bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis Keaktifan Belajar Pendidikan Agama Kristen Melalui Aplikasi Moodle Pada Masa Post-Pandemi Covid-19: Studi Kasus Siswa SMPN 17 Surakarta
Authors: Gabriel Kezia Eirene 
Published: April 2023

This research aims to determine students' active learning level in Christian religious education at SMP 17 Surakarta during the pandemic by using Moodle-based E-Learning as an application that can change a learning media into a web form. Moodle allows students to enter digital classrooms to access learning materials online. This research was conducted at SMP Negeri 17 Surakarta with 40 Christian students in grades 8 and 9. The research method used was a quantitative approach with data analysis using statistical rules with the help of questionnaires and SPSS 25 software. -Moodle-Based Learning effectively increases the learning activity of Christian Religious Education and Character Education subjects at SMP Negeri 17 Surakarta during the pandemic. From the analysis results, Moodle-Based E-Learning is predicted to increase learning activity in Christian Religious Education and Character Education at SMP Negeri 17 Surakarta in the future so that this application is representative for use in post-covid-19 learning. AbstrakPenelitian ini bertujuan untuk mengetahui tingkat keaktifan belajar siswa dalam pembe-lajaran pendidikan agama Kristen di SMP 17 Surakarta pada masa pandemi dengan menggunakan E-Learning berbasis Moodle sebagai aplikasi yang dapat merubah sebuah media pembelajaran ke dalam bentuk web. Moodle memungkinkan siswa untuk masuk ke dalam ruang kelas digital untuk mengakses materi-materi pembelajaran secara online. Penelitian ini dilaksanakan di SMP Negeri 17 Surakarta dengan jumlah sampel penelitian 40 orang siswa kristen kelas 8 dan 9. Adapun meto-de penelitian yang dipakai adalah pendekatan kuantitatif dengan analisa data menggunakan kaidah statistik dengan bantuan angket kuesioner dan software SPSS 25. Hasil penelitian ini menunjukan penggunaan E-Learning Berbasis Moodle efektif dalam meningkatkan Keaktifan belajar mata pelajaran Pendidikan Agama Kristen dan Budi Pekerti Di SMP Negeri 17 Surakarta pada masa pandemi serta dari hasil analisa penggunaan E-Learning Berbasis Moodle diprediksi akan memba-wa peningkatan Keaktifan belajar pada mata pelajaran Pendidikan Agama Kristen dan Budi Pekerti di SMP Negeri 17 Surakarta kedepannya sehingga aplikasi ini representatif untuk digunakan pada pembelajaran pasca pandemi covid-19.
PENGARUH MODEL PEMBELAJARAN BERBASIS MASALAH BERBANTUAN POSTER SESSION TERHADAP MINAT DAN HASIL BELAJAR IPS SISWA KELAS V
Authors: Syafaat Fifi Maghfira , B Roslaeny , Muslimin Aziz 
Published: April 2023

Pembelajaran dengan menggunakan model berbasis masalah merupakan salah satu dari banyak strategi pembelajaran inovatif. Model pembelajaran ini menyajikan suatu kondisi belajar peserta didik yang aktif serta melibatkan peserta didik dalam suatu pemecahan masalah melalui tahap-tahap metode ilmiah. Tujuan penelitian adalah untuk mengetahui pengaruh Model Pembelajaran Berbasis Masalah berbantuan Poster Session terhadap minat belajar dan hasil belajar IPS siswa kelas V. Jenis penelitian ini adalah Quasi Eksperimental Design dalam penelitian ini diberikan perlakuan tertentu (treatment), yaitu kelas kontrol dan kelas eksperimen. Jumlah sampel dalam penelitian ini adalah 40 murid. Metode pengumpulan data yang digunakan yaitu angket motivasi dan tes hasil belajar serta dokumentasi. Tehnik analisis data yang digunakan yaitu pertama dengan menggunakan pendekatan statistik deskriptif dan uji manova. Hasil penelitian menunjukkan bahwa minat belajar siswa kelas IV menunjukkan nilai yang signifikansi 0,700 berada diatas 0,05 hal ini berarti berdistribusi normal. nilai signifikansi hasil belajar siswa kelas IV adalah 0,646 lebih besar dari 0,05 hal ini menunjukkan bahwa ada pengaruh yang signifikan antara media pembelajaran berbasis masalah berbantuan poster session terhadap minat dan hasil belajar siswa kelas IV, dan berdasarkan uji manova multivariate dengan pengambilan keputusan bahwa nilai signifikan 0,00 < 0,05 maka dapat disimpulkan bahwa terdapat perbedaan minat belajar dan hasil belajar yang signifikan antara siswa yang belajar dengan menggunakan model pembelajaran berbasis masalah berbantuan poster session pada kelas eksperimen dengan siswa yang belajar secara konvensional pada kelas kontrol
E-MODUL TEMATIK UNTUK PEMBELAJARAN DARING SEKOLAH DASAR PASCA PANDEMI COVID-19
Authors: Herlina Herlina , Zulnuraini Zulnuraini , Gagaramusu Yusdin , Risma Iga , Harmila Harmila , Dwienengtyas Anggi 
Published: April 2023

Seiring berlalunya waktu dan menurunnya tingkat penyebaran virus corona, maka pembelajaran full online mulai bergeser menjadi pembelajaran campuran (blended learning). Proporsi online dan offline dalam pembelajaran campuran ditentukan oleh institusi dengan mempertimbangkan kesediaan sarana prasarana dan tingkat penyebaran virus corona di kota kabupaten atau provinsi masing-masing. Salah satunya adalah penyediaan sumber belajar berbasis digital sehingga dapat diakses oleh setiap pelajar kapan dan di manapun berada. Salah satu sumber belajar digital yang dipandang perlu dikembangkan saat ini adalah behan ajar dalam bentuk e-modul. E-modul bukanlah sesuatu yang baru dalam dunia pendidikan tanah air. Penelitian ini bertujuan mengeksplorasi kebutuhan e-modul di sekolah dasar sebagai dasar dan justifikasi pengembangan e-modul untuk pembelajaran tematik di kabupaten Sigi. Penelitian ini menggunakan rancangan penelitian fenomenologi sebagai analisis kebutuhan pengembangan e-modul. Subyek Sekolah Dasar di Kabupaten Sigi. Data dianalisis secara kualitatif dengan Teknik kondensasi data, penyajian data dan penarikan kesimpulan/verifikasi. Hasil penelitian menunjukkan bahwa kebutuhan pengembangan sumber belajar online berbentuk e-modul sangat tinggi dan merekomendasikan pengembangan e-modul tematik sekolah dasar untuk memenuhi kebutuhan belajar siswa sekolah dasar di Kabupaten Sigi.
Peculiarities of the some nematodoses course in turtles and tortoises under conditions of keeping in terrariums
Authors: Dubova O. , Feshchenko D. , Zghozinska O. , Dubovyi A. 
Published: April 2023

The article presents the results of studying the course of some nematodoses in turtles and tortoises kept in terrariums. Helminth infections account for 35 % of all parasitic diseases of reptiles and are a significant danger, especially after wintering and for weakened individuals. The purpose of the work is to establish the helminth fauna of turtles and clinical testing of the topical application of an anthelmintic on a lipophilic basis. Research methods are coprological, statistical. The greatest extensiveness and intensity of invasion were found in nematodes Tachygonetria spp. Wedi, 1862 (family Oxyuridae) and Angusticaecum spp. Baylis, 1920 (family Ascaridae). Identified pathogens under the conditions of wintering in terrariums and after it are able to cause manifested forms of the disease in connection with the stress experienced by turtles. Invasion of Tachigonetria spp. manifested by gastrointestinal disorders: diarrhea, regurgitation of feed, weakness. Parasitism of Angusticaecum spp. characterized in addition to disorders of the digestive system by signs of respiratory pathology: shortness of breath of the expiratory type, secretion of serous and serous-purulent exudate, snoring, coughing. The highest intensity of invasion by both genera of nematodes was found in the spring, in the period after wintering, and the lowest – in the summer, in the season of the hottest weather. During a clinical trial of the use of various anthelmintics and different ways of administering the drug, it was established that Panacur orally and Profender topically have high intensive efficacy, however, 100 % extensive efficacy was not found in both drugs. Topical application of Profender on a lipophilic basis showed better results of intensity, especially against Angusticaecum spp., than enteral administration of Panacur. High, but incomplete intensity effectiveness of both drugs against Tachigonetria spp. is explained by the extraordinary spread of the causative agent's eggs in the environment, their pronounced resistance to extreme environmental conditions, commensalism of nematodes. Preparations on a lipophilic basis for parenteral (topical) use have prospects for use in reptile veterinary medicine.
Panoramic radiograph measurement of upper mandibular ramus breadth for sex determination
Authors: Septiani Dinda Priscilia , Tanjung Rizki , Farizka Intan 
Published: April 2023

Objectives: This research is aimed to see the difference of the upper mandibular ramus breadth between male and female patients in Rumah Sakit Gigi dan Mulut Pendidikan (RSGMP) Fakultas Kedokteran Gigi Universitas Trisakti, West Jakarta according to radiomorphometry.
Materials and Methods: This research uses observational analytical design on 166 digital panoramic radiographs, 83 male radiographs and 83 female radiographs, of patients aged 18 and above from the Installation of Dental Radiology in RSGM-P FKG Universitas Trisakti. The measurement was performed on left upper mandibular ramus breadth using the computer software i-Dixel version 2.2.0.3 (Morita Japan). The data is analyzed using comparative independent t-tests to see the difference between the genders.
Results: The result of this study shows the mean value of the left upper mandibular ramus breadth in male (31.55 ± 2.66 mm ) is higher than female (29.42 ± 2.58 mm) with p-value = 0.000.
Conclusion: The upper mandibular ramus breadth measurement shows significant difference between genders.
Kết hợp tách tín hiệu và lựa chọn anten cho hệ thống STBC-OFDM đa người dùng
Authors: Đức Lê Quang , Tâm Bùi Thanh , Nam Trần Xuân 
Published: April 2023

OFDM and MIMO are the two transmission technologies which are recently being studied intensively. Combination of both technologies enables higher transmission rates over frequency selective fading channels. Alamouti’s STBC is one of MIMO technologies selected for mobile radio systems. This paper presents a method of multiuser detectionfor combined radio systems STBC-OFDM. By using the antenna selective technology proposed in the paper, the signal detection quality is enhanced considerably. The paper’s results also present those two methods, SNR-based and MSE-based antenna selection, providing the best performance.
Một giải pháp suy diễn câu trả lời trong hệ thống hỏi đáp thông tin
Authors: Tươi Phan Thị , Thành Nguyễn Chánh 
Published: April 2023

Question Answering (QA) is an important research field that research groups focuson to develop useful QA system for many languages in the world (English, Chinese, Japanese …) but just few for Vietnamese. One of most difficult processings in QAis the answer reasoning applying to natural language question, especially Vietnamese. The paper introduces an approach of reasoning answers for Vietnamese question based on Graph Theory and Artificial Intelligence (AI). The experimentation, which is done for Vietnamese questions in initial phase, shows that the proposed approach is feasible for Vietnamese and it can be upgraded more for other languages in future.
From Fenben to Digital Dunhuang Material Pool: Innovations in Art Production through Transformation of Producing Media
Authors: Ren Ruiqi 
Published: April 2023

Fenben was an indispensable medium for the ancient Dunhuang artisans before painting the wall. While Digital Dunhuang·Material Pool, which relies on 3D laser scanning, digital storage, and blockchain, is a new medium for art production in the advanced technological context. Combining desk research and case studies, using Fenben and the Digital Dunhuang·Material Pool as examples, this research focuses on the medium's origin, content, form, and application to practical art production, analyzing the prescriptive nature of the different mediums and their corresponding shaping of art production patterns. In conclusion, the research argues that the Digital Dunhuang·Material Pool echoes Fenben in an inter-temporal way while transforming the “readable” world of the Buddha on the wall into the “writable” cultural object on the blockchain, thus providing a compliant medium for cultural enthusiasts to create secondary artworks around Dunhuang, which is a vivid practice in the democratization of art production through the development of contemporary media.
EdeepSADPr: an extensive deep-learning architecture for prediction of the in situ crosstalks of serine phosphorylation and ADP-ribosylation
Authors: Jiang Haoqiang , Shang Shipeng , Sha Yutong , Zhang Lin , He Ningning , Li Lei 
Published: April 2023

The in situ post-translational modification (PTM) crosstalk refers to the interactions between different types of PTMs that occur on the same residue site of a protein. The crosstalk sites generally have different characteristics from those with the single PTM type. Studies targeting the latter’s features have been widely conducted, while studies on the former’s characteristics are rare. For example, the characteristics of serine phosphorylation (pS) and serine ADP-ribosylation (SADPr) have been investigated, whereas those of their in situ crosstalks (pSADPr) are unknown. In this study, we collected 3,250 human pSADPr, 7,520 SADPr, 151,227 pS and 80,096 unmodified serine sites and explored the features of the pSADPr sites. We found that the characteristics of pSADPr sites are more similar to those of SADPr compared to pS or unmodified serine sites. Moreover, the crosstalk sites are likely to be phosphorylated by some kinase families (e.g., AGC, CAMK, STE and TKL) rather than others (e.g., CK1 and CMGC). Additionally, we constructed three classifiers to predict pSADPr sites from the pS dataset, the SADPr dataset and the protein sequences separately. We built and evaluated five deep-learning classifiers in ten-fold cross-validation and independent test datasets. We also used the classifiers as base classifiers to develop a few stacking-based ensemble classifiers to improve performance. The best classifiers had the AUC values of 0.700, 0.914 and 0.954 for recognizing pSADPr sites from the SADPr, pS and unmodified serine sites, respectively. The lowest prediction accuracy was achieved by separating pSADPr and SADPr sites, which is consistent with the observation that pSADPr’s characteristics are more similar to those of SADPr than the rest. Finally, we developed an online tool for extensively predicting human pSADPr sites based on the CNNOH classifier, dubbed EdeepSADPr. It is freely available through http://edeepsadpr.bioinfogo.org/. We expect our investigation will promote a comprehensive understanding of crosstalks.
Consolidation of the perinatal care system and workload of obstetricians: an ecological study in Japan
Authors: Hattori Sanae , Sakata Nobuo , Ishimaru Miho , Tamiya Nanako 
Published: April 2023

ObjectivesWe examined the relationship between consolidation of delivery and the workload of obstetricians working at perinatal centers.MethodsWe conducted a descriptive analysis using perinatal care areas classified into three types (metropolitan, provincial, and rural). We calculated the Herfindahl–Hirschman Index (HHI) as an index of consolidation and the proportion of the deliveries at clinics as an indicator of the low-risk deliveries and the deliveries per center obstetrician as an indicator of obstetricians’ workload. We used &gt;150 deliveries yearly as an excess indicator. The correlation between the HHI and obstetricians' workload and the proportion of deliveries at clinics was examined using the Pearson correlation coefficient.ResultsThe proportion of areas with  &gt;150 deliveries yearly was higher in the consolidated areas. In provincial areas, obstetricians’ workload was positively correlated with the HHI and was negatively correlated with the proportion of deliveries at clinics.ConclusionsThe obstetricians' workload may be increasing where more consolidation occurs. In provincial areas, the center obstetrician's workload could be reduced not only by consolidation but also by sharing the role of handling low-risk deliveries with clinics and hospitals with obstetric units other than perinatal centers.
Fasting blood glucose, blood pressure and body mass index among combined oral contraceptive users in Chencha town Southern Ethiopia, 2019
Authors: Kofole Zelalem , Haile Diresbachew , Solomon Yerukneh 
Published: April 2023

BackgroundThe use of contraceptives has become prevalent among women in Ethiopia. Oral contraceptive use has been suggested to trigger changes in glucose metabolism, energy expenditure, blood pressure, and body weight, among various populations and ethnic groups.ObjectiveTo elucidate the pattern of fasting blood glucose, blood pressure, and body mass index among combined oral contraceptive pills users compared to controls.MethodsAn institution-based cross-sectional study design was employed. A total of 110 healthy women using combined oral contraceptive pills were recruited as cases. Another 110 healthy age and sex-matched women not using any hormonal contraceptives were recruited as controls. A study was conducted between October 2018 and January 2019. Data obtained was entered and analyzed using IBM SPSS version 23 software packages. One-way ANOVA was used to identify the variation of variables in relation to the duration of use of the drug. The P-value of &lt; 0.05 at the 95% confidence level was statistically significant.ResultsFasting blood glucose level among oral contraceptive users (88.55 ± 7.89 mg/dl) was higher than fasting blood glucose level among oral contraceptive non-users (86.00 ± 9.85 mg/dl) with a p-value of 0.025. The mean arterial pressure of oral contraceptive users (88.2 ± 8.48 mmHg) was relatively higher than their counterparts (86.0 ± 6.74 mmHg), with a p-value of 0.04. Comparatively the body weight and body mass index among oral contraceptive users were 2.5% and 3.9% higher than non-users with a p-value of 0.03 and 0.003, respectively(5). Utilization of oral contraceptive pills for prolonged period of time seemed to be a significant predictive factor for higher mean arterial pressure and body mass index with p &lt; 0.001and p &lt; 0.05 respectively.ConclusionsUse of combined oral contraceptives was associated with higher fasting blood glucose (+2.9%), mean arterial pressure (+2.5%), and body mass index (3.9%) compared to controls.
Novel compound heterozygous variants in EMC1 associated with global developmental delay: a lesson from a non-silent synonymous exonic mutation
Authors: Wang Ge , Wang Yanli , Gao Chao , Xie Wanqin 
Published: April 2023

BackgroundThe endoplasmic reticulum-membrane protein complex (EMC) as a molecular chaperone is required for the proper synthesis, folding and traffic of several transmembrane proteins. Variants in the subunit 1 of EMC (EMC1) have been implicated in neurodevelopmental disorders.MethodsWhole exome sequencing (WES) with Sanger sequencing validation was performed for a Chinese family, including the proband (a 4-year-old girl who displayed global developmental delay, severe hypotonia and visual impairment), her affected younger sister and her non-consanguineous parents. RT-PCR assay and Sanger sequencing were used to detect abnormal RNA splicing.ResultsNovel compound heterozygous variants in EMC1, including the maternally inherited chr1: 19566812_1956800delinsATTCTACTT[hg19];NM_015047.3:c.765_777delins ATTCTACTT;p.(Leu256fsTer10) and the paternally inherited chr1:19549890G&gt; A[hg19];NM_015047.3:c.2376G&gt;A;p.(Val792=) are identified in the proband and her affected sister. RT-PCR assay followed by Sanger sequencing reveals that the c.2376G&gt;A variant leads to aberrant splicing, with retention of intron 19 (561bp) in the mature mRNA, which is presumed to introduce a premature translational termination codon (p.(Val792fsTer31)).ConclusionNovel compound heterozygous variants in EMC1 have been identified in individuals with global developmental delay. Non-silent synonymous mutations should be kept in mind in genetic analysis.
Patterns, mechanism of injury and outcome of pediatric trauma at a level 1 trauma centre: a descriptive retrospective analysis
Authors: Alansari Amani N. , Mekkodathil Ahammed , Peralta Ruben , Baykuziyev Temur , Alhussaini Nour W. Z. , Asim Mohammad , El-Menyar Ayman 
Published: April 2023

BackgroundThere is a gap in knowledge on the epidemiology of pediatric trauma in the developing countries. We aimed to describe the injury pattern, mechanism of injury (MOI), and outcomes of pediatric trauma in a level 1 trauma centre in one of the Arab Middle Eastern countries.MethodsA retrospective analysis of pediatric injury data was conducted. All trauma patients (&lt;18 years old) requiring hospitalization between 2012 and 2021 were included. Patients were categorized and compared based on the MOI, age-group and injury severity.ResultsA 3,058 pediatric patients (20% of the total trauma admissions) were included in the study. The incidence rate in 2020 was 86 cases per 100,000 pediatric population in Qatar. The majority were male (78%) and the mean age was 9.3 ± 5.7 years. Nearly 40% had head injuries. The in-hospital mortality rate was 3.8%. The median injury severity score (ISS) (interquartile range; IQR) was 9 (4–14) and Glasgow coma scale (GCS) was 15 (IQR 15–15). Almost 18% required Intensive Care admission. Road Traffic Injuries (RTI) were more frequent in 15–18 years old whereas ≤4 years group was mostly injured by falling objects. The case fatality rate was higher among females (5.0%), and in 15–18 years (4.6%) and &lt;4 years (4.4%) group. Pedestrian injuries were more lethal among the MOI. One fifth had severe injury with a mean age of 11 ± 6 and 9.5% had ISS of ≥25. Predictors of severe injury were age (10 years old and above) and RTI.ConclusionAlmost one-fifth of the trauma admissions at the level 1 trauma centre in Qatar is due to traumatic injuries among the pediatric population. Developing strategies that are based on understanding the age- and mechanism-specific patterns of traumatic injuries among the pediatric population remains crucial.
Case report: Durable response to ruxolitinib in a child with TREX1-related disorder
Authors: Bin Khathlan Yasir , Almutairi Sajdi , Albadr Fahad B. , Alangari Abdullah A. , Alsultan Abdulrahman 
Published: April 2023

BackgroundJAK inhibitors are useful in treating interferonopathies, presumably because they downregulate the JAK/STAT signaling. There are limited studies about the safety and effectiveness of using JAK inhibitors in children with TREX1-related disorders.Case presentationWe report an 8-year-old female who presented at five years of age with features suggestive of hemophagocytic lymphohistiocytosis (HLH)-like disorder. The infectious disease workup was negative. Neurological assessment was normal. A brain CT scan was performed because of headache. It showed a faint subcortical calcification at right frontal lobe and almost symmetrical calcification within the basal ganglia. Brain MRI showed bilateral symmetrical globus pallidus, high T1 signal intensities, and a few scattered nonspecific FLAIR hyperintensities in subcortical and deep white matter. IVIG as an immune modulating agent was administered initially which led to the resolution of fever, improvement of blood count parameters, inflammatory markers, and normalization of liver enzymes. The child remained afebrile with no significant events for several months, then had disease flare up. The patient was started on pulse methylprednisolone 30 mg/kg for three days, then continued on 2 mg/kg. Whole exome sequencing revealed a novel heterozygous missense TREX1 mutation NM_016381.3:c.223G &gt; A p.(Glu75Lys). The child was started on ruxolitinib, 5 mg orally twice daily. The child has prolonged, durable remission after initiating ruxolitinib with no adverse effects. Steroids were tapered off and the patient is no longer on IVIG. The patient is still on ruxolitinib for more than two years.ConclusionThis case highlights the potential role of ruxolitinib in the treatment of TREX1-related disorders. A longer follow-up period is required to evaluate the long-term outcome.