bluuebunny/crossref_metadata_2025_split huggingface dataset:
Appraisal of an Innovative Surgical Approach in Treating Odontogenic
Keratocyst
Authors: Lenka Sthitaprajna , Bej Ananya , Nagarajappa Ramesh , Sahoo Swagata , Subudhi Santosh , Rathore Karishma , Rath Aditi Ava 
Published: May 2023

Objective:
To estimate the recurrence of odontogenic keratocyst (OKCs) and increment of bone height upon an innovative treatment protocol of the OKC, i.e., enucleation along with the adjuvant therapy of Carnoy’s solution, followed by marsupialization.

Methods:
Twenty cases of OKC treated at the Department of Oral and Maxillofacial Surgery from 2020-2021 were studied retrospectively. Clinical, radiological features and histologic features were reviewed. The patients diagnosed with OKCs were planned for enucleation with the use of Carnoy's solution and followed by marsupialization. Recurrence of the same and bone formation was analyzed concerning sites of involvement, based upon the gender and age group of patients, after undergoing the proposed treatment.

Results:
Mean age of the patients was 35.15±13.02, ranging from 11 to 56 years. Most (85%) patients were symptomatic, and the remaining (15%) were asymptomatic and diagnosed on a routine check-up. Males (65%) were mostly affected than females (35%). Mandible (75%) was the most frequent site of occurrence. Most lesions were diagnosed histologically as OKC on incisional biopsy. All patients were followed for six months, an increment of 11.11±1.68mm bone height was seen, and none reported recurrence.

Conclusions:
The steady growth of bone without any cases of recurrence was reported. Hence, clinicians can consider enucleation along with adjuvant therapy using Carnoy's solution followed by marsupialization as the treatment of choice.
Prevalence and Prognostic Factors of Cortical Laminar Necrosis in Acute
Ischemic Stroke
Authors: Wang Zhi-li , Qin Wei , Lyu Yuelei , Hu Wenli 
Published: May 2023

Background:
Cortical laminar necrosis (CLN) is a specific type of cortical infarction,
and little is known about its frequency and outcomes. We aimed to investigate the prevalence and
outcomes of CLN caused by brain infarction and its prognostic factors.

Methods:
This retrospective cohort study included patients with acute ischemic stroke (AIS) between
2019 and 2022 and for whom magnetic resonance images obtained at our center showed
acute-stage CLN. Their medical records were collected and analyzed. An unfavorable outcome
was defined as a modified Rankin Scale score of 3-6 at 90 days. Logistic regression was performed
to identify independent predictors of an unfavorable outcome.

Results:
Among 5548 consecutive patients with AIS, 151 patients (2.7%) were diagnosed with
CLN, and 112 had CLN enrolled in the final analysis. At 90 days, 25 patients (22.3%) had an unfavorable
outcome. Compared with the favorable group, poor outcome patients had higher rates of
previous stroke (p = 0.012), higher National Institutes of Health Stroke Scale (NIHSS) scores at
admission (p < 0.001), and were more likely to have early neurologic deterioration (END) (p =
0.014), diffuse ischemic lesions (p = 0.011), and lesions involving multiple lobes (p = 0.030). In
multivariable analysis, the initial NIHSS score (OR, 1.258, [95% CI 1.090 - 1.453], p = 0.002) and
END (OR, 5.695, [95% CI 1.410 - 23.007], p = 0.015) were independently associated with unfavorable
outcome.

Conclusion:
CLN is a rare ischemic event but has a good prognosis in most cases. A higher initial
NIHSS score and END may predict an unfavorable outcome.
Using Baidu Index Data to Improve Chickenpox Surveillance in Yunnan, China: Infodemiology Study
Authors: Wang Zhaohan , He Jun , Jin Bolin , Zhang Lizhi , Han Chenyu , Wang Meiqi , Wang Hao , An Shuqi , Zhao Meifang , Zhen Qing , Tiejun Shui , Zhang Xinyao 
Published: May 2023

Background
Chickenpox is an old but easily neglected infectious disease. Although chickenpox is preventable by vaccines, vaccine breakthroughs often occur, and the chickenpox epidemic is on the rise. Chickenpox is not included in the list of regulated communicable diseases that must be reported and controlled by public and health departments; therefore, it is crucial to rapidly identify and report varicella outbreaks during the early stages. The Baidu index (BDI) can supplement the traditional surveillance system for infectious diseases, such as brucellosis and dengue, in China. The number of reported chickenpox cases and internet search data also showed a similar trend. BDI can be a useful tool to display the outbreak of infectious diseases.

Objective
This study aimed to develop an efficient disease surveillance method that uses BDI to assist in traditional surveillance.

Methods
Chickenpox incidence data (weekly from January 2017 to June 2021) reported by the Yunnan Province Center for Disease Control and Prevention were obtained to evaluate the relationship between the incidence of chickenpox and BDI. We applied a support vector machine regression (SVR) model and a multiple regression prediction model with BDI to predict the incidence of chickenpox. In addition, we used the SVR model to predict the number of chickenpox cases from June 2021 to the first week of April 2022.

Results
The analysis showed that there was a close correlation between the weekly number of newly diagnosed cases and the BDI. In the search terms we collected, the highest Spearman correlation coefficient was 0.747. Most BDI search terms, such as “chickenpox,” “chickenpox treatment,” “treatment of chickenpox,” “chickenpox symptoms,” and “chickenpox virus,” trend consistently. Some BDI search terms, such as “chickenpox pictures,” “symptoms of chickenpox,” “chickenpox vaccine,” and “is chickenpox vaccine necessary,” appeared earlier than the trend of “chickenpox virus.” The 2 models were compared, the SVR model performed better in all the applied measurements: fitting effect, R2=0.9108, root mean square error (RMSE)=96.2995, and mean absolute error (MAE)=73.3988; and prediction effect, R2=0.548, RMSE=189.1807, and MAE=147.5412. In addition, we applied the SVR model to predict the number of reported cases weekly in Yunnan from June 2021 to April 2022 using the same period of the BDI. The results showed that the fluctuation of the time series from July 2021 to April 2022 was similar to that of the last year and a half with no change in the level of prevention and control.

Conclusions
These findings indicated that the BDI in Yunnan Province can predict the incidence of chickenpox in the same period. Thus, the BDI is a useful tool for monitoring the chickenpox epidemic and for complementing traditional monitoring systems.
Automated Diet Capture Using Voice Alerts and Speech Recognition on Smartphones: Pilot Usability and Acceptability Study
Authors: Chikwetu Lucy , Daily Shaundra , Mortazavi Bobak J , Dunn Jessilyn 
Published: May 2023

Background
Effective monitoring of dietary habits is critical for promoting healthy lifestyles and preventing or delaying the onset and progression of diet-related diseases, such as type 2 diabetes. Recent advances in speech recognition technologies and natural language processing present new possibilities for automated diet capture; however, further exploration is necessary to assess the usability and acceptability of such technologies for diet logging.

Objective
This study explores the usability and acceptability of speech recognition technologies and natural language processing for automated diet logging.

Methods
We designed and developed base2Diet—an iOS smartphone application that prompts users to log their food intake using voice or text. To compare the effectiveness of the 2 diet logging modes, we conducted a 28-day pilot study with 2 arms and 2 phases. A total of 18 participants were included in the study, with 9 participants in each arm (text: n=9, voice: n=9). During phase I of the study, all 18 participants received reminders for breakfast, lunch, and dinner at preselected times. At the beginning of phase II, all participants were given the option to choose 3 times during the day to receive 3 times daily reminders to log their food intake for the remainder of the phase, with the ability to modify the selected times at any point before the end of the study.

Results
The total number of distinct diet logging events per participant was 1.7 times higher in the voice arm than in the text arm (P=.03, unpaired t test). Similarly, the total number of active days per participant was 1.5 times higher in the voice arm than in the text arm (P=.04, unpaired t test). Furthermore, the text arm had a higher attrition rate than the voice arm, with only 1 participant dropping out of the study in the voice arm, while 5 participants dropped out in the text arm.

Conclusions
The results of this pilot study demonstrate the potential of voice technologies in automated diet capturing using smartphones. Our findings suggest that voice-based diet logging is more effective and better received by users compared to traditional text-based methods, underscoring the need for further research in this area. These insights carry significant implications for the development of more effective and accessible tools for monitoring dietary habits and promoting healthy lifestyle choices.
AJWAIN SEEDS AS CAPPING AGENT FOR Bi2O3 NANOFLAKES: SYNTHESIS AND GROWTH INHIBITING EFFICIENCY OF BACTERIA
Authors: SETHURAMAN BHARANI DHARAN , CHANDRASEKAR LAKSHMI PRABHA , SUBRAMANI MANIKANDAN , ANILKUMAR ASWATHY KARANATH , GANESH MUNUSWAMY-RAMANUJAM , MOHANDOS SIVAKAMI 
Published: May 2023

Objective: This work is mainly focused to determine the antibacterial activity of the green synthesized Bi2O3 nanoparticles against the bacterial strains, Staphylococcus aureus and Escherichia coli using resazurin as indicator.
Methods: Bismuth oxide nanoparticles were synthesized from the precursor bismuth nitrate [Bi (NO3)3.5H20] by using trachyspermum ammi (ajwain) seed extract. To carry out these works, the synthesized Bi2O3 NPs undergone characterizations and were confirmed by UV-Vis, FT-IR, XRD, SEM and EDAX, TGA-DTA and DLS. Biological activity was done using a well diffusion method.
Results: Bi2O3 NP's has been tested against bacteria (S. aureus and E. coli) in wells and shows blue colour, indicating bacterial growth inhibition in a dose-dependent manner for different concentrations.
Conclusion: The biological studies were done with one gram-positive and one gram-negative bacteria to show the inhibiting efficiency. The synthesized bismuth oxide nanoparticles showed good anti-bacterial activity (different concentrations) against S. aureus and E. coli.
DEVELOPMENT OF NOVEL 1, 3, 4-THIADIAZOLES AS ANTITUBERCULAR AGENTS-SYNTHESIS AND IN VITRO SCREENING
Authors: THOMAS ANCY , B. VINOD , K. U. SNEHA SHENOY , M. V. VISHNU 
Published: May 2023

Objective: Tuberculosis, known in short as TB, is considered to be a global crisis caused by Myco bacterium tuberculosis, and which continues to be a serious challenge to public health world wide especially in the developing countries. A serious problem related to tuberculosis is the development of drug resistant strains.
Methods: Present study describes the synthesis of eight novel derivatives of 1,3,4-thiadiazole derivatives and in vitro evaluation of their anti tubercular activity against Mycobacterium tuberculosis H37 Rv strain by alamar blue assay. Pyrazinamide and Streptomycin were the standards, used for the evaluation.
Results: Among the eight compounds synthesized one derivative was found to be active against the strain tested. All the other derivatives tested exhibited negligible activity against the strain.
Conclusion: It can be concluded that novel 1, 3, 4-thiadiazole derivatives can be developed as novel agents in the fight against TB.
Learning Representations of Satellite Images with Evaluations on Synoptic Weather Events
Authors: Yo Ting-Shuo , Su Shih-Hao , Wu Chien-Ming , Chen Wei-Ting , Chu Jung-Lien , Chang Chiao-Wei , Kuo Hung-Chi 
Published: May 2023

This study applied representation learning algorithms to satellite
images and evaluated the learned latent spaces with classifications of
various weather events. The algorithms investigated include the
classical linear transformation, i.e., principal component analysis
(PCA), state-of-the-art deep learning method, i.e., convolutional
autoencoder (CAE), and a residual network pre-trained with large image
datasets (PT). The experiment results indicated that the latent space
learned by CAE consistently showed higher threat scores for all
classification tasks. The classifications with PCA yielded high hit
rates but also high false-alarm rates. In addition, the PT performed
exceptionally well at recognizing tropical cyclones but was inferior in
other tasks.
Further experiments suggested that representations learned from
higher-resolution datasets are superior in all classification tasks for
deep-learning algorithms, i.e., CAE and PT. We also found that smaller
latent space sizes had little impact on the classification task’s hit
rate. Still, a latent space dimension smaller than 128 caused a
significantly higher false-alarm rate.
Though the CAE can learn latent spaces effectively and efficiently, the
interpretation of the learned representation lacks direct connections to
physical attributions. Therefore, developing a physics-informed version
of CAE can be a promising outlook for the current work.
Implementación de aula invertida: desempeño académico de estudiantes universitarios en un curso de lectura de textos en inglés
Authors: Jiménez Rivas José Ramón 
Published: May 2023

Actualmente, el modelo de aula invertida ha adquirido un inusitado auge, en gran medida debido a la situación generada por el virus SARS-CoV-2 que todavía afecta al mundo entero. El interés en esta metodología se debe a la combinación de otros constructos importantes en educación, como el aprendizaje autodirigido, centrado en el alumno, desempeño escolar, entre otros, así como las tecnologías de la información y la comunicación (TIC) en el aula. Aunque existen muchas investigaciones sobre el uso del modelo de aula invertida y la comprensión de lectura en inglés, estas se centran principalmente en cursos generales de inglés y no abordan la instrucción exclusiva de comprensión lectora de textos en inglés, lo que representa una problemática muy particular en el aprendizaje de lenguas extranjeras.
Este trabajo de investigación abordó la intervención con el modelo de aula invertida para un curso de comprensión lectora en inglés dirigido a estudiantes de primer ingreso en una universidad situada al norte de la Ciudad de México. El estudio fue de corte cuantitativo con diseño cuasi-experimental con pre y pospruebas para comprobar si la mencionada intervención mejoraba el desempeño de los estudiantes. La muestra no aleatoria estuvo conformada por 63 estudiantes de ambos sexos. A partir del análisis estadístico con la prueba U de Mann-Whitney, se encontró que la diferencia en el desempeño académico con el modelo de aula invertida y la enseñanza tradicional no es estadísticamente significativa (U = 454, p = .938, r = 0.01).
Spiritual Intelligence with TQN Zikr Method
Authors: El Bilad Cecep Zakarias , Rahman Abd. , Arifin Samsul 
Published: May 2023

Spirituality is a human spiritual aspect that determines the quality of attitudes and behavior. A lot of cases of immorality are caused by weak spiritual intelligence. Therefore, such intelligence needs to be seriously improved. One of the methods that can be used is reciting zikr (remembrance). This research proves that practicing zikr can have a positive effect on mental condition. This research was conducted at a student boarding school in Palangka Raya who practiced the zikr of the Qadiriyah Naqsyabandiyah Order (TQN). This research is descriptive qualitative as well as quantitative. The result proves that TQN Zikr has a positive impact on the spiritual intelligence of its practitioners. TheÂ practitioners show the improvement in emotional management, caring, patience, and honesty.
Bioinformatics Approach for Metabolism Pathways Curation: Carbohydrate Metabolism and TCA Cycle in the Archaeon Sulfolobus solfataricus P2
Authors: Khayatt Barzan Ibrahim 
Published: May 2023

Background: Metabolic and genomic informatics integrations in organism-specific databases require comprehensive and intensive efforts. PathoLogic, a component of the Pathway Tools software package can create complete Pathway/Genome Databases (PGDBs) from genomic sequence and annotation files for any organism. This tool can predict the metabolic pathways using MetaCyc as a reference knowledge base. This work aimed to apply a bioinformatics approach to curate a PGDB created for the Crenarchaeon Sulfolobus solfataricus P2. This archaeon grows optimally at 80o C and pH 2-4. The complete genome of S. solfataricus P2 was released in 2001. Created PGDBs often need manual curations to fill in the metabolic gaps that the software failed to detect.
Methods: We used Pathway Tools to create the PGDB for the Sulfolobus solfataricus P2. Bioinformatics curation for carbohydrate metabolism pathway (Entner-Doudoroff “ED”) and TCA cycle was carried out. Literature search as well as homology-, orthology- and context-based protein function prediction methods were followed for this curation using the Editors component of the Pathway Tools program.
Results: Curation modified the number of the pathways in the database by adding extra pathways that have not been detected by the PathoLogic. New pathways such as semi-phosphorylated ED and a new variation of the TCA cycle were added to the PGDB of S. solfataricus P2. Filling in the metabolic holes (missing enzymes) in the pathways under study was also involved in the curation process.
Conclusion: The bioinformatics curation of the PGDB of S. solfataricus P2 improved the database that can serve as a reference knowledge base for genomic annotations and metabolic pathway reconstructions of other organisms especially the closely related Archaea.
Role of T. vulgaris in protection DNA damage induced by Lead acetate in Rats
Authors: Ghazi Maysam A. , Al-Qaiym Majida A. 
Published: May 2023

Objective: The purpose of this study was to investigate Thymus vulgaris (T.vulgaris) ethanolic extract protective role for lymphocytes viability and prevent DNA damage by long-term exposure to Lead acetate (Pb) via ingestion.
Material and method: A number of 24 females adult rats were divided into equal groups; 1st Group, as control, 2nd Group administered with lead acetate 5 mg/kg B.W oral gavage lead acetate for 60 days and 3rd Group treated with lead acetate at dose 5mg/kg B.W and T.vulgaris extract at doses 75mg/kg B.W for 60 days.
Result: Results of leukocytes (WBCs) and lymphocyte count revealed a significant (P≤0.05) decrease in the 2nd group and an increase in the 3rd group in comparison to the 1st group. Also the result of Lymphocyte/Neutrophil ratio increased significantly (P≤0.05) in the 2nd and 3rd groups as compared to the 1st group. lymphocytes viability were evaluated using trypan blue, showed statistically (P≤0.05) less viable lymphocytes cells were in the 2nd group and more viable lymphocytes cells were found in the 3rd group when comparing to 1st group. Ingestion of T.vulgaris showed a protective role in preventing DNA damage according to comet assay.
Conclusion the ethanolic T.vulgaris polyphenols extracted molecules with their unique chemical molecular structure withstand lead toxicity, could be due to chelate lead activity.
WAJAH BARU PENDIDIKAN ANAK USIA DINI PASCA PANDEMI COVID-19
Authors: Marlisa Lusi , Noormawanti Noormawanti , Firdausyi Annisa Nur 
Published: May 2023

Diskursus kemunculan wajah baru dalam dunia pendidikan anak tentunya akan menjadi suatu topik baru yang menjadi penentu saat ini dalam dunia pendidikan. Setiap segi dimensi kehidupan mengalami disrupsi baik dari adanya pandemic dan revolusi industry digital yang begitu signifikan dengan adanya pandemic. penelitian ini menggunakan jenis penelitian kualitatif dengan pendekatan studi kasus (case study) untuk mendapatkan gambaranterkait dengan permasalahan di atas, maka peneliti mengambil lokasi penelitian di kota Metro. Pemilihan lokasi penelitian tersebut sengaja dilakukan secara purposive sampling dan mendapatkan sekitar 7 sekolah sebagai responden.Teknik pengumpulan data yang di gunakan yakni menggunakan wawancara dengan menyiapkan instrument penelitian berupa butir-butir pertanyaan terbuka melalui google form. Lebih lanjut instrumen tersebut kemudian disebarkan melalui daring kepada guru dan kepala sekolah. Setelah dilakukannya penyebaran instrumen secara daring, peneliti memiliki sebanyak 20 responden diantaranya adalah guru-guru dan kepala sekolah PAUD, untuk melihat tanggapan wajah baru dalam pembelajaran anak usia dini setelah new normal covid-19. Hasil penelitian yang di dapati, bahwasanya salah satu upaya yang dilakukan yakni sekolah, masyarakat serta pemerintah terus saling bahu-membahu untuk menggerakkan upaya pemulihan pasca pandemic, dengan harapan keberlangsungan pembelajaran di sekolah tetap berjalan, harapan tersebut tentunya akan dapat menguatkan kemitraan antara masyarakat, orangtua, dan pemerintah dalam menanggulangi pasca pandemi.
La dialéctica entre lo civil y lo militar en la China antigua
Authors: Galvany Albert 
Published: May 2023

Gran parte de los estudios recientes dedicados a la historia política e intelectual de la China antigua consideran que el recurso explícito a la violencia o a la coacción es un rasgo exclusivo de los autores adscritos al legismo (fa jia 发家) o al pensamiento militar (bing jia 兵家) es decir, a los teóricos que podríamos describir y clasificar mediante el término realpolitik; mientras que las propuestas vinculadas al confucianismo se inclinarían por formas de gobierno más indulgentes, basadas en una actuación principalmente pedagógica así como en la eficacia de una autoridad de orden moral.
Gladis Nieto, <em>La inmigración china a España: una comunidad ligada a su nación</em>, Madrid, Libros de la Catarata, 2007, 217 pp.
Authors: Campos R. Ivonne 
Published: May 2023

Gladis Nieto, La inmigración china a España: una comunidad ligada a su nación, Madrid, Libros de la Catarata, 2007, 217 pp.
Intestinal infection with Echinococcus multilocularis in a dog
Authors: Jenkins Emily J. , Kolapo Temitope U. , Jarque Maria P. , Ruschkowski Cecilia , Frey Caroline 
Published: May 2023

Abstract

OBJECTIVE
To raise veterinary awareness of a newly recognized parasitic threat to canine and human health, highlight the increasing availability of molecular parasitological diagnostics and the need to implement best practices of cestocidal use in high-risk dogs.

ANIMAL
A young Boxer dog with vomiting and bloody diarrhea, suspected diagnosis of inflammatory bowel disease.

CLINICAL PRESENTATION, PROGRESSION, AND PROCEDURES
Bloodwork revealed inflammation, dehydration, and protein loss, addressed with supportive therapy. Fecal culture revealed only Escherichia coli. On centrifugal flotation, tapeworm eggs (which could be Taenia or Echinococcus spp) and, unusually, adult cestodes of Echinococcus were observed. The referring veterinarian was contacted to initiate immediate treatment with a cestocide due to zoonotic potential. Diagnosis was confirmed with a coproPCR which has higher sensitivity for Echinococcus spp than fecal flotation alone. DNA was identical to an introduced European strain of E multilocularis currently emerging in dogs, people, and wildlife. Since dogs can also self-infect and develop hepatic alveolar echinococcosis (severe and often fatal), this was ruled out using serology and abdominal ultrasound.

TREATMENT AND OUTCOME
Following cestocidal treatment, fecal flotation and coproPCR were negative for eggs and DNA of E multilocularis; however, coccidia were detected and diarrhea resolved following treatment with sulfa-based antibiotics.

CLINICAL RELEVANCE
This dog was serendipitously diagnosed with E multilocularis, acquired through ingestion of a rodent intermediate host likely infected from foxes and coyotes. Therefore, as a dog at high risk of reexposure from eating rodents, regular (ideally monthly) treatment with a labeled cestocide is indicated going forward.