bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kemoterapiye Bağlı Gelişen Bulantı Kusma Yönetimine İlişkin Hemşirelik Alanında Yapılmış Deneysel Tezlerin İncelenmesi
Authors: PEHLİVAN Zeynep , GÜLHAN GÜNER Seçil , NURAL Nesrin 
Published: April 2023

Amaç: Bu sistematik incelemede, kemoterapiye bağlı gelişen bulantı-kusma semptomu yönetimine ilişkin Türkiye’de hemşirelik alanında yapılmış deneysel lisansüstü tez çalışmalarının gözden geçirilmesi amaçlanmıştır.
Yöntem: Bu çalışmada, Yüksek Öğretim Kurumu Ulusal Tez Merkezi veri tabanında 01.01.2010-31.12.2020 tarih aralığında “kemoterapi ve semptom”, “kemoterapi ve bulantı-kusma” anahtar kelimeleri kullanılarak tarama yapılmıştır. Araştırmaya hemşirelik alanında yapılan ve tamamına erişilebilen, örneklemi 18 yaş ve üzeri olan, yayın dili Türkçe olan, deneysel tipte yapılan ve içeriğinde bulantı-kusma semptomu yer alan toplam 23 tez çalışması dahil edilmiştir.
Bulgular: İncelenen tez çalışmaları sonuçlarına göre, hemşireler tarafından bulantı-kusma yönetimine ilişkin hastalara akupresür, solunum egzersizi, progresif gevşeme egzersizi, zencefil, ayak refleksolojisi, aromaterapi, müzik terapi gibi nonfarmakolojik yöntemler uygulandığı ve eğitim verildiği saptanmıştır. Uygulanan solunum egzersizi, zencefil, progresif gevşeme egzersizi, müzik terapi, akupresür, ayak refleksolojisi ve aromaterapi uygulamalarının ve verilen hasta eğitimlerinin bulantı-kusma sayısını ve bulantı şiddetini azalttığı belirlenmiştir.
Sonuç: İntegratif yaklaşımlar arasında yer alan refleksoloji, progresif gevşeme egzersizi, solunum egzersizleri vb. uygulamaların ve hasta eğitimlerinin kemoterapiye bağlı bulantı-kusma yönetiminde kullanılabilecek etkili yöntemler olduğu belirlenmiştir.
İntramüsküler Enjeksiyon Ağrısını Azaltmaya Yönelik Bölge ve Yöntemler İle İlgili Tezler: Sistematik Bir Derleme
Authors: İNCE Merve , TUNCER Metin , KHORSHİD Leyla 
Published: April 2023

Amaç: Bu çalışma, Türkiye’de yetişkinlerde intramüsküler enjeksiyon sırasında ağrıyı azaltmaya yönelik kullanılan nonfarmakolojik yöntemler ve enjeksiyon bölgeleri ile ilgili yapılan tezlerin incelenmesi amacıyla yapılmıştır.
Yöntem: Çalışmanın evrenini Ağustos-Ekim 2021 tarihlerinde, intramüsküler enjeksiyonlarla ilgili anahtar kelimeler kullanılarak, “Yükseköğretim Kurulu Ulusal Tez Merkezi” veri tabanında yıl sınırlaması olmaksızın hemşirelik alanında yapılan 35 kayıtlı tez oluşturmuştur. Yapılan tarama sonucunda, bu tezlerden araştırma kriterlerini karşılayan 16 lisansüstü tez çalışma kapsamına alınmıştır.
Bulgular: Tezlerin çoğunluğunun yüksek lisans tezi olduğu (n=13), tezlerin deneysel (n=9) ve yarı deneysel (n=7) tasarımda yapıldığı ve tezlerin tümünün örneklem grubunu hastaların oluşturduğu belirlenmiştir. İntramüsküler enjeksiyonlarda kullanılan birçok nonfarmakolojik yöntemin (n=11) olduğu ve bu yöntemlerin çoğunun (n=9) intramüsküler enjeksiyona bağlı ağrıyı azalttığı ve hasta memnuniyetini arttırdığı belirlenmiştir. Ayrıca intramüsküler enjeksiyonlarda ventrogluteal bölgenin tercih edilmesinin de (n=2) enjeksiyona bağlı ağrıyı azalttığı ve buna ek olarak hasta memnuniyetini arttırdığı saptanmıştır.
Sonuç: Ventrogluteal bölgede, dorsogluteal bölgeye göre daha az ağrı hissedilmesi ve hasta memnuniyetinin yüksek olması nedeniyle ventrogluteal bölgenin tercih edilmesi önerilmektedir. Ek olarak intramüsküler enjeksiyonlarda ağrıyı azaltmada etkili oldukları için ekstremitelerin internal rotasyonu, lokal soğuk uygulama, shotblocker, soğuk sprey, buzzy, z yolu tekniği gibi yöntemlerin kullanılması önerilmektedir.
COVID-19 Pandemi Sürecinde Demanslı Bireylere Bakım Veren Aile Üyelerinin Sağlık Okuryazarlık Düzeyleri ve İlişkili Faktörler
Authors: AKYOL Merve Aliye , AKPINAR SÖYLEMEZ Burcu , ÖZGÜL Ecem 
Published: April 2023

Amaç: Bu araştırma COVID-19 pandemi sürecinde demanslı bireylere bakım veren aile üyelerinin sağlık okuryazarlık düzeyleri ve ilişkili faktörlerini incelemek amacıyla yapılmıştır.
Yöntem: Tanımlayıcı tipteki araştırma Ekim-Kasım 2021 tarihleri arasında demanslı bireylere bakım veren 114 aile üyesiyle yürütülmüştür. Araştırmada amaçlı örneklem yöntemi kullanılmıştır. Veriler; tanımlayıcı özellikler formu, Avrupa Sağlık Okuryazarlığı Ölçeği (ASOY-TR) ve COVID-19 Korkusu Ölçeği kullanılarak toplanmıştır. Verilerin değerlendirilmesi araştırmacılar tarafından SPSS 24.0 programı kullanılarak yapılmıştır. Değerlendirmede sayı, yüzde, ortalama, One-way ANOVA testi ve ki-kare testi kullanılmıştır.
Bulgular: Araştırmaya katılan demanslı bireylere bakım verenlerin yaş ortalaması 55.90±10.72 yıl (min-maks:20-79), %82.5’i kadın, %66.7’sinin geliri giderine eşit, %55.4’ü lisans mezunudur. Bakım verenlerin %34.2’sinin yeterli ve mükemmel düzeyde sağlık okuryazarlığına sahip olduğu bulunmuştur. Bakım veren bireylerin genel sağlık okuryazarlığı puan ortalamalarının, çalışma ve eğitim durumlarının sağlık okuryazarlık düzeyleri üzerinde istatistiksel açıdan anlamlı bir fark oluşturduğu (p0.05) görülmüştür.
Sonuç: Çalışma COVID-19 pandemi sürecinde demanslı bireylere bakım veren aile üyelerinin sağlık okuryazarlık düzeylerine ve ilişkili faktörlere ışık tutmaktadır. Bu sonuçlar doğrultusunda özellikle çalışmayan ve düşük eğitim seviyesi olan bakım verenlerin sağlık okuryazarlık düzeylerinin geliştirilmesi önerilmektedir. Ayrıca bakım verenlerin üçte ikisinin yetersiz ve sorunlu-sınırlı düzeyde sağlık okuryazarlığına sahip olduğu ortaya konmuştur. Sağlık profesyonellerinin demanslı bireye bakım veren aile üyelerinin sağlık bilgilerine etkin bir şekilde erişmesine, anlamasına, değerlendirmesine ve uygulamasına yardımcı olmaları önerilmektedir.
Constraints on the Cosmological Coupling of Black Holes from the Globular Cluster NGC 3201
Authors: Rodriguez Carl L. 
Published: April 2023

Abstract
Globular clusters are among the oldest stellar populations in the Milky Way; consequently, they also host some of the oldest known stellar-mass black holes, providing insight into black hole formation and evolution in the early (z ≳ 2) universe. Recent observations of supermassive black holes in elliptical galaxies have been invoked to suggest the possibility of a cosmological coupling between astrophysical black holes and the surrounding expanding universe, offering a mechanism for black holes to grow over cosmic time and potentially explaining the origin of dark energy. In this paper, I show that the mass functions of the two radial velocity black hole candidates in NGC 3201 place strong constraints on the cosmologically coupled growth of black holes. In particular, the amount of coupling required to explain the origin of dark energy would either require both NGC 3201 black holes to be nearly face on (a configuration with probability of at most 10−4) or one of the BHs would need to have formed with a mass below that of the most massive neutron stars (2.2 M
⊙). This emphasizes that these and other detached black hole–star binaries can serve not only as laboratories for compact object and binary astrophysics but as constraints on the long-term evolution of astrophysical black holes.
Sensorialité et hallucinatoire dans le psychisme du psychanalyste de famille et de couple. Communication préliminaire
Authors: Eiguer Alberto , Darchis Élisabeth , Granjon Evelyn , Grinspon Eduardo , Bass Henri-Pierre , Marques-Lito Ana , Lopez-Minotti Véronique , Chéné Alain 
Published: April 2023

Les auteurs présentent une recherche en cours depuis 2017 sur les manifestations sensorielles chez l’analyste familial et leur élaboration. L’objet d’étude est le psychisme des mêmes psychanalystes familiaux qui réalisent la recherche ; ils vont évoquer leur contre-transfert lors du processus de leurs cas cliniques, leurs associations, sentiments, idées, rêveries. Ce récit se fait en groupe par visioconférence et en intervision des cas présentés. Aussi bien la groupalité que l’intervision permettent une régulation critique des expressions contre-transférentielles et le ménagement des principes de la recherche empirique : explication et compréhension par des tiers, vérification, doute, refusabilité. Ainsi le groupe s’installe-il dans un état régressif de suspension du jugement. La pensée groupale peut alors prendre de l’essor, la chaîne associative groupale, la synchronisation topique, l’accordage intersubjectif, la sollicitation de nos préconscients vont ouvrir vers des horizons inattendus. Les cas étudiés laissent entendre que la co-sensorialité est fertile en découvertes sur le fonctionnement familial inconscient ; elle assure et dynamise l’implication émotionnelle des patients et thérapeutes favorisant la création du néo-groupe ; les effets thérapeutiques sont notoires. Deux vignettes cliniques illustrent ce travail.
Analogies à visée argumentative dans les romans graphiques traitant de la Shoah
Authors: Adler Silvia 
Published: April 2023

Cette contribution examine le fonctionnement des analogies à visée argumentative dans les supports multimodaux que sont la bande dessinée et le roman graphique, et plus particulièrement dans les romans graphiques qui traitent de la Shoah, pour répondre aux questions de savoir (a) à quoi est dû le poids argumentatif de ces analogies et comment elles participent à la construction d’un argument, et (b) ce qui caractérise les procédures analogiques construites dans l’« art séquentiel ».
Discours d’influenceurs, discours d’autorité ? Le cas de deux médecins influenceurs sur Twitter
Authors: Vicari Stefano 
Published: April 2023

Dans cette étude, je voudrais démontrer, par une étude de cas, les procédés et les stratégies techno-discursives déployées par deux médecins influenceurs pour créer un discours d’autorité dans Twitter. D’abord, je présente le cadre théorique au prisme duquel j’appréhende la notion d’autorité, au croisement des conceptions développées par Oger (2021) en analyse du discours, par Origgi en épistémologie sociale (2008) et par Broudoux en sciences de l’information et de la communication (2007), ainsi que des études de cas menées par moi-même (Vicari, 2021, 2021b, 2022) en analyse du discours. Cela me permettra de cerner les éléments fondant ce qu’on peut considérer comme une relation d’autorité que je me propose d’analyser, dans un second temps, dans un corpus de tweets issus des comptes d’un nano-influenceur de santé (Le DrMus) et d’une micro-influenceuse de santé (Marine Lorphelin) ; tous deux sont de jeunes médecins particulièrement actifs sur Twitter depuis le début de la pandémie du Covid-19. Mon objectif est de montrer que loin d’effacer tout type d’autorité, les dispositifs numériques, et notamment Twitter, favorisent l’essor de relations de confiance à partir de manifestations de l’autorité se situant à mi-chemin entre les paramètres technologiques des dispositifs et les pratiques discursives.
Cooperative but Distinct Role of Medullary Thymic Epithelial Cells and Dendritic Cells in the Production of Regulatory T Cells in the Thymus
Authors: Morimoto Junko , Matsumoto Minoru , Oya Takeshi , Tsuneyama Koichi , Matsumoto Mitsuru 
Published: April 2023

Abstract
Regulatory T cells (Tregs) are produced in the thymus to establish self-tolerance, and agonistic stimuli by self-Ags play a pivotal role in this process. Although two types of APCs, medullary thymic epithelial cells (mTECs) and dendritic cells (DCs), are responsible for presenting self-Ags together with costimulatory/cytokine signals, the distinct role of each APC in producing Tregs remains enigmatic. We have approached this issue by depleting the mTECs and DCs using mice expressing diphtheria toxin receptors driven by Aire and CD11c promoters, respectively. Depletion of mTECs showed an effect on Treg production quantitatively and qualitatively more profound than that of DCs followed by the development of distinct organ-specific autoimmune lesions in the hosts. Because self-Ags produced by mTECs are transferable to DCs through a process known as Ag transfer, we monitored the process of Ag transfer using mice expressing GFP from TECs. Although GFP expressed from total TECs was effectively transferred to DCs, GFP expressed from cortical TECs was not, suggesting that mTECs are the predominant source of self-Ags. We also found that GFP expressed not only from mature mTECs but also from immature mTECs was transferred to DCs, suggesting that a broad spectrum of molecules were subjected to Ag transfer during mTEC development. Interestingly, the numbers of recirculating non-Tregs producing IL-2, an important source for Treg expansion in the thymus, were reduced only in the mTEC-depleted mice. These results suggested the cooperative but distinct role of mTECs and DCs in the production of Tregs to avoid autoimmunity.
Myocardial Immune Cells: The Basis of Cardiac Immunology
Authors: Cohen Charles D , Rousseau Sylvie T , Bermea Kevin C , Bhalodia Aashik , Lovell Jana P , Zita Marcelle Dina , Čiháková Daniela , Adamo Luigi 
Published: April 2023

Abstract
The mammalian heart is characterized by the presence of striated myocytes, which allow continuous rhythmic contraction from early embryonic development until the last moments of life. However, the myocardium contains a significant contingent of leukocytes from every major class. This leukocyte pool includes both resident and nonresident immune cells. Over recent decades, it has become increasingly apparent that the heart is intimately sensitive to immune signaling and that myocardial leukocytes exhibit an array of critical functions, both in homeostasis and in the context of cardiac adaptation to injury. Here, we systematically review current knowledge of all major leukocyte classes in the heart, discussing their functions in health and disease. We also highlight the connection between the myocardium, immune cells, lymphoid organs, and both local and systemic immune responses.
Gender differences in burden of care and coping strategies among caregivers of schizophrenia patients
Authors: Kumar Santosh , Dixit Vidhata , Ali Ramjan , Chaudhury Suprakash 
Published: April 2023

ABSTRACT

Background:
Caregivers of patients with schizophrenia have a considerable burden of care and develop different coping strategies to deal with the caregiving burden.

Aim:
The aim of this article is to assess gender differences in the burden of care and coping strategies used among caregivers of clinically stable patients with schizophrenia.

Methods:
In this cross-sectional study, a total of 57 caregivers (33 males and 24 females) of the patients with schizophrenia attending a psychiatric outpatient setting were included by purposive sampling. The caregivers were assessed with the Burden Assessment Schedule 20 items (BAS-20) and Brief Approach/Avoidance Coping Questionnaire (BACQ) to assess the burden of care and coping strategies, respectively.

Results:
Average BAS-20 score was comparable between the male and female caregivers. If the patient was a spouse, the male caregivers had a significantly higher burden of the marital relationship than the female caregivers. On the BACQ, the socio-emotional approach subscale was significantly higher in female caregivers. The avoidance-oriented coping score and socio-emotional avoidance subscale were significantly higher in male caregivers. A significant positive correlation was found between BAS-20 score and avoidance-oriented coping scores in all caregivers except the females where a significant negative correlation was found between BAS score and socio-emotional avoidance type of coping.

Conclusion:
There are no gender differences in the burden of care in caregivers of clinically stable patients with schizophrenia except the male caregivers have a higher burden in the domain of marital relationship. The socio-emotional approach type of coping is higher in females while the socio-emotional avoidance type of coping is lower in male caregivers.
Peripheral ulcerative keratitis secondary to chronic Citrobacter koseri canaliculitis
Authors: Hsieh Hsiu-Hui , Shen Elizabeth P. 
Published: April 2023

Abstract

Citrobacter
koseri is a rarely reported ocular pathogen. It may induce severe peripheral corneal inflammation and subsequent perforation by canaliculitis. Timely detection of the reservoir of this pathogen would halt its progression. The purpose of this study was to report a rare presentation of C. koseri chronic canaliculitis complicated with perforating peripheral ulcerative keratitis (PUK). A 71-year-old female who had several episodes of C. koseri conjunctivitis in the past 6 months was admitted to our infection ward under the impression of fever that was suspected to be related to urinary tract infection. She had concurrent copious mucopurulent discharge and blurred vision. Ocular examination disclosed hyperemic conjunctiva and an oval-shaped corneal infiltrate at 5–6 o’c periphery, which later rapidly progressed to PUK and corneal perforation. Despite aggressive treatment, the cornea continued to thin, and a second perforation occurred. After meticulous examination of the ocular adnexa, irrigation of inferior canaliculi revealed pustular discharge with profuse concretions indicating chronic canaliculitis. A cutaneous-lacrimal fistula was also found. Frequent antibiotic irrigation of the canaliculus finally halted the corneal melting and the cornea healed. Although rare, C. koseri may not only cause chronic canaliculitis but also induce peripheral corneal inflammation mimicking autoimmune-related PUK. Identification of C. koseri from conjunctival swab cultures should prompt the physicians to check chronic persistent canaliculus infections, which may help prevent rapidly progressive corneal inflammation and thus perforation. Management of C. koseri canaliculitis-induced PUK must also include antibiotic irrigation to eradicate canaliculitis infection at the reservoir and not just topical antibiotics.
Improving Narrative Feedback for Resident-Led Academic Rounds: The Effects of Assessment Form Design Changes
Authors: Courtis Sara , Rachul Christen , Fotti Sarah , Fleisher Wil 
Published: April 2023

ABSTRACT

Background
Learners benefit more from narrative feedback than numerical scores on formative assessments, yet they often report that feedback is lacking in quality and quantity. Changes to the formatting of assessment forms is a practical intervention with limited literature regarding its impact on feedback.

Objective
This study explores the effect of a formatting change (ie, relocating the comment section from the bottom of a form to the top) on residents' oral presentation assessment forms and if this affects the quality of narrative feedback.

Methods
We used a feedback scoring system based on the theory of deliberate practice to evaluate the quality of written feedback provided to psychiatry residents on assessment forms from January to December 2017 before and after a form design change. Word count and presence of narrative comments were also assessed.

Results
Ninety-three assessment forms with the comment section at bottom and 133 forms with the comment section at the top were evaluated. When the comment section was placed at the top of the evaluation form, there were significantly more comment sections with any number of words than left blank (X2(1)=6.54, P=.011) as well as a significant increase in the specificity related to the task component, or what was done well (X2(3)=20.12, P≤.0001).

Conclusions
More prominent placement of the feedback section on assessment forms increased the number of sections filled as well as the specificity related to the task component.
How Do Postgraduate Trainees Prepare for New Clinical Learning Environments?
Authors: Gifford Kimberly A. , Kieffer Kelly A. , Choi Eunjung 
Published: April 2023

ABSTRACT

Background
Transitioning to a new clinical learning environment (CLE) requires learning new skills, roles, teams, workflows, and culture. We previously identified activities and questions to guide orientation in the categories of who, what, where, when, why, and how. There is limited literature about how learners plan for this transition.

Objective
Describe how postgraduate trainees prepare for a clinical rotation, based on qualitative analysis of narrative responses within a simulated orientation experience.

Methods
In June 2018, incoming residents and fellows in multiple specialties at Dartmouth Hitchcock Medical Center completed an online simulated orientation that asked how they intended to prepare for their first rotation. We used directed content analysis to code their anonymously collected responses using the orientation activities and question categories from our prior study. We used open coding to describe additional themes.

Results
Narrative responses were available for 97% (116 of 120) of learners. While 46% (53 of 116) of learners listed preparations related to what happens in the CLE, responses fitting into other question categories were less frequent: who (9%, 11 of 116), where (7%, 8 of 116), when (4%, 5 of 116), why (&lt;1%, 1 of 116), and how (0%, 0 of 116). Learners also infrequently described activities to aid the transition: reading orientation materials (11%, 13 of 116), speaking with a colleague (11%, 13 of 116), and arriving early (3%, 3 of 116). They more frequently commented on content reading (40%, 46 of 116), asking for advice (28%, 33 of 116), and self-care (12%, 14 of 116).

Conclusions
When describing preparation for a new CLE, residents focused on tasks in the what category more than understanding the system and learning goals in other categories.
A Qualitative Study on the Outcomes of Participation in a Longitudinal Clinician Educator Curriculum During Internal Medicine Residency
Authors: Yang Yihan , Sankey Christopher , Gielissen Katherine 
Published: April 2023

ABSTRACT

Background
Despite increasing prevalence of longitudinal clinician educator tracks (CETs) within graduate medical education (GME) programs, the outcomes of these curricula and how participation in these tracks affects early career development remains incompletely understood.

Objective
To describe the experience and outcomes of participating in a CET and its effects on recent internal medicine residency graduates' perceived educator skills and early career development.

Methods
We conducted a qualitative study between July 2019 and January 2020 using in-depth semi-structured interviews of recently graduated physicians from 3 internal medicine residencies at one academic institution who had participated in a CET, the Clinician Educator Distinction (CED). Iterative interviews and data analysis was performed via an inductive, constructionist, thematic analysis approach by 3 researchers to develop a coding and thematic structure. Results were sent electronically to participants for member checking.

Results
From 21 (out of 29 eligible) participants, thematic sufficiency was reached at 17 interviews. Four themes related to the CED experience were identified: (1) motivation to go beyond the expectations of residency; (2) educator development outcomes from Distinction participation; (3) factors enabling curricular efficacy; and (4) opportunities for program improvement. A flexible curriculum with experiential learning, observed teaching with feedback, and mentored scholarship allowed participants to enhance teaching and education scholarship skills, join a medical education community, transform professional identities from teachers to educators, and support clinician educator careers.

Conclusions
This qualitative study of internal medicine graduates identified key themes surrounding participation in a CET during training, including positively perceived educator development outcomes and themes surrounding educator identity formation.