bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effectiveness of Diode Lasers in the Reduction of Bacteremia Associated with Ultrasonic Scaling: A Clinical and Microbiological Study
Authors: Verma Vartika , Ojha Moitri , Yadav Sweta , Ranjan Maitreyi , Hassan Sahba , Dhull Kanika S. 
Published: July 2023

ABSTRACT

Introduction:
As is known, periodontal pathogens and their products as well as inflammatory mediators produced in periodontal tissues might enter the bloodstream, causing systemic effects and/or contributing to systemic diseases.

Aim:
To evaluate the effect of diode lasers on the incidence of bacteremia associated with ultrasonic scaling and its clinical efficacy as an adjunct to scaling in the treatment of moderate periodontitis.

Result:
The use of diode laser is more effective in killing or detoxifying periodontopathic bacteria such as P. gingivalis associated with chronic periodontitis as compared to ultrasonic alone with ablate bacteria only when it comes in contact with plaque biofilm directly.

Conclusion:
The results of study confirm the previously reported findings that bacteremia is caused by ultrasonic scaling and adjunct use of diode laser with scaling has the potential to reduce the bacteremia associated with ultrasonic scaling alone.
Comparative Evaluation of the Efficacy of Two Modes of Delivery of Diclofenac for the Management of Post-Endodontic Pain: A Randomized Controlled Clinical Trial
Authors: Dheeraj Munish , Johar Suksham , Mahajan Priya , Jandial Tania , Chauhan Shikha , Gupta Kamakshi 
Published: July 2023

ABSTRACT

Background:
This study aimed to compare the efficacy of two modes of delivery of diclofenac for the management of post-endodontic pain.

Materials and Methods:
This study comprised 30 patients reporting to the department with pain in their teeth. Pain was assessed using the visual analog scale (VAS): group A (control group), group B (oral diclofenac), and group C (transdermal patch). A VAS was given to the patients in each group, and the severity of any pain was self-assessed by patients after 4 hrs, 8 hrs, 12 hrs, 24 hrs, and 48 hrs following the completion of treatment.

Results:
A comparison between group oral and diclofenac transdermal patch was carried out. The pain frequency was measured at 4 hrs, 8 hrs, 12 hrs, 24 hrs, and 48 hrs postoperatively with P values of 0.744, 0.035, 0.570, 0.060, and 0.508 and was statistically insignificant.

Conclusion:
Preoperative analgesics play an important role in reducing post-endodontic pain. Transdermal patches containing diclofenac show a promising analgesic modality in managing endodontic pain.
Retinopathy of Prematurity: Incidence and Risk Factor Analysis in Small for Gestational Age Neonates Compared to Appropriate for Gestational Age
Authors: Arora Priyanka , Mahapatra Madhushmita , Arora Kamaldeep 
Published: July 2023

ABSTRACT

Objective:
To analyze the incidence of retinopathy of prematurity (ROP) among preterm neonates who were born small for gestational age (SGA) and appropriate for gestational age (AGA).

Materials and Methods:
A prospective cohort study among preterm neonates born <34 weeks of gestational age (GA) and <2000 grams birth weight (BW) was conducted. The neonates were divided into AGA and SGA group. Incidence of ROP and risk factors was compared among the groups.

Result:
290 neonates were screened [AGA: 240 (82.8%); SGA: 50 (17.2%)]. The mean birth-weight and gestational age were 1510.7 ± 390.64 grams and 31.4 ± 4.8 weeks, respectively. The incidence of ROP in AGA and SGA was 30.2% and 33%, respectively (P = 0.58), whereas the incidence of type 1 ROP in AGA and SGA was 14% and 19% (P = 0.41). Male sex, anemia, oxygen administration, surfactant administration, sepsis, and PIH were independent significant risk factors for ROP on multivariate analysis.

Conclusion:
This study showed that both AGA and SGA premature infants have similar incidence of ROP. SGA is not an independent risk factor for ROP.
Knowledge, Attitude, and Practice of Patients toward Dental Implants in Need of Prosthodontic Rehabilitation
Authors: Madhuri V , Kumararama Sindhu S. , Aradya Anupama , Byrappa Brijesh , Singh Kamlesh , Dixit Arti , Kumar Amit , Badiyani Bhumika K. 
Published: July 2023

ABSTRACT

Background:
Our goal in conducting this study was to see how well-informed patients are about dental implants as a method of prosthodontic rehabilitation.

Materials and Methods:
“In this cross-sectional study, 500 new dental students were asked questions using a pre-made, self-administered questionnaire. A pilot study was carried out to verify the reliability of the survey instrument. Analysis of the data was performed in SPSS 16 (SPSS). We used the P 0.05 thresholds for the Student’s T-test and the ANOVA to determine statistical significance.”

Results:
In all, there were 500 people involved: 320 men and 180 women. The media and dentists were the two most common places to learn about implants, and as patients received more information, they became more informed consumers. Many people put off getting therapy because of how expensive it is.

Conclusion:
Only a small percentage of individuals had implants, and more than half knew nothing about them. This finding also highlighted the need of educating patients more thoroughly on this therapy option. As a result, the public has to be educated about oral health and implants in order to adopt a more favorable perspective.
Fetal Humeral Diaphyseal Length in the Second Trimester – A Radiographic Observational Study among Indian Population
Authors: Kaur Maninder , Sharma Ravikant , Kapoor Kanchan , Kaur Ravinder , Arora Karandeep S. 
Published: July 2023

ABSTRACT

Objectives:
The present study was performed to provide a normal reference range for humerus diaphysis length at the second trimester of pregnancy in an Indian population.

Materials and Methods:
This cross-sectional study was performed on 25 radiographs of aborted normal human fetuses of gestational age (GA) between 13th and 28th weeks. The radiographs were used to measure the maximum length of the humerus using a vernier calliper. Data were collected, tabulated, and statistically analyzed.

Results:
The mean diaphyseal length of humerus at the fourth lunar month was 22.18 ± 6.59 mm, and at the seventh lunar month, it was 41.39 ± 10.08 mm. Simple linear regression analysis shows a strongly significant linear relationship of humerus length with GA, biparietal diameter, head circumference, and abdomen circumference.

Conclusion:
We have provided a normal reference range for humerus diaphysis length at the second trimester of pregnancy in an Indian population.
To Evaluate the Clinical Efficacy of 940 nm Diode Laser and Propolis Gel (A Natural Product) in Adjunct to Scaling and Root Planing in Treatment of Chronic Periodontitis
Authors: Aggarwal Rajni , Bawa Supneet S. , Palwankar Pooja , Kaur Simratjot , Choudhary Deepika , Kochar Deepak 
Published: July 2023

ABSTRACT

Background:
Recently, various adjunctive treatment options along with Scaling and root planing (SRP) such as local drug delivery, medications, and lasers have been introduced for the treatment Chronic periodontitis (CP) but literature is limited.

Aim:
To evaluate the clinical efficacy of 940 nm diode laser and propolis gel in adjunct to Scaling and root planing (SRP) in the treatment of CP.

Subjects and Methods:
Randomized clinical trial was conducted among 30 CP patients with a probing depth of ≥5 mm was allocated randomly into Group 1 (SRP), Group 2 (SRP + diode laser), and Group 3 (SRP + propolis gel). Plaque index, gingival index, pocket probing depth, and clinical attachment level were assessed at baseline, one and three months. Data analysis was performed using SPSS version 17 for windows, and statistical techniques employed were repeated measures by using One-way ANOVA, Tukey’s HSD, independent t-test, and paired t-test.

Results:
Post-treatment sites among all the three groups showed statistically significant reduction in Periodontal index (PI), Probing pocket depth (PPD), and Clinical attachment level (CAL), whereas gingival inflammation was significantly reduced in groups 2 and 3 from baseline to one and three months. On comparison, at baseline, all clinical parameters were statistically insignificant. At one month, the mean difference of PI, Gingival index (GI) was statistically significant between group 1 and 2 whereas the mean difference of CAL and PPD were statistically significant from group 1 to groups 2 and 3.

Conclusions:
Lasers with SRP were greatly effective in reducing gingival inflammation, PPD, and CAL. Propolis gel also offered encouraging and promising clinical results but still needs further long-term studies to establish its precise role in the treatment of CP.
Evaluation of Salivary Opiorphin, pH and Flow Rate in Oral Submucous Fibrosis - A Case - Control Observational Study
Authors: Varsha K. S. , Lakshmi Krithika C. , Ganesan Anuradha , Kannan A. , Aniyan K. Yesoda 
Published: July 2023

ABSTRACT

Aim and Objectives:
The aim of the study was to evaluate the salivary pH, flow rate and opiorphin in Oral submucous fibrosis patients and to compare them with healthy individuals.

Materials and Methods:
A comparative study was conducted to evaluate the salivary opiorphin levels, pH and flow rate among 78 patients (39 Oral submucous fibrosis + 39 control). Burning sensation was assessed using VAS score. Opiorphin levels were assessed using Cusabio Human Salivary Opiorphin ELISA kit. Salivary flow rate was assessed using graduated syringes and salivary pH was assessed using Hydrion salivary pH strips. Kolmogorov-Smirnov and Shapiro Wilk test were assessed for normality testing and distribution. Inferential statistics was done by using Unpaired t test/Independent sample t test to compare the mean values of variables included in the study among the OSMF and healthy patients.

Results:
There was statistically significant difference in pH and flow rate with a reduction in the mean pH (p=0.024) and flow rate (p<0.01) among the oral submucous fibrosis patients compared to the control group. A statistically significant increase (p<0.01) in salivary opiorphin levels was noted in the oral submucous fibrosis patients. Majority of the study participants had mild to moderate burning sensation.

Conclusion:
This study was a pilot evaluation of salivary opiorphin in OSMF. Salivary opiorphin could be used as an objective marker for chronic subjective conditions The pre-treatment and post treatment evaluation of salivary opiorphin could provide more insight on its role.
Formulation and Characterization of Mupirocin Nanomicelles in Insulin-Based Gel for Dermatological Application
Authors: Zubairi Maysaa B. , Abd Abdulkareem H. , Al-lami Mohammed S. 
Published: July 2023

ABSTRACT

Aim:
To produce and analyze mupirocin nanomicelle (MP-NM) in insulin-based gel.

Procedures:
MP-NM was prepared using solvent evaporation with Tween 80 as a surfactant. HPMC polymer prepared gel. MP-NM was characterized by globular diameter, polydispersity index (PDI), pH, entrapment efficiency (EE), and transmission electron microscopy (TEM). NM MP release was studied in vitro.

Results:
The revolutionary MP-NM in insulin-based gel dissolves MP completely without precipitation due to its unique physical and chemical properties. MP had 8.64 ± 0.2 nm globular diameter, high EE (98.85 ± 0.01%), and normal homogeneous dispersion (PDI, 0.143 ± 0.003) in NM. MP’s formula showed rapid first-order kinetics release.

Conclusion:
To our knowledge, this is the first MP-NM nano-drug delivery system employing insulin-based gel. It has promising pre-clinical and clinical uses.
Correlation between Neonatal Outcomes and Maternal Anemia among Attending Pregnant Women in Al-Elwiya Maternity Teaching Hospital
Authors: Hamood Mona A. , Abid Sahar Jassim , Abdulla Thikra N. , Akram Weqar 
Published: July 2023

ABSTRACT

Background:
Anemia in pregnancy can considerably elevate the maternal mortality risk and can negatively distress the development of fetus.

Object of the Current Work:
To assess the association between neonatal outcomes and maternal anemia (MA) among pregnant women (PW).

Subjects and Methodology:
The present work is a clinical prospective one performed at Al-Elwiya Maternity Teaching Hospital in Baghdad from January 1, 2022 to June 30, 2022. Current study selected 120 term PW with anemia admitted to hospital for caesarian section. Data were collected as a questionnaire. The data were directly taken from PW. The acquired data from anemic PW were distributed as followings: Age of anemic PW, which was classified into two groups; 25–29 years and 30–35 years. The gestational age of anemic PW, which was categorized into three groups; 37th week, 38th week, and 39th week of gestation. Anemia characteristics were studied, which included hemoglobin level (Hb) and packed cell volume test (PCV), which were done by taking 5 ml blood from each PW for s. ferritin, s.iron, Hb level, and blood film in laboratory of Al-Elwiya Maternity Teaching Hospital. The Hb helped in detecting anemic PW joined this study, as Hb was <10.5 g/dl at third trimester.

Results:
Mean gestational age (GA) of anemic PW was 37.5 ± 0.5 weeks; 58.3% of them were at 37th week, 39.2% of them were at 38th week, and 2.5% of them were at 39th week GA. So, the mean Hb of anemic PW was 8.6 ± 1.3 mg/dl, and the mean PCV was 28.6 ± 3.6%. Anemia was classified into mild (20%) and moderate (72.5%); also, mean ultrasound fetal head circumference (HC) among PW with mild anemia was 32.3 cm and for PW with moderate anemia was 32.1 cm, and mean ultrasound fetal abdominal circumference (AC) for PW with mild anemia was 31.3 cm and with moderate anemia was 31 cm, and validity results of MCA/UA-PI ratio regarding severe anemia of anemic were as follows: sensitivity (81.8%), specificity (79.8%), +ve predictive value (29%), −ve predictive value (97.8%), and accuracy (80%).

Conclusion:
The gestational mean age (GA) of anaemic PW was 37.50.5 weeks; 58.3% of them were in the 37th week and 39.2% were in the 38th week. Thus, the mean ultrasound foetal head circumference (HC) was 32.3 cm for PW with mild anemia and 32.1 cm for those with moderate anaemia. The mean ultrasound foetal abdominal circumference (AC) was 31.3 cm for those with mild anaemia and 31 cm for those with moderate anaemia, but 30 cm for those with severe anaemia, with no discernible difference. The following were the MCA/UA-PI ratio’s validity findings for severe anaemia of anaemic: sensitivity (81.8%) and specificity (79.8%).
Age Estimation using Cephalometrics—A Cross-Sectional Study among Teenagers of Salem District, Tamil Nadu
Authors: Murali Kruthika , Nirmal R. Madhavan , Balakrishnan Sekar , Shanmugam Shankar , Altaf Syed Khalid , Nandhini D 
Published: July 2023

ABSTRACT

Background:
Age estimation is important not only in identifying dead body of a person but also in living persons since there is an increasing rate of juvenile delinquencies recorded every year. To avoid foul play by age fabrication, legal age estimation becomes important. Facial growth alteration takes place in the jawbones as age advances which can be observed with lateral cephalometry. Thus, the aim of the study is to create a regression formula for age estimation using cephalometrics of teenagers in Salem population.

Materials and Methods:
A cross-sectional study was done using 770 lateral cephalometrics of teenagers (13–19 yrs) in Salem population. Nine cephalometric points with two linear hard tissue measurements (condylion to mandibular plane (AFH) and palatal plane to menton (PFH)) and one angular soft tissue measurement (z angle) were recorded as predictor variables using a digital lateral cephalometric software (Carestream CS8100 SC) which were subjected to regression analysis using SPSS version 21.0 to develop a formula for age estimation.

Results:
Significant association on age was obtained for the two linear measurements. The regression formula generated for estimating the age was Age = 7.146 + 0.044 (AFH) + 0.146 (PFH) with R2 value = 0.674

Conclusion:
Within the limitations of the present study, age estimation of teenagers in Salem population can be estimated. The predictability of the age can be increased by taking more cephalometric variables in generating the formula with increase in sample size.
Comparison of Amnion Membrane and Hyaluronic Acid in Gingival Recession Coverage and Gain in Clinical Attachment Level following Coronally Advanced Flap Procedure—A Clinical Study
Authors: Bagde Hiroj , Pawar Sangeeta K. , Vasisth Diwakar , Vadvadgi Vinay H. , Laddha Rashmi B. , Wagh Pradnya P. 
Published: July 2023

ABSTRACT

Background:
Gingival recession is defined as the apical migration of gingival margin to the cementoenamel junction. Recently, amnion membrane, the third-generation membrane which is a placental-derived tissue, has been introduced.

Materials and Methods:
Study included 45 subjects with age group of 20–60 years of both genders. Patients with Miller’s Class I and Class II gingival recession were selected for the study. The progress was assessed at baseline one, three, and six months observation interval through clinical parameters RD, RW, PD, and CAL at the end of six months.

Results:
Recession depths in the first, third, and sixth month were 1.82 ± 0.442, 1.31 ± 0.47 mm, and 0.91 ± 0.29, respectively, which showed a significant reduction from the baseline. Recession widths in the first, second, and third weeks were 3.04 ± 0.442 mm, 1.31 ± 0.47 mm, and 1.49 ± 0.59 mm, respectively. There was a statistically significant reduction (P > 0.005) when compared to the baseline. Pocket depths in the first, third, and sixth month were 0.93 ± 0.447, 0.42 ± 0.50, and 0.24 ± 0.43 (P > 0.005) which is significant when compared to baseline. Clinical attachment levels in the first, third, and sixth month were 2.73 ± 0.751, 1.78 ± 0.70, and 1.18 ± 0.53 (P > 0.005) which is significant compared to six months.

Conclusion:
Within the limitations of the present study, the data obtained by periodic assessment of the clinical parameters indicate the use of amnion membrane and hyaluronic acid, and proper technique may thus be the panacea for root coverage procedure.
Assessment of Corrected QT Interval and QT Dispersion in Patients with Uncomplicated Metabolic Syndrome
Authors: Kaur Amandeep , Kaur Navdeep , Madhukar Mohit 
Published: July 2023

ABSTRACT

Aim:
Metabolic syndrome (MS) itself has become a new entity being a constellation of physiological, biochemical, metabolic, and clinical factors that have been related to an increased risk of cardiovascular diseases, type 2 diabetes mellitus (T2DM), and morbidity and mortality. The burden of MS is increasing all over the world with the current prevalence being 30%. The QT interval and QT dispersion (QTd) have been long associated with ventricular arrhythmia and sudden cardiac deaths. The association between QT and diabetes and healthy subjects has been clearly studied, but the association between QT and uncomplicated MS has not been very well defined.

Methods:
A total of 400 patients visiting the medicine clinics were assessed for blood pressure, anthropometric measurements, fasting serum lipid profile, FBS, and electrocardiogram (ECG). The patients diagnosed with uncomplicated MS as per the International Diabetic Federation (IDF) criteria were included in the study. QT interval in the ECG was recorded, and the relationship between various parameters of an uncomplicated MetS and the QT interval was recorded.

Results:
Our study revealed more females with uncomplicated MS as compared to males and increasing burden as age progressed. Body mass index (BMI), waist circumference (WC), hip circumference (HC), WHP, systolic blood pressure (SBP), Diastolic blood pressure (DBP), Fasting blood sugar (FBS), serum cholesterol, triglyceride (TG), and low-density lipoprotein (LDL) levels were positively correlated with QT values.

Conclusion:
QT interval, a strong predictor of malignant ventricular arrhythmias and sudden cardiac deaths, is associated with uncomplicated MS.
Flap versus Flapless Immediate Implants with Bone Augmentation: A Novel Study
Authors: Choudhary Deepak , Girdhar Gaurav , Kumar Santosh , Shetty Arvind , Shetty Neetha J. , Sinha Sachin 
Published: July 2023

ABSTRACT

Background:
This study aimed to equate implants placed using a traditional flap elevation technique with implants placed using a flapless process regarding bone healing and success in clinical conditions.

Materials and Methods:
Sixty subjects were included in this research work. The participants were randomly divided into two groups. Patients in group A underwent implant placement with the flap elevation technique. Similarly, group B patients underwent implant placement without flap reflection. Parameters such as plaque index, wound healing index, crestal bone loss, and radiograph were considered to estimate the effectiveness of the two techniques.

Results:
Plaque indexes were improved in both groups. The modified gingival index also improved in all the phases of healing. The flapless method showed a better crestal bone.

Conclusion:
It can be concluded that this study showed that with the right augmentation techniques, implants could be successfully performed immediate extraction sockets, both with and without elevation of the mucoperiosteal flap.
Comparison of Two High Dose Rate Brachytherapy Regimes
Authors: Jaswal Gaurav , Benipal Raja , Bhatty Seema G. , Garg Pardeep , Kang Manraj S. 
Published: July 2023

ABSTRACT

Background:
Two HDR brachytherapy regimes were compared, 9.5 Gray per fraction for two fractions and 7.5 Gray per fraction for three fractions.

Materials and Methods:
A total of 80 patients with histologically evident squamous cell carcinoma cervix were taken in the current research after randomization. Radiotherapy dose delivered was 50 Gray/25#/5 weeks with concomitant chemotherapy with weekly cisplatin 35 mg/m2. Following external chemoradiation, patients were randomized into two arms. In Arm A, 40 patients were given high dose rate (HDR) brachytherapy of weekly 7.5 Gray in three fractions over 3 weeks. In Arm B, 40 patients were given high dose rate (HDR) brachytherapy of weekly 9.5 Gray in two fractions over 2 weeks. BED and LQED had been calculated, and the evaluation of response and consequences was examined.

Results:
In Arm A, BED to point A was 99.38 ± 0.00 and EQD2 to point A was 82.81 ± 0.00. In Arm B, BED to point A was 97.05 ± 0.00 and EQD2 to point A was 80.89 ± 0.00. With respect to rectum in Arm A, BED rectum was 108.66 ± 11.43 and EQD2 rectum was 65.07 ± 6.84. In Arm B, BED rectum was 107 ± 10.83 and EQD2 rectum was 64.21 ± 6.49. Similarly in Arm A, BED bladder was 107.86 ± 10.23 and EQD2 bladder was 64.59 ± 6.13. In arm B, BED bladder was 104.14 ± 10.79 and EQD2 bladder was 62.36 ± 6.46.

Conclusion:
In a follow-up of 6 months, no statistical significance in terms of local control as well as complications rates in both the arms. Our research demonstrates that two fractions of HDR are comparable with three fractions of HDR.
A Comparison of the Wetting Ability of Three Artificial Saliva Substitutes on Heat-Cured Denture Base Resin – An In vitro Study
Authors: Ranjan Madhu , Keshari Mritunjay Kumar , Sinha Tushar , Bhatia Mehtaab Singh , Rani Priya , Prakash Jayant 
Published: July 2023

ABSTRACT

Introduction:
Salivary substitutes are gaining popularity these days because of the increase in patients with dry mouth. These substitutes must satisfy certain criteria to fulfill the patient’s needs. One of these is wettability.

Materials and Methods:
One hundred fifty rectangular specimens of heat-cured denture base acrylic resin were prepared. A drop of test liquids (human saliva, distilled water, aqwet, saleva, and wet mouth) was placed over the test specimen and right and left contact angles were measured using optical contact angle machine.

Results:
All test liquids performed better than distilled water. Human saliva has the least contact angle followed by aqwet.

Conclusion:
Carboxymethyl cellulose base aqwet saliva substitute was found to be best having similar contact angle values to human saliva.