bluuebunny/crossref_metadata_2025_split huggingface dataset:
Health and social professional practices to promote family health literacy: an umbrella review protocol
Authors: Leavy Emma , Forestier Aline , Pugliese Marie-Thérèse , Coulon Delphine 
Published: February 2023

Abstract

Background Not only health literacy is central in achieving the sustainable development goals, but there is a growing interest with the COVID-19 pandemic and the insecurities brought about climate change. Personal knowledge and competencies in health literacy are mediated by the organizational structures and availability of resources. There is a lack of effective interventions promoting health literacy. Knowing that health decisions often occur within the family, we aim to review all existing reviews on professional psychosocial interventions which are effective in promoting health literacy among children, adolescents, and their families.
Methods We will search the following databases: MEDLINE via Pubmed, EMBASE, CINHAL, PsycINFO and Web of Science. We include all cultures and socioeconomic contexts (low- middle- and high-income countries) community-based and/or hospital settings. Each phase of the review will be conducted by two independent reviewers and a third reviewer will resolve conflicts. We will use the JBI Data Extraction Form for Review for Systematic Reviews and Research Syntheses to conduct data extraction of the selected studies. For each intervention of interest, an assessment of the quality of evidence will be performed with the Grading of Recommendations Assessment, Development, and Evaluation (GRADE). Findings will be disseminated via a peer-reviewed publication and useful in regard of a research project in collaboration with Geneva’s University Hospital on children’s psychosocial hospitalization.
Discussion The findings of our umbrella review will facilitate the access of healthcare and social workers to effective interventions promoting health literacy among children and their families, preventing child negligence and psychosocial hospitalization.
Systematic review registration This protocol was registered with the International Prospective Register of Systematic Reviews (PROSPERO) on December 15, 2022 (registration number: CRD42022384377).
Measured Oxygen Consumption During Pediatric Cardiac Catheterization is More Accurate Than Assumed Oxygen Consumption
Authors: Ralston Bradford H , Waberski Andrew T , Kanter Joshua P , Schick Jacob W , Downing Tacy E 
Published: February 2023

Abstract
Objectives
To validate the measured oxygen consumption (VO2) from the CARESCAPE E-sCAiOVX module in the pediatric catheterization lab, and compare its accuracy with assumed VO2.
Background
Assumed VO2 is a known source of error in the calculation of cardiac index. Using a measured VO2 (mVO2) from the CARESCAPE E-sCAiOVX module has been clinically validated by the reverse Fick method in some populations, but not in a general pediatric catheterization population.
Methods
mVO2 was recorded for all patients undergoing cardiac catheterization with general anesthesia and controlled ventilation during the study period. mVO2 was compared to the reference VO2 (refVO2) determined by the reverse Fick method using cardiac MRI (cMRI) or thermodilution (TD) as a reference standard for measurement of cardiac index.
Results
193 VO2 measurements were obtained, including 71 with a corresponding cMRI or TD measure of cardiac index for validation. mVO2 demonstrated satisfactory concordance and correlation with the TD- or cMRI-derived refVO2 (ρc = 0.73, r2 = 0.63) with a mean bias of -3.2% (SD ± 17.3%). Assumed VO2 demonstrated much weaker concordance and correlation with refVO2 (ρc = 0.28, r2 = 0.31) with a mean bias of + 27.5% (SD ± 30.0%). Subgroup analysis of patients < 36 months of age demonstrated that error in mVO2 was not significantly different from that observed in older patients. Many previously reported prediction models for assuming VO2 performed poorly in this younger age range.
Conclusions
Measured oxygen consumption using the E-sCAiOVX module is significantly more accurate than assumed VO2 when compared to TD- or cMRI-derived VO2 in a pediatric catheterization lab.
Reversible electric-field-induced phase transition in Ca-modified NaNbO3 perovskites for energy storage applications
Authors: Aso Seiyu , Matsuo Hiroki , Noguchi Yuji 
Published: February 2023

Abstract
Sodium niobate (NaNbO3) is a potential material for lead-free dielectric ceramic capacitors for energy storage applications because of its antipolar ordering. In principle, a reversible phase transition between antiferroelectric (AFE) and ferroelectric (FE) phases can be induced by an application of electric field (E) and provides a large recoverable energy. However, an irreversible phase transition from the AFE to the FE phase usually takes place and an AFE-derived polarization feature, a double polarization (P)-E hysteresis loop, does not appear. In this study, we investigate the impact of chemically induced hydrostatic pressure (pchem) on the phase stability and polarization characteristics of NaNbO3-based ceramics. We reveal that the cell volume of Ca-modified NaNbO3 [(CaxNa1−2xVx)NbO3], where V is A-site vacancy, decreases with increasing x by a positive pchem. Structural analysis using micro-X-ray diffraction measurements shows that a reversible AFE–FE phase transition leads to a double P-E hysteresis loop for the sample with x = 0.10. DFT calculations support that a positive pchem stabilizes the AFE phase even after the electrical poling and provides the reversible phase transition. Our study demonstrates that an application of positive pchem is effective in delivering the double P-E loop in the NaNbO3 system for energy storage applications.
Draft proteome of Colletotrichum falcatum revealed differential abundance of fungal pathogenicity-related proteins during red rot disease in sugarcane
Authors: Gujjar Ranjit Singh , Joshi Deeksha , Srivast Sangeeta , Kumar Rajeev , Singh Shweta , Shiv Aalok , Goswami Sanjay Kumar , Pathak Ashwini Dutt , Viswanathan Rasappa 
Published: February 2023

Abstract
A highly virulent Colletotrichum falcatum pathotype (CF08) was cultured in nutrient deficit media with fine-cut sugarcane stalks of red rot susceptible variety (CoJ 64). The mycelium was collected for the analysis of whole proteome using LCMS/MS. In-silico analysis was performed to identify the exclusive and differentially abundant proteins from whole proteomes of C. falcatum samples cultured with sugarcane (CFS1 and CFS2). Whole proteome analysis revealed a relatively higher number of peptide identities/proteins in CFS2 (2233), followed by CFS1 (1911), and CFC (control) with least number of proteins (1808). Compared to control, CFS1 and CFS2 samples of C. falcatum had plenty of exclusively abundant proteins like ABC transporters, glucose transporter, actin cytoskeleton-regulatory complex proteins, antimicrobial peptides, autophagy-related proteins, chitin synthase, dicer-like proteins, histone-lysine N-methyltransferase proteins, myosin-1 proteins, polyketide synthase proteins, and nonribosomal peptide synthase proteins which are involved in the process of fungal virulence/pathogenicity. In this manuscript, we report the first draft of C. falcatum proteome (whole proteome) which has been successfully submitted to ProteomeXchange Consortium via the PRIDE partner repository with the dataset identifier PXD033368.
Identification and Validation of a Four-Gene Prognostic Signature Based on PPAR Signaling Pathway for Oral Squamous Cell Carcinoma
Authors: WU Siyuan , LV Xiaozhi , WU Jialin , WEI Haigang , LIU Shiwei , ZOU Chen , SONG Jing , LI Xia , AI Yilong 
Published: February 2023

Abstract
This study aims to create a novel prognosis-related risk signature for oral squamous cell carcinoma (OSCC) based on the PPAR signaling pathway. TCGA and GEO data were respectively evaluated and verified. For the purpose of identifying OSCC prognostic genes, LASSO regression, univariate Cox, and multivariate Cox analyses were conducted. The predictive characteristic of OSCC was determined to be a combination of four genes (ACAA1, PCK1, APOA2, and OLR1) that were involved in the PPAR signaling pathway. On the basis of the multivariate Cox regression coefficients, the risk score was established, which was equal to (-0.378×ACAA1 value)+(1.023×PCK1 value)+(0.301×APOA2 value)+(0.142×OLR1 value). Kaplan-Meier survival analysis demonstrated that risk score had strong prognostic capability in both TCGA dataset and GEO dataset. Moreover, we constructed a nomogram utilizing clinical factors and risk score to estimate the likelihood of OSCC patient survival. In addition, the patterns of cellular immune infiltration in the tumor samples varied considerably between groups with different risk scores. In conclusion, the four-gene signature could accurately and independently predict OSCC prognosis. These genes may possibly be therapeutic targets for OSCC and bring new insights into the prognosis of OSCC.
Affine Periodic Solutions for Stochastic Differential Equations with exponential dichotomy
Authors: Guo Ruichao , Wang Hongren 
Published: February 2023

Abstract
In this paper, we are dedicated to studying the problem of affine periodicity of solutions in distribution for stochastic differential equation with exponential dichotomy. We prove the existence and uniqueness of stochastic affine periodic solutions in distribution via Banach fixed point theorem.
Longitudinal changes in resilience mediate the relationship between child maltreatment and emotional-behavioral problems in an early adolescent cohort
Authors: WANG SJ , Cao Leilei , Li Yuan , Li Yonghan , Yuan Mengyuan , Chang Junjie , Zhang Xueying , Wang Gengfu , Su Puyu 
Published: February 2023

Abstract
Emotional and behavioral problems (EBPs) are serious social problems prevalent among children and adolescents. However, additional information is needed to understand if resilience changes could mediate the association between child maltreatment and EBPs. Our study group conducted a cohort study among 1605 early adolescent students in grades 7 to 9 to answer these questions. The results revealed that resilience changes could partially mediate the association between child maltreatment and emotional problems, conduct problems, hyperactivity-attention, and peer problems during early adolescence. Further, changes in resilience could completely mediate the association between child maltreatment and prosocial behaviors. The resilience of adolescents is slightly improved during early adolescence. Resilience changes can mediate child maltreatment and EBPs, implying that maltreatment during childhood could hinder the development of resilience during early adolescence. Together, this could lead to the development of severe EBPs. Therefore, supporting the establishment of internal and providing external resilience resources could help prevent EBPs during early adolescence.
Renal histopathological indices for predicting the progression to end-stage kidney disease in patients with antineutrophil cytoplasmic antibody-associated vasculitis and glomerulonephritis: a single-centre study in Korea
Authors: Choi Sung-Eun , Lee Soo Bin , Pyo Jung Yoon , Ahn Sung Soo , Song Jason Jungsik , Park Yong-Beom , Lim Beom Jin , Lee Sang-Won 
Published: February 2023

AbstractObjective This study investigated whether histopathological classification and histologic lesion scores could significantly and independently predict the progression to end-stage kidney disease (ESKD) in Korean patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis-glomerulonephritis (AAV-GN). Methods This study included 113 patients with AAV-GN confirmed by kidney biopsy. The glomerular, tubulointerstitial, and vascular lesions were systematically assessed using a scoring system. The scoring system was adopted from the Banff scoring system but also the Oxford study and the revision of the ISN/RPS. For comparison, the scores were classified into two groups; the low, and the high, and the difference was investigated between ESKD and non-ESKD groups using Cox proportional analysis. Results At diagnosis, the median age was 59.0 years and 33.6% were male. Of 113 patients, 44.2% showed ESKD progression during follow-up. There were significant differences in several kidney-, inflammation-, and AAV-pathogenesis-related variables between AAV-GN patients with ESKD and those without. The sclerotic class exhibited the worst renal prognosis among the four histopathological classes. Among histopathological features, high interstitial fibrosis, tubular atrophy and global glomerulitis scores were significantly associated with ESKD progression. Whereas multivariable Cox analysis revealed only a high global glomerulitis score which means global endocapillary hypercellularity in a larger number of glomeruli is an independent predictor of ESKD progression. Moreover, among clinical and histopathological features, a high global glomerulitis score could also predict ESKD progression in addition to serum blood urea nitrogen and creatinine. Conclusion This study demonstrated the worst renal prognosis for the sclerotic class and first discovered that a high global glomerulitis score was an independent predictor of ESKD in patients with AAV-GN.
Analysis of the magneto-thermoelastic vibrations of rotating Euler- Bernoulli nanobeams using the nonlocal elasticity model
Authors: Abouelregal Ahmed E. , Marin Marin , Askar Sameh S. 
Published: February 2023

Abstract
This paper introduces size-dependent modeling and investigation of the transverse vibrational behavior of rotating thermoelastic nanobeams by means of nonlocal elasticity theory. In the formulation, a model of thermal conductivity with two-phase delays (DPL) was utilized. By incorporating the interactions between phonons and electrons, this model took into account microstructural influences. Also, we have employed the state-space approach and Laplace transform approach to solve the governing equations, which were developed in the context of the nonlocal Eringen model. The nanobeam material is subjected to a changeable temperature field produced by the graphene tape attached to the nanobeam and connected to an electrical source. In addition, the nanobeam material is fully encompassed by an axially applied magnetic field. It has been revealed how coefficients such as the rotational angular velocity of the nanobeam, nonlocal coefficient, voltage, electrical resistance, and applied magnetic field influence its behavior.
Isolation and genomic characterization of a reassortant G9P[8]-E2 rotavirus strain in China
Authors: Peng Rui , Li Dan-di , Wang Jin-dong , Xiong Guang-ping , Wang Meng-xuan , Liu Dan , Wei Yu-hang , Pang Li-li , Sun Xiao-man , Li Hui-ying , Kong Xiang-yu , Shahar Saleha , Duan Zhao-jun 
Published: February 2023

Abstract

Objective: To isolate a prevalent G9P[8] group A rotavirus (RVA) strain (N4006) in China and investigate its genomic and evolutionary characteristics, with the goal of facilitating the development of a new rotavirus vaccine.
Methods: An RVA strain of the G9P[8] genotype from a diarrhea sample was passaged in MA104 cells. The strain was evaluated by SEM, polyacrylamide gel electrophoresis, and indirect immunofluorescence assay. The complete genome of the strain was obtained by RT-PCR and sequencing. The genomic and evolutionary characteristics of the strain were evaluated by nucleic acid sequence analysis with MEGA ver. 5.0.5 and DNASTAR software. The neutralizing epitopes of VP7 and VP4 (VP5* and VP8*) were analyzed using BioEdit ver. 7.0.9.0 and PyMOL ver. 2.5.2.
Results: The N4006 strain (G9P[8] genotype) was adapted in MA104 cells with a high titer (105.5 PFU/mL). Whole-genome sequence analysis showed N4006 to be a reassortant rotavirus of Wa-like G9P[8] RVA and the NSP4 gene of DS-1-like G2P[4] RVA, with the genotype constellation G9-P[8]-I1-R1-C1-M1-A1-N1-T1-E2-H1 (G9P[8]-E2). Phylogenetic analysis indicated that N4006 had a common ancestor with Japanese G9P[8]-E2 rotavirus strains. Neutralizing epitope analysis showed that VP7, VP5*, and VP8* of N4006 had low homology with vaccine strains of the same genotype and marked differences with vaccine strains of other genotypes.
Conclusion: The G9P[8] genotype rotavirus with the G9-P[8]-I1-R1-C1-M1-A1-N1-T1-E2-H1 (G9P[8]-E2) constellation predominates in China and may originate from reassortment between Japanese G9P[8] with Japanese DS-1-like G2P[4] rotaviruses. The antigenic variation of N4006 with the vaccine strain necessitates evaluation of the effect of the rotavirus vaccine on G9P[8]-E2 genotype rotavirus.
Application of Remote sensing and GIS on studying the impact of « Jasmin revolution » on Mellegue catchment
Authors: Weslati Okba , Serbaji Mohamed Moncef 
Published: February 2023

Abstract

“Jasmin revolution” is a Tunisian revolt occurred in 2011 referring to the first uprising that unleashed similar events in Middle East and North-Africa called “Arab Spring”. This revolution has led to series of political actions where the government has passed through consecutives bumps that caused socio-political insecurity and environmental damage. The watershed of Mellegue is a cross-border basin belonging to Algeria and Tunisia. It is a vast catchment occupying more than 10500 km². This paper aimed to study the post-revolution impacts on the watershed Mellegue using geospatial data, remote sensing and GIS. It highlights that the resources were significantly consumed. Remote sensing analysis showed that forests were reduced due to anthropogenic activities. Water quantification revealed an over-consumption of these resources where the consumption rate was intensified after 2011 revolution. Population census using geospatial data and modelling approach exhibits a total increase in demography of the study area but also exposes an antagonist behaviour in Algerian territory compared to the Tunisian lands of the catchment. The Algerian demography are in consistent rise unlike Tunisian population that showed a stable to even decline in population growth.
Classification and Analysis of Cyberattacks in the Western Balkans Countries - with a focus on the treatment of policy violations and strategies that states use to protect against attacks
Authors: Mollakuqe Elissa , Dimitrova Vesna 
Published: February 2023

Abstract
Rapid technological developments have also affected the countries of the Balkans, where as a result many hackers and other attackers have attempted to attack computer systems and data in these countries as well. The initial attacks that directed you to these places were "phishing" attacks where there was an attempt to suspend the work of online systems, especially in Public Institutions. But over time, especially in the last 3 years, the biggest attacks belong to DDoS attacks, which have caused many problematic situations and an instability of the systems in these countries. Cyber ​​attacks are normal in the era we live in now, but the reasons for these attacks still vary from the most diverse, such as: political blackmail, blackmail of other kinds or even blackmail for monetary benefits. Our research considers 7 countries of the Balkans: Kosovo, North Macedonia, Albania, Serbia, Montenegro, Bosnia and Herzergovina, and Croatia. The main analysis focuses on the treatment of policies to protect against cyber attacks and strategies that these countries have with the aim of protecting against cyber attacks, which were on a large scale during the last period. All data has been collected during real time and the countries are ranked according to the level of exposure to the risk. The purpose of this research is to know the current situation in the Balkans and to identify the types of attacks directed at these countries, also some investigations into the current strategies have been proposed. The paper uses methods of analysis and synthesis, comparative methods, as well.
Co-planning and co-design as progress in the implementation of welfare services
Authors: Becchetti Leonardo , PIsani Fabio , Raffaele Luca 
Published: February 2023

Abstract
Co-planning (and co-design) of welfare services between public administrations and civic organisations is an innovative approach aiming to enact and maximise aggregate effort and competence contributions among complementary actors in the direction of participation and active citizenship. In our paper we develop a simple theoretical framework trying to illustrate how it is possible to pursue the first best of an optimal participated planning, design and management approach for welfare services. We examine pros and cons of different solutions reconciling involvement of civil actors and respect of antitrust principles outlining four benchmark models with different characteristics in terms of upstream and downstream participation levels. We outline policy proposals to solve dilemmas related to the difficulty of jointly activating participation, intrinsic and monetary incentives avoiding in the meanwhile collusion and corruption.
JEL numbers: I38, I30.
Prenatal diagnosis of Down syndrome combined with transient abnormal myelopoiesis in foetuses with a GATA1 gene variant: Two case reports
Authors: HUI TANG , HU JINGJING , Liu Ling , Lv Lijuan , Lu Jian , Yang Jiexia , Lu Jiaqi , Chen Zhenhui , Yang Chaoxiang , Chen Dan , Fu Jintao , Wu Jing 
Published: February 2023

Abstract
Background

Transient abnormal myelopoiesis (TAM) is a transient haematological disorder of Down syndrome that is characterised by leucocytosis, the presence of blasts, abnormal haematopoiesis and hepatosplenomegaly. It is usually diagnosed within 8 weeks of birth, and the median age of diagnosis is 3–7 days.

Case presentation

We report two cases of prenatally diagnosed TAM, both with male foetal onset. One case was a rare placental low percentage 21 trisomy mosiacism, resulting in the occurrence of a false negative NIPT. The final diagnosis was made at 36 weeks of gestation when ultrasound revealed significant enlargement of the foetal liver and spleen and an enlarged heart; the foetus eventually died in utero. We detected a placenta with a low percentage (5%-8%) of trisomy 21 mosiacism by CNV-seq and FISH. In another case, foetal oedema was detected by ultrasound at 31 weeks of gestation. Two foetuses were diagnosed with Down syndrome by chromosomal microarray analysis (CMA) via umbilical vein puncture and had significantly elevated cord blood leucocyte counts with large numbers of blasts. The GATA1 Sanger sequencing results suggested the presence of a [NM_002049.4(GATA1):c.220G > A (p. Val74Ile)] hemizygous variant and a [NM_002049.4(GATA1):c.49dupC(p. Gln17ProfsTer23)] hemizygous variant of the GATA1 gene in two cases.

Conclusion

It seems highly likely that these two identified mutations are the genetic cause of prenatal TAM in foetuses with Down syndrome.