bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis of a new Cd (II) complex as ionophores and its application in construction of a highly selective and sensitive cadmium (II) sensor in petroleum water samples
Authors: Mohammed Mahdi A. , Fetoh Ahmed , Youssef Magdy M. , Abu El‐Reash Gaber M. , El‐Reash Y. G. Abou , Ali Tamer Awad 
Published: June 2023

The measurement of Cd (II) ions in various matrices requires the development of sensors that are selective, sensitive, and simple to produce. The cadmium complex of a ligand prepared by the reaction of 2‐pyridinecarbohydrazide with sodium 3‐formyl‐4‐hydroxybenzenesulfonate, [Cd (NaPH)(H2O)].H2O, was synthesized, analyzed by elemental analysis, and structurally elucidated using various spectroscopic techniques. The infrared spectrum of Cd (II) complex suggests a bi‐negative tri‐dentate ONO behavior for the ligand via deprotonated form of both the enolic oxygen atom (C‐O−) and the hydroxyl group of phenolic ring in addition to the azomethine group. The thermal behavior of this complex was revealed using TGA analysis. Applying Coast–Redfern and Horowitz–Metzger equations, we were able to calculate the kinetic and thermodynamic parameters to support the proposed fragmentation experiment for the Cd (II) complex. Cyclic voltammetry measurement was measured to estimate the electrochemical behavior of the Cd (II) ions as well as the impact of adding various NaH2PH ligand concentrations. The biological applications of [Cd (NaPH)(H2O)].H2O complex were assessed as antioxidant, anticancer, and antimicrobial. Based on the Cd (II) complex, we were able to modify Cd (II) ions carbon paste electrode (modified carbon paste electrode, MCPE) as a Cd (II) selective modifier. The created electrode displays a Nernstian slope in the linear range of 0.0001 to 10 mmol/L of 29.16 ± 0.03 mV decade−1, a quick reaction time of 6 s, and pH independence from 3–7. The suggested MCPE demonstrated strong selectivity to Cd (II) ions relative to many other cations and displayed negligible change in the slope or operating range if the experiment was achieved in a partially non‐aqueous solution. This fabricated MCPE was used to determine Cd (II) ions in diverse water samples.
Biodegradable waterborne polyurethane‐urea dispersion adhesives with high biocontent
Authors: Patel Amal , Rajput Bhausaheb S. , Hai Thien An Phung , Zhen Daniel , Gunawan Natasha R. , Tessman Marissa , Reindel Jaysen , Shepherd Jenna , Simkovsky Ryan , Pomeroy Robert S. , Pourahmady Naser , Mayfield Stephen P. , Burkart Michael D. 
Published: June 2023

AbstractNon‐biodegradable petroleum‐based plastic wastes have become a leading environmental concern, and new efforts are underway to prepare biobased and biodegradable replacements. We have explored the preparation of adhesives suitable for use in consumer products, and here we report the development of waterborne, biodegradable adhesives from biobased monomers resulting in adhesives exceeding 70% biocontent. Using water as the polymer medium, viscosity challenges and the use of volatile organic solvents are avoided. Material properties of the polyurethane dispersions, resulting films, and laminates produced showed Mw ranging between 56,000 and 124,000. Lastly, the biodegradability of films and laminates was evaluated. The resulting metrics indicate that the adhesives produced meet the desired mechanical and biodegradability targets, indicating that high renewability content solvent‐free polyurethane dispersions are a viable solution for lamination adhesives.
A Piperazine Linked Rhodamine‐BODIPY FRET‐based Fluorescent Sensor for Highly Selective Pd2+ and Biothiol Detection
Authors: Tang Fung‐Kit , Chen Yanyan , Nnaemaka Tritton Daniel , Cai Zongwei , Cham‐Fai Leung Ken 
Published: June 2023

AbstractA class of rhodamine‐based fluorescent sensors for the selective and sensitive detection of Pd2+ metal ions in aqueous media has been developed. A rhodamine‐based sensor PMS and a rhodamine‐BODIPY Förster resonance energy transfer (FRET)‐pair sensor PRS have been incorporated with a piperazine linker and an O−N−S−N podand ligand for specific recognition of Pd2+ ion. Both probes displayed colorimetric and fluorescent ratiometric changes when exposed to Pd2+, due to their spirolactam rings opening and restoring rhodamine conjugation. PRS is highly selective to Pd2+ over 22 other metal ions, showing a 0.6‐fold ratiometric difference at I600nm/I515nm. Additionally, the lactam ring in Pd2+ coordinated PRS‐Pd could be switched back to the closed form in the presence of various thiols, providing a “red‐green traffic light” detection mechanism between red and green emission. Furthermore, PRS showed excellent cell viability and was successfully employed to image Pd2+ and the PRS‐Pd complex ensemble could interchangeably detect biothiols including glutathione (GSH) in A549 human lung cancer cells.
PCNL in neurogenic bladder: A challenging population for both clinical management and analysis
Authors: Heijkoop Bridget , Chislett Bodie , Perera Marlon , Esler Stephen , Bolton Damien , Webb David Rowan 
Published: June 2023

AbstractObjectivesTo review the management of patients with neurogenic bladder undergoing percutaneous nephrolithotomy (PCNL) at our institution with the aim of assessing peri‐operative morbidity.Subjects/patients and methodsWe conducted a retrospective review of all neurogenic bladder patients who underwent PCNL at our hospital in the last decade with the aim of assessing peri‐operative morbidity.ResultsA total of 298 PCNL were performed during the study period of which 58 were in patients with a neurogenic bladder or urinary diversion, 33 of which were in SCI patients. Preoperative demographic and stone characteristics, intraoperative data and postoperative length of stay and complications are summarised in table form.ConclusionPCNL remains an acceptably safe and efficacious treatment for upper tract stone disease in patients with neurogenic bladders and will continue to have a valuable role where SCI prevents alternative approaches such as ureteroscopy.
Surgical outcomes following encephaloduroarteriosynangiosis in moyamoya disease associated with hyperhomocysteinemia
Authors: Gao Gan , Hao Fang‐bin , Wang Qian‐Nan , Wang Xiao‐Peng , Liu Si‐meng , Wang Min‐jie , Guo Qing‐bao , Li Jing‐jie , Bao Xiang‐Yang , Han Cong , Duan Lian 
Published: June 2023

AbstractIntroductionThis study investigated the effect of indirect revascularization surgery in adult patients with moyamoya disease (MMD) complicated with hyperhomocysteinemia (HHcy), and the effect of HHcy on the progression of adult MMD.MethodsA retrospective case‐control study was conducted in patients with MMD, with or without HHcy (n = 123). Postoperative collateral angiogenesis was evaluated using the Matsushima grading system and disease progression using the Suzuki staging system. Cerebral blood flow was evaluated before and after surgery using dynamic susceptibility contrast magnetic resonance imaging (DSC‐MRI) and neurological function prognosis using the improved Rankin score (mRS). Univariate and multivariate logistic regression analyses were performed to determine risk factors for the clinical outcomes.ResultsThere was no significant difference in the Suzuki stage composition ratios between the HHcy group and the non‐HHcy group before and after surgery. Non‐HHcy patients were more likely to grow new collateral circulating vessels after encephaloduroarteriosynangiosis (EDAS). Moreover, postoperative DSC‐MRI indicated that the time to peak significantly improved.ConclusionsHHcy level may be a specific predictor of adverse clinical outcomes after EDAS in patients with MMD and a risk factor for poor collateral circulation and poor prognosis. Patients with MMD complicated with HHcy need to strictly control homocysteine levels before EDAS surgery.
USP51/PD‐L1/ITGB1‐deployed juxtacrine interaction plays a cell‐intrinsic role in promoting chemoresistant phenotypes in non‐small cell lung cancer
Authors: Li Jianjun , Xiao Xuechun , Ou Yang , Cao Lixia , Guo Min , Qi Chunchun , Wang Zhaoyang , Liu Yuxin , Shuai Qiuying , Wang Hang , Sun Peiqing , Shi Yi , Yang Guang , Yang Shuang 
Published: June 2023

AbstractBackgroundProgrammed death ligand 1 (PD‐L1) has been demonstrated to facilitate tumor progression and therapeutic resistance in an immune‐independent manner. Nevertheless, the function and underlying signaling network(s) of cancer cell‐intrinsic PD‐L1 action remain largely unknown. Herein, we sought to better understand how ubiquitin‐specific peptidase 51 (USP51)/PD‐L1/integrin beta‐1 (ITGB1) signaling performs a cell‐intrinsic role in mediating chemotherapeutic resistance in non‐small cell lung cancer (NSCLC).MethodsWestern blotting and flow cytometry were employed for PD‐L1 detection in NSCLC cell lines. Coimmunoprecipitation and pulldown analyses, protein deubiquitination assay, tissue microarray, bioinformatic analysis and molecular biology methods were then used to determine the significance of PD‐L1 in NSCLC chemoresistance and associated signaling pathways in several different cell lines, mouse models and patient tissue samples. Ubiquitin‐7‐amido‐4‐methylcoumarin (Ub‐AMC)‐based deubiquitinase activity, cellular thermal shift and surface plasmon resonance (SPR) analyses were performed to investigate the activity of USP51 inhibitors.ResultsWe provided evidence that cancer cell‐intrinsic PD‐L1 conferred the development of chemoresistance by directly binding to its membrane‐bound receptor ITGB1 in NSCLC. At the molecular level, PD‐L1/ITGB1 interaction subsequently activated the nuclear factor‐kappa B (NF‐κB) axis to elicit poor response to chemotherapy. We further determined USP51 as a bona fide deubiquitinase that targeted the deubiquitination and stabilization of the PD‐L1 protein in chemoresistant NSCLC cells. Clinically, we found a significant direct relationship between the USP51, PD‐L1 and ITGB1 contents in NSCLC patients with chemoresistant potency. The elevated USP51, PD‐L1 and ITGB1 levels were strongly associated with worse patient prognosis. Of note, we identified that a flavonoid compound dihydromyricetin (DHM) acted as a potential USP51 inhibitor and rendered NSCLC cells more sensitive to chemotherapy by targeting USP51‐dependent PD‐L1 ubiquitination and degradation in vitro and in vivo.ConclusionsTogether, our results demonstrated that the USP51/PD‐L1/ITGB1 network potentially contributes to the malignant progression and therapeutic resistance in NSCLC. This knowledge is beneficial to the future design of advanced cancer therapy.
Molecular typing and mutational characterization of rectal neuroendocrine neoplasms
Authors: Duan Xiaoling , Zhao Man , Yin Xiaolei , Mi Lili , Shi Jianfei , Li Ning , Han Xin , Han Guangjie , Wang Jinfeng , Hou Jiaojiao , Yin Fei 
Published: June 2023

AbstractBackgroundRectal neuroendocrine neoplasms (NENs) are rare neoplasms with limited understanding of its genomic alterations and molecular typing.MethodsThe paraffin‐embedded tissue specimens of 38 patients with rectal NENs after surgery were subjected to whole gene sequencing (WGS), and mutation profilings were drawn to identify high‐frequency mutation genes, copy‐number variations (CNVs), tumor mutation burden (TMB), signal pathways, mutation signatures, DNA damage repair (DDR) genes, and molecular types. The differences of mutated genes and signaling pathways in different pathological grades and metastatic/non‐metastatic groups were compared. It helped to search for potential targets.ResultsC > T and T > C transitions are the most common base substitutions in rectal NENs. DNA mismatch repair deficiency, DNA base modifications, smoking and exposure to ultraviolet light might play a role in the occurrence of rectal NENs. DAXX, KMT2C, BCL2L1, LTK, MERTK, SPEN, PKN1, FAT3, and LRP2 mutations were found in only low‐grade rectal NETs, whereas APC, TP53, NF1, SOX9, and BRCA1 mutations were common in high‐grade rectal NECs/MiNENs. These genes helped in distinguishing poorly‐differentiated or well‐differentiated rectal NENs. Alterations in P53, Wnt and TGFβ signaling pathways were more pronounced in rectal NECs and MiNENs. Alterations in Wnt, MAPK and PI3K/AKT signaling pathways promoted metastases. Rectal NENs were classified into two molecular subtypes by cluster analysis based on the mutant genes and signaling pathways combined with clinicopathological features. Patients with mutations in the LRP2, DAXX, and PKN1 gene showed a trend of well‐differentiated and early‐stage tumors with less metastasis (p = 0.000).ConclusionsThis study evaluated risk factors for regional lymphatic and/or distant metastases, identified high‐frequency mutated genes, mutation signatures, altered signaling pathways through NGS. Rectal NENs were divided into two molecular types. This helps to evaluate the likelihood of metastasis, formulate follow‐up strategies for patients and provide a target for future research on precision treatment of rectal NENs. PARP inhibitors, MEK inhibitors, mTOR/AKT/PI3K and Wnt signaling pathway inhibitors may be effective drugs for the treatment of metastatic rectal NENs.
Flexible Self‐Powered Energy Systems Based on H2O/Ni2+ Intercalated NixV2O5 ⋅ nH2O
Authors: Zhu Zhenfu , Liang Xiaoyuan , Luo Haoyu , Wang Liying , Gao Yang , Li Xuesong , Yang Xijia , Lü Wei 
Published: June 2023

AbstractThe development of portable electronic devices has created greater demands for multifunctional energy integration systems. Self‐powered systems have gained widespread interest because they can collect and storage renewable environmental energy and provide stable electricity to electronic devices. Herein, we developed a flexible self‐charging energy system, involving textile‐based zinc‐ion hybrid (ZIHC) and triboelectric nanogenerator (TENG), which demonstrates wearable, compatibility, lightweight and can quickly harvest and store energy. NixV2O5 ⋅ nH2O (NVO) loaded on carbon cloth (CC) with Ni2+/H2O ions intercalated as the cathode was assembled with activated CC to form a ZIHC, which has a voltage range of 2.0 V and capacitance value of 267.1 mF cm−2 as well as good charge and discharge rates and excellent cycling stability. At the same time, the NVO/CC can be assembled with PDMS to form a TENG achieving a maximum instantaneous power of 18.5 mW cm−2. The device can be flexibly worn over the body to continuously harvest and store biomechanical energy and charge the electronic wristwatch successfully. This work demonstrates great convenience and promising practical applications as sustainable flexible energy system for portable electronic devices.
PtCo/MWCNTs Prepared by a Microwave‐assisted Polyol Method for Selective Cinnamaldehyde Hydrogenation
Authors: Wang Kaiying , Liu Yuzi , Wang Jee‐Ching , Liang Xinhua 
Published: June 2023

AbstractUsing microwave irradiation, PtCo alloy nanoparticles were deposited within a few minutes on COOH‐functionalized MWCNT supports. The obtained catalysts were used for selective hydrogenation of cinnamaldehyde, a reaction whose products are widely used in various fields. In the selective cinnamaldehyde hydrogenation to cinnamyl alcohol, microwave‐prepared catalysts (generically, PtxCoy‐MW) outperformed a catalyst prepared by the conventional method (Pt1Co2‐con). The highest selective hydrogenation to cinnamyl alcohol, 89%, was obtained using Pt1Co2‐MW, while Pt1Co2‐con showed a selectivity of 76%. Characterization results confirmed that the microwave prepared samples had a stronger interaction between Pt and Co than that in the Pt1Co2‐con sample. The alloyed Co altered the electronic structure of Pt, leading to favorable adsorption of the C=O bond by the lone‐pair electrons of its oxygen atom. Moreover, the Pt1Co2‐MW sample showed neglectable change in catalytic performance (e. g., cinnamaldehyde conversion and selective hydrogenation to cinnamyl alcohol) during recycling experiments.
Predicting Degradation Mechanisms in Lithium Bistriflimide “Water‐In‐Salt” Electrolytes For Aqueous Batteries
Authors: Paillot Malaurie , Wong Alan , Denisov Sergey A. , Soudan Patrick , Poizot Philippe , Montigny Benedicte , Mostafavi Mehran , Gauthier Magali , Le Caër Sophie 
Published: June 2023

AbstractAqueous solutions are crucial to most domains in biology and chemistry, including in energy fields such as catalysis and batteries. Water‐in‐salt electrolytes (WISEs), which extend the stability of aqueous electrolytes in rechargeable batteries, are one example. While the hype for WISEs is huge, commercial WISE‐based rechargeable batteries are still far from reality, and there remain several fundamental knowledge gaps such as those related to their long‐term reactivity and stability. Here, we propose a comprehensive approach to accelerating the study of WISE reactivity by using radiolysis to exacerbate the degradation mechanisms of concentrated LiTFSI‐based aqueous solutions. We find that the nature of the degradation species depends strongly on the molality of the electrolye, with degradation routes driven by the water or the anion at low or high molalities, respectively. The main aging products are consistent with those observed by electrochemical cycling, yet radiolysis also reveals minor degradation species, providing a unique glimpse of the long‐term (un)stability of these electrolytes.
Accounting for central place foraging constraints in habitat selection studies
Authors: Benhamou Simon , Courbin Nicolas 
Published: June 2023

AbstractHabitat selection studies contrast actual space use with the expected use under the null hypothesis of no selection (hereafter neutral use). Neutral use is most often equated to the relative frequencies with which environmental features occur. This generates a considerable bias when studying habitat selection by foragers that perform numerous trips back and forth to a central place (CP). Indeed, the increased space use close to the CP with respect to distant places reflects a mechanical effect, rather than a true selection for the closest habitats. Yet, correctly estimating habitat selection by CP foragers is of paramount importance for a better understanding of their ecology and to properly plan conservation actions. We show that including the distance to the CP as a covariate in unconditional Resource Selection Functions, as applied in several studies, is ineffective to correct for the bias. This bias can be eliminated only by contrasting the actual use to an appropriate neutral use that considers the CP forager behavior. We also show that the need to specify an appropriate neutral use overall distribution can be bypassed by relying on a conditional approach, where the neutral use is assessed locally regardless of the distance to the CP.
Variable selection for classification and forecasting of the family firm's socioemotional wealth
Authors: Álvarez‐Díez Susana , Baixauli‐Soler J. Samuel , Belda‐Ruiz María , Sánchez‐Marín Gregorio 
Published: June 2023

AbstractSocioemotional wealth (SEW) refers to those family‐centered goals that are likely to have a major influence on the strategic decision‐making process and performance of family firms. Many studies have used indirect indicators related to family involvement in ownership and management to measure SEW; meanwhile, others have developed scales to directly measure the level and importance of SEW in family firms. Limitations of both indirect and direct measures of SEW lead empirical research on SEW to be under threat. In the current study, we use random forests to identify the important indicators related to financial and economic decisions, as well as family‐related measures, for explaining the family firms' SEW and to design a good prediction model using the smallest set of nonredundant indicators. Our results show that the model that exhibits the minimum out‐of‐bag sample (OOB) error rate includes variables that refer to the presence of family members in the firm's management positions, long‐term nonfinancial debt, personnel expenditures, long‐term financial investments, short‐term financial debt, average storage period, and accounts receivables. For prediction, the model with a reasonably low estimated classification error includes only three variables, which refer to the presence of family members in the firm's management positions, long‐term nonfinancial debt, and accounts receivables.
Pricing of American Parisian option as executive option based on the least‐squares Monte Carlo approach
Authors: Zhuang Yangyang , Tang Pan 
Published: June 2023

AbstractIn this study, we create a novel American double‐barrier Parisian call option contract that may be utilized as an executive option for listed companies to incentivize staff and replace the classic American option. We address the option pricing problem by developing state variables to identify the price state and using the least‐squares Monte Carlo approach. We present several Lévy processes to simulate the movement path of the underlying asset. We discover that geometric Brownian motion and normal inverse Gaussian (NIG) process have successful outcomes, and NIG process has greater calculation accuracy than variance gamma process. The barrier width and window length are positively connected with the price of an American Parisian option, whereas the strike price is negatively correlated with it. Increasing the number of discrete periods of the contract will enhance the pricing accuracy.
Electrochemical Organic Synthesis in Aqueous Media
Authors: Li MengFan , Cheng Xu 
Published: June 2023

AbstractConducting electrochemical organic synthesis in/on whole water media is undoubtedly a highly green approach, which avoids the usage of organic solvents, and sometimes organic supporting electrolytes. In this review, the electrochemical organic syntheses in/on whole water environment are reviewed, especially including the reactions conducted both in organic solvent and water for comparisons. This review discussed anodic and cathodic reaction, respectively, including the C−H oxidation, hydroxylation, dehydrogenative cross coupling, functionalization of alkenes, cathodic oxidation, hydrogenation, reductive cross coupling, and so on. As the reduction of CO2, conversion biomass, and waste water disposal are frequently performed in water, and have already been reviewed recently. These topics are not included in this review.
Fabrication of molecularly imprinted resin via controlled polymerization applied in the enrichment of bisphenol A for plastic products
Authors: Wang Haiping , Wang Hongwei , Bai Qingyan , Xu Yunjia , Bo Chunmiao , Gong Bolin 
Published: June 2023

The addition of bisphenol A has been frequently used in industrial manufacturing because it imparts plastic products with characteristics such as transparency, durability, and excellent impact resistance. However, its widespread use raises concerns about potential leakage into the surrounding environment, which poses a significant risk to human health. In this study, molecularly imprinted polymers with specific recognition of bisphenol A were synthesized through surface‐initiated atom transfer radical polymerization using poly(glycidyl methacrylate‐co‐ethylene glycol dimethacrylate) as the substrate, bisphenol A as the template molecule, 4‐vinylpyridine as the monomer, and ethylene glycol dimethacrylate as the cross‐linker. The bisphenol A adsorption capacity was experimentally investigated, and the kinetic analysis of the molecularly imprinted polymers produced an adsorption equilibrium time of 25 min, which is consistent with the pseudo‐second‐order kinetic model. The results of the static adsorption experiments exhibited consistency with the Langmuir adsorption model, revealing a maximum adsorption capacity of 387.2 μmol/g. The analysis of molecularly imprinted polymers‐enriched actual samples using high‐performance liquid chromatography demonstrated excellent selectivity for bisphenol A, with a linear range showing 93.4%–99.7% recovery and 1.1%–6.4% relative standard deviation, demonstrating its high potential for practical bisphenol A detection and enrichment applications.