bluuebunny/crossref_metadata_2025_split huggingface dataset:
La conservación de la naturaleza en las políticas de ordenamiento territorial: estado del arte internacional y situación latinoamericana
Authors: Degele Pamela E. 
Published: July 2023

Los cambios en los usos del suelo aparecen como uno de los impulsores directos del cambio ambiental global. En consecuencia, las recomendaciones internacionales indican la necesidad de integrar las áreas naturales protegidas en las políticas de ordenamiento territorial para favorecer la conservación de la naturaleza, sus valores culturales y servicios ecosistémicos en el largo plazo. Esto es posible al entender que la conservación de la naturaleza es una temática compleja que atraviesa y es atravesada por numerosos asuntos territoriales como la economía, la política y la cultura. Sin embargo, la articulación entre las áreas protegidas y las políticas de ordenamiento territorial constituye aún más un desafío generalizado. En este artículo se expone en qué medida y de qué manera la comunidad científica internacional ha respondido a la necesidad de conocimientos sobre esta temática haciendo foco, particularmente, en el enfoque social de estos procesos. Esta perspectiva es relevante en tanto permite identificar valores, comportamientos sociales y factores políticos para una coordinación eficaz que favorezca la mitigación de la crisis socio-ecológica de “abajo hacia arriba”. Para ello, se presentan los resultados de una revisión sistemática de literatura internacional y, particularmente, latinoamericana, indexada en la base de datos Scopus de los últimos 20 años, complementada con una búsqueda en Scielo y otra bibliografía académica disponible sobre el tema en la región. Se identificaron tres enfoques principales en la literatura, con prevalencia de una visión técnica de la articulación de las áreas protegidas en el ordenamiento territorial, orientada a la medición y predicción de impactos y áreas prioritarias, antes que de análisis de variables políticas y sociales. Se propone una agenda de investigación.
STATISTICAL CONVERGENCE IN A BICOMPLEX VALUED METRIC SPACE
Authors: Bera Subhajit , Tripathy Binod Chandra 
Published: July 2023

In this paper, we study some basic properties of bicomplex numbers. We introduce two different types of partial order relations on bicomplex numbers, discuss bicomplex valued metric spaces with respect to two different partial orders, and compare them. We also define a hyperbolic valued metric space, the density of natural numbers, the statistical convergence, and the statistical Cauchy property of a sequence of bicomplex numbers and investigate some properties in a bicomplex metric space and prove that a bicomplex metric space is complete if and only if two complex metric spaces are complete.
FIXED RATIO POLYNOMIAL TIME APPROXIMATION ALGORITHM FOR THE PRIZE-COLLECTING ASYMMETRIC TRAVELING SALESMAN PROBLEM
Authors: Rizhenko Ksenia , Neznakhina Katherine , Khachay Michael 
Published: July 2023

We develop the first fixed-ratio approximation algorithm for the well-known Prize-Collecting Asymmetric Traveling Salesman Problem, which has numerous valuable applications in operations research. An instance of this problem is given by a complete node- and edge-weighted digraph \(G\). Each node of the graph \(G\) can either be visited by the resulting route or skipped, for some penalty, while the arcs of \(G\) are weighted by non-negative transportation costs that fulfill the triangle inequality constraint. The goal is to find a closed walk that minimizes the total transportation costs augmented by the accumulated penalties. We show that an arbitrary \(\alpha\)-approximation algorithm for the Asymmetric Traveling Salesman Problem induces an \((\alpha+1)\)-approximation for the problem in question. In particular, using the recent \((22+\varepsilon)\)-approximation algorithm of V. Traub and J. Vygen that improves the seminal result of O. Svensson, J. Tarnavski, and L. Végh, we obtain \((23+\varepsilon)\)-approximate solutions for the problem.
Construcción del «Atlas fotográfico de alimentos y bebidas estandarizadas», para apoyo en la aplicación virtual de la encuesta de «24 horas recordatorio método multipasos» y «Rastreador NOVA 27 categorías de UPF»
Authors: Freire Wilma B. , Chávez Andrea Michel , Jiménez Elisa , Blemont Philippe 
Published: July 2023

Objetivo del manual para uso del «Atlas fotográfico de alimentos y bebidas estandarizadas»
Este manual fue elaborado para apoyar a la aplicación virtual de la encuesta de «24 horas recordatorio método multipasos» y del «Rastreador NOVA de 27 categorías de UPF».
Fuentes de información para la construcción del atlas
Para la construcción del Atlas fotográfico de alimentos y bebidas estandarizadas se utilizaron cuatro fuentes de información:

el «Catálogo fotográfico como herramienta para la estimación de la ingesta alimentaria en niños y adultos» elaborado por Chumbi y Vásquez, (1)
el «Atlas fotográfico» del programa Aliméntate Ecuador del Ministerio de Inclusión Económica y Social, (2)fotos de productos ultra procesados sin identificación de origen y
la «Encuesta Nacional de Salud y Nutrición de la Población Ecuatoriana de Cero a 59 Años. ENSANUT 2012», capítulo encuesta de consumo. (3)

El «Catálogo fotográfico» publicado por Chumbi y Vásquez (1) y el «Atlas Fotográfico» publicado por el Aliméntate Ecuador (2) se diseñaron para recolectar información cuantificada del consumo de alimentos con entrevistas cara a cara. En ambos casos, el registro de alimentos se hizo por porciones asignando códigos que diferencian a cada alimento y porción de este, en cuanto al volumen y cantidad en gramos y/o mililitros.
Debido a que el «Catálogo fotográfico» de Chumbi y Vásquez (1) y el Atlas de Aliméntate Ecuador (2) no registran la categoría de productos ultra procesados que son parte de la dieta que consumo de alimentos de la población. Se decidió agregar al Atlas de fotos de alimentos y bebidas ultra procesados, bebidas y alimentos sin identificación de origen. Una vez seleccionadas las fotos de estas tres fuentes, se las agrupó en cinco categorías, 65 subcategoría y 118 porciones.
CONSUMPTION OF MINE WATER BY WILD UNGULATES IN THE SOURCES OF THE USSURI RIVER, ON THE TERRITORY OF THE NATIONAL PARK «CALL OF THE TIGER»
Authors: Panichev Alexander M. , Baranovskaya Natalia V. , Aramilev Vladimir V. , Chekryzhov Igor Yu. , Vakh Еlena А. , Vetoshkina Alena V. , Lutsenko Tatyana N. , Strepetov Dmitry A. 
Published: July 2023

Link for citation: Panichev A.M., Baranovskaya N.V., Aramilev V.V., Chekryzhov I.Yu., Vakh E.A., Vetoshkina A.V., Lutsenko T.N., Strepetov D.A. Consumption of mine water by wild ungulates in the sources of the Ussuri river, on the territory of the national park «Call of the tiger». Bulletin of the Tomsk Polytechnic University. Geo Аssets Engineering, 2023, vol. 334, no. 7, рр. 111-121. In Rus.
The relevance of the study is determined by the need to clarify the reason for the use of mineralized water by wild animals, which is typical for many areas of the world. The new knowledge is closely related to the geophagy problem, the solution of which opens a wide prospect of fundamental research in the fields of landscape biogeochemistry, ecology and medicine. Purpose: to study chemical composition of the mineralized mine water in the lake located on the territory of the out-of-operation tin-polymetallic ores concentrator dump in the upper Ussuri river which is being consumed actively by wild ungulates; to reveal number of animal visitors to the lake during an annual cycle; to reveal the reason of mine water consumption. Objects: ungulates visiting the lake with mine water; lake water and bottom sediments. Methods: estimation of visitation of the mine lake by animals by means of photographic traps; chemical composition determination: inductively coupled plasma mass spectrometry (ICP-MS) (Agilent 7700x spectrometer, Agilent Techn., USA); atomic emission spectrometry (spectrometer iCAP 7600 Duo); ion chromatography (LC-20 ion-liquid chromatograph, Shimadzu, Japan). Results. It was revealed that animals come to the lake uniformly throughout the year, except for the winter period, when the water is covered by a thick layer of ice. In high concentrations trace elements were found, including both elements with high toxicity (Cd and Pb) exceeding MAC for drinking water from 20 to 80 times and essential elements such as Fe, Mn, Cu, Zn, Co, Cr, Ni, Se, Li, which concentration either does not exceed MPC or exceeds it insignificantly. The concentration of REE, especially of the light subgroup, is also very high. The reason for mine water consumption by animals, most likely, is the high concentration of rare-earth elements of the light subgroup in it.
Pengaruh Tata Ruang Kantor terhadap Kinerja Guru di Madrasah Pembangunan
Authors: Yuniarti Dwika , Waruwu Nurdelima , SAM Mu'arif 
Published: July 2023

This study aims to determine the effect of office layout on teacher performance at Madrasah Pembangunan UIN Jakarta. This type of research is quantitative with a linear regression analysis approach. This study uses probability sampling where the population is MP UIN Jakarta teachers. Of the total 165 sample teachers used in this study were 63 teachers from all levels with specifications, 34 MI teachers, 19 MTs teachers, and 10 MA teachers. The research instrument was a questionnaire, document study, and interviews. The questionnaire was used as the main data collection which was distributed to the research subjects, while document study and interviews were used as complementary techniques to obtain data. The research result states that there is a significant influence between the influence of office layout on teacher performance at MP UIN Jakarta. This can be seen from the data processing results of the calculation of SPSS ver 23, through statistical testing of the T-test. The results of the T-test value are 6.140 and T-table is 1.999 with a significance of 0.000. Using the test criteria T-count T-table and if the significance α (0.05), then H0 is rejected, then in the calculation of the coefficient of determination it is known that the effect of office layout on teacher performance at MP UIN Jakarta is 38.2% while the remaining 61.8% is influenced by other factors not examined. However, it can be suggested for a madrasah to pay more attention to the arrangement and area of office space for the freedom of teachers to move. As well as paying attention to what needs are needed by teachers to improve the quality and performance of their teaching.
Análise bibliométrica da temática objetivos de desenvolvimento sustentável (ODS) no campo das ciências sociais aplicadas
Authors: Lima Anderson Antônio , Ribeiro Thiago de Luca Santana 
Published: July 2023

Apesar da relevância da temática e dos impactos dos objetivos de desenvolvimento sustentável em todas as nações, a literatura não apresenta elementos que possibilitem identificar como o fluxo de pesquisa evoluiu ao longo do tempo, entender a evolução das pesquisas sobre a temática podem gerar novos insights e fornecer novas maneiras de implantar objetivos de desenvolvimento sustentável, neste sentido este estudo trata-se de uma análise bibliométrica que visa identificar como o domínio de conhecimento sobre objetivos de desenvolvimento sustentável surgiu e evoluiu no campo de ciências sociais. Trata-se de um estudo revisional, elaborado por meio de uma análise bibliométrica, esta técnica permite o mapeamento do surgimento e evolução de um campo científico, inclusive possibilita identificar os autores mais citados/influentes, instituições dos autores, redes de cooperação entre autores, recorrência de palavras chaves e estudos fronteiriços sobre um determinado tema (Zupic & Cater, 2015). A análise bibliométrica realizada possibilitou identificar por meio do mapa de cocitação a estrutura intelectual que norteia a evolução dos estudos sobre objetivos de desenvolvimento sustentáveis no campo de ciências sociais aplicadas. Esta técnica possibilitou a identificação de sete clusters, o cluster mais importante investigou a interpelação entre os 17 objetivos de desenvolvimento sustentáveis ODS. O mapa de pareamento bibliográfico realizado identificou sete clusters de estudos sobre responsabilidade social corporativa no campo de ciências sociais aplicadas.

Palavras-Chave: Análise Bibliométrica, Objetivos de Desenvolvimento Sustentável; Ciências Sociais Aplicadas
Association of polymorphic variants of <i>CYP2C19</i>, <i>P2RY12</i>, <i>ITGB3</i>, <i>ITGA2</i> and <i>eNOS3</i> genes with high residual platelet reactivity while taking clopidogrel and acetylsalicylic acid at different terms of myocardial infarction
Authors: Pronko T. P. , Snezhitskiy V. A. , Stepuro T. L. , Kapytski A. V. 
Published: July 2023

Aim.Study of the association of polymorphic variants of CYP2C19 (G681A), P2RY12 (H1/H2), ITGB3 (T1565C), ITGA2 (C807T), eNOS3 (T786C) genes with high residual platelet reactivity (HRPR) to clopidogrel and acetylsalicylic acid (ASA) at different terms of myocardial infarction (MI).Material and methods. The study included 400 patients with MI aged 31-74 years, 317 (79,3%) men and 83 (20,7%) women. Platelet aggregation performed on days 1-2, 12-14 and 28-30 of MI, and genotyping by the polymerase chain reaction were analyzed using the STATISTICA 10.0 program.Results.Differences were found in ADP-test 1-3 depending on the CYP2C19 (G681A) polymorphism, ADP-test 1 depending on the P2RY12 (H1/H2) polymorphism, ADP-test 2 depending on the ITGB3 (T1565C) polymorphism, ASPI-test 1 depending on the eNOS (T786C) polymorphism. The risk of HRPR to clopidogrel is higher in 681A CYP2C19 allele carriers compared to the G681 carriers throughout the entire observation period: initially odds ratio (OR) of 1,8 (1,14-2,88), p=0,012, on days 12-14 of MI, OR of 1,7 (1,08-2,68), p=0,023 and on days 28-30 of MI, OR of 2,3 (1,42-3,81), p=0,0008. The risk of HRPR to clopidogrel is higher in AA CYP2C19 genotype carriers compared to GG genotype carriers, on days 1-2 of MI (OR 6,5 (1,16-36,4), p=0,033), on days 28-30 of MI (OR 7,8 (1,26-48,0), p=0,027). The risk of HRPR to clopidogrel on days 1-2 of MI is higher in H2 P2RY12 locus carriers compared to H1 locus carriers (OR 1,5 (1,02-2,22), p=0,039). The risk of HRPR to ASA on days 1-2 of MI is higher in the 786C eNOS3 allele carriers compared to T786 allele carriers (OR 1,4 (1,02-1,96), p=0,036). Carriers of haplotypes of minor alleles of CYP2C19 + ITGA2 + P2RY12 + eNOS genes (OR 3,9 (1,13-13,65), p=0,032) and CYP2C19 + ITGA2 + eNOS genes (OR 5,1 (1,7214,96), p=0,0032) have higher risk of HRPR to dual antiplatelet therapy (DAPT) on days 28-30 of MI compared to the rest of patients.Conclusion.The association of HRPR to clopidogrel with the CYP2C19 (G681A) polymorphism was found during the entire observation period, with the P2RY12 (H1/H2) polymorphism on days 1-2 of MI, with the ITGB3 (T1565C) polymorphism on days 10-12 of MI. The association of HRPR to ASA with eNOS (T786C) polymorphism was found on days 1-2 of MI. Minor allele haplotypes of the CYP2C19 + ITGA2 + P2RY12 + eNOS genes and CYP2C19 + ITGA2 + eNOS genes were associated with a higher risk of developing HRPR to DAPT on days 28-30 of MI.
Management of Bilateral Synchronous Knee Prosthetic Joint Infection in a Patient with Infected Heart Transplant
Authors: Jeong Seongho , Yang Ally , Rubin Lee E. , Arsoy Diren 
Published: July 2023

Case:
A 74-year-old man presented with septic shock with infection of his heart transplant and bilateral prosthetic knee joints simultaneously. He underwent bilateral knee resection arthroplasties with placement of articulating spacers. At 3-year follow-up, the patient was alive and ambulating independently.

Conclusion:
This case represents the first report of bilateral hematogenous prosthetic knee infections associated with concomitant enterococcal endocarditis of a heart transplant treated successfully and definitively with radical debridement and placement of articulating spacer with regular implants.
Factors influencing HPV vaccine implementation in South Asia: A scoping review protocol
Authors: Rajkhowa Priyobrat , Pundir Prachi , Dsouza Sherize Merlin , Patil Divya Sussana , Narayanan Prakash , Brand Helmut 
Published: July 2023

Abstract
Introduction The human papillomavirus vaccine (HPV) is an effective investment in lessening the likelihood of contracting cervical cancer, lower healthcare costs, and reducing disability and death. However, low-income and lower-middle-income nations face multiple challenges in implementing the human papillomavirus vaccine at scale. Implementation of human papillomavirus vaccination for eliminating cervical cancer necessitates investigating the factors that impact the health system of these nations. Hence, this review will map the evidence on factors influencing the scaling up of human papillomavirus vaccination in South Asia. Methods The proposed scoping review will follow the steps given by “Arksey and O'Malley and Levac et al”. The search approach will follow McGowan et al. (2016) 's evidence-based manual for Peer Analysis of Electronic Search Strategies (PRESS 2015) for systematic searches”. Using a comprehensive search, the literature from 2006 onward will be identified from PubMed, CINAHL, EMBASE, Web of Science, and Scopus. The search strategy will include terms relating to the HPV vaccine and implementation. A predefined criterion for the inclusion and exclusion of studies will be adopted by three review authors independently to determine the eligible studies. The results will be narratively synthesized and examined in addition to being quantitatively presented to provide an outline. The review will be presented per the “Preferred Reporting Items for Systematic Reviews and Meta-analyses extension for scoping review (PRISMA-ScR)” guidelines. Conclusions/Discussion The evaluation is anticipated to map the barriers and enablers influencing the rollout of the human papillomavirus vaccine. Lessons learned from the South Asian countries where the vaccine has been implemented may contribute to aiding the implementation of the vaccine in India in an effective manner. Scoping review registration: The protocol was prospectively registered on the “open science framework”. The registration DOI is 10.17605/OSF.IO/QEWG3
Geobody Estimation by Bhattacharyya Method Utilizing Nonlinear Inverse Modeling of Magnetic Data in Baba-Ali Iron Deposit, NW Iran
Authors: Kianoush Pooria , Khah Nasser Keshavarz Faraj , Hosseini Seyed Aliakbar , Jamshidi Emad , Afzal Peyman , Ebrahimabadi Arash 
Published: July 2023

Abstract
One of the essential geophysical concerns is the estimation of the physical and geometrical parameters of the reserve (geobody), which is done by exploiting the nonlinear inverse modeling of magnetic data. The present study includes preparing and modeling magnetic data to suggest drilling sites in the Baba Ali Iron ore deposit, NW Iran. The area is covered with 1000 points of geomagnetic reading with an almost 5×10 m2 regularly spaces grid trending WE. The areal and depth extent of the iron ore geobody was unknown. The Bhattacharyya method by MATLAB software coding was used to minimize the misfit function and re-construct potential field data providing the best fit with measured magnetic data. In this order, the residual calculated anomaly exhibited an excellent two-dimensional conformation with forward modeling. Also, 3D modeling correctly reconstructs properties of the productive resources of anomalies. After preparing full magnetic maps, the magnetic lenses distinguished in four anomalies of surface depths, 20, 50, and deeper than 50 meters for this zone. This magnetite lens for the first zone was estimated based on analytical signal filters applied on the entire magnetic map so that the lens's depth is trivial and almost zero. Due to specific gravity calculated as 4.77 t/m3, initial storage capacity is suggested to be about 95,400 tons of magnetite, pyrite, and hematite minerals at most in an area about 6 Km2. Finally, to complete the preliminary explorations of the specified area, exploratory drilling is suggested for three points by inverse modeling. Regarding this study as the first try in magnetic reconnaissance step of Iron mineral exploration in the study area, there is no geological constraints available based on drilling evidences. However, the model is well satisfies the surface anomalies considering residual magnetic property.
Effect of lactobacillus reuteri-derived probiotic nano-formulation on recurrent aphthous stomatitis: A Double-Blinded Randomized Clinical Trial
Authors: Samiraninezhad Nazafarin , Kazemi Hojat , Rezaee Mostafa , Gholami Ahmad 
Published: July 2023

Abstract
Objectives
We aimed to assess the therapeutic effects of a topical probiotic nano-formulation derived from Lactobacillus reuteri on treating recurrent aphthous stomatitis.
Materials and Methods
60 participants were randomly allocated into two groups (control and probiotic). Probiotic group administered topical probiotic nano-formulation three times a day for seven days. The control group administered a standard analgesic oral rinse. The size of ulcer(s) and pain severity were recorded on days 0, 3, 5, and 7 after intervention.
Results
Before the intervention, the groups had no significant differences in pain severity and lesion size. Both groups reduced pain severity and lesion size during the intervention. After one week, the probiotic group had a significantly larger lesion size reduction (7.41 ± 1.79 mm) than the control (5.94 ± 1.59 mm). The probiotic group also significantly reduced pain severity (6.54 ± 1.56 scores) than the control (5.82 ± 1.66 scores).
Conclusions
Applying topical probiotic nano-formulation derived from Lactobacillus reuteri three times a day decreased lesion size and pain severity in RAS patients faster than the local analgesic oral rinse.
Clinical relevance
: Lactobacillus reuteri-derived probiotic nano-formulation might be a promising treatment option for RAS.
From Pixels to Insights: Unveiling Spatial Immune Associations of Immunotherapy Response in Non-Small Cell Lung Cancer using Multiplexed Tissue Imaging
Authors: Kulasinghe Arutha , Monkman James , Moradi Afshin , Yunis Joseph , Ivison Geoffrey , Mayer Aaron , Ladwa Rahul , O'Byrne Ken 
Published: July 2023

Abstract
Insights into the spatial localisation of immune cells within tumours are key to understand the intercellular communications that dictate clinical outcomes. We applied a tiered approach to characterise the spatial organization and interactions in NSCLC tissues from thirty-five patients that subsequently received PD-1 axis immunotherapy (ICI therapy). Our analysis indicates that regulatory T cells are enriched in non-responding patients. Proximity interactions between Tregs and both monocytes(p=0.009) and CD8+ T cells(p=0.009) were frequently found in non-responding patients, while macrophages were more frequently located in proximity to antigen presenting HLADR+ tumour cells(p=0.01) within responding patients. Spatial compartmentalization of tissues into cellular neighbourhoods indicates that both macrophages(p=0.003) and effector CD4+ T cells(p=0.01) in mixed tumour neighbourhoods, and CD8+ T cells(p=0.03) in HLADR+ tumour neighbourhoods are positively associated with clinical response to ICI therapy. Evaluation of the inferred regulatory functions between immune cells relative to their tumour proximity by a SpatialScore metric suggests that macrophages may exhibit an immunosuppressive phenotype against both CD4+ and CD8+ T cells, and that this association scores more highly in ICI refractory patients. These spatial patterns are associated with overall survival in addition to ICI response and may indicate features relevant for the functional understanding of the tumour microenvironment.