bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mo and Ni Coordinated Bimetallic Oxide as Catalyst in Modified Separators for Low‐Capacity Decay Lithium Sulfur Batteries
Authors: Wu Tingyi , Dou Huanglin , Zhao Zhenxin , Zhou Junliang , Wang Xiaomin 
Published: April 2023

AbstractLithium‐sulfur (Li−S) batteries are considered to be the most promising candidates for achieving low‐cost, high‐energy density systems. The serious shuttle effect of polysulfides (LiPS) and the sluggish redox kinetics have become major obstacles to the practical application of Li−S batteries. Herein, a hollow microsphere structure of transition bimetallic oxide nickel molybdate (NiMoO4) was prepared by hydrothermal reaction and calcination method. It was used as a separator coating material to inhibit LiPS shuttle and promote efficient redox conversion of sulfur species. The hollow microsphere structure not only possesses a large internal space to physically confine LiPS but also exposes abundant active sites to enhance the redox kinetics of LiPS. The NiMoO4 shows superior adsorption ability for LiPS and accelerated ion/electron transport rates compared to NiO, thus facilitating the anchoring‐conversion‐diffusion processes of polysulfides. Benefiting from this versatility, the Li−S batteries with NiMoO4‐PP exhibit a high discharge specific capacity of 1354.5 mAh g−1 at 0.1 C. In addition, the battery exhibits excellent cycling stability with a capacity decay rate of 0.027% for 500 cycles at 2 C. These results demonstrate the potential application of NiMoO4‐based electrocatalysts in high‐performance Li−S batteries.
Common features of cartilage maturation are not conserved in an amphibian model
Authors: Nguyen Jason K. B. , Gómez‐Picos Patsy , Liu Yiwen , Ovens Katie , Eames B. Frank 
Published: April 2023

AbstractBackgroundMouse, chick, and zebrafish undergo a highly conserved program of cartilage maturation during endochondral ossification (bone formation via a cartilage template). Standard histological and molecular features of cartilage maturation are chondrocyte hypertrophy, downregulation of the chondrogenic markers Sox9 and Col2a1, and upregulation of Col10a1. We tested whether cartilage maturation is conserved in an amphibian, the western clawed frog Xenopus tropicalis, using in situ hybridization for standard markers and a novel laser‐capture microdissection RNAseq data set. We also functionally tested whether thyroid hormone drives cartilage maturation in X tropicalis, as it does in other vertebrates.ResultsThe developing frog humerus mostly followed the standard progression of cartilage maturation. Chondrocytes gradually became hypertrophic as col2a1 and sox9 were eventually down‐regulated, but col10a1 was not up‐regulated. However, the expression levels of several genes associated with the early formation of cartilage, such as acan, sox5, and col9a2, remained highly expressed even as humeral chondrocytes matured. Greater deviances were observed in head cartilages, including the ceratohyal, which underwent hypertrophy within hours of becoming cartilaginous, maintained relatively high levels of col2a1 and sox9, and lacked col10a1 expression. Interestingly, treating frog larvae with thyroid hormone antagonists did not specifically reduce head cartilage hypertrophy, resulting rather in a global developmental delay.ConclusionThese data reveal that basic cartilage maturation features in the head, and to a lesser extent in the limb, are not conserved in X tropicalis. Future work revealing how frogs deviate from the standard cartilage maturation program might shed light on both evolutionary and health studies.
Zebrafishsmarcc1amutants reveal requirements for BAF chromatin remodeling complexes in distinguishing the atrioventricular canal from the cardiac chambers
Authors: Auman Heidi J. , Fernandes Ivy H. , Berríos‐Otero César A. , Colombo Sophie , Yelon Deborah 
Published: April 2023

AbstractBackgroundEssential patterning processes transform the heart tube into a compartmentalized organ with distinct chambers separated by an atrioventricular canal (AVC). This transition involves the refinement of expression of genes that are first found broadly throughout the heart tube and then become restricted to the AVC. Despite the importance of cardiac patterning, we do not fully understand the mechanisms that limit gene expression to the AVC.ResultsWe show that the zebrafish genesmarcc1a, encoding a BAF chromatin remodeling complex subunit homologous to mammalian BAF155, is critical for cardiac patterning. Insmarcc1amutants, myocardial differentiation and heart tube assembly appear to proceed normally. Subsequently, thesmarcc1amutant heart fails to exhibit refinement of gene expression patterns to the AVC, and the persistence of broad gene expression is accompanied by failure of chamber expansion. In addition to their cardiac defects,smarcc1amutants lack pectoral fins, indicating similarity totbx5amutants. However, comparison ofsmarcc1aandtbx5amutants suggests that perturbation oftbx5afunction is not sufficient to cause thesmarcc1amutant phenotype.ConclusionsOur data indicate an important role for Smarcc1a‐containing chromatin remodeling complexes in regulating the changes in gene expression and morphology that distinguish the AVC from the cardiac chambers.
Integrating aspects of affect, reward, and cognition to develop more comprehensive models of binge‐eating pathology
Authors: Schaefer Lauren M. , Forester Glen , Dvorak Robert D. , Steinglass Joanna , Wonderlich Stephen A. 
Published: April 2023

AbstractReward‐related processes are an increasing focus of eating disorders research. Although evidence suggests that numerous distinct reward processes may contribute to eating pathology (e.g., reward learning and delay discounting), existing etiological models of reward dysfunction tend to focus on only a limited number of reward processes, and frequently lack specificity when identifying the individual reward processes hypothesized to contribute to dysregulated eating behavior. Moreover, existing theories have been limited in their integration of reward‐related processes with other demonstrated risk and maintenance factors for eating disorders (e.g., affect and cognition), potentially contributing to underdeveloped models of eating pathology. In this article, we highlight five distinct reward processes with theorized or demonstrated relevance to eating disorders involving binge‐eating, followed by a review of two well‐established risk/maintenance factors for binge‐eating pathology. We then introduce two novel models of binge eating onset and maintenance that integrate these factors (i.e., the Affect, Reward, Cognition models), and discuss methods for testing each of the models in future research. Ultimately, we hope that the proposed models provide a springboard for the continued evolution of more precise and comprehensive theories of reward dysfunction in the eating disorders, as well as the development of novel intervention approaches.Public Significance StatementEating disorders are associated with abnormalities in multiple domains of reward functioning. However, models of reward dysfunction within the eating disorders have not been well‐integrated with prominent models of affect and cognition. This article presents two novel models of onset and maintenance for binge‐eating pathology, which attempt to integrate observed reward abnormalities with other affective and cognitive processes implicated in binge‐type eating disorders.
Optimal prey for red fox cubs—An example of dual optimizing foraging strategy in foxes from a dynamic wetland habitat
Authors: Lanszki József , Bende Zsolt , Nagyapáti Nikolett , Lanszki Zsófia , Pongrácz Péter 
Published: April 2023

AbstractThe red fox (Vulpes vulpes) is the most abundant mesopredator in the Central European region. Detailed knowledge about their feeding behavior is important both from ecological and wildlife management reasons. Food choices of foxes are poorly predictable in high‐biodiversity marshlands. The main aim of our study was to sample parallel the main food‐type abundances in the study area and analyze the diet of fox cubs and cohabiting adults across 3 years during the period of maternal dependence of the cubs. According to the optimal foraging theory, we predicted that the cubs' diet would show higher energy content, would be more varied, and the individual prey species fed to the young would be larger. We analyzed the composition of adult fox and cub fecal samples collected separately around dens in a marshland of western Hungary, May 2014, 2017 and 2020, when the abundance values of main food sources differed. Rodents and waterfowl dominated the diet, but their relative occurrence in the samples showed yearly variations. We found that vixens follow a dual optimizing foraging strategy regarding their provisioning of the cubs and their own diet. Adult foxes optimized their diet according to the actual yearly abundances of their main food sources. Additionally, they preferred prey items that can be consumed at the site of capture (large carrion and small individual prey items). Cubs on the other hand were provisioned with optimal high‐energy food, even if those in question became less abundant in that year. Vixens mostly fed to their young either larger rodents and waterfowl, or multiple small rodents at a time—these type of prey are both optimal for transportation as a single load. Providing optimal prey at an early age in a changing environment may contribute to the ecological success of the red fox.
Manipulating the Oxidation State of CuxO Catalysts to Optimize the Selectivity of Gaseous Products in Electrochemical CO2 Reduction
Authors: Ni Zhiyuan , Li Xiaojuan , Li Xiang , Ji Fushun , Guo Rui , Liu Chunming 
Published: April 2023

AbstractCopper‐based (Cu‐based) catalysts can efficiently convert carbon dioxide to multicarbon products by electrochemical reduction. In this paper, the electrocatalyst with the coexistence of three valence states of Cu(0)‐Cu(I)‐Cu(II) was successfully prepared by adjusting the experimental conditions. The catalyst was derived from Cu/Cu2O prepared on carbon cloth and exhibited excellent CO2 reduction performance. For carbon‐gaseous products, the Faradaic efficiencies for the Cu‐2 catalyst consisting of Cu(0)‐Cu(I)‐Cu(II) were 35.45±3.40 % at −1.66 V vs. RHE, of which 23.85±1.18 % for C2H4. And the synergistic effect of Cu(0)‐Cu(I)‐Cu(II) significantly improved the selectivity of the catalyst to C2H4. This paper provided an efficient method to rationally tune the valence state of Cu‐based catalysts to improve CO2 reduction performance.
A multidimensional examination of affective and cognitive empathy in anorexia nervosa
Authors: Gaggero G. , Luminet O. , Vermeulen N. , De Timary P. , Nandrino J. L. , Goffinet S. , Dereau J. , Shankland R. , Dassonneville C. , Grynberg D. 
Published: April 2023

AbstractSocio‐emotional features are crucial in the development and maintenance of anorexia nervosa (AN). The present study investigates the patterns of altered and preserved empathic abilities in AN. Empathy is an umbrella term that comprises the ability to recognise another's emotional state, take another's perspective, and fantasise (cognitive empathy), as well as the ability to experience vicarious emotions and signal them (affective empathy). These empathic abilities were measured in 43 AN patients and 33 healthy women through a multi‐method approach comprising self‐report measures, behavioural tasks and bodily correlates. Further, we assessed self‐reported approach‐avoidance attitudes towards suffering others. Results showed that, within the domain of cognitive empathy, AN patients reported impairment in recognising emotional expressions of anger and fantasising. Concerning affective empathy, they manifested lower sharing of others’ positive emotions, higher self‐reported distress, and higher facial expressiveness during a video depicting a suffering person. Finally, AN patients reported lower motivation to approach suffering others. Our results draw a complex picture of preserved and altered empathic abilities in AN and capture which are the deficits mediated by the higher levels of anxiety and depression reported by the AN population and those that seem to persist independently from these co‐morbid conditions.
A revised WENO‐THINC scheme for the general structured mesh and applications in the direct numerical simulation of compressible turbulent flows
Authors: Li Jingqi , Liu Cheng , Li Zheng 
Published: April 2023

AbstractThe Tangent of Hyperbola for INterface Capturing (THINC) scheme allows a jump‐like reconstruction and brings about a significant improvement in resolving the discontinuous part of the numerical solutions. However, it is found that the original THINC scheme loses accuracy when working on the stretched, curvilinear or highly‐skewed grid. In this study, we propose a simple strategy to determine the jump thickness parameter in the THINC function, so as to effectively suppress the unphysical oscillation. A Boundary Variation Diminishing (BVD) guideline is introduced to make options between the Weighted Essentially Non‐Oscillatory (WENO) scheme and the modified THINC scheme, thus both the smooth and discontinuous solutions can be reconstructed properly avoiding distortion of grids. Numerical validations indicate that the improved WENO‐THINC‐BVD approach maintains high resolution and is more robust on various types of non‐uniform meshes. The present method is further extended to validate the low‐dissipation property in resolving higher wave numbers portions by simulating an isotropic turbulence decay problem. Finally, we perform the direct numerical simulation (DNS) of a spatially evolving adiabatic flat plate boundary‐layer flow problem at a supersonic Mach number (). Numerical results show the predicted mean flow variables and the normalized shear stress agree well with the experimental data, significant improvements are found in the resolution of the small‐scale vortices, especially in the transition process.
Prognostic impact of the hemoglobin–albumin–lymphocyte–platelet score in patients with oral cavity cancer undergoing surgery
Authors: Fang Ku‐Hao , Lai Chia‐Hsuan , Hsu Cheng‐Ming , Liao Chun‐Ta , Kang Chung‐Jan , Lee Yi‐Chan , Huang Ethan I. , Chang Geng‐He , Tsai Ming‐Shao , Tsai Yao‐Te 
Published: April 2023

AbstractBackgroundWe aimed to probe the hemoglobin–albumin–lymphocyte–platelet (HALP) score's prognostic value in oral cavity squamous cell carcinoma (OSCC).MethodsMedical data of 350 patients with primary operated OSCC were retrospectively reviewed. We derived the optimal HALP cutoff by executing receiver operating characteristic curve analysis, and patients were then grouped based on this cutoff value. Cox proportional hazards model were used to discover survival outcome‐associated factors.ResultsWe derived the optimal HALP cutoff as 35.4. A low HALP score (<35.4) predicted poorer overall and disease‐free survival (hazard ratio: 2.29 and 1.92, respectively; both p < 0.001) and was significantly associated with OSCC aggressiveness. We established a HALP‐based nomogram that accurately predicted overall survival (concordance index: 0.784).ConclusionThe HALP score may be a useful prognostic biomarker in patients with OSCC undergoing surgery, and the HALP‐based nomogram can be a promising prognostic tool in clinical setting.
Major and minor salivary gland cancers: A multicenter retrospective study
Authors: Hacioglu Muhammet Bekir , Erdogan Bulent , Bardakcı Murat , Algın Efnan , Gulbagcı Burcu , Hacibekiroglu Ilhan , Hamdard Jamshid , Olmez Omer Fatih , Akkus Hadi , Oksuzoglu Berna , Goksu Sema Sezgin , Dae Shute Ailia , Sumbul Ahmet Taner , Ugraklı Muzaffer , Karaagac Mustafa , Sahin Elif , Cabuk Devrim , Ozer Ozden , Yavuzsen Tugba , Arıkan Rukiye , Köstek Osman , Atcı Muhammed Mustafa , Sakin Abdullah , Deligonul Adem , Bayır Duygu , Dincer Murat , Unsal Oktay , Yazıcı Ozan , Zeynelgil Esra , Gulmez Ahmet , Harputluoglu Hakan , Erol Cihan , Sendur Mehmet Ali Nahit , Aytekin Aydin , Akagunduz Baran , Oner Irem , Er Ozlem , Oztosun Bugra , Gumus Mahmut , Selçukbiricik Fatih , Aykan Musa Baris , Karadurmus Nuri , Degerli Ezgi , Demirci Nebi Serkan , Turkmen Esma , Şakalar Teoman , Secmeler Saban , Tanrıverdi Ozgur , Alkan Ali , Kemal Yasemin , Cil Ibrahim , Unal Caglar , Iriagaç Yakup , Alan Ozkan , Balli Sevinc , Urun Yuksel , Ozcan Erkan , Turhal Nazım Serdar , Cicin Irfan 
Published: April 2023

AbstractBackgroundMost of the studies on salivary gland cancers are limited for various reasons such as being single‐center, small number of patients, including only major or minor SGCs, or only including epidemiological data.MethodsA total of 37 medical oncology clinics from different regions of Turkey participated in this retrospective‐multicenter study. The analyzed data included clinical and demographical features, primary treatment, metastasis localizations, and treatments and includes certain pathologic features.ResultsThe study included data from a total of 443 SGCs. 56.7% was in major salivary glands and 43.3% was in minor salivary glands. Distant metastasis in the major SGCs was statistically significantly more common than in the minor SGCs, locoregional recurrence was statistically significantly more common in the minor SGCs than in the major SGCs (p = 0.003).ConclusionsEpidemiological information, metastasis and recurrence patterns, treatment modalities, and survival analysis of the patients over 20 years of follow‐up are presented.
Patients with secondary acute myeloid leukemia undergoing allogeneic stem‐cell transplant have inferior outcomes than de novo acute myeloid leukemia regardless minimal residual disease level by flow cytometry
Authors: Núñez‐Torrón Stock Claudia , Jiménez Chillón Carlos , Martín Moro Fernando , Marquet Palomanes Juan , Velázquez Kennedy Kyra , Piris Villaespesa Miguel , Roldán Santiago Ernesto , Rodríguez Martín Eulalia , Chinea Rodríguez Anabelle , García Gutiérrez Valentín , Moreno Jiménez Gemma , López Jiménez Javier , Herrera Puente Pilar 
Published: April 2023

AbstractSecondary acute myeloid leukemia (s‐AML) patients have a poor prognosis and currently the only curative therapy is allogeneic stem‐cell transplant (HSCT). However, we do not yet know whether transplantation is sufficient to reverse the poor prognosis compared to de novo AML patients. We analyzed survival after HSCT comparing a cohort of 58 patients with s‐AML versus 52 de novo patients who were transplanted between 2012 and 2020. Patients with s‐AML had worse event‐free survival (EFS) (p = 0.001) and overall survival (OS) (p < 0.001) compared to de novo AML due to an increased risk of relapse (p = 0.06) and non‐relapse mortality (p = 0.03). The main difference in survival was observed in patients who achieved complete remission (CR) before HSCT (EFS p = 0.002 OS and <0.001), regardless minimal residual disease (MRD) by |multiparametric flow cytometry cohorts. In patients transplanted with active disease (AD), the prognosis was adverse in both s‐AML and de novo AML groups (EFS p = 0.869 and OS p = 0.930). After excluding patients with AD, we stratified the cohort according to conditioning intensity, noticing that s‐AML who received MAC had comparable outcomes to de novo AML, but the survival differences remained among reduce intensity conditioning group. In conclusion, transplanted s‐AML patients have worse survival among patients in CR before HSCT, regardless of MRD level by flow cytometry compared to de novo AML. MAC patients had similar outcomes irrespective of leukemia ontogeny.
Latent class analysis of the Epidemic‐Pandemic Impacts Inventory on mental health outcomes in Siyan Clinical patients
Authors: Shah Anish , Arstein‐Kerslake Olivia , Darling Michele , Morgan Tiffany , Torea Aubree Vance , Laines Helen , Joshi Bhargav , Pena Karina , Young James 
Published: April 2023

AbstractBackground and AimsThe COVID‐19 pandemic has made an outsized negative impact on mental health worldwide. However, research indicates that this impact was not uniform. This study aimed to determine how mental health patients experienced the COVID‐19 pandemic to characterize mental health disparities and identify underlying factors.MethodsWe used the Epidemic‐Pandemic Impacts Inventory (EPII) and latent class analysis to determine the impacts of epidemics and pandemics across several life domains in 245 survey respondents, all of whom were mental health patients at Siyan Clinical. Respondents were predominately White (84.5%) and female (76.3%), with the majority being diagnosed with anxiety or mood disorders (76.3%).ResultsIn the work life domain, respondents in the higher‐impact class were more likely to be employed and/or working in healthcare. In both the home life and emotional/physical health and infection domain, respondents with mood disorders, substance use disorders, or children under 18 living at home were more likely to be in the higher‐impact class. In the home life and positive change domains, respondents that were married were more likely to be in the higher‐impact class, indicating that this group experiences more impacts from the pandemic, both positive and negative. Finally, some groups stood out as having fewer impacts from the pandemic: respondents that were male, over age 55, White, and/or have anxiety disorders were more likely to experience fewer impacts from the pandemic in the work life and home life domains.ConclusionsThis study provides evidence that certain groups may experience greater or fewer impacts from the pandemic.
Low cycle fretting and fretting corrosion properties of low carbon CoCrMo and additively manufactured CoCrMoW alloys for dental and orthopedic applications
Authors: Mace Annsley , Gilbert Jeremy L. 
Published: April 2023

AbstractAdditive manufacturing (AM) of CoCrMo metallic implants is growing in the orthopedic and dental fields. This is due to the traditional alloy's excellent corrosion resistance and mechanical properties. AM processes like selective laser melting (SLM) require less time, materials, and waste than casting or subtractive manufacturing complex‐geometry structures (bridges, partial dentures, etc.). The objective of this work was to investigate the low cycle tribological and tribocorrosion characteristics of AM CoCrMoW alloys compared to wrought LC CoCrMo (ASTM F‐1537) to assess this AM alloy's performance. Fretting and tribocorrosion testing was performed in air (wear only), PBS (wear + corrosion), and PBS with 10 mM H2O2 (wear + corrosion + inflammation) by a single diamond asperity. No variation between alloys in volume of material removed (p = .12), volume of plastic deformation (p = .13), and scratch depth (p = .84) showed that AM was substantially similar in wear resistance to LC in air and PBS. AM exhibited significantly higher fretting currents (p < .01) at loads up to 100 mN ( = 57 nA and  = 49 nA) than LC CoCrMo ( = 30 nA) and ( = 29 nA). In PBS, wear track depth linearly correlates to fretting current, averaged over 100 cycles. Additionally, fretting currents of both alloys were significantly lower in simulated inflammatory conditions compared to PBS alone. AM alloy has generally similar wear and tribocorrosion resistance to wrought LC CoCrMo and would be ideal for patient specific dentistry or orthopedics where precise, complex geometries are required.