bluuebunny/crossref_metadata_2025_split huggingface dataset:
Is truth inconsistent?
Authors: Greenough Patrick 
Published: September 2023

AbstractA popular and enduring approach to the liar paradox takes the concept of truth to be inconsistent. Very roughly, truth is an inconsistent concept if the central principles of this concept (taken together) entail a contradiction, where one of these central principles is Tarski's T‐schema for truth: a sentence S is true if and only if p, (where S says that p). This article targets a version of Inconsistentism which: retains classical logic and bivalence; takes the truth‐predicate “is true” to pick out a property (and determine a non‐empty extension relative to a given world); and holds that liar sentences exhibit a certain kind of indeterminacy in truth‐value. Call such a view Modest Inconsistentism since it is somewhat more conservative in its outlook than various other forms of Inconsistentism. Such a modest view has its attractions: we retain the thesis that the liar sentence is meaningful; we get to respect the claims that there are truths and that there is a property of truth; we get to keep classical logic and bivalence; and, prima facie, no strengthened liar paradox is in the offing. The main aim in this paper is to show that Modest Inconsistentism, despite its initial attractions, is in deep trouble—because it does, after all, give rise to a strengthened liar paradox. We shall also see that there are related kinds of theory which are also subject to the same worry.
A pole new world: Maneuvering masculinity and sexuality among men who pole dance
Authors: Cuccolo Kelly , Haltom Trenton M. 
Published: September 2023

AbstractResearch on cisgender men's experiences in feminized or women‐dominated sports, physical activities, and leisure time has revealed strategies men use to circumvent or maneuver stigmas to minimize negative perceptions. Pole dancing is an under‐researched activity uniquely positioned to understand dynamics of gender and sexuality. In this research dialogue, we present preliminary results from 13 semi‐structured interviews with U.S. men who pole dance to understand how they navigate masculinity and sexuality in pole dancing. First, we find men very strategically disclose their pole dancing to others in the context of the activity's connections to women, gay men, and sex work. Second, we note how men who “pole” often rely on gender essentialist tropes that reinforce the assumption of natural, biological differences between men and women in attempt to legitimize their participation. Third, men who pole are aware of the potential “creepiness” of their presence in pole dance spaces and use this as an opportunity for reflection. Exploring how men rationalize their participation in pole dance is useful to understand the gender and sexual dynamics of men's presence in women‐dominated spaces and broader contemporary masculinities.
Proceedings of the AABB blood center executive summit
Authors: France Christopher , Marks Peter , Jones Jefferson , Sher Graham , Bult Jan M. , Winters Jeffrey L. , Mills Barbeau J. , Carden Bob , Mendelsohn Stone Leah 
Published: September 2023

AbstractAABB hosted the Blood Center Executive Summit on 20 October 2019 during the AABB Annual Meeting in San Antonio, Texas. The session was sponsored by the Commonwealth Transfusion Foundation, a nonprofit, private foundation whose mission is to inspire and champion research and education that optimizes clinical outcomes in transfusion medicine and ensures a safe and sustainable blood supply for the United States. The Summit focused on the intersection of blood centers and plasma centers. Presenters and attendees explored existing and needed data, regulatory requirements, risks and benefits of different donor models, and future direction of the plasma community and blood centers. The Summit also identified priority issues that warrant further investigation and provide opportunities to drive progress. Introductory remarks provided context for the Summit presentations. Debra BenAvram, FASAE, CAE, Chief Executive Officer, AABB (Bethesda, Maryland), noted that during the past year, she and other AABB staff have had many discussions with blood center executives on key issues and challenges. In these talks, many executives requested that AABB provide programming specifically for this member segment. The Summit is a direct result of those requests, and the AABB supports a fruitful discussion as well as important and actionable next steps. Kevin Belanger, DHS, MS, MT(ASCP)SBB, President and Chief Executive Officer of the Shepeard Community Blood Center (Evans, Georgia), observed that he and his colleagues have seen a decrease in the donor base and, at the same time, an increase in plasma centers. He also noted that the resulting discussions about competition and donor compensation have been muted. The Summit provides a forum for a broad, open discussion that can be the start of something important. As chair of the Summit planning committee, he thanked both panelists and audience members for participating. Bob Carden, Chief Executive Officer of the Commonwealth Transfusion Foundation (Richmond, Virginia), who moderated the Summit, joined BenAvram and Belanger in welcoming participants to the day's presentations. He emphasized the need for data and noted that one outcome of the day would be a list of potential research projects that could be pursued and considered for funding.
Factors influencing resilience among breast cancer survivors: Implications for evidence‐based practice
Authors: Kim Myeongshin , Sok Sohyune 
Published: September 2023

AbstractBackgroundBreast cancer survivors are increasing in South Korea, and resilience has become very important in their life.AimsThis study aimed to examine the relationships among anxiety, depression, family support, problem‐focused coping, emotion‐focused coping, self‐efficacy, and resilience, and the factors influencing the resilience of breast cancer survivors.MethodsA cross‐sectional descriptive design was employed. Participants were 153 breast cancer survivors after completion of treatment who were 5 years or less after diagnosis in South Korea. Measures were the general characteristics list, Korean version of Connor‐Davidson Resilience Scale, Korean version of Hospital Anxiety and Depression Scale, family support scale, Korean version of Ways of Coping Checklist, and Self‐Efficacy Scale.ResultsThe strongest predictor that influenced resilience was depression (β = −0.32), followed by family support (β = 0.23) and problem‐focused coping (β = 0.15). Resilience levels in breast cancer survivors after completion of treatment were relatively low.Linking Evidence to ActionInterventions using problem‐focused coping, including family members, could increase resilience, thus, moving away from focusing solely on the perspectives of cancer survivors when developing and implementing support interventions. Nurses should pay attention to influencing factors to help improve the resilience of breast cancer survivors during the extended survivorship phase.
Homotopy of manifolds stabilized by projective spaces
Authors: Huang Ruizhi , Theriault Stephen 
Published: September 2023

AbstractWe study the homotopy of the connected sum of a manifold with a projective space, viewed as a typical way to stabilize manifolds. In particular, we show a loop homotopy decomposition of a manifold after stabilization by a projective space, and provide concrete examples. To do this, we trace the effect in homotopy theory of surgery on certain product manifolds by showing a loop homotopy decomposition after localization away from the order of the image of the classical ‐homomorphism.
A Comparative Study of the Entanglement Models Toward Simulating Hyperelastic Behaviors
Authors: Zhu Lingrui , Zhan Lin , Xiao Rui 
Published: September 2023

Abstract
Accurately predicting the hyperelastic response of soft materials under complex loading conditions has been a long-standing challenge. Previous developments have shown that incorporating the entanglement effect can significantly improve the model performance. In this work, we compare the performances of different entanglement models in simulating the stress responses through either fitting uniaxial data alone or uniaxial and equi-biaxial data simultaneously. Results show that the entanglement models do not exhibit satisfactory predictive ability with parameters calibrated through uniaxial data. This disadvantage can be overcome through a newly proposed Biot chain model, which inherently incorporates the entanglement effect through a new chain stretch determination that considers the contribution of all surrounding chains. As multiple pairs of experimental data are used to calibrate the model parameter, the Davidson–Goulbourne model provides the best performance. It is also demonstrated that the entanglement effect varies with the deformation mode and plays a more critical role in biaxial deformation than that in the uniaxial deformation. This study can provide a better understanding of entanglement models, including their capabilities and limitations, so as to facilitate the development of more accurate and reliable predictive models for various applications.
The
in vitro
effect of new combinations of carbapenem–β-lactamase inhibitors for
Mycobacterium abscessus
Authors: Fröberg Gabrielle , Ahmed Ayan , Chryssanthou Erja , Davies Forsman Lina 
Published: September 2023

ABSTRACT

As new treatment alternatives for
Mycobacterium abscessus
complex (MABC) are urgently needed, we determined the minimum inhibitory concentrations (MICs) for novel carbapenem combinations, including imipenem-relebactam and tebipenem-avibactam against 98 MABC isolates by broth microdilution. The MIC50 was reduced from 16 to 8 mg/L by adding relebactam to imipenem, while the addition of avibactam to tebipenem showed a more pronounced reduction from 256 to 16 mg/L, representing a promising non-toxic, oral treatment option for further exploration.
Effective gene silencing using type I–E CRISPR system in the multiploid, radiation-resistant bacterium
Deinococcus radiodurans
Authors: Misra Chitra S. , Pandey Neha , Appukuttan Deepti , Rath Devashish 
Published: September 2023

ABSTRACT

The extremely radiation-resistant bacterium,
Deinococcus radiodurans
, is a microbe of importance, both, for studying stress tolerance mechanisms and as a chassis for industrial biotechnology. However, the molecular tools available for use in this organism continue to be limiting, with its multiploid genome presenting an additional challenge. In view of this, the clustered regularly interspaced short palindromic repeat (CRISPR)-Cas tools provide a large repertoire of applications for gene manipulation. We show the utility of the type I-E Cascade system for knocking down gene expression in this organism. A single-vector system was designed for the expression of the Cascade components as well as the crRNA. The type I-E Cascade system was better tolerated than the type II-A dCas9 system in
D. radiodurans
. An assayable acid phosphatase gene,
phoN
integrated into the genome of this organism could be knocked down to 10% of its activity using the Cascade system. Cascade-based knockdown of
ssb
, a gene important for radiation resistance resulted in poor recovery post-irradiation. Targeting the Radiation and Desiccation Response Motif (RDRM), upstream of the
ssb
, prevented de-repression of its expression upon radiation exposure. In addition to this, multi-locus targeting was demonstrated on the deinococcal genome, by knocking down both
phoN
and
ssb
expression simultaneously. The programmable CRISPR interference tool developed in this study will facilitate the study of essential genes, hypothetical genes, and
cis
-elements involved in radiation response as well as enable metabolic engineering in this organism. Further, the tool can be extended for implementing high-throughput approaches in such studies.

IMPORTANCE

Deinococcus radiodurans
is a microbe that exhibits a very high degree of radiation resistance. In addition, it is also identified as an organism of industrial importance. We report the development of a gene-knockdown system in this organism by engineering a type I-E clustered regularly interspaced short palindromic repeat (CRISPR)-Cascade system. We used this system to silence an assayable acid phosphatase gene,
phoN
to 10% of its activity. The study further shows the application of the Cascade system to target an essential gene
ssb
, that caused poor recovery from radiation. We demonstrate the utility of CRISPR-Cascade to study the role of a regulatory
cis
-element in radiation response as well as for multi-gene silencing. This easy-to-implement CRISPR interference system would provide an effective tool for better understanding of complex phenomena such as radiation response in
D. radiodurans
and may also enhance the potential of this microbe for industrial application.
Association between diseases of despair and atherosclerotic cardiovascular disease among insured adults in the USA: a retrospective cohort study from 2017 to 2021
Authors: Nudy Matthew , Galper Kathleen , George Daniel R , Williams Brent A , Kraschnewski Jennifer L , Sinoway Lawrence , Brignone Emily 
Published: September 2023

ObjectivesTo assess associations between diseases of despair (DoD) and incident atherosclerotic cardiovascular disease (ASCVD) among insured adults in the USA.DesignRetrospective cohort study.SettingHighmark insurance claims data in the USA from 2017 to 2021.ParticipantsAdults with at least 10 months of continuous insurance enrolment, no record of ASCVD in the 2016 baseline year and no missing data on study variables.Primary and secondary outcome measuresCox proportional hazard regression was used to calculate crude and adjusted hazard ratios (HR) and 95% confidence intervals (CI) to assess risk of ASCVD (composite of ischaemic cardiomyopathy, non-fatal ischaemic stroke, peripheral arterial disease or non-fatal acute myocardial infarction) by baseline DoD overall, and by the component conditions comprising DoD (alcohol-related disorders, substance-related disorders, suicidality) individually and in combination.ResultsThe DoD-exposed group had an age-adjusted rate of 20.5 ASCVD events per 1000 person-years, compared with 11.7 among the unexposed. In adjusted models, overall DoD was associated with increased risk of incident ASCVD (HR 1.42, 95% CI 1.36 to 1.47). Individually and in combination, component conditions of DoD were associated with higher risk for ASCVD relative to no DoD. Substance-related disorders were associated with 50% higher risk of incident ASCVD (HR 1.5, 95% CI 1.41 to 1.59), alcohol-related disorders and suicidality/intentional self-harm were associated with 33% and 30% higher risk, respectively (HR 1.33, 95% CI 1.26 to 1.41; HR 1.30, 95% CI 1.11 to 1.52). Co-occurring DoD components conferred higher risk still. The highest risk combination was substance-related disorders+suicidality (HR 2.01, 95% CI 1.44 to 2.82).ConclusionsAmong this cohort of insured adults, documented DoD was associated with increased ASCVD risk. Further research to understand and address cardiovascular disease prevention in those with DoD could reduce costs, morbidity and mortality. Further examination of overlapping structural factors that may be contributing to concurrent rises in ASCVD and DoD in the USA is needed.
Study protocol for IMPRoVE: a multicentre prospective observational cohort study of the incidence, impact and mechanisms of perioperative right ventricular dysfunction in non-cardiac surgery
Authors: Keast Thomas , McErlane James , Kearns Rachel , McKinlay Sonya , Raju Indran , Watson Malcolm , Robertson Keith E , Berry Colin , Greenlaw Nicola , Ackland Gareth , McCall Philip , Shelley Benjamin 
Published: September 2023

IntroductionPerioperative myocardial injury evidenced by elevated cardiac biomarkers (both natriuretic peptides and troponin) is common after major non-cardiac surgery. However, it is unclear if the rise in cardiac biomarkers represents global or more localised cardiac injury. We have previously shown isolated right ventricular (RV) dysfunction in patients following lung resection surgery, with no change in left ventricular (LV) function. Given that perioperative RV dysfunction (RVD) can manifest insidiously, we hypothesise there may be a substantial burden of covert yet clinically important perioperative RVD in other major non-cardiac surgical groups. The Incidence, impact and Mechanisms of Perioperative Right VEntricular dysfunction (IMPRoVE) study has been designed to address this knowledge gap.Methods and analysisA multicentre prospective observational cohort study across four centres in the West of Scotland and London. One hundred and seventy-five patients will be recruited from five surgical specialties: thoracic, upper gastrointestinal, vascular, colorectal and orthopaedic surgery (35 patients from each group). All patients will undergo preoperative and postoperative (day 2–4) echocardiography, with contemporaneous cardiac biomarker testing. Ten patients from each surgical specialty (50 patients in total) will undergo T1-cardiovascular magnetic resonance (CMR) imaging preoperatively and postoperatively. The coprimary outcomes are the incidence of perioperative RVD (diagnosed by RV speckle tracking echocardiography) and the effect that RVD has on days alive and at home at 30 days postoperatively. Secondary outcomes include LV dysfunction and clinical outcomes informed by Standardised Endpoints in Perioperative Medicine consensus definitions. T1 CMR will be used to investigate for imaging correlates of myocardial inflammation as a possible mechanism driving perioperative RVD.Ethics and disseminationApproval was gained from Oxford C Research Ethics Committee (REC reference 22/SC/0442). Findings will be disseminated by various methods including social media, international presentations and publication in peer-reviewed journals.Trial registration numberNCT05827315.
Iatrogenic air embolism: influence of air bubble size on cerebral infarctions in an experimental in vivo and numerical simulation model
Authors: Schaefer Tabea C , Greive Svenja , Bierwisch Claas , Mohseni-Mofidi Shoya , Heiland Sabine , Kramer Martin , Möhlenbruch Markus A , Bendszus Martin , Vollherbst Dominik F 
Published: September 2023

BackgroundCerebral infarctions resulting from iatrogenic air embolism (AE), mainly caused by small air bubbles, are a well-known and often overlooked event in endovascular interventions. Despite their significance, the underlying pathophysiology remains largely unclear.MethodsIn 24 rats, AEs were induced using a microcatheter, positioned in the carotid artery via femoral access. Rats were divided into two study groups, based on the size of the bubbles (85 and 120 µm) and two sub-groups, differing in air volume (0.39 and 0.64 µl). Ultra-high-field magnetic resonance imaging (MRI) was performed 1.5 hours after intervention. MRI findings including the number, single volume and total volume of the infarctions were assessed. A software-based numerical simulation was performed to qualitatively assess the microvascular pathomechanisms.ResultsIn the study groups 22 of 24 rats (92%) revealed cerebral infarctions. The number of infarctions per rat was higher for the smaller bubbles, for the lower (medians: 5 vs 3; p=0.049) and higher air volume sub-groups (medians: 6 vs 4; p=0.012). Correspondingly, total infarction volume was higher for the smaller bubbles (1.67 vs 0.5 mm³; p=0.042). Simulations confirmed the results of the experiments and suggested that fusion of microbubbles to larger bubbles is the underlying pathomechanism of vascular occlusions.ConclusionIn iatrogenic AE, the size of the bubbles can have a major impact on the number and total volume of cerebral infarctions. These findings can help to better understand the pathophysiology of this frequent, often underestimated adverse event in endovascular interventions.
Characterizing Some Types of Uninorms on Bounded Lattices
Authors: Wen Huayan , Wu Xinxing , Çaylı Gül Deniz 
Published: September 2023

Uninorms, as important generalizations of triangular norms and conorms, let the identity [Formula: see text] exist anywhere on a bounded lattice. In this paper, we focus on new characterizations of uninorms allowed to act on more general bounded lattices. In particular, we present several necessary and sufficient conditions to verify the construction approaches introduced by (Çaylı and Karaçal, Kybernetika 53 (2017) 394–417) and (Çaylı, Fuzzy Sets Syst. 395 (2020) 107–129), yielding a uninorm on bounded lattices.
Home-Based Enrichment Activities for Science 9 (Biology): Effects on Students’ Academic Performance and Science Engagement
Authors: Antipatia Jade Mark L. 
Published: September 2023

This study aimed to develop Home-Based Enrichment Activities specifically designed for Science 9 and assess their impact on academic performance and engagement of Grade 9 students attending public high schools in the Philippines during the first quarter of the school year 2022-2023. This study employed both descriptive and quasi-experimental research methods. The instruments included the validated pre-test and post-test assessments, a survey questionnaire for teachers, and a survey sheet for students. The data was collected from (60) students, (15) high school teachers and (15) master teachers in science in public schools. The data gathered were statistically analyzed using weighted mean, percentage, independent-samples t-Test, paired t-Test, and z-Test. Results showed that the control group exhibited lower mean scores (4.33 and 29.33) in the pretest and posttest compared to the experimental group (13.97 and 38.20), indicating a significant improvement in performance of the students, further affirming the positive impact of the developed Home-based enrichment activities on academic performance. The experimental group also expressed a high level of science learning engagement, demonstrating strong involvement, effort, and preparation in science lessons as manifested by the grand weighted mean of 3.88. Recommendations include incorporate home-based enrichment activities into blended learning modalities, particularly in modular distance learning to help students to learn the lesson and answer their modules on their own and increase students’ achievement in Science. Additionally, these supplementary activities can also provide valuable support to students who are at risk of failing a specific subject due to time constraints and challenging learning tasks within their modules.