bluuebunny/crossref_metadata_2025_split huggingface dataset:
Molecular Surveillance for Vector-Borne Bacteria in Rodents and Tree Shrews of Peninsular Malaysia Oil Palm Plantations
Authors: Mohd-Azami Siti Nurul Izzah , Loong Shih Keng , Khoo Jing Jing , Husin Nurul Aini , Lim Fang Shiang , Mahfodz Nur Hidayana , Ishak Siti Nabilah , Mohd-Taib Farah Shafawati , Makepeace Benjamin L. , AbuBakar Sazaly 
Published: January 2023

Many human clinical cases attributed to vector-borne pathogens are underreported in Malaysia, especially in rural localities where healthcare infrastructures are lacking. Here, 217 small mammals, consisting of rodents and tree shrews, were trapped in oil palm plantations in the Peninsular Malaysia states of Johor and Perak. Species identification was performed using morphological and DNA barcoding analyses, and 203 small mammals were included in the detection of selected vector-borne bacteria. The DNA extracted from the spleens was examined for Orientia tsutsugamushi, Borrelia spp., Bartonella spp. and Rickettsia spp. using established PCR assays. The small mammals collected in this study included Rattus tanezumi R3 mitotype (n = 113), Rattus argentiventer (n = 24), Rattus tiomanicus (n = 22), Rattus exulans (n = 17), Rattus tanezumi sensu stricto (n = 1) and Tupaia glis (n = 40). Orientia tsutsugamushi, Borrelia spp. and Bartonella phoceensis were detected in the small mammals with the respective detection rates of 12.3%, 5.9% and 4.9%. Rickettsia spp., however, was not detected. This study encountered the presence of both Lyme disease and relapsing fever-related borreliae in small mammals collected from the oil palm plantation study sites. All three microorganisms (Orientia tsutsugamushi, Borrelia spp. and Bartonella phoceensis) were detected in the R. tanezumi R3 mitotype, suggesting that the species is a competent host for multiple microorganisms. Further investigations are warranted to elucidate the relationships between the ectoparasites, the small mammals and the respective pathogens.
"Saídas do armário diferentes em tempos diferentes”: a heteronormatividade e suas implicações subjetivas em universitários cis-gays
Authors: Meireles Victor Hugo Brandão , Ferrarini Norma da Luz 
Published: January 2023

A pesquisa fundamenta-se na Epistemologia Qualitativa, Teoria da Subjetividade e Metodologia Construtivo-interpretativa propostas por Fernando González Rey, com base na Psicologia Cultural-Histórica e no materialismo histórico e dialético. Objetiva investigar as implicações da heteronormatividade na produção de sentidos subjetivos e configurações subjetivas de três estudantes gays cisgêneros de uma universidade pública que participaram do espaço conversacional sobre “Sair do armário: estigmas e vivências”. Foram geradas duas hipóteses: ‘O armário não está em nenhum lugar: O não lugar do homossexual’ (H1) e ‘Silenciamento da sexualidade’ (H2). A pesquisa demonstrou que a Teoria da Subjetividade produz zonas de inteligibilidade sobre as temáticas heteronormatividade, sair do armário e identidade gay. A partir da interpretação e construção da informação sobre o processo sair do armário, construímos a definição de identidade gay como uma síntese de configurações subjetivas sobre sexualidade complexa e contraditória composta de sentidos subjetivos simbólico-emocionais diversos produzidos em diferentes experiências e vivências relacionadas ao que se denomina “assumir-se gay”, de forma articulada com a realidade histórico-cultural concreta. A partir dessas experiências e vivências sobre o processo “sair do armário” podemos dizer que se trata de um projeto político de identidade enquanto um processo emancipatório e torna possível esses sujeitos desenvolverem autonomia para legitimarem suas identidades e expressá-las em qualquer espaço social.
Tuberculosis screening and early diagnostics in adolescents in Primorsky Krai
Authors: Motanova L. N. , Kalashnikov P. E. 
Published: January 2023

Aim. To define the objectives of phthisiatric service with respect to organizing screening for tuberculosis infection (TB) and early diagnostics among adolescents in Primorsky Krai.Material and Methods. The data of epidemiological monitoring conducted by the Primorsky Regional TB Dispensary in 1994–2021 were analyzed. The TB incidence, clinical structure of newly-diagnosed cases, phases of the tuberculosis process, as well as the presence of bacterial excretion were assessed. At a level of 0.95, the statistical hypothesis of equal shares was tested under an alternative hypothesis.Results. The implementation of mass immunodiagnostics using the recombinant tuberculosis allergen (TBA) by medical organizations, which are joint into a unified medical network, improves screening efficiency of TB among adolescents. This is confirmed by a decreased TB incidence rate and improved clinical structure of newly-diagnosed cases. The prevalence of secondary TB forms in the clinical structure of newly-diagnosed cases in adolescents justifies the importance of annual fluorographic examination. Annual RTA testing and fluorographic examination of the chest in adolescents once every six months should be a priority anti-tuberculosis measure.Conclusions. TB in adolescents remains to be a serious phthisiological problem. An effective system of screening and early detection of TB in adolescents should include mass immunodiagnostics and, with an interval of six months, fluorographic examination of the chest.
Epidemic situation of tuberculosis in the Far Eastern Federal District of Russia in 2021
Authors: Sterlikov S. A. , Aksyonova V. A. , Mikhailova Yu. V. , Kucheryavaya D. A. 
Published: January 2023

Aim. To analyze the epidemic situation of tuberculosis (TB) in the Far Eastern Federal District of Russia in the context of implementation of a targeted governmental program “Prevention and control of socially significant infectious diseases.”Materials and methods. Performance indicators were calculated based on the information derived from official statistical forms. Conventional calculation methods were used.Results. The incidence of TB in the Far Eastern Federal District amounted to 51.0 per 100 thousand population under the target value of 41.0. The coverage of population with preventive TB screening comprised 72.9% under the target value of 72.5% (achieved). The mortality rate in tuberculosis patients was 9.1 per 100 thousand population under the target value of 6.0. The maximum mortality rates were recorded in the Amur Oblast (15.8) and Primorsky Krai (15.3) with 55.6% of fatal cases. The share of newly-diagnosed TB cases in prisons comprised 7.7% under the target value of 7.6%. The share of newly-diagnosed pulmonary TB cases with a culture-positive result was 56.5%, which exceeded the target value of 55.5%. However, this indicator was extremely low in the Chukotka Autonomous Okrug (26.9%), Zabaykalsky Krai (29.7%), and Jewish Autonomous Oblast (31.9%). The indicator “Effectiveness of the treatment of patients with multidrug-resistant tuberculosis” was 55.9% under the target value of 57.5%. The main problem of achieving this indicator was associated with insufficient adherence of patients to treatment.Conclusions. Tuberculosis remains to be a serious problem in the Far Eastern Federal District of Russia. Only two out of six indicators of the targeted governmental program were achieved. The epidemic situation in the Primorsky Krai and Amur Oblast requires increased attention due to their significant role in the Far Eastern Federal District as a whole. Efforts should be aimed at improving laboratory diagnostics of TB and developing programs of psychosocial support for TB patients.
Modern immunological tests for early detection of tuberculosis infection in children in the Yaroslavl Oblast
Authors: Astafiev A. S. , Takhkhan A. , Vasilyeva L. A. , Vinogradova A. S. 
Published: January 2023

Objective. To evaluate the efficacy of immunological tests for early detection of tuberculosis infection in children in the Yaroslavl Oblast (Russia).Material and methods. Medical records of 354 children and adolescents examined by ELISPOT (Enzyme-Linked ImmunoSpot) assay (T-SPOT.TB) in the Yaroslavl Oblast in 2020–2022 were studied. Four groups of children were distinguished: group 1 included children with active tuberculosis (n = 3); group 2 included children under 7 with altered tuberculin sensitivity (conversion of the tuberculin test) or children over 8 first-time tested positive for RTA, who were under the supervision of a phthisiatrician in the VI A group of dispensary registration (n = 52); group 3 included children with medical exemptions from screening immunodiagnostics (n = 49); and group 4 included children with refusals of their parents or legal representatives from skin tests (n = 250).Results. The sensitivity of both RTA and T-SPOT.TB tests achieved 100%, with the concordance level of 100%. When assessing discordant results (positive result for RTA and negative for T-SPOT.TB) in the VI A dispensary registration group, the majority of children were found to have an aggravated allergic anamnesis and somatic pathology. The maximum number of children examined by the laboratory method included those whose parents or legal representatives refused from skin test administration (70.6%).Conclusions. T-SPOT.TB is an optimal method for early detection of latent TB infection and TB in children at risk, including those with medical contraindications for skin tests or whose parents refused from screening immunodiagnostics.
TREC as a personalized tuberculosis predictor in infants and preschool children
Authors: Smerdin S. V. , Plekhanova M. A. , Kalinina O. A. , Ludanny R. I. , Lazebny S. V. , Filippov P. N. , Kazakov A. V. , Kudlay D. A. , Pahlavonova A. D. 
Published: January 2023

Aim. Quantitative assessment of TREC and KREC in infants and preschool children infected with tuberculosis infection (TI). Material and methods. A prospective cross-sectional study was conducted in 2022. The observation group consisted of 87 children of early childhood age in contact with TB patients, of whom 27 were diagnosed with TB, 34 were tested positive to TB based on skin tests without signs of a local specific process (TI), 26 were children without signs of tuberculosis infection according to the results of skin tests and local process (conditionally healthy children).Results. The following factors significant in the assessment of tuberculosis infection were determined: anti-tuberculosis therapy (F = 42.001; p = 0.000001); positive or negative response to the tuberculosis recombinant allergen (RTA) during an intradermal test (F = 39.394; p = 0.000001); high TREC levels in the blood (F = 12.707; p = 0.000001); the presence of a tuberculin response (F = 10.625; p = 0.000006); and KREC levels (F = 3.182; p = 0.039). Conclusions. According to the obtained results, TREC levels can be considered as a personalized risk predictor of tuberculosis infection in infants and preschool children.
A screening study of latent tuberculosis infection in children in a metropolis city
Authors: Sevostyanova T. A. , Shamuratova L. F. , Zubova O. V. , Slogotskaya L. V. , Korchagin M. P. 
Published: January 2023

Objective. To carry out a screening study among children and adolescents for tuberculosis infection in the city of Moscow using modern immunodiagnostic methods.Materials and methods. The results of a mass screening study for tuberculosis prevalence in the pediatric population of a metropolis city were analyzed. The study was conducted during 2019–2021 in Moscow using the Mantoux skin test with 2 TE PPD-L and a skin test with a recombinant tuberculosis allergen (RTA), as well as the indicators of tuberculosis incidence in children.Results. The introduction of mass screening for tuberculosis based on RTA among the pediatric population and subsequent work with the identified risk groups contributed to a decrease in the number of newly-diagnosed cases. In 2019–2021, the incidence of tuberculosis among children in Moscow did not exceed 3.8 per 100 thousand children aged 0–17 years, with this number varying from 1.2 to 2.1 among permanent residents. The risk indicators of primary infection among children aged 1–7 according to the Mantoux test (0.37% in 2019, 0.47%, in 2020, and 0.35% in 2021) and the prevalence of latent tuberculosis according to the results of screening based on RTA among children aged 8–17 in 2019–2021 (no more than 0.3%) indicate a stable epidemiological situation as regards tuberculosis infection in the city.Conclusions. The development of an effective monitoring system for preventive tuberculosis screening among urban pediatric populations contributed to the detection of latent tuberculosis cases prior to the development of its local forms. The subsequent implementation of preventive measures in risk groups allowed the incidence of tuberculosis among children to be reduced.
24-hour blood pressure monitoring in patients with polycythemia vera
Authors: Gorskij P. O. , Goncharova E. V. 
Published: January 2023

Aim. To study the parameters of 24-hour blood pressure monitoring in patients with polycythemia vera and to determine their informational value for the diagnosis of heart damage.Materials and methods. Blood pressure parameters were monitored daily in 63 patients with I–IIB stage polycythemia vera and 52 healthy individuals to determine the occurrence of their pathological types. The sensitivity and specificity of the studied parameters were evaluated using ROC analysis for early diagnosis of heart damage in polycythemia patients. The obtained information was processed in Statistica 25.0.Results. An analysis of blood pressure load showed that 47.6%, 30.1% and 34.9% of polycythemia patients suffer from systolic arterial hypertension (p = 0.012), daytime diastolic arterial hypertension (p = 0.03), and nocturnal diastolic arterial hypertension (p = 0.001), respectively. In comparison with healthy individuals, polycythemia patients experienced a higher variability of systolic (p<0.002) and diastolic (p<0.001) blood pressure, as well as the morning surge of systolic pressure (p = 0.014), more frequently. In 69.8% of polycythemia patients, pathological types of 24-hour blood pressure profile – with either insufficient or excessive nocturnal reduction – were observed. Informative parameters of heart damage in polycythemia patients were found to include blood pressure load, minimum daytime systolic and diastolic blood pressure, and the rate of nocturnal decrease in diastolic pressure.Conclusions. (1) Systolic-diastolic arterial hypertension was detected in half of polycythemia patients, with pathological types of 24-hour blood pressure profile observed in the majority of patients. (2) The parameters of 24-hour blood pressure monitoring can be used for early diagnosis of heart damage in patients with polycythemia vera.
The Relationship between Psychological Prosperity and Irrational Ideas in Light of the Midlife Crisis of Both Sexes in the Kingdom of Saudi Arabia
Authors: Mahboob Hanan 
Published: January 2023

The study aims to identify the relationship between psychological prosperity and irrational ideas in light of the midlife crisis for both sexes in the Kingdom of Saudi Arabia, and the differences in psychological prosperity and irrational ideas according to the two variables of gender (male / female), and social status (married/unmarried).
The descriptive method was applied, the study was applied to a sample of (805) males and females, (365) males, and (440) females, middle age (47.2) years., and (440) women, with an average age of (47.2) years, The study tools were the Psychological Prosperity Scale and the Irrational Ideas Scale were applied, prepared by the researcher, and Results of the study revealed that there is a statistically significant correlation between the degrees of psychological prosperity and the degrees of irrational ideas among the members’ sample of the research , Where the correlation coefficient was 0.883, which is significant at the level of significance (0.01). There was no statistically significant difference between the mean scores of the members’ sample in psychological prosperity according to the variables of gender and social status at the significance level (0.05), and there are no statistically significant differences between the mean scores of the sample members in irrational ideas according to the gender at the significance level (0.05)
There are significant differences Statistically among the average scores of the members’ sample in the degrees of irrational Ideas according to social status (0.01), in favor of the unmarried, they are more susceptible to irrational ideas.
Consumerism and its Relation to Self -Identity: A Field Study on the Students of the University of Jordan
Authors: Abu Zaghlan Majd , Al-Wraikat Ayed 
Published: January 2023

The study aims at identifying the relation between consumerism and the self identity. For this purpose, a questionnaire was designed as the study tool and consisted of two parts; the first part comprised of the demographic data whereas the second one comprised of a measurement scales of the consumerism (four-dimension scale) and self identity (one-dimension scale). On a theoretical level, this study considered some of the assumptions of Zygmunt Bauman’s work, especially “Liquid Modernity” theory. The social survey method was used and applied to an organized random sample from the students of the University of Jordan. Descriptive statistics, analysis of variance, correlation, T-test and the multi-regression test were used. The study concluded that the sample subjects scored an average level for each of the cultural dimension, subjective dimension, and symbolic dimension of consumerism. However, the social dimension scored a low level. The study revealed that the sample subjects had high level of self identity. The independent variable (consumerism) interprets (0.026) of the variables occurring in the dependent variable (self identity). There was negative correlation between the consumerism in its subjective dimension and the self identity that resulted in reduced identification of the self identity. It was revealed that the symbolic dimension of consumerism is the second reason for the changes affecting the self identity; in fact, there was a positive correlation between them. However, the other dimensions of consumerism were not statistically significant.
Design of Embedded IoT based Medicine Feeder Box
Authors: Chinchanikar Akshay , CHANDANKHEDE PANKAJ , Titarmare Abhijit 
Published: January 2023

<p> This paper introduced the development of the ESP Module-based pill reminder, which will enable patients to obtain a prescription at the right time and time. Assisted automation is another technology that can bring great benefits to humans. Today, however, only 2 out of 50 people use assistive automation due to its high cost, lack of information on the subject, and availability. By 2050, one in 20 households will need a support product and most adults will need 2 or more of her products. I also found that people pay more attention to their work than their health. This procedure aims to alleviate the problem by reminding you to take your medication anywhere within the designated time and to contact the appropriate contacts. It is a combination of a patient's physical and digital memory, which is important for communities of all ages, but especially effective for physicians with disabilities who forget to take their medications. The main goal is to keep the system useful and cost effective. The presented system uses ESP Module, AC motor, PIR sensor, Buzzer with alarm used to bring victims closer to receive the required doses according to the doctor's note at the right hour. This practical and economic program will treat older patients, especially illiterate patients. This smart pill box can alleviate the burden on elderly family members by reminding them to take their medication on time, especially with infections like Covid-19 </p>
Surgical dental rehabilitation of patients in remission of oncological diseases: assessment of treatment outcomes and quality of life
Authors: Bazikyan E. A. , Arishkova V. V. , Anisimov D. V. 
Published: January 2023

Satisfaction with the results of complex dental treatment, and its impact on the quality of life of patients in the conditions of previously conducted complex or combined anticancer therapy.Aim. To assess the change in the quality of life of patients in remission of oncological diseases after complex dental treatment.Materials and methods. Quality of life and aesthetic outcome were assessed using the University of Washington scale (UWQOL) and visual analog scale. The data were analyzed and a comparative evaluation of the results of the main and control groups was carried out.Result. In both groups, different results of satisfaction with appearance and functionality were obtained, patients of the main group demonstrated high rates of chewing function, psychological comfort and comfort when eating in public (p < 0.01).Conclusions. This study proves that surgical dental rehabilitation of patients in remission of oncological diseases with partial or complete absence of teeth allows patients to significantly improve their quality of life.
Development of a gum recession model in an experiment
Authors: Lopatina N. V. , Hajbullina R. R. , Danilko K. V. , Shangina O. R. , Tuhvatullina D. N. , Kurbanova K. A. 
Published: January 2023

Background: The article presents experimental studies conducted on Wistar rats in the amount of 50 individuals. An artificial gum recession defect was created.Aim: to evaluate the effectiveness of creating a gum recession model in the proposed way.Material and methods: Experimental animals at the beginning of the study had an intact oral mucosa: pale pink color, without pathological changes. An experimental model of gum recession was created by excision of V-shaped periodontal tissues from the vestibular surface in the area of the lower jaw incisors of a rat, then a DispodentPak No. 000 retraction thread was applied in the area of the lower central incisors in the circular ligament of the tooth to a depth of 1.5 mm, and Vitrebond dental glass ionomer cement was applied to the vestibular surface of the neck of the tooth of the lower incisors, with at the same time, prednisone is administered intramuscularly at the rate of 12 mg / kg of animal weight on the 1st, 3rd and 5th day. For the experiment, female white rats in the amount of 50 individuals were used as a model. All animals were divided into 2 groups depending on the method of creating a gum recession defect. In the control group of rats, the defect was created according to the standard procedure by conducting a V-shaped incision.Results: When creating the proposed model of experimental gum recession, the clinical and pathomorphological picture is achieved under the influence of local factors: V-shaped gum incision, retraction thread, dental glass ionomer cement. To suppress the processes of self-regeneration of the gums, the optimal dose of prednisone is administered.Conclusions: On the 3rd day of the experiment, a V-shaped defect was observed in animals. On the 10th day, clinical signs of gum recession are determined: a defect with a depth of 2 mm. The average depth of recession in animals was (2 ± 1.7 mm). A relatively short process of modeling a gum recession (no more than a month). In this case, a local lesion of the gum is created, not burdened by any other pathology in the animal, and having both local and general (stress) pathogenetic factors, against the background of changes in the reactivity of the organism, which corresponds to the modern theory of the occurrence of recession as a polyethological disease in humans.