bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of anxiety and depressive symptoms with C-reactive protein in diverse Latinos: Results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)
Authors: Guerrero Lourdes R. , Hong Suzi , Tarraf Wassim , Perreira Krista , Camacho Álvaro , Kohn Jordan N. , Jimenez Daniel E. , Talavera Gregory A. , Gallo Linda , Allison Matthew A. , Wassertheil-Smoller Sylvia , González Hector M. 
Published: August 2023

Background
High sensitivity C-reactive protein (hsCRP) is a marker of systemic inflammation that has been associated with persistent depressive symptoms. Depression and anxiety are frequently associated with a chronic inflammatory state, yet the nature of this relationship has not been rigorously examined in diverse Hispanic/Latino populations. We aimed to study the association of anxiety and depressive symptoms as well as comorbid presentations, with circulating high sensitivity C-reactive protein (hsCRP) levels in a large Latino cohort of diverse heritages. We hypothesized a significant positive associations of both anxiety and depressive symptoms and hsCRP levels and potential variations among the heritage groups.

Methods
Depressive symptoms and anxiety were measured by the Center for Epidemiological Studies Depression Scale (CES-D) and State-Trait Anxiety Inventory (STAI), respectively. Serum hsCRP (hsCRP) levels of 15,448 participants (age 18 to 75 years; 52.3% women) from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) were measured and categorized based on the established cardiovascular disease (CVD) risk reference values (< 1mg/L, low; 1–<3 mg/L, intermediate; ≥ 3mg/L, high).

Results
Mean CES-D, STAI scores, and hsCRP levels were 7.0 (SD = 5.9), 17.0 (SD = 5.7), and 3.84 (SD = 7.85), respectively. Generalized linear modeling, adjusted for sociodemographic characteristics revealed significant associations between depression (exp(β) = 1.12; p<0.01) and anxiety symptoms (exp(β) = 1.10; p<0.05) with continuous hsCRP levels. For categorical values of hsCRP, one SD increase in CES-D and STAI scores was associated with a 10% and 8% increase in the RRRs of high vs. low hsCRP, respectively. However, these relationships between CES-D or STAI and hsCRP were no longer statistically significant after adjustment for CVD risk factors and medications.

Conclusion
We found modest associations between anxiety and depressive symptoms and systemic inflammation measured by hsCRP among diverse Hispanics/Latinos that did not appreciably differ between heritage groups.
Gestational weight gain among pregnant women in Ibadan, Nigeria: Pattern, predictors and pregnancy outcomes
Authors: Adeoye Ikeola A. , Bamgboye Elijah A. , Omigbodun Akinyinka O. 
Published: August 2023

BackgroundGestational weight gain (GWG) is a risk factor for adverse pregnancy outcomes, future obesity and chronic diseases among women. However, has not received much attention in many low and middle-income countries such as Nigeria. We investigated the pattern, associated factors and pregnancy outcomes of GWG in Ibadan, Nigeria, using the Ibadan Pregnancy Cohort Study (IbPCS).MethodologyThe IbPCS is a multicentre prospective cohort study conducted among 1745 pregnant women recruited from four health facilities in Ibadan, Nigeria. GWG, the primary outcome, was categorised according to the Institute of Medicine’s classification into insufficient, adequate and excessive weight gain. Pregnancy outcomes were the secondary outcome variables. Logistic regression analysis (Adjusted odds ratios and 95% confidence interval CI) was used to examine associations, and Poisson regression analyses were used to investigate associations with outcomes.ResultsOnly 16.9% of women had optimal GWG, 56.8% had excessive GWG, and 26.9% had insufficient GWG. Excessive GWG was associated with high income ’> #20,000-’ (AOR: 1.64, 95% CI: 1.25–2.17), being overweight (AOR: 2.12, 95% CI: 1.52–2.95) and obese (AOR: 1.47, 95% CI: 1.02–2.13) after adjusting for confounders. In contrast, increased odds of insufficient GWG have associated women with depression (AOR: 1.70, 95% CI 1.17–2.47). There was no significant association between inappropriate GWG and pregnancy outcomes However, there was an increased odds for postpartum haemorrhage (AOR: 2.44, 95% CI 1.14–5.22) among women with obesity and excessive GWG.ConclusionsExcessive GWG was the most typical form of GWG among our study participants and was associated with high maternal income, and being overweight or obese. GWG needs to be monitored during antenatal care, and interventions that promote appropriate GWG should be implemented among pregnant women in Nigeria.
On distance-regular graphs Γ of diameter 3 for which Γ
3 is a triangle-free graph
Authors: Makhnev Aleksandr A. , Guo Wenbin 
Published: August 2023

Abstract
There exist well-known distance-regular graphs Γ of diameter 3 for which Γ
3 is a triangle-free graph. An example is given by the Johnson graph J (8, 3) with the intersection array {15, 8, 3;1, 4, 9}. The paper is concerned with the problem of the existence of distance-regular graphs Γ with the intersection arrays {78, 50, 9;1, 15, 60} and {174, 110, 18;1, 30, 132} for which Γ
3 is a triangle-free graph.
Demons and Forgetting in Etruscan Homeric Art
Authors: Tomanelli Lauren 
Published: August 2023

Abstract
This paper examines the inclusion of Etruscan demons such as Charun and Vanth in Homeric art, using the François Tomb as a case study. The combination of Greek and Etruscan figures is often described as a “patchwork” of influences. I argue that the “patchwork” approach is anachronistic and that fourth-century viewers would not have seen such a dichotomous opposition between Etruscan demons and Greek myths. Anthropological memory theory supplies a new framework for understanding the inclusion of Greek myths in the Etruscan pantheon. I argue that the François Tomb was the end product of a centuries-long process of forgetting: the Greek origin of the Homeric myths was no longer felt as acutely in the fourth century as when the two cultures first made contact. By the fourth century, the blending was not a calculated change or an attempt to show off foreign knowledge. It was a representation of the Etruscans’ own cultural memory, adapted over three centuries of Greek contact to become a syncretic system.
Study on the thermal stability and smoke suppressant effect of polyurethane foam modified by ammonium lignosulfonate
Authors: Zhang Xu , Yuan Dehe , Sun Simiao , Wang Zhi , Xie Hua , Su Zhanpeng 
Published: August 2023

Abstract
The modified polyurethane foam (PUF) with ammonium lignosulfonate was prepared by one-step water foaming method. The effects of ammonium lignosulfonate on its thermal stability and smoke suppression were investigated by thermogravimetric analysis, pyrolysis kinetics analysis, smoke density (Ds) and smoke toxicity analysis. The results showed that the addition of 15 % ammonium lignosulfonate (PUFA15) had the lowest mass loss of PUFs and the highest integral programmed decomposition temperature (870.8 °C). Its activation energy was the highest according to the Flynn-Wall-Ozawa method (110.1 kJ/mol), Kissinger method (181.1 kJ/mol), Starnk method (106.3 kJ/mol) and Coats-Redfern method (149.7 kJ/mol). In addition, PUFA15 had the lowest Ds (34.43) and the highest transmittance (66.74). This indicated that PUFA15 had good thermal stability and smoke suppression properties. The research results had a reference value for exploring the production of environmentally friendly PUF by biomass modification.
Hydrogelbasierte plasmonische Sensoren zur Ethanoldetektion: Einfluss des Quellverhaltens auf das optische Signal
Authors: Herzog Julia , Rio Marisa , Schuster Christiane , Härtling Thomas , Gerlach Gerald 
Published: August 2023

Zusammenfassung
Brechzahlsensitive plasmonische Sensoren mit nanostrukturierten Goldoberflächen bieten viele Vorteile für die kontinuierliche Vor-Ort-Überwachung in komplexen Prozessflüssigkeiten. In Kombination mit stimulus-responsiven Hydrogelen haben diese Potential für die selektive Detektion von Einzelparametern, hier der Ethanolkonzentration, bei sich gleichzeitig ändernden Stoffkonzentrationen anderer Komponenten. Ein erster Schritt zur Ausnutzung dieser selektiven Eigenschaften ist die Differenzierung des ethanolinduzierten Quelleffekts im eingesetzten Polyacrylamid-Hydrogel von der Brechzahländerung der zu analysierenden Flüssigkeit in Folge von Konzentrationsänderungen. Dies wurde durch die Anwendung einer mit Hydrogel funktionalisierten Messfläche und einer nicht funktionalisierten Referenzfläche erreicht. Das hier vorgestellte Sensorkonzept ermöglicht so die Bestimmung der Ethanolkonzentration wässriger Lösungen zwischen 40 und 60 vol%. Dabei wird gezeigt, dass von der Entquellung des Hydrogelvolumens nicht direkt auf das oberflächennahe Verhalten geschlossen werden kann, sondern eine individuelle Kalibrierung des optischen Signals notwendig ist.
Axon Initial Segment GABA Inhibits Action Potential Generation throughout Periadolescent Development
Authors: Lipkin Anna M. , Bender Kevin J. 
Published: August 2023

Neurons are remarkably polarized structures: dendrites spread and branch to receive synaptic inputs while a single axon extends and transmits action potentials (APs) to downstream targets. Neuronal polarity is maintained by the axon initial segment (AIS), a region between the soma and axon proper that is also the site of action potential (AP) generation. This polarization between dendrites and axons extends to inhibitory neurotransmission. In adulthood, the neurotransmitter GABA hyperpolarizes dendrites but instead depolarizes axons. These differences in function collide at the AIS. Multiple studies have shown that GABAergic signaling in this region can share properties of either the mature axon or mature dendrite, and that these properties evolve over a protracted period encompassing periadolescent development. Here, we explored how developmental changes in GABAergic signaling affect AP initiation. We show that GABA at the axon initial segment inhibits action potential initiation in layer (L)2/3 pyramidal neurons in prefrontal cortex from mice of either sex across GABA reversal potentials observed in periadolescence. These actions occur largely through current shunts generated by GABAAreceptors and changes in voltage-gated channel properties that affected the number of channels that could be recruited for AP electrogenesis. These results suggest that GABAergic neurons targeting the axon initial segment provide an inhibitory “veto” across the range of GABA polarity observed in normal adolescent development, regardless of GABAergic synapse reversal potential.Significance StatementGABA receptors are a major class of neurotransmitter receptors in the brain. Typically, GABA receptors inhibit neurons by allowing influx of negatively charged chloride ions into the cell. However, there are cases where local chloride concentrations promote chloride efflux through GABA receptors. Such conditions exist early in development in neocortical pyramidal cell axon initial segments (AISs), where action potentials (APs) initiate. Here, we examined how chloride efflux in early development interacts with mechanisms that support action potential initiation. We find that this efflux, despite moving membrane potential closer to action potential threshold, is nevertheless inhibitory. Thus, GABA at the axon initial segment is likely to be inhibitory for action potential initiation independent of whether chloride flows out or into neurons via these receptors.
Dietary Fiber and Microbiota Metabolite Receptors Enhance Cognition and Alleviate Disease in the 5xFAD Mouse Model of Alzheimer’s Disease
Authors: Zhou Yichen , Xie Liang , Schröder Jan , Schuster Iona S. , Nakai Michael , Sun Guizhi , Sun Yu B. Y. , Mariño Eliana , Degli-Esposti Mariapia A. , Marques Francine Z. , Grubman Alexandra , Polo Jose M. , Mackay Charles R. 
Published: August 2023

Alzheimer’s disease (AD) is a neurodegenerative disorder with poorly understood etiology. AD has several similarities with other “Western lifestyle” inflammatory diseases, where the gut microbiome and immune pathways have been associated. Previously, we and others have noted the involvement of metabolite-sensing GPCRs and their ligands, short-chain fatty acids (SCFAs), in protection of numerous Western diseases in mouse models, such as Type I diabetes and hypertension. Depletion of GPR43, GPR41, or GPR109A accelerates disease, whereas high SCFA yielding diets protect in mouse models. Here, we extended the concept that metabolite-sensing receptors and SCFAs may be a more common protective mechanism against Western diseases by studying their role in AD pathogenesis in the 5xFAD mouse model. Both male and female mice were included. Depletion of GPR41 and GPR43 accelerated cognitive decline and impaired adult hippocampal neurogenesis in 5xFAD and WT mice. Lack of fiber/SCFAs accelerated a memory deficit, whereas diets supplemented with high acetate and butyrate (HAMSAB) delayed cognitive decline in 5xFAD mice. Fiber intake impacted on microglial morphology in WT mice and microglial clustering phenotype in 5xFAD mice. Lack of fiber impaired adult hippocampal neurogenesis in both W and AD mice. Finally, maternal dietary fiber intake significantly affects offspring’s cognitive functions in 5xFAD mice and microglial transcriptome in both WT and 5xFAD mice, suggesting that SCFAs may exert their effect during pregnancy and lactation. Together, metabolite-sensing GPCRs and SCFAs are essential for protection against AD, and reveal a new strategy for disease prevention.Significance StatementAlzheimer’s disease (AD) is one of the most common neurodegenerative diseases; currently, there is no cure for AD. In our study, short-chain fatty acids and metabolite receptors play an important role in cognitive function and pathology in AD mouse model as well as in WT mice. SCFAs also impact on microglia transcriptome, and immune cell recruitment. Out study indicates the potential of specialized diets (supplemented with high acetate and butyrate) releasing high amounts of SCFAs to protect against disease.
More than annealing: RNAi is not alone in the fight against plant viruses
Authors: Lozano‐Durán Rosa 
Published: August 2023

Cellular organisms have evolved different strategies to defend themselves against the invasion by viruses. In plants, RNA interference (RNAi) or RNA silencing, which is triggered by virus‐derived double‐stranded (ds)RNA, is considered the main antiviral defence mechanism. Martínez‐Pérez et al have now uncovered an additional plant antiviral pathway, termed by the authors “m6A‐YTHDF axis,” which relies on the modification and subsequent recognition of the viral RNA.
Factors Associated With Attendance for Cardiac Neurodevelopmental Evaluation
Authors: Ortinau Cynthia M. , Wypij David , Ilardi Dawn , Rofeberg Valerie , Miller Thomas A. , Donohue Janet , Reichle Garrett , Seed Mike , Elhoff Justin , Alexander Nneka , Allen Kiona , Anton Corinne , Bear Laurel , Boucher Gina , Bragg Jennifer , Butcher Jennifer , Chen Victoria , Glotzbach Kristi , Hampton Lyla , Lee Caroline K. , Ly Linh G. , Marino Bradley S. , Martinez-Fernandez Yadira , Monteiro Sonia , Ortega Christina , Peyvandi Shabnam , Raiees-Dana Heather , Rollins Caitlin K. , Sadhwani Anjali , Sananes Renee , Sanz Jacqueline H. , Schultz Amy H. , Sood Erica , Tan Alexander , Willen Elizabeth , Wolfe Kelly R. , Goldberg Caren S. 
Published: August 2023

BACKGROUND AND OBJECTIVES
Neurodevelopmental evaluation of toddlers with complex congenital heart disease is recommended but reported frequency is low. Data on barriers to attending neurodevelopmental follow-up are limited. This study aims to estimate the attendance rate for a toddler neurodevelopmental evaluation in a contemporary multicenter cohort and to assess patient and center level factors associated with attending this evaluation.

METHODS
This is a retrospective cohort study of children born between September 2017 and September 2018 who underwent cardiopulmonary bypass in their first year of life at a center contributing data to the Cardiac Neurodevelopmental Outcome Collaborative and Pediatric Cardiac Critical Care Consortium clinical registries. The primary outcome was attendance for a neurodevelopmental evaluation between 11 and 30 months of age. Sociodemographic and medical characteristics and center factors specific to neurodevelopmental program design were considered as predictors for attendance.

RESULTS
Among 2385 patients eligible from 16 cardiac centers, the attendance rate was 29.0% (692 of 2385), with a range of 7.8% to 54.3% across individual centers. In multivariable logistic regression models, hospital-initiated (versus family-initiated) scheduling for neurodevelopmental evaluation had the largest odds ratio in predicting attendance (odds ratio = 4.24, 95% confidence interval, 2.74–6.55). Other predictors of attendance included antenatal diagnosis, absence of Trisomy 21, higher Society of Thoracic Surgeons-European Association for Cardio-Thoracic Surgery mortality category, longer postoperative length of stay, private insurance, and residing a shorter distance from the hospital.

CONCLUSIONS
Attendance rates reflect some improvement but remain low. Changes to program infrastructure and design and minimizing barriers affecting access to care are essential components for improving neurodevelopmental care and outcomes for children with congenital heart disease.
RESIGNIFICACIÓN DE PRACTICA DOCENTE EN EDUCACIÓN FÍSICA ESCOLAR: RETOS DEL PRESENTE SIGLO
Authors: BARROS CABARCAS YEIRO DAVID 
Published: August 2023

La contribución de este artículo de revisión está dirigida hacia el conocimiento de algunos aspectos relacionados con la profesión docente, más específicamente en el área de educación física que en su devenir ha reconfigurado sus prácticas acordes al tipo de hombre que en su momento histórico demande la sociedad vigente. En la actualidad existen muchos planteamientos desde distintos autores a cerca de este tipo de acciones que permiten relacionarlas con términos tales como educación, pedagogía, educación física, rol docente y didáctica. Resignificar, en sentido general y no solo para los profesores de educación física sino para todos, consiste en poseer capacidades pedagógicas, actitudes profesionales, personales y orientaciones filosóficas que contribuyan con el desempeño de su labor docente y la formación cognitiva, afectiva y en valores de sus estudiantes. Los aportes aquí consignados servirán como punto de partida para alcanzar el propósito principal de este escrito que está dirigido hacia la reflexión, en primera instancia, y a partir de ahí construya nuevas realidades durante su práctica profesional.
Niveles de inteligencia emocional en tiempos del sars cov-2 en estudiantes de primaria en el colegio parroquial san pancracio de soledad
Authors: Burgos Mancilla Feliciano , Medina Cardozo Ivonne Maritza 
Published: August 2023

Esta investigación tuvo como objetivo, determinar como en los tiempos del SARS COV-2 la salud emocional en los estudiantes del nivel primario se ha visto afectada desde su punto de vista socioafectivo y biológico. La investigación se realizó en el colegio parroquial San Pancracio de Soledad en la ciudad de Barranquilla Colombia durante el año 2021. La investigación realizada estuvo enmarcada en el paradigma empírico analítico, bajo un enfoque de tipo cuantitativo, y no experimental. Siendo el tipo de la investigación descriptivo con una muestra estructurada por 22 estudiantes pertenecientes a los grados 5to del Colegio en referencia. Así mismo como técnicas para la recolección de la información, se utilizó la encuesta tipo escala de Likert y, por último, para el análisis de la información, se tomó la estadística descriptiva. En relación con los resultados sobre el análisis de los niveles de inteligencia emocional, en atención a las situaciones emocionales durante los tiempos del SARS COV-2, fueron evaluados teniendo en cuenta tres criterios: atención emocional, claridad de sentimientos y reparación de emociones, lo que permitió establecer que las situaciones generadas en medio de la pandemia, arrojo como resultados niños malhumorados debido a las implicaciones del confinamiento obligatorio, sin ser capaces de buscar de manera cambiar dicho mal humor, apreciándose además, un muy bajo porcentaje de estudiantes que no presentaron una adecuada reparación de las emociones. Como conclusión se pudo establecer que el objetivo general sobre los niveles de inteligencia emocional de los estudiantes de 5to grado del Colegio Parroquial San Pancracio en tiempos de pandemia por SARS CoV-2, fue logrado, dando cuenta de la incidencia de la pandemia en la inteligencia emocional de los niños, permitió identificar que los educandos mostraron problemas relacionados con la capacidad para atender sus emociones, la claridad de sentimientos y la reparación de emociones, cuestiones que pueden ser un factor determinante para que los niños no se muestren resilientes ante situaciones de incertidumbre como la actual donde la pandemia puede generar sentimientos de miedo, estrés y ansiedad.
EFECTOS FISICOS EN ESTUDIANTES UNIVERSITARIOS DURANTE PANDEMIA COVID-19
Authors: TORRENEGRA ARIZA SILVIA ELENA 
Published: August 2023

El presente estudio tiene como objetivo describir los efectos físicos por el confinamiento
Obligatorio de estudiantes matriculados en la cátedra de deporte formativo en el semestre
2021-1 de la universidad del atlántico a causa de la pandemia mundial provocado por el
Virus COVID-19.
Con la finalidad de describir la manera en como estos estudiantes se encontraban luego de vivir el confinamiento obligatorio y mostrar que algunos de ellos poseen complicaciones tales como: bajos niveles de actividad física, altos niveles de masa corporal, alto consumo de alimentos altos en grasa, procesados que derivan en el desarrollo de enfermedades crónicas no trasmisibles, y finalmente alteraciones desde el punto de vista psicológico debido a los efectos del confinamiento obligatorio que tuvo el país durante de más de 6 meses. Aquí se representó una problemática que se hace palpable en los estudiantes que ingresan a la asignatura de deporte formativo, donde se evidencio diferentes problemas a raíz del periodo de aislamiento preventivo obligatorio por la pandemia COVID- 19 en cuanto a sus niveles de actividad física, ya que inicialmente estos estudiantes realizaban muy pocas actividades deportivas o que implicaran un mínimo esfuerzo, y debido al periodo de confinamiento esta condición empeoro de manera significativa en su condición física, ya que al estar en aislamiento sin posibilidades de salir se redujo potencialmente la mínima actividad física que estos estudiantes realizaban, de este modo género en ellos diferentes problemas tales como el aumento de peso excesivo que derivo en sobrepeso y obesidad. Esto dio lugar a problemas emocionales como la depresión, ansiedad y hasta tendencia al suicidio. De este modo, se evidencio las causas y las consecuencias que se dieron mayormente en estos estudiantes que variaron desde el entorno socioeconómico en el que se encuentran inmersos, como también la gran influencia de la sociedad y los medios de comunicación que día con día llevaron el reporte diario de la situación de la pandemia a nivel nacional y a nivel mundial.
Estudio descriptivo con un enfoque cuantitativo y paradigma empírico analítico y un diseño no experimental 250 estudiantes de la universidad del atlántico aplicando cuestionarios sobre medidas antropométricas (peso y talla) para obtener el índice de masa corporal (IMC)