bluuebunny/crossref_metadata_2025_split huggingface dataset:
Formulations of primer, acrylic paint and pastel in traditional Thai style colour
Authors:   , Kaew-on Nawarat 
Published: September 2023

This research aimed to improve Thai traditional primer, used for mural painting, with antibacterial property, to formulate novel primers having antibacterial behavior, scrub resistance and washability as well as to formulate paints according to Thai color dictionary. Both primers and paints were aimed to use in mural painting. We divided the research into 3 parts: 1) improved traditional primer and formulated novel primer with antibacterial, washable and scrub resistance properties; 2) formulated acrylic paints and pastels according to Thai color dictionary and 3) investigated the wavelengths used for distinguishing the change of paint caused by light, moist and heat using multi-spectrum imaging technique. Traditional primers that were made of natural constituents particularly tamarind glue and white clay hardly resist to environmental factors including the microorganisms because the natural components encourage their growth. Titanium dioxide, TiO2, and silver nanoparticles, AgNPs having antibacterial property, were used in the formulations. Subsequently they were tested against 4 bacterial species; Bacillus subtilis, B. cereus, B. mycoides, and Leclercia adecarboxylata that were found on the mural painting surface of Somanas Rajavaravihara temple in Bangkok, Thailand. The presence of TiO2 and AgNPs in the novel primers inhibited the growth of these 4 bacteria, while neither the traditional primer with AgNPs nor the one without showed inhibition activity against all 4 bacterial species. On the other hand, the novel formulated primers containing TiO2, aluminum silicates and AgNPs showed the best inhibition and the second best was the primer with aluminum silicates and AgNPs. The latter gave better scrub resistance and washability than the former. Primary colours were formulated, 11 colours for acrylic paint and 12 colours for pastel. These primary colours were used as database to formulate traditional Thai style colour for acrylic paint and pastel respectively. Samples of traditional Thai style colour were made, twenty colours for acrylic paint and forty colours for pastel. The color differences CIEDE2000 between the formulated and the Thai color dictionary’s CIELAB values were less than 3. The pass-fail color tolerance and brush testing were carried out by Thai artists. In addition, multi-spectrum imaging technique was employed to study the spectroscopic characterization of paints, pastel and primers that were influenced by changing of moist, heat and UV radiation.
Pathomechanism of x-linked osteogenesis imperfecta
Authors:   , Tongkobpetch Siraprapa 
Published: September 2023

Osteogenesis imperfecta (OI) or brittle bone disease is a genetic disorder characterized by deformities of bones and multiple bone fractures. We identified a new causative gene, MBTPS2, in two unrelated patients with OI inherited in X-linked pattern (X-OI). MBTPS2 or site-2 protease (S2P) is a protease that cleaves the transmembrane proteins to activate them acting as transcription factors. To determine pathomechanism of X-OI caused by MBTPS2 mutations, S2P functions were investigated. RNA and protein of S2P were stable. Instead, the defective S2P decreases its cleavage activities. ATF6 and CREB3L1 are target proteins of S2P. We demonstrated decreased a transcriptional activity of ATF6 and a decreased transcription factor form of CREB3L1. Both of them were resulted from defects in the cleavage activity of S2P. In addition, we generated iPSCs from patients’ skin fibroblasts and induced them to osteoblasts to elucidate the involving pathomechanism. During osteoblast differentiation, we found the delay or absence of calcium deposit and abnormal patterns of calcium binding in X-OI patients. Consistently, the studies of osteogenic gene expression revealed the defect of osteoblast differentiation and mineralization supporting the defects of calcium deposit. Interestingly, COL1A1, a downstream gene of CREB3L1, and SPARC, SEC23A, SEC24D and LOX, downstream genes of CREB3L3, were downregulated. These genes have functions involving in osteoblastogenesis. Taken together, we concluded that X-OI phenotype is possibly caused by the defects of osteoblast differentiation and mineralization resulting from the decreased transcriptional activities of CREB3L1 and CREB3L3 that downregulate COL1A1, SPARC, SEC23A, SEC24D and LOX.
Expatriate management, absorptive capacity of knowledge, and subsidiary performance : the case of Japan-based multinational companies in Thailand and Singapore
Authors:   , Ogushi Wataru 
Published: September 2023

The impact of expatriates on knowledge transfer in foreign subsidiaries has been a focus of research on knowledge management in multinational companies (MNCs). This study combines knowledge-based view, the concept of absorptive capacity, and studies on expatriates literature’s approach to examine the effect from expatriates on transfer of two kinds of MNC’s knowledge (i.e. technological knowledge and marketing knowledge). This paper also analyzes the impact of knowledge absorptive capacity on subsidiary performance to examine how expatriates affect subsidiary performance by knowledge transfer. This study ran analysis of 33 subsidiaries of Japan-based firms in Thailand and Singapore over a 16-year period. Results of analysis indicate that the composition of expatriates in subsidiary workforce 1: promotes absorptive capacity on technological knowledge of subsidiary, but 2: hinders absorptive capacity on marketing knowledge of subsidiary. In addition, absorptive capacity of two kinds of knowledge in subsidiary 3: does not gain subsidiary performance by working separately, but 4: gain subsidiary performance by working together. The implications for expatriate management study and knowledge transfer literature are discussed.
Gold nanoparticles in CLP model and mechanism in bone marrows derived macrophages cell for sepsis severity attenuation
Authors:   , Taratummarat Sujittra 
Published: September 2023

Sepsis is still a major worldwide- public health problem as a leading cause of the high mortality rate condition. Sepsis is the inflammatory condition in host due to bacterial infections. Sepsis severity depends on the individual's immune responses and the organism virulence factor. The current strategies for sepsis treatment are based, mainly on, symptomatic treatment with antibiotics. However, the adjuvant therapy in sepsis is interesting. Gold nanoparticles are anti-inflammatory drug from the ancient time which is still currently used for the treatment of rheumatoid arthritis. Thus, we hypothesized that gold nanoparticles could be effective in reducing an inflammation in sepsis and testes in bone marrow (BM)-derived macrophages (in vitro) and cecal ligation and puncture (CLP) mouse model (in vivo). After treat with gold nanoparticles, the pro-inflammatory cytokines (TNF-α, IL-1β and IL-6) was reduced in both in vitro and in vivo. But, the anti-inflammation cytokine (IL-10) was increased in vitro but decreased in vivo. However, CLP mice showed the higher survival rate with gold nanoparticles treatment. the bactericidal property and the M2 macrophages induction property of gold nanoparticles are also demonstrated. In conclusion, gold nanoparticles attenuated sepsis through the immune modulation and bactericidal activity. Further studies on the mechanisms and the translation to patients are interesting.
Effects of curcumin on oxidative stress, inflammation and apoptosis in L-arginine induced acute pancreatitis in mice
Authors:   , Chingchit Thidarat 
Published: September 2023

L-arginine (L-arg) is an amino acid that has been used to induce acute pancreatitis (AP) in mice. Curcumin is an active ingredient constituent of rhizomes of the plant Curcuma longa Linn. It has been used for the treatment of inflammatory conditions and shown to exhibit a variety of biological activities such as anti-inflammatory and anti-oxidant. The present study aims to examine the effects of curcumin on oxidative stress, inflammation and apoptosis in AP. Male ICR mice were randomly divided into 4 groups. 1) Control group, mice will be received i.p. of 1% DMSO as a vehicle. 2) AP group, mice will be received two i.p. of L-arg 450 mg/100 g BW at an interval of 1 h apart. 3) AP + low dose curcumin group, mice will be received curcumin 50 mg/kg bw by i.p. 1 h before L-Arg injection and then once daily for 3 days. 4) AP + high dose curcumin group, mice will be received curcumin 200 mg/kg bw by i.p. 1 h before L-Arg injection and then once daily for 3 days. The mice were sacrificed at 72 h. The pancreatic tissue was fixed for histological evaluation and for NF-kB, apoptosis and MPO immunohistochemistry. The second part was frozen until using protein extraction for 4-HNE examination. Blood sample will be collected for amylase analysis. In AP group, body weight was significantly reduced than control group. While in curcumin group, body weight was maintained. The serum amylase, number of MPO positive cells, NF-kB positive cells, TUNEL positive cells, and 4-HNE expression were increased significantly in AP group when compared with control group, while decreased in low and high dose of curcumin group. Moreover, the AP group showed inflammation, edema and fat necrosis of severe activity of AP. While curcumin low and high dose group showed significantly attenuating histopathological score. However, there is no significant difference between low and high dose of curcumin. In conclusion, curcumin could attenuate AP via anti-oxidant, anti-inflammation and anti-apoptosis property leading to improve pancreatic damage.
Carotenoids and metabolism of the green microalga Chlorococcum sp. 8367RE under stress conditions
Authors:   , Janchot Kantima 
Published: September 2023

Green microalgae are one of the natural resources for productions of various and beneficial bioactive compounds, such as UV-screening compounds and carotenoids. This study focuses on the changes of carotenoids and metabolisms in the green microalga Chlorococcum sp. 8367RE under stress conditions. The results showed that stresses by salt, light, drought, and nitrogen starvation affected on alterations of morphological characteristics. Interestingly, size of cells culturing under salt stresses dramatically increased. It should be noted that KCl stress caused the enlargement of cell sizes approximately 5 folds. Carotenoids were identified and quantified by using ultra-high performance liquid chromatography (UHPLC) and mass spectrometry. Three kinds of carotenoids namely violaxanthin, antheraxanthin and lutein were found in algal extracts culturing under control condition. Among these carotenoids, lutein was detected as the highest content 2.24 μg/mg DW. Upon KCl stress, two types of carotenoids; astaxanthin and canthaxanthin, were additionally identified. It is noteworthy that this stress condition, lutein content was very similar level as control while astaxanthin was accumulated 0.12 μg/mg DW. For nitrogen starvation, total carotenoids were decreased. Furthermore, fatty acids, proteins, amino acids, and carbohydrates were analyzed. KCl stress and nitrogen starvation led to the increment of fatty acids contents approximately 2 times (12.79 ± 0.03% DW) and 4 times (28.07 ± 0.79% DW), respectively. Oleic acid was found to be the predominant fatty acid. This study indicates that salt stress resulted in the remarkable alteration of cells morphology and the enhancement of valuable secondary carotenoids and omega-9 fatty acid accumulation. These would be advantageous in health and nutraceutical industries.
Comparison of the accuracy of surgical guided template produced from intraoral scan technique and model scan technique for implantation using computer assisted implant surgery
Authors:   , Kiatkroekkrai Prudsaporn 
Published: September 2023

Objectives: To compare the accuracy of implant position placed by CAIS technique using surgical guided template produced by intraoral scan and model scan.

Materials and methods: Patients who needed single tooth implant restoration were enrolled in this study and devided into two groups randomly according to the surface scan technique (n=30 each group). Intraoral scans were done using the Trios Scanner (3shape). While, diagnostic casts were scanned by D900L lab scanner (3shape). The templates were design by the clinician using coDiagnostiX software (Dental Wings Inc.). Implant surgery were performed according to fully CAIS protocol. CoDiagnostiX software was used to compare the deviations between planned and placed implant.

Results: Total of 60 implants were treated. The average angular deviation was 2.41°±1.48° and 3.23°±2.09°, the average 3D deviation at platform was 0.87±0.49 mm and 1.01±0.53 mm, while, the average 3D deviation at apex was 1.10±0.53 mm and 1.38±0.68 mm for intraoral scan group and model scan group respectively. Nevertheless, there was no statistically significant difference between groups (P > .05).

Conclusion: The results of this study demonstrated that the accuracy of intra-oral scan technique was similar to model scan technique in all implant dimensions and axis for computer assisted implant surgery.
CD103+ tissue resident memory T cells in oral lichen planus
Authors:   , Amnuaiphanit Phisut 
Published: September 2023

Oral lichen planus (OLP) is a chronic inflammatory disease that results from a disorder of infiltrating T cells. Tissue resident memory T cells (TRM cells) are CD103-expressing T cells that persist within previously inflamed oral mucosa in the long term to provide locally rapid defensive responses against encountered pathogens. They are also speculated to be associated with some diseases including OLP. This study aimed to determine the number and the proportion of CD103+ TRM cells in the OLP lesions as compared to the normal mucosa. Immunohistochemical study of CD3+, CD4+, CD8+ and CD103+ cells in 15 OLP tissues and 15 normal mucosa tissues was performed. An unpaired t-test, a paired t-test, a Mann-Whitney U test and a Wilcoxon Signed Ranks test were used to analyze the data. A p-value < 0.05 was considered statistically significant. The results revealed significant increases in the numbers of CD3+, CD4+, CD8+ and CD103+ cells per area (cells/mm2) in the OLP lesions as compared to the normal mucosa (p < 0.001). These cells were frequently expressed in the lamina propria rather than the epithelium (p < 0.005). The proportion of CD103+ cells to CD3+ cells (%) in the lamina propria of the OLP lesions was lower than that of the normal mucosa. (p < 0.001), but this significant difference was not found in the epithelium between both tissues (p = 0.062). Furthermore, the OLP lamina propria showed lower proportion of CD103+ cells to CD3+ cells than the OLP epithelium (p < 0.001). In conclusion, this study demonstrates the several-fold increase in the density of CD103+ cells in the OLP lesions that may suggest the association between CD103+ TRM cells and the pathogenesis of OLP.
Anatomical and biomechanical factors associated with plantar fasciitis in Thai male conscripts
Authors:   , Harutaichun Pavinee 
Published: September 2023

Etiology of plantar fasciitis among novice conscripts is multifactorial. The combination of all potential factors should be included for multivariate analysis to determine the significant predictors. The present study aimed to identify the intrinsic predictors of plantar fasciitis among novice conscripts. Two hundred and seventy healthy male conscripts who were without lower back or lower extremity pain prior to the commencement of military training were participated in this study. Intrinsic predictors which included individual, anatomical, and biomechanical variables were assessed at baseline. After 10 weeks of training, 113 participants were assessed again and classified as having (n = 71) or not having (n = 42) plantar fasciitis. Multiple logistic regression was used to identify significant predictors. The primary criterion variable was the presence or absence of plantar fasciitis. Current results indicated that the conscripts with poorer quality of movement were two times more likely to exhibit plantar fasciitis (OR = 1.996). The conscripts with more femoral anteversion angle decreased the risk of presenting with plantar fasciitis (OR = 0.720). Regarding individual component, the conscripts with higher body mass index and more stress level increased more risk of plantar fasciitis (OR = 1.238 and 1.110, respectively). In addition, the conscripts with higher physical exercises level before military program reduced the risk of presenting with plantar fasciitis (OR = 0.242). In conclusion, multiple factors – especially individual characteristics and the abnormalities from proximal region (other than foot and ankle) – contributed to the prediction of the development of plantar fasciitis among Thai conscripts.
Biomechanics of sit-to-stand and stand-to-sit in typical children aged 4 - 12 years and young adults
Authors:   , Mapaisansin Potjanun 
Published: September 2023

The aim of study is to investigate the biomechanical pattern of sit-to-stand and stand-to-sit movement in children aged 4 to 12 years and young adults. Seventy-six participants were separated into 4 groups as following: (1) 18 children aged 4-6 years; (2) 19 children aged 7-9 years; (3) 20 children aged 10-12 years; (4) 19 adults aged 18-25 years. All participants performed their preferred pattern of sit-to-stand and stand-to-sit movement. The results showed that two patterns of sit-to-stand movement were found including sit-to-stand with and without feet moving backward. Children performed sit-to-stand with and without feet moving backward while adults only performed sit-to-stand with feet moving backward. The proportion of children who did sit-to-stand with feet moving increased as the children were older. For sit-to-stand movement, children aged 4 to 9 years completed the task faster than children aged 10 to 12 years and adults. Children aged 4 to 9 years moved trunk forward faster and had more hip flexion than children aged 10 to 12 years and adults. Moreover, the maximum knee extension moments in children aged 4 to 9 years were less than adults. For stand-to-sit movement, children aged 4 to 9 years showed less knee flexion than adults. In addition, the children aged 4 to 9 years showed lower maximum knee extension and ankle dorsiflexion moments as compared to adults. Therefore, the children aged 10 years and older would perform sit-to-stand and stand-to-sit movement like adults. This information was useful to help the clinicians to assess and interpret the sit-to-stand and stand–to-sit capability of the children to see how their performance deviated from the typical children. Moreover, this information can be used as the supporting document for clinical decision making in order to apply an appropriate treatment.
Plasma characteristics and ion etching performance in hard disk drive slider fabrication processes
Authors:   , Wongpanit Napakan 
Published: September 2023

A hard disk drive (HDD) is the permanent magnetic data storage and one of the most important components of computers, electronic devices and cloud data storage service facility. The data reading and writing are operated by the reader and writer parts of HDD head or slider. These reader and writer were made of multilayer thin ilms of different materials, forming a tunneling magnetoresistive (TMR) device. In HDD production, the ion beam etching (IBE) process was used in the preparation of surface patterns and cleaning in many fabrication steps. The Monte Carlo-based simulation package, SRIM was applied to calculate the etching yields and %energy loss of those materials in the TMR structure. The calculation showed that the etching yields of materials reach the maximum value, at an incident angle of 70° to the normal surface. The total etching yields of compounds were calculated from the etching yield of each element. The plasma characterization in an industrial-size IBE system has been performed to extract the plasma characteristic at different process conditions. The effects of process parameters in IBE system such as incident beam angle, ion beam current and gas flow in the system were analyzed. The floating potential of plasma in this IBE system with the electron compensation from a plasma bridge neutralizer (PBN) is 3 V, while the plasma potential is 2.5 V. The ion current densities in the actual system and the etching rate of different TMR materials were calculated.
Tribological characterization of lapping lubricant in hard disk drive fabrication
Authors:   , Jitphayomkun Sawanee 
Published: September 2023

One of the most important processes in hard disk drive fabrication is the lapping process. As two bodies are in contact, the friction occurs, and the softer material can be worn out by the harder. By using lubricant in the lapping process, it does not only reduce the friction, but it also transfers heat and captures debris away from the surface contacts. This thesis work focused on the effects of tribological parameters toward the characteristics of lubricants, using ball-on-disk tribometer. The tribological behaviors between using different base lubricants were investigated. At the same condition as final lapping process, EG-based and oil-based lubricants exhibited the average coefficient of friction (after 100 contact cycles) at about 0.089± 0.115 and 0.023±0.012, respectively. These values were much lower than without lubricants. Scanning electron microscopy results confirmed deeper and wilder wear tracks on dry lubricant than those with lubricants. Dry surface exhibited the boundary regime, which the normal load and sliding speed has no influence on its friction regime. By using oil-based lubricant, the friction regime transited from mixed to boundary regime, as the normal load increased. Applying EG-based lubricant, the friction regime transited from mixed for lower sliding speed to hydrodynamic regime for higher sliding speed at 0.1N but transited from mixed regime to boundary regime at 0.5N instead. Moreover, the effects of adding additives in EG based lubricant were also studied. It was found that by added surfactant on EG-based lubricant its friction belongs to boundary regime. While added corrosion inhibitors its friction belongs to mixed regimes.