bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diet supplemented with olive cake as a model of circular economy: Metabolic and endocrine responses of beef cattle
Authors: Bionda Arianna , Lopreiato Vincenzo , Crepaldi Paola , Chiofalo Vincenzo , Fazio Esterina , Oteri Marianna , Amato Annalisa , Liotta Luigi 
Published: December 2022

IntroductionIntegrating by-products into livestock diet represents a great opportunity for implementing the concept of circular economy while reducing feed costs. Olive cake (OC) is considered an agro-industrial waste, but the high content of valuable metabolites makes it a promising feed integration. Therefore, this study investigated the effect of OC integration in beef cattle diet on different blood parameters.MethodsForty-eight young growing fattening Limousines-−24 bulls (body weight 350 ± 15 kg) and 24 heifers (280 ± 10 kg)—, aged 240 ± 20 days, were randomly allocated to 1 of 3 dietary treatments: concentrate at 0% (Control group: CTR), 10% (Low-olive cake group: L-OC), or 15% (High-olive cake group: H-OC) of OC inclusion. Blood samples and body weights were collected before administrating the supplemented diet (0 d), at the end of the stocker growing phase (56 d), and at the end of the fattening (147 d). After being slaughtered, animal carcasses were weighted. A linear regression model was fitted for each blood parameter with the 0 d as covariate and diet, time, sex, diet × time, and diet × sex as fixed effects.ResultsIn males, body weight was highest in CTR, but carcass weight was similar in all the groups. All the blood parameters were within physiological ranges, independently from the animal diet. CTR group showed the highest alanine aminotransferase (ALT, P = 0.0027) and creatine kinase (P = 0.0119), whereas total bilirubin (P = 0.0023) was higher in H-OC than in CTR. Moreover, ALT was highest in CTR at 56 d, becoming similar in all the groups at 147 d (P = 0.0280). Instead, the increase observed in total cholesterol from 56 to 147 d was lower in H-OC compared with CTR and L-OC (P = 0.0451). A significant effect of diet × sex interaction was observed on triglycerides, urea, liver enzymes, and insulin. These data support the OC inclusion of up to 15% of the concentrate with no detrimental effect on beef cattle metabolic status.DiscussionIn conclusion, OC can be considered as a component in beef diet giving an opportunity to improve agriculture sustainability.
The sylvian keyhole approach for surgical clipping of middle cerebral artery aneurysms: Technical nuance to the minipterional craniotomy
Authors: Rychen Jonathan , Saemann Attill , Gehweiler Julian E. , Roethlisberger Michel , Soleman Jehuda , Hutter Gregor , Müller-Gerbl Magdalena , Mariani Luigi , Guzman Raphael 
Published: December 2022

BackgroundThe minipterional (MPT) craniotomy is a workhorse approach for clipping of middle cerebral artery (MCA) aneurysms. Because it aims to reach the skull base, traction on the temporal muscle is required. As a result, patients may suffer from transient postoperative temporal muscle discomfort. The sylvian keyhole approach (SKA) represents an alternative craniotomy for the clipping of MCA aneurysms. The aims of this study are to describe the operative technique of the SKA and to discuss the benefits and disadvantages compared to the MPT craniotomy.MethodsIn this technical note, we report the experience gained with the SKA. This experience was acquired with virtual reality, 3D-printed models, and anatomical dissections. We also present two clinical cases.ResultsThe SKA is centered on the distal sylvian fissure and tailored toward the specific MCA aneurysm. Traction to the temporal muscle is not necessary because access to the skull base is not sought. With the SKA, dissection of the MCA is performed from distal to proximal, aiming for a proximal control at the level of the M1-segment. The limen insulae was identified as a key anatomical landmark for approach selection. The SKA offers good surgical maneuverability when the aneurysm is located at the level or distal to the limen. The MPT craniotomy, however, remains the most appropriate approach when the aneurysm is located proximal to the limen.ConclusionThe SKA represents a feasible and innovative alternative approach to the MPT craniotomy for surgical clipping of unruptured MCA aneurysms located at the level or distal to the limen insulae.
Intra-osseous infiltration of adipose mesenchymal stromal cells and plasma rich in growth factors to treat acute full depth cartilage defects in a rabbit model: Serum osteoarthritis biomarkers and macroscopical assessment
Authors: Torres-Torrillas Marta , Damiá Elena , Peláez Pau , Miguel-Pastor Laura , Cuervo Belén , Cerón José J. , Carrillo José M. , Rubio Mónica , Sopena Joaquín J. 
Published: December 2022

IntroductionIntra-articular infiltration of plasma rich in growth factors (PRGF) and adipose mesenchymal stromal cells (AMSCs) are known to inhibit osteoarthritis progression. However, in severely affected patients, the treatment cannot reach the deeper layers of the articular cartilage; thus, its potential is limited. To overcome this limitation, intra-osseous infiltrations have been suggested. The purpose of this study is to assess the impact of intra-osseous infiltration therapies on serum biomarkers of osteoarthritis and to assess cartilage regeneration macroscopically.Materials and methodsA total of 80 rabbits were divided into four groups based on the intra-osseous treatment administered on the day of surgery: control, PRGF, AMSCs and a combination of PRGF + AMSCs. In addition, all groups received a single intra-articular administration of PRGF on the same day. Serum biomarker levels were measured before infiltration and 28-, 56-, and 84-days post infiltration, and macroscopical assessment was conducted at 56- and 84-days follow-up post infiltration.ResultsIn the PRGF + AMSCs group, significantly lower concentrations of hyaluronic acid and type II collagen cleavage neoepitope were recorded at all time points during the study, followed by PRGF, AMSCs and control groups. Regarding macroscopical assessment, lower scores were obtained in PRGF + AMSCs group at all study times.DiscussionThe results suggest that the combination of intra-articular PRGF with intra-osseous PRGF or AMSCs achieves better results in rabbits with acute chondral defects and that intra-osseous infiltration is a safe procedure.
Life Long Learning Preferences of General Surgeons After Covid-19 : Hybrid Model
Authors: EKİCİ Mehmet Fatih , YILDIRIM Ali Cihat , ZEREN Sezgin 
Published: December 2022

Aim:
For a surgeon during his professional career; Increasing their knowledge and experience, improving their professional skills and sharing their knowledge and experience is a necessity rather than a choice. The COVID-19 pandemic has revealed new choices in the concept of lifelong learning, with virtual meetings scheduled by surgeons using videoconferencing applications over the internet. In this study, we evaluated the compliance of general surgeons to webinars during the COVID-19 outbreak and their future training expectations with a questionnaire.
Design:
A questionnaire of 20 questions was prepared. The questionnaire was administered questions without aiming to obtain the personal information of the participants. . This survey was announced on the social media application Twitter. Survey questions were answered by 108 participants.
Results:
In the survey participated by surgeons, we concluded that short-term presentations, edited surgery videos and question-answer activities will be preferred more, and webinars held in the evening will be preferred more than those planned at the weekend. During the pandemic, it was determined that surgeons preferred free webinars and attended more national and international meetings compared to the pre-pandemic period. Respondents stated that they would prefer hybrid meetings in the future.
Results:
Considering the results of our social media-mediated survey: there is an intense participation in online seminars by surgeons. We also concluded that in the near future, surgeons will prefer hybrid training models rather than face-to-face training to improve and update themselves.
Pemanfaatan Limbah Jerami, Sekam, dan Urine Sapi sebagai Pupuk Organik untuk Meningkatkan Pertumbuhan dan Produksi Padi
Authors: Istiqomah Istiqomah , Eka Kusumawati Dian , Dita Serdani Army , Abdul Choliq Fery 
Published: December 2022

Rice cultivation activities can produce organic waste such as straw and husks which can be processed into solid organic fertilizer and liquid smoke. In addition to agricultural waste, organic material from livestock waste can also be used as organic fertilizer, one of which is cow urine which can be processed into cow biourine. This research aimed to determine the effect of organic fertilizer from straw, husk and cow biourine on the growth and production of rice. The research used factorial randomized block design (RAKF) with 2 factors. The first factor is solid organic fertilizer which consists of treatment without solid organic fertilizer, straw ash, and rice husk biochar. The second factor is liquid organic fertilizer which consists of treatment without liquid fertilizer, cow biourine, and husk liquid smoke. The observed parameters were plant height, number of tillers, leaf chlorophyll content, number of panicles, weight of 1000 seeds, and weight of grain per hectare. The results showed that there was an interaction between solid organic fertilizer (rice husk biochar and straw ash) and liquid organic fertilizer (husk liquid smoke and cow biourine) in increasing plant height, number of tillers, number of panicles, and yields. Separate treatment of solid organic fertilizer and liquid organic fertilizer affected the leaf chlorophyll content of rice plants. The application of rice husk biochar and cow biourine fertilizer resulted in the highest plant height, number of tillers, and number of panicles. In rice yields, the highest yields were found in rice husk biochar combined with cow biourine and husk biochar combined with husk liquid smoke.
BGEM™: Assessing Elevated Blood Glucose Levels Using Machine Learning and Wearable Photo plethysmography Sensors
Authors: Shi Bohan 
Published: December 2022

<p>Diabetes mellitus (DB) is the most challenging and fastest-growing global public health challenge. An estimated 10.5% of the global adult population has been suffering from diabetes, and almost half of them are undiagnosed. The growing at-risk population further exacerbated the scarce health resources where the adults worldwide with impaired glucose tolerance (IGT) and impaired fasting glycaemia (IFG) were estimated at around 10.6% and 6.2%, respectively. All the current diabetes screening methods are invasive and opportunistic and must be conducted in a hospital or a laboratory by trained professionals. At-risk subjects might remain undetected for years and miss the precious time window for early intervention in preventing or delaying the onset of diabetes and its complications. This study was conducted at KK Women's and Children's Hospital of Singapore, and five hundred participants were recruited (mean age 38.73 $\pm$ 10.61 years; mean BMI 24.4 $\pm$ 5.1 kg/m\textsuperscript{2}). The blood glucose levels, for most participants, were measured before and after 75g of sugary drink using both the conventional glucometer (Accu-Chek Performa) and the wrist-worn wearable. The results obtained from the glucometer were used as the ground truth measurements. We propose leveraging photoplethysmography (PPG) sensors and machine learning techniques to incorporate this into an affordable wrist-worn wearable device to detect elevated blood glucose levels ($\geqslant 7.8 mmol/L $) non-invasively. Multiple machine learning models were trained and assessed with 10-fold cross-validation using subject demographic data and critical features extracted from the PPG measurements as predictors. Support vector machine (SVM) with a radial basis function kernel has the best detection performance with an average accuracy of 84.7%, a sensitivity of 81.05%, a specificity of 88.3%, a precision of 87.51%, a geometric mean of 84.54% and F-score of 84.03%. Hence, PPG measurements can be utilized to identify subjects with elevated blood glucose measurements and assist in the screening of subjects for diabetes risk.</p>
Fully Digital Second-order Level-crossing Sampling ADC for Data Saving in Sensing Sparse Signals
Authors: Renteria-Pinon Mario , Tang Xiaochen , Ramirez-Angulo Jaime , TANG WEI 
Published: December 2022

<p>This paper presents a fully integrated second-order level-crossing sampling data converter for sensing sparse signals with real-time detection of turning points. Compared with con- ventional level-crossing sampling ADCs which sample at fixed voltage levels, the proposed circuits update tracking thresholds using linear prediction, which forms sloped sampling levels. The prediction and calculation are done digitally by modifying the digital control logic of a conventional SAR ADC. The system sepa- rates the sampling and quantization processes and only selects the turning points in the input waveform for quantization. The output of the proposed data converter consists of both the quantized amplitudes of the selected sampling points and the timestamps between the selected sampling points. The main advantages of the proposed circuits are data savings and power savings for the following digital signal processing or communication circuits. The test chip was fabricated using a 180nm CMOS process. When sensing sparse signals such as ECG signals, the proposed ADC saves 30% compared to a conventional SAR ADC with an equal quantizer resolution and achieves a compression factor of 6.17. </p>
Rekonstruksi Kasus Penyelesaian Nusyuz Dalam Undang Undang Keluarga Islam Indonesia Dan Malaysia
Authors: Amanuddin Muhammad 
Published: December 2022

Latar Belakang : Hukum keluarga merupakan hukum yang sedang dan masih terus mendapat perhatian besar dari negara negara muslim di dunia, termasuk di belahan asia tenggara ,yaitu negara Indoneisia dan Malaysia, negara dalam hal ini merasa perlu melindungi hak-hak hukum dari warga negaranya dengan melegeslasi beberapa hukum yang berkaitan dengan kepentingan warga negaranya. Salah satu hukum keluarga yang sudah di legeslasi oleh negara Indonesia dan Malaysia adalah hukum yang berkaitan dengan nusyuz dimana untuk di Indonesia dapat dilihat dalam Kompilasi Hukum Islam, Undang undang No : 1 tahun 1974 tentang perkawinan , sementara di Malaysia telah melegeslasi hukum yang berkaitan dengn nusyuz dalam enakmen enakmen di seluruh negara bagian Malaysia, termasuk di negaera wilayah persekutuan.
Tujuan : Dengan demikian, seorang istri dapat dikatakan nusyuz jika ia tidak mau berbakti, baik secara lahir maupun batin kepada suaminya dalam hal yang dibenarkan oleh hukum Islam. Selanjutnya. Pasal 84 KHI berbunyi Istri dapat di anggap nusyuz jika ia tidak mau melaksanakan kewajiban-kewajiban.
Metode : Methode Penelitian dalam pembahasn ini adalah penelitian kepustakaan (library metode), yakni dengan membaca dan mengkaji Undang undang dan buku buku serta kitab kitab yang berkaitan dengan pembahasan nusyuz.
Hasil : Dihasilkan dalam perundang-undangan ternyata juga terjadi perbedaan, maka menjadi penting untuk di bahas sebagai suatu kajian terhadap Undang-undang Keluarga Islam Di Indonesia dan Malaysia.
Kesimpulan: Dengan konstruksi hukum nusyuz di Indonesia dan Malaysia tersebut memunculkan berbagai permasalahan dalam menyelesaiakan nusyuz di pengadilan agama di Indoneisa, maupun di Mahkahamah syari’ah di Malaysi, oleh Karena itu perlu rerkonstruksi ulang tentang hal tersebut berupa klousul Malaysia dalam Undang undang Hukum Keluarga Islam, baik di Indonesia maupun di Malaysia.
Totemisme di Era Modernisasi: Realitas Masyarakat Adat Manggokal Holi pada Etnis Simalungun Sumatera Utara
Authors: Silalahi Bonita Silalahi , Nur Shahida Lela , Jhontua Dionisius P Matheus 
Published: December 2022

Latar Belakang : Dalam masyarakat yang tinggal di daerah pedesaan, totemisme adalah penggambaran kehidupan manusia di mana tumbuhan dan hewan tertentu dianggap suci. mengacu pada temuan Durkheim tentang totemisme, yang menggambarkan sistem keagamaan yang paling sederhana dan primitif serta simbol organisasi sosial orang tertentu, klan.
Tujuan : Metode penelitian yang bertujuan menemukan dan menggambarkan secara naratif aktivitas, tindakan, dan efek manusia sepanjang hidup mereka. Dalam Rukajat (2018), Creswell (2010) menjelaskan bahwa tujuan penelitian kualitatif adalah memasukkan informasi tentang partisipan penelitian serta fenomena yang diselidiki.
Metode : Menjelaskan bahwa penelitian kualitatif merupakan tradisi tertentu dalam ilmu-ilmu sosial yang pada dasarnya bergantung pada pengamatan terhadap kehidupan manusia. , baik dalam bidang atau peristiwa dengan cara mengidentifikasi item-item yang relevan dengan berbagai kondisi manusia, dunia, tindakan, kepercayaan, dan kepentingan dengan fokus pada perbedaan sehingga menghasilkan jawaban.
Hasil : Praktik totemisme masyarakat simalungun dengan memaknai totemisme sebagai representasi dari tradisi mangokal holi Ketika kelompok-kelompok soa bergabung menjadi satu desa atau negara, masing-masing tuang belulang menyimpan totemismenya sendiri.
Kesimpulan: Modernisasi telah menyentuh realitas kehidupan masyarakat adat simalungun. Bentuk perubahannya mengikuti perkembangan ilmu pengetahuan dan teknologi dalam berbagai aspek, antara lain pendidikan.
Pemetaan Cakupan Pengguna KB Aktif Dan Unmet Need Di Kabupaten Ponorogo Tahun 2021
Authors: Bella Dwi Saputri  , Diah Indriani  
Published: December 2022

Keluarga Berencana bertujuan untuk mengontrol jumlah penduduk dengan membatasi jumlah anak setiap keluarga untuk mencapai kesejahteraan keluarga. Program tersebut dilakukan dengan menghimbau Pasangan usia subur untuk menggunakan kontrasepsi misalnya intrauterine device, metode operasi pria, metode operasi wanita, implan, kondom, pil, atau suntik. Pada tahun 2021, Kabupaten Ponorogo mengalami penurunan cakupan pengguna keluarga berencana aktif sekaligus peningkatan prevalensi unmet need. Sistem Informasi Geografi merupakan ilmu yang mempelajari pembuatan peta secara komputasi atau biasa disebut dengan pemetaan. Pemetaan dilakukan untuk memantau capaian cakupan pengguna keluarga berencana aktif dan unmet need setiap wilayah kecamatan di Kabupaten Ponorogo. Penelitian ini merupakan penelitian deskriptif yang menggambarkan pengguna keluarga berencana aktif dan unmet need di Kabupaten Ponorogo. Penelitian ini menggunakan data sekunder yang selanjutnya akan dianalisis secara spasial. Hasil penelitian menunjukkan bahwa terdapat 4 kecamatan yang memiliki cakupan pengguna keluarga berencana aktif dibawah capaian Kabupaten Ponorogo dan terdapat 9 kecamatan dengan prevalensi unmet need diatas capaian Kabupaten Ponorogo. Metode kontrasepsi yang paling diminati oleh masyarakat Kabupaten Ponorogo adalah suntik. Analisis kluster berdasarkan cakupan KB Aktif dan unmet need membagi Kabupaten Ponorogo menjadi 4 kluster. Hasil pemetaan yang telah dilakukan, dapat menjadi bahan pertimbangan untuk meningkatkan keberhasilan Program Keluarga Berencana di Kabupaten Ponorogo.
POTENSI ANTIBAKTERI EKSTRAK DAUN UBI JALAR UNGU (Ipomea batatas L.) TERHADAP BAKTERI GRAM NEGATIF DENGAN METODE BROTH MICRODILUTION
Authors: Aliyah Siti Hamidatul 
Published: December 2022

Abstract
Indonesia has wide cultivation of purple sweet potatoes (Ipomea batatas L.) commodities, particularly in Jambi province. However, the difference of phytochemical profiles in purple sweet potatoes among geographical regions has not been fully explored. The objective of this research to find out antibacterial activity of ethanol extract leaves purple sweet potato against bacteria Salmonella sp. and Pseudomonas aeruginosa. This study used Broth microdilution with concentration of 2 mg/mL, 4μg/mL, 8 mg/mL, 16 mg/mL, 32 mg/mL, 64 mg/mL, 128 mg/mL, 256 mg/mL, 512 ug/mL,1024 mg/mL. Chloramphenicol used as a positive control at the same concentration, minimum inhibitory concentration (MIC) determination made by the 50 seen from the transmittance value the test bacteria and minimum bactericidal concentration (MBC) by the determination of the lowest concentration in which no visible bacterial growth. Based on the test microbroth dilution leaves purple sweet potatoes had antibacterial activity against Salmonella sp. and Pseudomonas aeruginosa with MIC 64 mg/mL in Salmonella sp. and 128 ug/mL Pseudomonas aeruginosa. KBM obtained 512 mg/mL in Salmonella sp. and 512 ug/mL Pseudomonas aeruginosa.
Vólvulos gástrico mesentérico axial recurrente, reporte de caso y revisión de la literatura
Authors: Roca Álvarez Dr. Camilo Andrés , Parra Córdoba Dr. José Fernando 
Published: December 2022

Se presenta caso clínico de paciente de 41 años, que presenta recurrencia de vólvulos gástrico, en quien se ha presentado con sintomatología inespecífica, siendo estos síndrome constitucional y episodios eméticos de más de un mes de evolución, en quien se llevó a realización de imágenes diagnosticas, identificando la patología mencionada, y en un primer tiempo fue llevada a reparación de herniación hiatal por laparoscopia y a la recurrencia, un año después fue llevada a gastrectomía subtotal con reconstrucción en Y de Roux. Dado presentación crónica, en paciente con factores de riesgo para volvulación gástrica debe hacerse hincapié en la educación del paciente para identificar signos de alarma que indiquen patología intraabdominal, para un manejo temprano.
Comportamiento del flujo sanguíneo cerebral en pacientes pediátricos quemados durante la fase ebb ingresados en una unidad de quemados
Authors: Silva Zarate Alicia Aída , Gil Vargas Manuel , Silva Campos Irlanda Mariel , Guevara Navarrete César Martín , López Santos Héctor Alfonso , Paredes Juárez Genaro Alberto , Benavides Suárez Sergio Adán , Martínez Tovilla Yaneth 
Published: December 2022

Introducción: la conservación del Flujo Sanguíneo Cerebral (FSC) es muy importante para preservar las funciones normales del encéfalo. La regulación de este, esta mediada principalmente por la capacidad contráctil de los vasos sanguíneos.
Objetivo: describir el comportamiento del flujo sanguíneo cerebral en la fase ebb de las quemaduras en pacientes pediátricos.
Material y métodos: se realizó un estudio prospectivo, descriptivo, prolectivo y transversal en pacientes pediátricos, con quemaduras en la fase ebb a los que se les incluyó en un protocolo ultrasonográfico de neuromonitorización.
Resultados: el grupo etario más afectado fue el de escolares (n=25) por género el masculino (n=37). La causa de quemaduras más común fue por escaldadura (n=42). Se encontró una asociación estadísticamente significativa entre el grupo etario y la causa de quemaduras (p<0.001). El índice de pulsatilidad fue mayor en el género masculino con 0.58 y en edad escolar con 0.61, el índice de resistencia fue igual entre géneros con 0.47 y mayor en adolescentes con 0.50, el índice de Lingegaard fue mayor en el género femenino con 1.31 y en edad escolar con 1.51.
Conclusiones: se encontró una correlación con tendencia positiva significativa entre el porcentaje de superficie corporal quemada y el índice de resistencia (p=0.031, rho=0.273).