bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intrinsic Capacity and Active and Healthy Aging Domains Supported by Personalized Digital Coaching: Survey Study Among Geriatricians in Europe and Japan on eHealth Opportunities for Older Adults
Authors: Stara Vera , Soraci Luca , Takano Eiko , Kondo Izumi , Möller Johanna , Maranesi Elvira , Luzi Riccardo , Riccardi Giovanni Renato , Browne Ryan , Dacunha Sébastien , Palmier Cecilia , Wieching Rainer , Ogawa Toshimi , Bevilacqua Roberta 
Published: July 2023

Background
The worldwide aging trend requires conceptually new prevention, care, and innovative living solutions to support human-based care using smart technology, and this concerns the whole world. Enabling access to active and healthy aging through personalized digital coaching services like physical activity coaching, cognitive training, emotional well-being, and social connection for older adults in real life could offer valuable advantages to both individuals and societies. A starting point might be the analysis of the perspectives of different professionals (eg, geriatricians) on such technologies. The perspectives of experts in the sector may allow the individualization of areas of improvement of clinical interventions, supporting the positive perspective pointed out by the intrinsic capacity framework.

Objective
The overall aim of this study was to explore the cross-national perspectives and experiences of different professionals in the field of intrinsic capacity, and how it can be supported by eHealth interventions. To our knowledge, this is the first study to explore geriatric care providers’ perspectives about technology-based interventions to support intrinsic capacity.

Methods
A survey involving 20 geriatricians or clinical experts in the fields of intrinsic capacity and active and healthy aging was conducted in Italy, France, Germany, and Japan between August and September 2021.

Results
The qualitative findings pointed out relevant domains for eHealth interventions and provided examples for successful practices that support subjective well-being under the intrinsic capacity framework (the benefits offered by personalized interventions, especially by promoting health literacy but avoiding intrusiveness). Moreover, eHealth interventions could be used as a bridge that facilitates and enables social engagement; an instrument that facilitates communication between doctors and patients; and a tool to enrich the monitoring actions of medical staff.

Conclusions
There is an unexplored and significant role for such geriatric perspectives to help the development process and evaluate the evidence-based results on the effectiveness of technologies for older people. This is possible only when clinicians collaborate with data scientists, engineers, and developers in order to match the complex daily needs of older adults.
Examining Predictors of Depression and Anxiety Symptom Change in Cognitive Behavioral Immersion: Observational Study
Authors: Ezawa Iony D , Hollon Steven D , Robinson Noah 
Published: July 2023

Background
Depressive and anxiety disorders are the most common mental disorders, and there is a critical need for effective, affordable, and accessible interventions. Cognitive Behavioral Immersion (CBI) is a novel group-based cognitive behavioral skills training program delivered by lay coaches in the metaverse that can be accessed through various modalities including virtual reality (VR) head-mounted displays or flat-screen devices. Combining its ability to offer empirically supported therapy skills in a digital setting that can still facilitate interpersonal variables (eg, working alliance and sense of social support) with the aid of lay coaches, CBI has the potential to help fill this critical need.

Objective
This study had 2 primary aims. First, we aimed to examine changes in depression and anxiety symptoms in a sample of individuals who participated in CBI. Second, we aimed to examine 2 interpersonal process variables (working alliance and web-based social support) as predictors of symptom changes. We predicted CBI participants would experience depression and anxiety symptom improvements and that such improvements would be associated with an increase in both interpersonal process variables.

Methods
The study sample consists of 127 participants who endorsed clinical levels of depression or anxiety symptoms during their first CBI session and attended at least 2 sessions. Participants were asked to complete self-report measures of depression symptoms, anxiety symptoms, alliance, and web-based social support throughout their participation in CBI.

Results
Repeated measures ANOVAs determined that depression and anxiety symptom scores differed significantly across sessions (Ps<.01). We also found participants’ web-based social support predicted improvement in depression symptoms (P=.01), but neither the alliance nor web-based social support predicted change in anxiety symptoms (Ps>.05). We also observed a significant difference in anxiety symptoms between participants who used a VR head-mounted display to access CBI and those who did not, such that participants who used VR head-mounted displays endorsed lower anxiety symptoms than those who did not at nearly every session (P=.04).

Conclusions
Participation in CBI is associated with both depression and anxiety symptom improvement. Web-based social support may play an important role in fostering changes in depression symptoms. Future studies are encouraged to continue examining the process of change in CBI with special attention paid to methods that can elucidate causal mechanisms of change.
Асоціації варіантів гена GHRL із розвитком ожиріння та метаболічних порушень у дітей
Authors: Abaturov A. , Nikulina A. 
Published: July 2023

Актуальність. Однонуклеотидні варіанти (single nucleotide variant — SNV) гена греліну (GHRL) супроводжуються продукцією дефектного протеїну препрогреліну, що може призводити до розвитку ожиріння та метаболічних порушень. Мета: вивчити асоціації гена SNV GHRL із розвитком різних фенотипів ожиріння в дітей. Матеріали та методи. Обстежено 252 пацієнтів з ожирінням віком 6–18 років. Основну групу (n = 152) становили діти з метаболічно нездоровим ожирінням (МНО). Контрольну групу (n = 100) представили діти з метаболічно здоровим ожирінням (MЗO). У 31 дитини основної та 21 дитини контрольної групи проведено повногеномне секвенування (CeGat, Німеччина). Рівень інтерлейкіну (IL) 1β у сироватці крові визначали методом імунохемілюмінесцентного аналізу, IL-6 — методом імуноферментного аналізу (Synevo, Україна). Результати. Асоціація з розвитком MНO була вищою для T-алеля SNV rs696217 гена GHRL у здорових осіб (t = 2,31; p < 0.05) та пацієнтів з ожирінням (t = 2,06; p < 0,05). Генотип GT SNV rs696217 був пов’язаний з інсулінорезистентністю (r = 0,40; p < 0,05) у групі MНO і зворотно корелював з умістом холестерину (r = –0,45) та холестерину ліпопротеїнів низької щільності (r = –0,39). Генотип TA SNV rs4684677 корелював із рівнем IL-6 (r = 0,74) у групі MЗO та з IL-1β (r = 0,35) у групі MНO, p < 0,05. Профілактика трансформації MЗO в MНO визначається T-алелем SNV rs34911341 (t = 2,29, p < 0,05). Висновки. Міссенс-варіанти rs696217, rs4684677 гена GHRL є SNV, високо асоційованими з ожирінням та розвитком метаболічних порушень.
Causes of proof construction failure in proof by contradiction
Authors: Hamdani Deni , Purwanto  , Sukoriyanto  , Anwar Lathiful 
Published: July 2023

Failure to deduce false suppositions in proof by contradiction is still considered “more difficult” than proving the conditional to in proof by contraposition. This study aims to identify the types of proof construction failures based on the action steps of proof by contradiction, then offer a framework of construction failure hypothesis specifically used in proof by contradiction. The research data were collected and analyzed from the work of students who have agreed to be research participants, a total of 83 students. The results of the analysis of student work successfully identified four types of failures, namely formulating suppositions, constructing and manipulating suppositions, identifying contradictions, and disproving suppositions. These four types of failures then became the material for the development of the hypothesis framework of a failure to construct proof by contradiction, which consists of 17 hypothesis nodes divided into three main hypotheses, namely: operational (action), affective (emotional), and foundational (logical reasoning). The failure hypothesis framework justifies that the sources of the failure of proof construction in proof by contradiction are understanding of the act of producing a proof by contradiction, emotionality towards the coherence of the construction steps, disproving suppositions, beliefs, use of appropriate definitions-theorems and axioms, and cognitive tension in proof by contradiction; and formal logic of the act of producing a proof by contradiction, as well as differences in the underlying logic with other acts.
Prospective elementary teachers’ informal mathematical proof using GeoGebra: The case of 3D shapes
Authors: Putra Zetra Hainul , Afrillia Yesi Martha , Dahnilsyah  , Tjoe Hartono 
Published: July 2023

Mathematical proofs play a paramount role in developing 21st-century skills, and the use of technology in mathematics learning has widely paved the way in the instruction of mathematical proofs. In mathematics education, GeoGebra has a significant role as a dynamic mathematics software in supporting students' learning process. This study aims to use GeoGebra in supporting prospective elementary teachers' mathematical proofs of the volume of 3-D shapes. This research used a case study method with 23 first-year prospective elementary teachers as participants from a public university in Riau, Indonesia. The data were gathered by means of students' work recordings in the GeoGebra classroom and video recordings from their interactions in the course of small group and classroom discussions. The videos were transcribed using verbatim, and then the mathematical proofs were analyzed using praxeological analysis. The findings show that prospective elementary teachers still had challenges to connect the construction of the volume of 3-D shapes using GeoGebra to its informal mathematical proofs. However, GeoGebra provides an opportunity to learn informal mathematical proofs for prospective elementary teachers.
OPTIMALISASI KELAS IBU HAMIL SEBAGAI UPAYA PENCEGAHAN STUNTING DI DESA TANJUNG LANJUT KABUPATEN MUARO JAMBI
Authors: Siregar Sri Astuti , Asparian Asparian , Syukri M. , Nurdini Lia 
Published: July 2023

Tindakan yang relatif ampuh dilakukan untuk mencegah stunting pada anak adalah selalu memenuhi gizi yang optimal sejak masa kehamilan. Salah satu upaya yang dapat dilakukan untuk meningkatkan pengetahuan bagi ibu hamil adalah melalui kelas ibu hamil. Kegiatan kelas ibu hamil bertujuan untuk meningkatkan pengetahuan, merubah sikap dan perilaku ibu agar memahami tentang pemeriksaan kehamilan, persalinan, nifas sampai kepada perawatan bayi baru lahir agar tumbuh kembang optimal. Tujuan pengabdian kepada masyarakat ini adalah untuk meningkatkan pengetahuan ibu hamil melalui kelas ibu hamil. Metode pengabdian dilakukan dengan pengukuran yang meliputi meliputi tinggi badan, kenaikan berat badan selama kehamilan dan pengukuran lingkar lengan atas (LILA) serta penyuluhan terkait stunting. Pengukuran pengetahuan dengan menggunakan kuesioner pre-post test. Hasil kegiatan didapatkan adanya peningkatan pengetahuan peserta sebesar 11,64 dimana sebelum dilakukan penyuluhan yaitu 6,71. Oleh sebab itu, diperlukan adanya perhatian yang lebih intensif serta motivasi yang diberikan kepada ibu hamil agar lenih rutin menghadiri kelas ibu hamil.
<strong>The DERMIS Study: Evaluation of Insulin Pump Infusion Sites in Type 1 Diabetes</strong> <strong>DERMIS: Evaluation of Pump Infusion Sites</strong>
Authors: Kalus Andrea , M Shinohara Michi , Wang Ruikang , D Baran Jesica , Dong Xiaofu , Khakpour Dori , Lu Jie , B. Hirsch Irl 
Published: July 2023

<p> </p>
<p><strong>Abstract</strong></p>
<p><em>Objective</em><strong>: </strong>Continuous subcutaneous insulin infusion (CSII) for type 1 diabetes is increasing in use. Pump site failures are common, yet little is known about the skin changes from pump use. Using noninvasive optical coherence tomography (OCT), OCT angiography (OCTA), and skin biopsies, we evaluated the skin changes of chronic insulin infusion.</p>
<p><em>Research Design and </em>Methods: In this cross-sectional study an OCT operating at 1310nm central wavelength with a bandwidth of 100 nm was performed immediately before skin punch biopsies were collected at three sites: a “current site”, infusion set removed at time of OCT and biopsy; a “recovery site”, infusion set removed 3 days prior to biopsy: and a “control” site, never used for any insulin infusion or injection.</p>
<p><em>Results</em><strong>: </strong>OCT and OCTA identified characteristics of increased inflammation and vessel density at pump sites compared to control sites. Histological analysis of pump sites showed differences in skin architecture including fibrosis, inflammation including increased tissue eosinophils and fat necrosis. Immunohistochemical staining showed differences between infusion sites and the control sites for staining of insulin-like-growth factor-1 and transforming growth factor β-3.</p>
<p><em>Conclusions</em>: These findings support allergic sensitization as a potentially common reaction at CSII sites. The leading candidates include insulin preservatives, plastic materials, or adhesive glue used in device manufacturing. The inflammatory response caused by these common allergic responses may result in tissue changes responsible for the infusion site failures seen frequently in clinical practice.</p>
Implementasi Metode Resitasi dan Diskusi untuk Meningkatkan Kemampuan Guru Menyusun RPP
Authors: Sriastiti I. A. Wayan Mayun 
Published: July 2023

Masih jarangnya dijumpai guru yang mau menyusun RPP sendiri untuk dilaksanakan pada kegiatan pembelajaran, serta menganggap RPP hanya sebagai pekengakp admistrasi saja, berpengaruh terhadap kemampuan guru dalam menysun RPP. Penelitian ini bertujuan untuk meningkatkan kemampuan menyusun perencanaan pembelajaran pada guru melalui menerapkan metode resitasi dan diskusi. Penelitian ini dilaksanakan sebanyak 2 siklus. Rancangan masing-masing siklus terdiri dari perencanaan, pelaksanaan, observasi/evaluasi dan refleksi. Subjek penelitian yang digunakan adalah guru-guru yang jumlahnya 7 orang yang terdiri dari 3 orang guru laki-laki dan 4 orang guru perempuan. Data dianalisis menggunakan statistik deskriptif. Berdasarkan data yang diperoleh dapat disimpulkan bahwa implementasi metode resitasi dan diskusi dapat meningkatkan kemampuan menyusun RPP pada guru. Hal ini terlihat berdasarkan adanya peningkatan kemampuan guru dalam menyusun RPP dengan nilai rata-rata dari prasiklus sebesar 70,48 meningkat pada siklus I menjadi 73,97 dan pada siklus II menjadi 77,78. Persentase kemampuan guru dalam menyusun RPP pada prasiklus sebesar 70,48% yang berada pada ketogori cukup, siklus I sebesar 73,97% yang berada pada kategori cukup, dan pada siklus II sebesar 77,78% yang berada pada kategori baik.
Modeling and Analysis of Quasi-2D Turbulence Dynamics in Shallow Waters
Authors: Protsenko S. V. , Protsenko E. A. 
Published: July 2023

Introduction. The work is devoted to the study of the generation and development of turbulent structures in shallow-water flows. For optimal water resource management, it is necessary to know what the consequences will be if the flow system changes as a result of human intervention. Basically, all fluid flows that relate to the practice of civil engineering are turbulent in nature. These are, for example, river and channel flows, tidal currents in the oceans and coastal seas. Shallow currents in the environment often include a wide range of vortex scales, ranging from micro-scale vortices to large-scale coherent structures with horizontal length scales that far exceed the depth of water (L >> H). The existence of such large structures is a typical characteristic of turbulence in shallow flow. This indicates the need for a systematic analysis of the problem, as well as modeling of such complex formalized systems. The purpose of this work is to model and analyze the dynamics of quasi-2D turbulence structures.Materials and Methods. Large-scale quasi-2D coherent structures (2 DCS) are investigated depending on the source and localization in the liquid column. Turbulent flows in the channel satisfying incompressible Navier-Stokes equations are considered. The numerical experiment was carried out on the basis of the “large eddy simulation” (LES) approach.The Results of the Study. Scenario of the dynamics of quasi-2D turbulence structures of the coastal zone is constructed, the formation of vortex structures is predicted.Discussion and Conclusions. The development of two-dimensional turbulence in shallow flows illustrates the processes that control quasi-two-dimensional turbulence, including the merging of individual vortices. The main mechanism controlling the decay of 2DCS is the loss of energy due to friction on the bottom, while the larger the size of the vortex relative to the depth, the faster the direct dissipation of its kinetic energy occurs.
STRATEGIC BASES OF FORMING THE CALENDAR OF CITY EVENTS COMPARATIVE ANALYSIS OF THE CITIES OF THE REGION IN THE PRE-PANDEMIC PERIOD
Authors: Vardevanyan Vardan 
Published: July 2023

The author of the article explores the peculiarities of the formation of the calendar of city events. Cities of Ukraine have already embarked on a path of fierce competition for tourist attractiveness. The fame and attractiveness of the city allows him not only to benefit from the costs incurred by tourists in the city. Such cities are faster to upgrade the infrastructure of the local market and rejuvenate the average age of the average citizen. Tourist attractiveness is the fulfillment of a tourist's expectations to receive a certain service / product of proper quality at a certain time. The city must continuously provide tourists with a wide range of such services. The only effective tool that allows you to perform this task is a properly formed calendar of city events.
The study examined the basic parameters of forming an effective calendar of events in the city. It is emphasized that any event takes place in a certain environment. It was determined that the main markers of such an environment are the potential of the city, the availability of suitable tourism infrastructure, the willingness of local elites and residents to invest in the development of tourist infrastructure, the availability of quality and development of new routes to other cities. Understanding that the features of the event environment, allows you to determine the criteria for selecting events and the principles of their placement in the calendar of events.
On the example of the calendar of events in Chernivtsi, Lviv and Kamyanets-Podilsky, the principles of composing the list of planned events were formulated.
We came to the conclusion that for cities that suffer from the actions of competitors, you need to review their strategies for forming a calendar of events, invent and quickly apply countermeasures. In addition, the pace of development of the tourism market in the pre-pandemic period was quite stable, in particular, the number of tourists increased, including and to Ukraine. In the post-pandemic period, tourist routes will be restored. The arsenal of advertising tools and techniques that cities will use to promote their events will be enriched with new tools. The competition will only intensify. Thus, for Ukrainian cities the issues of formation of tourist attractiveness become especially important. Therefore, to ensure the growth of tourist attractiveness, cities should properly use including such a tool as a calendar of city events.
RENT AS A PROSPECTIVE SEGMENT OF THE RESIDENTIAL REAL ESTATE MARKET: EXPERIENCE OF FOREIGN COUNTRIES
Authors: Tafiy Natalia , Bastrakov Daniil 
Published: July 2023

The article considers the problems of formation and development of the rented housing segment in foreign countries. The impact of changing consumers generations on the residential real estate market, which have other formats of consumer behavior, a different lifestyle, an approach to planning the structure and directions of consumer spending, other plans for the future. It is noted that in almost all countries there are laws that protect the rights of tenants, and an effective judicial system guarantees the protection of landlords' rights.
The experience of foreign countries and their regions in the regulation of the rental housing segment is analyzed: USA, Canada, Germany, France, Spain, Great Britain, Japan. Based on the analysis of international experience, it is concluded that in most countries the law regulates the organizational and legal aspects of rental relations, the legislative level also sets minimum standards and quality characteristics of rental housing, which are often the responsibility of regional authorities. state, province or land.
It is emphasized that there is an objective need to regulate the residential real estate market development, including in the rental segment, at the national, regional and local levels. It is noted that local governments of Ukraine should pay attention to this segment in the direction of developing "Regional standards of long-term lease", which will regulate relations, share responsibilities, responsibilities and rights, reconcile the interests of the tenant and the landlord.
MARKETING IS THE ESSENCE OF INTERACTION POINTS IN THE REGIONAL EDUCATIONAL NETWORK
Authors: Romaniuk Nadiia 
Published: July 2023

The article contains a procedure for conducting an empirical analysis of the regional educational network, which made it possible to process, systematize and streamline a significant array of empirical economic information about its nodes: "Education", "Science and Innovation", "Power", "Business", "Stakeholders".
An analysis of the nodes of the current regional educational network of the Chernivtsi region showed a sufficiently high potential of educational, business, innovative, methodological, event-driven, stakeholder subsystems, which allows it to take leading positions in many respects.
Many serious problems have been diagnosed, including educational migration, demographic situation, low innovation activity, leading to increased competition between business and education, between different levels of education, between regions and countries and require the transformation of the regional educational network with a focus on the needs of the territorial community, regional economy , society, on the creation of new types of educational institutions, the development of educational programs of a new generation, the development of alternative forms and formats of education, and most importantly - on the implementation of the concept of lifelong learning.