bluuebunny/crossref_metadata_2025_split huggingface dataset:
Necropsy findings and causes of loss in semi-domesticated reindeer (Rangifer tarandus tarandus) in Northern Norway
Authors: Mørk Torill , Eira Henrik Isaksen , Rødven Rolf , Nymo Ingebjørg H. , Blomstrand Berit Marie , Guttormsen Sandra , Olsen Line , Davidson Rebecca K. 
Published: August 2023

Abstract
Background: Reindeer herding in Norway is based on traditional Sámi pastoralism with the animals free ranging throughout the year. The animals move over large areas in varying terrain and often in challenging weather conditions. Winter crises, such as difficult grazing conditions caused by icing or large amount of snow, are survival bottlenecks for reindeer. Calves are especially vulnerable, and many may die from starvation during winter crises. Predation and starvation are the predominant narrative to explain losses, however, carcasses are difficult to find and often little remains after scavenging and decay. Documentation of the causes of death is therefore scarce.
Results: In this study, we investigated the cause of reindeer mortality in Troms and Finnmark, Nordland and Trøndelag during 2017-2019. Necropsies (n=125) and organ investigation (n=13) were performed to document cause of death. Body condition was evaluated using visual fat score and bone marrow fat index. A wide range of causes of death was detected. The diagnosis were categorized into the following main diagnostic categories: predation (n=40), emaciation (n=35), infectious disease (n=20), trauma (n=11), feeding related disease (n=5), neoplasia (4), others (n=6) and unknown (n=17). Co-morbidities were seen in a number of diagnoses (n=16).
Reindeer herders are entitled to economic compensation for reindeer killed by endangered predators, but a lack of documentation leads to a gap between the amount of compensation requested and what is awarded. An important finding of our study was that predators killed animals in good as well as poor condition during winter. Emaciation was shown to also be associated with infectious diseases, and not only attributable to winter grazing conditions.
Conclusions: This study highlights the importance of examining dead reindeer to gain knowledge about why they die on winter pasture. The work presented herein also shows the feasibility and value of increased documentation of reindeer losses during winter.
Influence of process parameters on the mechanical properties and corrosion resistance of dissimilar friction stir welded joints of AA2024-O and AA6061-O aluminum alloys
Authors: Soto-Diaz Roosvel , Sandoval-Amador Anderson , Escorcia-Gutierrez José , Unfried-Silgado Jimy 
Published: August 2023

Abstract
xIn this study, the influence of the process parameters, traverse and rotational speeds, of dissimilar friction stir welded joints of AA2024-O and AA6061-O aluminum alloys on the corrosion resistance was evaluated. Potentiodynamic tests using a 3.5% NaCl solution obtained open circuit potential curves and polarization curves showing the corrosion behavior for the different welding parameters. These data were correlated with those obtained by mechanical tests (microhardness, tensile, and fracture analysis) and microstructure analysis by optical microscopy and scanning electron microscopy. It was observed that the combined effect of the parameters influenced the variation of corrosion resistance. This was mainly evidenced by the improvement in corrosion resistance at 1200rpm − 65mm · min−1 which was related to the recrystallization of the grain size and the heat input presented. Corrosive attacks on the welded joints showed greater affectations in the presence of base material 1 (AA6061-O) with greater metallic dissolution. The attacks mentioned above were presented in different forms, such as pitting, localized, and selective, and were observed by scanning electron microscopy. Finally, in corrosive and mechanical terms, the best performing condition was 1200rpm − 65mm · min−1 compared to the low parameter 840rpm − 45mm · min−1 .
Quantum Confinement Detection using a Coupled Schrödinger System
Authors: Li Chun 
Published: August 2023

Abstract
Machine learning techniques have provided valuable insights into understanding the fundamental principles of physics. Recent studies have demonstrated the ability of deep neural networks (DNNs) to learn a wide range of differential equations (DEs) and classical Hamiltonian mechanics systems. This has led to the emergence of solving the inverse problem associated with partial differential equations using DNNs. In this paper, we propose a novel method for detecting quantum confinement by numerically solving the Schr¨odinger system on manifolds with nonlinear coupling. Our method exhibits remarkable performance in identifying various quantum phenomena. Moreover, our research introduces a promising approach for principled modeling and prediction in quantum processes. By combining deep learning with traditional models, our hybrid model leverages the strengths of both approaches, enhancing computational efficiency and enabling meaningful predictions for complex quantum physical processes. The integration of multiple deep learning principles with quantum physics enables effective handling of large datasets and addresses inverse challenges related to intricate dynamical systems and physical phenomena.
Comparative analysis on root exudate and rhizosphere soil bacterial assembly between tomatoes and peppers infected by Ralstonia
Authors: Yan Mengyuan , Wu Meng , Liu Ming , Li Guilong , Bao Ying , Liu Kai , Li Zhongpei 
Published: August 2023

Abstract
Background and Aims
The rhizosphere environment regulated by root secretory activity and rhizosphere microbial interactions plays an essential role in resisting soil-borne diseases, while the host species is an important factor that affects the composition of root exudates and rhizosphere microbiomes. However, few studies have been done on the characteristics of root exudates and bacterial communities in terms of composition, diversity, and functional potential when host plants of different species are subjected to the same disease.
Methods
In this study, we examined the rhizosphere soil bacteria and root exudates of both healthy and diseased tomatoes and peppers employing metabolomics and amplicon techniques.
Results
Our findings indicated that variations existed in both root exudates and the bacterial community among different host species and health states. The diversities of both rhizosphere metabolites and bacterial communities were significantly reduced in different diseased plants. Although pepper and tomato resisted the invasion of Ralstonia by recruiting different potentially beneficial bacteria, their rhizosphere bacterial communities had the same functional potential. In contrast with diseased rhizosphere soil, healthy rhizosphere soil had many more functional pathways associated with disease suppression and plant growth.
Conclusions
This study highlighted the crucial role of host plants in shaping the rhizosphere environment and revealed the variation characteristics of root exudes and rhizosphere bacteria of different host plants induced by the same disease.
Successful rehabilitation after multiple severe complications following orthognathic surgery: A case report
Authors: Holm Cecilia Koskinen , Johansson Lena C , Brundin Malin , Sjöström Mats 
Published: August 2023

Abstract
Complications of orthognathic surgery are quite rare, but they cause suffering in affected individuals. The range of complications is broad and includes both hard and soft tissue. We here present a case of a fully healthy woman who underwent bimaxillary orthognathic surgery and experienced multiple complications both peri- and post-operatively. We also present the result after restorative surgery and endodontic and prosthodontic treatment resulting in a successful rehabilitation.
Efficacy of N-acetylcysteine plus pirfenidone in the treatment of idiopathic pulmonary fibrosis：a systematic review and meta-analysis
Authors: Zhang Xiu-Li , Cao Ying , Zheng Bo 
Published: August 2023

Abstract
Background
Numerous studies have demonstrated the potential of pirfenidone to enhance the prognosis of patients afflicted with idiopathic pulmonary fibrosis (IPF). Although N-acetylcysteine (NAC) is utilized as an antioxidant in IPF treatment, the combination of NAC and pirfenidone has produced inconsistent outcomes in certain studies. To assess the clinical effectiveness and safety of NAC plus pirfenidone (designated as the treatment group) versus pirfenidone monotherapy (designated as the control group), we conducted a systematic review and meta-analysis of randomized controlled trials (RCTs).
Methods
RCTs of NAC plus pirfenidone were reviewed searching from databases and networks of unpublished and published studies in any language. Using pair-wise meta-analysis, changes in pulmonary function test (PFT) parameters and safety were evaluated .
Results
Two independent reviewers selected and obtained data from 5 RCTs (n = 398), comprising 1 study from Japan, 1 from Europe, and 3 from China. Based on changes in forced vital capacity (ΔFVC), changes in forced vital capacity percent predicted (ΔFVC%), changes in 6-minute walking test distance (Δ6MWT), and changes in percentage of predicted carbon monoxide diffusing capacity (ΔDLco%), the two groups were found to be comparable in terms of clinical efficacy. Both groups demonstrated similar and favorable safety profiles with respect to at least one side effect, severe side effects, gastrointestinal effects, and skin effects and mortality rates.
Conclusion
Based on this systematic review and meta-analysis, NAC plus pirfenidone did not
Investigating the effect of positive counseling on the anxiety of pregnant mothers over 35 years old
Authors: Jalilvand Hadis , EmamgholiKhooshehchin Taraneh 
Published: August 2023

Abstract
Background and objectives:
Pregnancy is a pleasant time for most women, but sometimes pregnant mothers have worries. Counseling during pregnancy can play an important role in reducing the anxiety of pregnant mothers. The present study was conducted with the aim of investigating the effect of positive counseling on the anxiety of pregnant mothers over 35 years old.
Materials and methods:
This study was conducted on pregnant mothers over 35 years old in Zanjan. the study was approved by the Human Experimentation Ethics Committee of Zanjan University of Medical Sciences (IR.ZUMS.REC.1400.110) and was registered in the Iranian Registry of Clinical Trials under the registry number IRCT20160521027994N7 in 18/07 /2021. The tools of this study are demographic form, Vandenberg Pregnancy Anxiety Questionnaire and Dass-21. After completing the questionnaire, the eligible people were randomly divided into 2 intervention and control groups. The intervention group received positive counseling during eight virtual sessions of 70-90 minutes, and the control group received only routine care, and at the end, the questionnaires were completed again. Then the data were analyzed with Klomogrof-Smirnov statistical test, independent t, paired t with SPSS software.
Results:
The mean variable of Vandenberg pregnancy anxiety before the intervention in the intervention group is 63.608±18.717 and in the control group is 55.652±17.933, which does not have a statistically significant difference (P=0.148).
After the intervention, this average is 38.608 ± 13.275 in the intervention group and 60.521 ± 17.526 in the control group, which has a statistically significant difference (P=0.000).
Conclusion:
positive counseling reduces the anxiety of pregnant mothers over 35 years old.
ChaC1-based drug screenings identify a synergistic lethal effect of auranofin and proteasome inhibitors in hepatocellular carcinoma cells.
Authors: Zheng Min , Yu Cheng , Liu Jinyu , Jian Hejia , Jiang Mingting , Zhang Binghui , Lin Meiyan , Lin Junjin , Zhong Chuan-Qi 
Published: August 2023

Abstract
The gamma-glutamylcyclotransferase, ChaC1, is an enzyme catalyzing glutathione (GSH) degradation. In this study, we performed ChaC1 activity-based drug screening from FDA-approved drug library to identify GSH-detoxifying drugs, and found that ChaC1 overexpression mediated glutathione depletion largely enhanced the anticancer efficacy of auranofin (AUR) in hepatocellular carcinoma (HCC) cells. AUR treatment in ChaC1 overexpressed cells led to constitutive activation of oxidative stress and induction of endoplasmic reticulum (ER) stress response genes, such as ATF4 and ATF3. Proteomic study showed that co-treatment of AUR and ChaC1 overexpression upregulated a series of cell death promoting genes, such as DEDD2 and DDIT4. To mimic ChaC1 overexpression by inducing endogenous ChaC1 high expression, we performed ChaC1 expression-based drug screening for ChaC1 inducing drugs from the same drug library, and found that proteasome inhibitors (PIs), including Bortezomib (BTZ), Ixazomib (IXZ) and Delanzomib (DLZ), dramatically induced endogenous ChaC1 expression in an ATF4 dependent manner in HCC cells. Furthermore, combinational treatment of AUR and PIs synergistically led to cell death, which could be inhibited by N-Acetyl-L-cysteine (NAC) and cycloheximide (CHX), but not Z-VAD-FMK (zVAD), necrostatin-1 (Nec-1), ferrostatin-1 (Fer-1) or chloroquine (CQ). Induction of DEDD2 and DDIT4 was also observed in PIs and AUR co-treated cells. Finally, blockade of the ATF4-ChaC1 pathway suppressed cell death and upregulation of DEDD2 and DITT4 in response to PIs and AUR co-treatment in HCC cells. Together, our study identified a synergistic lethal effect of PIs and AUR in HCC cells through ChaC1-based drug screenings, suggesting that combination of PIs and AUR might be repurposed for HCC treatment.
Exploring the nutraceutical potential and safety assessment of wild edible plants in Sikkim, India: A comprehensive analysis
Authors: Seal Tapan , Chaudhuri Kausik , Pillai Basundhara , Sherpa Norbu , Gogoi Rajib 
Published: August 2023

Abstract
The consumption of wild edible plants has been instrumental in addressing food and nutritional needs and improving the health of marginalized communities in rural areas worldwide. This study aimed to assess the nutritive value, mineral content, vitamin content, and toxicological status of ten wild edible plants, namely Aralia armata, Macropanax dispermus, Fagopyrum dibotrys, Heracleum wallichii, Tupistra clarkei, and Rumex nepalensis. These plants are commonly consumed by tribal communities in Sikkim, India. Samples of these plants were collected from various regions in Sikkim, and their nutraceutical potential was evaluated using established food analysis methods recommended by the Association of Official Analytical Chemists. The analysis revealed high protein contents in several species, notably in A. armata (19.30±1.01%). Carbohydrate content ranged from 6.42±0.10% (R. nepalensis) to 11.16±0.48% (T. clarkei). Moreover, all plants exhibited significant mineral content, including sodium, potassium, calcium, iron, zinc, and magnesium. Additionally, water-soluble vitamins such as vitamin C (11.51±0.24 - 87.56±0.41 mg/100g of dry plant material) as well as B1, B2, B3, B5, B6, and B9 were present in appreciable amounts. The levels of antinutrients, such as oxalate, phytate, and saponin, as well as heavy metals (lead, chromium, cadmium, and mercury), were found to be below the established toxic thresholds in all plants. Thus, they pose no immediate health risks associated with these compounds. Furthermore, assessments of haemolytic toxicity, cytotoxicity, and genotoxicity of water extracts from the wild edible plants indicated their safety for human consumption. Therefore, this study highlights the potential utilization of wild edible plants as a source of dietary supplements, potentially leading to their commercialization. Understanding consumer perceptions towards wild edible plants in India is crucial in this regard.
Effects of Transabdominal Preperitoneal (TAPP) repair combined with biological mesh on reproductive function in male inguinal hernia patients of reproductive age: A single-center retrospective study
Authors: Zhang Li-Xiao , Kang Jia-Qi , Zhang Li-Fei , Ye Zhi-Bin , Zhao Hong-Yu , Liang Wei 
Published: August 2023

Abstract
Objective
To investigate the impact of Transabdominal Preperitoneal (TAPP) repair combined with biological mesh on the reproductive function of male inguinal hernia patients during their reproductive period, we conducted a retrospective analysis.
Methods
Sixty male inguinal hernia patients admitted to our department from October 2015 to October 2021 were included in the study. All patients underwent TAPP combined with biological mesh performed by the same surgical team. Prior to surgery, as well as at 3, 6, and 12 months post-surgery, bilateral testicular volume, testicular temperature, testicular blood perfusion, peripheral serum testosterone concentration, and semen analysis were assessed.
Results
The preoperative testicular volume, temperature, and blood perfusion were compared between the healthy side and the affected side. Additionally, the testicular volume, temperature, blood perfusion of the affected side, peripheral blood testosterone concentration, and semen analysis were compared at four different time points: before operation, 3 months after operation, 6 months after operation, and 12 months after operation. It is worth noting that all P values were found to be greater than 0.05.
Conclusions
Transabdominal Preperitoneal repair combined with biological mesh has no significant effect on the reproductive function of reproductive male patients with inguinal hernia.
The comparison of sereve OSAHS and mild-moderate OSAHS and analysis of risk factors
Authors: Lv Meng , Xu Xueyun , He Yanyu , Jiang Yuting , Geng Yaxuan , Wang Zhihui , Zhang Zhen , Wang Fengqian , Wang Shuqi , Wang Yuqing 
Published: August 2023

Abstract
Obstructive sleep apnoea hypopnea syndrome（OSAHS） can result in neurobehavioral and cardiovascular complications and growth impairment ,especially sereve OSAHS，We explored risk factors for severe OSAHS in children who snored and who visited the Children's Hospital of Soochow University from June 2017 to October 2021.A total of 142 patients were enrolled, including 104 patients in the mild-moderate OSAHS group and 38 patients in the severe OSAHS group. Our study found that age、tonsillar hypertrophy were risk factors for severe OSAHS, indicating that this factor has certain clinical significance for the identification of patients with severe OSAHS.
Outage Performance and Energy Efficiency Optimization of Wireless-Powered Millimeter-Wave Sensor Networks
Authors: Fuan Xiao , Xiaowu Li , Kun Tang , Entao Luo 
Published: August 2023

Abstract
With the widespread use of wireless sensor networks, one of the most pressing concerns is extending the lifetime of the sensors. By deploying directional antenna arrays, millimeter wave (mmWave) is a possible candidate for wireless energy transfer (WET). This paper investigates a beneficial combination of WPT and data transmission in a typical mmWave sensor network with Rayleigh channels, where a transmission interval can be divided into two sub-intervals. During the first sub-interval, one hybrid access point (HAP) employs beamforming techniques to transfer energy for serving multiple sensors within the service sector. The sensors then transmit their individual signal in turn to the HAP based on time division multiple address (TDMA) strategy by using the whole harvested energy. According to stochastic geometry, the exact and approximate expressions of conditional beam outage probability for the considered system are determined, respectively. The optimal time allocation of energy harvesting and data transmission for sensors is examined in order to maximize the energy efficiency of the system. The optimization problem can be translated into corresponding parametric form, and the resulting optimization problem can be solved using the Lagrange dual method with Karush-Kuhn-Tucker (KKT) conditions. The numerical results show the variation trend of the beam outage probability under various parameters and verify the accuracy of the theoretical analyses. Furthermore, the simulation results illustrate that the proposed optimal time allocation strategy can significantly enhance the overall energy efficiency of the system compared with other similar scheme.
The effects of living arrangements on dietary diversity and depression among Chinese older adults
Authors: Xian Xiaobing , Yu Rong , Qu Linhan , Ye Mengliang 
Published: August 2023

Abstract
Background
There is growing evidence that addressing the health problems associated with population aging is imminent. We aimed to explore the effects of living arrangements on dietary diversity and mental health from an older Chinese population and to examine the mediating role of dietary diversity to provide a theoretical basis for how to better promote healthy aging.
Methods
Using data from the seventh Chinese Longitudinal Healthy Longevity Survey (CLHLS) and including relevant basic demographic characteristics variables as control variables, this study used logistic regression to investigate the relationship between living arrangements of older adults on dietary diversity, depression and anxiety, and used the PROCESS procedure to test for mediating effects.
Results
Older adults living with their families and those living in nursing homes had higher dietary diversity scores compared to those living alone. Older adults living in nursing homes were more likely to acquire depression than those living alone, and those living with family members were at lower risk of depression. There was no significant effect of living arrangement of older adults on anxiety. The mediating effect of dietary diversity between living arrangement and depression was significant.
Conclusion
Living arrangements directly affect older people's dietary diversity and depression, and dietary diversity mediates the relationship between living arrangements and depression. Our findings can contribute to current theory and knowledge and provide insights into social policy, elderly services, and social work interventions for the older adults in China.