bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sorption properties of paper treated with silane-modified starch
Authors: Majka Jerzy , Perdoch Waldemar , Czajkowski Łukasz , Mazela Bartłomiej , Olek Wiesław 
Published: August 2023

AbstractSorption properties of paper products are important when applying paper as the packaging material. Hydrophobicity, i.e. reduced affinity of paper surface to liquid water, is of particular importance from the point of view of the direct impact on packed goods. However, hygroscopicity of the material is significant during storage of goods. The analysis of changes in the hygroscopic properties of paper products induced by the treatment with silane modified starch was presented. The results on the hygroscopicity of treated paper were related to the previously published results on the hydrophobicity. The discrete values of equilibrium moisture content allowed constructing adsorption and desorption isotherms. The three-parameter Guggenheim, Anderson, and De Boer (GAB) model, the four-parameter Generalized D’Arcy and Watt (GDW), and Yanniotis and Blahovec (Y-B) sorption isotherm models were used to quantify the hygroscopic properties for all options of untreated and modified paper samples. The effectiveness of silanes for improving hygroscopic properties was determined and compared to their impact on hydrophobicity of the studied materials. It was found that 1H, 1H, 2H, 2H-perfluorooctyltriethoxysilane was the only silane improving hydrophobic and hygroscopic properties. The analysis of the applied models of sorption isotherms depicted that the GAB model was not valid for describing water sorption isotherms in the case of the tested materials, while the GDW and Y-B models provided a much more realistic description of water sorption mechanisms. The evaluation of the results of fitting the GDW model indicated that water molecules bonding to the primary sites was the dominating mechanism of sorption.
Variable exponent diffusion for image detexturing
Authors: Fayolle Pierre-Alain , Belyaev Alexander G. 
Published: August 2023

AbstractWe consider a variational approach to the problem of structure + texture decomposition (also known as cartoon + texture decomposition). As usual for many variational problems in image analysis and processing, the energy we minimize consists of two terms: a data-fitting term and a regularization term. The main feature of our approach consists of choosing parameters in the regularization term adaptively. Namely, the regularization term is given by a weighted$$p(\cdot )$$p(·)-Dirichlet-based energy$$\int \!a({\varvec{x}}){\,\!|\,\!}\nabla u {\,\!|\,\!}^{p({\varvec{x}})}$$∫a(x)|∇u|p(x), where the weight and exponent functions are determined from an analysis of the spectral content of the image curvature. Our numerical experiments, both qualitative and quantitative, suggest that the proposed approach delivers better results than state-of-the-art methods for extracting the structure from textured and mosaic images, as well as competitive results on image enhancement problems.
Image‐free handheld robotic‐assisted technology improved the accuracy of implant positioning compared to conventional instrumentation in patients undergoing simultaneous bilateral total knee arthroplasty, without additional benefits in improvement of clinical outcomes
Authors: Albelooshi Ali , Hamie Muhieddine , Bollars Peter , Althani Saeed , Salameh Rami , Almasri Malak , Schotanus Martijn G. M. , Meshram Prashant 
Published: August 2023

AbstractPurposeThe purpose of this study was to compare the clinical and radiological outcomes in patients who underwent simultaneous bilateral total knee arthroplasty (SB‐TKA) using either robotic‐assisted TKA (RA‐TKA) or conventional TKA (C‐TKA).MethodsIncluded were the patients who underwent SB‐TKA between January 2018 and January 2020 and had a minimum follow‐up of 2 years. Of 151 patients included, 117 patients were operated using an image‐free handheld robotic sculpting system (RA‐TKA group) and 34 patients operated using conventional instrumentation (C‐TKA group). The key outcomes noted were multiple patient‐reported outcomes (PROs), adverse events, and radiological outcomes. Two investigators independently measured the radiological outcomes on pre‐ and post‐operative radiographs in coronal plane (medial proximal tibial angle [MPTA] and anatomic lateral distal femoral angle [aLDFA]) and sagittal plane (posterior tibial slope [PTS] and posterior condylar offset [PCO]). The chi‐square test was used to examine categorical variables. Student’s t test was used to analyze the continuous variables.ResultsPatients in both groups were similar in baseline characteristics (gender, body mass index, incidence of comorbidities, and length of hospital stay) except that RA‐TKA group patients younger (66.7 ± 8.9 vs 70.4 ± 10.5, P = 0.037) than C‐TKA group. The operative time was longer in RA‐TKA group as compared to C‐TKA (189.3 ± 37.1 vs 175.0 ± 28.2, P = 0.040). The final PROs at each were similar between the two groups (P > 0.05). The values of PROs at final follow‐up in RA‐TKA compared to C‐TKA were VAS pain (0.4 ± 0.9 vs 0.4 ± 0.5), KOOS‐JR (89.3 ± 5.8 vs 87.1 ± 5.3), and physical (55.9 ± 2.8 vs 55.4 ± 3.2), mental (61.1 ± 4.4 vs 60.2 ± 4.7) component of VR‐12 scores, and KSS satisfaction (37.5 ± 1.1 vs 37.1 ± 2.2) (all P > 0.50 or non‐significant [n.s.]). While one patient in RA‐TKA required revision of femoral component for peri‐prosthetic fracture, none of the patient in conventional group were revised (0.85% vs 0%, P = n.s.). The proportion of patients with outliers in RA‐TKA group was lower for aLDFA (2.6% vs 22.1%, P < 0.01) and PTS (0% vs 35%, P < 0.01).ConclusionThis comparative study in patients undergoing SB‐TKA found reduction of outliers in femoral and tibial implant positioning with RA‐TKA as compared to C‐TKA. There were no differences in both groups for pain, function, and satisfaction at a minimum of 2 years of follow‐up.Level of evidenceIII Therapeutic Study.
Joint line obliquity after lateral closing‐wedge high tibial osteotomy does not adversely affect clinical and radiological outcome: a 5‐year follow‐up study
Authors: Xie Tianshun , Huizinga Maarten R. , van den Akker‐Scheek Inge , van der Veen Hugo C. , Brouwer Reinoud W. 
Published: August 2023

AbstractPurposeTo analyze the association between change in knee joint line obliquity (KJLO) and patient‐reported outcome, radiological progression of osteoarthritis, and surgical survival after lateral closing‐wedge high tibial osteotomy (HTO).MethodsA cohort of 180 patients treated in one single hospital with lateral closing‐wedge HTO was examined. KJLO was defined by the medial proximal tibial angle (MPTA). To assess the association between KJLO and patient‐reported outcome, radiological progression of osteoarthritis, and surgical survival, patient groups were defined: I, postoperative MPTA < 95.0°; II, postoperative MPTA ≥ 95.0°; A, MPTA change < 8.0°; B, MPTA change ≥ 8.0°. Propensity score matching was used for between‐groups (I and II, A and B) covariates matching, including age, gender, preoperative lower limb alignment, preoperative medial joint space width (mJSW), preoperative Western Ontario and McMaster Universities osteoarthritis Index (WOMAC) score, wedge size, and postoperative follow‐up time. Patient‐reported outcome was assessed by the WOMAC questionnaire, radiological progression of osteoarthritis by mJSW and Kellgren–Lawrence (KL) grade progression (≥ 1) preoperatively and at follow‐ups (> 2 years). Failure was defined as revision HTO or conversion to knee arthroplasty.ResultsAfter propensity score matching, groups I and II contained 58 pairs of patients and groups A and B contained 50 pairs. There were no significant differences in postoperative WOMAC score or surgical failure rate between groups I and II or between groups A and B (p > 0.05). However, the postoperative mJSW was significantly lower in group I than group II (3.2 ± 1.6 mm vs 3.9 ± 1.8 mm; p = 0.018) and in group A than group B (3.0 ± 1.7 mm vs 3.7 ± 1.5 mm; p = 0.040). KL grade progression rate was significantly higher in group I than group II (53.4% vs 29.3%; p = 0.008) and in group A than group B (56.0% vs 28.0%; p = 0.005).ConclusionIncreased KJLO (postoperative MPTA ≥ 95.0°) or MPTA change ≥ 8.0° after lateral closing‐wedge HTO does not adversely affect patient‐reported outcome, radiological progression of osteoarthritis, or surgical survival at an average 5‐year follow‐up.Level of evidenceIII, retrospective cohort study.
A novel prognosis-prediction model based on coagulation indicators in secondary hemophagocytic lymphohistiocytosis
Authors: Wang Shixuan , Lv Kebing , Zhou Yulan , Cheng Xiaoye , Chen Zhiwei , Shen Huimin , Li Fei 
Published: August 2023

Abstract Secondary hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disease. In the present retrospective study, we aimed to investigate coagulation disorders and their outcome implications in patients with secondary HLH. We evaluated clinical characteristics and the relationship between coagulation indices and prognosis in HLH patients (n = 141). The information, including clinical symptoms, laboratory indicators, and coagulation indices, was evaluated. Coagulation disorders and bleeding events occurred in 95 (67.4%) and 60 (42.6%) patients, respectively. A coagulation index analysis primarily showed elevated levels of D-Dimer, the international standardized ratio (INR), prothrombin time (PT), activated partial thromboplastin time (APTT), and thrombin time (TT), while the prothrombin activity, fibrinogen levels, and platelet levels were significantly decreased. Dominant disseminated intravascular coagulation (DIC) occurred in 76 patients (53.9%). Patients with lymphoma-associated hemophagocytic syndrome (LAHS) frequently exhibited apparent coagulation disorders. Multivariate analysis revealed that age ≥ 29.5 years, bleeding events, APTT ≥ 47.3 s, fibrinogen ≤ 1.68 g/L, and absolute neutrophil counts (ANC) of ≤ 1.21 × 109/L were independent prognostic factors. We thereby devised a prognostic scoring system and stratified patients into low-risk (0–2 points), intermediate-risk (3–4 points), and high-risk (5–7 points) groups, and the 1-year overall survival rates in the above-mentioned groups were 66.40%, 40.00%, and 2.30%, respectively (P < 0.0001). In conclusion, coagulation dysfunctions and bleeding tendencies were common characteristics in HLH patients. We constructed a novel prognostic score model based on APTT, fibrinogen level, ANC, age, and bleeding events, which had superior prognostic value compared with these markers alone.
Occupational variation in incidence of oropharyngeal cancer in the Nordic countries
Authors: Nikkilä Rayan , Mäkitie Antti , Carpén Timo , Hansen Johnni , Heikkinen Sanna , Lynge Elsebeth , Selander Jenny , Mehlum Ingrid Sivesind , Torfadottir Jóhanna Eyrún , Salo Tuula , Pukkala Eero 
Published: August 2023

Abstract
Purpose
Evaluate the occupational variation in incidence of oropharyngeal cancer (OPC).

Methods
We calculated standardized incidence ratios (SIRs) of OPC in occupational categories in the Nordic countries relative to the entire national populations. The data covered 6155 OPC cases.

Results
Among men high risk of OPC was observed, among else, in waiters (SIR 6.28, 95% CI 4.68–8.26), beverage workers (SIR 3.00, 95% CI 1.72–4.88), and artistic workers (SIR 2.97, 95% CI 2.31–3.76). Among women high risk of OPC was observed in waiters (SIR 2.02, 95% CI 1.41–2.81) and packers (SIR 1.73, 95% CI 1.07–2.64). The lowest SIRs were observed in female gardeners (SIR 0.27, 95% CI 0.12–0.51) and male farmers (SIR 0.30, 95% CI 0.25–0.35).

Conclusion
The 20-fold variation in incidence of OPC between occupations needs further investigation in studies with detailed information on occupational and non-occupational risk factors.
Zirconium/hafnium fractionation and rare earth element systematics in sub-cratonic garnet pyroxenites, Norway
Authors: Spengler Dirk , Opitz Joachim 
Published: August 2023

AbstractTen previously studied garnet pyroxenites and one eclogite from orogenic peridotites in the Western Gneiss Region of Norway were analysed for whole-rock major and trace and mineral trace elements to characterise the evolutionary stages of the East Greenland sub-cratonic mantle. A continuous range of whole-rock MgO contents (17–30 wt.%) correlates inversely with $$\hbox {Na}_2\hbox {O}$$

Na
2

O

, $$\hbox {Al}_2\hbox {O}_3$$

Al
2

O
3

, and CaO contents. In contrast, rare earth element (REE) compositions allow the samples to be devided into two types. Type I samples have relatively flat primitive mantle (PM) normalised REE patterns (0.4$$-$$
-
6.8 times PM values) with minor fractionation of middle–heavy REEs. Type II samples are simlar to type I samples but have higher light REE contents (6.1–57 times PM values) that reflect metasomatic enrichment. Whole-rock Zr contents (1–$$27\,\upmu \hbox {g}\,\hbox {g}^{-1}$$

27

μ
g

g

-
1

) and Zr/Hf ratios (17–39) are positively correlated. Type I samples have low Zr/Hf ratios that mostly differ from type II samples, indicating that metasomatism modified the initially sub-chondritic Zr/Hf ratios. Garnet Zr–Zr/Hf–Y–Ti systematics suggest that metasomatic enrichment transformed the type I samples into type II samples, consistent with processes observed in other cratonic areas (e.g., the northern East European Platform and the Kaapvaal Craton). The formation of type I pyroxenite in dunite from a melt at $$\sim 100\,\text {km}$$

∼
100

km

depth implies the sub-chondritic Zr/Hf ratios were inherited from that melt. Such melts are thought to form by melting of garnet-bearing, melt-depleted mantle, which is consistent with models for recycling of Archaean palaeo-oceanic crust throughout the mantle prior to the formation of the sub-cratonic lithosphere beneath East Greenland.
Understanding the genetic mechanisms and cognitive impairments in Down syndrome: towards a holistic approach
Authors: Abukhaled Yara , Hatab Kenana , Awadhalla Mohammad , Hamdan Hamdan 
Published: August 2023

AbstractThe most common genetic cause of intellectual disability is Down syndrome (DS), trisomy 21. It commonly results from three copies of human chromosome 21 (HC21). There are no mutations or deletions involved in DS. Instead, the phenotype is caused by altered transcription of the genes on HC21. These transcriptional variations are responsible for a myriad of symptoms affecting every organ system. A very debilitating aspect of DS is intellectual disability (ID). Although tremendous advances have been made to try and understand the underlying mechanisms of ID, there is a lack of a unified, holistic view to defining the cause and managing the cognitive impairments. In this literature review, we discuss the mechanisms of neuronal over-inhibition, abnormal morphology, and other genetic factors in contributing to the development of ID in DS patients and to gain a holistic understanding of ID in DS patients. We also highlight potential therapeutic approaches to improve the quality of life of DS patients.
Ulinastatin ameliorated streptozotocin-induced diabetic nephropathy: Potential effects via modulating the components of gut-kidney axis and restoring mitochondrial homeostasis
Authors: Rizk Fatma H. , El Saadany Amira A. , Atef Marwa Mohamed , Abd-Ellatif Rania Nagi , El-Guindy Dina M. , Abdel Ghafar Muhammad T. , Shalaby Marwa M. , Hafez Yasser Mostafa , Mashal Shaimaa Samir Amin , Basha Eman H. , Faheem Heba , Barhoma Ramez Abd-Elmoneim 
Published: August 2023

AbstractGrowing evidence supports the role of the gut-kidney axis and persistent mitochondrial dysfunction in the pathogenesis of diabetic nephropathy (DN). Ulinastatin (UTI) has a potent anti-inflammatory effect, protecting the kidney and the gut barrier in sepsis, but its effect on DN has yet to be investigated. This study aimed to assess the potential mitigating effect of UTI on DN and investigate the possible involvement of gut-kidney axis and mitochondrial homeostasis in this effect. Forty male Wistar rats were divided equally into four groups: normal; UTI-treated control; untreated DN; and UTI-treated DN. At the end of the experiment, UTI ameliorated DN by modulating the gut-kidney axis as it improved serum and urinary creatinine, urine volume, creatinine clearance, blood urea nitrogen, urinary albumin, intestinal morphology including villus height, crypt depth, and number of goblet cells, with upregulating the expression of intestinal tight-junction protein claudin-1, and counteracting kidney changes as indicated by significantly decreasing glomerular tuft area and periglomerular and peritubular collagen deposition. In addition, it significantly reduced intestinal and renal nuclear factor kappa B (NF-κB), serum Complement 5a (C5a), renal monocyte chemoattractant protein-1 (MCP-1), renal intercellular adhesion molecule 1 (ICAM1), and renal signal transducer and activator of transcription 3 (STAT3), mitochondrial dynamin related protein 1 (Drp1), mitochondrial fission 1 protein (FIS1), mitochondrial reactive oxygen species (ROS), renal hydrogen peroxide (H2O2), and 8-hydroxy-2'-deoxyguanosine (8-OHdG) levels. Furthermore, it significantly increased serum short chain fatty acids (SCFAs), and mitochondrial ATP levels and mitochondrial transmembrane potential. Moreover, there were significant correlations between measured markers of gut components of the gut-kidney axis and renal function tests in UTI-treated DN group. In conclusion, UTI has a promising therapeutic effect on DN by modulating the gut-kidney axis and improving renal mitochondrial dynamics and redox equilibrium.
Cerebral microstructural changes in children suffering from hemolytic uremic syndrome
Authors: Bültmann Eva , Zapf Antonia , Mussgnug Hans Joachim , Kanzelmeyer Nele , Hartmann Hans 
Published: August 2023

AbstractTo evaluate microstructural cerebral changes in children suffering from typical hemolytic uremic syndrome (HUS) based on apparent diffusion coefficient (ADC) maps. For 12 pediatric HUS patients (0.8 - 14.6 years of age) conventional magnetic resonance imaging (cMRI) at 1.5 T was retrospectively analyzed. ADC values were measured in 35 different brain regions and compared with age-related, previously published ADC reference values from a healthy pediatric control group. The HUS cohort was divided into 2 subgroups depending on clinical outcome. Subgroup A showed poor neurological outcome whereas subgroup B demonstrated improvement without lasting neurological deficits. Qualitative analysis revealed lesions by diffusion-weighted imaging (DWI) with hypointense correlate on the ADC map in basal ganglia and/or thalami and corresponding T2 hyperintensities in the majority of patients in Subgroup A (80%). Those in Subgroup B did not show qualitative DWI alterations with ADC correlate even when T2 hyperintense lesions were detected in basal ganglia and/or thalami. Quantitative analysis demonstrated abnormal ADC values in all HUS patients with a trend to a greater number of affected regions in Subgroup A compared to Subgroup B (16 versus 11 median number of regions respectively, p = 0.56). Conclusion: Using DWI qualitative and quantitative differences were found between HUS patients showing poor neurological outcome and those without neurological deficits at discharge. While ADC values indicated more extensive cerebral changes than conventional qualitative findings, both may provide early prognostic indicators for neurological outcome in pediatric HUS patients.

What is Known:• In patients with STEC-HUS and neurological symptoms, MRI may show hyperintense signals on T2 and altered diffusivity mostly affecting basal ganglia, thalami and periventricular white matter.

What is New:• In such patients, early MRI including quantitative ADC measurements over different brain regions may allow for detection of signal alterations possibly reflecting microstructural changes in such patients.
Multimodal diffusion model for increments of electroencephalogram data
Authors: Leonenko N. N. , Salinger Z. , Sikorskii A. , Šuvak N. , Boivin M. J. 
Published: August 2023

AbstractWe propose a new strictly stationary strong mixing diffusion model with marginal multimodal (three-peak) distribution and exponentially decaying autocorrelation function for modeling of increments of electroencephalogram data collected from Ugandan children during coma from cerebral malaria. We treat the increments as discrete-time observations and construct a diffusion process where the stationary distribution is viewed as a mixture of three non-central generalized Gaussian distributions and we state some important properties related to the moments of this mixture. We estimate the distribution parameters using the expectation-maximization algorithm, where the added shape parameter is estimated using the higher order statistics approach based on an analytical relationship between the shape parameter and kurtosis. The derived estimates are then used for prediction of subsequent neurodevelopment and cognition of cerebral malaria survivors using the elastic net regression. We compare different predictive models and determine whether additional information obtained from multimodality of the marginal distributions can be used to improve the prediction.
L-fuzzy filters on complete residuated lattices
Authors: Ramadan Ahmed A. 
Published: August 2023

AbstractThis paper is toward the establishment of relationships between L-fuzzy filters, L-fuzzy topological spaces and L-fuzzy pre-proximity spaces in complete residuated lattices. We have demonstrated the existence of functors between the categories of L-fuzzy filter spaces, L-fuzzy topological spaces and L-fuzzy pre-proximity spaces.
Design, implementation and evaluation of a network-oriented service with environmental adaptability based on core/periphery structure
Authors: Takagi Shiori , Arakawa Shin’ichi , Murata Masayuki 
Published: August 2023

AbstractMany new network-oriented services have been developed in recent years, and they are expected to be virtualized in multi-access edge computing (MEC) environments, which are being standardized along with fifth generation (5 G). Because many new network-oriented services have been developed to meet various user requests, and service-oriented development, wherein service functions are divided and combined, is expected to facilitate the development of flexible services at low costs. A core/periphery structure is an information processing system in biological systems consisting of core units, that is densely connected and provide efficient process, and peripheral units that can accommodate a variety of inputs and outputs. In this paper, we introduce a core/periphery structure into the service design since the service based on this structure can adapt to various inputs and outputs with only modifying peripheral functions. We expect that development cost is reduced by designing services based on core/periphery structure, because the entire service is not modified against environmental changes. Besides, we also consider the balance between the penalty and the reduction of development costs since dividing functions and placing them in different devices creates extra communication paths and degrades service responsiveness. We designed and implemented two service scenarios for our shopping service with a remote robot based on a core/periphery structure. Using the implemented services, we show that the design using the core/periphery structure is effective in terms of implementation cost and overhead for information sharing among remote robots. Furthermore, we measured the penalty through experiments on actual devices and showed that it is tolerable.