bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH PEMBERIAN MASSAGE ABDOMEN TERHADAP KONSTIPASI PADA PASIEN STROKE NON HEMORAGIK
Authors: Ferry  , Khomsah Ida Yatun 
Published: March 2023

Stroke non hemoragik adalah gangguan peredaran darah ke otak yang dapat menimbulkan kerusakan pusat gerakan motorik di lobus frontalis sehingga akan mengalami gangguan mobilisasi yang dapat menyebabkan konstipasi. Konstipasi merupakan pelambatan pengeluaran isi fekal dari rektum dengan menghasilkan feses yang keras, kering, dan volume yang lebih kecil dari normal, dengan adanya penerapan terapi Massage Abdomen dapat mengurangi konstipasi. Dalam terapi ini dapat merangsang pristaltik usus serta memperkuat otot-otot abdomen yang akan membantu sistem pencernaan. Penelitian ini bertujuan untuk mengetahui pengaruh massage abdomen dalam mengatasi konstipasi pada pasien stroke non hemoragik berdasarkan literature review.
Desain penelitian yang digunakan adalah studi literature review, dengan kriteria literature Konstipasi, Massage Abdomen, Stroke Non Hemoragik.Hasil dari 5 jurnal menunjukkan bahwa Pengaruh Pemberian Massage Abdomen terhadap Konstipasi pada Pasien Stroke Non Hemoragik efekif menurunkan tingkat konsipasi dengan hasil p-value <0,05.Jurnal 1 menggunakan analisis teknik Uji t-independent, jurnal 2 menggunakan uji Wilcoxon dan uji Mann Whitney, jurnal 3 menggunakan teknik Independent t-test, jurnal 4 menggunakan uji T, jurnal 5 menggunakan uji ANOVA.Massage Abdomen merupakan teknik relaksasi yang dapat mempercepat reabsorbsi fases di kolon dan dapat meningkatkan frekuensi buang aing besar, sehingga dalam terapi komplementer ini memiliki fungsi yang dapat mengurangi masalah konstipasi pada pasien stroke non hemoragik.
EFEKTIFITAS KOMPRES HANGAT TERHADAP PENURUNAN SUHU TUBUH PADA ANAK DENGAN TYPHOID
Authors: Wulandari Yanti , Nuriman Arif 
Published: March 2023

Demam typhoid merupakan penyakit yang menyerang usus halus, demam typhoid masih menjadi penyakit endemik di Indonesia, salah satu masalah keperawatan yang dapat muncul berdasarkan tanda dan gejala diatas adalah hipertermia. Demam (hipertermi) adalah keadaan dimana suhu tubuh lebih tinggi dari biasanya dan dapat membahayakan apabila tidak ditangani sendiri salah satunya penanganan dengan cara kompres air hangat untuk menurunkan suhu tubuh. Tujuan penelitian ini adalah mengindentifikasi keefektifan kompres hangat terhadap penurunan suhu tubuh pada anak dengan typhoid. Jenis penelitian ini adalah studi literature review dengan cara mengumpulkan hasil penelusuran jurnal secara online. Desain penelitian menggunakan quasi eksperimen dengan rancangan pre and post test design. Hasil literatur riview yang dilakukan pada 5 artikel didapatkan hasil yaitu bahwa nilai rata-rata suhu tubuh sebelum dilakukan penerapan kompres hangat berkisar antara 37,8°C - 39°C. Rata-rata suhu tubuh sesudah dilakukan penerapan kompres hangat berkisar antara 36°C - 37,27 °C. Penerapan kompres hangat efektif untuk menurunkan suhu tubuh pada anak dengan typhoid dengan nilai p-value < 0,05. Penerapan kompres hangat terhadap penurunan suhu tubuh pada anak dengan typhoid sangat efektif, dapat diterapkan jiga anak mengalami demam, perlu dilakukan penelitian lanjutan membandingkan kompores hangat dan water tepid sponge di area axilla dan frontal serta membandingka keefektifan kompres hangat dan kompres dingin pada anak dengan typhoid.
PENERAPAN RELAKASASI NAFAS DALAM TERHADAP PENURUNAN TEKANAN DARAH PADA PASIEN HIPERTENSI
Authors: Khomsah Ida Yatun , Sri Wulan Sarinah 
Published: March 2023

ABSTRACT

Hypertension is a non-communicable disease which is a serious health problem and needs to be watched out for. Relaxation therapy can lower blood pressure without any side effects or contraindications such as therapy using antihypertension drugs. Through deep breathing relaxation, it will automatically stimulate the sympathetic nervous system to reduce levels of catecholamines, when the activation of the sympathetic nervous system decreases due to the relaxing effect, the production of catecholamines substances will decrease causing dilatation of of blood vessels and ultimately decreasing blood pressure. The purpose of this literature study is to describe deep breathing relaxation for reducing blood pressure in hypertension patients. The type of literature used is a literature review study design. The literature results from reducing journals 1,2,3,4 and 5 show that after the deep breathing relaxation is performed on patients with hypertension there is a decrease in blood pressure. The conclusion is that there is a decrease in blood pressure after doing deep breathing relaxation in hypertension patients.

Keywords: Hypertension, Blood Pressure Decreased, Deep Breathing Relaxation

ABSTRAK

Hipertensi menjadi salah satu penyakit tidak menular yang merupakan suatu masalah kesehatan serius dan perlu di waspadai. Terapi relaksasi dapat menurunkan tekanan darah tanpa adanya efek samping atau kontra indikasi seperti pada terapi dengan menggunakan obat anti hipertensi. Melalui relaksasi nafas dalam secara otomatis akan merangsang sistem saraf simpatis untuk menurunkan kadar zat ketokolamin, ketika aktivasi sistem saraf simpatis turun karena efek relaksasi maka produksi zat katekolamin akan berkurang sehingga menyebabkan dilatasi pembuluh darah dan akhirnya tekanan darah menurun. Tujuan studi literature ini untuk menggambarkan relaksasi nafas dalam terhadap penurunan tekanan darah pada pasien hipertensi. Jenis literature yang digunakan yaitu desain studi literature review Hasil literature dari mereduksi jurnal 1,2,3,4 dan 5 menunjukkan bahwa setelah dilakukannya teknik relaksasi nafas dalam terhadap pasien yang mengalami hipertensi terdapat penurunan tekanan darah. Kesimpulan ada penurunan tekanan darah setelah dilakukannya relaksasi nafas dalam pada pasien hipertensi.

Kata Kunci : Hipertensi, Penurunan Tekanan Darah, Relaksasi Nafas Dalam
FAKTOR – FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN STUNTING PADA BALITA
Authors: Wulandari Yanti , Arianti Mery 
Published: March 2023

Masa balita adalah periode yang penting dalam tumbuh kembang anak, masa balita dapat menentukan tahap perkembangan anak di masa datang. Stunting pada balita adalah dampak dari tidak tercukupi nutrien selama seribu hari pertama kehidupan balita. Ada beberapa faktor yang dapat menyebabkan stunting diantaranya adalah faktor ASI Ekslusif, status ekonomi, dan pendidikan ibu. Desain yang digunakan dalam penelitian adalah studi literature review, dengan kriteria faktor – faktor yang mempengaruhi stunting balita. Sebanyak 5 artikel yang terpilih digunakan dalam penulisan literature. Analisis dari kelima jurnal tersebut mendapatkan hasil akhir yang seragam bahwasanya faktor – faktor yang mempengaruhi stunting pada balita adalah pemberian ASI, sosial ekonomi & pendidikan ibu. Analisis Jurnal 1,2, 3, 4 dan 5 menggunakan analisis uji chi- square dengan case control. Kesimpulan yang didapatkan faktor – faktor yang mempengaruhi stunting pada balita adalah pemberian ASI, sosial ekonomi & pendidikan ibu. Hal ini dapat diminimalisir guna meningkatkan kualitas pertumbuhan dan perkembangan balita di masa datang.
İSKER ŞEHRİ’NDE GERÇEKLEŞTİRİLEN ARKEOLOJİK ARAŞTIRMALAR DOĞRULTUSUNDA ŞEHRİN YAPISI VE SİBİR TATARLARINA AİT BAZI BULUNTULAR
Authors: YILMAZ Mecnun 
Published: March 2023

Sibir Tatarları tarafından 14. yüzyılın ortalarında Batı Sibirya’daki günümüz Tobolsk şehri yakınlarında kurulan ve Sibir Hanlığı’na 1495 yılından itibaren başkentlik yapmaya başlayan İsker, 1588 yılında merkezî Rus kuvvetleri tarafından ele geçirilinceye kadar bölgedeki varlığını sürdürmüştür. Bu olayın ardından şehir, yerleşime açılmamış ve zaman içerisinde yıkılmaya yüz tutmuştur. Nitekim tarihî önemini yitirmeyen şehir, yüzey inceleme ve kazı yöntemleri bazen ayrı ayrı bazen de bir arada kullanılarak çeşitli arkeolojik araştırmalara tabi tutulmuştur.
Bu suretle çalışmamızda, N. G. Spafariy, S. U. Remezov, G. F. Miller, M. S. Znamenskiy, İ. N. Butakov, V. N. Pignatti, A. F. Palaşenkov, A. P. Zıkov ve A. A. Adamov tarafından farklı zamanlarda İsker’de gerçekleştirilen arkeolojik araştırmalar hakkındaki bilgilere yer verilecektir. Ayrıca şehrin kapladığı alanın zaman içerisindeki değişimine, şehrin tahkimat yapılarına, şehirdeki konutların hangi malzemelerden yapıldığına ve kazı çalışmaları sonucunda elde edilen Sibir Tatarlarına ait çeşitli tarım aletlerine, bıçaklara, ok uçlarına, yüzüklere dair teknik ve kültürel açıdan birtakım değerlendirmelerde bulunulacaktır.
Aide médicale à mourir pour les personnes inaptes à consentir à la suite d’un trouble neurocognitif majeur : préoccupations de travailleurs sociaux du Québec
Authors: Bravo Gina , Delli-Colli Nathalie , Dumont Isabelle , Bouthillier Marie-Eve , Rochette Marianne , Trottier Lise 
Published: March 2023

L’aide médicale à mourir (AMM) n’est pas accessible, à ce jour, aux personnes inaptes à consentir à la suite d’un trouble neurocognitif majeur qui l’auraient demandée de façon anticipée. Un questionnaire destiné aux travailleurs sociaux a été conçu pour évaluer l’acceptabilité d’étendre l’AMM à cette population. Une analyse quantitative des réponses, déjà publiée (Bravo et al., 2022) montre que la majorité des travailleurs sociaux appuie l’idée de donner aux personnes inaptes accès à l’AMM. Le présent article rapporte les résultats d’une analyse qualitative des commentaires laissés par les répondants à la fin du questionnaire, à travers lesquels ils expriment des préoccupations. Des 367 questionnaires retournés, 162 incluent des commentaires. Les principales préoccupations soulevées ont trait aux difficultés d’application des demandes anticipées, au risque d’abus et à l’incapacité du système de santé de répondre aux besoins des personnes qui vivent avec un trouble neurocognitif majeur. Advenant la légalisation des demandes anticipées d’AMM, les travailleurs sociaux souhaitent être impliqués dans le processus, être formés et être soutenus dans leurs démarches.
Development of a new generation of miniemulsion based on cottonseed oil with α-tocopherol and ZnO and evaluation of its adjuvant activity
Authors: Sobrevilla-Hernández Gustavo , Franco-Molina Moisés Armides , Zárate-Triviño Diana G. , Kawas Jorge R. , Hernández-Martínez Sara Paola , García-Coronado Paola Leonor , Santana-Krímskaya Silvia Elena , Alvizo-Báez Cynthia Aracely , Rodríguez-Padilla Cristina 
Published: March 2023

Background
Emulsions have been widely used as immunological adjuvants. But the use of materials derived from plants such as cottonseed oil, alpha-tocopherol, or minerals such as zinc, as well as their use at the nanometric scale has been little explored. In this study, we develop a new miniemulsion and evaluated its antioxidant and phagocytic capacity, as well as parameters related to immune response stimulation by cytokine expression and antibodies production in a mice model.

Methods
Formulated CN (cottonseed oil miniemulsion) and CNZ (cottonseed oil miniemulsion whit zinc oxide nanoparticles) miniemulsions were characterized by scanning electronic microscopy SEM, DLS and FT-IR. In murine macrophages, splenocytes and thymocytes primary cultures safety and cytotoxicity were determined by MTT. In macrophages the antioxidant and phagocytic capacity was evaluated. In BALB/c mice, the stimulation of the immune system was determined by the expression of cytokines and the production of antibodies.

Results
The CN and CNZ presented stability for 90 days. Immediately after preparation, the CN presented a higher particle size (543.1 nm) than CNZ (320 nm). FT-IR demonstrated the correct nanoparticle synthesis by the absence of sulfate groups. CN and CNZ (1.25 to 10 µL/mL) had no toxic effect on macrophages (p = 0.108), splenocytes (p = 0.413), and thymocytes (p = 0.923). All CN and CNZ doses tested induced nitric oxide and antioxidants production in dose dependent manner when compared with control. CN-ovalbumin and CNZ-ovalbumin treatments in femoral subcutaneous tissue area showed inflammation with higher leukocyte infiltration compared with FCA. The intraperitoneal administration with CN, CNZ, and FCA showed a higher total intraperitoneal cells recruitment (CD14+) after 24 h of inoculation than control (p = 0.0001). CN and CNZ increased the phagocyte capacity with respect to untreated macrophages in the Candida albicans-phagocytosis assay. The evaluation of residual CFU indicated that only CN significantly decreased (p = 0.004) this value at 3 h. By other side, only CN increased (p = 0.002) the nitric oxide production. CNZ stimulated a major INFγ secretion compared with FCA at day 7. A major IL-2 secretion was observed at days 7 and 14, stimulated with CN and CNZ. Both miniemulsions did not affect the antibody isotypes production (IgG1, IgG2a, IgG3, IgA and IgM) at days 7, 14, 28, and 42. CN induced a significant IgG production against OVA, but lesser than FCA.

Conclusions
The two new miniemulsions with adjuvant and antioxidant capacity, were capable of generating leukocyte infiltration and increased cytokines and antibodies production.
Wastewater monitoring of SARS-CoV-2 RNA at K-12 schools: comparison to pooled clinical testing data
Authors: Kim Sooyeol , Boehm Alexandria B. 
Published: March 2023

Background
Wastewater measurements of SARS-CoV-2 RNA have been extensively used to supplement clinical data on COVID-19. Most examples in the literature that describe wastewater monitoring for SARS-CoV-2 RNA use samples from wastewater treatment plants and individual buildings that serve as the primary residence of community members. However, wastewater surveillance can be an attractive supplement to clinical testing in K-12 schools where individuals only spend a portion of their time but interact with others in close proximity, increasing risk of potential transmission of disease.

Methods
Wastewater samples were collected from two K-12 schools in California and divided into solid and liquid fractions to be processed for detection of SARS-CoV-2. The resulting detection rate in each wastewater fraction was compared to each other and the detection rate in pooled clinical specimens.

Results
Most wastewater samples were positive for SARS-CoV-2 RNA when clinical testing was positive (75% for solid samples and 100% for liquid samples). Wastewater samples continued to test positive for SARS-CoV-2 RNA when clinical testing was negative or in absence of clinical testing (83% for both solid and liquid samples), indicating presence of infected individuals in the schools. Wastewater solids had a higher concentration of SARS-CoV-2 than wastewater liquids on an equivalent mass basis by three orders of magnitude.
Risk of Stroke, Death, and Myocardial Infarction Following Transcarotid Artery Revascularization vs Carotid Endarterectomy in Patients With Standard Surgical Risk
Authors: Liang Patric , Cronenwett Jack L. , Secemsky Eric A. , Eldrup-Jorgensen Jens , Malas Mahmoud B. , Wang Grace J. , Nolan Brian W. , Kashyap Vikram S. , Motaganahalli Raghu L. , Schermerhorn Marc L. 
Published: March 2023

ImportanceCarotid artery stenting has been limited to use in patients with high surgical risk; outcomes in patients with standard surgical risk are not well known.ObjectiveTo compare stroke, death, and myocardial infarction outcomes following transcarotid artery revascularization vs carotid endarterectomy in patients with standard surgical risk.Design, Setting, and ParticipantsThis retrospective propensity-matched cohort study was conducted from August 2016 to August 2019 with follow-up until August 31, 2020, using data from the multicenter Vascular Quality Initiative Carotid Artery Stent and Carotid Endarterectomy registries. Patients with standard surgical risk, defined as those lacking Medicare-defined high medical or surgical risk characteristics and undergoing transcarotid artery revascularization (n = 2962) or carotid endarterectomy (n = 35 063) for atherosclerotic carotid disease. In total, 760 patients were excluded for treatment of multiple lesions or in conjunction with other procedures.ExposuresTranscarotid artery revascularization vs carotid endarterectomy.Main Outcomes and MeasuresThe primary outcome was a composite end point of 30-day stroke, death, or myocardial infarction or 1-year ipsilateral stroke.ResultsAfter 1:3 matching, 2962 patients undergoing transcarotid artery revascularization (mean [SD] age, 70.4 [6.9] years; 1910 [64.5%] male) and 8886 undergoing endarterectomy (mean [SD] age, 70.0 [6.5] years; 5777 [65.0%] male) were identified. There was no statistically significant difference in the risk of the primary composite end point between the 2 cohorts (transcarotid 3.0% vs endarterectomy 2.6%; absolute difference, 0.40% [95% CI, −0.43% to 1.24%]; relative risk [RR], 1.14 [95% CI, 0.87 to 1.50]; P = .34). Transcarotid artery revascularization was associated with a higher risk of 1-year ipsilateral stroke (1.6% vs 1.1%; absolute difference, 0.52% [95% CI, 0.03 to 1.08]; RR, 1.49 [95% CI, 1.05 to 2.11%]; P = .02) but no difference in 1-year all-cause mortality (2.6% vs 2.5%; absolute difference, −0.13% [95% CI, −0.18% to 0.33%]; RR, 1.04 [95% CI, 0.78 to 1.39]; P = .67).Conclusions and RelevanceIn this study, the risk of 30-day stroke, death, or myocardial infarction or 1-year ipsilateral stroke was similar in patients undergoing transcarotid artery revascularization compared with those undergoing endarterectomy for carotid stenosis.
Effectiveness of Structured Care Coordination for Children With Medical Complexity
Authors: Cohen Eyal , Quartarone Samantha , Orkin Julia , Moretti Myla E. , Emdin Abby , Guttmann Astrid , Willan Andrew R. , Major Nathalie , Lim Audrey , Diaz Sanober , Osqui Lisa , Soscia Joanna , Fu Longdi , Gandhi Sima , Heath Anna , Fayed Nora 
Published: March 2023

ImportanceChildren with medical complexity (CMC) have chronic conditions and high health needs and may experience fragmented care.ObjectiveTo compare the effectiveness of a structured complex care program, Complex Care for Kids Ontario (CCKO), with usual care.Design, Setting, and ParticipantsThis randomized clinical trial used a waitlist variation for randomizing patients from 12 complex care clinics in Ontario, Canada, over 2 years. The study was conducted from December 2016 to June 2021. Participants were identified based on complex care clinic referral and randomly allocated into an intervention group, seen at the next available clinic appointment, or a control group that was placed on a waitlist to receive the intervention after 12 months.InterventionAssignment of a nurse practitioner–pediatrician dyad partnering with families in a structured complex care clinic to provide intensive care coordination and comprehensive plans of care.Main Outcomes and MeasuresCo-primary outcomes, assessed at baseline and at 6, 12, and 24 months postrandomization, were service delivery indicators from the Family Experiences With Coordination of Care that scored (1) coordination of care among health care professionals, (2) coordination of care between health care professionals and families, and (3) utility of care planning tools. Secondary outcomes included child and parent health outcomes and child health care system utilization and cost.ResultsOf 144 participants randomized, 141 had complete health administrative data, and 139 had complete baseline surveys. The median (IQR) age of the participants was 29 months (9-102); 83 (60%) were male. At 12 months, scores for utility of care planning tools improved in the intervention group compared with the waitlist group (adjusted odds ratio, 9.3; 95% CI, 3.9-21.9; P &amp;lt; .001), with no difference between groups for the other 2 co-primary outcomes. There were no group differences for secondary outcomes of child outcomes, parent outcomes, and health care system utilization and cost. At 24 months, when both groups were receiving the intervention, no primary outcome differences were observed. Total health care costs in the second year were lower for the intervention group (median, CAD$17 891; IQR, 6098-61 346; vs CAD$37 524; IQR, 9338-119 547 [US $13 415; IQR, 4572-45 998; vs US $28 136; IQR, 7002-89 637]; P = .01).Conclusions and RelevanceThe CCKO program improved the perceived utility of care planning tools but not other outcomes at 1 year. Extended evaluation periods may be helpful in assessing pediatric complex care interventions.Trial RegistrationClinicalTrials.gov Identifier: NCT02928757
Tissue and plasma enzyme activities and chemical analytes in Golden Trevally from a public aquarium
Authors: Rapp Kathryn , Perry Sean , Delaune Alexa , Stilwell Justin 
Published: March 2023

Abstract

Objective
Veterinary care of aquatic species, particularly fish, is limited by a lack of knowledge regarding their unique physiology. Tissue enzyme activities measured in plasma are used for assessing function and potential damage to specific organs and tracking disease progression in live animals. The objective of this study was to identify tissue(s) of origin and plasma concentrations for specific enzymes in healthy Golden Trevally Gnathanodon speciosus. We hypothesized that enzymes would exhibit tissue-specific tropisms, with higher activities in one or more tissues compared to others.

Methods
Six fish were randomly selected from a public aquarium population to obtain antemortem blood samples. The fish were then euthanized, and tissue samples were collected via gross necropsy. Six enzyme activities and two chemical analytes were examined across samples of plasma and 10 tissues from each fish.

Result
Enzyme activities exhibited significant organ specificities. Aspartate aminotransferase, lactate dehydrogenase, and creatine kinase levels were highest in skeletal muscle, with variably high levels in gonads. Alkaline phosphatase levels were highest in the kidney, spleen, and liver. Alanine aminotransferase levels had high specificity for the liver. Gamma-glutamyl transferase was only detectable in the kidney and plasma.

Conclusion
This work establishes baseline tissue enzyme origins for Golden Trevally, which will aid clinicians in diagnostic interpretation of blood chemistries and improve veterinary care for this understudied fish species.
An Anti‐Freezing Hydrogel Electrolyte for Flexible Zinc‐Ion Batteries Operating at −70 °C
Authors: Shi Ying , Wang Rui , Bi Songshan , Yang Min , Liu Lili , Niu Zhiqiang 
Published: March 2023

AbstractAqueous zinc‐ion batteries (ZIBs) are considered as the promising candidate of flexible energy storage devices due to their high safety, eco‐friendliness, and low‐cost. However, conventional flexible aqueous ZIBs undergo severe capacity loss at bending and subzero temperature states. Herein, an anti‐freezing hydrogel electrolyte based on zinc tetrafluoroborate (Zn(BF4)2) and polyacrylamide (PAM) is developed. Owing to the strong electronegativity of F atoms, BF4−anions interact with water molecules by OH···F to replace the OH···O between water molecules in Zn(BF4)2‐PAM hydrogel electrolyte, inhibiting the formation of ice crystal lattice in hydrogel electrolyte at low‐temperature. Therefore, the Zn(BF4)2‐PAM hydrogel remains unfrozen state, good flexibility, and high ionic conductivity even at −70 °C, which ensures that they can act as the electrolytes of anti‐freezing flexible ZIBs. As a proof of concept, anti‐freezing flexible ZIBs with all‐in‐one integrated configuration are assembled based on Zn(BF4)2‐PAM hydrogel. They display enhanced electrochemical performance at −70 °C, such as high capacity retention and remarkable cyclic stability. Furthermore, they also maintain stable electrochemical performance under different bending states even at −70 °C. This work broadens the practical application of flexible aqueous ZIBs at ultralow temperature.