bluuebunny/crossref_metadata_2025_split huggingface dataset:
Penegakan Hukum Pembatasan Sound Pressure Level Pada Karnaval Sound System
Authors: Wijaya Indra 
Published: July 2023

The protection of human rights and just welfare are Indonesia's orientation as a rule of law country. In line with developments and civilization, parade activities that should show our customary wealth and cultural identity are beginning to be eroded by sound system parades which tend to cause social problems in society, conflicts and even physical damage and health problems caused by the loud sound of a powerful sound system. The purpose of this study is to discuss law enforcement against limiting sound pressure levels in the hope that new arrangements can be realized. The research uses a normative juridical method with a qualitative aPeraturan Pemerintahroach that is descriptive in Law No. 32 of 2009 concerning Environmental Protection and Management. From the research conducted, findings were obtained based on statutory regulations No. 32 of 2009 regarding the enforcement of sound pressure level restrictions that have been regulated and emphasized by Peraturan Pemerintah No. 48 of 1996 concerning noise level standards and Peraturan Pemerintah No. 60 of 2017 concerning procedures for licensing and monitoring crowd activities general up to the Chief of Police's field instructions No. Pol / 02 / XII / 95 regarding licensing and notification of community activities cannot yet be implemented. Found in the Chief of Police's field instructions No. Pol / 02 / XII / 95 has not been clearly regulated regarding licensing, it only lists parade activities but there are no further arrangements.
Pengembangan Perangkat Pembelajaran Model Blender (Blended Learning) untuk Membangun Pemahaman Materi Fungsi
Authors: Rohman Nur , Junarti Junarti , Pangestu Ari Yoga 
Published: July 2023

Abstrak: Penelitian ini merupakan penelitian yang mengembangkan perangkat pembelajaran matematika menggunakan model Blended Learning (BLENDER) pada materi limit fungsi aljabar. Latar belakang penelitian ini adalah pembelajaran matematika cenderung menggunakan metode ceramah dan siswa belum terlibat aktif dalam proses pembelajaran, selain itu dalam proses menghitung nilai limit siswa masih mengalami kesulitan. Penelitian ini bertujuan untuk mengembangkan perangkat pembelajaran matematika, mendeskripsikan kualitas perangkat pembelajaran model Blended Learning dan mengetahui respon siswa terhadap proses pembelajaran matematika pada materi limit fungsi aljabar. Penelitian ini menggunakan model ADDIE yang meliputi: (1) tahap analisis (Analisys), (2) tahap perancangan (Design), (3) tahap pengembangan (Development), (4) tahap penggunaan (Implementation), dan (5) tahap evaluasi (Evaluation). Prangkat pembelajaran yang dikembangkan adalah silabus dan RPP. Subjek penelitian ini adalah siswa kelas XII TEI SMK Negeri 2 Bojonegoro. Objek penelitian adalah semua perangkat pembelajaran yang dikembangkan oleh peneliti. Teknik pengumpulan data yang digunakan adalah observasi dan wawancara. Hasil penelitian menunjukan bahwa: 1) Perangkat pembelajaran telah berhasil dikembangkan dengan menggunakan model ADDIE, 2) Hasil validasi peragkat pembelajaran adalah 4 termasuk kategori baik. Hasil ketuntasan siswa mencapai 91,4 % kategori sangat baik, 3) Hasil kuesioner respon siswa terhadap proses pembelajaran dengan menggunakan model Blended Learning memperoleh hasil 82,9 % termasuk dalam kategori baik. Guru merasa terbantu dalam melaksanakan pembelajaran dengan menggunakan model Blended Learning.
Kata kunci: Perangkat pembelajaran BLENDER; model Blended Learning; Limit Fungsi Aljabar
Kemampuan Reprensentasi Visual Mahasiswa PGSD Pada Mata Kuliah Statistik Pendidikan
Authors: Sugiyono Sugiyono 
Published: July 2023

Penelitian ini bertujuan untuk menganalisis kemampuan representasi visual mahasiswa program studi Pendidikan Guru Sekolah Dasar dalam menyajikan data pada mata kuliah Statistik Pendidikan. Penelitian ini merupakan penelitian deskriptif kualitatif dengan subjek penelitian adalah mahasiswa program studi Pendidikan Guru Sekolah Dasar STKIP PGRI Pacitan. Data dikumpulkan dari hasil jawaban mahasiswa dalam membuat tabel, diagram lingkaran, dan diagram batang. Analisis data menggunakan model analisis interaktif yang meliputi pengumpula data, reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian ini menunjukkan bahwa kemampuan representasi visual mahasiswa dalam membuat tabel distribusi frekuensi baik dengan menggunakan aplikasi komputer maupun menggambar manual memenuhi indikator representasi visual. Dalam mengilustrasikan diagram lingkaran dengan menggunakan aplikasi komputer memenuhi indikator representasi visual, sedangkan mahasiswa yang menggambar manual tidak memenuhi indikator. Dan dalam mengilustrasikan diagram batang menggunakan aplikasi komputer tidak memenuhi indikator, sedangkan mahasiswa yang menggambar manual memenuhi indikator representasi visual.
Polcy Breif Penanganan Stunting di Kota Surabaya: Perspektif Pendidikan dan Kesehatan Masyarakat
Authors: Mukodi Mukodi , Rahmawati Deti 
Published: July 2023

Penelitian ini bertujuan untuk; (1) mendeskripsikan dan menganalisis kebijakan penanganan 1000 HPK (Hari Pertama Kehidupan) di Kota Surabaya; (2) mendeskripsikan dan menganalisis penanganan Stunting di bidang pendidikan dan bidang kesehatan; (3) mendeskripsikan dan menganalisis faktor pendukung dan penghambat kebijakan penanganan stunting di Kota Surabaya. Jenis penelitian ini adalah penelitian deskriptif kualitatif. Obyek penelitiannya di Kampung KB Putat Jaya dan Kampung KB Kali Rungkut. Metode pengumpulan penelitian ini dilakukan dengan observasi, wawancara mendalam, dan dokumentasi. Teknik analisis data menggunakan alur analisis versi Miles dan Huberman, yaitu reduksi data, penyajian data, dan penarikan kesimpulan. Penanganan 1000 HPK Kota Surabaya sudah tepat, optimal dan sesuai dengan perencanaan. Indikatornya, penanganan didasarkan pada bentuk intrevensi spesifik dan intervensi sensitif sesuai sasaran balita yang mengalami stunting, yakni di Kampung KB Putat Jaya dan Kampung KB Kali Rungkut. Di sisi yang sama, penanganan di lakukan secara sistemik berorientasi pada bidang pendidikan berupa sosialisasi dan edukasi penanganan stunting bagi keluarga terimbas. Kemudian, dilakukan pula pada bidang kesehatan, berupa penyuluhan, dan beragam bantuan untuk memotong mata rantai stunting. Penurunan angka agregat stunting di Kelurahan Putat Jaya sebanyak 223% dan Kelurahan Kali Rungkut sebanyak 276% pada 2022 hingga 2023 merupakan wujud keseriusan Kota Surabaya dalam menekan dan mengatasi kasus stunting melalui berbagai program kebijakan. Penanganan stunting di Kota Surabaya dalam perspektif pendidikan dilakukan dengan cara edukasi dan sosialisasi bagaimana cara pencegahan serta penanganan tindakan pada kasus balita stunting di lokus sasaran yang ditetapkan. Kemudian, penanganan stunting dalam perspektif kesehatan melalui penyuluhan dan fasilitasi kesehatan bagi balita dan orang tua penderita stunting di lokusnya.
A protocol to enumerate total and viable bacterial cells using QUANTOM Tx ™ Microbial Cell Counter
Authors: Bainbridge-Sedivy Rachel , Naushad Sohail , Firth Isaac , Gymninova Irina , El-Azouni Maram , Edissi Sofia , Kang Mingsong , Thanthrige-Don Niroshan , Lam Cindy , Huang Hongsheng 
Published: July 2023

Abstract
Accurate quantification of viable and non-viable bacteria is fundamental to most microbiological studies, thus, rapid and simple techniques are required for this purpose. The current protocol describes a procedure using the QUANTOM Tx™ Microbial Cell Counter (Logos Biosciences Ltd., Korea), a novel instrument for the quantitative measurement of total and viable microbial cells in a solution, using several bacterial species including Listeria monocytogenes, Escherichia coli, Campylobacter jejuni and Brucella species.
PASSIVE FIT OF CAD\CAM FRAMEWORKS DESIGNED BASED ON VIRTUAL IMPLANT POSITIONS VERSUS ACTUAL IMPLANT POSITIONS: A PILOT INVITRO STUDY
Authors: Kamel Mohamed El-Sayed 
Published: July 2023

Abstract
Aim: To evaluate the passive fit of CAD/CAM implant supported frameworks that are constructed before and after implant placement.
Methodology: A sample of 5 Kennedy class I models that loaded with 10 models bilaterally. In the first group, 3 implants were installed using full guided protocol and loaded with 3 units screw retained metal framework that constructed before implant placement based on virtual implant positions in aid of full digital work flow. While the second group was the control group, in which 3 implant were installed and loaded with 3 units screw retained metal frameworks constructed after implant installation based on their implant positions. The frameworks were screwed to multi-unit abutments seven tests were carried out to assess passive fit of the frameworks. These tests were visual, tactile test using examination probe, floss slippage, one screw test , screw resistance test and fit checker. Radiographs were done in conjunction with these tests to assess presence of gaps at abutment –framework interface.
Droplet-based Single-cell Joint Profiling of Histone Modification and Transcriptome
Authors: Xie YANG , Zhu Chenxu , Wang Zhaoning , Tastemel Melodi , Chang Lei , Li Yang Eric , Ren Bing 
Published: July 2023

Abstract
We introduce Droplet Paired-Tag, a multiomic technique which enables rapid and convenient mapping of histone modifications and gene expression simultaneously at single-cell resolution on a large scale. Compared to other techniques, Droplet Paired-Tag shows outstanding efficacy in reconstructing cell type-specific active or repressive gene regulatory networks in both cultured mammalian cells and primary mouse brain tissues.
Phylogenetic relationships of five date palm (Phonex dactylifera L) in Al Ahsa, Kingdom of Saudi Arabia using RAPD markers through QIAxcel system
Authors: Ahamed Reyas , Algethami Jari S. , Alhamami Mohsen A. M. , Ramadan Mohamed F. , Abdallah Osama I. 
Published: July 2023

Abstract
Date palm (Phoenix dactylifera L.) is the sweetest edible fruit plant in the Kingdom of Saudi Arabia. The development of precise DNA fingerprints to identify cultivar's genetic diversity is most important for breeding programs. Genotypic variation among five different cultivars of date palm of the Al Ahsa governorate in Kingdom of Saudi Arabia was studied using random amplified polymorphic DNA (RAPD) markers by QIAxcel electrophoresis system. We test 20 RAPD primers among them 15 primers show banding pattern. We use clean younger leaves that had been gathered and grind with liquid nitrogen into a fine powder and used for extraction and ultimately the quality of the DNA. We examined the DNA extraction with the use of guide CTAB and automatic Qiagen EZ1 technique and tested using the UV gel electrophoresis the concentration of the DNA became examined with LABTRON Nano spectrophotometer. Four primers gave high levels of bands with numerous polymorphisms and multiple bands. A total of 165 bands were observed, including 89 polymorphisms and 4 monomorphisms. The Ruzeiz(RZ) breed is very closely related to Khalas(KH), but the recorded Ruzeiz(RZ) and Shebebi(SHB) breeds retain a high degree of genetic divergence between Hatimi(HT) and Shaishe(SH). The results of this study demonstrate that polymorphisms revealed using RAPD markers are genotype appropriate.
Morphological and genetic variability in cosmopolitan tardigrade species - Paramacrobiotus fairbanksi Schill, Förster, Dandekar &amp; Wolf, 2010
Authors: Kayastha Pushpalata , Szydło Wiktoria , Mioduchowska Monika , Kaczmarek Łukasz 
Published: July 2023

Abstract
Paramacrobiotus fairbanksi was described from Alaska (USA) based on integrative taxonomy and later reported from various geographical locations making it a true cosmopolitan species. The ‘Everything is Everywhere’ (EiE) hypothesis assumes that microscopic organisms have unique features that help them to inhabit many different environments, meaning they can be considered cosmopolitan. In the present work we report four new populations of Pam. fairbanksi from the Northern Hemisphere which suggests that the ‘EiE’ hypothesis is true, at least for some tardigrade species. We also compared all known populations of Pam. fairbanksi at the genetic and morphological levels. The p-distances between COI haplotypes of all sequenced Pam. fairbanksi populations from Albania, Antarctica, Canada, Italy, Madeira, Mongolia, Spain, USA and Poland ranged from 0.002% to 0.005%. In total, twelve haplotypes (H1-H12) of COI gene fragments were identified. We also report statistically significant morphometrical differences of species even though they were cultured and bred in the same laboratory conditions, and propose epigenetic factor as a main cause rather than temperature, predation risk and food availability. Furthermore, we also discuss differences in the potential distribution of two Paramacrobiotus species.
Meropenem versus Ceftazidime-Avibactam versus Ceftazidime-Avibactam with Aztreonam as empiric, first-line treatment of high-risk febrile neutropenia: first report of the CAMerA Trial, an open-labelled, randomized-controlled trial.
Authors: Jadhav Sachin Suresh , Jyothi Goutham Kumar , Matani Anjali , Panchal Amey C , Ojha Nishit , Tony Sonu , Naik Yesheswini N 
Published: July 2023

Abstract
Introduction: Infections due to extended spectrum beta-lactam (ESBL) positive, carbapenemase producing enterobacteriaceae (CPE) and NDM1 resistance Enterobacteriaceae have significantly increased internationally and may account for up to 70% of infections in some geographies. Parallelly, high colistin resistance rates have also been reported. We are reporting the initial results of the first randomized-controlled trial addressing this issue of antibiotic resistant Gram-negative bacteremia (GNB).
Objectives: The objective of the study was to assess the efficacy of first-line Ceftazidime–Avibactam with or without Aztreonam in high-risk FN, versus meropenem.
Methodology: Adult patients with high-risk FN were randomized to Meropenem, Ceftazidime-Avibactum or Ceftazidime-Avibactum with Aztreonam as the first line antibiotic regimen.
Results: Compared to meropenem, there was a trend towards reduced antibiotic failure, as defined by breakthrough fever within 7 days, with ceftazidime-avibactam, with or without aztreonam, although this wasn’t statistically significant, (p value = 0.076). Besides this, antibiotic failure was significantly associated with blood culture positivity (p= 0.015). Also, the presence of lung infiltrates was significantly associated with transfer to ICU (p=0.001).
Conclusion: In high-risk FN, there was a trend to a higher incidence of antibiotic failure with first-line therapy with meropenem, compared to ceftazidime-avibactam with or without aztreonam, (p value = 0.076).
Transforming Tree Topping Waste into Flooring: A Study on the Production and Evaluation of Oriented Strand Board Finish using Urban and Garden Residues
Authors: Dastjerdi Mohammad Manafi , Rohani Abbas , Hosseinabadi Hamid Zarea , Nik Mohammadali Ebrahimi 
Published: July 2023

Abstract
Oriented strandboard (OSB) has become a popular building material for residential construction, but little research has been conducted on its use as a finish floor material. the study investigated the quality and performance of OSB as an alternative to traditional engineered wood products for finish floors. Four types of OSB finish floors using a mixture of garden and urban tree toppings were produced and evaluated, along with different types and levels of resin and mat moisture content. The finish floor panels were subjected to a battery of tests, including concentrated loading, indentation, falling-ball impact resistance, abrasion resistance, and surface wettability. The findings showed that urea formaldehyde resin with garden tree toppings performed best in floor surface indentation, abrasion resistance, and falling-ball indentation. The phenol formaldehyde resin with garden tree toppings, on the other hand, showed less moisture absorption and swelling during surface wetting tests and better resistance to force application in the concentrated loading test. Our qualitative comparison revealed that OSB finish floor production using 100% garden tree topping strands and 12% urea formaldehyde resin, along with 14% mat moisture content, produced the best results. this study provides valuable insights into the potential use of OSB as a sustainable and cost-effective finish floor material, using waste materials from urban and garden tree toppings.
Study on the formation process and mechanism of aerobic granular sludge in the Sequencing Batch Biofilter Granular Reactor
Authors: Lin Ling , Chen Shuangshuang , Hou Yi , Lei Lirong 
Published: July 2023

Abstract
SBBGR is a promising wastewater treatment technology because of its low sludge yield and good toxicity tolerance. However, little attention has been paid to the formation process of AGS in SBBGR and the mechanism of formation. In this study, aerobic granular sludge with good performance was successfully cultivated around day 40 by using synthetic wastewater as feed: the mixed liquid suspended solids and mixed liquor volatile suspended solids raised from 3.85 g/L and 1.85 g/L to 31.38 g/L and 24.74 g/L respectively, and the COD, TN, and TP removal efficiencies were respectively 91.21%, 84.99%, and 58.14%. The experimental results showed that Amoebacteria and Bacteroides phylum played an important role in the formation of aerobic granular sludge, filamentous bacteria act as the three-dimensional skeleton, surrounded by filling bacilli and rod-shaped bacteria, and PN plays a dominant role in promoting granulation during the culture process.
The study and application of space-time absolute nodal coordinate formulation quadrilateral cable element
Authors: Chen Dekun , Wang Yue , Lu Nianli , Lan Peng , Xue Yuan 
Published: July 2023

Abstract
The construction of high-order shape function is a key and difficulty for unstructured grid mesh and sliding boundary problem.
In this paper, a construction method of space-time absolute nodal coordinate formulation quadrilateral cable (SACQ) is proposed and the accuracy of SACQ element is studied and verified with 3 different applications.
First, the shape function of SACQ is constructed with spatiotemporal reduction coordinate and the action integral of SACQ is composed with Lagrangian function and discrete with perspective transformation.
second, numerical convergence region is discussed and determined with Courant number.
Furthermore, a space-time nodal dislocation and its relation with Courant number is studied.
The simulation and verification are focusing on some realistic problems.
Finally, one-sided impact, free-flexible pendulum, taut string with sliding boundary and a deployable guyed mast under impact transverse wave are simulated.
In these problems, unstructured grid meshed with SACQ has similar energy convergence and accuracy with structured grid but shows better efficiency.
GRK2 deficiency in vascular smooth muscle cellsexacerbates angiotensin II-induced aortic aneurysm formation by increasing vascular inflammation and TGFβRII degradation
Authors: chen shaoliang , ye peng , wang dongchen , kong chaohua , chao yuelin , jiang zihao , luo jie , yu wande , jiang xiaomin , zhu linlin , gu yue , zhang juan 
Published: July 2023

Abstract
Aortic aneurysm is a life-threatening complication of hypertension-induced cardiovascular dysfunction. Accumulating evidence has proven that G protein-coupled receptor kinase 2 (GRK2) is an important regulator of vascular remodelling and blood pressure. Genetic testing has shown that the expression of transforming growth factor-β type II receptor (TGFβRII) differs significantly between normal and aneurysm tissues. However, no evidence has proven that vascular smooth muscle cell (VSMC)-specific GRK2 deletion exacerbates aortic aneurysm formation. This study aimed to prove the involvement of GRK2 deficiency in aortic aneurysm pathogenesis n a manner dependent on TGFβRII degradation and increased inflammation. We found that GRK2 was downregulated in aneurysm tissues from patients with aortic dissection. Then, mice with VSMC-specific GRK2 deletion were implanted with a micro-osmotic pump containing angiotensin II (AngII) to induce hypertension. GRK2 deficiency led to an increased occurrence of aortic aneurysms, with a decrease in the TGFβR2II level, which enhanced elastin degradation and increased macrophage infiltration. We used adeno-associated virus to overexpress GRK2 in VSMCs in ApoE knock-out (ApoE-/-) mice. Upregulation of GRK2 significantly inhibited the expression of TGFβRII and alleviated aortic aneurysm progression. In vitro, knock-down of GRK2 reduced the cell membrane distribution of TGFβRII by promoting its ubiquitination. Moreover, conditioned medium (CM) from VSMCs with or without adenovirus-mediated GRK2 overexpression in the presence of AngII were used to stimulate macrophages. AngII-induced inflammation was reversed after treatment with CM from VSMCs treated with adenovirus. These findings also indicated an important and novel therapeutic strategy to inhibit aortic aneurysm progression.
Mutations in DEAD/H-box Helicase 11 Correlate with Increased Relapse Risk in Adults with Acute Myeloid Leukaemia with Normal Cytogenetics
Authors: Ruan Guo-Rui , Zhou Ya-Lan , Zhao Ming-Yue , Gale Robert , Jiang Hao , Jiang Qian , Liu Lixia , Qin Jiayue , Cao Shanbo , Lou Feng , Xu Lan-Ping , Zhang Xiao-Hui , Huang Xiao-Jun 
Published: July 2023

Abstract
People with acute myeloid leukaemia with normal cytogenetics (CN-AML) have diverse outcomes explained, in part, by different mutation topography. DEAD/H-box helicase 11 mutations are associated with the rare genetic disease Warsaw breakage syndrome with increasing evidence of a potential role in oncogenesis. We studied DNA samples from 423 consecutive newly-diagnosed adults with CN-AML by deep targeted regional sequencing (TRS). DDX11 mutations were detected in 29 subjects and were significantly associated with higher cumulative incidence of relapse (CIR) with a Hazard Ratio (HR) = 2.17 (95% Confidence Interval [CI], 1.28, 3.66; P = 0.004) and worse relapse-free survival (RFS; HR = 2.19; [1.29, 3.73]; P = 0.004) compared with subjects with wild-type DDX11 in multi-variable analyses. About two-thirds of the DDX11 mutations were putative germline mutations based on variant allele frequency (VAF) analyses. In 2 subjects we proved germline origin of the DDX11 mutation by analyses of oral mucosa DNA samples from family members. Sub-group analyses suggested germline DDX11 mutations were also significantly associated with higher CIR compared with wild-type DDX11. In conclusion, we show the adverse impact of DDX11 mutations on relapse in persons with CN-AML. The trial is registered at Clinicaltrials.gov (NCT01455272, NCT02185261) and in chictr.org (ChiCTR-OCH-10000940).
Analysis of land suitability for rubber plantations in Sembawa District, Banyuasin Regency, Indonesia
Authors: utomo budi , Septinar Helfa , Putri Mega Kusuma , Ningrum Mei Vita Romadon 
Published: July 2023

Abstract
Rubber cultivation will be productive if it is planted on suitable land. This study analyzes land suitability for rubber plantations in Sembawa District, Banyuasin Regency. The research uses the land suitability evaluation method, with a matching analysis between land characteristics and the requirements for growing rubber plants. The research sample was obtained from the overlay of rainfall maps, slope maps, and soil maps, so six research samples were obtained. The research sample was then analyzed in the laboratory. The analysis results matched the criteria for growing rubber plants, then scored. Interpretation of research results starting from class (S1) is very suitable, class (S2) is moderate suitable, class (S3) is marginally suitable, and class (N) is not suitable. The results showed two categories of land suitability for rubber plantations in Sembawa District: very suitable (S1) and class suitable (S2). Each region has different characteristics, so in maximizing land use, it is necessary to identify the limiting factors for each suitability parameter and management by regional characteristics and improve the limiting factors that can be increased.