bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multiscale integration of human and single-cell variations reveals unadjuvanted vaccine high responders are naturally adjuvanted
Authors: Mulè Matthew P. , Martins Andrew J. , Cheung Foo , Farmer Rohit , Sellers Brian , Quiel Juan A. , Jain Arjun , Kotliarov Yuri , Bansal Neha , Chen Jinguo , Schwartzberg Pamela L. , Tsang John S. 
Published: March 2023

AbstractAdvances in multimodal single cell analysis can empower high-resolution dissection of human vaccination responses. The resulting data capture multiple layers of biological variations, including molecular and cellular states, vaccine formulations, inter- and intra-subject differences, and responses unfolding over time. Transforming such data into biological insight remains a major challenge. Here we present a systematic framework applied to multimodal single cell data obtained before and after influenza vaccination without adjuvants or pandemic H5N1 vaccination with the AS03 adjuvant. Our approach pinpoints responses shared across or unique to specific cell types and identifies adjuvant specific signatures, including pro-survival transcriptional states in B lymphocytes that emerged one day after vaccination. We also reveal that high antibody responders to the unadjuvanted vaccine have a distinct baseline involving a rewired network of cell type specific transcriptional states. Remarkably, the status of certain innate immune cells in this network in high responders of the unadjuvanted vaccine appear “naturally adjuvanted”: they resemble phenotypes induced early in the same cells only by vaccination with AS03. Furthermore, these cell subsets have elevated frequency in the blood at baseline and increased cell-intrinsic phospho-signaling responses after LPS stimulationex vivoin high compared to low responders. Our findings identify how variation in the status of multiple immune cell types at baseline may drive robust differences in innate and adaptive responses to vaccination and thus open new avenues for vaccine development and immune response engineering in humans.
Validity of European-centric derived cardiometabolic polygenic risk scores in multi-ancestry populations
Authors: Topriceanu Constantin-Cristian , Chaturvedi Nish , Mathur Rohini , Garfield Victoria 
Published: March 2023

ABSTRACTPolygenic risk scores (PRSs) provide an individual level estimate of genetic risk for any given disease. Since most PRSs have been derived from genome wide association studies (GWAS) conducted in populations of White European ancestry, their validity in other ancestry groups remains unconfirmed. This is especially relevant for cardiometabolic diseases which are known to disproportionately affect people of non-European ancestry. Thus, we aimed to evaluate the performance of PRSs for glycaemic traits (glycated haemoglobin, type 1, and type 2 diabetes mellitus), cardiometabolic risk factors (body mass index, hypertension, high- and low-density lipoproteins, and total cholesterol and triglycerides) and cardiovascular diseases (CVDs, including stroke and coronary artery disease) in people of White European, South Asian, and African Caribbean ethnicity in the UK Biobank. Whilst the PRSs incorporated some GWAS data from multi-ethnic population, the vast majority originated from White Europeans. Except for hypertension and stroke, PRSs derived mostly from European populations had an overall better performance in White Europeans compared to South Asians and African Caribbeans. Thus, multi-ancestry GWAS data are needed to generate ancestry stratified PRSs to tackle health inequalities.
Characteristics of dynamic assessments of word reading skills and their implications for validity: A systematic review and meta-analysis
Authors: Wood Emily , Biggs Kereisha , Molnar Monika 
Published: March 2023

AbstractDynamic assessments (DAs) of word reading skills demonstrate strong criterion reference validity with word reading measures (WRMs). However, DAs vary in the skills they assess, their format and administration method, and the type of words and symbols used in test items. These characteristics may have implications on assessment validity. To compare validity of DAs of word reading skills on these factors of interest, a systematic search of five databases and the grey literature was conducted. We identified 35 studies that met the inclusion criteria of evaluating participants aged 4-10, using a DA of word reading skills and reporting a Pearson’s correlation coefficient as an effect size. A random effects meta-analysis with robust variance estimation and subgroup analyses by DA characteristics was conducted. There were no significant differences in mean effect size based on administration method (computer vs. in-person) or symbol type (familiar vs. novel). However, DAs that evaluate phonological awareness or decoding (vs. sound-symbol knowledge), those that use a graduated prompt format (vs. test-teach-retest), and DAs that use nonwords (vs. real words) demonstrated significantly stronger correlations with WRMs. These results inform selection of DAs in clinical and research settings, and development of novel, valid DAs of word reading skills.
Psychometric analysis of Integrated Digital Library User Success (IDLUS) Scale in academic digital library environment
Authors: Iqbal Memoona , Rafiq Muhammad 
Published: March 2023

Purpose
The purpose of this study is to execute the application of confirmatory factor analysis in structural equation modeling, to investigate the reliability and validity of the proposed integrated digital library user success (IDLUS) scale in academic digital library computing information system in the area of information management and systems.

Design/methodology/approach
The study analyzed 355 valid responses (MPhil and PhD) from the largest and oldest public sector university in Pakistan. Sample selection was calculated through a stratified random sampling technique from the four faculties of the University of the Punjab. The instrument was constructed based on the available two digital library and information system success models. The first model is Jung’s (1997) digital library user success model that is further composed of flow model (1977), end user computing satisfaction model (1987) and Joshi’s overall user satisfaction model (1990). Similarly, the second model is DeLone and McLean’s reformulated information system success (2003) theory. The question items used a five-point Likert scale and executed regression weights, standardized regression weights, convergent validity, variance extracted, construct reliability and discriminant validity to infer results.

Findings
Findings show that the IDLUS scale has excellent validity and reliability estimates.

Research limitations/implications
The study has theoretical implications for researchers and practical implications for information system developers.

Originality/value
To the best of the authors’ knowledge, this scale is the first-ever effort to measure the digital library user success in the context of Higher Education Commission-National Digital Library of Pakistan. Therefore, there was a dire need to conduct the psychometric analysis of the scale to examine the model fit statistics on the current sample in the particular cultural norms. Scale is based upon human factors taken from various Web success and information system success models from the fields of human–computer interaction information systems and computer-mediated communication.
Micro-credentials and the role of evidence: increasing the potential for learner-centeredness, inclusivity and an expansive model of assessment and credentialing
Authors: Reed Anne 
Published: March 2023

PurposeThis paper examines the innovative potential of micro-credentials which, arguably, is compromised if not for a particular attribute of the digital format: evidence. Evidence allows for an artifact of learning (e.g. project, writing sample) to be included in a digital micro-credential. Micro-credentials that include evidence can support individualized learning; elucidate learners' qualifications; and make assessment and credentialing processes more inclusive.Design/methodology/approachThis conceptual paper explores the subject of higher education micro-credentials which are increasingly being offered as formal (albeit smaller and digital), credit-bearing credentials, far removed from the Open Digital Badge movement from which they originated. This paper presents a case for safeguarding the qualities of micro-credentials that allow for innovative practice, before micro-credentials become entirely subsumed into conventional assessment and credentialing practices.FindingsA review of the literature indicates that evidence, when used effectively, can support the innovative potential of micro-credentials. This subject is examined from the perspective of three categories of evidence, which are identified and illustrated through specific examples from the literature.Originality/valueThis paper fulfills a need to address the features of micro-credentials that, if used effectively, can challenge traditional assessment and credentialing paradigms. Evidence is rarely discussed in the literature and has not been thoroughly examined from this perspective. Additionally, faculty who develop and implement micro-credentials face numerous challenges when attempting to include evidence in micro-credentials. This paper explores those challenges and offers several recommendations for practice.
The impact of cultural dimensions on project management performance
Authors: Battistella Cinzia , Bortolotti Thomas , Boscari Stefania , Nonino Fabio , Palombi Giulia 
Published: March 2023

Purpose
Diverse cultures may make people behave differently and this, in turn, can impact project management. While the relationship between culture and project success has been widely explored, there is a need of addressing the gap in the relationship between culture and project management performance outcomes, that is, the performance in implementing project management processes and practices. The purpose of this paper is to investigate this gap by studying the role of cultural dimensions on project management performance.

Design/methodology/approach
An explorative survey including 200 observations relating to the experiences of project managers with a big experience on projects involving many different national cultures has been conducted to collect primary data on the relationship between the nationality observed and the project management performance outcomes shown. Nationality has been used as a proxy to link individual cultural dimensions and project management performance.

Findings
The results of this paper show that individualism impacts project dynamics and project control positively. Moreover, masculinity impacts project dynamics positively, and uncertainty avoidance impacts project control negatively. When recognized, different cultural dimensions can drive project management performance outcomes. The increasing awareness on this topic can be a valid instrument to control the cultural effect and take advantage of it to enhance project success.

Originality/value
This study contributes to the theory of project management by recognizing linkages between cultural dimensions and project management performance. Moreover, this study overcomes the concept of nationality, focusing on individuals and their unique set of cultural dimensions.
Contagious crowds and rational faithfuls: a club theory approach
Authors: Animashaun Jubril Olayinka 
Published: March 2023

PurposeThis study investigates the observed resurgence in religious beliefs seen across many societies during the COVID-19 pandemic. Using the economic theory of religious clubs, the author models religious participation during the pandemic as a mechanism for alleviating the financial distress associated with the health distress from the pandemic.Design/methodology/approachUsing data from the COVID-19 National Longitudinal Phone Survey (NLPS) in Nigeria, the author investigates the economic motivation for religious intensity during the COVID-19 pandemic. To address endogeneity concerns, the author exploits geographic variables of temperature and longitudes as sources of COVID-19 risk.FindingsOverall, health distress stimulates religious intensity. Consistent with the economic theory of religious clubs, adverse health shocks stimulate financial distress, and the effect is stronger among religious participants. Similarly, people see God and not the government as a source of protection against COVID-19.Research limitations/implicationsThe study’s model sees religious organizations as public goods providers, especially when governments and markets are inefficient.Practical implicationsThe study’s recommendations support an expanded role for religious networks in healthcare delivery and more public funding to attenuate the post-pandemic resurgence of social violence in economically distressed regions.Social implicationsDespite the research interest in the COVID-19 pandemic, the long-term implications, many of which relate to social behavior adjustments that cause individuals to identify more closely with their social group, need greater understanding. Suppose religious intensity is linked to economic distress. In that case, this is a major source of worry for countries whose economies are subject to higher fluctuations and where the governments and markets are inefficiently organized. These regions may be more susceptible to a resurgence in religious fundamentalism associated with the economic shocks from the pandemic. Consequently, these regions would require more public funding to attenuate the potential for costly activities like organized violence, suicide attacks and terrorist activities in the aftermath of the pandemic.Originality/valuePrompted by the observation of the increase in religious identity through religious intensity during the pandemic, the author contributes by developing theoretically-based hypotheses that are incentive-compatible to provide a rational justification for the observation. The author empirically validates the hypothesis by taking advantage of the COVID-19 National Survey in Nigeria by specifically using survey rounds 4 and 7 which have more comprehensive religious items included.Peer reviewThe peer review history for this article is available at:https://publons.com/publon/10.1108/IJSE-11-2022-0719
Efficient operation and maintenance (O&M) framework in managing stratified residential properties
Authors: Che-Ghani Nor Zaimah , Myeda Nik Elyna , Ali Azlan Shah 
Published: March 2023

Purpose
To achieve efficient operation and maintenance (O&M) management, this study seeks to identify critical success factors (CSFs) affecting service delivery factors of O&M services at stratified residential buildings. The purpose of this study is to yield measurable data for developing an effective O&M framework to enhancing its performance. In future research, this study will further investigate the relationship between the CSF and service performance factors.

Design/methodology/approach
This study adopts a combination of qualitative and quantitative techniques that yields conclusive study findings while improving the research’s validity and dependability. Two series of instruments were conducted in an effort to refine the efficient O&M framework variables. Instruments used in addressing the research gap were a questionnaire survey and focus group discussion (FGD). Analysis of data was completed via the Statistical Package for the Social Sciences (SPSS) programme for quantitative data and thematic analysis for qualitative data.

Findings
This study concludes that the CSFs directly affect the performance of O&M. Questionnaire survey and FGD findings have refined the CSF into three main categories, namely, building characteristics, O&M management and community participation. FGD experts further suggested that service performance factors can be measured against SERVQUAL service qualities such as reliability, tangible, responsiveness, assurance and empathy.

Research limitations/implications
Future research may consider the inclusion of financial elements in the O&M service delivery.

Originality/value
This study presents a fresh insight into the CSFs that construct an efficient O&M framework through rigorous steps of data collection and analysis. This study proposes impactful guidance for policymakers, practitioners and residents on the significance of all parties’ involvement to support the management of residential buildings, where the current practice of O&M constantly faces complex issues. This study derives novice strategies that should correspond to the growing issues and challenges in managing residential buildings. The deeper insight into the role of O&M represents a direction for the future development of facilities management progress and stratified residential building sectors.
Digital accounting systems and information technology in the public sector: mutual interaction
Authors: Alsharari Nizar Mohammad , Ikem Fidelis 
Published: March 2023

Purpose
This study aims to explain the mutual interaction between digital accounting systems and information technology in public sector transformation, Jordan Customs.

Design/methodology/approach
This paper adopts an interpretive case study approach. This study uses the triangulation method of data collection, including interviews, observations, documents and archival records. It responds to the recent call by Myers and Newman (2007, p. 1) as “The qualitative interview is one of the most important data gathering tools in qualitative research, yet it has remained an unexamined craft in IS research.”

Findings
This paper concludes that the digital accounting systems and information technology are inextricably linked; each leads to the other. The interaction process between digital accounting systems and information technology helps identify and recognize the dynamics that have been manifested between them. The relationships between the information technology and digital accounting dynamics at the inherent organizational and accounting levels are both recursive and have two-way, with the two concepts inextricably interwoven.

Research limitations/implications
The specificity of location and organization type in the case study impede the generalization of the findings. Digital accounting systems bind organizations to fundamental choices about how their accounting activities should be organized as unquestioned choices. This paper thus has important implications for academics and practitioners on accounting systems and information technology in responding to recent calls to bridge the gap between the extra- and intraorganizational levels of analysis.

Originality/value
The originality of this research is that dealing with digital government development and accounting systems and rules does not limit one to tackling only technical issues. These two pivotal digitalization and accounting reforms can lead to accounting changes and new organizational approaches, thus affecting public organizations’ economic and political lives. To the best of the authors’ knowledge, this paper is one of the few case studies in the information technology and accounting literature to analyze organizations’ digitalization issues when changing their way of doing as influenced by information technology.
Grain size responsive uniaxial tensile behavior of polycrystalline nanocopper under different temperatures and strain rates
Authors: Kumar Rajat , Gupta Mahesh Kumar , Rai Santosh Kumar , Panwar Vinay 
Published: March 2023

PurposeThe changes in tensile behavior of polycrystalline nanocopper lattice with changes in temperature, average grain size (AGS) and strain rate, have been explored. The existence of a critical AGS has also been observed which shows that the Hall–Petch relationship behaves inversely.Design/methodology/approachNanoscale deformation of polycrystalline nanocopper has been done in this study with the help of an embedded atom method (EAM) potential. Voronoi construction method has been employed for creating four polycrystals of nanocopper with different sizes. Statistical analysis has been used to examine the observations with emphasis on the polycrystal size effect on melting point temperature.FindingsThe study has found that the key stress values (i.e. elastic modulus, yield stress and ultimate tensile stress) are significantly influenced by the considered parameters. The increase in strain rate is observed to have an increasing impact on mechanical properties, whereas the increase in temperature degrades the mechanical properties. In-depth analysis of the deformation mechanism has been studied to deliver real-time visualization of grain boundary motion.Originality/valueThis study provides the relationship between required grain size variations for consecutive possible variations in mechanical properties and may help to reduce the trial processes in the synthesis of polycrystalline copper based on different temperatures and strain rates.
Experimental investigations into additive manufacturing of styrene-ethylene-butylene-styrene block copolymers using solvent cast 3D printing technique
Authors: Kumar Arun , Pandey Pulak Mohan , Jha Sunil , Banerjee Shib Shankar 
Published: March 2023

Purpose
This paper aims to discuss the successful 3D printing of styrene–ethylene–butylene–styrene (SEBS) block copolymers using solvent-cast 3D printing (SC-3DP) technique.

Design/methodology/approach
Three different Kraton grade SEBS block copolymers were used to prepare viscous polymer solutions (ink) in three different solvents, namely, toluene, cyclopentane and tetrahydrofuran. Hansen solubility parameters (HSPs) were taken into account to understand the solvent–polymer interactions. Ultraviolet–visible spectroscopy was used to analyze transmittance behavior of different inks. Printability of ink samples was compared in terms of shape retention capability, solvent evaporation and shear viscosity. Dimensional deviations in 3D-printed parts were evaluated in terms of percentage shrinkage. Surface morphology of 3D-printed parts was investigated by scanning electron microscope. In addition, mechanical properties and rheology of the SC-3D-printed SEBS samples were also investigated.

Findings
HSP analysis revealed toluene to be the most suitable solvent for SC-3DP. Cyclopentane showed a strong preferential solubility toward the ethylene–butylene block. Microscopic surface cracks were present on tetrahydrofuran ink-based 3D-printed samples. SC-3D-printed samples exhibited high elongation at break (up to 2,200%) and low tension set (up to 9%).

Practical implications
SC-3DP proves to be an effective fabrication route for complex SEBS parts overcoming the challenges associated with fused deposition modeling.

Originality/value
To the best of authors’ knowledge, this is the first report investigating the effect of different solvents on physicomechanical properties of SC-3D-printed SEBS block copolymer samples.