bluuebunny/crossref_metadata_2025_split huggingface dataset:
Striking the right balance: understanding the strategic applications of hydrogen in transitioning to a net zero emissions economy
Authors: Whitehead Jake , Newman Peter , Whitehead Jessica , Lim Kai Li 
Published: January 2023

AbstractThe hydrogen economy has been a major vision for many futurists, for over half a century, as a way to transition to a world not dependent on fossil fuels (Bockris, Science 176:1323, 1972). As with many world views, the hydrogen economy has a complete perspective from which all potential change can be viewed. It therefore has a passionate if somewhat fundamentalist following. This paper outlines how electrification has now superseded much of the originally envisaged hydrogen economy and thus it deconstructs what is left of this vision to highlight hydrogen’s strategic, niche, yet important roles, that remain for supporting the transition to a global net zero emissions economy. In our view, it is critical that policy-makers, industry and researchers take a strategic view on striking the right balance on the adoption of hydrogen. Here we propose a framework for hydrogen development globally, with support directed towards enabling the decarbonisation of harder-to-electrify sectors using renewable hydrogen, including, but not limited to: steel, cement, fertilisers, chemical feedstocks, shipping, and aviation.
Value of 18F-FDG PET/CT in guiding management of facet joint arthropathy
Authors: Houseni Mohamed , Bural Gonca , Elnaggar Mohamed Ahmed , Omar Hazem 
Published: January 2023

Abstract
Background
Facet joint arthropathy is one of the causes of back and neck pain. Diagnosing facet arthropathy as the source of pain is a medical challenge. The purpose of this study was to investigate the potential role of 18F-FDG PET/CT imaging to precisely target the active inflammatory facet joints.

Methods
A prospective study included 129 patients with chronic neck or back pain and no neurologic or radiologic findings to diagnose intervertebral-disk-related pain. 18F-FDG PET/CT imaging was performed to evaluate the cause of pain. None of the patients had any malignant or traumatic lesions in the spine. The PET findings were compared to the CT findings. In addition, the PET/CT findings were correlated with the clinical findings.

Results
The images of PET/CT of 54 patients demonstrate abnormally increased FDG uptake in facet joints. Thirty patients had bilateral abnormally increased FDG uptake in facet joints (24 lumbar, 6 cervical facet joints). Of these 30 patients, 12 had a normal appearance of facet joints on CT, 12 had mild degenerative changes limited to the affected facet joints, and 6 had moderate multilevel degenerative changes affecting the facet joints on CT. Twenty-four patients had unilateral increased FDG uptake at facet joints (6 lumbar, 18 cervical facet joints). Among these 24 patients with unilateral increased FDG uptake at facet joints, 12 had a normal facet joints appearance on CT, while the other 12 had marked multilevel degenerative changes affecting the facet joints. The positive findings of PET or CT have been correlated with the neurological examination and injection therapy outcome.

Conclusions
18F-PET/CT has incremental value in the management of pain resulting from facet arthropathy by targeting the affected joints, especially when conventional imaging findings are non-specific or show no abnormality. The most effective management for facet arthropathy is nerve root block; therefore, PET/CT may outline and guide the management to target the active inflammatory facet joints.
Utrecht Gender Dysphoria Scale – Gender Spectrum in a Chinese population: scale validation and associations with mental health, self-harm and suicidality
Authors: Chen Runsen , Feng Yi , Su Di , Wilson Amanda , Han Meng , Wang Yuanyuan 
Published: January 2023

Background
Individuals with gender dysphoria display an incongruence between birth-assigned gender and gender expression. However, there is no existing Chinese measure for gender dysphoria.

Aims
This study aims to validate the Utrecht Gender Dysphoria Scale – Gender Spectrum (UGDS-GS) in a Chinese population, and compare the psychometric properties of the UGDS-GS with one frequently used scale for gender dysphoria measurement, the Gender Identity/Gender Dysphoria Questionnaire for Adolescents and Adults (GIDYQ-AA).

Method
A total of 2646 Chinese participants were recruited. The following information was collected: sociodemographic variables, gender identity, sexual orientation, gender dysphoria measured by the UGDS-GS and the GIDYQ-AA, anxiety, depression and suicide assessment. Principal component analyses and confirmatory factor analysis (CFA) were conducted to test the fitness of the model. Discriminant validity was tested with one-way analysis of variance.

Results
The UGDS-GS showed good psychometric properties, with the GIDYQ-AA demonstrating slightly better psychometric properties than the UGDS-GS. UGDS-GS also showed strong internal consistency (Cronbach's α = 0.89), and good convergent validity and criterion validity. Exploratory factor analysis showed a one-factor structure (Kaiser-Meyer-Olkin test, 0.93; χ2 = 13 342.50; d.f. = 153; P < 0.001). The UGDS-GS was positively associated with anxiety symptoms, depressive symptoms, suicidal ideation, attempted suicide and self-harm. We also found the results were robust in different samples.

Conclusions
The validated UGDS-GS can significantly stimulate and promote gender dysphoria assessment in Chinese populations, allowing for assessment in a more diverse subset of gender minorities.
HLA Class I Association With Autoimmune Diabetes in Chinese People: Distinct Implications in Classic Type 1 Diabetes and LADA
Authors: Xia Ying , Chen Yan , Li Xia , Luo Shuoming , Lin Jian , Huang Gan , Xiao Yang , Chen Zhiying , Xie Zhiguo , Zhou Zhiguang 
Published: January 2023

Abstract

Context
We aimed to investigate whether human leukocyte antigen (HLA) Class I loci differentially modulated the risk for and clinical features of Chinese people with classic type 1 diabetes (T1D) and latent autoimmune diabetes in adults (LADA).

Methods
In this case–control study, genotypes of HLA-A, -B, -C, -DRB1, -DQA1, and -DQB1 loci were obtained from 1067 cases with classic T1D, 1062 cases with LADA, and 1107 normal controls using next-generation sequencing.

Results
Despite 4 alleles shared between classic T1D and LADA (protective: A*02:07 and B*46:01; susceptible: B*54:01 and C*08:01), 7 Class I alleles conferred risk exclusively for classic T1D (A*24:02, B*15:02, B*15:18, B*39:01, B*40:06, B*48:01, and C*07:02) whereas only A*02:01 was an additional risk factor for LADA. Class I alleles affected a wide spectrum of T1D clinical features, including positive rate of protein tyrosine phosphatase autoantibody and zinc transporter 8 autoantibody (A*24:02), C-peptide levels (A*24:02), and age at diagnosis (B*46:01, C*01:02, B*15:02, C*07:02, and C*08:01). By contrast, except for the detrimental effect of C*08:01 on C-peptide concentrations in LADA, no other Class I associations with clinical characteristics of LADA could be reported. The addition of Class I alleles refined the risk model consisting only of DR-DQ data in classic T1D while the overall predictive value of the LADA risk model comprising both Class I and II information was relatively low.

Conclusion
The attenuated HLA Class I susceptibility to LADA was indicative of a less deleterious immunogenetic nature compared with classic T1D. These autoimmune diabetes–related Class I variants might serve as additional markers in future screening among Chinese people.
iTRAQ-based Proteomic Analysis Unveils ACSL4 as a Novel Potential Regulator of Human Endometrial Receptivity
Authors: Hu Shuanggang , Sun Zhe , Li Boyu , Zhao Hanting , Wang Yuan , Yao Guangxin , Li Xinyu , Bian Xuejiao , Li Tin Chiu , Vankelecom Hugo , Sun Yun 
Published: January 2023

Abstract
Competent endometrial receptivity is a prerequisite for successful embryo implantation. Identification of novel key molecules involved in endometrial receptivity is essential to better interpret human implantation and improve pregnancy rates in assisted reproduction treatment. Isobaric tags for relative and absolute quantitation (iTRAQ)-based proteomics was performed to profile the proteomes of the prereceptive (luteinizing hormone [LH] + 2, n = 4) and receptive (LH + 7, n = 4) endometrial tissues. A total of 173 differentially expressed proteins (DEPs) between LH + 2 and LH + 7 endometrial samples were identified. Integrated analysis of the proteomic data and published transcriptomic data was performed to identify the concordant DEPs with differential expression at both the messenger RNA and protein levels. Protein-protein interaction (PPI) network analysis was performed on concordant DEPs. We first identified 63 novel concordant DEPs and 5 hub proteins (ACSL4, ACSL5, COL1A1, PTGS1, and PLA2G4F) between LH + 2 and LH + 7 endometrial samples. ACSL4 was predominantly expressed in endometrial epithelial cells and its expression was significantly upregulated by progesterone in the LH + 7 endometrium and significantly downregulated in repeated implantation failure patients. Knockdown of ACSL4 in endometrial epithelial cells induced the downregulation of endometrial receptivity markers (HOXA10, COX2, and LIF) and the significant decrease of implantation rate during in vitro implantation analysis. This study provides the first gel-independent quantitative proteomes of the LH + 2 and LH + 7 human endometrium using iTRAQ technology. The identified concordant DEPs and hub proteins open a new avenue for future studies aimed at elucidating the underlying mechanisms governing endometrial receptivity. ACSL4 was identified as a novel regulatory molecule in the establishment of endometrial receptivity and might play important roles during implantation.
Fashions and Wars
Authors: Banerjee Ria 
Published: January 2023

Abstract
Most accounts of E. M. Forster recall him as a dowdy man in a suit, someone Lytton Strachey nicknamed “the Taupe” for his restricted sartorial palette. The ability to wear unfashionable clothes without causing remark is an exercise of privilege that Forster became aware of during his time working for the Red Cross (1916–19), and through interactions with his Egyptian friend, Mohamed El-Adl. Refusing to wear his uniform after work, Forster broke away from convention to wear one of the three suits he had brought with him to Egypt even as he embarked on a difficult love affair with El-Adl. Their clothes-based interactions prompted Forster to question and discard many of his colonialist biases. The suit, previously an unexamined everyday object, thus becomes a loaded metaphor for social privilege and unwilling complicity with national politics in Forster’s essay “Me, Them and You” (1925). The sartorial symbols that emerge from his letters, essays, and the archive he created of El-Adl’s notes allow us to reapproach the philosophical idea with which he is most closely associated: liberal humanism. This essay finally suggests that Forster’s experiences in Egypt led to an intersectional humanist position that holds interest for global modernist approaches.
Fashion in Așǫs
Authors: Okasaki Aymê 
Published: January 2023

Abstract
This article discusses the concept of Afro-Brazilian fashion in Candomblé, considering their transatlantic symbolic exchanges in an aesthetics of dress, based on the four vectors proposed by Cunnington—fabric, color, shape, and mobility—through which fashion is expressed. In the eighteenth and nineteenth centuries, Brazil received ships from the African coast with așǫ oke, a handwoven fabric created by the Yorùbás to be used as head wraps or to be sewn and worn as shawls by Black women. This and other fabrics, such as wax prints, enter the terreiros as a search for aesthetic identity through clothing, especially during the second half of the twentieth century with the (re)Africanization movement. In this scenario, fabric and color join the shapes and silhouettes of Candomblé costumes to create aesthetic crossovers. While silhouettes common to Brazil’s colonial period meet the various forms of fabric binding in traditional Candomblé costumes, the (re)Africanized terreiros bring more rectangular shapes to their dress. Adorning these costumes are the insignias worn by the òrìṣàs, which act as an extension of their gestures. Wielding, wearing, and adorning themselves with different insignias on their arms, head, and legs, the òrìṣàs dramatize their mythical stories, in narrative and symbolic performances of dress. Thus the Afro-Atlantic fashion seen in these costumes escapes the boundaries of Euro-Western fashion.
Lagerfeld, Fashion, and Cultural Heritage
Authors: Garelick Rhonda 
Published: January 2023

Abstract
When Karl Lagerfeld took over the Maison Chanel in 1983, its founder, Coco Chanel, had been dead for twelve years, and the iconic brand was foundering. Once the epitome of French glamour, history, and feminine luxury, the house was rapidly losing prestige and relevance. Lagerfeld revived the brand through a complex reinterpretation of its iconography, its founder’s persona, and especially its relationship to French identity and patrimoine culturel—cultural patrimony. His reign at Chanel amounted to a de facto commentary on nationality, personality, style, and gender, demonstrating how history and politics get filtered and expressed through fashion.
Impact of the COVID-19 pandemic on the incidence and clinical outcomes of diabetic ketoacidosis among male and female children with type 1 diabetes: systematic review and meta-analysis
Authors: Meregildo-Rodriguez Edinson Dante , León-Jiménez Franco Ernesto , Tafur-Hoyos Brenda Aurora Dolores , Vásquez-Tirado Gustavo Adolfo 
Published: January 2023

Background: Some studies suggest that the SARS-CoV-2 pandemic increased the incidence of type 1 diabetes mellitus (T1DM) and diabetic ketoacidosis (DKA). However, the impact of this pandemic on pediatric T1DM is still mostly unknown. Therefore, we aimed to assess the effect of the COVID-19 pandemic on clinical outcomes in children with T1DM. Methods: We systematically searched for six databases up to 31 August 2022. We included 46 observational studies, 159,505 children of both sexes with T1DM, and 17,547 DKA events. Results: The COVID-19 pandemic significantly increased, in both sexes, the incidence of 1) DKA (OR 1.68; 95% CI 1.44–1.96), 2) severe DKA (OR 1.84; 95% CI 1.59–2.12), 3) DKA in newly diagnosed T1DM (OR 1.75; 95% CI 1.51–2.03), and 4) ICU admissions (OR 1.90; 95% CI 1.60–2.26). However, we did not find a significant association between this pandemic and 1) the incidence of T1DM, 2) the incidence of DKA in established T1DM, 3) the incidence of KDA complications, 4) the length of hospitalization stay, and 5) mortality. Subgroup analysis showed that the study design and the continent of origin accounted for the heterogeneity. Conclusions: The pandemic SARS-CoV-2 raised, in both sexes, the risk of DKA, severe DKA, DKA de novo, and ICU admissions.
Anatomical variations of frontal sinus pneumatization: A computed tomography-based study
Authors: Al Hatmi Asma Sulaiman , Al Ajmi Eiman , Albalushi Halima , Al Lawati Meetham , Sirasanagandla Srinivasa Rao 
Published: January 2023

Background: The pneumatization of the frontal sinus is variable between individuals, including monozygotic twins. The volumetric anatomic variants of the frontal sinus are classified into aplasia, hypoplasia, medium-sized, and hyperplasia. We aimed to study the frontal sinus morphology in Omani patients using computed tomography (CT) evaluations. Methods: Retrospectively, 1220 paranasal sinus CT scans from 610 patients investigated at Sultan Qaboos University Hospital, Oman, from January 2019 to December 2020 were reviewed. The frontal sinus morphology was classified according to the classification proposed by Guerram et al. The Chi-square test was used to determine the influence of sex. Results: With regard to the unilateral occurrence, the most prevalent frontal sinus category observed was medium-sized (13.3%), followed by hyperplasia (7.9%), hypoplasia (5.4%), and aplasia (2%) categories. Similarly, in bilateral occurrence, the most common frontal sinus category observed was medium-sized (53%), followed by hyperplasia (13.1%), hypoplasia (3.4%) and aplasia (2%) categories. Right and left frontal sinus aplasia were observed in 2.1% and 1.8% of cases, respectively. In terms of sex influence, the left unilateral (p<0.01) and the bilateral hypoplasia (p<0.05) were significantly higher in females. On the other hand, the left unilateral (p<0.01) and the bilateral hyperplasia (p<0.05) were higher in males. Conclusions: The baseline data of frontal sinus category frequencies reported in the present study is helpful in the diagnostic evaluation of sinusitis in the clinical setting. The preoperative recognition of frontal sinus types, particularly frontal sinus aplasia in multiplanar CT scans, is crucial to avoid unexpected complications while performing endoscopic sinus surgery.
Anti-Black racism in clinical supervision: asynchronous simulated encounters facilitate reflective practice
Authors: Calhoun Amanda J. , Martin Andrés , Adigun Ayodola , Alleyne Shirley D. , Aneni Kammarauche , Thompson-Felix Tara , Asnes Andrea , de Carvalho-Filho Marco A. , Benoit Laelia , Genao Inginia 
Published: January 2023

Background Racist interactions in clinical practice remain a pervasive reality for Black healthcare providers. We sought to develop a framework to inform supervisors’ actions when confronting racism in clinical practice and protecting trainees under their oversight. Methods We conducted a prospective study in which experienced supervisors responded to seven short, videotaped interactions between: 1) Black trainees and a simulated patient (SP) in a racist role; 2) the trainees and their respective supervisors; and 3) the trainees and their supervisors together with the SP. The clinical exchanges exemplified different types of racist (entrenching) or antiracist (uprooting) behaviors by the supervisors. After viewing each clip, participants wrote their reflections confidentially; they later joined a structured debriefing together. We used thematic analysis to identify supervisors’ behavioral patterns when confronting racist interactions. Results Based on the input of 52 participants recruited into five two-hour-long sessions, we categorized the behaviors of supervisors facing anti-Black racial injuries involving learners under their oversight. We organized supervisor behaviors into five interlocking domains, each with a range of possible themes: 1) Joining: from conciliatory to confrontational in communicating with the aggressor; 2) Explicitness: from avoiding to naming racism; 3) Ownership: from individual to shared responsibility of the event and the response to it; 4) Involving: from excusing to including the aggrieved party when confronting the aggressor; and 5) Stance: from protective to paternalistic in supporting the learner’s autonomy. Conclusions Our qualitative findings can provide a framework for facilitated discussion toward reflective practice among healthcare providers who may have experienced, witnessed, or intervened in anti-Black racist interactions. They can also help medical educators to inform faculty development to fight anti-Black racism in clinical practice. The video materials we developed are available for viewing and download and can be used or adapted as springboards for reflective discussion or faculty development activities.
Ego depletion and implicit and explicit determinants of condom use intentions: an experimental study among young men
Authors: Wolfs Kenny , Bos Arjan E.R. , Mevissen Fraukje E.F. , Alberts Hugo , van Lankveld Jacques J.D.M. 
Published: January 2023

Background: The Reflective Impulsive Model of Strack and Deutsch (2004) is a dual-process model and could be a dynamic theoretical framework of sexual risk behavior that is able to predict condom use under different circumstances. If we apply the Reflective Impulsive Model to sexual risk behavior, implicit attitudes regarding sexual risk behavior should have a stronger impact on behavior when working memory capacity is low. Explicit attitudes have a strong impact on intentions, which diminishes as participants have less working memory capacity. Methods: In this study, we induced a state of ego depletion to examine the impact of low working memory capacity on implicit and explicit attitudes and condom use intentions. Young, male participants (N = 66) were randomly assigned to either an ego depletion condition (difficult calculus task) or a placebo condition (easy calculus task). At baseline, a questionnaire measuring explicit attitudes and intentions to use a condom, and an Implicit Association Test measuring implicit attitudes towards condoms were administered. After the ego calculus task, participants once more completed the questionnaire and Implicit Association Test. Results: We found no evidence that ego depletion had an effect on intentions to use a condom in young men. Explicit attitudes predicted intentions to use a condom, regardless of participants’ state. We found no relationship between implicit condom attitudes and intentions to use a condom, neither in the ego depletion nor in the placebo condition. Conclusions: The implications of this null finding are discussed.
Risk factor-based screening compared to universal screening for gestational diabetes mellitus in marginalized Burman and Karen populations on the Thailand-Myanmar border: An observational cohort
Authors: Prüst Janna T. , Brummaier Tobias , Wah Mu , Yee Htay Htay , Win Nyo Nyo , Pimanpanarak Mupawjay , Min Aung Myat , Gilder Mary Ellen , Tun Nay Win , Ilozumba Onaedo , Kabeer Basirudeen Syed Ahamed , Terranegra Annalisa , Nosten Francois , Lee Sue J. , McGready Rose 
Published: January 2023

Background: Gestational diabetes mellitus (GDM) contributes to maternal and neonatal morbidity. As data from marginalized populations remains scarce, this study compares risk-factor-based to universal GDM screening in a low resource setting. Methods: This is a secondary analysis of data from a prospective preterm birth cohort. Pregnant women were enrolled in the first trimester and completed a 75g oral glucose tolerance test (OGTT) at 24-32 weeks' gestation. To define GDM cases, Hyperglycaemia and Adverse Pregnancy Outcomes (HAPO trial) criteria were used. All GDM positive cases were treated. Sensitivity and specificity of risk-factor-based selection for screening (criteria: age ≥30y, obesity (Body mass index (BMI) ≥27.5kg/m2), previous GDM, 1st degree relative with diabetes, previous macrosomia (≥4kg), previous stillbirth, or symphysis-fundal height ≥90th percentile) was compared to universal screening using the OGTT as the gold standard. Adverse maternal and neonatal outcomes were compared by GDM status. Results: GDM prevalence was 13.4% (50/374) (95% CI: 10.3-17.2). Three quarters of women had at least one risk factor (n=271 women), with 37/50 OGTT positive cases correctly identified: sensitivity 74.0% (59.7-85.4) and specificity 27.8% (3.0-33.0). Burman women (self-identified) accounted for 29.1% of the cohort population, but 38.0% of GDM cases. Percentiles for birthweight (p=0.004), head circumference (p=0.002), and weight-length ratio (p=0.030) were higher in newborns of GDM positive compared with non-GDM mothers. 21.7% (75/346) of newborns in the cohort were small-for-gestational age (≤10th percentile). In Burman women, overweight/obese BMI was associated with a significantly increased adjusted odds ratio 5.03 (95% CI: 1.43-17.64) for GDM compared with normal weight, whereas in Karen women, the trend in association was similar but not significant (OR 2.36; 95% CI 0.95-5.89). Conclusions: Risk-factor-based screening missed one in four GDM positive women. Considering the benefits of early detection of GDM and the limited additional cost of universal screening, a two-step screening program was implemented.