bluuebunny/crossref_metadata_2025_split huggingface dataset:
Experimental scatter of the fatigue response of additively manufactured components: a statistical method based on the Profile Likelihood
Authors: Tridello A. , Boursier Niutta C. , Rossetto M. , Berto F. , Paolino D. S. 
Published: September 2023

AbstractThe fatigue response of additively manufactured (AM) specimens is mainly driven by manufacturing defects, like pores and lack of fusion defects, which are mainly responsible for the large variability of fatigue data in the S–N plot. The analysis of the results of AM tests can be therefore complex: for example, the influence of a specific factor, e.g. the building direction, can be concealed by the experimental variability. Accordingly, appropriate statistical methodologies should be employed to safely and properly analyze the results of fatigue tests on AM specimens. In the present paper, a statistical methodology for the analysis of the AM fatigue test results is proposed. The approach is based on shifting the experimental failures to a reference number of cycles starting from the estimated P–S–N curves. The experimental variability of the fatigue strength at the reference number of cycles is also considered by estimating the profile likelihood function. This methodology has been validated with literature datasets and has proven its effectiveness in dealing with the experimental scatter typical of AM fatigue test results.
Detection and attribution of intra-annual mass component of sea-level variations along the Norwegian coast
Authors: Mangini Fabio , Bonaduce Antonio , Chafik Léon , Raj Roshin , Bertino Laurent 
Published: September 2023

AbstractReliable sea-level observations in coastal regions are needed to assess the impact of sea level on coastal communities and ecosystems. This paper evaluates the ability of in-situ and remote sensing instruments to monitor and help explain the mass component of sea level along the coast of Norway. The general agreement between three different GRACE/GRACE-FO mascon solutions and a combination of satellite altimetry and hydrography gives us confidence to explore the mass component of sea level in coastal areas on intra-annual timescales. At first, the estimates reveal a large spatial-scale coherence of the sea-level mass component on the shelf, which agrees with Ekman theory. Then, they suggest a link between the mass component of sea level and the along-slope wind stress integrated along the eastern boundary of the North Atlantic, which agrees with the theory of poleward propagating coastal trapped waves. These results highlight the potential of the sea-level mass component from GRACE and GRACE-FO, satellite altimetry and the hydrographic stations over the Norwegian shelf. Moreover, they indicate that GRACE and GRACE-FO can be used to monitor and understand the intra-annual variability of the mass component of sea level in the coastal ocean, especially where in-situ measurements are sparse or absent.
Fluoride distribution in selected foodstuffs from Nakuru County, Kenya, and the risk factors for its human overexposure
Authors: Nelima Delphine , Wambu Enos W. , Kituyi John L. 
Published: September 2023

AbstractCritical data on the impacts of fluoride (F) in food systems along the Eastern Africa Rift Valley System (EARS) is needed for public health risk assessment and for the development of strategies for ameliorating its deleterious effects among the affected communities. Long-term F overexposure causes dental and skeletal fluorosis, and leads to neurotoxicity, which impacts several important body functions. Investigating F exposure pathways is of essence to inform and safeguard public health of the affected communities. The current study assessed the F levels in potatoes (Solanum tuberosum L.), beans (Phaseolus vulgaris L.) and garden peas (Possum sativa) from Nakuru County, Kenya, by potentiometric analysis using F ion-selective electrodes. It then evaluated the risk factors for excessive human exposure to F through contaminated foodstuffs. The mean F levels in the potatoes (8.50 ± 4.70 mg/kg), beans (8.02 ± 4.12 mg/kg) and peas (4.99 ± 1.25 mg/kg) exceeded recommended dietary allowances (RDA) level of 4 mg/kg endorsed by US Institute of Medicine for the different categories of people. The F distribution trends in beans and potatoes reflected the environmental patterns of F contamination of the study area but the spatial extent Fin the peas indicated existence of partial resistance of the pea plants to environmental F uptake. The results indicated that both the beans and the potatoes were more liable to accumulating greater amounts of F from the environment than garden peas and that all the three foodstuffs contained high F levels that posed greater risk of F overexposure and its deleterious impacts among the young children, male populations, and in people of greater body weight and high physical activity levels.
Novel insights for a nonlinear deterministic-stochastic class of fractional-order Lassa fever model with varying kernels
Authors: Rashid Saima , Karim Shazia , Akgül Ali , Bariq Abdul , Elagan S. K. 
Published: September 2023

AbstractLassa fever is a hemorrhagic virus infection that is usually spread by rodents. It is a fatal infection that is prevalent in certain West African countries. We created an analytical deterministic-stochastic framework for the epidemics of Lassa fever employing a collection of ordinary differential equations with nonlinear solutions to identify the influence of propagation processes on infected development in individuals and rodents, which include channels that are commonly overlooked, such as ecological emergent and aerosol pathways. The findings shed light on the role of both immediate and subsequent infectiousness via the power law, exponential decay and generalized Mittag-Leffler kernels. The scenario involves the presence of a steady state and an endemic equilibrium regardless of the fundamental reproduction number, $$\Re _{0}<1$$

ℜ
0

<
1

, making Lassa fever influence challenging and dependent on the severity of the initial sub-populations. Meanwhile, we demonstrate that the stochastic structure has an exclusive global positive solution via a positive starting point. The stochastic Lyapunov candidate approach is subsequently employed to determine sufficient requirements for the existence and uniqueness of an ergodic stationary distribution of non-negative stochastic simulation approaches. We acquire the particular configuration of the random perturbation associated with the model’s equilibrium $$\Re _{0}^{s}<1$$

ℜ

0

s

<
1

according to identical environments as the presence of a stationary distribution. Ultimately, modeling techniques are used to verify the mathematical conclusions. Our fractional and stochastic findings exhibit that when all modes of transmission are included, the impact of Lassa fever disease increases. The majority of single dissemination pathways are less detrimental with fractional findings; however, when combined with additional spread pathways, they boost the Lassa fever stress.
Recombinant expression and subcellular targeting of the particulate methane monooxygenase (pMMO) protein components in plants
Authors: Spatola Rossi Tatiana , Tolmie A. Frances , Nichol Tim , Pain Charlotte , Harrison Patrick , Smith Thomas J. , Fricker Mark , Kriechbaumer Verena 
Published: September 2023

AbstractMethane is a potent greenhouse gas, which has contributed to approximately a fifth of global warming since pre-industrial times. The agricultural sector produces significant methane emissions, especially from livestock, waste management and rice cultivation. Rice fields alone generate around 9% of total anthropogenic emissions. Methane is produced in waterlogged paddy fields by methanogenic archaea, and transported to the atmosphere through the aerenchyma tissue of rice plants. Thus, bioengineering rice with catalysts to detoxify methane en route could contribute to an efficient emission mitigation strategy. Particulate methane monooxygenase (pMMO) is the predominant methane catalyst found in nature, and is an enzyme complex expressed by methanotrophic bacteria. Recombinant expression of pMMO has been challenging, potentially due to its membrane localization, multimeric structure, and polycistronic operon. Here we show the first steps towards the engineering of plants for methane detoxification with the three pMMO subunits expressed in the model systems tobacco and Arabidopsis. Membrane topology and protein–protein interactions were consistent with correct folding and assembly of the pMMO subunits on the plant ER. Moreover, a synthetic self-cleaving polypeptide resulted in simultaneous expression of all three subunits, although low expression levels precluded more detailed structural investigation. The work presents plant cells as a novel heterologous system for pMMO allowing for protein expression and modification.
The stability analysis of a nonlinear mathematical model for typhoid fever disease
Authors: Khan Ihsan Ullah , Mustafa Shahbaz , Shokri Ali , Li Shuo , Akgül Ali , Bariq Abdul 
Published: September 2023

AbstractTyphoid fever is a contagious disease that is generally caused by bacteria known as Salmonella typhi. This disease spreads through manure contamination of food or water and infects unprotected people. In this work, our focus is to numerically examine the dynamical behavior of a typhoid fever nonlinear mathematical model. To achieve our objective, we utilize a conditionally stable Runge–Kutta scheme of order 4 (RK-4) and an unconditionally stable non-standard finite difference (NSFD) scheme to better understand the dynamical behavior of the continuous model. The primary advantage of using the NSFD scheme to solve differential equations is its capacity to discretize the continuous model while upholding crucial dynamical properties like the solutions convergence to equilibria and its positivity for all finite step sizes. Additionally, the NSFD scheme does not only address the deficiencies of the RK-4 scheme, but also provides results that are consistent with the continuous system's solutions. Our numerical results demonstrate that RK-4 scheme is dynamically reliable only for lower step size and, consequently cannot exactly retain the important features of the original continuous model. The NSFD scheme, on the other hand, is a strong and efficient method that presents an accurate portrayal of the original model. The purpose of developing the NSFD scheme for differential equations is to make sure that it is dynamically consistent, which means to discretize the continuous model while keeping significant dynamical properties including the convergence of equilibria and positivity of solutions for all step sizes. The numerical simulation also indicates that all the dynamical characteristics of the continuous model are conserved by discrete NSFD scheme. The theoretical and numerical results in the current work can be engaged as a useful tool for tracking the occurrence of typhoid fever disease.
Selective effects of estradiol on human corneal endothelial cells
Authors: Han Seoyoung , Mueller Christian , Wuebbolt Caitlin , Kilcullen Sean , Nayyar Varinda , Calle Gonzalez Brayan , Mahdavi Fard Ali , Floss Jamie C. , Morales Michael J. , Patel Sangita P. 
Published: September 2023

AbstractIn Fuchs endothelial corneal dystrophy (FECD), mitochondrial and oxidative stresses in corneal endothelial cells (HCEnCs) contribute to cell demise and disease progression. FECD is more common in women than men, but the basis for this observation is poorly understood. To understand the sex disparity in FECD prevalence, we studied the effects of the sex hormone 17-β estradiol (E2) on growth, oxidative stress, and metabolism in primary cultures of HCEnCs grown under physiologic ([O2]2.5) and hyperoxic ([O2]A) conditions. We hypothesized that E2 would counter the damage of oxidative stress generated at [O2]A. HCEnCs were treated with or without E2 (10 nM) for 7–10 days under both conditions. Treatment with E2 did not significantly alter HCEnC density, viability, ROS levels, oxidative DNA damage, oxygen consumption rates, or extracellular acidification rates in either condition. E2 disrupted mitochondrial morphology in HCEnCs solely from female donors in the [O2]A condition. ATP levels were significantly higher at [O2]2.5 than at [O2]A in HCEnCs from female donors only, but were not affected by E2. Our findings demonstrate the resilience of HCEnCs against hyperoxic stress. The effects of hyperoxia and E2 on HCEnCs from female donors suggest cell sex-specific mechanisms of toxicity and hormonal influences.
A multiline fitting method for measuring ethylene concentration based on WMS-2f/1f
Authors: Wang W. F. , Yang B. , Liu H. F. , Ren L. F. , He D. , Zhao X. C. , Li J. 
Published: September 2023

AbstractCoal spontaneous combustion risk assessment is a global technical challenge for the sustainable development of deep mining technology, and C2H4 is a key indicator for early warning of coal spontaneous combustion. Tunable diode laser absorption spectroscopy (TDLAS) has the advantages of high selectivity, high sensitivity, high accuracy and real-time on-line measurement, and it can detect multiple gases simultaneously, so it has significant advantages in the accurate detection of coal spontaneous combustion indicator gases. To address the problem of cross-interference between the near-infrared absorption lines of CH4 and C2H4, which are the indicator gases of spontaneous combustion in coal, a multi-line fitting method was proposed in this study to calibrate the concentration of C2H4. The high-precision Environics2000 automatic standard gas dispenser from the United States, which has a built-in CPU computer control and data control and processing system, was used. Its gas concentration accuracy: ± 1.0%, gas flow accuracy: ± 1.0%, gas repeatability accuracy: ± 1.0%, flow linearity accuracy: ± 0.5%, and inlet operating pressure: minimum 10 psig (0.67 bar) ~ 75 psig (5.04 bar). The measured and simulated WMS-2f/1f signals were multilinearly fitted using a multilinear fitting algorithm and wavelength modulation spectroscopy (WMS), and the measurement of C2H4 concentration was achieved based on the extracted spectral line information. The results show that the maximum relative error of C2H4 concentration measurement is 2.40%, which is 54% lower than that of the conventional 2f peak measurement method, thus demonstrating the effectiveness of the multilinear fitting algorithm in the inversion of C2H4 concentration under the interference of absorption lines. In addition, this study has far-reaching implications for the application of TDLAS technology in the accurate detection of coal spontaneous combustion indicator gases.
Sound trapping and waveguiding in locally resonant viscoelastic phononic crystals
Authors: Yip Kenny L. S. , John Sajeev 
Published: September 2023

AbstractWe describe the trapping and absorption of audible sound in centimeter-scale claddings of two-dimensional, locally resonant phononic crystals. In a square lattice of local resonators consisting of steel cores and cellulose shells, embedded in a viscous foam, dual acoustic-range band gaps extending from about 200 to $$2850 \text { Hz}$$

2850

Hz

are achieved. The spectral range consists of a low-frequency, local resonance gap, separated from a higher frequency Bragg resonance gap, by narrow bands of slow-sound modes. We demonstrate that thin claddings of such phononic crystal, of only three unit cells in thickness, can effectively prevent sound transmission, by a combination of reflection and absorption, over much of the audible spectrum. Moreover, frequency-selective sound transmission can be enabled by engineering waveguide channels that transmit sound through the local resonance gap, the Bragg gap, or both. This offers a path to sound-sculpting claddings that can surround a noise-generating source. The viscoelastic foam in our cladding is treated using a fractional Voigt model, capable of describing experimentally observed responses.
Investigation of blood group genotype prevalence in Korean population using large genomic databases
Authors: Bae Cheol O , Kwon Soon Sung , Kim Sinyoung 
Published: September 2023

AbstractBlood group antigens, which are prominently expressed in red blood cells, are important in transfusion medicine. The advent of high-throughput genome sequencing technology has facilitated the prediction of blood group antigen phenotypes based on genomic data. In this study, we analyzed data from a large Korean population to provide an updated prevalence of blood group antigen phenotypes, including rare ones. A robust dataset comprising 72,291 single nucleotide polymorphism arrays, 5318 whole-exome sequences, and 4793 whole-genome sequences was extracted from the Korean Genome and Epidemiology Study, Genome Aggregation Database, and Korean Variant Archive and then analyzed. The phenotype prevalence of clinically significant blood group antigens, including MNSs, RHCE, Kidd, Duffy, and Diego, was predicted through genotype analysis and corroborated the existing literature. We identified individuals with rare phenotypes, including 369 (0.51%) with Fy(a−b+), 188 (0.26%) with Di(a+b−), and 16 (0.02%) with Jr(a−). Furthermore, we calculated the frequencies of individuals with extremely rare phenotypes, such as p (0.000004%), Kell-null (0.000310%), and Jk(a−b−) (0.000438%), based on allele frequency predictions. These findings offer valuable insights into the distribution of blood group antigens in the Korean population and have significant implications for enhancing the safety and efficiency of blood transfusion.
A critical insight on nanofluids for heat transfer enhancement
Authors: Alami Abdul Hai , Ramadan Mohamad , Tawalbeh Muhammad , Haridy Salah , Al Abdulla Shamma , Aljaghoub Haya , Ayoub Mohamad , Alashkar Adnan , Abdelkareem Mohammad Ali , Olabi Abdul Ghani 
Published: September 2023

AbstractThere are numerous reports and publications in reputable scientific and engineering journals that attribute substantial enhancement in heat transfer capabilities for heat exchangers once they employ nanofluids as working fluids. By definition, a nanofluid is a working fluid that has a small volume fraction (5% or less) of a solid particle with dimensions in the nanoscale. The addition of this solid material has a reported significant impact on convective heat transfer in heat exchangers. This work investigates the significance of the reported enhancements in many recent related publications. Observations on these publications’ geographical origins, fundamental heat transfer calculations, experimental setups and lack of potential applications are critically made. Heat transfer calculations based on methodologies outlined in random selection of available papers were conducted along with a statistical analysis show paradoxically inconsistent conclusion as well as an apparent lack of complete comprehension of convective heat transfer mechanism. In some of the surveyed literature for example, heat transfer coefficient enhancements were reported to be up to 27% and 48%, whereas the recalculations presented in this work restrain proclaimed enactments to ~ 3.5% and − 4% (no enhancement), respectively. This work aims at allowing a healthy scientific debate on whether nanofluids are the sole answer to enhancing convective heat transfer in heat exchangers. The quantity of literature that confirms the latter statement have an undeniable critical mass, but this volition could be stemming from and heading to the wrong direction. Finally, the challenges imposed by the physical nature of nanoparticles, as well as economic limitations caused by the high price of conventional nanoparticles such as gold (80$/g), diamond (35$/g), and silver (6$/g) that hinder their commercialization, are presented.
Neuromuscular control in males and females 1 year after an anterior cruciate ligament rupture or reconstruction during stair descent and artificial tibial translation
Authors: Blasimann Angela , Busch Aglaja , Henle Philipp , Bruhn Sven , Vissers Dirk , Baur Heiner 
Published: September 2023

AbstractNeuromuscular alterations are reported in patients with anterior cruciate ligament reconstruction (ACL-R) and conservative treatment (copers with ACL deficiency, ACL-C). However, it is unclear whether sex influences neuromuscular control. The objective was to investigate differences in neuromuscular control regarding sex and treatment type one year after ACL rupture in comparison to a group with an intact ACL (ACL-I). Electromyography of vastus medialis (VM) and lateralis, biceps femoris (BF) and semitendinosus (ST) was recorded in ACL-R (N = 38), ACL-C (N = 26), and ACL-I (N = 38) during stair descent and reflex activity by anterior tibial translation while standing. The movements of stair descent were divided into pre-activity, weight-acceptance and push-off phases, reflex activity in pre-activation, short, medium (MLR), and long latency responses (LLR). Normalized root mean squares for each muscle of involved and matched control limb per phase were calculated and analyzed with two-way ANOVA (α = 0.05). During stair descent, neuromuscular differences of BF were significant during push-off only (p = 0.001). Males of ACL-R and ACL-C had higher BF activity compared to ACL-I (p = 0.009, 0.007 respectively). During reflex activity, VM and BF were significantly different between treatment groups for pre-activation (p = 0.013, 0.035 respectively). VM pre-activation of females was higher in ACL-R compared to ACL-C (p = 0.018), and lower in ACL-C compared to ACL-I (p = 0.034). Males of ACL-R showed higher VM and less BF pre-activation (p = 0.025, p = 0.003 respectively) compared to ACL-I. Males of ACL-C had less BF pre-activation compared to ACL-I (p = 0.019). During MLR, intra-group differences in ST were found for treatment (p = 0.011) and females of ACL-R compared to ACL-I (p = 0.015). During LLR, overall intra-group differences in VM were present for treatment (p = 0.034) and in females (ACL-R versus ACL-C (p = 0.015), ACL-I (p = 0.049), respectively). One year after an ACL rupture, neuromuscular alterations persist regardless of treatment and sex. Standard rehabilitation protocols may not be able to restore neuromuscular control. Future research should include long-term follow up and focus on exercises targeting neuromuscular function.
Arctic shipping trends during hazardous weather and sea-ice conditions and the Polar Code’s effectiveness
Authors: Müller Malte , Knol-Kauffman Maaike , Jeuring Jelmer , Palerme Cyril 
Published: September 2023

AbstractThe Arctic’s extreme environmental conditions and remoteness make it a complex and dynamic environment for maritime operators. We find that Arctic shipping has grown by 7% per year over the past decade, despite the hazardous weather and sea-ice conditions that pose risks to vessels operating in the region. As a result of a strong increase in winter sailing, the time ships operate in these extreme conditions has even tripled. To mitigate maritime risks, the Polar Code has been introduced. Among other things, it regulates Arctic shipping by specifying hazardous conditions with a sea-ice classification scheme and design temperature threshold. However, we argue that the Polar Code needs refinement through the integration of maritime warning systems and a broader description of hazardous conditions. This is supported by an analysis of shipping activity patterns in severe sea-spray icing conditions and a discussion of a recent sea-ice induced incident along the Northern Sea Route.