bluuebunny/crossref_metadata_2025_split huggingface dataset:
A new model of pregnacy-associated malaria for inducing adverse pregnancy outcomes in ICR mice
Authors: Zhang Yingying , Liang Zhiming , Xing Haoyu , Yu Chuyi , Liang Jianming , Xu Qin , Song Jianping , He Zhouqing 
Published: April 2023

Abstract
Backgroud：Based on understanding of placental pathological features and safe medication in pregnancy-associated malaria (PAM), establishment of a stable pregnant mice infection model with Plasmodium was urgently needed.
Methods: ICR mice were randomly divided into pre-pregnancy infection, post-pregnancy infection, and uninfected pregnancy cohorts. The mice were inoculated with 1×106 Plasmodium berghei ANKA-infected RBCs by intraperitoneal injection, and the same amount of saline was given to uninfected pregnancy group. We recorded the incidence of adverse pregnancy outcomes and the amounts of offspring in each group.
Results: The pre-pregnancy infection group mice were unable to conceive normally, and vaginal bleeding, abortion, or stillbirth appeared in the post-pregnancy infection group. The incidence of adverse pregnancy outcomes was extremely high and statistically significant compared with the control (Malaria-) group (P < 0.05), of which placenta exhibited pathological features associated with human gestational malaria.
Conclusions: The intraperitoneal injection of 1×106 Plasmodium berghei ANKA-infected RBCs can establish a murine model of post-pregnancy malaria infection.
Geo-environment intrinsic suitability evaluation to urban construction in Rongcheng district of Xiong’an New Area, China
Authors: LIU Hong-wei , HAN Bo 
Published: April 2023

Abstract
Xiong’an New Area is a national event and a project planned for a millennium of China. Its high-quality construction is of great significance to easing the non-capital functions of Beijing and the coordinated development of the Beijing-Tianjin-Hebei region. As an emerging city, the development and construction of Xiong’an New Area is bound to be restricted by geological and resources conditions. Therefore, geo-environment intrinsic suitability analysis is the necessary basis of urban development and construction. Geo-environment intrinsic suitability analysis to urban construction is a complex process that requires various geological indicators information and relevant expertise to analyze their relevance. This paper focuses on the analytic hierarchy process (AHP) for the assessment of geo-environment intrinsic suitability to urban construction in Rongcheng district which is a Start Construction Region in Xiong’an New Area. Multiple factors, including characteristic value of bearing capacity of foundation soil, land-subsidence rate, faults, ground fissures, potential liquefied sands, groundwater quality, soil quality, corrosion of groundwater to concrete, corrosion of groundwater to steel, enrichment of deep groundwater and geothermal resource, were used for the intrinsic suitability assessments. From our achievements, we note that suitable lands for urban construction located in most parts of the case study area with an acreage percentage of 90.9％. Meanwhile, for another 9.1% of the land, the impacts of faults, land-subsidence rate and potential liquefied sands need to be noted preferentially when urban construction.
Dynamic Stress Response Analysis of Inhomogeneous Medium Containing Inhomogeneous Inclusions under Action of SH Waves
Authors: Zhu Yun , Yang Zai-lin , Zhao Jian , Chen Yicun , Mi Yong-tao 
Published: April 2023

Abstract
An analytical model is proposed for the propagation of elastic waves in inhomogeneous substrates containing inhomogeneous inclusions (considering inhomogeneities in the modulus and density) based on elastic wave propagation in a homogeneous medium. The proposed method provides novel concepts and serves as a theoretical reference for determining the dynamic stress concentration and interface displacement in functionally graded material (FGM) composites. An inhomogeneous substrate containing inhomogeneous circular inclusions under the action of SH waves is taken as an example: the variations in the modulus and density are considered to have an exponential form for the inclusions and a power law form for the substrate, and the dynamic stress response in the substrate induced by the inclusions is analyzed. Calculation examples are used to determine the effects of the reference wavenumber in the substrate, the inclusion-to-substrate wavenumber ratio and the inhomogeneity in the substrate and inclusions on the dynamic stress concentration factor (DSCF) distribution at the periphery of the inclusions. The dynamic stress concentration induced by the inclusions is found to be sensitive to changes in the substrate heterogeneity. Increasing the inhomogeneity parameter of the substrate results in a sharp increase in the dynamic stress concentration around a circular inclusion. Finally, regulating the heterogeneity of the inclusions can reduce the dynamic stress concentration to some extent.
Measuring the capability of biological incident rescue teams in China: Based on fuzzy analytic Hierarchy Process
Authors: Yao Lulu , Zhao Chao , Zhang Yongzhong , Bai Song , Li Nan , Li Tiantian 
Published: April 2023

Abstract
Background: Emergency rescue offers an important means to effectively respond to disasters and quickly restore normalization afterwards. With the rapid development of biotechnology, it is crucial to evaluate rescue capability in response to bioterrorism incidents, yet there is a lack of specific measurement standards and complete evaluation system. The purpose of this article is to establish an evaluation system for emergency rescue capability during bioterrorism events.
Methods: The index was established through the improved Delphi method, while the fuzzy comprehensive evaluation model was established on the basis of AHP. Experts in disaster work and research were invited to rate indicator items using the Likert scale, calculating the degree of agreement for each indicator using the Kendall coefficient W to assess expert consensus, then screen and identify indicators using the cutoff method. The fuzzy comprehensive evaluation model was formed by calculating the weight of the judgment matrix.
Results: Over two rounds of expert inquiry, 11 experts participated in the improved Delphi study (the response rate was 100%), and the Kendall coordination coefficients of the first and second rounds were 0.303 and 0.632 respectively (P < 0.05). According to the comprehensive score, coefficient of variation and full score ratio, 5 first-level indicators and 25 second-level indicators were determined. A fuzzy comprehensive evaluation model based on AHP was established to evaluate the rescue response from bioterrorism.
Conclusions: The expert group reached a consensus on all indicators of the model and overall, the model has sound content validity. The next step is to transform the evaluation model into a scale, verify its operability, and apply it to actual evaluation work to promote capacity building across the biological incident rescue team.
Role Of Gastric pH In Post Pancreatectomy Hemorrhage After Pancreaticogastrostomy In Whipple Procedure
Authors: Riyaz Mohammad , Devakumar Satish , Kamal Harshit , Jeswanth Satyanesan 
Published: April 2023

Abstract

BACKGROUND: Postpancreatectomy hemorrhage (PPH) is one of the most severe complications after pancreaticoduodenectomy.
METHODS:This prospective study was done in a tertiary care center to find out the role of gastric pH in postpancreatectomy hemorrhage. The gastric pH study is done by Ryle’s tube aspiration – 1) fasting ph value 1 hour before surgery and second value after 48 hrs of surgery.
RESULTS: Of the total 27 patients who underwent Whipple’s procedure, 6 patients develop postpancreatectomy hemorrhage. On applying unpaired T test it was found that the difference was significant (p value <0.05) in the mean pH values among those with PPH when compared to those without PPH. The mean pH levels (mean ± Sd) among bleeders was 3.39 ± 1.80 and among non bleeder was 6.33 ± 1.03. The mean pH values were significantly lower in those where bleeding was present. The area under the curve of the ROC analysed and it was found that that the PH of 4.1 had maximum sensitivity (50%) and specificity (95.2%). Based on this, association between bleeding and PH value of 4.1 as cutoff was analysed using chi square test and it was found that the incidence of bleeding was significantly (p value <0.05) higher among those who had a PH value <4.1 (75%) compared to those with PH >4.1 (13%)

CONCLUSION:

Persistent low gastric pH is associated with increased risk of post pancreatectomy
Hemorrhage.Suppression of the intrinsic gastric acid secretion will be helpful in reducing the risk of bleeding after Pancreaticogastrostomy in Whipple procedure.
Effects of memory dependent heat transfer on the Rayleigh wave propagation in non-local micropolar thermoelastic medium
Authors: Ahmed Lukman , Sawhney Shruti , Singh Kulwinder 
Published: April 2023

Abstract
This paper presents the problem of Rayleigh wave propagation in a non-local micropolar thermoelastic material within the framework of memory-dependent heat conduction and Eringen's non-local theory of elasticity. The memory-dependent derivative in the heat conduction equation makes it possible to describe the memory effects on the current temperature field from the previous temperature state with a time delay parameter and is characterized by different kernel functions over the slipping interval. The secular equation of Rayleigh waves, describing the dependence of Rayleigh wave speed on the time delay parameter and non-local parameter, is obtained analytically under stress-free and thermally insulated/isothermal boundary conditions. In a particular case, the secular equation obtained is in agreement with previously published results. To analyze the effects of key factors such as the non-local parameter, delay parameter, and kernel functions on Rayleigh wave speed, numerical computations have been performed by considering the relevant parameters of an aluminum-epoxy composite material and depicted graphically. The graphical analysis shows that there are significant effects of non-locality in the material and memory-dependent heat transfer on the Rayleigh wave speed.
Ceftiofur Treatment of Sows Results in Long-Term Alterations in the Nasal Microbiota of the Offspring That Can Be Ameliorated by Inoculation of Nasal Colonizers
Authors: Blanco-Fuertes Miguel , Sibila Marina , Franzo Giovanni , Obregon-Gutierrez Pau , Illas Francesc , Correa-Fiz Florencia , Aragon Virginia 
Published: April 2023

Abstract
Background
The nasal microbiota of the piglet is a reservoir for opportunistic pathogens that can cause polyserositis, such as Glaesserella parasuis, Mycoplasma hyorhinis or Streptococcus suis. Antibiotic treatment is a strategy to control these diseases, but it has a detrimental effect on the microbiota. We followed the piglets of 60 sows from birth to 8 weeks of age, to study the effect of ceftiofur on the nasal colonization by these pathogens and the nasal microbiota when the treatment was administered to sows or their litters. We also aimed to revert the effect of the antibiotic on the nasal microbiota by the inoculation at birth of nasal colonizers selected from healthy piglets. Nasal swabs were collected at birth, and at 7, 15, 21 and 49 days of age, and were used for pathogen detection by PCR and bacterial culture, 16S rRNA amplicon sequencing and whole shotgun metagenomics. Weights, clinical signs and production parameters were also recorded during the study.
Results
The composition of the nasal microbiota of piglets changed over time, with a clear increment of Clostridiales at the end of nursery. The administration of ceftiofur induced an unexpected temporary increase in alpha diversity at day 7 mainly due to colonization by environmental taxa. Ceftiofur had a longer impact on the nasal microbiota of piglets when administered to their sows before farrowing than directly to them. This effect was partially reverted by the inoculation of nasal colonizers to newborn piglets and was accompanied by a reduction in the number of animals showing clinical signs (mainly lameness). Both interventions altered the colonization pattern of different strains of the above pathogens. In addition, the prevalence of resistance genes increased over time in all the groups but was significantly higher at weaning when the antibiotic was administered to the sows. Also, ceftiofur treatment induced the selection of more beta-lactams resistance genes when it was administered directly to the piglets.
Conclusions
This study shed light on the effect of the ceftiofur treatment on the piglet’s nasal microbiota over time and demonstrated for the first time the possibility of modifying the piglets’ nasal microbiota by inoculating natural colonizers of the upper respiratory tract.
Is the nuclear attraction just magnetic moment interaction between nucleons?
Authors: Zexin Cao , Ling Liu 
Published: April 2023

Abstract
By reexamining the magnetic moment interaction between nucleons, it is argued in this article that the formula for calculating magnetic induction generated by magnetic moments derived from electrodynamics under far-field conditions is unsuitable for calculating near-field interactions between magnetic moments. When nucleons undergo magnetic moment interactions under near-field conditions, there is a strong magnetic flux coupling, similar to that in a transformer circuit.By assuming magnetic flux quantization generated by nucleons, the magnetic induction intensity can reach 105 T, providing enough magnetic attraction to overcome the Coulomb repulsion. A reasonable explanation for the binding energy of atomic nuclei under magnetic moment interaction conditions was provided. It is suggested that the upper limit of binding energy resulting from the magnetic moment interaction between protons and neutrons is approximately 125 MeV. The article analyzes the possibility of the existence of 2He nuclei composed of only protons and explores the relationship between neutron decay and strong magnetic fields. In the analysis of the magnetic structure of 4H nucleus, it is pointed out that the magnetic moment interaction is likely the fundamental reason for nuclear force saturation and multi-body force.A reasonable explanation for nuclear force can be provided through the hypothesis of nucleon magnetic flux quantization and the modification of the magnetic moment-field formula derived under far-field conditions. It suggests that nuclear force and strong interaction are likely to be electromagnetic forces. Furthermore, atomic nuclei may only be made up of buckyballs with equal amounts of positive charge and no net charge.
Widespread annual occurrence of pesticides within designated Critical Habitats for Endangered prairie butterflies
Authors: Runquist Erik , Nordmeyer Cale , Stapleton Seth 
Published: April 2023

Abstract
Insect declines have become pronounced in prairie ecosystems, particularly in areas of agricultural intensification. Non-target pesticide exposure has been raised as a key concern for prairie remnant health. We do not understand the extent of that exposure risk, particularly across seasons and multi-year timeframes. Over nine years, we analyzed grass and soil samples for the presence of hundreds of pesticides from five prairies in Minnesota and South Dakota that are designated as Critical Habitat for two endangered butterflies: Poweshiek skipperling and Dakota skipper. We found dozens of pesticides across all sites and years on their larval host grasses. Interiors of prairies were not less likely to have detectable pesticides than prairie-agriculture edges. Broad-spectrum organophosphate and pyrethroid insecticides were common in late season. Chlorpyrifos quantities were higher at sites where both endangered species have been extirpated. Few pesticides were detected in soil or early season grass samples. The risk associated with the prevalence and quantities of pesticides we observed likely underestimates the overall risk. Implications for Conservation: Our work demonstrates protected prairies are not immune to the risk of pesticide exposure, and that this may impact planned efforts to re-establish lost populations of imperiled prairie insect species, including endangered butterflies.
WITHDRAWN: Long-term, Single-Center Study Comparing Open and Laparoscopic Procedures for Congenital Midureteral Obstruction in Children
Authors: Zhou Guanglun , Jiang Man , Yin Jianchun , Liu Xiaodong , Sun Junjie , Li Shoulin 
Published: April 2023

Abstract
Purpose To compare the safety and outcomes of open and laparoscopic procedures in the management of congenital midureteral obstruction in children (CMO).Methods Between February 2008 and February 2022, a total of 18 patients underwent open ureteroureterostomy (OU group), and 26 underwent laparoscopic ureteroureterostomy (LU group). The operative time, postoperative hospital stay, hospital costs, postoperative complications, and success rates of the two groups were compared.Results The median age of the patients was 59 months, with 29 patients presenting with asymptomatic hydronephrosis, 12 with intermittent abdominal pain, and 3 with flank mass. The median follow-up time was 42 months, and all patients were successfully treated surgically. The operative time and postoperative hospital stay in the LU group were shorter than those in the OU group (106.3 ± 21.4 vs. 85.8 ± 16.5 min, 11.6 ± 1.9 vs. 8.3 ± 1.7 days, respectively; p < 0.05). The OU group had 2 postoperative complications: 1 case of wound infection and 1 case of febrile urinary tract infection. One case of postoperative urinary tract infection occurred in the LU group.Conclusions Our data showed that laparoscopic ureteroureterostomy is a safe and effective treatment for congenital midureteral obstruction in children, and provides several advantages, including fewer postoperative complications, shorter postoperative hospital stay, and a shorter operative time. Laparoscopic procedures should be the first choice for treating children with congenital midureteral obstructions.
Electrophysiological activity from the eye muscles, cerebellum and cerebrum during reflexive and voluntarily timed blinks
Authors: Todd Neil , Govender Sendhil , Keller Peter , Colebatch James 
Published: April 2023

Abstract
We report an experiment to investigate the role of the cerebellum and cerebrum in motor learning of timed movements. Eleven healthy human subjects were recruited to perform two experiments, the first a classical eye-blink conditioning procedure with an auditory tone as conditional stimulus (CS) and vestibular unconditional stimulus (US) in the form of a double head-tap. In the second experiment subjects were asked to blink voluntarily in synchrony with the double head-tap US preceded by a CS. Electrophysiological recordings were made of extra-ocular EMG and EOG at infra-ocular sites (IO1/2), EEG from over the frontal eye-fields (C3’/C4’) and from over the posterior fossa over the cerebellum for the electro-cerebellogram (ECeG). The behavioural outcomes of the experiments showed weak reflexive conditioning for the first experiment despite the double tap but robust well-synchronised voluntary blinks for the second. Voluntary blinks were larger than the reflex ones. For the voluntary task a contingent negative variation (CNV) was also present in the EEG leads prior to movement, and modulation of the high-frequency EEG occurred during movement. Stimulus-related cerebellar activity was prominent in the high-frequency ECeG for both conditions, while movement-related cerebellar activity was additionally present in the voluntary condition. These results demonstrate a role for the cerebellum in voluntary timed movement analogous to that in classical conditioning.
Magnetic resonance imaging of the dromedary camel carpus
Authors: Nahas Ayman El , Hagag Usama 
Published: April 2023

Abstract

Background: The dromedary camel (camelus dromedarius) carpal joint presents multiple joints and constitutes several bones and soft tissues. Radiography and/or ultrasonography of the carpus are challenging due to structural superimposition. High-field magnetic resonance imaging (MRI) technique precludes superimposed tissues and offers high soft tissue contrast in multiple sequences and planes. Hence, understanding the normal MRI anatomy is crucial during clinical investigations. Magnetic resonance imaging is highly sensitive for investigation of soft tissues and articular cartilage; therefore, it is extensively used for outlining joint anatomy and evaluation of a wide range of musculoskeletal conditions. MRI images of a specific anatomical region acquired by using multiple sequences in various planes are necessary for a complete MRI examination. Given the dearth of information on the MRI features of the dromedary camel carpus, the current study demonstrates the MRI appearance of the clinically significant structures in the camel carpus in various sequences and planes using a high-field 1.5 Tesla superconducting magnet. For this purpose, twelve cadaveric forelimbs, obtained from 6 clinically sound lameness free adult dromedary camels, were examined.
Results: The cortex and medulla of the radius, carpal bones and metacarpus were evaluated. Articular cartilage of the carpal joints was depicted and showed intermediate intensity. Carpal tendons expressed lower signal intensity in all pulse sequences. The collateral and inter-carpal ligaments showed mixed signal intensity.
Conclusions: The obtained data outlines the validation of MRI for investigation of the camel carpus and could set as a reference for interpretation in clinical patients.
Genomic, transcriptomic and epigenomic sequencing data of the B- cell leukemia cell line REH
Authors: Wiklander Mariya Lysenkova , Övernäs Elin , Lagensjö Johanna , Raine Amanda , Petri Anna , Wiman Ann-Christine , Ramsell Jon , Marincevic-Zuniga Yanara , Gezelius Henrik , Martin Tom , Bunikis Ignas , Ekberg Sara , Erlandsson Rikard , Larsson Pontus , Mosbech Mai-Britt , Häggkvist Susana , Kerje Susanne Hellstedt , Feuk Lars , Ameur Adam , Liljedahl Ulrika , Nordlund Jessica 
Published: April 2023

Abstract
Objectives

The aim of this data paper is to describe a collection of 33 genomic, transcriptomic and epigenomic sequencing datasets of the B-cell acute lymphoblastic leukemia (ALL) cell line REH. REH is one of the most frequently used cell lines for functional studies of pediatric ALL, and these data provide a multi-faceted characterization of its molecular features. The datasets described herein, generated with short- and long-read sequencing technologies, can both provide insights into the complex aberrant karyotype of REH, and be used as reference datasets for sequencing data quality assessment or for methods development.

Data Description

This paper describes 33 datasets corresponding to 450 GB of raw sequencing data generated from the REH cell line. These datasets include five different approaches for whole genome sequencing (WGS) on four sequencing platforms, two RNA sequencing (RNA-seq) techniques on two different sequencing platforms, DNA methylation sequencing, and single-cell ATAC-sequencing.