bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Effective Cough on Sputum Expulsion in Patients with ARI (Acute Respiratory Infection)
Authors: Ruswadi Indra , Roy Andri Yani  , Tia Karlina  , Fika Amalia  
Published: September 2023

ISPA or ARI (Acute Respiratory Infection) is an acute respiratory illness that lasts about 14 days and usually affects the throat, nose and lungs. A frequent problem in patients with acute respiratory infections is the inability to clear secretions from the airways which can lead to ineffective airway clearance. One of the non-pharmacological management of ARI can be done with effective cough training. The purpose of this study was to determine the effect of effective cough on sputum discharge in patients with ARI at Sumber Kasih General Hospital, Cirebon City in 2022.
This research design uses pre experiment with one group pre test-post test design. The research subjects were 90 ARI patients at Sumber Kasih General Hospital, Cirebon City with the sampling technique used was accidental sampling. The research instrument was a sputum discharge observation sheet.
The results of the study obtained data from the pretest results showed that sputum discharge in patients with ARI before effective cough training was carried out in the outgoing category, namely 54 people (60%). While the results of the posttest showed that sputum discharge in patients with ARI after effective coughing exercises with the outgoing category was 81 people (90%). Based on the results of the Wilcoxon test, the significance value (sig.2-tailed) <0.05 (p=0.000), then based on the decision-making criteria, Ha is accepted, meaning that effective cough training can increase sputum discharge in patients with ARI at Sumber Kasih General Hospital, Cirebon City.
It is hoped that nurses can provide education about effective cough training to increase sputum discharge in patients with ARI, so that patients with ARI are able to practice it at home
The lunar effect on delivery and other birth outcomes in rural Zambia
Authors: Stringer J M. , Sindano N , Vwalika B 
Published: September 2023

Objective: It is a widely held belief that the period of a full moon is associated with higher birth rates compared to periods when the moon is not full. We investigated whether more births occurred during a full moon in a rural African population.Design: Data collected from 42 clinical sites in rural Zambia associated with the Better Health Outcomes through Mentoring and Assessment (BHOMA) Study were evaluated. We compared the proportion of pregnancies born during a full moon to theproportion that would be expected if there were no association.Main outcomes: Proportion of births during the full moon.Measures: Demographics and birth outcomes.Results: A total of 10,127 women delivered at a participating site between 8 December 2010 and 19 August 2015. Mean maternal age was 25.1 years (standard deviation [SD] 6.4 years), mean maternal weight 62.7 kg (SD 13.9 kg), 14.4% were HIV seropositive, and 3.7% were syphilis positive. The mean birth weight was 3032 g (SD 0.5 g); 49.6% newborns were female, and 1.48% were stillborn. There was a full moon during 70 of the 1715 days under observation. In the absence of an association, we would expect 70 / 1715 (4.08%) of births to occur on these days. We observed a total of 434deliveries (4.29%; 95% Confidence Interval [CI]: 3.89%, 4.68%) during these 24-hour periods. Thus, an association between the full moon and higher delivery rates was not observed (p=0.87). An additional analysis, where the entire lunar cycle was divided into 8 equal bins, also yielded no association. Finally, we did not identify any other birth outcomes that were associated with lunar cycle (birthweight, stillbirth, gender, or congenital malformation).Conclusions: In this large, rural population, we found no evidence of a lunar effect on delivery or adverse birth outcomes. These results refute a common belief and should provide assurance to managers who opt to ignore lunar cycle when scheduling midwife staffing of rural clinics.
The Negative View of Iraqi Law on the Crimes of Witchcraft and Sorcery
Authors: Hayder Lana Majid , Halim Asma Hakimah Ab , Awal Noor Aziah Mohd , Hashim Fatimah Yusro 
Published: September 2023

Objective: The article aims to highlight the serious crime that the law remained oblivious to it whether in treatment or criminalizing it. Although all monotheistic religions recognize it, the position of the Arab legislator differed from that. Some of them put an explicit text criminalizing witchcraft as a separate offense, and some put it under the crime of fraud, including the Iraqi Penal Code. Methodology: This article explains the nature of witchcraft and the methods used for it, and clarified the effect of witchcraft on the individual and society, and the witchcraft crime in terms of human rights. It will also look at the views of the Islamic religion, in relation to witchcraft and sorcery and the position of the Iraqi legislator and some Arab countries on it. Result and discussion: The crime of witchcraft is an independent crime and cannot be considered a crime of fraud due to the seriousness of its consequences according to the legislation in some Arab countries such as Saudi Arabia and the United Arab Emirates. Conclusions: Man has practiced magic and sorcery throughout the ages, and surprisingly, they are still practicing it in the current era, on a large scale. It submitted that the crime of witchcraft should not be considered as one of the crimes of fraud. It is necessary to put a specific article that applies to the real act (witchcraft and sorcery) and mind it as one of the most dangerous acts that the legislator must face with the harshest penalties.
Adoption of Cloud-Based Accounting to Achieve Sustainable Development in Banking Industry: A Case of Indonesia
Authors: Ria Ria 
Published: September 2023

Objective: This study aims to explain the factors that influence of cloud accounting adoption in the Banking industry by applying the technology acceptance model (TAM) and technology-organization-environment (TOE).

Methods: The research method that was evaluated empirically used survey data from employee in banking industry. Data processing was carried out using Partial Least Squares-Structural Equation Modeling (PLS-SEM).

Result: The results showed that management support, organizational competence, service quality, system quality, perceived usefulness and perceived ease of use had a significant relationship with intention to use cloud accounting. The intention to adopt of cloud accounting had a significant relationship to the use of cloud accounting.

Conclusions: This research contributes to a theoretical understanding of the factors that enable the intention to adoption of cloud accounting while providing benefits to financial firms in general that enable them to further develop cloud accounting frameworks.
Cabergoline and Low-Dose Steroid Therapy İn Idiopathic Granulomatous Mastitis
Authors: DURGUN Cemalettin 
Published: September 2023

Introduction: Idiopathic granulomatous mastitis(IGM) is a rare, chronic granulomatous inflammatory disease of the breast. It is mostly seen in young women with a history of breastfeeding. It typically presents as a painful lump in the breast, erythema, focal abscess formation, skin ulceration, or fistula. The etiology and pathogenesis of IGM could not yet be well understood. It is thought to be caused by a localized autoimmune response against fat and protein-rich secretions leaking from the lobules due to previous hyperprolactinemia. There is no definite treatment protocol defined for IGM. Pharmacological agents and surgical interventions are used alone or in combination in the treatment. In this study, we aimed to examine the results of patients who were treated with cabergoline and low-dose steroids for IGM in our center.
Methods: In this study, the files of patients who were treated with cabergoline and steroids for idiopathic granulomatous mastitis in our clinic were reviewed retrospectively. 36 patients were included in the study. The patients were invited to the outpatient clinic for the final examination. Demographic characteristics of the patients, symptoms at presentation, examination findings, laboratory tests, radiological imaging, tru-cut biopsy results, microbiological culture results, treatment doses and durations, remission times, surgery requirements, and recurrence were recorded.
Results: All 36 patients included in the study were women of childbearing age. The most common presenting complaint was a palpable painful mass. Abscesses were present in 12 patients. Ulcers were observed in 9 patients and fistulas were observed in 4 patients. The most common involvement was in the lower outer quadrant. S.aureus was detected in the culture of 1 patient. Complete recovery was observed in 20 of 36 patients as a result of the treatment. The mean duration of remission was 2.85±2.54 months. The treatment of 29 (74.3%) patients was completed medically. Surgical excision was performed in 7 patients with a residual lump. No recurrence was observed during the follow-up period of 27.88 ± 8.21 months.
Conclusion: The treatment of IGM is still controversial. The fact that cabergoline and low-dose steroid therapy provides remission in a short time, minimizes the need for surgery, and does not relapse in medium-term follow-up shows that it is a successful option in IGM treatment.
Effect of cardio-gastric interaction on atrial fibrillation in GERD patients
Authors: GÜNLÜ Serhat , ARAÇ Eşref , AKTAN Adem , KAYAN Fethullah , ALTINTAŞ Bernas , KARAHAN Mehmet Zülkif 
Published: September 2023

Objective: Atrial fibrillation (AF) and gastroesophageal reflux disease (GERD) are very common in daily clinical practice. Post-prandial AF episodes have been reported in GERD patients. Although it was reported in previous studies that it was caused by sympathovagal imbalance, there are no studies on cardiac conduction system involvement. In this study, we aimed to evaluate whether the risk of developing AF increases in untreated GERD patients with non-invasive electrophysiological tests.
Methods: The research was prospectively performed. Endoscopy was performed on the individuals due to reflux complaints. ECG was recorded at 25mm/s and 10 mm/mV amplitude, and 24-hour Holter ECG (three-channel; V1, V2, and V5) was performed. ECG parameters were measured and Holter ECG results were analyzed.
Results: A total of 120 individuals, 60 patients and 60 controls, were included. No significant statistically differences existed between groups for hypertension, diabetes, smoking, or dyslipidemia (p>0.05). In terms of heart rate, Pmax, Pmin, QTd, and QTcd, there were no significant differences across the two groups (p>0.05). P-wave dispersion (Pd) was substantially higher in the study group (p=0.014). Comparing the heart rate variabilities of 24-hour Holter ECG recordings across the groups, the standard deviation of R-R intervals (SDNN) was substantially higher in the study group (p
The Role of Steroid Receptors in the Proliferation and Migration of Endometrial Adenocarcinoma HEC1A Cell Line
Authors: HENNAWİ Khairat Al , TİFTİK R. Nalan , ÜN İsmail , BÜYÜKAFŞAR Kansu 
Published: September 2023

Objectives: Endometrial carcinoma is one of the most common gynecological cancers. It is generally divided into oestrogen-dependent type I, and oestrogen-independent type II. Although the expression of some steroid receptors has been documented in type II endometrial carcinoma, their roles in tumor progression have not been fully elucidated yet. Thus in this study, we aimed to examine the role of compounds acting on steroid receptors in type II, on HEC1A cultured cells.
Methods: We tested the effect of mifepristone (the glucocorticoid and progesterone receptor blocker, 10-8M), bicalutamide (the androgen receptor blocker, 10-6M), G15 (the G-protein-coupled estrogen receptor-1 blocker, 10-7M) and PHTPP (2-Phenyl-3-(4-hydroxyphenyl)-5,7-bis (trifluoromethyl)-pyrazolo [1,5-a]pyrimidine, the estrogen receptor-β blocker, 10-7M), on proliferation. Proliferation was assessed by xCELLigence analysis system and migration was examined by using wound-healing model.
Results: None of the drugs, at the used concentrations, have affected the proliferation of HEC1A cells. However, migration was significantly increased at the 24th and the 48th hour of mifepristone application (p
Examination of Radiological Findings and Clinical Parameters in Paediatric Patients with Covid-19
Authors: TASTEKİN POLAT Zeynep Ece , YILMAZ Kamil , TURMAK Mehmet 
Published: September 2023

Objective: It was aimed to evaluate the relationship between imaging techniques and clinical and laboratory parameters in paediatric COVID-19 patients.
Methods: Our study included 187 patients under the age of 18 whose diagnosis of COVID-19 was confirmed by PCR test. Demographic, clinical, laboratory and radiological imaging findings of the patients were reviewed retrospectively from their file records.
Results: 57.2% of the patients were male and the mean age was 110.1±67.4 months. A pulmonary finding associated with COVID-19 was detected in 21 (12%) of 175 patients who underwent Posterior-anterior (PA) chest X-ray. The most common findings were consolidation (n=16; 9.1%), bilateral ground-glass appearance (n=11; 6.3%), and atelectasis (n=5; 2.9%), respectively. Computed lung tomography was performed in 67 of the patients. The presence of a pulmonary finding associated with COVID-19 was detected in 28 (41.8%) of these patients. The three most common findings were consolidation (n=16; 23.9%), bilateral ground glass appearance (n=16; 23.9%), and atelectasis (n=15; 22.4%), respectively. It was determined that for patients with imaging findings on PA X-ray needed more paediatric intensive care, the length of their hospital stay was longer, comorbid diseases were present, their cough and tachypnea complaints were more pronounced (p
Akut Pankreatitte Tiyol Disülfit Homeostazı Hastalık Lehine Bozulmaktadır
Authors: YÜREKLİ Uğur Fahri , UĞURLU Esat Taylan 
Published: September 2023

Giriş ve Amaç: Akut pankreatit (AP) cerrahi kliniklerinin en çok uğraştığı hastalıklardandır. Mortalite oranları tüm olgularda yaklaşık %1 düzeyinde iken, bu rakam pankreatik nekroz olgularında %15’ler düzeyine çıkabilir. Bu nedenle nekrotizanpankreatittepatogenezinin aydınlatılması çok önemlidir. AP de tiyoldisülfit dengesinin (TDH) bozulduğu gösterilmiştir. Ancak nekrotizan pankreatite bu durum hala belirsizliğini korumaktadır. Bu çalışmanın amacı akut nekrotizan pankreatiteTDH’ını belirlemek ve bu parametrenin nekrotizan pankreatit ön tanısında kullanımını ortaya koymaktır.
Yöntemler: Bu çalışmaya akut pankreatit tanısıyla kliniğimize yatırılan 160 hasta ve 100 sağlıklı kontrol dahil edildi. AP hastaları tomografi sonuçlarına göre akut nekrotizan pankreatit (ANP) ve akut ödematözpankreatit (AEP) olarak iki gruba ayrıldı. Kontrol ve hastaların total ve nativeti yol değerleri ölçüldü; Redükte tiyol, oksidize tiyol ve tiyoloksidasyon/redüksiyon oranları bu parametrelerden hesaplandı. Gruplar arasında tespit edilen farklar istatistiksel olarak analiz edildi. AEP ve ANP gruplarından elde edilen sonuçlar ROC analizi ile kıyaslanarak TDH’ın erken tanıdaki etkinliği belirlendi.
Bulgular: Kontrol gurubuyla kıyaslandığında AEP ve ANP hastalarında redükte (reduced) tiyoloranı ve tiyoloksidasyon/redüksiyon oranının düştüğü bulundu. ANP erken tanısında redükte tiyol oranının (AUROC: 0,979, sensitivite: %98,3 ve spesifite %92,0) kullanılabileceği bulundu.
Sonuç: AP’de oksidatif stres artışına TDH bozulması katkı sunmaktadır. Bu denge AEP ile kıyaslandığında ANP’de daha fazla bozulmaktadır. ANP tanısında TDH belirteç olarak kullanılabilir.
Zorunlu Göçle Gelip Çadırkentte Yaşayan Ezidi Kadınların Doğurganlık Özellikleri ve Anemi Düzeylerinin Değerlendirilmesi
Authors: KILINÇ Zehra , YİĞİTALP Gülhan , EVİNÇ Evin , ÖZCAN Nida , CEYLAN Ali , ÖZEKİNCİ Tuncer 
Published: September 2023

Giriş ve Amaç: Doğurganlık çağındaki kadınlar tüm olağanüstü durumlarda olduğu gibi savaşlarda ve zorunlu göçlerde de en riskli gruplar arasındadır. Bu çalışma zorunlu göç ile ilimize gelen Ezidi kadınların doğurganlık özelliklerini, aile planlaması yöntemi kullanma durumlarını ve doğum öncesi/sonrası bakım hizmeti alıp almadıklarını, anne ve bebek sağlığı için önemli bir gösterge olan hemoglobin düzeylerini değerlendirmek amacıyla yapıldı.
Yöntemler: Tanımlayıcı kesitsel tipte olan bu çalışma, Temmuz 2015-Şubat 2016 tarihleri arasında Diyarbakır Büyükşehir Belediyesine bağlı bir çadır kentte yaşayan 15-49 yaş arası evli kadınlarla yapıldı. Çalışmanın evreni çadır kentte yaşayan 15-49 yaş evli kadınlar idi. Çadır kentteki 15-49 yaş evli kadın sayısı 580 idi. Örnekleme alınma kriterlerini sağlayan toplam 248 kişi araştırmaya kapsamına alındı. Kadınlara yüz yüze görüşme tekniği kullanılarak sosyodemografik bilgileri ve doğurganlık özellikleri ile ilgili 35 sorudan oluşan bir anket uygulandı. Kadınlardan aseptik koşullarda yaklaşık 5 mililitre venöz kan alındı. Örnekler 12 saat içerisinde Dicle Üniversitesi Hastanesi Merkez Laboratuvarı'na gönderildi, Cell-Dyn Ruby Hematology Analyzer (Abbott, ABD) otomatize sistemi ile hemoglobin düzeyleri belirlendi.
Bulgular: Çalışmaya katılan kadınların %72,6’sı okuryazar değildi. Kadınların ortalama evlenme yaşı 17,8±3,4, ilk doğum yaşı 19,4±3,3, doğum sayıları 4,6±3,2, yaşayan çocuk sayıları 4,1±2,8 ve sahip olmak istedikleri çocuk sayısı 4,7±2,2 idi. Aile planlaması yöntemleri ile ilgili bilgisi olanların oranı %83,9, çalışmanın yapıldığı dönemde aile planlaması yöntemi kullananların oranı %50 idi. Kadınların %10,1’i Türkiye'ye geldikten sonra doğum yapmış ve bunların %72’si doğum öncesi bakım, %40’ı doğum sonrası bakım hizmeti almıştı. Eğitim almamış/ilkokul bitirmemiş kadınların aile planlaması yöntemi kullanma oranı ve aile planlaması hakkında bilgisi ilkokul ve üstü bir okul bitirenlerden daha yüksek olup gruplar arasındaki fark istatistiksel olarak anlamlı bulundu (p
กลยุทธ์การบริหารทุนมนุษย์ของวิทยาลัยอาชีวศึกษาเอกชนตามแนวคิดคุณลักษณะนักศึกษาอาชีวศึกษาสำหรับประชาคมอาเซียน
Authors:   , จันทร์เจริญ อิศเรศ 
Published: September 2023

การวิจัยครั้งนี้มีวัตถุประสงค์เพื่อ 1)ศึกษากรอบแนวคิดการบริหารทุนมนุษย์ของวิทยาลัยอาชีวศึกษาเอกชนตามแนวคิดคุณลักษณะนักศึกษาอาชีวศึกษาสำหรับประชาคมอาเซียน 2)ศึกษาสภาพปัจจุบันและสภาพที่พึงประสงค์ของการบริหารทุนมนุษย์ของวิทยาลัยอาชีวศึกษาเอกชนตามแนวคิดคุณลักษณะนักศึกษาอาชีวศึกษาสำหรับประชาคมอาเซียน 3)ศึกษาจุดแข็ง จุดอ่อน โอกาส และภาวะคุกคามของการบริหารทุนมนุษย์ของวิทยาลัยอาชีวศึกษาเอกชนตามแนวคิดคุณลักษณะนักศึกษาอาชีวศึกษาสำหรับประชาคมอาเซียน 4)พัฒนากลยุทธ์การบริหารทุนมนุษย์ของวิทยาลัยอาชีวศึกษาเอกชนตามแนวคิดคุณลักษณะนักศึกษาอาชีวศึกษาสำหรับประชาคมอาเซียน ดำเนินการวิจัยโดยใช้ระเบียบวิธีวิจัยแบบผสมผสาน เก็บรวบรวมข้อมูลจากผู้บริหารวิทยาลัยอาชีวศึกษาเอกชนจำนวน 176 คน ครู184 คน รวม 360 คน เครื่องมือที่ใช้ในการวิจัยคือแบบสอบถาม แบบประเมินกรอบแนวคิดการวิจัย และแบบประเมินความเหมาะสมและความเป็นไปได้ของกลยุทธ์ วิเคราะห์ข้อมูลโดยใช้สถิติ ความถี่ ร้อยละ ค่าเฉลี่ย ส่วนเบี่ยงเบนมาตรฐาน ค่าดัชนีPNImodified และการวิเคราะห์เนื้อหาจากการสนทนากลุ่ม

ผลการวิจัยพบว่า1)กรอบแนวคิดในการวิจัยเกี่ยวกับการบริหารทุนมนุษย์ของวิทยาลัยอาชีวศึกษาเอกชนฯ ประกอบด้วย 3 กระบวนการ ได้แก่ (1) การสรรหาคัดเลือกบุคลากร (2) การพัฒนาบุคลากร (3) การบริหารผลงานและค่าตอบแทน และคุณลักษณะนักศึกษาอาชีวศึกษาสำหรับประชาคมอาเซียน ประกอบด้วย คุณลักษณะ 3 ด้าน ได้แก่ (1) ด้านความรู้ ประกอบด้วย ความรู้พื้นฐานเกี่ยวกับประชาคมอาเซียน และความรู้ทางทฤษฎีและวิชาชีพ (2) ด้านทักษะ ประกอบด้วย ทักษะทางภาษาต่างประเทศ ทักษะทางวิชาชีพ ทักษะทางเทคโนโลยี และทักษะทางด้านการทำงานเป็นทีม (3) ด้านเจตคติ ประกอบด้วย ความภูมิใจในความเป็นชาติ การยอมรับความแตกต่างด้านวัฒนธรรม และทัศนคติที่ดีต่อวิชาชีพ 2) สภาพปัจจุบันของการบริหารทุนมนุษย์ของวิทยาลัยอาชีวศึกษาเอกชนในภาพรวมอยู่ในระดับมาก เรียงลำดับดังนี้ การพัฒนาบุคลากร การสรรหาคัดเลือกบุคลากร การบริหารผลงานและค่าตอบแทน ส่วนสภาพที่พึงประสงค์อยู่ในระดับมากที่สุด คือ การพัฒนาบุคลากร การสรรหาคัดเลือกบุคลากร ทั้งนี้ การบริหารผลงานและค่าตอบแทน อยู่ในระดับมาก 3) จุดแข็งในการบริหารทุนมนุษย์ของวิทยาลัยอาชีวศึกษาเอกชนตามแนวคิดคุณลักษณะนักศึกษาอาชีวศึกษาสำหรับประชาคมอาเซียนคือ การพัฒนาบุคลากร ส่วนจุดอ่อนคือ การบริหารผลงานและค่าตอบแทน และการสรรหาการคัดเลือกบุคลากร โดยพบว่า มิติของด้านเจตคติของทุกด้านเป็นจุดแข็ง ส่วนมิติด้านความรู้และด้านทักษะของทุกด้านเป็นจุดอ่อน โอกาสคือ สภาพเทคโนโลยี ภาวะคุกคามคือ สภาพเศรษฐกิจ นโยบายของรัฐ และสภาพสังคม ตามลำดับ 4) กลยุทธ์การบริหารทุนมนุษย์ของวิทยาลัยอาชีวศึกษาเอกชนตามแนวคิดคุณลักษณะนักศึกษาอาชีวศึกษาสำหรับประชาคมอาเซียน ประกอบด้วย กลยุทธ์หลัก 3 กลยุทธ์ กลยุทธ์รอง 9 กลยุทธ์ โดยมีกลยุทธ์หลักคือ 1) ปฏิรูปการบริหารผลงานและค่าตอบแทนมุ่งผลลัพธ์การเสริมสร้างคุณลักษณะนักศึกษาอาชีวศึกษาสำหรับประชาคมอาเซียน 2) เพิ่มขีดความสามาถในการสรรหาคัดเลือกบุคลากรใหม่มุ่งผลลัพธ์การเสริมสร้างคุณลักษณะนักศึกษาอาชีวศึกษาสำหรับประชาคมอาเซียน 3) พัฒนาสมรรถนะบุคลากรมุ่งผลลัพธ์การเสริมสร้างคุณลักษณะนักศึกษาอาชีวศึกษาสำหรับประชาคมอาเซียน
New Edta-based drug delivery carrier
Authors:   , Pangkom Nathapong 
Published: September 2023

Most of the anticancer drugs are insoluble in water, unspecified to target site and degradable under acidic conditions in the stomach, resulting in decreasing their activities and increasing the side effects. To overcome these problems, drug delivery carriers were used to overcome these problems. Most of the drug delivery carriers were prepared by polymeric micelle systems. However, that of polymeric micelle systems are difficult to synthesize into the random polymers, where different units are aligned on a polymer chain in a random manner, immature drug-incorporation technology and possible chronic liver toxicity due to slow metabolic process. Therefore, the enhancement of anticancer drugs solubility, the pH-sensitive with safe, inexpensive condition and improvement of the selectivity were studied. Ethylenediaminetetraacetic acid (EDTA) derivative self-assembly micelles have been proposed and investigated for their potential as drug carriers. In this work, EDTA was synthesized to present both hydrophobic moiety and cancer targeting moiety in order to create self-assembly micelles and increase selectivity to the cancer cell. The EDTA was modified with hydrophobic part (octadecyl bromide: Oc) and cancer targeting (folic acid: FA) to Oc-EDTA-FA. The structure, critical micelles concentration and the morphologies of Oc-EDTA-FA were characterized by spectroscopic methods and scanning electron microscopy (SEM). The cytotoxicity of Oc-EDTA-FA self-assembly micelles as cancer drug delivery carriers was investigated by MTT assay. The results showed that Oc-EDTA-FA was successfully synthesized, self-assembled Oc-EDTA-FA micelles could be easily prepared by re-dispersion in distilled water and they were pH-sensitive and acid resistance. In addition, Oc-EDTA-FA carrier exhibited an effectiveness of cytotoxicity against cancer cells which showed the highest efficiency to the SW620 cancer cells over other cancer cells. The Oc-EDTA-FA@Cur carrier gave more specific to cancer cells than normal cells significantly. Therefore, the Oc-EDTA-FA self-assembled micelles were suitable to use in the application of drug delivery carrier.