bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exoskeleton For Specially Abled
Authors: Wani Vaibhav Anil , Shaikh Mohd Shahed , Shewale Yash S , Nair Sreelakshmi M 
Published: August 2023

Abstract
This is a paper about a wearable exoskeleton that addresses the lack of assistive devices for people with walking difficulties. The research revolves around the major problem in which the inpatient suffer for their dependency on a caretaker for basic tasks such as toiletries and fetching water or food or even for basic cores for themselves. People with disabilities suffer from many social and mental pressures due to exclusion from society just for being different from normal human beings. Hence, the usage and purpose of robotic technology trims down this segregation and promote vocational incorporation.
Assessment of the level of Heavy Metals in Ecosystem around Quarry site in Ogun State, Nigeria
Authors: Ogunmade Taiwo B. , Adeyemi Olufemi O. , Osobamiro Temitope M. , Olubusoye Boluwatife S. , Alabi Oluwatobi 
Published: August 2023

Abstract

This study investigated the anthropogenic impacts of quarrying activities on the ecosystem. Soil, rock, water, and plant samples were collected at varying distances around a quarry site located in Ijebu North local government area of Ogun State, Nigeria. The physicochemical properties were determined using standard methods, and metal quantification was done using Inductively Coupled Optical Emission Spectrometry (ICP-OES). The results of physicochemical properties of the sampled soil include: pH (7.20–8.74), bulk density (0.922–1.198 g/cm³), and moisture content (26.3–34.1%). Turbidity is 56.3 higher than the WHO standard, while alkalinity is 144. The physicochemical properties of the water samples all fall within the permissible limits set by the WHO except for alkalinity, turbidity, hardness, suspended solids, and COD. The results of metal analysis (mg/kg) are as follows: ≤9.94, ≤ 3961.77, ≤ 11.07, ≤ 244.03, ≤ 111.77, ≤ 251.19, ≤ 262.84, ≤ 101.23, ≤ 3094.87, ≤ 2816.07, ≤ 235.78, ≤ 182.72 for Ag, Al, As, B, Ba, Cd, Co, Cr, Cu, Fe, Mn, Ni, and Pb, respectively, in all the environmental samples. High levels above the WHO permissible standard of toxic metals under study were found in rock samples, and these are statistically similar to the levels recorded in soil samples close to the quarry site. Additionally, high levels of Al, Cd, Cr, Cu, Fe, and Mn above the WHO limit were recorded in plant and water samples close to the quarry site. Quarry activities in the study site have a negative impact on the soil, plant, and water body around the site, and this needs to be checked on time before it degenerates into an environmental catastrophe.
The introduction of video-enabled directly observed therapy (video-DOT) for patients with drug-resistant TB disease in Eswatini amid the COVID-19 pandemic – a retrospective cohort study
Authors: Kerschberger Bernhard , Daka Michelle , Shongwe Bhekiwe , Dlamini Themba , Ngwenya Siphiwe , Danbakli Clara , Mamba Bheki , Nxumalo Bongekile , Sibanda Joyce , Dube Sisi , Dlam Lindiwe Mdluli , Mabhena Edwin , Mukooza Esther , Crumley Iona , Ciglenecki Iza , Vambe Debrah 
Published: August 2023

Abstract
Background
Video-enabled directly observed therapy (video-DOT) has been proposed as an additional option for treatment provision besides in-person DOT for patients with drug-resistant TB (DRTB) disease. However, evidence and implementation experience mainly originate from well-resourced contexts. This study describes the operationalization of video-DOT in a low-resourced setting in Eswatini facing a high burden of HIV and TB amid the emergence of the COVID-19 pandemic. Methods
This is a retrospectively established cohort of patients receiving DRTB treatment during the implementation of video-DOT in Shiselweni from May 2020 to March 2022. We described intervention uptake (vs in-person DOT) and assessed unfavorable DRTB treatment outcome (death, loss to care) using Kaplan-Meier statistics and multivariable Cox-regression models. Video-related statistics were described with frequencies and medians. We calculated the fraction of expected doses observed (FEDO) under video-DOT and assessed associations with missed video uploads using multivariable Poisson regression analysis.
Results
Of 71 DRTB patients eligible for video-DOT, the median age was 39 (IQR 30–54) years, 31.0% (n=22) were women, 67.1% (n=47/70) were HIV-positive, and 42.3% (n=30) were already receiving DRTB treatment when video-DOT became available. About half of the patients (n=37; 52.1%) chose video-DOT, mostly during the time when COVID-19 appeared in Eswatini. Video-DOT initiations were lower in new DRTB patients (aHR 0.24, 95% CI 0.12–0.48) and those aged ≥60 years (aHR 0.27, 95% CI 0.08–0.89). Overall, 20,634 videos were uploaded with a median number of 553 (IQR 309–748) videos per patient and a median FEDO of 92% (IQR 84–97%). Patients aged ≥60 years were less likely to miss video uploads (aIRR 0.07, 95% CI 0.01–0.51). The cumulative Kaplan-Meier estimate of an unfavorable treatment outcome among all patients was 0.08 (95% CI 0.03–0.19), with no differences detected by DOT approach and other baseline factors in multivariable analysis.
Conclusions
Implementing video-DOT for monitoring of DRTB care provision amid the intersection of the HIV and COVID-19 pandemics seemed feasible. Digital health technologies provide additional options for patients to choose their preferred way to support treatment taking, thus possibly increasing patient-centered health care while sustaining favorable treatment outcomes.
Evaluation of tornado loads on double-sloped roofs at various ground roughness and positions by numerical Ward-type tornado simulation
Authors: Yuan Zhongya , Wang Xueyan , Jia Yanzhen , Cao Wenlong , Yang Jian , An Jianhui 
Published: August 2023

Abstract
The effect of various slope angles, ground roughness and positions on tornado loading characteristics of double-sloped roof is identified through Ward-type tornado numerical simulation. Tornado fields under multiple operating conditions are established through a numerical Ward-type tornado generation apparatus and the reliability is verified by comparing simulation results with experimental data. A comparison of wind pressure distribution for double-sloped roofs with four different angles is used to determine the most unfavourable roof conditions for a tornado field. The wind pressure characteristics of double-sloped roofs at different locations in a tornado field is examined by comparing the wind pressure coefficients at five different locations on smooth and rough ground. Calculations of wind pressure coefficients for five ground roughness are carried out to identify the effect of different ground roughness on wind pressure distribution in roofs. Vortex volumes at different locations are calculated and analyzed to further verify the relationship between the wind pressure characteristics at different locations. This study sheds light on tornado loads on double-sloped roofs at various ground roughness and positions, and helps to clarify the mechanical properties, unfavourable locations and wind resistance design of double-sloped roofs under tornado action.
Bionanocomposite MIL-100(Fe)/Cellulose as a high-performance adsorbent for adsorption of methylene blue
Authors: Abbasi Shahla , Nezafat Zahra , Javanshir Shahrzad , Aghabarari Behzad 
Published: August 2023

Abstract

Water refining treatment consisted to eliminate organic matter and improve the organoleptic qualities of the water (flavor, smell, clarity). There are different methods for removal of pollutants which among them, the adsorption process has been expanded due to its easiness and high efficiency. The development of innovative porous materials is therefore of primary importance for the treatment of effluents. Dyes are important source of pollution once discharged into the environment. World production of dyes is estimated at more than 800,000 t•yr− 1. The purpose of this research falls within the scope of the choice of an effective, local and inexpensive adsorbent to remove dyes from waste water. Adsorptive elimination of dyes by commonly accessible adsorbents is inefficient. The metal organic frameworks (MOFs) are important class of porous materials offering exceptional properties as adsorbents by improving separation efficiency compared to existing commercial adsorbents. However, its powder form limits its applications. One way to overcome this problem is to trap them in a flexible matrix to form a hierarchical porous composite. Therefore, in this work, we prepared MIL-100 (Fe) embedded in cellulose matrix named MIL-100(Fe)/Cell, and used it as an adsorbent of methylene blue (MB) dye. Adsorption was studied as a function of contact time, adsorbent mass and pollutant load (concentration), and pH, and the effect of each of them on absorption efficiency was optimized. MIL-100(Fe)/Cell was capable to remove 98.94% of MB dye with an initial concentration of 150 mg/L within 10 minutes. The obtained maximum adsorption capacity was 384.615 mg/g. The adsorption isotherm and kinetic were consistent with the Langmuir and pseudo-second order models. The mechanism of MB adsorption proceeds through п-п and electrostatic interactions.
Outcomes with hybrid catheter-directed therapy compared with aspiration thrombectomy for patients with intermediate-high risk pulmonary embolism
Authors: Sławek-Szmyt Sylwia , Araszkiewicz Aleksander , Jankiewicz Stanisław , Grygier Marek , Mularek-Kubzdela Tatiana , Lesiak Maciej 
Published: August 2023

Abstract
Purpose
Intermediate-high-risk pulmonary embolism (IHR PE) is a challenging form of embolism obstruction that causes right ventricular dysfunction. The optimal management of IHR PE has not been established. This single-center prospective, observational study aimed to evaluate the efficacy and safety of hybrid therapy (CDT)- catheter-directed mechanical aspiration thrombectomy (CDMT) in comparison to CDMT supplemented with catheter-directed thrombolysis (hybrid CDT) for IHR PE.
Methods
A propensity score based on Pulmonary Embolism Severity Index class and Miller Obstruction Index (MOI) was calculated, and 21 hybrid CDT cases (mean age 54.8 (14.7) years, 9/21 women) were matched with 21 CDMT cases (mean age 58.8 [14.9] years, 13/21 women). The baseline demographics and clinical and treatment characteristics were analyzed.
Results
No significant differences were detected regarding baseline demographics and PE severity parameters. Hybrid CDT demonstrated a higher reduction in mean pulmonary artery pressure (mPAP) (hybrid CDT: median mPAP reduction 8 mmHg [IQR: 6–10 mmHg] vs CDMT: median mPAP reduction 6 mmHg [IQR: 4–7 mmHg; P = 0.019), MOI score (hybrid CDT: median change − 5 points [IQR:5–6 points] vs CDMT median change − 3 points [IQR:3–5 points]; P = 0.019), and median RV: Left ventricular ratio (hybrid CDT: median change 0.4 [IQR:0.3–0.45] vs CDMT median change 0.26 [IQR:0.2–0.4]); P = 0.007). No major bleeding was observed. Both the hybrid CDT and CDMT alone treatments are safe and effective in managing IHR PE.
Conclusions
Hybrid CDT is a promising technique for the management of IHR PE with insufficient thrombus load reduction by CDMT.
Trial registration number:
NCT0447356 – registration date 16 July 2020
Mindflow in crisis: the mediating role of psychological capital and coping competence between mindfulness and flow during COVID-19.
Authors: Rahnama Nargess , Malekzadeh Gholamreza , Moshtari Mohammad 
Published: August 2023

Abstract
Background
The present study aims to investigate whether and how mindfulness leads to the flow experience in high-pressure situations during the coronavirus pandemic peak, especially in high-risk, challenging contexts such as emergencies. therefore, the authors aim to expand existing knowledge about experiencing flow at work, specifically in the crisis context of the COVID-19 period, when challenges convert to hindrance demands. Before examining the possible processes and mechanisms in this relationship, we examined the mediating role of two variables: psychological capital and coping competence.
Method
The statistical population of this study consists of all employees of emergency centers in Mashhad, Iran; there were 550 at the time of the study. Using a simple random sampling method and the Morgan table, a sample of 220 people was considered. A structural equation model, AMOS, and SPSS software were used to analyze the collected data.
Result
The results emphasize that among employees who experienced mindfulness, an optimal experience did not necessarily occur, specifically in those situations in which challenge stressors become hindrance stressors. Although the association of mindfulness and coping competence was verified, its association with flow through coping competence was rejected. It is verified that mindfulness would be associated with flow through psychological capital.
Conclusion
The study extends our understanding of occurring flow at high-risk work environments in which challenges are not motivational. The authors studied the experience of flow in a work context with challenges that appear in the form of hindrance demands, different from the previous ones that have studied flow experience in challenging and motivating contexts such as sports contexts, including mountain climbing, surfing, and similar cases. In addition, there was no consensus in different past studies about associating mindfulness with flow experience. Therefore, in this case, further study had been left to future studies. Moreover, the process of this relationship through the mediating role of psychological capital and coping competence has not been investigated in previous studies.
A bridge between infertility and anxiety: a novel role for genes
Authors: Bausyte Raminta , Mazeikiene Brigita Vaigauskaite - , Skliute Giedre , Valatkaite Elvina , Sabaityte Evelina , Kazenaite Edita , Ramasauskaite Diana , Navakauskiene Ruta 
Published: August 2023

Abstract
Background. Infertility can negatively affect mental health. Conversely, it is also hypothesized that psychological imbalance may exert a damaging influence on reproductive function. Unfortunately, until now it has been difficult to objectively explain these relations. Certain researchers suggest that genetic and epigenetic mechanisms could be factors. The aim of this study was to investigate the connection between infertility, anxiety and (or) depression by examining underlying genetics, so we can formulate future perspectives.
Methods. The present study was conducted in few stages: (a) psychological assessment of females undergoing assisted reproductive technology (ART) procedure due to couple infertility, using the Hospital Anxiety and Depression Scale (HADS); (b) collection of endometrial samples before ART cycle from study participants; (c) isolation and cultivation of human endometrial-derived mesenchymal stromal cells (EnSCs); (d) analysis of 26 EnSCs’ genes by the reverse transcription-quantitative polymerase chain reaction (RT-qPCR): cell cycle regulation related (SLC39A1, RBM6, BLCAP, GATAD2B, RNF123, RECQL4), immune response related (AFF3, CD58, TNFSF4), signal transduction related (ESR1, CRTC2, CXCL8, PPP1R16A, NDN, GRB10, HTR2A, RB1, NR3C1, AXL), cell differentiation related (PAX8AS1, H19, EFNA5, IGF2), secretion related genes (MON1A, CYR61) and embryogenesis related genes (TFPI2); (e) statistical analysis; (f) summarization.
Results. We investigated 32 females. 12 females expressed considerable symptoms of anxiety and 1 female showed symptoms of depression. 19 females conceived after ART procedures. Genetic analysis showed tendentious alterations in certain cell cycle regulation and transcription/translation, immune response, signal transduction, cell differentiation, secretion and embryogenesis process related gene expression according to female expression of anxiety. Moreover, it was observed that certain mechanisms could adversely affect pregnancy outcome after ART cycle or at least reflect it.
Conclusions. It is known that infertility can have a harmful impact on a person’s psychology. However, a perception can be made that some tendencies such as anxiety may affect fertility even through the gene profile. The results we obtained encourage a deeper exploration of the relationship between fertility disorders, psychology and genes, as it does seem that qualified and timely psychological assessment, counselling and support could be one of the keys to raising pregnancy rates among infertile couples.
Mesenchymal Stem Cells Lose the Senescent Phenotype Under 3D Cultivation
Authors: Krasnova Olga , Kovaleva Anastasiia , Saveleva Arina , Kulakova Karina , Bystrova Olga , Martynova Marina , Domnina Alisa , Neganova Irina 
Published: August 2023

Abstract

Background Three-dimensional (3D) cell culture is widely used in various fields of cell biology. In comparison to conventional two-dimensional (2D) cell culture, 3D cell culture facilitates a more accurate replication of thein vivomicroenvironment, which is essential for obtaining more relevant results. The application of 3D cell culture techniques in regenerative medicine, particularly in mesenchymal stem cell (MSC)-based research, has been extensively studied. Many of these studies focus on the enhanced paracrine activity of MSCs cultured in 3D environments. However, few focus on the cellular processes that occur during 3D cultivation. Methods In this study, we studied the changes occurring within 3D-cultured MSCs (3D-MSCs). Specifically, we examined the expression of numerous senescent-associated markers, the actin cytoskeleton structure, the architecture of the Golgi apparatus and the localization of mTOR, one of the main positive regulators of replicative senescence. In addition, we assessed whether the selective elimination of senescent cells occurs upon 3D culturing by using cell sorting based on autofluorescence. Results Our findings indicate that 3D-MSCs were able to overcome replicative senescence. We discovered changes in actin cytoskeleton structure, Golgi apparatus architecture and revealed that 3D cultivation leads to the nuclear localization of mTOR, resulting in a decrease in its active cytoplasmic form. Furthermore, we confirmed that 3D cell culture facilitates the rejuvenation of senescent cells rather than their elimination from the bulk population. Conclusion These novel insights into the biology of 3D-MSCs can be applied to research in regenerative medicine to overcome replicative senescence and MSC heterogeneity as they often pose significant concerns regarding safety and effectiveness for therapeutic purposes.
Serum metabolome analysis in hyperthyroid cats before and after radioactive iodine therapy
Authors: Bechtold Molly A. , Lin Yimei , Miller Meredith L. , Prieto Jennifer M. , Frederick Carol E. , Bennett Lucinda L. , Peterson Mark E. , Simpson Kenneth W. , Loftus John P. 
Published: August 2023

Abstract

Hyperthyroidism is the most common feline endocrinopathy. In hyperthyroid humans, untargeted metabolomic analysis identified persistent metabolic derangements despite achieving a euthyroid state. Therefore, we sought to define the metabolome of hyperthyroid cats and identify ongoing metabolic changes after treatment. We prospectively compared privately-owned hyperthyroid cats (n = 7) admitted for radioactive iodine (I-131) treatment and euthyroid privately-owned control (CON) cats (n = 12). Serum samples were collected before (T0), 1-month (T1), and three months after (T3) I-131 therapy for untargeted metabolomic analysis by MS/MS. Hyperthyroid cats (T0) had a distinct metabolic signature with 277 significantly different metabolites than controls (70 increased, 207 decreased). After treatment, 66 (T1 vs. CON) and 64 (T3 vs. CON) metabolite differences persisted. Clustering and data reduction analysis revealed separate clustering of hyperthyroid (T0) and CON cats with intermediate phenotypes after treatment (T1 & T3). Mevalonate/mevalonolactone and creatine phosphate were candidate biomarkers with excellent discrimination between hyperthyroid and healthy cats. We found several metabolic derangements (e.g., decreased carnitine and a-tocopherol) do not entirely resolve after achieving a euthyroid state after treating hyperthyroid cats with I-131. Further investigation is warranted to determine diagnostic and therapeutic implications for candidate biomarkers and persistent metabolic abnormalities.
Federated Learning: Healthcare, Security, Challenges, and Threats
Authors: N Sumanth , Heggere Shalini B , E Prathiksha , Shetty Chintan Ashok , H Nikhitha H R , C Soundarya B 
Published: August 2023

Abstract

Over the last four years, machine learning has undergone a significant shift due to concerns over privacy and the desire for deep learning. New methods of implementing machine learning, such as federated learning (FL), are replacing centralized systems and on-site analysis. FL is a decentralized approach that safeguards privacy by storing raw data on devices and using local machine learning to reduce communication costs. A central server collects and distributes shared models and knowledge among participants. Before delving into FL, this essay compares and contrasts various ML-based deployment strategies.
This paper presents a unique classification of FL challenges and research areas, unlike previous analyses in the field. It is based on a thorough analysis of key technological roadblocks and current activities, and covers intricate subjects, contributions, and trends in the literature. The taxonomies encompass fundamental system models and designs, application domains, privacy and security, and resource management. Additionally, this paper discusses significant difficulties.
Change of Direction and Linear Speed Relation to Functional Ability and Joint Mobility in Polish Women’s Volleyball and Basketball 3x3 National Teams
Authors: Czyżnielewska Zuzanna , Yagin Fatma Hilal , Gabryś Tomasz , Cepicka Ladislav 
Published: August 2023

Abstract

The purpose of this study was to determine the relationship between sprint, COD, CODD and functional status in polish women’s national teams: volleyball and basketball 3x3. A total of 23 athletes: 12 volleyball players (age:18 ± 0years; body height:183 ± 7cm; body weight:70 ± 8kg) and 11 basketball players (age:26 ± 4 years; body height:180 ± 6cm; body weight:73 ± 10kg) participated in the study. Athletes were tested for the following measures: FMS test, Y-Balance test, joints range of motion measurements, maximal sprint test (14m) and modified COD test (14m). COD deficit was calculated by subtracting COD speed time from sprint speed time. A value of p < 0.05 was considered statistically significant. There was no significant correlation between sprint and CODD results in basketball team. In volleyball team there was a positive and significant correlation between COD, sprint and CODD. There was a negative and significant correlation between Y-Balance scores and sprint test results in the basketball team. Basketball team had a positive significant correlation between hip rotations and COD results. Volleyball team results of the upper back rotations and sprint test were found to have a negative significant correlation. There was a negative significant correlation between shoulder movements and COD and CODD results in volleyball team.