bluuebunny/crossref_metadata_2025_split huggingface dataset:
A selective inhibitor of the sperm-specific potassium channel SLO3 impairs human sperm function
Authors: Lyon Maximilian , Li Ping , Ferreira Juan J. , Lazarenko Roman M. , Kharade Sujay V. , Kramer Meghan , McClenahan Samantha J. , Days Emily , Bauer Joshua A. , Spitznagel Brittany D. , Weaver C. David , Borrego Alvarez Aluet , Puga Molina Lis C. , Lybaert Pascale , Khambekar Saayli , Liu Alicia , Lindsley Craig W. , Denton Jerod , Santi Celia M. 
Published: January 2023

To fertilize an oocyte, the membrane potential of both mouse and human sperm must hyperpolarize (become more negative inside). Determining the molecular mechanisms underlying this hyperpolarization is vital for developing new contraceptive methods and detecting causes of idiopathic male infertility. In mouse sperm, hyperpolarization is caused by activation of the sperm-specific potassium (K+) channel SLO3 [C. M. Santi et al., FEBS Lett.584, 1041–1046 (2010)]. In human sperm, it has long been unclear whether hyperpolarization depends on SLO3 or the ubiquitous K+channel SLO1 [N. Mannowetz, N. M. Naidoo, S. A. S. Choo, J. F. Smith, P. V. Lishko,Elife 2, e01009 (2013), C. Brenker et al., Elife3, e01438 (2014), and S. A. Mansell, S. J. Publicover, C. L. R. Barratt, S. M. Wilson, Mol. Hum. Reprod.20, 392–408 (2014)]. In this work, we identified the first selective inhibitor for human SLO3—VU0546110—and showed that it completely blocked heterologous SLO3 currents and endogenous K+currents in human sperm. This compound also prevented sperm from hyperpolarizing and undergoing hyperactivated motility and induced acrosome reaction, which are necessary to fertilize an egg. We conclude that SLO3 is the sole K+channel responsible for hyperpolarization and significantly contributes to the fertilizing ability of human sperm. Moreover, SLO3 is a good candidate for contraceptive development, and mutation of this gene is a possible cause of idiopathic male infertility.
“Let’s … together”
Authors: Sun Xiaochun , Chen Xinren 
Published: January 2023

Abstract
This study, drawing on a modified version of Spencer-Oatey’s Rapport Management Model (2008), attempts to probe into the underexplored phenomenon of apparent rapport management in Chinese directive public signs in terms of face, sociality rights and obligations, interests, and interactional goals. Based on the analysis of data collected from four cities in China, this study demonstrates how some Chinese producers of directive public signs make varying and various discursive efforts to enhance rapport with the general public. It is argued that this “personalization” characteristic of Chinese directive public signs suggests their producers’ attempt at doing rapport with the public. This research, while extending the scope of discussion on rapport management from the interpersonal to the public sphere, might serve to explain why some Chinese directive public signs (directives in particular) are not terse.
A cross-linguistic syntactic analysis of telicity in motion predicates in Southern Tati, Mandarin, and Ghanaian Student Pidgin
Authors: Chen Pin-Hsi Patrick , Osei-Tutu Kwaku Owusu Afriyie , Taherkhani Neda 
Published: January 2023

AbstractThis paper proposes an analysis of telicity in motion predicates within the framework of the Exo-Skeletal Model (Borer 2005b). We hypothesize that a motion event is syntactically represented by a Path component, the core of which is avP that introduces a Figure argument. This Path component is interpreted as quantity in the sense ofBorer (2005b)when there is a certain type of morpheme present in the structure, such as a verb that denotes the reaching of an endpoint. A quantity Path component can then assign a semantic value to a functional projection called AspQP, which returns a telic interpretation. Data from Mandarin, Ghanaian Student Pidgin, and Southern Tati show AspQP can be assigned a value either with or without overt head movement. We further propose a distinction between Path and direction, which explains data that were left unexplained in previous studies and seemingly contradict our claim.
Mouldy Planet: Fungi and One Health
Authors: Ogunseitan Oladele A. , Matlock Melissa 
Published: January 2023

Summary
Prevention of diseases caused by pathogenic fungi exemplifies the need for a One Health approach because a fungal species can cause similar disease in humans and animals and can survive long in the environment. This case study of coccidioidomycosis (valley fever) illustrates the power of integrative surveillance for One Health.

Fungi belong to a taxonomically distinctive group of organisms that are among the most diverse, widely distributed and metabolically versatile organisms on earth. Physically, fungi range in size from microscopic yeasts, visible mould with colourful spores, and mushrooms, which may be larger than a human palm. Through their genetic profile and heterotrophy, fungi are more related to animals than to plants. Fungi can cause disease in humans, animals and plants, and they produce infectious forms such as lightweight spores, which can survive long in natural environments. Therefore, many diseases caused by pathogenic fungi are better understood and controlled through a transdisciplinary One Health approach. Fungi produce antibiotics such as penicillin, and they are also capable of developing resistance to many medications used to treat infections, making them a major threat to global health. This case study focuses on coccidioidomycosis (valley fever), an illness that develops from inhaling spores of the fungus
Coccidioides imitis
or
Coccidioides posadasii
, which are commonly found in soils of the south-western USA and in Central and South America, where the disease has been long recognized as a threat. Communities of people, pets and farm animals inhabiting periodically dry environmental conditions are particularly vulnerable, and investigators have suggested that the current incidence of the disease and the geographical expansion of zones of vulnerability are linked to climate change.

1

Improved understanding of the One Health context of valley fever should inform public communication strategies for preventing the disease.
Self-consistent treatment of gas heating in modeling of a coaxial DBD in atmospheric pressure CO2
Authors: Zhou Chen , Yuan Chengxun , Kudryavtsev Anatoly , Yasar Katircioglu T , Rafatov Ismail , Yao Jingfeng 
Published: January 2023

Abstract
This work is devoted to the numerical study of characteristics of dielectric barrier discharge maintained in a coaxial reactor in atmospheric pressure

C

O
2

. The numerical model is based on the drift-diffusion theory of gas discharges, and takes into account the gas heating in a self-consistent manner. The effect of incorporating gas heating into the discharge properties, specifically, on

C

O
2

decomposition, is investigated for wide range of amplitude and frequency of the applied voltage. Calculations revealed a significant effect of gas heating on

C

O
2

conversion. Calculations with a constant (room) gas temperature led to a strong overestimation of

C

O
2

conversion level.
Vertical and lateral random vibration of high-temperature superconductor maglev under high-speed operation conditions
Authors: Huang Zhichuan , Hong Ye , Ke Zhihao , Liu Jianxin , Deng Zigang 
Published: January 2023

Abstract
High-temperature superconductor (HTS) maglev systems shows significant potential to be applied to high-speed rail transportation based on its passive stable levitation owing to the coupling between the HTS bulks and permanent magnetic guideway (PMG). As one of the key factors to guarantee the safe and stable operation of HTS maglev, the dynamic characteristics of the HTS bulks reflecting the operational performance of the HTS maglev system under high-speed running conditions should be focused on. Therefore, this paper, based on H-formulation, established a finite element model of an HTS-PMG system, and assessed its feasibility by experiments. Moreover, the random free vibration of the HTS bulk caused by guideway random irregularity at high speed is also studied by this validated model. The random vibration characteristics and temperature variation of the HTS bulk at three high speeds (600 km h−1, 800 km h−1, and 1000 km h−1) under vertical vibration, lateral vibration, and vertical-lateral coupling vibration, respectively, are compared. The results show that at high speed, vertical vibration can only cause the fluctuation of levitation height, while lateral vibration and vertical-lateral coupled vibration will affect both lateral offset and levitation height. Compared with the mere vertical or lateral vibration mode, the levitation height attenuation and temperature rise of the coupling vibration mode is greater due to more energy loss caused by magnetic flux motion, but it can aid in the suppression of the vibration in the vertical and lateral directions. The increase of velocity intensifies the vibration strength of the HTS bulk and increases the fluctuation of the levitation height, lateral offset, and temperature rise. However, vibrations at a certain high speed causes a limited temperature rise and thus a limited influence on the bulk performance, and the HTS bulk is still in the safe operating range at a maximum speed of 1000 km h−1. These conclusions are anticipated to provide some references for future high-speed applications of the HTS maglev system.
Role of the scalar

in the process

*
Authors: Zhang Han , Lyu Yun-He , Liu Li-Juan , Wang En 
Published: January 2023

Abstract
Based on BESIII measurements of the reaction

, we investigate this process by considering the S-wave pseudoscalar-pseudoscalar interaction within the unitary chiral approach and the contributions from the intermediate resonances

and

. Our calculation can reasonably reproduce the experimental data, and our results imply that

, which is dynamically generated from the S-wave pseudoscalar-pseudoscalar interaction, plays an important role in this process, and the contributions from the intermediate resonances

and

are also necessary. More precise measurements of this process in future can shed light on the nature of

and

.
A 64 channels ASIC for the readout of the silicon strip detectors of the PANDA micro-vertex detector
Authors: Mazza G. , Calvo D. , Cossio F. , De Remigis P. , Mignone M. , Wheadon R. , Silvestrin L. , Tessaro M. 
Published: January 2023

Abstract
The ToASt ASIC is a 64 channel integrated circuit designed for the readout of the double-sided silicon strip sensors that will equip the micro-vertex detector of the PANDA experiment. The ToASt ASIC operates with a 160 MHz clock, which defines also the time resolution. A common time stamp is distributed to all channels to provide a common time reference for time of arrival and time over threshold measurements. Two 160 Mb/s serial lines provide the interface to the data concentrator. ToASt is implemented in a commercial 110 nm CMOS technology with triplicated logic to protect against single event upsets.
Intensified Tpx3Cam, a fast data-driven optical camera with nanosecond timing resolution for single photon detection in quantum applications
Authors: Nomerotski A. , Chekhlov M. , Dolzhenko D. , Glazenborg R. , Farella B. , Keach M. , Mahon R. , Orlov D. , Svihra P. 
Published: January 2023

Abstract
We describe a fast data-driven optical camera, Tpx3Cam, with nanosecond scale timing resolution and 80 Mpixel/sec throughput. After the addition of intensifier, the camera is single photon sensitive with quantum efficiency determined primarily by the intensifier photocathode. The single photon performance of the camera was characterized with results on the gain, timing resolution and afterpulsing reported here. The intensified camera was successfully used for measurements in a variety of applications including quantum applications. As an example of such application, which requires simultaneous detection of multiple photons, we describe registration of photon pairs from the spontaneous parametric down-conversion source in a spectrometer. We measured the photon wavelength and timing with respective precisions of 0.15 nm and 3 ns, and also demonstrated that the two photons are anti-correlated in energy.
DART28-FPGA implementation study for future high-speed links
Authors: Wanotayaroj C. , Mendes E. , Baron S. , Kulis S. 
Published: January 2023

Abstract
The data link from the detectors to the back-end stage must keep up with the requirements from the upcoming generation of High Energy Physics experiments. Last year, we presented at TWEPP the investigation on the feasibility and limitation of high data-rate links based on the 4-Level Pulse-Amplitude Modulation (PAM4) technology. Commercial PAM4 technology poses strict constraints on the data rate of links which translates into a highly complex rad-hard SerDes design. Alternatively, pushing the limit of the Non-Return to Zero (NRZ) modulated signals, a line rate of up to 28 Gbps can be realized. This is less constraining thanks to the possibility of bypassing retimers of NRZ modules. As a part of the Work Package 6 of the CERN EP Research and Development programme, the feasibility as well as the availability in the telecom and datacom market of such NRZ links have been investigated. The rate of 25.65 Gbps per lane (an integer multiplication of the 40.0798 MHz Bunch Clock) with NRZ modulation have been identified as the target for the next generation of detector-to-backend links. The Demonstrator ASIC for Radiation-Tolerant Transmitter in 28 nm (DART28) chip, designed at 28 nm and targeting high-radiation hardness, is currently being designed at this data rate with a custom protocol and a Reed-Solomon Forward Error Correction (FEC). A proof-of-concept on FPGA emulating the DART28 protocol has been built for early evaluation. The system uses commercially available optoelectronics transceivers and FPGA platforms to implement the DART28 data path containing a scrambler, interleaver and FEC. The VCU129 Xilinx Virtex Ultrascale+ and Intel Stratix 10 evaluation boards were used for this work. In this paper, the implementation of the demonstrator systems will be presented. The performance characteristic of these links will be discussed and the FEC performance will be compared to that of an ideal model.
Prototyping serial powering for the ATLAS ITk pixel detector
Authors: Senger T. 
Published: January 2023

Abstract
The high luminosity upgrade for the LHC at CERN requires a complete overhaul of the current inner detectors of ATLAS and CMS. A serial powering scheme has been chosen to cope with the constraints of the new pixel detectors. A prototype stave consisting of up to 8 quad modules, based on the new readout chips developed by the RD53 collaboration in 65 nm CMOS technology, RD53A and ITkPixV1, has been set up in Bonn. This contribution covers the results obtained with RD53A modules and presents first measurements with a full ITkPixV1.1 serial powering chain.
The CMS pixel detector for the High Luminosity LHC
Authors: Cassese A. 
Published: January 2023

Abstract
The LHC machine will be upgraded to increase its peak luminosity to 5–7.5 × 1034 cm−2 s−1 and to possibly reach an integrated luminosity of 3000–4000 fb−1, with an average number of pileup events of 140–200. The CMS experiment needs to be upgraded to keep up with the new challenges: the unprecedented radiation environment translates to the detector requirement of high resilience, while the increased number of events per bunch crossing requires higher detector granularity. Thus a completely new Inner Tracker will be installed. Design choices for the Inner Tracker Phase-2 upgrade, highlighting R&D activities and technological approaches, will be presented.
Detector design and performance tests of the ESS-neutron Beam Loss Monitor detectors
Authors: Segui L. , Dolenc Kittelmann I. , Papaevangelou T. , Aune S. , Benedetti F. , Gougnaud F. , Lahonde C. , Legou P. , Mariette Y. , Marroncle J. , Mikulec B. , Nadot V. , Tsiledakis G. , Shea T.J. , Zamantzas C. 
Published: January 2023

Abstract
A new type of beam loss monitor has been developed based on
the detection of fast neutrons produced by beam losses in hadron
linear accelerators. This neutron sensitive Beam Loss Monitor (nBLM)
has been concieved to fulfil the requirements of the European
Spallation Source (ESS) and it will be part of the ESS neutron
sensitive BLM system (ESS-nBLM). It has been specifically designed
for the low energy part, where only neutrons and gammas produced by
the loss can exit the accelerator vessel. Here other types of BLM,
based on charged particle detection, suffer from the lack of signal
compared to the photon background induced by the radio-frequency
cavities. However, it can also be operated in regions of higher
energy. The detector is of the Micromegas type and have been
designed at IRFU to be able to detect fast neutrons while having a
small sensitivity to gammas and thermal neutrons. In this work we
focus on the proof of neutron-to-gamma rejection and the first
operation of the detector in real beam conditions during the
commissioning of LINAC4 (CERN). Controlled beam losses were provoked
and have been detected by the nBLM detector installed, demonstrating
also the discrimination of the neutron signal from RF x-ray
background.
Technological diffusion trends suggest a more equitable future for rooftop solar in the United States
Authors: O’Shaughnessy Eric , Kim James Hyungkwan , Darghouth Naïm 
Published: January 2023

Abstract
Equity has become central in the academic and regulatory discourse shaping the future of residential-scale clean energy technologies in the United States, particularly rooftop solar. Here, we develop a holistic perspective on these issues by analyzing rooftop solar adoption trends using two alternative forecasting methods: an inside-view forecast based on historical solar adoption data, and an outside-view forecast based on adoption data for other emerging consumer technologies. We show how rooftop solar, like other emerging consumer technologies, has become more equitably adopted over time. We show that solar diffusion patterns are largely consistent with those of other technologies. Both forecasting methods suggest that clean energy technologies should be expected to become more equitably adopted over time. Policy could accelerate this process by supporting low-income adoption without unduly curbing overall diffusion.
Different mechanisms for the extremely hot central-eastern China in July–August 2022 from a Eurasian large-scale circulation perspective
Authors: Wang Ziqian , Luo Haolin , Yang Song 
Published: January 2023

Abstract
In July and August of 2022, unprecedented and long-lasting heatwaves attacked central and eastern China (CEC); and the most affected area was in the Yangtze River (YR) basin. The extreme heatwaves and associated drought and wildfire had significant social impacts, but the underlying mechanisms remain unknown. Observational analysis indicates that the heatwaves were regulated by anomalous anticyclone in the mid-upper troposphere over northern CEC. Specifically, the easterly anomalies at the southern flank of the anticyclone caused air isentropic sliding and transported low moist enthalpy (cold and dry) air to the YR basin, contributing to anomalous sinking motions and extreme heatwaves. In comparison, heatwaves were more serious in August than in July due to stronger upper-level anomalous anticyclone and associated easterlies. Importantly, different mechanisms were responsible for the heatwaves in the two months. In July, the relatively weaker anticyclonic anomaly over northern CEC was dominated by the forcing of diabatic heating over northwestern South Asia (NWSA), corresponding with the record-breaking rainfall in and around Pakistan. In August, a powerful anticyclonic condition for the CEC heatwaves originated from an extreme silk road pattern (SRP), superposing the effect of NWSA diabatic heating due to persistent downpour. We notice that another upstream anticyclonic node in the SRP also created heatwaves in Europe. Therefore, the CEC extreme heat was actually associated with other concurrent extremes over the Eurasian continent through large-scale atmospheric teleconnections in 2022.
Green Energy Potential in University Building’s Roofs, Assessed Through the Possibility for Installation of Commercial Photovoltaic Systems
Authors: Beloev H. I. , Iliev I. K. , Ilieva D. I. , Terziev A. K. , Ivanov M. 
Published: January 2023

Abstract
The presented paper reveals the analyses of green energy potential in university building’s roofs, assessed through the possibility of the installation of commercial photovoltaic systems. The studied roofs are part of the existing buildings of the University of Ruse “Angel Kanchev”, Bulgaria. Extensive electricity consumption and production analyses are made, based on recent accounting, measurements, and forecasted data. The estimated production of electricity from the proposed photovoltaic plant on the roofs of buildings 2, 9, 10 and UPZ of RU “Angel Kanchev”, is in the amount of 1 212 MWh/year, which constitutes 68.2% of the electricity consumed in 2019. The proposed measures will lead to the estimated 992.63 tons/year of CO2 emissions saved, and the annual CO2 emissions of RU “Angel Kanchev” will be reduced by 68.3%.
Numerical verification of the calorimeter concept for determining the calorific value of unidentified gaseous fuels
Authors: Markowski J , Imiłkowski P , Netter K , Jesionek K , Mądry J , Wieczorkiewicz G 
Published: January 2023

Abstract
Measurement of the calorific value of fuels with the use of the present calorimeter structures requires specific conditions and takes a relatively long time. These requirements are related to the assurance of appropriate environmental parameters, i.e. temperature, air humidity in the room within a narrow range of variability, which means there is a need to require ensuring laboratory conditions for the measurement. This situation is closely related to the complicated measurement methodology. Therefore, taking into account these problems, the market need has been defined resulting from the specificity of the operation of industrial installations, in which it is important to evaluate the quality of the consumed or produced gaseous fuel. This article presents an innovative concept of a calorimeter designed to determine the calorific value of gaseous fuels, and also describes a mathematical model of the device made in the SciLab environment, which is the basis for further considerations.