bluuebunny/crossref_metadata_2025_split huggingface dataset:
Differences in the Seoi-Nage Skill between Elite and Non-Elite Judo Athlete’s
Authors: Choi Sang-Hyup , Song Yong-Gwan 
Published: January 2023

Abstract
Background
The present study examined the effects of the seoi-nage skill using expert (i.e., elite) and novice (i.e., non-elite) judo athletes.
Methods
Ten with expert judo athletes and 10 novice judo athletes were instructed to perform seoi-nage skill that consist of three phases (i.e., unbalancing, positioning, and throwing). Kinematic characteristics of the three phases data was collected from an optical motion capture 3D camera, and used to measure the magnitude and direction of the force.
Results
The results indicated that the expert judo athletes showed better performance the rotation and tilt angle characteristics of the shoulder and pelvis, and hip and knee joint flexion-extension angle during seoi-nage skill compared with novice judo athletes. In addition, the shoulder and pelvis of expert judo athletes exhibited together while maintaining the extension of the hip and knee joints to achieve effective sedation than novice judo athletes.
Conclusions
These results suggest that the force and movement control is important for the implementation of optimal the seoi-nage skill.
Percutaneous endoscopic transforaminal discectomy for thoracolumbar disc herniation: A retrospective study
Authors: chen hao , bian zhenyu , hou changju , li maoqiang , zhang zhen , zhu liulong , wang xuepeng 
Published: January 2023

Abstract
Purpose: Thoracolumbar disc herniation, a rare disorder, has unique characteristics that can result in undesirable surgical outcomes after traditional discectomy. In view of the widespread use of percutaneous endoscopic transforaminal discectomy for lower lumbar disc herniation, we investigated treatment of thoracolumbar disc herniation by this procedure. The purpose of this study was to evaluate the clinical efficacy and surgical outcomes of percutaneous endoscopic transforaminal discectomy for treating thoracolumbar disc herniation.
Methods: We retrospectively evaluated the clinical data of 19 patients who had undergone percutaneous endoscopic transforaminal discectomy for thoracolumbar disc herniation in our institution between April 2018 and July 2021. Operation time, follow-up time, blood loss, postoperative hospital stay, visual analogue scale scores for low-leg and leg pain, and Japanese Orthopedic Association scores were evaluated.
Results: The differences between preoperative and postoperative Japanese Orthopedic Association and visual analogue scale scores were significant (P<0.05). According to the Japanese Orthopedic Association scores, 14 of the 19 patients had excellent, three good, and two fair improvement; thus, the rate of satisfactory improvement was 89.5%.
Conclusion: Operation time, blood loss, postoperative hospital stay, and surgical outcomes were favorable. Percutaneous endoscopic transforaminal discectomy is an ideal surgical procedure for treating thoracolumbar disc herniation.
Cross-sectional area of peripheral nerve in amyotrophic lateral sclerosis: a case-control study
Authors: Fan Jing , Li Yi , Niu Jingwen , Guan Yuzhou , Cui Liying , Liu Mingsheng 
Published: January 2023

Abstract
Background: This study aims to determine CSA of peripheral nerve and whether CSA could act as a predictor of disease prognosis in patients with ALS.
Methods: a total of 139 patients and 75 healthy controls were recruited, 39 patients were lost to follow-up. The ALS functional rating scale Revised (ALS-FRS-R), duration from onset to diagnosis, and survival duration were collected. Peripheral nerve CSAs were measured at the first visit on the bilateral median, and ulnar nerve in ALS patients and controls.
Results: Compared to controls, ALS patients had mild reductions of the median nerve and most sites of the ulnar nerve. Another important finding of this study is that the median nerve tends to have a more significant reduction than the ulnar nerve in ALS patients, especially at the proximal. However, no significant correlation was observed between CSAs and ALS-FRS-R/m. The K-M curve indicated no correlation between CSAs and survival in patients with upper limber onset ALS.
Conclusions: CSA at the proximal Median nerve may be a promising biomarker in patients with ALS. While Peripheral nerve CSAs of the upper limb were not correlated with survival and severity of disease in patients with ALS.
Trial registration: This study was approved by the Ethics Committee of the Peking Union Medical College Hospital, approval number (JS-1210).
Relationship between key continuous glucose monitoring-derived metrics and specific cognitive domains in patients with type 2 diabetes mellitus
Authors: Dong Shanshan , Wang Lina , Zhao Chenxu , Zhang Rui , Gao Zhaoyu , Jiang Lei , Guo Yingying , Zhou Huimin , Xu Shunjiang 
Published: January 2023

Abstract
Objective
Continuous glucose monitoring (CGM)-derived time in range (TIR) is closely associated with micro- and macro-vascular complications in type 2 diabetes mellitus (T2DM). This study was performed to investigate the relationship between key CGM metrics and specific cognitive domains in patients with T2DM.
Methods
A total of 96 outpatients with T2DM were recruited in this study. A battery of neuropsychological tests was performed to evaluate cognitive function, including memory, executive functioning, visuospatial ability, attention, and language. Participants wore a blinded flash glucose monitor (FGM) for 72 h. The key FGM metrics were calculated, including TIR, time below range (TBR), and time above range (TAR). Furthermore, the glycemia risk index (GRI) was also calculated by the GRI formula. Binary logistic regression was used to assess risk factors for TBR, and we further analyzed the associations between neuropsychological test results and TBR/TAR/TIR/GRI with multiple linear regressions.
Results
A total of 45.8% of patients with T2DM had hypoglycemia (TBR < 3.9) measured by FGM. The Spearman analysis results revealed that a higher TBR < 3.9 was correlated with worse performance on trail making test A (TMTA), clock drawing test (CDT) and cued recall scores (P < 0.05). The logistic regression analysis results revealed that TMTA (OR = 1.010, P = 0.036) and CDT (OR = 0.429, P = 0.016) scores were independent factors influencing the occurrence of TBR < 3.9. Multiple linear regressions revealed that TBR < 3.9 (β = -0.214, P = 0.033), TAR > 13.9 (β = -0.216, P = 0.030) and TAR 10.1–13.9 (β = 0.206, P = 0.042) were significantly correlated with cued recall scores after adjusting for confounding factors. TIR and GRI had no correlation with neuropsychological test results (P > 0.05).
Conclusion
A higher TBR < 3.9 and TAR > 13.9 were associated with worse cognitive functions (memory, visuospatial ability, and executive functioning). A higher TAR of 10.1–13.9 was associated with better memory performance. For patients with T2DM, glycemic targets can be relaxed to 10.1–13.9 mmol/L, which may slow the decline in cognitive function.
Factors associated with the CVD risk factors and body fat pattern of postmenopausal Hindu caste and Lodha tribal populations living in India: An exploratory study
Authors: Roy Subho , Kar Debasmita 
Published: January 2023

Abstract

Background Loss in ovarian function during mid-life results in adverse changes in cardiovascular profile of women. The strength of the association between CVD risk factors and menopause differ cross culturally since several modifiable factors play significant roles in explaining CVD mortality than differences in endogenous estrogen. Very few of the studies from this subcontinent have been concerned with the menopause specific CVD risk factors, particularly among the tribal groups. Thus, we intended to study the variations in body fat pattern and CVD risk factors between Hindu caste and Lodha tribal postmenopausal women and how these risk factors can be predicted from differential socio-economic, reproductive and menstrual characteristics and lifestyle variables. The Lodha tribal populations is considered as Particularly Vulnerable Group (PVTG) in this country. Methods This cross-sectional study was conducted among the Bengali Hindu caste and Lodha tribal populations of the State of West Bengal, India covering three districts namely Howrah, Jhargram and East Midnapure. A total number of 197 postmenopausal participants have been recruited for this study (urban caste 69, rural caste 65 and rural Lodha 63). Data on blood sugar and total cholesterol levels, blood pressure, muscle mass, body fat distribution and sociodemographic, reproductive and menstrual history and lifestyle variables were collected following standard protocols. The entire data was analyzed with the help of statistical package for social science version 20.0(IBM corporation, 2011). Results This cross-sectional comparison of women at midlife, though exploratory in nature showed significant differences in body fat pattern and CVD risk factors between caste and tribal groups owing to the socioeconomic disparities, differences in reproductive characteristic and lifestyle factors. Conclusion The caste and tribal populations differed significantly in body fat pattern and CVD risk factors and the concomitants to these problems, suggesting interplay between menopause and modifiable factors in explaining CVD risk factors during mid-life.
Missed diagnoses of Blunt Cerebrovascular Injuries result in Ischemic stroke: two cases report
Authors: Zhang Shaoyang , Wu Mingjie , Fu Qinghui , Zhou Qian , Jiang Meng , Wang Yadong , Wang Weier , Yang Xiaofeng 
Published: January 2023

Abstract
Here we report two patients with a car accident injury who suffered a cerebral infarction following a missed diagnosis of blunt cerebrovascular injury. Difficulty in diagnosis of these cases because of no neurological signs or symptoms on initial assessment is a lesson for physicians from emergency room. Our conclusion upon dealing with the situation is that traumatic blunt cerebrovascular injury has potentially devastating consequences. There is often a delay between the trauma and the onset of symptoms of neurological deficit. Therefore, clinicians should be cautious in this situation. Early detection and intervention are needed to prevent the development of ischemic stroke secondary to blunt cerebrovascular injury in combination with cerebral infarction, thereby improving the prognosis of patients.
PTEN regulates actin filaments to shape cell cortex architecture
Authors: Ho Kimberly , Patel Suraj S. , Sullivan Eve , Chang Alicia , Lin Guang Han , Lv Moqi , Fan Xinyi , Naufal E. R. , Shen Wen H. 
Published: January 2023

Abstract
Mitosis and homeostasis depend on proper cellular morphological transformation and plasma membrane structure during interphase. PTEN is a tumor suppressor protein involved in cellular homeostasis and genomic stability. We have previously shown that loss of PTEN leads to impairment of mitotic spindle architecture and cytokinesis. Here we report a potential relationship between PTEN and actin in controlling cellular morphology. PTEN depletion results in disorganization of the actin cytoskeleton. This is manifested by decreased parallel alignment of actin filaments, increased F-actin at the membrane, and cells appeared rounder. We also found that Moesin (Moe), an actin-binding ERM protein involved in membrane morphology, exhibits greater level in the phosphorylated Moe (pMoe) form and dislocation of pMoe from the cell cortex. Using an inhibitor of actin polymerization in PTEN-deficient cells, our data show a reduced quantity of pMoe and the recovery of its membrane enrichment. Moreover, inhibition of actin polymerization also reduces F-actin at the membrane and the frequency of cells with round shape. These data suggest that PTEN may regulate cortical actin polymerization to maintain cellular morphology and membrane dynamics.
Survey the effectiveness of education based on Message Framing through mobile phone on women's physical activity
Authors: Shakerinejad Ghodratollah , Baji Zahra , Tehrani Masoumeh , Jarvandi Farzaneh , Cheraghi Maria , Hatamzadeh Nasser 
Published: January 2023

Abstract
Background: Physical activity in female employees is a healthy behavior and increases strength, endurance, improves flexibility, improves the feeling of vitality and freshness, improves health, and ultimately increases life expectancy. Health messages are one of the most effective ways to engage people and motivate them to perform healthy behaviors. The purpose of this study was to the study of the effectiveness of education based on message framing through mobile phone (whatsapp) on the physical activity of women employees of universities and higher education institutions in Ahvaz city.
Method: In this interventional study, 90 of female employees of universities and higher education institutions of Ahvaz city were selected by random sampling and randomly divided into three groups (30 participants) receiving gain framed messages, receiving loss framed messages and the control group. The tools of data collection were demographic information questionnaire and international physical activity questionnaire (IPAQ). The participants of the intervention groups received educational messages about physical activity behavior in two different gain and loss framed messages through whatsapp for one month. Data were collected from three groups at the beginning of the study, immediately and two months after the intervention, and were analyzed using SPSS version 26.
results: The results showed that there was a significant increase in the average physical activity score after the intervention. It was also found that this increase in the group of gain framed messages for physical activity behavior was significantly higher than the group of loss framed messages.
Conclusion: The results of this study showed that the design and implementation of education programs based on message framing, especially gain framed messages through online education (Whatsapp) can improve and promote physical activity behavior in women employees.
Validity and utility of a vascular resistance-integrated diastolic index as a prognostic factor in heart failure with preserved ejection fraction
Authors: Hoshida Shiro 
Published: January 2023

Abstract
None of the existing non-invasive diastolic indices consider arterial load. This article proposed the validity of a novel index of vascular resistance-integrated diastolic function, a ratio of left ventricular diastolic elastance (Ed) to arterial elastance (Ea), Ed/Ea = (E/e´)/(0.9 × systolic blood pressure), and its utility in the prognostic evaluation of patients with heart failure with preserved ejection fraction (HFpEF). Prognostic factors related to left atrial overload such as Ed/Ea may differ according to the clinical endpoint, follow-up duration and sex. In HFpEF patients with heterogenous cardiac structure and function, assessment using a serial echocardiographic vascular resistance-integrated diastolic index in clinical care can provide an accurate prognosis.
Effect of Different Pretreated Acids on Gel Strength of Gelatin
Authors: mairaj Asma , Saeed Muhammad Faran 
Published: January 2023

Abstract
The usage of gelatin is limited due to its instability and poor mechanical properties. Under special physiological conditions. So when we treated the hides in which buffalo and cowhide were pretreated with different acids so they disrupt the cross-links and release acid-soluble proteins and others components. Generally, to achieve optimum extraction efficiency, strong acid may be used at a lower concentration compared to weak acid. This study aimed to determine the gel strength of gelation extracted from different kinds of hides (buffalo or cow hides) pretreated with different kinds of acids. Mostly hides were extracted with Hydrochloric acid, citric acid, and acetic acid. So we use different concentrations of 0.3, 0.6, 0.9, 1.2, and 1.5M of acids, to check the impact on gel strength.in general the gel strength property of the gelatin compiled with the industry standard set by the gelatin manufacture institute of America revealing that buffalo hide could serve as a suitable alternative source of gelatin.
Epidemiology of Major Paediatric Trauma in a European Country – Trends of a Decade
Authors: Castelão Mafalda , Lopes Graça , Vieira Marisa 
Published: January 2023

Abstract
Objectives
This study describes the epidemiology of severe injuries related to trauma in children and assesses potential preventive areas.
Methods
Single-centre retrospective study of paediatric trauma patients admitted to a Paediatric Intensive Care Unit (PICU) in a tertiary university hospital in Europe, from 2009 to 2019.
Results
Total 358 patients included (age 11 ± 4,9 years; 67% male); 75% were involved in road traffic accidents: 30% motor vehicle collision, 25% pedestrian, 10% motorcycle and bicycle each. Falls from height injured 19% of children, 4% during sports activities. Main injuries were to head/neck (73%) and extremities (42%). The incidence of major trauma was highest in teenagers and did not show a decreasing trend during the study years. All fatalities (1,7%; n = 6) were related to head/neck injuries. Motor vehicle collisions resulted in higher need for blood transfusion (9 vs 2 mL/kg, p = 0,006) and the highest ICU-mortality (83%; n = 5). Children in motorcycle accidents had longer ICU length-of-stay (6,4 vs 4,2 days, p = 0,036). Pedestrians had 25% higher risk of head/neck injuries (RR 1,25; 1,07 − 1,46; p = 0,004), and higher incidence of severe brain injury (46% vs 34%, p = 0,042). Most children in motor-vehicle/bicycle accidents were not using restraints/protective devices (45%) or were using them inappropriately (13%).
Conclusions
Over the last decade, the absolute numbers of paediatric major trauma did not decrease. Road traffic accidents remain the leading cause of injury and death. Teenagers are at highest risk for severe trauma. Appropriate use of child restraints and protective equipment remain key for prevention.
Multiparametric MRI for the differentiation of brain glial cell hyperplasia from low-grade glioma
Authors: Gu Si Qian , Qian Jing , Yang Ling , Sun Zhi Lei , Hu Chun Hong , Wang Xi Ming , Hu Su 
Published: January 2023

Abstract
Background
For individualized clinical treatment of patients,The differentiation between brain glial cell hyperplasia and low-grade glioma is of significant importance.
Objective
Based on Multiparametric MRI images,combining with clinical risk factors,we construct a radiomics-clinical model and nomogram for the differentiation of brain glial cell hyperplasia from low-grade glioma.
Methods
We retrospectively included patients with brain glial cell hyperplasia and low-grade glioma who underwent surgery at the First Affiliated Hospital of Soochow University from March 2016 to March 2022.A total of 41 patients of brain glial cell hyperplasia and 87 patients of low-grade glioma were included in this study,then divide them into training group and validation group randomly with a ratio of 7: 3.We extracted radiomics features from T1-weighted imaging(T1WI),T2-weighted imaging(T2WI), diffusion-weighted imaging(DWI), contrast-enhanced T1-weighted imaging (T1-enhanced),then built LASSO, SVM and RF model,and we selected a model with higher efficiency to calculate the Rad-score (radiomics score) of every patient. To obtain the independent risk factors,we screened the Rad-score and clinical risk factors by univariate and multivariate logistic regression analysis in turn, then we constructed radiomics-clinical model, and evaluated their performance.
Results
Of the included 128 cases ,brain glial cell hyperplasia and low-grade gliomas were randomly divided into 10 groups, and 7 of them were used as training group and 3 as validation group. The radiomics-clinical model were constructed with two independent risk factors——mass effect and Rad-score,which AUCs of the training group and validation group were 0.847 and 0.858. The diagnostic accuracy, sensitivity, and specificity of the validation group were 0.821,0.750,0.852.
Conclusion
Combining with radiomics constructed by multiparametric MRI images and clinical features,the radiomics-clinical model and nomogram which were constructed to differentiate between brain glial cell hyperplasia and low-grade glioma had a good performance.
RGS4 impacts carbohydrate and siderophore metabolism in Trichoderma reesei
Authors: Schalamun Miriam , Molin Eva-Maria , Schmoll Monika 
Published: January 2023

Abstract
Adaptation to complex, rapidly changing environments is crucial for evolutionary success of fungi. The heterotrimeric G-protein pathway belongs to the most important signaling cascades applied for this task. In Trichoderma reesei, enzyme production, growth and secondary metabolism are among the physiological traits influenced by the G-protein pathway in a light dependent manner. Here, we investigated the function of the SNX/H-type regulator of G-protein signaling (RGS) protein RGS4. We show that RGS4 is involved in regulation of cellulase production, growth, asexual development and stress response. Transcriptome analysis revealed regulation of six genes mutated in RutC30 as well as several genes encoding transcription factors and transporters. Importantly, RGS4 positively regulates the siderophore cluster responsible for fusarinine C biosynthesis in light and the respective deletion mutant shows altered growth on nutrient sources related to siderophore production. Additionally, growth on storage carbohydrates as well as several intermediates of the D-galactose and D-arabinose catabolic pathway is decreased, predominantly in light. We conclude that RGS4 mainly operates in light and targets plant cell wall degradation, siderophore production and storage compound metabolism in T. reesei.
Prenatal depression and its predictors among women who seek prenatal care at mettu karl specialized hospital, south west Ethiopia
Authors: Dibaba Bekem 
Published: January 2023

Abstract
Introduction

: Globally, Prenatal depression is the most prevalent psychological problem which women experience during pregnancy. Regardless of the impact on maternal health; Risk factors of antenatal depression is poorly studied in Ethiopia. Therefore the goal of this study was to determine the risk factors of antenatal depression among pregnant women attending antenatal care.

Objective

The goal of the study was to determine how common prenatal depression and factors influencing it among women receiving antenatal care at Mettu Karl Specialized Hospital in southwest Ethiopia.

Methods and Materials

A cross-sectional study was undertaken from September 15 to October 15/2021. A total of 343 women were chosen using a systematic random sample technique. SPSS version 23.0 was used to analyze the data. In the bi-variable logistic regression, variables having a P-value of less than 0.25 at a 95% confidence interval were added to the multivariable logistic regression. Finally, in multivariable logistic regression, factors with a P-value of 0.05 at a 95% confidence Interval were declared significantly associated with prenatal depression.

Result

A total of 343 pregnant mothers were participated, making a 95% response rate. The magnitude of prenatal depression was 27.6%. The result of multivariable logistic regression analysis showed that respondents who had unplanned pregnancies were 2.1 times more likely to develop prenatal depression comparing with their counterparts. Pregnant mothers who had complications during their previous labor and delivery were 4.4 times more likely to develop prenatal depression compared with those who had no complications during previous labor and delivery. Furthermore, participants with a past history of child hospitalization were 3.3 times more likely to develop prenatal depression compared with those who have no past history of child hospitalization. At long last, respondents who had satisfaction with their marriage were 3.9 times less likely to develop prenatal depression compared with those who had no satisfaction with their marriage

Conclusion

Generally, the magnitude of antenatal depression is still high. To prevent further consequences, interventions like working on the identified risk factors are mandatory.