bluuebunny/crossref_metadata_2025_split huggingface dataset:
Post-processing of real-time quantum event measurements for an optimal bandwidth
Authors: Kerski J. , Mannel H. , Lochner P. , Kleinherbers E. , Kurzmann A. , Ludwig A. , Wieck A. D. , König J. , Lorke A. , Geller M. 
Published: January 2023

AbstractSingle electron tunneling and its transport statistics have been studied for some time using high precision charge detectors. However, this type of detection requires advanced lithography, optimized material systems and low temperatures (mK). A promising alternative, recently demonstrated, is to exploit an optical transition that is turned on or off when a tunnel event occurs. High bandwidths should be achievable with this approach, although this has not been adequately investigated so far. We have studied low temperature resonance fluorescence from a self-assembled quantum dot embedded in a diode structure. We detect single photons from the dot in real time and evaluate the recorded data only after the experiment, using post-processing to obtain the random telegraph signal of the electron transport. This is a significant difference from commonly used charge detectors and allows us to determine the optimal time resolution for analyzing our data. We show how this post-processing affects both the determination of tunneling rates using waiting-time distributions and statistical analysis using full-counting statistics. We also demonstrate, as an example, that we can analyze our data with bandwidths as high as 175 kHz. Using a simple model, we discuss the limiting factors for achieving the optimal bandwidth and propose how a time resolution of more than 1 MHz could be achieved.
Research on sand body architecture at the intersection of a bidirectional sedimentary system in the Jiyuan area of Ordos Basin
Authors: Tong Qiang , He Dongbo , Xia Zhaohui , Huang Jixin , Li Yunbo , Xu Fang , Guo Songwei 
Published: January 2023

AbstractThe exploration and development of the dual-provenance lower assemblage of the Yanchang Formation in the Jiyuan area has progressed rapidly. At the intersection of this bidirectional provenance system, a complex and variable spatial combination of sand bodies formed, resulting in significant structural heterogeneity in the development and distribution of reservoirs. Based on previous studies, this paper combines core data and logging data with a large number of analytical tests and production performance data to carry out research on the Chang 82–Chang 9 reservoir group in the lower assemblage of the Yanchang Formation in the Shijiawan-Buziwan area. Based on the analysis of sedimentary conditions, the sand body development pattern at the intersection of the bidirectional sedimentary system in the study area was analysed by stepwise dissection of the sand body architecture. After the types and characteristics of the 4th- to 5th-level architectural elements were determined, the spatial distribution of the combinations of these elements was assessed and combined with logging discriminant analysis and geometric shape prediction methods to identify a ‘prism’ architectural distribution pattern. The architectural elements are connected with the distribution of diagenetic facies, the spatial distribution patterns of different types of diagenetic facies under the constraints of the architecture are summarized by region, and the locations of potential favourable reservoir development are discussed. The results show that the degree of superposition and combination of the eight skeletal architectural elements in the target layers gradually deteriorate from the bottom to the top. In addition, the development scale and degree of architectural elements in the braided river delta system in the west are better than those in the meandering river delta system in the east. In the different sedimentary areas, the spatial combination styles of the architectural elements are quite different, and the combination of these elements gradually changes from a combination of braided channels (FA1) and abandoned channels (FA2) to a combination of underwater distributary channels (FA4). Matching of the distribution of diagenetic facies with the distribution of architectural elements reveals that the diagenetic facies dominated by intergranular pores and dissolution pores (associated with good reservoir physical properties) are usually found at the bottom or in the lower to middle parts of the skeletal architectural elements.
Particle simulation of the strong magnetic field effect on dust particle charging process
Authors: Davari Hadi , Farokhi Bizhan , Ali Asgarian Mohammad 
Published: January 2023

AbstractA particle-in-cell simulation is modeled and run on a dusty plasma to determine the effect of the magnetic field on the process of dust-particle charging through electron–ion plasma. The electric field is solved through the Poisson equation, and the electron-neutral elastic scattering, excitation, and ionization processes are modeled through Monte Carlo collision method. The effects observed from the initial density of the plasma, the initial temperature of the electrons, and the changing magnetic field are included in this simulation model. In the dust particle charging process, saturation time and saturation charge are compared. An increase in the magnetic field does not reduce time to reach the saturation state. Determining the magnetic field boundaries which depend on the physical properties of the plasma, can be contributive in some areas of dusty(complex) plasma. The applications of the results obtained here for fusion plasma conditions and space and laboratory plasmas are discussed. The results here can be applied in future simulation models with a focus on the dust particle movement and their effect on plasma, leading to the modeling of different astrophysical plasmas thorough laboratory experiments.
A novel microfluidic device with parallel channels for sperm separation using spermatozoa intrinsic behaviors
Authors: Heydari Ali , Zabetian Targhi Mohammad , Halvaei Iman , Nosrati Reza 
Published: January 2023

AbstractIsolating high-quality motile sperm cells is considered to be the main prerequisite for a successful artificial pregnancy. Microfluidics has emerged as a promising platform capable of mimicking in-vivo environments to separate motile sperm cells and bypassing the need for the current invasive clinical sperm separation methods. In this study, the proposed microfluidic device exploits the parallelization concept through symmetry to increase both the processed sample volume and the injected flow rate compared with the previous conventional devices, which used rheotaxis as their primary method of sperm separation. Using the finite element method (FEM) and flow simulations, the trajectories of sperm cells exhibiting rheotaxis behavior were predicted inside the proposed device. Different flow rates, including 0, 0.5, 1.5, 3, 4.5 and 6 μl/min, were experimentally injected into the device, and the effect of flow rate on the size of the hypothetical rheotaxis zone and the number of isolated sperm cells was investigated. Furthermore, it was illustrated that 100% of the isolated motile sperm cells are motile, and by manipulating the injected flow rate into the device, different classes of sperm cells in terms of motility parameters can be separated and utilized for further uses.
Identification of platelet subpopulations in cryopreserved platelet components using multi-colour imaging flow cytometry
Authors: Johnson Lacey , Lei Pearl , Waters Lauren , Padula Matthew P. , Marks Denese C. 
Published: January 2023

AbstractCryopreservation of platelets, at  − 80 °C with 5–6% DMSO, results in externalisation of phosphatidylserine and the formation of extracellular vesicles (EVs), which may mediate their procoagulant function. The phenotypic features of procoagulant platelets overlap with other platelet subpopulations. The aim of this study was to define the phenotype of in vitro generated platelet subpopulations, and subsequently identify the subpopulations present in cryopreserved components. Fresh platelet components (n = 6 in each group) were either unstimulated as a source of resting platelets; or stimulated with thrombin and collagen to generate a mixture of aggregatory and procoagulant platelets; calcium ionophore (A23187) to generate procoagulant platelets; or ABT-737 to generate apoptotic platelets. Platelet components (n = 6) were cryopreserved with DMSO, thawed and resuspended in a unit of thawed plasma. Multi-colour panels of fluorescent antibodies and dyes were used to identify the features of subpopulations by imaging flow cytometry. A combination of annexin-V (AnnV), CD42b, and either PAC1 or CD62P was able to distinguish the four subpopulations. Cryopreserved platelets contained procoagulant platelets (AnnV+/PAC1−/CD42b+/CD62P+) and a novel population (AnnV+/PAC1−/CD42b+/CD62P−) that did not align with the phenotype of aggregatory (AnnV−/PAC1+/CD42b+/CD62P+) or apoptotic (AnnV+/PAC1−/CD42b−/CD62P−) subpopulations. These data suggests that the enhanced haemostatic potential of cryopreserved platelets may be due to the cryo-induced development of procoagulant platelets, and that additional subpopulations may exist.
Ignition of the southern Atlantic seafloor spreading machine without hot-mantle booster
Authors: Sauter Daniel , Manatschal Gianreto , Kusznir Nick , Masquelet Charles , Werner Philippe , Ulrich Marc , Bellingham Paul , Franke Dieter , Autin Julia 
Published: January 2023

AbstractThe source of massive magma production at volcanic rifted margins remains strongly disputed since the first observations of thick lava piles in the 1980s. However, volumes of extruded and intruded melt products within rifted continental crust are still not accurately resolved using geophysical methods. Here we investigate the magma budget alongside the South Atlantic margins, at the onset of seafloor spreading, using high-quality seismic reflection profiles to accurately estimate the oceanic crustal thickness. We show that, along ~ 75% of the length of the Early-Cretaceous initial spreading centre, the crustal thickness is similar to regular oceanic thickness with an age > 100 Ma away from hot spots. Thus, most of the southernmost Atlantic Ocean opened without anomalously hot mantle, high magma supply being restricted to the Walvis Ridge area. We suggest that alternative explanations other than a hotter mantle should be favoured to explain the thick magmatic layer of seaward dipping reflectors landward of the initial mid-oceanic ridge.
Cooperation without punishment
Authors: Battu Balaraju , Rahwan Talal 
Published: January 2023

AbstractA fundamental question in social and biological sciences is whether self-governance is possible when individual and collective interests are in conflict. Free riding poses a major challenge to self-governance, and a prominent solution to this challenge has been altruistic punishment. However, this solution is ineffective when counter-punishments are possible and when social interactions are noisy. We set out to address these shortcomings, motivated by the fact that most people behave like conditional cooperators—individuals willing to cooperate if a critical number of others do so. In our evolutionary model, the population contains heterogeneous conditional cooperators whose decisions depend on past cooperation levels. The population plays a repeated public goods game in a moderately noisy environment where individuals can occasionally commit mistakes in their cooperative decisions and in their imitation of the role models’ strategies. We show that, under moderate levels of noise, injecting a few altruists into the population triggers positive reciprocity among conditional cooperators, thereby providing a novel mechanism to establish stable cooperation. More broadly, our findings indicate that self-governance is possible while avoiding the detrimental effects of punishment, and suggest that society should focus on creating a critical amount of trust to harness the conditional nature of its members.
High-dimensional quantum key distribution implemented with biphotons
Authors: Sekga Comfort , Mafu Mhlambululi , Senekane Makhamisa 
Published: January 2023

AbstractWe present a high-dimensional measurement device-independent (MDI) quantum key distribution (QKD) protocol employing biphotons to encode information. We exploit the biphotons as qutrits to improve the tolerance to error rate. Qutrits have a larger quantum system; hence they carry more bits of classical information and have improved robustness against eavesdropping compared to qubits. Notably, our proposed protocol is independent of measurement devices, thus eliminating the possibility of side-channel attacks. Also, we employ the finite key analysis approach to study the performance of our proposed protocol under realistic conditions where finite resources are used. Furthermore, we simulated the secret key rate for the proposed protocol in terms of the transmission distance for different fixed amounts of signals. The results prove that this protocol achieves a considerable secret key rate for a moderate transmission distance of 90 km by using $$10^{16}$$

10
16

signals. Moreover, the expected secret key rate was simulated to examine our protocol’s performance at various intrinsic error rate values, $$Q=(0.3\%,0.6\%,1\%)$$

Q
=
(
0.3
%
,
0.6
%
,
1
%
)

caused by misalignment and instability due to the optical system. These results show that reasonable key rates are achieved with a minimum data size of about $$10^{14}$$

10
14

signals which are realizable with the current technology. Thus, implementing MDI-QKD using finite resources while allowing intrinsic errors due to the optical system makes a giant step forward toward realizing practical QKD implementations.
Simultaneous electro-generation/polymerization of Cu nanocluster embedded conductive poly(2,2′:5′,2′′-terthiophene) films at micro and macro liquid/liquid interfaces
Authors: Moshrefi Reza , Przybyła Hanna , Stockmann Talia Jane 
Published: January 2023

AbstractCu nanoparticles (NPs) have been shown to be excellent electrocatalysts, particularly for CO2 reduction – a critical reaction for sequestering anthropogenic, atmospheric carbon. Herein, the micro interface between two immiscible electrolyte solutions (ITIES) is exploited for the simultaneous electropolymerization of 2,2′:5′,2′′-terthiophene (TT) and reduction of Cu2+ to Cu nanoparticles (NPs) generating a flexible electrocatalytic composite electrode material. TT acts as an electron donor in 1,2-dichloroethane (DCE) through heterogeneous electron transfer across the water|DCE (w|DCE) interface to CuSO4 dissolved in water. The nanocomposite formation process was probed using cyclic voltammetry as well as electrochemical impedance spectroscopy (EIS). CV and EIS data show that the film forms quickly; however, the interfacial reaction is not spontaneous and does not proceed without an applied potential. At high [TT] the heterogeneous electron transfer wave was recorded voltammetrically but not at low [TT]. However, probing the edge of the polarizable potential window was found to be sufficient to initiate electrogeneration/electropolymerization. SEM and TEM were used to image and analyze the final Cu NP/poly-TT composites and it was discovered that there is a concomitant decrease in NP size with increasing [TT]. Preliminary electrocatalysis results at a nanocomposite modified large glassy carbon electrode saw a > 2 × increase in CO2 reduction currents versus an unmodified electrode. These data suggest that this strategy is a promising means of generating electrocatalytic materials for carbon capture. However, films electrosynthesized at a micro and ~ 1 mm ITIES demonstrated poor reusability.
Handgrip strength is inversely associated with augmentation index in patients with type 2 diabetes
Authors: Hamasaki Hidetaka , Yanai Hidekatsu 
Published: January 2023

AbstractHandgrip strength (HGS) is a measure of overall skeletal muscle strength and is used to identify risks for cardiovascular disease and mortality. Furthermore, HGS is an indicator of arterial stiffness that leads to atherosclerotic cardiovascular disease. This study aimed to examine the relationship between HGS and augmentation index (AIx) in patients with type 2 diabetes. A cross-sectional study was conducted to examine patients with type 2 diabetes whose HGS and AIx were measured in our hospital. AIx was measured noninvasively using an applanation tonometer, and multiple regression analyses were conducted to assess the independent relationship between HGS and AIx. This study included 404 patients. After adjusting for age, gender, body mass index, duration of diabetes, smoking and exercise habit, biochemical parameters, and physiological parameters related to arterial stiffness, HGS was found to be independently and inversely associated with AIx (β = − 0.270, p = 0.006). HGS was independently and inversely associated with AIx in patients with type 2 diabetes. Patients with diminished HGS should be subjected to intensive exercise therapy for reducing the risk of arterial stiffness and cardiovascular disease.Trial registration: UMIN000023010.
Psychosocial work conditions and prediabetes risks: a cross-sectional study in middle-aged men and women
Authors: Schmidt C. , Gummesson A. , Bäckhed F. , Bergström Göran , Söderberg M. 
Published: January 2023

AbstractPrediabetes is a condition between diabetes and normoglycemia, and is a state of major health concern, as a large proportion of people with prediabetes are likely to develop diabetes which is associated with high mortality and morbidity. The purpose of this study was to investigate whether adverse psychosocial work conditions, based on the Job Demand-Control-social support model, increases risk for early dysregulated glucose metabolism in 50–64-year-old men and women. Job conditions were measured with the Swedish Demand-Control-Support questionnaire. Impaired glucose metabolism was assessed by an oral glucose tolerance test. Differences between groups were analyzed with Chi-square test and one-way ANOVA with Bonferroni post-hoc test. Odds ratios (OR) and 95% confidence intervals (95% CI) between Job Demand-control-support and prediabetes outcome were calculated with multiple logistic regression. Results from an adjusted logistic regression model showed that in men and woman separately, an active work situation (high demands-high control) was associated with significantly lower prediabetes risk (OR 0.657, 95% CI 0.513–0.842). This finding is consistent through all logistic regression models with different levels of adjustments. Further, the current study does not lend support for the hypothesis that work conditions characterized by high demands-low control were associated with dysregulated glucose metabolism in men nor women despite accumulation of many life-style related risk factors in the high strain group. In conclusion, we could show that men and women assessing their work conditions as active, had lower risk for prediabetes.
Evaluation of critical care burden following traumatic injury from two randomized controlled trials
Authors: Campwala Insiyah , Guyette Francis X. , Brown Joshua B. , Yazer Mark H. , Daley Brian J. , Miller Richard S. , Harbrecht Brian G. , Claridge Jeffrey A. , Phelan Herbert A. , Eastridge Brian , Nirula Raminder , Vercruysse Gary A. , O’Keeffe Terence , Joseph Bellal , Neal Matthew D. , Zuckerbraun Brian S. , Sperry Jason L. 
Published: January 2023

AbstractTrauma resuscitation practices have continued to improve with new advances targeting prehospital interventions. The critical care burden associated with severely injured patients at risk of hemorrhage has been poorly characterized. We aim to describe the individual and additive effects of multiorgan failure (MOF) and nosocomial infection (NI) on delayed mortality and resource utilization. A secondary analysis of harmonized data from two large prehospital randomized controlled trials (Prehospital Air Medical Plasma (PAMPer) Trial and Study of Tranexamic Acid during Air and Ground Medical Prehospital Transport (STAAMP) Trial) was conducted. Only those patients who survived beyond the first 24 hours post-injury and spent at least one day in the ICU were included. Patients were stratified by development of MOF only, NI only, both, or neither and diagnosis of early (≤ 3 days) versus late MOF (> 3 days). Risk factors of NI and MOF, time course of these ICU complications, associated mortality, and hospital resource utilization were evaluated. Of the 869 patients who were enrolled in PAMPer and STAAMP and who met study criteria, 27.4% developed MOF only (n = 238), 10.9% developed NI only (n = 95), and 15.3% were diagnosed with both MOF and NI (n = 133). Patients developing NI and/or MOF compared to those who had an uncomplicated ICU course had greater injury severity, lower GCS, and greater shock indexes. Early MOF occurred in isolation, while late MOF more often followed NI. MOF was associated with 65% higher independent risk of 30-day mortality when adjusting for cofounders (OR 1.65; 95% CI 1.04–2.6; p = 0.03), however NI did not significantly affect odds of mortality. NI was individually associated with longer mechanical ventilation, ICU stay, hospital stay, and rehabilitation requirements, and the addition of MOF further increased the burden of inpatient and post-discharge care. MOF and NI remain common complications for those who survive traumatic injury. MOF is a robust independent predictor of mortality following injury in this cohort, and NI is associated with higher resource utilization. Timing of these ICU complications may reveal differences in pathophysiology and offer targets for continued advancements in treatment.
Genome-wide analysis of the CML gene family and its response to melatonin in common bean (Phaseolus vulgaris L.)
Authors: Zhao Hongyan , Gao Yamei , Du Yanli , Du Jidao , Han Yiqiang 
Published: January 2023

AbstractCalmodulin-like proteins (CML) are important calcium signal transduction proteins in plants. CML genes have been analyzed in several plants. However, little information on CML in Phaseolus vulgare is available. In this study, we identified 111 PvCMLs distributed on eleven chromosomes. Phylogenetic analysis classified them into seven subfamilies. Cis-acting element prediction showed that PvCML contained elements related to growth and development, response to abiotic stress and hormones. Moreover, the majority of PvCMLs showed different expression patterns in most of the nine tissues and developmental stages which indicated the role of PvCML in the growth and development of common bean. Additionally, the common bean was treated with melatonin by seed soaking, and root transcriptome at the 5th day and qRT-PCR of different tissue at several stages were performed to reveal the response of PvCML to the hormone. Interestingly, 9 PvCML genes of subfamily VI were detected responsive to exogenous melatonin, and the expression dynamics of nine melatonin response PvCML genes after seed soaking with melatonin were revealed. Finally, the protein interaction network analysis of nine melatonin responsive PvCMLs was constructed. The systematic analysis of the PvCML gene family provides theoretical support for the further elucidation of their functions, and melatonin response molecular mechanism of the CML family in P. vulgaris.