bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pleomorphic Adenoma-a Case Report
Authors: Subashini V  
Published: February 2023

Among neoplasia of head and neck, Salivary gland tumours are rare and it comprises about less than 3%.Pleomorphic adenoma is the most common benign tumour of all salivary gland tumours, which is so called mixed tumour due its wide cyto-morphological and architectural diversity. In this case report we are presenting a case of pleomorphic adenoma of buccal mucosa in a 56 year old male patient who reported to our department with complaint of pain less swelling in the left side cheek region since two years.
Evaluation of the Shear Bond Strength of the Orthodontic Composites Modified with Various Concentrations of TiO2 Nanoparticles: An In vitro Study
Authors: Duvvuri S. N. Reddy , Arafath M. Mohamed , Alla Rama Krishna , Rajasigamani . , Bhaskar V. , Kumaran Kurunji 
Published: February 2023

Aim: This study aimed to evaluate the effect of various concentrations of TiO2 nanoparticles incorporation on the shear bond strength of the two different orthodontic composites.
Materials and Methods: A total of 80 freshly extracted premolars were divided into two groups of 40 teeth each. The extracted teeth in each of these two groups were further divided into four subgroups with ten teeth (n=10) in each, depending on the concentrations of TiO2 NPs (0.0%, 1.0%, 5.0% and 10.0%) in the Transbond XT and Enlight composites. Then the teeth were mounted in cold-cure acrylic resin poured into PVC tubes. The teeth were vertically embedded in acrylic up to the cementoenamel junction (CEJ), and a standard bonding procedure was carried out to bond the brackets using both composites. The shear bond strength was evaluated using a universal testing machine at a crosshead speed of 05mm/minute until the brackets de-bond from the tooth surface. The obtained data were subjected to statistical analysis using Oneway ANOVA and Posthoc tests.
Results: The control groups of both the composites showed more shear bond strength compared to the modified groups. One-way ANOVA showed significant differences (p=0.000) among the groups. Posthoc analysis showed significant differences between the control and modified groups and also between the modified groups in both the composites except between the control and 1.0 wt% and 5.0 and 10.0wt% groups of the Enlight composite.
Conclusion: A decrease in the shear bond strength was observed with an increase in the concentrations of TiO2 nanoparticles in both the composites.
Adaptation of Probationary Employment Contract and Provisions that Regulate it in the Saudi Labor Law: Analytical Comparative Research
Authors: Al-Qarni Mohammed 
Published: February 2023

The importance of Labor Law is becoming increasingly in our current era due to extent of its application, depth of its social impact, increase of man power, appearance specialty of labor judiciary - as an independent judiciary - within courts of public judiciary in the Kingdom of Saudi Arabia, which required developing of legislative rules and keeping up with texts of labor law for development of labor relations, finding suitable and guarantor solutions to rights of parties, due to importance of stability of labor relations in the performance of national economy, the employment contract is considered as cornerstone for creating labor relationship and launching its march, might include a condition of a probation period that enables the parties to relationship or whoever stipulates it to ensure the validity of conclusion of contract for him, due to what the probation condition might contain from conflict of interest, variation of legal and economic status between laborer and employer; which might lead to misuse or circumvention on the law, thus the law has encircled the probation period with a number of conditions and restrictions that guarantee good work with it away from exploitation or abuse while using the right, has decreed up rules to govern the practice and limiting its duration, rules of its extension or repetition, the consequences of end of duration of employment contract concluded between two parties, the Saudi labor law is distinguished from its counterparts in most Arab countries with some rules related to this as indicated in the research, ended with a number of related results using comparative analytical method, benefiting from a number of judicial rulings issued by labor courts in several positions of the research, among its most important results: •	The Saudi Law tended to a condition of a probation for both parties of employment contract – basically or for who stipulate it, the law was clear in defining the terms of contract agreed upon, extending it or repeating the experience. It also tended to legality of ending probation during the period without compensation or end of service gratuity, and it does not enter under arbitrariness of using the right, and is supported provisions of labor judiciary. •	The Saudi Law is distinguished from labor laws in (Egypt and Jordan) by regulating extension of probation period and permissibility of repeating it under certain conditions to guarantee to avoid use of this condition in abusing.
EDUCATION ON THE MANUFACTURE AND APPLICATION OF ORGANIC FERTILIZER IN LUWUK VILLAGE BANTEN
Authors: Yusnita Ria , Anggita Rendi , Sugiharto Purwanto Bayu , Ramadhan Atala Noval Setia , Kusuma Jaka Wijaya , Hamidah Hamidah 
Published: February 2023

Luwuk Village is a village located in the Gunungsari district, Serang regency. The vital agriculture in this village is melinjo. Meanwhile, animal husbandry, buffalo, goats, and chickens are the main attractions in this village. The purpose of this service is to empower the Luwuk Village community to utilize household waste, livestock and agricultural waste that can be used as organic fertilizer. Organic fertilizer is expected to reduce the consumption of chemical fertilizers and increase soil fertility. It can control plant-disturbing organisms to increase the production of melinjo, which is the primary commodity for the people of Luwuk Village. The service method used is in the form of socialization and training in making organic fertilizers. The results achieved in the implementation of the service of the Application of Appropriate Technology for the Manufacture of Organic Fertilizer in Luwuk Village, Gunungsari District, Serang Regency are (1) the community can take advantage of waste into fertilizer;(2) utilization of fertilizer from household organic waste for agriculture; (4) environmental cleanliness from organic waste. The benefits of this service activity are: (1) For lecturers, they can contribute their knowledge and thoughts to the community; (2) For people in the Luwuk Village area, Gunungsari District, Serang Regency, they can produce compost independently and relatively cheaply from the processing results organic waste as a support for the processing of agricultural processes and agricultural products
PELATIHAN PENULISAN ARTIKEL ILMIAH BAGI MAHASISWA PENDIDIKAN JASMANI UNIVERSITAS MULAWARMAN
Authors: Cahyono Didik , Rohadi Muhammad , Nurjamal Nurjamal 
Published: February 2023

The method of this activity is in the form of training and assistance in writing articles and publishing research results to students of the Physical Education Study Program, Faculty of Teacher Training and Education, Mulawarman University. Final semester students are guided to write articles and publish research results in order to improve their abilities and train students to write and publish the results of the scientific work they make. Based on the results and discussion, it can be concluded that students' interest in writing scientific papers is quite high. However, their initial knowledge of scientific papers and writing methods is still lacking. Therefore, this scientific writing training activity is indeed needed to improve students' knowledge and ability to compile scientific papers. Participants experienced an increase in knowledge and writing skills. The results of this service show that this training activity is effective in helping students improve their knowledge and ability to write scientific papers. Training in writing scientific papers can be used as a continuous activity. In addition, currently there are various software for writing references for scientific papers. Therefore, it is necessary to hold training on the use of mandeley software for reference so that writing becomes better
PENDIDIKAN KESEHATAN MENGENAI PENATALAKSANAAN ASI DAN UPAYA MENINGKATKAN PRODUKSI ASI
Authors: Sambas Etty Komariah , Nurliawati Enok 
Published: February 2023

Breastmilk is the first natural food which is the main source of nutrition for babies which contains all the energy and nutrients that babies need in the first months of life. The success of exclusive breastfeeding is influenced by various factors, such as mother's education, commitment to breastfeeding, social support, mother's age, mother's knowledge, place of delivery and culture. Various studies have shown that mother's knowledge regarding breastfeeding management and efforts to increase milk production is in the range of insufficient and sufficient. Therefore, this community service activity was aimed to increase the knowledge and skills of parents and families regarding the management of breast milk and efforts to increase milk production. The method implemented was counseling and demonstration regarding the management of expressed breast milk, breastfeeding techniques and oxytocin massage. The target of the activity was parents and families of newborns who were treated at Perinatology ward at dr. Soekardjo Hospital in Tasikmalaya. The results showed that there was an increase in knowledge scores on the pre and post tests and participants could demonstrate management of expressed breast milk, breastfeeding techniques and oxytocin massage
PrismEXP: gene annotation prediction from stratified gene-gene co-expression matrices
Authors: Lachmann Alexander , Rizzo Kaeli A. , Bartal Alon , Jeon Minji , Clarke Daniel J. B. , Ma’ayan Avi 
Published: February 2023

Background
Gene-gene co-expression correlations measured by mRNA-sequencing (RNA-seq) can be used to predict gene annotations based on the co-variance structure within these data. In our prior work, we showed that uniformly aligned RNA-seq co-expression data from thousands of diverse studies is highly predictive of both gene annotations and protein-protein interactions. However, the performance of the predictions varies depending on whether the gene annotations and interactions are cell type and tissue specific or agnostic. Tissue and cell type-specific gene-gene co-expression data can be useful for making more accurate predictions because many genes perform their functions in unique ways in different cellular contexts. However, identifying the optimal tissues and cell types to partition the global gene-gene co-expression matrix is challenging.

Results
Here we introduce and validate an approach called PRediction of gene Insights from Stratified Mammalian gene co-EXPression (PrismEXP) for improved gene annotation predictions based on RNA-seq gene-gene co-expression data. Using uniformly aligned data from ARCHS4, we apply PrismEXP to predict a wide variety of gene annotations including pathway membership, Gene Ontology terms, as well as human and mouse phenotypes. Predictions made with PrismEXP outperform predictions made with the global cross-tissue co-expression correlation matrix approach on all tested domains, and training using one annotation domain can be used to predict annotations in other domains.

Conclusions
By demonstrating the utility of PrismEXP predictions in multiple use cases we show how PrismEXP can be used to enhance unsupervised machine learning methods to better understand the roles of understudied genes and proteins. To make PrismEXP accessible, it is provided via a user-friendly web interface, a Python package, and an Appyter. AVAILABILITY. The PrismEXP web-based application, with pre-computed PrismEXP predictions, is available from: https://maayanlab.cloud/prismexp; PrismEXP is also available as an Appyter: https://appyters.maayanlab.cloud/PrismEXP/; and as Python package: https://github.com/maayanlab/prismexp.
Ethnobotanical Survey of Medicinal Plants Used against Infertility in the Nyong and So’o Division (Cameroon) and Pro-fertilizing Activities of Mammea africana (Clusiaceae) Aqueous Extract Rats
Authors: Sandrine Mengue Ngadena Yolande , Liliane Foutse Yimta , Bico Zang Christian , Emmanuel Owona Pascal , Lohik Mbolang Nguegan , Claude Bilanda Danielle , Michel Noubom , Jonas Kouamouo , Pierre Kamtchouing , Désiré Dzeufiet Djomeni Paul 
Published: February 2023

Background: World-renowned as primary healthcare, traditional medicine often represents the only therapeutic resource for many communities with very low incomes, although it shows valuable benefits. The objective of this investigation was to evaluate the medicinal plants used to treat infertility in the Nyong & So’o Division (Cameroon) and the effect of Mammea africana, the most commonly used medicinal plant extract, on reproductive parameters in female rats.
Methods: First, a transversal and analytic investigation using semi-structured interviews was conducted on a sample of 22 traditional healers. Secondly, two pharmacological assays were carried out to evaluate M. africana aqueous extract activities in 8-10-week-old female Wistar rats. During 14 days, non-ovariectomized (Novx) mice were given distilled water (DW) at 10 mL/kg and M. africana extract at 40, 80, and 160 mg/kg. In the end, cervical smears were realized, animals were sacrificed, and extract activities were evaluated on reproductive parameters. The estrogenic activities of M. africana extract were assessed on estrogenic-dependent tissues per os in ovariectomized (Ovx) rats in the second assay. They received respectively distilled water (DW), estradiol valerate (E2V) at 1 mg/kg, and the extract at the aforesaid doses, and 3 groups were co-treated with E2V (0.75 mg/kg) and the extract. A sham-operated group received DW
Results: Ethnobotanical investigation revealed that 20 species of plant belonging to 13 different families are used to treat infertility. Mammea africana was the most used plant and its extract at 80 mg/kg aqueous extract induced a significant increase (p <0.001) of FSH, LH, and estradiol in Novx rats compared to control. Furthermore, the extract induced the maturation of ovarian follicles. M. africana extract exhibited also estrogenic activities in Ovx rats. Indeed, M. africana aqueous extract induced the formation of stratum corneum in the vagina of Ovx rats. E2V activities at 0.75 mg/kg were maximized by M. africana extract.
Conclusion: To sum up, many species are used in the Nyong & So’o Division to manage reproductive failure. Among them, Mammea africana is the most commonly used and possesses estrogenic-like activities.
Association of Cardiovascular Health With Life Expectancy Free of Cardiovascular Disease, Diabetes, Cancer, and Dementia in UK Adults
Authors: Wang Xuan , Ma Hao , Li Xiang , Heianza Yoriko , Manson JoAnn E. , Franco Oscar H. , Qi Lu 
Published: February 2023

ImportanceThe average life expectancy has increased substantially in the past few decades in most industrialized countries; however, not all of the increased life expectancy is being spent in optimal health, especially among individuals with low socioeconomic status.ObjectiveTo quantify the associations between levels of cardiovascular health (CVH), estimated by the American Heart Association’s Life’s Essential 8 (LE8) metrics, with life expectancy free of major chronic disease, including cardiovascular disease (CVD), diabetes, cancer, and dementia, in UK adults.Design, Setting, and ParticipantsThis cohort study included 135 199 adults in the UK Biobank study who were initially free of major chronic disease and had complete data on LE8 metrics. Data analyses were performed in August 2022.ExposuresCardiovascular health levels, as estimated by LE8 score. The LE8 score, which consists of 8 components: (1) diet, (2) physical activity, (3) tobacco/nicotine exposure, (4) sleep, (5) body mass index, (6) non–high-density lipoprotein cholesterol, (7) blood glucose, and (8) blood pressure. The CVH level was evaluated at baseline and categorized into low (LE8 score &amp;lt;50), moderate (LE8 score ≥50 but &amp;lt;80), and high (LE8 score ≥80) levels.Main Outcomes and MeasuresThe primary outcome was the life expectancy free of 4 major chronic diseases (CVD, diabetes, cancer, and dementia).ResultsOf the 135 199 adults (44.7% men; mean [SD] age, 55.4 [7.9] years) included in the study, a total of 4712, 48 955, and 6748 men had low, moderate, and high CVH levels, respectively, and the corresponding numbers for women were 3661, 52 192, and 18 931. At age 50 years, the estimated disease-free years were 21.5 (95% CI, 21.0-22.0), 25.5 (95% CI, 25.4-25.6), and 28.4 (95% CI, 27.8-29.0) for men with low, moderate, and high CVH levels, respectively; the corresponding estimated disease-free years at age 50 years for women were 24.2 (95% CI, 23.5-24.8), 30.5 (95% CI, 30.4-30.6), and 33.6 (95% CI, 33.1-34.0). Equivalently, men with moderate or high CVH levels lived on average 4.0 (95% CI, 3.4-4.5) or 6.9 (95% CI, 6.1-7.7) longer years free of chronic disease, respectively, at age 50 years, compared with men with low CVH levels. The corresponding longer years lived free of disease for women were 6.3 (95% CI, 5.6-7.0) or 9.4 (95% CI, 8.5-10.2). For participants with high CVH level, there was not a statistically significant difference in disease-free life expectancy between participants with low and other socioeconomic status.Conclusions and RelevanceIn this cohort study, a high level of CVH, evaluated using the LE8 metrics, was associated with longer life expectancy free of major chronic diseases and may contribute to narrowing socioeconomic health inequalities in both men and women.
Therapeutic radiation beam output and energy variation across clinics, technologies, and time
Authors: Zaini Mehran Miron , Fagerstrom Jessica M. , Marshall Edward I. , Hedrick Kathryn M. , Zaks Daniel , Tran Hung , Fitzgerald Trevor M. 
Published: February 2023

AbstractOver the past several decades, a medical physics service group covering 35 clinical sites has provided routine monthly output and energy quality assurance for over 75 linear accelerators. Based on the geographical spread of these clinics and the large number of physicists involved in data acquisition, a systematic calibration procedure was established to ensure uniformity. A consistent measurement geometry and data collection technique is used across all machines for every calendar month, using a standardized set of acrylic slabs. Charge readings in acrylic phantoms are linked to AAPM's TG‐51 formalism via a parameter denoted kacrylic, used to convert raw charge readings to machine output values. Statistical analyses of energy ratios and kacrylic values are presented. Employing the kacrylic concept with a uniform measurement geometry of similar acrylic blocks was found to be a reproducible and simple way of referencing a calibration completed in water under reference conditions and comparing to other machines, with the ability to alert physicists of outliers.
Perfluoro Macrocyclic Ether as an Ambifunctional Additive for High‐Performance SiO and Nickel 88%‐Based High‐Energy Li‐ion Battery
Authors: Oh Min‐Geun , Kwak Sehyun , An Kihun , Tran Yen Hai Thi , Kang Dong Guk , Park Seong Jun , Lim Guntae , Kim Koeun , Lee Yoon Sung , Song Seung‐Wan 
Published: February 2023

AbstractState‐of‐the‐art lithium (Li)‐ion batteries employ silicon anode active material at a limited fraction while strongly relying on fluoroethylene carbonate (FEC) electrolyte additive exceeding 10 wt.% to enable stable cycling. The swelling issue of silicon in the aspect of solid electrolyte interphase (SEI) instability and a risk of safety hazards and high manufacturing cost due to FEC has motivated the authors to design a well‐working fluorinated additive substitute. High‐capacity cells employing nickel‐rich oxide cathode are pursued by operating at > 4.2 V versus Li/Li+, for which anodic stability of electrolyte is required. Herein, a highly effective new ambifunctional additive of icosafluoro‐15‐crown 5‐ether is proposed at a little fraction of 0.4 wt.% for the stabilized interfaces and reduced swelling of high capacity (3.5 mAh cm−2) 5 wt.% SiO‐graphite anode and LiNi0.88Co0.08Mn0.04O2 cathode. Utilizing together with a lowered fraction of FEC, reversible long 300 cycles at 4.35 V and 1 C (225 mA g−1) are achieved. Material characterization results reveal that such stabilization is derived from the surface passivation of both anode and cathode with perfluoro ether, LiF, and LixPFy species. The present study gives insight into electrolyte formulation design with lower cost and both‐side stabilization strategies for silicon and nickel‐rich active materials and their interfaces.
Electrocapacitive Deionization: Mechanisms, Electrodes, and Cell Designs
Authors: Sun Kaige , Tebyetekerwa Mike , Wang Chao , Wang Xianfen , Zhang Xiwang , Zhao Xiu Song 
Published: February 2023

AbstractCapacitive deionization (CDI) is an emerging water desalination technology for removing different ionic species from water, which is based on electric charge compensation by these charged species. CDI is becoming popular because it is more energy‐efficient and cost‐effective than other technologies, such as reverse osmosis and distillation, specifically in dealing with brackish water having low or moderate salt concentrations. Over the past decade, the CDI research field has witnessed significant advances in the used electrode materials, cell architectures, and associated mechanisms for desalination applications. This review article first discusses ion storage/removal mechanisms in carbon and Faradaic materials aided by advanced in situ analysis techniques and computations. It then summarizes research progress toward electrode materials in terms of structure, surface chemistry, and composition. More still, it discusses CDI cell architectures by highlighting their different cell design concepts. Finally, current challenges and future research directions are summarized to provide guidelines for future CDI research.
4D Printed Shape Memory Anastomosis Ring with Controllable Shape Transformation and Degradation
Authors: Peng Wenjun , Yin Jie , Zhang Xianming , Shi Yunpeng , Che Gang , Zhao Qian , Liu Jian 
Published: February 2023

AbstractBiofragmentable anastomosis ring (BAR) is an ideal sutureless alternative for intestinal connection that is frequently demanded in colonic surgery. However, it is challenging to insert a bulky BAR into the soft and slippery intestine. Here 4D printing of an anastomosis ring with shape memory capability is presented via fused deposition modeling (FDM) 3D printing. The shape memory anastomosis ring can recover from a compressed shape that facilitates the insertion to the permanent shape for connection and supporting. Degradation kinetics is tuned by controlling the blending composition of polylactic acid and poly(lactic‐co‐glycolic acid), so that the device can be excreted after the intestine healing. The shape recovery temperature is adjusted to 50 °C that the human body can withstand for a while. Grid structure and hook lock are designed and printed to guarantee dimension reduction upon programming and stable connection after shape recovery, respectively. A conceptual anastomotic operation shows the advantages and prospects of shape transformation. The 4D printing strategy may promote intestinal anastomosis development and inspire more opportunities for minimally invasive medical surgery.