bluuebunny/crossref_metadata_2025_split huggingface dataset:
Leadership characteristics for implementation and sustainability of quality: an exploratory study and directions for further research
Authors: Laureani Alessandro , Antony Jiju , Ramadan Mariam Ali , Al Dhaheri Maha Khalifa , Fundin Anders , Sörqvist Lars 
Published: September 2023

PurposeThis qualitative study aims to explore the concept of organisational leadership in the context of Quality Management deployments across a variety of business organisations, particularly focusing on the possible relationships between leadership approaches during the implementation and sustaining phases of Quality Management.Design/methodology/approachThe study is based on one-to-one semi-structured virtual interviews with leaders in the quality field.FindingsFour themes (Customers, Leadership, Quality Culture and Sustainability of Quality) emerged from the post-interview data analysis, illustrating the critical role of Leadership in the successful deployment and sustainment of Quality Management and identifying the leadership traits that are most conducive to successful organisational deployments.Originality/valueAlthough some of these leadership traits are described in the wider leadership literature as belonging to one or more different leadership styles, there is no existing style of leadership that comprehends all the characteristics; thus, the need for a new leadership paradigm is this paper's theoretical contribution to the literature.
When China strikes: Quantifying Australian companies' stock price responses to China's trade restrictions
Authors: Xiong Tao , Zhang Wendong , Zhao Fangxiao 
Published: September 2023

AbstractIn early 2020, China, Australia's top export market, unilaterally imposed trade restrictions on Australian barley, beef, coal, cotton, timber, copper and wine. However, convincing evidence regarding the effects of such trade restrictions on firms is scarce. Leveraging data on daily stock returns from 20 listed Australian and 32 listed Chinese firms that produce the restricted commodities, we provide the first systematic analysis of the firm‐level economic impacts of China's trade restrictions on Australian and Chinese firms. We find significant adverse effects on Australian firms' stock returns, leading to almost 20% loss within 10 trading days; however, most firms' stock returns immediately rebounded. In contrast, Chinese firms usually saw significant positive stock returns, leading to almost 30% gains, and the positive abnormal returns continuously increased within 10 trading days. Media coverage and trade dependence substantially impact Australian and Chinese firms' stock returns—industries with stronger trade dependence on China saw greater losses in Australian firms' stock returns. Our results suggest that tradereallocationanddeflectionare two effective mitigation mechanisms for Australian exporters facing China's trade restrictions.
Estimation of green mining GDP for 40 countries
Authors: Mardones Cristian 
Published: September 2023

AbstractMining is an important economic activity and a source of fiscal resources in many countries. However, its contribution to GDP does not reflect the depletion of non‐renewable natural resources and the environmental damage caused. For this reason, methodologies have emerged that allow correcting the traditional GDP through the so‐called green GDP. The main objective of this study is to use the same method, data from the same source, and economic valuation of the same components to compare the green GDP among countries and its evolution over time. Specifically, the green mining GDP (in millions of dollars for the year 2014) is estimated for 40 countries, valuing the depreciation of natural capital and the environmental damage associated with global and local air pollutants emissions. The results show that the green mining GDP represents only 24.4% of the mining GDP in all the countries studied from 2000 to 2014. However, the indicator is quite heterogeneous among countries and years analyzed. For example, 25 countries have had a positive green mining GDP in all years, and 10 countries have achieved it in recent years. Thus, it is concluded that there is ample space to develop more sustainable mining in many countries.
QD‐based fluorescent nanosensors: Production methods, optoelectronic properties, and recent food applications
Authors: Jia Zhixin , Shi Ce , Yang Xinting , Zhang Jiaran , Sun Xia , Guo Yemin , Ying Xiaoguo 
Published: September 2023

AbstractFood quality and safety are crucial public health concerns with global significance. In recent years, a series of fluorescence detection technologies have been widely used in the detection/monitoring of food quality and safety. Due to the advantages of wide detection range, high sensitivity, convenient and fast detection, and strong specificity, quantum dot (QD)‐based fluorescent nanosensors have emerged as preferred candidates for food quality and safety analysis. In this comprehensive review, several common types of QD production methods are introduced, including colloidal synthesis, self‐assembly, plasma synthesis, viral assembly, electrochemical assembly, and heavy‐metal‐free synthesis. The optoelectronic properties of QDs are described in detail at the electronic level, and the effect of food matrices on QDs was summarized. Recent advancements in the field of QD‐based fluorescent nanosensors for trace level detection and monitoring of volatile components, heavy metal ions, food additives, pesticide residues, veterinary‐drug residues, other chemical components, mycotoxins, foodborne pathogens, humidity, and temperature are also thoroughly summarized. Moreover, we discuss the limitations of the QD‐based fluorescent nanosensors and present the challenges and future prospects for developing QD‐based fluorescent nanosensors. As shown by numerous publications in the field, QD sensors have the advantages of strong anti‐interference ability, convenient and quick operation, good linear response, and wide detection range. However, the reported assays are laboratory‐focused and have not been industrialized and commercialized. Promising research needs to examine the potential applications of bionanotechnology in QD‐based fluorescent nanosensors, and focus on the development of smart packaging films, labeled test strips, and portable kits‐based sensors.
Washed microbiota transplantation for Clostridioides difficile infection: A national multicenter real‐world study
Authors: Wu Xia , Ai Ru Jun , Xu Jie , Wen Quan , Pan Hua Qin , Zhang Zhi Hua , Ning Wang , Fang Ying , Ding Da Fa , Wang Quan , Han Shuang , Liu Xiao , Wu Mei , Jia Zhen Yu , Jia Song , Lin Tao , Cui Bo Ta , Nie Yong Zhan , Wang Xin , Zhang Fa Ming 
Published: September 2023

ObjectivesFecal microbiota transplantation (FMT) has been recommended for the treatment of recurrent Clostridioides difficile infection (CDI). We aimed to evaluate the therapeutic efficacy and safety of washed microbiota transplantation (WMT), a new method of FMT, for CDI across various medical settings.MethodsThis multicenter real‐world cohort study included CDI patients undergoing WMT. The primary outcome was the clinical cure rate of CDI within 8 weeks after WMT. Secondary outcomes included the CDI recurrence rate and reduction in total abdominal symptom score (TASS) during the follow‐up period. Adverse events related to WMT were recorded.ResultsAltogether 90.7% (49/54) of CDI patients achieved clinical cure after treated with WMT. The cure rate was 83.3% for cases with severe and complicated CDI (ScCDI) (n = 30) and 100% for non‐ScCDI cases (n = 24) (P = 0.059). No difference was observed in the clinical cure rate between patients with first and recurrent CDI (91.9% vs 88.2%, P = 0.645). One week post‐WMT, TASS showed a remarkable decrease compared to that at baseline (P < 0.001). Totally, 8.2% (4/49) of patients suffered CDI recurrence during the follow‐up period. A WHO performance score of 4, age ≥65 years, higher TASS score, and higher Charlson comorbidity index score were potential risk factors for efficacy (P = 0.018, 0.03, 0.01, 0.034, respectively). Four (3.8%) transient adverse events related to WMT were observed.ConclusionsThis study emphasizes the attractive value of WMT for CDI. Early WMT may be recommended for CDI, especially for those in serious condition or with complex comorbidities.Trial registrationClinicalTrials.gov, no. NCT03895593 (registered on 27 March 2019).
Effect and mechanism of microRNAs on various diabetic wound local cells
Authors: Li Hongjie , Jing Shengyu , Xu Hongbo 
Published: September 2023

AbstractThe difficulty of wound healing in diabetes mellitus has long been regarded as a thorny problem in the medical field. One of the important reasons is the abnormal function of wound‐related cells. A large number of recent studies have shown that microRNA (miR), a noncoding RNA that exists in eukaryotic cells, is closely linked to the functions of various cells in diabetic wound, and ultimately affects the healing of wound. This paper establishes for the first time the connection between miR and wound healing from the cellular perspective and summarizes the effects of various miRs on one or more kinds of wound cells, including their targets and related mechanisms. The abnormal expression of miRs in the wound has certain value for the early diagnosis of diabetic wounds. Moreover, it seems that correcting miRs that are abnormal expressed in the wound or artificially adding miRs that can promote wound healing has an essential therapeutic value.
Observational longitudinal study to assess the outcome of patients with idiopathic inflammatory myositis using validated tools
Authors: Shukla Anuj , Gaur Priyanka 
Published: September 2023

AbstractIntroductionThere have been major changes in the classification and treatment of patients with idiopathic inflammatory myositis (IIM) in the last 2 decades. A major challenge is to identify the parameters that can affect the outcome and prognosis of these patients. Here, we have longitudinally followed a well‐characterized cohort of IIM patients in a rheumatology center and reported the outcome using the validated tools.MethodPatients with a clinical diagnosis of IIM and a follow‐up duration of greater than 2 years were prospectively included in the study. The duration of the study was 6 years: July 2016–July 2022. Clinical details and follow‐up were recorded using pro‐formas and outcomes were noted using validated tools. Ethics approval and written informed consent were taken.ResultsForty patients had a clinical diagnosis of IIM. Mean follow‐up duration was 43.8 (15) months. Out of 40 patients, 32 (80%) achieved remission (8 patients each were off corticosteroid and off treatment for >6 months), 5 (12%) expired and 3 (8%) had active disease. Disease course was non‐relapsing in 22/35 (73%) patients. Mean manual muscle testing‐8 score (n = 29) and myositis disease activity assessment tool score (n = 35) at the final visit were 75.6 (6.8) and 0.048 (0.07) respectively. Thirteen patients had damage (37%). Patients with disease duration >1 year at the time of presentation were more likely to develop chronic‐continuous disease course (P = .023, odds ratio [OR] = 7.6), more frequently required second‐line or third‐line immunosuppression (P = .001, OR = 24) with higher myositis damage index score (p = .0002, OR = 47).ConclusionsIIM patients had good outcomes with the majority achieving remission and near‐complete muscle recovery. However, the patients presenting late to the rheumatologists were more likely to have smoldering disease, more immunosuppressive medicines, and greater accumulated damage.
Causal relationship between sex hormone‐binding globulin and major depression: A Mendelian randomization study
Authors: Zhu Haohao , Sun Yifan , Guo Shuaiyi , Zhou Qin , Jiang Ying , Shen Yuan , Zhou Zhenhe , Du Zhiqiang , Zhou Hongliang 
Published: September 2023

AbstractObjectiveThis study aimed to explore the causal relationship between sex hormone‐binding globulin (SHBG) and major depression using two‐sample Mendelian randomization (MR) studies.MethodsBased on the genome‐wide association study (GWAS) summary data of SHBG and major depression in the European population, which included 214,989 female SHBG samples, 185,221 male SHBG samples, and 500,199 major depression samples, we used genetic factors as instrumental variables to conduct two‐sample MR analyses. We used methods including inverse variance weighted (IVW), weighted median, weighted mode, and MR Egger to evaluate the bidirectional causal relationship between SHBG and major depression.ResultsThe results showed that there was a causal relationship between female SHBG and major depression, which was positively correlated. The ORs were 1.056 (95% CI: 1.005–1.109, p = 0.031) for the weighted median and 1.067 (95% CI: 1.012–1.126, p = 0.021) for the weighted mode. There was no significant effect of male SHBG on major depression (p > 0.05), and there was no significant effect of major depression on female SHBG (p > 0.05). Major depression was negatively correlated with male SHBG, indicating that major depression could lead to a decrease in male SHBG. The OR was 0.954 (95% CI: 0.916–0.993, p = 0.023) for IVW.ConclusionFemale SHBG was positively correlated with the risk of major depression, however, major depression was found to be negatively correlated with serum SHBG levels in men, indicating that SHBG plays distinct roles in patients with major depression of different genders.
Role of oestrous cycle and orbitofrontal cortex in oxycodone seeking after 15‐day abstinence in female rats
Authors: Olaniran Adedayo , Altshuler Rachel D. , Burke Megan A. M. , Lin Hongyu , Firlie Julia , Linshitz Ilan , Li Xuan 
Published: September 2023

AbstractRelapse to oxycodone seeking progressively increases after abstinence in rats, a phenomenon termed incubation of oxycodone craving. We have previously shown that the orbitofrontal cortex (OFC) plays a critical role in incubation of oxycodone craving in male rats. Here, we examined the effect of oestrous cycle on incubated oxycodone seeking in female rats, and whether the critical role of OFC in incubated oxycodone seeking generalizes to female rats. We first assessed oxycodone self‐administration and incubated oxycodone seeking on abstinence day 15 across the oestrous cycle. Next, we determined the effect of chemogenetic inactivation of OFC by JHU37160 (J60), a novel agonist for Designer Receptors Exclusively Activated by Designer Drugs (DREADDs), on incubated oxycodone seeking on abstinence day 15. Finally, we determined the effect of J60 alone on incubated oxycodone seeking on abstinence day 15. We found no difference in oxycodone intake across oestrus, pro‐oestrus, and metoestrus stages during oxycodone self‐administration training. Incubated oxycodone seeking was also similar between nonoestrus and oestrus female rats. Moreover, chemogenetic inactivation of OFC by J60 decreased incubated oxycodone seeking on abstinence day 15, while J60 alone had no effect on incubated oxycodone seeking in no‐DREADD control rats. Taken together, results here show that the oestrous cycle has no effect on oxycodone intake and incubated oxycodone seeking in female rats under our experimental conditions. Furthermore, consistent with our previous findings in male rats, results here show that OFC also plays a critical role in incubated oxycodone seeking in female rats.
Basophil activation test as predictor of severity and threshold of allergic reactions to egg
Authors: Radulovic Suzana , Foong Ru‐Xin , Bartha Irene , Marques‐Mejias Andreina , Krawiec Marta , Kwok Matthew , Jama Zainab , Harrison Faye , Ricci Cristian , Lack Gideon , Du Toit George , Santos Alexandra F. 
Published: September 2023

AbstractBackgroundIdentifying patients at risk of severe allergic reactions and/or low threshold of reactivity is very important, particularly for staple foods like egg.MethodsOne hundred and fifty children underwent double‐blind placebo‐controlled food challenge (DBPCFC) to baked egg (BE), skin prick testing and blood collection for serology and basophil activation test (BAT). Patients who passed BE DBPCFC underwent loosely cooked egg (LCE) DBPCFC. Severity of allergic reactions was classified following Practall guidelines and threshold dose was determined during DBPCFC.ResultsSixty out of 150 (40%) children reacted to BE and 16 out of 77 (21%) to LCE on DBPCFC. Considering DBPCFC to BE, 23 children (38%) had severe reactions and 33 (55%) reacted to 0.13 g or less of egg protein (low threshold group). Two children (2 out of 16 = 12%) had severe reactions to LCE. Demographic, clinical and most immunological features were not significantly different between severe/non‐severe BE reactors or low/high threshold groups. Severe BE reactors had higher ovomucoid‐sIgE (p = .009) and higher BAT to BE (p = .001). Patients with lower threshold to BE had higher IgE‐specific activity (p = .027) and BAT to egg (p = .007) but lower severity score (p = .008). Optimal cut‐offs for ovomucoid‐sIgE had 100% sensitivity, 35% specificity and 60% accuracy and for BAT 76% sensitivity, 74% specificity and 75% accuracy to identify BE severe reactors. Optimal cut‐offs for specific activity had 70% sensitivity, 68% specificity and 69% accuracy and for BAT 70% sensitivity, 72% specificity and 71% accuracy to identify low threshold patients.ConclusionsBAT was the best biomarker to predict severity and threshold of allergic reactions to BE and can be useful when making decisions about management of egg allergy.
Incommunicable: Decolonizing perspectives on language and health
Authors: Briggs Charles L. 
Published: September 2023

AbstractThis article fosters a new relationship between linguistic and medical anthropology by decolonizing foundational conceptions of language and health. It reintroduces John Locke as a philosopher‐physician who used diagnosis of language disorders to impose a regime of communicability—reducing language to exchanging transparent, stable, purely referential signs. By deeming white, elite, able‐bodied European men alone capable of enacting this self‐help program, he connected communicability to whiteness and turned it into a means of evaluating and subordinating all others. Communicability also enabled him to shape how physicians produce knowledge in empiricist, atheoretical, observational fashion. I then trace physician‐philosopher Frantz Fanon's critique of how colonialism denies communicability to racialized subjects. Fanon's analysis of colonial medicine shows how clinical encounters can produce incommunicable subjects. Given that constructions of communicability have become highly visible features of medical education and practice and social‐scientific research on it, the article extends Fanon's analysis of physician‐patient communication more generally to ask if contemporary efforts to regiment clinical interactions and assess the communicable success of patients and doctors alike turn them into sites of incommunicability—assessments of communicable failure—for both parties. The article ends by imagining worlds beyond the oppressive weight of communicability and the stigma of incommunicability.
Fear the Native woman: Femininity, food, and power in the sixteenth‐century North Carolina Piedmont
Authors: Briggs Rachel V. , Rodning Christopher B. , Beck Robin A. , Moore David G. 
Published: September 2023

AbstractNative women in Indigenous‐Western colonial entanglements are often portrayed as passive agents with little transformative social power in an otherwise dynamic landscape. However, Native women throughout the European colonial world many times controlled the most important resource required by European colonists: the knowledge and materials necessary to transform raw materials into “food.” Their control over this invaluable resource provided Native women with avenues of power both within their own societies and in European colonies. Here, we explore constructions and perceptions of Native women's power during the period of sixteenth‐century Spanish expeditions into the Carolina Piedmont and mountains by reviewing documentary data from entradas led by Hernando de Soto and Juan Pardo, as well as archaeological data from the Indigenous town of Joara and the Spanish colonial outpost of Cuenca and Fort San Juan at the Berry site (31BK22), located near Morganton, North Carolina. Employing an Indigenous feminist framework, we argue that the power vested in Native women through their own societies, as well as by Spaniards through their dependence on them for survival, provided Native women with far greater agency and power in entanglements with Spanish colonists, and interactions with European colonists more broadly, than previously recognized.
Thrombosis incidence in major paediatric burns
Authors: Kimball Ashlee , Gibson Edward , Quinn Linda , Cooksey Rebecca , Molony Darren , Lodge Michelle , Carney Bernard , Jeeves Amy 
Published: September 2023

AbstractBackgroundMajor burns are associated with multiple risk factors for thrombosis such as decreased mobilization and systemic inflammation. It is unclear if these factors are offset by the inherent lower thrombosis risk in the paediatric patient. As such there is no consensus on thromboprophylaxis for paediatric burns patients, in contrast to this being a mainstay of treatment in the adult population. This retrospective cohort study examines the incidence of, and risk factors for, thrombotic events in major paediatric burns with a view to establish guidelines for prevention.MethodReview of major paediatric burns, defined as % total body surface area (%TBSA) ≥30%, at the Adelaide Women's and Children's Hospital (WCH) over a 16‐year period. Coding data and the local burns database were used to identify participants with subsequent review of case files.ResultsOf the cohort (n = 23), six cases (26%) were complicated by thrombotic events. These patients had the most extensive burns averaging 68.5% TBSA, longer PICU admissions and associated interventions. These data points were more than doubled in the cohort diagnosed with a thrombus. Of the six events, five were secondary to central venous catheters (CVC) and one deep venous thrombosis (DVT) to the left calf.ConclusionThe incidence of thrombotic events in our study was significant albeit in a small population. There is a strong association between large %TBSA and thrombus, with clots mostly forming around CVCs. While further research is required, this study demonstrates screening and targeted thromboprophylaxis may be required for major paediatric burns.