bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interactive training in the organization of independent work of students in universities of Kazakhstan
Authors: Nygyzbayeva R. Zh. , Imanbayeva G. N. , Tussupbekova M. M. , Stabayeva L. M. , Abiyeva S. S. 
Published: September 2023

The purpose of the article is to improve the methods and forms of teaching students, the formation of a scientifically based unified system. The training of qualified specialists at the university requires the use of new forms and methods of teaching. It is necessary to identify and improve the ways of education based on innovative pedagogical technologies. One of the new tasks of state strategies remains to increase the requirements for training specialists in the international education market and the active introduction of modern innovative technologies into the educational process, support for the promotion of scientific technology in higher education and medicine. The introduction of interactive learning technologies into the educational process, including the use of remote technologies with video content, the strengthening of the material and technical base for medical and technical specialties, the increase in the number of electronic reading rooms, the organization of research work, continues widely.It should be noted that modern innovative technologies are widely used not only in the educational process, but also in the training of competitive young professionals who are in high demand on the international market. Effective ways of education are determined at the level of knowledge using various methods. Today, along with the basic teaching methods formed in the learning process, new methods are often used. The assessment of the level of knowledge of students is determined by various teaching methods.
Implementation of the educational program «Pharmaceutical cosmetology» together with the partner university
Authors: Sakipova Z. B. , Ustenova G. O. , Raganina K. T. , Zhakipbekov K. S. 
Published: September 2023

The School of Pharmacy of the Asfendiyarov Kazakh National Medical University implements joint educatioal programs «Cosmetology pharmaceutical», which is part of the group of educational programs «Pharmacy».To optimize the educational process, a comparative analysis of the curricula of the SOP of the leading universities of the far and near abroad was carried out. As a result of the analysis, educational programs were compiled in the areas of training, a cycle of elective disciplines with a partner university – the University of Information Technology and Management in Rzeszow, Poland.The structure and content of the joint educational program is developed on the basis of a student-centered approach to learning, developed with the participation of students and other stakeholders.The bachelor's degree program is at least 180-240 ECTS credits; the joint master's program is at least 90- 120 ECTS credits and should not be less than 60 ECTS credits at the second level of the cycle (credit ranges according to FQ-EHEA).The joint educational program has mechanisms for monitoring the workload and the average time for completion of the program.
PHARMACOGNOSTIC, PHYSICOCHEMICAL AND PHYTOCHEMICAL EVALUATION OF RHIZOME OF PARASITIC HERB ALECTRA THOMSONII HOOK. F.
Authors: Dr Pravin Ajabsing Theng  
Published: September 2023

Alectra thomsonii is a rare medicinal plant commonly known as “Nirguntha” that belongs to the family Scrophulariaceae. The microscopic evaluation of the rhizome was done by taking the appropriate section of the rhizome. In organoleptic evaluation, the prepared rhizome powder was brown in color with a pungent odor, smooth texture, and bitter in taste. Powder microscopic evaluation revealed different characteristics such as spiral, scalariform, pitted, and reticulated vessels as well as lignified cork cells and starch grains. Physicochemical parameters such as foreign matter, Moisture content, Loss on drying, total ash, acid-insoluble ash, and water-soluble ash were determined. Qualitative phytochemical evaluation of the rhizome showed the presence of alkaloids, carbohydrates, glycosides, flavonoids, proteins, and phenolic compounds etc. The aim of the study is to evaluate parameter to determine the quality of the Alectra thomsonii rhizome.
Isolation and Molecular Characterization of Chromium Reducing Haloalkaliphilic Bacteria from Alkaline Lonar Lake
Authors: Jadhav Dr. Amol Santosh Jadhav 
Published: September 2023

Heavy metals generated mainly through many anthropogenic processes, and some natural processes have been a great environmental challenge and continued to be the concern of many researchers and environmental scientists. This is mainly due to their highest toxicity even at a minimum concentration as they are nonbiodegradable and can persist in the aquatic and terrestrial environments for long periods. Chromium ions, especially hexavalent ions (Cr(VI)) generated through the different industrial process such as tanneries, metallurgical, petroleum, refractory, oil well drilling, electroplating, mining, textile, pulp and paper industries, are among toxic heavy metal ions, which pose toxic effects to human, plants, microorganisms, and aquatic lives.The present study deals with isolation and molecular characterization of bacteria from alkaline lonar crater, having ability to survive and remediate the chromium. In the present study, 26 bacterial isolates were obtained from twelve samples of water, matt and sediment collected from Lonar Lake. Among these isolates, a well characterized isolate ASJ 21 was subjected for molecular characterization on the basis of 16S rRNA gene sequencing. On the basis of 16S rRNA gene sequencing, isolate ASJ 21 was identified as Lysinibacillus mangiferihumi. The chromium remediation ability of Lysinibacillus mangiferihumi was studied spectrophotometrically by using Di-phenyl carbazide assay and the study revealed that the isolate Lysinibacillus mangiferihumi reduced 88% of chromium and rate reduction of chromium was found to be 0.916 µg/mL after 96h of incubation period, showing the ability of microorganisms to tolerate the chromium concentration at alkaline pH and potential to remediate and detoxify hexavalent Chromium (VI) to trivalent Chromium (III) as well.
Application of the K-Means Algorithm in Traffic Violations In Langkat District (Case Study: Langkat Police)
Authors: Sari Elisa Puspita , Maulita Yani , Syari Milli Alfhi 
Published: September 2023

Aktivitas masyarakat berhubungan dengan lalu lintas dan masyarakat lebih memilih menggunakan kendaraan. Rendahnya edukasi serta minim pemahaman tentang peraturan lalu lintas menyebabkan banyak pelanggaran. Meningkatnya jumlah pelanggar lalu lintas menyebabkan meningkatnya data pelanggaran lalu lintas. Banyaknya data pelanggaran lalu lintas menyebabkan terjadinya penumpukan data pada instansi. Maka diperlukan suatu pengolahan data dengan data mining menggunakan Algoritma K-Means. Hasil penelitian diketahui kelompok data pelanggaran lalu lintas yang memiliki kelompok paling tinggi dan paling sering muncul saat diproses yaitu usia 17-25 tahun, dengan kendaraan Honda Vario 150 dan bukti pelanggaran SIM dan STNK. Hasil pengujian 3 cluster dari 502 data pelanggaran diketahui yaitu cluster 1 kelompok data pelanggaran lalu lintas usia 26-45 tahun jenis kendaraan Honda CBR 250 dan bukti pelanggaran SIM dan STNK. Cluster 2 kelompok data pelanggaran lalu lintas usia 26-45 tahun dengan jenis kendaraan Suzuki Nex dengan bukti pelanggaran SIM dan boncengan lebih dari 1. Cluster 3 yaitu kelompok data pelanggaran lalu lintas usia 17-25 tahun, dengan jenis kendaraan Honda Vario 150 dan bukti pelanggaran SIM.
กลยุทธ์การสื่อสารการตลาดด้วยความเชื่อมูเตลูในยุคดิจิทัล
Authors: ศรีมีธรรม ศุภจิรา , เศรษฐจิตร รัตนวดี 
Published: September 2023

บทความนี้มีวัตถุประสงค์เพื่ออธิบายการเปลี่ยนแปลงและวิวัฒนาการเกี่ยวกับสังคมไทยและความเชื่อในยุคดิจิทัลที่เชื่อมโยงกับธุรกิจในยุคปัจจุบัน โดยรวบรวมข้อมูลจากแนวคิดการตลาด การสื่อสารการตลาด เทคโนโลยี และการเติบโตของธุรกิจที่เข้าสู่ยุคการตลาดดิจิทัล ผลการศึกษา พบว่า การตลาดมีการปรับเปลี่ยนไปตามวิถีชีวิตใหม่ของผู้บริโภค จากส่วนประสมทางการตลาดที่ให้ความสำคัญกับกลยุทธ์การสื่อสารการตลาด การตลาดแบบ 4E Marketing และการตลาดแบบ Sensory Marketing ซึ่งเป็นกลยุทธ์การตลาดที่ใช้ดึงดูดและกระตุ้นความสนใจให้ผู้บริโภคซื้อสินค้าและบริการเพื่อให้ธุรกิจดำเนินต่อไปได้ในยุคดิจิทัล ปัจจุบันธุรกิจใช้การสื่อสารการตลาดผสมผสานกับความเชื่อและความศรัทธาจนเกิดเป็นแนวทางการตลาดแบบที่เรียกว่า “การสื่อสารการตลาดมูเตลู” การนำกลยุทธ์การสื่อสารการตลาดมาประยุกต์ใช้กับสินค้าและบริการสะท้อนถึงวิวัฒนาการและการเปลี่ยนแปลงความเชื่อมูเตลูที่เชื่อมโยงกับธุรกิจผ่านวิธีการสื่อสารต่าง ๆ เช่น การใช้ผู้ที่มีอิทธิพลทางความคิด บุคคลที่มีชื่อเสียง และนักแสดงที่มีความเชื่อเกี่ยวกับมูเตลูแนะนำเครื่องรางที่ตนเองครอบครองเพื่อส่งเสริมการขายสินค้า เช่น เบอร์มงคล วอลล์เปเปอร์โทรศัพท์มือถือ สร้อยข้อมือ เสื้อสีมงคล ตลอดจนการดูดวงผ่านสื่อสังคมออนไลน์ ดังนั้น การสื่อสารการตลาดแบบมูเตลูจึงเป็นกลยุทธ์ที่น่าสนใจในยุคดิจิทัลที่แสดงถึงการปรับตัวของธุรกิจให้ตอบสนองความต้องการของผู้บริโภคและนำมาซึ่งการตัดสินใจซื้อสินค้าและบริการ
อิทธิพลของฟิลเตอร์ประกอบการจัดแสงที่มีผลต่อโทนผิว เพื่อใช้ในการผลิตภาพถ่ายโฆษณาสกินแคร์
Authors: ศักดิ์สิริโกศล ชนิดา 
Published: September 2023

การวิจัยครั้งนี้มีวัตถุประสงค์เพื่อศึกษาอิทธิพลของฟิลเตอร์ประกอบการจัดแสงที่มีผลต่อโทนผิวเพื่อใช้ในการผลิตภาพถ่ายโฆษณาสกินแคร์ ผู้วิจัยใช้ระเบียบวิธีวิจัยการทดลอง ถ่ายภาพนางแบบ 2 สีผิว คือ ผิวสีแทนและผิวสีขาวอมชมพู ซึ่งไม่ใช้ฟิลเตอร์ จำนวน 1 ภาพ และใช้ฟิลเตอร์สีจำนวน 20 สี ถ่ายภาพในสตูดิโอด้วยกล้อง DSLR ยี่ห้อ Canon รุ่น 700D เลนส์ 70-200 mm โดยควบคุมตัวแปร ได้แก่ คุณภาพแสง ตำแหน่งไฟ ขนาดภาพ รูรับแสง 8 เท่ากันทุกภาพ จากนั้นให้กลุ่มตัวอย่าง 30 คน ดูภาพผ่านจอมอนิเตอร์ ประเมินความกระจ่างใส/หมองคล้ำ และผิวนุ่มนวล/หยาบกร้าน ด้วยแบบสอบถาม
ผลการวิจัย พบว่า การผลิตภาพถ่ายโฆษณาสกินแคร์ของนางแบบผิวสีแทนและผิวสีขาวอมชมพูเพื่อแสดงให้เห็นถึงความกระจ่างใสและนุ่มนวล การนำฟิลเตอร์มาใช้ในการจัดแสงไม่มีอิทธิพลต่อการทำให้รู้สึกถึงความกระจ่างใสและนุ่มนวลของนางแบบทั้ง 2 สีผิว ทั้งนี้ อาจเป็นเพราะว่าคุณภาพแสงที่ใช้ในการผลิตภาพถ่ายครั้งนี้เป็นแสงแข็งซึ่งทำให้ภาพสีผิวของนางแบบดูไม่นุ่มนวล แข็งกระด้าง นอกจากนั้น บริเวณผิวหน้ามีเงาสะท้อนมากเกินไป แตกต่างจากภาพถ่ายสกินแคร์ทั่วไปซึ่งนิยมใช้แสงนุ่มในการผลิตภาพถ่าย
Chronic unpredictable mild stress promotes atherosclerosis via adipose tissue dysfunction in ApoE-/- mice
Authors: Mao Min , Deng Yalan , Wang Li , Zhao Gexin , Qi Ruomei , Gong Huan , Shen Tao , Xu Yitian , Liu Deping , Chen Beidong 
Published: September 2023

Background
Chronic unpredictable mild stress (CUMS) has been shown to exacerbate atherosclerosis, but the underlying mechanism remains unknown. Adipose tissue is an energy storage organ and the largest endocrine organ in the human body, playing a key role in the development of cardiovascular disease. In this research, it was hypothesized that CUMS may exacerbate the development of atherosclerosis by inducing the hypertrophy and dysfunction of white adipocytes.

Methods
The CUMS-induced atherosclerosis model was developed in Western diet-fed apolipoprotein E (ApoE)-/- mice. White adipose tissue (WAT), serum, aortic root, and the brachiocephalic trunk were collected and tested after 12 weeks of CUMS development. The mouse model of CUMS was evaluated for depression-like behavior using the open field test (OFT) and the elevated plus maze (EPM) test. Enzyme-linked immunosorbent assay (ELISA) was conducted to detect serum noradrenaline and urine adrenaline protein levels. Serological assays were used to detect serum low-density lipoprotein (LDL), high-density lipoprotein (HDL), total cholesterol (TC), and free fatty acid (FFA) concentrations. Hematoxylin and eosin (H&E) staining and oil red O were used to detect atherosclerotic plaque area, lipid deposition, and adipocyte size. The mRNA levels of genes related to aberrant adipose tissue function were determined using real-time PCR. Immunofluorescence assay and western blotting were conducted to examine the expression of proteins in the adipose tissue samples.

Results
CUMS aggravated vascular atherosclerotic lesions in ApoE-/- mice. It decreased body weight while increasing the percentage of WAT. The serological results indicated that the concentration of HDL decreased in CUMS mice. Notably, adipocyte hypertrophy increased, whereas the mRNA levels of Pparg and its target genes (Slc2a4 (encodes for GLUT4), Adipoq, and Plin1) decreased. Further investigation revealed that CUMS increased subcutaneous inguinal WAT (iWAT) lipid synthesis and adipocyte inflammation while decreasing lipid hydrolysis and the expression of HDL-associated protein ApoA-I. Moreover, CUMS aggravated insulin resistance in mice and inhibited the insulin pathway in iWAT.

Conclusions
These findings indicated that CUMS induces adipose tissue dysfunction via a mechanism that leads to dyslipidemia, increased inflammation, and insulin resistance in the body, thereby exacerbating atherosclerosis. Notably, CUMS that is involved in decreasing the expression of HDL-associated proteins in adipose tissue may be a crucial link between adipose hypertrophy and advanced atherosclerosis. This study reveals a novel mechanism via which CUMS exacerbates atherosclerosis from the novel perspective of abnormal adipose function and identifies a novel potential therapeutic target for this disease.
Assessing the impact of the 2018 tetanus guidelines on knowledge and practices of emergency physicians in trauma patients: a national survey study
Authors: Gao Junling , Yu Xiaxia , Cao Guanghui , He Xiaoming , Zhang Pingde , Walline Joseph , Wang Yuanxi , Yu Xingjuan , Xu Jun , Thach Thuan-Quoc , Liu Yong 
Published: September 2023

Background
Tetanus remains a significant public health issue in China, with the approach of anti-tetanus prophylaxis in the emergency department resulting in both overuse, particularly of human tetanus immune globulin (TIG), and underuse with the tetanus vaccine. This is largely due to the absence of updated guidelines on tetanus prophylaxis before 2018. Our study aimed to evaluate the effects of the 2018 Chinese tetanus guidelines on the knowledge and practices of emergency physicians about tetanus prevention in trauma patients.

Methods
From November 2019 to April 2020, we conducted a web-based survey involving 499 emergency physicians. The survey included a questionnaire covering knowledge, attitudes, and practices related to tetanus. We assessed the influence of the 2018 tetanus guidelines on the knowledge and practices of emergency physicians related to tetanus prevention for patients with trauma using multiple regression analysis.

Results
The survey results showed that only 45.3% of the participants had received formal training on tetanus immunization, despite 53.3% reporting the availability of tetanus vaccines at their institutions. Physicians typically prescribed tetanus antitoxin or human TIG instead of tetanus toxoid (TT) to treat injuries, regardless of the patient’s TT vaccination history. Among the respondents, those who were aware of the 2018 tetanus guidelines had higher mean scores on the general knowledge, risk knowledge, and treatment knowledge scales, with increases of 6%, 13%, and 9%, respectively, compared to those who were unaware of the guidelines. Awareness of the 2018 tetanus guidelines was associated with a high level of knowledge, as indicated by the general knowledge score, recommendation knowledge score, and total knowledge score, after adjusting for the effects of all variables on the knowledge, attitudes, and practices of the participants. A high level of education was also associated with a high level of knowledge indicated by the recommendation knowledge score and total knowledge score.

Conclusions
Our study highlights a substantial gap in the attitudes, knowledge, and practices of emergency physicians in China regarding tetanus immunization. The results suggest an urgent need to promote the Chinese Expert Consensus Guidelines on tetanus to improve emergency physicians’ knowledge and competence in tetanus prophylaxis. The findings underscore the importance of enhancing physicians’ awareness of the latest guidelines to ensure appropriate and effective treatment for patients with tetanus-prone injuries.
Assessment of the Barrier Performance of the Flourosilicone Treated Fabric Exposed to Pesticides Spraying to Chilli Crop at Laboratory Conditions
Authors: Prabhavathi R. , Anitha D. , Vastrad Jyothi , Neeraja T. , Prakash K. Kiran 
Published: September 2023

In this study, in view of development of protective clothing for pesticide sprayers in chilli crop, the suitable fabric polyester 67/cotton 37 with weight 157.7 GSM was selected. BOND-WR-12-A RTU was aqueous fluorosilicone durable water and oil repellent emulsion was used to treat the fabric by using different application parameters at the rate of 5 per cent concentration. As per Chowdhury, 2018 water repellent finish type and concentrations were very important parameters to obtain water repellent fabric having acceptable use properties. Later, the treated fabric was exposed to the selected pesticides like Phosphamidon, Monocrotophos and Dimethoate for for three exposures. By estimating the absorption and penetration behaviour of the treated and untreated fabrics, the performance of silicon finish was determined by using four factor with CRD and Heuristic method. From this result, the treated fabric had restricted the absorbency over control fabric and the Studies on barrier clothing, [1,2] suggested that blends of polyester cotton and polyester viscose showed better barrier performance with minimum penetration of pesticides than other blended fabrics. Hence it can be used in development of protective clothing for pesticide applicators in chilli crop or any other field crops where ever pesticides are used.
The Liver Function Score – “ALBI” Sets Apart Melioidosis, Scrub Typhus from Viral Hepatitis, Tuberculosis, Enteric Fever in a III-II Grade Score: Useful in Machine Learning and AI
Authors: Kannan Sriram , Pandey Apoorva , Singh Suchita , Chowdhury Soumi , Earny Venkat Abhiram , Ashiq Mohammed , K. E. Vandana , Mukhopadhyay Chiranjay , Kaur Harpreet 
Published: September 2023

ALBI (Albumin-Bilirubin) score is routinely used in grading liver function of hepatocarcinoma and hepatitis patients. In this purposive review, the published values of serum albumin, bilirubin in Viral hepatitis, Tuberculosis, Scrub typhus, Enteric fever has been compared with that of melioidosis. Since PubMed yielded zero searches with key words “albumin, bilirubin, melioidosis”, it was searched in Google Scholar, a better retrievable search engine. This yielded 46 relevant articles with 53 ALBI scores for Melioidosis. An equivalent search to retrieve 53 ALBI scores was made in Google Scholar for other confounding diseases of Melioidosis with search words “albumin, bilirubin, hepatitis” “albumin, bilirubin, tuberculosis”, “albumin, bilirubin, scrub typhus”, “albumin, bilirubin, enteric fever”. This raw data was deposited in Harvard dataverse (https://doi.org/10.7910/DVN/QEW20J) and subsequent analysis done is documented in this article. This placed Melioidosis patients and Scrub typhus patients to be on an average grade III ALBI and the patients of Viral hepatitis, Tuberculosis, and Enteric fever in grade II ALBI.
GRAPHICAL ABSTRACT
Quality Assessment of Sokoto Water Distribution Networks
Authors: Bello M. T. , Bichi M. H. 
Published: September 2023

The research is on the quality assessment of Sokoto water distribution networks. Sample coordinates of the study area were taken using GPS, the experiments were carried out at different consumer locations with thirty (30) samples of water collected weekly for four (4) weeks, to determine various purification parameters that are related to both bulk (kb) and wall (KW) reactions coefficients for Sokoto water distribution pipe network, these include residual chlorine, pH, dissolved oxygen (DO), temperature and conductivity. pH, dissolved oxygen (DO) and conductivity have average values ranging from 6.7 to 7.5; 1.1 to 6.5ppm; 310 to 520 μs/cm respectively and conform to the Nigerian Standard for Drinking Water Quality (NSDWQ), except temperature which has the average values between 29 oC, and 32.6oC, and the individual values between 26 oC, and 38.4oC, chlorine residual average values obtained, ranging from 0.11mg/l to 0.26mg/l with the lowest individual value obtained being 0.011mg/l. The age of water supply from the treatment plants in the distribution network is 6 hours and both first and second-order decay reactions were ascertained from the graph and first-order decay having the highest number of occurrences was used in Epanet 2.0 water quality modeling. The kb values ranged from 0.0025 to 0.013md-1. A total of 86 out of the 120 samples, which constitute 71.7% were straight lines which indicate first-order and thus, the average kb was determined to be 0.006/day (0.144/hour). It was observed that of all the 120 samples examined in the study, chlorine reaction with natural organic matter (NOM) was small. The average kw for Sokoto WDS was deduced to be 0.078m/h, considering, the following steel pipe conditions used in the network area. kW (ft/h), -α =-38.5, H-W C=150, kW = 38.5/150 = 0.257ft/h = 0.078m/h (-0.078m/h).
Mental health outcomes of physical, sexual, and psychological intimate partner violence among women in Turkey: A latent class study
Authors: Yastıbaş‐Kaçar Cennet , Uysal Mete S. , Güngör Duygu 
Published: September 2023

AbstractIntimate partner violence (IPV) is a severe human right violation and a significant public health problem in Turkey. However, its complexity and stratified relationship with mental health problems are still uncovered in this under researched community, as violence is often approached as a uniform health and social problem. In this study, we collected data from 539 female adults in heterosexual relationships in Turkey using convenience and snowball sampling. The aim was to examine violence‐related clusters and their association of these clusters with mental health outcomes, including depression, anxiety, and depression). We assessed whether participants experienced physical, sexual, and psychological violence in their intimate relationships and conducted a latent class analysis. We obtained five violence clusters: (1) no or low violence, (2) high psychological violence, (3) jealous control with physical violence, (4) moderate sexual and psychological violence, and (5) severe physical, sexual, and psychological violence. Analyses of variance showed that women who experienced multiple forms of IPV reported stronger depression, anxiety, and somatization compared with women in the no or low violence class. Additionally, they reported greater depression and anxiety compared with women who experienced only high psychological IPV. However, psychological violence amplified somatization as much as physical and sexual violence.