bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Practical Inverse Design Approach for High-Entropy Catalysts with Generative AI
Authors: Jiang Jun , Zhou Donglai , Yang Ruyu , Jia Zijin , Cai Yuhai , Zhao Luyuan , Guo Lulu , Ye Guilin , Wang Song , Chen Linjiang , Liu Daobin , Smith Pieter E. S. , Huang Yan , Zhu Qing 
Published: January 2025

Abstract

The vast compositional space of high-entropy materials offers unprecedented opportunities for the development of powerful catalysts. However, their inverse design remains unfeasible due to the lack of robust theoretical frameworks and high-throughput experimental tools. This study demonstrates a practical inverse design approach that integrates spectroscopic descriptors, generative machine learning, and a robotic experimental platform to synthesize and optimize catalyst composition for the oxygen evolution reaction (OER). The automated system significantly accelerated catalysts design and experimental validation, reducing the time required for synthesis, characterization and performance testing from approximately 20 hours to only 78 minutes per sample. Following a rapid screen for efficient senary high-entropy catalysts, the spectroscopic generative model further optimized the top-performing candidate, lowering its overpotential at 10 mA/cm2 by an additional 32 mV. Our findings are a testament to the potential of an inverse design approach that incorporates spectroscopic descriptors into generative machine learning to accelerate catalyst discovery. Moreover, this approach is also expected to drive the intelligent design of high-performance complex materials.
Recurrent SCAD Complicating Left Circumflex Stenting
Authors: Ndakotsu Andrew , Iqbal Shaikh B. , Mamoh Ufuoma , Wang John C. , Padmanabhan Sriram , Kaliyadan Anthony G. 
Published: January 2025

Abstract

Spontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndrome often requiring either conservative management or intervention. This case describes a 49-year-old woman with recurrent SCAD who developed a spiral dissection of the left circumflex artery during PCI, necessitating multiple stents. It highlights the challenges of SCAD, including dissection propagation. The report emphasizes procedural caution and tailored care to improve outcomes in high-risk SCAD patients.
A group-based narrative intervention on self-stigma, self-esteem, and psychological capital for hospitalized patients with schizophrenia：a case-series study from mainland China
Authors: Zhou Qian , Wei Yuhua , Huang Zaifei , Zhao Yue , Qin Sujiao , Wei Xuewei , Wei Lianou , Huang Da , Qin Mingkang , Zeng Lingjun , Qin Fengqiong , Huo Yuting 
Published: January 2025

Abstract

Self-stigma has been consistently cited as a major obstacle to recovery-related outcomes among patients with schizophrenia. To examine the feasibility, acceptability, and preliminary efficacy of the group-based narrative intervention for improving self-stigma, self-esteem and psychological capital in hospitalized patients with schizophrenia, a case-series study was conducted from March to May 2023 in a closed psychiatric ward of a specialized hospital in mainland China. Feasibility was assessed by examining rates of recruitment, retention, and protocol adherence. Acceptability was assessed through the therapist’s and patients’ feedback about the intervention. Changes in the levels of self-stigma, self-esteem, and psychological capital perceived by patients were measured before and after four weeks of intervention. Rates of enrolment (85%) and completion of intervention sessions and study procedures (100%) were excellent, demonstrating high rates of feasibility among these patients in the local setting. The feedback from participants and the therapist about satisfaction, helpfulness, and difficulty of the intervention was largely positive, demonstrating high rates of acceptability. And the results indicated significant improvements in patients’ self-reported self-stigma, self-esteem, and psychological capital (change in T = 3.872, P = 0.001; T = -6.308, P < 0.001; T = -2.895, P = 0.011, respectively). The study provided a structured intervention program for clinical care to reduce self-stigma and promote positive recovery outcomes for inpatients with schizophrenia.
Association of glycation gap with hypoglycemia CGM indices in Japanese patients with type 2 diabetes mellitus
Authors: Sonoda Satomi , Okada Yosuke , Mita Tomoya , Torimoto Keiichi , Tanaka Kenichi , Sato Fumiya , Katakami Naoto , Yoshii Hidenori , Nishida Keiko , Tanaka Yoshiya , Ishii Ryota , Gosho Masahiko , Shimomura Iichiro , Watada Hirotaka 
Published: January 2025

Abstract

The glycation gap (GGap), defined as the discrepancy between glycated hemoglobin (HbA1c) and the value estimated from actual blood glucose level, is associated with diabetic complications, but its association with hypoglycemia remains unclear. We evaluated the association between GGap and continuous glucose monitoring (CGM)-based hypoglycemic indices in patients with type 2 diabetes mellitus (T2DM). Baseline data from a multicenter cohort of 999 T2DM patients without cardiovascular disease were analyzed. The difference between HbA1c and estimated A1c (eA1c) was defined as the GGap, and various CGM indices were compared among low (≤0.16), medium (<0.16 to ≤0.60), and high (>0.60) GGap tertile groups. In the high GGap group, the average blood glucose was lower, while the Time Below Range <3.9 mmol/L (TBR<3.9) and <3.0 mmol/L (TBR<3.0), and low blood glucose index (LBGI) were higher than the low and middle GGap groups. Patients with minimum blood glucose levels of <3.9, <3.0 mmol/L, and TBR<3.9≥4%, and TBR<3.0≥1% had significantly higher GGap values. This is the first study to show the strong association of high GGap with CGM-based hypoglycemic indices with T2DM. To achieve diabetes treatment that effectively prevents the progression of diabetic complications, it is essential to assess the GGap of the individual patient before intensifying diabetes management.
Investigating the nutritional composition of cultured Asian seabass Lates calcarifer in Bangladesh's Khulna-Satkhira region: A focus on fatty acids and amino acids
Authors: Sikder Roni , Haque Wahida , Das Saikat , Shaon Md. Akeruzzaman , Islam Md. Zafrul , Hasan Md. Rakibul 
Published: January 2025

Abstract

Lates calcarifer, known as Asian seabass, is a brackish-water teleost species within the order Carangiformes, native to the Indo-Pacific region. In Bangladesh, this species is found in natural habitats and cultivated on a small scale in the southern coastal region, particularly in the Khulna-Satkhira area. This study analyzed the nutritional composition of cultured Asian seabass in two different size categories, 512.06 ± 14.5 g and 1003.5 ± 36.64 g, collected from this region. Our findings revealed significant differences in the proximate compositions of the two size groups, except ash content (independent t-test, p < 0.05). The smaller size group had a notably higher moisture content (74.96 ± 0.04%), whereas the larger fish exhibited significantly greater protein and fat contents (20.48 ± 0.1% and 5.34 ± 0.18%, respectively). Fatty acid analysis showed distinct differences as well; the larger size group contained higher concentrations of saturated fatty acids (SFAs) and monounsaturated fatty acids (MUFAs), while the smaller fish was richer in polyunsaturated fatty acids (PUFAs). Among the SFAs and omega-3 PUFAs, undecanoic acid and α-linolenic acid were the most prevalent in both groups. However, MUFA profiles differed: palmitoleic acid was dominant in the smaller size group, while oleic acid was more abundant in the larger size group. All essential amino acids (EAAs), except tryptophan, were detected in both groups, with lysine being the most prominent, measuring 5.53±0.44 g/100 g dry weight in smaller size group and 3.91±0.32 g/100 g dry weight in larger size group. Notably, the smaller size group demonstrated a significantly higher overall concentration of EAAs. Overall, this study highlights the nutritional richness of cultured Asian seabass, particularly in terms of fatty acid and amino acid profiles. The superior concentrations of essential amino acids, a higher EPA/DHA ratio, and a more favorable n-3/n-6 ratio in the smaller fish suggest it as a nutritionally superior and well-balanced fish option.
An association between inferior posterior staphyloma on choroidal vessels running patterns in healthy eyes
Authors: Terasaki Hiroto , Funatsu Ryoh , Okamura Koki , Mihara Naohisa , Shiihara Hideki , Yamashita Takehiro , Sonoda Shozo , Sakamoto Taiji 
Published: January 2025

Abstract

Background
The effects of ocular shape changes on the retina have been studied in pathologic myopia. However, it is not well known whether there are individual differences in ocular shape in non-pathologic myopia and the influence of ocular shape on retinochoroidal disease in these eyes. Ultra-wide-field OCT (UWF-OCT), which has recently become available, has a wider imaging range and can be used to evaluate inferior posterior staphyloma (IPS). We aimed to investigate the effect of IPS on Haller vessel running patterns (HVRPs) in healthy eyes using UWF-OCT.
Methods
This single-center retrospective study included healthy subjects. UWF-OCT images of normal subjects were stretched vertically to enhance the macula's shape and classified into IPS and non-IPS groups with or without propensity score matching for age, sex, and ocular axis length. The HVRPs were subjectively classified into symmetry, superior dominant, and inferior dominant. Differences in the proportions of the patterns in the two groups were compared using Fisher's exact test.
Results
In the non-IPS group, 65 (57.5%) individuals had a symmetric pattern of Haller's vessels, 32 (28.3%) had an upper-dominant pattern, and 16 (14.1%) had a lower-dominant pattern. In the IPS group, 14 eyes (87.5%) presented an upper dominant pattern, and two (12.5%) presented a symmetric pattern. The two groups had a statistically significant difference in vascular running patterns (P < 0.001). After PSM, a similar trend was confirmed.
Conclusions
The eyes with IPS are likely to have superior dominant HVRPs compared to the non-IPS group in healthy eyes. Macular shape may play a role in HVRPs, which are involved in the pathogenesis of retinochoroidal diseases.
Neural Computing in Medical Image Analysis for Cancer Detection
Authors: Rather Khalid Ul Islam 
Published: January 2025

Abstract

Early and accurate detection of cancerous tissues is critical for improving patient outcomes and optimizing treatment strategies. This study explores the application of convolutional neural networks (CNNs) in the analysis of medical images, such as MRI and CT scans, for cancer detection and classification. Leveraging advanced neural computing techniques, the proposed system aims to enhance diagnostic accuracy while minimizing false positives and false negatives. The research involves the development and validation of a CNN-based framework trained on a diverse dataset of annotated medical images. The model's performance is evaluated against conventional diagnostic methods and state-of-the-art deep learning approaches. Results indicate significant improvements in classification accuracy, robustness to variations in image quality, and computational efficiency. This study underscores the potential of neural computing to revolutionize cancer diagnostics and support clinicians in making informed decisions.
Predicting prognosis of sepsis in patients based on right ventricular strain imaging : development and validation of a nomogram model
Authors: Wang Qinxin , Chen Hongmin , Zhou Chang , Xing Boyuan , Liu Yun , Li Chang 
Published: January 2025

Abstract

Background
Sepsis-related right ventricular systolic dysfunction (RVSD) causes myocardial injury and organ failure. Recognition of risk indicators and predictive models for sepsis outcomes can improve right ventricular dysfunction identification. However, research on risk indicators and predictive models for sepsis-related right ventricular failure is sparse.
Objective
To identify sepsis risk indicators and develop a right ventricular strain imaging-based predictive model.
Methods
A single-center prospective study included 156 sepsis patients admitted from September 2021 to October 2024. General clinical, laboratory, and echocardiographic data were collected within 72 hours of sepsis diagnosis. Prognosis divided patients into two groups. Multivariable logistic regression analysis and a nomogram were used to predict sepsis prognosis. The relationship between RVSD and 28-day mortality was also examined.
Results
52 of 141 sepsis patients died within 28 days. Univariate analysis showed that the non-survivor cohort was older, had higher APACHE II and SOFA ratings, PCT, BNP, cTnI, and lactate. RV-free wall strain (-18.9% ± 1.6% vs. -20.1% ± 1.5%, P < 0.001) and RV global strain (-18.6% ± 1.4% vs. -17.6% ± 1.0%, P < 0.001) were lower in the non-survivor group compared to the survivor cohort. Significant differences in PASP and RV-GS/PASP ratio were observed between the two groups (P < 0.05). Multivariable logistic regression analysis identified age > 67, SOFA score ≥ 7.5, PCT ≥ 5.7 ng/ml, Lac ≥ 3.5 mmol/L, RV-FWS ≥ -19.4%, and RV-GS/PASP ≥ -0.55 as independent risk factors for poor sepsis outcomes. The prognostic model using these six risk factors has an AUC of 0.907.
Conclusion
Sepsis outcomes were worse in people 67 years or older with a SOFA score of 7.5 or higher, PCT levels of 5.7 ng/ml or higher, lactate levels of 3.5 mmol/L or higher, RV-FWS of -19.4% or lower, and RV-GS/PASP of -0.55 or lower. Prognostic studies showed that sepsis patients with right ventricular failure had higher death and AKI rates.
Influence of Cajuput Leaf Residue on the Properties of Lightweight Expanded Clay Aggregate
Authors: Werapun Uraiwan 
Published: January 2025

Abstract

This study investigates the utilization of cajuput leaf residue as an additive in the production of Lightweight Expanded Clay Aggregates (LECA). The solid cajuput residue, a by-product of cajuput oil extraction, was mixed with clay in varying ratios (0%, 10%, 20%, 30%, and 40% by weight, denoted as 0%RW, 10%RW, 20%RW, 30%RW and 40%RW, respectively) to form pellets, which were then sintered at 800°C. Besides, the study of temperature effects was conducted on samples containing 40% cajuput leaf residue, sintered at 700 °C, 800 °C, and 900°C. The physical properties bulk density, water absorption, and porosity were assessed, alongside microstructural and chemical analyses using SEM and EDS techniques. The results showed that increasing the cajuput leaf residue content significantly enhanced porosity and water absorption while reducing bulk density, with optimal performance observed at 800°C. The findings demonstrate the potential of cajuput leaf residue in developing eco-friendly LECA for applications such as plant growth media, with this waste recycling contributing to circular economy initiatives.
¿De dónde vienen los microplásticos?
Authors: Flores-Ocampo Itzamna Zaknite , Ibarra-Rueda Sandra Elizabeth , Morales-Arredondo José Iván 
Published: January 2025

El siguiente texto es una lectura para introducir a niños y adolescentes en el tema de contaminación por microplásticos dado que es un tipo de contaminante que, desafortunadamente, está presente en todos lados, aunque no lo veamos a simple vista. En el contenido de este trabajo se menciona cuáles son los productos más comunes de plástico que utilizamos, de dónde vienen, cómo se forman y dónde terminan los microplásticos y cuál es la importancia de estudiarlos. Este tema cada vez toma mayor interés entre la población y es importante que se difunda entre la población más joven. El objetivo es que los niños y jóvenes, al finalizar la lectura puedan reflexionar y contestar preguntas importantes como ¿Sabías que estas consumiendo microplásticos sin darte cuenta? ¿Conoces qué daños ocasionan los microplásticos al medio ambiente? ¿Qué productos son los mayores aportadores de plástico al ambiente?
Fiesta y poder en Nueva España: la reforma festiva de 1789
Authors: Enríquez Sánchez Antonio de Jesús 
Published: January 2025

El presente artículo analiza la función política que desempeñó la fiesta durante el siglo XVIII a partir de la reforma festiva realizada por Carlos IV al calendario de la Real Audiencia de Nueva España. Se revisan las razones por las cuales disminuyó el número de festividades a las que asistía el tribunal, así como el curso de esta iniciativa. Uno de los aspectos que se exploran es la función que tuvo la fiesta como promotora de la Corona, asunto que se vislumbra en la reforma de 1789 y se constata en los años siguientes con las festividades vinculadas con el monarca, y en las cuales tomó parte la Real Audiencia.
Evaluasi Sistem Informasi Manajemen Pelayanan Kepegawaian Elektronik (SIMPEL) di BKPSDM Kabupaten Serang
Authors: Mulyani Ade , Budiati Ayuning , Maulana Delly 
Published: January 2025

E-government has become a necessity for every agency to speed up access and services. The SIMPEL application at BKPSDM Serang Regency aims to create an effective and efficient paperless personnel service system. This research was to evaluate the SIMPEL application. This research implements the information systems model developed by Yusof,et al. This research was used to test whether the system quality, information quality, and quality service influence system use and user satisfaction, and test whether system use, user satisfaction and organizational structure have an effect on net benefit. This research used quantitative methodology with a sample of 58 respondents from SIMPEL users. Data was taken by respondents who filled out questionnaires and measured with a Likert scale. The data analysis method used is the Multiple Linear Regression Test using SPSS Version 26 software. Test indicates that system quality, information quality and service quality has influence on system usage and user satisfaction, while user satisfaction, system use and organizational structure has influence on the net benefit (level of significant α = 0.05).
RME model based on ethnomathematics “prol tape” typical of Jember in improving fraction concept understanding of madrasah ibtidaiyah students
Authors: Sufraini Sufraini , Dewanti Sintha Sih , Anriani Titi , Budi Tegar Setia , Isnaini Safira Wahyu 
Published: January 2025

Background: This research stems from the problem of learning mathematics, which is still considered scary and difficult. Less varied learning methods make this learning boring for students. Through the development of this Realistic Mathematics Education (RME) learning model based on Jember's typical prol tape ethnomathematics, students enjoy learning more.Aim: This research aims to develop an RME learning model based on ethnomathematics "prol tape" typical of Jember City in improving the understanding of the concept of fractions of Madrasah Ibtidaiyah (MI) students.Method: This research is a kind of R&D (Research and Development) development research, using the 4-D development model (four D models) developed by Thiagarajan. This research was conducted at MI Ar-Roudhoh in the even semester of the academic year 2023/2024, with the research subjects being grade 2 teachers and grade 2 students. Data collection techniques through interviews, observations, and documentation.Result: The results showed that the percentage of students' learning completeness, namely 86.36%, met the criteria so that the developed products were effective for use. The obtained average N-gain value of 0.77 is in the high category, indicating that the application of the ethnomathematics based RME learning model can improve students' concept understanding ability on fraction material. Students' responses also showed a positive response, besides knowing the story, this media can make it easier for them to learn fraction material.Conclusion: This research can provide insight into how an RME learning model can be developed by integrating mathematics with local culture. The conclusions drawn here contribute to a broader understanding of the RME learning model in mathematics learning, providing a new perspective by innovating learning strategies used in educational practice.
Exploring the relationship between problem-solving ability and mathematical disposition in 10-11 year’s old students using model-eliciting activities
Authors: Wahyuningrum Endang , Bonyah Ebenezer , Yumiati Yumiati , Kartono Kartono , Wijayanti Nina 
Published: January 2025

Background: Problem-solving ability and mathematical disposition are essential skills in mathematics education, particularly in developing critical thinking and practical application among students. Model-Eliciting Activities (MEAs) have been introduced as an instructional approach aimed at enhancing these skills by integrating real-world problems into learning. However, the effectiveness of MEAs in establishing a significant relationship between problem-solving ability and mathematical disposition remains unclear, necessitating further investigation.Aim: This study aims to analyze the association between problem-solving ability and mathematical disposition after implementing Model-Eliciting Activities (MEAs) in instruction.Method: This study employed a quantitative design with a cross-sectional approach, involving 30 fifth-grade students from SDN 02 Bojongsari, Depok, Indonesia, as participants. Data were collected using a problem-solving ability test and a mathematical disposition questionnaire. Subsequently, the data analysis was carried out using chi-square tests.Result: The results of the study showed that the χ2 value of 0.731 is less than α = 0.947, indicating that there is no significant relationship between mathematical problem-solving ability and mathematical disposition.Conclusion: The study concluded that no association was found between problem-solving ability and mathematical disposition among elementary school students after implementing MEAs in instruction. Additionally, although there is a tendency for students with a high mathematical disposition to demonstrate stronger problem-solving skills, this correlation is not strong enough to be considered significant
Fly Ash Polymer Composites Enhancing Pore Refinement and Sulphate Resistance in Cement
Authors: Gangele Chandan , Rai Anubhav , Dubey Satyendra 
Published: January 2025

Fly ash has also become quite renowned as an important by-product material from the combustion of coal it finds various applications as an additive to both polymer composites and cementitious systems, primarily enhancing their mechanical properties including compressive strength, wear resistance, and resistance against sulphate penetration as well as reduced porosity resulting from pozzolanic reactions. This review focuses on the synthesis, characterization, and diversified applications of fly ash polymer composites, which include pore refinement and long-term stability. Advanced analytical techniques, such as scanning electron microscopy (SEM), X-ray diffraction (XRD), and thermogravimetric analysis (TGA), are essential in understanding the microstructure and hydration mechanisms of these composites.