bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dissecting the Mid-infrared Heart of M83 with JWST
Authors: Hernandez Svea , Jones Logan , Smith Linda J. , Togi Aditya , Aloisi Alessandra , Blair William P. , Hirschauer Alec S. , Hunt Leslie K. , James Bethan L. , Kumari Nimisha , Lebouteiller Vianney , Mingozzi Matilde , Ramambason Lise 
Published: May 2023

Abstract
We present a first look at the MRS observations of the nucleus of the nearby galaxy M83, taken with MIRI on board JWST. The observations show a rich set of emission features from the ionized gas, warm molecular gas, and dust. To begin dissecting the complex processes in this part of the galaxy, we divide the observations into four different regions. We find that the strength of the emission features varies strongly from region to region, with the southeast region displaying the weakest features tracing the dust continuum and interstellar medium (ISM) properties. Comparison between the cold molecular gas traced by the 12CO (1–0) transition with the Atacama Large Millimeter/submillimeter Array and the H2 S(1) transition shows a similar spatial distribution. This is in contrast to the distribution of the much warmer H2 emission from the S(7) transition found to be concentrated around the optical nucleus. We use the rotational emission lines and model the H2 excitation to estimate a total molecular gas mass accounting for the warm H2 component of M(>50 K)

H

2

= 67.90 (±5.43) × 106
M
⊙. We compare this value to the total gas mass inferred by probing the cold H2 gas through the 12CO (1–0) emission, M(CO)

H

2

= 17.15 × 106
M
⊙. We estimate that ∼75% of the total molecular gas mass is contained in the warm H2 component. We also identify [O iv] 25.89 μm and [Fe ii] 25.99 μm emission. We propose that the diffuse [Fe ii] 25.99 μm emission might be tracing shocks created during the interactions between the hot wind produced by the starburst and the much cooler ISM above the galactic plane. More detailed studies are needed to confirm such a scenario.
Helminth Infection among Children Living in an Urban Area in Tropical Countries: A Systematic Review
Authors: Soffian Sharifah Saffinas Syed , Baharom Mazni , Amir Siti Maisara , Bahari Nor Izyani , Hassan Mohd Rohaizat , Rahim Syed Sharizman Syed Abdul , Jeffree Mohammad Saffree , Ramdzan Abdul Rahman , Atil Azman , Mokti Khalid , Madrim Mohd Faizal , Rahim Muhammad Aklil Abd , Ahmad Zulkhairul Naim Bin Sidek 
Published: May 2023

Background

Neglected tropical diseases (NTDs) are a group of preventable and treatable diseases, in which soil-transmitted helminth (STH) infections are among the most common infections worldwide. Most affected are the children and this review aims to identify the prevalence, risk factors and impact of STH in an urban area.

Methodology

This review was guiding using PRISMA review protocol incorporating the research question of “What is the prevalence, risk factors and impact of helminth infection among urban children in tropical countries?". The databases used in this review include SCOPUS, WEB OF SCIENCE, OVID MEDLINE and PUBMED. The articles used include observational and interventional studies conducted among children aged 18 years and less from 2010 to 2020. The main outcome measure was risk factors of STH infection seen in urban children includes social backgrounds, sanitation and policy.

Results

From the initial 973 articles found in the database searching, only 13 articles selected for qualitative synthesis after exclusion and screening for eligibility done. The overall prevalence of helminth infection among urban children ranges from 4.8-48.9%. The associated factor that influences helminth infection among children living in an urban area are age, male more common than female, low socioeconomic status, low parents’ education level, living in an urban slum or crowded area, low water quality and sanitation practice and poor hygiene practice. The deworming tablets consumption acts as protective factors for helminth infections. The medium haemoglobin value was significantly lower in helminth-infected children compared to uninfected children and the stunting, underweight as well as moderate acute malnutrition were attributable to helminth infections.

Conclusion

The prevalence and intensity of helminthiasis were heterogeneous among urban areas of developing countries, however, the endemicity is still high. Further efforts including healthy policies, continuous national deworming programmes and multi-sectoral partnership are required to reduce the prevalence of helminthiasis in the urban area.
La fidélisation des jeunes à faible capital scolaire initial dans les TPE/PME de l’hôtellerie-restauration : une mission impossible ?
Authors: Fournier Sandrine , Chakor Tarik 
Published: May 2023

Secteur d’activité en tension, caractérisé par un nombre pléthorique d’offres d’emplois et une pénurie de main-d’œuvre, l’hôtellerie-restauration fait face à des enjeux RH majeurs. Marqué par un management directif, un rythme de travail intense, empreint d’une culture professionnelle transmise par mimétisme depuis des générations et d’une éthique métier stricte, la fidélisation des salariés, notamment des plus jeunes, constitue un enjeu de premier plan. Cette recherche a pour objectif d’analyser la question de la fidélisation des jeunes à faible capital scolaire initial (JFCSI) au sein des TPE/PME. Pour répondre à cet objectif, nous mobiliserons un cadre théorique articulant théorie des échanges sociaux et attentes individuelles. Nous présenterons notre démarche exploratoire interprétativiste et qualitative, réalisée à partir d’entretiens semi-directifs menés auprès de 37 jeunes en début de parcours professionnel et de 10 responsables, et d’observations participantes. Nos résultats mettront en lumière une fidélisation dans l’impasse, entre non-réciprocité perçue des échanges sociaux et attentes paradoxales des JFCSI et des encadrants. Ces résultats seront enfin mis en discussion, autour de la nécessité de repenser l’intégration et la socialisation organisationnelle des nouveaux entrants au prisme des spécificités du secteur.
La résilience organisationnelle face à la crise de la Covid-19 : le cas de deux entreprises dans le secteur du tourisme
Authors: Altintas Gulsun 
Published: May 2023

Dans la littérature sur le tourisme, les travaux ont principalement porté sur la résilience des systèmes touristiques. Les études sur la résilience des entreprises sont plus rares d’une part, et, d’autre part, elles énoncent des facteurs de résilience sans préciser si ceux-ci sont communs aux entreprises ou s’ils peuvent être différents en fonction des caractéristiques organisationnelles. Notre étude qui porte sur la gestion de la crise liée à la Covid-19 par deux tour-opérateurs permet de comprendre que le processus de résilience est identique pour les deux entreprises. Il est composé de quatre phases : l’impact de la crise, les réponses pour réduire l’impact de la crise, les réponses pour relancer les activités et l’apprentissage. En revanche, certains facteurs de résilience s’avèrent différents. Les différences s’expliquent par quatre caractéristiques organisationnelles : la spécificité de l’offre, la taille de l’entreprise, la gouvernance d’entreprise et les valeurs managériales.
Primera cita del caracol exótico Helisoma duryi (Wetherby, 1879), (Gastropoda: Planorbidae) en Marruecos
Authors: Fouzi Taybi Abdelkhaleq , Glöer Peter , Mabrouki‍ Youness 
Published: May 2023

El molusco exótico Helisoma duryi es un popular caracol ornamental de agua dulce que se utiliza para controlar las microalgas en los acuarios. Ahora se presenta como una especie introducida en hábitats acuáticos de Europa, África y América del Sur. Presentamos el primer hallazgo de una población aclimatada de H. duryi en Marruecos y el norte de África. A pesar de ubicarse en una única localidad de las más de 100 muestreadas por nosotros, las investigaciones en curso podrían revelar pronto más citas de la especie en el país y el resto del continente. Se deben establecer políticas y procedimientos estrictos de aplicación de la ley en el comercio de especies acuáticas como medida preventiva para preservar la biodiversidad nativa.
Carcass characteristics and meat quality of lambs fed diets with different roughage: concentrate ratios supplemented with liquid residue of cassava
Authors: Guim Adriana , Silva Karla Katiene de Souza , Véras Robson Magno Liberal , Leite Paulo Márcio Barbosa de Arruda , Abreu Karen Santos Félix de , Cardoso Daniel Barros 
Published: May 2023

The objective of this study was to evaluate the effects of lambs fed two roughage: concentrate (R:C) ratios, with or without the liquid residue of cassava (LRC) on carcass traits and meat quantity. Forty lambs (19.5 ± 1.45 kg body weight), non-castrated, crossbred Santa Inês were distributed in a completely randomized 2 × 2 factorial design. There was no effect (p > 0.05) of the inclusion of LRC on the variables. The roughage:concentrate ratio of 40:60 promoted higher values for empty body weight, hot carcass weight, cold carcass weight, subcutaneous thickness fat, cooling loss, Longissimus muscle area, carcass morphometric measurements, and commercial cuts. Higher weight of leg, muscles, fat, bone and other tissues, as well as for the ratio muscle:fat, and muscle:bone was observed in lambs fed 40R:60C. For the meat chemical composition, there was the effect (p < 0.05) only for ether extract (EE) for lambs fed 40R:60C ratio. The redness (a*) of meat was greater (p < 0.05) for lambs fed 80R:20C. The other physicochemical characteristics were not influenced. The roughage:concentrate ratio of 40:60 improves the carcass traits and commercial cuts, but does not promote changes in meat quality, independent of supplementation with liquid residue of cassava.
Formulation of a gambier catechin-loaded nanophytosome and the MTT assay on HeLa cell lines
Authors: Lucida Henny , Hasani Suci , Susanti Meri , Ismed Friardi 
Published: May 2023

Background: Catechins are good free radical scavengers but exhibit low stability and permeability. Nanophytosomes are currently being developed as the delivery system for phytoconstituents to protect them from decomposition by oxidants or enzymes and increase their permeability.
Objectives: To formulate gambier catechin-loaded nanophytosomes and perform the MTT assay on HeLa cell lines.
Method:Five formulations were prepared using soya lecithin at various molar ratios of cholesterol by thin-layer hydration and sonication. The nanophytosomes were characterised by the determination of vesicle size, zeta potential, polydispersity index, morphology with Transmission Electron Microscope, Fourier Transform Infrared Spectroscopy (FT-IR) analysis, freeze and thaw test, entrapment efficiency, and the in vitro cytotoxicity test.
Result: The optimal formula (F4) with a molar ratio of 1:1:0.8 (catechin:lecithin:cholesterol) resulted in spherical vesicles with an average size (106 ± 0.218) nm, zeta potential -68 mV, polydispersity index 0.412, 93.5% entrapment efficiency and that were stable to temperature changes. FT-IR showed the formation of catechins and lecithin complexes. The activity of catechin-loaded nanophytosomes against HeLa cells showed an IC50 of 36.307 g/ml. There was a significant difference in the average percentage of cells undergoing apoptosis in all treatment groups (p < 0.05).
Conclusion: Catechin-loaded nanophytosomes with a molar ratio of 1:1:0.8 (catechin:lecithin:cholesterol) showed moderate cytotoxic activity against HeLa cell lines.
Curcumin-mediated gene expression changes in Drosophila melanogaster
Authors: Asfa Nurfadhilah , Widianto Ahmad Shayful , Pratama Muhammad Khadafi Anugrah , Rosa Reski Amalia , Mu’arif Ahmad , Yulianty Risfah , Nainu Firzan 
Published: May 2023

Background: Curcumin has been suggested to be useful in the treatment of numerous diseases, including autoinflammation, that has been implicated in some pathological conditions. Experimentally, autoinflammatory phenotypes were observed in the short-lived Peptidoglycan recognition protein LB (PGRP-LB) mutant of Drosophila melanogaster.
Objective: This study aimed to determine the effect of curcumin on the expression of ageing-related genes in the autoinflammatory model of D. melanogaster.
Method: This study was performed using five test groups including untreated control, solvent control, and three groups given a series of curcumin concentrations: 10 µM, 50 µM, and 250 µM, separately. Survival assay and gene expression studies were carried out on these test groups.
Result: The results revealed that the lifespan of the curcumin-treated groups was significantly improved in comparison to the control groups. Such phenotype was accompanied by the increased expression of srl and hsp22 genes in most, if not all, of the curcumin-treated groups and elevated expression of tom40, pepck, and cat genes was specifically detectable only in groups treated with 250 µM curcumin. On the contrary, the expression of indy was significantly reduced upon the administration of curcumin at all given concentrations.
Conclusion: Based on these results, it can be inferred that supplementation of curcumin can improve the lifespan of the PGRP-LB mutant flies and this might be related to the changes in the expression of ageing-related genes.
PENINGKATAN POTENSI AIR GAMBUT SEBAGAI AIR BAKU (STUDI KASUS: KEBUN RAYA SRIWIJAYA SUMATERA SELATAN)
Authors: Ubaidillah Achmad , Faizal Muhammad , Napoleon A 
Published: May 2023

Air merupakan kebutuhan pokok bagi manusia khususnya air bersih. Salah satu cara pemenuhan kebutuhan air adalah menggunakan sumur bor. Namun, air sumur bor seringkali tidak memenuhi persyaratan air bersih, seperti mengandung zat besi (Fe) dan Mangan (Mn) yang cukup tinggi sehingga berdampak pada gangguan kesehatan dan merusak lingkungan. Kebun Raya Sriwijaya (KRS) berlokasi di wilayah rawa gambut sehingga sulit didapatkan air bersih. Air bersih di Kebun Raya Sriwijaya didapatkan dari sumur bor. Tujuan penelitian ini mengkaji kualitas air baku pada sumur bor di Perkantoran Kebun Raya Sriwijaya. Sampel dianalisa sesuai standar baku air bersih meliputi parameter TSS dengan metode uji SNI 6989.3-2019, pH dengan metode uji SNI 6989.11-2019, COD dengan metode uji SNI 6989.2-2019, BOD5 dengan metode uji SNI 6989.72-2019, ammonia bebas (NH3-N) dengan metode uji Spektrofotometri, sedangkan besi (Fe), mangan (Mn), dan fosfat (PO4) dengan metode SNI 6989.84-2019. Data hasil pengukuran kualitas air dibandingkan dengan standar baku mutu yang ditetapkan berdasarkan Permenkes RI/492/Menkes/Per/IV/2010 (Permenkes RI 2010), kemudian data dianalisa dengan metode deskriptif analitik. Dari hasil penelitian didapat konsentrasi COD, BOD5, besi (Fe), mangan (Mn) dan fosfat masih melebihi batas ambang yang diperbolehkan untuk air bersih menurut Permenkes RI/492/Menkes/Per/IV/2010. Diperlukan perlakuan terhadap air sumur bor disebelum digunakan, agar memenuhi standar air bersih sehingga layak digunakan.
PENERAPAN BUSINESS MODEL CANVAS (BMC) UNTUK PENINGKATAN NILAI EKONOMI PRODUK (STUDI KASUS:DEWAPONIK YOGYAKARTA)
Authors: Manalu Doni Sahat Tua , Tiofani Yesika Ardi , Sari Ayu Gupita 
Published: May 2023

Penelitian ini dilakukan untuk merumuskan dan menyusun ide perencanaan bisnis yang berfokus pada peningkatan nilai ekonomi produk dengan pendekatan Business Model Canvas (BMC) di Dewaponik Yogyakarta. Ditinjau berdasarkan sembilan elemen pada Business Model Canvas. Jenis penelitian yang digunakan yaitu penelitian kualitatif dan kuantitatif. Data primer dan data sekunder dikumpulkan melalui proses wawancara dan pencatatan. Hasil penelitian memberikan gambaran tentang kondisi bisnis pada Dewaponik dan beberapa rekomendasi yang dapat disarankan dilihat dari sembilan segmen pada Customer segments berupa perluasan pasar terhadap konsumen di wilayah Yogyakarta, Solo, dan sekitarnya, dengan menambahkan Tiktok dalam kegiatan pemasaran pada Key Acitvites, penggunaan sosial media pada Channels, memberikan kemudahan konsumen dalam mengakses informasi dan promosi pada Value Proposition, bertambahnya tempat untuk memberikan informasi dan promosi pada Customer Relationships, penambahan sumber daya manusia pada Key Resources, penambahan serta peningkatan mitra pada Key Partnerships, peningkatan penjualan sayur hidroponik pada Revenue Streams, pembukuan keuangan yang digunakan yaitu analisis laba rugi dan R/C Ratio pada Cost Structure. Berdasarkan analisis yang dilakukan, diperoleh bahwa terjadi peningkatan pendapatan di Dewaponik Yogyakarta.
Multiple ultrafast shunt failure in oncological COVID-19 pediatric patient
Authors: Ortega-Angulo Celia , Carceller Fernando , Vivancos Catalina , Medrano Alberto , Zamorano Jorge , Saceda Javier 
Published: May 2023

Introduction: Ventriculoperitoneal shunts (VPS) are one the most frequents interventions performed in Pediatric Neurosurgery, but their failure rate continues to be high. A relation between early and repeated VPS failure and the characteristics of cerebrospinal fluid (CSF) has been previously described, and there have also been reports of alterations in CSF due to coronavirus infectious disease (COVID-19).
Case presentation: A ten-year-old girl with a low grade thalamic glioma previously treated with two partial resections, chemotherapy and proton beam radiotherapy, developed hydrocephalus with intracranial hypertension. After emergent management with external ventricular drain, a VPS shunt with a programmable valve was implanted. The patient was diagnosed of COVID-19 in between these two procedures. Afterwards, she suffered from multiple shunt complications, with several events of obstruction. Her CSF had always very high protein concentration and COVID-19 tests were persistently positive.
Discussion: Obstruction is the main cause of VPS malfunction in children, and many studies have tried to elucidate risk factors for failure, as younger age or type of shunt. High protein concentration and cells count in CSF could influence shunt failure, but evidence is controversial. Moreover, COVID19 could also be related to such CSF alterations.
Conclusion: Early and repeated shunt failures are a clinical problem with no clear treatment stablished. Many factors can be associated to such complications, including CSF alterations, which may also be related to COVID19. Evidence is scarce and contradictory in many aspects, and pediatric neurosurgeons have to face this problem frequently, so more studies with management recommendations are needed.
Kajian Ketersediaan Ruang Terbuka Hijau Publik Non Alami Di Kota Manado
Authors: Budhyowati Noorwahyu 
Published: May 2023

Ruang Terbuka Hijau (RTH) sangat penting bagi kualitas dan kelangsungan kehidupan manusia, baik masa kini maupun di masa datang, kurangnya RTH menyebabkan penurunan kualitas udara dan juga turut menyebabkan suhu udara perkotaan menjadi semakin tinggi, karena suhu yang berada di zona tidak nyaman bagi manusia dapat juga menyebabkan perubahan perilaku warga kota dan yang akhirnya diatasi dengan menggunakan sistem pengkondisian udara (Air Conditioning) akhirnya kehidupan menjadi tidak hemat energi, karena hal ini, dirasa perlu untuk mengkaji ketersediaan RTH yang ada di Manado terutama RTH publik non alami, mengenai luasan dan fungsi RTH, terhadap kesesuaian dengan ketentuan yang ditetapkan dalam Peraturan Menteri (Permen) PU no.05/PRT/M/2008. Penelitian ini merupakan penelitian kuantitatif, penelitian dilakukan di Manado yaitu di Lapangan Sparta Tikala, Taman Kesatuan Bangsa Wenang, dan Lapangan KONI Sario. Pengumpulan data diawali dengan identifikasi terhadap data-data yang dibutuhkan dalam proses penelitian. Data yang digunakan dibagi atas dua yaitu data primer yang merupakan data utama yang digunakan dalam proses analisis dan data sekunder yaitu data yang digunakan sebagai standar dan pedoman dalam analisis. Pengumpulan data/informasi dilakukan dengan cara survey lapangan, membuat kuesioner, dan wawancara dengan responden juga studi literatur mengenai Ruang Terbuka Hijau terutama Ruang Terbuka Hijau Publik non alami. Pengolahan data menggunakan metode analisis statistik deskriptif. Kerangka Rancangan Penelitian dibuat untuk mencapai tujuan penelitian, yang terdiri dari tahap awal penelitian berupa latar belakang dan perumusan masalah, tujuan, dan kajian pustaka. Tahap proses penelitian berupa pengumpulan data/informasi, analisis, dan hasil penelitian dan tahap akhir yaitu kesimpulan.
Tinjauan Perencanaan Fasilitas Penunjang Ruang Terbuka Hijau (RTH) di Perumahan Relokasi Pandu Kota Manado
Authors: Rurut Randy Y. , Rachmawati Puput F. , Narasi Ni Kadek , Rogahang Rivaldo Jacky , Supit Steve , Sari Dian Puspita 
Published: May 2023

Perencanan ruang terbuka hijau (RTH) merupakan salah satu hal penting guna terciptanya kawasan yang memiliki aspek kenyamanan dan sehat bagi mereka yang tinggal serta lingkungan sekitarnya. Penelitian ini meninjau perencanaan RTH di lokasi Perumahan Relokasi Bencana di Pandu, Kota Manado dengan untuk memberikan rekomendasi kepada pemerintah dan masyarakat tentang pentingnya perencanaan dan konsep konstruksi penunjang ruang terbuka hijau di lokasi tersebut. Adapun konsep luaran adalah berupa perencanaan sistem ruang terbuka hijau pada tiap rumah di Perumahan Relokasi Pandu dengan 1 model rumah yang telah dibangun digunakan sebagai acuan perencanaan. Metode penelitian yang digunakan adalah deskriptif kualitatif dan deskriptif analisis pada objek penelitian. Sumber data yang dikumpulkan di dalam penelitian ini berupa data sekunder dan juga data primer. Data primer diperoleh melalui pengamatan observasi, sedangkan data sekunder diperoleh dari data-data informasi tentang Perumahan Relokasi Pandu. Metode penelitian deskriptif analisis menggunakan pendekatan pada kebutuhan RTH di Perumahan Relokasi Pandu yang dijadikan variabel penelitian. Adapun perencanaan fasilitas RTH ini dilakukan dengan menggunakan bantuan aplikasi Autocad dan Sketchup. Dari hasil penelitian disimpulkan bahwa perencanaan desain konstruksi rumah pada Perumahan Relokasi Pandu sangat diperlukan dengan mempertimbangkan variabel kebutuhan ruang terbuka hijau pada tiap rumah berupa sumur resapan, bak kontrol, taman vertikal, dan biopori.
Kajian Garis Sempadan Bangunan Pada Koridor Jalan Raya Kawasan Pusat Kota Tomohon
Authors: Tombeg Beldie Aryona , Mait Rudolf , Sulangi Charles , Mantiri Nixon 
Published: May 2023

Abstrak
Perkembangan pembangunan yang begitu cepat di kawasan pusat kota Tomohon menyebabkan ketidaksesuaian garis Sempadan Bangunan dengan peraturan yang ada. Selain mengurangi estetika, dapat pula mengganggu dan membahayakan para pengguna jalan yang beraktifitas. Tujuan dilakukan penelitian ini adalah untuk mengidentifikasi dan menganalisa ketidaksesuaian Garis Sempadan Bangunan yang ada pada koridor Jalan Raya Tomohon kawasan Pusat Kota Tomohon berdasarkan aturan dan dan kebijakan yang telah ditetapkan sehingga dapat terumuskan rekomendasi yang ideal dan sesuai aturan berlaku dalam rangka penataan bangunan dan lingkungan pada kawasan ini khususnya penataan garis sempadan bangunan. Metode penelitian ini menggunakan analisis deskriptif kualitatif, dimana data diperoleh melalui hasil observasi serta dokumentasi. Kesimpulan pada penelitian ini menunjukkan bahwa kepatuhan masyarakat umum terhadap terhadap aturan garis sempadan bangunan dalam membangun gedung baru ataupun melakukan renovasi masih sangat minim. Pada empat segmen objek penelitian menunjukkan bahwa kesesuaian garis sempadan bangunan paling banyak dilakukan oleh badan/organisasi pemerintah dan swasta seperti rumah sakit, gedung sekolah serta pelaku usaha seperti Ruko/Toko.

Kata Kunci : Pembangunan, Garis Sempadan Bangunan, Ketidaksesuaian, Kota Tomohon