bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gender Differences in Social Support and Posttraumatic Growth for Survivors of Intimate Partner Violence
Authors: Cundiff Justice M. , Fromuth Mary Ellen , Fuller Dana K. 
Published: January 2023

The current study investigated gender differences in perceived social support and posttraumatic growth for survivors of intimate partner violence. Participants for this study included 86 undergraduate students who indicated at least one instance of partner abuse (consisting of physical abuse, sexual abuse, emotional abuse, and harassment). Participants were predominantly female (68%), White/Caucasian (62%), and between 18 and 21 years of age (84%). Participants responded to the Multidimensional Scale of Perceived Social Support, the Composite Abuse Scale, and the Posttraumatic Growth Inventory. Mean differences and correlational analyses were utilized to investigate potential gender differences in the study variables as well as the relationships among them. The prevalence of intimate partner violence was comparable to those found in other studies, with 59% of men and 57% of women indicating experiencing abuse from a partner. Although the prevalence rates were similar, women indicated higher overall partner abuse victimization than did men. Moreover, women indicated statistically significantly higher scores than men in three of the four Composite Abuse Scale subscales, reflecting higher levels of victimization for all forms of abuse except for partner harassment. Further, perceived social support scores were similar for men and women, with the only significant gender difference to emerge being that men indicated higher levels of familial support than did women. No statistically significant gender differences emerged for overall posttraumatic growth or for any of its domains. Finally, social support was correlated with posttraumatic growth for women but not for men. The current study, therefore, suggests that men and women may experience similar levels of personal growth in the aftermath of partner abuse. Moreover, these results imply that the relationship between social support and posttraumatic growth may vary according to the gender of the survivor.
Survival impact of unexpected N2 in stage IIIB/N2 non-small cell lung cancer patients
Authors: Erdoğu Volkan , Çıtak Necati , Sezen Celal Buğra , Kizir Dilekhan , Tanrıkulu Gamze , Doğru Mustafa Vedat , Seyrek Yunus , Cansever Levent , Saydam Özkan , Metin Muzaffer 
Published: January 2023

Background We investigated the effect of unexpected N2 on survival in stage IIIB/N2 cases. Methods We retrospectively analyzed 1803 non-small cell lung cancer patients between 2010 and 2016. There were 89 patients (4.9%) with unexpected N2 (pathological (p) IIIB/N2 group), whereas 49 patients (2.7%) with cN2 (clinical (c) IIIB/N2 group). Although pIIIB/N2 group underwent surgery followed by adjuvant therapy, the cIIIB/N2 group of patients had multimodality treatment including induction chemotherapy ± radiotherapy followed by surgery. Results The five-year overall survival (OS) for all patients was 36.0% [median survival time (MST) 27.9 months], and disease-free survival (DFS) was 28.9% (MST, 18.2 months). The OS was 39.6% (MST: 34.4 months) and the median DFS time was 31.1% (Median: 23.1 months) in the pIIIB/N2 group, whereas it was 29.2% (MST: 23.0 months) for OS and 22% (median: 12.4 months) for DFS in the cIIIB/N2 group. There were no significant OS and DFS differences between the pIIIB/N2 group and the cIIIB/N2 group ( p = 0.124 and p = 0.168, respectively). Conclusions In stage IIIB/N2 cases, the fact that N2 could not be detected preoperatively with minimally invasive or invasive methods and was detected in the pathological examination after surgery does not provide a survival advantage.
Shared responsibility for decision-making in NICU: A scoping review
Authors: Pellikka Hanna-Kaisa , Axelin Anna , Sankilampi Ulla , Kangasniemi Mari 
Published: January 2023

Background Shared responsibility is an essential part of family-centred care and it characterizes the relationship between parents and healthcare professionals. Despite this, little is known about their shared responsibility for decision-making in neonatal intensive care units. Aim The aim of this scoping review was to identify previous studies on the subject and to summarize the knowledge that has been published so far. Method The review was conducted using electronic searches in the CINAHL, PubMed, Scopus and PsycINFO databases and manual searches of the reference lists of the selected papers. The searches were limited to peer-reviewed papers that had been published in English from 2010 to September 2021. The data were selected based on inclusion and exclusion criteria and the findings were inductively summarized. We identified eight papers that met the inclusion criteria. Ethical considerations: The scoping review was conducted according to good scientific practice by respecting authorship and reporting the study processes accurately, honestly and transparently. Results The results showed that shared responsibility for decision-making was based on the parents’ intentions, but the degree to which they were willing to take responsibility varied. The facilitating and inhibiting factors for shared responsibility for decision-making were related to the communication between parents and professionals. The impact was related to the parents’ emotions. Conclusion It is essential that parents and professionals negotiate how both parties will contribute to their shared responsibility for decision-making. This will enable them to reach a mutual understanding of what is in the infants’ best interests and to mitigate the emotional burden of decisions in neonatal intensive care units. More research is needed to clarify the concept of shared responsibility for decision-making in this intensive care context.
Enhancing an online cognitive behavioural therapy intervention for depression: Harnessing the feedback of sexual and gender minority youth to help improve SPARX
Authors: Lucassen Mathijs FG , Stasiak Karolina , Fleming Theresa , Shepherd Matthew , Merry Sally N 
Published: January 2023

Objective SPARX is an online cognitive behavioural therapy self-help intervention for adolescent depression provided in serious game format. Since 2014, it has been freely available in Aotearoa New Zealand (NZ) due to funding from the NZ government. In 2020/21, feedback from sexual and gender minority youth (SGMY) was used to refine and update SPARX. Method Three online focus groups and follow-up email consultations involved 12 SGMY (16 to 25 years old) in NZ. A general inductive approach was used to analyse data. Results SGMY had specific needs as well as preferences and four themes were identified: attend to our contextual realities; portrayals of sexual and gender minority people in games; envisaged ideals for serious gaming and appraisals of SPARX. SGMY feedback was used to improve SPARX for this unique population, with the updates launched in October 2021. Conclusions SGMY are underserved in terms of their mental health needs. Refining or tailoring existing interventions proffers a potential way forward in terms of addressing these needs.
Serum Krebs von den Lungen-6 for Predicting the Severity of COVID-19: A Systematic Review, Meta-Analysis, and Trial Sequence Analysis
Authors: Shrestha Abhigan Babu , Pokharel Pashupati , Singh Harendra , Shrestha Sajina , Fioni  
Published: January 2023

OBJECTIVE This systematic review and meta-analysis aimed to find the association between serum Krebs von den Lungen-6 (KL-6) and the severity of Coronavirus disease 2019 (COVID-19) infection. DATA SOURCES Databases of Embase, PubMed, Web of Science, Science Direct, and Google Scholar were searched for studies reporting KL-6 levels in COVID-19 patients, published between January 2020 and September 30 2022. DATA SYNTHESIS For comparison between the groups, standard mean difference (SMD) and 95% confidence intervals (CI) were computed as the effect sizes. Sensitivity, specificity, positive likelihood ratio (PLR), and negative likelihood ratio (NLR) were measured to assess the diagnostic power of KL-6. In addition, the summary receiver operating characteristics curve (sROC) was constructed to summarize the true positive (TP), and false positive (FP) rates. To validate the findings of meta-analysis, Trial Sequential Analysis (TSA) was conducted. RESULTS Altogether 497 severe COVID-19 patients and 934 non-severe (mild to moderate) COVID-19 patients were included. Pooling of 12 studies indicated that the serum KL-6 level had significant association with severity of COVID-19 infection: standard mean difference = 1.18 (95% CI: 0.93-1.43), p = 0.01; I2: 58.56%]. Pooled diagnostic parameters calculated from eight studies were: sensitivity 0.53 (95% CI: 0.47-0.59); specificity 0.90 (95% CI: 0.88-0.93); positive likelihood ratio 4.80 (95% CI: 3.53-6.53); negative likelihood ratio 0.46 (95% CI: 0.32-0.68); and area under curve: 0.8841. Additionally, TSA verified the adequacy of sample size and robustness of the meta-analysis. CONCLUSION Serum KL-6 level has a moderate degree of correlation with the severity of COVID-19 infection but has low sensitivity. So, it is not recommended as a screening test for severe COVID-19 infection.
Understanding Financial Toxicity in Patients with Head and Neck Cancer: A Systematic Review
Authors: Rosi-Schumacher Mattie , Patel Shivam , Phan Chandat , Goyal Neerav 
Published: January 2023

Background: Cancer treatment often results in financial burdens for patients including healthcare costs as well as treatment-induced disability leading to “financial toxicity” (FT) and decreased quality of life. The purpose of this review is to describe FT related to head and neck cancer (HNC) treatment, including quantifications of direct and indirect costs and descriptions of measurement tools. Methods: PubMed, Embase, Cochrane Library, and Web of Science databases were searched to identify articles published before April 2022. Full-text published studies were included if they assessed direct or indirect costs of HNC treatment; studies were excluded if they did not focus on HNC or financial burden. The risk of bias was assessed, and the results of the studies were synthesized. Results: Database searches yielded 530 unique studies, and 33 studies met the criteria for inclusion. Medical expenses for patients with HNC were higher than for patients with other cancers or controls in several studies. Major surgical procedures, neck dissection, free-flap reconstruction, and intensive care unit admission increased hospital costs. Trimodal therapy with surgery plus chemoradiation represented the most expensive treatment, and chemoradiation increased complication-related health care costs. In several studies, >50% of patients treated for HNC were disabled and did not return to work. One of the greatest contributors to the indirect cost of HNC treatment is the loss of lifetime wages. Patients with HNC are at risk for depression, anxiety, and social isolation, which are linked to a decreased quality of life and treatment non-adherence. The only tools used to assess FT in patients with HNC are the Comprehensive Score for financial Toxicity (COST) and the Financial Index of Toxicity (FIT). Conclusion: Financial toxicity is highly prevalent among patients with HNC. Further research is needed to validate the assessment tools for quantifying FT in HNC patients.
Reliability and validity of the Autism Screen for Kids and Youth
Authors: Lavi Rachelle , Stokes Mark A 
Published: January 2023

Few instruments screen for autism spectrum disorder (ASD) among kindergarteners and older children. The Autism Screen for Kids and Youth (ASKY) is a 30-item parental questionnaire for 4- to 18-year-old children and adolescents available in Arabic, English, and Hebrew. We examined the sensitivity, specificity, and temporal stability of the Hebrew ASKY’s categorizations (“probable ASD” versus “probable non-ASD”) of 167 autistic and non-autistic 4- to 18-year olds. Algorithm-based categorization following The Diagnostic and Statistical Manual of Mental Disorders: Fifth Edition ( DSM-5) rules demonstrated 91.8% sensitivity, 71.7% specificity, and excellent test–retest reliability (κ = 0.783, 95% confidence interval (CI) = 0.583–0.983, p < 0.001). Total score-based categorization using a cutoff of 9 demonstrated high receiver operating characteristics area under the curve (AUC = 0.874) and high sensitivity (93.4%), specificity (78.3%), internal consistency (Cronbach’s α = 0.954), and test–retest reliability (κscores = 0.674, κinstrument = 0.783). Discussing both categorization approaches, we show that the ASKY is a promising instrument for ASD screening of older children. Lay Abstract It is important that autistic children be diagnosed as early as possible so their needs can be met and their families can gain important insights into their behavior and interact with them appropriately. However, very few autism screening instruments are appropriate for children who have outgrown early childhood. The Autism Screen for Kids and Youth (ASKY) presents parents of children aged 4–18 years with 30 items that relate to autistic behaviors as defined by the current clinical diagnostic criteria for autism spectrum disorder ( DSM-5 ASD). We evaluated the Hebrew instrument’s performance on 167 autistic and non-autistic children and adolescents. We found that the ASKY algorithm correctly identified 92% of the autistic individuals as “probable ASD” and correctly identified 72% of the non-autistic individuals as “probable non-ASD,” with these classifications showing excellent stability over time. Using total questionnaire score instead of the algorithm improved the ASKY’s ability to correctly identify autistic individuals as “probable ASD” and non-autistic individuals as “probable non-ASD” to 93% and 78%, respectively. Overall, the ASKY is a promising instrument for ASD screening of older children.
Efficacy and Safety of East Asian Herbal Medicine for Brain Metastases in Non-small Cell Lung Cancer: A Systematic Review and Meta-analysis Protocol to Identify Specific Herbs
Authors: Xu Bowen , Ge Yuansha , Wang Heping , Zhang Xiaoxiao , Wu Jingyuan , Li Jie 
Published: January 2023

Introduction: Brain metastasis (BM) is a significant risk factor for survival and prognosis in non-small cell lung cancer (NSCLC). While surgical resection and radiotherapy are the primary treatment modalities, the overall prognosis in NSCLC patients with BM remains poor, and all therapies lead to adverse events. East Asian herbal medicine (EAHM) has broad prospects as an adjuvant treatment, but its efficacy and safety remain controversial. We propose to conduct a systematic review and meta-analysis to summarize the clinical efficacy and safety of EAHM for the treatment of NSCLC with BMs and to identify specific herbs that can improve the prognosis. Methods: The PubMed, EMBASE, CENTRAL, Web of Science, CBM, CNKI, Wanfang, VIP, Evidence Reports on Kampo Treatment, ICHUSHI, and Oriental Medicine Advanced Searching Integrated System databases will be searched from their inception to October 2022. Randomized controlled trials will be included. Two authors will evaluate the eligibility and quality of the included trials. The methodological quality will be assessed using the RoB 2 tool, and Stata 16 will be used for data synthesis. Publication bias will be assessed using funnel plots and Egger tests. The GRADE (Grading of Recommendations Assessment, Development, and Evaluation) system will evaluate the quality of the synthesized evidence. Further sensitivity analyses will be performed to determine the efficacies of specific herbs in EAHM. Discussion: Given there are currently no systematic reviews and meta-analyses of the efficacy of EAHM as a treatment for NSCLC with BMs, a compilation and analysis of the available high-quality clinical research evidence are essential. The results will help establish guidelines for the application of specific herbs as a complementary alternative therapy for BMs in NSCLC. The findings will be published in a peer-reviewed journal. PROSPERO registration number: CRD42022300527.
Treatment preferences in relation to fatigue of patients with relapsing multiple sclerosis: A discrete choice experiment
Authors: Tervonen Tommi , Fox Robert J , Brooks Anne , Sidorenko Tatiana , Boyanova Neli , Levitan Bennett , Hennessy Brian , Phillips-Beyer Andrea 
Published: January 2023

Background Treatment decisions for multiple sclerosis (MS) are influenced by many factors such as disease symptoms, comorbidities, and tolerability. Objective To determine how much relapsing MS patients were willing to accept the worsening of certain aspects of their MS in return for improvements in symptoms or treatment convenience. Methods A web-based discrete choice experiment (DCE) was conducted in patients with relapsing MS. Multinomial logit models were used to estimate relative attribute importance (RAI) and to quantify attribute trade-offs. Results The DCE was completed by 817 participants from the US, the UK, Poland, and Russia. The most valued attributes of MS therapy to participants were effects on physical fatigue (RAI = 22.3%), cognitive fatigue (RAI = 22.0%), relapses over 2 years (RAI = 20.7%), and MS progression (RAI = 18.4%). Participants would accept six additional relapses in 2 years and a decrease of 7 years in time to disease progression to improve either cognitive or physical fatigue from “quite a bit of difficulty” to “no difficulty.” Conclusion Patients strongly valued improving cognitive and physical fatigue and were willing to accept additional relapses or a shorter time to disease progression to have less fatigue. The impact of fatigue on MS patients’ quality of life should be considered in treatment decisions.
Isolated, Full-Thickness Proximal Rectus Femoris Injury in Competitive Athletes: A Systematic Review of Injury Characteristics and Return to Play
Authors: Knapik Derrick M. , Alter Thomas D. , Ganapathy Aravinda , Smith Matthew V. , Brophy Robert H. , Matava Matthew J. 
Published: January 2023

Background: Characteristics regarding mechanism of injury, management, and return-to-play (RTP) rate and timing are important when treating and counseling athletes with rectus femoris tears. Purpose: To systematically review the literature to better understand the prevalence, sporting activity, injury mechanisms, and treatment of patients with rectus femoris injury and to provide prognostic information regarding the rate and timing of RTP. Study Design: Systematic review; Level of evidence, 4. Methods: Following the 2020 PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, we queried PubMed/MEDLINE, Cochrane, OVID, EMBASE, and Google Scholar in March 2022 for studies reporting on athletes sustaining isolated, full-thickness tearing, or bony avulsion injuries to the proximal rectus femoris during sporting activity. Excluded were studies without evidence of full-thickness tearing or avulsion, with athletes sustaining concomitant injuries, or with injuries occurring from nonsporting activities. The percentage of athletes sustaining injuries was calculated based on sport, injury mechanism, and management (nonoperative versus operative). Results: Of 132 studies initially identified, 18 were included, comprising 132 athletes (mean age, 24.0 ± 5.4 years; range, 12-43 years). The most common sporting activities were soccer (70.5%) and rugby (15.2%). The most reported mechanisms of injury were kicking (47.6%) and excessive knee flexion/forced hip extension (42.9%). Avulsion injuries were reported in 86% (n = 114) of athletes. Nonoperative management was reported in 19.7% of athletes, with operative management performed in 80.3%. The mean follow-up time was 21.4 ± 11.4 months (range, 1.5-48 months). The RTP rate was 93.3% (n = 14) in nonoperatively treated and 100% (n = 106) in operatively treated athletes, and the mean RTP time was 11.7 weeks (range, 5.5-15.2 weeks) in nonoperatively treated and 22.1 weeks (range, 14.0-37.6 weeks) in operatively treated athletes. Complications were reported in 7.7% (2/26) of nonoperatively treated and 18% (n = 19/106) of operatively treated athletes. Conclusion: Full-thickness proximal rectus femoris injuries occurred most frequently in athletes participating in soccer and rugby secondary to explosive, eccentric contractions involved in kicking and sprinting. Operative management was performed in the majority of cases. Athletes who underwent operative repair had a 100% RTP rate versus 93.3% in athletes treated nonoperatively.
A Compensation Algorithm for Large Element Characterizing the Damage Evolution Process and Its Application to Structure Collisions
Authors: Liu Wen , Zhang Lele , Ru Yifan , Chen Geng , Dou Weiyuan 
Published: January 2023

AbstractWhen simulating the process from elastic–plastic deformation, damage to failure in a metal structure collision, it is necessary to use the large shell element due to the calculation efficiency, but this would affect the accuracy of damage evolution simulation. The compensation algorithm adjusting failure strain according to element size is usually used in the damage model to deal with the problem. In this paper, a new nonlinear compensation algorithm between failure strain and element size was proposed, which was incorporated in the damage model GISSMO (Generalized incremental stress state dependent damage model) to characterize ductile fracture. And associated material parameters were calibrated based on tensile experiments of aluminum alloy specimens with notches. Simulation and experimental results show that the new compensation algorithm significantly reduces the dependence of element size compared with the constant failure strain model and the damage model with the linear compensation algorithm. During the axial splitting process of a circular tubular structure, the new compensation algorithm keeps the failure prediction errors low over the stress states ranging from shear to biaxial tension, and achieves the objective prediction of the damage evolution process. This study demonstrates how the compensation algorithm resolves the contradiction between large element size and fracture prediction accuracy, and this facilitates the use of the damage model in ductile fracture prediction for engineering structures.