bluuebunny/crossref_metadata_2025_split huggingface dataset:
Differences in solitary and dyadic sexual desire and sexual satisfaction in heterosexual and nonheterosexual cisgender men and women
Authors: Peixoto Maria Manuela 
Published: March 2023

Abstract

Background
Gender differences in sexual desire have been documented in the literature, with sexual desire being correlated with sexual satisfaction; however, data on sexual desire and sexual satisfaction among nonheterosexual samples are more limited, as are data examining sexual desire toward oneself (solitary) and another person (dyadic).

Aim
To examine differences between men and women, between heterosexuals and nonheterosexuals, and the interaction of gender and sexual orientation in solitary and dyadic sexual desire (partner and attractive person related) and sexual satisfaction, and to explore the predictive role of solitary and dyadic sexual desire on sexual satisfaction, controlling for gender and sexual orientation.

Methods
A cross-sectional study was conducted with an online sample of 1013 participants recruited between 2017 and 2020 (552 women, 54.5%; 461 men, 45.5%; 802 heterosexuals, 79.2%; 211 nonheterosexuals, 20.8%).

Outcomes
Participants completed a web survey with a sociodemographic sheet, the Sexual Desire Inventory–2, and the Global Measure of Sexual Satisfaction.

Results
Current findings indicated that men scored significantly higher on solitary sexual desire (P &lt; .001, partial η2 = 0.015) and attractive person–related desire (P &lt; .001, partial η2 = 0.015) when compared with women. Likewise, nonheterosexuals scored significantly higher on solitary sexual desire (P &lt; .001, partial η2 = 0.053) and attractive person–related desire (P &lt; .001, partial η2 = 0.033) vs heterosexuals. In addition, partner-related desire (β = 0.33, P &lt; .001) was a positive and significant predictor of sexual satisfaction, whereas solitary desire (β = −0.18, P &lt; .001) and attractive person–related desire (β = −0.23, P &lt; .001) were negative predictors.

Clinical Implications
Sexual desire toward an intimate partner appears to be experienced in similar levels among heterosexual and nonheterosexual men and women, while solitary and attractive person–related sexual desire appears to be more strong among men and nonheterosexual individuals.

Strengths and Limitations
The current study did not use a dyadic-centered approach, only individual perceptions and experiences. However, it explored solitary sexual desire and partner– and attractive person–related sexual desire in a large sample of heterosexual and nonheterosexual men and women as predictors of sexual satisfaction.

Conclusion
Overall, men and nonheterosexual individuals experienced more solitary and attractive person–related sexual desire. In addition, partner–related sexual desire was a positive predictor of sexual satisfaction, whereas solitary sexual desire and attractive person–related desire were negative predictors of sexual satisfaction.
Efficacy of laser interstitial thermal therapy for biopsy-proven radiation necrosis in radiographically recurrent brain metastases
Authors: Chan Michael , Tatter Steven , Chiang Veronica , Fecci Peter , Strowd Roy , Prabhu Sujit , Hadjipanayis Constantinos , Kirkpatrick John , Sun David , Sinicrope Kaylyn , Mohammadi Alireza M , Sevak Parag , Abram Steven , Kim Albert H , Leuthardt Eric , Chao Samuel , Phillips John , Lacroix Michel , Williams Brian , Placantonakis Dimitris , Silverman Joshua , Baumgartner James , Piccioni David , Laxton Adrian 
Published: March 2023

Abstract

Background
Laser interstitial thermal therapy (LITT) in the setting of post-SRS radiation necrosis (RN) for patients with brain metastases has growing evidence for efficacy. However, questions remain regarding hospitalization, local control, symptom control, and concurrent use of therapies.

Methods
Demographics, intraprocedural data, safety, Karnofsky performance status (KPS), and survival data were prospectively collected and then analyzed on patients who consented between 2016–2020 and who were undergoing LITT for biopsy-proven RN at one of 14 US centers. Data were monitored for accuracy. Statistical analysis included individual variable summaries, multivariable Fine and Gray analysis, and Kaplan–Meier estimated survival.

Results
Ninety patients met the inclusion criteria. Four patients underwent 2 ablations on the same day. Median hospitalization time was 32.5 hours. The median time to corticosteroid cessation after LITT was 13.0 days (0.0, 1229.0) and cumulative incidence of lesional progression was 19% at 1 year. Median post-procedure overall survival was 2.55 years [1.66, infinity] and 77.1% at one year as estimated by KaplanMeier. Median KPS remained at 80 through 2-year follow-up. Seizure prevalence was 12% within 1-month post-LITT and 7.9% at 3 months; down from 34.4% within 60-day prior to procedure.

Conclusions
LITT for RN was not only again found to be safe with low patient morbidity but was also a highly effective treatment for RN for both local control and symptom management (including seizures). In addition to averting expected neurological death, LITT facilitates ongoing systemic therapy (in particular immunotherapy) by enabling the rapid cessation of steroids, thereby facilitating maximal possible survival for these patients.
Oral iron replacement vs. IV iron treatment in bariatric surgery patients with anemia
Authors: Connors Angelyn , Watkins Elyse J. 
Published: March 2023

ABSTRACT
Bariatric surgery has become a recognized tool to reduce weight and resolve or improve comorbid conditions associated with obesity. Patients with obesity are at risk for nutritional deficiencies because of poor-quality diets and the chronic inflammatory state of obesity. Iron deficiency is common in these patients, with incidence rates as high as 21.5% preoperatively and 49% postoperatively. Iron deficiency is often overlooked and not treated, leading to increased complications. This article reviews the risk factors for developing iron-deficiency anemia, diagnosis, and treatment considerations for oral versus IV iron replacement for patients undergoing bariatric surgery.
Botulinum neurotoxin
Authors: Aldridge Jamie H. R. 
Published: March 2023

ABSTRACT

Clostridium botulinum is a Gram-positive bacterium that produces one of the most deadly chemodenervating toxins in the world. To date, six distinct neurotoxins are available for prescription use in the United States. Decades of data across aesthetic therapeutic areas and therapeutic disease states support the safety and efficacy of C. botulinum, providing good symptom management and improved quality of life in appropriately chosen patients. Unfortunately, many clinicians are slow to progress patients to toxin therapy from more conservative measures, and others wrongly interchange the products despite characteristics unique to each. Commensurate with an improved understanding of the complex pharmacology and clinical implications of botulinum neurotoxins is the importance for clinicians to appropriately identify, educate, refer, and/or treat candidate patients. This article provides an overview of the history, mechanism of action, differentiation, indications, and uses for botulinum neurotoxins.
Clinical update on dementia with Lewy bodies for primary care NPs
Authors: Parish Abby Luck , Kim Jennifer 
Published: March 2023

Abstract:
Dementia with Lewy bodies is the second most common type of neurodegenerative dementia in older adults. NPs in primary care must have a thorough understanding of this complex disease in order to ensure appropriate referrals, provide patient and caregiver education, and comanage this disease with other healthcare professionals.
Development of objective performance metrics for ultrasound-guided internal jugular vein cannulation on behalf of the College of Anaesthesiologists of Ireland and observation of scores amongst novice and experienced operators
Authors: Breen Dorothy , Farrelly Sean , Condon Eilis , Armstrong Cathy , Doody Kevin , Duggan Michelle , Gallagher Anthony G. 
Published: March 2023

BACKGROUND
Ultrasound-guided, internal jugular venous (IJV) cannulation is a core technical skill for anaesthesiologists and intensivists.

OBJECTIVES
At a modified Delphi panel meeting, to define and reach consensus on a set of objective ultrasound-guided IJV cannulation performance metrics on behalf of the College of Anaesthesiologists of Ireland (CAI). To use these metrics to objectively score video recordings of novice and experienced anaesthesiologists.

DESIGN
An observational study.

SETTING
CAI, March to June 2016 and four CAI training hospitals, November 2016 to July 2019.

PARTICIPANTS
Metric development group: two CAI national directors of postgraduate training (specialist anaesthesiolgists), a behavioural scientist, a specialist intensivist and a senior CAI trainee. Scoring by two blinded assessors of video recordings of novice (n = 11) and experienced anaesthesiologists (n = 15) ultrasound-guided IJV cannulations.

MAIN OUTCOME MEASURES
A set of agreed CAI objective performance metrics, that is, steps, errors, and critical errors characterising ultrasound-guided IJV cannulation. The difference in performance scores between novice and experienced anaesthesiologists as determined by skill level defined as being below or above the median total error score (errors plus critical errors): that is, low error (LoErr) and high error (HiErr), respectively.

RESULTS
The study identified 47 steps, 18 errors and 13 critical errors through six phases.
Variability was observed in the range of total error scores for both novice (1 to 3) and experienced (0 to 4.5) anaesthesiologists. This resulted in two further statistically different subgroups (LoErr and HiErr) for both novice (P = 0.011) and experienced practitioners (P < 0.000). The LoErr-experienced group performed the best in relation to steps, errors and total errors. Critical errors were only observed in the experienced group.

CONCLUSION
A set of valid, reliable objective performance metrics has been developed for ultrasound-guided IJV cannulation. Considerable skill variability underlines the need to develop a CAI simulation-training programme using these metrics.
Temporary Pupil Occlusion and Retrolenticular Air Bubble Injection for Descemet Membrane Endothelial Keratoplasty in Vitrectomized Unicameral Eyes
Authors: Seong Jueun , Shim Kyu Young , Jun Jong Hwa 
Published: March 2023

Purpose:
The aim of this study was to describe a surgical method that can be easily and safely performed during Descemet membrane endothelial keratoplasty in patients who had previously undergone pars plana vitrectomy with transscleral fixation of the intraocular lens.

Methods:
This report reviewed 2 Descemet membrane endothelial keratoplasty procedures performed in patients with vitrectomized unicameral eyes. The proposed technique is characterized by the temporary suture of the pupillary aperture to block the forward flow of vitreous humor and prevent the abrupt loss of air tamponade due to backward movement of the air bubble into the vitreous cavity. At the same time, another air bubble is injected behind the scleral-fixated intraocular lens to induce forward movement of the iris–intraocular lens diaphragm through buoyancy. Thus, the depth of the anterior chamber is reduced, allowing easier unscrolling of the Descemet membrane endothelial keratoplasty lenticule.

Results:
Pupil closure and buoyancy of the air bubble allow the anterior chamber to be separated from the inflow of vitreous cavity fluid and maintained adequately shallow. During the keratoplasty, the graft is then easily unscrolled without the support of the capsular diaphragm. Postoperatively, the air bubble is maintained in the anterior chamber for a sufficient period. Nd:YAG laser suture lysis is performed after complete absorption of the air bubble during outpatient follow-up.

Conclusions:
Temporary pupil occlusion and retrolenticular air bubble injection provide a stable surgical approach in challenging cases of postvitrectomized unicameral eyes.
Hepatitis E virus: has anything changed?
Authors: Willauer Alexandra N. , Sherman Kenneth E. 
Published: March 2023

Purpose of review
Infection with hepatitis E virus (HEV) is a global health concern, yet a clinically underdiagnosed cause of acute and chronic hepatitis. The WHO estimates that 20 million people are infected with HEV annually, yet the epidemiology, diagnosis and prevention remain elusive in many clinical settings.

Recent findings

Orthohepevirus A (HEV-A) genotypes 1 and 2 cause acute, self-limited hepatitis through faecal-oral transmission. In 2022, the first-ever vaccine campaign was implemented as a response to an HEV outbreak in an endemic region. HEV-A genotypes 3 and 4 are zoonotic infections that primarily cause chronic HEV infection in immunosuppressed populations. Pregnant women and immunocompromised persons are at high risk for severe illness in some settings. Another recent advance in our knowledge of HEV is the zoonotic transmission of Orthohepevirus C (HEV-C) to humans, presumably from contact with rodents and/or their excrement. Previously, HEV infection in humans was presumed to be limited to HEV-A only.

Summary
Clinical recognition and accurate diagnosis are essential to the management of HEV infection and understanding the global burden of the disease. Epidemiology affects clinical presentations. Targeted response strategies in HEV outbreaks are needed for the prevention of disease, and vaccine campaigns may prove to be an effective part of these strategies.
The establishment mode of Chinese MNEs abroad and the Belt and Road Initiative: insights from a strategy tripod perspective
Authors: Quer Diego 
Published: March 2023

PurposeEmerging-market multinational enterprises (MNEs) have pushed institutional factors to the cutting-edge of international business research. As for Chinese MNEs, the importance of institutions has been strengthened since the Chinese government launched the Belt and Road Initiative (BRI), which seeks to promote a comprehensive platform for cooperation among countries. This study aims to investigate the role played by the BRI as an institutional factor moderating the influence of other institution-, industry- and firm-specific factors on establishment mode choice by Chinese MNEs.Design/methodology/approachDrawing on the strategy tripod, a perspective claiming that a firm's strategies are the result of internal, industrial and institutional conditions, this study develops a number of hypotheses that are tested with data on 1,076 outward foreign direct investments (OFDIs) of Chinese MNEs between 2013 and 2021.FindingsThe results show that the BRI moderates the influence of both the firm's prior international acquisition experience and Chinese government's OFDI restrictions on the establishment by means of an acquisition. They also report that this moderating effect does not apply for acquisition experience in the host country nor institutional distance.Originality/valueThis study contributes to reinforce the importance of institutions as the third leg of a strategy tripod when explaining international behavior of Chinese MNEs. It also suggests that the BRI is a diplomatic tool that may act as a substitute for the firm's resources and may mitigate the negative influence of other external factors.
Investigating the relationship between corporate social responsibility implementation and contractor competitiveness
Authors: Nguyen Minh Van 
Published: March 2023

PurposeThis study aims to (1) develop a structural equation model in understanding the relationships between corporate social responsibility (CSR) performance and contractor competitiveness and (2) test the moderating effect of firm sizes on this relationship.Design/methodology/approachA literature review showed an urgent need to investigate the relationship between CSR implementation and contractor competitiveness holistically. CSR and contractor competitiveness variables were identified through the literature review and discussions with experienced professionals. Using a survey questionnaire, a total of 252 completed questionnaires were received. A structural equation modeling technique was then applied to analyze the data collected. Multigroup analysis was employed to test the moderating effect of firm sizes on the relationship between CSR implementation and contractor competitiveness.FindingsThe results indicated a strong relationship between CSR implementation and contractor competitiveness. This relationship is not moderated by firm size.Originality/valueThis research is one of the first studies to holistically explore the linkages between CSR implementation and contractor competitiveness. The findings can be served as a solid foundation to promote CSR performance in construction firms. Contractors of different sizes are suggested to implement CSR activities to foster competitiveness.
“We are experiencing pain on our own”: mental health care to prevail over impacts of cultural silence on HIV
Authors: Mwalabu Gertrude , Evans Catrin , Redsell Sarah , Petruka Pammla , Mapulanga Patrick 
Published: March 2023

Purpose
This qualitative case study aims to investigate how current services meet the emotional needs of young women growing up with perinatally acquired human immunodeficiency virus (HIV). Young women (15–19 years old), caregivers and service providers were recruited through three multidisciplinary HIV management centres in Malawi.

Design/methodology/approach
In-depth interviews were used to collect data for 14 “cases” (each “case” involved a young woman, a caregiver and a service provider, for a total of 42 participants). The interviews with adolescents were conducted using an innovative visual method known as the “my story” book.

Findings
Thematic analysis revealed that young women experienced traumatic experiences and emotional neglect after being diagnosed as HIV positive. Lack of adult support networks and social isolation were identified as intersecting factors contributing to their mental distress. According to the findings of this study, HIV care should more explicitly include comprehensive mental health-care services. This provision should include ongoing individualised counselling sessions, supplemented by communication skills training to help break the prevalent cultural silence on HIV issues. Young people living with HIV, in general, and young women, are more likely to experience mental health issues than their non-infected peers. Integrating comprehensive mental health evaluation and treatment into HIV care for young people can be beneficial.

Practical implications
Mental health issues are critical and underserved challenges among young people living with perinatally acquired HIV. Women experience a higher prevalence of mental challenges than men. Integrating comprehensive mental health evaluation and treatment into HIV care for young people can be beneficial. Therefore, interventions to assist young people with mental health issues are needed within the context of HIV management in Malawi.

Originality/value
Many studies on mental health and HIV/AIDS have been conducted. However, there is very little information as regards the emotional needs of young women growing up with perinatally acquired HIV. This study fills the void.
Previous pre‐eclampsia, gestational diabetes mellitus and the risk of cardiovascular disease: A nested case–control study in Sweden
Authors: Hildén Karin , Magnuson Anders , Montgomery Scott , Schwarcz Erik , Hanson Ulf , Simmons David , Backman Helena 
Published: March 2023

AbstractObjectivePre‐eclampsia and gestational diabetes mellitus (GDM) are two common pregnancy complications that affect birth outcomes and are associated with a long‐term risk of cardiovascular disease (CVD). The aims of this study were to investigate if the pre‐eclampsia association with CVD is independent of GDM and modified by body mass index (BMI) or GDM.DesignCase–control study.SettingSweden.PopulationCases were women with a first CVD event between 1991 and 2008 and a previous pregnancy who were matched with controls without CVD (1:5) by year of birth, age and region of birth.MethodsConditional logistic regression was used to evaluate the associations of GDM, pre‐eclampsia and maternal BMI with CVD adjusted for potential confounders and effect modifications with interaction tests.Main outcome measuresCVD.ResultsThere were 2639 cases and 13 310 controls with complete data. Pre‐eclampsia and GDM were independent risk factors for CVD (adjusted odds ratio [aOR] 2.59, 95% CI 2.12–3.17 and aOR 1.47, 95% CI 1.04–2.09, respectively). After stratifying by maternal BMI, the adjusted association of pre‐eclampsia with CVD did not differ notably between BMI groups: normal weight (aOR 2.65, 95% CI 1.90–3.69), overweight (aOR 2.67, 95% CI 1.52–4.68) and obesity (aOR 3.03, 95% CI 0.74–12.4). Similar findings were seen when stratifying on GDM/non‐GDM.ConclusionsPre‐eclampsia and GDM are independent risk factors for later CVD and having both during pregnancy is a major risk factor for later CVD. The association between pre‐eclampsia and CVD is not modified by BMI. Effective CVD preventive programs for high‐risk women are urgently needed in order to improve women's long‐term health.
Analysis of trifecta outcomes in a single center with robot‐assisted partial nephrectomy for T1b renal tumors
Authors: Masui Kimihiko , Matsuoka Takashi , Kono Jin , Sumiyoshi Takayuki , Kita Yuki , Sano Takeshi , Goto Takayuki , Akamatsu Shusuke , Kobayashi Takashi , Sawada Atsuro 
Published: March 2023

AbstractIntroductionThis study was performed to investigate the preoperative factors associated with difficulty achieving trifecta in robot‐assisted partial nephrectomy for clinical T1b renal cell carcinoma.MethodsAmong 187 patients who underwent robot‐assisted partial nephrectomy at our hospital from March 2012 to February 2022, we retrospectively examined 30 patients with unilateral single clinical T1b renal cell carcinoma with at least 6 months of postoperative follow‐up, excluding patients with hereditary disease. The following factors were examined in detail: patient‐related factors, perioperative factors, surgical techniques, tumor factors, and R.E.N.A.L. nephrometry scores. We examined the preoperative factors associated with difficulty achieving trifecta. A positive surgical margin was pathologically defined as the presence of tumor cells at the margin of the resected specimen or visually defined as intraoperative tumor incision or pseudocapsular damage.ResultsOf the 30 patients in this study, 12 achieved trifecta and 18 did not. The reasons for not achieving trifecta were a warm ischemia time of >25 min (66.7%), positive surgical margin (23.3%), and Clavien–Dindo grade ≥3 complications (13.3%) (with overlapping factors). No patients had a pathologically positive surgical margin. Visually positive surgical margins were confirmed by the surgical records and surgical videos. Achieving trifecta was challenging in the multivariate analysis when the “L” component of the R.E.N.A.L. nephrometry score was ≥2 points.ConclusionA preoperative “L” component of ≥2 points in the R.E.N.A.L. nephrometry score was associated with difficulty achieving trifecta.