bluuebunny/crossref_metadata_2025_split huggingface dataset:
Organizational Performance Evaluation of Flour Manufacturers: A Case Study of Hidiroğlu Flour Mills
Authors: HIDIROĞLU Duygu 
Published: July 2023

This study aims to examine how flour producers implement Organizational Theory Principles to their process and to define which organizational environmental and structural factors, culture and systems are appropriate for flour companies in order to improve companies’ success and entreprenuerial skills. For this purpose, this study analyzes a flour company and provides implications of the findings and limitations for the organization, its members, environment and stakeholders.
In this study, while examining on flour companies, a clear hierarchy in the organizations is observed in general. The flour producer HIDIROĞLU FLOUR MILLS taken as an example in the study gives importance to measurement, documentation and information systems management. The control mechanism is improved and the stability can be observed in every stages on the organizational structure. High standardization is a main feature of the company.
As a result of analyses of the flour producer taken as an example, the study come up with the idea: “it is crucial for flour producers to set standards and procedures, and have clear task definition in a plain hierarchy to achieve constant success”. On the other hand, the system boundary for this study is among Organizational Theory Principles whether Internal Process Model or Rational Goal Model is more suitable for flour producers and their entrepreneurial facilities.
Sobre a vivência do sentido no trabalho e nas organizações: contribuições da logoterapia e análise existencial
Authors: Andrade Rafael Rebouças , Ferreira Márcia Fernanda Moreno dos Santos , Gomes Rickardo Léo Ramos 
Published: July 2023

O ser humano costuma dedicar uma grande parte de sua vida ao trabalho. Se é alto o investimento de tempo, energia e dedicação, naturalmente, e, talvez, cada vez mais, muito também se espera da vida profissional na sociedade contemporânea. Dada a relevância que o trabalho tem na vida das pessoas na contemporaneidade, buscou-se desenvolver uma pesquisa de revisão narrativa, seguindo uma abordagem qualitativa, de modo a alcançar o objetivo geral deste artigo que seria o de conhecer as possíveis contribuições da Logoterapia e Análise Existencial ao contexto do trabalho e das organizações. A centralidade do conceito relativo ao sentido de vida para a Logoterapia e Análise Existencial contribui e convoca a se pensar a experiência humana a partir de suas ações, relações e formas de organização. Faz-se, portanto, necessário estabelecer espaços de reflexão sobre a relação entre sentido e trabalho para o homem e a mulher na contemporaneidade. Ao final a pesquisa revela que entre as principais implicações do pensamento Analítico Existencial aplicado ao sentido do trabalho e organizações, estaria a proposta de se estabelecer empresas mais humanas, requisito necessário para a vivência e potencialização de sentido no trabalho e nas organizações.
Exploring the effects of medical cannabis for chronic pain
Authors: Erridge Simon 
Published: July 2023

Exploring the effects of medical cannabis for chronic pain
Dr Simon Erridge of Sapphire Medical Clinics discusses the therapeutic effects of medical cannabis for chronic pain, affecting 15.5 million people in England and why more evidence is needed to support greater patient access. In November 2018, medical cannabis was rescheduled in the UK, allowing for the prescribing of unlicensed products manufactured from the cannabis plant for the first time since 1973. Chronic pain is now the most common condition for which medical cannabis is prescribed, according to the UK Medical Cannabis Registry. (1) Considering this increase in prescribing for eligible UK patients, it is important to understand the underlying science of how it affects the human body. Medical cannabis is the term given to a broad spectrum of medications that can be derived from the cannabis plant. The cannabis plant is thought to contain more than 540 active pharmaceutical ingredients; however, the most abundant compounds are cannabidiol (CBD) and (-)-trans-Δ9-tetrahydrocannabinol (THC). (2) The main mechanisms of action of these are via the body’s own cannabinoid system, which consists of molecules very similar to those found in the cannabis plant and receptors they bind to, causing downstream effects. One of the most important effects of this system is to regulate the firing of signals through nerves. (3,4) Some have therefore likened the endocannabinoid system to a dimmer switch for the nervous system.
NIJ puts science to work for justice system stakeholders
Authors: La Vigne Nancy 
Published: July 2023

NIJ puts science to work for justice system stakeholders
Nancy La Vigne PhD, Director of the National Institute of Justice, shares perspectives on how the Institute advances justice across the nation and beyond, strengthening the scientific tools and discoveries that support justice system stakeholders. The National Institute of Justice’s job is to generate the science that advances justice, mostly through research grants it awards to colleges, universities, and research institutes. As Director, La Vigne manages their efforts to ensure that NIJ, firstly, invests in research that addresses today’s problems while working toward a safer future and, secondly, disseminates that research widely. Nancy La Vigne discusses how new research must engage justice system stakeholders in clear, practical terms they understand, why there is a need for research through an equity lens, and how we can put science to work for justice requires clear communication of practical applications.
Improving AI/ML services for ophthalmology and medicine
Authors: Buckland Eric 
Published: July 2023

Improving AI/ML services for ophthalmology and medicine
Eric Buckland, PhD of Translational Imaging Innovations, delves into how we can achieve better transparency, traceability, and reproducibility in AI/ML for ophthalmology and medicine. Biomarkers are indispensable to finding cures and developing new therapies for degenerative eye diseases. Biomarkers are objectively measurable characteristics or indicators of normal biological processes, disease processes, or responses to therapeutic interventions. Biomarkers are essential to decision-making throughout drug development and patient care management. Dr. Buckland seeks to explain how biomarkers and clinical endpoints can transform ophthalmology, AI and ML for healthcare applications, and how biomarker development relies on transparency, traceability & reproducibility. Overall, Translational Imaging Innovations has committed to “delivering the most convenient and productive solutions for ophthalmic biomarker discovery and clinical endpoint validation”. TII aims to enable translational researchers to develop better diagnostics and better therapies with more predictable benefits – faster, cheaper, and less frustrating.
The question of being 'Roman': Examining ancient history more closely
Authors: Maier Felix K 
Published: July 2023

The question of being 'Roman': Examining ancient history more closely
Professor for Ancient History at the University of Zurich, provides an intriguing and instructive analysis of the question of being ‘Roman’ in his most recent ancient history focus. My history research project analyses the dynamics of different identities in the Roman Empire from around 50-150 AD. This project seeks to understand the often-paradoxical dynamics of different identities in a multicultural empire and to stimulate a discussion about hidden aspects of social interactions that we still need to understand correctly. Although the Roman era is entirely different to our times, some critical questions relate to today’s world, where social and political distinction mechanisms also lead to open or concealed conflicts.
The effect of soil degradation on human, animal and plant health
Authors: Sprunger Christine 
Published: July 2023

The effect of soil degradation on human, animal and plant health
Soil degradation is the biological, physical, chemical, and biological decline of soil quality or health. This phenomenon is problematic because it reduces the capacity of soils to support plant and animal life. Additionally, it reduces the ability of soils to regulate essential ecosystem services such as water regulation and nutrient cycling. Soil degradation has become a global issue and has come about largely due to land conversion from forests and grasslands to intensive agricultural practices. Land conversion depletes soil organic matter values, releasing large amounts of carbon dioxide into the atmosphere, contributing to global climate change and reducing soil fertility and soil health. Dr. Christine Sprunger, soil scientist and ecologist at W.K. Kellogg Biological Station (KBS) and the Department of Plant, Soil, and Microbial Sciences at Michigan State University, discusses the danger of soil degradation on human and animal life, and what we can do to mitigate it.
Insights into magnesium batteries using calorimetry
Authors: Ziebert Carlos 
Published: July 2023

Insights into magnesium batteries using calorimetry
Dr Carlos Ziebert, Leader of the Group Batteries – Calorimetry and Safety, KIT, explains how generated heat and self-discharge of magnesium batteries can be studied through calorimetry. In 2019, the KIT, the University of Ulm, the Center for Solar Energy and Hydrogen Research Baden- Württemberg, and the University of Giessen jointly launched the POLiS - Cluster of Excellence for Battery Research Post Lithium Storage, funded by €47 million over seven years. Such post-lithium batteries use more abundant and environmentally friendly materials, such as Sodium, Magnesium or Calcium, instead of Lithium, Nickel and Cobalt. The work in the group Batteries – Calorimetry and Safety at the Institute for Applied Materials – Applied Materials Physics (IAM-AWP) started with coin cells that were provided by the Helmholtz Institute Ulm (HIU) and the Institute of Nanotechnology (INT).
Urban living laboratories: Opportunities for modelling sustainability transitions
Authors: Dal-Poz Maria Ester , Francisco Erika Cristina , Paytan Adina Paytan , Wirth Timo von , Charlesworth Susanne , Fried Jana 
Published: July 2023

Urban living laboratories: Opportunities for modelling sustainability transitions
Here, a group of academics present Urban Living Laboratories to study sustainable food production systems, using systems dynamic modelling to analyse policy alternatives. Urban Living Laboratories (ULLs) have shown first promising signs of being valuable platforms for understanding transition phenomena. To address our time’s diverse grand societal challenges (like climate change and biodiversity loss), we must transition to truly sustainable systems, possibly the most significant shift facing modern civilisations. Such transitions involve coupled technological, social, economic and environmental shifts and demand transformative approaches with new forms of organisation and management.
Understanding thermolabile protecting groups for nucleic acid-based drugs
Authors: Beaucage Serge L 
Published: July 2023

Understanding thermolabile protecting groups for necleic acid-based drugs
Serge L. Beaucage investigates thermolabile protecting groups for the amine functions of purine and pyrimidine deoxyribonucleosides for the development and implementation of synthetic DNA sequences as nucleic acid-based drugs. The high demand for nucleic acid-based drugs, earmarked for treating human diseases, requires improved chemical methods for rapid and efficient chemical synthesis of synthetic DNA and/or RNA sequences with protecting groups before being processed and manufactured in sufficient quantity and purity for clinical indications. Given that the purity of synthetic DNA/RNA sequences is of the utmost importance for their intended purposes, sustained research efforts have been made.
Drug repositioning without the gene expression of disease cells treated with drugs
Authors: Taguchi Y-h 
Published: July 2023

Drug repositioning without the gene expression of disease cells treated with drugs
Y-h. Taguchi, Professor at the Department of Physics, Chuo University in Japan, provides comments on drug repositioning without the gene expression of disease cells treated with various drugs. Finding new drugs to treat diseases is always tricky. For example, although we have an effective mRNA vaccine for COVID-19, no effective drugs to treat COVID-19 have yet been identified. Since the difficulty is due to experiential evaluation, it is better to have a computer-oriented method. But how? We have one proposal for this at the Department of Physics, Chuo University in Japan. In our previous Open Access Government article, we introduce how to use gene expression (1) with which several drugs were treated for drug repositioning. The problem with the studies described in the last piece is that the strategy could be used only for diseases whose gene expression is retrieved. In the study described in the previous article, we analyzed gene expression profiles of cancer cell lines. Thus, the drug repositioning we could identify was only those toward cancers. This is a little bit problematic. If we would like to perform drug repositioning for other diseases, we need to prepare cell lines made from cells of target diseases. Since cancer cells are abnormal in some sense, it is not difficult to add immortality to cancer cell lines. Thus, we can easily maintain cancer cell lines in a Petri dish, but it is not the case for other cells. In addition to this, it is often challenging to collect cells from target diseases. It is time-consuming to treat cells of target diseases with various drugs.
Nutritional management of chronic kidney disease in pets
Authors: Creech Renea , Wilson Kim 
Published: July 2023

Nutritional management of chronic kidney disease in pets
Renea Creech and Kim Wilson outline the challenges of Chronic Kidney Disease in pets, the irreversible loss of kidney function, and how nutrition can help. Approximately one in three cats and one in ten dogs are likely to develop kidney disease in their lifetime. (1,2) Increased incidence of diagnosis occurs in older pets, particularly in cats. (3,4) A longevity study showed renal disorders were a major cause of death in cats over five years (5), and upwards of 80% aged over 15 years are affected by Chronic Kidney Disease (CKD) or other renal disorders. (3,4) Clinical signs include vomiting, decreased appetite, increased water intake, and total and lean body mass loss. Veterinarians often analyse urine and blood samples to determine biomarker levels such as serum creatinine and symmetric dimethylarginine (SDMA). The International Renal Interest Society provides veterinarians with guidance for diagnosing and managing kidney disease based on staging, with stage 1 representing early CKD and stage 4 severe CKD. (6)
Opioid use for chronic pain: Part 2
Authors: Buckley Norm , Busse Jason 
Published: July 2023

Opioid use for chronic pain: Part 2
Norm Buckley and Jason Busse from the Michael G. DeGroote Institute for Pain Research & Care in Canada probe the effectiveness of opioid use in Canada as a treatment for chronic noncancer pain. Current best estimates suggest that 12% of individuals with chronic noncancer pain will achieve meaningful pain relief with opioids; however, there is a disconnect between the evidence for effectiveness and the ubiquity of opioid prescribing in North America.
Renewfood manufacturing: Food production for a nourished, resilient nation
Authors: Wong Tuck Seng 
Published: July 2023

Renewfood manufacturing: Food production for a nourished, resilient nation
Dr Kang Lan Tee, Matthew Hutchinson, Joe Price and Professor Tuck Seng Wong from the University of Sheffield explain the importance of re-imagining food production to support people and the planet. Food transcends its basic role as a human necessity, encompassing a multifaceted significance in our lives. Beyond its fundamental function of providing nutrition and sustenance, food is a profound social instrument, it not only nourishes our bodies but also nourishes our relationships and interactions. Food production is undoubtedly vital to livelihoods everywhere. We gather around a shared meal with our family and friends, using this communal experience to foster and maintain deep interpersonal connections. In business, food is a catalyst for successful negotiations as we convene with clients or customers over a meal, forging bonds and laying the groundwork for prosperous partnerships.
Supporting ICT employment opportunities for women in Egypt
Authors: Assaad Ragui , Selwaness Irene 
Published: July 2023

Supporting ICT employment opportunities for women in Egypt
Ragui Assaad and Irene Selwaness examine the increase of women in ICT jobs in Egypt, as well as gender disparities and the efforts to promote ICT employment growth. With the increasing withdrawal of the public sector as a major employer in Egypt, the Egyptian labour market has become increasingly inhospitable for women. Female employment rates declined steadily from 19.5% in 2009 to 13.7% in 2021. Women’s employment has been falling in absolute terms at a rate of 1.1% per year from 2009 to 2021, while the female working-age population has been increasing at 2.5% annually. Information and communication technology (ICT) jobs are a major bright spot in this bleak landscape. According to a recent report on Egypt’s ICT jobs, ICT employment for women has been growing much faster than in other segments of the economy and much faster than for men (Selwaness, Assaad and El Sayed, 2023). The report defines ICT jobs as all jobs in ICT industries and jobs in ICT occupations in non-ICT sectors.
Emergent dimensionality: Exploring all possible (and unobservable) extra dimensions
Authors: Łukaszyk Szymon 
Published: July 2023

Emergent dimensionality: Exploring all possible (and unobservable) extra dimensions
Emergent dimensionality (ED) is the idea that reality may not exist as an observer-independent 3-dimensional space. Instead, it may be generated for each observer based on an omnidimensional graph that contains all possible (and unobservable) extra dimensions. In other words, each observer perceives reality as 3-dimensional, but this reality emerges from a higher-dimensional structure. TED is related to the perception of reality because it suggests that what we perceive as a 3-dimensional space is not the full picture of reality.
Solutions for healthy ageing: how technology can make a difference
Authors: Mihailidis Alex 
Published: July 2023

Solutions for healthy ageing: how technology can make a difference
How do we help older adults maintain their independence and quality of life with healthy ageing? Professor Alex Mihailidis, Scientific Director and CEO of AGE-WELL Network of Centres of Excellence argues that improving wellbeing in older people should come from innovative technology. Research finds that technological advancements can help older people maintain relationships with family and friends, reduce social isolation, pursue hobbies, manage all aspects of health, and stay active and in their own homes as they age. To further this research, AGE-WELL brings together researchers, older adults, caregivers, partner organizations (industry, government, community) and future leaders to accelerate the delivery of technology-based solutions that increase safety and security, support independent living and enhance social participation. While technology can never replace the human touch, it is an essential tool in the toolbox to support healthy ageing, and for this to improve for the older generation, technologies must become accessible, affordable and available to all.
Knee pain and osteoarthritis (Knee OA) treatment research
Authors: Lyu Shaw-Ruey 
Published: July 2023

Knee pain and osteoarthritis (Knee OA) treatment research
Professor Shaw-Ruey Lyu from the School of Medicine, Tzu-Chi University, discusses Knee Pain and Osteoarthritis (Knee OA) Treatment Research, in particular Knee Health Promotion Option (KHPO). Starting from 2002, I conducted a series of studies(1-3,5,6,8,9) to investigate medial abrasion phenomenon (MAP) as a cause of knee OA. I found a high correlation between medial plica-related MAP and knee OA. MAP would elicit lifelong interplay between a pathologic medial plica and the facing medial femoral condyle, and therefore plays a role in the pathogenesis of knee OA both physically and chemically.(10,11,13) Consequently, I have developed the procedures of arthroscopic medial release (AMR)(4) and the concept of arthroscopic cartilage regeneration facilitating procedure (ACRFP)(7,15) for the treatment of knee OA.
Inspiring STEM education focused on solutions
Authors: Songer Nancy Butler 
Published: July 2023

Inspiring STEM education focused on solutions
Nancy Butler Songer, from the University of Utah, makes a call for collective action to create a new curriculum focused on the design of solutions. June 5, 2023, marked The United Nations Environment Programme’s (UNEP) fiftieth anniversary of World Environment Day, the largest global platform for environmental public outreach. Hosted by Côte D’Ivoire, this year’s celebration emphasized a need for collective action and policy to realize known solutions, such as the sustainable design of products and materials to reduce how much plastic waste flows into aquatic ecosystems. World Environment Day helps us to recognize that to address many current environmental, educational, health, and economic challenges that have foundations in Science, Technology, Engineering, and Mathematics (STEM) disciplines, we cannot rely on individuals or even experts within one area of science, technology, engineering, mathematics, or education. We must innovate with, study, and empower students, teachers, community members, and university and industry partners toward collective action.
The next frontier in anti-cancer drugs
Authors: Berdis Anthony J 
Published: July 2023

The next frontier in anti-cancer drugs
Dr Anthony J. Berdis, Case Comprehensive Cancer Center discusses the future of cancer treatments and anti-cancer drugs. Being diagnosed with cancer is a horrifying experience for patients and their loved ones. What comes next – discussing treatment strategies – can also strike terror due to the numerous uncertainties associated with the process, procedures that will be used, and possible outcomes. Most cancers are treated using combination therapy in which surgery and/or radiation is first used to remove and eliminate as much cancerous material as possible. This is then followed by several rounds of chemotherapy, an anti-cancer drug designed to eradicate any remaining cancer cells. The goal of this strategy is to achieve remission or at least delay the cancer from returning for as long as possible.
What is the importance of friendship and mental health in pandemics?
Authors: Ryan Terence 
Published: July 2023

What is the importance of friendship and mental health in pandemics?
Terence j Ryan, from the University of Oxford, explores the importance of friendship and mental health in relation to pandemics and immunity. In the last three years, there has been a significant rise in impaired mental health. Many have asked whether this rise is due to the COVID-19 infection itself or if it is a consequence of how officials managed the pandemic. A close colleague of mine, together running NHS and academic departments without a cross word for fifty years, had suffered from mild dementia and COVID in a care home and, as a result, was isolated from seeing his family and friends for over a year, except through a window. This was during the same period that I was a trustee of Actasia, working to prevent the cruelty and caging of wild animals. It is clear from conducting this work, that such cruelty impairs immunity and resistance and thus increases susceptibility to infection.