bluuebunny/crossref_metadata_2025_split huggingface dataset:
Decolonising the design curriculum: making “sustainability” accessible, understandable and practicable to second-year undergraduate architecture students
Authors: Datey Aparna 
Published: February 2023

PurposeThis paper describes the curriculum design of an architectural studio course aimed at making concepts of sustainability accessible, understandable and practicable to second-year undergraduate students. Architectural education and design pedagogy is shaped and interrogated in the Global North or Western Europe and North America and influences various pedagogical approaches in the Global South. By including exemplars, voices and practices from global, historical, vernacular and contemporary contexts, understanding of sustainability is enriched.Design/methodology/approachThe approach to course design included decolonising the curriculum and making it relevant for globally diverse future professionals. The studio theme of “memory and history” was framed as responsiveness to context and experiencing the site. Students were required to define place, and articulate form and space with sensitivity towards social, cultural, environmental and ecological aspects. The lectures, exercises and interactive activities emphasised design process, in-progress work, and experimentation through sketching, diagramming, drawing, and making study models which scaffolded student learning under the guidance of tutors.FindingsThe findings show that to make the process of learning to design in an environmentally responsive manner explicit for students, approaches to curriculum design must have a global and inclusive curriculum, engage students in experiential learning through doing/making to develop critical thinking skills, encourage students to synthesise and transfer learning to and from other settings and contexts, and interpret knowledge-power relationships and co-construction processes embedded in studio-based teaching and learning.Originality/valueThe original contribution of the course is that it creates an inclusive, experimental and decolonised space for co-construction of knowledge about designing sustainable environments.
The positioning of CEOs as advocates and activists for societal change: reflecting media, receptive and strategic cornerstones
Authors: Bojanic Vanja 
Published: February 2023

PurposeThis paper aims to take stock of current knowledge on chief executive officers (CEOs) speaking out on societal issues and to position the phenomenon with and against the relevant literature on CEO communication. Ultimately, the paper seeks to arrive at a better conceptual understanding of CEO advocates and activists from a communication science perspective.Design/methodology/approachThis paper is conceptual and considers findings from the literature on personalization, reputation, issues and topic management.FindingsThe paper reflects media, receptive and strategic implications for CEO advocates and activists and derives four workable propositions. It lays the foundation for treating CEO advocacy and activism as a form of strategic topic management that harnesses personalization to address a new set of stakeholder demands.Practical implicationsThe insights gained from this paper may help researchers and practitioners understand when CEOs should speak up, what to communicate and how. The human element behind this kind of communication echoes new expectations, demands and values from stakeholders, shareholders and society at large.Social implicationsUnderstanding the specific interdependencies between personalization, reputation, issues and topic management underlying CEO advocacy and activism can help to improve a CEO's relationship with stakeholders and guide the public discourse to actively bring about positive societal change.Originality/valueThe paper fills a gap by providing an understanding of advocate and activist CEOs from a communication science perspective. The insights from this paper can be used as a starting point for further research on this subject.
Does crowdsourcing necessarily lead to brand engagement? The role of crowdsourcing cues and relationship norms on customer-brand relationships
Authors: Herter Márcia Maurer , Shuqair Saleh , Pinto Diego Costa , Mattila Anna S. , Zandonai Pontin Paola 
Published: February 2023

Purpose
This paper aims to examine how the relationship norms established between customers and brands influence customer perceptions of crowdsourcing (vs firm-generated) cues.

Design/methodology/approach
Four studies (N = 851) examine the moderating role of relationship norms on product labeling cues (crowdsourcing vs firm-generated) effects on brand engagement, and the underlying mechanism of self-brand connection.

Findings
The findings suggest that crowdsourcing (vs firm-generated) cues lead to higher brand engagement (Studies 1A–1B), mediated by self-brand connection (Studies 2–3). In addition, relationship norms moderate the effects (Study 3), such that under exchange brand relationships crowdsourcing (vs firm-generated) cues yield higher brand engagement, whereas communal brand relationships reverse such effects.

Practical implications
The findings provide valuable managerial implications by highlighting the importance of using relationship norms as diagnostic cues to successfully implement crowdsourcing initiatives.

Originality/value
This research adds to the customer-brand relationship literature by revealing an accessibility-diagnosticity perspective of consumers’ reactions to crowdsourcing (vs firm-generated) cues.
Gauging the impact of negative media publicity on career decisions: exploring police recruit motivations during a recruitment crisis
Authors: Wojslawowicz Ashleigh N. , Doan Robert J. , Fish Jacqueline T. , Spencer James A. 
Published: February 2023

PurposeThe purpose of the study was to provide greater understanding of the policing recruitment crisis by exploring if and how recruit decisions to become an officer were influenced by negative media publicity, As police recruits are a viable source for recruitment data.Design/methodology/approachBasic law enforcement (BLE) candidates attending a southeastern state police academy were surveyed (N = 395) on perceptions of danger and current officer motivation (i.e. the “Ferguson Effect”), as well as motivation variables for entering police work.FindingsResults found little to no influence of negative media on decisions and career motivations, despite respondents acknowledging agreement to Ferguson Effect variables.Research limitations/implicationsFindings suggest negative media publicity was not a contributing factor for the studied sample; however, further recruit-based research is advocated to understand contemporary law enforcement recruitment strategies.Practical implicationsAs police organizations continue to face difficulty in hiring and retaining qualified candidates, understanding the next generation of officers has never been more crucial. This study provides a model for police organizations to incorporate recruit data into evidence-based procedures.Social implicationsAs findings suggest the acknowledgment of Ferguson Effect variables to be present, social implications include the possible long-term impacts of these perceptions on officer career progression and the police culture.Originality/valueAt the time of this study, no known work has examined police recruit motivations against the backdrop of negative media. This study is the first known research to explore the potential impact of Ferguson Effect variables on police academy recruits in the United States.
Discourse and the creation of French green bond legitimacy
Authors: Riaz Umair , Al Mahameed Muhammad , Gentemann Lisa , Dunne Theresa 
Published: February 2023

Purpose
This study aims to explore how organisations use institutional language in Green Bond reports to explain and justify their activities using language that describes and reflects narratives while simultaneously constructing and shaping ideology. The paper mobilises Wodak and Meyer’s critical discourse analysis (CDA) to examine reports and related documentation relating to Green Bonds issued in France.

Design/methodology/approach
The study uses three legitimating discourses: technocratic, environmental and social and business performance to develop a linguistic perspective that permits contributions to existing knowledge in the area.

Findings
The analysis attempts to identify the discursive strategies used to legitimise Green Bond issuance via claims linked to environmental management improvements and business activities’ social impact.

Originality/value
The study contributes to the critical literature on organisational legitimation and responsibility, investigations of Green Bond narratives and an understanding of broader environmental reporting in the financial sector.
How crop insurance influences agrochemical input use: Evidence from cotton farmers in China
Authors: Mao Hui , Chen Shaojian , Ying RuiYao , Fu Yong 
Published: February 2023

AbstractCrop insurance is critical in risk management in global agricultural production (e.g. by helping stabilise farmers' incomes in the long term and reducing risk‐bearing costs). In this paper, using field survey data on cotton farmers in Xinjiang, China, we examine the influence of crop insurance on farmers' behaviours regarding agrochemical inputs and aim to investigate the synergy between crop insurance and reductions in fertiliser and pesticide usage. We find evidence that crop insurance significantly negatively affects farmers' use of fertilisers and pesticides, as well as significantly positively affects their adoption of green agricultural technologies (GAT) that can replace or complement traditional fertilisers and pesticides. Moreover, our results reveal that compared with small‐scale farmers, crop insurance has a stronger effect on large‐scale farmers' use of agrochemicals. Finally, when the insured amount is higher or the relative deductible is lower, farmers are more likely to reduce fertiliser and pesticide usage and adopt GAT. Overall, this paper scientifically identifies crop insurance can improve farmers' agrochemical input behaviour, by reducing farmers' use of traditional agrochemical inputs and increasing their adoption of GAT, which is of great significance for ensuring the safety of the agricultural ecological environment.
On the double social life of failure
Authors: Reeves Madeleine 
Published: February 2023

AbstractWhat might it mean to follow failure ‘out into the world’ (Alexander, introduction to this volume) in a way that is attentive both to its contingent and diffuse effects, and to the work involved in making it socially legible? This essay follows a moment of social breakdown, its reverberations in social life, and the forms of diagnosis it elicited as a way of exploring the double social life of failure. Focusing on the aftermath of Kyrgyzstan's 2010 ‘Osh events’ (Oshskie sobytiia) as they took hold in a multi‐tenant and ethnically mixed dormitory apartment for migrant workers in Moscow, I follow failure forwards, exploring how a period of intercommunal violence reverberated in a context of protracted work migration, legal non‐recognition, and the digital circulation of blame. I also track it backwards, attending to my interlocutors’ practices of diagnosis and excavation. Among Kyrgyz and Uzbeks in Moscow, the Osh events figured as indexical of different kinds of failure – whether of protection, recognition, or proper state care. I take vernacular diagnoses of bardak – normative breakdown – as an ethnographic entry point for thinking about the spatial and temporal afterlives of violence, their articulation in an age of digital mediation, and the ethics of naming and diagnosing failure.
A review of the structure, function, and application of plant‐based protein–phenolic conjugates and complexes
Authors: Yan Xianghui , Zeng Zheling , McClements David Julian , Gong Xiaofeng , Yu Ping , Xia Jiaheng , Gong Deming 
Published: February 2023

AbstractInteractions between plant‐based proteins (PP) and phenolic compounds (PC) occur naturally in many food products. Recently, special attention has been paid to the fabrication of PP–PC conjugates or complexes in model systems with a focus on their effects on their structure, functionality, and health benefits. Conjugates are held together by covalent bonds, whereas complexes are held together by noncovalent ones. This review highlights the nature of protein–phenolic interactions involving PP. The interactions of these PC with the PP in model systems are discussed, as well as their impact on the structural, functional, and health‐promoting properties of PP. The PP in conjugates and complexes tend to be more unfolded than in their native state, which often improves their functional attributes. PP–PC conjugates and complexes often exhibit improved in vitro digestibility, antioxidant activity, and potential allergy‐reducing activities. Consequently, they may be used as antioxidant emulsifiers, edible film additives, nanoparticles, and hydrogels in the food industry. However, studies focusing on the application of PP–PC conjugates and complexes in real foods are still scarce. Further research is therefore required to determine the structure–function relationships of PP–PC conjugates and complexes that may influence their application as functional ingredients in the food industry.
Repeated co‐exposure to aflatoxin B1and aspartame disrupts the central nervous system homeostasis: Behavioral, biochemical, and molecular insights
Authors: Souto Naieli Schiefelbein , Dassi Micheli , Braga Ana Cláudia Monteiro , Rosa Érica Vanessa Furlan , Fighera Michele Rechia , Royes Luiz Fernando Freire , Oliveira Mauro Schneider , Sari Marcel Henrique Marcondes , Furian Ana Flávia 
Published: February 2023

AbstractSeveral studies demonstrated the toxicity of aspartame (ASP) and aflatoxin B1(AFB1) in preclinical models. Although the majority of these reports assessed the toxic effects of each substance separately, their concomitant exposure and hazardous consequences are scarce. Importantly, the deleterious effects at the central nervous system caused by ASP and AFB1co‐exposure are rarely addressed. We evaluated if concomitant exposure to AFB1and ASP would cause behavioral impairment and alteration in oxidative status of the brain in male rats. Animals received once a day for 14 days AFB1(250 µg/kg, intragastric gavage [i.g.]), ASP (75 mg/kg, i.g.), or both substances (association). On day 14, they were subjected to behavioral evaluation, and biochemical and molecular parameters of oxidative status were measured in the cerebral cortex and hippocampus. In the open field test, AFB1and combination treatments modified the motor, exploratory, and grooming behavior. In the splash test, all treatments caused a reduction in grooming time compared to the control group. An increase in thiobarbituric acid‐reactive substances content induced by AFB1and combination treatments was observed. The antioxidant defenses (vitamin C, nonprotein sulfhydryl, and ferric reducing antioxidant power) were impaired in all groups compared to control. Regarding molecular evaluation, mitochondrial superoxide dismutase‐2 immunoreactivity decreased after AFB1or ASP exposition in the hippocampus. Thus, co‐exposure to ASP and AFB1was potentially more toxic because it aggravated behavioral impairments and oxidative status disbalance in comparison to the groups that received only ASP or AFB1. Therefore, our data suggest that those substances caused a disruption in brain homeostasis.
Sex differences in prognostic role of fasting glucose, Oral glucose tolerance, and HbA1c in diabetic cardiovascular disease
Authors: Yoshida Yilin , Chen Zhipeng , Baudier Robin L. , Krousel‐Wood Marie , Anderson Amanda H. , Fonseca Vivian A. , Mauvais‐Jarvis Franck 
Published: February 2023

Highlights
Fasting glucose‐defined prediabetes and undiagnosed diabetes based on the American Diabetes Association criteria were associated with a greater risk of coronary heart disease, stroke, and composite atherosclerotic cardiovascular disease in women. In contrast, oral glucose tolerance‐defined prediabetes and undiagnosed diabetes were associated with a greater risk of all cardiovascular outcomes in men.
Intermediate A1c was associated with a more pronounced effect on the risk of coronary heart disease and stroke in women, whereas the above diagnostic level of A1c was associated with a higher magnitude of coronary heart risk in undiagnosed men but a higher magnitude of stroke risk in undiagnosed women.
Long non‐coding RNA telomerase RNA elements improve glucocorticoid‐induced osteoporosis by EZH2 to regulate DKK1
Authors: Hu He , Guo Xiaodong , Mu Tingting , Song Huifang 
Published: February 2023

AbstractBackgroundGlucocorticoid‐induced osteoporosis is the most common secondary cause of osteoporosis, which increases the risk of fracture. Long non‐coding RNA telomerase RNA elements (TERC) has been proven to be closely related to osteoporosis. However, the role of TERC in glucocorticoid‐induced osteoporosis and its underlying molecular mechanism remains unclear.MethodsThe in vitro model of osteoporosis was established after bone marrow mesenchymal stem cells (BMSCs) were exposed to dexamethasone (DEX). The cell viability, alkaline phosphatase (ALP) activity and mineralized nodules of BMSCs were evaluated. The messenger RNA and protein levels were detected by quantitative real‐time polymerase chain reaction and Western blot. The interaction between TERC, enhancer of zeste homolog 2 (EZH2) and dickkopf‐1 (DKK1) was confirmed by chromatin immunoprecipitation and RNA immunoprecipitation assays.ResultsBone marrow mesenchymal stem cells were isolated, identified and induced osteogenic differentiation. The findings showed that the levels of osteogenic marker genes, including ALP, Runt‐related transcription factor 2 (RUNX2) and osteocalcin (OCN) in BMSCs were increased dependent on the osteogenic induction time. Similarly, TERC was significantly increased, but DKK1 was significantly decreased during BMSC osteogenic differentiation. Functional research showed that TERC overexpression promoted cell viability, ALP activity and mineralized nodules of BMSCs and increased the levels of osteogenic differentiation‐related genes (ALP, RUNX2 and OCN), and TERC overexpression increased EZH2 protein level. Moreover, the decrease of cell viability, ALP activity and mineralized nodules induced by DEX was reversed by TERC overexpression. Furthermore, TERC inhibited DKK1 expression by promoting the histone modification of DKK1, and TERC overexpression alleviated DEX suppressed osteogenic differentiation of BMSCs by interaction with EZH2 to regulate DKK1.ConclusionOur findings illustrated that TERC overexpression alleviated DEX‐induced osteoporosis by recruiting EZH2 to regulate DKK1. Our research provided a novel direction for the treatment of glucocorticoid‐induced osteoporosis.
Comparison of neoadjuvant nab‐paclitaxel plus immunotherapy versus paclitaxel plus immunotherapy for esophageal squamous cell carcinoma
Authors: Yang Yafan , Li Haomiao , Chen Xiankai , Qin Jianjun , Li Yong , Shen Yaxing , Zhang Ruixiang , Kang Xiaozheng , Wang Zhen , Zheng Qingfeng , Luo Peng , Li Yin , He Jie 
Published: February 2023

AbstractBackgroundThis study aimed to compare the feasibility of nab‐paclitaxel plus platinum‐based chemotherapy (nabTP) versus paclitaxel plus platinum‐based chemotherapy (TP) with immune checkpoint inhibitors (ICIs) as a neoadjuvant modality for locally resectable esophageal squamous cell carcinoma (ESCC).MethodsBetween April 2019 and March 2022, we identified ESCC patients who received neoadjuvant immunotherapy with both nabTP (n = 213) and TP (n = 98) at our institution and Henan Cancer Hospital. The patients in the ICIs‐nabTP and ICIs‐TP groups were pair‐matched (1:1) for tumor location, sex, smoking, drinking, clinical T and N stage. The primary endpoint was the hazard of 30‐day major postoperative complications. Second, logistic models were applied to estimate the risk factors for pathological complete response (pCR) rate.ResultsAll patients underwent esophagectomy with R0 resection. A statistically significant increase in the risk of developing major pulmonary (odds ratio [OR], 1.182; 95% confidence interval [CI]: 0.530–2.635; p = 0.683), anastomotic (OR, 1.881; 95% CI: 0.607–5.830; p = 0.267), cardiac (OR, 1.000; 95% CI: 0.426–2.349; p = 1.000) complications after neoadjuvant immunotherapy plus nabTP was not observed. The median interval to surgery was 39 days in the ICIs‐nabTP group versus 44 days in the ICIs‐TP group (p = 0.119). There was no 30‐day mortality in each group. However, there was a slight difference in the 30‐day readmission rate (p = 0.043) and the incidence of hydropneumothorax (p = 0.027) between the two groups. The pCR rates of the ICIs‐nabTP and ICIs‐TP group were 36.7 and 21.4%, respectively (p = 0.018).ConclusionsIt appears to be feasible to add immunotherapy to nabTP regimen for locally advanced ESCC. Compared with TP, nabTP plus ICIs can achieve a better pCR rate in ESCC.
Safety of performing classical versus low transverse caesarean sections in extremely preterm and very preterm births: Maternal and neonatal complications
Authors: Lau Max C. , Tanaka Keisuke , Amoako Akwasi , Rudra Thangeswaran 
Published: February 2023

AimsImproved survivability of extremely preterm infants has led to increased rates of caesarean sections. Short‐term maternal and neonatal risks of classical caesarean sections (CCS) in the context of extreme prematurity remain unclear. The aim was to examine maternal and neonatal complications associated with CCSs versus low transverse caesarean sections (LTCS) at extremely preterm (23 0/7–27 6/7 weeks) and very preterm gestational ages (28 0/7–31 6/7 weeks).MethodsA retrospective cohort study was conducted at Royal Brisbane and Womens Hospital, Queensland, Australia between 2016 and 2020. Maternal and neonatal outcomes were examined using univariate and multivariate statistical analysis.ResultsCCSs (extremely preterm: n = 93; very preterm: n = 83) were associated with higher estimated blood loss than LTCS (extremely preterm: n = 70; very preterm: n = 287) in very preterm births (CCS: 638 ± 410 mL; LTCS: 556 ± 397 mL; P = 0.01). There was no significant difference in composite maternal outcomes between CCS and LTCS for extremely preterm (adjusted odds ratio (aOR): 1.11; 95% confidence interval (CI): 0.58–2.12; P = 0.75) or very preterm births (aOR: 1.08; 95% CI: 0.63–1.94; P = 0.79) after accounting for multiple pregnancy, placenta accreta and non‐cephalic fetal presentations. Although CCSs were associated with lower Apgar scores at 1 min post‐birth than LTCSs at very preterm gestational ages (CCS: 5.58 ± 2.10; LTCS: 6.25 ± 2.14; P = 0.02), there was no statistical difference in the rates of intraoperative neonatal injuries or composite outcomes when corrected for low birth weight.ConclusionShort‐term maternal and neonatal outcomes do not significantly differ between CCS and LTCS for extremely preterm or very preterm births.