bluuebunny/crossref_metadata_2025_split huggingface dataset:
RETRACTED: Acute burns during the COVID‐19 pandemic: A one‐year retrospective study of 611 patients at a referral burn centre in northern Iran
Authors: Mobayen Mohammadreza , Torabi Hossein , Bagheri Toolaroud Parissa , Tolouei Mohammad , Dehnadi Moghadam Anoush , Saadatmand Mohammad , EslamiKenarsari Habib , Feizkhah Alireza , Ghazanfari Mohammad Javad , Osuji Joseph , Ghorbani Vajargah Pooyan , Karkhah Samad 
Published: April 2023

AbstractPatients with acute burns are more vulnerable to COVID‐19 because of physiologically weak immune systems. This study aimed to assess and compare individual characteristics, clinical features, and clinical outcomes of acute burn among COVID‐19 and non‐COVID‐19 patients. A retrospective study, with data collected from 611 acute burn patients with or without a COVID‐19 diagnosis referred to a burn centre in Iran. Data were collected from April 2020 to 2021. The mean age of acute burns patients with COVID‐19 was higher compared with acute burns patients with non‐COVID‐19 (47.82 vs. 32.59 years, P < .001). Acute burns occurred more frequently in COVID‐19 patients with comorbidities compared with non‐COVID‐19 patients (48.72% vs. 26.92%, P = .003). 58.97% of COVID‐19 patients and 55.42% of non‐COVID‐19 patients had grade II & III and II burns, respectively (P < .001). The mean total body surface area of the burn was higher in COVID‐19 patients compared with non‐COVID‐19 patients (32.69% vs. 16.22%, P < .001). Hospitalisation in the intensive care unit (ICU) was higher in COVID‐19 patients than in non‐COVID‐19 patients (76.92% vs. 15.73%, P < .001). Length of stay in hospital and ICU, the cost of hospitalisation, and waiting time for the operating room was higher in COVID‐19 patients compared with non‐COVID‐19 patients (15.30 vs. 3.88 days, P < .001; 9.61 vs. 0.75 days, P < .001; 30 430 628.717 vs. 10 219 192.44 rials, P = .011; 0.84 vs. 0.24 min, P < .001, respectively). Intubation and mortality in‐hospital were higher in COVID‐19 patients compared with non‐COVID‐19 patients (41.02% vs. 6.99%, P < .001; 35.90% vs. 6.12%, P < .001, respectively). Therefore, it is recommended that health managers and policymakers develop a care plan to provide high‐quality care to acute burns patients with COVID‐19, especially in low‐income countries.
Selective detection of urease‐producing bacteria on the genital skin surface in patients with incontinence‐associated dermatitis
Authors: Kohta Masushi , Koyanagi Hiroe , Inagaki Yoshinobu , Nishikawa Keiji , Kobayashi Nanako , Tamura Shigeru , Ishikawa Miyuki , Banno Yumi , Takekoshi Kanako , Mano Keiko , Sugama Junko 
Published: April 2023

AbstractWe aimed to investigate the association between the presence of cutaneous urease‐producing bacteria and the development of incontinence‐associated dermatitis (IAD) using an original urea agar medium as a step toward developing advanced preventive measures. In previous clinical assessments, we developed an original urea agar medium to detect urease‐producing bacteria via the medium's colour changes. In a cross‐sectional study, specimens were collected via the swabbing technique at genital skin sites in 52 stroke patients hospitalised in a university hospital. The primary objective was to compare the presence of urease‐producing bacteria between the IAD and no‐IAD groups. Determining the bacterial count was the secondary objective. The prevalence of IAD was 48%. A significantly higher detection rate of urease‐producing bacteria was observed in the IAD group than in the no‐IAD group (P = .002) despite the total number of bacteria being equivalent between them. In conclusion, we discovered that there was a significant association between the presence of urease‐producing bacteria and IAD development in hospitalised stroke patients.
Forced surgical extrusion using an axial tooth extraction system as a practicable technique for preserving severely destroyed teeth? ‐ Clinical outcomes up to 4.8 years
Authors: Graf Tobias , Stimmelmayr Michael , Gutmann Pauline , Güth Jan‐Frederik , Krennmair Gerald , Edelhoff Daniel , Schubert Oliver 
Published: April 2023

AbstractObjectiveSeveral extrusion techniques have been described to restore teeth with insufficient coronal tooth structure and to avoid their extraction. Still, there is little evidence for a treatment concept combining surgical extrusion using an atraumatic axial extraction system.Materials and MethodsA total of nine patients, each with an iso‐ or subgingival fractured tooth, were retrospectively examined. Treatment of the damaged tooth comprised an atraumatic forced surgical extrusion performed with an axial tooth extraction system and a more coronal positioning within the socket. The teeth were initially splinted and subsequently restored. The follow‐up period was up to 57.1 months and averaged 36.5 (SD: ±13.5) months.ResultsAll nine teeth were still in situ, without signs of inflammation. During the period of the provisional restoration, six prosthetic complications occurred, which were resolved with little effort, whereas, success rate for the definitive restoration was 100%. No biological complications were observed concerning the root apex or soft tissue. The radiographically measured mean extrusion distance was 3.4 (SD: ±1.0) mm, so that a sufficient prosthetic ferrule could be reestablished.ConclusionsSurgical extrusions using an axial tooth extraction system demonstrate low biological and prosthetic complications rates over observation time.Clinical SignificanceThe presented extrusion approach preserves soft and hard tissue and is an efficient treatment option for severely destroyed teeth. Saving hopeless teeth by this relatively predictable and feasible procedure has hardly any disadvantages for patients, and in case of failure, an implant or fixed partial denture are still an option.
Insights from catch composition and historical records of elasmobranchs in the Malvan fishery on the central west coast of India
Authors: Kottillil Shruthi , Gupta Trisha , Manoharakrishnan Muralidharan , Rao Chetan , Shanker Kartik 
Published: April 2023

AbstractAlthough elasmobranchs (sharks and rays) are highly threatened by fisheries, there are few studies that examine gear and fishery effects on catch composition and abundance across India, one of the top elasmobranch fishing nations globally. We assessed elasmobranch diversity, abundance, catch rates and fishery characteristics using landing surveys in Malvan on the central‐western coast of India, a major multi‐gear, multi‐species fishing centre, over three sampling periods from February 2018 to March 2020. We sampled 3145 fishing trips and recorded 27 elasmobranch species, of which nearly half are categorised as “Threatened” by the IUCN. In addition, we documented historical records by compiling information from identification guides, research papers, articles and reports. During the study period, the catch was dominated by small‐sized coastal species like the spadenose shark (Scoliodon laticaudus) and the scaly whipray (Brevitrygon walga). Trawlers accounted for 64.9% of the catch, highest by number, and captured smaller‐sized individuals. Nonetheless, artisanal and gillnet fisheries had higher catch per unit effort (CPUE) for rays (5.1 ± 1.0) and sharks (10 ± 1.0), respectively, and captured significantly larger‐sized individuals. Through generalised linear models, we found seasonal, gear and fishery effects on the abundance and size of commonly caught species. The presence of neonates and gravid females of multiple species also suggests nursery grounds in this region. Historically, 141 species have been recorded in this region, and a comparison with current catch suggests a shift in elasmobranch community structure and potential mesopredator release. This study emphasises the importance of gear and species‐specific research for conservation planning at the local level and suggests the need for management strategies with fisher cooperation.
NIGT1 represses plant growth and mitigates phosphate starvation signaling to balance the growth response tradeoff in rice
Authors: Zhang Yuxin , Zhang Qianqian , Guo Meina , Wang Xueqing , Li Tianjie , Wu Qingyu , Li Lihui , Yi Keke , Ruan Wenyuan 
Published: April 2023

AbstractInorganic phosphate (Pi) availability is an important factor which affects the growth and yield of crops, thus an appropriate and effective response to Pi fluctuation is critical. However, how crops orchestrate Pi signaling and growth under Pi starvation conditions to optimize the growth defense tradeoff remains unclear. Here we show that a Pi starvation‐induced transcription factor NIGT1 (NITRATE‐INDUCIBLE GARP‐TYPE TRANSCRIPTIONAL REPRESSOR 1) controls plant growth and prevents a hyper‐response to Pi starvation by directly repressing the expression of growth‐related and Pi‐signaling genes to achieve a balance between growth and response under a varying Pi environment. NIGT1 directly binds to the promoters of Pi starvation signaling marker genes, like IPS1, miR827, and SPX2, under Pi‐deficient conditions to mitigate the Pi‐starvation responsive (PSR). It also directly represses the expression of vacuolar Pi efflux transporter genes VPE1/2 to regulate plant Pi homeostasis. We further demonstrate that NIGT1 constrains shoot growth by repressing the expression of growth‐related regulatory genes, including brassinolide signal transduction master regulator BZR1, cell division regulator CYCB1;1, and DNA replication regulator PSF3. Our findings reveal the function of NIGT1 in orchestrating plant growth and Pi starvation signaling, and also provide evidence that NIGT1 acts as a safeguard to avoid hyper‐response during Pi starvation stress in rice.
Golgi‐localized MORN1 promotes lipid droplet abundance and enhances tolerance to multiple stresses in Arabidopsis
Authors: Li Zhan , Gao Yue , Yan Jiapei , Wang Shuai , Wang Shu , Liu Yuanyuan , Wang Shaokui , Hua Jian 
Published: April 2023

AbstractLipid droplet (LD) in vegetative tissues has recently been implicated in environmental responses in plants, but its regulation and its function in stress tolerance are not well understood. Here, we identified a Membrane Occupation and Recognition Nexus 1 (MORN1) gene as a contributor to natural variations of stress tolerance through genome‐wide association study in Arabidopsis thaliana. Characterization of its loss‐of‐function mutant and natural variants revealed that the MORN1 gene is a positive regulator of plant growth, disease resistance, cold tolerance, and heat tolerance. The MORN1 protein is associated with the Golgi and is also partly associated with LD. Protein truncations that disrupt these associations abolished the biological function of the MORN1 protein. Furthermore, the MORN1 gene is a positive regulator of LD abundance, and its role in LD number regulation and stress tolerance is highly linked. Therefore, this study identifies MORN1 as a positive regulator of LD abundance and a contributor to natural variations of stress tolerance. It implicates a potential involvement of Golgi in LD biogenesis and strongly suggests a contribution of LD to diverse processes of plant growth and stress responses.
Ferroptosis and central nervous system demyelinating diseases
Authors: Qin Danqing , Li Dong , Wang Chunjuan , Guo Shougang 
Published: April 2023

AbstractFerroptosis is a newly discovered programmed cell death caused by intracellular iron excess and glutathione (GSH) system imbalance, resulting in fatal lipid peroxidation. It is different from necrosis, apoptosis, autophagy, and other forms of cell death. Accumulating evidences suggest that brain iron overload is involved in the pathogenesis of demyelinating diseases of the central nervous system (CNS), such as multiple sclerosis (MS), neuromyelitis optica (NMO), and acute disseminated encephalomyelitis (ADEM). The study of ferroptosis may provide a new understanding of demyelinating diseases and provide a novel therapeutic target for clinical treatment. Herein, we reviewed recent discoveries on mechanisms of ferroptosis, the effects of metabolic pathways on ferroptosis, and its involvement in CNS demyelinating diseases.image
The effect of severe imagery in advertising on charitable behavior and the moderating role of social closeness
Authors: Sung Billy , Septianto Felix , Stankovic Michelle 
Published: April 2023

AbstractThe present paper systematically investigated the effectiveness of utilizing severe or disgusting, imagery, and the moderating effect of social closeness within non‐profit health charity advertising appeals. Across three experiments, we found an interaction effect, whereby donations increased when severe images were shown, but only when high social closeness was also highlighted. Conversely, severe imagery reduced donations in the low social closeness condition, when participants were not prompted to think of their family. Despite the popularity of using severe imagery within charity advertising, our findings suggest that severe images should be used with caution in health charity marketing. Investigating the underlying mechanisms, we found that empathy (disgust) underlies the increase (decrease) of donation when severe imagery was used in a high (low) social closeness condition. Furthermore, we ruled out anger and perceived responsibility as competing moderators for these effects to verify whether other positive and negative emotions had similar effects.
Liminal (trans)formative spaces: A temporary escape from intersectionality
Authors: Davis Teresa , Paramanathan Gary 
Published: April 2023

AbstractThis paper is an examination of identity narratives of a small group of trans‐national transpeople in Australia. We reveal the complex identity journey undertaken by this group. Transpeople of Sub‐continental origin consume a temporarily transformational journey negotiating, resisting and subverting the dominant discourses that construct heterosexuality, gayness, whiteness and femininity. They carve out temporary liminal spaces of resistance within which to perform as “weekend women.” We identify transforming, transitioning, transcending across gender and ethnic boundaries, and see being enabled by specific transnational consumption imaginaries in liminal spaces meshed by intersectional of race/ethnicity and gender. We follow intertwined discourses that forms a “matrix of domination” and the way liminal thirdspaces create temporarily decolonized spaces that enable them to escape this matrix and perform a (trans)formative, movement back and forth between their weekday/weekend differently gendered/cultured selves. Ultimately, these decolonized thirdspaces bring only temporary release with inevitable return to their weekday male identity.
Nurses' and Families' perceptions and practices and factors influencing the implementation of family‐centred care for hospitalised children and their families
Authors: Wong Cho Lee , Phiri Patrick G. M. C. , Chan Carmen W. H. , Tse Mankei 
Published: April 2023

AbstractAims and ObjectivesTo explore the perceptions of family‐centred care among nurses and the family members of hospitalised children and investigate the facilitators of and barriers to the implementation of family‐centred care in Malawi.BackgroundIn Malawi, approximately 34% of children have long‐term illnesses that require hospitalisation. Family‐centred care ensures that the delivery of healthcare is grounded in partnerships between healthcare providers, patients and their families, which can improve the psychological well‐being of families. However, there is lack a good understanding of how families and nurses perceive this concept, its facilitators and the barriers.DesignThis was an exploratory qualitative study. Data were analysed deductively and inductively using the five‐step qualitative content analysis method.MethodsTwenty‐nine nurses and 31 families were recruited. Data were collected through in‐depth, semi‐structured and face‐to‐face individual interviews. The study was reported using the COREQ checklist.ResultsBoth nurses and families of hospitalised children recognised the importance of nurse–family partnerships in family‐centred care. Four themes emerged as follows: Perceptions of family‐centred care, elements of family‐centred care, facilitators of family‐centred care and barriers to family‐centred care. Specific information to families and the religious beliefs of families were identified as important facilitator and barrier to family‐centred care, respectively.ConclusionThe implementation of family‐centred care is promising in Malawi, as it is positively perceived by nurses and families, and its implementation is consistent with the Institute for Patient and Family‐Centred Care Framework.Relevance to clinical practiceOur findings present the best practices, gaps and challenges in the context of a low‐income country regrading implementation of family‐centred care. Education programmes on family‐centred care are crucial for sustaining the current gains.
Imaging biomarkers of cerebral edema automatically extracted from routine CT scans of large vessel occlusion strokes
Authors: Dhar Rajat , Kumar Atul , Chen Yasheng , Begunova Yelyzaveta , Olexa Madelynne , Prasad Ayush , Carey Grace , Gonzalez Isabella , Bhatia Kunal , Hamed Mohammad , Heitsch Laura , Mainali Shraddha , Petersen Nils , Lee Jin‐Moo 
Published: April 2023

AbstractBackground and PurposeVolumetric and densitometric biomarkers have been proposed to better quantify cerebral edema after stroke, but their relative performance has not been rigorously evaluated.MethodsPatients with large vessel occlusion stroke from three institutions were analyzed. An automated pipeline extracted brain, cerebrospinal fluid (CSF), and infarct volumes from serial CTs. Several biomarkers were measured: change in global CSF volume from baseline (ΔCSF); ratio of CSF volumes between hemispheres (CSF ratio); and relative density of infarct region compared with mirrored contralateral region (net water uptake [NWU]). These were compared to radiographic standards, midline shift and relative hemispheric volume (RHV) and malignant edema, defined as deterioration resulting in need for osmotic therapy, decompressive surgery, or death.ResultsWe analyzed 255 patients with 210 baseline CTs, 255 24‐hour CTs, and 81 72‐hour CTs. Of these, 35 (14%) developed malignant edema and 63 (27%) midline shift. CSF metrics could be calculated for 310 (92%), while NWU could only be obtained from 193 (57%). Peak midline shift was correlated with baseline CSF ratio (ρ = –.22) and with CSF ratio and ΔCSF at 24 hours (ρ = –.55/.63) and 72 hours (ρ = –.66/.69), but not with NWU (ρ = .15/.25). Similarly, CSF ratio was correlated with RHV (ρ = –.69/–.78), while NWU was not. Adjusting for age, National Institutes of Health Stroke Scale, tissue plasminogen activator treatment, and Alberta Stroke Program Early CT Score, CSF ratio (odds ratio [OR]: 1.95 per 0.1, 95% confidence interval [CI]: 1.52‐2.59) and ΔCSF at 24 hours (OR: 1.87 per 10%, 95% CI: 1.47‐2.49) were associated with malignant edema.ConclusionCSF volumetric biomarkers can be automatically measured from almost all routine CTs and correlate better with standard edema endpoints than net water uptake.
Stress and suicidal ideation among first‐generation farmers: A cross‐sectional study with 1,288 farmers in Georgia
Authors: Montgomery Anne , Basey Stephanie , Baucom Lily , Scoggins Chris 
Published: April 2023

AbstractPurposeThe suicide rate among farmers is higher than that of the overall working population. Literature on farmer mental health in Georgia (GA) has been scarce and mostly focused on suicide as a result. Literature on stressors or coping are mostly qualitative studies. This study looks at the influence of being a first‐generation farmer on farm‐related stressors and coping mechanisms.MethodsThis cross‐sectional study inventories mental well‐being, stressors, and coping mechanisms for different types of farmers in GA, USA. The online survey ran from January 2022 through April 2022. Participants (N = 1,288) were asked about demographics, work descriptors, health care access, specific stressors, stress levels, and coping mechanisms.FindingsTwo‐thirds of our sample were first‐generation farmers. First‐generation farmers had a higher stress score on average, as well as being more likely to feel depressed, and feel hopeless. They also showed less diverse coping mechanisms than generational farmers, with alcohol in their top 3 coping mechanisms. First‐generation farmers were also much more likely to experience suicidal ideation: 9% daily and 61% at least once in the past year (vs generational: 1% daily; 20% once in the past year). Binary logistic regression indicated that having more diverse coping mechanisms is a protective factor against suicidal ideation within the previous year. The same model indicated that being a farm owner or farm manager, being first‐generation, being unhappy with one's role, feeling sad or depressed, and feeling hopeless were all risk factors.ConclusionsFirst‐generation farmers experience more stress and exhibit more risk factors for suicidal ideation than generational farmers.
Non‐traumatic hemorrhagic myelopathy in dogs
Authors: West Natalie , Butterfield Sarah , Rusbridge Clare , Fernandez Ana , Tabanez Joana , Rudolf Nichola Jane , Archer Simon , Whittaker Danielle 
Published: April 2023

AbstractBackgroundNon‐traumatic spinal cord hemorrhage (NTSH) is an uncommon cause of myelopathy in dogs.ObjectivesDescribe the clinical characteristics, concurrent medical conditions and underlying causes, magnetic resonance imaging (MRI) findings and outcome in dogs with NTSH.AnimalsDogs diagnosed with NTSH using gradient echo T2‐weighted (GRE) sequences with or without histopathological confirmation of hemorrhage were included. Dogs with a traumatic cause were excluded, including those with compressive intervertebral disc extrusion.MethodsRetrospective descriptive study; the databases of 2 referral hospitals were searched between 2013 and 2021.ResultsTwenty‐three dogs met inclusion criteria. The onset of signs was acute and progressive in 70% of cases; spinal hyperesthesia was variable (48%). Hemorrhage was identified in the thoracolumbar spinal segments in 65% of dogs. An underlying cause was identified in 65% of cases. Angiostrongylus vasorum represented 18% of the total cohort, followed by steroid‐responsive meningitis arteritis (SRMA; 13%). Overall, 64% of dogs had a good or excellent outcome, regardless of cause; which was increased to 100% for SRMA, 75% for A. vasorum and 75% for idiopathic NTSH. Outcome was not associated with neurological severity. Recovery rate was 67% and 50% for nociception‐intact and nociception‐negative dogs, respectively.ConclusionsLarger prospective studies would be required to define prognostic factors for dogs with NTSH, but outcome appeared to be most influenced by the underlying cause, as opposed to neurological severity at presentation.
Subarachnoid hemorrhage and axonal degeneration after C1‐C2 cervical centesis in 2 horses
Authors: Luethy Daniela , Colmer Sarah , Jodzio Dayna , Bender Susan , Porter Erin , Hemmen Zena , Fultz Lisa , Craft William , Walker Randall , Johnson Amy , Holbrook Todd 
Published: April 2023

AbstractUltrasound‐guided cervical centesis has gained popularity as a method for collecting cerebrospinal fluid (CSF) from standing horses. There are anecdotal reports of neck stiffness, regional swelling, sensitivity to palpation, and fever after the procedure. We report 2 horses with complications that occurred within days of C1‐C2 centesis and ultimately resulted in euthanasia. Both C1‐C2 centesis were performed routinely, with CSF cytologic analysis providing no evidence of blood contamination. Post‐mortem examination revealed equine degenerative myeloencephalopathy as the primary disorder causing Horse 1's initial neurologic deficits, whereas Horse 2 did not have a distinct lesion explaining the horse's deficits. Both horses had evidence of subarachnoid hemorrhage at or near the centesis site with Wallerian axonal degeneration in the cranial cervical spinal cord. Although hemorrhage with associated axonal degeneration at the cervical centesis site appears to be rare, this complication of C1‐C2 centesis should be considered as this technique gains popularity.