bluuebunny/crossref_metadata_2025_split huggingface dataset:
Presencia de enfermedades no transmisibles en una población Chilena con periodontitis
Authors: Sierra-Cristancho Alfredo , Jimenez Constanza , Olave Franco , Bordagaray Maria Jose , Fernandez Alejandra , Benadof Dafna 
Published: January 2025

Introducción: Las enfermedades no transmisibles (ENT) son una carga importante en la mortalidad mundial. Se hipotetiza que la asociación entre la periodontitis y las ENT podría ser bidireccional. Objetivos: determinar la prevalencia de las enfermedades no transmisibles (ENTs) en individuos chilenos que padecen periodontitis, estratificándolos de acuerdo a la severidad de su condición periodontal. Métodos: Estudio cuantitativo, observacional, transversal. Se incluyeron pacientes inscritos en la Clínica de Periodoncia de la Universidad Andrés Bello. Se analizaron las fichas de los pacientes con una edad ≥18 años que contaban con historial clínico, registros médico-odontológicos y periodontogramas completos, entre marzo de 2017 hasta mayo de 2018. El diagnóstico periodontal se estableció siguiendo la clasificación de Page categorizada en leve o ausente, moderada y severa. Se documentó la existencia o ausencia de ENTs. Las ENTs se agruparon en: diabetes, afecciones cardiovasculares, complicaciones durante el embarazo, enfermedades respiratorias, problemas renales, artritis reumatoide, trastornos cognitivos, obesidad, cáncer, dislipidemias y psoriasis. Se calcularon las frecuencias absolutas, usando software estadístico Prism – GraphPad. Resultados: 152 individuos fueron incluidos, la mayoría del sexo femenino, con una edad promedio de 39.8 ± 14.8 años. Un 59.86% presentó periodontitis severa, un 21.71% periodontitis moderada y un 18% periodontitis leve/ausente. El 32.9% del total presentaron ENTs, de estas las más frecuentes fueron diabetes (11,84%), enfermedades cardiovasculares (9,87%) y obesidad (4,61%). La diabetes, enfermedad cardiovascular y obesidad se observó con mayor frecuencia en los pacientes que presentaban periodontitis en su forma leve. Conclusiones: En esta población de individuos con periodontitis, se registró una prevalencia del 32.9% de ENTs, siendo las enfermedades cardiovasculares y la diabetes los tipos más comunes. La periodontitis leves se asoció a mayor presencia de ENTs.
Implementasi Standard Operating Procedure (SOP) Penyelenggaraan Metting di Hotel Bintang Empat Padang : Sebuah Studi Kualitatif
Authors: Patricia Novira  , Hendri Azwar  
Published: January 2025

Abstract. The writing of this thesis aims to find out the implementation of the Standard Operating Procedure (SOP) for Organizing Meetings in Padang Four Star Hotels. The approach used in this research is descriptive qualitative. Observation, interviews, and documentation are used for the data collection process. There are 4 respondents from banquet employees, and 3 respondents from guests who have used meeting services at Hotel Bintang Empat Padang. By listening and transcribing and using NVivo software to analyze the data. The results of the research obtained that the implementation of the Standard Operating Procedure (SOP) for Organizing Meetings at the Four Star Hotel Padang has not been optimal. seen from the role of event technicians (engineering), officers, supervisors, and banquet managers who have not fully implemented properly according to the Standard Operating Procedure (SOP) that has been set. Companies can consider conducting training and periodic evaluation and supervision to ensure that all banquet employees have adequate knowledge of the Standard Operating Procedure (SOP).

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Pelatihan Penyusunan Proposal Sponsorship untuk Meningkatkan Kompetensi Organisasi Siswa Intra Sekolah SMAN 1 Blitar
Authors: Nunuk Latifah  , Rani Arifah Normawati  , Anna Widayani  
Published: January 2025

Organisasi Siswa Intra Sekolah (OSIS) merupakan organisasi resmi yang dibentuk di sekolah menengah, baik di tingkat SMP maupun SMA. OSIS berfungsi sebagai wadah bagi siswa untuk menyalurkan kreativitas dan berperan sebagai sarana pembelajaran yang mendukung pengembangan potensi siswa. Dalam pelaksanaannya, OSIS idealnya menyusun dan melaksanakan program kegiatan yang direncanakan secara matang, yang salah satu bentuknya adalah melalui penyusunan proposal sponsorship. Keberhasilan sebuah kegiatan sering kali bergantung pada kemampuan penyelenggara untuk menarik dukungan sponsor melalui proposal yang efektif, perlu dirancang dengan baik. Namun, permasalahannya adalah pengurus OSIS SMAN 1 Blitar menghadapi berbagai kendala dalam penyusunan proposal sponsorship. Berdasarkan wawancara awal dengan pihak sekolah, diketahui bahwa pengurus mengalami kesulitan dalam memenuhi standar kelengkapan unsur proposal, kelayakan isi, dan penggunaan bahasa. Sehingga perlu adanya pelatihan sebagai solusi penting untuk meningkatkan keterampilan pengurus OSIS dalam menyusun proposal sponsorship. Tujuan dari kegiatan ini diharapkan pengurus OSIS dan siswa dapat memahami pola bahasa tertulis yang tepat, sistematika penyusunan yang benar, serta cara menyampaikan gagasan atau pesan secara logis dan persuasif dalam merancang proposal sponsorship. yang menarik, baik dari sisi kelengkapan unsur maupun tata bahasa. Sasaran kegiatan ini adalah 50 orang yang terdiri dari pengurus OSIS dan anggota kegiatan sekolah lainnya. Kegiatan pengabdian kepada masyarakat ini dilaksanakan pada hari Jumat tanggal 8 Maret 2024. Hasil dari kegiatan pengabdian ini adalah peningkatan pemahaman dan keterampilan peserta dalam menyusun proposal sponsorship yang efektif dan profesional. Melalui kombinasi metode ceramah, diskusi interaktif, dan praktik langsung, peserta memperoleh wawasan mendalam mengenai pentingnya sponsorship serta keterampilan praktis dalam merancang proposal sponsorship yang menarik
Pentingnya Peran Kepala Sekolah dan Guru Dalam Meningkatkan Prestasi Siswa di Sekolah Dasar
Authors: Indriyanti Lina , Metta Caroline Setiadi  , Ni Wayan Setiyawati Astin Bakti  , Ahmad Suriansyah  , Celia Cinantya  
Published: January 2025

Pendidikan merupakan suatu hal yang sangat penting dalam menentukan perkembangan dan perwujudan diri individu, dan bagi kehidupan suatu bangsa. Menyadari akan pentingnya peranan pendidikan sebagai pendorong kemajuan suatu bangsa, maka pemerintah senantiasa berupaya untuk mengadakan pembaruan-pembaruan bidang pendidikan terutama yang berkaitan dengan tenaga pendidikan, pembiayaan, sistem, kurikulum, dan lain sebagainya adalah peningkatan mutu pendidikan. Tujuan penelitian ini adalah untuk mengeksplorasi peran kepala sekolah dan guru dalam meningkatkan prestasi siswa di SD serta mengidentifikasi faktor-faktor yang mempengaruhi efektivitas kolaborasi antara keduanya, metode pengumpulan data ini dilakukan dengan observasi langsung dan juga wawancara kepada kepala sekolah dan guru, kami menggunakan model penelitian kualitatif adalah pendekatan penelitian yang fokus pada pemahaman mendalam terhadap fenomena sosial, perilaku, dan pengalaman individu atau kelompok. Penelitian kualitatif menggunakan data deskriptif, baik lisan maupun tulisan, untuk menggambarkan dan menganalisis konteks serta makna dari fenomena yang diteliti.
Inovasi Tpack Dalam Pembelajaran IPAS Kelas 2 SD Negeri 1 Gumul
Authors: Ayuna Asri Nurrohmah  , Hani Binti Rishadi  , Isna Rahmawati  
Published: January 2025

Education is an effort made to increase potential, skills, and knowledge both physically and spiritually through teaching and training. Education is a crucial thing in the development of a country. This study uses a qualitative descriptive type of research. This descriptive research has the purpose of providing an overview of a certain symptom, meaning that information about the symptoms to be studied is available which is then described in more detail and depth according to the research problem. TPACK (Technological Pedagogical Content Knowledge) is a conceptual that describes the combination of knowledge needed by an educator to integrate technology in learning effectively. This study shows that TPACK integration is already effective in this class. The use of short narrative videos as a learning medium has increased students' enthusiasm and engagement compared to previous learning methods. The implementation of TPACK has made the learning process more interesting, collaborative, and improved students' ability to absorb the material taught.
Perkembangan Sistem Pendidikan di Swedia
Authors: Raysa Azzahra  , Mislaini  , Aidil Zulfikar  
Published: January 2025

Pendidikan di swedia memiliki kualitas yg sangat bagus yang di karenakan kondisi Negara swedia yg sangat maju dan tingkat ekonomi dan keamanan yg tingga yang menjadikan swedia memiliki tingkat pendidikan yg berikualitas, tetapi di sisi lain ada kelemahan nya juga. Lantaranya adalah kehidupan di swedia yg segalanyas serba mahal dan memiliki kebutuhan ekonomi yg tinggi sehingga membuat kita harus bekerja extra untuk bertahan hidup dan menuntut ilmu di sana. Saat ini, Swedia menawarkan pendidikan gratis dari tingkat dasar hingga universitas, menekankan pembelajaran berbasis siswa, inovasi, dan keberlanjutan. Penelitian ini bertujuan untuk memahami bagaimana kebijakan, pendekatan pengajaran, dan integrasi teknologi telah meningkatkan kualitas pendidikan di Swedia. Hasil kajian menunjukkan bahwa keberhasilan sistem ini terletak pada fleksibilitas kurikulum, kualitas guru, serta dukungan kolaboratif antara pemerintah dan masyarakat. Kesimpulannya, model pendidikan Swedia membuktikan bahwa pendekatan inklusif dan berorientasi masa depan dapat menciptakan sistem pendidikan yang berdaya saing global sekaligus responsif terhadap kebutuhan Masyarakat.
Health Counselling on Coping With Stress And Making Peace with Diabetes Mellitus in Coastal Areas of South Kalimantan
Authors: Tutpai Gertudis , Unja Ermeisi Er , Ayu Maria Frani 
Published: January 2025

One of the non-communicable diseases (NCDs), which causes the most serious threat to health in the world is diabetes mellitus. Data from the Tanah Laut District Health Office shows that the prevalence of type II DM in 2023 will increase to 5053 people. Based on these results, it is considered necessary to make an effort to prevent Diabetes Mellitus by providing counselling on how to prevent and control diabetes mellitus. The method of community service carried out is to conduct educational and participatory counselling with pre and post tests.This community service activity was carried out on Wednesday 18 December 2023 in the Takisung Health Centre work area, Tanah Laut Regency. The results obtained were that there was an increase in community knowledge about stress management and diet in patients with diabetes mellitus in the Takisung area, Tanah Laut. People who previously did not know that stress can also be one of the things that can trigger an increase in blood sugar in diabetes mellitus patients, after counselling they know many things that can cause diabetes mellitus. The community also understands how to deal with stress and prevent stress from occurring. It is hoped that health centre staff can carry out routine counselling activities in the Takisung area to control the incidence of Diabetes mellitus.
Driving Individual Performance: The Mediating Role of Innovation and Moderating Impact of Work-Life Balance among Indonesia's Professional Village Facilitators
Authors: Jatmiko Udik , Pribadiyono  , Suhermin  
Published: January 2025

Aims: This study investigates the role of Innovative Work Behavior (IWB) in mediating the effects of Job Crafting and Work Integrity on Individual Performance among professional village facilitators in Kediri Regency, Indonesia. Additionally, it examines the moderating effect of Work-Life Balance on the relationship between IWB and Individual Performance.
Study Design: The research adopts a quantitative approach to explore the interrelations between the variables, focusing on professional village facilitators in a specific regional context.
Methodology: This Research using by complete enumeration sampling (census), data were collected through offline surveys from 203 respondents and analyzed using Structural Equation Modeling (SEM). The variables studied include Job Crafting, Work Integrity, Innovative Work Behavior, Individual Performance, and Work-Life Balance.
Results: The result of study is Job Crafting and Work Integrity significantly influence Innovative Work Behavior. Job Crafting, Work Integrity, and Innovative Work Behavior do not significantly affect Individual Performance. Innovative Work Behavior does not mediate the relationship between Job Crafting, Work Integrity, and Individual Performance. Work-Life Balance does not moderate the relationship between Innovative Work Behavior and Individual Performance.
Conclusion: The findings suggest that Job Crafting, Work Integrity, and Innovative Work Behavior are not significant contributors to Individual Performance among professional village facilitators in Kediri Regency. This highlights the need to explore alternative mediating and moderating variables to better understand the factors influencing their performance. However, as IWB does not directly improve individual performance (IP), strategies should also address performance outcomes through targeted training, performance monitoring, and support mechanisms.
Costs and Causes of Oncology Drug Attrition With the Example of Insulin-Like Growth Factor-1 Receptor Inhibitors
Authors: Jentzsch Valerie , Osipenko Leeza , Scannell Jack W. , Hickman John A. 
Published: July 2023

ImportanceThe development of oncology drugs is expensive and beset by a high attrition rate. Analysis of the costs and causes of translational failure may help to reduce attrition and permit the more appropriate use of resources to reduce mortality from cancer.ObjectiveTo analyze the causes of failure and expenses incurred in clinical trials of novel oncology drugs, with the example of insulin-like growth factor-1 receptor (IGF-1R) inhibitors, none of which was approved for use in oncology practice.Design, Setting, and ParticipantsIn this cross-sectional study, inhibitors of the IGF-1R and their clinical trials for use in oncology practice between January 1, 2000, and July 31, 2021, were identified by searching PubMed and ClinicalTrials.gov. A proprietary commercial database was interrogated to provide expenses incurred in these trials. If data were not available, estimates were made of expenses using mean values from the proprietary database. A search revealed studies of the effects of IGF-1R inhibitors in preclinical in vivo assays, permitting calculation of the percentage of tumor growth inhibition. Archival data on the clinical trials of IGF-1R inhibitors and proprietary estimates of their expenses were examined, together with an analysis of preclinical data on IGF-1R inhibitors obtained from the published literature.Main Outcomes and MeasuresExpenses associated with research and development of IGF-1R inhibitors.ResultsSixteen inhibitors of IGF-1R studied in 183 clinical trials were found. None of the trials, in a wide range of tumor types, showed efficacy permitting drug approval. More than 12 000 patients entered trials of IGF-1R inhibitors in oncology indications in 2003 to 2021. These trials incurred aggregate research and development expenses estimated at between $1.6 billion and $2.3 billion. Analysis of the results of preclinical in vivo assays of IGF-1R inhibitors that supported subsequent clinical investigations showed mixed activity and protocols that poorly reflected the treatment of advanced metastatic tumors in humans.Conclusions and RelevanceFailed drug development in oncology incurs substantial expense. At an industry level, an estimated $50 billion to $60 billion is spent annually on failed oncology trials. Improved target validation and more appropriate preclinical models are required to reduce attrition, with more attention to decision-making before launching clinical trials. A more appropriate use of resources may better reduce cancer mortality.
Lateral Meristems
Authors: Fatz Wiktoria , Woodward George Malcolm , Vainio Leo , Topcu Melis Kucukoglu 
Published: July 2023

Abstract

Secondary or lateral growth increases the girth of plant organs in dicots and gymnosperms. It is achieved by the coordinated activities of lateral meristems, namely the vascular cambium and cork cambium (phellogen). The vascular cambium produces the conductive tissues secondary xylem (wood) and secondary phloem (bark), while the cork cambium generates the protective phellem (cork) against stresses from the surrounding environment. These meristematic tissues contain the stem cells to generate new tissues continuously and represent the hallmarks of perennial growth habit.

Key Concepts

Lateral meristems are responsible for the girth growth of plant organs.

Lateral meristems consist of the vascular cambium and cork cambium (phellogen), which produces the conductive tissues and protective tissues for the growing plant body, respectively.

The vascular cambium is uniseriate, and a single, bifacial stem cell produces both phloem and xylem cells in a cell file.

Development and activity of the vascular cambium are complex and governed by the genetic factors and plant hormones.

Phellogen initiation requires the activation of the vascular cambium formation.

Recent advances and tools developed for sequencing, imaging and segmentation will improve our understanding and modelling of plant lateral growth.
Acceptor Functionalization via Green Chemistry Enables High‐Performance n‐Type Organic Electrochemical Transistors for Biosensing, Memory Applications
Authors: Wang Yazhou , Koklu Anil , Zhong Yizhou , Chang Tianrui , Guo Keying , Zhao Chao , Castillo Tania Cecilia Hidalgo , Bu Zhonggao , Xiao Chengyi , Yue Wan , Ma Wei , Inal Sahika 
Published: July 2023

AbstractThe organic electrochemical transistor (OECT) is one of the most versatile building blocks within the bioelectronics device toolbox. While p‐type organic semiconductors have progressed as OECT channel materials, only a few n‐type semiconductors have been reported, precluding the development of advanced sensor‐integrated OECT‐based complementary circuits. Herein, green aldol polymerization is uses to synthesize lactone‐based n‐type conjugated polymers. Fluorination of the lactone‐based acceptor endows a fully locked backbone with a low‐lying lowest unoccupied molecular orbital, facilitating efficient ionic‐to‐electronic charge coupling. The resulting polymer has a record‐high n‐type OECT performance with a high product of mobility and capacitance (µC* = 108 F cm−1 V−1 s−1), excellent mobility (0.912 cm2 V−1 s−1), low threshold voltage (0.02 V), and fast switching speed (τON, τOFF = 336 µs,108 µs). This work demonstrates two types of device architectures and applications enabled by the high performance of this n‐type OECT, i.e., an artificial synapse and a complementary amplifier for detecting α‐synuclein, a potential biomarker of Parkinson's disease. This study shows that materials that enable high gain and fast speed n‐type OECTs can be developed via a green polymerization route, and the diverse form factors that these devices take promise for exploration of other application areas.
Device‐Level Optimization ofn‐Type Mg3(Sb, Bi)2‐Based Thermoelectric Modules toward Applications: A Perspective
Authors: Xu Congcong , Liang Zhongxin , Song Shaowei , Ren Zhifeng 
Published: July 2023

AbstractIn recent decades, improvements in thermoelectric material performance have made it more practical to generate electricity from waste heat and to use solid‐state devices for refrigeration. However, despite the development of successful strategies to enhance the figure‐of‐meritzT, optimizing devices for large‐scale applications remains challenging. HighzTvalues do not guarantee excellent device performance, and maintaining highzTover a wide temperature range is difficult. Thus, device‐level structural optimization is crucial for maximizing overall energy conversion efficiency. Proper interfacial and structure design strategies, including contact layer selection, multi‐stage optimization, and size matching for then‐ andp‐type thermoelectric legs, are necessary for advancing device performance. Additionally, thermal stability issues, device assembly techniques, mechanical properties, and manufacturing costs are crucial considerations for large‐scale applications. To achieve actual applications, the thermoelectric community must look beyond simply aiming for highzTvalues. This article focuses on modules based onn‐type Mg3(Sb, Bi)2, one of the most promising commercially available thermoelectric materials, and discusses the influence of various parameters on the modules and on the corresponding device‐level optimization strategies.
Defect and Interface Engineered Tungsten Bronze Superstructure Anode toward Advanced Sodium Storage
Authors: Xiong Xuhui , Liu Zhengwang , Yang Liting , Liang Guisheng , Zhang Ruixuan , Cheng Yifeng , Liu Jiwei , Zhang Jincang , Che Renchao 
Published: July 2023

AbstractDefect and interface engineering, which can facilitate exceptional electrochemical stability and activity, are some of the most important strategies in devising electrode materials. However, the complex nanoscale chemistry and structure characteristics make the origin of electrochemical mechanism extremely difficult to understand. To eliminate this issue, the delicately designed 1D tungsten bronze superstructure anode, guided by defect and interface engineering, is successfully prepared for sodium storage to gain insight into the endogenous structure‐property relationships. It can realize the intensely enhanced Na+‐storage performance with a safe operating potential of ≈0.5 V, a high specific capacity of 228 mAh g−1 at 0.1 C and superior rate performance, which is attributed to the rapid electron and ion transfer process induced by abundant heterointerfaces. More importantly, it can convey an ultra‐stable long‐term cycling performance, with the capacity retention close to 90% after 4500 cycles at 5 C and 10000 cycles at 10 C, which can be explained by the inherently zero‐strain characteristic of a novel vacancy‐ordered superstructure in tungsten bronze Ba3.4Nb10O28.4 (BNO). This study reveals the structural origins of defect and interface engineering responsible for electrochemical mechanism, providing critical insight into the design of superior electrode materials.
Color‐Tunable, Excitation‐Dependent, and Water Stimulus‐Responsive Room‐Temperature Phosphorescence Cellulose for Versatile Applications
Authors: Peng Fang , Chen Yian , Liu Hongchen , Chen Pan , Peng Feng , Qi Haisong 
Published: July 2023

AbstractSmart‐response materials with ultralong room‐temperature phosphorescence (RTP) are highly desirable, but they have rarely been described, especially those originating from sustainable polymers. Herein, a variety of cellulose derivatives with 1,4‐dihydropyridine (DHP) rings are synthesized through the Hantzsch reaction, giving impressive RTP with a long lifetime of up to 1251 ms. Specifically, the introduction of acetoacetyl groups and DHP rings promotes the spin‐orbit coupling and intersystem crossing process; and multiple interactions between cellulose induce clustering and inhibit the nonradiative transitions, boosting long‐live RTP. Furthermore, the resulting transparent and flexible cellulose films also exhibit excitation‐dependent and color‐tunable afterglows by introducing different extended aromatic groups. More interestingly, the RTP performance of these films is sensitive to water and can be repeated in response to wet/dry stimuli. Inspired by these advantages, the RTP cellulose demonstrates advanced applications in information encryption and anti‐counterfeiting. This work not only enriches the photophysical properties of cellulose but also provides a versatile platform for the development of sustainable afterglows.