bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relational sanctification, communal coping, and depression among African American couples
Authors: Skipper Antonius D. , Rose Andrew H. , Card Noel A. , Moore Travis James , Lavender‐Bratcher Debra , Chaney Cassandra 
Published: August 2023

AbstractDespite the common use of religious buffers, African Americans are disproportionately affected by depressive symptoms. Communal coping may serve as one factor in helping religious African American couples alleviate the symptoms of depression. This study examines the association between relational sanctification and depressive symptoms as mediated by the communal coping of 467 African American married and cohabiting couples. Data from the sampled couples were analyzed using a common fate model, and analyses revealed higher scores on the measure of sanctification were associated with more communal coping; more communal coping was associated with fewer depressive symptoms among women and men, and communal coping acted as a mediator between relational sanctification and depressive symptoms in both partners. Findings from this study underscore the importance of considering how the religiosity and cooperative action of African American couples relate to depressive symptoms.
Gynostemma pentaphyllum Makino extract induces hair growth and exhibits an anti‐graying effect via multiple mechanisms
Authors: Liu Xiaojin , Lv Xiaobing , Ji Tiancheng , Hu Haoya , Chang Lei 
Published: August 2023

AbstractBackgroundIn traditional Asian medicine, Gynostemma pentaphyllum Makino leaf extract (Gp) is used to treat aging, metabolic syndrome, diabetes, and neurodegenerative diseases. Hair loss and hair‐graying are common phenomena that haunt everyone. However, whether Gp activities on inhibition of hair loss and getting gray have been rarely studied.AimStudy the Gp activity and mechanism by in vivo and in vitro experiments to explore its application on hair health.MethodsIn the present study, we determined the effects of Gp on the expression of hair growth‐related genes and proliferation of human dermal papilla cells (hDPCs). Furthermore, Gp was topically applied to the hair‐shaved skin of male C57BL/6 mice, and the histological profile of the skin was studied. Because emotional stress may lead to melanocyte disappearance, norepinephrine‐exposed mice B16 melanocytes were treated with Gp to elucidate the anti‐hair graying capacity of Gp in response to this stress type.ResultsGp stimulated the proliferation of hDPCs and the Wnt signaling pathways associated with hair growth; furthermore, the expression of the hair loss‐related gene transforming growth factor‐β1 was suppressed. Gp treatment significantly increased the size of hair follicles in the treated mice and stimulated them. Moreover, Gp not only increased melanin synthesis but also tyrosinase activity in B16 cells. Quantitative real‐time polymerase chain reaction revealed that Gp increased melanin synthesis by increasing the expression of tyrosine‐related protein‐1, tyrosine‐related protein‐2, tyrosinase, and microphthalmia‐associated transcription factor.ConclusionOur study provides preclinical evidence regarding the potential of Gp as a promising hair growth and anti‐graying agent.
Defining thresholds to support noncomparative sensory claims based on home use test results: Application to a new lip balm
Authors: Perrin Lucie , Noharet Julie , Pezzini Chiara , Peres Lisa 
Published: August 2023

AbstractCosmetic product claims are subject to many regulations to ensure consumers are not misled. Claims must also be relevant to consumers, requiring robust and validated data to support them. Noncomparative claims are investigated utilizing a database of consumer reactions to a wide range of cosmetic products. A procedure based on product attribute ratings and related count based proportions was developed to set performance thresholds that were used to validate new claims. A consumer study was conducted to test the new procedure on lip balm products. Attributes were rated on Days 1 and 10 to establish product performance shifts during use, while the inclusion of two products helped establish if the new procedure could identify and validate the strengths of each product. Results from the database indicated that including count‐based proportions in addition to mean ratings added robustness to the performance levels that could be used to validate noncomparative claims.Practical ApplicationsThe new ISO standard for sensory claims sets out guidance to help ensure that relevant, robust and validated data are used to substantiate product claims. Many companies have substantial consumer data collected in recent years that can help ensure claims research is designed using consumer relevant product attributes. Just as important is that these data provide valuable information about levels of performance required for a product to deliver against the product and brand promise. This paper provides a methodology that could be adapted by companies, either in the non‐food or food sector, thus helping ensure new products can be launched and marketed with confidence.
‘It is not a mannequin disease’: A lived experience narrative of living with bulimia nervosa
Authors: Öcalan Sinem , Kovancı Mustafa Sabri , Hiçdurmaz Duygu 
Published: August 2023

Accessible SummaryWhat is known on the subject?

Bulimia nervosa is characterized by recurrent episodes of binge eating, inappropriate compensatory behaviours to prevent weight gain and excessive mental preoccupation with body weight and shape.

What the paper adds to existing knowledge?

In this paper, the feelings, thoughts and experiences of an individual with bulimia nervosa are explained, and the positive and negative effects of their experiences during the treatment process are emphasized.

This paper offers advice to patients, relatives and healthcare professionals in recognizing and treating bulimia nervosa.

What are the implications for practice?

Mental health nurses should organize training, seminars and conferences to raise awareness of society against bulimia nervosa, which is defined as a mannequin disease and therefore creates a positive perception.

Mental health nurses, an essential part of the health system, should raise awareness of individuals and families about recognizing, monitoring and supporting the early symptoms of bulimia nervosa.

AbstractIntroductionBulimia nervosa is one of the areas where mental health professionals have difficulties due to its nature and course. It is important to understand the factors related to this problem in‐depth to discover the dynamics unique to the individual that causes the difficulty, identify new perspectives on these dynamics and identify alternative behaviours, stop stubborn binge‐eating attacks and prevent relapse.AimIt is aimed to provide an in‐depth insight into the nature, course and treatment processes of bulimia nervosa through the narrative of the lived experience of an individual living with this problem.Implication for PracticeThe perception of beauty seriously impacts the onset and later course of bulimia nervosa and draws attention to the fact that mental health professionals and media workers have important duties to change the concept of beauty equals being skinny, created in society and the media. Quality of perceived social support is very important in preventing, treating and rehabilitating bulimia nervosa. Adopting a more objective approach, which will prevent the positive or negative stigmatization of the disease in explaining bulimia nervosa to the public, should be adopted.
Importance of Religion after Adversity
Authors: Frijters Paul , Johnston David W. , Knott Rachel J , Torgler Benno 
Published: August 2023

AbstractAfter major adversity, some people rely on their religious faith and networks for comfort, support, and material goods and services. Consistent with this behavior are findings that adversity has a positive causal effect on the importance of religion in people's lives. Using a large high‐frequency US dataset, we estimate the causal effects of natural disasters on stated religious importance and attendance at religious services. Effects are identified by comparing changes in outcomes over time within counties affected by a natural disaster with changes over time in other counties from the same state. We find that most estimates are near‐zero in magnitude; for the full sample, for subgroups defined by religious affiliation, demographics, and income, and for different disaster types. However, significant negative effects are found immediately postdisaster, suggesting a short‐term crowding‐out effect in which recovery activities limit time for worship. This explanation is supported by a finding that people are less “well rested” in the first weeks postdisaster.
Mitigating the impact of winter temperatures on striped catfish (Pangasianodon hypophthalmus) using functional feed additives
Authors: Bano Sheeza , Khan Noor , Fatima Mahroze , Khalique Anjum , Arslan Murat , Wan Alex H. L. 
Published: August 2023

AbstractThe drop in temperature during the winter months can lead to a decrease in growth, induce metabolic stress, and increase mortality incidences. The present study evaluated the potential of functional feed additives in mitigating the negative impacts of winter‐rearing conditions in striped catfish (Pangasianodon hypophthalmus). Four test diets were evaluated over a twelve‐week feed trial: (1) zinc‐acetate (Zn‐acetate), (2) selenomethionine (Se‐Met), (3) β‐glucan, and (4) control with no added feed additive. The survival rate in the β‐glucan (95.00%) and Zn‐acetate (93.30%) dietary groups was higher than the control (78.30%) and Se‐Met (85.00%). Fish fed with the β‐glucan had the highest weight gain (20.75% increase), specific growth rate (13.75% increase), and lower feed conversion ratio (9.64 % decrease). However, feed additives did not influence the fatty acid profiles or whole‐body proximate composition. Although, Zn‐acetate and Se‐Met had higher body ash content. Serum cortisol and glucose levels were lower in β‐glucan and Zn‐acetate than in other treatment groups. All feed additives resulted in higher superoxide dismutase, glutathione peroxidase, and catalase activity in the liver and muscle. This study found that β‐glucan and zinc‐acetate can improve cold stress resistance and offer a sustainable strategy for catfish rearing over winter.
Investigating the role of lipid genes in liver disease using fatty liver models of alcohol and high fat in zebrafish (Danio rerio)
Authors: Shihana Fathima , Cholan Pradeep Manuneedhi , Fraser Stuart , Oehlers Stefan H. , Seth Devanshi 
Published: August 2023

AbstractBackgroundAccumulation of lipid in the liver is the first hallmark of both alcohol‐related liver disease (ALD) and non‐alcohol‐related fatty liver disease (NAFLD). Recent studies indicate that specific mutations in lipid genes confer risk and might influence disease progression to irreversible liver cirrhosis. This study aimed to understand the function/s of lipid risk genes driving disease development in zebrafish genetic models of alcohol‐related and non‐alcohol‐related fatty liver.MethodsWe used zebrafish larvae to investigate the effect of alcohol and high fat to model fatty liver and tested the utility of this model to study lipid risk gene functions. CRISPR/Cas9 gene editing was used to create knockdowns in 5 days post‐fertilisation zebrafish larvae for the available orthologs of human cirrhosis risk genes (pnpla3, faf2, tm6sf2). To establish fatty liver models, larvae were exposed to ethanol and a high‐fat diet (HFD) consisting of chicken egg yolk. Changes in morphology (imaging), survival, liver injury (biochemical tests, histopathology), gene expression (qPCR) and lipid accumulation (dye‐specific live imaging) were analysed across treatment groups to test the functions of these genes.ResultsExposure of 5‐day post‐fertilisation (dpf) WT larvae to 2% ethanol or HFD for 48 h developed measurable hepatic steatosis. CRISPR‐Cas9 genome editing depleted pnpla3, faf2 and tm6sf2 gene expression in these CRISPR knockdown larvae (crispants). Depletion significantly increased the effects of ethanol and HFD toxicity by increasing hepatic steatosis and hepatic neutrophil recruitment ≥2‐fold in all three crispants. Furthermore, ethanol or HFD exposure significantly altered the expression of genes associated with ethanol metabolism (cyp2y3) and lipid metabolism‐related gene expression, including atgl (triglyceride hydrolysis), axox1, echs1 (fatty acid β‐oxidation), fabp10a (transport), hmgcra (metabolism), notch1 (signalling) and srebp1 (lipid synthesis), in all three pnpla3, faf2 and tm6sf2 crispants. Nile Red staining in all three crispants revealed significantly increased lipid droplet size and triglyceride accumulation in the livers following exposure to ethanol or HFD.ConclusionsWe identified roles for pnpla3, faf2 and tm6sf2 genes in triglyceride accumulation and fatty acid oxidation pathways in a zebrafish larvae model of fatty liver.
Malignant transformation in oral submucous fibrosis: Tertiary level evidence: An umbrella review
Authors: Gondivkar Shailesh M. , Yuwanati Monal , Sarode Sachin C. , Gadbail Amol R. , Gondivkar Rima , Mohsin Syed Fareed , Gaikwad Rahul 
Published: August 2023

AbstractObjectivesAn umbrella review is a systematic review of systematic reviews, which provides a tertiary level of evidence. This umbrella review of systematic reviews and meta‐analysis (SR‐MA) aimed to determine the proportion of oral cancer (OC) development in oral submucous fibrosis (OSF) patients.Materials and MethodsWe searched electronic databases including PubMed, Scopus, Web of Science, Cochrane and grey literature. Two reviewers independently screened abstracts and assessed for eligible papers. The methodological quality of SR‐MA was evaluated using AMSTAR2, and we also checked the quality of evidence of the included papers.ResultsOut of 454 papers identified in the primary search, 105 underwent eligibility screening. Inclusion criteria were met by four SR‐MA. OC ratios ranged between 4.2% and 6% for OSF. Substantial heterogeneity was observed for this outcome in all four MA (I2 = 71.31% to 86.37%). None of the SRs assessed the quality of evidence, and half of them were judged to be of critically low methodological quality.ConclusionThere is lack of quality of evidences and critically low methodological quality among SRs and MA leading to substantial heterogeneity. However, due to potentially malignant nature, OSF patients should be monitored carefully for early detection of OC.
PANoptosis is a compound death in periodontitis: A systematic review of ex vivo and in vivo studies
Authors: Zhang Aopeng , Zhang Chenchen , Zhang Yuhan , Hu Tao , Cheng Ran 
Published: August 2023

AbstractObjectiveThe purpose of the systematic review is to verify the presence of PANoptosis in periodontitis based on the published literatures studying cell death in periodontitis.Materials and MethodsWe conducted a comprehensive review of literature studying the types of cell death in vitro cellular experiments, in vivo rodent studies and clinical studies from three major databases: PubMed, Scopus, and Web of Science. The present systematic review was recorded in the PROSPERO database, under registration number CRD42022383456.ResultsIn total, 51 articles were included in this study. Our analysis of in vitro cell models revealed that pyroptosis, necroptosis, and apoptosis could be induced by periodontal pathogens in macrophages, fibroblasts, stem cells, and periodontal ligament cells. Furthermore, three types of cell death were detected in in vivo rodent periodontitis models. Clinical studies on human periodontitis tissue specimens and gingival crevicular fluid (GCF) showed that some key proteins related to pyroptosis, necroptosis, and apoptosis were elevated in periodontitis.ConclusionsVarious studies have established similar in vivo and in vitro models with three modes of death detected under the same conditions, revealing complex interactions between different types of cell death pathways in periodontitis and the potential for PANoptosis to occur in periodontitis.
Attaining environmental sustainability amidst the interacting forces of natural resource rent and foreign direct investment: Is Norway any different?
Authors: Udemba Edmund Ntom , Dagar Vishal , Peng Xuhu , Dagher Leila 
Published: August 2023

AbstractThis is a study of Norway's sustainable environment development amidst the interactions of natural resources, external investment (FDI) and economic development. Much has been done with respect to the study of Norway's economic performance in relation to the link between the natural resources and FDI with little emphasis on the environmental performance of the resource‐based economy. Also, Norway is classified as among the top countries in Europe with a greater percentage of adopting renewable energy, and no study has done a critical review of the impact of natural resources and FDI which are part of drivers of carbon emission that can counter the positive impact of renewable energy towards the Norway's sustainable environment. On this basis, this study adopts a time series data of Norway, 1970 to 2018 to study its environmental performance. Approaches such as structural break analysis, Autoregressive Distributed Lag (ARDL)‐bound testing and Granger causality estimations are utilised in this study for in‐depth analysis of the subject. Findings from ARDL confirmed a positive association between fuels and carbon emission, other indicators (economic growth and natural resources) are improving the quality of the country's environment. FDI even though shows positive sign remains insignificant in impacting the environmental performance in the short run reverted to a significant negative relationship with carbon emissions. This confirms the pollution halo hypothesis and rejects the pollution haven hypothesis (PHH) for Norway, and this trend can be sustained with the constant implementation of environmental rules in the country. Granger test confirms, a one‐way transition from fossil fuels to carbon emission, from carbon emission to growth, and from economic growth to fossil fuels. Also, a two‐way transmission is found between fossil fuels and FDI. These findings from Granger causality are consistent with the findings from ARDL, hence, two ways interactions between FDI and fossil fuel energy source consumption from Granger causality and the two variables (fossil fuels and FDI) are seen impacting on Norway's environmental performance. Findings from the estimates suggest that natural resources and FDI are mitigating pollution, hence, Norway's policy is expected to be resources and FDI driven in sustainable environment development.
How personnel allocation affects performance: Evidence from Brazil's federal protected areas agency
Authors: Greenstein Gus 
Published: August 2023

AbstractMany government agencies operate with fewer personnel than they need to perform effectively. Yet little research has explored how agencies might allocate their personnel so as to maximize performance with the personnel they have. I address this gap through a study of Brazil's federal protected areas agency, which manages the world's third largest system of conservation areas. Based on 66 interviews and econometric analyses covering 322 administrative units, I find that three moderators influence the relationship between sub‐unit size and performance: the size of a sub‐unit's jurisdiction, a sub‐unit's likelihood of near‐term failure, and the strength of a sub‐unit's ties with local stakeholders. Personnel re‐allocation strategies informed by these factors may have reduced deforestation on the order of 26% over the agency's first decade. This study contributes a framework for analyzing the efficacy of personnel allocation strategies, with implications for management of one of the world's greatest natural assets.
Fascial plane blocks in children—Scientifically supported or not?
Authors: Lönnqvist Per‐Arne 
Published: August 2023

AbstractSince the introduction of Fascial Plane Blocks in 2007 there has been an enormous interest and application of Fascial Plane Blocks, evidenced by substantially more than 1000 PubMed items. Despite this gigantic number of publications, also including randomized controlled trials and meta‐analyses in children, there is still no clear‐cut insight into how much of the purported effect is in fact due to the blockade of nerve structures and how much is merely adding the well‐known analgesic and anti‐inflammatory effects of the plasma levels of local anesthetics that are achieved with these techniques. Furthermore, Fascial Plane Blocks appear useful only if compared to conventional multi‐modal analgesia (no block or placebo) and Fascial Plane Blocks lack the potency to provide surgical anesthesia on their own and appear only to be of value when used for minor‐moderate surgery. Despite the huge literature, there has so far not emerged any clinical situations where Fascial Plane Blocks have definitively been shown to be the block of choice, being decisively more effective than other established regional blocks. Lastly, Fascial Plane Blocks may appear as virtually free of complications, but case reports are emerging that point to a real risk for causing local anesthetic systemic toxicity when using Fascial Plane Blocks. This text aims to synthesize the current knowledge base regarding the Fascial Plane Blocks that are relevant to use in the pediatric context. In summary, there does currently not exist any convincing scientific evidence for the continued support for the use of Fascial Plane Blocks in children, except for the rectus sheath block and possibly also the transmuscular quadratus lumborum block.
Freedom, foreknowledge, and betting
Authors: Seymour Amy 
Published: August 2023

AbstractCertain kinds of prediction, foreknowledge, and future‐oriented action appear to require settled future truths. But open futurists think that the future is metaphysically unsettled: if it is open whetherpis true, then it cannot currently be settled thatpis true. So, open futurists—and libertarians who adopt the position—face the objection that their view makes rational action and deliberation impossible. I defuse the epistemic concern: open futurism does not entail obviously counterintuitive epistemic consequences or prevent rational action.