bluuebunny/crossref_metadata_2025_split huggingface dataset:
The use of water allocation efficiency in optimizing crop production in drylands using a fuzzy trading model
Authors: Liang Yuan , Bi Wentai 
Published: September 2023

Abstract
Considering the importance of agriculture in food security in arid and semiarid areas, it is absolutely necessary to apply the planning model based on different objectives. This study has been conducted to simulate the trading and non-trading policies in the Particle Swarm Optimization framework for estimating the optimal economic values of agricultural water in Jilin province, northeastern China. Fuzzy solutions have been also calculated by definition of the feasible domain for water availability and permits. A generalized extreme value function was incorporated into the problem to predict the rainfall amounts with a 25-year return period. The results showed that determining the agricultural pattern using a trading policy with the aim of benefiting from the water will reduce the water demand in the study area. The trading policy can lead to a more efficient allocation of released water and reduce water scarcity, but it can eliminate some plants from the cropping pattern by reducing the water level. As a result, trading policy can be effective in the short term, especially in drought conditions due to insufficient water supply.
Physicochemical and bacteriological quality and safety of packaged drinking water in Ouagadougou, Burkina Faso
Authors: Traoré Oumar , Ouédraogo Nafissatou , Dembélé René , Kpoda Dissinviel Stéphane , Saba Courage Kosi Setsoafia , Bonkoungou Isidore Juste Ouindgueta , Barro Nicolas 
Published: September 2023

Abstract

Urban packaged water samples of Ouagadougou were studied in order to assess their bacteriological and chemical characteristics and suitability for potable purposes. The study also investigated the sanitation of the companies producing packaged water. Packaged water from 17 different brands was purchased and analyzed for physicochemical (turbidity, pH, EC, total hardness, NH4+, NO3-, HCO3-, SO42-, and Cl−) and bacteriological (total coliforms, Escherichia coli, Pseudomonas aeruginosa, Enterococcus, and sulphite-reducing anaerobic bacteria) parameters. The production sites investigation included: (1) distance between latrines and water sources superior to 15 m, (2) hygiene of handling personnel, (3) training of handling personnel on good hygiene practice and manufacturing, (4) hygiene of premises, and (5) hygiene of toilets. All the samples met the national guidelines for the physicochemical parameters investigated. Enterococcus, sulphite-reducing anaerobic bacteria spores, and E. coli were not found. Total coliforms were found in 8 (47.1%) in February, 9 (52.9%) in March, 2 (11.7%) in April, and 5 (29.4%) in May, while 7 (41.2%) brands were always in compliance with the guidelines. Some packaged waters were contaminated with total coliforms or P. aeruginosa above acceptable limits for human consumption. Regarding bacteriological contamination, it is necessary to reinforce water treatment systems in certain packaged water companies.
Ba-modified peanut shell biochar (PSB): preparation and adsorption of Pb(II) from water
Authors: Duan Qianqian , Yang Tianrui , Chen Jingyi , Liu Junsheng , Gao Liping , Zhang Junfei , Lin Shitao 
Published: September 2023

Abstract

The impact of Ba-modified peanut shell biochar (Ba-PSB) on Pb(II) removal was studied and BaCl2 was used as a modifier. It was shown that the PSB obtained at 750 °C had the best adsorption effect, and the Ba-PSB had a larger specific surface area and a good adsorption effect on Pb(II). At pH = 5, concentration was 400 mg/L, time was 14 h, and temperature was 55 °C, the loading amount of black peanut shell biochar (BPSB), red peanut shell biochar (RPSB), Ba-BPSB, and Ba-RPSB reached 128.050, 98.217, 379.330, and 364.910 mg/g, respectively. In addition, based on the non-linear fitting, it was found that the quasi-second-order kinetic model, and isothermal model could be applied to describe Pb(II) adsorption on PSB and Ba-PSB. The adsorption behavior of PSB unmodified and modified was a spontaneous process. Moreover, chemical modification of BPSB, RPSB, Ba-BPSB, and Ba-RPSB for hindering of –COOH and –OH groups revealed 81.81, 77.08, 86.90, and 83.65% removal of Pb(II), respectively, which was due to the participation of –COOH, while 17.61, 21.70, 12.77, and 15.06% was from –OH group, respectively. The increase of cation strength (Na+, K+, Ca2+, and Mg2+) will reduce the adsorption capacity of PSB for Pb(II).
Effects of Pregabalin as a Neural Pathway Inhibitor for the Treatment of
Resistant Subacute and Chronic Cough: A Pilot Clinical Trials Study
Authors: Adeli Seyed Hasan , Beigi Abolfazl Mohammad , Ahmadpour Sajjad , Habibi Mohammad Amin , Pashaei Mohammad Reza , Sharifipour Ehsan , Shakeri Mansoureh , Asghari Akram 
Published: September 2023

Background:
Cough hypersensitivity syndrome is one of the causes of chronic cough.
Small clinical trials have suggested the effects of pregabalin as a neural pathway inhibitor in
treating subacute and chronic cough resistance.

Methods:
This study is an 8-week, pilot study randomized, double-blind clinical trial on 30
patients’ resistant to treatment of the underlying cause who were referred to an ultra-specialized
lung clinic, Shahid Beheshti Hospital, between 2021-2022. The samples were randomly divided
into control (dextromethorphan and placebo) and intervention (dextromethorphan and
pregabalin). Patients were evaluated at the beginning, during, and after eight weeks of treatment,
using the modified standard Leicester Cough Questionnaire (LCQ) regarding the changes and the
rate of recovery compared to before Participation in the study.

Findings:
The quality of life score of patients eight weeks after treatment had a significant
difference and was higher in the intervention group (In the pregabalin group) than in the control
group (p =0.006). The recovery rate of cough in 26% of patients was equal to 70%, but others
were reported up to 50%.

Conclusion:
Pregabalin increases the quality of life in patients with subacute and chronic cough
resistant to standard treatment and increases the rate of recovery in these patients.
Testing a Digital Health App for Patients With Alcohol-Associated Liver Disease: Mixed Methods Usability Study
Authors: Park Linda S , Kornfield Rachel , Yezihalem Mihret , Quanbeck Andrew , Mellinger Jessica , German Margarita 
Published: September 2023

Background
Alcohol-associated liver disease (ALD) is increasingly common and associated with serious and costly health consequences. Cessation of drinking can improve ALD morbidity and mortality; however, support for cessation is not routinely offered to those diagnosed with ALD, and continued drinking or resumption of drinking after diagnosis is common. Mobile health (mHealth) has the potential to offer convenient and scalable support for alcohol cessation to those diagnosed with ALD, but mHealth interventions for alcohol cessation have not been designed for or evaluated in a population with ALD.

Objective
This study aims to understand how individuals with ALD would perceive and use an mHealth tool for alcohol cessation and to gather their perspectives on potential refinements to the tool that would allow it to better meet their needs.

Methods
We interviewed 11 individuals who attended clinic visits related to their ALD to elicit their needs related to support for alcohol cessation and views on how mHealth could be applied. After completing initial interviews (pre), participants were provided with access to an mHealth app designed for alcohol cessation, which they used for 1 month. Afterward, they were interviewed again (post) to give feedback on their experiences, including aspects of the app that met their needs and potential refinements. We applied a mixed methods approach, including a qualitative analysis to identify major themes from the interview transcripts and descriptive analyses of use of the app over 1 month.

Results
First, we found that a diagnosis of ALD is perceived as a motivator to quit drinking but that patients had difficulty processing the overwhelming amount of information about ALD they received and finding resources for cessation of alcohol use. Second, we found that the app was perceived as usable and useful for supporting drinking recovery, with patients responding favorably to the self-tracking and motivational components of the app. Finally, patients identified areas in which the app could be adapted to meet the needs of patients with ALD, such as providing information on the medical implications of an ALD diagnosis and how to care for their liver as well as connecting individuals with ALD to one another via a peer-to-peer support forum. Rates of app use were high and sustained across the entire study, with participants using the app a little more than half the days during the study on average and with 100% (11/11) of participants logging in each week.

Conclusions
Our results highlight the need for convenient access to resources for alcohol cessation after ALD diagnosis and support the potential of an mHealth approach to integrate recovery support into care for ALD. Our findings also highlight the ways the alcohol cessation app should be modified to address ALD-specific concerns.
Association of Unmet Social Needs With Metformin Use Among Patients With Type 2 Diabetes
Authors: Drake Connor , Alfaro Jorge Morales , Blalock Dan V. , Ito Kristin , Batch Bryan C. , Bosworth Hayden B. , Berkowitz Seth A. , Zullig Leah L. 
Published: September 2023

OBJECTIVE
To evaluate the relationship between social needs and metformin use among adults with type 2 diabetes (T2D).

RESEARCH DESIGN AND METHODS
In a prospective cohort study of adults with T2D (n = 722), we linked electronic health record (EHR) and Surescripts (Surescripts, LLC) prescription network data to abstract data on patient-reported social needs and to calculate metformin adherence based on expected refill frequency using a proportion of days covered methodology.

RESULTS
After adjusting for demographics and clinical complexity, two or more social needs (−0.046; 95% CI −0.089, 0.003), being uninsured (−0.052; 95% CI −0.095, −0.009) and while adjusting for other needs, being without housing (−0.069; 95% CI −0.121, −0.018) and lack of access to medicine/health care (−0.058; 95% CI −0.115, −0.000) were associated with lower use.

CONCLUSIONS
We found that overall social need burden and specific needs, particularly housing and health care access, were associated with clinically significant reductions in metformin adherence among patients with T2D.
Epigenome-Wide Meta-analysis Reveals Associations Between Dietary Glycemic Index and Glycemic Load and DNA Methylation in Children and Adolescents of Different Body Sizes
Authors: Ott Raffael , Stein Robert , Hauta-alus Helena H. , Ronkainen Justiina , Fernández-Barrés Sílvia , Spielau Ulrike , Kirsten Holger , Poulain Tanja , Melton Phillip E. , Küpers Leanne K. , Azaryah Hatim , Colombo Marco , Landgraf Kathrin , Tobi Elmar W. , O’Sullivan Therese , Huang Rae-Chi , Campoy Cristina , Winkler Christiane , Vioque Jesus , Vrijheid Martine , Kiess Wieland , Körner Antje , Sebert Sylvain , Jarvelin Marjo-Riitta , Ziegler Anette-G. , Hummel Sandra 
Published: September 2023

OBJECTIVE
Dietary glycemic index (GI) and glycemic load (GL) are associated with cardiometabolic health in children and adolescents, with potential distinct effects in people with increased BMI. DNA methylation (DNAm) may mediate these effects. Thus, we conducted meta-analyses of epigenome-wide association studies (EWAS) between dietary GI and GL and blood DNAm of children and adolescents.

RESEARCH DESIGN AND METHODS
We calculated dietary GI and GL and performed EWAS in children and adolescents (age range: 4.5–17 years) from six cohorts (N = 1,187). We performed stratified analyses of participants with normal weight (n = 801) or overweight or obesity (n = 386). We performed look-ups for the identified cytosine–phosphate–guanine (CpG) sites (false discovery rate [FDR] &lt;0.05) with tissue-specific gene expression of 832 blood and 223 subcutaneous adipose tissue samples from children and adolescents.

RESULTS
Dietary GL was positively associated with DNAm of cg20274553 (FDR &lt;0.05), annotated to WDR27. Several CpGs were identified in the normal-weight (GI: 85; GL: 17) and overweight or obese (GI: 136; GL: 298; FDR &lt;0.05) strata, and none overlapped between strata. In participants with overweight or obesity, identified CpGs were related to RNA expression of genes associated with impaired metabolism (e.g., FRAT1, CSF3).

CONCLUSIONS
We identified 537 associations between dietary GI and GL and blood DNAm, mainly in children and adolescents with overweight or obesity. High-GI and/or -GL diets may influence epigenetic gene regulation and thereby promote metabolic derangements in young people with increased BMI.
Pengaruh Lama Fermentasi Menggunakan Mikroba Ghalkoff terhadap Perubahan Konsentrasi Kandungan Kafein Kopi Robusta Organik Kabupaten Lampung Barat
Authors: Wijaya Riky Yan , Tamrin Tamrin , Sugianti Cicih 
Published: September 2023

Coffee is a beverage ingredient not only famous in Indonesia but also famous throughout the world. Caffeine is the most important compound found in coffee, caffeine functions as an element of taste and aroma in coffee beans. Excessive acid and caffeine content in coffee can have an impact on health. This study aims to determine the effect of fermentation time using microbial Ghalkoff on changes in concentration of caffeine, protein and acidity content in organic robusta coffee without reducing the taste of coffee. This research was conducted from July to August 2018 at PT. Ghaly Roelies Indonesia, Kecamatan Kemiling, Bandar Lampung. This study uses a laboratory and Kruskal-Wallis test Non-parametric statistical test based on questionnaire test on the level of preference. The results showed the effect of changes in the concentration of caffeine, protein and acidity levels in organic robusta coffee with control of the initial data resulting in a decrease in the concentration of caffeine by 27%. While the results of the N-Rank organoleptic test with Kruskal-WallisTest showed that administering long-acting organic coffee fermentation using microbial ghalkoff can increase the preference for coffee flavor, aroma and color. Keywords: Caffeine, Fermentation, Kruskal-Wallis Test, Organic Robusta Coffee.
Socio-economic Profile of Equine Owner, Morphometric Characterization and Reproductive Performance of Indigenous Horses in Bangladesh
Authors: Shahinur Rahman Md. , Mahbubul Mohammad , Khatun Asma , Younus Ali Md. 
Published: September 2023

Background: The socio-economic importance of horses plays a decisive role in the dynamism of rural economies in remote regions of developing countries such as Bangladesh. Horses are particularly suitable for transportation and recreation in these areas.
Methods: The study was conducted from January to March 2023 in 200 randomly selected horse families concentrated in Sherpur, Jamalpur, Tangail, Sirajganj, Natore, and Noagoan districts of Bangladesh. After the necessary corrections and modifications, the final questionnaire was created based on the objectives of the study. The data were collected by respondents individually through personal interviews.
Results: The average number of horses per family was 1.18, with 70% of them being transported and only 11.5% participating in horse races. The average peak and the poor seasonal income of the farmers were recorded as BDT (12,920-6,717). On average, 2 kg of concentrate feed per day is supplied to each horse with forages in the morning and afternoon depending on the situation. All farmers practiced natural mating, but they did not perform vaccination (100%). The indigenous horse's face color was observed as a star of 30%, and 45% non-specific, while the coat color was chestnut 38.5%, bay 41.5%, grey 8%, pseudo-Albino 3.5%, black 3.5%, brown 1% and bay roan 4%. The chest stocking color was observed as black 48%, white 33%, black and white 19%. The average body length, chest girth, neck length, ear length, and body weight in the research region were 119.86±0.17 cm, 126.28±0.19 cm, 37.87±0.14 cm, 15.78±0.12 cm, and 160.43±0.65 kg. The body length and body weight (p=0.000) differ significantly from region to region. Age at first service, service per conception (no.), gestation length, and foaling interval were 2.34±0.07 years, 1.21±0.06 years, 10.91±0.33 months and 1.00±0.03 years, respectively.
Conclusions: Horses have enormous potential for livelihoods in rural areas, so it is important to preserve and improve horse genetic resources and ensure sustainable horse rearing in Bangladesh.
Canine cognitive decline and Alzheimer disease: clinical insights to solve a shared one-health problem
Authors: Ehrenzweig Joel , Hunter Robert P. 
Published: September 2023

Abstract
Alzheimer disease (AD) is the leading cause of dementia among older adults. Current AD treatment options are limited, and the absence of appropriate research animals has significantly hindered the development of new AD therapies. Canine cognitive decline (CCD) is a major determinant of morbidity in older animals, with alterations in blood biomarkers, neuropathology, physiology, and behavior comparable to those seen in humans diagnosed with dementia and AD.
The one-health goal of achieving optimal health is supported by academics, researchers, and governments. Veterinarians’ ability to identify patients in the early stages of CCD is crucial to the successful implementation of interventions that can improve the quality of life of affected dogs. Timely identification of CCD also opens opportunities for innovative interdisciplinary research that will contribute to a better understanding of the underlying mechanisms, early detection, and effective treatments for AD, ultimately benefiting human health as well.
Until now, veterinary practitioners have played limited roles as interdisciplinary leaders in the One Health initiative to combat disease. The authors discuss how client-owned animals with spontaneous, naturally occurring CCD can play a significant role as disease-relevant surrogates for translational AD research. The proposed Dogs Overcoming Geriatric Memory and Aging (DOGMA) Study to be conducted in veterinary practices will analyze the relationship between blood biomarkers and biometric behavior in mature and older dogs, with the aim of establishing benchmark CCD data. The DOGMA Study is addressed in the companion Currents in One Health by Hunter et al, AJVR, November 2023.
Rectal tear repair using barbed suture in the horse
Authors: Kamm J. Lacy 
Published: September 2023

Abstract

OBJECTIVE
To describe the repair utilizing integral-anchor barbed suture in equine rectal tears.

ANIMALS
3 horses aged 3 to 10 years old with grade 3 to 4 rectal tears.

CLINICAL PRESENTATION
Grade 3 and 4 rectal tears were referred for surgical repair immediately after iatrogenic tearing or tearing during parturition. Integral-anchor barbed suture (Stratafix Symmetric PDS Plus, size 1, 18” CT-1) was placed using long-handled instruments or hand closure depending on the accessibility and visibility of the tear. Closure of grade 3 tears was performed using a continuous appositional pattern. A horizontal mattress pattern was performed in the grade 4 tear. No other surgical procedures were performed.

RESULTS
Two grade 3 tears were successfully repaired with no complications and discharged from the hospital. One grade 4 tear was successfully repaired; however, 4 days post-surgery partial dehiscence of the suture site occurred, and the horse was euthanized.

CLINICAL RELEVANCE
Grade 3 rectal tears were repaired successfully by using an integral-anchor barbed suture. No post-operative complications were reported. Blind hand suturing could be performed in cranial locations when the laceration could not be made visible. For grade 4 rectal tears, additional surgical procedures beyond barbed suture closure are needed.
An investigation of the discrepancy between set and actual temperature of neonatal incubators: concern for hypothermia and hyperthermia
Authors: Christensen Bruce W. , Erb Hollis N. 
Published: September 2023

Abstract

OBJECTIVE
To document any discordance between the set temperature and independently measured temperature of neonatal incubators in order to determine the potential of neonatal incubators to cause hypothermia or hyperthermia in neonatal animals.

SAMPLE
5 different veterinary neonatal incubators from 2 separate manufacturers.

METHODS
Internal temperatures of 5 incubators from 2 manufacturers were monitored with both internal and external monitoring devices to determine how much incubator temperatures might vary from what is reported on the incubator thermostat. The study was conducted on May 25, 2022.

RESULTS
Increases in temperature as measured by thermocouple and infrared sensors of > 2 °C were detected in 3 of the 5 (60%; 95% CI, 17% to 93%) tested incubators. Temperatures exceeded 41 °C at times, despite the incubator thermostat being set to 35 °C.

CLINICAL RELEVANCE
Neonatal puppies have a decreased capacity to thermoregulate and are susceptible to both hypothermia and hyperthermia if environmental temperatures are not kept within a proper range. Core temperatures below 35.0 °C lead to bradycardia, dyspnea, loss of suckle reflex, hypoglycemia, gastrointestinal ileus, and multiple organ failure; temperatures above 41.1 °C lead to pulmonary edema, petechial and ecchymotic hemorrhage in multiple organs, and death.
Deliberating in the Gray Zone: North Macedonia’s Hybrid Regime and Deliberative Democracy Exercise
Authors: Imeri Ardita Abazi 
Published: September 2023

Abstract
Deliberative polling has emerged as a promising method for promoting democratic reform and citizen engagement in various contexts, however, its potential and limitations in hybrid regimes, where democratic governance is challenged by a mix of democratic and authoritarian features, remain relatively unexplored. This paper focuses on the case of North Macedonia, as a country that has undergone significant political and societal transformation especially in the recent years. Despite efforts to promote democratic reforms, the country continues to face challenges in terms of ensuring democratic governance and citizen participation. In a hybrid regime, like North Macedonia’s, political leaders might not be inclined to value citizens’ input, and the media environment might not be free from influence, which limits access to varied and reliable sources of information. Civil society organizations may also encounter limitations on their operations, and institutional assistance may be insufficient. Additionally, the population’s diversity could make it difficult to reach and build trust with citizens. In this context, deliberative polling represents an opportunity to engage citizens in meaningful political dialogue and institutional reform. This paper examines the potential of deliberative polling as a tool for promoting governance in North Macedonia and highlights the challenges and limitations faced in this process.