bluuebunny/crossref_metadata_2025_split huggingface dataset:
The 1991 Handley Page Lecture — The engineering dimension in Europe
Authors: Levy J. C. 
Published: March 2023

It is customary to begin lectures of this kind with reference to the person after whom the lecture is named. I do so with particular relish on this occasion.This is because I spent most of my working life at The City University, formerly The Northampton Polytechnic, with which Sir Frederick Handley Page was closely associated throughout his working life.The results of a little archival work reveal that in June 1909 a class in aeronautics was arranged for the following session. As it turned out, the momentous event of 1910 was the appointment of a Mr Frederick Handley Page to be lecturer in aeronautics to attend for two evenings per week at £75 for the session.Not surprisingly the subject was a great success at the Northampton, and 81 years later at The City University, it still is.
Mercenary Punishment: Penal Logics in the Military Labour Market
Authors: Heinsen Johan 
Published: March 2023

AbstractThis article examines the entangled logics of corporal and carceral punishments of mercenary soldiers in eighteenth-century Denmark. Beginning with the story of a single man and his unfortunate trajectory through a sequence of punitive measures before his death as a prison workhouse inmate, the article looks at how punishments of soldiers communicated in multiple ways and were used to a variety of ends that were both typical and atypical within eighteenth-century society. It argues that soldiers experienced a breadth of both corporal and carceral punishments that were, in many cases, designed to limit otherness while communicating exemplarity along a fine-tuned spectrum of pain. The clearest example of this was running the gauntlet; a harrowing physical ordeal meted out by the offender's fellow soldiers. Turning to the carceral experiences often initiated by this ritual, it then examines how former mercenaries experienced convict labour differently from other occupational groups based on several factors. Their gender and occupational belonging meant they were funnelled towards specific penal institutions. Yet, their status as migrants and potential military labour meant they would often exit these institutions in specific ways. Whereas civilians often endured dishonouring punishments, ex-military convicts experienced punishments designed to inflict great pain without rendering them unfit for later military labour.
Effect of surgical intervention on serum insulin-like growth factor 1 in patients with obstructive sleep apnoea
Authors: Jaiswal A S , Valappil B V , Gupta Y , Sikka K , Thakar A , Verma H 
Published: March 2023

AbstractObjectiveTo evaluate the effect of surgical intervention on serum insulin-like growth factor 1 levels in patients with obstructive sleep apnoea.MethodsA prospective study was conducted in a tertiary care hospital of adult patients with obstructive sleep apnoea for whom continuous positive airway pressure therapy failed or was refused. All patients underwent polysomnography and serum insulin-like growth factor 1 evaluation pre-operatively and at three months post-operatively. The site of surgery was determined using Müller's manoeuvre and ApneaGraph AG 200.ResultsFifteen patients were included with a mean age of 38 years: 11 males and 4 females. The mean pre-operative Apnoea–Hypopnoea Index using polysomnography was 53.7 events per hour, and the mean post-operative Apnoea–Hypopnoea Index at three months was 15.3 events per hour (p = 0.0001). The mean pre-operative serum insulin-like growth factor 1 was 160.2 μg/l, while the mean post-operative value was 236.98 μg/l (p = 0.005).ConclusionIn adult patients with obstructive sleep apnoea for whom continuous positive airway pressure therapy fails, site-specific surgical intervention to treat the obstruction leads to an increase in serum insulin-like growth factor 1 levels.
Clinical outcomes of sinonasal inverted papilloma: a retrospective analysis of 139 cases
Authors: Yeom S , Lee D H , Lim S C 
Published: March 2023

AbstractObjectivesSinonasal inverted papilloma has a high tendency for recurrence, local bone destruction and risk of malignant transformation. Therefore, complete resection of the tumour is required, and close follow up is essential. This article describes the clinical outcomes, recurrence rate and malignant transformation rate of sinonasal inverted papilloma.MethodsIn this study, 139 patients diagnosed with sinonasal inverted papilloma in our hospital from December 2010 to May 2022 were retrospectively analysed. All patients underwent endoscopic surgery.ResultsSinonasal inverted papilloma occurred more often in males than in females. The mean age of patients with sinonasal inverted papilloma was 67.3 ± 5.7 years at diagnosis. The most prevalent site of origin was the maxillary sinus (50.4 per cent). The recurrence rate was 5.75 per cent, and the malignant transformation rate was 6.5 per cent.ConclusionAll patients in this study underwent endoscopic surgery. Meticulous resection and regular long-term follow ups are crucial to reducing sinonasal inverted papilloma recurrence after surgery.
In defence of God making stuff up: a reply to Ward
Authors: Gould Paul M. 
Published: March 2023

AbstractThomas Ward explicates and defends a version of divine exemplarism called Containment Exemplarism to make good on the claim that God is a ‘totally original artist’. According to Containment Exemplarism, (i) God ex nihilo creates according to divine ideas, (ii) divine ideas are about an aspect or part of God, and (iii) God has the ideas he has by knowing himself. Containment Exemplarism, we are told, secures the rationality and creativity of the divine creative act. I argue, first, that Ward's God is not a totally original artist since, on Containment Exemplarism, God does not act creatively in creating. Theistic Activism, the view that God makes up the ideas he has, can secure the creativity of the divine creative act. I argue, second, that Ward's argument against the rationality of God making stuff up fails. Thus, there is one version of divine exemplarism that satisfies key desiderata for divine creation.
Adversarial agent-learning for cybersecurity: a comparison of algorithms
Authors: Shashkov Alexander , Hemberg Erik , Tulla Miguel , O’Reilly Una-May 
Published: March 2023

Abstract
We investigate artificial intelligence and machine learning methods for optimizing the adversarial behavior of agents in cybersecurity simulations. Our cybersecurity simulations integrate the modeling of agents launching Advanced Persistent Threats (APTs) with the modeling of agents using detection and mitigation mechanisms against APTs. This simulates the phenomenon of how attacks and defenses coevolve. The simulations and machine learning are used to search for optimal agent behaviors. The central question is: under what circumstances, is one training method more advantageous than another? We adapt and compare a variety of deep reinforcement learning (DRL), evolutionary strategies (ES) and Monte Carlo Tree Search methods within Connect 4, a baseline game environment, and on both a simulation supporting a simple APT threat model, SNAPT, as well as CyberBattleSim, an open-source cybersecurity simulation. Our results show that when attackers are trained by DRL and ES algorithms, as well as when they are trained with both algorithms being used in alternation, they are able to effectively choose complex exploits that thwart a defense. The algorithm that combines DRL and ES achieves the best comparative performance when attackers and defenders are simultaneously trained, rather than when each is trained against its non-learning counterpart.
Epidemiology of invasive meningococcal disease worldwide from 2010–2019: a literature review
Authors: Pardo de Santayana Carmen , Tin Tin Htar Myint , Findlow Jamie , Balmer Paul 
Published: March 2023

Abstract
The epidemiology of invasive meningococcal disease (IMD) is unpredictable, varies by region and age group and continuously evolves. This review aimed to describe trends in the incidence of IMD and serogroup distribution by age group and global region over time. Data were extracted from 90 subnational, national and multinational grey literature surveillance reports and 22 published articles related to the burden of IMD from 2010 to 2019 in 77 countries. The global incidence of IMD was generally low, with substantial variability between regions in circulating disease-causing serogroups. The highest incidence was usually observed in infants, generally followed by young children and adolescents/young adults, as well as older adults in some countries. Globally, serogroup B was a predominant cause of IMD in most countries. Additionally, there was a notable increase in the number of IMD cases caused by serogroups W and Y from 2010 to 2019 in several regions, highlighting the unpredictable and dynamic nature of the disease. Overall, serogroups A, B, C, W and Y were responsible for the vast majority of IMD cases, despite the availability of vaccines to prevent disease due to these serogroups.
Life stress influences the relationship between sex hormone fluctuation and affective symptoms in peripubertal female adolescents
Authors: Andersen Elizabeth , Klusmann Hannah , Eisenlohr-Moul Tory , Baresich Kayla , Girdler Susan 
Published: March 2023

AbstractFemale adolescents have a greatly increased risk of depression starting at puberty, which continues throughout the reproductive lifespan. Sex hormone fluctuation has been highlighted as a key proximal precipitating factor in the development of mood disorders tied to reproductive events; however, hormone-induced affective state change is poorly understood in the pubertal transition. The present study investigated the impact of recent stressful life events on the relationship between sex hormone change and affective symptoms in peripubertal female participants. Thirty-five peripubertal participants (ages 11–14, premenarchal, or within 1 year of menarche) completed an assessment of stressful life events, and provided weekly salivary hormone collections [estrone, testosterone, dehydroepiandrosterone (DHEA)] and mood assessments for 8 weeks. Linear mixed models tested whether stressful life events provided a context in which within-person changes in hormones predicted weekly affective symptoms. Results indicated that exposure to stressful life events proximal to the pubertal transition influenced the directional effects of hormone change on affective symptoms. Specifically, greater affective symptoms were associated with increases in hormones in a high stress context and decreases in hormones in a low stress context. These findings provide support for stress-related hormone sensitivity as a diathesis for precipitating affective symptoms in the presence of pronounced peripubertal hormone flux.
Evidence-Based Policy Making during the Coronavirus Disease 2019 Pandemic: A Systematic Review
Authors: Matsuda Shinpei , Yoshimura Hitoshi 
Published: March 2023

AbstractIntroduction:The aim of this systematic review was to collect evidence and recommendations for the applicability of the concept of evidence-based policy making (EBPM) during the coronavirus disease 2019 (COVID-19) pandemic and to discuss the implementation of this concept from a medical science perspective.Methods:This study was performed according to the guidelines, checklist, and flow diagram of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020. An electronic literature search was conducted on September 20, 2022 using PubMed, Web of Science, Cochrane Library, and CINAHL databases with the following search terms: “evidence based policy making” and “infectious disease.” Study eligibility assessment was performed based on the flow diagram of PRISMA 2020, and risk of bias assessment was performed using The Critical Appraisal Skills Program.Results:Eleven eligible articles were included in this review and divided into three groups as follows: early, middle, and late stages of the COVID-19 pandemic. Basics of COVID-19 control were suggested in the early stage. The articles published in the middle stage discussed the importance of the collection and analysis of evidence of COVID-19 from around the world for the establishment of EBPM in the COVID-19 pandemic. The articles published in the late stage discussed the collection of large amounts of high-quality data and the development of methods to analyze them, as well as emerging issues related to the COVID-19 pandemic.Conclusions:This study revealed that the concept of EBPM applicable to emerging infectious disease pandemics changed between the early, middle, and late stages of the pandemic. The concept of EBPM will play an important role in medicine in the future.
Using Machine Learning to Cut the Cost of Dynamical Downscaling
Authors: Hobeichi Sanaa , Nishant Nidhi , Shao Yawen , Abramowitz Gab , Pitman Andy , Sherwood Steve , Bishop Craig , Green Samuel 
Published: March 2023

AbstractGlobal climate models (GCMs) are commonly downscaled to understand future local climate change. The high computational cost of regional climate models (RCMs) limits how many GCMs can be dynamically downscaled, restricting uncertainty assessment. While statistical downscaling is cheaper, its validity in a changing climate is unclear. We combine these approaches to build an emulator leveraging the merits of dynamical and statistical downscaling. A machine learning model is developed for each coarse grid cell to predict fine grid variables, using coarse‐scale climate predictors with fine grid land characteristics. Two RCM emulators, one Multilayer Perceptron (MLP) and one Multiple Linear Regression error‐reduced with Random Forest (MLR‐RF), are developed to downscale daily evapotranspiration from 12.5 km (coarse‐scale) to 1.5 km (fine‐scale). Out‐of‐sample tests for the MLP and MLR‐RF achieve Kling‐Gupta‐Efficiency of 0.86 and 0.83, correlation of 0.89 and 0.86, and coefficient of determination (R2) of 0.78 and 0.75, with a relative bias of −6% to 5% and −5% to 4%, respectively. Using histogram match for spatial efficiency, both emulators achieve a median score of ∼0.77. This is generally better than a common statistical downscaling method in a range of metrics. Additionally, through “spatial transitivity,” we can downscale GCMs for new regions at negligible cost and only minor performance loss. The framework offers a cheap and quick way to downscale large ensembles of GCMs. This could enable high‐resolution climate projections from a larger number of global models, enabling uncertainty quantification, and so better support for resilience and adaptation planning.
Decadal Changes in Ventilation and Anthropogenic Carbon in the Nordic Seas
Authors: Jeansson Emil , Tanhua Toste , Olsen Are , Smethie William M. , Rajasakaren Balamuralli , Ólafsdóttir Sólveig R. , Ólafsson Jón 
Published: March 2023

AbstractWe evaluate the decadal evolution of ventilation and anthropogenic carbon (Cant) in the Nordic Seas between 1982 and the 2010s. Ventilation changes on decadal timescale are identified by evaluating decadal changes in mean ages and apparent oxygen utilization in each of the four main basins of the Nordic Seas (the Greenland and Iceland Seas, and the Norwegian and Lofoten Basins). The ages are derived from the transient time distribution approach, based on the transient tracers chlorofluorocarbon‐12 (CFC‐12) and sulfur hexafluoride (SF6). The different decades show different phases in ventilation, with the 2000s being overall better ventilated than the 1990s in all basins. For the Greenland Sea, we also show that the 2010s are better ventilated than the 2000s, with a clear shift in hydrographic properties. The evolution of concentrations and inventory of Cant is linked to the ventilation state. The deep waters get progressively older over the analyzed period, which is connected to the increased fraction of deep water from the Arctic Ocean.
Regime‐Specific Cloud Vertical Overlap Characteristics From Radar and Lidar Observations at the ARM Sites
Authors: Balmes Kelly A. , Sedlar Joseph , Riihimaki Laura D. , Olson Joseph B. , Turner David D. , Lantz Kathleen 
Published: March 2023

AbstractClimate and numerical weather prediction models require assumptions to represent the vertical distribution of subgrid‐scale clouds, which have radiative transfer implications. In this study, nearly 25 years of ground‐based radar and lidar observations of vertical cloud profiles at the Atmospheric Radiation Measurement Program (ARM) Southern Great Plains (SGP) site are utilized to derive cloud vertical overlap characteristics from the Cloud Type (CLDTYPE) data product. The cloud vertical overlap characteristics are further separated by cloud regime by considering seven cloud types (i.e., low cloud, congestus, deep convection, altocumulus, altostratus, cirrostratus, and cirrus) as well as periods of shallow cumulus. The decorrelation length scale (i.e., exponential transition from maximum to random overlap with layer separation) is found to vary by cloud regime, ranging between 0.04 km for cirrostratus paired with cirrus to 4.58 km for low cloud paired with cirrus at SGP. Cloud vertical overlap characteristics are also considered for other ARM sites including the Tropical Western Pacific (TWP), North Slope of Alaska (NSA), and Eastern North Atlantic (ENA) sites among other shorter term ARM deployments globally. The decorrelation length scale ranged globally from 1.03 km in the Arctic Ocean to 3.06 km in Manacapuru, Brazil. Globally, the decorrelation length scale by cloud regime exhibited similarities (e.g., for cirrus paired with cirrus) and differences (e.g., congestus paired with cirrus). The results could help inform development of cloud vertical overlap assumptions within operational numerical weather prediction models and potentially improve prediction of radiative fluxes for weather, climate, and renewable energy forecasting.
Formation Mechanisms and Source Apportionments of Nitrate Aerosols in a Megacity of Eastern China Based On Multiple Isotope Observations
Authors: Fan Mei‐Yi , Zhang Wenqi , Zhang Yan‐Lin , Li Jianghanyang , Fang Huan , Cao Fang , Yan Ming , Hong Yihang , Guo Hai , Michalski Greg 
Published: March 2023

AbstractInorganic nitrate (NO3−) is a crucial component of fine particulate matter (PM2.5) in haze events in China. Understanding the formation mechanisms of nitrate and the sources of NOx was critical to control the air pollution. In this study, measurements of multiple isotope compositions of nitrate (δ18O‐NO3−, δ17O‐NO3−, and δ15N‐NO3−) in PM2.5 were conducted in Hangzhou from 9 October 2015 to 24 August 2016. Our results showed that oxygen anomaly of nitrate (Δ17O‐NO3−: 20.0‰–37.9‰) and nitrogen isotope of nitrate (δ15N‐NO3−: −2.9‰ to 18.1‰) values were higher in winter and lower in summer. Based on Δ17O‐NO3− observation and a Bayesian model, NO3 radical chemistry was found to dominate the nitrate formation in winter, while photochemical reaction (NO2 + OH) was the main pathway in summer. After considering the nitrogen isotopic fractionation in the NOx(g)‐NO3−(p) conversion, the average contributions of coal combustion, vehicle exhausts, biomass burning, and soil emission were 50% ± 9%, 19% ± 12%, 26% ± 15%, and 5% ± 4%, respectively, to nitrate aerosols during the whole sampling period. Coal combustion was the most important nitrate source in Hangzhou, especially in winter (∼56%). The contribution of soil emission increased significantly in summer due to active soil microbial processes under high temperature environment.
Interactions Between Depositional Regime and Climate Proxies in the Northern South China Sea Since the Last Glacial Maximum
Authors: Wang Xuesong , Zhong Yi , Clift Peter D. , Feng Yingci , Wilson David J. , Kaboth‐Bahr Stefanie , Bahr André , Gong Xun , Zhao Debo , Chen Zhong , Zhang Yanan , Tian Yuhang , Liu Yuxing , Liu Xiaoyu , Liu Jiabo , Xia Wenyue , Yang Huihui , Cao Wei , Liu Qingsong 
Published: March 2023

AbstractSedimentary deposits from the northern South China Sea (SCS) can provide important constraints on past changes in ocean currents and the East Asian summer monsoon (EASM) in this region. However, the interpretation of such records spanning the last deglaciation is complicated because sea‐level change may also have influenced the depositional processes and patterns. Here, we present new records of grain size, clay mineralogy, and magnetic mineralogy spanning the past 24 kyr from both shallow and deep‐water sediment cores in the northern SCS. Our multi‐proxy comparison among multiple cores helps constrain the influence of sea‐level change, providing confidence in interpreting the regional climate‐forced signals. After accounting for the influence of sea‐level change, we find that these multi‐proxy records reflect a combination of changes in (a) the strength of the North Pacific Intermediate Water inflow, (b) the EASM strength, and (c) the Kuroshio Current extent. Overall, this study provides new insights into the roles of varying terrestrial weathering and oceanographic processes in controlling the depositional record on the northern SCS margin in response to climate and sea‐level fluctuations.
High Energy Solar Particle Events and Their Relationship to Associated Flare, CME and GLE Parameters
Authors: Waterfall C. O. G. , Dalla S. , Raukunen O. , Heynderickx D. , Jiggens P. , Vainio R. 
Published: March 2023

AbstractLarge solar eruptive events, including solar flares and coronal mass ejections (CMEs), can lead to solar energetic particle (SEP) events. During these events, protons are accelerated up to several GeV and pose numerous space weather risks. These risks include, but are not limited to, radiation hazards to astronauts and disruption to satellites and electronics. The highest energy SEPs are capable of reaching Earth on timescales of minutes and can be detected in ground level enhancements (GLEs). Understanding and analyzing these events is critical to future forecasting models. However, the availability of high energy SEP data sets is limited, especially that which covers multiple solar cycles. The majority of analysis of SEP events considers data at energies <100 MeV. In this work, we use a newly calibrated data set using data from Geostationary Operational Environmental Satellite‐high energy proton and alpha detector between 1984 and 2017. Analysis of the SEP events in this time period over three high energy channels is performed, and SEP properties are compared to flare and CME parameters. In addition, neutron monitor (NM) observations are examined for the relevant GLE events. We find that correlations between SEP peak intensity and the CME speed are much weaker than for lower SEP energies. Correlations with flare intensity are broadly similar or weaker. Strong correlations are seen between >300 MeV data and GLE properties from NM data. The results of our work can be utilized in future forecasting models for both high energy SEP and GLE events.