bluuebunny/crossref_metadata_2025_split huggingface dataset:
No Warm-Phase Invigoration of Convection Detected during GoAmazon
Authors: Öktem Rusen , Romps David M. , Varble Adam C. 
Published: April 2023

Abstract
It has been proposed that air pollution increases the updraft speeds of warm-phase convective clouds by reducing their supersaturation and, thereby, enhancing their buoyancy. Observations from the GoAmazon field campaign, sampled using subjective criteria, have been offered as evidence for this warm-phase invigoration. Here, we reexamine those GoAmazon observations using objective sampling criteria and find no indication that air pollution increases warm-phase updraft speeds. In addition, the observations yield no statistically significant relationship between aerosol concentrations and either moist-convective vertical velocity or reflectivity in either the lower or upper troposphere.
Network Structure of Atmospheric Perturbations
Authors: Ishibashi Toshiyuki 
Published: April 2023

Abstract
Accurate atmospheric-state analysis is essential for understanding and prediction of the atmosphere and is a difficult scientific problem due to the chaotic nature of the atmosphere; namely, small atmospheric perturbations (APs) grow rapidly in nonlinear processes. The key to atmospheric-state analysis is knowing the structure of the APs. We analyzed the AP structure in terms of network theory using a 192-member AP ensemble. The AP ensemble was generated by an ensemble of variational data assimilation (DA) with the perturbed observation method using the operational numerical weather prediction system at the Japan Meteorological Agency. The generated APs captured flow-dependent AP structures corresponding to atmospheric normal modes, and their use in DA improved accuracy of atmospheric-state predictions. These show the usefulness of the APs. The network property of the APs are as follows. The atmosphere has a small average network distance compared with the square root of the number of nodes, and a large clustering coefficient (about 0.6). These show that the APs have small-world network properties. The degree distribution of APs shows the heavy-tailed structure. These three properties of APs are common to various complex networks in other systems. Hubs in the AP network correspond to atmospheric disturbances. The network community detection using network modularity shows about 18 communities with 0.8 modularity. These basic network properties of APs represent efficient information exchange in the atmosphere, which provides a complementary atmospheric picture to its traditional physical picture based on fluid dynamics and thermodynamics, and would be basic information for atmospheric sciences and extension of application target of the network theory.

Significance Statement
The purpose of this paper is to analyze properties of atmospheric perturbations using the network theory and an accurate ensemble of the atmospheric perturbations. This is important for atmospheric-state estimation and forecasting because the atmosphere is chaotic and small perturbations grow rapidly. Our results show that the atmosphere has a small average network distance and a large clustering coefficient, which are the properties of a small-world network, and a heavy-tailed degree distribution. These three properties of atmospheric perturbations are common to various complex networks in other systems.
Influence of contrast agent on artificial intelligence-based CT low attenuation volume percentage measurement
Authors: Wiedbrauck Damian , Karczewski Maciej , Schoenberg Stefan O , Fink Christian , Kayed Hany 
Published: April 2023

Background Low attenuation volume percentage (LAV%) has been identified as a quantitative imaging biomarker for emphysema with good correlation with spirometry. The influence of intravenous contrast agent on LAV% and its correlation with spirometry is not well known. Purpose To evaluate the influence of intravenous contrast agent on artificial intelligence (AI)-based LAV% in correlation with spirometric Tiffeneau-Pinelli Index (TI). Material and Methods In a retrospective study, two groups of 47 patients (mean age 68.04 ± 12.64 and 67.89 ± 11.54 years) with either non-enhanced chest computed tomography (CT) or contrast-enhanced CT were compared. Using an AI-based software, LAV% was quantified using a threshold <−950 HU. TI was calculated from spirometry and pathologic airway obstruction was considered with a TI <70. The effect of contrast agent on LAV% and the relationship between TI and LAV% was analyzed. Correlation coefficients between TI and LAV% were compared for both groups. Results Patients with non-enhanced CT had a mean LAV% of 9.07 ± 7.53. Of them, 22 patients had a TI <70% and 25 patients a TI ≥70%. Patients with contrast-enhanced CT had a mean LAV% of 6.54 ± 4.62. Of them, 20 patients had a TI <70% and 27 patients had a TI ≥70%. Contrast agent did not show a major effect on LAV% ( P = 0.099) and the relationship between TI and LAV% ( P = 0.88). In both groups, a significant correlation between TI and LAV% was found (ρ = −0.317 for non-enhanced CT; ρ = −0.514 for contrast-enhanced CT). Difference between correlation coefficients was insignificant. Conclusion Our findings suggest that contrast agent does not influence LAV% nor its correlation with TI.
Sexuality and ageing: A mixed methods explorative study of older adult’s experiences, attitudes, and support needs
Authors: Portellos Amelia , Lynch Claire , Joosten Annette 
Published: April 2023

Introduction: Sexuality contributes to health and wellbeing, but it is often overlooked as an important occupation for older adults. Older adult studies focus on decreased participation and functioning in sexual acts. This study aimed to obtain perspectives and explore understandings and experiences of sexuality and of support needs, for typically ageing adults. Method: Seventy-five older adults aged 60 years and older participated in the online cross-sectional survey. Participants were primarily from Australia, the United States, and the United Kingdom. Closed questions were analyzed using descriptive and inferential statistics, and reflexive thematic analysis was used for open questions. Results: Throughout the ageing process, older adults continued to value their sexuality, expression, desire, and identity, though meanings and participation changed. Changes and challenges were overcome through openness, exploration, curiosity, valued relationships, and adaptations to ways of doing. Older adults identified being dissatisfied with current sexual health supports, resources, and services. Conclusion: Healthcare professionals need to develop intervention knowledge to address diverse needs, and better support older adults in sexuality through open discussion, addressing psychological, social, and health concerns as part of everyday practice. The development of standardized assessments and resources with consumer collaboration will ensure resources address multifaceted components of sexuality, and older adults’ needs.
Melatonin intake before intradialytic exercise reverses oxidative stress and improves antioxidant status in hemodialysis patients
Authors: Marzougui Houssem , Turki Mouna , Ben Dhia Imen , Maaloul Rami , Chaker Hanen , Makhlouf Rihab , Agrebi Ikram , Kammoun Khawla , Jamoussi Kamel , Ayadi Fatma , Ben Hmida Mohamed , Hammouda Omar 
Published: April 2023

Purpose: The present study aimed to investigate for the first time the effects of melatonin (MEL) intake on oxidative stress and cellular damage during intradialytic exercise (IEX). Methods: Thirteen hemodialysis (HD) patients volunteered to participate in the current randomized crossover trial. Participants performed four HD sessions in four different conditions: (Exercise (EX)-MEL), (EX-Placebo (PLA)), (Control (C)-MEL), and (C-PLA). 3 mg of MEL or PLA were taken 60 min before starting exercise, or at the equivalent time in the C conditions. Blood samples were taken before HD (T0), immediately after the end of IEX (T1), 60 min after IEX (T2), or at the corresponding times in the C conditions to measure free radicals damage, antioxidant biomarkers, as well as biomarkers of muscle and liver damage. Results: Malondialdehyde and Advanced Oxidation Protein Products decreased in (C-MEL) ( p < 0.05, d = 2.19; p < 0.01, d = 0.99, respectively) at T2 compared to T0. Catalase and total thiol levels increased in (C-MEL) ( p < 0.01, d = 1.51; p < 0.01, d = 1.56, respectively) and in (EX-MEL) ( p = 0.01, d = 1.28; p < 0.01, d = 1.52, respectively) at T1 compared to T0. Total bilirubin levels increased in (EX-MEL) and (C-MEL) at T2 compared to T0 ( p < 0.001, d = 2.77; p < 0.001, d = 1.36, respectively), but only at T2 compared to T1 in (EX-MEL) ( p < 0.001, d = 1.67). In all conditions, uric acid levels decreased at T1 compared to T0 and at T2 compared to T1, while biomarkers of muscle and liver damage remained unchanged. Conclusion: This pilot study is the first to show that MEL ingestion, alone or combined with IEX, could improve oxidant-antioxidant balance during HD.
Reduced circulating Tregs and positive pANCA were robustly associated with the occurrence of antiphospholipid syndrome in patients with systemic lupus erythematosus
Authors: Wang Jia , Guo Hong-Xia , Cheng Ting , Shi Lei , Zhang Sheng-Xiao , Li Xiao-Feng 
Published: April 2023

Background Systemic lupus erythematosus (SLE) is a typical chronic immune disorder with clinical heterogeneity. The systemic abnormal immune response not only challenges the diagnosis and treatment of the disease itself but also the secondary antiphospholipid syndrome (APS), characterized by recurrent arterial or venous thrombosis, recurrent spontaneous abortion, or stillbirth. Clinical interest has primarily focused on primary APS’s pathological and clinical features. However, differences in clinical features and laboratory indicators between SLE with or without APS are still lacking, especially differences between circulating lymphocytes, which are critical in the pathogenesis of SLE and its complications. Methods In this retrospective study, we collected and analyzed clinical characteristics, general laboratory indicators, immunological indicators, and circulating lymphocyte subsets of SLE with or without APS. Results Systemic lupus erythematosus with APS (SLE-APS) had elevated SLEDAI scores, hospitalization costs and time, and frequencies of central nervous system symptoms and spontaneous abortion compared with those without APS. SLE-APS had higher positive anti-Cardiolipin antibodies, anti-β2 Glycoprotein 1 antibodies, and perinuclear antineutrophil cytoplasmic antibody (pANCA) than none-APS patients. Compared with healthy controls (HCs), the circulating lymphocyte subsets were altered to some extent in all patients, especially in patients with SLE-APS. Reduced Tregs and positive pANCA were independent risk factors for SLE secondary APS. Conclusion The present study revealed a robust association between APS secondary to SLE and reduced Tregs and positive pANCA, which provides essential information regarding the diagnosis and therapeutic possibilities of APS secondary to SLE.
Evaluation of Surgical Clinic Nurses’ Knowledge Levels About Palliative Surgery
Authors: Doğan Runida , Doğan Aysel , Karasu Fatma , Bağci Nazlıcan 
Published: April 2023

Background Currently, palliative care plays an important role in increasingly aging populations and their long-term care needs. Surgical palliative care is important for improving quality of life. This study aimed to determine the knowledge level of nurses working in surgical clinics about palliative surgery. Method This research was conducted as a descriptive study. We included 182 nurses working in surgical clinics who agreed to participate and met the inclusion criteria for participation in the study. The Personal Information and Palliative Surgery Information Forms were used to collect data. Data were collected between November 30, and December 15, 2022. The analysis of the data obtained was performed using the Statistical Program in Social Sciences (SPSS), Version 25. The level of significance was set at P < .05. Results Nurses referred to palliative care as end-of-life care, 73.1% did not care for palliative care patients, and 84.6% did not receive training in palliative care. Surgical clinic nurses were found to have “moderate knowledge about palliative surgery. A statistically significant difference was found between the average palliative surgery knowledge of surgical clinic nurses and those trained in education and palliative care ( P < .05). Conclusions The results of the study showed that surgical clinic nurses had moderate knowledge about palliative surgery. Moreover, the nurses who have received training in palliative care and had high level of education exhibited a higher level of knowledge.
Parental separation and school dropout in adolescence
Authors: Karhina Kateryna , Bøe Tormod , Hysing Mari , Askeland Kristin G. , Nilsen Sondre A. 
Published: April 2023

Aims: To document the association between parental separation and school dropout in adolescence and to examine the factors that may potentially account for this association. Methods: Data stem from the large youth@hordaland study that was linked to the Norwegian National Educational Database to obtain objective measures of educational outcomes and disposable income ( N = 8323). Logistic regression analysis was used to investigate the association between parental separation and school dropout. A Fairlie post-regression decomposition was used to examine the influence of parental education, household income, health complaints, family cohesion, and peer problems in explaining the association between parental separation and school dropout. Results: Parental separation was associated with a higher odds ratio (OR) of school dropout in crude and adjusted (adjusted odds ratio (AOR)) analyses (OR=2.16, 95% confidence interval (CI) =1.90–2.45; AOR = 1.72, 95% CI = 1.50–2.00). About 31% of the higher odds of school dropout among adolescents with separated parents was explained by the covariates. The decomposition analysis suggested that parental education (43%) and disposable income (20%) accounted for most of the explained differences in school dropout. Conclusions: Adolescents with separated parents are at higher risk for not completing secondary education. Parental education and disposable income accounted for most of the explained differences in school dropout between the groups. Still, the majority of the difference in school dropout remained unaccounted for, indicating that the link between parental separation and school dropout is complex and likely influenced by multiple factors.
Endovascular Treatment for Isolated Infected Iliac Artery Aneurysms
Authors: Sun Hongze , Qin Weidong , Shao Wenchong , Zhou Haimeng , Wang Xiaowei , Jiang Jianjun , Ding Xiangjiu 
Published: April 2023

Purpose: Isolated infected iliac artery aneurysms (IIIAAs) are extremely rare, life-threatening, and intractable. This study aimed to evaluate the outcomes of endovascular treatment in patients with IIIAAs. Methods: A retrospective study was conducted for all patients who underwent endovascular treatment for IIIAAs between June 2012 and June 2022 in 3 hospitals. The clinical data and follow-up outcomes were reviewed and assessed. Results: Fifteen patients were included in this study. The median age was 69 years, 12 patients (80%) were men, and 8 (53%) had hypertension. Most of the patients presented with abdominal or lumbar pain (87%) and fever (60%). The offending pathogen was identified in 11 patients (73%). Fifteen patients had a total of 16 IIIAAs, with 12 (75%) involving the common iliac artery. The immediate technical success rate was 100%, and the 30-day mortality was 7%. Infection-related complications occurred in 2 patients (13%) during hospitalization who were treated by open surgery at a later stage. The median follow-up was 23 months (range: 6–80 months, mean: 32 ± 25 months). Aneurysm recurrence was identified in one patient (7%) 5 months after endovascular repair. It was managed by endovascular stent-graft repair with percutaneous catheter drainage. No patients died during the follow-up period. Conclusion: Endovascular treatment is feasible, safe, and effective for patients with IIIAAs, achieving acceptable clinical outcomes. Infection surveillance with essential reintervention should be considered for potential infection-related complications. Clinical Impact This study first reported that 15 patients underwent endovascular treatment for primary isolated infected iliac artery aneurysms (IIIAAs). It showed a good early and midterm outcomes. This is the first and largest multi-center study and the first literature review of IIIAAs. It provides an evidence that endovascular treatment is feasible, safe, and effective to treat IIIAAs. It suggests endovascular treatment is a promising alternative or a bridge to conventional open surgery for IIIAAs. This may promote endovascular therapy in the management of IIIAAs. It would help clinicians to make an appropriate treatment choice for IIIAAs.
Anxiolytic and Antidepressant Potential of Methanolic Extract of Neurada procumbens Linn. in Mice
Authors: Khalid Ahmed Awais , Jabeen Qaiser , Javaid Faraza 
Published: April 2023

Neurada procumbens Linn. possesses a wide range of phytochemical and bioactive entities such as flavonoids and polyphenols that decrease the oxidative stress and enhance synaptic plasticity, resulting in accelerated healing processes. Almost all parts of the plant have been used in the traditional system of medicine for various disorders including its use as an anticonvulsant, sexual tonic, and anti-rheumatic agent. This study is designed to evaluate the anxiolytic and antidepressant activities of the methanolic crude extract of N. procumbens (Np.Cr) based on its use in traditional medicine and presence of the phytochemical constituents. Aqueous methanolic extract of Np.Cr was prepared under reduced pressure using rotary evaporator, and different chemical constituents were identified by phytochemical screening. Light/dark exploration, elevated plus maze (EPM), and hole board tests were used to assess the anxiolytic activity, while forced swim and tail suspension tests were used to assess the antidepressant potential of the crude extract. Treatment groups treated individually with 3 different doses; i.e., 50, 100, and 200 mg/kg of Np.Cr, showed a dose-dependent increase in time spent in light compartment and in open arms as well as increased number of head poking by the experimental animals. Np.Cr showed significant antidepressant potential ( P < .05) as evident from marked decrease in behavioral despair. Findings of the present study assure that N. procumbens possess significant anxiolytic and antidepressant potential with the demands of further investigations to identify the active compound(s) responsible for these pharmacological effects.
“I liked just that it was a communal thing”: Feasibility and acceptability of engaging with transgender and gender-diverse persons in a digital photovoice research study on commercial cigarette smoking risk and protective factors
Authors: Hanby Elaine , Gazarian Priscilla K. , Potter Jennifer , Jones Raquel , Elhassan Noon , Tan Andy S.L. 
Published: April 2023

Background Commercial cigarette smoking is the leading modifiable risk factor for more than 16 types of cancer. Over one-third (35.5%) of transgender and gender-diverse (TGD) adults smoke cigarettes compared to 14.9% of cisgender adults. The objective of this paper is to describe the feasibility of enrolling and engaging with TGD persons in a digital photovoice study to examine smoking risk and protective factors through real-world experiences (Project SPRING). Methods The study comprised a purposeful sample of 47 TGD adults aged ≥18 years who currently smoke and live in the United States (March 2019–April 2020). They participated in three weeks of digital photovoice data collection using Facebook and Instagram closed groups. A subsample participated in focus groups to explore smoking risks and protective factors in greater depth. We summarized the enrollment strategies and accrual rates, participant engagement (posts, comments, and reactions) during the photovoice data collection to assess study feasibility, and respondent feedback on acceptability and likability during and after the study. Results Participants were recruited via Facebook/Instagram advertising ( n = 33) and via Craigslist/word-of-mouth ( n = 14). Costs ranged from $29 via Craigslist/word-of-mouth to $68 per recruited participant via Facebook/Instagram advertising. On average, participants posted 17 pictures of smoking risks/protective factors, commented 15 times on others’ posts, and had 30 reactions within their group over 21 days. Participants’ rating of the acceptability and likability of the study were positive based on closed- and open-ended feedback. Conclusion The findings of this report will inform future research to engage with TGD community-engaged research to develop culturally tailored interventions to reduce smoking prevalence among TGD individuals.
Primary and Secondary Risk Factors Associated With Concussion Symptom Clusters in Collegiate Athletes: Results From the NCAA-DoD Grand Alliance CARE Consortium
Authors: Nolan Kate E. , Caccese Jaclyn B. , Kontos Anthony P. , Buckley Thomas A. , Garcia Gian-Gabriel P. , Port Nicholas , Broglio Steven P. , McAllister Thomas W. , McCrea Michael , Pasquina Paul F. , Hayes Jasmeet P. ,   on behalf of the CARE Consortium Investigators
Published: April 2023

Background: There is a broad and diverse range of symptoms after a concussion, from irritability to nausea. This heterogeneity of symptoms is a challenge for clinicians managing the different presentations among injuries. Prior research has investigated the structure of postconcussive symptoms to determine if they can be grouped into clusters of related symptoms. Purpose/Hypothesis: The purpose of this study was to identify symptom clusters during the acute phase after a sports-related concussion using exploratory factor analysis and to understand the relationship between risk factors for postconcussion symptoms (ie, demographics, injury characteristics, mental health, and sleep qualities) and different symptom clusters. We hypothesized that certain factors would be predictive of specific symptom clusters. Study Design: Cross-sectional study; Level of evidence, 3. Methods: Collegiate athletes (N = 1104) from the Concussion, Assessment, Research, and Education (CARE) Consortium completed the Sport Concussion Assessment Tool–Third Edition symptom assessment tool 24 to 48 hours after concussion. Exploratory factor analysis was conducted on the symptom evaluation to determine symptom clusters 24 to 48 hours after concussion. Regression analysis was used to examine the effects of pre- and postinjury characteristics. Results: Exploratory factor analysis revealed a 4-cluster structure for acute postconcussive symptoms that explained 62% of the variance in symptom reporting: vestibular-cognitive, migrainous, cognitive fatigue, and affective. Delayed reporting, less sleep before assessment, female sex, and being hurt outside of competition (during practice/training) was correlated with increased symptoms for 4 symptom clusters. Depression predicted higher vestibular-cognitive and affective symptoms. Amnesia was correlated with higher vestibular-cognitive and migrainous symptoms, whereas migraine history was associated with more migrainous and affective symptoms. Conclusion: Symptoms can be grouped into 1 of 4 distinct clusters. Certain variables were associated with increased symptoms across multiple clusters and may be indicative of greater injury severity. Other factors (ie, migraine history, depression, amnesia) were associated with a more specific symptom presentation and may be mechanistically related to concussion outcomes and biological markers.