bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mucoid Degeneration of the Anterior Cruciate Ligament: Characteristics and Conservative Management
Authors: Luo Jianzhou , Zhou Minmin , Luo Xiaozhen , Luo Peng , Yang Zili , Li Ruifang , Duan Chunguang , Feng Xujiao , Wu Tailin 
Published: February 2023

AbstractClinical and radiographic characteristics of mucoid degeneration of the anterior cruciate ligament (MD-ACL) were poorly documented in previous literature. And the optimal management strategy for MD-ACL remains unclear. Here, we summarized the characteristics associated with MD-ACL, and evaluated the clinical outcome of conservative management to MD-ACL.A total of 18 knees in 18 patients diagnosed with MD-ACL were collected and reviewed retrospectively. Sixteen patients underwent conservative management and two patients underwent arthroscopic surgery. Baseline demographic, clinical data, and pathologic changes of knee in magnetic resonance imaging (MRI) were recorded. Clinical outcome was evaluated with Visual Analogue Scale (VAS) and Oxford Knee Score (OKS).The most common clinical characteristic in patients with MD-ACL was knee pain (18/18), and seconded by mobility limitation (38.9%, 7/18). All patients presented a typical celery stalk sign with increased signal and diffuse thickening volume in the ACL in MRI. Thirteen patients companied with meniscus tear (72.2%, 13/18), and nine complicated with cartilage injury (50.0%, 9/18). Sixteen patients who underwent conservative treatment were followed up for 21.8 months, and a positive clinical outcome was observed with VAS decreasing from 5.3 ± 2.3 to 1.5 ± 1.9 and OKS decreasing from 27.5 ± 12.7 to 17.9 ± 11.8 (p < 0.001). The post-OKS score was highly correlated with age, duration of disease, and meniscus tear (r = 0.844, 0.707, and 0.474, p < 0.05, respectively). And the post-VAS highly correlated with age (r = 0.693, p < 0.05). Two patients who underwent arthroscopic surgery were followed up for 24.5 months, and the pain and function of knee was improved.Knee pain and meniscus tear was the main characteristic of MD-ACL in clinical and radiographic exam. Conservative treatment could be an alternative management for treatment of MD-ACL with positive clinical outcome. Old age, long duration of disease and complications from meniscus tears were associated with inferior outcome of conservative treatment for MD-ACL.
Level of evidence IV.
National Inpatient Datasets May No Longer Be Appropriate for Overall Total Hip and Knee Arthroplasties Projections after Removal from Inpatient-Only Lists
Authors: Rullán Pedro J. , Emara Ahmed K. , Zhou Guangjin , Pasqualini Ignacio , Klika Alison K. , Koroukian Siran , Barsoum Wael K. , Piuzzi Nicolas S. 
Published: February 2023

AbstractIt is unknown if the National Inpatient Sample (NIS) remains suitable to conduct projections for total knee arthroplasty (TKA) and total hip arthroplasty (THA), after their removal from “inpatient-only lists” in 2018 and 2020, respectively. We aimed to: (1) quantify primary THA and TKA volume from 2008 to 2018; (2) project estimates of future volume of THA and TKA until 2050; and (3) compare projections based on NIS data from 2008 to 2018 and 2008 to 2017, respectively. We identified all primary THA and TKA performed from 2008 to 2018 from the NIS. The projected volumes of THA and TKA were modeled using negative binomial regression models while incorporating log-transformed population data from the Centers for Disease Control and Prevention. Annual volume increased by 26% for THA and 11% for TKA (2008/2018: THA: 360,891/465,559; TKA:592,352/657,294). Based on 2008 to 2018 data, THA volume is projected to grow 120%, to 1,119,942 THAs by 2050. While, based on 2008 to 2017 data, THA volume is projected to grow 136%, to 1,219,852 THAs by 2050. Based on 2008 to 2018 data, TKA volume is projected to grow 4%, to 794,852 TKAs by 2050. While, based on 2008 to 2017 data, TKA volume is projected to grow 28%, to 1,037,474 TKAs by 2050. Projections based on 2008 to 2017 data estimated up to 240,000 (23%) more annual TKAs by 2050, compared with projections based on 2008 to 2018 data. The largest discrepancy among THA projections was an 8.2% difference (99,000 THAs) for 2050. After 2018 for TKA, and potentially 2020 for THA, projections based on the NIS will have to be interpreted with caution and may only be appropriate to estimate future inpatient volume. Level of evidence is prognostic level II.
Association of Dietary Niacin Intake with Diabetes in Adults in the
United States
Authors: Liu Chan , Duan Wenjuan , Xu Wenming 
Published: February 2023

Abstract
Objective Previous studies have shown inconsistent associations between
niacin supplementation and diabetes, and little is known about the relationship
between dietary niacin intake and the risk of diabetes in the general
population. Our study aimed to explore the association between dietary niacin
intake and the risk of diabetes in the adult population in the United
States.
Methods Data from the 2005–2016 National Health and Nutrition
Examination Surveys were analyzed. Diabetes was diagnosed according to the
American Diabetes Association criteria. Multivariate logistic regression models
were used to estimate the association between dietary niacin intake and
diabetes. Covariates included age, sex, race, family income, educational level,
drinking status, smoking status, marital status, and physical activity.
Results This study included 24494 participants, of which 13.63%
had diabetes. In the fully adjusted model, a high niacin intake was
significantly associated with a reduced risk of diabetes in a dose-dependent
manner. When extreme quintiles of niacin intake were compared, the
multivariable-adjusted odds ratio was 0.66 (95% confidence interval:
0.49, 0.88) for diabetes, and per ten-unit increment in dietary niacin intake
was associated with a 14% lower risk of diabetes. When niacin intake was
less than 15.01 mg/d, a ten-unit increment in niacin intake was
associated with a 24% higher risk of diabetes. However, the effect was
not statistically significant.
Conclusions Our results suggest that the consumption of adequate amounts
of niacin can reduce the risk of diabetes. Furthermore, this protective effect
disappeared when the niacin intake was insufficient (less than
15.01 mg/d).
Placement of a Catheter into the Transverse Sinus in Monitoring Intracranial Lesions: A Technical Note
Authors: Dai Xingping , Chen Yanyi , Xia Mingyue , Yi Min , Xu Xia , Wang Dongsheng , Nemoto Edwin M. 
Published: February 2023

AbstractHigh intracranial pressure (ICP) can be induced by stroke, brain trauma, and brain tumor, and lead to cerebral injury. Monitoring the blood flow of a damaged brain is important for detecting intracranial lesions. Blood sampling is a better way to monitor changes in brain oxygen and blood flow than computed tomography perfusion and magnetic resonance imaging. This article describes how to take blood samples from the transverse sinus in a high ICP rat model. Also, it compares the blood samples from the transverse sinus and femoral artery/vein through blood gas analysis and neuronal cell staining. The findings may be of significance to the monitoring of the oxygen and blood flow of intracranial lesions.
Reactivation of Tuberculosis and COVID-19 in Pediatric Patients
Authors: Ünal Gökçen , Pekcan Sevgi , Metin Akcan Özge , Keleş Sevgi , Yılmaz Aslı İmran , Eldeniz Fadime Ceyda , Çağlar Hanife Tuğçe , Özdemir Mehmet , Poyraz Necdet , Kılınç Fahriye , Bulut Ayşe 
Published: February 2023

Abstract
Objective Mycobacterium tuberculosis is an immobile aerobic bacillus that causes tuberculosis (TB) disease. We aimed to evaluate the association between coronavirus disease 2019 (COVID-19), COVID-19-related drugs, TB reactivation, and TB incidence during the pandemic.
Methods Eight patients who were diagnosed as having TB in Meram Medical Faculty, Necmettin Erbakan University between March 1, 2020, and December 31, 2021, at the beginning of the pandemic, were enrolled in this study. The presence of COVID-19 infection was confirmed using COVID-19 antibody tests and the patients' COVID-19 history. We evaluated the demographic data, laboratory findings, imaging tests, and pathology results of all patients.
Results We checked all our patients with TB using COVID-19 antibodies (immunoglobulin [Ig]G + IgM) or polymerase chain reaction. Seven of the eight patients were female (87.5%). The median age was 16 years. Family screening of all patients was negative, and they had bacillus Calmette–Guérin vaccine scars. Two patients had chronic diseases. One was diagnosed as having primary ciliary dyskinesia in our department (patient no. 8) and the second was under follow-up by the rheumatology department with a diagnosis of juvenile idiopathic rheumatoid arthritis.
Conclusion There has been an increase in the incidence of TB in children, especially in adolescents, during the pandemic period. This may be due to the pathogenic structure of the COVID-19 virus with an unknown mechanism. In addition, lifestyle changes and changes in health care policies during the pandemic may have caused this. Further research should be performed on this topic.
Prevalence of Work-Related Musculoskeletal Symptoms in Veterinary Surgeons—A Cross-Sectional Survey
Authors: Kim Sun Young , Yu Denny , Simons Micha C. , Breur Gert J. 
Published: February 2023

Abstract
Objectives The aim of this study was to determine the prevalence of work-related musculoskeletal symptoms (MSS) in veterinary surgeons using an online survey.
Study Design An online survey was distributed to 1,031 diplomates of American College of Veterinary Surgeons. Responses were collected with data regarding surgical activities, experience with various types of MSS in 10 different body sites and attempts to reduce MSS.
Results Two hundred and twelve respondents (21% response rate) completed the distributed survey in 2021. Ninety-three per cent of respondents had experienced MSS associated with surgery in at least one body part, with the neck, lower back and upper back frequently affected. Musculoskeletal discomfort and pain worsened with prolonged surgical hours. Forty-two per cent of them suffered from chronic pain persisting longer than 24 hours after surgeries. Musculoskeletal discomfort was common regardless of practice emphasis and procedure types. Forty-nine per cent of respondents with musculoskeletal pain had taken medication, 34% sought physical therapy for MSS and 38% ignored the symptoms. Over 85% of respondents showed more than some concern regarding career longevity due to musculoskeletal pain.
Clinical Significance Work-related MSS are common in veterinary surgeons, and the results of this study warrant longitudinal clinical studies to determine risk factors and attention to workplace ergonomics in veterinary surgery.
Portal Vein Interventions for Portal Hypertension: Complications and Management
Authors: Novelli Paula M. , Polder Jason , Kaufman Claire , Orons Philip D. 
Published: February 2023

AbstractPercutaneous management of complications of portal hypertension entails reducing portal pressures, controlling varices, and redirecting collateral flow using embolization, obliterative, restorative, recanalization, and shunt creation techniques. Management is based on the clinical status and symptoms and the physiologic and anatomic abnormalities causing portal hypertension. This article briefly describes percutaneous management strategies, their results, and related iatrogenic and physiologic complications.
Outcomes of Elective Induction of Labor at 39 Weeks from a Statewide Collaborative Quality Initiative
Authors: Langen Elizabeth S. , Schiller Amy J. , Moore Kathryn , Jiang Charley , Bourdeau Althea , Morgan Daniel M. , Low Lisa Kane 
Published: February 2023

Objective This article evaluates the impact of adopting a practice of elective induction of labor (eIOL) at 39 weeks among nulliparous, term, singleton, vertex (NTSV) pregnancies in a statewide collaborative.
Study Design We used data from a statewide maternity hospital collaborative quality initiative to analyze pregnancies that reached 39 weeks without a medical indication for delivery. We compared patients who underwent an eIOL versus those who experienced expectant management. The eIOL cohort was subsequently compared with a propensity score-matched cohort who were expectantly managed. The primary outcome was cesarean birth rate. Secondary outcomes included time to delivery and maternal and neonatal morbidities. Chi-square test, t-test, logistic regression, and propensity score matching methods were used for analysis.
Results In 2020, 27,313 NTSV pregnancies were entered into the collaborative's data registry. A total of 1,558 women underwent eIOL and 12,577 were expectantly managed. Women in the eIOL cohort were more likely to be ≥35 years old (12.1 vs. 5.3%, p < 0.001), identify as white non-Hispanic (73.9 vs. 66.8%, p < 0.001), and be privately insured (63.0 vs. 61.3%, p = 0.04). When compared with all expectantly managed women, eIOL was associated with a higher cesarean birth rate (30.1 vs. 23.6%, p < 0.001). When compared with a propensity score-matched cohort, eIOL was not associated with a difference in cesarean birth rate (30.1 vs. 30.7%, p = 0.697). Time from admission to delivery was longer for the eIOL cohort compared with the unmatched (24.7 ± 12.3 vs. 16.3 ± 11.3 hours, p < 0.001) and matched (24.7 ± 12.3 vs. 20.1 ± 12.0 hours, p < 0.001) cohorts. Expectantly managed women were less likely to have a postpartum hemorrhage (8.3 vs. 10.1%, p = 0.02) or operative delivery (9.3 vs. 11.4%, p = 0.029), whereas women who underwent an eIOL were less likely to have a hypertensive disorder of pregnancy (5.5 vs. 9.2%, p < 0.001).
Conclusion eIOL at 39 weeks may not be associated with a reduced NTSV cesarean delivery rate.
Key Points
Assessment of Hemostatic Profile in Neonates with Intrauterine Growth Restriction: A Systematic Review of Literature
Authors: Karapati Eleni , Sokou Rozeta , Iliodromiti Zoi , Tsaousi Marina , Sulaj Alma , Tsantes Andreas G. , Petropoulou Chrysa , Pouliakis Abraham , Tsantes Argirios E. , Boutsikou Theodora , Iacovidou Nicoletta 
Published: February 2023

AbstractIntrauterine growth restriction (IUGR) affects nearly 10 to 15% of pregnancies and is responsible for many short- and long-term adverse consequences, including hemostatic derangement. Both thrombotic and hemorrhagic events are described in the perinatal period in these neonates. The aim of this study was to systematically review the literature on the laboratory studies used to evaluate the hemostatic system of the IUGR small for gestational age neonate. We reviewed the current literature via PubMed and Scopus until September 2022. Following our inclusion/exclusion criteria, we finally included 60 studies in our review. Thrombocytopenia, characterized as hyporegenerative and a kinetic upshot of reduced platelet production due to in utero chronic hypoxia, was the main finding of most studies focusing on growth-restricted neonates, in most cases is mild and usually resolves spontaneously with the first 2 weeks of life. In regard to coagulation, growth-restricted newborns present with prolonged standard coagulation tests. Data regarding coagulation factors, fibrinolytic system, and anticoagulant proteins are scarce and conflicting, mainly due to confounding factors. As thromboelastography/rotational thromboelastometry (TEG/ROTEM) provides a more precise evaluation of the in vivo coagulation process compared with standard coagulation tests, its use in transfusion guidance is fundamental. Only one study regarding TEG/ROTEM was retrieved from this population, where no difference in ROTEM parameters compared with appropriate for gestational age neonates was found. Despite the laboratory aberrations, no correlation could be achieved with clinical manifestations of bleeding or thrombosis in the studies included. More studies are needed to assess hemostasis in IUGR neonates and guide targeted therapeutic interventions.
Clinical Outcomes of Arthroscopic-Assisted Volar Scapholunate Capsulodesis: A Case Series
Authors: Kakar Sanjeev , Lui Hayman 
Published: February 2023

Abstract
Purpose We have previously described arthroscopic-assisted volar scapholunate (SL) capsulodesis as an alternative technique for addressing volar SL interosseous ligament (SLIL) injuries. In this article, we report the outcomes of this procedure in a cohort of patients.
Methods Postoperative outcomes including range of motion, grip strength, visual analog scale (VAS) pain score, Quick Disabilities of the Arm, Shoulder and Hand (QuickDASH), and Mayo Wrist Score were assessed through a prospective review of six patients in a single center who underwent this procedure.
Results Six patients (four male and two female) with a mean age of 43 ± 14 years were evaluated in the study. The mean duration of follow-up was 41 ± 17 weeks. Postoperative outcomes noted a reduction in VAS pain score from 8 before surgery to 0.7 postoperatively (p = 0.00004) and improvement in Mayo Wrist Score (42 preoperatively to 80 postoperatively; p = 0.001), grip strength (86% of contralateral side; p = 0.20), and flexion arc (81% of contralateral side; p = 0.08). QuickDASH was 20 ± 8 and Patient-Rated Wrist Evaluation score was 13 ± 2 at the last clinical follow-up. There was an improvement in SL gap (p = 0.03), SL angle (p = 0.11), and radiolunate angle (p = 0.15) measurements postoperatively.
Conclusions The described arthroscopic-assisted volar SL capsulodesis in this study presents an alternative method to address volar SLIL pathology with positive short-term clinical outcomes.
Clinical Relevance Arthroscopic-assisted volar SL capsulodesis may be considered in the treatment algorithm for volar SLIL injuries.
Best Practices for Writing Letters of Recommendation for Maternal-Fetal Medicine Fellowship: An Empty Scoping Review
Authors: Dotters-Katz Sarah K. , Kirsch Elayna , Cantrell Sarah , Shanks Anthony , Temming Lorene , Gray Beverly 
Published: February 2023

Objectives Though letters of recommendation (LOR) for Maternal-Fetal Medicine (MFM) fellowship are a critical part of application process, little is known regarding best practices for writing them. This scoping review sought to identify published data outlining best practices in writing MFM fellowship LOR.
Study Design Scoping review conducted using Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) and JBI guidelines. MEDLINE, Embase, Web of Science, and ERIC were searched, by professional medical librarian using database-specific controlled vocabulary and keywords representing MFM, fellowship, as well as personnel selection, academic performance, examinations, or clinical competence in 4/22. Prior to execution, the search was peer reviewed by another professional medical librarian using the Peer Review Electronic Search Strategies (PRESS) checklist. Citations imported to Covidence, dual screened by authors with disagreements resolved by discussion, and extraction performed by one author and checked by the second.
Results A total of 1,154 studies were identified, with 162 removed as duplicates. Of the 992 screened, 10 imported for full-text review. None of these met inclusion criteria; four were not about fellows and six did not report on best practices for writing LOR for MFM.
Conclusion No articles were identified that outlined best practices for writing LOR for MFM fellowship. The lack of guidance and published data guiding those writing LOR for MFM fellowship applicants is concerning given the importance of these as a tool used by fellowship directors in selecting applicants for interviews and ranking.
Key Points
Bottom-up building of two-dimensional magnetic materials with self-assembly of superatom TM@Sn12 (TM = Sc, Ti, V, Cr, Mn, Fe) clusters
Authors: Chen Lixuan , Guo Ping , Zheng Jiming , Zhao Puju , Jiang Zhenyi , Shen Lei 
Published: February 2023

Abstract
The miniaturization of electronic devices is increasingly requiring some low-dimensional magnetic materials with excellent properties, so ultra-thin two-dimensional magnetic materials have attracted extensive attention. However, most two-dimensional materials exfoliated from bulk either lack intrinsic magnetism or have low magnetic transition temperatures, which greatly limits their practical applications. Here, using magnetic superatom TM@Sn12 (TM = Sc, Ti, V, Cr, Mn, Fe) clusters as building blocks, a series of two-dimensional materials are designed and the underlying mechanism for magnetic order and stability are explained by direct exchange of outer superatom orbitals (1G, 2P and 2D). The honeycomb lattice of TM@Sn12 (TM = V, Cr, Fe) and the square lattice of Ti@Sn12 are ferromagnetic. The Cr@Sn12 honeycomb lattice has a large out-of-plane magnetic anisotropic energy of 2.21 meV and its Curie temperature reaches 162 K, while the Fe@Sn12 honeycomb lattice has a large in-plane magnetic anisotropic energy of 3.58 meV. This research provides a new avenue for developing novel magnetic materials with excellent properties.
Ionization wave propagation of a surface dielectric barrier discharge with a flexible-structure plasma sheet
Authors: Sun Yuhao , Zhang Bo , Zhao Hang , Han Wenhu , Li Wendong , Zhang Guanjun 
Published: February 2023

Abstract
Plasma sources based on flexible substrates are receiving attention due to their unique adaptability to irregular surfaces and large range of plasma coverage, which endows them with irreplaceable advantages in the fields of material processing and biomedical treatment. Numerous studies have been carried out focusing on the application effects of these flexible plasma sources, while their surface discharge characteristics and mechanisms still lack revelation. In this work, a flexible plasma sheet with a surface dielectric barrier discharge structure is realized via a printed circuit board, and its multiple surface ionization wave (SIW) propagation on curved gas–solid interfaces is studied via experiments and 2D fluid simulation models. Qualitative agreement is achieved between the experiments and simulations. It is found that a positive and a negative discharge are generated at the rising and falling edges of the excitation pulse, respectively. In the positive discharge, SIWs originate at the grounded mesh edge and then propagate to the center in a petal-like pattern, which is shaped by the space electric field. Controlled by electron collision reactions, the development of the excited states of N2 and O2 molecules is similar to that of electrons. In the negative discharge, electrons dissipate and no SIW is generated. The evolution of heavy particles shows differences in this period, which is attributed to the disparate rate coefficients of their consumption reactions. Further study shows that when the plasma sheet changes from convex to concave, the electron density and electron temperature above its surface increase, but the petal patterns of the SIW propagation have no variation. The electron density, electron temperature, and electron impact ionization source will rise as a result of the increasing pulse amplitude or the decreasing duration of the pulse rising edge.