bluuebunny/crossref_metadata_2025_split huggingface dataset:
Middle ear adenoma: Cytohistologic features and differential diagnosis
Authors: Almajnooni Abdullah , Vega Matthew , Cheng Lin , Gattuso Paolo , Allen‐Proctor Mary K. 
Published: January 2023

AbstractMiddle ear adenomas are rare, low grade glandular neoplasms with epithelial and neuroendocrine components and with varying patterns of differentiation. Due to the rarity of this tumor, there is a dearth of publications detailing the cytological features. We herein review our institution's pathological database for cytological material between 1992 and 2022 for MEA specimens and discuss possible differential diagnoses based on clinical, pathological, and cytologic data and material.
Distinguishing apathy from depression: A review differentiating the behavioral, neuroanatomic, and treatment‐related aspects of apathy from depression in neurocognitive disorders
Authors: Lanctôt Krista L. , Ismail Zahinoor , Bawa Kritleen K. , Cummings Jeffrey L. , Husain Masud , Mortby Moyra E. , Robert Philippe 
Published: January 2023

AbstractObjectivesThis narrative review describes the clinical features of apathy and depression in individuals with neurocognitive disorders (NCDs), with the goal of differentiating the two syndromes on the basis of clinical presentation, diagnostic criteria, neuropathological features, and contrasting responses to treatments.MethodsLiterature was identified using PubMed, with search terms to capture medical conditions of interest; additional references were also included based on our collective experience and knowledge of the literature.ResultsEvidence from current literature supports the distinction between the two disorders; apathy and depression occur with varying prevalence in individuals with NCDs, pose different risks of progression to dementia, and have distinct, if overlapping, neurobiological underpinnings. Although apathy is a distinct neuropsychiatric syndrome, distinguishing apathy from depression can be challenging, as both conditions may occur concurrently and share several overlapping features. Apathy is associated with unfavorable outcomes, especially those with neurodegenerative etiologies (e.g., Alzheimer's disease) and is associated with an increased burden for both patients and caregivers. Diagnosing apathy is important not only to serve as the basis for appropriate treatment, but also for the development of novel targeted interventions for this condition. Although there are currently no approved pharmacologic treatments for apathy, the research described in this review supports apathy as a distinct neuropsychiatric condition that warrants specific treatments aimed at alleviating patient disability.ConclusionsDespite differences between these disorders, both apathy and depression pose significant challenges to patients, their families, and caregivers; better diagnostics are needed to develop more tailored treatment and support.
Qualitative analysis of the most locally relevant runoff and erosion parameters for constructing Brazilian scenarios
Authors: Casallanovo Fábio , Santos Gustavo S. , Cione Ana P. , Simone Daniela M. , de Oliveira Kaminski Thamires S. , Chen Wenlin 
Published: January 2023

Abstract
Estimating exposure is one of the most important steps in an environmental risk analysis of crop-protection products to nontarget organisms. Regulatory agencies such as the US Environmental Protection Agency (USEPA), Pest Management Regulatory Agency (PMRA), and European Food Safety Authority (EFSA) all use mathematical exposure models in their regulatory assessment process. Brazil has been discussing the adoption of the Pesticide in Water Calculator (PWC) to be applied in aquatic pesticide risk assessment. Therefore, a qualitative sensitivity analysis (Morris OAT method) was performed to understand which are the most important local parameters in the PWC to estimate environmental concentrations in surface water (EECSW). In addition, an exercise made up of two corn scenarios in two Brazilian regions was developed (Uberlândia [UDI] and Arapoti [ARA]). Two herbicides with different soil-binding properties and modes of action were selected to estimate the EECSW. The results demonstrated that the parameters of importance were different for each site, probably the result of different soil characteristics and meteorological patterns. This outcome suggests that regulatory agencies should consider developing more than one scenario to account for different agricultural regions. For Herbicide 1, the EECSW for UDI were similar to US scenarios, whereas for ARA they were lower. For Herbicide 2, the EECSW for the UDI site was higher than most of the US scenarios, whereas at the ARA site, EECs were similar to four US scenarios and lower than the other six. Local data were used as a refinement, resulting in the decrease in the EECSW for both herbicides in the UDI site. For the ARA site, Herbicide 1 displayed a similar EECSW value, whereas for Herbicide 2, it was lower after the refinement. Overall, these results demonstrated the importance of developing local scenarios to provide more realism to estimate pesticide exposure from its agricultural use and may help regulators to determine and recommend mitigations regarding the use of crop-protection products. Integr Environ Assess Manag 2023;19:1374–1384. © 2023 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals LLC on behalf of Society of Environmental Toxicology & Chemistry (SETAC).
Impact of appendectomy of a grossly normal appendix on the survival outcomes of mucinous ovarian carcinomas in a tertiary hospital
Authors: Peeyananjarassri Krantarat , Nanthamongkolkul Kulisara , Jiamset Ingporn , Chusook Wuttipong , Boonyapipat Sathana , Buhachat Rakchai 
Published: January 2023

AbstractObjectiveTo evaluate the survival outcomes of appendectomy for a grossly normal appendix in patients with mucinous ovarian carcinomas.MethodsRetrospective cohort study. Patients with mucinous ovarian carcinomas with grossly normal appendices who underwent primary surgery between 2002 and 2022 were enrolled. The overall survival (OS) and progression‐free survival (PFS) of appendectomy and non‐appendectomy groups were analyzed using the Kaplan–Meier method and compared using the log‐rank test. Univariate and multivariate Cox regression analyses were used to determine the independent factors associated with OS and PFS.ResultsOf 192 patients, appendectomy was performed in 138 (71.9%). Three (1.6%) patients had primary appendiceal tumors and two (1.0%) had appendiceal metastases of ovarian origin. The median follow‐up time was 68.8 months. The OS and PFS were better in patients in the appendectomy group than in those in the non‐appendectomy group (5‐year OS: 80.72% vs. 65.05%, P = 0.012; 5‐year PFS: 76.32% vs. 58.60%, P = 0.020). Independent factors associated with poor OS and PFS were no omentectomy, peritoneal seeding, and advanced International Federation of Gynecology and Obstetrics (FIGO) stage.ConclusionAppendectomy of a grossly normal appendix was not an independent prognostic factor for OS and PFS in patients with mucinous ovarian carcinomas.
Beef price spread relationship with processing capacity utilization
Authors: Martinez Charles , Li Pengzhen , Boyer Christopher N. , Yu T. Edward , Maples Joshua G. 
Published: January 2023

AbstractWe investigate the relationships of the often‐publicized live cattle to box beef price spread and weekly and Saturday slaughter capacity utilization (CU). We find that an increase in the price spread in the previous period does positively impact national Saturday slaughter CU under a low price spread regime, but not in the identified middle and high regimes. Also, changes in weekly or Saturday slaughter CU does not impact the price spread except for the high regime. Our results do not support the notion that weekly, or Saturday slaughter CU is used by the beef packers to control the price spread.
Global financial uncertainty
Authors: Caggiano Giovanni , Castelnuovo Efrem 
Published: January 2023

SummaryWe estimate a novel measure of global financial uncertainty (GFU) with a dynamic factor framework that jointly models global, regional, and country‐specific factors. We quantify the impact of GFU shocks on global output with a VAR analysis that achieves set identification via a combination of narrative, sign, ratio, and correlation restrictions. We find that the contraction in world output during the Great Recession would have been 13% milder in absence of GFU shocks. We also find support for a global finance uncertainty multiplier: the more global financial conditions deteriorate after a GFU shock, the larger the world output contraction is.
Chemical industry wastewater treatment by coagulation combined with Fenton and photo‐Fenton processes
Authors: Metin Seda , Çifçi Deniz İzlen 
Published: January 2023

AbstractBACKGROUNDChemical industry wastewater is challenging to treat because of the various chemicals they contain. In this study, the treatment of chemical industry wastewater, which produces a wide variety of chemical aids, such as foam control agents, and silicones used in the textile, food and cosmetics industries, by coagulation combined with Fenton or photo‐Fenton oxidation processes was investigated. In coagulation studies, optimum pH and coagulant dose were determined with polyaluminum chloride (PAC), polyaluminum chloride hydroxide sulfate (PACS) and FeCl3 coagulants, while Fe2+, H2O2, pH and oxidation time were optimized in Fenton studies.RESULTSIn the coagulation, higher wastewater treatment was achieved with PAC compared to PACS and FeCl3 coagulants, and 62.6% chemical oxygen demand (COD) and 44.3% total organic carbon (TOC) removal were obtained at 500 mg L−1 PAC and pH 8. In the coagulation and Fenton oxidation, 92.4% COD, 79.7% TOC, 99.8% turbidity, and 96.7% total soluble solids (TSS) were achieved. The application of photo‐Fenton oxidation instead of Fenton oxidation did not cause a significant change in chemical industry wastewater. The cost of chemical industry wastewater treatment by coagulation and Fenton oxidation was calculated as $19.16 m−3, and the cost per kilogram of CODremoved was determined as $2.89 kg−1.CONCLUSIONIn chemical industry wastewater treatment, high TSS and turbidity removal can be achieved by coagulation with PAC, and the wastewater load subjected to Fenton oxidation can be reduced. Efficient wastewater treatment was provided by Fenton oxidation after coagulation. The application of the photo‐Fenton oxidation process instead of Fenton oxidation did not show the expected effect. However, toxicity studies should be performed in treated wastewater using coagulation–Fenton oxidation processes in future studies. © 2023 The Authors. Journal of Chemical Technology and Biotechnology published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry (SCI).
Enhancing butanol production by Clostridium beijerinckii through cathodic electrofermentation approach
Authors: Molognoni Daniele , Vega Maria , de Vrije Truus , Contreras Ana Lopez , Bosch Montse , Bosch‐Jimenez Pau , Borràs Eduard 
Published: January 2023

AbstractBACKGROUNDBiobutanol, produced by solventogenic bacteria like Clostridium beijerinckii through acetone, butanol, and ethanol (ABE) fermentation, is a promising green alternative to fossil fuels. However, this ABE fermentation suffers drawbacks, such as a relatively low productivity that limits its industrial deployment. Electro‐fermentation (EF) can modify the intracellular ratio of oxidized nicotinamide adenine dinucleotide to reduced nicotinamide (NAD+/NADH), a critical factor for butanol synthesis by C. beijerinckii, thus allowing higher product titers (or productivity) to be reached.RESULTSThe present study focuses on glucose‐based ABE‐EF at laboratory‐scale. Three replicate EF reactors (300 mL) were constructed and used to grow C. beijerinckii. Different cathode materials were electrochemically characterized and tested. The effect of voltage application on process productivity was assessed by performing chronoamperometry tests at constant cathode potential (Ecat), ranging from −0,7 to −1,0 V vs Ag/AgCl. These trials were compared with a benchmark ABE fermentation that was performed without voltage application. Poising Ecat at −0,8 V vs Ag/AgCl resulted in the optimal EF scenario. In these conditions, the specific growth rate of bacteria was 73% higher than the benchmark ABE fermentation, with a productivity of 125,6 mg‐butanol/L/h, a process yield of 0,15 g‐butanol/g‐glucose, and a selectivity for butanol of 87% (34%, 25%, and 11% higher than the benchmark fermentation, respectively). The addition of 0,5 mM neutral red as redox mediator in the broth led to a further improvement of butanol productivity (152,9 mg L h−1), requiring a very low energy consumption of 0,02 kWh/kg‐butanol to run the EF process.CONCLUSIONApplying EF enhances the ABE fermentation in terms of butanol production, selectivity, and energy consumption. © 2023 Society of Chemical Industry (SCI).
Low prevalence of influenza viruses and predominance of A(H3N2) virus with respect to SARS‐CoV‐2 during the 2021–2022 season in Bulgaria
Authors: Korsun Neli , Trifonova Ivelina , Dobrinov Veselin , Madzharova Iveta , Grigorova Iliyana , Christova Iva 
Published: January 2023

AbstractSocial distancing, mask‐wearing, and travel restrictions during the COVID‐19 pandemic have significantly impacted the spread of influenza viruses. The objectives of this study were to analyze the pattern of influenza virus circulation with respect to that of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) in Bulgaria during the 2021–2022 season and to perform a phylogenetic/molecular analysis of the hemagglutinin (HA) and neuraminidase (NA) sequences of representative influenza strains. Influenza infection was confirmed using real‐time reverse transcription polymerase chain reaction in 93 (4.2%) of the 2193 patients with acute respiratory illness tested wherein all detected viruses were subtyped as A(H3N2). SARS‐CoV‐2 was identified in 377 (24.3%) of the 1552 patients tested. Significant differences in the incidence of influenza viruses and SARS‐CoV‐2 were found between individual age groups, outpatients/inpatients, and in the seasonal distribution of cases. Two cases of coinfections were identified. In hospitalized patients, the Ct values of influenza viruses at admission were lower in adults aged ≥65 years (indicating higher viral load) than in children aged 0–14 years (p < 0.05). In SARS‐CoV‐2‐positive inpatients, this association was not statistically significant. HA genes of all A(H3N2) viruses analyzed belonged to subclade 3C.2a1b.2a. The sequenced viruses carried 11 substitutions in HA and 5 in NA, in comparison to the vaccine virus A/Cambodia/e0826360/2020, including several substitutions in the HA antigenic sites B and C. This study revealed extensive changes in the typical epidemiology of influenza infection, including a dramatic reduction in the number of cases, diminished genetic diversity of circulating viruses, changes in age, and seasonal distribution of cases.
Person‐organization fit and turnover intention: The mediating role of need‐supply fit and demand‐ability fit
Authors: kakar Abdul Samad , Rauza Dr , Raziq Abdul , Akhtar Tahir , Mohammad Nida 
Published: January 2023

AbstractThe Great Resignation indicates that many organizations are grappling with the human resource challenge of staff retention and turnover, in which fit plays a prominent role. Extrapolating the role of fit, this study investigates the effects of person‐organization fit, need‐supply fit, and demand‐ability fit on turnover intention. The study also investigates whether need‐supply fit and demand‐ability fit mediates the effect of person‐organization fit on turnover intention. The data gathered from 250 full‐time faculty members was analyzed using partial least squares structural equation modeling (PLS‐SEM) through SmartPLS. The results showed that (i) need‐supply fit and person‐organization fit had a negative and direct impact on turnover intentions, (ii) the impact of demand‐ability fit on turnover intention was insignificant, and (iii) the association between person‐organization fit and turnover intention is mediated by need‐supply fit. These findings are useful for management and practitioners in designing strategies that enhance employees’ compatibility with their workplace and help in reducing employees’ turnover intention. Noteworthily, this is one of the first research to look at the direct and indirect effects of person‐organization fit on turnover intention through need‐supply fit and demand‐ability fit.
Digital business model innovation among small and medium‐sized enterprises (SMEs)
Authors: Teoh Ming Fang , Ahmad Noor Hazlina , Abdul‐Halim Hasliza , Kan Wen Huey 
Published: January 2023

AbstractDigital business model innovation (DBMI) has been acknowledged as a new business norm which allows for increased competitiveness. By adopting the dynamic capabilities theory, this research aims to investigate the adoption of DBMI among small and medium‐sized enterprises (SMEs) in a developing country. The qualitative data were collected using semi‐structured virtual interviews with SMEs. The findings revealed that the SMEs have redesigned their DBMI through value creation innovation, which refers to the use of new digital technology, new capability, and strong collaboration with new partners to streamline the business processes. SMEs innovate their value proposition by focusing on new product and service offerings and creating profitable customer relationships. Interestingly, SMEs also implement value delivery innovation, utilizing new delivery channels to target new market segments. In terms of value capture innovation, SMEs are concerned with obtaining new sources of revenues at a lower cost structure. Research studies on DBMI in Malaysia are scarce. The originality of this research lies in the exploration of DBMI in the real‐life business context, and the insights it will provide to SMEs and practitioners in the midst of adopting DBMI. The findings offer valuable insights for SMEs, practitioners, and policymakers in emerging economies.
Prospective evaluation of multidimensional health‐related quality of life after endoscopic endonasal surgery for pituitary adenomas using the endoscopic endonasal sinus and skull base surgery questionnaire
Authors: Joustra Gonneke E. , ten Dam Ellen , Vermeulen Karin M. , Korsten‐Meijer Astrid G. W. , Appelman Auke P. A. , Feijen Robert A. 
Published: January 2023

AbstractObjectiveSocial functioning is an important factor in the evaluation of postoperative health‐related quality of life (HRQoL) for pituitary adenoma patients. In a prospective cohort study multidimensional HRQoL of non‐functioning (NFA) and functioning (FA) pituitary adenoma patients were evaluated following endoscopic endonasal surgery using the endoscopic endonasal sinus and skull base surgery questionnaire (EES‐Q).MethodsProspectively, 101 patients were included. The EES‐Q was completed preoperatively and postoperatively (2 weeks, 3 months, 1 year). Sinonasal complaints were completed daily during the first week postoperatively. Preoperative and postoperative scores were compared. A generalized estimating equation (uni‐ and multivariate) analysis was performed to identify significant HRQoL changes related to selected covariates.ResultsTwo weeks postoperatively, physical (p < .05) and social (p < .05) HRQoL are worse and psychological (p < .05) HRQoL improved compared with preoperatively. Three months postoperatively, psychological HRQoL (p = .01) trended back to baseline and no differences in physical or social HRQoL were reported. One year postoperatively, psychological (p = .02) and social (p = .04) HRQoL improved while physical HRQoL remained stable. FA patients report a worse HRQoL preoperatively (social, p < .05) and 3 months postoperatively (social, p < .02 and psychological, p < .02). Sinonasal complaints peak in the first days postoperatively and gradually return to presurgical levels 3 months postoperatively.ConclusionsThe EES‐Q provides meaningful information on multidimensional HRQoL to improve patient‐centred health care. Social functioning remains the most difficult area in which to achieve improvements. Despite the relatively modest sample size, there is some indication that the FA group continues to show a downward trend (and thus improvement) even after 3 months, when most other parameters reach stability.Level of evidenceLevel II—B.
Monolithically Integrated Active Passive Waveguide Array Fabricated on Thin Film Lithium Niobate Using a Single Continuous Photolithography Process
Authors: Zhou Yuan , Zhu Yiran , Fang Zhiwei , Yu Shupeng , Huang Ting , Zhou Junxia , Wu Rongbo , Liu Jian , Ma Yu , Wang Zhe , Yu Jianping , Liu Zhaoxiang , Zhang Haisu , Wang Zhenhua , Wang Min , Cheng Ya 
Published: January 2023

AbstractThis work demonstrates a robust low‐loss optical interface by tiling passive (i.e., without doping of active ions) thin film lithium niobate (TFLN) and active (i.e., doped with rare earth ions) TFLN substrates for monolithic integration of passive/active lithium niobate photonics. The tiled substrates composed of both active and passive areas allow for patterning the mask of the integrated active passive photonic device at once using a single continuous photolithography process. The interface loss of tiled substrate is measured as low as 0.26 dB. Thanks to the stability provided by this approach, a four‐channel waveguide amplifier is realized in a straightforward manner, which shows a net gain of 5 dB at a 1550‐nm wavelength and 8 dB at a 1530‐nm wavelength for each channel. The robust low‐loss optical interface for passive/active photonic integration will facilitate large‐scale high performance photonic devices that require on‐chip light sources and amplifiers.
A Sub‐Picojoule per Bit Integrated Magneto‐Optic Modulator on Silicon: Modeling and Experimental Demonstration
Authors: Rombouts Marijn P. G. , Karinou Fotini , Pintus Paolo , Huang Duanni , Bowers John E. , Calabretta Nicola 
Published: January 2023

AbstractIntegrated magneto‐optic (MO) modulators are an attractive but not fully explored alternative to electro‐optic (EO) modulators. They are current driven, structurally simple, and could potentially achieve high efficiency in cryogenic and room temperature environments where fJ bit−1optical interfaces are needed. In this paper, the performance and energy efficiency of a novel MO modulator at room temperature are for the first time assessed. First, a model of the micro‐ring‐based modulator is implemented to investigate the design parameters and their influence on the performance. Then, a fabricated device is experimentally characterized to assess its performance in terms of bit rate and energy efficiency. The model shows efficient operation at 1.2 Gbps using a 16 mA drive current, consuming only 155 fJ bit−1. The experimental results show that the MO effect is suitable for modulation, achieving error‐free operation above 16 mA with a power consumption of 258 fJ bit−1at a transient limited data rate of 1.2 Gbps.