bluuebunny/crossref_metadata_2025_split huggingface dataset:
First Exploratory Multilateral Project in Colombia: Taking Exploration to the Limit, Reducing Environmental Impact
Authors: Jaramillo L. F. , Campos N. , Sanchez J. J. , Jimenez L. M. , Acevedo H. G. 
Published: June 2023

Abstract
The oil and gas industry needs continuously improving in the exploration and extraction methods with a special care and strong compromise to maintain the equilibrium with environment. Based on that mission, and in compliance with the Parex Resources Greenhouse Gases and Climate strategy, Parex Resources executed the first multilateral drilling project in Colombia. It was an ambitious and challenging exploration campaign. The goal was to improve the exploration area by drilling multiples branches through different geological units and total vertical depths (TVD) into an overpressured naturally fractured field. The field presented a complex geological and structural environment. Expectations were high for both drilling optimization and formation evaluation of a compartmentalized reservoir, looking to cover the highest extension while drilling fewer wells from the surface.
Considering the level of the challenge ahead, the solution was articulated in three critical fronts:Develop a vigorous planning with service company and operator engineering team for casing design, mud weight window and system, bottomhole assembly (BHA) design, and fit for purpose technology for directional drilling operations.Include a full set of logging data with reliable logging-while-drilling (LWD) tools and advanced mud logging services to fulfill geology requirements, as no wireline logging was planned due to constrains in a horizontal borehole.Implement well placement services with the most experienced team to geo-steer based on real-time data completely integrated for precise interpretation.
The operational efficiency achieved was beyond expectations in all areas of well construction, not to mention the project cost reduction through the multilateral approach, preventing to drill three wells from surface. In this case, three different geological compartments were explored from one surface location. This innovative exploration approach also brought important gains on the environmental impact as surface operations were dramatically minimized compared to conventional exploration. This strategy helped the operator and service company to reduce the carbon footprint, simply by reducing the number of wells and operational days needed to explore new fields.
Development and Application of Water and Polymer Injection Control Valves Including Memory Recording of Flow and Pressure to Improve Secondary Recovery Surface and Downhole for Completion Using Side Pocket Mandrels: Case Histories
Authors: Torne Juan Pablo , Prada Alvaro , Parra Marly Fabiola , Munoz Lina Raquel , Acosta Tito Jose , Berdugo Carlos Fernando , Gonzalez John Edison , Penuela Gabriela , Perez Gerson Saul , Hernandez Nini Joana , Gomez Ivan Camilo , Diaz Fabian Andrey 
Published: June 2023

Abstract
The control of water and polymer injection in secondary recovery processes in multilayer reservoirs is important to optimize and control the process to maintain reservoir pressure, displacement of residual oil and sustaining production from oil fields. Injection control and monitoring technology for surface and downhole has been developed focused on procedures to maintain efficiency and cost control which is critical for mature fields.
Water and polymer Injection control special valves and different control modules including multiple stages of reducers and expansion chambers and barriers or panels to reduce flow speed have been designed, model, manufactured and used after being patented together with Ecopetrol. They also include flow and pressure parameters recording for better control of the process. The use of polymers for injection processes has proven to be effective in improving recovery, however, it is necessary to guarantee the integrity of the polymer reducing viscosity degradation by controlling the mechanical design to reduce friction and control pressure drop and injection flow.
In general, the system has proven to be highly reliable, nearly 1,000 water modules have been installed, they operate within the requirements and flow design required according to reservoir conditions and known differential pressures optimizing cost and sweep efficiency. The extension of polymer injection project also include the use of these valves predicting damage for better design and optimization. On average, the regulators have a duration of 1-4 years, which is very positive for additional installation and removal services and spare parts cost optimization. In general, the system has fulfilled the objective of improving the injection of water and polymer efficiency at a lower price of the equipment without counting the extension of the life time of each national manufacturing module, this fact combined with improvements in the efficiency of the entire process is reflected in greater profitability. The addition of a memory recording module for pressure and injection rate is important for surveillance and follow up maintaining and optimizing injection and production.
This paper shows the added value of using water or polymer injection selective valves for multilayer and heavy oil reservoirs to improve and stabilize production and injection rates, having also the option to monitor and record the dynamic/static pressure and injection rate. This is novel a tool for reservoir and production/injection engineers to optimize enhanced oil recovery in heavy oil and mature fields.
Innovative Design and Numerical Simulation Research of Downhole Electrical Heaters for In-Situ Oil Shale Exploitation
Authors: Sun Tengfei , Liu Hao , Yan Tingjun , Zhang Yang , Wu Baokang , Liu Ziyang , Wang Zhilei , Fan Yacong , Li Yongan , Han Yongliang 
Published: June 2023

Summary
To improve the overall performance of continuous spiral baffle heating systems, we propose in this paper two different structural models of electric heaters for in-situ shale oil wells. The models are simulated using Fluent software to investigate the flow and heat-transfer characteristics under different mass flow rates. The variation in heat-transfer coefficient, pressure drop, and overall performance of the heating plate under different gas mass flow rates and heights of heating and shielding plates are analyzed. The performance of the two different heater structures is compared with Wang’s laboratory experiment. The results show that Model I of the heating system has the best overall performance when the gas mass flow rate is between 9.74×10−3 kg/s and 1.624×10−2 kg/s, and the height of the heating and shielding plates is 35 mm at a mass flow rate of 9.74×10–3 kg/s. Wang’s pressure drop (ΔP) is more than 2.48 times higher than that of Model I and more than 6.49 times higher than that of Model II, while the heat-transfer coefficient (h) of both Model I and Model II is increased by more than 15% compared to Wang’s experiment. The overall performance (g) of Model II is increased by more than 5.7 times compared to Wang’s experiment, and the overall performance (g) of Model II is increased by more than 1.68 times compared to Model I. These results provide a theoretical basis for optimizing the design of continuous spiral baffle heating systems.
Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH, reveals the unique mode of mycobacterial ribosome hibernation
Authors: Kaushal Prem , Kumar Niraj , Sharma Shivani 
Published: June 2023

Abstract
Ribosome hibernation is a key survival strategy bacteria adopt under environmental stress, where a protein, hibernation promotion factor (HPF), transitorily inactivates the ribosome and slows down its overall protein synthesis. The mechanism is well studied in enteric bacteria, which mainly hibernate its ribosome in 100S disome form through a dual domain, long HPF (HPFlong) or a single domain, short HPF (HPFshort) in concert with another ribosome modulation factor. Mycobacterium tuberculosis encounters hypoxia (low oxygen) as a major stress in the host macrophages, and it overexpresses RafH protein, which is critical for its survival. The RafH, a dual domain HPF, an orthologue of bacterial HPFlong, hibernates ribosome in 70S monosome form only. Here we report the cryo- EM structure of Mycobacterium smegmatis, a close homologue of M. tuberculosis, 70S ribosome in complex with the RafH factor at an overall 2.8 Å resolution. The RafH N- terminus domain (NTD) is conserved and binds to the decoding center of the ribosomal small subunit, a similar binding for HPFlong NTD, but additionally it also interacts with the inter subunit bridge, B2a. Contrary to the HPFlong C- terminus domain (CTD), the RafH CTD, which is larger, binds to a unique site at the platform binding center of the ribosomal small subunit and sandwiches between bS1 and uS11 ribosomal proteins. The two domain connecting linker regions, which remain mostly disordered in earlier reported HPFlong structures, interacts mainly with the anti-Shine Dalgarno sequence of the 16S rRNA. The helix H54a of 23S rRNA, unique to the mycobacterial ribosome, adopts a different conformation and come close to RafH CTD, suggesting its role in ribosome hibernation. RafH inhibits in-vitro protein synthesis in a concentration dependent manner. Further, the modeling studies provided the structural basis for the incompatibility of mycobacterial ribosomes to form 100S like disome architecture.
A comparative study between backpropagation and general regression neural networks to predict tensile properties of fused filament fabricated parts
Authors: Cerda-Avila Steffany N. , Medellin-Castillo Hugo I , Cuevas-Tello Juan C. 
Published: June 2023

Abstract
The Fused Filament Fabrication (FFF) process comprises a large number of process parameters that affect the resultant mechanical properties of the parts, and that generates uncertainties in the design for Additive Manufacturing process. The use of Artificial Neural Networks (ANN) based on classification machine learning techniques such as Backpropagation Neural Networks (BPNN) have been proposed in the literature to evaluate the dimensional accuracy, surface roughness, compressive, flexural and tensile strength of FFF parts. As an alternative, in this paper a new General Regression Neural Networks (GRNN) approach, based on a regression machine learning technique, is proposed and compared with the performance of a BPNN to estimate the tensile structural properties of PLA-FFF parts using variable process parameters. The comparison and evaluation are based on their capability to accurately predict the experimental Ultimate Tensile Stress (UTS) and the Elastic Modulus (E). The results have shown that although the BPNN and the GRNN are able to estimate with high accuracy the structural behaviour of FFF parts, the new proposed GRNN better fits the experimental results and the current needs of Design for Additive Manufacturing (DfAM).
Differences in delivery hospitalization experiences during the COVID-19 pandemic by maternal race and ethnicity, Pregnancy Risk Assessment Monitoring System, 2020
Authors: Meghani Mehreen , Meeker Jessica , Zapata Lauren , Galang Romeo , von Essen Beatriz Salveson , Dieke Ada , Ellington Sascha , Simeone Regina 
Published: June 2023

Abstract

ObjectiveWe investigated maternal COVID-19 related experiences during delivery hospitalizations, and whether experiences differed by maternal race and ethnicity.StudydesignData from the Pregnancy Risk Assessment Monitoring System among women with live births between April–December 2020 were used. Adjusted prevalence ratios (aPR) and 95% confidence intervals (CI) estimated associations between maternal race and ethnicity and COVID-19 related delivery experiences.ResultsAmong 12 879 women, 3.6% reported infant separation and 1.8% reported not being allowed support persons. Compared with non-Hispanic White women, American Indian/Alaska Native (AI/AN) (aPR=2.7; CI: 1.2-6.3), Hispanic (aPR=2.2; CI: 1.5-3.1), non-Hispanic Black (aPR= 2.4; CI: 1.7-3.5), and non-Hispanic Asian (aPR= 2.9; CI: 1.7-4.9) women reported more infant separation due to COVID-19. Not being allowed support persons was more common among AI/AN (aPR=5.3; CI: 1.8-15.4) and non-Hispanic Black (aPR=2.3; CI: 1.3-4.1) women.ConclusionsCOVID-19 related delivery hospitalization experiences were unequally distributed among racial and ethnic minorities.
Bilateral Nephromegaly and Spontaneous Tumor Lysis Syndrome as an Initial Manifestation of Pre-T Acute Lymphoblastic Leukemia: Case Report and Review of the Literature.
Authors: Ivan Zepeda-Quiroz , Fernanda Coss-Rovirosa , Sebastian Toledo-Ramirez , Victor Gomez-Johnson , Daniel Juarez-Villa , Brian Garibay-Vega , Salvador Lopez-Gil 
Published: June 2023

Abstract

Background
Acute lymphoblastic leukemia is relatively rare in adults and kidney manifestations are extremely infrequent. Acquired bilateral nephromegaly is a rare condition with many differential diagnoses. We describe the case of a patient with bilateral nephromegaly and spontaneous tumor lysis syndrome secondary to pre-T ALL, who required renal replacement therapy with recovery of renal function following treatment.
Case presentation: A 29-year-old man with an unintentional weight loss of 15 kilograms approximately, intermittent fever (one to two episodes per month), right flank pain radiating to the ipsilateral inguinal region, hyporexia and fatigue. An abdominal ultrasound revealed splenomegaly of 15.7 cm and bilateral nephromegaly (right kidney 144 x 105 x 88 mm and left kidney 143 x 82 x 60 mm). After an extensive approach, etiologies like tuberculosis, human immunodeficiency virus infection, hepatitis B, hepatitis C, toxoplasmosis, cytomegalovirus, herpes virus, and Epstein-Barr were excluded. After retroperitoneal lymph node biopsy, pre-T acute lymphoblastic leukemia and also a spontaneous tumor lysis syndrome were diagnosed. After chemotherapy there was improvement and he presented decrease in renal size is observed by imaging study.
Conclusion
The association between nephromegaly with pre-T acute lymphoblastic leukemia and spontaneous tumor lysis syndrome is very rare. In these cases, a multidisciplinary and integrated approach is required to improve outcomes, especially in terms of disease-free survival and recovery of renal function.
College Students’ Disciplinary Expertise and Their Entrepreneurial Intentions: An Exploratory Study Based on Foreign Language Majors with Experience in Innovation and Entrepreneurship Training Programs
Authors: Dong Xuyang , Fang Nan , Lin Jiaxin , Ye Long 
Published: June 2023

Abstract

Taking foreign language majors with experience in innovation and entrepreneurship training program (IETP) as samples, this study investigates the influence of disciplinary expertise on entrepreneurial intention. Based on the theory of planned behavior (TPB), a model was designed to examine the relationships among entrepreneurial intentions, perceived behavioral control, attitude toward entrepreneurship, subjective norms, IETP experience, foreign language self-efficacy and cultural intelligence. The data were collected through questionnaires and Partial least squares structural equation modeling (PLS-SEM) was adopted to test the hypotheses. The results show that: (1) perceived behavioral control and attitude toward entrepreneurship are sound predictors of entrepreneurial intentions but the influence of subjective norms on entrepreneurial intentions is insignificant; (2) IETP experience is directly related with perceived behavioral control and indirectly related with entrepreneurial intentions; (3) indicators of participants’ disciplinary expertise such as foreign language self-efficacy and cultural intelligence are directly related with IETP experience and indirectly related with entrepreneurial intentions. These six variables included in the research model account for 53.4% of the variance of entrepreneurial intentions.
The Economic Benefits of Implementing a Quantity-Based Drug Procurement Policy in Zhejiang Province
Authors: Wu MinJiao , Tang Huilin , Zhang Xihong , Chen Bo , Ye Lingchao , Yang sufeng , Tung TaoHsin , Chen Zhenyu 
Published: June 2023

Abstract
Objective We aimed to evaluate the implementation of China's purchasing with quantity policy and the economic benefits of drug price reduction by analysing the progress of purchasing with quantity and the actual savings in the purchasing cost of a medical group in Zhejiang Province.Methods Retrospective statistical analysis of a medical group for three consecutive years of drug procurement data, combined with the drugs and quantity in purchase and sale agreement, was conducted. Furthermore, the completion of the agreed quantity and the savings in the purchase amount were confirmed.Results The agreed quantity was 100%, and the quantity of some drugs was more than 200%. The purchasing with quantity policy was effectively implemented, and drug costs were significantly reduced.Conclusion The implementation of government-dominated drug procurement bidding and a series of related policies can effectively reduce drug costs.
Second-generation dual-channel visible light optical coherence tomography enables wide-field, full-range, and shot-noise limited human retinal imaging
Authors: Wang Jingyu , Nolen Stephanie , Song Weiye , Shao Wenjun , Wei Yi , Kashani Amir , Yi Ji 
Published: June 2023

Abstract
Visible light optical coherence tomography (VIS-OCT) is an emerging ophthalmic imaging method featuring ultrahigh depth resolution, retinal microvascular oximetry, and distinct scattering contrast in the visible spectral range. The clinical utility of VIS-OCT is hampered by the fundamental trade-off between the imaging depth range and axial resolution, which are determined by the spectral resolution and bandwidth, respectively. While the full potential of VIS-OCT is leveraged by a broad bandwidth, the imaging depth is inversely sacrificed. The effective depth range is further limited, especially in the shorter wavelengths, by the spectrally dependent roll-off of the signal-to-noise ratio (SNR). To address this trade-off, we developed a second-generation (2nd Gen) dual-channel VIS-OCT system with three major advancements including the first linear-in-K VIS-OCT spectrometer to decrease the roll-off, reference pathlength modulation to expand the imaging depth range, and per-A-line noise cancellation to remove excess noise, Due to these unique designs. this system achieves 7.2 dB roll-off over the full 1.74 mm depth range (water) with shot-noise limited performance. The system uniquely enables > 60° wide-field imaging which would allow simultaneous imaging of the peripheral retina and optic nerve head, as well as ultrahigh 1.3 µm depth resolution (water). Benefiting from the additional near-infrared (NIR) channel of the dual-channel design, this system was compatible with Doppler OC T and OCT angiography (OCTA). The comprehensive structure-function measurements enabled by this second-generation dual-channel VIS-OCT system is a significant advance towards adoption of VIS-OCT in clinical applications.
A improved fuzzy TOPSIS based on centroid of fuzzy numbers
Authors: Mun Jong-Hui , Mun Kyong-Ho 
Published: June 2023

Abstract
Fuzzy multicriteria decision making (fuzzy MCDM) problem has attracted the attention of many researchers in connection with its important interest in various fields. Fuzzy TOPSIS (Technique for order preference by similarity to ideal solution) is one of the most widely used fuzzy MCDM methods, which is constantly evolving due to changes in the process of weight determination, the aggregation process, and the standardization method.
In this paper, we propose a improved fuzzy TOPSIS method to solve the fuzzy MCDM problem under the condition of group decision making. In this method, we determined the weights of the criteria according to the direct evaluation method by triangular fuzzy numbers and used a nonlinear normalization method.
Also, we evaluate the alternatives in terms of weighted relative closeness coefficient as well as the distance from positive and negative ideal solutions is solved based on the centroid concept of fuzzy numbers.
This method not only can overcome certain drawbacks inherent in existing fuzzy TOPSIS methods, but can also be widely applied in various fields. The proposed method is illustrated by a detailed numerical example.
Risk Factors for Central Visual Field Progression in Myopic Patients with Primary Open-Angle Glaucoma
Authors: Hung Chien-Wei , Hung Chih-Heng , Tu Pei-Ning , Chen Yi-Chun 
Published: June 2023

Abstract
Myopia was linked to the development and progression of primary open-angle glaucoma (POAG), on top of causing early central visual field (VF) involvement. The present study investigated the risk factors for central VF progression in myopic patients with POAG. We included 69 myopic patients with POAG with at least 3 years of follow-up and 5 reliable VF examinations. The rates of mean threshold changes at various VF regions were analyzed and clinical variables associated with faster central VF progression were identified using multivariate logistic regression. The presence of disc hemorrhage was associated with faster global (P = 0.013) and central VF progression (P = 0.046). Those tilted discs with lesser absolute degree of optic disc rotation were associated with faster VF progression in inferior-central region (P = 0.040). Comparative results showed those with < 15 degrees of optic disc rotation had faster VF progression in the inferior-central region (P = 0.017). In myopic patients with POAG, the presence of DH and those tilted discs with lesser optic disc rotation were associated with faster central VF progression.
Sexual dimorphisms in body proportions of Masai giraffe
Authors: Cavener Douglas R. , Wu-Cavener Lan , Bond Monica L. , Lohay George G. , Hou Xiaoyi , Pearce David L. , Lee Derek E. 
Published: June 2023

Abstract
Giraffes exhibit a large sexual dimorphism in stature and body mass. Whether sexual dimorphisms also exist in relative body proportions of the axial and appendicular skeleton has been debated, particularly regarding the evolution of the giraffe’s iconic long neck. We measured and analyzed the relative anatomical proportions of the neck, legs, and body trunk of the Masai giraffe (G.c. tippelskirchi) in captive and wild populations. We found that female Masai giraffes have proportionally longer necks relative to their forelegs than males. Moreover, the female body trunk is proportionally longer whereas male foreleg length and neck width are proportionally greater. The sexual dimorphisms in body proportions were found in both captive and wild Masai giraffes suggesting that these differences are genetically determined. We speculate that the proportionally longer female neck is to compensate for females’ overall shorter stature to expand access to forage and their longer trunk is to accommodate fetal growth. Males’ longer forelegs, which contribute to the overall anterior body stature, likely provides some advantage in physical intrasexual competitions. Differences in the proportions of major body components define sex phenotypes, but several male and female giraffes display opposite-sex phenotypes with a significantly higher level of discordancy seen in captive males. We speculate that body proportion sexual dimorphisms are maintained in the wild by natural and/or sexual selection, but in captivity selection is relaxed because of human-altered mating and feeding behavior resulting in a higher proportion of sexual dimorphism discordances.