bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical Features Associated With Rate of Fractures in Patients With Systemic Sclerosis: A US Cohort Study
Authors: Rogers Bliss , Famenini Sina , Perin Jamie , Danila Maria I. , Wipfler Kristin , Michaud Kaleb , McMahan Zsuzsanna H. 
Published: April 2023

ObjectiveSystemic sclerosis (SSc) is associated with several specific risk factors for fracture due to the complications of the disease and related medications. The present study was undertaken to examine the relationship between SSc‐associated clinical features and fracture rate in a large US cohort.MethodsParticipants with SSc in FORWARD, The National Databank for Rheumatic Diseases, were included (1998–2019). Age‐ and sex‐matched individuals with osteoarthritis (OA) from the same database were included as comparators. The primary end point was self‐reported major osteoporotic fracture. Cox proportional hazards models were used to study the associations between risk factors and fractures.ResultsThe study included 922 individuals (SSc patients, n = 154; OA patients, n = 768). Eighty‐seven percent were female, with a mean age of 57.8 years. Fifty‐one patients developed at least 1 fracture during a median of 4.2 years (0.5–22.0 years) of follow‐up. Patients with SSc had more frequent fractures compared to OA comparators (hazard ratio [HR] 2.38 [95% confidence interval (95% CI) 1.47–3.83]). Among patients with SSc, a higher Rheumatic Disease Comorbidity Index score (HR 1.45 [95% CI 1.20–1.75]) and a higher Health Assessment Questionnaire disability index score (HR 3.83 [95% CI 2.12–6.93]) were associated with more fractures. Diabetes mellitus (HR 5.89 [95% CI 2.51–13.82]) and renal disease (HR 2.43 [95% CI 1.10–5.37]) were independently associated with fracture among SSc patients relative to SSc patients without these comorbidities.ConclusionOur findings highlight factors associated with fracture among patients with SSc. Disability as measured by the HAQ DI is a particularly strong indicator of fracture rate in SSc. Improving SSc patients’ functional status, where possible, may lead to better long‐term outcomes.
A new application of the hardware in the loop test of the min–max controller for turbofan engine fuel control
Authors: Davoodi M. , Bevrani H. 
Published: April 2023

AbstractThis article performs a novel hardware test application on the min–max algorithm to control a two‐axis turbofan engine's fuel with a high bypass ratio. In this technique the microcontroller uses a nonlinear model based on the min–max algorithm to control the turbofan's fuel consumption. The min–max control method precisely provides the desired thrust while meeting the engine's physical and operational limitations. By setting the engine's limits appropriately, a surge is prevented from happening due to overheating of the turbine. As a proof of concept, the proposed fuel control algorithm is verified using an Intel Addison's Arduino microcontroller connected to a computer. The implemented hardware is examined by incorporating it into a typical control loop test and monitored via a computer. The achieved results indicate fast time response and algorithm flexibility in simulation modes. The test results confirm the precision and proper implementation of the proposed min–max control algorithm. In addition, the suggested min–max control algorithm can be applied to realize restrictions such as the rotational speed and the outlet pressure of the high‐pressure compressor under the required conditions.
Self‐Reinforced Hydrogel‐Based Skin‐Contactable Flexible Electronics for Multimodal Electrophysiological Signal Monitoring and Emergency Alarming System
Authors: Liu Rongjun , Wang Tengjiao , Li Gangfeng , Fan Zhuoyao , Zhou Qian , Wang Kun , Li Peng , Huang Wei 
Published: April 2023

AbstractInherently tissue‐like feature and multifunctional property of hydrogels make themself excellent materials for flexible electronics. However, conventional hydrogels with insufficient mechanical strength and poor fatigue resistance are damaged or lose service stability when subjected to alternating stress. Herein, self‐reinforced hydrogels are fabricated from elaborately designed ionic conductive hydrogels after repetitive sweat soak‐dehydration (SSD) treatment. The tensile strength of self‐reinforced hydrogels is improved to 930 from 480 kPa and exhibits insensitivity to crack propagation in any direction after 6 SSD treatment cycles. In addition, the self‐reinforced hydrogels show excellent skin friendliness compared with commercial wearable materials in a skin‐compatibility mouse model. Bringing together those advantages, various skin‐contactable flexible electronics are fabricated utilizing the self‐reinforced hydrogels and an emergency alarming system for acute myocardial infarction caused cardiogenic shock is also integrated that is expected to help potential patients in accidents.
Giant Anomalous Hall and Nernst Conductivities in Magnetic All‐d Metal Heusler Alloys
Authors: Tanzim Mohammad Farhan , Fortunato Nuno , Samathrakis Ilias , Xie Ruiwen , Opahle Ingo , Gutfleisch Oliver , Zhang Hongbin 
Published: April 2023

AbstractAll‐d Heuslers are a category of novel compounds combining versatile functionalities such as caloric responses and spintronics with enhanced mechanical properties. Despite the promising transport properties (anomalous Hall (AHC) and anomalous Nernst (ANC) conductivities) shown in the conventional Co2XY Heuslers with p‐d hybridization, the all‐d Heuslers with only d‐d hybridization open a new horizon to search for new candidates with outstanding transport properties. In this work, the AHC and ANC are evaluated for thermodynamically stable ferro/ferri‐magnetic all‐d‐metal regular Heusler compounds based on high‐throughput first‐principles calculations. It is observed that quite a few materials exhibit giant AHCs and ANCs, such as cubic Re2TaMn with an AHC of 2011 S cm‐1, and tetragonal Pt2CrRh with an AHC of 1966 S cm‐1 and an ANC of 7.50 A m‐1K‐1. Comprehensive analysis on the electronic structure reveals that the high AHC can be attributed to the occurrence of the Weyl nodes or gapped nodal lines in the neighborhood of the Fermi level. The correlations between such transport properties and the number of valence electrons are also thoroughly investigated, which provides a practical guidance to tailor AHC and ANC via chemical doping for transverse thermoelectric applications.
Modular Design for Versatile Broadband Polarizing Metasurfaces with Freely Switching Functions
Authors: Song Kun , Gong Xuejian , Cao Yunshan , Chen Qiang , Ji Ruonan , Liu Yahong , Zhao Xiaopeng , Zhou Jiangfeng , Navarro‐Cía Miguel 
Published: April 2023

AbstractPolarization is a fundamental property of electromagnetic waves that plays a key role in many physical phenomena and applications. Schemes to manipulate it are revisited with the emergence of metasurfaces, which have brought multi‐functionalities straightforwardly. However, this has come at the expense of design complexity that relies strongly on field theory. Here, an ingenious strategy of modular design is proposed to construct subwavelength multifunctional polarization control devices. Chiral metasurfaces with different handedness are first proposed and regarded as modules. The versatile polarization controller can thus be obtained with the combination of different modules. These experiments demonstrate that the well‐designed polarization controller possesses reconfigurable functionality, and various broadband polarization and amplitude regulation functions with high efficiency including arbitrary linear polarization rotation, asymmetric transmission effect, neutral‐density‐like filter, polarization beam splitter, etc., can be readily realized just by changing the cascaded modules. The physical mechanisms of the versatile polarization controller and chiral metasurface modules are both guaranteed by the Fabry–Pérot‐like resonances, which are theoretically verified via the transfer matrix method. It is envisioned that the modular concept will be of great benefit to designing compact multifunctional polarization controllers.
Garnet Electrolyte‐Based Integrated Architecture for High‐Performance All‐Solid‐State Lithium‐Oxygen Batteries
Authors: Gu Zhi , Xin Xing , Xu Zelin , He Jun , Wu Jinghua , Sun Yong , Yao Xiayin 
Published: April 2023

AbstractAll‐solid‐state lithium‐oxygen (Li‐O2) battery is considered to be a promising next‐generation energy storage system to address the issues related to low specific capacity, unsafety and unstable electrochemistry that exist in conventional liquid Li‐O2 batteries. However, current solid‐state Li‐O2 batteries still encounter the challenge of high impedance at the electrode/electrolyte interface. In addition, the deficiency of triple‐phase boundaries (containing Li+, e− and O2) limits the active sites for electrochemical reaction in the battery cathode. Herein, an integrated architecture based on a garnet electrolyte Li6.4La3Zr1.4Ta0.6O12 (LLZTO) and a porous composite cathode for high‐performance all‐solid‐state Li‐O2 batteries is developed. The unique internal structure effectively reduces the interfacial impedance of the battery, provides a large number of active sites at triple‐phase boundaries and increases the electrochemical stability. As a result, the obtained batteries can deliver a superior high full discharge capacity of 13.04 mA h cm−2 and an excellent cyclic performance (86 cycles). In addition, X‐ray photoelectron spectroscopy, differential electrochemical mass spectrometry and theoretical calculations further demonstrate the effectiveness of this design in enhancing the interfacial performance, electrochemical performance, and stability of the battery. This study is thus expected to facilitate practical applications for truly all‐solid‐state Li‐O2 batteries, and even for other systems of metal‐oxygen (air) batteries.
Simultaneous CO2and H2O Activation via Integrated Cu Single Atom and N Vacancy Dual‐Site for Enhanced CO Photo‐Production
Authors: Duan Youyu , Wang Yang , Zhang Weixuan , Zhang Jiangwei , Ban Chaogang , Yu Danmei , Zhou Kai , Tang Jinjing , Zhang Xu , Han Xiaodong , Gan Liyong , Tao Xiaoping , Zhou Xiaoyuan 
Published: April 2023

AbstractPhotocatalytic conversion of CO2into fuels using pure water as the proton source is of immense potential in simultaneously addressing the climate‐change crisis and realizing a carbon‐neutral economy. Single‐atom photocatalysts with tunable local atomic configurations and unique electronic properties have exhibited outstanding catalytic performance in the past decade. However, given their single‐site features they are usually only amenable to activations involving single molecules. For CO2photoreduction entailing complex activation and dissociation process, designing multiple active sites on a photocatalyst for both CO2reduction and H2O dissociation simultaneously is still a daunting challenge. Herein, it is precisely construct Cu single‐atom centers and two‐coordinated N vacancies as dual active sites on CN (Cu1/N2CV‐CN). Experimental and theoretical results show that Cu single‐atom centers promote CO2chemisorption and activation via accumulating photogenerated electrons, and the N2CV sites enhance the dissociation of H2O, thereby facilitating the conversion from COO* to COOH*. Benefiting from the dual‐functional sites, the Cu1/N2CV‐CN exhibits a high selectivity (98.50%) and decent CO production rate of 11.12 µmol g−1 h−1. An ingenious atomic‐level design provides a platform for precisely integrating the modified catalyst with the deterministic identification of the electronic property during CO2photoreduction process.
Non‐Interpenetrated 3D Covalent Organic Framework with Dia Topology for Au Ions Capture
Authors: Liu Minghao , Kong Hui‐Yuan , Bi Shuai , Ding Xuesong , Chen George Zheng , He Jun , Xu Qing , Han Bao‐Hang , Zeng Gaofeng 
Published: April 2023

AbstractThe 3D covalent organic frameworks (COFs) have attracted considerable attention owing to their unique structural characteristics. However, most of 3D COFs have interpenetration phenomena, which will result in decreased surface area and porosities, and thus limited their applications in molecular/gas capture. Developing 3D COFs with non‐fold interpenetration is challenging but significant because of the existence of non‐covalent interactions between the adjacent nets. Herein, a new 3D COF (BMTA‐TFPM‐COF) with dia topology and non‐fold interpenetration for Au ion capture is first demonstrated. The constructed COF exhibits a high Brunauer–Emmett–Teller surface area of 1924 m2 g−1, with the pore volume of 1.85 cm3 g−1. The high surface area and abundant cavities as well as the abundant exposed CN linkages due to the non‐interpenetration enable to absorb Au3+ with high capacity (570.18 mg g−1), selectivity (99.5%), and efficiency (68.3% adsorption of maximum capacity in 5 min). This work provides a new strategy to design 3D COFs for ion capture.
Microfluidic Templated Stem Cell Spheroid Microneedles for Diabetic Wound Treatment
Authors: Wu Xiangyi , Huang Danqing , Xu Ye , Chen Guopu , Zhao Yuanjin 
Published: April 2023

AbstractWound dressing patches based on stem cells have demonstrated promising potential in the treatment of diabetic wounds, while their capabilities in the maintenance of cell stemness, effective exchange of cellular substance, and precise targeting of the stem cells remain to be promoted. Here, a novel stem cell spheroid loaded microneedle (MN@SPs) patch is presented using microfluidic templating technology. By leveraging the precise fluid manipulation capabilities of the microfluidic template, stem cell spheroids (SPs) with uniform size can be generated in situ. The resulting SPs exhibit advanced viability and cell functions, as evidenced by the overexpressed genes related to extracellular matrix organization and angiogenesis. By loading these SPs into the microneedles (MNs), the platform enables the precise delivery and exchange of multiple active substances, which contribute to advanced neovascularization, collagen deposition, and tissue reconstruction of diabetic wounds. Overall, this microfluidic‐engineered stem cell therapy platform demonstrates significant promise in promoting wound healing.
Supramolecular Ionogels Tougher than Metals
Authors: Li Weizheng , Li Lingling , Liu Ziyang , Zheng Sijie , Li Qingning , Yan Feng 
Published: April 2023

AbstractCommon natural and synthetic high‐strength materials (such as rubber, plastics, ceramics, and metals) undergo the occurrence of poor deformability. Achieving high strength and large deformation simultaneously is a huge challenge. Herein, high‐strength ionogels are developed through the synergy of force‐induced crystallization and halometallate ionic liquid created supramolecular ionic networks. The prepared poly(vinyl alcohol)/halometallate ionic liquid ionogels show excellent mechanical properties, including ultimate fracture stress (63.1 ± 2.1 MPa), strain (5248 ± 113%), and unprecedented toughness (1947 ± 52 MJ m−3), which is much higher than that of most metals and alloys. Furthermore, the ionogels can achieve reversibility by water to realize green recovery and restoration of damaged mechanical properties.
Post‐Maturation Reinforcement of 3D‐Printed Vascularized Cardiac Tissues
Authors: Silberman Eric , Oved Hadas , Namestnikov Michael , Shapira Assaf , Dvir Tal 
Published: April 2023

AbstractDespite advances in biomaterials engineering, a large gap remains between the weak mechanical properties that can be achieved with natural materials and the strength of synthetic materials. Here, a method is presented for reinforcing an engineered cardiac tissue fabricated from differentiated induced pluripotent stem cells (iPSCs) and an extracellular matrix (ECM)‐based hydrogel in a manner that is fully biocompatible. The reinforcement occurs as a post‐fabrication step, which allows for the use of 3D‐printing technology to generate thick, fully cellularized, and vascularized cardiac tissues. After tissue assembly and during the maturation process in a soft hydrogel, a small, tissue‐penetrating reinforcer is deployed, leading to a significant increase in the tissue's mechanical properties. The tissue's robustness is demonstrated by injecting the tissue in a simulated minimally invasive procedure and showing that the tissue is functional and undamaged at the nano‐, micro‐, and macroscales.
Oxide Supported Cobalt Catalysts for CO2 Hydrogenation to Hydrocarbons: Recent Progress
Authors: Scarfiello Canio , Pham Minh Doan , Soulantica Katerina , Serp Philippe 
Published: April 2023

AbstractCarbon capture and utilization represents a promising strategy to meet the global energy and climate goals. Under specific conditions, CO2 catalytic hydrogenation with renewable H2 can transform waste CO2 into a chemical feedstock for added‐value energy carriers and chemicals. CO2‐Fischer–Tropsch synthesis‐based‐hydrocarbons should contribute to the creation of a circular carbon economy with a significant impact on anthropogenic emission into the atmosphere. This review summarizes the progress achieved toward the single‐step hydrogenation of CO2 to long‐chain hydrocarbons over oxide‐supported Co‐based catalysts. Mechanistic aspects are discussed in relation to thermodynamic and kinetic limitations. The main parameters that must be taken into consideration to increase the activity and the selectivity toward compounds of two or more carbon atoms (C2+) are discussed in detail: cobalt active phase, support and metal‐support interfaces, and promoters. Finally, particular focus is dedicated to the role of reducible oxide supports and their surface defects on the activation of CO2, as well as on the regulation and evolution of metal‐support interactions.
Electrical and Optical Modulation of a PEDOT:PSS‐Based Electrochemical Transistor for Multiple Neurotransmitter‐Mediated Artificial Synapses
Authors: Matrone Giovanni Maria , Bruno Ugo , Forró Csaba , Lubrano Claudia , Cinti Stefano , van de Burgt Yoeri , Santoro Francesca 
Published: April 2023

AbstractNeuromorphic systems that display synaptic conditioning based on biochemical signaling activity have recently been introduced in the form of artificial synapses that are model devices to develop tissue‐interfaced platforms. In this regard, biohybrid synapses promise adaptive neuron‐integrated functions. However, these systems suffer from both molecular cross‐talk as biological neural circuits signal transmission typically involves more than one neuromodulator, and unstable electronics wirings as complex architectures are required to interface the tissues. Moreover, whilst novel spiking circuits can work as artificial neurons, they only recreate the biological electrical signaling pathway while electrochemical signal transduction is required for inter‐neuron communication. As such, artificial chemically‐mediated synapses are essential to perform memory/learning computing functions. Herein, an electrochemical neuromorphic organic device (ENODe) working as an artificial synapse that overcomes electrochemical and readout interferences while it emulates two neurotransmitters synaptic weight modulation and their recycling machinery at the synaptic cleft is shown. Neuronal short‐ and long‐term plasticity are replicated by transducing two separate neurotransmitter‐mediated chemical signals into reversible and nonreversible variations of PEDOT:PSS conductance. By exploiting the electrochromic properties of PEDOT:PSS, an alternative optical monitoring strategy is introduced which promises stable multidevice readout from complex bio‐hybrid interfaces. The platform emulates high‐order biological processes such as intrinsic forgetting, memory consolidation, and neurotransmitter co‐modulation. These brain‐inspired functionalities herald the development of tissue‐integrated neuromorphic systems that combine spiking (electrical neurons) and nonspiking (electrochemical synapses) elements, thus envisioning prosthetic bridges for neural engineering and regenerative medicine.
Excitation‐Dependent Long Afterglow Room‐Temperature Phosphorescence Material Activated by Doping Boric Acid Matrix
Authors: Deng Junjie , Guan Zhihao , Fu Donglei , Zheng Yuewei , Chen Zhengjie , Li Houbin , Liu Xinghai 
Published: April 2023

AbstractRoom‐temperature phosphorescence (RTP) materials are normally prepared by doping guest materials into space‐limited host materials to inhibit nonradiative decay. This work aims to prepare a long afterglow excitation‐dependent emission RTP material by doping a small amount of 4‐carboxyphenylboronic acid into the boric acid matrix, followed by heat‐treating. The calculation of density functional theory shows that the electron cloud distribution and electron transfer trend of the selected material reduces the energy requirement to excite the RTP properties of the obtained materials. The obtained RTP materials can be excited by UV light at 310 and 365 nm for dark blue and green phosphorescence emission, respectively. The results demonstrate the long phosphorescence lifetimes of 1.97 and 0.62 s and the high absolute photoluminescence quantum yields of 17.4% and 15.6%. These results show that the obtained RTP materials have potential prospects as information coding and phosphorescent anti‐counterfeiting.
Recent Progress in Synthetic Applications of Cyclic Hypervalent Iodine(III) Reagents
Authors: Yoshimura Akira , Saito Akio , Zhdankin Viktor V. 
Published: April 2023

AbstractHypervalent iodine compounds have found broad application in modern organic chemistry as reagents and catalysts. Cyclic hypervalent iodine reagents based on the benziodoxole heterocyclic system have higher stability compared to their acyclic analogues, which makes possible the preparation and safe handling of the reagents with special ligands such as azido, cyano, and trifluoromethyl groups. Numerous iodine‐substituted benziodoxole derivatives have been prepared and utilized as reagents for transfer of the substituent on hypervalent iodine to organic substrate. Reactions of these reagents with organic substrates can be performed under metal‐free conditions, in the presence of transition metal catalysts, or using photocatalysts under photoirradiation conditions. In this review, we focus on the most recent synthetic applications of cyclic hypervalent iodine(III) reagents with the following ligands: N3, NHR, CN, CF3, SCF3, OR, OAc, ONO2, and C(=N2)CO2R. The review covers literature published mainly in the last 5 years.
3D Printed Electromyography Sensing Systems
Authors: Su Haotian , Moeinnia Hadi , Kim Woo Soo 
Published: April 2023

AbstractElectromyography (EMG) has been widely used in robotics and biomedical applications for sensing and diagnostic purposes. Because of the complex shape of human limbs and the uneven and flexible surface of the human skin, EMG sensing often faces the challenge of stable signal detection. As manufacturing technology advances, additive manufacturing has shown its potential to improve the existing EMG sensing system further. 3D printing technologies offer the advantage of custom fabrication to fit the designated locations of EMG detection. 3D printing also provides flexible and stretchable features, which allow for a comfortable user experience. This paper presents the recent development of novel 3D‐printed EMG sensing systems. The process of EMG signal detection is compared with the standard system. The corresponding applications with 3D‐printed sensing systems in different fields of study are also discussed. Finally, by reviewing the state‐of‐the‐art technology, the future of 3D printing in EMG sensing and the challenges facing the field are discussed.