bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Unintended Consequences of “Lack of Supervision” Child Neglect Laws: How Developmental Science Can Inform Policies about Childhood Independence and Child Protection
Authors: Flynn Rachel M. , Shaman Nicholas J. , Redleaf Diane L. 
Published: June 2023

AbstractPolicies and programs designed to serve children and families are sometimes misaligned with developmental science research. Broad child neglect reporting laws, first adopted by the United States in 1974, have led to families being prosecuted by child protection authorities for allowing children to participate in everyday age‐appropriate activities unsupervised. In this report we describe the challenges of defining child neglect and outline the current landscape of neglect laws in the United States. We then provide a broad overview of some of the developmental milestones children need to reach to participate in unsupervised activities and the benefits of independent activities on child development. Children can often accomplish tasks at a much younger age than law, parents, and caregivers in the U.S. believe. We then turn to the literature from across the world and argue that culture, not innate ability, drives much of the variation in the age at which children can do things on their own. Finally, we make recommendations to parents, caregivers, legislators, advocates, and developmental scientists to better align practice with research. This is a social justice issue that should resonate across party, racial, and class lines. Developmental scientists are needed as advocates and advisors on policies impacting children and families, especially child neglect laws.
Number of zero-modes on magnetized T4/ZN orbifolds analyzed by modular transformation
Authors: Kikuchi Shota , Kobayashi Tatsuo , Nasu Kaito , Takada Shohei , Uchida Hikaru 
Published: June 2023

Abstract
We study fermion zero-mode wavefunctions on T4/ZN orbifold with background magnetic fluxes. The number of zero-modes is analyzed by use of Sp(4, ℤ) modular transformation. Conditions needed to realize three generation models are clarified. We also study parity transformation in the compact space which leads to better understanding of relationship between positive and negative chirality wavefunctions.
Stress–strain parameter prediction method for AWJ technology from surface topography
Authors: Valíček Jan , Harničárová Marta , Kušnerová Milena , Palková Zuzana , Kopal Ivan , Borzan Cristina , Czán Andrej , Mikuš Rastislav , Kadnár Milan , Duer Stanislaw , Šepelák Vladimír 
Published: June 2023

Abstract
The presented publication is based on the interaction of the material core and its surface during the machining process with a hydro abrasive flexible cutting tool (AWJ). In the AWJ technology, a cold cut is generated; therefore, there are no thermal stresses on the newly formed surface and, consequently, no significant internal and residual stresses. The cut is identifiable by directly measurable parameters: depth of cut, deviation of the cut path from the normal plane, and surface roughness. These geometric parameters are interdependent at each cut zone point and simultaneously dependent on a newly proposed, indirectly measurable material parameter, Kplmat. Although the deviation angle of the cutting path from the normal plane increases with increasing depth of cut, the ratio of the “material plasticity” Kplmat and the surface roughness Ra of the cutting surface remains equivalent to the ratio of the depth of cut and the deviation of the cutting path from the normal plane. Based on the proposed concept, an entirely new approach to the problem of material surface integrity is presented by the method of identification of mechanical equivalents and their functional transformation. The solution to the subject problem is based on the fact that the technological process of machined material decomposition specifically and identically “copies” the surface properties of the material, i.e. records its technological inheritance. The material properties can then be “read retrospectively” reliably and accurately using the recording.
Unsupervised [18F]Flortaucipir cutoffs for tau positivity and staging in Alzheimer’s disease
Authors: Quattrini Giulia , Ferrari Clarissa , Pievani Michela , Geviti Andrea , Ribaldi Federica , Scheffler Max , Frisoni Giovanni B , Garibotto Valentina , Marizzoni Moira ,   for the Alzheimer’s Disease Neuroimaging Initiative
Published: June 2023

Abstract
Purpose
Several [18F]Flortaucipir cutoffs have been proposed for tau PET positivity (T+) in Alzheimer’s disease (AD), but none were data-driven. The aim of this study was to establish and validate unsupervised T+ cutoffs by applying Gaussian mixture models (GMM).

Methods
Amyloid negative (A−) cognitively normal (CN) and amyloid positive (A+) AD-related dementia (ADRD) subjects from ADNI (n=269) were included. ADNI (n=475) and Geneva Memory Clinic (GMC) cohorts (n=98) were used for validation. GMM-based cutoffs were extracted for the temporal meta-ROI, and validated against previously published cutoffs and visual rating.

Results
GMM-based cutoffs classified less subjects as T+, mainly in the A− CN (<3.4% vs >28.5%) and A+ CN (<14.5% vs >42.9%) groups and showed higher agreement with visual rating (ICC=0.91 vs ICC<0.62) than published cutoffs.

Conclusion
We provided reliable data-driven [18F]Flortaucipir cutoffs for in vivo T+ detection in AD. These cutoffs might be useful to select participants in clinical and research studies.
SUVmean on baseline [18F]PSMA-1007 PET and clinical parameters are associated with survival in prostate cancer patients scheduled for [177Lu]Lu-PSMA I&T
Authors: Hartrampf Philipp E. , Hüttmann Thomas , Seitz Anna Katharina , Kübler Hubert , Serfling Sebastian E. , Schlötelburg Wiebke , Michalski Kerstin , Rowe Steven P. , Pomper Martin G. , Buck Andreas K. , Eberlein Uta , Werner Rudolf A. 
Published: June 2023

Abstract

Background
Quantification of [68 Ga]-labeled PSMA PET predicts response in patients with prostate cancer (PC) who undergo PSMA-targeted radioligand therapy (RLT). Given the increasing use [18F]-labeled radiotracers, we aimed to determine whether the uptake derived from [18F]PSMA-1007 PET can also identify responders and to assess its prognostic value relative to established clinical parameters.

Methods
We retrospectively analyzed 103 patients with metastatic, castration-resistant PC who were treated with [177Lu]Lu-PSMA I&T. We calculated SUVmean, SUVmax, PSMA-avid tumor volume (TV), and total lesion PSMA (defined as PSMA-TV*SUVmean) on pre-therapeutic [18F]PSMA-1007 PET. Laboratory values for hemoglobin, C-reactive protein (CRP), lactate dehydrogenase (LDH), aspartate aminotransferase (AST), and alkaline phosphatase (AP) were also collected prior to RLT. We performed univariable Cox regression followed by multivariable and Kaplan–Meier analyses with overall survival (OS) serving as endpoint. Last, we also computed a risk factor (RF) model including all items reaching significance on multivariable analysis to determine whether an increasing number of RFs can improve risk stratification.

Results
A total of 48 patients died and median OS was 16 months. On univariable Cox regression, SUVmean, CRP, LDH, hemoglobin, and the presence of liver metastases were significantly associated with OS. On multivariable Cox regression, the following significant prognostic factors for OS were identified: SUVmean (per unit, HR, 0.91; P = 0.04), the presence of liver metastases (HR, 2.37; P = 0.03), CRP (per mg/dl, HR, 1.13; P = 0.003), and hemoglobin (per g/dl, HR, 0.76; P < 0.01). Kaplan–Meier analysis showed significant separation between patients with a SUVmean below or above a median SUVmean of 9.4 (9 vs 19 months, HR 0.57; P = 0.03). Of note, patients with only one RF (median OS not reached) showed longest survival compared to patients with two (11 months; HR 2.43 95% CI 1.07–5.49, P = 0.02) or more than two RFs (7 months; HR 3.37 95% CI 1.62–7.03, P < 0.001).

Conclusion
A lower SUVmean derived from [18F]PSMA-1007, higher CRP, lower hemoglobin, and the presence of liver metastases are associated with reduced OS in patients undergoing RLT. An early RF model also demonstrated that an increasing number of those factors is linked to worse outcome, thereby emphasizing the importance of clinical and imaging parameters for adequate risk stratification.
Treatment optimization by monitoring vancomycin concentration in the serum and cerebrospinal fluid in a child with cystoperitoneal shunt-related infection caused by methicillin-resistant Staphylococcus aureus: a case report and literature review
Authors: Mizuno Shinsuke , Koyama Junji , Kurosawa Hiroshi , Kasai Masashi 
Published: June 2023

Abstract
Background
Cerebral ventricular shunt infections caused by methicillin-resistant Staphylococcus aureus (MRSA), especially strains with elevated minimum inhibitory concentration (MIC) values, have a poor prognosis. Monitoring serum vancomycin (VCM) levels with therapeutic drug monitoring and maintaining high VCM concentrations in the cerebrospinal fluid (CSF) are critical to treatment success. However, there have been a few reports about the CSF penetration and the pharmacokinetics of VCM in children.

Case presentation
Here, we report the case of a pediatric patient with cysto-peritoneal shunt-related meningitis caused by MRSA with an MIC of 2 μg/mL. The adequate VCM concentration was maintained by monitoring the VCM concentration in the CSF via the external ventricular drain, and frequent blood taking was avoided. VCM showed a good CSF penetration in our patient, and she was discharged without complications.

Discussion
Therapeutic drug monitoring of VCM concentration in the CSF may result in successful treatment even if MRSA shows a higher MIC. Therapeutic drug monitoring of VCM concentration in the CSF may also reduce the side effects.
Leray Numbers of Tolerance Complexes
Authors: Kim Minki , Lew Alan 
Published: June 2023

AbstractLet K be a simplicial complex on vertex set V. K is called d-Leray if the homology groups of any induced subcomplex of K are trivial in dimensions d and higher. K is called d-collapsible if it can be reduced to the void complex by sequentially removing a simplex of size at most d that is contained in a unique maximal face. Motivated by results of Eckhoff and of Montejano and Oliveros on “tolerant” versions of Helly’s theorem, we define the t-tolerance complex of K, $${\mathcal {T}}_{t}(K)$$

T
t

(
K
)

, as the simplicial complex on vertex set V whose simplices are formed as the union of a simplex in K and a set of size at most t. We prove that for any d and t there exists a positive integer h(t, d) such that, for every d-collapsible complex K, the t-tolerance complex $${\mathcal {T}}_t(K)$$

T
t

(
K
)

is h(t, d)-Leray. As an application, we present some new tolerant versions of the colorful Helly theorem.
Evaluation of the MOVE online exercise programme for young people aged 13–30
Authors: Barnes Ellie , Hillier-Moses Gemma , Murray Helen , Stevinson Clare , Franks Hester A. , Gossage Lucy 
Published: June 2023

Abstract
Purpose
To evaluate the MOVE exercise programme in supporting the recovery of young people affected by cancer.

Methods
Participants in an 8-week exercise rehabilitation programme delivered online by cancer rehabilitation specialists completed self-reported questionnaires at baseline and after programme completion. Assessments included cancer-related fatigue (FACIT fatigue scale) and health-related quality of life (EORTC-QLC-30). Qualitative data were provided through written accounts of participant experiences and underwent content analysis.

Results
Seventy-one participants commenced the exercise rehabilitation programme and 57 completed the programme and provided data for analysis (63% female; median age 22 years). Statistically significant improvements were observed in post-programme scores for all measured outcomes (cancer-related fatigue, quality of life, physical functioning, role functioning, emotional functioning). Content analysis of written experiences generated ten unique codes. The highest frequency codes were enjoyment (n = 34), motivation (n = 14) and fitness (n = 13).

Conclusions
These findings indicate feasibility of delivery, acceptability to patients and physical and psychological benefits of a personalised online exercise rehabilitation programme for young people living with and beyond cancer. Further research involving a control arm and long-term follow-up would be beneficial.

Implications for cancer survivors
These results support the inclusion of a personalised exercise programme as part of cancer rehabilitation for young people living with and beyond cancer.
Improving school children’s understanding of water scarcity with a co-produced book on groundwater in Central Chile
Authors: Vargas-Payera Sofía , Taucare Matías , Pareja Claudio , Vejar Jessica 
Published: June 2023

AbstractWater scarcity is a critical issue worldwide, and Chile is no exception. Since 2010, Central Chile has been enduring an ongoing water crisis due to the coupled effects of a severe drought and the overuse of water resources, especially groundwater. Rural communities have been strongly impacted, mainly because wells from which drinking water is supplied show a dramatic drop in water levels, and some have even dried up. The water scarcity scenario requires the integration of actors and disciplines to increase awareness of groundwater; however, how to make this valuable element visible in society is an issue that remains open to debate. This paper describes and reflects on the process of making educational material about groundwater and water scarcity for children to promote public awareness. Based on transdisciplinary and co-designing processes, this work describes the social perceptions of groundwater among children and community leaders, as well as how scientific information and local knowledge of water scarcity could be integrated into a book for the young population. This research finds that educational projects on groundwater resources increase people’s awareness of the role of this hidden resource in the water cycle. Such projects encourage the creation of grounded and contextualised materials that incorporate the knowledge and experience already present in the communities, increasing public awareness of the role of groundwater and associated water scarcity issues, thereby integrating academia and society. This approach could be a tool to lay the foundations for successfully addressing the water crisis in Chile over generations.
Challenges and opportunities for nutrient circularity: an innovation platform approach
Authors: van der Wiel Bernou Zoë , Neuberger Sabine , Darr Dietrich , Wichern Florian 
Published: June 2023

AbstractTo reduce nutrient losses from the food system, it is necessary to improve biomass management and foster change. Such a change is often hindered by a lack of stakeholder interaction. Therefore, a qualitative case study and a practical application of the innovation platform approach in the Dutch-German border region Rhine-Waal were carried out to determine challenges and opportunities in the agro-food-waste system towards circular nutrient management in a nutrient-saturated and intensive animal production-dominated localized area. Twenty-one actors participated in a half-day workshop. A bottom-up approach was chosen as it increases trust between stakeholders and supports the acceptance of research processes. This study identified opportunities and challenges perceived by stakeholders participating in the innovation platform approach to facilitate a transition towards local circular nutrient management. We observed that challenges and opportunities exist at three levels: the individual actor’s level, the system level and the interconnection of the system with its wider environment. With a variety of stakeholders from animal and crop production to the food processing industry being present in the study area, the current demand and supply of biomass is very diverse. This diversity has been identified as a distinct opportunity for the establishment of a biomass exchange network in the area. However, information on demand and supply of nutrients between actors is currently scattered and information sharing hindered by the lack of direct monetary benefits. The lessons learned using the innovation platform approach are a first step towards improving nutrient circularity at a localized scale in nutrient-saturated areas.
Experiences, Knowledge Gaps and Information Needs of Women in Australia with Transfusion Dependent Thalassaemia in Regard to Fertility and Pregnancy
Authors: Matthiesson Hannah K , Berdoukas Vasili , Briganti Esther M 
Published: June 2023

Abstract
Objectives
Transfusion dependent β-thalassaemia can have significant effects on fertility and is also associated with significant risks in pregnancy. However, little is known about the perspectives of women living with the condition with regards to reproductive issues. The aim of this study was to assess the experience, knowledge and information needs of Australian women living with transfusion dependent β-thalassaemia in relation to fertility and pregnancy.

Methods
A cross sectional study using an online anonymous survey, self-administered through REDCap, addressing key issues related to the experience, knowledge and information needs of women with transfusion dependent β-thalassaemia. Descriptive and inferential analysis was conducted using STATA.

Results
Sixty participants were included in the analysis. Two-thirds of sexually active, pre-menopausal women were using contraception. Just under half of the participants who were sexually active had children and half had required some form of assisted reproductive technology to achieve a pregnancy. Less than half identified the importance of contraception as part of ensuring optimised pre-pregnancy care, and less than half had accessed pre-pregnancy care. Although there was good understanding of the increased risk of infertility and pregnancy complications, the specific risks and causes of these risks were poorly understood. Around half of the participants indicated they wanted more information on these medical issues.

Conclusions for practice
Our study demonstrated significant concerns and knowledge gaps in Australian women with transfusion dependent β-thalassaemia with regards to disease-specific issues related to fertility and pregnancy, and a desire for related patient information.
Regularity and symbolic defect of points on rational normal curves
Authors: Jafarloo Iman Bahmani , Malara Grzegorz 
Published: June 2023

AbstractIn this paper we study ideals of points lying on rational normal curves defined in projective plane and projective 3-space. We give an explicit formula for the value of Castelnuovo–Mumford regularity for their ordinary powers. Moreover, we compare the m-th symbolic and ordinary powers for such ideals in order to show whenever the m-th symbolic defect is non-zero.
Effect of Volatile Species on Chemical Vapour Deposition of SiO2 During Corrosion of Chromia- and Alumina-Formers
Authors: Nguyen Thuan Dinh , Zhang Jianqiang , Young David J. 
Published: June 2023

AbstractSilicon-bearing vapour at low pressure was used to deposit SiO2 during exposure of pure chromium, Fe-30Cr (wt.%) and Kanthal APM alloy to an Ar-10H2O-0.1HCl mixture (vol.%) at 650 °C. Pure Cr formed porous chromia blades on top of a polycrystalline Cr2O3 scale containing SiO2. A model Fe-30Cr alloy formed a scale consisting of a thick, amorphous (Cr,Si)Ox outer layer and a thin, polycrystalline Cr2O3 inner layer. Kanthal alloy formed a thin scale containing a Si-rich oxide outer layer and an inner layer of Fe, Cr, and Al oxides. Amorphous (Cr,Si)Ox nodules formed locally on top of (Cr,Fe)23C6 precipitates at the Kanthal surface.
“No one has a solution, madam”: Experiences of Soweto township secondary school teachers teaching human rights education
Authors: Munongi Lucia 
Published: June 2023

Abstract
This article reports on the experiences of secondary school teachers teaching human rights education in Soweto township in South Africa. The study was anchored in phenomenological design and adopted a qualitative research approach. Twelve participants from four urban public secondary schools in Soweto township were sampled. Data were collected through semi-structured individual interviews. Findings revealed that the participants’ experiences were negative due to a lack of teaching resources, a lack of training to teach human rights education, and a lack of support from district officials. However, more positively, participants viewed themselves as having a significant role in teaching human rights education despite their challenges. Based on the findings, the article suggests more support from different stakeholders, such as the Department of Education, the South African Police Services (SAPS), human rights organizations, and other non-governmental organizations in relation to teacher training and teaching resources for the effective teaching of human rights education.
Proof Systems for Super- Strict Implication
Authors: Gherardi Guido , Orlandelli Eugenio , Raidl Eric 
Published: June 2023

AbstractThis paper studies proof systems for the logics of super-strict implication $$\textsf{ST2}$$

ST
2

–$$\textsf{ST5}$$

ST
5

, which correspond to C.I. Lewis’ systems $$\textsf{S2}$$

S
2

–$$\textsf{S5}$$

S
5

freed of paradoxes of strict implication. First, Hilbert-style axiomatic systems are introduced and shown to be sound and complete by simulating $$\textsf{STn}$$
STn
in $$\textsf{Sn}$$
Sn
and backsimulating $$\textsf{Sn}$$
Sn
in $$\textsf{STn}$$
STn
, respectively (for $${\textsf{n}} =2, \ldots , 5$$

n
=
2
,
…
,
5

). Next, $$\textsf{G3}$$

G
3

-style labelled sequent calculi are investigated. It is shown that these calculi have the good structural properties that are distinctive of $$\textsf{G3}$$

G
3

-style calculi, that they are sound and complete, and it is shown that the proof search for $$\mathsf {G3.ST2}$$

G
3
.
ST
2

is terminating and therefore the logic is decidable.
Role of organisational readiness and stakeholder acceptance: an implementation framework of adaptive learning for higher education
Authors: Mirata Victoria , Bergamin Per 
Published: June 2023

AbstractDespite its advantages and potentials, the extent of the implementation of adaptive learning remains limited. Recent studies identified the critical determinants associated with its scaled implementation and proposed various frameworks and strategies to support it. However, little has been done to identify the empirical relationships between such determinants, the strategies for addressing them, and a scaled implementation as the desired outcome. Identifying such relationships can however help elucidate the processes involved in the implementation process of adaptive learning and, therefore, better explain the reasons for its slow implementation. The current study aims to identify the relationships between critical factors associated with the successful implementation of adaptive learning, strategies that address such factors, and the desired outcomes. Based on the identified relationships, the study presents an empirically supported implementation framework for adaptive learning. We used the secondary analysis of qualitative data, which were previously collected from 51 participants in an international Delphi study conducted in two universities in Switzerland and South Africa. For coding, we used inductive coding techniques suitable for identifying connections (e.g., causal relationships) between the identified factors. We conclude by turning the attention of implementation researchers and educational leaders to the key role of organisational readiness and the stakeholder acceptance of adaptive learning during the implementation process.