bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interkulturelle Kompetenzen im Gesundheitswesen durch Fort- und Weiterbildungen fördern
Authors: Dimitrova Desislava , Sehouli Jalid 
Published: September 2023

ZusammenfassungDie Akzeptanz der kulturellen Vielfalt und das Anerkennen und Wertschätzen der Facetten des „Andersseins“ wie Geschlecht, Alter, Berufsgruppe, Krankheitsgruppe, Religion, soziokultureller Hintergrund sowie Migrationsgeschichten sind Grundvoraussetzungen für eine adäquate Kommunikation und Interaktion im Gesundheitswesen. Der Begriff interkulturelle Kompetenz ist multidimensional und umfasst eine Reihe von Eigenschaften und Fähigkeiten, die sowohl emotionale und kognitive Elemente beinhalten als auch die Verhaltensebene berühren. In dem vorliegenden Artikel diskutieren wir die Bedeutung der interkulturellen Kompetenz für das Gesundheitswesen und welche Aspekte der interkulturellen Kommunikation für eine kultursensible medizinische Versorgung besonders relevant sind. Wir berichten außerdem über die Implementierung eines interprofessionellen Fort- und Weiterbildungskonzeptes für die klinische Praxis (IPIKA – „Interprofessionelles und Interkulturelles Arbeiten in Medizin, Pflege und Sozialdienst“).Basis der spezifischen Ansätze zur Verbesserung der interkulturellen Kompetenz sollte die systematische Aus- und Weiterbildung grundsätzlicher kommunikativer Fähigkeiten sein. Dies betrifft nahezu alle Ausbildungscurricula für die medizinischen Professionen. Es ist wichtig zu betonen, dass interkulturelle Kompetenz ein Kern- und Querschnittsthema für alle Beteiligten im Gesundheitssystem darstellt.
The asymptotics of price and strategy in the buyer’s bid double auction
Authors: Williams Steven R. , Zachariadis Konstantinos E. 
Published: September 2023

AbstractIn a model with correlated and interdependent values/costs, we identify for the buyer’s bid double auction the asymptotic distributions of the price and of two order statistics in the first order conditions for optimal bidding/asking, all of which are normal. Substitution of the asymptotic distributions into the first order conditions can permit the solution for approximately optimal bids/asks that provide insight into what is “ first order” in a trader’s strategic decision-making, which has been difficult to obtain through analysis of equilibrium.
Diagnostic value of plasma SIRT1 levels and whole-brain gray matter volume in Parkinson’s disease patients with cognitive impairment
Authors: Li Xiaohuan , Yang Dawei , Ma Jianjun , Wei Wei , Zheng Jinhua , Fan Yongyan , Liang Keke , Shi Xiaoxue , Li Dongsheng , She Zonghan , Qi Xuelin , Chen Siyuan 
Published: September 2023

Abstract
Objective
This study was designed to investigate the diagnostic value of plasma SIRT1 levels and whole-brain gray matter (GM) volume in Parkinson’s disease (PD) patients with cognitive impairment.

Methods
Automated enzymatic analysis was performed to measure plasma SIRT1 levels in 80 healthy controls and 77 PD patients. Motor symptoms and nonmotor symptoms in PD patients were assessed using the corresponding scales. A Siemens MAGNETOM Prisma 3 T MRI scanner was used to acquire images in 35 of 77 PD patients.

Results
Plasma SIRT1 levels in PD patients were lower than those in healthy controls. Plasma SIRT1 levels were negatively correlated with the age, Unified Parkinson’s Disease Rating Scale Part III (UPDRS-III) scores, anxiety, depression, excessive daytime sleepiness (EDS), quality of life, and especially cognitive impairment. Thus, it showed that plasma SIRT1 levels were relevant to visuospatial/executive function, memory, and language. Receiver-operating characteristic (ROC) analysis confirmed that plasma SIRT1 levels had good diagnostic accuracy for PD with anxiety and EDS. Furthermore, plasma SIRT1 levels had a significant positive correlation with GM volume in the whole brain, and ROC analysis confirmed that plasma SIRT1 levels and the total GM volume had good diagnostic accuracy for PD with cognitive impairment.

Conclusions
This study showed that plasma SIRT1 levels were correlated with the nonmotor symptoms of anxiety, depression, EDS, and especially cognitive impairment as well as the total GM volume. Furthermore, the combination of plasma SIRT1 levels and the total GM volume had good diagnostic accuracy for PD with cognitive impairment.
Boosting the visibility of services in microservice architecture
Authors: Tokmak Ahmet Vedat , Akbulut Akhan , Catal Cagatay 
Published: September 2023

AbstractMonolithic software architectures are no longer sufficient for the highly complex software-intensive systems, which modern society depends on. Service Oriented Architecture (SOA) surpassed monolithic architecture due to its reusability, platform independency, ease of maintenance, and scalability. Recent SOA implementations made use of cloud-native architectural approaches such as microservice architecture, which has resulted in a new challenge: the discovery difficulties of services. One way to dynamically discover and route traffic to service instances is to use a service discovery tool to locate the Internet Protocol (IP) address and port number of a microservice. In the event that replicated microservice instances are found to provide the same function, it is crucial to select the right microservice that provides the best overall experience for the end-user. Parameters including success rate, efficiency, delay time, and response time play a vital role in establishing a microservice’s Quality of Service (QoS). These assessments can be performed by means of a live health-check service, or, alternatively, by making a prediction of the current state of affairs with the application of machine learning-based approaches. In this research, we evaluate the performance of several classification algorithms for estimating the quality of microservices using the QWS dataset containing traffic data of 2505 microservices. Our research also analyzed the boosting algorithms, namely Gradient Boost, XGBoost, LightGBM, and CatBoost to improve the overall performance. We utilized parameter optimization techniques, namely Grid Search, Random Search, Bayes Search, Halvin Grid Search, and Halvin Random Search to fine-tune the hyperparameters of our classifier models. Experimental results demonstrated that the CatBoost algorithm achieved the highest level of accuracy (90.42%) in predicting microservice quality.
The corporate legal profession’s role in global corruption: obligations and opportunities for contributing to collective action
Authors: Elliott Jasmine 
Published: September 2023

AbstractKey corruption issues, like lack of transparency in beneficial ownership and money laundering, are inherently transnational. They are facilitated by professional services, like corporate lawyers, who work with various standards, regulations, and global financial flows that can move the proceeds of crime across the world. This paper uses reflective equilibrium to analyze the tensions between the philosophical principles of complicity and collective responsibility and the principles found in the professional role of lawyers in society to reflect on the corporate legal profession’s role in enabling corruption. Furthermore, this paper explores how these tensions can be addressed and how lawyers can be situated in anti-corruption collective action theory and practical collective action initiatives. For example, the legal profession has a collective obligation to maintain and self-patrol the profession’s ethics, primarily through their regulating authorities, and it should be considered to what extent these authorities are promoting anti-corruption standards or reprimanding lawyers who are complicit in corrupt acts. There is also an opportunity for corporate lawyers to use their role in society to develop more collective action initiatives to address issues of transnational corruption, which may include enforcing a higher collective standard in providing advice or advocating for legislators to fix regulations and promote legislation that addresses corrupt practices.
Use of digital self-control tools in higher education – a survey study
Authors: Biedermann Daniel , Kister Stella , Breitwieser Jasmin , Weidlich Joshua , Drachsler Hendrik 
Published: September 2023

AbstractDistractions are ubiquitous in today’s technology-saturated environments, an issue that significantly impacts learning contexts employing digital technologies and yields detrimental effects on learning. Digital self-control tools, which aim to assist users in their efforts to reduce digital distractions, are numerous and readily available. Despite several dedicated empirical studies focusing on specific tools, there remains a notable lack of information regarding their daily use and helpfulness. Furthermore, the sheer variety of these tools prompts questions about their universal helpfulness and the potential influence of individual differences.To address these issues, we surveyed a sample of higher-education students, totaling 273 individuals. These students reported on their media use, satisfaction with learning, and experiences with features of digital self-control tools. Our study’s findings indicate a discrepancy in the perception and awareness of these features; those deemed most helpful are among the least known, and conversely, common features are often perceived as unhelpful.Our research also uncovered a negative correlation between habitual media use and the use of less restrictive features. Another identified issue was constraints on the use of these tools for learning, as platforms often serve dual purposes for both education and entertainment. We delve into these practical problems and propose future research directions to further advance the understanding of digital self-control tools.
Molecular analysis of a Spanish isolate of chili pepper mild mottle virus and evaluation of seed transmission and resistance genes
Authors: Ontañón Clara , Ojinaga Mikel , Larregla Santiago , Zabala Joseba Andoni , Reva Anastasiia , Losa Alba , Heribia Rosario , Bertacca Sofia , Sanahuja Esmeralda , Alfaro-Fernández Ana , Font-San Ambrosio María Isabel , Corachán Lorena , Pallás Vicente , Sánchez-Navarro Jesús Ángel 
Published: September 2023

AbstractAn isolate of chili pepper mild mottle virus (CPMMV-Sp; GenBank OQ920979) with a 99% identity to CPMMV (GenBank MN164455.1) was found in symptomatic pepper plants in Spain. RACE analysis, performed using a stem-loop primer developed in this study to prime at the end of the introduced poly(A)/(U) tail, revealed the presence of an extra 22 nt at the 5' end, starting with a cytosine, which were essential to generate infectious clones. However, the 5' terminal cytosine was dispensable for initiating the infection. The design of two specific digoxigenin riboprobes targeting the more divergent area of CPMMV-Sp, compared to the closely related bell pepper mottle virus (BPeMV) (identity percentage of 80.6% and 75.8%, respectively), showed that both probes specifically detected CPMMV-Sp when the hybridization was performed at 68ºC and 60ºC, respectively. However, the BPeMV probe, targeting a region with an 89.4% identity percentage to CPMMV-Sp, showed cross-hybridization at 60ºC but not at 68ºC. The comparison of the detection limits between molecular hybridization and RT-PCR techniques revealed that the former was 125 times less sensitive than RT-PCR. The analysis of the vertical transmission of CPMMV-Sp using seeds from naturally or mechanically infected pepper plants revealed a transmission percentage ranging from 0.9% to 8.5%. Finally, the analysis of the resistance of capsicum species carrying different alleles of the L gene (L1, L2, L3, and L4) revealed that varieties with the L1 gene were infected by CPMMV-Sp (20–40% of inoculated plants), while varieties with the L2, L3, and L4 genes were resistant.
Improving access to emergency medical services using advanced air mobility vehicles
Authors: Espejo-Díaz Julián Alberto , Alfonso-Lizarazo Edgar , Montoya-Torres Jairo R. 
Published: September 2023

AbstractThe latest advancements in electric vertical take-off and landing (eVTOL) vehicles indicate that soon this technology will be available in multiple fields. One potential application of this new technology is in emergency medical services. These vehicles will be able to reach emergency sites faster than ground ambulances at lower costs than traditional helicopters. So in the following years, eVTOL vehicles could be used for aeromedical transportation. One crucial decision in implementing such a technology in emergency medical services is the location of their take-off and landing areas (vertiports). In this work, we propose a methodology for locating the vertiports in a healthcare network to improve emergency medical services coverage in hard-to-reach zones. We studied the system performance locating the vertiports for emergency services in existing healthcare facilities or outside them as auxiliary bases. In addition, we evaluated the performance of different operational scenarios regarding the use of emergency eVTOL. To do so, we used data analytics techniques (i.e., clustering algorithms) in conjunction with facility location models. The approach is tested using data from the Auvergne-Rhône-Alpes region in France. Results showed that locating the vertiports in existing healthcare facilities is the best choice in terms of coverage of hard-to-reach zones. However, on average, the response times increased compared to locating the vertiports as auxiliary bases outside the healthcare facilities. Besides, the results indicated that implementing eVTOL vehicles for aeromedical transportation can provide better access to emergency medical services in hard-to-reach zones. Still, the autonomy of such vehicles plays an essential role in their applicability.
Examining the Relation Between First-year University Students’ Intention to Drop-out and Academic Engagement: The Role of Motivation, Subjective Well-being and Retrospective Judgements of School Experience
Authors: Passeggia Raffaella , Testa Italo , Esposito Giovanna , Picione Raffaele De Luca , Ragozini Giancarlo , Freda Maria Francesca 
Published: September 2023

AbstractThis study examined the relationships between first-year university students’ academic motivation, retrospective evaluation of school experiences, subjective well-being, engagement and intention to drop out. Self-determination theory, the SInAPSi model of academic engagement, the hedonic approach, and the retrospective judgment process were used to frame the study. A final sample of 565 first-year Italian students enrolled in Science-Technology-Engineering-Mathematics (STEM) courses (Biology, Biotechnologies, Chemistry, Computer Science, Physics, Mathematics) was included. Three mediation models based on structural equations were tested to analyse the relationships between the proposed variables: motivation as an antecedent of dropout intention with only commitment as a mediator (model 1); model 1 + subjective well-being as a second mediator (model 2); model 2 + retrospective judgement as an antecedent (model 3). The results showed that in all models the more autonomous motivational styles predicted students’ engagement, which in turn directly and indirectly influenced their intention to drop out. In model 2, subjective well-being acted as a mediator of the relationships between motivation, engagement and dropout intentions. In model 3, we found that subjective well-being also fully mediated the relationships between retrospective judgement and engagement. Overall, our findings provide new insights into the mechanisms underlying student engagement and dropout at university and may inform university policy.
Mental measurement and the introspective privilege
Authors: Pauen Michael 
Published: September 2023

AbstractAccording to a long-standing belief, introspection provides privileged access to the mind, while objective methods, which we denote as “extrospection”, suffer from basic epistemic deficits. Here we will argue that neither an introspective privilege exists nor does extrospection suffer from such deficits.We will focus on two entailments of an introspective privilege: first, such a privilege would require that introspective evidence prevails in cases of conflict with extrospective information. However, we will show that this is not the case: extrospective claims can prevail in cases of conflict. These conflicts are resolved by an inference to the explanation that best accounts for the available evidence. This explanation may speak in favor of extrospection.Second, given an introspective privilege, the development of extrospective measurement techniques should be restricted by the accuracy of introspective reports. We will argue that this problem is part of a more general issue that comes up with the establishment of measurement in the natural sciences. We will identify three strategies that have proven successful in dealing with the problem in the natural sciences. It will turn out that all these strategies are available for extrospective measurement as well. Consequently, the insufficiencies of introspective reports do not impose a limit on the accuracy of extrospective measurement methods.We conclude that neither an introspective privilege nor basic extrospective deficits exist. This does not mean that extrospection will ever replace introspection. Rather, both approaches provide independent and indispensable forms of epistemic access to the mind.
Importance of Aquitard Response Time for Groundwater Management in Multi-Aquifer Systems Subject to Land Subsidence
Authors: Díaz-Nigenda Juan José , Morales-Casique Eric , Carrillo-García Mauricio , Vázquez-Peña Mario Alberto , Escolero-Fuentes Oscar 
Published: September 2023

AbstractGroundwater management models have been widely applied to obtain optimal pumping strategies for land subsidence control, but most of them do not explicitly incorporate land subsidence variables (such as cumulative settlement and land subsidence rates) within the model constraints and neglect the transient effect due to aquitard storage. Here, three operating scenarios of a hypothetical multi-aquifer system, which include a highly compressible aquitard, were implemented with the aim of evaluating land subsidence and identifying management schemes with the support of an optimization model for groundwater management. In a 50-year management period, maximizing pumping while restricting drawdown to 10 m after year 25 stabilizes groundwater levels within the aquifer, but land subsidence continues to reach 4.8 m at year 50. The effect of reducing pumping rates and how early in the management period this is implemented is also analyzed. Restricting the pumping rate as early as year 6 leads to reduced land subsidence at year 50 by 17%. If pumping reduction is delayed, larger land subsidence rates occurred in the system (7.9, 8.3 and 9.6 cm/year in the tested cases); however, if the total settlement is evaluated as a proportion of the thickness of the aquitard, values of the order of 10% are presented. Our results highlight the importance of timely decisions for groundwater management based on the response time of the aquitards in multi-aquifer systems.
Low-cost materials for swine wastewater treatment using adsorption and Fenton’s process
Authors: Domingues Eva , Lincho João , Fernandes Maria J. , Gomes João , Martins Rui C. 
Published: September 2023

AbstractUntreated swine wastewater (SW) discharge leads to serious consequences such as water quality decreasing related to eutrophication and proliferation of harmful algae containing cyanotoxins, which can cause acute intoxication in humans. The use of untreated pig farming effluent as fertilizer can lead to the accumulation of polluting compounds. Biological treatments can degrade organic matter but have the disadvantage of requiring large areas and high retention times and demonstrating low efficiencies in the degradation of refractory compounds such as pharmaceutical compounds. In this ambit, the performance of four low-cost materials was evaluated for treatment of a swine wastewater using physical–chemical processes such as adsorption and Fenton’s process. The tested materials are two natural resources, red volcanic rock from Canary (RVR) Islands and black volcanic rock (BVR) from Azores, and two industry residues, red mud (RM) and iron filings (IF). Among the tested materials, only IFs are catalytically active for Fenton’s peroxidation. Still, RVR, BVR, and RM were efficient adsorbents removing up to 67% of COD. The combination between adsorption followed by Fenton’s process using IF as catalyst showed interesting results. When RM is applied as adsorbent in the diluted effluent, it was able to remove 67% and 90% of COD for adsorption and adsorption followed by IF Fenton, respectively. At those conditions, the resultant treated effluent accomplishes the requirements for direct discharge in the natural water courses as well as the parameters for water reusing.
Curcumin-Laden Crosslinked Chitosan–PVA Films: The Synergistic Impact of Genipin and Curcumin on Accelerating Wound Closure
Authors: Ramdani Reteesha , Rao Anusha M. , Pokharel Mishal , Mateti Tarun , Likhith K. , Kumari Malti , Bhatt S. Supriya , Nune Manasa , Thakur Goutam 
Published: September 2023

AbstractWound dressings play a critical role in healing by maintaining a moist environment and protecting against infection. Here, we fabricate crosslinked films of chitosan–polyvinyl alcohol–genipin–curcumin to investigate the synergistic wound-healing effect of genipin and curcumin. The chemical bonding, morphology, strength, water retention capacity, curcumin release characteristics, and cytotoxicity of the films were investigated. The results showed a 192% increase in tensile strength and good water retention, and the infrared analysis and scanning electron microscopy micrographs confirmed genipin crosslinking and the presence of curcumin in the films, whose morphology was uniform and continuous. The curcumin-loaded films were found to have insignificant cytotoxicity against 3T3 fibroblast cells, proving their biocompatibility. The curcumin dissolution tests determined the amount of curcumin released from the films with time, and assessed the release characteristics to be sustained at all pH levels. In vivo trials were carried out on rodents to evaluate the wound-healing effects of the films, and the results showed that the curcumin-incorporated crosslinked films accelerated wound healing compared to the uncrosslinked and curcumin-absent films, confirming their effectiveness for wound healing.