bluuebunny/crossref_metadata_2025_split huggingface dataset:
Premenstrual Syndrome, Life Style &amp; Behavioral Coping Mechanisms and Associated Factors Among Public High School Regular Female Students at Bahir Dar City, Northwest, Ethiopia
Authors: Zeleke Balew , Workineh Yinager , Melese Addisu , Semachew Ayele , W/giorgis Teshager , Yigizaw Molla 
Published: January 2023

Abstract
Objective: The objective of this study was to assess premenstrual syndrome, life style & behavioral coping mechanisms and associated factors among public high school regular female students at Bahir Dar city, Northwest, Ethiopia,2020
Result: Out of 422 study participants,408 respondents participated in the study making the response rate 96.7%. In the current study ,the prevalence of premenstrual syndrome was 41.2% (95% CI:36.3,45.8).
Family history of premenstrual syndrome (AOR:4.18,95% CI:[2.61,6.71]) and using hormonal contraceptives (AOR:10.30 CI:[4.39,24.17]) were positively associated factors with premenstrual syndrome.On the other hand , history of sexual intercourse (AOR:0.18,95% CI:[0.08,0.43]) was negatively associated with premenstrual syndrome.Visiting clinics 174 (42.6%), listening music 163 (40.0%) and taking shower 155(38.0%) were the most frequently practiced life style & behavioral coping mechanisms for premenstrual symptoms by the respondents.
The current study concluded that premenstrual syndrome was high among the study participants.Therfore,this study recommended that health care workers should work on awareness creation about premenstrual syndrome and life style & behavioral coping mechanisms and further large scale researches need to done.
Online leakage detection system based on EWMA-enhanced Tukey method for water distribution systems
Authors: Wan Xi , Farmani Raziyeh , Keedwell Edward 
Published: January 2023

Abstract
Real-time leakage detection based on pressure and flow data has become increasingly essential for water distribution systems (WDSs). Recent data-driven leakage detection approaches have largely focused on burst detection characterised as sudden outflow or sudden pressure drops but did not mention the ability to detect gradual leakage events that do not have sudden change and could cause more water loss. This study proposes an online leakage detection system based on the exponential weighted moving average (EWMA)-enhanced Tukey method to help monitor gradual leakage events of WDSs. The proposed online system comprises three main parts: data pre-processing, the online detection sub-system, and the parameter updating sub-system. The proposed online system is based on lightweight and powerful statistical tools without complex model construction. The effectiveness of the proposed system is demonstrated on leakage datasets under various real-world scenarios, including gradual leakages and bursts. The results showed that the proposed EWMA-enhanced Tukey method could detect gradual leakage events quickly while generating low false alarms. The proposed method is computationally effective and able to deal with non-stationary behaviours automatically.
Analysis of the climate change impact on the spatiotemporal drought in the Gaza region of the southeastern Mediterranean
Authors: Eljamassi Alaeddinne , Al-Najjar Hassan , Abdel latif Mahmoud , Dweikat Ashraf , Aljamal Maher 
Published: January 2023

Abstract
The southeast Mediterranean region of the Gaza Strip is showing traces of evolving drought patterns driven by the impacts of climate change. The analysis of rainfall data at eight meteorological stations for a period extending over 48 years from 1974 to 2021 shows obvious variations in the spatiotemporal distribution of the rainfall over the Gaza Strip. The total monthly rainfall trend analysis for the wet months indicates a decreasing trend during February, March, April, and November with a ratio ranging between −16 and −62% and an increasing trend of about 35 and 141% through October at each of the meteorological stations. However, January shows an increasing trend of about 1–27% at all meteorological stations except Nussirat where a decline of about −7% is recorded while December refers to an increasing trend of about 5–27% in the north area of Gaza and declining trend of −2 to −17% over the southern region of the Gaza Strip. The drought analysis using the SPI indicator refers to a significant development of drought during the years 1990, 1999, 2010, and 2014 in the Gaza Strip with a major incident of occurrence where specifically, the monthly drought in terms of SPI-1 is identified as moderate and mild by about 15–21 and 27–56%, respectively. The agricultural drought of SPI-3 is nominated by severe, moderate, and mild severity with an incident reaching 11%, 8–11%, and 21–52%, respectively. However, the hydrological droughts demonstrated by the 9-month SPI-9 and 12-month SPI-12 potentially occur in extreme, severe, moderate, and mild with a probability of incident defined by up to 4, 13, 15, and 28–40%, respectively, for SPI-9 and by up to 4, 6, 11 and 38% extreme, severe, moderate, and mild, respectively, in case of SPI-12.
Sustainable planning of multipurpose hydropower reservoirs with environmental impacts in a simulation–optimization framework
Authors: Hatamkhani Amir , Moridi Ali , Randhir Timothy O. 
Published: January 2023

Abstract
Hydropower projects involve enormous investments that require an efficient cost–benefit framework and optimization model for proper development. Dams and hydropower plants have many impacts on the environment. These environmental impacts are often not included in the economic calculations and planning of the projects, which leads to the loss of natural resources. The primary purpose of this research is to incorporate environmental impacts into optimization and decision-making. A comprehensive simulation–optimization model is developed to optimize hydropower decisions. The positive and negative values of environmental impacts are incorporated into an economic objective function under different scenarios, and optimal design was done for each scenario. The results show that considering environmental economics affects the multipurpose hydropower project's NPV and decision outcomes. Considering environmental impacts compared to not considering them has reduced NPV of the project by 13.9%. The results emphasize the importance of including these impacts to achieve sustainable development and management.
Evaluation of water safety plan implementation at provincial water utilities in Vietnam
Authors: Nguyen Viet-Anh , Tran Thi Hien Hoa , Nijhawan Anisha , Howard Guy , Nghia Ton Tuan 
Published: January 2023

Abstract
This study evaluated the experience of implementing water safety plans (WSPs) in Vietnam. WSPs were introduced in Vietnam by the World Health Organization (WHO) in collaboration with the Ministry of Construction in 2006 and have been a mandatory requirement for municipal water supplies since 2012. Using a mixed-methods approach, we collected data on the perceived benefits and challenges of WSP implementation from 23 provincial water companies between August and November 2021. Potential public health benefits of improved water quality were a key motivation; 87% of the water utilities were also motivated by the risk of climate change and prepared response plans to climate-related extreme events as part of WSPs. A decrease in E. coli and an improvement in disinfectant residual in treated water were reported by 61 and 83% of the water supplies, respectively. Sixty-five percent of the water supplies also reported improved revenue and cost recovery. Key barriers to WSP implementation were a lack of WSP guidance suitable for the local context (87%) and insufficient funds for WSP implementation (43%). Our study highlights the need for improved support and capacity building along with locally suited guidance on WSP implementation and audit.
Perfusion Deficits in Different Mechanisms of Two Subtypes of Acute
Stroke with Diffusion MRI Confirmation
Authors: Hu Wenli , Zhu Cuiting , Qin Wei 
Published: January 2023

Background:
Branch atheromatous disease (BAD) and lacunar infract (LI) are the different
mechanisms of subtypes of acute stroke. We aimed to investigate perfusion deficits and clinical
characteristics of the different mechanisms of two subtypes of acute stroke.

Materials and Methods:
Five hundred and ninety-nine CTP examinations were retrospectively reviewed
between January and December 2021 in patients with acute stroke symptoms with CTP
within 12 hours and MRI within 7 days of symptom onset. Based on diffusion MRI, the patients
were assigned to one of two subtypes: BAD and LI. Lesion volumes were measured on NCCT,
CTA, CBV, CBF, MTT, and TTP maps by region-of-interest analysis and were confirmed by follow-
up MRI.

Results:
One hundred thirty-three patients met the inclusion criteria (26.3% female). The BAD
group was present in 104 of 133 (78.2%), and the LI group 29 of 133 (21.8%). Based on CT perfusion,
42 of 78 (53.8%) BAD group and 5 of 18 (27.8%) LI group had perfusion deficits in the supratentorial
region. BAD had a higher proportion of abnormal perfusion than LI patients, with a
significant difference (P < 0.05). The sensitivity of CTP ranged from 21.4% (CBV) to 90.5% (TTP);
specificity ranged from 97.2% (TTP) to 100% (CBV, CBF, and MTT) in BAD patients.

Conclusion:
CTP has high specificity in identifying BAD. Compromised perfusion deficits are
more presented in BAD patients compared with LI. CT perfusion imaging may be useful for determining
the clinical significance of perfusion abnormalities in BAD occurrence.
Efficacy of N-acetylcysteine as Add-on Therapy for the Management of
Chronic Pelvic Pain Syndrome in Women
Authors: Mohseni Maede , Rahimi Somayeh , Mirjalili Mahtabalsadat , Mohammadi Younes , Mehrpooya Maryam 
Published: January 2023

Purpose:
Considering supportive evidence on N-acetylcysteine (NAC) effectiveness in
neuropathic pain syndromes, we conducted this study to evaluate its effect on women suffering from
chronic pelvic pain syndrome (CPPS).

Methods:
In a randomized, double-blind study, 106 women with CPPS were assigned to receive
NAC+amitriptyline or placebo+amitriptyline treatment. Amitriptyline was administrated at a dose of
25 mg/daily and NAC and placebo at 600 mg twice daily. The effect of treatment was assessed on the
National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) and its domain scores,
including pain, urinary symptoms, and quality of life impact scores at weeks 4 and 8 after treatment.
The global response was also assessed on the 7-point patient-reported Global Response Assessment
(GRA) scale at the end of the study.

Results:
By week 4, comparative improvements were noticed in the two groups' NIH-CPSI total score
and domain scores. From week 4 to week 8, we noted the superior efficacy of NAC+amitriptyline
treatment over placebo+amitriptyline in improving the NIH-CPSI total score and its domain scores, as
the proportion of patients responding to treatment (the subjects with ≥ 6-point reduction in the total
NIH-CPSI score), as well those reporting marked or moderate improvements in their overall symptoms
on GRA was significantly more significant in patients receiving NAC+amitriptyline treatment
relative to those receiving placebo+amitriptyline treatment.

Conclusion:
These findings provided preliminary evidence regarding the possible role of NAC as an
adjunct therapy in the management of CPPS in women, which needs to be validated in future studies.
Does Diffusion Restriction Pattern on MRI Predict Stroke Etiology in a
Cancer Patient?
Authors: Asil Talip , Kolukisa Mehmet , Koyuncu Bahar Aksay , Bayrakoglu Alişan 
Published: January 2023

Background:
Stroke and cancer are two of the most common health problems. Moreover,
stroke is more common in patients with cancer than in the normal population, due to coagulation problems.
Knowing the etiology of stroke is important for determining treatment options. This study aimed
to determine the relationship between ischemic lesion topographies using diffusion-weighted magnetic
resonance imaging (MRI) and the etiology of stroke in patients with cancer.

Patients and Methods:
All patients with ischemic stroke in the Bezmialem Stroke Registry over a 4-
year period were retrospectively analyzed in this study. Patients with acute ischemic stroke and additional
diagnoses of solid and active malignancy (excluding hematologic malignancies) were included
in the analysis. We investigated whether there was a relationship between the etiology of patients with
cancer-related stroke according to the stroke etiologic classification and the diffusion restriction patterns
on MRI.

Results:
In this registry, 32 of 1472 patients were diagnosed as having active cancer. Fourteen patients
were evaluated as having definite cardioembolism, eight patients as probable cardioembolism, and four
patients had inadequate examinations. Only one patient was classified as having an atherothrombotic
stroke. Isolated acute infarction was seen in 15 of 32 patients. In patients with multiple acute infarct
areas (n=17), acute lesions characterized by micro embolisms in a single vessel area were detected in
four patients, and acute lesions characterized by bilateral (anterior and/or posterior system) micro embolisms
in more than one vessel area in 13 patients.

Conclusion:
The most common etiology of stroke in patients with cancer was found to be embolic/
cardioembolic. This is important for the treatment plans for ischemic stroke in patients with cancer.
Revisiting the South Indian Traditional Plants against Several Targets of
SARS-CoV-2 - An in silico Approach
Authors: Jupudi Srikanth , Rajala Srikala , Gaddam Narasimha Rao , Swaminathan Gomathi , Peesa Jaya Preethi , Rajagopal Kalirajan , Azam Mohammed Afzal 
Published: January 2023

Background:
The south Indian Telugu states will celebrate a new year called ‘Ugadi’ which is a south Indian traditional festival. The ingredients used in ugadi pachadi have often also been used in food as well as traditional Ayurveda and Siddha medicinal preparations. Coronaviruses (CoVs) are a diverse family of enveloped positive-sense single-stranded RNA viruses which can infect humans and have the potential to cause large-scale outbreaks.

Objective:
Considering the benefits of ugadi pachadi, we investigated the binding modes of various phytochemical constituents reported from its ingredients against five targets of SARS-CoV-2.

Methods:
Flexible-ligand docking simulations were achieved through AutoDock version 1.5.6. Following 50ns of molecular dynamics simulation using GROMACS 2018.1 software and binding free energy (ΔGbind) of the protein-ligand complexes were calculated using the g_mmpbsa tool. ADME prediction was done using Qikprop of Schrodinger.

Results:
From the molecular docking and MM/PBSA results compound Eriodictin exhibited the
highest binding energy when complexed with nucleocapsid N protein (6M3M) (-6.8 kcal/mol, -
82.46 kJ/mol), bound SARS-CoV-2-hACE2 complex (6M0J) (-7.4 kcal/mol, -71.10 kJ/mol) and
Mpro (6XR3) (-8.6 kcal/mol, -140.21 kJ/mol). Van der Waal and electrostatic energy terms highly
favored total free energy binding.

Conclusion:
The compounds Eriodictin, Vitexin, Cycloart-3, 24, 27-triol, Agigenin, Mangiferin,
Mangiferolic acid, Schaftoside, 27-Hydroxymangiferonic acid, Quercetin, Azadirachtol, Cubebin,
Isomangiferin, Isoquercitrin, Malicarpin, Orientin and procyanidin dimer exhibited satisfactory
binding energy values when compared with standard molecules. The further iterative optimization
of high-ranked compounds following validation by in vitro and in vivo techniques assists in discovering
therapeutic anti-SARS-CoV-2 molecules.
Graphene Used for Energy Conversion and Storage by Electrochemistry:
A Brief Global Overview
Authors: Liu Miao , Dai Yexin , Maryam Bushra , Cui Jinran , Liu Xianhua 
Published: January 2023

Background:
Graphene and its derivatives have been widely used in modern electrochemical-
related technologies due to their versatile structure, tunable conductivity, and large
specific surface area. However, there is a need to provide the latest global literature overview in
this field.

Methods:
In this study, we reported a literature overview of current developments in the applications
of graphene in energy conversion and storage by electrochemistry. In this overview, 1285
pieces of literature were retrieved and analyzed based on the web of science core database using
bibliometric tools.

Results:
The major contributing countries are China and the United States. The most widespread
fields are the development of novel nanomaterials and catalysts and approaches to improve the
electrocatalytic performance of batteries and supercapacitors. The hotspots of current research
include sodium-ion batteries, lithium-sulfur batteries, sulfur-doped electrodes, and the study of
high-efficiency electrocatalysts for oxygen and evolution reactions.

Conclusion:
With the continuous development in this field, scientists are committed to continuously
improving the performance of energy equipment. The applications of graphene-based
materials for electrochemical energy conversion and storage are briefly summarized. The challenges
and prospects for future research in this field are also discussed.
Capturing the Dynamics of the Social Environment Through Experience Sampling Methods, Passive Sensing, and Egocentric Networks: Scoping Review
Authors: Langener Anna M , Stulp Gert , Kas Martien J , Bringmann Laura F 
Published: January 2023

Background
Social interactions are important for well-being, and therefore, researchers are increasingly attempting to capture people’s social environment. Many different disciplines have developed tools to measure the social environment, which can be highly variable over time. The experience sampling method (ESM) is often used in psychology to study the dynamics within a person and the social environment. In addition, passive sensing is often used to capture social behavior via sensors from smartphones or other wearable devices. Furthermore, sociologists use egocentric networks to track how social relationships are changing. Each of these methods is likely to tap into different but important parts of people’s social environment. Thus far, the development and implementation of these methods have occurred mostly separately from each other.

Objective
Our aim was to synthesize the literature on how these methods are currently used to capture the changing social environment in relation to well-being and assess how to best combine these methods to study well-being.

Methods
We conducted a scoping review according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines.

Results
We included 275 studies. In total, 3 important points follow from our review. First, each method captures a different but important part of the social environment at a different temporal resolution. Second, measures are rarely validated (>70% of ESM studies and 50% of passive sensing studies were not validated), which undermines the robustness of the conclusions drawn. Third, a combination of methods is currently lacking (only 15/275, 5.5% of the studies combined ESM and passive sensing, and no studies combined all 3 methods) but is essential in understanding well-being.

Conclusions
We highlight that the practice of using poorly validated measures hampers progress in understanding the relationship between the changing social environment and well-being. We conclude that different methods should be combined more often to reduce the participants’ burden and form a holistic perspective on the social environment.
Pengaruh Komponen 4A terhadap Minat Berkunjung Kembali dengan Kepuasan sebagai Variabel Intervening pada Telaga Biru Cisoka, Kabupaten Tangerang, Provinsi Banten
Authors: Nurbaeti Nurbaeti , Rahmanita Myrza , Amrullah Amrullah , Ratnaningtyas Heny , Nurmalinda Elda 
Published: January 2023

Penelitian ini bertujuan untuk mengetahui pengaruh atraksi, aksesbilitas, amenitas dan ancillary terhadap minat berkunjung kembali dengan kepuasan sebagai variabel intervening pada Telaga Biru Cisoka, Kabupaten Tangerang, Provinsi Banten. Metode penelitian ini menggunakan analisis jalur. Populasi dalam penelitian ini adalah kaum milenial yang mengunjungi Telaga Biru Cisoka, sedangkan sampel berjumlah 150 responden. Teknik pengambilan sampel menggunakan purposive sampling. Hasil penelitian menunjukkan secara parsial hanya ancillary yang tidak berpengaruh signifikan terhadap kepuasan kaum milenial dan minat berkunjung kembali kaum milenial. Kemudian secara parsial secara parsial hanya ancillary tidak berpengaruh signifikan terhadap minat berkunjung kembali kaum milenial melalui kepuasan kaum milenial. Telaga Biru Cisoka memberikan kepuasan dan minat kunjung kembali karena: (1) adanya atraksi alam berupa keindahan warna telaga dan atraksi buatannya meliputi wisata selfie, ayunan, jungkat-jungkit, flying fox, wahana bebek, penyewaan perahu; (2) karena adanya aksebilitas yang baik dan mudah dijangkau seperti kondisi jalan berbeton dan beraspal, jarak tempuh yang singkat, transportasi yang memadai; (3) adanya amenitas yang cukup meliputi area parkir cukup luas, air bersih yang sudah ada, warung makan. Untuk Pengelola Objek Wisata disarankan menambah atraksi baru, melengkapi dan mengelola serta merawat fasilitas.
The Function and Meaning of Tope’ le’leng in the Death Ritual of The Kajang Tribe, South Sulawesi
Authors: Juniati Ninik 
Published: January 2023

Tope’ le’leng in the Kajang language means black sarong and is a typical sarong of the Kajang tribe worn by men and women, both for daily wear and worn at various ceremonies held by this tribe. The study of tope’ le’leng has been quite a lot. Still, no one has discussed its function and meaning in the death ritual of the Kajang tribe, considering that tope’ le’leng has been recognized as one of the Kajang tribe’s identities among other tribes in Indonesia. This study examines the function and meaning of Tope’ le’leng in death rituals, starting from when the corpse was still at home, funeral preparation, funeral processions, and follow-up rituals until 100 days. This research used an ethnographic approach with descriptive analysis. Data analysis used triple pattern (Pola Tiga) theories in Paradoxical Aesthetics from Jakob Sumardjo. The data sources in this study are Tope’ le’leng, the funeral ritual itself, the shaman who led the death rituals, and the local community who followed the funeral ritual. Data collection techniques used participatory observation and interviews. The results showed that Tope’ le’leng functioned as an object of donation, a sign of grief. It is a marker of a family of mourning (not wearing clothes other than tope’ le’leng) as a ritual object to cover the bamboo coffin and Pammorangan. Tope’ le’leng, as a ritual object, shows the social strata or economic level of the grieving family in the community. The Kajang people believed that the deceased spirit could see the family and the shaman as long as they did not wear clothes other than tope’ le’leng for 100 days. As one of the ritual and sacred objects, tope’ le’leng has presented a moment of transcendence and belief in the existence of spirits in death rituals. Based on the triple pattern theory (Pola Tiga), namely the relationship between the upper, middle, and lower worlds. Tope’ le’leng has another function as a relationship connector between God, man, and nature. The simplicity of its form and composition does not detract from its function and meaning and even reinforces its sacredness as a ritual object in patuntung beliefs.