bluuebunny/crossref_metadata_2025_split huggingface dataset:
Correlation between epicardial adipose tissue and atrial fibrillation burden in coronary artery bypass graft surgery
Authors: Bolzan Bruna , Morani Giovanni , Rizzati Vanni , Zamboni Mauro , Mazzali Gloria , Franzese Ilaria , Tomasi Luca , Mugnai Giacomo , De Manna Davide , Benfari Giovanni , De Caro Annamaria , Cortinovis Matteo , Faggian Giuseppe , Luciani Giovanni Battista , Ribichini Flavio Luciano 
Published: March 2023

Aims
Recent studies suggest an association between epicardial adipose tissue (EAT) and atrial fibrillation. The aim of the study is to evaluate the quantitative and qualitative characteristics of EAT in relation to atrial fibrillation burden after coronary artery bypass graft (CABG).

Methods
This prospective single-centre study included patients undergoing CABG. The patients underwent transthoracic echocardiography and collection of a bioptic sample containing right appendage and EAT during CABG for histological characterization. After surgery, clinical and telemetry data were collected.

Results
Fifty-six consecutive patients were enrolled. The mean postsurgical hospitalization was 7.9 ± 3.7 days. Twenty-two patients had at least one episode of atrial fibrillation. In the atrial fibrillation group, there was a bigger atrial volume, a higher degree of diastolic disfunction, a thicker layer of EAT and an older median age in comparison with the group that did not develop it. EAT with a cut-off of 4 mm was a predictor of atrial fibrillation with an odds ratio (OR) of 1.49 (confidence interval (CI) 1.09–2.04), 73% of sensibility and 89% of specificity. From the histological analyses, the patients with atrial fibrillation had a significantly higher percentage of fibrosis. At univariate analysis, atrial volume [OR 1.05, CI 1.01–1.09, P = 0.022], E/A rate (OR 0.04, CI 0.02–0.72 P = 0.29), the percentage of fibrosis (OR 1.12, CI 1.00–1.25, P = 0.045) and age (OR 1.17, CI 1.07–1.28, P = 0.001) were predictors of atrial fibrillation. At multivariate analysis, atrial volume (P = 0.027), fibrosis (P = 0.003) and age (P = 0.039) were independent predictors of atrial fibrillation.

Conclusion
Postcardiac surgical atrial fibrillation is frequent. EAT thickness, atrial volume, fibrosis and age are predictors of postcardiac surgical atrial fibrillation.
Acute expansion of nitinol-based self-expandable device in patients undergoing transfemoral aortic valve implantation
Authors: Spaccarotella Carmen A.M. , Sorrentino Sabato , Mongiardo Annalisa , Riverso Vincenzo , Mancuso Cinzia , Giordano Salvatore , Esposito Giovanni , Indolfi Ciro 
Published: March 2023

Background
The acute adaptation of the nitinol-based stent frame self expandable valve to the aortic root after deployment is poorly understood. Accordingly, this study aimed to assess the occurrence, degree and determinants of acute adaptation of the nitinol-based stent frame self-expandable valves after implantation.

Methods
This is a single-site prospective registry including patients undergoing transcatheter aortic valve replacement (TAVR) with a widely used second-generation nitinol-based self-expandable device (Evolut R, Medtronic, Minneapolis, Minnesota, USA). We measured valve diameters at three different sections: distal (aortic) level, central (annulus) level and proximal (ventricular) level. Valve expansion was estimated by the difference between the diameters calculated immediately after valve deployment (A) and at the end of the procedure (B). The absolute and relative stent changes were defined as B-A and (B-A)/B∗100, respectively. A linear regression model was performed to test the association between the degree of valve extension at each segment with baseline and procedural characteristics.

Results
A total of 58 consecutive TAVR patients were included in this analysis, with a mean age of 82.12 ± 5.28 years. Out of the total, 46% of the patients had chronic kidney disease, 32% had diabetes and 76% had dyslipidaemia. The mean procedural time was 28.11 ± 11.6 min, with 53.45% of predilation. Postdilation was performed only in 3.5% of patients. Final stent diameters were significantly higher than those achieved immediately after valve implantation – an observation that was consistent for all the segments: 0.50 ± 0.51 mm and 2.48 ± 2.57% (P < 0.01) in the proximal, 0.46 ± 0.57 mm and 2.39 ± 2.96% (P < 0.01) in the central, as well as 0.58 ± 0.59 mm and 2.14 ± 2.14% (P < 0.01) at the distal segments. Postdilation significantly affected the expansion of the central segment, and, albeit not significantly, the proximal one, while no changes were observed for the distal portion of the platform.

Conclusion
This is the first study to have documented a significant degree of the Evolut R self-expandable valve expansion after deployment. However, further studies are required to assess the short- and long-term time course of self-expandable valve enlargement and the clinical relevance of this finding.
Comparison of caregivers’ assessments of clinical outcome in dogs with idiopathic epilepsy administered levetiracetam, zonisamide, or phenobarbital monotherapy
Authors: Gristina Bryanna R. , Waldron Rennie J. , Nettifee Julie A. , Muñana Karen R. 
Published: March 2023

Abstract

OBJECTIVE
To investigate caregivers’ assessments of outcome in dogs with idiopathic epilepsy (IE) administered levetiracetam (LEV), zonisamide (ZNS), or phenobarbital (PB) monotherapy.

ANIMALS
100 dogs with IE administered LEV (n = 34), ZNS (31), or PB (35) monotherapy between January 1, 2003, and February 6, 2019, and survey responses from their caregivers.

PROCEDURES
Information on duration of therapy, adverse effects (AEs), and outcome was obtained from medical record review and caregiver questionnaire.

RESULTS
A significant improvement in mean quality of life score was reported during monotherapy (7.7; SD, 2.14) compared to before treatment (6.25; SD, 2.63; P < .0001), with no difference identified between monotherapy groups. Compared to ZNS monotherapy, dogs prescribed PB monotherapy had a significantly younger median age at seizure onset (2.6 vs 4.3 years; P = .024). A significant relationship was identified between the occurrence of reported AEs and monotherapy group, with a higher prevalence in the PB group (77% [27/35]) and a lower prevalence in the ZNS group (39% [12/31]; P = .0066). Treatment failure rates for PB, LEV, and ZNS monotherapy were 51%, 35%, and 45%, respectively, with failure attributed most commonly to inadequate seizure control. No significant difference was identified between groups with respect to rate of or time to failure.

CLINICAL RELEVANCE
Most caregivers reported a favorable outcome with administration of LEV, ZNS, or PB monotherapy to dogs with IE. Phenobarbital is associated with the highest prevalence of AEs but no difference in quality of life score. Prospective controlled studies are needed to further compare the efficacy and safety of these monotherapies in dogs with IE.
The High Penetrability of Nanoparticles into Bacterial Membranes: A Key of a Potential Application
Authors: Meliani Amina , Khelil Fatima Zohra Amel , Nair Samira 
Published: March 2023

Abstract
Currently, nanoparticles have gained considerable attention for the treatment of bacterial infectious diseases. The possibility for using this technology as an alternative therapeutic strategy for controlling microbial biofilms, colonizations and infections has been the subject of intense investigations. Even though, the potential toxicity and disadvantage of using nanoparticles, researchers focused on their high penetrability into bacterial membranes, capabilities to disrupt biofilm formation and the role of chemotaxis in this interaction. Face to this significant debate, we discuss the link between metal resistance, bacterial chemotaxis and the promising use of nanoparticles (NP). P. aeruginosa has emerged as a model organism for biofilm studies, the aim of this review is to provide a concise and comprehensive survey of certain relevant aspects related to the research on nanoparticles and these bacteria.
Bacterial Interactions Affecting Chemotherapy Effectiveness
Authors: Chambers Jenni , Illingworth Thomas Arron 
Published: March 2023

Chemotherapy resistance is a recurring challenge in cancer treatment, with specific bacteria impairing the effectiveness of certain chemotherapies. This study reviews three bacteria and their impact on chemotherapy drugs: Mycoplasma and gemcitabine, Fusobacterium nucleatum and oxaliplatin, bacterial β-glucuronase and irinotecan. Bacteria can have wide-ranging effects on cancer treatment; for instance, they may affect drug metabolism, alter toxin conversion, and encourage cancer growth. Whilst the presence of these bacteria was found to have a detrimental effect on the efficacy of chemotherapy treatment, we also consider wider interactions and interdependencies of the microbiota with drug treatments. Some cancer therapies depend on the delicate balance of the microbiome whilst simultaneously disrupting it by their very nature, particularly when antibiotics are introduced. Further research into the complex relationship between bacteria and the tumour micro-environment is needed. Treatments that focus on the immune-oncology microbiome axis or that explore genetic predisposition through the use of biomarkers could also support a more personalised approach.
Penerapan Sistem Informasi Akuntansi Pembayaran Izin Tinggal Warga Negara Asing Pada Kantor Imigrasi Kelas Iii Non TPI Banggai
Authors: Moridu Irwan , Fitriani Fitriani 
Published: March 2023

The purpose of this-study was to determine and assess the Accounting Information System for Foreigners' Stay Permit Payments at the Immigration Class III Non TPI Banggai Office in Central Sulawesi. Data collection techniques used are by conducting documentation, interviews, and observations. The analysis used in this study is a descriptive method that is by analyzing the Accounting Information System for Foreigners' Residence Permit Payment conducted at the Immigration Class III Non TPI Banggai Office. The results of this study are in the Information System for Foreigners 'Permit Payments Accounting which is a computerized process and the foreigners' permit stay payment system uses a symphony payment system or online PNBP Information System that is managed directly by the Directorate General of Budget so that the results of the stay permit payment transaction carried out by the guarantor at the office the post or bank can directly enter can directly enter the state treasury as non-tax state revenue (PNBP), in general the Accounting Information System for Paying Foreign Residents Permits at the Immigration Class III Non TPI Banggai Office in Central Sulawesi is quite good and adequate.
Keywords: System, Payment, Residence Permit
Pengaruh Ukuran Perusahaan, Kualitas, Dan Independensi Komite Audit Terhadap Kecurangan Pelaporan Keuangan Pada Perusahaan BEI
Authors: Fitriyani Fitriyani , Noviyanti Suzy 
Published: March 2023

Penelitian ini menguji pengaruh ukuran perusahaan, kualitas, dan independensi komite audit terhadap kecurangan pelaporan keuangan pada perusahaan BEI. Populasi yang dipakai pada penelitian ini adalah perusahaan yang terdaftar di BEI pada tahun 2014 sampai dengan tahun 2018. Berdasarkan data dan kriteria yang tersedia, diperoleh sampel sebanyak 100 perusahaan dimana 60% merupakan perusahaan non fraud dan 40% sisanya merupakan perusahaan fraud. Teknik analisis yang dipakai pada penelitian ini adalah metode regresi logistik yaitu dengan membandingkan perusahaan fraud dan perusahaan non fraud. Sebelum pengujian dilakukan, terlebih dahulu dilakukan analisis deskriptif pada data. Hasil penelitian membuktikan bahwa ukuran perusahaan dan independensi komite audit tidak berpengaruh signifikan terhadap kecurangan pelaporan keuangan. Sedangkan kualitas komite audit sangat berpengaruh signifikan terhadap kecurangan pelaporan keuangan. Penelitian ini bisa dijadikan sebagai bahan pertimbangan untuk investor apakah mereka ingin menanamkan modalnya di perusahaan yang akan dipilihnya nanti. Selain itu penelitian ini juga bermanfaat bagi para manajer, pemegang saham, dan pembuat kebijakan pada suatu perusahaan untuk dapat menyempurnakan sistem tata kelola perusahaan.
Kata Kunci : kecurangan pelaporan keuangan, komite audit, kualitas.
Pengaruh Likuiditas Terhadap Kinerja Perusahaan Pada Perusahaan-Perusahaan Manufaktur Yang Terdaftar Di Bursa Efek Indonesia (BEI) Periode 2017-2019
Authors: Anindita Nurul Rizki , Noegroho Yefta Andi Kus 
Published: March 2023

Object of this research is manufacturing companies are listed on the Indonesia Stock Exchange (IDX) from 2017 to 2019. The data used is secondary data, in the form of annual financing reports of manufacturing companies listed on the Indonesia Stock Exchange (IDX) from 2017 to 2019. The data used in this research are secondary data, in the form of annual financial reports of manufacturing companies listed on the Indonesia Stock Exchange (IDX) from 2017. up to 2019. The purpose of this research is to determine whether the effect of current company liquidity is better in realizing company performance. This research used 194 manufacturing companies listed on the Indonesia Stock Exchange (IDX). The sampling technique was purposive sampling which resulted in a total of 189 companies as the research sample. This analysis uses multiple regression analysis and the significant value of the t-test results of each variable. This research is a quantitative with data processing using Statistical Product and Service Solution (SPSS). The results of this research indicate that the liquidity variable has a significant effect on company performance and company size has an effect as a moderating variable on the relationship between liquidity and company performance.

Keywords: Liquidity, Firm Performance, Firm Size
Analisis Pengaruh Firm Size dan Sales Growth Terhadap Return Saham
Authors: Maramis Anisa , Norisanti Nor , Komariah Kokom 
Published: March 2023

The purpose of this study was to determine the effect of Firm Size and Sales Growth on Stock Return in food and beverage sub-sector companies in 2017-2020. The method used is a quantitative method through an associative descriptive approach. The sample used in this study is by using purposive sampling. Of the 30 members of the food and beverage sub-sector companies, 10 companies were selected as samples. Using secondary data collection techniques and multiple linear regression analysis methods to test this research. The results of this study indicate that there is no influence between firm size on stock returns and there is an influence between sales growth on stock returns in food and beverage sub-sector companies listed on the Indonesia Stock Exchange.

Keywords : Firm Size, Sales Growth, Stock Return
Pengaruh Current Ratio, ROA, Total Assset Turnover Dan Debt To Equity Ratio Terhadap Harga Saham Pada Perusahaan Sektor Industri Dasar Dan Kimia Yang Terdaftar Di BEI
Authors: Sari Riana Permata , Sihombing Mey Tisa , Manurung Ruth Dameria , Aruan Deasy Arisandy 
Published: March 2023

This study aims to determine the effect of the variable current ratio, ROA, total asset turnover and debt to equity ratio on stock prices. The research population obtained 67 companies selected using purposive sampling with certain criteria as many as 27 companies. The type of data used in this research is quantitative data. The data source in this research is secondary data. The data collection technique is done by using documentation technique and data analysis using multiple linear analysis. The results of the research partially show that ROA has a positive and insignificant effect on stock prices, total asset turnover has a negative and significant effect on stock prices, while the current ratio and debt to equity ratio have no significant effect on stock prices. The research results simultaneously show the current ratio, ROA, total asset turnover and debt to equity ratio to stock prices.
Keywords: CurentRaio, Debt To Equity Ratio, ROA, Stock Price, Total Asset Turnover
Pengaruh Motivasi, Pelatihan Dan Komunikasi Terhadap Kinerja Karyawan Pada Perusahaan Daerah Air Minum Tirtanadi Cabang Berastagi
Authors: Gurusinga Susi Br , Novita Herlina , Sinaga Dewi Indriani , Simamora Melda Fitri Yanti , Novaresita Ruth Sania 
Published: March 2023

This research was conducted to determine the influence of motivation, training, and communication on the performance of employees at the Tirtanadi Drinking Water Regional Company Berastagi Branch. This type of research uses descriptive research. The number of research samples as many as 52 employees of Tirtanadi Drinking Water District Company Berastagi Branch. The results showed that partially motivation, training, and communication significantly affect the performance of employees at the Tirtanadi Drinking Water Regional Company Berastagi Branch. Simultaneous test results showed that motivation, training, and communication significantly affected the performance of employees at the Tirtanadi Drinking Water Regional Company Berastagi Branch. The influence of motivation, training, and communication on employee performance at Tirtanadi Drinking Water District Company Berastagi Branch by 70.9%.

Keywords: Training, Training, Communication, Office Employees
Pengaruh Budaya Organisasi, Pelatihan Kerja , Dan Pengembangan Karir Terhadap Kinerja Karyawan Pada PT. Perkasa Internusa Mandiri Medan
Authors: Sinaga Sefriani , Zebua Vetriana , Simanjuntak Demak Claudia Yosephine 
Published: March 2023

This research aims to provide empirical evidence regarding the organizational culture of job training and development career on employee performance at PT. Perkasa Internusa Mandiri Medan in the future by testing each variable. The population in this study were 110 employees and a sample of 52 people. The research method used is multiple linear regression analysis. The results of the calculation of the partial hypothesis testing obtained the organizational culture value of 3,264 > ttebel (2,010) or the probability of sig (0,000) < 0,05, promotion (2,648) > (2,010) or probability sig (0,002) < 0,05,career development (4,966) > (2,010) or probability sig (0,003) < 0,05and the value of fcount (10,451) > Ftable(2,79) or probability sig (0,000) < 0,05. So the variables of organizational culture, job training and career development simultaneously have an effect or positively and significantly on employee performance variables at PT. Perkasa Internusa Mandiri Medan. The results of the test of the coefficient of determination obtained R Square sebesar 0,85. The indicates that 85% of organizational culture variables, job training and career developnent are able to explain the performance variables of cloud employees at PT. Perkasa Internusa Mandiri Medan the rest 15% (100% - 85%) is an influence. Fro,other unexplained independent variables such as work discipline variables such as work discipline variables and employee motivation.
Keyword: Organizational Culture, Job Training, Career Development and Employee Performance
Pengaruh Aktiva Tetap, Persediaan, Hutang dan Beban Penjualan terhadap Laba Bersih pada Perusahaan Perdagangan Besar Yang Terdaftar di Bursa Efek Indonesia Periode 2016-2019
Authors: Afiezan Adam , Sitorus Minar Register , Lumbantobing Juwita Melissa 
Published: March 2023

The present study is a quantitative one aimed at determining the effect of fixed asset, inventory, liability and sale cost on net profit of large trading companies. The population includes 62 large trading companies listed on Indonesia Stock Exchange within period of 2016-2019. The sampling method used a purposive sampling method with certain criteria by which there were 15 companies obtained so that there were 60 emittent for 4 years. The data is secondary data obtained from www.idx.co.id. The collected data were then analyzed by using a multiple linear regression analysis. The result of the study shown that fixed assets, inventories, liabilities and selling expenses simultaneously have a significant effect on net income. It is indicated by F-Count (27.256) > F- table (2.38) and sig-p (0,000) < 0,05. Fixed asset partially has a significant effect on net income. Inventory partially has a significant effect on net income. Liability partially does not have a significant effect on net income. Selling expenses partially has a significant effect on net income. It is suggested to the trading companies to pay more attention to aspects that affect good profit so that Net Profits can be further increased.
Keywords : Fixed Asset, Inventory, Liability and Sale Cost.
Pengaruh Motivasi, Disiplin Kerja Dan Lingkungan Kerja Terhadap Kinerja Karyawan PT IDK Adam Malik Medan
Authors: Asa Putri , Damayanti Seraphina 
Published: March 2023

This lstudy laims lto lanalyze lthe limpact lof lmotivation, lwork ldiscipline land lwork lenvironment lon lemployee lperformance latlPT lIDK lAdam lMalik lMedan. lThe lpopulation lis l235 lpeople land lthe lsample lin lthis lstudy lis l148 lpeople. lTesting lusinglmultiple llinear lanalysis ltechniques lpartial lhypothesis ltest lresults lobtained lthat lmotivation lhas la lvalue lof ltcount> lttablelthat lis l3.771> l1.65521 lwith la lsignificant llevel lof l0.000 l<0.05, lwork ldiscipline lhas la lvalue lof ltcount> lttable lthat lis l6.177>l1.65521 lwith la lsignificant llevel l0.000 l<0.05 land lthe lwork lenvironment lhas la lvalue lof ltcount> lttable lthat lis l4.184 l>l1.65521 lwith la lsignificant llevel lof l0.000 l<0.05 lso lthat lmotivation, lwork ldiscipline land lwork lenvironment lhave la lpositiveland lsignificant leffect lon lemployee lperformance lat lPT lIDK lAdam lMalik lMedan. lSimultaneous ltest lresults lobtained lthat lthelvalue lof lFcount l> lFtable lof l135,077> l2.67 lwith la lsignificant llevel lof l0.000 l<0.05 lso lthat lit lcan lbe lconcluded lthatlmotivation, lwork ldiscipline land lwork lenvironment lhave la lsignificant land ljoint leffect lon lemployee lperformance lat lPT lIDKlAdam lMalik. lMedan. lObtaining lthe lcoefficient lof ldetermination ltest lobtained lan ladjusted lr lsquare lvalue lof l0.732 lorl73.2% lwhich lmeans lthat lmotivation, lwork ldiscipline land lwork lenvironment lonly lexplain lvariations lin lteacherlperformance lvariables lby l73.2% land lthe lremaining l26.8% lis linfluenced lby lother lvariables loutside lthe lvariable. lthislresearch.
Keywords: Motivation, Work Discipline, Work Environment, Employee Performance
Pengaruh Modal Kerja Dan Likuiditas Terhadap Profitabilitas
Authors: Sarifah Siti , Hapsari Nesti , Diana Nana 
Published: March 2023

The purpose of this research is to find out and analyze the effect of working capital and liquidity on profitability, either partially or simultaneously. The method in this study uses descriptive and verification methods, this research begins by using the analysis of working capital as a variable X₁. Then Liquidity as a variable X₂. And finally Profitability as variable Y. The population in this study is all food companies and the minimum listed on the Indonesia Stock Exchange (IDX) in the period 2013-2019. The sampling technique used in this research is non-probability sampling with purposive sampling technique. Based on the sampling criteria as described above, the number of samples used in this study were 6 companies. The results of the research partially prove that the working capital variable has an effect on Return On Equity, the results of the partial test prove that the variable Current Ratio has an effect on Return On Equity and the research results simultaneously (together) Working Capital and Current Ratio have a significant effect on Return On Equity in food and beverage companies listed on the IDX for the period 2013-2019.

Keywords: CR, Working Capital, ROA