bluuebunny/crossref_metadata_2025_split huggingface dataset:
TELLURO-INDUCED CYCLISATION 2-(BUT-2-ENYLTHIO)QUINOLINECARBALDEHYDE AND QUINOLINE-4-ONE
Authors: Sabo T. , Kut D. , Kut M. , Onysko M. , Lendel V. 
Published: May 2023

Aryltellurium trichlorides have proven themselves as good cyclizing reagents in electrophilic intramolecular cyclization reactions, mainly of propenyl derivatives of heterocycles. On the other hand, information on the use of butenyl derivatives in reactions with p-alkoxyphenyltellurtrichlorides is limited. In this work, the regioselectivity of the process of electrophilic intramolecular cyclization of but-2-enyl thioethers of quinoline-3carbaldehyde and quinazolin-4-one with p-methoxyphenyltellurium trichloride was investigated.
It was established that, as a result of the tellurium-induced cyclization with p-methoxyphenyltellurium trichloride of but-2-enyl thioethers of quinoline and quinazoline, angular tricyclic chlorides – 2-(dichloro(4-methoxyphenyl)-tellanyl)-1-methyl-5-formyl-2,3- dihydro-1H-[1,3]thiazino[3,2-a]quinolin-11-ium and 2-(dichloro(4-methoxyphenyl)-tellanyl)-1-methyl-6-oxo-5-phenyl-2, 3,5,6-tetrahydro-1H-[1,3]thiazino[3,2-a]quinazolin-11-ium, respectively, with an annealed six-membered ring in the form of complexes with p-methoxyphenyltellurium trichloride. Optimal conditions for the electrophilic intramolecular cyclization reaction were selected.
Keywords: electrophilic heterocyclization; p-methoxyphenyltellurium trichloride; organotellurium compounds; chloride 2-(dichloro(4-methoxyphenyl)-tellanyl)-1-methyl-5-formyl-2,3-dihydro-1H-[1,3]thiazino[3,2 -a]quinolin-11-ium, chloride 2-(dichloro(4-methoxyphenyl)-tellanyl)-1-methyl-6-oxo-5-phenyl-2,3,5,6-tetrahydro-1H-[1,3]thiazino[3,2-a]quinazolin-11-ium
SYNTHESIS OF TERMINAL 2-ALKENYL(ALKYNYL)THIO-5-CYANO-6-(p-DIMETHYLAMINOPHENYL)PYRIMIDIN-4-ONES
Authors: Povidaichyk M. , Onysko О. , Onysko M. 
Published: May 2023

Functionalized pyrimidines possess a wide spectrum of biological activity. In particular, they have antitumor, antiviral, and anticonvulsant activities, exhibit anti-inflammatory and analgesic effects, and they are inhibitors of aldose reductase, SecA ATPase, azide, and plant growth. The search for methods of synthesis of new functionalized and condensed pyrimidine derivatives is an urgent problem.
Alkenyl-functionalized mono- and polycyclic pyrimidines are promise substrates for studying the regioselectivity of electroph ilic heterocyclization reactions under the influence of halogen-containing electrophilic agents, and halogen- and chalcogen-functionalized cyclization products showed high antibacterial, antifungal, and antimalarial activity. The introduction of new functional groups capable to modification into such alkenylpyrimidines can significantly affect their reactivity and change/enhance the biological activity of the halocyclization products. We proposed the synthesis of 2-alkenyl(alkynyl)thio derivatives of 5-cyano-6-(p-dimethylaminophenyl)-pyrimidin-4-one containing a cyano group labile to functionalization. As a result of alkylation of 2-thioxo-5-cyano-6-(p-dimethylaminophenyl)pyrimidin-4-one with unsaturated alkyl halides in an alkaline medium, the terminal alkenyl (allyl, methallyl) and alkynyl (propargyl) thioethers of cyanopyrimidine were obtained, promising for heterocyclization with halogen-containing electrophilic reagents .
Keywords: 2-thioxo-5-cyano-pyrimidin-4-one; alkylation; alkenylthiopyrimidinone; alkynylthiopyrimidinone.
THE ROLE OF TEACHING ASSIGNMENTS IN CHEMISTRY IN THE CONTEXT OF PERSONALLY ORIENTED EDUCATIONAL ACTIVITY
Authors: Dzyamko V.M. , Dzyamko Yo. , Stercho I.P. , Batko A.V. 
Published: May 2023

Today requires modernization of the education system. The main attention in the state doctrine of education development is focused on the personality, and this requires the implementation of certain changes and even a complete restructuring of classical methodological approaches to raising. In the today's realities conditions, it is necessary to take into account the decreasing of the skills and knowledge level of students on all school subjects, including chemistry. Educational tasks play an important role in the education system. However, in distant learning, the role of each type of educational tasks increases significantly. The method of using educational tasks during the study of chemistry in a secondary school was analyzed, and the disadvantages of traditional methods were revealed. Ways to solve this problem are proposed.
The main criteria and indicators were determined, according to which the pedagogical effectiveness of the designed methodology was checked, including the self-reflection of personal educational achievements. Better academic performance and motivation of the experimental class was established, as the vast majority of students have achieved a high and sufficient level of knowledge quality. The growth of the comfort index and the level of self-assessment of personal educational achievements in the experimental class compared to the control class was shown. It has been demonstrated that such indicators as the ability to self-reflect personal educational achievements, the ability to solve chemistry assignments for students of the experimental class are also higher than in the control class.
Keywords: educational assignments; questions; exercises; problems; chemistry; educational activity.
A fresh look at sports PSM-systems
Authors: Savostyanov Vladimir , Kobelev Alexander , Govorin Anton 
Published: May 2023

Abstract
The aim of the proposed study is to reveal the correlations between the dynamics of Respiratory Rate (RR) and Heart Rate (HR) during intermittent physical work at maximum power on a cycle ergometer. The stage of investigating the General functional athlete readiness (GFAR) was conducted using the sports standard “R-Engine” and the cycle ergometer in 16 volunteers (10 men, 6 women) whose average age was 21±1.17 years. To determine the athletic potential of the volunteers in this study, we used our own Coefficient of Anaerobic Capacity (CANAC Q, beats). Continuous registration of the heart rate and respiratory rate of volunteers in the maximum power sports test was performed by the “RheoCardioMonitor” system with a module of the athlete functional readiness based on the method of Transthoracic electrical impedance rheography (TEIRG). The degree of correlation of functional indicators (M, HRM, GFAR) with CANAC Q in all experimental series of the study group as a whole (n=80) was at a very high level, which confirmed the effectiveness of using the Coefficient of Anaerobic Capacity (CANAC Q) in assessing the general functional athlete readiness of the volunteers. CANAC Q is measured in “beats” of the heart and is recorded very accurately using the method of transthoracic electrical impedance rheography (TEIRG). For this reason, as a promising sports PSM-system, CANAC Q can replace the methods for determining the functional athlete readiness by blood lactate concentration and maximum oxygen consumption.
Faktor-Faktor Pendukung Dan Penghambat Dalam Menghafal Al-Qur’an
Authors: Simanjuntak Dahliati 
Published: May 2023

In this life, there is no achievement without trials and tribulations. With these tests and trials will be found and determined who wins and who loses. Similarly, in memorizing the Qur'an, it becomes a necessity that there are tests and trials that will distinguish the achievements of one person from another and determine the final results achieved by each of them. The problems of students in memorizing can be distinguished into problems that come from within (internal) and problems that come from outside (external). Internal problems in the form of many disobediences, feeling lazy, impatient, hopeless, memorized verses forgetting again, difficulty managing time, physical and spiritual fatigue. Meanwhile, external problems are related to the relationship between students and the physical and social environment. The physical environment of the pesantren such as room conditions, lighting, air circulation and cleanliness. While the social environment such as relationships with friends, parents, teachers and caregivers. Problems that can often hinder someone from memorizing the Qur'an include problems that come from within (internal factors) and problems that come from outside (external factors).
TINJAUAN HUKUM PROGRESIF TERHADAP PEMBERIAN WASIAT WAJIBAH BAGI AHLI WARIS NON-MUSLIM
Authors: Siregar Fatahuddin Aziz 
Published: May 2023

This study aims to describe the problem of determining compulsory wills for non-Muslim heirs, this will be studied using a progressive legal perspective. While the type of research used is qualitative research and is supported by literature research and uses a normative-juridical approach. The results of this study showed that the panel of judges of the Supreme Court considered that non-muslim heirs were entitled to a mandatory testamentary share of 1/4 or 25% of the property left by the testator. The reason is, heirs often accompany heirs both in good health, illness, and anything else entered when heirs seek treatment in China until heirs are willing to accompany them. Therefore, the practice of giving a compulsory will is a form of substantive justice to heirs as is characteristic of progressive law. Moreover, justice according to progressive law, it is not the state that asserts mechanisms but substantive justice.
Advantages of selective ischemia and indocyanine green fluorescence navigation in laparoscopic partial nephrectomy: preliminary results
Authors: Molchanov R.M. , Goncharuk О.О. , Blyuss О.B. 
Published: May 2023

An important stage of the nephron-sparing surgery for the treatment of kidney tumors is the temporary creation of thermal ischemia, which can lead to a further decrease in kidney function, therefore this stage needs to be optimized. The aim of our work was to investigate the benefits of using segmental ischemia using intraoperative indocyanine green (ICG) navigation for kidney resection in patients with kidney tumors. The prospective study included 73 patients diagnosed with a kidney tumor who underwent partial nephrectomy (PN). Patients were divided into three groups, according to the use of the thermal ischemia method: total ischemia by clamping the main renal artery (n=33), segmental ischemia by clamping the segmental artery with the use of ICG navigation (n=26), and without it (n=16). Demographic, physiological, and perioperative data were analyzed for all patients. Before and on the fourth day after surgery, the glomerular filtration rate was evaluated according to the level of blood creatinine – eGFR (calculated glomerular filtration rate (eGFR). Multiple linear regression was used to model the effect of variables on change in eGFR. The data testify to the significant index difference in eGFR level change on the fourth postoperative day in the groups of total and segmental ischemia in favor of the latter (p=0.001). A decrease in eGRF was associated with the length of hospital stay (p=0.021). The data stratification in tumor size showed that it is the most important factor defining eGFR level change during total or segmental ischemia application. Renal tumor localization influences eGFR level change during the postoperative period for a maximum diameter of <40 mm tumors. However, for >40 mm diameter tumors, the statistically significant index of eGFR deviation was not found. At the same time, in the patient group with >40 mm tumors, there was a notable difference in eGFR deviation among the groups of total and segmental ischemia (about 15 mL/min/1.73 m2). In the early postoperative period (up to 4 days) after partial nephrectomy using selective warm ischemia, less pronounced eGFR deviations are observed compared to total warm ischemia. Tumor size and its localization are the risk factors for eGFR level decline in the early postoperative period. We did not find any statistically significant differences in intra- and early postoperative indexes for groups II and III patients where segmental ischemia was applied either with indocyanine green fluorescence imaging or without it.
Dynamics of SARS-CoV-2 seroassay sensitivity: a systematic review and modelling study
Authors: Owusu-Boaitey Nana , Russell Timothy W , Meyerowitz-Katz Gideon , Levin Andrew T , Herrera-Esposito Daniel 
Published: May 2023

Background
Serological surveys have been the gold standard to estimate numbers of SARS-CoV-2 infections, the dynamics of the epidemic, and disease severity. Serological assays have decaying sensitivity with time that can bias their results, but there is a lack of guidelines to account for this phenomenon for SARS-CoV-2.

Aim
Our goal was to assess the sensitivity decay of seroassays for detecting SARS-CoV-2 infections, the dependence of this decay on assay characteristics, and to provide a simple method to correct for this phenomenon.

Methods
We performed a systematic review and meta-analysis of SARS-CoV-2 serology studies. We included studies testing previously diagnosed, unvaccinated individuals, and excluded studies of cohorts highly unrepresentative of the general population (e.g. hospitalised patients).

Results
Of the 488 screened studies, 76 studies reporting on 50 different seroassays were included in the analysis. Sensitivity decay depended strongly on the antigen and the analytic technique used by the assay, with average sensitivities ranging between 26% and 98% at 6 months after infection, depending on assay characteristics. We found that a third of the included assays departed considerably from manufacturer specifications after 6 months.

Conclusions
Seroassay sensitivity decay depends on assay characteristics, and for some types of assays, it can make manufacturer specifications highly unreliable. We provide a tool to correct for this phenomenon and to assess the risk of decay for a given assay. Our analysis can guide the design and interpretation of serosurveys for SARS-CoV-2 and other pathogens and quantify systematic biases in the existing serology literature.
(Re) Constructing ‘Subservient’ Filipino Migrant Subjectivities
Authors: Gelvezon Fea Jerulen 
Published: May 2023

In the 1970s, the Philippine state implemented a labour-export policy to alleviate the country’s economic crisis. This policy centres the needs of employers at the expense of the rights and lives of Filipino migrants. As a consequence, many Filipino migrants find themselves in low-paying, precarious, and exploitative working conditions. However, as foreign employment of Filipino labour is tied to the state’s economic agenda, the Philippine state is caught between protecting the rights of its citizens and economic profits. In this essay, I argue that the Philippine state constructs ‘docile’ and ‘subservient’ migrant subjectivities to serve the state’s neoliberal interests. Although, as migrants learn to become acutely aware of their exploitation, they re-construct a subjectivity premised on challenging the Philippine state’s neoliberal interests through the help of transnational migrant activist groups.

This essay employs a qualitative case study analysis of the Philippines’ foremost institution serving migrants, the Philippine Overseas Employment Agency (POEA) and the largest transnational Filipino migrant activist group, Migrante International. I use a Critical Filipino Studies (FilCrit) framework to analyze these case studies. FilCrit recognizes that the institutionalization of migration under US colonization largely influences how Filipinos are incorporated into the global economy to this day. This essay finds that the goals of the Philippine state and migrant activist groups stems from their opposing values. The Philippine state is concerned about its neoliberal agenda, while migrant activist groups are concerned with Filipino migrants’ everyday lives.
Analisis Unsur Diskresi Dalam Instruksi Presiden Nomor 1 Tahun 2022
Authors: Kaharudin Kaharudin , Amalia Riska Ari 
Published: May 2023

Melalui Instruksi Presiden Nomor 1 Tahun 2022 tentang Optimalisasi Pelaksanaan Program Jaminan Kesehatan Nasional, Pemerintah menginstruksikan kepada 30 (tiga puluh) Kementerian/Lembaga untuk menindaklanjuti agar kepesertaan BPJS menjadi syarat wajib dalam pelayanan publik. Instruksi tersebut merupakan peraturan kebijaksanaan yang berisi diskresi dalam menafsirkan UU SJN dan UU BPJS.Â Tujuan dari penelitian adalah untuk mengetahui diskresi memiliki Batasan dan untuk mengetahui instruksi presiden tersebut memenuhi syarat diskresi. Metode penelitian yang digunakan adalah penelitian hukum normatif dengan pendekatan peraturan perundang-undangan dan pendekatan konsep yang ditunjang oleh bahan hukum primer dan bahan hukum sekunder. Berdasarkan hasil penelitian bahwa diskresi dibatasi AAUPB dan asas legalitas, serta Inpres Nomor 1 Tahun 2022 tidak memenuhi syarat diskresi karena bertentangan dengan ketentuan dalam UU No. 25 Tahun 2009 tentang Pelayanan Publik.
Penyuluhan Hukum Tentang Kekuatan Pembuktian Akta Hibah Di Desa Ongko, Kecamatan Empang, Kabupaten Sumbawa
Authors: HS. Salim , Djumardin Djumardin , Munandar Aris 
Published: May 2023

Tujuan kegiatan penyuluhan hukum ini, adalah untuk meningkatkan pemahaman masyarakat tentang (1) kekuatan pembuktian akta hibah yang dibuat di hadapan notaris atau PPAT, dan (2) upaya-upaya yang harus dilakukan untuk meningkatkan pemahaman masyarakat tentang prosedur dalam pemberian hibah. Metode yang digunakan dalam kegiatan penyuluhan hukum ini adalah metode ceramah dan dialog. Metode ceramah digunakan untuk menyampaikan materi penyuluhan kepada peserta penyuluhan. Sedangkan metode dialog adalah metode untuk memberikan kesempatan kepada peserta untuk menyampaikan hal-hal yang kurang lengkap dan kurang jelas tentang materi penyuluhan hokum. Kegiatan penyuluhan hukum tentang kekuatan pembuktian akta hibah di desa Ongko, Kecamatan Empang, Kabupaten Sumbawa telah dilaksanakan pada tanggal 5 September 2022; peserta penyuluhan berjumlah 33 orang; materi penyuluhan terdiri atas: kekuatan pembuktian akta hibah, dan landasan hukum, subjek dan objek akta hibah Dampak positif kegiatan penyuluhan hukum ini,adalah:meningkatnya pemahaman masyarakat tentang kekuatan pembuktian akta hibah; dan landasan hukum, subjek dan objek akta hibah.
PENANGANAN KONFLIK AGAMA DI KOTA JAMBI BERBASIS KEBIJAKAN PUBLIK
Authors: Halim Abdul 
Published: May 2023

This research seeks to analyze the policy of Jambi City Government in handling of religious conflict, especially the establishment of worship place, in Jambi City. This research adopted qualitative approach with case study of research type. Jambi City is a religiously plural area that has experienced conflicts over the establishment of worship places. Because of this, the Jambi City Government issued a policy of intensive coordination with religious leaders, peaceful conflict resolution, verification of permits for worship places and development of tolerance villages. These policies are intended so that religious conflicts that commonly occur in plural societies do not continue and threaten the harmonization of society. This research is scientifically and practically significant since it: Contributes to enriching the theoretical aspect of the academic studies on public policy in the reality of the government’s role and its use of this model in managing public areas, especially in religion. This research completely discussed the perceptions about the tracks of the government’s role and the extent of use of realism in public policy, especially in the religious conflict. As well as define the realist conditions, means, methods, and tools adopted by the researchers in strengthening the public policy theory to achieve study of government’s role in handling public problems, especially in religious conflict.
Penelitian ini berupaya menganalisis kebijakan Pemerintah Kota Jambi dalam penanganan konflik agama khususnya pendirian rumah ibadah di Kota Jambi. Penelitian ini mengadopsi pendekatan kualitatif dengan jenis penelitian studi kasus. Kota Jambi merupakan daerah yang majemuk beragama yang mengalami konflik pendirian rumah ibadah. Karena itu, Pemerintah Kota Jambi mengeluarkan kebijakan koordinasi intensif dengan tokoh agama, penyelesaian konflik secara damai, verifikasi izin tempat ibadah dan pengembangan kampung toleransi. Kebijakan tersebut dimaksudkan agar konflik keagamaan yang lazim terjadi dalam masyarakat majemuk tidak berlanjut dan mengancam harmonisasi masyarakat. Penelitian ini signifikan secara ilmiah dan praktis karena: Berkontribusi untuk memperkaya aspek teoretis kajian akademik tentang kebijakan publik dalam realitas peran pemerintah dan penggunaan model ini dalam mengelola ruang publik, khususnya dalam bidang agama. Penelitian ini secara lengkap membahas persepsi tentang jejak peran pemerintah dan sejauh mana penggunaan realisme dalam kebijakan publik, khususnya dalam konflik agama. Serta menentukan kondisi realis, cara, metode, dan perangkat yang digunakan peneliti dalam memperkuat teori kebijakan publik untuk mencapai kajian peran pemerintah dalam menangani masalah publik, khususnya dalam konflik agama.
Pendampingan Mengatasi Kecanduan Gadget Pada Anak Perspektif Islam
Authors: Amiliya Reni , Giantara Febri , Witanti Kaminem , Susanti Safari Amami , Sulasmi Sulasmi , Lena Widya Sastra , Hasanah Robingatun , Chrityanti Desita Merry , Rohma Ulva Hidayatuh 
Published: May 2023

Orang tua zaman sekarang pada umumnya memberikan gadget kepada anak mereka sejak usia dini. Berbagai macam alasan disampaikan oleh orang tua. Dimulai dari kesibukan karena banyaknya aktivitas yang harus dilakukan, agar anak diam, tidak mau direpotkan oleh keaktifan anak dan lain sebagainya. Pemberian gadget pada anak-anak sudah berada pada tahap yang mengkhawatirkan. Hal ini dapat dilihat dari banyaknya anak yang kecanduan gadget. Pelatihan mengatasi kecanduan gadget atau ADIKSI pada anak sangat banyak dan mudah untuk diakses sekarang ini. Bisa dilakukan secara online atau pun offline. Tetapi belum banyak pendampingan terhadap ADIKSI gadget pada anak dari perspektif Islam. Pendampingan dan pelatihan pendampingan ADIKSI gadget pada anak berwawasan Islam yang dilaksanakan oleh Dosen dan Mahasiswa IAI Diniyyah Pekanbaru pada tanggal 01-10 Agustus 2022 dengan menggunakan pendekatan Service Learning. Kegiatan ini membuahkan motivasi dan minat orang tua dan wali siswa PAUD/PIAUD di Desa Suka Damai Kecamatan Singingi Hilir Kabupaten Kuansing-Riau untuk mengatasi ADIKSI pada anak secara Islami.

Today's parents generally give gadgets to their children from an early age. Various reasons were given by parents. Starting from being busy because of the many activities that must be done, so that the child is quiet, does not want to be bothered by the child's activity, and so on. Giving gadgets to children is already at an alarming stage. This can be seen from the number of children who are addicted to gadgets. Training for overcoming gadget addiction or ADDICTION in children is numerous and easy to access nowadays. Can be done online or offline. But there hasn't been much assistance for gadget addiction in children from an Islamic perspective. Assistance and training on gadget addiction assistance for children with an Islamic perspective which was carried out by Lecturers and Students of IAI Diniyyah Pekanbaru on 01-10 August 2022 using the Service Learning approach. This activity resulted in the motivation and interest of parents and guardians of PAUD/PIAUD students in Suka Damai Village, Singingi Hilir District, Kuansing-Riau Regency to overcome ADIKSI in children in an Islamic way.