bluuebunny/crossref_metadata_2025_split huggingface dataset:
G.M. Burov - a discoverer and initiator of the Mesolithic studies in the European North-East
Authors: Volokitin A. , Volokitina N. , Rodov S. 
Published: May 2023

Grigory M. Burov (22.09.1933 - 24.02.2013), a graduate of the Kiev University, arrived in Syktyvkar in 1957. He worked in the Komi Branch of the Academy of Sciences of the USSR until 1968. Subsequently, he worked in Ulyanovsk and Simferopol.
However, the period of his work in the Komi Region turned out to be the most productive .G.M. Burov is a discoverer of numerous sites of the Mesolithic, Early Metal and Early Iron Age of the previously unexplored Vychegda territory. G.M. Burov analyzed and published materials from Komi all the subsequent years of his life.
The Vis 1 (Mesolithic) and Vis 2 (mid I millennium A.D.) peatbogs discovered by G.M. Burov in the vicinities of the Sindor village have gained worldwide fame. The exemplary paleogeographic studies were carried out in the Sindor microregion. The leading geobotanist and peat specialist S.N. Tyuremnov and other scientists compiled pollen diagrams, described profiles of peatlands, restored the historical courses of the Vis and Simva Rivers. They also obtained a series of direct radiocarbon datings of wooden artifacts.
A unique collection of items made of wood, bark, and grass was obtained at the Vis 1 peatbog. It included fishing tools - fragments of nets and a fishing spear; hunting tools - bows, arrows, a spear; means of transportation - skis, sledge runners, a paddle; household items including a box of birch bark, mats of wood shakes. Many items are decorated with carved geometric ornaments. The sculptural head of an elk on one of the skis is particularly noteworthy.
G.M. Burov was the first of the researchers who justified the cultural differentiation of the Mesolithic sites of the European North-East. He identified two cultural types: the Kama-Pechora type dating back to the VIII-VII millennium B.C., and the Vis type (the second half of the VII-VI millennium B.C.). The Middle Vychegda Mesolithic culture identified by him belongs to the Kama-Pechora type.
Hunting pits of Eastern Fennoscandia: archaeology and ethnography
Authors: Shahnovich M. 
Published: May 2023

The purpose of the work is to analyze the method of hunting for large animals using trapping pits. These interesting archaeological artifacts are known in the tundra and North taiga zone of Northern Eurasia. The paper deals with the main problems of the initial stage of their study.
In the European part of Russia, the trapping pits were studied insignificantly. Extensive work was carried out in Sweden, Norway, and Finland. The pits were dug and provided with special long fences. The main huntable animals were reindeer and elk. In Russia, the trapping pits are known from the Karelian Isthmus to the Barents Sea. They were used from the Mesolithic to the XVI century. In the Middle Ages in Fennoscandia, the traps could be made by aborigines, Sami, and neighboring groups as Karelians, Finns, Germans. Against a comprehensive study of ethnography and archeology, the hunting pits are good informative archaeological assets.
Mesotelioma Peritoneal Maligno - Um relato de caso
Authors: Taveira Eliseu José Fleury , Santana Lanúscia Morais de , Rosa Victor Domingos Lisita , Gabriel Augusto Ribeiro , Vega Maria Cecilia Monteiro Dela , Azevedo Fernando Santos de , Gomes Arthur Moreira 
Published: May 2023

Resumo
Introdução: o Mesotelioma Peritoneal Maligno (MPM) é uma doença rara e letal com variável grau de agressividade. A morbimortalidade está relacionada com a carga de doença tumoral e a sobrevida mediana sem tratamento é de cerca de 12 meses. Quimioterapia baseada em cisplatina é o tratamento padrão nos casos de doença avançada irressecável, ou nos pacientes que declinam cirurgia, associado a quimioterapia hipertérmica intraperitoneal (HIPEC). Desenvolvimento: paciente, 54 anos, com histórico de perda ponderal, desconforto e aumento progressivo de volume abdominal, com imagem evidenciando espessamento peritoneal difuso e ascite, foi submetido a laparoscopia e biópsia com achados positivos para MPM, sendo realizada quimioterapia de 3ª linha com cisplatina e gemcitabine, seguido de manutenção com gemcitabine, apresentando resposta completa, sendo, portanto, caso de resposta excepcional e atípica para doença. Considerações finais: Apesar dos fatores de prognóstico desfavoráveis e rápida progressão aos esquemas iniciais, o paciente do caso apresentou melhora clínica importante e ausência de doença mensurável com esquema de cisplatina e gemcitabine, seguido de gemcitabine de manutenção. Comparado com dados vigentes na literatura, tal resposta é excepcional e atípica, haja vista as características biológicas tumorais da doença.
Palavras-chave: Neoplasias Peritoneais; Oncologia; Antineoplásicos Alquilantes; Antimitóticos
Abstract
Objective: Malignant peritoneal mesothelioma (MPM) is a rare and lethal disease with variable degree of aggressiveness. Morbidity and mortality are related to the burden of tumor disease and median survival without treatment is about 12 months. Cisplatin-based chemotherapy is the standard of treatment in cases of advanced unresectable disease or in patients who decline surgery associated with intraperitoneal hyperthermic chemotherapy (HIPEC). Development: a 54-year-old patient with a history of discomfort, progressive increase in abdominal volume and weight loss, with an image showing diffuse peritoneal thickening and ascites, underwent laparoscopy and biopsy with positive findings for MPM, undergoing 3rd-line chemotherapy with cisplatin and gemcitabine, followed by maintenance with gemcitabine, showing a complete response, therefore being an exceptional and atypical response to disease. Final considerations: Despite the unfavorable prognostic factors and rapid progression to the initial regimens, the patient showed significant clinical improvement and absence of measurable disease with cisplatin and gemcitabine regimen, followed by maintenance gemcitabine. Compared with data from the literature, exceptional and atypical presentation, due to the tumor's biological characteristics of the disease.
Keywords: Peritoneal Neoplasms; Medical Oncology; Antineoplastic Agents, Alkylating; Antimitotic Agents
RELATO DE CASO: RECIDIVA LEISHMANIOSE VISCERAL GANGLIONAR EM UM PACIENTE COINFECTADO PELO VÍRUS DA IMUNODEFICIÊNCIA HUMANA
Authors: Benicio Bossler Caroline , Farias Porto Letícia Fernanda , Veloso Costa Coutinho Olivia Maria 
Published: May 2023

Introdução: Leishmaniose Visceral (LV) é uma zooantroponose endêmica no país. O Vírus da Imunodeficiência Humana (HIV), causa imunodepressão que predispõe à coinfecção LV-HIV. O objetivo deste estudo é relatar um caso de recidiva de LV acometendo apenas cadeia de gânglios linfáticos difusamente, acompanhado pelo Serviço de Infectologia do Hospital Geral de Palmas. Desenvolvimento: Paciente JHA 34 anos, natural de Bacabal-MA, com diagnóstico anterior em 2013 de HIV e história de LV tratada resolutivamente há 5 meses com Anfotericina B Lipossomal e manutenção com profilaxia secundária. O paciente iniciou acompanhamento há 3 anos junto a Infectologia sendo diagnosticado com LV de caráter ganglionar difuso por meio de biópsia mesentérica. Retornou em fevereiro de 2022 com quadro de adenomegalia difusa (submandibular, cervical, axilar, inguinal), febre moderada, inapetência e perda ponderal a esclarecer. Laboratorialmente paciente apresentava pancitopenia. A tomografia de pelve confirmou o aumento dos gânglios. Com tal evidência, o mesmo foi requerido a internação hospitalar. Durante esse tempo o paciente fez uso de Anfotericina B Lipossomal durante 10 dias e recebeu alta da enfermaria, assintomático com regressão linfonodal e retorno em 15 dias ambulatorialmente para manutenção com profilaxia secundária até CD4 > 350. Considerações Finais: Tal caso, nos confirma que o agente da doença pode permanecer em órgãos do sistema monocítico fagocitário, sendo capaz de permanecer por longo período no indivíduo infectado. Pode ocorrer, devido a diversos fatores que afetam a resistência do hospedeiro, a reativação da doença. Neste caso, o paciente recebeu alta da profilaxia com CD4 > 200 e mesmo assim houve recidiva. Isso ilustra um caso atípico de LV, sem hepatoesplenomegalia e gamaglobulinemia. E reitera a importância do seguimento da profilaxia secundária em pacientes HIV por maior período.

Palavras-chave: Leishmaniose Visceral; Recidiva; Doenças Linfáticas.
Experimental Analysis of the Effectiveness of Sodium Hexametaphosphate as Calcium Carbonate Scales Inhibitor
Authors: Paz Paulo , Netto Theodoro Antoun 
Published: May 2023

Summary
Offshore oil and gas production is known to present severe flow assurance issues, in particular calcium carbonate (CaCO3) scale deposition, as its formation reaction is influenced by temperature and pH changes that occur during production. This study investigated the calcium carbonate scaling process using a newly developed 1-inch diameter mesoscale loop and also the efficiency of sodium hexametaphosphate (SHMP) as a scale inhibitor for calcium carbonate under drastic conditions of temperature, flow rate, and scaling ions concentration. The relationship between flow rate, temperature, experimental time, and CaCO3 formation parameters was evaluated using a dynamic methodology designed for the mesoscale loop. Moreover, scanning electron microscopy (SEM) images and energy-dispersive spectrum (EDS) chemical analysis were used to study changes in the microstructure and the elemental composition of the deposits in the absence and presence of the scale inhibitor. The inhibition effect was found satisfactory, as CaCO3 deposition greatly decreased. The deformed structures of the CaCO3 crystals observed by SEM images and EDS analysis helped visualize the changes due to the SHMP. Finally, the temperature changes due to the accumulation of deposits through thermal images were helpful in explaining what was happening inside the pipes system during the scaling tests.
Hyperreflective Material in Patients with Non-neovascular Pachychoroid Disease
Authors: Maruyama-Inoue Maiko , Yanagi Yasuo , Mohamed Shaheeda , Inoue Tatsuya , Kitajima Yoko , Ikeda Shoko , Kadonosono Kazuaki 
Published: May 2023

Abstract
Background: This study aimed to report eleven cases of non-neovascular pachychoroid disease with hyperreflective material (HRM) that occurred in Japanese patients.
Methods: A retrospective review of data from eleven patients who had non-neovascular retinal pigment epithelium (RPE) protrusion with HRM in the neurosensory retina between March 2017 and June 2022 was conducted. Clinical examination, color fundus photography, fluorescein angiography, spectral-domain optical coherence tomography (SD-OCT), and OCT angiography data were analyzed. Main outcome measureswere patient characteristics, changes in SD-OCT findings, and symptom outcomes.
Results:All cases had RPE protrusion and HRM with dilated choroidal veins, which were characteristic of pachychoroid disease. However, none of the cases had macular neovascularization (MNV). In 9 eyes (81.8%), HRM improved spontaneously without intervention and resulted in alterations in RPE, referred to as pachychoroid pigment epitheliopathy (PPE) or focal choroidal excavation (FCE). In these cases, symptoms such as metamorphopsia and distortion improved without treatment. In the remaining two cases (18.2%), HRM still persisted during the follow-up period.
Conclusion: There are some cases of non-neovascular pachychoroid disorder with HRM, which might be a new entity of pachychoroid spectrum disease or an early stage of PPE or FCE. These cases should not be misdiagnosed as MNV, and careful observation is necessary.
GUP modified Wigner function using classical-quantum unified framework
Authors: Sen Abhijit , Parida Bikram Keshari 
Published: May 2023

Abstract
The generalized uncertainty principle (GUP) is a natural consequence of many proposed
quantum gravity theories which further indicates the modification of the quantum mechanics and
classical mechanics. A unified classical-quantum framework also leads to the interpretation of a
Winger phase-space distribution of a state as a KvN wave function. In this article, we utilize the
classical-quantum unified framework to calculate the expression for the GUP modified Wigner
function of a classical harmonic oscillator in the configuration space instead of the conventional
approach of utilising the momentum space. Further, we plot the modified Wigner functions and
show that they are similar to what has been obtained before in the past literature.
Deformation Evaluation and Displacement Forecasting of Baishuihe Landslide after Stabilization based on Continuous Wavelet Transform and Deep Learning
Authors: Liu Yuting , Teza Giordano , Nava Lorenzo , Chang Zhilu , Shang Min , Xiong Debing , Cola Simonetta 
Published: May 2023

Abstract
Baishuihe Landslide is a large active landslide that threatens shipping transportation in the Three Gorges Reservoir (China). A manual monitoring system has been active since 2003. However, after the realization of some intervention works in 2018-2019, new automatic instruments providing continuous data on displacements, rainfall, reservoir water level, and groundwater table were installed. The data recorded by the new system show that these works led to an effective stabilization improvement since the present displacement rate is lower than that detected before interventions. However, the relevance of the Three Gorges basin and the potential hazard of a possible collapse requires a reliable forecast of the landslide evolution in a time scale from a few hours to a few days. To this aim, a two steps procedure is here proposed. In the first step, after a preliminary preprocessing-denoising of data, carried out by means of Discrete Wavelet Transform (DWT), a Continuous Wavelet Transform (CWT) procedure is used to provide scalograms of the time series of three quantities, e.g., landslide displacement rate, rainfall and the difference of water level between the piezometer and reservoir water level. In the second step, to evaluate the relationships among the velocity trend and the other significant quantities and obtain a reliable velocity forecast, the images given by binding together two or three scalograms of the mentioned quantities were analyzed with a Convolutional Neural Network (CNN) tool. Several trials with different combinations of input time series of 2 or 3 quantities were carried out in order to recognize the factors which mainly affect the current displacement evolution. The results show that, after the works, rainfall is an important factor inducing deformation acceleration. The hydrodynamic pressure induced by the difference between the ground water pressure and reservoir water level also plays a dominant role in accelerating the Baishuihe landslide. Furthermore, the coupling of rainfall and hydrodynamic pressure produces displacement velocities higher than what the quantities singularly do. These results provide valuable indications for optimizing the monitoring configuration on the landslide and obtaining velocity forecasts in a few hours/days.
The effect of family communication on anxiety and depression among adolescents: the mediating role of intimate relationship violence and problematic internet use
Authors: Huang Xin-cheng , Zhang Yue-ning , Wu Xiao-yu , Jiang Yang , Deng Yu-qian , Luo Yuan , Zhao Li-ping , Liu Qin-ling , Luo Sheng-yue , Wang Yan-yan , Jiang Mao-min , Wu Yi-bo 
Published: May 2023

Abstract
[Objective]: The objective of this study is to explore the relationship between family communication, intimate relationship violence, problematic internet use, anxiety, and depression and validate their potential mediating role.
[Methods]: The study population consisted of Chinese adolescents aged 12 to 18 years, and a cross-sectional survey was conducted in 2022. Structural equation models were constructed using AMOS 25.0 software to examine the factors that influence adolescent anxiety and depression and the mediating effects of problematic internet use and intimate relationship violence.
[Results]: The results indicate that family communication was significantly and negatively related to intimate relationship violence (β = -0.309, p < 0.001), problematic internet use (β = -0.039, p < 0.05), depression (β= -0.081, p < 0.001), and anxiety (β = -0.092, p < 0.001). And the finds also indicate that imitate relationship violence mediated the relationships between family communication and depression (β = -0.108, CI: -0.133 -0.087), and between family communication and anxiety (β= -0.098; CI: -0.124 -0.079). Chain indirect effects between family communication and depression (β = -0.051; CI: -0.065 -0.041) or anxiety (β = -0.046; CI: -0.057 -0.037) via imitate relationship violence and then through problematic internet use were also found in the present study.
[Conclusions]: In conclusion, positive family communication is crucial in reducing anxiety and depression in adolescents. Moreover, problematic internet use and intimate relationship violence mediate the effects of positive family communication on anxiety and depression. Therefore, improving family communication and promoting interventions aimed at reducing intimate relationship violence and problematic internet use can help reduce anxiety and depression in adolescents, thus promoting their healthy development.
Self-assembling peptide and nano-silver fluoride in remineralizing early enamel carious lesions: Randomized Controlled Clinical Trial
Authors: Atteya Sara M. , Amer Hala A. , Saleh Susan M. , Safwat Yara 
Published: May 2023

Abstract
Background
Nanoparticles and regenerative biomineralization are new caries prevention technologies. This study assessed the remineralizing effect of self-assembling peptide (P11-4), Nanosilver Fluoride (NSF) and sodium fluoride (NaF) on white spot lesions (WSLs) in permanent teeth.
Methods
Sixty six young adults with WSLs on buccal surfaces in permanent teeth and ICDAS code 1 or 2, were randomly assigned to one of three groups; P11-4, NSF or NaF. Assessment of ICDAS scores, lesion activity and diagnodent readings of lesions were done at baseline and after 1, 3, 6 and 12 months of agents’ application. Comparisons between groups were made using X2 test and comparison within groups were made using McNemar test. Multilevel logistic regression analysis was used to assess the effect of agents on change of ICDAS scores after 12 months.
Results
There were 147 teeth in 66 patients; mean ± SD age = 13.46 ± 4.31 years. There was significant difference in change of ICDAS scores among the three groups after 3 and 6 months (p = 0.005). The regression in ICDAS score increased in all groups in all follow-up intervals with the greatest was among P11-4 group (54.5% after 12 months). Lesion activity assessment has shown significant difference between the three groups with the greatest reduction of lesion activity among the P11-4. Multilevel regression showed non-significant reduction of ICDAS in P11-4 and NSF varnishes compared to NaF varnish (AOR = 2.256, 95% CI: 0.58–8.77 and AOR = 2.119, 95% CI: 0.588,-7.636 respectively).
Conclusion
P11-4 and NSF varnish reduced the ICDAS scores, caries activity and diagnodent readings of WSLs in permanent teeth. However, the change in ICDAS scores was not significantly different from NaF.
Trial Registration
This trial was prospectively registered on the clinicaltrials.gov registry with ID: NCT04929509 on 18/6/2021
Decellularized liver hydrogel enhances cell engraftment in orthotopic hepatocyte transplantation by promoting cell–cell interaction and angiogenesis
Authors: Udagawa Daisuke , Nagata Shogo , Yagi Hiroshi , Nishi Kotaro , Morisaku Toshinori , Adachi Shungo , Nakano Yutaka , Tanaka Masayki , Hori Shutaro , Hasegawa Yasushi , Abe Yuta , Kitago Minoru , Kitagawa Yuko 
Published: May 2023

Abstract
Hepatocyte transplantation (HCT) is a potential bridging therapy or an alternative to liver transplantation. Conventionally, single-cell hepatocytes are injected via the portal vein. This strategy, however, has yet to overcome poor cell engraftment and function. Therefore, we developed an orthotopic hepatocyte transplantation method using a liver-derived extracellular matrix (L-ECM) gel. PXB cells (flesh mature human hepatocytes) were dispersed into the hydrogel solution in vitro, and the gel solution was immediately gelated in 37 ℃ incubators to investigate the affinity between mature human hepatocyte and the L-ECM-gel. During the 3-day cultivation in hepatocyte medium, PXB cells formed cell aggregates via cell–cell interactions. Quantitative analysis revealed human albumin production in culture supernatants. For the in vivo assay, PXB cells were encapsulated in the L-ECM gel and transplanted between the liver lobes of normal rats. Pathologically, the L-ECM gel was localized at the transplant site and retained PXB cells. Cell survival and hepatic function marker expression were verified in another rat model wherein thioacetamide was administered to induce liver fibrosis. Moreover, cell–cell interactions and angiogenesis were enhanced in the L-ECM gel compared to that in the collagen gel. Our results indicate that L-ECM gels can help engraft transplanted hepatocytes and express hepatic function as a scaffold for cell transplantation.
Dynamic accommodation measurement using Purkinje reflections and machine learning
Authors: Ozhan Faik Ozan , Aygun Ugur , Sahin Afsun , Urey Hakan 
Published: May 2023

Abstract
Quantifying eye movement is important for diagnosing various neurological and ocular diseases as well as AR/VR displays. We developed a simple setup for real-time dynamic gaze tracking and accommodation measurements based on Purkinje reflections, which are the reflections from front and back surfaces of the cornea and the eye lens. We used an accurate eye model in ZEMAX to simulate the Purkinje reflection positions at different focus distances of the eye, which matched the experimental data. A neural network was trained to simultaneously predict vergence and accommodation using data collected from 9 subjects as well as synthetic data generated using the eye model. We demonstrated that the use of Purkinje reflection coordinates together with pupil center and shape in machine learning improves the accuracy of the prediction. The proposed system accurately predicted the accommodation with an accuracy better than 0.21D using two-point calibration data in tests performed with 9 subjects in our setup.