bluuebunny/crossref_metadata_2025_split huggingface dataset:
Romania's agricultural workers. Return mobilities and modes of food production
Authors: Anghel Remus Gabriel , Vesalon Lucian , Toma Stefánia 
Published: September 2023

AbstractThis article examines the dynamics of Romanian seasonal migration and its effects on farming and rural areas. We connect labour migration to changes in modes of food production in Western and Eastern Europe. Based on the fieldwork in seven Romanian localities with 40 semi‐structured interviews, we interrogate how seasonal work is shaped by regimes of mobility and economic and social inequalities. Studying the case of Romania's large rural population raises critical questions regarding migration, development and change in rural areas. Answering such questions requires disentangling different categories of seasonal migrants and their return prospects. Looking at how agricultural labour is structured, we examine labour experiences and analyse how migrants' agency operates in precarious contexts. Observing the consequences of seasonal migration and return, we discovered diverging processes of agricultural diversification through entrepreneurialism and a radical change in peasant farming resulting in an increased concentration of farmland.
The role of professional identity and job satisfaction in paediatric nurses' intention to remain employed amidst the COVID‐19 pandemic
Authors: Salaten Eman Fawzy Mohammed Mohammed , Zakaria Abeer Mohammed , Ibrahim Ibrahim Abdullatif 
Published: September 2023

AbstractThe COVID‐19 pandemic has significantly affected nursing, as nurses are crucial in providing healthcare services. Understanding the factors influencing nurse retention is essential for maintaining a strong and long‐lasting workforce because nurse retention is becoming increasingly complex. This study aimed to investigate the influence of professional identity and job satisfaction on the intention to remain employed while also evaluating the levels of professional identity, job satisfaction, and intention to stay among paediatric nurses amidst the COVID‐19 pandemic. This correlational and descriptive study included a stratified sample of 257 paediatric nurses and was guided by the STROBE checklist. Data were collected through valid and reliable questionnaires, which included a nurses' professional identity scale, job satisfaction survey, intention to stay scale, and a demographic questionnaire. Data collection was conducted from January to April 2022. The study was approved by the ethical research committee at the Nursing Faculty – Mansoura University, ensuring adherence to the Helsinki Declaration. The paediatric nurses reported elevated professional identity, moderate job satisfaction, and moderate intention to stay employed with mean scores of 80.35 ± 13.22, 113.70 ± 19.58, and 8.40 ± 3.55, respectively. Multiple regression explained 13.0% of the variation in paediatric nurses' intention to remain employed (F = 18.50, p < 0.001). Professional identity positively correlated with the intention to stay (β = 2.69, p = 0.008). Job satisfaction also had a positive relationship with the intention to stay (β = 3.49, p < 0.001). Healthcare managers should focus on professional identity strategies such as supportive work environments, growth opportunities, and valuing paediatric nurses' contributions. Implementing interventions such as fair compensation, support, and rewards can enhance paediatric nurses' retention and quality of patient care.
Analysis of risk factors of infection in diabetic foot patients
Authors: Hsu Limei , Li Le , Poon Lee Yam 
Published: September 2023

AbstractThis cross‐sectional study assessed the risk factors for infection in 150 diabetic foot patients admitted to the Xiamen University Hospital between October 2020 and October 2022. Patients were categorised as infected (n = 80) or uninfected (n = 70) cohorts. The diabetic foot was evaluated using the American Diabetic Foot Grading system, whereas ulcers were categorised using Wagner's method. Analysed were patient‐specific information, clinical data and risk factors including neuropathy, arterial disease and foot deformities. Our findings revealed no statistically significant differences between infected and uninfected cohorts concerning age, body mass index, gender, duration of diabetes or ankle‐brachial index values (p > 0.05). However, infected group had a higher proportion of smokers and reduced socio‐economic status (p < 0.05). Wagner grades indicated a greater severity in the infected group, with grade 3, grade 4 and grade 5 differing significantly (p < 0.05). Comparative analysis of ulcer characteristics revealed no statistically significant differences in ulcer surface area and depth, but the infected group had a higher prevalence of osteomyelitis and a greater number of ulcers (p > 0.05). Blood vessel complications, retinopathy, the presence of three or more ulcers, osteomyelitis and diabetic nephropathy were substantially more prevalent in the infected group, as determined by univariate analysis (p < 0.05). Subsequent multivariate logistic analysis revealed that patients with blood vessel complications, retinopathy, osteomyelitis, diabetic nephropathy and three or more ulcers were at increased risk for infection (p < 0.05). In addition, lifestyle factors, such as smoking, sedentary behaviour, inadequate foot hygiene, obesity and poor glycaemic control, were also associated with higher infection rates. A multivariate analysis of foot wound factors revealed that deeper, longer and recurrent lesions increased the likelihood of infection. Escherichia coli was the most frequently isolated bacterium from the infected group's bacterial culture, followed by Pseudomonas aeruginosa and Staphylococcus aureus. The study enhanced our comprehension of the multifactorial risk factors associated with infections in diabetic foot patients, highlighting the need for thorough clinical evaluation, lifestyle modification and vigilant infection control.
Patient evaluation of gynaecological information provision and preferences
Authors: Williams Natalie , Griffin Georgia , Wall Megan , Watson Stuart , Warland Jane , Bradfield Zoe 
Published: September 2023

AbstractAimTo evaluate gynaecological patients' preferences and satisfaction regarding information provision, exploring enablers and barriers to information access.DesignA descriptive cross‐sectional survey design was used.MethodsA total of 293 women accessing gynaecological services responded to the survey. Quantitative analysis included descriptive and inferential statistics. Content analysis was conducted on qualitative data.ResultsHealth professionals were the most common and preferred sources of gynaecological health information. Enablers to information provision included positive communication strategies by health professionals, participants having prior knowledge and doing their own research. Despite its widespread availability, only 24.2% of women preferred the internet as an information source. Poor communication and inadequate information provision were identified as barriers to information access. Statistically significant associations were identified between location of residence, education level, year of birth, diagnostic group and health information preferences. Recommendations from women included improved communication strategies, system changes and provision of individualized information.ConclusionHealth professionals are central to women accessing information about gynaecological diagnoses. Areas for improvement include communication strategies, facilitating access to internet‐based resources for information and consideration of women's preferences when providing health information.Implications for the Profession and Patient CareConsumer co‐design of gynaecological health information and communication training for health professionals is recommended. Improved communication and facilitated use of internet‐based resources may improve women's understanding of information.Impact

This study explored gynaecological patients' preferences and satisfaction regarding information provision, exploring enablers and barriers to information access.

It was found that gynaecological patients preferred individualized information provided to them directly by health professionals and despite its widespread availability, the internet is an underutilized health information resource.

These findings are applicable to health professionals and patients utilizing tertiary gynaecological health services in Australia but may be generalized if demographic data aligns with other jurisdictions.

Reporting MethodThe STROBE reporting method was used in the preparation of the manuscript.Patient or Public ContributionNo patient or public contribution.
Transcriptome analysis of six tissues obtained post‐mortem from sepsis patients
Authors: Pinheiro da Silva Fabiano , Gonçalves André Nicolau Aquime , Duarte‐Neto Amaro Nunes , Dias Thomaz Lüscher , Barbeiro Hermes Vieira , Breda Cristiane Naffah Souza , Breda Leandro Carvalho Dantas , Câmara Niels Olsen Saraiva , Nakaya Helder I. 
Published: September 2023

AbstractSeptic shock is a life‐threatening clinical condition characterized by a robust immune inflammatory response to disseminated infection. Little is known about its impact on the transcriptome of distinct human tissues. To address this, we performed RNA sequencing of samples from the prefrontal cortex, hippocampus, heart, lung, kidney and colon of seven individuals who succumbed to sepsis and seven uninfected controls. We identified that the lungs and colon were the most affected organs. While gene activation dominated, strong inhibitory signals were also detected, particularly in the lungs. We found that septic shock is an extremely heterogeneous disease, not only when different individuals are investigated, but also when comparing different tissues of the same patient. However, several pathways, such as respiratory electron transport and other metabolic functions, revealed distinctive alterations, providing evidence that tissue specificity is a hallmark of sepsis. Strikingly, we found evident signals of accelerated ageing in our sepsis population.
Survival of classic and biological systemic drugs in psoriasis: results of the BIOBADADERM registry and critical analysis
Authors: Dávila‐Seijo P. , Dauden E. , Carretero G. , Ferrandiz C. , Vanaclocha F. , Gómez‐García F.‐J. , Herrera‐Ceballos E. , De la Cueva‐Dobao P. , Belinchón I. , Sánchez‐Carazo J.‐L. , Alsina M. , López‐Estebaranz J.‐L. , Ferrán M. , Torrado R. , Carrascosa J.‐M. , Llamas M. , Rivera R. , Jiménez‐Puya R. , García‐Doval I. ,   the BIOBADADERM Study Group
Published: September 2023

AbstractBackgroundFew reported studies compare drug survival in moderate‐to‐severe psoriasis vulgaris.ObjectivesTo describe and compare drug survival of systemic drugs, including biologic agents (infliximab, etanercept, adalimumab and ustekinumab) and classical drugs (acitretin, ciclosporin and methotrexate) in moderate‐to‐severe psoriasis.MethodsThis was a multicenter, prospective, cohort study of patients receiving systemic therapies between 2008 and 2013 in 12 hospitals in Spain. Baseline data and drug discontinuation were collected. Drug survival is presented using Kaplan–Meier survival curves. We compared adjusted risk ratios of serious adverse events (AEs) with results of survival analysis for AEs.ResultsA total of 1956 patients were included for analysis (1240 exposed to biologics during follow‐up and 1076 to classic therapies). Median follow‐up time was 3.3 years (0.0–5.1 years). There were 2209 discontinuations out of 3640 therapy cycles started. The main reason for discontinuation was lack of efficacy (36.4%) and remission (27.2%). Biologics showed a higher drug survival than classics and the pattern of survival results for all outcomes (positive or negative) were very similar. Adjusted risk ratios of serious AEs did not agree with results of survival analysis.LimitationsA limitation is that this is an observational study with potential selection bias.ConclusionSurvival as a proxy measure of drug safety in psoriasis is inadequate.
Role of membrane estrogen receptor alpha (ERα) in the rapid regulation of male sexual behavior
Authors: de Bournonville Catherine , Lemoine Philippine , Foidart Jean‐Michel , Arnal Jean‐François , Lenfant Françoise , Cornil Charlotte A. 
Published: September 2023

AbstractThe activation of male sexual behavior depends on brain estrogen synthesis. Estrogens act through nuclear and membrane receptors producing effects within hours/days or seconds/minutes, respectively. In mice, estrogen receptor alpha (ERα) is the main estrogen receptor (ER) controlling the activation of male sexual behavior. Although neuroestrogens rapidly modulate mouse sexual behavior, it is not known whether these effects involve membrane ERα (mERα). This study combines two complementary approaches to address this question. C451A‐ERα mice carry an ERα that cannot signal at the membrane, while estetrol (E4) is a natural estrogen acting as an agonist on nuclear ERα but as an antagonist on membrane ERα. In wild‐type males, E4 decreased the number of mounts and intromissions after 10 min. In C451A‐ERα males, E4 also altered sexual performance but after 30 min. E4 did not affect time spent near the female in both wild‐type and C451A‐ERα mice. However, regardless of genotype, the aromatase inhibitor 1,4,6‐Androstatriene‐3,17‐dione (ATD) decreased both sexual performance and the time spent near the female after 10 and 30 min, confirming the key role of aromatization in the rapid control of sexual behavior and motivation. In conclusion, the shift in timing at which the effect of E4 is observed in mice lacking mERα suggests a role for mERα in the regulation of rapid effects of neuroestrogens on sexual performance, thus providing the first demonstration that E4 acts as an antagonist of a mER in the brain. The persisting effect of ATD on behavior in C451A‐ERα mice also suggests the implication of another ER.
Predictive factors of post‐operative apathy in patients with diffuse frontal gliomas undergoing awake brain mapping
Authors: Motomura Kazuya , Kawamura Ai , Ohka Fumiharu , Aoki Kosuke , Nishikawa Tomohide , Yamaguchi Junya , Kibe Yuji , Shimizu Hiroki , Maeda Sachi , Saito Ryuta 
Published: September 2023

AbstractPatients with diffuse frontal gliomas often present with post‐operative apathy after tumour removal. However, the association between apathy and tumour removal of gliomas from the frontal lobe remains unknown. This study aimed to investigate the factors influencing post‐operative apathy after tumour removal in patients with diffuse frontal gliomas. We compared the demographics and clinical characteristics of patients with and without post‐operative apathy in a cohort of 54 patients who underwent awake brain mapping for frontal gliomas. The frequency of clinical parameters such as left‐sided involvement, high‐grade tumour types (WHO grades III, IV), main tumour location in the anterior cingulate gyrus (ACC) and/or dorsolateral prefrontal cortex (DLPFC) and orbitofrontal cortex (OFC) was significantly greater in the apathetic group compared to the non‐apathetic group. The apathetic group scored significantly lower on neuropsychological assessments such as the Letter Fluency Test among the Word Fluency Tests than the non‐pathetic group (p = .000). Moreover, the scores of Parts 3, and 3–1 of the Stroop test were significantly lower in the apathetic group than those in the non‐apathetic group (p = .023, .027, respectively). Multivariate model analysis revealed that the appearance of post‐operative apathy was significantly related to side of the of lesion [left vs. right, hazard ratio (HR) = 8.00, 95% confidence interval (CI) = 1.36–46.96, p = .021], location of the main tumour in the frontal lobe (ACC/DLPFC/OFC vs. others, HR = 7.99, 95% CI = 2.16–29.59, p = .002), and the Letter Fluency Test (HR = .37, 95% CI = .15–.90, p = .028). Post‐operative apathy is significantly associated with ACC and/or DLPFC and OFC in the left hemisphere of diffuse frontal gliomas. Apathy in frontal gliomas is correlated with a decline in the Letter Fluency Test scores. Therefore, this instrument is a potential predictor of post‐operative apathy in patients with diffuse frontal gliomas undergoing awake brain mapping.
Epistemic othering: the interplay of knowledges in legislative drafting
Authors: NIEMINEN KATI , SARASOJA LAURA 
Published: September 2023

AbstractIn this article, we use the concept of epistemic othering to describe the subjectivation of people who experience debt problems in the legislative drafting process, and argue that the evidence‐based policy paradigm, together with its participatory dimension, produce a potentially harmful subject position for people who are considered vulnerable and irrational. By analysing the preparatory material of Finnish interest rate cap laws, we explore what is constructed as rational and possible in the legislative process, and how these modalities frame the use of expert knowledge. We argue that what is considered rational is constructed in terms of market logic, and what is construed as possible is heavily framed by law‐as‐knowledge. Together, market logic and law‐as‐knowledge form the preconditions for the use of expert knowledge. Ultimately, the way in which these three types of knowledge interact contributes to the epistemic othering of people who experience debt problems.
Challenging the doctrine of “non‐discerning” decision‐making: Investigating the interaction effects of cognitive styles
Authors: Bakken Bjørn Tallak , Hansson Mathias , Hærem Thorvald 
Published: September 2023

AbstractThe impact of intuitive and analytic cognitive styles on task performance is a much‐debated subject in the scientific discourse on decision‐making. In the literature on decision‐making under time pressure, intuition has been regarded as a fast and frugal tool. At the same time, the heuristics and biases tradition sees intuition as a source of errors, implying that more analytic decision‐makers are less biased and better performers. We conducted two studies of the effects of interplay between intuitive and analytic cognitive styles on decision‐making in a simulated wicked learning environment. The results of the first study revealed that the high‐performing individuals were those who exhibited a strong preference for both cognitive styles, as well as those who showed a lack of preference for both. Individuals with a strong preference for only one of the styles were outperformed. In the second study, we replicated these findings in a team context. Post‐hoc, we found that cognitive ability correlated highly with performance for the two high‐performing style combinations but not for the two low‐performing style combinations. Our results indicate that flexible style preferences boost the effect of cognitive ability, while strong preferences for a single style may entrench even those with high cognitive abilities.
Salivary Biomarkers and Temporomandibular Disorders: A Systematic Review conducted according to PRISMA guidelines and the Cochrane Handbook for Systematic Reviews of Interventions
Authors: Alam Mohammad Khursheed , Zaman Mahmud Uz , Alqhtani Nasser Raqe , Alqahtani Abdullah Saad , Alqahtani Fawaz , Cicciù Marco , Minervini Giuseppe 
Published: September 2023

AbstractBackgroundThe present review aimed to investigate the association between salivary biomarkers and temporomandibular disorders (TMD). TMD is a multifactorial condition characterised by pain and dysfunction in the temporomandibular joint (TMJ) and surrounding structures. Salivary biomarkers have emerged as potential diagnostic tools due to their non‐invasiveness and easy accessibility. However, the literature on salivary biomarkers in relation to TMD is limited and inconsistent.MethodsElectronic databases of Pubmed, Embase, Web of Science, Scopus, Cochrane Library, PsychINFO, CINAHL and Medline were searched using specific search terms and Boolean operators. The search was limited to articles published in English that assessed salivary biomarkers in individuals diagnosed with TMD. Two reviewers independently screened the articles and extracted data. ROB‐2 was used to assess the risk of bias.ResultsEleven clinical papers met the inclusion criteria and were included in the review. The findings provided consistent evidence of a clear association between salivary biomarkers and TMD. Various biomarkers, including cortisol, IL‐1, glutamate and several others, were assessed. Some studies reported higher levels of cortisol and IL‐1 in TMD patients, indicating potential involvement in stress and inflammation. Glutamate levels were found to be elevated, suggesting a role in pain modulation. Other biomarkers also showed alterations in TMD patients compared to controls:ConclusionThe findings from the included studies suggest that salivary biomarkers may play a role in TMD pathophysiology. Though a definitive conclusion can be drawn regarding the specific salivary biomarkers and their association with TMD, the results must be interpreted with caution considering the heterogeneity of the biomarkers assessed. Further research with larger sample sizes, standardised methodology and rigorous study designs is needed to elucidate the role of salivary biomarkers in TMD.
Biomechanical Comparison between Rotational Scarf Osteotomy and Translational Scarf Osteotomy: A Finite Element Analysis
Authors: Li Yan , Wang Yue , Wang Feng , Tang Kanglai , Tao Xu 
Published: September 2023

ObjectiveRotational Scarf osteotomy has its unique advantages in treating hallux valgus, but it also has certain drawbacks. The biomechanical differences between rotational Scarf and translational Scarf osteotomy are not clear evaluates the correction ability and biomechanical difference of two surgical methods for hallux valgus by finite element analysis.MethodsThe computerized tomography data of a hallux valgus patient were selected to establish a finite element model. The standard Scarf osteotomy was simulated based on the model, and the rotation and translation were performed, respectively. The size of the intermetatarsal angle, contact area, distal metatarsal articular angle and the absolute length of the first metatarsal was compared between the two groups. We completed the cartilage, ligament and other tissues on the bone model to establish a full foot model. We analyzed the troughing, plantar aponeurosis tension, plantar soft tissue, and ground stress and also observed the stability of the fracture site by a three‐point bending test.ResultsBoth surgical methods may effectively correct the intermetatarsal angle. After rotational osteotomy, the contact area increased, and the length of the first metatarsal bone initially increased and then decreased compared to that in the translational group. Furthermore, rotational Scarf significantly increased the distal metatarsal articular angle. Mechanical analysis showed that the cancellous bone in the contact part of the fracture site in the translation group had greater stress, which was the reason for the occurrence of the troughing. Stress distribution of plantar aponeurosis, plantar soft tissue, and the ground showed no significant difference. The three‐point bending test showed that the separation of the broken ends of the rotational Scarf osteotomy model (0.133 mm) was slightly smaller than the translational group (0.147 mm).ConclusionBoth surgical methods can successfully correct intermetatarsal angle (IMA). Compared to traditional translational Scarf osteotomy, rotational Scarf osteotomy is more conducive to postoperative stability and healing, but it also has certain drawbacks. In clinical practice, individualized surgical methods still need to be selected for different types of patients with hallux valgus.