bluuebunny/crossref_metadata_2025_split huggingface dataset:
Oxidative stress and antioxidants in health and disease
Authors: Kıran Tugba Raika , Otlu Onder , Karabulut Aysun Bay 
Published: February 2023

Abstract
The increase in the formation of reactive oxygen and reactive nitrogen species of endogenous or exogenous origin causes oxidative stress due to pro-oxidant and antioxidant imbalance that causes cellular damage in metabolism. This can increase inflammation of cells, apoptosis and necrosis, damage to DNA base damage, DNA and protein cross-links, lipid membrane peroxidation, and mitochondrial dysfunction. Antioxidants can be described as a system that protects biomolecules and the organism against the harmful effects of free radicals, reduces or repairs the damage done by reactive oxygen species (ROS) to the target molecule, and this is called antioxidant defense. It is known that the mechanisms caused by the increase in ROS resulting from oxidative stress are positively related to the pathology of many diseases such as cancer, metabolic syndrome, atherosclerosis, malaria, Alzheimer’s disease, rheumatoid arthritis, neurodegenerative diseases and preeclampsia.
Increased hemolysis rate in plasma tubes after implementation of a fully automated sample delivery and acceptance system
Authors: Saenger Jonathan A. , Atamaniuk Johanna , Gaggl Martina , Asenbaum Johannes , Huber Florian A. , Grieb Alexander , Födinger Manuela 
Published: February 2023

Abstract

Objectives
Automated sample delivery and laboratory acceptance systems (PTAS) may influence the hemolysis rate of blood samples due to g-forces, abrupt acceleration, and rapid deceleration. However, quantitative data regarding the rate of hemolysis in PTAS is limited. To fill this void, the effect of a pneumatic tube in combination with an acceptance system (PTAS) on the hemolysis rate was investigated in this study.

Methods
Lithium heparin plasma tubes were transported from different clinical departments to the hospital’s laboratory (a) by employees or (b) with an automated PTAS and analyzed for the presence of hemolysis based on a hemolysis index (HI) of >25. Hemolysis indices of 68.513 samples were retrieved from the laboratory information system before and after installation of the PTAS and were subjected to statistical analysis.

Results
A total of 32.614 samples were transported by employees, of which 3.815 samples (11.70%) were hemolytic, and 9.441 out of 35.899 samples delivered by PTAS (26.30%) were hemolytic. After the implementation of the PTAS, hemolysis rates increased in all departments.

Conclusions
Automated PTAS are associated with increased hemolysis rates. This has implications for routine patient management and should be considered for the transportation of samples used for the determination of hemolysis-sensitive laboratory parameters.
From Sprachtheorie to semantics and cybernetics: Karl Bühler’s “Pocketbook on practical semantics”
Authors: McElvenny James , Knobloch Clemens 
Published: February 2023

Abstract
Among the many Central European scholars and intellectuals driven into exile across the Atlantic in the 1930s was the prominent Vienna psychologist Karl Bühler (1879–1963). Bühler had great difficulty establishing himself in his new home of the United States, despite his attempts to adapt his ideas to the American scene. In this paper, we look at one such attempt at adaptation, the unpublished manuscript of Bühler’s “Pocketbook on Practical Semantics,” an effort to turn the Sprachtheorie of his Vienna period into a contribution to the applied semiotics and communications research popular in America at the time. Our paper represents the first detailed examination of the “Pocketbook” manuscript that places it in its context in the history of semiotics.
Comparison of Mechanical Properties Obtained for Armor Steels: Conventional Methods vs. Nanoindentation
Authors: Ekmekci Dursun , Cora Ömer Necati 
Published: February 2023

Abstract
The mechanical properties of three armor steels, namely Ramor 500, Ramor 550, and Armox Advance, were acquired by nanoindentation and conventional methods, and then the results were compared. To this goal, samples were extracted from different (e.g., undeformed and deformed) zones of the ballistically tested armor plates. Then, nanoindentations were performed at 10-mN maximum load and different maximum indentation depths (50–150 nm). In addition to the hardness and modulus of elasticity values of the examined materials, residual stress values of the samples were calculated through the equations suggested in the literature. These values were then compared with the residual stress measurements obtained with the conventional x-ray diffraction (XRD) - sin2ψ method. Moreover, Charpy V-notch impact tests were performed to calculate the fracture toughness of armor steel samples. Microstructural analysis (e.g., optical microscope, scanning electron microscope, atomic force microscope), surface roughness, and micro-hardness (micro-Vickers) measurements were also obtained. It was noted that hardness values for the Ramor 500 and Ramor 550 armor steels were in the range of 5.5–9 GPa, whereas the hardness values of Armox Advance samples were obtained in the 8.6–10.2 GPa range at a 50-nm indentation depth. The residual stress values obtained with nanoindentation were found to be in quite good agreement with the one obtained through XRD. It was proven that nanoindentation can be used to acquire several mechanical properties through considerably less sample preparation procedure, in an automated, and a more representative manner because of the measurements obtained at multiple points.
Secure and efficient implementation of facial emotion detection for smart patient monitoring system
Authors: Zaman Kh Shahriya , Reaz Md Mamun Bin Ibne 
Published: February 2023

BackgroundMachine learning has enabled the automatic detection of facial expressions, which is particularly beneficial in smart monitoring and understanding the mental state of medical and psychological patients. Most algorithms that attain high emotion classification accuracy require extensive computational resources, which either require bulky and inefficient devices or require the sensor data to be processed on cloud servers. However, there is always the risk of privacy invasion, data misuse, and data manipulation when the raw images are transferred to cloud servers for processing facical emotion recognition (FER) data. One possible solution to this problem is to minimize the movement of such private data.MethodsIn this research, we propose an efficient implementation of a convolutional neural network (CNN) based algorithm for on‐device FER on a low‐power field programmable gate array (FPGA) platform. This is done by encoding the CNN weights to approximated signed digits, which reduces the number of partial sums to be computed for multiply‐accumulate (MAC) operations. This is advantageous for portable devices that lack full‐fledged resource‐intensive multipliers.ResultsWe applied our approximation method on MobileNet‐v2 and ResNet18 models, which were pretrained with the FER2013 dataset. Our implementations and simulations reduce the FPGA resource requirement by at least 22% compared to models with integer weight, with negligible loss in classification accuracy.ConclusionsThe outcome of this research will help in the development of secure and low‐power systems for FER and other biomedical applications. The approximation methods used in this research can also be extended to other image‐based biomedical research fields.
Language variation in minority online newspapers: The example of the “Deutsche Allgemeine Zeitung” in Kazakhstan
Authors: Földes Csaba 
Published: February 2023

This article discusses the online edition of the “Deutsche Allgemeine Zeitung” (DAZ, German General Newspaper), an exceptional media product in Kazakhstan. This medium was chosen mainly for its very complex linguistic and cultural configuration. The linguistic forms are German, while the discourse and text traditions suggest a Russian influence due to the long hegemony of Russian as the language of culture and education in Kazakhstan. Additionally, the current sociocultural frame of reference is of genuine Kazakh origin.The central aim of this evidence-based media linguistic analysis was to describe the unique features in the language of this online medium, i.e. the multilingual aspects of language variation and aspects related to language and cultural contact.The methodology is based on a linguistic concept of saliency and used interrater reliability in the linguistic assessment. The study showed that the online version and the print version differ not only on a technical level, but also in their journalistic and linguistic design. The digital version is marked by livelier, more idiomatic, and more colorful texts than the print version. These differences can likely not just be attributed to the greater range of options provided by the new medium, but possibly also to the larger share of contributions by authors from Germany in the online version compared to the print version. In the written practices examined in this article it could be shown that authors from Kazakhstan generally used ‘multiliteracy’ form that also generated emergent forms.
Impact of adding bismuth vanadate (BiVO4) nanoparticles on the electrical and mechanical properties of Cu0.5Tl0.5Ba2Ca2Cu3O10-δ ceramic
Authors: Rekaby M. , Matar M. 
Published: February 2023

AbstractA mechanochemical route was used to prepare bismuth vanadate (BiVO4) with an average grain size of 20 nm. To obtain (BiVO4)x/Cu0.5Tl0.5Ba2Ca2Cu3O10-δ composites, appropriate amounts of BiVO4 (x) were added to Cu0.5Tl0.5Ba2Ca2Cu3O10-δ via a solid-state reaction. The superconducting critical temperature (Tc) was dropped from 119.5 to 103.5 K with x. The different conduction mechanisms were studied using the Aslamazov–Larkin and Lawrence–Doniach models. Four different fluctuation zones were observed. As the BiVO4 content rose the coherence length was increased from 19.69 to 39.30 Å. Superconducting parameters such as thermodynamic critical field Bc(0), lower critical magnetic field Bc1(0), upper critical magnetic field Bc2(0), and critical current density Jc(0) were decreased with x. Furthermore, the mechanical strength was studied through Vickers microindentation test and variety of mechanical parameters, including elastic modulus (E), yield strength (Y), fracture toughness (K), and brittleness index (B), were determined as a function of BiVO4 content.

Graphical abstract
Pre-Pregnancy eGFR and the Risk of Adverse Maternal and Fetal Outcomes: A Population-Based Study
Authors: Tangren Jessica , Bathini Lavanya , Jeyakumar Nivethika , Dixon Stephanie N. , Ray Joel , Wald Ron , Harel Ziv , Akbari Ayub , Mathew Anna , Huang Susan , Garg Amit X. , Hladunewich Michelle A. 
Published: February 2023

Significance Statement
Pregnancies in women with CKD carry greater risk than pregnancies in the general population. The small number of women in prior studies has limited estimates of this risk, especially among those with advanced CKD. We report the results of a population-based cohort study in Ontario, Canada, that assessed more than 500,000 pregnancies, including 600 with a baseline eGFR < 60 ml/min per 1.73 m2. The investigation demonstrates increases in risk of different adverse maternal and fetal outcomes with lower eGFR and further risk elevation with baseline proteinuria.

Background
CKD is a risk factor for pregnancy complications, but estimates for adverse outcomes come largely from single-center studies with few women with moderate or advanced stage CKD.

Methods
To investigate the association between maternal baseline eGFR and risk of adverse pregnancy outcomes, we conducted a retrospective, population-based cohort study of women (not on dialysis or having had a kidney transplant) in Ontario, Canada, who delivered between 2007 and 2019. The study included 565,907 pregnancies among 462,053 women. Administrative health databases captured hospital births, outpatient laboratory testing, and pregnancy complications. We analyzed pregnancies with serum creatinine measured within 2 years of conception up to 30 days after conception and assessed the impact of urine protein where available.

Results
The risk of major maternal morbidity, preterm delivery, and low birthweight increased monotonically across declining eGFR categories, with risk increase most notable as eGFR dropped below 60 ml/min per 1.73 m2. A total of 56 (40%) of the 133 pregnancies with an eGFR <45 ml/min per 1.73 m2 resulted in delivery under 37 weeks, compared with 10% of pregnancies when eGFR exceeded 90 ml/min per 1.73 m2. Greater proteinuria significantly increased risk within each eGFR category. Maternal and neonatal deaths were rare regardless of baseline eGFR (<0.3% of all pregnancies). Only 7% of women with an eGFR <45 ml/min per 1.73 m2 received dialysis during or immediately after pregnancy.

Conclusions
We observed higher rates of adverse pregnancy outcomes in women with low eGFR with concurrent proteinuria. These results can help inform health care policy, preconception counseling, and pregnancy follow-up in women with CKD.
Pessoas em situação de rua: inclusão/exclusão social, políticas públicas, atuação do psicólogo
Authors: Collodel Magalhães Reis Tomás , Valério dos Santos Azevêdo Adriano 
Published: February 2023

Pessoas em situação de rua estão diariamente expostas às situações de vulnerabilidades e preconceitos, o que mostra a necessidade de reconhecimento de seus direitos previstos nas legislações Brasileiras. Este texto objetivou discutir os aspectos conceituais do processo de inclusão/exclusão social de pessoas em situação de rua relacionando-os com as políticas públicas e ações da Psicologia. O estudo analisou o aspecto teórico, a cronologia referente a construção e implementação de políticas públicas, e atuação do psicólogo. Inicialmente apresenta-se um modelo teórico que considera a perspectiva dialógica da inclusão/exclusão social. Verificou-se que no Brasil, na década de 1990, as legislações direcionadas para a assistência social impulsionaram, no ano de 2009, a construção de uma política pública para pessoas em situação de rua. Isto possibilitou o surgimento de serviços socioassistenciais, por exemplo, o Centro de Referência Especializado para População em Situação de Rua (Centro Pop), e Consultório nas Ruas. É nesse contexto que o psicólogo desenvolve práticas baseadas em conhecimentos propostos pelas legislações vigentes e recomendações do Conselho Federal de Psicologia priorizando o diagnóstico socioterritorial, a escuta qualificada e a redução de danos buscando valorizar as singularidades. Existem limites e desafios referentes a reconstrução de vínculos familiares, reinserção social e construção de projetos e perspectivas de vida. Recomenda-se delimitar intervenções psicossociais articuladas com políticas públicas para promover a garantia dos direitos humanos, cidadania, e justiça social.
Vitamin D deficiency in persons over 50 years of age with and without carotid artery atherosclerosis: a cross-sectional outpatient study
Authors: Mikhailova L. V. , Kovalenko M. A. , Litvinova L. S. , Gazatova N. D. , Vulf M. A. 
Published: February 2023

Highlights. The association between vitamin D levels and estimated glomerular filtration rate and triglyceride levels was revealed in people with cardiovascular risk factors aged older than 50 years. Vitamin D deficiency was more frequently noted in patients with acute coronary syndrome. They also were more likely to have abdominal obesity and type 2 diabetes mellitus, indicating the association between vitamin D deficiency and metabolic syndrome. The high prevalence of both vitamin D deficiency and metabolic syndrome in the population necessitates further larger-scale studies to identify the relationship between vitamin D levels and cardiovascular risk factors.Aim. To assess the level of vitamin D in people older than 50 years with the presence/ absence of carotid artery atherosclerosis.Methods. The single-stage observational study was conducted, the study included 70 outpatients over 50 years of age, of which 17 (24%) were men and 53 (76%) were women. The mean age of the patients was 66 (60; 72) years. All examined patients underwent history taking, anthropometry, biochemical examination of blood plasma with the determination of lipid spectrum, glucose, creatinine and estimated glomerular filtration rate, echocardiographic examination. The presence of carotid atherosclerosis was determined by ultrasound examination of the carotid arteries. The study of the level of 25-OH vitamin D in blood serum was carried out by enzyme immunoassay (25-OH vitamin D ELISA).Results. It was found that about half (46%) of the examined persons have insufficient levels of vitamin D in the blood plasma, while its deficiency (less than 20 ng/mL) was determined in 9% of patients. Individuals with carotid atherosclerosis had slightly lower levels of vitamin D than those without it, but the differences did not reach statistical significance. In acute coronary syndrome survivors, there was a statistically significant decrease in vitamin D levels, the vast majority of these patients had diabetes mellitus and abdominal obesity. Statistically significant moderate relationships were found between vitamin D levels and triglyceride levels (r = –0.33; p<0.05) and estimated glomerular filtration rate (r = 0.26; p<0.05), which confirms the association of vitamin D deficiency with metabolic syndrome. No statistical regularity was found between the level of vitamin D and other laboratory biochemical parameters, as well as morphological changes in the heart and blood vessels.Conclusion. Insufficient content of vitamin D in blood plasma is more common in individuals with a history of acute coronary syndrome, among them diabetes mellitus and abdominal obesity are more often detected, which confirms the relationship of vitamin D deficiency with metabolic syndrome.
Possibilities of a portable electrocardiogram and pulse wave recorder in detecting left ventricular systolic dysfunction
Authors: Sagirova Zh. N. , Kuznetsova N. O. , Gubina A. Yu. , Dhif I. , Mishakina N. Yu. , Kaloshina I. V. , Gognieva D. G. , Chomakhidze P. Sh. , Kopylov F. Yu. 
Published: February 2023

Highlights. The article presents a novel and unique method for assessment of left ventricular systolic disfunction using electrocardiography and photoplethysmography data. This method will improve and simplify the detection of cardiovascular diseases.Aim. To evaluate left ventricular (LV) systolic function using electrocardiogram (ECG) and photoplethysmogram (PPG) signals recorded by a single-channel ECG and PPG-based monitor.Methods. The prospective study included 489 patients over 18 years old with various cardiovascular diseases. All participants underwent echocardiography to determine the main indicators of LV systolic function: LV ejection fraction (EF), LV outflow tract velocity time integral (LVOT VTI), and global longitudinal strain (GLS). Moreover, all patients underwent 1-lead ECG and PPG recording using a single-channel ECG and PPG-based monitor (CardioQvark). The obtained data were analyzed, and ROC curve analysis was performed.Results. We have identified ECG and PPG parameters associated with a decrease in LV contractile function. During the analysis, the ECG, T-wave amplitude (TA) and RonsF parameters showed the highest diagnostic accuracy. With EF below 55%, the area under the ROC curve (AUC) was 0.822, sensitivity (Se) 80%, specificity (Sp) 69% in EF below 55% in TA; in RonsF AUC was 0.743, Se 81%, Sp 77%. With EF below 40%, AUC was 0.915, Se 85%, Sp 83% in TA, and in RonsF AUC was 0.844, Se 82%, Sp 82%. Diagnostic accuracy of ECG signals in case of LVOT VTI lower than 16 cm was measured: TA (AUC 0.755, Se 82%, Sp 70%), RonsF (AUC 0.620, Se 77%, Sp 72%). PPG signals were not significantly associated with reduced EF; however, the pulse wave parameters were associated with lower LVOT VTI: in DP-B0 AUC was 0.687, Se 71%, Sp 74%. The combination of ECG and PPG signals was significantly associated with EF below 40% (RonsF * DP-SEP (AUC 0.877, Se 86%, Sp 85%). ECG and PPG signals were not associated with LV GLS.Conclusion. Assessment of LV systolic function can be performed by analyzing ECG and PPG signals recorded using a portable single-channel CardioQvark monitor.
ANTAGONISTIC ACTIVITY OF LACTOBACILLI PROBIOTIC STRAINS IN CO-CULTIVATION
Authors: Strashnova I. V. , Yamborko G. V. , Vasylieva N. Yu. 
Published: February 2023

SummaryAim. To investigate the antagonistic properties of multistrain compositions and consortia created on the basis of probiotic strains of bacteria of the genus Lactobacillus.
Methods. A biocompatibility was investigated by co-cultivation of lactobacilli strains on MRS-agar medium. To create the compositions used separately grown daily broth cultures in certain proportions, to create consortia - strains of lactobacilli in the appropriate proportions were cultivated together in MRS broth during 24 h. The antagonistic activity of the created combinations against 10 test cultures was determined by the well-diffusion method.
Results. According to the results of biocompatibility studies, strains of Lactobacillus spp. 175, M2 and M3 were selected. These strains were basis for creation 7 compositions and 7 consortia with certain ratios of broth cultures of these strains. Lactobacilli in the compositions show slightly better antimicrobial properties compared to consortia. The composition of Lactobacillus sp. M2 + Lactobacillus sp. M3 + Lactobacillus sp. 175 in a ratio of 1: 2: 2 showed the best antagonistic activity against all test strains of microorganisms.
Conclusions. Created on the basis of probiotic strains of Lactobacillus spp. 175, M2 and M3 compositions and consortia are strong antagonists of different test cultures. Manifestation of activity depends on the method of combining strains in combination, the best effect is achieved by growing each strain separately with subsequent mixing of broth cultures. The most antagonistically active is a composition based on broth cultures of Lactobacillus sp. M2 + Lactobacillus sp. M3 + Lactobacillus sp. 175 in a ratio of 1: 2: 2.
Common Peroneal Nerve Injury Due to an All-Inside Repair of the Posterior Horn of Lateral Meniscus
Authors: Koiwa Kai , Oshiba Hiroyuki , Yamazaki Hiroshi 
Published: February 2023

Case:
An 18-year-old man sustained a peroneal nerve (PN) injury during an all-inside repair of the posterior horn of the lateral meniscus from the medial portal. Although he could dorsiflex his ankle actively after emergence from general anesthesia, he had a foot drop on the day after surgery. Exploration of the PN at 5 months postoperatively revealed that the nerve was entrapped by the suture. Fifteen months after a nerve repair using a sural nerve graft, he recovered from the foot drop.

Conclusion:
This case report highlights the risk of PN injury during an all-inside repair of the posterior horn of the lateral meniscus.
Deformity-Correcting Ankle Fusions With Patient-Specific 3D Operative Planning and 3D-Printed Cut Guides
Authors: Bouchard Maryse , Da Costa Sophia , Peel Brandon 
Published: February 2023

Case:
We report 2 cases of severe arthrogrypotic clubfeet presenting with multiplanar ankle deformities. Two patients (3 ankles) were treated with deformity-correcting ankle fusions using 3D preoperative planning and 3D-printed patient-specific cut guides. This technique enabled safe, accurate, and efficient surgical correction with good clinical outcomes. At 1 year, physical function and patient outcome measures improved.

Conclusion:
In the setting of complex multiplanar deformities of the foot and ankle, the use of 3D preoperative planning and 3D-printed cut guides is a safe and accurate adjunct to ankle fusion.