bluuebunny/crossref_metadata_2025_split huggingface dataset:
Closing the Gap Between Static and Dynamic User Equilibrium in Traffic Assignment: A Multiple Cities Study
Authors: Li Danqing , Yan Long , Hu Luzhe , Li Yixuan , Hu Bowen , Li Chunxiao , Song Yulun , Xu Yanyan 
Published: January 2023

Abstract
Static user equilibrium model and dynamic user equilibrium model are two commonly used traffic assignment models. Compared to dynamic model, static model costs much less time, needs less information but cannot assign the traffic in time dimension so it cannot obtain the time series of traffic flow. We can divide the time interval into segments and apply static model on each segment, so that the time series of traffic flow can be obtained. A challenge of this method is how to determine the scale of the time segment so that the result of static model can be close to dynamic model. This paper proposes a big data-driven analysis framework and uses China’s 40 cities’ road networks and traffic flow data as samples. We calculate the gap between the results of dynamic and static models using different scales of time segment. It is shown that the unevenness of the distribution of travel demand in time dimension and other indexes which measure the volume of the city, such as GDP, have a strong correlation with the optimal scale of time segment for static model.
Reduced precision of motor and perceptual rhythmic timing in autistic adults
Authors: Cannon Jonathan , Cardinaux Annie , Bungert Lindsay , Li Cindy , Sinha Pawan 
Published: January 2023

Abstract

Recent results suggest that autistic individuals find it challenging to temporally coordinate their actions with predictable external cues, as indicated, for instance, by lower accuracy in synchronizing finger taps to an auditory metronome compared with their non-autistic peers. However, it is not yet clear whether these difficulties are driven primarily by motor or perceptual impairments. We recruited autistic and non-autistic participants for an online study which tested both finger tapping synchronization and continuation as well as purely perceptual (non-motoric) rhythmic timing. We fractionated each participant’s synchronization results into several individual-specific parameters representing error correction, motor noise, and internal time-keeper noise, and also investigated error-correcting responses to small timing perturbations in metronome timing. Contrary to previous work, we did not find strong evidence for reduced tapping error correction. However, we found compelling evidence for noisier internal rhythmic time-keeping in the synchronization, continuation, and perceptual components of the experiment. These results suggest that noisier rhythmic timing processes underlie some sensorimotor coordination challenges in autism.
Development of Design for Alternative Fuel
Authors: Altuwair Ibrahim 
Published: January 2023

Abstract
The research attempts to overcome defined gap by taking the following steps: The primary contribution of the study is to upgrade alternative measures for transportation preparation design. Increasing competency and enhancing safety in alternatives such as, Compressed Natural Gas CNGV, Hydrogen HV, and Electrical Vehicles EV. In this research, the adopted acceptance index and end-users behaviors’ towards alternatives CNGV is developed; the vital goal of the study is to establish a risk-based index to support the design of alternatives. The research defines individually the study tool which is considered as varied from one to another, unlike artificial tools or devices. It helps to understand the mechanism of the individual behavior process and decision making; an experimental study is designed. Empirical method is applied to validate the adopted process. This research utilized practical methodological approaches to approve the research procedures. The first findings discussed are the descriptive statistics. Descriptive statistics were calculated for all constructs. The research demonstrated by formulating a relationship between proposed variables and industry.
Proton Pump Inhibitors Reduce Survival Outcomes in Patients Treated with Capecitabine: Meta-analysis
Authors: Mohyeldeen Dina , Arafat Waleed 
Published: January 2023

Abstract
Background
Proton pump inhibitors (PPIs) are widely-used over-the-counter drugs. However, possible, and quite ambiguous, interaction has been suggested between capecitabine and PPIs; with some discrepancy still being present within the literature regarding the possible risks, or even benefits, of their concomitant use. This meta-analysis therefore aims to analyze data from the literature regarding both the risk of PPIs on survival in patients treated with capecitabine, as well as their benefit regarding the incidence of hand foot syndrome (HFS).
Methods
A total of 17 studies were included after searching Pubmed, Medline, and Cochrane until October 2022 for the effect of PPIs on the treatment efficacy and pharmacokinetics, and incidence of HFS. Revman Ver. 5.3 was used for all statistical analyses.
Results
Our data showed a significant HFS reduction at a relative risk of 0.77 (95% CI: 0.70–085; p < 0.00001) in the PPI-using groups compared to control. Meta-analysis of studies assessing survival; however, showed reduction in almost all survival aspects, most notably within the recurrence-free survival, with a hazard ratio of 1.75; 95% CI: 1.21–2.53; p = 0.003.
Conclusion
Individual data incriminating the use of PPIs with capecitabine is quite limited; however, our robust survival data on around 30,000 patients gave significant worse survival outcomes, particularly in the (neo)adjuvant setting.
Pan-cancer analysis to provide a reliable basis for the clinical use of TIM-3 immunosuppressants
Authors: Mo Bangqian , Wang Yongfeng , Liu Deming , Cai Hui 
Published: January 2023

Abstract
Background
TIM-3 belongs to the immunoglobulin superfamily and is currently one of the most valuable immunosuppressants. HAVCR2 is the gene that codes for TIM-3, and its expression has been linked to the clinical efficacy of TIM-3 immunosuppressants. The study aims to provide potential guidance for the use of TIM-3 immunosuppressants in pan-cancer.
Methods
Data related to HAVCR2 in pan-cancer was obtained from multiple databases. First, differences in HAVCR2 expression between pan-cancerous and corresponding normal tissues were analyzed, and Survival rates were analyzed using Kaplan-Meier and Cox analyses. Besides,the correlation between HAVCR2 expression and DNA methyltransferases (DNMTs), tumor-infiltrating immune cells(TIICs), tumor mutational burden(TMB), microsatellite instability (MSI), mismatch repair (MMR), and immune checkpoint (ICP) was investigated by Spearman correlation analysis.Functional enrichment analysis of HAVCR2 was also performed to explore its biological and molecular roles in tumors. Finally, validation of HAVCR2 expression was performed in some cancer cell lines to analyze its differential expression.
Results
Our comprehensive pan-cancer analysis showed that HAVCR2 expression was significantly upregulated in most malignancies and correlated with poor prognosis. Secondly, there was a significant association between HAVCR2 methylation levels and survival prognosis in patients with multiple tumors, while patients with HAVCR2 mutated tumours showed a good prognosis. Moeeover, the expression of HAVCR2 was strongly associated with excessive infiltration of immune cells in the tumour microenvironment(TME). In addition, the expression of HAVCR2 significantly correlated with TMB, MSI, MMR, and ICP in different types of tumors, and the correlation results correlated with the efficacy of TIM-3 immunosuppressants in some cancer patients. More importantly,functional enrichment analysis based on HAVCR2 indicates that HAVCR2 acts primarily through the regulation of immunobiological processes in the TME.RT-PCR validated HAVCR2 expression in multiple cancer cell lines, consistent with the bioinformatic analysis results.
Conclusions
The expression of HAVCR2 is significantly correlated with heterogeneous features of pan-cancer, and the results of this correlation have potential value in guiding the clinical application of TIM-3 in pan-cancer spectrum.
Spatial Analysis and Health Risk Assessment of Pollutants in the Ground Water of District Narowal, Punjab, Pakistan
Authors: Luqman Muhammad Hamid 
Published: January 2023

Abstract
Because of the importance of water in maintaining life and socio-economic development, drinking water quality of District Narowal, Punjab, Pakistan has been assessed using spatial techniques like IDW and Kriging, WQI approach, Non-Carcinogenic and Carcinogenic Health Risk Assessment. Water quality was assessed for the time period between 2014–18, using 17 different physicochemical parameters from 1743 sites each, from two time periods 2014–16 and 2016–18 respectively. The drinking water of Narowal was categorized into 5 different classes on the basis of WQI i.e., Excellent, good, poor, very poor and not suitable for drinking. WQI Values of 210.1537 and 267.75 was observed during 2014–16 and 2016–18 showed very poor quality of drinking water during 2014–18. 28.5% of the study area during time period 2014–16 and 36.1% during time period 2016–18 showed substandard drinking quality. 3.3% of the study area during 2014–16 and 7.9% during 2016–18 showed health risks related to chloride for adults while 0.1% of study area during 2014–16 and 11.1% during 2016–18 showed health risks related to nitrite in adults. Results indicated that due to the human intervention the quality of the drinking water and risks related to drinking sub-standard water of District Narowal become getting worse in a very fast rate, so water should be drink after suitable treatment. These risks can also be eliminated by decreasing the use of chemical and synthetic fertilizers and pesticides for agriculture.
Lateral detachment forces of Bacillus niabensis and Alteromonas litorea against antifouling paint additive
Authors: Al-Amin Murni Noor , Dagang Wan Rosmiza Zana Wan , Malek Nik Ahmad Nizam Nik , Jamaluddin Haryati 
Published: January 2023

Abstract
Objective Bacterial adhesion on various marine biotic or abiotic surfaces and subsequent biofilm formation paves the path of biofouling in marine environment. The aim of the present investigation was to determine the lateral detachment forces between the the coated antifouling paint additive and local isolated marine bacteria; Bacillus niabensis and Alteromonas litorea using atomic force microscopy (AFM).
Methods A paint additive was prepared by employing the active compounds, silver ion (Ag+) and surfactant hexadecyltrimethylammonium (HDTMA) embedded in the kaolinite clay structure. An incubated 100 µL bacterial suspension loaded onto the coated antifouling paint additive were scanned using AFM with the scan rate of 40 µm/s and scan size of 10 × 10 µm2. Lateral detachment force was measured from a lower set point value of 0.3V to a maximum set point 10.0V.
Results A weak interaction was observed between the model bacteria and paint additive (Or-Ag-Kao) coated surface with the mean lateral detachment force of 139.4 nN (B. niabensis) and 146.2 nN (A. litorea). Major contact surface area reduction observed on paint additive (Or-Ag-Kao) coated surfaces with 0.275 µm2 for B. niabensis and 0.391 µm2 for A. litorea indicated that paint additive coating successfully minimized bacterial attachment on the surface.
Conclusion The antifouling paint additive shows a reduction in lateral forces and minimized its surface contact, which could further prevent the microfouling formation on marine structures.
Enhanced strength, toughness, and reliability in crab exoskeleton inspired additively manufactured porous thermoplastics
Authors: Keles Ozgur , Karakoc Alp , Wu Cheng-Lun , Anderson Eric H. 
Published: January 2023

Abstract
Inspired by crab exoskeleton, fused deposition modeling (FDM) was used to control local deposition of acrylonitrile‐butadiene‐styrene (ABS) polymer and local porosity. Effects of four different meso-scale structures on the stochastic mechanical properties were investigated. Tensile tests showed that the biomimetic Bouligand structure increases strength, strain at break, toughness, and mechanical reliability of additively manufactured porous ABS. Change in meso-scale structures impacted variations in mechanical properties. Weibull moduli--as an indication of variation in properties--ranged from 17 to 54 for fracture strength. Variations in strain at break were higher compared to strength with a Weibull modulus between 6 and 16. Finite element simulations captured the experimental fracture behavior of porous structures. Simulations revealed significant damage accumulation in porous Bouligand structures.
Protected Area Network Contributions to Landscape Connectivity under Global Change
Authors: Mozelewski Tina G. , Scheller Robert M. 
Published: January 2023

AbstractContext Both anthropogenic change and environmental variability cause spatiotemporal fluctuations in the availability of habitat on a landscape. Land acquisition and restoration for conservation also facilitates dynamic habitat accessibility. Accounting for these spatiotemporal dynamics is critical to the success of conservation planning to increase landscape connectivity. Objectives We aimed to forecast the individual and interactive effects of anthropogenic change, environmental variability, and conservation action on landscape connectivity over time. In doing so, we sought to evaluate the capacity of conservation actions intended to enhance connectivity to keep pace with global change. Methods We used a landscape change model to simulate strategies for the expansion of protected area networks on a ~1.5 million ha landscape in North Carolina. We forecasted spatiotemporal changes (2020-2100) to complex habitat networks across multiple scenarios of climate and land-use change, using graph theory to assess the variance in connectivity between conservation strategies and among global change futures. Results Both climate and land-use change reduced the influence of conservation on landscape connectivity, but through different mechanisms. Climate change increased available longleaf pine habitat, improving overall landscape connectivity and camouflaging connectivity improvements from conservation. Land-use change reduced the connectivity improvements facilitated by conservation as the cost of movement between habitat patches increased. Conclusion Rather than acting synergistically with land-use change, climate change negated the connectivity declines from land-use change in the study area. More broadly, our approach to forecast landscape-level responses to climate change, land-use change, and management can support the identification of conservation strategies that are more robust to global change, better enhancing landscape connectivity.
Dual Graph Neural Network for Overlapping Community Detection
Authors: Li Xiaohong , Peng Qixuan , Li Ruihong , Ma Huifang 
Published: January 2023

Abstract
Community detection has long been designed to find communities with different structures in various networks. It is now widely believed that these communities often overlap each other. However, due to the complexity and diversity of the network, it is often difficult to accurately identify the overlapping community structure in many real networks. Considering the above problem, we introduce a dual graph neural network for overlapping community detection (DGOCD) under the framework of the extended Bernoulli-Poisson (EBP). First, we build two graphs to model information of different orders between nodes respectively, and use a set of GCNs as a backbone to learn semantic representations of the above graphs in parallel. Then we introduce the concept of topological potential matrix to aggregate the embedding representations of the two channel graphs. Moreover, for learning the affiliations between nodes and communities, we carry out network reconstruction based on the former information. Finally, the reconstructed network is sent into the GCN to get the final community division. Experimental results on real network datasets demonstrate that the proposed DGOCD consistently outperforms existing methods.
Land use / land cover change detection and forecasting using GEE and hybrid Markov-CA model in the Nainital, a district of Uttarakhand State, India
Authors: Pokhariya Hemant Singh , Singh D P , Prakash Rishi 
Published: January 2023

Abstract
Analysing and predicting changes in land use/ land cover (LU/LC) is a very essential study for decision makers to manage and control environmental sustainability by assessing the effects of global climate change. This study, aims to evaluate LULC changes in the last two decades from 2000 to 2020, as well as, to predict land cover changes in 2030 using Google Earth Engine and IDRISI software. Random Forest classification scheme in GEE is used for classifying land covers. Based upon 2000 and 2010 classified maps, the “transition probability” matrix is determined by using IDRISI SILVA 17.0 software. The Markov-CA integrated method in IDRISI is used to predict 2020 LULC pattern and it is validated by actual LU/LC classified map of 2020 with a kappa index of 0.93. Finally, the LU/LC map of 2030 is predicted to analyse land cover changes for controlling and monitoring environment sustainability. Based on the results of the current analysis, Nainital, a district of Uttarakhand State, India has undergone a significant increase in urban area and agricultural area particularly in west and south direction(plain region of study area), whereas there is a sharp decrease in forest and waterbody area. In this aspect, Remote sensing (RS) methods and geographic information systems (GIS) are crucial tools that can be utilised to identify the driving elements linked with the surrounding environment that lead to altering climate and biodiversity loss.
Effect of Overnight Orthokeratology Lens Wear on Sleep and Quality of Life in Children Aged 8-12 Years and Relationship Between Corneal Morphology and Visual Function
Authors: Huali Hong , Yijiao Long , Lihong Li , Yaiyan Lu , Weien Lin 
Published: January 2023

Abstract
It was to investigate vision, sleep, quality of life (QOL), and corneal morphology changes before and after overnight orthokeratology lens wear in myopic children aged 8–12 years. 100 myopic children were randomly divided into control group and test group, and glasses and overnight orthokeratology lens wear were worn separately. Uncorrected visual acuity, refraction, axial length, corneal endothelial cells, and corneal morphology were compared beforewear (0d), and 1 month (1mo), 3 months (3mo), and 6 months (6mo) after wear. The OQASTM II was used to evaluate visual quality, the Pittsburgh sleep quality index (PSQI) was used to evaluate sleep quality, and the QOL scale was used. Compared with 0d, there were significant differences in uncorrected visual acuity, refraction, axial length, corneal cell morphology, corneal morphology, visual quality, PSQI score, and QOL score between the control group and the test group (P < 0.05). Compared with the control group, in the test group, the uncorrected visual acuity, refraction, corneal cell variation coefficient, and QOL score at 3mo and 6mo after wear increased (P < 0.05); axial length, corneal endothelial cell density, hexagonal cell ratio, sleep onset time, sleep disorders, daytime function, PSQI, and OQAS values decreased (P < 0.05); subjective sleep quality, sleep duration, and sleep aids increased at 1mo after wear (P < 0.05). Myopic children with overnight orthokeratology lens wear can improve vision, life and sleep quality, but subjective sleep quality is reduced at early wear.
Wind conversion systems effects on power grid and ability of TCSC and SSSC devices for dynamic performance enhancing
Authors: Yahia Saoudi , Rachdi Taha , Ayachi Errachdi 
Published: January 2023

Abstract
In this paper, two wind power farms are proposed to produce the active power using two variable profiles of the wind. Indeed, in order to ensure the proper functioning of the electrical power system, two FACTS devices are installed in series between buses 1 and 3, separately. The effects of disturbances, in the form of variable profiles of the wind, affecting the voltages and frequencies in the IEEE 14-bus system are studied. After simulation, good results are obtained in terms of the overall stability of the electrical energy system. The found results prove, both, the voltage errors in each bus, and, the losses in each line by installing of the FACTS. In addition, the harmonics created by the wind disturbances are limited.
Two-Dimensional Lock-in Amplifier Algorithm in Spatial Domain
Authors: Zhang Meng 
Published: January 2023

Abstract
An algorithm based on a two-dimensional lock-in amplifier method has been proposed for extracting complex plane components in images. Traditional one-dimensional time-frequency lock-in amplifier estimates the amplitude and phase of a periodic signal at a frequency determined by a reference signal that may be submerged by noise. In the field of digital image processing, it is necessary to analyze the information in the spatial domain. In this paper, a mathematical model has been established to describe the complex plane component in the image, and a two-dimensional lock-in amplifier algorithm has been developed. Compared with traditional lock-in amplifier algorithms, the proposed algorithm can be used to process signals with higher dimensions. Simulation and experimental results show that the proposed algorithm can effectively extract the complex plane components polluted by noise at given frequencies. This two-dimensional lock-in amplifier algorithm can be applied to the extraction and reconstruction of fringe patterns in images submerged by noise. The limitation of the proposed algorithm has been discussed.
Multi-step methods’ ability on the existence of solutions of multi-term fractional q−differential equations with arbitrary fractional order
Authors: Samei Mohammad Esmael , Zanganeh Hasti , Houas Mohamed , Ram Bhagwat 
Published: January 2023

Abstract
This paper thinks about a nonlinear multi term q–differential conditions of arbitrary fractional orders. New existence and uniqueness comes about are built up utilizing Ba-nach contraction principle. Other existence results are gotten utilizing Schaefer and Krasnoselskii fixed point theorems. In organize to clarify our comes almost, some illustrative cases are in addition displayed.
(2010) Mathematics Subject Classifications: 34A08, 34B16, 39A13.