bluuebunny/crossref_metadata_2025_split huggingface dataset:
PROTECTIVE ROLE OF ANKAFERD BLOOD STOPPER ON CADMIUM-INDUCED ACUTE NEPHROTOXICITY
Authors: İLHAN İlter , BÜYÜKBAYRAM Halil İbrahim 
Published: March 2023

Objective
Cadmium (Cd) is a very toxic and carcinogenic heavy
metal that can cause harmful effects on human health.
Toxicity may develop due to Cd exposure, especially in
the kidneys. Ankaferd blood stopper (ABS) is a herbal
mix that is used for its hemostatic properties in surgery.
Also, ABS enhances wound and tissue healing. In this
study, we aimed to evaluate the possible ameliorative
effects of ABS in Cd-induced renal damage.
Material and Method
Thirty-two male rats were randomly divided into 4
groups: control, Cd (cadmium chloride, 2.5 mg/kg
single dose, ip), ABS (ABS, 1.5 ml/kg single dose ip),
and Cd+ABS (cadmium chloride, 2.5 mg/kg single dose
ip- ABS, 1.5 ml/kg single dose ip). At the end of the
experiment, urea and creatinine levels were analyzed
from the rats’ serum. In addition, total oxidant status
(TOS), total antioxidant status (TAS) levels, superoxide
dismutase (SOD), and glutathione peroxidase (GPx)
activity were measured spectrophotometrically
from renal tissues. The oxidative stress index (OSI)
was calculated from TOS and TAS levels. Also, we
evaluated alterations in the mRNA expression of Bcl-
2-associated X protein (Bax), B-cell-lymphoma-2 (Bcl-
2), silenced information regulator 1 (SIRT1), and p53
in kidney tissue of rats by using the qRT-PCR method.
Results
In the Cd group, serum urea, creatinine levels, and
tissue oxidative stress markers, TOS and OSI were
significantly higher while Gpx activity was significantly
lower than in the control group (p
Nuevas metodologías de e-salud. La relación asistencial para una población que envejece
Authors: Benvenga Luca 
Published: March 2023

El envejecimiento de la población conlleva un cambio en la relación entre la población activa y la inactiva. En consecuencia, se produce un aumento en la carga socioeconómica de los costes de atención a las personas de edad avanzada. Así, si, por un lado, el envejecimiento de la población es un indicador positivo de mayor longevidad, por otro lado, presenta numerosos retos a los que hay que hacer frente en el ámbito nacional y europeo, en lo que se refiere al diseño de nuevas políticas sociales y culturales destinadas al empowerment de un segmento creciente de ciudadanía al que hay que sensibilizar en la participación activa en su propia salud.
La hipótesis de este artículo se basa en considerar que la fase histórica actual requiere promover y consolidar los cuidados con nuevas soluciones TIC centradas en la e-salud. A este respecto, también mostraré cómo se requiere una estrecha colaboración entre los actores privados, dedicados a diseñar y perfeccionar los diferentes sistemas digitales de atención y seguimiento, y el sistema sanitario, en un contexto de progresivas transformaciones de los hábitos culturales y de las relaciones asistenciales que, sin embargo, presentan deficiencias.
Lugares de memoria de la pandemia del coronavirus en el contexto de la ciudad de Madrid
Authors: Almazán Cabetas Rodrigo 
Published: March 2023

Este trabajo se plantea como una inspección prospectiva sobre los procesos de patrimonialización y espacialización cultural de la pandemia del coronavirus, habiendo pasado ya más de dos años desde su impactante irrupción. De esta forma, se observan las prácticas y discursos realizados desde las posiciones hegemónicas y subalternas. Por otra parte, se indaga sobre la convivencia de estos espacios con otros lenguajes espaciales de la memoria preexistentes, así como su presencia en el contexto geográfico de una ciudad global como Madrid, con sus procesos de turistificación y metropolización que se producen de forma paralela.
En resumen, se trata de descubrir la manera en la que la pandemia va a contarse por medio de todo tipo de representaciones en el espacio público (calles, plazas, placas o monumentos, entre otras manifestaciones). Además, se analiza cómo estos imaginarios simbólicos se infiltran en la construcción de lo que llamamos memoria colectiva. Asimismo, se trata el caso de los espacios que, durante esta crisis, tuvieron que adaptarse para funciones sanitarias o funerarias, aunque no se habían diseñado para ello; en concreto, se reflexiona acerca de cómo van a retomar sus actividades anteriores y qué marcas representativas tendrá el paso de la pandemia por ellos.
Airway assessment: Predictors for difficult intubation – A prospective observational study
Authors: Kumar Maddala Surya , Zachariah K Varghese , Joel J Chakravarthy 
Published: March 2023

Airway management remains an important challenge in the contemporary practice of anaesthesia and preoperative airway assessment facilitates appropriate preparation when difficulty with intubation or ventilation is anticipated prior to induction of anaesthesia.: Aim: To study the important predictors for difficult laryngeal intubation. To determine the predictors of difficult laryngeal intubation. Secondary: To determine the most significant predictor for difficult intubation and to determine the incidence of unanticipated difficult intubation.This single centre prospective observational study done in Bangalore Baptist hospital (after obtaining clearance from ethical committee) included adult patients posted for elective surgeries who received general anaesthesia. Patients of either gender in the 18 – 65 year age group, with an American Society of Anaesthesiologists physical status classification of I or II, who required endotracheal intubation for general anaesthesia. The sample size was 413 with confidence level 95%. In our study the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of Mallampati class were found to be 75.8%, 78.06%, 37.90%, 94.80% respectively. The sensitivity, specificity, PPV and NPV of mouth opening were found to be 33.87%, 81.19%, 24.13%, 87.42% respectively. The sensitivity, specificity, PPV and NPV of upper lip bite test found to be 27.41%, 96.29%, 56.66%, 88.25% respectively. The sensitivity, specificity, PPV and NPV of neck extension found to be 54.83%, 92.59%, 56.66%, 92.06% respectively. The sensitivity, specificity, PPV and NPV of BMI found to be 53.22%, 75.49%, 27.73%, 90.13% respectively. The incidence of difficult intubation was 15%.:In conclusion, no single predictor is sufficient for prediction of difficult intubation on its own. All the studied bedside tests are poor to moderate predictors of difficult intubation. All the tests showed poor positive predictive values and high negative predictive values which suggests that they can be more useful predictors of easy intubation than difficult intubation.
Comparative study between tramadol and dexamethasone as an adjuvant to bupivacaine in supraclavicular brachial plexus block
Authors: Nagar Kriti 
Published: March 2023

: Brachial plexus block is widely used as an efficient and cost effective alternative to general anesthesia for upper limb surgeries. A variety of adjuvants to local anesthetics have been used and compared, however, drugs which prolong the duration of anaesthesia and analgesia are being constantly studied for patient satisfaction and cost effectiveness.: Prospective, Interventional, Randomised study was conducted over 105 patients scheduled for elective upper limb surgeries under brachial plexus block, who were randomly allocated into three groups of 35 patients each. Group I- Bupivacaine with Tramadol, Group II- Bupivacaine with Dexamethasone and Group III- Bupivacaine alone. The time of onset and duration of sensory and motor block was noted. Hemodynamic variables were measured from baseline until the use of first rescue analgesic. The statistical analysis was done using SPSS (Statistical Package for Social Sciences) version 15.0 statistical analysis software.: Onset of sensory and motor blockade was significantly earlier in Group II (9±1.83 min) and (14.14±3.53min) as compared to Group I (11.94 ±2.59min) and (22.86±3.70min) and Group III(19±5.26min) and (27.14±4.07min). The requirement of first rescue analgesic was significantly earlier in Group III patients (211.43±23.25 min) followed by Group I (397±20.15 min) and last in Group II (632.43±23.15 min).: Bupivacaine with Dexamethasone provided an early onset of sensory and motor blockade with maximum duration of blockade requiring rescue analgesic at a much later time period compared to Bupivacaine with Tramadol and Bupivacaine alone when used in supraclavicular brachial plexus block.
Interventions required and outcome in pregnancy induced hypertension patients in Intensive Care Unit: An observational study
Authors: Raghuveer Bhairavi T. , Sundrani Omprakash , Sahare Kamal Kishore , Shah Pratibha Jain , Lalwani Jaya 
Published: March 2023

Hypertensive disorders of pregnancy, particularly preeclampsia, eclampsia remain one of the leading causes of maternal morbidity and mortality worldwide. We studied the association between the risk factors, interventions required, diagnosis and outcome in these patients admitted to the Intensive Care Unit (ICU).: We conducted a prospective, observational study after the Institutional Scientific and Ethics committee approval. The Institutional record was taken to identify 70 women with Pregnancy Induced Hypertension (PIH) admitted to ICU after meeting the inclusion and exclusion criteria. Socio-demographic details, indication and timing of ICU admission were noted. On ICU admission; baseline vitals, detailed history, duration of complications, therapeutic interventions, laboratory parameters and imaging were compiled. Maternal outcome was assessed in terms of interventions needed, complications encountered and mortality or discharge and follow up was done up to 6 weeks postpartum. Fetal outcome was assessed in terms of live births or Intrauterine fetal death (IUFD), Apgar score, term/preterm and followed up to 7 postnatal days.: It was observed that out of 70 women enrolled in our study, 48 women were diagnosed with preeclampsia, 54 belonged to the age group of 21-30 years, 61 were unregistered for antenatal checkup, 46 had term gestation, 52 were nulliparous and 64 underwent Lower segment caesarean section (LSCS). 60 of them had postpartum ICU admission, all of them had significant rise in blood pressure. Most common interventions were transfusion of blood products (n=30) and mechanical ventilation (n=6). HELLP syndrome was the most common complication (n=7). Maternal mortality was seen in 6 women. 35 neonates had low birth weight, 6 had intra uterine growth retardation (IUGR), 19 were preterm and Apgar score was significant at 5 minutes.: From our observations, it can be concluded that majority of the women were diagnosed with preeclampsia, were relatively of younger age group, nulliparous with no antenatal checkup, underwent LSCS and were admitted postpartum to ICU. Transfusion of blood products was the most common intervention & HELLP syndrome was most common complication. Maternal mortality was higher in women with preeclampsia although overall mortality was low. The incidence of low birth weight, IUGR and preterm neonates was more in eclamptic women. Neonatal mortality was more in preeclamptic women.
A retrospective study of d-dimer level comparison and its prognostic importance in hospitalized COVID-19 patients
Authors: Dias Anusha Leah , Harshavardhan K  
Published: March 2023

Patients with covid-19 have an abnormal coagulation function and the association between D-dimer levels and the severity of COVID-19 is unclear. The study aimed to explore the association between the severity of COVID-19, influencing factors, and D-dimer levels in vaccinated and unvaccinated individuals.In a retrospective study, all patients who are SARS-CoV-2 RNA PCR positive were assessed and detailed vaccine history and laboratory findings were collected. Data were analysed using SPSS version 27.Among 80 study participants, 46 (57.5%) were vaccinated with at least one or two doses and 34 (42.5%) were unvaccinated. 19 (23.8%) study participants were dependent on non-invasive ventilation and 43.8% were on mechanical ventilation. The median D dimer level at day 1 was comparatively higher among vaccinated (median =653.00) compared to their counterpart (median =531.50) and it was no statistically significant difference on day 1 among both the groups (p-value =0.422). Similarly, the median dimer level at day 5 was comparatively higher among vaccinated (median =944.50) compared to non-vaccinated. (median =934.00) and p value =0.422. The study reveals that 7(36.8%) of the vaccinated participants were on non-invasive ventilation and 12(63.2%) non-vaccinated individuals were on non-invasive ventilation and the association was found to be statistically significant (p-value =0.037). The severity of COVID-19 is higher among non-vaccinated (53.8%) than vaccinated (46.2%).D-dimer levels were raised in both vaccinated and unvaccinated individuals. The vaccinated group was at less risk for complications and less need for intubation and mechanical ventilation. Though higher levels of D- dimer were recorded on day 1 and day 5 in vaccinated compared to non-vaccinated statistically it was not significant. We conclude D-dimer levels cannot be utilized as biomarkers for the severity of the disease in vaccinated and non-vaccinated individuals.
Comparative evaluation of intrathecal dexmedetomidine and clonidine as an adjuvant to bupivacaine in gynaecological surgeries
Authors: Dwivedi Gaurav , Gupta Lalit 
Published: March 2023

: Spinal anaesthesia is commonly used in gynaecological surgeries, with Bupivacaine being the most commonly used anaesthetic. Bupivacaine, on the other hand, has a shorter duration of action.This clinical study was conducted to evaluate the behaviour of intrathecal clonidine and dexmedetomidine as an adjuvant to bupivacaine in augmenting block characteristics in patients undergoing gynaecological procedures. A randomised controlled trial was conducted to compare intrathecal Dexmedetomidine and Clonidine as adjuvant to Bupivacaine in gynaecological surgeries. A total of 200 patients were divided into 100 groups, each randomly assigned to one of two groups, and intrathecal medication was administered according to the group assigned. The onset and duration of sensory and motor blockade, the highest level of sensory blockade, analgesia duration, and side effects were all evaluated.: Although the time of onset of sensory and motor block in the Dexmedetomidine group was comparable to the Clonidine group, the two-segment regression time was higher in the Dexmedetomidine group as compared to the Clonidine group. The motor block onset according to Bromage grade-3 was 4.1±1.1 minutes and 4.42±1.2 minutes among Dexmedetomidine and Clonidine groups. Throughout the perioperative period, the central tendency values of mean arterial pressures and heart rate remained consistent in both groups. Postoperative analgesia planning and management start from pre-anaesthetic evaluation. So, the analysis revealed that when combined as an intrathecal adjuvant with bupivacaine, dexmedetomidine not only provides better postoperative pain relief than clonidine but also a significantly longer sensory and motor block with preserved hemodynamic stability and lack of sedation.
A peripheral nerve stimulator guided popliteal sciatic nerve block combined with adductor canal block in lower leg surgery- A sole anesthetic technique
Authors: Chauhan Darshit , Bhamri Stuti , Shah Neha , Syed Afroza N 
Published: March 2023

In lower leg surgeries involving fractures of distal tibia, ankle surgeries, debridement and PVD surgeries choice of anesthesia is usually regional anesthesia. When these patients are associated with co-morbid cardio-respiratory problems then it will become challenge for anesthesiologist to maintain homeostasis with good surgical anesthesia. Ayukut urfalioglu suggested another alternative technique in the form of Adductor canal block plus Lateral approach popliteal sciatic block as good alternative for these surgeries with better Intra-operative Haemodynamic Stability, additional post-operative pain relief and less requirement of systemic analgesia post-operatively.In this prospective randomised controlled trial, we aim to explore the efficacy of Adductor canal block plus Popliteal Sciatic Block for Lower leg surgeries. Sixty patients (ASA I, II, III) undergoing lower limb surgeries were randomly allocated in 2 groups (30 patients in each group). In Group P patients received PNS guided Adductor canal block combined with popliteal sciatic block and in group S patients received unilateral spinal anesthesia.: The primary objectives were to evaluate duration of sensory and motor block and post-operative pain relief. Secondary objectives included intra operative requirements of additional anesthesia and intraoperative haemodynamic stability.There was significant intraoperative haemodynamic stability and post-operative pain relief attributable to Group P. Time for first requirement of rescue analgesia post-operatively was significantly higher in Group P compared to Group S (Group P Mean SD15.9±5.26 vs 6.05±1.23 in Group S with p= &#60; 0.0001).Combined adductor canal block and popliteal sciatic block can be an alternative technique with advantage of prolonged post-operative analgesia and haemodynamic stability.
A questionnaire research on the practice of postoperative anaesthetic visits
Authors: Madhusudhana Ravi , Balasubramaniam Aswin 
Published: March 2023

As early as in 1934 the idea and relevance of post anesthesia visits have been implemented, with the recommendation that anesthesiologists should follow up i.e.; visit their patients regularly in the first two days after surgery to obtain information about the patient’s condition. Sparse literature exists regarding the importance of post anaesthesia visits, currently there are no studies done on how post anaesthesia visits are performed and documented. To find a solution for these issues, we had conducted a questionnaire research on the practice of post anesthesia visits among anaesthesiologists.: The aim of this study is to know whether anesthesiologists does regular post operative anaesthesia visits and to know the importance of post anaesthesia visits.A validated; self-reported electronic questionnaire was used to collect the data from a total of 80 anaesthesiologists who willfully participated in the study. The questionnaire generated using Google forms was sent to consultant as well as resident anaesthesiologists including free-lance practitioners through electronic mail.90% of the participants were resident anaesthesiologists and the rest were consultants. 93.8% of the responders reported that post anaesthesia visits are mandatory at their work place. 91.3% of the participants significantly anaesthetize up to 4 cases on an average per day (p&#60;0.001%). Most of the responders (93.8%) had responded that Post Anesthesia Visits is mandatory in their workplace and documentation of post anaesthesia visits are done mostly in the pre anaesthetic evaluation sheets. Post anaesthesia visits for all high-risk cases on daily basics shows a significant p value (p&#60;0.001%). Daily post anaesthesia visits for all cases on the evening on the day of surgery (p&#60;0.047%) for all cases anaesthetize by the responders for a minimum duration of 10 minutes per patient shows the significant p value (p&#60;0.028%). Post anaesthesia visits are done on a daily basis and documented in pre anaesthetic evaluation sheets or daily progress charts helps in detecting adverse effects related to anaesthesia procedure.
Music in medicine: An overview
Authors: Halder Abhishek , Nishad Ashok Kumar , Halder Ashutosh 
Published: March 2023

Music in medicine is in use in various medical areas like neurological disorders, developmental abnormalities, psychiatric disorders, addictive disorders, terminal disorders, etc besides perioperative care. Music in perioperative care is aimed at reducing anxiety, stress, and fear besides decreasing postoperative pain. The authors (first two) have experience in the use of pre-recorded music medicine in perioperative patient care. Preoperative music is mainly used to reduce patients’ anxiety, stress, and fear. The use of intraoperative music is controversial in surgical procedures under general anesthesia. Postoperative music, in general, is beneficial for pain management. This write-up provides an overview of published information on music in medicine, including historical and in particular perioperative care in anesthesia practice including use in cesarean section delivery. We searched PubMed and PubMed Central besides google search on “music in medicine” up to March 2022. There was no language restriction. Almost all present studies were conducted by listening to pre-recorded music, mostly via headphones. This work indicates that music in medicine, in particular music therapy, has been in use since ancient times (before the common era) and is presently incorporated intermittently in perioperative care. Music in medicine may have a beneficial effect on perioperative care. Music is inexpensive, easily administered, and without adverse effects, and can serve as a complement for reducing perioperative stress and pain besides its beneficial effects on cardiovascular & respiratory systems. Therefore, we conclude that music interventions may provide a viable adjunct to perioperative care. However, music in medicine is still an important research area and needs more properly conducted research before introduction into routine practice.
Total Knee Arthroplasty Followed – Up 8 Years
Authors: Phúc Lê 
Published: March 2023

A female 62 years old, with late osteoarthritis of left knee was performed a Total Knee Arthroplasty (TKA). Cemented femoral and tibial components; removal of patellar osteophytes. Knee valgus 30, sacrifice PCL (Posterior Cruciate Ligament). First 3-month follow-up: no infection, no dislocation, range of motion: 0/0/900, walk no pain, knee score: 90/100. 8-year follow-up : walk, slight run no pain; range of motion: 0/0/1000; knee score evaluated excellent: 95/100. The functional final outcome of this case is a superiority illustration of Total Knee Arthroplasty for the osteoarthitis, especially in the late stage.
PEMBERIAN KOMISI DALAM PENYITAAN SEPEDA MOTOR LEASING SEPIHAK YANG MEMAKAI JASA DEBT COLECTOR
Authors: Saputra Dwi dicki , Fauziah Fauziah , Lubis Ramiah 
Published: March 2023

ABSTRAK
Hasil penelitian yang didapat dalam penelitian ini sistem Pemberian komisi bagi Debt Collector dalam penyitaan sepeda motor leasing sepihak pada PT. Adira Dinamika Multi Finance, Tbk Palembang. yaitu apabila nasabah membayar uang tunggakan kredit sepeda motor, maka debt collector akan diberi komisi sebesar 10% dari uang yang dibayar oleh nasabah, dan apabila debt collector menarik kembali kendaraan sepeda motor nasabah yang sudah jatuh tempo maka debt collector akan diberi komisi sesuai jenis, keadaaan serta tahun dikeluarkannya sepeda motor tersebut pandangan Hukum Ekonomi Syariah terhadap pemberian komisi kepada debt collector dalam penyitaan sepeda motor leasing sepihak PT. Adira Dinamika Multi Finance, Tbk Palembang. Didalam Al- Qur‟an tidak dijelaskan tentang seberapa kita harus membayar komisi, akan tetapi harus diliat dari kondisi perekonomian sekarang sebaiknya komisi yang diberikan kepada Debt collector tersebut harus 50% dikarenakan resiko dari pekerjaan tersebut sangat lah berat. Jenis penelitian ini merupakan Field research dengan studi yang dilakukan di lokasi penelitian.

Kata kunci: Pemberian komisi kepada Debt Collector, Dalam Hukum Ekonomi Syariah.