bluuebunny/crossref_metadata_2025_split huggingface dataset:
Commentary: Is Australian headspace socioculturally westernised, educated, industrialised, rich and democratic in conceptualisation and accessibility?
Authors: Looi Jeffrey CL , Kisely Stephen R , Bastiampillai Tarun , Allison Stephen 
Published: February 2023

Objective The Australian headspace model has been proposed as an internationally significant exemplar for reducing the mental health ‘treatment gap’ amongst young people around the world. We provide a commentary that discusses the conceptualisation and delivery of headspace services within Australia, a predominantly Westernised, Educated, Industrialised, Rich and Democratic (WEIRD) society, as well as examining accessibility and suitability for culturally and linguistically diverse (CALD) communities. Conclusion headspace was conceptualised, designed, implemented and evaluated according in a WEIRD sociocultural context, and is therefore most applicable to that setting. Australia also has CALD communities, who have not seemed to access headspace in the reported patient and staff demographics. On this basis, there may be questions about the potential generalisability of headspace models outside WEIRD societies.
The prevelance of psychosis in indigenous populations in Australia: A review of the literature using systematic methods
Authors: Jewell James , Mitchell David 
Published: February 2023

Objectives To understand the prevalence of psychosis in Aboriginal and Torres Strait Islander populations. Methods A systematic review of the literature was conducted using PubMed, Embase and Cochrane. Results Eight studies were reviewed. The prevalence of psychosis appeared higher in Aboriginal and Torres Strait Islanders, compared with non-Aboriginal and Torres Strait Islander populations. Conclusion Although the literature suggests the prevalence of psychosis in Aboriginal and Torres Strait Islander populations is substantial, there are few studies and limited scope. Cultural competency is essential to understanding psychosis in this context.
US-guided central venous catheter placement in the neonatal intensive care unit: Brachiocephalic vein or internal jugular vein?
Authors: Osman Dere , Mehmet Kolu , Halil Kazanasmaz 
Published: February 2023

Background: Centrally inserted central catheters (CICCs) are commonly used to monitor venous pressure and administer parenteral nutrition and drugs in newborns. In the present study, we evaluated cannulation success rates, cannulation time, and frequency of complications in catheterization of the internal jugular vein (IJV) and brachiocephalic vein (BCV). Methods: The present study included patients who underwent IJV and BCV catheterization under ultrasound (US) guidance. The patients were divided into two groups, IJV and BCV, depending on the vein in which the CICC was utilized. We documented the diameters of the IJVs and BCVs, first attempt and overall success rates, mean cannulation time, and complication rates. Results: A total of 79 patients were evaluated, 37 in the BCV group and 42 in the IJV group. No significant differences were observed between the two groups in terms of sex, mean age, or weight range ( p > 0.05).The mean vein diameter was significantly larger in the BCV group than in the IJV group ( p < 0.001); the mean number of attempts was significantly higher in the IJV group than in the BCV group ( p < 0.001); the mean cannulation time was significantly longer in the IJV group than in the BCV group ( p < 0.001); and the first attempt success rate was 50% in the IJV group, versus 94.6% in the BCV group. The overall success rate was 100% in both groups. The rate of complications was 8.6% in the IJV group, while no complications developed in the BCV group. Conclusions: Given the larger diameter of the vessel, BCV catheterization was found to result in quicker cannulation and lower complication rates. The results of the present study suggest that BCV catheterization should be the first choice for neonatal intensive care unit (NICU) patients who require parenteral support or close venous pressure monitoring.
Direct Percutaneous Thrombolysis (DPT): A novel method of salvaging Thrombosed Native Arteriovenous Fistula
Authors: Prasad Raghunandan , Vignesh Selvamurugan , Yadav Rajanikant R , Sharma Srishti , Hasani Prerna , Yadav Tanya , Israrahmed Amrin , Lal Hira 
Published: February 2023

Introduction: Thrombosed arteriovenous fistulas (AVFs) are either treated by thrombectomy or pharmaco-mechanical thrombolysis with or without percutaneous balloon angioplasty. In this study, we have described an effective and economical technique of salvaging these fistulae using a 20–22-gauge spinal needle and urokinase and have named it direct percutaneous thrombolysis (DPT). Materials and method: This prospective study comprised of 148 patients out of which 120 patients presented with AVF thrombosis and were divided into two groups; those with no obvious stenosis on ultrasound ( n = 38) and second with venous stenosis ( n = 82). Remaining 28 patients developed thrombosis post angioplasty for venous stenosis. Percutaneous injection of urokinase into the thrombus was done under ultrasound guidance, followed by balloon angioplasty if there was associated stenosis. Results: In 38 patients who didn’t have any stenosis, 32 AVFs were successfully thrombolysed by DPT, with technical success of 84.2%. Remaining six patients required angioplasty because of chronic nature of clot. In 82 patients who had venous stenosis, 80 cases were treated successfully by DPT followed by angioplasty with technical success of 97.5%. In third group ( n = 28), who developed thrombosis post angioplasty, 100% success rate was noted. The mean length of thrombus was 31.4 ± 4.6 mm and mean diameter of thrombosed vein was 10.5 ± 1.2 mm. There were no major complications encountered during the procedure. Minor complications were seen in 19 patients which included prolonged oozing from puncture site and local hematoma formation. Conclusion: Ultrasound guided DPT with urokinase is a safe and economical option for salvaging thrombosed AVF without vascular stenosis that does not need angioplasty.
Revision of Failed Radial Head Arthroplasty
Authors: Heifner John J. , Kolovich Gregory P. , Bolano Luis E. , Sibley Paul A. , Gonzalez Gilberto A. , Mercer Deana M. 
Published: February 2023

Background: Revision of radial head arthroplasty (RHA) may be indicated in cases of prosthesis loosening and malposition. Inherent difficulties in revision surgery include poor bone stock and disrupted soft tissue envelope. Although cases of RHA used for revision of failed RHA are rare, there is reasonable expectation for increasing frequency of these cases due to the increasing incidence of primary RHA. Furthermore, there is an increasing demand for postoperative recovery of function; thus, surgeons may consider revising a failed RHA to a new RHA. We report on series of failed RHA which were revised to a new radial head prosthesis. Methods: A retrospective review was performed at multiple institutions for a single radial head prosthesis used for revision of a failed radial head prosthesis. Clinical and radiographic outcomes were collected with a minimum of 1 year of follow-up. Results: Across 11 patients at a mean follow-up of 45.1 months, the mean Mayo Elbow Performance Score was 81.7; mean Disabilities of the Arm, Shoulder, and Hand scores were 24.4; and mean Visual Analog Scale for pain was 0.6. Radiographic analysis yielded no evidence of capitellar wear or stem loosening. Conclusion: A radial head prosthesis can produce satisfactory results when used for revision of a failed prosthesis. Inherent difficulties in revision surgery include the potential for reduced bone stock and a disrupted soft tissue envelope. Elements of prosthesis design which may contribute to effectively managing revision surgery include a long stem with in-growth surface and prosthetic head alignment to the axis of forearm rotation.
Clinical perspective in relation to age in patients treated with thrombectomy for anterior circulation stroke in a stroke center in Colombia
Authors: Cárdenas Sauder A , Vásquez Andrés , Ortiz Andrés F , Correa Paula A , Vera Daniela D , Ramírez Diego A , Florez Maria A , Ochoa Miguel E , Galvis Melquizidel , Vargas Oliverio , Ferreira Carlos A , Mantilla Daniel 
Published: February 2023

Background and aims Endovascular treatment for cerebrovascular disease is accepted as a first-line option with level I evidence in patients with an early and late time of window of onset symptoms, and an additional option in patients who do not respond or with contraindications to systemic thrombolysis; nevertheless the efficacy and outcomes of some groups were not clear, one of them are patients aged 80 years and older, because they were excluded of the trials, so the evidence is controversial with significant heterogeneity, for that reason in our study, we decided to analyze the age in the patients treated in our stroke center, as a predictor of prognosis, and to provide a baseline for the establishment of personalized treatment plans. Methods Observational, retrospective study of patients that received endovascular treatment for cerebrovascular disease in a Colombian stroke center between 2016 and 2020, continuous and categorical variables were compared using the Student's t test and Chi-Square. To determine cut-off points in the variable against death and Rankin score variable on 90th day. Results In total, 108 patients were recruited, 35 of them were of 80 or more years, and the mean age was 72.7 years, we found age as a significant variable to predict the risk in the population over 80 years of age [RR 3.37 CI (95% 1.14–103) p  =  0.029]. Conclusions Age younger than 80 is a significant predictor for results and long-term outcomes in patients suffering from stroke, and in patients older than 80 years old a Thrombolysis in Cerebral Infarction score 2b-3 is a predictor of good outcomes. Further studies are needed to evaluate the relationship between intrahospital complications and long-term outcomes.
Safety and feasibility of the Wahoo Hybrid Access System, a dual-mode guide catheter, in a range of neuroendovascular procedures
Authors: Waters Michael J , Vargas Jan , Turk Aquilla , Chaudry Imran , Turner Raymond D 
Published: February 2023

Background There is a clinical need for a guide catheter with combined stability and navigability, which can be used in a biaxial system for neuroendovascular procedures in place of triaxial systems. Objective To assess the safety and feasibility of the Q’Apel Medical Wahoo Hybrid Access System, a dual-mode 0.072″ internal diameter guide catheter, in a range of neuroendovascular procedures. Methods We performed a retrospective analysis of consecutive cases from a high-volume tertiary center in which the Wahoo Hybrid Access System was used as the guide catheter. Characteristics of the patients, vascular lesions, procedure, and procedural complications were assessed. Results A total of 102 patients were included for analysis. Vascular lesions were in the anterior circulation in 90 of 102 (88%), and posterior circulation in 12 of 102 (12%). Eighty-four cases were ruptured or unruptured aneurysm embolization procedures, the majority being balloon-assisted coiling (42%) and flow diversion (42%). All cases, including flow diversion, were performed as a biaxial system. There were no instances of prolapse of the catheter beyond the arterial segment in which it was initially placed. The procedure was able to be performed to completion in 101 of 102 (99%) cases. Thromboembolic complications occurred in 5 of 102 (5%); causality in two cases was unrelated to the guide catheter, and three were indeterminate. Conclusions The Wahoo guide catheter is safe and feasible when used in a variety of neuroendovascular procedures. It can accommodate a range of devices, can be safely navigated into distal vasculature, and provides support for a range of procedures, including those which traditionally require triaxial support.
The 50 most-cited articles in reverse shoulder arthroplasty
Authors: Gross Benjamin D , White Christopher A , Wang Kevin C , Patel Akshar V , Parsons Bradford O , Cagle Paul J 
Published: February 2023

Background Citation analyses have been used to understand the impact that a group of publications has on its field. As the techniques and indications of reverse total shoulder arthroplasty (RTSA) continue to expand, it is important to identify articles that can orient readers to the history, evolution, and current status of the body of RTSA literature. The purpose of this study was to identify and analyze the 50 most-cited articles related to RTSA. Methods Various Boolean queries were searched on the Clarivate Analytics Web of Science. Information collected included author name, publication year, country of origin, journal name, article type, total number of citations, and level of evidence. Results Top 50 most-cited articles amassed a total of 10,521 citations. The most-cited article was cited a total of 766 times. The most common study designs were case series (28) and cohort studies (9). Authors from the United States (24) contributed the most to included papers, followed by France (19) and Switzerland (8). Discussion The most-cited articles on RTSA are expert opinions, case studies, and cohort studies published by American authors. As RTSA continues to grow over the next decade, studies with higher levels-of-evidence may overtake articles included in this analysis.
Delayed Presentation of Actinomycosis Following Orthognathic Surgery: An Old Nemesis and a Difficult Diagnosis: Case Presentation and Review of the Literature
Authors: Krisko Alexander J. , Van Sickels Joseph E. 
Published: February 2023

Study Design Review of the literature with report of Case. Objective To review the presentation of Actinomycosis specifically as it occurs with mandibular osteotomies. Methods A review of the literature and report of an additional case. Results While minor infections secondary to local factors are usually seen 2–3 weeks after surgery, late infections are rare. Host factors may play a role. When actinomycosis is diagnosed, long-term antibiotics are necessary. Conclusions Actinomycosis is very rare following orthognathic surgery. It usually occurs in the mandible and following a sagittal split. Time of presentation for actinomycosis can vary from 6 weeks to 4 months as in our case. Infections occurring this late after surgery should be treated with suspicion of actinomycosis obtaining both cultures and tissue biopsies. Treatment involves an incision and drainage and long-term antibiotics.
A systematic review of the tensions between the public and private in adolescents’ social networks: New education challenges
Authors: González-Villa Ángela , Gewerc Adriana 
Published: February 2023

Social networks are colonised by a culture of confession that turns teenager privacy into a commodity to achieve recognition and social acceptance. This display accelerates the porosity of the boundaries between the public and the private and feeds surveillance capitalism. The aim of this systematic review is to examine the empirical evidence on the public-private interaction of teenagers’ contributions to social networks in the last 5 years in databases: Eric, Scopus and Web of Science. Based on the Prisma Statement, the initial search produced 1449 documents, of which 81 were included in the final analysis after the application of exclusion and inclusion criteria and the purging of duplicates. The results show a field of study developed with a decreasing trend in production in recent years, knowledge gaps and discordant findings. It is concluded the need to build solid knowledge and initiate new lines in the study of the issue in order to understand the exhibition of teenagers in social networks. It is points out the urgency of a training based on their own media practices and in digital literacy for a broad understanding of online privacy.
Biofeedback EMG alternative therapy for chronic low back pain (the BEAT-pain study)
Authors: Lazaridou Asimina , Paschali Myrella , Vilsmark Eric S , Sadora Jason , Burton Dustin , Bashara Annie , Edwards Robert R 
Published: February 2023

Objective The aim of this study was to assess the feasibility and potential effectiveness of an 8-week virtual EMG biofeedback intervention for patients with CLBP. Methods Patients with CLBP completed validated baseline and post-intervention assessments of pain intensity and interference (Brief Pain Inventory), back pain-related disability (Oswestry Disability Index), anxiety and depression (Hospital Anxiety and Depression Scale). Participants underwent a series of Quantitative Sensory Testing (QST) procedures assessing responses to mechanical stimuli during two separate visits (baseline and post-intervention). In addition, we assessed, using surface EMG, the muscle tension in the trapezius, latissimus, and low back muscles at each session. Patients were randomized into the EMG biofeedback intervention or usual care group. Factorial analysis of variance including the interaction between treatment group and time was used to analyze the changes in pain intensity (primary outcome), pain interference, disability (secondary outcomes), anxiety, and depression (secondary outcomes). Results Compared to the treatment as usual comparison group, patients in the EMG biofeedback group reported lower pain intensity after completing the intervention (mean group difference 0.9, 95% CI −1.07, −0.32; p≤0.01). Compared to baseline, participants in the EMG biofeedback group demonstrated statistically significant reductions in pain interference (mean difference 1.3, 95% CI 0.42, 2.1; p≤0.01), disability (mean difference 4.32, 95% CI 1.2, 7.3; p≤0.01), and significant increases in low back pain thresholds (mean difference 0.5, 95% CI −0.87, −0.05; p≤0.01), assessed by QST. However, no significant group by time effects were observed for secondary outcomes: pain interference, disability, and low back pain thresholds. In addition, significant changes were observed in muscle tension for the trapezius, latissimus, and low back muscles in the EMG biofeedback group ( p<0.001). Conclusions Virtual EMG biofeedback shows promise as a potential therapy for reducing pain and disability in individuals with chronic nonspecific low back pain.
On triangle inequalities of correlation-based distances for gene expression profiles
Authors: Chen Jiaxing , Ng Yen Kaow , Lin Lu , Zhang Xianglilan , Li Shuaicheng 
Published: February 2023

Abstract
Background
Distance functions are fundamental for evaluating the differences between gene expression profiles. Such a function would output a low value if the profiles are strongly correlated—either negatively or positively—and vice versa. One popular distance function is the absolute correlation distance, $$d_a=1-|\rho |$$

d
a

=
1
-

|
ρ
|

, where $$\rho$$
ρ
is similarity measure, such as Pearson or Spearman correlation. However, the absolute correlation distance fails to fulfill the triangle inequality, which would have guaranteed better performance at vector quantization, allowed fast data localization, as well as accelerated data clustering.

Results
In this work, we propose $$d_r=\sqrt{1-|\rho |}$$

d
r

=

1
-
|
ρ
|

as an alternative. We prove that $$d_r$$

d
r

satisfies the triangle inequality when $$\rho$$
ρ
represents Pearson correlation, Spearman correlation, or Cosine similarity. We show $$d_r$$

d
r

to be better than $$d_s=\sqrt{1-\rho ^2}$$

d
s

=

1
-

ρ
2

, another variant of $$d_a$$

d
a

that satisfies the triangle inequality, both analytically as well as experimentally. We empirically compared $$d_r$$

d
r

with $$d_a$$

d
a

in gene clustering and sample clustering experiment by real-world biological data. The two distances performed similarly in both gene clustering and sample clustering in hierarchical clustering and PAM (partitioning around medoids) clustering. However, $$d_r$$

d
r

demonstrated more robust clustering. According to the bootstrap experiment, $$d_r$$

d
r

generated more robust sample pair partition more frequently (P-value $$<0.05$$

<
0.05

). The statistics on the time a class “dissolved” also support the advantage of $$d_r$$

d
r

in robustness.

Conclusion
$$d_r$$

d
r

, as a variant of absolute correlation distance, satisfies the triangle inequality and is capable for more robust clustering.
Association of circulating MtDNA with CVD in hemodialysis patients and in vitro effect of exogenous MtDNA on cardiac microvascular inflammation
Authors: Fan Zhen , Feng Ya , Zang Li , Guo Yi , Zhong Xiao-yi 
Published: February 2023

Abstract
Background
Chronic kidney disease (CKD) patients sustain a fairly high prevalence of cardiovascular disease (CVD). Microvascular inflammation is an early manifestation of CVD, and the released mitochondrial DNA (MtDNA) has been proposed to be a crucial integrator of inflammatory signals. Herein, the aim of this study was to determine the relationship between CVD, microvessel, and circulating MtDNA in the settings of uremia.

Methods
Forty-two maintenance hemodialysis (MHD) patients and 36 health controls were enrolled in this study. Plasma cell-free MtDNA was detected by TaqMan-based qPCR assay. CVD risk markers including high-sensitive C-reactive protein (Hs-CRP), monocyte chemoattractant protein-1 (MCP-1), fibrinogen, and erythrocyte sedimentation rate (ESR) were measured by standard assays. Ten-year CVD risk was calculated from the Framingham risk score (FRS) model. In vitro study, human cardiac microvascular endothelial cells (HCMECs) were incubated with normal or uremic serum, with or without exogenous MtDNA. Intracellular toll-like receptor 9 (TLR9), adhesion molecule 1 (ICAM-1), MCP-1 and tumor necrosis factor-α (TNF-α) and cytosolic MtDNA were detected by qPCR.

Results
Plasma MtDNA in MHD patients was significantly higher than healthy controls (4.74 vs. 2.41 × 105 copies/mL; p = 0.000). Subsequently, the MHD patients were classified into two groups based on the MtDNA median (4.34 × 105 copies/mL). In stratified analyses, the levels of Hs-CRP (5.02 vs. 3.73 mg/L; p = 0.042) and MCP-l (99.97 vs. 64.72 pg/mL; p = 0.008) and FRS (21.80 vs. 16.52; p = 0.016) in the high plasma MtDNA group were higher than those in the low plasma MtDNA group. In vitro study, we found that exogenous MtDNA aggravated uremic serum-induced microvascular inflammation (ICAM-1 and TNF-α) in HCMECs (all p < 0.05). Besides, the addition of MtDNA to the medium resulted in a further increase in cytosolic MtDNA and TLR9 levels in uremic serum-treated cells (all p < 0.05). In patients with MHD, MtDNA levels in plasma were significantly reduced after a single routine hemodialysis (pre 4.47 vs. post 3.45 × 105 copies/mL; p = 0.001) or hemodiafiltration (pre 4.85 vs. post 4.09 × 105 copies/mL; p = 0.001). These two approaches seem similar in terms of MtDNA clearance rate (21.26% vs. 11.94%; p = 0.172).

Conclusions
Overall, the present study suggests that MtDNA released into the circulation under the uremic toxin environment may adversely affect the cardiovascular system by exacerbating microvascular inflammation, and that reducing circulating MtDNA might be a future therapeutic strategy for the prevention of MHD-related CVD.