bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neuroprotective Effect of Morinda citrifolia on Behavioural and Biochemical
Deficits in PTZ-induced Kindled Mice
Authors: Ali Moazzam , Singh Prabhat , Singh Lubhan , Pandey Rupesh Kumar , Soni Priyadarshini , Singh Akansha 
Published: June 2023

Introduction:
Epilepsy is a group of chronic neurological disorders characterized by seizures.
Kindling, a chronic epileptic mouse model, was used to explore the epileptogenic mechanism
and seek new anti-epileptics. In kindling, sub-convulsive (chemical/ electrical) stimuli were delivered
repeatedly and erratically, eventually causing massive convulsions. Moreover, Morinda citrifolia (Noni)
extracts are used as a remedy in ayurvedic preparations for many ailments. Noni has recently been
shown to protect mice from amyloid beta-induced memory loss.

Objective:
This study was used to investigate the neuroprotective potential of Morinda citrifolia in
mice over pentylenetetrazol (PTZ)-induced kindling seizure.

Methods:
Kindling was provoked by subsequent (one-day-gap) injections of PTZ (subconvulsive; 35
mg/kg; s.c.) for 29 days in mice. Following PTZ injection, convulsive behaviours were noted for 30
minutes. Forced swimming test (depressive behaviors), elevated plus-maze, and passive avoidance
tests were employed to evaluate cognition. Brain homogenate was used to estimate oxidative stress
(glutathione, superoxide-dismutase, lipid-peroxidation) and acetylcholinesterase activity.

Results:
PTZ-provoked kindled mice displayed depressive behaviors, impaired locomotion, cognitive
dysfunctions and various biochemical changes. However, treatment with Morinda citrifolia extract
(500 and 1000 mg/kg, p.o) and valproic acid (200 mg/kg, p.o) before 60 min of each PTZ injection
diminished kindling scores and restored behavioural, and biochemical changes.

Conclusion:
Our findings suggest Morinda citrifolia offered neuroprotective effects against PTZinduced
kindling seizures in mice, which were established by behavioural and biochemical paradigms.
Leptotrichia trevisanii: Case Report and Review of the Literature on
Patients with Leptotrichia trevisanii Bacteremia in Acute Myeloid Leukemia
Authors: Chady Awad , Emmanuel Garrastegui-Mercado , Antony Suresh 
Published: June 2023

Background:
Leptotrichia spp. are fastidious facultative anaerobic, pencil-shaped, gramnegative
rods that reside in the mouths, intestines, and female genital tracts of humans. Bacteremia and
septic shock have been rarely reported in the immunocompromised host. We report a case of L. trevisanii
bacteremia in a patient recently diagnosed with acute myeloid leukemia (AML) on chemotherapy.

Case Presentation:
A 75-year-old male with a history of diabetes, chronic kidney disease, and coronary
artery disease status post-CABG presented with neutropenic fevers and signs of sepsis after the
initiation of chemotherapy. Blood cultures were ordered and extensive gene sequencing helped identify
Leptotrichia trevisanii as the causative pathogen. Subsequently, the patient was successfully treated
with empiric cefepime.

Discussion:
Opportunistic pathogens are involved in a variety of diseases and have been isolated from
immunocompromised patients undergoing transplantation or in patients with comorbidities, like leukemia,
lymphoma, or neutropenia. L. trevisanii has been reported as a cause of bloodstream infections
in patients with hematologic malignancies receiving chemotherapy.

Conclusion:
This case highlights the key role that Leptotrichia trevisanii plays in the introduction of
sepsis among immunocompromised patients, particularly with hematologic malignancies, like AML,
on chemotherapy.
Going Green for Blue - An Indigo Approach
Authors: Thadepalli Srivani , Amsamani Sundarvel 
Published: June 2023

Introduction:
Dominating use of chemical processes for reducing indigo at several small-scale
production houses formed the ground for initiating this study. Conventional textile processing hubs still
use sodium hydrosulphite as a reducing agent irrespective of the source of indigo, whether natural or synthetic
ignoring the unfavourable consequences of their disposal and elimination from effluent

Method:
The paper addresses the critical environmental issues related to the conventional reduction of
indigo and studies already undertaken. It examines the indigo dyeing process of cotton using natural,
chemical and eco-friendly reducing agents in combination with calcium hydroxide for a comparative
study. Identification of natural indigo through High-Performance Liquid Chromatography was undertaken
for further experimentation. Under specific parameters, the study examined the effect of Thiourea dioxide
and natural reducing agents in indigo dyeing replacing Sodium hydrosulphite. The difference in weight,
strength, and colour parameters such as K/S (HUNTERLAB), CIELab values and colourfastness are
measured. The experimental results showed weight gain in all fabrics after indigo dyeing. There is a decrease
in weft strength only in tamarind, iron, jaggery and dextrose vats. Iron vat showed a higher colour
yield out of all reducing agents due to forming metal complexes with the cotton fabric, which influenced
colour depth and highest relative colour strength % (114.11) and ΔC (8.48).

Result:
Thiourea dioxide showed the next highest relative colour strength % (96.59) and lowest ΔH values
(8.54) concerning the values of the hydro process. Structural changes of fiber were studied by using
SEM (Scanning Electron Microscope) after using different reducing agents, which revealed superior surface
topography of samples dyed using thiox. The colour difference showed no significant effect on the
colourfastness of alternative reducing agents.

Conclusion:
Thiox can be a perfect substitution for hydro in indigo dyeing as it was found practical and
feasible for implementation even by small-scale units in India.
Exploring the Feasibility and Usability of Smartphones for Monitoring Physical Activity in Orthopedic Patients: Prospective Observational Study
Authors: Ghaffari Arash , Kildahl Lauritsen Rikke Emilie , Christensen Michael , Rolighed Thomsen Trine , Mahapatra Harshit , Heck Robert , Kold Søren , Rahbek Ole 
Published: June 2023

Background
Smartphones are often equipped with inertial sensors that measure individuals’ physical activity (PA). However, their role in remote monitoring of the patients’ PAs in telemedicine needs to be adequately explored.

Objective
This study aimed to explore the correlation between a participant’s actual daily step counts and the daily step counts reported by their smartphone. In addition, we inquired about the usability of smartphones for collecting PA data.

Methods
This prospective observational study was conducted among patients undergoing lower limb orthopedic surgery and a group of nonpatients as control. The data from the patients were collected from 2 weeks before surgery until 4 weeks after the surgery, whereas the data collection period for the nonpatients was 2 weeks. The participant’s daily step count was recorded by PA trackers worn 24/7. In addition, a smartphone app collected the number of daily steps registered by the participants’ smartphones. We compared the cross-correlation between the daily steps time series obtained from the smartphones and PA trackers in different groups of participants. We also used mixed modeling to estimate the total number of steps, using smartphone step counts and the characteristics of the patients as independent variables. The System Usability Scale was used to evaluate the participants’ experience with the smartphone app and the PA tracker.

Results
Overall, 1067 days of data were collected from 21 patients (n=11, 52% female patients) and 10 nonpatients (n=6, 60% female patients). The median cross-correlation coefficient on the same day was 0.70 (IQR 0.53-0.83). The correlation in the nonpatient group was slightly higher than that in the patient group (median 0.74, IQR 0.60-0.90 and median 0.69, IQR 0.52-0.81, respectively). The likelihood ratio tests on the models fitted by mixed effects methods demonstrated that the smartphone step count was positively correlated with the PA tracker’s total number of steps (χ21=34.7, P<.001). In addition, the median usability score for the smartphone app was 78 (IQR 73-88) compared with median 73 (IQR 68-80) for the PA tracker.

Conclusions
Considering the ubiquity, convenience, and practicality of smartphones, the high correlation between the smartphones and the total daily step count time series highlights the potential usefulness of smartphones in detecting changes in the number of steps in remote monitoring of a patient’s PA.
Comparison of The Molecular Docking Properties of Three Potentially Active Agents
Authors: GÖRGÜLÜ Güvenç , DEDE Bülent 
Published: June 2023

Antineoplastic agents are generally the drugs used to recess or prevent tumor growth which is promoted in many cases by certain factors like vascular endothelial growth factor-2 (VEGFR-2) and cyclooxygenase-2 (COX-2). These two factors seem important in angiogenesis and lymphangiogenesis in fetal, normal and neoplastic tissue. Prevention of VEGF family of proteins and cyclooxygenase-2 enzyme is a good strategy to inhibit the growth of tumor tissue eventually may give rise to recession.
In this study, three potentially active and an active ligand were tested for their binding properties to two target molecules mentioned above by molecular docking study. This research is aimed to compare three different molecules according to their binding affinities, binding energies and the nature of bonds formed between the ligand and the target molecules. Showing the 3D structures will localize the fitted ligands on proteins and the possible hydrogen bonds formed were defined. Among the three proposed ligands, Ligand 1 showed the closest results to the commercial product lenalidomide®. All three ligands showed similar ∆G values and fitness scores with lenalidomide® which is an indicator of good fit, proximity and orientation with the target molecule.
Juri Lomba Membuat Poster Digital Kejar Mimpi Jakarta Pemanfaatan Energi Terbarukan dalam Kehidupan Sehari-Hari
Authors: Utoyo Arsa Widitiarsa , Warbung Tobias , Aprilla Hervina 
Published: June 2023

Artikel pengabdian masyarakat ini membahas tentang proses kegiatan lomba membuat poster yang diadakan secara daring oleh kejar mimpi Jakarta PT Bank CIMB Niaga Tbk. Perlombaan yang mempunyai tema pemanfaatan energi terbarukan dalam kehidupan sehari-hari ini diikuti oleh para pelajar dan juga mahasiswa dengan dua kategori sesuai dengan latar belakang peserta. Adapun metode perlombaan yakni dimana peserta lomba mendaftarkan perlombaan yang akan diikuti dan diberi tugas sesuai dengan lomba yang dipilih, untuk pemilihan juara lomba panitia melibatkan tenaga juri seni professional, sesuai dengan system perlombaan merupakan kesepakatan dari pihak penyelenggara yakni kejar mimpi Jakarta dan Dewan juri. Unsur – unsur yang dinilai dalam lomba mewarnai adalah orisinalitas karya, isi dan desain, administratif, kualitas dan deskripsi karya. Selain dari unsur-unsur nilai tersebut para peserta juga diminta untuk mempresentasikan karya mereka dan menjelaskan bagaimana karya diciptakan. Dari unsur tersebut didapatkan pemenang lomba untuk kategori pelajar dengan total nilai sebesar delapan empat untuk juara satu, sedangkan untuk juara dua dengan total nilai tujuh puluh, untuk kategori mahasiswa didapatkan juara satu dengan nilai delapan enam dan untuk juara dua dengan total nilai delapan lima. Dengan diadakannya lomba ini sangat bermanfaat baik dari sisi peserta yang memiliki pengalaman baru, dan dapat memotivasi peserta agar dapat mengembangkan bakat dan minatnya.
Time Series Analysis of Chromophoric Dissolved Organic Matter (CDOM) at Perancak Estuary
Authors: Suryaputra I Gusti Ngurah Agung 
Published: June 2023

This study aimed at determaining the effect of sea tides on changes of CDOM, in-situ parameters and nutrients on Perancak Estuary. The subject of this study was estuary water collected from Estuary Perancak and filtered using GF/F 0.7 μm with help of injection. The objects of this study were CDOM absorbance, nutrients concentration and parameters in-situ. Sampel collected every 1 hour once for 25 hours, were measured in-situ parameters. Filtered estuary water was placed into sample bottles and placed in a box was kept away from light. Absorbance and nutrients concentration were measured using UV-1800 Shimadzu UV-Vis Spectrophotometer. Absorbance spectral slope (S) and E2:E3 were calculated from the absorbance. Result shows that S275-295 and E2:E3 had a negative correlation with water level, while SR did not show any positive and negative correlation with water level. In addition most of in-situ parameters show a positive correlation with water level and some of nutrients show a negative correlation with water level.
Biventricular versus left ventricular only stimulation: an echocardiographic substudy of the B-LEFT HF trial
Authors: Ansalone Gerardo , Boriani Giuseppe , Sassone Biagio , Camastra Giovanni , Donal Erwan , Calò Leonardo , Casella Michela , Delarche Nicolas , Lozano Ignacio Fernandez , Biffi Mauro , Boulogne Eric , Guidotto Tiziana , Leclercq Christophe 
Published: June 2023

Background
The noninferiority of left ventricular pacing alone (LVp) compared with biventricular pacing (BIV) has not been yet definitely documented. In this study, we reviewed all the original echocardiographic measures of the Biventricular versus Left Univentricular Pacing with ICD Back-up in Heart Failure Patients (B-LEFT HF) trial in order to investigate mechanisms underlying LV remodelling with both pacing modalities.

Methods
Patients with New York Heart Association functional class (NYHA) III or IV despite optimal medical therapy, LVEF 35% or less, left ventricular end-diastolic diameter (LVEDD) more than 55 mm, QRS duration at least 130 ms were randomized to BIV or LVp for 6 months. The primary end point was a composite of at least 1 point decrease in NYHA class and at least 5 mm decrease in left ventricular end-systolic diameter (LVESD). An additional end point was a LVp reverse remodelling defined as at least 10% decrease in LVESD. Mitral regurgitation and all echocardiographic measures were reassessed after 6-month follow-up.

Results
One hundred and forty-three patients were enrolled. Seventy-six patients were in the BIV and 67 were in the LVp group. Left ventricular volumes decreased significantly without difference between groups (P = 0.8447). Similarly, left ventricular diameters decreased significantly in both groups with a significant decrease in LVESD with BIV (P < 0.0001), but not with LVp (P = 0.1383). LVEF improved in both groups without difference (P = 0.8072). Mitral regurgitation did not improve either with BIV, or with LVp.

Conclusion
The echocardiographic sub-analysis of B-LEFT study showed the substantial equivalence of LVp in favouring left ventricular reverse remodelling as compared with BIV.
Can first or last name uniqueness help to identify diaspora researchers from any country?
Authors: Thelwall Mike 
Published: June 2023

Abstract

Purpose
Diaspora researchers work in one country but have ancestral origins in another, either through moves during a research career (mobile diaspora researchers) or by starting research in the target country (embedded diaspora researchers). Whilst mobile researchers might be tracked through affiliation changes in bibliometric databases, embedded researchers cannot. This article reports an evidence-based discussion of which countries’ diaspora researchers can be partially tracked using first or last names, addressing this limitation.

Design/methodology/approach
A frequency analysis of first and last names of authors of all Scopus journal articles 2001-2021 for 200 countries or regions.

Findings
There are great variations in the extent to which first or last names are uniquely national, from Monserrat (no unique first names) to Thailand (81% unique last names). Nevertheless, most countries have a subset of first or last names that are relatively unique. For the 50 countries with the most researchers, authors with relatively national names are always more likely to research their name-associated country, suggesting a continued national association. Lists of researchers’ first and last name frequencies and proportions are provided for 200 countries/regions.

Research limitations
Only one period is tracked (2001-2021) and no attempt was made to validate the ancestral origins of any researcher.

Practical implications
Simple name heuristics can be used to identify the international spread of a sample of most countries’ diaspora researchers, but some manual checks of individual names are needed to weed out false matches. This can supplement mobile researcher data from bibliometric databases.

Originality/value
This is the first attempt to list name associations for the authors of all countries and large regions, and to identify the countries for which diaspora researchers could be tracked by name.
The International North-South Transport Corridor: The Prospects and Challenges for Connectivity between Russia and India
Authors: Zakharov Aleksei 
Published: June 2023

Connectivity has been one of the most challenging issues for developing trade cooperation between Russia and India. Due to the geographic distance separating the two nations, along with the unstable security environment in Afghanistan and border disputes between India and Pakistan, the creation of a direct and shortest transport route has proven difficult, thereby rendering it impossible to implement crucial projects in energy infrastructure.This paper briefly outlines the functioning logistics between Russia and India, which has relied primarily on shipping through the Suez Canal, with an emphasis on the developments in the wake of conflict in Ukraine. The author briefly explores the prospects for maritime connectivity between the Russian Far East and Indian ports, and highlights several challenges for launching a regular Vladivostok-Chennai corridor.The US and European sanctions against the Russian economy, combined with subsequent difficulties in transporting goods by sea, has reinvigorated Russia's efforts to complete the International North-South Transport Corridor (INSTC). This corridor holds significant potential for Russia to expand its reach to India, the Persian Gulf, and East Africa. Additionally, it is believed that the project may facilitate India's connectivity with countries in the Caucasus, Central Asia, and Eastern Europe. Therefore, this paper particularly examines the case of the land corridor, exploring its current progress in implementation, the geoeconomic factors involved, existing challenges, and opportunities for compatibility with other initiatives, such as the Europe-Caucasus-Asia Transport Corridor (TRACECA), the Belt and Road Initiative (BRI), and the Chabahar port.The author argues that, although the implementation of connectivity projects between the two countries will not solve structural problems in their trade relationship, both have a vested interest in promoting infrastructure development for a deeper engagement with new regions. To qualitatively boost Russian-Indian trade, affordable logistical solutions should be developed simultaneously with the resolution of other issues like the settlements for financial transactions, and the elimination of tariff and non-tariff barriers.
Analisis Peramalan Penerimaan Negara Bukan Pajak Menggunakan Metode Grey-Markov Dan ANFIS
Authors: Manuaba I Dewa Nyoman Anom , Sudarma Made , Gunantara Nyoman 
Published: June 2023

Universitas Udayana setiap tahunnya melaporkan Target Penerimaan Negara Bukan Pajak (TPNBP) sebagai acuan pemberian alokasi anggaran tahun T+2. Ketepatan dalam penentuan TPNBP akan berpengaruh kepada pemberian alokasi anggaran tahun T+2, sehingga dapat meningkatkan optimalisasi dalam melakukan perencanaan anggaran. Keterbatasan data realisasi PNBP di Universitas Udayana dan keunggulan metode ANFIS dalam melakukan peramalan pada tipe data stasioner, memungkinkan peramalan dengan metode Grey-Markov dan ANFIS menghasilkan peramalan yang akurat, untuk itu perlu dibandingkan metode mana yang lebih baik. Hasil dari penelitian ini menunjukan metode Grey-Markov mendapatkan nilai 0,118% sedangkan metode ANFIS mendapatkan nilai 4,978% yang artinya walaupun sama-sama mendapatkan hasil sangat akurat, tetapi metode Grey-Markov mendapatkan nilai MAPE yang lebih kecil yang berarti lebih akurat dibandingkan dengan metode ANFIS. Pada variabel penerimaan SPI, metode Grey-Markov mendapatkan hasil yang sangat akurat dengan nilai MAPE 0,319% sedangkan metode ANFIS mendapatkan hasil yang kurang akurat dengan nilai MAPE 23,39% yang berarti bahwa metode Grey-Markov lebih baik dalam melakukan peramalan penerimaan SPI.
Kata Kunci — ANFIS; Grey-Markov; Forecasting; PNBP
Rancang Bangun Sistem Pemantauan Panel Surya Berbasis Internet of Things
Authors: Kurniawan Gede Widi , Agung I G A Putu Raka , Rahardjo Pratolo 
Published: June 2023

Penerapan internet of things mulai banyak dimanfaatkan saat ini. Salah satu perkembangan teknologi internet of things adalah memantau suatu sistem dengan aplikasi android secara wireless. Penelitian ini bertujuan untuk merancang dan membangun sistem pemantauan panel surya berbasis Internet of things dengan menggunakan developer board NodeMCU ESP32. Rancangan sistem ini dapat mempermudah pengguna memantau panel surya secara realtime melalui aplikasi android. Pengujian dilakukan dengan mengoperasikan sistem pemantauan panel surya. Data dari masing-masing sensor dibandingkan dengan alat ukur pembanding untuk mendapatkan perbedaan nilai-nilainya. Hasil pengujian sensor INA219 mendapatkan selisih rata-rata tegangan 0.09% dan selisih ratarata arus 4.08%.. Hasil pengujian sensor DHT11 mendapatkan selisih rata-rata suhu 0.77% dan selisih kelembapan relatif 1.82%. Hasil pengujian sensor BH1750 mendapatkan selisih rata-rata intensitas cahaya 39.93%. Sistem pemantauan ini sudah dapat beroperasi sesuai dengan rancangan dan pembacaan data dari sensor-sensor sudah terkirim menuju Firebase sehingga bisa dilihat pada aplikasi android.
Kata Kunci— Panel Surya; Internet of Things; Android; DHT11; INA219; BH1750; ESP32.
Monitoring Tegangan dan Arus Pada Panel Surya Menggunakan IoT
Authors: Sutikno Tole , Alfahri Jekson , Purnama Hendril Satrian 
Published: June 2023

Teknologi solar panel menjadi salah satu teknologi yang sangat potensial untuk memanen energi matahari, terutama di negara tropis seperti Indonesia. Saat ini, teknologi pemanen energi berbasis panel surya/photovoltaic (PV) sudah mencapai tahap yang advance dan banyak diaplikasikan di berbagai macam kebutuhan. Di sisi lain, dengan masifnya jumlah pembangkit listrik tenaga surya (PLTS) berbasis PV, menyebabkan proses pemeliharaannya menjadi semakin sulit. Oleh karena itu dibutuhkan solusi yang dapat mengefisiensi proses pemeliharaan ini. Dengan teknologi Internet of Things (IoT) kita dapat memantau kondisi kesehatan PLTS secara daring dan real-time. Penelitian ini menggunakan mikrokontroler NodeMCU ESP8266 dan sensor INA219 untuk pemantauan arus dan tegangan pada PLTS, kemudian data tersebut akan dikirimkan via internet ke aplikasi Blynk. Metode penelitian yang dilakukan adalah dengan pengambilan data setiap 10 menit sekali pada pagi hari, siang hari, dan sore hari. Hasil penelitian menunjukkan bahwa penggunaan mikrokontroler NodeMCU ESP8266 dan platform IoT Blynk untuk aplikasi monitoring arus dan tegangan panel surya dapat menurunkan biaya produksi dengan hasil pengukuran dan pemantauan yang optimal dan stabil.
Kata Kunci— Blynk; Internet of Things; Monitoring; NodeMCU; Solar Panel.