bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of dietary crude protein levels in the concentrate supplement after grazing on rumen microbiota and metabolites by using metagenomics and metabolomics in Jersey-yak
Authors: Dai Rongfeng , Ma Xiaoming , Dingkao Renqing , Huang Chun , La Yongfu , Li Xinyi , Ma Xiaoyong , Wu Xiaoyun , Chu Min , Guo Xian , Pei Jie , Yan Ping , Liang Chunnian 
Published: May 2023

IntroductionThe crude protein level in the diet will affect the fermentation parameters, microflora, and metabolites in the rumen of ruminants. It is of great significance to study the effect of crude protein levels in supplementary diet on microbial community and metabolites for improving animal growth performance. At present, the effects of crude protein level in supplementary diet on rumen fermentation parameters, microbial community, and metabolites of Jersey-Yak (JY) are still unclear.MethodsThe purpose of this experiment was to study the appropriate crude protein level in the diet of JY. The rumen fermentation indexes (volatile fatty acids and pH) were determined by supplementary diets with crude protein levels of 15.16 and 17.90%, respectively, and the microbial community and metabolites of JYs were analyzed by non-target metabonomics and metagenome sequencing technology, and the changes of rumen fermentation parameters, microbial flora, and metabolites in the three groups and their interactions were studied.Results and DiscussionThe crude protein level in the supplementary diet had significant effects on pH, valeric acid, and the ratio of acetic acid to propionic acid (p &lt; 0.05). The protein level had no significant effect on the dominant microflora at the phylum level (p &gt; 0.05), and all three groups were Bacteroides and Firmicutes. The results of metabolite analysis showed that the crude protein level of supplementary diet significantly affected the metabolic pathways such as Bile secretion and styrene degradation (p &lt; 0.05), and there were different metabolites between the LP group and HP group, and these different metabolites were related to the dominant microbial to some extent. To sum up, in this experiment, the effects of crude protein level in supplementary diet on rumen microorganisms and metabolites of JY and their relationship were studied, which provided the theoretical basis for formulating a more scientific and reasonable supplementary diet in the future.
Analysis of phenolic compounds in Parkinson’s disease: a bibliometric assessment of the 100 most cited papers
Authors: Perdigão José Messias , Teixeira Bruno José Brito , Baia-da-Silva Daiane Claydes , Nascimento Priscila Cunha , Lima Rafael Rodrigues , Rogez Herve 
Published: May 2023

ObjectiveThe aim of this study was to identify and characterize the 100 most cited articles on Parkinson’s disease (PD) and phenolic compounds (PCs).MethodsArticles were selected in the Web of Science Core Collection up to June 2022 based on predetermined inclusion criteria, and the following bibliometric parameters were extracted: the number of citations, title, keywords, authors, year, study design, tested PC and therapeutic target. MapChart was used to create worldwide networks, and VOSviewer software was used to create bibliometric networks. Descriptive statistical analysis was used to identify the most researched PCs and therapeutic targets in PD.ResultsThe most cited article was also the oldest. The most recent article was published in 2020. Asia and China were the continent and the country with the most articles in the list (55 and 29%, respectively). In vitro studies were the most common experimental designs among the 100 most cited articles (46%). The most evaluated PC was epigallocatechin. Oxidative stress was the most studied therapeutic target.ConclusionDespite the demonstrations in laboratorial studies, the results obtained point to the need for clinical studies to better elucidate this association.
Automatic facial coding predicts self-report of emotion, advertisement and brand effects elicited by video commercials
Authors: Höfling T. Tim A. , Alpers Georg W. 
Published: May 2023

IntroductionConsumers’ emotional responses are the prime target for marketing commercials. Facial expressions provide information about a person’s emotional state and technological advances have enabled machines to automatically decode them.MethodWith automatic facial coding we investigated the relationships between facial movements (i.e., action unit activity) and self-report of commercials advertisement emotion, advertisement and brand effects. Therefore, we recorded and analyzed the facial responses of 219 participants while they watched a broad array of video commercials.ResultsFacial expressions significantly predicted self-report of emotion as well as advertisement and brand effects. Interestingly, facial expressions had incremental value beyond self-report of emotion in the prediction of advertisement and brand effects. Hence, automatic facial coding appears to be useful as a non-verbal quantification of advertisement effects beyond self-report.DiscussionThis is the first study to measure a broad spectrum of automatically scored facial responses to video commercials. Automatic facial coding is a promising non-invasive and non-verbal method to measure emotional responses in marketing.
Effects of Adriamycin-Cytoxan chemotherapy on hematological and electrolyte parameters among breast cancer patients
Authors: Tadesse Fikremariam Abiye , Leminie Abebaye Aragaw 
Published: May 2023

BackgroundAdriamycin-Cytoxan (AC) is a common chemotherapy treatment for breast cancer (BC) patients. Its electrolyte and hematological adverse effects have not been addressed adequately.ObjectiveThis study aimed to assess the effect of AC on hematological and electrolyte parameters among BC patients.MethodsA hospital-based comparative cross-sectional study design was conducted from March to November 2022. Randomly selected AC-treated (n=100) and untreated (n=100) patients were included. Structured questionnaire and medical records were used to collect sociodemographic data. Anthropometric parameters, hematological indices, and serum electrolytes were measured. Cobas Integra 400+and SYSMEX-XT-4000i were used to analyze serum electrolytes and hematological indices respectively. The data were analyzed using SPSS version 25. Independent t-test and chi-square test were used. p-value &lt;0.05 was considered statistically significant.ResultsAC-treated patients’ mean total white blood cell (TWBC), neutrophil (NE), lymphocyte (LY), red blood cell (RBC), hemoglobin (Hgb), hematocrit (HCT), and sodium(Na+) values were significantly reduced (p&lt;0.05) than patients with no treatment. However, mean eosinophils (EO), platelet (PLT) counts, red cell distribution-width (RDW), potassium (K+), and plateletcrit (PCT values were significantly increased (p&lt;0.05).ConclusionThe majority of blood cells and serum sodium were affected by AC treatment. Incorporating these parameters in the routine analysis and further studies on the detailed mechanism of action of this drug is required.
Juvenile dermatomyositis and nephrotic syndrome: A case report and a mini literature review
Authors: Zhou Weiran , Dong Linlin , Liu Xuemei , Dong Chunhua , Zhang Hongxia 
Published: May 2023

BackgroundRenal involvement is rarely reported in juvenile dermatomyositis and may be caused by the toxic effects of myoglobinuria or an autoimmune reaction. We report a case of dermatomyositis and nephrotic syndrome in a child to explore the association between juvenile dermatomyositis and renal involvement.Case presentationAn 8-year-old girl with skin rash, edema, proximal muscle weakness predominantly involving the lower extremities, low-grade fever, and foamy urine was admitted to our hospital. Her laboratory tests met the criteria of nephrotic syndrome. She had elevated creatine kinase and lactate dehydrogenase and was diagnosed with juvenile dermatomyositis after electromyography and muscle MRI. Anti-NXP2 antibodies were positive. Her proteinuria was relieved soon after treatment with prednisone and methotrexate, but her muscle strength progressively decreased. The disease was relieved after pulse methylprednisolone treatment and mycophenolate mofetil, but recurred after drug reduction with mild proteinuria. Adalimumab was used for treatment and helped reduce the doses of glucocorticoid and mycophenolate mofetil.ConclusionJuvenile dermatomyositis may be one of the rare causes of nephrotic syndrome. The mechanism involved in JDM combined with renal injury may be multifactorial. Autoantibodies may play important roles in both muscle and renal damage.
Monolithically integrated laser with DBR for wideband and low time delay signature chaos generation
Authors: Li Shuhui , Qiao Lijun , Chai Mengmeng , Zhang Mingjiang 
Published: May 2023

Chaotic laser has attracted a large amount of attention due to its broad spectrum, noise-like characteristics, and photonic integrated chaotic semiconductor lasers have further expanded the application field of chaotic laser for their small size and stable properties. Therefore, a monolithically integrated laser with a distributed Bragg reflector (DBR) is designed. This proposed chaotic laser consists of a distributed feedback (DFB) laser section, a phase section, and a DBR section. DBR grating can provide wavelength detuning to generate mode beating, which enhances chaotic bandwidth and distributed feedback to suppress time delay signature (TDS). The transmission line laser model (TLLM) of chaotic laser is constructed and chaotic characteristics of the integrated chip are investigated. A chaotic signal with a bandwidth of 12.34 GHz and TDS less than 0.065 is obtained. In addition, a map of dynamic states in the parameter space of phase section current and DBR section current is shown, and a wide range of chaotic regions are obtained. The results show that the broadband chaotic laser with a low TDS can be obtained by controlling the parameters reasonably, which is beneficial to realize the application of chaotic laser.
Process-outcome relations in music therapy versus music listening for people with schizophrenia viewed through a mediational model: the role of the therapeutic alliance
Authors: Hannibal Niels , Pedersen Inge Nygaard , Bertelsen Lars Rye , Nielsen René Ernst , Gold Christian 
Published: May 2023

ObjectivesExamine whether change in clinical outcomes for patients with schizophrenia and negative symptoms randomized to either Music Therapy (MT) or Music Listening (ML) is associated to moderators and mediators, with focus on alliance, attendance and dropout.MethodAn exploratory post-hoc analysis of data from an original randomized controlled trial (RCT) investigating the effect of MT vs. ML for people with schizophrenia and negative symptoms. Inclusion to the study was implemented through screening of referred patients for symptoms of schizophrenia and negative symptoms. A total of 57 patients were randomly assigned, 28 to MT and 29 to ML. Session logs and notes were included in this study. Statistical analysis investigated moderator and mediator relation to outcome variables: Negative symptoms, functioning, quality of life, and retention to treatment.ResultsOn average, participants in MT attended 18.86 sessions (SD = 7.17), whereas those in ML attended 12.26 (SD = 9.52), a statistically significant difference (p = 0.0078). Dropout at 25 weeks was predicted by intervention, with dropout being 2.65 (SE = 1.01) times more likely in ML than in music therapy (p = 0.009). Helping alliance score at weeks was explained by intervention, with mean score being 0.68 (SE = 0.32) points lower in ML than in MT (p = 0.042). The number of sessions attended was also explained by intervention, with participants in ML attending on average 6.17 (SE = 2.24) fewer sessions than those randomized to MT (p = 0.008). Though both groups improved significantly, improvements in negative symptoms, depression, and functioning tended to be higher in ML, whereas improvements in alliance and quality of life tended to be higher in MT.ConclusionThe analysis could not detect a direct link between helping alliance score and outcome variables. However, the analysis documented a stronger alliance developed in the MT group, a lower dropout rate, as well as higher attendance in treatment.Clinical Trial Registration: www.ClinicalTrials.gov, identifier: NCT02942459.
Program evaluation of a virtual physical activity program for individuals with disabilities
Authors: Matthews Nikki , Seaman Roxanne , Bremer Emily 
Published: May 2023

IntroductionRegular physical activity is important for positive health outcomes yet, most individuals do not meet physical activity guidelines. Recent studies show that one in five Canadians aged 15 or older have one or more disabilities, yet as a population, individuals with disabilities are 16%–62% less likely to meet physical activity guidelines. The COVID-19 pandemic created additional barriers to physical activity participation as lockdowns prevented in-person programming. In response to the pandemic, the Acadia University Sensory Motor Instructional Leadership Experience (S.M.I.L.E.) Program shifted its programming to a virtual platform; however, there was little research to guide its creation, implementation, or expected outcomes. Thus, this program evaluation explored program feasibility and impact on physical activity and physical literacy.MethodA mixed methods case study approach was used for this project. Virtual S.M.I.L.E. took place over eight weeks in the fall of 2020. Programming consisted of three live Zoom sessions facilitated by trained program leaders, and eight weeks of at-home activity guides for participants to complete on their own time. Demographic data, physical literacy (PLAYself), and physical activity (IPAQ-A) data were collected using caregiver pre-and post-programming surveys. Throughout programming, weekly check-in surveys were sent to reflect on the previous week of programming. After the eight weeks of programming were complete, caregiver and leader interviews were conducted to understand both program implementation and performance perspectives.ResultsResults indicated that participants' (N = 15, Mage = 20.4 years) overall physical literacy and physical activity did not change; however, there was a decrease in the cognitive domain of physical literacy (p = 0.03). Caregiver and leader interviews highlighted five main themes following the virtual programming: (a) Virtual impact on programming; (b) Programming impact on social and motor goals; (c) Impact of program design; (d) Impact on physical activity; and (e) Program feasibility for families.DiscussionResults from this program evaluation suggest that physical literacy and physical activity levels were generally maintained throughout programming and caregivers indicated several social and activity benefits. Future work includes program modifications and further evaluation of virtual adapted physical activity programming to improve the physical literacy of individuals with disabilities.
Sabão artesanal no espaço escolar como ferramenta de sensibilização ambiental
Authors: Lopes Marília de Oliveira , Pimenta Daniel Sales , Conde Bruno Esteves 
Published: May 2023

Problemas ambientais e suas consequências estão interligados e influenciam todas as esferas do meio biológico e do nosso cotidiano, sendo um dos assuntos mais abordados dentro da disciplina de Biologia em que o uso de novas abordagem na maneira de trabalhar Educação Ambiental é justificável, pois é assunto urgente e necessário devido a degradação ambiental que o planeta vem sofrendo. Muito mais do que ensinar conceitos, é preciso tornar o aluno um participante efetivo e ativo na prática de conservação do meio ambiente. Diante do exposto, o presente estudo avaliou o engajamento de alunos do Ensino Médio, de uma escola pública no interior do estado do Rio de Janeiro, sobre a problemática ambiental, a partir da vivência prática na produção de sabão reciclado de óleo de cozinha usado, em que os alunos foram os protagonistas de cada etapa da sequência didática, inclusive na coleta do óleo, que rendeu uma enorme quantidade de produto arrecadado. A metodologia contou com uma sequência didática desenvolvida no decorrer do ano letivo, contando ainda com palestras, pesquisas, produção de material expositivo e aplicação de questionário. Este último, sendo aplicado antes e após as intervenções, permitindo verificação quantitativa com respostas comparadas através de análise estatística. Foi possível constatar como positiva a participação dos alunos, observando-se uma postura diferenciada destes diante do objeto de estudo, interesse durante palestras de sensibilização e pensamento crítico perante as descobertas dos impactos negativos do homem no ambiente natural, reforçando a potencialidade desse método para aumentar a sensibilização ambiental nos adolescentes, bem como reforçar o propósito da escola de educar para a cidadania. A proposta mostrou-se uma alternativa viável, adaptável ao cronograma escolar e de amplo alcance. Concluindo-se, ainda, que a sequência didática utilizada é passível de ser replicada em outras escolas.
Evaluation of hypervelocity impact of micrometeoroids and orbital debris on next-generation space solar cells
Authors: Toyota Hiroyuki , Nakamura Tetsuya , Kanaya Shusaku , Sumita Taishi , Hirai Takayuki , Kobayashi Masanori 
Published: May 2023

Abstract
This paper discusses the hypervelocity impacts of micrometeoroids and orbital debris (MMODs) on inverted metamorphic triple-junction (IMM3J) and perovskite solar cells, which are much thinner than conventional triple-junction (3J) solar cells. We experimentally found that IMM3J solar cells can suffer from short-circuit faults due to the hypervelocity impacts of MMODs, unlike conventional 3J cells, and determined the projectile diameters and velocities that could cause them using a model proposed by Burt. No short-circuit mode was identified in perovskite solar cells, but they had open-circuit faults several days after the hypervelocity impact experiment, which are possibly attributed to the decomposition of the perovskite crystal by moisture in the air due to the broken seal.
أسس بناء الشخصية في الدراما التلفزيونية العراقية
Authors: م.م. سلوان بهاء كاظم موسى  
Published: May 2023

تعد الشخصية محورا اساسياً تستند اليها الدراما بوصفها الرافد الذي ينتقل عنطريقها الحدث والصراع الدرامي؛ كما واخذت الشخصية مركز الصدارة في الدراساتالنفسية والاجتماعية ودراسات الادب والدراما. فضلا على ان الشخصية هي احدى القيمالدراماتيكية التي يستند عليها صانع العمل الفني في عملية توظيفها داخل المنجز المرئي.مع بقية عناصر البناء الدرامي لكي تكون بمثابة نقطة الارتكاز في بناء الحدث ولذلك نجدان صانع العمل الدرامي يولي اهتمام كبير في تفسيره للشخصية الدرامية وفق معالجة بناءالشخصية الدرامية وتفاعلها مع بقية العناصر وفق رؤية تتسم بالتجديد في بناء الشخصيةالدرامية داخل المنجز المرئي ولذلك فان العديد من التفسيرات قد وضعت لفهم مكوناتالشخصية الدرامية وبنائها داخل المنجز المرئي.مشكلة البحث والحاجة الية: شهدت الدراما التلفزيونية العراقية تطورا واسعا في المجالين التقني والفني ؛اذاصبحت حقلا يجاور المفاهيم العلمية والتقنية الحاليةءوليس على المستوى المعالجةالاخراجية فحسب ذفقد خضعت الكتابة الجديدة للسيناريو التلفزيووني الى انفتاحات متعددةتمخضت عنها الكثير من التجارب الجديد ءوقد شكلت الشخصية في الدراما التلفزيونيةالمعاصرة محورا" فاعلا في عمليات بناء الصورة المرئية والمسموعة عبر تمركزها فيالفعل الدرامي المؤثر على المتلقي؛ من خلال تحولاتها ونموها وتطورها المستمر ‎٠‏‏فافعالها وسلوكها هي التي تولد الانطباع عنها ومن خلا لها تصبح فاعلة ومؤثرة فيغايتها التي تسعى الى تحقيقها فالشخصية تبنى من خلال تأصر مجموعة من الاسسالدرامية والاجتماعية والسايكولوجية من جهةءوطرق معالجتها التلفزيونية من جهة
تنمية القوة العضلية والكثافة العظمية باستخدام تدريبات المطاط واثرها على مستوى اداء بعض المهارات الاساسية بالكرة الطائرة
Authors: ا.م. د سهاد قاسم سعيد الموسوي  
Published: May 2023

ان اساس الارتقاء الشامل في الالعاب الرياضيه ومنها الكرة الطائره هو الاعداد
البدني الشامل الذي يتركز باستخدام اساليب تدريبيه وتمرينات صحيحه تنسجم مع العنصر
المراد تطويره سواء كان بدنيا ام مهاريا على ان يكون دقيقا في تهيئه الاسلوب والطريقه
المناسبه لنوع الرياضه التي يدربها والعنصر البدني الذي يطورهكان هدف البحث التعرف
على تاثير تدريبات المطاط لتنمية القوه العضليه والكثافه العظميه للاعبي الناشئين بالكرة
الطائرة ومن فروض البحث هي وجود فروق معنويه بين الاختبارات القبليه والبعديه لدى
المجموعه التجريبيه والضابطه بتاثير تدريبات المطاط شمات مجتمع البحث من لاعبي
الشباب بالكرة الطائره والبالغ عددهم (٩١)لاعبا‏ وقد اجريت التجربه الرئسيه يتاريخ
‎٠١٠5‏ ولغايه ٢٢/٨/٤١٠٢وتم‏ استخدام المنهج التجريبي لملاءمته لطبيعة البحث
وبعد استخدام المعالجات الاحصائيه نوصلت الباحثه :الى مادة كفاءة العظام للمجموعه
التجريبيه بشكل افضل عند مقارنتها بالمجموعة الضابطة ممايؤكد فعاليه المجموعه
التجريبيه بتاثير المنهاج التجريبي وتوصلت الباحثه الى ضرور التركيز والتاكيد على
الاهتمام بتدريبات المطاط لما لها من تاثير ايجابي في تنمية القوة العضليه والكثافة
العظمية
Synthesis of N-Substituted 3-Chloro- 2-azetidinones for 2, 4-diamino-6- hydroxy pyrimidin
Authors: Amal S. Sadiq  
Published: May 2023

This search involved synthesis of several new N-Substituted -3-chloro-
2-azetidinones which were known as a high medicinal effectiveness for 2,
4-Diamino-6-hydroxy pyrimidin in two steps. The first step included
preparation Shiff bases (1-6) by condensation of 2, 4-Diamino-6-hydroxy
pyrimidin with many substituted aldehydes(4-hydroxy benzaldehyde, 2-
bromobenzaldehyde, 4-dimethyl amino benzaldehyde, = 4-nitro
benzaldehyde, salicylaldehyde, 4-chlorobenzaldehyde), then the second
step included, preparation new six azetidinones compounds (7-12) by
reaction of chloroacetylchloride with the prepared Schiff bases in the first
step in the presence of triethylamine. The structures of synthesized
compounds were- characterized by physical properties (FT-IR, UV and
some of them by 'H-NMR, C_NMR spectroscopy) were recorded.
The Cyber Centre, Host and Cloud-Based Sensor Technology - An Analysis
Authors: Ahmed Ashar 
Published: May 2023

<p>The emerging cybersecurity industry in Canada is not seen as anywhere near the scale of its American cyber-industrial complex counterpart, with limited-scale projects occurring to improve security sensor technology for institutions. However, due to international trade increasingly occurring through cyberspace, it is expected that the cyber industry will grow in Canada through both international and domestic partnerships, with Canadian critical infrastructure partners requiring greater security controls in order to ensure the confidentiality, integrity and availability of their data and operations. </p>
Bringing To Light: Adversarial Poisoning Detection in Multi-controller Software-defined Networks
Authors: Das Tapadhir , Shukla Raj , Rath Suman , Sengupta Shamik 
Published: May 2023

<p>Machine learning (ML)-based network intrusion detection systems (NIDS) have become a contemporary approach to efficiently protect network communications from cyber attacks. However, ML models can become exploited by adversarial poisonings, like random label manipulation (RLM), which can compromise multi-controller software-defined network (MSDN) operations. In this paper, we develop the Trans-controller Adversarial Perturbation Detection (TAPD) framework for NIDS in multi-controller SDN setups. The detection framework takes advantage of the SDN architecture and focuses on the periodic transference of network intrusion detection models across the SDN controllers in the topology, and validates the models using the local datasets to calculate errors in their predictions with the ground truth. We demonstrate the efficacy of this framework in detecting RLM attacks in an MSDN setup. Results indicate efficient detection performance achieved by the TAPD framework in determining the presence of Random Label Manipulation attacks and the localization of the compromised controllers. We find that the framework works well even when there is a significant number of compromised agents in a large multi-controller setting. However, the performance begins to deteriorate when more than 40% of the SDN controllers in the MSDN have become compromised. </p>