bluuebunny/crossref_metadata_2025_split huggingface dataset:
Indolent adult T‐cell leukaemia‐lymphoma successfully treated with bexarotene in an eldery patient
Authors: Nakashima Maho , Takenaka Motoi , Murota Hiroyuki 
Published: May 2023

AbstractAdult T‐cell leukaemia‐lymphoma (ATL) is a mature T‐cell malignancy, with more than 50% of cases showing cutaneous involvement. Patients with cutaneous‐type ATL (cATL) in the indolent type (i.e., favourable chronic or smouldering type) can usually be managed by watchful waiting and they are primarily treated with skin‐directed therapies until the disease progresses to acute crisis, with multiple tumours usually considered intractable. ATL tends to present in older patients, and those with multiple cATL tumours face difficulties in obtaining multiagent chemotherapy used for aggressive types. Although bexarotene is a third‐generation novel retinoid X receptor‐selective retinoid treatment that is effective for cutaneous T‐cell lymphoma, few reports have demonstrated its effectiveness for cATL. We describe an 86‐year‐old woman with cATL treated safely and successfully with a combination of oral bexarotene and skin‐directed therapies, despite renal dysfunction and previous hypothyroidism. After 10 months of treatment, we observed neither new tumours nor disease recurrence, with complete response maintained at 24 months until now while continuing bexarotene. Our experience suggests that oral bexarotene is an effective treatment option, even for elderly patients with cATL.
The universal commensurability Busemann horofunction compactified Teichmüller space
Authors: Hu Guangming , Lv Zhiyang , Miyachi Hideki , Qi Yi , Tan Dong 
Published: May 2023

AbstractIn this paper, the direct limit of Busemann horofunction compactified Teichmülller spaces is introduced. It is shown that the action of the universal commensurability modular group on is isometric and for any point in the universal commensurability Teichmüller space , its orbit under this action is dense in . Furthermore, we construct the direct limit of Busemann horofunction compactified moduli spaces by the characteristic towers and show that the subgroup of acts on to produce as the quotient. Finally, we get a formula of the limit distance between two Jenkins–Strebel rays in the universal commensurability Teichmüller space.
Evaluating satisfaction with teaching innovation, its relationship to academic performance and the application of a video‐based microlearning
Authors: Román‐Sánchez Daniel , De‐La‐Fuente‐Rodríguez José Manuel , Paramio Alberto , Paramio‐Cuevas Juan Carlos , Lepiani‐Díaz Isabel , López‐Millan María‐Reyes 
Published: May 2023

AbstractAimTo develop and validate a questionnaire to assess satisfaction with teaching innovation, assess the student satisfaction with a video‐based microlearning intervention in its video‐based modality and to verify its impact on academic performance.DesignA descriptive cross‐sectional study was conducted. The study used the COSMIN checklist for studies on measurement instruments.MethodsOne hundred and ten nursing students from Salus Infirmorum University Centre (Andalusia, Spain) participated in the study. The items of the instrument were designed based on a literature review and its validity and stability were analysed. After that, 6 weeks of video‐based microlearning intervention were implemented. Then students were asked to fill the satisfaction questionnaire and then took the subject exam.ResultsThe resulting questionnaire consisted of 5 items with only one dimension. The questionnaire showed good validity and reliability. A direct correlation was observed between satisfaction with the video‐based microlearning intervention and the marks of the subject exam.
Sealing characteristics of aramid fiber reinforced rubber gasket with scratch depth and width defects
Authors: Zhang Bin , Jin Xiang , Yu Tao , Yu Xiaoming , Yang Cheng 
Published: May 2023

AbstractNon‐asbestos gaskets have high tensile properties, good permeability resistance, and resilience. Compared with traditional asbestos gaskets, non‐asbestos gaskets have the advantages of less pollution and no harm to human body. This manuscript presented an experimental and theoretical study of aramid fiber reinforced non‐asbestos gaskets. The tensile strength of gaskets with different fiber orientations and tensile rate were conducted in order to meet the industrial standard. The leakage rates of nondestructive non‐asbestos gaskets with different sizes under different medium pressures and pretightening load were investigated. The results showed that the leakage rate can reach the industrial standard when the pretightening load reached 30 MPa and medium pressures was less than 2 MPa. The artificial scratch defects were made on non‐asbestos gaskets, and the effect of the width and depth of the scratch defect on leakage rate was further investigated. The sealing failure would occur when the scratch depth reached 0.1 mm. The modified model containing defect factors was established. The results showed that the modified model can well characterize leakage rate of gasket.
Poverty, entrepreneurship, and economic growth in Africa
Authors: Ajide Folorunsho M. , Dada James T. 
Published: May 2023

AbstractLiterature abounds on the impact of entrepreneurship on economic growth, but with little attention to the role of entrepreneurship in poverty reduction. Furthermore, little attention has been paid to the triangular relationship among poverty reduction, entrepreneurship, and growth in Africa. In this study, we examine the dynamic relationship among these three variables using data collected from 18 African countries. Data are sourced from World Bank development indicators and the World Bank's entrepreneurship database. The study uses batteries of panel data estimation techniques to analyze the data. The following findings emerged: (1) there is bidirectional causality between poverty reduction and growth. (2) There is bidirectional causality between growth and entrepreneurship in Africa. (3) There is unidirectional causality moving from entrepreneurship to poverty reduction. (4) Entrepreneurship significantly reduces poverty in Africa. (5) Impulse response shows that all the variables positively respond to shocks in each other. The study concludes that entrepreneurship enhances poverty reduction in Africa and has a significant impact on economic growth.
Advancements in imaging in ChILD
Authors: Spielberg David R. , Weinman Jason , DeBoer Emily M. 
Published: May 2023

AbstractInterstitial and diffuse lung diseases in children constitute a range of congenital and acquired disorders. These disorders present with signs and symptoms of respiratory disease accompanied by diffuse radiographic changes. In many cases, radiographic findings are nonspecific, while in other disorders, chest computed tomography (CT) is diagnostic in the appropriate context. Regardless, chest imaging remains central in the evaluation of the patient with suspected childhood interstitial lung disease (chILD). Several newly described chILD entities, spanning both genetic and acquired etiologies, have imaging that aid in their diagnoses. Advances in CT scanning technology and CT analysis techniques continue to improve scan quality as well as expand use of chest CT as a research tool. Finally, ongoing research is expanding use of imaging modalities without ionizing radiation. Magnetic resonance imaging is being applied to investigate pulmonary structure and function, and ultrasound of the lung and pleura is a novel technique with an emerging role in chILD disorders. This review describes the current state of imaging in chILD including recently described diagnoses, advances in conventional imaging techniques and applications, and evolving new imaging modalities that expand the clinical and research roles for imaging in these disorders.
Oral antibiotics lower mycophenolate mofetil drug exposure, possibly by interfering with the enterohepatic recirculation: A case series
Authors: Simoons Mirjam , Naipal Kishan A. T. , de Jong Huib , den Hoed Caroline M. , de Winter Brenda C. M. , Mulder Midas B. 
Published: May 2023

AbstractMycophenolate mofetil has an important role as immunosuppressive agent in solid organ transplant recipients. Exposure to the active mycophenolic acid (MPA) can be monitored using therapeutic drug monitoring. We present three cases in which MPA exposure severely decreased after oral antibiotic coadministration. By diminishing gut bacteria β‐glucuronidase activity, oral antibiotics can prevent deglucuronidation of the inactive MPA‐7‐O‐glucuronide metabolite to MPA and thereby possibly prevent its enterohepatic recirculation. This pharmacokinetic interaction could result in rejection, which makes it clinically relevant in solid organ transplant recipients, especially when therapeutic drug monitoring frequency is low. Routine screening for this interaction, preferably supported by clinical decision support systems, and pragmatic close monitoring of the MPA exposure in cases is advised.
Unique times, unequal mobilities: Daily mobility during the de‐escalation of the COVID‐19 pandemic
Authors: Padilla‐Pozo Álvaro , Torrado José Manuel , Palomares‐Linares Isabel , Duque‐Calvache Ricardo 
Published: May 2023

AbstractScholars have highlighted drastic reductions in daily mobility during the early stages of the COVID‐19 pandemic lockdown. But what happened when restrictions were relaxed though risk remained ubiquitous? How did patterns of mobility change and how were they structured by socioeconomic resources and social roles? We address these questions using a cross‐sectional representative sample (n = 2942) of the population of Andalusia, Spain, after a month and a half of severe lockdown in 2020. We find that older people were the least mobile group and that people living with children and in extended households were less likely to move to take care of others, unlike before the pandemic. Men were more likely to carry out daily mobilities for which women had been traditionally responsible, such as care mobilities. Women were also more likely to be immobile and less likely to commute. Finally, manual and nonqualified workers were more likely to commute, but they were just as likely as any other group to carry out other types of mobility. These results highlight the social character of mobility in a unique context. We emphasize the need to disaggregate daily mobility based on different purposes as well analysing how these are practised by different sociodemographic groups if we want to provide rigorous descriptions of a core component of individuals’ daily life.
Emotional configurations in STEM classrooms: Braiding feelings, sensemaking, and practices in extended investigations
Authors: Pierson Ashlyn E. , Brady Corey E. , Lee Sarah J. 
Published: May 2023

AbstractAttending to emotion in science classrooms can expand the range of resources valued for science learning, and it can offer insights into students' investigations. However, research that characterizes emotion as a part of disciplinary science learning is relatively nascent. In response, we explore the dynamic relationships between feelings, sensemaking, and practices in a sixth‐grade STEM classroom, guided by (a) Kimmerer's (2013) account of braiding Eurocentric disciplinary science with other resources, including feelings, and (b) Vea's (2020) framework of emotional configurations. We analyze data from multiple iterations of a 9‐week curriculum about guppies' survival needs and the dynamics of ecosystems, illustrating how students' feelings and their sensemaking through practices involving observation were intertwined in generative and mutually‐reinforcing ways. First, we show how the teacher and researcher made space for students to express feelings, in part in response to a student who used feelings to challenge “business as usual” classroom discourse on a day when guppies were discovered to have died. Then, we show how, in subsequent implementations, feelings, sensemaking, and practices were braided together to shape classroom investigations. We argue that attending to feelings in this way, as valued resources to be integrated with sensemaking and practices, is an important step toward equitable science teaching and learning and toward understanding learning in student‐driven contexts.
Dual Atoms (Fe, F) Co‐Doping Inducing Electronic Structure Modulation of NiO Hollow Flower‐Spheres for Enhanced Oxygen Evolution/Sulfion Oxidation Reaction Performance
Authors: Lyu Chaojie , Li Yanle , Cheng Jiarun , Yang Yuquan , Wu Kaili , Wu Jiwen , Wang Huichao , Lau Woon‐Ming , Tian Ziqi , Wang Ning , Zheng Jinlong 
Published: May 2023

AbstractHeteroatoms Fe, F co‐doped NiO hollow spheres (Fe, F‐NiO) are designed, which simultaneously integrate promoted thermodynamics by electronic structure modulation with boosted reaction kinetics by nano‐architectonics. Benefiting from the electronic structure co‐regulation of Ni sites by introducing Fe and F atoms in NiO , as the rate‐determined step (RDS), the Gibbs free energy of OH* intermediates (ΔGOH*) for Fe, F‐NiO catalyst is significantly decreased to 1.87 eV for oxygen evolution reaction (OER) compared with pristine NiO (2.23 eV), which reduces the energy barrier and improves the reaction activity. Besides, densities of states (DOS) result verifies the bandgap of Fe, F‐NiO(100) is significantly decreased compared with pristine NiO(100), which is beneficial to promote electrons transfer efficiency in electrochemical system. Profiting by the synergistic effect, the Fe, F‐NiO hollow spheres only require the overpotential of 215 mV for OER at 10 mA cm−2 and extraordinary durability under alkaline condition. The assembled Fe, F‐NiO||Fe‐Ni2P system only needs 1.51 V to reach 10 mA cm−2, also exhibits outstanding electrocatalytic durability for continuous operation. More importantly, replacing the sluggish OER by advanced sulfion oxidation reaction (SOR) not only can realize the energy saving H2 production and toxic substances degradation, but also bring additional economic benefits.
Vapor‐Phase Synthesis of Molecularly Imprinted Polymers on Nanostructured Materials at Room‐Temperature
Authors: Mazzotta Elisabetta , Di Giulio Tiziano , Mariani Stefano , Corsi Martina , Malitesta Cosimino , Barillaro Giuseppe 
Published: May 2023

AbstractMolecularly imprinted polymers (MIPs) have recently emerged as robust and versatile artificial receptors. MIP synthesis is carried out in liquid phase and optimized on planar surfaces. Application of MIPs to nanostructured materials is challenging due to diffusion‐limited transport of monomers within the nanomaterial recesses, especially when the aspect ratio is >10. Here, the room temperature vapor‐phase synthesis of MIPs in nanostructured materials is reported. The vapor phase synthesis leverages a >1000‐fold increase in the diffusion coefficient of monomers in vapor phase, compared to liquid phase, to relax diffusion‐limited transport and enable the controlled synthesis of MIPs also in nanostructures with high aspect ratio. As proof‐of‐concept application, pyrrole is used as the functional monomer thanks to its large exploitation in MIP preparation; nanostructured porous silicon oxide (PSiO2) is chosen to assess the vapor‐phase deposition of PPy‐based MIP in nanostructures with aspect ratio >100; human hemoglobin (HHb) is selected as the target molecule for the preparation of a MIP‐based PSiO2 optical sensor. High sensitivity and selectivity, low detection limit, high stability and reusability are achieved in label‐free optical detection of HHb, also in human plasma and artificial serum. The proposed vapor‐phase synthesis of MIPs is immediately transferable to other nanomaterials, transducers, and proteins.
Ultraviolet‐Assisted Printing of Flexible Solid‐State Zn‐Ion Battery with a Heterostructure Electrolyte
Authors: Bu Fan , Gao Yong , Wang Qiangzheng , Wang Yuxuan , Li Chun , Yang Jiayu , Liu Xiangye , Guan Cao 
Published: May 2023

AbstractFlexible solid‐state Zn‐ion batteries (ZIBs) have garnered considerable attention for next‐generation power sources, but the corrosion, dendrite growth, and interfacial problems severely hinder their practical applications. Herein, a high‐performance flexible solid‐state ZIB with a unique heterostructure electrolyte is facilely fabricated through ultraviolet‐assisted printing strategy. The solid polymer/hydrogel heterostructure matrix not only isolates water molecules and optimizes electric field distribution for dendrite‐free anode, but also facilitates fast and in‐depth Zn2+ transport in the cathode. The in situ ultraviolet‐assisted printing creates cross‐linked and well‐bonded interfaces between the electrodes and the electrolyte, enabling low ionic transfer resistance and high mechanical stability. As a result, the heterostructure electrolyte based ZIB outperforms single‐electrolyte based cells. It not only delivers a high capacity of 442.2 mAh g−1 with long cycling life of 900 cycles at 2 A g−1, but also maintains stable operation under mechanical bending and high‐pressure compression in a wide temperature range (−20 °C to 100 °C).
Preputial urolith deposition and urate urolith obstruction in a calf
Authors: Ozturan Yalcin Alper , Akin Ibrahim 
Published: May 2023

AbstractThis case report aimed to describe a rare case of urate urolith deposition and preputial obstruction in a 6‐month‐old calf. The owner reported that the calf was purchased from an auction 1 month ago and the calf was having difficulty urinating. The calf was depressed, and crusty painful masses were found in the prepuce. Blood urea nitrogen and serum creatinine concentrations were within reference ranges. Radiographic imaging revealed urolith deposition in the prepuce, and the preputial orifice was obstructed with a urolith. Cystocentesis was carried out and uroliths were removed using local infiltration and regional anaesthesia. The analysis of the mineral composition indicated that the uroliths' composition was uric acid. Forceps were used to carefully manipulate the urolith to remove it from the obstructed preputial orifice. The animal had a perfect recovery 1 week later.
Organised Crime in the Fisheries Sector
Authors: Witbooi Emma , Ali Kamal-Deen , Santosa Mas Achmad , Hurley Gail , Husein Yunus , Maharaj Sarika , Okafor-Yarwood Ifesinachi , Quiroz Inés Arroyo , Salas Omar 
Published: May 2023

AbstractThe fisheries sector, like most economic sectors, is impacted by organised crime. Organised crime deprives states of national revenue and threatens the legitimate fishing industry and the livelihoods of those that rely on it.
Vacuum transitions in two-dimensions and their holographic interpretation
Authors: Pasquarella Veronica , Quevedo Fernando 
Published: May 2023

Abstract
We calculate amplitudes for 2D vacuum transitions by means of the Euclidean methods of Coleman-De Luccia (CDL) and Brown-Teitelboim (BT), as well as the Hamiltonian formalism of Fischler, Morgan and Polchinski (FMP). The resulting similarities and differences in between the three approaches are compared with their respective 4D realisations. For CDL, the total bounce can be expressed as the product of relative entropies, whereas, for the case of BT and FMP, the transition rate can be written as the difference of two generalised entropies. By means of holographic arguments, we show that the Euclidean methods, as well as the Lorentzian cases without non-extremal black holes, provide examples of an AdS2/CFT1 ⊂ AdS3/CFT2 correspondence. Such embedding is not possible in the presence of islands for which the setup corresponds to AdS2/CFT1 ⊄ AdS3/CFT2. We find that whenever an island is present, up-tunnelling is possible.
On the 3D Navier–Stokes equations with a linear multiplicative noise and prescribed energy
Authors: Berkemeier Stefanie Elisabeth 
Published: May 2023

AbstractFor a prescribed deterministic kinetic energy, we use convex integration to construct analytically weak and probabilistically strong solutions to the 3D incompressible Navier–Stokes equations driven by a linear multiplicative stochastic forcing. These solutions are defined up to an arbitrarily large stopping time and have deterministic initial values, which are part of the construction. Moreover, by a suitable choice of different kinetic energies which coincide on an interval close to time 0, we obtain non-uniqueness.
Human-centric AI: philosophical and community-centric considerations
Authors: Taylor Randon R. , O’Dell Bessie , Murphy John W. 
Published: May 2023

AbstractThis article provides a course of correction in the discourse surrounding human-centric AI by elucidating the philosophical underpinning that serves to create a view that AI is divorced from human-centric values. Next, we espouse the need to explicitly designate stakeholder- or community-centric values which are needed to resolve the issue of alignment. To achieve this, we present two frameworks, Ubuntu and maximum feasible participation. Finally, we demonstrate how employing the aforementioned frameworks in AI can benefit society by flattening the current top-down social hierarchies as AI is currently being utilized. Implications are discussed.
Non-intersecting Path Constructions for TASEP with Inhomogeneous Rates and the KPZ Fixed Point
Authors: Bisi Elia , Liao Yuchen , Saenz Axel , Zygouras Nikos 
Published: May 2023

AbstractWe consider a discrete-time TASEP, where each particle jumps according to Bernoulli random variables with particle-dependent and time-inhomogeneous parameters. We use the combinatorics of the Robinson–Schensted–Knuth correspondence and certain intertwining relations to express the transition kernel of this interacting particle system in terms of ensembles of weighted, non-intersecting lattice paths and, consequently, as a marginal of a determinantal point process. We next express the joint distribution of the particle positions as a Fredholm determinant, whose correlation kernel is given in terms of a boundary-value problem for a discrete heat equation. The solution to such a problem finally leads us to a representation of the correlation kernel in terms of random walk hitting probabilities, generalizing the formulation of Matetski et al. (Acta Math. 227(1):115–203, 2021) to the case of both particle- and time-inhomogeneous rates. The solution to the boundary value problem in the fully inhomogeneous case appears with a finer structure than in the homogeneous case.
Long-Term Pollution Does Not Inhibit Denitrification and DNRA by Adapted Benthic Microbial Communities
Authors: Broman Elias , Abdelgadir Mohanad , Bonaglia Stefano , Forsberg Sara C. , Wikström Johan , Gunnarsson Jonas S. , Nascimento Francisco J. A. , Sjöling Sara 
Published: May 2023

Abstract Denitrification in sediments is a key microbial process that removes excess fixed nitrogen, while dissimilatory nitrate reduction to ammonium (DNRA) converts nitrate to ammonium. Although microorganisms are responsible for essential nitrogen (N) cycling, it is not yet fully understood how these microbially mediated processes respond to toxic hydrophobic organic compounds (HOCs) and metals. In this study, we sampled long-term polluted sediment from the outer harbor of Oskarshamn (Baltic Sea), measured denitrification and DNRA rates, and analyzed taxonomic structure and N-cycling genes of microbial communities using metagenomics. Results showed that denitrification and DNRA rates were within the range of a national reference site and other unpolluted sites in the Baltic Sea, indicating that long-term pollution did not significantly affect these processes. Furthermore, our results indicate an adaptation to metal pollution by the N-cycling microbial community. These findings suggest that denitrification and DNRA rates are affected more by eutrophication and organic enrichment than by historic pollution of metals and organic contaminants.