bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Identification of Enteric Fever-Specific Antigens for Population-Based Serosurveillance
Authors: Mylona Elli , Hefele Lisa , Tran Vu Thieu Nga , Trinh Van Tan , Nguyen Ngoc Minh Chau , Tran Tuan Anh , Karkey Abhilasha , Dongol Sabina , Basnyat Buddha , Voong Vinh Phat , Ho Ngoc Dan Thanh , Russell Paula , Charles Richelle C , Parry Christopher M , Baker Stephen 
Published: July 2023

Abstract

Background
Enteric fever, caused by Salmonella enterica serovars Typhi and Paratyphi A, is a major public health problem in low- and middle-income countries. Moderate sensitivity and scalability of current methods likely underestimate enteric fever burden. Determining the serological responses to organism-specific antigens may improve incidence measures.

Methods
Plasma samples were collected from blood culture-confirmed enteric fever patients, blood culture-negative febrile patients over the course of 3 months, and afebrile community controls. A panel of 17 Salmonella Typhi and Paratyphi A antigens was purified and used to determine antigen-specific antibody responses by indirect ELISAs.

Results
The antigen-specific longitudinal antibody responses were comparable between enteric fever patients, patients with blood culture-negative febrile controls, and afebrile community controls for most antigens. However, we found that IgG responses against STY1479 (YncE), STY1886 (CdtB), STY1498 (HlyE), and the serovar-specific O2 and O9 antigens were greatly elevated over a 3-month follow up period in S. Typhi/S. Paratyphi A patients compared to controls, suggesting seroconversion.

Conclusions
We identified a set of antigens as good candidates to demonstrate enteric fever exposure. These targets can be used in combination to develop more sensitive and scalable approaches to enteric fever surveillance and generate invaluable epidemiological data for informing vaccine policies.

Clinical Trial Registration
ISRCTN63006567.
Prior Herpes Simplex Virus Infection and the Risk of Herpes Zoster
Authors: Harbecke Ruth , Oxman Michael N , Selke Stacy , Ashbaugh Mark E , Lan Kristine F , Koelle David M , Wald Anna 
Published: July 2023

Abstract

Background
The incidence of herpes zoster (HZ) has increased in the United States concurrent with decrease in herpes simplex virus (HSV) prevalence. We hypothesized that lack of HSV-elicited cross-reactive immunity to varicella-zoster virus (VZV) results in an increased risk of HZ. Using specimens from the placebo arm of the Shingles Prevention Study, we investigated whether persons who develop HZ are less likely to have prior HSV infection than persons who do not develop HZ, and whether HZ is less severe in persons with HSV than in HSV seronegative persons.

Methods
We conducted a nested case-control (1:2) study comparing the seroprevalence of HSV-1 and HSV-2 in cases (persons with polymerase chain reaction-confirmed HZ) to age-, sex-, and health-matched controls (persons without HZ).

Results
Sera from 639 study participants (213 cases and 426 controls) yielded definitive HSV antibody results and were analyzed. Overall, HSV seropositivity rate was 75%. HSV seronegativity was significantly higher in HZ cases than controls (30.5% vs 22.3%; P = .024), with a 55% higher risk of HZ in HSV seronegative than HSV seropositive participants. HSV seropositivity was associated with more severe HZ (P = .021).

Conclusions
Our study demonstrated that prior infection with HSV partly protects against HZ.
Political Visual Literacy
Authors: Galai Yoav 
Published: July 2023

Abstract
Visual politics is a fast-growing field and much of it is focused on images that inspire criticism. This tendency results in a lack of attention to oppressive visual practices. A political visual literacy approaches all visual practices as being layered with different “visual truths” that were developed in response to political commitments over time. These “visual truths” inflected visual practices in ways that may outlive the political settings in which they were first articulated. Most important of these is the desire to capture human difference that framed the development of visual technologies and is still embedded in a range of visual practices. The methodology I develop here links a conjunctural analysis of visual tools and practices and the visual truths implicated in them with their operationalisation by actors as cultural tools through the framework of mediated action. I develop this approach by interrogating two layered and harmful visual practices: the White-centrism of visual technologies and the racialised origins of transphobic visualities in automatic gender recognition technology.
Antimicrobial efficiency of chlorine dioxide and its potential use as anti-SARS-CoV-2 agent: mechanisms of action and interactions with gut microbiota
Authors: Peredo-Lovillo Audry , Romero-Luna Haydee Eliza , Juárez-Trujillo Naida , Jiménez-Fernández Maribel 
Published: July 2023

Abstract
Chlorine dioxide (ClO2) is a disinfectant gas with strong antifungal, antibacterial, and antiviral activities. Applied on hard, non-porous surfaces as an aqueous solution or gas, the ClO2 exerts antimicrobial activity through its interaction and destabilization of cell membrane proteins, as well as through DNA/RNA oxidation, triggering cell death. As for viruses, the ClO2 promotes protein denaturalization mechanisms, preventing the union between the human cells and the viral envelope. Currently, ClO2 has been pointed out as a potential anti-SARS-CoV-2 clinical treatment for use in humans with the ability to oxidize the cysteine residues in the spike protein of SARS-CoV-2, inhibiting the subsequent binding with the Angiotensin-converting enzyme type 2 receptor, located in the alveolar cells. Orally administered ClO2 reaches the gut tract and exacerbates the symptoms of COVID-19, generating a dysbiosis with gut inflammation and diarrhea as side effects, and once absorbed, produces toxic effects including methemoglobinemia and hemoglobinuria, which can trigger respiratory diseases. These effects are dose-dependent and may not be entirely consistent between individuals since the gut microbiota composition is highly heterogeneous. However, to support the use of ClO2 as an anti-SARS-CoV-2 agent, further studies focused on its effectiveness and safety both in healthy and immunocompromised individuals, are needed.
Final Price Neglect in Multi-Product Promotions: How Non-Integrated Price Reductions Promote Higher-Priced Products
Authors: Jia He (Michael) , Huang Yunhui , Zhang Qiang , Shi Zhengyu , Zhang Ke 
Published: July 2023

Abstract
Price reductions take either an integrated form (e.g., a discount shown directly on the price tag) or a non-integrated form (e.g., a discount contained in a coupon sent to consumers and thus separate from the price tag). This research examines how non-integrated versus integrated promotions influence choices among vertically differentiated products. Under an integrated promotion (e.g., $10 off) applicable to multiple products (e.g., original list prices: $50 vs. $30), consumers directly compare these products’ post-promotion final prices displayed on their price tags (after a reduction of $10: $40 vs. $20). In contrast, under a non-integrated promotion of the same monetary value, consumers simply compare these products’ original list prices ($50 vs. $30) and neglect their post-promotion final prices, which require calculations. The list prices ($50 vs. $30; relative to the final prices: $40 vs. $20) as a basis for price comparison reduce the perceived price difference between these products. Consequently, a non-integrated promotion (compared to an integrated promotion) increases consumers’ choice of higher-priced products. A series of experiments (N = 5,187) demonstrate this effect and support the final price neglect mechanism. Furthermore, although attenuated, this effect still emerges for price reductions of a smaller magnitude or in a percent-off format.
The role of personal and impersonal relational contracts on partner selection and efficiency
Authors: Muñoz-Herrera Manuel , Reuben Ernesto 
Published: July 2023

Abstract
In this article, we use a laboratory experiment to study the effects of relational contracts on market efficiency in environments with different degrees of contract enforceability and market competition. By exogenously varying the communication protocol, we create relational contracts that are more personal or impersonal. On the one hand, personal relational contracts improve efficiency by promoting trust and coordination. On the other hand, impersonal relational contracts increase efficiency by facilitating the severance of trading relationships when more productive competitors enter the market. Therefore, the overall effect on market efficiency depends on the relative importance of competition and agreement enforceability (JEL D91, L22, L14).
Care ethics, needs-recognition, and teaching encounters
Authors: Seton Bennett Pip 
Published: July 2023

AbstractCare ethics takes as central the discerning of needs in those being cared for and attempts to meet those needs. Perceptive caring agents are more likely to be able to identify needs in those for whom they are caring. The identification of needs is no small matter, not least in teaching encounters. This paper modestly proposes that at least some of the needs a caring agent should attempt to meet are a function of the identity of the patient of caring action. Taking Nel Noddings’ account of care ethics as representative, I present it in outline. This leads to the needs-identification problematic. Following this I turn to Soran Reader’s account of needs. I interpret this to offer what I designate as identity as ‘what-ness’. Such an understanding of identity-based needs is a starting point for the caring agent but a more nuanced account, of identity as ‘who-ness’, is argued to be preferable. Identity as ‘who-ness’, as expressed in Paul Ricoeur’s work, advances the discussion, culminating in his concept of the ‘capable human being’. Having brought this aspect of Ricoeur’s thought into conversation with care ethics, I offer an account of identity-based needs conducive to the broader aims of the care ethical project. Finally, I consider what this bolstered account of care ethics might say about a brief and illustrative teaching encounter.
Cluster extent inference revisited: quantification and localisation of brain activity
Authors: Goeman Jelle J , Górecki Paweł , Monajemi Ramin , Chen Xu , Nichols Thomas E , Weeda Wouter 
Published: July 2023

Abstract
Cluster inference based on spatial extent thresholding is a popular analysis method multiple testing in spatial data, and is frequently used for finding activated brain areas in neuroimaging. However, the method has several well-known issues. While powerful for finding regions with some activation, the method as currently defined does not allow any further quantification or localisation of signal. In this paper, we repair this gap. We show that cluster-extent inference can be used (1) to infer the presence of signal in any region of interest and (2) to quantify the percentage of activation in such regions. These additional inferences come for free, i.e. they do not require any further adjustment of the alpha-level of tests, while retaining full family-wise error control. We achieve this extension of the possibilities of cluster inference by embedding the method into a closed testing procedure, and solving the graph-theoretic k-separator problem that results from this embedding. We demonstrate the usefulness of the improved method in a large-scale application to neuroimaging data from the Neurovault database.
Endometrioma causing recurrent small bowel obstruction in a virgin abdomen—a case report and literature review
Authors: Chiu Tricia , Niranjan Nithya , FitzGerald Kate 
Published: July 2023

Abstract
There has been a modest number of cases of bowel obstruction secondary to endometriosis reported. Delays in diagnoses can cause significant morbidity to patients. We describe the case of a 45-year-old female with a 2-year history of recurrent small bowel obstructions (SBOs) without a history of abdominal surgery. She underwent multiple computed tomography scans, and a magnetic resonance enterography, which queried possible terminal ileitis secondary to Crohn’s fibro-stenosing disease or a Meckel’s diverticulum. Colonoscopy up to TI was normal. Elective laparoscopy showed a cicatrizing small bowel mass in her distal ileum ~15 cm from the TI, which was resected. There were no other findings. Histopathological testing revealed endometriosis. At 2-month post-resection, she remains symptom-free and was referred to gynaecology. Endometriosis causing bowel obstruction should be considered early in female patients, especially those with virgin abdomens. Timely elective laparoscopy is a safe and effective way of diagnosing and treating small bowel obstruction, avoiding an emergency procedure.
The Silence of the Bride: A Fatimid marriage contract on silk
Authors: Alrudainy Reem , Tillier Mathieu , Vanthieghem Naïm 
Published: July 2023

Abstract
Marriage contracts and divorce deeds are of particular importance for historians, as they provide clues about both social practices and gender relations. In this article, we offer an edition of a noteworthy document from Dār al-āthār al-islāmiyya in Kuwait, which, beyond its remarkable aesthetic quality, offers a testimony to marriage and divorce practices in a bourgeois milieu of the Egyptian capital during the late Fatimid period. More than a micro-history, this document adds a new piece to the picture of matrimonial dynamics in medieval Egypt, which were often more subtle than previously understood. Patriarchal authority did not prevent a father from deploying all sorts of strategies to protect his daughter in marriage and guarantee her a certain amount of autonomy. In accordance with some jurists’ recommendations, which were based on a Prophetic hadith, the father did not marry off his daughter without first obtaining her tacit permission. Finally, the document preserves the memory of a marital crisis in the seventh year of marriage, during which the husband repudiated his wife before rapidly taking her back.
Spectroscopic Observation and Modeling of Photonic Modes in CeO2 Nanostructures
Authors: Wang Yifan , Yang Shize , Crozier Peter A 
Published: July 2023

Abstract
Photonic modes in dielectric nanostructures, e.g., wide gap semiconductor like CeO2 (ceria), have the potential for various applications such as information transmission and sensing technology. To fully understand the properties of such phenomenon at the nanoscale, electron energy-loss spectroscopy (EELS) in a scanning transmission electron microscope was employed to detect and explore photonic modes in well-defined ceria nanocubes. To facilitate the interpretation of the observations, EELS simulations were performed with finite-element methods. The simulations allow the electric and magnetic field distributions associated with different modes to be determined. A simple analytical eigenfunction model was also used to estimate the energy of the photonic modes. In addition, by comparing various spectra taken at different location relative to the cube, the effect of the surrounding environment on the modes could be sensed. This work gives a high-resolution description of the photonic modes' properties in nanostructures, while demonstrating the advantage of EELS in characterizing optical phenomena locally.
Exoplanet spectroscopy with JWST NIRISS: diagnostics and case studies
Authors: Holmberg Måns , Madhusudhan Nikku 
Published: July 2023

ABSTRACT
The JWST is ushering in a new era in remote sensing of exoplanetary atmospheres. Atmospheric retrievals of exoplanets can be highly sensitive to high-precision JWST data. It is, therefore, imperative to characterize the instruments and noise sources using early observations to enable robust characterization of exoplanetary atmospheres using JWST-quality spectra. This work is a step in that direction, focusing on the Near Infrared Imager and Slitless Spectrograph (NIRISS) Single Object Slitless Spectroscopy (SOSS) instrument mode, with a wavelength coverage of 0.6–2.8 $\mu$m and R ∼ 700. Using a custom-built pipeline, JExoRES, we investigate key diagnostics of NIRISS SOSS with observations of two giant exoplanets, WASP-39 b and WASP-96 b, as case studies. We conduct a detailed evaluation of the different aspects of the data reduction and analysis, including sources of contamination, 1/f noise, and system properties such as limb darkening. The slitless nature of NIRISS SOSS makes it susceptible to contamination due to background sources. We present a method to model and correct for dispersed field stars that can significantly improve the accuracy of the observed spectra. In doing so, we also report an empirically determined throughput function for the instrument. We find significant correlated noise in the derived spectra, which may be attributed to 1/f noise, and discuss its implications for spectral binning. We quantify the covariance matrix that would enable the consideration of correlated noise in atmospheric retrievals. Finally, we conduct a comparative assessment of NIRISS SOSS spectra of WASP-39 b reported using different pipelines and highlight important lessons for exoplanet spectroscopy with JWST NIRISS.
Trajectory-based RFI subtraction and calibration for radio interferometry
Authors: Finlay Chris , Bassett Bruce A , Kunz Martin , Oozeer Nadeem 
Published: July 2023

ABSTRACT
Radio interferometry calibration and radio frequency interference (RFI) removal are usually done separately. Here we show that jointly modelling the antenna gains and RFI has significant benefits when the RFI follows precise trajectories, such as for satellites. One surprising benefit is improved calibration solutions, by leveraging the RFI signal itself. We present trajectory-based RFI subtraction and calibration (tabascal), a new algorithm that jointly models the RFI and calibration parameters in visibilities. We test tabascal on simulated MeerKAT calibration observations contaminated by satellite-based RFI. We obtain gain estimates that are both unbiased and up to an order of magnitude better constrained compared to uncontaminated data. When combined with an ad hoc RFI subtraction scheme, tabascal solutions can be further applied to an adjacent target observation: 5 min of calibration data results in an image with about a third the noise achieved when using flagging alone. The recovered flux distribution of RFI subtracted data was on par with uncontaminated data. In contrast, RFI flagging alone resulted in a higher detection threshold and consistent underestimation of source fluxes. For a mean RFI amplitude of 17 Jy, using RFI subtraction leads to less than 1 per cent loss of data compared to 75 per cent data loss from an ideal 3σ flagging algorithm, a very significant increase in data available for science analysis. Although we have examined the case of satellite RFI, tabascal should work for any RFI moving on parametrizable trajectories, relative to the phase centre, such as planes and/or objects fixed to the ground.
Probing bursty star formation by cross-correlating extragalactic background light and galaxy surveys
Authors: Sun Guochao , Lidz Adam , Faisst Andreas L , Faucher-Giguère Claude-André 
Published: July 2023

ABSTRACT
Understanding the star formation rate (SFR) variability and how it depends on physical properties of galaxies is important for developing and testing the theory of galaxy formation. We investigate how statistical measurements of the extragalactic background light (EBL) can shed light on this topic and complement traditional methods based on observations of individual galaxies. Using semi-empirical models of galaxy evolution and SFR indicators sensitive to different star formation time-scales (e.g. H α and ultraviolet continuum luminosities), we show that the SFR variability, quantified by the joint probability distribution of the SFR indicators (i.e. the bivariate conditional luminosity function), can be characterized as a function of galaxy mass and redshift through the cross-correlation between deep, near-infrared maps of the EBL and galaxy distributions. As an example, we consider combining upcoming SPHEREx maps of the EBL with galaxy samples from Rubin Observatory Legacy Survey of Space and Time. We demonstrate that their cross-correlation over a sky fraction of fsky ∼ 0.5 can constrain the joint SFR indicator distribution at high significance up to z ∼ 2.5 for mass-complete samples of galaxies down to $M_{*}\sim 10^9\, {\rm M}_{\odot }$. These constraints not only allow models of different SFR variability to be distinguished, but also provide unique opportunities to investigate physical mechanisms that require large number statistics such as environmental effects. The cross-correlations investigated illustrate the power of combining cosmological surveys to extract information inaccessible from each data set alone, while the large galaxy populations probed capture ensemble-averaged properties beyond the reach of targeted observations towards individual galaxies.
Halo assembly bias from a deep learning model of halo formation
Authors: Lucie-Smith Luisa , Barreira Alexandre , Schmidt Fabian 
Published: July 2023

ABSTRACT
We build a deep learning framework that connects the local formation process of dark matter haloes to the halo bias. We train a convolutional neural network (CNN) to predict the final mass and concentration of dark matter haloes from the initial conditions. The CNN is then used as a surrogate model to derive the response of the haloes’ mass and concentration to long-wavelength perturbations in the initial conditions, and consequently the halo bias parameters following the ‘response bias’ definition. The CNN correctly predicts how the local properties of dark matter haloes respond to changes in the large-scale environment, despite no explicit knowledge of halo bias being provided during training. We show that the CNN recovers the known trends for the linear and second-order density bias parameters b1 and b2, as well as for the local primordial non-Gaussianity linear bias parameter bϕ. The expected secondary assembly bias dependence on halo concentration is also recovered by the CNN: at fixed mass, halo concentration has only a mild impact on b1, but a strong impact on bϕ. Our framework opens a new window for discovering which physical aspects of the halo’s Lagrangian patch determine assembly bias, which in turn can inform physical models of halo formation and bias.