bluuebunny/crossref_metadata_2025_split huggingface dataset:
Role of authentic leadership in enhancing employees' voice behavior through psychological capital during COVID-19 pandemic
Authors: Rafique Noman , Afshan Gul , Ahmed Farooque 
Published: June 2023

PurposeConsidering the importance of employees' voice behavior (VB) and psychological capital (PC) amidst the coronavirus disease 2019 (COVID-19), this study highlights the role of authentic leadership (AL) in building a psychologically strong workforce that can provide meaningful suggestions for the improvement of organization.Design/methodology/approachThe study employed a questionnaire survey to collect the data and recruited 261 participants from the telecom sector Sindh, Pakistan. The data analysis was done using partial least squares structural equation modeling (PLS-SEM).FindingsThe findings of the study supported the hypotheses suggesting that AL can directly influence employees' VB and indirectly via PC.Originality/valueThe study was conducted during the COVID-19 in the telecom sector of Sindh, Pakistan. This study contributes by providing useful insights into that AL is an important form of leadership that encourages employees' voluntary behavior and psychological strength during the COVID-19 pandemic.
The dark side of mobile apps: when and how technical security matters for in-app purchases?
Authors: Liu Yulong (David) , Chung Henry F. L. , Zhang Zuopeng (Justin) , Wu Mian 
Published: June 2023

PurposeThis research aims to explore the dark side of mobile applications by investigating the role of apps' technicality and app security in the mechanism of user satisfaction, app intention and customers' continuance tendency to make in-app purchases.Design/methodology/approachDrawing on attitude-behavior-context (ABC) theory, the study proposed a conceptual framework and examined the framework using a structural equation modeling (SEM) approach based on data collected from app users from New Zealand.FindingsThe results reveal the correlation between user satisfaction and in-app purchase with a mediator of app continuance intention (ACI). In particular, the results show that app technicality (AT) has a positive correlation with user satisfaction as an antecedent. App security and hedonic value are positively correlated with user satisfaction.Originality/valueThe research has three critical research implications. First, this research advances the understanding of the dark side of mobile apps by showing how app security influences customers' in-app purchases. Secondly, this study reveals and offers empirical evidence for the mechanism between app security and user satisfaction. Finally, the study provides empirical evidence of AT as a distal antecedent for in-app purchases.
Determinants of job insecurity during COVID-19: quantitative insights from the Romanian labor market
Authors: Rusu Mihai Stelian , Popa Adela Elena , Pogan Livia Dana , Gutoiu Giorgian Ionut 
Published: June 2023

PurposeFollowing the COVID-19 pandemic, the issues related to job insecurity became even more prominent than before. This paper sets out to identify the determinants of job insecurity in the context of the COVID-19 pandemic among Romanian workers, a topic than was scarcely addressed in previous studies.Design/methodology/approachBased on a representative sample at the national level (N = 744), the authors performed a multilinear regression analysis that pinpoints the factors predicting job insecurity.FindingsThis study findings indicate that high-skilled workers employed on permanent arrangements, having higher workloads, who had received organizational support, and managed to harmonize work demands with family responsibilities experience the lowest levels of job insecurity. In this study, teleworking does not influence the level of job insecurity. Gender (being male), working in the public sector and approving the political management of the COVID-19 pandemic also count in securing the feelings employees have about their job.Originality/valueBesides filling a geographical gap in the literature, another innovative contribution of the paper is the emphasis on the importance for the employees of how public authorities manage the public health crisis. Also, this study explores the workload as a factor of job insecurity which was unaddressed previously. Implications for research and practice are emphasized.
The autobiography of environmental, social and governance (ESG)
Authors: Singh Kuldeep 
Published: June 2023

PurposeThe current essay aims to generate critical reflections on environment, social and governance (ESG) based on observations, experiences, literature reviews and logical reasoning.Design/methodology/approachThe essay adopts the methodology of first-person omniscient, where the narrator (ESG in this essay) is a character in the story. In this methodology, the ESG is also aware of the thoughts and feelings of all the other characters, such as the ESG practitioners, academics, researchers, lawmakers and relevant stakeholders.FindingsThe essay concludes that the relevance of ESG is broader than what is currently perceived. The piece endorses a view to look at ESG from other perspectives and benefits, not only from its financial relevance. It should be understood and implemented at the grassroots level.Originality/valueThe essay is one of its kind to reflect on the current ESG landscape. It attempts to redirect the debate on ESG toward the origin of its very existence.
Leader's role in the development of collective competencies of fashion work teams
Authors: da Silva Luiz Henrique , Ghedine Tatiana , da Silva Francielle Molon 
Published: June 2023

PurposeThis article aims to analyze the way the leader acts in the development of collective competencies (CC) of fashion work teams, seeking to demonstrate ways in which the leader can collaborate for the development of the collective work.Design/methodology/approachWith a qualitative approach, this paper carried out a case study strategy having the Creation Center of a fashion group from Santa Catarina, Brazil as a research object. Data collection took place through semi-structured interviews and participant observation with 36 employees from 6 work teams from 5 clothing brands.FindingsOur findings make it clear that the leader influences the CC development of fashion work teams. The leader's role becomes essential for directing and developing his team, seeking to encourage participation and cooperation between team members to achieve the objectives and expected results. It was considered that the CC development could be associated with how much the leader represents his team and contributes with guidelines that emphasize the collective and the people and teams' development. The leader who makes the cooperative relationship feasible, encourages effort and promotes cohesion and teamwork tends to collaborate with actions that foster CC development.Originality/valueFrom a theoretical perspective, it is the first study to analyze empirically the relationship between leadership and CC. A model with 18 guidelines was developed, divided into six determining factors (activity dynamics, team composition, individual characteristics and dispositions, team integration, communication and physical structure) that demonstrated the way the leader collaborates for the CC development. For the fashion industry, this study demonstrates elements capable of assisting collective creativity and the development of fashion collections.
Cell surface composition, released polysaccharides, and ionic strength mediate fast sedimentation in the cyanobacterium Synechococcus elongatusPCC 7942
Authors: Zedler Julie A. Z. , Michel Marlene , Pohnert Georg , Russo David A. 
Published: June 2023

AbstractCyanobacteria are photosynthetic prokaryotes of high ecological and biotechnological relevance that have been cultivated in laboratories around the world for more than 70 years. Prolonged laboratory culturing has led to multiple microevolutionary events and the appearance of a large number of ‘domesticated’ substrains among model cyanobacteria. Despite its widespread occurrence, strain domestication is still largely ignored. In this work we describe Synechococcus elongatus PCC 7942‐KU, a novel domesticated substrain of the model cyanobacterium S. elongatus PCC 7942, which presents a fast‐sedimenting phenotype. Under higher ionic strengths the sedimentation rate increased leading to complete sedimentation in just 12 h. Through whole genome sequencing and gene deletion, we demonstrated that the Group 3 alternative sigma factor F plays a key role in cell sedimentation. Further analysis showed that significant changes in cell surface structures and a three‐fold increase in released polysaccharides lead to the appearance of a fast‐sedimenting phenotype. This work sheds light on the determinants of the planktonic to benthic transitions and provides genetic targets to generate fast‐sedimenting strains that could unlock cost‐effective cyanobacterial harvesting at scale.
Citizenship status and cost‐related nonadherence in the United States, 2017–2021
Authors: Guadamuz Jenny S. , Qato Dima M. 
Published: June 2023

AbstractObjectiveTo assess inequities in prescription medication use and subsequent cost‐related nonadherence (CRN) and cost‐saving strategies by citizenship status in the United States.Data Sources/Study SettingNational Health Interview Survey (2017–2021).Study DesignThis cross‐sectional study examined noncitizen (n = 8596), naturalized citizen (n = 12,800), and US‐born citizen (n = 120,195) adults. We also examined older adults (≥65 years) separately, including noncitizens without Medicare (a group of importance given their immigration‐related barriers to health care access). Multiple mediation analysis was used to examine differences in CRN and determine whether economic, health care, and immigration factors explain observed inequities.Principal FindingsNoncitizens (41.9%) were less likely to use prescription medications than naturalized (60.5%) and US‐born citizens (68.2%). Among prescription medication users, noncitizens (13.8%) were more likely to report CRN than naturalized (9.5%) and US‐born citizens (11.0%). CRN differences between noncitizens and naturalized citizens (OR 1.38, 95% CI 1.21–1.44) and between noncitizens and US‐born citizens (OR 1.23, 95% CI 1.07–1.35) were explained by insurance status and food insecurity. Only 4.9% of medication users turned to alternative therapies to lower their drug costs, but there were no substantial differences across citizenship status. More medication users requested lower‐cost prescriptions (19.0%); however, noncitizens were less likely to make these requests. Older noncitizens without Medicare, of whom 23.9% requested lower‐cost drugs, were an exception. Noncitizens (5.8%), particularly older noncitizens without Medicare (21.8%), were more likely to import their drugs than naturalized (3.5%) and US‐born citizens (1.2%).ConclusionsNoncitizens experience a high burden of cost‐related barriers to prescription medications. Efforts to reduce these inequities should focus on dismantling health care and food access barriers, regardless of citizenship status.
Genetic variation and domestication of horses revealed by 10 chromosome‐level genomes and whole‐genome resequencing
Authors: Gu Jingjing , Li Sheng , Zhu Bo , Liang Qiqi , Chen Bin , Tang Xiangwei , Chen Chujie , Wu Dong‐Dong , Li Yan 
Published: June 2023

AbstractUnderstanding the genetic variations of the horse (Equus caballus) genome will improve breeding conservation and welfare. However, genetic variations in long segments, such as structural variants (SVs), remain understudied. We de novo assembled 10 chromosome‐level three‐dimensional horse genomes, each representing a distinct breed, and analysed horse SVs using a multi‐assembly approach. Our findings suggest that SVs with the accumulation of mammalian‐wide interspersed repeats related to long interspersed nuclear elements might be a horse‐specific mechanism to modulate genome‐wide gene regulatory networks. We found that olfactory receptors were commonly loss and accumulated deleterious mutations, but no purge of deleterious mutations occurred during horse domestication. We examined the potential effects of SVs on the spatial structure of chromatin via topologically associating domains (TADs). Breed‐specific TADs were significantly enriched by breed‐specific SVs. We identified 4199 unique breakpoint‐resolved novel insertions across all chromosomes that account for 2.84 Mb sequences missing from the reference genome. Several novel insertions might have potential functional consequences, as 519 appeared to reside within 449 gene bodies. These genes are primarily involved in pathogen recognition, innate immune responses and drug metabolism. Moreover, 37 diverse horses were resequenced. Combining this with public data, we analysed 97 horses through a comparative population genomics approach to identify the genetic basis underlying breed characteristics using Thoroughbreds as a case study. We provide new scientific evidence for horse domestication, an understanding of the genetic mechanism underlying the phenotypic evolution of horses, and a comprehensive genetic variation resource for further genetic studies of horses.
Mifepristone as a pharmacological intervention for stress‐induced alcohol craving: A human laboratory study
Authors: Haass‐Koffler Carolina L. , Magill Molly , Cannella Nazzareno , Brown Joshua C. , Aoun Elie G. , Cioe Patricia A. , Sinha Rajita , Swift Robert M. , Ciccocioppo Roberto , Leggio Lorenzo 
Published: June 2023

AbstractPreclinical and clinical work suggests that mifepristone may be a viable treatment for alcohol use disorder (AUD). This was a Phase 1/2, outpatient, cross‐over, randomized, double‐blind, placebo‐controlled trial with non‐treatment‐seeking individuals with AUD (N = 32). We assessed safety, alcohol craving and consumption, after 1‐week mifepristone 600 mg/day administration, in a human laboratory study comprised of a single oral yohimbine administration (32.4 mg), a cue‐reactivity procedure and alcohol self‐administration. Safety was monitored by adverse events and hemodynamic parameters, alcohol craving by alcohol craving questionnaire and cue‐induced saliva output. During the alcohol self‐administration, we assessed alcohol pharmacokinetics, subjective effects and consumption. Outcomes were assessed using Generalized Estimating Equations and mediation analysis. Mild‐moderate adverse events were reported in both conditions. There was no statistically significant difference between mifepristone and placebo in alcohol pharmacokinetics and subjective effects. Furthermore, blood pressure increased only in the placebo condition after the stress‐induced laboratory procedures. Mifepristone, compared to placebo, significantly reduced alcohol craving and increased cortisol levels. Mifepristone‐induced cortisol increase was not a mediator of alcohol craving. Mifepristone, compared to placebo, did not reduce alcohol consumption in the laboratory or in a naturalistic setting. This study successfully translated a developed preclinical procedure to a human laboratory study, confirming the safety of mifepristone in people with AUD and providing evidence to its role in reducing alcohol craving under stress procedures. The lack of effects on alcohol drinking may be related to the selection of non‐treatment seekers and suggests future treatment‐oriented trials should investigate mifepristone in people with AUD.
Aging out of WIC and child nutrition: Evidence from a regression discontinuity design
Authors: Smith Travis A. , Valizadeh Pourya 
Published: June 2023

AbstractThe Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) is the third largest food assistance program in the United States. Child participants lose WIC in the month following their fifth birthday. We use this exogenous program rule for identification and find diet quality declines nearly 20%, on average, for those who have yet to transition into kindergarten. Decreases are mainly driven by reduced consumption of healthier WIC‐targeted foods. A quantile regression discontinuity approach reveals children prone to lower quality diets experience the largest decreases in diet quality, reaching nearly 30%, whereas those prone to higher quality diets experience no aging‐out‐of‐WIC effects. There are no effects on calorie consumption, regardless of school attendance, indicating caregivers maintain diet quantity for children at the expense of diet quality. Policy implications include allowing children to stay on WIC until they enter kindergarten. We calculate back‐of‐the‐envelope program costs over the next 5 years for such a “kindergarten‐roll‐off” WIC policy under current rules and newly proposed rules to realign WIC packages with the Dietary Guidelines for Americans. Under current rules, costs would average $112 million over the next 5 years (2024–2028), or about 2% of total program costs. Under proposed rule changes, kindergarten‐roll‐off costs would average $144 million per year, or 2.25% of total program costs.
Glutamate dehydrogenase combined with ferrochelatase as a biomarker of liver injury induced by antituberculosis drugs
Authors: He Bei , Cheng Xuan , Xiang Huai‐Rong , Li Yun , Zhang Qi‐Zhi , Peng Wen‐Xing , Yang Bo 
Published: June 2023

AbstractAimsTo explore the potential value of serum glutamate dehydrogenase (GLDH), ferrochelatase (FECH), heme oxygenase‐1 (HO‐1) and glutathione‐S‐transferase‐α (GST‐α) as diagnostic biomarkers for liver injury caused by antituberculosis drugs.MethodsWe established a rat model of isoniazide‐induced liver injury and recruited 122 hospitalized tuberculosis patients taking antituberculosis drugs. We detected the concentration of GLDH, FECH, HO‐1 and GST‐α by enzyme‐linked immunosorbent assay. GraphPad Prism8 and SPSS 26.0 were used for statistical analysis.ResultsIn the rat model, serum GLDH concentration gradually increased during isoniazid (INH) administration, while serum FECH, HO‐1 and GST‐α concentrations significantly increased after INH administration was stopped. The receiver operating characteristic curve showed that the areas under the curve (AUCs) of serum GLDH and FECH for the diagnosis of anti‐tuberculosis (TB) drug‐induced liver injury (anti‐TB‐DILI) were 0.7692 (95% confidence interval [CI] 0.5442‐0.9943) and 0.7284 (95% CI 0.4863‐0.9705) and the diagnostic accuracies were 81.25% and 78.79%, respectively. In clinical research, the AUCs of GLDH and FECH were 0.9124 (95% CI 0.8380‐0.9867) and 0.6634 (95% CI 0.5391‐0.7877), and the optimal thresholds were 10.40 mIU/mL and 1.304 ng/mL, respectively. The diagnostic accuracy, specificity and positive predictive value (PPV) of GLDH were 82.61%, 79.38% and 47.22%. We performed a joint diagnostic test for GLDH and FECH. The diagnostic accuracy (90.43%), specificity (91.75%) and PPV (65.21%) of serial tests were better than for GLDH and FECH alone.ConclusionsGLDH in the diagnosis of liver injury induced by anti‐TB drugs has high sensitivity, but low specificity and low PPV. The combination of GLDH and FECH could significantly improve the specificity, PPV and diagnostic accuracy, and reduce the false‐positive rate of anti‐TB‐DILI.
The severity of SARS‐CoV‐2 infection in K18‐hACE2 mice is attenuated by a novel steroid‐derivative in a gender‐specific manner
Authors: Gupte Sachin A. , Bakshi Chandra Shekhar , Blackham Emma , Duhamel Gerald E. , Jordan Allan , Salgame Padmini , D'silva Melinee , Khan Mohammad Y. , Nadler Jerry , Gupte Rakhee 
Published: June 2023

AbstractBackground and PurposeCOVID‐19 infections caused by SARS‐CoV‐2 disseminated through human‐to‐human transmission can evoke severe inflammation. Treatments to reduce the SARS‐CoV‐2‐associated inflammation are needed and are the focus of much research. In this study, we investigated the effect of N‐ethyl‐N′‐[(3β,5α)‐17‐oxoandrostan‐3‐yl] urea (NEOU), a novel 17α‐ketosteroid derivative, on the severity of COVID‐19 infections.Experimental ApproachStudies were conducted in SARS‐CoV‐2‐infected K18‐hACE2 mice.Key ResultsSARS‐CoV‐2‐infected K18‐hACE2 mice developed severe inflammatory crises and immune responses along with up‐regulation of genes in associated signalling pathways in male more than female mice. Notably, SARS‐CoV‐2 infection down‐regulated genes encoding drug metabolizing cytochrome P450 enzymes in male but not female mice. Treatment with NEOU (1 mg·kg−1·day−1) 24 or 72 h post‐viral infection alleviated lung injury by decreasing expression of genes encoding inflammatory cytokines and chemokines while increasing expression of genes encoding immunoglobins. In situ hybridization using RNA scope™ probes and immunohistochemical assays revealed that NEOU increased resident CD169+ immunoregulatory macrophages and IBA‐1 immunoreactive macrophage‐dendritic cells within alveolar spaces in the lungs of infected mice. Consequentially, NEOU reduced morbidity more prominently in male than female mice. However, NEOU increased median survival time and accelerated recovery from infection by 6 days in both males and females.Conclusions and ImplicationsThese findings demonstrate that SARS‐CoV‐2 exhibits gender bias by differentially regulating genes encoding inflammatory cytokines, immunogenic factors and drug‐metabolizing enzymes, in male versus female mice. Most importantly, we identified a novel 17α‐ketosteroid that reduces the severity of COVID‐19 infection and could be beneficial for reducing impact of COVID‐19.
Changes in alveolar bone width around maxillary implants, as determined through cone beam computed tomography based on bony landmarks: A preliminary study
Authors: Lin Szu‐Wei , Hu Kai‐Fang , Lin Ying‐Chu , Liu Pei‐Feng , Chou Yu‐Hsiang 
Published: June 2023

AbstractPurposeThis study aimed to investigate changes in alveolar bone width around dental implants and identify the anterior nasal spine (ANS), posterior nasal spine (PNS), and floor of the nasal cavity that can be used as reference landmarks for standardizing the orientation of different cone‐beam computed tomography (CBCT) scans.Materials and methodsWe enrolled two groups that comprised 30 implants. Two CBCT scans from the same patient after implant surgery in the first group were obtained to determine differences in the relative distance and angle between the ANS and apex of the dental implant. Then we compared the second group of patients’ presurgical and postsurgical CBCT images to evaluate changes in alveolar bone width after dental implant surgery by the aforementioned bony landmarks.ResultsIn the first group, no statistically significant differences were detected in the mean distance between the ANS, PNS and implant tip in different directions. In the second group, bone width increased at 1 mm (p = 0.020) and decreased at 4 mm (p < 0.001) and 7 mm (p < 0.001) below the alveolar bone crest after implant surgery.ConclusionsWithin the limitations of the present study, the ANS, PNS, and floor of the nasal cavity can be useful in standardizing the orientation of CBCT scans and alveolar bone remodeling after implant surgery varied depending on the height and direction from the alveolar bone crest based on the three landmarks.