bluuebunny/crossref_metadata_2025_split huggingface dataset:
Precarious Manhood Beliefs Are Positively Associated with Erectile Dysfunction in Cisgender Men
Authors: Walther Andreas , Rice Timothy , Eggenberger Lukas 
Published: June 2023

AbstractThe notions that manhood is hard to attain, easy to lose, and needs to be proven via public action constitute precarious manhood beliefs (PMB). PMB is a new concept and it remains unclear whether and how PMB relate to erectile dysfunction (ED) in cisgender men. The ability to achieve an erection remains considered as a cornerstone of masculinity and sexual performance can be conceived as a proof of one’s masculinity. In this context, ED can be received as sexual failure and a threat to a man’s masculinity and sense of adequacy. For these reasons, the hypothesis that PMB are associated with ED warranted empirical testing. In an anonymous online survey focusing on men’s mental health conducted in German-speaking countries of Europe, 507 cisgender men (Mage = 44.2, SDage = 15.2) completed measures on PMB, sexual function, self-stigma, social desirability, and conformity to traditional masculinity ideology (TMI). Multilinear regression analysis with stepwise introduction of relevant covariates evaluated potential associations between PMB and ED. Of a 507 cisgendered male sample, 63.1% reported an increased risk for ED based on previously established cutoff points. Elevated levels of PMB endorsement among the men predicted reduced sexual and erectile function in all models, even when accounting for relevant control variables such as age, education, self-stigma, social desirability, or conformity to TMI. Group comparisons revealed that the men suffering from ED showed higher levels of PMB endorsement but not self-stigma nor TMI relative to men without ED. PMB are significantly associated with ED. While determining causality will require further study, our results may support the hypothesis that higher levels of PMB endorsement may lead to increased tension to perform sexually, resulting in increased psychological pressure and a higher risk to develop ED.
Spatial patterns of nitrogen isotope ratios in forest soils are related to latitude and soil phosphorus concentration
Authors: Spohn Marie , Stendahl Johan 
Published: June 2023

AbstractThe aim of this study was to identify the parameters that affect the nitrogen (N) isotope ratio (δ15N) in soils of temperate and boreal forests. We measured the δ15N in 30 soil profiles of temperate and boreal forests in Sweden and analyzed the relationships between δ15N in the soils and soil chemical properties as well as site characteristics. In addition, we conducted a meta-analyses of δ15N in the organic layer of European forests. We identified two types of δ15N patterns; in type D soils, the δ15N in the mineral soil decreases with depth, whereas in type C soil, the δ15N in the soil profile is almost constant. Type D soils had a significantly higher δ15N in the organic layer and upper mineral soil than type C soils, which is likely due to N isotope fractionation by ectomycorrhizal fungi in the topsoil. Type D soils were found in boreal forests, but not in temperate forests. They had a significantly lower atmospheric N deposition rate than type C soils, by a factor of 2.3, and a significantly higher phosphorus (P) concentration of the organic layer than type C soils, by a factor of 1.5. We also found that the δ15N was negatively correlated with the N:P ratio of the organic layer (R2 = 0.21, p < 0.001). Across Europe, the δ15N of the organic layer was positively correlated with latitude (R2 = 0.58, p < 0.001), and negatively with mean annual temperature (R2 = 0.52, p < 0.001) and atmospheric N deposition (R2 = 0.42, p < 0.001). In conclusion, our results show that the δ15N of the organic layer and microbial N (re-)cycling in forest soils is positively related with latitude and the P concentration of the organic layer.
Sex Differences in Neural Correlates of Emotion Regulation in Relation to Resting Heart Rate Variability
Authors: Min Jungwon , Koenig Julian , Nashiro Kaoru , Yoo Hyun Joo , Cho Christine , Thayer Julian F. , Mather Mara 
Published: June 2023

AbstractPrior studies suggest that sex differences in emotion regulation (ER) ability contribute to sex disparities in affective disorders. In behavioral studies, females rely more on maladaptive strategies to cope with emotional distress than males. Neuroimaging studies suggest that males more efficiently regulate emotion than females by showing less prefrontal cortex activity (suggesting less effort) for similar amygdala activity (similar regulation outcome). However, physiological studies involving heart rate variability (HRV) indicated that, compared with males, females have higher resting HRV, indicative of parasympathetic dominance and better control of emotion. To help resolve these apparently inconsistent findings, we examined sex differences in how resting HRV relates to brain activity while using cognitive reappraisal, one of the adaptive strategies. Based on 51 males and 49 females, we found that females showed different levels of self-rated emotional intensity and amygdala activity for negative versus positive emotions, while males did not. Females also showed greater overall prefrontal cortex activity but similar levels of amygdala activity compared to males. Sex differences in how resting HRV related to brain activity during ER were evident only during viewing or regulating positive emotion. The results suggest that sex differences in the neural correlates of ER and resting HRV might lie in valence more than arousal modulation.
Comparison of Resting-State EEG Network Analyses With and Without Parallel MRI in Genetic Generalized Epilepsy
Authors: van de Velden Daniel , Stier Christina , Kotikalapudi Raviteja , Heide Ev-Christin , Garnica-Agudelo David , Focke Niels K. 
Published: June 2023

AbstractGenetic generalized epilepsy (GGE) is conceptualized as a brain disorder involving distributed bilateral networks. To study these networks, simultaneous EEG-fMRI measurements can be used. However, inside-MRI EEG suffers from strong MR-related artifacts; it is not established whether EEG-based metrics in EEG-fMRI resting-state measurements are suitable for the analysis of group differences at source-level. We evaluated the impact of the inside-MR measurement condition on statistical group comparisons of EEG on source-level power and functional connectivity in patients with GGE versus healthy controls. We studied the cross-modal spatial relation of statistical group differences in seed-based FC derived from EEG and parallel fMRI. We found a significant increase in power and a frequency-specific change in functional connectivity for the inside MR-scanner compared to the outside MR-scanner condition. For power, we found reduced group difference between GGE and controls both in terms of statistical significance as well as effect size. Group differences for ImCoh remained similar both in terms of statistical significance as well as effect size. We found increased seed-based FC for GGE patients from the thalamus to the precuneus cortex region in fMRI, and in the theta band of simultaneous EEG. Our findings suggest that the analysis of EEG functional connectivity based on ImCoh is suitable for MR-EEG, and that relative group difference in a comparison of patients with GGE against controls are preserved. Spatial correspondence of seed-based FC group differences between the two modalities was found for the thalamus.
The special sauce of the Cancer Prevention and Control Research Network: 20 years of lessons learned in developing the evidence base, building community capacity, and translating research into practice
Authors: Wheeler Stephanie B. , Lee Rebecca J. , Young Alexa L. , Dodd Adam , Ellis Charlotte , Weiner Bryan J. , Ribisl Kurt M. , Adsul Prajakta , Birken Sarah A. , Fernández María E. , Hannon Peggy A. , Hébert James R. , Ko Linda K. , Seaman Aaron , Vu Thuy , Brandt Heather M. , Williams Rebecca S. 
Published: June 2023

Abstract
Purpose
The Cancer Prevention and Control Research Network (CPCRN) is a national network focused on accelerating the translation of cancer prevention and control research evidence into practice through collaborative, multicenter projects in partnership with diverse communities. From 2003 to 2022, the CPCRN included 613 members.

Methods
We: (1) characterize the extent and nature of collaborations through a bibliometric analysis of 20 years of Network publications; and (2) describe key features and functions of the CPCRN as related to organizational structure, productivity, impact, and focus on health equity, partnership development, and capacity building through analysis of 22 in-depth interviews and review of Network documentation.

Results
Searching Scopus for multicenter publications among the CPCRN members from their time of Network engagement yielded 1,074 collaborative publications involving two or more members. Both the overall number and content breadth of multicenter publications increased over time as the Network matured. Since 2004, members submitted 123 multicenter grant applications, of which 72 were funded (59%), totaling more than $77 million secured. Thematic analysis of interviews revealed that the CPCRN’s success—in terms of publication and grant productivity, as well as the breadth and depth of partnerships, subject matter expertise, and content area foci—is attributable to: (1) its people–the inclusion of members representing diverse content-area interests, multidisciplinary perspectives, and geographic contexts; (2) dedicated centralized structures and processes to enable and evaluate collaboration; and (3) focused attention to strategically adapting to change.

Conclusion
CPCRN’s history highlights organizational, strategic, and practical lessons learned over two decades to optimize Network collaboration for enhanced collective impact in cancer prevention and control. These insights may be useful to others seeking to leverage collaborative networks to address public health problems.
Mechanisms of action of NME metastasis suppressors – a family affair
Authors: Prunier Céline , Chavrier Philippe , Boissan Mathieu 
Published: June 2023

AbstractMetastatic progression is regulated by metastasis promoter and suppressor genes. NME1, the prototypic and first described metastasis suppressor gene, encodes a nucleoside diphosphate kinase (NDPK) involved in nucleotide metabolism; two related family members, NME2 and NME4, are also reported as metastasis suppressors. These proteins physically interact with members of the GTPase dynamin family, which have key functions in membrane fission and fusion reactions necessary for endocytosis and mitochondrial dynamics. Evidence supports a model in which NDPKs provide GTP to dynamins to maintain a high local GTP concentration for optimal dynamin function. NME1 and NME2 are cytosolic enzymes that provide GTP to dynamins at the plasma membrane, which drive endocytosis, suggesting that these NMEs are necessary to attenuate signaling by receptors on the cell surface. Disruption of NDPK activity in NME-deficient tumors may thus drive metastasis by prolonging signaling. NME4 is a mitochondrial enzyme that interacts with the dynamin OPA1 at the mitochondria inner membrane to drive inner membrane fusion and maintain a fused mitochondrial network. This function is consistent with the current view that mitochondrial fusion inhibits the metastatic potential of tumor cells whereas mitochondrial fission promotes metastasis progression. The roles of NME family members in dynamin-mediated endocytosis and mitochondrial dynamics and the intimate link between these processes and metastasis provide a new framework to understand the metastasis suppressor functions of NME proteins.
Transcriptional landscape of mitochondrial electron transport chain inhibition in renal cells
Authors: Carta Giada , van der Stel Wanda , Scuric Emma W. J. , Capinha Liliana , Delp Johannes , Bennekou Susanne Hougaard , Forsby Anna , Walker Paul , Leist Marcel , van de Water Bob , Jennings Paul 
Published: June 2023

Abstract
Analysis of the transcriptomic alterations upon chemical challenge, provides in depth mechanistic information on the compound’s toxic mode of action, by revealing specific pathway activation and other transcriptional modulations. Mapping changes in cellular behaviour to chemical insult, facilitates the characterisation of chemical hazard. In this study, we assessed the transcriptional landscape of mitochondrial impairment through the inhibition of the electron transport chain (ETC) in a human renal proximal tubular cell line (RPTEC/TERT1). We identified the unfolded protein response pathway (UPR), particularly the PERK/ATF4 branch as a common cellular response across ETC I, II and III inhibitions. This finding and the specific genes elaborated may aid the identification of mitochondrial liabilities of chemicals in both legacy data and prospective transcriptomic studies.
Graphical abstract
Adopting Ocean-Themed Picture Books to Promote Ocean Literacy in Primary Education
Authors: Freitas Cátia , Francis Prue , Bellgrove Alecia , Venzo Paul 
Published: June 2023

AbstractChildren’s literature about the ocean is a valuable learning tool for increasing ocean literacy in formal education. This instruction is, nonetheless, reliant on teachers’ capacity to explore, appreciate and understand the different ways in which elements of picture books convey ocean concepts. As researchers who work collaboratively in marine science education and children’s literature, we analysed a targeted sample of picture books about a largely unknown temperate reef system on the southern coastline of Australia, the Great Southern Reef. Our exploration of these picture books' verbal and visual strategies showed how they can be used as model examples of scientifically accurate educational resources to deliver ocean concepts, increase awareness of a local marine environment, and promote positive attitudes towards science. The portrayal of scientists, particularly female scientists in these texts can also expand children’s perceptions and beliefs about who scientists are and how they work, and ultimately impact young people’s career choices. We argue that the analysis modelled in this article can be adapted to different selections of ocean-themed picture books. Therefore, we provide recommendations for educators in other regions of the world choosing picture books to improve ocean education in the context of other local marine environments.
Evaluation of historical and future thermal conditions for almond trees in north-eastern Portugal
Authors: Freitas Teresa R. , Santos João A. , Silva Ana P. , Fonseca André , Fraga Helder 
Published: June 2023

AbstractThe Trás-os-Montes agrarian region (TM; north-eastern Portugal) is a traditionally growing area of almond trees. However, climate change may significantly alter the current growing conditions and threaten sustainability. Chilling and forcing conditions in TM are assessed herein, also considering different varietal phenological timings. The dynamic model/chill portions (CP) and chilling hour (CH) models are used to assess the chilling phase. For the forcing phase, growing degree hours (GDH) and growing degree days (GDD) models are selected, hinting at differences between simpler (CH and GDD) and more complex models (CP and GDH). Furthermore, the climate change projections for these models are assessed. The models are computed using daily temperatures for baseline (Iberia01, 1971–2015) and two future periods (EURO-CORDEX: medium-term, 2041–2060, and long-term, 2061–2080), following two anthropogenic forcing scenarios (RCP4.5 and RCP8.5). For the future, a five-member ensemble of regional-global climate model chains is used. Projections for CP and CH show decreases, mostly for RCP8.5, whereas projections for GDH and GDD reveal an increase in heat conditions until the beginning of summer. GDH shows that potentially damaging high temperatures during summer, effectively lead to a decrease in heat accumulation for almond trees. CP and GDH, more biologically effective, seem to be more accurate in capturing climate change impacts. For the three varietal groups, the late cultivar may experience a greater reduction of CP and GDH compared to early and mid-season varieties. Nonetheless, the increase in heat forcing should be more detrimental than the decrease in chilling conditions. Although almond production may be compromised in the future, adequate adaptation options are suggested to mitigate future losses of yield/quality and warrant its sustainability.
Computational approaches to detect experts in distributed online communities: a case study on Reddit
Authors: Strukova Sofia , Ruipérez-Valiente José A. , Gómez Mármol Félix 
Published: June 2023

AbstractThe irreplaceable key to the triumph of Question & Answer (Q & A) platforms is their users providing high-quality answers to the challenging questions posted across various topics of interest. From more than a decade, the expert finding problem attracted much attention in information retrieval research. Based on the encountered gaps in the expert identification across several Q & A portals, we inspect the feasibility of identifying data science experts in Reddit. Our method is based on the manual coding results where two data science experts labelled not only expert and non-expert comments, but also out-of-scope comments, which is a novel contribution to the literature, enabling the identification of more groups of comments across web portals. We present a semi-supervised approach which combines 1113 labelled comments with 100,226 unlabelled comments during training. We proved that it is possible to develop models that can identify expert, non-expert and out-of-scope comments peaking the AUC score at 0.93, accuracy at 0.83, MAE at 0.15 degrees and R2 score at 0.69. The proposed model uses the activity behaviour of every user, including Natural Language Processing (NLP), crowdsourced and user feature sets. We conclude that the NLP and user feature sets contribute the most to the better identification of these three classes. It means that this method can generalise well within the domain. Finally, we make a novel contribution by presenting different types of users in Reddit, which opens many future research directions.
Public response to decarbonisation through alternative shipping fuels
Authors: Carlisle Daniel P. , Feetham Pamela M. , Wright Malcolm J. , Teagle Damon A. H. 
Published: June 2023

AbstractAlthough shipping is the most energy efficient method of transporting trade goods it is held accountable for 2–3% of global greenhouse gas (GHG) emissions. The shipping industry is exploring pathways to carbon–neutral fuels to help eliminate GHG emissions by 2050. To date research on alternative fuels has not considered public opinion; it remains unclear whether the public will support alternative shipping fuels, or whether public opposition might prevent or defer their deployment. To fill this knowledge gap and help the industry and policy makers arrive at publicly acceptable decisions, our research examines UK public perceptions of six shipping fuels using a mixed-method approach. Our findings reveal that biofuels and hydrogen are clearly favoured, owing to biofuel’s perceived low risk and hydrogen’s lack of negative by-products. Perceptions of liquid natural gas are somewhat positive, suggesting that it provides an acceptable near-term option while other fuels are developed. Despite lingering stigma, nuclear is preferred over the incumbent heavy fuel oil, though both are perceived negatively. However, the UK public strongly dislike ammonia, perceiving it as unproven, risky, and lacking availability. A third support use of alternative shipping fuels, with support greater from those living near ports—a “yes in my back yard” effect. The results demonstrate that different alternative fuels are likely to elicit different public reactions as they become more widely known and show how the overall evaluations arise from specific positive or negative associations with each fuel.
The IAU recommended photometric system for ultraviolet astronomy
Authors: Gómez de Castro Ana I. , Brosch Noah , Bettoni Daniela , Beitia-Antero Leire , Scowen Paul , Valls-Gabaud David , Sachkov Mikhail 
Published: June 2023

AbstractIn the current era when access to space is becoming easier and at a lower cost thanks to the standardised cubesat technology, numerous missions are expected to be launched to observe, particularly, at ultraviolet wavelengths. Given the reduced dimensions of the telescope that a cubesat can carry, most of these missions will be focused on photometric surveys of a reduced sample of targets of interest, and therefore each mission will define their own photometric bands according to their scientific objectives and orbital constraints. However, in order to provide a coherent view of the ultraviolet sky, the data should be post-processed under a common framework. In 2017, the IAU working group on ultraviolet astronomy identified the need to define such a common framework for the upcoming ultraviolet missions, and coordinated the definition of a standard set of photometric bands that could serve for homogenizing the current and future data. This paper presents the procedure adopted by the working group for the definition of the standard photometric system, that was approved by the IAU during the General Assembly Business Sessions held in August, 2021. The photometric system consists of seven bands, denoted as UV1-UV7, all included in the range 115 - 400 nm. Some of these bands are based on existing filters, while others have been defined as theoretical bands with constant throughput. This system is to be regarded as a set of synthetic bands for post-processing the data of any mission, and an example of its application to the SPARCS cubesat is also included. The photometric bands are publicly available and can be downloaded from https://www.nuva.eu/uv-photometry/.
What are the “Purposes” of Buddhist Sūtras? From Vasubandhu’s Logic of Exegesis (Vyākhyāyukti)
Authors: Horiuchi Toshio 
Published: June 2023

AbstractAs its name implies, Vasubandhu’s Vyākhyāyukti (VyY) explains the logic or methodology (yukti) of exegesis or sūtra interpretation (vyākhyā) and only survives in a Tibetan translation. In recent years, research on this treatise has been gradually accumulating. However, due to the difficulty of the Tibetan translation, some of the arguments therein have been misunderstood. In this article, after reviewing the general framework of Vasubandhu’s method of interpreting the sūtras, I will present a newly discovered parallel regarding his discussion of the “purpose, prayojana” of the sūtras and reread it through a close philological examination of various sources in Sanskrit and Tibetan. Thus, this article will first elucidate the details of Vasubandhu’s explanation of the purpose of the Buddha’s preaching using synonyms and will clarify an aspect of his views on the Buddha’s word. In addition, concerning this “purpose,” I will elucidate the characteristics of the final chapter of this text, which provides stories about hearing the Buddha’s words with respect. By doing so, I would like to reveal the characteristics of the VyY as a manual for vivid preaching.