bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Role of Anti- Cathapsin G among Patients with Rheumatiod Arthritis
Authors: Al-Rubaye Mahmood R. , Abdul-Qader Sajid N. , Abdul–majeed Nahla G. , Kamil Leen K. M. 
Published: September 2023

Background: Perinuclear Antineutrophil Cytoplasmic Autoantibodies (pANCA) have been found in patients with rheumatiod arthritis. Cathepsin G was the major target antigen.The present study was to investigate the unknown target antigen of ANCA (Cathapsin G ) in patients with rheumatiod arthritis Objective: This study is to investigate the prevalence of anti-Cathapsin G and rheumatoid factor in Iraqi patients with rheumatiod arthritis.Patienties&Methods: From1st January until 30 June of 2011 fourty five rheumatiod arthritis patients referred to the immunological department in the teaching laboratory of medical city and twenty five apparently healthy individual used as a control group were investeged to rheumatic factor IgG, IgM ,IgA isotypes and anti-Cathapsin G were measured by using enzyme immunoassay technique.Result: This study showed that the age of patients with rheumatiod arthritis ranged between eigthen years and sixty six years with mean age of (36.08) , while the mean level for RF screen, RF IgG, RF IgM, RF IgA isotypes and anti-Cathapsin G were (160.71, 91.7, 136.64, 95.03 and > 9.2 ) respectively. There were 17(37.8%) males and 28(62.2%) females of RA patients. Immunologically, this study revealed that the serum RF screen was found more than 25 U/ml in all rheumatiod arthritis patients (100%, P: 0.0001 HS). On the other hand RF isotypes IgG ,RF IgM and IgA level were elevated more than 20 U/ml and it was detected in 31 (68.9%, P: 0.0001 HS), 31 (68.9%, P : 0.0001 HS) ,and 32 (71.1%, P: 0.0001 HS) patients respectively, while the rheumatiod factors (IgG,IgM, and IgA)were normal in healthy control group . Statistically RF screen has a highly significant association with RF IgG, IgM, and IgA (P= 0.0001). Anti-Cathapsin G was found in 12(26.7%, P value: 0.019) of patients with rheumatic arthritis patients. This study showed a association between the positive result of anti-Cathapsin G with RF IgG and RF IgM (35.5%, P: 0.047) the results were the same for both, while no association found with RF IgA (25%, P: 0.692).Conclusion: A significant correlation was found between anti-Cathapsin G and patients with rheumatiod arthritis and has a significant association with RF IgG and RF IgM while RF IgA had no relation with anti-Cathapsin G.
The levels of IFN- , IL-12 And Testosterone Hormone in Persons with Asymptomatic Toxoplasmosis
Authors: Abdul-Lateef Huda I. , AL-Najar Sabah A. , Abul Majeed Nahla G. 
Published: September 2023

Background: The primary goal of this study is to perceive the immunological differences in mean level of IFN- and IL-12 in persons who have positive results for anti-toxoplasma gondii antibodies compared to persons who gave negative results for these antibodies. The secondary goal is to inspect the endocrineimmune interaction in thesepersons by detecting the effect of testosterone hormone level on cellular immune response namely, IL-12& IFN- . This study also detect the effect of Toxoplasma gondii on the level of testosterone hormone in those persons compared with healthy control.Objective: Investigate the relationship between T. gondii and serum IL-12,IFN- and testosterone hormone levels in asymptomatic persons with positive anti-toxoplasma antibodies compared with healthy control and Study the endocrine _immune interaction in these persons .Patients and methods: Seventy seven asymptomatic persons who have positive anti-toxoplasma antibodies and 30 persons who have negative anti-toxoplasma antibodies were included in this study and subjected to estimating the levels of IL-12, IFN- and testosterone hormone by ELISA technique.Results: The levels of both IL-12 and IFN- were statistically higher in persons with positive antitoxoplasma antibodies than in control. The levels of testosterone hormone were higher in both males and females with positive toxoplasmosis than control. There was a positive association between increased level of testosterone and IL-12 level while there was no effectiveness of testosterone on IFN- level in persons with positive anti-toxoplasma antibodies.Conclusion: Toxoplasma gondii elicits cellular immune response detected by statistically important increased in IL-12 and IFN- level compared with control. Not only host hormone can affect responses to infection, but parasites can both enhance production and alter hormone concentration in their hosts.
Examine the association of nutrients, lifestyle, and related factors with the risk of depression in a well-nourished over-55-years old community
Authors: Shadmand Foumani Moghadam Mohammad Reza , Etemadi Sharif , Amushahi Mohammad , Araste Asie , Rashidipour Mina , Bakhshipour Reyhane , Jandari Sajedeh , Pezeshki Parnian , Rezvani Reza , Hosseini Zohreh 
Published: September 2023

BACKGROUND: The older adult population is increasing, and depression is commonly observed within this community. OBJECTIVE: Examine the association of nutrients and lifestyle with depression in a well-nourished over-55-years old community. METHOD: The risk of depression was evaluated by the Beck Depression Inventory. Lifestyle, health-related quality of life, and physical activity were assessed. Dietary nutrient intake was recorded and adjusted to body weight. RESULT: 58% of the population had mild to severe depression. The differences between depression groups for age, gender, quality of life, and nearly all social-economic factors were significant. The impact of age, physical activity, sports, economic level, and smoking on depression was independent of all other factors. Most adjusted nutrients and energy intake were inversely associated with depression (protein ( p = 0.043), fiber ( p = 0.037), iron ( p = 0.041), vitamin B6 ( p = 0.011), and caffeine ( p = 0.009) was independent of the energy intake). The predictor decision tree model for depression showed working in males and having sport, economics, and living with someone in females were the main depression predictors. CONCLUSION: Working for males and sports in females along with a high-quality lifestyle with a diet rich in protein, fibre, iron, vitamin B6, and caffeine were associated with a lower risk of depression in this population.
Features of the numerical modeling of the hydrogeological conditions of the soil massive during the excavation of the pit in the Plaxis software complex
Authors: Khoronzhevskyi Maksym , Miatko Maksym 
Published: September 2023

The construction of multi-storey civilian buildings, especially in the central districts of cities, is often accompanied by a developed underground part, which requires deep pits. The construction of such pits often leads to a change in the hydrogeological condition at and near the construction site.
This paper presents a comparison of the stress-strain state of the " base - pit enclosure" system, depending on the method of modeling hydrogeological conditions.
The study is divided into two stages: determination of the main features of the Plaxis software complex toolkit for modeling and determining pore water pressures; creating of numerical models and performing calculations. . The first part of the study describes the basic principle of determining stresses in saturated soils, pore pressure calculation types, hydraulic boundary conditions, and types of soil drainage.
In the second part of the study, the numerical models were developed in Plaxis 2D, based on the real object and hydrogeological conditions at the construction site. The two most popular methods for modeling hydrogeological conditions during dry excavation in the pit are described. A step-by-step calculation is performed taking into account the stages of excavation in the pit and dewatering and the construction of retaining structures according to the scheme provided by the design solutions.
The results of the calculations demonstrate the difference in the obtained values of forces and horizontal displacements of the retaining wall for models created using different methods of setting the hydrogeological conditions of the base.
In order to improve the accuracy of calculations and determine the impact of soil permeability, the impact of the stratigraphy of the base was excluded by solving theoretical problems with a homogeneous soil massif composed of clay or sandy soil with groundwater filtration rates in a wide range (kx=ky=0.001...6m/day). Based on the results obtained, it was found that both methods correlate with each other in the case of the presence of poorly filtering soils with a filtration coefficient of k=0.001...0.05 m/day, the calculations demonstrated similarity in the displacements and forces of the retaining wall in such schemes up to 97.9-99.9%. Instead, in the case of soils with high water permeability (k=0.4...6 m/day), the difference in results is up to 56.5%.
The practice of arranging a pit deeper than the level of the soles of the foundations of the surrounding buildings
Authors: Vynnykov Yuriy , Akopian Mkrtich 
Published: September 2023

A rational constructive-technological decision to arrange a fence of a deeper pit for a new building than the depth of laying strip foundations of the surrounding buildings has been substantiated and tested in practice. The decision to arrange the fence was tested based on the results of complex experimental and theoretical studies under the conditions of a wet loess massif. At same time, regulatory restrictions on additional subsidence of these buildings foundations are provided. It has been proven that the additional subsidence of existing objects did not exceed the permissible values according to the norms. This happened due to the arrangement of the pit fence, the phasing of soil extraction in the initial stages under of the soil berm protection. The technology provided for the construction of a pit fence with sheet piling (I-beam No. 30) with a step of 1 m, with timber lagging between them. Then they installed the capping beam, struts, rakers and gradually raised the floor and outer wall of the parking lot of the new building.
The results of long-term geodetic observations of the foundations deformations of buildings located in the zone of the pit influence of the new building at various construction stages of its enclosure are described.
Sufficient convergence of the simulation results in the plane condition using the FEM and field studies was determined (the relative error did not exceed 20%). An elastic-plastic soil model of the "basement - foundations of an existing building - pit enclosure" system was used for modeling.
The article describes examples of the results of FEM modeling of soil massif deformations at various stages of pit fence construction.
It was determined that during construction the largest horizontal movements of the pit fence vary from 8 to 23 mm in the area of existing buildings.The maximum vertical movements of the bases foundations of these buildings amounted to 10 mm, which does not exceed the permissible values according to the norms.
Prospects for further research on assessing the level of reliability of the pit enclosure by determining the variability parameters of the components of the system "foundation - foundation of the existing building - pit enclosure" have been determined.
Evaluation of the influence of the pile cap’s spatial rigidity on the stress-strain state of pile foundations of the building
Authors: Zhuk Veronika , Aloshkina Oleksandra , Piatkov Oleksandr 
Published: September 2023

Providing citizens with housing is one of the urgent problems in Ukraine. The limited number of floors allows the use of such an architectural and planning solution for open-type city blocks (internal areas with such planning remain more open and transparent, create a feeling of free space). In order to solve this problem, first of all, it is necessary to make structurally correct and economically reasonable solutions at the stage of building design, because 60...70% of the building price is the cost of structures and materials.
The main task of the designer is to develop structures for the safe and efficient operation of the building. These factors depend on the correctness of the development of the structural scheme of the building and the correctness of the calculation. The development of modern technologies and the availability of various calculation software complexes make it possible to perform such calculations. They make it possible to take into account the interaction of the elements of the "soil base – foundation - above-ground structures" system, which is mandatory for a modern level of design.
Computer modeling with the use of various software complexes allows us to monitor the formation of the stress-strain state in the load-bearing structures of the building depending on the deformation properties of the soil base on the construction site, also depending on the change in the parameters of the structures of the building itself. A comprehensive analysis of the initial data, a detailed study and analysis of the engineering and geological conditions of the construction site, taking into account the planning and construction scheme of the building, as well as performing a complex numerical study of the stress-strain state of the building elements allows to monitor the influence of changes in the parameters of the foundations on the redistribution of deformations and stresses in all structural elements of the building. Therefore, performing computer simulation makes it possible to choose a rational type of foundations that will have not only reliability requirements, but will also be cost-effective at the same time.
This article presents the results of a comparison of the options of a raft pile cap and a strip pile cap of the foundations on the stress-strain state of the foundation structures. The conducted research confirms that the transition from the strip pile cap option to the raft pile cap option causes a change in the subsidence character of the building. It is shown that the use of variable design of foundations makes it possible to design a reliable and at the same time cost-effective option of foundations. Based on the results of the study, the choice of a rational option of foundations was substantiated.
Trauma Healing Perawat Pada Korban Bencana Gempa Bumi Cianjur
Authors: Rahmawati Ratu Dini , Habibi Rahman Fauzan , Juleha Siti , Setiyawan Salsabila 
Published: September 2023

Bencana alam merupakan peristiwa luar biasa yang mengganggu dan mengancam kehidupan manusia. Salah satu jenis bencana alam yaitu gempa bumi. Gempa bumi Cianjur terjadi pada 21 November 2022 pukul 13:21:10 WIB dengan magnitudo 5.6 SR yang menimbulkan kerusakan infrastruktur maupun korban jiwa. Selain akibat fisik, gempa bumi juga meninggalkan dampak psikologis bagi pengungsi sehingga diperlukan penanganan komprehensif dari berbagai pihak tak terkecuali perawat. Universitas Esa Unggul memiliki program studi jurusan keperawatan dan terpanggil untuk mengatasi masalah yang dialami para pengungsi. Metode pengabdian masyarakat dilaksanakan dengan mengirimkan tim relawan perawat kesehatan untuk memberikan layanan kesehatan dan trauma healing melalui edukasi, support emosional dan dukungan psikologis melalui layanan konsultasi pada pengungsi yang terdampak. Hasil kegiatan didapatkan keluhan fisik/ penyakit dapat diminimalkan dan kecemasan maupun depresi pengungsi dapat teratasi dibuktikan dengan pengungsi tampak senang dan ceria dan mau memanfaatkan layanan konsultasi yang di buat di posko pengungsi.
Realizing Inclusive Education in the Era of Industry 4.0: The Role of the PTPN IV Dolok Ilir School Website
Authors: Tulus  , Marpaung T.J. , Suriati  
Published: September 2023

Inclusive education has become an increasingly important aspect in addressing the dynamics of the industry 4.0 era. To realize inclusive education at PTPN IV Dolok Ilir School, the utilization of digital technology, particularly the school website, is being employed. Inclusive education aims to provide equal and sustainable access to education for all students, including those with special needs. The application of technology in the form of a school website has opened up broader access for students, parents, and educational stakeholders. In the context of PTPN IV Dolok Ilir School, this website serves as an information hub providing a variety of learning materials, schedules, announcements, and interactions among teachers, students, and parents. Furthermore, this website system ensures high transparency in facilitating better communication between the school and students' families. The key role of digital technology in assisting in the creation of an inclusive educational environment at PTPN IV Dolok Ilir School results in increased access to education, student empowerment, and greater parental involvement in supporting their children's educational development. The broader implications of this approach include a positive contribution to the quality of education in an era dominated by technological change and ensuring that no student is left behind in reaching their full potential.
The restructuring of food systems: Trends, research, and policy issues
Authors: Koc Mustafa , Dahlberg Kenneth A. 
Published: September 2023

<p>This issue brings together a selection of articles based on presentations at two Conferences in 1997. The aim has been 1) to offer clearer and more understandable descriptions of the major trends and relationships that are involved in the structural transformations that are occurring in food systems at all levels; 2) to help develop better theoretical and conceptual tools to aid us in analyzing such restructurings and their dynamics; and 3) to clarify a number of practical issues facing those seeking to promote more sustainable and just food systems, especially at the local level. With only one exception, all the articles here focus on Western economies where food systems are highly commodified, globally integrated, corporate, and state structures have been restructured by a series of neo-liberal reforms in recent years. In pointing out the problems with these food systems, the articles also discuss various possibilities for structural reforms for more healthy, sustainable, just, and equitable food systems and societies. </p>
Prospective Analysis of Percent Free Prostate-Specific Antigen as a Better Predictor of Early Diagnosis of Prostate Cancer
Authors: Islam Md Azizul , Haque Md Jawadul , Hossain Md Mokter , Islam SM Shahinul 
Published: September 2023

Prostate-Specific Antigen (PSA) is a prostate cancer tumor marker, but furthermore, studies have revealed that many people with benign prostatic issues or other conditions have high PSA levels in their blood. As a result, various approaches have been suggested to boost prostate-specific antigen specificity. The aim of the study to determine whether the free-to-total PSA ratio (percent fPSA) is able to be utilized to discriminate between prostate cancer and benign prostatic hyperplasia. From December 2018 to November 2022, 260 males with Lower Urinary Tract Symptoms (LUTS) symptoms attended Rajshahi Medical College Hospital in Bangladesh were recruited purposively for a cross sectional study as per inclusion criteria. Digital Rectal Examination (DRE) and transrectal ultrasonography were performed along with age analysis. Before any manipulation, total PSA, free PSA, and percent free PSA were assessed. Transrectal ultrasound-guided biopsy or digitally guided biopsy was used to confirm the diagnosis. SPSS 26 was used to analyze the data. Among the 260 individuals, 105 were diagnosed with prostate cancer and the remaining 155 were diagnosed with benign prostatic hyperplasia. Patients with CaP were much older than those with Benign Prostatic Hyperplasia (BPH) (Mean±SD was 72±4.4 vs. 64±6.6 years, respectively) (p = 0.00001). The sensitivity, specificity, and positive predictive value of % free PSA (at cut off point 0.16) were greater (94%, 93%, 90% respectively) than those of total PSA (84%, 48%, 52% respectively). The proportion of false positives was lower in percent free PSA (10%) than in tPSA (19%). All of these considerations are critical in establishing the appropriateness of a screening test. In case of percent free PSA, the overall accuracy was 93%, significantly higher than tPSA (62%) (p<0.005). Thus, the free/total/ serum PSA ratio assists more accurately in differentiating BPH from prostate cancer. When compared to tPSA, the fPSA/tPSA and ratio enhance the discrimination between BPH and CaP comparable and are equally beneficial in lowering the incidence of unnecessary biopsies, but tPSA alone has less impact.
J. Bio-Sci. 30(2): 67-77, 2022
Historical Coincidence or Generic Cross-Pollination? The Angry Hills and the Birth of Film Noir in Greece
Authors: Tzioumakis Yannis 
Published: September 2023

In the late 1950s and early 1960s Greek cinema saw the release of a number of films with many noir characteristics that critics and scholars have retrospectively identified as a Greek noir film cycle. While their status as films noirs in Greece has been debated in some depth, this chapter focuses on the UK-US production The Angry Hills (1959) that was shot on location in Greece around the same time, with a view to determining whether it was an inspiration for that film cycle. Directed by Robert Aldrich and written by A.I. Bezzerides (who had previously collaborated in the celebrated noir Kiss Me Deadly [1955]), The Angry Hills was a curious hybrid of a war film, a spy thriller and a melodrama that was also characterised by strong noir elements, stylistically and thematically. The chapter examines the film’s engagement with noir, before exploring the intriguing possibility that the presence of Aldrich and Bezzeridis in Greece and their engagement with local crafts and talent became a material influence on the Greek noir cycle that followed.
Harlem’s Bible Stories: Christianity and the New Negro Movement
Authors: Pinkerton Steve 
Published: September 2023

In the past, scholarly efforts to situate the Harlem Renaissance as a modernist enterprise tended to downplay the movement’s religious contexts and the religious themes that pervade its art and literature. This was a strategic, even necessary move for such scholarship—given that modernism itself was conventionally deemed an inherently secular project, predetermined by God’s supposed death in the previous century. Recent reappraisals of modernism’s religious underpinnings, however, suggest other ways of understanding the modernism(s) of the ‘New Negro’ movement. Exploring both the religious and the modernist dimensions of the Harlem Renaissance, this chapter examines how each of these dimensions informs the other in works by Langston Hughes, Countee Cullen, Zora Neale Hurston, and Richard Bruce Nugent.