bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efficacy and safety of totally laparoscopic gastrectomy with Uncut Roux-en-Y for gastric cancer: A dual-center retrospective study
Authors: Chen Yizhen , Zheng Yuanyuan , Tan Song , Chen Yifan , Zheng Tao , Liu Shaolin , Mi Yulong , Lin Shentao , Yang Changshun , Jiang Jian , Li Weihua 
Published: July 2023

Abstract

Background Uncut Roux-en-Y (URY) effectively alleviates the common complications associated with RY, such as Roux-en-Y stasis syndrome (RSS). However, for gastric cancer (GC) patients, it is still controversial whether URY has an impact on long-term prognosis and whether it has fewer input loop recanalization. Therefore, compare whether URY and RY have differences in prognosis and long-term complications of GC patients undergoing totally laparoscopic gastrectomy (TLG). Methods We analyzed the data of patients who underwent TLG combined with digestive tract reconstruction from dual-center between 2016 and 2022. Only patients undergoing URY and RY were selected for analysis. Progression-free survival (PFS) and overall survival (OS) were estimated. Bias between the groups was reduced by propensity score matching (PSM). The Cox proportional hazard regression model was used to further analyze the influence of URY on prognosis. Results 242 GC patients were enrolled (retrospectively registered: IRB-2023-202). The URY had significantly shorter operation time, liquid food intake time, and hospital stays than the RY (P < 0.001). The URY had fewer long-term and short-term postoperative complications than the RY, especially with regard to RSS, reflux esophagitis, and reflux gastritis. The 3-year, and 5-year OS of the URY group and the RY group before PSM: 87.5% vs. 65.6% (P < 0.001), and 81.4% vs. 61.7% (P = 0.001). PSM and Cox multivariate analysis confirmed that compared to RY, URY can improve the short-term and long-term prognosis of GC patients. Conclusion TLG combined with URY for GC, especially for advanced, older, and poorly differentiated patients, can promote postoperative recovery, and improve long-term prognosis.
Global burned area increasingly explained by climate change
Authors: Burton* Chantelle , Lampe* Seppe , Kelley Douglas , Thiery Wim , Hantson Stijn , Christidis Nikolaos , Gudmundsson Lukas , Forrest Matthew , Burke Eleanor , Chang Jinfeng , Huang Huilin , Ito Akihiko , Kou-Giesbrecht Sian , Lasslop Gitta , Li Wei , Nieradzik Lars , Li Fang , Chen Yang , Randerson James , Reyer Christopher , Mengel Matthias 
Published: July 2023

Abstract

Fires are now raging longer and more intensely in many regions worldwide. However, non-linear interactions between fire weather, fuel, land use, management, and ignitions so far impeded formal attribution of global burned area changes. Here we show that climate change is increasingly explaining regional burned area patterns, using an ensemble of global fire models. Climate change has increased global burned area by 16% for the period 2003–2019, and raised the probability of experiencing months with above-average global burned area by 43%. Climate change-induced burned area increased in most regions, including those recently struck by extreme fire like Australia, South America and Siberia. Moreover, the contribution of climate change to burned area is rising by 0.22%year− 1 globally, with the largest increase in Central Australia (2.5%year− 1). Our results highlight the importance of immediate, drastic and sustained greenhouse gas emission reductions to stabilize fire impacts on lives, livelihoods and ecosystems.
Improving the effect of radiation therapy by inducing reoxygenation of lung cancer cells through aerobic exercise
Authors: Jeon Jaewan , Park Geumju , Do Hwan-kwon , Kang JiHoon , Jo Sunmi , Youn BuHyun 
Published: July 2023

Abstract

In the field of radiation therapy, the oxygen effect is the most important key factor in increasing the treatment efficiency. Many researchers have studied methods for causing reoxygenation inside tumor cells. This study was conducted to determine whether reoxygenation is induced through relatively accessible aerobic exercise. The animals were injected with 5×105A549 cells in the flank and tumors were allowed to develop. Upon identification of a palpable tumor (tumor volume of 200 mm3), radiation and aerobic exercise combined treatment was administered for 2 weeks. Radiation was irradiated immediately after performing aerobic exercise. Radiation was irradiated with 2 Gy to the tumor and aerobic exercise was performed at a speed of 8.0 for 30 minutes. Next, 4–6 µm sections were prepared and stained with hematoxylin and eosin (H&E) following standard procedures. For Ki-67 and CA IX, HIF-1α, 4-hydroxynonenal & nitrotyrosine immunohistochemistry. We confirmed that lung cancer cell growth was suppressed when aerobic exercise was combined with radiotherapy throughin vivoxenograft studies. In addition, the effect of aerobic exercise on the radiation therapy effect through reoxygenation in tumor cells was confirmed. We also confirmed that HIF-1α and CA IX expressions were significantly increased in the combination treatment group. Lastly, we performed transcriptome analysis to discover the key factors that aerobic exercise induces reoxygenation. Taken together, the results suggest that the effect of radiation therapy is enhanced through aerobic exercise, which is relatively easy to apply.
Utilization of carica papaya seeds as natural coagulants for turbidity removal from wastewater
Authors: Hosseini Morteza 
Published: July 2023

Abstract

In this research, turbidity was eliminated using the natural coagulant Carica papaya. Using wastewater from an industrial park in Mazandaran, Iran, and a salt solution of NaCl, this investigation sought to improve the coagulant efficiency. The greatest amount of turbidity clearance was determined by examining the effects of pH and coagulant dosage. After 30 minutes of treatment, the use of Carica papayaseeds at the recommended dosage of 200 mg/L resulted in the greatest turbidity reduction effectiveness of 89%. Under ideal circumstances, alum concentrations of 100 mg/L and Carica papaya seeds concentrations of 100 mg/L after 30 minutes of treatment, dual flocculation of Carica papaya seeds and alum had a synergistic effect, resulting in a maximum turbidity reduction of 95%. Utilizing response surface methodology (RSM) based on a central composite design (CCD), the coagulation-flocculation (CF) process was improved. On the elimination of turbidity, the impacts of three parameters, contact time, pH, and natural coagulant dosage were assessed. The flocculation process was clarified by the use of scanning electron microscopy (SEM) and Fourier transform infrared (FTIR) investigations. The findings showed that the active components of Carica papaya seeds, such as proteins, polysaccharides, and fiber, contribute to their capacity to coagulate turbidity.
What Factors Influence the Shaping of Urban Public Spaces for Sports Cities? A Systematic Review
Authors: Al-Taesh Najmaldin , Ujma-Wąsowicz Katarzyna 
Published: July 2023

Abstract
In recent years, the concept of developing sports cities has gained popularity and become a notable trend. Urban public spaces have played an important role as suitable venues for informal sporting activities in cities. Policymakers and scholars have come to realize that an aesthetically pleasing and well-designed public space can encourage and increase participation in sports. This systematic review aims to identify the factors that influence the shaping of public spaces for sports cities accessible to all. Ten electronic databases were searched to identify relevant studies published between 2010 and 2022. The data were independently assessed and extracted by two reviewers. Full-text copies of 68 articles were read, and 24 articles meeting the inclusion criteria were included in this review. A synthesized descriptive analysis of the data was then performed. The results of this review identified factors that influence the shaping of urban public spaces for sports cities, including spatial sports facilities, organizational and programmatic factors, and environmental factors. Some factors can facilitate sports and physical activity, while others may act as barriers and have a negative impact on participants. This study recommends summarizing the policy and practice implications of these results for promoting sports cities to address these barriers and make sporting activities more accessible to all.
Modern Trends of Organization of the Underground Urban Space
Authors: Praslova Valentyna , Riabets Yuliia 
Published: July 2023

Abstract
The article is devoted to important issues of perspective modern organizational tendencies of underground urban space. Innovative world experience of organization of underground space and its use by creating underground buildings and structures for optimal working, living, recreation and movement of the urban population, increasing the area of open green spaces on the surface, creating a comfortable and aesthetically attractive urban environment are reviewed. The ecological, economic, political and cultural features that influence the formation and development of underground space in terms of sustainable development are analyzed. The architectural and spatial structure and functional features of underground permanent cities are considered. The basic modern tendencies of the organization of underground urban space are defined in the town-planning architectural-spatial, functional aspects and aspects of sustainable development.
Photocatalytic Decolourization of Rhodamine B by Modified Photo-Fenton Process with Quasicrystals – Preliminary Research
Authors: Łoński Sylwester , Łoński Wojciech , Babilas Rafał , Barbusiński Krzysztof 
Published: July 2023

Abstract
A novel photocatalytic process using a modification of photo-Fenton reaction, with sodium percarbonate (SP), as an alternative source of H2O2, and alloy Al65Cu20Fe15 containing, among others, quasicrystals (of the percentage composition Al65Cu20Fe15), being a source of iron ions, effectively decolourizes the aqueous solution of rhodamine B (RB; solution of 5 mg/l). The source of UV radiation was a lamp with a power of 36 W. The experiments were carried out at pH = 7 and reaction time (from 5 to 60 min). The increase in SP concentration (in the range of 8.3 to 33.3 g/l) significantly increased the degree of degradation of RB and the reaction rate. However, the use of quasicrystals, in the range of 8.3 to 33.3 g/l, was also important in the modified photocatalytic photo-Fenton process. The best degradation effects of RB (95%) were obtained for the highest SP concentration of 33.3 g/l and the lowest quasicrystal concentration of 8.3 g/l. On the other hand, visual decolourization of RB was obtained with an efficiency of 70% for SP and quasicrystal concentrations of 16.7 g/l and 16.7 g/l, respectively, after 45 minutes, and for SP and quasicrystal concentrations of 33.3 g/l and 8.3 g/l, respectively, after the time of 20 minutes. The best RB degradation effects in the comparative method (UV/Na2CO3·1.5H2O2 without the addition of quasicrystals) were only 52.7%. The obtained results encourage further research to optimize the conditions of the proposed method and to investigate its applicability to other types of dyes and pollutants.
Levenberg-Marquardt backpropagation neural network procedures for the consumption of hard water-based kidney function
Authors: Sabir Zulqurnain , Umar Muhammad 
Published: July 2023

Abstract
Water resources in Nusa Tenggara Timur have great concentrations based on magnesium and calcium ions thus being referred to as “hard water”. Prolonged hard water consumption has become a reason of kidney disfunction that can cause additional illnesses, like cerebrovascular pathologies and diabetes. Hence, it is crucial to comprehend how drinking hard water affects renal functions. The current study shows the kidney dysfunction model based on hard water consumption by applying the stochastic procedures of the Levenberg-Marquardt backpropagation neural networks (LMBNNs). The kidney dysfunction model of hard water consumption depends upon human components and water. Human dynamics is further divided into susceptible, infected and recovered, while water components are categorized into calcium and magnesium concentration. The log-sigmoid transfer function along with 20 hidden neurons is used to present the solutions of the model. Three cases of the model have been numerically stimulated and the correctness of the stochastic technique is perceived by using the comparison of proposed and reference Adam databased solutions along with the negligible absolute error. Training, validation and testing performances have been applied to reduce the values of the mean square error. Moreover, the statistical performances using the transition of state, error histograms and regression/correlation have been validated to authenticate the reliability of the scheme.
The analysis of exact solitons solutions in monomode optical fibers to the generalized nonlinear Schrödinger system by the compatible techniques
Authors: Bilal Muhammad , Haris Hamza , Waheed Abdul , Faheem Muhammad 
Published: July 2023

Abstract
In this research work, we employ the unified method, the extended sinh-Gordon equation expansion method (ShGEEM), and the extended rational sine-cosine/sinh-cosh method to derive the novel optical solitons solutions of the (2+1)-dimensional nonlinear dynamical conformable fractional generalized Schrödinger system in monomode optical fibers. We extract the optical soliton solutions in diverse forms like, dark, bright, combinations of dark-bright, periodic, and singular solutions, that are presented by trigonometric functions, and hyperbolic functions. The employed procedures are useful in order to clarify nonlinear partial differential equations (NLPDEs) and secure new exact solutions in addition to previously recovered ones. The accuracy of these answers has been verified for all extracted results using the Mathematica. The 3D surface plots, 2D line plots, and associated contour graphs are used to analyze the obtained solutions to visualize and support the theoretical conclusions using appropriate parameter values. The findings of this research demonstrate the efficacy of the approaches exploited in enhancing nonlinear dynamical behavior.
A self-repair history: compensatory effect of a de novo variant on the FANCA c.2778+83C>G splicing mutation
Authors: Persico Ilaria , Fontana Giorgia , Faleschini Michela , Zanchetta Melania Eva , Ammeti Daniele , Cappelli Enrico , Corsolini Fabio , Mosa Clara , Guarina Angela , Bogliolo Massimo , Surrallés Jordi , Dufour Carlo , Farruggia Piero , Savoia Anna , Bottega Roberta 
Published: July 2023

Introduction: Fanconi anemia (FA) is a genome instability condition that drives somatic mosaicism in up to 25% of all patients, a phenomenon now acknowledged as a good prognostic factor. Herein, we describe the case of P1, a FA proband carrying a splicing variant, molecularly compensated by a de novo insertion.Methods and Results: Targeted next-generation sequencing on P1’s peripheral blood DNA detected the known FANCA c.2778 + 83C &gt; G intronic mutation and suggested the presence of a large deletion on the other allele, which was then assessed by MLPA and RT-PCR. To determine the c.2778 + 83C &gt; G splicing effect, we performed a RT-PCR on P1’s lymphoblastoid cell line (LCL) and on the LCL of another patient (P2) carrying the same variant. Although we confirmed the expected alternative spliced form with a partial intronic retention in P2, we detected no aberrant products in P1’s sample. Sequencing of P1’s LCL DNA allowed identification of the de novo c.2778 + 86insT variant, predicted to compensate 2778 + 83C &gt; G impact. Albeit not found in P1’s bone marrow (BM) DNA, c.2778 + 86insT was detected in a second P1’s LCL established afterward, suggesting its occurrence at a low level in vivo. Minigene assay recapitulated the c.2778 + 83C &gt; G effect on splicing and the compensatory role of c.2778 + 86insT in re-establishing the physiological mechanism. Accordingly, P1’s LCL under mitomycin C selection preserved the FA pathway activity in terms of FANCD2 monoubiquitination and cell survival.Discussion: Our findings prove the role of c.2778 + 86insT as a second-site variant capable of rescuing c.2778 + 83C &gt; G pathogenicity in vitro, which might contribute to a slow hematopoietic deterioration and a mild hematologic evolution.
Sampling locations and processing methods shape fungi microbiome on the surface of edible and medicinal Arecae semen
Authors: Wei Guangfei , Xu Jia , Zhang Zhaoyu , Zhang Guozhuang , Chen Shilin , Dong Linlin 
Published: July 2023

IntroductionArecae semen, which is derived from the dried ripe seed of Areca catechu L., has been commonly used as one of the major traditional Chinese medicines (TCMs). Three types of crude herbal preparations, namely, raw Arecae semen (AS), Arecae semen tostum (SAS), and Arecae semen carbonisata (FAS), are available for different clinical applications in TCMs. Although aflatoxin contamination in Arecae semen has been reported preliminarily, only a few studies have been conducted on fungal contamination.MethodsIn this study, the presence of fungi on the surface of three Arecae semen (AS, SAS, and FAS) that collected from four provinces were investigated using high-throughput sequencing and internal transcribed spacer 2.ResultsResults showed that the phyla Ascomycota (75.45%) and Basidiomycota (14.29%) and the genera Wallemia (7.56%), Botryosphaeria (6.91%), Davidiella (5.14%), and Symbiotaphrina (4.87%) were the dominant fungi, and they presented significant differences in four areas and three processed products (p &lt; 0.05). The α-diversity and network complexity exhibited significant differences in the four sampling locations (p &lt; 0.05), with higher in Yunnan (Chao 1, 213.45; Shannon, 4.61; average degree, 19.96) and Hainan (Chao 1, 198.27; Shannon, 4.21; average degree, 22.46) provinces. Significant differences were noted in the three processed samples; and SAS group had highest α-diversity (Chao 1, 167.80; Shannon, 4.54) and network complexity (average degree, 18.32).ConclusionsIn conclusion, the diversity and composition of microbiome on the surface of Arecae semen were shaped by sampling location and processing methods. This work provides details on the surface microbiome of Arecae semen samples and highlights the importance of roles of origin and processing methods in microbiomes, ensuring drug efficacy and food safety.
The co-construction of a reading assessment measure with adults with Down syndrome: a meaningful literacy approach
Authors: Frizelle Pauline , O’Donovan Sean , Jolley Mary , Martin Lisa , Hart Nicola 
Published: July 2023

IntroductionThe need to develop appropriate measures of broad-based reading-related literacy skills for adults with Down syndrome has been highlighted in the literature. In this study we aimed to co-construct a valid and reliable assessment measure that can be used to document meaningful everyday reading, in adolescents and adults with Down syndrome.MethodsThe study was carried out in two stages. Stage 1 used an inclusive participatory design in which individuals with Down syndrome were research collaborators (n = 46). Items to be included in the measure were identified and ecological, face and content validity were established through an iterative process. In stage 2 we examined the reliability of the tool and explored potential relationships between meaningful reading score and (1) age, (2) receptive vocabulary, and (3) reading ability as measured by standardized assessments. In addition, we profiled what a pilot cohort of adults with Down syndrome read (n = 33) and how they experience reading in their everyday lives.ResultsResults showed that 46 items were generated for inclusion in the Meaningful Reading Measure (MRM). Our preliminary data showed that the tool has internal and external reliability and ecological and content validity. There were no associations between meaningful reading score and any of the other variables examined. There was considerable variability in items read (range 12–44) which reflected a broad range of reading practices. Adults with Down syndrome identified the importance of reading as a pleasurable activity and as something that aids learning.Conclusion:The MRM developed here can be used (1) as a reading intervention outcome measure to complement existing standardized tools, (2) to profile meaningful reading in adults with Down syndrome, (3) to guide reading module content, and (4) to capture change in adults’ perceptions of themselves as readers. Future work is needed to establish the tool’s sensitivity to change over time.
EDUKASI MANAJEMEN NYERI SENDI PADA LANSIA DI RW 14 KECAMATAN NANGGALO KOTA PADANG
Authors: Amelia Weny , Sunesni  , Viki Yusri  , Eka Putri Primasari  , Anggi Delvia Yunita  , Shifitri Ananti Dwi Putri  , Fadila  , Moh. Fadjri  , Heru Septiadi  , Yeni Gea  , Mike Soraya  
Published: July 2023

Latar Belakang: Lansia adalah penduduk yang memiliki resiko tinggi untuk terjadinya berbagai macam penyakit degeneratif. Salah satu penyakit degeneratif adalah asam urat (Arthritis gout). Asam urat (Arthritis gout) adalah hasil metabolisme akhir dari purin yaitu salah satu komponen asam nukleat yang terdapat dalam inti sel tubuh. Peningkatan kadar asam urat dapat mengakibatkan nyeri didaerah persendian. Nyeri sendi merupakan pengalaman subjektif yang dapat mempengaruhi kualitas hidup lansia. Teknik relaksasi otot progresif merupakan terapi yang terfokus untuk mempertahankan kondisi relaksasi yang melibatkan kontraksi dan relaksasi berbagai kelompok otot mulai dari kepala sampai kaki. Dengan Teknik ini maka akan meningkatkan kesadaran otot terhadap respon otot tubuh.
Metode: Metode pelaksanaan pengabdian kepada masyarakat ini yaitu dengan melakukan pemeriksaan asam urat dan melakukan edukasi manajemen nyeri sendi pada lansia di RW 14 Kecamatan Nanggalo pada hari Kamis, 1 Desember 2022, dimulai dari jam 09.00-12.00 WIB. Peserta adalah lansia yang berada di RW 14 Kecamatan Nanggalo. Pemberian edukasi dapat meningkatkan pengetahuan lansia dalam mengatasi nyeri sendi pada asam urat.
Hasil: Hasil pengabdian masyarakat ini dapat meningkatkan pengetahuan pada lansia terkait manajemen nyeri sendi pada penderita asam urat dibuktikan 90% dari lansia dapat mengulangi penjelasan terkait manajemen nyeri sendi pada lansia yang mengalami asam urat (Arthritis gout).
Alfred Kantorowicz, “réconciliateur” entre Est et Ouest
Authors: Guillon Laurence 
Published: July 2023

Den Osten und den Westen versöhnen : So könnten der Lebensweg und die geistige Laufbahn von Alfred Kantorowicz (1899-1979), Herausgeber der literarischen Zeitschrift Ost und West, zusammengefasst werden. Der Berliner Autor lehnte sich immer gegen die deutsche Teilung auf, die er als „widernatürlich“ bezeichnete. So befand er sich stets zwischen zwei Stühlen, zu bürgerlich für den kommunistischen Staat, zu sozialistisch für die Bundesrepublik. Auch wenn er doppelt so lange in der BRD (1957-1979) wie in der DDR (1947-1957) gelebt hat und wenn die Jahre, die er im Osten verbracht hat, relativ gut dokumentiert sind, bleibt dagegen sein Werdegang im Westen nach seiner Flucht 1957 eher unerforscht. In diesem Artikel wird versucht, anhand seiner autobiographischen Schriften wie seines Deutschen Tagebuches und seiner in der BRD veröffentlichten Essays diese zwei Jahrzehnte im Westen ans Licht zu bringen.