bluuebunny/crossref_metadata_2025_split huggingface dataset:
Un mundo post-pandemia: perspectivas para la creación de ejes de desarrollo regionales frente a un futuro incierto de la globalización.
Authors: Díaz Ligarda Juan 
Published: August 2023

La pandemia del Covid-19 ha transformado nuestras vidas, alterando significativamente la manera en que trabajamos, studiamos e interactuamos con las personas en todo tipo de actividad cotidiana. En casi todo el mundo, los Gobiernos implementaron cuarentenas masivas a fin de mitigar la propagación del virus, causando impacto devastador en la economía mundial. Gran parte de dicho impacto ha sido consecuencia de la propia naturaleza del mundo globalizado en el que vivimos, que no solo ha contribuido con la rápida expansión del virus, sino también con la agudización de la crisis económica, debido al elevado grado de interdependencia que existe entre las economías. La pandemia ha dejado experiencias aleccionadoras sobre la sostenibilidad a largo plazo de la globalización y los límites de la diplomacia multilateral en momentos de crisis. En ese sentido, también deberá ser vista como una oportunidad para llevar adelante un renovado modelo de esarrollo más sostenible y más resiliente, a través de la creación de ejes de desarrollo regionales.
Study of Inter-relatedness between Hepato-renal Indices and Essential Minerals during the Last Trimester of Pregnancy
Authors: Oyediran Oyewale Thomas , Oladiti Rashidat Abidemi , Joseph Gregory Uchechukwu , Iyanda Ayobola Abolape 
Published: August 2023

Purpose: Earlier on, it was reported that altered hepato-renal parameters and depletions of some nutrients co-existed at third trimester among the study participants. Yet the role low levels of nutrients played in altered hepato-renal axis (i.e. a possible association between the two) was not investigated. Even though liver is known for its physiologic importance in the metabolism of various metals and abnormal levels of certain elements also induce alterations in physiologic processes in specific organs. The study is aimed at investigating correlation between nutritional parameters (total protein, albumin, calcium, magnesium) and hepato-renal indices (alanine aminotransferase, aspartate aminotransferase, bilirubin, alkaline phosphatase, urea and creatinine) at the last trimester of pregnancy.
Study Design: This is a cross-sectional study.
Methods/Participants: Forty pregnant women in the third trimester (29 weeks to term) were recruited as test group while another group of 40 women (age-matched, non-pregnant) served as control. 5 mL of blood was collected and used for estimation of nutritional indices and hepato-renal markers. Information on birth weight was obtained. Data were analyzed using Pearson’s correlation coefficient. P≤ 0.05 was considered significant.
Results: Data obtained from the study revealed that there were no correlations between any nutritional marker and hepato-renal indices. Similarly, nutritional markers were not correlated with birth weight.
Conclusion: There is no indication that there is a relationship between abnormal nutritional markers and indices of nephro-hepatic activities in third trimester women that had earlier being reported to feature abnormal liver and kidney function.
The Ethnobotanical Investigation, Phytochemistry and Antioxidant Activity of a Medicinal Plant Recipe Directed against Candida albicans and Enterobacteria Stains Producing ESBL CTX-M-15 Type in Burkina Faso
Authors: Traoré Bibata , Bangou Mindiédiba Jean , Zongo Koudbi Jacob , Sombié Pierre Alexandre Eric Djifaby , Traoré Loé Victor , Ouoba Hermann Yempabou , Ouedraogo Georges Anicet 
Published: August 2023

Aims: The objectives are to carry out an ethnobotanical survey among traditional healers in order to choose the most recipe used in the treatment of vaginal candidiasis in cities of Burkina Faso followed by phytochemical quantification, antioxidant activity and antimicrobial of the best recipe.
Methodology: Ethnobotanical surveys were conducted in Bobo-Dioulasso and Dédougou by semi-structured interview amount traditional healers. The extracts were obtained by ethanolic and hydroethanolic maceration. Characterization of the secondary metabolites was revealed by the tests in tubes. Polyphenolic compounds contents quantification was done by spectrophotometry using Follin-Ciocalteu reagent, aluminum trichloride and vanilic acid. The antioxidant activity was evaluated by two methods: DPPH• and FRAP. The Minimal inhibitory concentration on Enterobacteria strains was determined by the dilution method and the minimal bactericidal concentration was determined by inoculation on agar. The susceptibility test of Candida albicans strains was carried out using the disc diffusion assay.
Results: In total, 52 traditional healers were surveyed with a predominance of men (75%) in the both cities. 38 recipes of medicinal plants have been obtained. Decoction is the most frequent method of preparation in Bobo-Dioulasso (87.5%) and in Dédougou (27.27%). The leaves (44%) and the bark of the trunk (31.82%) are respectively the most parts used of the plants. Colorimetric tests revealed the presence of compounds such as flavonoids, alkaloids, tannins and saponosides. The best results of quantification tests of total phenolics, flavonoids and tannins, were obtained with the hydroethanolic extract (80.27±20.27(mgEAG/10 mg); 0.27±0.01(mgEQ/10 mg) and 73.31±4.65 (mgEC/10 mg)). With antioxidant activity, the highest value was obtained with the DPPH radical inhibition method (85.59±0.001%). Minimal inhibitory concentration revelead that the highest value was 0.781 mg/ml and the best minimal bactericidal concentration was 3.123 mg/ml.
Conclusion: Phytochemical and biological analysis realized could be partially justified by the recipes used in the treatment of vaginal candidiasis.
The Effectiveness of Combining Ipratropium Bromide and Salbutamol for the Treatment of Acute Severe Exacerbation of Asthma in Children: A Literature Review
Authors: Aly Ehab Aly Kilany 
Published: August 2023

The most common symptoms of asthma include episodes of wheezing, shortness of breath, and cough. When a person develops asthma in their childhood, it is usually seen to arise as a consequence of hay fever or allergic rhinitis and eczema, or atopic dermatitis. Maternal factors during the prenatal period have been found to be responsible to some extent in some infants, however, the role of breastfeeding and other nutritional allergies as the causes of asthma stands out to be unclear and controversial. The maintenance therapy of asthma in children comprises the following options, which are recommended to be used symptom-wise and only after keeping all the safety guidelines in mind. The combination therapy has been found to be very useful in treating asthma and reducing the complications that arise due to it.
Effect of Weed Management Practices on Growth, Yield and Quality of Okra [Abelmoschus esculentus (L.) Moench]
Authors: Singh Dinesh , Singh Ram Batuk , Nirankar  , Singh Budhesh Pratap , Kumar Rupesh , Maurya Rajat , Singh Tribhuwan 
Published: August 2023

The present investigation entitled “Effect of weed management practices on growth, yield and quality of okra Abelmoschus esculentus (L.) Moench)” was conducted at Vegetable Research Farm, Chandra Shekhar Azad University of Agriculture and Technology, Kanpur during kharif season 2022. The experiment was laid out in Randomized Block Design with seven different treatments viz. T1 = Pre-emergence application of Pendimethalin @ 6 ml /L, T2= Post emergence application of Quizalofop-ethyl @ 0.040 kg/ha ,T3 = Pre-emergence application of pendimethalin @ 6 ml/L + one hand weeding at 40 DAS , T4 = Post emergence application of Quizalofop-ethyl @ 0.040 kg ha-1 at 25 DAS + one hand weeding , T5 = Pendimethalin @ 6 ml /L as pre-emergence + Quizalofop-ethyl @ 0.040 kg ha-1 at 25 DAS , T6 = Weed free check (Three hand weeding) 20, 40 and 60 DAS , T7 = weed check control replicated thrice. The result of the study revealed that at 30 DAS maximum plant height (30.96cm) was reported in treatment T3 : Pre-emergence application of Pendimethalin @ 6 ml/L + one hand weeding at 40 days of sowing whereas at 60 and 90 DAS maximum plant height (75.50 and 113.53 cm) was reported in T6 : Weed free check (Three hand weeding) 20, 40 and 60 DAS. Maximum number of branches per plant (4.60)at 60 DAS was found in T3 : Pre-emergence application of Pendimethalin @ 6 ml/L + one hand weeding at 40 DAS and 90 DAS maximum number of branches per plant (5.86) was reported in T6 : Weed free check (Three hand weeding) 20, 40 and 60 DAS. Maximum number of nodes (17.83 ) at 60 days after sowing was noticed in treatment T3 = Pre-emergence application of Pendimethalin @ 6 ml/L + one hand weeding at 40 DAS and 90 Days after of sowing maximum number of nodes () was in treatment T6 = Weed free check (Three hand weeding) 20, 40 and 60 DAS. Maximum Pod diameter( 1.74cm) , fruit weight (12.88gm ), pod length( 14.1cm) , number of pods per plant( 25.66 ) , pod yield per plant ( 304.73gm) , pod yield per hectare (16.91 t), TSS( 3.2 Brix), crude fibre (8.46%) and cholorophyll content (1.18 mg) and relative cholorophyll content (54.39) .
Utilization of Reproductive Health Services and Associated Factors among Youths in Mombasa County, Kenya
Authors: Yonge Shadrack A. , Opiyo Bob , Kibira Agnes W. , Sharma Rekha R. 
Published: August 2023

Background: Reproductive health has become a global concern that is either poorly understood or not fully appreciated among the youth. Access to reproductive health services is important for protecting youth from STIs and unwanted pregnancy problems.
Aim: The study sought to establish utilization of reproductive healthcare services and associated factors among youths in Mombasa County, Kenya.
Study Design: A descriptive cross-sectional study was carried out between August 2018 and January 2019.
Methodology: A self-administered, structured questionnaire was utilized to gather information. The information gathered was summarized using an SPSS database. The data was analyzed with SPSS version 22. Logistic regression was done to identify possible factors associated with reproductive health service utilization. p-value less than 0.05 was considered as a level of significance.
Results: A total of 384 youth participated in the study, including 200 (62.2% females and 184 (37.8%) males. The media was the main source of information for modern family planning methods 200 (50. 1%). The majority of users 326 (84.9%) sought contraceptives from pharmacies. 213 (55.5%) were utilizing modern contraceptives. HIV/AIDS risk perception was significantly associated with utilization of reproductive health services [COR=2.34, 95% CI: 2.19-5.34].The condom was the most used method 134 (34.9%). Having knowledge about reproductive health services [COR=2.87; 95% CI: 1.92-3.94] was positively associated with the outcome. Male respondents were three (3) times more likely to use condoms [OR = 2.86, 95% Cl: 1.82-4.91] than female respondents.
Conclusion: There was low uptake of contraceptive services among the youth who were sexually active. The condom was the most commonly used contraceptive. Strengthening urban healthcare systems is key to have equality and improve accessibility of FP services among the teenagers and young women.
Association of Restless Legs Syndrome with Glycemic Control and Psychological Status in Adults with Type 2 Diabetes: A Systematic Review
Authors: Alanazi Eman Mohammed , Alfaer Sara Abdullah , Alanazi Naif Mohammed M. 
Published: August 2023

Background: Evidence is still lacking regarding the association of restless leg syndrome (RLS) on glycemic control and psychological status in diabetic patients.
Aims: To summarize the evidence regarding the association of RLS with glycemic control and psychological status in adults with type 2 diabetes.
Methods: The literature search compassed all English-published studies from inception till the 21st of May 2023 on the electronic databases of MEDLINE/PubMed, Cochrane Library, Web of Science, and ProQuest. The search terms included “Diabetes Mellitus, Type 2” AND "restless legs syndrome”. We created a narrative synthesis for the outcomes and pooling of the glycated hemoglobin (HbA1c) levels.
Results: Sixteen studies were included. Pooling of the HbA1c levels showed a lack of significant differences between the RLS+ve and RLS-ve groups. Seven out of eight studies showed a significant decrease in sleep quality. Three studies assessed the quality of life and found a marked decrease in RLS+ve patients. Two studies out of four found a significant association of RLS with depression, while the other two found a non-significant increase with RLS.
Conclusion: There is no evidence that RLS in type 2 diabetic patients is associated with poor glycemic control. The evidence suggests that RLS is associated with a reduction in sleep quality and quality of life. The evidence is inconclusive regarding the association of RLS with depression due to the low number of studies. Physicians should be aware of the associated disorders with RLS in diabetic patients and endeavour to identify and alleviate them.
Comparative Analysis of Microleakage Associated with Various Endodontic Sealers: An in-vitro Study
Authors: Batra Diksha , Handa Aashish , Bhullar Kanwalpreet Kaur , Khurana Surbhi , Brar Rajdeep Singh , Khanna Mallika 
Published: August 2023

Introduction: The purpose of the root canal obturation is to provide a hermetic seal, that inhibits the microleakage and canal reinfection, thus the health of the periapical tissues can be preserved. It has been observed that the sealer used during endodontic therapy has a direct link with the longevity of the treatment and the occurrence of postoperative pain.
Aim: The goal of the present study was to assess microleakage in extracted teeth of four separate endodontic sealers (AH Plus, Sealapex, MTA Fillapex, and Ceraseal) using the dye penetration method.
Materials and Methods: In this in-vitro study, 84 freshly extracted single-rooted teeth were endodontically treated and obturated using four different sealers and divided into four groups along with two control groups based on the sealer used. Microleakage was checked in apical sections using the dye penetration method under the stereomicroscope.
Results: The maximum dye penetration was seen in Sealapex whereas the least microleakage was shown by Ceraseal endodontic sealer.
Conclusion: Maximum microleakage was seen with calcium hydroxide based (Sealapex) while the least microleakage was noticed in bioceramic based (Ceraseal) sealer group.
Quadratic Thermal Convection in Magneto-Casson Fluid Flow Induced by Stretchy Material with Tiny Particles and Viscous Dissipation Effects
Authors: Fatunmbi E. O. , Agbolade O. A. 
Published: August 2023

This investigation is based on the phenomenon of quadratic thermal convection in Magneto-Casson fluid flow induced by stretchy material with tiny particles and viscous dissipation effects. The study aims to understand and optimize the complex behaviour of fluid flow and heat transfer in this system, which has significant implications for engineering and industrial applications. The Magneto-Casson fluid, characterized by its non-Newtonian behaviour and yield stress, interacts with stretchy material and tiny particles, introducing unique flow characteristics and thermal properties. Viscous dissipation, resulting from internal friction, further influences the convective heat transfer process. Mathematical models are developed and solved by employing a numerical technique through the Runge-Kutta Fehlberg scheme coupled with the shooting method to investigate these phenomena comprehensively. The results are deliberated using several graphs on the dimensionless profiles. The results showed that there is a decline in the momentum boundary film as the magnetic field improves due to the effect of the Lorentz force. Also, an increase in the Casson fluid term raises the viscosity and thereby resists the fluid motion.
beneméritos de Santa Efigênia:
Authors: Antunes Andressa 
Published: August 2023

Nosso objetivo é analisar o envolvimento de indivíduos pardos com a devoção de uma santa africana, a Santa Efigênia, na Irmandade do Rosário dos Pretos do Alto da Cruz, em Vila Rica. A análise tem como base, especialmente, os documentos da tesouraria da confraria e o Livro dos Brancos, bem como as trajetórias de vidas e redes sociais de pardos da confraria. Percebemos que o investimento nas celebrações desta irmandade revela que o sodalício do Alto da Cruz elegeu a invocação de Santa Efigênia como símbolo principal de sua sociabilidade. Os irmãos pardos, aos quais nos referimos como beneméritos, tiveram atuação decisiva. O investimento votivo de pardos livres ou libertos na celebração de Efigênia tanto representou uma tentativa de demonstração de ascensão e prestígio social, a partir de uma comunidade negra, como, ao mesmo tempo, conferiu a esta solenidade um caráter de autonomia e mobilidade frente aos estigmas do escravismo.
Primary Care Continuity, Frequency, and Regularity Associated With Medicare Savings
Authors: Sonmez Dilara , Weyer George , Adelman Daniel 
Published: August 2023

ImportanceReducing Medicare expenditures is a key objective of Medicare’s transition to value-based reimbursement models. Improving access to primary care is an important way to reduce expenditures, yet less is known about how visits should be organized to maximize savings.ObjectiveTo examine the association between Medicare savings and primary care visit patterns.Design, Setting, and ParticipantsThis retrospective cohort study used data from a 5% sample of traditional Medicare claims from 2016 to 2019. Participants had at least 3 primary care visits with at least 180 days between the first and the last visit, were not enrolled in Medicare Advantage, did not have end-stage kidney disease, and were not institutionalized. Data were analyzed from June 2022 to April 2023.ExposuresPrimary care visit patterns: visit frequency, regularity, continuity of care.Main Outcomes and MeasuresSavings in Medicare expenditures; risk-adjusted Medicare expenditures, number of emergency department (ED) visits, and hospitalizations.ResultsAmong 504 471 beneficiaries (298 422 [59.16%] women; mean [SD] age, 74.26 [10.41] years), temporally regular visits with higher continuity were associated with the highest savings. For these patients, the savings increased with increasing visit frequencies, with peak savings observed at higher visit frequencies as clinical complexity increased. As regularity and continuity decreased, the association between savings and visit frequencies progressively inverted. The group with a regular and highly continuous pattern was associated with greater savings (175.87%; 95% CI, 167.40% to 184.33%; P &amp;lt; .001), lower risk-adjusted expenditures (−16.61%; 95% CI, –16.73% to –16.48%; P &amp;lt; .001), fewer risk-adjusted ED visits (−40.49%; 95% CI, –40.55% to −40.43%; P &amp;lt; .001), and fewer risk-adjusted hospitalizations (−53.32%; 95% CI, –53.49% to –53.14%; P &amp;lt; .001) compared with the irregular noncontinuous group.Conclusions and RelevanceIn this cohort study, savings in Medicare expenditures and improvements in acute care utilization were associated with visit frequency, regularity, and continuity in primary care in an interrelated fashion such that optimization of primary care visit patterns along each axis were associated with the largest improvement in outcomes. Demonstrating the magnitude and interdependence of these associations is useful for health care professionals and policymakers as Medicare continues its transition to value-based reimbursement models.
Three-month work-related musculoskeletal disorders assessment during manual lymphatic drainage in physiotherapists using Generic Postures notion
Authors: Gorce Philippe , Jacquier-Bret Julien 
Published: August 2023

Abstract

Objectives
The aim of this work was to quantify the postures and to assess the musculoskeletal disorders (MSDs) risk in physiotherapists repeating a manual lymphatic drainage (MLD) over a three-month period. The underlying hypothesis was that there would be Generic Postures (GP) that would be repeated and could be used to more simply describe repetitive and long-duration complex activities.

Methods
The posture of five physiotherapists performing five 20-min MLD at their workplace was captured by two cameras. From the recordings, the adopted postures were extracted every 5 s and quantified through 13 joint angles, that is, 6594 analyzed postures. Rapid Upper Limb (RULA) and Rapid Entire Body Assessment (REBA) were used to assess MSDs risks. A hierarchical analysis was used to define GP.

Results
Seven GP were identified through mean values and standard deviation. GP ergonomic assessment showed a low to moderate MSD risk (RULA between 3 and 6 and REBA between 2 and 7). High neck (&gt;20°) and trunk (&gt;15°) flexion were observed for all GP. High shoulder abduction and flexion (&gt;40°) were evidenced for GP3 to GP5. GP1 was the most used (34%) and presented the lowest ergonomic scores (RULA: 4.46 ± 0.84; REBA: 5.06 ± 1.75). GP3 to GP6 had frequency of between 10 and 20%. GP5, GP6, and GP7 obtained the highest ergonomic scores (RULA&gt;5; REBA&gt;7). All physiotherapists use different GP combinations to perform MLD.

Conclusion
MLD could be described as a combination of GP. Ergonomic analysis showed that MLD exposes physiotherapists to low at moderate MSD risks.
Chromosomal Aberrations in Cancer
Authors: Vander Weele David J. , McNerney Megan E. , Le Beau Michelle M. 
Published: August 2023

OverviewThe malignant cells of most patients who have leukemia, lymphoma, or a solid tumor have acquired clonal chromosomal abnormalities, the identification of which can aid in establishing the correct diagnosis and prognosis and in the selection of therapy. Today, our arsenal of approaches to characterize an individual's malignant disease combines pathologic evaluation, cytogenetic analysis, and molecular studies, typically focused on a few key genes. The advent of high‐throughput methods, such as next‐generation sequencing, capable of surveying the entire genome or large panels of cancer‐related genes, presents new options for a revolutionary change in the way we diagnose, characterize, and treat cancer. The vision for the future entails an integrated molecular profile, that is, chromosomal pattern, gene/miRNA expression, DNA methylation/epigenomic pattern, gene mutation status, and chemosensitivity of each patient's tumor, as well as predisposition to disease, facilitating the development of an individualized treatment plan with decreased toxicities and prolonged survival.
Herpesviruses
Authors: Cohen Jeffrey I. 
Published: August 2023

OverviewEight herpesviruses have been isolated from humans: two of these, Epstein–Barr virus (EBV) and Kaposi sarcoma‐associated herpesvirus (KSHV), are associated with human tumors. EBV has been detected in lesions from patients with post‐transplant lymphoproliferative disease, nasopharyngeal and some types of gastric carcinoma, Burkitt lymphoma, Hodgkin lymphoma, and certain other lymphoid tumors. KSHV is associated with Kaposi sarcoma, primary effusion lymphoma, and Castleman disease. Each of these viruses encodes proteins important for establishment of latency, transforming cells, and evading the immune system.