bluuebunny/crossref_metadata_2025_split huggingface dataset:
Representasi Nilai Multikultural dalam Desain Ornamen Songket “Kambang Cino” Koto Gadang
Authors: Akbar Taufik , Imelda Desra , Rahmanita Nofi , Yanuarmi Dini , Qomarats Izan 
Published: September 2023

Abstrak Visualisasi suatu karya seni dapat dipengaruhi oleh kondisi zaman yang terkait dengan seniman dan gejala sosio-kultural suatu masyarakat, termasuk seni ragam hias atau ornamen. Ornamen songket “Kambang Cino” Koto Gadang secara tidak langsung dapat mengungkapkan pandangan hidup masyarakat perajin sekaligus gejala sosio-kultural yang diduga kuat merefleksikan keberadaan nilai multikultural. Tujuan penelitian ini adalah untuk menjelaskan bentuk visual, gaya seni, makna sekunder, tema karya, makna intrinsik dan nilai simbolik dari ornamen songket “Kambang Cino” Koto Gadang. Penelitian dilakukan dengan metode kualitatif dengan pendekatan sejarah melalui teori ikonografi Erwin Panofsky. Hasil penelitian menunjukan bahwa visualisasi songket ini menggabungkan ornamen Minangkabau dengan ornamen khas budaya Cina yang bergaya fantasi. Ornamen pada songket ini bertemakan tentang manusia dan alam semesta (makrokosmos) yang bermakna tentang nilai toleransi, perdamaian dan kemakmuran. Ornamen songket “Kambang Cino” merupakan representasi simbolik dari nilai keberagaman dan keterbukaan atas keberadaan etnis sosio kultural yang multietnis dalam masyarakat Koto Gadang sebagai bagian dari masyarakat Minangkabau dan Indonesia. Kata Kunci: desain, Koto Gadang, multikulturalisme, nilai, tenun songket AbstractThe visualization of an artwork can be influenced by the conditions of the times, the ideology of the artist, and the socio-cultural phenomena of society, including ornaments. Koto Gadang's "Kambang Cino" songket weaving ornament can indirectly express the view of the craftsman, as well as socio-cultural phenomena that reflect multicultural values. This study aims to explain the visual form, style, secondary meaning, theme, intrinsic meaning, and symbolic meaning of the songket weaving ornament "Kambang Cino" from Koto Gadang. The research was conducted using a qualitative method with a historical approach through Erwin Panofsky's iconographic theory. The results indicated that the visualization of this songket weaving combines Minangkabau ornaments with typical Chinese culture ornaments in a fantasy style. This songket weaving ornaments have the theme of humans and the universe (macrocosm) with tolerance, peace, and prosperity values. The songket weaving ornament "Kambang Cino" is a symbolic representation of the diversity and open mind values of the multi-ethnic socio-cultural life in Koto Gadang society as part of the Minangkabau and Indonesian society. Keywords: design, Koto Gadang, multi-culturalism, songket weaving, values
PERFORMANCE OF STEEL FIBER EXTRACTED FROM OLD WASTE TYRES ON MECHANICAL PROPERTIES OF CONCRETE FOR RIGID PAVEMENT CONSTRUCTION
Authors: Firdawok Mesihib , Geremew Anteneh , Ayene Habtamu , Chala Galata 
Published: September 2023

The application of Waste Recycled Steel Fibers (WRSF) extracted from waste tyres in fiber-reinforced concrete production has great benefits in civil engineering. Thus, this creates a need to study the appropriate length and dosages of recycled steel fiber in fiber-reinforced concrete. In this experimental research, the effects of varying lengths (5cm and 10 cm) and dosages (1, 1.5, 2, 2.5, and 3%) of WRSF on various mechanical properties of fiber-reinforced concrete for rigid pavement construction were studied. The aggregates were taken from a stockpile, commercially available cement Dangote Ordinary Portland Cement (OPC), and potable water. Non-probable sampling techniques were adopted to collect extracted waste steel tyres. The quality test for sand (fine) and coarse aggregate satisfies the requirements specified in the ASTM. The concrete mix design was done in two categories; the first was a control mix concrete and the second was the experimental mix concrete with the addition of steel fibers with varying lengths (5cm and 10 cm) and dosages (1, 1.5, 2, 2.5, and 3%) of WRSF in concrete (percentages were determined by density for each fiber). The mix ratio of cement: sand: aggregate (1:2:3) with a constant water-to-cement ratio of 0.53 was used throughout this investigation. The outcome showed that the fiber fraction with 1.5% and 10cm of fiber had the maximum compressive strength which was 45.59 MPa, while for the fraction with 1% and 5cm of fiber, the maximum compressive strength was 43.85 MPa. The flexural strength had a maximum value of 5.88 MPa at 3% fiber content for 5cm fiber and 5.09 MPa at 3% for 10cm of fiber. The maximum tensile strength attained was 4.74 MPa and 3.50 MPa at 3% WRSF for 5cm and 10cm of fiber, respectively. The strain value had a maximum value at 3% for both 10cm and 5cm of fiber which were 0.53 and 0.6 respectively. The concrete strength which was obtained with the addition of steel fiber showed reasonable improvement in compressive, indirect tensile, and flexural strength. However, as the percentage of WRSF increased, the workability of concrete reduced.
Zircon U-Pb geochronology of the Lan Sang gneisses and its tectonic implications for the Mae Ping shear zone, NW Thailand
Authors: Lin Yu-Ling , Lee Tung-Yi , Lee Hao-Yang , Iizuka Yoshiyuki , Quek Long Xiang , Charusiri Punya 
Published: September 2023

The Mae Ping shear zone (MPSZ), a major shear zone trending NW-SE in Thailand, is responsible for the left-lateral displacement of the N-S Triassic-Jurassic granitoid and gneiss belt. This displacement is postulated to have contributed to Cenozoic extrusion tectonics. Within the Lan Sang National Park, the MPSZ exposes several intensely deformed lithologies, collectively known as the Lan Sang gneisses. These gneisses have attracted considerable attention for their potential to substantiate the extrusion model. However, the timing of the emplacement of the orthogneiss protolith is still debated. Moreover, the origin and distribution of the Eocene syn-shearing granodiorite within this shear zone are not well understood. To shed light on the magmatic history of the MPSZ, this study utilized zircon U-Pb geochronology to systematically investigate the Lan Sang gneisses. Our findings demonstrate that these gneisses can be categorized into paragneiss and orthogneiss groups. Paragneiss samples feature zircons displaying rounded detrital cores ranging from 3,078 to 450 Ma, with metamorphic rim overgrowth of ca. 200 Ma (most Th/U &lt;0.01). This indicates that their Paleozoic sedimentary protoliths experienced high-grade metamorphism during the Triassic-Jurassic Indosinian orogeny. On the other hand, zircon from orthogneiss samples shows that their magmatic protoliths were predominantly emplaced either around ∼200 Ma or within 45-32 Ma. The Eocene-Oligocene magmatism likely coincided with the proposed Eocene metamorphism. Since these samples were deformed by left-lateral shearing, the left-lateral motion of the MPSZ probably ended after 32 Ma. Eocene-Oligocene magmatic events have also been identified in granite, mylonite, and gneiss samples from other regions along the Sibumasu terrane, including the Three Pagodas, Klaeng, Ranong, Khlong Marui shear zones, and the Doi Inthanon area. The Eocene-Oligocene magmatism was likely linked with the movement of the shear zones and may be responsible for the regional cooling pattern. The spatial and temporal distribution of the Eocene-Oligocene magmatism within the Sibumasu terrane supports the hypothesis that the inward migration of magmatism in the overriding plate resulted from the shallowing of the Neo-Tethyan slab.
Pre-pregnancy body mass index and glycated-hemoglobin with the risk of metabolic diseases in gestational diabetes: a prospective cohort study
Authors: Wang Xinyue , Zhang Simin , Yu Wenlu , Li Guohua , Li Jinglin , Ji Jing , Mi Yang , Luo Xiaoqin 
Published: September 2023

BackgroundMetabolic diseases during pregnancy result in negative consequences for mothers. Pre-pregnancy body mass index (BMI) and late-pregnancy glycated-hemoglobin (HbA1c) are most important factors independently affecting the risk of gestational diabetes mellitus (GDM). However how both affect the combined risk of other metabolic diseases in women with GDM is unclear. The study aims to investigate the influence of pre-pregnancy BMI and pregnancy glycemic levels on other gestational metabolic diseases in women with GDM.MethodsPregnancies with GDM from January 2015 to December 2018 in the Xi’an longitudinal mother-child cohort study (XAMC) were retrospectively enrolled. Those without other metabolic diseases by the time of oral glucose tolerance test (OGTT) detection were finally recruited and divided into four groups by pre-pregnancy BMI (Underweight &lt;18.5kg/m2; Normal weight 18.5-23.9 kg/m2; Overweight 24.0-27.9 kg/m2; Obesity ≥28.0 kg/m2, respectively) or two groups by HbA1c in late pregnancy (normal HbA1c&lt;5.7%; high HbA1c≥5.7%). Multivariate logistic regression analysis was used to identify risk factors. Interaction between pre-pregnancy BMI (reference group 18.5-23.9 kg/m2) and HbA1c (reference group &lt;5.7%) was determined using strata-specific analysis.ResultsA total of 8928 subjects with GDM were included, 16.2% of which had a composite of metabolic diseases. The pre-pregnancy overweight and obesity, compared with normal BMI, were linked to the elevated risk of the composite of metabolic diseases, particularly pre-eclampsia (both P &lt;0.001) and gestational hypertension (both P &lt;0.001). Meanwhile, patients with high HbA1c had an obvious higher risk of pre-eclampsia (P&lt; 0.001) and gestational hypertension (P= 0.005) compared to those with normal HbA1c. In addition, there were significant interactions between pre-pregnancy BMI and HbA1c (P&lt; 0.001). The OR of pre-pregnancy BMI≥ 28 kg/m2 and HbA1c≥ 5.7% was 4.46 (95% CI: 2.85, 6.99; P&lt; 0.001). The risk of other metabolic diseases, except for pre-eclampsia (P= 0.003), was comparable between the two groups of patients with different HbA1c levels at normal pre-pregnancy BMI group. However, that was remarkably elevated in obese patients (P= 0.004), particularly the risk of gestational hypertension (P= 0.004).ConclusionPre-pregnancy overweight/obesity and late-pregnancy high HbA1c increased the risk of other gestational metabolic diseases of women with GDM. Monitoring and controlling late-pregnancy HbA1c was effective in reducing metabolic diseases, particularly in those who were overweight/obese before conception.
Nitric oxide, thyroglobulin, and calcitonin: unraveling the nature of thyroid nodules
Authors: Samardzic Vladimir S. , Macvanin Mirjana T. , Zafirovic Sonja S. , Obradovic Milan M. , Gluvic Zoran M. , Grubin Jasmina , Gao Xin , Essack Magbubah , Isenovic Esma R. 
Published: September 2023

BackgroundThyroid nodules (TN) are localized morphological changes in the thyroid gland and can be benign or malignant.ObjectiveThe present study investigates the relationships between biochemical markers in serum (s) and their homologs in washout (w) after fine-needle aspiration biopsy (FNAB) of the TN of interest and their correlation with cytology specimen findings.MethodsWe investigated the relationships between serum biochemical markers nitric oxide (NO), thyroglobulin (TG), and calcitonin (CT), their homologs in washout after FNAB of the TN of interest, and cytology findings of biopsy samples classified according to the Bethesda system for thyroid cytopathology in this study, which included 86 subjects.ResultsWashout TG (TGw) level positively correlates with the cytology finding of the biopsy. A higher level of TGw correlates with higher categories of the Bethesda classification and indicates a higher malignant potential. The levels of serum NO (NOs), serum TG (TGs), serum CT (CTs), and washout CT (CTw) do not correlate with the cytology finding of the biopsy, and the higher levels of washout NO (NOw) correspond to the more suspicious ultrasound findings.ConclusionThe findings of our study suggest that TGw and NOw could be used as potential predictors of malignancy in TN.
Potential plasma biomarkers at low altitude for prediction of acute mountain sickness
Authors: Guo Haoran , Wang Qi , Li Tao , Chen Jingwen , Zhang Chao , Xu Ying , Chang Qing , Li Hangyi , Sun Weiqiang , Han Ruidi , Wang Chi , Wang Chengbin 
Published: September 2023

BackgroundAscending to high altitude can induce a range of physiological and molecular alterations, rendering a proportion of lowlanders unacclimatized. The prediction of acute mountain sickness (AMS) prior to ascent to high altitude remains elusive.MethodsA total of 40 participants were enrolled for our study in the discovery cohort, and plasma samples were collected from all individuals. The subjects were divided into severe AMS-susceptible (sAMS) group, moderate AMS-susceptible (mAMS) group and non-AMS group based on the Lake Louise Score (LLS) at both 5000m and 3700m. Proteomic analysis was conducted on a cohort of 40 individuals to elucidate differentially expressed proteins (DEPs) and associated pathways between AMS-susceptible group and AMS-resistant group at low altitude (1400m) and middle high-altitude (3700m). Subsequently, a validation cohort consisting of 118 individuals was enrolled. The plasma concentration of selected DEPs were quantified using ELISA. Comparative analyses of DEPs among different groups in validation cohort were performed, followed by Receiver Operating Characteristic (ROC) analysis to evaluate the predictive efficiency of DEPs for the occurrence of AMS.ResultsThe occurrence of the AMS symptoms and LLS differed significantly among the three groups in the discovery cohort (p&lt;0.05), as well as in the validation cohort. Comparison of plasma protein profiles using GO analysis revealed that DEPs were primarily enriched in granulocyte activation, neutrophil mediated immunity, and humoral immune response. The comparison of potential biomarkers between the sAMS group and non-AMS group at low altitude revealed statistically higher levels of AAT, SAP and LTF in sAMS group (p=0.01), with a combined area under the curve(AUC) of 0.965. Compared to the mAMS group at low altitude, both SAP and LTF were found to be significantly elevated in the sAMS group, with a combined AUC of 0.887. HSP90-α and SAP exhibited statistically higher levels in the mAMS group compared to the non-AMS group at low altitude, with a combined AUC of 0.874.ConclusionInflammatory and immune related biological processes were significantly different between AMS-susceptible and AMS-resistant groups at low altitude and middle high-altitude. SAP, AAT, LTF and HSP90-α were considered as potential biomarkers at low altitude for the prediction of AMS.
Multi-pinhole collimator design in different numbers of projections for brain SPECT
Authors: Huang Wenbo , Mok Greta S. P. 
Published: September 2023

PurposeHigh resolution and sensitivity brain SPECT is promising for the accurate diagnosis of Alzheimer's disease (AD) and Parkinson's disease (PD). Multi-pinhole (MPH) collimators with a good performance in imaging small field-of-view (FOV) could be better used for brain SPECT. In this study, we aim to evaluate the impact of varying the number of pinholes and the number of projections on the performance of MPH brain SPECT.MethodsThe system design was based on a commercial clinical dual-head SPECT/CT scanner, with target spatial resolutions of 12 mm and 8 mm for AD and PD SPECT, respectively. In total, 1–25 pinholes were modeled for 64, 32, 16, 8, 4, and 2 projections. The 3D NURBS-based HUman Brain (NHUB) phantom was used in the analytical simulation to model99mTc-HMPAO and99mTc-TRODAT distributions. The 2D Derenzo hot-rod phantom and star phantom were used in Monte Carlo simulations to evaluate the spatial resolution and angular sampling performance of MPH. The influence of different detector positions was also evaluated for 2, 4, and 6 angular views. The projections were reconstructed using the 3D MPH ML-EM method. Normalized mean square error, coefficient of variation, and image profiles were evaluated.ResultsAlong with the decrease in the number of projections, more pinholes are required to achieve the optimum performance. For 32 projections, 9- and 7-pinhole collimators provide the best normalized mean square error (NMSE) to the coefficient of variation (COV) trade-off for99mTc-HMPAO and99mTc-TRODAT, respectively. Detector positions substantially affect the image quality for MPH SPECT for 2 and 4 angular views. The smallest rod size for the Derenzo hot-rod phantom, which could be resolved, is 7.9 mm for the MPH general purpose collimator (MPGP) with more than 16 projections and 6.4 mm for MPH high-resolution collimator (MPHR) with more than 8 projections.ConclusionThe number of pinholes affects the performance of the MPH collimator, especially when the projection views become fewer. More pinholes are required for fewer projections to provide better angular sampling in MPH for complex activity distributions. Detector positions affect the image quality of MPH SPECT for 2 and 4 angular views, where L-mode acquisition is slightly superior to H-mode. MPH collimators exhibited improved spatial resolution and angular sampling compared with both LEHR and single pinhole collimators.
Genetic determinants of Vitamin D deficiency in the Middle Eastern Qatari population: a genome-wide association study
Authors: Hendi Nagham Nafiz , Al-Sarraj Yasser , Ismail Umlai Umm-Kulthum , Suhre Karsten , Nemer Georges , Albagha Omar 
Published: September 2023

IntroductionEpidemiological studies have consistently revealed that Vitamin D deficiency is most prevalent in Middle Eastern countries. However, research on the impact of genetic loci and polygenic models related to Vitamin D has primarily focused on European populations.MethodsWe conducted the first genome-wide association study to identify genetic determinants of Vitamin D levels in Middle Easterners using a whole genome sequencing approach in 6,047 subjects from the Qatar Biobank (QBB) project. We performed a GWAS meta-analysis, combining the QBB cohort with recent European GWAS data from the UK Biobank (involving 345,923 individuals). Additionally, we evaluated the performance of European-derived polygenic risk scores using UK Biobank data in the QBB cohort.ResultsOur study identified an association between a variant in a known locus for the group-specific component gene (GC), specifically rs2298850 (p-value = 1.71 × 10−08, Beta = −0.1285), and Vitamin D levels. Furthermore, our GWAS meta-analysis identified two novel variants at a known locus on chromosome 11, rs67609747 and rs1945603, that reached the GWAS significance threshold. Notably, we observed a moderately high heritability of Vitamin D, estimated at 18%, compared to Europeans. Despite the lower predictive performance of Vitamin D levels in Qataris compared to Europeans, the European-derived polygenic risk scores exhibited significant links to Vitamin D deficiency risk within the QBB cohort.ConclusionThis novel study reveals the genetic architecture contributing to Vitamin D deficiency in the Qatari population, emphasizing the genetic heterogeneity across different populations.
Opportunities for high-energy neutron- and deuteron-induced measurements for fusion technology at the Soreq applied research accelerator facility (SARAF)
Authors: Mardor I. , Wilsenach H. , Dickel T. , Eliyahu I. , Friedman M. , Hirsh T. Y. , Kreisel A. , Sharon O. , Tessler M. , Vaintraub S. , Uhlemann F. V. 
Published: September 2023

The Soreq Applied Research Accelerator Facility (SARAF) will be based on a 40 MeV, 5 mA CW (continuous wave) proton/deuteron superconducting linear accelerator, currently under construction at Soreq Nuclear Research Center in Yavne, Israel. It is planned to commence operation during 2025. Experiments at SARAF could provide data on high-energy deuteron- and neutron-induced cross-sections, yields and radiation damage, which are invaluable for the design and operation of the International Fusion Materials Irradiation Facility-DEMO-Oriented NEutron Source (IFMIF-DONES), and fusion technology in general. Pulsed beams (∼1 nsec) of variable energy deuterons will irradiate a lithium target and generate pulsed neutron beams with energy up to ∼55 MeV, which will be used to measure energy-dependent neutron-induced differential cross-sections, utilizing time of flight techniques. Impinging continuous wave (CW) 40 MeV deuteron beams on a unique gallium-indium (GaIn) liquid-jet target, will generate a neutron rate of more than 1 × 1015 n/sec, with energies up to ∼45 MeV. We plan to use this high rate to measure integral neutron-induced reaction yields of all channels simultaneously, employing an original novel method that will identify the reaction-produced nuclei via accurate mass measurement. The neutron-energy dependence of the yields could be deduced by combining measurements at various deuteron energies. The measured cross-sections and yields at SARAF may predict the activation characteristics of construction materials of IFMIF-DONES and future fusion reactors. The deuteron beams will also be used directly to measure cross-sections via in-beam and offline methods. The high neutron and deuteron rates will extend SARAF’s reach to rare materials. The deuteron beam power density on the liquid GaIn target will be 100 kW/cm2(similar to IFMIF-DONES) on a 2 cm2spot. The resulting neutron flux on small secondary samples will be in the 1013 n/cm2/s level, only an order of magnitude less than IFMIF-DONES. Therefore, SARAF may serve as a pilot facility for fusion-related radiation damage studies, providing important information towards the design of IFMIF-DONES.
Inter-patient ECG heartbeat classification for arrhythmia classification: a new approach of multi-layer perceptron with weight capsule and sequence-to-sequence combination
Authors: Zhou Chenchen , Li Xiangkui , Feng Fan , Zhang Jian , Lyu He , Wu Weixuan , Tang Xuezhi , Luo Bin , Li Dong , Xiang Wei , Yao Dengju 
Published: September 2023

Objective: The objective of this research is to construct a method to alleviate the problem of sample imbalance in classification, especially for arrhythmia classification. This approach can improve the performance of the model without using data enhancement.Methods: In this study, we have developed a new Multi-layer Perceptron (MLP) block and have used a Weight Capsule (WCapsule) network with MLP combined with sequence-to-sequence (Seq2Seq) network to classify arrhythmias. Our work is based on the MIT-BIH arrhythmia database, the original electrocardiogram (ECG) data is classified according to the criteria recommended by the American Association for Medical Instrumentation (AAMI). Also, our method’s performance is further evaluated.Results: The proposed model is evaluated using the inter-patient paradigm. Our proposed method shows an accuracy (ACC) of 99.88% under sample imbalance. For Class N, sensitivity (SEN) is 99.79%, positive predictive value (PPV) is 99.90%, and specificity (SPEC) is 99.19%. For Class S, SEN is 97.66%, PPV is 96.14%, and SPEC is 99.85%. For Class V, SEN is 99.97%, PPV is 99.07%, and SPEC is 99.94%. For Class F, SEN is 97.94%, PPV is 98.70%, and SPEC is 99.99%. When using only half of the training sample, our method shows that the SEN of Class N and V is 0.97% and 5.27% higher than the traditional machine learning algorithm.Conclusion: The proposed method combines MLP, weight capsule network with Seq2seq network, effectively addresses the problem of sample imbalance in arrhythmia classification, and produces good performance. Our method also shows promising potential in less samples.