bluuebunny/crossref_metadata_2025_split huggingface dataset:
“Sleep Hygiene” untuk Kesehatan Fisik dan Mental yang Berkualitas yang Tinggal di Area Lahan Basah
Authors: Setyowati Anggi , Rahmayanti Devi , Agianto Agianto 
Published: August 2023

Ganggaun tidur rentan terjadi pada masyarakat yang sering mengalami bencana alam banjir. Masalah keperawatan yang berhubungan dengan gangguan tidur pada masyarakat di Desa Sungai Rangas Ulu, martapura Barat adalah insomnia (00095) berdasarkan NANDA International’s Nursing Diagnosis. Pendidikan kesehatan terkait sleep hygiene diperlukan untuk pencegahan insomnia dan menjaga kualitas tidur pasca bencana banjir. Program pengabdian masyarakat dilakukan pada bulan Maret 2023 dan memiliki tiga kegiatan utama, yaitu pengkajian, implementasi pendidikan kesehatan sleep hygiene, dan evaluasi kegiatan. Pengkajian dilakukan di awal kegiatan untuk merumuskan masalah dan menentukan strategi intervensi untuk menyelesaiakn masalah, kegiatan implementasi yaitu pendidikan kesehatan sleep hygiene dengan pendidikan kesehatan secara face to face, dan evaluasi kegiatan sleep hygiene dilakukan pada akhir kegiatan untuk mengukur pemahaman masyarakat. Sleep hygiene adalah manajemen perilaku dan lingkungan untuk mendapatkan kualitas tidur yang bagus dan mencegah gangguan tidur seperti menghindari kafein di malam hari, menghindari nikotin di malam hari, olahraga teratur, manajemen stress, mengurangi suara bising di kamar, pergi tidur dengan jadwal teratur, menghindari tidur siang lebih lama dua jam. Evaluasi pengabdian masyarakat adalah masalah keperawatan yang dialami oleh masyarakat desa adalah insomnia (00095) dengan etiologi ketidakadekuatan sleep hygiene, dengan data yang diperoleh masyarakat mengeluhkan bangun terlalu pagi, tidak puas dengan tidur, tidur siang lebih dari 2 jam, dan gangguan kesehatan, keadaan ini disebabkan juga akibat bencana banjir. Setelah dilakukan intervensi pendidikan kesehatan sleep hygiene, masyarakat memahami terkait manajemen tidur dan perilaku tidur yang benar.
Early Complications in the Era of ATRA Plus ATO Therapy Outside of Clinical Trials‐One Center Experience during Three Years and Literature Review‐
Authors: Alexandra Ghiaur , Doran Cristina , Ionescu Bogdan , Stancioaica Maria Camelia , Hirjan Roxana , Tatic Aurelia , Cirstea Mihaela , Dragomir Mihaela , Calugaru Onda , Popa Codruta , Jardan Cerasela , Vasilache Didona , Coriu Daniel 
Published: August 2023

Abstract
The hallmark of acute promyelocytic leukemia (APL) is the presence of the characteristic fusion transcript of the promyelocytic leukemia gene with the retinoic acid receptor α gene (PML::RARA), which is a molecular target for all-transretinoic acid (ATRA) and arsenic trioxide (ATO). Therapies with ATRA plus ATO have excellent outcomes in terms of complete remission rate, overall survival, and achievement of a deep and durable molecular response with a very low incidence of relapse. However, although the combination of ATRA and ATO has lower hematologic toxicity than standard chemotherapy, its use is associated with a spectrum of unique toxicities, such as hepatic toxicity, QTc (QT interval corrected) prolongation, neurotoxicity, and differentiation syndrome. Hematologists treating patients with acute promyelocytic leukemia should be aware of possible early-complications of the ATRA plus ATO regimen and aim to balance treatment-related adverse events and efficacy. Careful follow-up of the patient’s clinical course is essential to identify and treat each complication.
This study focused on treatment-related complications during induction and consolidations in patients with APL who received ATRA plus ATO. We retrospectively analyzed 26 adult patients diagnosed with APL between 2019 and 2022 at our center to identify the incidence rate, severity and time of onset of short-term non-hematologic adverse events relative to the initiation of the ATRA and ATO regimen. Additionally, we review the existing literature regarding the toxic side effects of ATO in APL and discuss how its most frequent toxicities should be managed. The median follow-up of our patients was 21.5 months (range, 1-48 months) and the most common adverse events were hepatic toxicity (69.2%), infections (46.1%), differentiation syndrome(23%) and QT prolongation (11.5%). All patients experienced at least one adverse event and grade 3 and 4 toxicities occurred in 57.6 % patients; these generally consisted of liver enzyme elevations, QTc prolongation, but also some rare manifestations such as musculoskeletal pain syndrome (1 patient) and ATO-related pancreatitis (1 patient). Most patients developed side-effects during induction.
This is the first study about Romanian patients diagnosed with APL. Our results suggest that all treatment-related adverse events, except for differentiation syndrome are manageable, self-limiting and reversible. All patients, except for two (one died during induction and one died during consolidation), were able to complete the treatment consolidation with ATO and ATRA.
Retinal Microvascular Alterations in a Patient with Type 1 Diabetes, Hemoglobin D Hemoglobinopathy and High Myopia – Case Report and Review of Literature
Authors: Dan Alexandra Oltea , Bălășoiu Andrei Teodor , Puiu Ileana , Tanasie Andreea Cornelia , Târtea Anca Elena , Sfredel Veronica 
Published: August 2023

Type 1 diabetes (T1D) is one of the most prevalent endocrinological diseases among children and young adults, with a growing incidence rate reaching up to 2.9 new cases per year per 100 000 persons below 15 years of age. We report the rare case of a 20-year-old female patient with T1D, hemoglobin D (HbD) heterozygote variant and high myopia of -10,00 spheric diopters and describe the retinal microvascular alterations visible on OCT angiography (angio-OCT). The patient also presented severe stature deficit (less than 3 standard deviations) and delayed puberty, which could not be explained only by suboptimal glycemic control, indicated a possible hypopituitarism. The HbA1c level evaluated with high performance liquid chromatography (HPLC) method was 6.5%, a falsely low value due to the HbD hemoglobinopathy. On ophthalmic evaluation the angio-OCT scan showed the following retinal microvascular alterations for the RE: the FAZ area vas 0.39 mm2, the FAZ perimeter was 2.88 mm and the circularity index was 0.58; for the LE: the FAZ area vas 0.34 mm2, the FAZ perimeter was 3.21 mm and the circularity index was 0.41. Clinicians should consider high performance retinal screening methods such angio-OCT evaluation for young T1D patients, especially for those with associated pathologies like high myopia and hemoglobinopathies. Moreover, multiple evaluation methods of the HbA1c values are mandatory as hemoglobinopathies can interfere with HbA1c assay methods accuracy.
The Influence of Emotional Intelligence, Teamwork, And Organizational Citizenship Behavior on Performance Agricultural Extension Workers in Banten Province
Authors: Sangadji Hamid 
Published: August 2023

Saat ini Indonesia khususnya Provinsi Banten sedang berada pada masa new normal, dimana semua organisasi, baik organisasi publik maupun private (swasta), dituntut untuk memiliki keunggulan bersaing agar mampu bertahan dan mandiri. Dinas Pertanian Provinsi Banten sebagai organisasi publik terbesar yang bergerak dalam bidang pelayanan penyuluh pertanian di Provinsi Banten (yang selanjutnya dalam penelitian ini disebut sebagai organisasi), memiliki tenaga penyuluh pertanian yang beragam kompetensinya, dituntut untuk memiliki keunggulan bersaing dan kinerja yang tinggi dengan tetap mengedepankan emotional intelligence, teamwork, dan organizational citizenship behavior yang baik, terutama dari tenaga penyuluh pertaniannya sebagai garda terdepan (gatekeeper) pelayanan penyuluh pertanian yang profesional, mandiri, berdaya saing, dan berjiwa wirausaha. Rumusan masalah dalam penelitian ini didasari dari latar belakang penelitian yang menyatakan pentingnya Kecerdasan Emosi (Emotional Intelligence), Teamwork, dan Organizational Citizenship Behavior bagi peningkatan Kinerja penyuluh pertanian di Provinsi Banten. Permasalahan penelitian ini yaitu, bagaimana meningkatkan Kinerja penyuluh pertanian di Provinsi Banten melalui peningkatan Kecerdasan Emosi (Emotional Intelligence), Teamwork, dan Organizational Citizenship Behavior. Secara garis besar tujuan penelitian ini untuk menguji dan menganalisis besarnya pengaruh Kecerdasan Emosi (Emotional Intelligence), Teamwork, dan Organizational Citizenship Behavior terhadap Kinerja penyuluh pertanian di Provinsi Banten. Kebaruan (novelty) dari penelitian ini yaitu belum ditemukan penelitian sebelumnya yang membahas tentang pengaruh Kecerdasan Emosi (Emotional Intelligence), Teamwork, dan Organizational Citizenship Behavior terhadap Kinerja penyuluh pertanian di Provinsi Banten, baik secara metode maupun aplikasi. Penelitian ini dilaksanakan di Dinas Pertanian Provinsi Banten, pada bulan Februari 2022 - Februari 2023. Populasi dalam penelitian ini yaitu seluruh penyuluh pertanian di Provinsi Banten yang berjumlah 650 orang. Sampel berjumlah 210 orang. Penarikan sampel dilakukan dengan metode simple random sampling yaitu sampel ditarik dari kelompok populasi secara acak dengan bantuan software Microsoft Excel. Penelitian ini termasuk dalam penelitian kuantitatif, dimana data diambil dengan metode penelitian survei, dan menggunakan kuisioner, lalu diuji dengan uji statistik, dan software program aplikasi SmartPLS Pro Versi 2.3.m3. Hasil penelitian menyatakan bahwa terdapat pengaruh langung positif Kecerdasan Emosi (Emotional Intelligence), Teamwork, dan Organizational Citizenship Behavior terhadap Kinerja penyuluh pertanian di Provinsi Banten.
Relationships between Work Environment and Employee Engagement mediate by Job Satisfaction
Authors: Simanjuntak Kemal H , Suhud Usep , Susita Dewi 
Published: August 2023

This research examines impact of work environment on employee engagement, and more that the role of job satisfaction as a mediator. We are empirically test relations between work environment and employee engagement mediate by job satisfaction in a national private bank in Indonesia.
The data from questionnaires on job satisfaction, work environment and employee engagement collected from s survey that we received from 893 respondent via online. The structural model is based on four construct, which tested using structural equation modelling (SEM) using IBM SPSS v25 and IBM AMOS v24.
An increase in work environment both positively relates to job satisfaction and employee engagement, and it shows also that job satisfaction mediate positively significant work environment to employee engagement.
This research confirm that job satisfaction mediate work environment to employee engagement although it is never consluce yet from prom previous research. Work environment and job satisfactin both positively and significaly impact employee engagement and these constructs may strengthen employee engagement, as well as work environment impact to strengthen job satisfaction
The Influence of Work Experience and Training on Internal Auditor Competence
Authors: Anggraeni Novita Dewi , Irawady Cahya 
Published: August 2023

Kompetensi adalah kemampuan dan karakteristik yang dimiliki oleh seseorang pemangku jabatan berupa pengetahuan, keahlian, sikap dan perilaku yang diperlukan dalam melaksanakan tugas serta jabatannya. Kompetensi terbagi menjadi dua bagian yaitu kompetensi umum dan kompetensi khusus. Kompetensi umum merupakan kemampuan serta karakteristik berupa pengetahuan dan perilaku. Untuk kompetensi umum dapat diperoleh dengan melalui pendidikan formal ataupun non dan pelatihan. Kompetensi khusus merupakan kemampuan serta karakteristik berupa keahlian yang diperlukan dalam melaksanakan tugas jabatannya. Penelitian ini bertujuan untuk menguji secara simultan maupun parsial apakah terdapat pengaruh pengalaman kerja ataupun pelatihan terhadap kompetensi yang dimiliki oleh auditor internal pada Inspektorat Jenderal Kementerian, Pendidikan, Kebudayaan, Riset dan Teknologi.
Pengaruh yang diuji dalam penelitian ini adalah pengalaman kerja yang dimiliki oleh masing-masing auditor dan pelatihan yang telah diikuti oleh auditor. Populasi yang digunakan dalam penelitian ini adalah seluruh auditor di Inspektorat Jenderal Kementerian Pendidikan, Kebudayaan, Riset dan Teknologi baik dari wilayah Inspektorat I, II, III, IV dan Investigasi. Teknik pengambilan sampel melalui teknik non probability sampling dengan metode purposive sampling. Untuk mengukur besaran sampel yang akan diteliti mengggunakan rumus slovin dengan menggunakan data primer yaitu melakukan penyebaran data menggunakan kuesioner kepada masing-masing auditor selaku responden. Metode yang digunakan dalam penelitian ini adalah metode kuantitatif melalui analisis statistik deskriptif dan metode regresi linear berganda.
Hasil penelitian ini menunjukkan bahwa kompetensi auditor internal secara signifikan dipengaruhi oleh pengalaman kerja dan pelatihan baik secara parsial maupun simultan.
CCS Potential in Louisiana
Authors: Bain Graham 
Published: August 2023

Abstract
The rapid evolution of the carbon sequestration landscape, driven by factors such as the Inflation Reduction Act and increased demand for carbon offsetting, necessitates an efficient method for identifying economically viable opportunities. Considering CO2 capture and storage, this study presents a workflow for assessing CCUS project viability. Focusing on southern Louisiana, we identified low-cost emitters through cost calculations and paired them with nearby storage sites. A geological model of tertiary sands was developed to determine reservoir storage volumes, injectivity, storage costs, and plume migration areas using the FE/NETL CO2 Saline Storage Cost Model. We generated a risk map considering factors such as wellbore penetrations, faults, earthquakes, caprock, freshwater aquifers, and salt domes to identify areas with higher chances of costly remediation or freshwater contamination.
Our findings reveal a significant cluster of emissions in southern Louisiana with a sub $50/tonne capture breakeven, accounting for over 80 million tonnes of CO2/year. Existing and potential pipelines can connect these emitters to storage sites with capacities ranging from 17.2 to 36.8 Mt CO2/section and storage beakevens between $8.50 and $14.50/tonne. Risk assessment indicates increased risk in the northern region due to the presence of freshwater aquifers and legacy wellbore penetrations. Comprehensive understanding of CO2 storage potential along the entire value chain is essential for project success, and our proposed workflow enables holistic screening of areas for new projects, helping secure pore space before competitors and facilitating deeper modeling in low-risk areas.
Analytic Solution for Partially Completed Horizontal Wells with Simulation Validation
Authors: Wilkinson David , Bailey William J. , Bajaj Aaditya , Vasper Adam 
Published: August 2023

Summary
This paper presents an inflow model for partially completed (PC) horizontal wells that is validated against a simulation benchmark with performance evaluated in terms of a normalized dimensionless productivity index (PI). The model is based on a pressure-averaged uniform flux line-source solution that builds upon the model proposed in 1991 by Goode and Wilkinson (GW) and is validated against a numerical simulation-based benchmark. The model is then subjected to a series of tests where specific inputs are allowed to diverge from the assumptions used to derive it, effectively a form of “stress test.” The rationale was to determine model accuracy when applied to wells that do not conform to the idealized well used to develop the model. Inputs “stress tested” include well inclination, asymmetric completion placement, anisotropy, and a significantly larger number of (shorter) completions, up to around 100 (compared to just three in the original GW model). In all cases, the model performed reasonably well, with divergence from the numerical benchmark quantified. However, for all tests, it was found that model accuracy was dependent on the open fraction, with accuracy increasing as the open fraction increased while model reliability became suspect when the open fraction was ≲ 0.3. Practical usage guidelines and limitations are presented along with associated input ranges and estimated divergence from benchmark. The model is thought suitable for inclined and/or undulating wells with a large number of completions—both long and short—with or without asymmetric placement in presence of anisotropy.
Genesis, Distribution, and Characterization of a Paleokarst Subsurface River System in the Tahe Area, Tarim Basin, Western China
Authors: Lyu Xinrui , Ju Binshan , Wu Xingwei , Xiao Fengying 
Published: August 2023

Summary
Subsurface river systems constitute one of three major paleokarst types that make up Ordovician reservoirs in the Tahe area of the Tarim Basin. The total length of the river system is approximately 400 km, and the reserves associated with this karst type are more than 200 million tons. However, it is manifested that 47% of drilled wells have not encountered river paleokarst, while 50% of wells that have encountered river paleokarst are fully filled due to the poor understanding of the paleokarst of this region, resulting in a significant variation of production capacities. In this study, we propose a detailed data integration approach with outcrops, drilling, logging, seismic profiles, and dynamic data to delineate the complex paleokarst river system in the Tahe area. The karst geological theory with reservoir characterization is combined in particular. The workflow of clarifying the main controlling factors, architecture types, and development distribution modes of the subsurface river system is established. Fill material type, sequence of fill structure, and fill controlling factors are also revealed. A quantitative characterization method of the subsurface rivers is established adopting predictions based on seismic data and high-resolution geostatistical and geological modeling. The Ordovician reservoirs in the Tahe area comprise three paleokarst river systems with different characteristics. Karst paleogeomorphology is the main control over the overall flow direction and plane distribution of the subsurface rivers. Changes in the surface of the phreatic zone are crucial in controlling the vertical layers and scale of the rivers. The combined action of faults plays a decisive role in controlling the anastomosing pattern of the rivers. Single-branch channels, reticulated channels, and structural corridors in single-layer or multilayer styles are the main subsurface river types. Trunk channels, branch channels, hall caves, and inlets/outlets are dominant structures in the architecture of the river system. Sand-mud, breccia, and chemically precipitated materials are the most common fill types. Three typical sequences of fill structure and four spatial combination modes exist in the subsurface river system. The morphology and fill characteristics of rivers are predictable using seismic attributes, such as frequency division energy, frequency division inversion, and coherent energy gradient. 3D models are constructed by multivariate control multipoint geostatistical method, which can characterize the strong heterogeneity characteristics of subsurface river systems. This complex paleokarst system enables remarkable results for the adjustment of the reservoir development plan through quantitative characterization.
Mudan Granules for Diabetic Peripheral Neuropathy: A Systematic Review of Preclinical and Clinical Evidence
Authors: Zhou Jianlong , Zhu Lv , Li Yadi 
Published: August 2023

Abstract
Background
Mudan granules has been used in China to treat diabetic peripheral neuropathy (DPN), but there is a lack of systematic review of reports in this area. The aim of this systematic review was to evaluate the efficacy and safety of Mudan granules in the treatment of diabetic peripheral neuropathy.
Methods
Initial studies were searched from PubMed, Embase, Cochrane, China National Knowledge Infrastructure (CNKI), VIP database, Wanfang electronic databases. The Cochrane Risk of Bias tool was used to evaluate the risk of bias. The meta-analysis was performed by Stata 16.0 software. For dichotomous and continuous outcomes, the relative risk (RR) and standardized mean difference (SMD) with 95% confidence interval (CI) were conducted, respectively.
Results
51 randomized controlled trials (RCTs) involving 5,416 patients were included. In the meta-analysis, compared with routine treatment (RT) alone, Mudan granules plus RT reduced Toronto clinical scoring system (TCSS) score (SMD, -0.52; 95% CI, -0.66 to -0.38; P < 0.01), total symptoms score (TSS) (SMD, -1.44; 95% CI, -2.88 to -0.00; P = 0.05), serum homocysteine (Hcy) levels (SMD, -3.84; 95% CI, -5.99 to -1.70; P < 0.01), serum high sensitive C-reactive protein (hs-CRP) levels (SMD, -1.68; 95% CI, -3.29 to -0.08; P = 0.04), and improved total clinical efficacy (RR, 1.23; 95% CI, 1.19 to 1.27; P < 0.01) and serum superoxide dismutase (SOD) levels (SMD, 1.54; 95% CI, 1.13 to 1.95; P < 0.01). Besides, Mudan granules presented an adjuvant efficacy on median motor nerve conduction velocity (SMD, 1.61; 95% CI, 1.16 to 2.07), median sensory nerve conduction velocity (SMD, 1.73; 95% CI, 1.26 to 2.20), common peroneal motor nerve conduction velocity (SMD, 1.48; 95% CI, 1.10 to 1.86), common peroneal sensory nerve conduction velocity ( SMD, 1.57; 95% CI, 1.23 to 1.92), tibial motor nerve conduction velocity (SMD, 1.34; 95% CI, 0.82 to 1.87), and tibial sensory nerve conduction velocity (SMD, 1.03; 95% CI, 0.86 to 1.20). In terms of adverse events, there was no statistically significant difference between the trial group and the control group (P=0.87). Five preclinical studies were also retrieved for the study. Animal studies have shown that Mudan granules have anti-oxidative stress effects and could reduce the inflammatory response. It may improve peripheral nerve injury in diabetic rats by modulating the TLR4/MyD88/NF-κB pathway, TLR4/p38 MAPK pathway and PI3K/AKT pathway.
Conclusions
Mudan granules presented an adjuvant efficacy on patients with DPN and could improve the oxidative stress and inflammatory levels in preclinical models. However, high-quality original studies are needed to further prove the evidence.
Systematic review registration: PEROPERO (CRD42022373113)
Determination of acousto-ultrasonic wave propagation in an isotropic aluminium Al6082-T6 plate
Authors: PRASAD KUMAR SHANTANU , Jombo Gbanaibolou , Ismail Sikiru Oluwarotimi , Chen Yong Kang , Dhakal Hom Nath 
Published: August 2023

Abstract
The ability to guarantee reliable and damage-tolerant operation of structures is critical to their safe operation. Various non-destructive evaluation (NDE) techniques, such as ultrasonics, acoustic emission, thermography, acousto-ultrasonics (AU), among others could potentially provide a means of inspecting cracks, defects and damage responses in structures. The main aim of this study is to look into the physical problem of AU wave propagation through an isotropic plate and its analytical validation, using wave dispersion concept. The experimental investigation was conducted on aluminium Al6082-T6 alloy plate specimen. Wave propagation speed on top and bottom surfaces of the plate was investigated. The variation of the wave speed and attenuation with frequency were identified. From the results obtained experimentally, the wave dispersion was verified analytically. Interestingly, Lamb waves were discovered to be the dominating AU waves. The wave was appreciably non-dispersive in the frequency extent from 150 kHz to 1 MHz and the attenuation coefficient was increased with the frequency. This finding provides a significant breakthrough to the implementation of acousto- ultrasonics in the non- destructive testing applications, such as accessing the damage in composite structures, including wind turbine blades. AU has an active sensing mechanism, providing an edge over acoustic emission (AE) method which is a passive mode of damage sensing and detection, as external loading is needed for the damage sensing.