bluuebunny/crossref_metadata_2025_split huggingface dataset:
Types of co-occurring patterns of mental health among the disaster victims in South Korea
Authors: Lee Kyeong-Won , Lee Hyun 
Published: February 2023

AbstractThis study examined co-occurring patterns of mental health among disaster victims using latent profile analysis and assessed the difference between sociodemographic factors and protective factors that affect group classification. The data of 2300 disaster victims from 2019 (4th wave) NDMI (National Disaster Management Research Institute) for Long-term Survey on the Change of Life of Disaster Victims were analyzed. The latent profile analysis revealed that three profiles; High comorbid symptom (HCS) (6.2%), Medium comorbid symptom (MCS) (22.6%), and Low symptom (LS) (71.2%). The factors that explain the difference in this divided profile group were the type of disaster, hurt, income, age, elapsed years, resilience, and community resilience in the multinomial logistic regression. When individual resilience and community resilience are high, more effective in making people belong to the low comorbid symptom group. Therefore, there is a need for a strategy that promotes synergy between the two relationships while maintaining a dual focus point of view that fosters resilience at the individual and community level together.
Longitudinal association between executive function and academic achievement in children with neurofibromatosis type 1 and plexiform neurofibromas
Authors: Hou Yang , Wu Xian , Allen Taryn , Toledo-Tamula Mary Anne , Martin Staci , Gillespie Andy , Goodwin Anne , Widemann Brigitte C. , Wolters Pamela L. 
Published: February 2023

AbstractObjective:To examine how executive functioning (EF) relates to academic achievement longitudinally in children with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PNs) and whether age at baseline moderates this relationship.Method:Participants included 88 children with NF1 and PNs (ages 6–18 years old, M = 12.05, SD = 3.62, 50 males) enrolled in a natural history study. Neuropsychological assessments were administered three times over 6 years. EF (working memory, inhibitory control, cognitive flexibility, and attention) was assessed by performance-based (PB) and parent-reported (PR) measures. Multilevel growth modeling was used to examine how EF at baseline related to initial levels and changes in broad math, reading, and writing across time, controlling for demographic variables.Results:The relationship between EF and academic achievement varied across EF and academic domains. Cognitive flexibility (PB) uniquely explained more variances in initial math, reading, and writing scores; working memory (PB) uniquely explained more variances in initial levels of reading and writing. The associations between EF and academic achievement tended to remain consistent across age groups with one exception: Lower initial levels of inhibitory control (PR) were related to a greater decline in reading scores. This pattern was more evident among younger (versus older) children.Conclusions:Findings emphasize the heterogeneous nature of academic development in NF1 and that EF skills could help explain the within-group variability in this population. Routine cognitive/academic monitoring via comprehensive assessments and early targeted treatments consisting of medication and/or systematic cognitive interventions are important to evaluate for improving academic performance in children with NF1 and PNs.
A note on international spillovers of economic policy uncertainty across business cycles: evidence from OECD countries
Authors: Popp Aaron , Zhang Fang 
Published: February 2023

AbstractWe estimate a smooth-transition vector autoregression model (ST-VAR) using panel data from 14 OECD countries to study the cross-country spillover effects of economic policy uncertainty (EPU) shocks. An unexpected elevation of EPU originating abroad has an overall contractionary real effect, and the spillover effects depend on the state of the business cycle of the recipient country. EPU spillover shocks during recessions have stronger but less persistent effects on a number of economic indicators. We also find that the interconnectedness of EPU, financial markets, and business confidence are important channels for the EPU shocks to propagate across countries, while the trade channel has limited effects, especially during expansions.
Credit market developments and sectoral business cycles worldwide
Authors: Ulussever Talat , Kilinc Mustafa 
Published: February 2023

AbstractThis paper investigates the relationship between credits and sector-level output dynamics in a sample of 41 advanced and developing countries. The existing literature shows that household credits are associated with boom-bust cycles in aggregate output, whereas business loans do not cause such output dynamics. The present paper expands these findings in terms of advanced versus developing countries and manufacturing versus services sectors. The new findings indicate that the resulting boom-bust cycles in the aggregate output in response to household credits are generally observed in the sample of developing countries, with no similar dynamics in the advanced countries. Another significant conclusion is that the boom-bust cycles are generated mostly in the services sector. No equivalent boom-bust dynamics are observed in the manufacturing sector, but the negative medium-run effects of household credits are larger in this sector. These findings indicate that credit mechanisms and consequences can significantly vary across countries and sectors.
Lost Arias from Ifigenia in Tauri (1713) in Thomas Gray's Music Collection: ‘E posto in Musica dal Sig. Domenico Scarlatti’?
Authors: Dupuis-Désormeaux Nathalie 
Published: February 2023

AbstractThis article shares the exciting discovery of previously unidentified arias within the music amassed by the eighteenth-century English poet Thomas Gray. His ten-volume collection, now held at the Lewis Walpole Library, Yale University, contains some of the only surviving copies of important arias dating back as far as 1690 and bears many annotations by Gray listing performance venues, composers, opera roles and singers. One volume of the collection contains many unattributed works, among which I identify a number of arias. Five of them match the libretto to La caduta del regno dell'Amazzoni (1690) and another corresponds to Il Colombo overo l'India scoperta (1691), both operas originally set by Bernardo Pasquini. The texts of the two ensuing arias align with Carlo Sigismondo Capeci's libretto for Ifigenia in Tauri (1713), the opera he wrote with Domenico Scarlatti for their patroness, Maria Kazimiera Sobieska. In addition, in the first pages of the assemblage, instructions in Gray's hand on how to execute a basso-continuo accompaniment continue from another volume, where he entitled these ‘Regole per l'Accompagnamento’ and interwove them with a ‘Toccata per il Cembalo’. This article seeks to describe the newfound works and stimulate study into the full contents of Gray's music collection, but its main focus is on the two excerpts from Ifigenia in Tauri and their possible attribution to Domenico Scarlatti. Salient characteristics of these scores are presented, as is an evaluation of their concordance with Capeci's libretto. Further, I underline features that these numbers share with other Ifigenia in Tauri arias known to be by Domenico Scarlatti and provide comprehensive tables detailing equivalent structural proportions.
‘Theatre as a Nursery of Language’: Learning French through Vaudeville Tunes in Eighteenth-Century England
Authors: Levenson Erica P. 
Published: February 2023

AbstractThis article examines how French vaudeville tunes circulated in England through both theatrical performances and French-language textbooks (or ‘grammars’). My central concern is to consider how audiences in London – who had little exposure to the rich satirical and cultural connotations that these tunes had acquired over years of performance in Paris – might have been able to grasp their significance within staged works performed by visiting Parisian troupes between the years 1718 and 1735. I suggest that in tracing the transmission of tunes from France to England, scholars should consider a wider range of print sources, since vaudevilles had a social life extending beyond the plays in which they were performed. To this end, I focus on analysing vaudevilles found in French ‘grammars’. The pedagogical nature of these sources explicitly puts on display how French culture was translated for an English readership. By comparing the tunes found in grammars with plays that used the same tunes, I reveal both how Londoners could have become acquainted with the Parisian understanding of French tunes and how the grammar books could have shifted the meanings of these tunes for English readers and audiences. Ultimately, the circulation of French tunes abroad through grammars directs our attention to the material and cultural practices undergirding the mobility of eighteenth-century musical culture.
Regolith of the Crater Floor Units, Jezero Crater, Mars: Textures, Composition, and Implications for Provenance
Authors: Vaughan Alicia , Minitti Michelle E. , Cardarelli Emily L. , Johnson Jeffrey R. , Kah Linda C. , Pilleri Paolo , Rice Melissa S. , Sephton Mark , Horgan Briony H. N. , Wiens Roger C. , Yingst R. Aileen , Zorzano Mier Maria‐Paz , Anderson Ryan , Bell James F. , Brown Adrian J. , Cloutis Edward A. , Cousin Agnes , Herkenhoff Kenneth E. , Hausrath Elisabeth M. , Hayes Alexander G. , Kinch Kjartan , Merusi Marco , Million Chase C. , Sullivan Robert , Siljeström Sandra M. , St. Clair Michael 
Published: February 2023

AbstractA multi‐instrument study of the regolith of Jezero crater floor units by the Perseverance rover has identified three types of regolith: fine‐grained, coarse‐grained, and mixed‐type. Mastcam‐Z, Wide Angle Topographic Sensor for Operations and eNgineering, and SuperCam Remote Micro Imager were used to characterize the regolith texture, particle size, and roundedness where possible. Mastcam‐Z multispectral and SuperCam laser‐induced breakdown spectroscopy data were used to constrain the composition of the regolith types. Fine‐grained regolith is found surrounding bedrock and boulders, comprising bedforms, and accumulating on top of rocks in erosional depressions. Spectral and chemical data show it is compositionally consistent with pyroxene and a ferric‐oxide phase. Coarse‐grained regolith consists of 1–2 mm well‐sorted gray grains that are found concentrated around the base of boulders and bedrock, and armoring bedforms. Its chemistry and spectra indicate it is olivine‐bearing, and its spatial distribution and roundedness indicate it has been transported, likely by saltation‐induced creep. Coarse grains share similarities with the olivine grains observed in the Séítah formation bedrock, making that unit a possible source for these grains. Mixed‐type regolith contains fine‐ and coarse‐grained regolith components and larger rock fragments. The rock fragments are texturally and spectrally similar to bedrock within the Máaz and Séítah formations, indicating origins by erosion from those units, although they could also be a lag deposit from erosion of an overlying unit. The fine‐ and coarse‐grained types are compared to their counterparts at other landing sites to inform global, regional, and local inputs to regolith formation within Jezero crater. The regolith characterization presented here informs the regolith sampling efforts underway by Perseverance.
Pediatric sepsis diagnostic and prognostic biomarkers: pancreatic stone protein, copeptin, and apolipoprotein A-V
Authors: Saleh Nagwan Y. , Aboelghar Hesham M. , Garib Mohamed I. , Rizk Mohammed S. , Mahmoud Asmaa A. 
Published: February 2023

Abstract
Background
We assessed serum concentrations of pancreatic stone protein (PSP), copeptin, and apolipoprotein A-V (APOA5) biomarkers for the diagnosis and prognosis of pediatric sepsis, a condition associated with high mortality.

Methods
This prospective study included 180 children admitted to the Pediatric Intensive Care Unit and 100 healthy controls at Menoufia University Hospital. Pediatric Risk of Mortality (PRISM), Pediatric Index of Mortality-2 (PIM2), and Pediatric Sequential Organ Failure Assessment (pSOFA) scores were calculated. Serum PSP, copeptin and APOA5 were measured once within 24 h of admission.

Results
PSP, copeptin, and APOA5 were significantly higher in the patients than in the controls (p < 0.001). PSP and copeptin were increased among children who required mechanical ventilation (MV), had multiple organ dysfunctions, and were non-survivors, but APOA5 was decreased in those children. Logistic regression analyses showed that high pSOFA, high PSP and copeptin, low APOA5, and use of MV were associated with mortality. The receiver operating characteristic revealed that the area under the curve (AUC) for APOA5, copeptin, and PSP (0.965, 0.960, and 0.868, respectively) demonstrated high sensitivity (96%, 94%, and 80%) for sepsis diagnosis. The AUC values for PSP, copeptin, and APOA5 were 0.709, 0.705, and 0.571, respectively, with sensitivities of 74%, 58%, and 58% for mortality prediction.

Conclusions
PSP, copeptin, and APOA5 are promising diagnostic biomarkers for pediatric sepsis but inadequate predictors of mortality.

Impact

Apolipoprotein A-V (APOA5), copeptin, and pancreatic stone protein (PSP) are acute-phase proteins with diagnostic value in evaluating critically ill pediatric patients with sepsis and detecting sepsis severity.

PSP and copeptin had the power to discriminate non-survivors from survivors.

APOA5 was less powerful than the other biomarkers in discriminating between survivors and non-survivors.
Deep brain stimulation of the nucleus accumbens in treatment-resistant alcohol use disorder: a double-blind randomized controlled multi-center trial
Authors: Bach Patrick , Luderer Mathias , Müller Ulf Joachim , Jakobs Martin , Baldermann Juan Carlos , Voges Jürgen , Kiening Karl , Lux Anke , Visser-Vandewalle Veerle ,   the DeBraSTRA study group, Klosterkötter Joachim , Huys Daniel , Sommer Wolfgang , Weber Tillmann , Bogerts Bernhard , Kuhn Jens , Mann Karl 
Published: February 2023

AbstractTreatment resistance in alcohol use disorders (AUD) is a major problem for affected individuals and for society. In the search of new treatment options, few case studies using deep brain stimulation (DBS) of the nucleus accumbens have indicated positive effects in AUD. Here we report a double-blind randomized controlled trial comparing active DBS (“DBS-EARLY ON”) against sham stimulation (“DBS-LATE ON”) over 6 months in n = 12 AUD inpatients. This 6-month blind phase was followed by a 12-month unblinded period in which all patients received active DBS. Continuous abstinence (primary outcome), alcohol use, alcohol craving, depressiveness, anxiety, anhedonia and quality of life served as outcome parameters. The primary intention-to-treat analysis, comparing continuous abstinence between treatment groups, did not yield statistically significant results, most likely due to the restricted number of participants. In light of the resulting limited statistical power, there is the question of whether DBS effects on secondary outcomes can nonetheless be interpreted as indicative of an therapeutic effect. Analyses of secondary outcomes provide evidence for this, demonstrating a significantly higher proportion of abstinent days, lower alcohol craving and anhedonia in the DBS-EARLY ON group 6 months after randomization. Exploratory responder analyses indicated that patients with high baseline alcohol craving, depressiveness and anhedonia responded to DBS. The results of this first randomized controlled trial are suggestive of beneficial effects of DBS in treatment-resistant AUD and encourage a replication in larger samples.
Identification of a tomato UDP-arabinosyltransferase for airborne volatile reception
Authors: Sugimoto Koichi , Ono Eiichiro , Inaba Tamaki , Tsukahara Takehiko , Matsui Kenji , Horikawa Manabu , Toyonaga Hiromi , Fujikawa Kohki , Osawa Tsukiho , Homma Shunichi , Kiriiwa Yoshikazu , Ohmura Ippei , Miyagawa Atsushi , Yamamura Hatsuo , Fujii Mikio , Ozawa Rika , Watanabe Bunta , Miura Kenji , Ezura Hiroshi , Ohnishi Toshiyuki , Takabayashi Junji 
Published: February 2023

AbstractVolatiles from herbivore-infested plants function as a chemical warning of future herbivory for neighboring plants. (Z)-3-Hexenol emitted from tomato plants infested by common cutworms is taken up by uninfested plants and converted to (Z)-3-hexenyl β-vicianoside (HexVic). Here we show that a wild tomato species (Solanum pennellii) shows limited HexVic accumulation compared to a domesticated tomato species (Solanum lycopersicum) after (Z)-3-hexenol exposure. Common cutworms grow better on an introgression line containing anS. pennelliichromosome 11 segment that impairs HexVic accumulation, suggesting that (Z)-3-hexenol diglycosylation is involved in the defense of tomato against herbivory. We finally reveal that HexVic accumulation is genetically associated with a uridine diphosphate-glycosyltransferase (UGT) gene cluster that harborsUGT91R1on chromosome 11. Biochemical and transgenic analyses of UGT91R1 show that it preferentially catalyzes (Z)-3-hexenyl β-d-glucopyranoside arabinosylation to produce HexVicin planta.
The accuracy and usability of point-of-use fluoride biosensors in rural Kenya
Authors: Thavarajah Walter , Owuor Patrick Mbullo , Awuor Diana Ross , Kiprotich Karlmax , Aggarwal Rahul , Lucks Julius B. , Young Sera L. 
Published: February 2023

AbstractGeogenic fluoride contaminates the water of tens of millions of people. However, many are unaware of the fluoride content due in part to shortcomings of detection methods. Biosensor tests are a relatively new approach to water quality testing that address many of these shortcomings but have never been tested by non-experts in a “real-world” setting. We therefore sought to assess the accuracy and usability of a point-of-use fluoride biosensor using surveys and field tests in Nakuru County, Kenya. Biosensor tests accurately classified elevated fluoride (≥1.5 ppm) in 89.5% of the 57 samples tested. Usability was also high; all participants were able to use the test and correctly interpreted all but one sample. These data suggest that biosensor tests can provide accurate, meaningful water quality data that help non-experts make decisions about the water they consume. Further scaling of these technologies could provide new approaches to track global progress towards Sustainable Development Goal 6.
The profiles of miR-4510 expression level in breast cancer
Authors: Majed Sevan Omer , Mustafa Suhad Asad 
Published: February 2023

AbstractMicroRNA that is abnormally produced in breast cells can disrupt biological processes, which can lead to cancer. This study aims to screen differentially expressed genes (DEGs) and ncRNAs (DEncRNAs) in the formalin-fixed paraffin-embedded (FFPE) tissues of breast cancer (BC) as compared with the normal adjacent tissues (NAT), and identify miR-4510 as a novel biomarker of BC. This study looked at differentially expressed genes (DEGs) using MACE-Seq and differentially expressed ncRNAs (DEncRNAs) using the small RNA-Seq. Real-time qPCR was used to determine the level of expression of miR-4510. In this study, MACE-Seq results showed that 26,795 genes, with a p-value < 0.05, were differentially expressed in BC paraffin tissues as compared with NAT. Small RNA-Seq results revealed that 1326 ncRNAs, with a p-value < 0.05, were differentially expressed. We confirmed that miR-4510 was significantly down-expressed (p-value = 0.001) by qRT-PCR in the paraffin tissue of 120 BC patients. Based on eleven computational prediction programs, TP53, TP53INP1, MMP11, and COL1A1 for the miR-4510 were identified as miR-4510 targets. The MACE-seq result showed that the gene of TP53 (p-value = 0.001) and TP53INP1 (p-value = 0.02) was significantly down-regulated, but the gene of MMP11 (p-value = 0.004) and COL1A1 (p-value = 0.0001) was significantly over-expressed in 20 paired specimens of the BC and NAT. We discovered that a single SNP inside the miR-4510 binding site occurred only in BC, in which Guanine (G) changed into Adenine (A). Two SNPs outside the miR-4510 binding site occurred, and Guanine (G) in both BC and NAT was changed into Thymine (T), as compared to the reference sequence (RefSeq). Overall, our results suggested that miR-4510 functions as a tumor suppressor in the BC. Mir-4510 may act as a tumor suppressor, however additional experimental data is needed to corroborate these assumptions and can be exploited as a biomarker for BC.
Dynamic characteristics of skin reaction force in different body postures
Authors: Marsidi Nick , Scheepens Karlijn M. J. , Goeman Jelle J. , Horeman Tim , Genders Roel E. 
Published: February 2023

AbstractMechanical stress influences scarring of a surgical wound. Several lines have been proposed for the best excision direction. It is unknown if these lines still apply when the body posture changes. The objective is to measure the skin reaction force in four directions and determine the direction of least force. Secondary objective is to determine if the reaction force varies in a different body posture. Skin reaction force was measured with the compressiometer in 30 participants on four different locations (forearm/upper arm/shoulder blade/lower back) in four directions (0°–45°–90°–135°) and two body postures. The direction of least skin reaction force changed with a different body posture and was significant for the forearm (p < 0.01) and shoulder blade (p = 0.05) The skin reaction force in all four direction changed significantly in a different body posture, except the 45° line in the upper arm and shoulder blade. Our results demonstrate that the skin reaction force in four directions in four locations varies with change in body posture. Focus should therefore not only lay on choosing the right direction, but also on managing skin tension postoperatively.
Optimisation of the techno-functional and thermal properties of heat moisture treated Bambara groundnut starch using response surface methodology
Authors: Mathobo Vhulenda Melinda , Onipe Oluwatoyin Oladayo , Silungwe Henry , Ramashia Shonisani Eugenia , Anyasi Tonna Ashim 
Published: February 2023

AbstractThis work optimised the techno-functional and thermal properties of heat moisture treated Bambara groundnut starch (BGS). A central composite rotatable design (Design-Expert software v8.0.1.0) comprising two independent factors of temperature and time was used. Extracted BGS were subjected to heat-moisture treatment (HMT) at 80–120 °C for 30–90 min at different moisture levels of 15% (HMT 15-BGS), 25% (HMT 25-BGS) and 35% (HMT 35-BGS). The optimum HMT conditions for BGS were found to be 80 °C for 30 min (HMT 15), 105.74 °C for 30 min (HMT 25), and 113.16 °C for 30 min (HMT 35). The desirability values of the obtained optimum conditions were 0.63 (HMT 15) and 1.00 (HMT 25 and 35). In HMT 35-BGS, water absorption capacity was significantly affected by the quadratic effect of temperature and time. In contrast, solubility was significantly affected by the linear effect of time and the quadratic effect of temperature. Temperature and treatment time had no significant effect (p ≥ 0.05) on the differential scanning calorimetry thermal properties of HMT 15, 25 and 35-BGS. Scanning electron micrographs of optimised BGS showed round and oval-shaped starch granules ranging from 4.2 to 4.7 mm (width) and 10 μm for length. Unmodified and optimised HMT–BGS showed characteristic FTIR bands linked with common starches. All BGS samples displayed multiple vibrations in the region below 1000 cm−1 due to the skeletal vibrations of the glucose pyranose ring.