bluuebunny/crossref_metadata_2025_split huggingface dataset:
A scoping review protocol to identify strategies to implement evidence-based diabetic foot disease guidelines for healthcare professionals in primary care
Authors: Naughten Enda , Giltenane Martina , O'Brien Tim , Ivory John , Gethin Georgina 
Published: March 2023

Background: Diabetes mellitus has been identified as a serious global public health concern. Diabetic foot disease is one of four major complications that impacts on people with the disease and health systems. The majority of diabetic foot care, including screening and treatment, occurs in the primary care sector. To provide optimal care, evidence-based guidance is essential for all healthcare professionals. There is little known about the implementation of these guidelines in primary care settings. The aim of this scoping review will be to identify strategic components used to support the implementation of diabetic foot disease evidence-based practice guidelines by healthcare professionals in primary care. Methods: A scoping review drawing on methods and guidance from the Joanna Briggs Institute will be conducted and will be reported according to the PRISMA-ScR Checklist. This study will retrieve literature on strategic components used to implement diabetic foot disease evidence-based practice guidelines by health professionals in primary care, through a comprehensive search strategy in the following databases: CINAHL; Medline (Ovid); Embase; the Cochrane Library; and PsycINFO. Grey literature will be searched within the references of identified articles and in Lenus, BASE and LILACS. A data charting form will be developed with categories including: article details, population demographics, implementation strategies, strategy details, and evaluation methods such as feasibility and effectiveness, duration of intervention and duration of follow up. Conclusions: Promoting foot care for people with diabetes in the primary care setting can make a significant impact on overall outcomes for the person and the health service. However, without the transition of evidence-based guidelines to practice, the impact can be difficult to assess. This study will map the evidence that can assist the transfer of evidence-based practice guidelines for diabetic foot care to healthcare professionals in primary care.
Irritable bowel syndrome – modern ways of treatment
Authors: Kuciński Jakub , Fryska Zuzanna , Wołejko Adam , Kulik Kacper , Semeniuk Paweł , Matusz Krystian , Burczyk Rafał , Górna Natalie 
Published: March 2023

Introduction
Irritable bowel syndrome (IBS) is the most frequent functional disorder of the gastrointestinal tract. Main symptoms are recurring stomach ache connected with defecation, changes of frequency of defecation and/or stool’s consistency. Cause of IBS is still unknown unlike its pathomechanism. Continuous research allows doctors to understand and treat it better.
Discussion
Diagnosing IBS might be difficult even for the most experienced doctors due to its uncharacteristic symptoms. Therefore diagnosis should be made by using Rome IV Criteria. IBS is divided into 4 subtypes basing on clinical picture: IBS with predominant constipation, IBS with predominant diarrhea, IBS with mixed bowel habits and IBS unclassified. Classification is being performed with the use of Bristol Stool Chart. Choice of remedy should be made depending on the subtype of IBS. Pharmacological treatment is symptomatic and focuses on relieving pain, diarrhea, constipation and bloating. Drugs that can be used are: loperamide, rifaximin, antispasmodic (e.g. hyoscine), antidepressants or laxatives. Treatment should also contain nonpharmacological methods. Nonpharmacological techniques which are proved to help patients contain regular physical activity, body mass reduction, low-FODMAP diet, using probiotics, psychotherapy and supplementing soluble fibre.
Conclusions
IBS is a big issue for public health as it is lowering quality of life and is generating big indirect costs. Difficulties in diagnosing are increasing those costs. That’s why it is of high importance to find more effective therapy. Raising awareness among doctors is crucial as plenty of methods are available to treat the disease which allows to reduce symptoms and costs.
Unlocking the Inventive Potential of Knowledge Distance in Teams: How Intrateam Network Configurations Provide a Key
Authors: Vestal Alex , Danneels Erwin 
Published: March 2023

Increasingly, teams consist of members from widely distinct knowledge domains. This article studies the extent to which research and development (R&D) teams can transform their members’ different technological knowledge into impactful inventions. Although teams composed of members with distinct expertise can create impactful new technologies, in order to realize this potential, team members must have the ability and motivation to integrate each other’s knowledge. This article argues that the ability to do so is shaped by the patterns of intrateam ties, measured in terms of coauthorships on patents. Our results suggest that teams’ ability to reap the advantages of members’ distinct expertise is shaped by the patterns of members’ prior collaboration ties. Prior experience working together (i.e., density) and the presence of factions of team members with common history (i.e., subgroups) improve teams’ ability to leverage differences in members’ knowledge. In contrast, when prior collaborations center on one focal person (i.e., centralization), teams are less able to take advantage of the knowledge differences on the team. An analysis of 32,612 nanotechnology R&D teams provides support for the hypotheses.Supplemental Material: The online appendix is available at https://doi.org/10.1287/orsc.2023.1665 .
Transportation Asset Acquisition under a Newsvendor Model with Cutting-Stock Restrictions: Approximation and Decomposition Algorithms
Authors: Wagenaar Joris , Fragkos Ioannis , Faro W. L. C. 
Published: March 2023

Logistics service providers use transportation assets to offer services to their customers. To cope with demand variability, they may acquire additional assets on a one-off (spot) basis. The planner’s problem is to determine the optimal level of assets acquired upfront, such that their cost is minimized, for a given planning horizon. Our formulation captures a nontrivial complication: Although ordering quantities are pertinent to asset acquisition, customer demand is in the form of service requests. Not only does each request have a stochastic duration, but also the total number of requests per customer is uncertain. We introduce a two-stage newsvendor model where demand for spot assets is derived through optimal cutting-stock patterns. Leveraging results from bin-packing, we propose polynomial algorithms that have worst-case guarantees for upper and lower bounds. Our method finds optimal solutions to instances intractable by commercial solvers. We investigate demand variability by means of a factorial experiment. We find that, whereas variability in the number of requests leads to higher costs, variability in each request’s duration can reduce costs. Finally, we demonstrate the modularity of our approach with two extensions: asset routing and outsourcing. Our results provide a practical approach to transportation asset acquisition and offer insights on the differing impact of demand uncertainty on the total acquisition cost. Supplemental Material: The online appendix is available at https://doi.org/10.1287/trsc.2023.1201 .
Altitude pre-acclimatization with an erythropoiesis-stimulating agent
Authors: Heldeweg Micah Liam Arthur , Medina Feliz Jonathan Xavier , Berend Kenrick 
Published: March 2023

Introduction: High altitude illness is a complication of rapid ascent above 2,500 m elevation. Ventilatory, circulatory and haematological adjustments, known as acclimatization, occur to maintain adequate delivery of oxygen. Although (non-)pharmaceutical strategies that modulate ventilation and circulation have long been accepted, the haematological approach has not. Case description: This report describes the application of a comprehensive strategy, including prior pre-acclimatization using an erythropoiesis-stimulating agent (ESA), in two healthy subjects ascending from sea level to 6,268 m. Following ESA administration 30 days prior to ascent, the subjects had a cumulative haemoglobin rise of 7.1% and 11.9%, respectively. Both subjects experienced minimal symptoms during four incremental ascents to the final altitude and no adverse events occurred. Discussion: This report has limited external validity, lacking both a sample size and controls, but can serve as practical exploration of the concept. Administration of an ESA may be a safe and useful pre-acclimatization strategy but cannot be recommended based on current evidence. More comprehensive research is needed.
Spectral power profile optimization of a field-deployed wavelength-division multiplexing network enabled by remote EDFA modeling
Authors: Jones Rasmus T. , Bottrill Kyle R. H. , Taengnoi Natsupa , Petropoulos Periklis , Yankov Metodi P. 
Published: March 2023

We propose a technique for modeling erbium-doped fiber amplifiers (EDFAs) in optical fiber networks, where the amplifier unit is located at a distant node outside the laboratory. We collect data on an optical point-to-point link with the amplifier as the only amplification stage. Different amplifier operating points are modeled using probe signals and by adjusting the settings of the amplifier through a control network. The data are used to train a machine learning algorithm integrated within a physical EDFA model. The obtained mathematical model for the amplifier is used to model all amplifiers of a network and links with multiple amplification stages. To confirm the modeling accuracy, we thereafter predict and optimize launch power profiles of two selected links in the network of 439.4 km and 592.4 km lengths. Maximum/average channel optical signal-to-noise ratio prediction errors of 1.41/0.68 dB and 1.62/0.83 dB are achieved for the two multi-span systems, respectively, using the EDFA model trained on the single span system with margin-optimized launch power profiles. Up to 2.2 dB of margin improvements are obtained with respect to unoptimized transmission.
Analytical investigation of GeO2-doped optical fibers to build Brillouin lasers at 1300  nm
Authors: Silva Luís C. B. , Segatto Marcelo E. V. 
Published: March 2023

The 1.5 µm spectral region concentrates the most substantial attention on building fiber laser sources for communications applications. However, data transmission in this spectral region is quite congested, requiring exploring new neighboring regions. In particular, 1.3 µm, usually defined as the zero-dispersion band, currently constitutes an active field of research, and the development of fiber laser sources in this wavelength band is of substantial interest to expand the capabilities of existing photonic operations. Previous experimental investigations have already shown that the peak stimulated Brillouin scattering efficiency is strongly affected by the concentration of GeO2 doping in single-mode fibers. In this context, this work presents an analytical investigation of the performance of a Brillouin fiber laser at 1.3 µm using optical fibers doped with different GeO2 concentrations as a Brillouin gain medium. The results obtained suggest that optical fibers doped with high GeO2 concentrations can be a simple and effective solution to build Brillouin lasers with better efficiency in the 1.3 µm band employing shorter fiber lengths with low pump power values.
O estigma da infertilidade e as “pressões sociais” que conduzem à reprodução assistida no oeste paranaense
Authors: Heidemann Samuelli Cristine Fernandes , Volpato Elaine Cristina Francisco 
Published: March 2023

O artigo reflete sobre como a vida das mulheres é socialmente condicionada para o ideal cultural da maternidade, de modo que muitas das que não se encaixam na condição de mães-esposas, impossibilitadas devido a questões biológicas, recorrem a tratamentos reprodutivos tecnológicos.
PALAVRAS-CHAVE: Mulheres. Maternidade. Tecnologias Reprodutivas. Imperativo Social.
Mulheres na Política
Authors: Colnago Gabriela Fernandes , Cirne Mariana Barbosa 
Published: March 2023

52% dos eleitores são mulheres, mas elas representam apenas 15,3% do Congresso Nacional. A pesquisa analisou 73 projetos de lei federais, de 1997-2021, sobre a representação feminina na política para identificar quem os propõem e, se buscam uma equidade da representação e quais os partidos.
PALAVRAS-CHAVE: Representação Política. Legislativo federal. Mulheres.
Analysis on the Characteristics of Asphalt Concrete Mixture Utilizing Reclaimed Asphalt Pavement with Waste Cooking Oil Rejuvinator
Authors: Thanaya, ME., PhD I Nyoman Arya , Ariawan I Made Agus , Wibawa I Putu Chandra 
Published: March 2023

One alternative way to reduce the use of natural aggregate and asphalt is the use of recycled materials of old road pavement or Reclaimed Asphalt Pavement (RAP). The asphalt within the RAP generally had become stiffer due to ageing, therefore it needs to be mixed with a rejuvenating agent. An alternative organic oil-based refining agent that can be used for rejuvenating rigid asphalt is Waste Cooking Oil (WCO). The purpose of this study is to analyze the characteristics of asphalt mixtures at Optimum Bitumen Content (OBC) and at best WCO content. The asphalt mixture manufacturing method used was Marshall Method. The variation of RAP materials was 25% and 50%, with added aggregate material to meet the ideal mid gradation. For each variation of RAP content, was produced mixtures with variation of of 2%, 4%, 6%, 8%, and 10% (by weight of total asphalt) where for each of those variation of RAP with variations of WCO rejuvinating materials, were made asphalt content variation of 5%; 5.5%; 6%; 6.5%; and 7%, then the OBC was determined. For the mixture with 50% RAP, the OBC was 6.3%, with best result on 8% WCO. On misture with 25% RAP the OBC was 6.2%, with best result on 4% WCO. The Marshall characteristics met the specifications. The mixture of 50% RAP with 8% WCO has lower stiffness and deformation resistance, however the performance of this mixtre was good enough on fatigue test.
Genetic evaluation and germplasm identification analysis on ITS2, trnL-F, and psbA-trnH of alfalfa varieties germplasm resources
Authors: Yong Wang , Chunbo Xu , Laga Tong , Xiaoming Zhang , Mingjiu Wang 
Published: March 2023

Abstract
In this study, genetic diversity and germplasm identification of 28 alfalfa germplasm cultivars materials were evaluated by analyzing their internal transcribed spacer 2 (ITS2), trnL-F, and psbA-trnH sequences to provide the innovative reference of alfalfa varieties genetic diversity and identify research. The results showed that the fragment average length of ITS2, trnL-F, and psbA-trnH sorting sequences were 455.7 bp, 230.3 bp, and 345.6 bp, respectively. The ITS2 sequence was too conservative to reflect the individual differences between intercultivars and intracultivars in the preliminary experiment. Furthermore, trnL-F and psbA-trnH sequence differences were relatively small between intercultivars but significant between intracultivars. Alfalfa cultivars were divided into four groups by sequence similarity clustering. Alfalfa cultivars trnL-F and psbA-trnH sequences have apparent differences, showing that chloroplast conservative sequences were independent evolution. Compared with trnL-F and psbA-trnH sequences of alfalfa cultivars, psbA-trnH sequence has abundant variation sites and can better reflect the differences between cultivars than the trnL-F sequence. Therefore, the psbA-trnH sequence can identify different alfalfa cultivars and establish the DNA sequence fingerprint.
Pre-service teachers’ views on chemistry of fine art materials of cultural heritage
Authors: Potočnik Robert , Devetak Iztok 
Published: March 2023

Abstract
The chemistry and cultural heritage can be integrated in an interdisciplinary way into teaching the Chemistry, from primary to secondary school and university, including learning about the specifics of works of art in the context of their preservation or care. The main purpose of this study is to determine the pre-service Chemistry, Primary school, and Fine art teachers’ views about promoting an interest in the cultural heritage and Chemistry learning through materials of work of art from the chemistry perspective. The study revealed that pre-service teachers do not have sufficient knowledge and experience regarding cultural heritage from the point of view of chemistry (materials and techniques of fine art), and all groups show an interest in the mentioned contents. This integrated and interdisciplinary approach to teach Chemistry and cultural heritage is presented to the pre-service teachers as part of the general elective course that was developed on the basis of this preliminary research about pre-service teachers’ views regarding these topics.
Semi-Hyers-Ulam-Rassias stability for an integro-differential equation of order 𝓃
Authors: Inoan Daniela , Marian Daniela 
Published: March 2023

Abstract
The Laplace transform method is applied in this article to study the semi-Hyers-Ulam-Rassias stability of a Volterra integro-differential equation of order n, with convolution-type kernel. This kind of stability extends the original Hyers-Ulam stability whose study originated in 1940. A general integral equation is formulated first, and then some particular cases (polynomial function and exponential function) for the function from the kernel are considered.
The Politics of Silence: Hannah Arendt and Future Generations’ Fight for the Climate
Authors: Colombo Esmeralda 
Published: March 2023

Abstract
Silence, a political category in democratic theory, has proven starkly unjust toward future generations, who are practically voiceless in intergovernmental fora, a notable feature of the international climate regime. This article first explores the status of future generations’ fight for the climate by articulating the solidarity implications of climate change as a common concern of humankind. Second, the analysis offers a brief overview of the recent constitutionalization trend concerning future generations’ interests in the environment as a meaningful counterweight to the politics of silence. Third, the article discusses climate change litigation as a catalyst of the constitutionalization trend and a proxy for political participation. Throughout the analysis, the article turns to the thought of political theorist Hannah Arendt to illustrate the potential of legally protecting future generations’ role in fighting for a stable climate through post-sovereign constitutionalism. By way of a case study, the analysis argues that in Neubauer et al
v Germany Germany’s Federal Constitutional Court offered practical ways to offset the politics of silence and increase the political space for future freedoms. Conclusively, the article offers a snapshot of open and fluid post-sovereign constitutional institutions and participative practices that could advance freedoms for future generations.
Enriched environment can reverse chronic sleep deprivation-induced damage to cellular plasticity in the dentate gyrus of the hippocampus
Authors: Shixing Xue , Xueyan Hou , Yuan Ren , Wei Tang , Wei Wang 
Published: March 2023

Abstract

Objective
We studied whether enriched environment (EE), a classic epigenetics paradigm, can prevent cellular plasticity damage caused by chronic sleep deprivation (SD).

Methods
We performed SD in mice by a modified multi-platform method (MMPM). Mice in the SD group were deprived of sleep for 18 h a day. In addition, half of the mice in the chronic SD group were exposed to EE stimuli for 6 h per day. Immunostaining analyzed neurogenesis and neural progenitor cell-differentiated phenotypes in the hippocampal dentate gyrus (DG) region.

Result
At 13 weeks, compared with the control group, SD severely impaired the proliferation and differentiation of neural stem cells, and EE completely reversed the process. SD can induce gliosis in the mouse hippocampus, and EE can delay the process.

Conclusion:
Our results suggest that chronic SD may damage the neurogenesis in the DG of the hippocampus. However, enrichment stimulation can reverse the processing by promoting neuronal repair related to neuronal plasticity.
The representational similarity between visual perception and recent perceptual history
Authors: Luo Junlian , Collins Thérèse 
Published: March 2023

From moment to moment, the visual properties of objects in the world fluctuate due to external factors like ambient lighting, occlusion and eye movements, and internal (proximal) noise. Despite this variability in the incoming information, our perception is stable. Serial dependence, the behavioral attraction of current perceptual responses towards previously seen stimuli, may reveal a mechanism underlying stability: a spatio-temporally tuned operator that smoothes over spurious fluctuations. The current study examined the neural underpinnings of serial dependence by recording the electroencephalographic (EEG) brain response of female and male human observers to prototypical objects (faces, cars and houses) and morphs that mixed properties of two prototypes. Behavior was biased towards previously seen objects. Representational similarity analysis revealed that responses evoked by visual objects contained information about the previous stimulus. The trace of previous representations in the response to the current object occurred immediately upon object appearance, suggesting that serial dependence arises from a brain state or set that precedes processing of new input. However, the brain response to current visual objects was not representationally similar to the trace they leave on subsequent object representations. These results reveal that while past stimulus history influences current representations, this influence does not imply a shared neural code between the previous trial (memory) and the current trial (perception).Significance statementThe perception of visual objects is pulled towards instances of that object seen in the recent past. The neural underpinnings of this serial dependence remain to be fully investigated. The present study examined EEG responses to faces, cars and houses, and ambiguous between-category morphs. With representational similarity analysis, we showed (1) object-specific neural patterns that differentiate the three categories; (2) that the response to the current object contains information about the previous object, mirroring behavioral serial dependence; (3) that the object-specific neural pattern about the past was different from that in the current response, revealing that while past stimulus history influences current representations, this does not imply a shared neural code between the previous trial (memory) and the current trial (perception).