bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sequential Architecture Induced Strange Dielectric‐Magnetic Behaviors in Ferromagnetic Microwave Absorber
Authors: Pan Fei , Ning Mingqiang , Li Zhenhua , Batalu Dan , Guo Hongtao , Wang Xiao , Wu Hongjing , Lu Wei 
Published: March 2023

AbstractThe high filler loading (FL) is a bottleneck in developing lightweight ferromagnetic microwave absorbers (MAs) for the actual applications. Sequential architecture design of MAs can induce strange physical behaviors due to the unique coupling‐enhancement effect between functional units, providing a vast potential for achieving high microwave absorption performance. However, the FLs of current sequential MAs fail to be designed on demand because the strange dielectric‐magnetic behaviors cannot be fulfilled. The influence of sequential architecture engineering on the macroscopic properties or microscopic loss mechanism still needs more exploration. Herein, based on four mesoscopic models (particles, chains, bundles, and fibers) of ferromagnetic functional units, a series of ferromagnetic MAs with different sequential architectures are prepared via a bottom‐up self‐assembly method. The fibrous samples exhibit the best microwave absorption performance (−51.3 dB, 4.12 GHz) at a breakthrough FL of 2 wt%, which is one order of magnitude less than other ferromagnetic MAs. Strange dielectric‐magnetic behaviors, including negative permittivity and heterodromous chiral vortex, occur due to functional units with lateral and fibrous configurations. Further, four special models are established to reveal the microwave attenuation evolutionary mechanism. This study clarifies the relationship between sequential architecture and strange dielectric‐magnetic behaviors, which provides new sight to understand microscopic electromagnetic loss mechanism.
Lipid‐Based Nanocarriers Enabled Oral Delivery of Oleanolic Acid Derivative DKS26 for Diabetes Management
Authors: Ban Yujuan , Chu Yuxiu , Pan Feng , Guo Zhiwei , Yang Yang , Wei Xiaoli , Li Guanghui , Qian Jun , Zhan Changyou , Zhang Jiquan , Tang Lei 
Published: March 2023

AbstractOleanolic acid derivative DKS26 has hypolipidemic, islet, and hepatoprotective effects. However, high lipophilicity and low water solubility led to DKS26 extremely low oral bioavailability. Herein, lipid‐based nanocarriers, including lipid nanodiscs (sND/DKS26) and liposomes (sLip/DKS26), are prepared to improve DKS26 oral absorption. In comparison to free DKS26 (5.81%), the absolute oral bioavailabilities are significantly increased to 29.47% (sND/DKS26) and 37.25% (sLip/DKS26) without detectable toxicity or immunogenicity even after repeated administrations. Both sND/DKS26 and sLip/DKS26 significantly reduce the feeding glucose level and the AUC of OGTT in db/db diabetic mice. Aiding by the newly developed scFv‐based nanocarrier separation methods, no intact nanocarriers are detected in blood circulation after oral administration, suggesting that both formulations are unable to penetrate the intestinal epithelium. They enhance DKS26 absorption mainly by improving intestinal cell uptake and rapid intracellular release of the payload. Since pre‐existing anti‐PEG is widely detected in humans, the present oral absorption pathway of both nanocarriers successfully avoids unfavorable immunological responses after interaction with anti‐PEG antibodies. The application of lipid‐based nanocarriers paves an efficient and safe avenue for the clinical translation and application of poorly soluble therapeutics derived from traditional Chinese medicine.
Programming 3D Curves with Discretely Constrained Cylindrical Inflatables
Authors: Baines Robert , Patiballa Sree Kalyan , Gorissen Benjamin , Bertoldi Katia , Kramer‐Bottiglio Rebecca 
Published: March 2023

AbstractProgramming inflatable systems to deform to desired 3D shapes opens up multifarious applications in robotics, morphing architecture, and interventional medicine. This work elicits complex deformations by attaching discrete strain limiters to cylindrical hyperelastic inflatables. Using this system, a method is presented to solve the inverse problem of programming myriad 3D centerline curves upon inflation. The method entails two steps: first, a reduced‐order model generates a conceptual solution giving coarse indications of strain limiter placement on the undeformed cylindrical inflatable. This low‐fidelity solution then seeds a finite element simulation nested within an optimization loop to further tune strain limiter parameters. We leverage this framework to achieve functionality through a priori programmed deformations of cylindrical inflatables, including 3D curve matching, self‐tying knotting, and manipulation. The results hold broad significance for the emerging computational design of inflatable systems.
Nitrogen fertilization impact on hemp (Cannabis sativa L.) crop production: A review
Authors: Kaur Navdeep , Brym Zachary , Oyola Luis Alberto Monserrate , Sharma Lakesh K. 
Published: March 2023

AbstractRegained interest in hemp cultivation has created opportunities and challenges, especially regarding crop management, for example, fertilizer application rate. Most of the literature on nitrogen (N) management in hemp production is from Asia and Europe, with more established cropping systems than in North America. Through our review, we found evidence that N fertilizer has a noticeable positive impact on basic crop morphology and physiology parameters, or at least the crop responds to such infield fertilizer applications. Some physiological parameters that show positive response include photosynthetic pigments, N and nitrate concentration, and water use efficiency. N fertilizer has been demonstrated to increase stem and fiber yield but reduce fiber quality. Increasing N also appears to increase seed yield and protein content. Both excess and low rates of N fertilizer are detrimental to floral hemp. There is little evidence that Δ9‐tetrahydrocannabinol concentration is more affected by N fertilization than genetics. The impact of fertilizer source and timing remains a critical area for research. There is still a need for research on developing a sustainable nutrient management program for hemp.
Pandemic pricing: Evidence from German grocery e‐commerce
Authors: Fedoseeva Svetlana , Van Droogenbroeck Ellen 
Published: March 2023

AbstractThe sudden demand spike for online grocery purchases during the Covid‐19 pandemic and supply bottlenecks caused by disrupted global value chains put immense pressure on prices. We analyze the prices of the largest German online grocers to test how these challenges affected prices during the first wave of the pandemic. Using a large dataset of online price quotes, we shed light on the magnitude of price changes across retailer types, product categories, and stages of the pandemic. We show that online prices went up as the intensity of Covid‐19 containment measures increased. The magnitude of price increases was heterogeneous across retailers and product categories: pure online retailers showed a lower price response compared to hybrid stores, while the prices of essential food items such as baby foods and pantry products increased more than those of other product categories or beverages. [EconLit Citations: E31, Q31].
Metal‐Free Catalytic Reduction of Amides: Recent Progress
Authors: Lee Chung Whan , Ko Haye Min 
Published: March 2023

AbstractAmines are one of the most important functional groups in organic synthesis, particularly in scaffolds constituting the active ingredients of natural products, pharmaceutical molecules, and agrochemicals. Among various transformations to access amines, amide reduction has been considered as the most facile and efficient strategy, but it is also one of the most problematic, often requiring the use of highly reactive stoichiometric reductants, such as lithium aluminum hydride, as well as rare transition metal catalysts, or both, and harsh reaction conditions. This review covers recent advances in the catalytic reduction of amides to amines without the need for metal catalysts, thus overcoming such problems.
Neuroanatomical study of the podocnemidid turtle Neochelys arenarum (Pleurodira), from the early Eocene of France
Authors: Martín‐Jiménez Marcos , Pérez‐García Adán 
Published: March 2023

AbstractNeochelys is an exclusively European Eocene podocnemidid genus belonging to a linage that reached this continent at the early Eocene. The so far available anatomical information about it is relatively abundant, especially considering that of its shell, at least partially preserved for the eight valid species currently considered. By contrast, the skull of very few representatives of the taxon has been identified. Neochelys arenarum is one of the species for which the cranial anatomy is known. It corresponds to the oldest species of this genus, coming from the MP7 zone of the Ypresian (early Eocene) of Southern France. The 3D virtual cranial reconstruction and the detailed neuroanatomical study of a representative of Neochelys are carried out here for the first time based on that species, this being also the first study of this nature performed for a European podocnemidid. In addition, the comparison of the neuroanatomical structures (i.e., the endocranial and labyrinthic cavities, and the nervous and circulatory canals) of N. arenarum with those of other representatives of Podocnemidoidae has been achieved.
Bacteriolytic activity in saliva of the hematophagous Triatoma infestans (Reduviidae) and novel characterization and expression site of a third lysozyme
Authors: Meiser Christian K. , Klenner Lars , Balczun Carsten , Schaub Günter A. 
Published: March 2023

AbstractSaliva of hematophagous insects contains many different compounds, mainly acting as anticoagulants. Investigating the bacteriolytic compounds of the saliva of the bloodsucking Triatoma infestans photometrically between pH 3 and pH 10 using unfed fifth instars and nymphs up to 15 days after feeding, we found bacteriolytic activity against lyophilized Micrococcus luteus was stronger at pH 4 and pH 6. After feeding, the activity level at pH 4 was unchanged, but at pH 6 more than doubled between 3 and 7 days after feeding. In zymographs of the saliva and after incubation at pH 4, bacteriolytic activity against Micrococcus luteus was present at eight lysis zones between 14.1 and 38.5 kDa, showing the strongest activity at 24.5 kDa. After incubation at pH 6, lysis zones only appeared at 15.3, 17, and 31.4 kDa. Comparing zymographs of the saliva of unfed and fed nymphs, bacteriolytic activity at 17 kDa increased after feeding. In total nine lysis bands appeared, also at >30 kDa, so far unreported in the saliva of triatomines. Reverse transcription polymerase chain reaction using oligonucleotides based on the previously described lysozyme gene of T. infestans, TiLys1, verified expression of genes encoding TiLys1 and TiLys2 in the salivary glands, but also of an undescribed third lysozyme, TiLys3, of which the cloned cDNA shares characteristics with other c‐type lysozymes of insects. While TiLys1 was expressed in the tissue of all three salivary glands, transcripts of TiLys2 and of TiLys3 seem to be present only in the gland G1 and G3, respectively.
Can online interview efficiently recruit graduate students during COVID‐19 pandemic?
Authors: Zhong Lichao , Jin Hui , Shen Jie 
Published: March 2023

AbstractChina is facing its largest COVID‐19 outbreaks since the early days of the pandemic. This makes on‐site interview impossible for graduate student admission. How to do online interview efficiently in recruiting graduate students is a question. Here I sort out the experience and feelings.
A RP‐HPLC–DAD method for analysis of Brazilian southeast brown propolis and its leishmanicidal properties
Authors: Ribeiro Victor Pena , Aldana‐Mejia Jennyfer Andrea , Arruda Caroline , Candido Ana Carolina Bolela Bovo , Magalhães Lizandra Guidi , Oliveira Nicoli Dias , Veneziani Rodrigo Cassio Sola , Bastos Jairo Kenupp , Ambrósio Sérgio Ricardo 
Published: March 2023

AbstractPropolis is a natural product of great economic and pharmacological importance. The flora surrounding the bee communities is a determining factor in the composition of propolis and therefore in its biological and medicinal properties. Brown propolis is one of the most important types of propolis in Brazil, produced in the southeastern region. The ethanolic extract of a brown propolis sample from Minas Gerais state was chemically characterized for the subsequent development of a RP‐HPLC method, validated according to the standards of regulatory agencies. The leishmanicidal activity of this extract was assessed. The brown propolis was characterized by the presence of chemical markers reported on green propolis such as ferulic acid, coumaric acid, caffeic acid, cinnamic acid, baccharin, artepillin and drupanin, indicating a probable origin on Baccharis dracunculifolia. The developed method agreed with the parameters established by the validation guidelines, then proved to be reliable for the analysis of this type of propolis. The brown propolis displayed significant activity against Leishmania amazonensis with IC50 values of 1.8 and 2.4 μg/ml against the promastigote and amastigote forms, respectively. The studied propolis exhibited promising evidence for use as a natural source against L. amazonensis.
Hydrogen Atom Transfer for C(sp3)−H Functionalization Enabled by Photoredox/Thianthrene/Methanol Synergistic Catalysis
Authors: Zhang Xiaoyi , Ning Shen , Li Yi , Xiong Yanjiao , Wu Xuesong 
Published: March 2023

AbstractA synergetic catalytic system of organophotocatalyst 4CzIPN, thianthrene, and methanol was developed for visible‐light‐induced Giese reactions of various alkanes and alkenes, upon using alkoxy radicals as hydrogen atom transfer reagents. The reaction can be performed under mild conditions to provide the alkylated products in moderate to excellent yields, avoiding the use of any strong oxidants and transition metal reagents. Different from the known LMCT and PCET processes, the key to success of this approach is the in situ thianthrenation of methanol by thianthrene radical cation to trigger the generation of methoxy radical.
Efficient Demulsification of Heavy Crude Oil Emulsions Using Bio‐Based Amphiphilic Esters
Authors: Abdullah Mahmood M. S. , Al-Lohedan Hamad A. , Karami Abdelnasser 
Published: March 2023

AbstractAbietic acid (AA) as a natural compound is used to synthesize two amphiphilic esters. AA was reacted with tetraethylene glycol (TG) or polyethylene glycol (PEG‐400) to obtain amphiphilic esters, AA‐TG, and AA‐PG, respectively. AA‐TG and AA‐PG were characterized using different techniques. In addition, the efficacy of these esters in demulsifying water‐in‐heavy crude oil emulsions was evaluated by means of several parameters. The demulsification efficacy (DE) of AA‐TG and AA‐PG reached 100 % in different cases. The results indicated that the DE was improved as the demulsifier concentration and temperature increased and the seawater ratio decreased. Furthermore, AA‐TG and AA‐PG achieved a higher DE and shorter demulsification time than the commercial demulsifier.
Systemic Analysis of the Spatiotemporal Changes in Multi‐Species Electroactive Biofilms to Clarify the Gradual Decline of Current Generation in Microbial Anodes
Authors: Martinez Ostormujof Lucila , Teychené Sébastien , Achouak Wafa , Fochesato Sylvain , Bakarat Mohamed , Rodriguez‐Ruiz Isaac , Bergel Alain , Erable Benjamin 
Published: March 2023

AbstractThe decrease in the electrochemical activity of multi‐species microbial anodes in bioelectrochemical systems is the main bottleneck to overcome for bringing these technologies one‐step closer to the industrialization stage. In this study, microsized stainless steel electrodes were implemented to investigate the distinctive electrochemical behavior of salt marsh electroactive biofilms (EABs). Four main temporal stages of biocolonization and electrochemical activity were thoroughly described. Maximum biofilm growth rate, high viability and high extracellular protein matrix content favored the increasing electrochemical activity of the EAB up to its maximum current peak. Then, when gradual fall in current became irreversible, biofilm growth rate decreased together with dead cells accumulation and an increase for extracellular polysaccharides. In addition, analyses of microbial populations showed a shift from Marinobacterium spp. to Desulfuromonas spp. These findings suggest a chemical and microbial temporal evolution of the EAB, which can be directly correlated to the electrochemical performance of the bioanode.
Controlling Morphologies of Redox‐Responsive Polymeric Nanocarriers for a Smart Drug Delivery System
Authors: Lee Chae Gyu , Kwon Tae‐Hyuk 
Published: March 2023

AbstractRedox‐responsive nanocarriers using disulfides or thiols have received considerable attention owing to the higher levels of glutathione (GSH) in cancer cells than those in extracellular fluids. Nevertheless, the normal‐to‐cancer‐cell selectivity of these nanocarriers has not yet been clarified. Nanocarriers exhibit different cytotoxicities depending on the morphologies they adopt under the redox‐active conditions typically existing in cancerous cells. Therefore, not only GSH levels but also reactive oxygen species (ROS) levels and other complex cancerous cell conditions must be considered for the development of smart drug delivery systems. In this article, we review the structural design of redox‐responsive polymers that exhibit different morphological changes in environments akin to cancerous cells (e. g., GSH‐ and ROS‐abundant conditions). In addition, we propose a molecular design for the spatiotemporal control of nanocarrier morphology depending on the levels of both GSH and ROS upon photoirradiation to increase the cytotoxicity difference between normal and cancer cells.
Photoluminescence Properties of Single‐Walled Carbon Nanotubes Influenced by the Tether Length of Reagents with Two Reactive Sites
Authors: Konno Yui , Morooka Rina , Morishita Tatsunari , Zhao Pei , Miyasaka Naoto , Ono Kazuki , Noda Akira , Uchida Daiki , Iwasaki Ren , Yamada Michio , Ehara Masahiro , Maeda Yutaka 
Published: March 2023

AbstractThe functionalization of single‐walled carbon nanotubes (SWNTs) is an effective method for controlling a local band gap, resulting in photoluminescence (PL) in the near‐infrared region. Herein, SWNTs were functionalized using a series of bromoalkanes and dibromoalkanes to evaluate the effects of their length on the nanotube PL properties. When bromoalkanes (CnH2n+1Br) or dibromoalkanes (CnH2nBr2) with tether lengths of six or more were utilized for six different semiconducting SWNTs, the obtained SWNT adducts exhibited two new PL peaks, whereas dibromoalkanes with tether lengths of 3–5 (CnH2nBr2: n=3–5) produced single peaks. Combined with theoretical calculations, the results suggested that the tether length of reagents changes the formation mechanism of functionalized adducts, that is, CnH2nBr2 (n=3–5) tends to result in kinetic products.
Rhetorical citizenship and the environment
Authors: Andersen Ida Vikøren 
Published: March 2023

AbstractIn this paper, I discuss rhetorical studies’ contribution to the study of environmental communication. With the concept of rhetorical environmental citizenship, I emphasize rhetorical scholarship's concern with citizens’ participation in democracy – both as recipients of and actors in environmental debates. Specifically, this approach invites analyses and evaluations of the public rhetoric of elite actors, considering how it facilitates critical engagement and reflection in matters affecting the environment. Additionally, it encourages examinations of citizens’ democratic participation, attending to how citizens perform, challenge and negotiate their membership in the community also through non‐deliberative rhetorical practices.
Plasmonic Scattering Microscopy for Label‐Free Imaging of Molecular Binding Kinetics: From Single Molecules to Single Cells
Authors: Zhang Pengfei , Zhou Xinyu , Wang Shaopeng 
Published: March 2023

AbstractMeasuring molecular binding kinetics represents one of the most important tasks in molecular interaction analysis. Surface plasmon resonance (SPR) is a popular tool for analyzing molecular binding. Plasmonic scattering microscopy (PSM) is a newly developed SPR imaging technology, which detects the out‐of‐plane scattering of surface plasmons by analytes and has pushed the detection limit of label‐free SPR imaging down to a single‐protein level. In addition, PSM also allows SPR imaging with high spatiotemporal resolution, making it possible to analyze cellular response to the molecular bindings. In this Mini Review, we present PSM as a method of choice for chemical and biological imaging, introduce its theoretical mechanism, present its experimental schemes, summarize its exciting applications, and discuss its challenges as well as the promising future.
p53 expression in cytology samples may represent a marker of early‐stage cancer
Authors: Policardo Federica , Tralongo Pietro , Arciuolo Damiano , Fiorentino Vincenzo , Cardasciani Lina , Pierconti Francesco , Carlino Angela , Curatolo Mariangela , Pontecorvi Alfredo , Fadda Guido , De Crea Carmela , Lombardi Celestino Pio , Raffaelli Marco , Larocca Luigi Maria , Pantanowitz Liron , Rossi Esther Diana 
Published: March 2023

AbstractBackgroundTP53 gene plays a major role in the negative control of cell proliferation and in the regulation of signaling cascades. TP53 mutation may have a relevant role in the malignant transformation of thyroid cells as well as thyroid tumor progression. TP53 mutation has been detected only in few well differentiated thyroid carcinomas and is absent in benign conditions.MethodsA total of 162 prospective thyroid cytology and corresponding histological samples diagnosed from atypia of indeterminate significance (AUS) to malignant, were studied via immunocytochemistry for p53. Hence, 50 benign lesions (B) were used as negative control. Molecular analysis for p53 only was performed.ResultsThe cytology resulted in 50 B, 48 AUS, 40 follicular neoplasms (FNs), 23 suspicious for malignancy (SFM), and 1 malignant (M) case. The authors reported 102 negative and 60 positive p53 cases. The 60 positive cases included 27 cases with weak and/or focal cytoplasmic positivity (+1) and 33 with cases moderate (2+) to strong (3+) cytoplasmic and/or nuclear expression. Overall, 71 cases had histology (2 B, 11 AUS, 37 FN, 20 SFM, and 1 M) including 61.7% benign and 38.2% malignant diagnoses. Only 16 of 71 (5 FN, 10 SFM, and 1 M) were p53‐positive. Furthermore, 100% AUS and 86.5% FN cases were p53‐negative, none of which had malignant histology. All p53‐positive cases were associated with a larger nodule size, tall‐cell variant subtype, multifocality, extra thyroidal infiltration, and nodal metastases. Noninvasive follicular thyroid neoplasm with papillary like nuclear features were negative for p53. Few discrepancies in p53 intensity were observed on histology; there were no differences with the molecular testing.Conclusionsp53 might be useful in discriminating thyroid follicular lesions. p53 is likely to be a useful diagnostic marker in recognizing indeterminate lesions that are well‐differentiated thyroid cancers.