bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between depressive mood and chronic periodontitis among senior residents using the National Health Insurance Service‐Senior Cohort Database
Authors: Kim Yu‐Rin , Son Minkook , Nam Seoul‐Hee 
Published: December 2022

AbstractBackgroundBacteria involved in chronic periodontal disease induce inflammatory cytokines. These cytokines can enter the brain through systemic circulation and cause depression. In this study, we investigated the association between depressed mood and chronic periodontitis in older adults in Korea.MethodsThis study used data from the Life‐changing Period Health Checkup (2007–2008), performed only at 66 years of age, which is available from the National Health Insurance Service‐Senior Cohort Database. The depressed mood status was evaluated by three questions in the mental health examination. The definition of chronic periodontitis was determined based on the diagnosis and treatment codes for chronic periodontitis. Based on the three questions, we investigated the association between depressive mood and chronic periodontal disease by dividing the study population into 9622 depressed mood subjects (DMS) and 9091 non‐depressed mood subjects (NDMS). Multivariable‐adjusted logistic regression analysis was performed, and odds ratios (ORs) with 95% confidence intervals (95% CIs) were presented.ResultsAmong the NDMS, 5390 patients with chronic periodontitis were identified, and among the DMS, 5964 patients with chronic periodontitis were identified. The crude OR (95% CI) for chronic periodontitis in DMS compared to NDMS was 1.12 (1.06–1.19). The adjusted OR (95% CI) for chronic periodontitis was 1.12 (1.06–1.19). As a result of confirming the effect of sex and comorbidity on the association between depressed mood and chronic periodontitis, a significant association was observed for women at 1.15 (1.07–1.25). In addition, the adjusted OR (95% CI) for depressive mood and chronic periodontitis was 1.15 (1.07–1.25) for patients with hypertension, 1.13 (1.03–1.25) for patients with diabetes, 1.12 (1.02–1.22) for patients with dyslipidemia, and 1.18 (1.04–1.34) for patients with heart disease.ConclusionsThis study confirmed the relationship between depressed mood and chronic periodontitis in older adults. Therefore, education to strengthen the emotional management of older adults, especially with respect to depression, would play an auxiliary role in preventing and treating periodontitis.
3D bioprinting and its innovative approach for biomedical applications
Authors: Tripathi Swikriti , Mandal Subham Shekhar , Bauri Sudepta , Maiti Pralay 
Published: December 2022

Abstract3D bioprinting or additive manufacturing is an emerging innovative technology revolutionizing the field of biomedical applications by combining engineering, manufacturing, art, education, and medicine. This process involved incorporating the cells with biocompatible materials to design the required tissue or organ model in situ for various in vivo applications. Conventional 3D printing is involved in constructing the model without incorporating any living components, thereby limiting its use in several recent biological applications. However, this uses additional biological complexities, including material choice, cell types, and their growth and differentiation factors. This state‐of‐the‐art technology consciously summarizes different methods used in bioprinting and their importance and setbacks. It also elaborates on the concept of bioinks and their utility. Biomedical applications such as cancer therapy, tissue engineering, bone regeneration, and wound healing involving 3D printing have gained much attention in recent years. This article aims to provide a comprehensive review of all the aspects associated with 3D bioprinting, from material selection, technology, and fabrication to applications in the biomedical fields. Attempts have been made to highlight each element in detail, along with the associated available reports from recent literature. This review focuses on providing a single platform for cancer and tissue engineering applications associated with 3D bioprinting in the biomedical field.
SOX2‐positive retinal stem cells are identified in adult human pars plicata by single‐cell transcriptomic analyses
Authors: Wang Xiaotang , Fan Wei , Xu Zongren , Zhang Qi , Li Na , Li Ruonan , Wang Guoqing , He Siyuan , Li Wanqian , Liao Dan , Zhang Zhi , Shu Nan , Huang Jiaxing , Zhao Chenyang , Hou Shengping 
Published: December 2022

AbstractStem cell therapy is a promising strategy to rescue visual impairment caused by retinal degeneration. Previous studies have proposed controversial theories about whether in situ retinal stem cells (RSCs) are present in adult human eye tissue. Single‐cell RNA sequencing (scRNA‐seq) has emerged as one of the most powerful tools to reveal the heterogeneity of tissue cells. By using scRNA‐seq, we explored the cell heterogeneity of different subregions of adult human eyes, including pars plicata, pars plana, retinal pigment epithelium (RPE), iris, and neural retina (NR). We identified one subpopulation expressing SRY‐box transcription factor 2 (SOX2) as RSCs, which were present in the pars plicata of the adult human eye. Further analysis showed the identified subpopulation of RSCs expressed specific markers aquaporin 1 (AQP1) and tetraspanin 12 (TSPAN12). We, therefore, isolated this subpopulation using these two markers by flow sorting and found that the isolated RSCs could proliferate and differentiate into some retinal cell types, including photoreceptors, neurons, RPE cells, microglia, astrocytes, horizontal cells, bipolar cells, and ganglion cells; whereas, AQP1− TSPAN12− cells did not have this differentiation potential. In conclusion, our results showed that SOX2‐positive RSCs are present in the pars plicata and may be valuable for treating human retinal diseases due to their proliferation and differentiation potential.
Evaluation of muscle loss by ultrasonography in critically ill patients
Authors: Mendes Jucicléia Nathália da Silva , Rodrigues Isa Galvão , Arcoverde Gabriela Maria Pereira Floro , Floro Caio Cesar Pereira , Fortunato Wenize Suyane Lopes , Lima Roberta Maria da Silva , Pinho Cláudia Porto Sabino 
Published: December 2022

AbstractBackgroundCritically ill patients have intense muscle tissue mobilization, and attenuating protein catabolism may contribute to improved outcomes.ObjectiveTo evaluate short‐term muscle loss in critically ill patients.MethodsIn this prospective observational study, we evaluated the thickness of the rectus femoris muscle by ultrasonography in young and older adults of both sexes admitted to a cardiological intensive care unit within 48 h of admission (baseline) and after 7 days. The results were compared and correlated with anthropometric, clinical, and biochemical parameters. The significance level for all statistical analyses was 0.05.ResultsThe final sample comprised 88 patients with a mean age of 66.2 ± 11.8 years. There was an average 13.5% reduction in rectus femoris muscle thickness over the study period (P < 0.001), regardless of the thigh circumference maintenance (P = 0.229). This reduction occurred even with improved clinical parameters (C‐reactive protein, Simplified Acute Physiology Score) and was greater in patients receiving mechanical ventilation and sedation and in those who died. Regarding nutrition status, malnourished and eutrophic individuals showed greater muscle loss than overweight individuals. There was also an inverse correlation of muscle loss (percentage) with body mass index, arm circumference, and calf circumference (P < 0.05), demonstrating that the lower these anthropometric measurements, the higher the muscle loss obtained by ultrasound.ConclusionUltrasonography assessment detected muscle mass loss in the short‐term more sensitively than the anthropometric method. However, it demands caution and further studies demonstrating this analysis.
Innovative strategy to improve enteral nutrition in prone positioning with patients with COVID‐19
Authors: Powers Jan , Richardson Janette , Rechter Jennifer 
Published: December 2022

AbstractBackgroundEnteral nutrition is essential to improve outcomes in patients who are critically ill. Patients in the prone position, including those diagnosed with coronavirus disease 2019 (COVID‐19) present additional challenges for enteral nutrition initiation.MethodsA novel technique for placing feeding tubes while in the prone position was developed using an electromagnetic placement device and specialty trained clinical nurse specialists. Data were assessed retrospectively to determine effectiveness of this new practice.ResultsSixty‐eight patients had feeding tubes placed while in the prone position; 75% were able to be placed through the postpyloric route, 22% were placed through the gastric route, and 3% unable to be placed. Use of this technique facilitated earlier initiation of feedings by 2 days from time of admission and almost half a day from intubation to feeding. There was no additional radiation exposure from using this technique.ConclusionAbility to place feeding tubes early while patients were prone reduced delays for starting enteral nutrition. Patients with COVID‐19 in the prone position were able to receive effective nutrition support earlier with no additional complications.
Value of social activities and prerequisites for continued participation of rural older adults: A qualitative study
Authors: Onishi Ryuta , Takashima Risa , Saeki Kazuko , Hirano Michiyo 
Published: December 2022

AbstractAimsTo explore the value of social activities and the prerequisites for continuous participation among rural older adults based on their experiences.DesignQualitative, descriptive design.MethodsIndividual semi‐structured interviews were conducted with 14 older adults from voluntary community salons in a rural area in Japan. Participants were selected through purposeful sampling. Data were analyzed using qualitative content analysis. The consolidated criteria for reporting qualitative research (COREQ) checklist were used.ResultsFour values of social activities were identified: “Mutual benefit connectedness,” “Preventing and coping with aging,” “Making life brilliant ‘now’,” and “Building a safety net.” Three prerequisites for activities were identified: “Do not overreach,” “Do not infringe on personal territory,” and “Do not go against community norms.” Social activities provide rural older adults with reciprocity ties, coping with aging, enhanced daily lives, and a social safety net. Continued participation in rural social activities requires adherence to cultural norms and moderation of relationship distances. Community and public health nurses are expected to promote social activities that incorporate these values and adhere to these prerequisites.
Remote motivational interviewing to improve patient self‐care and caregiver contribution to self‐care in heart failure (REMOTIVATE‐HF): Rationale, design, and methodology for a multicentre randomized controlled trial
Authors: Vellone Ercole , Rebora Paola , Iovino Paolo , Ghizzardi Greta , Baricchi Marina , Alvaro Rosaria , Sili Alessandro , Barello Serena , Ausili Davide , Trenta Alessia M. , Pedroni Cristina , Dellafiore Federica , Arrigoni Cristina , Riegel Barbara , Caruso Rosario 
Published: December 2022

AbstractIn patients with heart failure (HF), self‐care, and caregiver contribution to self‐care (i.e., the daily management of the disease by patients and caregivers) are essential for improving patient outcomes. However, patients and caregivers are often inadequate in their self‐care and contribution to self‐care, respectively, and struggle to perform related tasks. Face‐to‐face motivational interviewing (MI) effectively improves self‐care and caregiver contribution to self‐care, but the evidence on remote MI is scarce and inconclusive. The aims of this randomized controlled trial will be to evaluate whether remote MI performed via video call in patients with HF: (1) is effective at improving self‐care maintenance in patients (primary outcome); (2) is effective for the following secondary outcomes: (a) for patients: self‐care management, self‐care monitoring, and self‐efficacy; HF symptoms; generic and disease‐specific quality of life; anxiety and depression; use of healthcare services; and mortality; and (b) for caregivers: contribution to self‐care, self‐efficacy, and preparedness. We will conduct a two‐arm randomized controlled trial. We will enroll and randomize 432 dyads (patients and their informal caregivers) in Arm 1, in which patients and caregivers will receive MI or, in Arm 2, standard care. MI will be delivered seven times over 12 months. Outcomes will be assessed at baseline and 3 (primary outcome), 6, 9, and 12 months from enrollment. This trial will demonstrate whether an inexpensive and easily deliverable intervention can improve important HF outcomes. With the restrictions on in‐person healthcare professional interventions imposed by the COVID‐19 pandemic, it is essential to evaluate whether MI is also effective remotely.
An examination of primary health care nursing service evaluation using the Donabedian model: A systematic review
Authors: McCullough Kylie , Andrew Lesley , Genoni Angela , Dunham Melissa , Whitehead Lisa , Porock Davina 
Published: December 2022

AbstractNurses are key to the delivery of global primary health care services. However, there appears to be a lack of evaluation of primary health care nursing delivery models in the published literature. This evaluation is vital to the improvement of patient experiences, national and global health outcomes, and the justification of future investment in primary health care nursing services. The purpose of this review was to explore and analyze the literature that reports on the evaluation of primary health care nursing services, to ascertain the nature and utility of these evaluation methods, and identify opportunities for future research in this area. A systematic review of the published literature was conducted following PRISMA guidelines, using the databases CINAHL, Joanna Briggs Institute, MEDLINE, and Proquest. Thirty‐two articles published between 2010 and 2022 were selected. Results were organized using the Donabedian model. A paucity of research into the evaluation of nurse‐led primary health care services was noted. Where evident, evaluation of primary health care nursing services tended to reflect the medical model. Medical outcomes measures dominated evaluation criteria including diagnosis rates, prescription costs, and disease outcomes. Primary health care principles such as service accessibility, cultural appropriateness, and availability were rarely used. The perspectives and experiences of nurses were not sought in service evaluation, including most of the nurse‐led services. Development of an evidence‐base of nursing primary health care services that are informed by the nursing experience and apply a framework of universal primary health care principles across the structure, process, and outcomes aspects of the service is recommended.
Information for climate finance accountability regimes: Proposed framework and case study of the Green Climate Fund
Authors: Basak Rishi , Karlsson‐Vinkhuyzen Sylvia , Termeer Katrien J. A. M. 
Published: December 2022

AbstractThis paper addresses the role performance information plays in the accountability regimes of international climate change financing institutions and how this can be improved. It has been argued that the quality of the performance information of projects financed by public and private sources, as well as how that information is used, influences decisions made by the various actors in the accountability regimes, including the ability to hold actors to account. A theory‐based framework is developed to analyze and enable the improvement of the information produced and used in climate finance accountability regimes. The framework is tested by applying it to the Green Climate Fund via document analysis and key informant interviews. With the help of the framework, gaps are identified, and improvements are suggested so that account holders and account givers can better fulfill their respective roles in the given accountability regime.
Habitual walking speed and fatigue explain self‐reported functional capacity after stroke
Authors: Polese Janaine Cunha , Albuquerque Thaís Bueno Dias , Faria‐Fortini Iza , Teixeira‐Salmela Luci Fuscaldi 
Published: December 2022

AbstractIntroductionIndividuals after stroke present several motor impairments, which reduced the functional capacity. The understanding of modifiable factors which are related to functional capacity in individuals with chronic stroke could better direct clinical practice. However, the mechanisms that could influence functional capacity in individuals with chronic stroke are not fully understood.ObjectiveThis study aimed to determine which modifiable variables would best predict self‐reported functional capacity after stroke.DesignCross‐sectional.SettingResearch laboratory setting.ParticipantsNinety two individuals with chronic stroke, who had a mean age of 60 (SD 13) years and a time since the onset of the stroke of 52 (67) months.Main Outcome MeasuresRegression analysis of cross‐sectional data was used to investigate whether body mass index, habitual walking speed, physical activity levels, fatigue, motor recovery, walking distance, and residual strength deficits of the lower limb muscles would predict self‐reported functional capacity.ResultsHabitual walking speed alone explained 48% of the variance in functional capacity. When fatigue was included in the model, the explained variance increased to 55%.ConclusionsHabitual walking speed and fatigue were significant predictors of self‐reported functional capacity in individuals with chronic stroke. These individuals may increase their functional capacity with interventions aimed at increasing walking speed and reducing fatigue.
Robotic resection of paediatric solid tumours at a single institution
Authors: Pu Jiarui , Li Hang , Liu Yuan , Hong Mei , Li Shiwang , Tang Shaotao 
Published: December 2022

AbstractBackgroundTo explore the clinical application of robotic‐assisted surgery in paediatric solid tumours and to explore its feasibility.MethodsFrom 2015 to 2022, 53 children with solid tumours underwent robotic‐assisted surgery in our centre were retrospectively analysed.ResultsThe mean weight of the patients was 27.7 kg, and the mean age was 6.7 years. The average tumour volume was 5.5*4.6*3.7 cm. Two procedures (3.8%) were converted. The mean total operative time was 198.5 min. The mean estimated blood loss was 27.1 ml, and no intraoperative complications occurred. Two (3.8%) patients had postoperative complications. At a median follow‐up of 21.2 months, one (1.9%) patient with malignant tumours stopped treatment, and two (3.8%) patients developed tumour recurrence.ConclusionsRobotic‐assisted tumour resection is feasible in highly selected cases of young age, light weight, huge tumour or malignant tumour.
Numerical simulation of transport phenomena and its effect on the weld profile and solute distribution during laser welding of dissimilar aluminium alloys with and without beam oscillation
Authors: Mohan Anand , Franciosa Pasquale , Ceglarek Dariusz , Auinger Michael 
Published: December 2022

Abstract
Remote Laser Welding (RLW) of Aluminium alloys has significant importance in lightweight manufacturing to decrease the weight of the body in white. It is critical to understand the physical process of transport phenomena during welding which is highly related to the mechanical performance of the joints. To investigate the underlying physics during welding and to understand the influence of beam oscillation on heat transfer, fluid flow and material mixing a transient three-dimensional Finite Element (FE) based Multiphysics model has been developed and validated from the experiments. The effect of welding speed, oscillation amplitude and oscillation frequency on the fusion zone dimensions, flow profile, vorticity profile, cooling rate and thermal gradient during the butt welding of Al-5754 to Al-6005, with sinusoidal beam oscillation, is analysed. It was found that one additional vortex is formed during beam oscillation welding due to the churning action of the oscillating beam. With the increase in oscillation amplitude, welds become wider and the depth of penetration decreases. An increase in oscillation frequency leads to an increase in the flow rate of the molten metal suggesting that the beam oscillation introduces a churning action that leads to an increase in mixing. It was highlighted that the material mixing depends on both diffusion and convection.
Antioxidant content and volatile composition of seedless table grape (Vitis vinifera L.) varieties
Authors: Blanch Gracia Patricia , Suarez-Coca Diana , de Pascual-Teresa Sonia , del Castillo María Luisa Ruiz 
Published: December 2022

AbstractGrapes are important sources of phenolics, which are recognized to possess high biological value. In this work, we evaluated the total phenol content (TPC), total anthocyanin content (TAC), antioxidant activity (AA) and volatile composition of unstudied seedless table grape varieties (i.e., Autumn Crisp and Pristine as white cultivars, Scarlotta and Crimson as red cultivars and Adora and Melody as black cultivars). As a result, Adora and Melody exhibited higher TPCs, TACs and AA, measured by the 2,2-diphenyl-2-picrylhydrazil (DPPH) and photochemiluminescence (PCL) assays, than the rest of the varieties. A comparison between the two black cultivars proved that Adora possessed higher TPC (62.70 mg GAE 100 g−1), DPPH radical scavenging activity (IC50of 3.69 mg ml−1) and PCL antiradical activity (72.14 µg Trolox ml−1) than Melody (47.30 mg GAE 100 g−1, IC50of 5.0 mg ml−1and 42.36 µg Trolox ml−1, respectively). The volatile composition, determined by solid phase microextraction (SPME)–gas chromatography/mass spectrometry (GC/MS), indicated a similar qualitative aroma profile for all varieties. However, quantitative differences were measured among them, which were reflected in distinct sensory perception by sensorial testing. From these results, Adora was selected for its antioxidant properties and flavor characteristics.
On the Two-Point Function of the Potts Model in the Saturation Regime
Authors: Aoun Yacine , Ott Sébastien , Velenik Yvan 
Published: December 2022

AbstractWe consider the Random-Cluster model on$${\mathbb {Z}}^d$$Zdwith interactions of infinite range of the form$$J_x = \psi (x){\mathsf {\scriptstyle e}}^{-\rho (x)}$$Jx=ψ(x)e-ρ(x)with$$\rho $$ρa norm on$${\mathbb {Z}}^d$$Zdand$$\psi $$ψa subexponential correction. We first provide an optimal criterion ensuring the existence of a nontrivialsaturationregime (that is, the existence of$$\beta _{\textrm{sat}}(s)>0$$βsat(s)>0such that the inverse correlation length in the directionsis constant on$$[0,\beta _{\textrm{sat}}(s)$$[0,βsat(s))), thus removing a regularity assumption used in our previous work (Aoun et al. in Commun Math Phys 386:433–467, 2021). Then, under suitable assumptions, we derive sharp asymptotics (which are not of Ornstein–Zernike form) for the two-point function in the whole saturation regime$$(0,\beta _{\textrm{sat}}(s))$$(0,βsat(s)). We also obtain a number of additional results for this class of models, including sharpness of the phase transition, mixing above the critical temperature and the strict monotonicity of the inverse correlation length in$$\beta $$βin the regime$$(\beta _{\textrm{sat}}(s), \beta _{\mathrm {\scriptscriptstyle c}})$$(βsat(s),βc).