bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative study on the clinical outcomes and prognosis of endovascular embolization and craniotomy clipping for the treatment of cerebral aneurysms
Authors: Li Gang , Chen Shaojun , Han Jing , Pan Wanxi , Ji Ping 
Published: July 2023

Objective: To investigate the safety and outcomes of endovascular embolization and craniotomy clipping in the treatment of cerebral aneurysms.
Methods: We collected the clinical data of 106 patients with cerebral aneurysm who underwent surgical treatment (endovascular embolization, Group-A, n=55; craniotomy clipping, Group-B, n=51) in the First People’s Hospital of Yichang from January 2020 to May 2021. We compared surgical treatment indexes, treatment costs, neurological function before and after the treatment, incidence of postoperative complications and the prognosis after one-year follow-up between the two groups.
Results: Endovascular embolization (Group-A) was associated with a shorter mean operation time and hospital stay, a lower mean intraoperative bleeding amount, and a higher mean treatment cost than craniotomy clipping (Group-B) (P<0.05). Compared with the pre-operative neurological function scores, the scores of both groups decreased after the surgery, and the mean post-operative score of Group-A was significantly lower than that of Group-B (P<0.05). Compared with Group-B , patients in Group-A had a lower overall complication rate (P < 0.05. Higher proportion of patients in Group-A had a good prognosis (P < 0.05).
Conclusion: Endovascular embolization for the treatment of cerebral aneurysms is safe as it can shorten the operation time and hospital stay, reduce the incidence of neurological injury and complications, and have a favorable prognosis. However, the treatment is more expensive. Endovascular embolization can be selected for the treatment of cerebral aneurysms when economic conditions allow it.
doi: https://doi.org/10.12669/pjms.39.5.7401
How to cite this: Li G, Chen S, Han J, Pan W, Ji P. Comparative study on the clinical outcomes and prognosis of endovascular embolization and craniotomy clipping for the treatment of cerebral aneurysms. Pak J Med Sci. 2023;39(5):---------. doi: https://doi.org/ 10.12669/pjms.39.5.7401
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Case Report: Successful results of direct varicose vein ablation with EVLA in chronic venous insufficiency patient in Indonesia
Authors: Taofan Taofan , Utoh Junichi , Dakota Iwan , Indriani Suci , Abdillah Choiron , Kartamihardja Achmad Hafiedz Azis , Adiarto Suko , Sukmawan Renan 
Published: July 2023

Background: Varicose veins are considered a chronic venous disease. Delaying treatment might cause several late complications that contribute to a high burden on healthcare systems. It may be treated with endovenous laser ablation (EVLA) and stab avulsion as additional procedures. Varicose direct ablation has been promoted to replace stab avulsion in certain conditions. The purpose of this report is to describe a detailed procedure of the first successful direct varicose ablation with Utoh’s technique using EVLA without any surgical incision in a 71-year-old female presenting varicose vein. Case report: A 71-year-old female came to the outpatient clinic with a large bulging vein in her leg. Duplex ultrasound showed that the great saphenous vein (GSV) was incompetent with a varicose vein in the medial part of proximal GSV below the knee. The patient underwent EVLA with direct varicose ablation using Utoh’s technique. Duplex sonography evaluation showed the right GSV was utterly obliterated, including the varicose vein. The patient was discharged two days after the procedure without significant complaints nor pain medication. Conclusions: Direct varicose ablation was proposed as a better alternative than stab avulsion. The varicose vein can be managed with EVLA without a scalpel, incision, avulsion, or phlebectomy. In this case presentation, the endovascular therapeutical approach with Utoh’s ablation technique showed promising results, and no complication was found in the patient.
First case of meningoencephalitis and bacteraemia with Flavobacterium lindanitolerans
Authors: Zurbuchen Rebecca , de Roche Mirjam , Galimanis Aikaterini , Narr Kerstin , Dubuis Olivier , Resch Christiane , Ziaka Mairi 
Published: July 2023

Purpose: Flavobacterium lindanitolerans is an environmental Gram-negative, non-spore-forming rod which is usually not considered to be a human pathogen. Isolation from human clinical samples has been described only once. We report the first case of meningoencephalitis and bacteraemia with Flavobacterium lindanitolerans. Case description: A 76-year-old female presented with fever, headache, alteration of mental status, marked meningism and dysarthria. A lumbar puncture demonstrated cerebrospinal fluid findings consistent with bacterial meningitis, and a broad-spectrum antibiotic therapy was initiated. Blood and cerebrospinal fluid cultures revealed a growth of Flavobacterium lindanitolerans. Based on antimicrobial susceptibilities testing, antibiotic treatment was changed to levofloxacin, resulting in a remission of the clinical symptoms after 21 days of treatment. Conclusion: Flavobacterium species are extremely rare human pathogens. However, some of them have been reported to cause opportunistic infections. We describe the first case of meningoencephalitis and bacteraemia caused by Flavobacterium lindanitolerans which was effectively treated with levofloxacin for 21 days.
Immune reconstitution inflammatory syndrome in AIDS patient after successful induction of virological suppression with cabotegravir/rilpivirine
Authors: Al-Handola Rami , Chinnappan Justine , Bakeer Mohammad , Osterholzer Danielle 
Published: July 2023

Long-acting (LA) cabotegravir/rilpivirine (CAB/RPV) is a complete regimen for the management of human immunodeficiency virus type 1 (HIV-1) infection to replace their oral antiretroviral therapy (ART) when they have been virologically suppressed. We present a case of successful achievement of undetectable HIV RNA viral load levels in an acquired immunodeficiency syndrome (AIDS) patient with long-standing virologic failure within two months of CAB/RPV LA initiation. This was later complicated by immune reconstitution inflammatory syndrome (IRIS) due to Mycobacterium avium-intracellulare (MAI) infection and hepatitis B virus (HBV) reactivation.
The management of cognitive labour in same-gender couples
Authors: McLean Caitlan , Musolino Connie , Rose Alice , Ward Paul R. 
Published: July 2023

Objective
This study explored how cognitive labour as a form of unpaid, household labour is performed by people in same-gender couples.

Background
Excessive performance of unpaid labour has been associated with several health impacts. Cognitive labour (anticipating needs, identifying options for meeting needs, making decisions and monitoring progress) is an underexamined dimension of unpaid labour which has centered on the experiences of heterosexual couples.

Method
Dyadic and individual interviews were carried out to explore how cognitive labour was performed in same-gender couples between March and October 2021 using an inductive methodology. Adults who were in a same-gender couple, had lived with their partner for at least six months, were not living with children were recruited largely via social media.

Results
Examining cognitive labour performance amongst same-gender couples revealed four key themes: 1) habitually fostered patterns of trust; 2) agency in redefining family; 3) barriers to cognitive harmony; and 4) facilitators to cognitive harmony. Findings regarding the relationships between themes are presented in a narrative model. Dyadic interviews allowed for deep, narratives relating to cognitive labour performance.

Conclusions
The narrative model provides new conceptual understanding of how cognitive labour is performed outside of the heteronormative sphere. Couple’s adoption of a strengths-based frame to cognitive labour performance removed the opposition inherent in gender dichotomies. These findings support calls for research to incorporate social change to build and refine theory, including how queer and feminist movements have challenged gendered and heteronormative family and household roles.
Video-based interventions to improve self-assessment accuracy among physicians: A systematic review
Authors: Pattni Chandni , Scaffidi Michael , Li Juana , Genis Shai , Gimpaya Nikko , Khan Rishad , Bansal Rishi , Torabi Nazi , Walsh Catharine M. , Grover Samir C. 
Published: July 2023

Purpose
Self-assessment of a physician’s performance in both procedure and non-procedural activities can be used to identify their deficiencies to allow for appropriate corrective measures. Physicians are inaccurate in their self-assessments, which may compromise opportunities for self- development. To improve this accuracy, video-based interventions of physicians watching their own performance, an experts’ performance or both, have been proposed to inform their self-assessment. We conducted a systematic review of the effectiveness of video-based interventions targeting improved self-assessment accuracy among physicians.

Materials and methods
The authors performed a systematic search of MEDLINE, Embase, EBM reviews, and Scopus databases from inception to August 23, 2022, using combinations of terms for “self-assessment”, “video-recording”, and “physician”. Eligible studies were empirical investigations assessing the effect of video-based interventions on physicians’ self-assessment accuracy with a comparison of self-assessment accuracy pre- and post- video intervention. We defined self-assessment accuracy as a “direct comparison between an external evaluator and self-assessment that was quantified using formal statistical analysis”. Two reviewers independently screened records, extracted data, assessed risk of bias, and evaluated quality of evidence. A narrative synthesis was conducted, as variable outcomes precluded a meta-analysis.

Results
A total of 2,376 papers were initially retrieved. Of these, 22 papers were selected for full-text review; a final 9 studies met inclusion criteria for data extraction. Across studies, 240 participants from 5 specialties were represented. Video-based interventions included self-video review (8/9), benchmark video review (3/9), and/or a combination of both types (1/9). Five out of nine studies reported that participants had inaccurate self-assessment at baseline. After the intervention, 5 of 9 studies found a statistically significant improvement in self-assessment accuracy.

Conclusions
Overall, current data suggests video-based interventions can improve self-assessment accuracy. Benchmark video review may enable physicians to improve self-assessment accuracy, especially for those with limited experience performing a particular clinical skill. In contrast, self-video review may be able to provide improvement in self-assessment accuracy for more experience physicians. Future research should use standardized methods of comparison for self-assessment accuracy, such as the Bland-Altman analysis, to facilitate meta-analytic summation.
Perceived antimicrobial dispensing practices in medicine outlets in Ghana: A maximum difference experiment design
Authors: Nyarko Eric , Akoto Francisca Mawulawoe , Doku-Amponsah Kwabena 
Published: July 2023

Introduction
Antimicrobials are consumed among patients globally, but in developing and middle-income countries, these drugs can be obtained without a prescription from pharmacies and licensed drug stores due to inadequate regulation in the pharmaceutical sector. This study aimed to assess antimicrobial dispensing practices in medicine sales outlets (i.e., pharmacies and licensed drug stores) to provide quantitative evidence for policy discussions to enhance patient safety and care quality in Ghana’s pharmaceutical industry.

Method
The data for this study were obtained from a cross-sectional survey conducted in the Greater Accra region between July and August 2022. The survey was conducted through interviewer-administered questionnaires, and 200 staff members from medicine sales outlets were randomly selected using a two-stage cluster and random sampling technique. The maximum difference experiment model, rooted in random utility theory, was used to analyze their antimicrobial dispensing practices.

Result
We found that medicine sales outlet staffs were highly concerned about following the drug act and not dispensing antimicrobials without a prescription, and usually refer a patient to get a prescription from a doctor if the patient has complications (like high fever, generalized malaise, fatigue as symptoms, sinusitis). Stronger concerns were also observed for medicine outlet staff not dispensing antimicrobials without a prescription if the patient is pediatric or geriatric with a severe infection. They also evaluated patients and dispensed antimicrobials based on symptoms, not their age or gender. However, they tended not to dispense antibiotics if the patient had a mild fever and requested it without a prescription.

Conclusion
Our results provide insight into the need for a national surveillance system for monitoring antimicrobial prescribing and dispensing practices at medicine sales outlets. Therefore, the selection of antimicrobials for treating infectious diseases may be informed by evidence-based antimicrobial prescribing and dispensing surveillance data and will help policymakers to know the pattern of commonly consumed antimicrobials in the medicine sales outlets.
Validity and reliability of upper body push and pull tests to determine one-repetition maximum
Authors: Sigvaldsen Eirik , Loturco Irineu , Larsen Fredrik , Bruusgaard Jo , Kalhovde John Magne , Haugen Thomas 
Published: July 2023

ObjectivesThe purpose of this study was to explore the validity and reliability of three different strength testing approaches to determine one-repetition maximum (1RM) in the bench press and prone bench pull.MethodsTwenty-eight recreationally active subjects (25 ± 2 years, 178 ± 8 cm, 78 ± 9 kg) were assessed for load-velocity (L-V) relationship, 1RM, maximal isometric force (MIF), and maximal repetitions to failure (MRF) in a Smith Machine on three separated sessions. Linear regression was used for L-V relationship, MIF, and MRF to predict 1RM. Level of significance was set to ρ ≤ 0.05.ResultsReliability analyses of the varying 1RM estimations revealed mean differences from 0.6 to -1.3 kg (mainly trivial effects) between test days 1 and 2, intraclass correlation coefficient was > 0.96, and coefficient of variation (CV) was in the range 2.3–8.3% for all tests. Regarding validity, all 1RM predictions exhibited a mean difference ≤ 1.3 kg (trivial), except for the L-V relationship method that underestimated the predicted 1RM by 5 kg (small) compared to the actual bench press 1RM. However, the L-V relationship method showed the least mean absolute errors. CVs were in the range 4.5–13.2%. Standard error of the estimate was in the range 3.2–9.7 kg. Change scores for all tests were significantly correlated with change scores in actual 1RM, except for MIF in the prone bench pull. Smallest deviations in 1RM predictions were observed for the L-V relationship approach.ConclusionsAll 1RM prediction methods were highly comparable to the traditional 1RM test. However, given the high variability associated with individual predictions for each method, they cannot be used interchangeably.
The use of anakinra in a patient with gout and long-term follow-up of rheumatoid arthritis
Authors: Cheremushkina E. V. , Eliseev M. S. , Semashko A. S. , Alekseeva A. V. , Lila A. M. 
Published: July 2023

Gout is a chronic inflammatory arthropathy, caused by articular and periarticular sodium monourate (MUN) crystals deposition on the background of chronic hyperuricemia. Gout belongs to the group of autoinflammatory diseases characterized by activation of the innate immune system. In some cases, especially in women, with a long course of the disease and absence of adequate therapy, chronic arthritis is detected, which has little difference from that in rheumatoid arthritis (RA). At the same time, until recently, the combination of RA and gout was considered casuistry due to the inhibition of crystal formation by specific factors associated with RA, what is more mechanisms of inflammation development characteristic of these diseases are completely different. However, according to the latest data, the coexistence of these two diseases in one patient is possible, and the therapy of both, gout and RA (in some patients) can be successful when prescribing biological disease modifying antirheumatic drugs, in particular inhibitors of the interleukin 1 receptor (IL1r).The article presents a rare clinical case of chronic tophi gout in an elderly patient who was followed up for a long time with a diagnosis of RA, a significant improvement was achieved on therapy with the IL1r antagonist anakinra.
Environmentally friendly synthesis and computational studies of novel class of acridinedione integrated spirothiopyrrolizidines/indolizidines
Authors: Raju Rajesh , Raghunathan Raghavachary , Arumugam Natarajan , Almansour Abdulrahman I. , Kumar Raju Suresh , Vivekanand P. A. , Ebenezer Cheriyan , Solomon Rajadurai Vijay , Perumal Karthikeyan 
Published: July 2023

Abstract
An efficient and environmentally benign synthesis of a new class of acridinedione embedded spirooxindolo/acenaphthenothiopyrrolizidines and spirooxindolo/acenathenoindolizidines has been synthesized in good to excellent yields employing ionic liquid accelerated one-pot [3 + 2]-cycloaddition strategy. The pre-requisite starting substrates, O-acryloyl acridinediones were prepared from dimedone in three good yielding steps, while the 1,3-dipole was derived in situ from isatin/acenaphthenequinone and thiazolidine-4-carboxylc acid/l-pipecolinic acid via decarboxylative condensation. The cycloadduct possesses three stereogenic carbons, one of which is a spiro carbon through the formation of two C–C and one C–N bonds in one-pot synthetic transformation. Geometrical parameters of the synthesized compounds were calculated using the B3LYP/6-311g(d,p) level of theory. The activity of these molecules was evaluated against main protease of COVID-19 to screen them for their inhibitor efficiency. In order to get a broad understanding of the interactions of these synthesized ligands, a detailed molecular docking analysis was performed. Molecular docking analysis shows that compound 8b has the highest binding affinity toward the protein. The compound can be a potential candidate for the treatment of COVID-19.
Decommodifying Spanish-English bilingualism: aggrieved whiteness and the discursive contestation of language as human capital
Authors: Subtirelu Nicholas 
Published: July 2023

AbstractOver the past few decades in the United States, a powerful consensus has emerged around the value of bi-/multilingualism as human capital, including as an advantage for individuals on the labor market. In this article, I consider how the advantage that Spanish-English bilingualism affords some Latinxs on the labor market might be contested, especially by whites who feel disadvantaged by employers’ preferences for bilingual workers. I explore data from an online petition opposing the use of bilingualism in hiring decisions. Drawing on insights from critical discourse analysis, linguistic anthropology, and the sociology of race, I analyze the discursive strategies that petition signers use to contest the economic advantages afforded by Spanish-English bilingualism. I show that signatories draw on a set of strategies that includes reproducing a naturalized one nation, one language ideology; constructing English as equal opportunity language; decommodifying Spanish; and racializing Spanish and its speakers. My analysis suggests that the apparent economic advantages afforded by Spanish-English bilingualism are a salient target for white racial resentment. Thus, I argue that discussions centering around bi-/multilingualism as human capital should consider how neoliberalism and aggrieved whiteness both, in different ways, undermine the labor market advantages bilingualism offers some Latinxs.
Embryonic and fetal tiny pericardial fluid collections at less than 12 weeks of gestation
Authors: Hata Toshiyuki , Kawahara Tomomi , Miyake Takahito 
Published: July 2023

Abstract

Objectives
To describe embryonic and fetal tiny pericardial fluid collections (PFCs) using transvaginal sonography and HDlive Silhouette at less than 12 weeks of gestation.

Methods
During an 8-month period from November 2021 to June 2022, one-hundred and thirty transvaginal scans were performed for first-trimester dating, and eleven tiny PFCs of the embryo or fetus were identified at 8+4 – 11+3 weeks of gestation (three at 8, six at 9, and two at 11 weeks). HDlive Silhouette features of PFC were evaluated. Their clinical characteristics and outcomes were also investigated.

Results
The incidence of tiny PFCs was 8.5 % at less than 12 weeks of gestation. The mean gestational age at the initial examination was 9.5 weeks (SD: ± 0.9). The mean crown-rump length was 25.0 mm (SD: ± 8.5). The mean PFC dimension was 0.8 mm (range: 0.5–1.3, SD: ± 0.2). Pleural effusion was associated with 3 out of 11 PFCs (27.2 %). Ascites was noted in 2 cases (18.2 %). Skin edema was identified in only in 1 case (0.09 %). There was no arrhythmia. Tiny PFC could also be depicted using HDlive Silhouette. First-trimester fetal ultrasound scans at 11 – 13+6 weeks showed no abnormal findings. PFCs resolved until 13 weeks of gestation (Mean: 12 weeks, SD: ± 1.2). All PFC pregnancies resulted in healthy neonates.

Conclusions
The incidence of tiny PFCs was relatively high in early pregnancy. HDlive Silhouette can depict tiny PFCs of the embryo. Tiny PFCs in early gestation are transient, benign findings in utero.
Non-dispersive Fano resonances in hybrid plasmonic-distributed Bragg reflector structures
Authors: Wang Shuangshuang , Hu Huatian , Liu Xiaoze , Ding Tao 
Published: July 2023

Abstract
Fano resonance due to coupling of plasmon mode and Bragg modes is revealed without strong angular dependence based on Au nanoparticle on distributed Bragg reflectors (Au NPoDBRs). This Fano interference involves three-modes-coupling: the nanoparticle’s plasmon resonance, dispersive Bragg modes, and non-dispersive Bragg modes. It can be interpreted as a consequence of two processes: plasmonic coupling between dispersive Bragg modes and broad plasmon mode, and the strong coupling between narrowed plasmonic mode and non-dispersive Bragg mode. This Fano interference shows little dependence on the incidence angle but high tunability with the top-layer thickness, which is exploitable for novel nanophotonic devices with dispersion engineering.
Sind Subventionen für Halbleiter zu rechtfertigen?
Authors: Gropp Reint , Reifschneider Alexander 
Published: July 2023

Zusammenfassung
Reint Gropp und Alexander Reifschneider beleuchten in diesem Artikel die wichtigsten Argumente für und gegen die Subventionen, die im Rahmen des European Chips Acts für Halbleiter in Europa und in Deutschland geplant sind. Sie gehen dabei auch auf die geostrategischen Argumente ein. Es zeigt sich, dass die Subventionen für Produktionsanlagen für Halbleiter sehr schwer zu rechtfertigen sind. Subventionen für Forschung und Entwicklung statt für Produktion wären eine bessere Verwendung von Steuergeldern.