bluuebunny/crossref_metadata_2025_split huggingface dataset:
L’autonomie doctrinale des principes de justice : force ou faiblesse de la théorie rawlsienne ?
Authors: Audard Catherine 
Published: June 2023

La question de la cohérence de la théorie rawlsienne de la justice et de son tournant politique a été depuis longtemps une source de débats et de malentendus. Pour certains interprètes, l’abandon par le second Rawls d’un fondement kantien des principes de justice au profit d’un libéralisme purement politique serait un prix trop élevé à payer pour obtenir un large consensus sur des principes de justice dans des sociétés démocratiques traversées par des conflits de valeurs insurmontables. « La vérité dérangeante ( inconvenient truth ) que Rawls découvre est qu’il est impossible, écrit Robert Taylor (2011), de parvenir à un consensus par recoupement sur une conception kantienne de la personne ou plus largement sur la justice comme équité », mais qu’en même temps, sans un tel fondement, la force morale de la théorie de la justice serait diluée. Dans cet article, je voudrais répondre à ces critiques et montrer que, bien loin de conduire au relativisme, l’exigence d’autonomie doctrinale et d’indépendance des principes de justice à l’égard de toute conception substantielle du Bien exprimée par Rawls ( Libéralisme politique , p. 133) exprime le sens qu’a pour lui l’idéal démocratique : le respect pour l’autonomie morale des personnes et le rejet de « la pratique séculaire de l’intolérance comme condition nécessaire à l’ordre et à la stabilité de la société » ( Libéralisme politique , p. 14). Mais un tel idéal n’est-il pas irréaliste ? Faire ainsi confiance à l’autonomie des citoyens, à leur capacité à distinguer entre leurs doctrines morales personnelles et des principes publics de justice ( Libéralisme politique , p. 7) ne risque-t‑il pas d’affaiblir les démocraties au lieu de garantir leur stabilité, comme l’espère Rawls ( Libéralisme politique , p. 4) ? Cette ambition d’autonomie doctrinale est-elle une force ou une faiblesse de la théorie rawlsienne ?
Se déconnecter du travail : un droit en devenir ou une responsabilité collective ?
Authors: Rousseau Alexandre , Bertholet Jean-François 
Published: June 2023

Pouvoir commencer à travailler aux premières heures de la journée quand vous êtes en pleine forme pour finir plus tôt : vous ne voyez que des avantages au télétravail ! Or, si votre patron vous appelle un vendredi à 16 h 40 alors qu’il n’y a aucune urgence, vous répondez ou vous ne répondez pas ?
De la statue à la pierre selon José Saramago
Authors: Levécot Agnès 
Published: June 2023

José Saramago a affirmé en 1999, et répété plus d’une fois, que dans la première phase de sa production romanesque, il n’a fait que décrire des statues, restant à la superficie de la pierre. Puis, à partir de L’Aveuglement , explique-t-il, « j’ai perçu le nouveau monde qui se présentait à moi si j’abandonnais la superficie de la pierre pour en pénétrer l’intérieur ». Il s’agit ici de montrer comment se manifeste ce changement de perspective à partir de quelques exemples tirés de son œuvre romanesque et de discuter cette assertion.
Hors monde ?
Authors: Barbaras Renaud 
Published: June 2023

Le Hors phénomène consiste en ceci que ce n’est pas seulement l’horizon de l’existence qui se trouve bouché mais la possibilité même d’ouvrir un horizon qui est compromise. Il ne renvoie pas à une certaine apparition qui, aussi violente soit-elle, suppose toujours le champ de l’apparaître, mais bien à un ébranlement de la possibilité même d’apparaître : à une phénoménologie de la nuit, qui étend la phénoménalité jusqu’à l’inapparaissant ou au neutre, il faudrait opposer une nuit de la phénoménologie. La question qui se pose alors est la suivante : de cette nuit de la phénoménologie, y a-t-il encore une phénoménologie ou ne signifie-t-elle pas plutôt une sortie pure et simple de la phénoménologie ? En répondant par l’affirmative, en faisant une phénoménologie du Hors phénomène, ne court-on pas le risque d’ouvrir à nouveau l’horizon dont le Hors phénomène est la dénonciation en acte ?
L’extra-phénoménalité à l’épreuve de la solitude
Authors: Audi Paul 
Published: June 2023

Hors phénomène prétend à une « philosophie créatrice ». Or c’est bien ce pas, quasi nietzschéen, qu’accomplit Emmanuel Falque en distinguant l’ infra -phénoménal, le supra -phénoménal et l’ extra -phénoménal. Il développe une « philosophie pour temps de crise » et ouvre un champ essentiel pour la pensée aujourd’hui. On se demandera cependant si un tel déport hors de la phénoménalité n’avait pas déjà été au moins aperçu par Martin Heidegger, non pas dans le « retrait », mais dans le « recouvrement » et la « dissimulation » du phénomène. C’est en réalité avec la psychanalyse que l’auteur dialogue ici, quoique sans la citer souvent, y ayant déjà consacré un livre par ailleurs : « Ça » n’a rien à voir (Cerf, 2018). Les notions de « sidération » et de « refoulement » aideraient grandement à éclairer la notion de Hors phénomène. Et c’est surtout à Rousseau et aux Rêveries du promeneur solitaire qu’il faut revenir. Car loin d’être une simple « solitude privative », cette méditation rousseauiste décrit en propre ce que le dernier chapitre de Hors phénomène nomme la « solitude originelle ».
Hors phénomène et l’homme blessé
Authors: Philippart de Foy Olivier 
Published: June 2023

En quoi Hors phénomène peut-il nous aider à penser le handicap mental ? On y trouve l’essentiel, à savoir qu’on n’a d’autre choix que de se tenir « devant ce quoi on bute » les uns « à côté ou aux côtés » des autres. Toutefois pour parvenir à « “être-là” pour “vivre avec” », il ne suffit pas de se confronter au trauma du handicap mental car nous sommes aussi convoqués-attendus ailleurs. Si le handicap mental traumatise la personne qui le subit, cette personne à son tour traumatise ses proches. On découvre alors que toute situation traumatique comprend deux scènes traumatiques. Or, comme y insiste Emmanuel Falque, le pire est de ne pas parvenir à constituer « son noyau de solitude ». Comment faire pour rester présent à ceux qui éveillent en nous plus d’inquiétude que de joie et ne pas glisser de la solitude à l’esseulement ?
L’enfantement, un problème non théologique ?
Authors: Picard Clarisse 
Published: June 2023

À l’heure où les techniques reproductives sont sur le point de remplacer le corps et la subjectivité des femmes dans l’enfantement, il vaut la peine de s’interroger sur les enjeux anthropologiques, mais aussi téléologiques et théologiques de l’enfantement : en quoi l’enfantement, défini comme l’expérience d’incarnation de soi, d’une mère et de son enfant, serait-il un problème théologique ? La présente réflexion se propose de déployer cette question dans l’horizon du problème du rapport entre incarnation phénoménologique et Incarnation théologique, en empruntant le chemin d’une phénoménologie de l’enfantement, selon « la voie de la monadologie », l’une des voies par lesquelles la phénoménologie husserlienne tâche d’« atteindre Dieu sans Dieu ». Au terme de l’itinéraire, un sujet singulier devenant mère fait apparaître la source originaire constituante, le mouvement et le sens constitué de l’expérience phénoménologique de l’enfantement, ainsi que son rapport à l’ idée de Dieu chez Husserl.
Élaborer le cercle méridien Ertel & Sohn de l’Observatoire de Neuchâtel (1858-1861) : besoins scientifiques, possibilités techniques et contraintes financières
Authors: Gressot Julien , Jeanneret Romain 
Published: June 2023

Lors de la fondation d’un observatoire, le choix de l’instrumentation est d’une grande importance pour réaliser des observations scientifiques reconnues et s’insérer ainsi dans le réseau international d’institutions astronomiques. Durant le xixe siècle, le cercle méridien est l’instrument central de l’astronomie de position. Son acquisition par le nouvel Observatoire de Neuchâtel est donc un moment crucial pour une institution qui entend être à la pointe de la mesure du temps. À partir d’une riche correspondance entre un astronome et un fabricant, les enjeux entourant l’élaboration d’un cercle méridien tirant le parti d’innovations électrotechniques se donnent à voir. En considérant l’instrument comme un maillon d’un assemblage spécifique, une chaîne opératoire de la détermination de l’heure, nous allons approfondir la constitution d’un instrument scientifique de haute précision : le cercle méridien Ertel & Sohn de l’Observatoire de Neuchâtel.
Les lanternes publiques, exosquelette de la « machine » policière (Paris, xviiie siècle)
Authors: Bothereau Benjamin 
Published: June 2023

Que peut apporter l’histoire des techniques à la compréhension de la police moderne ? Cet article vise à montrer comment la généralisation de l’éclairage public parisien au xviiie siècle participe à la matérialisation de l’action policière dans la cité, en même temps qu’elle alimente la métaphore de la « machine » policière. Les lanternes, en éclairant de façon homogène et synchrone tout le territoire parisien, prennent non seulement part au nouveau style policier mais donnent véritablement « corps » à la jeune lieutenance de police parisienne.
Seven-year microbiological profile and antibiotic sensitivity pattern of burn wound infections in a tertiary care hospital in New Delhi
Authors: Singh Vikas , Grover Naveen , Tandel Kundan , Jena Salil 
Published: June 2023

Introduction:
Burn patients are vulnerable for opportunistic colonization by organisms of endogenous and exogenous origin. Hence, it is necessary to evaluate the flora obtained from wounds of burn patients to determine the most effective treatment. The aim of this study was to determine the incidence of various bacteria isolated from burn patients and to determine their antimicrobial susceptibility and resistance pattern spanning 7 years.

Materials and Methods:
The retrospective study included all the culture reports obtained over a period of 7 years (2012–2018).

Results:
Out of the total 1474 positive samples analyzed, the most common sample reported was pus (n = 816), followed by blood culture (n = 314), tissue (n = 188), and urine (n = 156). The most common organism cultured was Pseudomonas aeruginosa (n = 377), followed by Klebsiella pneumoniae (n = 309). Other commonly isolated organisms were Acinetobacter baumannii (n = 206), Escherichia coli (n = 89), coagulase-negative staphylococci (n = 88), Proteus mirabilis (n = 55), Burkholderia cepacia (n = 54),Staphylococcus aureus (n = 42), Candida spp. (n = 39), and Enterococci spp. (n = 36). Pseudomonas was seen to be sensitive to only colistin with resistance to all other major antibiotic classes. Klebsiella was sensitive to colistin, tigecycline, and cefoperazone/sulbactam. A. baumannii was observed to be sensitive only to colistin and tigecycline by the end of 2018 andE. coli was sensitive to amikacin, colistin, meropenem, and tigecycline.

Conclusion:
Antibiotic resistance is rampant, rapidly progressing and devouring down all the antibiotic classes one after other. The high antimicrobial resistance may be ascribed to the inappropriate use of broad-spectrum antibiotics and lack of a definite antibiotic policy in hospitals. Treating surgeons should frequently evaluate the burn patient and run regular tests to localize the most common organisms causing the infections with their antibiotic sensitivity profiles.
Postburn neck contracture reconstruction by interval skin grafting
Authors: Ahmad Imran , Karad Somnath , Khurram Mohammed Fahud , Ali Sheikh Sarfraz , Tripathi Sudhanshu , Chaudhury Gautam 
Published: June 2023

Introduction:
Delayed burn wound healing, due to lack of proper initial treatment, especially in deep partial-thickness and full-thickness burns leads to the formation of burn scar contracture. Because of the loose tissue in the anterior neck and also due to habitual and ignorant use of a pillow in burnt patients during the postburn recovery phase, contracture of the neck is a common sequela. Many reconstructive modalities have been described in the literature which include skin grafting, pedicle flap with or without expansion, and free flap. Keeping the esthetic concern in mind, we modified the method of contracture release and skin grafting into two stages.

Materials and Methods:
This is a prospective study conducted on 15 patients with extensive postburn contracture of the neck during the period ranging from January 2020 to August 2021.

Results:
In our study, 80% of the patients were females. The mean age was 25.9 years. The number of type 2 and type 3 neck contractures was 7 and 8, respectively. The mean duration of contracture was 8.26 months. Graft loss was the only complication seen and that too was < 10% in all cases (mean - 4.46). At 6 months, mandibular border and thyroid bulge were distinctly visible, and cervicomental angle was within the normal range (mean - 110.46) giving a youthful and appealing esthetic appearance. The mean of the Patient and Observer Scar Assessment Scale score was 2.06 for the observer component and 3 for the patient component.

Conclusion:
Interval skin grafting can be undertaken following postburn neck contracture release for better functional and esthetic outcomes.
Epidemiology of severe scald in 0–5–year-old children at the Department of Plastic and Reconstructive Surgery, Gauhati Medical College and Hospital – A 5-year retrospective study
Authors: Baishya Jyotirmay , Nithin M. , Boruah Poresh , Kalita Kabita 
Published: June 2023

Background:
The 0–5-year-old age group has the highest incidence of scalds. In assessing a child with scalds, it will be beneficial to look at the interactions between the host, substance, mechanism, and environment. These factors have an effect on the degree, percentage, distribution, and pattern of injury sustained by the child.

Subjects and Methods:
This retrospective study comprised children aged 0–5 years who were admitted to the Burn Unit of the GMCH, Guwahati, with scald wounds between January 1, 2017, and December 31, 2021, for a period of 5 years. After receiving ethical committee approval, the records of the patients were gathered from the medical records department of GMCH, Guwahati, during this time period.

Results:
Majority of the incidences were found in male children aged 9–12 months. Scalds commonly occur in rural areas and indoor at home. The upper lower class had the most scald injuries and parents had a poor educational status. The most common substance was hot water in a vessel. The most common mechanism was for a child to pull a hot water down over themselves. In descending order, children suffered a significantly higher proportion of scalds to the hand, chest, and face.

Conclusions:
Children should be closely supervised by elders or parents, particularly in the kitchen while at home. Parents and caregivers should receive preventive education and training. All kitchen practices, such as floor cooking, low-level shelves, and keeping hot liquids in easily accessible places, should be avoided to prevent childhood scalds.
Educational Needs of Persons with Epilepsy
Authors: Ghosh Rinki , Arunjyoti Baruah 
Published: June 2023

Background:
Epilepsy is a devastating global health concern and can develop at any time in one's life. Inadequate knowledge and awareness about the disease and its causation, discrimination, social stigma are the most prevalent factors which often dissuade persons with epilepsy from seeking treatment.

Methods:
The study used descriptive qualitative research design and semi-structured interview to explore the educational needs of persons with epilepsy. Non-probability purposive sampling technique was used for selection of study sample based on study eligibility criteria. Data saturation was achieved after interviewing 8 samples. Thematic analysis was performed for analysis of the data. Statements were coded and different codes were collated into categories and subsequently into themes. Rigor and quality of the data was ensured using measures of credibility, transferability, dependability and conformability.

Results:
Three major themes namely exiguous knowledge, Deviant epilepsy management and Pragmatic challenges emerged from the analysis. The study finding revealed poor knowledge and awareness and inadequate skill in epilepsy self-management amidst many challenges among majority of the study participants.

Conclusion:
Therefore, there is a need to educate people with epilepsy about the disease and its self-management to manage their epilepsy well and enhance their quality of life.
Effectiveness of Problem-Based Learning versus Traditional Lecture Method in Terms of Knowledge among Nursing Students in a Selected Nursing College of Kashmir
Authors: Amin Ishrat , Tamang Eke Lama , Khan Mikki 
Published: June 2023

Introduction:
The rapid advancement in medical technology and science demands nursing education to become hybrid, combining traditional teaching methods with modern methodologies. Problem-based learning (PBL) is one of the new methods, which facilitates student's learning.

Objective:
The study aimed to assess and compare the nursing students' knowledge regarding myocardial infarction taught by PBL and traditional lecture method.

Methods:
A quantitative research approach with post-test-only research design was used. All 50 B.Sc. 2nd-year nursing students were included in the study. A structured knowledge questionnaire was used to assess the knowledge.

Results:
The findings revealed that the mean knowledge score of nursing students in the PBL group was 24.28 and in the traditional lecture group was 19.36. The obtained mean difference between PBL group and traditional lecture group was found to be statistically significant as evident from 't' = 2.71 at 0.05 level of significance. The study findings also revealed that in the PBL group, 16% of nursing students had acquired poor knowledge, 68% had acquired average knowledge and 16% had acquired good knowledge, whereas in the traditional lecture group, 40% of students had acquired poor knowledge, 52% had acquired average knowledge and 8% had acquired good knowledge.

Conclusion:
The study revealed that the mean knowledge score after post-test of nursing students in the PBL group was higher than mean knowledge score after post-test of nursing students in the traditional lecture group; hence, PBL method was more effective than traditional lecture method.
Development and Initial Evaluation of Informal Caregiver Burnout Scale
Authors: Tamarana Rameshbabu , Jain Esha , Sinha Snigdha , Manjunatha Surabhi , Amissah Awurakua Amaki , Balaji Bhavna 
Published: June 2023

Background:
Individuals in service-oriented professions, such as caregivers, often face burnout. Informal caregivers, in particular, are individuals who care for another individual/s for no monetary benefit and do not necessarily require professional training for the same.

Objectives:
The study aimed to quantify informal caregiver burnout in the form of a scale, for which the domains of three main variables concerning the tridimensional characterization of the burnout syndrome included emotional exhaustion, cynicism and professional efficacy. In addition, the scale focused mainly in primary appraisal (how the caregiver evaluates their condition) rather than secondary appraisal (coping with stressful situations). The current study evaluated the psychometric properties of the informal caregiver burnout scale (ICBS) to assess burnout levels amongst informal caregivers.

Results:
Results from exploratory factor analysis provide preliminary psychometric support for dimensionality and reliability and suggest further revisions to future versions of the scale. Importantly, dimensionality findings from the current study found two dimensions.

Conclusion:
Further, replications using a more targeted sample of participants should improve dimensionality findings.
Indole curcumin combats metastatic HBV-positive hepatocellular carcinoma by inhibiting cell proliferation, migration, and matrix metalloproteinase-9 activity
Authors: Subramanian Srividya , Pajaniradje Sankar , Tumdam Roshan , Hoda Mudassarul , Dasgupta Asmita , Rajagopalan Rukkumani 
Published: June 2023

ABSTRACT

Background:
Chemical modification of the natural products and molecules can lead us toward drugs with lesser off-target effects for chemotherapeutic use against cancers. In this study, we explored the effect of an indole analog of the molecule curcumin, for the first time against HBV-positive hepatocellular carcinoma (HCC) cells in vitro.

Materials and Methods:
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and lactate dehydrogenase assays were used to measure the cytotoxic effects of indole curcumin against Hep3B cells. The mode of cell death was established through acridine orange/ethidium bromide fluorescence staining, propidium iodide fluorescence staining, and the comet assay. The effect of the compound on cell migration behavior was studied through wound healing assay, whereas the effect on matrix metalloproteinase (MMP) activity was evaluated using gelatin zymography. In silico molecular docking was performed to predict the affinity of indole curcumin toward probable intracellular interacting partners.

Results and Discussion:
Indole curcumin had an antiproliferative effect on Hep3B cells, induced apoptotic mode of cell death, inhibited cell migration in time- and dose-dependent assays, and decreased MMP-9 activity levels. Molecular docking results suggest that the interaction of PI3K with indole curcumin may have led to downregulation of MMP-9 expression, thereby contributing to the overall reduction in MMP-9 activity.

Conclusion:
Our study establishes that indole curcumin is an effective cytotoxic and antimetastatic agent against hepatitis virus-B positive HCC cells. Hence, it can be a possible candidate for the treatment of hepatocarcinoma induced/promoted by the presence of chronic hepatitis B infection.
Recurrent dermatofibrosarcoma protuberans: A report of two cases involving the trunk and abdominal wall
Authors: Vindal Anubhav , Lal Tusharindra , Gupta Yashika , Kale Ashish Rasik , Lal Pawanindra 
Published: June 2023

ABSTRACT
In this paper, we report two cases of dermatofibrosarcoma protuberans (DFSP) who were treated with distinct surgical approaches. In the first case, a 50-year-old woman presented with a mass on her right shoulder and underwent local excision with subsequent reconstruction using a deltopectoral flap. The second case was of a young female who presented with a giant protuberant DFSP on the anterior abdominal wall who was treated with wide local excision along with inlay mesh repair of the defect. Early excision and adjuvant radiotherapy facilitates a low recurrence rate while also improving the prognosis of the patients.
Is FGFR4 Gly388Arg missense variant a suitable prognostic marker in neuroblastoma?
Authors: Katarzyna Szewczyk 
Published: June 2023

ABSTRACT

Context:
Evidence suggested that FGFR4-Arg388 allele is frequently detected in multiple cancers with rapid progression and unfavorable clinical implications.

Aims:
It was investigated whether the FGFR4 missense variant (Gly388Arg) could serve as a prognostic biomarker and therapeutic target in neuroblastoma (NB).

Materials and Methods:
FGFR4 genotypes were determined by DNA sequencing in 34 NB tumors. The results were correlated with patient outcomes and prognostic features.

Results:
The frequency of the pathogenic allele in NB tumor tissue was 47% (35.3% Gly388Arg and 23.5% Arg388Arg), which was higher than that reported in a previous study from peripheral blood. Missense variant FGFR4-Arg388 was more popular in localized tumors withouth MYCN gene amplification.

Conclusions:
We investigated, for the first time, the frequency of the FGFR4-Arg388 missense variant in NB tumors. The different distribution of the pathogenic allele was presented in different biological groups, especially with and without MYCN copy number enhancing, as well as in patients with various clinical features.