bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predicting ion mobility collision cross sections using projection approximation with ROSIE-PARCS webserver
Authors: Turzo S M Bargeen Alam , Seffernick Justin T , Lyskov Sergey , Lindert Steffen 
Published: August 2023

Abstract
Ion mobility coupled to mass spectrometry informs on the shape and size of protein structures in the form of a collision cross section (CCSIM). Although there are several computational methods for predicting CCSIM based on protein structures, including our previously developed projection approximation using rough circular shapes (PARCS), the process usually requires prior experience with the command-line interface. To overcome this challenge, here we present a web application on the Rosetta Online Server that Includes Everyone (ROSIE) webserver to predict CCSIM from protein structure using projection approximation with PARCS. In this web interface, the user is only required to provide one or more PDB files as input. Results from our case studies suggest that CCSIM predictions (with ROSIE-PARCS) are highly accurate with an average error of 6.12%. Furthermore, the absolute difference between CCSIM and CCSPARCS can help in distinguishing accurate from inaccurate AlphaFold2 protein structure predictions. ROSIE-PARCS is designed with a user-friendly interface, is available publicly and is free to use. The ROSIE-PARCS web interface is supported by all major web browsers and can be accessed via this link (https://rosie.graylab.jhu.edu).
Decomposing Neighbourhood (In)Stability: The Structural Determinants of Turnover and Implications for Neighbourhood Crime
Authors: Williams Seth A 
Published: August 2023

Abstract
While the human ecological model views neighbourhood instability as a function of household-level decisions, the present study draws on a political economy of place perspective to highlight how the profit-seeking interests of outside actors shapes instability, with consequences for neighbourhood crime. Using data on neighbourhoods in Los Angeles County from 2007 to 2013, I decompose levels of stability according to housing dynamics (displacement, development, changing rents, sales, low-income units), and assess their direct and indirect association with violent and property crime. I find that, over a 7-year period, poorer neighbourhoods are more vulnerable to these exchange-value pressures, stability is more consequential to crime in high-poverty neighbourhoods, and certain housing dynamics are associated with increasing crime through their detrimental effect on renter stability.
Understanding Perceptions of Victimization: A Critical Analysis of Gay and Bisexual Male Grindr Users Negotiations of Safety and Risk
Authors: Colliver Ben 
Published: August 2023

Abstract
The victimization of gay and bisexual men has gained significant academic and social attention, with that focus extending to the role of digital victimization. Grindr has dominated the market for online dating apps targeting gay, bisexual, trans and queer people. Drawing on qualitative data collected from men who use Grindr, this paper addresses a gap in criminological literature by exploring the way that men that have sex with men negotiate perceptions of safety when engaging in real-world meetings that have been facilitated by Grindr. It is argued throughout this paper that risk-reduction strategies adopted by interviewees only reduce the perception of risk, rather than the actual risk of experiencing violent victimization. As such, it is claimed exploring digital integration offers a more nuanced reading of the intertwined and fraught relations of risk and safety within digital and physical spaces.
In-stent restenosis after percutaneous coronary intervention: emerging knowledge on biological pathways
Authors: Pelliccia Francesco , Zimarino Marco , Niccoli Giampaolo , Morrone Doralisa , De Luca Giuseppe , Miraldi Fabio , De Caterina Raffaele 
Published: August 2023

Abstract
Percutaneous coronary intervention (PCI) has evolved significantly over the past four decades. Since its inception, in-stent restenosis (ISR)—the progressive reduction in vessel lumen diameter after PCI—has emerged as the main complication of the procedure. Although the incidence of ISR has reduced from 30% at 6 months with bare-metal stents to 7% at 4 years with drug-eluting stents (DESs), its occurrence is relevant in absolute terms because of the dimensions of the population treated with PCI. The aim of this review is to summarize the emerging understanding of the biological pathways that underlie ISR. In-stent restenosis is associated with several factors, including patient-related, genetic, anatomic, stent, lesion, and procedural characteristics. Regardless of associated factors, there are common pathophysiological pathways involving molecular phenomena triggered by the mechanical trauma caused by PCI. Such biological pathways are responses to the denudation of the intima during balloon angioplasty and involve inflammation, hypersensitivity reactions, and stem cell mobilization particularly of endothelial progenitor cells (EPCs). The results of these processes are either vessel wall healing or neointimal hyperplasia and/or neo-atherosclerosis. Unravelling the key molecular and signal pathways involved in ISR is crucial to identify appropriate therapeutic strategies aimed at abolishing the ‘Achille’s heel’ of PCI. In this regard, we discuss novel approaches to prevent DES restenosis. Indeed, available evidence suggests that EPC-capturing stents promote rapid stent re-endothelization, which, in turn, has the potential to decrease the risk of stent thrombosis and allow the use of a shorter-duration dual antiplatelet therapy.
Prevalence of sufficient physical activity among general adult population and sub-populations with chronic conditions or disability in the USA
Authors: Xu Lijun , Li Tianshu , He Wenqi , Cao Dong , Wu Chenkai , Qin Lijie 
Published: August 2023

Abstract

Background
Recently, the World Health Organization (WHO) released an updated global guideline on physical activity and sedentary behavior, including recommendations for sub-populations living with chronic conditions or disabilities. We aimed to examine the prevalence of meeting the WHO recommendations among these sub-populations in the USA.

Methods
We conducted a cross-sectional study using data from the 2017 to 2018 cycle of the National Health and Nutrition Examination Survey (NHANES).

Results
We revealed variations in physical activity levels among individuals with chronic conditions and disability. US adults with diabetes, hypertension or disability had a lower prevalence of recommended physical activity levels than the general population. In addition, certain demographic groups such as being female, older and having lower socioeconomic status were associated with a lower likelihood of meeting the WHO recommendations on physical activity.

Conclusions
Our findings underscore the importance of promoting physical activity levels among US adults, especially those with older age, low socioeconomic status, hypertension and disability.
Introducing the International Treaty Ratification Votes Database
Authors: Ostermann Falk , Wagner Wolfgang 
Published: August 2023

AbstractThis research note introduces the International Treaty Ratification Votes Database, which covers more than 6,000 votes on the ratification of international treaties in Canada, Finland, France, Germany, Italy, Slovakia, Spain, Turkey, the United Kingdom, and the United States between 1990 and 2019. In addition, the database presents data on the voting behavior of ninety parties in eight of these countries, resulting in more than 11,000 party observations. The research note presents the two datasets with their two units of analysis, the parliamentary and the party level, and describes the main variables, reaching from descriptive vote and cabinet data to issue areas, comparative party family classifications, and actual voting records. Furthermore, we suggest avenues for using the data for future research on the domestic politics of foreign policy: Our data can be used to study patterns in the politicization of international treaties and organizations, ratification delays, legislative–executive relations, the party politics of foreign policy making, and the crisis of the liberal international order.
Apoptotic Factors Are Evolutionarily Conserved Since Mitochondrial Domestication
Authors: Kaushal Vandana , Klim Joanna , Skoneczna Adrianna , Kurlandzka Anna , Enkhbaatar Tuguldur , Kaczanowski Szymon , Zielenkiewicz Urszula 
Published: August 2023

Abstract
The mechanisms initiating apoptotic programmed cell death in diverse eukaryotes are very similar. Basically, the mitochondrial permeability transition activates apoptotic proteases, DNases, and flavoproteins such as apoptosis-inducing factors (AIFs). According to the hypothesis of the endosymbiotic origin of apoptosis, these mechanisms evolved during mitochondrial domestication. Various phylogenetic analyses, including ours, have suggested that apoptotic factors were eubacterial protomitochondrial toxins used for killing protoeukaryotic hosts. Here, we tested whether the function of yeast Saccharomyces cerevisiae apoptotic proteases (metacaspases Mca1 and Nma111), DNase Nuc1, and flavoprotein Ndi1 can be substituted with orthologs from remotely related eukaryotes such as plants, protists, and eubacteria. We found that orthologs of remotely related eukaryotic and even eubacterial proteins can initiate apoptosis in yeast when triggered by chemical stresses. This observation suggests that apoptotic mechanisms have been maintained since mitochondrial domestication, which occurred approximately 1,800 Mya. Additionally, it supports the hypothesis that some of these apoptotic factors could be modified eubacterial toxins.
Pouch Body Anastomotic Ulcerations Are Not Associated With an Increased Risk of Pouchitis
Authors: Hossain Marouf , Plietz Michael , Khaitov Sergey , Sylla Patricia , Greenstein Alexander , Dubinsky Marla C , Kayal Maia 
Published: August 2023

Lay Summary
Patients with isolated pouch body anastomotic ulcers may present with clinically significant symptoms such as increased stool frequency and hematochezia. Isolated pouch body anastomotic ulcers do not increase the risk of future pouchitis.
Contesting State Monologues: Indigenous Grassroots’ Struggles with Prior Consultation Norms in the Peruvian Amazon
Authors: Flemmer Riccarda 
Published: August 2023

AbstractPrior consultation (PC) has been an internationally enshrined norm for indigenous peoples’ rights since the 1980s. Indigenous peoples have called for PC for decades, but when governments finally begin implementation, a paradox results: previous advocates increasingly turn away from consultation processes. I argue that only with the perspective that norms are and should be contested “on the ground,” we are able to understand this contradiction. Therefore, the article presents a new conceptual and methodological interpretive framework for studying indigenous grassroots contestation. Drawing on ethnographic fieldwork in the Peruvian Amazon (2013–2016), I hone in on three layers of contestation—explicit contestation, attitudes and perceptions, and political implications—and demonstrate that (1) non-contestation confirms state monologues and is an alarming sign for silenced voices, not for norm support; (2) contested consultations reproduce asymmetries within indigenous groups replicating negotiations about extractive industry projects; and (3) opposition to consultation may be the most powerful tool for indigenous peoples to change narrow state interpretations and make use of veto rights. Scaling up these insights, the structure of PC accommodates two irreconcilable understandings: PC is either interpreted as an end in itself or as a means of indigenous self-determination.
Ukraine, Fostering Resilience, and the Importance of Preparedness
Authors: Runciman Brian 
Published: August 2023

Abstract
Over a year into the war in Ukraine, BCS spoke to experts from IT Ukraine Association and the UK about what we have learned about IT resilience, what Ukraine is still able to offer, and the implications for the role of IT technology in society. The webinar was chaired by Brian Runciman MBCS, BCS' Head of Content and Insight.
Comparison of Hb A1c Quantification in the Presence of Hemoglobin Variants of an HPLC Assay with an Enzymatic Assay
Authors: Nichols James H , Berman Marvin , Carrillo Alex , Manning Suzanne 
Published: August 2023

Abstract

Background
In this study, we evaluated the impact of hemoglobin (Hb) variants on the performance of the Abbott Alinity c and Bio-Rad Variant II Turbo 2.0 HPLC Hb A1c assays.

Methods
The analytical performance of the Abbott Alinity c Hb A1c (enzymatic) assay was compared to the Bio-Rad Variant II Turbo 2.0 HPLC method using leftover whole blood EDTA samples with and without the presence of a hemoglobin variant. Assay precision was determined from an analysis of controls. Bias was estimated from analysis of a set of 40 samples analyzed by a Tosoh G8 HPLC instrument at the University of Missouri Diabetes Diagnostic Laboratory, an NGSP Secondary Reference Laboratory.

Results
Between-day precision was excellent for both methods (&lt;3%). Bias met NGSP criteria of ±5% to target value. Correlation between the Alinity and Bio-Rad methods was good for patient samples without a hemoglobinopathy (y = 1.028x – 0.38, standard error of the estimate (SEE) = 0.16, n = 36, mean bias = −0.22). A total of 700 hemoglobin variant samples were evaluated on the 2 methods. Of the hemoglobin variants, 640/700 gave results on both methods: hemoglobin (Hb) S trait (n = 452), C trait (n = 131), D trait (n = 23), E trait (n = 26), and a mixture of other hemoglobinopathies (n = 8) including beta thalassemia, high hemoglobin F, transfused Hb SC, transfused Hb SD, and transfused Hb SS, or unknown variant. There was good agreement for the 640 Hb variants between the methods with a range of mean differences of −0.10 to +0.06 depending on the variant, but more variability (SEE 0.25 to 0.39). Sixty samples did not have paired results.

Conclusions
To our knowledge, this study was the largest investigation of the effect of hemoglobinopathies on the Abbott Alinity c Hb A1c assay. Analytical performance varied depending on the specific hemoglobin variant trait when compared to the Bio-Rad Variant II Turbo 2.0 HPLC method.
Communication about sensors and communication through sensors: localizing the Internet of Things in rural communities
Authors: Butkowski Chelsea , Chan Ngai Keung , Berniker Talia , Rodriguez Alfredo , Schlather Kenneth , Max Zhang K , Humphreys Lee 
Published: August 2023

AbstractInternet of Things (IoT) sensor networks are an emerging technology at the center of the datafication and optimization of far-reaching environmental infrastructures—from “smart cities” to workplace efficiencies. However, this low-power, low-cost technology is also well suited to local deployments in rural communities, which are often overlooked by digital development initiatives. Therefore, we used a social construction of technology approach to study how various U.S.-based IoT stakeholders—including designers and advocates as well as citizen stakeholders—understand and value sensor network technologies. Through observational methods, in-depth interviews, and participatory design research in a rural Upstate New York municipality, we worked to design sensor networks with rural community members to generate data about and for community members to further local knowledge. We found that designing rural sensor networks requires stakeholders to navigate obstacles of communication about sensors and communication through sensors to facilitate secure, ethical, and localized sensing in rural communities.
Negotiating the capacities and limitations of sensor-mediated care in the home
Authors: Hine Christine , Nilforooshan Ramin , Barnaghi Payam 
Published: August 2023

Abstract
In-home sensor systems supported by machine learning are increasingly used to enhance communication between those living with long-term conditions such as dementia and healthcare professionals and carers who support them. Perspectives from the sociology of infrastructures are used to explore the development and deployment of such a system of smart care, drawing on interviews with researchers and developers, healthcare professionals and service users, and carers. The analysis finds that labor of various forms is required to manage the production of useful sensor data, including parsing the reasons for missing data and organizing appropriate actions in response. The analysis highlights active processes of deriving meaning from that data in ways that participants find useful, ethical, and sustainable. The conclusion emphasizes the usefulness of an infrastructural approach in order to recognize the heterogeneous forms of labor involved in developing ethically sensitive, person-centered forms of remote-monitoring-enabled care.
Sensor work: enabling the interoperation of autonomous vehicles
Authors: Hind Sam 
Published: August 2023

Abstract
This article examines the “sensor work” carried out in the development of autonomous vehicles which, without sensor data, would not and arguably still do not, have the capacity to decide on where, and how, to drive. I begin by discussing three aspects of sensor technologies considered to be the foundation for sensor work being carried out in autonomous vehicle settings, namely the distribution, processing, and sourcing of sensor technologies and sensor data. The article considers how that much of this sensor work aids not only the operation of autonomous vehicles but also their necessary “interoperation.” In studying four specific sensing methods from an operational perspective, I consider how the interoperation between sensing devices and subsequent algorithmic, object-recognition, and motion planning procedures is fundamental to the development of autonomous vehicles.
Digital governance with smart sensors: exploring grid administration in Zhejiang’s “Future Community”
Authors: Zhao Yuchao 
Published: August 2023

Abstract
This study explored sensor-based e-government practices in eight pilot “Future Communities” in Zhejiang Province, China. Adopting the approach of “e-government in everyday practice,” it examines how grid members at the grassroots level make sense of smart sensors and their mediated governance through the parameters of passive response, collaborative human and nonhuman networks, and calculability. In an emerging sensing environment, grid members are exposed to contradictory governance regimes, experimenting with and performing competing sets of discourses and actions that are either efficient or inefficient, manual or automatic, and progressive or regressive. Neither facilitated nor emptied by sensor-enabled Weberian functions, they actively improvise along with the dynamism of specific local interactions and situations. However, currently sensors and attendant technologies merely leave space for them to engage in ambiguities and negotiations concerning the extent and boundaries of technical solutionism rather than opening up possibilities for empowerment to refine the forms of governance.
Framing Climate Litigation in Individual Communications of the African Human Rights System: Claw-Backs and Substantive Divergences
Authors: Jegede Ademola Oluborode 
Published: August 2023

Abstract
Climate litigation is anticipated to continue expanding, especially related to the interface with the human rights of vulnerable populations and the adequacy of states’ efforts to adopt and implement climate laws. While the possibility of climate-related litigation is envisaged before the African Human Rights System (AHRS), there is no pioneering case on climate change at that level yet. Essential rights that may be relevant in climate change litigation in the AHRS are not yet tested and often have claw-back clauses that have limits imposed by national legislation. Also, climate change commitments that may link to human rights are under a regime outside the AHRS. These developments may generate conceptual divergences regarding a state’s sovereign right and climate justice in future climate litigation within the AHRS. This article explores the potential application of claw-back clauses and divergent views on states’ sovereign rights and climate justice in climate change instruments that may feature in individual communications at the AHRS.
Decolonizing higher education: the university in the new age of Empire
Authors: Enslin Penny , Hedge Nicki 
Published: August 2023

Abstract
Campaigns to decolonize higher education have focused mainly on decolonizing the curriculum. Although the cultural features of colonialism and its material imperatives and damage were both modes of colonial domination and exploitation, more attention has been paid to the former in recent debates about education, and it tends to dominate arguments about and characterizations of decolonization in higher education, by making knowledge and the curriculum the central focus. We argue the need to attend not only to the cultural consequences of imperialism and the damage to the self so thoroughly emphasized in postcolonial and decolonial theory, but also to the material implications of colonialism and the evolution of Empire, which has persisted in new forms since formal decolonization. Decolonizing higher education and its institutions must also address new forms of Empire which have colonized the university. We argue that unless the material aspects of colonization and decolonization are adequately addressed, the university will not be substantively decolonized. Indeed, so strong is the influence of late capitalism in the form of neoliberalism on the contemporary university that its modes of practice are likely to foster superficial strategies to ‘decolonize’ the curriculum instead of addressing how capitalist structures and practices sustain current forms of coloniality. We discuss how neoliberalism, exemplified in the use of global rankings, shapes the contemporary university in today’s new age of Empire and we defend an approach to decolonizing that widens the focus of current debates beyond decolonization of the curriculum, to which we give qualified support.