bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Impact of Sleep Quality on Cognitive Function in Community-Dwelling Older Adults
Authors: Betyar Mahjoobeh , Kheirkhah Farzan , Hosseini Seyed Reza , Bijani Ali , Moudi Sussan 
Published: July 2023

Introduction: Given the high prevalence of poor sleep quality in late adulthood, older adults might be involved with different physical, mental and social consequences of this disorder. Current research was conducted to examine the association between sleep quality and cognitive function in community-dwelling older adults.

Methods: This cross-sectional study was carried out on 800 community-dwelling people aged ≥ 60 years living in Amirkola, North of Iran. The participants were selected by simple random sampling method. Mini-Mental State Examination, and the Pittsburgh Sleep Quality Index (PSQI) were used for data collection. Seven components of the sleep quality were categorized into the four groups (very good, relatively good, relatively poor, and very poor condition). The participants were divided into the two groups based on their cognitive function, and sleep quality was compared between these two groups. Mann-Whitney, Spearman's correlation analysis, Chi-square, Pearson's correlation test and Logistic regression analysis were used to analyze the collected data.

Results: Mean PSQI score among the older adults with normal and abnormal cognitive function was 5.5 ± 3.2 and 5.8 ± 3.3, respectively (p = 0.508). Poor sleep quality was slightly more prevalent in the elderly with cognitive dysfunction (p = 0.775). Logistic regression analysis revealed age (adjusted OR = 1.06; 95% CI: 1.03-1.08; p < 0.001) and level of education (adjusted OR = 0.14; 95% CI: 0.09-0.20; p < 0.001) had a significant impact on cognitive function; PSQI score (p = 0.254), gender (p = 0.661), and administration of sleeping drugs showed no significant effect (p = 0.081).

Conclusion: Among different components of sleep quality, a significant positive association was observed between the frequency of sleep disturbances with cognitive function in older adults; furthermore, older age and lower level of education showed a significant negative effect on cognitive function.
The Effect of Dynamic Neuromuscular Stabilization Exercises on Balance and Fear of Falling in Female Elderly
Authors: Mohseni Gazizeh , Nasab Firouzjah Ebrahim Mohammad Ali 
Published: July 2023

Introduction: The present study was an attempt to investigate the effect of a course of dynamic neuromuscular stabilization (DNS) exercises on balance and fear of falling in female elderly with a history of falling.

Methods: In this quasi-experimental study, 30 female elderly people with a history of falling based on entry and exit criteria were purposefully selected as a sample of study. Then, they were randomly assigned into two control and exercise groups. The variables related to static balance and dynamic balances were assessed by sharpened Romberg Test and Standing Up and Walking Test, respectively. Also, Falls Efficacy Scale International was used to measure the fear of falling. The exercise group performed DNS exercises for 8 weeks, 3 sessions, and 50 minutes per session. Data were analyzed by using paired t-test and analysis of covariance in SPSS24 software at the significant level of p < 0.05.

Results: A significant difference between pretest and posttest in static balance with open eyes (p = 0.0001, t = -7.19), static balance with closed eyes (p = 0.0001, t = -8.02), dynamic balance (p = 0.0001, t = 6.49) and fear of falling (p = 0.0001, t = 7.29) in DNS exercise group. Also, there were significant differences between DNS and control groups in static balance with open eyes (p = 0.0001, F = -14.67), static balance with closed eyes (p = 0.0001, F = 14.002), dynamic balance (p = 0.0001, F = 20.12) and fear of falling (p = 0.006, F = 09.07).

Conclusion: It is recommended that therapists use dynamic neuromuscular stabilization exercises in female elderly to improve balance and reduce the fear of falling.
The Role of Errors based on the Complexity in Learning a Motor Sequential Task in Elderly Women
Authors: Askarinejad Faeghe , Samadi Hossein , Ayatizadeh Tafti Farahnaz 
Published: July 2023

Introduction: One of the most important topics in the field of movement behavior is the acquisition of movement sequences, which is an important part of every person's life and the basis of many intelligent human behaviors. The aim of the study was to investigate the effectiveness of errorfull and errorless training based on complexity in the acquisition, retention and transfer of a motor sequential task in elderly women with emphasis on processing needs.

Methods: This semi-experimental study was conducted on 30 healthy elderly women over 60 years of age that were selected and randomly allocated into errorless and errorful groups. Then, they performed a sequence motor task assigned by the Serial Reaction Time Task software in the three phases of acquisition, retention, and transfer. In order to analyze the data, ANOVA with repeated measures, Wilcoxon test, Mann-Whitney U test and the independent samples t-test were conducted.

Conclusion: Errorfull and errorless training are effective on reaction time and amount of errors in the retention and transfer stages of a motor sequential task in elderly women. However, It is suggested that trainers use errorfull training methods in motor sequential tasks in order to reduce the error rate and provide a more optimal learning environment.
Evaluatin of Association of rs4986790 and rs4986791 Single-Nucleotide Polymorphisms in TLR4 with Febrile Neutropenia in Childhood Acute Lymphoblastic Leukemia
Authors: Delkhah Mona , Arasteh Javad , Koochakzadeh Leili , Rostami Shahrbano 
Published: July 2023

Background: Infections cause significant complications and, in severe cases, death in patients with childhood Acute Lymphoid Leukemia (ALL). Toll-like receptors (TLRs) play a crucial role in initiating innate immune responses. Previous studies indicate the role of TLR4 gene polymorphisms in the increased risk of infection in adults and children. This study investigated the potential association between Asp299Gly (rs4986790) and Thr399Ile (rs4986791) polymorphisms in the TLR4 gene with febrile neutropenia, as a hallmark of infection, in children with ALL.
Material and Methods: This cross-sectional study was performed on 51 ALL child patients, with age (mean±s.d.) 5.2 ± 3.4 years. Genotype analysis of rs4986790 and rs4986791 polymorphisms in the TLR4 gene was evaluated by ARMS- PCR and PCR-RFLP, respectively. Statistical analysis was performed using SPSS software. P-values <0.05 were considered significant.
Results: The rs4986790 and rs4986791 polymorphisms were detected in 5.8% and 7.8% of ALL patients, respectively. The mean of recurrence of febrile neutropenia in patients without TLR4 rs4986790 and TLR4 rs4986791 polymorphisms was 3.1 ±2 and 3 ±1.9, respectively, while in patients with TLR4 rs4986790 and TLR4 rs4986791 polymorphisms, they were 4.6 ± 3 and 5.2 ±2.8, respectively (P = 0.09). No association was found between TLR4 rs4986790 and rs4986791 polymorphisms and the number of febrile neutropenia recurrences (P = 0.4).
Conclusion: Although rs4986790 and rs4986791 polymorphisms were detected in ALL patients, these polymorphisms were not associated with febrile neutropenia. It is suggested to investigate other polymorphisms in immune system-related genes and their role in febrile neutropenia.
Evaluating the effects of chemotherapy drugs and thiosemicarbazone complexes on the alteration of SNHG16 expression in Acute Lymphoblastic Leukemia
Authors: Erfanipour Fatemeh , Ghorbani Fatemeh , Mirzaahmadi Sina , Asaadi Tehrani Golnaz 
Published: July 2023

Background: Acute lymphoblastic leukemia (ALL) is a malignant disease that afflicts both children and adults. It starts from the bone marrow (soft and spongy tissue inside the bone) where immature white blood cells or lymphocytes are formed. This study aims to compare chemotherapy drugs, methotrexate (MTX), cyclophosphamide, cytarabine (Ara-C) and mercaptopurine (6mp) with nickel (Ni) and copper (Cu) complexes of thiosemicarbazone (TSCZ) in terms of their effects on the changes of Small Nucleolar RNA Host Gene 16(SNHG16) long non coding RNA (lncRNA) expression in the ALL cell line.
Materials and Methods: this experimental study was conducted on various concentrations of chemotherapy drugs including MTX, CP, Ara-C, 6mp and Ni and Cu complexes of TSCZ. The Jurkat E6.1 cell lines were subjected to passage in different groups and times (24, 48, and 72h) and then treated with the chemotherapy drugs. After RNA extraction and cDNA synthesis, the SNHG16 gene expression was evaluated by Real-Time PCR, and the results were analyzed by the Rest software.
Results: As the results indicated, within 24h, MTX (0.77, 0.72), CP (0.61, 0.7), ara-C (0.78, 0.87), Cu (0.91, 0.95) and Ni (0.94, 0.79) complexes as well as complex 1(0.73) and 2 (0.94) decreased the expression of SNHG16 gene significantly (P<0.001). Furthermore within 48h, under the influence of CP (0.86, 0.89) and Ara-C (0.94, 0.97) as well as Cu (0.96) and Ni (0.98) complexes, the gene expression continued to decline(P<0.001).The greatest effect of chemotherapy drugs belonged to the combination of 1μM of ara-C and 5μM of 6mp.(P<0.001).
Conclusion: It was found that gene expression analysis is a feasible method to identify the pathways affected by the standard induction chemotherapy in ALL patients. This finding promotes the development of novel targeted drugs and biomarkers to categorize disease aggressiveness and evaluate treatment responses.
The management and approach to osteosarcoma in children: A mini-review article
Authors: Yazdanparast Maryam Sadat , Ghilian Mohammad Mahdi , Sheikhpour Elnaz 
Published: July 2023

Osteosarcoma (OS) is the most common type of primary malignant bone tumor. The onset of OS is associated with local pain and swelling as well as joint dysfunction, occasionally. The most common location for OS is around the knee joint. These patients often tend to receive medical attention following physical exercise and trauma. The affected population is mainly teenagers, children, and young adults with age range of 10-30 years.
OS can be diagnosed via different approaches. The main serum markers for pediatric OS are insulin‑like growth factor (IGF‑1 and IGFBP‑3), anti‑ki57 antibody, tumor necrosis factor (TNF)‑β and sTNF‑R, T3, CD44, vascular endothelial growth factor, serum amyloid A, CXC chemokines, bone alkalin phosphatase, Interleukin (IL‑2, IL‑4, IL‑8), interferon gamma (IFN-γ), TNF‑α, and free polyamines.
Given that there is no comprehensive review literature regarding OS management in our country, this study aimed to assess a survey on the management and approach of OS in children. In this regard, we have discussed the epidemiology, etiology, type, clinical feature, diagnosis, and OS therapy.
A Comparison between TTR and FIR as a Measure of the Quality of Anticoagulation in Patients with Atrial Fibrillation
Authors: Parbhoo Priya , Jacobson Barry 
Published: July 2023

Abstract

Background: Atrial fibrillation (AF) is a growing concern worldwide. In order to prevent AF-related adverse vascular events, adequate oral anticoagulation with warfarin is essential. The Rosendaal method has long been used to calculate time in therapeutic range (TTR) in clinical trials to assess the quality of anticoagulation but now suffers dwindling popularity due to its tedious method of calculation and inability to account for the duration spent in an out-of-range international normalized ratio (INR). Frequency in range (FIR) is being reassessed as to its value as it is easier to calculate.

Objectives: We aimed to compare FIR and TTR (using the Rosendaal method) as a measure to assess the quality of anticoagulation with warfarin in a cohort of 102 consecutive patients with valvular and non-valvular AF at a tertiary South African hospital. Secondary objectives were to assess the predictive ability of FIR to categorize patients with a TTR ≥ 65% as well as to compare the CHA2DS2VASc and HASBLED scores with TTRs and FIRs.

Methods: We retrospectively analysed the INR values for all patients over a 2-year period and calculated both individual and overall mean TTR and FIR and assessed the agreement between these parameters.

Results: The mean overall TTR was 58.1% ± 16% and the mean FIR was 50.8% ± 16.7%. The mean TTR was significantly higher than the mean FIR (p < 0.0001). At the individual level, FIR was positively correlated with TTR in a linear fashion (
r
= 0.93, p < 0.001). However, the Bland–Altman method plot indicated lack of agreement between TTR and FIR, with a bias of 7.4% (95% CI: 6.1%–8.6%) and limits of agreement −4.6% to 19.3%, standard deviation (SD) = 6.1%. A cut-off value of FIR ≥ 53.3% was found to be a good predictor of TTR ≥65%.

Conclusion: Our study shows that although TTR and FIR are highly correlated with the individual INR levels, they are not equal. The two methods cannot be used interchangeably to assess warfarin control, and TTR should probably remain the gold standard.
Vocational Rehabilitation for Seasonal and Migrant Farmworkers in California: A Personal Narrative
Authors: Longoria Domingo Chris , Degeneffe Charles Edmund 
Published: July 2023

Background:Little is known in the rehabilitation counseling profession regarding the needs and rehabilitation approaches used with seasonal and migrant farmworkers in the United States.Objectives:The purpose of this article is to provide rehabilitation counselors with awareness of the vocational needs of seasonal and migrant farmworkers. The article also provides best practice approaches to effectively provide vocational rehabilitation (VR) services to this population.Method:The article presents a first-person narrative by a recently retired rehabilitation counselor with more than 30 years of practice experience with the California Department of Rehabilitation. The bulk of this career focused on meeting the VR needs of migrant and seasonal farmworkers.Findings:The first-person narrative conveys best practice approaches with outreach, vocational assessment, partnerships, and job placement found helpful with seasonal and migrant farmworkers.Conclusions:To date, the rehabilitation counseling profession has largely ignored seasonal and migrant farmworkers. We hope the readers of this article will place greater professional attention on meeting the VR needs of this population in funding, program development, and training.
Simultaneous Quantification of 16 Bisphenol Analogues in Food Matrices
Authors: Lucarini Fiorella , Gasco Rocco , Staedler Davide 
Published: July 2023

Exposure to bisphenol analogues can occur in several ways throughout the food production chain with their presence at higher concentrations representing a risk to human health. This study aimed to develop effective analytical methods to simultaneously quantify BPA and fifteen bisphenol analogues (i.e., bisphenol AF, bisphenol AP, bisphenol B, bisphenol BP, bisphenol C, bisphenol E, bisphenol F, bisphenol G, bisphenol M, bisphenol P, bisphenol PH, bisphenol S, bisphenol Z, bisphenol TMC and tetramethyl bisphenol F) present in canned foods and beverages. Samples of foods and beverages available in the Swiss and EU markets (n = 22) including canned pineapples, ravioli and beer were prepared and analyzed using QuEChERS GC-MS. The quantification method was compared to a QuEChERS LC-MS/MS analysis. This allowed for the selective and efficient quantitative simultaneous analysis of bisphenol analogues. Quantities of these analogues were present in 20 of the 22 samples tested with the most frequent analytes at higher concentrations; BPA and BPS being discovered in 78% and 48% of cases respectively. The study demonstrates the robustness of QuEChERS GC-MS for determining low quantities of bisphenol analogues in canned foods. However, further studies are necessary to achieve full knowledge of the extent of bisphenol contamination in the food production chain and its associated toxicity.
The level of service ability in the final four 2019 pro league men's players
Authors: Aprilian Kalvin , Muharram Nur Ahmad , Kurniawan Wing Prasetya 
Published: July 2023

<strong><em>This research is based on observations in the form of an analysis of the level of difficulty of the service performed by each player depending on the type of service used, such as floating service, jump float, and jumping service top spin. A good service is the direction of the ball to the empty side of the field or between two players. It is intended for when the opponent receives a service in a moving position or creates a misunderstanding between two players because the ball is between the two players. The service above is the type of service that is often done by players from the beginner level to the professional level. However, there are still many professional players who competed in the 2019 proliga, the first round of the men's sector, not all of them know what type of service is most productive. In accordance with the problem formulation, the purpose of this research is to determine the level of ability of floating service, jump float service and jumping service top spin in the final four proliga 2019 men's volleyball. This study uses a survey method with data collection techniques using observations (observations) by judges and document analysis (video). The conclusion from the research that has been done is that the results of each team regarding service ability are the ability of floating service of 8.88 and if presented in percentage form, it is 11.27%, Jump float service ability is 33.63 and if presented in percentage form, it is 42, 65%, the ability to jump service top spin is 36.33 and if it is presented as a percentage, it is 46.08%. From the discussion, it was concluded that the level of service ability in the 2019 proliga men's volleyball final according to the results of observations and observations through video observations, it was concluded that the Jumping service Top Spin had the highest ability value compared to the service float and jump float of 46.08%. </em></strong>
Mineral–Geochemical and Geotectonic Features of the Lotmvara-II Ultrabasic Sill, Serpentinite Belt (Kola Peninsula)
Authors: Barkov A.Y. , Nikiforov A.A. , Korolyuk V.N. , Martin R.F. 
Published: July 2023

Abstract
—In this paper, we present a description of the characteristics of the Lotmvara-II sill, which is a representative of the Serpentinite Belt (SB) composed of a series of shallowly emplaced ultrabasic intrusive bodies. The Paleoproterozoic SB complexes were derived from a large-scale mantle plume of komatiitic melt. The sill consists predominantly of fine-grained (locally nearly micrograined) harzburgites with subordinate zones of dunites and orthopyroxenites, located in the central and marginal parts, respectively. It formed from an Al-undepleted komatiitic magma of extremely high Mg content and may represent a near-surface laccolithic “ridge.” In general, the sill is comparatively homogeneous and does not have distinct zoning in the distribution of Mg# values in rock compositions (Mg# = 84.2–88.9, average 86.7). Detailed studies show that olivine, chromian spinel, and ilmenite are the most strongly magnesian in the central part of the body. The maximum values of Mg# equal to 90.7–91.4 in the compositions of olivine at the center of the sill are interpreted as “centers of initial crystallization”. The low values of Mg# equal to 73.4–76.4 are attributed to manifestations of the recurrent generation of olivine. The values of Mg# of orthopyroxene in the sill are within the range 84.6 to 92.3. Orthopyroxene grains in a porphyritic texture are surrounded by a rim of calcic amphibole (autometasomatic in origin); they do not differ compositionally from normal grains. The Zn content of the chromian spinel generally decreases toward the marginal parts of the sill. There is an insignificant degree of magmatic differentiation in the sill with respect to the principal components, but incompatible elements (REE and HFSE) locally show increased levels of their relative enrichment, which is reflected in the nature of the mineral associations described. Thus, the sill has a cryptic zonal structure, which is consistent with its overall crystallization from the center to the edges. The data gathered suggest the presence and significant development of volatile components, halogens, CO2, and especially magmatic H2O, which are capable of strongly lowering the liquidus and reducing the density and viscosity of the high-magnesium melt, thereby improving its mobility during ascent from the mantle to the near-surface level of the crust. An increase in fO2 is observed during in situ subvolcanic crystallization of the sill, as noted earlier in the related complexes of the belt. The relatively small volume of the komatiitic magma in the sill crystallized fairly quickly, resulting in unusual mineral intergrowths. Thus, the Lotmvara-II sill is a novel member in the Serpentinite Belt–Tulppio Belt (SB–TB) in the Paleoproterozoic SB–TB megastructure of the Fennoscandian Shield.
Mapping the virtual water trade in water-scarce basin: An environmentally extended input-output analysis in the Yellow River Basin of China
Authors: Zhang Bin , Niu Niu , Li Hao , Tao Huawei , Wang Zhaohua 
Published: July 2023

Abstract
The mismatch between the distribution of water resources and the industrial structure has led to an increasingly prosperous regional trade, with many water resources flowing from the production to the consumption regions. This paper maps the inside and outside virtual water trade of the Yellow River Basin, applying the environmentally extended input-output model to evaluate the external dependence of water in the Yellow River Basin. The results show that the Yellow River Basin mobilizes 27.2 billion of virtual water flowing into other regions despite water scarcity, equivalent to half the runoff of the Yellow River. The leading destination for outflow is the Eastern coast, and the largest virtual water outflow sector is Agriculture and Manufacturing. The inequity of the inside virtual water trade of the Yellow River Basin is severe, with large amounts of virtual water flowing from poor to rich regions. It exacerbates water scarcity in poor regions.
Economic Sanctions and Environmental Degradation in Iran
Authors: Maddah Majid 
Published: July 2023

Abstract

Iran faces three issues: severe international sanctions, environmental problems, and low institutional quality. Their coexistence makes it challenging to achieve sustainable development goals. While considering the relationship between three issues of sanctions, environmental quality, and corruption, this study investigates the effect of economic sanctions on environmental degradation in Iran using the Partial Least Square of Structural Equation Modeling (PLS-SEM) method during the years 1996-2019. According to the findings, in the short run, economic sanctions directly and positively affect environmental degradation in Iran. Sanctions also have an indirect positive and significant effect on environmental degradation in such a way that intensifying sanctions threaten the environmental quality through corruption channel. Our findings highlight the international attention to the environmental effects of economic sanctions against Iran.
JEL Classification: F51, Q56, D73, C39, O53.