bluuebunny/crossref_metadata_2025_split huggingface dataset:
Peri-operative management of diabetes mellitus - A survey of current practices among Indian anesthesiologists
Authors: Priya Vansh , Bais Prateek S. , Rastogi Amit , Shamim Rafat , Aggarwal Anil , Patro Abinash 
Published: May 2023

Abstract

Background and Aims:
Increased burden of diabetes in India has resulted in a spurt in the number of patients with diabetes posted for surgeries. The paucity of national guidelines can lead to marked practice variations in the peri-operative management of diabetes. This survey intends to discern current peri-operative practices among anesthesiologists working in medical colleges, tertiary care government, and private health care institutes of the country.

Material and Methods:
An anonymous online survey comprising of 25 closed-ended questions was conducted using Google Forms® and disseminated through social media, emails, and messaging platforms. The questionnaire dealt primarily with the peri-operative management of diabetes in patients scheduled for elective surgery. The survey was conducted over a period of 1 month and targeted anesthesia resident trainees with more than 1-year experience, senior residents, and consultants working in India.

Results:
Statistically significant difference was observed between the three types of health facilities with respect to prior evaluation for diabetes (P = 0.007), prioritizing operative list (P = 0.006), hospital encouragement of day care surgery (P < 0.001), glycated hemoglobin level (HbA1c) level >8.5 for postponement of surgery (P < 0.05), insulin infusion preference (P < 0.001), hourly intra-operatively capillary blood glucose (CBG) assessment (P = 0.021), and avoiding peri-operative use of Ringer’s lactate (RL) (P = 0.025).

Conclusion:
This survey primarily highlights the lack of prioritizing the operative list, early discontinuation of metformin, and reduced tendency to consider diabetics for day care surgeries.
Salsalate Improves Postprandial Glycemic and Some Lipid Responses in Persons With Tetraplegia: A Randomized Clinical Pilot Trial With Crossover Design
Authors: Kressler Jochen , Mendez Armando , Betancourt Luisa , Nash Mark 
Published: May 2023

Objectives
To investigate the effects of salsalate on fasting and postprandial (PP) glycemic, lipidemic, and inflammatory responses in persons with tetraplegia.

Methods
This study was a randomized, double-blind, cross-over design. It was conducted at a university laboratory. Ten males aged 25 to 50 years with SCI at C5-8 levels for ≥1 year underwent 1 month of placebo and salsalate (4 g/day) treatment. Blood samples were drawn before and 4 hours after breakfast and lunch fast-food meal consumption.

Results
Descriptive statistics indicate that fasting and PP glucose values were reduced with salsalate (pre-post mean difference, 4 ± 5 mg/dL and 8 ± 8 mg/dL, respectively) but largely unchanged with placebo (0 ± 6 mg/dL and -0 ± 7 mg/dL, respectively). Insulin responses were generally reciprocal to glucose, however less pronounced. Fasting free fatty acids were significantly reduced with salsalate (191 ± 216 mg/dL, p = .021) but not placebo (-46 ± 116 mg/dL, p = .878). Results for triglycerides were similar (25 ± 34 mg/dL, p =.045, and 7 ± 29 mg/dL, p = .464). Fasting low-density lipoprotein (LDL) levels were higher after salsalate (-10 ± 12 mg/dL, p = .025) but not placebo (2 ± 9 mg/dL, p = .403) treatment. Inflammatory markers were largely unchanged.

Conclusion
In this pilot trial, descriptive values indicate that salsalate decreased fasting and PP glucose response to fast-food meal challenge at regular intervals in persons with tetraplegia. Positive effects were also seen for some lipid but not for inflammatory response markers. Given the relatively “healthy” metabolic profiles of the participants, it is possible that salsalate's effects may be greater and more consistent in people with less favorable metabolic milieus.
PENGARUH MODEL PEMBELAJARAN CONNECTED MATHEMATICS PROJECT (CMP) BERBANTUAN GOOGLE SITE TERHADAP KEMAMPUAN PEMAHAMAN KONSEP MATEMATIS
Authors: Buraidah Nur Layaliya , Rahmawati Fadhilah 
Published: May 2023

The purpose of this study was to analyze the ability to understand mathematical concepts of students who were taught with the Google Site-assisted CMP learning model better than those taught with the direct learning model. The next objective is to analyze the ability to improve understanding of mathematical concepts taught with the Google Site-assisted CMP learning model for derived material. This research is quantitative research with quasi-experimental design. The nonequivalent control group design was used as a form of quasi-experimental, by comparing two samples of 44 students from class XI MIPA SMA Negeri 2 Magelang who were randomly selected. From the Independent Sample t-Test test it produces a value of then is rejected and is accepted which means the ability to understand mathematical concepts taught with the Google Site-assisted CMP learning model is better than the direct learning model. Then, the average N-Gain test was 0.38 and proved that there was an increase taught by the Google Site-assisted CMP learning model for derivative material in the medium category. From the results of hypothesis testing, it can be concluded that the ability to understand mathematical concepts taught by the Google Site-assisted CMP learning model is better than the direct learning model for derivative material, and there is an increase in the moderate category.
PERAN MEDIA SOSIAL (YOUTUBE) DALAM MENINGKATKAN KREATIVITAS SISWA KELAS VIII DI SMP NEGERI 45 MEDAN TAHUN PEMBELAJARAN 2022/2023
Authors: Simanullang Doni Rio , Baene Efina Katarina , Nababan Rosma , Manullang Manahan 
Published: May 2023

Penelitian ini dilakukan dengan tujuan untuk mengkaji bagaimana peran media social (youtube) meningkatkan kreatifitas siswa SMP Negeri 45 Medan. Jenis penelitian ini menggunakan penelitian pendekatan deskriptif kualitatif dan metode penelitian kualitatif. Metode kualitatif adalah metode yang di gunakan dalam mengetahui keadaan yang sedang di teliti yaitu subjek, tempat dan bagaimana pelaksanaan penelitian bagi siswaSMPN 45 Medan terkait penggunaan media sosial terhadap kreatifitas belajar siswa. Teknik pengumpulan data yang dilakukan dalam penelitian ini ialah data primer dan data sekunder. Data primer ialah data yang di terima langsung melalui narasumber yangdijadikan sebagai objek dalam penelitian. Sedangkan data sekunder ialah yakni buku, jurnal ilmiah, atau artikel lainnya yang dapat membantu dalam penelitian ini. Teknikanalisis data dalam penelitian ini ialah reduksi, penyajian data, dan penarikan kesimpulan. Penelitian ini bertujuan untuk mengetahui bagaimana penggunaan media sosial terhadap kreatifitas belajar siswa melalui media (youtube.) Teknik pengumpulan data yang dilakukan dalam pengumpulan data ini adalah data primer dan data sekunder. Data primer adalah data yang diterima langsung melalui orang yang dijadikan sebagai objek penelitian yaitu wawancara dengan 16 orang narasumber, 1 orang guru PPKn dan 15 orang siswa di SMP Negeri 45 Medan, Sedangkan data sekunder yaitu buku, jurnal ilmiah, atau artikel yang membantu untuk melakukan penelitian ini. Dalam pengumpulan intstumen data, peneliti menggunakan metode observasi, wawancara, serta dokumentasi di lokasi penelitian, sedangkan untuk teknis analisis data dalam penelitian ini adalah reduksi, penyajian data dan penarikan kesimpulan. P enelitian ini dilaksanakan di SMP Negeri 45 Medan, Berdasarkan hasil penelitian di lokasi penelitian bahwa untuk Peran Media Sosial (youtube) sudah sangat baik dan sangat membantu siswa untuk meningkatkan kreativitas,belajar,mengamati,menganalisa dan mengaplikasikan, meski ada kendala tetapi kehadiran media sosial sangat membantu Siswa untuk mendapatkan informasi dan mengasah kreativitas.
HUBUNGAN ANTARA PEMAHAMAN SISWA TENTANG PENEGAKAN TATA TERTIB DENGAN KEDISIPLINAN SISWA DI SMP NEGERI 21 MEDAN TAHUN 2022
Authors: Waruwu Notakris Masyah Putra , Hutapea Dean F.H , Nababan Rosma 
Published: May 2023

Penelitian ini dilakukan untuk mengetahui Hubungan Antara Pemahaman Siswa Tentang Penegakan Tata Tertib dengan Kedisiplinan di Siswa SMP Negeri 21 Medan tahun 2022. Jenis penelitian ini dengan menggunakan metode kuantitatif deskriptif korelasional. Di mana populasi dalam penelitian ini adalah seluruh siswa Siswa SMP Negeri 21 Medan tahun 2022 dan sampel dalam penelitian ini berjumlah 35 orang yang dipilih dengan sistem acak. Instrumen yang digunakan dalam penelitian ini yaitu angket tata tertib dan angket kedisiplinan dengan empat pilihan (a,b,c,d). Dimana angket penegakan tata tertib dan angket kedisiplinan masing-masing berjumlah 16 soal. Angket yang digunakan dalam penelitian ini terlebih sudah diuji Validitas dan Reliabilitas anya. Hasil uji normalitas data penegakan tata tertib pada taraf signifikan 5% diperoleh ²ℎ<² (4,425< 67,50) dan kedisplinan siswa diperoleh ²ℎ<² (38,82 < 67, 50), maka data dua variabel penelitan disimpulkan berdistribusi normal. Hasil uji persyaratan linearitas data antara pemahaman siswa tentang penegakan tata tertib dengan kedisiplinan siswa SMP Negeri 21 Medan tahun 2022 adalah linier, dengan persamaan Y = 38,43 + 0,29 x, dikonsultasikan dengan ℎ> (48,013 > 0,020). Hasil uji kecenderungan penegakan tata tertib sekolah dikategotorikan sedang (50%) dan pertumbuhan kedisplinan siswa dikategorkan sedang (36%). Berdasarkan hasil analisis koefisien korelasi diperoleh ℎ (0,298)> (0,279), hal ini menunjukkan ada hubungan antara pemahan siswa tentang penegakan tata tertib dengan kedisiplinan siswa SMP Negeri 21 Medan tahun 2022. Hasil uji “t” pada taraf signifikan 5%, kedisplinan diperoleh ℎ> (2,151 > 1,675). Hal ini menunjukkan ada hubungan yang signifikan antara pemahan siswa tentang penegakan tata tertib dengan kedisiplinan siswa SMP Negeri 21 Medan tahun 2022
Peningkatan Kemampuan Berpikir Kritis Siswa Melalui Pembelajaran Pairs Check Pada Materi Limit Fungsi Aljabar
Authors: Toybah Annisa , Safitri Friantiani , Khaulah Siti 
Published: May 2023

Penelitian bertujuan untuk mengetahui peningkatan kemampuan berpikir kritis matematis siswa melalui model pembelajaran Pairs Check. Pendekatan penelitian yang digunakan adalah pendekatan kuantitatif, jenis penelitian eksperimen dengan rancangan One Group Pretest-Postest Design. Populasi dalam penelitian ini adalah seluruh siswa kelas XI SMA Negeri 3 Bireuen tahun ajaran 2020/2021. Sampel diambil satu kelas, yaitu kelas XI MIPA 2 dengan jumlah siswa 19 orang dari keseluruhan populasi yang dipilih dengan menggunakan teknik random sampling. Pengumpulan data dilakukan dengan melakukan tes dan observasi. Data hasil tes yang telah terkumpul di uji nilai gain ternormalisasi dan didapatkan hasilnya berada di kriteria sedang, selanjutnya data Pretest dan Postest dianalisis menggunakan statistik uji-t. Setelah dilakukan pengolahan data, diperoleh thitung > ttabel, yaitu 3,314 > 2,12, maka hasil hipotesis Ho ditolak dan hipotesis Ha diterima. Sehingga dapat disimpulkan bahwa terdapat peningkatan kemampuan berpikir siswa melalui pembelajaran Pairs Check dan proses kegiatan belajar menggunakan model pembelajaran Pairs Check termasuk dalam kategori sangat baik dan sesuai dengan yang direncanakan.
Analisis Kemampuan Pemecahan Masalah Matematis Siswa Dengan Model Pembelajaran Team Quiz Materi Operasi Bilangan Bulat
Authors: Nufus Hayatun , Rohantizani Rohantizani 
Published: May 2023

Tujuan penelitian ini adalah menganalisis kemampuan pemecahan masalah matematis siswa setelah diterapkan model pembelajaran Team Quiz pada materi Operasi Bilangan Bulat. Penelitian ini menggunakan pendekatan kualitatif dengan jenis penelitian deskriptif. Adapun teknik pengumpulan data pada penelitian ini adalah test kemampuan pemecahan masalah matematis siswa dan wawancara. Sedangkan teknik analisis data yang digunakan dalam penelitian ini adalah triangulasi. Berdasarkan hasil tes yang diikuti oleh 10 siswa diperoleh bahwa subjek 1 dan subjek 2 sudah 80% dan 78,5 % menguasai indikator pemecahan masalah matematis. Selanjutnya, persentase kemampuan pemecahan masalah matematis subjek 3 dan subjek 4 adalah 81,25% dan 62,5%. Adapun persentase untuk subjek 5 adalah sebesar 76,25%. Selain itu, persentase kemampuan pemecahan masalah matematis subjek 6 dan 7 adalah 57,5%. Kemudian, hasil tes yang diperoleh subjek 8 adalah 46,25% menguasai indkator pemecahan masalah matematis. Selanjutnya, subjek 9 dan subjek 10 hanya 40% dan 33,75%. menguasai indikator pemecahan masalah matematis. Adapun rata-rata kemampuan pemecahan masalah matematis siswa adalah 61,38%. Berdasarkan hasil post test dan wawancara diperoleh bahwa kesepuluh subjek lebih menguasai indikator pemecahan masalah matematis pada soal nomor 5.
Penerapan Pembelajaran Problem Based Learning Untuk Meningkatkan Kemampuan Berfikir Kritis Siswa Pada Teorema Pytagoras
Authors: Jannah Miftahul , Nuri Bulan 
Published: May 2023

Tujuan penelitian ini adalah untuk mengetahui adanya peningkatan kemampuan berpikir kritis matematis siswa dengan penerapan model pembelajaran Problem Based Learning (PBL) dibandingkan model pembelajaran konvensional pada materi Teorema Pytagoras. Penelitian dengan pendekatan kuantitatif ini mengambil sampel 2 kelas di SMP Negeri 1 Peusangan, yaitu kelas VIII-7 sebagai kelas eksperimen dan kelas VIII-5 sebagai kelas kontrol dengan jumlah siswa masing-masing kelas 25 orang. Data dianalisis dengan menggunakan tes dan observasi. Hasil pengujian dengan hipotesis menggunakan uji t dengan taraf signifikan α = 0,05 diperoleh > ( 3,77 > 1,68 ), sehingga ditolak dan diterima. Dengan demikian, pembelajaran dengan model Problem Based Learning lebih baik dalam meningkatkan kemampuan berpikir kritis matematis siswa dari pada model pembelajaran konvensional pada materi Teorema Pytagoras.
Studies on antioxidant potential and total phenolic contents of dried powder and pulp of raw and ripe Carica papaya fruit
Authors: Bhardwaj Madhvi , Mahajan Babita , Kumar Ankush , Parcha Versha 
Published: May 2023

Introduction and Aim: Antioxidants are frequently used as active ingredients in anti-aging supplements with the intention of preserving health and preventing diseases. However, recent research has concentrated on conventional therapies that have a long history of successfully treating several diseases. C. papaya is a good alternative and exhibits significant antioxidant, diuretic, antihyperglycemic, anticancer, analgesic, and depressive properties from a key plant constituent. In this study, total phenolic content, and antioxidant potential of raw and ripe Carica papaya were examined.

Materials and Methods: C. Samples of raw and ripe Carica papaya were collected from the local market of Dehradun. Dried powder and fresh pulp of the raw and ripe Carica papaya was individually subjected to phytochemical test principles. Total phenolic contents were estimated using the Folin-Ciocalteu and antioxidant potential using DPPH and ferric chloride reducing power assay method.

Results: The fresh pulp and powder of ripe Carica papaya showed high content of phenolics in fresh ripe pulp, fresh raw pulp, dried ripe powder and raw dried powder as 200, 195,185 7 mg/100 g respectively with an antioxidant activity DPPH radical scavenging activity, 80.2, and 75. .76.4 and 74.5 respectively which is comparable to butylated hydroxy anisole (BHA) and diphenhydramine (DPPH) radical scavenging activity.

Conclusion: The fresh pulp and powder of ripe Carica papaya showed wide antioxidant activity (DPPH) radical scavenging activity. Hence, it can be effectively used as an organic substitute for chemical compounds (BHA, BHT) which have a lot of harmful side effects. Moreover, phytochemical studies of Carica papaya have shown the presence of phenolic compounds well justified by estimation of content which are responsible for its potent antioxidant activity.
Blood culture and profile of inflammatory biomarkers among COVID-19 patients in an intensive care unit of a tertiary care hospital
Authors: P. P. Asif , C. Tellis Rouchelle , Sunil Lobo Amar , Motagi Aravind 
Published: May 2023

Introduction and Aim: This is a retrospective study to analyse the pathogens causing bacteraemia in COVID-19 patients and its correlation with inflammatory biomarkers such as procalcitonin (PCT), C-reactive protein (CRP), total WBC counts (TC) and D-dimer. The objectives of this study were to evaluate the blood culture positivity rate, to identify the pathogens causing bacteraemia, to analyse their antibiogram and to assess the significance of inflammatory markers along with patient outcomes.

Materials and Methods: This study included 165 COVID-19-positive patients admitted to the Intensive care unit (ICU) of a tertiary care hospital from June to September 2020. Blood culture, identification and antibiotic sensitivity testing (AST) were done using automated systems. Values of D-dimer, CRP, PCT and TC were obtained using immunoturbidimetric assay, chemiluminescent immunoassay, immunochromatographic testing and automated haematology analyser respectively.

Results: Among 143 blood culture samples obtained from 122 COVID-19 positive patients, 80 flagged positive. Out of the 80 isolates obtained, 53 (66.25%), 17 (21.25%) and 10 (12.5%) were gram-positive bacteria, gram-negative bacteria and candida respectively. The blood culture positivity rate was 25.4%. Acinetobacter spp. and K. pneumoniae showed high levels of antibiotic resistance. Among 16 patients with elevated PCT, 15 (93.7%) patients showed positive blood cultures. CRP of >5 mg/L and deranged total WBC counts were seen among all blood culture-positive patients. In 100 patients with elevated D-dimer, 54% (54/100) patients showed positive blood culture.

Conclusion: From this study, we conclude that early identification of pathogens and initiation of appropriate antimicrobial therapy is crucial for managing sepsis associated with COVID-19 infection. PCT, CRP, TC and D-dimer can help as biomarkers in the management of COVID-19 patients with secondary bloodstream infections (BSI).
A reappraisal of Gaucher disease patients - Clinical presentation, and diagnosis in rare disease unit of central child teaching hospital in Baghdad province
Authors: Ali Ahmed Ikhlas , Abbas Fadhel Alaa 
Published: May 2023

Introduction and Aim: Gaucher disease (GD) is an autosomal recessive ailment caused due to mutations in the GBA1 gene, encoding for the lysosomal enzyme, glucocerebrosidase. The aim was to evaluate the clinical, biochemical, and molecular parameters associated with this disease, as well as to identify symptoms and covariables thought to be most diagnostic of early GD presentation, allowing for early diagnosis and management.

Methodology: This cross-sectional study involved twenty-six patients diagnosed with GD at the Metabolic Department of Central Child Teaching Hospital, Baghdad, Iraq. Diagnosis depended mainly on history and physical examination and confirmed by beta-glucosidase enzyme assay of dry blood spot on filter paper and Lyso-GL-1 level. Amplification-based next generation sequencing approach was used in investigating the GBA1 gene at the molecular level.

Results: The mean age of the 26 (17 male and 9 female) patients was 9.13 years, with 100% consanguinity and 50% positive family history. The average number of years from the start of clinical manifestations to the diagnosis' validation was 3.82 years. The original age of presentation was 2.83 years, and the initial age of diagnosis was 6.65 years. Hepatosplenomegaly (85%), pallor (88%), splenomegaly (12%), splenectomy (12%), hemorrhage (19%), bone discomfort (23%), bone breakage (12%), and GD type III (19%) were observed. Among patients 65% exhibited radiological bone abnormalities, 54% had Erlenmeyer flask deformity, and 1.5% had osteopenia and fracture. Studies of GBA1 gene showed the mutation C.[1448T>c ](P.[ Leu483Pro] to be the most common. Hepatosplenomegaly and hematological deficiencies were effectively improved by enzyme replacement therapy.

Conclusion: In Gaucher disease, GBA1 gene mutation analysis could provide some predictive information about disease variance as well as severity. PCV%, platelet count, ferritin, and lyso-GL-1 levels could be employed as biomarkers for the diagnosis of GD. ERT proved effective in treating hematological and hepatosplenomegaly abnormalities.
A safety profile of Siddha formulation Karisalai Chooranam in Wistar albino rats
Authors: S. Mary Princess Sulekha , G. Dayanand Reddy , A. Muthuvel 
Published: May 2023

Introduction and Aim: Karisalai Chooranam (KSC) is used in the traditional Siddha system of medicine for a long time to treat various ailments in the body. Its antistress and antioxidant properties were reported earlier. Investigating the acute and long-term toxicity of Karisalai Chooranam in Wistar albino rats was the goal of the current study.

Materials and Methods: For the acute toxicity investigation, Wistar rats were divided into four groups. For fourteen days, the animals were monitored for behavioural changes and toxicological complaints. For ninety days, a total of four categories of animal groups like control, forty mg/kg body weight, two hundred mg/kg body weight and thousand mg/kg body weight were utilized in a long - term toxicity study. The samples of blood were taken on the final day of the trial for biochemical and haematological examination. Animals were sacrificed for monitoring gross necropsy changes and histopathological examination of the liver, kidney and brain.

Results: There was no morbidity or death observed in the acute toxicity trial. In the research of long - term toxicity. KSC's haematological and biochemical parameters during analysis did not exhibit any appreciable changes. All the three doses of KSC, the renal and brain histology displayed normal architecture. When the medicine was given to the forty milligram and two hundred milligram dosage groups of animals for 90 days, no toxicity symptoms were present in the case of organ liver. After the medicine was given for 90 days to the thousand milligram dosage group, toxic signs such as programmed and localized cell death became apparent.

Conclusion: Toxicity studies proved the safety of KSC in animal models. If KSC is utilized clinically as prescribed in literature, it will not cause any adverse effects.
Müzik Eğitimi Anabilim Dallarında Keman Eğitimi Veren Akademisyenlerin Dört Keman İçin Orijinal/Aranje Edilmiş Eserleri Tanıma ve Kullanma Durumları
Authors: KAPÇAK Şeydagül , KAPÇAK IŞIKSUNGUR Beyzagül 
Published: May 2023

Araştırmada Türkiye’deki Müzik Eğitimi Anabilim Dallarında keman eğitimi veren akademisyenlerin dört keman için orijinal/aranje edilmiş eserleri tanıma ve kullanma durumlarının ortaya konulması amaçlanmıştır. Araştırma nitel çerçevede gerçekleştirilen bir durum çalışmasıdır. Araştırmanın çalışma grubunu; Türkiye’deki her bir coğrafi bölgeden seçilmiş bir üniversitenin Müzik Eğitimi Anabilim Dalında görev yapan keman eğitimcileri oluşturmaktadır. Araştırmanın çalışma grubu; amaçlı tesadüfi örnekleme yöntemi ile belirlenmiştir. Amaçlı tesadüfi örnekleme yöntemi ile belirlenen çalışma grubuna ilişkin veriler yarı yapılandırılmış görüşme formu kullanılarak “Google Forms” aracılığıyla toplanmıştır. Görüşme formundan elde edilen veriler, içerik analizi yöntemi kullanılarak analiz edilerek elde edilmiştir. Elde edilen bulgular yorumlanmış ve sonuçlara ilişkin öneriler sunulmuştur.
Araştırmanın sonucunda; repertuvarda bulunan, dört keman için orijinal/aranje edilmiş eserlerin toplam sayısı göz önünde bulundurulduğunda, katılımcıların yeteri kadar eser tanımadıkları ve tanıdıkları eserleri öğrencilerinin eğitiminde kullanan katılımcı sayısının da beklenenden az olduğu tespit edilmiştir. Sonuçlar doğrultusunda; Türk Müzik Kültürü’ne ve keman eğitimine katkı sağlayacak, eğitim niteliğinin yükseltilmesi amaçlı 4 Keman için Klasik Batı Müziği ve Türk Müziği'ne ilişkin basit, orta ve yüksek seviyede, küçük ve büyük ölçekli besteler veya düzenlemeler yapılarak kitaplaştırılması ve yeni eserlerin repertuvara eklenerek tanıtılmasına ilişkin konserler verilmesi önerilmiştir.