bluuebunny/crossref_metadata_2025_split huggingface dataset:
Truncated Affine Rozansky–Witten Models as Extended TQFTs
Authors: Brunner Ilka , Carqueville Nils , Roggenkamp Daniel 
Published: February 2023

AbstractWe construct extended TQFTs associated to Rozansky–Witten models with target manifolds $$T^*\mathbb {C}^n$$

T
∗

C

n

. The starting point of the construction is the 3-category whose objects are such Rozansky–Witten models, and whose morphisms are defects of all codimensions. By truncation, we obtain a (non-semisimple) 2-category $$\mathcal C$$
C
of bulk theories, surface defects, and isomorphism classes of line defects. Through a systematic application of the cobordism hypothesis we construct a unique extended oriented 2-dimensional TQFT valued in $$\mathcal C$$
C
for every affine Rozansky–Witten model. By evaluating this TQFT on closed surfaces we obtain the infinite-dimensional state spaces (graded by flavour and R-charges) of the initial 3-dimensional theory. Furthermore, we explicitly compute the commutative Frobenius algebras that classify the restrictions of the extended theories to circles and bordisms between them.
Dimer–Dimer Correlations at the Rough–Smooth Boundary
Authors: Johansson Kurt , Mason Scott 
Published: February 2023

AbstractThree phases of macroscopic domains have been seen for large but finite periodic dimer models; these are known as the frozen, rough and smooth phases. The transition region between the frozen and rough region has received a lot of attention for the last twenty years and recently work has been underway to understand the rough–smooth transition region in the case of the two-periodic Aztec diamond. We compute uniform asymptotics for dimer–dimer correlations of the two-periodic Aztec diamond when the dimers lie in the rough–smooth transition region. These asymptotics rely on a formula found in Chhita and Johansson (Adv Math 294:37–149, 2016) for the inverse Kasteleyn matrix, they also apply to the infinite square grid dimer model with a variable weighting which interpolates between the rough and smooth phase (Kenyon et al. Ann Math (2) 163(3):1019–1056, 2006). In particular, we find that distant dimers initially decay exponentially when the magnetic coordinates are very close to the bounded complementary component of the associated amoebae, they then transition to a power law decay once far enough apart.
Nash Equilibria Strategies and Equivalent Single-Objective Optimization Problems. The Case of Linear Partial Differential Equations
Authors: Ramos Angel Manuel 
Published: February 2023

AbstractIn this paper we study the existence and uniqueness of Nash equilibria (solution to competition-wise problems, with several controls trying to reach possibly different goals) associated to linear partial differential equations and show that, in some cases, they are also the solution of suitable single-objective optimization problems (i.e. cooperative-wise problems, where all the controls cooperate to reach a common goal). We use cost functions associated with a particular linear parabolic partial differential equation and distributed controls, but the results are also valid for more general linear differential equations (including elliptic and hyperbolic cases) and controls (e.g. boundary controls, initial value controls,...).
Slurry Tales: Newspaper Coverage of Livestock Slurry Reproduces Public Discourse on Agriculture in Germany
Authors: Artner-Nehls Astrid , Uthes Sandra 
Published: February 2023

AbstractThe rapid transition of livestock husbandry in the 20th century involved a broad adoption of slurry-based livestock housing systems that resulted in farm economic benefits, but also in societal debate related to the environment and animal welfare. In this article, we apply the method of topic modeling to four major German newspapers to identify thematic emphases and changes in coverage around “slurry”. We considered more than 2300 articles published between 1971 and 2020. Our results show that reporting encompasses economic, environmental, and social topics in which slurry is represented mostly critically (“poisonous substance”), occasionally neutrally (“scent of countryside”), or rarely positively (“input for the bioeconomy”). Three meta-themes overarch the majority of issues and reflect public discourse on agriculture: (i) the dichotomy of agricultural industrialization and family farming; (ii) contrasting actualities of factory farming and animal welfare; and (iii) the responsibility of policy for the emergence, existence and solution of livestock and slurry-related problems. A more balanced recognition of mutual values and constraints by the media could contribute to a discursive reconciliation of public and private interests.
Delay of laminar–turbulent transition by counter-rotating cylindrical roughness elements in a laminar flat plate boundary layer
Authors: Römer Tristan M. , Schulz Kai A. , Wu Yongxiang , Wenzel Christoph , Rist Ulrich 
Published: February 2023

Abstract
Delaying laminar–turbulent transition in boundary layers is of great interest since the skin-friction coefficient can be reduced by up to one order of magnitude. In this experimental research, it is shown that counter-rotating cylindrical roughness elements are able to delay transition under realistic flow conditions. Evidence is given by the intermittency, evaluated from hot-film measurements in a laminar water channel. An increase in rotation speed results in a delay of transition of up to $${6.5}{\%}$$

6.5

%

in the center of the plate. This trend can be explained by the streaks amplified by the rotating cylinders, resulting in a damping of the fluctuation amplitude in the boundary layer. The advantage of this method is that the transition delay can be actively controlled with conventional cylindrical roughness elements.

Graphical abstract
Distal shunt placement in pediatric ventriculoperitoneal shunt surgery: an international survey of practice
Authors: Ruf Linus , Greuter Ladina , Guzman Raphael , Soleman Jehuda 
Published: February 2023

Abstract
Objective
Ventriculoperitoneal shunt (VPS) surgery is a common treatment for hydrocephalus in children and adults, making it one of the most common procedures in neurosurgery. Children being treated with a VPS often require several revisions during their lifetime with a lifetime revision rate of up to 80%. Several different techniques exist for inserting the distal catheter, while mini-laparotomy, trocar, or laparoscopy is traditionally used. As opposed to adults, only few studies exist, comparing the outcome of the different distal catheter placement techniques in children. This international survey aims to investigate the current daily practice concerning distal shunt placement techniques in children.

Material and methods
An online questionnaire investigating the different techniques used to place the distal catheter in pediatric VPS surgery was distributed internationally. All results were analyzed using descriptive and comparative statistics.

Results
A total of 139 responses were obtained. Mini-laparotomy was reported to be the most frequently used technique (n = 104, 74.8%) for distal shunt placement in children, while laparoscopic or trocar-assisted placements were only used by 3.6% (n = 5) and 21.6% (n = 30) of all respondents, respectively. Over half (n = 75, 54.0%) of all respondents do not believe that laparoscopic placement improves the outcome.

Conclusion
This international survey shows that mini-laparotomy is the most frequently used technique for distal VPS placement in children all over the world. Further randomized trials are needed to elucidate this matter.
Syringomatous dermatitis: a myth or an existing entity?
Authors: Hassab-El-Naby Hussein M. M. , Nouh Ahmed H. 
Published: February 2023

AbstractSyringoma is rare disease that in classical variant occurs mainly on lower eyelids. In previously published researches, there is increasing evidence that eruptive syringomas must be discussed as an inflammatory dermal reaction pattern. And there was a proposal to change a name from eruptive syringoma to reactive syringomatous proliferation in appropriate cases. We conduct retrospective study on histopathological archived material to study the histopathological findings in cases of eruptive syringomas and correlate it with hypothesis that eruptive syringomas is not true adnexal neoplasms “de novo” but a hyperplastic response of the acrosyringium to an inflammatory process.According to obtained data and literature correlation, we can conclude that there is apparent diversity in eruptive syringomas. Part of cases can be calculated as neoplastic lesions arising “de novo,” and another part as reactive syringomatous proliferation due to preceding cutaneous inflammatory process. Thus, term “eruptive syringoma” may be changed in appropriate cases to a “reactive syringomatous proliferation.”Clinical variants of eruptive syringoma with evidence of underlying inflammatory process may be more responsive on types of treatments used for inflammatory disorders. Thus, more global clinicopathological correlative researches should be conducted and classification with terminology should be appropriately changed.
CIN2 + detection in high-risk HPV patients with no or minor cervical cytologic abnormalities: a clinical approach validated by machine learning
Authors: Wittenborn Julia , Kupec Tomas , Iborra Séverine , Najjari Laila , Kennes Lieven N. , Stickeler Elmar 
Published: February 2023

Abstract
Purpose
To evaluate the feasibility and diagnostic value of the combination of colposcopy, cytology and hrHPV (high-risk human papilloma virus) PCR (polymerase chain reaction) testing in patients with no or minor cytologic abnormalities and HPV high risk infection and to find the best predictors for the presence of CIN2 + in this patient collective.

Methods
Three hundred and thirty-four hrHPV patients with normal cytology or minor cytologic abnormalities who had a colposcopic examination at the center of colposcopy at the university hospital Aachen in 2021 were enrolled in this retrospective cohort analysis. Multivariate logistic regression and a machine-learning technique (random forests, leave-one-out analysis) were used.

Results
The overall risk for CIN2 + in hrHPV-positive patients with normal cytology was 7.7% (N = 18) (5% for CIN3 +), 18% (N = 16) (10.1% for CIN3 +) in patients with PAP IIp (ASC-US) and 62.5% (N = 5) (25% for CIN3 +) in patients with PAP IIg (AGC). Variables that show a statistically significant influence for the CIN-status are ‘major change’ as the result of colposcopy, transformation zone type T1, PAP IIg upon referral (AGC) and hrHPV category 1a (HPV 16/18) detection. Using machine learning (random forests) techniques, the main influencing variables were confirmed. A monotonously decreasing risk for CIN2 + from hrHPV category 1a to 3 (in accordance to the IACR guidelines) was found.

Conclusion
In the collective of hrHPV patients with no or minor cytologic abnormalities, the result of colposcopy and HPV PCR status are key predictors for the detection of CIN2 + with a monotonously decreasing risk for CIN2 + from hrHPV category 1a to 3.
Skeletal injuries after cesarean section — a rare differential diagnosis of child abuse
Authors: Küppers L. , Schaffer C. , Helbig M. , Ritz-Timme S. 
Published: February 2023

AbstractBirth-related fractures are an important differential diagnosis of child abuse in early infancy. While fractures associated to vaginal deliveries are well known, cesarean section is not necessarily known to cause such injuries. Nevertheless neonatal fractures have been described after cesarean sections. To give an overview over the frequency and typical locations of such fractures, the appearance of symptoms and the timespan until diagnosis, a literature research was conducted via Google scholar and Pubmed, using the key words “cesarean section” and “fractures”. Birth-related fractures after cesarean sections are rare but can occur, with the long bones being particularly affected. Therefore, birth injuries should always be considered in the forensic medical assessment of fractures in early infancy, even after cesarean section. To enable a differentiation between birth trauma and physical abuse, birth and operation records should be checked for surgical manoeuvres, possible difficulties during the procedure or other risk factors. Birth-related fractures are usually detected early; in rare cases, the diagnosis is made only weeks after birth.
Integrated care for children living with complex care needs: an evolutionary concept analysis
Authors: Cassidy Lorna , Quirke Mary Brigid , Alexander Denise , Greene Jo , Hill Katie , Connolly Michael , Brenner Maria 
Published: February 2023

AbstractChildren with complex care needs (CCNs) are in need of improved access to healthcare services, communication, and support from healthcare professionals to ensure high-quality care is delivered to meet their needs. Integrated care is viewed as a key component of care delivery for children with CCNs, as it promotes the integration of healthcare systems to provide family and child-centred care across the entire health spectrum. There are many definitions and frameworks that support integrated care, but there is a lack of conceptual clarity around the term. Furthermore, it is often unclear how integrated care can be delivered to children with CCNs, therefore reinforcing the need for further clarification on how to define integrated care. An evolutionary concept analysis was conducted to clarify how integrated care for children with CCNs is defined within current literature. We found that integrated care for children with CCNs refers to highly specialised individualised care within or across services, that is co-produced by interdisciplinary teams, families, and children, supported by digital health technologies. Conclusion: Given the variation in terms of study design, outcomes, and patient populations this paper highlights the need for further research into methods to measure integrated care.

What is Known:

• Children with complex care needs require long-term care, and are in need of improved services, communication, and information from healthcare professionals to provide them with the ongoing support they need to manage their condition.

• Integrated care is a key component in healthcare delivery for children with complex care needs as it has the potential to improve access to family-centred care across the entire health spectrum.

What is New:

• Integrated care for children with CCNs refers to highly specialised individualised care within or across services, that is co-produced by interdisciplinary teams, families, and children, supported by digital health technologies.

• There is a need for the development of measurement tools to effectively assess integrated care within practice.
Humour interventions for patients in palliative care—a randomized controlled trial
Authors: Linge-Dahl Lisa , Kreuz Rainer , Stoffelen Mieke , Heintz Sonja , Ruch Willibald , von Hirschhausen Eckart , Radbruch Lukas 
Published: February 2023

Abstract
Purpose
The effect of humour on end-of-life patients could be beneficial and is worth investigating. However, data on humour interventions for patients in palliative care are scarce. This study evaluated the effects of a humour intervention in a palliative care setting.

Methods
A two-step intervention was developed based on the humour habits programme by McGhee. Patients were assisted to remember funny episodes from their past and recognize humorous aspects of the present and encouraged to produce humour. The intervention and control group completed questionnaires on life satisfaction, cheerfulness, symptom burden, and perceived stress and if possible gave saliva samples to investigate oxytocin levels. The study was a randomized controlled monocentre study on patients treated in a palliative care ward. Participants had to be conscious and alert enough to complete data collection. Overall, 55 patients were included and randomized to the intervention or control group.

Results
Parameters in the control group did not change significantly. In the intervention group, seriousness, bad mood, and stress were reduced. Cheerfulness increased significantly after the intervention. However, the methodologically complex intervention setting was too exhausting for the majority of patients.

Conclusion
Patients who were able to participate benefited from the effects of the intervention on multiple levels. For future research simple interventions, biomarkers for well-being and assessments by staff or proxies are needed to include patients with reduced cognitive and physical performance status at the end of their lives.

Trial registration
DRKS00028978 German Registry of Clinical Studies.
Aggregation Properties of Triton X-100 in a Mixture of Ordinary and Heavy Water
Authors: Arkhipov Victor P. , Arkhipov Ruslan V. , Kuzina Natalia , Petrova Ekaterina V. , Filippov Andrei 
Published: February 2023

AbstractThe dynamic and aggregation properties of Triton X-100 in a mixture of ordinary and heavy water in a wide temperature range from room temperature to the cloud point and above were studied. The ratio of ordinary and heavy water was calculated in such a way as to ensure equal densities of Triton X-100 and the water mixture. This made it possible to exclude the effects of sedimentation and study the evolution of Triton X-100 micelles and aggregates, without complication by the effects of spatial phase separation above the cloud point. Self-diffusion coefficients of Triton X-100 molecules were measured by NMR, and the effective hydrodynamic radii of micelles and aggregates were calculated using the Stokes–Einstein relation. The anomalous temperature behavior of the diffusion coefficient of Triton X-100 molecules is explained by changes in the sizes of diffusing objects during their evolution from micelles to dehydrated aggregates below the cloud point and by changes in the sizes of aggregates above the cloud point. The results of the NMR studies are confirmed by data obtained by dynamic light scattering.
Application of the green analytical procedure index to the simultaneous analysis of co-formulated tinidazole and ciprofloxacin in pure form, tablet dosage form, and human plasma using an environmentally friendly micellar high-performance thin-layer chromatographic technology
Authors: Saraya Roshdy E. , Hassan Yasser F. , Eltoukhi Walid E. , Salman Baher I. 
Published: February 2023

AbstractIn individuals with chronic refractory pouchitis and other gastrointestinal disorders, the combination of ciprofloxacin (CIP) and tinidazole (TIN) is beneficial and safe. As a result, a green micellar high-performance thin-layer chromatographic (HPTLC) approach for the immediate analysis of TIN and CIP in pure, spiked human plasma, and co-formulated tablet dosage form has been developed. It is rapid, extremely easy, sensitive, cost-effective, and environmentally friendly. The stationary phase was Merck aluminum HPTLC plates covered with silica gel 60 F254, while the mobile phase was acetone–ethanol–2% watery sodium dodecyl sulfate (3:4:2, V/V). For quantification of both medications, the densitometric scanner was set at 310 nm. For TIN and CIP, this chromatographic separation yielded symmetric, compact peaks with RF values of (0.22 ± 0.009) and (0.42 ± 0.007), respectively. At 310 nm, the separated spots were densitometrically scanned. For TIN and CIP, the detection thresholds were 6.7 ng/band and 25.03 ng/band, respectively. For TIN and CIP, the quantification limits were 20.3 ng/band and 75.25 ng/band, respectively. The approach was validated according to International Council for Harmonisation (ICH) principles and then used to determine the researched medicines in their various pharmaceutical dosage forms, and human plasma yielding an exceptional percent of recovery. In terms of precision and accuracy, the results were in great accordance with the published approach. This method is suitable for the sequential analysis of the two drugs in pure form, tablet dosage forms, and spiked human plasma due to its simplicity, speed, greenness, robustness, and low cost.
Histopathological and immunohistochemical profiles of pulp tissues in immature dogs’ teeth to two recently introduced pulpotomy materials
Authors: Mohamed Mai , Hashem Ahmed Abdel Rahman , Obeid Maram Farouk , Abu-Seida Ashraf 
Published: February 2023

Abstract
Objective
The pulpal response to Hoffmann’s Pulpine mineral (PMIN) and Pulpine NE (PNE) was compared to mineral trioxide aggregate (MTA) when used as pulpotomy materials in immature permanent teeth in dogs.

Materials and methods
Immature premolars were randomly divided according to the observation period into three equal groups (n = 24) (10 days, 30 days, and 90 days) then furtherly subdivided into 3 subgroups according to the material used. Histopathological analysis regarding inflammatory cell infiltration and dentin bridge (DB) formation was done. Immunohistochemical analysis was performed using osteopontin marker.

Results
The results showed that after 90 days, both MTA and PMIN subgroups had 100% complete thick DB without inflammation in 87.5% of the samples, while the PNE subgroup failed to form DB in 37.5% of the samples and 50% of samples showed thin initial DB with heavy inflammation in 62.5% of the samples. There was no significant difference between MTA and PMIN, while there was a statistically significant difference between PNE and the two other subgroups in DB formation and inflammatory cell infiltration (P > 0.05). After 90 days, MTA showed the highest mean value of osteopontin positive fraction area followed by PMIN without statistically significant differences, while the least value was recorded in PNE subgroup with statistically significant difference with the remaining subgroups (P < 0.05).

Conclusion
PMIN is a promising alternative to MTA when used for pulpotomy.

Clinical relevance
Vital pulp therapy in immature teeth can be done using PMIN as an alternative to MTA.