bluuebunny/crossref_metadata_2025_split huggingface dataset:
RL-CoPref: A Reinforcement Learning-based Coordinated Prefetching Controller for Multiple Prefetchers
Authors: Yang Huijing , Fang Juan , Su Xing , Cai Zhi , Wang Yuening 
Published: July 2023

Abstract

Modern processors employ data prefetchers to alleviate the impact of long memory access latency. However, current prefetchers are designed for specific memory access patterns, which perform poorly on mixed applications with multiple memory access patterns. To address these issues, RL-CoPref, a reinforcement learning (RL)-based coordinated prefetching controller for multiple prefetchers, is proposed in this paper. RL-CoPref takes diverse program context information as the input, learns to maximize cumulative rewards, and evaluates prefetch quality based on prefetch hits/misses and memory bandwidth utilization. It can dynamically adjust the prefetch activation and prefetch degree, enabling multiple prefetchers to complement each other on mixed applications. Our extensive evaluation, utilizing the ChampSim simulator, demonstrates that RL-CoPref can effectively adapt to various workloads and system configurations, optimizing prefetch control. On average, RL-CoPref achieves 76.15% prefetch coverage, having 35.50% IPC improvement, outperforming state-of-the-art individual prefetchers by 5.91%−16.54% and outperforming SBP, a state-of-the-art (non-RL) prefetch controller, by 4.64%.
Synaptic Dysfunction in Dystonia: Update From Experimental Models
Authors: El Atiallah Ilham , Bonsi Paola , Tassone Annalisa , Martella Giuseppina , Biella Gerardo , Castagno Antonio N. , Pisani Antonio , Ponterio Giulia 
Published: July 2023

Abstract:
Dystonia, the third most common movement disorder, refers to a heterogeneous group of
neurological diseases characterized by involuntary, sustained or intermittent muscle contractions resulting
in repetitive twisting movements and abnormal postures. In the last few years, several studies
on animal models helped expand our knowledge of the molecular mechanisms underlying dystonia.
These findings have reinforced the notion that the synaptic alterations found mainly in the basal ganglia
and cerebellum, including the abnormal neurotransmitters signalling, receptor trafficking and synaptic
plasticity, are a common hallmark of different forms of dystonia. In this review, we focus on the
major contribution provided by rodent models of DYT-TOR1A, DYT-THAP1, DYT-GNAL, DYT/
PARK-GCH1, DYT/PARK-TH and DYT-SGCE dystonia, which reveal that an abnormal motor network
and synaptic dysfunction represent key elements in the pathophysiology of dystonia.
Aktualny stan sektora biogazu rolniczego w Polsce na tle krajów Unii Europejskiej
Authors: Powałka Małgorzata , Golisz Ewa , Klepacka Anna , Skudlarski Jacek 
Published: July 2023

Biogazownia rolnicza jest jednym ze sposobów pozyskania energii na bazie odnawialnych źródeł energii (OZE). Produkcja energii pochodząca z biogazu rolniczego umożliwia wypełnienie przez Polskę nałożonych Narodowych Celów Wskaźnikowych oraz postanowień Pakietu Klimatyczno-Energetycznego. Założenia te, zakładają wzrost udziału odnawialnych źródeł energii w finalnym zużyciu energii do 15%, a w rynku paliw transportowych do 2020 roku do 10%. Rynek biogazu w Polsce znajduje się w fazie wzrostu. Na tle Unii Europejskiej zajmujemy 14 miejsce, pomimo szerokiego zaplecza surowcowego do produkcji biogazu rolniczego. W kraju w 2013 r. funkcjonują 32 biogazownie rolnicze, o łącznej wydajności instalacji do produkcji biogazu 130,33 mln m3. W większości są to przedsiębiorstwa o zainstalowanej mocy elektrycznej powyżej 1 MWe.. Biogaz cieszy się silnym wsparciem krajów Unii Europejskiej, natomiast stan rozwoju technicznego istniejących biogazowni jest zróżnicowany. Największą produkcję biogazu odnotowują Niemcy, Włochy i Austria.
Legal Consequences on Sirri Marriage Performers Without the Permission of the First Wife: Perspective of Islamic Law and Positive Law
Authors: Dodoteng Harisman , Abidin Abidin , Musyahidah Sitti 
Published: July 2023

The aim of this study is to examine the existence of sirri marriages occasionally. Some people even do it without the first wife's permission, resulting in losses for the perpetrators even though the law has determined that marriage must be brought before the official marriage registrar to be registered. On this issue, the researchers focused on investigating the legal consequences for sirri marriage perpetrators without the first wife's permission and the perspective of Islamic law and positive law for sirri marriage perpetrators without the first wife's consent. The provisions for sirri marriage in Islamic law are not found in the Al-Quran and Hadith. Sirri marriage can be made a criminal act in Islamic law, but the provisions fall into jarimah ta'zir. The ta'zir punishment is not directly found in the Al-Quran and Hadith, this type of punishment becomes the judge's or local government's competence. Meanwhile, according to the positive law of sirri marriages that do not comply with or follow the legal procedures for marriage or without asking for the first wife's permission, the marriage can be punished under Article 279. This type of research used a literature review. The researchers suggest that this university should socialize regarding this matter, and registration of marriages must continue to be carried out by the government and the community, in this case, religious leaders.
Environmental Regulation, Environmental Policy Complexity and Technological Innovation Efficiency
Authors: Wu Shao-Hua , Wang He-Qiao , He Miao , Qin Chang 
Published: July 2023

Abstract
Previous studies on the relationship between environmental regulation (ER) and technological innovation efficiency of defence industry (TIE-DI) mainly focus on variability and complexity, while few empirical studies have incorporated environmental flexibility into models, and most of them are based on questionnaires. Therefore, this paper takes environmental regulation and environmental policy complexity (EPC) as the entry point, so as to discuss the feasibility of improving the technological innovation efficiency of China’s defence industry enterprises (CDI), which aims to empirically test the mechanism of ER and EPC on improving the efficiency of applied technological innovation of China’s defence industry enterprises. The research conclusion provides sufficient theoretical basis and empirical support for strengthening the technical innovation efficiency support, standardising the market order and the market leading, establishing the information disclosure mechanism and improving the internal control of industrial enterprises.
The Mechanism and Path of Finance Promoting the Development of Low Carbon Economy
Authors: Li Jin 
Published: July 2023

Abstract
Promoting the development of low-carbon economy (LCEco) to protect the environment is an important dimension to enhance national competitiveness and an effective path to achieve high-quality national development. Therefore, based on the endogenous LCEco growth theory, from the two dimensions of financial technology innovation (FTI) and financial product innovation (FPI), using the spatial measurement method of SLM and SEM, using the panel data of 30 provinces (municipalities and autonomous regions) from 2009 to 2021, this paper deeply explores the impact of FTI and FPI on the development of LCEco. The results show that: FTI and FPI have synergistic effect and positive spatial spillover effect on the LCEco, whose elastic coefficients for them are respectively (–0.125, p < 0.05; –0.084, p < 0.05). Different regions have obvious heterogeneous effects on the FTI, FPI and LCEco, whose elastic coefficients for them are (0.318, p < 0.05; 0.332, p < 0.05). The conclusion not only provides empirical support for the endogenous LCEco growth theory, but also provides effective evidence for the high-quality development path of China’s LCEco.
Trends in Development of Military Vehicles Capabilities Based on Advanced Technologies
Authors: Giurgiu Tiberiu , Virca Ioan , Grigoraș Constantin , Năstăsescu Vasile 
Published: July 2023

Abstract
This paper presents the challenges and perspectives regarding the technologization of military vehicles designed to be used in combat operations or in combat support. The technological progress registered in the production of batteries for the commercial automotive field has generated more and more interest in the hybridization or electrification of military vehicles, but also in the utilization of UGVs on the battlefield. In terms of survivability, either discussing about tanks, infantry fighting vehicles, armoured personnel carriers, or light tactical vehicles, in addition to the armor protection offered to the crew, the emphasis is increasingly on the implementation of active protection systems designed to remove or diminish the effects of enemy strikes. Moreover, as UAVs are more and more present in combat operations, the concept of 360 degrees of protection of vehicles has changed now to a hemispherical need of protection, considering the highly effective threats from above. Another actual trend to be considered is the multi-platform concept with distributed capabilities rather than all-in-one platforms, introducing the collaborative combat approach. Nevertheless, considering the complexity of these advanced systems, their high costs when acquiring or maintaining them, and their impact on logistic support, the implementation of such technologies in military vehicles is not that accelerated.
CORROSION RESISTANCE OF POLYMER-CONTAINING COATINGS OF PROCESSING EQUIPMENT AND PIPELINES
Authors: Голубев А.В. , Лузгина А.С. , Ворончихин В.Д. 
Published: July 2023

В статье рассмотрены проблемы эксплуатации трубопроводов и аппаратов, работающих в контакте с агрессивными средами, режимы их эксплуатации, основные виды коррозионного разрушения покрытий и базовые материалы, используемые для защиты от коррозионного разрушения. Проведена оценка агрессивных факторов, воздействующих на технологические аппараты и трубопроводы в условиях промышленных предприятий. Сформулированы основополагающие требования к выбору защитного антикоррозионного покрытия.
The article deals with the problems of operation of pipelines and apparatuses operating in contact with aggressive media, their operating modes, the main types of corrosion damage to coatings and the basic materials used to protect against corrosion damage. The assessment of aggressive factors affecting technological apparatuses and pipelines in the conditions of industrial enterprises was carried out. The fundamental requirements for the choice of a protective anti-corrosion coating are formulated.
A wearable group-synchronized EEG system for multi-subject brain–computer interfaces
Authors: Huang Yong , Huan Yuxiang , Zou Zhuo , Pei Weihua , Gao Xiaorong , Wang Yijun , Zheng Lirong 
Published: July 2023

ObjectiveThe multi-subject brain–computer interface (mBCI) is becoming a key tool for the analysis of group behaviors. It is necessary to adopt a neural recording system for collaborative brain signal acquisition, which is usually in the form of a fixed wire.ApproachIn this study, we designed a wireless group-synchronized neural recording system that supports real-time mBCI and event-related potential (ERP) analysis. This system uses a wireless synchronizer to broadcast events to multiple wearable EEG amplifiers. The simultaneously received broadcast signals are marked in data packets to achieve real-time event correlation analysis of multiple targets in a group.Main resultsTo evaluate the performance of the proposed real-time group-synchronized neural recording system, we conducted collaborative signal sampling on 10 wireless mBCI devices. The average signal correlation reached 99.8%, the amplitude of average noise was 0.87 μV, and the average common mode rejection ratio (CMRR) reached 109.02 dB. The minimum synchronization error is 237 μs. We also tested the system in real-time processing of the steady-state visual-evoked potential (SSVEP) ranging from 8 to 15.8 Hz. Under 40 target stimulators, with 2 s data length, the average information transfer rate (ITR) reached 150 ± 20 bits/min, and the highest reached 260 bits/min, which was comparable to the marketing leading EEG system (the average: 150 ± 15 bits/min; the highest: 280 bits/min). The accuracy of target recognition in 2 s was 98%, similar to that of the Synamps2 (99%), but a higher signal-to-noise ratio (SNR) of 5.08 dB was achieved. We designed a group EEG cognitive experiment; to verify, this system can be used in noisy settings.SignificanceThe evaluation results revealed that the proposed real-time group-synchronized neural recording system is a high-performance tool for real-time mBCI research. It is an enabler for a wide range of future applications in collaborative intelligence, cognitive neurology, and rehabilitation.
Mutant HTT does not affect glial development but impairs myelination in the early disease stage
Authors: Yang Sitong , Ma Jingjing , Zhang Han , Chen Laiqiang , Li Yuxuan , Pan Mingtian , Zhu Hongcheng , Liang Jun , He Dajian , Li Shihua , Li Xiao-Jiang , Guo Xiangyu 
Published: July 2023

IntroductionHuntington’s disease (HD) is caused by expanded CAG repeats in the huntingtin gene (HTT) and is characterized by late-onset neurodegeneration that primarily affects the striatum. Several studies have shown that mutant HTT can also affect neuronal development, contributing to the late-onset neurodegeneration. However, it is currently unclear whether mutant HTT impairs the development of glial cells, which is important for understanding whether mutant HTT affects glial cells during early brain development.MethodsUsing HD knock-in mice that express full-length mutant HTT with a 140 glutamine repeat at the endogenous level, we analyzed the numbers of astrocytes and oligodendrocytes from postnatal day 1 to 3 months of age via Western blotting and immunocytochemistry. We also performed electron microscopy, RNAseq analysis, and quantitative RT-PCR.ResultsThe numbers of astrocytes and oligodendrocytes were not significantly altered in postnatal HD KI mice compared to wild type (WT) mice. Consistently, glial protein expression levels were not significantly different between HD KI and WT mice. However, at 3 months of age, myelin protein expression was reduced in HD KI mice, as evidenced by Western blotting and immunocytochemical results. Electron microscopy revealed a slight but significant reduction in myelin thickness of axons in the HD KI mouse brain at 3 months of age. RNAseq analysis did not show significant reductions in myelin-related genes in postnatal HD KI mice.ConclusionThese data suggest that cytoplasmic mutant HTT, rather than nuclear mutant HTT, mediates myelination defects in the early stages of the disease without impacting the differentiation and maturation of glial cells.
Bevacizumab-loaded CalliSpheres beads: in vitro loading, release profiles and application in rabbit liver VX2 tumor model
Authors: Ren Kewei , Li Yahua , Zhou Zihe , Wu Kunpeng , Wang Jianan , Yao Jianning , Li Yifan , Ge Xiaoyong , Li Xiao , Li Zhen , Li Zongming , Han Xinwei 
Published: July 2023

BackgroundBevacizumab loaded drug-eluting beads have the potential to reduce TACE related VEGF expression. The purpose of this study was to investigate the in vitro loading, and release profiles of bevacizumab (BEV) loaded on Callispheres beads (CB) and its application in rabbit liver VX2 tumor model.MethodsCB with sizes of 100-300 um and 300-500 um were divided into 5 groups, respectively. BEV with different content was prepared for CB loading, releasing and detected in the solution at different time points. The diameters of CB in each group were measured under a light microscope to calculate the shrinkage rate. The rabbit with VX2 liver model were divided into control group, CB-TACE group, CB-TACE+BEV group, and BEV group. The data of blood test, CT image, HE and IHC staining were compared and analyzed.ResultsThe shrinkage rate of the 100-300 um CB was 2.6-7.2%, while the 300-500 um CB was 0.2-7.1%. The BEV-loaded CB (BEV-CB) has a burst release during the first hour and following gradually released with time. The release profiles of 100-300 um CB reach 34% in 24 hours, while the 300-500 um CB to 25.8%. BEV-CB with sizes of 100-300 um was chosen to perform transcatheter arterial chemoembolization (TACE). The results showed that BEV-CB-TACE not only gradually increased the content of BEV in serum and organ tissue but also reduced the level of VEGF in serum. Pathological results suggested that the expression of HIF-1 was elevated while VEGF and MVD decreased when compared to the other groups.ConclusionIn conclusion, this study confirms that Callispheres beads could efficiency loaded BEV. BEV-CB-TACE has a good safety and effectiveness, and its application could reduce the level of VEGF-A in serum in the treatment of VX2 tumors.
Online revision process in clause-boundary garden-path sentences
Authors: Fujita Hiroki 
Published: July 2023

AbstractA long-standing question in sentence processing research concerns the online parsing process in clause-boundary garden-path sentences, such as After Mary dressed John bathed. In this sentence, “John” must be parsed as the matrix subject DP but can be locally analysed as the object of the embedded verb. There is considerable evidence that the parser misanalyses these garden-path sentences. However, the controversy lies in whether the parser revises them during the online parsing process. The present study investigated this revision process through two self-paced reading experiments utilising grammatical constraints on reflexives and subject or object relative clauses embedded within the locally ambiguous DP. The results provided evidence of revision when a subject relative clause was embedded but not when an object relative clause was embedded. These findings suggest that the parser assigns grammatical structures that correspond to input strings during the revision of clause-boundary ambiguities but that object relative clauses affect the online revision process.
Trypanosoma brucei Invariant Surface gp65 Inhibits the Alternative Pathway of Complement by Accelerating C3b Degradation
Authors: Lorentzen Josefine , Olesen Heidi G , Hansen Annette G , Thiel Steffen , Birkelund Svend , Andersen Christian B F , Andersen Gregers R 
Published: July 2023

Abstract
Trypanosomes are known to activate the complement system on their surface, but they control the cascade in a manner such that the cascade does not progress into the terminal pathway. It was recently reported that the invariant surface glycoprotein ISG65 from Trypanosoma brucei interacts reversibly with complement C3 and its degradation products, but the molecular mechanism by which ISG65 interferes with complement activation remains unknown. In this study, we show that ISG65 does not interfere directly with the assembly or activity of the two C3 convertases. However, ISG65 acts as a potent inhibitor of C3 deposition through the alternative pathway in human and murine serum. Degradation assays demonstrate that ISG65 stimulates the C3b to iC3b converting activity of complement factor I in the presence of the cofactors factor H or complement receptor 1. A structure-based model suggests that ISG65 promotes a C3b conformation susceptible to degradation or directly bridges factor I and C3b without contact with the cofactor. In addition, ISG65 is observed to form a stable ternary complex with the ligand binding domain of complement receptor 3 and iC3b. Our data suggest that ISG65 supports trypanosome complement evasion by accelerating the conversion of C3b to iC3b through a unique mechanism.
The relationship between the work-related strain, psychological flexibility and psychological resilience levels of nurses in the COVID-19 pandemic process
Authors: ORHAN İlksen , YILDIZ Erman , CAN Aylin , DOĞAN YÜKSEKOL Özlem 
Published: July 2023

Purpose:This research was conducted to define relationship between the work-related strain, psychological flexibility, psychological resilience levels of nurses in COVID-19 pandemic.
Material and Methods: This cross-sectional, correlational research was carried out with 359 nurses. The data were collected using a Personal Information Form, the Work-Related Strain Inventory, Acceptance and Action Questionnaire II and Brief Resilience Scale.
Results: The mean work-related strain score of the participants was 41.45±6.51 (min:18, max: 72), while their mean psychological resilience score was 18.57±4.72.
Conclusion: As a result of this study, it was determined that, as psychological resilience levels of nurses increased, their psychological flexibility levels also increased.
The Mediating Effect of Offence-related Feelings of Shame and Guilt on the Relationship Between Sense of Coherence and Emotional Eating in Adult Women
Authors: UZDİL Nurcan , GÜNAYDIN Yurdagül 
Published: July 2023

Purpose: The aim of this study was to examine the mediating effect of offence-related feelings of shame and guilt on the relationship between the sense of coherence and emotional eating in adult women.
Material and Methods: The study was carried out in descriptive-relational design. The population of the research consisted of 543 adult women who met the criteria for inclusion in the research. A Introductory Information Form, Sense of Coherence (SOC), Emotional Eater (EEQ) and Offence-Related Shame and Guilt (ORSGS) were used to collect data.
Results: SOC mean score was 53.35 ± 8.17, EEQ mean score was 10.32 ± 5.90, and ORSGS mean score was 41.10 ± 12.11. It was determined that there was a weak statistically, significant and positive correlation and between EEQ and ORSGS mean scores. It was determined that there was a weak, statistically significant and negative correlation between the SOC and the EEQ mean scores, and a weak, statistically significant and negative correlation between the SOC and the ORSGS mean scores (p
La teoría política de la derecha radical
Authors: Antón-Mellón Joan , Seijo Boado Ismael 
Published: July 2023

This article aims to explain the political theory of the contemporaneous radical right. To do this, their core concepts and how they have been theoretically conceptualized by their cultural referents will be studied. First, it locates radical right within the framework of the far-right, understanding its differences with the extreme right and showing its internal heterogeneity. Then, the cultural referent that have shaped the political theory of the radical right are addressed, specifically four tendencies: the European New Right (ND) of Benoist and Faye (as the main ideological matrix of the radical right), the neotraditionalism of Evola and Dugin, the alt-right of Bannon and the radicalized conservatism of Scruton and Olavo de Carvalho. Finally, the political theory of the radical right is described, marked by a decadentist diagnosis of the society, ethnonationalists objectives and metapolitical and reformist means.
El presente artículo tiene como objetivo explicitar la teoría política de la derecha radical contemporánea. Para ello, se estudiarán sus ideas-fuerza y cómo han sido teóricamente conceptualizada por sus referentes culturales. En primer lugar, se sitúa a la derecha radical dentro del marco de la ultraderecha, entendiendo sus diferencias con la extrema derecha y mostrando su heterogeneidad interna. Después, se atienden a los referentes culturales que han configurado la teoría política de la derecha radical, concretamente a cuatro corrientes: la Nueva Derecha Europea (ND) de Benoist y Faye (como principal matriz ideológica de la derecha radical), el neotradicionalismo de Evola y Dugin, la alt-right de Bannon y el conservadurismo radicalizado de Scruton y Olavo de Carvalho. Finalmente, se describe la teoría política de la derecha radical marcada por un diagnóstico decadentista de la sociedad, unos objetivos etnonacionalistas y unos medios metapolíticos y reformistas.