bluuebunny/crossref_metadata_2025_split huggingface dataset:
ПЕРСПЕКТИВИ ВИКОРИСТАННЯ ЕНЕРГІЇ ОРГАНІЗМУ ДЛЯ ЕНЕРГОЗАБЕЗПЕЧЕННЯ МЕДИЧНИХ ПРИЛАДІВ
Authors: Фелді Діана , Козяр Василь 
Published: July 2023

Для енергозабезпечення дозуючих, моніторних, стимулюючих медичних приладів, особливо тих, які імплантуються, пропонується використовувати електроенергію, отриману від людського організму. Електрика може бути отримана в результаті перетворень інших видів енергії, які притаманні тілу людини: механічної (кінетичної), теплової, енергії окисно-відновлюваних біохімічних реакцій. Завдяки успіхам нанотехнологій з’являється більше можливостей для прогресу в цьому напрямку. З практичної точки зору, використання механічної енергії є найбільш перспективним. Рухи кінцівок або інших частин тіла без додаткового навантаження, навіть несвідомо, здатні забезпечити накопичення енергії, достатньої для медичних потреб. Генерація тілом теплової енергії є більш стабільною, порівняно із механічними рухами. Тому очікується, що отримання електричної енергії за рахунок конвертації тепла людини з використанням, наприклад, ефекту Зеєбека, буде мати певні переваги в плані гарантованості та надійності. Існує великий ряд практичних пропозицій отримання електрики для живлення медичних приладів за рахунок біохімічних реакцій, які відбуваються в організмі людини. Ці роботи поки залишаються на експериментальному рівні в пошуку більшої продуктивності. Теоретично, оптимальним є пряме, без перетворень, споживання електрики, яка реєструється при функціонуванні органів. Але при даному рівні наукового розвитку це практично неможливо.
Analisis Faktor-Faktor yang Menjelaskan Pengimplementasian Nilai-Nilai Utama (Corevalues) AKHLAK pada Karyawan di PT TASPEN (Persero)
Authors: Yekti Widyaningsih  
Published: July 2023

The development of the global economy is currently entering the era of Industry 4.0. Industry 4.0 cannot be faced only with technological development, but must involve social dynamics in it. Every company and agency must create a strategy in dealing with this era, including Badan Usaha Milik Negara (BUMN) by establishing main values that become the reference for the behavior of all human resources in BUMN. These corevalues consist of Trustworthy, Competent, Harmonious, Loyal, Adaptive, and Collaborative (AKHLAK). In practice, AKHLAK has not been implemented properly, even though the corevalues of AKHLAK need to be implemented by all human resources in BUMN. This thesis examines the significant factors explaining the implementation of AKHLAK corevalues on PT TASPEN (Persero) employees and to examine the profile of employees who have implementation corevalues high and low are based on significant factors. The factors used in this study are work motivation, work environment, employee welfare, socialization, employee commitment, religiosity, work stress, age, gender, education level, and years of service. The methods used in solving this research problem are the Partial Least Square (PLS) method and the Classification and Regression Tree (CART) method. The data used is primary data of 209 PT TASPEN (Persero) employees taken using purposive sampling. The results showed that work motivation, socialization, religiosity, and education level can significantly explain the implementation of AKHLAK. The profile of employees who have a high level of implementation of AKHLAK are employees with high level of religiosity, high work motivation, for all categories of educational levels, and work stress levels. The profile of employees who have a low level of implementation of AKHLAK are employees who have low religiosity and work motivation.
Penerapan Metode Support Vector Machines (SVM) dan Metode Naïve Bayes Classifier (NBC) dalam Analisis Sentimen Publik terhadap Konsep Child-free di Media Sosial Twitter
Authors: Dania Siregar  , Faroh Ladayya  , Naufal Zhafran Albaqi  , Bintang Mahesa Wardana  
Published: July 2023

Child-free is a concept in which a person chooses not to have children or places and situations that are without the presence of a child. The application of child-free itself is not something new but is commonplace in many developed countries. Along with the rapid flow of information, this child-free concept began to be discussed virally, especially on Indonesian social media, such as Twitter. People’s views on this concept are certainly diverse, some agree and some disagree. Sentiment analysis is the mining of all people’s expressions and views on a phenomenon or product online in the form of text. Through a large sample collection of opinions and expressions, we can capture the voices or views of society, understand the dynamics that are taking place, and even know the extent to which the issue begins to touch aspects of people’s social life. This study aims to conduct sentiment analysis by comparing the performance of two different methods used to classify people’s views in the form of text data crawled tweets from Twitter. The two methods compared are Support Vector Machines (SVM) and Naive Bayes Classifier (NBC). Another purpose of this study is to provide an overview of public sentiment on social media Twitter about the concept of child-free. The results of this study showed that the data experienced an imbalance so to overcome it used SMOTE, SMOTE managed to increase the sensitivity of the prediction of minor data. The classification method that produces better predictions using the F1-weighted average criteria is SMOTE-SVM by reaching 95.639% for training data and 60.45% for testing data. The opinions that support child-free mostly have to do with parents' unpreparedness to take care of children, while opinions that reject child-free think that it is contrary to Islam and child-free decisions will make it difficult for old age because no one takes care of them.
Effectiveness of a screening tool to assess prevention and rehabilitation needs of 45 to 59 years old in primary care – study protocol of a pragmatic randomized controlled trial (PReHa45)
Authors: Burchardi Jennifer Marie , Spyra Karla , Brünger Martin 
Published: July 2023

Abstract
Background: For years it has been stated that the need for prevention and rehabilitation is not always identified early enough. Although many individuals have regular contact with a general practitioner (GP), this access path for applying for a prevention or rehabilitation service has not been fully exploited. The important role of GPs in supporting the intention to apply is highlighted in the research. This study aims to evaluate the effectiveness of the “check-up 45+” to support GPs both in identifying the need for prevention and rehabilitation services and in submitting applications.
Methods: The study is designed as a two-arm, pragmatic 1:1 randomised controlled study (RCT), which will be conducted in about 20 general practices in the German states of Berlin and Brandenburg. Patients (n=1,654) aged from 45 to 59 years will be recruited by medical assistants. In addition to usual care, both study groups will receive a questionnaire covering socio-economic and occupational variables to be filled out immediately in the waiting room. The intervention group passes through the “check-up 45+”. This includes the completion of the “screening 45+” that aims to assess the need for prevention and rehabilitation services. Medical assistants will immediately evaluate this 2-page screening tool. If a need is identified and confirmed by the GP, information and application documents will be handed over. Moreover, the application process for rehabilitation services is simplified. Primary outcome is the proportion of applications for prevention or rehabilitation services financed by the German Pension Insurance. Administrative data will be provided for this purpose. Secondary outcomes include the proportion of approved applications and completed services. In addition, the proportion of persons with a need for prevention or rehabilitation according to the “check-up 45+” will be examined. Semi-structured interviews will be conducted and content-analysed to determine the practicability and acceptance of the “check-up 45+” by the relevant stakeholders.
Discussion: Prevention and rehabilitation need is insufficiently identified and addressed so far. This study will determine the effectiveness and of the “check-up 45+” in primary care.
Trial registration: German Clinical Trials Register (DRKS00028303, 03.03.2022).
Coinfection of dengue and hepatitis A viruses: a rare case report
Authors: Saldaña Christian Alberto Rodriguez , Fiestas-Cordova Jessenia , Saldaña-Flores José Gerardo , Abramonte-Tene Walter David 
Published: July 2023

Abstract

Introduction:Dengue fever and hepatitis A are viral infections that are prevalent in developing countries. Coinfection with both viruses is a rare occurrence and presents a diagnostic challenge due to their overlapping symptoms. Laboratory tests are required to confirm the diagnosis of each infection. We present a case of a young female with dengue and hepatitis A coinfection.Case presentation:A 25-year-old female presented with abdominal pain, vomiting, and jaundice. Laboratory tests revealed leukopenia, elevated liver enzymes, and positive hepatitis A virus antibodies. During hospitalization, the patient was diagnosed with dengue fever through serological testing.Conclusions:Coinfection with dengue fever and hepatitis A is possible and may result in more severe symptoms and complications. Diagnosis requires laboratory testing, and treatment is primarily supportive care. Healthcare providers should consider testing for both viruses in patients with overlapping symptoms.
Earliest human funerary rites in insular Wallacea 15,500 to 14,700 years ago
Authors: Hawkins Stuart , Zetika Gabriella , Kinaston Rebecca , Firmando Yulio , Sari Devi , Suniarti Yuni , Lucas Mary , Roberts Patrick , Reepmeyer Christian , Maloney Tim , Kealy Shimona , Stirling Claudine , Reid Malcolm , Barr David , Kleffmann Torsten , Kumar Abhishek , Yuwono Pratiwi , Litster Mirani , Husni Muhammad , Ririmasse Marlon , Ita Mahirta , Mujabuddawat Muhammad , Harriyadi Harriyadi , O'Connor Sue 
Published: July 2023

Abstract

The insular region of Wallacea has become a focal point for studying early human evolution in island environments. Here we focus on how socioeconomic adaptations, under changing climatic conditions, influenced the belief systems and burial practices of past foragers at Ratu Mali 2, an elevated coastal cave site on the small, impoverished island of Kisar dated to 15.5–3.7 ka. This multidisciplinary study reveals the impressive flexibility of our species in the most marginal of environments by demonstrating extreme marine dietary adaptations as well as engagement with an extensive trade and exchange network across open seas. A male and a female, interred in a single grave at Ratu Mali 2 by 14.7 ka are the oldest known human burials in Wallacea with established funerary rites. These findings enable exploration of how human societies and belief systems adapted to rising sea levels in Wallacea after the Last Glacial Maximum.
TTR-INR guided warfarin adjustment protocol: A strategy to improve time in therapeutic range in patients with atrial fibrillation receiving warfarin
Authors: Kosum Paisit , Siranart Noppachai , Nissaipan Kunathip , Laohapiboolrattana Wattakorn , Sowalertrat Walit , Triamamornwooth Kanittha , Arunphan Rawiwan , Sri Apiradee , Rungpradubvong Voravut 
Published: July 2023

AbstractBackground:Atrial fibrillation (AF) is a causing ischemic stroke. Warfarin remains a viable oral anticoagulant for many patients. Time in therapeutic range (TTR) is still not widely applied in clinical practice.Purpose:To study the association of change of TTR after implementation of TTR-INR guided warfarin adjustment protocol in patients with AF receiving warfarin.Methods:This is a prospective study of patients with AF at warfarin clinic of King Chulalongkorn Memorial Hospital. TTR was calculated by using Rosendaal linear interpolation method at baseline, 6 and 12 months after protocol implementation. Patient characteristics and outcomes (TTR improvement, embolic and bleeding events, and mortality) were collected. McNemar’s Chi-square test and paired t-test were used to evaluate the relationship between protocol implementation and outcomes.Results:A total of 57 patients were primary analyzed (mean age of 72 years, 50% females). The TTR at baseline was 65% (53% of patients had TTR less than 65%). After 12 months of protocol implementation, TTR were significantly improved (80%) (p<0.001). Significant improvement of proportion of patients with TTR ³65% was shown after protocol implementation (from 47% to 88%) (p<0.001). Three patients died during the follow-up. No ischemic or major bleeding events were occurred during the follow-up in the first 12 months.Conclusion:The TTR was significantly improved after 12 months of protocol implementation. This strategy may offer additional value in TTR improvement and good outcomes in patients with AF receiving warfarin.
Landslide Hazard Zonation (LHZ) Mapping of the Doon Valley using Remote Sensing and GIS Techniques
Authors: Mani Ashish , Kumari Maya 
Published: July 2023

Abstract
The occurrence of landslides is a cataclysmic natural hazard that mainly occurs in hilly areas due to factors like earthquakes, cloud burst, extreme rainfall, human pressure, etc. which causes loss of biodiversity, property, and life. Effective and comprehensive landslide risk management is crucial for landslide susceptibility. Utilizing remote sensing and GIS techniques, this work focuses on Landslide Hazard Zonation mapping in the Doon Valley. The SRTM DEM data at 30m resolution and Sentinel-2B data at 10m resolution have been used to perform the remote sensing and GIS operations in Arc GIS Software. Thematic layers such as LULC, Slope, Geology, Soil Type, Elevation, Drainage Density, Vegetation, and Aspect were produced utilizing remote sensing and GIS data. The Weighted Overlay, a multi-criteria analysis method, was applied to assign attribute values to each thematic layer based on their importance, which was then combined to calculate the Landslide Hazard Zone. The findings of this study demonstrate that landslides are more likely to occur near and above the Main Boundary Fault / Thrust. The High to Very High Hazard Zone covers 16.64% of the total area, making landslides occurring more frequently. Additionally, the study found that the Doon Valley rivers' upper segments are more susceptible to landslides than their lower segments. By integrating Remote Sensing and GIS techniques, it is possible to obtain extensive knowledge of regions prone to landslides. This information will be helpful for decision-makers and planners to reduce the impact of landslides in the near future.
Lambertella (Rutstroemiaceae, Helotiales) from Northern Thailand
Authors: Lest Anis Sri , Wedaralalage Thilini Chethana Kandawatte 
Published: July 2023

Abstract

During our excursions for discomycetes from 2019–2021 in forests and plantations in northern Thailand, several Lambertella-like specimens were found. Morphological observation and BLAST sequence data search confirmed that six newly collected specimens belong to Lambertella. Further phylogenetic analysis using maximum likelihood and Bayesian inference analyses based on combined ITS and LSU sequence data and morphological examination coupled with chemical reactions, confirmed six Lambertella species. Lambertella aurantiaca was established as a new geographical record, and the other five specimens, L. fusoidea, L. phanensis, L. sessilis, L. takensis, and L. tectonae were introduced as novel species. The highlight of the current study is to contribute a complete morphological description of Lambertella aurantiaca since its introduction in 1964, emend the morphological criteria for Lambertella sensu stricto, and provide sequence data for all the Lambertella species described in the current study, including the extant species, L. aurantiaca for the first time, which are essential for future studies.
From Voxels to Prognosis: AI-Driven Quantitative Chest CT Analysis Forecasts ICU Requirements in 78 COVID-19 Cases
Authors: Bumm Rudolf , Zaffino Paolo , Lasso Andras , Estépar Raúl San José , Pieper Steven , Wasserthal Jakob , Spadea Maria Francesca , Latshang Tsogyal , Kawel-Böhm Nadine , Wäckerlin Adrian , Werner Raphael , Hässig Gabriela , Furrer Markus , Kikinis Ron 
Published: July 2023

Abstract
Background: The aim of the current study was to investigate the distribution and extent of lung involvement in patients with COVID-19 with AI-supported, automated computer analysis and to assess the relationship between lung involvement and the need for intensive care unit (ICU) admission. A secondary aim was to compare the performance of computer analysis with the judgment of radiological experts.
Methods: A total of 81 patients from an open-source COVID database with confirmed COVID-19 infection were included in the study. Three patients were excluded. Lung involvement was assessed in 78 patients using computed tomography (CT) scans, and the extent of infiltration and collapse was quantified across various lung lobes and regions. The associations between lung involvement and ICU admission were analyzed. Additionally, the computer analysis of COVID-19 involvement was compared against a human rating provided by radiological experts.
Results: The results showed a higher degree of infiltration and collapse in the lower lobes compared to the upper lobes (p < 0.05) No significant difference was detected in the COVID-19-related involvement of the left and right lower lobes. The right middle lobe demonstrated lower involvement compared to the right lower lobes (p < 0.05). When examining the regions, significantly more COVID-19 involvement was found when comparing the posterior vs. the anterior halves of the lungs and the lower vs. the upper half of the lungs. Patients, who required ICU admission during their treatment exhibited significantly higher COVID-19 involvement in their lung parenchyma according to computer analysis, compared to patients who remained in general wards. Patients with more than 40% COVID-19 involvement were almost exclusively treated in intensive care. A high correlation was observed between computer detection of COVID-19 affections and expert rating by radiological experts.
Conclusion: The findings suggest that the extent of lung involvement, particularly in the lower lobes, dorsal lungs, and lower half of the lungs, may be associated with the need for ICU admission in patients with COVID-19. Computer analysis showed a high correlation with expert rating, highlighting its potential utility in clinical settings for assessing lung involvement. This information may help guide clinical decision-making and resource allocation during ongoing or future pandemics. Further studies with larger sample sizes are warranted to validate these findings.
Carbon Footprints of Bank Loans and Economic Activities' Carbon Dioxide Emissions: Insights from Advanced Economics
Authors: Othman Anwar Hasan Abdullah 
Published: July 2023

Abstract

This paper examines the relationship between the intensity of Carbon Footprints of Bank Loans (CFBLs) and CO2 emissions emitted by advanced economies to assess if financial institutions' lending strategies contribute to addressing climate change risk. Using GMM estimator, the study analysed yearly panel data from 12 advanced economies encompassing 44 industries from 2005 to 2018. The findings of the study reveal that the intensity of CFBLs in advanced economies has inverse association with CO2 emissions from most economic activities (nearly 86.36%). This is an indication that banks' lending portfolios strategies in advanced economies are more sustainable, supporting low-carbon transitions and helping in climate change risk mitigation. Nonetheless, banks still need to be more disciplined about environmental protection measures, such as carbon disclosure requirements, carbon risk assessments, and incorporating environmental, social, and governance factors into their lending decisions and practices. These policies can increase transparency, accountability, and promote environmentally friendly lending practices, contributing to the global effort to address climate change.
Solid tumors exploit proton-sensing GPR65 for orchestration of an immunosuppressive tumor microenvironment
Authors: Bopp Tobias , Truong-Andrevici Natalia , Fontaine Jean-Fred , Klein Matthias , Rapp Steffen , Wilson Alicia , Kunz Sebastian , Sprang Maximillian , Mueller Luise , Schmitz Marc , WIld Philipp , Wolf Sebastian , Kindler Thomas , Gaida Matthias , Cipriani Barbara , Grabbe Stephan , Andrade-Navarro Miguel , Schild Hansjoerg , Hughes Stuart , Bohn Toszka 
Published: July 2023

Abstract

Extracellular acidification profoundly influences anti-tumor immunity but the molecular details of this immune evasion mechanism are not well understood. Here we demonstrate that tumor-associated macrophages (TAM) are capable of sensing H+ ions in a G protein-coupled receptor (GPR)65-dependent manner. This sensing induces a functional polarization of TAM towards an anti-inflammatory phenotype and shapes the composition of the tumor microenvironment (TME). Detailed analyses demonstrated that these anti-inflammatory TAM produce chemokines that attract neutrophil-like cells resulting in an immunosuppressive TME. In contrast, incapability of sensing H+ ions via the GPR65 leads to an improved anti-tumor immune response resulting in the rejection of strongly acidic tumors. Correspondingly, we show that a genetic coding variant in the human GPR65 locus results in strong anti-tumor immunity and improved overall survival.