bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Teichmüller space for negatively curved surfaces
Authors: Hitchin Nigel 
Published: December 2022

AbstractWe first describe the action of the fundamental group of a closed surface of variable negative curvature on the oriented geodesics in its universal covering in terms of a naturally defined flat connection whose holonomy lies in the group of Hamiltonian diffeomorphisms of . Consideration of the holonomy necessitates an extension from Riemannian to Finsler metrics. The second part of the paper follows the Higgs bundle approach to flat connections adapted to this infinite‐dimensional group and focuses on a family of metrics, relying on a construction of O. Biquard, which is parametrised by the infinite‐dimensional space of CR functions on the unit circle bundle of a hyperbolic surface. This generates an alternative approach to defining a connection and offers the possibility of this vector space representing a moduli space which generalizes and includes the classical Teichmüller space.
Applications of Zvonkin’s Transform to Stationary Kolmogorov Equations
Authors: Bogachev V. I. , Röckner M. , Shaposhnikov S. V. 
Published: December 2022

Abstract—
In this note we develop a new analytic version of Zvonkin’s transform of the drift coefficient of a stationary Kolmogorov equation and apply this transform to derive the Harnack inequality for nonnegative solutions in the case where the diffusion matrix is not locally Sobolev. We also obtain a generalization of the known theorem of Hasminskii on existence of a probability solution to the stationary Kolmogorov equation.
On the Equivalence of Singular and Ill-Posed Problems: The p-Factor Regularization Method
Authors: Evtushenko Yu. G. , Bednarczuk E. , Prusinska A. , Tret’yakov A. A. 
Published: December 2022

Abstract
The local equivalence of singular and ill-posed problems in a class of sufficiently smooth mappings is shown, which justifies the use of the p-factor regularization method to solve them. The main constructions in p-regularity theory that are necessary for stable solution of approximate problems are described, and estimation theorems for regularizing algorithms are proved.
Joint Modeling of Wave Phenomena by Applying the Grid-Characteristic Method and the Discontinuous Galerkin Method
Authors: Petrov I. B. , Favorskaya A. V. 
Published: December 2022

Abstract
The aim of this work is to develop a hybrid computational method that combines the grid-characteristic method on regular structured grids with the discontinuous Galerkin method on unstructured tetrahedral grids. The proposed method makes it possible to describe integration domains with complex-shaped boundaries and contact boundaries and to calculate seismic fields taking into account the topography of the Earth’s surface, while saving computational resources. This modification of the method in the three-dimensional case has been proposed in this paper for the first time. Examples of using the developed method for calculating elastic wave phenomena arising during seismic prospecting are given. By way of testing, a comparison is made with results produced by the grid-characteristic method on curvilinear structured grids. The proposed hybrid method can be used not only for seismic prospecting, but also for calculating wave phenomena in other objects of complex shape.
Energy level tuning of push-pull porphyrin sensitizer by trifluoromethyl group for dye-sensitized solar cells
Authors: Higashino Tomohiro , Sugiura Kenichi , Namikawa Keigo , Imahori Hiroshi 
Published: December 2022

We have introduced trifluoromethyl groups into meta-positions of two meso-phenyl rings of a push-pull-type porphyrin dye (ZnP-CF[Formula: see text] to modulate the energy levels of the porphyrin dye for dye-sensitized solar cells (DSSCs). The light-harvesting ability of ZnP-CF[Formula: see text] is almost comparable to those of reference porphyrins where the trifluoromethyl groups are replaced with methyl (ZnP-CH[Formula: see text] or tert-butyl groups (YD2). We revealed that the introduction of the electron-withdrawing trifluoromethyl groups is effective to lower the excited-state oxidation potential of the porphyrin (–0.80 V vs NHE), which is consistent with the theoretical calculation. Meanwhile, DSSCs with ZnP-CF[Formula: see text] exhibited a lower power conversion efficiency ([Formula: see text] of 5.95% than DSSCs with ZnP-CH[Formula: see text] ([Formula: see text] = 7.33%) and YD2 ([Formula: see text] = 8.97%) because of the severe aggregation tendency of ZnP-CF[Formula: see text] arising from the trifluoromethyl groups. In addition, the insufficient steric bulkiness of the trifluoromethyl and methyl groups relative to tert-butyl groups would result in the lower short circuit current and open circuit voltage for ZnP-CF[Formula: see text] and ZnP-CH[Formula: see text] due to fast charge recombination between electrons in the conduction band of TiO2 and I[Formula: see text]in the electrolyte solution. Overall, introducing both trifluoromethyl groups and bulky substituents into a porphyrin core would be necessary to boost cell performance.
Are capital markets turning efficient? Need for financial market efficiency index
Authors: Arora Ruchi , Mehra Rishi 
Published: December 2022

Government, regulators, exchanges, banks, and institutions collaborate to develop rules and devote significant time and resources to improving the financial system, with the ultimate goal of creating a more effective market. The statistics on turnover and earnings only show the market’s Quantitative’ growth. The figures do not demonstrate how the market has improved in terms of Quality and Market Efficiency. A robust market structure and long-term growth in any market are only possible when development is based on both qualitative (market efficiency) and quantitative factors (Turnovers and Earnings). Historically, studies and research have laid great emphasis on determining the market’s level of efficiency. However, market efficiency was always checked using staggered time frames and efficiency tests. The need of the hour is a transparent and simple-to-understand tool that can continuously measure market efficiency and has universal applicability. This study proposes a tool for measuring efficiency called the Financial Market Efficiency Index — FMEI. The Index would derive its parameters from the broad market Index of any country to assess and compare market efficiency. The index would not only measure the qualitative growth (Market Efficiency) of any market, but it would also compare the market efficiency of all countries around the world. This would allow stakeholders to make the best decisions for their respective markets.
Comparison of Continuous and Programmed Intermittent Bolus Infusion of 0.2% Ropivacaine after Ultrasound-Guided Continuous Interscalene Brachial Plexus Block in Arthroscopic Shoulder Surgery
Authors: Kim Hye-Jin , Baek Ji-Hye , Park Seyeon , Yoon Ji-Uk , Byeon Gyeong-Jo , Shin Sang-Wook 
Published: December 2022

Background. Despite the clinical effectiveness of the programmed intermittent bolus (PIB) method for epidural analgesia, evidence for this method in continuous interscalene brachial plexus block (CIBPB) is unclear. This study aimed to investigate the pain relief effect after arthroscopic shoulder surgery according to the administration method by comparing the PIB and continuous infusion methods among the administration methods of local anesthetics. Methods. Sixty-four patients aged >19 years scheduled for elective arthroscopic shoulder surgery were enrolled and divided into two groups. Ultrasound-guided CIBPB was performed to control postoperative pain. The infusion pump was programmed so that 0.2% ropivacaine was continuously injected at 1.1 mL/h in group A, whereas in group B, 0.1 mL/h was continuously injected and 4 mL was periodically injected at 4 h intervals. In both groups, a further infusion of 4 mL of 0.2% ropivacaine was administered if the patient requested additional analgesia, and the lockout time was set at 30 min. Postoperative pain quality was assessed using a visual analog scale (VAS), and the incidence of patients requiring additional analgesics, motor blockade using a modified Bromage scale (MBS), and consumed doses of local anesthetic were assessed. Results. The VAS and incidence of rescue analgesics were performed when the patient could communicate voluntarily after admission to the post-anesthetic care unit, and at 24 and 48 h after surgery showed no significant difference between the two groups. The MBS at 24 h after surgery was significantly higher in group B (

p

= 0.038). In the comparison of consumed doses of local anesthetic, group B had a significantly higher bolus injection dose (

p

= 0.047) and frequency of bolus use in the 24 h after surgery (

p

= 0.034). Conclusion. The PIB method in CIBPB after arthroscopic shoulder surgery provided a similar analgesic effect, with a higher bolus injection dose of local anesthetic and increased motor blockade than the continuous infusion method.
Tumor-Associated CD19+CD39− B Regulatory Cells Deregulate Class-Switch Recombination to Suppress Antibody Responses
Authors: Pati Subhadip , Mukherjee Sumon , Dutta Saikat , Guin Aharna , Roy Dia , Bose Sayantan , Paul Silpita , Saha Sudipto , Bhattacharyya Sankar , Datta Pratyush , Chakraborty Jayati , Sarkar Diptendra K. , Sa Gaurisankar 
Published: December 2022

AbstractB cells are an essential component of humoral immunity. Their primary function is to mount antigen-specific antibody responses to eliminate pathogens. Despite an increase in B-cell number, we found that serum-IgG levels were low in patients with breast cancer. To solve this conundrum, we used high-dimensional flow cytometry to analyze the heterogeneity of B-cell populations and identified a tumor-specific CD19+CD24hiCD38hi IL10-producing B regulatory (Breg)–cell subset. Although IL10 is a Breg-cell marker, being an intracellular protein, it is of limited value for Breg-cell isolation. Highly expressed Breg-cell surface proteins CD24 and CD38 also impede the isolation of viable Breg cells. These are hurdles that limit understanding of Breg-cell functions. Our transcriptomic analysis identified, CD39-negativity as an exclusive, sorting-friendly surface marker for tumor-associated Breg cells. We found that the identified CD19+CD39‒IL10+ B-cell population was suppressive in nature as it limited T helper–cell proliferation, type-1 cytokine production, and T effector–cell survival, and augmented CD4+FOXP3+ regulatory T–cell generation. These tumor-associated Breg cells were also found to restrict autologous T follicular helper–cell expansion and IL21 secretion, thereby inhibiting germinal transcript formation and activation-induced cytidine deaminase expression involved in H-chain class-switch recombination (CSR). This isotype-switching abnormality was shown to hinder B-cell differentiation into class-switched memory B cells and subsequent high-affinity antibody-producing plasma B cells, which collectively led to the dampening of IgG-mediated antibody responses in patients with cancer. As low IgG is associated with poor prognosis in patients with cancer, Breg-cell depletion could be a promising future therapy for boosting plasma B cell–mediated antibody responses.
Instruments for Measuring Recovery among Serious Mental Illness: A Systematic Review of Systematic Review
Authors: Thongsalab Jutharat , Yunibhand Jintana , Uthis Penpaktr 
Published: December 2022

Background: Indicators of recovery outcomes are selected by mental health nurses beginning with a commitment to a holistic and client-centered view of recovery. The purpose of the review aimed to bring together the results of previous systematic reviews on instruments for assessing the recovery of people with serious mental illnesses.
Methods: A systematic literature review was carried out using the guidelines of the Joanna Briggs Institute for systematic reviews. A literature search using The ScienceDirect, SpringerLink electronic databases, Google Scholar, and a Google search engine was used. Searching in literature published between January 2010 and December 2020, supplemented by reference tracking and Internet searches. The authors independently reviewed all titles, assessed articles’ eligibility for inclusion, determined a methodological quality score for each included article and extracted relevant data.
Results: Out of 19,724 articles related to the title for potential inclusion in this review, four met the inclusion criteria. The eligibility tools appear to have been studied in various settings and with varied types of patients but are still congruent with SIM. Most importantly, the reviews identified several methodological limitations across the original studies. The lack of a ‘gold standard. This review found twenty-two dimensions in personal recovery instruments and twenty-one in mental health services orientation. Also, many recovery assessment tools are available for the serious mental illness population. However, there is limited evidence about their psychometric properties.
Conclusion: Three instruments were found that could measure the personal recovery of people with serious mental illnesses. Those instruments' psychometric properties and cultural adaptation are recommended for further studies.
The Impact of Tropical Pacific SST Biases on the S2S Forecast Skill over North America in the UFS Global Coupled Model
Authors: Stan Cristiana , Krishnamurthy V. , Bai Hedanqiu , Li Bin , Mehra Avichal , Meixner Jessica , Moorthi Shrinivas , Stefanova Lydia , Wang Jiande , Wang Jun , Worthen Denise , Yang Fanglin 
Published: December 2022

Abstract
The impact of tropical Pacific sea surface temperature (SST) biases on the deterministic skill of the Unified Forecast System (UFS) coupled model Prototype 5 is evaluated during weeks 1–4 of the forecast. The evaluation is limited to the contiguous United States (CONUS) and two seasons: boreal summer (June–September) and winter (December–March). The tropical SST in the UFS model is warmer than in observations and bias patterns show seasonal dependence especially in the central and western Pacific. During boreal summer, the bias is located north of the equator whereas in winter, the bias is located in the Southern Hemisphere. A regression analysis indicates a significant relationship between these SST biases and the biases in the surface temperature and precipitation over the CONUS along with midtroposphere large-scale circulation and North Pacific storm-track activity. The SST biases affect the biases in other fields from week 1 of the forecast and the impact becomes stronger as the lead time increases to week 4. The impact of SST biases on the biases in other fields show a qualitative relationship to the patterns of forecast errors of the fields.
Utility of Screening for Obstructive Sleep Apnea with the Pediatric Sleep Questionnaire (PSQ) in Children with Craniofacial Anomalies
Authors: Solis Roberto N. , Aulakh Sukhkaran S. , Velazquez-Castro Oscar S. , Farber Nicole I. , Olarewaju Adebola M. , Nandalike Kiran , Tollefson Travis T. , Senders Craig W. , Funamura Jamie L. 
Published: December 2022

Objective To determine the accuracy of the Pediatric Sleep Questionnaire (PSQ) as a screening tool for obstructive sleep apnea in children with craniofacial anomalies. Design Retrospective cohort study. Setting Multidisciplinary cleft and craniofacial clinic at a tertiary care center. Patients Children with craniofacial anomalies 2 to ≤18 years of age who both completed a PSQ screen and underwent polysomnography (PSG) without interval surgery. Main outcome measures Sensitivity and specificity of the PSQ in detecting an obstructive apnea-hypopnea index (AHI) ≥ 5 events/hour. Results Fifty children met study criteria, with 66% (n = 33) having an associated syndrome. Mean patient age at time of PSQ was 9.6 + 4.0 years. Overall, 33 (64%) screened positive on the PSQ, while 20 (40%) had an AHI ≥ 5. The sensitivity and specificity for identifying AHI ≥ 5 was 70% and 40%, respectively. With subgroup analysis, the sensitivity and specificity were higher (100% and 50%) in children with non-syndromic palatal clefting but lower (65% and 31%) in children with a syndrome or chromosomal anomaly. There was no correlation detected between PSQ score and AHI severity (p = 0.25). The mean obstructive AHI in the study population was 10.1 ± 22.7 despite 44% (n = 22) undergoing prior adenotonsillectomy. Conclusions The PSQ was less sensitive and specific in detecting an AHI ≥ 5 in children with craniofacial anomalies than in a general population, and particularly poor in for children with syndrome-associated craniofacial conditions. Given the high prevalence of OSA in this patient population, a craniofacial-specific validated screening tool would be beneficial.
Establishment of a Predictive Model for Poor Prognosis of Incomplete Revascularization in Patients with Coronary Heart Disease and Multivessel Disease
Authors: Lian Huan , Zhao Zhuoyan , Ma Kelin , Ding Zhenjiang , Sun Lixian , Zhang Ying 
Published: December 2022

Objective To establish a predictive model for poor prognosis after incomplete revascularization (ICR) in patients with multivessel coronary artery disease (MVD). Methods Clinical data of 757 patients with MVD and ICR after percutaneous coronary intervention (PCI) in the Affiliated Hospital of Chengde Medical University from January 2020 to August 2021 were retrospectively collected. The least absolute shrinkage and selection operator regression method was used to screen variables, and multivariate logistic regression was used to establish a predictive model. An independent cohort was used to validate the model. The C-statistic was used to verify and evaluate the discriminative ability of the model; the calibration curve was drawn, and the decision curve analysis (DCA) was performed to evaluate the calibration degree, the clinical net benefit, and the practicability of the model. Results The predictive factors included female, age, unconjugated bilirubin, uric acid, low-density lipoprotein, hyperglycemia, total occlusion, and severe tortuosity lesion on coronary angiography. The C-statistic of the training and validation sets were 0.628 and 0.745, respectively. The statistical value of the Hosmer–Lemeshow test for the calibration curve of the training and validation sets were 5.27(P = 0.873) and 6.27 (P = 0.792), respectively. DCA showed that the model was clinically applicable when the predicted probability value of major adverse cardiovascular events(MACEs) ranged from 0.07 to 0.68. Conclusions We established a predictive model for poor prognosis after ICR in patients with MVD. The predictive and calibration ability and the clinical net benefit of the predictive model were good, indicating that it can be used as an effective tool for the early prediction of poor prognosis after ICR in patients with MVD.
How brachial access compares to femoral access for invasive cardiac angiography when radial access is not feasible: A meta-analysis
Authors: Mele Marco , Mele Antonietta , Cuculo Andrea , Tricarico Lucia , Liantonio Antonella , Imbrici Paola , Santoro Francesco , Brunetti Natale Daniele 
Published: December 2022

Background: Trans-radial access is considered the best approach for cardiac catheterization. The choice of an alternative access route may be complex and trans-femoral access (TFA) is generally preferred. However, trans-brachial approach (TBA) may represent another feasible alternative. We therefore aimed to compare TBA and TFA in terms of access site bleeding and complications in a meta-analysis study. Methods: We systematically searched principal databases for studies comparing femoral and brachial approach in terms of in-hospital vascular complications in patients undergoing cardiac catheterization (coronary angiography or percutaneous coronary intervention). Results: Five retrospective studies and one randomized study were identified for the meta-analysis; 2756 patients undergoing a TBA and 331.208 patients undergoing a TFA for cardiac catheterization were included in the final study. No significant differences between access routes were found in terms of risk of any vascular complications (relative risk 1.18; 95% CI: 0.91–1.53; p n.s.). Brachial access was associated with a significantly lower risk of access site bleeding (relative risk 0.46; 95% CI 0.24–0.88, p = 0.02). Conclusions: TBA for cardiac catheterization was associated with a lower risk of access site bleeding and a comparable risk of any vascular complications compared with TFA. TBA may be considered a reasonable alternative access route for cardiac catheterization, at least as femoral approach.
Understanding the subjective experiences of memory concern and MCI diagnosis: A scoping review
Authors: Carter Christine , James Tiffeny , Higgs Paul , Cooper Claudia , Rapaport Penny 
Published: December 2022

Introduction Many older people experience memory concerns; a minority receive a diagnosis of Mild Cognitive Impairment (MCI) or Subjective Cognitive decline (SCD). There are concerns that medicalisation of MCI and memory concern may fail to acknowledge subjective experiences. Aim We explore the meaning individuals give to their memory concerns, with or without a diagnosis of MCI and SCD. Method We scoped literature exploring subjective experiences of memory concern, with or without a diagnosis of MCI or SCD. We searched CINAHL, PsycINFO and MEDLINE in March 2020, and updated in Sept 2021.We used (Arksey & O’Malley, 2005) framework to guide our scoping review method and thematic analysis to analyse our findings. Results We screened 12,033 search results reviewing the full texts of 92 papers. We included 24 papers, including a total of 453 participants, the majority of whom were female, from White ethnic majority populations (or from studies where ethnicity was not identified) with high levels of education. In 15 out of 24 studies, 272 participants were diagnosed with MCI. We identified two themes; Making a diagnosis personal and Remembering not to forget. We found that subjective experiences include normative comparison with others of the same age and responses including fear, relief, and acceptance, but culminating in uncertainty. Conclusion Drawing upon sociology, we highlight the subjective experiences of living with memory concerns, SCD and an MCI diagnosis. We identify a gap between the intended purpose of diagnostic labels to bring understanding and certainty and the lived experiences of those ascribed them.