bluuebunny/crossref_metadata_2025_split huggingface dataset:
Natural Eutectic Solvent Mixture of l‐Menthol/Malonic acid (4 : 1) and Its Ibuprofen Solution: Thermal and Physical Characterizations and NMR Studies of Molecular Interaction
Authors: Lázaro‐Rangel Jehovani M. , Sánchez Analilia , Inoue Motomichi , Olivares‐Romero José Luis , Meza‐Gordillo Rocío , Salas‐Reyes Magali , Virués Claudia , Domínguez Zaira 
Published: December 2022

AbstractA eutectic mixture of L‐menthol and malonic acid, Me/MA (4 : 1), was characterized by calorimetry and other physical measurements. The new deep eutectic solvent (m.p. 6 °C) solvates 338 mg of ibuprofen per mL, and the solution is stable in a wide temperature range. Strategies of NMR titration used in supramolecular chemistry were employed to explore binding forces between the eutectic constituents as well as solute‐solvent interaction in ibuprofen solution. Even in acetonitrile, Me4MA is formed through a hydrogen‐bonding network, where the constituents act as hydrogen donors and acceptors at the same time. The estimated association constant is around 30 M−1; the binding forces are enough to build the eutectic mixture at high concentrations. The aggregate Me4MA forms a molecular complex with ibuprofen in acetonitrile as a result of the cooperative effect of the constituents. In addition, van der Waals interactions are operative between ibuprofen and menthol in the saturated IB‐Me/MA (4 : 1) solution.
Bowl‐shaped hollow N‐doped carbon as an electrochemical platform for the highly selective and sensitive electrochemical detection of isoprenaline in pharmaceutical injection
Authors: Zhou Menglin , Su Guoning , Pu Shunhua , Tang Tingfan , Lu Danxia , Cheng Hao , Deng Min , Hu Guangzhi , Liu Xiaoyan 
Published: December 2022

AbstractIn this study, bowl‐shaped N‐doped hollow carbon sphere‐containing mesoporous nanomaterials (BNHC) were used for the ultrasensitive electrochemical detection of isoprenaline (ISOP). The linear ranges of the BNHC‐based sensor were as follows: 0.05 – 15 μM; 15 – 70 μM, with the limit of detection (LOD) of 6.8 nM. And the BNHC‐based electrochemical sensor showed a good current response to ISOP and maintained 95.6 % of the initial current after 30 days of storage. Notably, when the BNHC‐modified sensor was used to detect the actual ISOP injection and urine samples, the sensor exhibited satisfactory recovery.
Spatiotemporal variations of large wood and river channel morphology in a rapidly degraded reach of an intermittent river
Authors: Galia Tomáš , Škarpich Václav , Vardakas Leonidas , Dimitriou Elias , Panagopoulos Yiannis , Spálovský Vilém 
Published: December 2022

AbstractThe links between rapid channel degradation and related large wood (LW) recruitment and storage are still not precisely understood, especially in aquatic systems with high human and natural pressures such as intermittent rivers in the peri‐Mediterranean region. In this study, by using multidisciplinary research (analysis of satellite images time series, detailed field inventory, and simulated hydrological data), we focused on rapid upstream propagation of channel degradation (i.e., incision and consequent channel widening) in an intermittent Mediterranean river (Evrotas River, southern Greece) as a response to short‐term intensive gravel extraction from the active channel and removal of riparian vegetation in the 2013–2016 period. Subsequently, our objective was to link this channel transformation with the spatiotemporal changes of LW storage in the active channel. We found that short‐term and spatially limited human impact, coupled with high flows, allowed rapid upstream progression (~2 km) of erosion processes (approximately twofold widening of the active channel) during the relatively short 2‐year period (2017–2019). This morphological response accelerated LW recruitment through bank erosion and its subsequent storage in the active channel. Incision and channel widening processes were interrupted in the 2019–2021 period due to the prevalence of relatively low, geomorphologically non‐effective flows. However, the storage of LW in the channel continued to increase as a result of the higher trapping efficiency of the widened channel, a delay between tree death and its final uprooting, or by LW recruitment processes not directly related to flood events. We suggest that freshly recruited LW has the potential to accelerate the establishment of a new channel equilibrium and increase channel heterogeneity through its interaction with flows and sediments.
Starch, gallic acid, their inclusion complex and their effects in diabetes and other diseases—A review
Authors: Nag Sayoni , Majumder Suman 
Published: December 2022

AbstractStarch is the most important energy‐providing component of food. It is useful for maintaining the structural and rheological consistency of food, ad thus, in turn, is responsible for maintaining the freshness of food. Polyphenols are present in plant products in huge amounts as secondary metabolites. Gallic acid, one of the potent plant polyphenols, has been reported to have excellent anti‐inflammatory, antioxidative, anticarcinogenic, microbicidal, and antidiabetic properties. Till date, very few articles on the starch–polyphenol inclusion complex are present. Quite a few hypotheses have been proposed as to how the formation of an inclusion complex of starch with polyphenol can slower the digestion or the hydrolysis of starch. The efficient qualities of starch–polyphenol systems, such as reduced starch digestion, lower blood glucose and preserving food freshness, have formed a necessity for investigation in this area. The focus of this review centers on the recent research on starch–polyphenol interactions and starch–gallic acid inclusion complexes in native and extruded food systems, as well as how the production of these complexes can aid in the treatment of diseases, particularly diabetes mellitus.
The impact of strike action on healthcare delivery: A scoping review
Authors: Essex Ryan , Ahmed Salina , Elliott Helen , Lakika Dostin , Mackenzie Laura , Weldon Sharon Marie 
Published: December 2022

AbstractBackgroundStrike action carried out by healthcare workers raises a range of ethical issues. Most fundamentally, as a strike is designed to disrupt, it has the potential to impact patient outcomes and healthcare delivery. This paper synthesises and analyses the empirical literature that details the impact of strike action on healthcare delivery.MethodsA systematic scoping review was utilised to examine the extent, range and nature of research activity. Embase, Medline, CINAHL, Bioethicsline, EconLit and Web of Science were searched, yielding 5644 results. Papers were included if they examined the impact that strike action had on healthcare delivery (i.e., admissions, presentations, waiting time). After screening, 43 papers met inclusion criteria.ResultsNineteen studies explored presentations to emergency or admissions to hospital. Both dropped dramatically when comparing non‐strike to strike periods. Ten studies examined length of stay in hospital and waiting times. No clear relationship was found with strike action, with some studies showing that wait times decreased. Nine studies examined the impact of strike action in facilities that were not on strike, but were impacted by nearby strike action along with the impact that strike action had on treatment seeking. Hospitals dealing with these upstream impacts often saw increase in presentations at hospitals, but results relates to treatment seeking during strike action were mixed.ConclusionStrike action can have a substantial impact on the delivery of healthcare, but this impact is not felt uniformly across services. While many services are disrupted, a number are not, with several studies reporting increased efficiency.
Cascading bankruptcies under simultaneous sectorial shocks: Theory and application to the Tunisian banking sector
Authors: Nabi Mahmoud‐Sami , Fersi Sami 
Published: December 2022

AbstractThis paper proposes a theoretical framework modelling the effect of simultaneous sectorial shocks on the banking system resilience, in presence of overlapping portfolio risk. A sectorial shock decreases the value of banks' assets and solvency. We show that beyond a determined threshold, the regulator (central bank) shall intervene in order to avoid that simultaneous sectorial shocks lead to bankruptcies in a cascading process. The model is simulated in the context of the Tunisian banking system for a variety of extreme macroeconomic conditions (economic recession and inflation). The simulations show that the simultaneous shocks to industry, commerce and real estate sectors might lead to the bankruptcies of one to 10 banks among the 23 Tunisian banks via the cascading contagion channel, in the absence of a prompt and adequate intervention by the regulator.
Does intelligence predict development of investment traits from mid to late adolescence? Evidence from a 3‐year longitudinal study
Authors: Bergold Sebastian , Hufer‐Thamm Anke , Abad Borger Katharina , Luhmann Maike , Steinmayr Ricarda 
Published: December 2022

AbstractIntroductionInvestment theories have claimed reciprocal relations between intelligence and investment traits (i.e., personality traits related to seeking out, and dealing with, cognitive challenges). However, previous research has primarily addressed the effects of investment traits on intellectual development (environmental enrichment hypothesis) and often focused on either childhood or later adulthood. The present study investigated the effects of intelligence on investment traits (environmental success hypothesis) from mid to late adolescence.MethodIn a 3‐year longitudinal survey (2008–2011) covering four measurement occasions, the predictive effects of both fluid and crystallized intelligence on intraindividual change in both the achievement motive (i.e., hope for success and fear of failure) and need for cognition were examined. Overall, 476 adolescents (t1:Mage = 16.43, SD = 0.55; 51.3% girls) from Germany participated.ResultsSecond‐order latent growth models indicated that fluid intelligence predicted a steeper growth in hope for success (β = .40), but was unrelated to change in the other investment traits. Crystallized intelligence had no effects on the investment traits under study.ConclusionsThe results contribute to the research on the bidirectionality of intelligence and investment traits and add to our understanding of personality development from mid to late adolescence. Specifically, they underline the importance of nurturing hope for success especially in individuals with lower intelligence, but also show that support for the environmental success hypothesis seems to be limited to certain investment traits.
Associations Among Hip Structure, Bone Mineral Density, and Strength Vary With External Bone Size in White Women
Authors: Jepsen Karl J , Bigelow Erin MR , Casden Michael A , Goulet Robert W , Kennedy Kathryn , Hertz Samantha , Kadur Chandan , Nolan Bonnie T , Richards‐McCullough Kerry , Merillat Steffenie , Karvonen‐Gutierrez Carrie A , Clines Gregory , Bredbenner Todd L 
Published: December 2022

ABSTRACTBone mineral density (BMD) is heavily relied upon to reflect structural changes affecting hip strength and fracture risk. Strong correlations between BMD and strength are needed to provide confidence that structural changes are reflected in BMD and, in turn, strength. This study investigated how variation in bone structure gives rise to variation in BMD and strength and tested whether these associations differ with external bone size. Cadaveric proximal femurs (n = 30, White women, 36–89+ years) were imaged using nanocomputed tomography (nano‐CT) and loaded in a sideways fall configuration to assess bone strength and brittleness. Bone voxels within the nano‐CT images were projected onto a plane to create pseudo dual‐energy X‐ray absorptiometry (pseudo‐DXA) images consistent with a clinical DXA scan. A validation study using 19 samples confirmed pseudo‐DXA measures correlated significantly with those measured from a commercially available DXA system, including bone mineral content (BMC) (R2 = 0.95), area (R2 = 0.58), and BMD (R2 = 0.92). BMD–strength associations were conducted using multivariate linear regression analyses with the samples divided into narrow and wide groups by pseudo‐DXA area. Nearly 80% of the variation in strength was explained by age, body weight, and pseudo‐DXA BMD for the narrow subgroup. Including additional structural or density distribution information in regression models only modestly improved the correlations. In contrast, age, body weight, and pseudo‐DXA BMD explained only half of the variation in strength for the wide subgroup. Including bone density distribution or structural details did not improve the correlations, but including post‐yield deflection (PYD), a measure of bone material brittleness, did increase the coefficient of determination to more than 70% for the wide subgroup. This outcome suggested material level effects play an important role in the strength of wide femoral necks. Thus, the associations among structure, BMD, and strength differed with external bone size, providing evidence that structure–function relationships may be improved by judiciously sorting study cohorts into subgroups. © 2022 The Authors. JBMR Plus published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research.
Influence of calcium‐based desensitizing toothpastes on the bonding performance of universal adhesive
Authors: Wang Silin , Meng Yuchen , Zhang Yuchen , Huang Fan , Teng Rui , Lu Yi , Li Ang , Sun Junyi , Pei Dandan 
Published: December 2022

AbstractThe study evaluated the effect of calcium‐based desensitizing toothpastes on the dentinal tubule occlusion and its influence on the dentin bond strength of universal adhesive. Mid‐coronal dentin samples were prepared for hypersensitivity model and treated by the following calcium‐based desensitizing toothpastes: no treatment (Control), Clinpro (fTCP), Pro‐Relief (Pro‐Argin), and Repair & Protect (Novamin). Single Bond Universal adhesive was applied in self‐etch or etch‐and‐rinse mode. The dentinal tubule occlusion and adhesion interface were evaluated under scanning electron microscope (SEM). A double‐fluorescence technique was used to examine interfacial permeability under confocal laser scanning microscopy (CLSM). The micro‐tensile bond strength (μTBS) was employed, followed by the fracture interface observation. SEM showed the toothpastes occluded dentinal tubules, and the occlusion exhibited stability against acid and abrasion. Hindered resin infiltration was observed in the adhesion interface after desensitization. CLSM showed more water permeation within or under the adhesion interface in etch‐and‐rinse mode than self‐etch mode. Desensitization decreased the μTBS in self‐etch mode. When using etch‐and‐rinse mode, the desensitized samples presented similar μTBS to the control group. No difference in μTBS was found between the two bonding modes, except for the control group. Calcium‐based desensitizing toothpastes can effectively occlude the exposed dentinal tubules with acid‐resistant and abrasion‐resistant stability. The desensitization reduced the dentin bond strength of the universal adhesive system in self‐etch mode but did not affect the bond strength of etch‐and‐rinse mode.
Comparative anatomical survey of Cyclamen L. (Primulaceae) taxa and their traditional medicinal uses in Turkey
Authors: Zare Golshan , Çilden Emre , Çelemli Ömür Gençay 
Published: December 2022

AbstractThe genus Cyclamen is native to Turkey, where it is represented by 12 perennial tuberous geophytic taxa. In this study, a detailed anatomical description of all Cyclamen taxa found in Turkey is provided for the first time. Tuber, root, petiole, and leaf cross‐sections were stained with Astra blue and safranin, and tuber slides were also stained with sartur. Tubers of these taxa used by local people as a treatment for infertility were separately investigated. Stomatal index values and epidermis cell features of the studied taxa were measured. Indumentum features of the leaves were described for the first time. Petiole and leaf anatomy and particularly stomatal density, size, and index, provided valuable evidence for species identification. Although the anatomical features of these taxa are not sufficient as diagnostic characters, they can be used together with morphological features.
Prognostic imagination: Genetic counseling amidst therapeutic innovation and evolving futures
Authors: Mueller Rebecca 
Published: December 2022

AbstractDespite the moniker “precision medicine,” genetic diagnoses are often imprecise with respect to prognosis. In a period when prognoses are evolving in lockstep with advances in genetic diagnostics and therapeutics, it is critical that clinicians and researchers consider how prognosis is communicated beyond the moment of diagnosis. Research has shown that genetic diagnoses are described differently in pre‐ and postnatal contexts, but we know relatively little about how patients and families make sense of prognostic information as affected children grow up. Here, I draw on research and personal narratives to describe how prognostic information impacts individuals' conceptions of the future. A deeper understanding of how patients and families view prognosis is important because parents may need support as prognostic conversations arise and because perceptions of prognosis may influence ideas about the future, psychological health, decisions, and planning. By exploring how specific ideas about an individuals' future take hold, clinicians and researchers may begin to identify the benefits, harms, and accuracy of varied sources of prognostic information, opening new areas of bioethical investigation. In closing, I propose prognostic imagination as a useful concept for considering how patients and families experience prognostic information amidst therapeutic innovations and evolving futures.
The experiences of families receiving a diagnosis of 22q11.2 deletion syndrome in Ireland
Authors: O'Donoghue Emma , McAllister Marion , Rizzo Roberta 
Published: December 2022

AbstractFamilies in Ireland often wait over 1 year to see a genetic counselor (GC). This qualitative study aimed to explore the views of families who received a diagnosis of 22q11DS in Ireland regarding the need for timely access to genetic counseling at the point of diagnosis. Twenty participants were recruited through the ‘22q Ireland’ support group, giving a response rate of approximately 10% of the total support group members. Semi‐structured interviews were conducted online and by telephone which explored experiences of receiving diagnoses, medical care, genetic counseling, mental health, and coping with the diagnosis. Interviews were transcribed verbatim and analyzed using thematic analysis. The experiences of 20 participants were classified into five main themes: Receiving Diagnosis, Interactions with Healthcare Professionals (HCPs, excluding GCs), Medical Care, Information, and Impact of Condition. Participants reported receiving diagnoses for their children in a sub‐optimal manner due to inappropriate settings and insufficient information, support, and pre‐test counseling. Parents reported feeling responsible for managing their child's complex and fragmented medical care. Participants reported insufficient empathy and little awareness of 22q11DS among HCPs. Participants perceived genetic counseling to be associated with family planning and reported delayed, if any, access to services. Mental health was a particular worry among participants. Conferences about 22q11DS are the main source of information for parents. Participants reported a range of emotions after diagnosis and described the family impact. The findings suggest both an association between HCPs' poor understanding of 22q11DS and the perceived lack of empathy from HCPs and fragmented medical care. There is an identified need for advocacy of the GC profession in Ireland to support these families. Increased awareness of 22q11DS among HCPs and the development of a coordinated care pathway for 22q11DS, with timely access to genetic counseling, may improve care and lead to better outcomes.
Electromagnetic interferences susceptibility analysis for a metasurface‐modified wireless power transfer system
Authors: Liang Tao , Barmada Sami , Fontana Nunzia , Xie Yan‐zhao , Brizi Danilo , Monorchio Agostino 
Published: December 2022

AbstractThe use of magnetic metasurfaces in Wireless Power Transfer systems is becoming a popular research topic: they have proven to be a valid approach to increase the performances (in terms of power transfer) and improve the overall EMC properties in terms of field emissions. In this contribution, the authors investigate the susceptibility of such systems in case of an impinging Electromagnetic Interference (that might also be intentional), evaluating different parameters for a selected set of the system's components. In particular, the worst‐case scenarios of voltage peak, energy and sharpness (where appliable) at the transmitting and receiving ports and at each capacitor of the metasurface are calculated. The results obtained for a specific system practically implemented in the lab, show that the metasurface does not necessarily decreases susceptibility towards EMI and it can be itself the most critical component. The identification of the key and critical parameters allows us to provide an insight on how metamaterials used as shielding devices should be properly designed.
Plantation understorey legume functional groups enhance soil organic carbon sequestration by promoting species richness
Authors: Wang Cong , Wang Shuai , Fu Bojie , Li Zongshan , Lü Yihe 
Published: December 2022

AbstractDespite evidence showing that plant diversity or tree mixtures increase carbon storage in experimental grasslands or mixed forests, the effects of understorey plant communities on changes in soil organic carbon (SOC) storage in planted forests remain unclear, especially for monoculture plantations. Therefore, based on field observations in monoculture plantations on the Loess Plateau in China, we investigated the direct effects of understorey species richness (USR) and plantation age on SOC storage, and identified the indirect effects of understorey legume species richness (ULSR) and soil moisture (SM) mediated by USR. Results indicated that plantation age and USR significantly increased SOC sequestration with almost equal effects. The changes in the relationship between USR and SOC storage varied along the water availability gradient, from significantly positive (in plots with SM ≤11.14%) to insignificant (in plots with SM >11.14%). We observed that ULSR could increase SOC sequestration by promoting USR, while SM had negative and positive effects on ULSR and USR, respectively. Our findings can provide insights into plantation management in semiarid regions: Thinning mature plantations and introducing understorey legumes can increase SOC sequestration and maintain water resource sustainability.