bluuebunny/crossref_metadata_2025_split huggingface dataset:
Parathyroid fine‐needle aspiration with parathyroid hormone washout as a preoperative localisation of parathyroid adenoma—A retrospective study
Authors: Klein Pinchas , Alsleibi Shibli , Cohen Ohad , Ilany Jacob , Hemi Rina , Barhod Ehud , Vered Iris , Winder Ophir , Avior Galit , Tripto‐Shklonik Liana 
Published: June 2023

AbstractObjectiveThe use of parathyroid lesion aspiration in preoperative adenoma localisation is controversial. Concerns have been raised regarding both immediate safety (hematoma, infection, alterations on a subsequent histologic preparate) and long‐term safety (seeding). We aimed to evaluate the short‐ and long‐term safety, and the efficacy, of parathyroid fine‐needle aspiration with parathyroid hormone washout as a localisation modality of parathyroid adenoma in patients with primary hyperparathyroidism.DesignA retrospective study.PatientsThe sample comprised 29 patients with primary hyperparathyroidism who underwent minimally invasive parathyroidectomy at a tertiary referral centre, following localisation with parathyroid hormone washout.MeasurementsWe reviewed all parathyroid hormone washout procedures performed during 2011–2021. Clinical, biochemical, and imaging information; and cytology, surgery, and pathology reports were extracted from electronic medical records.ResultsParathyroid hormone levels from the needle wash were 2.1–112.5 times the upper limit of the serum norm. Other than mild neck discomfort, no immediate procedure complications were documented. Fibrotic changes and necrosis were reported in two patients, with no effect on the final pathologic diagnosis or surgery course. No long‐term complications (seeding, or parathyromatosis) were found. A total of 26 (90%) patients who were operated following a positive parathyroid hormone washout result were normocalcemic at the end of a mean 38.1‐month follow‐up period.ConclusionsParathyroid fine‐needle aspiration with parathyroid hormone washout was accurate. Immediate, surgical, or delayed complications were not demonstrated in our series. This approach might be considered for selected patients.
The use of corporal punishment and physical disciplinary techniques by Flemish mothers
Authors: Vanderfaeillie Johan , Van Eynde Kaat , Van Blyenbergh Elien , Verheyden Camille , Van Dooren Erik , Van Holen Frank 
Published: June 2023

AbstractCorporal punishment (CP) of children has many negative consequences, yet many parents still use CP to discipline their child. This study used an online questionnaire to determine the prevalence of CP among Flemish mothers, which specific physical disciplinary techniques (PDT) they consider CP and which PDT they use. In addition, the association of attitudes regarding CP, personal experiences with CP and cultural acceptance with the use of CP was examined. A total of 411 Flemish mothers with a child aged between 2 and 11 years participated in the study. About 38% of the mothers reported to use CP. In case of the use of PDT, they mostly used mild PDT. The results also show that there is a lack of consensus regarding the conceptualization of CP among Flemish mothers. Furthermore, positive attitudes towards the use of CP was a predictor of its use. Because the use of CP is associated with many negative consequences, it is important to set up prevention programmes to dissuade mothers form using of CP, to alter positive attitudes regarding CP and to raise awareness regarding the negative impact of CP on the development of children.
Biogeographic–tectonic calibration of 14 nodes in a butterfly timetree
Authors: Heads Michael , Grehan John R. , Nielsen John , Patrick Brian 
Published: June 2023

AbstractThe butterfly subtribe Coenonymphina (Nymphalidae: Satyrinae) comprises four main clades found, respectively, in (1) the Solomon Islands, (2) Australasia, (3) NW South America and (4) Laurasia, with a phylogeny: 1 (2 (3 + 4)). In assessing biogeographic evolution in the group we rejected the conversion of fossil‐calibrated clade ages to likely maximum clade ages by the imposition of arbitrary priors. Instead, we used biogeographic–tectonic calibration, with fossil‐calibrated ages accepted as minima. Previous studies have used this approach to date single nodes (phylogenetic–biogeographic breaks) in a group, but we extended the methodology to date multiple nodes. Within the Coenonymphina as a whole, 14 nodes coincide spatially with ten major tectonic events. In addition, the phylogenetic sequence of these nodes conforms to the chronological sequence of the tectonic events, consistent with a vicariance origin of the clades. Dating of the spatially coincident tectonic features provides a timescale for the vicariance events. The tectonic events are: pre‐drift intracontinental rifting between India and Australia (150 Ma); seafloor spreading at the margins of the growing Pacific plate, and between North and South America (140 Ma); magmatism flare‐up along the SW Pacific Whitsunday Volcanic Province–Median Batholith (130 Ma); a change from extension in the Clarence basin, eastern Australia, to uplift of the Great Dividing Range (114 Ma); Pamir Mountains uplift, foreland basin dynamics and high eustatic sea‐levels leading to marine transgression of the proto‐Paratethys Ocean eastward to Central Asia and Xinjiang (100 Ma); predrift rifting and seafloor spreading west of New Caledonia (100–50 Ma); sinistral strike‐slip displacement along the proto‐Alpine fault, New Zealand (100–80 Ma); thrust faulting in the Longmen Shan and foreland basin dynamics around the Sichuan Basin (85 Ma); pre‐drift rifting in the Coral Sea basin (85 Ma); and dextral displacement on the Alpine fault (20 Ma).
Multiple sevoflurane exposures during mid‐trimester induce neurotoxicity in the developing brain initiated by 15LO2‐Mediated ferroptosis
Authors: Jiang Qian , Wang Cong , Gao Qiushi , Wu Ziyi , Zhao Ping 
Published: June 2023

AbstractAimsMid‐gestational sevoflurane exposure may induce notable long‐term neurocognitive impairment in offspring. This study was designed to investigate the role and potential mechanism of ferroptosis in developmental neurotoxicity induced by sevoflurane in the second trimester.MethodsPregnant rats on day 13 of gestation (G13) were treated with or without 3.0% sevoflurane, Ferrostatin‐1 (Fer‐1), PD146176, or Ku55933 on three consecutive days. Mitochondrial morphology, ferroptosis‐relative proteins, malondialdehyde (MDA) levels, total iron content, and glutathione peroxidase 4 (GPX4) activities were measured. Hippocampal neuronal development in offspring was also examined. Subsequently, 15‐lipoxygenase 2 (15LO2)‐phosphatidylethanolamine binding protein 1 (PEBP1) interaction and expression of Ataxia telangiectasia mutated (ATM) and its downstream proteins were also detected. Furthermore, Morris water maze (MWM) and Nissl's staining were applied to estimate the long‐term neurotoxic effects of sevoflurane.ResultsFerroptosis mitochondria were observed after maternal sevoflurane exposures. Sevoflurane elevated MDA and iron levels while inhibiting GPX4 activity, and resultant long‐term learning and memory dysfunction, which were alleviated by Fer‐1, PD146176, and Ku55933. Sevoflurane could enhance 15LO2‐PEBP1 interaction and activate ATM and its downstream P53/SAT1 pathway, which might be attributed to excessive p‐ATM nuclear translocation.ConclusionThis study proposes that 15LO2‐mediated ferroptosis might contribute to neurotoxicity induced by maternal sevoflurane anesthesia during the mid‐trimester in the offspring and its mechanism may be ascribed to hyperactivation of ATM and enhancement of 15LO2‐PEBP1 interaction, indicating a potential therapeutic target for ameliorating sevoflurane‐induced neurotoxicity.
“People Around Here Like Their Fruits and Vegetables”: Eating, Growing Food, and Food Sovereignty in Eastern Kentucky
Authors: Koempel Annie 
Published: June 2023

AbstractThis article explores community‐based food production and sharing practices in eastern Kentucky that are often obscured by dominant neoliberal paradigms and market‐based solutions. I begin with an orientation to eastern Kentucky, which is nestled in the mountains of central Appalachia, and its history of economic precarity and subsistence. Next I introduce my methods, followed by discussions of food sovereignty. Through the presentation of ethnographic evidence from participant observation and in‐depth, semi‐structured interviews in eastern Kentucky, I illustrate an extant “quiet food sovereignty”—community‐based food production that is overlooked by institutions and unrecognized by practitioners as constituting food sovereignty. I argue that any push to marketize growing, gathering, and/or hunting food in eastern Kentucky is not the solution to economic precarity or poor public health in that part of the state. As I illustrate, small farming (or large farming, for that matter) is not an economically viable (although socially and culturally valuable) option in the United States. Instead, I argue for local and federal efforts that support community food sovereignty.
Predictors of self‐reported sexually transmitted infections among Turkish university students
Authors: Gülsoy Seçil Seymenler , Siyez Ender , Esen Erol , Baran Bahar , Siyez Diğdem Müge 
Published: June 2023

SummaryBackground and aimSexually transmitted infections (STIs) are among the most crucial health problems that sexually active university students may encounter. This study aims to identify the predictors of self‐reported STIs among university students.MethodsStudy participants were 2,241 individuals who reported having had sexual intercourse among a cohort of 9,693 students surveyed from 21 Turkish universities. The age of participants ranged from 17 years to 28 years.ResultsThe Chi‐Square Automatic Interaction Detection (CHAID) analysis indicated that gender was the main predictor of self‐reported STI. Also, number of partners and substance use were found as predictor variables for males. Finally, the classification accuracy of the CHAID model was found to be 95.3% within the sample.ConclusionsThe present findings shed light on risk factors for STI acquisition, suggesting possible directions for tailoring future preventive interventions.
Cross‐sectional and longitudinal assessment of cognitive development in Williams syndrome
Authors: Farran Emily K. , Purser Harry R. M. , Jarrold Christopher , Thomas Michael S. C. , Scerif Gaia , Stojanovik Vesna , Van Herwegen Jo 
Published: June 2023

AbstractWilliams syndrome (WS) is a rare genetic syndrome. As with all rare syndromes, obtaining adequately powered sample sizes is a challenge. Here we present legacy data from seven UK labs, enabling the characterisation of cross‐sectional and longitudinal developmental trajectories of verbal and non‐verbal development in the largest sample of individuals with WS to‐date. In Study 1, we report cross‐sectional data between N = 102 and N = 209 children and adults with WS on measures of verbal and non‐verbal ability. In Study 2, we report longitudinal data from N = 17 to N = 54 children and adults with WS who had been tested on at least three timepoints on these measures. Data support the WS characteristic cognitive profile of stronger verbal than non‐verbal ability, and shallow developmental progression for both domains. Both cross‐sectional and longitudinal data demonstrate steeper rates of development in the child participants than the adolescent and adults in our sample. Cross‐sectional data indicate steeper development in verbal than non‐verbal ability, and that individual differences in the discrepancy between verbal and non‐verbal ability are largely accounted for by level of intellectual functioning. A diverging developmental discrepancy between verbal and non‐verbal ability, whilst marginal, is not mirrored statistically in the longitudinal data. Cross‐sectional and longitudinal data are discussed with reference to validating cross‐sectional developmental patterns using longitudinal data and the importance of individual differences in understanding developmental progression.
The Actuality of the Council of Nicaea
Authors: (Getcha) Metropolitan Job 
Published: June 2023

AbstractThe year 2025 will mark the 1700th anniversary of the First Ecumenical Council, the Council of Nicaea, which initiated a new chapter in the history of the Christian Church. The World Council of Churches is planning to organize a World Conference on Faith and Order to celebrate this anniversary and to reflect on the transmission of the apostolic faith today. This conference is not intended to study the history of the council nor to study its theology, but rather to reflect on what “visible unity” means to different Christian churches and how Christians can collectively promote, preach, and live the apostolic faith today in the context of many contemporary challenges, such as secularization and religious pluralism. In this perspective, the present article reflects on the actuality of the Council of Nicaea and how it still ought to be considered as normative for the Christians of the 21st century.
What Future for the Ecumenical Movement?
Authors: Sauca Ioan 
Published: June 2023

AbstractThis is an edited version of a lecture given by Ioan Sauca in February 2023 at the Study Centre for the Eastern Churches at the Institute for Ecumenical Studies of the University of Fribourg, Switzerland, at the invitation of Professor Barbara Hallensleben. The lecture takes stock of Sauca's experience as a World Council of Churches (WCC) staff member, professor, and director of the Ecumenical Institute at Bossey and, more recently, as the first Orthodox to serve as acting general secretary of the WCC; from that experience and learning, Ioan Sauca draws conclusions about the future of the ecumenical movement.
Preservation of epidermal melanocyte integrity in an ex vivo co‐culture skin model with sebocytes
Authors: Abdel‐Naser Mohamed Badawy , Nikolakis Georgios , Zouboulis Christos C. 
Published: June 2023

AbstractA direct contact co‐culture of skin explants to SZ95 sebocytes (3D‐SeboSkin) has been shown to preserve the integrity of epidermal keratinocytes and dermis. In this study, the properties of epidermal melanocytes were evaluated in the same 3D SeboSkin ex vivo model. Skin explants (n = 6) were maintained in the 3D‐SeboSkin model, in direct contact to fibroblasts and alone in serum‐free medium (SFM). Histopathological, immunohistochemical, apoptosis and oil red staining evaluations were performed at Days 0 and 6 of incubation. Results revealed preservation and prominent proliferation of basal keratinocytes of the skin explants in addition to preservation of dermal collagen and vasculature at Day 6 in the 3D‐SeboSkin culture model and to a lesser extent in co‐culture with fibroblasts but not in SFM alone. Melan‐A+/Ki67‐ epidermal melanocytes remained attached to the dermis even at sites of epidermal detachment in the three skin explant models tested. However, the number of epidermal melanocytes was significantly conserved in 3D‐SeboSkin cultures in comparison with skin explants in SFM (p < 0.05), whereas no difference was found in comparison with the co‐culture with fibroblasts. Few DAPI/TUNEL+ apoptotic melanocytes could mostly be observed in SFM‐incubated skin explants. Furthermore, only SZ95 sebocytes in contact to skin explants in 3D‐SeboSkin exhibited increased lipogenesis with accumulation of abundant lipid droplets. These results denote that the 3D‐SeboSkin model yielded significant preservation of epidermal melanocytes and hence it is optimal for ex vivo studies of abnormalities of skin pigmentation, melanocyte neoplasms and effects of different hormones, cytokines, carcinogens and various therapeutics in a pattern that recapitulates the in vivo environment.
Opposition‐based ideal gas molecular movement algorithm with Cauchy mutation, velocity clamping, and mirror operator
Authors: Safari Mahsa , Varaee Hesam 
Published: June 2023

AbstractThe ideal gas molecular movement (IGMM) as a metaheuristic optimization method is a prominent option for solving optimization problems. However, in some complex cases, IGMM may possess premature convergence or get trapped in local optima. Therefore, to tackle these issues, this paper indicates a new modified IGMM algorithm named opposition‐based IGMM, which has been incorporated with opposition based learning (OBL), Cauchy mutation (CM), velocity clamping (VC), and mirror operator (MO) to enhance its performance. OBL, VC, and MO improve the convergence of IGMM, whereas CM assists IGMM to escape local optima. The effect of each strategy, OBL, CM, VC, and MO, on IGMM, is confirmed through 30 low and high‐dimensional benchmarks, including 23 well‐known mathematical problems and CEC2017 as complex test functions and three engineering problems. Analysis results represent that integration IGMM with OBL, CM, VC, and MO has the best performance among other IGMM variants and eventually improved IGMM in exploration, exploitation, accelerating convergence, and local optima avoidance.
Keeping up with the Joneses? Evidence from Peer Performance in the Banking Industry
Authors: Dbouk Wassim , Kryzanowski Lawrence 
Published: June 2023

AbstractThis paper traces the reaction of US banks to ROE underperformance on liquidity creation, equity capital, and loan loss provisions. We find that banks change their structures in the subsequent quarter after underperformance by increasing their on‐balance and off‐balance sheet liquidity creation to increase profitability. Banks tend to increase their equity capital and improve their loan quality by lowering non‐discretionary loan loss provisions to become safer. Banks signal their ability to overcome underperformance by increasing their discretionary loan loss provisions. Our results reveal that large banks rely mainly on off‐balance sheet liquidity creation as their primary tool to recover from underperformance while medium‐size and small banks adjust their equity capital to increase their safety.
Elemental stoichiometry of the key calcifying marine phytoplankton Emiliania huxleyi under ocean climate change: A meta‐analysis
Authors: Sheward Rosie M. , Liefer Justin D. , Irwin Andrew J. , Finkel Zoe V. 
Published: June 2023

AbstractThe elemental composition of marine microorganisms (their C:N:P ratio, or stoichiometry) is central to understanding the biotic and biogeochemical processes underlying key marine ecosystem functions. Phytoplankton C:N:P is species specific and flexible to changing environmental conditions. However, bulk or fixed phytoplankton stoichiometry is usually assumed in biogeochemical and ecological models because more realistic, environmentally responsive C:N:P ratios have yet to be defined for key functional groups. Here, a comprehensive meta‐analysis of experimental laboratory data reveals the variable C:N:P stoichiometry of Emiliania huxleyi, a globally significant calcifying phytoplankton species. Mean C:N:P of E. huxleyi is 124C:16N:1P under control conditions (i.e. growth not limited by one or more environmental stressors) and shows a range of responses to changes in nutrient and light availability, temperature and pCO2. Macronutrient limitation caused strong shifts in stoichiometry, increasing N:P and C:P under P deficiency (by 305% and 493% respectively) and doubling C:N under N deficiency. Responses to light, temperature and pCO2 were mixed but typically shifted cellular elemental content and C:N:P stoichiometry by ca. 30% or less. Besides these independent effects, the interactive effects of multiple environmental changes on E. huxleyi stoichiometry under future ocean conditions could be additive, synergistic or antagonistic. To synthesise our meta‐analysis results, we explored how the cellular elemental content and C:N:P stoichiometry of E. huxleyi may respond to two hypothetical future ocean scenarios (increased temperature, irradiance and pCO2 combined with either N deficiency or P deficiency) if an additive effect is assumed. Both future scenarios indicate decreased calcification (which is predominantly sensitive to elevated pCO2), increased C:N, and up to fourfold shifts in C:P and N:P. Our results strongly suggest that climate change will significantly alter the role of E. huxleyi (and potentially other calcifying phytoplankton species) in marine biogeochemical processes.
International Council for Standardization in Haematology recommendations for laboratory measurement of factorVIIIandFIXtypeIinhibitors
Authors: Meijer Piet , Peyvandi Flora , Young Guy , Pruthi Rajiv , de Lima Montalvão Silmara , Kitchen Steve 
Published: June 2023

AbstractThis guidance document has been prepared on behalf of the International Council for Standardisation in Hematology. The aim of the document is to provide guidance and recommendations on the measurement of factor VIII (FVIII) and factor IX (FIX) inhibitors. After an introduction on the clinical background and relevance of factor VIII and factor IX inhibitor testing, the following aspects of laboratory testing are included: screening for inhibitors, assay principle, sample requirements, testing requirements and interpretation, quality assurance, interferences and recent developments. This guidance document focusses on recommendations for a standardised procedure for the laboratory measurement of FVIII and FIX type I inhibitors. The recommendations are based on published data in peer‐reviewed literature and expert opinion.
Infant effortful control predicts BMI trajectories from infancy to adolescence
Authors: Deer LillyBelle K. , Doom Jenalee R. , Harrall Kylie K. , Glueck Deborah H. , Glynn Laura M. , Sandman Curt A. , Davis Elysia Poggi 
Published: June 2023

SummaryBackgroundEffortful control, or the regulation of thoughts and behaviour, is a potential target for preventing childhood obesity.ObjectivesTo assess effortful control in infancy through late childhood as a predictor of repeated measures of body mass index (BMI) from infancy through adolescence, and to examine whether sex moderates the associations.MethodsMaternal report of offspring effortful control and measurements of child BMI were obtained at 7 and 8 time points respectively from 191 gestational parent/child dyads from infancy through adolescence. General linear mixed models were used.ResultsEffortful control at 6 months predicted BMI trajectories from infancy through adolescence, F(5,338) = 2.75, p = 0.03. Further, when effortful control at other timepoints were included in the model, they added no additional explanatory value. Sex moderated the association between 6‐month effortful control and BMI, F(4, 338) = 2.59, p = 0.03, with poorer infant effortful control predicting higher BMI in early childhood for girls, and more rapid increases in BMI in early adolescence for boys.ConclusionsEffortful control in infancy was associated with BMI over time. Specifically, poor effortful control during infancy was associated with higher BMI in childhood and adolescence. These findings support the argument that infancy may be a sensitive window for the development of later obesity.