bluuebunny/crossref_metadata_2025_split huggingface dataset:
The utility of adoptionism as a heuristic category: The baptism narrative in the Gospel of the Ebionites as a test case
Authors: Kok Michael 
Published: January 2023

AbstractAlthough the Christology of the Ebionites in general, and the so-called Gospel of the Ebionites cited by Epiphanius of Salamis in particular, has been commonly classified as adoptionist, the utility of the term ‘adoptionism’ has been recently called into question. This article will focus on the fragment about Jesus’ baptism in Panarion, 30.13.7–8 to determine whether it depicts Jesus’ adoption to divine sonship. Although the text does not use adoptionist terminology and imagery, Jesus does acquire a new christological identity in the pericope when he is possessed by the spirit and metaphorically begotten by the deity. This should be relabelled as a possessionist Christology. However, Epiphanius wrongly interpreted the text through the lens of Cerinthus’ Christology, in which Jesus is only temporarily inhabited by the Christ aeon between his baptism and his crucifixion.
Scaling up health technology assessment capacities in selected African countries – A conceivable route ahead
Authors: Mueller Debjani , Alouane Leila , Jameleddine Mouna , Lenoir-Wijnkoop Irene 
Published: January 2023

Abstract

Background
This study aimed to provide a structured description of the commonalities and differences in healthcare structures across Africa to establish a reliable basis for the health technology assessment (HTA) of nutrition and nutrition interventions. A ranking of current nutrition conditions in the general population of the participating countries was included to gain a better understanding of the factors influencing hospital malnutrition (HMN), which will inform future multi-country research.

Method
A questionnaire on the structure of the health systems was distributed among ten African countries. Subsections were included that inquired about the drivers or barriers to using principles of HTA to assess nutritional care. Analysis and ranking of malnutrition data were based on data from the Global Hunger Index report and two poverty indicators used by the World Bank.

Results
The health system structure of each country was identified and described, whereas questions about HTA could not always be analyzed due to a lack of adequate in-depth knowledge and skills in most countries. Early experience from some countries demonstrates a conceivable route ahead for African countries in strengthening the capacity for and implementing HTA in accordance with distinct national healthcare contexts and social determinants of health.

Conclusion
Problems related to nutritional care represent one of the major priorities in the surveyed countries. A future HMN multi-country study will provide valuable insight into the potential of low-cost primary prevention orientations.
In Interview: Key Features of Contemporary British Drama
Authors: Sierz Aleks , Günenç Mesut 
Published: January 2023

In this interview on 22 March 2022 in London, Mesut Gunenc talks to theatre critic and historian Aleks Sierz about how his work has influenced contemporary British drama, why he chose the name ‘in-yer-face theatre’ for 1990s avant-garde plays, and why some writers have rejected the label. They also discuss the differences between experiential and experimental theatre, especially focusing on the work of Anthony Neilson, and finish by considering the key themes that characterize 1990s new writing in Britain.Aleks Sierz is author of the seminal In-Yer-Face Theatre: British Drama Today (Faber, 2001), as well as of other work about new writing and post-war British theatre history. His more recent books include Rewriting the Nation: British Theatre Today (Methuen Drama, 2011), Modern British Playwriting: The 1990s (Methuen Drama, 2012), and Good Nights Out: A History of Popular British Theatre Since the Second World War (Methuen Drama, 2021). He has co-authored, with Lia Ghilardi, The Time Traveller’s Guide to British Theatre: The First Four Hundred Years (Oberon, 2015). Mesut Gunenc is Assistant Professor in the Department of English Language and Literature at Adnan Menderes University in Turkey. He is the author of Postdramatic Theatrical Signs in Contemporary British Playwrights (Lambert, 2017) and co-editor, with Enes Kavak, of New Readings in British Drama: From the Post-War Period to the Contemporary Era (Peter Lang, 2021). He is currently a visiting postdoctoral scholar at Loughborough University in the UK.
The Magic of WDEP in Reality Therapy
Authors: Arab Arefe , Khodabakhshi-Koolaee Anahita 
Published: January 2023

Abstract. Background: Reality therapy’s WDEP helps people to become aware of their wants and to engage in directing, evaluating, and planning to recognize the challenges and find solutions to them. This study examined the effect of reality therapy intervention on marital intimacy needs and communication patterns in married men. Methods: We conducted this quasiexperimental study using a pretest-posttest design with a control group. The participants were 30 men selected using simple random sampling who were placed into two intervention and control groups, each of 15 persons. The data were collected using the Communication Patterns Questionnaire ( Christensen & Sullaway, 1984 ) and the Marital Intimacy Needs Questionnaire (MINQ; Bagarozzi, 1997 ). We performed the reality therapy intervention for the members of the intervention groups in 8 sessions of 90 minutes. We then analyzed the collected data using analysis of covariance (ANCOVA) with SPSS software (version 26). Analysis: The implementation of the reality therapy intervention increased the couples’ scores of intimacy needs and all its subscales ( p < .05). Further, there was an increase in constructive relationships with the spouse in the intervention group ( p < .01). However, these changes were not observed in the participants in the control group. Conclusion: Since the reality therapy intervention focuses on accepting responsibility, valuing thinking, and acting in life instead of making excuses, it can help married men to identify their intimacy needs and establish more effective communication with their wives.
Future Local Ground‐Level Ozone in the European Area From Statistical Downscaling Projections Considering Climate and Emission Changes
Authors: Hertig Elke , Jahn Sally , Kaspar‐Ott Irena 
Published: January 2023

AbstractGround‐level ozone is a major air pollutant harmful to human health. In the scope of climate change, it is essential to provide high‐quality local‐scale assessments of the anticipated changes for public health and policy interventions. Assessments and projections of ground‐level ozone usually rely on numerical modeling, but statistical approaches are also available. The present study enhances the validity of statistical downscaling by taking climate change as well as air pollution changes into account. Besides considering meteorological predictors such as air temperature, short‐wave radiation, humidity, and wind, ozone trends from changes in precursor emissions were included in the statistical models. Meteorological and ozone predictor information extracted from reanalysis data for the observational period and output of seven Earth System Models (ESMs) for the projection periods were used, with three of them having interactive chemical modeling, while the other four used prescribed ozone changes. Ground‐level ozone, more precisely daily maximum 8‐hr running means (MDA8) as well as daily maximum 1‐hr values (MDA1), at 798 measurement stations across the European area in the “ozone season” from April to September were assessed. Results depended strongly on whether only meteorological information or additional information about emission changes were considered. As a general picture under the consideration of climate and emission changes, decreasing ground‐level ozone concentrations were projected under the moderate SSP2‐4.5 scenario, while for the more pessimistic scenario SSP3‐7.0 increasing ozone concentrations over Europe, especially at the end of the 21st century, were assessed.
Meplazumab in hospitalized adults with severe COVID-19 (DEFLECT): a multicenter, seamless phase 2/3, randomized, third-party double-blind clinical trial
Authors: Bian Huijie , Chen Liang , Zheng Zhao-Hui , Sun Xiu-Xuan , Geng Jie-Jie , Chen Ruo , Wang Ke , Yang Xu , Chen Shi-Rui , Chen Si-Yu , Xie Rong-Hua , Zhang Kui , Miao Jin-Lin , Jia Jun-Feng , Tang Hao , Liu Shuang-Shuang , Shi Hong-Wei , Yang Yong , Chen Xiao-Chun , Malhotra Vinay , Nasir Nosheen , Khanum Iffat , Mahmood Faisal , Hamid Saeed , Stadnik Claudio Marcel Berdun , Itinose Kengi , de Oliveira Caroline Cândida Carvalho , Dusilek Cesar , Rivabem Lucas , Cavalcante Adilson Joaquim Westheimer , Lopes Suzara Souto , Saporito Wladmir Faustino , Fucci Fábio José Concilio , Simon-Campos Jesus Abraham , Wang Ling , Liu Lin-Na , Wang Qing-Yi , Wei Ding , Zhang Zheng , Chen Zhi-Nan , Zhu Ping 
Published: January 2023

AbstractMeplazumab, a humanized CD147 antibody, has shown favourable safety and efficacy in our previous clinical studies. In DEFLECT (NCT04586153), 167 patients with severe COVID-19 were enroled and randomized to receive three dosages of meplazumab and a placebo. Meplazumab at 0.12 mg/kg, compared to the placebo group, showed clinical benefits in significantly reducing mortality by 83.6% (2.4% vs. 14.6%, p = 0.0150), increasing the proportion of patients alive and discharged without supplemental oxygen (82.9% vs. 70.7%, p = 0.0337) and increasing the proportion of patients who achieved sustained clinical improvement (41.5% vs. 31.7%). The response rate in the 0.2 mg/kg group was relatively increased by 16.0% compared with the placebo group (53.7% vs. 46.3%). Meplazumab also reduced the viral loads and multiple cytokine levels. Compare with the placebo group, the 0.3 mg/kg significantly increased the virus negative rate by 40.6% (p = 0.0363) and reduced IL-8 level (p = 0.0460); the 0.2 mg/kg increased the negative conversion rate by 36.9%, and reduced IL-4 (p = 0.0365) and IL-8 levels (p = 0.0484). In this study, the adverse events occurred at a comparable rate across the four groups, with no unexpected safety findings observed. In conclusion, meplazumab promoted COVID-19 convalescence and reduced mortality, viral load, and cytokine levels in severe COVID-19 population with good safety profile.
Genetic diversity and local adaption of alfalfa populations (Medicago sativa L.) under long-term grazing
Authors: Wang Hu , Coulman Bruce , Bai Yuguang , Tarˈan Bunyamin , Biligetu Bill 
Published: January 2023

AbstractGenomic information on alfalfa adaptation to long-term grazing is useful for alfalfa genetic improvement. In this study, 14 alfalfa populations were collected from long-term grazing sites (> 25 years) across four soil zones in western Canada. Alfalfa cultivars released between 1926 and 1980 were used to compare degree of genetic variation of the 14 populations. Six agro-morphological and three nutritive value traits were evaluated from 2018 to 2020. The genotyping-by-sequencing (GBS) data of the alfalfa populations and environmental data were used for genotype-environment association (GEA). Both STRUCTURE and UPGMA based on 19,853 SNPs showed that the 14 alfalfa populations from long-term grazing sites had varying levels of parentages from alfalfa sub-species Medicago sativa and M. falcata. The linear regression of STRUCTURE membership probability on phenotypic data indicated genetic variations of forage dry matter yield, spring vigor and plant height were low, but genetic variations of regrowth, fall plant height, days to flower and crude protein were still high for the 14 alfalfa populations from long-term grazing sites. The GEA identified 31 SNPs associated with 13 candidate genes that were mainly associated with six environmental factors of. Candidate genes underlying environmental factors were associated with a variety of proteins, which were involved in plant responses to abiotic stresses, i.e., drought, cold and salinity-alkali stresses.
The collaborative role of blockchain, artificial intelligence, and industrial internet of things in digitalization of small and medium-size enterprises
Authors: Khan Abdullah Ayub , Laghari Asif Ali , Li Peng , Dootio Mazhar Ali , Karim Shahid 
Published: January 2023

AbstractDue to digitalization, small and medium-sized enterprises (SMEs) have significantly enhanced their efficiency and productivity in the past few years. The process to automate SME transaction execution is getting highly multifaceted as the number of stakeholders of SMEs is connecting, accessing, exchanging, adding, and changing the transactional executions. The balanced lifecycle of SMEs requires partnership exchanges, financial management, manufacturing, and productivity stabilities, along with privacy and security. Interoperability platform issue is another critical challenging aspect while designing and managing a secure distributed Peer-to-Peer industrial development environment for SMEs. However, till now, it is hard to maintain operations of SMEs' integrity, transparency, reliability, provenance, availability, and trustworthiness between two different enterprises due to the current nature of centralized server-based infrastructure. This paper bridges these problems and proposes a novel and secure framework with a standardized process hierarchy/lifecycle for distributed SMEs using collaborative techniques of blockchain, the internet of things (IoT), and artificial intelligence (AI) with machine learning (ML). A blockchain with IoT-enabled permissionless network structure is designed called “B-SMEs” that provides solutions to cross-chain platforms. In this, B-SMEs address the lightweight stakeholder authentication problems as well. For that purpose, three different chain codes are deployed. It handles participating SMEs' registration, day-to-day information management and exchange between nodes, and analysis of partnership exchange-related transaction details before being preserved on the blockchain immutable storage. Whereas AI-enabled ML-based artificial neural networks are utilized, the aim is to handle and optimize day-to-day numbers of SME transactions; so that the proposed B-SMEs consume fewer resources in terms of computational power, network bandwidth, and preservation-related issues during the complete process of SMEs service deliverance. The simulation results present highlight the benefits of B-SMEs, increases the rate of ledger management and optimization while exchanging information between different chains, which is up to 17.3%, and reduces the consumption of the system’s computational resources down to 9.13%. Thus, only 14.11% and 7.9% of B-SME’s transactions use network bandwidth and storage capabilities compared to the current mechanism of SMEs, respectively.
Comparative analysis of the relationship between four hepatic steatosis indices and muscle mass
Authors: Lee Taesic , Chung Tae-Ha 
Published: January 2023

AbstractSeveral studies have attempted to validate the relationship between hepatic steatosis and sarcopenia. The crucial limitation is to establish the status of hepatic steatosis by costly or invasive methods. Therefore, several models predicting non-alcoholic fatty liver disease (NAFLD) have been developed but have exhibited heterogeneous results. In this study, we aimed to review and compare four representative models and analyze their relationship with the risk of low muscle mass. Korea National Health and Nutrition Examination Surveys from 2008 to 2011 were used to confirm our hypothesis. Dual-energy X-ray absorptiometry was used to measure the amount of skeletal muscle mass. We used four hepatic steatosis indices: hepatic steatosis index (HSI), Framingham steatosis index (FSI), liver fat score (LFS), and fatty liver index (FLI). Multivariate linear and logistic regressions were used to reveal the relationship between NAFLD and low skeletal muscle index (LSMI). Pairs of FSI-FLI and HSI-FLI exhibited the best and second-best correlations among all possible pairs. The four hepatic steatosis models were associated with increased risk for LSMI. After removing the body mass index effect, HSI and FLI remained robust predictors for LSMI. NAFLD was a significant and potent risk factor for low skeletal muscle.
Examining mediators of associations of food insecurity and being bullied with suicide among in-school adolescents in Eswatini: a cross-sectional study
Authors: Motsa Mfundi President Sebenele , Chiou Hung-Yi , Sanna Mattia , Simelane Maswati S. , Shabalala Fortunate S. , Chen Yi-Hua 
Published: January 2023

AbstractWe examined the potential mediating roles of anxiety and loneliness on the association of concurrent food insecurity (FI) and being bullied (BB) with suicidal behavior (SB) in Eswatini, a lower-middle-income country. We used data from the Global School-based Student Health Survey (GSHS; N = 3264), which employed a two-stage cluster sampling: first, 25 schools were selected based on the proportionate probability of enrollment; second, classes were randomly selected. A self-reported 84-item GSHS questionnaire was used to collect data for students aged 13–17 years. FI was measured by requesting students to recall how often they went hungry because of a lack of food at home in the 30 days before the study. Multiple logistic regressions and binary mediation function was applied to examine mediating factors of SB. The prevalence of SB, FI, and BB among adolescents was 27.5%, 7.7%, and 30.2%, respectively. Moreover, the relationship between FI and BB with SB was partly (approximately 24%) mediated by anxiety and loneliness. Our results highlight the mediating roles of anxiety and loneliness in suicidal adolescents who experience FI and BB. In conclusion, interventions for alleviating SB in high-risk adolescents experiencing FI and BB should also be aimed at ameliorating anxiety and loneliness.
Kinetics of thermal degradation of raw lacquer enhanced by formaldehyde urea prepolymer
Authors: Xiao Qiang , Cao Yanjun , Zheng Wenyu , Hou Tianle , Gao Shuhang , Lyu Jianhua , Xiao Hui , Chen Yuzhu , Chen Ming 
Published: January 2023

AbstractIn this study, formaldehyde-urea prepolymer (FUP) were synthesized, which were used to modify the raw lacquer (RL) and this composition named LF, while the basic properties of the RL were tested. Thermal gravimetric (TG) analysis and scanning electron microscopy (SEM) were used to analyze the degradative characteristics and the surface morphology of RL before and after modification. The result indicated that FUP can significantly improve the performance of RL. The drying time of the LF is significantly shortened, the gloss, the pencil hardness, and the impact performance are significantly enhanced at the same time. TG analysis and thermal decomposition kinetics analysis illustrated that the thermal stability and the activation energy of LF2 were stronger than that of RL. In addition, SEM analysis illustrated that the surface smoothness of RL were also improved.
An urban crowd flow model integrating geographic characteristics
Authors: Zhang Yu , Wu Sheng , Zhao Zhiyuan , Yang Xiping , Fang Zhixiang 
Published: January 2023

AbstractPredicting urban crowd flow spatial distributions plays a critical role in optimizing urban public safety and traffic congestion management. The spatial dependency between regions and the temporal dynamics of the local crowd flow are two important features in urban crowd flow prediction. However, few studies considered geographic characteristic in terms of spatial features. To fill this gap, we propose an urban crowd flow prediction model integrating geographic characteristics (FPM-geo). First, three geographic characteristics, proximity, functional similarity, and road network connectivity, are fused by a residual multigraph convolution network to model the spatial dependency relationship. Then, a long short-term memory network is applied as a framework to integrate both the temporal dynamic patterns of local crowd flow and the spatial dependency between regions. A 4-day mobile phone dataset validates the effectiveness of the proposed method by comparing it with several widely used approaches. The result shows that the root mean square error decreases by 15.37% compared with those of the typical models with the prediction interval at the 15-min level. The prediction error increases with the crowd flow size in a local area. Moreover, the error reaches the top of the morning peak and the evening peak and slopes down to the bottom at night.
Transmutation of MAs and LLFPs with a lead-cooled fast reactor
Authors: Sun X. Y. , Han L. H. , Li X. X. , Hu B. L. , Luo W. , Liu L. 
Published: January 2023

AbstractThe management of nuclear wastes has long been a problem that hinders the sustainable and clean utilization of nuclear energy since the advent of nuclear power. These nuclear wastes include minor actinides (MAs: 237Np, 241Am, 243Am, 244Cm and 245Cm) and long-lived fission products (LLFPs: 79Se, 93Zr, 99Tc, 107Pd, 129I and 135Cs), and yet are hard to be handled. In this work, we propose a scheme that can transmute almost all the MAs and LLFPs with a lead-cooled fast reactor (LFR). In this scheme, the MAs and the LLFPs are loaded to the fuel assembly and the blanket assembly for transmutation, respectively. In order to study the effect of MAs loading on the operation of the core, the neutron flux distribution, spectra, and the keff are further compared with and without MAs loading. Then the LLFPs composition is optimized and the support ratio is obtained to be 1.22 for 237Np, 1.63 for 241Am, 1.27 for 243Am, 1.32 for 79Se, 1.53 for 99Tc, 1.02 for 107Pd, and 1.12 for 129I, respectively, indicating that a self-sustained transmutation can be achieved. Accordingly, the transmutation rate of these nuclides was 13.07%/y for 237Np, 15.18%/y for 241Am, 13.34%/y for 243Am, 0.58%/y for 79Se, 0.92%/y for 99Tc, 1.17%/y for 107Pd, 0.56%/y for 129I. Our results show that a lead-cooled fast reactor can be potentially used to manage nuclear wastes with high levels of long-lived radioactivity.
Diffusion of cosmic-ray electrons in M 51 observed with LOFAR at 54 MHz
Authors: Heesen V. , de Gasperin F. , Schulz S. , Basu A. , Beck R. , Brüggen M. , Dettmar R.-J. , Stein M. , Gajović L. , Tabatabaei F. S. , Reichherzer P. 
Published: January 2023

Context. The details of cosmic-ray transport have a strong impact on galaxy evolution. The peak of the cosmic-ray energy distribution is observable in the radio continuum using the electrons as proxy.
Aims. We aim to measure the distance that the cosmic-ray electrons (CREs) are transported during their lifetime in the nearby galaxy M 51 across one order of magnitude in cosmic-ray energy (approximately 1–10 GeV). To this end, we use new ultra-low frequency observations from the LOw Frequency ARay (LOFAR) at 54 MHz and ancillary data between 144 and 8350 MHz.
Methods. As the CREs originate from supernova remnants, the radio maps are smoothed in comparison to the distribution of the star formation. By convolving the map of the star formation rate (SFR) surface density with a Gaussian kernel, we can linearise the radio–SFR relation. The best-fitting convolution kernel is then our estimate of the CRE transport length.
Results. We find that the CRE transport length increases at low frequencies, as expected since the CRE have longer lifetimes. The CRE transport length is lCRE = √4Dtsyn, where D is the isotropic diffusion coefficient and tsyn is the CRE lifetime as given by synchrotron and inverse Compton losses. We find that the data can be well fitted by diffusion, where D = (2.14 ± 0.13)×1028 cm2 s−1. With D ∝ E0.001 ± 0.185, the diffusion coefficient is independent of the CRE energy E in the range considered.
Conclusions. Our results suggest that the transport of GeV-cosmic ray electrons in the star-forming discs of galaxies is governed by energy-independent diffusion.