bluuebunny/crossref_metadata_2025_split huggingface dataset:
Barking up the wrong tree: the importance of morphology in plant molecular phylogenetic studies
Authors: Almeida Rafael Felipe , Cheek Martin , Pellegrini Marco , de Morais Isa Lucia , Simão-Bianchini Rosangela , Rattanakrajang Pantamith , Simões Ana Rita 
Published: February 2023

Background and aims &ndash; Keraunea is a genus recently described in Convolvulaceae, though it has sat uncomfortably in this family. A recent molecular phylogenetic study suggests that its two morphologically almost identical species actually belong to different families, Malpighiaceae (Superrosids) and Ehretiaceae (Superasterids), although with little-to-no morphological evidence to support it.
Material and methods &ndash; Sequences of matK, rbcL, and ITS for all the 77 currently accepted genera of Malpighiaceae, K. brasiliensis and Elatinaceae (outgroup) were compiled from Genbank and analysed with Maximum Likelihood and Bayesian Inference criteria for nuclear, plastid and combined datasets. Additional database and herbarium studies were performed to locate and analyse all duplicates of the holotype of K. brasiliensis to check for misidentified or contaminated materials.
Key results &ndash; Our examination of expanded DNA datasets and herbarium sheets of all K. brasiliensis isotypes revealed that an error in tissue sampling was, in fact, what led to this species being placed in Malpighiaceae. Kew&rsquo;s isotype had a leaf of Malpighiaceae (likely from Mascagnia cordifolia) stored in the fragment capsule, which was unfortunately sampled and sequenced instead of the actual leaves of K. brasiliensis.
Conclusions &ndash; DNA sequences can be helpful in classifying taxa when morphology is conflicting or of a doubtful interpretation, with molecular phylogenetic placement becoming a popular tool that potentially accelerates the discovery of systematic relationships. However, good knowledge of plant morphology is essential for formulating the phylogenetic hypotheses to be tested and for a critical re-interpretation of the results in the context of biological information of the species or families. Thus, these techniques are, much like any others, prone to methodological errors. We highlight the crucial need to observe plant morphology alongside molecular phylogenetic results, particularly when the new hypotheses are in disagreement with the existing classification and at risk of incurring gross taxonomic mistakes.
Vascular plants of old cemeteries in the Lower Dnipro region (Southern Ukraine)
Authors: Skobel Nadiia , Moysiyenko Ivan , Sudnik-Wójcikowska Barbara , Dembicz Iwona , Zachwatowicz Maria , Zakharova Maryna , Marushchak Oleksii , Dzerkal Vikroria 
Published: February 2023

The dataset contains the records of vascular plant species occurrences and distribution in old cemeteries (OC) of the Lower Dnipro region (Southern Ukraine). The analysed cemeteries were located in different types of landscapes (agricultural, rural and urban) and represent various ways of using their area (currently used, closed, abandoned). The floristic list includes 440 species of vascular plants (437 in situ, 3 ex situ). The dataset demonstrates a sozological (Red-lists species) value of old cemeteries in Southern Ukraine. The cemeteries constitute refuges of native, rare and steppe flora and play a role of steppe habitat islands in a landscape almost completely transformed to arable land or urbanised.
This is the first dataset which contains information about flora of old cemeteries in Lower Dnipro region (Southern Ukraine). The dataset comprises 2118 occurrences of vascular plants (440 species) recorded in the years 2008-2021 in 13 old cemeteries of the Lower Dnipro region. The dataset includes information about 85 occurrences of rare species (23 species in situ, 3 ex situ) and 652 occurrences of 117 steppe species.
Clinimetric Validation of the Assessment of Spondyloarthritis International Society Health Index in Patients With Radiographic Axial Spondyloarthritis in Ixekizumab Trials
Authors: Kiltz Uta , van der Heijde Désirée , Boonen Annelies , Gensler Lianne S. , Gibble Theresa Hunter , Guo Jiaying , Carlier Hilde , Braun Juergen 
Published: February 2023

ObjectiveTo assess test-retest reliability, construct validity, known groups discrimination, and responsiveness of the Assessment of the SpondyloArthritis international Society Health Index (ASAS HI) to evaluate functioning, disability, and health in patients with radiographic axial spondyloarthritis (r-axSpA).MethodsData were generated from 2 randomized, placebo-controlled, active-controlled phase III ixekizumab studies (COAST-V, N = 341; COAST-W, N = 316). Assessments included the following: test-retest reliability (ie, intraclass correlation coefficients [ICCs] between ASAS HI scores at screening and baseline), construct validity (ie, Spearman correlation with standard r-axSpA outcome measures), known groups discrimination (ie, 1-way ANOVA comparing the ASAS HI with different disease activity categories, measured by the Ankylosing Spondylitis Disease Activity Score [ASDAS]), and responsiveness (ie, Spearman correlation between changes in the ASAS HI and changes in the Bath Ankylosing Spondylitis Functional Index [BASFI], the Bath Ankylosing Spondylitis Disease Activity Index [BASDAI], the ASDAS, and the Patient Global Assessment [PtGA] as well as ANOVA comparing changes in the ASAS HI with various responder categories).ResultsThe ICC for test-retest reliability was 0.78 for COAST-V and 0.76 for COAST-W, indicating adequate agreement. Moderate-to-large correlations (r= 0.40-0.61) were observed between the ASAS HI and the BASDAI. Statistically significant differences (allP< 0.001) between mean ASAS HI scores were observed for subgroups based on ASDAS-defined disease activity categories at baseline and week 16. Moderate-to-large correlations existed between changes in the ASAS HI and the BASFI, BASDAI, ASDAS, and PtGA from baseline to week 16. The ASAS HI differentiated statistically (P< 0.001) between ASAS, BASDAI, and ASDAS response groups.ConclusionThe ASAS HI demonstrated reliability, construct validity, known groups discrimination, and responsiveness in adults with r-axSpA in 2 clinical trials.
The Effects of Continuity of Rheumatology Care on Emergency Department Utilization and Hospitalizations for Individuals With Early Rheumatoid Arthritis: A Population-Based Study
Authors: Davtyan Abel , Lee Jennifer J.Y. , Eder Lihi , Hawker Gillian A. , Luo Jin , Barber Claire E.H. , Thorne J. Carter , Widdifield Jessica 
Published: February 2023

ObjectiveTo determine if continuity of rheumatology care influences rates of emergency department (ED) visits and hospitalizations in patients with rheumatoid arthritis (RA).MethodsA closed inception cohort of patients with RA diagnosed between 2000 and 2009 were followed until December 31, 2019. During the first 5 years following diagnosis, we categorized patients into 3 rheumatology care continuity groups (high, intermediate, and not retained in rheumatology care). Using a landmark analysis, we compared rates of ED visits and hospitalizations during follow-up. Multivariable Poisson regression models were used to estimate rate ratios (RRs), adjusting for demographics, comorbidities, and health services access and supply measures.ResultsThe cohort included 38,528 patients, of which 57.7% (n = 22,221) were classified in the high rheumatology continuity group, 17.2% (n = 6636) were in the intermediate group, and 25.1% (n = 9671) were not retained in rheumatology care. Relative to the high continuity group, both the intermediate and nonretention groups had higher ED rates (RR 1.14, 95% CI 1.08-1.20, and RR 1.12, 95% CI 1.08-1.16, respectively). The intermediate group also experienced higher adjusted hospitalization rates (207.4, 95% CI 203.0-211.8 per 1000 person-years [PY]) than the high continuity group (193.5, 95% CI 191.4-195.6 per 1000 PY).ConclusionPatients with RA with higher continuity of rheumatology care had lower rates of ED visits and hospitalizations compared to those who did not receive continuous rheumatology care during the first 5 years of follow-up. These findings provide evidence to support the value of early and continuous rheumatology care for reducing hospitalizations and ED visits.
La protection des navires de passagers en France
Authors: Latour Xavier 
Published: February 2023

Résumé : La croisière ne présente pas seulement un enjeu économique, elle est aussi un enjeu de sécurité intérieure. Les navires de passagers sont des cibles très exposées, sans doute autant que les avions. C’est pourquoi l’État mobilise d’importants moyens pour prévenir les menaces et y répondre. Comme il ne peut pas agir seul, il compte également sur les renforts de la sécurité privée. Des agents armés peuvent ainsi être embarqués.
« Sentio ergo sum » : le chiffre cartésien du sens illatif chez John Henry Newman
Authors: Solari Grégory 
Published: February 2023

Le Journal philosophique de John Henry Newman propose une figure « pathique » du Cogito cartésien. « Je pense donc je suis » doit s’entendre non comme la conséquence du fait de penser mais comme la dispense du mode de penser reposant sur l’inférence. Dans la lecture de Newman, cette dispense se traduit par la « suspension » de ergo dans le cogito . « Cogito ergo sum » devient « sentio ergo sum » – « je sens donc je suis ». L’épistémologie de Newman fait fond sur une affection. C’est l’esprit ( noûs ) qui « sent ». Une auto-affection atteste immédiatement l’existence du moi : c’est le cogito quand il est compris comme sentio , sentir. Une hétéro-affection atteste l’existence de Dieu : c’est la conscience comme phénomène ressenti à la limite de l’immanence.
« Newman vous mettra à l’aise ». Réflexions sur une invitation faite à Bergson
Authors: Waterlot Ghislain 
Published: February 2023

Avec la publication des Deux Sources de la morale et de la religion , il apparut que Bergson s’était très fortement rapproché du christianisme. Allait-il se convertir au catholicisme ? La question était posée. Ses amis catholiques lui ont conseillé la lecture du cardinal Newman, en tant qu’auteur d’une pensée qui, introduisant la notion de « développement » du dogme, pouvait l’incliner à reconnaître une compatibilité de sa philosophie avec la théologie catholique telle qu’elle se comprenait désormais et lever ainsi les obstacles mis sur le chemin par la « crise moderniste ». Cet essai tend à montrer que les difficultés étaient plus profondes que ne le pensaient les amis de Bergson, dans la mesure où le rapport entre le dogme et la vérité n’est en fait pas pensé de la même façon chez le cardinal britannique et chez le philosophe français.
« Lumière réflexe » et « sens illatif » : John Henry Newman et la Grammaire de l’assentiment
Authors: Rabourdin David 
Published: February 2023

Dans la Grammaire de l’assentiment , lors de son investigation des facultés humaines et de leur jeu dans la recherche de la vérité, Newman se place sous l’éclairage d’une « lumière réflexe », qui lui permet d’affirmer le « sens illatif » comme unique lien entre inférence et assentiment. Cette « lumière » introduit une perspective théologique au cœur de son investigation philosophique. Ainsi, Newman affirme à la fois le dynamisme de l’esprit humain dans son chemin vers la vérité, le caractère libre et personnel de ce chemin, et la présence de la Providence divine à chaque étape de cette recherche.
Sentence matrimoniale pro nullitate erronée et secondes noces canoniques : un apax juridique à la suite de la faculté II du 11 février 2013
Authors: Danto Ludovic 
Published: February 2023

Le mariage jouit de la faveur du droit. Tout mariage est indissoluble et seule la fin de celui-ci permet de passer à de secondes noces. Dans le cas contraire, tout consentement est naturellement suffisant mais juridiquement inefficace. Or, les facultés du 11 février 2013 concédées à la Rote romaine par le pape Benoît XVI remettent en cause ce principe : il est possible de reconnaître des secondes noces malgré l’éventuel empêchement de lien préexistant. La position catholique rejoindrait par cet apax juridique la position orthodoxe.
Awake Prone Positioning in Nonintubated Patients With Acute Hypoxemic Respiratory Failure
Authors: Fusi Cristian , Bulleri Enrico , Villa Michele , Pisani Luigi , El Aoufy Khadija , Lucchini Alberto , Bambi Stefano 
Published: February 2023

Background
Awake prone positioning research focuses primarily on improving oxygenation and reducing intubation and mortality rates. Secondary outcomes concerning patient safety have been poorly addressed.

Objective
To summarize current evidence on the frequency of adverse events during awake prone positioning and the effects on patients’ safety, comfort, and tolerance.

Methods
This scoping review used the Preferred Reporting Items for Systematic Reviews and Meta-analyses Extension for Scoping Reviews. MEDLINE/PubMed and CINAHL databases were the primary sources for the systematic search.

Results
The review included 19 original studies involving 949 patients who underwent awake prone positioning. No major complications such as death, severe respiratory compromise, or hemodynamic disease were reported. Ten studies reported the following secondary adverse events related to awake prone positioning: skin breakdown (1%-6% of patients), pain (12%-42%), discomfort (35%-43%), vomiting (2%-7%), intolerance (3%-47%), and vascular catheter dislodgment (5%). The duration of awake prone positioning sessions varied widely (0.3-19 hours). Seven studies reported that nurses helped patients during prone positioning maneuvers, including monitoring and surveillance, and 3 studies reported patients placing themselves in the prone position. In 6 studies light or moderate sedation was employed in the procedures.

Conclusions
Awake prone positioning was not related to cardiorespiratory consequences but was associated with pain, intolerance, discomfort, and patients’ refusal. Patients should receive education regarding awake prone positioning to improve their acceptance. Health care professionals should optimize pain control, communication, patient comfort, patient adherence, and correct positioning.
Paroxysmal Sympathetic Hyperactivity After Acquired Brain Injury: An Integrative Literature Review
Authors: Seo WhaSook 
Published: February 2023

Background
Paroxysmal sympathetic hyperactivity may occur in patients with acute brain injury and is associated with physical disability, poor clinical outcomes, prolonged hospitalization, and higher health care costs.

Objective
To comprehensively review current literature and provide information about paroxysmal sympathetic hyperactivity for nurses.

Methods
An integrative literature review was conducted according to Whittemore and Knafl’s method. The search was conducted from October 2020 through January 2021. The main targets of the literature search were definition, incidence rate, causes, clinical characteristics, pathophysiology, diagnosis, and treatment of paroxysmal sympathetic hyperactivity in pediatric and adult patients. The results were reported using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.

Results
The most characteristic clinical features of paroxysmal sympathetic hyperactivity are hypertension, tachycardia, tachypnea, hyperthermia, diaphoresis, and abnormal motor posturing. Reported incidence rates of paroxysmal sympathetic hyperactivity in patients with brain injury range from 8% to 33%. Various diagnostic criteria have been proposed; most are based on clinical symptoms. Ruling out other causes of the signs and symptoms of paroxysmal sympathetic hyperactivity is important because the signs and symptoms are nonspecific. The major goals of paroxysmal sympathetic hyperactivity management are avoidance of stimuli that may trigger a paroxysmal episode, inhibition of sympathetic overactivity, and prevention of damage to other organs.

Conclusions
Critical care nurses should be aware of the signs and symptoms of paroxysmal sympathetic hyperactivity in patients with acute brain injury. Early identification is important to ensure timely treatment for patients with paroxysmal sympathetic hyperactivity.
MicroRNAs in Macrophages: Regulators of Activation and Function
Authors: Sprenkle Neil T , Serezani C Henrique , Pua Heather H 
Published: February 2023

Abstract
Macrophages are sentinels of the innate immune system that maintain tissue homeostasis and contribute to inflammatory responses. Their broad scope of action depends on both functional heterogeneity and plasticity. Small noncoding RNAs called microRNAs (miRNAs) contribute to macrophage function as post-transcriptional inhibitors of target gene networks. Genetic and pharmacologic studies have uncovered genes regulated by miRNAs that control macrophage cellular programming and macrophage-driven pathology. miRNAs control proinflammatory M1-like activation, immunoregulatory M2-like macrophage activation, and emerging macrophage functions in metabolic disease and innate immune memory. Understanding the gene networks regulated by individual miRNAs enhances our understanding of the spectrum of macrophage function at steady state and during responses to injury or pathogen invasion, with the potential to develop miRNA-based therapies. This review aims to consolidate past and current studies investigating the complexity of the miRNA interactome to provide the reader with a mechanistic view of how miRNAs shape macrophage behavior.
Diagnostic value of LungPoint navigation combined with EBUS-GS & ROSE in peripheral pulmonary nodules
Authors: Zhang Qun-Cheng , Xuan Wei-Xia , Li Hui-Li , Sun Guan-Nan , Cheng Dong-Jun , Wang Zheng , Yong-Qi  , Zhang Xiao-Ju 
Published: February 2023

Background & objectives:
Recently, there has been a surge to develop new devices and techniques for the diagnosis of peripheral pulmonary lesions such as the combination of LungPoint navigation and endobronchial ultrasound with a guide sheath (EBUS-GS). The present study aimed to explore the diagnostic value of LungPoint navigation in combination with EBUS-GS and rapid on-site evaluation (ROSE) particularly for peripheral pulmonary nodules.

Methods:
Patients (n=108) with pulmonary nodules (10 mm ≤ nodal diameter ≤30 mm) presenting to Henan Provincial People’s Hospital were detected using chest computed tomographic (CT) scanning and bronchoscopy. All patients were evaluated using LungPoint navigation, EBUS-GS and ROSE techniques to evaluate the positive rate of combined diagnosis using the three methods.

Results:
A total of 108 patients participated in this study and successfully underwent all the three procedures. Of these, 82 patients were accurately diagnosed, making the overall diagnostic rate of 75.9 per cent for combined LungPoint navigation, EBUS-GS, and ROSE analyses. Further subgroup analysis of the diagnostic rate of the three combined techniques were conducted based on the size of the nodules which showed a diagnostic rate of 65.3 per cent for 10 mm ≤ nodule diameter ≤20 mm and 85.7 per cent for 20 mm ≤ nodal diameter ≤30 mm. Of the 108 patients, 85 had solid nodules and 23 had ground-glass nodules; the positive rate of diagnosis of solid nodules was the highest. The patients ultimately were diagnosed with lung cancer with a positive rate of 83.5 per cent. The sensitivity, specificity and positive and negative predicted values for ROSE were 90.3, 78.3, 84.8 and 83.6 per cent, respectively.

Interpretation & conclusions:
The combined use of the three techniques can effectively shorten the duration of the total diagnosis period and improve the safety of diagnosis without affecting the detection rate.
Cone-Beam-Computed Tomography Evaluation of Mandibular Nutrient Canals in Patients with Periodontal Diseases*
Authors: Tumer H , Orhan K , Aksoy S , Berberoglu A 
Published: February 2023

Background and Aim:
The aim of this study was to evaluate radiographically the prevalence of mandibular nutrient canals (NCs) in patients with/without periodontal bone loss with aging and to correlate the number of NCs with the severity of bone loss using cone-beam-computed tomography (CBCT).

Patients and Methods:
CBCT examinations of 208 patients were evaluated retrospectively of all patients, 114 had periodontal bone loss, whereas 94 patients were control subjects. Alveolar bone loss investigations were performed according to the Progressive Rate Index.

Results:
NCs were observed in 55% of the control group and 86% of the periodontitis patients. NCs were more prevalent in the elderly age group with periodontal bone loss. In the study group, the NCs were statistically more frequent than in the control subjects (P > 0.05).

Conclusion:
Statistical analysis showed a significant difference between the age groups and the prevalence of NCs increased in patients with periodontal alveolar bone loss with aging (P < 0.05).
Graphene on Dentistry: A Bibliometric and Scientometric Analysis
Authors: Erdinç G 
Published: February 2023

Background:
Today, the development of dental materials is a very important issue. Graphene has been used in dentistry to strengthen many materials.

Aim:
The aim of this study was to analyze leading countries and to identify the preferred journals, the most commonly used keywords, and the most productive authors in the field of graphene.

Materials and Methods:
The search keyword was “graphene” on the Web of Science database; the search was restricted to before 2022. The selected search from the Web of Science database included the title of articles, authors, year of publication, country, citation count, and keywords. An analysis was performed regarding citations and documents, authors, journals, and keywords using a bibliometric software program. All articles were evaluated and subjected to scientometric analysis.

Results:
Twenty six articles were included in the study. There has been a remarkable increase in published articles from past to present, and a regular increase is observed in the number of citations. Dental Materials has highest number of publications among the articles included in the present study. Dr. Rosa, who had the highest number of citations, is also the most effective author. Graphene has many studies in dentistry with different materials. As per the data obtained, graphene, graphene oxide, and peri-implantitis are the most used keywords and Singapore and China are at the forefront of the countries where the articles are published.

Conclusion:
This bibliometric analysis reveals the progress and trend of research on graphene in dentistry and extensive collaborations between authors, countries, and institutions. The findings of this study can help inspire researchers to plan new studies and collaborate on graphene.
Utilization of Eye Care Services in an Underserved Community in Enugu State, Nigeria
Authors: Ezinne NE , Ekemiri KK , Chukwuma I , Ojukwu CS , Mashige KP , Ilechie AA , Moyo G 
Published: February 2023

Background and Aim:
To determine the utilization of eye care services in an underserved community in Enugu State, Nigeria.

Materials and Methods:
A community-based cross-sectional study was conducted among adults aged 18 years and older. A structured questionnaire was used to collect information on the utilization of eye care services within the last two years.

Result:
A total of 500 adults with a mean age of 48 ± 10 years participated in the study, the majority (65.6%) of whom were females. The utilization rate within the last two years was 18% (40/500). Utilization of eye care services was associated with age, religion, occupation, marital status, monthly income, education, family history, and history of ocular disease (all P < 0.05). The major barrier to the utilization of eye care services was cost (30%), distance (22.6%), and bad road infrastructure (15.2%).

Conclusion:
There is a low rate of eye care service utilization in the Ugbawka community of Enugu State, Nigeria. The cost of eye care services, distance, and bad road infrastructure were the major barriers to the use of eye care services. These suggest the need for the provision of affordable and accessible eye care services in this community to reduce the burden of visual impairment and blindness.