bluuebunny/crossref_metadata_2025_split huggingface dataset:
Implementing the DSM‐5 parent/guardian‐rated level 1 cross‐cutting symptom measure child 6−17 in a community mental health clinic
Authors: Corbel Hervé , Kinchen Elizabeth 
Published: August 2023

AbstractProblemDespite their relevance to assessment and clinical decision‐making in behavioral health, measurement tools are still rarely used in clinical settings. With an increase in undiagnosed and untreated mental health problems in children and adolescents, a southeastern US Community Health System was the ideal setting for the implementation of a behavioral health assessment tool.MethodsThis quality improvement project was conducted to address the question: “Among mental health clinicians at the Community Health System, will the use of the DSM‐5 parent/guardian‐rated level 1 cross‐cutting symptom measure 6−17 (CCSM) improve diagnosis and treatment choices of children with mental health conditions, over a 4‐week period?” A convenience sample was recruited from among behavioral health counselors working at various out‐patient clinics and school‐based counseling sites in the Community Health System. After nurse‐led training on use of the CCSM, including a PowerPoint intervention and individual coaching sessions, the five clinical participants were encouraged to use the CCSM screening tool on their patients presenting for mental health assessment. Knowledge of the tool was assessed using a pre‐ and post‐training survey. Completed screening tools were collected from participants over the 4‐week duration of the project.FindingsA chart audit comparing the project period with the previous year showed an increase in diagnosis and treatment in 6−17 year‐old patients at the outpatient clinic.ConclusionsThis project demonstrated the usefulness of the CCSM for behavioral health assessment in the child/adolescent population at the Community Health System and supported use of the intervention in other clinics.
COVID outcome in pemphigus: Does rituximab make pemphigus patients susceptible to more severe COVID‐19?
Authors: Aryanian Zeinab , Balighi Kamran , Sajad Baseerat , Esmaeli Nafiseh , Daneshpazhooh Maryam , Mazloumi Tootoonchi Nasim , Beigmohammadi Fereshteh , Mohseni Afshar Zeinab , Hatami Parvaneh 
Published: August 2023

AbstractBackgroundThe COVID‐19 pandemic has raised some concerns regarding the management of chronic skin diseases, especially in patients on immunosuppressive therapy including patients with pemphigus vulgaris (PV). Literature review reveals conflicting results about the effect of monoclonal antibodies such as rituximab on clinical outcome of COVID‐19.ObjectivesTo assess the reciprocal interaction of COVID‐19 and pemphigus and the effect of rituximab on prognosis of COVID‐19 in patients.MethodsWe set up a retrospective study on adult patients with a confirmed diagnosis of pemphigus vulgaris and a history of COVID‐19 with or without symptoms during 2020.ResultsThirty‐six adults with pemphigus vulgaris and SARS‐CoV‐2 infection were included. The SARS‐CoV‐2 infection was confirmed with positive RT‐PCR test results in 31 cases (86.1%) and suspected in the 5 others (13.9%). Gender, total dose of rituximab, number of rituximab cycles, and involvement of head and neck were not associated to duration of COVID‐19 symptoms (p values: 0.32, 0.23, 0.84, and 0.51, respectively), severity of disease (hospitalization) (p values: 0.46, 0.39, 0.23, and 0.72, respectively), or the percentage of lung involvement on CT scan (p values: 0.07, 0.36, 0.38, and 0.09, respectively). Regarding the impact of COVID‐19 on pemphigus, the majority of patients did not experience any changes in their pemphigus regarding clinical phenotype (100%) or severity (83.3%), but PV was worsened in 6 (16.9%) patients which was controlled with increasing the prednisolone dosage.ConclusionRituximab appears to be safe with no increased risk of severe form of COVID‐19 in patients with pemphigus vulgaris.
Elevated translationally controlled tumour protein promotes oral cancer progression and poor outcome
Authors: Sharma Dipti , Pawar Sagar N. , Sulkshane Prasad , Waghole Rohit , Yasser Mohd , Pawar Sushil S. , Kannan Sadhana , Chaudhary Nazia , Kalwar Anjali , Patil Rahul , Nair Sudhir , Dalal Sorab N. , Teni Tanuja 
Published: August 2023

AbstractBackgroundTranslationally controlled tumour protein (TCTP) is a multifunctional protein elevated in multiple cancers. However, studies on its role in oral carcinogenesis and prognosis are rare. We recently reported the role of its interacting partner, MCL1, in oral cancer progression and outcome. Hence, the present study aimed to assess TCTP expression in oral tumorigenesis and its association with patient outcomes alone and in combination with MCL1.MethodsTCTP expression was assessed by immunohistochemistry and immunoblotting in oral tissues and cells, respectively. Cell viability post siRNA/dihydroartemisinin treatment was analysed by tetrazolium salt assay. Cell survival, invasion and tumorigenic potential post TCTP knockdown were assessed by clonogenic, Matrigel and soft‐agar assays, respectively. The association of TCTP with patient outcome was analysed by Kaplan–Meier and Cox regression.ResultsTCTP was significantly overexpressed in oral premalignant lesions (p < 0.0001), oral tumours (p < 0.0001) and oral dysplastic and cancer cells versus normal oral mucosa and also in recurrent (p < 0.05) versus non‐recurrent oral tumours. Further, elevated TCTP was significantly (p < 0.05) associated with poor recurrence free survival (RFS) and poor overall survival (OS; hazard ratio = 2.29; p < 0.05). Intriguingly, the high co‐expression of TCTP and MCL1 further reduced the RFS (p < 0.05) and OS (p < 0.05; hazard‐ratio = 3.49; p < 0.05). Additionally, TCTP knockdown decreased survival (p < 0.05), invasion (p < 0.01) and in vitro tumorigenic potential (p < 0.0001). Dihydroartemisinin treatment reduced TCTP levels and viability of oral cancer cells.ConclusionOur studies demonstrate an oncogenic role of TCTP in oral cancer progression and poor outcome. Thus, TCTP may be a potential prognostic marker and therapeutic target in oral cancers.
Impact of chronic kidney disease on everyday life: A descriptive qualitative study
Authors: Yapa Harith Eranga , Chambers Shirley , Purtell Louise , Bonner Ann 
Published: August 2023

AbstractBackgroundLiving with chronic kidney disease is stressful as the disease and its treatments impact on everyday physical, psychological, and social activities. As this disease has a long trajectory, it is important to understand everyday life experiences of those at different points along this trajectory.ObjectivesTo explore the impact of chronic kidney disease and its treatment on everyday life.DesignDescriptive qualitative designParticipantsTwenty‐five adults with chronic kidney disease across various grades were purposively recruited.ApproachData were collected using semistructured interviews. Deductive content analysis informed by the revised Wilson and Cleary model was used to analyse data.FindingsThere were four themes. Theme 1, experiencing deterioration of kidney function, reflected the physical and psychological problems experienced by participants. Theme 2, changes that happened to me and my family, explained the subsequent limitations in their physical, social and role functioning. Theme 3, responding to a new normal, identified adjustments needed in everyday life to cope with the disease and its treatments. The final theme, thinking ahead and making a decision, captured the future plans and decisions needed while living with chronic kidney disease.ConclusionsPeople with chronic kidney disease experience complex challenges such as greater symptom burden and functional limitations across the disease grades which impact on their everyday life. Nurses' recognition of these challenges is crucial for identifying and addressing unmet needs. Early individualised interventions, such as routine symptom assessment and management strategies that improve the wellbeing of people are needed.
Using the consensus group method to select the best screening tools for autism and intellectual disability for use with Nigerian adolescents
Authors: Nwokolo Eziafakaku Uchechukwu , Murphy Glynis H. , Mensink Anne‐Marie , Moonen Xavier , Langdon Peter E. 
Published: August 2023

AbstractDiagnosing autism or ID using a gold‐standard tool can be time‐consuming, costly, and requires training, which is generally limited in Nigeria, and the rest of Africa. Screening, on the other hand, can be quick and effective, with minimal training depending on the tool (Iragorri & Spackman, Public Health Reviews, 2018;39(1):17), thus making the availability of short screeners a necessity in Nigeria, and the rest of Africa. We identified four screening tools through a previously completed systematic review (Nwokolo et al., Review Journal of Autism and Developmental Disorders, 2022;1–23.), two (SCQ and AQ‐10) for autism and two (SCIL and CAIDS‐Q) for ID, which appeared appropriate for validation for use within African nations. The Nominal Group Technique was used with a purposive group of professionals, parents, and laypersons to select and adapt the existing screening tools for autism and ID for use with older children and adolescents in Nigeria. The group examined the screening tools for cultural relevance, face and content validity. Following the discussions, items were either (1) accepted in the original form or (2) more culturally appropriate examples chosen if at least 75% of participants agreed. The group selected the SCQ for autism and the SCIL for ID. The minimum agreement on all autism and ID measures items was 84%, and this indicated the measures had face and content validity for use within Nigeria. Following the recommendations and consensus of the group, the SCQ and the SCIL 14–17 were agreed on as measures to be validated with the Nigerian adolescents, with only a small number of adjustments needed to allow for different use of language, customs and environment in the Nigerian context.
Chinese expert consensus on the construction of the fluoroless cardiac electrophysiology laboratory and related techniques
Authors: Jiang Chenyang , Ma Changsheng , Chen Songwen , Chen Shiquan , Jiang Chenxi , Jiang Ruhong , Ju Weizhu , Long Deyong , Li Ding , Li Jia , Liu Qiang , Ma Wei , Pu Xiaobo , Wang Rui , Wang Yuegang , Yi Fu , Zou Cao , Zhang Jidong , Zhang Xi , Zhao Yujie , Zei Paul C. , Biase Luigi Di , Chang Dong , Cai Heng , Chen Lianghua , Chen Minglong , Fu Guosheng , Fu Hua , Fan Jie , Gui Chun , Jiang Tingbo , Liu Shaowen , Li Xuebin , Li Yigang , Shu Maoqin , Wang Yan , Xu Jian , Xie Ruiqin , Xia Yunlong , Xue Yumei , Yang Pingzhen , Yuan Yiqiang , Zhong Jingquan , Zhu Wenqing 
Published: August 2023

AbstractTranscatheter radiofrequency ablation has been widely introduced for the treatment of tachyarrhythmias. The demand for catheter ablation continues to grow rapidly as the level of recommendation for catheter ablation. Traditional catheter ablation is performed under the guidance of X‐rays. X‐rays can help display the heart contour and catheter position, but the radiobiological effects caused by ionizing radiation and the occupational injuries worn caused by medical staff wearing heavy protective equipment cannot be ignored. Three‐dimensional mapping system and intracardiac echocardiography can provide detailed anatomical and electrical information during cardiac electrophysiological study and ablation procedure, and can also greatly reduce or avoid the use of X‐rays. In recent years, fluoroless catheter ablation technique has been well demonstrated for most arrhythmic diseases. Several centers have reported performing procedures in a purposefully designed fluoroless electrophysiology catheterization laboratory (EP Lab) without fixed digital subtraction angiography equipment. In view of the lack of relevant standardized configurations and operating procedures, this expert task force has written this consensus statement in combination with relevant research and experience from China and abroad, with the aim of providing guidance for hospitals (institutions) and physicians intending to build a fluoroless cardiac EP Lab, implement relevant technologies, promote the standardized construction of the fluoroless cardiac EP Lab.
Atrial paced rhythm and heart rate‐dependent worsening of left atrial and ventricular function
Authors: Corbo Maria Delia , Terlizzi Vito di , Barone Roberta , Pellegrino Pierluigi , Goffredo Giovanni , Pugliese Rosanna , Correale Michele , Ieva Riccardo , Di Biase Matteo , Brunetti Natale Daniele , Iacoviello Massimo 
Published: August 2023

AbstractBackground and aim of the studyThe response to the increase in heart rate (HR) could be characterized by failure in both left ventricular (LV) and left atrial (LA) functions. This study aimed to evaluate the relationship between the increase in paced HR and the changes in LV and LA functions, assessed by two‐dimensional speckle tracking analysis.MethodsIn a group of patients with an implantable cardioverter defibrillator (ICD) or pacemaker, the atrial paced rhythm was progressively increased from 60 to 70, from 70 to 80, and from 80 to 90 beats per minute (bpm). For each paced HR, using two‐dimensional speckle tracking analysis, LA reservoir (LAr), LA conduit (LAc), LA contraction (LAct), and LV global longitudinal strain (LV‐GLS) were evaluated every 10 bpm.ResultsOf the 45 patients enrolled, a significant reduction in LAr was observed at higher HR. However, when the patients were dichotomized according to the HR‐related response of LV‐GLS, the worsening of LAr was observed in those with LV‐GLS worsening and not in those without (maximum LAR absolute changes −2.7 ± 7.2% vs. +2.7 ± 7.2%, respectively, p .028). Moreover, the worsening of LA and LV strain measures was associated with an increase in the estimated filling pressures.ConclusionsIn patients with atrial paced rhythm, the increase in HR could be associated with worsening of LA and LV functions, as assessed by two‐dimensional speckle tracking analyses. These results offer new data on HR‐related atrioventricular function and could be useful for guiding the optimal HR responsiveness of the implanted devices.
A survey on conventional and learning‐based methods for multi‐view stereo
Authors: Stathopoulou Elisavet Konstantina , Remondino Fabio 
Published: August 2023

Abstract3D reconstruction of scenes using multiple images, relying on robust correspondence search and depth estimation, has been thoroughly studied for the two‐view and multi‐view scenarios in recent years. Multi‐view stereo (MVS) algorithms aim to generate a rich, dense 3D model of the scene in the form of a dense point cloud or a triangulated mesh. In a typical MVS pipeline, the robust estimations for the camera poses along with the sparse points obtained from structure from motion (SfM) are used as input. During this process, the depth of generally every pixel of the scene is to be calculated. Several methods, either conventional or, more recently, learning‐based have been developed for solving the correspondence search problem. A vast amount of research exists in the literature using local, global or semi‐global stereomatching approaches, with the PatchMatch algorithm being among the most popular and efficient conventional ones in the last decade. Yet, and despite the widespread evolution of the algorithms, yielding complete, accurate and aesthetically pleasing 3D representations of a scene remains an open issue in real‐world and large‐scale photogrammetric applications. This work aims to provide a concrete survey on the most widely used MVS methods, investigating underlying concepts and challenges. To this end, the theoretical background and relative literature are discussed for both conventional and learning‐based approaches, with a particular focus on close‐range 3D reconstruction applications.
The Dworkin–Williams debate: Liberty, conceptual integrity, and tragic conflict in politics
Authors: Queloz Matthieu 
Published: August 2023

AbstractBernard Williams articulated his later political philosophy notably in response to Ronald Dworkin, who, striving for coherence or integrity among our political concepts, sought to immunize the concepts of liberty and equality against conflict. Williams, doubtful that we either could or should eliminate the conflict, resisted the pursuit of conceptual integrity. Here, I reconstruct this Dworkin–Williams debate with an eye to drawing out ideas of ongoing philosophical and political importance. The debate not only exemplifies Williams's political realism and its connection to his critique of the morality system. It also illustrates the virtues and hazards of contemporary efforts to ameliorate or engineer our concepts; it indicates what political philosophy might look to in appraising political concepts; it adverts to the different needs these concepts have to meet if they are to sustain a politics of pluralism, deal with polarization, and secure the consent of those who end up on the losing side of political decisions; and it presents us with two starkly contrasting conceptions of politics itself, of the place of political values within it, and of our prospects of reducing the uncomfortably conflictual character of those values through philosophy.
Strategies to improve the success of fixed‐time artificial insemination in the ewe
Authors: Weaver Alice C. , Kelly Jennifer M. , Swinbourne Alyce M. , Kleemann David O. , Walker Simon K. 
Published: August 2023

AbstractDuring the sheep breeding season, ovulatory follicles vary widely in age at pessary removal impacting both the timing of oestrus and pregnancy rates following artificial insemination (AI). Ovulatory follicles that emerge between days 7 to 9 of the pessary period are associated with higher fertility whilst those that emerge earlier or later are associated with lower fertility. In this study, two strategies to improve the success of AI by controlling the development of the ovulatory follicle were examined. In the first, ewes were treated with PGF2α at either −12 and/or +6 days (experiment 1) or −27 days (experiment 2) relative to pessary insertion to control the time of emergence of the ovulatory follicle. In the second, ewes were treated with eCG (400 IU per ewe) at either 0 h, −6 h or −12 h relative to pessary removal (experiment 3) to improve the development of young ovulatory follicles. PGF2α administered on day −27 increased the percentage of pregnant ewes by 17.8% and the number of foetuses per 100 ewes inseminated by 33.9%. PGF2α treatment at other times had either no effect or reduced fertility. During the breeding season, treatment with eCG at −12 h improved the synchrony of oestrus, reduced the size of the ovulatory follicle but did not improve pregnancy rate compared with other treatments. Treatment had no effect during the non‐breeding season, supporting earlier findings that the quality of young ovulatory follicles differs during the year. In conclusion, PGF2α treatment 27 days before pessary insertion provides a new and cheap strategy to improve the success of fixed‐time AI programs.
A methodology to estimate postdisaster unmet housing needs using limited data: Application to the 2017 California wildfires
Authors: Costa Rodrigo , Baker Jack W. 
Published: August 2023

AbstractIn the United States, assistance from the Department of Housing and Urban Development (HUD) plays an essential role in supporting the postdisaster recovery of states with unmet housing needs. HUD requires data on unmet needs to appropriate recovery funds. Ground truth data are not available for months after a disaster, however, so HUD uses a simplified approach to estimate unmet housing needs. State authorities argue that HUD's simplified approach underestimates the state's needs. This article presents a methodology to estimate postdisaster unmet housing needs that is accurate and relies only on data obtained shortly after a disaster. Data on the number of damaged buildings are combined with models for expected repair costs. Statistical models for aid distributed by the Federal Emergency Management Agency (FEMA) and the Small Business Administration (SBA) are then developed and used to forecast funding provided by those agencies. With these forecasts, the unmet need to be funded by HUD is estimated. The approach can be used for multiple states and hazard types. As validation, the proposed methodology is used to estimate the unmet housing needs following disasters that struck California in 2017. California authorities suggest that HUD's methodology underestimated the state's needs by a factor of 20. Conversely, the proposed methodology can replicate the estimates by the state authorities and provide accounts of losses, the amount of funding from FEMA and SBA, and the total unmet housing needs without requiring data unavailable shortly after a disaster. Thus, the proposed methodology can help improve HUD's funding appropriation without delays.
Quantitative risk assessment of China's first liquid hydrogen refueling station
Authors: Yuan Wenhao , Li Jingfeng , Yangyiming Rong , Peng Jianbin , Xie Junlong , Chen Jianye 
Published: August 2023

AbstractHydrogen refueling stations (HRSs) are among the most important infrastructures for fuel cell vehicles. However, the safety issue of HRSs has become a key constraint to the wide application and development of hydrogen energy. This article presents a quantitative risk assessment of the first liquid HRS (LHRS) in China and conducts a comprehensive assessment in terms of both individual (IR) and societal risks (SRs). The results showed that both the IRs and SRs related to the LHRS exceeded the risk acceptance criteria. The rupture of the flexible hose of the dispenser and the leak from the compressor are the main contributors to these risks. On the other hand, implementing appropriate mitigation measures on the level of the LHRS dispenser and compressor, including the addition of breakaway couplings in the flexible hose of the dispenser, the installation of hydrogen detection sensors, the arrangement of automatic and manual emergency shutdown buttons, and the elevation of the compressor, is capable of reducing the risk of the LHRS to be within the risk acceptance criteria.
Suspected systemic gas embolism associated with lung tissue perforation caused by a previously inserted chest drain in a dog
Authors: Asorey Iago , Corletto Federico 
Published: August 2023

AbstractObjectiveTo report a case of systemic gas embolism associated with removal of a chest drain perforating a lung lobe in a dog undergoing sternotomy under general anesthesia and intermittent positive pressure ventilation.Case SummaryAn 8‐year‐old Cocker Spaniel underwent an exploratory thoracotomy via median sternotomy for surgical management of pyothorax that was treated conservatively for 7 days prior to referral following bilateral chest drain placement. The surgical procedure consisted of a subphrenic mediastinectomy and pericardiectomy. During surgery, it became apparent that the right drain was perforating the right middle lung lobe. Sudden desaturation and rapid hemodynamic deterioration occurred after the drain was removed. A systemic gas embolism was suspected on the basis of clinical signs and results of an arterial blood gas analysis, and immediate supportive treatment was started with an adequate response. Once the surgical procedure was completed, a clear “mill wheel” sound was audible on cardiac auscultation and point‐of‐care cardiac ultrasound confirmed the presence of gas bubbles in the cardiac chambers. The dog recovered from anesthesia and was managed in the intensive care unit where arterial blood gas analyses were nearly normal and the dog made a full recovery.New or Unique Information ProvidedIn people, there are reports of fatal air embolism related to the use of chest drains. To our knowledge, this is the first case report in dogs of a systemic gas embolism during open‐chest surgery caused by a chest drain perforating a lung lobe. Immediate recognition and aggressive treatment of this life‐threatening condition should be provided in order to achieve a favorable outcome.