bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of blended learning on the adaptation processes of foreign students
Authors: Trukhacheva Nina Vasil'evna , Guseva Anna Vasil'evna , Pupyrev Nikolai Petrovich , Kudrikova Lyudmila Evdokimovna , Leskova Svetlana Sergeevna , Gribova Galina Victorovna 
Published: July 2023

The object of the study are foreign students of ASMU. The purpose of the work is to assess the impact of blended learning on the adaptation of foreign students in Russian universities on the example of ASMU. The subject of the study is the adaptation to the learning process of foreign students in the university environment. An online survey developed based on a set of questions was used to collect data from 80 first-year international students. The analysis of the survey results conducted using the SPSS Statistics program empirically confirms the fact that students' perception of their university learning experience and adaptation were beneficially influenced by the mixed learning environment. The scientific novelty consists in the fact that during the research a questionnaire was developed that allows to determine the general level of adaptation of foreign students to the learning process and to identify the problems that foreign students face more often during their studies in Russia. Based on the results of the survey, practical recommendations are proposed to improve work with foreign students for more successful adaptation in the university environment. Main conclusions 1. The studies conducted at ASMU indicate the positive impact of blended learning (thanks to digital online communication) on the interaction not only of the student and the teacher, but also on the interaction between each other. 2. The results obtained show that blended learning is the means that creates the necessary prerequisites for the emergence of internal motivation of a person's activity, especially when it is able to adapt to the characteristics of the trainees, the level of available knowledge, the pace of assimilation of new knowledge. In this case, students enjoy the learning process, their self-confidence and activity in learning increases. 3. Elements of online learning are organically combined with classroom classes, complementing them and developing self-study skills and providing accessible feedback from the teacher.
Optimization of Machine Parameters for the Peeling of Taro (Colocasia esculenta) Mother Corm in a Commercial Abrasive Peeler
Authors: Nagar Chetan Kumar , Dash Sanjaya Kumar , Rayaguru Kalpana 
Published: July 2023

Aims: The purpose of this study was to optimize the machine parameters of a commercially available tuber peeler for the peeling of mother corms.
Study Design: CCRD (Central composite rotatable design) method of the response surface methodology (RSM) technique.
Place and Duration of Study: Department of Agricultural Processing and Food Engineering, College of Agricultural Engineering and Technology, Odisha University of Agriculture and Technology, Bhubaneswar, Odisha (India), between June 2021 and December 2021.
Methodology: For maximum yield with minimum loss, the process was conducted with three different variables such as rotating disc speed (350, 450 and 550 rpm), peeling duration (60, 120 and 180 sec) and batch load (1, 1.5 and 2 kg) for responses such as peeling efficiency (ηp), material loss (ML) and peeling effectiveness (PE).
Results: The results showed that peeling performance was influenced by variations in disc speed, peeling duration, and batch load of the peeling process. Rotating disc speed of 455 rpm, peeling duration of 115 sec and 1.35 kg of batch load were found to be the optimum condition for taro corm peeling. The corresponding peeling efficiency, peeling effectiveness and material loss were 92.64 %, 84.87 % and 8.21% respectively.
Conclusion: This study showed that the method can be successfully utilized in the commercial processing of mother corms.
Naloxone Accessibility Under the State Standing Order Across Mississippi
Authors: Gravlee Emily , Ramachandran Sujith , Cafer Anne , Holmes Erin , McGregor Jacob , Jordan Taylor , Rosenthal Meagen 
Published: July 2023

ImportanceNaloxone is a life-saving medication for individuals experiencing an opioid overdose. Naloxone standing orders aim to make naloxone more available by allowing patients improved access to this medication at community pharmacies; however, lawful availability does not mean that this life-saving intervention is accessible to patients.ObjectiveTo characterize naloxone availability and out-of-pocket cost under the state standing order in Mississippi.Design, Setting, and ParticipantsThis telephone-based, mystery-shopper census survey study included Mississippi community pharmacies open to the general public in Mississippi at the time of data collection. Community pharmacies were identified using the Hayes Directories April 2022 complete Mississippi pharmacy database. Data were collected from February to August 2022.ExposuresMississippi House bill 996, the Naloxone Standing Order Act, signed into law in 2017, allowing pharmacists to dispense naloxone under a physician state standing order at a patient’s request.Main Outcomes and MeasuresThe main outcomes were naloxone availability under Mississippi’s state standing order and the out-of-pocket cost of available formulations.ResultsThere were 591 open-door community pharmacies surveyed for this study, with a 100% response rate. The most common pharmacy type was independent (328 [55.50%]), followed by chain (147 [24.87%]) and grocery store (116 [19.63%]). When asked, “Do you have naloxone that I can pick up today?” 216 Mississippi pharmacies (36.55%) had naloxone available for purchase under the state standing order. Of the 591 pharmacies, 242 (40.95%) were unwilling to dispense naloxone under the state standing order. Among the 216 pharmacies with naloxone available, the median out-of-pocket cost for naloxone nasal spray (n = 202) across Mississippi was $100.00 (range, $38.11-$229.39; mean [SD], $105.58 [$35.42]) and the median out-of-pocket cost of naloxone injection (n = 14) was $37.70 (range, $17.00-$208.96; mean [SD], $66.62 [$69.27]).Conclusions and RelevanceIn this survey study of open-door Mississippi community pharmacies, availability of naloxone was limited despite standing order implementation. This finding has important implications for the effectiveness of the legislation in preventing opioid overdose deaths in this region. Further studies are needed to understand pharmacists’ unwillingness to dispense naloxone and the implications of lack of availability and unwillingness for further naloxone access interventions.
Assessing the accuracy of paired and random sampling for quantifying plant–plant interactions in natural communities
Authors: Michalet Richard , Losapio Gianalberto , Kikvidze Zaal , Brooker Rob W. , Butterfield Bradley J. , Callaway Ragan M. , Cavieres Lohengrin A. , Lortie Christopher J. , Pugnaire Francisco I. , Schöb Christian 
Published: July 2023

AbstractPlant interactions in extreme environments are often inferred from spatial associations and quantified by means of paired sampling. Yet, this method might be confounded by habitat‐sharing effects. Here, we address whether paired and random sampling methods provide similar results at varying levels of environmental heterogeneity. We quantified spatial associations with the two methods at three sites that encompass different micro‐environmental heterogeneity and stress levels: Mediterranean environments in Canary Islands, Spain, and Sardinia, Italy, and a cold alpine environment in Hokkaido, Japan. Then, we simulated plant communities with different levels of species micro‐habitat preferences, environmental heterogeneity, and stress levels. We found that differences in species associations between paired and random sampling were indistinguishable from zero in a homogeneous space. When simulating codispersion over a decreasing abundance gradient, both sampling methods correctly identified facilitation and distinguished it from codispersion. Yet, the pairwise method provided higher facilitation estimates than the random one. At each site, there were strong differences between beneficiary species in their spatial association with nurse species, and associations became more positive with increasing stress in Spain. Most importantly, there were no differences in results yielded by the two methods at any of the different stress levels at the Spanish and Japanese sites. At the Italian site, although micro‐environmental heterogeneity was low, we found weakly significant differences between methods that were unlikely due to habitat‐sharing effects. Thus, the paired sampling method can provide significant insights into net and long‐term effects of plant interactions in spatially conspicuous environments.
A radiomics model enables prediction venous sinus invasion in meningioma
Authors: Wang Limei , Cao Yuntai , Zhang Guojin , Sun Dandan , Zhou Wusheng , Li Wenyi , Zhou Junlin , Chen Kuntao , Zhang Jing 
Published: July 2023

AbstractObjectivePreoperative prediction of meningioma venous sinus invasion would facilitate the selection of surgical approaches and predicting the prognosis. To predict venous sinus invasion in meningiomas, we used radiomic signatures to construct a model based on preoperative contrast‐enhanced T1‐weighted (T1C) and T2‐weighted (T2) magnetic resonance imaging.MethodsIn total, 599 patients with pathologically confirmed meningioma were retrospectively enrolled. For each patient enrolled in this study, 1595 radiomic signatures were extracted from T1C and T2 image sequences. Pearson correlation analysis and recursive feature elimination were used to select the most relevant signatures extracted from different image sequences, and logistic regression algorithms were used to build a radiomic model for risk prediction of meningioma sinus invasion. Furthermore, a nomogram was built by incorporating clinical characteristics and radiomic signatures, and a decision curve analysis was used to evaluate the clinical utility of the nomogram.ResultsTwenty radiomic signatures that were significantly related to venous sinus invasion were screened from 3190 radiomic signatures. Venous sinus invasion was associated with tumor position, and the clinicoradiomic model that incorporated the above characteristics (20 radiomic signatures and tumor position) had the best discriminating ability. The areas under the curve for the training and validation cohorts were 0.857 (95% confidence interval [CI], 0.824–0.890) and 0.824 (95% CI, 0.752–0.8976), respectively.InterpretationThe clinicoradiomic model had good predictive performance for venous sinus invasion in meningioma, which can aid in devising surgical strategies and predicting prognosis.
Black Bioinks from Superstructured Carbonized Lignin Particles
Authors: Mattos Bruno D. , Jäntti Noora , Khakalo Sergei , Zhu Ya , Miettinen Arttu , Parkkonen Joni , Khakalo Alexey , Rojas Orlando J. , Ago Mariko 
Published: July 2023

AbstractA renewable source of carbon black is introduced by the processing of lignin from agro‐forestry residues. Lignin side streams are converted into spherical particles by direct aerosolization followed by carbonization. The obtained submicron black carbon is combined with cellulose nanofibers, which act as a binder and rheology modifier, resulting in a new type of colloidal bioink. The bioinks are tested in handwriting and direct ink writing. After consolidation, the black bioinks display total light reflectance (%R) at least three times lower than commercial black inks (reduction from 12 to 4%R). A loading of up to 20% of nanofibers positively affects the cohesion of the dried bioink (1 to 16 MPa), with no significant reduction in light reflectance. This is a result of the superstructuring of the ink components, which disrupts particle packing, intensifies colloidal interactions, introduces light absorption, and non‐reflective multiple scattering.
Monovalent Charge Compensation Enables Efficient Lanthanide‐Based Near‐Infrared Perovskite LEDs
Authors: Yu Yan‐Jun , Wang Hong‐Shuai , Pan Jia‐Lin , Li Sheng‐Nan , Shen Wan‐Shan , Cheng Shu‐Ning , Jin Lu‐Jie , Wang Ya‐Kun , Li You‐Yong , Liao Liang‐Sheng 
Published: July 2023

AbstractLanthanide ions (Yb3+ or Er3+) alloying of CsPb(Cl1‐xBrx)3 quantum dots (QDs) to emit approaching 1000 nm show promise in near‐infrared light‐emitting diodes (NIR‐LEDs). High Yb3+ alloying ratio increases the electroluminance efficiency of emission at 990 nm and enables high external quantum efficiency (EQE) of NIR‐LEDs, however, the high alloying ratio also results in inferior material stability and PLQY drop because of Yb3+‐induced nanocrystal precipitation. This study finds that the heavy alloying of Yb3+ ions causes lattice distortion and coherent energy reduction of Yb3+: CsPb(Cl1‐xBrx)3 QDs, induced by two Yb3+ ions replacing three Pb2+, which leads to the collapse of the octahedral structure in ambient conditions. It posits that spontaneous monovalent ion (Na+) alloying can address the trade‐off between material stability and emission intensity. The Na+ occupies the vacancy of Pb2+ ions, relaxing the distortion in the lattice and improving the phase stability of octahedral structure, and this optimized structure in turn allows a higher Yb3+ alloying ratio. Stability measurements show that the Na+/Yb3+ co‐alloyed films show ten‐fold higher material stability and 2.0‐fold emission efficiency related to controls. It reports that as a result Na+/Yb3+ co‐alloyed NIR‐LEDs have an EQE of 6.4% at 990 nm, which is among the highest perovskite NIR‐LEDs beyond 950 nm.
Eliminating Local Electrolyte Failure Induced by Asynchronous Reaction for High‐Loading and Long‐Lifespan All‐Solid‐State Batteries
Authors: An Hanwen , Liu Qingsong , Deng Biao , Wang Jian , Li Menglu , Li Xin , Lou Shuaifeng , Wang Jiajun 
Published: July 2023

AbstractThe design of practical cathodes with high areal capacity in polymer‐based all‐solid‐state batteries remains challenged by the absence of an effective guiding principle that prolongs battery life‐span. Unlike liquid batteries, the notorious interface incompatibility between cathodes and electrolytes limited the cycling life of the all‐solid‐state batteries. Herein, this study proposes a dynamically stable cathode design with a fully covered surface, effectively mitigating interface failure and enabling the cyclic time of batteries with a cathode loading of 12.7 mg cm‒2 over 10 000 h. This study unveils the importance of local state of charge in affecting the interfacial properties of particles through local oxidative‐stability of electrolytes on the interface. This study shows that the phenomena can be strongly influenced by the porosity of the cathode through the perspective of discreteness of ion transport. These insights and approach provide a broader promise for solid batteries for long lifetime.
Effect of Core Yarn on Linear Actuation of Electroactive Polymer Coated Yarn Actuators
Authors: Mehraeen Shayan , Asadi Milad , Martinez Jose G. , Persson Nils‐Krister , Stålhand Jonas , Jager Edwin W.H. 
Published: July 2023

AbstractSmart textiles combine the features of conventional textiles with promising properties of smart materials such as electromechanically active polymers, resulting in textile actuators. Textile actuators comprise of individual yarn actuators, so understanding their electro‐chemo‐mechanical behavior is of great importance. Herein, this study investigates the effect of inherent structural and mechanical properties of commercial yarns, that form the core of the yarn actuators, on the linear actuation of the conducting‐polymer‐based yarn actuators. Commercial yarns were coated with poly(3,4‐ethylenedioxythiophene)‐poly(styrenesulfonate) (PEDOT:PSS) to make them conductive. Then polypyrrole (PPy) that provides the electromechanical actuation is electropolymerized on the yarn surface under controlled conditions. The linear actuation of the yarn actuators is investigated in aqueous electrolyte under isotonic and isometric conditions. The yarn actuators generated an isotonic strain up to 0.99% and isometric force of 95 mN. The isometric strain achieved in this work is more than tenfold and threefold greater than the previously reported yarn actuators. The isometric actuation force shows an increase of nearly 11‐fold over our previous results. Finally, a qualitative mechanical model is introduced to describe the actuation behavior of yarn actuators. The strain and force created by the yarn actuators make them promising candidates for wearable actuator technologies.
Multipotent Human Neonatal Cardiac‐Derived Mesenchymal Stem Cells Modulate Ileitis In Vivo
Authors: Gunasekaran Muthukumar , Bury Matthew I. , Sharma Tiffany T. , Wang Larry W. , Fuller Natalie J. , Krishnan Swetha T. , Kaushal Sunjay , Sharma Arun K. 
Published: July 2023

AbstractTransmural skip lesions are pathognomonic for Crohn's disease (CD). Despite advances toward CD treatment, disease recurrence remains a problem. CD requires novel therapies to modulate localized intestinal inflammation and promote intestinal epithelium healing. Human neonatal cardiac‐derived mesenchymal stem cells (nMSCs) demonstrate immune cell modulation accompanied by improved cardiac function recovery in myocardial infarction models. In the established CD‐like ileitis SAMP mouse model, direct skip lesion injection of nMSCs prevents ileal skip lesion growth and significantly down‐regulates the pro‐inflammatory milieu. Significant reduction in the percentage of skip lesion CD68+ macrophages (M1 Mφ, pro‐inflammatory) accompanied by an increase of CD206+ macrophages (M2 Mφ, anti‐inflammatory/pro‐regenerative) is observed in skip lesions following nMSCs injection compared to non‐injected and placebo controls (p < 0.05). Skip lesion size is significantly reduced along with pro‐inflammatory cytokines IFN‐y and TNF‐α, with an increase in intestinal tissue anti‐inflammatory cytokine IL‐10 production. nMSCs are also retained within skip lesions 5 weeks post‐treatment. nMSC administration promotes wound remodeling by modulating inflammatory immune cells and by increasing small bowel gastrointestinal transit with concomitant decreased segment gross pathology score compared to placebo control. Data from this study demonstrate that direct injection of nMSCs into ileal skip lesions attenuates inflammation and improves intestinal physiology.
Synergized Tricomponent All‐Inorganics Solid Electrolyte for Highly Stable Solid‐State Li‐Ion Batteries
Authors: Xu Guixiang , Zhang Xin , Sun Shuyang , Zhou Yangfan , Liu Yongfeng , Yang Hangwang , Huang Zhenguo , Fang Fang , Sun Wenping , Hong Zijiang , Gao Mingxia , Pan Hongge 
Published: July 2023

AbstractGarnet‐type oxide Li6.4La3Zr1.4Ta0.6O12 (LLZTO) features superior ionic conductivity and good stability toward lithium (Li) metal, but requires high‐temperature sintering (≈1200 °C) that induces high fabrication cost, poor mechanical processability, and high interface resistance. Here, a novel high‐performance tricomponent composite solid electrolyte (CSE) comprising LLZTO−4LiBH4/xLi3BN2H8 is reported, which is prepared by ball milling the LLZTO−4LiBH4 mixture followed by hand milling with Li3BN2H8. Green pellets fabricated by heating the cold‐pressed CSE powders at 120 °C offer ultrafast room‐temperature ionic conductivity (≈1.73 × 10−3 S cm−1 at 30 °C) and ultrahigh Li‐ion transference number (≈0.9999), which enable the Li|Li symmetrical cells to cycle over 1600 h at 30 °C with only 30 mV of overpotential. Moreover, the Li|CSE|TiS2 full cells deliver 201 mAh g−1 of capacity with long cyclability. These outstanding performances are due to the low open porosity in the electrolyte pellets as well as the high intrinsic ionic conductivity and easy deformability of Li3BN2H8.
Genetically Engineered‐Cell‐Membrane Nanovesicles for Cancer Immunotherapy
Authors: Cheng Qinzhen , Kang Yong , Yao Bin , Dong Jinrui , Zhu Yalan , He Yiling , Ji Xiaoyuan 
Published: July 2023

AbstractThe advent of immunotherapy has marked a new era in cancer treatment, offering significant clinical benefits. Cell membrane as drug delivery materials has played a crucial role in enhancing cancer therapy because of their inherent biocompatibility and negligible immunogenicity. Different cell membranes are prepared into cell membrane nanovesicles (CMNs), but CMNs have limitations such as inefficient targeting ability, low efficacy, and unpredictable side effects. Genetic engineering has deepened the critical role of CMNs in cancer immunotherapy, enabling genetically engineered‐CMN (GCMN)‐based therapeutics. To date, CMNs that are surface modified by various functional proteins have been developed through genetic engineering. Herein, a brief overview of surface engineering strategies for CMNs and the features of various membrane sources is discussed, followed by a description of GCMN preparation methods. The application of GCMNs in cancer immunotherapy directed at different immune targets is addressed as are the challenges and prospects of GCMNs in clinical translation.
High‐efficiency thermally activated delayed fluorescence materials via a shamrock‐shaped design strategy to enable OLEDs with external quantum efficiency over 38%
Authors: Li Gaoyu , Pu Junrong , Yang Zhan , Deng Huangjun , Liu Yanyan , Mao Zhu , Zhao Juan , Su Shi‐Jian , Chi Zhenguo 
Published: July 2023

AbstractTo achieve highly‐efficient organic light‐emitting diodes (OLEDs), great efforts have been devoted into constructing thermally activated delayed fluorescence (TADF) with high horizontal dipole ratios (Θ//). Here, we proposed a design strategy by integrating a rigid electron‐accepting oxygen‐bridged boron core with triple electron‐donating groups, which exhibited a “shamrock‐shape”, namely BO‐3DMAC and BO‐3DPAC. Benefiting from the rigid and large‐planar skeletons brought by shamrock‐shaped design, BO‐3DMAC and BO‐3DPAC exhibit high Θ// of 84%/70% and 93%/94% in neat/doped films, respectively, and finally furnish excellent external quantum efficiencies (EQEs) of up to 28.3% and 38.7% in 20 wt% doped OLEDs with sky‐blue emission, as well as adequate EQEs of up to 21.0% and 16.7% in nondoped OLEDs. This work unveils a promising strategy to establish high‐Θ// TADF emitters by constructing large‐planar molecular structures using shamrock‐shaped design.