bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quercetin Ameliorates Neuropathic Pain after Brachial Plexus Avulsion
via Suppressing Oxidative Damage through Inhibition of PKC/MAPK/
NOX Pathway
Authors: Huang Yanfeng , Zhang Xie , Zou Yidan , Yuan Qiuju , Xian Yan-Fang , Lin Zhi-Xiu 
Published: August 2023

Background:
Brachial plexus avulsion (BPA) animally involves the separation of spinal
nerve roots themselves and the correlative spinal cord segment, leading to formidable neuropathic pain
of the upper limb.

Methods:
The right seventh cervical (C7) ventral and dorsal roots were avulsed to establish a neuropathic
pain model in rats. After operation, rats were treated with quercetin (QCN) by intragastric administration
for 1 week. The effects of QCN were evaluated using mechanical allodynia tests and biochemical
assay kits.

Results:
QCN treatment significantly attenuated the avulsion-provoked mechanical allodynia, elevated
the levels of catalase (CAT), superoxide dismutase (SOD) and glutathione peroxidase (GPx) and total
antioxidant capacity (TAC) in the C7 spinal dorsal horn. In addition, QCN administration inhibited the
activations of macrophages, microglia and astrocytes in the C6 dorsal root ganglion (DRG) and C6-8
spinal dorsal horn, as well as attenuated the release of purinergic 2X (P2X) receptors in C6 DRG. The
molecular mechanism underlying the above alterations was found to be related to the suppression of
the PKC/MAPK/NOX signal pathway. To further study the anti-oxidative effects of QCN, we applied
QCN on the H2O2-induced BV-2 cells in vitro, and the results attested that QCN significantly ameliorated
the H2O2-induced ROS production in BV-2 cells, inhibited the H2O2-induced activation of
PKC/MAPK/NOX pathway.

Conclusion:
Our study for the first time provided evidence that QCN was able to attenuate pain hypersensitivity
following the C7 spinal root avulsion in rats, and the molecular mechanisms involve the
reduction of both neuro-inflammatory infiltration and oxidative stress via suppression of P2X receptors
and inhibition of the activation of PKC/MAPK/NOX pathway. The results indicate that QCN is a
natural compound with great promise worthy of further development into a novel therapeutic method
for the treatment of BPA-induced neuropathic pain.
Clinical effect of Virechana Karma in Madhumeha W.S.R. to Diabetes Mellitus – A Case Study
Authors: Jyoti Kaushik  , Ajay Kumar  
Published: July 2023

Lifestyle behaviours like smoking, unhealthy diet, and physical inactivity result in the development of chronic diseases, specifically heart disease, stroke, diabetes, obesity, metabolic syndrome, chronic obstructive pulmonary disease, and some types of cancer. These diseases can result in loss of independence, years of disability, or death, and impose a considerable economic burden on health services. Diabetes Mellitus is one of them. It is the burning issues now a days. Many patients lost their lives because of this disease. It is counted among the five major diseases responsible for morbidity and mortality. Diabetes Mellitus is responsible for Ischemic Heart Disease, Chronic Kidney Disease and non traumatic amputation of limbs. It is even seen in practice that many patients suffer from various kinds of diabetic complications even their blood sugar is well under control So, great work is required to deal with Diabetes. Here in this study. A male patient of age 57 years suffering from Diabetes Mellitus type-2 since 6 months came to OPD for Ayurvedic treatment. Snehapana with Panchatikta Ghrita and Virechana with Ichabhedi rasa with Erand tail and Godugdha is given to patient. A significant result was observed after treatment.
Analisis Pemberdayaan Masyarakat: Studi Komparatif Gerakan Ayo Kita Peduli dan Pusat Kesejahteraan Sosial
Authors: Wijayanti Arini , Muhamad Iqbal  , Abdullah Mirna Nur Alia 
Published: July 2023

Poverty alleviation has become one of Indonesia's Sustainable Development Goals (SDGs) targets to be achieved by 2030, with poverty placed as a primary focus in national development. This study aims to compare the empowerment processes undertaken by “Gerakan Ayo Kita Peduli “ and “Pusat Kesejahteraan Sosial “ (Social Welfare Center, Puskesos) in Husein Sasatranegara, Bandung. The research employs a qualitative approach with a comparative model. The findings indicate that “Gerakan Ayo Kita Peduli “ is more effective in providing empowerment due to its targeting of priority groups such as the elderly, orphans, and micro, small, and medium-sized enterprise (UMKM) practitioners. The program also enhances community capacity through the establishment of “Tokopeduli. “ On the other hand, “Puskesos “ carries out planned activities through neighborhood deliberations (musyawarah kelurahan), but it has not effectively improved living standards due to limited human resources. Both initiatives can conduct evaluations and implement improvements to achieve more effective empowerment. “Gerakan Ayo Kita Peduli “ should strengthen the educational aspect, while “Puskesos “ should enhance collaboration and community involvement.
Abstrak
Pengentasan kemiskinan telah menjadi salah satu target Sustainable Development Goals (SDGs) yang diupayakan Indonesia untuk dicapai pada tahun 2030 dengan menempatkan kemiskinan sebagai perhatian utama dalam pembangunan nasional. Kajian ini bertujuan untuk membandingkan proses pemberdayaan yang dilakukan oleh Gerakan Ayo Kita Peduli dan Pusat Kesejahteraan Sosial (Puskesos) di Kelurahan Husein Sasatranegara, Bandung. Kajian ini menggunakan metode kualitatif dengan model komparatif. Kajian ini menunjukkan bahwa Gerakan Ayo Kita Peduli lebih optimal dalam memberikan pemberdayaan karena menyasar kelompok prioritas seperti lansia, yatim dhuafa, dan penggiat UMKM. Program ini juga meningkatkan kapasitas masyarakat dengan pembentukan Tokopeduli. Puskesos juga memiliki kegiatan terencana melalui musyawarah kelurahan, namun belum efektif meningkatkan taraf hidup karena keterbatasan sumber daya manusia. Keduanya dapat melakukan evaluasi dan perbaikan untuk mencapai pemberdayaan yang lebih efektif. Gerakan Ayo Kita Peduli perkuat aspek pendidikan, sementara Puskesos tingkatkan kolaborasi dan keterlibatan masyarakat.
ДИАЛЕКТИЧЕСКАЯ МОДЕЛЬ ВСЕЛЕННОЙ
Authors: Беляев Анатолий 
Published: August 2023

Аннотация
В работе рассмотрена теоретическая модель структуры и эволюции бесконечной Вселенной, основанная на постулатах диалектического материализма. С позиций философских категорий «объекты и множества» Вселенная может мыслиться как универсальное бесконечное множество, потенциально бесконечно возрастающих, и вечно расширяющихся в пространстве материальных множеств. Эволюция Вселенной отражает преимущественное и частично необратимое преобразование энергии движения материальных множеств в энергию структур.
Барионная материя может быть аналогом потенциально бесконечно возрастающих в пространстве и вечных во времени структурированных материальных множеств. Материальные множества в виде биологической и разумной форм существования Материи, в настоящее время представленные только на планете Земля, в масштабе Вселенной могут стать следующими в иерархической последовательности, бесконечно возрастающих в пространстве структурированных материальных множеств, и существовать вечно.
Теория Стационарной Самосогласованной Вселенной
Authors: Авшалумов Александр 
Published: August 2023

С момента создания ОТО и последующих работ в космологии, вопрос о кривизне пространства во Вселенной (w > 0, w < 0 или w = 0 ) - считается один из наиболее главных и дискутируемых по сей день. Это естественно, ведь от кривизны пространства зависит: расширяется Вселенная, сжимается или является статичной. Эти дискуссии, позволили автору выдвинуть парадоксальную идею: одновременного существования во Вселенной трех взаимосвязанных пространств-времен (положительной, отрицательной и нулевой кривизны) и, уже на этой основе, разработать теорию, в которой каждое пространство-время играет свою собственную роль и развивается в строгом соответствии, со своим знаком кривизны.
Трех пространственно-временная модель строения Вселенной, предлагаемая автором, позволяет решить многие фундаментальные проблемы современной космологии и теоретической физики, а также создает основу для построения единой физической теории.
Futile Quest for Perfection: Understanding the Aesthetics of Wabi-sabi through Girish Karnad’s Hayavadana
Authors: Seth Deepali , Singh Dr. Sonal 
Published: August 2023

The essence of a man's existence is fundamental to the pursuit of perfection. It is regulated by several psychological and philosophical principles that play an emphasis on the distinctive and particular experiences that one has. It is portrayed as some abstract concept of "human nature," a compendium of categorical imperatives or precepts that govern individuals and their approach to life. The disorderliness of a human's qualities, the incompleteness of their thinking, and their flaws are fundamental to who they are. In terms of human entropy, the state of disorder and uncertainty always exists in an individual, which helps them to stabilize and adapt themselves to changing circumstances both inside and outside of them. The quest for perfection is therefore pointless because it reflects an internal burden that is sewn into the fabric of tension, anxiety, panic, and mental collapse and, in the end, calls into question an individual's fundamental identity. This fruitless endeavour in seeking the best puts a person's control over their life and being into doubt. Human aspirations result in human desperation, according to Karnad's interpretation of Hayavadana. The narrative's characters travel a path from exquisite imagining to terrible reality here. Therefore, it is revealed that the search for perfection is meaningless since it draws attention to one's difficulties, sorrows, responses, and powerlessness, which makes one feel absurd in the end. With the help of this research article, an attempt has been made to comprehend the aesthetics of Wabi-sabi and delve deeper into its philosophy to understand the search for ‘beauty in imperfection’. Under the influence of this Japanese theory, it is evident that one must embrace human entropy and stabilise within their dimensions.
Methods and Methodology used to Teach English Language in Secondary Schools in Dr. B R Ambedkar Konaseema District, Andhra Pradesh
Authors: Raju Dr. T. Sharon , Kumari Kadiyam Sajaya 
Published: August 2023

Communication skills in English have become very essential in this Information and Communication Technology (ICT) revolution era. People who have effective communication skills in English have better opportunities to either receive or disseminate knowledge. Almost entire higher education is being offered only in English and to communicate with people in a highly diversified country like India is once again through English.
For most of the students studying in state run schools, the status of oral and written communication skills is poor. The teachers and the students including the educational administrators prefer communicating in their mother tongue than to communicate in English. Much of the time, communication in English is influenced by mother tongue or local dialect in every part of India. The development of communication skills among students can be effectively understood by the materials and methodology of learning and teaching English language, and it is keenly observed from the communication point of view.
Lower body weight and increasing age are significant risk factors for complications following bi-oblique proximal ulnar osteotomy in dogs
Authors: Danielski Alan , de Marcos Carpio Isabel , Danielski Camilla , Farrell Michael , Solano Miguel Angel 
Published: August 2023

Abstract

OBJECTIVE
To report and evaluate the risk factors for complications following bi-oblique proximal ulnar osteotomy (PUO) in dogs.

ANIMALS
82 client-owned dogs (93 limbs).

METHODS
Clinical records of dogs treated with bi-oblique PUO over a 5-year period were reviewed. Postoperative radiographs were analyzed, and osteotomy location and angles were recorded; follow-up radiographs were reviewed to assess the degree of osteotomy healing. Complications were classified as minor, major, and catastrophic. Logistic regression analysis was performed to investigate possible associations between the predictor variables and occurrence of complications.

RESULTS
82 dogs (93 limbs) were included. Postoperative complications were documented in 39 limbs (13 major and 26 minor). The most common major complication was osteotomy nonunion (8 limbs), while the most common minor complication was delayed union (21 limbs). Statistical analysis revealed that lower body weight (P = .01) and older age (P = .04) were significantly associated with the development of postoperative complications.

CLINICAL RELEVANCE
In this study, lighter and older dogs were more likely to develop complications following bi-oblique proximal ulnar osteotomy. We did not identify an association between osteotomy angle and location on complication rate. Careful patient selection is therefore required to reduce the incidence of postoperative complications after bi-oblique PUO.
Genetic diversity and structure of Magnolia mexicana (Magnoliacea): A threatened species in eastern Mexico
Authors: Gutiérrez-Lozano Marisol , Sánchez-González Arturo , Octavio-Aguilar Pablo , Galván-Hernández Dulce María , Vázquez-García José Antonio 
Published: August 2023

Abstract
This study analyzes the diversity and genetic structure of seven natural populations of Magnolia mexicana (Yoloxóchitl), an endangered and endemic species distributed in the Mexican Sierra Madre Oriental. The objective of the analysis is to generate basic information for the development of management and conservation programs for this species. The variation and genetic structure were estimated based on 12 SSR markers. The results indicate that the expected heterozygosity was 0.63±0.02 and the allelic richness was 1.21±0.05. The analysis of molecular variance (AMOVA) showed that variation between individuals explains 49 % of the total variation, and variation within individuals explains 36 %. The technical Neighbor joining and the ordination diagram of the canonical discriminant analysis show that the populations are made up of two genetic groups mostly. By contrast with the model Bayesian grouping (obtained with the STRUCTURE program) indicated the formation the six genetics groups. Recent bottleneck effects were observed in all localities, except in Duraznillo, El Cajón, and Zapotla. The relationship between genetic and geographic distances was not significant, which rules out a structure determined by isolation; the results suggest that the diversity and genetic structure of the species are affected by local factors such as habitat fragmentation, land use change, and excessive use of the flowers and fruits of M. mexicana by the inhabitants. Therefore, it is a priority to implement management and conservation programs to guarantee their survival.
Some Results on the Generalized Cayley Graph of Complete Graphs
Authors: Neamah Suad Abdulaali , Erfanian Ahmad 
Published: July 2023

. Suppose that is the Cayley graph whose vertices are all elements of and two vertices and are adjacent if and only if . In this paper,we introduce the generalized Cayley graph denoted by which is a graph with a vertex set consisting of all column matrices in which all components are in and two vertices and are adjacent if and only if , where is a column matrix that each entry is the inverse of the similar entry of and is matrix with all entries in , is the transpose of and and m . We aim to provide some basic properties of the new graph and determine the structure of when is a complete graph for every , and n, m .
On the G-quadratic and LG-quadratic of the Exterior Algebra and Associated Algebra
Authors: Jawad Ruaa Yousuf 
Published: July 2023

Given an exterior algebra over a finite dimension vector space v, and let , where is a graded ideal in . The relation between the algebra and regarding to -quadratic and - quadratic will be investigated. We show that the algebra is - quadratic if and only if is - quadratic. Furthermore, it has been shown that the algebra is - quadratic if and only if is - quadratic.
Pola Sebaran dan Rendemen Hasil Gliserolisis Enzimatis Campuran CPO (Crude Palm Oil) dan PKO (Palm Kernel Oil)
Authors: Khasbullah Fizzaria , Murhadi Murhadi , Kurniawati Nurleni , Undadraja Bigi , Rini Hartari Widia 
Published: August 2023

Pemanfaatan minyak dalam industri pangan dan non pangan semakin meningkat dengan semakin banyaknya temuan tentang proses sintesis oleokimia yang dapat diterapkan dalam skala industri. MAG dan DAG digunakan sebagai bagian dari produk lemak dan sering dikaitkan dengan pengemulsi lainnya. Sintesis MAG dapat dilakukan secara kimia dan enzimatis. Proses gliserolisis menggunakan enzim lipase sebagai biokatalis memerlukan energi yang relatif rendah serta menghasilkan produk dengan kualitas yang lebih baik. Penelitian ini menggunakan gliserolisis enzimatis dan akan diamati pola sebaran produk gliserolisis yang menggambarkan tingkat kesempurnaan reaksi. Pola sebaran yang menggambarkan kesempurnaan reaksi adalah pola sebaran yang memiliki spot yang menyebar secara teratur (tidak acak/lurus).
Percobaan dilakukan dengan faktor tunggal dan dua ulangan. Data disajikan dalam bentuk tabel dan histogram, kemudian hasilnya dibahas secara deskriptif. Faktor perlakuan, yaitu perbandingan campuran CPO dan PKO yang terdiri dari 11 perbandingan CPO dan PKO : 0,2; 0,4; 0,6; 0,8; 1,0; 1,2; 1,4; 1,6; 1,8 dan dua kontrol. Perbandingan 0,2 berbanding 0,8 merupakan campuran CPO dan PKO, dimana fraksi CPO lebih kecil dibandingkan fraksi PKO, perbandingan 1,0 fraksi CPO sama dengan CPO, dan perbandingan 1,2 berbanding 1,8 adalah campuran CPO dan PKO lebih besar dimana fraksi CPO lebih tinggi dari PKO.
Berdasarkan pengamatan yang dilakukan, gliserolisis campuran CPO dan PKO dalam berbagai nisbah, menghasilkan pola sebaran pada lempeng KLT yang beraturan dan nilai Rf (Retardation factor) menunjukkan dari yang terdekat hingga terjauh adalah MAG, DAG, ALB, dan TAG dengan Rf berturut-turut 0,01;0,12;0,31;0,57. Rendemen MAG tertinggi dihasilkan oleh hasil gliserolisis kontrol CPO (83,90%) diikuti oleh kontrol PKO (74,90%) dan campuran CPO-PKO nisbah 0,8 (73,71%). Rendemen MAG-DAG tertinggi dihasilkan oleh campuran CPO-PKO nisbah 1,6 (93,21%) diikuti oleh control CPO (91,88%) dan nisbah 0,8 (73,71%).
Alfisol Soil Fertility Before Planting and After Harvest as Meloon Planting Media with Bioboost Fertilization
Authors: Fajeriana Nurul , Abdul Gafur Muzna Ardin 
Published: August 2023

Soil fertility is important in the cultivation process. Soil fertility is the potential of the soil to provide nutrients in sufficient quantities in available and balanced forms to ensure optimum plant growth and production. The current availability of nutrients in the soil has decreased as a result of continuous land use with the use of chemical fertilizers in the cultivation process, plus leaching and erosion by rainwater, not least in Alfisol soils. Therefore, fertilization with organic materials is carried out, namely the provision of Bioboost fertilizer. Bio boost is a biological fertilizer containing superior soil microorganisms, useful for increasing soil fertility as a result of soil biochemical processes. One of the applications of organic cultivation is the cultivation of melon (Cucumis melo L.) because melon is a plant that has high economic value and is profitable to be cultivated as a source of income for farmers. Based on this, a study was conducted to determine the nutrient status of Alfisol soil before planting and after harvesting which was used as a Melon plant with various concentrations of Bioobost fertilization. Furthermore, for the analysis of soil fertility, laboratory analysis was carried out by taking 1 kg of disturbed soil samples that had been air-dried and then analyzing soil properties, namely texture, pH (H2O), C-Organic (%), Nitrogen (%), P2O5 (ppm), K (cmol kg-1), Ca (cmol kg-1), Mg (cmol kg-1), Na (cmol kg-1), Na (cmol kg-1), CEC (cmol kg-1), and KB (%). The application of Bio boosts fertilizer showed an increase in the nutrient status of Alfisol soil as a Melon growing from low to moderate categories before planting to medium to high categories after harvest. The more concentration of Bioboost fertilizer given, the soil nutrient status also increases. The concentration of P4 (1100ml bio boost + 400ml water) gave the highest increase in nutrient status.
Keywords: bioboost; soil-fertility; melon
The Role of Customer Satisfaction in Improving the Performance of Sail (Steel Authority of India LTD)
Authors: Baa Roshan , Chattoraj A K 
Published: August 2023

Purpose: The study focussed on the influence of customer satisfaction on reform policies and the performance of SAIL and attempts to investigate the influence of reform policies in improving the performance of SAIL (De, 2014).

Theoretical Framework: Research examined the moderating role of customer satisfaction between reform policies and the performance of SAIL. A conceptual model with two hypotheses was developed and data were collected from 385 employees and managerial staff in the form of a questionnaire from five integrated units of SAIL (Jain et al., 2014).

Design/Methodology/Approach: Paper goes through the quantitative and qualitative discussion to analyse the performance of SAIL against the backdrop of liberalization measures introduced in the 1990s and afterward. The study will analyse two different periods of SAIL: Before 1990 and after 1990.

Findings: The findings of the study provide useful insights to evaluate and improve SAIL's reform policies and performance and to enhance customer satisfaction.

Conclusion: Article paves the way to huge scope for future researchers. The scope of the study can be further broadened by including several PSEs across multiple industries to gain comprehensive findings about the impact of reforms on the performance of different types of PSEs.
ATAS NOTARIAIS COMO INSTRUMENTOS DE PROVA NA DESJUDICIALIZAÇÃO DOS CONFLITOS
Authors: Cervi Katyane , Rodrigues Leonel Cezar , Bonotto Barbosa Ricardo Augusto 
Published: August 2023

Este estudo tem como objetivo analisar a efetividade da utilização das atas notariais como instrumentos de prova na desjudicialização de conflitos e como garantir a produção adequada desses documentos. A pesquisa aborda a importância dos direitos humanos fundamentais e sua positivação nas Declarações de Direitos, bem como o direito à honra, integridade moral e nome, todos relacionados à pessoa e sua proteção diante do princípio da dignidade da pessoa humana. A ata notarial é apresentada como meio de prova à garantia dos direitos fundamentais da honra e integridade da pessoa, dotada de fé pública e eficácia probatória na presunção veracidade dos fatos jurídicos narrados. A metodologia adotada é a revisão bibliográfica exploratória, pautada em fontes documentais, legislações e Código de Normas Extrajudiciais. Observou-se as inovações implementadas pelas legislações, as quais trouxeram maior amplitude nos direitos relacionados à pessoa e a proteção desses direitos, principalmente na área extrajudicial. Conclui-se que a ata notarial é um instrumento de prova e garantia para resguardar os direitos fundamentais quando lesionados, desde que produzida de forma adequada e regulamentada pelo Estado.