bluuebunny/crossref_metadata_2025_split huggingface dataset:
Abductor muscle function after anterolateral approach in patients with unilateral end-stage hip osteoarthritis undergoing total hip arthroplasty: A prospective study
Authors: Wongsak Siwadol , Jarungvittayakon Chavarat , Chulsomlee Kulapat , Jaovisidha Suphaneewan , Sa-ngasoongsong Paphon 
Published: March 2023

BackgroundTotal hip arthroplasty (THA) is a successful procedure for treating end-stage hip osteoarthritis (OA). Regarding the surgical approach for THA, the anterolateral (AL) approach, which requires anterior hemimyotomy of the gluteus medius muscle, has shown a long-term favorable outcome. However, to date, complete information related to hip abductor muscle outcomes after the AL approach is unavailable. This study therefore aimed to evaluate the postoperative outcome of patients who undergo THA using the AL approach in terms of hip abductor muscle recovery, pain, function, and muscle healing status.MethodsTwenty patients diagnosed with unilateral end-stage hip OA underwent cementless THA with the AL approach. All patient procedures were performed by a single surgeon. Preoperative and postoperative data were collected at 2-week, 6-week, 3-month, and 6-month follow-up periods. Hip abductor muscle power was measured via handheld dynamometer. The healing of the musculotendinous repair was evaluated with magnetic resonance imaging at 9 months.ResultsAfter THA, hip abductor muscle power in the operated hip significantly increased as early as 3 months post-procedure when compared with the preoperative value (p &lt; 0.05). The other parameters—including pain score, Harris hip score, and WOMAC score—significantly improved as early as 2 weeks post-operation (p &lt; 0.05). In all patients, MRI scans showed good healing of the muscle repair site without a gap in the gluteus medius muscle. However, three patients (15%) had some fibrosis and tendon swelling at the repair site.ConclusionThis study demonstrated that patients with end-stage hip OA could experience significantly improved hip abductor motor function as early as 3 months after undergoing THA with the AL approach. Moreover, despite patients experiencing anterior hemimyotomy of the gluteus medius muscle, no significant complications emerged at the muscle repair site in the AL approach.
Secondary Metabolites with Antifungal Activities from Mangrove Derived Fungus Monascus purpureus WMD2424
Authors: Wu Ming-Der , Chen Jih-Jung , Cheng Ming-Jen 
Published: March 2023

The mold Monascus, also called red yeast rice, anka, or koji, has been used as the natural food coloring agent and food additives for more than 1000 years in Asian countries. It has also been used in Chinese herbology and traditional Chinese medicine due to its easing digestion and antiseptic effects. However, under different culture conditions, the ingredients in Monascus-fermented products may be changed. Therefore, an in-depth understanding of the ingredients, as well as the bioactivities of Monascus-derived natural products, is important. Here, through the thorough investigation into the chemical constituents of M. purpureus wmd2424, five previously undescribed compounds, monascuspurins A–E (1–5), were isolated from the EtOAc extract of mangrove-derived fungus Monascus purpureus wmd2424 cultured in RGY medium. All the constituents were confirmed via HRESIMS and 1D- and 2D-NMR spectroscopy. Their antifungal activity was also evaluated. Our results showed that four constituents (compounds 3–5) possessed mild antifungal activity against Aspergillus niger, Penicillium italicum, Candida albicans, and Saccharomyces cerevisiae. It is worth mentioning that the chemical composition of the type strain Monascus purpureus wmd2424 has never been studied.
STUDENTS-PSYCHOLOGIST’S SELF-ACTUALIZATION INDICATORS EMPIRICAL RESEARCH
Authors: Lavrinenko V. 
Published: March 2023

The article analyzes the results of the theoretical and empirical study of students-psychologist’s self-actualization indicators. A generalized theoretical analysis of the individual self-actualization phenomenon, its components and the connection with the professional formation process of a psychologist-specialist is presented.
The results of an empirical study of students-psychologist’s self-actualization indicators in the context of their professional formation are analyzed. It is summarized that future specialists are characterized by medium indicators of self-actualization and personality maturity, with sufficiently increased orientations of future specialists towards manifestations of contact, perception of their own Self, a valuable component of self-actualization and orientation towards a humanistic perception of human nature, orientation towards knowledge. It has been found that students-psychologists are characterized by a predominance of achievement motivation, attitude towards their own Self, and the ability to be in contact with communication partners. Identified trends are analyzed in the context of compliance with the requirements for the professional activity of a psychologist.
The Formation of Clinical Transfusiologyin Belarus (to the 100th Anniversary of the First Blood Transfusion in Domestic Medicine)
Authors: Гольдинберг Б.М. , Климович О.В. , Секретова Е.Б. 
Published: March 2023

Цель исследования. Провести анализ значимости этапа становления белорусской трансфузиологии и показать вклад ученых и практикующих врачей в этот процесс. Материалы и методы. Изучены архивные и музейные документы, а также литературные источники по теме организации и становления производственной и клинической трансфузиологии в Беларуси в период с 1923 по 1941 год. Результаты и обсуждение. Проведен обзор архивных и литературных источников об истории научного обоснования переливания крови и особенностях его становления в Беларуси. Этому процессу способствовало участие ученых и опытных практикующих врачей. Выводы. Становление клинической трансфузиологии в Беларуси прошло три этапа: единичных переливаний крови (1923–1931), регулярных трансфузий (1932–1937) и массовых переливаний крови (1938–1941).
Purpose. To analyze the significance of the stage of formation of Belarusian transfusiology and to show the contribution of scientists and practitioners in this process. Materials and methods. Archival and museum documents, as well as literary sources of research on the organization and formation of industrial and clinical transfusiology in Belarus in the period from 1923 to 1941 were studied. Results and discussion. The review of archival and literary sources of the history of the scientific justification of blood transfusion and the peculiarities of its formation in Belarus was carried out. This process was facilitated by the participation of scientists and experienced practitioners. Conclusions. The formation of clinical transfusiologyin Belarus went through three stages: single blood transfusions (1923–1931), regular transfusions (1932–1937) and mass blood transfusions (1938–1941).
Combined Deficiencies of Blood Clotting Factors: Advantages of Modern Therapy
Authors: Кожанова И.Н. , Романова И.С. , Чак Т.А. 
Published: March 2023

При значительных дефицитах факторов свертывания у пациентов отмечаются жизнеугрожающие кровотечения. Основой лечения пациентов с комбинированными дефицитами факторов свертывания крови является специфическая заместительная терапия лекарственными препаратами или компонентами крови, содержащими дефицитные (сниженное количество или отсутствие) факторы свертывания. Заместительная терапия исторически проводится с использованием свежезамороженной плазмы, относящейся к компонентам крови, в то время как использование препарата ОктапласЛГ по сравнению со свежезамороженной плазмой ассоциируется с высоким уровнем эффективности и безопасности. ОктапласЛГ, относящийся к лекарственным препаратам, производится по правилам надлежащей производствен- ной практики (GMP). Этот препарат прошел полный спектр доклинических и клинических испытаний в соответствии с правилами надлежащей клинической практики (GCP). Лекарственный препарат характеризуется высоким уровнем инфекционнойбезопасности, минимальным риском развития осложнений, стандартизированным содержанием активных компонентов, что снижает общий объем трансфузий.
Life-threatening bleeding is noted in patients with significant deficits of coagulation factors. The basis for the treatment of patients with combined deficiencies of blood clotting factors is specific replacement therapy with drugs or blood components containing deficient (reduced or absent) clotting factors. Replacement therapy is traditionally performed using freshly frozen plasma related to blood components. The use of OctaplasLG compared with freshly frozen plasma is associated with a high level of efficiency and safety. ОctaplasLG is medicinal product manufactured according to the rules of good manufacturing practice (GMP) and subjected to a full range of preclinical and clinical trials in accordance with the rules of good clinical practice (GCP). The medicine is characterized by high level of viral safety, minimal risk of complications.
Genetic Diversity of Potential Hematopoietic Stem Cell Donors of Russian and Belarusian Registers
Authors: Бубнова Л.Н. , Глаз Е.В. , Кузьмич Е.В. , Павлова И.Е. , Искров И.А. , Сидоркевич С.В. , Старцева И.Ю. , Усс А.Л. 
Published: March 2023

Трансплантация гемопоэтических стволовых клеток крови широко используется для лечения онкогематологическихзаболеваний и некоторых состояний, связанных с дефицитом кроветворения и иммуногенеза. Эффективный донорский поиск является одной из важнейших составляющих успеха трансплантации. Совпадение пар «донор – реципиент» по 10/10 HLA-аллелям (гены HLA-A, -B, -C, -DRB1 и -DQB1) – «золотой стандарт» успешного поиска совместимого донора для проведения аллогенной неродственной трансплантации стволовых клеток. Регистры играют ключевую роль в организации взаимодействия между врачами трансплантационного центра и специалистами, контактирующими с донором. Международное сотрудничество регистров доноров костного мозга способствует повышению эффективности поиска доноров для пациентов, нуждающихся в проведении аллогенной трансплантации гемопоэтических стволовых клеток. В статье представлены результаты сравнительного анализа иммуногенетических характеристик потенциальных доноров гемопоэтических стволовых клеток крови и костного мозга регистра ФГБУ РосНИИГТ ФМБА России и регистра Республики Беларусь. Показаны общие закономерности и характерные особенности профиля групп HLA-аллелей и HLA-гаплотипов в сравниваемых регистрах.
Hematopoietic blood stem cell transplantation is widely used for the treatment of hematological malignancies and some conditions associated with deficiency of hematopoiesis and immunogenesis. An effective donor search is one of the essential components of the success of transplantation. Matching donor-recipient pairs by 10/10 HLA alleles (HLA-A, -B, -C, -DRB1 and -DQB1 genes) is the gold standard for successful search for a compatible donor for allogeneic unrelated stem cell transplantation. The registries play a key role in organizing the interaction between the doctors of the transplant center and the specialists in contact with the donor. International cooperation of bone marrow donor registries contributes to improving the efficiency of donor search for patients requiring allogeneic hematopoietic stem cell transplantation. The article presents the results of a comparative analysis of the immunogenetic characteristics of potential hematopoietic stem cell donors in the Register of the FSBI RosNIIHT FMBA of Russia and the Register of the Republic of Belarus, demonstrates the general patterns and features of the profile of HLA-alleles groups and HLA-haplotypes in the compared registers.
Refractoriness to Platelet Transfusions: Diagnosis and Selection of Donor-Recipient Pairs
Authors: Дашкевич Э.В. , Бухвальд Н.А. , Пешняк Ж.В. , Семенов Г.В. , Карпенко Ф.Н. 
Published: March 2023

В статье на основании клинического материала изучена частота встречаемости анти- тел к антигенам тромбоцитов HLA и HPA у пациентов с рефрактерностью к трансфузиям тромбоцитов различных нозологических групп. Проведен подбор тромбоцитных компонентов крови в соответствии с выявленной аллосенсибилизацией, оценена клинико-лабораторная эффективность через 24 часа.
In the article, on the basis of clinical material, the frequency of occurrence of antibodies to platelet antigens HLA and HPA in patients with refractoriness to platelet transfusions of various nosological groups was studied. The selection of platelet blood components was carried out in accordance with the identified allosensitization, the clinical and laboratory efficacy was evaluated after 24.
LONGTERM FORECAST OF BIOLOGICAL DEVELOPMENT OF PHYTOPHAGES ON BLACK CURRANT
Authors: Bakalova A. 
Published: March 2023

The article presents the results of scientific research on the biological development of the large currant aphid, the red currant head aphid and the gooseberry shoot aphid in the currant agrocenosis. Based on the analysis of the multi-year dynamics of the development of phytophages, a phenological calendar was built, which clearly shows the period of manifestation of the greatest harmfulness of these pests, which is indicated in the third decade of April, while according to the phenological phase of development, this is the VI stage of the biological development of currants. Aphids overwinter in the egg stage at the base of the currant bud. The embryonic development of the egg ends at the beginning of the plant's sap flow. The metamorphosis of this species refers to an incomplete transformation, and therefore parthenogenesis was observed during the experiment. At the 4th stage of organogenesis, we observed the emergence of larvae of the founders, light green in color and spiky sucking mouthparts, which after 2-3 days begin active feeding, which was evidenced by damaged leaves that changed their color over time. The color of leaves damaged by redcurrant aphid has a clear transition from light yellow to red with a halo-shaped bulge. In this species, the salivary enzyme enhances the growth and development of cells, while in the gooseberry shoot aphid, on the contrary, cells die and at the same time cause cell death.
According to our observations, it has been proven that the development of these phytophages falls on the stage of organogenesis of currant blossoms, and it is strictly forbidden to carry out any plant protection measures during this period. And therefore, we conducted a long-term study of both black currant and sucking phytophages. Such a significant plant-phytophagous combination makes it possible to carry out preventive actions early in the spring on the biological development of sucking phytophages, where in recent years their harmfulness occupies one of the main places, while parthenogenetic females cause significant damage, reducing the yield and quality of berries due to disruption of the normal flow physiological processes of photosynthesis. As a result of nutrition of a parthenogenetic individual, the shoots lag behind in growth, have clearly expressed curvatures of various shapes. It is possible to reduce the colonization of black currant by sucking phytophages by implementing phenological forecasting.
GREENHOUSE GAS EMISSIONS FROM AGRICULTURAL ACTIVITIES AND THEIR DYNAMICS DURING 1990-2020
Authors: Tymoshchuk O. , Tymoshchuk O. , Matviychuk B. 
Published: March 2023

Ukraine, as a Party of the UN FCCC, cooperates with international organizations in the field of environmental protection, including ensuring the fulfillment of obligations in the field of climate change, namely to reach the level of greenhouse gas emissions in 2030 in the amount of exceeded 60% of the level of 1990. The agricultural sector has a significant contribution to the total emissions of greenhouse gases in Ukraine, which during 1990-2020 fluctuated between 9-14%. In agriculture, the emissions of three greenhouse gases (methane, nitrous oxide and carbon dioxide) are considered, the emissions of which lead to activity in two branches – livestock and plant growing.
Livestock is characterized by such processes as enteric fermentation and manure management, which are accompanied by the emission of mainly methane. The key factors that determine the dynamics of greenhouse gas emissions in livestock are the number of agricultural animals and the type of manure management system, which is used to collect, transport, store and use manure. The largest contribution in terms of greenhouse gas emissions is made by the category of enteric fermentation (mainly enteric fermentation of cattle), the share of which during the 1990- 2020 fluctuated mainly in the range of 80-85%, and as of 2020 it decreased to 79.3%.
The amount of emissions in plant growing is determined by factors specific to each process, namely: the amount of fertilizers (nitrogen and organic) applied to agricultural soils, the amount of applied liming materials, the amount of N in crop residues, the area of organic soils for crop planting etc. The main greenhouse gas in this area is nitrous oxide, the dynamics of whose emission is generally characterized by two directions – a significant and rapid reduction by more than 60% by 2003 and subsequent gradual growth. The development of different areas of plant growing takes place in different directions and with different intensity, and therefore have different contributions to the total volume of N2O emissions. The largest share of emissions, both in 1990 and in 2020, comes from N application with mineral fertilizers and N application with crop residues.
SYNTHESIS OF POTENTIAL LIQUID CRYSTALS WITH CHOLESTEROL FRAGMENT BY WITTIG REACTION
Authors: Lystvan V. , Zhmurchuk A. , Lystvan V. 
Published: March 2023

Liquid crystals are substances that owing to the features of their structure and physical properties are of interest not only as objects for theoretical research, but also significantly important practically due to the possibilities of their effective application in various brunches of industry, medicine, in household etc. Among the known classes of liquid crystals, substances known as cholesterics are an important group.
Cholesteric liquid crystals demonstrate very high optical activity, that significantly exceeds the optical activity of most other known classes of organic compounds. Their ability for appreciable change of color at change of the temperature and environment composition is also practically important.
Among all compounds belonging to the class of cholesterics an important place possess cholesterol derivatives, especially cholesterol esters. Therefore, the elaboration of new methods of their synthesis and the introduction of new functional groups into their molecules are an urgent tasks indeed.
This work is devoted to the investigation of the possibility of synthesis of new cholesterol derivatives, namely cholesteryl esters of unsaturated acids by the Wittig reaction - the interaction of various classes of aldehydes with phosphonium salts, with the intermediate formation of phosphorus ylides - alkylidene phosphoranes. We found that the Wittig reaction is a convenient method for the synthesis of cholesteryl esters of unsaturated carboxylic acids. We have developed methods for the synthesis of potential cholesteric liquid crystals by the Wittig reaction, which use a phosphonium salt containing a cholesterol fragment and corresponding aldehydes. The process proceed without the release of an intermediate compound – alkylidene phosphorane, which reduces the labor intensity of the method.
The application of various aldehydes enables the easily obtaining of cholesteryl esters of unsaturated acids containing various aliphatic, aromatic and heterocyclic fragments in the acid radical. The reaction takes place in mild conditions, without using of high temperatures or aggressive environments. The resulting esters show signs of mesophase formation, which is a confirmation of their liquid crystalline properties.
Management of fisheries and restoration of whitefish-nelmushka commercial stocks in Kubenskoye Lake of Vologda Region
Authors: Konovalov A. F. , Borisov M. Ya. , Tropin N. Yu. , Ignashev A. A. , Neporotovskii S. A. 
Published: March 2023

The purpose of this article is analysis of the relevance of whitefish commercial fisheries regulation in Kubenskoye Lake and development of measures to preserve the endemic whitefish population, increase its commercial stocks and catches.The material for the study is the statistics of whitefish-nelmushka catches in Kubenskoye Lake and the longterm dynamics of the size and age characteristics, terms of puberty.The research methods: field ichthyological materials were collected and processed according to standard methods; the fishing stocks were estimated based on the results of the analysis of non-water fishing catches, as well as taking into account the volume of water filtered by fixed fishing nets per unit of time.Results: the long-term dynamics of whitefish-nelmushka catches are described in the article. The effectiveness of its fisheries regulation has been studied. Fishing does not have a significant impact on the whitefish abundance dynamics. The exclusion of whitefish from the category of aquatic biological resources, in respect of which the total allowable catch is established, is justified in the article. The size and age population characteristics of the whitefish, age of puberty last years have been summarized in the article.Practical significance: artificial reproduction of the Kubenskoye Lake whitefish is recommended to be carried out to restore the population abundance, which is significant for the preservation of the gene pool of the polymorphic species Coregonus lavaretus. Recommendations on changing the Fishing Rules for the Northern Fishery Basin to reduce the legal size for whitefish-nelmushka were developed for the implementation of commercial and recreation fisheries.
Investigating the Effective Technique Used by Secondary School Students in Strengthening Reading Comprehension
Authors: Ishag Elhady Ishag Hmouda , Ahmed Sabir Mirgani Ali , Abdalhaliem Abdalla  Elfadil Mohammed , Mohammed-Noor Tohami Mohammed Hassan 
Published: March 2023

This study aims at investigating the effective technique used by secondary school students in strengthening reading comprehension. The study adopted the experimental method. Pre-posttest test is used as a primary tool for data collection. The population of the study is year students of English- College of Education at SUST. The sample of study drawn from the population consisted of 44 students who were selected randomly. This study used the statistical package for social science (SPSS) program to analyze and verify the hypotheses. The results showed that pre-test and posttest show that there are statistical significance differences among the respondents of experimental group in terms of reading technique. On the other hand, students unable to use scanning techniques while practicing reading in the classroom. Furthermore, students do not use skimming technique for obtaining general information. The study recommended that students should be aware about different types of reading skill. Teachers should consider students' level when using reading techniques.
Caracterización de la salud mental de estudiantes universitarios de enfermería
Authors: Simental-Chávez Lorena 
Published: March 2023

La presente investigación tiene como objetivo conocer las características del estado de la salud mental en estudiantes universitarios de la licenciatura en enfermería de la Universidad Autónoma de Baja California, campus Mexicali. Para la recolección de datos se utilizó el Cuestionario de Salud General de Golberg y los resultados se analizaron con el programa estadístico para las ciencias sociales SPSS 22, fue aplicado a 204 estudiantes, de los cuales 70.1% fueron del sexo femenino y 29.9% del sexo masculino, el 36.3% se encuentran cursando el tercer semestre de la licenciatura en Enfermería, mientras que el 33.3% son de cuarto semestre y un 30.4% de quinto semestre. El 62.3% de los estudiantes oscilan entre los 20 – 21 años de edad. Una vez analizadas las subescalas del cuestionario de salud general de Golberg, se observa que el porcentaje de casos detectados con problemas de salud mental es bajo.