bluuebunny/crossref_metadata_2025_split huggingface dataset:
Spatial regulation of plant hormone action
Authors: Wong Cynthia , Alabadí David , Blázquez Miguel A 
Published: July 2023

Abstract
Although many plant cell types are capable of producing hormones, and plant hormones can in most cases act in the same cells in which they are produced, they also act as signaling molecules that coordinate physiological responses between different parts of the plant, indicating that their action is subject to spatial regulation. Numerous publications have reported that all levels of plant hormonal pathways, namely metabolism, transport, and perception/signal transduction, can help determine the spatial ranges of hormone action. For example, polar auxin transport or localized auxin biosynthesis contribute to creating a differential hormone accumulation across tissues that is instrumental for specific growth and developmental responses. On the other hand, tissue specificity of cytokinin actions has been proposed to be regulated by mechanisms operating at the signaling stages. Here, we review and discuss current knowledge about the contribution of the three levels mentioned above in providing spatial specificity to plant hormone action. We also explore how new technological developments, such as plant hormone sensors based on FRET (fluorescence resonance energy transfer) or single-cell RNA-seq, can provide an unprecedented level of resolution in defining the spatial domains of plant hormone action and its dynamics.
Advances in cis-element- and natural variation-mediated transcriptional regulation and applications in gene editing of major crops
Authors: Cui Yue , Cao Qiao , Li Yongpeng , He Mingqi , Liu Xigang 
Published: July 2023

Abstract
Transcriptional regulation is crucial to control of gene expression. Both spatio-temporal expression patterns and expression levels of genes are determined by the interaction between cis-acting elements and trans-acting factors. Numerous studies have focused on the trans-acting factors that mediate transcriptional regulatory networks. However, cis-acting elements, such as enhancers, silencers, transposons, and natural variations in the genome, are also vital for gene expression regulation and could be utilized by clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9)-mediated gene editing to improve crop quality and yield. In this review, we discuss current understanding of cis-element-mediated transcriptional regulation in major crops, including rice (Oryza sativa), wheat (Triticum aestivum), and maize (Zea mays), as well as the latest advancements in gene editing techniques and their applications in crops to highlight prospective strategies for crop breeding.
Control ofListeria monocytogenesin a fresh cheese using aromatic and medicinal plants and enterocin: a comparative study
Authors: Ananou Samir , Bouraqqadi Meryem , Zouhri Nada , El Kinany Said , Manni Laila 
Published: July 2023

AbstractThe aim of this study was to investigate the effectiveness of essential oils (EOs) or crude extracts (CEs) of eight aromatic and medicinal plants (AMPs) and its association with enterocin OS1 on Listeria monocytogenes and food spoilage bacteria in Moroccan fresh cheese. The cheese batches were treated with EO of Rosmarinus officinalis, Thymus vulgaris, Syzygium aromaticum, Laurus nobilis, Allium sativum, Eucalyptus globulus, or CE of Crocus sativus and Carthamus tinctorius, and/or enterocin OS1, and stored for 15 days at 8°C. The data were subjected to correlations analysis, variance analysis, and principal components analysis. Results clearly showed a positive correlation between L. monocytogenes reduction and storage time. Moreover, reduction on Listeria counts induced by Allium-EO and Eucalyptus-EO reached 2.68 and 1.93 Log CFU/g with respect to untreated samples after 15 days, respectively. Similarly, enterocin OS1 alone has significantly reduced the L. monocytogenes population with 1.46 Log CFU/g. The most promising result was the synergy observed between many AMPs and enterocin. Indeed, treatments with Eucalyptus-EO + OS1 and Crocus-CE + OS1 decreased the Listeria population to undetectable after only 2 days and throughout the storage period. These findings suggest a promising application/use of this natural combination, which preserves the safety and long-lasting conservation of fresh cheese.
The X-ray point source population hosted by globular clusters in the elliptical galaxy NGC 4261
Authors: Nair Sneha , Dage Kristen C , Haggard Daryl , Kundu Arunav , Plotkin Richard M , Rhode Katherine L , Zepf Stephen E 
Published: July 2023

ABSTRACT
Utilizing archival Chandra X-ray Observatory data and Hubble Space Telescope globular cluster catalogues, we probe the time-domain properties of the low mass X-ray binary population in the elliptical galaxy NGC 4261. Of the 98 unique X-ray sources identified in this study, 62 sources are within the optical field of view and, of those, 33 per cent are aligned with an optical cluster counterpart. We find twenty X-ray sources coincident with globular clusters; two are previously discovered ultra-luminous X-ray sources (ULXs) and eighteen are low mass X-ray binaries (GCLMXBs) with LX &lt; 1039 erg s−1. ULXs are a heterogeneous class of extremely bright X-ray binaries (LX &gt; 1039 erg s−1) and ULXs located in globular clusters (GCULXs) and may be indicators of black holes. Identifying these unusually X-ray bright sources and measuring their optical properties can provide valuable constraints on the progenitors of gravitational wave sources. We compare observations of these sources to the twenty previously studied GCULXs from five other early-type galaxies, and find that GCULXs in NGC 4261 are of similar colour and luminosity and do not significantly deviate from the rest of the sample in terms of distance from the galaxy centre or X-ray luminosity. Both the GCULX and GCLMXB populations of NGC 4261 show long-term variability; the former may have implications for fast radio bursts originating in globular clusters and the latter will likely introduce additional scatter into the low mass end of GCLMXB X-ray luminosity functions.
Clouds accreting from the IGM are not able to feed the star formation of low-redshift disc galaxies
Authors: Afruni Andrea , Pezzulli Gabriele , Fraternali Filippo , Grønnow Asger 
Published: July 2023

ABSTRACT
Galactic halos accrete material from the intergalactic medium (IGM) and part of this accretion is expected to be in the form of cool (T ∼ 104 K) gas. A signature of this process could reside in the detection of numerous clouds in the circumgalactic medium (CGM). However, whether this material is able to accrete onto the galaxies and feed their star formation or, instead, evaporates into the CGM hot phase (corona, T ∼ 106 K), is not yet understood. Here, we investigate the evolution of cool CGM clouds accreted from the IGM and falling through the hot corona of low-redshift disc galaxies, using 3D high-resolution hydrodynamical simulations. We include the effects of gravity due to the dark matter halo, isotropic thermal conduction, radiative cooling, and an ionizing UV background. We explored different values of parameters such as the halo mass, coronal mass, initial cloud velocity and strength of the thermal conduction. We find that the clouds lose the vast majority of their mass at distances larger than half of the galaxy virial radius and are completely dissolved in the corona before reaching the central galaxy. Resolving the Field length with at least 5–7 cells is crucial to correctly capture the evolution of the infalling cool gas. Our results indicate that cool IGM accretion can not feed star formation in z ∼ 0 star-forming galaxies in halos with masses of 1011.9 M⊙ or above. This suggests that present-day massive star-forming galaxies can sustain their star formation only via the spontaneous or induced cooling of their hot corona.
Fuzzy dark matter in relativistic stars
Authors: Rezaei Zeinab 
Published: July 2023

ABSTRACT
Fuzzy dark matter (FDM), a practical alternative to cold dark matter, can exist in compact stars. Here, applying the FDM equation of state (EoS) constrained by cosmic microwave background and large-scale structure data, we calculate the structure of relativistic stars in the presence of FDM. For this aim, the EoS for the visible matter in neutron stars, quark stars, and hybrid stars from the observational data are employed. A piecewise polytropic EoS constrained by the observational data of GW170817 and the data of six low-mass X-ray binaries with thermonuclear burst or the symmetry energy of the nuclear interaction describes the neutron star matter. For quark star matter, we apply the EoSs within the Bayesian statistical approach using the mass and radius measurements of PSR J0030+0451 from NICER. Employing the two-fluid formalism, we study the structure of FDM admixed relativistic stars.
Gravitational wave spectral synthesis
Authors: van Zeist Wouter G J , Eldridge J J , Tang Petra N 
Published: July 2023

ABSTRACT
We study the Laser Interferometer Space Antenna (LISA) sources that arise from isolated binary evolution, and how these depend on age and metallicity, using model stellar populations from bpass. We model these as single-aged populations which are analogous to star clusters. We calculate the combined gravitational wave (GW) spectrum of all the binaries within these model clusters, including all types of compact binaries as well as those with living stars. These results allow us to evaluate the detectability of star clusters with LISA. We find at late times the dominant sources are WD–WD binaries by factors of 50–200, but at times between 108 and 109 yr we find a significant population of NS–WD and BH–WD binaries (2–40 per 106 M⊙), which is related to the treatment of mass transfer and common-envelope events in bpass, wherein mass transfer is relatively likely to be stable. Metallicity also has an effect on the GW spectrum and on the relative dominance of different types of binaries. Using the information about known star clusters will aid the identification of sky locations where one could expect LISA to find GW sources.
Observational predictions for Thorne–Żytkow objects
Authors: Farmer R , Renzo M , Götberg Y , Bellinger E , Justham S , de Mink S E 
Published: July 2023

ABSTRACT
Thorne–Żytkow objects (TŻO) are potential end products of the merger of a neutron star with a non-degenerate star. In this work, we have computed the first grid of evolutionary models of TŻOs with the MESA stellar evolution code. With these models, we predict several observational properties of TŻOs, including their surface temperatures and luminosities, pulsation periods, and nucleosynthetic products. We expand the range of possible TŻO solutions to cover $3.45 \lesssim \rm {\log \left(T_{eff}/K\right)}\lesssim 3.65$ and $4.85 \lesssim \rm {\log \left(L/L_{\odot }\right)}\lesssim 5.5$. Due to the much higher densities our TŻOs reach compared to previous models, if TŻOs form we expect them to be stable over a larger mass range than previously predicted, without exhibiting a gap in their mass distribution. Using the GYRE stellar pulsation code we show that TŻOs should have fundamental pulsation periods of 1000–2000 d, and period ratios of ≈0.2–0.3. Models computed with a large 399 isotope fully coupled nuclear network show a nucleosynthetic signal that is different to previously predicted. We propose a new nucleosynthetic signal to determine a star’s status as a TŻO: the isotopologues $\mathrm{^{44}Ti} \rm {O}_2$ and $\mathrm{^{44}Ti} \rm {O}$, which will have a shift in their spectral features as compared to stable titanium-containing molecules. We find that in the local Universe (∼SMC metallicities and above) TŻOs show little heavy metal enrichment, potentially explaining the difficulty in finding TŻOs to-date.
The distribution of accretion rates as a diagnostic of protoplanetary disc evolution
Authors: Alexander Richard , Rosotti Giovanni , Armitage Philip J , Herczeg Gregory J , Manara Carlo F , Tabone Benoît 
Published: July 2023

ABSTRACT
We show that the distribution of observed accretion rates is a powerful diagnostic of protoplanetary disc physics. Accretion due to turbulent (‘viscous’) transport of angular momentum results in a fundamentally different distribution of accretion rates than accretion driven by magnetized disc winds. We find that a homogeneous sample of ≳300 observed accretion rates would be sufficient to distinguish between these two mechanisms of disc accretion at high confidence, even for pessimistic assumptions. Current samples of T Tauri star accretion rates are not this large, and also suffer from significant inhomogeneity, so both viscous and wind-driven models are broadly consistent with the existing observations. If accretion is viscous, the observed accretion rates require low rates of disc photoevaporation (≲10−9 M⊙ yr−1). Uniform, homogeneous surveys of stellar accretion rates can therefore provide a clear answer to the long-standing question of how protoplanetary discs accrete.
Tidal dissipation due to the elliptical instability and turbulent viscosity in convection zones in rotating giant planets and stars
Authors: de Vries Nils B , Barker Adrian J , Hollerbach Rainer 
Published: July 2023

ABSTRACT
Tidal dissipation in star–planet systems can occur through various mechanisms, among which is the elliptical instability. This acts on elliptically deformed equilibrium tidal flows in rotating fluid planets and stars, and excites inertial waves in convective regions if the dimensionless tidal amplitude (ϵ) is sufficiently large. We study its interaction with turbulent convection, and attempt to constrain the contributions of both elliptical instability and convection to tidal dissipation. For this, we perform an extensive suite of Cartesian hydrodynamical simulations of rotating Rayleigh–Bénard convection in a small patch of a planet. We find that tidal dissipation resulting from the elliptical instability, when it operates, is consistent with ϵ3, as in prior simulations without convection. Convective motions also act as an effective viscosity on large-scale tidal flows, resulting in continuous tidal dissipation (scaling as ϵ2). We derive scaling laws for the effective viscosity using (rotating) mixing-length theory, and find that they predict the turbulent quantities found in our simulations very well. In addition, we examine the reduction of the effective viscosity for fast tides, which we observe to scale with tidal frequency (ω) as ω−2. We evaluate our scaling laws using interior models of Hot Jupiters computed with mesa. We conclude that rotation reduces convective length-scales, velocities, and effective viscosities (though not in the fast tides regime). We estimate that elliptical instability is efficient for the shortest period Hot Jupiters, and that effective viscosity of turbulent convection is negligible in giant planets compared with inertial waves.
Taking the long view on short-run marginal emissions: how much carbon does flexibility and energy storage save?
Authors: Grunewald Phil , Aunedi Marko , Nosratabadi Seyyed Mostafa , Morstyn Thomas , Savelli Iacopo , Kumtepeli Volkan , Howey David 
Published: July 2023

ABSTRACT
Grid-scale electricity storage will play a crucial role in the transition of power systems towards zero carbon. During the transition, investments need to be channeled towards technologies and locations that enable zero carbon operation in the long term, while also delivering security of supply and value for money. We discuss metrics and market signals that are needed to guide this transition towards clean, secure and affordable solutions. Paradoxically, carbon metrics play an important role, but become less effective as a decision tool once the system approaches zero carbon. We critically assess the role of marginal and average emission and question the allocation of marginal emissions in systems where combinations of renewables and storage deliver flexibility. We conclude that, for strategic investments, short-term market signals may not always deliver sufficiently fast or far-sighted outcomes and operational decisions need to consider the merit order of demand as well as supply.
Higgs response and pair condensation energy in superfluid nuclei
Authors: Takahashi Kengo , Matsuda Yusuke , Matsuo Masayuki 
Published: July 2023

Abstract
The pairing correlation in nuclei causes a characteristic excitation, known as the pair vibration, which is populated by the pair transfer reactions. Here we introduce a new method of characterizing the pair vibration by employing an analogy to the Higgs mode, which emerges in infinite superconducting/superfluid systems as a collective vibrational mode associated with the amplitude oscillation of the Cooper pair condensate. The idea is formulated by defining a pair-transfer probe, the Higgs operator, and then describing the linear response and the strength function to this probe. We will show that the pair condensation energy in nuclei can be extracted with use of the strength sum and the static polarizability of the Higgs response. In order to demonstrate and validate the method, we perform numerical analysis for Sn isotopes based on the quasi-particle random phase approximation to the Skyrme–Hartree–Fock–Bogoliubov model. We discuss the possibility of applying this new scheme to pair-transfer experiments.
The influence of biological DMARDs on aseptic arthroplasty loosening: a retrospective cohort study
Authors: Schreiner Markus M , Straub Jennifer , Apprich Sebastian , Staats Kevin , Windhager Reinhard , Aletaha Daniel , Böhler Christoph 
Published: July 2023

Abstract

Objective
To investigate whether biological DMARDs affect the risk of aseptic loosening after total hip/knee arthroplasty (THA/TKA) in patients with RA.

Methods
We retrospectively identified all patients suffering from RA who underwent THA/TKA at our academic centre between 2002 and 2015 and linked them with an existing prospective observational RA database at our institution. The risk of aseptic loosening was estimated using radiological signs of component loosening (RCL). A time-dependent Cox regression analysis was used to compare the risk of implant loosening between patients treated with traditional DMARDS and biological DMARDs, or alternately both over time.

Results
A total of 155 consecutive total joint arthroplasties (TJAs) (103 TKA vs 52 THA) was retrospectively included in the study. Mean age at implantation was 59 ± 13 years. Mean follow-up time was 69 ± 43 months. Overall, 48 (31%) TJAs showed signs of RCL, with 28 (27.2%) RCLs occurring after TKA compared with 20 after THA (38.5%). A significant difference regarding the incidence of RCL between the traditional DMARDs group (39 cases of RCL, 35%) and the biological DMARDs group (nine cases of RCL, 21%) (P = 0.026) was observed using the log-rank test. This was also true when using a time-dependent Cox regression with therapy as well as arthroplasty location (hip vs knee) as variables (P = 0.0447).

Conclusion
Biological DMARDs may reduce the incidence of aseptic loosening after TJA in patients with RA compared with traditional DMARDs. This effect seems to be more pronounced after TKA than THA.
Effect of mindfulness on sexual self-efficacy and sexual satisfaction among Iranian postmenopausal women: a quasi-experimental study
Authors: Khazaeian Somayyeh , Navidian Ali , Rahiminezhad Maryam 
Published: July 2023

Abstract

Background
Menopause with anatomical, physiological, and psychological changes can affect sexual satisfaction and consequently the quality of life.

Aims
The study sought to evaluate the effects of mindfulness-based counseling on sexual self-efficacy and sexual satisfaction among Iranian postmenopausal women.

Methods
This quasi-experimental study was conducted on 110 women who were assigned to an intervention group (n = 55) and a control group (n = 55). The intervention group received 8 sessions of mindfulness-based training and daily mindfulness exercises. Data collection tools included questionnaires of demographics and midwifery, sexual self-efficacy, and sexual satisfaction. They were completed before and 8 weeks after the intervention. The collected data were analyzed through a t test, a chi-square test, and repeated-measures analysis of variance.

Outcomes
Changes in sexual self-efficacy and sexual satisfaction scores were evaluated.

Results
The mindfulness-based intervention significantly improved sexual self-efficacy (F = 146.98, P = .000, ƞ2 = 0.576) and sexual satisfaction (F = 129.47, P = .000, ƞ2 = 0.545) over time. The mean scores of sexual self-efficacy (17.03 ± 2.08) and sexual satisfaction (87.94 ± 8.26) in the intervention group increased after the intervention as opposed to the mean scores of sexual self-efficacy (12.65 ± 1.70) and sexual satisfaction (76.61 ± 6.45) in the control group.

Clinical Implications
Mindfulness training can improve sexual self-efficacy and sexual satisfaction in postmenopausal women.

Strengths and Limitations
The intervention was implemented on a population of menopausal women in a culture in which the expression of sexual issues is taboo and has not been noticed in the past. The main limitation of this study was self-reporting, which may have affected the responses. The next limitation was the nonrandomized controlled design. Finally, the research sample included menopausal women who were heterosexual and married. Hence, the findings may not be generalizable to more diverse samples. In this study, psychological maladjustment or psychological distress was not analyzed. They should also be considered in future research.

Conclusion
According to the results, it is advisable to employ mindfulness-based intervention in routine care, because it can improve different aspects of menopausal women’s life.
Uterine defects and estradiol‐dependent development of oviductal diverticula in mice lacking the SMAD4 C‐terminal Mad homology 2 domain
Authors: Petit Fabrice G. , Kervarrec Christine , Allais‐Bonnet Aurélie , Evrard Bertrand , Chalmel Frédéric , Deng Chuxia , Jamin Soazik P. 
Published: July 2023

AbstractIn female mammals, the oviduct and uterus are essential sites for female and male gamete transport, fertilization, implantation, and maintenance of a successful pregnancy. To delineate the reproductive function of Mothers against decapentaplegic homolog 4 (Smad4), we specifically inactivated Smad4 in ovarian granulosa cells and, oviduct and uterine mesenchymal cells using the Amhr2‐cre mouse line. Deletion of exon 8 of Smad4 results in the production of an MH2‐truncated SMAD4 protein. These mutant mice are infertile due to the development of oviductal diverticula and defects during the implantation process. The ovaries are fully functional as demonstrated in an ovary transfer experiment. The development of oviductal diverticula occurs shortly after puberty and is dependent on estradiol. The diverticula interfere with sperm migration and embryo transit to the uterus, reducing the number of implantation sites. Analysis of the uterus shows that, even if implantation occurs, decidualization and vascularization are defective resulting in embryo resorption as early as the seventh day of pregnancy. Thus, Smad4 plays an important function in female reproduction by controlling the structural and functional integrity of the oviduct and uterus.