bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sistem Informasi Geografis Mencari Rute Terpendek Pada Pemetaan SMP di Kecamatan Mustikajaya Dengan Algoritma A-Star A(*) Berbasis Web
Authors: Novandra Deka Darma , Putra Tri Dharma , Mayadi Mayadi 
Published: July 2023

Many parents have few references to send their children to school, and are only based on suggestions or invitations from those closest to them. Lack of information can be one of the reasons for the lack of references for parents to choose a junior high school for their child. The lack of information regarding the location of junior high schools is the reason for the lack of references for parents to send their children to school. Based on the existing problems, the authors propose a web-based geographic information system that uses the A-Star Algorithm (A*) to be used as a means of information and also to add references for parents/guardians. The A-Star (A*) algorithm is a method for searching for information about the distance to reach a destination by selecting the closest route.
Keywords: A-Star Algorithm (A*), Closest Path, Middle School, Mustikajaya, Web

Abstrak
Banyak orang tua yang memiliki sedikit referensi untuk menyekolahkan anaknya, dan hanya berdasarkan saran atau usulan dari orang terdekat. Kurangnya informasi bisa menjadi salah satu penyebab kurangnya referensi orang tua untuk memilih sekolah menengah pertama untuk anaknya. Minimnya informasi mengenai lokasi sekolah memengah pertama menjadi penyebab sedikitnya referensi orang tua dalam menyekolahkan anaknya. Berdasarkan masalah yang ada peneliti mengusulkan sebuah sistem informasi geografis berbasis web yang menggunakan Algoritma A-Star (A*) untuk dijadikan sarana informasi dan juga untuk menambah referensi para orang tua/wali. Algoritma A-Star (A*) adalah metode untuk melakukan pencarian informasi mengenai jarak untuk mencapai tujuan dengan pemilihan rute terdekat.
Kata Kunci: Algoritma A-Star (A*), Jalur Terdekat Mustikajaya, SMP, Web
Electric‐Dipole Gated Two Terminal Phototransistor for Charge‐Coupled Device
Authors: Imran Ali , Zhu Qinghai , Sulaman Muhammad , Bukhtiar Arfan , Xu Mingsheng 
Published: July 2023

AbstractThe demand for charge‐coupled device (CCD) imagers has surged exponentially during the last decade owing to their exceptionally high quality and low noise imaging. However, they are still confronting the performance constraints of high operation power, low speed, and limited charge integration. Here, the electric‐dipole gated phototransistor operation without external gate bias is reported by using high‐k HfO2 dielectric material. The electrostatic coupling of photogenerated charges from the Si with the graphene channel through a 10 nm HfO2 layer is demonstrated. The device exhibits remarkable performance in the broadband spectrum (266–1342 nm) at low drain bias voltage. The high values of responsivity, external quantum efficiency, and detectivity of 3.7 × 103 A W−1, 0.72 × 104, and 6.20 × 1013 cmHz½ W−1, respectively, for 800 nm wavelength and 3.3 × 103 A W−1, 1.31 × 104, and 5.61 × 1013 cmHz½ W−1, respectively, for 400 nm wavelength without gate are achieved. This discovery may potentially eliminate the requirement for gate terminals from commercial CCD devices. The power efficient features of this gateless image sensor can be fabricated at the industrial scale for the future machine vision market.
Leveraging Thermal Properties Data toward Efficient Photothermal Therapy of Mammary Glands
Authors: Huang Dezhao , Fang Yuxin , Zheng Weijie , Peng Yuxuan , Liu Jianhua , She Jinjuan , Chen Chuang , Yue Yanan 
Published: July 2023

AbstractPhotothermal therapy (PTT) is gaining wide attention in oncological applications. Nevertheless, its efficacy is still being questioned due to the potential deleterious thermal impact on healthy tissues. The comprehension of tissue thermal properties and their role in photothermal heat transfer is critical. In this study, the thermal conductivity of murine mammary gland (MG) tissues (both tumorous and normal) is initially characterized as a function of time post‐tumor cell inoculation. Notably, the tumorous MGs exhibit a mean thermal conductivity of 0.41 ± 0.013 W m−1 K−1, a 28% increase compared to the normal tissue (0.32 ± 0.003 W m−1 K−1). A self‐developed ultra‐fast hot‐wire technique is employed to assess the marginal temperature elevation in thin MG samples. These experimental findings suggest that the thermal conductivity escalates as the tumor advances. Employing a constant‐power laser, variations in therapeutic outcomes are attributed to the synergistic effect of augmented thermal conductivity and tumoral volume. Importantly, these data substantiate that the early commencement of photothermal irradiation effectively stymies tumor advancement. These insights can foster improved early‐stage PTT by calibrating irradiation schedules contingent on meticulous thermal property assessments, thus optimizing therapeutic results.
Alternative reproductive tactics of unflanged and flanged male orangutans revisited
Authors: Kunz Julia A. , Duvot Guilhem J. , Ashbury Alison M. , Willems Erik P. , Spillmann Brigitte , Dunkel Lynda P. , bin Abdullah Misdi , Schuppli Caroline , Vogel Erin R. , Utami Atmoko Sri Suci , van Noordwijk Maria A. , van Schaik Carel P. 
Published: July 2023

AbstractIn many slowly developing mammal species, males reach sexual maturity well before they develop secondary sexual characteristics. Sexually mature male orangutans have exceptionally long periods of developmental arrest. The two male morphs have been associated with behavioral alternative reproductive tactics, but this interpretation is based on cross‐sectional analyses predominantly of Northwest Sumatran populations. Here we present the first longitudinal analyses of behavioral changes of 10 adult males that have been observed in both unflanged and flanged morph. We also analyzed long‐term behavioral data on an additional 143 individually identified males from two study sites, Suaq (Sumatra, Pongo abelii) and Tuanan (Borneo, Pongo pygmaeus wurmbii), to assess male mating tactics cross‐sectionally in relation to population, male morph (unflanged and flanged), and other socio‐ecological factors. Both our longitudinal and cross‐sectional results confirm and refine previous cross‐sectional accounts of the differences in mating tactics between the unflanged and the flanged male morphs. In the unflanged morph, males exhibit higher sociability, particularly with females, and higher rates of both copulation and sexual coercion than in the flanged morph. Based on our results and those of previous studies showing that females prefer flanged males, and that flanged males have higher reproductive success, we conclude that unflanged males face a trade‐off between avoiding male‐male contest competition and gaining mating access to females, and thus follow a “best‐of‐a‐bad‐job” mating strategy.
Polymers with Intrinsic Microporosity as Solid Ion Conductors for Solid‐State Lithium Batteries
Authors: Wang Xiao‐Xue , Song Li‐Na , Zheng Li‐Jun , Guan De‐Hui , Miao Cheng‐Lin , Li Jia‐Xin , Li Jian‐You , Xu Ji‐Jing 
Published: July 2023

AbstractSolid‐state electrolytes (SSEs) with high ionic conductivity and superior stability are considered to be a key technology for the safe operation of solid‐state lithium batteries. However, current SSEs are incapable of meeting the requirements for practical solid‐state lithium batteries. Here we report a general strategy for achieving high‐performance SSEs by engineering polymers of intrinsic microporosity (PIMs). Taking advantage of the interconnected ion pathways generated from the ionizable groups, high ionic conductivity (1.06×10−3 S cm−1 at 25 °C) is achieved for the PIMs‐based SSEs. The mechanically strong (50.0 MPa) and non‐flammable SSEs combine the two superiorities of outstanding Li+ conductivity and electrochemical stability, which can restrain the dendrite growth and prevent Li symmetric batteries from short‐circuiting even after more than 2200 h cycling. Benefiting from the rational design of SSEs, PIMs‐based SSEs Li‐metal batteries can achieve good cycling performance and superior feasibility in a series of withstand abuse tests including bending, cutting, and penetration. Moreover, the PIMs‐based SSEs endow high specific capacity (11307 mAh g−1) and long‐term discharge/charge stability (247 cycles) for solid‐state Li−O2 batteries. The PIMs‐based SSEs present a powerful strategy for enabling safe operation of high‐energy solid‐state batteries.
Atomic layer deposition of ZnO on PLA/TiO2 bionanocomposites: Evaluation of surface chemistry and physical properties toward food packaging applications
Authors: Barmpaki Aimilia A. , Zavvou Evangelia E. , Drivas Charalampos , Papapetros Konstantinos , Sygellou Labrini , Andrikopoulos Konstantinos S. , Kennou Stella , Andritsos Nikolaos D. , Giannakas Aris , Salmas Constantinos E. , Ladavos Athanasios , Svarnas Panagiotis , Karahaliou Panagiota K. , Krontiras Christoforos A. 
Published: July 2023

AbstractThe impact of titanium dioxide (TiO2) on the physical properties of poly(lactic acid) (PLA) is explored, along with the combined effect of Atomic Layer Deposition of zinc oxide (ZnO) on the nanocomposite films' surface. PLA/TiO2 bionanocomposites are prepared via melt‐extrusion and characterized in terms of their morphological, thermal, and mechanical properties. Homogeneous dispersion of the filler offers enhanced mechanical performance for samples up to 5 wt% in TiO2 content. Thermal stability of PLA is also slightly improved upon increasing TiO2 content. This work also demonstrates that surface modification of PLA/TiO2 films employing Atomic Layer Deposition of zinc oxide enhances hydrophobicity, while antimicrobial activity, although mild, appears enhanced for coated samples. Water vapor permeability is retained in both coated and uncoated nanocomposites. Surface characterization of the studied specimens, by x‐ray photoelectron spectroscopy and scanning electron microscopy, reveals subsurface diffusion and reaction of the depositing compounds within PLA, leading to a different surface chemistry involving Zn(OH)2. This study gives valuable insights on the parameters affecting the atomic layer deposition of inorganic coatings on a polymeric substrate in the presence of nanoinclusions and, therefore, on the physical properties of the coated films, providing the pathway for their exploitation in food packaging applications.
Distance versus face‐to‐face education of gross anatomy for dental hygiene students: Perceptions and academic achievements of learners
Authors: Kim Da‐Hye 
Published: July 2023

AbstractThe provision of distance education has increased rapidly over the past few years owing to the COVID‐19 pandemic. The core of gross anatomy distance education is three‐dimensional (3D) visualization of anatomical structures, and the use of simple 3D visualization tools has increased as distance education has become more popular. The purpose of this study was to establish a more effective operation plan in dental hygiene by investigating learners' opinions about distance education of gross anatomy and 3D visualization tools, and by comparing and analyzing their academic achievements. The study involved 250 students and comprised an analysis of 120 students who took a head and neck anatomy class at the Department of Dental Hygiene at D University via distance learning during 2020–2022, and 130 graduates who had completed the class via face‐to‐face learning during 2015–2017. An online survey of 120 of the enrolled students comprised 10 questions asking for opinions on the head and neck anatomy distance learning classes, five questions on the 3D visualization tool, and five on general characteristics. Overall, the learners had positive perceptions of distance education for head and neck anatomy and the 3D visualization tool. Among the education methods compared, they generally preferred blended learning (n = 47, 39.2%). There was a significant preference for the distance learning method of asynchronous classes (n = 86, 94.5%). Analysis of academic achievements according to whether or not distance education was conducted revealed a significantly higher score in the face‐to‐face class group (P < 0.05). A blended learning method can be effective in increasing learner satisfaction and improving academic achievement in gross anatomy classes on dental hygiene. It is suggested that theoretical material should be learned through asynchronous content and knowledge expanded through small‐group activities during face‐to‐face learning. This will help establish a standard model for teaching of gross anatomy in dental hygiene in the postpandemic era.
Relational transformation or resolution only? A quantitative analysis of mediator and disputant behaviors, and mediation outcome
Authors: Tsuruhara Toshiyasu , Cremin Hilary 
Published: July 2023

AbstractThis research quantitatively investigated the behaviors observed in mediation. We coded 16 mediation sessions recorded at a secondary school in the United Kingdom as relational transformation or resolution only and examined if the frequencies of the behaviors were significantly different between these two categories. We also investigated how the characteristics of their behaviors were correlated. Results indicated that the frequencies of the mediator's empathetic and the disputant's open, expansive, and defiant behaviors were significantly different between the two categories. Our findings also suggested several positive correlations between the behaviors, including the disputant's open and expansive, open and the mediator's empathetic, expansive and the mediator's eliciting, and negative between open and the mediator's directive, and defiant and the mediator's eliciting behaviors. Our findings mostly supported what has been widely discussed among the mediation researchers and practitioners—active listening, empathy, and impartiality, but also found a mutually enhancing relationship between the disputant's open and expansive behaviors. For relational transformation, we argue that the mediator should demonstrate empathy to help the disputant's open expression while asking eliciting questions to encourage their mutual acknowledgment and preclude defiance.
Homocysteine metabolites inhibit autophagy, elevate amyloid beta, and induce neuropathy by impairing Phf8/H4K20me1‐dependent epigenetic regulation of mTOR in cystathionine β‐synthase‐deficient mice
Authors: Witucki Łukasz , Jakubowski Hieronim 
Published: July 2023

AbstractThe loss of cystathionine β‐synthase (CBS), an important homocysteine (Hcy)‐metabolizing enzyme or the loss of PHF8, an important histone demethylase participating in epigenetic regulation, causes severe intellectual disability in humans. Similar neuropathies were also observed in Cbs−/− and Phf8−/− mice. How CBS or PHF8 depletion can cause neuropathy was unknown. To answer this question, we examined a possible interaction between PHF8 and CBS using Cbs−/− mouse and neuroblastoma cell models. We quantified gene expression by RT‐qPCR and western blotting, mTOR‐bound H4K20me1 by chromatin immunoprecipitation (CHIP) assay, and amyloid β (Aβ) by confocal fluorescence microscopy using anti‐Aβ antibody. We found significantly reduced expression of Phf8, increased H4K20me1, increased mTOR expression and phosphorylation, and increased App, both on protein and mRNA levels in brains of Cbs−/− mice versus Cbs+/− sibling controls. Autophagy‐related Becn1, Atg5, and Atg7 were downregulated while p62, Nfl, and Gfap were upregulated on protein and mRNA levels, suggesting reduced autophagy and increased neurodegeneration in Cbs−/− brains. In mouse neuroblastoma N2a or N2a‐APPswe cells, treatments with Hcy‐thiolactone, N‐Hcy‐protein or Hcy, or Cbs gene silencing by RNA interference significantly reduced Phf8 expression and increased total H4K20me1 as well as mTOR promoter‐bound H4K20me1. This led to transcriptional mTOR upregulation, autophagy downregulation, and significantly increased APP and Aβ levels. The Phf8 gene silencing increased Aβ, but not APP, levels. Taken together, our findings identify Phf8 as a regulator of Aβ synthesis and suggest that neuropathy of Cbs deficiency is mediated by Hcy metabolites, which transcriptionally dysregulate the Phf8 → H4K20me1 → mTOR → autophagy pathway thereby increasing Aβ accumulation.
From two sensors to a single sensor: Better understanding of oxygen–sulfide interfaces
Authors: Steininger Fabian , Veerubhotla Ramya , Revsbech Niels Peter , Marzocchi Ugo , Koren Klaus 
Published: July 2023

AbstractIntense biogeochemical transformations in sediments and biofilms may occur over sub‐mm distances. Our current understanding of those transformations in such narrowly stratified environments has been facilitated by the introduction of microsensors. Until now most studies have been conducted using individual sensors for the various chemical species, and careful vertical alignment of the sensor tips is then essential for the meaningful interpretation of the resulting data. For instance, the determination of total dissolved sulfide (TDS) at high resolution requires perfect alignment of sensors for H2S and pH, as the pKa for H2S is close to ambient pH. In this study, we show how a recently developed TDS sensor and a new combined H2S/O2microsensor can improve the analysis of sulfidic environments including the oxygen–sulfide interface. The TDS sensor does not require pH correction unlike the conventional H2S sensor, and it thus eliminates the need for a simultaneous pH measurement. The combined sensor allows for perfect alignment of H2S and O2micro profiles and makes it possible to not only more accurately estimate fluxes, but also to determine overlapping zones of oxygen and dissolved sulfide at very high resolution.
Representations of science content in a primary classroom: Combining long and short timescales for multimodal analysis
Authors: Danielsson Kristina , Jeppsson Fredrik , Nestlog Ewa B. , Tang Kok‐Sing 
Published: July 2023

AbstractThis study reports on a case study about multimodal work in a primary physics classroom focusing on forces. Previous research reports that students benefit from multimodal work in science classrooms. Yet, few systematic studies have been performed to reveal how students represent their experiences and ideas of science phenomena over time within and across different semiotic modes (e.g., through action, speech, writing, and image, including multimodal ensembles). The design of the lessons was built around a number of experimental activities, starting with a puzzling phenomenon and where students for each experiment predicted, observed, described, and tried to come up with explanations. Based on social‐semiotics, we combined analysis at an overall level (long timescale and large grain size) and a detailed level (short timescale and small grain size) to shed light on how the science content was represented within and between modes over the teaching and learning period, and what content was expressed in these representations. Our findings reveal how students moved from focusing on attributes such as a “heavy” regarding artifacts used in the experiments, towards the central physics processes, such as one object exerting force on another object. Furthermore, we were able to detect that such “signs of learning” were shown in students’ small‐group discussions and multimodal texts following a carefully orchestrated multimodal exposition by the teacher. Hence, such a careful multimodal orchestration appeared to be critical for the students’ meaning‐making about the science content.
The dynamics of psychological attributes and symptomatic comorbidity of depression in children and adolescents
Authors: Sánchez Hernández Milagros Ocalin , Holgado-Tello Francisco Pablo , Carrasco Miguel Á. 
Published: July 2023

Abstract
Purpose
This investigation aimed to explore attribute dynamics and symptomatic comorbidity of depression with internalizing, externalizing, and other personal–contextual problems in children and adolescents from a network analysis.

Methods
We tested an attribute network of regularized partial correlations, standard and alternative centrality measures, and comorbidity bridge symptoms according to centrality bridge measures.

Results
Regularized partial correlation network and a centrality measures graph shown the prominent position of social problems and anxiety–depression. Minimum spanning tree (MST) found a hierarchical dynamics between attributes where mixed anxiety–depression was identified as the core and the other attributes were hierarchically connected to it by being positioned in six branches that are differentiated according to their theoretical contents. The most central connections are established with the attributes of their own community or theoretical groups, and 37 bridge symptoms were identified in all networks.

Conclusions
A significant role of mixed anxiety depression as an activator and intermediary of psychopathologies was supported as a central attribute of internalizing problems. Aggressive behavior as part of the broad externalizing dimension was one of the constructs that most intensively activate the network, and social problems were also distinguished as a relevant factor not only in terms of connections and central attributes but also in terms of bridge symptoms and comorbidity. This framework extends to the study of symptomatic “comorbidity.”
Antibody Fc-binding profiles and ACE2 affinity to SARS-CoV-2 RBD variants
Authors: Haycroft Ebene R. , Davis Samantha K. , Ramanathan Pradhipa , Lopez Ester , Purcell Ruth A. , Tan Li Lynn , Pymm Phillip , Wines Bruce D. , Hogarth P. Mark , Wheatley Adam K. , Juno Jennifer A. , Redmond Samuel J. , Gherardin Nicholas A. , Godfrey Dale I. , Tham Wai-Hong , Selva Kevin John , Kent Stephen J. , Chung Amy W. 
Published: July 2023

AbstractEmerging SARS-CoV-2 variants, notably Omicron, continue to remain a formidable challenge to worldwide public health. The SARS-CoV-2 receptor-binding domain (RBD) is a hotspot for mutations, reflecting its critical role at the ACE2 interface during viral entry. Here, we comprehensively investigated the impact of RBD mutations, including 5 variants of concern (VOC) or interest—including Omicron (BA.2)—and 33 common point mutations, both on IgG recognition and ACE2-binding inhibition, as well as FcγRIIa- and FcγRIIIa-binding antibodies, in plasma from two-dose BNT162b2-vaccine recipients and mild-COVID-19 convalescent subjects obtained during the first wave using a custom-designed bead-based 39-plex array. IgG-recognition and FcγR-binding antibodies were decreased against the RBD of Beta and Omicron, as well as point mutation G446S, found in several Omicron sub-variants as compared to wild type. Notably, while there was a profound decrease in ACE2 inhibition against Omicron, FcγR-binding antibodies were less affected, suggesting that Fc functional antibody responses may be better retained against the RBD of Omicron in comparison to neutralization. Furthermore, while measurement of RBD–ACE2-binding affinity via biolayer interferometry showed that all VOC RBDs have enhanced affinity to human ACE2, we demonstrate that human ACE2 polymorphisms, E35K (rs1348114695) has reduced affinity to VOCs, while K26R (rs4646116) and S19P (rs73635825) have increased binding kinetics to the RBD of VOCs, potentially affecting virus–host interaction and, thereby, host susceptibility. Collectively, our findings provide in-depth coverage of the impact of RBD mutations on key facets of host–virus interactions.