bluuebunny/crossref_metadata_2025_split huggingface dataset:
Harmonic Mode‐Locked Er‐Doped Fiber Laser Based on a Microfiber‐Based PbS Nanoparticle Saturable Absorber
Authors: Nie Liang , Wang Lu , Liu Xiaoyu , Luo Wenfeng , Wang Chong , Wang Wei , Feng Jiangjiang , Gao Ge , Li Xiaohui , Zhang Kai 
Published: July 2023

AbstractLead sulfide (PbS) is a nanomaterial with excellent optical and chemical properties, such as a narrow bandgap (0.37 eV), high thermal damage threshold, and high stability. Obviously, it is appropriate as a saturable absorber (SA) device for ultrafast photonics. However, PbS nanoparticles (NPs) as the SA of ultrashort harmonic mode‐locked pulse still haven't been demonstrated at present. In this paper, the PbS NPs are made into an SA‐device‐based microfiber by optical deposition method and connected in an integrated Erbium‐doped fiber laser. And both characteristics and nonlinear optical properties of PbS NPs have been systemically investigated. A fundamental frequency mode‐locked pulsed laser is proposed, whose central wavelength is 1560 nm, and the pulse width is 1 ps. In addition, high repetition rate operations are achieved, with a maximum repetition rate of 833 MHz. This is the first time that PbS NPs are used to generate 96th‐order harmonic mode‐locking, and the corresponding pulse duration is 987 fs. It is demonstrated that PbS NPs are a kind of SA photonic material with excellent performance. It can improve the communication capacity by applying fiber communication, and it has potential application value even in material processing and optical comb.
An analysis of patterns of distribution of buprenorphine in the United States using ARCOS, Medicaid, and Medicare databases
Authors: Hsu Zhi‐Shan , Warnick Justina A. , Harkins Tice R. , Sylvester Briana E. , Bharati Neal K. , Eley leTausjua B. , Nichols Stephanie D. , McCall Kenneth , Piper Brian J. 
Published: July 2023

AbstractOpioid overdose remains a problem in the United States despite pharmacotherapies, such as buprenorphine, in the treatment of opioid use disorder. This study characterized changes in buprenorphine use. Using the Drug Enforcement Administration's ARCOS, Medicaid, and Medicare claims databases, patterns in buprenorphine usage in the United States from 2018 to 2020 were analyzed by examining percentage changes in total grams distributed and changes in grams per 100 K people in year‐to‐year usage based on ZIP code and state levels. For ARCOS from 2018 to 2019 and 2019 to 2020, total buprenorphine distribution in grams increased by 16.2% and 12.6%, respectively. South Dakota showed the largest statewide percentage increase in both 2018–2019 (66.1%) and 2019–2020 (36.7%). From 2018 to 2019, the ZIP codes ND‐577 (156.4%) and VA‐222 (−82.1%) had the largest and smallest percentage changes, respectively. From 2019 to 2020, CA‐932 (250.2%) and IL‐603 (−36.8%) were the largest and smallest, respectively. In both 2018–2019 and 2019–2020, PA‐191 had the second highest increase in grams per 100K while OH‐452 was the only ZIP code to remain in the top three largest decreases in grams per 100K in both periods. Among Medicaid patients in 2018, there was a nearly 2000‐fold difference in prescriptions per 100k Medicaid enrollees between Kentucky (12 075) and Nebraska (6). Among Medicare enrollees in 2018, family medicine physicians and other primary care providers were the top buprenorphine prescribers. This study not only identified overall increases in buprenorphine availability but also pronounced state‐level differences. Such geographic analysis can be used to discern which public policies and regional factors impact buprenorphine access.
Nano‐curcumin supplementation in patients with mild and moderate acute pancreatitis: A randomized, placebo‐controlled trial
Authors: Chegini Maedeh , Sadeghi Amir , Zaeri Farid , Zamani Majid , Hekmatdoost Azita 
Published: July 2023

AbstractWe aimed to investigate whether nano‐curcumin as an anti‐inflammatory agent is effective in patients with mild and moderate AP. This study was a double‐blind, parallel‐arm randomized controlled trial conducted at Taleghani hospital, Tehran, Iran. Eligible subjects with a diagnosis of mild and moderate AP were randomly assigned to receive either two doses of nano‐curcumin (40 mg) or placebo (control) daily for 2 weeks. The primary endpoint was gastrointestinal (GI) ward length of stay (LOS). A total of 42 patients were randomly assigned to receive either nano‐curcumin (n = 21) or placebo (n = 21). Compared with placebo, nano‐curcumin supplementation decreased hospital LOS (RR = 0.67, 95% CI: 0.502–0.894; p = 0.006), reduced the need for analgesics over time (OR = 0.576, 95% CI: 0.421–0.790; p = 0.001), and increased overall appetite score over the study period (β = 0.104, SE: 0.053; p = 0.049). No adverse effects or mortality were reported and there was no withdrawal during the study period. The results indicate that nano‐curcumin as an adjuvant therapy is safe and may reduce GI ward LOS, analgesics requirement, and improve the overall appetite in patients with mild and moderate AP. Future multi‐center trials with larger sample sizes are required to verify these findings. Clinical trial registration: www.ClinicalTrials.gov NCT04989166.
GNSS‐stereo‐inertial SLAM for arable farming
Authors: Cremona Javier , Civera Javier , Kofman Ernesto , Pire Taihú 
Published: July 2023

AbstractThe accelerating pace in the automation of agricultural tasks demands highly accurate and robust localization systems for field robots. Simultaneous Localization and Mapping (SLAM) methods inevitably accumulate drift on exploratory trajectories and primarily rely on place revisiting and loop closing to keep a bounded global localization error. Loop closure techniques are significantly challenging in agricultural fields, as the local visual appearance of different views is very similar and might change easily due to weather effects. A suitable alternative in practice is to employ global sensor positioning systems jointly with the rest of the robot sensors. In this paper we propose and implement the fusion of global navigation satellite system (GNSS), stereo views, and inertial measurements for localization purposes. Specifically, we incorporate, in a tightly coupled manner, GNSS measurements into the stereo‐inertial ORB‐SLAM3 pipeline. We thoroughly evaluate our implementation in the sequences of the Rosario data set, recorded by an autonomous robot in soybean fields, and our own in‐house data. Our data includes measurements from a conventional GNSS, rarely included in evaluations of state‐of‐the‐art approaches. We characterize the performance of GNSS‐stereo‐inertial SLAM in this application case, reporting pose error reductions between 10% and 30% compared to visual–inertial and loosely coupled GNSS‐stereo‐inertial baselines. In addition to such analysis, we also release the code of our implementation as open source.
(NH4)2(I5O12)(IO3) and K1.03(NH4)0.97(I5O12)(IO3): Mixed‐Valent Polyiodates with Unprecedented I5O12− Unit Exhibiting Strong Second‐Harmonic Generation Responses and Giant Birefringence
Authors: Ma Nan , Chen Jin , Li Bing‐Xuan , Hu Chun‐Li , Mao Jiang‐Gao 
Published: July 2023

AbstractSecond‐harmonic generation (SHG) response and birefringence are crucial properties for linear and nonlinear optical (NLO) materials, while it is difficult to further optimize these two key properties by using a single traditional functional building block (FBB) in one compound. Herein, a novel IO45− unit is identified, which possesses a square‐planar configuration and two stereochemically active lone‐pairs (SCALPs). By combining IO45− and IO3− units, the first examples of mixed‐valent polyiodates featuring an unprecedented bowl‐shaped I5O12− polymerized unit, namely (NH4)2(I5O12)(IO3) and K1.03(NH4)0.97(I5O12)(IO3), are successfully synthesized. Excitingly, both crystals exhibit strong SHG responses (16 × KDP and 19.5 × KDP @1064 nm) as well as giant birefringence (∆nexp = 0.431 and 0.405 @546 nm). Detailed structure‐property analyses reveal that the parallel aligned planar IO45− units induce the properly aligned high‐density SCALPs, leading to strong SHG response and giant birefringence for both materials. This work not only provides two new potential NLO and birefringent crystals, but also discovers a novel promising FBB (IO45−) for developing high‐performance linear and nonlinear optical materials.
A multi‐faceted analysis of the performance variability of virtual machines
Authors: Baresi Luciano , Dolci Tommaso , Quattrocchi Giovanni , Rasi Nicholas 
Published: July 2023

AbstractCloud computing and virtualization solutions allow one to rent the virtual machines (VMs) needed to run applications on a pay‐per‐use basis, but rented VMs do not offer any guarantee on their performance. Cloud platforms are known to be affected by performance variability, but a better understanding is still required. This article moves in that direction and presents an in‐depth, multi‐faceted study on the performance variability of VMs. Unlike previous studies, our assessment covers a wide range of factors: 16 VM types from 4 well‐known cloud providers, 10 benchmarks, and 28 different metrics. We present four new contributions. First, we introduce a new benchmark suite (VMBS) that let researchers and practitioners systematically collect a diverse set of performance data. Second, we present a new indicator, called VI, that allows for measuring variability in the performance of VMs. Third, we illustrate an analysis of the collected data across four different dimensions: resources, isolation, time, and cost. Fourth, we present multiple predictive models based on machine learning (ML) that aim to forecast future performance and detect time patterns. Our experiments provide important insights on the resource variability of VMs, highlighting differences and similarities between various cloud providers. To the best of our knowledge, this is the widest analysis ever conducted on the topic.
Green high‐performance thin layer chromatography‐densitometric approach for tablet formulation containing remogliflozin etabonate and vildagliptin
Authors: Patel Khushbu , Kotadiya Rajendra 
Published: July 2023

AbstractA new high‐performance thin‐layer chromatography (HPTLC) method has been developed to analyze Vildagliptin (VLD) and Remogliflozin etabonate (RE) tablets. The procedure uses a mobile phase of methanol, ethyl acetate, toluene, and ammonia (1.5:7:1:0.5, by volume), a stationary phase of silica gel 60 F254 precoated TLC plates, and densitometry to gauge the amount of drug present. The method's linearity, accuracy, precision, and robustness were carefully evaluated. VLD and RE had Rf values of 0.46 and 0.64, respectively, with R2 values of 0.997, indicating good linearity over 10,000–50,000 ng/band for RE and 5000–25,000 ng/band for vildagliptin. Studies on forced deterioration were carried out to assess the probable degradation process. The resolution in the Rf values between the degradant and drug peaks was good. The study revealed that the drug was sensitive to hydrolysis and oxidative stress degradation and was transformed into the active Remogliflozin after the forced degradation tests. The Remogliflozin and RE bands were easily distinguishable. This method can be utilized for analyzing not only the tablet formulation of the drug but also stability samples and standard quality control samples. The Analytical Greenness Calculator methodology aided the greenness evaluation of the method.
Seismic responses of high‐rise structure under multiple‐component ground motions
Authors: Wei Wenhui , Hu Ying , Pi Yong‐Lin 
Published: July 2023

SummaryIn this paper, we studied the responses of high‐rise structures under the multiple‐component ground motions, such as horizontal; coupled horizontal and rocking; and coupled horizontal, vertical, and rocking ground motion. First, the principle and process of obtaining the rotation component by using wavelet analysis are explained, and the rocking ground motion was obtained by wavelet analysis from translational ground motions. The correctness of this method was verified by shaking table tests. Next, the shaking table tests were performed on the scale model of a high‐rise TV tower under the horizontal, multiple ground motions. Under multiple ground motions, the amplitudes of the displacement and the acceleration increased to a certain extent, and the increased range of the acceleration was relatively larger. In addition, the displacement time‐history curve with the rocking ground motion showed an asymmetric offset. Subsequently, the dynamic equation of a high‐rise structure under the multiple ground motions was established, and the additional second‐order effect of the rocking ground motion was also considered. The results of the dynamic equation were well consistent with the shaking table test results, which verified the rationality and the accuracy of the dynamic equation. Besides, the result from the theoretical calculation and test indicated that the additional second‐order effect with the rocking ground motion that led to the ground tilting should not be ignored. In the last part, the elastic–plastic properties of the structure under the horizontal and rocking ground motion in the rare earthquake were analyzed. The displacement of the structure with the rocking ground motion increased significantly at the elastic–plastic stage, and the asymmetry deviation degree of the displacement and restoring force–displacement trend of the structure were more significant, which would impact the dynamic stability of the structure and even increase the possibility of structural collapse.
The curative effect of ozonated bidistilled water on Escherichia coli‐induced endometritis in rats
Authors: Kocamüftüoğlu Mesih , Bozkurt Gökhan , Ağaoğlu Ali Reha , Özmen Özlem , Öztürk Dilek 
Published: July 2023

AbstractBackgroundEndometritis is a prevalent and challenging condition that affects livestock, and its effective treatment is the use of intrauterine antibiotics. Antibiotic use may lead to negative consequences, including residue in tissues and the emergence of antibiotic resistance.ObjectivesThe aim of this study was to assess the therapeutic potential of ozonated bidistilled water in the treatment of Escherichia coli‐induced endometritis in rat models, comparing it to conventional antibiotic treatment.MethodsA total of 21 female Wistar Albino rats were used for this study. E. coli from the uterus of cows with endometritis at a concentration of 1.0 × 109 cfu/mL inoculated into rat uteruses. After inoculation, it was confirmed macroscopically that experimental endometritis was induced in all individuals. And, the rats with endometritis were randomly divided into three groups treated with intrauterine bidistilled water enriched with ozone, antibiotics and 0.9% NaCl. The uterine tissues were examined histopathologically.ResultsIn the semiquantitative analyses, significantly lower histopathological scores were observed for both the bidistilled water enriched with ozone and antibiotic‐treated endometritis groups compared to the control group (p < 0.05).ConclusionsOzone‐enriched bidistilled water can be used in the treatment of experimentally induced endometritis in rats, and can provide effective microbiological and histopathological improvement. Further studies involving larger populations of different species are needed to determine the medical suitability of this new treatment.
A modified tenectomy approach to a case of spastic paresis in a 10‐month‐old bullock
Authors: McFarland David Samuel , Woods Tom Samuel , Macrae Alastair Ian , Kelly Rob Francis 
Published: July 2023

AbstractAlthough treatment of bovine spastic paresis cases is often performed using a tibial neurectomy, the potential for substantial economic loss in an older animal, cost of anaesthesia and heightened difficulty of the procedure can preclude its use in veterinary practice. This report describes a tenectomy performed on a 450 kg bullock that presented with spastic paresis of the left hindlimb. Tenectomy of the medial and lateral tendons of the gastrocnemius muscle provided a good surgical treatment option through a modified incision site in a cranio‐lateral approach. Tenectomy has the advantages of being less invasive than neurectomy, with clearly identifiable landmarks. A key aspect in achieving a successful outcome is to preserve the superficial digital flexor tendon. In the experience of the authors, when compared to tibial neurectomy in similar sized animals, tenectomy had a reduced surgical time and minimised potential complications such as dropping of the hock.
Computer-Aided Diagnosis and Prediction in Brain Disorders
Authors: Venkatraghavan Vikram , Voort Sebastian R. van der , Bos Daniel , Smits Marion , Barkhof Frederik , Niessen Wiro J. , Klein Stefan , Bron Esther E. 
Published: July 2023

AbstractComputer-aided methods have shown added value for diagnosing and predicting brain disorders and can thus support decision making in clinical care and treatment planning. This chapter will provide insight into the type of methods, their working, their input data –such as cognitive tests, imaging, and genetic data– and the types of output they provide. We will focus on specific use cases for diagnosis, i.e., estimating the current “condition” of the patient, such as early detection and diagnosis of dementia, differential diagnosis of brain tumors, and decision making in stroke. Regarding prediction, i.e., estimation of the future “condition” of the patient, we will zoom in on use cases such as predicting the disease course in multiple sclerosis and predicting patient outcomes after treatment in brain cancer. Furthermore, based on these use cases, we will assess the current state-of-the-art methodology and highlight current efforts on benchmarking of these methods and the importance of open science therein. Finally, we assess the current clinical impact of computer-aided methods and discuss the required next steps to increase clinical impact.
Integration of Multimodal Data
Authors: Lorenzi Marco , Deprez Marie , Balelli Irene , Aguila Ana L. , Altmann Andre 
Published: July 2023

AbstractThis chapter focuses on the joint modeling of heterogeneous information, such as imaging, clinical, and biological data. This kind of problem requires to generalize classical uni- and multivariate association models to account for complex data structure and interactions, as well as high data dimensionality.Typical approaches are essentially based on the identification of latent modes of maximal statistical association between different sets of features and ultimately allow to identify joint patterns of variations between different data modalities, as well as to predict a target modality conditioned on the available ones. This rationale can be extended to account for several data modalities jointly, to define multi-view, or multi-channel, representation of multiple modalities. This chapter covers both classical approaches such as partial least squares (PLS) and canonical correlation analysis (CCA), along with most recent advances based on multi-channel variational autoencoders. Specific attention is here devoted to the problem of interpretability and generalization of such high-dimensional models. These methods are illustrated in different medical imaging applications, and in the joint analysis of imaging and non-imaging information, such as -omics or clinical data.
Resümee
Authors: Künnemann Andreas 
Published: July 2023

ZusammenfassungDieses Kapitel fasst die wesentlichen Ergebnisse und Methoden der vorliegenden Arbeit zusammen und ordnet diese ein. So bleibt festzuhalten, dass eine umfassende, in sich geschlossene und gut nachvollziehbare Darstellung der Existenz- und Regularitätstheorie zweidimensionaler Variationsprobleme erreicht wird, die auf Randwertprobleme partieller Differentialgleichungssysteme, insbesondere auf das Plateausche Problem für Flächen vorgeschriebener mittlerer Krümmung, angewendet werden kann.
Impact of Innovative Practices Adopted in the Dental Preclinical Labs Post COVID-19 on Student Performance Based on Skills and Knowledge
Authors: Narasimhan Sangeetha , Al-Daghestani Hiba Saad , Al Kawas Sausan 
Published: July 2023

AbstractThe coronavirus-induced disease (COVID-19) was declared a pandemic by the World Health Organization (WHO) on the March 11, 2020. This Pandemic has resulted in the largest disruption of the education sector across the globe. Alternatively, this crisis has also induced path-breaking reforms to the global education system in the recent past. With evolving technology, online teaching has become the most convenient mode for lectures and discussions. This acute transformation caused a challenging environment to conduct laboratory sessions for students by adhering to social distancing. Alternatively, delivering the preclinical dental laboratory exercises through online mode was the only available option globally. This paper enlightens a few of the innovative techniques employed in conducting online preclinical dental laboratory sessions for the Bachelor of Dental Surgery (BDS) students in the College of Dental Medicine at University of Sharjah. The study aimed at comparing the student performance in the dental preclinical labs evaluated based on skills and knowledge before and after the introduction of the innovative practices by online mode. The results of the study showed that the BDS1 students’ overall performance in the preclinical labs after adopting innovative practices was higher (p = 0.000) compared to the original practice of onsite delivery of labs. Students displayed enhanced tooth-carving skills (p = 0.000) with the introduction of online monitoring of tooth morphology labs. Moreover, BDS2 student performance in dental histology and anatomy labs did not show any significant improvement through the online mode of teaching (p = 0.01). Although COVID-19 hit the world abruptly, it helped in creating digital innovative solutions, thereby easing the teaching and learning process in dental education.