bluuebunny/crossref_metadata_2025_split huggingface dataset:
Construction of a nomogram for preoperative prediction of the risk of lymph node metastasis in early gastric cancer
Authors: Liu Zitao , Tian Huakai , Huang Yongshan , Liu Yu , Zou Feilong , Huang Chao 
Published: January 2023

BackgroundThe status of lymph node metastasis (LNM) in patients with early gastric cancer (EGC) is particularly important for the formulation of clinical treatment. The purpose of this study was to construct a nomogram to predict the risk of LNM in EGC before operation.MethodsUnivariate analysis and logistic regression analysis were used to determine the independent risk factors for LNM. The independent risk factors were included in the nomogram, and the prediction accuracy, discriminant ability and clinical practicability of the nomogram were evaluated by the receiver operating characteristic curve (ROC), calibration curve and clinical decision curve (DCA), and 100 times ten-fold cross-validation was used for internal validation.Results33 (11.3%) cases of AGC were pathologically confirmed as LNM. In multivariate analysis, T stage, presence of enlarged lymph nodes on CT examination, carbohydrate antigen 199 (CA199), undifferentiated histological type and systemic inflammatory response index (SIRI) were risk factors for LNM. The area under the ROC curve of the nomogram was 0.86, the average area under the ROC curve of the 100-fold ten-fold cross-validation was 0.85, and the P value of the Hosmer-Lemeshow test was 0.60. In addition, the clinical decision curve, net reclassification index (NRI) and Integrated Discriminant Improvement Index (IDI) showed that the nomogram had good clinical utility.ConclusionsWe found that SIRI is a novel biomarker for preoperative prediction of LNM in EGC, and constructed a nomogram for preoperative prediction of the risk of LNM in EGC, which is helpful for the formulation of the clinical treatment strategies.
Prognostic impact of tumor size on isolated hepatocellular carcinoma without vascular invasion may have age variance
Authors: Zhang Yi , Zhang Jun-Gang , Yu Wei , Liang Lei , Wu Chun , Zhang Cheng-Wu , Xie Ya-Ming , Huang Dong-Sheng , Shi Ying 
Published: January 2023

BackgroundPrevious studies suggested that tumor size was an independent risk factor of prognosis for hepatocellular carcinoma (HCC). However, the general prognostic analysis did not consider the interaction between variables. The purpose of this study was to investigate whether the effect of tumor size on the prognosis of isolated HCC without vascular invasion varies according to covariates.MethodsPatients were selected from the Surveillance, Epidemiology, and End Results (SEER) database to investigate whether there was an interaction between age and tumor size on the prognosis. Then the trend test and the value of per 1 SD of tumor size were calculated. In addition, the data of Zhejiang Provincial People's Hospital meeting the requirements were selected to verify the obtained conclusions.ResultsMultivariable Cox regression analysis of the database cohort showed that age, gender, tumor size, pathological grade and marital status were independent risk factors for prognosis. Interaction test showed that there was an interaction between age and tumor size (P for interaction &lt; 0.05). Stratified analysis by age showed that tumor size was an independent risk factor for prognosis when age ≤65 years old (HR:1.010,95%CI1.007–1.013 P &lt; 0.001), while tumor size was not an independent risk factor for prognosis when age &gt;65 years old. This result was confirmed by trend analysis (P for trend &lt; 0.001), and the prognostic risk increased by 42.1% for each standard deviation increase of tumor size among patients age ≤65 years. Consistent conclusion was obtained by multivariable cox regression analysis and interaction test on the verification cohort. In the validation cohort, for each standard deviation increase of tumor size in patients ≤65 years old, the risk of prognosis increased by 52.4%.ConclusionTumor size is not an independent risk factor for the prognosis of isolated HCC without vascular invasion when patient's age &gt;65 years. Therefore, when analyzing the relationship between tumor size and prognosis, stratified analysis should be performed according to age.
Analysis of the effect of phloroglucinol on pregnancy outcomes involving frozen embryo transfers in patients with endometriosis: A retrospective case-control study
Authors: Pang Wen-Juan , Feng Xu , Wang Xiang , Wang Liang , Sun Ning-Xia 
Published: January 2023

ObjectiveAbnormal contraction of uterus and vascular smooth muscle lead to the formation of hypoxia environment in uterus. Abnormal contraction may be the basis of dysmenorrhea, endometriosis, infertility and other diseases. Phloroglucinol is a non-atropine and non-papaverine smooth muscle spasmolytic agent, which can reduce the abnormal contraction of uterine smooth muscle. This study investigated the effect of phloroglucinol on frozen embryo transfer in patients with endometriosis.MethodsThe data of patients with endometriosis who underwent a frozen embryo transfer in Shanghai Changzheng Hospital from August 2018 to August 2021, comprising a total of 453 cycles, were retrospectively analyzed. The patients for whom phloroglucinol was included over 217 cycles were administered intramuscully 40 mg phloroglucinol starting on the day of progesterone administration, then once daily up to day 7 after the embryo transfer. Those for whom phloroglucinol was not administered over 236 cycles were used as the control group. The age of 35 years was used as a boundary in this study to observe the pregnancy outcomes of patients in the two different age groups.ResultsThe biochemical pregnancy rate (63.13% vs. 51.27%), embryo implantation rate (44.64% vs. 33.60%), clinical pregnancy rate (59.64% vs. 48.30%), and live birth rate (52.99% vs. 36.86%) after the administration of phloroglucinol were higher than for patients in the control group, and the early abortion rate (7.75% vs. 20.18%) was also lower. The differences were statistically significant (P &lt; 0.05). In particular, in the age group &lt;35 years old, the embryo implantation rate (51.81% vs. 39.38%), clinical pregnancy rate (69.34% vs. 57.55%), and the live birth rate (63.50% vs. 44.60%) after phloroglucinol intervention rose significantly, and the abortion rate dropped (6.32% vs. 17.5%), indicating a statistically significant difference (P &lt; 0.05). However, pregnancy outcomes showed no difference in the age group ≥35 years old (P &gt; 0.05).ConclusionContinuous low-dose phloroglucinol pretreatment before and after frozen embryo transfer can improve both the clinical pregnancy and live birth rates and reduce the risk of abortion in younger infertile patients with endometriosis.
Optimalisasi Pemanfaatan Digital Marketing untuk UMKM (Usaha Mikro, Kecil dan Menengah)
Authors: Bangun Cicilia Sriliasta , Purnama Suryari 
Published: January 2023

Merebaknya pandemic Covid-19 tidak dipungkiri telah memaksa masyarakat untuk memanfaatkan kemajuan teknologi dalam kehidupan sehari-hari. Pengguna internet di Indonesia meningkat pesat, dan hal ini harusnya menjadi peluang yang dapat dimanfaatkan oleh pelaku UMKM yang saat pandemik sangat terpuruk. Sayangnya masih banyak pelaku UMKM yang belum menggunakan digital marketing dalam memasarkan produknya. Ada berbagai jenis digital marketing yang dapat dimanfaatkan oleh pelaku UMKM, antara lain: konten marketing, social media marketing, Search Engine Optimization (SEO), Search Engine Marketing (SEM), Pay-Per-Click (PPC), email marketing dan pesan singkat (instant messaging). Tiap jenis digital marketing tentu memiliki karakter pengguna yang berbeda yang harus dipahami oleh pelaku UMKM. Pelatihan yang dihadiri oleh 30 pelaku UMKM ini juga memberikan penjelasan langkah sederhana dalam memanfaatkan digital marketing, yaitu: mengenali produk yang dipasarkan dengan baik, mengenali target pasarnya, mengenali pesaing, menyiapkan konten marketing, mendistribusikan konten marketing tersebut sesuai dengan jenis yang dipilih, mengevaluasi konten untuk menguatkannya, menjadwalkan distribusi konten dan menentukan targetnya, dan yang paling penting adalah konsisten dan tetap mengikuti perkembangan pasar. Pemahaman yang baik membuat para pelaku UMKM mampu memanfaatkan digital marketing untuk meningkatkan omzet penjualannya.
ANALISIS NILAI TAMBAH RUMPUT LAUT SEBAGAI PRODUK PANGAN PADA KELOMPOK USAHA “ARES” KOTA MATARAM
Authors: ARTIKA IDA BAGUS EKA , MARINI IDA AYU KETUT , KENCANA A. A. MADE SURYA , NOPIARI IDA AYU , ARIFFIANTI INDAH 
Published: January 2023

Processing raw materials into a product with higher value added is a positive endeavor, to provide higher benefits for the welfare of society. Seaweed as one of the mainstay commodities in the West Nusa Tenggara region will provide high benefits if it is successfully processed into products with a higher selling value than if it is sold as a ra product. This study aims to determine the value added of processed food products made from seaweed, namely seaweed rengginang, seaweed kripik and seaweed crackers which are processed by the "ARES" Business Group in Karangbaru Village, Mataram City. The research method is descriptive, and value added analysis is based on the Hayami Method. From the calculated of value added , it turns out that the value added of seaweed kripik produces the highest value added, which is Rp. 111,400,- per kilogram of processed seaweed, then the value added of seaweed crackers is Rp. 98.000, - and the added value of seaweed rengginang is Rp. 78,050,- Furthermore, it is suggested to the “ARES” Business Group if the demand for seaweed kripik is relatively good, the production of seaweed kripik needs to be increased in capacity in the future, and the “ARES” Business Group to continue to be creative in making products made from seaweed to be processed into superior products, as an effort to increase the value added of raw materials into products with higher value added
ADOPSI TEKNOLOGI BUDIDAYA TANAMAN KEDELAI DI TINGKAT PETANI KABUPATEN LOMBOK BARAT
Authors: WEDASTRA MADE SUMA , SUARTHA I DEWA GEDE , ADNYANA I PUTU CAKRA PUTRA 
Published: January 2023

Soybean is one of the horticultural crops developed in Indonesia, because of its benefits, besides being able to be consumed directly, it can also be used as raw material for home industries and large industries such as tempeh, tofu, soy sauce, soy milk and others. The various benefits of soybeans are not supported by sufficient availability, so that until now Indonesia is still exporting soybeans. This study aims to determine the soybean cultivation system implemented by farmers in West Lombok Regency. This research is a descriptive study, which was carried out in Gerung Village, Gerung District and Kediri Village, Kediri District, West Lombok Regency. Determination of the location in a stratified (two-stage) selection mechanism, is first to choose the sub-district with the largest soybean planting area, then from the selected sub-district the village with the largest soybean planting area is also determined. The number of respondents who were taken was done by non-random sampling, each village was 30 respondents, so that the total number of respondents was 60 people. The data used in this study are qualitative data and quantitative data, with data collection techniques using interviews, observations and documentation, and data collection tools using questionnaires.The results of the study indicate that the farming system adopted by the respondent farmers has not been fully implemented in accordance with the recommendations. This is related to the different socio-economic conditions of farmers.
SARANA PENDIDIKAN, KESEHATAN DAN TINGKAT KEMISKINAN DI KECAMATAN TANJUNG SEBAGAI PUSAT PERTUMBUHAN KABUPATEN LOMBOK UTARA, PASKA GEMPA 2018 DAN MASA PANDEMI COVID-19
Authors: ALWI MUHAMMAD , KARISMAWAN PUTU , YUDHA S I DEWA KETUT , HARSONO IWAN 
Published: January 2023

Earthquake 2018 and than Covid-19 Pandemic as starting point to conduct research about condition of educations, healties and rate of poverty in Tanjung Districts, North Lombok, West Nusa Tenggara Province. Base on analysis data of centre of Statistic Bureau of North Lombok (BPS) and population projection of Tanjung districts untill 2025, the condition are: fasilities of kindergarten has not been enough yet. The distibution of that finfrastructure among the vilages is not equal. The elemnteray or primary school (Sekolah Dasar), junior high school ( Sekolah Menengah Pertama) are more than enough, Midle high school (sekolah Menengah Atas) are not enough yet. The aditional education fasilities in 2022 need to add, such as 20 units of new kindergarten, 1 units of Midle high school. Health fasilities relatively has not been enough yet, compare to district Tanjung population as much 220.412 and the position distric Tanjung as capital of North Lombok regency e.g community helath centre and sub community health centre (Puskesmas dan Puskesmas Pembantu), polyclinic and laboratory, hospital, private doctor services, farmacy are not enough yet realtively to population. It should there 5 unit of Community health centre dan 82 sub cummunity helath centre, 10 private doctor services, 1 unit of laboratory, 3 unit of hospital C or 1 B type. Base on qualitative data that rate of poverty in Tanjung district is relativly high. The lowest education level, skill, Lack of employment opurtunity, and capital are the prime faktor of poverty
PELATIHAN STRATEGI BRANDING PADA SMKS TINTA EMAS INDONESIA DENGAN WEBSITE DAN SOSIAL MEDIA
Authors: Osly Prima Jiwa , Araswati Fulki Dwiyandi , Meutia Wita , Ihsani Irfan 
Published: January 2023

Kegiatan pengabdian ini dilatar belakangi dengan keadaan pandemi menuntut perubahan yang amat cepat dan signifikan di berbagai bidang termasuk Pendidikan, serta persaingan global di dunia pendidikan pada era modern menunjukkan kedinamisan sektor pendidikan. Menghadapi persaingan global sekolah harus jeli dalam melihat peluang yang ada di masyarakat dengan cara memiliki citra merek (brand image) yang baik di mata masyarakat Tujuan dari kegiatan pengabdian ini adalah melakukan realisasi terhadap pelatihan branding sekolah kepada guru dan manajemen sekolah menggunakan teknologi informasi secara maksimal khususnya dengan website dan sosial media. Hasil dari pelaksanaan kegiatan pengabdian telah berjalan dengan baik dan lancar. Secara terperinci kegiatan ini dinilai bermanfaat oleh para peserta, guru-guru SMK Tinta Emas Indonesia telah termotivasi untuk melakukan promosi sekolah serta memahami strategi branding sekolah dengan menggunakan website dan sosial media.
ANALISIS KEBIJAKAN DEVIDEN SEBELUM DAN SESUDAH UU OMNIBUS LAW CIPTA KERJA DIBERLAKUKAN DI ERA NEW NORMAL
Authors: Damayanti Ameilia 
Published: January 2023

Penelitian ini bertujuan untuk mengetahui ada perbedaan kebijakan deviden sebelum dan sesudah UU Omnibus Law Cipta Kerja diberlakukan di era new normal. Variabel yang digunakan dalam penelitian ini adalah kebijakan deviden yang diukur melalui dividen payout ratio. Sampel yang digunakan dalam penelitian ini adalah perusahaan industry farmasi dan makanan & minuman yang terdaftar di Bursa Efek Indonesia, menerbitkan laporan keuangan pada tahun 2017 – 2020 dengan 19 perusahaan sampel yang menggunakan metode purposive sampling. Hasil penelitian menunjukkan bahwa ada perbedaan kebijakan deviden pada industry farmasi, makanan dan minuman di masa sebelum new normal atau sebelum ketentuan UU Cipta Kerja Omnibus Law diberlakukan di Indonesia yakni pembayaran atau kebijakan deviden lebih rendah. Lalu ada perbedaan kebijakan deviden pada industry farmasi, makanan dan minuman di masa sesudah new normal atau sesudah ketentuan UU Cipta Kerja Omnibus Law diberlakukan di Indonesia yakni pembayaran atau kebijakan deviden lebih tinggi.
DIVERSIFIKASI PAKET STAYCATION HOTEL KAWASAN TUBAN, KABUPATEN BADUNG, BALI DI MASA PANDEMI COVID-19
Authors: Lumanauw Nelsye , Gst. Bgs. Wirya Gupta  
Published: January 2023

Industri perhotelan memanfaatkan situasi pandemi Covid-19 dengan menciptakan paket staycation untuk mempertahankan bisnis. Kebijakan pembatasan karyawan dan fasilitas yang dibuka mengakibatkan ketidaksesuaian antara upaya diversifikasi produk dengan kondisi hotel sebenarnya dan harapan wisatawan melakukan kegiatan staycation. Analisis terhadap diversifikasi paket staycation hotel kawasan Tuban, Badung, Bali dan pelaksanaannya merupakan tujuan penelitian ini. Metode penelitian analisis deskriptif kualitatif digunakan terhadap penelitian ini untuk menganalisis paket staycation hotel kawasan Tuban, Badung, Bali yang menjadi obyek penelitian ini, yaitu The Patra Bali Resort & Villas, Rama Beach Resort & Villas, Quest Hotel Kuta by Aston, Hotel Sulis Beach & Spa. Teori Resources Based View digunakan untuk menganalisis produk-produk unggulan hotel yang dikemas menjadi paket staycation. Teori diversifikasi digunakan untuk menganalisis pelaksanaan paket staycation di hotel, ditunjang dengan review wisatawan baik secara online maupun offline. Kesimpulan penelitian ini adalah tren staycation di tengah pandemi Covid-19 menunjukan pergeseran pola berwisata oleh masyarakat. Hotel harus berupaya mengoptimalkan karyawan yang ada, sehingga brand image hotel tetap baik.
Kata kunci: diversifikasi produk, staycation, pandemi Covid-19
PENGELOLAAN POTENSI DESA WISATA RUMADIAN KECAMATAN MANYEUW MELALUI KEBERLANJUTAN
Authors: Arianto Kerubun  , Renjaan Melissa , Marselus Hungan  
Published: January 2023

Pada tahun 2020 dinas pariwisata Kabupaten Maluku Tenggara membentuk 25 desa wisataa. Pengembangan Desa wisataa didukung adanya potensi alam, sosial, budaya, sejarah dan lainnya. Salah satu desa yang potensial dan telah dikembangkan menjadi desa wisata adalah Desa Rumadian. Desa Rumadian memiliki potensi hutan mangrove yang masih alami, pertanian beras merah, sumber mata air, wisata buatan, kekhasan budaya dan tradisi serta potensi wisata sejarah yang mana dapat menarik wisatawan untuk berkunjung. Guna meningkatkan pariwisata Desa Rumadian melalui potensi-potensi yang dimiliki, maka dibutuhkan suatu konsep pengelolaan potensi desa wisata yang merujuk pada aspek pengelolaan sumber daya pariwisata, pengelolaan sumber daya manusia, pengelolaan pemasaran, dan manajemen resiko. Tujuan penelitian adalah menganalisis pengelolaan desa wisataa dan untuk menyusun konsep pengelolaan potensi desa wisataa Rumadian, Kec. Manyeuw. Metode penelitian yang digunakan adalah Kualitatif. Analisis Data menggunakan analisis deskriptif kualitatif. Hasil pada penelitian ini menunjukan bahwa pengelolaan setiap potensi desa wisata belum optimal dalam pengelolaan sumber daya pariwisata alam dan budaya, pengelolaan sumber daya manusia, pengelolaan sumber daya pariwisata serta belum memiliki manajemen resiko. Selanjutnya, pada penelitian ini menghasilkan suatu konsep pendekatan pengelolaan desa wisataa Rumadian yang berisi point-point penting dalam menghubungkan aspek pengelolaan sumberdaya pariwisata, pengelolaan sumberdaya manusianya, pengelolaan pemasaran dan manajemen resiko dengan potensi desa
DEVELOPMENT OF LAMBANOG (COCONUT VODKA) BASED CONCOCTION AS AUTHENTIC COCKTAIL DRINK IN THE PROVINCE OF THE PHILIPPINES
Authors: Ana Luna E. Bonina  , Herrera Maricel 
Published: January 2023

The purpose of the study is to develop Quezon’s authentic cocktail drink to promote the local product in Quezon Province using lambanog based and local ingredients in selected municipalities of 1st and 2nd districts in Quezon province specifically Mauban, Pagbilao, Sampaloc, Tayabas, Infanta, Sariaya and Lucena City. This is a Research and Development type of study which focuses on developing products that would contribute to the industry of the province. Owners, managers, and bartenders were the respondents of the study.

The methodology used in the study was Research and Development using a developed lambanog based concoction focused on three phases; generating phase where all ingredients/materials for the development of local lambanog concoction were gathered, followed by the development phase where the concoction according to the acceptance of the taste and physical attributes of the lambanog cocktail were created and developed and lastly is the field try-out phase where the acceptability of the lambanog based concoction to the market were tested. As to the result of the study, among the varieties of the different types of ingredients in Quezon province gathered by the researchers as modifiers, the tanglad, butterfly dried ternate, bignay, mulberry fruit, katmon, liputi, and passion fruit were proven to have a good blend with the lambanog concoction when it comes to its appearance, taste/flavor, and odor/smell. Among the three cocktail drinks Cocktail 2 with concoction of lambanog, bignay, mulberry fruit, katmon, liputi and simple syrup got the highest acceptance level when it comes to its appearance. While to its taste/flavor and smell/odor cocktail 1 with the concoction of lambanog, buko, tanglad, and butterfly dried ternate got the highest acceptance level.

For the study to be more beneficial to the community as well as the lambanog and hospitality industry, further study is recommended which will focus on the marketability of the lambanog cocktails to be participated by the business establishment owners, staff and customers.
DEVELOPMENT STRATEGY OF MUSIC TOURISM : UBUD VILLAGE JAZZ FESTIVAL AS COMMUNITY-BASED EVENT IN UBUD, BALI
Authors: Puspita Nungky 
Published: January 2023

Music Tourism is the specialization interest in tourism and this tourism increasing the tourist enthusiasm and attraction. This study describe the Ubud Village Jazz Festival which is the one of the International Music festival that held on Ubud, Bali and also the community-based international music festival . For the analysis, this study use SWOT analyses to make the strategy and the recommendation and also use Elements of Jazz Music Festival theory according to Racapong Khaiewpan. This study use the data from observation and literature study. This research focuses on music tourism attractions and local participation that collaborated in this special event. The results of this study are Ubud Village Jazz Music Festival fulfill the four elements of Jazz Music Festival, for the element of Music Tourism Management in Administrative Aspect this event have so many sponsorships with The Indonesian Creative Economy Agency (BEKRAF), Local brand and business and also with the local people to contributed. For the Music Tourism Management in Design Aspect, this event used Eco-friendly materials. For Marketing Aspect, Ubud Village Festival have sponsorhip with the local TV station to promoting the event. For the Operational Aspect, this event have the schedule and the rules. For Management in Risk Aspect this event have the preparation to discrease the risk for the uncertain weather. The management also advised the tourist to have some preparation to bring raincoat and umbrella because this event is an outdoor event. The local people involved in the whole aspect including the stage of planning, implementation, benefit receipt, monitoring and evaluation which they have done well and organized.
Keyword: special event, music tourism, community participation, SWOT analyses