bluuebunny/crossref_metadata_2025_split huggingface dataset:
Research on workspace visual-based continuous switching sliding mode control for cable-driven parallel robots
Authors: Qian Sen , Zhao Zeyao , Qian Pengfei , Wang Zhengyu , Zi Bin 
Published: September 2023

AbstractAchieving the high-precision control of cable-driven parallel robots (CDPRs) is complex because of their structural properties. In this paper, a quintessential redundant CDPR is designed as the research subject, and a continuous switching sliding mode controller based on workspace vision is implemented to enhance the accuracy and stability of trajectory tracking. In addition, a virtual prototype of the CDPR with uncertainties is created in the simulation analysis software ADAMS, and co-simulation is performed with the control system designed in Simulink to validate the effectiveness of the proposed control strategy. Furthermore, a CDPR platform is established for trajectory tracking experiments using the visual-based position feedback method. The trajectory tracking performance with the three control schemes is then evaluated. The experimental results show that the continuous switching sliding mode control algorithm can significantly decrease trajectory tracking errors and exhibit superior trajectory tracking performance compared to the other control strategies.
Generalised solution to a 2D parabolic-parabolic chemotaxis system for urban crime: Global existence and large-time behaviour
Authors: Li Bin , Xie Li 
Published: September 2023

AbstractWe consider a parabolic-parabolic chemotaxis system with singular chemotactic sensitivity and source functions, which is originally introduced by Short et al to model the spatio-temporal behaviour of urban criminal activities with the particular value of the chemotactic sensitivity parameter
$\chi =2$
. The available analytical findings for this urban crime model including
$\chi =2$
are restricted either to one-dimensional setting, or to initial data and source functions with appropriate smallness, or to initial data and source functions with some radial symmetry. In the present work, our first result asserts that for any
$\chi \gt 0$
the initial-boundary value problem of this urban crime model possesses a global generalised solution in the two-dimensional setting, without imposing any small or radial conditions on initial data and source functions. Our second result presents the asymptotic behaviour of such solution, under some additional assumptions on source functions.
Serum anti-Müllerian hormone concentrations are related to embryo development: lessons from time-lapse imaging
Authors: Setti Amanda Souza , Braga Daniela Paes de Almeida Ferreira , Guilherme Patricia , Iaconelli Assumpto , Borges Edson 
Published: September 2023

SummaryOur objective was to study whether serum anti-Müllerian hormone (AMH) concentrations were associated with embryo morphokinetic events. This retrospective cohort study was performed in a private university-affiliated in vitro fertilization centre between March 2019 and December 2020 and included 902 oocytes cultured in a time-lapse imaging incubator, obtained from 114 intracytoplasmic sperm injection cycles performed. The relationship between AMH concentrations and morphokinetic events was investigated by considering the clustering of data (multiple embryos/patient). Evaluated kinetic markers were time to pronuclei appearance (tPNa) and fading (tPNf), time to two (t2), three (t3), four (t4), five (t5), six (t6), seven (t7), and eight cells (t8), (tSB) and time to the start of blastulation (tSB) and to blastulation (tB). Significant inverse relationships were observed between serum AMH concentrations and tPNf, t3, t4, t5, t6, t7, t8, and tB. The AMH was positively correlated with the KIDScore and implantation rate. Increased serum AMH concentrations correlated with faster embryo development. The clinical implications of this effect on embryo development warrant further investigation.
Homeownership rates, housing policies, and co-residence decisions
Authors: Grevenbrock Nils , Ludwig Alexander , Siassi Nawid 
Published: September 2023

AbstractHomeownership rates differ widely across European countries. We document that part of this variation is driven by differences in the fraction of adults co-residing with their parents. Comparing Germany and Italy, we show that in contrast to homeownership rates per household, homeownership rates per individual are very similar during the first part of the life cycle. To understand these patterns, we build an overlapping-generations model where individuals face uninsurable income risk and make consumption-saving and housing tenure decisions. We embed an explicit intergenerational link between children and parents to capture the three-way trade-off between owning, renting, and co-residing. Calibrating the model to Germany we explore the role of income profiles, housing policies, and the taste for independence and show that a combination of these factors goes a long way in explaining the differential life-cycle patterns of living arrangements between the two countries.
Land-price dynamics and macroeconomic fluctuations with general household preferences
Authors: Chen Been-Lon , Lai Zheng-Ze , Liao Shian-Yu 
Published: September 2023

AbstractThrough the collateral channel for entrepreneurs, a positive housing demand shock in Liu et al. [(2013) Econometrica 81, 1147–1184.] increases land prices and business investment, but consumption decreases on impact and there is thus a comovement problem. This paper improves Liu et al. [(2013) Econometrica 81, 1147–1184.] by adding general household preferences with broader intratemporal and intertemporal substitutions Bayesian estimation of our structural model based on aggregate US data suggests that the intratemporal substitution is larger than unity and the intertemporal substitution is smaller than unity. Our impulse responses show that a positive housing demand shock increases land prices, business investment, and consumption, which resolves the comovement problem. Moreover, the strength of the collateral channel linking land prices and business investment in our Bayesian DSGE model is larger than that in Liu et al. [(2013) Econometrica 81, 1147–1184.]. Housing demand shocks explain 39−43% of the variance of output and 41−47% of the variance of investment in our model, but the same shocks explain only 17−31% of the variance of output and 30−41% of the variance of investment in Liu et al. [(2013) Econometrica 81, 1147–1184.]. Variance decomposition reveals that housing demand shocks account for a larger share of the fluctuations in land prices, investment, employment, and output than other shocks. Using the marginal data density as the measure of fit for models, we find that our model can better explain the same US aggregate data.
The extent and nature of children’s involvement in food practice research: a scoping review of qualitative studies
Authors: Wright-Pedersen Sophie , Vidgen Helen , Abigail Badejo Foluke , Gallegos Danielle 
Published: September 2023

AbstractObjective:Aligning with the United Nations Convention on the Rights of the Child, amplification of children’s voice in food practice research aims to inform initiatives that cater to children’s needs and thus improve nutritional outcomes. The aim of this study was to describe children’s (aged 6–11 years) involvement across qualitative research investigating their food practice perspectives.Design:A scoping review was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Scoping Reviews (PRISMA-ScR). Six electronic databases were searched up until March 2023 (Cochrane, CINAHL, Embase, ERIC, Medline and PsychInfo). The Wellcome Framework for young people’s involvement in health research guided data extraction. Data were described according to inclusiveness, geography, food-related study topic, research stage and method, and child involvement.Results:The search identified 120 peer-reviewed studies (134 papers). Active participation was only seen within research implementation stages (i.e. data collection (n134), analysis (n31), dissemination (n9) and re-design (n7)). More passive forms of participation were identified in research design stages (i.e. agenda setting, resourcing and design). Studies that utilised participatory research methodologies and developmentally appropriate and engaging methods (e.g. PhotoVoice) saw more active participation by children.Conclusion:This review identified a lack of opportunities for children’s active participation in all stages of food practice research. Without a radical shift towards providing these opportunities, food and nutrition initiatives, policies or further research that do not meet the needs of children’s food-related worlds will continue to be developed. Instead, researchers and their institutions need to advocate for and, where possible, provide voluntary opportunities for children to actively participate in food practice research.
Impact‐Induced Seafloor Deformation From Submarine Landslides: Diagnostic of Slide Velocity?
Authors: Lenz Brandi L. , Griffith W. Ashley , Sawyer Derek E. 
Published: September 2023

AbstractSubmarine landslides shape continental margins, transfer massive amounts of sediment downslope, and can generate deadly and destructive tsunamis. Submarine landslides are common globally, yet constraining hazard potential of future events is limited by a short historical record and a wide range of possible slide dynamics. We test a novel approach to investigate slide dynamics using properties of the deformation zone induced by a large submarine landslide along the Cascadia margin, offshore Oregon. We use a simple model of a line load on a poroelastic half space to show the deformation zone size required rapid transport and deceleration. We argue that the slide moved at high speeds, aided by low dynamic frictional resistance, suggesting this event could have generated a tsunami. This method is applicable where slide‐induced impact zones are observed.
Two Classes of Equatorial Magnetotail Dipolarization Fronts Observed by Magnetospheric Multiscale Mission: A Statistical Overview
Authors: Alqeeq S. W. , Le Contel O. , Canu P. , Retinò A. , Chust T. , Mirioni L. , Chuvatin A. , Nakamura R. , Ahmadi N. , Wilder F. D. , Gershman D. J. , Khotyaintsev Yu. V. , Lindqvist P.‐A. , Ergun R. E. , Burch J. L. , Torbert R. B. , Fuselier S. A. , Russell C. T. , Wei H. Y. , Strangeway R. J. , Bromund K. R. , Fischer D. , Giles B. L. , Saito Y. 
Published: September 2023

AbstractWe carried out a statistical study of equatorial dipolarization fronts (DFs) detected by the Magnetospheric Multiscale mission during the full 2017 Earth's magnetotail season. We found that two DF classes are distinguished: class I (74.4%) corresponds to the standard DF properties and energy dissipation and a new class II (25.6%). This new class includes the six DF discussed in Alqeeq et al. (2022, https://doi.org/10.1063/5.0069432) and corresponds to a bump of the magnetic field associated with a minimum in the ion and electron pressures and a reversal of the energy conversion process. The possible origin of this second class is discussed. Both DF classes show that the energy conversion process in the spacecraft frame is driven by the diamagnetic current dominated by the ion pressure gradient. In the fluid frame, it is driven by the electron pressure gradient. In addition, we have shown that the energy conversion processes are not homogeneous at the electron scale mostly due to the variations of the electric fields for both DF classes.
A “Boreing” Night of Observations of the Upper Mesosphere and Lower Thermosphere Over the Andes Lidar Observatory
Authors: Hecht J. H. , Liu A. Z. , Fritts D. C. , Walterscheid R. L. , Gelinas L. J. , Rudy R. J. 
Published: September 2023

AbstractA very high‐spatial resolution (∼21–23 m pixel at 85 km altitude) OH airglow imager at the Andes Lidar Observatory at Cerro Pachón, Chile observed considerable ducted wave activity on the night of 29–30 October 2016. This instrument was collocated with a Na wind‐temperature lidar that provided data revealing the occurrence of strong ducts. A large field of view OH and greenline airglow imager showed waves present over a vertical extent consistent with the altitudes of the ducting features identified in the lidar profiles. While waves that appeared to be ducted were seen in all imagers throughout the observation interval, the wave train seen in the OH images at earlier times had a distinct leading nonsinusoidal phase followed by several, lower‐amplitude, more sinusoidal phases, suggesting a likely bore. The leading phase exhibited significant dissipation via small‐scale secondary instabilities suggesting vortex rings that progressed rapidly to smaller scales and turbulence (the latter not fully resolved) thereafter. The motions of these small‐scale features were consistent with their location in the duct at or below ∼83–84 km. Bore dissipation caused a momentum flux divergence and a local acceleration of the mean flow within the duct along the direction of the initial bore propagation. A number of these features are consistent with mesospheric bores observed or modeled in previous studies.
Mechanisms Associated With Tropospheric Dry Static Stability Change During the Last Glacial Maximum
Authors: Xie Zhiang , Dong Li , Liu Kaijun 
Published: September 2023

AbstractThe processes governing tropospheric stratification alterations during the Last Glacial Maximum (LGM) are investigated using the Paleoclimate Modeling Intercomparison Project Phase 3/4 (PMIP3/PMIP4) simulations. The results demonstrate a decrease in static stability in the tropics during both December‐January‐February (DJF) and June‐July‐August (JJA), while an increase is observed in the extratropics during DJF. Further analysis reveals that the rise in static stability over high‐latitude ocean is driven by shifts in surface frozen lines, whereas the increased static stability over ice sheet margins is due to the cooling effect of ice sheet slopes. The study finds that the dry static stability change in ice sheet‐covered areas remains significant and robust in both PMIP3 and PMIP4. However, a weaker stabilization signal is detected in the North Atlantic in PMIP4. These findings provide valuable insights into the processes shaping tropospheric stratification during the LGM and underscore the importance of accounting for ice sheet effects in paleoclimate simulations.
Secreted LRPAP1 binds and triggers IFNAR1 degradation to facilitate virus evasion from cellular innate immunity
Authors: Li Huangcan , Wang Xiong , Wang Yiran , Li Yichen , Chen Ying , Wong Yin-Ting , He Jufang , He Ming-Liang 
Published: September 2023

AbstractThe crucial role of interferon (IFN) signaling is well known in the restriction or eradication of pathogen invasion. Viruses take a variety of ways to antagonize host defense through eliminating IFN-signaling intracellularly for decades. However, the way by viruses target IFN-signaling extracellularly has not been discovered. Infection by both coronavirus SARS-CoV-2 and enterovirus 71 (EV71 or EV-A71) can cause severe diseases such as neurological disorders and even death in children.1–3 Here, we show evidence that the protease of SARS-CoV-2 (3CLpro) and EV71 (2Apro) upregulates the expression and secretion of LDL-receptor-related protein-associated protein 1 (LRPAP1). As a ligand, the N-terminus of secreted LRPAP1 binds with the extracellular domain of IFNAR1 that triggers the receptor ubiquitination and degradation and promotes virus infection both in vitro, ex vivo in the mouse brain, and in vivo in newborn mice. A small peptide from the N-terminus of LRPAP1 effectively binds and causes IFNAR1 degradation that enhances both DNA and RNA viral infections, including herpesvirus HSV-1, hepatitis B virus (HBV), EV71, and beta-coronavirus HCoV-OC43; whereas α2M, a LRPAP1 inhibitor, arrests virus infections by stabilizing IFNAR1. Our study demonstrates a new mechanism used by viruses for evading host cell immunity, supporting a strategy for developing pan-antiviral drugs.
Identification of a miRNA multi-targeting therapeutic strategy in glioblastoma
Authors: Bassot Arthur , Dragic Helena , Haddad Sarah Al , Moindrot Laurine , Odouard Soline , Corlazzoli Francesca , Marinari Eliana , Bomane Alexandra , Brassens Augustin , Marteyn Antoine , Hibaoui Youssef , Petty Tom J. , Chalabi-Dchar Mounira , Larrouquere Louis , Zdobnov Evgeny M. , Legrand Noémie , Tamburini Jérôme , Lincet Hubert , Castets Marie , Yebra Mayra , Migliorini Denis , Dutoit Valérie , Walker Paul R. , Preynat-Seauve Olivier , Dietrich Pierre-Yves , Cosset Érika 
Published: September 2023

AbstractGlioblastoma (GBM) is a deadly and the most common primary brain tumor in adults. Due to their regulation of a high number of mRNA transcripts, microRNAs (miRNAs) are key molecules in the control of biological processes and are thereby promising therapeutic targets for GBM patients. In this regard, we recently reported miRNAs as strong modulators of GBM aggressiveness. Here, using an integrative and comprehensive analysis of the TCGA database and the transcriptome of GBM biopsies, we identified three critical and clinically relevant miRNAs for GBM, miR-17-3p, miR-222, and miR-340. In addition, we showed that the combinatorial modulation of three of these miRNAs efficiently inhibited several biological processes in patient-derived GBM cells of all these three GBM subtypes (Mesenchymal, Proneural, Classical), induced cell death, and delayed tumor growth in a mouse tumor model. Finally, in a doxycycline-inducible model, we observed a significant inhibition of GBM stem cell viability and a significant delay of orthotopic tumor growth. Collectively, our results reveal, for the first time, the potential of miR-17-3p, miR-222 and miR-340 multi-targeting as a promising therapeutic strategy for GBM patients.
Elucidating the nature of the proton radioactivity and branching ratio on the first proton emitter discovered 53mCo
Authors: Sarmiento Luis G. , Roger Thomas , Giovinazzo Jérôme , Brown B. Alex , Blank Bertram , Rudolph Dirk , Kankainen Anu , Alvarez-Pol Héctor , Raj Alex Arokia , Ascher Pauline , Block Michael , Caamaño-Fresco Manuel , Caceres Lucia , Canete Laetitia , Cox Daniel M. , Eronen Tommi , Fahlander Claes , Fernández-Domínguez Beatriz , Forsberg Ulrika , Lois-Fuentes Juan , Gerbaux Mathias , Gerl Jürgen , Golubev Pavel , Grévy Stéphane , Grinyer Gwen F. , Habermann Tobias , Hakala Jani , Jokinen Ari , Kamalou Omar , Kojouharov Ivan , Kolhinen Veli S. , Koponen Jukka , Kurz Nikolaus , Lalović Nataša , Lorenz Christian , Mauss Benoit , Mentana Alice , Moore Iain D. , Ortega Moral Aurora , Pancin Julien , Papadakis Philippos , Pibernat Jérôme , Piot Julien , Pohjalainen Ilkka , Reinikainen Juuso , Rinta-Antila Sami , Schaffner Henning , Sorlin Olivier , Stodel Christelle , Thomas Jean-Charles , Versteegen Maud , Voss Annika 
Published: September 2023

AbstractThe observation of a weak proton-emission branch in the decay of the 3174-keV 53mCo isomeric state marked the discovery of proton radioactivity in atomic nuclei in 1970. Here we show, based on the partial half-lives and the decay energies of the possible proton-emission branches, that the exceptionally high angular momentum barriers, $${{{{{{\mathcal{l}}}}}}}_{{{{{{\rm{p}}}}}}}=9$$

l

p

=
9
and $${{{{{{\mathcal{l}}}}}}}_{{{{{{\rm{p}}}}}}}=7$$

l

p

=
7
, play a key role in hindering the proton radioactivity from 53mCo, making them very challenging to observe and calculate. Indeed, experiments had to wait decades for significant advances in accelerator facilities and multi-faceted state-of-the-art decay stations to gain full access to all observables. Combining data taken with the TASISpec decay station at the Accelerator Laboratory of the University of Jyväskylä, Finland, and the ACTAR TPC device on LISE3 at GANIL, France, we measured their branching ratios as bp1 = 1.3(1)% and bp2 = 0.025(4)%. These results were compared to cutting-edge shell-model and barrier penetration calculations. This description reproduces the order of magnitude of the branching ratios and partial half-lives, despite their very small spectroscopic factors.
The road to approved vaccines for respiratory syncytial virus
Authors: Ruckwardt Tracy J. 
Published: September 2023

AbstractAfter decades of work, several interventions to prevent severe respiratory syncytial virus (RSV) disease in high-risk infant and older adult populations have finally been approved. There were many setbacks along the road to victory. In this review, I will discuss the impact of RSV on human health and how structure-based vaccine design set the stage for numerous RSV countermeasures to advance through late phase clinical evaluation. While there are still many RSV countermeasures in preclinical and early-stage clinical trials, this review will focus on products yielding long-awaited efficacy results. Finally, I will discuss some challenges and next steps needed to declare a global victory against RSV.
Natural capital investments in China undermined by reclamation for cropland
Authors: Kong Lingqiao , Wu Tong , Xiao Yi , Xu Weihua , Zhang Xiaobiao , Daily Gretchen C. , Ouyang Zhiyun 
Published: September 2023

AbstractGlobally, rising food demand has caused widespread biodiversity and ecosystem services loss, prompting growing efforts in ecological protection and restoration. However, these efforts have been significantly undercut by further reclamation for cropland. Focusing on China, the world’s largest grain producer, we found that at the national level from 2000 to 2015, reclamation for cropland undermined gains in wildlife habitat and the ecosystem services of water retention, sandstorm prevention, carbon sequestration and soil retention by 113.8%, 63.4%, 52.5%, 29.0% and 10.2%, respectively. To achieve global sustainability goals, conflicts between inefficient reclamation for cropland and natural capital investment need to be alleviated.
From alternative conceptions of honesty to alternative facts in communications by US politicians
Authors: Lasser Jana , Aroyehun Segun T. , Carrella Fabio , Simchon Almog , Garcia David , Lewandowsky Stephan 
Published: September 2023

AbstractThe spread of online misinformation on social media is increasingly perceived as a problem for societal cohesion and democracy. The role of political leaders in this process has attracted less research attention, even though politicians who ‘speak their mind’ are perceived by segments of the public as authentic and honest even if their statements are unsupported by evidence. By analysing communications by members of the US Congress on Twitter between 2011 and 2022, we show that politicians’ conception of honesty has undergone a distinct shift, with authentic belief speaking that may be decoupled from evidence becoming more prominent and more differentiated from explicitly evidence-based fact speaking. We show that for Republicans—but not Democrats—an increase in belief speaking of 10% is associated with a decrease of 12.8 points of quality (NewsGuard scoring system) in the sources shared in a tweet. In contrast, an increase in fact-speaking language is associated with an increase in quality of sources for both parties. Our study is observational and cannot support causal inferences. However, our results are consistent with the hypothesis that the current dissemination of misinformation in political discourse is linked to an alternative understanding of truth and honesty that emphasizes invocation of subjective belief at the expense of reliance on evidence.