bluuebunny/crossref_metadata_2025_split huggingface dataset:
Plasma levels and dietary intake of minerals in patients with type 2 diabetes and chronic kidney disease
Authors: Mudili Sivaprasad , Tattari Shalini , Sahay Manisha , Sahay Rakesh , Manavalan Satyanaryanan , Geereddy Bhanuprakash Reddy 
Published: May 2023

Abstract

Diabetic kidney disease (DKD) is the primary cause of chronic kidney disease (CKD) worldwide. Altered mineral levels leading to adverse outcomes are widely reported in diabetes, but studies regarding their status in DKD are limited. To explore the status of minerals, a hospital-based case-control study was taken up with 54 healthy controls (C) and 140 subjects with type 2 diabetes wherein 74 subjects with diabetes, and CKD formed the DKD group, and 66 subjects with diabetes, no CKD formed the DNCKD group. High-resolution inductively coupled plasma mass spectrometry was used to evaluate the blood levels of minerals (Ca, V, Cr, Mn, Fe, Co, Cu, Zn, and Se), and raw food-based food frequency questionnaire for dietary intakes. The median values of plasma Ca in the DKD group were significantly lower compared with the DNCKD and C groups (10.5 mg/dL vs. 11.0 mg/dL and 11.7 mg/dL, p < 0.001). Furthermore, plasma Ca levels lowered with declining kidney function, as evidenced by the estimated glomerular filtration rate (eGFR) and albuminuria segregation. Dietary intake of minerals did not correlate with the corresponding plasma levels. However, in the DKD group, eGFR correlated positively with the plasma levels of Ca (r = 0.422, p = 0.001), Cr (r = 0.351, p = 0.008), Mn (r = 0.338, p = 0.011), Fe (r = 0.403, p = 0.002), Cu (r = 0.274, p = 0.041) and negatively with Se (r= -0.486, p < 0.001). Plasma Ca levels are lower in the DKD group with a strong positive association with eGFR, indicating its role in predicting the onset and progression of kidney function decline.
Impacts of aquaculture nutrient sources: ammonium uptake of commercially important eucheumatoids depends on phosphate levels 1
Authors: Narvarte Bienson Ceasar , Hinaloc Lourie Ann , Gonzaga Shienna Mae , Roleda Michael 
Published: May 2023

Abstract

In an integrated multitrophic aquaculture (IMTA) system, seaweeds serve as extractive species that utilize excess nutrients thereby reducing the risk of eutrophication and promoting sustainable aquaculture. However, the use of excessive fish feeds and the resultant fecal waste as nutrient streams can contribute to variations in nitrogen and phosphorus levels (e.g., primarily NH4+ and PO4-3) in the surrounding area, and this may impact the physiology of the integrated seaweeds particularly on how these species take up inorganic nutrients. In this study, the effect of different PO4-3 levels on NH4+ uptake of the three commercially important eucheumatoids Kappaphycus alvarezii, Kappaphycus striatus and Eucheuma denticulatum was examined under laboratory conditions. Seaweed thalli (n = 4) were incubated in seawater media containing 30 µM NH4+, representing eutrophic conditions, and 0, 0.5, 1.0, 1.5, 3.0 or 5.0 µM PO4-3 for 1 h under a saturating light level of 116 ± 7.13 µmol photons m-2 s-1 inside a temperature-controlled laboratory. Species-specific responses to PO4-3 levels were observed. For K. alvarezii, maximum NH4+ uptake (17.8 ± 1.6 µmol gDW-1 h-1) was observed at 0.5 µM PO4-3 and the uptake rate declined at higher PO4-3 levels. For K. striatus, the NH4+ uptake increases with increasing PO4-3 levels, with maximum N-uptake (6.35 ± 0.9 µmol gDW-1 h-1) observed at 5.0 µM PO4-3. For E. denticulatum, maximum NH4+ uptake (14.6 ± 1.4 µmol gDW-1 h-1) was observed at 1.0 µM PO4-3. Our results suggest that, among the three eucheumatoid species, the NH4+ uptake of K. striatus persist even at high levels of PO4-3. However, our results also showed that K. striatus had the lowest range of NH4+ uptake rates. These results should be taken into consideration when incorporating eucheumatoids in IMTA system where PO4-3 levels significantly vary in space and time.
Rumour detection on social media through Ensemble deep learning model
Authors: rani neetu 
Published: May 2023

Abstract
The widespread dissemination of several rumours and fake news has extremely affected many business organizations. Rumours or fake news spread and go viral on social websites causing significant social, business and political problem around the world. Fake news distorts public belief, affects companies reputation, disturbs community, reduces government integrity, makes business vulnerable and creates an enormous danger to the social constancy. This paper proposes a novel algorithm to detect rumour spread through tweeter. Various advanced machine learning techniques: Random Forest, Gradient Boosting, Adaboost and Hard Voting classifier are applied to detect the rumours from online social media through tweeter and Facebook. The proposed model is based upon the CNN-BiLSTM-BiGRU approach which efficiently classifies tweets among rumours and non-rumours category. The proposed model provides 99% accuracy and outperforms other baseline models like Random Forest, AdaBoost, Gradient Boosting, and Hard Voting. This hybrid recommender framework can be a more beneficial system to detect rumours at earlier stages from online platforms.
Error Correcting HTR’ed Byzantine Text
Authors: Pavlopoulos John , Kougia Vasiliki , Platanou Paraskevi , Shabalin Stepan , Liagkou Konstantina , Papadatos Emmanouil , Essler Holger , Camps Jean-Baptiste , Fischer Franz 
Published: May 2023

Abstract
The automated correction of errors in the Handwritten Text Recognition (HTR) output can be challenging and is far from solved. To address this challenge, we set up a shared task on AIcrowd that received 271 submissions, of which very few succeed. This paper presents the datasets, the best methods, and experimental analysis in error-correcting HTRed manuscripts and papyri in Byzantine Greek, the language that followed Classical and preceded Modern Greek. By using recognised and transcribed data from seven centuries, the two best-performing methods are compared, one based on a neural encoded-decoder architecture and the other based on linguistic knowledge. We show that the recognition error rate can be reduced by both, up to 2.5 points at the level of characters and up to 15 at the level of words, also highlighting the weak and strong points of each.
Diversity and evolution of the vertebrate chemoreceptor gene repertoire
Authors: Policarpo Maxime , Baldwin Maude , Casane Didier , Salzburger Walter 
Published: May 2023

Abstract
Chemoreception – the ability to smell and taste – is an essential sensory modality of most animals. The number and type of chemical stimuli that animals can perceive depends primarily on the diversity of chemoreceptors they possess and express. In vertebrates, six families of G protein-coupled receptors form the core of their chemosensory system, the olfactory/pheromone receptor gene families OR, TAAR, V1R and V2R, and the taste receptors T1R and T2R. Here, we provide the most comprehensive study to date of the vertebrate chemoreceptor gene repertoire and its evolutionary history. Through the examination of 2,210 vertebrate genomes, we uncover substantial differences in the number and composition of chemoreceptors across vertebrates. We show that the chemoreceptor gene families are co-evolving, highly dynamic, and characterized by lineage-specific expansions (for example, OR in tetrapods; TAAR, T1R in teleosts; V1R in mammals; V2R, T2R in amphibians) and losses. Overall, amphibians, followed by mammals, are the vertebrate clades with the largest chemoreceptor repertoires. While marine tetrapods feature a convergent reduction of chemoreceptor numbers, the number of OR genes correlates with habitat in mammals and birds and with migratory behavior in birds, and the taste receptor repertoire correlates with diet in mammals and with aquatic environment in fish.
WITHDRAWN: Comparative Evaluation of Palatal Rugae and Lip Print Patterns with Different Malocclusions in Children Aged 6-12 Years – A Cross-Sectional Study
Authors: jain mansi , Sogi H.P. Suma , Kapoor Roopam , Dhir Saru , Sukesh Sonali , Kashalkar Bhairavi 
Published: May 2023

Abstract
INTRODUCTION
The comparative assessment of different types of palatal rugae and lip prints with malocclusion could give us early evidence about the type of developing malocclusion. An early intervention could help achieve better orofacial structure.
AIM
To establish a correlation between different types of malocclusion with palatal rugae patterns and lip print patterns in children aged 6–12 years old.
MATERIALS AND METHOD
A total of 288 co-operative patients were selected and observed for patterns of palatal rugae using the Thomas and Kotze classification. Lip prints were recorded using the lipstick-cellophane technique and visualized using the Suzuki and Tsuchihashi classification. Malocclusion was compared with lip print and palatal rugae patterns.
RESULTS
The wavy type of palatal rugae pattern was predominant in Class I and II, while the curved type was most commonly seen in the Class III permanent molar relationship. The wavy type of palatal rugae pattern was predominant in Class I, and the curved type was seen more in Class II. Type II lip print pattern was observed in Class I, whereas Type IV lip print pattern was predominant in Class II, and Type V lip print pattern in Class III permanent molar relationship. The Type IV lip print pattern was seen in Class II, and Type II in Class I primary canine relationship.
CONCLUSION
No statistically significant correlation was found between dental malocclusion and palatal rugae pattern. A definite interpretation exists that lip print patterns offer many distinct advantages as a screening tool for malocclusion than palatal rugae patterns.
Identification and Prioritization of Accident prone Areas using Accident Information. A Case of Study of Metehara-Dengego Road Segment in Oromia Regional State, West Hararghe Zone
Authors: Olkeba Sagni Temesgen , Beyecha Daba Adugna , Merga Leta Jirata , Merga Biratu Bobo 
Published: May 2023

Abstract
The Road traffic crashes particularly in West Hararghe Zone along Metehara- Dengego road segment on main asphalt has not been studied. Hence, in this study road traffic data of three years (2018–2021) were obtained from five (Gumbi Bordode, Mieso, Chiro, Tulo and Doba) towns of traffic police department and West Hararghe Zone transport Authority in Oromia Regional State. The crash severity index developed by the Roads and Traffic Authority of New South Wales was utilized for ranking and prioritizing of hotspot areas based on accident information. The latest instrument, Global Positioning System was used to collect X, Y, Z coordinates of hot spot areas based the Crash Severity Index (CSI) value. The point data obtained using Global Positioning System and crash severity index value were added to road network data using ArcGIS. The results of finding indicates a total of 263 Road traffic crashes were occurred in the five towns from which about 120 fatal occurred on people, 74 injuries and 69 damaged properties. Based on the value of Crash Severity Index and Crash Frequency (CF) of RTCs top nine hot spot areas were identified and ranked which requires high attention to protect road user and property from damage and loss life. Thus, the government and other concerned stakeholders should provide public education, installing road infrastructure, road marking, traffic signs, improving sight distance and awareness creation to reduce threat of fatalities, injuries and property damage due to RTCs along towns in which the main roads passes in West Hararghe Zone.
Rice Nutraceuticals and Bioactive Compounds: Extraction, Characterization
and Antioxidant Activity: A Review
Authors: Zubair Muhammad , Anwar Farooq , Arshad Insha , Malik Shanza , Zafar Muhammad Nadeem 
Published: May 2023

Abstract:
Rice (Oryza sativa L.), a cereal grass, belongs to the genus Oryza from the family Poaceae,
which encompasses twenty-five species cultured in many countries of Asia, and partly in the
rest of the world. From these species, two viz. Oryza sativa (O. sativa) Asian rice and Oryza glaberrima
(O. glaberrima) African rice are commonly found and the most widely consumed staple
food by a large part of the human population in the world, especially in Asia due to their nutritional
and nutraceutical prospects. Rice, a popular source of carbohydrates, also contains a good amount
of dietary fiber, minerals (Ca, Zn, Se, P, K, Mg, Fe, and Mn), protein and vitamin B along with
several other medicinally important bioactives such as tocols (α-tocopherols and α-tocotrienols) (ßsitosterol)
phenolic acids, flavonoids (apiginine), and oryzanol (24-Methylenecylcoartanyl transferulate).
Rice bran is a byproduct of the rice polishing industry and is valuable in terms of containing
15-20% high-value oil. Because of the natural antioxidants present in rice, several medicinal
benefits and biological properties can be attributed to rice consumption. The nutrient profile of rice
varies based on several factors, such as grains (white, brown, red, and black/purple), the extent of
polishing, and the preparation method. Considering the importance of rice as a traditional diet rich
in high-value bioactives, together with the existing gap of related information, it is worthwhile to
assemble a comprehensive review that focuses on the detailed profile of valuable nutrients and
high-value phytochemicals and biological activities of rice to explore its functional food and
nutraceutical applications. This review attempts to provide collective information on the essential
rice cereal for its nutritional and antioxidant potential.
A Review of Anti-Inflammatory Phytoconstituents Used in Herbal
Cosmeceuticals for the Treatment of Atopic Dermatitis
Authors: Gangane Purushottam , Sharma Vidhi , Selokar Mokshada , Vidhate Dipali , Pawar Kapil , Mahajan Nilesh 
Published: May 2023

Abstract:
Skin diseases such as atopic dermatitis affect babies, children, and adults and are characterized
by red skin/spots, severe itching that appears on the face, head, legs, neck, and hands, and various
causes of illness caused by various external and internal factors. AD is a type IIgE-mediated hypersensitivity
reaction. Herbal preparations treat various dermatological diseases like dry skin, melasma, acne,
and eczema. Cosmeceuticals are the connection between cosmetics and medicine, one of the world's
most used forms of medicine. Cosmeceuticals products are beneficial in treating AD. Herbal cosmetics
play a major role in curing various skin diseases. Today, various herbs used in cosmeceuticals have
anti-inflammatory, antioxidant, antibacterial, and antiseptic effects. Compared to synthetic preparations,
herbal preparations have fewer side effects. This review paper introduces Atopic dermatitis, cosmeceutical,
and various phytoconstituents like gallic acid, ferulic acid, boswellic acid, quercetin, and
naringenin tetra hydroxyl flavanol glycoside, glycyrrhizic acid, epigallocatechin gallate, etc., used in
atopic dermatitis.
Research Progress on Activity and Biosynthesis of Diketopiperazines
Authors: Liu Bing , Lu Ruiyang , Chen Ning , Yuan Hongliang , Zhao Jintong , Zhao Yuechen 
Published: May 2023

Abstract:
Diketopiperazines (DKPs) are mainly produced by microorganisms. In recent years, active
natural products with DKPs structure have been isolated from marine bacteria, actinomycetes and
fungi. The stable six-membered ring framework makes DKPs a vital pharmacophore in medicinal
chemistry. Several recent studies have demonstrated that it has antibacterial, antifungal, antiviral, antitumor,
immunosuppressive, neuroprotective, anti-malaria, anti-prion, and anti-hyperglycemia properties.
Some DKPs are signaling molecules for intercellular communication, which can activate or
inhibit bacterial Lux R-mediated quorum sensing. They are considered potential new anti-infective
drugs that could control biofilm formation by interfering with information communication between
microbes. DKPs possess excellent biological activities and have received extensive attention from
medicinal chemistry workers. Bioactivity studies of DKPs have revealed that many highly active lead
compounds exist in antibacterial, antitumor, and antiviral fields and in treating neurological disorders.
This paper reviews the research progress of diketopiperazines in the past ten years.
Boswellic Acids: A Critical Appraisal of Their Therapeutic and Nutritional Benefits in Chronic Inflammatory Diseases
Authors: Solanki Neeta , Gupta Gaurav , Chellappan Dinesh Kumar , Singh Sachin Kumar , Gulati Monica , Paudel Keshav Raj , Hansbro Philip M , Dua Kamal , Bhan Suraj , Saini Manisha , Dureja Harish 
Published: May 2023

Background:
In the last few decades, it has been largely perceived that the factors affecting the immune system and its varying pathways lead to the pathological progression of inflammation and inflammatory conditions. Chronic inflammation also contributes to common diseases, such as diabetes mellitus, ischemic heart disease, cancer, chronic renal inflammatory disease, non-alcoholic fatty hepat-ic disease, autoimmune diseases and neurodegenerative diseases.

Objective:
Interestingly, plant sources and secondary metabolites from plants have been increasingly employed in managing acute and chronic inflammatory diseases for centuries. Boswellic acids are pentacyclic triterpenoidal moieties obtained from the oleo gum resin of different Boswellia species.

Methods:
Detailed data was collected revealing the anti-inflammatory potential of Boswellic acids through various databases.

Results:
These are pharmacologically active agents that possess promising anti-inflammatory, anti-arthritic, antirheumatic, anti-diarrheal, anti-hyperlipidemic, anti-asthmatic, anti-cancer, and anti-microbial effects.

Conclusion:
Boswellic acids have been in use since ancient times primarily to treat acute and chronic inflammatory diseases. This review discusses the various mechanisms underlying the inflammatory process and the necessity of such natural products as a medication to treat inflammatory diseases. In addition, a discussion has also been extended to understand the primary targets involved in inflamma-tion. The review further explores the therapeutic potential of boswellic acids in
Examining the Role of Social Media Marketing on Brand Love and Its Impact on Brand Centrality: The Study of Local Fashion Brands for the Millennials
Authors: Mayasari Iin , Haryanto Handrix Chris , Hutagaol Olivia Deliani , Ramadhan Adam Rizky , Amir Iwan 
Published: May 2023

Purpose: Local fashion brands are an important issue for millennial consumers. To create their love of local fashion brands, social media marketing is necessary. The study also examines brand love's effects on local fashion brands' centrality. This study also investigates brand love and centrality’s impact on the repurchase intention. Design/ Methodology/Approach: The data were taken using survey methods with questionnaires developed by previous researchers. A partial least squares regression was used to test the hypotheses. Findings: This study shows that social media marketing can create conditions for consumers to develop brand love, but brand love still needs to be able to develop brand centrality. This study also shows that although brand love has yet to create brand centrality, the concept of brand love can influence the repurchase intention. At the same time, brand centrality also affects the repurchase intention. Originality/value: This is the first study analyzing millennials’ brand love toward fashion clothing brands and the analysis of the influence of social media marketing on brand love and its impact on brand centrality.
LAYANAN BIMBINGAN KELOMPOK DENGAN TEKNIK MODELING UNTUK MENCEGAH PERILAKU BULLYING PESERTA DIDIK DI SMAN 1 SINDANGKERTA
Authors: Melati Tima , Sobari Teti , Septian Muhammad Rezza 
Published: May 2023

This research was carried out with the aim of knowing the implementation of group guidance services with modeling techniques, student responses, knowing the difficulties experienced by students and knowing the obstacles faced by BK teachers when implementing group guidance services with modeling techniques to prevent bullying behavior in students. class XI. The method used in this research is descriptive qualitative method. The subjects of this study were six class XI participants who were selected based on the results of observations and interviews so that students would not become bullies. The data collection procedure used observation and interviews. Data analysis in this study used source triangulation through the data collection stage, the data reduction stage, the data display stage, and the conclusion drawing stage. Based on the results of providing group guidance services with modeling techniques to prevent bullying behavior in SMAN 1 Sindangkerta students that the implementation of services provided by BK teachers is in accordance with the RPL made and proven to help guidance and counseling teachers in preventing bullying behavior in students, then The response shown by students was very good, it was seen from the enthusiasm of students in participating in this activity, students had obstacles when participating in the service, namely students did not focus on the material provided by the BK teacher, then the obstacle for the BK teacher was in the process of providing services at the activity stage. students tend to be less focused so that guidance and counseling teachers must be more creative in an effort to restore focus on students.Â Keywords: Group guidance, modeling, bullyingÂ
BIMBINGAN KELOMPOK MELALUI TEKNIK DISKUSI UNTUK MENINGKATKAN KEPERCAYAAN DIRI SISWA SMA KELAS X IPA
Authors: Alawiyah Putri , Hendriana Heris , Irmayanti Rima 
Published: May 2023

Self-confidence is a positive attitude and behavior of an individual that raises his ability to cultivate and develop a positive assesment, both toward himself and the environment and the situation he is facing. BK teacher and student responses to group guidance service with discussion techniques on student when implementing group guidance service with discussion techniques on the self-confidence of class X / IPA students at SMAN 1 Cipongkor. Qualitative descriptive research methods were collected trough observation, interviews and questinnaires. The scenario steps and their implementation are also in group guidance service with discussion techniques including group formation seen from the students self-confidence problem that have been reviewed by the BK teacher and the results of the AKPD given by the BK teacher, Providing material through video media to stimulate initial confidence for participants. Studen, share opinions about the material provided, conclude, and evaluate the implementation of services. The response of students in self-confidence during the implementation of group guidance services with discussion techniques.Â Keywords:Â Â Â Self Confidence, Group Guidance, Discussion Techniques
GAMBARAN KETERAMPILAN SELF REGULATED LEARNING SISWA SMP KELAS VIII SELAMA PEMBELAJARAN DARING
Authors: Gustiana Syifa Dewi , Rohaeti Euis Eti , Alawiyah Tuti 
Published: May 2023

This study purpose to describe the self regulated learning skills of grade VIII junior high school students during online learning at SMP Negeri 9 Cimahi. This research is based on the reality at school, where there are a number of students who have a level of self regulated learning below the average while participating in online learning. The method used in this research is a qualitative method with a descriptive type of research. This study uses interview and observation techniques to collect data. The informants in this study were junior high school students grade VIII totaling 3 people with the criteria of having low self-regulated learning during online learning. In terms of metacognitive, motivational and behavioral aspects, the results of this study indicate that during online learning, students find it difficult to organize themselves in independent study sessions. This study also found internal factors and external factors as two factors that affect students' self regulated learning.Â Keywords: Online Learning, Self Regulated Learning