bluuebunny/crossref_metadata_2025_split huggingface dataset:
Moving forward with elective vascular work: a reflection on the impact of COVID-19 on a regional vascular hub
Authors: Liu P , Cheema SM , Adeoye I , Theivacumar NS , Hussain ST , Malina M 
Published: May 2023

Introduction Following the initial COVID-19 surge in the UK, there was a national incentive for elective vascular surgery to be restricted to ‘clean’ sites to reduce perioperative cross-infection and subsequent mortality. We assessed the risk of dying from perioperatively acquired COVID-19 during the peak of the London outbreak. Methods Forty-three consecutive patients who had vascular (n=48) procedures in March and April 2020 at a regional hub serving five London hospitals were analysed. The patients were screened for COVID-19 in the 30-day postoperative period and the main outcome measure was mortality from COVID-19. A comparison was then made with patients who underwent minimally invasive procedures in our integrated interventional radiology department. Median follow-up was 41 days (interquartile range 8–58) overall. Results Three patients (7%) in the vascular group (median age 61 years, all diabetic, two male) died from COVID-19, all of whom tested positive postoperatively. Two others became positive but recovered. In comparison, two patients (2%) in the interventional radiology group died from COVID-19; however, one was positive prior to their procedure. Conclusion Only urgent vascular cases should be performed during a COVID-19 surge. However, with growing waiting lists for elective surgery following the pandemic’s second wave, further restrictions may not be a viable long-term solution. When prevalence of the disease is lower and if resources allow, resumption of care at ‘hot’ sites should be considered, if safety measures can be implemented. The advantages of minimally invasive surgery may also reduce risk.
North central London elective orthopaedic network: accelerating how we improve surgical practice in the NHS
Authors: Thompson JW , Ibrahim M , O’Brien A , Stewart A , Huxter W , Hurd R , Haddad FS 
Published: May 2023

In the era of patient centred medical practice, we are forced to regularly adapt our approach to keep up with the growing demands of an aging population while focusing on quality improvement, and reducing unwarranted variations in access to health services as well as in quality and outcomes. In a mission to address some of these challenges, the five north central London (NCL) clinical commissioning groups and five NCL National Health Service trusts currently undertaking adult elective orthopaedic surgery collaborated to propose and develop dedicated elective orthopaedic centres. The goal was to create an orthopaedic clinical network that will join together orthopaedic services under one quality improvement umbrella. We present this process, which provides an innovative model of service delivery and the genesis of an orthopaedic network.We believe this model offers essential principles with which future integrated care systems could engage: clinical leadership, early public involvement, proposal transparency, co-design through multiple trust collaboration, addressing health inequalities and establishing a system to deliver best practice care. Our ability to all come together (hospital trusts, patients and the public) is a clear example of the collaborative potential that our healthcare system has, and can be seen as a blueprint for future endeavours. We hope that the transformation of the NCL elective orthopaedic network through elective orthopaedic centres will provide a beneficial template to colleagues and public communities attempting to meet the enhancing demand on current orthopaedic services, and that this will improve the delivery of health services beyond the constraints of our locality.
Mycophenolate mofetil-based treatment for oral mucosal disease in a UK oral medicine department
Authors: Sin Sonia , Rogers Helen , Cowie Rachel , Staines Konrad , Hollén Linda , Shanahan Daire 
Published: May 2023

Introduction Mycophenolate mofetil (MMF) is often used in oral medicine. Reasons include its efficacy in treating inflammatory diseases, its steroid sparing property and its favourable side effects profile. There is, however, limited scientific evidence to justify its use in oral medicine. The aim of this study was to review the indications and prescribing practice relating to MMF in a tertiary oral medicine centre, and to document its tolerability and efficacy. Methods A retrospective record review was undertaken of patients prescribed MMF between January 2019 and January 2022 at Bristol Dental Hospital. Patients were identified from a local database set up to highlight and monitor departmental immunosuppressant medication usage. Medical records were assessed using a standardised data collection proforma. Results Twenty-five patients (20 female, 5 male; median age 64 years) were included in the study. The conditions for which MMF was prescribed comprised oral lichen planus (48%), mucous membrane pemphigoid (36%), pemphigus vulgaris (12%) and recurrent aphthous stomatitis (4%). Typically, MMF was prescribed at 500 mg twice daily. The median duration of treatment was 28 months. Side effects were documented in 52% of patients. In all cases, MMF was commenced owing to inadequate response to previous treatments. Over half (56%) of the patients discontinued systemic prednisolone while using MMF. Overall, 80% achieved complete clinical improvement. Conclusions MMF is effective and well tolerated in oral medicine patients. Its use is comparable with that documented in the dermatology literature.
Evaluation of Land Capability and Land Use Direction In the Krueng Peusangan Hilir Sub-watershed, Bireuen Regency
Authors: Akbar Halim , Sarifuddin Sarifuddin , Puarada Sakral Hasby 
Published: May 2023

The destruction of forests in watershed areas has now become a concern of many parties, resulting in floods, landslides, and droughts that continue to increase. Watershed damage is accelerated by increased utilization of natural resources due to population growth and economic development, conflicts of interest, and lack of integration between sectors between the upstream-middle-downstream areas. For this reason, it is necessary to assess land capability in a watershed so that land development follows the land capability class. The research was carried out in the Krueng Peusangan Hilir Sub-watershed, Bireuen Regency, Aceh, Indonesia, from October 2021 to February 2022, which is geographically located at 95°58''00” - 96°52''00” East Longitude and 5°06''00- 5°17 ''00" North Latitude. Land use in the study is dominated by dry land agriculture, covering an area of 19,100.28 ha with a topography area from 0-8% to 25-40%. A survey method by analyzing land capability classes at the study site was carried out for each land map unit (LMU) by comparing land conditions with the land capability evaluation Hockensmith and Steele’s criteria (overlaid of determined thematic maps). The result shows that soil erodibility decreased linearly with increasing organic matter in the soil. Soils with high organic matter content have high erodibility. For the limiting factor on slopes in land capability classes found in II, III, IV, and VI class categories that are found in all LMUs, if these LMUs are used for agricultural cultivation, soil conservation measures are needed, such as making mound terraces or canal mound terraces, planting in strips and using mulch. The results show that the land capability classes consisted of 16668.30 ha in the land capability II class, 4184.06 ha land capability in the III class, 4524.91 ha in the land capability IV class, and 190.79 ha land capability VI class with a factor inhibiting soil erodibility (medium – very high) and slopes (wavy - rather steep)
Plasma sterols and vitamin D are correlates and predictors of ozone-induced inflammation in the lung: A pilot study
Authors: Perryman Alexia N. , Kim Hye-Young H. , Payton Alexis , Rager Julia E. , McNell Erin E. , Rebuli Meghan E. , Wells Heather , Almond Martha , Antinori Jamie , Alexis Neil E. , Porter Ned A. , Jaspers Ilona 
Published: May 2023

BackgroundOzone (O3) exposure causes respiratory effects including lung function decrements, increased lung permeability, and airway inflammation. Additionally, baseline metabolic state can predispose individuals to adverse health effects from O3. For this reason, we conducted an exploratory study to examine the effect of O3exposure on derivatives of cholesterol biosynthesis: sterols, oxysterols, and secosteroid (25-hydroxyvitamin D) not only in the lung, but also in circulation.MethodsWe obtained plasma and induced sputum samples from non-asthmatic (n = 12) and asthmatic (n = 12) adult volunteers 6 hours following exposure to 0.4ppm O3for 2 hours. We quantified the concentrations of 24 cholesterol precursors and derivatives by UPLC-MS and 30 cytokines by ELISA. We use computational analyses including machine learning to determine whether baseline plasma sterols are predictive of O3responsiveness.ResultsWe observed an overall decrease in the concentration of cholesterol precursors and derivatives (e.g. 27-hydroxycholesterol) and an increase in concentration of autooxidation products (e.g. secosterol-B) in sputum samples. In plasma, we saw a significant increase in the concentration of secosterol-B after O3exposure. Machine learning algorithms showed that plasma cholesterol was a top predictor of O3responder status based on decrease in FEV1 (>5%). Further, 25-hydroxyvitamin D was positively associated with lung function in non-asthmatic subjects and with sputum uteroglobin, whereas it was inversely associated with sputum myeloperoxidase and neutrophil counts.ConclusionThis study highlights alterations in sterol metabolites in the airway and circulation as potential contributors to systemic health outcomes and predictors of pulmonary and inflammatory responsiveness following O3exposure.
A protocol for a controlled, pre-post intervention study to change attitudes toward child marriage in Southwestern Nigeria using targeted radio programming
Authors: Omobowale Olubukola , Omigbodun Olayinka , Egbokhare Olayinka , Koski Alissa 
Published: May 2023

Background
Child marriage hinders progress toward population health and development goals. Cost effective interventions that address the root causes of child marriage are needed to speed progress toward ending the practice. Nigeria is home to the largest number of married girls in Africa and many of these girls are members of the Hausa ethnic group, making efforts to tackle this issue particularly urgent among this population.

Methods
Radio programs have the potential to inform large numbers of people about the harms of child marriage and change their support for the practice at low cost. We will develop a series of radio programs that address gender inequitable attitudes that motivate child marriage among Hausa communities in Ibadan, Nigeria. The content of the series will be based on input from the Hausa community. A baseline survey that measures knowledge of and support for child marriage will be conducted among randomly selected samples of Hausa adults in two cities: Ibadan, which will serve as the intervention site, and Akure, the control site. The radio programs will then air on Hausa-language stations in Ibadan over a three-month period, with the aim of informing persons of the potential harms of child marriage and reducing their support for the practice. A follow-up survey with the same individuals surveyed at baseline will be conducted in both cities. We will measure the impact of this intervention by comparing changes in these outcomes over time in the intervention site (Ibadan) with changes in the same outcomes in the control site (Akure).

Conclusion
This study will investigate whether a series of targeted radio programs can reduce support for child marriage. The intervention is readily scalable and cost-effective and, if it effectively shifts attitudes toward child marriage, could represent a promising way of addressing child marriage in Nigeria.
Proposal of a Qualitative Content Analysis Process for a Solo Researcher
Authors: Kawamoto Marika , Koizumi Masanori , Yoshikane Fuyuki 
Published: May 2023

AbstractQualitative analytical methods are important in many academic fields, including informatics. Although qualitative content analysis (QCA) is used for text, a coding method for a solo researcher has rarely been discussed. This work suggests a systematic QCA process for single coding based on the inductive-dominant approach. We developed a single coding method with a practical example based on an 11-step process: (1) decide research questions and purposes, (2) collect texts for analysis, (3) determine the unit of analysis, (4) engage in partial inductive coding of the target texts, (5) analyze frequent words found in the text, (6) use these frequent words and inductive coding to create a temporary coding schema, (7) collaborate with multiple experts or researchers to verify the temporary coding schema, (8) code the entire text based on the coding schema, (9) after a certain period, re-code the text based on the coding schema to calculate the intra-rater reliability, (10) confirm the final version of the coding schema, and (11) develop categories through code abstraction. Our process is suitable for a single researcher and for analyzing various text types qualitatively from a specific and consistent perspective. This study provides an exploratory foundation for examining the single coding process.
Backseat Inclination Affects the Myoelectric Activation During the Inclined Leg Press Exercise in Recreationally Trained Men
Authors: Marchetti Paulo H. , Gomes Willy A. , Da Silva Josinaldo J. , Magalhaes Roberto A. , Teixeira Luis F. M. , Whiting William C. 
Published: May 2023

Abstract
Marchetti, PH, Gomes, WA, Da Silva, JJ, Magalhaes, RA, Teixeira, LFM, and Whiting, WC. Backseat inclination affects the myoelectric activation during the inclined leg press exercise in recreationally trained men. J Strength Cond Res 37(10): e541–e545, 2023—Changes in the angle between the seat and backrest during the inclined leg press (ILP) exercise may influence myoelectric activity. The purpose of this study was to evaluate the myoelectric activity between 2 different angles between the seat and backrest (90° and 125°) during the ILP exercise in recreationally trained men. Fifteen young, resistance-trained men (age: 26.8 ± 5.3 years, height: 173.8 ± 6.6 cm, total body mass: 81.6 ± 7.6 kg) performed 1 set of 10 repetitions at 70% of their body mass during the ILP exercise using 2 different angles between the seat and backrest (ILP90° and ILP125°). Surface electromyography (peak RMS90 and iEMG) was used to measure the myoelectric activity of the vastus lateralis (VL), biceps femoris (BF), and gluteus maximus (GM). A paired t test was used to measure differences in knee and hip joint displacement, peak RMS90, and iEMG between ILP90 and ILP125. The hip angle presented a greater displacement during the ILP125 when compared with ILP90 (p < 0.001), considering a similar knee joint displacement. For the VL, there was observed greater myoelectric activation (peak RMS90 and iEMG) during ILP125 when compared with ILP90 (p < 0.05). For the BF, there was observed greater myoelectric activation (peak RMS90 and iEMG) during ILP90 when compared with ILP125 (p < 0.05). However, GM did not present differences between ILP90 and ILP125. In conclusion, the angle between the seat and backrest (ILP90 or ILP125) altered the myoelectric activation of the VL and BF with no difference for the GM.
DIALEK KETURUNAN TOK LINGGI SEBAGAI SUMBER ISTILAH DAN KEARIFAN TEMPATAN
Authors: Jamal Rizal bin Razali  , Jamilah Bebe binti Mohamad  , Hassan Hasmadi bin 
Published: May 2023

Kertas kerja ini membincangkan perihal penggunaan istilah dalam sesuatu kerja buat yang dilakukan oleh komuniti keturunan Tok Linggi. Komuniti ini menggunakan Bahasa Melayu dialek Pahang dan tinggal di Kampung Relong, Kuala Lipis sejak hampir dua ratus tahun lampau. Bagi mendapatkan data, pengkaji menggunakan pendekatan kualitatif iaitu teknik wawancara, rakaman serta catatan dalam perbualan spontan sama ada secara aktif mahupun pasif. Daripada analisis yang dijalankan, terdapat pelbagai istilah yang mempunyai makna dan tujuan khusus bagi kerja buat tertentu. Istilah-istilah ini asalnya adalah kata atau rangkai kata yang ada dalam dialek mereka. Hal ini dapat dikaitkan dengan kearifan tempatan kerana pembinaan istilah ini melibatkan proses uji cuba yang telah melalui tempoh masa yang panjang. Penggunaan dialek sebagai istilah menunjukkan bahawa penggunaan bahasa (istilah) oleh sesebuah komuniti bahasa (orang Melayu keturunan Tok Linggi ini) sangat berkaitan dengan latar budayanya.
This paper discusses the use of terms in a work done by the community of Tok Linggi descendants. This community uses Pahang dialect Malay and lives in Kampung Relong, Kuala Lipis since almost two hundred years ago. In order to obtain data, the researcher used a qualitative approach that is interview techniques, recordings and notes in spontaneous conversations either actively or passively. From the analysis carried out, there are various terms that have specific meanings and purposes for specific work. These terms are originally words or phrases in their dialect. This can be linked to local wisdom because the construction of this term involves a trial and error process that has gone through a long period of time. The use of dialect as a term shows that the use of language (terms) by a language community (Malays descended from Tok Linggi) is closely related to its cultural background.
Psychedelic Sensationalism: An Analysis of the Schedule Classification of Psilocybin
Authors: Wood Elisabeth 
Published: May 2023

In 1970, the United States Drug Enforcement Administration passed the Controlled Substances Act. This statute classified and banned a variety of drugs including psilocybin, the psychoactive component found in Psilocybe Cubensis (also known as "Magic Mushrooms"). Though psilocybin was known to possess many medical benefits and cause no serious side effects, the Controlled Substances Act designated it as one of the most dangerous drugs, earning it a Schedule I classification. This meant possession and use incurred the highest level of legal punishment, and psilocybin could not be used under any circumstances, including in a medical setting. Based on biochemical properties alone, psilocybin does not fit the criteria to be a Schedule I drug, which suggests some other factors must have contributed to its legal classification. This paper analyzes primary and secondary sources to explore the anthropological and political motives that may have influenced psilocybin's schedule classification. The evidence that psilocybin's reputation in the eyes of the government was damaged due to its association with hippies and the counterculture movement of the 1960s and 1970s. This paper asserts that drug regulation was used as a form of social control that aimed to stifle the progressive ideals of the youth counterculture movement and reinforce conservative American ideals.
Evaluasi Kinerja Sub Das Krueng Jreu Kabupaten Aceh Besar
Authors: Purgawa Khairun , Basri Hairul , Syahrul Syahrul 
Published: May 2023

Abstrak. Dampak perubahan alih fungsi lahan merupakan kejadian di alam yang perlu dipahami untuk menentukan tindakan yang perlu dilakukan di waktu yang akan datang. Strategi pengelolaan DAS masih membutuhkan suatu inovasi pendekatan hidrologi dan lahan untuk memperbaiki situasi DAS. Penelitian ini bertujuan untuk mengevaluasi kinerja Sub DAS Krueng Jreu Berdasarkan Permenhut P.61 tahun 2014 tahun tentang Monitoring dan Evaluasi Pengelolaan Daerah Aliran Sungai yang mencakup karakteristik Lahan dan karakteristik hidrologi. Hasil penelitian menunjukan persentase lahan kritis yaitu 2,37% (0,023723 ha), Persentase persentase penutupan vegetasi yaitu 78,61% (18250,64) ha, Indeks Erosi sebesar 0,60, Koefisisien Rejim Aliran (KRA) sebesar 26,62 Koefisien Aliran Tahunan (KAT) didapatkan hasil sebesar 0,056, Muatan Sedimen didapatkan hasil 5,02 ton/ha/tahun, frekuensi banjir adalah 1 kali dalam kurun waktu lima tahun, Indeks Penggunaan Air sebesar 22917,30 m3/thn termasuk dalam kelas sangat baik (0,5). Berdasarkan hasil skoring 8 Sub kriteria evaluasi kinerja Sub DAS Krueng Jreu yang meliputi Penggunaan Lahan dan Tata Air maka didapatkan hasil akhir senilai 37,75 dengan katagori sangat baik yang berarti kondisi DAS dalam keadaan sangat baik jika di lihat dari penggunaan lahan dan tata air.Performance Evaluation of Krueng Jreu Sub-watershed, Aceh Besar DistrictAbstract. The impact of changes and land-use changes caused is an event in nature that needs to be understood to determine the actions that need to be taken in the future. The watershed management strategy still requires innovation to improve the watershed situation. This study aims to determine the performance of the Krueng Jreu sub-watershed based on the Regulation of the Minister of Forestry P.61 of 2014 concerning Monitoring and Evaluation of Watersheds which includes hydrological characteristics and characteristics. The results showed that critical land was 2.37% (0.023723 ha), the percentage of vegetation cover percentage was 78.61% (18250.64) ha, the Erosion Index was 0.60, the Flow Regime Coefficient (KRA) was 26.62 The Annual Flow Coefficient (KAT) yields 0.056, Sediment Load yields 5.02 tons/ha/year, the frequency of flooding is 1 time within five years, the Water Use Index is 22917.30 m3/yr included in the very good class. (0.5). Based on the scoring of 8 Sub Criteria for evaluating the performance of the Krueng Jreu Watershed which includes Land Use and Water Management, the final result is 37.75 with a very good category which means the watershed condition is in very good condition when viewed from land use and water management.
Analisa Efektifitas Pemecah Kemiri Di Kabupaten Solok Sumatera Barat
Authors: Putri Renny Eka , Sari Rise Prana , Hasan Ashadi 
Published: May 2023

Abstrak. Kemiri adalah tanaman perkebunan yang sangat banyak manfaatnya bagi masyarakat. Daging biji merupakan bagian yang paling banyak manfaatnya. Proses pemecahan kemiri dilakukan secara manual dan dengan menggunakan alat atau mesin. Adapun tujuan penelitian adalah untuk melakukan analisis efektifitas kemiri di kabupaten Solok di Sumatera Barat. Penelitian dilakukan dengan dua perlakukan yaitu dengan melakukan pembekuan bahan dan menyiram setelah dijemur dan menggunakan metoda pada umumnya. Parameter yang dievaluasi pada penelitian adalah sifat fisik kemiri, kapasitas kerja efektif, rendemen pemecahan, pengukuran kadar air, persentase kerusakan hasil, kecepatan putar alat, tingkat kebisingan alat. Kemampuan dari alat pemecah kemiri dengan bahan baku dibekukan sebesar 924,35 kg/jam, dengan rendemen sebesar didapat 35%. Persentase Hasil utuh yang paling baik yaitu pada kemiri dengan perlakuan pembekuan dalam freezer sebesar 83%. Hal ini dapat dijadikan acuan oleh petani kemiri dalam mengolah kemiri sebelum dipecah untuk mendapatkan hasil yang maksimal.Analysis of the Effectiveness of Candlenut Crackers in Solok Regency, West Sumatra Abstract. Candlenut is a plantation crop that has many benefits for the community. The flesh of the seed is the most beneficial part. The process of splitting hazelnut is done manually and by using a tool or machine. The research objective is to analyze the effectiveness of candlenut in Solok district, West Sumatra. The research was carried out with two treatments, namely by freezing the material and watering it after drying it and using the general method. Parameters observed in this study were the physical properties of candlenut, adequate working capacity, yield of solution, measurement of moisture content, percentage of yield damage, tool rotation speed, tool noise level. The work capacity obtained in hazelnut which was subjected to freezing treatment was 924.35 kg/hour. The highest yield was obtained from frozen hazelnut by 35%. The best percentage of intact yield was candlenut with freezing treatment in the freezer of 83%.