bluuebunny/crossref_metadata_2025_split huggingface dataset:
Body modifications in borderline personality disorder patients: prevalence rates, link with non-suicidal self-injury, and related psychopathology
Authors: Blay Martin , Hasler Roland , Nicastro Rosetta , Pham Eléonore , Weibel Sébastien , Debbané Martin , Perroud Nader 
Published: March 2023

Abstract
Background
Borderline Personality Disorder (BPD) is a potentially severe personality disorder, characterized by difficulties in emotion regulation and control of behaviors. It is often associated with non-suicidal self-injury (NSSI). Borderline personality features have also been linked to body modifications (BMs). However, the prevalence of BMs, the link between BMs and NSSI, and between BMs and several psychopathology dimensions (e.g. borderline severity, emotion regulation, impulsivity …) remains understudied in patients with BPD. This study aims to fill this gap, and to provide further evidence on the link between NSSI and BMs.

Methods
We used data from a psychiatric outpatient center located in Switzerland (n = 116), specialized in the assessment and treatment of BPD patients. Patients underwent several semi-structured interviews and self-report psychometric scales at the arrival, and the data were retrospectively analyzed.

Results
We found that 70.69% of the patients had one piercing or more, and 69.83% were tattooed. The total score of body modifications and the total number of piercings score of piercings were significantly positively associated with NSSI and the SCID BPD total score. The association with the SCID score was mainly driven by the “suicide and self-damaging behaviors” item and the “chronic feeling of emptiness” item. A significant association was found between total number of piercings and emotion dysregulation. On the other hand, the self-reported percentage of body covered by tattoos score was specifically associated with the sensation seeking subscale of the UPPS-P.

Conclusion
This study provides evidence on the prevalence of BMs in BPD patients, and on the link between BMs and NSSI in this population, suggesting a role of emotion regulation in the link between both constructs. These results also suggests that tattoos and piercings may be differentially linked to specific underlying psychological mechanisms. This calls for further considerations of body modifications in the assessment and care of BPD patients.
Heterogeneous rheology of Japan subduction zone revealed by postseismic deformation of the 2011 Tohoku-oki earthquake
Authors: Dhar Sambuddha , Muto Jun , Ohta Yusaku , Iinuma Takeshi 
Published: March 2023

AbstractThe 2011 Tohoku-oki earthquake produced the most well-recorded postseismic deformation of any megathrust earthquake in the world. Over the last decade, researchers have used a dense and widespread geodetic network of more than 1300 Global Navigation Satellite System (GNSS) stations inland, as well as the about 50 stations on the seafloor, to investigate the various deformation sources responsible for the observed crustal deformation. One of the contributing mechanisms to this crustal deformation is the stress relaxation of the viscoelastic mantle beneath the Japanese arc. As evident in experimental rock physics and geophysical observations, ambient mantle conditions and related rheology are expected to be heterogeneous in space. However, the contribution of such rheological heterogeneities to the postseismic deformation is still poorly understood. Here, we piece together several rheological heterogeneities inferred from the decade-long postseismic deformation of the 2011 Tohoku-oki earthquake. We reviewed more than twenty postseismic models to understand how viscoelastic earth can influence the postseismic surface deformation observed after the Tohoku-oki earthquake. Besides, we employed several synthetic models to tease out the contribution of individual rheological heterogeneities such as depth-dependent rheology of mantle wedge, oceanic asthenosphere, and low-viscosity zone beneath the volcanic front. We demonstrate that the vertical postseismic observation is the key to unravel rheological complexity beneath northeastern Japan. The broader vertical deformation pattern reveals the major viscosity contrast between backarc and forearc, and small-scale subsidence detects the presence of low-viscosity bodies related to arc magmatism. In short, this review paper provides a vista of three-dimensional heterogeneous rheology of viscoelastic earth. These rheological heterogeneities may play a crucial role in bridging the gap between our understanding of different phase of subduction zone earthquake cycle.
Adherence to anti-retroviral therapy, decisional conflicts, and health-related quality of life among treatment-naïve individuals living with HIV: a DEARS-J observational study
Authors: Sekine Yusuke , Kawaguchi Takashi , Kunimoto Yusuke , Masuda Junichi , Numata Ayako , Hirano Atsushi , Yagura Hiroki , Ishihara Masashi , Hikasa Shinichi , Tsukiji Mariko , Miyaji Tempei , Yamaguchi Takuhiro , Kinai Ei , Amano Kagehiro 
Published: March 2023

Abstract
Background
Supporting people living with HIV using anti-retroviral therapy (ART) is important due to the requirement for strict medication adherence. To date, no data from longitudinal studies evaluating adherence by treatment-naïve people living with HIV are currently available. We investigated the adherence of treatment-naïve people living with HIV over time and examined the relationships among decisional conflicts, adherence, and health-related quality of life (HRQL).

Methods
The survey items included adherence (visual analogue scale [VAS]), decisional conflict (decisional conflict scale [DCS]), and HRQL (Medical Outcomes Study HIV Health Survey [MOS-HIV]). The DCS and MOS-HIV scores and the VAS and MOS scores were collected electronically at the ART initiation time point and at 4-, 24-, and 48-week post-treatment time points.

Results
A total of 215 participants were enrolled. The mean DCS score was 27.3 (SD, 0.9); 23.3% of participants were in the high-score and 36.7% in the low-score groups. The mean adherence rates at 4, 24, and 48 weeks were 99.2% (standard error [SE], 0.2), 98.4% (SE, 0.4), and 96.0% (SE, 1.2), respectively. The least-square means of the MOS-HIV for the DCS (high vs. low scores) were 64.4 vs. 69.2 for general health perceptions and 57.7 vs. 64.0 for HRQL, respectively.

Conclusion
Adherence among treatment-naïve people living with HIV was maintained at a higher level, and HRQL tended to improve with ART. People with high levels of decisional conflict tended to have lower HRQL scores. Support for people living with HIV during ART initiation may be related to HRQL.
“My Body, My Rhythm, My Voice”: a community dance pilot intervention engaging breast cancer survivors in physical activity in a middle-income country
Authors: Rubio María Alejandra , Mejía-Arbeláez Carlos M. , Wilches-Mogollon Maria A. , Moreno Sergio , Finck Carolyn , Rosas Lisa G. , Romero Sol A. , Guevara Paula , Cabas Santiago , Rubiano Oscar , Flórez-Pregonero Alberto , León José G. , Alarcón Luis Fernando , Haile Robert , Sarmiento Olga L. , King Abby C. 
Published: March 2023

Abstract
Background
Interventions to promote physical activity among women breast cancer survivors (BCS) in low- to middle-income countries are limited. We assessed the acceptability and preliminary effectiveness of a theory-driven, group-based dance intervention for BCS delivered in Bogotá, Colombia.

Methods
We conducted a quasi-experimental study employing a mixed-methods approach to assess the 8-week, 3 times/week group dance intervention. The effect of the intervention on participants’ physical activity levels (measured by accelerometry), motivation to engage in physical activity, and quality of life were evaluated using generalized estimating equation analysis. The qualitative method included semi-structured interviews thematically analyzed to evaluate program acceptability.

Results
Sixty-four BCS were allocated to the intervention (n = 31) or the control groups (n = 33). In the intervention arm, 84% attended ≥ 60% of sessions. We found increases on average minutes of moderate-to-vigorous physical activity per day (intervention: +8.99 vs control: −3.7 min), and in ratings of motivation (intervention change score = 0.45, vs. control change score= −0.05). BCS reported improvements in perceived behavioral capabilities to be active, captured through the interviews.

Conclusions
The high attendance, behavioral changes, and successful delivery indicate the potential effectiveness, feasibility, and scalability of the intervention for BCS in Colombia.

Trial registration
ClinicalTrial.gov NCT05252780, registered on Dec 7th, 2021—retrospectively registered unique protocol ID: P20CA217199-9492018.
Adapted suicide safety plans to address self-harm, suicidal ideation, and suicide behaviours in autistic adults: protocol for a pilot randomised controlled trial
Authors: Rodgers Jacqui , Goodwin Jane , Nielsen Emma , Bhattarai Nawaraj , Heslop Phil , Kharatikoopaei Ehsan , O’Connor Rory C. , Ogundimu Emmanuel , Ramsay Sheena E. , Steele Katie , Townsend Ellen , Vale Luke , Walton Emily , Wilson Colin , Cassidy Sarah 
Published: March 2023

Abstract
Background
Suicide prevention is a national priority for the UK government. Autistic people are at greater risk of experiencing self-harm and suicidal thoughts and behaviours than the general population. Safety plans are widely used in suicide prevention but have not yet been designed with and for autistic people. We developed the first safety plan specifically targeting suicidality in autistic adults: the Autism Adapted Safety Plan (AASP). It consists of a prioritised list of hierarchical steps that can be used prior to or during a crisis to mitigate risk of self-harm and suicidal behaviour. This is a pilot study that aims to assess the feasibility and acceptability of the AASPs and the research processes, including the response rates, potential barriers and reach of AASPs, methods of recruitment, what comprises usual care, and economic evaluation methods/tools.

Methods
This is an external pilot randomised controlled trial of a suicide prevention tool aimed at mitigating the risk of self-harm and suicidal behaviour in autistic adults: AASPs. Participants will be assessed at baseline and followed up 1 month and 6 months later. Assessments include questions about self-harm, suicidality, service use, and their experience of the AASP/taking part in the study. Autistic adults who have a clinical autism diagnosis and self-reported history of self-harm, suicidal thoughts, or suicidal behaviours within the last 6 months will be invited to take part in the study. Informed consent will be obtained. Participants will be recruited via community and third sector services (including community settings, autism charities, and mental health charities). They may also “self-refer” into the study through social media recruitment and word of mouth. Ninety participants will be randomised to either develop an AASP or receive their usual care in a 1:1 ratio.

Discussion
The present study will provide an evaluation of the suitability of the processes that would be undertaken in a larger definitive study, including recruitment, randomisation, methods, questionnaires, outcome measures, treatment, and follow-up assessments.

Trial registration
ISRCTN70594445, Protocol v4: 8/2/22.
Impact of sexual intercourse on frozen-thawed embryo transfer outcomes: a randomized controlled trial
Authors: Hou Jin-Wei , Yuan Li-Hua , Cao Xian-Ling , Song Jing-Yan , Sun Zhen-Gao 
Published: March 2023

Abstract
Background
Exposure of the female reproductive tract to either seminal plasma or fluid component of the ejaculate is beneficial to achieving successful embryo implantation and normal embryo development. But whether the “physical” component of sexual intercourse during the peri-transfer period have any influence on frozen-thawed embryo transfer (FET) pregnancy outcomes is not clear.

Methods
We conducted a randomized trial that included 223 patients undergoing in vitro fertilization (IVF) treatment at a university-affiliated reproductive center from 19 July 2018 to 24 February 2019. Enrolled patients undergoing IVF treatment were randomized either to engage sexual intercourse using the barrier contraception (Group A, n = 116) or to abstain (Group B, n = 107) one night before FET. The primary outcome was clinical pregnancy rate.

Results
Patients having intercourse had higher clinical pregnancy rate (51.72% vs. 37.07%, P = 0.045) and implantation rate (38.31% vs. 24.77%, P = 0.005) compared to those did not engage intercourse. However, there was no significant difference of the spontaneous abortion rate between two groups (11.67% 33 vs. 14.63%, P = 0.662).

Conclusions
Sexual intercourse before embryo transfer may improve the clinical pregnancy and implantation rates during FET cycles. However, it should be noted that patients choose only one time for sexual intercourse, that is, the night before embryo transfer.

Trial registration
The present study was registered at the Chinese Clinical Trial Registry (http://www.chictr.org.cn/, ChiCTR1800017209).
Psychometric properties of the BALCI Turkish version
Authors: Mercan Oğuz , Kabadayı Fedai 
Published: March 2023

AbstractThe present study aimed to adapt and validate the Beliefs About Losing Control Inventory (BALCI) in the non-clinical Turkish emerging adults sample. The study group consisted of 549 participants from three study phases and aged between 18 and 28 years and mainly women. According to the results of the confirmatory factor analysis (CFA), the BALCI Turkish Version (BALCI-TV) confirmed 21 items in three factors. The network analysis findings showed that the items including the factors were together. The results indicated that configural, metric, scalar, and strict invariance across the gender. Cronbach’s α and McDonald’s ω of the total BALCI-TV were .90. Test–retest correlation result was .89. All results indicated that the BALCI-TV had good psychometric properties. The BALCI-TV can be provided to measure control and beliefs related to control within obsessive–compulsive disorder for Turkish academics and mental health practitioners.
Anatomical feasibility of an endovascular aortic arch repair with the NEXUS endograft in patients treated with a frozen elephant trunk procedure for aortic arch pathology
Authors: Exelmans Ward , Mufty Hozan , Maleux Geert , Verbrugghe Peter , Fourneau Inge 
Published: March 2023

Abstract
Background
The aim of this study was to evaluate the feasibility of an endovascular repair, using the NEXUS™ Aortic Arch Stent Graft System, in a real-world cohort of patients, treated with a Frozen Elephant Trunk (FET) procedure for pathology involving the aortic arch.

Results
The preoperative computed tomography angiography scans of 37 patients were retrospectively analyzed using a dedicated workstation. In total, seven patients (N = 7/37; 18.9%) were eligible for endovascular repair. This number increased to eleven patients (N = 11/37; 29.7%) if an additional relining of the distal aorta would be performed. Device suitability was 47.1% in patients (N = 8/17; 47.1%) with aortic arch aneurysm, 12.5% (N = 1/8; 12.5%) in patients with an acute Stanford type A dissection and 50% (N = 2/4; 50%) in patients with Crawford type II thoraco-abdominal aneurysm. The stent graft was not suitable for any of the two patients with chronic type B dissection (N = 0/2; 0%). In 22 patients (N = 22/37; 59.5%) an endovascular repair with this type of stent graft was not feasible due to an inadequate proximal sealing zone. There was no suitable brachiocephalic trunk landing zone in 13 patients (N = 13/37; 35.1%). There was no suitable distal landing zone distal in 14 patients (N = 14/37; 36.8%). This number decreased to ten patients (N = 10/37; 27.0%) when considering an additional relining of the distal aorta.

Conclusions
Endovascular repair with the NEXUS single branch stent graft is feasible in a minority of this real-world cohort that underwent a Frozen Elephant Trunk procedure. However, the applicability of this device probably improves in cases with isolated aortic arch aneurysms.
Genome editing in cotton: challenges and opportunities
Authors: Khan Zulqurnain , Khan Sultan Habibullah , Ahmed Aftab , Iqbal Muhammad Umar , Mubarik Muhammad Salman , Ghouri Muhammad Zubair , Ahmad Furqan , Yaseen Saba , Ali Zulfiqar , Khan Asif Ali , Azhar Muhammad Tehseen 
Published: March 2023

AbstractCotton has enormous economic potential providing high-quality protein, oil, and fibre. A large increase in cotton output is necessary due to the world's changing climate and constantly expanding human population. In the past, conventional breeding techniques were used to introduce genes into superior cotton cultivars to increase production and to improve quality. The disadvantages of traditional breeding techniques are their time-consuming, reliance on genetic differences that are already present, and considerable backcrossing. To accomplish goals in a short amount of time, contemporary plant breeding techniques, in particular modern genome editing technologies (GETs), can be used. Numerous crop improvement initiatives have made use of GETs, such as zinc-finger nucleases, transcription-activator-like effector nucleases, clustered regularly interspaced palindromic repeats (CRISPR), and CRISPR-associated proteins systems (CRISPR/Cas)-based technologies. The CRISPR/Cas system has a lot of potential because it combines three qualities that other GETs lack: simplicity, competence, and adaptability. The CRISPR/Cas mechanism can be used to improve cotton tolerance to biotic and abiotic stresses, alter gene expression, and stack genes for critical features with little possibility of segregation. The transgene clean strategy improves CRISPR acceptability addressing regulatory issues associated with the genetically modified organisms (GMOs). The research opportunities for using the CRISPR/Cas system to address biotic and abiotic stresses, fibre quality, plant architecture and blooming, epigenetic changes, and gene stacking for commercially significant traits are highlighted in this article. Furthermore, challenges to use of CRISPR technology in cotton and its potential for the future are covered in detail.
Cross-cultural study the macro variables and its impact on exchange rate regimes
Authors: Jamil Muhammad Naveed , Rasheed Abdul , Maqbool Adnan , Mukhtar Zeeshan 
Published: March 2023

AbstractThis is an empirical analysis of study simultaneously focus on examining the impact of macroeconomic variables, i.e., GDP growth, GDP per capita, inflation, foreign direct investment, exports, imports, interest rates, foreign debt and foreign reserves on the exchange rate regimes, using the sample of five countries from MSCI developed markets index, emerging markets index and frontier markets index each from 1970 to 2020. This study predicts and provides several essential contributions for markets, financial and economic, that fills the gaps in the markets economic and financial literacy of desired countries. The study identifies and evaluates the impact using the most advanced statistical frameworks. This study adopts ML—binary logit (quadratic hill climbing) and investigates the change in the exchange rate regimes due to macroeconomic variables. The empirical results confirm that Australia, Hong Kong, Japan, New Zealand and Singapore markets take timely correct exchange rate regimes decisions, which lead to developed markets. As emerging markets and frontier markets never adopt the exchange rate regimes three, four, and six, which is a significant impact factor that affects those markets never growth according develops markets. Foreign debts, inflation and foreign reserves are severe challenges for emerging and frontier markets.
Synthesis, biological activity of newly designed sulfonamide based indole derivative as anti-microbial agent
Authors: Agrawal Khushbu , Patel Tarun , Patel Rajeshree 
Published: March 2023

Abstract
Background
In medicinal chemistry, indole and its derivative play an important role. Indole is gaining a lot of importance in medicinal chemistry due to its physiological activity which includes anticancer, antitubercular, antimicrobial, antiviral, antimalarial, anti-inflammatory activities, antileishmanial agents, anti-cholinesterase, and enzyme inhibitory. The spread of antimicrobial resistance becomes a threat to both humans and animals. Antimicrobial resistance has been declared in the top 10 global major health risks by WHO including reported data of 2020 of AMR with 3,106,002 confirmed infections in humans across 70 countries.

Result
In this present work some new sulfonamide-based indole derivatives were synthesized by using 1H-indole -2 carboxylic acid as a starting material. The structure of all synthesized sulfonamide-based indole derivatives was confirmed by 1H NMR and LCMS Spectroscopy.

Conclusion
All the synthesized compounds were screened for anti-microbial activity against Gram Positive Staphylococcus aureus, Bacillus megaterium, and Gram Negative Klebsiella pneumonia, Escherichia coli, Salmonellatyphiae, Shigella sp., Enterobacter aerogenes. Among gram-positive Staphylococcus aureus, and Bacillus megaterium. The compound shows activity against Staphylococcus aureus, and among all gram-negative bacteria against Klebsiella pneumonia shows good activity.
Secondary cutaneous aspergillosis in a child with Behçet’s disease: a case-based update
Authors: Nachate Soumia , El Mouhtadi Mouad , Zouine Yousra , Haouane Mohamed Amine , Azami Mohamed Amine , Saiad Mohamed Oulad , Basraoui Dounia , Jalal Hicham , Nassih Houda , Elqadiry Rabiy , Bourrahouat Aicha , Sab Imane Ait , El Hakkouni Awatif 
Published: March 2023

Abstract
Background
Invasive aspergillosis (IA) is one of the rarest opportunistic fungal infections and has increased in frequency worldwide in recent years. It is a life-threatening infection associated with high mortality rates. Invasive pulmonary aspergillosis (IPA) is the most severe form of the disease. Extrapulmonary forms can develop as a primary infection or occur as part of a disseminated infection from the lung in severely immunocompromised patients. The major limitation in the management of these infections is the challenge of early diagnosis.

Case presentation
Here we report a case of secondary cutaneous aspergillosis that developed from extensive pulmonary aspergillosis in a 3-year-old female who underwent immunosuppressive therapy for a diagnosed Behçet disease (BD). Aspergillus hyphae were identified on skin biopsies. Cultures grew Aspergillus fumigatus. The diagnosis of cutaneous aspergillosis enabled us to diagnose IPA, although there was no mycopathological proof of lung infection. The patient was successfully treated with voriconazole (8 mg/kg/day) and surgical debridement of the skin lesion.

Conclusions
Although cutaneous involvement in aspergillosis is extremely uncommon, it may be the presenting feature in some cases, allowing for an accurate and timely diagnosis of deeply infected sites. Accordingly, when evaluating skin lesions in immunocompromised individuals, especially debilitated children with underlying diseases requiring long-term immunosuppressive agents, cutaneous aspergillosis should be vigilantly considered.