bluuebunny/crossref_metadata_2025_split huggingface dataset:
Combined intake of sugar‐sweetened beverages and sugar‐containing ultra‐processed foods is associated with an increase in body mass index during early childhood
Authors: Pereyra‐González Isabel , Mattei Josiemer 
Published: March 2023

SummaryBackgroundSugar‐containing ultra‐processed (SUP) foods and beverages consumption has increased globally in recent years and contributes to the rising global trends of obesity and diet‐related chronic non‐communicable diseases. However, there are limited longitudinal studies of SUP foods and beverages intake and weight gain in children.ObjectivesTo examine associations between intake of sugar‐sweetened beverages (SSB) and SUP foods and changes in body mass index during early childhood.MethodsMultistage sampling was used to select a nationally representative sample of Uruguayan children living in urban areas from the 2012–2013 Continuous Household Survey. The sample for this analysis included all children aged 0–3 years 11 months with dietary data in 2013–2014 (wave 1;n = 2611) and in 2015–2016 (wave 2;n = 2383). Multilevel regression modelling tested the association between children's consumption of SSB and SUP foods and change in BMIz‐score (BMIz).ResultsIn multivariable‐adjusted models, intake of SSB and SUP foods (in combination but not individually) in both waves was positively associated with change in BMIz over 2 yearsβcoefficient: 0.13 (95% confidence interval [CI]: 0.02, 0.23). BMIz decreased among non‐consumers (β: −0.12, 95% CI: −0.24, −0.00,p = 0.048). Associations were significant for SUP foods but not SSB foods individually. Children consuming ≥2 SSB and SUP foods (vs. <2) at baseline had increased BMIz (pfor trend = 0.02).ConclusionEarly and current intake of SSB and SUP foods and beverages was associated with increases in BMIz in children over 2 years.
Transvaginal vesicovaginal fistula closure: A retrospective study of 28 cases at a single facility in Japan
Authors: Kurokawa Ippei , Nomura Yukiko , Nakagawa Chie , Okada Yoshiyuki , Fuji Kohzo , Yoshimura Yasukuni 
Published: March 2023

ObjectivesWe aimed to report the background of patients with vesicovaginal fistulas (VVFs) at our center, which has treated a relatively large number of such patients in Japan, as well as the ingenuity and outcomes of vesicovaginal fistula closure (VVFC). We also investigated the causes of VVFs.MethodsA retrospective review was performed for 28 patients with VVFs treated at our center. Age, body mass index, etiology, site of fistula, and postoperative outcomes were investigated.ResultsTwenty‐one (75%) fistulas occurred following hysterectomy. The overall success rate of VVFC was 85.7%, and the success rate limited to the first attempt was 89.5%. In 68% of cases, no bladder injury suspected as the cause of VVF was noticed during the surgery. Energy devices were used in all 12 patients for whom information on the type of device used for hysterectomy was confirmed.ConclusionsTo our knowledge, this is the first report to evaluate a relatively large number of VVFCs in Japan. Although VVF is thought to be caused by bladder injury during hysterectomy, delayed thermal damage might also result in this pathology, even if there is no apparent intraoperative bladder injury.
Effect of superfine grinding on the physico‐chemical and antioxidant properties ofCistanche deserticolapowders
Authors: Hou Shoubu , Zhao Qing‐Sheng , Chang Senlin , Li Hang , Zha Sheng‐hua , Li Qiushuang , Weng Di , Qin Qiao , Zhao Bing , Zhang Jinyu 
Published: March 2023

AbstractCistanche deserticolahas recently been included in the category of food. In this study, the physical and chemical attributes and antioxidant capacity of six kinds ofC. deserticolapowders prepared by jet milling were discussed. With the decrease of particle size, the specific surface areas ofC. deserticolpowders had increased significantly (from 0.040 ± 0.0060 to 0.86 ± 0.030 m2·g−1). The repose angles and slide angles (from 18.43 ± 1.15° to 34.21 ± 1.72° and 27.38 ± 1.72° to 35.80 ± 1.49°, respectively), water and oil holding capacities (from 2.40 ± 0.11 to 1.23 ± 0.12 g/g, 0.73 ± 0.12 to 1.39 ± 0.11 g/g, respectively) of superfineC. deserticolapowders were compared with coarse powders. Superfine grinding promoted the dissolution of active substances, such as the dissolution of phenylethanol glycoside increased from 0.15% to 2.11%. The ultrafine powders ofC. deserticolashow great potential in food industry, such as health foods and dietary foods, extending the application ofC. deserticola.Practical ApplicationsCistanche deserticolahave recently been included into food catalogue and the ultrafine particles ofC. deserticolawould be widely used in food industry. Therefore, to understand the physico‐chemical and antioxidant properties are very necessary, which could be conducive to improve their application. The study showed that the ultrafine powders ofC. deserticolahave better physico‐chemical and antioxidant properties than coarse powders.
Identification of residues in the first transmembrane domain of the P2X7 that regulates receptor trafficking, sensitization, and dye uptake function
Authors: Rupert Marian , Bhattacharya Anirban , Sivcev Sonja , Knezu Michal , Cimicka Jana , Zemkova Hana 
Published: March 2023

AbstractP2X receptors (P2X1‐7) are trimeric ion channels activated by extracellular ATP. Each P2X subunit contains two transmembrane helices (TM1 and TM2). We substituted all residues in TM1 of rat P2X7 with alanine or leucine one by one, expressed mutants in HEK293T cells, and examined the pore permeability by recording both membrane currents and fluorescent dye uptake in response to agonist application. Alanine substitution of G27, K30, H34, Y40, F43, L45, M46, and D48 inhibited agonist‐stimulated membrane current and dye uptake, and all but one substitution, D48A, prevented surface expression. Mutation V41A partially reduced both membrane current and dye uptake, while W31A and A44L showed reduced dye uptake not accompanied by reduced membrane current. Mutations T28A, I29A, and L33A showed small changes in agonist sensitivity, but they had no or small impact on dye uptake function. Replacing charged residues with residues of the same charge (K30R, H34K, and D48E) rescued receptor function, while replacement with residues of opposite charge inhibited (K30E and H34E) or potentiated (D48K) receptor function. Prolonged stimulation with agonist‐induced current facilitation and a leftward shift in the dose–response curve in the P2X7 wild‐type and most functional mutants, but sensitization was absent in the W31A, L33A, and A44L. Detailed analysis of the decay of responses revealed two kinetically distinct mechanisms of P2X7 deactivation: fast represents agonist unbinding, and slow might represent resetting of the receptor to the resting closed state. These results indicate that conserved and receptor‐specific TM1 residues control surface expression of the P2X7 protein, non‐polar residues control receptor sensitization, and D48 regulates intrinsic channel properties.image
Implicit rationing of nursing care reported by nurses from different types of hospitals and hospital units
Authors: Zeleníková Renáta , Jarošová Darja , Polanská Andrea , Mynaříková Eva 
Published: March 2023

AbstractAims and ObjectivesThe study aimed to investigate differences in assessing implicit rationing of nursing care by Czech nurses with respect to the type of unit and type of hospital.BackgroundImplicit rationing of nursing care may differ across different types of hospitals and hospital units.DesignThis study used a multicentre cross‐sectional study design.MethodsThe STROBE checklist for observational cross‐sectional studies was followed for reporting of the research study. The sample included 8209 nurses providing direct care to medical and surgical patients in 14 acute care Czech hospitals. The main outcome was implicit rationing of nursing care as measured with a Czech version of the Perceived Implicit Rationing of Nursing Care (PIRNCA) instrument. Data were collected from September 2019 to October 2020.ResultsThe most frequently rationed nursing care activity was timely response to patient or family request/need, followed by emotional or psychological support and adequate supervision of delegated tasks. More implicitly rationed nursing care was reported in medical units. Statistical differences were found in rating 25 items and the PIRNCA total score. Nurses from middle‐sized hospitals reported implicitly rationed care more frequently than those from large hospitals.ConclusionMore rationed care was reported by nurses from medical units and nurses from middle‐sized hospitals. Organisational variables (the type of unit and type of hospital) influence the implicit rationing of nursing care in our study.Relevance to Clinical PracticeThe findings call for nursing managers to pay attention to organisational variables which may affect the implicit rationing of nursing care.
Moderate dietary salt restriction improves blood pressure and mental well‐being in patients with primary aldosteronism: The salt CONNtrol trial
Authors: Schneider Holger , Sarkis Anna‐Lina , Sturm Lisa , Britz Vera , Lechner Andreas , Potzel Anne L. , Müller Lisa Marie , Heinrich Daniel A. , Künzel Heike , Nowotny Hanna F. , Seiter Thomas Marchant , Kunz Sonja , Bidlingmaier Martin , Reincke Martin , Adolf Christian 
Published: March 2023

AbstractBackgroundPrimary aldosteronism (PA) is a frequent cause of hypertension. Aldosterone excess together with high dietary salt intake aggravates cardiovascular damage, despite guideline‐recommended mineralocorticoid receptor antagonist (MRA) treatment.ObjectivesTo investigate the antihypertensive impact of a moderate dietary salt restriction and associated physiological changes, including mental well‐being.MethodsA total of 41 patients with PA on a stable antihypertensive regimen—including MRA—followed a dietary salt restriction for 12 weeks with structured nutritional training and consolidation by a mobile health app. Salt intake and adherence were monitored every 4 weeks using 24‐h urinary sodium excretion and nutrition protocols. Body composition was assessed by bioimpedance analysis and mental well‐being by validated questionnaires.ResultsDietary salt intake significantly decreased from 9.1 to 5.2 g/d at the end of the study. In parallel, systolic (130 vs. 121 mm Hg) and diastolic blood pressure (BP) (84 vs. 81 mm Hg) improved significantly. Patients’ aptitude of estimating dietary salt content was refined significantly (underestimation by 2.4 vs. 1.4 g/d). Salt restriction entailed a significant weight loss of 1.4 kg, improvement in pulse pressure (46 vs. 40 mm Hg) and normalization of depressive symptoms (PHQD scale, p < 0.05). Salt restriction, cortisol after dexamethasone suppression test and dosage of renin‐angiotensin‐aldosterone‐system (RAAS) blockers were independently associated with BP reduction.ConclusionA moderate restriction of dietary salt intake in patients with PA substantially reduces BP and depressive symptoms. Moreover, the findings underline that a sufficient RAAS blockade seems to augment the effects of salt restriction on BP and cardiovascular risk.
Neural oscillations after acute large artery atherosclerotic cerebral infarction during resting state and sleep spindles
Authors: Zeng Guoli , Zhou Yan , Yang Yushu , Ruan Lili , Tan Linjie , Luo Hua , Ruan Jianghai 
Published: March 2023

SummaryElectroencephalogram‐microstate analysis was conducted using low‐resolution electromagnetic tomography (LORETA)‐KEY to evaluate dynamic brain network changes in patients with acute large artery atherosclerotic cerebral infarction (LAACI) during the rest and sleep stages. This study included 35 age‐ and sex‐matched healthy controls and 34 patients with acute LAACI. Each participant performed a 3‐h, 19‐channel video electroencephalogram test. Subsequently, 20 epochs of 2‐s sleep spindles during stage N2 sleep and five epochs of 10‐s electroencephalogram data in the resting state for each participant were obtained. In both the resting state and sleep spindles, patients with LAACI displayed altered neural oscillations. The parameters of microstate A (coverage, occurrence, and duration) increased during the resting state in the patients with LAACI compared with healthy controls. The coverage and occurrence of microstate B and D were reduced in the LAACI group compared with the healthy controls (p < 0.05). Moreover, during sleep spindles, the duration of microstate A and the transition probability from microstate A and B to C decreased, but the coverage of microstate B and the transition rate from microstate B to D increased (p < 0.05) in the LAACI group compared with the healthy controls. These results enable better understanding of how neural oscillations are modified in patients with LAACI during the resting state and sleep spindles. Following LAACI, the dynamic brain network undergoes changes during sleep spindles and the resting state. Continued long‐term investigations are required to determine how well these changes in brain dynamics reflect the clinical characteristics of patients with LAACI.
The efficacy of intensive sleep retraining for insomnia: A systematic review and research agenda
Authors: Scott Hannah , Bensen‐Boakes Darah‐Bree , Lovato Nicole , Reynolds Amy , Perlis Michael , Lack Leon 
Published: March 2023

SummaryIntensive sleep retraining (ISR) is a brief behavioural treatment for sleep onset insomnia, administered in just a single overnight treatment session. This systematic review evaluates existing trials about the efficacy of intensive sleep retraining for treating insomnia, to inform whether there is enough evidence to recommend its use for clinical practice. A systematic literature search was conducted across three databases, yielding 108 results. Of these studies, three were deemed suitable for inclusion in this review. The included studies consistently reported significant reductions in insomnia symptoms following intensive sleep retraining, particularly decreases in sleep diary‐derived sleep latency and increases in total sleep time. Based on these inconclusive but promising findings, a research agenda is proffered to test intensive sleep retraining as a treatment for insomnia. Large randomised controlled trials are needed to elucidate the potential benefits of intensive sleep retraining for different populations with insomnia, as are mechanistic trials to test which components underlie its seemingly therapeutic effects. Since more practical modalities of intensive sleep retraining administration have been developed, such trials are more feasible to conduct now than ever before.
Effects of glutenin and gliadin on the surface tackiness of frozen cooked noodles
Authors: Wang Yuan‐Hui , Zhang Ya‐Ru , Qiao Lin , Guo Wei‐Min , Yang Yue‐Ying , Xu Fei 
Published: March 2023

AbstractThe mechanism of glutenin and gliadin on the surface tackiness of recooked frozen cooked noodles (FCNs) is unclear. In this study, the effects of glutenin and gliadin addition on the surface tackiness of FCNs were investigated. The addition of glutenin and gliadin reduced the surface tackiness (3.60 and 3.50 N) of recooked FCNs stored for 0 min. The addition of glutenin increased the rigidity of the gluten network and the compactness of FCNs and made the FCNs have a moisture‐distribution with multilayers. The addition of gliadin increased the tensile distance of FCNs, restricted water migration during frozen storage, and increased the membranous structure of the gluten network to wrap starch particles. Glutenin had a stronger effect on reducing the surface tackiness of FCNs than gliadin. In the future, the synergistic effects of different proportions of glutenin and gliadin on the gluten network of FCNs could be further studied.
Distrusted Partnership: Unpacking Anti‐Americanism in Turkey
Authors: Grigoriadis Ioannis N. , Aras Ümit Erol 
Published: March 2023

AbstractThe decline of US‐Turkey relations has been one of the most striking developments within NATO and the broader Western alliance. This article sheds light on this distrusted partnership by studying anti‐American sentiment in Turkish public opinion since the Arab uprisings of the 2010s. Employing a typology of anti‐Americanisms introduced by Keohane and Katzenstein, it examines views of the United States and US‐Turkey relations in the Turkish media and among the public, and it explores the conditions under which the declining relations could be reset. In particular, it shows how the ruling Justice and Development Party exploits anti‐US opinion, the Turkish media's role, the stances of Turkish opposition groups, and the long‐term consequences for the strained bilateral relationship.
Cooperative control of a platoon of connected autonomous vehicles and unconnected human‐driven vehicles
Authors: Zhou Anye , Peeta Srinivas , Wang Jian 
Published: March 2023

AbstractBy using kinematic state information obtained through vehicle‐to‐vehicle communications, connected autonomous vehicles (CAVs) can drive cooperatively to alleviate shockwave propagation associated with traffic disturbances. However, during the transition to full autonomy, CAVs and human‐driven vehicles (HDVs) will coexist on the road, creating mixed‐flow traffic. The inherent heterogeneity and randomness in human driving behavior can generate additional disturbances in the traffic flow. Further, HDVs without communication functionality (unconnected HDVs) can cause the control performance of CAVs to degrade by negatively impacting platoon formation. To proactively mitigate the negative impacts of HDVs in mixed‐flow traffic, this study proposes a cooperative control strategy with three components for platoons consisting of CAVs and unconnected HDVs: (i) a number estimator for estimating the number of HDVs between two CAVs, (ii) a kinematic state predictor for predicting the kinematic states of HDVs, and (iii) a multi‐anticipative car‐following controller (i.e., control strategy using kinematic state information of multiple preceding vehicles) for CAVs to maintain string stability and desired time headway. To initialize the proposed strategy, the number estimator is developed using a deep neural network (DNN). Then, a DNN‐based kinematic state predictor predicts the kinematic states of HDVs for CAVs to enable multi‐anticipative car‐following control. The multi‐anticipative car‐following controller is implemented using an extended intelligent driver model‐guided deep deterministic policy gradient algorithm, which ensures safety, string stability, and traffic efficiency. The effectiveness of the proposed control strategy is validated through numerical experiments using NGSIM data. Results indicate that the proposed strategy can produce accurate estimations of the number and the kinematic states of HDVs between CAVs. Further, it can achieve string stability while maintaining smaller time headways, compared to car‐following models used for training guidance under different market penetration rates of CAVs, which significantly improves traffic smoothness and mobility.
Errors to avoid when searching for studies for systematic reviews: A guide for nurse researchers
Authors: Briscoe Simon 
Published: March 2023

AbstractSystematic reviews aim to provide reliable answers to research questions by identifying and synthesising the available evidence using rigorous methods. This makes systematic reviews a cornerstone of evidence‐based practice in healthcare settings. However, despite the avowed aim and importance of systematic reviews, studies have shown that they often include serious flaws, including in the search for studies. In this article, some commonly seen errors in systematic review search strategies are described with the intention of alerting nurse researchers who are planning a systematic review to what should be avoided. These include errors relating to bibliographic databases and supplementary searches, including database selection, free‐text searching, controlled vocabulary and structural errors. The paper is framed within the context of older people nursing but has relevance to nurse researchers more widely.
Pacing maneuvers from the aortic cusps: A useful technique during ablation of focal arrhythmias arising from the aortic root
Authors: Toniolo Mauro , Taurian Marco , Rebellato Luca , Daleffe Elisabetta , Muser Daniele 
Published: March 2023

AbstractBackgroundThe ablation of arrhythmias arising near the His‐bundle region in the non‐coronary aortic cusp (NCAC) is challenging. Among the aortic sinuses of Valsalva, the NCAC is located between the right atrium and the left atrium. For this reason, pacing from the NCAC should result in atrial capture while pacing from the right and left coronary cusps (LCC) may result in ventricular capture. The objective of this study is to prove that atrial capture during pacing from the sinuses of Valsalva may be used to confirm a correct position in the non‐coronary cusp.MethodsA total of 30 patients with structurally normal heart undergoing left sided ablation procedures, underwent electrophysiological study of the aortic cusps. Each of the aortic valve cusps was paced with increasing outputs and analyzed offline to determine their unique electrocardiographic characteristics.ResultsIn the NCAC, we obtained an atrial capture in 29 out of 30 patients (96.6%). The atrial capture was highly specific for a position in the NCAC (p < .001). The median output required to capture from the cusp was 10 mA (range 5–25 mA) at a pulse width of 2 ms. In the right coronary cusp (RCC) and LCC, we obtained ventricular capture in all patients (100%). The median output required to capture from the cusp was 10 mA (range 10–25 mA) in RCC and 25 mA (range 10–25 mA) in LCC at a pulse width of 2 ms.ConclusionsAtrial capture during a pacemapping from the aortic cusps can be considered proof of a correct position in NCAC.
Saliency affects attentional capture and suppression of abrupt‐onset and color singleton distractors: Evidence from event‐related potential studies
Authors: Chen Xiaowen , Xu Bing , Chen Yanzhang , Zeng Xianqing , Zhang Yue , Fu Shimin 
Published: March 2023

AbstractAttention is the process of selecting relevant information and suppressing irrelevant information. However, it is still controversial whether attentional capture by salient but task‐irrelevant stimuli operates in a bottom‐up fashion (stimulus‐driven theory) or a top‐down fashion (goal‐driven theory) or if even salient distractors can be suppressed before capturing attention (signal suppression theory). In the present study, we investigated how saliency affects attentional capture (indexed by N2‐posterior‐contralateral [N2pc]) and suppression (indexed by distractor positivity [PD]) of abrupt‐onset and color singleton distractors in a visual search task. Experiment 1 showed that an abrupt‐onset distractor elicited both N2pc and PD, while a color singleton distractor elicited only PD. Moreover, the abrupt‐onset distractor elicited a larger N2pc and a larger PD relative to the color singleton distractor. In addition, both distractors elicited an early positive component, the positivity posterior contralateral (Ppc), which was also larger for abrupt onsets than for color singletons. Experiment 2 further demonstrated that when both the abrupt onset and color singleton were designed as targets, and thus required no attentional suppression, Ppc was elicited, but PD was not. This corroborated the finding in Experiment 1 that the later PD, not the early Ppc, reflected attentional suppression. Therefore, a more salient distractor demonstrates stronger early perceptual processing, can capture attention better and needs more attentional resources to be suppressed later. Based on these results, a three‐stage hypothesis is proposed, in which the saliency of a distractor modulates processing at early perception, attentional capture, and suppression stages.