bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of the Application Effect of an Emergency Caesarean Section Rapid Response Team with PDCA Cycle Management
Authors: Li Yi , Yang Dong , Yang Chunfen , Yang Shuangjian , Lan Hui 
Published: May 2023

Abstract
Objective To explore the clinical effect of constructing Rapid Response Team(RRT) with Plan-do-check-action (PDCA) Cycle Management in emergency caesarean section.Methods The patients who underwent routine emergency caesarean section were retrospectively analysed and divided into experimental group (51 patients with RRT) and control group (52 patients without RRT). Operation time related indexes, DDI passing rate, neonatal Apgar score and maternal complications were compared between the two groups.Results The DDI, DII, DOI and O-I of the experimental group were shorter than control group (P < 0.05). The experimental group’s DDI pass rate was higher than control group (P < 0.01). The 1-minute Apgar score of the experimental group was higher than control group (P < 0.05).Conclusion In the face of emergency situations, the RRT through PDCA cycle model may be more conducive to maternal and infant safety than conventional models.
Combining ability and Gene action studies for yield and fibre characters in Gossypium arboreum using Griffings numerical and Haymans graphical approach
Authors: Bhimireddy Sukrutha , S Rajeswari , N Premalatha , N Manikanda Boopathi , K Thirukumaran , A Manivannan 
Published: May 2023

Abstract
Background: For the purpose of utilising hybrid vigour to produce possible hybrids with a suitable level of stability, knowledge of gene activity and combining ability is a crucial prerequisite before choosing desirable parents.
Results: The present study was carried out with six parents and were crossed in full diallel fashion and generated 30 F1 hybrids. These hybrids were evaluated in two replications in Randomised Block Design at Department of Cotton, TNAU for combining ability and gene action. Diallel analysis was carried out according to Griffing’s method-I (parents+ F1+reciprocals) and model-I and Hayman’s graphical approach by using INDOSTAT software. Analysis of variance for combining ability indicated that mean square values of GCA, SCA and reciprocals were highly significant for all the traits except for uniformity index. RG763 and K12 showed highly positively significant GCA effects for most of the yield characters whereas PA838 and K12 for fibre quality traits and thus found as best general combiners. PAIG379×K12 and PDB29×K12 for yield traits and PDB29×PA838, RG763×PA838 and CNA1007× RG763 cross combinations for fibre quality traits can be recommended for future breeding programmes.
Conclusion: The results of both Griffing’s and Hayman’s approach showed that non-additive gene action predominates as SCA variance was bigger than variance, so heterosis breeding is thought to be the more fruitful option for enhancing many traits GCA.
Precise detection of IgG molecules using AuNP anchored, PEDOT-MoS 2 based electrochemical sensor
Authors: Medhi Ankush , MOHANTA Dambarudhar 
Published: May 2023

Abstract

We report on gold nanoparticle (AuNP) anchored PEDOT-MoS2 based immunosensor probes for rapid electrochemical detection of the specific antigen. After structural and morphological characterization, the AuNP/PEDOT-MoS2 composite electrodes were subjected to Cyclic voltammetry (CV) and impedance spectroscopy (EIS) studies. The electroactivity and interfacial charge transfer kinetics of the electrodes were exploited in 0.1 M phosphate buffer solution (PBS) containing 5 mM K3[Fe(CN)6] as redox probe. Further, the immunosensor was developed considering cross linking of glutaraldehyde over AuNP/PEDOT-MoS2 electrode. Monitored by electrochemical means, an observable rise in current trend upon detection of specific antigen was believed to be due to suitable interfacial changes of the bioelectrode under study. Differential pulse voltammetry (DPV) technique provided the sensing parameters with the help of the calibration equation. It is observed that the antibody-antigen interaction taking place in our system follows Langmuir adsorption isotherm with the adsorption coefficient value, 27.5 L/g. The limit of detection (LOD) and sensitivity of the as prepared immuno-responsive biosensor was estimated to be 81.46 pM and 1.8456 (µA/(ng/mL) cm2) respectively under a wide linear range of 7.7-263 ng/mL.
Care-seeking behavior, perceived professional healthcare support, social structural and perinatal mental health: a cross-sectional study from the perspective of Chinese mother
Authors: An Shanshan , Sun Sheng 
Published: May 2023

Abstract
Background Perinatal mental health (PMH) represents a public health concern due to their impact on the health of mothers and their infants. However, only a small proportion of Chinese mother seek help, and even when perinatal health services are available, mother 's PMH has not improved due to many factors. This study to determine the factors affecting the relationship between care-seeking behavior and PMH, to discover Chinese mother’s attitudes of care-seeking behavior. Understanding mother’s care-seeking behaviors is critical to devising strategies that increase treatment rates for perinatal mental health.Methods In this cross-sectional survey, face-to-face interviews were conducted among 1705 mother from early, middle, and late stages of pregnancy in hospitals with an annual delivery volume of at least 5000 in Wuxi during October 2021 to November 2022. Mother’s social demographic information and their different seeking healthcare were collected, also investigated the relationship between care-seeking behavior and PMH, as well as the multiple mediating effects of perceived professional healthcare support (PPHS) and perceived societal stigma or trust. Statistical analyses were performed using IBM SPSS 24.0 and AMOS 24.0, and the mediating effect was evaluated by bootstrapping with 95% confidence intervals (CI).Results Among 1705 mothers, 636 (37.3%) sought help from professional, and care-seeking behavior during early pregnancy is easier compared to later stages of pregnancy.However, even mother seeking help from professional, did not positively affect their PMH compared to mother who did not seek help, while reporting the PPHS, social stigma and trust with medical play multiple mediating roles in the relationship between care-seeking behavior and PMH. The perception of PPHS based on the trust or stigma of the medical system may reflect inadequacy surrounding that maternity care services and health education in China, further exploration in future research.Conclusion This study highlights the several barriers and facilitators at individual, institutional, doctor-patient relationship, and public policy levels that can affect relationship between mother’s care-seeking behavior and PMH. To effectively address this influence, it is imperative to recognise the need to develop interventions across socio-ecological levels is key.
Unraveling the Phase Diagram-Ion Transport Relationship in Aqueous Electrolyte Solutions and Correlating Conductivity with Concentration and Temperature by Semi-Empirical Modeling
Authors: Abu-Lebdeh Yaser , Al-Salih Hilal , Baranova Elena A. 
Published: May 2023

Abstract
The relationship between structure and ion transport in liquid electrolyte solutions is not well understood over the whole concentration and temperature ranges. In this work, we have studied the ionic conductivity (κ) as a function of molar ratio (x) and Temperature (T) for aqueous solutions of salts with nitrate anion and different cations (proton, lithium, calcium, and ammonium) along with their liquid-solid phase diagrams. The connection between the known structural changes in the phase diagrams and the ionic conductivity isotherms is established with an insight on the conductivity mechanism. Also, known isothermal (κ vs. x) and iso-compositional (κ vs. T) equations along with a newly proposed two variables semi-empirical model (κ = f (x, T)) were fitted to the collected data to validate their accuracy. The role of activation energy in controlling ionic conductivity is discussed. This work brings us closer to the development of a phenomenological model to describe the structure and transport in liquid electrolyte solutions.
Identification of potential biological processes and key genes in diabetes-related stroke through Weighted gene co-expression network analysis
Authors: He Yong , Bai Yang , Huang Qin , Feng Jie 
Published: May 2023

Abstract
Background Diabetes mellitus (DM) is an established risk factor for acute ischemic stroke (AIS). Although there are reports on the correlation of diabetes and stroke, data on its pathogenesis is limited. This study aimed to explore the underlying biological mechanisms and promising intervention targets of diabetes-related stroke.Methods Diabetes-related datasets (GSE38642 and GSE44035) and stroke-related datasets (GSE16561 and GSE22255) were obtained from the Gene Expression omnibus (GEO) database. The key modules for stroke and diabetes were identified by weight gene co-expression network analysis (WGCNA). Gene Ontology (GO) and Kyoto Encyclopedia of Genes Genomes (KEGG) analyses were employed in the key module. Genes in stroke- and diabetes-related key modules were intersected to obtain common genes for DM-related stroke. In order to discover the key genes in DM-related stroke, the Cytoscape and protein-protein interaction (PPI) network were constructed. The key genes were functionally annotated in the Reactome database.Results By intersecting the diabetes- and stroke-related crucial modules, 24 common genes for DM-related stroke were identified. Metascape showed that neutrophil extracellular trap formation was primarily enriched. The hub gene was granulin precursor (GRN), which had the highest connectivity among the common genes. In addition, functional enrichment analysis indicated that GRN was involved in neutrophil degranulation, thus regulating neutrophil extracellular trap formation.Conclusions This study firstly revealed that neutrophil extracellular trap formation may represent the common biological processes of diabetes and stroke, and GRN may be potential intervention targets for DM-related stroke.
Association between systemic inflammatory response index and left ventricular remodeling and systolic dysfunction in atrial fibrillation patients
Authors: Chi Runze , Shan Xiaoli , Guan Chunping , Yang Hao , Wang Xiangkun , Li Bingong , Zhang Qing 
Published: May 2023

Abstract
Background:
Cardiac remodeling and dysfunction can be caused by atrial fibrillation (AF). The aim of this research is to investigate the relationship between the systemic inflammatory response index (SIRI) and left ventricular (LV) remodeling and systolic function in individuals with AF.
Methods:
416 patients with AF who were admitted to the Second Department of Cardiology in the East Ward of the Qingdao Municipal Hospital between January 2020 and May 2022 were included in the present retrospective research. The relationship between SIRI and various cardiac parameters was analyzed. The patients' left atrial (LA) enlargement and left ventricular (LV) hypertrophy and systolic dysfunction were evaluated.
Results:
SIRI significantly correlated with LV end-diastolic diameter (LVDd), LV posterior wall thickness at end-diastole (LVPWTd), interventricular septal thickness at end-diastole (IVSTd), LV mass index (LVMI), LV ejection fraction (LVEF), LA diameter (LAD), C-reactive protein (CRP), and N-terminal pro-B-type natriuretic peptide (NT-proBNP) in patients with AF. In multivariate linear regression analyses, SIRI was discovered to be significantly related to LVMI (LN transferred) (p=0.025), LVEF (LN transferred) (p=0.005), and LAD (LN transferred) (p=0.007). In multivariate logistic regression, the highest quartile of SIRI (SIRI > 1.62 mg/L) was significantly associated with LV hypertrophy (p=0.026), impaired LV systolic function (p=0.002), and LA enlargement (p=0.025).
Conclusions:
SIRI was significantly associated with LV remodeling and systolic function impairment in patients with AF. SIRI may serve as a reliable and convenient inflammatory biomarker for detecting impaired cardiac structure and systolic function in patients with AF.
Three new species of genus Amanita Pers. (Amanitaceae) from India
Authors: Ghosh Aniket , Kumar Anil , Mehmood Tahir , Verma Komal , Chakraborty Dyutiparna , Hembrom Manoj Emanuel , Sharma Yash Pal 
Published: May 2023

Abstract
Based on morphological evidence and DNA sequencing, we propose three new species of the genus Amanita, namely Amanita aurantialba, A. indovaginata and A. pseudohemibapha from India. Amanita aurantialba, a member of sect. Phalloideae, A. indovaginata a representative of sect. Vaginatae and A. pseudohemibaphabelong to sect. Caesareae. Amanita aurantialba was collected from the temperate forests dominated by Quercus species, whereas A. pseudohemibapha and A. indovaginata are associated with tropical forests dominated by Shorea robusta. Photographs, line drawings and detailed morphological descriptions for these species are provided with comparisons against closely-related taxa.
Anti-Leishmania spp. antibody detection in domestic cats from a visceral leishmaniasis transmission area
Authors: Hartmann Gabriela , Roman Isac Junior , Lorenzetti Douglas Miotto , Herbichi Alana Pivoto , Mazaro Renata Dalcol , Santos Matheus Yuri dos , Tonin Alexandre Alberto , Vogel Fernanda Silveira Flôres , Fighera Rafael Almeida 
Published: May 2023

Abstract

Feline leishmanial infection is reported worldwide, but the epidemiological role of domestic cats in the leishmaniasis cycle remains unclear, and cats might act as cryptic reservoir hosts in endemic areas with no feline leishmaniosis cases. Considering that, a serological screening for anti-Leishmania spp. antibodies was performed by indirect immunofluorescence antibody test (IFAT) in 389 necropsied cats’ serum samples from a new visceral leishmaniasis transmission area with no feline leishmanial infection reported to unveil if the cats are being exposed to the parasite. The overall seroprevalence for Leishmania spp. was 11,05% (43/389). Statistical significance was not found between sex, neutering status, age group, breed, coat length, feline immunodeficiency virus (FIV) infection, and Leishmania spp. antibody detection. A positive association was found with coat color (cats within the orange spectrum with white [particolor]) with p = 0.044 and OR = 2.47 (1–6.13) and a negative association, with p = 0.01 and OR = 0.38 (0.18–0.79), between feline leukemia virus (FeLV) infection and IFAT positivity for Leishmania spp. Henceforth, parasite DNA detection by molecular studies is required to determine if it's exposition or infection.
Partial stability criteria for time-varying nonlinear systems
Authors: Hamzaoui Abdelfettah , Taieb Nizar Hadj , Hammami Mohamed Ali 
Published: May 2023

Abstract

In this paper we investigate the practical partial asymptotic and exponential stabilityof time-varying nonlinear systems. We derive some sufficient conditions that guaranteepractical partial stability of a large class of perturbed systems using Lyapunov’s theorywhere a converse theorem is presented. Therefore, we generalized some works which arealready made in the literature. Furthermore, some examples are presented.
2000 Mathematics Subject Classification: 34D20, 37B25, 37B55.
Defining critical illness using immunological endotypes in patients with and without of sepsis: A cohort study
Authors: Balch Jeremy A. , Chen Uan-I , Liesenfeld Oliver , Starostik Petr , Loftus Tyler J. , Efron Philip A. , Brakenridge Scott C. , Sweeney Timothy E. , Moldawer Lyle L. 
Published: May 2023

Abstract
Background: Sepsis is a heterogenous syndrome with limited therapeutic options. Identifying characteristic gene expression patterns, or endotypes, in septic patients may lead to targeted interventions. We investigated whether patients admitted to a surgical ICU with sepsis and with high risk of mortality express similar endotypes to non-septic, but still critically ill patients using two multiplex transcriptomic metrics obtained both on admission to a surgical intensive care unit (ICU) and at set intervals.
Methods: We analyzed transcriptomic data from 522 patients in two single-site, prospective, observational cohorts admitted to surgical ICUs over a 5-year period ending in July 2020. Using an FDA-cleared analytical platform (nCounter FLEX®, NanoString, Inc.), we assessed a previously validated 29-messenger RNA transcriptomic classifier for likelihood of 30-day mortality (IMX-SEV-3) and a 33-messenger RNA transcriptomic endotype classifier. Clinical outcomes included all-cause (in-hospital, 30-, 90-day) mortality, development of chronic critical illness (CCI), and secondary infections. Univariate and multivariate analyses were performed to assess for true effect and confounding.
Results: Sepsis was associated with a significantly higher predicted and actual hospital mortality. At enrollment, the predominant endotype for both septic and non-septic patients was adaptive, though with significantly different distributions. Inflammopathic and coagulopathic septic patients, as well as inflammopathic non-septic patients, showed significantly higher frequencies of secondary infections compared to those with adaptive endotypes (p<0.01). Endotypes changed during ICU hospitalization in 57.5% of patients. Patients who remained adaptive had overall better prognosis, while those who remained inflammopathic or coagulopathic had worse overall outcomes. For severity metrics, patients admitted with sepsis and a high predicted likelihood of mortality showed an inflammopathic (49.6%) endotype and had higher rates of cumulative adverse outcomes (67.4%). Patients at low mortality risk, whether septic or non-septic, almost uniformly presented with an adaptive endotype (100% and 93.4%, respectively).
Conclusion: Critically ill surgical patients express different and evolving immunological endotypes depending upon both their sepsis status and severity of their clinical course. Future studies will elucidate whether endotyping critically ill, septic patients can identify individuals for targeted therapeutic interventions to improve patient management and outcomes.
Supraphysiologic doses of 17β-Estradiol aggravate depression-like behaviors in ovariectomized mice possibly via regulating microglial responses and brain glycerophospholipid metabolism
Authors: Li Ming , Zhang Jing , Chen Wendi , Liu Shuang , Liu Xin , Ning Yunna , Cao Yongzhi , Zhao Yueran 
Published: May 2023

Abstract
Background 17β-Estradiol (E2) is generally considered neuroprotective in humans. However, the current clinical use of estrogen replacement therapy (ERT) is based on the physiological dose of E2 to treat menopausal syndrome and has limited therapeutic efficacy. The efficacy and potential toxicity of superphysiological doses of ERT for menopausal neurodegeneration are unknown.
Methods In this study, we investigated the effect of E2 with a supraphysiologic dose (0.5 mg/kg, sE2) on the treatment of menopausal mouse models established by ovariectomy. We performed the open field, Y-maze spontaneous alternation, forced swim tests, and sucrose preference test to investigate behavioral alterations. Subsequently, the status of microglia and neurons was detected by immunohistochemistry, HE staining, and Nissl staining, respectively. Real-time PCR was used to detect neuroinflammatory cytokines in the hippocampus and cerebral cortex. Using mass spectrometry proteomics platform and LC-MS/ MS-based metabolomics platform, proteins and metabolites in brain tissues were extracted and analyzed. BV2 and HT22 cell lines and primary neurons and microglia were used to explore the underlying molecular mechanisms in vitro.
Results sE2 aggravated depression-like behavior in ovariectomized mice, caused microglia response, and increased proinflammatory cytokines in the cerebral cortex and hippocampus, as well as neuronal damage and glycerophospholipid metabolismimbalance. Subsequently, we demonstrated that sE2 induced the pro-inflammatory phenotype of microglia through ERα/NF-κB signaling pathway and downregulated the expression of cannabinoid receptor 1 in neuronal cells, which were important in the pathogenesis of depression.
Conclusion These data suggest that sE2 may be nonhelpful or even detrimental to menopause-related depression, at least partly, by regulating microglial responses and glycerophospholipid metabolism.
Chip-Integrated Metasurface Full-Stokes Polarimetric Imaging Sensor
Authors: Yao Yu , Zuo Jiawei , Bai Jing , Choi Shinhyuk , Basiri Ali , Chen Xiahui , Wang Chao 
Published: May 2023

Abstract
Polarimetric imaging has a wide range of applications for uncovering features invisible to human eyes and conventional imaging sensors. Compact, fast, cost-effective and accurate full-Stokes polarimetric imaging sensors are highly desirable in many applications, which, however, remain elusive due to fundamental material limitations. Here we present a Metasurface-based Full-Stokes Polarimetric Imaging sensor (MetaPolarIm) realized by integrating an ultrathin (~600 nm) metasurface polarization filter array (MPFA) onto a visible imaging sensor with CMOS compatible fabrication processes. The MPFA is featured with broadband dielectric-metal hybrid chiral metasurfaces and double-layer nanograting polarizers. This chip-integrated polarimetric imaging sensor enables single-shot full-Stokes imaging (speed limited by the CMOS imager) with the most compact form factor, record high measurement accuracy, dual-color operation (green and red) and a full angle of view up to 40 degrees. MetaPolarIm holds great promise to enable transformative applications in autonomous vision, industry inspection, space exploration, medical imaging and diagnosis.
Adaptive Spectral Solution Method for Fredholm Integral Equations of the second kind
Authors: Abdennebi Issam , Rahmoune Azedine 
Published: May 2023

Abstract
The purpose of this paper is to develop and analyse an adaptive collocation method for Fredholm integral equations of the second kind, even if the equation exhibits a localized rapid variations, steep gradients, or steep front. The strategy of the adaptive procedure is to transform the given equation into an equivalent one with a sufficiently smooth behavior in order to ensure the convergence of the Legendre spectral collocation method without dividing the domain of the integral equation, as usual, into the sub intervals. Furthermore, the existence and uniqueness of the solution are discussed. Error analysis is carried out in both L∞-norm and L2-norm. Finally, several numerical examples are provided to show that the proposed method is preferable to its classical predecessor and some other existing approaches.