bluuebunny/crossref_metadata_2025_split huggingface dataset:
An emerging youth‐centered model of community resilience in communities impacted by gun violence: Power through Black Community and Unity
Authors: Grant Nickholas , Neville Helen , Ogunfemi Nimot , Smith Abisola , Groth Sara , Rodriguez Nino 
Published: January 2023

AbstractStudies commonly examine resilience as an outcome by way of measuring the degree to which protective factors maintain individuals' well‐being despite the presence of significant risk. In this study, we developed a model of community resilience that centered the voices of Black youth. Using data collected as part of a 3‐year, youth participatory action research project, we developed a model that focuses on what 11 Black youth perceive and believe contributes to community resilience through their investigation of problems and solutions related to community gun violence. Findings from a constructivist grounded theory analysis of multiple data sources (e.g., field notes, transcribed group discussions, youth photovoice activities) revealed our developing model of community resilience: Power through Black Community and Unity. Specifically, Power through Black Community and Unity was a core category that reflected the importance of care, support, and safety as strengths in the community's current response and resilience to gun violence, and future aspects the community could develop to increase community resilience to gun violence. This core category emerged in three subsequent ways: Collective Care, “Seeing Beyond the Bad,” and Supportive Teen Spaces. This study illustrates potential pathways that youth service agencies and community practitioners can consider enhancing in their programming to promote resilience in their communities.
Self‐Assembled Surfactant‐Polyoxovanadate Soft Materials as Tuneable Vanadium Oxide Cathode Precursors for Lithium‐Ion Batteries
Authors: McNulty Rory C. , Penston Keir , Amin Sharad S. , Stal Sandro , Lee Jie Yie , Samperi Mario , Pérez‐García Lluïsa , Cameron Jamie M. , Johnson Lee R. , Amabilino David B. , Newton Graham N. 
Published: January 2023

AbstractThe mixing of [V10O28]6− decavanadate anions with a dicationic gemini surfactant (gem) leads to the spontaneous self‐assembly of surfactant‐templated nanostructured arrays of decavanadate clusters. Calcination of the material under air yields highly crystalline, sponge‐like V2O5 (gem‐V2O5). In contrast, calcination of the amorphous tetrabutylammonium decavanadate allows isolation of a more agglomerated V2O5 consisting of very small crystallites (TBA‐V2O5). Electrochemical analysis of the materials’ performance as lithium‐ion intercalation electrodes highlights the role of morphology in cathode performance. The large crystallites and long‐range microstructure of the gem‐V2O5 cathode deliver higher initial capacity and superior capacity retention than TBA‐V2O5. The smaller crystallite size and higher surface area of TBA‐V2O5 allow faster lithium insertion and superior rate performance to gem‐V2O5.
Spectroscopic Identification of Diphosphene HPPH and Isomeric Diphosphinyldene PPH2
Authors: Lu Bo , Wang Lina , Jiang Xin , Rauhut Guntram , Zeng Xiaoqing 
Published: January 2023

AbstractThe simplest diphosphene HPPH and isomeric diphosphinyldene PPH2 features prototype phosphorus‐phosphorus multiple bonding properties that have been of long‐standing interest in main‐group chemistry. Herein, we report the observation of cis‐HPPH, trans‐HPPH, and PPH2 among the respective laser photolysis products of phosphine (PH3) and diphosphine (P2H4) in solid N2‐ and Ar‐matrices at 10 K. The identification of these P2H2 isomers with matrix‐isolation IR and UV/Vis spectroscopy is supported by D‐isotope labeling and the quantum chemical calculations at the CCSD(T)‐F12a/cc‐pVTZ‐F12 level using configuration‐selective vibrational configuration interaction theory (VCI). Bonding analyses suggest that the two conformers of HPPH contain standard PP double bonds, whereas, PPH2 resembles P2 in having partial PP triple bond due to the H2P←P π bonding interaction.
Triggered Functional Dynamics of AsLOV2 by Time‐Resolved Electron Paramagnetic Resonance at High Magnetic Fields
Authors: Maity Shiny , Price Brad D. , Wilson C. Blake , Mukherjee Arnab , Starck Matthieu , Parker David , Wilson Maxwell Z. , Lovett Janet E. , Han Songi , Sherwin Mark S. 
Published: January 2023

AbstractWe present time‐resolved Gd−Gd electron paramagnetic resonance (TiGGER) at 240 GHz for tracking inter‐residue distances during a protein's mechanical cycle in the solution state. TiGGER makes use of Gd‐sTPATCN spin labels, whose favorable qualities include a spin‐7/2 EPR‐active center, short linker, narrow intrinsic linewidth, and virtually no anisotropy at high fields (8.6 T) when compared to nitroxide spin labels. Using TiGGER, we determined that upon light activation, the C‐terminus and N‐terminus of AsLOV2 separate in less than 1 s and relax back to equilibrium with a time constant of approximately 60 s. TiGGER revealed that the light‐activated long‐range mechanical motion is slowed in the Q513A variant of AsLOV2 and is correlated to the similarly slowed relaxation of the optically excited chromophore as described in recent literature. TiGGER has the potential to valuably complement existing methods for the study of triggered functional dynamics in proteins.
Generation of Allylmagnesium Reagents by Hydromagnesiation of 2‐Aryl‐1,3‐dienes
Authors: Li Yihang , Chen Jiahua , Ng Jaslyn Jing Wen , Chiba Shunsuke 
Published: January 2023

AbstractA protocol for the generation of allylmagnesium reagents from 2‐aryl‐1,3‐dienes was developed using magnesium hydride (MgH2) that is generated in situ by solvothermal treatment of sodium hydride (NaH) and magnesium iodide (MgI2) in tetrahydrofuran (THF). Downstream functionalization of the resulting allylmagnesium reagents with carbonyl compounds or alkyl (pseudo)halides delivers branched products having an allylic quaternary carbon center, whereas that with chlorosilanes resulted in formation of linear allylsilanes in regio and stereoselective manners. Further derivatizations of the homoallylic alcohols and allylsilanes were also demonstrated.
Highly Reactive Hydrocarbon Soluble Alkylsodium Reagents for Benzylic Aroylation of Toluenes using Weinreb Amides
Authors: Anderson David E. , Tortajada Andreu , Hevia Eva 
Published: January 2023

AbstractDeaggregating the alkyl sodium NaCH2SiMe3 with polydentate nitrogen ligands enables the preparation and characterisation of new, hydrocarbon soluble chelated alkylsodium reagents. Equipped with significantly enhanced metalating power over their organolithium counterparts, these systems can promote controlled sodiation of weakly acidic benzylic C−H bonds from a series of toluene derivatives under mild stoichiometric conditions. This has been demonstrated through the benzylic aroylation of toluenes with Weinreb amides, that delivers a wide range of 2‐arylacetophenones in good to excellent yields. Success in isolating and determining the structures of key organometallic intermediates has provided useful mechanistic insight into these new sodium‐mediated transformations.
Anticancer agents incorporating the N‐acylhydrazone scaffold: Progress from 2017 to present
Authors: Kassab Asmaa E. 
Published: January 2023

AbstractThe N‐acylhydrazone motif has been shown to be particularly adaptable and promising in the area of medicinal chemistry and drug development, due to its significant biological and pharmacological characteristics. Moreover, N‐acylhydrazones are appealing synthetic and biological tools because of their simple and straightforward synthesis. This scaffold has emerged as a fundamental building block for the synthesis of bioactive compounds. Particularly, the N‐acylhydrazone scaffold served as a base for the synthesis of a number of potent anticancer agents acting via different mechanisms. An updated summary of the anticancer activity of N‐acylhydrazone derivatives described in the literature (from 2017 to 2022) is provided in the current review. It discusses the structure–activity relationship (SAR) of N‐acylhydrazone derivatives exhibiting anticancer potential, which could be helpful in designing and developing new derivatives as effective antiproliferative candidates in the future.
Magnetic‐responsive Covalent Adaptable Networks
Authors: Liang Huan , Wei Yen , Ji Yan 
Published: January 2023

AbstractCovalent adaptable networks (CANs) are reprocessable polymers whose structural arrangement is based on the recombination of dynamic covalent bonds. Composite materials prepared by incorporating magnetic particles into CANs attract much attention due to their remote and precise control, fast response speed, high biological safety and strong penetration of magnetic stimuli. These properties often involve magnetothermal effect and direct magnetic‐field guidance. Besides, some of them can also respond to light, electricity or pH values. Thus, they are favorable for soft actuators since various functions are achieved such as magnetic‐assisted self‐healing (heating or at ambient temperature), welding (on land or under water), shape‐morphing, and so on. Although magnetic CANs just start to be studied in recent two years, their advances are promised to expand the practical applications in both cutting‐edge academic and engineering fields. This review aims to summarize recent progress in magnetic‐responsive CANs, including their design, synthesis and application.
Materialeffiziente Tübbings mit Hybridbewehrung – Entwurf, Herstellung und Bauteilexperimente
Authors: Petraroia Diego Nicolás , Ahrens Mark Alexander , Mark Peter 
Published: January 2023

AbstractLasteinleitungsstellen von Tunneln aus Tübbings sind lokal hoch beansprucht. Insbesondere betrifft dies die Ansatzpunkte der Vorschubpressen und die Längsfugen als Kontaktstellen zwischen den einzelnen Segmenten in Ringrichtung. Gewöhnlich dominiert die Teilflächenpressung der Längsfuge die Dimensionierung des ganzen Tübbings; abseits davon wird er jedoch nicht voll ausgenutzt. Im Beitrag werden zwei Lösungskonzepte vorgestellt. Eines verstärkt die Tragfähigkeit der Längsfugen im Bereich der Lasteinleitung durch hochfesten Beton und hybride Bewehrung aus Stabstahl und Stahlfasern. Übrige Tübbingteile werden weiterhin in Normalbeton ausgeführt. Darauf abgestimmt erfolgt die Betonage; stehend und hybrid. Alternativ werden Tübbings aus durchgehend hochfestem Beton mit Aussparungen entwickelt. Entsprechende Entwürfe werden im Großmaßstab im Labor umgesetzt und hinsichtlich ihrer Tragfähigkeit geprüft. Sie liegt bei beiden mit ca. 75 % bzw. 86 % deutlich über derjenigen eines herkömmlichen Referenztübbings. Auch hinsichtlich der CO2‐Äquivalente zeigen sich Einsparpotenziale von ca. 35 %. Zudem verringert die geringere notwendige Tübbingdicke den Ausbruchquerschnitt, was Kostenvorteile bringt.
Cannabinoids in neuroinflammatory disorders: Focusing on multiple sclerosis, Parkinsons, and Alzheimers diseases
Authors: Abd‐Nikfarjam Bahareh , Dolati‐Somarin Amirhossein , Baradaran Rahimi Vafa , Askari Vahid Reza 
Published: January 2023

AbstractThe medicinal properties of cannabis and cannabinoid‐derivative are entirely investigated and known. In addition, the identification of psychotropic plant cannabinoids has led to more studies regarding the cannabinoid system and its therapeutic features in the treatment and management of clinical symptoms of neuroinflammatory disorders, such as multiple sclerosis (MS), Parkinsons disease (PD), and Alzheimers disease (AD). In fact, cannabinoid agonists are able to control and regulate inflammatory responses. In contrast to the cannabinoid receptor type 1 (CB1) and its unwanted adverse effects, the cannabinoid receptor type 2 (CB2) and its ligands hold promise for new and effective therapeutic approaches. So far, some successes have been achieved in this field. This review will discuss an outline of the endocannabinoid system's involvement in neuroinflammatory disorders. Moreover, the pharmacological efficacy of different natural and synthetic preparations of phytocannabinoids acting on cannabinoid receptors, particularly in MS, PD, and AD, will be updated. Also, the reasons for targeting CB2 for neurodegeneration will be explained.
Improvement of Metabolic and Histological Changes of Adiposity in Rats by Synthetic Oleoyl Chalcones
Authors: AlKhathami Azza A. M. , Saad Hosam A. , Fareed Fareed A. , El‐Shafey Eman S. , Elsherbiny Eslam S. , El Nahas Mamdouh R. , Aly Mohamed R. E. 
Published: January 2023

AbstractWe previously reported that synthetic oleoyl chalcones had a favorable effect to alleviate metabolic consequences of obesity in male SD rats. In this work, we prepared and characterized by spectroscopic tools, a set of six oleoyl chalcones (5a–c, 10 and 11a,b). The comparative effects of the previously prepared oleoyl chalcones and their new synthetic analogs on metabolic and histological changes in obese male SD rats were studied. It was found that the oleoyl chalcones IIIa and IV were the best in improving many metabolic parameters, e. g., FBG, FI, ISI, TG, and total cholesterol. They cured systemic inflammation, through inhibition of the TNF‐α and induction of adiponectin production. Moreover, chalcones IIIa and IV alleviated the oxidative stress accompanying obesity through the induction of the antioxidant enzymes GPX, SOD and CAT besides, GSH. Interestingly, chalcones IIIa and IV exerted hepatoprotective potency and ameliorated the manifestations of NAFLD via inhibition of apoptosis and induction of autophagy of hepatic cells. In conclusion, the oleoyl chalcones IIIa and IV were the most effective candidates among the series of synthetic chalcones in correcting body weight and the consequent metabolic and histological changes in adiposity.
DMAPO/Boc2O‐Mediated One‐Pot Direct N‐Acylation of Less Nucleophilic N‐Heterocycles with Carboxylic Acids
Authors: Umehara Atsushi , Shimizu Soma , Sasaki Makoto 
Published: January 2023

AbstractIn contrast to the considerable progress in the development of methodologies for amide bond formation in amines, the development of direct N‐acylation of less nucleophilic N‐heterocycles and amides with carboxylic acids is still challenging. In this report, we describe the direct N‐acylation of less nucleophilic heterocycles and amides with carboxylic acids promoted by the 4‐(N,N‐dimethylamino)pyridine N‐oxide (DMAPO)/di‐tert‐butyl dicarbonate (Boc2O) system. The new one‐pot method, which does not involve pre‐activation of substrates, enables the direct N‐acylation of a wide variety of nitrogen nucleophiles such as indole, carbazole, pyrrole, pyrazole, lactam, oxazolidinone, and anilide with carboxylic acids in high yield. The new method also exhibits excellent functional group tolerance and broad substrate scope. As the present method is practical, operationally simple, and scalable, it should find wide applications in both academic and industrial laboratories.
The relationships among the big 5 personality factors and negative career thoughts
Authors: Coleman Christine E. , Lenz Janet G. , Osborn Debra S. 
Published: January 2023

AbstractCollege students may present with career concerns that are interrelated with personality and psychological factors. Various authors have highlighted the need for career practitioners to take a holistic approach with clients seeking assistance. This research examined the intersection of personal and career characteristics, specifically personality and negative career thoughts. A total of 128 undergraduate students in five career course sections completed the NEO‐Five Factor Inventory and the Career Thoughts Inventory. A hierarchical multiple regression showed that 27.1% of the variability in negative career thoughts was explained by the combined effect of Neuroticism, Extraversion, Openness, Agreeableness, and Conscientiousness. Personality factors had significant moderate correlations with specific aspects of negative thinking, including Decision‐Making Confusion (DMC) and Neuroticism and Conscientiousness. Commitment Anxiety (CA) was significantly correlated with Neuroticism and Conscientiousness. We discuss how the findings highlight the intersection of career and personality factors, and the implications for theory, practice, and future research
Manipulation of Organic Afterglow in Fluoranthene‐Containing Dopant‐Matrix Systems: From Conventional Room‐Temperature Phosphorescence to Efficient Red TADF‐Type Organic Afterglow
Authors: Xu Yaxian , Yuan Shou , Wang Guangming , Li Jiuyang , Wang Xuepu , Li Xun , Ding Shuhui , Chen Xuefeng , Zhang Kaka 
Published: January 2023

AbstractIt remains challenging to fabricate highly‐efficient and long‐lived organic afterglow materials, especially in the case of red afterglow systems. Here we develop advanced charge transfer (CT) technology to boost afterglow efficiency and lifetimes in fluoranthene‐containing dopant‐matrix systems. First, organic CT molecules possess singlet‐triplet splitting energy (ΔEST) of around 0.5 eV, much smaller than localized excitation systems. Second, upon doping into suitable organic matrices, dipole‐dipole interactions between 1CT states and organic matrices reduce 1CT levels with less effect on 3CT levels, and thus further narrow ΔEST and enhance intersystem crossing. Third, the rigid planar structure of fluoranthene groups and the rigid microenvironment provided by organic matrices can suppress phosphorescence quenching. Forth, the multiple donor design enables spectral red‐shifts to red region and switches on TADF mechanism to improve afterglow efficiency to 13.1 % and maintain afterglow lifetime of 0.1 s. Such high‐performance afterglow materials have been rarely explored in reported studies.
Access to Amide‐Linked Organic Cages by in situ Trapping of Metastable Imine Assemblies: Solution Phase Bisamine Recognition
Authors: Andrews Keith G. , Christensen Kirsten E. 
Published: January 2023

AbstractMolecular cages are sought after as receptors and catalysts. However, typical dynamic covalent chemistry approaches restrict the shape‐persistence, solubility and stability of self‐assembled organic cages. As a result, organic cages occupy a narrow chemical and functional space, and solution‐phase applications and studies remain rare. We report an in situ trapping protocol, using Pinnick oxidation conditions, to convertsolublemetastable imine assemblies to robust amide cages, and exemplify the method to access previously inaccessible organic cages. The new cages are internally functionalised with two constrained and diametrically opposed carboxylic acid groups that can distinguish between functionalised piperazines in THF. We anticipate our approach will broaden access to robust, soluble, self‐assembled organic cages of an unsymmetrical or semi‐flexible nature, which in turn will drive advances in solution‐phase applications of molecular cages.
Patient‐specific finite element simulation of peripheral artery percutaneous transluminal angioplasty to evaluate the procedure outcome without stent implantation
Authors: Helou Bernard , Bel‐Brunon Aline , Dupont Claire , Ye Wenfeng , Silvestro Claudio , Rochette Michel , Lucas Antoine , Kaladji Adrien , Haigron Pascal 
Published: January 2023

AbstractThe purpose of this work is to present a patient‐specific (PS) modeling approach for simulating percutaneous transluminal angioplasty (PTA) endovascular treatment and assessing the balloon sizing influence on short‐term outcomes in peripheral arteries, i.e. without stent implantation. Two 3D PS stenosed femoral artery models, one with a dominant calcified atherosclerosis while the other with a lipidic plaque, were generated from pre‐operative computed tomography angiography images. Elastoplastic constitutive laws were implemented within the plaque and artery models. Implicit finite element method (FEM) was used to simulate the balloon inflation and deflation for different sizings. Besides vessel strains, results were mainly evaluated in terms of the elastic recoil ratio (ERR) and lumen gain ratio (LGR) attained immediately after PTA. Higher LGR values were shown within the stenosed region of the lipidic patient. Simulated results also showed a direct and quantified correlation between balloon sizing and LGR and ERR for both patients after PTA, with a more significant influence on the lumen gain. The max principal strain values in the outer arterial wall increased at higher balloon sizes during inflation as well, with higher rates of increase when the plaque was calcified. Results show that our model could serve in finding a compromise for each stenosis type: maximizing the achieved lumen gain after PTA, but at the same time without damaging the arterial tissue. The proposed methodology can serve as a step toward a clinical decision support system to improve angioplasty balloon sizing selection prior to the surgery.
Hydrodynamics and habitat interact to structure fish communities within terminal channels of a tidal freshwater delta
Authors: Huntsman Brock M. , Young Matthew J. , Feyrer Frederick V. , Stumpner Paul R. , Brown Larry R. , Burau Jon R. 
Published: January 2023

AbstractTerminal channels were historically a common feature of tidal delta ecosystems but have become increasingly rare as landscapes have been modified. Tidal hydrodynamics are a defining feature in tidal terminal channel ecosystems from which native aquatic communities have evolved. However, few studies have explored the relationship between fish community structure and hydrodynamics in these tidal terminal channel ecosystems. We sampled fish communities throughout a network of terminal channels within the northeasternmost region of the San Francisco Estuary to determine the relationship between fish community structure and hydrodynamics within these environments. We collected two years (2017 and 2018) of fish community samples using gill nets and analyzed data using multivariate community analyses and count models. We found metrics of fish diversity and counts of native fishes to be greatest upstream (farthest from tidal influence) of the tidal excursion within terminal channels. Counts of non‐native fishes were less affected by this hydrodynamic feature of terminal channels and more tightly correlated to local habitat conditions (e.g., water temperature, depth). Our results suggest that channel hydrodynamics plays a role in structuring fish communities within terminal channels, particularly native fishes. These results indicate that hydrodynamics in tidal delta ecosystems may be able to be altered in ways that benefit native fishes without the cost of water pumping.