bluuebunny/crossref_metadata_2025_split huggingface dataset:
Becoming Reflective Practitioners: Gender GAP Analysis of Mathematics Student Teachers’ Reflective Practices
Authors: Olawale Babawande Emmanuel , Hendricks Winston 
Published: May 2023

While reflective thinking practices are thought to be a factor in building bridges between a course of study and personal experience resulting in engaging and personalized learning activities, the present study examined the potential disparities in reflective thinking practices and how they influence preservice mathematics teachers' behavior. Underpinned by a positivist paradigm, the present study employed a quantitative research approach and a survey design. Data was collected from three hundred and fifty-nine mathematics student teachers who were preparing to become mathematics teachers once they had obtained a Bachelor of Education (B.Ed.) degree. Data collected was therefore analyzed through the use of descriptive statistics. Lifelong learning skills, self-assessment, self-belief, teaching awareness, and reflective thinking were all examined using a framework based on five components. Research findings revealed that while reflective thinking practices are often emphasized in teacher education programs, results clearly show that the process of reflective practices is conceptualized differently by female and male participants. Research findings also revealed that constructs such as lifelong learning skills, self-assessment ability, and teaching awareness have a more decisive influence on male participants than their female counterparts. This resulted in male participants having less perception of the usefulness of reflective thinking practices. Based on the findings, it was suggested that various support systems should be developed in mathematics teacher education programs to facilitate more independent and self-directed reflective thinking practices among both female and male mathematics students teachers.
Keywords: Classroom Practices, Gender GAP, Reflective Thinking, Self-Belief, Teacher Education.
GAMBARAN FAKTOR PENGETAHUAN PASIEN DALAM PELAYANAN BPJS
Authors: Tullah Adilla , Anggraini Yuliza , Wibowo Hendry 
Published: May 2023

Latar Belakang: Pengetahuan merupakan sebuah hasil tahu yang diperoleh setelah melakukan interaksi terhadap suatu objek. Faktor yang berkaitan dengan pengetahuan yaitu umur, tingkat pendidikan, pekerjaan dan sumber informasi. Adanya pasien yang belum memahami bagaimana prosedur dalam pelayanan BPJS. Tujuan: untuk mengetahui bagaimana distribusi frekuensi faktor yang berkaitan dengan pengetahuan pasien dalam pelayanan BPJS. Metodologi: Penelitian ini dilakukan di Rumah Sakit Madina Bukittinggi dengan menggunakan metode Penelitian deskriptif pendekatan kuantitatif, dengan jumlah sampel sebanyak 76 orang dengan menggunakan teknik accidental sampling. Hasil: penelitian menunjukan bahwa lebih dari sebahagian responden dengan pengetahuan rendah yaitu sebesar (51,3%) dengan umur 21-30 dan 41-50 tahun (25%) dengan tingkat pendidikan tinggi (55,3%) serta responden dengan kategori tidak bekerja (36,8%) dan media cetak merupakan kategori sumber informasi yang paling banyak diperoleh oleh responden sebesar (46,1%). Diskusi: Dari penelitian ini adalah masih rendahnya pengetahuan pasien dalam pelayanan BPJS, saran diharapkan kepada pihak rumah sakit untuk memberikan informasi kepada anggota BPJS dengan lebih maksimal, baik secara langsung, media cetak maupun media elektronik.
GAMBARAN FUNGSI MANAJEMEN KEPALA RUANGAN DI RUANG RAWAT INAP
Authors: Suci Vauzyatari Tilawa , Susanti Elsi , Azwita Sylvi Nezi 
Published: May 2023

Belakang: Manajemen berfungsi untuk memberikan arahan, koordinasi, dan pengendalian yang baik berdasarkan rencana yang sebelumnya telah ditetapkan, fungsi manajemen secara umum ada empat yaitu fungsi perencanaan, fungsi pengorganisasian, fungsi pengawasan, dan fungsi pengarahan. Empat fungsiini sangat dibutuhkan untuk menetukan apakah fungsi manajemen kepala ruangan terlaksakan atau belum. Tujuan: Untuk mengetahui gambaran fungsi manajemen kepala ruang di ruang awat inap RSUD Prof. Dr. MA. Hanfiah SM Batusangkar. Metodologi: Jenis penelitian ini merupakan penelitian kuantitatif dengan teknik pengambilan sampel random sempling.Populasi dalam penelitian ini 147 perawat rawat inap dan sampel 45 responden. Hasil: fungsi manajemen kepala ruangan, fungsi perencanaan diperoleh gambaran bahwa dari 45 responden 24 orang (53,3%) menyatakan kurang baik dan 21 orang (46,7%) menyatakan baik, fungsi pengorganisasian kepala ruang diperoleh gambaran bahwa 13 orang (28,9%) menyatakan kurang baik dan 32 orang (71,1%) menyatakan baik, fungsi pengarahan kepala ruangan diperoleh gambaran bahwa 21 orang (46,7%) menyatakan kurang baik dan 24 orang (53,3%) menyatakan baik, fungsi pengawasan kepala ruangan diperoleh gambaran bahwa 32 orang (71,1%) menyatakan kurang baik dan 13 orang (28,9%) menyatakan baik. Diskusi: bahwa fungsi manajemen kepala ruangan di ruang rawat inap masih belum berjalan dengan baik seperti fungsi perencanaan dan pengawasan, untuk fungsi pengorganisasian dan fungsi pengarahan sudah berjalan dengan baik.Saran untuk kepala ruangan agar meningkatkan fungsi manajemen perencanaan dan pengawasan serta mempertahankan fungsi pengorganisasian dan fungsi pengarahan supaya tujuan organisasai nya dapat tercapai.
Sporadic Use of Antibiotics in Older Adults and the Risk of Dementia: A Nested Case–Control Study Based on German Health Claims Data
Authors: Rakuša Elena , Fink Anne , Tamgüney Gültekin , Heneka Michael T. , Doblhammer Gabriele 
Published: May 2023

Background: Antibiotics for systemic use may increase the risk of neurodegeneration, yet antibiotic therapy may be able to halt or mitigate an episode of neurodegenerative decline. Objective: To investigate the association of sporadic use of antibiotics and subsequent dementia risk (including Alzheimer’s disease). Methods: We used data from the largest public health insurance fund in Germany, the Allgemeine Ortskrankenkasse (AOK). Each of the 35,072 dementia cases aged 60 years and older with a new dementia diagnosis during the observation period from 2006 to 2018 was matched with two control-patients by age, sex, and time since 2006. We ran conditional logistic regression models for dementia risk in terms of odds ratios (OR) as a function of antibiotic use for the entire antibiotic group and for each antibiotic subgroup. We controlled for comorbidities, need for long-term care, hospitalizations, and nursing home placement. Results: Antibiotic use was positively associated with dementia (OR = 1.18, 95% confidence interval (95% CI):1.14–1.22), which became negative after adjustment for comorbidities, at least one diagnosis of bacterial infection or disease, and covariates (OR = 0.93, 95% CI:0.90–0.96). Subgroups of antibiotics were also negatively associated with dementia after controlling for covariates: tetracyclines (OR = 0.94, 95% CI:0.90–0.98), beta-lactam antibacterials, penicillins (OR = 0.93, 95% CI:0.90–0.97), other beta-lactam antibacterials (OR = 0.92, 95% CI:0.88–0.95), macrolides, lincosamides, and streptogramins (OR = 0.88, 95% CI:0.85–0.92), and quinolone antibacterials (OR = 0.96, 95% CI:0.92–0.99). Conclusion: Our results suggest that there was a decreased likelihood of dementia for preceding antibiotic use. The benefits of antibiotics in reducing inflammation and thus the risk of dementia need to be carefully weighed against the increase in antibiotic resistance.
Extracellular Tau Oligomers Damage the Axon Initial Segment
Authors: Best Merci N. , Lim Yunu , Ferenc Nina N. , Kim Nayoung , Min Lia , Wang Dora Bigler , Sharifi Kamyar , Wasserman Anna E. , McTavish Sloane A. , Siller Karsten H. , Jones Marieke K. , Jenkins Paul M. , Mandell James W. , Bloom George S. 
Published: May 2023

Background: In Alzheimer’s disease (AD) brain, neuronal polarity and synaptic connectivity are compromised. A key structure for regulating polarity and functions of neurons is the axon initial segment (AIS), which segregates somatodendritic from axonal proteins and initiates action potentials. Toxic tau species, including extracellular oligomers (xcTauOs), spread tau pathology from neuron to neuron by a prion-like process, but few other cell biological effects of xcTauOs have been described. Objective: Test the hypothesis that AIS structure is sensitive to xcTauOs. Methods: Cultured wild type (WT) and tau knockout (KO) mouse cortical neurons were exposed to xcTauOs, and quantitative western blotting and immunofluorescence microscopy with anti-TRIM46 monitored effects on the AIS. The same methods were used to compare TRIM46 and two other resident AIS proteins in human hippocampal tissue obtained from AD and age-matched non-AD donors. Results: Without affecting total TRIM46 levels, xcTauOs reduce the concentration of TRIM46 within the AIS and cause AIS shortening in cultured WT, but not TKO neurons. Lentiviral-driven tau expression in tau KO neurons rescues AIS length sensitivity to xcTauOs. In human AD hippocampus, the overall protein levels of multiple resident AIS proteins are unchanged compared to non-AD brain, but TRIM46 concentration within the AIS and AIS length are reduced in neurons containing neurofibrillary tangles. Conclusion: xcTauOs cause partial AIS damage in cultured neurons by a mechanism dependent on intracellular tau, thereby raising the possibility that the observed AIS reduction in AD neurons in vivo is caused by xcTauOs working in concert with endogenous neuronal tau.
A Mixed-Method Study Exploring Patient-Experienced and Caregiver-Reported Benefits and Side Effects of Corticosteroid Use in Duchenne Muscular Dystrophy
Authors: Fischer Ryan , Porter Katherine , Donovan Joanne M. , Scavina Mena T. , Armstrong Niki , Denger Brian , Hasham Shabir , Peay Holly 
Published: May 2023

Background: Corticosteroids are recommended to all people with Duchenne as standard of care; patient experience data is important to guide corticosteroid decision making and as a comparator for new treatment options. Objective: This study assesses patient and caregiver-reported benefits and side effects from corticosteroids to treat Duchenne muscular dystrophy, their importance, and satisfaction. Methods: Using one-on-one interviews ( n = 28) and an online survey ( n = 236), parents and adults with Duchenne reported corticosteroid benefits and side effects rated as both experienced and important. Results: Benefits to breathing, heart function, arm strength, slowing progression of weakness, and getting around were rated as particularly important, regardless of ambulatory status. Important side effects included increased fracture risk, unwanted weight gain, and diabetes/prediabetes. Parents rated behavior issues and adults rated delayed puberty as having high importance. Being ambulatory was independently associated with reporting more net benefit ( p = 0.02). For side effects, parent scores were significantly higher than adult score ( p = 0.02). Corticosteroid type was not significant. Participants were, overall, satisfied with corticosteroids (means ranging from 6.2 to 7.7 on a scale of 0–10), with no significant differences based on corticosteroid type. Conclusions: Overall, most participants were satisfied with the use of corticosteroids. While a range of side effects were rated as important and relatively common, individuals using corticosteroids and their caregivers indicate that benefits outweigh the side effects. Qualitative data indicate that high acceptability is influenced by lack of treatment alternatives. Patient experience data on use of corticosteroids in Duchenne may be relevant to drug development, regulatory assessment of new treatments, and to families making decisions about corticosteroid use.
Brain MRI Abnormalities, Epilepsy and Intellectual Disability in LAMA2 Related Dystrophy – a Genotype/Phenotype Correlation
Authors: Camelo Clara Gontijo , Artilheiro Mariana Cunha , Martins Moreno Cristiane Araújo , Ferraciolli Suely Fazio , Serafim Silva André Macedo , Fernandes Tatiana Ribeiro , Lucato Leandro Tavares , Rocha Antônio José , Reed Umbertina Conti , Zanoteli Edmar 
Published: May 2023

Background: LAMA2-related muscular dystrophy is a disorder that causes muscle weakness and varies in severity, from a severe, congenital type to a milder, late-onset form. However, the disease does not only affect the muscles, but has systemic involvement and can lead to alterations such as brain malformation, epilepsy and intellectual disability. Objective: Describe the frequency of cortical malformations, epilepsy and intellectual disability in LAMA2-RD in a Brazilian cohort and correlate the neurological findings to genetic and motor function. Methods: This is an observational study of 52 LAMA2-RD patients, who were divided into motor function subgroups and compared based on brain MRI findings, epilepsy, intellectual disability, and type of variants and variant domains. Results: 44 patients (84.6%) were only able to sit, and 8 patients (15.4%) were able to walk. 10 patients (19.2%) presented with cortical malformations (polymicrogyria, lissencephaly-pachygyria, and cobblestone),10 patients (19.2%) presented with epilepsy, and 8 (15.4%) had intellectual disability. CNS manifestations correlated with a more severe motor phenotype and none of the patients able to walk presented with cortical malformation or epilepsy. There was a relation between gene variants affecting the laminin- α2 LG-domain and the presence of brain malformation ( P = 0.016). There was also a relation between the presence of null variants and central nervous system involvement. A new brazilian possible founder variant was found in 11 patients (21,15%) (c.1255del; p. Ile419Leufs*4). Conclusion: Cortical malformations, epilepsy and intellectual disability are more frequent among LAMA2-RD patients than previously reported and correlate with motor function severity and the presence of variants affecting the laminin- α2 LG domain. This brings more insight fore phenotype-genotype correlations, shows the importance of reviewing the brain MRI of patients with LAMA2-RD and allows greater attention to the risk of brain malformation, epilepsy, and intellectual disability in those patients with variants that affect the LG domain.
The Traditional Karonese Oil as Ancestral Heritage
Authors: Sari Ellieka , Sitepu Runtung , Saidin  , Maria  
Published: May 2023

Every indigenous people are familiar with traditional medicine and medical techniques in order to maintain life in an atmosphere of support for community medicine and medical techniques. Traditional knowledge, especially traditional medicine, is Karonese Oil which has important benefit. This study examines the openness of the ancestral heritage of traditional knowledge of Karonese Oil. In this study, it is hoped that a renewal of regulations on traditional knowledge is closely related to regulations on the protection of traditional medicine because of medicine and techniques that have not received adequate legal protection. Data collection is carried out descriptive qualitative research, descriptive is a problem formulation that guides research to explore or portray the social situation to be studied thoroughly, broadly and in depth to craftsmen or traditional Karo oil activists. The data were analyzed qualitatively by using a legal theory approach as a rationale. Indigenous peoples rule on the protection of traditional knowledge of ancestral heritage of traditional Karo tribe oil. The Karonese tribe has various kinds of knowledge of medicine and traditional medicine techniques, especially Karonese oil. Updating on traditional knowledge that are closely related to regulations on the protection of traditional medicine due to inadequate medicines and techniques. This is in the form of regulations concerning the draft law on the protection and use of intellectual property, traditional knowledge and traditional cultural expressions, which until now have not been ratified by the Government.
Comparison of clinical outcomes between active and permissive blood pressure management in extremely preterm infants
Authors: Aladangady Narendra , Sinha Ajay , Banerjee Jayanta , Asamoah Felix , Mathew Asha , Chisholm Phillippa , Kempley Steven , Morris Joan 
Published: May 2023

Background: There remains uncertainty about the definition of normal blood pressure (BP), and when to initiate treatment for hypotension for extremely preterm infants. To determine the short-term outcomes of extremely preterm infants managed by active compared with permissive BP support regimens during the first 72 hours of life. Method: This is a retrospective medical records review of 23+0–28+6 weeks’ gestational age (GA) infants admitted to neonatal units (NNU) with active BP support (aimed to maintain mean arterial BP (MABP) >30 mmHg irrespective of the GA) and permissive BP support (used medication only when babies developed signs of hypotension) regimens. Babies admitted after 12 hours of age, or whose BP data were not available were excluded. Results: There were 764 infants admitted to the participating hospitals; 671 (88%) were included in the analysis (263 active BP support and 408 permissive BP support). The mean gestational age, birth weight, admission temperature, clinical risk index for babies (CRIB) score and first haemoglobin of infants were comparable between the groups. Active BP support group infants had consistently higher MABP and systolic BP throughout the first 72 hours of life (p<0.01). In the active group compared to the permissive group 56 (21.3%) vs 104 (25.5%) babies died, and 21 (8%) vs 51 (12.5%) developed >grade 2 intra ventricular haemorrhage (IVH). Death before discharge (adjusted OR 1.38 (0.88 – 2.16)) or IVH (1.38 (0.96 – 1.98)) was similar between the two groups. Necrotising enterocolitis (NEC) ≥stage 2 was significantly higher in permissive BP support group infants (1.65 (1.07 – 2.50)). Conclusions: There was no difference in mortality or IVH between the two BP management approaches. Active BP support may reduce NEC. This should be investigated prospectively in large multicentre randomised studies.
RANCANG BANGUN CRM BERBASIS WEB PADA UD. TIMBUL REZEKI
Authors: Khoirani Fahriza , Efendi Bachtiar , Sembiring Muhammad Ardiansyah 
Published: May 2023

Abstrack: UD. Timbul Rezeki, located on Jalan Sei Alim Hasak, Sei Dadap District, Asahan Regency, North Sumatra Province is one of the businesses engaged in the business of selling building materials such as cement, paint, nails, wood and other building materials. In carrying out selling and ordering activities, the goods are still done manually and also not computerized, such as customers buying building materials by coming directly to UD. Rezeki arises or by calling the telephone number of UD. Sustenance arises to place an order for building materials. This makes it difficult for customers to know the quality of the building materials available at UD. Sustenance arises. The purpose of this study is to improve customer service at UD. Sustenance arises by implementing Customer Relationship Management. The method used in this research is to apply the method of Customer Relationship Management (CRM). The results of implementing Customer Relationship Management can improve service to customers at UD. Sustenance arises by providing information about products, account registration, product orders, media comments and product ratings, chats, coupon vouchers, discounts, and product catalogs as product promotion media. Keywords: CRM; Sales; Building Materials; Web. Abstrak: UD. Timbul Rezeki berlokasi Jalan Sei Alim Hasak Kecamatan Sei Dadap, Kabupaten Asahan, Provinsi Sumatera Utara merupakan salah satu usaha bisnis yang bergerak di bidang usaha penjualan material bahan bagunan seperti semen, cat, paku, kayu dan bahan-bahan bangunan lainnya. Dalam melakukan aktivitas menjual dan pemesanan barangnya masih dilakukan secara manual dan juga belum terkomputerisasi seperti pelanggan melakukan pembelian bahan-bahan bangunan dengan datang langsung ke UD. Timbul Rezeki atau dengan menghubungi nomor telepon pihak UD. Timbul Rezeki untuk melakukan pemesanan bahan bagunan. Hal ini yang membuat pelanggan sulit mengetahui kualitas bahan-bahan bangunan yang ada di UD. Timbul Rezeki. Tujuan penelitian ini adalah Untuk meningkatkan pelayanan pelanggan pada UD. Timbul Rezeki dengan menerapkan Customer Relationship Management. Adapun metode yang digunakan dalam penelitian ini adalah dengan menerapkan metode Customer Relationship Management (CRM). Hasil menerapkan menerapkan Customer Relationship Management dapat meningkatkan pelayanan terhadap pelangg:an di UD. Timbul Rezeki dengan memberikan informasi tentang produk, pendaftaran akun, pemesanan produk, media komentar dan rating produk, chatting, voucher kupon, diskon, serta catalog produk sebagai media promosi produk. Kata Kunci : CRM; Penjualan; Material Bahan Bangunan; Web.
PENERAPAN METODE AHP PENENTUAN PENERIMA BANTUAN INDONESIA PINTAR PADA SDN 010069 PUNGGULAN
Authors: Wita Dwi Agus , Siagian Yessica , Rohminatin Rohminatin 
Published: May 2023

Abstract: In 2014 the government created the Smart Indonesia Program (PIP) which became part of the improvement of Assistance for Poor Students. PIP is assistance from the government for the poor in terms of education provided to families with school-age children (6-21 years) coming from poor families. Public Elementary School 010069 Punggulan Village is obliged to register students who have KIP with Dapodik so that they can immediately receive PIP benefits. The obstacle faced by SDN 010069 Punggulan Village is that there are many criteria that must be taken into account so that it is difficult to determine the priority of potential PIP recipients. To overcome this problem, it is necessary to have a system to determine the priority of potential PIP recipients by adding some more basic criteria. In this study a decision support system was designed using the AHP (Analitycal Hierarchy Process) method with several criteria, namely Student Active Status, Poor Certificate, Orphan Condition, Parents' Salary, Attendance Presentation. In this application, the final result is the priority ranking of students who will receive PIP assistance. Based on these problems, it can be concluded that there are many criteria for poor students who do not have KIP, making it difficult for SDN 010069 Punggulan Village to determine the priorities of poor students who wish to be registered as PIP recipients. Keywords: PIP Assistance Recipient; AHP Method; PHP and MySQL. Abstrak: Tahun 2014 pemerintah membuat Program Indonesia Pintar (PIP) yang menjadi bagian penyempurnaan Bantuan Siswa Miskin. PIP merupakan bantuan dari pemerintah untuk masyarakat miskin dalam hal pendidikan yang diberikan kepada keluarga dengan anak usia sekolah (6-21 tahun) berasal dari keluarga miskin. Pihak Sekolah Dasar Negeri 010069 Desa Punggulan berkewajiban untuk mendaftarkan siswanya yang mempunyai KIP ke Dapodik supaya bisa segera mendapat manfaat PIP. Kendala yang dihadapi oleh pihak SDN 010069 Desa Punggulan adalah terdapat banyak kriteria yang harus diperhitungkan sehingga kesulitan dalam menentukan prioritas calon penerima PIP. Untuk mengatasi permasalahan tersebut perlu adanya sistem dalam menentukan prioritas calon penerima PIP dengan menambahkan beberapa kriteria yang lebih mendasar. Pada penelitian ini dirancang sistem pendukung keputusan menggunakan metode AHP (Analitycal Hierarchy Process) dengan beberapa kriteria yaitu Status Aktif Siswa, Surat Keterangan Miskin, Kondisi Yatim Piatu, Gaji Orang Tua, Presentasi Absensi. Pada aplikasi ini didapatkan hasil akhir berupa perankingan prioritas siswa yang akan menerima bantuan PIP. Berdasarkan permasalahan tersebut maka dapat diambil kesimpulan bahwa banyaknya kriteria bagi siswa miskin yang tidak memiliki KIP, menyulitkan pihak SDN 010069 Desa Punggulan dalam menentukan prioritas siswa miskin yang ingin didaftarkan sebagai penerima PIP. Kata kunci : Penerima Bantuan PIP; Metode AHP; PHP dan MySQL