bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study on the dispersion performance and mechanism of polycarboxylate superplasticizer by the long side‐chain dicarboxyl terminated
Authors: Li Zhenzhong , Zhou Tianfeng , Liu Hai , Jin Yu , Pang Yuxia , Lou Hongming , Yang Dongjie , Qiu Xueqing 
Published: April 2023

AbstractThe steric hindrance formed by polyether side chains is the key factor determining the dispersion performance of polycarboxylate superplasticizer (PCE). While with the increase of the side chain length, the coiled conformation of side chain will prevent the dispersion ability of PCE from being further improved. In this work, the methallyl polyoxyethylene ether (HPEG) was esterified with tricarballylic acid (TA) to obtain dicarboxyl terminated macromonomer, and further used to synthesize polycarboxylate (PCETA). The fluidity tests show that compared with ordinary PCE‐B2400 with short side chain, the dispersion performance of PCETA‐2400 was slightly improved. While for the PCEs with long side chain, the dispersion ability of PCETA‐4000 was significantly improved than that of ordinary PCE‐B4000. The adsorption layer thickness of PCETA‐4000 adsorbed on the surface of SiO2 sphere measured by dynamic light scattering is 7.93 nm, which is 1.3 times that of PCE‐B4000. Due to electrostatic repulsion between the carboxylic groups, the stretching of long side‐chain forms stronger steric hindrance and enhancing the dispersion of cement particles. In addition, PCETA also shows good slump retention and clay resistance properties, and it is an excellent multi‐functional concrete admixture with great application potential.
Microbubble on fiber method to determine the contact angle between steel substrates and highly viscous molten PEKK and PA 6
Authors: Chen Kuan , Chu Liangyong , Grouve Wouter J. B. , de Vries Erik G. , Akkerman Remko , Bao Ningzhong , de Rooij Matthijn B. 
Published: April 2023

AbstractDetermining the contact angle between a molten thermoplastic and a solid is important for the processing of thermoplastics and their composites. The well‐known sessile drop method can be used to determine the contact angle of thermoplastics. However, complex instrumental systems are needed due to the high viscosity and high melting point of thermoplastics. Inspired by the captive bubble method, a simple method based on the system of an air bubble on a substrate in the molten thermoplastic was proposed. This system is prepared by melting fibers and thermoplastic powder materials mixtures in between two glass plates using a hot stage. The contact angle of a microbubble in contact with fiber in molten thermoplastic is measured using an optical microscope. The system of a microbubble in molten thermoplastic can easily reach the equilibrium state. Two types of highly viscous thermoplastics in contact with stainless steel fibers are studied and the contact angle is sensitive to both the physicochemical properties of the fiber surface and the type of polymer matrix materials, which demonstrates the applicability of this method. Our proposed method is promising to be further developed into a general method to determine the contact angle between thermoplastics and solid surfaces.
A thermoresponsive hydrogel with a wide‐range tunable phase transition temperature triggered by small molecules
Authors: Wang Jian , Sun Wen , He Ming 
Published: April 2023

AbstractThermoresponsive polymer hydrogels have great potential in the fields of smart window and information encryption due to the drastic changes in transmittance caused by the phase transition at specific temperatures. The synthesis of thermoresponsive hydrogels with a wide range and sensitive temperature response is current research goal. Here, we demonstrate a polymethacrylamide (PMAAm) hydrogel with the upper critical solution temperature (UCST) ranging from 62 to −1°C by simply polymerizing the monomer in different concentrations of acetic acid (Ac) solutions. The hydrogel exhibits sensitive temperature response with a temperature hysteresis within 2°C and can maintain stable transmittance changes after 200 cycles of testing. The phase transition mechanism is revealed by combining ultraviolet visible spectra, differential scanning calorimetry, Fourier transform infrared spectra, dynamic light scattering and scanning electron microscope measurements. This thermoresponsive hydrogel can be applied in smart window and information encryption. The smart window prepared with the hydrogel had a very high ΔTlum (The luminous transmittance modulation, 94.4%), ensuring daytime illumination and privacy protection at night. Meanwhile, the smart window exhibits an excellent thermal insulation capability for energy‐saving buildings. The hydrogels with different UCST are flexibly combined to display designed patterns at different temperatures, demonstrating the ability of the hydrogels to be used for information encryption.
Optimizing the dielectric and mechanical properties of melamine based‐benzoxazine resin by copolymerizing with epoxy resin
Authors: Ye Jiajia , Fan Zilin , Zhang Shuai , Liu Xiaobo 
Published: April 2023

AbstractBenzoxazine resins are suffering from high curing temperature, low crosslinking density, and poor toughness, which hampers their broad applications. The introduction of melamine during synthesis has been shown useful in improving these properties, but the dielectric property was deteriorated heavily. Epoxy resins show higher crosslinking density and better toughness but the thermal properties are relatively poor. Herein, the melamine based‐benzoxazine MBF was copolymerized with epoxy resin E51 in this work in order to improve the dielectric properties. The curing reactivity, polymerization mechanism and the comprehensive properties such as thermal, dielectric and mechanical properties were systematically verified. It is found that the abundant active functional groups such as amino and phenolic groups in MBF could catalyze and copolymerize with E51 and form uniform copolymers poly(MBF‐E) at various proportions. With the increasing of epoxy resins, more polar amino groups was consumed, thus the polarity and the water absorption of the copolymers decreased. Additionally, the dielectric constant decreased from 3.67 for poly(MBF) to 2.94 for poly(MBF‐60E). Meanwhile, the highest increasement of tensile strength and elongation at break value reached 130% and 70%, respectively, which may be caused by the higher crosslinking density and more flexible ether bond formed.
In Situ Synthesis of Amorphous GeSe/CNT Composite via Defective‐carbon‐mediated Chemical Bonding for Ultrastable Na Ion Storage
Authors: Lee Geon‐Woo , Kim Young Hwan , Choi Song‐Gue , Choi Hun Seok , Kim Kwang‐Bum 
Published: April 2023

AbstractHerein, we report the in‐situ synthesis of amorphous GeSe/CNT composite via defective‐carbon‐mediated chemical bonding for ultrastable Na‐ion storage. Structural defects in CNTs play a crucial role in the chemical bonding and bonding strength in GeSe/CNTs composites. Specifically, the bonding strength tends to increase with increasing defect concentrations of CNTs. Remarkably, the strong chemical bonding between GeSe and CNTs significantly weakens Ge−Se bonds and promotes amorphization of GeSe, thus facilitating a reversible conversion reaction and enhancing Na‐ion diffusion. Consequently, GeSe/CNTs composite exhibits outstanding cyclability of 87.9% even after 1000 cycles at 1 A g−1and a high‐rate capability of 288.3 mA h g−1at 10 A g−1. Our work presents a promising approach for the amorphization of electrode materials enabled by the defective‐carbon‐mediated strong chemical bonding for Li‐, Na‐, and K‐ion batteries.
Shaping Public Perception: Polish Illustrated Press and the Image of Polish Naturalists Working in Latin America, 1844–1885
Authors: Kaye Aleksandra 
Published: April 2023

AbstractThis article will investigate the ways in which Polish illustrated press contributed to communicating and reporting the work of Polish émigré naturalists working in Latin America to the Polish general public living in the Prussian, Russian and Austrian partitions of the Polish‐Lithuanian Commonwealth 1844–1885. It examines the ways in which illustrations were used to shape the public's opinion about the significance of these migrants’ scientific achievements. The Polish illustrated press, its authors and editors were instrumental in shaping the public's perceptions of the reach of Polish scientists, and exploring their impact on broader scientific debates, thereby situating Polish people and their work in a global context. The didactic and opinion‐making role of the illustrated press was highly influential among Polish audiences during this period, at a time when the survival of Polish identity, culture, language, and education was uncertain. Illustrated weeklies were one of the vectors through which high science was made accessible to the Polish public. A study of pictures in Polish illustrated press will help to explain how they contributed towards shaping the images in the public eye of naturalists’ scientific work, and discourses about science and its actors more broadly.
White light emission and energy transfer of LaMgAl11O19:Eu3+, Tb3+ phosphors
Authors: Li Tingting , Pang Jiali , Xue Chaolumen , Sha Ren 
Published: April 2023

AbstractWhite‐light‐tunable LaMgAl11O19:x%Tb3+, y%Eu3+ series phosphors were prepared using the gel‐combustion method. The structure and luminescence properties were studied, and the energy transfer of Eu3+ and Tb3+ in the LaMgAl11O19 system was also discussed. The results showed that the LaMgAl11O19 matrix exhibited strong emission in the blue‐light region under the excitation of ultraviolet light, which resulted in conditions suitable for the preparation of white‐light‐tunable phosphors. The emission spectra of LaMgAl11O19:2%Tb3+, y%Eu3+ (y = 2%–9%) series phosphors were obtained through optimization experiments. It could be seen from the CIE diagram that by adjusting the doping quantities of Eu3+ and Tb3+ in the LaMgAl11O19 host, multicolor luminescence and white light emission in a single host could be achieved. By calculating the energy transfer efficiency and critical distance between Eu3+ and Tb3+ series phosphors, the mechanism of energy transfer between Tb3+ and Eu3+ was found to be the interaction between electric quadruples.
Mimotope discovery as a tool to design a vaccine against Zika and dengue viruses
Authors: Cuevas‐Juárez Esmeralda , Liñan‐Torres Arturo , Hernández Carolina , Kopylov Mykhailo , Potter Clint S. , Carragher Bridget , Ramírez Octavio T. , Palomares Laura A. 
Published: April 2023

AbstractVaccine development against dengue virus is challenging because of the antibody‐dependent enhancement of infection (ADE), which causes severe disease. Consecutive infections by Zika (ZIKV) and/or dengue viruses (DENV), or vaccination can predispose to ADE. Current vaccines and vaccine candidates contain the complete envelope viral protein, with epitopes that can raise antibodies causing ADE. We used the envelope dimer epitope (EDE), which induces neutralizing antibodies that do not elicit ADE, to design a vaccine against both flaviviruses. However, EDE is a discontinuous quaternary epitope that cannot be isolated from the E protein without other epitopes. Utilizing phage display, we selected three peptides that mimic the EDE. Free mimotopes were disordered and did not elicit an immune response. After their display on adeno‐associated virus (AAV) capsids (VLP), they recovered their structure and were recognized by an EDE‐specific antibody. Characterization by cryo‐EM and enzyme‐linked immunosorbent assay confirmed the correct display of a mimotope on the surface of the AAV VLP and its recognition by the specific antibody. Immunization with the AAV VLP displaying one of the mimotopes induced antibodies that recognized ZIKV and DENV. This work provides the basis for developing a Zika and dengue virus vaccine candidate that will not induce ADE.
Synthesis and Cytotoxicity Studies of Br‐Substituted Salphen Organic Compounds
Authors: Zelada‐Guillén Gustavo A. , Ríos‐Arce Jesús A. , Leyva‐Peralta Mario A. , Flores‐Álamo Marcos , Gálvez‐Ruíz Juan Carlos , Calderón Kadiya , Escárcega‐Bobadilla Martha V. 
Published: April 2023

AbstractWe present the synthesis and characterization of organic Salphen compounds containing bromine substituents at the para/ortho‐para positions, in their symmetric and non‐symmetric versions, and describe the X‐ray structure and full characterization for the new unsymmetrical varieties. We report for the first time antiproliferative activity in metal‐free brominated Salphen compounds, by evaluations in four human cancer cell lines, cervix (HeLa), prostate (PC‐3), lung (A549) and colon (LS 180) and one non‐cancerous counterpart (ARPE‐19). We assessed in vitro cell viability against controls using the MTT assay ((3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyl‐2H‐tetrazolium bromide)) and determined the concentration required for 50 % growth inhibition (IC50), together with their selectivity vs. non‐cancerous cells. We found promising results against prostate (9.6 μM) and colon (13.5 μM) adenocarcinoma cells. We also found a tradeoff between selectivity (up to 3‐fold vs. ARPE‐19) and inhibition, depending upon the symmetry and bromine‐substitution of the molecules, showing up to 20‐fold higher selectivity vs. doxorubicin controls.
Comparison of Protective Effect of Aqueous and Ethanolic Extracts of Propolis against Gastric Ulceration in Rats
Authors: Sahin Huseyin , Kaltalioglu Kaan , Erisgin Zuleyha , Coskun‐Cevher Sule , Kolayli Sevgi 
Published: April 2023

AbstractThis study focused on the protective effects of different types of propolis extracts on gastric mucosa in indomethacin‐induced rats. The animals were divided into nine groups: control, negative control (ulcer), positive control (omeprazole), and experimental groups, which were summarized by 200, 400, and 600 mg/kg, bw for aqueous‐based and ethanol, respectively. According to the histopathological evaluation, more than others, the doses of 200 and 400 mg/kg of aqueous‐based propolis extracts had different degrees of positive effects on the gastric mucosa. Generally, the biochemical analyses of the gastric tissue showed a correlation with microscopic evaluations. According to the phenolic profile analysis, while pinocembrin (684.34±1.70 μg/ml) and chrysin (540.54±9.06 μg/ml) were the most abundant phenolics in the ethanolic extract, ferulic acid (53.77±0.07 μg/ml) and p‐coumaric acid (52.61±0.42 μg/ml) dominated the aqueous‐based extract. Also, the total phenolic content (TPC), total flavonoid content (TFC), and DPPH radical scavenging activity of the ethanolic extract showed almost nine‐fold superiority compared to the aqueous‐based extracts. Based on data from preclinical data, it was decided that the best doses for the main goal of the study were 200 mg and 400 mg/kg, bw for aqueous‐based propolis extract.
Catalytic and Sustainable Amide Bond Formation using a DABCO/Dichlorotriazine System
Authors: Adler Pauline , Gras Marion , Smietana Michael 
Published: April 2023

AbstractAmides are one of the most important functional groups in organic chemistry and play essential roles in both the pharmaceutical industry and life sciences. However, due to the natural reactivity of carboxylic acids and amines, their direct coupling is challenging and often leads to reactions that are not atom‐economic and produce large amounts of non‐recoverable by‐products. Despite the impressive number of coupling reagents available, sustainable methods for amide bond formation are still needed. To address this challenge, a new catalytic approach for the direct preparation of amides from carboxylic acids and amines is reported here. This method combines organocatalysis with a substoichiometric amount of activating agent under mild conditions (open air, room temperature, green solvents). This method was applied with good efficiency on a wide range of substrates, without epimerization of chiral stereocenters and on SPPS.
Design, Synthesis, and Biological Evaluation of Histone Deacetylase Inhibitors Derived from Erianin and Its Derivatives
Authors: Yang Yawen , Liu Qingqing , Wang Xinyi , Gou Shaohua 
Published: April 2023

AbstractMulti‐target histone deacetylase (HDAC) inhibitors can be designed by introducing dominant structures of natural products to enhance activity and efficacy while avoiding the toxicity from other targets. In this study, we reported a series of novel HDAC inhibitors based on erianin and amino erianin upon pharmacophore fusion strategy. Two representative compounds, N‐hydroxy‐2‐(2‐methoxy‐5‐ (3,4,5‐trimethoxyphenethyl)phenoxy)acetamide and N‐Hydroxy‐8‐((2‐methoxy‐5‐ (3,4,5‐trimethoxyphenethyl)phenyl)amino)octanamide, possessed good inhibitory effect against five cancer cells tested (IC50=0.30–1.29 μΜ, 0.29–1.70 μΜ) with strong HDAC inhibition, and low toxicity toward L02 cells, which were selected for subsequent biological studies in PANC‐1 cells. They were also found to promote the intracellular generation of reactive oxygen species, cause DNA damage, block the cell cycle at G2/M phase, and activate the mitochondria‐related apoptotic pathway to induce cell apoptosis, which are significant for the discovery of new HDAC inhibitors.
An adaptive link training based hybrid circuit topology for full‐duplex on‐chip interconnects
Authors: Govindaswamy Prema Kumar , Kammari Raviteja , Pasupureddi Vijaya Sankara Rao 
Published: April 2023

SummaryThis work proposes a link training based half‐rate dynamic current‐steering echo‐cancellation hybrid circuit topology for full‐duplex signaling that performs echo cancellation by deploying a bit error detection unit and backchannel adaptation. In addition, this work proposes a power‐efficient half‐rate dynamic current‐steering logic hybrid circuit for full‐duplex signaling over on‐chip interconnects for simultaneous transmission and reception. The half‐rate dynamic current‐steering hybrid circuit topology has low static power consumption compared with traditional current‐mode circuit topology implementations, thanks to the discrete nature of the current‐steering hybrid topology. The proposed scheme is implemented in 1.2 V, 65‐nm complementary metal‐oxide semiconductor (CMOS). The performance results show that the link training scheme sets the control bits for both the transmitter driver and hybrid circuit topology when the backchannel adaptation loop gets locked for 1‐ and 3‐mm interconnects for process, voltage, and temperature (PVT) variations. The proposed hybrid circuit topology is able to receive the required far‐end transmitted data with the link training scheme and has the differential recovered received signal voltage swing of 1.2 V for both 1‐ and 3‐mm interconnect at the 10‐Gb/s data rate. The total power consumption of the hybrid is 3 and 3.5 mW for 1‐ and 3‐mm interconnect with an energy efficiency of 0.6 and 0.7 pJ/bit, respectively, at 10‐Gb/s full‐duplex operation.
Sensory impairment and algorithmic classification of early cognitive impairment
Authors: Cai Yurun , Schrack Jennifer A. , Gross Alden L. , Armstrong Nicole M. , Swenor Bonnielin K. , Deal Jennifer A. , Lin Frank R. , Wang Hang , Tian Qu , An Yang , Simonsick Eleanor M. , Ferrucci Luigi , Resnick Susan M. , Agrawal Yuri 
Published: April 2023

AbstractINTRODUCTIONSensory impairment (SI) is linked to cognitive decline, but its association with early cognitive impairment (ECI) is unclear.METHODSSensory functions (vision, hearing, vestibular function, proprioception, and olfaction) were measured between 2012 and 2018 in 414 Baltimore Longitudinal Study of Aging (BLSA) participants (age 74 ± 9 years; 55% women). ECI was defined as 1 standard deviation below age‐, sex‐, race‐, and education‐specific mean performance in Card Rotations or California Verbal Learning Test immediate recall. Log binomial models (cross‐sectional analysis) and Cox regression models (time‐to‐event analysis) were used to examine the association between SI and ECI.RESULTSCross‐sectionally, participants with ≥3 SI had twice the prevalence of ECI (prevalence ratio = 2.10, p = 0.02). Longitudinally, there was no significant association between SI and incident ECI over up to 6 years of follow‐up.DISCUSSIONSI is associated with higher prevalence, but not incident ECI. Future studies with large sample sizes need to further elucidate the relationship between SI and ECI.Highlights
Sensory impairment is associated with high prevalence of early cognitive impairment
Multisensory impairment may pose a strong risk of early changes in cognitive function
Identifying multisensory impairment may help early detection of dementia
Determination of the Time since Deposition of blood‐traces in a forensic context: Application of untargeted LC‐HR‐MS/MS metabolomics profiling
Authors: Schneider Tom Dario , Kraemer Thomas , Steuer Andrea Eva 
Published: April 2023

AbstractBeing able to attest when a bloodstain was deposited at a crime scene can be invaluable to a prosecution process, and methods to provide that information have long been desired. Determining the Time since Deposition (TsD) of a trace would allow placing a subject both in space and time to the crime scene—or prove that a trace left by that person was unrelated to it because it was deposited before or after the time the crime had occurred. To this day, no method for TsD determination has made its way into routine forensic casework, mainly because of the numerous challenges that await when trying to understand and account for all the influencing and confounding factors that affect the aging process (such as, e.g., temperature, UV‐light exposure, or humidity). Here, we present an untargeted metabolomics‐based study using liquid chromatography high‐resolution mass spectrometry (LC‐HR‐MS) and data‐dependent acquisition to analyze blood samples aged under two distinctly different storage conditions over 48 weeks. Global differences in age‐ and storage‐dependent changes in blood metabolomes were described, and TsD‐classification strategies based on qualitative and quantitative assessment of molecular features (MFs) have been proposed. Based on the selected criteria to best predict the TsD, the dipeptide Phenylalanylalanine (PheAla) can be considered as a promising candidate for TsD prediction. In essence, changes in the blood metabolome dynamics showed a strong association with increasing TsD, but significant differences depending on storage conditioning were observed, facilitating the need to study further the influence of individual influencing factors on TsD determination.
Investigation of the Thermal Properties of Alkali Metal Thorium Phosphates and Their Application for the Sorption of Uranyl Ion from Acidic Medium
Authors: Patkare Geeta , Shafeeq Muhammed , Sengupta Arijit , Keskar Meera , Phatak Rohan , Kannan Shanmugaperumal 
Published: April 2023

AbstractThermo physical properties of potassium, rubidium and cesium thorium phosphate compounds were investigated. All compounds were synthesized by conventional solid state method. Formation of orthorhombic AMThP3O10, tetragonal AM2Th(PO4)2 and monoclinic AMTh2(PO4)3; [AM=K, Rb and Cs] was confirmed using Powder X‐ray diffraction (XRD) technique. Structural study of CsThP3O10 was carried out for the first time from Rietveld refinement of XRD data. Thermal stability of all compounds was established using Thermogravimetric analysis (TGA) technique. When heated at 1673 K for 30 h in air, all the compounds decompose to ThO2. High temperature X‐ray diffraction (HT‐XRD) data of the compounds, synthesized during present study, were collected in an inert atmosphere from ambient to 973 K and their thermal expansion coefficients were calculated. These compounds show positive thermal expansion up to 973 K. Molar heat capacities for all phosphates were measured between 300–863 K using Differential Scanning Calorimeter. Alkali metal thorium phosphates, AMThP3O10 and AMTh2(PO4)3, showed efficient uptake of uranyl ion from aqueous acidic medium predominantly following Langmuir isotherm and Webber Morris intra particle diffusion kinetics.