bluuebunny/crossref_metadata_2025_split huggingface dataset:
Larval habitat suitability and landscape genetics of the mosquito Anopheles coluzzii on São Tomé and Príncipe islands
Authors: Chamberland Lisa , Campos Melina , Corrêa Maria , Pinto João , Cornel Anthony J. , Viegas João , Lanzaro Gregory C. 
Published: February 2025

Abstract

Context
This study was conducted to contribute to the design of a field trial of a novel genetic strategy aimed at the elimination of malaria. The strategy involves the introduction, establishment and spread of a gene construct into natural populations of the malaria vector Anopheles coluzzii on the African islands of São Tomé and Príncipe (STP). The gene construct renders the mosquito incapable of transmitting the parasite. Understanding the ecology of this mosquito is an essential component of the STP trial design. Identifying landscape features that define the target mosquito’s distribution, understanding connectivity among subpopulations and estimating population stability in the face of climate change are critical factors contributing to the field trial.

Objectives
STP provides an ideal study site to isolate and identify the role of potentially influential environmental factors in mosquito vector distributions across heterogeneous landscapes, critical information for the design of a GEM field trial. In this study we aim to quantify the relative influence of biotic and abiotic environmental factors on Anopheles coluzzii larval habitat suitability and if environmental variables promote or restrict gene flow between local populations.

Methods
We used an ecological niche modeling (ENM) approach to test the relationship between environmental variables and A. coluzzii larval occurrences within the islands of STP. We implemented high-resolution spatial models of both current and future larval distributions under a range of climate change scenarios. We assessed functional connectivity of A. coluzzii in STP using circuit theory-based approaches to identify environmental variables impeding or promoting gene flow.

Results
Results from the ENM revealed higher habitat suitability in the northeastern regions of both islands, characterized by higher human population densities and lower elevations. Habitat suitability under future climate projection models predicted minimal range expansions on STP, even under a ‘business-as-usual’ model. There was a signal of isolation-by-resistance on São Tomé, with roads promoting gene flow and higher elevation restricting gene flow.

Conclusions
This study provides a clearer understanding of the role of climate, topography and human activity on A. coluzzii larval habitat suitability and underscores the importance of considering both current and future climate projections to establish robust baseline data. Additionally, the role of roads in facilitating gene flow of this species will not only be essential to the design of GEM field trials, but will contribute to our understanding of malaria epidemiology in the islands and to improving ongoing vector control programs.
On the Harmonic Characterization Of The Spheres: A Sharp Stability Inequality
Authors: Cupini Giovanni , Lanconelli Ermanno 
Published: February 2025

Abstract
Let D be a bounded open subset of

$$\mathbb {R}^n$$

R

n

with finite

$$(n-1)$$

(
n
-
1
)

-dimensional Hausdorff measure

$$|\partial D|$$

|
∂
D
|

and let

$$x_0 $$

x
0

be a point of D. We introduce a new harmonic invariant, that we call Kuran gap of

$$\partial D$$

∂
D

w.r.t.

$$x_0$$

x
0

. To define this new invariant, denoted

$$\mathcal {K}(\partial D, x_0)$$

K
(
∂
D
,

x
0

)

, we use a family of harmonic functions introduced by Kuran (Bull. London Math. Soc. 4, 311-312, 1972). Our main stability result can be described as follows: if

$$\partial D$$

∂
D

is sufficiently regular just in one of the points of

$$\partial D$$

∂
D

nearest to

$$x_0$$

x
0

, then

$$\mathcal {K}(\partial D, x_0)$$

K
(
∂
D
,

x
0

)

is bounded from below by a kind of isoperimetric index, precisely the normalized difference between

$$|\partial D|$$

|
∂
D
|

and

$$|\partial B|$$

|
∂
B
|

, being B the biggest ball contained in D and centered at

$$x_0$$

x
0

. This partially extends and improves a stability result by Preiss and Toro. By our stability result, we also obtain new rigidity results: (i) a characterization of the Euclidean spheres in terms of single-layer potentials, improving previous theorems by Fichera and by Shahgholian; (ii) a sufficient condition for a harmonic pseudosphere to be a Euclidean sphere, partially extending and improving rigidity results by Lewis and Vogel.
New data on land molluscs from Sicily and biogeographical considerations
Authors: Liberto Fabio , Corso Andrea , Gregorini Armando , Colomba Mariastella 
Published: February 2025

Abstract
This paper is devoted to discussing new records of land molluscs from Sicily and the surrounding archipelagos (Italy) acquired during our survey in the field in the last twenty years (2004–2024). Monacha parumcincta, a species widespread in Kérkira Island (Greece) and Apennine Italy, is reported for the first time in northeastern Sicily; Sardovitrina polloneriana, up to now considered endemic to Sardinia Island (Italy), is recorded for the first time from Pantelleria Island and Linosa Island (Sicilian Channel); Aegopinella pura, a species with European distribution, is confirmed in Sicily on the summit part of the Madonie Mountains (northern Sicily); and Milax lopadusanus, recently described from Lampedusa Island (Pelagian Archipelago, Sicily), is here reported also for Marettimo Island (Aegadian Archipelago, Sicily). The species identification is based on morphological inspection of shells and genitalia. Taxonomy and biogeographic issues are discussed as well.
New evidence that blueberry (Vaccinium spp.) has floral traits that enable pollination at night
Authors: Buxton Max N. , Gaskett Anne C. , Lord Janice M. , Pattemore David E. 
Published: February 2025

Abstract
The role of nocturnal pollinators has been globally understudied, particularly in agriculture, but growing evidence suggests that crops often assumed to be pollinated during the day also receive additional pollination by night-active animals. In our study, we assessed six different types of evidence to determine whether blueberry flowers, which are typically associated with diurnal pollinators, could also be pollinated at night. We used observational and experimental approaches commonly used and validated for assessing nocturnal pollination, including variation in stigma receptivity and pollen viability at day and night, nectar standing crop dynamics, temporal effects of pollen germination, pollinator exclusion experiments and the presence of pollen on the bodies of potential nocturnal pollinators (moths). Stigma receptivity and pollen viability were similar between our day and night sample points. We found no negative effects of time of pollination on pollen germination. Nectar availability was strongly associated with time of day, and although nectar was available both day and night, nectar volume was highest at night. Fruit set was highest in flowers with unrestricted access to pollinators, but we are unable to determine the relative importance of nocturnal versus diurnal pollination as these treatments gave the same result as our control. Moths caught in blueberry orchards carried pollen from 25 plant species, with blueberry pollen being the fifth most abundant. Our results show that blueberry flowers have floral traits that allow pollination at night as well as during the day, and that moths, along with other nocturnal insects, may be contributing to this. However, the importance of nocturnal pollination relative to diurnal pollination remains unknown.
Audit of VTE prophylaxis prescribing preferences among orthopaedic consultants in Irish orthopaedic trauma centres
Authors: Timon Charles , Kilkenny Conor , Byrne Nicola , Quinlan John F. , McGoldrick Niall P. 
Published: February 2025

Abstract

Background
Thromboembolic complications are common in trauma orthopaedic practise. Despite extensive research, there remain a number of unanswered questions regarding the use of thromboprophylaxis.

Aims
To establish the current practise among Irish consultant orthopaedic surgeons regarding thromboprophylaxis.

Methods
A confidential online questionnaire regarding VTE prophylaxis was circulated to all consultant orthopaedic surgeons in training hospitals in the Republic of Ireland. Questions investigated surgeon awareness of local/national guidelines, inpatient and outpatient prescribing preferences and agreement/disagreement with the statement that defensive medicine, rather than evidence-based medicine, has driven increased emphasis on VTE prophylaxis in Ireland in recent years.

Results
The response rate was 72% (69/96). 72% (50/79) of surgeons were aware of local VTE prophylaxis guidelines. 38% (29/96) were aware of national guidelines. 89% (62/69) routinely used mechanical prophylaxis modalities. 73.9% (51/69) routinely used chemical prophylaxis for inpatients. However, this practise was z extremely heterogenous with five other pharmacological agents used by the remainder. 82.6% (57/69) routinely discharged patients on extended duration chemical prophylaxis. 67% (46/69) agreed that the recent increased emphasis on VTE prophylaxis was due to defensive medicine and not evidence-based medicine.

Conclusion
The results of this survey show that venous thromboembolism is regarded as a significant complication of orthopaedic surgery and most orthopaedic surgeons actively try to prevent it. There was a higher rate of intervention compared to previous surveys of Irish orthopaedic surgeons, possibly reflecting surgeon concerns regarding the high rate of litigation nationally. However, there is no consensus as to the optimum therapy which reflects the conflicting evidence available in the many publications on this subject.
Bullying Victimization and Subjective Well-Being in 10- and 12-year-Old Children from 24 Countries: The Buffering Effect of Family and Teacher Support
Authors: Oriol Xavier , Miranda Rafael , Varela Jorge , Garcia Nuria 
Published: February 2025

Abstract
Bullying victimization in children is a recognized public health concern in many countries worldwide. Specifically, studies have consistently demonstrated that bullying victimization is one of the indicators that most significantly and negatively influences the subjective well-being (SWB) of children. Following this assumption, a study was conducted to examine the impact of bullying victimization on subjective well-being among 75,877 students aged 10 and 12 years across 24 countries. Additionally, the moderating role of support from teachers and family members in the relationship between bullying victimization and subjective well-being was investigated using structural equation modeling (SEM) analysis. The results show that, in many countries, there is an interaction effect of both family support and teacher support figures in both age groups (10 and 12 years). However, significant variability in these interaction effects was observed across countries, and in some countries, no moderating effect was detected. Specifically, in the 12-year-old group, a larger number of countries show no interaction effect from any adult support figure in the relationship between bullying victimization and SWB. The findings are discussed with a focus on the buffering effects of both types of support, the variability observed across countries, and the practical implications of these results.
Lifestyle Habits, Problem Behaviors and Non-Suicidal Self-Injury in Adolescents: A Systematic Review with Meta-Analysis of Longitudinal Studies
Authors: Goñi-Sarriés Adriana , Gutiérrez-Valencia Marta , Morata-Sampaio Leticia , Saiz-Fernández Luis C. , Leache-Alegría Leire , Sánchez-Villegas Almudena 
Published: February 2025

Abstract
Some lifestyle habits and problematic behaviors have been associated to non-suicidal self-injury (NSSI) in adolescents in cross-sectional studies but their role as individual risk factors needs to be analyzed through proper longitudinal designs. The objective is to analyze and summarize the evidence on the association of lifestyle habits and problem behaviors with NSSI in adolescents. Longitudinal studies were searched in Medline, Embase and APA PsycInfo without date or language restrictions. Adolescents with and without exposure factors were compared. Out of 5295 identified records, 13 longitudinal studies were included (39,575 participants). Studies included different age ranges (10–20 years, mean 14.3, SD 2.4), and 78% were female. Results showed a statistically significant increased risk of NSSI with regular smoking, alcohol use, early cannabis use, and poor physical activity. Inconsistent results were found for use of technology and sleep habits, and no studies analyzed dietary habits or gambling. Most studies were of moderate or high quality but certainty of the evidence was very low according to GRADE criteria. Longitudinal evidence suggests that some lifestyle habits and problem behaviors are risk factors for NSSI in adolescents. These findings highlight the importance of developing strategies to promote healthy lifestyles in adolescents.
Chinweizu’s Vision: Unveiling the Complexities of Pan-Africanism and African Sovereignty
Authors: Atimniraye Nyelade Richard 
Published: February 2025

Abstract
The paper critically revisits Chinweizu’s contributions to Pan-Africanism and African sovereignty, focusing on his analysis of Arab and Western imperialism, internal complicity, and the concept of “culturecide.” His call for a distinct Black African identity is explored as a foundation for reclaiming sovereignty, while also addressing critiques of nativism and essentialism. A nuanced approach to decolonization is proposed, emphasizing its relevance in today’s globalized world. Chinweizu’s ideas challenge a rethinking of the intersections between history, culture, and power in the ongoing quest for African autonomy.
Latine Aspirational Status and Support for the January 6 Insurrection
Authors: Ocampo Angela X. , Ocampo-Roland Angie N. , Uribe Laura 
Published: February 2025

Abstract
Henry “Enrique” Tarrio—the former Afro-Latino leader of the Proud Boys, a right-wing extremist group—positioned himself as a prominent leader of the January 6 insurrection. Our current understanding of Latine politics, and ethnoracial politics more broadly, would call this a striking paradox. Tarrio’s views highlight that Latines’ view of their place in the ethnoracial hierarchy can vary. We argue that an understudied phenomenon, aspirational status, particularly on ethno-cultural and socioeconomic dimensions, can help us understand variation in Latines’ attitudes and behaviors. While some Latines may adopt a minoritized status and align themselves closer to ethnoracial minorities, others may align themselves closer to whites. We explore how these forms of aspirational status, as well as racial resentment, impact Latines’ political attitudes toward the January 6 insurrection. Using the 2020 Collaborative Multiracial Post-Election Survey (CMPS), we find that Latines who aspire to a higher ethno-cultural status that approximates whiteness, as well as those who aspire to a higher socioeconomic status and who distance themselves from Black Americans, are more likely to be supportive of the insurrection. This paper contributes to the overall understanding of the heterogeneity of Latine political attitudes and illustrates the role of status in shaping political attitudes among Latines.
Domination vs. Persuasion: The Role of Libido Dominandi in Adam Smith’s Thought
Authors: Santori Paolo 
Published: February 2025

Abstract
Adam Smith argued that human beings naturally desire to dominate others and that they enjoy it. He showed how ancient masters, landlords, and economic actors in some eighteenth-century English and colonial markets were driven by their love of domination against their own economic interests. Recent scholarship argues that to fully understand the role libido dominandi plays in Smith’s thought, love of domination should be associated with the broader concept of vanity and esteem-seeking. This article challenges that interpretation, showing that, for Smith, the love of domination has nothing to do with the love of praise but that most of the pleasure people derive from it is to see their ends promoted by others without the need to persuade them about the utility of those ends. This understanding locates the love of domination outside commercial society where, under certain socio-economic circumstances, mutual persuasion among individuals is the rule.
The connectedness of Sierpiński sponges with rotational and reflectional components and associated graph-directed systems
Authors: RUAN HUO-JUN , XIAO JIAN-CI 
Published: February 2025

Abstract
We provide two methods to characterise the connectedness of all d-dimensional generalised Sierpiński sponges whose corresponding iterated function systems (IFSs) are allowed to have rotational and reflectional components. Our approach is to reduce it to an intersection problem between the coordinates of graph-directed attractors. More precisely, let

$(K_1,\ldots,K_n)$

be a Cantor-type graph-directed attractor in

${\mathbb {R}}^d$

. By creating an auxiliary graph, we provide an effective criterion for whether

$K_i\cap K_j$

is empty for every pair of

$1\leq i,j\leq n$

. Moreover, the emptiness can be checked by examining only a finite number of geometric approximations of the attractor. The approach is also applicable to more general graph-directed systems.
Pacific Controls the Co‐Occurrence of Extreme Positive Indian Ocean Dipole and the Following Summer Tropical Indian Ocean Basin‐Wide Warming
Authors: Tang Shaolei , Luo Jing‐Jia , Zhang Zhiyuan 
Published: February 2025

AbstractThe extreme positive Indian Ocean Dipole (pIOD) in 2019 was followed by tropical Indian Ocean (TIO) basin‐wide warming in summer 2020, which contributed to severe flooding in the Yangtze River basin. Here, the potential relationship between extreme pIOD and subsequent summer TIO basin‐wide warming is explored using observations and model outputs, revealing that this sequential co‐occurrence is significantly influenced by Pacific SST conditions. Extreme pIODs that coincide with El Niño tend to be followed by TIO basin‐wide warming, whereas those cooccurring with neutral or La Niña conditions are comparatively less likely to do so. This is because El Niño can trigger anomalous anticyclone over the southeastern TIO, thereby maintaining and reinforcing the extreme pIOD‐related warm SST anomalies over the southwestern TIO, which subsequently induces SST warming over the northern TIO in summer. Our findings highlight the important modulation role of Pacific SST conditions, with significant implications for regional climate predictions.
Increasing Large Precipitation Events and Low Available Water Holding Capacity Create the Conditions for Dry Land‐Atmosphere Feedbacks in the Northeastern United States
Authors: Jurado Samuel , Matthes Jackie 
Published: February 2025

AbstractAs a warmer climate enables an increase in atmospheric humidity, extreme precipitation events have become more frequent in the Northeastern United States. Understanding the impact of evolving precipitation patterns is critical to understanding water cycling in temperate forests and moisture coupling between the atmosphere and land surface. Although the role of soil moisture in evapotranspiration has been extensively studied, few have analyzed the role of soil texture in determining ecosystem‐atmosphere feedbacks. In this study, we utilized long term data associated with ecosystem water fluxes to deduce the strength of land‐atmosphere coupling at Harvard Forest, Petersham, MA, USA. We found a 1.5% increase in heavy precipitation contribution per decade where high‐intensity events compose upwards of 42% of total yearly precipitation in 2023. Intensifying precipitation trends were found in conjunction with a long‐term soil drying at the Harvard Forest despite no significant increase in evapotranspiration over 32 years. This suggests that soil water holding capacity is a key mediating variable controlling the supply of water to ecosystems and the atmosphere. We found that these land surface changes directly impacted the lifted condensation level (LCL) height over Harvard Forest which was found to be increasing at a rate of 6.62 m per year while atmospheric boundary layer (ABL) heights have fallen at a modest rate of 1.76 m per year. This has amplified dry feedbacks between the land surface and the atmosphere such that 80% of observed summers ending in a water deficit also had an anomalously low soil water content in the spring.
Systemic HER3 ligand-mimicking nanobioparticles enter the brain and reduce intracranial tumour growth
Authors: Alonso-Valenteen Felix , Mikhael Simoun , Wang HongQiang , Sims Jessica , Taguiam Michael , Teh James , Sances Sam , Wong Michelle , Miao Tianxin , Srinivas Dustin , Gonzalez-Almeyda Nelyda , Cho Ryan H. , Sanchez Romny , Nguyenle Kimngan , Serrano Erik , Ondatje Briana , Benhaghnazar Rebecca L. , Gray Harry B. , Gross Zeev , Yu John , Svendsen Clive N. , Abrol Ravinder , Medina-Kauwe Lali K. 
Published: February 2025

Abstract
Crossing the blood–brain barrier (BBB) and reaching intracranial tumours is a clinical challenge for current targeted interventions including antibody-based therapies, contributing to poor patient outcomes. Increased cell surface density of human epidermal growth factor receptor 3 (HER3) is associated with a growing number of metastatic tumour types and is observed on tumour cells that acquire resistance to a growing number of clinical targeted therapies. Here we describe the evaluation of HER3-homing nanobiological particles (nanobioparticles (NBPs)) on such tumours in preclinical models and our discovery that systemic NBPs could be found in the brain even in the absence of such tumours. Our subsequent studies described here show that HER3 is prominently associated with both mouse and human brain endothelium and with extravasation of systemic NBPs in mice and in human-derived BBB chips in contrast to non-targeted agents. In mice, systemically delivered NBPs carrying tumoricidal agents reduced the growth of intracranial triple-negative breast cancer cells, which also express HER3, with improved therapeutic profile compared to current therapies and compared to agents using traditional BBB transport routes. As HER3 associates with a growing number of metastatic tumours, the NBPs described here may offer targeted efficacy especially when such tumours localize to the brain.