bluuebunny/crossref_metadata_2025_split huggingface dataset:
Detection of antibiotic-resistant bacteria and resistance genes SHV, TEM, and CTX-M in drinking waters in Tehran, Iran
Authors: Atharinia Masomeh , Safaeian Shila , Rahimifard Nahid , Nadoshen Rezvan Mosavi , Pourakbari Babak 
Published: April 2023

Abstract
Nowadays, a difficult problem has been disrupting people's health through treated and untreated water, namely the existence of antibiotic-resistant bacteria in these environments. The first is such organisms’ ability to acquire resistance genes through genetic elements, and the second seems to be the substances’ potential toxicity. The health index of supply water is lacking for bacteria such as coliform bacteria, Escherichia coli, Pseudomonas aeruginosa, and intestinal enterococci. The study's main aim was to figure out how these bacteria function as antibiotic resistance pools, not only to find resistant genes like SHV, TEM, and CTX-M but also to depict the dendrogram of clones in water supply samples in Tehran. Over the course of a year, 17 strains of P. aeruginosa were analyzed. In this study, 94.1% of the isolates tested positive for the TEM gene, while only one isolate tested positive for the CTX-M gene, and none tested positive for the SHV gene. This research shows that P. aeruginosa is not as common in drinkable water as previously thought. Nevertheless, it appears that P. aeruginosa can spread acquired antibiotic resistance vertically rather than horizontally.
From waste-activated sludge to algae: a self-reliant cultivation process in photoreactors using saline conditions
Authors: Cao Jinhua , Wang Keli , Chen Fanzhen , Li Cheng , Gu Yue , Fang Zheng , Wang Hao , Lu Jingfang , Meng Fansheng , Huang Wenli , Liu Dongfang , Wang Shaopo 
Published: April 2023

Abstract
In this study, microalgae–bacteria (MB) systems using saline conditions (3 and 5% salinity) were built in order to use waste-activated sludge (AS) as raw material for cultivating lipid-rich microalgae. Algae were observed to be flourishing in 60 days of operation, which totally used the N and P released from the sludge biomass. A prominent improvement of lipid content in MB consortia was obtained under algae growth and salinity stimulation, which occupied 119–136 mg/g-SS rather than a low content of 12.1 mg/g-SS in AS. Lipid enrichment also brought a 3.1–3.3 times total heat release (THR) in the MB biomass. The marine spherical algae Porphyridium, as well as filamentous Geitlerinema, Nodularia, Leptolyngbya were found to be the main lipid producers and self-flocculated to 23.0% (R1) and 33.5% (R2) volume under the effect of residue EPS. This study had a big meaning in not only waste sludge reduction but also in manufacturing useful bioenergy products.
A Novel Low Molecule Peptides-calcium Chelate from Silkworm Pupae Protein
Hydrolysate: Preparation, Antioxidant Activity, and Bioavailability
Authors: Xun Xiao-Meng , Zhang Zhi-Ang , Yuan Zi-Xuan , Tuhong Kamila , Yan Cheng-Hai , Zhan Yu-Fan , He Si-Jie , Liu Shun-Hui , Kang Guo-Ping , Wang Jun 
Published: April 2023

Background:
The antioxidant properties of active peptides from silkworm pupae protein hydrolysate
are of interest, and it serves as a novel source of calcium supplement.

Methods:
Optimize the preparation parameters of silkworm pupae bioactive peptide-calcium chelate, and investigate
the mechanism and bioavailability of silkworm pupae active peptide as a transport carrier to promote calcium
ion absorption using simulated gastrointestinal digestion and Caco-2 monolayer cell model.

Results:
The optimal process parameters for preparing peptide calcium chelate were the peptide calcium mass
ratio of 3:1, pH of 6.7, a temperature of 35.6°C, and time of 32.8 min by Box-Behnken design, and the calciumchelating
rate reached 84.67%. The DPPH radical scavenging activity of silkworm pupae protein hydrolysatecalcium
chelate was 79.36 ± 4.31%, significantly higher than silkworm pupae protein hydrolysate (61.00 ±
9.56%). Fourier transform infrared spectroscopy shows that the COO-, N-H, C-H, and C-O groups participated
in the formation of silkworm pupae protein hydrolysate-calcium chelate. The particle size of the silkworm pupae
protein hydrolysate-calcium chelate was 970.75 ± 30.12 nm, which was significantly higher than that of
silkworm pupae protein hydrolysate (253.14 ± 5.72 nm). The silkworm pupae protein hydrolysate-calcium chelate
showed a calcium dissolution rate of 71.01 ± 1.91% in the simulated intestinal phase, significantly higher
than that of CaCl2 (59.34 ± 1.24%). In the Caco-2 cell monolayers, the silkworm pupae protein hydrolysatecalcium
chelate was more favorable for calcium transport.

Conclusion:
A novel silkworm pupa protein hydrolysate-calcium chelate with high antioxidant activity was
successfully prepared to improve the bioavailability of calcium.
Bumetanide, a Diuretic That Can Help Children with Autism Spectrum
Disorder
Authors: Shaker Esraa , Agami Osama El , Salamah Abeer 
Published: April 2023

Background:
Autism Spectrum Disorder (ASD) is a common child neurodevelopmental
disorder, whose pathogenesis is not completely understood. Until now, there is no proven treatment
for the core symptoms of ASD. However, some evidence indicates a crucial link between this disorder
and GABAergic signals which are altered in ASD. Bumetanide is a diuretic that reduces chloride,
shifts gamma-amino-butyric acid (GABA) from excitation to inhibition, and may play a significant
role in the treatment of ASD.

Objective:
The objective of this study is to assess the safety and efficacy of bumetanide as a treatment
for ASD.

Methods:
Eighty children, aged 3-12 years, with ASD diagnosed by Childhood Autism Rating Scale
(CARS), ⩾ 30 were included in this double-blind, randomized, and controlled study. Group 1 received
Bumetanide, Group 2 received a placebo for 6 months. Follow-up by CARS rating scale was performed
before and after 1, 3, and 6 months of treatment.

Results:
The use of bumetanide in group 1 improved the core symptoms of ASD in a shorter time with
minimal and tolerable adverse effects. There was a statistically significant decrease in CARS and most
of its fifteen items in group 1 versus group 2 after 6 months of treatment (p-value <0.001).

Conclusion:
Bumetanide has an important role in the treatment of core symptoms of ASD.
Feministisch gedachtegoed in de sexploitatiefilm. Een genderanalyse van Stephanie Rothmans The Working Girls (1974)
Authors: Van Wijmeersch Ophelia 
Published: April 2023

Het beruchte en hypermannelijke sexploitatie genre, een vorm van lagere budget-films, stond in de jaren zestig en zeventig enorm bekend om de erotische en ondergeschikte weergave van de vrouw. Dit artikel illustreert aan de hand van de feministische sexploitatiefilm The Working Girls (1974) hoe Stephanie Rothman als een van de weinige vrouwelijke regisseurs toch feministische boodschappen kon verwerken in de patriarchale filmindustrie van de jaren zeventig. English abstract: The infamous and hyper-masculine sexploitation genre, a form of lower-budget films, was hugely known in the 1960s and 1970s for its erotic and subordinate portrayal of women. This article uses the feminist sexploitation film The Working Girls (1974) to illustrate how Stephanie Rothman, as one of the few female directors, was still able to incorporate feminist messages into the patriarchal film industry of the 1970s.
Pemanfaatan dan Modifikasi Limbah Plastik untuk Perbaikan Sifat Teknik (Kuat-Geser) Tanah Lempung
Authors: Endaryanta Endaryanta , Eksana Wibowo Dian 
Published: April 2023

ABSTRACTThis study aims to determine: (1) the value of unconfined compressive strength (qu) clay mixed shredded plastic waste serrated; (2) the value of the internal friction angle (φ) soil mixed shredded plastic waste serrated; (3) the value of soil friction (c) soil mixed shredded plastic waste serrated. This study used an experimental method. Plastic waste is cut by the jagged edges 1x1 cm and 1x0,5 cm then mixed in clay, compacted, and then tested robust free press and direct shear. Clay samples taken at elevation -0.30 m of area from Punukan Kulon Progo and Kasongan Bantul. Waste plastics using a former mineral water containers (plastic types PET). The results showed that the addition of pieces of plastic waste that size on clay will: (1) raise the value of the unconfined compressive strength (qu) of land at the rate of plastic 3% clay Kasongan, and if pieces of plastic rather large 1x1 cm on clay Wates (2) increase the internal friction angle (φ) if the levels of plastic 3% (clay Kasongan) and on clay Wates but only if the plastic is cut rather large 1x1 cm. (3) Soil frictionis going up at the rate of 2% plastic (clay Kasongan), raise the coherence, clay Wates if the plastic pieces small size 0,5x1 cm.Keywords: clay, direct shear, free press, waste plasticsABSTRAKPenelitian ini bertujuan untuk mengetahui: (1) nilai kuat-tekan bebas (qu) tanah lempung yang dicampur cacahan limbah plastik bergerigi; (2) nilaisudut gesek intern (φ) tanah yang dicampur cacahan limbah plastik bergerigi; (3) nilai lekatan (c) tanah yang dicampur cacahan limbah plastik bergerigi. Penelitian ini menggunakan metode eksperimen. Limbah plastik dipotong-potong secara tepi bergerigi ukuran 1x1 cm dan 1x0,5 cm kemudian dicampurkan pada tanah lempung, dipadatkan, lalu diuji kuat tekan bebas dan geser langsung. Sampel lempung diambil pada elevasi -0,30 m dari daerah Punukan Kabupaten Kulonprogo dan Kasongan Kabupaten Bantul. Limbah plastik menggunakan bekas wadah air mineral (plastik jenis PET).Hasil penelitian menunjukkan bahwa penambahan potongan limbah plastik ukuran tersebut pada lempung akan: (1) menaikkan nilai kuat tekan bebas (qu) tanah pada kadar plastik 3% lempung Kasongan, dan jika potongan plastiknya agak besar 1x1cm pada lempung Wates (2) menaikkan sudut-kuat-geser (φ) jika kadar plastik 3% (lempung Kasongan) dan pada Lempung Wates tetapi hanya jika plastiknya dipotong agak besar 1x1cm. (3) lekatan akan naik pada kadar plastik 2% (lempung Kasongan), menaikkan lekatan, Lempung Wates jika potongan plastik ukuran kecil 0,5x1cm.Kata kunci: geser langsung, lempung, limbah plastik, tekan-bebas.
PEMANFAATAN ABU SABUT KELAPA SAWIT DAN PENGARUHNYA TERHADAP KARAKTERISTIK BATAKO
Authors: Jalali Nur Aisyah 
Published: April 2023

ABSTRACT This study aims to determine the physical properties and quality of the concrete block that contain palm ash as a partial replacement of cement.The sample of concrete blocks measuring 40x20x10 cm with compositions 1 cement and 4 sand (volume ratio).Variations of the test specimen without palm ash and containing palm ash content with 5%, 10%, 15%, and 20% of the cement used.The test includes examining the size, the compressive strength testing, and water absorption.The test results showed that the length and width of the concrete blocks are still in the allowable limits, but the thickness does not meet standards. The results of compressive strength testing of concrete blocks with ash content 5%, 10%, and 15% are considered quality II, concrete blocks without ash and with ash content of 20% included in the quality III. The test results of water absorption for all variations of the mixture into the quality I and II Keywords: concrete block, palm fiber, measure, strength, water absorption ABSTRAK Penelitian ini bertujuan untuk mengetahui sifat-sifat fisis dan mutu batako akibat adanya abu sabut kelapa sawit (SKS) sebagai bahan pengganti sebagian semen. Benda uji berupa batako berukuran 40x20x10 cm dengan komposisi 1 semen dan 4 pasir (perbandingan volume). Variasi benda uji yakni batako tanpa abu SKS, dan batako dengan abu SKS sebesar 5%, 10%,15%, serta 20% dari kebutuhan semen. Pengujian meliputi pemeriksaan ukuran, pengujian kuat tekan, dan penyerapan air. Hasil pemeriksaan ukuran menunjukkan bahwa panjang dan lebar batako masih berada dalam batas yang diperkenankan, tetapi tidak demikian dengan tebal batako. Hasil pengujian kuat tekan batako dengan kadar abu 5%, 10%, dan 15% masuk dalam mutu II, sedangkan batako tanpa kadar abu dan batako dengan kadar abu 20% masuk dalam mutu III (Balitbang Kimpraswil, 2003b). Hasil pengujian penyerapan air untuk semua variasi campuran masuk dalam mutu I dan II (Balitbang Kimpraswil, 2003b). Kata kunci: batako, sabut kelapa sawit, ukuran, kuat tekan, penyerapan air.
IDENTIFIKASI KEGAGALAN PELAKSANAAN CRASH PROGRAM DALAM PROYEK KONTRUKSI
Authors: Bawono Setiono Eko 
Published: April 2023

ABSTRACTCrash program becomes an alternative solution for the implementation of construction projects that are faced with limit time. In practice, the crash program is not easy to implement considering the two main requirements must be fulfilled: 1) the number of available resources is not an obstacle and 2) if the desired time of completion is completed faster with the same scope, then the resource requirements will increase. This study aims to identify the factors that cause failure of crash program implementation in construction project. Quantitative and qualitative approaches are carried out simultaneously in analyzing secondary data and primary data. Weekly progress achievement as secondary data and primary data such as respondent (owner, head of construction management, project manager, and site manager) interview reports. The result of the analysis shows that the failure of crash program implementation is caused by three main factors: 1) materials unavailability, 2) inadequate human resources and 3) lack of achievement of specification.Keywords: crash program, construction projectABSTRAKCrash program menjadi alternatif solusi bagi pelaksanaan proyek konstruksi yang dihadapkan pada waktu pelaksanaan yang sangat sempit. Dalam pelaksanaannya, crash program tidak mudah dilaksanakan mengingat dua persyaratan utama harus terpenuhi yaitu:1) jumlah sumber daya yang tersedia tidak merupakan kendala dan 2) bila diinginkan waktu penyelesaian kegiatan lebih cepat dengan lingkup yang sama, maka keperluan sumber daya akan bertambah. Penelitian ini bertujuan mengidentifikasi faktor-faktor penyebab kegagalan pelaksnaan crash program dalam proyek konstruksi. Pendekatan kuantitatif dan kualitatif dilakukan secara bersamaan dalam menganalisa data sekunder dan data primera. Data sekunder berupa capaian progress mingguan dan data primer berupa interview responden (Owner, pimpinan manajemen konstruksi, project manager, dan site manager). Hasil analisa menunjukkan bahwa kegagalan pelaksanaan crash program disebabkan oleh tiga faktor utama yaitu: 1) ketidaktersediaan material, 2) SDM yang tidak memadai dan 3) kurangnya pencapaian spesifikasi.Kata kunci: crash program, proyek konstruksi
STUDI PERBANDINGAN RANCANG CAMPUR BETON NORMAL MENURUT SNI 03-2834-2000 DAN SNI 7656:2012
Authors: Santoso Agus , Darmono Darmono , Ma'arif Faqih , H Sumarjo 
Published: April 2023

ABSTRACTThis study examines the design of normal concrete mixtures according to SNI 03-2834-2000 and SNI 7656: 2012. This research is done because SNI 7656: 2012 is an adoption of ACI 211 which requires a mixture considering its economic side. This research was conducted by experimental method in laboratory. In this research, the test object used is concrete cylinder with dimension 150 x 300 mm. The test specimen consists of 2 variants, namely: normal concrete SNI 2000 (BN-00), and normal concrete SNI 2012 (BN-12). Each variant consists of 3 strong compressive specimen plans: 25 MPa, 30MPa, and 35 MPa. Based on the result of the test, it is found that the strength of concrete with the design of SNI 2000 for the compressive strength of 25 MPa (BN-00-25), 30 MPa (BN-00-30) and 35 MPa (BN-00-35) 27.24 MPa, 38.99 MPa, and 44.85 MPa. While the concrete mean press with the design of SNI 2012 for the compressive strength of 25 MPa (BN-12-25), 30 MPa (BN-12-30), and 35 MPa (BN-12-35) plans were 31,43 MPa , 36.54 MPa, and 39.76 MPa. Keywords: mixed design, SNI 03-2834-2000, SNI 7656: 2012, compressive strength ABSTRAKMakalah ini mengkaji tentang rancang campur beton normal menurut SNI 03-2834-2000 dan SNI 7656:2012. Dilakukannya kajian ini karena SNI 7656:2012 merupakan adopsi dari ACI 211 yang mensyaratkan suatu campuran dengan mempertimbangkan sisi ekonomisnya. Kajian ini dilakukan dengan metode eksperimen di laboratorium. Pada kajian ini benda uji yang digunakan adalah silinder beton dengan dimensi 150 x 300 mm. Benda uji terdiri dari 2 varian yaitu : beton normal SNI 2000 (BN-00), dan beton normal SNI 2012 (BN-12). Tiap varian terdiri dari 3 spesimen kuat tekan rencana yaitu: 25 MPa, 30MPa, dan 35 MPa. Berdasarkan hasil pengujian didapatkan kuat tekan rerata beton dengan rancangan SNI 2000 untuk kuat tekan rencana 25 MPa (BN-00-25), 30 MPa (BN-00-30), dan 35 MPa (BN-00-35) berturut-turut sebesar 27,24 MPa, 38,99 MPa, dan 44,85 MPa. Sedangkan tekan rerata beton dengan rancangan SNI 2012 untuk kuat tekan rencana 25 MPa (BN-12-25), 30 MPa (BN-12-30), dan 35 MPa (BN-12-35) berturut-turut sebesar 31,43 MPa, 36,54 MPa, dan 39,76 MPa. Kata kunci: rancang campur, SNI 03-2834-2000, SNI 7656:2012, kuat tekan
PERFORMANCE BASED DESIGN BANGUNAN GEDUNG UNTUK LEVEL KINERJA OPERASIONAL
Authors: Ertanto Boby Culius , Satyarno Iman , Suhendro Bambang 
Published: April 2023

ABSTRACT Indonesia is an area with high earthquake risk, where earthquake-resistant design is required, in critical category IV buildings such as hospitals and educational buildings must be designed to remain operation during and after the earthquake design, without significant damage. owners have the ability to establish and know the performance levels of structures designed with performance-based design methods that impact on development costs, repair costs and reduce casualties due to earthquakes. there are two performance based design methods namely pushover and nonlinear history of time (NLTHA). with ductility values of μ 3 or R 4.8 and Ie 1.5, the structures are designed to have an opertional (O) performance during the earthquake design (DBE) and immediate occupancy (IO) during a maximum earthquake (MCE). using acceptance according to the capacity spectrum method, element acceptance limit and drift according to FEMA 356.Keyword: operational, ductility, performance based design ABSTRAK Indonesia merupakan daerah dengan resiko gempa tinggi, dimana dibutuhkan perencanaan tahan gempa, pada bangunan penting kategori IV seperti rumah sakit dan gedung pendidikan harus didesain tetap beroperasi saat dan setelah terjadinya gempa rencana, tanpa mengalami kerusakan yang signifikan. Pemilik memiliki kemampuan untuk menetapkan dan mengetahui level kinerja dari struktur yang didesain dengan metode performance based design yang berdampak pada biaya pembangunan, biaya perbaikan dan mengurangi korban jiwa akibat gempa. Dimana terdapat dua metode performance based design yaitu pushover dan nonlinier riwayat waktu (NLTHA). Dari penggunaan nilai daktilitas sebesar μ 3 atau R 4.8 dan Ie 1.5, struktur yang didesain memiliki kinerja opertional (O) saat terjadinya gempa rencana (DBE) dan immediate occupancy (IO) saat terjadi gempa besar (MCE). Dengan menggunakan penerimaan menurut capacity spectrum method, batas penerimaan elemen dan drift menurut FEMA 356. Kata Kunci: operasional, ductility, performance based design
A Risk Prediction Model for Physical Restraints Among Older Chinese Adults in Long-term Care Facilities: Machine Learning Study
Authors: Wang Jun , Chen Hongmei , Wang Houwei , Liu Weichu , Peng Daomei , Zhao Qinghua , Xiao Mingzhao 
Published: April 2023

Background
Numerous studies have identified risk factors for physical restraint (PR) use in older adults in long-term care facilities. Nevertheless, there is a lack of predictive tools to identify high-risk individuals.

Objective
We aimed to develop machine learning (ML)–based models to predict the risk of PR in older adults.

Methods
This study conducted a cross-sectional secondary data analysis based on 1026 older adults from 6 long-term care facilities in Chongqing, China, from July 2019 to November 2019. The primary outcome was the use of PR (yes or no), identified by 2 collectors’ direct observation. A total of 15 candidate predictors (older adults’ demographic and clinical factors) that could be commonly and easily collected from clinical practice were used to build 9 independent ML models: Gaussian Naïve Bayesian (GNB), k-nearest neighbor (KNN), decision tree (DT), logistic regression (LR), support vector machine (SVM), random forest (RF), multilayer perceptron (MLP), extreme gradient boosting (XGBoost), and light gradient boosting machine (Lightgbm), as well as stacking ensemble ML. Performance was evaluated using accuracy, precision, recall, an F score, a comprehensive evaluation indicator (CEI) weighed by the above indicators, and the area under the receiver operating characteristic curve (AUC). A net benefit approach using the decision curve analysis (DCA) was performed to evaluate the clinical utility of the best model. Models were tested via 10-fold cross-validation. Feature importance was interpreted using Shapley Additive Explanations (SHAP).

Results
A total of 1026 older adults (mean 83.5, SD 7.6 years; n=586, 57.1% male older adults) and 265 restrained older adults were included in the study. All ML models performed well, with an AUC above 0.905 and an F score above 0.900. The 2 best independent models are RF (AUC 0.938, 95% CI 0.914-0.947) and SVM (AUC 0.949, 95% CI 0.911-0.953). The DCA demonstrated that the RF model displayed better clinical utility than other models. The stacking model combined with SVM, RF, and MLP performed best with AUC (0.950) and CEI (0.943) values, as well as the DCA curve indicated the best clinical utility. The SHAP plots demonstrated that the significant contributors to model performance were related to cognitive impairment, care dependency, mobility decline, physical agitation, and an indwelling tube.

Conclusions
The RF and stacking models had high performance and clinical utility. ML prediction models for predicting the probability of PR in older adults could offer clinical screening and decision support, which could help medical staff in the early identification and PR management of older adults.
Review Literatur Penilaian Rekod di Lembaga Arsip, Universitas, dan Warisan Budaya
Authors: Pramudyo Gani Nur , Mayesti Nina 
Published: April 2023

Penilaian berurusan dengan proses memilah dan memberikan nilai kepada rekod serta akuisisi dengan menambah dan menyimpan rekod secara permanen. Terdapat berbagai jenis metodologi penilaian yang dapat diterapkan oleh lembaga seperti pendekatan berbasis nilai, analisis fungsional dan model penilaian makro serta hibridisasi. Penilaian telah mendefinisikan peran dalam fungsi manajemen rekod dan informasi terkini selain penggunaannya untuk memilih bahan untuk pemeliharaan jangka panjang. Penilaian terjadi dalam konteks, bisa sederhana atau kompleks dan mungkin memiliki kekhasan yang berbeda dari satu lembaga. Penelitian ini bertujuan membahas kajian penilaian rekod di lembaga arsip, universitas dan warisan budaya dengan mereview literatur secara mendalam. Penilaian di lembaga berbeda menunjukkan keragaman lokus dan fokus penilaian. Penilaian dapat berfokus pada medium rekod, seperti kertas atau elektronik. Penelitian ke depan dapat membahas penilaian rekod dalam konteks kelembagaan swasta (private sector) dan dapat berfokus pada contoh rekod dan medium yang digunakan. Penggunaan sistem penilaian rekod, implementasi kebijakan dan aspek sosio teknis penilaian rekod.