bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of face‐based and voice‐based first impressions in a Chinese sample
Authors: Jiang Zhongqing , Li Dong , Li Zhao , Yang Yi , Liu Yangtao , Yue Xin , Wu Qi , Yang Hong , Cui Xiaolin , Xue Peng 
Published: July 2023

AbstractPeople often form first impressions of others based on face and/or voice cues. This study aimed to compare the first impressions formed under these two cues. First, we compared free descriptions based on face and voice cues and found differences in the content and frequency of the personality words. We then compiled three wordlists used for face‐based and voice‐based first impression evaluations separately or simultaneously. Second, using these wordlists, we compared face‐based and voice‐based first impression ratings and found that both had significant intra‐rater and inter‐rater reliability. However, using the mean of the actors' self‐rating and their acquaintance rating as the validity criterion, only the ratings of ‘ingenuous’ and ‘mature’ traits in the face‐based first impression evaluation were significantly correlated with the validity criterion. Factor analysis revealed that face‐based first impression had the dimensions of capability and approachability, while voice‐based first impression had capability, approachability and reliability. The findings indicate that stable first impressions can be formed by either face or voice cues. However, the specific composition of impressions will vary between the cues. These results also provide a foundation for studying first impressions formed by an integrated perception of voice and face cues.
Smart analysis of anxiety people and their activities using heterogeneous quasiperiodic process
Authors: Zhao Ludi , Guo Xuting , Song Guanpeng 
Published: July 2023

AbstractThe increase in anxiety levels worldwide can be described as a serious global health threat. Around 500 million people suffer from mental disorders and are suffering from depression, and other mental‐oriented disabilities. The new technological paradigms such as the Internet of Things (IoT) were employed for detecting, and treating these disorders, which are being proposed, developed, and provide new capabilities to detect, assess and care for anxious people. These possibilities lead to several issues that are identified, which relate to patient privacy and confidentiality, security challenges such as data security, and the organization of IoT systems. To rectify these issues, we implement the Smart analysis of anxious people and their activities using Heterogeneous computing with virtual sensing. This system consists of the health application featuring the technique of the internet of things, heterogeneous computing, Cognitive Quasiperiodic motion, and Pentagonal tiling. This system introduces the internet of things‐assisted smart analysis of anxiety against people with their activities. It performs the optimization analysis for improving the levels. The observational results focus on how to deal with the issues which were overcome in the analysis levels of the anxiety disorders, which show that time spent using the heterogeneous computing with the virtual sense proves more accuracy (92.3%), specificity (Degrees of anxiety severity by 20%), precision (Analysis of anxiety stress level by 65%), and recall (Anxiety chances percentile by 65.34%). The proposed model is simulated, and the outcomes are compared with the prevailing methods for evaluating the parameters like accuracy, end‐end‐end delay, energy consumption, network lifetime, and throughput.
Necrobiosis lipoidica in childhood: a review of literature with emphasis on therapy
Authors: Schiefer‐Niederkorn Anna , Sadoghi Birgit , Binder Barbara 
Published: July 2023

SummaryNecrobiosis lipoidica (NL) is a rare chronic granulomatous disease that manifests as sharply demarcated, telangiectatic, brownish‐red plaques with atrophic yellowish centers prone to ulceration and occurs predominantly on the shins. In children, NL is extremely rare, but resistance to therapy, troublesome cosmetic appearance, painful ulcerations, and possible development of squamous cell carcinoma in long‐persisting lesions are challenges during treatment. Our review includes 29 reports of NL in patients aged <18 years published from 1990 on PubMed, EMBASE, and Medline. The mean age of patients was 14.3 years, with a female predominance of 2 : 1 and a high prevalence of diabetes mellitus (80%). Data showed that potent topical steroids up to twice daily is the first‐line treatment. For refractory cases, therapy can be switched to tacrolimus. Ulcerations benefit from phase‐adapted wound care and anti‐inflammatory medical dressings such as medical honey. Adding hyperbaric oxygenation to local or systemic therapy in difficult‐to‐treat ulcerated lesions can be considered. Refractory cases may be switched to topical photochemotherapy or systemic treatment with TNF‐α inhibitors, systemic steroids (preferably in non‐diabetic patients), pentoxifylline, or hydroxychloroquine. Necrobiosis lipoidica in childhood is difficult to treat, with a treatment failure rate of 40%. Therefore, further research through patient registries is recommended.
Considering dispersal costs to understand fish community dissimilarity in a high‐gradient basin of North America
Authors: de Rezende Breno Laio Medeiros , Dala‐Corte Renato Bolson , Melo Adriano S. 
Published: July 2023

AbstractFreshwater fish metacommunities are best understood when considering the dendritic structure of riverine networks. The dendritic structure imposes restrictions to dispersal associated with the connectivity. Many structures restrict the movement of fish even more, such as dams and the terrain slope (dispersal costs). We investigated the influence of environmental predictors and dispersal costs on the beta diversity of freshwater fishes from the Upper Tennessee River using Generalised Dissimilarity Modelling (GDM). In addition, we tested the effects of asymmetrical dispersal costs (high costs for upstream dispersal) on the nestedness of native and non‐native fishes. Environmental predictors were more important than dispersal costs for explaining the overall fish dissimilarity in the GDM models, with the turnover capturing most of the explanation compared to the species richness difference. Dam heights were the most important dispersal cost variable in the GDM, mainly for species turnover. Overall dissimilarity of the native fish subset was better explained by environmental and dispersal variables than non‐native fish (20.03% vs. 8.41%). Considering the native species assemblage subset, dispersal cost related to maximum channel slope between pairs of sites and watercourse distance increased the nestedness of adjacent upstream–downstream sites, whereas those attributed to dams reduced the nestedness. The results support that dams increase overall dissimilarity in the native fish metacommunity of the Upper Tennessee basin, but also reduce the nestedness of adjacent sites. Our findings improve the knowledge on how mechanisms and processes associated with dispersal costs in watersheds under the effects of dams create patterns of dissimilarity and nestedness.
Differences in patient‐reported outcomes (PROs) by disease severity in light chain (AL) amyloidosis
Authors: D'Souza Anita , Szabo Aniko , Akinola Idayat , Finkel Muriel , Flynn Kathryn E. 
Published: July 2023

AbstractObjectiveTo assess the impact of organ involvement on patient‐reported outcomes (PROs) in light chain (AL) amyloidosis.MethodsPROs were evaluated using the KCCQ‐12, PROMIS‐29 + 2, and SF‐36 in individuals with AL amyloidosis. The 2004 Mayo system was used to stage disease and cardiac, neurologic, and renal involvement was considered. Global physical and mental health (MH) scores, physical function (PF), fatigue, social function (SF), pain, sleep, and MH domains were evaluated. Effect sizes between scores were measured using Cohen's d.ResultsOf 297 respondents, the median age at diagnosis was 60 years with 58% cardiac, 58% renal, and 30% neurologic involvement. Fatigue, PF, SF, and global physical health with PROMIS and SF‐36 discriminated the most by stage. Significant discrimination in PROMIS and/or SF‐36 was seen in PF, fatigue, and global physical health with cardiac involvement. For neurologic involvement, PF, fatigue, SF, pain, sleep, global physical, and MH with PROMIS and role physical, vitality, pain, general health, and physical component summary with SF‐36 were discriminatory. For renal amyloid, pain by SF‐36 and PROMIS, and SF‐36 MH and role emotional subscales were significant.ConclusionsFatigue, PF, SF, and global physical health can discriminate stage, cardiac and neurologic, but not renal, AL amyloidosis involvement.
Experimental and computational studies of load ratio effect on fatigue crack growth rates in Alloy 709 at elevated temperatures
Authors: Ramirez Jose , Potirniche Gabriel P. , Shaber Nicholas , Stephens Robert , Charit Indrajit 
Published: July 2023

AbstractExperimental testing and finite element simulations of fatigue crack growth were performed in austenitic 20Cr‐25Ni (Alloy 709) steel at different load ratios and elevated temperatures. The experimental tests were performed using compact tension specimens, and crack growth rates were measured at stress intensity factors ranging between 5 and 35 MPa√m. Fractographic analysis using scanning electron microscopy indicated crack surface roughness and secondary cracking depending on testing temperature and load ratio. Finite element simulations of fatigue crack growth were performed to compute plasticity‐induced crack opening loads and predict crack growth rates. Predictions of fatigue crack growth rates using finite element simulations were performed using the computed crack‐tip opening loads, and they are shown to match well the experimental measurements.
COVID‐19 and the role of gender, earnings, and telecommuting in parents' employment
Authors: Scarborough William J. , Collins Caitlyn , Landivar Liana Christin , Ruppanner Leah , Huffman Matt L. 
Published: July 2023

AbstractObjectiveTo understand how married mothers' and fathers' earnings and ability to telecommute structured their employment throughout the COVID‐19 pandemic.BackgroundWe weigh two competing explanations—rational choice and gendered resources—to evaluate the association between married parents' financial and workplace resources and sustained employment throughout the pandemic.MethodWe use hierarchical logistic regression models to analyze rotating panel data from the current population survey for respondents in dual‐earner, different‐sex marriages who are aged 25 to 54 with children 12 years or younger from January 2020 through August 2021. We restrict our analysis to those who were employed prior to the start of the pandemic to isolate pandemic‐related exits.ResultsWe find that being the primary earner (i.e., earning at least half of the household income) prior to the start of the pandemic did not protect mothers from employment exits during the pandemic. Fathers' primary earner status did help sustain their employment. In contrast, access to telecommuting was an important resource to help sustain mothers' work attachment throughout the pandemic but had little association with fathers' employment.ConclusionRational choice explanations help explain married fathers' but not mothers' employment during the pandemic. Gendered resources better explain mothers' employment. Mothers who were primary earners were still pulled away from employment as caregiving demands grew during the pandemic. Telecommuting supported mothers' employment by offering flexibility in addressing these competing work and family demands, but not by challenging conventional gender divisions of labor among different‐sex couples.
Anatomical predictors of need for decompressive craniectomy after stroke using voxel‐based lesion symptom mapping
Authors: McCullough‐Hicks Margy , Topiwala Karan , Christensen Soren , Ruiz‐Betancourt Daniel , Mlynash Michael , Albers Gregory W. 
Published: July 2023

AbstractBackground and PurposeMalignant cerebral edema (MCE) secondary to ischemic stroke is a highly morbid condition. Decompressive craniectomy (DC) is the only treatment for MCE that has been shown to reduce mortality. We examined whether early infarction and/or hypoperfusion in specific topographic regions was predictive of the need for later DC.MethodsA retrospective database of patients evaluated for large vessel occlusion (LVO) stroke at Stanford between 2010 and 2019 was used. Thirty patients with LVO and baseline perfusion MRI who underwent DC were evaluated. Propensity matching based on age, lesion size, and recanalization status was performed on the remaining cohort. Baseline masks of apparent diffusion coefficient (ADC) + Tmax >6 seconds lesions were generated using automated perfusion software. Voxel‐based lesion symptom maping was used to perform logistic regression at each voxel to generate statistical maps of lesion location associated with DC. Hemispheres were combined to increase statistical power.ResultsSixty patients were analyzed. After adjusting for age, lesion size, and recanalization status as covariates, scattered cortical regions, predominately within the temporal and frontal lobe, were mildly to moderately predictive of the need for DC (z‐scores: 2.4‐6.74, p < .01).ConclusionsScattered temporal and frontal lobe regions on baseline diffusion and perfusion MRI were found to be mildly to moderately predictive of the need for subsequent DC in patients with LVO stroke.
Factors that influence family‐focused practice in Chinese mental health workers: A cross‐sectional survey
Authors: Yao Hao , Guan Lili , Zhou Tianhang , Zhang Changchun , Pan Yang , Han Jinxiang , He Rui , Chang Zhengjiao , Du Chunyu , Wu Tingfang , Sun Jingwen , Yuan Yilin , Maybery Darryl , Ma Hong 
Published: July 2023

AbstractIntroductionFamily‐focused practice has become an emerging paradigm in mental health services. However, little is known about family‐focused practice and associated factors in Chinese mental health workers.AimTo examine family‐focused practice and associated factors in Chinese mental health workers.MethodA cross‐sectional survey was conducted in a convenience sample of mental health workers (n = 515) in Beijing, China. The Family‐Focused Mental Health Practice Questionnaire was used to measure family‐focused practice, as well as worker, workplace and client factors that might influence family‐focused practice. Multiple linear regression analysis was performed to investigate the factors associated with family‐focused practice.ResultsOn average, the participants exhibited a moderate level of engagement in family‐focused practice. The factors that most significantly influenced family‐focused practice in Chinese mental health workers were skill and knowledge, worker confidence and time and workload. Moreover, psychiatrists were found to engage more in family‐focused practice than psychiatric nurses, and community mental health workers were more active in family‐focused practice than hospital‐based ones.DiscussionThis study provided important data concerning family‐focused practice and associated factors in Chinese mental health workers.Implications for PracticeThe varying level of Chinese mental health workers to engage in family‐focused practice has advocacy, training, research and organizational implications for mental health services in China and elsewhere.
Effects of head‐down tilt on optic nerve sheath diameter in healthy subjects
Authors: Ustick Jessica J. , Pardon Laura P. , Chettry Pratik , Patel Nimesh B. , Cheng Han 
Published: July 2023

AbstractPurposeIntracranial pressure increases in head‐down tilt (HDT) body posture. This study evaluated the effect of HDT on the optic nerve sheath diameter (ONSD) in normal subjects.MethodsTwenty six healthy adults (age 28 [4.7] years) participated in seated and 6° HDT visits. For each visit, subjects presented at 11:00 h for baseline seated scans and then maintained a seated or 6° HDT posture from 12:00 to 15:00 h. Three horizontal axial and three vertical axial scans were obtained at 11:00, 12:00 and 15:00 h with a 10 MHz ultrasonography probe on the same eye, randomly chosen per subject. At each time point, horizontal and vertical ONSD (mm) were quantified by averaging three measures taken 3 mm behind the globe.ResultsIn the seated visit, ONSDs were similar across time (p > 0.05), with an overall mean (standard deviation) of 4.71 (0.48) horizontally and 5.08 (0.44) vertically. ONSD was larger vertically than horizontally at each time point (p < 0.001). In the HDT visit, ONSD was significantly enlarged from baseline at 12:00 and 15:00 h (p < 0.001 horizontal and p < 0.05 vertical). Mean (standard error) horizontal ONSD change from baseline was 0.37 (0.07) HDT versus 0.10 (0.05) seated at 12:00 h (p = 0.002) and 0.41 (0.09) HDT versus 0.12 (0.06) seated at 15:00 h (p = 0.002); mean vertical ONSD change was 0.14 (0.07) HDT versus −0.07 (0.04) seated at 12:00 h (p = 0.02) and 0.19 (0.06) HDT versus −0.03 (0.04) seated at 15:00 h (p = 0.01). ONSD change in HDT was similar between 12:00 and 15:00 h (p ≥ 0.30). Changes at 12:00 h correlated with those at 15:00 h for horizontal (r = 0.78, p < 0.001) and vertical ONSD (r = 0.73, p < 0.001).ConclusionThe ONSD increased when body posture transitioned from seated to HDT position without any further change at the end of the 3 h in HDT.
Plasma cell‐free DNA concentration increases during luteolysis in beef cows
Authors: Lopez‐Duarte Maria Camila , Londoño Camila , Lasso Sergio , Heredia Daniella , Brown Morgan , DiLorenzo Nicolas , Pohler Ky , Gonella Angela 
Published: July 2023

AbstractDuring cell death, DNA is fragmented and reaches the bloodstream in the form of cell‐free DNA (cfDNA). Luteal cells must undergo an apoptotic process during structural luteolysis to begin a new oestrous cycle. We hypothesized that cfDNA concentrations would increase when inducing luteolysis by applying prostaglandin F2α (PGF2α) analog to the cycling cow. Multiparous non‐pregnant and non‐lactating Angus cows (Bos taurus; n = 15) were synchronized using the 7‐day CoSynch + CIDR protocol. Ten days after oestrus was detected, two treatments were applied (PGF2α, n = 10; or Con, n = 5). Twice a day, grey mode and colour Doppler ultrasonography were used to calculate area (CL‐A) and luteal blood perfusion (LBP%). Additionally, we collected one blood sample for plasma progesterone (P4) and cfDNA concentrations for four consecutive days. Data analysis was performed using the GLM procedure of SAS. The luteolysis induction was demonstrated by a decrease in P4 concentrations (p ≤ .01) and CL‐A (p ≤ .01) in the PGF2α group after 12 h of the PGF2α injection. Reduction of LBP% (p ≤ .01) in the PGF2α group after 36 h of the injection. The concentration of cfDNA showed a significant increase (p = .05) after 48 h of the PGF2α application in the PGF2α group. In conclusion, cfDNA showed a significantly increased concentration after luteolysis induction, which can imply that cfDNA could be used as a luteolysis biomarker in plasma.
Effect of a single warm compress prior to ophthalmic surgery on ocular surface and intraoperative visibility: a randomised controlled study
Authors: Ishikawa Sho , Yamaguchi Saori , Hashimoto Miho , Shinoda Kei 
Published: July 2023

PurposeWe investigated the effects of a warm compress immediately before surgery on the ocular surface and intraoperative visibility during surgery.MethodsA randomised controlled quasi-experiment at Saitama Medical University Hospital. From November 2020 to September 2021, 200 patients scheduled for endophthalmic surgery were randomly assigned to a group that received a hot compress with a spontaneously heating eye mask (HM group) or a group that received only an eye mask (control group). The eye masks were applied for 20 min from 2 hours before surgery, and before and after mask application in the non-invasive tear break-up time (NIBUT), tear meniscus height (TMH) and obstruction score of the meibomian gland (meiboscore) were evaluated. The time from wetting to dry blurring of the corneal surface (corneal blurring time, CBT) was also compared before and after the warm compress.ResultsWe enrolled 100 patients in the HM group (mean age 69.0±13.3 years) and 99 patients in the control group (mean age 69.5±16.2 years). In the control group, there were no significant changes in the NIBUT, meiboscore or TMH before and after eye mask use, whereas in the HM group, the NIBUT increased from 6.7±5.1 to 9.5±5.6 s (p<0.001), the meiboscore improved from 0.71±0.93 to 0.63±0.96 (p=0.03) and the TMH significantly improved from 0.22±0.08 to 0.24±0.08 mm (p<0.001). The CBT was longer the HM group than control group (33.5±13.4 s, 25.7±14.9 s, respectively, p=0.01).ConclusionsThe condition of the ocular surface and intraoperative visibility improved after a single warm compress.Trial registration numberUMIN R000047286.
STING mediates microglial pyroptosis via interaction with NLRP3 in cerebral ischaemic stroke
Authors: Li Wenyu , Shen Nan , Kong Lingqi , Huang Hongmei , Wang Xinyue , Zhang Yan , Wang Guoping , Xu Pengfei , Hu Wei 
Published: July 2023

BackgroundIschaemia-evoked neuroinflammation is a critical pathogenic event following ischaemic stroke. Gasdermin D (GSDMD)-associated pyroptosis represents a type of inflammation-associated programmed cell death, which can exacerbate neuroinflammatory responses and brain damage. Stimulator of interferon genes (STING) was recently described as a vital innate immune adaptor protein associated with neuroinflammation. Nevertheless, the regulatory effects of STING on microglial pyroptosis post-stroke have not been well elaborated.MethodsSTING-knockout and wild-type (WT) mice were subjected to middle cerebral artery occlusion (MCAO). STING small interfering RNA (siRNA) was transfected into BV2 cells before oxygen-glucose deprivation/reoxygenation (OGD/R). STING-overexpressing adeno-associated virus (AAV) and NOD-like receptor family pyrin domain containing 3 (NLRP3) siRNA were administered by stereotaxic injection. 2,3,5-Triphenyl tetrazolium chloride (TTC) staining, TdT-mediated dUTP nick end labeling (TUNEL) staining, Fluoro-Jade C (FJC) staining, neurobehavioural tests, immunohistochemistry, cytokine antibody array assay, transmission electron microscopy, immunoblot, Enzyme-linked immunosorbent assay (ELISA) and quantitative real-time polymerase chain reaction (qRT-PCR) were carried out. Co-immunoprecipitation assays were used to investigate the interplay between STING and NLRP3.ResultsSTING expression was increased after MCAO and mainly detected on microglia. STING deletion alleviated brain infarction, neuronal damage and neurobehavioural impairment in mice subjected to MCAO. STING knockout suppressed microglial activation and the secretion of inflammatory chemokines, accompanied by mitigation of microglial pyroptosis. Specific upregulation of microglial STING by AAV-F4/80-STING aggravated brain injury and microglial pyroptosis. Mechanistically, co-immunoprecipitation showed that STING bound to NLRP3 in microglia. Supplementation of NLRP3 siRNA reversed AAV-F4/80-STING-induced deterioration of microglial pyroptosis.ConclusionsThe current findings indicate that STING modulates NLRP3-mediated microglial pyroptosis following MCAO. STING may serve as a therapeutic target in neuroinflammation induced by cerebral ischaemic/reperfusion (I/R) injury.