bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of single and repeated doses of rivastigmine on gastric myoelectric activity in experimental pigs
Authors: Tsianou Chrysostomi Christina , Kvetina Jaroslav , Radochova Vera , Kohoutova Darina , Rejchrt Stanislav , Valis Martin , Zdarova Karasova Jana , Tacheci Ilja , Knoblochova Veronika , Soukup Ondrej , Bures Jan 
Published: June 2023

Background
Rivastigmine is a pseudo-irreversible cholinesterase inhibitor used for therapy of Alzheimer’s disease and non-Alzheimer dementia syndromes. In humans, rivastigmine can cause significant gastrointestinal side effects that can limit its clinical use. The aim of this study was to assess the impact of rivastigmine on gastric motor function by means of electrogastrography (EGG) in experimental pigs.

Methods
Six experimental adult female pigs (Sus scrofa f. domestica, hybrids of Czech White and Landrace breeds; 3-month-old; mean weight 30.7 ± 1.2 kg) were enrolled into the study twice and created two experimental groups. In group A, a single intragastric dose of 6 mg rivastigmine hydrogen tartate was administered in the morning to fasting pigs before EGG recording. In group B, rivastigmine was administered to overnight fasting animals in a dietary bolus in the morning for 7 days (6 mg per day). On day 8, an intragastric dose of 12 mg rivastigmine was given in the morning to fasting pigs before EGG. EGG recording was accomplished by means of an EGG standalone system. Recordings from both groups were evaluated in dominant frequency and EGG power (areas of amplitudes).

Results
In total, 1,980 one-minute EGG intervals were evaluated. In group A, basal EGG power (median 1290.5; interquartile range 736.5–2330 μV2) was significantly higher in comparison with the power of intervals T6 (882; 577–1375; p = 0.001) and T10 (992.5; 385–2859; p = 0.032). In group B, the dominant frequency increased significantly from basal values (1.97 ± 1.57 cycles per minute) to intervals T9 (3.26 ± 2.16; p < 0.001) and T10 (2.14 ± 1.16; p = 0.012), respectively. In group B, basal EGG power (median 1030.5; interquartile range 549–5093) was significantly higher in comparison with the power of intervals T7 (692.5; 434–1476; p = 0.002) and T8 (799; 435–1463 μV2; p = 0.004).

Conclusions
Both single as well as repeated intragastric administration of rivastigmine hydrogen tartrate caused a significant decrease of EGG power (areas of amplitudes) in experimental pigs. EGG power may serve as an indirect indicator of gastric motor competence. These findings might provide a possible explanation of rivastigmine-associated dyspepsia in humans.
Out Here: Anthology of Takatāpui and LGBTQIA+ Writers from Aotearoa, Chris Tse and Emma Barnes (eds) (2021)
Authors: Rodríguez-Salas Gerardo 
Published: June 2023

Review of: Out Here: Anthology of Takatāpui and LGBTQIA+ Writers from Aotearoa, Chris Tse and Emma Barnes (eds) (2021)
Auckland: Auckland University Press, 368 pp.,
ISBN 978 1 86940 931 9 (hbk), US$49.99
Tanna Times: Islanders in the World, Lamont Lindstrom (2021)
Authors: Rosier Morgane 
Published: June 2023

Review of: Tanna Times: Islanders in the World, Lamont Lindstrom (2021)
Honolulu, HI: University of Hawai‘i Press, 200 pp.,
ISBN 978 0 82488 667 7 (pbk), US$28
Imagining Decolonisation, Bianca Elkington, Moana Jackson, Rebecca Kiddle, Ocean Ripeka Mercier, Mike Ross, Jennie Smeaton and Amanda Thomas (2020)
Authors: Myllyntausta Mikko 
Published: June 2023

Review of: Imagining Decolonisation, Bianca Elkington, Moana Jackson, Rebecca Kiddle, Ocean Ripeka Mercier, Mike Ross, Jennie Smeaton and Amanda Thomas (2020)
Wellington: Bridget Williams Books, 184 pp.,
ISBN 978 1 98854 578 3 (pbk), NZ$17.99
Indigenous Textual Cultures: Reading and Writing in the Age of Global Empire, Tony Ballantyne, Lachy Paterson and Angela Wanhalla (eds) (2020)
Authors: Birk Hanne 
Published: June 2023

Review of: Indigenous Textual Cultures: Reading and Writing in the Age of Global Empire, Tony Ballantyne, Lachy Paterson and Angela Wanhalla (eds) (2020)
Durham and London: Duke University Press, 357 pp.,
ISBN 978 1 47801 081 4 (pbk), $29.95
Estrés megalopático y manía demiúrgica. Para una lectura de "La fuerte razón para estar juntos”, de Peter Sloterdijk
Authors: Fuentes Martín Sebastián 
Published: June 2023

En esta reseña se analizan las tesis más importantes desarrolladas por Peter Sloterdijk en La fuerte razón para estar juntos, publicado en español en el año 2022. La clave de lectura propuesta establece vinculaciones entre esta obra y los escritos del año 1993 —puntualmente, En el mismo barco y Extrañamiento del mundo—. Estas relaciones inter-textuales tienen por objeto contextualizar la afirmación central del ensayo: las sociedades contemporáneas son comunas auto-estresantes. A través de la reconstrucción general de esta idea, se presenta aquí una aproximación sistemática al modo particular en que Sloterdijk afronta el problema filosófico de la pertenencia y la identidad a la luz del significado que los nueve de noviembre tienen para la historia alemana.
Extension of the working time of dental composites due to a new type of white operating lamp
Authors: von Bülow Albrecht , Gente Ralf , Gente Michael 
Published: June 2023

Abstract

Objectives
Dental composite materials for filling teeth are usually hardened by polymerisation lamps emitting blue light. However, the same wavelength is also emitted by light of dental operating lamps for lighting the oral cavity. Thus, the hardening of the composite is already initiated earlier, shortening the time of formability. The objective of this study is to develop a specific white LED for dental operating lamps. When restoring teeth, it enables dentists to work longer on light-curing composites in the same brightness.

Methods
Based on a short-wave blue coloured LED and a fluorescent substance, a white luminescent LED with a colour temperature of approx. 3,000 K is produced as a prototype. The formable working times of three composites are measured for this LED and two dental head lamps at an illuminance of 10,000 lx.

Results
Shorter working times of 98–237 s were measured for the headlamps and 409–807 s for the new LED. This light of the new LED is perceived by the human eye as warm white.

Conclusions
The new LED extends the working time by the factor of 3.0 to 5.8 compared to the head lamps. This enables more precise modelling of fillings.
Learner autonomy and English achievement in Chinese EFL undergraduates: the mediating role of ambiguity tolerance and foreign language classroom anxiety
Authors: Chen Lilan 
Published: June 2023

Abstract
For Chinese EFL students, learning English has always been a great challenge, and research has shown that cognitive and affective factors increasingly become important issues in the field of foreign language learning and teaching (Naderifar and Esfandiari 2016). This study is designed to investigate the relationship between learner autonomy, ambiguity tolerance, foreign language classroom anxiety (FLCA) and English achievement. It also explores the inner mechanism of the relationship between learner autonomy and English achievement in Chinese EFL undergraduates. A sample of 291 third and fourth grade undergraduates in China was assessed for their levels of learner autonomy, ambiguity tolerance and foreign language anxiety using the Learner Autonomy Questionnaire (LAQ), Second Language Tolerance of Ambiguity Scale (SLTAS) and Foreign Language Classroom Anxiety Scale (FLCAS), respectively. Participants’ scores of the College English Test Band Four (CET-4) were used to measure their achievement in English. The results revealed a link between learner autonomy, ambiguity tolerance, FLCA, and English achievement. Ambiguity tolerance and FLCA mediated the relationship between learner autonomy and English achievement, accounting for 36.58 % of the total effect. These findings suggest a process through which ambiguity tolerance can decrease FLCA and identify the mediating effects of ambiguity tolerance and FLCA in the relationship between learner autonomy and English achievement in Chinese EFL undergraduates. Pedagogical implications of the study are presented and discussed.
The (im)possibility of breaking the cycle of rippling circularities affecting Australian language education programs: a Queensland example
Authors: Díaz Adriana R. , Fillmore Naomi , Cordella Marisa 
Published: June 2023

Abstract
The state of language education in Australia has long been described as paradoxical. Oscillating between periods of increased attention and seeming invisibility, over the last thirty years, the language learning sector has been punctuated by a succession of aspirational declarations and funding injections with little long-term impact on its overall standing. Despite the increasingly multilingual makeup of Australian society, language education at all levels has largely remained stuck amidst monolingualising education policies and alarmist discourses. The latest instance of this paradoxical condition is a fee-reduction incentive for university students to study a language, which, in practice, stands to further weaken the language offerings in many Higher Education institutions. In this paper, we use the imagery of circularities and ripples to explore the challenges facing language education across sectors in Australia. Through data collected in Queensland secondary schools, we discuss how these challenges transcend the traditional delineation of macro-, meso-, and micro-levels of language policy and planning. We argue that challenges go both in circles within the same level (circularity) and flow outwards to other levels (ripples), which include Higher Education. For this reason, siloed approaches to funding and scholarly research contribute to a wicked state of inertia and, ultimately, diminish opportunities to break free from these cycles in the future. We conclude by acknowledging our complicit roles and ethical responsibilities as Higher Education scholars in the perpetuation of these cycles, as but a first step in engaging productively with the possibilities of leveraging these rippling circularities.
Seeing innovation from different prisms: university students’ and instructors’ perspectives on flipping the Spanish language classroom
Authors: García-Allén Ana , Taylor Shelley K. 
Published: June 2023

Abstract
This article focuses on the implementation of a flipped classroom approach in two different levels of Spanish foreign
By foreign language (FL), the authors mean modern language (ML), as strongly suggested by the European Commission.
language university courses for beginner and intermediate learners. The flipped classroom approach delivers course content that prioritizes both digital technology and active learning. Despite its potential advantages in the language classroom, empirical research in this area remains limited. The present study addresses the gap by investigating the effects of the flipped classroom approach on Spanish as a foreign language by comparing student attitudes in flipped and traditional classrooms in beginner and intermediate Spanish courses at a university level. Specifically, this research explores the use of the flipped classroom approach in a second language classroom as a way to present grammar content prior to the in-class lesson and compares the results to those of a traditional, lecture-like delivery of the same grammar content. Drawing on data elicited from students and instructors in these course levels, this study investigates student and instructor perceptions, as well as student autonomy, engagement, and achievement through a qualitative lens.
Tackling the elephant in the language classroom: introducing machine translation literacy in a Swiss language centre
Authors: Cotelli Kureth Sara , Summers Elana 
Published: June 2023

Abstract
University students, especially language learners, have increasingly been using machine translation (MT) systems in the last decade and for all kinds of texts, including homework, assignments and exams. This ubiquity does not translate into visibility as few teachers address the subject in class. Several researchers have shown that MT systems, while technically very easy to access and use, are not always employed in a critical manner. They have therefore suggested that users should develop MT literacy skills. As part of a larger Swiss project on digital literacy in university contexts (DigLit), an action research project at the University of Neuchâtel Language Centre (UniNE LC) seeks to investigate whether delivering a 20-min presentation about machine translation in all L2 classes (French, German, English) at the beginning of the semester was sufficient to foster minimal MT literacy in language learners. All LC students were surveyed at the end of the semester. These survey results were compared with those from a survey of Swiss university students carried out in spring 2021 as part of the DigLit project. These results have allowed us to monitor and enhance the teaching of MT literacy skills in our LC.
Gamification and learning Spanish as a modern language: student perceptions in the university context
Authors: Batlle Rodríguez Jaume , Vicenta González Argüello María 
Published: June 2023

Abstract
Gamification is a methodological strategy that has been applied for several years in the field of modern language learning. It is employed primarily to increase students’ motivation by incorporating game elements into an otherwise didactic context. Research into the use of gamification in language teaching has focused largely on characterizing the specific practices involved and on determining the degree of motivation elicited in students. There has been little examination of students’ perceptions of gamification or their assessment of its effectiveness for learning a modern language. This study analyses learner perception and motivation among a group of sixteen university students of Spanish as a modern foreign language following participation in a gamified learning experience. Analysis of the information gathered from student perception questionnaires and non-participant observation indicates that the students perceive progress in vocabulary learning but not in grammatical knowledge. The students also report a high level of motivation for the proposed learning activities due to the possibility of working collaboratively with their classmates. The article concludes with reflections on the relevance and didactic implications of gamification as a methodological strategy in modern foreign language teaching at higher education level.
IoT-enriched event log generation and quality analytics: a case study
Authors: Grüger Joscha , Malburg Lukas , Bergmann Ralph 
Published: June 2023

Abstract
Modern technologies such as the Internet of Things (IoT) are becoming increasingly important in various fields, including business process management (BPM) research. An important area of research in BPM is process mining, which can be used to analyze event logs e.g., to check the conformance of running processes. However, the data ingested in IoT environments often contain data quality issues (DQIs) due to system complexity and sensor heterogeneity, among other factors. To date, however, there has been little work on IoT event logs, DQIs occurring in them, and how to handle them. In this case study, we generate an IoT event log, perform a structured data quality analysis, and describe how we addressed the problems we encountered in pre-processing.
Ritual Usage of Water in Greek Sanctuaries
Authors: Klingborg Patrik , von Ehrenheim Hedvig , Frejman Axel 
Published: June 2023

SummaryScholars have long highlighted the importance of water for rituals in Greek sanctuaries, but little is known about when and how it was used in practice. Considering the importance attributed to water in rituals at Greek sanctuaries, this article aims to explore water as a purificatory agent for humans and things and as an offering, pure or water mixed with wine, to the gods in the form of libations. Throughout the paper we argue that these activities were located on a spectrum from mundane to religious and can be viewed within a “spatio-temporal” framework where they functioned as visual cues in order to structure activities. To achieve this, we closely and critically examine the empirical material, epigraphic and literary, supported by archaeological and iconographic evidence.
Nemedus Augustus y el culto imperial en áreas rurales de la Península Ibérica
Authors: Cases Mora Noelia 
Published: June 2023

ResumenEl presente artículo considera la inscripción rupestre dedicada a Nemedus Augustus en la cueva de La Griega (Pedraza, Segovia) con el objetivo de aportar algunas reflexiones sobre la interpretación de las divinidades con epíteto Augustus/a, su relación con el culto imperial y su presencia en el ámbito rural hispano. Se consideran otros testimonios epigráficos del uso del epíteto Augustus/Augusta en divinidades indígenas en la Península Ibérica, entendiendo que fue un mecanismo para su incorporación al panteón romano.
The crystal structure of catena-poly[bis(6-phenylpyridine-2-carboxylato-κ2
N,O)-(μ2-4,4′-bipyridne-κ2
N:N)cadmium(II)], C34H24N4O4Cd
Authors: Ping Liu , Li-Hua Wang , Xi-Shi Tai 
Published: June 2023

Abstract

C
34

H
24

N
4

O
4

${\mathrm{C}}_{34}{\mathrm{H}}_{24}{\mathrm{N}}_{4}{\mathrm{O}}_{4}$

Cd, monoclinic, C2/c (no. 15), a = 17.5723(7) Å, b = 11.3574(4) Å, c = 15.8345(7) Å, β =

112.345

(
5
)

°

$112.345(5){}^{\circ}$

, V = 2922.9(2)

Å
3

${\mathrm{\mathring{\text{A}}}}^{3}$

, Z = 4,

R

g
t

${R}_{gt}$

(F) = 0.0265,

w

R

r
e
f

$w{R}_{ref}$

(

F
2

${F}^{2}$

) = 0.0613, T = 200 K.
Synthesis and crystal structure of 2-(2-oxo-2-(o-tolyl)ethyl)-4H-chromen-4-one, C18H14O3
Authors: Liu Yi , Zhao Zhimeng , Zhang Yuming , Liu Feng , Chen Yang , Xiao Tao 
Published: June 2023

Abstract
C18H14O3, triclinic,

P

1
‾

$P\overline{1}$

(no. 2), a = 7.75390(10) Å, b = 8.26060(10) Å, c = 11.6271(2) Å, α =

86.877

(
1
)

∘

$86.877{(1)}^{\circ }$

, β =

78.944

(
1
)

∘

$78.944{(1)}^{\circ }$

, γ =

68.908

(
1
)

∘

$68.908{(1)}^{\circ }$

, V = 681.861(18) Å3, Z = 2,

R

g
t

${R}_{gt}$

(F) = 0.0518,

w

R

r
e
f

$\mathrm{w}{R}_{ref}$

(F
2) = 0.1606, T = 293(2) K.
1H NMR spectroscopy of strongly J-coupled alcohols acquired at 50 mT (2 MHz) using a Carr–Purcell–Meiboom–Gill echo technique
Authors: Ronen Itamar , Webb Andrew G. 
Published: June 2023

Abstract
We have investigated an approach for obtaining 1H NMR spectra of different alcohols on a large-bore (27 cm diameter), B
0 = 0.05 T (f
0 = 2 MHz) portable MRI scanner. We used a Carr–Purcell–Meiboom–Gill (CPMG) sequence to acquire multiecho data from solutions of different alcohols, focusing on ethanol, a molecule of relevance to many applications in the food and beverage industry. Our results show that the Fourier transformed J-spectra at different echo spacings fit well with simulations of the evolution of the echo train signal with excellent signal to noise ratio (SNR) for concentrations of ∼10 % within a few minutes. Spectra were also obtained from intact bottles of whiskey and wine. Finally, we show that different alcohols with similar chemical structures can be differentiated using this approach.
The efficacy of manual therapy on HRV in those with long-standing neck pain: a systematic review
Authors: Harper Brent , Price Parker , Steele Megan 
Published: June 2023

Abstract

Objectives
Long-standing neck pain (LNP) is a clinical condition frequently encountered in the physical therapy clinic. LNP is a complex, multifactorial condition affecting multiple body systems including the autonomic nervous system (ANS). Traditionally, research on the impact of physical therapy on LNP has focused on self-report measures and pain scales. Heart rate variability (HRV) is an objective measure of the ANS, allowing for quantification of effects of treatment. This systematic review is intended to evaluate if manual therapy acutely affects heart rate variability in adults with long-standing neck pain.

Methods
Pubmed, Medline, CINAHL, Google Scholar, Web of Science, and Cochrane library were used to retrieve the randomized controlled trials for this review between the years 2010–2021. Search terms included: chronic neck pain, neck pain, cervical pain, manual therapy, mobilization, manipulation, osteopathy, osteopathic or chiropractic. Heart rate variability, HRV, heart rate variation, effects, outcomes, benefits, impacts or effectiveness.

Results
Of 139 articles located and screened, three full-text articles were selected for full qualitative synthesis, with a combined population of 112 subjects, 91 of which were female, with an average age of 33.7 ± 6.8 years for all subjects. MT techniques in three studies were statistically significant in improving HRV in people with LNP; however, techniques were differed across studies, while one study showed no benefit. The studies were found to be of high quality with PEDro scores ≥6.

Conclusions
Although no clear cause and effect relationship can be established between improvement in HRV with manual therapy, results supported the use of MT for an acute reduction in HRV. No one particular method of MT has proven superior, MT has been found to produce a statistically significant change in HRV. These HRV changes are consistent with decreased sympathetic tone and subjective pain.
Neuroprotective effects of Cubebin and Hinokinin lignan fractions of Piper cubeba fruit in Alzheimer’s disease in vitro model
Authors: Tarbiat Shirin , Unver Demet , Tuncay Salih , Isik Sevim , Yeman Kiyak Bercem , Mohseni Ali Reza 
Published: June 2023

Abstract

Objectives
The current research examines the protective effects of the Piper cubeba ethanolic extract and its isolated lignans; Cubebin and Hinokinin fractions against Alzheimer’s Disease (AD) in vitro model.

Methods
Dried and powdered fruit of P. cubeba were extracted in ethanol and fractionated using silica gel column chromatography. Of the 15 eluted fractions, two fractions indicated presence of targeted Lignans; Hinokinin and Cubebin. They were monitored by thin layered chromatography and their structures were confirmed by LC-HRMS spectrometry and NMR analysis. Antioxidant activity of the crude extract and isolated lignan fractions were analyzed using FRAP, DPPH and ABTS assays. Anti-acetylcholinesterase activity was investigated in vitro and β-amyloid (Aβ) cytotoxicity on SHSY-5Y human neuroblastoma cell lines was studied using MTT assay.

Results
The crude extract showed similar if not significantly stronger antioxidant capacity compared to ascorbic acid in FRAP and DPPH assays. Both lignans exerted weaker yet potent activity. The crude extract yielded the strongest acetylcholinesterase inhibitory potential compared to the lignan fractions however, there was no significant difference (p<0.05) between IC50 values of lignan fractions. Significant neuroprotective effects against 50 μM Aβ at p<0.05 was observed for selected fractions compared to Aβ treated control. The crude extract was highly protective against Aβ at both 5 and 10 μg/mL. Cubebin and Hinokinin-containing fractions significantly improved the viability of the SH-SY5Y cells against Aβ cytotoxicity both only at the concentration of 100 μg/mL.

Conclusions
Results from our studies suggest that these phytoconstituents might be good candidates in prevention and treatment of AD.