bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimization of sustainable corn–cattle integration in Gorontalo Province using goal programming
Authors: Imran Supriyo , Indriani Ria , Hippy Mohammad Zubair 
Published: January 2025

Abstract
Farmers cannot achieve the optimum profits using an integrated system in corn and cattle farming because they are not utilizing their resources in the best way possible. Therefore, finding better ways to use farm waste as animal food and cow manure as corn plant fertilizer is of utter importance. Goal programming enables a combination of production because it can complete several goals simultaneously. To the best of our knowledge, this type of analysis has not been used in previous livestock crop integration studies. Our study aims to (1) determine the optimal production combination in corn–cattle integration and (2) analyze the optimal allocation of resource use in corn–cattle integration. A total of 66 corn–cattle farmers were interviewed for this study. Data were analyzed through a goal programming model using Linear Interactive and Discrete Optimizer. The results indicate that (1) the optimal production combination with profit targets, production costs, and production risks in corn–cattle integration is met, but the achievement value obtained is still below the target, where the best optimal production combination is 14,693 kg of corn, 18 cows, 3,061 kg of corn waste, and 6,087 kg of compost. (2) In the corn–cattle integration system, the best way to use resources is to increase the supply of medicine, land, and labor by one unit. This is true even if those resources are scarce. The sensitivity interval for the optimal use of production resources in the corn–cattle integration system with the target of profit, cost, and production risk can be increased by 1% from the amount of resources used to infinity and can be reduced by 4–16% of the amount of resources used. To be more food secure, independent, wealthy, and able to support ecosystem sustainability in rural areas, farmers should set up an integrated corn–cattle system with the right mix of output and resource allocation.
The Late Bronze Age harbour of Pefkakia: evidence from transport containers suggests site's role
Authors: Lis Bartłomiej , Batziou Anthi 
Published: January 2025

Abstract
Numerous transport stirrup jars have been found at the site of Pefkakia. Most were manufactured in Crete with some from the Greek mainland. There were also at least two Canaanite jars from the Carmel coast. These finds and the first results of petrographic analysis attest to the site's role as a major Aegean harbour.
Immunolocalization of SP22 (Park7) on the human sperm membrane is indicative of live birth
Authors: Klinefelter Gary R , Diamond Michael P , Krawetz Stephen A 
Published: January 2025

With the decline in sperm quality over the recent decades, there is little doubt that the decreased efficiency of spermatogenesis in men reflects their increasing susceptibility to environmental and pharmaceutical exposures that can compromise male fecundity. More than twenty years have passed since we discovered a novel sperm membrane protein (SP22) derived from the Park7 gene that is highly correlated with the fertility of rat sperm exposed to epididymal toxicants. We subsequently discovered that SP22 originates in the testis and is also compromised during exposure to testicular toxicants. Recently, we were given an opportunity to test the hypothesis that human sperm may also have reduced fertility when levels of SP22 are significantly decreased. Using a recombinant antibody to the functional epitope of SP22, we compared sperm from donors who achieved a live birth to donors who were not able to achieve a pregnancy. Sperm SP22 was significantly reduced in a group of donors not able to achieve a pregnancy. A similar reduction in birth was also observed among specific Park7 and SP22 exons when a group of donors unable to achieve a pregnancy was compared to the live birth donors. To our knowledge, this is the first demonstration that SP22 expression can be compromised in men with reduced fertility. This opens the door to incorporating SP22 analyses in future epidemiology studies and developing over-the-counter testing for men with suspected male infertility.Lay summaryEpidemiological studies suggest that sperm quality in men has been declining; however, no biomarkers of fertility were measured in these studies. We discovered a protein (SP22) that was highly correlated with fertility of sperm following toxicant exposures. We sought to evaluate the expression of this protein in men with differing fertility status. Using an antibody to SP22, we compared sperm from donors who achieved a live birth to those who were not able to achieve a pregnancy. This is the first demonstration that SP22 expression, or any sperm membrane protein, is compromised in a random group of men with reduced fertility and provides an opportunity to quantify the expression of SP22 in future epidemiology studies. We also believe that smart phone technology can now be expanded to quantify SP22 in a man’s sperm. This will enable a couple to make more informed decisions about appropriate assisted reproductive procedures.
МАКРО- И МИКРОМОРФОЛОГИЯ ПЛОДОВ НЕКОТОРЫХ ВИДОВ РОДА GERANIUM (GERANIACEAE)
Authors: ТРОШКИНА В.И. 
Published: January 2025

В статье представлены результаты макро- и микроморфологического исследования плодов 41 таксона (40 видов и двух разновидностей) рода Geranium L. из трех подродов и 12 секций. Исследованы форма, размеры, поверхность перикарпия, особенности строения клеток экзокарпия. Для видов G. laetum Ledeb., G. pseudosibiricum J. Mayer, G. asiaticum Serg., G. albiflorum Ledeb., G. malyschevii Troshkina, G. affine Ledeb., G. sergievskajae (Peschkova) Troshkina, G. transbaicalicum Serg., G. turczaninovii (Serg.) Troshkina, G. popovii (Tzvelev) Tzvelev признаки строения плода изучены с помощью СЭМ впервые. Вид G. rotundifoliumпредварительно исключен из секции Batrachioides и, соответственно, подрода Robertium и перенесен в секцию Geranium подрода Geranium . Показано, что морфологию плода и механизм его вскрывания можно использовать для разделения таксонов на уровне рода и подрода; форму мерикарпия, особенности скульптуры поверхности перикарпия - на уровне секции, подсекции и вида.
The article presents the results of macro- and micromorphological study of fruits of 41 taxa (40 species and two varieties) of the genus Geranium L. from three subgenera and 12 sections. The shape, size, surface of the pericarp, and structural features of the exocarp cells were studied. For the species G. laetum Ledeb., G. pseudosibiricum J. Mayer, G. asiaticum Serg., G. albiflorum Ledeb., G. malyschevii Troshkina, G. affine Ledeb., G. sergievskajae (Peschkova) Troshkina, G. transbaicalicum Serg., G. turczaninovii (Serg.) Troshkina, G. popovii (Tzvelev) Tzvelev, the structural features of the fruit were studied using SEM for the first time. The species G. rotundifolium is preliminarily excluded from the section Batrachioides and, accordingly, the subgenus Robertium and transferred to the section Geranium of the subgenus Geranium. It is shown that the morphology of the fruit and the mechanism of its dehiscence can be used to separate taxa at the level of genus and subgenus; the shape of the mericarp, the features of the sculpture of the pericarp surface - at the level of section, subsection and species.
ФУНДАМЕНТАЛЬНЫЙ ТРУД ПО ЛЕСОВЕДЕНИЮ И ГОРНОМУ ЛЕСОВОДСТВУ
Authors: ОНУЧИН А.А. , ПАВЛОВ И.Н. , ПИМЕНОВ А.В. 
Published: January 2025

Представлен обзор книги С. М. Бебия «Леса Абхазии». Монография. Сухум: Академия, 2022. 589 с.
The review is written for the book of Sergei Mikhailovich Bebiya «Forests of Abkhazia». Monograph. Sukhum: Academy, 2022. 589 p. (in Russian with English title, summary and contents).
Between Technological Innovation and Pagan Tradition: The Representation of Lithuania in Contemporary German Travel Literature
Authors: Burov Aleksej , Kotovičius Tomas Vytautas 
Published: January 2025

This article explores Lithuania’s hetero-image as it is created in contemporary German travel literature. The scope of the research primarily covers three German travelogues which detail the authors’ experience during their travels in Lithuania: Drei Baltische Wege (Lucius von, 2011), Wo die Ostsee Westsee heißt (Bünz, 2018) and Gebrauchsanweisung für das Baltikum (Herre, 2014). A further source also contributes to the given analysis: The Strategy for the Presentation of Lithuania abroad 2020–2030, compiled by the Lithuanian government in 2020, and the brief communicative messages conveyed in the document, which revolve around several particulars of Lithuania’s image: economy, culture, history, science and geographic location. These messages mirror Lithuania’s auto image and present the main assessment categories chosen for analyzing the German travelogues. The article concludes that the four most widely covered aspects of economy, culture, history and science, on the one hand, convey an image of a country known for its technological advancement, cultural impact and historical significance. On the other hand, however, they portray an economically underdeveloped and politically unstable country with a generally disgruntled population. Lithuania’s geographic location is tied not to Eastern or Northern Europe, but rather to Central Europe.
An ultra-fast validated green UPLC-MS/MS method for the quantification of osimertinib in human liver microsomes: Screening for ADME parameters and in vitro metabolic stability
Authors: Attwa Mohamed W. , Abdelhameed Ali S. , Kadi Adnan A. 
Published: January 2025

AbstractOsimertinib (Tagrisso, AstraZeneca Pharmaceuticals) is the inaugural third-generation irreversible EGFR-TKI that specifically targets both the EGFR T790M resistant mutation and EGFR-TKI-sensitizing mutations. On September 25, 2024, the Food and Drug Administration authorized osimertinib (OSM) for adult patients with locally advanced, unresectable (stage III) non-small cell lung cancer (NSCLC). The target of this work was to establish a fast, accurate, environmentally friendly, and highly sensitive UPLC-MS/MS methodology for detecting OSM levels in human liver microsomes (HLMs). The separation of OSM and zanubrutinib (ZNB) was accomplished utilizing a C8 column and an isocratic mobile phase. The linearity of the OSM calibration curve spanned from 1 to 3,000 ng mL−1. The AGREE score of 0.76 validates the efficacy of the current approach. The brief in vitro half-life (23.72 min) and moderate intrinsic clearance (34.18 mL min−1 kg−1) of OSM indicate that it resembles drugs with a moderate extraction ratio. The present LC-MS/MS technique is regarded as the primary analytical methodology for quantifying OSM in HLM matrices. The characterization of OSM metabolic stability and in silico ADME features are crucial for progressing the discovery of novel drugs with improved metabolic stability.
Fluid Boundaries and Conflicted Meaning in the Book of Joshua
Authors: Baker Robin 
Published: January 2025

Abstract
This study contends that Joshua in its present form is a layered text in which literary tensions are created and sustained by blurring boundaries of meaning. Joshua’s investigation of boundaries of different kinds is a hermeneutical key to the work. This rhetorical approach mirrors its subject, the tribes’ relationship to the land and its frontiers. A territory intended for subdivision whose border is being crossed requires a focus on frontiers. The vulnerability of boundaries is also implicit in the theological questions the book confronts in its quest to reconcile the divine promise of the land with the fact of exile, namely: What went wrong, and when and why did it go wrong? But the questions it addresses not only concern the past; they also pertain to the future: Who and what will be included within the limits of YHWH’s providence, and where will the boundaries lie? In flexing various types of margins, Joshua probes and illuminates theological conundrums that these questions press upon the reader.
Revisiting Psalm 91 in Light of Rainer Albertz’s Model of Internal Religious Pluralism
Authors: Tucker Jr. W. Dennis 
Published: January 2025

Abstract
Given its similarities to incantation texts found in the larger ancient Near Eastern world, Ps 91 remains sui generis in the Psalter. Despite its seeming uniqueness, the psalm likely enjoyed considerable usage in an array of contexts. To better ascertain this psalm’s usage across different contexts, I employ Rainer Albertz’s model of internal religious pluralism for my analysis. After a review of Albertz’s model, I consider the presence of incantation texts within the domestic sphere in the Levant with particular attention to the Arslan Tash and Ketef Hinnom amulets. I identify incantation elements in Ps 91 and explore the role of Ps 91 in the official cultic religion of ancient Israel. I examine the evidence in the MT Psalter, with particular attention to the psalm’s Sitz im Literatur. In the final portion of the paper, I treat 11QApocryphal Psalmsa (11Q11) and the role of Ps 91 in the Dead Sea collection as an example of the psalm’s use in communal religion.
Transfiguración de Espacios Arquitectónicos a través del arte contemporáneo
Authors: Ursúa Astrain Raúl , Revilla Carrasco Alfonso , Ocaña Mantilla Clara 
Published: January 2025

When conceiving attention as an exclusive selection process, it becomes evident that certain areas of three-dimensional space are underestimated in relation to a visual hierarchy associated with the principle of utility (Rosa et al., 2023), as well as lighting and accessibility. The purpose of this study is to demonstrate that such seemingly peripheral architectural fragments, from the perspective of a Western adult without prior aesthetic education, are chosen by some contemporary artists, emerging as fundamental elements in their artistic discourses. Through a visual analysis of the spatial poetics inherent in these perspectives, which are often overlooked in the perception of architecture, intrinsic connections are established between the works of contemporary artists operating within the expanded field. This study meticulously examines the relevance of the choice of such three-dimensional supports and their impact on the final exhibition proposal.
Generalized Bancroft Algorithm for Locating Earthquakes with P- and S-Wave Arrival Times
Authors: Haney Matthew M. 
Published: January 2025

Abstract
Because of similarities between locating an earthquake with seismic stations and locating a Global Positioning System (GPS) receiver from satellites, the Bancroft algorithm developed for GPS processing can be used to locate earthquakes. Such an approach to earthquake location differs from the conventional method of choosing an initial or trial solution and then iteratively improving the solution until convergence. The Bancroft algorithm has the advantage of being a direct, noniterative solution but with the disadvantage of only being able to accommodate a homogeneous velocity model. An additional limitation of the standard Bancroft algorithm is that it considers arrival times in a medium with a single propagation velocity. This poses no problem for GPS processing because electromagnetic waves travel at the speed of light; however, for seismic waves it means the algorithm can be applied to collections of either P- or S-wave arrival times. Here, I show how the Bancroft algorithm can be generalized to handle both P- and S-wave arrival-time measurements simultaneously. I also show how to accommodate depth-varying P- and S-wave velocity models. I apply the generalized Bancroft algorithm to microearthquakes beneath Tanaga Volcano in Alaska and compare standard locations from the widely used HYPOINVERSE location code to Bancroft locations and to the output of HYPOINVERSE when setting the trial location to the Bancroft location. I find the Bancroft locations outperform the results from the other methods for shallow earthquakes near sea level, where a quantity known as the geometric dilution of precision is large and linearized approaches such as HYPOINVERSE are expected to struggle.
Holter monitoring: Understanding its indications, contraindications, and clinical relevance
Authors: Jana Soumen , Chakraborty Nandita 
Published: January 2025

Holter electrocardiogram monitoring devices play a crucial role in assessing 24-hour heart rate and rhythm, aiding clinicians in evaluating underlying disorders, including arrhythmias. These devices have demonstrated significant clinical importance across various events, both cardiac and non-cardiac, since their inception. They've revolutionized how healthcare settings monitor cardiac rhythm and associated abnormalities, offering numerous applications and clinical benefits. Evidence underscores their efficacy in diagnosing and monitoring cardiac arrhythmias and other cardiovascular conditions, thereby improving patient prognosis and management.It's noteworthy that primary healthcare physicians should remain vigilant as many patients may harbor asymptomatic cardiac arrhythmias. However, there's a scarcity of studies adequately assessing these arrhythmias in non-cardiac populations, emphasizing the need for further investigation. Through this literature review, we aim to explore the indications, contraindications, and clinical significance of utilizing Holter monitoring devices, drawing insights from relevant studies in the field.
Evaluation of the general public\'s health, medication and life style, suffering from diabetes type II in the region of North-central Gujarat, India
Authors: Savaliya Mayur , Sevak Hirava , Purohit Pushti , Shah Hetvi , Patel Archi 
Published: January 2025

: Diabetes mellitus is a complex disease that needs long-term treatment since it causes significant changes in each patient's physical and psychological aspects. Diabetes education is an essential component of therapy that enhances patient results.To evaluate the general public's understanding of and attitude towards diabetes in the North-central Gujarat, Ahmedabad.Door-to-door population survey in the region of North-central Gujarat, Ahmedabad.A 15-point questionnaire was created and the information was gathered and analysed to determine statistically the knowledge, attitude, and practice of the general population and diabetes population as well as to identify important demographic relationships. A comprehensive survey on diabetes reveals a higher prevalence in males (55%) compared to females (45%). Age-related trends demonstrate fluctuating rates in the 40-60 age group, while the 60-80 age group exhibits a significantly higher incidence. Type 2 diabetes, often associated with life style factors, results from impaired insulin secretion or action. Effective diabetes management is crucial not only for immediate health benefits but also for mitigating the risk of long-term complications.
El culto musical a la Virgen María en el Ecuador: el “Stabat Mater Dolorosa” del compositor Manuel María Saquecela
Authors: Freire Soria Carlos 
Published: January 2025

La música es uno de los principales componentes para el culto a la Virgen María en el Ecuador. Algunas obras de compositores nacionales evidencian un sincretismo entre lo vernáculo y lo europeo mientras que, en otras, prima la influencia europea. Se toma como ejemplo de esta última tendencia el Stabat Mater Dolorosa, del compositor gualaceño Manuel María Saquicela (1859 – 1907)PALABRAS CLAVE: Maestro de Capilla; Stabat Mater Dolorosa; Manuel María Saquicela
Identification and Validation of Stable Horse Gram [Macrotyloma uniflorum (Lam.) Verdc.] Genotypes using Multi-trait based Selection Indices in Multi-environment Experiments
Authors: Sulthana J. Sumaiya , Saravanan N.A. , Sivakumar R. , Thirumalraj S. , Vanniarajan C. , Raveendran M. , Geetha S. , Sudhagar R. 
Published: January 2025

Background: Horse gram is an underutilized legume but possesses multi-utilities. The narrower genetic base warrants targeted crop improvement attempts. Induced mutagenesis evolved a few promising mutants for yield whose breeding potency through multiple environment experiments (MEEs) was assessed. Methods: The stability of the high-yielding mutants was assessed through MEEs (six environments in two cropping years) using multiple trait-based selection indices (SIs). The coincidence index was utilized to identify the most common stable genotypes identified by SIs. The effectiveness of the SIs was assessed using the selection differential (SDs). Result: The multi trait-based SIs namely MGIDI, FAI-BLUP and SH index facilitated the selection of superior and stable horse gram mutant genotypes. The results of both preliminary (PT) and confirmatory trials (CT) were analysed using the coincidence index and identified the most common stable mutant genotypes G1, G3, G27 and G22. Based on the SDs for yield-related traits, it is inferred that the SI MGIDI can be relied upon to enhance the genetic gain for yield-associated traits improvement. The SIs, FAI-BLUP and the SH shall be utilized to improve growth-related traits in horse gram.
MEMODERASIKAN PEMBELAJARAN AGAMA ISLAM DI PERGURUAN TINGGI SEBAGAI LANGKAH ANTISIPATIF MEMBENDUNG PENYEBARAN PAHAM EKSTREM
Authors: Khazin A. Mufti , Jailani Imam Amrusi 
Published: January 2025

Salah satu topik perbincangan yang sedang aktual di berbagai media adalah masalah moderasi beragama. Moderasi beragama harus menyentuh seluruh aspek kehidupan, termasuk di dalamnya kehidupan akademik. Saluran moderasi beragama di perguruan tinggi dapat melalu pembelajaran. Pembelajaran Agama Islam merupakan suatu rangkaian materi mata kuliah yang eksistensinya sudah diakui di pentas akademik dan sudah terintegrasi dengan beberapa mata kuliah yang diajarkan di Perguruan Tinggi. Namun persoalannya, sudah sejauh mana moderasi beragama mampu mewarnai pembelajaran agama di perguruan tinggi. Seberapa kuat civitas akademik mampu membentengi diri dari dari gempuran kelompok-kelompok ekstrem yang akhir-akhir ini sudah banyak merambah ke dunia kampus. Kemudian, langkah antisipatif apa saja yang harus dilakukan untuk membentengi para mahasiswa dari incaran sebagai “penganten” ekstrem, serta solusi pemecahannya bagi mereka yang sudah terpapar paham ekstrem. Moderasi pembelajaran agama di perguruan tinggi menjadi topik bahasan dalam tulisan ini, dan akan diuraikan secara sistematis.

One of the current topics of discussion in various media is the issue of religiousmoderation. Religious moderation must touch all aspects of life, including academic life. The channel of religious moderation in universities can be through learning. Islamic Religious Learning is a series of subject matter whose existence has been recognized on the academic stage and has been integrated with several courses taught in universities. But the problem is how far has religious moderation been able to color religious learning in universities. How strong the academic community is able to fortify themselves from the onslaught of extreme groups that have recently penetrated the campus world. Then, what anticipatory steps must be taken to fortify students from being targeted as extreme "brides", as well as solutions for those who have been exposed to extreme ideas. Moderation of religious learning in higher education is the topic of discussion in this paper, and will be described systematically.