bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pulse respiration quotient as a measure sensitive to changes in dynamic behavior of cardiorespiratory coupling such as body posture and breathing regime
Authors: Matić Zoran , Kalauzi Aleksandar , Moser Maximilian , Platiša Mirjana M. , Lazarević Mihailo , Bojić Tijana 
Published: December 2022

Objective: In this research we explored the (homeo)dynamic character of cardiorespiratory coupling (CRC) under the influence of different body posture and breathing regimes. Our tool for it was the pulse respiration quotient (PRQ), representing the number of heartbeat intervals per breathing cycle. We obtained non-integer PRQ values using our advanced Matlab® algorithm and applied it on the signals of 20 healthy subjects in four conditions: supine position with spontaneous breathing (Supin), standing with spontaneous breathing (Stand), supine position with slow (0.1 Hz) breathing (Supin01) and standing with slow (0.1 Hz) breathing (Stand01).Main results: Linear features of CRC (in PRQ signals) were dynamically very sensitive to posture and breathing rhythm perturbations. There are obvious increases in PRQ mean level and variability under the separated and joined influence of orthostasis and slow (0.1 Hz) breathing. This increase was most pronounced in Stand01 as the state of joint influences. Importantly, PRQ dynamic modification showed greater sensitivity to body posture and breathing regime changes than mean value and standard deviation of heart rhythm and breathing rhythm. In addition, as a consequence of prolonged supine position, we noticed the tendency to integer quantization of PRQ (especially after 14 min), in which the most common quantization number was 4:1 (demonstrated in other research reports as well). In orthostasis and slow breathing, quantization can also be observed, but shifted to other values. We postulate that these results manifest resonance effects induced by coupling patterns from sympathetic and parasympathetic adjustments (with the second as dominant factor).Significance: Our research confirms that cardiorespiratory coupling adaptability could be profoundly explored by precisely calculated PRQ parameter since cardiorespiratory regulation in healthy subjects is characterized by a high level of autonomic adaptability (responsiveness) to posture and breathing regime, although comparisons with pathological states has yet to be performed. We found Stand01 to be the most provoking state for the dynamic modification of PRQ (cardiorespiratory inducement). As such, Stand01 has the potential of using for PRQ tuning by conditioning the cardiorespiratory autonomic neural networks, e.g., in the cases where PRQ is disturbed by environmental (i.e., microgravity) or pathologic conditions.
Bright, but allergic and neurotic? A critical investigation of the “overexcitable genius” hypothesis
Authors: Fries Jonathan , Baudson Tanja Gabriele , Kovacs Kristof , Pietschnig Jakob 
Published: December 2022

IntroductionHigher intelligence has been associated with improved health and longevity. However, recent findings have claimed that exceptional intelligence may come at a cost. Individuals at the upmost end of the intelligence distribution are reported to be disproportionately afflicted by a set of stress-related physical and mental health conditions: so-called overexcitabilities. Few accounts have investigated this issue and no studies are available for non-US samples yet. Here, we aimed to replicate and extend previous work by examining hitherto unaddressed overexcitabilities in a European high-IQ sample.MethodsWe carried out a preregistered survey among members of MENSA, the world’s largest high-IQ society. In total, 615 (307 male) members from Austria, Germany, Hungary, Switzerland, and the United Kingdom participated.Results and DiscussionCompared to the general population, our sample exhibited considerably elevated prevalences in autism spectrum disorders (risk ratio/RR = 2.25), chronic fatigue syndrome (RR = 5.69), depression (RR = 4.38), generalized anxiety (RR = 3.82), and irritable bowel syndrome (RR = 3.76). Contrary to previous accounts, neither asthma, allergies, nor autoimmune diseases were elevated. We show that this subsample of intellectually gifted persons faces specific health challenges compared to the general population. The reasons for this remain speculative, as we find little evidence for previously proposed immunological explanations. However, it is possible that the effects are caused by sample selectiveness (i.e., membership in a high-IQ society) rather than high IQ itself.
Acupuncture and related therapies for the anxiety and depression in irritable bowel syndrome with diarrhea (IBS-D): A network meta-analysis of randomized controlled trials
Authors: Wang Xuesong , Shi Xuliang , Lv Jing , Zhang Juncha , Huo Yongli , Zuo Guang , Lu Guangtong , Liu Cunzhi , She Yanfen 
Published: December 2022

ObjectiveA growing number of clinical studies have suggested the value of acupuncture-related therapies for patients with irritable bowel syndrome with diarrhea (IBS-D), and the patient’s mental state plays an important role, but there are many types of acupuncture-related therapies involved. This study aimed to evaluate the mental status, efficacy and safety of the different acupuncture-related therapies for IBS-D patients.MethodsWe searched seven databases to collect randomized controlled trials of acupuncture-related therapies for IBS-D. After independent literature screening and data extraction, the quality of the final included literature was evaluated. Hamilton anxiety rating scale (HAMA), hamilton depression rating scale (HAMD), self-rating anxiety scale (SAS), and self-rating depression scale (SDS) was used as the primary outcome indicator. And the network meta-analysis (NMA) was performed by using Revman 5.4, Stata 15.0 and WinBUGS 1.4.3 software, and the surface under the cumulative ranking curve was conducted to rank the included interventions.ResultsWe analyzed 24 eligible studies with 1,885 patients, involving eight types of acupuncture and related therapies along with comprehensive therapies. The NMA result shows that: for SAS scores, combined therapies were more efficacious than anti-diarrheal or antispasmodic (western medicine, WM) (SMD: −8.92; 95% CI: −15.30, −2.47); for SDS scores, combined therapies were more efficacious than WM (SMD: −8.45; 95% CI: −15.50, −1.41). For HAMA scores, moxibustion (MOX) was more efficacious than placebo (SMD: −8.66; 95% CI: −16.64, −0.38). For HAMD scores, MOX was more efficacious than all other included interventions. For response rate, MOX was more efficacious than the following interventions: acupuncture (ACU) (SMD:0.29; 95% CI:0.08,0.93), Chinese herb medicine (CH) (SMD:0.09; 95% CI:0.02,0.36), combined therapies (SMD:0.23; 95% CI:0.06, 0.85), electroacupuncture (EA) (SMD:0.06; 95% CI:0.01,0.33), warm acupuncture (WA) (SMD:22.16; 95% CI:3.53,148.10), WM (SMD:15.59; 95% CI:4.68,61.21), and placebo (SMD:9.80; 95% CI:2.90,45.51). Combined therapies were more efficacious than the following interventions: CH (SMD:0.39; 95% CI:0.19,0.80), WA (SMD:4.96; 95% CI:1.30,21.62), and WM (SMD:3.62; 95% CI:2.35,5.66). The comprehensive ranking results show that MOX, ACU, combined therapies, and EA had high SUCRA rankings involving different outcome indicators.ConclusionMOX, ACU, combined therapies, and EA better alleviate anxiety and depression among IBS-D patients, and with a higher safety level, may be the optimal therapies. In addition, combining acupuncture-related treatments and other therapies also delivers a higher global benefit level.Systematic review registration[https://www.crd.york.ac.uk/], identifier [CRD42022364560].
Well-being and well-becoming through the life-course in public health economics research and policy: A new infographic
Authors: Edwards Rhiannon Tudor 
Published: December 2022

BackgroundThe term “well-becoming” is not new, but is not routinely used in our everyday language or in research in public health economics. It has been applied in early years research. Well-becoming can be thought of as our multitude of life-journeys toward meaning and purposefulness.ObjectiveTo develop a new infographic in the spirit of the Dahlgren and Whitehead rainbow infographic of social determinants of health. The purpose being to redefine well-being as a process of growth through life, articulated as well-becoming.MethodsA rapid review of life-course stage appropriate models of well-being was undertaken with stages of the life-course as defined as: preconception and birth; early years; adolescence; working, parenting and caring; older age, and death. Infographics in this area were identified and the information above was used to design a new infographic with the concept of well-being and well-becoming at its center.ResultsA new infographic reflecting an underlying concept of “the wheel of life” is presented. It shows movement through the life-course at its center, with concentric rings summarizing personal, local, and national and global factors that have an impact on well-being and well-becoming of individuals through the life-course. Of note, is the inclusion of death, which is a topic often avoided. Prepared during 2021–22, the infographic reflects the role of pandemic and war within the national and global ring of influential factors. I reflect on three ways in which health economists are currently using a life-course approach and the concept of well-becoming in the economic evaluation of individual programs and at a population level of government policy.ConclusionMoving from solely focusing on a concept of well-being to a concept of well-being and well-becoming acknowledges the influence that socioeconomic and other conditions in a particular life-course stage have on subsequent life-course stages, and the cost-effectiveness of intervening across the life-course.
The association between problematic smartphone use and the severity of temporomandibular disorders: A cross-sectional study
Authors: Pei Ya-Peng , Li Han-Chao , Zhong Jia-Wei , Gao Xin-Lin , Xiao Chu-Qiao , Yue Yuan , Xiong Xin 
Published: December 2022

ObjectiveTo evaluate the prevalence of different types of temporomandibular disorders (TMD) symptoms in young adults and determine their associations with problematic smartphone use (PSU).MethodsThe data of the study were collected from local university students through an online questionnaire survey. Demographic information, Fonseca Anamnestic Index (FAI), Smartphone Addiction Scale-Short Version (SAS-SV), and Patient Health Questionnaire-4 (PHQ-4) responses were gathered electronically and analyzed using multiple logistic regression analysis.ResultsThere were 163 male and 307 female respondents were participated in this study. The prevalence of PSU and TMD were 83.6% and 66.4%, respectively. There was a moderate statistical correlation between PSU and TMD among young adults (r = 0.31, p &lt; 0.01). The logistic regression model revealed that the risk of TMD was 1.77 times higher in people with PSU than in those without PSU (OR = 1.77; 95% CI 1.04–3.06). PSU is a risk factor for pain-related TMD (OR = 1.81; 95% CI 1.08–3.04) but not intra-articular TMD.ConclusionSubjects showed high prevalence of both TMD and PSU. People with PSU experienced more severe and frequent pain-related rather than intra-articular TMD symptoms than those without PSU. By reducing the problematic smartphone use, the risk factor of TMD might be avoided.
Patient safety and staff psychological safety: A mixed methods study on aspects of teamwork in the operating room
Authors: Arad Dana , Finkelstein Adi , Rozenblum Ronen , Magnezi Racheli 
Published: December 2022

ObjectivesTo predict the amount of teamwork that takes place throughout a surgery, based on performing a preoperative safety standards (surgical safety checklist and surgical count) and to explore factors affecting patient safety and staff psychological safety during a surgery, based on interprofessional teamwork.MethodsThis mixed methods study included quantitative and qualitative analyses. Quantitative data included 2,184 direct observations of surgical cases with regard to the performance of safety standards during surgeries in 29 hospitals, analyzed using multivariate binary logistic regressions. Qualitative data were obtained from an analysis of 25 semi-structured interviews with operating room (OR) clinicians and risk managers, using an inductive thematic analysis approach.ResultsAnalysis of the OR observations revealed that a lack of teamwork in the preoperative “sign-in” phase doubled the chances of there being a lack of teamwork during surgery [odds ratio = 1.972, 95% confidence interval (CI) 1.741, 2.233, p &lt; 0.001] and during the “time-out” phase (odds ratio = 2.142, 95% CI 1.879, 2.441, p &lt; 0.001). Consistent presence of staff during surgery significantly increased teamwork, by 21% for physicians and 24% for nurses (p &lt; 0.05), but staff turnover significantly decreased teamwork, by 73% for physicians (p &lt; 0.05). Interview data indicated that patient safety and staff psychological safety are related to a perception of a collaborative team role among OR staff, with mutual commitment and effective interprofessional communication.ConclusionsHealthcare organizations should consider the key finding of this study when trying to identify factors that affect teamwork during a surgery. Effective preoperative teamwork positively affects intraoperative teamwork, as does the presence of more clinicians participating in a surgery, with no turnover. Other factors include working in a fixed, designated team, led by a surgeon, which functions with effective interprofessional communication that promotes patient safety and staff psychological safety.
Consistency between 3 days' dietary records and 24-h urine in estimating salt intake in children and adolescents
Authors: Dong Jie , Yu Xiaoran , Li Xun , Xiang Shiting , Qin Yongquan , Zhu Shaolun , Zheng Jie , Yan Yinkun 
Published: December 2022

PurposeThis study aimed to evaluate the salt intake in boarding school students and the consistency between salt intake measurements based on 24-h urine and weighed dietary records over 3 consecutive days in this population.MethodsThis was a school-based cross-sectional study. Overweight (including obesity) or hypertensive students aged 6–14 years and their normal counterparts were recruited for this study at three boarding schools in China. Three consecutive 24-h urine samples were collected from all participants. During the collection period of 24-h urine, the weighed diet records were collected in children who had all three meals at the school canteens on weekdays. Incomplete 24-h urine or dietary records were excluded from the analysis.ResultsThe median salt excretion was 6,218 [4,636, 8,290] mg by 24-h urine and 120 (82.2%) consumed excess salt among the participants. The median salt intake was 8,132 [6,348, 9,370] mg by dietary records and 112 (97.4%) participants consumed excess salt than recommended in participants who have all three meals in the school canteens. In children with complete dietary records and 24-h urine, the level of salt intake estimated by 24-h urine accounted for 79.6% of the dietary records.ConclusionOur study showed that boarding school students consumed excessive salt from school canteens. Thus, policies or strategies targeting school canteens are urgently needed. Weighed dietary records are recommended if feasible.
Revisiting cloud overlap with a merged dataset of liquid and ice cloud extinction from CloudSat and CALIPSO
Authors: Oreopoulos Lazaros , Cho Nayeong , Lee Dongmin 
Published: December 2022

We update the parameterization capturing the variation of parameters that describe how cloud occurrence (layer cloud fraction) and layer cloud optical depth (COD) distributions overlap vertically. Our updated analysis is motivated by the availability of a new dataset constructed by combining two products describing the two-dimensional extinction properties of liquid and ice phase clouds (and their mixtures) according to active cloud observations by the CloudSat and CALIPSO satellites. As before, cloud occurrence overlap is modeled with the decorrelation length of an inverse exponential function describing the decay with separation distance of the relative likelihood that two cloudy layers are overlapped maximally versus randomly. Similarly, cloud optical depth distribution vertical overlap is described again with a decorrelation length that describes the assumed inverse exponential decay with separation distance of the rank correlation between cloud optical depth distribution members in two cloudy layers. We derive the climatological zonal variability of these two decorrelation lengths using 4 years of observations for scenes of ∼100 km scale length, a typical grid size of numerical models used for climate simulations. As previously, we find a strong latitudinal dependence reflecting systematic differences in dominant cloud types with latitude, but substantially different magnitudes of decorrelation length compared to the previous work. The previously used parameterization form is therefore updated with new parameters to describe the latitudinal dependence of decorrelation lengths and its seasonal shift. Similar zonal patterns of decorrelation length are found when the analysis is broken down by different cloud classes. When the revised parameterization is implemented in a cloud subcolumn generator, simulated column cloud properties compare to observations quite well, and so do their associated cloud radiative effects, but improvements over the earlier version of the parameterization are marginal.
The surgical strategy for multilevel massive ossification of the posterior longitudinal ligaments
Authors: Li Ying-Ching , Liu Zhuo-Hao , Li Ying-Sheng , Yeap Mun-Chun , Liu Yu-Tse , Huang Yin-Cheng , Chen Ching-Chang , Tu Po-Hsun 
Published: December 2022

PurposeCreating enough decompression, favorable outcome, less complication, and maintain adequate lordosis and stability in the patients with cervical myelopathy due to multilevel massive ossification of the posterior longitudinal ligament (OPLL) still poses a challenge for surgeons. The aim of our study is to retrospectively evaluate our patients and try to seek a better surgical strategy.MethodsBetween 2015 and 2019, 55 consecutive patients with multilevel massive OPLL underwent surgical treatment. Among these, 40 patients were treated with cervical laminectomy and then anterior decompression, fusion, and fixation (ADF), which was defined as group 1, and 15 patients were treated with cervical laminectomy and fixation simultaneously, which was defined as group 2. The patient's radiographic characteristics and postoperative outcomes were evaluated.ResultsBetter postoperative cervical sagittal lordosis and less long-term axial pain was achieved in group 1 (p &lt; 0.001), though the functional outcome had no significant difference. In the multivariable analysis, anterior fixation accounts for independent factors for better cervical sagittal alignment (p &lt; 0.001). No complications directly associated with cervical laminectomy were observed.ConclusionIn patients with cervical multilevel massive OPLL, laminectomy at compression level and then ADF depended on the severity and range of compression, but corpectomy of not more than two vertebral bodies is suggested, except K-line (+) and long-segment massive OPLL majorly involving the C2 and posterior laminectomy above and below the OPLL-affected levels with posterior fixation simultaneously.
A Wideband Eight-Element Antenna with High Isolation for 5G New-Radio Applications
Authors: Cai Jing , Zhang Juhui , Xi Shuqi , Huang Jianlin , Liu Gui 
Published: December 2022

A wideband multiple-input multiple-output (MIMO) antenna with high isolation for fifth-generation (5G) new-radio (NR) smartphone employment operating at a range from 3.3–5 GHz is presented in the paper. The wideband antenna is comprised of eight identical radiation units and applies defected ground structure (DGS) to offer higher isolation between antenna units. Each of the antenna elements is formed of a C-shaped microstrip line, two triangle-shaped strips and a rectangular strip. The measurement results present that the transmission coefficients of the presented antenna are smaller than −18 dB in the required wideband, and the envelope correlation coefficient (ECC) values are better than 0.005. The realized gain and efficiency of the designed antenna are about 3.5 dBi and higher than 75%, respectively. The volume of this total antenna is 150 × 75 × 7 mm3, and the measurement of each antenna unit is merely 6.8 mm × 7 mm × 0.8 mm (0.077 λ×0.08 λ×0.009 λ, λ is the wavelength of 3.4 GHz). The presented MIMO antenna is suitable for 5G new-radio (NR) smartphone applications.
Effects of Dietary Blend of Algae Extract Supplementation on Growth, Biochemical, Haemato-Immunological Response, and Immune Gene Expression in Labeo rohita with Aeromonas hydrophila Post-Challenges
Authors: Sattanathan Govindharajan , Liu Wen-Chao , Padmapriya Swaminathan , Pushparaj Karthika , Sureshkumar Shanmugam , Lee Jang-Won , Balasubramanian Balamuralikrishnan , Kim In Ho 
Published: December 2022

In this study, the effects of a mixed algal blend (Chlorella vulgaris, Euglena viridis, and Spirulina platensis) at different levels were evaluated on growth, hematological immune responses, and expression of immune genes in Labeo rohita against post-challenges of Aeromonas hydrophila. Fish samples were fed a diet containing different levels of mixed blend algal (0, 0.01, 0.02, 0.04 and 0.08% of basal diet). At the end of the feeding period, the fish were challenged with A. hydrophila and fish mortality was recorded over a 14-days period. To evaluate the serum biochemical (albumin, globulin), hematological parameters (Hb, RBC and WBC) and immune parameters (neutrophil activity, lysozyme activity, myeloperoxidase activity, antiprotease activity, ceruloplasmin activity, and bactericidal activity), as well as the expression of immune genes (NKEF-B, Lysozyme C and G, TNF α, TLR22, β2M, and β-actin), fish were sampled on Day 7, 14, 21 and 28. Fish were challenged with virulent A. hydrophila 30 days post-feeding and mortalities were recorded over 30 days post-infection. Results demonstrate that fish fed with a mixed algal blend showed that total body weight gain, specific growth rate, total serum protein, globulin, total hemoglobin content, white blood cells, neutrophil, lysozyme, bactericidal, myeloperoxidase, and antiprotease activity in dietary algae blended application was higher than in the control (p < 0.05). According to the results, relative expression of target genes showed significant increases of 0.02 to 0.04% in the treatment group compared to the control group (p < 0.05). At the end of the 30-day exposure to A. hydrophila, the fish that received the mixed algal blend had a significantly higher rate of survival than the control group, with the highest survival rate recorded in the 0.02% mixed algal blend (p < 0.05). According to the effective results of the mixed algal blend on stimulating the immune system and increasing fish resistance to A. hydrophila, it is recommended to use 0.02 to 0.04% of this mixed algal blend in rohu, L. rohita diets.