bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Coal Seam Presence In-Between Comparatively Denser Layers Over High Wall Slope Stability-A Case Study of Kistaram Project, Singareni Collieries Company Limited (SCCL)
Authors: Surya Jaya Chandra V. , Sandeep Panchal , Sirdesai Nikhil Ninad 
Published: March 2023

Abstract
The lithology in the region of Godavari Valley Coal Fields of Southern India is mainly composed of sandstones of different types, clay combined with shale, coal seams and some other soft rocks. Due to variations in the strength properties of different layers, the lower strength material easily tends to slip along the bedding plane or may creep up due to the compression offered by the overlying layers and affect the stability of slope in open-pit mines. In this study, influence of coal seams present inbetween sandstones on the overall stability of a high wall benches of Kistaram opencast mine of Singareni Collieries Company Limited (SCCL) is studied using FLAC3D tool. The stability analysis of highwall benches in different phases of bench formation (exposure of coal seams namely A, LB1, LB2) is carried out by interpreting the stress, strain, displacement values at selected plane on each bench. It was deduced that presence of weak layers in between the comparatively denser layers have a major impact over the stability of the slope and local failures were observed along the slope after exposure of each coal.
Early Miocene (Burdigalian) Dinoflagellate Cysts from the Kerala Basin, Southwest India: Indicators of Marine Ingression at the Onset of the Mid-Miocene Climate Optimum (MMCO)
Authors: Singh Yogesh Pal , Verma Poonam , Singh Abha , Bali Rameshwar 
Published: March 2023

Abstract
In the present study, the assemblages of organic walled dinoflagellate cyst (dinocysts) and calcareous nannofossils from Quilon Formation, Kerala Basin, south-western India are analyzed for age interpretation and reconstruction of the depositional environment. The integrated biostratigraphy based on dinocysts and calcareous nannofossils from the same sediment samples indicates that the studied succession was deposited during the early Miocene (middle Burdigalian, ~19-17.5 Ma) time. The dinocyst assemblages contain abundant taxa (Cleistosphaeridium, Polysphaeridium, Lingulodinium, Homotryblium and Spiniferites) that range from shallow inner to outer neritic marine zone. The abundance of autotrophic, thermophilic taxa suggests relatively high surface water temperatures and high nutrient availability. The dinocyst assemblage in the lower part of the studied succession is dominated by Cleistosphaeridium spp., Polysphaeridium spp., Spiniferites spp., Homotryblium spp. and Lingulodinium spp. An increase in the relative abundances of outer neritic dinocyst taxa such as Spiniferites, Achomosphaera and Hystrichokolpoma in the upper part of the succession suggests a change towards more open marine conditions created during marine ingression. The interpreted marine ingression along the south-western Indian coast probably corresponds to the initial small pulses of transgression at the onset of the long-term global sea-level maximum related to the Mid-Miocene Climatic Optimum (MMCO).
Study of Freeze-thaw Induced Damage Characteristic for Himalayan Schist
Authors: Verma A.K. , Sardana Sahil , Jaiswal Amit 
Published: March 2023

Abstract
The freeze-thaw (F-T) induced deterioration in rocks affects their durability, leading to various landslides, rockslides, and avalanches. The study focuses on estimating loss in rock strength using mineralogical properties under the influence of multiple F-T cycles. The rock samples were collected from F-T affected north Indian Himalayan region. The rock specimens were subjected to multiple F-T conditioning (0th, 10th, 20th and 30th F-T cycles). The mineralogical properties (such as mineralogical indices and textural indices) and mechanical properties (such as uniaxial compressive strength; UCS and Brazilian tensile strength; BTS) were calculated before and after F-T conditioning. A correlation was developed among the various strength properties and mineralogical properties. The result shows a strong relationship between the UCS and BTS with mean grain size. Further, results were used to develop a mathematical model, based on mineralogical parameter and decay function, to predict the rock strength under the influence of multiple F-T cycles.
GIS-based Spatial Variability and Water Quality Index (WQI) Modeling of Trace Elements in Groundwater of Jamshedpur, Eastern India
Authors: Mahato Jaydev Kumar , Saw Shivam , Kant Nishi , Patel Rohit , Yadav Brahmdeo 
Published: March 2023

Abstract
The present study investigated the spatial variability and water quality index (WQI) modeling of groundwater for drinking purposes. Thus, the sample from 30 locations in Jamshedpur city was collected to explore the hydrochemical characteristics. The range of values of trace elements was well complied with the Bureau of Indian Standards (BIS) except Co (0.1 to 13.87 µg/L), Cu (0.12 to 64.62 µg/L), Mn (20 to 1461 µg/L), and Sr (30 to 544 µg/L).The water table of this region showed tremendous variation (0.44 to 4.90 mbgl) as monitored by a sensor-based water level recorder. The WQI model revealed that only 4% of the water in this region is under the excellent categories, followed by good (86%) and poor (10%). Human health risk assessment of trace elements in contaminated groundwater was also performed according to the United States Environmental Protection Agency (USEPA). The estimated hazard index (HI) value (4.85E-02 to 1.61E+00) indicated the non-carcinogenic risk. The study provides immense help for public health decision-makers to prevent the communities health risks.
The role of the body in electronic sport: a scoping review
Authors: Riatti Paolo , Thiel Ansgar 
Published: March 2023

AbstractThe popularity of competitive computer and videogaming, also known as electronic sport (esport), has been rising rapidly during the past decades. Because of many parallels with traditional sports, like competitiveness, skill requirements, degree of professionalization, or the way it is portrayed in the media, esport has been adopted as part of the sport canon in many countries. Still, critics argue that playing computer games lacks the physicality commonly seen in traditional sports. A significant part of the competition is mediated through digital platforms and the spotlight shifts from the players’ appearance and actions to their digital avatars. This paper takes on this issue by exploring existing evidence about the role of the body in esport via a scoping review approach. According to the findings of 47 studies, the body’s role in esport is akin to that in traditional sport, including specific motoric requirements or biometric responses. Beyond that, the body can be seen as a link between the digital and physical worlds. Players embody digital avatars in the form of esport-specific movements, transfer of norms and ideals, and identification with the in-game characters. Future research can use this review as a basis for scientific approaches to individual phenomena regarding corporeality in esport and inter-corporeality.
Evaluation of physicochemical properties in agricultural soils on the flat and piedmont areas of Valle del Cauca, Colombia with emphasis on degradation
Authors: Marín-Pimentel Gilberto-Eduardo , Rueda-Saa Germán , Menjivar-Flores Juan Carlos 
Published: March 2023

AbstractA study for the physicochemical properties was carried out in agricultural soils (n = 489) on the flat and piedmont areas of Valle del Cauca. The degradation level of different soils (n = 489) was studied by determining and analyzing their properties. Variability and distribution analysis, central tendency, dispersion and multivariate analysis were included. The results showed that the saturated hydraulic conductivity (Ks) and electrical conductivity (EC) were highly variable. The other properties were moderately variable, depending on the coefficient of variation (10% < CV < 100%). The principal component analysis indicated that the first component was related to compaction processes in the soil (34%), the second included nutrients available to plants (24%), and the third (13%) was the movement of cations. The more susceptible to degradation properties included apparent density (Da) and porosity (η), which had normal distribution (P > 0.150). 19% of the evaluated sites had possible soil compaction, with high Da values (> 1.6 g cm−3) and low η (< 40%). The degradation from salinity was minimal, and only 2.2% of the samples had EC values greater than 2 dS m−1. 50% of the soils had organic matter levels (MO) greater than 2%. 85.5% had cation exchange capacity values (CEC) that exceeded 15 cmol (+) Kg−1, and 42.12% were in the pH range from 5.5 to 7.0, optimal conditions for crops. The results showed that soil compaction occurred in some agricultural crops; however, most than 80% of the soils studied had excellent physicochemical properties (MO, CEC, pH).
Radiotherapy combined with anti-CEACAM1 immunotherapy to induce survival advantage in glioma
Authors: Li Jinhu , Chen Yi , Fan Yimin , Wang Hongqin , Mu Wei , Liu Xiaodong 
Published: March 2023

Abstract
Background
We aimed to observe the effect of radiotherapy on the expression of immune checkpoint molecule CEACAM1 in patients with glioma and the therapeutical effect of radiotherapy combined with blockade of CEACAM1 in mice with intracranial gliomas.

Methods
The expression of CEACAM1 on T-lymphocytes in the peripheral blood of patients with glioma was detected before and after radiotherapy; GL261 murine glioma cells (stably transfected with the luciferase gene) were implanted in the right caudate nucleus of C57BL/6 mice, and tumour growth was observed using the small animal in vivo imaging system. Mice were divided into 4 groups: (1) the isotype control; (2) the radiotherapy; (3) the anti-CEACAM1 treatment; and (4) the combination therapy. The survival of mice after treatment was recorded; the expression of CEACAM1 on murine glioma cells was detected by immunohistochemistry before and after radiotherapy; flow cytometry was adopted to detect CD8+ T-cells (Treg) (CD4+FoxP3+CD25+) among mouse brain-infiltrating T-cells; serum levels of IFN-γ and IL-10 were detected by ELISA; proliferation and apoptosis were observed by immunohistochemistry; Retrospective RNA-seq data analysis was conducted in a cohort of 325 patients with glioma in the Chinese Glioma Genome Atlas (CGGA) database and 702 patients in The Cancer Genome Atlas (TCGA) database.

Results
The expression of CEACAM1 on CD4+ and CD8+ T-cells in the peripheral blood of patients with glioma was significantly higher 1 week after radiotherapy than before radiotherapy and was further increased 1 month after radiotherapy. Combined therapy notably inhibited the growth of intracranial tumours in mice and prolonged their survival time, with some mice being capable of surviving long-term (> 90 d). Immunohistochemistry revealed that the expression of CEACAM1 in murine glioma tissues after radiotherapy was elevated in a time-dependent manner. Flow cytometry analysis showed an increase in mouse brain-infiltrating CD8+ T-lymphocytes, a decrease in Treg cells, and an increase in CD8+ T/Treg cells after treatment. ELISA demonstrated the elevated levels of IFN and decreased levels of IL-10 in the serum of mice in the combination therapy group.

Conclusions
Radiotherapy combined with CEACAM1 inhibitors resulted in strong and durable anti-tumour immune responses against murine glioma and long-term survival of some mice. Hence, this study is expected to offer new effective immunotherapy strategies against glioma.
The role of stakeholder involvement in EU research and innovation policy: a case study of Technology Platform Organics
Authors: Gambelli Danilo , Vairo Daniela , Cuoco Eduardo , Zanoli Raffaele 
Published: March 2023

Abstract
This paper analyses the importance that participatory approaches may play in shaping the innovation policy in the context of the EU research framework programme. The paper reports case study research on the role of “TP Organics”, a European Technology Platform (ETP) that supports research and innovation in organic farming in the EU. The case study is based on data concerning the relevance of resources pertaining to organic farming in the EU’s most recent framework programmes for research and development (FP7 and Horizon 2020). We use process tracing to analyse the causal effects of the participatory approach used by TP Organics in defining policies and promoting funding for the organic sector. Data concerning textual content analysis on research calls and budget disaggregation for EU research funding are used to test the hypothesis that the engagement of stakeholders provides substantial effects in terms of the number of research projects explicitly oriented to organic farming and the amount of research funding made available. Results refer to the outcomes of a structured testing sequence for the key hypotheses supporting the causal model. They show that the impact of TP Organics relies on its successful multi-stakeholder participatory processes, which have improved the relevance of research themes related to organic farming and have ultimately yielded an increase in financed research projects and financial contributions to research on organic farming in the EU. Conclusions provide some theoretical generalisations on the importance of stakeholder engagement in successfully lobbying for research policy.
Efficacy and safety of needle-free jet injector-assisted intralesional treatments in dermatology—a systematic review
Authors: Bekkers Vazula Zulfra , Bik Liora , van Huijstee Johanna Catharina , Wolkerstorfer Albert , Prens Errol Prospero , van Doorn Martijn Bastiaan Adriaan 
Published: March 2023

AbstractNeedle-free jet injectors are used for the intralesional treatment of various dermatological indications. However, a systematic review that evaluates the efficacy and safety of these treatments has not been published. The objectives of this study are to evaluate the efficacy and safety of needle-free jet injections for dermatological indications and to provide evidence-based treatment recommendations. An electronic literature search was conducted in April 2022. Two reviewers independently selected studies based on predefined criteria and performed a methodological quality assessment using the Cochrane Collaborations risk-of-bias 2.0 assessment tool and Newcastle–Ottawa Scale. Thirty-seven articles were included, involving 1911 participants. Dermatological indications included scars, alopecia areata, hyperhidrosis, nail diseases, non-melanoma skin cancer, common warts, local anesthesia, and aesthetic indications. Keloids and other types of scars (hypertrophic, atrophic, and burn scars) were investigated most frequently (n = 7). The included studies reported favorable efficacy and safety outcomes for intralesional jet injector-assisted treatment with triamcinolone acetonide/hexacetonide, 5-fluorouracil, bleomycin, or hyaluronic acid. Two high-quality studies showed good efficacy and tolerability of intralesional jet injections with a combination of 5-fluorouracil and triamcinolone acetonide in hypertrophic scars and with saline in boxcar and rolling acne scars. No serious adverse reactions and good tolerability were reported in the included studies. Overall, the methodological quality of the included studies was low. Limited evidence suggests that needle-free jet injector-assisted intralesional treatment is efficacious and safe for hypertrophic and atrophic acne scars. More well-powered RCTs investigating the efficacy and safety of jet injector treatment in dermatology are warranted to make further evidence-based recommendations.
Graphical Abstract
Weather, ultrasonic, cranial and body traits predict insect diet hardness in a Central Mexican bat community
Authors: Ayala-Berdon Jorge , Martínez Gómez Margarita , Ponce Andrés Ramírez , Beamonte-Barrientos Rene , Vázquez Jorge , Rodriguez-Peña Olga Nelly 
Published: March 2023

AbstractInsectivorous bats exhibit food preferences for specific attributes in their prey. Hardness has been defined as an important prey attribute, and in some cases a limiting factor in foraging decisions for smaller compared to larger bat species. The goal of this study was to identify which factors influence the selection of prey hardness in a vespertilionid bat community. We investigated food consumed by bats by analyzing fecal samples obtained from eight bat species coexisting in a mountain ecosystem of central Mexico and correlate non-phylogenetically and phylogenetically prey hardness to weather, bat´s body, cranial and ultrasonic call structure variables. Results showed that diet of vespertilionid bats was mainly represented by Diptera, Neuroptera, Lepidoptera and Coleoptera consumption. The qualitative prey hardness index (From soft 1 to hard 5) ranked bats as:Myotis melanorhinus,Corynorhinus mexicanus,Myotis volans,Myotis californicus(< 3);Myotis velifer(< 4);Eptesicus fuscus,Idionycteris phyllotisandMyotis thysanodes(> 4.2). Prey hardness was positively correlated to minimum and mean temperatures, bat´s body weight, total and forearm lengths, cranial variables as: zygomatic breadth, mandibular length, height of the coronoid process, lower molar width, C-M3 superior and inferior rows length and upper molar width; and negatively to ultrasonic variables as total slope, call duration, low and high frequencies, band width and frequency maximum power. Considering phylogenies, prey hardness positively correlated to mandibular length, C-M3 inferior and superior rows lengths (p < 0.05). Our results showed that environmental, morphological and echolocation variables can be used as predictors of preferred insect prey in a community of vespertilionid bats.
Centers of Hecke algebras of complex reflection groups
Authors: Chavli Eirini , Pfeiffer Götz 
Published: March 2023

AbstractWe provide a dual version of the Geck–Rouquier Theorem (Geck and Rouquier in Finite Reductive Groups (Luminy, 1994), Progr. Math., vol. 141, Birkhäuser Boston, Boston, pp. 251–272, 1997) on the center of an Iwahori–Hecke algebra, which also covers the complex case. For the eight complex reflection groups of rank 2, for which the symmetrising trace conjecture is known to be true, we provide a new faithful matrix model for their Hecke algebra H. These models enable concrete calculations inside H. For each of the eight groups, we compute an explicit integral basis of the center of H.
In situ development of bacterial cellulose/hydroxyapatite nanocomposite membrane based on two different fermentation strategies: characterization and cytotoxicity evaluation
Authors: Saleh Ahmed K. , Tolba Emad , Salama Ahmed 
Published: March 2023

AbstractBacterial cellulose (BC) has garnered attention among biomaterial scientists for its unique physicochemical features and biocompatibility; however, the lack of bioactivity has limited its biomedical applications. Thus, this study describes the in situ preparation of BC/hydroxyapatite (HA) nanocomposite membranes using static and agitated fermentation to enhance the bioactivity of BC. The incorporation of HA increased BC production from 2.31 g/L without HA to 4.10 and 3.26 g/L under static and agitated fermentation, respectively, although the SEM observation indicates the formation of a fibrous structure in BC mesh under both fermentations. It was also observed that the content of HA nanoparticles in BC obtained from agitated fermentation was higher than that obtained from static fermentation. In addition, the average fiber diameter was increased from 56 ± 17 nm for agitated nanocomposites (BC/HA-A) to 145 ± 48 nm for static BC/HA nanocomposites (BC/HA-S) and 122 ± 26 nm for BC. In conclusion, the in situ formation of BC/HA nanocomposite under agitated fermentation appears more convenient in term of BC yield, HA content and distribution, and cytotoxicity against fibroblast cells (BJ1). This strategy will inspire new ways to prepare BC-based materials for medical applications.
Thermal decomposition characteristics and study of the reaction kinetics of tea-waste
Authors: Alashmawy Mohamad M. , Hassan Hassan S. , Ookawara Shinichi A. , Elwardany Ahmed E. 
Published: March 2023

AbstractThis study aimed to investigate waste-tea’s pyrolysis kinetics and thermodynamics to assess its potential for thermochemical processes. In this study, three primary samples of tea-waste are prepared for investigation: raw, torrefied at 200 °C, and torrefied at 600 °C. Under a nitrogen environment, thermogravimetric analyses (TGA) were conducted at seven heating rates (10, 15, 20, 25, 30, 35, and 40 °C/min) to investigate the effect of heating rates on the kinetic parameters at temperatures ranging from 27 to 1000 °C. Using seven heating rates was beneficial to take advantage of multiple heating rates techniques alongside single heating rate techniques. These heating rates were combined, forming four heating rate groups (HRG). The pyrolysis kinetic parameters are determined using two model-fit-methods, direct Arrhenius and Coats-Redfern methods, and two model-free methods, Flynn-Wall-Ozawa (FWO) and Kissinger-Akahira-Sunose (KAS) methods. Thermodynamic data comprising ΔH, ΔG, and ΔS are addressed. The X-ray fluorescence (XRF) and Fourier transform infrared (FTIR) spectrum are used to assess the presence of natural minerals in tea-waste. The results indicated that the tea-waste material has the potential to produce syngas. The torrefaction process at 600 °C shows a 53% increase in the energy content compared to the raw biomass. The Coats-Redfern is shown to be more reliable than the direct Arrhenius method. The activation energy (Ea) witnesses rising with the heating rate (β) from Ea = 55.27 kJ mol−1 at β = 10 °C min−1 to 60.04 kJ mol−1 at β = 40 °C min−1 for raw tea-waste using Coats-Redfern method. For model-free approaches, the minimum activation energy values of the raw tea-waste samples are 82 kJ/mol for FWO and 78 kJ/mol for KAS, whereas the peak values are 420 kJ/mol for KAS and 411 kJ/mol for FWO. A comparison of the effect of heating rate groups for FWO method in raw material case indicated that HRG1 has the maximum activation energy average value. The resulting values of HRG1, HRG2, HRG3, and HRG4 were 269 kJ/mol, 145 kJ/mol, 174 kJ/mol, and 202 kJ/mol, respectively.
Prognostic and functional roles of EIF4G1 in lung squamous cell carcinoma
Authors: Bai Baoxin , Dong Lin , Feng Minghao , Zhang Zhiwen , Lu Ying , Xu Zengguang , Liu Yali 
Published: March 2023

AbstractEukaryotic translation initiation factor 4 gamma 1 (EIF4G1) is highly expressed in many cancers and affects their occurrence and development. However, the effect of EIF4G1 on the prognosis, biological function and the relevant mechanism in lung squamous cell carcinoma (LSCC) is unclear. Through clinical cases, Cox’s proportional hazard model and Kaplan–Meier plotter survival analysis, we find the expression levels of EIF4G1 are dependent on age and clinical stage, high expression of EIF4G1 could be used to predict the overall survival of LSCC patients. LSCC cell line NCI-H1703, NCI-H226 and SK-MES-1infected with EIF4G1 siRNA are used to detect the function of EIF4G1 with cell proliferation and tumorigenesis in vivo and vitro. The data show that EIF4G1 promotes tumor cell proliferation and the G1/S transition of cell cycle in LSCC, then the biological function of LSCC is effected by the AKT/mTOR pathway. Above all, these results have demonstrated that EIF4G1 promotes LSCC cell proliferation and may represent an indicator of prognosis in LSCC.