bluuebunny/crossref_metadata_2025_split huggingface dataset:
STRATEGI KOMUNIKASI HUBUNGAN MASYARAKAT (HUMAS) PALANG MERAH INDONESIA (PMI) KOTA BIMA DALAM MENINGKATKAN KESADARAN MASYARAKAT UNTUK DONOR DARAH
Authors: Aini Annisya  
Published: March 2023

Penelitian ini berjudul Strategi Komunikasi Hubungan Masyarakat (Humas) Palang Merah Indonesia (PMI) Kota Bima Dalam Meningkatkan Kesadaran Masyarakat Untuk Donor Darah. Rumusan masalah yang diangkat dalam pembahasan ini yaitu, Bagaimana starategi komunikasi hubungan masyarakat (Humas) Palang Merah Indonesia (PMI) Kota Bima dalam meningkatkan kesadaran masyarakat untuk donor darah. Tujuan penelitian ini adalah untuk mengetahui starategi komunikasi hubungan masyarakat (Humas) Palang Merah Indonesia (PMI) Kota Bima dalam meningkatkan kesadaran masyarakat untuk donor darah.
Jenis penelitian ini adalah penelitian kualitatif. Berdasarkan analisis terhadaps sejumlah variable penelitian dengan menggunakan analisis deskriptif kualitatif, maka hasil penelitian yang diperoleh yaitu: Hubungan masyarakat atau Public relations adalah suatu usaha yang sengaja dilakukan, direncanakan secara berkesinambungan untuk menciptakan saling pengertian antara sebuah lembaga/institusi dengan masyarakat. Aktivitas public relations adalah menyelenggarakan komunikasi timbal balik antara lembaga dengan publik yang bertujuan untuk menciptakan saling pengertian dan dukungan bagi tercapainya suatu tujuan tertentu, kebijakan, kegiatan produksi, demi kemajuan lembaga atau citra positif organisasi dan tujuan organisasi terhadap membangun kesadaran masyarakat untuk melakukan donor darah.
Saran diajukan untuk menampung pendapat dan masukan dari masyarakat luas terhadap pelayanan dan fasilitas organisasi, akan lebih baik jika public relations PMI mengaktifkan forum internet atau website yang bisa diakses oleh masyarakat luas, tidak hanya di Indonesia saja tapi juga di dunia, sehingga bisa berguna untuk perbaikan dan peningkatan kualitas pelayanan dan informasi PMI selanjutnya.
Hepatoprotective Activity of 6-Heptadecylcyclohex -3-ene-1 Carboxylic Acid Isolated from the Methanol Extract of Dichrostachys cinerea Wight & Arn. Stem Bark
Authors: Babu P. Suresh , Krishna V. , Bhavya D. C. 
Published: March 2023

Aim of the Study: The phytoconstituent 6-heptadecylcyclohex 3-ene-1 carboxylic acid isolated from the methanol extract of Dichrotachys cinerea Wight. stem bark was evaluated for hepatoprotective activity against CCl4 induced toxicity.
Materials and Methods: The constituent 6-heptadecylcyclohex 3-ene-1 carboxylic acid isolated from the methanolic extract of D. cinerea and the structure was confirmed by spectroscopic studies. Hepatoprotective property was screened in male wistar strain rats. The parameters studied were estimation of liver function serum markers such as serum total bilirubin, total protein, alanine transaminase, aspartate transaminase, alkaline phosphatase and histological profile of the liver tissue.
Results: The LD50 of methanolic extract and constituent, 6-Heptadecylcyclohex -3-ene-1 carboxylic acid were evaluated and found to be 500 and 100 mg/kg body weight respectively. The hepatoprotective activity of constituent was more significant as similar to the standard hepatoprotective drug silymarin. The histological profile of the liver tissue showed the presence of normal hepatic cords, absence of necrosis and fatty infiltration as similar to the controls.
Conclusion: The methanolic extract of D. cinerea stem bark and the phytoconstituent 6-heptadecylcyclohex-3-ene-1 carboxylic acid showed significant protection from CCl4 induced liver damage.
Optimizing Cow Urine Application Rate at Varying Fertility and Zinc Levels on Wheat (Triticum aestivum L.) Productivity under Dairy Based Farming System in Varanasi Tract
Authors: Choudhary Sunita , Bohra J. S. , Jat Malchand 
Published: March 2023

This field investigation was carried out in two consecutive years of 2016-17 and 2017-18 at the Agricultural Research Farm, Banaras Hindu University, Varanasi (U.P.) to assess the effect of cow urine application at varying fertility and zinc levels on growth and yield of wheat (Triticum aestivum L.) under irrigated condition of Varanasi. Results showed that application of the fertilizer at 100% recommended dose of fertilizers (RDF) recorded significantly higher growth parameters viz. plant height, number of tiller m-1 row length; yield attributes viz. number of effective tiller m-2, spike length, grains spike-1 and test weight as well as grain and straw yield than 75% RDF during both the years. Among the zinc levels, zinc applied at 10 kg ha-1 though remained comparable to 5 kg Zn ha-1, recorded significantly higher values of these parameters over control. Cow urine at the rate of 12000 l ha-1 applied equally at sowing, CRI (Crown Root Initiation) and spike emergence (SE) stages gave higher values of plant height, number of tiller m-1 row length, spike length and number of grain spike-1 which being at par with 4000 l ha-1 cow urine each at sowing and CRI, both recorded significantly higher values than control. However, with respect to effective tillers m-2, grain and straw yield, significant increase was noticed with each increment of cow urine, recording maximum at 12000 l ha-1 during both the years.
Left Trans-thoracic Evisceration of a Perforated Transverse Colon
Authors: Atemkeng T. F. , Dongmo A. , Banga N. D. D. , Amougou B. , Mgamba K. , Leroy Guifo , Essomba A. , Nonga Ngo , Mikande Ze , Djam C. A. 
Published: March 2023

We received a 31 years old male who presented to the emergency after been stabbed on both thorax. The left thoracic wound was the site of evisceration of colon. The eviscerated colon was perforated. The patient was instable. After stabilisation, he was operated under general anesthesia. A bilateral thoracic drainage done,one and the right thoracic stab wound was then closed. A median laparotomy discovered the left colic herniation through the left diaphragmatic coupole, continuing through the thorax by the evisceration and a gastric tear. The colon was wached and reduced first through the abdomen by gentle traction. The left parietal wound was then closed. The left thorax cavity was washed and the diaphragmatic hole closed. The left transverse colonic tear was excised and closed. He stayed 5 days in the intensive care unit. We had a superficial site infection of the laparotomy wound treated by saline wet dressing for 20 days. After one month hospitalisation, the patient was discharged. He resumed his work after 3 months and is doing well at 12 months postoperative. This case emphasizes on a rare surprise awaiting the trauma surgeon.
Silicon Uptake Mechanism and its Multidimensional Influences on Stress Mitigation in Rice (Oryza sativa L.)
Authors: Ashokan Akhila , Anand S. , Aparna B. , Mini V. 
Published: March 2023

Silicon (Si) is the second most abundant element in the earth crust constituting 27.7 per cent. The beneficial effects of Si includes mitigation of various forms of abiotic and biotic stresses. Rice (Oryza sativa), a typical Si accumulator, takes up Si actively in the form of silicic acid. There are three transporters involved in the uptake of Si viz, LSi1, LSi2 and LSi3. Influx transporter (LSi1) takes up silicic acid from soil solution and mediates its transport upto the exodermal layer of root system, followed by the efflux transporter (LSi2), which transports it across the aerenchyma. Further movement of Si to the aerial parts of the plant is mediated by another influx transporter, LSi6 and finally gets deposited as silica in the plant parts. Silicon present in soil solution as well as its deposition in plants helps in mitigating various stresses in rice. Si application during drought stress prevents compression of xylem vessels and thereby resulting in reduction of transpiration rate. Sufficient supply of Si stabilises the culms and serves to decrease the risk of lodging. Rice is sensitive to metal toxicities like Iron (Fe), Manganese (Mn) and Aluminium (Al). Si complexation with these metal ions decreases their translocation rate and reduces the toxic effects. Heavy metal toxicity due to accumulation of cadmium (Cd) and arsenic (As) can be alleviated through supplementation of Si. Si also ameliorates salt stress by decreasing Na uptake and its root-to-shoot translocation. Silicon deposition in plant parts provides a mechanical barrier against pathogens and pests. The plants supplied with Si produce phenolics and phytoalexins in response to fungal infection and cuticle-Si double layer act as a defence mechanism preventing pests. The key mechanisms of Si-mediated alleviation of stresses in rice include stimulation of antioxidants, complexation of toxic metal ions with Si, immobilization of toxic metal ions and compartmentation of metal ions within plants.
Multivariate analysis of selected agro-morphological traits of common wheat genotypes for estimation of genetic diversity
Authors: Bibi Sadaf , Inamulla Inamulla , Qayyum Abdul 
Published: March 2023

Estimation of genetic diversity of plant species using agro morphological parameters is of very crucial importance in plant improvement programs. In view of that common wheat (Triticum aestivum L.) genotypes consisting of stripe rust resistant genes were analyzed by cluster analysis, principle component analysis and coefficient of correlation analysis for determination of genetic diversity. Experiment was conducted in fields of Hazara University Mansehra Pakistan. Eight groups were categorized by cluster analysis using UPGMA clustering method. AOC-YR/ATTILA (CGSS97Y0061S-23Y-1B-1B) (Sdf31) and 10790 (sdf2) are reported as more diversified by cluster analysis. Based on principal component analysis the first five clusters showed 88.94% of genetic variation. Grains per spike contributed more (0.7) to total variation in PCI. While Harvest Index was the major contributor (0.8) to total variation in PCII. 1056 (Sdf5), AOC-YR/ATTILA (CGSS97Y0061S-32Y-1B-1B) (sdf30), 1072 (sdf6), 1076 (sdf9), and LALBMONO4*4/PRL//LALB (CGSS99Y00093S-2F1-22Y-9GHB-1GHB) (sdf32) were observed superior in flag leaf area, spike length, grains per spike, plant height, biological yield, plant yield and harvest index. AOC-YR/ATTILA (CGSS97Y0061S-32Y-1B-1B) (Sdf30) was found as early maturing genotype. Correlation analysis showed positive and significant association of plant yield with flag leaf area, spike length and biological yield, while it is highly negatively correlated to no. of days to maturity. More diversified genotypes identified in this studies can be used in future breeding programs along with utilization of superior genotypes in hybridization.
Key words: cluster analysis, correlation, genetic diversity, principal component analysis, whea
Stiffness and strength evaluation of prestressed timber beam with unbonded steel Strand and reinforced concrete Beam‐Column joint
Authors: Shirayama Takashi , Satou Nozomi , Tokutake Shigetaka 
Published: March 2023

AbstractThe deformation behavior of prestressed timber beams after a gap opens at the beam‐column interface is evaluated in this study using the compressive stress distribution along the beam length. The correlation between moment at the beam end and beam deformation is studied for three types of specimens. The evaluation results indicate that the prediction is in good agreement with the experimental results up to the proportional limit of the material. In addition, the bending ultimate strength calculated using the compressive stress distribution at the beam end, which is obtained from the compressive stress–strain relationship, is also verified with the values of moments in the experiment. Finally, an alternative elastic element model with a quadrilinear rigid‐plastic spring at the element end was proposed.
Oxyanion Engineering Suppressed Iron Segregation in Nickel–Iron Catalysts Toward Stable Water Oxidation
Authors: Liao Hanxiao , Ni Ganghai , Tan Pengfei , Liu Kang , Liu Xuanzhi , Liu Hele , Chen Kejun , Zheng Xusheng , Liu Min , Pan Jun 
Published: March 2023

AbstractNickel–iron catalysts represent an appealing platform for electrocatalytic oxygen evolution reaction (OER) in alkaline media because of their high adjustability in components and activity. However, their long‐term stabilities under high current density still remain unsatisfactory due to undesirable Fe segregation. Herein, a nitrate ion (NO3−) tailored strategy is developed to mitigate Fe segregation, and thereby improve the OER stability of nickel–iron catalyst. X‐ray absorption spectroscopy combined with theoretical calculations indicate that introducing Ni3(NO3)2(OH)4 with stable NO3− in the lattice is conducive to constructing the stable interface of FeOOH/Ni3(NO3)2(OH)4 via the strong interaction between Fe and incorporated NO3−. Time of flight secondary ion mass spectrometry and wavelet transformation analysis demonstrate that the NO3− tailored nickel–iron catalyst greatly alleviates Fe segregation, exhibiting a considerably enhanced long‐term stability with a six‐fold improvement over FeOOH/Ni(OH)2 without NO3− modification. This work represents a momentous step toward regulating Fe segregation for stabilizing the catalytic performances of nickel–iron catalysts.
Photoinduced Radical Cyclization of 1,6‐Diynes: Rapid Access to Highly Substituted Carbocyclic and Heterocyclic Compounds
Authors: Reddy Mutra Mohana , Chen Yu‐Ting , Wang Jeh‐Jeng 
Published: March 2023

AbstractWe have developed photoinduced sulfonyl radical‐triggered cyclization of 1,6‐dynes without metals, oxidants, or additives. During the reaction, three new bonds are formed (−SO2−C, C−C, and C−I/C−Se−) under mild conditions, with excellent selectivity. The conversion is temporally and atomically economical and is easy to handle even on a gram scale. Detailed mechanistic studies showed that the reaction proceeds via a radical pathway. Subsequent synthetic transformations of the new products produced various substituted compounds. Importantly, we observed an unprecedented and selective C−C single bond cleavage with boronic acid insertion under Suzuki reaction conditions.magnified image
Tissue iron distribution in patients with anemia of inflammation: Results of a pilot study
Authors: Lanser Lukas , Plaikner Michaela , Schroll Andrea , Burkert Francesco Robert , Seiwald Stefanie , Fauser Josia , Petzer Verena , Bellmann‐Weiler Rosa , Fritsche Gernot , Tancevski Ivan , Duftner Christina , Pircher Andreas , Seeber Andreas , Zoller Heinz , Kremser Christian , Henninger Benjamin , Weiss Günter 
Published: March 2023

AbstractAnemia of inflammation (AI) is frequently present in subjects with inflammatory disorders, primarily caused by inflammation‐driven iron retention in macrophages. So far, only limited data on qualitative and quantitative estimates of tissue iron retention in AI patients exist. We performed a prospective cohort study analyzing splenic, hepatic, pancreatic, and cardiac iron content with MRI‐based R2*‐relaxometry in AI patients, including subjects with concomitant true iron deficiency (AI+IDA) hospitalized between 05/2020–01/2022. Control groups were individuals without inflammation. Spleen R2* values in AI patients with ferritin ≤200 μg/L (AI+IDA) were comparable with those found in controls. In AI patients with ferritin >200 μg/L, spleen (47.6 s−1 vs. 19.3 s−1, p < .001) and pancreatic R2* values (32.5 s−1 vs. 24.9 s−1, p = .011) were significantly higher compared with controls, while liver and heart R2*‐values did not differ. Higher spleen R2* values were associated with higher ferritin, hepcidin, CRP, and IL‐6 concentrations. Spleen R2* values normalized in AI patients after recovery (23.6 s−1 vs. 47.6 s−1, p = .008), while no changes were found in patients with baseline AI+IDA. This is the first study investigating tissue iron distribution in patients with inflammatory anemia and AI with concomitant true iron deficiency. The results support the findings in animal models demonstrating iron retention in macrophages, which are primarily accumulating in the spleen under inflammatory conditions. MRI‐related iron measurement may help to better characterize actual iron needs and to define better biomarker thresholds in the diagnosis of true ID in patients with AI. It may qualify as a useful diagnostic method to estimate the need for iron supplementation and to guide therapy.
Prevalence of suspected dementia in a sample of adults living in Kinshasa‐Democratic Republic of the Congo
Authors: Ikanga Jean , Reyes Anny , Kaba Didine , Akilimali Pierre , Mampunza Samuel , Epenge Emmanuel , Gikelekele Guy , Kavugho Immaculee , Tshengele Nathan , Hammers Dustin B. , Alonso Alvaro 
Published: March 2023

AbstractBackgroundThe prevalence of dementia in Sub‐Saharan Africa, particularly in French‐speaking countries, has received limited attention. This study investigates the prevalence and risk factors of suspected dementia in elderly adults in Kinshasa, Democratic Republic of the Congo (DRC).MethodsA community‐based sample of 355 individuals over 65 years old was selected using multistage probability sampling in Kinshasa. Participants were screened using the Community Screening Instrument for Dementia, Alzheimer's Questionnaire, Geriatric Depression Scale, Beck Anxiety Inventory, and Individual Fragility Questionnaire, followed by clinical interview and neurological examination. Suspected dementia diagnoses were made based on the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM‐5) criteria including significant cognitive and functional impairments. Prevalence and odds ratios (ORs) with 95% confidence interval (CI) were calculated using, respectively, regression and logistic regression.ResultsAmong 355 participants (mean age 74, SD = 7; 51% male), the crude prevalence of suspected dementia was 6.2% (9.0% in women and 3.8% in men). Female sex was a significant factor associated with suspected dementia [OR = 2.81, 95% CI (1.08–7.41)]. The prevalence of dementia increased with age (14.0% after 75 years and 23.1% after 85 years), with age being significantly associated with suspected dementia [OR = 5.42, 95% CI (2.86–10.28)]. Greater education was associated with a lower prevalence of suspected dementia [OR = 2.36, 95% CI (2.14–2.94), comparing those with ≥7.3 years of education to those with <7.3 years of education]. Other factors associated with the prevalence of suspected dementia included being widowed (OR = 1.66, 95% CI (1.05–2.61), being retired or semi‐retired (OR = 3.25, 95% CI (1.50–7.03)], a diagnosis of anxiety [OR = 2.56, 95% CI (1.05–6.13)], and death of a spouse or a relative after age 65 [OR = 1.73, 95% CI (1.58–1.92)]. In contrast, depression [OR = 1.92, 95% CI (0.81–4.57)], hypertension [OR = 1.16, 95% CI (0.79–1.71)], body mass index (BMI) [OR = 1.06, 95% CI (0.40–2.79)], and alcohol consumption [OR = 0.83, 95% CI (0.19–3.58)] were not significantly associated with suspected dementia.ConclusionsThis study found a prevalence of suspected dementia in Kinshasa/DRC similar to other developing countries and Central African countries. Reported risk factors provide information to identify high‐risk individuals and develop preventive strategies in this setting.
Protein Oligomer Engineering: A New Frontier for Studying Protein Structure, Function, and Toxicity
Authors: Liu Chang , Luo Jinghui 
Published: March 2023

AbstractPrevalent in nature, protein oligomers play critical roles both physiologically and pathologically. The multimeric nature and conformational transiency of protein oligomers greatly complicate a more detailed glimpse into the molecular structure as well as function. In this minireview, the oligomers are classified and described on the basis of biological function, toxicity, and application. We also define the bottlenecks in recent oligomer studies and further review numerous frontier methods for engineering protein oligomers. Progress is being made on many fronts for a wide variety of applications, and protein grafting is highlighted as a promising and robust method for oligomer engineering. These advances collectively allow the engineering and design of stabilized oligomers that bring us one step closer to understanding their biological functions, toxicity, and a wide range of applications.
Toward Scalable Nanofluidic Osmotic Power Generation from Hypersaline Water Sources with a Metal–Organic Framework Membrane
Authors: Pan Shangfa , Liu Peng , Li Qi , Zhu Bin , Liu Xueli , Lao Junchao , Gao Jun , Jiang Lei 
Published: March 2023

AbstractNanofluidic membranes have shown great promise in harvesting osmotic energy but its scalablity remains challenging since most studies only tested with a membrane area of ≈10−2 mm2 or smaller. We demonstrate that metal‐organic‐framework membranes with subnanometer pores can be used for scalable osmotic power generation from hypersaline water sources. Our membrane can be scaled up to a few mm2, and the power density can be stabilized at 1.7 W m−2. We reveal that the key is to improve the out‐of‐membrane conductance while keeping the membrane's charge selectivity, contradicting the previous conception that the ionic conductivity of the membrane plays the dominating role. We highlight that subnanometer pores are essential to ensure the charge selectivity in hypersaline water sources. Our results suggest the importance to engineer the interplay between the in‐membrane and out‐of‐membrane ion transport properties for scalable osmotic power generation.
Lattice Mismatch Guided Nickel‐Indium Heterogeneous Alloy Electrocatalysts for Promoting the Alkaline Hydrogen Evolution
Authors: Mondal Surajit , Dutta Supriti , Mal Santanu , Pati Swapan K. , Bhattacharyya Sayan 
Published: March 2023

AbstractThe immiscibility of crystallographic facets in multi‐metallic catalysts plays a key role in driving the green H2 production by water electrolysis. The lattice mismatch between tetragonal In and face‐centered cubic (fcc) Ni is 14.9 % but the mismatch with hexagonal close‐packed (hcp) Ni is 49.8 %. Hence, in a series of Ni−In heterogeneous alloys, In is selectively incorporated in the fcc Ni. The 18–20 nm Ni particles have 36 wt % fcc phase, which increases to 86 % after In incorporation. The charge transfer from In to Ni, stabilizes the Ni0 state and In develops a fractional positive charge that favors *OH adsorption. With only 5 at% In, 153 mL h−1 H2 is evolved at −385 mV with mass activity of 57.5 A g−1 at—400 mV, 200 h stability at −0.18 V versus reversible hydrogen electrode (RHE), and Pt‐like activity at high current densities, due to the spontaneous water dissociation, lower activation energy barrier, optimal adsorption energy of OH− ions and the prevention of catalyst poisoning.
Isolation of Structurally Heterogeneous TCR‐CD3 Extracellular Vesicle Subpopulations Using Caliper Strategy
Authors: Yin Wen , Chen Haitian , Cai Jianye , Huang Xing , Zhang Lang , Xu Yuzhi , Zheng Jun , Liu Si‐Yang , Zou Xiaoyong , Dai Zong , Yang Yang 
Published: March 2023

AbstractCells in different states can release diverse types of extracellular vesicles (EVs) that participate in intracellular communication or pathological processes. The identification and isolation of EV subpopulations are significant to explore their physiological functions and clinical value. In this study, structurally heterogeneous T‐cell receptor (TCR)‐CD3 EVs were proposed and verified for the first time using a caliper strategy. Two CD3‐targeting aptamers were designed in the shape of a caliper with an optimized probe distance and were assembled on gold nanoparticles (Au‐Caliper) to distinguish TCR‐CD3 monomeric and dimeric EVs (m/dCD3 EVs) in skin‐transplanted mouse plasma. Phenotyping and sequencing analysis revealed clear heterogeneity in the isolated m/dCD3 EVs, providing the potential for mCD3 EVs as a candidate biomarker of acute cellular rejection (ACR) and holding great prospects for distinguishing EV subpopulations based on protein oligomerization states.