bluuebunny/crossref_metadata_2025_split huggingface dataset:
Phenotypic Variability and Management of Patients with Mosaic monosomy X and Y chromosome material: A Case Series.
Authors: Fredj Myriam Ben , messaoud marwa , Youssef sabrine Ben , Mani salma , laaribi syrine , Sakka Rania , Hmida Hayet Ben , ksiaa amine , mekki mongi , Belghith mohsen , sahnoun lassaad 
Published: August 2023

Abstract

Background we aim to discuss the origin and the differences of the phenotypic features and the management care of rare form of disorder of sex development due to Mosaic monosomy X and Y chromosome materiel.Methods We report our experience with patients harboring mosaic monosomy X and Y chromosome material diagnosed by blood cells karyotypes and cared for in our department from 2005 and 2022.Results We have included five infants in our study. The current average age was 8 years. In four cases, the diagnosis was still after born and it was at the age of 15 years in one case. Physical examination revealed a variable degree of virilization, ranging from a normal male phallus with unilateral ectopic gonad to ambiguous with a genital tubercle and bilateral not palpable gonads in four cases and normal female external genitalia in patient 5. Karyotype found 45, X/46, XY mosaicism in patient 1 and 2 and 45, X/46, X, der (Y) mosaicism in patient 3, 4 and 5. Three cases were assigned to male gender and two cases were assigned to female. After radiologic and histologic exploration, four patients had been explored by laparoscopy to perform gonadectomy in two cases and Mullerian derivative resection in the other. Urethroplasty was done in two cases of posterior hypospadias. Gender identity was concordant with the sex of assignment at birth in only 3 cases.Conclusion Because of the phenotypic heterogeneity of this sexual disorders and the variability of its management care, then the decision should rely on a multidisciplinary team approach.
Inhibitory effect of curcumin on Human carbonic anhydrase II glycation:In vitro and docking studies
Authors: Tari Zeinab , Khatibi Ali , Dashtestani Fariba , Adib Atoosa , Alijanianzadeh Mahdi , Shadfar Najmeh 
Published: August 2023

Abstract
Glycation is a non-enzymatic reaction between the aldehyde group of a sugar and the amino group of a protein, which causes structural and functional changes in the protein as well as the production of advanced glycation end products (AGEs). The negative impact of AGEs-related damage on proteins are reactive oxygen species production that cause complications in diabetic patients. Here, in this study the inhibition of glycation of human carbonic anhydrase enzyme (HCA) by curcumin as an antioxidant was investigated. The inhibition of AGE by curcumin on functional and structural changes of HCA was declared by UV-Vis spectroscopy, fluorescence, circular dichroism and docking study was then performed to observation the interaction between curcumin and the enzyme. For better investigating the effect of curcumin on HCA glycation process two incubation time were inspected; the curcumin was incubated with glycated HCAII 40 minutes prior to assay, and the simultaneous incubation of curcumin, D-glucose and HCAII. The results showed that curcumin improved the structure of HCA that had been changed by glycation and reduced the glycation of the HCAII. Moreover, the curcumin could restore the structure of the HCAII to normal in 40 minutes incubation. Based on the results of this study, it seems that curcumin can be used as a drug candidate for the treatment of diabetes.
Boosting photocatalytic H2 evolution on UIO-66-NH2/covalent triazine-based frameworks composites by constructing a covalent heterojunction
Authors: DONG Shiwen , LIU Xuan , KONG Xianxian , DONG Feilong , YU Yan , WANG Lizhang , WANG Da , HE Zhiqiao , SONG Shuang 
Published: August 2023

Abstract
Metal-organic frameworks (MOFs) and covalent organic frameworks (COFs) have been proved as efficient catalysts for photocatalytic H2 evolution, thanks to their tunable functionalities, permanent porosity, excellent visible light response, as well as physicochemical stability. Herein, a series of photocatalysts (termed NUBC) were fabricated by loading different amounts of Zr-UiO-66-NH2 (NU) onto a benzoic acid modified covalent triazine-based framework (BC) based on post-synthetic covalent modification. The resulting NUBC catalysts exhibited a type-II Z-scheme heterojunction structure formed via the amide covalent bonds between the amine groups on NU and carboxyl groups on BC. The optimal loading of NU on BC is 30 wt.% (30NUBC) and the corresponding photocatalytic H2 evolution rate was 378 μmol  h−1 g−1, almost 445 and 2 times than that of NU and BC, respectively. The synergistic effect between the type-II Z-scheme heterojunctions and amide bonds was conducive to boosting visible light harvesting and facilitating charge transportation and separation. Furthermore, the prepared NUBC catalysts show great reusability and stability. Overall, this work sheds light on the design of novel MOFs/COFs hybrid materials and provides a systematic exploration of their photocatalytic H2 evolution properties.
Upward social comparison on network and alcohol dependence in college students: The chain mediation impacts of relative deprivation and anxiety
Authors: Li Shuna , Zhang Kaijie , Kong Kaizhen , Niu Hua , Jiang Zhenli , Guo Hongbo 
Published: August 2023

Abstract

Background: Nowadays, contemporary society has placed growing emphasis on the alcohol drinking behavior of adolescents.
Methods: This study employed a cross-sectional design to assess the relation between upward social comparison (USC) on network and adolescent drinking behavior, while exploring the mediation impact of relative deprivation (RD) and anxiety. A total of 329 adolescents (Mage =21.38 years old; 16.10% females) were enrolled to complete a set of questionnaires evaluating USC on network, RD, anxiety and alcohol dependence.
Results: The results showed that (1) USC on network, RD, anxiety and alcohol dependence were significantly, positively correlated in pairs, and (2) RD and anxiety exhibited a significant chain mediating role between USC on network and alcohol dependence, and USC on network positively predicted alcohol dependence via the mediating effect of anxiety.
Conclusions: This study reveals that USC on network positively predicts alcohol dependence via the mediating effect of anxiety, and that RD and anxiety play a chain-mediating role between USC on network and alcohol dependence.
Kinetic Estimation of Fischer-Tropsch Synthesis using Biogas-derived Feedstocks over Ni/Al2O3 Catalyst
Authors: Alawi Nabil Majd , AL-Zuhairi Firas Khaleel , Minh Hoang Nguyen , Al-Mohammedawi Hassan H. , Alrubaye Jamal M. Ali 
Published: August 2023

Abstract
In this study, the kinetics of the Fischer-Tropsch process (also known as FTS) were investigated using feedstocks produced from biogas. For the kinetic testing, a differential fixed-bed reactor was utilized to operate the Ni/Al2O3 catalyst produced using precipitation procedures. Experiments were carried out with a variety of settings for the working circumstances, such as reaction temperatures ranging from 543 to 563 °K, H2:CO ratios ranging from 0.5 to 3, a pressure of 3.0 megapascals, with (GHSV) a gas hourly space velocity of 3500 (1/h). The reaction kinetics within this range of conditions can be modelled in a precise and accurate way thanks to the derived kinetic parameters. The FT reaction hypothesized mechanism uses the Langmuir-Hinshelwood-Hougen-Watson theory, which predicts that carbon monoxide and hydrogen will have an adsorption behaviour. The kinetic data obtained in this investigation were effectively modelled using a straightforward equation, which is as follows: \({- r}_{CO}=\frac{k.{P}_{CO}^{n}.{P}_{{H}_{2}}^{m}}{{(1+K.({a}_{CO}.{P}_{CO}^{n}+{a}_{{H}_{2}}.{P}_{{H}_{2}}^{m})}^{2}}.\) This model implies that essential kinetic processes, such as CO dissociation by contact with adsorbed hydrogen, have already occurred. The first stage in the hydrogenation process is presumed to be fast and reversible, whereas the second step is presumed to be sluggish and rate-determining.
Accessory genes in tropical race 4 contributed to the recent resurgence of the devastating disease of Fusarium wilt of banana
Authors: Ma Li-Jun , Zhang Yong , Li Chunyu , Liu Siwen , Liu Cunwu , Mostert Diane , Yu Houlin , Haridas Sajeet , Webster Katie , Li Minhui , Grigoriev Igor , Viljoen Altus , Yi Ganjun 
Published: August 2023

Abstract

Fusarium wilt of banana, caused by Fusarium oxysporum f. sp. cubense (Foc), is one of the most damaging plant diseases recorded. Foc race 1 (R1) decimated the Gros Michel–based banana trade. Currently, tropical race 4 (TR4) is threatening the global production of its replacement cultivar, Cavendish banana. Population genomics and phylogenetics revealed that all Cavendish banana–infecting race 4 strains shared an evolutionary origin that is distinct from R1 strains. The TR4 genome lacks accessory or pathogenicity chromosomes, reported in other F. oxysporum genomes. Accessory genes—enriched for virulence and mitochondrial-related functions—are attached to ends of some core chromosomes. Meta-transcriptomics revealed the unique induction of the entire mitochondria-localized nitric oxide (NO) biosynthesis pathway upon TR4 infection. Empirically, we confirmed the unique induction of NO burst in TR4,suggesting the involvement of nitrosative pressure in its virulence. Targeted mutagenesis demonstrated the functional importance of accessory genes SIX1 and SIX4 as virulent factors.
Tracing botanical origins of unifloral Aroeira honey with Geographical Indication: Anacardiaceae pollen characterization from northern Minas Gerais’ Seasonally Dry Tropical Forest and Cerrado.
Authors: Luz Cynthia Fernandes Pinto da , Sakugawa Gabriela Cristina , Gardoni Lívia Cristina de Paiva , Santana Rânia Mara , Bandeira Otávio Henrique Silva , Silva-Luz Cíntia Luíza da , Pirani José Rubens , Calaça Paula 
Published: August 2023

Abstract
Many species of Anacardiaceae from the Seasonally Dry Tropical Forest biome and Cerrado, an ecoregion of the Brazilian Tropical Savanna biome, are of great importance as a source of nectar and pollen. They are trees that massively bloom and attract several insects as floral visitors, especially honeybees and stingless bees. We aim to provide a practical tool for use in melissopalynological analyses of honeys, especially those produced in the northern region of Minas Gerais, Brazil. Here, a palynological description of six species of Anacardiaceae occurring in both vegetation types is provided using light and scanning electron microscopy. Statistical analyses were performed with the morphometric data to test the relevance of pollen morphology for defining pollen types and assisting in the certification of the botanical origin of honeys through melissopalynology. The most important metric variables for identifying the analyzed species were a combination of pollen grain size and width of the colpus margo, whereas pollen shape and other variables were less informative due to great intraspecific variation. Spondias tuberosa, with the largest pollen grains, stood out from the other species. The margo of the colpus wide contributed to the distinction of Schinopsis brasiliensis pollen grains. Qualitative traits analysis based on the pollen wall ornamentation contributed greatly to revealing two distinct groups: suprastriato-inframicroreticulate [Astronium fraxinifolium, A. graveolens, A. urundeuva, Schinopsis brasiliensis] and striate-perforate [Schinus terebinthifolia, Spondias tuberosa]. The palynological variation found among the studied species reinforces the importance of pollen morphology for the correct certification of botanical origin of Brazilian Aroeira honey.
Anti-Kasha Triplet Energy Transfer: Excitation Wavelength Dependent Persistent Luminescence from Host-Guest Doping Systems
Authors: Li Bingshi , Xie Weiwei , Huang Wenbin , Li Jietai , He Zikai , Huang Guangxi , Tang Ben Zhong 
Published: August 2023

Abstract
Anti-Kasha’s emission in organic luminogens has attracted many attentions since its discovery. However, only limited examples of anti-Kasha rule have been reported and anti-Kasha triplet energy transfer (ET) is even less-touched. This work provided an efficient strategy to realize excitation wavelength dependent (Ex-De) afterglow in a host-guest system benefiting from anti-Kasha rule. Host has almost imperceptible RTP upon 365 nm excitation and guest is totally RTP inactive, while the doping system exhibits Ex-De afterglow with improved quantum yields. Anti-Kasha triplet ET process is demonstrated from the higher excited triplet state T2 of host to the lowest excited singlet state S1 of the aggregated/unimolecular state of guest. ET efficiency in the doping system could be tuned by adopting denser or looser intermolecular packing through simply changing processing methods. The strategy of anti-Kasha triplet ET endows doping system with multiple stimuli-responsive properties, including Ex-De afterglow, mechano- and thermal-triggered afterglow behavior. Corresponding applications are also realized in multiple information anti-counterfeiting and display.
Distinctive pattern of serum trace elements and vitamin D levels in adolescents who stutter
Authors: Almudhi Abdulaziz , Gabr Sami A. 
Published: August 2023

Abstract

Objectives This study aims to investigate the potential effects of serum trace elements and vitamin D levels on cognitive capacity and stuttering symptoms in adolescents. So, we will determine the serum levels of Iron (Fe), Manganese (Mn), Selenium (Se), copper (Cu), and zinc (Zn), vitamin D levels, and cognitive capacity scores and their association with the severity of stuttering scores among adolescences aged 10–18 years’ old. Methods The study included 100 adolescence aged 10–18 years’ old. Stuttering severity, cognitive capacity, as well as vitamin D levels, and serum trace elements were identified using stuttering severity instrument (SSI-4; 4th edit.), the LOTCA-7 scores, immunoassay system, and spectrophotometer analysis respectively. Results the results showed that stuttering was identified in 60% of the participants they were classified into students with mild (n = 30; 19.6 mean) and moderate stuttering (28.7 mean, n = 30) respectively. Only 40% of the students had a total stuttering score within normal range with 11.6 mean stuttering score. Obesity related markers such as BMI, WHR showed significant association with the severity of stuttering compared to normal controls. In addition, the decline in cognitive capacity showed to be significantly increased in adolescences in association with mild to moderate stuttering as well. Also, serum trace elements (Fe, Mn, Se, Cu, Zn, Cu/Zn ratio) and vitamin D levels as biochemical parameters were significantly reduced in adolescences with mild to moderated stuttering than normal subjects. The reduction is closely increased in correlation with an increment in the severity of stuttering. Males showed comparable results than females of the same group signifying that gender could play a role in the stuttering severity as differences in vitamin D, serum trace element contents in the serum of both gender. Conclusion This study found significant associations between the severity of stuttering, trace elements, vitamin D deficiencies, and cognitive function in adolescents. Both deficiencies of trace elements and vitamin D along with cognitive impairment may potentially be more helpful and preventable causes of stuttering among school students aged 12–18 years. The studied parameters could be of diagnostic potential and helpful in the treatment of stuttering. However, deeper knowledge of mechanisms is needed in order to draw policy conclusions and public health guidelines to determine the roles of serum trace elements and vitamin D levels in the pathogenesis of stuttering.
Digital Media Art and Visual Communication Design Under the Background of Artificial Intelligence Research on Innovation Development
Authors: Meng Kun , Liu Fulong 
Published: August 2023

Abstract
With the fast develo China's science and technology, artificial intelligence and information technology have been used widely to enhance expression of human sentiments and the speed of information transmission, as well as to create digital media art. As a result of the advancements in digital media art, visual communication design (VCD) has undergone substantial transformations, and it is imperative that the designers responsible adapt VCD to these changes in order to enhance the design impact. This article examines the evolution and creativity of VCD in the context of digital media art, using AI as a backdrop. Initially the digital media art dataset is collected and the raw image data is preprocessed using normalization method. The preprocessed 2D data is converted to 3D using Selective Deep Generative Adversarial Network (SD-GAN). To enhance the quality of the visual design we use Particle Swarm Optimization (PSO) algorithm. The performance of the recommended system is analyzed and compared with conventional approaches to prove the efficacy of the proposed system.
Assessing urban livability in Shanghai through an open source data-driven approach
Authors: Gasparatos Alexandros , Long Yin , Wu Yi , Huang Liqiao , Aleksejeva Jelena , Iossifova Deljana , Dong Nannan 
Published: August 2023

Abstract

Urban livability has become a major policy and practice priority in many parts of the world, but its attainment remains challenging in many cities of developing and emerging economies. The lack of data with appropriate quality, coverage, and spatial/temporal resolution often complicates the assessment of livability in such cities, and the identification of priority areas for improvement. Here we develop an innovative framework to mobilize and synthesize open-source data to analyze spatially urban livability patterns in Shanghai. The framework brings together diverse open-source data such as housing prices, population distribution, transportation networks, and points of interest to identify city areas with low livability, and thus priority areas for improvement. Such findings can provide a comprehensive overview of the residential living environment in Shanghai, as well as provide useful information to urban planners and decision-makers. Furthermore, the developed method has the potential for application in other cities, subject to data availability.
Comparative Performance of Humans Versus GPT-4.0 and GPT-3.5 in the Self-assessment Program of American Academy of Ophthalmology
Authors: Taloni Andrea , Borselli Massimiliano , Scarsi Valentina , Rossi Costanza , Coco Giulia , Scorcia Vincenzo , Giannaccare Giuseppe 
Published: August 2023

Abstract
To compare the performance of humans, GPT-4.0 and GPT-3.5 in answering multiple-choice questions from the American Academy of Ophthalmology (AAO) Basic and Clinical Science Course (BCSC) self-assessment program, available at https://www.aao.org/education/self-assessments. In June 2023, text-based multiple-choice questions were submitted to GPT-4.0 and GPT-3.5. The AAO provides the percentage of humans who selected the correct answer, which was analyzed for comparison. All questions were classified by 10 subspecialties and 3 practice areas (diagnostics/clinics, medical treatment, surgery). Out of 1023 questions, GPT-4.0 achieved the best score (82.4%), followed by humans (75.7%) and GPT-3.5 (65.9%), with significant difference in accuracy rates (always P < 0.0001). Both GPT-4.0 and GPT-3.5 showed the worst results in surgery-related questions (74.6% and 57.0% respectively). For difficult questions (answered incorrectly by > 50% of humans), both GPT models favorably compared to humans, without reaching significancy. The word count for answers provided by GPT-4.0 was significantly lower than those produced by GPT-3.5 (160 ± 56 and 206 ± 77 respectively, P < 0.0001); however, incorrect responses were longer (P < 0.02). GPT-4.0 represented a substantial improvement over GPT-3.5, achieving better performance than humans in an AAO BCSC self-assessment test. However, ChatGPT is still limited by inconsistency across different practice areas, especially when it comes to surgery.
Spatiotemporal variation in phenology of the invasive brown macroalga Sargassum muticum (Yendo) Fensholt and the environmental parameters relationships along four different sites in the Atlantic coast of Morocco
Authors: Aamiri Abderrahmane , Bellahcen Touria Ould , Pereira Leonel , Benhniya Bouchra , Zidane Hakima , Rezzoum Nor-Eddine 
Published: August 2023

Abstract

The alien brown seaweed Sargassum muticum (Yendo) Fensholt is currently observed along the coasts of Morocco. The present study aimed to evaluate the impact of physicochemical parameters on the distribution of S. muticum at four sites on the Atlantic coast of Morocco harvested between 2019 and 2020. This study’s results showed that the highest biomass, thalli length and fertility values were recorded in sampling sites characterized by optimal physicochemical (temperature, pH and salinity) and nutrient H₃PO₄ during summer. The highest biomass values were recorded in August for Sidi Bouzid and Moulay Abdellah sites, conversely, in Saada and Jorf Lasfar sites the highest values were observed in February and Mars respectively. The thallus length was slightly larger in Moulay Abdellah site with 77,30 ± 14.09 cm in compare with the three other sites during summer/spring periods. Minimum thalli length was recorded in September for all studied sites. The thalli of S. muticum were fertile earlier in Sidi Bouzid and Saada during spring and peaks during summer season for all studied sites showing a positive correlation with increasing temperature. Finally, the collected data shows that indeed physicochemical parameters influence the bioecological parameters. Thus, contributed to a better understanding of the temporal variation of S. muticum phenology in Moroccan Atlantic coast, these data provide the necessary information for coastal marine management and biomonitoring program as well as sustainable utilization of this renewable marine resource.
Vertebral monstrosities: Phenotypically shortened fish with deformed vertebrae in endemic fish genus Hypselobarbus (Bleeker 1860), (Teleostei: Cyprinidae) from Western Ghats, India
Authors: M. Jeevan T. , Devadas Dayal , Ramteke Karan Kumar , Jaiswar A. K. 
Published: August 2023

Abstract

The vertebral deformity in four fish species of genus Hypselobarbus (Bleeker 1860), collected from three different river systems of the Western Ghats, biodiversity hotspot of India, are reported here. The radiographic images revealed reduced intra-vertebral space in comparison with the normal vertebrae. The phenotypic deformities have led to the deepening of the body with a more robust and reduced length. The deformed vertebrae were between 25 and 32. Slight genetic divergence of 1.1% between normal and deformed specimens in Mitochondrial cytochrome oxidase subunit 1 gene of Hypselobarbus lithopidos and H. thomassi and no divergence in H. dobsoniand H. jerdoni was observed. Several environmental and genetic factors might have influenced the development of these robust short-bodied phenotypes in these rivers and possess slight genetic divergence from normal specimens. The specimens were collected from areas with high anthropogenic stresses, abate water quality, and habitat, which could also be a possible reason. However, these deformities may also be the result of the stress during embryonic and early life stages.