bluuebunny/crossref_metadata_2025_split huggingface dataset:
A prospective multicentre study evaluating the outcomes of the abdominal wall dehiscence repair using posterior component separation with transversus abdominis muscle release reinforced by a retro-muscular mesh: filling a step
Authors: Habeeb Tamer A. A. M. , Hussain Abdulzahra , Shelat Vishal , Chiaretti Massimo , Bueno-Lledó Jose , García Fadrique Alfonso , Kalmoush Abd-Elfattah , Elnemr Mohamed , Safwat Khaled , Raafat Ahmed , Wasefy Tamer , Heggy Ibrahim A. , Osman Gamal , Abdelhady Waleed A. , Mawla Walid A. , Fiad Alaa A. , Elaidy Mostafa M. , Amr Wessam , Abdelhamid Mohamed I. , Abdou Ahmed Mahmoud , Ibrahim Abdelaziz I. A. , Baghdadi Muhammad Ali 
Published: March 2023

Abstract
Background
This study aimed to evaluate the results of posterior component separation (CS) and transversus abdominis muscle release (TAR) with retro-muscular mesh reinforcement in patients with primary abdominal wall dehiscence (AWD). The secondary aims were to detect the incidence of postoperative surgical site occurrence and risk factors of incisional hernia (IH) development following AWD repair with posterior CS with TAR reinforced by retromuscular mesh.

Methods
Between June 2014 and April 2018, 202 patients with grade IA primary AWD (Björck's first classification) following midline laparotomies were treated using posterior CS with TAR release reinforced by a retro-muscular mesh in a prospective multicenter cohort study.

Results
The mean age was 42 ± 10 years, with female predominance (59.9%). The mean time from index surgery (midline laparotomy) to primary AWD was 7 ± 3 days. The mean vertical length of primary AWD was 16 ± 2 cm. The median time from primary AWD occurrence to posterior CS + TAR surgery was 3 ± 1 days. The mean operative time of posterior CS + TAR was 95 ± 12 min. No recurrent AWD occurred. Surgical site infections (SSI), seroma, hematoma, IH, and infected mesh occurred in 7.9%, 12.4%, 2%, 8.9%, and 3%, respectively. Mortality was reported in 2.5%. Old age, male gender, smoking, albumin level < 3.5 gm%, time from AWD to posterior CS + TAR surgery, SSI, ileus, and infected mesh were significantly higher in IH. IH rate was 0.5% and 8.9% at two and three years, respectively. In multivariate logistic regression analyses, the predictors of IH were time from AWD till posterior CS + TAR surgical intervention, ileus, SSI, and infected mesh.

Conclusion
Posterior CS with TAR reinforced by retro-muscular mesh insertion resulted in no AWD recurrence, low IH rates, and low mortality of 2.5%.
Trial registration Clinical trial: NCT05278117.
Local torsion of distal femur is a risk factor for patellar dislocation
Authors: Fan Chongyi , Niu Yingzhen , Wang Fei 
Published: March 2023

Abstract
Purpose
It has been widely reported that femoral anteversion is a risk factor for patellar dislocation. This study aims to evaluate whether internal torsion of the distal femur is noticeable in patients without increased femoral anteversion and to assess whether it is a risk factor for patellar dislocation.

Methods
A retrospective analysis was conducted on 35 patients (24 females, 11 males) with recurrent patellar dislocation but without increased femoral anteversion treated in our hospital from January 2019 to August 2020. All patients underwent knee X-rays, digital radiography of lower-limbs, and CT scans of hip, knee, and ankle joints to measure femoral anteversion angle, distal femoral torsion angle, TT–TG and Caton-Deschamps index. Thirty-five control cases were matched on age and sex to compare the difference of anatomic parameters between the two groups, and the logistic analysis was used to analyze risk factors for patellar dislocation. Perman correlation coefficient was used to evaluate the correlation among femoral anteversion, distal femoral torsion and TT–TG.

Results
Greater distal femoral torsion was still observed in patients with patellar dislocation but without increased femoral anteversion. The torsion angle of distal femur, TT–TG distance and incidence of Patella Alta in patients with patellar dislocation were greater than those in control group, and the inter-group differences were statistically significant (P < 0.05). The torsion angle of distal femur (OR = 2.848, P < 0.001), TT–TG distance (OR = 1.163, P = 0.021) and Patella Alta (OR = 3.545, P = 0.034) were risk factors for patellar dislocation. However, no significant correlation was found among femoral anteversion, distal femoral torsion and TT–TG in patients with patellar dislocation.

Conclusion
On the condition that femoral anteversion did not increase, increased distal femoral torsion was commonly observed in patients with patellar dislocation, which represents an independent risk factor for patellar dislocation.
The live birth rate of vitrified oocyte accumulation for managing diminished ovarian reserve: a retrospective cohort study
Authors: Lee Kuan-Sheng , Lin Ming-Huei , Hwu Yuh-Ming , Yang Jia-Hwa , Lee Robert Kuo-Kuang 
Published: March 2023

Abstract
Background
Vitrified M-II oocyte accumulation for later simultaneous insemination has been used for managing POR. Our study aimed to determine whether vitrified oocyte accumulation strategy improves live birth rate (LBR) for managing diminished ovarian reserve (DOR).

Methods
A retrospective study included 440 women with DOR fulfilling Poseidon classification groups 3 and 4, defined as the presence of serum anti-Müllerian hormone (AMH) hormone level < 1.2 ng/ml or antral follicle count (AFC) < 5, from January 1, 2014, to December 31, 2019, in a single department. Patients underwent accumulation of vitrified oocytes (DOR-Accu) and embryo transfer (ET) or controlled ovarian stimulation (COS) using fresh oocytes (DOR-fresh) and ET. Primary outcomes were LBR per ET and cumulative LBR (CLBR) per intention to treat (ITT). Secondary outcomes were clinical pregnancy rate (CPR) and miscarriage rate (MR).

Results
Two hundred eleven patients underwent simultaneous insemination of vitrified oocyte accumulation and ET in the DOR-Accu group (maternal age: 39.29 ± 4.23 y, AMH: 0.54 ± 0.35 ng/ml), and 229 patients underwent COS and ET in the DOR-fresh group (maternal age: 38.07 ± 3.77 y, AMH: 0.72 ± 0.32 ng/ml). CPR in the DOR-Accu group was similar in the DOR-fresh group (27.5% vs. 31.0%, p = 0.418). However, MR was statistically higher (41.4% vs. 14.1%, p = 0.001), while LBR per ET was statistically lower (15.2% vs. 26.2%, p < 0.001) in the DOR-Accu group. There is no difference in CLBR per ITT between groups (20.4% vs. 27.5%, p = 0.081). The secondary analysis categorized clinical outcomes into four groups regarding patients’ age. CPR, LBR per ET, and CLBR did not improve in the DOR-Accu group. In the group of 31 patients, accumulated vitrified metaphase II (M-II) oocytes reached a total number of ≥ 15, and CPR improved among the DOR-Accu group (48.4% vs. 31.0%, p = 0.054); however, higher MR (40.0% vs. 14.1%, p = 0.03) resulted in similar LBR per ET (29.0% vs. 26.2%, p = 0.738).

Conclusions
Vitrified oocyte accumulation for managing DOR did not improve LBR. Higher MR resulted in lower LBR in the DOR-Accu group. Therefore, the vitrified oocyte accumulation strategy for managing DOR is not clinically practical.

Trial registration
The study protocol was retrospectively registered and was approved by Institutional Review Board of Mackay Memorial Hospital (21MMHIS219e) on August 26, 2021.
A big data study of language use and impact in radio broadcasting in China
Authors: Zhang Ruihua , Zhou Jincheng , Hai Tao , Zhang Shixue , Iwendi Marvellous , Shah Mohd Asif , Osamor Jude 
Published: March 2023

Abstract
Broadcasting more educating and language-reviving contents are ways radio stations can help revitalize the use of the English language in the Hunan province of China. The challenges faced in communicating in English in Chinese radio stations are majorly caused by the lack of language professionals and linguists in the broadcast stations. The absence of these professionals is a major constraint to the development of the community. The broadcast media can help manage multilingualism through the introduction of new words which would give little or no room for lexicon dearth but would expand the language lexicon. Using the English language during broadcast reduces language dearth, and helps reach a much larger audience, even those not in China. Programmes anchored in English in places where the language is barely spoken enhances the vocabulary, comprehension and language vitality of the listeners. This study examined the impact of the English language used in radio broadcasting using a descriptive Big Data survey research design. The study’s population comprises of the inhabitants of the Hunan province in China, from which a sample of 50 broadcast staff and 150 regular inhabitants was drawn using a stratified random sampling technique. The instrument of data collection was a structured questionnaire with closed questions and a self-structured interview. The sample employed frequency distribution tables, percentages, and charts in the presentation and analysis of data. The results revealed that majority of the respondents in Hunan listened to radio broadcast indicating that the use of English language can have massive impact on the people. The study also found that majority of the respondents use their indigenous languages in their day-to-day activities as well as their schools with English being used majorly only in schools with only English-speaking students. The study recommends, amongst others, that the Broadcasting Corporation of China (BCC) review their policy on the allocated time of broadcast in English languages, and that more English language experts and linguists should be incorporated into the broadcast system.
Impact of the COVID-19 pandemic on the mental health and social functioning of healthcare workers
Authors: Belcarz Maria , Marczewska Sylwia 
Published: March 2023

Introduction: The work of medical staff (doctors, nurses) is very stressful, especially during a pandemic. They often bear a lot of responsibility, work under time pressure and take care of a terminally ill patient. This unique time affects not only medical workers but also their families. The rules of functioning in a group and society are changing, and the possibility of exposure to infection by colleagues, relatives or friends is a risk factor for mental health problems.
The aim of the study: The aim of the study was to analyse the prevalence of mental disorders and changes in the social functioning of medical workers during the Covid-19 pandemic.
Materials and methods: Survey search using author-made questionnaire was conducted. The study group consisted of people from 22 to 66 years of age. The survey was anonymous. The study material was analyzed, consisting of 127 correctly completed questionnaires. Collected data was then transformed for statistical purposes and the correlations were examined using Mann-Whitney U test (men vs women).
Results: Comparing the situation before the pandemic to the present one statistically significant increase in to experience stress at work for women. Nearly 90% of surveyed individuals are afraid of being infected with SARS-CoV-2 virus by a patient. Medical personnel (nurses, paramedics, doctors) are experiences stress (83%), fear (65%) and anxiety (76%) in the workplace. 10% of respondents took advantage of the psychological support.
Conclusions: The mental condition and functioning in the society of medical workers is significantly impaired due to the ongoing Covid-19 pandemic. Medical workers are exposed to constant stress, anxiety, powerlessness and their social activity is disturbed.
Managing chronic kidney disease, diabetes and coronary artery disease
Authors: Ellis Peter 
Published: March 2023

Chronic kidney disease, diabetes and coronary artery disease frequently co-exist in the same patient. The management of this triad of diseases is complex and requires a working knowledge of the management of each individual disease. This article identifies the main strategies for managing all three diseases in general practice and the role of the general practice nurse in this. Chronic kidney disease, type 2 diabetes and coronary artery disease frequently co-exist in the same patient. Peter Ellis describes the role of the general practice nurse in supporting patients with these conditions
SURGICAL MANAGEMENT OF LUMBAR STENOSIS IN THE PRESENCE OF DEGENERATIVE SPONDYLOLISTHESIS: ARE DECOMPRESSION AND FUSION OR INTERSPINOUS PROCESS DEVICE SUPERIOR TO DECOMPRESSION ALONE? A SYSTEMATIC REVIEW AND META-ANALYSIS
Authors: Glendenning A.C. , Richards T. , Singh S. , Khurana A. 
Published: March 2023

AimsTo compare the efficacy of decompression alone (DA) with i) decompression and fusion (DF) and ii) interspinous process device (IPD) in the treatment of lumbar stenosis with degenerative spondylolisthesis. Outcomes of interest were both patient-reported measures of postoperative pain and function, as well as the perioperative measures of blood loss, operation duration, hospital stay, and reoperation.MethodsData were obtained from electronic searches of five online databases. Included studies were limited to randomised-controlled trials (RCTs) which compared DA with DF or IPD using patient-reported outcomes such as the Oswestry Disability Index (ODI) and Zurich Claudication Questionnaire (ZCQ), or perioperative data.Patient-reported data were reported as part of the systematic review, while meta-analyses were conducted for perioperative outcomes in MATLAB using the DerSimonian and Laird random-effects model. Forest plots were generated for visual interpretation, while heterogeneity was assessed using the I2-statistic.ResultsA total of 13 articles met the eligibility criteria. Of these, eight compared DA with DF and six studies compared DA with IPD. Patient-rated outcomes reported included the ODI and ZCQ, with mixed results for both types of comparisons. Overall, there were few statistically significant and no clinically significant differences in patient-rated outcomes. Study quality varied greatly across the included articles.Meta-analysis of perioperative outcomes revealed DF to result in greater blood loss than DA (MD = 406.74 ml); longer operation duration (MD = 108.91 min); and longer postoperative stay in hospital (MD = 2.84 days). Use of IPD in comparison to DA led to slightly reduced operation times (MD = –25.18 min), but a greater risk of reoperation compared to DA (RR = 2.70).ConclusionCurrently there is no evidence for the use of DF or IPD over DA in both patient-rated and perioperative outcomes. Indeed, both procedures can potentially lead to greater cost and risk of complications, and therefore, a stronger evidence base for their use should be established before they are promoted as routine options in patients with degenerative spondylolisthesis.
Development and validation of a pharmaceutical assessment screening tool to prioritise patient care in a tertiary care hospital
Authors: Chang Cheok Ee , Khan Rahela Ambaras , Tay Chan Yen , Thangaiyah Baavaanii , Ong Victor Sheng Teck , Pakeer Oothuman Sabariah , Zulkifli Shazwani , Azemi Nur Fatin Najwa , Subramaniam Pavithira 
Published: March 2023

BackgroundClinical pharmacy plays an integral role in optimizing inpatient care. Nevertheless, prioritising patient care remains a critical challenge for pharmacists in a hectic medical ward. In Malaysia, clinical pharmacy practice has a paucity of standardized tools to prioritise patient care.AimOur aim is to develop and validate a pharmaceutical assessment screening tool (PAST) to guide medical ward pharmacists in our local hospitals to effectively prioritise patient care.MethodThis study involved 2 major phases; (1) development of PAST through literature review and group discussion, (2) validation of PAST using a three-round Delphi survey. Twenty-four experts were invited by email to participate in the Delphi survey. In each round, experts were required to rate the relevance and completeness of PAST criteria and were given chance for open feedback. The 75% consensus benchmark was set and criteria with achieved consensus were retained in PAST. Experts’ suggestions were considered and added into PAST for rating. After each round, experts were provided with anonymised feedback and results from the previous round.ResultsThree Delphi rounds resulted in the final tool (rearranged as mnemonic ‘STORIMAP’). STORIMAP consists of 8 main criteria with 29 subcomponents. Marks are allocated for each criteria in STORIMAP which can be combined to a total of 15 marks. Patient acuity level is determined based on the final score and clerking priority is assigned accordingly.ConclusionSTORIMAP potentially serves as a useful tool to guide medical ward pharmacists to prioritise patients effectively, hence establishing acuity-based pharmaceutical care.
Assessing the association between an early and recommended number of focused antenatal care visits and the number of prenatal care content received before delivery in Ethiopia
Authors: Kpordoxah Mary Rachael , Issah Abdul-Nasir , Yeboah Daudi , Mruts Kalayu Brhane , Boah Michael 
Published: March 2023

Background
Early and frequent antenatal care (ANC) has been linked to better pregnancy outcomes. This study assessed whether having at least four ANC contacts was associated with increased prenatal care content if the first visit was started in the first trimester in Ethiopia.

Methods
Data from the 2019 Ethiopia Mini Demographic and Health Survey on 2894 women aged 15–49 who received ANC during their last pregnancy were analyzed. The sum of women’s responses to six questions about ANC components (blood pressure taken, urine sample taken, blood sample taken, provided or bought iron tablet, counselling by a health worker on nutrition, and told about pregnancy complications) was used to construct a composite score of routine ANC components. The main predictor was a combination of the timing of the first contact and the number of ANC contacts before birth.

Results
We found that 28.7% of women who began ANC early made at least four ANC contacts. More than one-third (36%) received all six components, with blood pressure monitoring being the most common (90.4%). After adjusting for potential confounding factors, women who had at least four contacts and booked early were substantially more likely than their counterparts to get a factor-of-one increase in the number of components received (IRR = 1.08; 95% CI: 1.03, 1.10).

Conclusion
We found a strong association between increased prenatal care content and early ANC with at least four contacts. However, less than a third of women in the study setting had at least four contacts, with the first occurring in the first trimester. In addition, less than half of women received essential prenatal care interventions before delivery. The findings suggest that the WHO’s new guidelines for ANC frequency and timing may be challenging to implement in some countries, such as Ethiopia, that already have low coverage of four or more contacts. If the recommendations are adopted, effective strategies for increasing early starts and increasing contacts are required.
An Enigmatic Case of Jaundice and Photosensitivity in an Adolescent
Authors: Bhagat Naveen , Singh Pranjal , De Arka , Mitra Suvradeep , Kumar Ashwani , Dhanasekaran Venkatesh , Parkhi Mayur Vilas , Ray Debadrita , Duseja Ajay 
Published: March 2023

ABSTRACT
Erythropoietic protoporphyria (EPP) presents with nonblistering photosensitivity. Hepatobiliary manifestations are seen in around 5% cases and include cholelithiasis, elevations in liver enzymes, progressive jaundice, and end-stage liver disease. The diagnosis is suspected based on clinical features and elevated erythrocyte metal-free protoporphyrin and confirmed by genetic analysis showing loss-of-function mutations in the ferrochelatase (FECH) gene. We present an adolescent boy who presented with jaundice and photosensitivity with the liver biopsy showing deposition of brown pigments within the canaliculi and hepatocytes. This pigment showed Maltese cross birefringence on polarizing microscopy and Medusa-head appearance on electron microscopy. Genetic analysis revealed loss-of-function mutations in FECH. Introduction of EPP is an inborn error of heme biosynthesis caused by mutations in FECH with a prevalence of 1:75,000 to 1:200,000. We present a case of a 16-year-old adolescent boy with photosensitivity, abdominal pain, and jaundice with protoporphyrin deposition in the liver who was ultimately diagnosed with EPP based on genetic analysis.
Impacto de la pandemia de COVID-19 sobre la utilización de la medición de la HbA1c y sus resultados en pacientes ambulatorios adultos y pediátricos con diabetes
Authors: Oliver Paloma , Pellicer Marina , Prieto Daniel , Diaz-Garzon Jorge , Mora Roberto , Tomoiu Ileana , Gonzalez Noemi , Carcavilla Atilano , Gonzalez-Casado Isabel , Losantos Itsaso , Buño Antonio , Pilar Fernandez-Calle  
Published: March 2023

Resumen

Objetivos
La diabetes mellitus incrementa los riesgos y complicaciones asociadas a la COVID-19. Una de las principales consecuencias de la pandemia ha sido la drástica reducción de las consultas presenciales. El objetivo de este estudio es evaluar el impacto que ha tenido la pandemia de COVID-19 en la gestión de la determinación de HbA1c y sus resultados en pacientes ambulatorios adultos y pediátricos con diabetes, teniendo en cuenta tanto la medición realizada en el laboratorio como las pruebas de laboratorio en el lugar de asistencia o point-of-care testing (POCT).

Métodos
Se realizó un estudio observacional retrospectivo que incluyó pacientes de las Unidades de Diabetes Pediátrica y de Adultos. A través del sistema de información del laboratorio, se extrajeron los resultados de HbA1c obtenidos en el laboratorio y los resultados de POCT en un periodo de tres años (2019–2021).

Resultados
El número de mediciones de HbA1c se redujo considerablemente tras el confinamiento. En poco tiempo, los pacientes pediátricos volvieron a recibir su asistencia médica habitual. El número de mediciones de HbA1c fue aumentando paulatinamente en los adultos, especialmente POCT. En general, los valores de HbA1c fueron inferiores en los pacientes pediátricos que en los adultos (p<0,001). Los valores de HbA1c en niños (p<0,001) y adultos (p=0,002) se redujeron tras la pandemia con respecto al periodo previo a la misma, aunque fueron inferiores al valor de referencia del cambio de la HbA1c. El porcentaje de resultados de HbA1c superiores al 8% se mantuvo estable durante el periodo de estudio.

Conclusiones
Los sistemas de monitorización continua de la glucosa y la telemedicina fueron cruciales, habiéndose producido incluso una mejoría respecto a los niveles de HbA1c. Durante el confinamiento, a los pacientes con mejor control metabólico, las pruebas analíticas se les realizaron en el laboratorio, mientras que a los pacientes con peor control o una situación clínica grave se les realizaron mediante POCT en las Unidades de Diabetes. En los pacientes adultos, el retorno a la asistencia habitual previa a la pandemia se produjo de forma lenta y gradual, ya que presentaban mayor riesgo de morbimortalidad asociado a la COVID-19. La coordinación entre todos los profesionales sanitarios fue esencial a la hora de garantizar la mejor atención posible, especialmente en escenarios complejos, como la pandemia de COVID-19.