bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical spectrum of Chinese hospitalized lung cancer patients with concomitant interstitial lung disease: before and after the new era of LC treatment
Authors: Chen Ruxuan , Shao Chi , Liu Xiangning , Huang Hui , Pan Boju , Xu Kai , Zhu Rui , Li Mei , Zhao Yang , Chen Keqi , Wang Mengzhao , Xu Zuojun 
Published: January 2023

AbstractThis study aimed to explore the general characteristics and spectrum of hospitalized Chinese patients suffering from lung cancer with concomitant interstitial lung disease (LC-ILD). Furthermore, we compared their features before and after the period of immunotherapy for lung cancer. A retrospective analysis of the clinical characteristics of hospitalized LC patients with definite pathological diagnoses was performed from 2014 to 2021. ILD was defined after the review of chest CT imaging. There were 13,085 hospitalized LC patients. Among them, 509 patients (3.89%) had 551 cases of ILD. There were variable underlying causes of ILD, including idiopathic interstitial pneumonia (360 patients), LC treatment-associated ILD (134 cases), and connective tissue disease-associated ILD (55 patients). Although most LC-ILD patients were suffering from adenocarcinoma (204/40.1%), SCLC patients were prone to concomitant ILD (10.8% of all SCLC cases), followed by SCC (9.6% of all SCC cases). All but 10 LC-ILD patients received anti-LC treatment; however, only 39 (10.8%) LC-IIP patients received anti-ILD treatment. There were more LC-ILD patients in the 2018–2021 group than in the 2014–2017 group (5.16% vs. 2.03%, p < 0.001). The underlying causes of ILD were significantly different between the 2018–2021 group and the 2014–2017 group (p < 0.001). After adjusting for the number of hospitalized patients having the same LC pathological pattern, SCLC was determined to be the most likely to be concomitant with ILD, followed by SCC. Most LC-ILD patients were scheduled for anti-LC therapy; however, treatments for concomitant IIP were usually ignored. LC treatment-associated ILD should receive more attention than before.
A novel pump-free ultrafiltration rate modulation system for continuous renal replacement therapy applications
Authors: Ventresca Alessandra , Comai Guido , Severi Stefano 
Published: January 2023

Abstract
Purpose
Extracorporeal ultrafiltration is an attractive alternative to diuretics for removing excess plasma water in critically ill patients suffering from fluid overload. In continuous renal replacement therapy (CRRT), ultrafiltration occurs in isolated form (SCUF) or supplemented by replacement fluid infusion (CVVH) and the net fluid removal rate is controlled by peristaltic pumps. In this work, a pump-free solution for regulating the ultrafiltration rate in CRRT applications is presented.

Methods
The system consists of a motorized clamp on the ultrafiltration line, whose intermittent opening is modulated with a closed-loop control system based on monitoring of ultrafiltrate collected and any replacement fluid infused. The system was tested on two platforms for SCUF and CVVH, with “low-flux” and “high-flux” hemofilter, with various ultrafiltration setpoints and patient net weight loss targets.

Results
In all configurations the set ultrafiltration rate was achieved with a maximum error of 5% and the values recorded were kept within ± 100 ml/h with respect to the setpoint, as recommended by international standard IEC 60601-2-16. The net fluid removal trend was highly correlated with that expected (95%<R2<99%) and the weight loss target was reached in the expected time. For low ultrafiltration rates (60-150 ml/h) the system accuracy was better with the “low-flux” hemofilter.

Conclusion
The developed clamp system represents a valid alternative to state-of-the-art solutions with peristaltic pumps in terms of performance, with potential usability advantages. The compliance with safety requirements given by international standard IEC 60601-2-16 is a prerequisite for clinical use.
Experimental investigation of the acoustic emission of an electrically driven propeller in thrust and recuperation mode in a wind tunnel
Authors: Hille Sebastian , Meyers Philippe , Mayntz Joscha , Dahmann Peter , Stumpf Eike 
Published: January 2023

AbstractThis paper presents the results of an experimental performance study of an electrically driven propeller in thrust and power recuperation mode in a subsonic wind tunnel. Using the reverberation chamber method, acoustic measurements were performed to evaluate them as a reference in relation to the performance data obtained. The three approaches to recuperation were investigated: Fixed pitch propeller at speed reduction (case 1), controllable pitch propeller with negative angle of attack (case 2), and inverted, backward running propeller (case 3). Results show that in-flight recuperation can be optimized in terms of low noise emissions and generating shaft power from the flow efficiently by choosing the respective operating point. For the latter, case 3 shows the greatest potential for a two bladed propeller, while case 2 has the lowest noise emissions and might reach higher values in recuperated power by increasing the propeller blade number.
Bi-directional Scan Pattern Effects on Residual Stresses and Distortion in As-built Nitinol Parts: A Trend Analysis Simulation Study
Authors: Monu Medad C. C. , Afkham Yalda , Chekotu Josiah C. , Ekoi Emmanuel J. , Gu Hengfeng , Teng Chong , Ginn Jon , Gaughran Jennifer , Brabazon Dermot 
Published: January 2023

AbstractIn this paper, a part-scale simulation study on the effects of bi-directional scanning patterns (BDSP) on residual stress and distortion formation in additively manufactured Nitinol (NiTi) parts is presented. The additive manufacturing technique of focus is powder bed fusion using a laser beam (PBF-LB), and simulation was performed using Ansys Additive Print software. The numerical approach adopted in the simulation was based on the isotropic inherent strain model, due to prohibitive material property requirements and computational limitations of full-fledged part-scale 3D thermomechanical finite element approaches. In this work, reconstructed 2D and 3D thermograms (heat maps) from in situ melt pool thermal radiation data, the predicted residual stresses, and distortions from the simulation study were correlated for PBF-LB processed NiTi samples using selected BDSPs. The distortion and residual stress distribution were found to vary greatly between BDSPs with no laser scan vector rotations per new layer, whereas negligible variations were observed for BDSPs with laser scan vector rotations per new layer. The striking similarities between the reconstructed thermograms of the first few layers and the simulated stress contours of the first lumped layer provide a practical understanding of the temperature gradient mechanism of residual stress formation in PBF-LB processed NiTi. This study provides a qualitative, yet practical insight towards understanding the trends of formation and evolution of residual stress and distortion, due to scanning patterns.
Recognition of Children’s Learning in Educational Research, Policy and Practice: Herbison Invited Lecture, NZARE Annual Conference 2022
Authors: O’Neill John 
Published: January 2023

AbstractFor Jean Herbison, learning in her early 20th century childhood world was relatively uncomplicated and predictable. Life was shaped by unambiguous family, faith and settler colonial prescriptions about how children should behave and what they should become. Approaching the centenary of her birth, children today must navigate a very different society of ‘unlimited can’; an achievement society that generates a debilitating compulsion to self-improve (Byung Chul-Han).In this Herbison lecture, I offer a personal reflection on the contemporary ‘triangle’ of education research, policy and practice in Aotearoa New Zealand. Viewed as a culturally and historically specific ‘form of life’ (Rahel Jaeggi), I ask whether, over the last thirty five years, this triangle may have unwittingly contributed to a collective failure to give adequate recognition to children’s learning. Despite our best intentions, have we simply reified students and in doing so alienated them from learning in all its complexities and dimensions (Knud Illeris)?More than mere acknowledgement of ‘the other’, recognition theory highlights the importance of socially developed qualities such as confidence, respect and esteem (Axel Honneth) to each child’s capacity to develop meaningful relationships to or ‘resonance’ with an ever accelerating and uncontrollable world (Hartmut Rosa) and the people and communities in it. In practical terms, then, what can we draw on that is already immanent in our research, policy and practice triangle to transform children’s institutionalised learning?
Trust, Brutality, and Human Dignity: How “Partial Birth Abortion” Helps Shape American Biopolitics
Authors: Annas George J. 
Published: January 2023

AbstractIn this Article, I explore how nearly continuous public rhetorical challenges to abortion in the political realm first led the public and the courts to turn away from a particular abortion procedure (intact dilation and extraction, also known as partial-birth abortion) which political agitators labeled as “barbaric” and then to view physicians who performed abortions not as legitimate professionals, but simply as “abortionists,” and sometimes as evil “Frankensteins.” “Abortionists” use no “medical judgment” and are unworthy of deference by state legislatures, Congress, or the courts when deciding how or when to perform an abortion. The concentration on the welfare of fetuses and the actions of physicians permitted the abortion debate to bypass discussion of both the rights and welfare of pregnant patients, including their right to health, and to virtually never mention that abortion restrictions primarily affect people in poverty who cannot afford to seek reproductive health care, including an abortion, by traveling to a nonrestrictive state. Understanding the power of extreme rhetoric, including the use of social media in political campaigns and the use and misuse of concrete terms such as murder, infanticide, brutality, and dismemberment, and abstract concepts such as “human dignity,” can help us plot a post-Dobbs way forward. Perhaps the demise of Roe can lead to a birth of a new rhetoric on abortion, one that concentrates on the right to health of everyone, including the right to make reproductive decisions, and requires moving abortion back into the realm of contemporary medicine, complete with a meaningful doctor-patient relationship protected by privacy and financed in a way that is accessible to all pregnant patients.
Pregnant Women and Opioid Use Disorder: Examining the Legal Landscape for Controlling Women’s Reproductive Health
Authors: Madden Lynn M. , Oliva Jenn , Eller Anthony , DiDomizio Elizabeth , Roosa Mat , Blanchard Lisa , Kil Natalie , Altice Frederick L. , Johnson Kimberly 
Published: January 2023

AbstractWomen with opioid use disorder (“OUD”) are more likely than other women to experience sexual assault, unintentional pregnancy, transactional sex and coercion regarding reproductive health care choices than women without OUD. Laws described as family friendly may be punitive rather than helpful to women and rarely apply to men. Laws regarding reproductive health and OUD are unevenly enforced and therefore biased against poor, minority women. As part of a larger study oriented toward strengthening systems of care related to the intersection of HIV and OUD, we conducted an analysis of state laws related to pregnant and postpartum women with OUD. Data on disparities in child removals and pregnant women’s use of evidence-based treatment for OUD by income and race were captured for the five states with the most restrictive laws in both categories. Laws that were purportedly designed to improve reproductive health outcomes for women with OUD and/or their children often have the opposite of the expressed intended outcome. There is a relationship between restrictive reproductive choice and coercive OUD treatment policy for women. Restrictive state regulations for pregnant women with OUD persist despite negative outcomes for maternal and child health. Altering coercive and/or criminalizing regulation and redefining ‘family friendly’ may improve outcomes for individuals and families.
Impact of the COVID-19 Pandemic on Stroke Subtype Presentation in Patients Without COVID-19 Infection
Authors: Sawicka Katherine M. , Catanese Luciana , Williams Janice , Crellin Lisa , Francis Troy , Katsanos Aristeidis H. , Shoamanesh Ashkan , Chen Jennifer , Pikula Aleksandra , Schaafsma Joanna D. 
Published: January 2023

ABSTRACT:Background & Aims:It is unknown if the COVID-19 pandemic and public health measures had an immediate impact on stroke subtypes and etiologies in patients not infected with COVID-19. We aimed to evaluate if the proportion of non-COVID-19-related stroke subtypes (ischemic vs. hemorrhagic) and etiologies (cardioembolic, atherosclerosis, small vessel disease, and others) during the pandemic’s first wave were different from prepandemic.Methods:For this retrospective cohort study, we included patients without COVID-19 with ischemic or hemorrhagic stroke at two large Canadian stroke centers between March–May 2019 (prepandemic cohort) and March–May 2020 (pandemic cohort). Proportions of stroke subtypes and etiologies were compared between cohorts using chi-square tests.Results:The prepandemic cohort consisted of 234 stroke patients and the pandemic cohort of 207 stroke patients. There were no major differences in baseline characteristics. The proportions of ischemic versus hemorrhagic stroke were similar (ischemic stroke: 77% prepandemic vs. 75% pandemic; hemorrhagic stroke:12% prepandemic vs. 14% pandemic; p > 0.05). There were no differences in etiologies, except for a decreased proportion of ischemic stroke due to atherosclerosis in the pandemic cohort (26% prepandemic vs. 15% pandemic; difference: 10.6%, 95%CI: 1.4-19.7; p = 0.03). Notably, during the pandemic, the cause of ischemic stroke was more often unknown because of incomplete work-up (13.3% prepandemic vs. 28.2% pandemic, difference: 14.9%, 95%-CI: 5.7–24.2; p = <0.01).Conclusions:In this study, the pandemic had no clear effect on stroke subtypes and etiologies suggesting a limited impact of the pandemic on stroke triggers. However, the shift from atherosclerosis toward other causes warrants further exploration.
Antimicrobial use and opportunities for antimicrobial stewardship in pediatric postacute and long-term care settings
Authors: Johnson Candace L. , Neu Natalie , Saiman Lisa 
Published: January 2023

AbstractWe performed a point-prevalence study of antimicrobial prescriptions in 9 pediatric postacute and long-term care (pPALTC) settings. Antimicrobials were prescribed for 5%–7% of residents including infectious (41%), noninfectious (24%), prophylaxis (24%), and unknown (11%) indications. Macrolides were often prescribed for noninfectious indications. Developing treatment guidelines are antimicrobial stewardship opportunities for pPALTC.
Nd–Sr–Pb isotopes systematics of the Jurassic Evros ophiolite, eastern Circum-Rhodope Belt, NE Greece
Authors: Bonev Nikolay , Dotseva Zornitsa , Chiaradia Massimo 
Published: January 2023

AbstractWe report on the isotopic compositions of the Jurassic supra-subduction zone Evros ophiolite mafic rocks exposed in the eastern Circum-Rhodope Belt of northeastern Greece. These mafic units consist of low-Ti gabbroic and basaltic rocks, whose Nd–Sr–Pb isotopes are compatible with dominant mantle-derived MORB component mixed with a detectable amount of crustal material and/or sediment invoved in their melt source in the subduction zone. These isotopic features are consistent with an intra-oceanic arc origin of the mafic ophiolite rocks, and the Evros ophiolite Nd and Pb isotopes are comparable to those of the counterpart mafic rocks from the Mandritsa unit in Bulgaria.
Terrorist Attacks in Sub-Saharan Africa from 1970 through 2020: Analysis and Impact from a Counter-Terrorism Medicine Perspective
Authors: Hata Ryan , Hart Alexander , Hertelendy Attila , Tin Derrick , Taubman Cara , Cheng Lenard , Ciottone Gregory R. 
Published: January 2023

AbstractBackground:Sub-Saharan Africa (SSA) has become a hotspot for global terrorism, with nearly 50% of global terror-related deaths occurring in SSA in 2021. With a large population and complex geopolitical and social climate, terrorist activity further burdens an already strained medical system. This study provides a retrospective descriptive analysis of terrorist-related activity in SSA from 1970-2020.Methods:A retrospective analysis of the Global Terrorism Database (GTD) was performed for the region of SSA from 1970-2020. Data were filtered using the internal database search function for all events in the following countries: Angola, Benin, Botswana, Burkina Faso, Burundi, Cameroon, Central African Republic, Chad, Comoros, the Democratic Republic of the Congo, Djibouti, Equatorial Guinea, Eritrea, Ethiopia, Gabon, Gambia, Ghana, Guinea, Guinea-Bissau, Ivory Coast, Kenya, Lesotho, Liberia, Madagascar, Malawi, Mali, Mauritania, Mozambique, Namibia, Niger, Nigeria, People’s Republic of the Congo, Republic of the Congo, Rhodesia, Rwanda, Senegal, Seychelles, Sierra Leone, Somalia, South Africa, South Sudan, Sudan, Swaziland, Tanzania, Togo, Uganda, Zaire, Zambia, and Zimbabwe. Number of attacks, deaths, and injuries, as well as primary weapons types, country where attacks occurred, and primary target types, were collated and analyzed.Results:A total 19,320 attacks were recorded, resulting in 77,565 deaths and 52,986 injuries. Firearms were the most frequent weapons used (8,745), followed by explosives (6,031), unknown (2,615), and incendiary (1,246), with all others making up the remainder (683.) Private citizens and property were the most frequently targeted entities (8,031), followed by general government facilities (2,582), police (1,854), business (1,446), military (805), diplomatic government facilities (741), and religious figures/institution (678), with all other targets making up the remainder (3,183).Conclusion:The majority of deaths from terrorism in SSA are the result of firearm attacks and explosions. Nigeria, Somalia, South Africa, The Democratic Republic of the Congo, and Sudan have had the largest number of attacks since 1970, and Nigeria has the largest number of people killed and injured. The health implications of terrorist attacks are often compounded by violence and pose unique challenges to governments, populations, and aid organizations. By understanding the impact and scope of terrorist activity in SSA, Counter-Terrorism Medicine (CTM) initiatives can be employed to improve health care outcomes.
Rethinking Multilingual Experience through a Systems Framework of Bilingualism: Response to Commentaries
Authors: Titone Debra A. , Tiv Mehrgol 
Published: January 2023

AbstractIn Rethinking Multilingual Experience through a Systems Framework of Bilingualism (Titone & Tiv, 2022), we encouraged psycholinguists and cognitive neuroscientists to consider integrating social and ecological aspects of multilingualism into a collective understanding of its cognitive and neurocognitive bases (i.e., to rethink experience). We then offered a framework – the Systems Framework of Bilingualism– and described empirical challenges and potential solutions with applying this framework to new research. Since the paper's publication, several eminent colleagues read and commented on our Keynote, noting both its strengths and areas for improvement. We read each commentary with enthusiasm and gratitude. Here, we briefly respond to several salient points raised, which led us to clarify and improve our theoretical approach. We first address what the commentaries agreed were strengths of the framework. We follow this with a discussion of what the commentaries stated could be improved or extended. We conclude with ways that we modified our model to collectively address concerns raised in the commentaries.
Understanding weight status and dietary intakes among Australian school children by remoteness: a cross-sectional study
Authors: Jacobs Jane , Strugnell Claudia , Becker Denise , Whelan Jill , Hayward Josh , Nichols Melanie , Brown Andrew , Brown Victoria , Allender Steven , Bell Colin , Sanigorski Andrew , Orellana Liliana , Alston Laura 
Published: January 2023

AbstractObjective:To determine whether primary school children’s weight status and dietary behaviours vary by remoteness as defined by the Australian Modified Monash Model (MMM).Design:A cross-sectional study design was used to conduct secondary analysis of baseline data from primary school students participating in a community-based childhood obesity trial. Logistic mixed models estimated associations between remoteness, measured weight status and self-reported dietary intake.Setting:Twelve regional and rural Local Government Areas in North-East Victoria, Australia.Participants:Data were collected from 2456 grade 4 (approximately 9–10 years) and grade 6 (approximately 11–12 years) students.Results:The final sample included students living in regional centres (17·4 %), large rural towns (25·6 %), medium rural towns (15·1 %) and small rural towns (41·9 %). Weight status did not vary by remoteness. Compared to children in regional centres, those in small rural towns were more likely to meet fruit consumption guidelines (OR: 1·75, 95 % CI (1·24, 2·47)) and had higher odds of consuming fewer takeaway meals (OR: 1·37, 95 % CI (1·08, 1·74)) and unhealthy snacks (OR = 1·58, 95 % CI (1·15, 2·16)).Conclusions:Living further from regional centres was associated with some healthier self-reported dietary behaviours. This study improves understanding of how dietary behaviours may differ across remoteness levels and highlights that public health initiatives may need to take into account heterogeneity across communities.
Globalizing the international: Bull's metaphysics of order
Authors: Burles Regan 
Published: January 2023

AbstractAs the origin story of the present world political order the globalization of international society serves as a unifying frame for the discipline of international relations. This paper considers the consequences of the shift from the ‘expansion’ to the ‘globalization’ of international society in relation to two main texts: Hedley Bull's The Anarchical Society and Tim Dunne and Christian Reus-Smit's The Globalization of International Society. The analysis shows that Bull's conception of world order depends on a key distinction between aggregate and system which marks the difference between an aggregate of local political orders and a systematically unified world political order (a global international system). Because recent histories of the globalization of international society remain guided by Bull's distinction, they are unable to explain this transition in historical terms without transforming the global international order from the explanandum of the globalization of international society to its explanans. As a result, global histories of the globalization of international society grant a global international system a structural permanence the original expansion story was meant to contest. In doing so they change profoundly the kind of questions that can be asked regarding the origins, character, and future of political order on earth.
Plato and Classical Civilisation A Level
Authors: Towey Alan 
Published: January 2023

AbstractThe incorporation of Plato into the current OCR Classical Civilisation A Level syllabus, as part of the Love and Relationships topic (LR) presents a challenge for the classroom teacher. While the specification makes study of Plato mandatory the content description in practice effectively relegates the topic to the side-lines. Having described this problem the article goes on to suggest how Plato's ideas can be taught within the framework of the existing specification in a pupil-friendly manner which is true to the spirit of Plato's own philosophical practice.