bluuebunny/crossref_metadata_2025_split huggingface dataset:
O consumo visto por diferentes perspectivas: uma análise das opiniões dos gestores de marketing, gestores de entidades de defesa do consumidor e consumidores
Authors: Bertuolo Claudemir , Minciotti Silvio Augusto 
Published: August 2023

O consumo comporta diversas discussões teóricas e posicionamentos quanto a liberdade e racionalidade do consumidor no consumo, bem como o seu poder frente às empresas. O artigo tem como objetivo conhecer o que pensam gestores de marketing, gestores de entidades de defesa do consumidor e consumidores sobre o consumo quanto à liberdade, razão e poder. Como metodologia fez-se uma pesquisa qualitativa na primeira etapa, com o uso de um roteiro de entrevistas semiestruturadas e da técnica de análise de conteúdo. A partir dos resultados da fase qualitativa, foi realizada uma pesquisa do tipo survey, com o uso de um formulário estruturado junto a consumidores da cidade de Goiânia/GO. Para a análise estatística utilizou-se o software “SPSS V 21”. Os resultados principais dão conta de que para os gerentes de marketing o consumidor é livre, age pela emoção no ato de consumo e é o ente mais forte na relação empresa-consumidor. Para os gestores de entidade defesa do consumidor, o consumidor não é livre, não pensa antes de comprar e é o mais fraco frente às empresas. Já os consumidores se dizem livres e racionais e reconhecem que há um equilíbrio de forças na relação com as empresas.
Analyzing the Trend, Change and Fluctuation in Area, Production and Productivity of Coriander in Different Districts of Chhattisgarh, India
Authors: Kabiraj Prakash , Rajak Suneel Kumar 
Published: August 2023

Coriander is first largest grown spice in the country during 2020-21 India accounting for 64.41 per cent (1430 thousand metric tones). The absolute change in area of coriander grown in Mahasamund district was found to be maximum (1.07 thousand hectare) and overall Chhattisgarh state have found 8.12 thousand hectare. Korba district was the highest relative change in area of coriander grown 398.92 per cent and overall Chhattisgarh state have 130.11 per cent. Mahasamund district had the greatest absolute change and relative change in coriander production (10.47 thousand tones and 44875.72%, respectively), Chhattisgarh state was found to be 46.66 thousand tones and 314.27 per cent, respectively. In Mahasamund district, the absolute and relative change in coriander productivity was found to be the greatest (8.72 thousand tones and 3128.38%) Chhattisgarh state was found 1.47 thousand tones and 57.53 per cent. The area and production was found to be minimum and more stable in Surguja district (17.80% and 41.48%) and overall Chhattisgarh state have found 37.36 and 57.12 per cent, respectively. The productivity was found to be minimum and more stable in Raighar district (25.46%) and more variable in Mahasamund (82.22%). Variability in productivity of overall Chhattisgarh state have found to be 25.83 per cent. Simple growth rate in area, production and productivity of coriander was found to be maximum in Mahasamund district (14.92, 21.12 and 14.70%) and overall Chhattisgarh state have found 5.50, 8.51 and 3.56 per cent, respectively. Trend in area of all coriander grown districts had shown positive and highly significant except Raigharh district. For the production of all coriander gown districts had show positive and highly significant except Rajnandgaon district.
Risk Assessment of Outdoor Gamma Radiation in Some Coastal Communities of Delta State, Nigeria
Authors: Furo Evelyn V. , Hart I. A. , Ononugbo Chinyere P. 
Published: August 2023

An assessment of background ionization radiation and associated health risk in some coastal communities of Delta State, Nigeria was carried out using a well calibrated portable radiation detector (Radalert-200) and GPS (Garmin GPS 72H) for the measurement of the geographical locations. The study covered Abiteye and Anotech Jetty water ways with nine notable communities assessed, where marine transportation and equipment haulage are predominant. The exposure rates ranged from 0.011 to 0.019 mRh−1 with overall mean value of 0.015 ± 0.002 mRh−1. The computed absorbed dose rates ranged from 95.70 to 165.30 nGyh-1 with overall mean value of 132.46 ± 19.05 nGyh-1. The estimated overall mean annual effective dose equivalent (AEDE) for the studied communities was 0.203±0.03 mSvy-1, while the overall mean excess lifetime cancer risk (ELCR) was (0.710±0.10) x10-3. The dose received by organs was highest in the testes (18%), the ovaries received 13%, while the liver had the lowest dose values (10%). Among all the estimated risk parameters, only the overall mean AEDE was found to be below the safe world recommended standard value while others were higher than their respective safe world average values. Hence the exposure may not constitute any immediate health risk to the resident of the study area.
Effect of a Nutrition Intervention on Mediterranean Diet Adherence Among Firefighters
Authors: Hershey Maria Soledad , Chang Chia-Rui , Sotos-Prieto Mercedes , Fernandez-Montero Alejandro , Cash Sean B. , Christophi Costas A. , Folta Sara C. , Muegge Carolyn , Kleinschmidt Vanessa , Moffatt Steven , Mozaffarian Dariush , Kales Stefanos N. 
Published: August 2023

ImportanceUS firefighters are a working population at risk of chronic diseases, including obesity, cardiovascular disease, and cancer. This risk may be mitigated by a healthy diet.ObjectiveTo evaluate the effect of a Mediterranean nutrition intervention using a behavioral/environmental approach (firefighter/fire station/home) at the individual participant level.Design, Setting, and ParticipantsThis 12-month cluster randomized clinical trial included US career firefighters from fire stations and homes within 2 Indiana fire departments. Participants were randomized by fire station to either Mediterranean diet or control (usual care). The study was conducted from October 2016 to December 2019, and data were analyzed in November 2022.InterventionFor the first 12 months of the study, firefighters located at fire stations randomized to the intervention group were provided with access to supermarket discounts and free samples of Mediterranean diet foods, online nutrition education platforms, email announcements and reminders, family and peer education and support, and chef demonstrations. Firefighters in fire stations allocated to the control group received no intervention and were instructed to follow their usual diet.Main Outcomes and MeasuresChange in dietary habits at 12 months as measured by a modified Mediterranean diet score (range, 0 to 51 points) at baseline and 6-month and 12-month follow-up. Cardiometabolic parameters were secondary outcomes.ResultsOf 485 included firefighters, 458 (94.4%) were male, and the mean (SD) age was 47 (7.5) years. A total of 241 firefighters (27 fire stations) were randomized to the Mediterranean nutrition intervention, and 244 (25 fire stations) were randomized to usual diet. Outcomes were analyzed using generalized linear mixed models for modified Mediterranean diet score at 6 months (n = 336) and 12 months (n = 260), adjusting for baseline age, sex, race and ethnicity, fire department, physical activity, and waist circumference. In the intervention group compared with the control group, the modified Mediterranean diet score significantly increased by 2.01 points (95% CI, 0.62-3.40; P = .005) at 6 months and by 2.67 points (95% CI, 1.14-4.20; P = .001) at 12 months. Among secondary outcomes, changes in cardiometabolic risk factors were not statistically significant at 1 year. Results from analyses with multilevel multiple imputation for missingness were similar.Conclusions and RelevanceIn this Mediterranean nutrition intervention of multicomponent behavioral/environmental changes, career firefighters had increased adherence to a Mediterranean diet.Trial RegistrationClinicalTrials.gov Identifier: NCT02941757
Printed Divisional Optical Biochip for Multiplex Visualizable Exosome Analysis at Point‐of‐Care
Authors: Yang Xu , Zhang Zeying , Wu Yuanbin , Wang Huadong , Yun Yang , Sun Yali , Xie Hongfei , Bogdanov Bogdan , Senyushkin Pavel , Chi Jimei , Lian Zewei , Wu Dongdong , Su Meng , Song Yanlin 
Published: August 2023

AbstractRapid detection of various exosomes is of great significance in early diagnosis and postoperative monitoring of cancers. Here, a divisional optical biochip is reported for multiplex exosome analysis via combining the self‐assembly of nanochains and precise surface patterning. Arising from resonance‐induced near‐field enhancement, the nanochains show distinct color changes after capturing target exosomes for direct visual detection. Then, a series of divisional nanochain‐based biochips conjugated with several specific antibodies are fabricated through designed hydrophilic and hydrophobic patterns. Because of the significant wettability difference, one sample droplet is precisely self‐splitting into several microdroplets enabling simultaneous identification of multiple target exosomes in 30 min with a sensitivity of 6 × 107 particles mL−1, which is about two orders lower than enzyme‐linked immunosorbent assay. Apart from the trace amount detection, excellent semiquantitative capability is demonstrated to distinguish clinical exosomes from glioblastoma patients and healthy people. This method is simple, versatile, and highly efficient that can be extended as a diagnostic tool for many diseases, promoting the development of liquid biopsy.
Harnessing Aromatic‐Histidine Interactions through Synergistic Backbone Extension and Side Chain Modification
Authors: Yu Zhen , Kreitler Dale F. , Chiu Yin Ting T. , Xu Ruiwen , Bruchs Austin T. , Bingman Craig A. , Gellman Samuel H. 
Published: August 2023

AbstractPeptide engineering efforts have delivered drugs for diverse human diseases. Side chain alteration is among the most common approaches to designing new peptides for specific applications. The peptide backbone can be modified as well, but this strategy has received relatively little attention. Here we show that new and favorable contacts between a His side chain on a target protein and an aromatic side chain on a synthetic peptide ligand can be engineered by rational and coordinated side chain modification and backbone extension. Side chain modification alone was unsuccessful. Binding measurements, high‐resolution structural studies and pharmacological outcomes all support the synergy between backbone and side chain modification in engineered ligands of the parathyroid hormone receptor‐1, which is targeted by osteoporosis drugs. These results should motivate other structure‐based designs featuring coordinated side chain modification and backbone extension to enhance the engagement of peptide ligands with target proteins.
Synthesis of Axially Chiral QUINAP Derivatives by Ketone‐Catalyzed Enantioselective Oxidation
Authors: Jiang Peng‐Ying , Wu San , Wang Guan‐Jun , Xiang Shao‐Hua , Tan Bin 
Published: August 2023

AbstractQUINAPs have emerged as a pivotal class of axially chiral compounds with remarkable features in the stereoinduction of diverse enantioselective transformations. However, the confined substrate range and extravagant price still pose challenges, limiting their broader utilization. Herein, we describe the first atroposelective oxidation of an N atom using a chiral ketone catalyst, allowing the kinetic resolution of QUINAPOs to give both the unreacted substrates and their corresponding N‐oxides with excellent enantioselectivity. Importantly, the enantioenriched products can be readily converted into the QUINAP targets without any loss of stereochemical integrity. Mechanistic investigations indicate that a dioxirane, generated through the oxidation of the ketone with oxone, acts as the active catalytic species. Furthermore, we have successfully extended this catalytic system to the kinetic resolution of QUINOLs and the dynamic kinetic transformation of pyridine analogues of QUINAPO possessing a labile stereogenic axis. The practicality of the developed protocol is further demonstrated by the successful application of QUINAPO N‐oxide as a Lewis base catalyst in a series of enantioselective transformations.
Reducing ammonia permeance in poly(acrylonitrile‐co‐butadiene) (NBR)‐based elastomers
Authors: Zhang Yuecheng , Kentish Sandra , Scholes Colin A. 
Published: August 2023

AbstractAmmonia (NH3) has emerged as a sustainable future fuel for a low‐carbon future. Ideally, the transportation and storage of ammonia in re‐purposed natural gas networks will dramatically reduce the economic burden associated with converting to ammonia. However, the highly condensable nature and small kinetic diameter of the ammonia means that this fuel readily permeates through the polymer‐based elastomers and gaskets used in natural gas infrastructure. To mitigate this issue, three kinds of additives have been incorporated into the conventional natural gas elastomer poly(acrylonitrile‐co‐butadiene) (NBR) to reduce ammonia permeance. The first is based on increasing the basicity of the elastomer environment, the second provides chemical reactivity with ammonia to limit transport, and the third uses barrier additives to prevent diffusion. The mechanical properties of the modified elastomers; expressed as the tensile stress at yield and Young's modulus were studied. The creation of a basic environment through the addition of amines resulted in moderate changes in ammonia permeability, with up to 50% reduction of ammonia permeability observed from putrescine added NBR. Chemical additives lowered the permeability by up to 20% with limited impact on the tensile properties. The addition of 3% graphene oxide to NBR had the most significant decrease in ammonia permeability, 80%, but also produced a more rigid material. The investigation shows that ammonia permeability can be significantly reduced in NBR elastomers, through the addition of inexpensive additives in tailored strategies.
Recurrent staphylococcal scalded skin syndrome in a 20‐month old—A case report
Authors: Basurto Camille , Baah‐Owusu Nada , Berreth Kyla 
Published: August 2023

Key Clinical MessageWe present a case of a 20‐month‐old child with a history of atopic dermatitis that exhibited recurrent erythematous‐bullous lesions consistent with Staphylococcal Scalded Skin syndrome (SSSS). SSSS is an exfoliative toxin‐mediated skin disorder most commonly found in children. In this paper, we discuss the importance of recognizing the clinical symptomatology and progressive nature of SSSS, particularly in patients with a history of atopic dermatitis, to ensure prompt treatment and resolution of the syndrome.
FDA Modernization Act 2.0: An insight from nondeveloping country
Authors: Akash Sajidur Rahman , Arnob M. A. Jobayer Billah , Uddin Md Jamal 
Published: August 2023

AbstractAnimal testing is required in drug development research and is crucial for assessing the efficacy and safety of medications before they are commercialized. However, the newly furnished Food and Drug Administration Modernization Act 2.0 has given new insight into drug development. It opens a new door by offering an alternative testing method for developing a new drug without using animals. This newly proposed system may potentially significantly impact nondeveloped countries worldwide. In this study, we explore the alternative testing options such as in silico modeling, human tissue‐on‐chip engineering, animal‐free recombinant antibodies, tissue engineering, and artificial intelligence presented by this act and discuss its implications for nondeveloped countries.
Irreversible Structural Phase Transition in [(9‐triptycylammonium) ([18]crown‐6)][Ni(dmit)2]: Origin and Effects on Electrical and Magnetic Properties
Authors: Manabe Jun , Sako Nagisa , Ito Mizuki , Fujibayashi Masaru , Kato Chisato , Cosquer Goulven , Inoue Katsuya , Takahashi Kiyonori , Nakamura Takayoshi , Akutagawa Tomoyuki , Shimono Seiya , Ishibashi Hiroki , Kubota Yoshiki , Nishihara Sadafumi 
Published: August 2023

AbstractMaterials exhibiting irreversible phase transitions, leading to changes in their properties, have a potential for novel application in electronic components such as a non‐rewritable high‐security memory. Here, we focused on the two salts, [(9‐triptycylammonium)([18]crown‐6)][Ni(dmit)2] (1) and [(9‐triptycylammonium)([15]crown‐5)][Ni(dmit)2] (2), which featured 2D sheet structures with alternately stacked cation and anion layers. Both salts exhibit similar cation arrangements, however, their anion arrangements differ significantly. The temperature‐dependent magnetic susceptibilities of 1 and 2 were well reproduced by the alternating chain model (JAC1/kB=−306(8), JAC2/kB=−239(3) K) and the Curie‐Weiss model (θ=−3.9(1) K), respectively. 1 experience a reversible phase transition around 40–60 K, causing anomalies in magnetic behavior. Moreover, an irreversible single‐crystal‐to‐single‐crystal phase transition to 1′ undergo at ~381 K, inducing a rearrangement of [Ni(dmit)2]− anions and a resistivity decrease from 6.5×106 to 6.5×102 Ω cm. The susceptibility curve of 1′ was reproduced by a combination of the Curie‐Weiss and dimer models (Jdimer/kB=−407(5), θ=−26.7(5) K). The irreversible transition of 1 is the first example for such supramolecule and [Ni(dmit)2]− system to our knowledge, in opening potential new‐type materials.
Quality of life after pancreatoduodenectomy: Is the outcome predetermined by the diagnosis?
Authors: Silva Trevor , Wagler Amy , Nelson Daniel , O'Connor Victoria 
Published: August 2023

AbstractBackground and ObjectivesNon‐physiological factors tied to the disease process may drive the diminished quality of life (QoL) after pancreatoduodenectomy (PD). We compared postoperative QoL among patients undergoing PD for either benign or malignant pathology.MethodsFrom 2012 to 2021, 228 patients underwent PD in a large healthcare system. Eighty‐two patients (36.0%) were interviewed using the EORTC QLQ‐C30 questionnaire. A minimum of 6 months after surgery was required for the survey. QoL outcomes were compared based on diagnosis (benign vs. malignant).ResultsPatient mean age was 65 years (21–82), and forty‐seven (57%) were men. Most patients underwent surgery for cancer, 76% (n = 62). Grade B postoperative pancreatic fistula incidence was higher in benign cases (30% vs. 6.5%, p = 0.024). Weight loss was more common in malignancy (79% vs. 50%, p = 0.016). Carcinoma patients felt less useful, hopeful, reported less control of their life and certainty of the future, and were less satisfied with their appearance. Carcinoma patients also reported diminished memory, fear of relapse, and greater financial burden.ConclusionsLong‐term QoL is inferior in PD patients with carcinoma and is driven by the psychological and socioeconomic implications of malignancy. Supportive resources for pancreas cancer patients should be evaluated and optimized.
Temperature‐dependent kinetics of the gas‐phase reactions of Cl atoms with nopinone, ketolimonene, and myrtenal
Authors: Fakih Mariam , Roth Estelle , Tomas Alexandre , Chakir Abdelkhaleq 
Published: August 2023

AbstractIn this study, the gas phase reaction of chlorine atoms with three first‐generation oxidation products of monoterpene: (myrtenal C10H14O, nopinone C9H14O, and ketolimonene C9H14O) were investigated using a relative technique method. These compounds result from the atmospheric oxidation of monoterpene compounds such as α/β – pinene and limonene. Experiments were performed at temperature range 298–353 K and atmospheric pressure in synthetic air bath gas. Cl atoms were generated by UV photolysis of dichloride (Cl2). The reaction was followed using a proton‐transfer reaction mass spectrometer (PTR‐MS) and/or Fourier‐transform infrared spectroscopy (FTIR) to monitor the concentrations of the investigated species simultaneous with several reference compounds as a function of time. The rate constants were obtained and the Arrhenius expressions (cm3 molecule−1 s−1) obtained were established over the temperature range of 298–353 K:knopinone + Cl =  (5.0  ±  1.2) ×  10−10 exp ( − (406  ±  78) /T)kketolimonene + Cl =  (8.88 ±  1.3) × 10−10 exp( − (246 ± 46)/T)kmyrtenal + Cl =  (13.5 ±  6.4) × 10−10 exp( − (535 ±  153)/T)Based on rate constants, the atmospheric lifetimes (τ) of targeted compounds with respect to reaction with chlorine atoms were estimated and expected to be less than 1 day. There results led to conclude that the reaction with chlorine atoms can be an effective tropospheric loss pathway mainly in regions presenting relatively high chlorine concentrations.
How Does Oxymetazoline Change Nasal Aerodynamics and Symptomatology in Patients with Turbinate Hypertrophy?
Authors: Root Zachary T. , Lepley Thomas J. , Wu Zhenxing , Chapman Robbie J. , Schneller Aspen R. , Formanek Veronica L. , Kelly Kathleen M. , Otto Bradley A. , Zhao Kai 
Published: August 2023

ObjectivesOxymetazoline relieves nasal obstructive symptoms via vasoconstriction, however, the changes in nasal structures and aerodynamics that impact symptoms the most remain unclear.MethodsThis prospective, longitudinal, and single blinded cohort study applied Computational Fluid Dynamic (CFD) modeling based on CT scans at baseline and post‐oxymetazoline on 13 consecutive patients with chronic nasal obstruction secondary to inferior turbinate hypertrophy from a tertiary medical center. To account for placebo effect, a sham saline spray was administered with subject blindfolded prior to oxymetazoline, with 30 min rest in between. Nasal Obstruction Symptom Evaluation (NOSE) and unilateral Visual Analogue Scale (VAS) scores of nasal obstructions were collected at baseline, after sham, and 30 min after oxymetazoline.ResultsBoth VAS and NOSE scores significantly improved from baseline to post‐oxymetazoline (NOSE: 62.3 ± 12.4 to 31.5 ± 22.5, p < 0.01; VAS: 5.27 ± 2.63 to 3.85 ± 2.59, p < 0.05), but not significantly from baseline to post‐sham. The anatomical effects of oxymetazoline were observed broadly throughout the entire length of the inferior and middle turbinates (p < 0.05). Among many variables that changed significantly post‐oxymetazoline, only decreased nasal resistance (spearman r = 0.4, p < 0.05), increased regional flow rates (r = −0.3 to −0.5, p < 0.05) and mucosal cooling heat flux (r = −0.42, p < 0.01) in the inferior but not middle turbinate regions, and nasal valve Wall Shear Stress (WSS r = −0.43, p < 0.05) strongly correlated with symptom improvement.ConclusionOxymetazoline broadly affects the inferior and middle turbinates, however, symptomatic improvement appears to be driven more by global nasal resistance and regional increases in airflow rate, mucosal cooling, and WSS, especially near the head of the inferior turbinate.Level of Evidence3: Well‐designed, prospective, single blinded cohort trial. Laryngoscope, 134:1100–1106, 2024
The phantom of the author: predatory publisher OMICS is ghost‐writing its own articles
Authors: Downes Mike 
Published: August 2023

Key points
OMICS has a number of subsidiaries or imprints.
All of them have been producing fake articles for the past 3 years.
Most of the fake articles are collages of plagiarized material with fake authors and invalid emails.
It is estimated that there could be more than 100,000 such articles.
Academics should not be publishing with OMICS.
Universities and research agencies should enact deterrent policies.