bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pineal cyst-related sleep disorders – a narrative review
Authors: Gałązka Jakub Krzysztof , Domagalski Łukasz , Hoffman Zofia , Homa Piotr , Kaleta Natalia , Drabczyńska Katarzyna , Czyżewski Wojciech 
Published: May 2023

The pineal gland is an endocrine gland, which is responsible for the human circadian rhythm, through the regulation of its hormone – melatonin. The most common pathology of a pineal gland is pineal cyst – its population incidence is estimated as 1-23%, depending on the publication. The most common symptoms of a pineal cyst include headache (87%), visual field defects (54%), nausea/vomiting (34%), and dizziness/vertigo (31%). Among the majority of patients with the asymptomatic pineal cyst, the wait-and-see strategy is proper.
According to the newest meta-analyze, the prevalence of sleep disturbances among patients with pineal cyst estimates to be 17%. The results of direct melatonin level measurements in pineal cysts remain unclear. The study focused on sleep disturbances in pediatric patients with pineal cysts and showed a significantly higher score on Sleep Disturbance Scale for Children (SDSC) in the domains of disorders of excessive sleepiness and disorders of initiating and maintaining sleep than the control groups. The impact of lesion on sleep quality correlated with its size.
The pineal cyst may be considered a rare, and potentially reversible, cause of sleep disorders. Nevertheless, according to the present reports (often opposite to each other), this thesis and the mechanism of its occurrence need to be further researched.
Possible sexual dysfunction in traumatically injured clients: improving the approach at initial assessment
Authors: Brine Jennifer 
Published: May 2023

Aim: To explore the perceived barriers experienced by rehabilitation case managers to discussing sexual function with clients after a traumatic injury, at the point of initial assessment. Study design: Small-scale semi-structured interviews were conducted to inform baseline measures for a service improvement proposal within the author's employing company. A qualitative phenomenological methodology was used for the interpretation of the data, with application of framework analysis. Findings: Case managers within the company do not routinely ask clients about issues of sexual dysfunction at the initial assessment of rehabilitation needs. Identified inhibitors included the client's age, cultural background, the presence of other people during the assessment, embarrassment for either party, or any apparent reservations about the assessment process for the client. These echoed findings from the wider healthcare literature. Prompts to initiating conversations were also identified, including the nature of injury or the openness of the client. Conclusion: In their holistic assessment of clients' rehabilitation needs, and as part of the development of the therapeutic relationship, case managers are ideally situated to encourage conversations concerning issues of sexual dysfunction with clients, having the opportunity to signpost them to the most appropriate support or to facilitate referrals for treatment.
Pain experience of cancer patients receiving care in a multidisciplinary pain management clinic
Authors: Alsaraireh Mahmoud , Eshah Nidal , Alkhawaldeh Abdullah , ALBashtawy Mohammed 
Published: May 2023

Background: Few longitudinal studies have focused on patients' cancer pain experience when receiving care in a multidisciplinary pain management clinic (MPMC). This study aimed to evaluate the experiences of a cohort of cancer patients newly engaged in a MPMC. Methods: This study was based on a longitudinal approach in which data were collected over a 6 months period at the King Hussein Cancer Centre in Jordan. The study adopted the Arabic version of the Brief Pain Inventory to identify the level and prevalence of cancer pain, and to identify the impact of receiving care at the MPMC on patients' pain experience. Data were collected over four time points, and the period between these points ranged from 2 to 3 weeks. Results: The majority of patients demonstrated improvement in their pain after receiving treatment at the MPMC, while a third still experienced severe pain. Significant improvement was reported at T1, and no further decline in pain was noted after this point. This indicates that exposure to the intervention provided by the MPMC generated, on average, an improvement in patients' pain experience. Conclusion: The MPMC may be an effective pain management strategy in the treatment of cancer pain.
Bidirectional terahertz plasmonic switch based on periodically structured graphene
Authors: Dehghan Mehdi , Moravvej-Farshi Mohammad Kazem , Jabbari Masoud , Darvish Ghafar , Ghaffari-Miab Mohsen 
Published: May 2023

A plasmonic crystal structure is proposed and simulated based on graphene at terahertz frequency using the three-dimensional finite element method. The proposed model involves both an ON/OFF and a directional switch. Implementing a crystalline structure in graphene can enhance absorption since such a structure creates a bandgap wherein no propagation mode is allowed. Accordingly, the ON/OFF and directional switches can be designed with an extinction ratio higher than 30 dB. Other advantages of this structure are its high quality factor and small dimensions of 1 µm (for the ON/OFF switch) and 2 µm (for the directional switch).
Assessing SARS-CoV-2-specific T-cell reactivity in late convalescents and vaccinees: Comparison and combination of QuantiFERON and activation-induced marker assays, and relation with antibody status
Authors: Gatti Arianna , Zizzo Gaetano , De Paschale Massimo , Tamburello Antonio , Castelnovo Laura , Faggioli Paola Maria , Clerici Pierangelo , Brando Bruno , Mazzone Antonino 
Published: May 2023

Objectives
Monitoring of SARS-CoV-2 spread and vaccination strategies have relied on antibody (Ab) status as a correlate of protection. We used QuantiFERON™ (QFN) and Activation-Induced Marker (AIM) assays to measure memory T-cell reactivity in unvaccinated individuals with prior documented symptomatic infection (late convalescents) and fully vaccinated asymptomatic donors (vaccinees).

Methods
Twenty-two convalescents and 13 vaccinees were enrolled. Serum anti-SARS-CoV-2 S1 and N Abs were measured using chemiluminescent immunoassays. QFN was performed following instructions and interferon-gamma (IFN-γ) measured by ELISA. AIM was performed on aliquots of antigen-stimulated samples from QFN tubes. SARS-CoV-2-specific memory CD4+CD25+CD134+, CD4+CD69+CD137+ and CD8+CD69+CD137+ T-cell frequencies were measured by flow cytometry.

Results
In convalescents, substantial agreement was observed between QFN and AIM assays. IFN-γ concentrations and AIM+ (CD69+CD137+) CD4+ T-cell frequencies correlated with each other, with Ab levels and AIM+ CD8+ T-cell frequencies, whereas AIM+ (CD25+CD134+) CD4+ T-cell frequencies correlated with age. AIM+ CD4+ T-cell frequencies increased with time since infection, whereas AIM+ CD8+ T-cell expansion was greater after recent reinfection. QFN-reactivity and anti-S1 titers were lower, whereas anti-N titers were higher, and no statistical difference in AIM-reactivity and Ab positivity emerged compared to vaccinees.

Conclusions
Albeit on a limited sample size, we confirm that coordinated, cellular and humoral responses are detectable in convalescents up to 2 years after prior infection. Combining QFN with AIM may enhance detection of naturally acquired memory responses and help stratify virus-exposed individuals in T helper 1-type (TH1)-reactive (QFNpos AIMpos Abshigh), non-TH1-reactive (QFNneg AIMpos Abshigh/low), and pauci-reactive (QFNneg AIMneg Abslow).
Revisión sistemática sobre la influencia de la edad, el género y las variaciones estacionales en el absceso periamigdalino
Authors: Losada-Campa Juan , Benito-Orejas José Ignacio , San Millán-González María , González-Sosto Mariana , Muñoz-Moreno Maria Fe , Santos-Pérez Jaime 
Published: May 2023

Introducción y objetivo: El absceso periamigdalino (AP) es la complicación más frecuente de la amigdalitis aguda. Dadas las discrepancias observadas en la literatura, presentamos una revisión sistemática de la bibliografía, para analizar la prevalencia del AP en nuestro ámbito, en relación a tres factores epidemiológicos: la edad, el sexo y la climatología.
Método: Se realizó una búsqueda bibliográfica sobre la influencia de la edad, el género y la estacionalidad en el AP. Las bases utilizadas fueron PubMed, Cochrane y Medline, sin restricción de tiempo, siguiendo la metodología PRISMA. El registro se llevó a cabo por tres revisores independientes, durante el mes de octubre de 2022.
Resultados: Se obtuvieron, tras excluir duplicados, 289 artículos, de los que tras el cribado que se detalla en la metodología, seleccionamos 23, como parte de la revisión sistemática.
Discusión: En la mayoría de trabajos incluidos, se objetiva un predominio del AP en los hombres, con una ratio hombres/mujeres, variable de 1,16 a 3. Se desconocen las causas de esta diferencia de género.
La edad media de aparición del AP varía, según el estudio, de los 22 a los 39 años.
Aunque con resultados dispares, el AP no parece tener un predominio estacional, sin que podamos descartar una cierta influencia climática.
Conclusiones: El AP es la complicación más frecuente de la amigdalitis aguda. En el adulto, predomina en hombres. La media de edad oscila entre los 22 y 39 años. No parece mostrar preferencia climática.
Phylogenetic analysis of promoter regions of human Dolichol kinase (DOLK) and orthologous genes using bioinformatics tools
Authors: Farooqi Nadia , Rahman Ataur , Ali Yasir , Ali Kishwar , Khan Muhammad Ezaz Hasan , Jones David Aaron , Abdelkarim Mouadh , Ullah Farman , Jalil Fazal 
Published: May 2023

Abstract
The Dolichol kinase (DOLK) gene encodes the polytopic DOLK protein associated with the endoplasmic reticulum (ER) N-glycosylation pathway catalyzing the final step in the biosynthesis of dolichol phosphate. Dolichol phosphate is an oligosaccharide carrier required for N-glycosylation of DOLK protein, with its deficiency leading to a severe hypo glycosylation phenotype in humans which can cause congenital disorders of glycosylation and death in early infancy. The aim of the present study is to identify the phylogenetic relationship between human and ortholog species based on their conserved sequences in DOLK gene. Sequence alignment of DOLK was carried out in this study and the evolutionarily conserved regulatory sequences were identified using bioinformatics. Promoter sequence of human DOLK was compared with orthologous sequences from different organisms. Conserved non-coding sequences (CNS) and motifs in promoter regions were found by analyzing upstream promoter sequences of Homo sapiens DOLK and its orthologous genes in other organisms. Conserved sequences were predicted in the promoter regions in CNS1 and CNS2. Conserved protein sequences were also identified by alignment of the orthologous sequences. Organisms with similar gene sequences are assumed to be closely related and the ER N-glycosylation pathway is conserved in them.
On the compactness and the essential norm of operators defined by infinite tridiagonal matrices
Authors: Caicedo Alexander , Ramos-Fernández Julio C. , Salas-Brown Margot 
Published: May 2023

Abstract
In this article, all sequences

u

{\boldsymbol{u}}

,

v

{\boldsymbol{v}}

, and

w

{\boldsymbol{w}}

that define continuous and compact tridiagonal operators

T

u
,
v
,
w

{T}_{u,v,w}

acting on the weighted sequence space

l

β

2

{l}_{\beta }^{2}

were characterized. Additionally, the essential norm of this operator, and as an important consequence of our results, the essential norm of multiplication operator

M

u

{M}_{u}

acting on

l

β

2

{l}_{\beta }^{2}

spaces was calculated.
Research on pore structures of fine-grained carbonate reservoirs and their influence on waterflood development
Authors: Yang Chichen , Tang Hongming 
Published: May 2023

Abstract
Carbonate reservoir has complex pore structures. At present, the influence of pore structure on water flooding mechanism of carbonate reservoirs is insufficient. In this article, a systematic workflow was designed in combination with scanning electron microscope, particle size, physical properties, and water flooding experiments to study the effect of pore structure on water flooding mechanism of fine-grained carbonate rocks. Due to the small particle size and strong heterogeneity, the acid fracturing operations, rather than hydraulic fracturing alone, are necessary to achieve increased production and reservoir reconstruction of carbonate reservoirs. Through this study, the mathematical model of reservoir physical parameters (permeability and porosity) was proposed, and the accuracy of the model was verified by comparing the simulated oil recovery with the experimental results. According to the comparison results, the experimental results are consistent with the simulation results, and their oil recovery efficiency is 33.62 and 31.87%, respectively. Finally, the effect of injection rate on oil production was discussed. It is shown that with the increase in injection rate, the output of displaced oil increases significantly. The cumulative oil production increases from 62.5 to 256.31 mL when the injection rate increases from 100 to 400 mL/min. The findings of this study can help for better understanding of the influencing factors and mechanisms of the development efficiency of carbonate reservoirs.
Thermal properties of AlN (nano) filled LDPE composites
Authors: Tripathi Dinesh 
Published: May 2023

Abstract
The thermal properties of aluminium nitride nano-particles (n-AlN) filled into low-density polyethylene (LDPE) are discussed. Cylindrical specimens were prepared using a melt mixing process. X-ray diffraction was performed to characterize the structural properties of the pellets under investigation. The X-ray diffraction analysis confirms the change in secondary structure, such as crystallinity, of the LDPE due to the dispersion of n-AlN powder. The thermal stability of pure and n-AlN filled LDPE was checked by performing thermo-gravimetric analysis. The analysis confirms an improvement in the thermal stability of LDPE due to n-AlN addition. The thermal conductivity of the samples was measured using a KD2 Pro device (based on the transient hot wire technique of thermal conductivity measurement) at room temperature. Our finding reveals ∼1.36 fold enhancement in the effective thermal conductivity of LDPE due to the addition of 15 vol.% of n-AlN. The room-temperature thermal conductivity data of the investigated pellets were analyzed as a function of n-AlN concentration in the light of available theoretical models and correlations. The variation in thermal conductivity data of LDPE with n-AlN concentration is well explained by the semi-empirical model proposed by Agari and Uno.
Cinnamic acids as promising bioactive compounds for cancer therapy by targeting MAPK3: a computational simulation study
Authors: Bayat Zeynab , Tarokhian Aida , Taherkhani Amir 
Published: May 2023

Abstract

Objectives
Mitogen-activated protein kinase-3 (MAPK3) is the upstream regulator in the MAPK cascade and is involved in many critical signaling pathways and biological processes, such as cell proliferation, survival, and apoptosis. MAPK3 overexpression is linked to onset, development, metastasis, and drug resistance in several human cancers. Thus, identifying novel and effective MAPK3 inhibitors is highly demanded. Herein, we aimed to discover organic compounds from cinnamic acid derivatives as potential MAPK3 inhibitors.

Methods
The binding affinity of 20 cinnamic acids to the MAPK3 active site was tested using the AutoDock 4.0 software. Top-ranked cinnamic acids were ranked based on the ΔG
binding values between the ligands and the receptor’s active site. Interaction modes between top-ranked cinnamic acids and MAPK3 catalytic site were indicated using the Discovery Studio Visualizer tool. Molecular dynamics (MD) simulation was carried out to study the stability of the docked pose for the most potent MAPK3 inhibitor in this study.

Results
Cynarin, chlorogenic acid, rosmarinic acid, caffeic acid 3-glucoside, and cinnamyl caffeate exhibited a salient binding affinity to the MAPK3 active site with the criteria of ΔG
binding <−10 k cal/mol. Further, the inhibition constant value for cynarin was calculated at the picomolar concentration. The docked pose of cynarin within the MAPK3 catalytic domain was stable in 100 ns simulation.

Conclusions
Cynarin, chlorogenic acid, rosmarinic acid, caffeic acid 3-glucoside, and cinnamyl caffeate might be helpful in cancer therapy by inhibiting MAPK3.
Creep-fatigue assessment of martensitic welds based on numerically determined local deformation
Authors: Bender Thorben , Klenk Andreas , Weihe Stefan 
Published: May 2023

Abstract
The low cycle fatigue and creep-fatigue behavior of base material and similar welded joints of martensitic steel Grade 92 were examined in this work. Several low cycle fatigue tests with different loading scenarios: fatigue tests with strain-controlled hold time, fatigue tests with strain-controlled amplitudes, and load-controlled hold times, were performed at 873 K. The tests were evaluated with regard to fatigue lifetime, peak stress, the evolution of relaxation stress or creep strain, and failure location. The effect of amplitude level, hold time modus and hold time length on the lifetime of the specimens was investigated using lifetime and damage assessment methods based on strain energy approaches. The numerical simulations for the determination of the evolution of local strains and stresses were done using a viscoplastic material model of Chaboche type, including a strain energy based damage formulation. For the parameter identification, tests were carried out on the specimens made of base metal, welded joint, weld metal, and with microstructure simulated specimens aiming to obtain representative microstructures of the fine grain, intercritical, and coarse grain heat affected zone. The numerical assessment of the local stress, strain, and damage distribution explains the smaller lifetime of the welded joint specimens.
The crystal structure of 5,5′-diselanediyl-bis(2-hydroxybenzaldehyde), C14H10O4Se2
Authors: Tingting Lin , Qiuling Peng , Meiyun Lv , Mengping Guo 
Published: May 2023

Abstract
C14H10O4Se2, triclinic,

P

1
‾

$P\overline{1}$

(no. 2), a = 6.6836(11) Å, b = 8.9933(11) Å, c = 11.5062(19) Å, α = 77.128(12)°, β = 87.684(14)°, γ = 89.975(12)°, V = 673.65(18) Å3, Z = 2, R

gt
(F) = 0.0564, wR

ref
(F
2) = 0.1512, T = 293 K.
A semiotic model of South Korea’s cultural industry ecosystem: the K-pop industry
Authors: Jeon Hyeong-Yeon , Oh Jang-Geun , Wang Chi-Hyun , Kim Sangwon 
Published: May 2023

Abstract
We explored the need for an ecosystem approach based on relational systems when conducting research on South Korea’s cultural industry. We used Mollard’s (2009. L’ingeniere culturelle. Paris: PUF) idea of the participants in the French cultural system as a key reference and extended it to the notion of the platform, which is the core concept of South Korea’s cultural industry ecosystem (CIE). We also utilized the idea of the “semiotic square of consumption values” from Floch to explicate each platform and participant, which play a significant role in South Korea’s CIE. By defining a role rooted in the relationship and values for each subject (i.e., the production, consumption, authority, and intermediary subjects), we aimed to better understand the ecosystem of the cultural industry and focused on K-pop as a specific aspect of South Korea’s cultural sector by identifying the current identity of each participant.
CONCEIÇÃO DE MIL SAMBAS
Authors: Maia Leandro 
Published: May 2023

Conceição Rosa Teixeira (1940-) compôs mais de mil sambas sem receber educação musical formal nem reconhecimento, oferecendo a oportunidade para entender processos criativos em música popular. O trabalho de Conceição Teixeira toca em questões de gênero, religião, classe e etnia a partir da perspectiva sociológica da produção cultural (BOURDIEU, 1993), articulando reflexões sobre habitus, campo e capital cancional.Palavras-chave: Habitus cancional; Aprendizagem informal; Música popular brasileira; Compositoras cancionistas. CONCEIÇÃO: WOMAN OF A THOUSAND SAMBASAbstract: Conceição Rosa Teixeira (1940-) wrote more than a thousand sambas without receiving formal musical education or recognition. She offers the opportu­nity to understand creative processes in popular music. Her work relates to issues of gender, religion, class and ethnicity from the sociological perspective of cultural production (BOURDIEU, 1993), articulating reflections on habitus, field and capital in songwriting. Keywords: Songwriting habitus; Informal learning; Brazilian popular music; Women songwriters.
A cartografia parece ser mais uma ética (e uma política) do que uma metodologia de pesquisa
Authors: Bedin da Costa Luciano 
Published: May 2023

Redigido a partir de uma fala para o evento Deleuze: modos de usar (2020), este ensaio se sustenta a partir da intuição de que a cartografia, tal qual é verificada na obra de Gilles Deleuze e Félix Guattari, mostra-se mais como uma ética e uma política do que uma metodologia de pesquisa propriamente dita. Para isso, toma como campo de análise fragmentos de livros publicados no final dos anos 1970 e início de 1980, em especial Mil Platôs: capitalismo e esquizofrenia e Diálogos, período em que a cartografia aparece pela primeira vez nas obras dos respectivos autores. Embora pesquisadoras e pesquisadores, especialmente no Brasil, tenham assumido a cartografia como um método de investigação, o que se lê em Deleuze e Guattari é uma série de apontamentos em prol do que poderíamos chamar de uma ética cartográfica, aqui sustentada como um lugar de partida, e não de chegada. O ensaio encerra com um poema coletivo produzido pela(o)s participantes do referido evento, finalizando com uma assertiva que sintetiza o que parece ser o movimento de tal ética: “cartografar é alçar voo”.Palavras-chave: Cartografia; Metodologia; Ética. Cartography seems to be more of an ethics than a research methodologyAbstract: Written from a speech for the event Deleuze: ways to use (2020), this essay is based on the intuition that cartography, as ascertained in the works of Gilles Deleuze and Félix Guattari, shows itself more as an ethics and a policy than a research methodology itself. To this end it takes, as an analytical field, some fragments of books published in the late 1970s and early 1980s, especially A Thousand Plateaus: Capitalism and Schizophrenia and Dialogues, the period when cartography first appears in the works of these respective authors. Although researchers, mainly in Brazil, have taken cartography as a method of investigation, what is really read in the works of Deleuze and Guattari are various notes defending what we could call a cartographical ethics, here in this article supported as a starting place instead of a finishing line. The essay ends with a collective poem, produced by the participants of that event, ending with an assertion that synthesizes what seems to be the movement of such ethics: “cartography is a taking flight”. Keywords: Cartography; Methodology; Ethics.