bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengelolaan Dana Desa Menurut Undang-Undang Nomor 6 Tahun 2014 Tentang Desa (Studi Di Desa Baumata Barat Kecamatan Taebenu Kabupaten Kupang Nusa Tenggara Timur)
Authors: Banunaek Novita Anastasia , Tuba Helan Yohanes , Ratu Udju Hernimus 
Published: June 2023

Desa adalah kesatuan masyarakat hukum yang memiliki batas wilayah yang berwenang untuk mengatur dan mengurus urusan pemerintahan, kepentingan masyarakat setempat berdasarkan prakarsa masyarakat, hak asal usul, dan/atau hak tradisional yang diakui dan dihormati dalam sistem pemerintahan Negara Kesatuan Republik Indonesia. Penyusunan Anggaran Pendapatan dan Belanja Negara (APBN) untuk Desa dihitung berdasarkan jumlah desa dan dialokasikan dengan memperhatikan jumlah penduduk, angka kemiskinan, luas wilayah, dan tingkat kesulitan geografis dalam rangka meningkatkan kesejahteraan dan pemerataan pembangunan desa, regulasi penggunaan dana desa diprioritaskan untuk pembangunan dan pemberdayaan masyarakat. Penelitian bertujuan: (a) Untuk mengetahui dan menganalisis pengelolaan dana desa di Desa Baumata Barat Kecamatan Taebenu Kabupaten Kupang Nusa Tenggara Timur; (b) Untuk mengetahui dan menganalisis faktor penghambat pengelolaan dana desa di Desa Baumata Barat Kecamatan Taebenu Kabupaten Kupang Nusa Tenggara Timur. Penelitian ini termasuk penelitian yuridis empiris yaitu penelitian dengan adanya data-data lapangan sebagai sumber sebagai sumber data utama. Hasil penelitian ini memperlihatkan bahwa pengelolaan dana desa di Desa Baumata Barat Kecamatan Taebenu Kabupaten Kupang bahwa pengelolaan dana desa di Desa Baumata Barat baik dalam tahap perencanaan, pelaksanaan, pengawasan dan evaluasi belum berjalan secara efektif. Pengelolaan dana Desa di Desa Baumata Barat dipengaruhi oleh beberapa faktor penghambat yaitu: (a) Rendahnya sumber daya Manusia dari segi kualitas pemerintahan desa sehingga dalam perencanaan pengelolaan hingga pelaksanaan tidak efektif terhadap program-program yang ada pada desa. (b) Fasilitas sarana dan prasarana yang kurang mendukung.
Tinjauan Yuridis Terhadap Perilaku Kumpul Kebo (Samen Leven) Menurut RUU KUHP
Authors: Amelia Fathia Rizky 
Published: June 2023

Perbuatan kumpul kebo atau samen leven yang terjadi di Indonesia merupakan salah satu perbuatan yang menyimpang dan merusak moral generasi anak bangsa. Perilaku kumpul kebo dinilai tidak sesuai dengan norma, adat istiadat dan agama, terlebih lagi di Indonesia yang sangat menjunjung tinggi kesopanan dan agama. Kemudian perbuatan kumpul kebo sendiri dapat berakibat buruk dan kerugian terlebih bagi kaum wanita yang mana dampak dari perbuatan kumpul kebo tersebut bisa menyebabkan para remaja yang masih belia hamil diluar nikah bahkan melakukan aborsi. Sangat miris jika dikaitkan dengan budaya dan adat istiadat di Indonesia yang menjunjung tinggi nilai ketimuran dan kesopanan.Penyebab terjadinya perilaku kumpul kebo diantaranya, karena kurangnya perhatian dan didikan dari orangtua, pengaruh lingkungan yang tidak baik, tontonan pornografi dan ketidaksiapan menikah secara mental serta terakhir yang menjadi alasan yaitu faktor ekonomi yang mengharuskan seseorang melakukan perbuatan samen leven demi mencukupi kehidupan sehari-hari. Kemudian, secara yuridis pelaku perbuatan kumpul kebo dirasa masih belum mendapatkan sanksi dan aturan tegas. Maka dari itu penulis ingin mengetahui dan mengkaji mengenai peraturan perbuatan kumpul kebo dan kebijakan hukum pidana dalam mengatasi perilaku tersebut. Metode yang digunakan dalam penelitian ini adalah metode yuridis normatif, yaitu memusatkan penelitian pada penelitian kepustakaan, sumber datanya diambil dari buku dan peraturan Undang-Undang. Dari berbagai pro kontra mengenai adanya kebijakan maupun peraturan tentang kumpul kebo, penulis berharap RKUHP dapat lebih melindungi kaum perempuan dan mengurangi tingkat aborsi di Indonesia dengan aturan tegas mengenai perilaku samen leven. Karena dengan adanya aturan tegas yang diterapkan maka akan mengurangi perilaku menyimpang diluar perkawinan dan perilaku seks bebas.
Caracterización químico-nutritiva de especies vegetales consumidas por el tapir amazónico (Tapirus terrestris)
Authors: Naranjo Blanca , Suárez Amaury , Arias Gutierrez Ruth Irene , Tapia Andrés 
Published: June 2023

El tapir amazónico (Tapirus terrestris), es un herbívoro nativo de gran tamaño e importancia alimenticia. Los esfuerzos por su preservación y estudio son importantes como se recordó en el marco del II Congreso Ecuatoriano de Mastozoología y I Congreso Latinoamericano de Tapires, que reconoció los esfuerzos de trabajo desarrollados en la amazonia ecuatoriana. Se presenta el resultado de la caracterización químico-nutritiva de sietes especies vegetales consumidas por T. terrestris, a través de análisis proximal (humedad, grasa, fibra cruda, ceniza, proteína total) utilizando técnicas convencionales. Se realizó el análisis de proteína verdadera y digerible, identificación de azúcares, cuantificación de aminoácidos libres y acidez titulable. También se determinaron minerales usando técnicas de absorción atómica y vitaminas hidrosolubles por Cromatografía líquida de alta presión (HPLC). Se encontraron cantidades apreciables de aminoácidos esenciales; gran variedad de minerales en cantidades diversas; vitamina C, trazas de B2 (Riboflavina) y PP (Nicotinamida). En base a los resultados obtenidos se recomienda el cultivo y manejo de estas especies vegetales como fuente de alimentación animal, considerando que en la amazonia todavía se debe conocer y reconocer la diversidad de fuentes alimenticias que nutren el conocimiento de la ciencia y su relación con las comunidades.
Normas de edición para autores
Authors: Órdenes Azúa Paula 
Published: June 2023

La revista publica trabajos redactados en lengua castellana, alemana, francesa, inglesa, italiana y portuguesa referidos a cualquiera de los ámbitos relativos a la filosofía kantiana o en los que la presencia de esta tenga una relevancia significativa. Exceptuadas las reseñas, las entrevistas, los informes, las convocatorias y los obituarios, todos los contenidos de la revista son sometidos a referato doble ciego. Luego de la admisión de las contribuciones por el equipo editorial de la revista, el proceso de evaluación demora entre 3 y 6 meses.
Las contribuciones deben ser originales y su extensión no podrá superar los 80.000 caracteres con espacios. Las reseñas no excederán los 16.000 caracteres con espacios.
An Economic Analysis of Soybean Production in Rajnandgaon District of Chhattisgarh, India
Authors: Patel Mamta , Pandey Sneha , Wasnik Sumit B. , Parte Jwala 
Published: June 2023

The Present study is to examine An Economic Analysis of soybean Production in Rajnandgaon district of Chhattisgarh, India. The study was undertaken by taking 80 sample farmers during the year 2020-21. To collect information from the sample area, an interview schedule and survey approach were utilized. The objective was achieved by using cost concepts and income measures. The cost of cultivation of soybean was observed highest in case of large farm and lowest in case of marginal farms. The overall cost of production was Rs. 1785.71 per quintal. Gross return from soybean was found to be Rs. 68670.84 per hectare. The net return of overall farmers was observed Rs. 32135.15. The Input-output ratio was highest in case of large farmer 1:2.16 and lowest in case of marginal farmer 1:1.98. None of the soybean farmer was applying potash fertilizer to soybean crops, but it plays an important role in nodule formation. Therefore it is required that farmers should apply potash fertilizer to the soybean crop.
High-risk Prognostic Tumor Features of Squamous Cell Carcinomas in Organ Transplant Recipients Compared With the General Population
Authors: Pandeya Nirmala , Isbel Nicole , Campbell Scott , Chambers Daniel C. , Hopkins Peter , Soyer H. Peter , Jiyad Zainab , Plasmeijer Elsemieke I. , Whiteman David C. , Olsen Catherine M. , Green Adele C. 
Published: June 2023

ImportanceThe extent to which major high-risk features of squamous cell carcinomas (SCCs) in organ transplant recipients (OTRs) differ from SCCs in the general population is not known.ObjectiveTo quantify the relative frequency of perineural invasion, invasion below the dermis, lack of cellular differentiation, and tumor diameter greater than 20 mm in SCCs in OTRs and the general population, by anatomic site.Design, Setting, and ParticipantsThis dual-cohort study in Queensland, Australia, included a cohort of OTRs at high risk of skin cancer ascertained from 2012 to 2015 (Skin Tumours in Allograft Recipients [STAR] study) and a population-based cohort ascertained from 2011 (QSkin Sun and Health Study). The STAR study comprised population-based lung transplant recipients and kidney and liver transplant recipients at high risk of skin cancer recruited from tertiary centers and diagnosed with histopathologically confirmed SCC from 2012 to 2015. The QSkin participants were recruited from Queensland’s general adult population, and primary SCCs diagnosed from 2012 to 2015 were ascertained through Medicare (national health insurance scheme) and linked with histopathology records. Data analysis was performed from July 2022 to April 2023.Main Outcomes and MeasuresPrevalence ratio (PR) of head/neck location, perineural invasion, tumor invasion to/beyond subcutaneous fat, poor cellular differentiation, and tumor diameter greater than 20 mm among SCCs in OTRs vs the general population.ResultsThere were 741 SCCs excised from 191 OTRs (median [IQR] age, 62.7 [56.7-67.1] years; 149 [78.0%] male) and 2558 SCCs from 1507 persons in the general population (median [IQR] age, 63.7 [58.0-68.8] years; 955 [63.4%] male). The SCCs developed most frequently on the head/neck in OTRs (285, 38.6%), but on arms/hands in the general population (896, 35.2%) (P &amp;lt; .001). After adjusting for age and sex, perineural invasion was more than twice as common in OTRs as in population cases (PR, 2.37; 95% CI, 1.70-3.30), as was invasion to/beyond subcutaneous fat (PR, 2.37; 95% CI, 1.78-3.14). Poorly vs well-differentiated SCCs were more than 3-fold more common in OTRs (PR, 3.45; 95% CI, 2.53-4.71), and prevalence of tumors greater than 20 mm vs 20 mm or smaller was moderately higher in OTRs (PR, 1.52; 95% CI, 1.08-2.12).Conclusions and RelevanceIn this dual-cohort study, SCCs in OTRs had significantly worse prognostic features than SCCs in the general population, reinforcing the necessity of early diagnosis and definitive management of SCCs in OTRs.
Clinical Promise of Brain-Phenotype Modeling
Authors: Greene Abigail S. , Constable R. Todd 
Published: June 2023

ImportanceAssessing the link between whole-brain activity and individual differences in cognition and behavior has the potential to offer insights into psychiatric disorder etiology and change the practice of psychiatry, from diagnostic clarification to intervention. To this end, recent application of predictive modeling to link brain activity to phenotype has generated significant excitement, but clinical applications have largely not been realized. This Review explores explanations for the as yet limited practical utility of brain-phenotype modeling and proposes a path forward to fulfill this clinical potential.ObservationsClinical applications of brain-phenotype models are proposed and will require coordinated collaboration across the relatively siloed fields of psychometrics and computational neuroscience. Such interdisciplinary work will maximize the reliability and validity of modeled phenotypic measures, ensuring that resulting brain-based models are interpretable and useful. The models, in turn, may shed additional light on the neurobiological systems into which each phenotypic measure taps, permitting further phenotype refinement.Conclusions and RelevanceTogether, these observations reflect an opportunity: bridging the divide between phenotypic measure development and validation and measure end use for brain-phenotype modeling holds the promise that each may inform the other, yielding more precise and useful brain-phenotype models. Such models can in turn be used to reveal the macroscale neural bases of a given phenotype, advancing basic neuroscientific understanding and identifying circuits that can be targeted (eg, via closed-loop neurofeedback or brain stimulation) to slow, reverse, or even prevent functional impairment.
Transcriptome-Wide Structural Equation Modeling of 13 Major Psychiatric Disorders for Cross-Disorder Risk and Drug Repurposing
Authors: Grotzinger Andrew D. , Singh Kritika , Miller-Fleming Tyne W. , Lam Max , Mallard Travis T. , Chen Yu , Liu Zhaowen , Ge Tian , Smoller Jordan W. 
Published: June 2023

ImportancePsychiatric disorders display high levels of comorbidity and genetic overlap, necessitating multivariate approaches for parsing convergent and divergent psychiatric risk pathways. Identifying gene expression patterns underlying cross-disorder risk also stands to propel drug discovery and repurposing in the face of rising levels of polypharmacy.ObjectiveTo identify gene expression patterns underlying genetic convergence and divergence across psychiatric disorders along with existing pharmacological interventions that target these genes.Design, Setting, and ParticipantsThis genomic study applied a multivariate transcriptomic method, transcriptome-wide structural equation modeling (T-SEM), to investigate gene expression patterns associated with 5 genomic factors indexing shared risk across 13 major psychiatric disorders. Follow-up tests, including overlap with gene sets for other outcomes and phenome-wide association studies, were conducted to better characterize T-SEM results. The Broad Institute Connectivity Map Drug Repurposing Database and Drug-Gene Interaction Database public databases of drug-gene pairs were used to identify drugs that could be repurposed to target genes found to be associated with cross-disorder risk. Data were collected from database inception up to February 20, 2023.Main Outcomes and MeasuresGene expression patterns associated with genomic factors or disorder-specific risk and existing drugs that target these genes.ResultsIn total, T-SEM identified 466 genes whose expression was significantly associated (z ≥ 5.02) with genomic factors and 36 genes with disorder-specific effects. Most associated genes were found for a thought disorders factor, defined by bipolar disorder and schizophrenia. Several existing pharmacological interventions were identified that could be repurposed to target genes whose expression was associated with the thought disorders factor or a transdiagnostic p factor defined by all 13 disorders.Conclusions and RelevanceThe findings from this study shed light on patterns of gene expression associated with genetic overlap and uniqueness across psychiatric disorders. Future versions of the multivariate drug repurposing framework outlined here have the potential to identify novel pharmacological interventions for increasingly common, comorbid psychiatric presentations.
The work of bearing witness to the dual pandemics of COVID‐19 and white rage
Authors: Sessoms Amber M. 
Published: June 2023

AbstractThis article explores the impact of the dual pandemics of COVID‐19 and White rage on critical consciousness‐raising. It argues for a reimagining of our democracy as a practice for collective liberation. This article then outlines a framework for social justice that moves beyond liberalism to self‐interrogation, centering historically minoritized voices, and accountability.
Impact of Fluorine‐Based Lithium Salts on SEI for All‐Solid‐State PEO‐Based Lithium Metal Batteries
Authors: Li Jiajia , Hu Haiman , Fang Wenhao , Ding Junwei , Yuan Du , Luo Shuangjiang , Zhang Haitao , Ji Xiaoyan 
Published: June 2023

AbstractLiF‐rich solid‐electrolyte‐interphase (SEI) can suppress the formation of lithium dendrites and promote the reversible operation of lithium metal batteries. Regulating the composition of naturally formed SEI is an effective strategy, while understanding the impact and role of fluorine (F)‐based Li‐salts on the SEI characteristics is unavailable. Herein, LiFSI, LiTFSI, and LiPFSI are selected to prepare solid polymer electrolytes (SPEs) with poly(ethylene oxide) and polyimide, investigating the effects of molecular size, F contents and chemical structures (F‐connecting bonds) of Li‐salts and revealing the formation of LiF in the SEI. It is shown that the F‐connecting bond is more significant than the molecular size and F element contents, and thus the performances of cells using LiPFSI are slightly better than LiTFSI and much better than LiFSI. The SPE containing LiPFSI can generate a high amount of LiF, and SPEs containing LiPFSI and LiTFSI can generate Li3N, while there is no Li3N production in the SEI for the SPE containing LiFSI. The preferential breakage bonds in LiPFSI are related to its position to Li anode, where Li‐metal as the anode is important in forming LiF, and consequently the LiPFSI reduction mechanism is proposed. This study will boost other energy storage systems beyond Li‐ion chemistries.
Customizing 3D Structures of Vertically Aligned Carbon Nanotubes to Direct Neural Stem Cell Differentiation
Authors: Nascimento Luís , Fernandes Cristiana , Silva Ricardo. M. , Semitela Ângela , de Sousa Bárbara M. , Marques Paula A. A. P. , Vieira Sandra I. , Silva Rui. F. , Barroca Nathalie , Gonçalves Gil 
Published: June 2023

AbstractNeural tissue‐related illnesses have a high incidence and prevalence in society. Despite intensive research efforts to enhance the regeneration of neural cells into functional tissue, effective treatments are still unavailable. Here, a novel therapeutic approach based on vertically aligned carbon nanotube forests (VA‐CNT forests) and periodic VA‐CNT micropillars produced by thermal chemical vapor deposition is explored. In addition, honeycomb‐like and flower‐like morphologies are created. Initial viability testing reveals that NE‐4C neural stem cells seeded on all morphologies survive and proliferate. In addition, free‐standing VA‐CNT forests and capillary‐driven VA‐CNT forests are created, with the latter demonstrating enhanced capacity to stimulate neuritogenesis and network formation under minimal differentiation medium conditions. This is attributed to the interaction between surface roughness and 3D‐like morphology that mimics the native extracellular matrix, thus enhancing cellular attachment and communication. These findings provide a new avenue for the construction of electroresponsive scaffolds based on CNTs for neural tissue engineering.
Coordination Chemistry as a Universal Strategy for a Controlled Perovskite Crystallization
Authors: Zuo Weiwei , Byranvand Mahdi Malekshahi , Kodalle Tim , Zohdi Mohammadreza , Lim Jaekeun , Carlsen Brian , Magorian Friedlmeier Theresa , Kot Małgorzata , Das Chittaranjan , Flege Jan Ingo , Zong Wansheng , Abate Antonio , Sutter‐Fella Carolin M. , Li Meng , Saliba Michael 
Published: June 2023

AbstractThe most efficient and stable perovskite solar cells (PSCs) are made from a complex mixture of precursors. Typically, to then form a thin film, an extreme oversaturation of the perovskite precursor is initiated to trigger nucleation sites, e.g., by vacuum, an airstream, or a so‐called antisolvent. Unfortunately, most oversaturation triggers do not expel the lingering (and highly coordinating) dimethyl sulfoxide (DMSO), which is used as a precursor solvent, from the thin films; this detrimentally affects long‐term stability. In this work, (the green) dimethyl sulfide (DMS) is introduced as a novel nucleation trigger for perovskite films combining, uniquely, high coordination and high vapor pressure. This gives DMS a universal scope: DMS replaces other solvents by coordinating more strongly and removes itself once the film formation is finished. To demonstrate this novel coordination chemistry approach, MAPbI3 PSCs are processed, typically dissolved in hard‐to‐remove (and green) DMSO achieving 21.6% efficiency, among the highest reported efficiencies for this system. To confirm the universality of the strategy, DMS is tested for FAPbI3 as another composition, which shows higher efficiency of 23.5% compared to 20.9% for a device fabricated with chlorobenzene. This work provides a universal strategy to control perovskite crystallization using coordination chemistry, heralding the revival of perovskite compositions with pure DMSO.
Tailoring the Amphiphilic Structure of Zwitterionic AIE Photosensitizers to Boost Antitumor Immunity
Authors: Zhang Tianfu , Yang Xing , Ou Xinwen , Lee Michelle M. S. , Zhang Jianyu , Xu Changhuo , Yu Xinghua , Gong Ping , Lam Jacky W. Y. , Zhang Pengfei , Tang Ben Zhong 
Published: June 2023

AbstractAlthough photodynamic therapy (PDT) for thorough cancer treatment is hindered by the limited generation of reactive oxygen species (ROS) with short lifetime from photosensitizers, PDT‐induced antitumor immune response remedies the defects. Previous studies show that inducing immunogenic cell deaths is an attractive approach to activate antitumor immunity, which confers a robust adjuvanticity to dying cancer cells. In this work, amphiphilic luminogens with aggregation‐induced emission characteristics (AIEgens) are rationally designed and synthesized. By modulating the hydrophobic π‐bridge and zwitterionic functional groups, these AIEgens exhibit tunable organelle specificity to lysosome, endoplasmic reticulum, and plasma membrane and enhance ROS generation ability. Notably, the membrane‐targeting AIEgen namely TPS‐2 induces cell death and membrane rupture via PDT to facilitate the release of antigens and activation of immune cells. Furthermore, the size‐controlled TPS‐2 nanoaggregates are found to serve as an adjuvant, promoting antigen accumulation and delivery to sufficiently boost the in vivo antitumor immunity by only one dose injection in a prophylactic tumor vaccination model. This work thus provides new insights into optimizing AIE photosensitizers via a hydrophobicity–hydrophilicity balance strategy for evoking an antitumor immunity and directly suppressing the distanced tumor. A single small‐molecular system for PDT‐stimulated antitumor immunity is envisioned.
Lecithin Reverse Micelle System is Promising in Constructing Carrier Particles for Protein Drugs Encapsulated Pressurized Metered‐Dose Inhalers
Authors: Chang Ziyao , Wang Wenhao , Huang Zhengwei , Huang Ying , Wu Chuanbin , Pan Xin 
Published: June 2023

AbstractProtein drugs contained within pressurized metered dose inhalers (pMDIs) show immense potential for fundamental research and industrial applications, owing to their high bioavailability, convenient administration, and cost‐effectiveness. To deliver protein drugs efficiently, researchers have reached a consensus on the use of carrier particles. However, the main obstacle impeding the commercial availability of pMDI carrier particles is their low stability. This instability is primarily attributed to particle aggregation caused by the Ostwald ripening phenomenon and chemical degradation by water sensitivity of protein drugs. This study proposes the utilization of lecithin, a carrier material possessing an amphiphilic structure, to overcome this bottleneck. By constructing lecithin‐based reverse micelle systems with protein drugs encapsulated within the high‐polarity microdomain, this work anticipates an improvement in the stability of carrier particles within pMDIs. Specifically, the formation of crystalline phases in the reverse micelle systems can control carrier particle size through crystalline self‐limiting effect, preventing particle aggregation. Additionally, the low‐polarity microdomain of the carrier serves as a hydrophobic barrier, shielding protein drugs from water and preventing chemical degradation. Consequently, this work believes that the lecithin‐based reverse micelle system holds significant potential in providing new theoretical insights and experimental support for the advancement of pMDIs containing protein drugs.