bluuebunny/crossref_metadata_2025_split huggingface dataset:
PATHOCOMPLEX OF PATHOGENIC FUNGUS IN TABLE CARROT AND RHIZOSPHERE DEPENDING ON A GROWING REGION
Authors: Sokolova Lyubov M. , Beloshapkina Olga О. , Rubtsov Alexander A. 
Published: January 2023

In the pathocomplex of any agricultural crop, there are different micromycetes, the composition of which varies depending on weather and climatic conditions, seasonal changes. The fungus A. dauci (J. G. Kühn) Groves et Skolko is one of the most harmful pathogens on table carrots, affecting leaves, petioles, and stems. A. radicina Meier, Drechsler et E. D. Eddy damages carrot root crops during storage, causing a hard rot, coal-black, sharply delimited from healthy tissue.
These pathogens occur everywhere and simultaneously; n addition, the optimal conditions for the development of both pathogens are similar. Yield losses from Аlternariа can reach 40–99 %. The complex of fungal species of the genus Fusarium is a ubiquitous soil pathogen of agricultural crops with a wide phylogenetic and ontogenetic specialization, which causes destructive vascular wilting, rot, and necrosis.
The most common are F. oxysporum and F. avenaceum, the latter can also exist as a saprotroph. As a result of the work done, the released mycelium for drawing up the palette is described. It was revealed that the colonies of fungi with light-colored mycelium (54.8%) were larger in the samples from the Voronezh region, which were based on species of the genus Fusarium. In the Moscow region with sufficient moisture, isolates of fungi with light-colored mycelium slightly dominated (43.7 %). In the Rostov region, the frequency of occurrence of isolates of fungi with dark-colored mycelium was on average 58.1%, dominated by fungi of the genus Alternaria.
Non-pharmacological intervention in the treatment of insomnia – the efficacy of weighted blankets
Authors: Sroczyńska Monika , Luchowska Anna , Żaczek Aleksandra 
Published: January 2023

Introduction
Insomnia is a common sleep disorder characterized by difficulty falling asleep, staying asleep, or getting restful sleep. Research suggests that 30-50% of adults experience sleep problems. Chronic lack of sleep has been linked to a range of negative health outcomes, including obesity, hypertension, diabetes, stroke, coronary heart disease and increased mortality. One promising non-pharmacological treatment for sleep issues is the use of weighted blankets. Weighted blankets provide deep pressure stimulation that can relax the body and promote sleep, making them a useful tool for people with insomnia.

Aim of the study
The purpose of this study was to investigate the effectiveness of weighted blankets as a non-pharmacologic intervention for treating insomnia.

Materials and methods
A search was conducted using PubMed and Google Scholar databases. Articles were searched in English using the following key words: weighted blankets; insomnia; sleep.

Results
Weighted blankets resulted in significant improvements in Insomnia Severity Scale scores. The blankets made it easier to fall asleep, improved sleep quality and provided a higher level of rest in the morning. They also reduced stress levels while falling asleep and increased feelings of relaxation. There was an increase in daytime activity levels and a reduction in daytime fatigue symptoms observed. The use of weighted blankets improved daytime functioning and reduced the consumption of sleep medications in people with psychiatric comorbidities who suffered from insomnia. No negative effects on vital signs or serious side effects were found.

Conclusions
Findings indicate that weighted blankets are an effective, safe and clinically meaningful treatment for insomnia.
Short-term and Long-term Outcomes of a Disruption and Disconnection of the Pancreatic Duct in Necrotizing Pancreatitis: A Multicenter Cohort Study in 896 Patients
Authors: Timmerhuis Hester C. , van Dijk Sven M. , Hollemans Robbert A. , Sperna Weiland Christina J. , Umans Devica S. , Boxhoorn Lotte , Hallensleben Nora H. , van der Sluijs Rogier , Brouwer Lieke , van Duijvendijk Peter , Kager Liesbeth , Kuiken Sjoerd , Poley Jan-Werner , de Ridder Rogier , Römkens Tessa E.H. , Quispel Rutger , Schwartz Matthijs P. , Tan Adriaan C.I.T.L. , Venneman Niels G. , Vleggaar Frank P. , van Wanrooij Roy L.J. , Witteman Ben J. , van Geenen Erwin J. , Molenaar I. Quintus , Bruno Marco J. , van Hooft Jeanin E. , Besselink Marc G. , Voermans Rogier P. , Bollen Thomas L. , Verdonk Robert C. , van Santvoort Hjalmar C. ,   for the Dutch Pancreatitis Study Group
Published: January 2023

INTRODUCTION:
Necrotizing pancreatitis may result in a disrupted or disconnected pancreatic duct (DPD) with the potential for long-lasting negative impact on a patient's clinical outcome. There is a lack of detailed data on the full clinical spectrum of DPD, which is critical for the development of better diagnostic and treatment strategies.

METHODS:
We performed a long-term post hoc analysis of a prospectively collected nationwide cohort of 896 patients with necrotizing pancreatitis (2005–2015). The median follow-up after hospital admission was 75 months (P25–P75: 41–151). Clinical outcomes of patients with and without DPD were compared using regression analyses, adjusted for potential confounders. Predictive features for DPD were explored.

RESULTS:
DPD was confirmed in 243 (27%) of the 896 patients and resulted in worse clinical outcomes during both the patient's initial admission and follow-up. During hospital admission, DPD was associated with an increased rate of new-onset intensive care unit admission (adjusted odds ratio [aOR] 2.52; 95% confidence interval [CI] 1.62–3.93), new-onset organ failure (aOR 2.26; 95% CI 1.45–3.55), infected necrosis (aOR 4.63; 95% CI 2.87–7.64), and pancreatic interventions (aOR 7.55; 95% CI 4.23–13.96). During long-term follow-up, DPD increased the risk of pancreatic intervention (aOR 9.71; 95% CI 5.37–18.30), recurrent pancreatitis (aOR 2.08; 95% CI 1.32–3.29), chronic pancreatitis (aOR 2.73; 95% CI 1.47–5.15), and endocrine pancreatic insufficiency (aOR 1.63; 95% CI 1.05–2.53). Central or subtotal pancreatic necrosis on computed tomography (OR 9.49; 95% CI 6.31–14.29) and a high level of serum C-reactive protein in the first 48 hours after admission (per 10-point increase, OR 1.02; 95% CI 1.00–1.03) were identified as independent predictors for developing DPD.

DISCUSSION:
At least 1 of every 4 patients with necrotizing pancreatitis experience DPD, which is associated with detrimental, short-term and long-term interventions, and complications. Central and subtotal pancreatic necrosis and high levels of serum C-reactive protein in the first 48 hours are independent predictors for DPD.
Molecular Characteristics of Early-Onset Colorectal Cancer According to Detailed Anatomical Locations: Comparison With Later-Onset Cases
Authors: Ugai Tomotaka , Haruki Koichiro , Harrison Tabitha A. , Cao Yin , Qu Conghui , Chan Andrew T. , Campbell Peter T. , Akimoto Naohiko , Berndt Sonja , Brenner Hermann , Buchanan Daniel D. , Chang-Claude Jenny , Fujiyoshi Kenji , Gallinger Steven J. , Gunter Marc J. , Hidaka Akihisa , Hoffmeister Michael , Hsu Li , Jenkins Mark A. , Milne Roger L. , Moreno Victor , Newcomb Polly A. , Nishihara Reiko , Pai Rish K. , Sakoda Lori C. , Slattery Martha L. , Sun Wei , Amitay Efrat L. , Alwers Elizabeth , Thibodeau Stephen N. , Toland Amanda E. , Van Guelpen Bethany , Woods Michael O. , Zaidi Syed H. , Potter John D. , Giannakis Marios , Song Mingyang , Nowak Jonathan A. , Phipps Amanda I. , Peters Ulrike , Ogino Shuji 
Published: January 2023

INTRODUCTION:
Early-onset colorectal cancer diagnosed before the age of 50 years has been increasing. Likely reflecting the pathogenic role of the intestinal microbiome, which gradually changes across the entire colorectal length, the prevalence of certain tumor molecular characteristics gradually changes along colorectal subsites. Understanding how colorectal tumor molecular features differ by age and tumor location is important in personalized patient management.

METHODS:
Using 14,004 cases with colorectal cancer including 3,089 early-onset cases, we examined microsatellite instability (MSI), CpG island methylator phenotype (CIMP), and KRAS and BRAF mutations in carcinomas of the cecum, ascending colon, transverse colon, descending colon, sigmoid colon, and rectum and compared early-onset cases with later-onset cases.

RESULTS:
The proportions of MSI-high, CIMP-high, and BRAF-mutated early-onset tumors were lowest in the rectum (8.8%, 3.4%, and 3.5%, respectively) and highest in the ascending colon (46% MSI-high; 15% CIMP-high) or transverse colon (8.6% BRAF-mutated) (all P
trend <0.001 across the rectum to ascending colon). Compared with later-onset tumors, early-onset tumors showed a higher prevalence of MSI-high status and a lower prevalence of CIMP-high status and BRAF mutations in most subsites. KRAS mutation prevalence was higher in the cecum compared with that in the other subsites in both early-onset and later-onset tumors (P < 0.001). Notably, later-onset MSI-high tumors showed a continuous decrease in KRAS mutation prevalence from the rectum (36%) to ascending colon (9%; P
trend <0.001), followed by an increase in the cecum (14%), while early-onset MSI-high cancers showed no such trend.

DISCUSSION:
Our findings support biogeographical and pathogenic heterogeneity of colorectal carcinomas in different colorectal subsites and age groups.
Improvement of low‐intensity long‐time running performance in rats by intake of glucosyl hesperidin
Authors: Nagayama Suminori , Aoki Kai , Komine Shoichi , Arai Norie , Endo Shin , Ohmori Hajime 
Published: January 2023

AbstractRecently, the use of ergogenic aids in sports by both athletes and fans has increased. Moreover, the overall demand for new ergogenic aids has increased. Hesperidin is a polyphenol that is useful for improving exercise performance by activating energy generation through β‐oxidation and oxidative phosphorylation in skeletal muscles. However, it is difficult to use this compound as an ergogenic aid because of its poor water solubility and low bioavailability. Glucosyl hesperidin is formed when one molecule of glucose is transferred to hesperidin via glycosyl‐transferase. It is 10,000× more soluble and has 3.7× higher bioavailability than hesperidin. In this study, we assessed whether continuous (14 days) intake of glucosyl hesperidin improves the aerobic exercise capacity of rats during long‐term acute exercise. Although glucosyl hesperidin intake did not improve the performance of high‐intensity running (30 m/min), we did observe improvement in low‐intensity running (15 m/min) (p < 0.05). We demonstrate that in sedentary rats, glucosyl hesperidin intake increased β‐oxidation and oxidative phosphorylation in the skeletal muscle (p < 0.05 and p < 0.01, respectively). Glucosyl hesperidin intake may have created a metabolic state useful for long‐term exercise. In conclusion, the continuous intake of glucosyl hesperidin improved the aerobic exercise capacity of rats during long‐term acute exercise.
Modern structures of military logistic bridges
Authors: Szelka Janusz , Wysoczański Andrzej 
Published: January 2023

Abstract
The growing paste of military operations, as well as the increased involvement of the Armed Forces in countering the ramifications of natural disasters, impacts the design solutions used for military bridging systems. The most vital optimization factor is the speed of deployment to which all the structural solutions are subject. Another determinant is a wide range of the parameters of the gap to be crossed using one bridging structure transported using typical means of transportation, including its width and the height of the banks. There is a worldwide tendency to fill the space between the treadways, making them more solid and thus much more usable for civilian vehicle traffic as well. That in turn makes them a provisional replacement for the damaged bridge infrastructure used by the population. This poses a number of challenges to be tackled by the state-of-the-art line-of-communication (LOC) bridges and both the close- and general support bridges, which seem to assume the tasks of the LOC bridges.
Enhancing retention in care in HIV-infected adolescents during COVID-19 in Mozambique: results from the DREAM program
Authors: Ciccacci Fausto , Ismael Flavio , Chume Veronica , Ruth Lina , Mbula Pedro , Orlando Stefano , Majid Noorjehan Abdul , Marazzi Maria Cristina 
Published: January 2023

Abstract

Introduction
Around 1,7 million adolescents aged 10–19 years worldwide are infected with HIV, 84% of them living in Sub-Saharan Africa. Mozambique is one of the countries with the highest prevalence of HIV in the world. According to UNAIDS, HIV services for adolescents should be tailored and specifically designed for them.

Methods
We aimed to evaluate a package of activities to enhance the retention of HIV-infected adolescent in Mozambique. We retrospectively reviewed routine data from 7 health centers involved in 26 months, from March 2020 to May 2022. A package of tailored interventions was implemented in all the sites. We reviewed activity data from the included centers.

Results
The median number of patients per center was 343 (IQR: 289–466) at the beginning of the period and 395 (IQR: 322–453) at the end. The median overall retention in care and rate of lost to follow-up at the beginning and the end of the period were respectively: 94.2% (IQR 91.9–97.3%) to 99.0% (IQR 96.8–99.5%), 1.5% (IQR 1–3.2%) to 0% (IQR 0.0–0.3%). The total number of deaths increased reaching a plateau after September 2021. All the indicators improved after the beginning of the intervention, also during COVID-19 pandemic.

Conclusions
Our data support the idea that enhancing retention in care for HIV positive adolescents need tailored interventions, based on deep rooting in the specific social context. Tailored intervention can resist external shock such as COVID-19.
Kinetic studies and conditions optimizations for the removal of direct red 80 dye from wastewater using cotton calyx and iron oxide composite
Authors: Nazir Arif , Malik Kainat , Mahmood Zaid , Latif Shoomaila , Imran Muhammad , Iqbal Munawar 
Published: January 2023

Abstract
This study focusses on the adsorption efficiency of cotton pod (Gossypium arboreum) for biosorption of direct red (DR) 80 dye. The effect of dye concentration, pH, shaking time, adsorbent dose and temperature was considered to evaluate the adsorption efficiency of the cheapest raw material on the removal of dye. Various concentrations (10–50 ppm) were examined and maximum percentage removal of the adsorbent was obtained at pH 1 with adsorbent dose of 0.9 g and shaking time of 60 min. To enhance the adsorption efficiency of the adsorbent, the cotton calyx was treated with FeSO4.7H2O and investigated the removal of the raw adsorbent and the composite. It was examined that the removal efficiency of the composite is more than that of raw adsorbent. The composite was more efficient as dye removal reached up to 97%. FTIR of the composite shows an additional peak at 650 cm−1 for presence of Fe-O group and confirmation of composite formation. SEM micrograph showed that the particles in composite are more packed compared to the raw adsorbent. Mathematical models were applied and kinetic studies also have been done to provide better results regarding to the experimental data. It is concluded that the prepared adsorbent could be used as a tool for the removal of toxic pollutants from textile wastewater.
Discontinuity Detection System in Marble: Analysis of the Time-Frequency Characteristics of Ultrasonic P-waves
Authors: Bicakci S. , Citak H. , Gunes H. , Coramik M. , Aydın Y. , Ege Y. 
Published: January 2023

Abstract
This study attempted to determine both the presence and the appearance of the surface of a crack artificially created in a marble block without axial loading or compression by FFT analysis of ultrasonic longitudinal sound waves by scanning the surface. In such respect, the study differs from other studies in the literature. The aim of the study was to minimize marble waste by determining the most appropriate slab cut direction based on the orientation of the fracture or discontinuity within the marble block. During location-controlled scanning of the marble surface, mean longitudinal wave velocity, Young modulus, Poisson ratio and longitudinal wave velocity variation data were obtained using a V-Meter Mark IV™ ultrasonic test device. For each location, longitudinal ultrasonic velocity data was taken at 250 kHz sampling rate and 256 data points were created. Data from the computer environment were subsequently reorganized using the MATLAB software and FFT conversions for such velocity data were obtained for each location. Then, the peaks of the FFT transformation components were determined by using the “Findpeaks” function in MATLAB‘s signal processing toolbox. The number of peaks in the 50-60 kHz range was determined for each location. A single difference was determined between the peak numbers at the locations within the cracked and uncracked regions. By examining the FFT graphs, it was determined that such additional peak occurring in the cracked regions appeared as a second frequency component near the dominant frequency values. Points with secondary frequency were recorded as 1, while all other points were recorded as 0 in a new matrix. Such data matrices created for each sample were examined by visualization in the form of surface graphics. Using these graphics, the orientations of discontinuities within the marble block may be determined according to the scanning surface.
Pain intensity and sexual satisfaction: a comparison of cyanoacrylate adhesive glue and vicryl for episiotomy skin closure in Kano Nigeria
Authors: Abba Usman , Musa Abubakar , Abdullahi Ibrahim S. , Abdullahi Muhammed K. 
Published: January 2023

Background: Episiotomy is a deliberate incision made on the perineum and posterior vaginal wall during vaginal delivery. Mothers that have a new baby are in great need for wound care and pain relief. We assessed and compared pain intensity and sexual satisfaction using cyanoacrylate adhesive glue and vicryl for episiotomy skin closure at AKTH, Kano Nigeria.
Methods: A randomised control trial was conducted among 100 women who had spontaneous vaginal delivery in the labour ward of AKTH from June to October 2019 after randomization into study group I and control group II. Cyanoacrylate and vicryl were used for skin closure following episiotomy and the patients were followed up for pain and sexual satisfaction for 14 days. Data were analysed using SPSS version 21.0 and p<0.05 was set statistically significant.
Results: The mean±SD ages of the women in the study and control groups were 22.71±9.14 and 23.66±9.00 years, respectively. In group I 84% perceived no pain and 72% perceived mild pain in group II during cyanoacrylate adhesive glue procedures. At all-time intervals, pain intensity was lower in group I (p<0.05). A significant difference was observed regarding sexual function between group I and group II (p<0.001) but the difference was not significant in other cases.
Conclusions: Cyanoacrylate glue compared to Vicryl was found to be effective in reducing short-term pain, the need for analgesia and better sexual satisfaction following episiotomy after childbirth.
Clinical and radiological follow up of post-COVID patients in tertiary care centre
Authors: Penmetsa Chinmai Sowmya , Yalamanchili Vijay Krishna , Yendapu Raja Sekhar , Susmitha Pratti Pratti Venkata Sai 
Published: January 2023

Background: COVID-19 is potentially fatal infection caused by novel corona virus SARS COV2.SARS patients may present with a spectrum of symptoms and signs ranging from relatively asymptomatic to fulminant pneumonitis and death. Out of which, most frequent symptoms are cough, fever, myalgia, dyspnoea and altered smell/taste. The primary objective of the study is to describe the clinical evolution and symptoms persistence [at day 30 and day 60] during 2 months follow up in adults with COVID-19 and to follow up the changes in lung radiographic pictures within 2 months after discharge.
Methods: This is an institutional based, prospective clinical observational study conducted in Asram medical college, Eluru from September 2021 to November 2021 on 25 COVID-19 Patients.
Results: In our study two thirds of patients still reported symptoms at day 30 and half of the patients reported symptoms at day 60. Out of 50 patients, 38 (76%) patients had at least one symptom at day 30 and 25 (50%) patients had symptoms at day 60 and 9 (18%) patients had chest X-ray abnormalities during follow-up after 2 months.
Conclusions: Follow up studies of COVID-19 will improve our understanding of natural history of COVID-19 sequelae and enable us to assess the efficacy of therapeutic interventions to mitigate the long-term consequences of COVID-19 It is necessary to follow up these recovered patients for detection and appropriate management towards their psychological, physical and social realm. It is highly important to provide counselling, moral support to restore to normalcy.
A cross sectional study to assess the vaccination practices regarding hepatitis B among health care personnel of a tertiary care hospital in Kashmir
Authors: Gulzar Basina , Fazili Anjum , Shah Rohul Jabeen , Ain Syed Najmul 
Published: January 2023

Background: Vaccination is one of the most successful public health interventions that has saved millions of lives so far. Due to the occupational exposure, health care workers have an increased risk of contracting hepatitis B. Objectives were to assess the vaccination practices regarding hepatitis B among healthcare personnel (HCP) and to study the factors associated with the vaccination practices regarding hepatitis B of these HCP.
Methods: This cross sectional hospital based study was conducted for a period of 1 year at Sher-I-Kashmir Institute of Medical Sciences (SKIMS) among 450 HCP including doctors, nursing staff, laboratory staff and others and the required sample was drawn from each category on the basis of probability proportionate to size technique. Information was collected from participants by using predesigned, pretested structured and validated questionnaire.
Results: It was found that only 34.9% were vaccinated against hepatitis B. The coverage was highest among doctors 55.5% followed by technicians 25.6%, nurses 23.6%. The main reasons for not receiving this vaccine were: taking all necessary precautions (49.1%), hospital does not provide the vaccine (20.8%), not aware about hepatitis B vaccine (20.5 %).
Conclusions: The study revealed that the hepatitis B vaccination coverage of these healthcare personnel was quite low in spite of the importance of the vaccine for healthcare personnel who are always at risk of getting exposed to the virus during their duties.