bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using the ADDIE model to design and develop physical education lessons incorporated with a functional training component
Authors: Li Hailing , Cheong Jadeera Phaik Geok 
Published: September 2023

IntroductionGood physical fitness is the foundation of a healthy lifestyle. For students, the school becomes the main place to improve their physical fitness. The traditional physical education class places little emphasis on improving physical fitness and students’ physical fitness have continued to decline. To address these challenges, this study aimed to design and develop a functional training program that can be incorporated into existing physical education lessons to improve students’ physical fitness levels.MethodsThis study adopted the instructional design framework of the Analysis, Design, Development, Implementation, Evaluation (ADDIE) model to guide the design and development of the functional training program. After development, the program was implemented and evaluated.ResultsThe results showed the program aroused students’ interest and significantly improved students’ physical fitness.ConclusionThis study showed the usefulness of functional training in improving the physical fitness of primary school students. In addition, it provided a reference for how to use functional training in conjunction with the physical education syllabus.
Higher rates of mental health screening of adolescents recorded after provider training using simulated patients in a Kenyan HIV clinic: results of a pilot study
Authors: Concepcion Tessa , Mogere Peter , Ngure Kenneth , Mwathi Njoroge , Njiru Roy , Kipkorir Boaz , Kiptinness Catherine , Maina Gakuo , Owidi Emmah , Owens Tamara , Kohler Pamela , Wagenaar Bradley H. , Dorsey Shannon , Collins Pamela Y. , Velloza Jennifer 
Published: September 2023

BackgroundKenyan adolescent girls and young women (AGYW) experience a dual burden of HIV and common mental disorders (CMD). HIV clinics are a key entry point for AGYW in need of integrated CMD and HIV care; however, rates of screening and referral for CMDs are low. Our objective was to test an evidence-based provider training strategy, simulated patient encounters (SPEs), on CMD service delivery for AGYW in a Kenyan HIV clinic.MethodsThis pilot study was conducted in a public HIV clinic in Thika, Kenya from January to November 2021. The simulated patient encounter (SPE) implementation strategy included case script development from prior qualitative work, patient actor training, and a three-day SPE training including four standardized mock clinical encounters followed by quantitative surveys assessing provider competencies for each encounter. We abstracted medical record data related to HIV and CMDs such as HIV status, reason for visit, CMD screening test performed, and counselling or referral information. We conducted an interrupted time series analysis using abstracted HIV and CMD screening rates from AGYW ages 16–25 years visiting the clinic 7 months before and 3 months after SPE training. We used generalized linear models to assess changes in CMD screening rates after training.ResultsA total of 10 providers participated in the training. Competency ratings improved across four mock encounters (mean score from 8.1 to 13.7) between first and fourth encounters. We abstracted all medical records (n = 1,154) including from 888 (76%) AGYW seeking HIV treatment, 243 (21%) seeking prevention services, and 34 (3%) seeking other services. CMD screening rates increased immediately following training from 8 to 21% [relative risk (RR) = 2.57, 95% confidence interval (CI) = 1.34–4.90, p &lt; 0.01]. The 3 months following the SPE training resulted in an 11% relative increase in CMD screening proportion compared to the 7 months pre-SPE (RR: 1.11, 95% CI: 1.04–1.17, p &lt; 0.01). Finally, 1% of all pre-SPE screens resulted in referral versus 5% of post-SPE screens (p = 0.07).ConclusionThe SPE model is a promising implementation strategy for improving HIV provider competencies and CMD service delivery for adolescents in HIV clinics. Future research is needed to explore effects on adolescent clinical outcomes in larger trials.
Temperature variations in pharmaceutical storage facilities and knowledge, attitudes, and practices of personnel on proper storage conditions for medicines in southern Malawi
Authors: Khuluza Felix , Chiumia Francis Kachidza , Nyirongo Happy Magwaza , Kateka Chifundo , Hosea Raphael Abbuh , Mkwate Westonie 
Published: September 2023

ObjectiveWe assessed the temperature variations in pharmacies and medicine storage areas in southern Malawi and conducted a knowledge, attitude and practices survey for personnel who manage medicine stores in various health facilities.MethodsThis was a longitudinal study design that used installed Tempmate® thermometers in 27 selected health facilities to record temperatures every 15 min for a period of 9 months. In addition, a questionnaire was used to assess the knowledge, attitude, and practices regarding good pharmaceutical storage. Observations were also made on the storage structures of the facilities and compared with the mean kinetic temperature.ResultsStorage temperature ranged from 13.8°C to 42°C with mean kinetic temperature (MKT) being 25.3°C (95% CI 24.4–26.2°C). Mean temperature for public facilities was lower (23.8°C) than the faith-based facilities (25.2°C) and private facilities (26.6°C). In terms of level of health care, lower temperatures were recorded in facilities offering tertiary level of care as compared to secondary and primary care facilities, p &lt; 0.001. For the type of storage facilities, storage-in-a-box unit (SIAB) presented lower temperatures than ordinary storage areas (non-SIAB), p &lt; 0.001. Majority of health workers (69%) had good knowledge on proper storage conditions. Air conditioners and thermometers were available in 88.4 and 76.9% of the facilities, respectively. However, few facilities utilized the air conditioners due to electricity problems. About 46.15% of the participants were able to correctly record temperatures (at least twice a day) for the storage facilities, 23.07% did not properly record while 30.77% of the personnel did not keep temperature records at all. Limited storage space was among the challenges that facilities encounter to maintain proper storage conditions.ConclusionDespite having the necessary knowledge on proper storage conditions, the pharmacy personnel failed to adhere to good pharmaceutical storage practices due to resource limitations. There is a need for stakeholder interventions such as increasing budget allocation to address the challenges faced by the health facilities.
The causal relationship between gut microbiota and type 2 diabetes: a two-sample Mendelian randomized study
Authors: Sun Kewang , Gao Yan , Wu Huaqing , Huang Xiangyan 
Published: September 2023

BackgroundType 2 diabetes mellitus (T2DM) is a commonly observed metabolic anomaly globally, and as of the present time, there's no recognized solution. There is an increasing body of evidence from numerous observational studies indicating a significant correlation between gut flora and metabolic disease progression, particularly in relation to T2DM. Despite this, the direct impact of gut microbiota on T2DM isn't fully understood yet.MethodsThe summary statistical figures for intestinal microbiota were sourced from the MiBioGen consortium, while the summary statistical data for T2DM were gathered from the Genome-Wide Association Studies (GWAS) database. These datasets were used to execute a two-sample Mendelian randomization (MR) investigation. The Inverse Variance Weighted (IVW), Maximum Likelihood, MR-Egger, Weighted Median, and Weighted Models strategies were employed to assess the impact of gut microbiota on T2DM. Findings were primarily obtained using the IVW technique. Techniques like MR-Egger were employed to identify the occurrence of horizontal pleiotropy among instrumental variables. Meanwhile, Cochran's Q statistical measures were utilized to assess the variability or heterogeneity within these instrumental variables.ResultsThe outcomes from the IVW analysis demonstrated that the genus Alistipes (OR = 0.998, 95% confidence interval: 0.996–1.000, and P = 0.038), genus Allisonella (OR = 0.998, 95% confidence interval: 0.997-0.999, P = 0.033), genus Flavonifractor (OR = 0.995, 95% confidence interval: 0.993–0.998, P = 3.78 × 10−3), and genus Haemophilus (OR = 0.995, 95% confidence interval: 0.993–0.998, P = 8.08 × 10−3) all acted as defense elements against type 2 diabetes. Family Clostridiaceae1 (OR = 1.003, 95% confidence interval: 1.001–1.005, P = 0.012), family Coriobacteriaceae (OR = 1.0025, 95% confidence interval: 1.000–1.005, P = 0.043), genus Actinomyces (OR = 1.003,95% confidence interval: 1.001–1.005, P = 4.38 × 10−3), genus Candidatus Soleaferrea (OR = 1.001,95% confidence interval: 1.000–1.002 P = 0.012) were risk factors for type 2 diabetes. False Discovery Rate correction was performed with finding that genus.Allisonella, genus.Alistipes, family Coriobacteriaceaeand T2DM no longer displayed a significant causal association. In addition, no significant heterogeneity or horizontal pleiotropy was found for instrumental variable.ConclusionThis MR study relies on genetic variation tools to confirm the causal effect of genus Flavonifractor, genus Haemophilus, family Clostridiaceae1, genus Actinomyces and genus Candidatus Soleaferrea on T2DM in the gut microbiome, providing new directions and strategies for the treatment and early screening of T2DM, which carries significant clinical relevance. To develop new biomarkers and better understand targeted prevention strategies for T2DM, further comprehensive investigations are required into the protective and detrimental mechanisms exerted by these five genera against T2DM.
Multilayered safety framework for living diagnostics in the colon
Authors: Mecacci Sonia , Torregrosa-Barragán Lucía , Asin-Garcia Enrique , Smith Robert W. 
Published: September 2023

Introduction: Colorectal cancer is the second most deadly cancer worldwide. Current screening methods have low detection rates and frequently provide false positive results, leading to missed diagnoses or unnecessary colonoscopies. To tackle this issue, the Wageningen UR iGEM team from 2022 developed “Colourectal”, a living diagnostic tool for colorectal cancer. Following a synthetic biology approach, the project used an engineered Escherichia coli Nissle 1917 strain capable of binding to tumour cells that detects two distinct cancer biomarkers, and secretes a coloured protein observable in stool. Due to the utilization of genetically modified bacteria in vivo, precautionary biosafety measures were included within a three level safe-by-design strategy.Results: The first genetic safeguard ensured confinement of the living diagnostic to the colon environment by implementing auxotrophy to mucin that is abundant in the colon lining. For this, a synthetic chimeric receptor was generated to ensure expression of essential genes in the presence of mucin. The second strategy limited the viability of the engineered bacteria to the human body, preventing proliferation in open environments. The use of a temperature sensitive kill switch induced bacterial cell death at temperatures below 37°C. The third biocontainment strategy was installed as an emergency kill switch to stop the Colourectal test at any point. By inducing a highly genotoxic response through CRISPR-Cas-mediated DNA degradation, cell death of E. coli Nissle is triggered.Discussion: While the use of engineered microorganisms in human applications is not yet a reality, the safety considerations of our multi-layered strategy provide a framework for the development of future living diagnostic tools.
Some Results on Third-Order Differential Subordination and Differential Superordination for Analytic Functions Using a Fractional Differential Operator
Authors: Abdulnabi Faten Fakher , Al-Janaby Hiba F. , Ghanim Firas , Alb Lupaș Alina 
Published: September 2023

In this study, we explore the implications of a third-order differential subordination in the context of analytic functions associated with fractional differential operators. Our investigation involves the consideration of specific admissible classes of third-order differential functions. We also extend this exploration to establish a dual principle, resulting in a sandwich-type outcome. We introduce these admissible function classes by employing the fractional derivative operator DzαSN,Sϑz and derive conditions on the normalized analytic function f that lead to sandwich-type subordination in combination with an appropriate fractional differential operator.
TINJAUAN YURIDIS BUY BACK GUARANTEE SEBAGAI ALTERNATIF TERHADAP PENYELESAIAN DEBITUR BERMASALAH ATAS KREDIT PEMILIKAN RUMAH BERSUBSIDI PADA BANK (STUDI PADA BANK DI SUMATERA UTARA)
Authors: RANDY TENGKU OCVAN 
Published: September 2023

One of the risk mitigation instruments which mostly used by banks in providing Subsidized/Sejahtera mortgage facilities is the Guarantee Agreement. The Guarantee Agreement is commonly known as the Buy Back Guarantee Agreement or the Guarantee Agreement to Buy Back. This agreement is not only contained in Cooperation Agreement clause between bank and developer, it is also stated in the form of a deed in the form of a Buy Back Guarantee Agreement or a guarantee deed to buy back the object of the house collateral by guarantor or insurer. Buy Back Guarantee agreement as an alternative for loan guarantees, namely the provision of guarantees and transfer of right to developers to buy back home guarantees from debtors who experience non-performing loan with the condition of the Land Title Certificates not being complete or solving certificates on process, the legal correlation between developer and debtor is still in the form of a Sale Binding Agreement and/or Mortgage Certificate has not yet been issued. However, in practice, the implementation of the Buy Back Guarantee still encounters many obstacles, either form developer, debtor, and bank side.
The research employs normative juridical method, namely the method which is based on applicable legal norms sourced from secondary data consisting of primary, secondary, and tertiary legal materials. Aside of that, to complete the research, the author collect the data from interview of related sources, such as the Banking/Creditor, the Subsidized Housing Developer, and the Notary/Land Deed Maker (PPAT).
From the research results it is found that the legal force of the Buy Back Guarantee Agreement as an alternative for non-performing loan settlement in KPR Sejahtera financing does not have executive power as the guarantee deeds that have been regulated and used at guarantee institution. The implementation/execution of the Buy Back Guarantee by the developer in accordance with the agreed agreement must be carried out since the developer receives a notification/request letter from the bank, but in practice, developer almost never carry out buy back on the house collateral directly. The obstacle in implementing the Buy Back Guarantee Agreement in KPR Sejahtera financing are from the developers, debtors, and banks themselves.
IMPLEMENTATION OF FINITE STATE AUTOMATA ON THE DATE TO SEASON CONVERSION ENGINE BASED ON PRANATA MANGSA SEASON CALENDAR
Authors: Iboy Rahmat satria buana , Gata Windu , Bayhaqy Achmad , Sulaeman Okky Robiana , Merlina Nita 
Published: September 2023

The world is now starting the trend of going green or back to nature. The slogan goes green or back to nature can also be interpreted as living in harmony with nature. Our beloved country of Indonesia has implemented a harmonious life with nature, we can find it in the Javanese planting season calendar called Pranata Mangsa. In the pranata mangsa, we are taught the method of living in harmony, especially in an agricultural system. Harmony with nature means harmony between seasons, weather, living things, and types of plants. If everything is applied, there will be harmonization between all elements both from outside and inside so that additional elements such as chemical fertilizers and pesticides in agriculture, which essentially eliminate the harmonization of nature itself, are not needed. The implementation of Finite State Automata on the farming season calendar is expected to be able to educate and make it easier for farmers in particular and the Indonesian people, in general, to able to recognize the farming time and apply it to daily life. The final result of this research is the calendar system that can convert the date and month in the masehi calendar into the period or season of the pranata mangsa system.
Key word : FSA, DFA, calendar, pranata mangsa, season
Implementation of Finite State Automata in Graphic Design Class Process Online
Authors: Hakim Valianda , Gata Windu , Rahayu Sri , Setiawan Hendra , Novitasari Hafifah Bella 
Published: September 2023

The development of technology is growing rapidly, the number of increasingly sophisticated inventions can also help humans in carrying out their activities, one of which is online classes, especially graphic design from various official organizers such as from coursera, udemy, and other organizers. Online graphic design classes are currently in great demand by the general public, especially at the school level, some have to pay a certain nominal, there are also free ones to access the class, besides that the classes offered are starting to vary, ranging from the beginner level to the advanced level also with certain software such as Adobe Photoshop, Figma, and other design applications and also with different systems, online or offline, graphic design is much needed, especially in the world of work such as printing, advertising and other fields. In this study, it was designed by using the FSA (Finite State Automata) method with the TYPE of NFA (Non-deterministic Finite Automata) to help students in the process of online graphic design classes starting from registration on the website to getting a class certificate so that students do not feel confused about what to do after registering, and is expected to make students understand in the process of online graphic design classes, The results of using FSA with nfa type can help students to better understand the flow of the registration process for online graphic design classes, with the creation of an FSA with this type of NFA is also expected to help students in registering online to get a certificate because they have attended an online graphic design class.

Keywords : desain grafis, FSA, NFA, corel, adobe.
The level of stress in pregnant women during hospitalization in the Pregnancy Pathology department
Authors: Postępska Wiktoria , Kanadys Katarzyna , Kęsik Jan Jakub , Ślizień-Kuczapska Ewa , Pilewska-Kozak Anna Bogusława 
Published: September 2023

Introduction and aims. Pregnancy is a physiological state for a woman. However, if pathology develops, the course of pregnancy is affected by both mental and biological stress. Stress experienced during pregnancy may irreversibly alter the cerebral structures in the foetus. Moreover, chronic stress is likely to cause miscarriage, preterm delivery, IUGR, low birth weight, etc.
The aim of the study was to analyse the stress level in hospitalized pregnant women with account forsociodemographic factors.
Material and methods. The study was carried out in a group of 140 pregnant women hospitalized in the Department of Pregnancy Pathology, Independent State Clinical Hospital No.1 in Lublin. Inclusion criteria for the study were: age 18 or older, established pregnancy, and hospitalization for more than 2 weeks in a pregnancy pathology department. The participants were diagnostically surveyed by the Perceptible Stress Scale (PSS-10) and a questionnaire created for the study.
Results. Almost every second (76; 54.3%) pregnant woman demonstrated low level of stress, 13.6% (n=19) respondents showed average level, and high level was detected in 32.1% (n= 45) of the respondents. A statistically significant correlation was found between the level of perceived stress and education (p=0.031), financial situation (p=0.017).
Conclusions. During hospitalization, nearly every third pregnant woman was affected by a high level of stress. The very fact that the health of the child and/or pregnant mother is found to be at risk is already a source of stress for the woman. Higher intensity of stress - statistically significant concerned mothers with professional education and average financial situation. Data from reports in the literature indicate that stress during pregnancy can also negatively affect the health of the psycho-physical diady- mother child. Further research in this area is needed, along with the possibility of taking measures to promote the psychophysical comfort of hospitalized mothers.
التفكير التأملي لدى تلاميذ المرحلة الابتدائية
Authors: سرى ماجد ناصر  , أ.م.د غسان رشيد الصيداوي  
Published: September 2023

هدف البحث الحالي الى التعرف على مستوى امتلاك تلاميذ المرحلة الابتدائية للتفكير التأملي.
لتحقيق هدف البحث تم اعداد اختبار تكون من (21) فقرة موضوعية وموزعة على خمس مهارات وهي (الملاحظة والتأمل، واكتشاف المغالطات، والوصول الى استنتاجات، ووضع حلول مقترحة، وإعطاء تفسيرات مقنعة)، وتم حساب الصدق الظاهري للاختبار من خلال عرضه على مجموعة من المحكمين والخبراء وصدق الاتساق الداخلي في ضوء المؤشرات الاتية (علاقة درجة الفقرة بالدرجة الكلية للاختبار، علاقة الفقرة بالمهارة التابعة لها) اما ثبات الاختبار تم حسابه باستخدام معادلة كيودر – ريتشاردسون ( K - R20 )، وتم تطبيقه في العام الدراسي 2021- 2022 على عينة من تلاميذ الصف السادس الابتدائي في المديرية العامة لتربية محافظة ميسان مكونة من (260) تلميذ، طبق الاختبار لمدة ثلاثة ايام ابتدأ من يوم الاحد الموافق (20/3/2022)، وتم استعمال الوسائل الإحصائية الاتية(معامل الصعوبة، معامل التمييز، فعالية البدائل الخاطئة، مربع كاي، اختبار T-Test لعينة واحدة ولعينتين) بالاستعانة بالحزمة الإحصائية SPSS وتم التوصل الى النتائج الاتية: يوجد ضعف في مستوى امتلاك تلاميذ المرحلة الابتدائية للتفكير التأملي. وقد أوصى الباحثان بعدة توصيات منها: توعية معلمي الرياضيات لأهمية التفكير التأملي لدى التلاميذ كأحد اهداف تدريس الرياضيات المهمة، وكذلك تأهيلهم وتدريبهم عبر الدورات التدريبية. كما وضعت بعض المقترحات منها: اجراء دراسة عن أسباب صعوبات تعلم التفكير التأملي ومدى انتشارها في محافظة بغداد او في محافظات اخرى.
Análise Cientométrica das Publicações da Revista Educar em Revista (2001 a 2020)
Authors: Silva Suely Ferreira , Araújo Paula Carina de 
Published: September 2023

O estudo da pesquisa e história da educação por meio de periódicos científicos, permite ampliar o conhecimento e evidenciar conteúdo importante para o fazer da educação, portanto o objetivo deste artigo foi analisar o periódico Educar em Revista da Universidade Federal do Paraná (UFPR), no período 2001 a 2020. Desenvolve uma pesquisa descritiva, que combina abordagem quali/quantitativa para apresentação e análise dos dados por meio da bibliometria e cientometria. O corpus da pesquisa foi constituído por 1.182 artigos de um universo de 1.208 documentos. Os resultados revelaram o artigo científico como tipologia documental predominante e maior presença de autoria única; coocorrência de termos formada por 265 palavras, 19 cluster, 1245 links; rede de coautoria formada por 186 autores com pelo menos 2 artigos publicados, distribuídos em 150 clusters; rede de cocitação formada por autores que receberam no mínimo 10 citações, com ligação na rede e, predomínio temático para “formação docente”. Conclui-se que o estudo da produção científica continua sendo importante para demonstrar a relevância da comunicação científica na evolução da ciência e do periódico como instrumento de atualização e como base para registrar a contribuição científica dos pesquisadores. A análise da revista, além de contribuir para caracterizar a produção científica em Educação, permitiu identificar a coocorrência dos termos utilizados e a rede de cocitação, com destaque para Focault, Freire, Bordieu, Piaget, Morin, entre outros.