bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGATURAN SANKSI PIDANA PENYALAHGUNAAN NARKOBA BAGI ANAK DI BAWAH UMUR
Authors: Hartanti  , Jalu Pangestu  , Endah Noor Jati  , Anas Miftahul Huda  , Viviana Lorossae  , Petrus Tahta Anggriawan Putra Semana  
Published: January 2023

Children are part a nation for the next generation. Children have the right to get protection from various types of threats that endanger them, including the practice of drug abuse. Drugs are substances or drugs, from plants and other, which are made periodically in the process of synthesis and non-synthesis, which in their use can cause effects such as decreased consciousness, loss of taste, and can cause users experience dependence. The purpose of this study is to determine the regulations governing the criminal sanctions for drug abuse for minors. This research uses qualitative method with a statutory approach. The data used is secondary data in the form of data on cases of children in 2019-2021 obtained through documents of the National Narcotics Agency of the Special Region Yogyakarta. Drug abuse involving minors involved the role of children as drug couriers or drug users, aged between 16-17 years. The first suspect was arrested for a criminal act as a methamphetamine courier, while the second and third suspects were arrested for using gorilla tobacco purchased through online trading. The legal basis for sanctions for narcotics abuse is regulated in Law No. 35 of 2009 and Law No. 11 of 2012.
Utilization of Information and Communication Technologies (ICTs) Among Basic Rural Secondary School Teachers in Katsina Silization of Information and Communication Technologies (ICTs) Among Basic Rural Secondary School Teachers in Katsina State, Nigeria
Authors: Ikwuakam O.T. , Abubakar A. A. , Agwam Y , Iyela A. , Ibrahim M. , Lawal M 
Published: January 2023

The study was conducted in Katsina State with the aim of finding out the extent of utilization of information and communication technologies (ICTs) among basic rural secondary school teachers. Multi-stage sampling procedure was used to sample 260 teachers; structured interview schedule was employed to capture their thoughts on socio-economic characteristics, sources of information, awareness, access, ICTs utilization and constraints. Descriptive (frequency counts, percentages, mean and standard deviation) and inferential statistics (Chi square and Pearson Product Moment Correlation PPMC) were instruments of data analysis. Teachers were mostly males (85.8%), NCE/BED (97.7%) holders with mean age of 34years and 9 years of working experience. Television ( = 2.35) and internet ( = 2.31) were major sources of information with 60.85% having high level of ICTs awareness. Mobile phone ( = 2.08) and internet ( = 1.76) were most accessed ICTs with 53.8% having low level of access to ICTs. Mobile phone ( = 1.71), newspaper ( 1.52) and radio ( = 1.50) as ICTs were mostly utilized. Most (52.3%) teachers had low level of ICTs utilization. Benefits derived were mostly motivation of students ( = 2.45) and facilitating knowledge sharing with colleagues ( = 2.42). Levels of benefits derived (60.4%) and constraints were high and low respectively. Information (r = 0.330), awareness (r = 0.357), benefits (r = 0.162), access (r = 0.770) significantly correlated with respondents’ level of ICTs utilization. Level (52.3%) of ICTs utilization was low notwithstanding that mobile phone; internet, newspaper and radio were mostly utilized.
Evaluasi Pelaksanaan Operasi Kepolisian Aman Nusa II Dalam Penanganan Corona Virus Disease-19 Menuju New Normal Kepolisian Resort Ogan Komering Ilir
Authors: Ramadhan Muhammad Rizki , Mudasir Mudasir , Mardianto Mardianto 
Published: January 2023

Penanggulangan virus corona melalui pencegahan dan penanganan terhadap masyarakat yang masih tidak mengikuti pedoman kesehatan di jalan dan di tempat ramai merupakan tanggung jawab dan amanat kepolisian terkait upaya pencegahan dan penanganan penyebaran COVID. sebuah virus -19 Virus. Tujuan dari penelitian ini adalah untuk mengevaluasi pelaksanaan kegiatan safe Nusa di Kabupaten Ogan Komering Ilir. Penelitian ini merupakan penelitian deskriptif dengan pendekatan kualitatif. Informasi yang digunakan berdasarkan data kualitatif. Berdasarkan temuan investigasi kegiatan/operasi Polres Ogan Komering Iliri Aman Nusa II sebagai bagian dari percepatan tanggap dan pencegahan akibat wabah Virus Corona 2019 (Covid-19) yang terjadi di beberapa negara. Di sebagian wilayah Indonesia termasuk Kabupaten Ogan Iliri (OKI) dilaksanakan mulai tanggal 18 April 2020 sampai dengan 31 Mei 2020 selama 44 (empat puluh empat) hari dengan aman, benar dan lancar. Meski demikian, kegiatan/operasional Aman Nusa II tetap dapat dikatakan aman dan layak apabila anggota perorangan tidak terlibat dalam kegiatan kriminal selama masa pandemi Covid-19. Hal ini dapat dilihat dari dimensi konteks, input, proses, output.
Analisis Pemberdayaan Pekerja Sosial Dalam Kegiatan Rehabilitasi Sosial Korban Narkotika, Psikotropika dan Zat Adiktif di Institusi Penerima Wajib Lapor ( IPWL) Sriwijaya Kabupaten Ogan Ilir
Authors: Yuniarni Nurul , Idris Umiyati , Iriani Atrika 
Published: January 2023

Berdasarkan hasil observasi peneliti di lapangan bahwa pekerja sosial di IPWL SRIWIJAYA hanya berjumlah 1 (satu) orang yang tidak sebanding dengan jumlah klien 80 orang.Selain itu masih kurangnya sosialisasi tentang IPWL dan fungsi IPWL Sriwijayake daerah-daerah. Penelitian ini mempunyai tujuan untuk menganalisis pemberdayaan pekerja sosial dalam merehabilitasi korban penyalahgunaan napza di Institusi Penerima Wajib Lapor (IPWL) SRIWIJAYA Kabupaten Ogan Ilir.Metode yang digunakanyaitu metode deskriftif dengan pendekatan kualitatif.Hasil penelitian disimpulkan bahwa Pemberdayaan Pekerja Sosial dalam Kegiatan Rehabilitasi Sosial Korban Narkotika, Alkohol, Psikotropika, dan Zat Adiktif, di Institusi Penerima Wajib Lapor ( IPWL) Sriwijaya Kabupaten Ogan Ilir sudah dilaksanakan sebagaimana mestinya melalui lima dimensi yaitu pengadaan, pengembangan, pembinaan, penggajian dan pengawasan. Adapun untuk dimensi pengembangan, pembinaan, penggajian dan pengawasan sudah terlaksana dengan baik dan optimal itu terlihat dengan adanya perubahan prilaku yang lebih baik yang terjadi pada klien. Sedangkan dimensi Pengadaan telah terealiasi dengan adanya pengadaan Peksos melalui Pusbangprov Kemensos R.I
Prosedur Penegakan Hukum Tindakan Pertama Tempat Kejadian Perkara Tim Hunter Satuan Samapta Bhayangkara di Resort Kota Palembang
Authors: Marezal Ezar , Syaifuddin M , Indra Dhani 
Published: January 2023

Penelitian ini bertujuan untuk mengetahui dan menganalisis Prosedur Penegakan Hukum Tindakan Pertama Tempat Kejadian Perkara Tim Hunter Satuan Samapta Bhayangkara di Resort Kota Palembang. Penelitian ini merupakan penelitian deskriptif kualitatif. Informan dalam penelitian ini adalah Kepala Satuan Sabhara Polrestabes Palembang; Kepala Unit Patroli Satuan Sabhara Polrestabes Palembang; Komandan Regu Hunter Satuan Sabhara Polrestabes Palembang; Anggota Regu / Tim Hunter Satuan Sabhara Polrestabes Palembang; dan Unsur masyarakat / organisasi kemasyarakatan. Analisis data adalah analisis kualitatif dengan model interaktif. Prosedur Penegakan Hukum Tindakan Pertama Tempat Kejadian Perkara Tim Hunter Satuan Samapta Bhayangkara di Resort Kota Palembang sudah dilaksanakan sesuai prosedur dan ketentuan yang berlaku. Hal tersebut dapat diketahui dari beberapa indikator, yaitu : efisien, efektif, sederhana, konsisten, fleksibel, dan diterima.
Diverse Carbonates in Exoplanet Oceans Promote the Carbon Cycle
Authors: Hakim Kaustubh , Tian Meng , Bower Dan J. , Heng Kevin 
Published: January 2023

Abstract
Carbonate precipitation in oceans is essential for the carbonate-silicate cycle (inorganic carbon cycle) to maintain temperate climates. By considering the thermodynamics of carbonate chemistry, we demonstrate that the ocean pH decreases by approximately 0.5 for a factor of 10 increase in the atmospheric carbon dioxide content. The upper and lower limits of ocean pH are within 1–4 of each other, where the upper limit is buffered by carbonate precipitation and defines the ocean pH when the carbon cycle operates. If the carbonate compensation depth (CCD) resides above the ocean floor, then carbonate precipitation and the carbon cycle cease to operate. The CCD is deep (>40 km) for high ocean temperature and high atmospheric carbon dioxide content. Key divalent carbonates of magnesium, calcium and iron produce an increasingly wider parameter space of deep CCDs, suggesting that chemical diversity promotes the carbon cycle. The search for life from exoplanets will benefit by including chemically more diverse targets than Earth twins.
Effect of mulching on diversity and abundance of natural enemies associated with brinjal (<em>Solanum melongena</em> L.) crop in Mawathagama, Kurunegala (IL1)
Authors: Kumaratenna K. P. S. , Weligamage S. S. , Warnasooriya P. G. A. S. , Hemachandra K. S. 
Published: January 2023

Misuse of insecticides has negative impacts on the environment and human health; hence, a search for non-chemical alternatives for insect pest control is a timely need. Natural enemies play a significant role in suppressing insect pest populations in crops. Mulching has an impact on the diversity of natural enemies in soil, but it has not been adequately documented locally. Thus, this study was conducted to examine the influence of mulches on natural enemies associated with the pests of the brinjal crop. Four mulch materials viz. rice straw, gliricidia (Gliricidia sepium) leaves, weed residues, and black colour polythene, as the treatments, were laid on plots of brinjal crop. Unmulched plots, with and without weeds, were also used as controls. Experimental design was RCBD with three replicates. Soil inhabitants were caught using pitfall traps and soil sampling was undertaken up to 10 cm depth. Foliage insects were collected using sweep netting. The total number of natural enemies significantly (F (5,120) = 5.928, P<0.05) varied between the treatments. The highest mean number of natural enemies was recorded in rice-straw mulch (2.50 plot–1), followed by weed residues (1.19 plot–1), gliricidia (1.10 plot–1), and black polythene (0.10 plot–1). Unmulched plots left with weeds had a higher mean number of natural enemies (1.29 plot–1) than the plots without weeds (0.43 plot–1). Pest abundance was significantly (F (5,120) = 3.897, P <0.05) different between treatments. The highest abundance was recorded in unmulched plots (25.30 plot–1), followed by weed residues (7.95 plot–1), gliricidia (7.76 plot–1), straw (6.50 plot–1), and black polythene (2.0 plot–1). The study concluded that rice-straw mulching favours natural enemies, while black polythene reduces insect pest abundance. Further, the presence of weeds on plots enhances the abundance of natural enemies.
Galectin-8 Downmodulates TLR4 Activation and Impairs Bacterial Clearance in a Mouse Model of Pseudomonas aeruginosa Keratitis
Authors: Ramadan Abdulraouf , Cao Zhiyi , Hassan Mujtaba , Zetterberg Fredrik , Nilsson Ulf J , Gadjeva Mihaela , Rathinam Vijay , Panjwani Noorjahan 
Published: January 2023

Abstract
Pseudomonas aeruginosa provokes a painful, sight-threatening corneal infection. It progresses rapidly and is difficult to treat. In this study, using a mouse model of P. aeruginosa keratitis, we demonstrate the importance of a carbohydrate-binding protein, galectin-8 (Gal-8), in regulation of the innate immune response. First, using two distinct strains of P. aeruginosa, we established that Gal-8−/− mice are resistant to P. aeruginosa keratitis. In contrast, mice deficient in Gal-1, Gal-3, and Gal-9 were fully susceptible. Second, the addition of exogenous rGal-8 to LPS (TLR4 ligand)–stimulated bone marrow-derived macrophages suppressed 1) the activation of the NF-κB pathway, and 2) formation of the MD-2/TLR4 complex. Additionally, the expression level of reactive oxygen species was substantially higher in infected Gal-8−/− bone marrow neutrophils (BMNs) compared with the Gal-8+/+ BMNs, and the P. aeruginosa killing capacity of Gal-8−/− BMNs was considerably higher compared with that of Gal-8+/+ BMNs. In the bacterial killing assays, the addition of exogenous rGal-8 almost completely rescued the phenotype of Gal-8−/− BMNs. Finally, we demonstrate that a subconjunctival injection of a Gal-8 inhibitor markedly reduces the severity of infection in the mouse model of P. aeruginosa keratitis. These data lead us to conclude that Gal-8 downmodulates the innate immune response by suppressing activation of the TLR4 pathway and clearance of P. aeruginosa by neutrophils. These findings have broad implications for developing novel therapeutic strategies for treatment of conditions resulting from the hyperactive immune response both in ocular as well as nonocular tissues.
Implementasi Doktrin Sola Gratia dalam Menuntaskan Amanat Agung
Authors: Sunarko Andreas Sese 
Published: January 2023

Amanat Agung adalah perintah yang diberikan oleh Tuhan Yesus kepada para murid-muridNya sebelum DIA naik ke sorga dan sekarang menjadi tugas orang- orang percaya. Amanat Agung ini merupakan hal yang urgent untuk dilakukan karena menyangkut keselamatan manusia. Essensi dari Amanat Agung adalah menyampaikan berita keselamatan yang bersumber pada Anugerah Allah (Sola Gratia), hal inilah yang menjadi pembeda dari sumber keselamatan lainnya. Melalui artikel ini penulis ingin menyampaikan implementasi doktrin Sola Gratia dalam menuntaskan Amanat Agung. Metode yang penulis gunakan adalah deskriptif kualitatif dengan pendekatan library riset yang menggunakan berbagai sumber -sumber diantaranya buku-buku dan artikel jurnal yang berkaitan dengan artikel ini. Penulis akhirnya menemukan kesimpulan bahwa cara yang efektif untuk menuntaskan Amanat Agung itu adalah menyampaikan Injil yang merupakan anugerah Allah (Sola Grattia) bagi manusia yang di berikan lewat korban penebusan Tuhan Yesus Kristus, bukan karena usaha manusia semata.
Jornalismo Ambiental
Authors: Collato Camila , Kanehide Ijuim Jorge 
Published: January 2023

Resumo: O presente artigo traz, por meio de uma revisão bibliográfica, uma articulação entre Jornalismo, Direitos Humanos e Complexidade, tomando como base o Jornalismo Ambiental. Colocando em diálogo pesquisadores como Milton Santos, Edgar Morin, Adelmo Genro Filho, entre outros, buscamos demonstrar o potencial criativo e transgressor do Jornalismo Ambiental como forma social de conhecimento a ser constituída sob um paradigma científico complexo em construção e como prática (auto)crítica orientada à ação transformadora e conectada à efetivação e promoção dos Direitos Humanos. Para tanto, a identificação da existência de modos do fazer jornalístico ainda associados ao paradigma científico cartesiano e positivista nos propõe a reflexão sobre possíveis funções do Jornalismo Ambiental, enquanto vanguarda conceitual e epistemológica no campo.

Periodismo ambiental: reflexiones sobre el saber, los derechos humanos y la complejidad
Resumen: Este artículo trae, a través de una revisión bibliográfica, una articulación entre Periodismo, Derechos Humanos y Complejidad, a partir del Periodismo Ambiental. Poniendo en diálogo a investigadores como Milton Santos, Edgar Morin, Adelmo Genro Filho, entre otros, buscamos demostrar el potencial creativo y transgresor del Periodismo Ambiental como forma social de conocimiento a constituirse bajo un paradigma científico complejo en construcción y como practica la (auto)crítica orientada a la acción transformadora y conectada a la realización y promoción de los Derechos Humanos. Por lo tanto, la identificación de la existencia de formas de hacer periodismo aún associadas al paradigma científico cartesiano y positivista nos propone la reflexión sobre las posibles funciones del Periodismo Ambiental como vanguardia conceptual y epistemológica en el campo.
Palabras clave: Periodismo Ambiental. Derechos Humanos. Conocimiento. Complejidad.

Environmental Journalism: reflexions about knowledge, human rights and complexity
Abstract: This article brings, by a bibliographic review, an articulation between Journalism, Human Rights and Complexity, based on Environmental Journalism. Through researchers such as Milton Santos, Edgar Morin, Adelmo Genro Filho, among others into dialogue, we seek to demonstrate the creative and transgressive potential of Environmental Journalism as a social form of knowledge to be constituted under a complex scientific paradigm in construction and as a (self)critical practice oriented to transformative action and connected to the realization and promotion of Human Rights. Therefore, the identification of journalistic practices still associated with the Cartesian and positivist scientific paradigm proposes a reflection on possible functions of Environmental Journalism as a conceptual and epistemological vanguard in the field.
Keywords: Environmental journalism; Knowledge; Human rights; Complexity
A evolução terminológica de “pessoas com deficiência” nos níveis de proteção de direitos humanos
Authors: De Nazaré Freitas Matos Hamanda , Wilson Gama Raiol Raimundo , Regina Benassuly Arruda Paula 
Published: January 2023

Resumo: Na presente investigação analisa-se de que modo o entendimento sobre as terminologias apropriadas para se referir às pessoas com deficiência, nos diferentes níveis de proteção dos direitos humanos, impactou e continua impactando na forma como a sociedade enxerga o valor da pessoa com deficiência. Através do método hipotético-dedutivo, realizou-se pesquisa de natureza bibliográfica e documental, no âmbito do sistema ONU, Sistema Interamericano de Direitos Humanos e interno brasileiro. Nela identificou-se como a evolução conceitual de pessoas com deficiência, ocorrida ao longo dos anos nos documentos internacionais, refletiu a passagem do modelo médico para o modelo social na definição de pessoa com deficiência, concretizando a dignidade humana.

La evolución terminológica de las “personas con discapacidad” en los niveles de protección de los derechos humanos
Resumen: En la presente investigación se analiza cómo la comprensión de las terminologías adecuadas para referirse a las personas con discapacidad, en los diferentes niveles de protección de los derechos humanos, ha impactado y continúa impactando la forma en que la sociedad ve el valor de las personas con discapacidad. A través del método hipotético-deductivo, se realizó una investigación bibliográfica y documental, donde se identificó, en el ámbito del sistema de la ONU, el Sistema Interamericano de Derechos Humanos y el interno brasileño, como la evolución conceptual de las personas con discapacidad. ocurrida a lo largo de los años en documentos internacionales, reflejó el tránsito del modelo médico al modelo social en la definición de persona con discapacidad, concretando la dignidad humana.
Palabras clave: Personas con discapacidad. Derechos humanos. Sistemas de proteccion.

The terminological evolution of “persons with disabilities” in levels of human rights protection
Abstract: In the present investigation, it is analyzed how the understanding of the appropriate terminologies to refer to people with disabilities, in the different levels of protection of human rights, has impacted and continues to impact the way society sees the value of people with disabilities. Through the hypothetical-deductive method, a bibliographical and documentary research was carried out, where it was identified, within the scope of the UN system, the Inter-American System of Human Rights and the Brazilian internal, as the conceptual evolution of people with disabilities that occurred over the years in international documents, it reflected the transition from the medical model to the social model in the definition of a person with a disability, concretizing human dignity.
Keywords: People with disabilities. Human rights. Protection systems.
Oxymatrine inhibits the development of radioresistance in NSCLC cells by reversing EMT through the DcR3/AKT/GSK-3β pathway
Authors: Zhang Hong , Cao Yu , Tang Jianming , Wang Rui 
Published: January 2023

IntroductionLung cancer is the leading cause of cancer-associated mortality globally. In particular, non-small cell lung cancer (NSCLC) constitutes the largest percentage of all cases of lung cancer. In clinical practice, radioresistance contributes to poor responses to radiotherapy. Therefore, the demand remains to explore potential novel and effective mechanism underlying radioresistance to improve the efficacy of radiotherapy for NSCLC.Material and methodsWestern blotting was conducted to quantify the protein expression of epithelial-mesenchymal transition markers E-cadherin and vimentin in the A549 cell line. The proliferation of A549 cells was measured using the Cell Counting Kit-8 and colony forming assays. In addition, the apoptosis of A549 cells was analyzed by flow cytometry. Invasion and migration by NSCLC cells was quantified using Transwell and wound healing assays. Plasmids were used to overexpress decoy receptor 3 (DcR3) in A549 cells. Xenograft models were established to measure the extent of NSCLC tumor growth in vivo.ResultsOur study clarified the activation of the DcR3/protein kinase B (AKT)/glycogen synthase kinase 3β (GSK-3β) pathway in radioresistant NSCLC cells. Oxymatrine (OMT) treatment restored radiosensitivity and inhibited irradiation-induced epithelial-mesenchymal transition (EMT), invasion and migration in NSCLC cells through the DcR3/AKT/GSK-3β pathway in vitro. By contrast, OMT treatment promoted the suppressive effects of radiation on the weight and volume of the xenograft tumors in animal models.ConclusionsIn conclusion, OMT suppressed the development of radioresistance in NSCLC cells by promoting radiosensitivity, through the reversal of EMT process by inhibiting the DcR3/AKT/GSK-3β pathway.
Tracheostomy as a component of intensive care for central nervous system diseases
Authors: Karamyshau A. M. , Leonau A. V. , Shcharbakova P. A. , Hrybach A. L. 
Published: January 2023

Objective. To reveal the effective and safe timing of tracheostomy in patients with CNS diseases by comparative assessment of the duration of respiratory support and ICU, the frequency of development ventilator-associated pneumonia, the assessment of the level of consciousness according to the Glasgow Coma Scale (GCS), survival rate, as well as the incidence of complications rate.Materials and methods. A retrospective study was conducted among neurological and neurosurgical patients treated from 2010 to 2017 who underwent tracheostomy. Patients (n=131) were divided into 3 groups depending on the tracheostomy time.Results. The relation between early tracheostomy and the duration of respiratory support, the ICU bed-day, the probability of developing ventilator-associated pneumonia in patients with the central nervous system pathology was revealed; no relationship was found between the tracheostomy time and the neurological outcome and survival rate in this category patients.Conclusion. The use of early tracheostomy in intensive care of patients with the central nervous system pathology is effective, which is proved by a 2,2 times reduction of the duration of mechanical ventilation, by a 1.9 times reduction of the duration of the ICU day, by a 1.6 times lower risk of developing ventilator-associated pneumonia, without affecting outcomes and being safe due to the absence a lot of complications both during and after the surgical intervention.