bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors Predicting Prolonged Mechanical Ventilation in Guillain–Barré Syndrome
Authors: López-Hernández Juan Carlos , Vargas-Cañas Edwin Steven , Galnares-Olalde Javier Andrés , López-Alderete Jorge Alberto , López-Pizano Alejandro , Rivas-Cruz Mijail Adán , Violante-Villanueva Jesús Arturo , Paredes-Aragón Elma 
Published: February 2023

ABSTRACT:Background:Up to 30% of patients with Guillain–Barré syndrome require mechanical ventilation and 5% die due to acute complications of mechanical ventilation. There is a considerable group of patients that will need prolonged mechanical ventilation (considered as >14 days) and should be considered for early tracheostomy. The objective of this study is to identify risk factors for prolonged mechanical ventilation.Methods:We prospectively analyzed patients with Guillain–Barré diagnosis with versus without prolonged mechanical ventilation. We considered clinical and electrophysiological characteristics and analyzed factors associated with prolonged mechanical ventilation.Results:Three hundred and three patients were included; 29% required mechanical ventilation. When comparing the groups, patients with prolonged invasive mechanical ventilation (IMV) have a lower score on the Medical Research Council score (19.5 ± 16.2 vs 27.4 ± 17.5, p = 0.03) and a higher frequency of dysautonomia (42.3% vs 19.4%, p = 0.037), as well as lower amplitudes of the distal compound muscle action potential (CMAP) of the median nerve [0.37 (RIQ 0.07–2.25) vs. 3.9 (RIQ1.2–6.4), p = <0.001] and ulnar nerve [0.37 (RIQ0.0–3.72) vs 1.5 (RIQ0.3–6.6), p = <0.001], and higher frequency of severe axonal damage in these nerves (distal CMAP ≤ 1.0 mV). Through binary logistic regression, severe axonal degeneration of the median nerve is an independent risk factor for prolonged IMV OR 4.9 (95%CI 1.1–21.5) p = 0.03, AUC of 0.774, (95%CI 0.66–0.88), p = < 0.001.Conclusions:Severe median nerve damage is an independent risk factor for prolonged mechanical ventilation.
Validity and reliability of food frequency questionnaire used in age-related eye disease studies in Turkish adults
Authors: Akpınar Şerife , Köksal Eda 
Published: February 2023

AbstractThe present study aimed to perform the validity and reliability study of the Food Frequency Questionnaire (FFQ) on the frequency of foods rich in antioxidant nutrients and used in Age-Related Eye Diseases (AREDs). In the first interview of the study, the first application of FFQ was carried out, and blank forms of Dietary Records (DRs) were given. For the validity of the FFQ, a total of 12 d (3 days * 4 weeks) of DR were taken. For the reliability of the FFQ, a test–retest application was made with an interval of 4 weeks. The daily intake means of antioxidant nutrients, omega 3 and total antioxidant capacity data obtained from both the FFQ and DR were calculated, and the concordance between the two methods was evaluated with the Pearson Correlation Coefficient (PCC) and Bland–Altman graphs. The present study was carried out at Ege University İzmir/Turkey, Department of Ophthalmology, Retina Unit. The study was conducted with individuals aged ≥50 years who suffered from Age-Related Macular Degeneration (n100, 72⋅0 ± 8⋅03 years). The values obtained from the test–retest applications for FFQ reliability were the same. The nutrient intake means obtained from the FFQ were similar or significantly higher than DR (P< 0⋅05). In the Bland–Altman graphical approach, the nutrient data were within the limits of agreement, and the PCCs between the two methods were moderately related. Considered together, this FFQ is a suitable tool for determining the dietary intakes of antioxidant nutrients in the Turkish population.
How the geochemistry of syn-kinematic calcite cement depicts past fluid flow and assists structural interpretations: a review of concepts and applications in orogenic forelands
Authors: Beaudoin Nicolas E. , Lacombe Olivier , Hoareau Guilhem , Callot Jean-Paul 
Published: February 2023

AbstractOrogenic forelands host interactions between deformation and static or migrating fluids. Given their accessibility and dimensions, these areas are not only historic landmarks for structural geology, but they are also areas of prime interest for georesource exploration and geological storage, and loci of potential geohazards. Geochemical techniques applied on cements filling tectonic structures and associated trapped fluids can constrain the temperature, pressure, origin and pathways of fluids during deformation and allow the characterization of the past fluid system. In this review focused on calcite cements, we first present and critically discuss the most used geochemical techniques to appraise specific parameters of the fluid system. Second, we summarize the outcomes of selected case studies where the past fluid system was reconstructed with consideration of tectonics, either at the scale of the individual fold/thrust or at the scale of the fold-and-thrust belt. At first order, the past fluid system evolves in a similar way with respect to the considered stage of deformation, being rather closed to external fluids when deformation is bounded to mesoscale structure development, and opening to vertical flow when thrust and folds develop. In a more detailed view, it seems that the past fluid system evolves and distributes under the influence of the structural style, of the geometry of the major faults and of the lithology of the sedimentary succession. Through this review, we illustrate the concept of geochemistry-assisted structural geology through case studies where the geochemistry of calcite veins constrained subsurface geometries and structural developments in orogenic forelands.
Zoonotic helminths – why the challenge remains
Authors: Thompson R.C.A. 
Published: February 2023

Abstract
Helminth zoonoses remain a global problem to public health and the economy of many countries. Polymerase chain reaction-based techniques and sequencing have resolved many taxonomic issues and are now essential to understanding the epidemiology of helminth zoonotic infections and the ecology of the causative agents. This is clearly demonstrated from research on Echinococcus (echinococcosis) and Trichinella (trichinosis). Unfortunately, a variety of anthropogenic factors are worsening the problems caused by helminth zoonoses. These include cultural factors, urbanization and climate change. Wildlife plays an increasingly important role in the maintenance of many helminth zoonoses making surveillance and control increasingly difficult. The emergence or re-emergence of helminth zoonoses such as Ancylostoma ceylanicum, Toxocara, Dracunculus and Thelazia exacerbate an already discouraging scenario compounding the control of a group of long neglected diseases.
Eco-evolutionary implications of helminth microbiomes
Authors: Salloum P.M. , Jorge F. , Dheilly N.M. , Poulin R. 
Published: February 2023

Abstract
The evolution of helminth parasites has long been seen as an interplay between host resistance to infection and the parasite's capacity to bypass such resistance. However, there has recently been an increasing appreciation of the role of symbiotic microbes in the interaction of helminth parasites and their hosts. It is now clear that helminths have a different microbiome from the organisms they parasitize, and sometimes amid large variability, components of the microbiome are shared among different life stages or among populations of the parasite. Helminths have been shown to acquire microbes from their parent generations (vertical transmission) and from their surroundings (horizontal transmission). In this latter case, natural selection has been strongly linked to the fact that helminth-associated microbiota is not simply a random assemblage of the pool of microbes available from their organismal hosts or environments. Indeed, some helminth parasites and specific microbial taxa have evolved complex ecological relationships, ranging from obligate mutualism to reproductive manipulation of the helminth by associated microbes. However, our understanding is still very elementary regarding the net effect of all microbiome components in the eco-evolution of helminths and their interaction with hosts. In this non-exhaustible review, we focus on the bacterial microbiome associated with helminths (as opposed to the microbiome of their hosts) and highlight relevant concepts and key findings in bacterial transmission, ecological associations, and taxonomic and functional diversity of the bacteriome. We integrate the microbiome dimension in a discussion of the evolution of helminth parasites and identify fundamental knowledge gaps, finally suggesting research avenues for understanding the eco-evolutionary impacts of the microbiome in host–parasite interactions in light of new technological developments.
A review on gait generation of the biped robot on various terrains
Authors: Khan Moh Shahid , Mandava Ravi Kumar 
Published: February 2023

AbstractDay by day, biped robots’ usage is increasing enormously in all industrial and non-industrial applications due to their ability to move in any unstructured environment compared to wheeled robots. Keeping this in mind, worldwide, many researchers are working on various aspects of biped robots, such as gait generation, dynamic balance margin, and the design of controllers. The main aim of this review article is to discuss the main challenges encountered in the biped gait generation and design of various controllers while moving on different terrain conditions such as flat, ascending and descending slopes or stairs, avoiding obstacles/ditches, uneven terrain, and an unknown environment. As per the authors’ knowledge, no single study has been carried out in one place related to the gait generation and design of controllers for each joint of the biped robot on various terrains. This review will help researchers working in this field better understand the concepts of gait generation, dynamic balance margin, and the design of controllers while moving on various terrains. Moreover, the current article will also cover the different soft computing techniques used to tune the gains of the controllers. In this article, the authors have reviewed a vast compilation of research work on the gait generation of the biped robot on various terrains. Further, the authors have proposed taxonomies on various design issues identified while generating the gait in different aspects. The authors reviewed approximately 296 articles and discovered that all researchers attempted to generate the dynamically balanced biped gait on various terrains.
Variability as a functional marker of second language development in older adult learners
Authors: Pfenninger Simone E. , Kliesch Maria 
Published: February 2023

AbstractThis longitudinal study with time-serial data examines for the first time whether different types of intraindividual variation in second language (L2) performance and cognitive functioning are related, and how and when they influence L2 development longitudinally in older adulthood. We analyzed the L2 development of 26 German-speaking adults aged 62–79 who were taught L2 English for 2 × 90 minutes per week over 6 months. At each of the 15 measurements, the participants completed three L2 tasks and eight cognitive measures, and they answered open-ended questions about socioaffective variables such as L2 motivation. Results of generalized additive mixed models and qualitative content analyses showed,inter alia, that L2 variability—rather than inconsistency or dispersion—had a (nonlinear) effect on L2 growth, being especially large during periods of rapid development. The qualitative analyses revealed a blended operation of internal and external states being associated with periods of significant L2 growth.
Effectiveness of quadrivalent HPV vaccination in reducing vaccine-type and nonvaccine-type high risk HPV infection
Authors: Li Chenxi , Hall Thomas G. , Hall John J. , He Wen-Qiang 
Published: February 2023

Abstract
This study aimed to assess human papillomavirus (HPV) vaccine effectiveness (VE) against both vaccine-type and nonvaccine-type high-risk HPV (hrHPV) infection, and duration of protection in United States. The study population was female participants aged 18–35 years with an HPV vaccination history and genital testing for HPV from the National Health and Nutrition Examination Survey, 2007–2016. Participants vaccinated before sexual debut were assessed against 13 nonvaccine-type hrHPV infection including 31/33/35/39/45/51/52/56/58/59/68/73/82. Multivariable logistic regression was used to estimate VE overall, by age at diagnosis, time since vaccination and lifetime sexual partners. A total of 3866 women were included in the analysis, with 23.3% (95% CI 21.3%–25.4%) having been vaccinated (≥1 dose). VE against vaccine-type HPV18/16/11/6 infection was 58% overall, which was mainly driven by those aged 18–22 years (VE = 64%) and 23–27 years (65%). Among participants aged 18–22 years vaccinated before sexual debut, the VE was 47% (23%–64%) against 13 nonvaccine-type hrHPV and 61% (95% CI 36%–77%) against 5 selected nonvaccine-type hrHPV35/39/52/58/59. Both direct effectiveness and cross-protection maintained effective for 5–10 years post vaccination. We also found the prevalence of ever diagnosed cervical cancer among vaccinated was significantly lower (0.46%, 4/874) than that among unvaccinated participants (1.27%, 38/2992). These findings highlight the potential of significant reduction of cervical cancer following the universal HPV vaccination programme.
Planning scope in second language sentence production: Do bilingual speakers plan ahead more in L1 than in L2?
Authors: Frinsel Felicity F. , Hartsuiker Robert J. 
Published: February 2023

AbstractLanguage production is incremental in nature; we tend to plan linguistic chunks prior to articulating the first word of the utterance. Researchers have acquired knowledge about how far ahead sentences are generally planned, but mostly in monolinguals or the speaker's first language (Allum & Wheeldon, 2007; Martin, Crowther, Knight, Tamborello II, & Yang, 2010; Wagner, Jescheniak, & Schriefers, 2010). It is unclear whether the scope of planning is the same in bilinguals, or the speaker's second language. Here, we examined planning scope in Dutch–English bilinguals' sentence production using a paradigm that elicits descriptions of short animations. Analyses of speech onset times and articulation durations suggest that, on the surface, bilinguals have comparable planning scope in L1 and L2. However, in their L2, bilinguals extended their articulation duration, suggesting that they committed early to the initial noun phrase, but produced it more slowly to buy time to plan the next noun phrase.
The analgesic effect of low-dose radiotherapy in treating benign musculoskeletal painful disorders using different energies: A retrospective cohort study
Authors: Abdelmaqsoud Ahmed , Vorotniak Natalia , Strauß Dirk , Hentschel Bettina 
Published: February 2023

Abstract

Introduction:
This retrospective cohort study tries to determine if there is a correlation between the effectiveness of low-dose radiotherapy (LDRT) in treating painful inflammatory or degenerative musculoskeletal disorders (MSDs) and the applied radiotherapy energy.

Patients and Methods:
Between September 2019 and January 2020, a total of 91 patients with either painful inflammatory or degenerative MSDs were treated with LDRT. The inclusion criteria were patients older than 40 years with either painful inflammatory disorders such as epicondylitis humeri, plantar fasciitis or degenerative osteoarticular disorders of the wrist or ankle joints. All patients were treated with a single dose of 0·5 Gy and a total dose of 6·0 Gy (2 to 3 fractions weekly). Patients were divided into two groups. Orthovolt group was treated with 200 Kv, 15 mA and 1 mm copper filtration with different tubes according to the site to treatment using direct fields. The second group included patients treated with Linac machines with opposing fields using energies between 6 and 18 MV. The pain was evaluated before and on the last day of treatment and 4–6 months later using the Numerical Rating Scale.

Results:
91 patients compatible with the inclusion criteria were identified with a median of 60 years. The median duration of symptoms was 6 months. 46% of patients were males, and 54% were females. The Orthovolt group included 49% of the patients and the Megavoltage group 51%. Most of the patients (98%) were previously treated with other methods such as local corticosteroid injection, painkillers or physiotherapy. At the end of the treatment, 60% of the patient’s showed subjective pain relief and only 6% had a complete response. The follow-up conducted 4 to 6 months after the treatment showed that 65% of patients had a complete response and 8% had an improvement. The comparison between both studied groups shows that the used energy does not affect the response either at the end of the treatment or at the second control. The relationship between the aetiology and the early and late responses shows no difference in the early response but a better late response in patients suffering from inflammatory diseases with a p-value of 0·015. The response according to the treated location shows that patients with osteoarthritis of the ankle joint have a worse response in comparison to other examined joints and plantar fasciitis.

Conclusion:
LDRT is an effective analgesic treatment option for both inflammatory and degenerative MSDs. There is no difference in response according to the used energy, and most of the patients show late responses 4 to 6 months after the treatment.
Peanut response to 2,4-D plus glyphosate
Authors: Daramola Olumide S. , Kharel Prasanna , Iboyi Joseph E. , Devkota Pratap 
Published: February 2023

AbstractThe commercialization of crops that are resistant to 2,4-D plus glyphosate provided an opportunity to growers to apply the herbicide postemergence. However, the potential drift injury of these herbicides to peanuts grown near crops that are resistant to 2,4-D plus glyphosate is concerning. Field experiments were conducted in 2019 and 2020 to evaluate peanut response when exposed at 25, 50, and 75 d after planting (DAP) corresponding to vegetative, flowering, and pod development stages, respectively, to reduced rates of 1/512×, 1/128×, 1/32×, and 1/8× of the labeled rate of 2,4-D plus glyphosate (i.e., 1,077 + 1,132 g ae ha−1, respectively). 2,4-D plus glyphosate was more injurious to peanuts when exposed at 25 DAP compared with 50 and 75 DAP. Similarly, greater canopy height (12%) and canopy width (16%) reductions were observed at 25 DAP compared with 50 and 75 DAP exposure timings (3% to 9%). This result indicates that peanut is more sensitive to 2,4-D plus glyphosate exposure at the vegetative growth stage than at the flowering and pod development stages. However, yield reductions (13% to 16%) were not different between 25, 50, or 75 DAT exposure timings. Regression analysis indicated a linear response for peanut injury, canopy height, width, and yield reduction with an increasing rate of 2,4-D plus glyphosate. The highest rate of 2,4-D plus glyphosate (1/8× of the label rate) resulted in 38%, 22%, and 23% peanut injury, canopy height, and width reduction at 4 wk after treatment, and 33% yield reduction. There was a correlation between peanut injury and yield reduction, with Pearson’s rho values ranging from 0.70 to 0.73. The findings suggest that peanut injury rating data after 2,4-D plus glyphosate drift can be useful for estimating potential yield losses.
Using Citizen Voice to Evaluate Experiments on Politicians: A UK Survey Experiment
Authors: John Peter , Kim Kristina , Soto-Tamayo Luis 
Published: February 2023

AbstractExperiments on the responsiveness of elected officials highlight the tension between the freedom to carry out research and the right of subjects to be treated with respect. Controversy emerges from the power of politicians to block or object to experimental designs using identity deception. One way to resolve this conundrum is to consult citizens who, as constituents of politicians, have an interest in promoting the accountability of elected representatives. Building on the work of Desposato and Naurin and Öhberg, this survey experiment presented research designs to UK citizens for their evaluation. The findings show that citizens strongly approve of experimental research on Members of Parliament (MPs) and are glad to see their representatives participate. There are no differences in support whether designs use identity deception, debriefing, confederates or pre-agreement from MPs. Linked to high interest in politics, more citizens are glad their MPs participate in studies using identity deception than those deploying confederates.
M2‐SCREAM: A Stratospheric Composition Reanalysis of Aura MLS Data With MERRA‐2 Transport
Authors: Wargan Krzysztof , Weir Brad , Manney Gloria L. , Cohn Stephen E. , Knowland K. Emma , Wales Pamela A. , Livesey Nathaniel J. 
Published: February 2023

AbstractThe MERRA‐2 Stratospheric Composition Reanalysis of Aura Microwave Limb Sounder (M2‐SCREAM) is a new reanalysis of stratospheric ozone, water vapor, hydrogen chloride (HCl), nitric acid (HNO3) and nitrous oxide (N2O) between 2004 and the present (with a latency of several months). The assimilated fields are provided at a 50‐km horizontal resolution and at a three‐hourly frequency. M2‐SCREAM assimilates version 4.2 Microwave Limb Sounder (MLS) profiles of the five constituents alongside total ozone column from the Ozone Monitoring Instrument. Dynamics and tropospheric water vapor are constrained by the MERRA‐2 reanalysis. The assimilated species are in excellent agreement with the MLS observations, except for HNO3in polar night, where data are not assimilated. Comparisons against independent observations show that the reanalysis realistically captures the spatial and temporal variability of all the assimilated constituents. In particular, the standard deviations of the differences between M2‐SCREAM and constituent mixing ratio data from The Atmospheric Chemistry Experiment Fourier Transform Spectrometer are much smaller than the standard deviations of the measured constituents. Evaluation of the reanalysis against aircraft data and balloon‐borne frost point hygrometers indicates faithful representations of small‐scale structures in the assimilated water vapor, HNO3and ozone fields near the tropopause. Comparisons with independent observations and a process‐based analysis of the consistency of the assimilated constituent fields with the MERRA‐2 dynamics and with large‐scale stratospheric processes demonstrate the utility of M2‐SCREAM for scientific studies of chemical and transport variability on time scales ranging from hours to decades. Analysis uncertainties and guidelines for data usage are provided.
The role of tropical waves in the genesis of Tropical Cyclone Seroja in the Maritime Continent
Authors: Latos Beata , Peyrillé Philippe , Lefort Thierry , Baranowski Dariusz B. , Flatau Maria K. , Flatau Piotr J. , Riama Nelly Florida , Permana Donaldi S. , Rydbeck Adam V. , Matthews Adrian J. 
Published: February 2023

AbstractTropical cyclone Seroja was one of the first tropical cyclones to significantly impact Indonesian land, and the strongest one in such close proximity to Timor Island. In April 2021 Seroja brought historic flooding to near-equatorial regions of Indonesia and East Timor, as well as impacting Western Australia. Here we show that the unusual near-equatorial cyclogenesis in close proximity to a land mass was due to “perfect storm” conditions associated with multiple wave interactions. Specifically, this was associated with enhanced equatorial convection on the leading edge of a Madden–Julian Oscillation (MJO) event. Within the MJO, the interaction between a convectively coupled equatorial Rossby wave and two convectively coupled Kelvin waves span up the initial vortex and accelerated cyclogenesis. On average, such favorable atmospheric conditions can occur once per year. These results indicate the potential for increased predictability of tropical cyclones over the Maritime Continent.