bluuebunny/crossref_metadata_2025_split huggingface dataset:
Systematic review and meta‐analysis of cold snare polypectomy and hot snare polypectomy for colorectal polyps
Authors: Niu Chengu , Bapaye Jay , Zhang Jing , Liu Hongli , Zhu Kaiwen , Farooq Umer , Zahid Salman , Chathuranga Dileepa , Okolo Patrick I 
Published: August 2023

AbstractBackground and AimCold snare polypectomy (CSP) has become increasingly utilized to resect colorectal polyps, given its efficacy and safety. This study aims to compare CSP and hot snare polypectomy (HSP) for resecting small (< 10 mm) and large (10–20 mm) colorectal lesions.MethodsRelevant publications were obtained from Cochrane Library, Embase, Google Scholar, PubMed, and Web of Science databases. The publication search was limited by English‐language and human studies. Pooled mean difference and odds ratios (ORs) were calculated for outcomes of interest.ResultsTwenty‐three studies were included in this meta‐analysis. Pooled OR of delayed post‐polypectomy bleeding (DPPB) in the CSP group versus the HSP group was 0.29 (P = 0.0001, I2 = 29%). Subgroup analysis according to lesion size showed a significant reduction in the DPPB rate in lesion sizes 10–20 mm (pooled OR 0.08, P = 0.003, I2 = 0%) and < 10 mm (pooled OR 0.35, P = 0.001, I2 = 27%). Pooled OR of major bleeding in the CSP group was 0.23 (P = 0.0004, I2 = 0%). Subgroup analysis by lesion size revealed a significant decrease in the rate of major bleeding in the CSP group for both lesion sizes 10–20 mm (pooled OR 0.11, P = 0.04) and < 10 mm (pooled OR 0.26, P = 0.003). Complete resection, en bloc resection, and recurrence rate were comparable in the two groups.ConclusionsCold snare polypectomy was associated with a lower rate of DPPB and lower risk of major bleeding compared with HSP in both small and large polyps. CSP should be considered as the polypectomy technique of choice for colorectal polyps.
The role of drought, disturbance, and seed dispersal in dominance shifts in a temperate grassland
Authors: Orbán Ildikó , Ónodi Gábor , Kröel‐Dulay György 
Published: August 2023

AbstractAimsMore intense and frequent droughts predicted for the future will heavily affect grasslands worldwide and, along with various other disturbances, possibly trigger major vegetation shifts. Therefore, documenting these changes and understanding the mechanisms behind them is essential. Our study aimed to investigate how dominant species in a semiarid grassland respond to a combination of small‐scale experimental disturbances and naturally occurring droughts and uncover the underlying mechanisms.LocationCentral Hungary.MethodsWe conducted a small‐scale disturbance experiment in a semiarid temperate grassland and followed recovery for 18 years, including severe drought events. In 1999, we established 16 sites, eight dominated by Festuca vaginata and another eight by Stipa borysthenica, the two dominant species of sand grasslands in the region. At each site, three permanent plots were marked that received either a cutting or digging treatment or remained as controls. We monitored the cover and density changes of Festuca and Stipa annually.ResultsIn the early years following the disturbance, Festuca recovered at a similar rate under both disturbance treatments, while Stipa recovered faster in cut than in dug plots. When natural drought events caused major diebacks of both species, Stipa recovered very quickly and regained dominance in initially Stipa‐dominated plots, and it also took over in initially Festuca‐dominated control and cut plots. However, digging at Festuca‐dominated sites delayed drought‐induced Stipa colonisation and thus favoured Festuca recovery. We found that the poor performance of Stipa in dug plots was related to sharply reduced seedling establishment, which resulted from the low number of seeds captured by the bare soil surface after digging.ConclusionsOur results demonstrate that recurring drought events may induce dominance shifts in temperate grasslands, but small‐scale disturbances can modulate vegetation responses. Our findings emphasise the importance of post‐disturbance regeneration patterns in drought‐induced vegetation shifts and show that seed dispersal strategy may have a major effect on vegetation dynamics.
Basally distributed actin array drives embryonic hypocotyl elongation during the seed‐to‐seedling transition in Arabidopsis
Authors: Cui Xuan , Zou Minxia , Li Jiejie 
Published: August 2023

Summary
Seed germination is a vital developmental transition for the production of progeny by sexual reproduction in spermatophytes. The seed‐to‐seedling transition is predominately driven by hypocotyl cell elongation. However, the mechanism that underlies hypocotyl growth remains largely unknown.
In this study, we characterized the actin array reorganization in embryonic hypocotyl epidermal cells. Live‐cell imaging revealed a basally organized actin array formed during hypocotyl cell elongation. This polarized actin assembly is a barrel‐shaped network, which comprises a backbone of longitudinally aligned actin cables and a fine actin cap linking these cables.
We provide genetic evidence that the basal actin array formation requires formin‐mediated actin polymerization and directional movement of actin filaments powered by myosin XIs. In fh1‐1 and xi3ko mutants, actin filaments failed to reorganize into the basal actin array, and the hypocotyl cell elongation was inhibited compared with wild‐type plants.
Collectively, our work uncovers the molecular mechanisms for basal actin array assembly and demonstrates the connection between actin polarization and hypocotyl elongation during seed‐to‐seedling transition.
Prevention of Bone Cement Displacement in Kümmell Disease without Neurological Deficits through Treatment with a Novel Hollow Pedicle Screw Combined with Kyphoplasty
Authors: Zhong Shixiao , Bao Feilong , Fan Qianbo , Zhao Yayu , Li Weichao 
Published: August 2023

ObjectiveDisplacement of bone cement following percutaneous vertebral augmentation for Kümmell disease (KD) presents a significant concern, resulting in increasing back pain and compromising daily activities. Unfortunately, current literature does not yet establish a validated and minimally invasive surgical intervention for this issue. This study aims to investigate the effects of a novel hollow pedicle screw combined with kyphoplasty (HPS‐KP) in preventing bone cement displacement following simply percutaneous kyphoplasty for the management of KD.MethodsA total of 22 patients (six males, 16 females, averagely aged 77.18 ± 7.63 years) with KD without neurological deficits treated by HPS‐KP at the hospital between March 2021 and June 2022 were hereby selected, among which, there were three stage I KD cases, 12 stage II KD cases, and seven stage III KD cases according to Li's classification. Bone mineral density (BMD), spinal X‐ray, computed tomography (CT), and magnetic resonance imaging (MRI) were examined before the operation. The operation time, intraoperative blood loss, and postoperative complications were all recorded. The follow‐up focused on visual analog scale (VAS) score, Oswestry dysfunction index (ODI), anterior vertebral height (AVH), middle vertebral height (MVH), posterior vertebral height (PVH), wedge‐shape affected vertebral Cobb angle (WCA), and bisegmental Cobb angle (BCA). One‐way analysis of variance (ANOVA) followed by Bonferroni post‐hoc test was employed for performing multiple comparisons in the present study.ResultsAll patients having received the operation successfully were followed up for more than 8 months (ranging from 8 to 18 months). The operation time, intraoperative blood loss, and BMD (T‐score) were 39.09 ± 5.64 min, 14.09 ± 3.98 ml, and − 3.30 ± 0.90 g/cm3, respectively. Statistically significant differences were observed in the VAS score, ODI, AVH, MVH, and WCA (All p < 0.05), but there was no statistically significant difference in PVH and BCA at different time points (All p > 0.05). During follow‐up, five patients suffered from bone cement leakage, and one presented an adjacent vertebral fracture and no bone cement displacement.ConclusionHPS‐KP could be safe and effective in the treatment of KD without neurological deficits, effectively relieving the symptoms of patients, restoring partial vertebral height, and preventing the occurrence of bone cement displacement.
Targeted editing of multiple homologues of GTR1 and GTR2 genes provides the ideal low‐seed, high‐leaf glucosinolate oilseed mustard with uncompromised defence and yield
Authors: Mann Avni , Kumari Juhi , Kumar Roshan , Kumar Pawan , Pradhan Akshay K. , Pental Deepak , Bisht Naveen C. 
Published: August 2023

SummaryGlucosinolate content in the two major oilseed Brassica crops—rapeseed and mustard has been reduced to the globally accepted Canola quality level (<30 μmoles/g of seed dry weight, DW), making the protein‐rich seed meal useful as animal feed. However, the overall lower glucosinolate content in seeds as well as in the other parts of such plants renders them vulnerable to biotic challenges. We report CRISPR/Cas9‐based editing of glucosinolate transporter (GTR) family genes in mustard (Brassica juncea) to develop ideal lines with the desired low seed glucosinolate content (SGC) while maintaining high glucosinolate levels in the other plant parts for uncompromised plant defence. Use of three gRNAs provided highly efficient and precise editing of four BjuGTR1 and six BjuGTR2 homologues leading to a reduction of SGC from 146.09 μmoles/g DW to as low as 6.21 μmoles/g DW. Detailed analysis of the GTR‐edited lines showed higher accumulation and distributional changes of glucosinolates in the foliar parts. However, the changes did not affect the plant defence and yield parameters. When tested against the pathogen Sclerotinia sclerotiorum and generalist pest Spodoptera litura, the GTR‐edited lines displayed a defence response at par or better than that of the wild‐type line. The GTR‐edited lines were equivalent to the wild‐type line for various seed yield and seed quality traits. Our results demonstrate that simultaneous editing of multiple GTR1 and GTR2 homologues in mustard can provide the desired low‐seed, high‐leaf glucosinolate lines with an uncompromised defence and yield.
Intergroup friendship: A reflective spotlight
Authors: Dion Karen K. 
Published: August 2023

AbstractGrowing empirical evidence supports the positive contribution of cross‐group friendship to intergroup attitudes, as well as to individuals' personal development. However, developing cross‐group friendships may be challenging depending on individuals' respective group identities; namely, their ethnicity, gender, race, and sexual orientation identities. This paper considers how psychological factors related to these group identities contribute to cross‐group friendship. Research on individuals' experiences of cross‐group interactions across different contexts (first encounters; interacting with friends) has found that these interactions can be challenging. Most explanations of these challenges have focused either directly or indirectly on issues related to prejudice. It is suggested here that another important but neglected perspective for understanding intergroup friendship concerns individuals' awareness and responsiveness to differences in privileges and opportunities associated with their own and their friend's group‐related identities. The implications are discussed in the context of friendship values and relationship qualities in intergroup friendship.
Evaluation of different antimicrobial agents for laboratory and field against Pantoea agglomerans, the causative agent of bacterial leaf blight disease on oat (Avena sativa)
Authors: Wang Jianjun , Chen Taixiang , Wei Xuekai , Kamran Malik , White James F. , Zhao Guiqin , Li Chunjie 
Published: August 2023

AbstractLeaf blight disease (LBD) caused by Pantoea agglomerans is a newly emerged oat disease in China that causes great economic and yield losses of oat production. Laboratory and field experiments were conducted to evaluate the efficacy of 13 antimicrobial agents against P. agglomerans and recommend agents with better control efficacy for use. The antibacterial potential of four concentrations of each agent was evaluated under in vitro conditions. Zhongshengmycin and ethylicin were the most effective in inhibiting the growth of P. agglomerans; their bacteriostatic rates (85.0% and 84.8%, respectively) were higher while EC50 lower (0.31 and 0.90, respectively) than other agents. The greenhouse and field experiment suggested that the greatest fresh weight per plant (57.26 g and 57.93 g), forage yield (22.53 t/ha and 22.21 t/ha) and control efficacy (>75%) were obtained after spraying twice with zhongshengmycin or ethylicin in the LBD occurrence phase, with lower yields and control by kasugamycin + dicopper chloride trihydroxide, kasugamycin + oxine copper, benziothiazolinone, copper hydroxide, phenanthrenecarboxylicacid, copper, picoxystrobin, chloroisobromine cyanuric acid, oxathiapiprolin or azoxystrobin. Foliar application of zhongshengmycin or ethylicin can therefore be used for the effective management of LBD of oat.
Evaluating the prerequisites for adapting a paediatric nighttime telemedicine and medication delivery service to a setting with high malarial burden: A cross‐sectional pre‐implementation study
Authors: Flaherty Katelyn E. , Klarman Molly B. , Zakariah Ahmed N. , Mahama Mohammed‐Najeeb , Osei‐Ampofo Maxwell , Nelson Eric J. , Becker Torben K. 
Published: August 2023

AbstractObjectiveWe sought to evaluate the prerequisites (demand, interest, feasibility) for adapting a paediatric nighttime telemedicine and medication delivery service (TMDS) to Ghana.MethodsA cross‐sectional survey of households and associated healthcare providers was conducted in urban and rural Ghana. Households were identified through randomised geospatial sampling; households with at least one child <10 years were enrolled. Household surveys collected information relating to demographics, household resources, standardised case scenarios, recent paediatric health events, satisfaction with healthcare access, and interest in TMDS intervention models. Providers were identified by households and enrolled. Provider surveys collected provider type, hours of operation, services, and opinions of a TMDS model.ResultsA total of 511 (263 urban, 248 rural) households and 18 providers (10 urban, 8 rural) were surveyed. A total of 262 health events involving children <10 years were reported, of which 47% occurred at night. Care was sought for >70% of health events presenting at night; however, care‐seeking was delayed until morning or later for >75% of these events; 54% of households expressed dissatisfaction with their current access to paediatric care at night; 99% of households expressed that a nighttime TMDS service for children would be directly useful to their families. Correspondingly, 17 of 18 providers stated that a TMDS was needed in their community; >99% of households had access to a cellular phone. All households expressed willingness to use their phones to call a TMDS and allow a TMDS provider into their homes at night. Willingness to pay and provider‐recommended price points varied by setting.ConclusionsPrerequisites for adapting a TMDS to Ghana were met. A nighttime paediatric TMDS service was found to be needed, appealing, and feasible in Ghana. These data motivate the adaptation of a TMDS to urban and rural Ghana.
Longitudinal evaluation of fentanyl concentrations in equine plasma and synovial fluid following application of transdermal fentanyl patches over one carpal joint
Authors: Ortega McCormack John J. , Reed Rachel A. , Epstein Kira L. , Camus Melinda S. , Knych Heather K. 
Published: August 2023

AbstractObjectiveTo determine if transdermally delivered fentanyl can achieve greater concentrations of fentanyl in synovial fluid when applied over a synovial structure.Study designRandomized, experimental study.AnimalsSix healthy adult horses.MethodsEach horse had two 100 μg/h fentanyl matrix patches applied on the dorsal aspect of one, randomly assigned, carpometacarpal joint (CMCJ) for 48 h. Whole blood and bilateral synovial samples from the intercarpal joint were obtained at 0, 2, 6, 12, 24, 36 and 48 h. Fentanyl concentrations were measured with liquid chromatography–mass spectrometry.ResultsAll subjects achieved detectable concentrations of fentanyl in both plasma and synovial fluid. Time to peak synovial and plasma concentration was 12 h. At 6 h, the synovial concentration in the untreated carpus (0.104 ng/mL ± 0.106) was lower than plasma fentanyl concentrations 0.31 ± 0.27 (p = .036). At 12 h, both treated (0.55 ng/mL ± 0.3) and untreated (0.53 ng/mL ± 0.28) synovial fluid fentanyl concentrations were lower than plasma (0.87 ng/mL ± 0.48) concentrations (p < .001 andp = .001, respectively). Synovial concentrations of fentanyl did not differ between treated and untreated joints (p> 0.608 for all time points).ConclusionApplication of fentanyl matrix patches directly over the CMCJ did not result in increased fentanyl concentrations in the synovial fluid of the treated intercarpal joint in normal horses.Clinical significanceThere is likely no analgesic advantage to placing fentanyl patches directly over the affected joint, as it did not result in increased synovial concentrations at the tested site.
Near‐infrared fluorescence cholangiography in dogs: A pilot study
Authors: Larose Philippe Chagnon , Brisson Brigitte A. , Sanchez Andrea , Monteith Gabrielle , Singh Ameet , Zhang Michael 
Published: August 2023

AbstractObjectiveTo determine the effect of indocyanine green (ICG) dose and timing of administration on near‐infrared fluorescence (NIRF) imaging of the normal canine biliary tree.Study designPreclinical prospective study.AnimalsEight purpose‐bred beagles.MethodsThe dogs were randomized to receive two of four intravenous ICG dose (low [L]:0.05 mg/kg or high [H]:0.25 mg/kg)/time (0 and 3 h prior to NIRF) combinations. NIRF images were collected every 10 min for 120 min. Target (cystic duct)‐to‐background (liver) ratios were calculated for all timepoints and compared.ResultsICG cholangiography was successful in all dogs. The contrast ratio was above 1 in the L0 group by 20 min and reached its peak at 100 min. In the H0 group, the ratio was above 1 by 60 min and reached its peak at 90 min. Contrast ratios above 2 (fluorescence twice as bright in the cystic duct compared to the liver) were maintained from 180 to 300 min for L3 and H3 and was achieved after 80 min for L0.ConclusionLow dose ICG provided better ratios early after injection compared to the high dose which remained highly concentrated in the liver tissue after injection. Both doses provided excellent visualization of the biliary tree at 3 h post injection, low dose ICG provided better ratios from 3 to 5 h post injection. Based on these results, 0.05 mg/kg of ICG administered at anesthetic premedication, or as early as 3 h prior to laparoscopic surgery should yield optimal fluorescence images.Clinical significanceThis study provides guidelines for NIRF cholangiography in clinically normal dogs.
Modeling and Experimental Validation of CFRP–Metal Joints Utilizing 3D Additively Manufactured Anchors
Authors: De Pasquale Giorgio , Coluccia Antonio 
Published: August 2023

Abstract
The joining techniques between carbon fiber reinforced polymer (CFRP) and metal are of great importance in many areas of structural mechanics where the optimization of weight, rigidity, and strength is a necessity (such as aeronautics, vehicles, energy generation, and biomechanics). As a result, several types of metal–composite joints have been manufactured using different methods, with the 3D metal anchor solution attracting significant attention. This study evaluates different anchor geometries applied to single lap joints through preliminary finite element method (FEM) simulations and experimental validation on joints between CFRP and Inconel 625 produced via a laser beam powder bed fusion (LB-PBF) additive process. The models proposed increase in complexity. The homogenization process is employed to determine the equivalent properties of the joint region that is occupied by metal anchors and CFRP. The model also supports topology parametrization to assess the impact of anchor geometry on structural properties. The study provides experimental validation of joint strength under tensile load for various anchoring surface topologies.
The Role of Fracture Patterns on Crack-Based Strain Sensors
Authors: Zhao Huan , Liu Xiangbei , Li Yan 
Published: August 2023

Abstract
Crack-based strain sensors (CBS), which are inspired by a spider's slit organ, can provide highly sensitive measurement with great flexibility. Fracture pattern design holds the key to meeting different sensing needs. In this article, a computational model is developed to understand the role of fracture patterns on sensitivity and sensing range of CBS that consist of a platinum (Pt) conductive layer and a polydimethylsiloxane (PDMS) substrate layer. Through the coupled mechanical–electrical finite element analysis, we find that a single mode I through crack can yield better sensing performance than a nonthrough crack in other orientations or a few discrete nonthrough cracks in the same orientation. Creating multiple mode I through cracks has a negligible effect on sensitivity. However, increasing the number of cracks can lead to a higher sensing range. When the same number of cracks is employed, even crack spacing can yield the highest sensing range. Sensitivity can be effectively improved by increasing the crack depth. Conclusions from the computational analysis can provide useful feedback for design and manufacturing of CBS in different applications.
De novo
genome sequence of endophytic biocontrol strain
Bacillus
sp. ST24 isolated from rice seed
Authors: Khanal Sabin , Antony-Babu Sanjay , Zhou Xin-Gen 
Published: August 2023

ABSTRACT

In this study, we present the genome sequence of
Bacillus
sp. strain ST24, an endophytic bacterium isolated from rice seeds. The genome assembly comprises a total of 5,799,877 bp, with a GC content of 34.81%. Furthermore, our analysis revealed the presence of various genes associated with antibiotic production, as well as genes involved in polyketide biosynthesis and non-ribosomal polyketide-like clusters.
Genomes of two type strains of the
Rhizobium tropici
group:
R. calliandrae
CCGE524
T
and
R. mayense
CCGE526
T
Authors: Moura Fernanda Terezinha , Helene Luisa Caroline Ferraz , Klepa Milena Serenato , Ribeiro Renan Augusto , Nogueira Marco Antonio , Hungria Mariangela 
Published: August 2023

ABSTRACT

The genome sequences of two nitrogen-fixing type strains of the
Rhizobium tropici
group were obtained:
Rhizobium calliandrae
CCGE524
T
and
R. mayense
CCGE526
T
. Genomic analyses confirmed their taxonomic position and identified three complete sequences of the
repABC
genes, indicative of three plasmids, one of them carrying symbiotic genes.