bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development and Validation a nomogram to predict the risk of pulmonary metastasis in pediatric osteosarcoma
Authors: ouyang haiping , Wang Jinkui , Wang Zhongliang 
Published: January 2023

Abstract
Background
Most malignant bone tumors in children and adolescents are osteosarcomas. Pediatric osteosarcoma has a high mortality rate due to pulmonary metastasis, which occurs in a short period of time. We would like to establish a nomogram to predict the risk of pulmonary metastasis of pediatric osteosarcoma to help doctors conduct early intervention and and improve their survival rate.
Methods
The clinicopathological information of patients was downloaded from SEER to identify pediatric osteosarcoma from 2004 to 2018. We analyzed the independent risk factors for pulmonary metastasis of pediatric osteosarcoma in the training cohort using univariate and multivariate logistic regression. Using these risk factors, we established a Nomogram prediction for pulmonary metastasis of pediatric osteosarcoma. We used three indicators to evaluate the accuracy of the nomogram. These three were calibration curve, c-index and area under the receiver operating curve (AUC). The clinical value of this nomogram was evaluated using Decision curve analysis (DCA).
Results
A sum of 1362 pediatric patients with osteosarcoma were involved in this research. They were randomly divided into the training cohort (N = 965) and the validation cohort (N = 397). In training cohort, univariate and multivariate logistic regression analysis showed that there were four independent risk factors, namely T stage, N stage, surgery, and radiotherapy. We constructed a new Nomogram to predict the risk of pulmonary metastasis in pediatric osteosarcoma. In the training cohorts and validation cohorts, the C-index was 0.699 (95% CI, 0.656–0.741) and 0.736 (95% CI, 0.675–0.797),respectively, indicating that the nomogram had good accuracy. The AUC of training group and validation group showed good predictive ability.
Conclusion
This study constructed a new nomogram to predict the risk of pulmonary metastasis in pediatric osteosarcoma. Our nomogram can help doctors provide accurate assessment of individual risk, active monitoring and follow-up of patients, and prevent pulmonary metastasis in pediatric osteosarcoma.
Microfacial Analyses on the Building Stones of the Maya Site of Calakmul
Authors: García-Solís Claudia Araceli , Quintana-Owen Patricia , López-Doncel Rubén Alfonso , Illescas-Salinas Juan Francisco 
Published: January 2023

Abstract
This article focuses on the petrographic and microfacial characterization of the building stones, buildings, monuments, and quarries of the archeological site of Calakmul to document aspects of composition, lithologies, and stone exploitation. Microfacial analysis shows that the used building rocks are highly recrystallized biosparudites (grainstones to packstones) with the presence of reef and shallow waters fauna (boundstones). These rocks have an intermediate porosity (10–20% pore volume values) and XRD analysis confirms that the mineral composition is mainly calcite, but also dolomite. Microfacies analysis demonstrate that limestone of the stelae and the SubIIc-1 main façade come from the same quarry and have fine texture corroborate that these stones are suitable materials for carving and lime production. Samples from St. XX Gran Acropolis and from Chan Chi’ich Group come from a different quarry. These results help us to know the origin of the rocks, their use in the different buildings and monuments studied, and to contribute to the knowledge of their lithological characteristics and their response to weathering and thus provide important information that will help in taking decisions in case of probable measures of restoration and conservation of the rocks in the Calakmul region.
Frailty among Community Dwelling Older Adults: Prevalence and Associated Factors
Authors: Ali Sageda Magdy , AbdElhameed Soad Hassan , Mohamed Doaa 
Published: January 2023

Abstract
Background: Frailty is an important and a highly prevalent health problem in older adults that has a negative impact on health related outcomes. The importance of studying frailty comes from the fact that its merely associated with aging but not an inevitable process.
Aim: To assess prevalence of frailty and its associated factors among community-dwelling older adults.
Method: A community based cross sectional study was used withcluster sampling technique targeted 300 older adults in six urban and rural regions affiliated to Dakahlia governorate. Data was collected using, Mini-mental State Examination, demographic and health-related data structured interview questionnaire, Katz and Akpom scale, Lawton and Brody scale, the Mini Nutritional Asses sment questionnaire and Frailty was measured using survey of health, and aging, and retirement in Europe of the frailty indicator.
Results: Prevalence of frailty was 64.7% among the studied older adults, and only 5.3% were non frail. Age, current work, comorbidity, polypharmavy, IADL, and malnutrition were significant independent predictors for frailty (β 0.136, -0.148, 0.117, 0.118, -0.209, and 0.401 respectively), p < 0.05 for all, and responsible for 72.4% of frailty (R2 = .724).
Conclusion: It can be concluded that frailty was highly prevalent in community-dwellers in Egypt urban and rural regions. Risk factors of frailty include female gender, widohood, illiteracy, living arrangements, previous hospitalization, drug compliance, periodic checkup, engagement into social practices, and smoking. Moreover Older adults' age, work status, income, comorbidities, polypharmacy, functional status, and nutritional status were found as the main factors associated with frailty.
Recommendations: Assessment of associated risk factors of frailty in older adults should be done through community-based healthcare programs for early diagnosis and management.
An Unexpected Settler in the Right Ventricular Outflow Tract in Pulmonary artery sarcoma
Authors: Ahmad Akhlaq 
Published: January 2023

Abstract
Pulmonary artery sarcoma (PAS) is a sporadic malignant tumor that mainly originates from the pulmonary arteries. However, PAS may also involve the right ventricular outflow tract, which may lead to obstruction, syncope, or sudden death. Early diagnosis is essential to prolonging survival and improving the quality of life. Herein, we report a case of a young female patient admitted for pulmonary malignancy and acute pulmonary embolism. The patient had a mass in her right ventricular outflow tract, which was detected by transthoracic echocardiography. Computed tomography and magnetic resonance imaging revealed the invasion depth and extent of the lesions. Surgical resection improved hemodynamics, and pathological and immunohistochemical tests confirmed the diagnosis of a pulmonary artery sarcoma. Local recurrence was detected in the adjacent tissues several months after the surgery. Given the potential risk of reoperation, the patient was suggested to undergo conservative treatment.
MFRRI:Research on multi-feature joint recommendation algorithm based on graph neural network
Authors: Simon Bastien , Joliat Daniel , Weber Erik , Rayment Andrea 
Published: January 2023

Abstract
With the rapid development of Internet technology and the comprehensive popularity of Internet applications, online activities have gradually become an indispensable part of people's daily life. Internet activities are becoming an indispensable part of people's daily life. How to help users quickly find valuable information from the huge amount of data has become a great challenge for the Internet industry. The traditional recommendation system based on collaborative filtering can take advantage of big data because it can well find users with the most similar interests and recommend the items they are interested in, showing a good recommendation effect and has been the main direction of recommendation algorithm research. In recommender systems, most of the information has a graph structure, and the graph neural network GNN technique can capture the relevance of graphs through message passing between graph nodes, so GNNs are often used to generate embedded representations of users/items. However, traditional GNN-based recommendation algorithms are only able to handle regular topological graphs composed of a single type of node, while the data in the current network is not composed of only a single type of node. the main content of this paper is the GNN-based knowledge graph recommendation model. The model can effectively capture the potential interest of users through the user relationship graph for the recommendation. A joint multi-feature representation method is proposed. For user-item interaction, the representation of node features in the case of sparse network connectivity is enhanced by using multi-order topological structure information in information networks. The model in this paper was verified to perform significantly better than the baseline approach by conducting experiments on public datasets.
REVITALIZAÇÃO DO NÚCLEO DE ESTUDOS EM GESTÃO E NEGÓCIOS POR MEIO DO PROJETO OXIGÊNIO
Authors: Régis Oliveira Alysson André , Silva dos Santos Allisson , Oliveira Domingos Geizyellen , Araújo Feitosa de Oliveira Aline 
Published: January 2023

Desde sua constituição, em 2017, o Núcleo de Estudos em Gestão e Negócios (NEGN) perpassa por uma rotatividade de atores, principalmente de estudantes. Este trabalho teve por objetivo fortalecer a identidade do NEGN da Rede Rizoma, potencializando suas práticas extensionistas. O plano metodológico foi dividido em cinco etapas, sendo elas: (a) levantamento e atualização dos integrantes do Núcleo; (b) reunião de apresentação do núcleo para os novos integrantes; (c) atuação junto à comunidade local, (d) planejamento do NEGN e (e) atuação de algumas frentes de trabalho nas vertentes das práticas extensionistas. Foi perceptível uma mudança nos eixos da vida profissional e acadêmica dos seus participantes, trazendo a prática do curso de Administração para a realidade deles.

Palavras-chave: núcleo de estudos; gestão e negócios; revitalização.
A IMPORTÂNCIA DA INSERÇÃO DE ATIVIDADES DE EXTENSÃO UNIVERSITÁRIA PARA O DESENVOLVIMENTO PROFISSIONAL
Authors: Pinheiro Jonison Vieira , Silva Narciso Christian 
Published: January 2023

As atividades extensionistas em junção com as atividades de ensino e pesquisa, assumem um papel de extrema importância na construção e articulação de ideias e envolvimento da sociedade/comunidade ao qual a instituição de ensino está inserida, é definida por alguns autores como uma via de mão-dupla, pois possibilita a troca de saberes acadêmicos e populares. Este trabalho aborda conceitos e momentos históricos que marcaram a criação e aplicabilidade das atividades de extensão universitária. Por meio de uma análise sistemática na literatura e obedecendo ao objetivo principal desta pesquisa, este trabalho apresenta a importância das atividades de extensão para discentes, docentes e comunidade, e como esta contribui para o desenvolvimento profissional dos envolvidos.
Palavras-Chave: Atividades extensionistas; Universidade e Sociedade; Ensino e Pesquisa.
AÇÕES EXTENSIONISTAS EM TEMPOS DE ADVERSIDADE
Authors: GURGEL PIRES ELOIZA , Couto Caio 
Published: January 2023

Na tentativa de discutir a importância das ações extensionistas universitárias e as suas relações com os campos da Arte e da Cultura, especialmente no contexto de pandemia global ocasionado pela Covid-19 nos últimos dois anos – 2020 e 2021 –, este artigo apresenta uma reflexão sobre a experiência do Coletivo Identidade Visual, grupo vinculado ao projeto de extensão Arte, Educação e Cultura Visual: interconexões, práticas e reflexões – FFP/UERJ .
Palavras chaves: Extensão universitária, arte e cultura visual, pandemia.
Electrospun Polymer Nanofibers for Technology Applications: A Short
Review
Authors: Pathak Dinesh , Sharma Ankush , Sharma Rajesh Kumar , Nunzi J.M. , Mahajan Aman , Sharma Davinder Pal 
Published: January 2023

Abstract:
Nanofibers are a type of nanomaterial with a diameter ranging from ten to a few hundred nanometers with a high surface-to-volume ratio and porosity. They can build a network of high-porosity material with excellent connectivity within the pores, making them a preferred option for numerous applications. This review explores nanofibers from the synthesis techniques to fabricate nanofibers, with an emphasis on the technological applications of nanofibers like water and air filtration, photovoltaics, batteries and fuel cells, gas sensing, photocatalysis, and biomedical applications like wound dressing and drug delivery. The nanofiber production market has an expected compound annual growth rate (CAGR) of 6% and should reach around 26 million US $ in 2026. The limitations and potential opportunities for large-scale applications of nano-fibrous membranes are also discussed. We expect this review could provide enriched information to better understand Electrospun Polymer Nanofiber Technology and recent advances in this field.
Examining Recruitment Strategies in the Enrollment Cascade of Youth Living With HIV: Descriptive Findings From a Nationwide Web-Based Adherence Protocol
Authors: Gurung Sitaji , Jones Stephen Scott , Mehta Kripa , Budhwani Henna , MacDonell Karen , Belzer Marvin , Naar Sylvie 
Published: January 2023

Background
Digital strategies and broadened eligibility criteria may optimize the enrollment of youth living with HIV in mobile health adaptive interventions. Prior research suggests that digital recruitment strategies are more efficient than traditional methods for overcoming enrollment challenges of youth living with HIV in the United States.

Objective
This study highlights the challenges and strategies that explain screening and enrollment milestones in a national web-based adherence protocol for youth living with HIV.

Methods
Baseline data from a national web-based HIV adherence protocol for youth living with HIV, collected from July 2018 to February 2021, were analyzed. A centralized recruitment procedure was developed, which used web-based recruitment via Online Master Screener; paid targeted advertisements on social media platforms (eg, Facebook and Reddit) and geosocial networking dating apps (eg, Grindr and Jack’d); and site and provider referrals from Subject Recruitment Venues and other AIDS service organizations, website referrals, and text-in recruitment.

Results
A total of 3 distinct cohorts of youth living with HIV were identified, marked by changes in recruitment strategies. Overall, 3270 individuals consented to screening, 2721 completed screening, 581 were eligible, and 83 completed enrollment. We examined sociodemographic and behavioral differences in completing milestones from eligibility to full enrollment (ie, submitting antiretroviral therapy and viral load data and completing the baseline web-based survey). Those with the most recent viral load tests >6 months ago were half as likely to enroll (odds ratio 0.45, 95% CI 0.21-0.94). Moreover, eligible participants with self-reported antiretroviral therapy adherence (SRA) between 50% and 80% were statistically significant (P<.001 to P=.03) and more likely to enroll than those with SRA >80%.

Conclusions
The findings add to our knowledge on the use of digital technologies for youth living with HIV before and during the COVID-19 pandemic and provide insight into the impact of expanding eligibility criteria on enrollment. As the COVID-19 pandemic continues and the use of and engagement with social media and dating apps among youth living with HIV changes, these platforms should continue to be investigated as potential recruitment tools. Using a wide variety of recruitment strategies such as using social media and dating apps as well as provider referral mechanisms, increasing compensation amounts, and including SRA in enrollment criteria should continue to be studied with respect to their ability to successfully recruit and enroll eligible participants.

International Registered Report Identifier (IRRID)
RR2-10.2196/11183
Feasibility and Acceptability of Wearable Cameras to Assess Self-care in People With Heart Failure: Pilot Study
Authors: Askman Sanna , Löf Marie , Maddison Ralph , Nourse Rebecca 
Published: January 2023

Background
Heart failure (HF) is a common chronic condition that affects over 26 million people worldwide. It is a progressive and debilitating disease with a broad symptom profile, intermittently marked by periods of acute decompensation. People with HF generally do not self-manage their condition well (eg, monitoring symptoms, taking medications regularly, physical activity, etc). A better understanding of self-care activities and what factors may indicate deterioration is warranted.

Objective
The aim of this study was to determine the feasibility and acceptability of using wearable cameras to assess self-care activities in people with HF. The study objectives were to (1) explore whether changes in self-care activities could be identified prior to hospitalization and (2) determine the acceptability of wearable cameras to people with HF.

Methods
A total of 30 people recently diagnosed with HF wore a camera for a maximum of 30 days; the camera took a photo every 30 seconds in the forward-facing direction. At the end of the study, all 30 participants were presented with 8 statements of acceptability, scored on a 5-point Likert scale. To determine whether camera images could identify changes in self-care activities and lifestyle risk factors before hospitalization, we analyzed images from participants (n=8) who were hospitalized during the 30-day study period. Images from the period immediately prior to hospitalization and a comparison were selected for each participant. Images were manually coded according to 9 different event categories relating to self-care and lifestyle risk factors, and events were compared between the 2 periods.

Results
The participants reported high acceptability for wearing the cameras, as most strongly agreed or agreed that they were comfortable to wear (28/30, 93%) and easy to use (30/30, 100%). The results of the camera image analysis showed that participants undertook fewer activities of daily living (P=.008) and were more sedentary (P=.02) prior to being hospitalized, compared to a period nonadjacent to hospitalization.

Conclusions
Adults with HF were accepting of using a wearable camera for periods within a 30-day time frame. Wearable cameras were a feasible approach for providing data on selected self-care activities and lifestyle risk factors for HF and offer the potential to be a valuable tool for improving our understanding of self-care.
User Engagement and Weight Loss Facilitated by a Mobile App: Retrospective Review of Medical Records
Authors: Valinskas Sarunas , Nakrys Marius , Aleknavičius Kasparas , Jonusas Justinas , Lileikienė Angelė 
Published: January 2023

Background
Intermittent fasting (IF) has gained popularity in recent years for its effect on weight loss and supposed additional health benefits, such as a positive effect on body composition and metabolic markers. Mobile apps can act as platforms that help deliver dietary interventions by improving adherence and motivation. Although the effect of IF on weight loss has been demonstrated in earlier trials, there is not much research about the engagement and weight loss results with IF apps.

Objective
Our main objective was to compare how a nudging platform (including smart scales) influences engagement (the extent to which users interact with the app measured by the number of active days) with the app among users who had obesity at the beginning of use. The secondary objectives were to evaluate the body weight changes among active and nonactive users and, finally, to evaluate the body composition changes of users possessing smart scales during app usage. Through this study, we hope to provide (1) more insight into how nudging (using smart scales as a nudging platform) is associated with engagement with the mobile app, (2) how engagement with the mobile app is associated with weight loss, and (3) how IF is associated with body composition.

Methods
We performed a retrospective analysis of data from 665 users with obesity (BMI≥30) who started using the IF app DoFasting. Of them, 244 used body composition scales that estimated body fat and body muscle values. Users were stratified into engagement groups in accordance with their activity ratio (number of active days divided by the total time of use). Baseline and final users' weight (in kg), body fat (in %), and body muscle (in %) were compared.

Results
Our findings suggest an association between the nudging platform (smart scales) and better engagement with the app. Smart scale users had a significantly higher activity ratio than regular users. Additionally, active DoFasting users lost significantly more weight. Further, body composition analysis showed that app usage might be related to body fat loss and an increase in muscle mass.

Conclusions
We found a possible association between the nudging and gamified elements and higher app engagement. Additionally, increased app engagement is associated with increased weight loss. Thus, nudging and gamified elements of mobile health apps, such as interactive tools, goals, challenges, and progress tracking, are suggested to affect engagement positively and should be investigated further in future research. Finally, the IF regime delivered through the DoFasting app might be related to the body muscle mass gain and reduced fat mass.
The Effect of the COVID-19 Pandemic on Digital Health–Seeking Behavior: Big Data Interrupted Time-Series Analysis of Google Trends
Authors: van Kessel Robin , Kyriopoulos Ilias , Wong Brian Li Han , Mossialos Elias 
Published: January 2023

Background
Due to the emergency responses early in the COVID-19 pandemic, the use of digital health in health care increased abruptly. However, it remains unclear whether this introduction was sustained in the long term, especially with patients being able to decide between digital and traditional health services once the latter regained their functionality throughout the COVID-19 pandemic.

Objective
We aim to understand how the public interest in digital health changed as proxy for digital health–seeking behavior and to what extent this change was sustainable over time.

Methods
We used an interrupted time-series analysis of Google Trends data with break points on March 11, 2020 (declaration of COVID-19 as a pandemic by the World Health Organization), and December 20, 2020 (the announcement of the first COVID-19 vaccines). Nationally representative time-series data from February 2019 to August 2021 were extracted from Google Trends for 6 countries with English as their dominant language: Canada, the United States, the United Kingdom, New Zealand, Australia, and Ireland. We measured the changes in relative search volumes of the keywords online doctor, telehealth, online health, telemedicine, and health app. In doing so, we capture the prepandemic trend, the immediate change due to the announcement of COVID-19 being a pandemic, and the gradual change after the announcement.

Results
Digital health search volumes immediately increased in all countries under study after the announcement of COVID-19 being a pandemic. There was some variation in what keywords were used per country. However, searches declined after this immediate spike, sometimes reverting to prepandemic levels. The announcement of COVID-19 vaccines did not consistently impact digital health search volumes in the countries under study. The exception is the search volume of health app, which was observed as either being stable or gradually increasing during the pandemic.

Conclusions
Our findings suggest that the increased public interest in digital health associated with the pandemic did not sustain, alluding to remaining structural barriers. Further building of digital health capacity and developing robust digital health governance frameworks remain crucial to facilitating sustainable digital health transformation.