bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of deep eutectic solvent–based microwave‐assisted extraction combined with temperature controlled ionic liquid–based liquid phase microextraction for extraction of aflatoxins from cheese samples
Authors: Kaboodi Aso , Mirzaei Hamid , Katiraee Farzad , Javadi Afshin , Afshar Mogaddam Mohammad Reza 
Published: July 2023

In this study, for the first time, a deep eutectic solvent‐based microwave‐assisted extraction was combined with ionic liquid–based temperature controlled liquid phase microextraction for the extraction of several aflatoxins from cheese samples. Briefly, the analytes are extracted from cheese sample (3 g) into a mixture of 1.5 mL choline chloride:ethylene glycol deep eutectic solvent and 3.5 mL deionized water by exposing to microwave irradiations for 60 s at 180 W. The liquid phase was taken and mixed with 55 μL 1‐hexyl‐3‐methylimidazolium hexafluorophosphate. By cooling the solution in the refrigerator centrifuge, a turbid state was obtained and the analytes were extracted into the ionic liquid droplets. The analytes were determined by high‐performance liquid chromatography equipped with fluorescence detector. Low limits of detection (9–23 ng kg–1) and quantification (30–77 ng kg–1), high extraction recovery (66%–83%), acceptable enrichment factor (40–50), and good precision (relative standard deviations ≤ 5.2%) were obtained using the offered approach. These results reveal the high extraction capability of the method for determination of aflatoxins in the cheese samples. In this method, there was no need for organic solvents and it can be considered as green extraction method.
Cutaneous leukocytoclastic vasculitis following COVID‐19 vaccination
Authors: Zoppi Manuel , Gandara Victoria , Zoppi Jorge 
Published: July 2023

AbstractAlthough vaccination against COVID‐19 has been proven generally safe, rare but potentially serious adverse reactions do occur. Cutaneous leukocytoclastic vasculitis is the vasculitis of small vessels. We reported two patients with leukocytoclastic vasculitis who were vaccinated with the ChAdOx1‐S/nCoV‐19 and mRNA‐1273. Both cases were confirmed with a skin biopsy. There was a complete recovery with corticosteroids and both were followed up without any recurrence.
Nasal Packing Materials and Placement Duration on Wound Healing in Nasal Mucosa: An Animal Study
Authors: Tochigi Kosuke , Ebihara Teru , Omura Kazuhiro , Aoki Satoshi , Takeda Teppei , Otori Nobuyoshi , Tanaka Yasuhiro 
Published: July 2023

ObjectiveThe histological findings of wound healing depending on different nasal packing materials and replacement periods were lacking.MethodsMucosal defects were created in the nasal septum of rabbits and covered with Spongel®, Algoderm®, or Nasopore®, which were cleaned on Day 14. To investigate the effect of replacement durations, Spongel® was removed on Days 3 and 7. All nasal septal specimens were collected on Day 28. Samples without packing material were prepared as controls. Depending on residual packing materials in the regenerated tissue, specimens were classified into the remnant and non‐remnant groups, and morphology was compared using epithelium grade score and subepithelial thickness.ResultsThe epithelium grade score in the Spongel‐14d group was lower than that in the other groups (p < 0.05). Subepithelial thickness was higher in the Algoderm‐14d and Spongel‐14d groups (p < 0.05). Epithelium grade scores were higher and subepithelial thicknesses were lower in the Spongel‐3d and ‐7d groups than in the Spongel‐14d group. Epithelium grade score was lower and subepithelial thickness was higher in the remnant group (n = 10) than in the non‐remnant group (n = 15; p < 0.05).ConclusionsDifferences in packing materials and placement durations affected wound healing of nasal mucosa. The selection of appropriate packing materials and replacement duration was considered essential for ideal wound healing.Level of EvidenceNA Laryngoscope, 134:562–568, 2024
Calderón–Zygmund theory in Lorentz mixed‐norm spaces and its application to compressible fluids
Authors: Wei Wei , Wang Yanqing , Ye Yulin 
Published: July 2023

AbstractIn this paper, it is shown that the general Calderón–Zygmund singular integral operators including Riesz transforms are bounded on anisotropic Lorentz spaces with and . As an application, we establish some new blowup criteria involving temperature in its scaling‐invariant anisotropic Lorentz space for the 3D full compressible Navier–Stokes equations allowing vacuum and without additional conditions on viscosity coefficients except physical restrictions, which improve the previous corresponding results.
Development of a quasi‐3D dosimeter using radiochromic plastic for patient‐specific quality assurance
Authors: Cho Jin Dong , Jin Hyeongmin , Jung Seongmoon , Son Jaeman , Choi Chang Heon , Park Jong Min , Kim Jin Sung , Kim Jung‐in 
Published: July 2023

AbstractBackgroundPatient‐specific QA verification ensures patient safety and treatment by verifying radiation delivery and dose calculations in treatment plans for errors. However, a two‐dimensional (2D) dose distribution is insufficient for detecting information on the three‐dimensional (3D) dose delivered to the patient. In addition, 3D radiochromic plastic dosimeters (RPDs) such as PRESAGE® represent the volume effect in which the dosimeters have different sensitivities according to the size of the dosimeters. Therefore, to solve the volume effect, a Quasi‐3D dosimetry system was proposed to perform patient‐specific QA using predetermined‐sized and multiple RPDs.PurposeFor patient‐specific quality assurance (QA) in radiation treatment, this study aims to assess a quasi‐3D dosimetry system using an RPD.MethodsGamma analysis was performed to verify the agreement between the measured and estimated dose distributions of intensity‐modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT). We fabricated cylindrical RPDs and a quasi‐3D dosimetry phantom. A practicability test for a pancreatic patient utilized a quasi‐3D dosimetry device, an in‐house RPD, and a quasi‐3D phantom. The dose distribution of the VMAT design dictated the placement of nine RPDs. Moreover, a 2D diode array detector was used for 2D gamma analysis (MapCHECK2). The patient‐specific QA was performed for IMRT, VMAT, and stereotactic ablative radiotherapy (SABR) in 20 prostate and head‐and‐neck patients. For each patient, six RPDs were positioned according to the dose distribution. VMAT SABR and IMRT/VMAT plans employed a 2%/2 mm gamma criterion, whereas IMRT/VMAT plans used a 3%/2 mm gamma criterion, a 10% threshold value, and a 90% passing rate tolerance. 3D gamma analysis was conducted using the 3D Slicer software.ResultsThe average gamma passing rates with 2%/2 mm and 3%/3 mm criteria for relative dose distribution were 91.6% ± 1.4% and 99.4% ± 0.7% for the 3D gamma analysis using the quasi‐3D dosimetry system, respectively, and 97.5% and 99.3% for 2D gamma analysis using MapCHECK2, respectively. The 3D gamma analysis for patient‐specific QA of 20 patients showed passing rates of over 90% with 2%/2 mm, 3%/2 mm, and 3%/3 mm criteria.ConclusionsThe quasi‐3D dosimetry system was evaluated by performing patient‐specific QAs with RPDs and quasi‐3D phantom. The gamma indices for all RPDs showed more than 90% for 2%/2 mm, 3%/2 mm, and 3%/3 mm criteria. We verified the feasibility of a quasi‐3D dosimetry system by performing the conventional patient‐specific QA with the quasi‐3D dosimeters.
Management of urinary incontinence after radical cystectomy and orthotopic neobladder: A scoping review of international practices
Authors: Miao ShuYing , He QingWei , Zhang YuanFeng , Wang LiJuan , Jin XiaoDong , Bao ChunXiang , Wang Wei 
Published: July 2023

AbstractObjectivesTo identify and describe international practice in incontinence management after radical cystectomy and orthotopic neobladder.Materials and MethodsA systematic scoping review following the methodology of the Joanne Briggs Institute was conducted in which the application searched 15 data sources to identify papers published in English, from 1979 to 2022.ResultsOf the 16 papers that met the eligibility criteria, articles in Eastern countries mainly focus on the effect of conservative treatment, while in Western countries, more attention is paid to the effect of surgical treatment. Clinical characteristics of patients included conservative treatment failure, duration of post‐operative intervention and unique differential treatment of male and female patients. Reported factors influencing the achievement of urinary incontinence (UI) include lack of evidence to guide management practice, limited value of conservative treatment, high risk of surgical treatment and uncertainty of efficacy; currently, early behavioural research and multimodal rehabilitation training have good results.ConclusionsUI in neobladder patients is a distressing condition that is difficult to treat and often requires high‐quality rehabilitation guidance and surgical intervention. Further research to address current knowledge gaps is important to inform practice.
Two‐sided Krylov enhanced proper orthogonal decomposition methods for partial differential equations with variable coefficients
Authors: Wang Li , Miao Zhen , Jiang Yao‐Lin 
Published: July 2023

AbstractIn this paper, new fast computing methods for partial differential equations with variable coefficients are studied and analyzed. They are two kinds of two‐sided Krylov enhanced proper orthogonal decomposition (KPOD) methods. First, the spatial discrete scheme of an advection‐diffusion equation is obtained by Galerkin approximation. Then, an algorithm based on a two‐sided KPOD approach involving the block Arnoldi and block Lanczos processes for the obtained time‐varying equations is put forward. Moreover, another type of two‐sided KPOD algorithm based on Laguerre orthogonal polynomials in frequency domain is provided. For the two kinds of two‐sided KPOD methods, we present a theoretical analysis for the moment matching of the discrete time‐invariant transfer function in time domain and give the error bound caused by the reduced‐order projection between the Galerkin finite element solution and the approximate solution of the two‐sided KPOD method. Finally, the feasibility of four two‐sided KPOD algorithms is verified by several numerical results with different inputs and setting parameters.
Attack‐defense differential game to strength allocation strategies generation
Authors: Li Lingwei , Xiao Bing , Su Shihong , Zhang Haichao , Wu Xiwei , Guo Yiming 
Published: July 2023

AbstractThis paper addresses a difficult problem of strength allocation strategies generation with various adversaries and complex factors. Firstly, to investigate the strength allocation strategies generation problem, an attack‐defense differential game problem is formulated based on an improved Lanchester equation. Secondly, a numerical method, multi‐intervals simultaneous orthogonal collocation decomposition (MISOCD) method, is proposed to obtain the strength allocation strategies from the constructed model. Compared with the analytical method, MISOCD does not need to derive the necessary conditions. Thirdly, this study designs an approximated solution generation strategy based on adaptive learning pigeon‐inspired optimization algorithm to pregenerate the approximated strength allocation strategies in order to solve the initial value sensitivity problem. The approximated strategies are then used as the initial value guess of MISOCD method to generate optimal strength allocation strategies. Finally, two attack‐defense numerical simulations verify the effectiveness of strength allocation strategies generated by the proposed approach. Our proposed results provide a theoretical guide for both making attack‐defense strength allocation strategies and assessing confrontation actions.
Factors leading to supranormal cardiac index in pediatric pulmonary hypertension patients treated with parenteral prostanoid therapy
Authors: Miles Kimberley G. , Critser Paul J. , Evers Patrick D. , Cash Michelle , Magness Melissa , Geers Elizabeth , O'Neil Meredith , Gao Zhiqian , Ollberding Nicholas J. , Hirsch Russel 
Published: July 2023

AbstractParenteral prostanoid therapy (PPT) can result in supranormal cardiac index (SCI; >4 L/min/m2) in pediatric pulmonary hypertension (PPH) patients. We evaluated the incidence, hemodynamic factors, and outcomes associated with SCI in PPH. This retrospective cohort study included 22 PPH patients on PPT from 2005 to 2020. Hemodynamic profiles were compared between the baseline and 3–6 month follow‐up catheterization in the SCI and non‐SCI cohorts. Cox regression analysis examined time to composite adverse outcome (CAO; Potts shunt, lung transplant, or death) controlling for initial disease severity. SCI developed in 17 (77%) patients, of whom 11 (65%) developed SCI within 6 months. The SCI cohort was characterized by significant augmentation of cardiac index (CI) and stroke volume (SV) as well as reductions in systemic vascular resistance (SVR) and pulmonary vascular resistance (PVR). Conversely, the non‐SCI cohort had unchanged SV despite a modest rise in CI as well as persistent vasoconstriction. After median follow‐up of 4.3 years (range 0.2–13 years), non‐SCI patients were at significantly increased risk for the CAO (5/5: three deaths, two Potts shunts) compared with SCI patients (5/17: two deaths, three lung transplants; adjusted hazard ratio 14.0 [95% confidence interval: 2.1–91.3], p < 0.001). A majority of PPH patients developed SCI within 6–12 months of starting PPT and demonstrated lower risk of adverse outcomes compared with non‐SCI patients. These data suggest that change in SVR and SV after 3–6 months of PPT may be early markers of therapeutic response and prognosis.
Recent Advances and Perspectives on the Promising High‐Voltage Cathode Material of Na3(VO)2(PO4)2F
Authors: Yin Ya‐Meng , Pei Cunyuan , Xia Wei , Luo Xiaojun , Li Dong‐Sheng 
Published: July 2023

AbstractNa3(VO)2(PO4)2F (NVOPF) has emerged as one of the most promising cathode materials for sodium‐ion batteries (SIBs) attributed to its high specific capacity (130 mAh g−1), high operation voltage (>3.9 V vs Na+/Na), and excellent structural stability (<2% volume change). However, the comparatively low intrinsic electronic conductivity (≈10−7 S cm−1) of NVOPF leads to unsatisfactory electrochemical performance, especially at high rates, limiting its practical applications. To improve the conductivity and enhance Na storage performance, many efforts have been devoted to designing NVOPF, including morphology optimization, hybridization with conductive materials, metal‐ion doping, Na‐site regulation, and F/O ratio adjustment. These attempts have shown some encouraging achievements and shed light on the practical application of NVOPF cathodes. This work aims to provide a general introduction, synthetic methods, and rational design of NVOPF to give a deeper understanding of the recent progress. Additionally, the unique microstructure of NVOPF and its relationship with Na storage properties are also described in detail. The current status, as well as the advances and limitations of such SIB cathode material, are reported. Finally, future perspectives and guidance for advancing high‐performance NVOPF cathodes toward practical applications are presented.
Shear design and life cycle assessment of novel limestone calcined clay cement reinforced concrete beams
Authors: Huang Zhenyu , Deng Weixiong , Zhao Xiaolong , Zhou Yingwu , Xing Feng , Hou Pengkun , Chen Cheng 
Published: July 2023

AbstractTo reduce the impact on global warming, many countries and regions are advocating the use of low‐carbon and green supplementary cementitious materials (SCMs) to improve the cement industry. This study investigates the shear behavior of reinforced concrete (RC) beams made with a novel green concrete, limestone, calcined clay, and cement clinker (LC3). Full‐scale shear tests were conducted on RC and LC3‐RC beams to evaluate their fundamental behavior for structural applications. The shear resistance of LC3 concrete beams was evaluated using Chinese, American, and Eurocode codes, while carbon emission and environmental impact were analyzed by life cycle assessment (LCA). Results showed that LC3‐RC and RC beams exhibited similar shear behavior in terms of crack initiation, propagation, and development. The increase in concrete strength improved the stiffness of LC3‐RC specimens, while RC specimens remained unchanged. The ductility of RC specimens was inversely proportional to concrete strength, while LC3‐RC beams exhibited optimal ductility. The increase in stirrup ratio significantly improved the shear resistance of both LC3‐RC and RC beams. With increased shear‐span ratio, the failure mode of LC3 specimens improved, changing from diagonal‐compression to shear compression or diagonal tension failure. The shear resistance of both LC3‐RC and RC beams was underestimated by GB 50010‐2010, ACI 318‐19, and Eurocode 2. LC3 concrete significantly reduced energy consumption and carbon emissions and achieved favorable environmental benefits in terms of GWP, PMFP, POFP, TAP, and TETP. Increasing usage of limestone in LC3 may further decrease environmental potential without sacrificing mechanical properties. The findings of this study contribute to the development of sustainable and environmentally friendly structures in engineering.
Corporate governance transparency: Do firm‐level ethics policies and country‐level investor protections substitute or complement?
Authors: Weber Thomas , Moghaddam Kaveh , Lewellyn Krista B. , Maleki Amirhossein 
Published: July 2023

AbstractThis study empirically investigates the direct and interactive effects of firm‐level ethics policies and country‐level investor protection on firm corporate governance transparency. Using data on 9298 firms collected from the Bloomberg Terminal, we find that there is a positive relationship between country‐level investor protection and firm corporate governance transparency. The results also support the argument that firms with existing ethics policies exhibit greater corporate governance transparency. We also find that in countries with weaker investor protection, the impact of firm‐level ethics policies on corporate governance transparency is stronger. This study advances our understanding of the corporate governance transparency determinants, and the empirical evidence supports the notion that firm‐level factors such as ethics policies may compensate for the lack of formal national investor protection regulations.
Innocent heroes or self‐absorbed alarmists? A thematic review of the variety and effects of storylines about young people in climate change discourses
Authors: Jones Charlotte A. , Davison Aidan , Lucas Chloe 
Published: July 2023

AbstractDiscourses about young people are interacting with climate change discourses in ways that often marginalize the young in social responses to climate change. The resulting stories about young people in a changing climate build upon long‐standing representations of youthhood in late modern societies as a liminal, ill‐defined state between childhood and adulthood. The social and behavioral sciences have both helped produce these stories and critically examined their origins, characteristics, and effects. This article offers a novel critical review of ideas about young people in climate change research across a wide variety of disciplines and fields, including geography, psychology, sociology, education, political studies, health studies, media studies, legal studies, and youth studies. We employ Hajer's account of discursive storylines to identify seven ways in which young people are storied in climate discourses. While distinct, stories of young people as innocent, vulnerable, heroic, alarmist, inheriting, apathetic or narcissistic overlap, and interact. This variety of storylines reflects the mutable category of young people and the deliberate ambiguity with which it is often deployed. We use this typology in three ways to advance the interests of young people in climate change discourses. First, we show how these discourses are indebted to while also changing understandings of young people in late modern societies. Second, we consider the potential impacts of these stories on young lives and on responses to climate change. Third, we identify prospects for new stories to emerge as young voices become increasingly important in urgent social discussions of climate change.This article is categorized under:
Perceptions, Behavior, and Communication of Climate Change > Communication
Perceptions, Behavior, and Communication of Climate Change > Perceptions of Climate Change
Spin supplementary condition in quantum field theory: covariant SSC and physical state projection
Authors: Kim Jung-Wook , Steinhoff Jan 
Published: July 2023

Abstract
The spin supplementary conditions are constraints on spin degrees of freedom in classical relativity which restricts physical degrees of freedom to rotations. It is argued that the equivalent constraints in quantum field theory are the projection conditions on polarisation tensors, which remove timelike/longitudinal polarisations from the physical spectrum. The claim is supported by three examples of massive spinning particles coupled to electromagnetism: Dirac and Proca fields in quantum field theory, and 𝒩 = 1 worldline QFT for classical worldline theory. This suggests a resolution to the apparent discrepancy between effective field theory description of massive higher-spin fields [1, 2] and post-Newtonian effective field theory of spinning classical particles [3], where the former admits more unfixed parameters compared to the latter; the additional parameters are fixed by projection conditions and therefore are not tunable parameters.
The emerging roles of long noncoding RNAs in lymphatic vascular development and disease
Authors: Ivanov Konstantin I. , Samuilova Olga V. , Zamyatnin Andrey A. 
Published: July 2023

AbstractRecent advances in RNA sequencing technologies helped uncover what was once uncharted territory in the human genome—the complex and versatile world of long noncoding RNAs (lncRNAs). Previously thought of as merely transcriptional “noise”, lncRNAs have now emerged as essential regulators of gene expression networks controlling development, homeostasis and disease progression. The regulatory functions of lncRNAs are broad and diverse, and the underlying molecular mechanisms are highly variable, acting at the transcriptional, post-transcriptional, translational, and post-translational levels. In recent years, evidence has accumulated to support the important role of lncRNAs in the development and functioning of the lymphatic vasculature and associated pathological processes such as tumor-induced lymphangiogenesis and cancer metastasis. In this review, we summarize the current knowledge on the role of lncRNAs in regulating the key genes and pathways involved in lymphatic vascular development and disease. Furthermore, we discuss the potential of lncRNAs as novel therapeutic targets and outline possible strategies for the development of lncRNA-based therapeutics to treat diseases of the lymphatic system.