bluuebunny/crossref_metadata_2025_split huggingface dataset:
PEMBERDAYAAN MASYARAKAT TERDAMPAK COVID 19 MELALUI USAHA BUDIDAYA LELE PADA LAHAN PERKEBUNAN DI DESA GALUNGAN, BULELENG
Authors: Pebriani D.A.A. , Negara I.K.W. , Wijayanti N.P.P. , Suryaningtyas E.W. , Pratiwi M.A. 
Published: July 2023

Adanya COVID-19 telah menimbulkan dampak yang sangat besar terhadap kondisi perekonomian di seluruh dunia, salah satu bidang usaha yang sangat besar terkena dampak pandemi ini adalah bidang usaha kegiatan pariwisata. Masyarakat di Provinsi Bali hingga saat ini sangat mengandalkan usaha pada bidang pariwisata yang secara langsung mengalami dampak yang sangat luar biasa terjadi goncangan ekonomi, sehingga kondisi tersebut mengkibatkan beberapa masyarakat yang menggantungkan hidup dari pariwiasata memilih untuk kembali ke desa asal akibat di PHK atau kerugian akibat usaha yang tidak menguntungkan. Kabupaten Buleleng memiliki luas daerah 1.365,88 km² atau 24,25% dari Luas Pulau Bali, sehingga memiliki wilayah daratan dan perairan terluas di Provinsi Bali. Banyak kegiatan yang dapat dijadikan sebagai sumber mata pencaharian di masa pandemi ini, salah satunya kegiatan budidaya ikan. Budidaya ikan lele menjadi salah satu pilihan kegiatan di tengah masa pandemi ini karena praktis dan menghasilkan. Praktis karena mudah diaplikasikan bahkan dapat menggunakan lahan perkebunan sebagai lokasi budidaya dan menghasilkan karena hasil panennya selain dapat dikonsumsi bagi pelaku budidaya juga dapat dijual yang tentunya memberikan nilai ekonomi. Tujuan dari kegiatan pengabdian ini adalah untuk memberikan solusi permasalahan peluang ekonomi kepada masyarakat yang terdampak COVID-19 dan pemanfaatan lahan perkebunan untuk budidaya lele dengan aplikasi kolam terpal bulat, sehingga tidak mengganggu komoditas utama dari lahan perkebunan tersebut. Kolam terpal merupakan salah satu solusi untuk pengembangan budidaya lele pada lahan perkebunan agar lahan tersebut selain mendapatkan produksi dari komoditas utamanya juga mendapatkan hasil tambahan dari produksi lele. Kegiatan pengabdian berlangsung pada tanggal 21 Agustus 2021 di Desa Galungan dengan melibatkan masyarakat mulai dari tahap persiapan, pelaksanaan, dan evaluasi. Masyarakat sangat antusias mengikuti pemaparan dari Bapak Dr. Pande Gde Sasmita Julyantoro, S.Si.,M.Si dan Bapak Nyoman Agus Sudarta, S.Pi dilihat dari feedback yang diberikan masyarakat berupa pertanyaan terkait dengan budidaya ikan lele dengan menggunakan kolam terpal.

Kata kunci : metode Budidaya, lele (Clarias sp.), pemberdayaan masyarakat, Desa Galungan
Tilt Angle of Solar Panels for Best Winter, Summer and Year-Round Performances for Different Regions of the World
Authors: Salih Aqeel R. 
Published: July 2023

Background:
In recent years, solar energy has gained increased attention. The energy from the sun is unlimited and environment friendly. It is useful in decreasing the carbon dioxide emission that comes from the burning of fossil fuels and leads to global warming.
Materials and Methods:
The tilt angle of a solar panel is an important parameter that affects its performance. This paper provides the tilt angle of solar panels for 90 capital cities in 90 countries in the northern and southern hemispheres. Solar Irradiance Calculator is used to calculate the tilt angles from vertical.
Results:
The tilt angle for the studied capital cities ranges from 11° to 90° in winter, 41° to 105° in summer and 26° to 90° for year-round. The output results obtained from the calculator are very close to those calculated from equations and agree with previous studies.
Conclusions:
According to the results of the current work, only the latitude is required to calculate the tilt angle at any location worldwide. These results can be generalized to any location on the earth. The results of this work are expected to give valuable information to the users of solar panels.
Effect of viral eradication with direct-acting antiviral agents on iron parameters in patients with chronic hepatitis c and hyperferritinemia
Authors: Castiella Agustin , José Sánchez-Iturri María , Urreta Iratxe , Torrente Silvia , Alcorta Ana , Zapata Eva 
Published: July 2023

Background: Patients with chronic hepatitis C are at increased risk for hyperferritinemia (HF). Abnormalities of serum iron parameters are frequently observed in patients with chronic hepatitis C (CHC). About a third of patients have increased iron parameters. Recently, studies on the effect of direct-acting antiviral agents (DAAs) in HCV eradication in patients with increased serum iron has been published, demonstrating the restoration of normal iron status. The aim of this study was to evaluate the effect of viral eradication with DDAs in patients with CHC and HF. Methods: Retrospective study conducted from January 2018 to December 2020 including patients treated with DAAs for HCV. Pre-treatment (PreT) and post-treatment (PostT) serum ferritin values were evaluated in all patients. Inclusion criteria: Pret HF (>400 μg/L); CHC patients treated with DAA achieving sustained viral response (SVR). Exclusion criteria: No PreT or PostT HF available; no SVR; lost patients. Results: From 621 patients treated with DAAs for CHC, 77 presented HF (12.40%), and 74 were included in the study. Fifty nine were men (79.73%) with a mean age 58.33, SD 8.68; PreT mean ferritin: 893.20 (SD 1037.09); PostT: 264.17 (SD 161.33); PreT mean transferrin saturation: 40.96 (SD 15.71); PostT: 29.82 (SD 11.17); PreT mean serum iron 152.32 (SD 62.07), PostT: 109.32 (SD 39.49). When we compared PreT and PostT iron parameters, significant statistical differences were present considering ferritin ( p = 0.0000), transferrin saturation ( p = 0.0000), and iron ( p = 0.0002) determinations. Conclusions: SVR after DAAs for CHC induces a statistically significant reduction on iron parameters.
PENGARUH WHISTLEBLOWING, KOMPETENSI SUMBER DAYA MANUSIA DAN INTERNAL CONTROL SYSTEM TERHADAP PENCEGAHAN FRAUD DANA PSR
Authors: Andini  
Published: July 2023

Peremajaan Sawit Rakyat (PSR) is a program to help smallholders renew their oil palm plantations with more sustainable, quality palm oil, reducing the risk of illegal land clearing. In an effort to prevent fraud / fraud of PSR funds, BPDKS distributes funds through escrow accounts of plantation institutions. This is for transaction security. Furthermore, in the implementation of PSR, an audit was carried out by BPK and Sucofindo as institutions appointed by BPDPKS. Fraud prevention can be influenced by several factors such as whistleblowing, human resource competence and internal control system. Whistleblowing as disclosure of unlawful acts, unethical and immoral acts or other acts that can cause losses to the organization and stakeholders. The purpose of this study is: To determine the effect of whistleblowing on Fraud Prevention, HR Competence and Internal Control System affect Fraud Prevention. Research variables (whistleblowing, human resource competence and internal control system) with a total of 52 samples. Descriptive statistical analysis is used to determine the tendency of each research variable. The average whistleblowing score, human resource competence and internal control system were 32.46, 26.96 and 63.77. The average fraud prevention score was 41.25. Based on the results of the study, it can be concluded Whistleblowing, Human resource competence and 3. Internal control system affects the prevention of fraud of PSR funds.
Inklusi Teologi : Antara Agama dan Teknologi dalam Perspektif Naquib Al-Attas
Authors: Septy Oktavia  , Diva Try Syafrielia  , Khoirun Nisa Alhabibah  , Lisa Qotrun Nandini  
Published: July 2023

The relationship between religion and technology is an important topic in the study of religion and technological development. Nauqib, a muslim scientist, provides a unique perspective on this matter. Nauqib realizes thet technology can make it easier to worship and spread religious messages, but he also realize that technology can have a negative impact on moral and spiritual values. Nauqib emphasizes the importance of education and awareness of technological ethics for muslim, so that they can utilize technology for good and not become slaves to technology. Nauqib also highlights the importance of the involvement of religious scholars and leaders in technology development. Nauqib’s perspective underscores the importance of harmony between religion and technology. Technology can be useful tool for muslims in strengthening religious practice and improving quality of life, provided it is used wisely and does not violte religious principles.
Teknik Coaching Untuk Memahami Karakteristik Siswa Dalam Kurikulum Merdeka Belajar
Authors: Kusumardi Adi 
Published: July 2023

Penulisan artike lini bertujuan untuk memberi pengetahuan kepada para pembaca bagaimana penerapan teknik coaching dalam Pendidikan untuk memahami karakteristik siswa agar dapat memaksimalkan pembelajaran. Metode penelitian yang digunakan adalah metode kualitatif (studi litelatur ) data diperoleh dari berbagai referensi baik buku, jurnal yang relevan dan fenomenologi. Hasil penelitian menggambarkan bahwa, penerapan teknik coaching yang efektif diterapkan adalah: (1) Coaching presence; (2) Active listening; (3) Powerful questioning. Penerapan kompetensi teknik coaching yang benar dapat memahami karakteristik gaya belajar siswa, seperti; gaya belajar visual (belajar dengan cara melihat), gaya belajar auditori ( gaya belajar dengan kemampuan mendengarkan) dan gaya belajar kinestetik (gaya belajar dengan praktik). Guru dapat membuat media pembelajaran yang lebih bervariasi dan mengembangkan metode serta strategi pembelajaran yang lebih efektif. Dari hasil penelitian dapat disimpulkan, bahwa pemahaman terhadap karakteristik siswa baik dari kecerdasan maupun gaya belajar yang beragam dapat menumbuhkan perasaan nyaman untuk belajar di sekolah. Pembelajaran tidak dapat berjalan dengan baik bila menggunakan teknik atau konsep samarata, karena siswa memiliki karakteristik yang beragam. Penerapan teknik coaching akan meningkatkan keberhasilan ketercapaian tujuan pembelajaran tanpa harus memberikan tekanan kepada siswa. Pada kondisi ini, pembelajaran akan berjalan secara alami kodratnya para siswa sehingga tujuan dari pembelajaran akan mudah tercapai dan menguntungkan guru serta siswa.
STABILITY ANALYSIS OF A SHIGELLA INFECTION EPIDEMIC MODEL AT ENDEMIC EQUILIBRIUM
Authors: Ochi Philip O. , Agada A. A. , Timothy Jeremiah , Urum T. G. , Ochi H. T. , Nworah Damascus Arinze 
Published: July 2023

In this study, we modified continuous mathematical model for the dynamics of shigella outbreak at constant recruitment rate formulated by (Ojaswita et al., 2014). In their model, they partitioned the population into Susceptible (S), Infected (I) and recovered (R) individuals. We incorporated a vaccinated class (V), educated class (G), exposed class (E), asymptomatic (A) hospitalized class (H) and Bacteria class (B) with their corresponding parameters. We analyzed a SVGEAIHRB compartmental nonlinear deterministic mathematical model of shigella epidemic in a community with constant population. Analytical studies were carried out on the model using the method of linearized stability. The basic reproductive number that governs the disease transmission is obtained from the largest eigenvalue of the next-generation matrix. The endemic equilibrium is computed and proved to be locally and globally asymptotically stable if and unstable if . Finally, we simulate the model system in MATLAB and obtained the graphical behavior of the infected compartments. From the simulation, we observed that the shigella infection was eradicated when while it persist in the environment when .
STUDIES ON PREVALENCE OF TRYPANOSOME INFECTION IN ABATTOIRS IN ASABA, DELTA STATE, NIGERIA
Authors: Chibuogwu Francisca U. , Ajunwa Linda O. , Oyo A. Ekpo , Preye Tarela M. , Ebulue Rose O. , Achagwa S. Musa , Onyeagu Chika L. , Enoh Emmanuel , Ofikwu Paula O. , Jonah Alice O. 
Published: July 2023

This study investigated the prevalence of trypanosome infection in cattle and Red Sokoto (R.S) goats slaughtered at abattoirs in Asaba, Delta State. 304 animals comprising 265 cattle, 39 R.S goats were examined. Blood was collected from the jugular vein of each animal into EDTA containers, placed in cold boxes and transported to the Nigerian Institute for Trypanosomiasis Research (NITR) laboratory in Asaba where standard trypanosome detection methods (STDM), Haematocrit centrifugation technique (HCT) and Buffy coat methods were used to detect trypanosomes and determine Packed Cell Volume (PCV). The result of the investigation showed that seventeen (17) animals were infected giving an overall prevalence of 5.59%. Fifteen (5.66%) of the cattle and two (5.13%) of the R.S goats were infected. Female cattle had higher prevalence of trypanosomiasis (6.78%) than the male cattle (4.76%). Difference in prevalence in female and male cattle was statistically significant (p<0.05). In R.S goats, 6.45% prevalence was observed in the males while no infection was found in the females. Three species of Trypanosoma namely, Trypansoma vivax, T. congolense and T. brucei brucei were recorded in infected animals. T. vivax, T. congolense and T. brucei brucei were found in the cattle while only T. congolense was found in R.S goats. There was a significant difference between the mean PCV value of infected animals and the non-infected animals (p < 0.05). The result of this study clearly indicates the presence of trypanosome species in the abattoir animals.
Protocol of a feasibility randomised controlled trial of Empowered Conversations: training family carers to enhance their relationships and communication with people living with dementia.
Authors: Eastham Cassie , Mansell Warren , Sutton Chris , Prior Yeliz , Keady John , Shields Gemma , Riley Cathy , Bowker Gail , Sylvestre Yvonne , Morris Lydia 
Published: July 2023

Background: Communication difficulties can cause frustration, low mood, and stress for people living with dementia and their carer. Carers should be offered training on adapting their communication skills. However, it is not common for skills-based education to examine emotional aspects of care and the effect of dementia on relationships. The Empowered Conversations (EC) training course was developed in response to a gap in service provision and has been adapted to a virtual format (Zoom). It addresses the specific psychological, relationship, and communication needs of informal and family dementia carers. The primary aim of the study is to investigate the feasibility of conducting a multi-centre randomised controlled evaluation trial of EC. Secondary aims include exploring the acceptability of delivering the intervention online and examining the optimum way of establishing cost-effectiveness. Methods: The feasibility trial uses a pragmatic data-collector blind parallel two-group RCT design with two arms (EC intervention plus treatment as usual, and treatment as usual waitlist control). There will be a 2:1 allocation in favour of the EC-training intervention arm. 75 participants will complete baseline outcome measures exploring their role as a carer, including their physical and mental health, attitudes to caring, quality of life, and use of health and social care services. These will be repeated after six-months. Participants allocated to the treatment group who complete the course will be invited to participate in a qualitative interview discussing their experience of EC. Discussion: The study will investigate recruitment pathways (including facilitators and barriers to recruitment), estimate retention levels and response rates to questionnaires, obtain additional evidence regarding proof of concept, and consider the most appropriate primary outcome measures and methods for evaluating cost-effectiveness. The results of the feasibility study will be used to inform the development of a multicentre randomised controlled trial in the United Kingdom. Registration: ISRCTN15261686 (02/03/2022)
Sox, Fox, and Lmx1b binding sites differentially regulate a Gdf5-Associated regulatory region during elbow development
Authors: Yeboah Ruth-Love , Pira Charmaine U. , Shankel Matthew , Cooper Allen M. , Haro Endika , Ly Van-Dai , Wysong Kenrick , Zhang Michael , Sandoval Nicole , Oberg Kerby C. 
Published: July 2023

Introduction: The articulating ends of limb bones have precise morphology and asymmetry that ensures proper joint function. Growth differentiation factor 5 (Gdf5) is a secreted morphogen involved in cartilage and bone development that contributes to the architecture of developing joints. Dysregulation of Gdf5 results in joint dysmorphogenesis often leading to progressive joint degeneration or osteoarthritis (OA). The transcription factors and cis-regulatory modules (CRMs) that regulate Gdf5 expression are not well characterized. We previously identified a Gdf5-associated regulatory region (GARR) that contains predicted binding sites for Lmx1b, Osr2, Fox, and the Sox transcription factors. These transcription factors are recognized factors involved in joint morphogenesis and skeletal development.Methods: We used in situ hybridization to Gdf5, Col2A1, and the transcription factors of interest in developing chicken limbs to determine potential overlap in expression. We further analyzed scRNA-seq data derived from limbs and knees in published mouse and chicken datasets, identifying cells with coexpression of Gdf5 and the transcription factors of interest. We also performed site-directed mutatgenesis of the predicted transcription factor binding sites in a GARR-reporter construct and determined any change in activity using targeted regional electroporation (TREP) in micromass and embryonic chicken wing bioassays.Results:Gdf5 expression overlapped the expression of these transcription factors during joint development both by in situ hybridization (ISH) and scRNA-seq analyses. Within the GARR CRM, mutation of two binding sites common to Fox and Sox transcripstion factors reduced enhancer activity to background levels in micromass cultures and in ovo embryonic chicken wing bioassays, whereas mutation of two Sox-only binding sites caused a significant increase in activity. These results indicate that the Fox/Sox binding sites are required for activity, while the Sox-only sites are involved in repression of activity. Mutation of Lmx1b binding sites in GARR caused an overall reduction in enhancer activity in vitro and a dorsal reduction in ovo. Despite a recognized role for Osr2 in joint development, disruption of the predicted Osr2 site did not alter GARR activity.Conclusion: Taken together, our data indicates that GARR integrates positive, repressive, and asymmetrical inputs to fine-tune the expression of Gdf5 during elbow joint development.
Single-cell transcriptomic landscape of immunometabolism reveals intervention candidates of ascorbate and aldarate metabolism, fatty-acid degradation and PUFA metabolism of T-cell subsets in healthy controls, psoriasis and psoriatic arthritis
Authors: Peng Lu , Chen Ling , Wan Jianji , Liu Wenqi , Lou Shuang , Shen Zhu 
Published: July 2023

IntroductionThe modulation of immunometabolic pathways is emerging as a promising therapeutic target for immune-mediated diseases. However, the immunometabolic features of psoriatic disease and the potential targets for immunometabolic intervention in the different T-cell subsets involved in its pathogenesis remain unclear.MethodsIn this study, we analyzed circulating blood single-cell data from healthy controls (HC), psoriasis (PSO), and psoriatic arthritis (PSA) patients, and revealed their metabolic features of T-cell subsets: CD4+ central memory T cells (TCMs), CD8+ effective memory T cells (TEMs), regulatory T cells (Tregs), mucosal-associated invariant T cells (MAITs ), and γδ T cells. Pearson test was performed to determine the linkages between differential metabolic and inflammatory pathways. Based on these results, we also analyzed the potential impacts of biological antibodies on differential metabolic pathways by comparing the immunometabolism differences between PSA patients without and with biological treatment.ResultsOur results suggest that upregulation of ascorbate and aldarate metabolism, as well as fatty acid degradation, may enhance the immune suppression of Tregs. Enhanced metabolism of alpha-linolenic acid, linoleic acid, and arachidonic acid may inhibit the pro-inflammatory functions of CD4+ TCMs and CD8+ TEMs in PSO and PSA, and protect the immune suppression of Tregs in PSA. We propose that supporting ascorbic acid and fatty acid metabolic pathways may be an adjunctive reprogramming strategy with adalimumab and etanercept therapy.DiscussionThese findings not only provide insights into immunometabolism characteristics of psoriatic disease, but also offer preliminary options for the auxiliary treatment of psoriasis.
Interspecies and spatial differences in the shell microbiome of Atlantic rock crab Cancer irrotatus and European green crab Carcinus maenas from Atlantic Canada
Authors: Koepper Svenja , Kelley Shannon , Thakur Krishna Kumar , Clark K. Fraser 
Published: July 2023

IntroductionThe native Atlantic rock crab (Cancer irrotatus) and the invasive European green crab (Carcinus maenas) are commercially and ecologically important crustacean species in Atlantic Canada. The importance of microbiomes for host health and ecology has been recognized in many species, although very few studies have focused on crustaceans or their external shell microbiome. This is the first-ever study to characterize and analyze the microbial communities associated with the external carapace of C. irrotatus and C. maenas.MethodsMicrobiome samples were collected from three locations in Atlantic Canada, processed using standard 16S Illumina MiSeq PE250 sequencing and analyzed with the open-access QIIME2 software.ResultsTaxonomic classification of the microbial compositions, as well as alpha- and beta diversities, reveal that the shell microbiome differs by host species between C. irrotatus and C. maenas sampled from the same location and between C. irrotatus sampled from different locations. Interestingly, the differences are greater between species at the same location than between locations for the same species.DiscussionThese are the first-ever results showing that the crustacean shell microbiome not only depends on geographical factors but also on intrinsic factors specific to the host species. This implies that crustaceans exert some impact on their shell microbiome, potentially selecting beneficial taxa. These are important findings that could elucidate contributing factors of crustacean shell diseases that are still poorly understood.