bluuebunny/crossref_metadata_2025_split huggingface dataset:
“Eye health, just ... part of helping a child to thrive”: Global and national influences on integrating eye health into a child health policy in Tanzania
Authors: Malik Aeesha Nusrat Jehan NJ , Spicer Neil , Mafwiri Milka , Gilbert Clare , Schellenberg Joanna 
Published: March 2023

Abstract
Background
Blindness and visual loss in early childhood can affect psychomotor, cognitive and social development leading to life-long consequences on educational attainment, employment, economic and social status, and wellbeing. Despite this, eye health for children under the age of five has been neglected, with little political priority as a child health issue. In Tanzania, policy makers decided in 2019 to include eye conditions in the national Integrated Management of Newborn and Childhood Illness (IMNCI) strategy, despite eye health not being in the global WHO/UNICEF strategy for IMNCI.
Results
We conducted a qualitative policy analysis to explore enabling factors and barriers to this policy change, using semi-structured interviews with key actors involved in child and eye health at national level and also explored if there were global level influencing factors. We found that the key determinants were the leveraging of existing policy communities and networks; clear consensus on framing of ideas within the policy and advocacy community and to policy makers; generating local evidence with policy communities; and a critical IMNCI policy window in Tanzania, together with the expansion of global child health policy which now includes early childhood development. Global governance structures, guiding institutions, and major funding or civil societies did not influence the policy change in Tanzania.
Conclusions
This study shows how child eye health advocates and funders can influence integration of eye health into the IMNCI strategy in one country. A global policy shift in child health to enable young children to ‘thrive’ as well as ‘survive’ provides a major window of opportunity in over 100 countries for eye health to be integrated into IMNCI and other national and global child health policies. Generating local evidence in collaboration with policy makers and child health policy communities, and a clear framing of the problems and their solutions will be critical factors in enabling the inclusion of eye health into child health policies.
Vacancy-mediated anomalous phononic and electronic transport in defective half-Heusler ZrNiBi
Authors: Ren Wuyang , Xue Wenhua , Guo Shuping , He Ran , Deng Liangzi , Song Shaowei , Sotnikov Andrei , Nielsch Kornelius , Brink Jeroen van den , Gao Guanhui , Chen Shuo , Han Yimo , Wu Jiang , Chu Ching-Wu , Wang Zhiming , Wang Yumei , Ren Zhifeng 
Published: March 2023

Abstract
Studies of vacancy-mediated anomalous transport properties have flourished in diverse fields since they endow solid materials with fascinating photoelectric, ferroelectric, and spin-electric behaviors. Although phononic and electronic transport underpin the physical origin of thermoelectrics, vacancy has only played a stereotyped role as a scattering center. Here we reveal the multifunctionality of vacancy in tailoring the transport properties of an emerging thermoelectric material, defective n-type ZrNiBi. The phonon kinetic process is mediated in both propagating velocity and relaxation time: vacancy-induced local soft bonds lower the phonon velocity while acoustic-optical phonon coupling, anisotropic vibrations, and point-defect scattering induced by vacancy shorten the relaxation time. Consequently, defective ZrNiBi exhibits the lowest lattice thermal conductivity among the half-Heusler family. In addition, a vacancy-induced flat band features prominently in its electronic band structure, which is not only desirable for electron-sufficient thermoelectric materials but also interesting to drive other novel physical phenomena. Finally, better thermoelectric performance is established in a ZrNiBi-based compound. Our findings not only demonstrate a promising thermoelectric material but also promote the fascinating vacancy-mediated anomalous transport properties for multidisciplinary explorations.
The Effect of Ten vs. Twenty Minutes of Mindfulness Meditation on State Mindfulness and Affect
Authors: Palmer Robert , Roos Corey , Vafaie Nilofar , Kober Hedy 
Published: March 2023

Abstract
We aimed to elucidate the effects of “dose” of a single-session of mindfulness meditation on state mindfulness and affect as well as moderators of effects. 372 adults recruited remotely via Amazon’s MTurk platform were randomly assigned to either a: 10-minute mindfulness meditation, 20-minute mindfulness meditation, 10-minute control, or 20-minute control. Control conditions were recordings of a National Geographic article. Primary outcomes were changes in state mindfulness, anxiety, and negative and positive affect. Moderator variables included neuroticism, trait mindfulness, and prior meditation experience. Collapsing across doses, participants in mindfulness conditions reported greater increases in state mindfulness than in control conditions. There was a greater increase in state mindfulness in the 10-minute mindfulness condition vs. 10-minute control condition. There were no differences between 10- and 20-minute mindfulness conditions. Moderation analyses indicated that meditation (10 or 20) vs. control (10 or 20) predicted increased state mindfulness among participants with lower trait mindfulness. Additionally, 20-minute vs. 10-minute meditation predicted greater decreases in state anxiety among individuals with high trait mindfulness. Dose-response relationships were minimal, suggesting that 10 and 20 minutes of meditation may improve state mindfulness comparably. Findings support the benefits of brief mindfulness meditation and suggest that trait mindfulness moderates certain outcomes.
Application of data mining in female sports behavior prediction based on FCM algorithm
Authors: Yuan Liyun , Cao Jiaxing 
Published: March 2023

Abstract
Data mining is the process of continuously optimizing the problem to the goal. It has to meet the needs of the user, which means it has to unearth content that is useful or interesting to the user. This paper analyzes the data mining of female sports behavior prediction based on FCM algorithm. We modified the standard speech frequencies of the data into high-level descriptions, used various data mining methods to determine speech rules, and obtained good experimental results. Data mining technology is used to mine valuable information and knowledge hidden in a large amount of test security data, and make the acquired expertise into understandable rules or patterns, and then use the rules or patterns that have been created to effectively detect Guidelines for any activity suspected of attacking network data. The simulation results show that the data mining system in this paper can effectively predict and analyze the data.The results show that there are many differences among working women in terms of average annual consumption of sports and leisure activities, participation and consumption of sports and leisure activities. In addition, based on the results of the study, we will take more effective and specific references and measures to expand the participation of professional women in sports and leisure activities.
Transparent Charge Transfer Complex with High Thermoelectric Performance
Authors: Li Xiao-Lei , Zhang Gao , Zhang Xin , Zou Weitian , Li Ge , Zhang Xuefei , Li Yi , Zhang Lizhai , Wang Minqiang , Chen Bo , Wu Haijun , Wan Chunlei , Yang Guan-Jun 
Published: March 2023

Abstract
Searching n-type high-performance organic thermoelectric material with good air-stability and high transparency remains a big challenge. Here, we report an all-transparent n-type charge transfer complex [ZnBr2(Br-C6H4-NH2)2] with an ultra-wide band gap of 4.25 eV (~ 163 kBT). This material exhibits an ultrahigh electrical conductivity of ~ 2,936 S cm− 1 and a high Seebeck coefficient of − 114 µV K‒1, leading to an extraordinarily high power factor of ~ 3,797 µW m‒1 K‒2 at room temperature, which is a record value for organic thermoelectric materials. Remarkably, figure-of-merit (ZT) values of 0.23 at 298 K and 0.45 at 473 K were achieved, respectively. The ZT values are not only the state-of-the-art performance for n-type organic thermoelectric materials, but also better than those of some typical inorganic thermoelectric materials at near room-temperature range. The extraordinarily high thermoelectric performance is attributed to the electron transfer induced n-type heavily doped characteristic, high valley band degeneracy and heavy effective mass. Owing to its exceptional thermoelectric performance and excellent air-stability, [ZnBr2(Br-C6H4-NH2)2] can be considered as a milestone in the development of organic thermoelectric materials.
Peptide derived from progranulin of the carcinogenic liver fluke, Opisthorchis viverrini stimulates cell hyperproliferation and proinflammatory cytokine production.
Authors: Hembasat Thanapat , Chaiyadet Sujittra , Ittiprasert Wannaporn , Smout Michael J , Young Neil D , Loukas Alex , Brindley Paul J , LAHA THEWARACH 
Published: March 2023

Abstract
Purpose

Progranulin (PGRN) is a secreted glycoprotein growth factor with roles in wound healing, inflammation, angiogenesis and malignancy. An orthologue of the gene encoding human PGRN was identified in the carcinogenic liver fluke Opisthorchis viverrini.

Methods

Sequence structure, general characteristics and possible function of O. viverrini PGRN was analyzed using bioinformatics. Expression profiles were investigated with quantitative RT-PCR, western blot and immunolocalization. A specific peptide of Ov-PGRN was used to investigate a role for this molecule in pathogenesis.

Results

The structure of the gene coding for O. viverrini PGRN was 36,463 bp in length, and comprised of 13 exons, 12 introns, and a promoter sequence. The Ov-pgrn mRNA is 2,768 bp in length and encodes an 846 amino acids with a predicted molecular mass of 91.61 kDa. Ov-PGRN exhibited one half and seven complete granulin domains. Phylogenetic analysis revealed that Ov-PGRN formed its closest relationship with PGRN of liver flukes in the Opisthorchiidae. Transcripts of Ov-pgrn were detected in several developmental stages, with highest expression in the metacercaria, indicating that Ov-PGRN may participate as a growth factor in the early development of O. viverrini. Western blot analysis revealed the presence of detected Ov-PGRN in both soluble somatic or excretory/secretory products, and immunolocalization indicated high levels of expression in the tegument and parenchyma of the adult fluke. Co-culture of a human cholangiocyte cell line and a peptide fragment of Ov-PGRN stimulated proliferation of cholangiocytes and upregulation of expression of the cytokines IL6 and IL8.

Conclusion

Ov-PGRN is expressed throughout the life cycle of liver fluke, and likely plays a key role in development and growth.
Abl depletion via autophagy mediates the beneficial effects of quercetin against Alzheimer pathology across species
Authors: Schiavi Alfonso , Cirotti Claudia , Gerber Lora-Sophie , Lauro Giulia Di , Petzsch Patrick , Köhrer Karl-Erich , Schins Roel , Wahle Tina , Barilà Daniela , Ventura Natascia 
Published: March 2023

Abstract
Alzheimer's disease is the most common age-associated neurodegenerative disorder and the most frequent form of dementia in our society. Aging is a complex biological process concurrently shaped by genetic, dietary and environmental factors and natural compounds are emerging for their beneficial effects against age-related disorders. Besides their antioxidant activity often described in simple model organisms, the molecular mechanisms underlying the beneficial effects of different dietary compounds remain however largely unknown. In the present study, we exploit the nematode Caenorhabditis elegans as a widely established model for aging studies, to test the effects of different natural compounds in vivo and focused on mechanistic aspects of one of them, quercetin, using complementary systems and assays. We show that quercetin has evolutionarily conserved beneficial effects against AD pathology: it prevents Aβ-induced detrimental effects in different C. elegans AD models and it reduces Aβ-secretion in mammalian cells. Mechanistically, we found that the beneficial effects of quercetin are mediated by autophagy-dependent reduced expression of Abl tyrosine kinase. In turn, autophagy is required upon Abl suppression to mediate quercetin’s protective effects against Aβ toxicity. Our data support the power of C. elegans as an in vivo model to investigate therapeutic options for Alzheimer disease.
Microglial Annexin A2 Deficiency Supresses Inflammatory Response to Alleviate Ischemia Reperfusion-Induced Cerebral Injury
Authors: Tian Xibin , Yang Wuyan , Jiang Wei , Zhang Zhen , LIU Junqiang , Tu Haijun 
Published: March 2023

Abstract
Cerebral stroke is one of the leading causes of mortality and disability worldwide. Cerebral ischemia followed by reperfusion (I/R) triggers inflammatory responses, apoptosis, neuronal damage, and even death, while the molecular and cellular mechanisms of neuronal injury caused by cerebral I/R are not fully understood. Here, we integrated proteome, phosphoproteome and transcriptome profile analyses in mouse hippocampiafter I/Rand revealed that the differentially expressed genes (DEGs) and proteins (DEPs) mainly fall into several immune response-related events. Among 11 common DEGs/DEPs, we identified Annexin A2 (Anxa2) was exclusively up-regulated and translocated to membrane in microglial cells in response to oxygen-glucose deprivation followed by reoxygenation (OGD/R). Microglial Anxa2 knockdown suppressed M1- and promoted M2-microglia polarization induced by OGD/R, facilitated nuclear translocation of NF-κB p65 subunit, activated NF-κB transcriptional activity in response to OGD/R, suppressed the expression of OGD/R-induced pro-inflammatory factors including TNF-a, IL-1β, and IL-6, and reduced cell apoptosis in microglial BV2 cells. The conditional medium derived from Anxa2 knockdown-BV2 cell cultures with OGD/R treatment alleviated OGD/R induced-neuronal death . Our findings revealed that microglia Anxa2 plays a critical role in ischemia cerebral injury through inflammatory responses in a cell non-autonomous manner, which might be a potential target for the neuroprotection against I/R cerebral injury.
Influence of Fire and Disturbance-Altered Hydrology on the Abundance of Phragmites australis
Authors: Link Nicholas T , McLaughlin Daniel L. , Bush Nathan , Wurster Fredric C 
Published: March 2023

AbstractHistorical land-use conversion and drainage may increase the risk of high intensity, soil-consuming fires in peatlands. Severe fires may degrade ecosystem resilience through changes in hydrology and by removing remnant seed and bud banks. Given this, peatlands are highly susceptible to species invasions from aggressive colonizing species post-disturbance. In this work we aimed to address the impacts of smoldering fires on the abundance of the noxiousPhragmites australisin a large fire scar at the Great Dismal Swamp National Wildlife Refuge (VA and NC, USA). Primarily, we wanted to observe the extent of the relationship between the altered hydrology of post-fire conditions andP. australisoccurrence. We did so by leveraging high resolution satellite imagery, random forest models, LiDAR data, and water table observations. Our results suggest thatP. australisis aided by a hydrologic regime generated, in part, from the combined effects of drainage and deep smoldering fires. Our findings emphasize the importance of hydrologic management post-disturbance for limitingP. australisinvasion. Further, we highlight the potential for feedbacks between deep peat consuming burns andP. australisinvasions and spread in degraded peatlands.
The Impact of Green Accounting on Environmental Performance: Mediating Effects of Energy Efficiency
Authors: Rahman Md. Mominur , Islam Mohammad Ekramol 
Published: March 2023

Abstract
This study aims to investigate the relationship between green accounting and energy efficiency and environmental performance in the context of Bangladeshi pharmaceutical and chemical companies. The study also explores the mediating role of energy efficiency in the relationship between green accounting and environmental performance. A total of 326 responses were collected using a simple random sampling technique from pharmaceutical and chemical companies in Bangladesh. The study employed Partial Least Squares Structural Equation Modeling (PLS-SEM) to analyze the data. The results indicate that green accounting has a significant positive impact on both energy efficiency and environmental performance. Moreover, energy efficiency partially mediates the relationship between green accounting and environmental performance. The study also found that economic, environmental, and social practices of green accounting have a positive impact on both energy efficiency and environmental performance, with environmental practices having the highest impact. The findings of this study provide important insights for managers and policymakers of pharmaceutical and chemical companies in Bangladesh, highlighting the need for green accounting practices that promote environmental sustainability. The study suggests that the integration of green accounting practices can lead to better energy efficiency and environmental performance, which can enhance the reputation and competitive advantage of these companies. This study identifies the mediating role of energy efficiency in the relationship between green accounting and environmental performance, providing a unique perspective on the mechanism behind the relationship.
G/β-TCP composite scaffold facilitates the repairment of cartilage defect in rabbit knee joint
Authors: Su Hairong , Liao Yong , Yuan Xiaolu , Huang Jianhui , Chen Ya , Zhao Binxiu 
Published: March 2023

Abstract
Purpose
To evaluate the repairment of graphene/β-tricalcium phosphate (G/β-TCP) composite scaffold on cartilage defect in rabbit knee joint.
Method
The G/β-TCP composite scaffold was prepared and the chemical morphology of G/β-TCP composite was observed by X-ray diffraction (XRD) and scanning electron microscope. The pore size analysis and biomechanical test were performed to test the properties of the material. The composite material containing BMSCs was surgically implanted into the femoral condyle of a full-thickness cartilage defect model in rabbits, and the β-TCP material was used as the control. The visceral tissues of the animals were collected at 2, 4, 8, and 16 weeks, and the pathological changes were observed by HE staining to evaluate the biocompatibility of the material. The G/β-TCP composite material containing BMSCs was implanted into the femoral condyle of rabbit full-thickness cartilage defect model, and β-TCP material was used as control. Creatinine (Cr), alanine aminotransferase (ALT), and C-reactive protein (CRP) were detected by ELISA, and the pathological changes were observed by HE staining. Immunohistochemistry assay was used to detect the expression of type I and II collagen in the transplanted cartilage tissue. Toluidine blue staining was used to observe the growth of cartilage.
Results
XRD showed that no difference on the X-ray diffraction characteristics was observed between G/β-TCP and β-TCP. The biomechanical test showed that the graphene doped β-TCP material processed higher mechanical strength. Scanning electron microscopy showed that the surface of G/β-TCP material was smoother and the texture was denser. The scaffold combined with BMSCs was transplanted into the full-thickness cartilage defect rabbit model and the results showed that the serum CRP level increased only at 1 month after implantation, and the Cr level increased at 2 months after implantation, while G/β-TCP material showed rare significant pathological changes on the liver, spleen, kidney, brain, and soft tissue around the operation, which indicated a promising biocompatibility. The expression of type I and II collagen in the cartilage tissue of G/β-TCP treated rabbits was dramatically elevated compared to β-TCP at 2 and 3 months after implantation.
Conclusion
G/β-TCP composite scaffold facilitated the repairment of cartilage defect in rabbit knee joint.
Adsorption of phosphate in aqueous solution by ash from the fruit peel of Caryocar Coriaceum WITTM: Characteristics and adsorption behavior
Authors: Filho francisco José De Paula , Teixeira Yago Neco , Bacurau Vinícius Pereira , Fan Anderson Zhong , Menezes Jorge Marcell Coelho , Oliveira Thiago Mielle Brito Ferreira , Teixeira Raimundo Nonato Pereira , Coutinho Henrique Douglas Melo , Nascimento Ronaldo Ferreira do 
Published: March 2023

Abstract
High phosphate concentrations in water may disturb the ecological balance, deteriorate water quality, cause water eutrophication and affect the smart and sustainable use of water in human activities. With that in mind, the goal of this work was to study the adsorptive capacity of pequi peel ash (PPA) and its efficiency in the removal of phosphate (PO43−) from aqueous solutions, while measuring the kinetics, equilibrium and thermodynamics of the process. The pequi is the fruit of the species Caryocar coriaceum WITTM and is widely found in the Cariri region, in the state of Ceará, Brazil. The processing of this fruit generates a large amount of waste, especially the fruit´s peel, which lacks any further use. These peels were used and tested in this study as raw material for the production of a bioadsorbent. PPA were produced at 500°C in an oxidative atmosphere. The XRF and EDS analysis of PPA after contact with an aqueous PO43− solution confirmed an increase of PO43− content from 1.5–3.7%, thus confirming the adsorption of PO43−. The Elovich and Langmuir models adequately described the kinetics and the equilibrium state of the process, respectively. The highest PO43− adsorption capacity was approximately 79.50 mg g− 1 at 10°C. PO43− adsorption by pequi peel ash is a spontaneous, favorable and exothermic process with structural changes. The highest removal efficiency was 97.08% for a PO43− concentration of 100 mg L− 1. Therefore, PPA has shown potential as an excellent natural bioadsorbent.
Intelligent algorithms in privacy-preserving authentication schemes and traceability with accuracy in VANETs for smart transportation
Authors: Shikka Rishi , R Kamalraj , SHAH PRADEEP KUMAR , Sutariya Kamal , Anwar Syed Rashid , Kumar Arvind 
Published: March 2023

Abstract
Vehicle Adhoc Network is used on the road, where vehicles serve as mobile nodes. VANET's primary uses include intelligent transportation and active security. The framework for intelligent transportation systems (ITS) relies heavily on VANETs. Intelligent Transportation Networks are sometimes used to refer to VANETs. In VANETs, however, authentication and user privacy remain crucial issues. This study proposes a novel method for privacy-based authentication algorithms that improve the accuracy of data transmission for smart VANET transportation. Here, a lightweight hybrid authentication-based privacy-preserving algorithm is used to improve privacy. Then, an effective congestion-based clustering algorithm is used to send the data. Throughput, QoS, latency, computational cost, and data transmission rate are the focus of the experimental analysis. Throughput, QoS, latency, computational cost, and data transmission rate were all achieved using the proposed method. The proposed method makes use of lightweight, efficient pseudonyms that can be used for both message authentication and as a trapdoor to provide conditional anonymity. The proposed method's ability to withstand a variety of security and privacy threats is demonstrated by the various attack scenarios we present.the proposed technique attained throughput 93%, QoS 55%, latency 62%, computational cost 63%, data transmission rate 69%.