bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evolution of the thermodynamic properties of a coronal mass ejection in the inner Corona
Authors: Sheoran Jyoti , Pant Vaibhav , Patel Ritesh , Banerjee Dipankar 
Published: February 2023

The thermodynamic evolution of Coronal Mass Ejections (CMEs) in the inner corona (≤1.5 Rsun) is not yet completely understood. In this work, we study the evolution of thermodynamic properties of a CME core observed in the inner corona on 20 July 2017, by combining the MLSO/K-Cor white-light and the MLSO/CoMP Fe XIII 10747 Å line spectroscopic data. We also estimate the emission measure weighted temperature (TEM) of the CME core by applying the Differential Emission Measure (DEM) inversion technique on the SDO/AIA six EUV channels data and compare it with the effective temperature (Teff) obtained using Fe XIII line width measurements. We find that the Teff and TEM of the CME core show similar variation and remain almost constant as the CME propagates from ∼1.05 to 1.35 Rsun. The temperature of the CME core is of the order of million-degree kelvin, indicating that it is not associated with a prominence. Further, we estimate the electron density of this CME core using K-Cor polarized brightness (pB) data and found it decreasing by a factor of ∼3.6 as the core evolves. An interesting finding is that the temperature of the CME core remains almost constant despite expected adiabatic cooling due to the expansion of the CME core, which suggests that the CME core plasma must be heated as it propagates. We conclude that the expansion of this CME core behaves more like an isothermal than an adiabatic process.
Efficacy of pericapsular nerve group block vs. fascia iliaca compartment block for Hip surgeries: A systematic review and meta-analysis
Authors: Ying Haifeng , Chen Lingyang , Yin Danyang , Ye Yongqing , Chen Jian 
Published: February 2023

ObjectiveThe review aimed to compare outcomes of pericapsular nerve group block (PENG) vs. fascia iliaca compartment block (FICB) for patients undergoing hip surgeries.MethodsRandomized controlled trials (RCTs) published in the databases of PubMed, CENTRAL, Embase, and Web of Science comparing PENG vs. FICB for pain control after hip surgeries were included in the review.ResultsSix RCTs were included. 133 patients received PENG block and were compared with 125 patients receiving FICB. Our analysis showed no difference in 6 h (MD: −0.19 95% CI: −1.18, 0.79 I2 = 97% p = 0.70), 12 h (MD: 0.04 95% CI: −0.44, 0.52 I2 = 72% p = 0.88) and 24 h (MD: 0.09 95% CI: −1.03, 1.21 I2 = 97% p = 0.87) pain scores between PENG and FICB groups. Pooled analysis showed that mean opioid consumption in morphine equivalents was significantly less with PENG as compared to FICB (MD: −8.63 95% CI: −14.45, −2.82 I2 = 84% p = 0.004). Meta-analysis of three RCTs showed no variation in the risk of postoperative nausea and vomiting in the two groups. The quality of evidence on GRADE was mostly moderate.ConclusionModerate quality of evidence suggests that PENG may result in better analgesia than FICB in patients undergoing hip surgeries. Data on motor-sparing ability and complications are scarce to draw conclusions. Further large-scale and high-quality RCTs should be conducted to supplement current findings.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD42022350342.
Global research trends on platelet-rich plasma for tendon and ligament injuries from the past two decades: A bibliometric and visualized study
Authors: Xu Jie , Du Wanli , Xue Xiali , Chen Meng , Zhou Wenqi , Luo Xiaobing 
Published: February 2023

BackgroundIn sports medicine, tendon and ligament injuries are the most prevalent conditions, and with the booming of sports competition, the incidence of sports injuries is gradually increasing, investigating more potent therapeutic options is therefore becoming increasingly crucial. Platelet-rich plasma therapy has gained popularity as an effective and secure treatment in recent years. Currently, a faceted systematic and clear visual analysis is lacking in this research area.MethodsThe literature related to using platelet-rich plasma to treat ligament and tendon injuries from 2003 to 2022 in the core dataset of the Web of Science database was collected and analyzed visually using Citespace 6.1 software. Research hotspots and development trends were analyzed in terms of high-impact countries or regions, authors, research institutions, keywords, and cited literature.ResultsThe literature comprised a total of 1,827 articles. The annual publication volume of relevant literature has demonstrated a significant development tendency as the field of platelet-rich plasma research for tendon and ligament injuries has heated up in recent years. With 678 papers, the United States came in top place, followed by China with 187 papers. Hosp Special Surg ranked first with 56 papers. The hot research topics analyzed by keywords were tennis elbow, anterior cruciate ligament, rotator cuff repair, achilles tendon, mesenchymal stem cells, guided tissue regeneration, network meta analysis, chronic patellar tendinopathy, and follow up.ConclusionAnalysis of the research literature over the past 20 years shows that the United States and China will continue to dominate in terms of volume of publications based on annual volume and trends, with some collaboration among high-impact authors and further collaboration still needed in different countries and institutions. Platelet-rich plasma is widely used in the treatment of tendon ligament injuries. Its clinical efficacy is influenced by a number of factors, the main ones being the inconsistency in the preparation and composition of platelet-rich plasma and its related preparations, and the differences in efficacy due to different activation methods of platelet-rich plasma, as well as factors such as injection time, injection site, administration method, number of administrations, acidity and evaluation methods, In addition, the applicability to different injury diseases remains controversial. In recent years, the molecular biology of platelet-rich plasma for tendon ligament therapy has received increasing attention.
Novel p22 and p30 dual-proteins combination based indirect ELISA for detecting antibodies against African swine fever virus
Authors: Li Jianda , Jiao Jian , Liu Na , Ren Sufang , Zeng Hao , Peng Jun , Zhang Yuyu , Guo Lihui , Liu Fei , Lv Tingting , Chen Zhi , Sun Wenbo , Hrabchenko Nataliia , Yu Jiang , Wu Jiaqiang 
Published: February 2023

IntroductionAfrican swine fever virus (ASFV) infection is one of the most complex and fatal hemorrhagic viral diseases, causing a devastating loss to the swine industry. Since no effective vaccine is available, prevention and control of ASFV heavily depends on early diagnostic detection.MethodsIn this study, a novel indirect ELISA was established for detecting antibodies against ASFV using dual-proteins, p22 and p30. Recombinants p22 and p30 were expressed and purified from E.coli vector system by recombined plasmids pET-KP177R and pET-CP204L. p22 and p30 were mixed as antigens for developing the indirect ELISA.ResultsThrough optimizing coating concentrations of p30 and p22, coating ratio (p30: p22 = 1:3), and serum dilution (as 1:600), the established ELISA performed higher specificity, sensitivity, and repeatability against ASFV-positive serum. Furthermore, 184 clinical serum samples from suspected diseased pigs were verified the established ELISA in clinical diagnosis. The results showed that compared with two commercial ELISA kits, the established ELISA possessed higher sensitivity and almost uniform coincidence rate.ConclusionThe novel indirect ELISA based on dual-proteins p30 and p22 performed a valuable role in diagnostic detection of ASFV, providing a broad insight into serological diagnostic methods of ASFV.
Renal Vessel Extension With Cryopreserved Vascular Grafts: Overcoming Surgical Pitfalls in Living Donor Kidney Transplant
Authors: Fallani Guido , Maroni Lorenzo , Bonatti Chiara , Comai Giorgia , Buzzi Marina , Cuna Vania , Vasuri Francesco , Caputo Francesca , Prosperi Enrico , Pisani Federico , Pisillo Beatrice , Maurino Ludovica , Odaldi Federica , Bertuzzo Valentina Rosa , Tondolo Francesco , Busutti Marco , Zanfi Chiara , Del Gaudio Massimo , La Manna Gaetano , Ravaioli Matteo 
Published: February 2023

In LDKT, right kidneys and kidneys with anomalous vascularization are often deferred because of concerns on complications and vascular reconstructions. To date, only few reports have examined renal vessel extension with cryopreserved vascular grafts in LDKT. The aim of this study is to investigate the effect of renal vessel extension on short-term outcomes and ischemia times in LDKT. From 2012 to 2020, recipients of LDKT with renal vessels extension were compared with standard LDKT recipients. Subset analysis of rights grafts and grafts with anomalous vascularization, with or without renal vessel extension, was performed. Recipients of LDKT with (n = 54) and without (n = 91) vascular extension experienced similar hospital stays, surgical complications and DGF rates. For grafts with multiple vessels, renal vessel extension granted a faster implantation time (44±5 vs. 72±14 min), which resulted comparable to that of standard anatomy grafts. Right kidney grafts with vascular extension had a faster implantation time compared to right kidney grafts without vascular lengthening (43±5 vs. 58±9 min), and a comparable implantation time to left kidney grafts. Renal vessel extension with cryopreserved vascular grafts allows faster implantation time in right kidney grafts or grafts with anomalous vascularization, maintaining similar surgical and functional outcomes.
Subtypes of Adult-Onset Asthma at the Time of Diagnosis: A Latent Class Analysis
Authors: Mäkikyrö Elina M. S. , Jaakkola Maritta S. , Lajunen Taina K. , Malmberg L. Pekka , Jaakkola Jouni J. K. 
Published: February 2023

Introduction: Only a few previous studies have investigated the subtypes of adult-onset asthma. No previous study has assessed whether these subtypes are different between men and women, or whether these subtypes have different risk factors. Methods: We applied latent class analyses to the Finnish Environment and Asthma Study population, including 520 new cases of adult-onset asthma. We formed subtypes separately between women and men and analyzed the following determinants as potential predictors for these subtypes: age, body mass index, smoking, and parental asthma. Results: Among women, the subtypes identified were: 1. Moderate asthma, 2. Cough-variant asthma, 3. Eosinophilic asthma, 4. Allergic asthma, and 5. Difficult asthma. Among men, the subtypes were: 1. Mild asthma, 2. Moderate asthma, 3. Allergic asthma, and 4. Difficult asthma. Three of the subtypes were similar among women and men: Moderate, Allergic, and Difficult asthma. In addition, women had two distinct subtypes: Cough-variant asthma, and Eosinophilic asthma. These subtypes had different risk factor profiles, e.g., heredity was important for Eosinophilic and Allergic asthma (RR for Both parents having asthma in Eosinophilic 3.55 (1.09 to 11.62)). Furthermore, smoking increased the risk of Moderate asthma among women (RR for former smoking 2.21 (1.19 to 4.11)) and Difficult asthma among men but had little influence on Allergic or Cough-variant asthma. Conclusion: This is an original investigation of the subtypes of adult-onset asthma identified at the time of diagnosis. These subtypes differ between women and men, and these subtypes have different risk factor profiles. These findings have both clinical and public health importance for the etiology, prognosis, and treatment of adult-onset asthma.
Studies on the Oxidation of Aromatic Amines Catalyzed by Trametes versicolor Laccase
Authors: Bassanini Ivan , Grosso Simone , Tognoli Chiara , Fronza Giovanni , Riva Sergio 
Published: February 2023

The bio-oxidation of a series of aromatic amines catalyzed by T. versicolor laccase has been investigated exploiting either commercially available nitrogenous substrates [(E)-4-vinyl aniline and diphenyl amine] or ad hoc synthetized ones [(E)-4-styrylaniline, (E)-4-(prop-1-en-1-yl)aniline and (E)-4-(((4-methoxyphenyl)imino)methyl)phenol]. At variance to their phenolic equivalents, the investigated aromatic amines were not converted into the expected cyclic dimeric structures under T. versicolor catalysis. The formation of complex oligomeric/polymeric or decomposition by-products was mainly observed, with the exception of the isolation of two interesting but unexpected chemical skeletons. Specifically, the biooxidation of diphenylamine resulted in an oxygenated quinone-like product, while, to our surprise, in the presence of T. versicolor laccase (E)-4-vinyl aniline was converted into a 1,2-substited cyclobutane ring. To the best of our knowledge, this is the first example of an enzymatically triggered [2 + 2] olefin cycloaddition. Possible reaction mechanisms to explain the formation of these products are also reported.
Gata2a Mutation Causes Progressive Microphthalmia and Blindness in Nile Tilapia
Authors: Liu Xingyong , Zhou Li , Li Wenbo , Wu Jiahong , Wang Deshou 
Published: February 2023

The normal development of lens fiber cells plays a critical role in lens morphogenesis and maintaining transparency. Factors involved in the development of lens fiber cells are largely unknown in vertebrates. In this study, we reported that GATA2 is essential for lens morphogenesis in Nile tilapia (Oreochromis niloticus). In this study, Gata2a was detected in the primary and secondary lens fiber cells, with the highest expression in primary fiber cells. gata2a homozygous mutants of tilapia were obtained using CRISPR/Cas9. Different from fetal lethality caused by Gata2/gata2a mutation in mice and zebrafish, some gata2a homozygous mutants of tilapia are viable, which provides a good model for studying the role of gata2 in non-hematopoietic organs. Our data showed that gata2a mutation caused extensive degeneration and apoptosis of primary lens fiber cells. The mutants exhibited progressive microphthalmia and blindness in adulthood. Transcriptome analysis of the eyes showed that the expression levels of almost all genes encoding crystallin were significantly down-regulated, while the expression levels of genes involved in visual perception and metal ion binding were significantly up-regulated after gata2a mutation. Altogether, our findings indicate that gata2a is required for the survival of lens fiber cells and provide insights into transcriptional regulation underlying lens morphogenesis in teleost fish.
ADHD Follow-Up in Adulthood among Subjects Treated for the Disorder in a Child and Adolescent Mental Health Service from 1995 to 2015
Authors: Di Lorenzo Rosaria , Balducci Jessica , Cutino Anna , Latella Emanuela , Venturi Giulia , Rovesti Sergio , Filippini Tommaso , Ferri Paola 
Published: February 2023

Background and Objectives: ADHD is a neurodevelopmental disorder characterized by inattention and hyperactivity/impulsivity and can persist in adulthood. The aim of this study is to deepen knowledge about adult ADHD follow-up. Materials and Methods: This observational study consists of one retrospective part aimed at collecting records of children and adolescents treated for ADHD in the Children and Adolescent Mental Health Service (CAMHS) from 1995 to 2015 and, successively, at identifying their adult follow-up in Adult Mental Health Service (AMHS); the second part consists of ADHD scale administration, Diagnostic Interview for ADHD in Adults (DIVA 2-0) and Adult Self Rating Scale (ASRSv1.1), for the subjects currently being treated at AMHS who agreed to participate in the study. Results: We observed that among the 55 patients treated at CAMHS between 1995 and 2015 for ADHD and subsequently at the AMHS, none presented a diagnosis of ADHD; instead, they were treated for Intellectual Dysfunction (33%), Borderline Personality Disorder (15%) and Anxiety Disorders (9%), and two individuals were also diagnosed with comorbid substance/alcohol abuse (4%). Of the 55 patients, only 25 (45%) were treated at AMHS during the study period. Though we asked for their informed consent to administer the questionnaires, we were able to test only seven patients. The ASRS-V1.1 score showed that 43% of patients reported symptoms of ADHD persistence in adulthood. For DIVA 2.0, 57% of individuals reported scores indicating the persistence of the ADHD inattention component, and 43% the persistence of both ADHD dimensions. Conclusions: ADHD cannot be considered a disorder confined to childhood/adolescence but instead is a chronic and complex condition that can persist into adulthood. The very small size of our final sample may account for both the high ADHD dropout rate over the long follow-up period and the difficult transition from child to adult health care in ADHD treatment. Our investigation suggests the need for specific training in the diagnosis and treatment of adult ADHD and the implementation of transition protocols between minor and adult services to improve long-term treatments.
Effect of Cr on the Microstructure and Mechanical Properties of the Al-Cu-Y-Zr Alloy
Authors: Amer Sayed M. , Glavatskikh Maria V. , Barkov Ruslan Yu. , Loginova Irina S. , Pozdniakov Andrey V. 
Published: February 2023

The present investigation aimed at the determination of Cr addition on microstructure, phase composition, and mechanical properties of the Al-Cu-Y-Zr alloy. Quasi-binary alloys of the ternary Al-Cu-Y system with atomic rotation of Cu/Y = 4/1 have a narrow solidification range with high solidus temperature. The addition of 0.3% Cr in the Al-5.1Cu-1.7Y-0.3Zr alloy provides a formation of a novel quaternary Al81–85Cu7–10Y3–4Cr5 phase. L12-Al3(Zr,Y) phase spherical particles with a diameter of 50 nm were nucleated during solution treatment at 600 °C. Al7Cr precipitates were not found in the microstructure. The main strengthening effect of 32.4 MPa and 29.1 MPa was achieved from L12 and θ’(Al2Cu) precipitates, respectively, in accordance with the calculation. The calculated hardness of 61.5HV based on the calculated σy is consistent with the experimental value of hardness. Al3Zr and Al7Cr phases should be in equilibrium with (Al) in accordance with the calculated polythermal section. However, transmission electron microscopy investigation demonstrates the Al3(Zr,Y) precipitates only. As a result, the dissolved Cr atom provides a slightly higher hardness in the rolled and annealed AlCuYZrCr alloy. A suitable combination of strength and ductility was observed both after rolling and after rolling with subsequent annealing at 150 °C for 3 h—the alloy exhibited a yield strength of 308–315 MPa, an ultimate tensile strength of 323–335 MPa, and an elongation to failure of 2.0–3.3%.
A Microstrip Antenna Using I-Shaped Metamaterial Superstrate with Enhanced Gain for Multiband Wireless Systems
Authors: Ajewole Bukola , Kumar Pradeep , Afullo Thomas 
Published: February 2023

This paper presents the design of a rectangular microstrip patch antenna (MPA) using the I-shaped metamaterial (MTM) superstrate. A seven × seven array of the I-shaped MTM unit cell is used as the superstrate to enhance the antenna performance. The antenna is fed by a microstrip feeding technique and a 50 Ω coaxial connector. An in-phase electric field area is created on the top layer of the superstrate to improve the performance of the antenna. The proposed I-shaped MTM-based rectangular MPA produces three operating frequencies at 6.18 GHz, 9.65 GHz, and 11.45 GHz. The gain values of the proposed antenna at 6.18 GHz, 9.65 GHz and 11.45 GHz are 4.19 dBi, 2.4 dBi, and 5.68 dBi, respectively. The obtained bandwidth at frequencies 6.18 GHz, 9.65 GHz and 11.45 GHz are 240 MHz (3.88%), 850 MHz (8.8%), and 1010 MHz (8.82%), respectively. The design and simulation of the antenna are done using the Computer Simulation Technology (CST) studio suite and MATLAB. The proposed I-shaped MTM-based rectangular MPA is fabricated on a low-cost FR-4 substrate and measured using the Agilent 8719ET network analyzer. The proposed antenna has an overall dimension of 70 × 70 × 1.6 mm3. A significant improvement in the gain of the antenna up to 74.28% is achieved. The obtained results confirm that the proposed multiband antenna has a high gain, and enhancement in bandwidth and radiation efficiency. These properties make the proposed antenna suitable for the multiband wireless communications systems such as Wi-Fi devices, radar systems, short- and long-range tracking systems, etc.
Radiative Effects and Costing Assessment of Arctic Sea Ice Albedo Changes
Authors: Hao Hairui , Su Bo , Liu Shiwei , Zhuo Wenqin 
Published: February 2023

The rapid loss of Arctic Sea ice cover and thickness diminishes the surface albedo, which increases the ocean’s absorption of solar heat and exacerbates the Arctic amplification effect. According to the most recent research from the Intergovernmental Panel on Climate Change, the Sixth Assessment Report (IPCC, AR6), the extent of summer sea ice is anticipated to decrease below 1 million km2 by the 2050s as a result of the extreme climate. Nevertheless, past and future changes in sea ice albedo radiative forcing and the resulting economic cost remain to be explored in systematic and multi-disciplinary manners. In this study, we first analyze the evolution of Arctic sea ice radiative forcing (SIRF) from 1982 to 2100 using a radiative kernel method based on albedo data from the Polar Pathfinder-Extent (APP-x) and Coupled Model Intercomparison Project 5 (CMIP5). Then, the SIRF is converted to CO2 equivalent emissions via the Dynamic Integrated Model of Climate and Economy (DICE) model. Finally, the associated costs are calculated using the substitute cost method, based on the social cost of carbon to achieve the Paris Agreement targets. The results show that the average Arctic SIRF was −0.75 ± 0.1 W·m−2 between 1982 and 2020, and increased by 0.12 W·m−2 during this period. The SIRF in April–June accounts for nearly 77% of the average annual value, with a maximum absolute value of –3.2 W·m−2 in May. Through model transformation, it is shown that the Arctic SIRF rising leads to global warming comparable to the effect of an increase of 34.5 Gt of CO2 in the atmosphere relative to pre-industrialization, and results in a loss of 24.4–48.8 trillion USD for climate regulation service (CRS). From 2020 to 2100, in the representative concentration pathway (RCP) 8.5, the Arctic SIRF is projected to increase by 0.31 W·m−2. Combined with the discount rate, the estimated average annual cost over the period ranges from 6.7–13.3 trillion USD. These findings provide a systematic understanding of the radiative effect of Arctic sea ice change on the global climate and the corresponding economic cost.