bluuebunny/crossref_metadata_2025_split huggingface dataset:
COMPARATIVE STUDY OF CISATRACURIUM AND ATRACURIUM IN DIFFERENT DOSES FOR INTUBATION DURING GENERAL ANESTHESIA IN LOWER ABDOMINAL SURGERY: A PROSPECTIVE RANDOMIZED DOUBLE-BLIND INTERVENTIONAL TRIAL
Authors: GURJAR VEERENDRA SINGH , LALL TARUN , MEENA SURENDRA 
Published: July 2023

Objective: General anesthesia requires smooth endotracheal intubation, aided by neuromuscular blocking agents. Atracurium and cis-atracurium are non-depolarizing agents used for muscle relaxation. Succinylcholine, though effective, has undesirable side effects. This study aims to compare atracurium and different doses of cis-atracurium to assess their onset, duration, recovery, hemodynamic effects, and side effects, in order to identify the ideal agent for intubation.
Methods: The study will compare atracurium (0.5 mg/kg) with two different doses of cis-atracurium, namely 0.10 mg/kg and 0.15 mg/kg. The parameters evaluated will include the onset of neuromuscular blockade, duration of blockade, recovery time, hemodynamic effects, and incidence of side effects. Neuromuscular monitoring will be employed to ensure proper dosing and prevent residual paralysis.
Results: The study will provide valuable data on the comparative characteristics of atracurium and cis-atracurium at different doses. This includes their onset of action, duration of neuromuscular blockade, recovery time, impact on hemodynamic parameters, and occurrence of side effects. The results will shed light on the efficacy, safety, and tolerability of these drugs for endotracheal intubation.
Conclusion: The study aims to identify the most suitable neuromuscular blocking agent for facilitating endotracheal intubation by comparing atracurium and different doses of cis-atracurium. By assessing their onset, duration, recovery time, hemodynamic effects, and side effect profiles, clinicians can make informed decisions to optimize patient care during general anesthesia.
Penerapan Tema Green Architecture pada Agrowisata Kopi Arabika di Desa Belantih, Kintamani
Authors: I Gede Soemantaranatha Eka Putra Wiratenaya  , Agus Kurniawan  , Ni Wayan Nurwarsih  
Published: July 2023

Agrowisata adalah sebagai upaya pendidikan nonformal bagi masyarakat setempat sekaligus wisatawan yang melakukan kunjungan wisata. Pembelajaran yang berlangsung pada agrowisata sangat dibutuhkan sebab dapat menunjang proses belajar yang dilakukan di sekolah untuk mendalami pembelajaran serta berdampak pada peningkatan pemahaman akademik. Kopi arabika kintamani dari segi kualitas dan cita rasa dari telah diakui oleh negara penikmat kopi di dunia. Desa Belantih yang berada di Kecamatan Kintamani merupakan salah satu penghasil kopi arabika, yang dimana setiap Banjar/Dusun terdapat Subak Abian dan kelompok tani yang mengatur kegiatan usaha tani kopi arabika salah satunya ialah kelompok tani Dharma Kria. Kelompok tani Dharma Kria merupakan kelompok tani yang berada di Banjar Luahan, Desa Belantih yang terbentuk pada 2015 dengan jumlah anggotanya 34 orang. Pada era sekarang, di Bali kopi semakin banyak dinikmati oleh berbagai kalangan. Eksistensi kopi di Bali yang semakin meningkat terlihat dari fasilitas kedai-kedai kopi di Bali khusunya di Kecamatan Kintamani yang semakin bertambah namun, masih banyak yang kurang mengerti mengenai kopi arabika kintamani. Fasilitas yang menyediakan edukasi dan rekreasi yang dapat dijangkau oleh berbagai kalangan sangat diperlukan untuk mewadahi wisatawan yang ingin lebih mempelajari proses biji kopi arabika kintamani mulai dari sejarah kopi arabika kintamani, penanaman, pemetikan, pengolahan, dan penyajian kopi arabika itu sendiri. Kegiatan rekreasi dapat dilakukan dengan menyebar fasilitas edukasi di beberapa titik agar wisatawan merasakan sensasi berjalan di tengah-tengah areal perkebunan kopi warga yang memiliki hawa sejuk. Metode pengumpulan data yang digunakan dalam antara lain studi literatur, observasi lapangan, dan survey
Redesain Pusat Konservasi Dan Edukasi Penyu Di Desa Serangan, Bali
Authors: Narayana Pramantya , Mertawijaya I Kadek , Parwata I Wayan 
Published: July 2023

Desa Serangan terletak di Kecamatan Denpasar Selatan, desa Serangan termasuk salah satu wilayah yang memiliki potensi sumber daya kelautan. Penyu adalah satwa yang bermanfaat bagi kehidupan manusia, jika dikembangbiakan. Manfaat tersebut mencakup aspek peningkatan pertumbuhan ekonomi melalui sektor perikanan, menjaga keseimbangan mata rantai ekosistem, ilmu pengetahuan, pengembangan wisata edukasi. Pusat Konservasi Dan Edukasi Penyu merupakan suatu upaya untuk masyarakat pesisir pantai di Desa Serangan sebagai media edukasi terhadap peran masyarakat dalam menjaga dan melindungi ekosistem habitat penyu di Desa Serangan. Konservasi dan Edukasi Penyu ini dibentuk untuk menyelamatkan penyu dari pembantaian, perdagangan maupun konsumsi masyarakat lokal terkait kendala dan strategi adaptasi pada musim yang berbeda. Pada pusat konservasi dan edukasi penyu terdapat beberapa permasalahan yaitu: sistem zonasi, perletakan ruang, sirkulasinya, bangunan yang telah usang, dan material bangunan yang kurang layak sehingga perlu di redesain agar memenuhi kebutuhan pengunjung. Redesain ini menerapkan konsep Nature In Space yang diartikan alam dalam ruang dengan Tema Arsitektur Biophilic agar pengunjung yang datang dapat mereduksi stress dan merasa nyaman berada pada fasilitas ini.
Analisis Sistem Pengendalian Intern Terhadap Kredit Macet Bank Perkreditan Rakyat (BPR) Kota Jambi
Authors: Arum R Dwi , Wahyudi Ilham , Wijaya R Rico 
Published: July 2023

Penelitian ini bertujuan untuk melihat bagaimana sistem pengendalian intern terhdapa kredit macet pada Bank Perkreditan Rakyat di Kota Jambi. Sistem pengendalian diukur dengan menggunakan skala simantic differensial dengan interval 1-7 dan kredit macet diukur dengan skala rasio.Penelitian ini menggunakan sampel perusahaan Bank Perkreditan Rakyat yang terdaftar di OJK dan yang berada di wilayah Kota Jambi. Teknik pengemabilan sampel yang digunakan teknik sampling jenuh, sampel yang digunakan 14 perusahaan dengan total 140 responden. Teknik analisis data dalam penelitian ini adalah statistik deskriptif dan analisis regresi linear berganda. Software yang digunakan untuk olah data adalah SPSS versi 22 for windows. Hasil pengujian hipotesis sebagai berikut. Pertama, untuk mengetahui bagaimana sistem pengendalian intern terhadap kredit macet pada Bank Perkreditan Rakyat di Kota Jambi. Kedua, melihat pengaruh sistem pengendalian intern terhadap kredit macet pada Bank Perkreditan Rakyat di Kota Jambi.
Beberapa Tumbuhan yang Berpotensi Sebagai Anti-Skabies di Indonesia
Authors: Septiani Linda , Pertiwi Primasari , Andrifianie Femmy , Marcellia Selvi , Damayanti Ervina 
Published: July 2023

Scabies is a type of parasitic infectious disease of the skin caused by the mite Sarcoptes scabiei var hominis. Scabies is often found in areas with high population density, low economic status, poor sanitation and hygiene. For now, medication is one of the factors inhibitors in the treatment of scabies. This happened because chemical drugs has several effects such as contraindications, irritation, toxicity, and is not effective to all mite stages. Therefore, alternative treatments are needed that come from natural ingredients by exploring various plants in Indonesia that potential to have an active compounds to eradicate mites. The aims of this study is to summarize some of the result of research on alternative plant based anti-scabies and give the information as a reference for further research. This study uses the literature study method to obtain information from several research journal. Based on the results of a literature search, it was found that 15 plant species were extracted and tested on animals and humans which contain active compounds and have the potential as anti-scabies. These fifteen plants can grow well in the territory of Indonesia, so that people can cultivate them and develop them as natural anti-scabies agents. AbstrakSkabies merupakan salah satu jenis penyakit infeksi parasit pada kulit yang disebabkan oleh tungau Sarcoptes scabiei var hominis. Skabies banyak ditemukan di daerah dengan kepadatan penduduk yang tinggi, status ekonomi rendah, sanitasi dan hygiene yang buruk. Saat ini, pengobatan dengan bahan kimia menjadi salah satu faktor yang menjadi penghambat dalam penanggulangan skabies. Hal tersebut terjadi karena obat kimia memiliki beberapa efek seperti kontraindikasi, iritasi, toksik, dan tidak efektif terhadap semua stadium tungau. Oleh karena itu, diperlukan alternatif pengobatan yang berasal dari bahan alam dengan mengeksplorasi berbagai tumbuhan di Indonesia yang berpotensi memiliki senyawa aktif untuk membasmi tungau. Tujuan studi ini adalah merangkum beberapa hasil penelitian tentang obat alternatif anti skabies berbahan dasar tumbuhan dan memberikan informasi dasar sebagai referensi penelitian lebih lanjut. Penelitian ini menggunakan metode studi literatur untuk memperoleh informasi dari beberapa jurnal penelitian. Berdasarkan hasil penelusuran pustaka diperoleh 15 jenis tumbuhan yang di ekstrak dan di uji ke hewan maupun manusia yang memiliki kandungan senyawa aktif dan berpotensi sebagai anti skabies. Kelima belas tanaman tersebut dapat tumbuh dengan baik dengan di wilayah Indonesia, sehingga masyarakat dapat membudidayakannya dan mengembangkannya sebagai bahan anti-skabies alami.
Сознание: между психопатией и шизофренией
Authors: Мерзляков Сергей 
Published: July 2023

Вопрос о функции сознания является частью «трудной проблемы сознания» и фокусирует внимание на гипотетической роли феноменальных данных, то есть на определении момента актуализации сознания. В настоящее время не существует общепризнанных представлений о том, какую роль сознание играет в жизни человека. Дискуссионными являются вопросы об эволюционной причине появления сознания и распространении сознания среди отличных от человека объектов мира. При этом в теории сознания недостаточно внимания уделяется вопросу о степени реализации функции сознания. Допустимо, что гипотетическая функция сознания может по-разному реализовываться у людей. Подобная постановка вопроса позволяет внести коррективы в методологию поиска физиологических коррелятов сознательных действий; под другой оптикой посмотреть на проблему нечеловеческих носителей сознания; выйти в пространство этических дискуссий. В статье обосновывается потенциал исследовательского движения в этом направлении изучения сознания на примере воображения как гипотетической функции сознания.
Ключевые слова: сознание, воображение, трудная проблема сознания, психопатия, шизофрения, функция сознания
Аннотация
Вопрос о функции сознания является частью «трудной проблемы сознания» и фокусирует внимание на гипотетической роли феноменальных данных, то есть на определении момента актуализации сознания. В настоящее время не существует общепризнанных представлений о том, какую роль сознание играет в жизни человека. Дискуссионными являются вопросы об эволюционной причине появления сознания и распространении сознания среди отличных от человека объектов мира. При этом в теории сознания недостаточно внимания уделяется вопросу о степени реализации функции сознания. Допустимо, что гипотетическая функция сознания может по-разному реализовываться у людей. Подобная постановка вопроса позволяет внести коррективы в методологию поиска физиологических коррелятов сознательных действий; под другой оптикой посмотреть на проблему нечеловеческих носителей сознания; выйти в пространство этических дискуссий. В статье обосновывается потенциал исследовательского движения в этом направлении изучения сознания на примере воображения как гипотетической функции сознания.
HUBUNGAN ANTARA KECERDASAN EMOSIONAL TERHADAP KEMANDIRIAN PADA ANAK USIA DINI DALAM RENTAN USIA 4-5 TAHUN
Authors: Nurhikmah Maryam Nurhikmah , Yulianingsih Yuyun , Ratnasih Teti 
Published: July 2023

Penelitian ini bertujuan untuk mengetahui hubungan kecerdasan emosional terhadap kemandirian anak usia dini, khususnya pada aspek perkembangan sosial emosional usia 4̄̄̄̄̄̄̄-5 tahun. Penelitian ini menggunakan metode dan pendekatan kuantitatif korelasional. Subjek dalam penelitian ini adalah Kelompok A di salah satu RA di Kota Bandung yang berjumlah 28 anak. Penelitian ini menggunakan sampel jenuh, yang artinya semua populasi dijadikan sampel. Teknik pengumpul data melalui lembar observasi. Hasil analisis data penelitian menggunakan perhitungan koefisien korelasi Spearman Rank memperoleh hasil hitung 0,91. Sedangkan hasil perhitungan uji signifikansi korelasi menggunakan t test diperoleh nilai thitung = 11,02 dan ttabel taraf signifikansi 5% dengan db = 26 sebesar 2,056. Maka thitung = 11,02 ttabel = 2,056, dan dapat diinterpretasikan bahwa terdapat hubungan yang signifikan antara kecerdasan emosional dengan kemandirian anak usia dini. Selain itu, koefisien determinasi yang diperoleh sebesar 42%. Artinya, kecerdasan emosional memberikan kontribusi sebanyak 42% terhadap kemandirian anak usia dini di salah satu RA di Kota Bandung.
ST-elevation myocardial infarction, severe cardiogenic shock, and myocarditis secondary to leptospirosis: A rare case report
Authors: Sukmagautama Coana , Muhammad Faizal , Maharestri Ken Zuraida , Hanif Ihsan , Myrtha Risalina 
Published: July 2023

Background: Leptospirosis is a bacterial infection that can lead to several organ dysfunctions. However, cardiac involvements in leptospirosis are uncommon findings. The unknown pathogenesis and association between leptospirosis and cardiac involvements can lead to a diagnostic challenge and case rarity. This study aims to report a diagnosis challenge through physical and laboratory examination of a patient with ST-elevation myocardial infarction (STEMI) and myocarditis without common leptospiral-associated organ dysfunction features. We also report the therapeutic strategies in this case, despite its clinical guideline limitation.
Case: A 35-year-old male patient came to the emergency department with flu-like symptoms. Twenty-four hours later, the patient showed acute angina, STEMI, and elevated high-sensitivity cardiac troponin followed by cardiogenic shock without significant modifiable and non-modifiable risk factors for heart diseases. The patient received fibrinolytic, supportive therapy and correction of hemodynamic derangement. We found thrombocytopenia on the second day. Surprisingly, the immunoserology showed positive anti-leptospira IgM and negative anti-dengue IgM and IgG. Further, there was echocardiography suspected myocarditis due to high echogenicity in the left ventricle's basal-apical lateral endocardium. Thus, we diagnosed this case as leptospirosis with cardiac involvement. Direct cardiac tissue damage due to systemic vasculitis, disseminated intravascular coagulation, and pro-inflammatory cytokine storm is believed to be pathomechanism in leptospirosis with cardiac involvement. After diagnosis establishment, his final therapies in the hospital were Aspirin, Atorvastatin, Clopidogrel, Spironolactone, Ramipril, Carvedilol, Omeprazole, Doxycycline, and Ceftriaxone. Subsequently, he was discharged from hospital and continued to receive cardiovascular medications, antibiotics, antiplatelet, potassium-sparing diuretics, and omeprazole.
Conclusion: This case highlights the importance of thorough clinical-laboratory evaluation in a patient with an atypical leptospiral presentation. Although leptospirosis is not a common cause of heart diseases such as STEMI, cardiogenic shock, and myocarditis, we recommend supportive therapy and correction of hemodynamic derangement for leptospirosis with cardiac involvement, in addition to leptospiral antibiotic drug itself.
Prevention of Cardiovascular Disease in the Community Through Walking Intervention: Scoping Review
Authors: Widyawati Widyawati , Rahayuwati Laili , Mambang Sari Citra Windani , Irza Damar 
Published: July 2023

Background: Cardiovascular disease is the number one killer in the world. The SDGs target reducing mortality through cost-effective prevention efforts. Physical activity, including walking, has been proven to prevent cardiovascular disease. Walking is an activity that is cheap, easy, simple, and does not need tools and skills, so it can be done in general by the community. However, the modern world makes people's walking activities low. There is a need to find evidence of walking interventions that can increase walking and prevent cardiovascular disease.
Purpose: This scoping review aims to identify literature focusing on walking interventions that increase footsteps and reduce disease risk to prevent cardiovascular disease.
Methods: Following the guidelines for the JBI scoping review methodology. Articles conducted searches on the Ebscho CINAHL, Academic, PubMed, and ProQuest databases from 2013 to 2021. The collected data were extracted in tabular and narrative form.
Results: Thirteen articles met the criteria involving 2,910 people from eight countries. Eleven studies used a randomized controlled trial, and two used a quasi-experimental design.
Conclusion: Walking interventions that support increased footsteps include: distance, duration per week (< 150 minutes or > 150 minutes), supervision, activities accompanied by socio-cultural activities, counselling, and motivation, in addition to the use of tools such as pedometers, accelerators, and smartwatch is used as a footstep monitor. Intervention in walking is beneficial in reducing cardiovascular diseases risk indicators such as blood pressure, BMI, blood glucose, cholesterol, and triglycerides.
Dialogue: Shorish and Nowviskie
Authors: Shorish Yasmeen , Nowviskie Bethany 
Published: July 2023

This dialogue offers perspectives from two differently-positioned library leaders on their collaborative work to advance equity and racial justice in the context of a predominantly white academic library and educational technology organization. Topics covered include issues of scale and temporality in reckoning with structural racism; developing a workplace culture that supports growth and learning while mitigating harm; building and sustaining community both within and beyond formal institutions; developing personal and organizational accountability; and challenges in the use of data for assessing progress and working authentically toward change.
Pre-print first published online 5/12/2022
Does It Matter
Authors: Ahmed Sumayya , Clemens Rachael , Patillo Ericka , Murillo Angela 
Published: July 2023

The catalytic social justice events of the spring and summer of 2020 led to calls for a racial reckoning within society at large and also within the field of library and information science (LIS). This motivated us to capture the perceptions and voices of professionals across the field about changes they may have witnessed in their workplace, profession, and themselves. We consider the following questions: Have conversations, social spaces, teaching practices, policies, workplace dynamics, and demands, changed in response to the Black Lives Matter (BLM) protests, and if so, how? Have institutional changes perceived as responses to BLM protests been witnessed? What are the nuances behind such behavioral changes (e.g., opportunity, compulsion, peer pressure)?
For this research, we used Critical Incident Technique (CIT) to explore how the 2020 BLM protests impacted the workplace environments of LIS faculty and professionals in libraries, archives, and museums (LAMs). A 27-question survey was administered via Qualtrics and participants were recruited using LAM professional listservs. A total of 645 participants completed the survey. This research provides the preliminary analysis and discussion of those results and provides insights to the impact of the 2020 social justice movements in LAMs.
By capturing voices of LAM professionals, we explore participants’ perceptions of the impact that BLM protests had on their institutions and/or professional associations and document a range of responses at both the individual and structural levels.
Pre-print first published online 9/30/2022
Pharmacokinetics and plasma protein binding of a single dose of clodronate disodium are similar for juvenile sheep and horses
Authors: Vergara-Hernandez Fernando B. , Nielsen Brian D. , Kottwitz Jack J. , Panek Char L. , Robison Cara I. , Paris Brittany L. , Welsh Thomas H. , Bradbery Amanda N. , Leatherwood Jessica L. , Colbath Aimee C. 
Published: July 2023

Abstract

OBJECTIVE
To determine the single-dose pharmacokinetics of clodronate disodium (CLO) in juvenile sheep and the plasma protein binding (PPB) of CLO in juvenile sheep and horses.

ANIMALS
11 juvenile crossbred sheep (252 ± 6 days) for the pharmacokinetic study. Three juvenile crossbred sheep (281 ± 4 days) and 3 juvenile Quarter Horses (599 ± 25 days) for PPB analysis.

METHODS
CLO concentrations were determined using liquid chromatography-mass spectrometry. Pharmacokinetic parameters were calculated by noncompartmental analysis from plasma samples obtained at 0, 0.5, 1, 3, 6, 12, 24, 48, and 72 hours after CLO administered IM at 0.6 mg/kg. PPB was determined using equine and ovine plasma in a single-use rapid equilibrium dialysis system.

RESULTS
The mean and range for maximum plasma concentration (Cmax: 5,596; 2,396–8,613 ng/mL), time of maximal concentration (Tmax: 0.5; 0.5–1.0 h), and area under the curve (AUCall: 12,831; 7,590–17,593 h X ng/mL) were similar to those previously reported in horses. PPB in sheep and horses was moderate to high, with unbound fractions of 26.1 ± 5.1% in sheep and 18.7 ± 7.5% in horses, showing less than a 1.4-fold difference.

CLINICAL RELEVANCE
The pharmacokinetic parameters and PPB of CLO in juvenile sheep were similar to those previously reported in horses. The results suggest that juvenile sheep can be utilized as an animal model for studying the potential risks and/or benefits of bisphosphonate use in juvenile horses.
Hydrothermal synthesis and characterization of calcium phosphate-based coatings on AZ31 magnesium alloy
Authors: Horáková L. , Doskočil L. , Wasserbauer J. , Buchtík M. 
Published: July 2023

Abstract
This study aims to analyze the influence of process parameters used for hydrothermal synthesis of CaP coatings on their properties and to improve their corrosion resistance and biocompatibility compared to the substrat AZ31. The parameters monitored were deposition time, pH of the reaction mixture, and concentration of precursors in the reaction mixture. For the deposited CaP coatings on AZ31 magnesium alloy, the surface morphology and the number of structural defects were evaluated using scanning electron microscopy. Electrochemical corrosion properties were evaluated using polarization techniques in Hank’s solution. The results showed that the best properties were obtained for the sample prepared in a reaction mixture at 120 °C, pH 5 for a deposition time of 120 min, when the concentration of precursors in the reaction mixture was 0.30 mol/l Ca(NO3)2·4H2O and 0.28 mol/l NH4H2PO4. Under these conditions, the best electrochemical corrosion properties were achieved.