bluuebunny/crossref_metadata_2025_split huggingface dataset:
Combined effect of thymectomy on myasthenia gravis in patients with concomitant auto-immune diseases: a 22-year single-center experience
Authors: Liu Lei , Zhang Jiaqi , Guo Chao , Chen Yeye , Liu Hongsheng , Li Shanqing , Huang Cheng 
Published: June 2023

AbstractMyasthenia gravis (MG) is an autoimmune disease (AD), and patients with MG often have other types of ADs. We analyzed the prognosis of patients with MG complicated by AD after thymectomy. A retrospective analysis was performed for patients with MG complicated by ADs treated surgically in our center over the past 22 years, and their general condition and follow-up data were collected and analyzed. 33 patients were included totally. 28 patients displayed improvement or even complete recovery of MG, and 23 of 36 ADs revealed improvement or even complete recovery. The prognosis of MG is significantly correlated with the duration of postoperative follow-up time (p = 0.028), and in patients with thymoma, the larger the tumor diameter, the better the prognosis of MG (p = 0.026). Thymic hyperplasia patients were predominantly female (p = 0.049) and young (p < 0.001). The most common concomitant AD in this study was a thyroid-associated AD, which was associated with thymic hyperplasia (p < 0.001), Osserman type I MG (p < 0.001), and young age (p < 0.001). Thymectomy had a good therapeutic effect on MG complicated by AD, and there was a close correlation between surgery, thymus, MG, and ADs.
The EU’s Proposed Reform of Directors’ Duties and the Missing Link to Soft Law
Authors: Ferrarini Guido , Siri Michele , Zhu Shanshan 
Published: June 2023

AbstractIn this paper, we investigate whether reform of EU company law is needed to make corporate governance more sustainable. We also consider some issues to which the EU proposals on company law and sustainability paid scant attention, such as the role of corporate governance codes and other types of soft law, mainly of international origin, in promoting sustainable governance. In addition, we underline that in recent years the EU has adopted several measures which offer better prospects for sustainable governance than the reform of directors’ duties the EU is currently debating. We conclude that the failure to take corporate governance codes and the existing regulatory framework into account could seriously impair pending reforms of directors’ duties and their link to sustainability.
Learning attribute and homophily measures through random walks
Authors: Antunes Nelson , Banerjee Sayan , Bhamidi Shankar , Pipiras Vladas 
Published: June 2023

AbstractWe investigate the statistical learning of nodal attribute functionals in homophily networks using random walks. Attributes can be discrete or continuous. A generalization of various existing canonical models, based on preferential attachment is studied (model class$$\mathscr {P}$$P), where new nodes form connections dependent on both their attribute values and popularity as measured by degree. An associated model class$$\mathscr {U}$$Uis described, which is amenable to theoretical analysis and gives access to asymptotics of a host of functionals of interest. Settings where asymptotics for model class$$\mathscr {U}$$Utransfer over to model class$$\mathscr {P}$$Pthrough the phenomenon of resolvability are analyzed. For the statistical learning, we consider several canonical attribute agnostic sampling schemes such as Metropolis-Hasting random walk, versions of node2vec (Grover and Leskovec, 2016) that incorporate both classical random walk and non-backtracking propensities and propose new variants which use attribute information in addition to topological information to explore the network. Estimators for learning the attribute distribution, degree distribution for an attribute type and homophily measures are proposed. The performance of such statistical learning framework is studied on both synthetic networks (model class$$\mathscr {P}$$P) and real world systems, and its dependence on the network topology, degree of homophily or absence thereof, (un)balanced attributes, is assessed.
A systematic review of the status of neuropsychological research and dementia in South Asia
Authors: Ahmed Tahera , Kumar Kuldeep , Zhang Ping 
Published: June 2023

AbstractIt is recognised that there is a notable presence of psychology and dementia-related issues in South Asian (SA) countries, and this problem is on the rise. Nevertheless, the problems found in the field of neuropsychology are yet to be fully resolved in the region. Unlike the case in developed countries, neuropsychology, despite the scopes and genuine potential, is not broadly practised in South Asia (which constitutes 25% of the world population), and the opportunity for extensive research is limited. Although India has made substantial progress in neuropsychology through the establishment of neuropsychological units and by developing assessment modules based on cultural requirements and the living standards of the population, the rest of the South Asia region is lagging far behind in the sphere of health science. Neuropsychology covers a vast area of brain-behaviour relationships, of which cognitive impairment is an important part. Except for India, other South Asian countries like Pakistan, Bangladesh, Sri Lanka, and Nepal have not had specific noteworthy studies on neuropsychology, but there have been a few research works done on neuropsychology, cognitive impairment, and other neurological assessments. This article focuses on reviewing the status of the development of neuropsychological research in South Asia, and it also assesses quantitative studies on dementia in the region where cognitive and neuropsychological assessments have been used.
Fausse route ! Avons-nous pris la mauvaise direction dans l’évaluation de nos conducteurs vieillissants au Québec ?
Authors: Lavallière Martin , Savoie Camille 
Published: June 2023

Au Québec, la Société de l’assurance automobile du Québec (SAAQ) est la seule instance responsable de la délivrance d’un permis ou de son retrait.* Récemment, la SAAQ annonçait qu’elle retirait l’obligation d’évaluation par un médecin ou un ophtalmologiste/optométriste pour les conducteurs âgés de 75 ans, repoussant cette première évaluation médicale obligatoire à 80 ans (SAAQ, 2021b). On invoque qu’une telle décision permettrait de délester le réseau de la santé d’une charge d’évaluation et de bureaucratie supplémentaire. De plus, il est invoqué que très peu de conducteurs se voyaient retirer leurs permis de conduire à la suite de ces évaluations à la SAAQ. Au cours des dernières années, moins de 2% des personnes âgées de 75 ans voyaient leur permis de conduire suspendu à la suite d’un examen médical ou visuel (SAAQ, 2021a). À cet effet, il est mentionné que la majorité des modifications apportées au droit de conduire portait sur le port de verres correcteurs ou la réduction des heures permises de conduite.
Older Mens’ Experiences with and Preferences for Physical Activity
Authors: Windt Sheralyn , Sims-Gould Joanie , Mackey Dawn C. , McKay Heather 
Published: June 2023

AbstractWe aim to describe older mens’ experiences with physical activity (PA) and their preferences for PA programs. We interviewed 14 men from a Canada-based PA intervention study called Men on the Move, and 5 men from a supplementary sample (who were not intervention participants). Content analysis was used to describe their experiences with PA and program preferences. The socio-ecological perspective and the hegemonic masculinity framework guided the research. PA barriers were low motivation, poor health, lack of time, interests other than PA and a lack of interest in PA, finances, lack of knowledge about PA, injury fear, social influences, inconvenience, weather, caregiving, built/natural environments, low-quality fitness instructors, and program structure. PA facilitators were chores, health, interest, time, motivation, social influences, active transportation, built/natural environments, good weather, program structure, and skilled/knowledgeable fitness instructors. PA program preferences were small group atmosphere, individualized attention/programming, equal number of men and women, sports programming, PA classes, and experienced instructors. Older men have distinct PA experiences. Promoting and designing programs that address their experiences may increase their PA.
The Case for Expanding Visual Assessments During Spaceflight
Authors: Waisberg Ethan , Ong Joshua , Masalkhi Mouayad , Zaman Nasif , Kamran Sharif Amit , Sarker Prithul , Tavakkoli Alireza , Lee Andrew G. 
Published: June 2023

AbstractSpaceflight associated neuro-ocular syndrome (SANS) is one of the potential barriers to human long-duration spaceflight (LDSF), including a manned mission to Mars. While a large barrier, the pathophysiology of SANS is not well understood, and functional and structural findings from SANS continue to be further characterized. Currently on the International Space Station (ISS), scheduled visual assessments are static visual acuity, Amsler grid, and a self-reported survey. Additional visual assessments may help the understanding of this neuro-ophthalmic phenomenon, as well as the effects of spaceflight of overall ocular health. In this paper, a case is made for expanding scheduled visual assessments to include dynamic visual, contrast sensitivity (CS), visual field testing, and virtual reality-based metamorphopsia assessment during spaceflight. These further assessments may play a key role in helping to determine the structural and functional changes associated with SANS, which are crucial to maintain astronaut vision during LDSF, as well as for developing countermeasures. Finally, a brief discussion is provided about current challenges to expanding visual testing during spaceflight and potential solutions to these barriers, specifically head-mounted visual assessment technology.
ANALYTICITY AND SYNTHETICITY IN TYPE THEORY REVISITED
Authors: BENTZEN BRUNO 
Published: June 2023

AbstractI discuss problems with Martin-Löf’s distinction between analytic and synthetic judgments in constructive type theory and propose a revision of his views. I maintain that a judgment is analytic when its correctness follows exclusively from the evaluation of the expressions occurring in it. I argue that Martin-Löf’s claim that all judgments of the forms
$a : A$
and
$a = b : A$
are analytic is unfounded. As I shall show, when A evaluates to a dependent function type
$(x : B) \to C$
, all judgments of these forms fail to be analytic and therefore end up as synthetic. Going beyond the scope of Martin-Löf’s original distinction, I also argue that all hypothetical judgments are synthetic and show how the analytic–synthetic distinction reworked here is capable of accommodating judgments of the forms
$A \> \mathsf {type}$
and
$A = B \> \mathsf {type}$
as well. Finally, I consider and reject an alternative account of analyticity as decidability and assess Martin-Löf’s position on the analytic grounding of synthetic judgments.
Shear Wave Velocities in the San Gabriel and San Bernardino Basins, California
Authors: Li Yida , Villa Valeria , Clayton Robert W. , Persaud Patricia 
Published: June 2023

AbstractWe construct a new shear velocity model for the San Gabriel, Chino and San Bernardino basins located in the northern Los Angeles area using ambient noise correlation between dense linear nodal arrays, broadband stations, and accelerometers. We observe Rayleigh and Love waves in the correlation of vertical (Z) and transverse (T) components, respectively. By combining Hilbert and Wavelet transforms, we obtain the separated fundamental and first higher mode of the Rayleigh wave dispersion curves based on their distinct particle motion polarization. Basin depths constrained by receiver functions, gravity, and borehole data are incorporated into the prior model. Our 3D shear wave velocity model covers the upper 3–5 km of the crust in the San Gabriel, Chino and San Bernardino basin area. The Vs model is in agreement with the geological and geophysical cross‐sections from other studies, but discrepancies exist between our model and a Southern California Earthquake Center community velocity model. Our shear wave velocity model shows good consistency with the CVMS 4.26 in the San Gabriel basin, but predicts a deeper and slower sedimentary basin in the San Bernardino and Chino basins than the community model.
Conjugative transfer of streptococcal prophages harboring antibiotic resistance and virulence genes
Authors: Huang Jinhu , Dai Xingyang , Wu Zuowei , Hu Xiao , Sun Junjie , Tang Yijun , Zhang Wanqiu , Han Peizhao , Zhao Jiaqi , Liu Guangjin , Wang Xiaoming , Mao Shengyong , Wang Yang , Call Douglas R , Liu Jinxin , Wang Liping 
Published: June 2023

Abstract
Prophages play important roles in the transduction of various functional traits, including virulence factors, but remain debatable in harboring and transmitting antimicrobial resistance genes (ARGs). Herein we characterize a prevalent family of prophages in Streptococcus, designated SMphages, which harbor twenty-five ARGs that collectively confer resistance to ten antimicrobial classes, including vanG-type vancomycin resistance locus and oxazolidinone resistance gene optrA. SMphages integrate into four chromosome attachment sites by utilizing three types of integration modules and undergo excision in response to phage induction. Moreover, we characterize four subtypes of Alp-related surface proteins within SMphages, the lethal effects of which are extensively validated in cell and animal models. SMphages transfer via high-frequency conjugation that is facilitated by integrative and conjugative elements from either donors or recipients. Our findings explain the widespread of SMphages and the rapid dissemination of ARGs observed in members of the Streptococcus genus.
Impact of bimetallic interface design on heat generation in plasmonic Au/Pd nanostructures studied by single-particle thermometry
Authors: Gargiulo Julian , Herran Matias , Violi Ianina L. , Sousa-Castillo Ana , Martinez Luciana P. , Ezendam Simone , Barella Mariano , Giesler Helene , Grzeschik Roland , Schlücker Sebastian , Maier Stefan A. , Stefani Fernando D. , Cortés Emiliano 
Published: June 2023

AbstractLocalized surface plasmons are lossy and generate heat. However, accurate measurement of the temperature of metallic nanoparticles under illumination remains an open challenge, creating difficulties in the interpretation of results across plasmonic applications. Particularly, there is a quest for understanding the role of temperature in plasmon-assisted catalysis. Bimetallic nanoparticles combining plasmonic with catalytic metals are raising increasing interest in artificial photosynthesis and the production of solar fuels. Here, we perform single-particle thermometry measurements to investigate the link between morphology and light-to-heat conversion of colloidal Au/Pd nanoparticles with two different configurations: core–shell and core-satellite. It is observed that the inclusion of Pd as a shell strongly reduces the photothermal response in comparison to the bare cores, while the inclusion of Pd as satellites keeps photothermal properties almost unaffected. These results contribute to a better understanding of energy conversion processes in plasmon-assisted catalysis.
Determinants of coping styles of people with Parkinson’s Disease
Authors: Prins Eva M. , Geerlings Angelika D. , Ben-Shlomo Yoav , Meinders Marjan J. , Bloem Bastiaan R. , Darweesh Sirwan K. L. 
Published: June 2023

AbstractLittle is known about how people with Parkinson’s disease (PD) cope with stressful life events. We examined the determinants of specific coping strategies and whether specific choices have any impact on quality of life (QoL). We recruited patients with PD who had been seen at a neurology outpatient clinic at least once during the past year as part of the PRIME-NL cohort study. Coping was measured using the Ways of Coping Questionnaire (WCQ) and QoL was measured using the Parkinson’s Disease Questionnaire (PDQ-39). 977 out of 988 participants completed the questionnaires and 935 participants were diagnosed with PD. Factor analysis was undertaken to test if ways of coping were similar or different to previous findings in a PD population. We used linear regression analyses to examine predictors of coping styles. We then used multivariable linear regression to test how coping style was associated with the domains of QoL conditional on potential confounders. The five coping styles identified by the factor analysis were: “taking action and emphasizing the positive”, “distancing and fantasizing”, “goal oriented and planful problem solving”, “seeking social support” and “avoidance and acceptance”. Age, gender, education and anxiety were associated with the type of coping strategy. For example, higher education was associated with more active coping strategies (e.g. β = 4.39,p < 0.001 for goal oriented). Conditional on other confounders, most coping strategies had little effect on QoL domains. These findings demonstrate that coping behavior of people with PD is influenced by psychological status and personal traits. However, there was only a modest effect of coping behavior on QoL. Future research needs to test whether the enhancement or discouragement of certain coping strategies is feasible and can enhance QoL.
Robotic monitoring of grasslands: a dataset from the EU Natura2000 habitat 6210* in the central Apennines (Italy)
Authors: Angelini Franco , Pollayil Mathew J. , Bonini Federica , Gigante Daniela , Garabini Manolo 
Published: June 2023

AbstractDespite the remarkable growth of the global market for robotics, robotic monitoring of habitats is still an understudied topic. This is true, among others, for the species-rich EU Annex I habitat “6210 - Semi-natural grasslands and scrubland facies on calcareous substrates”. This habitat is typically surveyed by human operators. In this work, we present a dataset concerning relevés performed through the quadrupedal robot ANYmal C. The dataset contains information from three plots, which include the robot state, videos, and images acquired to assess the habitat conservation status. Additionally, a collection of videos and pictures about two typical and one early warning species of habitat 6210 is also presented. This database is publicly available in the provided Zenodo repository and will aid researchers in several fields. Robot state information can be used by engineers to validate their algorithms, while data gathered by the robot can be used to design new methodologies and new metrics to assess the habitat conservation status or train/test classifiers (e.g. neural networks) for plant classification.
A large-scale fMRI dataset for human action recognition
Authors: Zhou Ming , Gong Zhengxin , Dai Yuxuan , Wen Yushan , Liu Youyi , Zhen Zonglei 
Published: June 2023

AbstractHuman action recognition is a critical capability for our survival, allowing us to interact easily with the environment and others in everyday life. Although the neural basis of action recognition has been widely studied using a few action categories from simple contexts as stimuli, how the human brain recognizes diverse human actions in real-world environments still needs to be explored. Here, we present the Human Action Dataset (HAD), a large-scale functional magnetic resonance imaging (fMRI) dataset for human action recognition. HAD contains fMRI responses to 21,600 video clips from 30 participants. The video clips encompass 180 human action categories and offer a comprehensive coverage of complex activities in daily life. We demonstrate that the data are reliable within and across participants and, notably, capture rich representation information of the observed human actions. This extensive dataset, with its vast number of action categories and exemplars, has the potential to deepen our understanding of human action recognition in natural environments.
Prognostication and risk factor stratification for survival of patients with hepatocellular carcinoma: a nationwide big data analysis
Authors: Choi Jin Woo , Kang Soohee , Lee Juhee , Choi Yunhee , Kim Hyo-Cheol , Chung Jin Wook 
Published: June 2023

AbstractThis study was conducted to identify risk factors affecting overall survival (OS) and provide prognostication for patients with hepatocellular carcinoma (HCC) using nationwide big data. Between January 2008 and December 2014, 10,573 adult patients with new HCC were registered in a nationwide database. Among them, 6830 patients without missing data were analyzed to construct a prognostication system. A validation cohort of 4580 patients was obtained from a tertiary hospital. All patients were assumed to have received the best treatment. A conditional inference tree analysis was performed to establish a prognostic system. The C-index and calibration plot for 5-year survival were estimated for validation. As a result, the tumor burden (TB) grade was the most significant factor in determining OS, and the cutoff was TB3 (TB1‒3 versus TB4). The patients were ultimately divided into 13 prognosis groups. The C-indexes were 0.714 and 0.737 (95% confidence interval, 0.733–0.742) in the nationwide (derivation) and hospital (validation) cohorts, respectively. In the calibration plot, the 5-year survival of the validation cohort largely matched the 45-degree line. In conclusion, the proposed prognostication system with a simple tree structure enabled the detailed stratification of patient prognosis and visualized the strata of risk factors affecting OS.
Prevalence and proportion estimate of asymptomatic Plasmodium infection in Asia: a systematic review and meta-analysis
Authors: Kotepui Manas , Kotepui Kwuntida Uthaisar , Masangkay Frederick Ramirez , Mahittikorn Aongart , Wilairatana Polrat 
Published: June 2023

AbstractAsymptomatic Plasmodium infection raises a problem for the persistent transmission of malaria in low-endemic areas such as Asia. This systematic review was undertaken to estimate the prevalence and proportion of asymptomatic Plasmodium infection in Asia. The systematic review was registered at PROSPERO (ID: CRD42022373664). The research followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. A comprehensive search of five databases, Ovid, Scopus, MEDLINE, PubMed, and Embase, was conducted to identify studies of asymptomatic Plasmodium infection in Asian countries. The pooled prevalence of asymptomatic Plasmodium infection, the pooled proportion of asymptomatic Plasmodium infection among all parasitised individuals, and the associated 95% confidence intervals were estimated using a random-effects model. A total of 916 articles were retrieved, and 87 articles that met the criteria were included in the systematic review. The pooled prevalence of asymptomatic Plasmodium infection among enrolled participants in Southeast Asia, South Asia, and Western Asia was 5.8%, 9.4%, and 8.4%, respectively. The pooled proportion of asymptomatic Plasmodium infection among all parasitised individuals in Southeast Asia, South Asia, and Western Asia was 89.3%, 87.2%, and 64.8%, respectively. There was a low prevalence of asymptomatic Plasmodium infection, but there was a high proportion of asymptomatic Plasmodium infection per all parasitised individuals in different parts of Asia. These results may support and facilitate elimination and control programs for asymptomatic Plasmodium infection in Asia.