bluuebunny/crossref_metadata_2025_split huggingface dataset:
Testing reciprocal associations between child anxiety and parenting across early interventions for inhibited preschoolers
Authors: Novick Danielle R. , Meyer Christian T. , Wagner Nicholas J. , Rubin Kenneth H. , Danko Christina M. , Dougherty Lea R. , Druskin Lindsay R. , Smith Kelly A. , Chronis‐Tuscano Andrea 
Published: August 2023

BackgroundGiven the robust evidence base for the efficacy of evidence‐based treatments targeting youth anxiety, researchers have advanced beyond efficacy outcome analysis to identify mechanisms of change and treatment directionality. Grounded in developmental transactional models, interventions for young children at risk for anxiety by virtue of behaviorally inhibited temperament often target parenting and child factors implicated in the early emergence and maintenance of anxiety. In particular, overcontrolling parenting moderates risk for anxiety among highly inhibited children, just as child inhibition has been shown to elicit overcontrolling parenting. Although longitudinal research has elucidated the temporal unfolding of factors that interact to place inhibited children at risk for anxiety, reciprocal transactions between these child and parent factors in the context of early interventions remain unknown.MethodThis study addresses these gaps by examining mechanisms of change and treatment directionality (i.e., parent‐to‐child vs. child‐to‐parent influences) within a randomized controlled trial comparing two interventions for inhibited preschoolers (N = 151): the multicomponent Turtle Program (‘Turtle’) and the parent‐only Cool Little Kids program (‘CLK’). Reciprocal relations between parent‐reported child anxiety, observed parenting, and parent‐reported accommodation of child anxiety were examined across four timepoints: pre‐, mid‐, and post‐treatment, and one‐year follow‐up (NCT02308826).ResultsHypotheses were tested via latent curve models with structured residuals (LCM‐SR) and latent change score (LCS) models. LCM‐SR results were consistent with the child‐to‐parent influences found in previous research on cognitive behavioral therapy (CBT) for older anxious youth, but only emerged in Turtle. LCS analyses revealed bidirectional effects of changes in parent accommodation and child anxiety during and after intervention, but only in Turtle.ConclusionOur findings coincide with developmental transactional models, suggesting that the development of child anxiety may result from child‐to‐parent influences rather than the reverse, and highlight the importance of targeting parent and child factors simultaneously in early interventions for young, inhibited children.
Comparative study of block cryoconcentration in pomegranate juice: Centrifugation versus vacuum
Authors: Vásquez‐Castillo Flor M. , Hernández Eduard , Ureña‐Peralta Milber O. , Achaerandio Isabel 
Published: August 2023

AbstractBlock cryoconcentration is a technique that can be applied to obtain fruit juice concentrates while preserving their nutritional, bioactive and organoleptic properties. Until now, the investigations present both the centrifugation and vacuum cryoconcentration method independently for different matrices, but with different purposes such as observing the effect of the initial freezing temperature, the freezing direction, whether radial or unidirectional, the effect of several cycles of cryoconcentration, comparing cryoconcentration with other concentration methods, etc. However, there is no study that compares both methods in the same matrix considering some common parameters such as cryoconcentration time. The objective of this research work was to compare two block centrifugation methods, centrifugation‐assisted (CABC) and vacuum‐assisted (VABC). A factorial experimental design was used. The operation conditions evaluated were 110 RCF and 2360 RCF, and 10 and 70 kPa at the same time conditions (4 and 12 min). Pomegranate juice was frozen at −20°C unidirectionally for 48 h before treatments. For the response studied—concentration index (CI), solute yield (SY, %) and efficiency (Eff, %)—CABC at 110 RCF for 12 min showed the best overall results (SY = 59.2% and Eff = 84.3%) and the desirability was .91. For VABC at 10 kPa for 12 min, the desirability was .98 but SY was lower. In both methods, the CI in one cycle was up to 3.0. The advantage of both systems is that in one cycle the CI, SY and Eff were higher than those obtained by other investigations on pomegranate juice.Practical applicationsCryoconcentration is an emerging technology for concentrating a food solute in a solution based on the separation of ice crystals from a freeze‐concentrated solution. The nutritional and sensory quality of cryoconcentrated fruit juices is higher than those concentrated conventionally by means of evaporation due to the low processing temperatures. Consumer demand for food rich in bioactive components for a healthy lifestyle is growing. With the use of the block freeze concentration technique, it is possible to produce a pomegranate juice concentrate with excellent nutritional properties. Two techniques for assisted block cryoconcentration of pomegranate juice—vacuum and centrifugal—were compared in a single cycle. Both methods showed better performance in once cycle than other cryoconcentration methods at lab scale. The generated knowledge in this study can be easily adapted for the juice industry in order to improve the process parameters of block freeze concentration in the elaboration of concentrated pomegranate juice.
Rising incidence and impact of early‐onset colorectal cancer in the Asia‐Pacific with higher mortality in females from Southeast Asia: a global burden analysis from 2010 to 2019
Authors: Danpanichkul Pojsakorn , Moolkaew Pinyada , Kanjanakot Yatawee , Polpichai Natchaya , Jaroenlapnopparat Aunchalee , Kim Donghee , Lukens Frank J. , Wassef Wahid , Fallon Michael B. , Chen Vincent L. , Lui Rashid , Wijarnpreecha Karn 
Published: August 2023

AbstractBackground and AimEarly‐onset colorectal cancer (CRC) is a growing global health concern, especially in the Asia‐Pacific region. However, comprehensive research on this topic from the region is lacking. Our study aims to investigate trends in early‐onset CRC in Asia over 10 years, filling this research gap.MethodsThis study utilized data from the Global Burden of Disease Study 2019 to assess temporal trends in early‐onset CRC in the Asia‐Pacific. The analysis included estimating annual frequencies and age‐standardized rates (ASRs) of early‐onset CRC incidence, death, and disability‐adjusted life‐years (DALYs) by gender.ResultsThe incidence of early‐onset CRC significantly increased in both regions with higher increase and in the Western Pacific region. Notable increases were observed among males in the Western Pacific and females in Southeast Asia (SEA). Mortality rates remained stable in the Western Pacific but increased by 10.6% in SEA, especially among females. DALYs due to CRC also increased significantly in SEA, with a greater rise among females. The Western Pacific had the highest CRC incidence, and in SEA, the mortality rate was higher in females than males.ConclusionsOur study reveals a substantial increase in early‐onset CRC in the Asia‐Pacific underscoring the urgency for effective interventions. Thus, a comprehensive approach comprising controlled risk reduction, health promotion to heightened disease awareness, and implementation of effective screening strategies should be executed timely to mitigate the burden of early‐onset CRC.
Pictures at an exhibition: How to share your imaging data
Authors: Hartley Matthew , Anita Liviu , Babalola Kolawole , Russell Craig , Yoldaş Aybüke Küpcü , Zulueta‐Coarasa Teresa 
Published: August 2023

AbstractOpen access to data underpinning published results is a key pillar of scientific reproducibility. Making data available at scale also provides opportunities for data reuse, encouraging the development of new analysis approaches. In this poster article, accompanying a recorded talk, we will explain the benefits of publicly archiving your image data alongside your published manuscripts, as well as highlight what resources are available to do this. This will include the BioImage Archive, EMBL‐EBI's new resource for biological image data, https://www.ebi.ac.uk/bioimage‐archive/. We will look at how image data submission works, how to prepare in advance for archiving your data and upcoming developments.
Parents' socioeconomic status and support to adult children across the life course
Authors: Kalmijn Matthijs 
Published: August 2023

AbstractObjectiveThis paper examines how parents' socioeconomic status (SES) affects the support parents give to children and how parents' SES moderates changes in support across children's life courses.BackgroundMany studies have documented effects of parents' SES on support to adult children, as well as effects of children's life course stages on received support, but few studies have examined how these two factors interact. A dynamic perspective on the social stratification of support can provide new clues about how parents transmit advantages across generations.MethodUsing prospective panel data on 10,822 parent–child dyads in the Netherlands from 2003 to 2015 and random and fixed effects models, this paper examines life course changes in the financial, practical, and informational support adult children (aged 18–59) receive from parents.ResultsPositive effects of parents' SES were found on informational and financial support, but there were no main effects on practical support. Informational support declined with age but later in higher‐SES families. Support declined after union formation and similarly for higher‐ and lower‐SES families. The increase in practical support when children became parents and single parents was stronger in higher‐SES families than in lower‐SES families. Stratification of financial support was stronger in early adulthood and increased again later in children's lives.ConclusionThere was evidence for a prolonged support pattern among higher‐SES families, combined with stronger effects of children's parenthood transitions in such families. Parents' SES affects support streams to adult children, but effects depend on the type of support and children's stage in the life course.
Effect of caseinate salt addition on the structural characteristics of kefiran systems
Authors: Exarhopoulos S. , Goulas A. , Dimitreli G. , Raphaelides Stylianos N. 
Published: August 2023

AbstractSodium caseinates–kefiran systems were studied to explore whether any potential interactions between them might exist. The study was performed using low‐deformation rheological techniques, which were dynamic and creep tests. The systems were prepared under various experimental conditions such as heating and acidification. Besides, the structure development of the systems in relation to time was also monitored using oscillatory shear rheometry. The results indicated that the structural characteristics of the systems were mainly affected by the state of the caseinates such as the formation of aggregates and to a lesser degree by the interactions of kefiran molecules with the caseinates. Freeze–thaw treatment produced cryogels with good thermal stability and fairly satisfactory mechanical properties. The morphology of the caseinate‐kefiran systems was also investigated by means of confocal laser scanning microscopy.
Influence of human development and predators on patterns of Virginia opossum occupancy, abundance, and activity
Authors: Veon J. T. , Lassiter E. V. , Johansson E. , Shaw M. , McTigue L. , Massey A. , Gibson R. , DeGregorio B. A. 
Published: August 2023

AbstractAs human development continues to expand, wildlife must relocate or adapt to survive. Many mammalian mesopredators, such as the Virginia opossum (Didelphis virginiana), have adapted to living alongside human development. Furthermore, top‐down predation pressure may be altered in nuanced ways within the human environment. Species such as opossums may be shielded from predation by human development or behavioral changes in predators. Understanding how dominant and subordinate mesopredators co‐exist across natural and developed areas will provide insight into how wildlife communities are structured. Our objective was to evaluate how opossum occupancy, abundance, and activity were associated with human development and the relative abundance of their predators. We used data from a nationwide camera trapping study, Snapshot USA, to estimate opossum occupancy, abundance, and activity. We related these measures to the surrounding landscape and urbanization variables. We found that opossum occupancy was positively associated with anthropogenic sound (a surrogate for human activity). Furthermore, opossums in heavily forested areas were more likely to be detected in locations with higher predicted anthropogenic sounds. In areas with a high density of human housing, opossum relative abundance increased when predator abundance increased. We also found opossums were strictly nocturnal and shifted their activity to earlier in the evening in the presence of high predator abundance. Our results suggest that humans and their urban development can have multidimensional impacts on opossum behavior and occurrence, and could facilitate changes in predator–prey dynamics. Future research should evaluate if the association of opossums with urban areas is due to human‐subsidized resources or caused by reduced mortality from altered predator–prey dynamics.
Integrative biological analyses of responses to food deprivation reveal resilience mechanisms in sea urchin larvae
Authors: Li Ning , Griffith Andrew W. , Manahan Donal T. 
Published: August 2023

AbstractA fundamental question in ecology is how organisms survive food deprivation. In the ocean, climate change is impacting the phenology of food availability for early life‐history stages of animals. In this study, we undertook an integrative analysis of larvae of the sea urchin Strongylocentrotus purpuratus—an important keystone species in marine ecology and a molecular biological model organism in developmental biology. Specifically, to identify the mechanisms of resilience that maintain physiological state and the ability of organisms to recover from food deprivation, a suite of molecular biological, biochemical, physiological and whole organism measurements was completed. Previous studies focused on the importance of energy reserves to sustain larvae during periods of food deprivation. We show, however, that utilization of endogenous energy reserves only supplied 15% of the metabolic requirements of long‐term survival (up to 22 days) in the absence of particulate food. This large energy gap was not supplied by larvae feeding on bacteria. Estimates of larval ability to transport dissolved organic matter directly from seawater showed that such substrates could fully supply metabolic needs. Integrative approaches allowed for filtering of gene expression signatures, linked with gene network analyses and measured biochemical and physiological traits, to identify biomarkers of resilience. We identified 14 biomarkers related to nutrition‐responsive gene expression, of which a specific putative amino acid transporter gene was quantified in a single larva experiencing continuous nutritional stress. Advances in applications of gene expression technologies offer novel approaches to determine the physiological state of marine larval forms in ecological settings undergoing environmental change.
A novel role of the fission yeast sulfiredoxin Srx1 in heme acquisition
Authors: Vahsen Tobias , Brault Ariane , Mourer Thierry , Labbé Simon 
Published: August 2023

AbstractThe transporter Str3 promotes heme import in Schizosaccharomyces pombe cells that lack the heme receptor Shu1 and are deficient in heme biosynthesis. Under microaerobic conditions, the peroxiredoxin Tpx1 acts as a heme scavenger within the Str3‐dependent pathway. Here, we show that Srx1, a sulfiredoxin known to interact with Tpx1, is essential for optimal growth in the presence of hemin. The expression of Srx1 is induced in response to low iron and repressed under iron repletion. Coimmunoprecipitation and bimolecular fluorescence complementation experiments show that Srx1 interacts with Str3. Although the interaction between Srx1 and Str3 is weakened, it is still observed in tpx1Δ mutant cells or when Str3 is coexpressed with a mutant form of Srx1 (mutD) that cannot bind Tpx1. Further analysis by absorbance spectroscopy and hemin‐agarose pull‐down assays confirms the binding of Srx1 to hemin, with an equilibrium constant value of 2.56 μM. To validate the Srx1‐hemin association, we utilize a Srx1 mutant (mutH) that fails to interact with hemin. Notably, when Srx1 binds to hemin, it partially shields hemin from degradation caused by hydrogen peroxide. Collectively, these findings elucidate an additional function of the sulfiredoxin Srx1, beyond its conventional role in oxidative stress defense.
Tissue‐specific stilbene accumulation is an early response to wounding/grafting as revealed by using spatial and temporal metabolomics
Authors: Loupit Grégoire , Fonayet Josep V. , Lorensen Marcus D. B. B. , Franc Céline , De Revel Gilles , Janfelt Christian , Cookson Sarah J. 
Published: August 2023

AbstractGrafting is widely used in horticulture. Shortly after grafting, callus tissues appear at the graft interface and the vascular tissues of the scion and rootstock connect. The graft interface contains a complex mix of tissues, we hypothesised that each tissue has its own metabolic response to wounding/grafting and accumulates different metabolites at different rates. We made intact and wounded cuttings and grafts of grapevine, and then measured changes in bulk flavonoid, phenolic acid and stilbenoid concentration and used metabolite imaging to study tissue‐specific responses. We show that some metabolites rapidly accumulate in specific tissues after grafting, for example, stilbene monomers accumulate in necrotic tissues surrounding mature xylem vessels. Whereas other metabolites, such as complex stilbenes, accumulate in the same tissues at later stages. We also observe that other metabolites accumulate in the newly formed callus tissue and identify genotype‐specific responses. In addition, exogenous resveratrol application did not modify grafting success rate, potentially suggesting that the accumulation of resveratrol at the graft interface is not linked to graft union formation. The increasing concentration of complex stilbenes often occurs in response to plant stresses (via unknown mechanisms), and potentially increases antioxidant activity and antifungal capacities.
The relationship between health and housing in low‐income older adults: A secondary analysis of survey data
Authors: Kantz Mary E. , Enah Comfort , Abdallah Lisa M. 
Published: August 2023

AbstractObjectiveTo examine the health‐housing relationship in low‐income older adults, and differences by income and receipt of housing assistance.DesignSecondary analysis of longitudinal survey data.SampleAbout 10,858 adults aged 62+ who completed at least one wave of the 2014 Survey of Income and Program Participation (SIPP) (n = 37,333 observations).MeasurementsSIPP variables representing demographics and housing quality, affordability, stability, and neighborhood were analyzed. Low‐income and higher‐income participants were differentiated by the household income‐to‐poverty ratio.ResultsLow‐income participants were significantly more likely to be in poor health and report problems with housing quality, affordability, and neighborhood safety compared to higher‐income participants (p < .001). Increased household size and problems with housing quality and neighborhood safety were associated with poor health in both groups (p < .05). Low‐income participants who received housing assistance were significantly poorer, less healthy, and food insecure than participants not receiving assistance (p < .001); however, the health‐housing relationship was not different in the two groups.ConclusionsResults provide additional support for housing as a social determinant of older adult health. Though housing assistance programs reached a subset of low‐income older adults, the results suggest a housing assistance shortfall. Implications for public health nurses and researchers are explored.
Does acclimation in distinct light conditions determine differences in the photosynthetic heat tolerance of coffee plants?
Authors: Vilas‐Boas T. , Duarte A. A. , Della Torre F. , Lovato M. B. , Lemos‐Filho J. P. 
Published: August 2023

Abstract
Worldwide coffee production is threatened by climate change, which highlights the importance of heat tolerance studies. Here we tested the hypothesis that photosynthetic heat tolerance in coffee varieties changes according to acclimation to distinct light conditions. Furthermore, we tested if heat tolerance is associated with the habitat of origin of the coffee species.
We evaluated heat tolerance using chlorophyll fluorescence in varieties of Coffea arabica (Mundo Novo and Catuai Amarelo) and C. canephora (Conilon) grown in a common garden under two conditions: high (HS) and low (LS) sunlight. Leaf traits associated with leaf cooling were evaluated in plants grown in LS and HS and associations of heat tolerance with these traits were determined.
The varieties tested had high photosynthetic heat tolerance, with temperatures above 54 °C leading to a 50% reduction in Fv/Fm (T50). The heat tolerance of each Coffea variety was unaffected by growth in distinct light conditions. Leaves of plants grown in LS were larger and had a lower fraction of the leaf area occupied by stomata (nast). Heat tolerance was positively associated with leaf size and negatively with nast. C. canephora exhibited higher heat tolerance than C. arabica.
The limited plasticity of heat tolerance in response to acclimation under distinct light conditions contradicts the prediction that plants acclimated to HS would have higher photosynthetic heat tolerance than those acclimated to LS. Our results on heat tolerance among Coffea species/varieties in HS and LS indicate the possibility of selection of varieties for better acclimation to ongoing climate changes.