bluuebunny/crossref_metadata_2025_split huggingface dataset:
Infecção pelo Hpv na região Sul do Brasil: uma revisão integrativa da literatura
Authors: Ataides Monique Cezimbra , Calil Luciane Noal , Mezzomo Lisiane Cervieri 
Published: January 2023

O papilomavírus humano (HPV) infecta pele e mucosas e causa, na grande maioria dos casos, lesões transitórias que podem evoluir para câncer. O objetivo deste estudo é avaliar, por meio de revisão integrativa, a literatura disponível sobre a frequência da infecção pelo HPV na região Sul do Brasil. Buscou-se nas bases de dados PubMed, Literatura Latino-americana e do Caribe em Ciências da Saúde (Lilacs) e Scientific Electronic Library Online (SciELO) a frequência de HPV na região Sul do Brasil nos últimos dez anos. Foram identificados oito estudos que se enquadraram nos critérios da pesquisa. A prevalência estimada de infecção pelo HPV foi de 46,19%. Os genótipos mais encontrados foram HPV 6, de baixo risco, e os subtipos HPV 16, HPV 18, HPV 31 e HPV 58, de alto risco. Nas amostras classificadas como LSIL/HSIL ou de células escamosas atípicas (ASC), tipos virais de baixo risco HPV 6, HPV 11 e HPV 44 foram os mais prevalentes, enquanto para os de alto risco os subtipos HPV 16, HPV 18 e HPV 58 foram os mais encontrados. Embora tenham sido identificados poucos estudos com essa temática nos últimos anos, a partir dos dados da pesquisa foi possível estimar a prevalência do HPV no Sul do Brasil e seus genótipos mais frequentes. Essa informação é importante para o planejamento das ações de saúde pública e dos serviços de saúde, contribuindo para a elaboração de estratégias de controle e prevenção da infecção.
A Guide for Selection of Genetic Instruments in Mendelian randomisation (MR) studies of Type-2 diabetes and HbA1c: towards an integrated approach
Authors: Garfield Victoria , Salzmann Antoine , Burgess Stephen , Chaturvedi Nish 
Published: January 2023

<p>This study examines the instrument selection strategies currently employed throughout the type-2 diabetes and HbA1c MR literature. We then argue for a more integrated and thorough approach, providing a framework to do this in the context of HbA1c and diabetes. We conducted a literature search for Mendelian randomisation studies that have instrumented diabetes and/or HbA1c. We also used data from the UK Biobank (N=349,326) to calculate instrument strength metrics that are key in MR studies (the F-statistic for average strength and R2 for total strength) with two different methods (‘Individual-level data regression’ and Cragg-Donald formula). We used a 157-SNP instrument for diabetes and a 51-SNP instrument (as well as partitioned into glycaemic and erythrocytic) for HbA1c. Our literature search yielded 48 studies for diabetes and 22 for HbA1c. Our UKB empirical examples showed that irrespective of, the method used to calculate metrics of strength and whether the instrument was the main one or was partitioned by function, the HbA1c genetic instrument is strong in terms of both average and total strength. For diabetes, a 157-SNP instrument was shown to have good average and total strength, but these were both substantially smaller than those of the HbA1c instrument. We provide a careful set of five recommendations to researchers who wish to genetically instrument type-2 diabetes and/or HbA1c. MR studies of glycaemia should take a more integrated approach when selecting genetic instruments and we give specific guidance on how to do this. </p>
FGF4L2 retrogene copy number is associated with intervertebral disc calcification and vertebral geometry in Nova Scotia Duck Tolling Retrievers
Authors: Bianchi Catarina A. , Marcellin-Little Denis J. , Dickinson Peter J. , Garcia Tanya C. , Li Chai-Fei , Batcher Kevin , Bannasch Danika L. 
Published: January 2023

Abstract

OBJECTIVES
To evaluate the effects of the chondrodystrophy-associated FGF4L2 retrogene on intervertebral disc (IVD) calcification and vertebral geometry.

ANIMALS
22 Nova Scotia Duck Tolling Retrievers (NSDTR) with no FGF4L2 retrogene (n = 7, wild-type dogs), 1 retrogene copy (8, heterozygous dogs), or 2 retrogene copies (7, homozygous dogs).

PROCEDURES
Computed tomography (CT) scans of the vertebral column were analyzed using computer-aided design (CAD) software. IVD calcification, vertebral column length, and vertebral geometry of the third cervical (C3), 13th thoracic (T13), and first lumbar (L1) vertebrae were compared.

RESULTS
IVD calcification was not found in wild-type dogs. IVD calcification was more frequent in homozygous dogs than heterozygous (P = .008) or wild-type dogs (P < .001) and in heterozygous dogs compared to wild-type dogs (P < .001). Four IVDs were subclinically herniated in 3 dogs (2 homozygous, 1 heterozygous). Calcified IVD had a greater volume and surface area in heterozygous dogs than homozygous dogs. C3 vertebral canal height-to-width ratio was greater in homozygous dogs than heterozygous dogs (P = .044) and wild-type dogs (P = .010).

CLINICAL RELEVANCE
IVD calcification and vertebral geometry can be analyzed using CAD software. The presence of 1 or 2 FGF4L2 copies in the absence of the FGF4L1 retrogene has an additive effect on the number of calcified IVD and a minor effect on vertebral geometry in NSDTR dogs. Data support the use of FGF4L2 phenotyping to reduce clinical disease in segregating breeds and to monitor the introduction of wild-type alleles into fixed breed populations.
GPR Application for Non-Rigid Road Pavement Condition Assessment
Authors: Batrakov Dmitry O. , Antyufeyeva Mariya S. , Batrakova Angelika G. 
Published: January 2023

Abstract
The main aim of the article is to demonstrate the effectiveness of the use of ground penetrating radars to assess various objects using the example of assessing the current state of highways. The article uses the software developed by the authors and the corresponding mathematical models. The analysis of the results obtained is based on mathematical models that have proven their effectiveness and is time-tested. It should be emphasised that the main problem in assessing roads with non-rigid pavement is associated with a change in the main parameters of the layers – thickness and dielectric constant. Previously, we proposed a scheme for the layer-by-layer determination of the values of the relative permittivity and then - the subsequent determination of the thickness of each layer, starting from the top layer and ending with the base. The paper presents the results of experiments actually carried out by the authors with various GPRs, which not only have different values of the central frequency, but also have significant design differences. In addition, the results of processing real data using the software developed by the authors are presented. As a result, an improved method of signal calibration has been proposed, which makes it possible to increase the reliability of assessing the thickness of road surfaces, as well as other objects.
A State of the Art in Simultaneous Localization and Mapping (SLAM) for Unmanned Ariel Vehicle (UAV): A Review
Authors: Rauf Abdul , Irshad Muhammad Jehanzeb , Wasif Muhammad , Mehmood Zubair , Kiren Tayybah , Siddique Nazam 
Published: January 2023

AbstractFor the past decade, the main problem that has attracted researchers’ attention in aerial robotics is the position estimation or Simultaneous Localization and Mapping (SLAM) of Unmanned Aerial Vehicles (UAVs) where the GPS signal is poor or denied. This article reviews the strengths and weaknesses of existing methods in the field of aerial robotics. There are many different techniques and algorithms that are used to overcome the localization and mapping problem of these UAVs. These techniques and algorithms use different sensors, such as Red Green Blue-Depth (RGB_D), Light Detecting and Ranging (LIDAR), and Ultra-wideband (UWB). The most common technique is used, i.e., probability-based SLAM, which uses two algorithms: Linear Kalman Filter (LKF) and Extended Kalman Filter (EKF). LKF consists of five phases and this algorithm is just used for linear system problems. However, the EKF algorithm is used for non-linear systems. Aerial robots are used to perform many tasks, such as rescue, transportation, search, control, monitoring, and different military operations because of their vast top view. These properties are increasing their demand as compared to human service. In this paper, different techniques for the localization of aerial vehicles are discussed in terms of advantages and disadvantages, practicality and efficiency. This paper enables future researchers to find the suitable SLAM solution based on their problems; either the researcher is dealing with a linear problem or a non-linear problem.
Does Fiscal Transparency Matter for Bank Development? A Lookup on Emerging and Developing Countries
Authors: Trabelsi Emna 
Published: January 2023

Abstract
This paper examines how fiscal transparency is linked to bank development. It also hypothesizes that the effect is mediated by reasonable channel(s). Drawing upon a panel dataset of emerging and developing economies, we find that fiscal transparency is positively related to the private credit and to the ratio of liquid assets, implying that more transparent policies enhance bank development. Our panel regressions and the mediation analysis also suggest that the effect of fiscal transparency on private credit is significantly transmitted through the control of corruption, while it has a direct effect on the ratio of liquid assets.
Revisiting of Interest Rate Channel: Nonlinear transmission of Monetary Policy Shocks to the Turkish Economy
Authors: Yildirim Durmus Cagri , Turan Tugba 
Published: January 2023

Abstract
This study examines the effectiveness of non-linear monetary policy interest rate channel shocks for the Turkish economy using the threshold VAR analysis in the period of 2006-2019. The interest channel is examined with the two models for both consumption transfer and investment transfer models. The results show that the interest rate channel is effective in the high regime (high macroeconomic instability) for the consumption transfer model, and it is partially effective in the low regime (low macroeconomic instability). On the other hand, for the model with investment expenditures flow, the interest rate channel is partially effective in both high and low regimes.
Testing the Factors that Determine the Profitability of Banks with a Dynamic Approach: Evidence from Turkey
Authors: Doğan Mesut , Yildiz Feyyaz 
Published: January 2023

Abstract
The present study aims to identify the internal and external factors that affect the profitability of banks operating in Turkey. For this purpose, the study used data from 23 public, private, and foreign banks, covering the period from 2007 to 2020. Two dependent variables were used as the profitability indicators of banks, namely, the Return on Equity (ROE) and the Return on Assets (ROA). In order to increase the reliability of the models developed during the study, Dynamic Generalized Method of Moments (GMM) and Fixed Effect Model (FEM) were applied. Results of the analysis indicate a positive and statistically significant relation between inflation rate and GDP growth rate, and ROA and ROE. According to the results of GMM, there was a positive relation between ROA and ROE, and 1-year and 2-year lagged ROA and ROE. This situation may be explained by the fact that profits acquired in the Turkish banking sector are steady. ROA and ROE were observed to have a positive relation with inflation rate and economic growth rate. In other words, the increase in inflation rate and GDP growth rate positively affect profitability of public, private, and foreign banks.
Effects of dynamic contrast enhancement on transition zone prostate cancer in Prostate Imaging Reporting and Data System Version 2.1
Authors: Zhang Jiahui , Xu Lili , Zhang Gumuyang , Zhang Xiaoxiao , Bai Xin , Sun Hao , Jin Zhengyu 
Published: January 2023

Abstract

Background
The aim of the study was to analyse the effects of dynamic contrast enhanced (DCE)-MRI on transitional-zone prostate cancer (tzPCa) and clinically significant transitional-zone prostate cancer (cs-tzPCa) in Prostate Imaging Reporting and Data System (PI-RADS) Version 2.1.

Patients and methods
The diagnostic efficiencies of T2-weighted imaging (T2WI) + diffusion-weighted imaging (DWI), T2WI + dynamic contrast-enhancement (DCE), and T2WI + DWI + DCE in tzPCa and cs-tzPCa were compared using the score of ≥ 4 as the positive threshold and prostate biopsy as the reference standard.

Results
A total of 425 prostate cases were included in the study: 203 cases in the tzPCa group, and 146 in the cs-tzPCa group. The three sequence combinations had the similar areas under the curves in diagnosing tzPCa and cs-tzPCa (all P < 0.05). The sensitivity of T2WI + DCE and T2WI + DWI + DCE (84.7% and 85.7% for tzPCa; 88.4% and 89.7% for cs-tzPCa, respectively) in diagnosing tzPCa and cs-tzPCa was significantly greater than that of T2WI + DWI (79.3% for tzPCa; 82.9% for cs-tzPCa). The specificity of T2WI + DWI (86.5% for tzPCa; 74.9% for cs-tzPCa) were significantly greater than those of T2WI + DCE and T2WI + DWI + DCE (68.0% and 68.5% for tzPCa; 59.1% and 59.5% for cs-tzPCa, respectively) (all P > 0.05). The diagnostic efficacies of T2WI + DCE and T2WI + DWI + DCE had no significant differences (all P < 0.05).

Conclusions
DCE can improve the sensitivity of diagnosis for tzPCa and cs-tzPCa, and it is useful for small PCa lesion diagnosis.
AKIBAT HUKUM DAN KEKABURAN NORMA DALAM PENGATURAN UNDANG-UNDANG TENTANG TANGGUNG JAWAB SOSIAL PERSEROAN TERBATAS
Authors: Harjono Dhaniswara K. 
Published: January 2023

Limited Liability Companies in Indonesia, under the applicable law (Law 40/2007 and PP 47/2021), are under the obligation to realize its corporate social responsibility. The idea of CSR is to force the company to make it presence felt beneficially by the local community and wider society. Unfortunately, not all companies are willing and able to meet its corporate social responsibility, or even if they chose to do so, proportionality is disregard. This paper, using Rudolph von Jhering's point of view, explores and identifies what legal or non-legal factors hinders the implementation of CSR.
أهل الذمة في مصر في عهد السلطان الناصر محمد بن قلاوون
Authors: Bakheet Faiz Ali 
Published: January 2023

إن المتتبع لأحوال أهل الذمة في إطار الدولة العربية الإسلامية يجد انه عاشوا بسلام وأمان لفترات طويلة ، على الرغم من وجود بعض المضايقات التي تحصل في عهد سلطان ,لذا أصبح أهل الذمة من النسيج الاجتماعي المصري بدءً من الفتوحات الإسلامية في عهد الخلافة الراشدة والدولة الأموية والعباسية امتداداً إلى عهد الدولة المملوكية وخاصة ما يخص حقبة البحث في عهد السلطان محمد بن قلاوون الذي كان من أكثر سلاطين المماليك عطفاً وتسامحاً تجاه أهل الذمة ,والدليل على ذلك انه أمر بإعادة من طرد منهم إلى وظيفته فضلا عن منع الأذى عنهم , فلذلك تمتعوا في عهده بالأمان والطمأنينة , اللهم إذا استثنينا بعض الحوادث العارضة التي كانت تؤدي إلى تغير في سياسة السلطان تجاهم , إلا أن ذلك الأمر كان يزول بزوال الدافع من وراءه.
ANALISIS AGROINDUSRI DAN STRATEGI PENGEMBANGAN GULA AREN DI DESA RAMBAH TENGAH HULU KECAMATAN RAMBAH KABUPATEN ROKAN HULU PROVINSI RIAU
Authors: M.Charizal Purba  , Fahrial  
Published: January 2023

Palm sugar agro industry can providr an add value to palm sugar producers and overcome labor challenges If the business is managed properly, the purpose of this study is to analysis: the characteristics and profiles of palm sugar producers, palm sugar processing techniques, palm sugar production cost, production, revenue, efficiency, and value added, and make palm sugar marketing strategy. This study used a survey method. The research site was in Rambah Tengah Hulu Village, Rambah District, Rokan Hulu Regency, Riau Province. In this study, 15 producers were selected by snowball sampling. The collected data consisted of primary and secondary data. The method of data analysis used descriptive qualitative analysis and quantitative descriptive. The results showed that the characteristics of palm sugar producers had an average age of 50 years, male gender, 6 years of education level, 10 years of business experience, and the family number of 5 persons. The palm sugar agroindustry was home industry business, private business capital, and labor are come from the family. The process of palm sugar in the research area used simple technology. The cost spent by the producers were Rp. 122,742, revenue Rp. 149,400, profits Rp. 26,658 with an R / C ratio 1.21. The added value obtained from processing palm sugar per process was Rp. 131,400 with a value-added ratio of 87.95%, and a margin value of Rp. 147,400, direct labor income was 0.67%, other input contributions were 10.85%, and profits were 88.46%. Based on the SWOT matrix analysis, it showed that the business was in quadrant I or SO strategy (strengths and opportunities). This strategy shows that the situation is very favorable for entrepreneurs by utilizing their strengths to take advantage of business opportunities.
Prefrontal association of subthalamic deep brain stimulation with rapid eye movement sleep behavior disorder in Parkinson’s disease
Authors: Xue Tao , Fan Houyou , Chen Shujun , Guo Zijian , Wang Huizhi , Han Chunlei , Yang Anchao , Meng Fangang , Bai Yutong , Zhang Jianguo 
Published: January 2023

OBJECTIVE
Subthalamic nucleus (STN)–deep brain stimulation (DBS) in Parkinson’s disease (PD) patients affects not just focused target areas but also diffuse brain networks. The effect of this network modulation on nonmotor DBS effects is not fully understood. By concentrating on the sleep domain, the authors comprehensively determined the influence of electrode location and related structural/functional connections on changes in probable rapid eye movement (REM) sleep behavior disorder (pRBD) symptoms after STN-DBS, which has been reported to ameliorate, deteriorate, or remain constant.

METHODS
Preoperative and postoperative pRBD symptoms were documented in 60 PD patients. The volumes of tissue activated (VTAs) were assessed on the basis of individual electrode reconstructions and merged with normative connectome data to identify structural/functional connections associated with VTAs. The entire cohort was used to construct connection models that explained changes in pRBD symptoms, as well as to perform cross-validations.

RESULTS
Structural/functional connectivity was associated with pRBD symptom changes during STN-DBS. Changes in pRBD symptoms were predicted using an ideal structural connection map. Prefrontal connection was related with improved pRBD symptoms, whereas sensorimotor connectivity was associated with deterioration.

CONCLUSIONS
Recovery of pRBD symptoms was predicted on the basis of the fibers connecting the STN electrode to prefrontal regions. These findings implied that the placement of STN-DBS leads influences the fibers to prefrontal regions and may be used to enhance treatment of pRBD symptoms; however, further prospective studies are needed to validate these findings.
Epidemiology, Evaluation and Surgical Treatment of undescended Testis in North Macedonia in the Period from 2011 to 2020.
Authors: Memeti Shaban , Todorovic Lazar , Kamiloski Marjan , Risteski Toni , Coklevska Shuntov Natalia , Lumani Bakiji Njomza , Gjorikj Sanja 
Published: January 2023

Background; Cryptorchidism or undescended testis (UDT) is one of the most common pediatric disorders of the male endocrine glands and the most common genital disorder identified at birth. The main reasons for treatment of cryptorchidism include increased risks of impairment of fertility potential, testicular malignancy, testis torsion, and/or associated inguinal hernia
Material and Methods; The aim of this study is to show the epidemical distribution of this pathology in the republic of North Macedonia from 2011-2020 and simultaneously show the number of cases in every city of Macedonia. The number of cases (by city) is shown in Table 1.
All data is provided by the archives of The Institute of Public Health, North Macedonia.
Discussion: It is very important to find if there is a correlation between the number of undescended testis cases in North Macedonia to the environment, genetics, level of education, level of health care institutions, etc.
Reduced hormonal levels, reduced fertility and increased risk of testicular cancer are the most common side effects of no treatment or late treatment.
Conclusion; This condition of the undescended testis is very common, and the possible effects of late treatment or no treatment at all are very risky. So, we have to pay attention to the risks in order to try to provide better treatment at the right point of age.
KEANEKARAGAMAN SERANGGA HAMA PADA TANAMAN PADI DENGAN APLIKASI Streptomyces sp. DAN Trichoderma sp. DI DESA MOJOTENGAH KABUPATEN GRESIK
Authors: Wiranthi Alifta , Suryaminarsih Penta , Windriyanti Wiwin 
Published: January 2023

Tanaman padi seringkali mendapat gangguan dari organisme pengganggu tumbuhan (OPT) yang mengakibatkan menurunnya kualitas serta kuantitas produksi padi. upaya meningkatkan produksi bahan, agar mendapatkan hasil produksi dengan kualitas dan kuatitas yang tinggi adalah dengan pengendalian hama terpadu (PHT). Permasalahan hama dan penyakit tanaman merupakan bagian yang tidak dapat lepas dalam budidaya tanaman. Pemanfaatan agensi hayati sangat efektif dari segi biaya dan mengurangi efek negatif yan ditimbulkan oleh penggunaan pestisida kimia. Mikroorganisme merupakan agensi hayati yang mampu mengendalikan serangga hama. Genus Steptomyces sp. dan Trichoderma sp. menghaslkan enzim kitinase. Penelitian ini bertujuan mengetahui pengaruh aplikasi agensi hayati Streptomyces sp. dan Trichoderma sp. terhadap jenis, komposisi, dan populasi serangga, indeks keanekaragaman hama pada lahan tanaman padi di Desa Mojotengah Kabupaten Gresik. Penelitian ini menggunakan metode survei menggunakan cara pengamatan langsung, penangkapan serangga dilakukan menggunakan jaring (sweep net), perangkap likat kuning (yellow sticky trap), dan perangkap sumuran (pitfall trap). hasil penelitian dilahan pertanaman padi dengan populasi serangga yang ditemukan pada lahan dengan aplikasi agensi hayati sejumlah 280 individu dan tanpa agensi hayati 775 individu. Aplikasi agensi hayati Streptomyces sp. dan Trichoderma sp. berpengaruh terhadap jumlah populasi hama. Aplikasi agensi hayati Streptomyces sp. dan Trichoderma sp. berpengaruh terhadap nilai indeks keanekaragaman jenis termasuk kategori sedang, indeks kemerataan pada kedua lahan termasuk kategori sedang, indeks kekayaan jenis menunjukkan tingkat kekayaan jenis tinggi pada kedua lahan, indeks dominasi menunjukan nilai termasuk kategori sedang.