bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efficiency and quality improvement in pathology diagnostic by using computational pathology: software-based analysis of perineural invasion in colon carcinoma
Authors: Demirdag Dora , Khacheishvili Mariam , Baidoshvili Alexi 
Published: August 2023

Abstract
Introduction:
Many pathology laboratories are transitioning from diagnostics with glass slides to diagnostics with whole-slide images (WSI). One of the advantages of digital pathology is the possibility of using the software. Annotations made by software could increase the efficiency and the quality of pathologists´ work. In this research, annotations for nerves were used in WSI´s of colon carcinoma cases to help the detection of perineural invasion to improve the efficiency (time needed to find perineural invasion) and quality (the possibility of finding more perineural invasion in colon carcinoma cases and standardization) of the diagnostics.
Materials & Methods
4 pathologists got 148 colon carcinoma cases without annotations made by software to screen the slides for perineural invasion. After a minimum of 4 weeks of washing out, they got the same instances with annotations for nerves made by software to find perineural invasion. We compared the time they needed for the cases with and without annotations and the percentage of perineural invasion found with and without annotations.
Results
All 4 pathologists took advantage of the annotations made by software regarding the time they needed to conclude the perineural invasion, and the difference between the average time of all 4 pathologists without and with the use of software was statistically significant. All 4 pathologists found individual more perineural invasion. However, the average % of found perineural invasion without and with the help of software needed to be more substantial.
Neuropathological Findings in COVID-19 vs non-COVID-19 Acute Respiratory Distress Syndrome - A Case-Control Study
Authors: Humayun Mariyam , Zhang Lucy , Zaikos Thomas D. , Kannapadi Nivedha , Suarez Jose I. , Hager David N. , Troncoso Juan C. , Cho Sung-min 
Published: August 2023

Abstract
Objective:
Acute brain injury (ABI) and neuroinflammation is reported in COVID-19 and acute respiratory distress syndrome (ARDS). It remains unclear if COVID-19 plays an independent role in development of ABI compared to those with non-COVID-19 ARDS. We aimed to evaluate if COVID-19 ARDS is associated with higher risk and specific patterns of ABI compared to non-COVID-19 ARDS.
Design
Age and sex matched case-control autopsy study
Setting
A tertiary academic center
Subjects
Adult patients with COVID-19 and non-COVID-19 ARDS who died during hospitalization and underwent autopsy.
Measurements and Main Results
10 patients with COVID-19 ARDS were matched to 20 non-COVID-19 ARDS patients. Baseline demographics were comparable between the two groups including severity of ARDS (p=0.3). The frequency of overall ABI (70% vs 60%), infratentorial ABI (40% vs 25%), ischemic infarct (40% vs 25%), intracranial hemorrhage (30% vs 35%) and hypoxic-ischemic brain injury (30% vs 35%) was similar between COVID-19 and non-COVID-19 ARDS patients, respectively (p>0.05). Intracapillary megakaryocytes were exclusively seen in 30% of COVID-19 patients.
Conclusions:
Overall, frequency and pattern of ABI in COVID-19 ARDS was comparable to non-COVID-19.
Bayesian Networks for Risk Assessment and Postoperative Deficit Prediction in Intraoperative Neurophysiology for Brain Surgery
Authors: Pescador Ana Mirallave , Lavrador José Pedro , Lejarde Arjel , Bleil Cristina , Vergani Francesco , Baamonde Alba Díaz , Soumpasis Christos , Bhangoo Ranjeev , Kailaya-Vasan Ahilan , Tolias Christos M. , Ashkan Keyoumars , Zebian Bassel , Requena Jesus 
Published: August 2023

Abstract

Purpose
To this day there is no consensus regarding evidence of usefulness of Intraoperative Neurophysiological Monitoring (IONM). Randomized controlled trials have not been performed in the past mainly because of difficulties in recruitment control subjects. In this study, we propose the use of Bayesian Networks to assess evidence in IONM.
Methods
Single center retrospective study from January 2020 to January 2022. Patients admitted for cranial neurosurgery with intraoperative neuromonitoring were enrolled. We built a Bayesian network with utility calculation using expert domain knowledge based on logistic regression as potential causal inference between events in surgery that could lead to central nervous system injury and postoperative neurological function.
Results
A total of 267 patients were included in the study: 198 (73.9%) underwent neuro-oncology surgery and 69 (26.1%) neurovascular surgery. 50.7% of patients were female while 49.3% were male. Using the Bayesian Network´s original state probabilities, we found that among patients who presented with a reversible signal change that was acted upon, 59% of patients would wake up with no new neurological deficits, 33% with a transitory deficit and 8% with a permanent deficit. If the signal change was permanent, in 16% of the patients the deficit would be transitory and in 51% it would be permanent. 33% of patients would wake up with no new postoperative deficit. Our network also shows that utility increases when corrective actions are taken to revert a signal change.
Conclusions
Bayesian Networks are an effective way to audit clinical practice within IONM. We have found that IONM warnings can serve to prevent neurological deficits in patients, especially when corrective surgical action is taken to attempt to revert signals changes back to baseline properties. We show that Bayesian Networks could be used as a tool to calculate the utility of conducting IONM, which could save costs in healthcare when performed.
Fertility Desire and Associated Factors among Reproductive Age Women Attending Antiretroviral Therapy at Public Hospitals in Eastern Ethiopia
Authors: Abera Legesse , Mengistu Betelhem 
Published: August 2023

Abstract

Background
Human Immune Virus remained the major cause of death in children and women of reproductive age worldwide. The desire of a human immune deficiency virus-infected person to have children in the future has significant implications for the transmission of the human immune deficiency virus to sexual partner and new born. However, fertility desire has been given little attention and the uptake of PMTCT services is limited in the study area. Therefore, this study aimed to assess fertility desire and associated factors among reproductive age women living with Human Immune Virus attending antiretroviral therapy in public hospitals Eastern Ethiopia.
Methods
A facility-based cross-sectional study was conducted November 01–30/2022 among 598 reproductive age women attending antiretroviral therapy clinic in public hospitals in Eastern Ethiopia. A systematic random sampling technique was used to select participants. Data were collected by five female nurses through face-to-face interview using a structured and pretested questionnaire. Data were entered into Epi-Data 3.1 and analyzed by SPSS Version 24. Bivariate and multivariable logistic regression analyses were conducted. Variables with P value < 0.25 in bivariate analysis were taken into multivariable logistic regression analysis and variables associated with fertility desire were declared at P-value < 0.05 with Adjusted Odds Ratio and 95% CIs.
Results
This study showed that, 42.0% (95% CI: 31.7% -52.28%) of women have fertility desire. Women age (15–24) (AOR = 2.52: 95% CI: 1.58–3.50), married women (AOR = 3.21, 95% CI 1.42–5.11), having no children (AOR = 1.94: 95% CI: 1.51–2.52), partner desire to have children (AOR = 2.98: 95% CI: 1.84–4.12) were significantly associated with fertility desire.
Conclusion
This study revealed that significant proportion of women having fertility desire in the study area in spite of their positive status. Moreover, being young age, married, having no child, and partners desire to have children were factors associated with fertility desire. Therefore, service providers should strongly focus on counseling and provision of full information about the possible risks of mother to child transmission of Human Immune Virus and how to prevent it, with more attention to young and married women, women having no child, and women who their partners desire to have more children.
Cancer survivorship programs and care delivery models for cancer survivors’ transition in South Korea: A scoping review
Authors: Jin Dal-Lae , Choi Won Jung , Hur Ryun , Seo Hyun-Ju , Yoon Seok-Jun 
Published: August 2023

Abstract
Purpose
This scoping review aimed to identify unmet healthcare needs in cancer survivors after cancer treatment and provide an overview of evidence on their transitional care in Korea.
Methods
Studies reporting supportive care interventions, care delivery models, survival experience post-treatment, and factors affecting the health status of Korean cancer survivors were searched in Ovid MEDLINE, CINAHL, OvidEmbase, Cochrane CENTRAL, KoreaMed, and RISS in January 2021. Extracted data were subjected to descriptive analysis of the contextual data and quantitative analysis using appropriate descriptive statistics (review protocol registration number: osf.io/4mfzu/).
Results
Twenty-nine articles were included. Two models of after-care delivery were identified: the shared care model and the adapted chronic care model. Six studies confirmed that cancer survivors needed social support and stress interventions after treatment to address their multiple physical, social, and emotional difficulties as they progressed through the survival stages. Additionally, nine studies reported that cancer survivors identified unmet needs and needed supportive care, physical therapy, and psychosocial therapy.
Conclusion
This review explored available evidence and knowledge gaps in research to provide insights into Korean cancer survivorship care. The findings suggest that efforts to enhance the cancer survivorship care approach, such as a comprehensive care plan and ongoing delivery of survivorship care led by health professionals, are required to address cancer survivors’ unmet care needs during transitional care post-treatment in Korea.
Designing a Contactless, AI System to Measure the Human Body using a Single Camera for the Clothing and Fashion Industry
Authors: Montazerian Mohammad , Leymarie Frederic Fol 
Published: August 2023

Abstract
We present a system that estimates upper human body measurements using a set of computer vision and machine learning techniques. In a nutshell, the main steps involve: (1) using a portable camera (such as from a smartphone); (2) improving the image quality; (3) isolating the human body from the surrounding environment; (4) performing a calibration step; (5) extracting features of the body from the image; (6) indicating markers on the image; (7) producing refined final results.
Using a single RGB camera to obtain accurate body dimensions rather than measuring these manually or via more complex multi-camera or more expensive laser-based sensors, has a high application potential for the apparel (fashion) industry.
We also present in this paper, ellipse-like approximations with the aim of minimizing the difference between the results of direct (hand) and software measurements. The human body circumferences can be well approximately represented by varying elliptic cross sections, and these can be adapted to each individual. We show that better results than the current state-of-the-art are obtained based on a simple criterion. In our study, we selected a set of two equations, out of many other possible choices, to best estimate upper human body horizontal cross sections.
We experimented with the system on a diverse sample of participants. The results for the upper human body measurements in comparison to the traditional manual method of tape measurements, when used as a reference, show ±1cm average differences, which is sufficient for a number of applications.
Movement and facial perception
Authors: Morrison Edward R. , O’Donnell Zak , Gregory Nicola J. 
Published: August 2023

Abstract

Movement is a neglected component of many studies of facial perception, yet biological movement can influence social perceptions by conveying information about identity, sex, and disposition. We aimed to quantify the importance of facial movement in perceptions of attractiveness, trustworthiness, and dominance, by isolating static and dynamic cues using facial motion-tracking. 42 speed-daters were filmed talking with an opposite-sex partner during a speed-dating interaction. Motion-tracking was used to isolate the movement information and create point-light faces, which were rated along with the original videos and facial photographs, by 73 independent raters. Regression models showed that static cues were generally important predictors of overall perceptions, albeit less so for perceptions of trustworthiness. Dynamic cues only contributed to perceptions of male trustworthiness and female dominance. Movement can be a significant component some perceptions, perhaps because it indicates personality and behavioural disposition. Judgements of attractiveness might be more linked to biological quality which is indicated by static cues such as shape and colour, rather than dynamic cues.
Transfacet full-endoscopic posterior lumbar interbody fusion for lumbar degenerative diseases: Consecutive case series
Authors: Shen Xu , Gao Yu-cheng , Zhang Pei , Xuan Wen-bin , Song Peng , Gao Zeng-xin 
Published: August 2023

Abstract
Objective
To introduce the operative technique for a transfacet full-endoscopic posterior lumbar interbody fusion (Endo-PLIF) and evaluate the clinical effect.
Methods
41 patients were treated with single-segment Endo-PLIF from July 2020 to July 2021. General demographic and perioperative data were recorded. VAS and ODI scores were evaluated at 1, 6,12 months postoperatively and the last follow-up. The radiological outcomes were based on the disk height (DH) at 3 months after operation.
Results
All cases were successfully completed surgery and followed for at least one year. The mean estimated blood loss was 81.53 ± 25.96 ml, operative time was 210.24 ± 37.06 minutes and postoperative hospitalization days were 4.71 ± 1.42 days, the VAS and ODI scores at each time point after surgery were significantly decreased in comparison with the preoperative scores(p < 0.05). The DH was significantly heightened postoperatively compared to the preoperative images(p < 0.05).
Conclusion
Transfacet Endo-PLIF is a minimally invasive, safe, and satisfactory surgery for lumbar degenerative diseases (LDD).
Transmitted costly signaling theory (TCS): an evolutionary perspective of inequality transmission at Liangzhu culture sites, southern coastal China
Authors: Liu Ruizhe , Zou Guannan 
Published: August 2023

Abstract
Extensive studies in multiple disciplines have discussed how materials and spatial access can serve as status indicators in human societies. Scholars interested in social inequality and its mechanisms have particularly drawn attention to how inequality is transmitted between two generations. This study presents a new framework, transmitted costly signaling (TCS), which synthesizes costly signaling theory (CST) and cultural evolution theory (CET) to explore inequality transmission in human societies. Using multi-methodologies, we investigate the Neolithic Liangzhu sites in China to test two hypotheses. Firstly, we examine if jade materials and burial space served as indicators of social status. Secondly, we explore if burial practices could be learned and transmitted by the lower class, indicating inequality transmission over time. Our findings reveal that the Liangzhu people used jade and larger burial sizes as costly signals to demonstrate social status, subsequently transmitting this burial practice as an indirect cultural feature. And the early Liangzhu period exhibited relative equality, followed by a middle period characterized by social hierarchy, and eventually, a decline in hierarchical society during the late Liangzhu. This research highlights the compatibility of TCS with biased transmission of cultural traits, particularly when social status is chosen as the demonstrator trait. By analyzing materials, spatial access, and social status, we gain valuable insights into the complexities of inequality transmission across generations in prehistorical societies.
Pt/C catalysts containing CeO2 with different morphologies for the hydrogen evolution reaction
Authors: Qi Pengran , You Jia , Wang Yi , Tian Liangliang , Qi Tao 
Published: August 2023

Abstract
Pt/C catalysts containing four different morphologies of CeO2 as co-catalysts were synthesized in this work, and their electrocatalytic performance for hydrogen evolution reaction (HER) was investigated. As compared with the Pt/C catalyst, these four catalysts containing CeO2 all exhibited improved catalytic activity. Among them, the Pt/C catalyst containing spherical CeO2 with a diameter of 30 ~ 60 nm (Pt/C-CeO2(s2)) possesses the best catalytic activity, displaying an over-potential of 258 mV at 10 mA cm− 2 and a Tafel slope of 42 mV dec− 1. According to the characterization results of structure, morphology and elemental valence state, the enhancement of catalytic activity is ascribed to the small particle size and good dispersion degree of Pt, as well as the strong interaction between the exposed (111) crystal plane of small spherical CeO2 and Pt, which leads to a significant increase in metallic Pt content. Moreover, the Pt/C-CeO2(s2) catalyst also demonstrates outstanding long-term stability besides exceptional catalytic activity. The results clearly illustrate that CeO2 with diverse shapes and sizes can remarkably influence the catalytic performance of loaded Pt particles in the HER process.
LicochalconeB Inhibits cGAS-STING Signaling Pathway and Prevents Autoimmunity Diseases
Authors: luo wei , Xu Guang , Wang Hongbo , zheng Song , Chen Yuanyuan , Mu Wenqing , Wen Jincai , Zhang Ping , Xiao Xiaohe , Bai Zhaofang 
Published: August 2023

Abstract
Cytosolic DNA activates the STING (stimulator of interferon genes) signaling pathway to trigger interferon and inflammatory responses that protect against microbial infections and cancer. However, Aicardi–Goutières syndrome (AGS) persistently activates the STING signaling pathway, which can lead to severe autoimmune diseases. We demonstrate herein that Licochalcone B (LicoB), the main component of traditional licorice, is an inhibitor of the STING signaling pathway. We observed that LicoB inhibited the activation of the STING signaling pathway in macrophages. Mechanically, LicoB affected the STING-TBK1-IRF3 signal axis and inhibited the activation of the STING downstream signaling pathway. Furthermore, LicoB inhibited the increase in type I interferon levels in mice induced by the STING agonist CMA. LicoB significantly reduced systemic inflammation in Trex1−/− mice. Our results show that LicoB, a STING signaling pathway inhibitor, is a promising candidate for the treatment of diseases related to STING signaling pathway activation.
The Relationship between Leadership, Organizational and Market Characteristics and Services Provided among IHS Urban Indian Health Programs
Authors: Tribble Grant , Borkowski Nancy , Corso Phaedra , Hall Allyson , Hearld Kristine R. 
Published: August 2023

Abstract
The Urban Indian Health Program (UIHP) was created by the Indian Health Service to establish a culturally appropriate health care delivery model for Native Americans who relocate into urban areas. For each of the 31 UIHP facilities, the geography, socioeconomic characteristics, and culture of the patient mix is varied, and the leaders of each facility affect the strategic direction and planning of the health care services offered and the adaptation of the health care services offerings to each of its populations. The purpose of this exploratory study was to determine if, within the UIHP, there is a relationship among the characteristics of the leaders and the leader’s strategic decisions relating to services provided. We found that the planning and execution of the UIHP’s strategy depends upon a variety of factors including the leaders’ individual characteristics, the organizational characteristics of each program, and the market factors of each service area.
Secure AI Model Sharing: A Cryptographic Approach for Encrypted Model Exchange
Authors: Neyigapula Bheema Shanker 
Published: August 2023

Abstract
The secure exchange of cryptographic keys is crucial for ensuring the confiden- tiality and integrity of AI models during sharing and collaboration. This research paper focuses on proposing a secure key exchange approach specifically tailored for encrypted model sharing. By addressing the key distribution problem inherent in AI model sharing, this approach establishes a secure and robust mechanism for exchanging cryptographic keys. The paper provides an overview of secure key exchange techniques, including public key cryptography, Diffie-Hellman key exchange, and elliptic curve cryptography, and discusses their application in the context of AI model sharing. The implementation details and evaluation results demonstrate the effectiveness and security of the proposed secure key exchange approach, offering a reliable solution for ensuring the confidentiality and integrity of shared AI models.
Experiences from a 10-week weight-neutral treatment program for patients with clinical binge eating disorder and higher weight
Authors: Berg Kjersti Hognes , Eik-Nes Trine Tetlie , Natvik Eli 
Published: August 2023

Abstract
Background
Weight based stigma might drive the development of both higher weight and binge eating disorder (BED). To improve treatment and outcomes, a deeper understanding of how stigma and shame are related in health-care practices is needed. The current study was designed to gain insight into how participating in a 10-week weight neutral treatment program for patients with binge eating disorder and higher weight was experienced.
Methods
Semi structured interviews were conducted with 10 patients who had completed the BED-treatment. The intervention was group based, emphasizing stigma and shame, using models of attachment and affect regulation in the presentation of BED. Interviews were analyzed guided by van Manen’s hermeneutic-phenomenological approach.
Results
A profound feeling of inferiority due to higher weight appeared to have kept the participants stuck in a behavioral cycle of dieting, weight loss, bingeing and weight regain. In addition, participants, and health care professional’s mutual acknowledgement of driving elements of binge eating in treatment, and less focus on behavioral change related to weight and eating, appeared to stimulate a feeling of equality. Feeling equal was described by participants as facilitating increased awareness and tolerance of bodily sensations and emotions, and a deeper understanding and self-caring attitude towards themselves. Feeling less shame was described as important for self-disclosure in family relationships, leading to increased understanding and support from others. Simultaneously, our findings indicate that uncertainty related to coping with food, eating and weight in unchanged, stigmatizing surroundings was profound after end of treatment.
Conclusions
The results indicate that relational dynamics of inferiority and equality may maintain and reverse BED-symptoms respectively. Health-care professionals engaging in a more equal distribution of power trough recognition, compassionate acceptance, and mutual investigation of subjective experience might contribute to reducing stigma and shame and the burdensome notion of inferiority among people with higher weight suffering from binge eating disorder.
Trial registration
The study was approved and registered by the Data Access Committee at Nord-Trøndelag Hospital Trust August 8th, 2019, registration number 2019_2335.