bluuebunny/crossref_metadata_2025_split huggingface dataset:
Patient characteristics, outcomes and hospital-level healthcare costs of foreign body ingestion from an Australian, non-prison referral centre
Authors: Ngu Natalie Lee Yee , Karp Jadon , Taylor Kirstin 
Published: February 2023

ObjectiveForeign body ingestion (FBI) occurs infrequently but can be associated with rare risks including perforation. There is limited understanding of the impact of adult FBI in Australia. We aim to evaluate patient characteristics, outcomes and hospital costs of FBI.DesignA retrospective cohort study of patients with FBI was performed at a non-prison referral centre in Melbourne, Australia. International Classification of Disease-10 coding identified patients with gastrointestinal FBI over financial years 2018–2021. Exclusion criteria were food bolus, medication foreign body, object in anus or rectum, or non-ingestion. Criteria for ‘emergent’ classification were oesophagus, size >6 cm, disc batteries, airway compromise, peritonitis, sepsis and/or suspected viscus perforation.ResultsThirty-two admissions attributed to 26 patients were included. The median age was 36 years (IQR: 27–56), 58% were male and 35% had a prior psychiatric or autism spectrum disorder. There were no deaths, perforations or surgery. Gastroscopy was performed in 16 admissions and 1 was scheduled following discharge. Rat-tooth forceps were used in 31% and an overtube was used in 3 cases. The median time from presentation to gastroscopy was 673 minutes (IQR: 380–1013). Management was adherent to European Society of Gastrointestinal Endoscopy guidelines in 81%. After excluding admissions with FBI as a secondary diagnosis, median admission cost was $A1989 (IQR: $A643–$A4976) and total admission costs over the 3 years was $A84 448.ConclusionFBI in an Australian, non-prison referral centre is infrequent, can often be safely managed expectantly, and has limited impact on healthcare utilisation. Early, outpatient endoscopy could be considered for non-urgent cases, which may reduce costs while maintaining safety.
Clicks away from reduced healthcare expenditures: leveraging the electronic health record to reinforce education efforts
Authors: Jensen Chelsee Jo , Honsey Theresa , Thielen Michaela K , Spitale Mari S , Marlette Bethany J , Kennedy Erika , Olson Rachel L , O’Laughlin Danielle J 
Published: February 2023

ObjectivesLupron 11.25 mg has both a narrow indication and a high cost compared to other Lupron presentations. Prior to our study initiation there was no clear distinction between presentations when ordering within the health-system’s Electronic Health Record (EHR). This resulted in inappropriate product selection, payment and billing errors that negatively impact our healthcare system. To reinforce prior education efforts, a new approach was considered leveraging the EHR with information to steer prescribers to the proper Lupron presentation based on indication. This study aimed to reduce off-label prescribing for Lupron 11.25 mg (NDC 00074-3663-03) by 25% by 02/28/2022 without negatively impacting the insurance collection rate.MethodsBaseline Lupron 11.25 mg adult kit administrations one year prior to intervention and off-label prescribing was found to account for 22.7% of administrations. In December 2021 intervention order questions were added to Lupron 11.25 mg in the EHR. One and two-month data was obtained after implementing order questions within the EHR. Lupron 11.25 mg administrations were classified into one of four categories to determine impact on off-label prescribing.ResultsIn the one- and two-month post-implementation periods off-label prescribing was 0% and 15.3% respectively, a reduction of 22.7% to and 7.4% respectively from the baseline assessment. There were no clinical denials found in either post-implementation reporting period.ConclusionThis report adds to the body of evidence that leveraging the EHR can lead to healthcare savings and illustrates how patient and healthcare system burden can be reduced by prompting thought and direction when a medication has indication specific dose requirements.
Antepartum and labour-related single predictors of non-participation, dropout and lost to follow up in a randomised controlled trial comparing internet-based cognitive–behaviour therapy with treatment as usual for women with negative birth experiences and/or post-traumatic stress following childbirth
Authors: Sjömark Josefin , Svanberg Agneta , Viirman Frida , Larsson Margareta , Poromaa Inger , Skalkidou Alkistis , Jonsson Maria , Parling Thomas 
Published: February 2023

ObjectivesInternet-based interventions are often hampered by high dropout rates. The number of individuals who decline to participate or dropout are reported, but reasons for dropout are not. Identification of barriers to participation and predictors of dropout may help improve the efficacy of internet-based clinical trials. The aim was to investigate a large number of possible predictors for non-participation and dropout in a randomised controlled trial for women with a negative birth experience and/or post-traumatic stress following childbirth.SettingA childbirth clinic at a university hospital in Sweden.ParticipantsThe sample included 1523 women who gave birth between September 2013 and February 2018. All women who rated an overall negative birth experience on a Likert scale, and/or had an immediate caesarean section (CS), and/or severe postpartum haemorrhage (≥ 2000 mL) were eligible.MethodsDemographic, antepartum, and labour-related/postpartum predictors were investigated for non-participation (eligible but denied participation), pre-treatment dropout (prior to intervention start), treatment dropout, and loss to follow-up. Descriptive statistics and logistic regression were used in the data analysis.ResultsA majority (80.3 %) were non-participants. Non-participation was predicted by lower level of education, being foreign-born, no experience of counselling for fear of childbirth, multiparity, vaginal delivery (vs CS and vacuum-assisted delivery) and absence of: preeclampsia, anal sphincter injury and intrapartum fetal distress. Pretreatment dropout was predicted by the absence of severe haemorrhage. Treatment dropout was predicted by vaginal delivery (vs immediate CS), vertex presentation and good overall birth experience. Loss to follow-up was predicted by vaginal delivery (vs immediate CS or vacuum-assisted delivery) and absence of intrapartum fetal distress.ConclusionsMothers with no obstetric complications were more likely to not participate and dropout at different time points. Both demographic, antepartum and obstetrical variables are important to attend to while designing procedures to maximise participation in internet-delivered cognitive–behavioral therapy.Trial registration numberISRCTN39318241
Outcome measures for children with speech sound disorder: an umbrella review protocol
Authors: Harding Sam , Burr Sam , Cleland Joanne , Stringer Helen , Wren Yvonne 
Published: February 2023

IntroductionSpeech sound disorder (SSD) describes a ‘persistent difficulty with speech sound production that interferes with speech intelligibility or prevents verbal communication’. There is a need to establish which care pathways are most effective and efficient for children with SSD. Comparison of care pathways requires clearly defined, evidence-based interventions and agreement on how to measure the outcomes. At present, no list of assessments, interventions or outcomes exists.The objective of this paper is to provide a rigorous and detailed protocol for an umbrella review of assessments, interventions and outcomes that target SSD in children. The protocol details the development of a search strategy and trial of an extraction tool.Methods and analysesThe umbrella review has been registered with PROSPERO (CRD42022316284). Papers included can use a review methodology of any sort but must include children of any age, with an SSD of unknown origin. In accordance with the Joanna Briggs Institute scoping review methods guidelines, an initial search of the Ovid Emcare and Ovid Medline databases was conducted. Following this, a final search strategy for these databases were produced. A draft extraction form was developed.Ethics and disseminationEthical approval is not needed for an umbrella review protocol. Following the systematic development of an initial search strategy and extraction form, an umbrella review of this topic can take place. Dissemination of findings will be through peer-reviewed publications, social media, and patient and public engagement.
Mechanical thrombectomy for the treatment of primary and secondary distal medium-vessel occlusion stroke: systematic review and meta-analysis
Authors: Rodriguez-Calienes Aaron , Vivanco-Suarez Juan , Sequeiros Joel M , Galecio-Castillo Milagros , Zevallos Cynthia B , Farooqui Mudassir , Ortega-Gutierrez Santiago 
Published: February 2023

BackgroundThere is limited evidence on the indication and role of mechanical thrombectomy (MT) in patients with distal medium-vessel occlusions (DMVOs). The aim of this systematic review and meta-analysis was to evaluate all the evidence available on the efficacy and safety of MT techniques (stent retriever, aspiration) in primary and secondary DMVOs.MethodsFive databases were searched from inception to January 2023 for studies of MT in primary and secondary DMVOs. Outcomes of interest included favorable functional outcome (90-day modified Rankin scale (mRS) 0–2), successful reperfusion (modified Thrombolysis in Cerebral Infarction (mTICI) 2b-3), symptomatic intracerebral hemorrhage (sICH), and 90-day mortality. Prespecified subgroup meta-analyses according to the specific MT technique and to the vascular territory (distal M2-M5, A2-A5, P2-P5) were also performed.ResultsA total of 29 studies with 1262 patients were included. For primary DMVOs (n=971 patients), pooled rates of successful reperfusion, favorable outcome, 90-day mortality and sICH were 84% (95% confidence interval (CI) 76 to 90%), 64% (95% CI 54 to 72%), 12% (95% CI 8 to 18%), and 6% (95% CI 4 to 10%), respectively. For secondary DMVOs (n=291 patients), pooled rates of successful reperfusion, favorable outcome, 90-day mortality and sICH were 82% (95% CI 73 to 88%), 54% (95% CI 39 to 69%), 11% (95% CI 5 to 20%), and 3% (95% CI 1 to 9%), respectively. Subgroup analyses by MT technique and by vascular territory showed no differences in primary and secondary DMVOs.ConclusionOur findings suggest that MT using aspiration or stent retriever techniques appears to be effective and safe in primary and secondary DMVOs. However, given the level of evidence of our results, further confirmation in well-designed randomized controlled trials is needed.
Production of tensor glueball in ultraperipheral pp, AuAu and PbPb collisions
Authors: Kou Wei , Chen Xurong 
Published: February 2023

AbstractIn this work, we discuss the production of a tensor glueball in the proton–proton and nuclei–nuclei ultraperipheral collisions (UPCs). The cross section is calculated in the equivalent photon approximation (EPA). The total UPCs cross section is related to the matrix elements of $$\gamma \gamma \rightarrow \pi ^0 G_2$$

γ
γ
→

π
0

G
2

process, which can be described in terms of the neutral pion and tensor glueball $$G_2$$

G
2

’s distribution amplitudes. The predictions for the rapidity distributions of UPCs cross sections and total cross sections are presented. The theoretical uncertainty of the whole calculation is considered. We consider the decay modes of the final-state tensor glueball and estimate the corresponding number of events. We estimate that there are about 10 tensor glueball $$G_2\rightarrow \phi \phi $$

G
2

→
ϕ
ϕ

signal events in PbPb collisions at the LHC. We also argue that the lead–lead UPC experiments at future HE-LHC and FCC experiments will provide larger opportunities to measure tensor glueballs.
Reinterpreting deformed Heisenberg algebras
Authors: Wagner Fabian 
Published: February 2023

AbstractMinimal and maximal uncertainties of position measurements are widely considered possible hallmarks of low-energy quantum as well as classical gravity. While General Relativity describes interactions in terms of spatial curvature, its quantum analogue may also extend to the realm of curved momentum space as suggested, e.g. in the context of Relative Locality in Deformed Special Relativity. Drawing on earlier work, we show in an entirely Born reciprocal, i.e. position and momentum space covariant, way that the quadratic Generalized Extended Uncertainty principle can alternatively be described in terms of quantum dynamics on a general curved cotangent manifold. In the case of the Extended Uncertainty Principle the curvature tensor in position space is proportional to the noncommutativity of the momenta, while an analogous relation applies to the curvature tensor in momentum space and the noncommutativity of the coordinates for the Generalized Uncertainty Principle. In the process of deriving this map, the covariance of the approach constrains the admissible models to an interesting subclass of noncommutative geometries which has not been studied before. Furthermore, we reverse the approach to derive general anisotropically deformed uncertainty relations from general background geometries. As an example, this formalism is applied to (anti)-de Sitter spacetime.
The ELBE infrared and THz facility at Helmholtz-Zentrum Dresden-Rossendorf
Authors: Helm M. , Winnerl S. , Pashkin A. , Klopf J. M. , Deinert J.-C. , Kovalev S. , Evtushenko P. , Lehnert U. , Xiang R. , Arnold A. , Wagner A. , Schmidt S. M. , Schramm U. , Cowan T. , Michel P. 
Published: February 2023

Abstract
The coherent infrared and THz sources driven by the superconducting electron accelerator ELBE are described. The present status of the facility is summarized and a few scientific highlights are mentioned. Finally plans for a successor facility (Dresden Advanced Light Infrastructure, DALI) are outlined along with the most important scientific and technological challenges.

Graphical abstract
Further results on (total) restrained Italian domination
Authors: Ridha Abdulhasan A. M. , Mojdeh D. A. 
Published: February 2023

An Italian dominating function on a graph [Formula: see text] is defined as a function [Formula: see text] satisfying the condition that every vertex [Formula: see text] for which [Formula: see text] is adjacent to at least one vertex [Formula: see text] for which [Formula: see text] or at least two vertices [Formula: see text] for which [Formula: see text]. The weight of an Italian dominating function is [Formula: see text]. The Italian domination number is the minimum weight taken over all Italian dominating functions of [Formula: see text] and denoted by [Formula: see text]. Three domination parameters related to the Italian dominating function are total Italian, restrained Italian, and total restrained Italian dominating function. A total ((restrained) (total restrained)) Italian dominating function [Formula: see text] is an Italian dominating function if the set of vertices with positive label ((the set of vertices with label [Formula: see text]), (at the same time, the set of vertices with positive label and the set of vertices with label [Formula: see text])) induces ((induces) (induce)) a subgraph with no isolated vertex. A minimum weight of any total ((restrained) (total restrained)) Italian dominating function [Formula: see text] is called a total ((restrained) (total restrained)) Italian domination number denoted by [Formula: see text], (([Formula: see text]) ([Formula: see text])). We initiate the study of parameters, restrained and total restrained Italian domination number of a graph [Formula: see text] and the middle graph of [Formula: see text]. For the family of standard graphs, we obtain the exact value of these parameters. For arbitrary graph [Formula: see text], we obtain the sharp bounds of these parameters, and for some corona graphs, we establish the precise value of these parameters.
Performance Analysis of Work Stealing Strategies in Large-Scale Multithreaded Computing
Authors: Kielanski Grzegorz , Van Houdt Benny 
Published: February 2023

Distributed systems use randomized work stealing to improve performance and resource utilization. In most prior analytical studies of randomized work stealing, jobs are considered to be sequential and are executed as a whole on a single server. In this article, we consider a homogeneous system of servers where parent jobs spawn child jobs that can feasibly be executed in parallel. When an idle server probes a busy server in an attempt to steal work, it may either steal a parent job or multiple child jobs.
To approximate the performance of this system, we introduce a Quasi-Birth-Death Markov chain and express the performance measures of interest via its unique steady state. We perform simulation experiments that suggest that the approximation error tends to zero as the number of servers in the system becomes large. To further support this observation, we introduce a mean field model and show that its unique fixed point corresponds to the steady state of the Quasi-Birth-Death Markov chain. Using numerical experiments, we compare the performance of various simple stealing strategies as well as optimized strategies.
Characteristics, Mortality, and Clinical Outcomes of Hospitalized Patients with COVID-19 and Diabetes: A Reference Single-Center Cohort Study from Poland
Authors: Kania Michał , Mazur Konrad , Terlecki Michał , Matejko Bartłomiej , Hohendorff Jerzy , Chaykivska Zlata , Fiema Mateusz , Kopka Marianna , Kostrzycka Małgorzata , Wilk Magdalena , Klupa Tomasz , Witek Przemysław , Katra Barbara , Klocek Marek , Rajzer Marek , Malecki Maciej T. 
Published: February 2023

Background. Diabetes is a risk factor for a severe course of COVID-19. We evaluated the characteristics and risk factors associated with undesirable outcomes in diabetic patients (DPs) hospitalized due to COVID-19. Materials and Methods. The data analysis of patients admitted between March 6, 2020, and May 31, 2021, to the University Hospital in Krakow (Poland), a reference center for COVID-19, was performed. The data were gathered from their medical records. Results. A total number of 5191 patients were included, of which 2348 (45.2%) were women. The patients were at the median age of 64 (IQR: 51–74) years, and 1364 (26.3%) were DPs. DPs, compared to nondiabetics, were older (median age: 70 years, IQR: 62–77 vs. 62, IQR: 47–72, and

p

< 0.001) and had a similar gender distribution. The DP group had a higher mortality rate (26.2% vs. 15.7%,

p

< 0.001) and longer hospital stays (median: 15 days, IQR: 10–24 vs. 13, IQR: 9–20, and

p

< 0.001). DPs were admitted to the ICU more frequently (15.7% vs. 11.0%,

p

< 0.001) and required mechanical ventilation more often (15.5% vs. 11.3%,

p

< 0.001). In a multivariate logistic regression, factors associated with a higher risk of death were age >65 years, glycaemia >10 mmol/L, CRP and D-dimer level, prehospital insulin and loop diuretic use, presence of heart failure, and chronic kidney disease. Factors contributing to lower mortality were in-hospital use of statin, thiazide diuretic, and calcium channel blocker. Conclusion. In this large COVID-19 cohort, DPs constituted more than a quarter of hospitalized patients. The risk of death and other outcomes compared to nondiabetics was higher in this group. We identified a number of clinical, laboratory, and therapeutic variables associated with the risk of hospital death in DPs.
Using Artificial Intelligence to Develop a Multivariate Model with a Machine Learning Model to Predict Complications in Mexican Diabetic Patients without Arterial Hypertension (National Nested Case-Control Study): Metformin and Elevated Normal Blood Pressure Are Risk Factors, and Obesity Is Protective
Authors: Zaizar-Fregoso Sergio A. , Lara-Esqueda Agustin , Hernández-Suarez Carlos M. , Delgado-Enciso Josuel , Garcia-Nevares Arturo , Canseco-Avila Luis M. , Guzman-Esquivel Jose , Rodriguez-Sanchez Iram P. , Martinez-Fierro Margarita L. , Ceja-Espiritu Gabriel , Ochoa-Díaz-Lopez Hector , Espinoza-Gomez Francisco , Sanchez-Diaz Iyari , Delgado-Enciso Ivan 
Published: February 2023

Diabetes mellitus is a disease with no cure that can cause complications and even death. Moreover, over time, it will lead to chronic complications. Predictive models have been used to identify people with a tendency to develop diabetes mellitus. At the same time, there is limited information regarding the chronic complications of patients with diabetes. Our study is aimed at creating a machine-learning model that will be able to identify the risk factors of a diabetic patient developing chronic complications such as amputations, myocardial infarction, stroke, nephropathy, and retinopathy. The design is a national nested case-control study with 63,776 patients and 215 predictors with four years of data. Using an XGBoost model, the prediction of chronic complications has an AUC of 84%, and the model has identified the risk factors for chronic complications in patients with diabetes. According to the analysis, the most crucial risk factors based on SHAP values (Shapley additive explanations) are continued management, metformin treatment, age between 68 and 104 years, nutrition consultation, and treatment adherence. But we highlight two exciting findings. The first is a reaffirmation that high blood pressure figures across patients with diabetes without hypertension become a significant risk factor at

diastolic
>
70

mmHg

(OR: 1.095, 95% CI: 1.078-1.113) or

systolic
>
120

mmHg

(OR: 1.147, 95% CI: 1.124-1.171). Furthermore, people with diabetes with a

BMI
>
32

(overall obesity) (OR: 0.816, 95% CI: 0.8-0.833) have a statistically significant protective factor, which the paradox of obesity may explain. In conclusion, the results we have obtained show that artificial intelligence is a powerful and feasible tool to use for this type of study. However, we suggest that more studies be conducted to verify and elaborate upon our findings.
Acknowledging connections between Reading and Translation Studies: a bibliographical review
Authors: Winfield Claudia Marchese , Tomitch Lêda Maria Braga 
Published: February 2023

This article presents a bibliographical review of cognitive process-oriented research in translation, focusing on the intersection of the areas of Translation Studies (TS) and Reading. The objective of the study is to identify points of contact between the fields in terms of theoretical and methodological aspects. A broader account of process-oriented research in TS is carried out (Ferreira; Schwieter, 2014; Hurtado Albir et al.; 2015 among others), followed by a review of reading and translation (Shreve et al.,1993, and others). Overall, findings indicate that task purpose and translators’ experience influence reading in translation, yet reading, translation, and reading during translation entail parallel processes of a different nature that are associated in reading during translation.