bluuebunny/crossref_metadata_2025_split huggingface dataset:
Patient and provider perspectives of personal health record use: a multisite qualitative study in HIV care settings
Authors: Conti Jennifer , Fix Gemmae M , Javier Sarah J , Cheng Hannah , Perez Taryn , Dunlap Shawn , McInnes Donald Keith , Midboe Amanda M 
Published: April 2023

Abstract
Use of tethered personal health records (PHRs) can streamline care, reduce unnecessary care utilization, and improve health outcomes for people living with human immunodeficiency virus (HIV). Providers play a role in influencing patients’ decision to adopt and use PHRs. To explore patient and provider acceptance and use of PHRs in an HIV care setting, we used a qualitative study design guided by the Unified Theory of Acceptance and Use of Technology. Participants included providers of HIV care, patients living with HIV, and PHR coordinating and support staff in the Veterans Health Administration (VA). Interviews were analyzed using directed content analysis. We interviewed providers (n = 41), patients living with HIV (n = 60), and PHR coordinating and support staff (n = 16) at six VA Medical Centers between June and December 2019. Providers perceived PHR use could enhance care continuity, appointment efficiency, and patient engagement. Yet, some expressed concerns that patient PHR use would increase provider workload and detract from clinical care. Concerns about poor PHR interoperability with existing clinical tools further eroded acceptance and use of PHRs. PHR use can enhance care for patients with HIV and other complex, chronic conditions. Negative provider attitudes toward PHRs may impact providers’ encouragement of use among patients, consequently limiting patient uptake. Multipronged interventions at the individual, institutional, and system level are needed to enhance PHR engagement among both providers and patients.
Testing of a custom, portable drill press to minimize probe misalignment in sap flow sensors
Authors: Beslity Justin , Shaw Stephen B 
Published: April 2023

Abstract
The accurate estimation of plant transpiration is critical to the fields of hydrology, plant physiology and ecology. Among the various methods of measuring transpiration in the field, the sap flow methods based on head pulses offers a cost-effective and energy-efficient option to directly measure the plant-level movement of water through the hydraulically active tissue. While authors have identified several possible sources of error in these measurements, one of the most common sources is misalignment of the sap flow probes due to user error. Though the effects of probe misalignment are well documented, no device or technique has been universally adopted to ensure the proper installation of sap flow probes. In this paper we compare the magnitude of misalignment errors among a 5 mm thick drilling template (DT), a 10 mm thick DT, and a custom designed, field-portable drill press. The different techniques were evaluated in the laboratory using a 7.5 cm wood block and in the field, comparing differences in measured sap flow. Based on analysis of holes drilled in the wood block, we found that the portable drill press was most effective in assuring that drill holes remained parallel, even at 7.5 cm depth. In field installations, nearly 50% of holes drilled with a 5 mm template needed to be redrilled while none needed to be when drilled with the drill press. Widespread use of a portable drill press when implementing the heat pulse method would minimize alignment uncertainty and allow a clearer understanding of other sources of uncertainty due to variability in tree species, age, or external drivers or transpiration.
Development and engineering application of integrated safety monitoring systems for China's high-speed trains
Authors: Zhu Yan , Wang Tiantian , Shen Ruiyuan , Xie Jingsong , Yang Jingsong , Zhang Guoqin , Tian Hongqi , Liang Xifeng 
Published: April 2023

Abstract
With the improvement of the running speed of China's high-speed trains, the demands for running status monitoring and security assurance of High-speed Electric Multiple Units (EMU) have increased significantly. However, the current safety monitoring systems are independent, which is not conducive to the comprehensive monitoring and information sharing of the whole vehicle. The temperature monitoring of running gear is insensitive to early failures. How to develop a train operation safety monitoring system with strong engineering implementation and high integration is a key problem to be solved. For the monitoring of running stationarity, frame stability and running gear health of China's high-speed trains, an integrated safety monitoring system framework is designed, and the logic and algorithm for the diagnosis of stationarity, stability and health states of rotating parts are constructed. Monitoring software which fused the temperature, high and low frequency vibration data is developed, and the design and installation of the vibration temperature composite sensors are completed. The research results have realized the integration and comprehensive processing of multiple monitoring systems, completed the improvement from single component and vehicle-level safety monitoring to multi-system, train-level and interactive monitoring. In the process of real vehicle application, the developed monitoring system acquires the vehicle operation status data accurately and in real time. The constructed diagnosis algorithm and logic evaluates the vehicle operation status accurately and in a timely manner, and avoids the progression from fault to accident. The research results show that the integrated safety monitoring system can provide technical support for train operation safety.
Genome Resource of Sclerotinia nivalis Strain SnTB1, a Plant Pathogen Isolated from American Ginseng
Authors: Fan Sanhong , Wang Conghao , Jiang Jinglong , Geng Shishuai , Xu Xiangming , Shang Wenjing , Hu Xiaoping 
Published: April 2023

Sclerotinia fungi are necrotrophic plant pathogens that can infect a wide range of plant species and persist in natural conditions. Sclerotinia nivalis is a recently reported species in Sclerotinia and can cause white rot on many plant species. We obtained the whole genome sequence of S. nivalis strain SnTB1 assembled from Oxford Nanopore reads and further polished with Illumina reads. This assembly consists of 32 contigs with a total length of 50.37 Mb, a contig N50 of 2.74 Mb, a GC content of 39.53%, and a repeat element content of 20.68%. In total, 13,276 candidate protein-coding genes were identified and functionally annotated, including those encoding glycometabolic enzymes, proteolytic enzymes, and potential effectors. This is the first available reference genome resource for S. nivalis. [Formula: see text] Copyright © 2023 The Author(s). This is an open access article distributed under the CC BY-NC-ND 4.0 International license .
A Case of Acute Opioid Withdrawal after Liposuction Surgery in a Patient on Extended-release Buprenorphine
Authors: Bobb Raymond , Malayala Srikrishna V. , Papudesi Bhavani Nagendra , Potluri Deepika 
Published: April 2023

Background
The US Food and Drug Administration approved the once-monthly injectable extended-release buprenorphine product to treat moderate-to-severe opioid use disorders. The patient in our case report had a liposuction procedure and immediately started having opioid withdrawal symptoms after the procedure.

Case Description
The patient is a 27-year-old African-American woman who injects drugs and has morbid obesity. She enrolled in a medications for addiction treatment program and opted to get treated with extended-release buprenorphine monthly injections. She tolerated them well for a span of 6 months. In one clinic visit, she reported opioid withdrawal symptoms and started purchasing and using sublingual buprenorphine from her acquaintances. On review of history, she underwent liposuction surgery and this triggered the opioid withdrawal symptoms. Examining her abdomen revealed surgical scars at the site of the buprenorphine injection and the residual buprenorphine depot was not palpable.
A subcutaneous injection of 300-mg extended release buprenorphine was administered in the right periumbilical area in this clinic visit. The following week, she was doing well and denied any withdrawal symptoms.

Discussion
This is a unique case of “iatrogenic opioid withdrawal” after a fairly common surgical procedure. The extended-release buprenorphine formulation solidifies when it comes into contact with bodily fluids forming a depot. The depot and surrounding adipose tissue may have been removed during the patient’s liposuction procedure, causing an immediate drop in buprenorphine levels leading to acute opioid withdrawal.
This case report highlights the precautions that need to be taken before patients go for a surgical procedure like liposuction.
Association Between Positive Childhood Experiences and Childhood Flourishing Among US Children
Authors: Crouch Elizabeth , Radcliff Elizabeth , Brown Monique J. , Hung Peiyin 
Published: April 2023

ABSTRACT:

Objective:
There has been limited research examining the fostering of positive childhood experiences (PCEs) that could promote flourishing among children. The purpose of this study is to examine the relationship between 7 selected PCEs and the outcome of flourishing, among a nationally based population level survey sample of children aged 6 to 17 years.

Methods:
Data were drawn from the 2018 to 2019 National Survey of Children's Health, with children aged 6 years and older included (n = 40,561). Children were designated as flourishing if they had responses of always or usually to all 3 flourishing items measured by the National Survey of Children's Health, which were (1) showing an interest and curiosity in learning new things, (2) working to finish the task they started, and (3) staying calm and in control when faced with a challenge. To examine the association between PCEs and flourishing, multivariable logistic regression models were used.

Results:
Children who experienced each type of PCE had a higher odds of flourishing: after-school activities (adjusted odds ratio [aOR], 1.81; 95% confidence interval [CI], 1.58–2.07), community volunteer (aOR, 1.63; 95% CI, 1.47–1.80), guiding mentor (aOR, 1.66; 95% CI, 1.39–2.00), resilient family (aOR, 2.35; 95% CI, 2.08–2.67), safe neighborhood (aOR, 1.43; 95% CI, 1.29–1.60), supportive neighborhood (aOR, 1.57; 95% CI, 1.42–1.74), and connected caregiver (aOR, 3.26; 95% CI, 2.93–3.64).

Conclusion:
Findings demonstrating a significant association between PCEs and flourishing have implications for population-wide approaches to improving the prevalence of flourishing among children and youth.
Head-to-head comparison of magnetic resonance elastography-based liver stiffness, fat fraction, and T1 relaxation time in identifying at-risk NASH
Authors: Li Jiahui , Lu Xin , Zhu Zheng , Kalutkiewicz Kyle J. , Mounajjed Taofic , Therneau Terry M. , Venkatesh Sudhakar K. , Sui Yi , Glaser Kevin J. , Hoodeshenas Safa , Manduca Armando , Shah Vijay H. , Ehman Richard L. , Allen Alina M. , Yin Meng 
Published: April 2023

Background and Aims:
The presence of at-risk NASH is associated with an increased risk of cirrhosis and complications. Therefore, noninvasive identification of at-risk NASH with an accurate biomarker is a critical need for pharmacologic therapy. We aim to explore the performance of several magnetic resonance (MR)-based imaging parameters in diagnosing at-risk NASH.

Approach and Results:
This prospective clinical trial (NCT02565446) includes 104 paired MR examinations and liver biopsies performed in patients with suspected or diagnosed NAFLD. Magnetic resonance elastography-assessed liver stiffness (LS), 6-point Dixon-derived proton density fat fraction (PDFF), and single-point saturation-recovery acquisition-calculated T1 relaxation time were explored. Among all predictors, LS showed the significantly highest accuracy in diagnosing at-risk NASH [AUCLS: 0.89 (0.82, 0.95), AUCPDFF: 0.70 (0.58, 0.81), AUCT1: 0.72 (0.61, 0.82), z-score test z >1.96 for LS vs any of others]. The optimal cutoff value of LS to identify at-risk NASH patients was 3.3 kPa (sensitivity: 79%, specificity: 82%, negative predictive value: 91%), whereas the optimal cutoff value of T1 was 850 ms (sensitivity: 75%, specificity: 63%, and negative predictive value: 87%). PDFF had the highest performance in diagnosing NASH with any fibrosis stage [AUCPDFF: 0.82 (0.72, 0.91), AUCLS: 0.73 (0.63, 0.84), AUCT1: 0.72 (0.61, 0.83), |z| <1.96 for all].

Conclusion:
Magnetic resonance elastography-assessed LS alone outperformed PDFF, and T1 in identifying patients with at-risk NASH for therapeutic trials.
The lymph node yield in the initial lateral neck dissection predicts recurrence in the lateral neck of papillary thyroid carcinoma: a revision surgery cohort study
Authors: Yu Shi-Tong , Ge Junna , Wei Zhigang , Sun Baihui , Xiao Zizheng , Li Tingting , Zhang Zhicheng , Chen Weisheng , Lei Shang-Tong 
Published: April 2023

Background:
This study aimed to evaluate the relationship between lateral lymph node yield (LLNY) and the ratio of lateral positive lymph nodes to lymph node yield (LPLR) from initial lateral neck dissection (LND) in patients with papillary thyroid carcinoma (PTC), as well as the risk of recurrence in patients undergoing LND reoperations.

Methods:
This retrospective cohort study enrolled patients with PTC who underwent revision LND between 1 January 2012, and 31 December 2021. The initial and revised clinical data were retrieved. Patient demographics, clinicopathological features, clinical records, and follow-up information were also reviewed. LLNY and LPLR were determined during the initial LND.

Results:
In total, 156 patients with PTC were included in this study, with a median follow-up of 36.5 months; 107 had recurrent lateral neck disease. The optimal LLNY and LPLR cutoff values for recurrent/persistent disease were 24.5 and 32.74%, respectively. The high-risk group (LLNY<25) had the lowest recurrence-free survival rate compared with to moderate-risk group (LLNY≥25, LPLR≥32.74%) and low-risk group (LLNY≥25, LPLR<32.74%) (P<0.001). The moderate-risk group had lower recurrence-free survival than the low-risk group. Multivariate analysis revealed that an LLNY less than 25 in the initial LND was an independent risk factor for recurrence/persistence of lateral neck (P<0.001).

Conclusions:
This study identified that LLNY and LPLR were associated with recurrence/persistence in PTC patients at the time of revision surgery was performed.
The evaluation of pupil diameter by using Sirius before and after phacoemulsification in healthy, diabetic and hypertension patients
Authors: Simsek Ali , Toptan Müslüm 
Published: April 2023

Background:
Pupil size can affect the selection of the ablation region in refractive surgery and intraocular lens design in cataract surgery. Therefore, the evaluation of pupil diameter (PD), one of the anterior segment parameters, is an important component of ophthalmological examination.

Material and methods:
Seventy-one healthy patients, 64 patients with Systemic Hypertension (HT), and 65 patients with Diabetes Mellitus (DM) scheduled for phacoemulsification were included in the study. PD was measured before and one month after surgery using combined Scheimpflug-Placido disk topography (Sirius, CSO Inc.). Preoperative PD values of the groups were compared. The PD of the groups was compared in the 1st month after surgery. Then, preoperative and postoperative pupil diameter values of the groups were compared. The effect of the surgery on the change in pupil diameter (effect value) in the groups was also examined.

Results:
Pre- and postoperative PD only differed significantly between the healthy and DM groups (P = .039 and P = .045, respectively). PD decreased in all three groups after phacoemulsification. Pre-and postoperative PD differed significantly in the healthy group (4.78 ± 0.94 and 3.01 ± 0.48 mm, respectively, P < .05). Pre- and postoperative PD values also differed significantly (4.69 ± 0.84 and 2.95 ± 0.42 mm, respectively, P < .05). In the DM group, Pre- and postoperative PD also differed significantly in the DM group (4.38 ± 1.08 and 2.82 ± 0.43 mm, respectively, P < .05). The effect values of PD changes differed in the healthy, DM, and HT groups (1.95, 1.41, and 2.28, respectively). Phacoemulsification was observed to have a greater effect on PD change in HT patients.

Conclusions:
PD was smaller in DM patients than in the other groups. PD decreased in all three groups after phacoemulsification. This change should be remembered when planning cataract surgery for chronic metabolic patients.
Anti-SOX1 antibodies-positive paraneoplastic neurological syndromes caused by thyroid carcinoma: A case report
Authors: Deng Yazhi , Zhang Xiaobo , Wang Lei , Lu Xuelin , Gao Yunchun , Wu Zhenkai , Zhong Zhenzhen 
Published: April 2023

Rationale:
Paraneoplastic neurological syndromes (PNSs) are a group of neurological diseases caused by distant immune effects of malignant tumors, which often occur in patients with small cell lung cancer but are not prone to occur in patients with thyroid cancer. Anti-Sry-like high mobility group box (SOX)1 antibodies (abs)-associated PNSs caused by thyroid cancer are clinically rarer.

Patient concerns:
A 57-year-old Chinese male patient presented with autonomic neuropathy. A thyroid biopsy revealed the diagnosis of papillary thyroid microcarcinoma. The serum anti-SOX1 abs confirmed positive.

Diagnoses:
A diagnosis of anti-SOX1 antibodies-positive PNS was made.

Interventions:
The patient received total thyroidectomy.

Outcomes:
After total thyroidectomy, the patient’s symptoms resolved quickly, and the serum anti-SOX1 abs test results was negative on re-examination.

Lessons:
Thyroid cancer can cause anti-SOX1 abs-associated PNS with only autonomic neuropathy.
The mediating effects of social support on the association between depression and life satisfaction among patients with schizophrenia or bipolar disorder
Authors: Zhang Min-Zhe , Shi Jun-Xia , Rao Wei-Ming , Chen Rui , Yang Hong-Guang , Wu Neng-Jian , He Qi-Qiang 
Published: April 2023

Patients with schizophrenia or bipolar disorders in community had poor psychosocial functioning, social support, and life satisfaction. However, the interaction effects of social support and depression on life satisfaction remains unclear. Thus, we examined these associations among patients with schizophrenia or bipolar disorder.
This cross-sectional study was conducted from October to December 2020 in Shenzhen, China. Information on social support, depression, and life satisfaction was assessed by standardized questionnaires through a face-to-face interview. Hierarchical multiple regression analysis was performed to estimate the associations of social support and depression with life satisfaction and to explore the mediation effect of social support.
A total of 293 patients aged 39.7 ± 11.1 years (males: 47.1 %) were included in this study. Social support was positively associated with high life satisfaction (explaining 7.2% of the variance), while depression was negatively associated with life satisfaction (explaining 17.8% of the variance). Furthermore, social support mediated 12.5% of the association between depression and life satisfaction.
Social support and depression were significantly associated with life satisfaction in patients with schizophrenia or bipolar disorders. Moreover, social support mediated the association between depression and life satisfaction in this population. Health interventions that benefit social support should be promoted to alleviate the negative impact of depression on their life satisfaction.
Resectable fusiform internal jugular vein aneurysm with vascular excision and bypass with an 8 mm Maquet graft: A case report
Authors: Gong Ting-Sheng , Li Tzong-Shiun 
Published: April 2023

Rationale:
Venous aneurysm is a rare vascular disease. Studies reveal that patients with fusiform internal jugular vein aneurysms are not suitable for embolization.

Patient concerns:
Two treatment options are considered, either bypass the aneurysm via stenting or excision of the lesion site and anastomosis using an artificial graft. The advantages of excision bypass include the absence of endoleak and stent migration; however, a larger wound and longer operation time are required for it.

Diagnoses:
Physical examination revealed a swelling in the right neck area. Head and neck computed tomography was performed for the survey. It revealed a 27.22 × 25.07 × 58.17 mm internal jugular fusiform aneurysm.

Interventions:
Vein excision was performed while using hemoclamps to control inflow and outflow, and a graft was anastomosed for bypass using an 8 mm Maquet graft.

Outcomes:
The wound recovery was favorable, with no signs of infection, and the pain was under control.

Lessons:
The patient had a contrast-enhanced head and neck computed tomography, and the images efficiently diagnosed a venous aneurysm. This patient had refractory pain, which was a significant indication of the operation. We decided by ourselves on the duration of the interval of following up. We used excision and bypassing with graft, and the result was beneficial.
Copious vaginal discharge finally diagnosed as cervical adenocarcinoma: A case report
Authors: Mao Peiyu , Zhang Chen , Wang Xinyan , Yang Huadi 
Published: April 2023

Rationale:
Copious vaginal discharge is a frequent manifestation of reproductive tract infections. However, when little effect can obtain treated as vaginitis, cervical disease should be highly suspected.

Patient concerns:
A 41-year-old woman had suffering from abnormally increased vaginal discharge without any other signs of discomfort for the past 4 years. A lot of medical examinations and treatment of vaginosis were administered, resulting in unclear diagnosis and little effect.

Diagnoses:
Cervical adenocarcinoma.

Interventions:
Gynecological examination, vaginal microbiome culture, and primary cervical cancer screening were negative, and a positron emission tomography revealed an increased 18F-fluorodeoxyglucose metabolism in the local cervix. After a thorough description, the patient demanded a hysterectomy and bilateral salpingo-oophorectomy.

Outcomes:
Histopathological evaluation confirmed adenocarcinoma in situ of the uterine cervix.

Lessons:
The correct diagnosis of symptomatic patients with increased vaginal discharge is challenging. Human papillomavirus-negative patients presenting profuse watery vaginal discharge with an abnormal signal of cervix lesion on positron emission tomography or magnetic resonance imaging should be alert to cervical adenocarcinoma. Deep-seated cervical biopsy, conization, or even hysterectomy is conducive to early diagnosis, treatment and improvement of prognosis.