bluuebunny/crossref_metadata_2025_split huggingface dataset:
Family cohesion predicts long-term health and well-being after losing a parent to cancer as a teenager: A nationwide population-based study
Authors: Birgisdóttir Dröfn , Grenklo Tove Bylund , Kreicbergs Ulrika , Steineck Gunnar , Fürst Carl Johan , Kristensson Jimmie 
Published: April 2023

Background
Parentally bereaved children are at increased risk of negative consequences, and the mediating factors most consistently identified are found to be related to family function after the loss, including cohesion. However, existing evidence is limited, especially with respect to children and youths’ own perception of family cohesion and its long-term effects on health and well-being. Therefore, the aim of this study was to investigate self-reported family cohesion the first year after the loss of a parent to cancer and its association to long-term psychological health and well-being among young adults that were bereaved during their teenage years.

Method and participants
In this nationwide population-based study, 622 of 851 (73%) young adults (aged 18–26) responded to a study-specific questionnaire six to nine years after losing a parent to cancer at the age of 13 to 16. Associations were assessed with modified Poisson regression.

Results
Bereaved youth that reported poor family cohesion the first year after losing a parent to cancer had a higher risk of reporting symptoms of moderate to severe depression six to nine years after the loss compared to those reporting good family cohesion. They also had a higher risk of reporting low levels of well-being, symptoms of anxiety, problematic sleeping and emotional numbness once a week or more at the time of the survey. These results remained statistically significant after adjusting for a variety of possible confounding factors.

Conclusion
Self-reported poor family cohesion the first year after the loss of a parent to cancer was strongly associated with long-term negative psychological health-related outcomes among bereaved youth. To pay attention to family cohesion and, if needed, to provide support to strengthen family cohesion in families facing bereavement might prevent long-term suffering for their teenage children.
Household food insecurity and associated factors in South Ari district, Southern Ethiopia: A community-based cross-sectional study
Authors: Toma Temesgen Mohammed , Andargie Kassahun Tamene , Alula Rahel Abera , Kebede Bahiru Mulatu , Gujo Mintesinot Melka 
Published: April 2023

Background
Household food insecurity is a major public health problem in Ethiopia despite the presence of various interventions implemented by the government. However, there is a dearth of evidence regarding the prevalence and responsible factors in Ethiopia, specifically in the South Ari district. This study, therefore, aimed to assess household food insecurity and associated factors in South Ari district, Southern Ethiopia.

Methods
A community-based cross-sectional study was employed from March 11 to April 11, 2021, at South Ari district, Southern Ethiopia. A two-stage sampling technique was used to draw a sample of 717 households. Data were checked and entered into Epi-Data V3.2., and exported to SPSS V25.0 for data exploration and analysis. Variables with a p-value <0.25 in bivariable logistic regression were candidates for multivariable logistic regression. Multivariable logistic regression analysis was fitted to determine factors associated with household food insecurity. Hosmer–Lemeshow goodness-of-fit statistic was used to check model fitness and was satisfied. Adjusted odds ratio (AOR) with a 95% confidence interval (CI) was used to determine the strength of association. P-value <0.05 was used to declare statistical significance.

Result
The prevalence of household food insecurity was 44.8% (95% CI: 41.1%, 48.5%). Larger family size (8 and above) (AOR = 1.91, 95% CI: 1.10, 3.30), high dependency ratio (AOR = 2.71, 95% CI: 1.67, 4.40), medium dependency ratio (AOR = 1.72, 95% CI: 1.13, 2.62), poor wealth index (AOR = 2.30, 95% CI: 1.53, 3.46), not using agricultural extension service (AOR = 2.25, 95% CI: 1.57, 3.23), and non-beneficiary of productive safety net program (AOR = 1.71, 95% CI: 1.01, 2.87) were factors significantly associated with household food insecurity.

Conclusions
The findings of this study showed a significant proportion of households were food insecure in South Ari District. Larger family size, high and medium dependency ratio, poor wealth index, not using agricultural extension service, and non-beneficiary of productive safety net program were significant risk factors associated with household food insecurity. Therefore, rigorous work is highly needed to enhance income-generating activities, strengthen agricultural productivity, expand the productive safety net program, and limit population pressure through improved family planning use.
BERDAKWAH SAMBIL MERAWAT KELUARGA: Aktivitas Khurūj Jama’ah Tabligh Keamiran Metro Lampung pada Masa Pandemi
Authors: Santoso Dri , Syarifudin Ahmad 
Published: April 2023

Khuruj is a Tablighi Jamaat program that requires members to leave their homes for a period of time in order to proselytize Islam's principles. According to some academics, khuruj has resulted in the ignoring of some married couple rights and obligations. Due to the restriction of social movement during the covid-19, khuruj was performed with some adjustments to avoid the transmission of coronavirus. The purpose of this study is to determine the impact of khurûj on family function among Tablighi Jamaat in Metro Lampung during the pandemic era. This article argues that Tablighi Jamaat in Metro City is divided into two factions, namely Tablighi Jamaat Keamiran and Tablighi Jamaat Syuro Alami. Tablighi Jamaat Keamiran still performs Khurûj throughout the pandemic. From the perspective of family function, the researcher discovered Tablighi Jamaat Keamiran, which has been running on Khurûj in a pandemic situation, does not allow the members of Tablighi to Khurûj while disregarding family members. They must prepare for all the requirements of the family. Khuruj adalah program Jamaah Tabligh yang mengharuskan anggotanya meninggalkan rumah mereka untuk jangka waktu tertentu untuk menyebarkan ajaran Islam. Beberapa riset menunjukkan bahwa khuruj telah berakibat pada pengabaian beberapa hak dan kewajiban pasangan suami isteri. Dalam masa pandemi, akibat pembatasan gerakan sosial selama masa covid-19, khuruj dilakukan dengan beberapa penyesuaian untuk menghindari penularan virus corona. Tujuan dari penelitian ini adalah untuk mengetahui dampak khurûj terhadap fungsi keluarga di kalangan Jamaah Tabligh di Metro Lampung pada masa pandemi. Artikel ini berpendapat bahwa Jamaah Tabligh di Kota Metro terbagi menjadi dua kubu, yaitu Jamaah Tabligh Keamiran dan Jamaah Tabligh Syuro Alami. Jamaah Tabligh Keamiran tetap melaksanakan Khurj selama masa pandemi. Ditinjau dari fungsi keluarga, peneliti menemukan Jamaah Tabligh Keamiran yang selama ini menjalankan Khurj dalam situasi pandemi, tidak membolehkan anggota Tabligh untuk Khurj jika dilakukan dengan mengabaikan anggota keluarga. Mereka harus mempersiapkan semua kebutuhan keluarga.
PERFECTION OF SEX FOR THE INTERSEX (KHUNṠA) TO GET MARRIED: Maqāṣid Syarīah Perspective on Corrective Surgery
Authors: April Muhammad , Saiin Asrizal 
Published: April 2023

This paper sheds light on the reasons for performing corrective surgery for intersex person to get married. The data were collected through the examination of works on intersex. The results of this study reveal that Islamic law, following the maqāṣid syarīah approach, allows the intersex person to perform corrective surgery with/without the intention of marriage. The choice to conduct corrective surgery does not violate the five principles of maqāṣid syarīa: the principle of religion (ḥifẓ ad-dīn), the principle of the soul (ḥifẓ an-nafs), the principle of mind (ḥifẓ al-‘aql), the principle of descent (ḥifẓ an-nasl), and the principle of property (ḥifẓ al-māl). However, corrective surgery is limited to the people who biologically have sexual disorders and the surgery must be safe according to medical science.Artikel ini menjelaskan alasan melakukan operasi kelamin bagi orang interseks untuk menikah. Data dalam penelitian ini dikumpulkan dengan cara menelaah berbagai literatur yang membahas interseks. Hasil penelitian ini mengungkapkan bahwa berdasarkan pendekatan maqāṣid syarīah, hukum Islam membolehkan orang interseks melakukan operasi penyempurnaan kelamin, baik disertai niat untuk menikah maupun tidak terlebih dahulu. Pilihan untuk melakukan operasi penyempurnaan kelamin tidak melanggar kelima prinsip maqāṣid syarīah, yakni prinsip agama (ḥifẓ ad-dīn), prinsip jiwa (ḥifẓ an-nafs), prinsip akal (ḥifẓ al-‘aql), prinsip keturunan (ḥifẓ an-nasl), dan prinsip harta (ḥifẓ al-māl).Namun, operasi penyempurnaan kelamin hanya dapat dilakukan bagi orang yang memang benar-benar secara biologis mengalami kelainan seksual. Dan operasi yang dilakukan harus memenuhi standar ilmu kedokteran.
THE NARRATIVE OF PROTECTING POLYGAMOUS WOMEN IN INDONESIA'S DIGITAL WORLD: Between Moderate and Conservative Muslims
Authors: Hadi Mukhammad Nur 
Published: April 2023

This article focuses on the narrative of the polygamy issue on four Indonesian Islamic websites: portal-islam.id, nu.or.id, rumaysho.com, and muslim.or.id. They are selected based on ranking and visitation by referring to the results of processing data on similarweb. Deploying a content analysis approach, this article looks at the extent to which moderate and conservative school websites display the legal narrative of polygamy on their platforms. This research shows that there is a reasonably intense contestation between conservative and moderate perspectives on Islamic websites on the issue of polygamy. Both use the excuse of protecting women as the fundamental argument. Moderate Islamic website such as nu.or.id criticizes conservative understanding but also shows some views that align with traditional schools. The conservative Islamic websites: portal-islam.id, rumaysho.com, and muslim.or.id mostly stand firmly on the traditional argument, polygamy means protecting women. I argue that in this position, the moderate and the conservative Islamic websites, at the top of the rankings do not significantly impact the progressivity of the polygamy legal discourse movement in the digital discourse.[Artikel ini berfokus pada narasi isu poligami di empat situs web Islami Indonesia: portal-islam.id, nu.or.id, rumaysho.com, dan muslim.or.id. Mereka diseleksi berdasarkan ranking dan visitasi dengan mengacu pada hasil pengolahan data pada similarweb. Menggunakan pendekatan analisis konten, artikel ini melihat sejauh mana situs web Islami bernuansa moderat dan konservatif menampilkan narasi hukum poligami di platform mereka. Penelitian ini menunjukkan bahwa terdapat kontestasi antara perspektif konservatif dan moderat dalam situs web Islami tentang isu poligami. Keduanya menggunakan dalih melindungi perempuan sebagai argumen dasar. Situs web Islami beraliran moderat, yakni nu.or.id mengkritisi pemahaman konservatif, tetapi juga menunjukkan beberapa pandangannya berkelindan dengan aliran tradisional. Situs web Islami yang konservatif: portal-islam.id, rumaysho.com, dan muslim.or.id sebagian besar berdiri teguh pada argumen tradisional, yakni poligami berarti melindungi perempuan. Saya berargumen bahwa dalam posisi ini, situs-situs web Islami moderat dan konservatif, di peringkat teratas tidak berdampak signifikan terhadap progresivitas gerakan wacana hukum poligami dalam wacana digital.]
Fulminant Eosinophilic Myocarditis Without Peripheral Eosinophilia
Authors: Lee Ja-Yeon , Lee Sun Hwa , Kim Won Ho 
Published: April 2023

Abstract
Eosinophilic myocarditis is a rare form of myocarditis characterized by eosinophilic infiltration and usually associated with peripheral hypereosinophilia. The clinical spectrum of eosinophilic myocarditis ranges widely, from mildly symptomatic to fulminant disease. When patients have fulminant eosinophilic myocarditis, high-dose corticosteroids can lead to dramatic improvement and peripheral eosinophil counts are used as an indicator of response to treatment. However, in some patients, peripheral eosinophilia is absent at initial presentation; reaching a diagnosis and determining treatment response can be challenging in this situation. This report describes a patient with fulminant eosinophilic myocarditis who initially presented with a normal peripheral eosinophil count, was diagnosed through an early endomyocardial biopsy, and was successfully treated with corticosteroids. Endomyocardial biopsy should be performed to confirm the presence of myocardial eosinophilic infiltration, especially for patients who present with fulminant myocarditis, even when peripheral eosinophilia is absent.
Hepatogomax Improves Serum Albumin and Transaminase Enzyme Activity Levels in Sprague Dawley Rats Liver Cirrhosis
Authors: Kusuma Refani Alycia , Noer Etika Ratna , Purnomo Hery Djagat , Pramono Adriyan , Mahati Endang , Nissa Choirun 
Published: April 2023

ABSTRACTBackground: Patients with liver cirrhosis had liver cell damage and malnutrition risk. Hepatogomax enteral formula consists of soybean flour and goat’s milk flour which could reduce serum albumin, AST, and ALT levels because it contains BCAA amino acids (valine, leucine, and isoleucine) and MCT.Objective: To examine the effect of Hepatogomax enteral formula based on Soybean flour and goat’s milk flour on serum albumin, AST, and ALT levels in Sprague Dawley rats liver cirrhosis.Methods: The true experimental study – pre-post control group used 24 adult Sprague Dawley rats in 4 groups. Groups K(+), P1, and P2 were induced by Thioacetamide 400 mg/kgBW. The groups of P1 and P2 were given the Hepatogomax enteral formula made from soybean flour and goat’s milk flour at a dose of 4.87 g/200gBW and 14.6 g/200gBW for 28 days. Serum albumin levels were determined using the Bromocresol Green (BCG) method while serum AST and ALT were determined using spectrophotometry. Statistical analysis had used Paired T-Test and Kruskal Wallis test with Mann Whitney follow-up test.Results: Serum albumin, AST, and ALT levels in the P1 and P2 groups had significant differences (p<0.05) against the K(-) and K(+) groups. Enteral formula based on soybean flour and goat’s milk flour could increase serum albumin levels and reduce serum AST and ALT levels of P1 and P2 groups. The most significant improvement in serum albumin, AST, and ALT levels was at dose 14.6 g/200gBW.Conclusion: Hepatogomax enteral formula based on Soybean flour and goat’s milk flour could increase serum albumin and redue AST, and ALT levels Sprague Dawley rats liver cirrhosis.
Effects of pegylated recombinant human granulocyte colony-stimulating factor on lymphocytes and white blood cells of patients with malignant tumor
Authors: Zhao Tong , Wang Yuejun , Zhou Deqing , Zhang Weike 
Published: April 2023

Abstract
We investigated the effect of pegylated recombinant human granulocyte colony-stimulating factor (PEG-rhG-CSF) on lymphocytes and white blood cells of patients with malignant tumors. After PEG-rhG-CSF treatment, the count of lymphocytes increased in 66 cases, remained unchanged in 2 cases, and decreased in 20 cases. The difference in lymphocyte count before and after treatment was statistically significant (P < 0.001). White blood cell changes were positively correlated with lymphocyte changes (r = 0.36, P = 0.001). In the subgroup with increased white blood cells (n = 80), there were 62 cases with increased lymphocytes, 1 case with unchanged lymphocytes, and 17 cases with decreased lymphocytes after PEG-rhG-CSF treatment. There was significant difference in the count of lymphocytes and white blood cells (P < 0.001). In the subgroup with 6 mg of PEG-rhG-CSF (n = 66) and the subgroup with 3 mg of PEG-rhG-CSF (n = 22), the changes of white blood cell and lymphocyte counts before and after treatment were statistically significant (P < 0.001). The two were positively correlated in the 6 mg PEG-rhG-CSF subgroup, with correlation coefficient r = 0.34 (P = 0.002). PEG-rhG-CSF can increase the count of lymphocytes and white blood cells in patients with malignant tumors, and the increase of lymphocytes is positively correlated with the increase of white blood cells.
Biological variation of CA 15-3, CA 125 and HE 4 on lithium heparinate plasma in apparently healthy Caucasian volunteers
Authors: Guillaume Louise , Chapelle Virginie , Deltombe Matthieu , Nevraumont Arnaud , Mairesse Antoine , Maisin Diane , Gruson Damien 
Published: April 2023

Abstract

Objectives
Tumor markers are well-known for being important tools in the support of diagnosis, monitoring of treatment efficacy and follow-up of cancers. CA 125, CA 15-3 and HE 4 have demonstrated potential efficacy in other clinical indications. The main objective was to evaluate the biological variation of these glycoproteins using two different immunoassays in an apparently healthy Caucasian population.

Methods
Nineteen healthy volunteers including 11 women and 8 men were sampled weekly for 5 consecutive weeks. Samples were analyzed in duplicate on Lumipulse® G600II (Fujirebio) and on the Cobas e602 (Roche Diagnostics) analyzers. After assessment of normality, exclusion of outliers and analysis of homogeneity of variance, analytical variation (CVA), within-subject biological variation (CVI) and between-subject biological variation (CVG) were determined using a nested ANOVA.

Results
CVA, CVI and CVG were determined on both analyzers and both genders. For CA 125, the CVA ranges from 1.0 to 3.4%, the CVI from 5.7 to 13.8% and the CVG from 32.2 to 42.9%. For CA 15-3, the CVA is between 1.1 and 3.4%, the CVI between 3.9 and 6.5% and the CVG between 43.7 and 196.9%. Lastly, HE 4 has CVA values between 1.4 and 2.4%, CVI between 5.1 and 10.5% and CVG between 7.1 and 12.6%.

Conclusions
Our study provided updated data on the biological variation of CA 125, HE 4 and CA 15-3. These data allow to improve the clinical interpretation and thus the management of the patient.
Best proximity points in ℱ-metric spaces with applications
Authors: Lateef Durdana 
Published: April 2023

Abstract
The aim of this article is to introduce

α

\alpha

-

ψ

\psi

-proximal contraction in the setting of ℱ-metric space and prove the existence of best proximity points for these contractions. As applications of our main results, we obtain coupled best proximity points on ℱ-metric space equipped with an arbitrary binary relation.
Neuropsychiatric manifestations of Lyme disease
Authors: Paparone Philip W. 
Published: April 2023

Abstract
Lyme disease is a multisystem illness that may affect the central nervous system and subsequently produce mild to severe psychiatric disorders. Physicians who treat patient with Lyme disease need to be aware of its neuropsychiatric symptoms, which may emerge months to years after the initial infection. Prompt diagnosis and effective treatment are needed to avoid the debilitating and possibly irreversible mental illness associated with the neurologic involvement of this spirochetal infection. The author reviews the neuropsychiatric manifestations of Lyme disease and provides diagnostic and therapeutic approaches for the management of the central nervous system disease that may cause them.
A fatal overdose of transdermally administered fentanyl
Authors: Kramer Christopher , Tawney Michael 
Published: April 2023

Abstract
We present a case of fentanyl overdose via mucous membrane absorption. A 31-year-old man presented to the emergency department in respiratory arrest. At intubation, a Duragesic transdermal patch (75 μg/h) was recovered from the buccal cavity. A second fentanyl transdermal patch (75 μg/h) was noted on the right lateral aspect of the thigh. Postmortem blood evaluation returned a venous fentanyl level of 17.2 μg/L. The therapeutic range for analgesic use is 1 μg/L to 3 μg/L. Drug screens were positive for benzodiazepines and cocaine. Mass spectrophotometry/gas chromatography was used to determine fentanyl levels and to confirm drug screen results. Case history, findings at intubation, and high fentanyl blood concentration suggest the cause of respiratory arrest and death was fentanyl overdose.
Small bowel obstruction as a complication of laparoscopic extraperitoneal inguinal hernia repair
Authors: Eugene Jean Renoir , Gashti Mojtaba , Curras Ernesto B. , Schwartz Kenneth , Edwards Joseph 
Published: April 2023

Abstract
Laparoscopic hernia repeair is associated with its own set of complications, such as intra-abdominal organ and vascular injury, gas embolism, penumoperitoneum, small bowel obstruction secondary to trocar site fascial defects, intra-abdominal adhesion, and reaction to synthetic mesh. With the extraperitoneal approach, the abdominal cavity is not violated, thereby eliminating the risks for these complications. However, small bowel obstruction, albeit rarely, do occur with this approach because of inadvertent violation of the peritoneal cavity, or failure to close the peritoneal opening of the hernia sac, as shown in this case presentation.
Effect of deep cryogenic processing cycles on surface roughness, dimensional stability and microstructure of high carbon high chromium tool steel for cutting tool and dies applications
Authors: Lomte Sachin , Deshmukh Ravindra , Sonar Tushar , Ivanov Mikhail , Balasubramanian Visvalingam 
Published: April 2023

Abstract
The main objective of this investigation is to analyze the influence of DCT cycles on microstructural evolution, surface roughness, hardness and dimensional stability of AISI D2 tool steel for cutting tools and dies applications. The cryogenic quenching was done using gaseous nitrogen. The AISI D2 tool steel was subjected to two DCT cycle: DCT-I (Hardening + DCT + tempering) and DCT-II (Hardening + tempering + DCT). The dimensional stability of AISI D2 tool steel was evaluated using standard Navy C-ring test. The coordinate measuring machine (CMM) was employed for the precise measurement of Navy C-ring subjected to different DCT cycle. The surface roughness was evaluated with R

a
(arithmetic mean roughness) and R

t
(total height of roughness profile) values using surface roughness tester. The microstructural features were analyzed using optical (OM) and scanning electron microscopy (SEM). The electrical resistivity and hardness of treated samples were measured using micro-Ohm meter and Vickers microhardness tester. Results showed that AISI D2 tool steel treated with DCT-I cycle exhibited greater surface finish, hardness and dimensional stability compared to DCT-II cycle. It is mainly attributed to the greater precipitation of finer carbides and balancing of tensile-compressive residual stresses.