bluuebunny/crossref_metadata_2025_split huggingface dataset:
Contralateral Biases in Category-selective Areas Are Stronger in the Left Hemisphere than the Right Hemisphere
Authors: Herald Sarah B. , Yang Hua , Duchaine Brad 
Published: April 2023

Abstract
Contralateral bias is a well-known feature of early visual cortex, but how it varies across higher-level, category-selective visual cortex and how much that bias differs between preferred and nonpreferred is unclear. Here, we examined 12 category-selective regions across 4 experiments using peripherally presented faces, bodies, houses, and scenes, to measure the difference in contralateral bias between preferred and nonpreferred stimuli. The results showed a substantial range of contralateral biases across the category-selective regions, similar to prior studies using category-selective stimuli [Silson, E. H., Groen, I. I., & Baker, C. I. Direct comparison of contralateral bias and face/scene selectivity in human occipitotemporal cortex. Brain Structure and Function, 227, 1405–1421, 2022; Gomez, J., Natu, V., Jeska, B., Barnett, M., & Grill-Spector, K. Development differentially sculpts receptive fields across early and high-level human visual cortex. Nature Communications, 9, 788, 2018; Silson, E. H., Groen, I. I. A., Kravitz, D. J., & Baker, C. I. Evaluating the correspondence between face-, scene-, and object-selectivity and retinotopic organization within lateral occipitotemporal cortex. Journal of Vision, 16, 14, 2016; Kay, K. N., Weiner, K. S., & Grill-Spector, K. Attention reduces spatial uncertainty in human ventral temporal cortex. Current Biology, 25, 595–600, 2015; Silson, E. H., Chan, A. W.-Y., Reynolds, R. C., Kravitz, D. J., & Baker, C. I. A retinotopic basis for the division of high-level scene processing between lateral and ventral human occipitotemporal cortex. Journal of Neuroscience, 35, 11921–11935, 2015]. These contralateral biases were stronger in the left hemisphere regions than right, an asymmetry that was unchanged even when participants performed an attentionally demanding task. Thus, corresponding pairs of category-selective regions (e.g., left fusiform face area [lFFA] and right FFA [rFFA]) do not appear to be mirror images of each other; instead, the right hemisphere regions engage in greater integration of information from the two hemifields. The rFFA and right fusiform body area—both located on the right lateral fusiform gyrus—consistently had the weakest contralateral biases. That this asymmetry was most pronounced in the fusiform gyrus may account for why a unilateral lesion to the rFFA but not the lFFA can produce prosopagnosia. Together, our findings demonstrate that category-selective areas show pronounced differences in the extent of their contralateral biases and that a consistent asymmetry in the strength of the contralateral biases exists between the two hemispheres.
Corticocerebellar White Matter Integrity Is Related to Naming Outcome in Post-Stroke Aphasia
Authors: Keser Zafer , Meier Erin L. , Stockbridge Melissa D. , Breining Bonnie L. , Hillis Argye E. , Sebastian Rajani 
Published: April 2023

Abstract
Studies have shown that the integrity of white matter tracts connecting different regions in the left cerebral hemisphere is important for aphasia recovery after stroke. However, the impact of the underlying structural connection between the cortex and the cerebellum in post-stroke aphasia is poorly understood. We studied the microstructural integrity of the cerebellum and the corticocerebellar connections and their role in picture naming. Fifty-six patients with left cerebral infarcts (sparing the cerebellum) underwent diffusion tensor imaging (DTI) and Boston Naming Test. We compared the fractional anisotropy (FA) and mean diffusivity (MD) values of the right and the left cerebellum (lobular gray and white matter structures) and cerebellocortical connections. Recursive feature elimination and Spearman correlation analyses were performed to evaluate the relationship between naming performance and the corticocerebellar connections. We found that the right, relative to left, cerebellar structures and their connections with the left cerebrum showed lower FA and higher MD values, both reflecting lower microstructural integrity. This trend was not observed in the healthy controls. Higher MD values of the right major cerebellar outflow tract were associated with poorer picture naming performance. Our study provides the first DTI data demonstrating the critical importance of ascending and descending corticocerebellar connections for naming outcomes after stroke.
Methodological and Cognitive Biases in Science: Issues for Current Research and Ways to Counteract Them
Authors: Fernández Pinto Manuela 
Published: April 2023

Abstract
Arguments discrediting the value-free ideal of science have left us with the question of how to distinguish desirable values from biases that compromise the reliability of research. In this paper, I argue for a characterization of cognitive biases as deviations of thought processes that systematically lead scientists to the wrong conclusions. In particular, cognitive biases could help us understand a crucial issue in science today: how systematic error is introduced in research outcomes, even when research is evaluated as of good quality. To conclude, I suggest that some debiasing mechanisms have great potential for countering implicit methodological biases in science.
India Ukre Giya: Loss and Change in Light of and in the Shadows of War
Authors: Das Vikram , Cook Matthew A. 
Published: April 2023

Abstract
The Thar Desert is located at the confluence of Sindh, Gujarat, and Rajasthan. The region’s folklore refers to the desert as a sea through which a cast of warriors, merchants, and adventurers traveled. Oral histories connect it with business and subsistence exchanges. These histories tell of crossing the Rann of Kutch (i.e., into India from Pakistan). They illustrate a strong connection between Tharparkar (in the Pakistani province of Sindh) and Gujarat (in India). Even after Partition in 1947, people and goods continued moving back and forth between Tharparkar, Gujarat, and Rajasthan. However, after the India-Pakistan wars of 1965 and 1971, Tharparkar became increasingly disconnected from Gujarat. By the late 1980s, fencing the border resulted in the two areas becoming disconnected. In light of and in the shadows of the 1965 and 1971 wars, the expressions “India ukre giya” (i.e., permanently crossing the border to India) and “harass” (i.e., fear) became common. This article explores these two expressions in relation to “loss” and emotional pain among the people of Tharparkar (i.e., Tharis).
Evaluation of Processes Related to Stratosphere–Troposphere Coupling in GEFSv12 Subseasonal Hindcasts
Authors: Lawrence Zachary D. , Elsbury Dillon , Butler Amy H. , Perlwitz Judith , Albers John R. , Ciasto Laura M. , Ray Eric 
Published: April 2023

Abstract
The representation of the stratosphere and stratosphere–troposphere coupling processes is evaluated in the subseasonal Global Ensemble Forecast System, version 12 (GEFSv12), hindcasts. The GEFSv12 hindcasts develop systematic stratospheric biases with increasing lead time, including a too strong boreal wintertime stratospheric polar vortex. In the tropical stratosphere, the GEFSv12 winds and temperatures associated with the quasi-biennial oscillation (QBO) tend to decay with lead time such that they underestimate the observed amplitudes; consistently, the QBO-associated mean meridional circulation is too weak. The hindcasts predict extreme polar vortex events (including sudden stratospheric warmings and vortex intensifications) about 13–14 days in advance, and extreme lower-stratospheric eddy heat flux events about 6–10 days in advance. However, GEFSv12’s ability to predict these events is likely affected by its zonal-mean circulation biases, which increases the rates of false alarms and missed detections. Nevertheless, GEFSv12 shows stratosphere–troposphere coupling relationships that agree well with reanalysis and other subseasonal forecast systems. For instance, GEFSv12 reproduces reanalysis relationships between polar vortex strength and the Northern Annular Mode in the troposphere. It also exhibits enhanced weeks 3–5 prediction skill of the North Atlantic Oscillation index when initialized during strong and weak polar vortex states compared to neutral states. Furthermore, GEFSv12 shows significant differences in Madden–Julian oscillation (MJO) amplitudes and enhanced MJO predictive skill in week 4 during easterly versus westerly QBO phases, though these results are sensitive to the level used to define the QBO. Our results provide a baseline from which future GEFS updates may be measured.
A Typology of Australian Animal Sentience Recognition Provisions — Enacted and Proposed
Authors: Kotzmann Jane 
Published: April 2023

AbstractAustralia appears to be following the trend in mainly Western countries of recognising animal sentience in the law. This article sets out a typology of animal sentience recognition provisions that have been enacted, or have been proposed, in Australian jurisdictions to date. These include provisions or proposed provisions located in statutory objects, statutory principles, statutory definitions and a treaty. Depending on legislative context, these provisions, and proposed provisions (if enacted), may have different legal consequences. The trend towards legally recognising animal sentience may also signal further positive legal reforms for animals in the future.
Soluble ST2 predicts continuous renal replacement therapy in patients receiving venoarterial extracorporeal membrane oxygenation
Authors: Shao Chengcheng , Cao Yu , Wang Zengtao , Wang Xiaomeng , Li Chenglong , Hao Xing , Wang Liangshan , Du Zhongtao , Yang Feng , Jiang Chunjing , Wang Hong , Hao Yu , Han Junyan , Hou Xiaotong 
Published: April 2023

Objective This study aimed to evaluate the relationship between plasma soluble ST2 (sST2) levels 24 h after extracorporeal membrane oxygenation (ECMO) initiation and continuous renal replacement therapy (CRRT) in patients receiving venoarterial ECMO (V-A ECMO) support. Methods and Results Data of patients who received ECMO support for postcardiotomy cardiogenic shock between January 2017 and July 2019 were retrospectively collected from Beijing Anzhen Hospital, Capital Medical University. Ultimately, 116 patients were included in the present study for analysis. The concentration of sST2 was determined by enzyme-linked immunosorbent assay (ELISA). The log10 sST2 levels were higher in patients undergoing CRRT than those who did not (6.06 vs. 6.22, p = 0.019). Patients undergoing CRRT had a lower survival rate than those who did not (32.8% vs. 67.3%, p < 0.001). In the univariate logistic regression analysis, sST2, HCO3-, lactate, and creatinine levels 24 h after ECMO initiation were related to CRRT ( p < 0.05). In the multivariate logistic regression analysis, HCO3- and sST2 were identified as independent risk factors for CRRT use in patients undergoing ECMO ( p < 0.05). The area under receiver operator characteristic curve (AUC) for sST2 and HCO3- together was 0.72 (95% confidence interval (CI), 0.79–0.91), which was better than those of sST2 or HCO3- alone (0.63 vs. 0.67). Conclusions sST2 and HCO3−levels at 24 h after ECMO initiation were associated with CRRT and could predict CRRT use in postcardiotomy cardiogenic shock patients undergoing ECMO.
Patient and public involvement in research published in the British Journal of Occupational Therapy 2015–2021: A scoping review
Authors: Williamson Ruth , Atkin Helen , Wood Oliver , Thomson Louise , Whitehead Phillip 
Published: April 2023

Introduction: The British Journal of Occupational Therapy ( BJOT) recently introduced a requirement for authors to report Patient and Public Involvement (PPI). The public and people using health and social care services have knowledge which holds value in research beyond use as data. Involvement in research process can help shape the generation of critical evidence informing policies and practices; however, little is known about prior PPI reporting. Method: A scoping review was conducted identifying public involvement in research published in BJOT between 2015 and 2021. An electronic search was conducted using key terms. Data were extracted in duplicate or triplicate using GRIPP2 short form checklist. Results: Twenty-five studies were identified which reported public involvement, this was 6% of research published in BJOT. Patients and public were mainly involved in study steering or advisory groups and their primary activity was developing or piloting study materials. There were low levels of reporting the aim, outcome and critical reflections on involvement activities. Main approaches to involvement were consultation (37%) and collaboration (30%). There was inconsistent use of language and terms. Recommendations: Consistent PPI reporting using Guidance for Reporting Involvement of Patients and the Public (GRIPP 2), critical reflection of impact of PPI, acknowledgement of public contributors, future scoping review investigating impact of BJOT PPI authorship guidelines.
Employing impedance spectroscopy to investigate electrical conduction mechanism in polymer composite blends containing conductive masterbatch: PP/EVA/ (PP-g-MA/MWCNTS)
Authors: Dadashi Parsa , Hashemi Motlagh Ghodratollah 
Published: April 2023

Impedance spectroscopy analysis has been employed to investigate the effect of melt mixing time on electrical conduction mechanism, direct contact or electron tunneling, of a polymer blend using a conductive masterbatch. A novel approach is proposed to correlate the dispersion/distribution states of conductive nanoparticles within the phases, achieved through kinetic control of the conductive masterbatch, and their impedance properties. A blend of polypropylene and ethylene-vinyl acetate copolymer (PP/EVA) was considered as a case study for the matrix. An electrically conductive masterbatch of multiwalled carbon nanotubes (MWCNTs) in polypropylene-grafted-maleic anhydride (PP-g-MA) was added to the blend. The masterbatch in varying amounts was mixed with PP/EVA in a range of 1 min–4.5 min. The co-continuous morphology of the ternary polymer blend was validated via scanning electron microscopy micrographs. The atomic force microscopy (AFM) results showed that as the mixing time of the masterbatch increases the interconnected structures within the conductive interphase decrease. Impedance spectroscopy using alternating current was employed to probe the conduction mechanism in the composite blends. The impedance spectroscopy results revealed that for samples with low mixing time, a dielectric relaxation peak occurs at high frequencies due to the existence of more conductive pathways as a consequence of the interconnected structures of the masterbatch phase. Also, the major contribution of conductance was direct contact in the samples with low mixing times while electron tunneling mechanism was considerable for the samples with high mixing times. Dielectric constant was increased as a result of interfacial polarization boosting with mixing time. The percolation threshold was considerably decreased from 0.95 v% for simultaneous direct mixing method to 0.16 v% for the masterbatch method.
The Burden of Pathological Neonatal Jaundice and Its Determinants in Ethiopia: Systematic Review and Meta-Analysis
Authors: Tsehay Binalfew , Afework Mekbeb 
Published: April 2023

Background Neonatal hyperbilirubinemia is a common clinical problem encountered during the neonatal period, especially in the first week of life. Available clinical guidelines note that early detection and intervention of infants at risk of severe hyperbilirubinemia can facilitate timely and effective prevention of the associated complications. Methods The international databases, PubMed/MEDLINE, EMBASE, CINAHL, Google Scholar, Science Direct, and Cochrane Library, and unpublished reports were systematically searched. Two authors independently extracted all necessary data using a standardized data extraction format. STATA 14 statistical software was employed to analyze the data. The Cochrane Q test statistics and I2 tests were used to assess the heterogeneity between the studies. A random-effect model was computed to estimate the pooled prevalence of pathological neonatal hyperbilirubinemia in Ethiopia. Determinants of neonatal hyperbilirubinemia were analyzed. Results Ten studies fulfilled the inclusion criteria and were included in the meta-analysis. The I2 test result showed high heterogeneity (I2, 98.3%, P = <.001). Using the random effect analysis, the pooled prevalence of neonatal hyperbilirubinemia in Ethiopia was 35.90% (95% confidence interval [CI] [23.79, 48.01]). The results from these studies revealed that the occurrence of pathological neonatal hyperbilirubinemia was significantly associated with the presence of ABO blood incompatibility, Rh isoimmunization, neonatal sepsis (odds ratio [OR]: 4.44; CI: 1.72,11.46), birth asphyxia (OR:1.74; CI: 1.08,2.80), low birth weight (OR: 2.22; CI: 1.46,3.31), and prolonged labor (OR: 3.24; CI: 1.05,10.0). Conclusion The burden of neonatal hyperbilirubinemia is higher in our country as compared with others. ABO blood incompatibility, Rh isoimmunization, neonatal sepsis, birth asphyxia, low birth weight, and prolonged labor were significantly associated with neonatal hyperbilirubinemia.
What matters most to cerebral aneurysms patients: A digital analysis of 1127 social media posts
Authors: Gajjar Avi A. , Salem Mohamed M. , Hou Neo Y. , Davis Ryan Michael , Le Anthony Huy Dinh , Jankowitz Brian T. , Burkhardt Jan Karl 
Published: April 2023

Introduction Social media serves as a way for patients to post about their condition online, as well as for healthcare providers to disseminate information. Intrinsic bias exists exist when patients are given surveys by physicians or healthcare providers. We aim to investigate patient-centered social media posts regarding cerebral aneurysms on Instagram, Twitter, and TikTok. Methods Posts that included “brain aneurysm”, “#brainaneurysm”, “#brainaneurysmsurvivor”, and “#aneurysmsurvivor” were queried on Instagram, Twitter, and TikTok. Any posts unrelated to the patient experience were excluded. Five hundred and fourteen Instagram posts, fourty tweets, and five hundred seventy three TikTok posts about the patient experience were identified. Posts were coded for the relevant themes related to their experience with the disease. Results Most posts made online were by women (892, 82.1%). Patients made the post most of the time (776, 67.5%), while other individuals posted less often (420, 36.5%). The most common themes on Instagram were survival (475, 87.3%), spreading positivity (385, 70.77%), and recovery/rehabilitation (329, 60.5%). TikTok users most often referred to survival (573, 97.1%), raising awareness (464. 78.6%), and spreading positivity (414, 70.2%). Patients were more likely to discuss pre-operative pain (p = 0.0382), postoperative pain (p < 0.0001), invisible illness (p = 0.0130), humor (p = 0.0028), recovery (p < 0.0001), angiograms (p < 0.0001), and resiliency (p < 0.0001) when compared to other individuals posting about a patients' experience. Conclusion Patients often focus on different aspects of their care than do other individuals. This may be useful for physicians discussing treatment plans and prognoses with the patient and their families.
Lessons learned from conducting the first cancer care delivery trial in the Alliance for Clinical Trials in Oncology (Alliance A191402CD)
Authors: Pacyna Joel E , Dueck Amylou C , Chang George J , Chow Selina , Paskett Electra D , Kim Simon , Tilburt Jon C 
Published: April 2023

Introduction: Testing healthcare delivery interventions in rigorous clinical trials is a critical step in improving patient care, but conducting multisite randomized clinical trials to test the effect of care delivery interventions has unique challenges and requires foresight and planning. Methods: We conducted the first care delivery trial (A191402CD) in the Alliance for Clinical Trials in Oncology, a National Cancer Institute Community Oncology Research Program research base, which tested the effectiveness of two different decision aids for supporting shared decision-making about prostate cancer treatment. Our experience illustrates the kind of challenges that confront care delivery researchers as they seek to test interventions to improve the experiences of patients. Results: Lessons learned include the following: cluster-randomized designs introduce complexity; workflow disruption can discourage site participation; evidence-based methods may not always be sufficient. Conclusion: We conclude with the following recommendations: assessing feasibility requires special rigor; relationships and interpersonal dynamics must be leveraged. Our experiences may inform future care delivery research.
The pan-immune-inflammation value is associated with clinical outcomes in patients with advanced TNBC treated with first-line, platinum-based chemotherapy: an institutional retrospective analysis
Authors: Provenzano Leonardo , Lobefaro Riccardo , Ligorio Francesca , Zattarin Emma , Zambelli Luca , Sposetti Caterina , Presti Daniele , Montelatici Giulia , Ficchì Angela , Martinetti Antonia , Arata Alessio , Del Vecchio Marta , Lauria Pantano Claudia , Formisano Barbara , Bianchi Giulia Valeria , Capri Giuseppe , de Braud Filippo , Vernieri Claudio , Fucà Giovanni 
Published: April 2023

Background: Advanced triple-negative breast cancer (aTNBC) has a poor prognosis; thus, there is a need to identify novel biomarkers to guide future research and improve clinical outcomes. Objectives: We tested the prognostic ability of an emerging, complete blood count (CBC)-based inflammatory biomarker, the pan-immune-inflammation value (PIV), in patients with aTNBC treated with first-line, platinum-based chemotherapy. Design: This was a retrospective, monocentric, observational study. Methods: We included consecutive aTNBC patients treated with platinum-based, first-line chemotherapy at our Institution, and for whom baseline (C1) CBC data were available. We collected CBC data early on-treatment, when available. PIV was calculated as: (neutrophil count × platelet count × monocyte count)/lymphocyte count. Patients with hormone receptor-positive (HR+), human epidermal growth factor receptor 2 (HER2)-negative advanced breast cancer (aBC) were included in a control, non-TNBC cohort. Results: A total of 78 aTNBC patients were included. When evaluated as a continuous variable, PIV-C1 was associated with worse overall survival (OS; p < 0.001) and progression-free survival (PFS; p < 0.001). On the other hand, when PIV-C1 was assessed on the basis of its quantile distribution, patients with ‘high PIV-C1’ experienced worse OS [adjusted hazard ratio (HR): 4.46, 95% confidence interval (CI): 2.22–8.99; adjusted p < 0.001] and PFS (adjusted HR: 2.03, 95% CI: 1.08–3.80; adjusted p = 0.027) when compared to patients with ‘low PIV-C1’. Higher PIV-C1 was also associated with primary resistance to chemotherapy. Similarly, a higher PIV calculated from CBC at C2D1 (PIV-C2) was associated with worse survival outcomes. We also created a PIV-based score combining information about both PIV-C1 and PIV-C2 and allowing the stratification of patients at low, intermediate, and high risk of death. No association was observed between PIV-C1 and clinical outcomes of HR+/HER2− aBC patients. Conclusion: PIV has a promising prognostic discrimination ability in aTNBC patients treated with first-line, platinum-based chemotherapy. Both baseline and early on-treatment PIV are associated with clinical outcomes and may be exploited for creating PIV-based risk classifiers if further validated.