bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recent Patents on Manufacturing Microtextured Surface
Authors: Pan Chengyi , Yan Yubin , Cao Yuanfei , Shao Ruinan 
Published: February 2023

Background:
Surface microtextured technology is an expansion and extension of biomimicry
in the tribology field, promoting vigorous development in microtextured tribology.
Through artificial means, tiny convex hulls, craters, or stripes of specific size and arrangement are
processed on the friction surfaces to change the morphology and contact angle of the surfaces and
improve the surface contact state or the lubrication effect. The function and properties of microtextured
surfaces are determined by optimizing their geometrical parameters, but the microtextured
geometrical parameters require a high-level machining quality. It is necessary to analyze and summarize
the existing research on manufacturing microtextured surfaces. By summarizing the preparation
methods of microtextured surfaces in the past decade, some valuable conclusions are drawn to
predict the future development of technology for manufacturing microtextured surfaces and provide
a reference for researchers in related fields. This paper summarizes the representative patents related
to the methods of manufacturing microtextured surfaces, analyzes the properties of the microtextured
surfaces produced by each method, and discusses the advantages and disadvantages of these
methods. The existing problems are summarised through the analyses of patents related to microtextured
preparation methods. The future development of new preparation methods has prospected. By
cooperating with various processing technologies and optimizing the processing methods, the microtextured
surfaces can meet various functional requirements, and the manufacturing precision is
higher than before. The processing method needs further improvement according to the working
conditions. More new technologies will be invented to create microtextured surfaces.
Research on CMUTs Design with Different Cell Arrangements
Authors: Cao Xuewen , Yu Yuanyu , Liu Xin , Ma Jingyi , Zhang Hua , Wang Lijia 
Published: February 2023

Background:
Capacitive micromachined ultrasonic transducers (CMUTs) is a promising
component of mechanical-electrical-acoustical conversion, which shows valuable applications in
non-distructive testing and obstacle detection fields. In order to study the influence of dimension
parameters on the directivity of CMUTs, the three-dimensional multi-physics coupling model is
proposed for CMUTs in this paper.

Methods:
The model combines multiple physical fields through finite element method (FEM),
which is more efficient and accurate. The influence of dimension parameters on the transducer is
studied from two aspects: the pitch between adjacent cells and cell number, respectively.

Results:
When increasing the pitch, the directivity becomes better if the pitch is less than half of the
wavelength, the grating lobe and side lobe are aroused. However, the bandwidth at -3dB is reduced
by up to 71.1% at the same time. When increasing the cell number, the better the direcitvity, while
the change of the cell number has little effect on the bandwidth of the array. However, 5.4% frequency
shift was caused due to the effective mass change of the transducer.

Conclusion:
In this study, a 3D model based on FEM is proposed for the influence of dimension
parameter on CMUTs. The simulation results indicate that the directivity can be enhanced by changing
the dimension. At the same time, it also introduces other performance issues, such as bandwidth
decrease and frequency shift through this approach. Therefore, the simulation proposed the guidance
of CMUTs performance optimization and patented technology application work in the future.
Greener Approaches for Synthesis of Bioactive Thiadiazole Scaffolds
Authors: Sahoo Biswa Mohan , Banik Bimal Krishna , Tiwari Abhishek , Tiwari Varsha , Mahapatra Manoj Kumar 
Published: February 2023

Abstract:
Thiadiazole is a paradigm of five membered heterocyclic compound that contains two
nitrogens and one sulphur as heteroatoms with molecular formula C2H2N2S. Thiadiazole is mainly
present in four isomeric forms such as 1,2,3-thiadiazole, 1,2,4-thiadiazole, 1,2,5-thiadiazole and
1,3,4-thiadiazole. Out of these isomers, 1,3,4-thiadiazole has attracted remarkable attention in the
field of medicinal chemistry. Some of the drugs containing 1,3,4-thiadiazole moiety are used clinically
and are available in the market including Sulphamethizole (Antibacterial), Acetazolamide
(Diuretic), Azetepa (Antineoplastic), Cefazolin (Antibiotic), Megazol (Antiprotozoal), Atibeprone
(anti-depressant). Several greener approaches are applied for the synthesis of thiadiazole scaffolds
including microwave irradiation, ultrasonic irradiation, grinding, ball milling technique, etc. These
methods are eco-friendly, nonhazardous, reproducible, and economical approach. Based on these
Green chemistry approaches, thiadiazole derivatives are synthesized from thiosemicarbazide. The
functionalization of these heterocyclic compounds generates thiadiazole derivatives with diverse
chemical structures. This review covers green synthesis, biological potentials, and structure activity
relationship study of thiadiazole analogs.
Cardioprotective Activities of some Indian Spices: An Insight into
Pharmacology and Phytochemical Investigation
Authors: Pathak Kalyani , Pathak Manash Pratim , Saikia Riya , Gogoi Urvashee , Sahariah Jon Jyoti , Das Aparoop , Ahmad Mohammad Zaki , Paul Tirna , Das Jyotirmoy , Alqahtani Saif Aboud M. 
Published: February 2023

Abstract:
Cardiovascular disease (CVD) is the leading cause of death globally, and coronary heart
disease (CHD) is the most prominent one among the spectrum of CVD. Conventional CHD drugs
pose an increased risk of pharmaceutical interactions. Moreover, the possibility of tainting or substituting
other medications also raises concerns. Diet and lifestyle play an important role in preventing
and treating heart disease, and certain spices and supplements can help reduce the risk of heart disease
and treat it. Spices have been an important part of Indian culture from the dawn of time, valued
for both their culinary and medicinal virtues. Indian spices and their bioactive phytoconstituents are
reported to play an ameliorating role in treating CHD. Despite the fact that the majority of these
spices have an effect on organic components associated with the cardiovascular system, data on
their therapeutic effects is sparse. To make the most of the enormous potential of these spices, multidisciplinary
research is the need of the hour to establish them as remedies for CVDs. We endeavour
to document some ethnopharmacological studies aimed to establish the cellular and molecular
cardio-protective mechanisms of the spices and their bioactive phytoconstituents using recently reported
in vitro and in vivo studies. Finally, we reviewed and reported the results of the recent clinical
trials that have been conducted using these spices with special emphasis on their efficacy, safety,
and toxicity.
Pengenalan dan Pelatihan Pengendalian Secara Hayati Larva Nyamuk dengan Bacillus thuringensis var. israelensis Kultur Air Kelapa di Desa Kedungpoh, Kecamatan Nglipar, Kabupaten Gunungkidul
Authors: Kinanti Thiwuk Leres , Sumarmi Siti , Kusumawati Nafisa , Putri Ristiyani Khofifa , Adi Hanindyo , Marsudi Tri 
Published: February 2023

Kegiatan hibah pengabdian kepada masyarakat merdeka kampus merdeka (PKM-MBKM) dilakukan dengan melaksanakan pengenalan dan pengendalian larva nyamuk vektor penyakit dengan menggunakan Bacillus thuringiensis var israelensis (Bti.) yang dibiakkan pada air kelapa di Desa Kedungpoh , Kecamatan Nglipar, Kabupaten Gunung Kidul. Kegiatan pengabdian masyarakat ini diharapkan memberikan informasi cara pengendalian nyamuk secara biologi yang efektif, mudah dan murah. Metode pengaplikasian agen hayati Bti. dilapang adalah dengan melalui pelatihan pembuatan kultur Bti. dan uji efektifitas. Uji efektifitas Bti. kultur air kelapa dengan konsentrasi 0 ppm, 1 ppm, 1,5 ppm dan 2 ppm masing-masing diletakkan di luar dan di dalam rumah warga. Kegiatan monitoring efektifitas Bti. dilakukan melalui jumlah larva yang ada di dalam setiap ember perlakuan pada minggu ke 1, 2, 3. Kegiatan indentifikasi nyamuk dilakukan pada fase imago. Pelatihan diikuti oleh ibu-ibu kader kesehatan (Jumantik). Hasil monitoring menunjukkan bahwa menunjukkan bahwa aplikasi Bti. lebih efektif dalam mengendalikan larva nyamuk pada minggu ke-1 dibandingkan minggu ke-2 dan ke-3. Hasil identifikasi nyamuk yang diperoleh dari sampel menunjukan nyamuk Aedes sp., Culex sp., dan Armigers sp.
Keterlekatan Etika Moral Islam dan Budaya Jawa Petani Kopi Arjuno
Authors: Novianto Putra Ronny Ersya , Wicaksono Harianto , Rahmawati Desy Ayu Nining Dwi 
Published: February 2023

Penelitian ini bertujuan untuk: (a) menggambarkan tipologi nilai etika moral Islam dan Jawa pada tindakan ekonomi petani kopi Arjuno, (b) menggambarkan pembentukan jaringan, relasi ekonomi, nilai, norma dan tindakan ekonomi individu petani kopi Arjuno dan, (c) keterlekatan etika moral ekonomi Islam dan Jawa dalam tindakan ekonomi petani kopi Arjuno. Penelitian ini menggunakan kualitatif sebagai metode penelitian dengan pendekatan studi kasus, latar tempat dalam penelitian ini perkebunan kopi rakyat lereng gunung Arjuno. Hasil penelitian ini menunjukkan: (a) petani kapitalis Islam dan Jawa memegang teguh tipologi nilai dasar manusia Jawa, nilai “Gak Gelem di ndas-endasi”, petani kopi kapitalis Islam membentuk nilai adil, sabar dan jujur dalam mempertahankan eksistensinya, sementara petani kopi kapitalis Jawa membentuk nilai nerimo ing pandum, eling lan waspodo serta tepo sliro, prasojo lan temen untuk mempertahankan eksistensinya. (b) jaringan dan hubungan ekonomi yang terbentuk intens menguatkan trust antar aktor serta nilai, norma dan tindakan ekonomi individu petani kopi Arjuno bersifat kolektif dan inklusif. (c) keterlekatan etika moral ekonomi Islam dan Jawa dalam tindakan ekonomi petani kopi Arjuno, petani kopi kapitalis Islam mampu berkembang dan membuka tindakan ekonomi bersifat kolaboratif aktif dalam mempertahankan eksistensinya, berbanding terbalik dengan petani kopi kapitalis Jawa.
A Review of Literature and Experimental Evidence on Fraud Motivation: Differentiating Incentive and Pressure
Authors: Knisley Robert J. , Lin Hui 
Published: February 2023

ABSTRACT
This study reviews academic and professional literature on the two types of fraud motivation: incentive and pressure, and provides an in-depth analysis to investigate and differentiate incentive and pressure. The evolution of the professional standards on fraud reveals the need to differentiate incentive and pressure to mitigate fraud. A comprehensive review of academic research uncovers a plethora of fraud research that has studied incentive and pressure either discretely or without differentiation. Few studies have focused on examining and comparing them simultaneously. Theoretically grounded in the fraud triangle and motivation literature, this study synthesizes prior research on incentive and pressure, analyzes the differences by levels of autonomy and regulation. An experiment was conducted and results reveal that incentive and pressure differ in their role in influencing fraudulent intention. Incentive appears to be stronger in influencing fraud intention than pressure. We present the research implications and outline an agenda for future research.
Proinsulin–to–C-Peptide Ratio as a Marker of β-Cell Function in African American and European American Adults
Authors: Couch Catharine A. , Piccinini Francesca , Fowler Lauren A. , Garvey W. Timothy , Gower Barbara A. 
Published: February 2023

OBJECTIVE
The primary purpose of the current study was to test the hypothesis that the proinsulin–to–C-peptide (PI-to-CP) ratio, as an index of proinsulin secretion, would be higher and associated with indices of β-cell function in African American adults relative to European American adults without type 2 diabetes.

RESEARCH DESIGN AND METHODS
Participants were 114 African American and European American adult men and women. A 2-h oral glucose tolerance test was conducted to measure glucose, insulin, C-peptide, and proinsulin and derive indices of β-cell response to glucose. The Matsuda index was calculated as a measure of insulin sensitivity. The disposition index (DI), the product of insulin sensitivity and β-cell response, was calculated for each phase of β-cell responsivity. Pearson correlations were used to investigate the relationship of the PI-to-CP ratio with each phase of β-cell response (basal, Φb; dynamic, Φd; static, Φs; total, Φtot), disposition indices (DId, DIs, DItot), and insulin sensitivity. Multiple linear regression analysis was used to evaluate independent contributions of race, BMI, and glucose tolerance status on PI-to-CP levels before and after adjustment for insulin sensitivity.

RESULTS
African American participants had higher fasting and 2-h PI-to-CP ratios. The fasting PI-to-CP ratio was positively associated with Φb, and the fasting PI-to-CP ratio and 2-h PI-to-CP ratio were inversely associated with DId and insulin sensitivity only in African American participants.

CONCLUSIONS
The PI-to-CP ratio could be useful in identifying African American individuals at highest risk for β-cell dysfunction and ultimately type 2 diabetes.
Safety and Efficacy of the Omnipod 5 Automated Insulin Delivery System in Adults With Type 2 Diabetes: From Injections to Hybrid Closed-Loop Therapy
Authors: Davis Georgia M. , Peters Anne L. , Bode Bruce W. , Carlson Anders L. , Dumais Bonnie , Vienneau Todd E. , Huyett Lauren M. , Ly Trang T. 
Published: February 2023

OBJECTIVE
Automated insulin delivery (AID) has rarely been studied in adults with type 2 diabetes. We tested the feasibility of using AID for type 2 diabetes with the Omnipod 5 System in a multicenter outpatient trial.

RESEARCH DESIGN AND METHODS
Participants previously were using either basal-only or basal-bolus insulin injections, with or without the use of a continuous glucose monitor (CGM), and had a baseline HbA1c ≥8% (≥64 mmol/mol). Participants completed 2 weeks of CGM sensor data collection (blinded for those not previously using CGM) with their standard therapy (ST), then transitioned to 8 weeks of AID. Participants who previously used basal-only injections used the AID system in manual mode for 2 weeks before starting AID. Antihyperglycemic agents were continued at clinician discretion. Primary safety outcomes were percentage of time with sensor glucose ≥250 mg/dL and &lt;54 mg/dL during AID. Additional outcomes included HbA1c and time in target range (TIR) (70–180 mg/dL).

RESULTS
Participants (N = 24) had a mean (± SD) age of 61 ± 8 years, baseline HbA1c of 9.4% ± 0.9% (79 ± 10 mmol/mol), and diabetes duration of 19 ± 9 years. Percentage of time with sensor glucose ≥250 mg/dL decreased with AID by 16.9% ± 16.2% (P &lt; 0.0001), whereas percentage of time at &lt;54 mg/dL remained low during both ST and AID (median [interquartile range] 0.0% [0.00%, 0.06%] vs. 0.00% [0.00%, 0.03%]; P = 0.4543). HbA1c (± SD) decreased by 1.3% ± 0.7% (14 ± 8 mmol/mol; P &lt; 0.0001) and TIR increased by 21.9% ± 15.2% (P &lt; 0.0001) without a significant change in total daily insulin or BMI with AID.

CONCLUSIONS
Findings from this feasibility trial of AID in adults with type 2 diabetes with suboptimal glycemic outcomes justify further evaluation of this technology in this population.
Glomerular Hyperfiltration Predicts Kidney Function Decline and Mortality in Type 1 and Type 2 Diabetes: A 21-Year Longitudinal Study
Authors: Moriconi Diego , Sacchetta Luca , Chiriacò Martina , Nesti Lorenzo , Forotti Giovanna , Natali Andrea , Solini Anna , Tricò Domenico 
Published: February 2023

OBJECTIVETo evaluate the prognostic value of glomerular hyperfiltration on long-term kidney-related outcomes and mortality in patients with diabetes.RESEARCH DESIGN AND METHODSWe retrospectively analyzed 21-year longitudinal data from 314 patients with long-standing type 1 or type 2 diabetes. Glomerular hyperfiltration was identified based on the age- and sex-specific distribution of measured glomerular filtration rate (mGFR) by 99mTc-DTPA dynamic renal scintigraphy. The primary outcome was a composite of doubling of serum creatinine, end-stage kidney disease (ESKD), or cardiorenal death. The kidney-specific outcome was a composite of doubling of serum creatinine, ESKD, or renal death.RESULTSOver a median of 21.0 years, the primary composite outcome occurred in 25 (39.7%), 24 (38.1%), and 46 (24.5%) participants with high mGFR (H-mGFR) (n = 63), low mGFR (L-mGFR) (n = 63), or normal mGFR (N-mGFR) (n = 188), respectively. Compared with N-mGFR, the hazard ratio (HR) for the primary composite outcome was 2.09 (95% CI 1.25–3.49) in H-mGFR and 1.81 (1.05–3.16) in L-mGFR. The HR for the kidney-specific composite outcome was 4.95 (2.21–11.09) in H-mGFR and 3.81 (1.70–8.56) in L-mGFR. The HRs for doubling of serum creatinine and cardiorenal death were 4.86 (2.18–10.90) and 2.18 (1.24–3.83) in H-mGFR and 4.04 (1.77–9.20) and 2.26 (1.27–4.01) in L-mGFR, respectively.CONCLUSIONSGlomerular hyperfiltration, similar to hypofiltration, increases the combined risk of worsening kidney function and mortality from cardiovascular or renal causes in patients with diabetes. These findings encourage the active screening of these patients to optimize risk stratification and treatment of subclinical kidney disease.
Effects of Intensive Systolic Blood Pressure Lowering on End-Stage Kidney Disease and Kidney Function Decline in Adults With Type 2 Diabetes Mellitus and Cardiovascular Risk Factors: A Post Hoc Analysis of ACCORD-BP and SPRINT
Authors: Tawfik Yahya M.K. , Van Tassell Benjamin W. , Dixon Dave L. , Baker William L. , Fanikos John , Buckley Leo F. 
Published: February 2023

OBJECTIVETo determine the effects of intensive systolic blood pressure (SBP) lowering on the risk of major adverse kidney outcomes in people with type 2 diabetes mellitus (T2DM) and/or prediabetes and cardiovascular risk factors.RESEARCH DESIGN AND METHODSThis post hoc ACCORD-BP subgroup analysis included participants in the standard glucose-lowering arm with cardiovascular risk factors required for SPRINT eligibility. Cox proportional hazards regression models compared the hazard for the composite of dialysis, kidney transplant, sustained estimated glomerular filtration rate (eGFR) &lt;15 mL/min/1.73 m2, serum creatinine &gt;3.3 mg/dL, or a sustained eGFR decline ≥57% between the intensive (&lt;120 mmHg) and standard (&lt;140 mmHg) SBP-lowering arms.RESULTSThe study cohort included 1,966 SPRINT-eligible ACCORD-BP participants (40% women) with a mean age of 63 years. The mean SBP achieved after randomization was 120 ± 14 and 134 ± 15 mmHg in the intensive and standard arms, respectively. The kidney composite outcome occurred at a rate of 9.5 and 7.2 events per 1,000 person-years in the intensive and standard BP arms (hazard ratio [HR] 1.35 [95% CI 0.85–2.14]; P = 0.20). Intensive SBP lowering did not affect the risk of moderately (HR 0.96 [95% CI 0.76–1.20]) or severely (HR 0.92 [95% CI 0.66–1.28]) increased albuminuria. Including SPRINT participants with prediabetes in the cohort did not change the overall results.CONCLUSIONSThis post hoc subgroup analysis suggests that intensive SBP lowering does not increase the risk of major adverse kidney events in individuals with T2DM and cardiovascular risk factors.
PENDIDIKAN AKHLAK MULIA MELALUI MAJLIS ZIKIR
Authors: Rahman Abd. 
Published: February 2023

Pendidikan akhlak mulia terhadap manusia bukanlah pekerjaan ringan. Maka dari itu, majlis zikir perlu diperhatikan secara intensif dan harus diberikan waktu tertentu dan terpenting adalah aplikasinya. Adapun aplikasi zikir ada tiga yaitu: 1. Zikir Qalbiyah (hati) maksudnya adalah segalah sesuatu yang akan dilaksanakan harus berawal pada kesucian hati dan keikhlasan niat untuk Allah Swt. 2. Zikir Qauliyah (ucapan) maksudnya adalah segala ucapan yang akan dikeluakan pada lisan harus bermanfaat pada diri sendiri dan orang lain. 3. Zikir Fi’liyah (perbuatan) maksudnya adalah segala perbuatan dan pergaulan harus dijaga dalam kehidupan sehari-harinya.
Akhlak mulia akan membawa manfaat pada Qalb (hati), agar tetap hidup bersih dan bercahaya. Sebab hati yang hidup dan bercahaya akan menjadi modal segala kebaikan, kesuksesan dan keselamatan hidup di dunia dan akhirat. Karena dasar segala kebaikan dan keselamatan khamba adalah hati yang bersih dan bercahaya, bahkan setiap makhluk hidup adalah kesempurnaan hidup dan cahayanya. Allah Swt telah menghimpun dua dasar yakni kehidupan dan cahaya. Hidup akan melahirkan kekuatan pendengaran, penglihatan, malu, keberanian, kesabaran dan segenap akhlak mulia lainnya.
Dengan berakhlak mulia, manusia akan memperoleh beberapa manfaat dari akhlaknya yakni; a) agamanya semakin kuat, b) dimudahkan perhitungan amalnya pada yaumul hisab (hari perhitungan amal), c) Ketika mendapat kesulitan selalu juga mendapat solusi dari Allah Swt, d) dijamin keselamataanya disunia dan akhirat.
The Cuban Rafter Crisis on Stage: Humanizing the Experience of Refugees in María Irene Fornés’ Manual for a Desperate Crossing
Authors: Crespán Araceli González 
Published: February 2023

Abstract
The Cuban-born playwright María Irene Fornés (1930-2018) repeatedly dealt with migration in several plays throughout her long career in theater, sometimes presenting characters who were immigrants living in New York (Sarita) or resorting to correspondence between distant relatives separated in different countries (La Viuda, Letters from Cuba). Manual for a Desperate Crossing was her response to the Cuban Rafter Crisis of the mid-1990s. The article analyzes how the playwright makes use of a combination of objective and subjective strategies to counteract the dehumanizing effect of media coverage, shifting the focus to the individuals who risked their lives in the perilous crossing of the Caribbean Sea in rickety rafts from Cuba to the Florida shores. The emphasis on the transit as a theme and the mixture of instructional, technical discourses with highly stylized stage design and different audiovisual media forces us to look in a different, immersive way that generates empathy towards the refugees.
The Activism of Dance Performance in Appalachia: Utilizing the Arts to Address Social and Environmental Crisis and Injustice in the Mountains
Authors: Burriss Theresa L. 
Published: February 2023

Abstract
For well over a century, the human and more-than-human of Central Appalachia have endured oppression and exploitation, primarily due to natural resource extraction. In spring 2008, the author led a dark touri to a mountaintop removal coalmining site in Southern West Virginia for colleagues, which included Dance Professor Deborah McLaughlin. As a result, the two collaborated on three evening-length dance/theater works highlighting social and environmental crises and injustices in the region. The performances incorporated contemporary dance, poetry, the spoken word, and the visual arts, as well as contemporary and traditional music. The first, Eating Appalachia: Selling Out to the Hungry Ghost, focused on mountaintop removal coalmining and its environmental and cultural destruction. With Sounds of Stories Dancing, the duo paid homage to millions of mountain residents forced to leave the region to find stable employment, despite longing to remain. In the final piece, The Shadow Waltz, they honored the lives of coalminers with black lung disease, as well as their families. This essay discusses the challenges of creating art that critiques socially constructed messages portrayed as given truths, as well as the educational and social successes of daring to dance truth to power.