bluuebunny/crossref_metadata_2025_split huggingface dataset:
Designerly Ways of Entrepreneuring for a Sustainable Circular Economy - Envisioning a Smartphone Firm of the Future
Authors: Junge Ines P. 
Published: August 2023

AbstractThe smartphone industry is undergoing a slow transition towards sustainable design and circular business models in response to mounting social and ecological concerns. This paper discusses a smartphone concept regarding sustainable value creation over its entire lifecycle—thereby urging the creation of alternative designs and future-fit businesses. Hence, drawing inspiration from existing start-ups seeking to establish a sustainable smartphone market, a speculative business proposal is synthesised. It employs an analytical framework, with the three layers ‘agent-situation’, ‘product system’, and ‘business/venture’, custom-made to explore value creation in smartphone design, production, and consumption for both existing businesses and this study’s case. Through the simultaneous consideration of designing and business modelling, this case exemplifies a sensible navigation between sustainability values, regardless of whether trade-offs or even synergies emerge. The resulting cross-fertilisation of the two fields contributes to stretching notions of what is possible and desirable in an advanced circular society future.
Storying the earth: decolonising literacy education through the pedagogical imagination
Authors: McKnight Lucinda 
Published: August 2023

AbstractThis article engages speculatively with Rachel Tonkin’s award-winning work of children’s literary non-fiction Leaf litter: Exploring the mysteries of a hidden world as a potential text for study in the primary or secondary literacy/English classroom. It considers the affordances and issues that may accompany teaching this text, and the pedagogical moves that might make it useful in contemporary times and in pursuit of racial and planetary justice. This work foregrounds the role of the pedagogical imagination in curriculum design, in anticipating how teachers, students and texts perform in the classroom. A more inclusive pedagogical imagination might be pursued, not through reliance on white, Western epistemologies, but through a First Nations First dialogic approach that recognises the intimate entanglements of human and other bodies and matter. This also includes identifying the ubiquity of the white “we”, a coercive pronoun that literacy classrooms can challenge.
Herbicide 2,4-dichlorophenoxyacetic acid interferes with MAP kinase signaling in Fusarium graminearum and is inhibitory to fungal growth and pathogenesis
Authors: Duan Kaili , Shen Qifang , Wang Yu , Xiang Ping , Shi Yutong , Yang Chenfei , Jiang Cong , Wang Guanghui , Xu Jin-Rong , Zhang Xue 
Published: August 2023

AbstractPlant hormones are important for regulating growth, development, and plant-pathogen interactions. Some of them are inhibitory to growth of fungal pathogens but the underlying mechanism is not clear. In this study, we found that hyphal growth of Fusarium graminearum was significantly reduced by high concentrations of IAA and its metabolically stable analogue 2,4-dichlorophenoxyacetic acid (2,4-D). Besides inhibitory effects on growth rate, treatments with 2,4-D also caused significant reduction in conidiation, conidium germination, and germ tube growth. Treatments with 2,4-D had no obvious effect on sexual reproduction but significantly reduced TRI gene expression, toxisome formation, and DON production. More importantly, treatments with 2,4-D were inhibitory to infection structure formation and pathogenesis at concentrations higher than 100 µM. The presence of 1000 µM 2,4-D almost completely inhibited plant infection and invasive growth. In F. graminearum, 2,4-D induced ROS accumulation and FgHog1 activation but reduced the phosphorylation level of Gpmk1 MAP kinase. Metabolomics analysis showed that the accumulation of a number of metabolites such as glycerol and arabitol was increased by 2,4-D treatment in the wild type but not in the Fghog1 mutant. Transformants expressing the dominant active FgPBS2S451D T455D allele were less sensitive to 2,4-D and had elevated levels of intracellular glycerol and arabitol induced by 2,4-D in PH-1. Taken together, our results showed that treatments with 2,4-D interfere with two important MAP kinase pathways and are inhibitory to hyphal growth, DON biosynthesis, and plant infection in F. graminearum.
Electricity consumption characteristics and prediction model of a large airport terminal in Beijing
Authors: Yang Yi , Chen Chao , Li Zhiyong , Guan Dongya , Su Feifei 
Published: August 2023

AbstractThe large airport terminal is the city's transportation hub and logistics center, and its building electricity consumption is twice or even higher than that of general large public buildings. Energy-saving and consumption reduction of the terminal building is not only the need to improve the operational efficiency and reduce the operation cost of the airport but also the need to realize the goal of "double carbon" in China. In this study, a large airport terminal in Beijing is taken as the research object. According to the characteristics of its main electrical equipment system, and the measured data of passenger flow from January 2020 to February 2023, combined with Pearson correlation analysis, K-means cluster analysis and multiple regression analysis, the influence and correlation characteristics of building scale, passenger flow and outdoor meteorological parameters on its electricity consumption are analyzed. The results show that: 1) The daily electricity consumption of the terminal can be analyzed by five levels according to the daily passenger flow, namely, 10,000 < N ≤ 30,000,30,000 < N ≤ 50,000, 50,000 < N ≤ 70,000, 70,000 < N ≤ 100,000, and 100,000 < N ≤ 130,000; 2) The electricity consumption of the terminal can be divided into three categories: basic electricity consumption related to the building scale of the terminal, variable electricity consumption I related to passenger flow, and variable electricity consumption II related to outdoor air temperature and passenger flow. Based on this, the terminal's daily electricity consumption prediction model is constructed, and the measured data verify the model's effectiveness. 3) Put forward the evaluation reference value of the daily electricity consumption of different passenger flow in this terminal, When the year passenger flow reaches the design value of 45 million, the normal daily electricity consumption level ranges from 0.44 to 0.48 kW·h/(m2·day). The research results can provide methods and evaluation reference for electricity consumption prediction, and accurate control of electricity consumption of main equipment systems in airport terminal.
A critical issue: assessing the critical thinking skills and dispositions of undergraduate health science students
Authors: Dissen Anthony 
Published: August 2023

AbstractCritical thinking skills and dispositions are significantly important factors that aid in one’s ability to understand and solve complex problems. Within the field of higher education, critical thinking skills and dispositions are valued and encouraged but are not always fully developed at the completion of the undergraduate degree experience. Those students who are studying to enter the healthcare field are particularly in need of strong critical thinking skills and dispositions in order to provide patients and communities with effective, evidence-based care in the midst of an ever-increasingly complex environment. What program of study a student selects, and the unique curriculum design of that program, may impact the development of these skills and dispositions during undergraduate study. This quantitative study sought to explore and understand the critical thinking skills and dispositions of undergraduate students enrolled in a BS in Health Science (BSHS) degree program, and how these skills in particular compared to the national student population. During the Spring 2022 academic semester, 140 senior-level BSHS students were given the opportunity to complete the California Critical Thinking Skills Test and the California Critical Thinking Disposition Inventory. Results show less development in critical thinking skills when compared to the national student population, with Numeracy skills being the most poorly developed, and Truth-Seeking being the most inconsistent disposition possessed by the student participants. The implications of these findings, particularly for faculty who teach students planning to enter the healthcare field, are offered, including recommendations for curricular design and modification.
Indigenous Archaeologies, Shell Heaps, and Climate Change
Authors: Newsom Bonnie , Soctomah Donald , Blackwood Emily , Brough Jason 
Published: August 2023

ABSTRACTIndigenous communities globally are challenged by threats to heritage resources due to residual effects of colonization, outsider encroachment on traditional spaces, and economic and political inequities. The effects of climate change add another dimension to these challenges, not only by altering familiar ecosystems and landscapes but also through the destruction of Indigenous heritage spaces. The University of Maine's Northeast archaeology program supports Indigenous resilience to climate change through community-engaged approaches to archaeological research. Recent shell heap research at the Holmes Point West site in Machiasport, Maine, exemplifies these efforts by blending archaeological science with service through Passamaquoddy language preservation and community engagement. This article discusses the University of Maine's partnership with the Passamaquoddy Nation and reflects on the nexus of Indigenous archaeology, heritage protection, and climate change resilience.
High-power free-running single-longitudinal-mode diamond Raman laser enabled by suppressing parasitic stimulated Brillouin scattering
Authors: Liu Yuxuan , Zhu Chengjie , Sun Yuxiang , Mildren Richard P. , Bai Zhenxu , Zhang Baitao , Chen Weibiao , Chen Dijun , Li Muye , Yang Xuezong , Feng Yan 
Published: August 2023

Abstract
A continuous-wave (CW) single-longitudinal-mode (SLM) Raman laser at 1240 nm with power of up to 20.6 W was demonstrated in a free-running diamond Raman oscillator without any axial-mode selection elements. The SLM operation was achieved due to the spatial-hole-burning free nature of Raman gain and was maintained at the highest available pump power by suppressing the parasitic stimulated Brillouin scattering (SBS). A folded-cavity design was employed for reducing the perturbing effect of resonances at the pump frequency. At a pump power of 69 W, the maximum Stokes output reached 20.6 W, corresponding to a 30% optical-to-optical conversion efficiency from 1064 to 1240 nm. The result shows that parasitic SBS is the main physical process disturbing the SLM operation of Raman oscillator at higher power. In addition, for the first time, the spectral linewidth of a CW SLM diamond Raman laser was resolved using the long-delayed self-heterodyne interferometric method, which is 105 kHz at 20 W.
On the micelle formation of DNAJB6b
Authors: Carlsson Andreas , Olsson Ulf , Linse Sara 
Published: August 2023

Abstract
The human chaperone DNAJB6b increases the solubility of proteins involved in protein aggregation diseases and suppresses the nucleation of amyloid structures. Due to such favourable properties, DNAJB6b has gained increasing attention over the past decade. The understanding of how DNAJB6b operates on a molecular level may aid the design of inhibitors against amyloid formation. In this work, fundamental aspects of DNAJB6b self-assembly have been examined, providing a basis for future experimental designs and conclusions. The results imply the formation of large chaperone clusters in a concentration-dependent manner. Microfluidic diffusional sizing (MDS) was used to evaluate how DNAJB6b average hydrodynamic radius varies with concentration. We found that, in 20 mM sodium phosphate buffer, 0.2 mM EDTA, at pH 8.0 and room temperature, DNAJB6b displays a micellar behaviour, with a critical micelle concentration (CMC) of around 120 nM. The average hydrodynamic radius appears to be concentration independent between ∼10 μM and 100 μM, with a mean radius of about 12 nm. The CMC found by MDS is supported by native agarose gel electrophoresis and the size distribution appears bimodal in the DNAJB6b concentration range ∼100 nM to 4 μM.
THE PROGRESS OF 14C-AMS ANALYSIS FOR ULTRA-SMALL SAMPLES AT XI’AN AMS CENTER
Authors: Du Hua , Fu Yunchong , Cheng Peng , Zhao Haiyan , Hou Yaoyao , Xiong Xiaohu , Gu Huachun , Yang Ling 
Published: August 2023

ABSTRACTAs there exists a growing demand for chronological research and tracer applications using radiocarbon (14C) analyses of samples smaller than 100 μg C, a compact micro-specific hydrogen graphitization method has been developed at the Xi’an Accelerator Mass Spectrometry (AMS) Center. This article describes the performance of the system and the mass of carbon background produced during ultra-small sample preparation. Furthermore, we discuss the results of contamination corrections and perform 14C analyses on small samples with known age or reference values. The results reveal that our 14C analysis of ultra-small samples of 10–100 μg C can obtain accurate and reliable results, and the micro-scale 14C-AMS analysis technique meets our research objectives for dating and tracer applications.
Effectiveness of the sternocleidomastoid muscle contraction asymmetry and filter: cervical vestibular evoked myogenic potential
Authors: Hançer Arslan G , Arslan M , Aran O T , Özberk E H , Baydan Aran M 
Published: August 2023

AbstractObjectiveThis study aimed to determine the precautions that can be taken to increase the reliability of the vestibular evoked myogenic potentials test without being affected by the asymmetry of the sternocleidomastoid muscle and the issues that should be considered in the interpretation of vestibular evoked myogenic potential results if these precautions are not taken.MethodIndividuals with sternocleidomastoid muscle activity of less than 30 μV in cervical vestibular evoked myogenic potential testing and an asymmetry ratio of more than 0.35 were excluded. In our study, individuals were divided into different groups according to sternocleidomastoid muscle asymetry.ResultsA total of 53 individuals were included in the study. Intergroup comparisons were made to determine the effect of electromyogram scaling and filter use on amplitude asymmetry ratio according to sternocleidomastoid muscle asymmetry.ConclusionKeeping the sternocleidomastoid muscle asymmetry not exceeding 10 μV maximises the reliability of cervical vestibular evoked myogenic potentials. As a result of our study, it can be concluded that in clinical applications the asymmetry should not exceed 20 μV.
HTA capacity building in Asia: towards one goal
Authors: Mundy Linda , Maddern Guy 
Published: August 2023

Abstract

Objectives
The aim of the 2022 Health Technology Assessment International (HTAi) Asia Policy Forum (APF) was to discuss experiences and challenges around health technology assessment (HTA) capacity building for both HTA agencies and companies in the Asia region and to identify possible solutions as part of a capacity building roadmap.

Methods
Discussions during the 2022 APF, informed by a pre-meeting survey of HTA agencies and industry attendees from the region, form the basis of this paper.

Results
HTA is an essential element of priority-setting in healthcare; however, the scarcity of skilled technical HTA practitioners is a rate-limiting step in the conduct of HTA. The lack of investment in HTA and the political will to mandate the use of HTA in decision-making may be due to a lack of understanding of the value of the HTA process, and how HTA is interpreted and used in the healthcare decision-making process.

Conclusions
Increased demand for HTA is created when the value of HTA is recognized. HTA capacity-building challenges may be mitigated by educating stakeholders, particularly policymakers, on the value of, and the need to invest in, HTA as a transparent process to ensure equitable access to health care for all. Investigating a means of funding and implementing an HTA intern program between agencies, in partnership with industry, to facilitate a supportive environment to foster HTA skills and knowledge, build capacity or strengthen existing capacity should be a priority.
Letters to the Paulaharjus from Ruija: The emergence of two writing cultures in Finnish among Kvens in the early twentieth century
Authors: Haataja Daniel , Niiranen Leena 
Published: August 2023

AbstractSamuli Paulaharju was a Finnish ethnographer who visited the Kven minority in Northern Norway – Ruija – in the 1920s and 1930s. Together with his wife Jenny he collected ethnographic material among the Kvens, and corresponded frequently with some of them. Many wrote in Finnish, and most were self-taught writers.We focus on the orthography used by these writers who were writing in a multilingual environment. We identify two writing cultures, one associated with Old Literary Finnish and Early Modern Finnish, the other with Modern Written Finnish (MWF). The orthography used by the former is characterized by the use ofb,d,gforp,t,kin native Finnish words, which we attribute to influence from Norwegian. By contrast, the orthography of the latter largely resembles the MWF of the time. However, both groups substitutetford– a phenomenon found in Finland during the same time period – as well as occasionally use Norwegian characters.
The European Commission's Glass Fibre Fabrics Investigation and the Boundaries Between Investment and Trade
Authors: AHMAD Zaker 
Published: August 2023

AbstractIn a 2020 anti-subsidy investigation concerning glass fibre fabric (GFF) products from Egypt, the European Commission (EC) attributed the Chinese government's conduct to the government of Egypt in a way that raised a systemic question about the boundary between trade and investment. This article argues that despite some overlap between the boundaries of these legal disciplines, the notions of trade and investment remain conceptually distinct. Customary rules of interpretation dictate that World Trade Organization (WTO) covered agreements are construed as facilitating trade relations and no further. Hence, an extension of WTO subsidy rules to cover outward investment promotion measures using the principles of state responsibility is untenable. Such a unilateral approach disproportionately affects the interests of developing countries, harming their efforts to draw green investments. This article recommends that new, balanced rules be designed to promote outward investments while limiting adverse trade impacts.
Drivers of Surface Ocean Acidity Extremes in an Earth System Model
Authors: Burger Friedrich A. , Frölicher Thomas L. 
Published: August 2023

AbstractOceanic uptake of anthropogenic carbon causes acidification, a process that describes the increase in hydrogen ion concentrations ([H+]) and decrease in calcium carbonate mineral saturation states (Ω). Of particular concern are ocean acidity extreme (OAX) events, which pose a significant threat to many calcifying marine organisms. However, the mechanisms driving such extreme events are not well understood. Here, we use high‐frequency output from a fully coupled Earth system model of all processes that influence the surface ocean temperature and carbon budgets and ultimately [H+] and Ω anomalies to quantify the driving mechanisms of the onset and decline of high [H+] and low Ω extreme events. We show that enhanced temperature plays a crucial role in driving [H+] extremes, with increased net ocean heat uptake being the dominant driver of the event onset in the subtropics. In the mid‐to‐high latitudes, decreased downward vertical diffusion and mixing of warm surface waters during summer, and increased vertical mixing with warm and carbon‐rich subsurface waters during winter are the main drivers of high [H+] extreme event onset. In the tropics, increases in vertical advection of carbon‐rich subsurface waters are the primary driver of the onset of high [H+] extremes. In contrast, low Ω extremes are driven in most regions by increases in surface carbon concentration due to increased vertical mixing with carbon‐rich subsurface waters. Our study highlights the complex interplay between heat and carbon anomalies driving OAX events and provides a first foundation for more accurate prediction of their future evolution.
Ferroptosis and pyroptosis signatures in critical COVID-19 patients
Authors: Peleman Cédric , Van Coillie Samya , Ligthart Symen , Choi Sze Men , De Waele Jan , Depuydt Pieter , Benoit Dominique , Schaubroeck Hannah , Francque Sven M. , Dams Karolien , Jacobs Rita , Robert Dominique , Roelandt Ria , Seurinck Ruth , Saeys Yvan , Rajapurkar Mohan , Jorens Philippe G. , Hoste Eric , Vanden Berghe Tom 
Published: August 2023

AbstractCritical COVID-19 patients admitted to the intensive care unit (ICU) frequently suffer from severe multiple organ dysfunction with underlying widespread cell death. Ferroptosis and pyroptosis are two detrimental forms of regulated cell death that could constitute new therapeutic targets. We enrolled 120 critical COVID-19 patients in a two-center prospective cohort study to monitor systemic markers of ferroptosis, iron dyshomeostasis, pyroptosis, pneumocyte cell death and cell damage on the first three consecutive days after ICU admission. Plasma of 20 post-operative ICU patients (PO) and 39 healthy controls (HC) without organ failure served as controls. Subsets of COVID-19 patients displayed increases in individual biomarkers compared to controls. Unsupervised clustering was used to discern latent clusters of COVID-19 patients based on biomarker profiles. Pyroptosis-related interleukin-18 accompanied by high pneumocyte cell death was independently associated with higher odds at mechanical ventilation, while the subgroup with high interleuking-1 beta (but limited pneumocyte cell death) displayed reduced odds at mechanical ventilation and lower mortality hazard. Meanwhile, iron dyshomeostasis with a tendency towards higher ferroptosis marker malondialdehyde had no association with outcome, except for the small subset of patients with very high catalytic iron independently associated with reduced survival. Forty percent of patients did not have a clear signature of the cell death mechanisms studied in this cohort. Moreover, repeated moderate levels of soluble receptor of advanced glycation end products and growth differentiation factor 15 during the first three days after ICU admission are independently associated with adverse clinical outcome compared to sustained lower levels. Altogether, the data point towards distinct subgroups in this cohort of critical COVID-19 patients with different systemic signatures of pyroptosis, iron dyshomeostasis, ferroptosis or pneumocyte cell death markers that have different outcomes in ICU. The distinct groups may allow ‘personalized’ treatment allocation in critical COVID-19 based on systemic biomarker profiles.