bluuebunny/crossref_metadata_2025_split huggingface dataset:
The reintroduction project ofCypripedium calceolusin Switzerland
Authors: Sprunger Samuel , de Jong Camiel 
Published: April 2023

SummaryIn 2013, a project to reintroduceCypripedium calceolusin the Swiss Jura was organised between the Swiss Orchid Foundation at the Herbarium of JanyRenz, Basel, Switzerlandand Anthura B.V., Bleiswijk, Holland with the approval of the Nature Conservation authorities of nine cantons in the Swiss Jura. Seed was legally collected from sites in the nine cantons and was successfully grown to flowering size by the commercial nursery in the Netherlands. Three thousand flowering sized plants were successfully reintroduced to 43 sites in the summer of 2018. Monitoring in successive years has shown a success rate of over 50% and much higher in some sites. The successful collaboration of conservation authorities, a charitable foundation (Swiss Orchid Foundation) and a commercial company (Anthura B.V.) in the conservation of an endangered plant might serve as a model of how other projects might be run. A version of this paper, in German may be found inBauhinia.
Comparison of brief group behavioural parent training with individual parent training for preschool children with attention deficit hyperactivity disorder: A randomized feasibility study
Authors: Vaidyanathan Sivapriya , Chandrasekaran Venkatesh , Kandasamy Preeti 
Published: April 2023

AbstractBackgroundBehaviour parent training (BPT) is first‐line treatment for preschool attention deficit hyperactivity disorder (ADHD). BPT in a group format can be a cost‐ and time‐effective alternative in low and middle‐income countries (LMIC) settings with limited resources. We conducted a randomized controlled trial to compare the feasibility and efficacy of group BPT with individual BPT in improving ADHD severity in the preschool age group over 12 weeks.MethodsAfter approval by the ethical committee, the study was conducted in the child guidance clinic, JIPMER. Fifty‐six children aged 2.5 to 6 years diagnosed with ADHD according to DSM5 were recruited. Children with autism spectrum disorder and a social quotient less than 50 were excluded. Block randomization parallel design was done. Group interventions were delivered with 4–8 parents per group, focusing on psychoeducation, structuring of routine, attention enhancing tasks, behavioural parenting techniques, and TAU. ADHD severity was assessed using Conner's abbreviated behaviour rating scale at baseline, 4, 8, and 12 weeks. Parental stress was estimated by FISC‐MR adapted for ADHD. Statistical analysis included repeated measures ANOVA.ResultsSignificant improvement was noticed for both groups (F = 20.261, p < .001, ES (η2) = 0.539). Group intervention was not inferior to individual BPT in reducing ADHD severity (F = 0.860, p = .468, ES (η2) = 0.047). There was a statistically significant difference from baseline to 12 weeks of intervention in the reduction of parental stress (F = 20.80, p < .001, ES (η2) = 0.278) and enhancement of the coping strategies (F = 64.4, (p < .001), ES (η2) = 0.78). The intervention had high attendance and fidelity rates.ConclusionGroup BPT was promising in treating ADHD in low‐resource settings.
Fish functional gradients along a reservoir cascade
Authors: Besson Jordan C. , Neary Joshua J. , Stafford Joshua D. , Dunn Corey G. , Miranda Leandro E. 
Published: April 2023

Abstract

The transformations of fish assemblages caused by reservoir cascades can be severe at the reach scale, but basin‐scale effects are less clear. However, prevailing river concepts provide a framework for predicting basin‐scale effects.

To determine if predictions made by the River Continuum Concept relative to the function of fish assemblages are sustained in a temperate river transformed into a reservoir cascade, we examined longitudinal trends in the distribution of fish functional traits over 23 reservoirs of the Tennessee River, U.S.A.

In all, 115 species were recorded representing 62 traits, with trait richness increasing longitudinally in a downstream direction. Trophic, reproductive, and habitat traits showed various increasing and decreasing patterns up and down the reservoir cascade. The observed gradients in trait richness and trait distributions were generally consistent with those expected in unregulated rivers, with few unexpected results.

The transformation of lotic systems into lentic ones has changed habitats and sources of food and encouraged the proliferation of certain feeding (e.g., detritivores, planktivores, invertivores, piscivores), reproduction (e.g., nest spawners polyphils, broadcast spawners phytolithophils), and habitat (slow current, lacustrine, large river) traits. In essence, reservoirs have expanded downstream habitats in an upstream direction, and thus allowed upstream expansion of species and traits that would have normally not been well represented in upper reaches of the Tennessee River basin. Nevertheless, the impounded Tennessee River has maintained much of its functional integrity, despite extensive alterations to the riverscape.

We suggest that, while reservoirs have been shown to have major local‐scale effects on riverine fish assemblages, with access to riverine habitats, and with proactive conservation strategies, fish functional richness can remain remarkably high at the basin scale.
Main ecological and environmental factors affecting forage yield and quality in alpine summer pastures (NW‐Italy, Gran Paradiso National Park)
Authors: Mainetti Andrea , Ravetto Enri Simone , Pittarello Marco , Lombardi Giampiero , Lonati Michele 
Published: April 2023

AbstractSummer pastures in the European Alps play a crucial role in providing high quality forage for grazing livestock and encompass a wide variety of vegetation communities. The main issue of their management is the optimal exploitation of the available forage in relation to environmental constraints, aiming at obtaining the highest forage yield and quality from each vegetation community. In this work, we monitored six different vegetation communities characterized by contrasting topographic features and species compositions throughout the grazing season for two years. We performed botanical and phenological surveys, climate‐related measurements, and herbage samplings to assess forage quantity and quality (i.e., digestibility and proximate composition, estimated by near‐infrared reflectance spectroscopy). We analysed the influence of climatic, topographic, and vegetation variables on pasture herbage through univariate and multivariate analyses. The cover of wide‐leaf grasses primarily promoted biomass production, which was in turn lowered by increasing elevation and slope. On the other hand, a minor effect on forage yield was observed for an increasing cover of sedges and rushes and mean temperatures. Climatic variables (especially water deficit) and advanced phenological stages were the main degrading factors of forage quality in terms of crude protein and digestibility, while enhancing fibre contents. At increasing cover of legumes, fibre content declined and digestibility increased consequently, while the abundance of other non‐legume forbs played a significant role in lowering fibre content. Multivariate analysis highlighted the differing influence of single plant species on forage features even within the same functional species pool. However, attention should be paid to the toxicity and low palatability of some plants, especially forbs. Eutrophic vegetation communities, rich in wide‐leaf grasses and legumes, could be maintained and enhanced through pastoral management to increase alpine pasture production and quality.
In‐hospital nursing care intervention increasing the effect of vacuum sealing drainage on wound healing: A meta‐analysis
Authors: Yu Lan , Wang Yiling , Ma Dongmei , Pan Liming , Liu Xinyang , Chu Tianyue , Yin Baoyue , Huang Lei , Xu Xin 
Published: April 2023

AbstractVacuum sealing drainage (VSD) could effectively drain superficial wounds and deep tissues, which is beneficial for wound healing. More incentives in nursing care to improve the therapeutic effect of VSD on wound healing were further investigated. Different databases were retrieved for full‐text publications about the comparison between intervention nursing care and regular nursing care. Heterogeneity was detected by I2 method, and a random‐effect model was applied for data pooling if there existed heterogeneity. Publication bias was analysed by a funnel plot. Eight studies with 762 patients were included for final meta‐analysis. In the nursing care intervention group, shorter hospital stay duration (pooled SMD = −2.602, 95% confidence interval: −4.052–−1.151), shorter wound healing time (pooled SMD = −1.105, 95% confidence interval: −1.857–−0.353), lower pain score (pooled SMD = −2.490, 95% confidence interval: −3.521–−1.458), lower drainage tube blocked rate (pooled RR = 0.361, 95% confidence interval: 0.268–0.486), and higher nursing satisfaction (pooled RR = 1.164, 95% confidence interval: 1.095–1.237) was confirmed. More active and incentive nursing care could significantly improve the therapeutic effect of VSD on wound healing, in terms of hospitalisation time, wound healing time, painful symptoms, drainage tube blockage, and nursing satisfaction.
Primary Carcinoma of Lung Associated with Primary Malignancies in Other Systems
Authors: Sochocky S. 
Published: April 2023

The aim of this study was to determine the frequency and association of primary carcinoma of the lung with primary malignancies in other systems of the body.Among 237,963 patients, 2,095 had primary carcinoma of lung. Among this group of 2,095 patients with primary carcinoma of lung 180 had one or more second primary malignancies in other systems of the body.
The relationship between peer bullying, loneliness, and social support in refugee adolescents
Authors: Karakus Ozlem , Altinel Busra , Kocak Uyaroglu Arzu 
Published: April 2023

AbstractProblemThis study was conducted to investigate the relationship between peer bullying, loneliness and perceived social support in refugee adolescents.MethodsThis research was conducted with 514 refugee adolescents living in the Central Anatolia region of Turkey. In this descriptive correlational study, data were collected using the Peer Bullying Scale Adolescent Form, the Loneliness Scale, and the Multidimensional Scale of Perceived Social Support.FindingsThe mean score of the refugee adolescents on the victim subscale of the Peer Bullying Scale was 86.71 ± 27.51, and on the bully subscale was 68.08 ± 16.41. The mean score of the adolescents on the Loneliness Scale was 49.63 ± 9.50, on the Perceived Social Support was 52.19 ± 1.66. A positive moderate relationship was observed between the bully subscale and the victim subscale of the Peer Bullying Scale (p < 0.05). No relationship was found between the bully and victim subscales of the Peer Bullying Scale and the scores for the Loneliness Scale and the Perceived Social Support (p > 0.05). The male refugee youth were found to have higher mean victim and bully scores than the female refugee youth.ConclusionIn light of these results, the reasons for the peer bullying of refugee adolescents should be investigated and solutions should be developed based on the reasons. It is recommended to conduct quantitative and qualitative research aimed at revealing the reasons why refugee adolescents may engage in bullying and be exposed to bullying in the future.
Cutaneous manifestations induced by check point inhibitors in 120 melanoma patients—The European MelSkinTox study
Authors: L'Orphelin J.‐M. , Cassecuel J. , Kandolf L. , Harwood C. A. , Tookey P. , Junejo M. H. , Hogan S. , Lebbé C. , Appalla Z. , Kränke T.‐M. , Pellacani G. , Cerasuolo D. , Dujovic B. , Del Marmol V. , Forschner A. , Garbe C. , Bataille V. , Ressler J. M. , Sollena P. , Dompmartin A. , Peris K. , Dreno B. ,   And European Association of Dermato‐Oncology
Published: April 2023

AbstractBackgroundCheckpoint inhibitors provide an effective approach for the melanoma treatment. They prolong lymphocyte effects, which explains the cytotoxicity underlying immune‐related adverse events (IrAEs). Cutaneous IrAEs affect nearly 40% of PD‐1i and 50% of CTLA4i‐treated patients. Severe cutaneous irAE do not often occur but could be life‐threatening and may persist despite treatment discontinuation.MethodsWe aimed to investigate cutaneous IrAEs in a cohort of patients treated with ICI across Europe in an effort to characterize the reactions in a real‐world, phase IV, post‐marketing study using a follow‐up questionnaire.Data since November 2016 until March 2021 were obtained from the Melskintox database, a European multicentric biobank dedicated to the follow‐up of melanoma and cutaneous adverse events, supported by EADO. The dermatoses reported were pooled into four categories: inflammatory dermatosis, bullous diseases, drug‐related eruptions and pigmentary diseases.ResultsInflammatory benign dermatoses (n = 63) represented the most common group of reactions (52.5%), followed by drug‐related eruptions (n = 24, 20%), pigmentary diseases (n = 23, 19.2%) and bullous diseases (n = 10, 8.3%). Grade II (n = 41, 34.2%) are represented by bullous pemphigoid, eczema, hypodermitis, lichenoid eruption, maculopapular rash, pruritus, psoriasis‐like rash, urticarial eruption and vitiligo. Grade III (n = 18, 15.0%) are represented by bullous pemphigoid, lichenoid eruption and rashes. Grade IV (n = 2, 1.7%) is only represented by bullous disease. Most cutaneous IrAEs led to immunotherapy continuation (n = 95, 88.0%). CR is associated with more severe the cutaneous irAEs. We report an average time‐to‐onset of 208 days and some late‐onset events.ConclusionOur study has characterized the clinical spectrum of cutaneous irAEs, their timing and severity and their relationship with tumour response. Grade I–II cutaneous IrAE are easily managed allowing ongoing anticancer treatment. Severe late‐onset cutaneous irAE are not uncommon. A dermatological follow‐up helps mitigate the risk of life‐threatening adverse events. These findings highlight the importance of oncodermatological involvement in management of patients with melanoma receiving immunotherapy.
Discipline and resistance in southwestern Ontario: Securitization of migrant workers and their acts of defiance
Authors: Ramsaroop Chris 
Published: April 2023

AbstractCOVID‐19 has had deep impacts on a wide range of vulnerable communities in Canada. Migrant agricultural workers in the southwestern region of Ontario were particularly impacted. Fearing the threat of the ‘racialized foreign other’, the Canadian state produced myriad securitization responses with heightened surveillance. This paper will examine both state and non‐state forms of securitization and the response from both workers and activists such as the advocacy group Justicia for Migrant Workers (J4MW). While there has been ample discussion of how vulnerable migrant agricultural workers were affected during the pandemic, there has been less attention paid to how state policies have heightened and targeted specific groups such as migrant agricultural workers through modes of securitization. Central to this was to ensure that labour needs would be met to ensure the viability of Canada's multi‐billion agricultural industry. This paper shows how securitization and control were vital to ensure no disruptions to production levels and Canada's role as a leading agricultural export producer.
Post‐rhinoplasty complications with previous hyaluronic acid injection history: Cerebral infarction and vision loss
Authors: Yu Boya , Zhou Guiwen , Fu Qiang , Yang Yi , Li Shiyi , Zheng Can , Chen Minliang 
Published: April 2023

AbstractBackgroundRhinoplasty is becoming increasingly frequent as the pursuit of aesthetics by people accelerates. In recent years, the proportion of people opting for rhinoplasty injections has gradually increased. This has led to numerous reports citing catastrophic postoperative complications such as skin necrosis, cerebral infarction, and visual impairment.AimThe aim of our report is to discuss the possible etiological factors for this post‐rhinoplasty complication and provides a rationale for HA injection history as a risk factor in rhinoplasty.MethodsWe report a rare case that received nasal HA injections in the past without any untoward incident. She opted for a second rhinoplasty 2 years after her initial nasal HA injections. This second intervention led to post‐injection loss of vision in one eye and cerebral infarction. Following clinical and radiological examination, digital subtraction angiography (DSA) and superselective intra‐arterial thrombolysis were performed.ResultsThe patient did not develop disuse exotropia or ocular atrophy, but the left eye remained without light perception, which implies that intra‐arterial thrombolytic therapy may be a positive and effective method to maintain the normal appearance of the eye.ConclusionIt is advisable for patient safety to maintain a long interval of time between hyaluronidase injection and repeat rhinoplasty. Clinicians should become familiar with the anatomical peculiarities of the patient and be gentle during the rhinoplasty procedure.
Evaluation of the effect of3D‐bioprinted gingival fibroblast‐encapsulatedADMscaffolds on keratinized gingival augmentation
Authors: Liu Peng , Li Qing , Yang Qiaolin , Zhang Shihan , Yi Ke , Zhang Guifeng , Tang Zhihui 
Published: April 2023

AbstractBackground and ObjectivesThe keratinized gingiva plays an important role in maintaining healthy periodontal and peri‐implant tissue. Acellular dermal matrix (ADM), as a substitute biomaterial, has a porous structure and good biocompatibility. 3D‐bioprinting has the potential for tissue engineering because it enables precise loading of cells layer‐by‐layer. Herein, we bioprinted ADM scaffold encapsulating gingival fibroblasts (GFs) and evaluated its efficacy in keratinized gingiva augmentation in vivo to assess its potential for clinical periodontal tissue regeneration.MethodsGFs were extracted from the gingiva of beagles and transfected with a green fluorescent protein (GFP). The ADM scaffold (ADM cell‐free group) was constructed using ADM, gelatin, and sodium alginate mixed at an appropriate ratio via 3D‐bioprinting. The ADM cell scaffold (ADM cell group) was established by adding extra GFs in the same manner. Six beagles were divided into blank control, ADM cell‐free, and ADM cell groups; and implant surgery was performed. The keratinized gingiva was clinically and histologically evaluated at baseline and after 2 months.ResultsGFs transfected with GFPs expressed green fluorescence and were present in new tissue in the ADM cell group and not observed in the ADM cell‐free group. At 2 months after surgery, the keratinized gingival augmentation in the ADM cell group was significantly more than that in the ADM cell‐free group. Attached gingival augmentation was also observed more in the ADM cell group than that in the ADM cell‐free group. Histological staining showed that the tissue in the ADM cell group displayed a more integrated structure and higher expression of COL I, COL III, and VEGF‐A than those in the ADM cell‐free group.Conclusion3D‐bioprinted GF‐encapsulated ADM scaffolds increased the amount of keratinized gingiva in vivo, suggesting that 3D‐bioprinting has great potential for oral soft tissue regeneration.
Disparities in telehealth access, not willingness to use services, likely explain rural telehealth disparities
Authors: Ko Jamie S. , El‐Toukhy Sherine , Quintero Stephanie M. , Wilkerson Miciah J. , Nápoles Anna M. , Stewart Anita L. , Strassle Paula D. 
Published: April 2023

AbstractPurposeAlthough telehealth access and utilization have increased during the pandemic, rural and low‐income disparities persist. We sought to assess whether access or willingness to use telehealth differed between rural and non‐rural and low‐income and non‐low‐income adults and measure the prevalence of perceived barriers.MethodsWe conducted a cross‐sectional study using COVID‐19's Unequal Racial Burden (CURB) online survey (December 17, 2020‐February 17, 2021), which included 2 nationally representative cohorts of rural and low‐income Black/African American, Latino, and White adults. Non‐rural and non‐low‐income participants from the main, nationally representative sample were matched for rural versus non‐rural and low‐income versus non‐low‐income comparisons. We measured perceived telehealth access, willingness to use telehealth, and perceived telehealth barriers.FindingsRural (38.6% vs 44.9%) and low‐income adults (42.0% vs 47.4%) were less likely to report telehealth access, compared to non‐rural and non‐low‐income counterparts. After adjustment, rural adults were still less likely to report telehealth access (adjusted prevalence ratio [aPR] = 0.89, 95% CI = 0.79‐0.99); no differences were seen between low‐income and non‐low‐income adults (aPR = 1.02, 95% CI = 0.88‐1.17). The majority of adults reported willingness to use telehealth (rural = 78.4%; low‐income = 79.0%), with no differences between rural and non‐rural (aPR = 0.99, 95% CI = 0.92‐1.08) or low‐income versus non‐low‐income (aPR = 1.01, 95% CI = 0.91‐1.13). No racial/ethnic differences were observed in willingness to use telehealth. The prevalence of perceived telehealth barriers was low, with the majority reporting no barriers (rural = 57.4%; low‐income = 56.9%).ConclusionsLack of access (and awareness of access) is likely a primary driver of disparities in rural telehealth use. Race/ethnicity was not associated with telehealth willingness, suggesting that equal utilization is possible once granted access.
Simulating policy responses to multiple economic shocks: An experiment with combined impacts of COVID‐19 and oil price crash on Kuwait
Authors: Gelan Ayele U. , Al‐Qudsi Sulayman , AlAwadhi Ahmad 
Published: April 2023

AbstractResearchers and policy‐makers are used to measuring impacts of an economic shock. However, multiple economic shocks generate disruption that are challenging, not just analytically but also in the interpretations of results (Pagan & Robinson, European Economic Review, 145, 2022, 104120). The disruptions come through multiple channels whose impacts were trickier to measure than emanating from those of a single shock. This study develops and applies a framework to conduct simulation experiments with multiple economic shocks. Kuwaiti data were used to simulate multiple economic shocks to the economy originating from the Corona Pandemic and the collapse of oil price, which simultaneously happened during the first quarter of 2020. As an oil exporting country, Kuwait is used to dealing with recurrent changes in oil prices in the world market as a single shock. However, unlike the oil shock, COVID‐19 has many demand and supply shocks, each with separate transmission channels. The objective here is to quantify relative contributions to overall adverse effects on GDP, and then identify policy instruments required to implement a successful recovery. A recursive dynamic economy‐wide model was formulated and calibrated. The results indicate that the GDP effects range from 35% to 11% declines from the baseline scenario depending on effectiveness of policy responses.