bluuebunny/crossref_metadata_2025_split huggingface dataset:
Molecular genetic aspects of adrenocortical cancer
Authors: Yashina D. P. , Afanasyeva Z. A. 
Published: July 2023

Adrenocortical cancer is a rare tumor originating from cortical adrenal cells, endowed with aggressive potential, a rapidly progressing course and an unfavorable prognosis. The complexity of early diagnosis of the disease is due to several factors: the variability of clinical manifestations associated with the initial multiregulatory influence of steroid hormones on the body’s homeostasis, the rare occurrence of the tumor and, as a result, the lack of understanding of the molecular mechanisms of its carcinogenesis.The increased interest in recent years among oncologists and endocrinologists in understanding the fundamental and clinical aspects of adrenocortical cancer and the search for potential targets for new drugs has led to a detailed study of the cellular and molecular genetic mechanisms involved in normal adrenal ontogenesis and their role in tumor transformation. This review presents the currently known molecular genetic processes and their mediating auto-, para-, endocrine factors involved in normal adrenal ontogenesis and carcinogenesis. The paper analyzes results of trials published in international and Russian journals on molecular oncology and endocrinology indexed in the PubMed, CyberLeninka, Web of Science, Science Direct and eLIBRARY databases.
Тайны «перестройки»
Authors: Ильинский Игорь Михайлович 
Published: July 2023

<p>Статья известного социального философа, ректора Московского гуманитарного университета И. М. Ильинского представляет собой вариант текста главы в книге о «перестройке», над которой автор работает уже многие годы. Данный текст продолжает тему предыдущей статьи И. М. Ильинского, опубликованной в журнале «Знание. Понимание. Умение» (2023. № 1). Автор развивает свою аргументацию относительно того, что, согласно представленным им фактам, «перестройка» была именно заговором высших лиц государства против советской общественной и политической системы. Опираясь на исследования советского государственного деятеля Н. И. Рыжкова, автор показывает, что реально «перестройка» началась еще в период правления Ю. А. Андропова (1983), однако радикальный характер она приняла во второй половине 1980-х гг. И, как обосновывается в статье, в своем радикальном варианте «перестройка» воплощала замысел вовсе не к улучшению социализма в СССР, но, напротив, была подчинена задачам разрушения советской «системы». При этом «прорабы» «перестройки» в лице Горбачева, Яковлева и Шеварднадзе опирались в своих намерениях на многочисленный слой советской интеллигенции, при игнорировании реальной воли населения страны, которая была прежде всего выражена на референдуме 1990 г. В то же время, как показывает Ильинский, советский народ не мог выразить более сильного протеста против развала страны, поскольку люди были погружены в повседневные нужды, перегружены политической информацией, подавлены быстротой происходящих изменений и т. д. Однако при всех этих обстоятельствах, как показали социологические исследования, данные которых приводятся в статье, на самом деле население СССР на рубеже 1980–1990-х гг. предпочитало в большинстве своем социализм капитализму.</p>
Антропонимические герои в современном пространстве коммуникации
Authors: Завьялова Наталья Алексеевна 
Published: July 2023

<p>Работа является частью исследовательской программы по изучению особенностей функционирования единиц языка в условиях современной культурной коммуникации. Цель работы — разработка методики изучения прецедентных антропонимов, значимых для массового сознания представителей различных культур и цивилизаций. На материале русского, китайского и английского культурных кодов исследуется антропоним «Карлсон».</p><p> Антропоним описывается с позиции синхронии и диахронии. Важной чертой антропонима является то, что он не потерял своей актуальности для постсоветской России и благополучно мигрировал из советских анекдотов в современную действительность. В статье предпринята попытка уточнить терминологический аппарат, наряду с отечественными терминами приводятся актуальные для международной науки термины на английском языке. Авторами разработана комплексная методика описания антропонима с привлечением материала электронных онлайн-корпусов, системы поиска семантически связанных слов «Серелекс», оценкой качества аудиовизуального перевода.</p><p>Сформированная в ходе исследования модель представляет собой следующие этапы: монолингвальный контент-анализ примеров с антропонимом из лингвистических корпусов, словарей; полилингвальный контрастивный контент-анализ примеров с антропонимом из лингвистических корпусов, словарей; анализ частотности антропонима и семантически близких лексем, их кластеризация в монолингвальном и полилингвальном сопоставительном режиме; антропоним в экстралингвистическом пространстве (описание артефактов, использующих антропоним, транслируемый им образ); степень популярности антропонима в пространстве электронной коммуникации; инварианты перевода антропонима в аудиовизуальной среде; анализ функциональной социолингвистической направленности контекстов с антропонимом; описание функционирования антропонима в синхроническом и диахроническом аспектах.</p><p>Результаты исследования могут найти свое применение в комплексе современных наук, фокус которых направлен на важные особенности и законы электронной коммуникативной среды.</p>
Slip Deficit Rates on Southern Cascadia Faults Resolved with Viscoelastic Earthquake Cycle Modeling of Geodetic Deformation
Authors: Materna Kathryn , Murray Jessica R. , Pollitz Fred , Patton Jason R. 
Published: July 2023

ABSTRACT
The fore-arc of the southern Cascadia subduction zone (CSZ), north of the Mendocino triple junction (MTJ), is home to a network of Quaternary-active crustal faults that accumulate strain due to the interaction of the North American, Juan de Fuca (Gorda), and Pacific plates. These faults, including the Little Salmon and Mad River fault (LSF and MRF) zones, are located near the most populated parts of California’s north coast and show paleoseismic evidence for three slip events of several-meter scale in the past 1700 yr. However, the geodetic slip rates of these faults are poorly constrained. In this work, we analyze a new compilation of interseismic geodetic velocities from Global Navigation Satellite Systems, leveling, and tide gauge data near the MTJ to constrain present-day slip deficit rates on upper-plate faults and coupling on the megathrust. We construct Green’s functions for interseismic slip deficit for discrete faults embedded in an elastic plate overlying a viscoelastic mantle. We then use a constrained least-squares inversion to determine best-fitting slip rates on the major faults and investigate slip rate trade-offs between faults. Results indicate that the LSF and MRF systems together accumulate 4–5 mm/yr of reverse-slip deficit, although their separate slip rates cannot be determined independently. Modeling of the horizontal and vertical velocities suggests that the southernmost CSZ is coupled interseismically to deeper than 25 km depth. We also find that 6–17 mm/yr of right-lateral slip deficit extends north of the MTJ and into the southern Cascadia fore-arc. These results reinforce the notion that both the southernmost Cascadia megathrust and the smaller fore-arc faults above it contribute to regional seismic hazard.
Combining Seismotectonic and Catalog-Based 3D Models for Advanced Smoothed Seismicity Computations
Authors: Pandolfi Claudia , Taroni Matteo , de Nardis Rita , Lavecchia Giusy , Akinci Aybige 
Published: July 2023

Abstract
The new generation seismic hazard maps use 3D seismotectonic fault models, which are more consistent with the actual nature of faults, whereas the classical models based on earthquake catalogs only utilize a 2D representation of the seismicity. Although the former provides more reliable information on seismogenic structures, the latter can deliver trustworthy seismicity rates easily. Therefore, it is necessary to combine both the approaches to create a high-quality seismic hazard assessment model. This study proposes an innovative approach using smoothed seismicity methods that can be advantageous in all contexts with available 3D fault models and high-quality seismic catalogs. We applied our method on the Adriatic Basal Thrust (ABT) in eastern central Italy—a lithospheric-scale active contractional structure with a well-constrained 3D geometric–kinematic reconstruction and a related high-quality catalog. Our new 3D algorithm was applied to smooth the ABT seismicity on the grid, resulting in a 3D earthquake rate model that also provides rupture parameters such as strike, dip, rake, and seismogenic thickness. Our approach is particularly useful for complex seismotectonic settings, such as in cases of lithospheric shear zones, subduction planes, and overlapping multidepth seismogenic volumes.
Comparative study of representatives of different populations of <i>Sedum roseum</i> (L.) Scop growing in conditions of field crop rotation
Authors: Savchenko O. M. , Tsybulko N. S. , Samatadze T. E. 
Published: July 2023

Aim. Comparative study of the source material of four populations of Sedum roseum (L.) Scop. belonging to different ecological and geographical zones of origin and assessment of their suitability for cultivation in the conditions of the non‐chernozem zone of the Russian Federation.Materials and methods. The following populations were studied: the cultivated population of VILAR (Altai, 1980), the cultivated population of the Botanical Garden of Pitirim Sorokin Syktyvkar State University (Syktyvkar, Komi Republic), an introduced population from Kirovsk, N. A. Avrorin Polar‐Alpine Botanical Garden‐Institute and a cultivated population of Innsbruck Botanical Garden, Austria.Results. Morphological description of the samples was carried out and the productivity of raw materials and seeds and the main biological and karyological features of the populations studied were determined. The results of made it possible to identify Rhodiola populations characterized by high winter hardiness (A and D) and low winter hardiness (B and C). A high productivity of roots and rhizomes in the fourth year of life in populations C and A (30–31 g) was established, and in terms of the content of active substances (phenylpropanoids) in population B (Komi) – 5.4%. The numbers of chromosomes (2n=22) were determined and their morphometric analysis was carried out and formulas of karyotypes of the Rhodiola populations studied were compiled. Chromosomal analysis using C/DAPI‐differential staining showed that no chromosomal abnormalities were detected in the karyotypes, which indicates their stability.Conclusion. Morphological variability indicates the ecological plasticity of the populations studied, which indicates the prospects for their field cultivation.
The Gravity Model of Trade: The Case of Central and Eastern Europe
Authors: Lypko Nazarii 
Published: July 2023

The main patterns of international trade in the countries of Central and Eastern Europe have been analysed in the paper. The gravity model, estimated for a large sample of bilateral trade flows for the analysed states, has been used as a benchmark. The model has been updated according to the modern conditions in the international economy. The emphasis has been made on the analysis of products' trade since the trade of services requires separate modelling. The purpose of the paper was to find the main factors that determine gravity trends in international trade in Central and Eastern Europe. It has been proven that the distance between countries and their gross domestic products are still crucial factors which determine trade flows between them. Additionally, the influence of the product structure of export has been considered. A higher share of value-added export increases bilateral trade between the countries. Common past for the analysed countries boosts trade between them because of the presence of historical trade traditions and the development of regional production agglomeration. It has been proven that the gravity equation remains a simple and reliable model of the factors which determine the trade between countries.
Povzetek. V prispevku so analizirani glavni vzorci mednarodne trgovine v državah srednje in vzhodne Evrope. Kot merilo je bil uporabljen gravitacijski model, ocenjen za velik vzorec dvostranskih trgovinskih tokov analiziranih držav. Model je bil posodobljen glede na sodobne razmere v mednarodnem gospodarstvu. Poudarek je bil na analizi trgovine z izdelki, saj trgovina s storitvami zahteva ločeno modeliranje. Namen prispevka je bil ugotoviti glavne dejavnike, ki določajo gravitacijska gibanja v mednarodni trgovini v Srednji in Vzhodni Evropi. Izkazalo se je, da sta razdalja med državami in njihov bruto domači proizvod še vedno ključna dejavnika, ki določata trgovinske tokove med njimi. Poleg tega je bil upoštevan tudi vpliv strukture izdelkov pri izvozu. Večji delež izvoza z dodano vrednostjo povečuje dvostransko trgovino med državami. Skupna preteklost analiziranih držav spodbuja trgovino med njimi zaradi prisotnosti zgodovinskih trgovinskih tradicij in razvoja regionalnih proizvodnih aglomeracij. Dokazano je bilo, da gravitacijska enačba ostaja preprost in zanesljiv model dejavnikov, ki določajo trgovino med državami.
Tibial Tubercle Osteotomy in Revision Total Knee Arthroplasty for Periprosthetic Infection
Authors: Cance Nicolas , Batailler Cécile , Shatrov Jobe , Canetti Robin , Servien Elvire , Lustig Sébastien 
Published: July 2023

Background:
Adequate exposure is essential in revision total knee arthroplasty (RTKA). Tibial tubercle osteotomy (TTO) enhances exposure, but its use is controversial in the setting of periprosthetic infection. The purposes of this study were to determine (1) the rates of complications and revisions due to TTO during RTKA in the setting of a periprosthetic infection, (2) the rate of septic failure, and (3) functional outcomes at a minimum 2-year follow-up.

Methods:
A single-center retrospective study from 2010 to 2020 was performed. The cases of a total of 68 patients who received a TTO during RTKA in the setting of periprosthetic infection with a minimum follow-up of 2 years (mean, 53.3 months; range, 24 to 117 months) were analyzed. Complications and revisions due to TTO were reported. The functional outcomes were assessed using the Knee Society Score (KSS) and range of motion.

Results:
Seven knees (10.3%) had complications secondary to the TTO (3 had fracture-displacement of the TTO; 2, nonunion; 1, delayed union; and 1, wound dehiscence). The mean time to union (and standard deviation) was 3.8 ± 3.2 months (range, 1.5 to 24 months). Two knees (2.9%) underwent a TTO-related revision (1 had wound debridement, and 1 had tibial tubercle osteosynthesis). Eighteen knees (26.5%) had recurrence of infection requiring revision: 17 were managed with debridement, antibiotics, and implant retention (DAIR), and 1 had 2-stage RTKA. Flexion improved after surgery (from a mean of 70° to a mean of 86°; p = 0.009), as did the KSS knee (46.6 to 79; p < 0.001) and function (35.3 to 71.5; p < 0.001) subscores. Overall, 42.6% of infected knees managed with RTKA with the TTO procedure were considered successful without any complication at the last follow-up. Only 2 knees (2.9%) required revision related to the TTO.

Conclusions:
TTO in RTKA involving periprosthetic infection is an effective surgical exposure aid and has excellent rates of union (97.1%) despite the presence of infection. However, the risk of failure because of persistent or recurrent infection remains high in the first 2 years following RTKA for infection.

Level of Evidence:
Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Contralateral Gluteal Compartment Syndrome After Prolonged Use of a Fracture Table in a Scissoring Position
Authors: Gunn Jenna L. , Yatsonsky David , Pasquinelly Adam , Kosco Ethan , Schwartz Tyler G. , Sanford Christopher , Georgiadis Gregory M. 
Published: July 2023

Case:
A 62-year-old Caucasian man presented with a comminuted subtrochanteric fracture after a low-energy fall. Physical examination postoperatively revealed a firm hard gluteal compartment in the contralateral buttocks. The patient underwent a fasciotomy, using the Kocher-Langenbeck approach, to release the gluteus maximus and lateral thigh fascia. At the most recent 6-month follow-up, gluteal function was intact with no long-term sequelae from compartment syndrome.

Conclusion:
Prolonged positioning on a fracture table can result in gluteal compartment syndrome of the contralateral extremity.
Notaries at Risk: Urgent Need for Legal Protection Against Criminal Acts
Authors: Setiawati Yuni , Salim Lendra Akbar , Melati Ayu Sekar , Chesar Wery 
Published: July 2023

This study aims to address the legal protection issues faced by notaries in relation to potential criminal acts and proposes ideas for regulating legal protection. Utilizing a normative legal research approach, data was collected through literature reviews, document analysis, and legal interviews, with conceptual and legal framework analysis conducted. The results reveal a lack of legal harmonization between notarial law and criminal law, which challenges the provision of adequate legal protection for notaries. Harmonization of legal provisions is critical to ensure optimal notarial services and protect against potential criminal acts. The findings emphasize the urgency of implementing legal provisions for notaries' adequate protection and offer valuable insights for policymakers and legal practitioners in crafting effective legal frameworks.
Highlights:

Legal harmonization between notarial and criminal law is needed for adequate protection of notaries.

Protection is necessary for optimal services and protection against criminal acts.

Harmonizing legal provisions is critical for effective protection.

Keywords: Notarial Law, Legal Protection, Criminal Acts, Harmonization, Professional Duties
Preferences for coordinated care for rare diseases: discrete choice experiment
Authors: Morris Stephen , Walton Holly , Simpson Amy , Leeson-Beevers Kerry , Bloom Lara , Hunter Amy , Ramsay Angus I G , Fulop Naomi J , Chitty Lyn S , Kai Joe , Sutcliffe Alastair G , Kokocinska Maria , Kerecuk Larissa , Taylor Christine A , Ng Pei Li 
Published: July 2023

Abstract

Background
Evidence suggests that coordination of care for people affected by rare diseases is poor. In order to improve the way that care is coordinated it is necessary to understand the preferences of people affected by these conditions, and providers. The aim of this study was to examine patient, parent and carer, and health care professional preferences for different attributes of care coordination for people affected by rare diseases. We conducted a discrete choice experiment using online surveys. There were no restrictions on participants in terms of rare conditions, demographic factors other than age, or geographical location within the UK. Choice scenarios were based on the following attributes: annual cost of attending appointments; access to health records; access to clinical expertise; support of a care coordinator; access to a specialist centre; and, the existence of a documented plan for emergency care. Data were analysed using alternative-specific conditional logit regression models.
Results
Valid responses were obtained from 996 individuals (528 patients, 280 carers, 188 health care professionals) between August and December 2019. All attributes significantly influenced the type of service respondents preferred. Patients, carers and health professionals’ preferences for care coordination were influenced by: the cost of attending appointments; access to health records; clinical expertise; role of care coordinators; access to specialist centres; and the existence of plan for emergency care. There were no statistically significant differences in the preferences between patients and carers. Preferences of health professionals differed to those of patients and carers. Both patients and carers selected responses which granted them a greater degree of autonomy in relation to the role of care coordinators, whereas health professionals preferred services where care coordinators had more autonomy. Health care professionals also expressed a stronger preference for a documented formal emergency plan to be in place.
Conclusions
The findings highlight that people value better coordinated care, in line with policy documents emphasising commitments to coordinated care for people affected by rare diseases. This study highlights the factors that could be included in service provision as ways of improving the coordination of care for people affected by rare diseases.
Molecular Aggregates Associated THz Coherent Vibrations Contribute to Enhancements of Emission Efficiencies
Authors: Wei Yu-Chen , Chen Bo-Han , Ye Ren-Siang , Huang Hsing-Wei , Su Jia-Xuan , Chen Kai , Hsu Liang-Yan , Chi Yun , Lu Chih-Hsuan , Yang Shang-Da , Chou Pi-Tai 
Published: July 2023

Abstract
The control of excited-state vibrational and electronic energy flows in molecular solids has a considerable impact on the performance of optoelectronic devices. In this study, we applied a novel ultrafast pump-probe system with 3.2 fs resolution to demonstrate that the aggregated Pt(II) complex 4H, an efficient near-infrared emitter, exhibits prominent single-mode vibrational coherence (VC) with a frequency of 32 cm−1 (~ 0.96 THz) in the excited state. This single-mode VC is associated with the collective out-of-plane motions induced by intermolecular metal-metal-to-ligand charge transfer transitions, which occur through ultrafast intersystem crossings with lifetimes of 150 fs. Similar single-mode VC characteristics were observed in analogues of 4H and other Pt(II) complexes with intense NIR emission. The conservation of single-mode VC enables excited-state deactivation to proceed along low-frequency coordinates, which contributes to the suppression of nonradiative decay rates and causes highly intense near-infrared emission in aggregated Pt(II) complexes. These novel results highlight the importance of VC in understanding nonradiative processes, elucidating the foundations of VC in molecular solid, which serve as a benchmark for evolving the device performance.