bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modified entropy based least square channel estimation technique for 5G massive multiple input multiple output universal filtered multicarrier systems
Authors: Shaik Nilofer , Malik Praveen Kumar 
Published: February 2023

Abstract
These days’ Massive multiple input multiple output (mMIMO) systems have become popular because of their enhanced data transmission rates, robustness against multipath fading, enhanced spectral efficacy, and ability to communicate with a more significant number of users with immense coverage. The critical challenge of the mMIMO systems is precisely replenishing the channel state information (CSI), along with the synchronization between receiver and transmitter. The CSI has recovered with the help of various channel estimation (CE) techniques. This paper presents a modified entropy-based least square CE technique for 5G mMIMO-UFMC systems. The proposed CE technique performance is novel and better than the Least Square (LS) and minimum mean square error (MMSE) CE techniques. The proposed CE technique was evaluated using MATLAB, and its performance results are shown in the simulation. The performance results of the proposed CE are evaluated based on the mean square error (MSE) and bit error rate (BER) of the obtained signal. The executed results prove that the proposed CE is efficient compared to conventional CE methods. The performance of the MCM techniques with respect to the proposed CE is also presented in this paper. This paper also explains the analytical assessment of the LS, MMSE, and MELS CE techniques. The results show that at high values of SNR, the proposed algorithm outperforms the LS and MMSE for both BER and MSE.
A stage-wise non-Gaussian statistical process control strategy
Authors: Mishra Bhagwan Kumar , Das Anupam 
Published: February 2023

Abstract
The article delves into the development of a Non-Gaussian Process Monitoring Strategy for a Copper Cathode Manufacturing Unit (CCMU). The monitoring strategy being devised highlighted the issue of multi-stage process monitoring via the usage of Multi-block Independent Component Analysis (MBICA) techniques. MBICA is the multi-block variant of ICA technique which is prevalently used for process laden with non-Gaussian or non-normal data. Development of the monitoring strategy involved detection of fault(s) and their subsequent diagnosis. Detection of fault(s) was carried out by employment of I2 control chart whose control limit was established via Bootstrap procedure. The diagnosis of the detected fault was carried out by employment of fault diagnostic statistic. An amalgamation of MBICA and Multivariate Exponentially Weighted Moving Average (MEWMA) are also known as MBICA-MEWMA approach was also proposed for detection of incipient fault(s). The monitoring strategy thus developed was showcased for a CCMU which specialised in the manufacture of copper cathode which has got varied practical applications. The monitoring strategy thus devised was able to detect and diagnose the faults with appreciable accuracy.
Microstructure, mechanical and electrochemical studies of dissimilar friction stir welded aluminium alloys
Authors: Padmavathi Tejavath , Naik Banoth Balu 
Published: February 2023

Abstract
In the present investigation, the influence of tool rotational speed (900, 1100, 1300, and 1500 rpm) on microstructure, mechanical characteristics, and corrosion behavior of friction stir welding (FSW) of dissimilar Al5083–6061 alloys was studied. Optical and scanning electron microscopes were used to study the microstructural features. The grain size measured at the stir zone (SZ) decreased considerably in contrast with the base materials (BM) but increased with tool rotational speed. The mixing degrees of two materials at the SZ are enhanced by increasing rotational speeds. The mechanical properties, such as hardness and tensile properties, were studied using Vicker’s hardness tester and universal testing machine. The hardness of the weld joints is inferior to that of the base metal, and uniform hardness distribution and the highest average hardness in SZ were obtained at 1100 rpm. The higher strength and elongation of 202 MPa and 5.2%, respectively, were achieved at 1100 rpm, with joint efficiency of 65%, due to optimum heat input, and the lowest tensile strength and elongation of 156 MPa and 3.2%, respectively, were obtained at 1300 rpm with a joint efficiency of 50% due to excess heat input. It is curious to note that an increase in tensile elongation accompanies the enhancement of weld strength. The fracture occurred at the retreating side of the heat-affected zone as it is the weakest zone in the FSWed joint. Different corrosion tests, such as immersion, open circuit potential, and Tafel polarization tests, were carried out using an electrochemical workstation. The corrosion findings showed that the corrosion resistance of the samples increased after the welding, and the highest corrosion resistance was obtained at 1100 rpm.
Interpolated Apéry numbers, quasiperiods of modular forms, and motivic gamma functions
Authors: Golyshev Vasily , Zagier Don 
Published: February 2023

We extend the definitions of the sequences used by Apéry in his proof of the irrationality of

ζ
(
3
)

\zeta (3)

to non-integral values of the index and relate the value with index

−
1

/

2

-1/2

to the central value of the

L
L

-series of the unique normalized cusp form of weight 4 on

Γ
0

(
8
)

\Gamma _0(8)

. We also discuss the notion of quasiperiods of modular forms and relate the Apéry numbers of other half-integral indices to these. We further explain the conjectural relationship of the Taylor expansion around 0 of a different interpolation of the Apéry numbers to a generalized version of the Gamma Conjecture, and discuss interpretations of the various results with families of Calabi-Yau manifolds, mirror symmetry, and motivic gamma functions.
High Dynamic Range Dual-Modal White Light Imaging Improves the Accuracy of Tumor Bed Sampling After Neoadjuvant Therapy for Breast Cancer
Authors: Zhang Meng , Liao Jun , Jia Zhanli , Qin Chenchen , Zhang Lingling , Wang Han , Liu Yao , Jiang Cheng , Han Mengxue , Li Jinze , Wang Kun , Wang Xinran , Bu Hong , Yao Jianhua , Liu Yueping 
Published: February 2023

AbstractObjectivesAccurate evaluation of residual cancer burden remains challenging because of the lack of appropriate techniques for tumor bed sampling. This study evaluated the application of a white light imaging system to help pathologists differentiate the components and location of tumor bed in specimens.MethodsThe high dynamic range dual-mode white light imaging (HDR-DWI) system was developed to capture antiglare reflection and multiexposure HDR transmission images. It was tested in 60 specimens of modified radical mastectomy after neoadjuvant therapy. We observed the differential transmittance among tumor tissue, fibrosis tissue, and adipose tissue.ResultsThe sensitivity and specificity of HDR-DWI were compared with x-ray or visual examination to determine whether HDR-DWI was superior in identifying tumor beds. We found that tumor tissue had lower transmittance (0.12 ± 0.03) than fibers (0.15 ± 0.04) and fats (0.27 ± 0.07) (P &lt; .01).ConclusionsHDR-DWI was more sensitive in identifying fiber and tumor tissues than cabinet x-ray and visual observation (P &lt; .01). In addition, HDR-DWI could identify more fibrosis areas than the currently used whole slide imaging did in 12 samples (12/60). We have determined that HDR-DWI can provide more in-depth tumor bed information than x-ray and visual examination do, which will help prevent diagnostic errors in tumor bed sampling.
Modular segregation drives causality of the dynamic oscillatory network responses during threat processing
Authors: Gonzalez-Escamilla Gabriel , Chirumamilla Venkata C , Koirala Nabin , Anwar Abdul R , Tüscher Oliver , Vogt Johannes , Horstmann Phillip , Meyer Benjamin , Bonanno George A , Groppa Sergiu , Muthuraman Muthuraman 
Published: February 2023

Abstract
Physiological responses to threat and stress stimuli entrain synchronized neural oscillations among cerebral networks. Network architecture and adaptation may play a critical role in achieving optimal physiological responses, while alteration can lead to mental dysfunction.
We reconstructed cortical and sub-cortical source time series from high-density electroencephalography, which were then fed into community architecture analysis. Dynamic alterations were evaluated in terms of flexibility, clustering coefficient and global and local efficiency, as parameters of community allegiance. Transcranial magnetic stimulation was applied over the dorsomedial prefrontal cortex during the time window relevant for physiological threat processing and effective connectivity was computed to test the causality of network dynamics.
A theta band-driven community re-organization was evident in key anatomical regions conforming the central executive, salience network and default mode networks during instructed threat processing. Increased network flexibility entrained the physiological responses to threat processing. The effective connectivity analysis showed that information flow differed between theta and alpha bands and were modulated by transcranial magnetic stimulation in salience and default mode networks during threat processing.
Theta oscillations drive dynamic community network re-organization during threat processing. Nodal community switches may modulate the directionality of information flow and determine physiological responses relevant to mental health.
Effect of Coronavirus Disease 2019 Lockdowns on Identification of Advanced Human Immunodeficiency Virus Disease in Outpatient Clinics in Uganda
Authors: Nalintya Elizabeth , Sekar Preethiya , Kavuma Paul , Kigozi Joanita , Ssuna Martin , Kirumira Paul , Naluyima Rose , Namuli Teopista , Musa Fred Turya , Skipper Caleb P , Hullsiek Kathy Huppler , Ellis Jayne , Boulware David R , Meya David B , Rajasingham Radha 
Published: February 2023

Abstract
Using data from 67 Ugandan human immunodeficiency virus (HIV) clinics (July 2019–January 2022), we report a 40% (1005/1662) reduction in the number of people with HIV presenting to care after August 2021 compared to prepandemic levels, with a greater proportion presenting with advanced HIV disease (20% vs 16% in the pre–coronavirus disease 2019 period).
Warm versus cold blood cardioplegia in paediatric congenital heart surgery: a randomized trial
Authors: Stoica Serban , Smartt Helena J M , Heys Rachael , Sheehan Karen , Walker-Smith Terrie , Parry Andrew , Beringer Richard , Ttofi Iakovos , Evans Rebecca , Dabner Lucy , Ghorbel Mohamed T , Lansdowne William , Reeves Barnaby C , Angelini Gianni D , Rogers Chris A , Caputo Massimo 
Published: February 2023

Abstract

OBJECTIVES
Intermittent cold blood cardioplegia is commonly used in children, whereas intermittent warm blood cardioplegia is widely used in adults. We aimed to compare clinical and biochemical outcomes with these 2 methods.

METHODS
A single-centre, randomized controlled trial was conducted to compare the effectiveness of warm (≥34°C) versus cold (4–6°C) antegrade cardioplegia in children. The primary outcome was cardiac troponin T over the 1st 48 postoperative hours. Intensive care teams were blinded to group allocation. Outcomes were compared by intention-to-treat using linear mixed-effects, logistic or Cox regression.

RESULTS
97 participants with median age of 1.2 years were randomized (49 to warm, 48 to cold cardioplegia); 59 participants (61%) had a risk-adjusted congenital heart surgery score of 3 or above. There were no deaths and 92 participants were followed to 3-months. Troponin release was similar in both groups [geometric mean ratio 1.07; 95% confidence interval (CI) 0.79–1.44; P = 0.66], as were other cardiac function measures (echocardiography, arterial and venous blood gases, vasoactive-inotrope score, arrhythmias). Intensive care stay was on average 14.6 h longer in the warm group (hazard ratio 0.52; 95% CI 0.34–0.79; P = 0.003), with a trend towards longer overall hospital stays (hazard ratio 0.66; 95% CI 0.43–1.02; P = 0.060) compared with the cold group. This could be related to more unplanned reoperations on bypass in the warm group compared to cold group (3 vs 1).

CONCLUSIONS
Warm blood cardioplegia is a safe and reproducible technique but does not provide superior myocardial protection in paediatric heart surgery.
Health Emergency and Asylum Law in the European Union
Authors: Nicolosi Salvatore Fabio 
Published: February 2023

Abstract
The rapid spread of COVID-19 in Europe has led to the further deterioration of the crisis concerning the application of the provisions of European Union (EU) asylum law in most Member States. Accordingly, this article aims to shed light on the impact that the health emergency is having on the Common European Asylum System (CEAS). This requires a twofold legal analysis. First, the article discusses whether health emergencies, like that caused by COVID-19, should affect the scope of States’ obligations stemming from the CEAS, such as the principle of non-refoulement and access to asylum procedures. In this connection, it reviews, in light of international law obligations and the EU border control regime, the policy responses and legislative measures adopted by EU Member States during the first few weeks of the pandemic that resulted in the closure of borders to asylum seekers. Secondly, the article investigates whether the CEAS legal toolbox contains adequate provisions that can be applied in emergency situations. Thus it analyses the impact of the health emergency on reception conditions for asylum seekers. Based on the findings of this twofold analysis, it is concluded that certain rights, such as the right to seek asylum, cannot be suspended – not even during a situation of health emergency – and that it is all the more urgent to redesign a CEAS that takes account of the challenges posed by future situations of health emergency.
Breast Angiosarcoma: Imaging Features With Histopathologic Correlation
Authors: Kapoor Megha M , Yoon Esther C , Yang Wei T , Patel Miral M 
Published: February 2023

AbstractBreast angiosarcoma is a rare malignancy of endothelial origin that can be categorized as primary angiosarcoma (PAS) or secondary angiosarcoma (SAS) based on etiology. Primary angiosarcoma typically affects younger women with no known risk factors, whereas SAS of the breast typically develops in older women who have undergone breast cancer treatment. There are two types of SAS, one that develops in the setting of chronic lymphedema and one that develops as a radiation-associated neoplasm after breast-conserving therapy (BCT). Clinically, PAS often presents as a palpable mass that may be rapidly growing, whereas SAS presents with skin changes such as erythematous plaques or nodules or with areas of skin discoloration. Mammographically, the appearance of PAS can be nonspecific and may be obscured by the dense tissue that is characteristic of the young patient population it typically affects. Cases of mammographically occult PAS have been visible at US and MRI. Mammography and US have been found to be less sensitive than MRI for the diagnosis of secondary radiation-associated angiosarcoma. Angiosarcomas, both PAS and SAS, are graded, depending on degree of differentiation, as low, intermediate, or high grade. Endothelial markers such as ERG and CD31 immunohistochemical stains are used to support the diagnosis of angiosarcomas. In this article, we review the clinical presentation, imaging findings, associated histopathology, and treatment of primary and secondary breast angiosarcoma.
Unrecognized sexual dysfunction in gay and bisexual men after prostate cancer treatment: the antecedents and impact of anodyspareunia
Authors: Wheldon Christopher W , Bates Alex J , Polter Elizabeth J , Rosser B R Simon , Kapoor Aditya , Talley Kristine M C , Haggart Ryan , Kohli Nidhi , Konety Badrinath R , Mitteldorf Darryl , Ross Michael W , West William , Wright Morgan 
Published: February 2023

AbstractBackgroundAnodyspareunia may be an adverse outcome of prostate cancer (PCa) treatment for gay, bisexual, and other men who have sex with men (GBM).AimThe aims of this study were to (1) describe the clinical symptoms of painful receptive anal intercourse (RAI) in GBM following PCa treatment, (2) estimate the prevalence of anodyspareunia, and (3) identify clinical and psychosocial correlates.MethodsThis was a secondary analysis of baseline and 24-month follow-up data from the Restore-2 randomized clinical trial of 401 GBM treated for PCa. The analytic sample included only those participants who attempted RAI during or since their PCa treatment (N = 195).OutcomesAnodyspareunia was operationalized as moderate to severe pain during RAI for ≥6 months that resulted in mild to severe distress. Additional quality-of-life outcomes included the Expanded Prostate Cancer Index Composite (bowel function and bother subscales), the Brief Symptom Inventory–18, and the Functional Assessment of Cancer Therapy–Prostate.ResultsOverall 82 (42.1%) participants reported pain during RAI since completing PCa treatment. Of these, 45.1% experienced painful RAI sometimes or frequently, and 63.0% indicated that the pain was persistent. The pain at its worst was moderate to very severe for 79.0%. The experience of pain was at least mildly distressing for 63.5%. Painful RAI worsened for a third (33.4%) of participants after completing PCa treatment. Of the 82 GBM, 15.4% were classified as meeting criteria for anodyspareunia. Antecedents of anodyspareunia included a lifelong history of painful RAI and bowel dysfunction following PCa treatment. Those reporting symptoms of anodyspareunia were more likely to avoid RAI due to pain (adjusted odds ratio, 4.37), which was negatively associated with sexual satisfaction (mean difference, −2.77) and self-esteem (mean difference, −3.33). The model explained 37.2% of the variance in overall quality of life.Clinical ImplicationsCulturally responsive PCa care should include the assessment of anodyspareunia among GBM and explore treatment options.Strengths and LimitationsThis is the largest study to date focused on anodyspareunia among GBM treated for PCa. Anodyspareunia was assessed with multiple items characterizing the intensity, duration, and distress related to painful RAI. The external validity of the findings is limited by the nonprobability sample. Furthermore, the cause-and-effect relationships between the reported associations cannot be established by the research design.ConclusionsAnodyspareunia should be considered a sexual dysfunction in GBM and investigated as an adverse outcome of PCa treatment.
Dual Functions oflabialResolve the Hox Logic of Chelicerate Head Segments
Authors: Gainett Guilherme , Klementz Benjamin C , Blaszczyk Pola O , Bruce Heather S , Patel Nipam H , Sharma Prashant P 
Published: February 2023

AbstractDespite an abundance of gene expression surveys, comparatively little is known about Hox gene function in Chelicerata. Previous investigations of paralogs of labial (lab) and Deformed (Dfd) in a spider have shown that these play a role in tissue maintenance of the pedipalp segment (lab-1) and in patterning the first walking leg identity (Dfd-1), respectively. However, extrapolations of these data across chelicerates are hindered by the existence of duplicated Hox genes in arachnopulmonates (e.g., spiders and scorpions), which have resulted from an ancient whole genome duplication (WGD) event. Here, we investigated the function of the single-copy ortholog of lab in the harvestman Phalangium opilio, an exemplar of a lineage that was not subject to this WGD. Embryonic RNA interference against lab resulted in two classes of phenotypes: homeotic transformations of pedipalps to chelicerae, as well as reduction and fusion of the pedipalp and leg 1 segments. To test for combinatorial function, we performed a double knockdown of lab and Dfd, which resulted in a homeotic transformation of both pedipalps and the first walking legs into cheliceral identity, whereas the second walking leg is transformed into a pedipalpal identity. Taken together, these results elucidate a model for the Hox logic of head segments in Chelicerata. To substantiate the validity of this model, we performed expression surveys for lab and Dfd paralogs in scorpions and horseshoe crabs. We show that repetition of morphologically similar appendages is correlated with uniform expression levels of the Hox genes lab and Dfd, irrespective of the number of gene copies.
DeepBIO: an automated and interpretable deep-learning platform for high-throughput biological sequence prediction, functional annotation and visualization analysis
Authors: Wang Ruheng , Jiang Yi , Jin Junru , Yin Chenglin , Yu Haoqing , Wang Fengsheng , Feng Jiuxin , Su Ran , Nakai Kenta , Zou Quan , Wei Leyi 
Published: February 2023

Abstract
Here, we present DeepBIO, the first-of-its-kind automated and interpretable deep-learning platform for high-throughput biological sequence functional analysis. DeepBIO is a one-stop-shop web service that enables researchers to develop new deep-learning architectures to answer any biological question. Specifically, given any biological sequence data, DeepBIO supports a total of 42 state-of-the-art deep-learning algorithms for model training, comparison, optimization and evaluation in a fully automated pipeline. DeepBIO provides a comprehensive result visualization analysis for predictive models covering several aspects, such as model interpretability, feature analysis and functional sequential region discovery. Additionally, DeepBIO supports nine base-level functional annotation tasks using deep-learning architectures, with comprehensive interpretations and graphical visualizations to validate the reliability of annotated sites. Empowered by high-performance computers, DeepBIO allows ultra-fast prediction with up to million-scale sequence data in a few hours, demonstrating its usability in real application scenarios. Case study results show that DeepBIO provides an accurate, robust and interpretable prediction, demonstrating the power of deep learning in biological sequence functional analysis. Overall, we expect DeepBIO to ensure the reproducibility of deep-learning biological sequence analysis, lessen the programming and hardware burden for biologists and provide meaningful functional insights at both the sequence level and base level from biological sequences alone. DeepBIO is publicly available at https://inner.wei-group.net/DeepBIO.
From animal collective behaviors to swarm robotic cooperation
Authors: Duan Haibin , Huo Mengzhen , Fan Yanming 
Published: February 2023

ABSTRACT
The collective behaviors of animals, from schooling fish to packing wolves and flocking birds, display plenty of fascinating phenomena that result from simple interaction rules among individuals. The emergent intelligent properties of the animal collective behaviors, such as self-organization, robustness, adaptability and expansibility, have inspired the design of autonomous unmanned swarm systems. This article reviews several typical natural collective behaviors, introduces the origin and connotation of swarm intelligence, and gives the application case of animal collective behaviors. On this basis, the article focuses on the forefront of progress and bionic achievements of aerial, ground and marine robotics swarms, illustrating the mapping relationship from biological cooperative mechanisms to cooperative unmanned cluster systems. Finally, considering the significance of the coexisting-cooperative-cognitive human-machine system, the key technologies to be solved are given as the reference directions for the subsequent exploration.