bluuebunny/crossref_metadata_2025_split huggingface dataset:
Benincasa Hispida Reversed D-galactose-induced oxidative Stress And Neurodegeneration-Mediated Cognitive Impairment In Aged Rats.
Authors: RC Pooja , DR Bharathi 
Published: September 2023

Abstract
Introduction: Age-related cognitive impairment is a common issue that is frequently brought on by oxidative stress and neurodegeneration in the brain. D-gal is a sugar moiety that has been linked to aging and cognitive disorders. This disease's prevalence is expected to rise linearly by 2050.
Material & methods: Benincasa hispida, commonly known as wax gourd or winter melon, is a widely consumed vegetable with various medicinal properties. it belongs to the family of Cucurbitaceae. This study evaluates the neuroprotective role of a hydro-ethanolic seed extract of Benincasa hispida(BH) against D-gal-induced aging in rats. Healthy male rats were divided into six groups: The control group received normal saline, donepezil (2 mg/kg b.w.t., i.p.); D-gal (300 mg/kg b.w.t., i.p.); D-gal +BH (150 mg/kg b.w.t., o.p.); D-gal BH (250 mg/kg b.w.t., o.p.); and D-gal BH (300 mg/kg b.wt.
Results and discussion: Behavioural, brain biochemical, and histopathological changes were assessed after treatment. The results of the behavioral study depicted that D-gal significantly reduces spontaneous alternation and locomotor activity, indicating behavioral and cognitive impairment. Biochemical studies showed that D-gal significantly increases oxidative stress in rat brains. Histopathological study showed that D-gal disturbs the normal architecture of hippocampal and cortical cells, indicating degeneration in these brain areas. D-gal and BH co-treatment for 42 days attenuated the behavioral, biochemical, and neuroanatomic damages caused by D-gal; it markedly suppressed the D-gal-induced oxidative stress and AChE activity in the brain and maintained the normal cellular architecture in hippocampal and cortical areas.
Conclusion: Thus, this study shows that BH can protect the brain from the adverse effects of D-gal (e.g., memory loss and cognitive impairment) by modulating oxidative stress.
Homocysteine contributes to atherogenic transformation of the aorta in rabbits in the absence of hypercholesterolemia
Authors: Tehlivets Oksana , Almer Gunter , Brunner Markus S. , Lechleitner Margarete , Sommer Gerhard , Kolb Dagmar , Leitinger Gerd , Diwoky Clemens , Wolinski Heimo , Habisch Hansjörg , Opriessnig Peter , Bogoni Francesca , Pernitsch Dominique , Kavertseva Maria , Bourgeois Benjamin , Kukilo Jelena , Tehlivets Yuriy G. , Schwarz Andreas N. , Züllig Thomas , Bubalo Vladimir , Schauer Silvia , Groselj-Strele Andrea , Hoefler Gerald , Rechberger Gerald N. , Herrmann Markus , Eller Kathrin , Rosenkranz Alexander R. , Madl Tobias , Frank Sasa , Holzapfel Gerhard A. , Kratky Dagmar , Mangge Harald , Hörl Gerd 
Published: September 2023

Abstract
Atherosclerosis, the leading cause of cardiovascular disease, cannot be sufficiently explained by established risk factors such as cholesterol. Elevated plasma homocysteine (Hcy) is an independent risk factor for atherosclerosis and is closely linked to cardiovascular mortality. However, its role in atherosclerosis has not been fully clarified. We have previously shown that rabbits fed a diet deficient in B vitamins and choline (VCDD), required for Hcy degradation, exhibit an accumulation of macrophages and lipids in the aorta, impairment of its biomechanical properties, and disorganization of aortic collagen in the absence of hypercholesterolemia and an aggravation of atherosclerosis in its presence. In the current study, plasma Hcy levels were increased by intravenous injections of Hcy into balloon-injured rabbits fed VCDD in the absence of hypercholesterolemia. This led to VCDD-like thin collagen-containing plaques with low levels of macrophages and lipids, massive accumulation of VLDL-triglycerides as well as an impaired K+-induced contraction and acetylcholine-induced relaxation of the aorta compared to rabbits fed VCDD alone. The observed elastin fragmentation and collagen disorganization indicate remodeling of scaffold proteins in response to elevated Hcy. Decreased total protein methylated arginine in blood cells and liver as well as altered metabolic profiles in blood cells, serum, and liver suggest additional mechanisms triggered in response to elevated plasma Hcy levels. We therefore conclude that elevated Hcy contributes to atherogenic transformation of the aorta not only in the presence but also in the absence of hypercholesterolemia.
Biology of development of Cydalima perspectalis (Lepidoptera: Crambidae) in laboratory conditions
Authors: Шармагий А.К. 
Published: September 2023

Количество возрастов у гусениц Cydalima perspectalis при питании на Buxus sempervirens - от пяти до восьми. Гусеницы VIII возраста обнаружены в единичных экземплярах в каждом поколении. Время пребывания на VIII возрасте как в первом, так и во втором поколениях составило 8 суток. Куколки в обоих случаях оказались самцами. Соотношение полов при окукливании на V возрасте составило 1:1 в обоих поколениях, на VI возрасте в первом поколении - 1:1,7, а во втором - 1,3:1. При окукливании на VII возрасте доминировали самцы (1:2). Максимальный процент окукливания наблюдается на VI возрасте, который оказался самым распространенным старшим возрастому исследованных особей самшитовой огневки. Гусеницы самшитовой огневки, отрождившиеся из одних и тех же яйцекладок и находящиеся в одинаковых условиях развивались асинхронно. В обеих генерациях пребывание в фазе гусеницы до окукливания варьировало от 18 до 29 суток. Коэффициент изменчивости для срока пребывании на стадии гусеницы в первом поколении составил 11,7%, во втором 13,3%. При этом большинство гусениц первого поколения на I-IV возрастах, а во втором поколении - I-V возрастах развивались в течение двух-трёх суток. Определены биометрические показатели гусениц по возрастам (длина тела, ширина и высота головной капсулы). Некоторые гусеницы в первом поколении на III и V возрастах образовывали двуслойные коконы в которых пребывали шесть месяцев, сохраняя жизнеспособность, при этом они уменьшались в размерах.
The number of instars of the Cydalima perspectalis caterpillars when feeding on Buxus sempervirens varies from five to eight. Caterpillars of the VIII instar were found in a single specimens in each generation. The time spent at the VIII instar, both in the first and second generations, was 8 days. The pupae in both cases turned out to be males. The sex ratio during pupation at the V instar was 1:1 in both generations, at the VI instar in the first generation - 1:1.7, and in the second - 1.3:1. During pupation at the VII instar, males dominated (1:2). The maximum percentage of pupation is observed at the VI instar, which turned out to be the most common older instar in the studied individuals of the box tree moth. Caterpillars of the boxwood moth hatched from the same egg cluster and under the same conditions developed asynchronously. The duration of the caterpillar phase varied from 18 to 29 days under the same temperature. The coefficient of variability for the period of caterpillar stage in the first generation was 11.7%, in the second 13.3%. At the same time, most caterpillars of the first generation at the I-IV instars, and in the second generation - at the I-V instars developed within two to three days. Biometric indicators of caterpillars in different instars were determined. The maximum growth rates of the head capsule were observed at the III instar. Some caterpillars of the first generation at the III and IV instars formed double-layered cocoons in which they stayed for six months, been alive.
The first record of Adbera quadrifasciata (Curtis, 1829) (Coleoptera: Melandryidae) in the Russia (on fees from the Caucasus)
Authors: Бибин А.Р. 
Published: September 2023

Adbera quadrifasciata (Curtis, 1829) (Coleoptera: Melandryidae) широко распространен в Европе. До настоящего времени он не отмечен восточнее азиатской части Турции. Вид собран в Краснодарском крае и впервые приводится для фауны России.
Adbera quadrifasciata (Curtis, 1829) (Coleoptera: Melandryidae) fairly widespread in Europe. Until now A. quadrifasciata was not recorded east of the Asian part of Turkey. The species was collected in the Krasnodar Territory and is reported for the first time for the fauna of the Russia.
Process optimization of anionic dye (Melioderm HF Brown G) removal from aqueous solution utilizing adsorbent prepared from Labeo rohita fishbone
Authors: Hossain Md. Arafat , Turzo Plabon Islam , Shakil Md. Saidur Rahman , Tuj-Zohra Fatema 
Published: September 2023

Abstract

In this study, the prepared bio-adsorbents from Labeo rohita fishbones were used to remove the anionic acid dye Melioderm HF (High Fastness) Brown G (MHFB) from the aqueous solution. Scanning electron microscopy (SEM) and Fourier-transform infrared spectroscopy (FTIR) were used to analyze the morphology and chemical composition of fishbone powder (FBP) before and after MHFB dye adsorption. In a batch experiment, factors such as initial dye concentration (100–250 mg/mL), contact time (5–180 min), pH of the solution (2.0–8.0), and the adsorbent dosage (1.0–3.5 g/L) were analyzed for their impact on the dye adsorption process. The batch experiments were studied to evaluate the influence of different operational variables such as pH, adsorbent dosage, contact time, and initial concentration of dye and were found optimum at 2, 2 g/L, 120 min, and 200 ppm, respectively, for maximum dye removal (98.33%) at ambient temperature (298 K). The isotherm models demonstrated that dye molecules were adsorbed heterogeneously in multilayer following the Freundlich isotherm (R2 = 0.9300). The data were fitted for pseudo-second-order kinetics. Thus, L. rohita fishbone could be used as a bio-adsorbent to remove anionic dye from tannery effluents at a minimal cost.
Produção colaborativa em ambientes digitais
Authors: Jacob Lilian Cássia Bórnia , Cardoso Maria Julia Ferreira , Peschanski João Alexandre 
Published: September 2023

As plataformas de colaboração aberta mudaram a forma como o conhecimento é elaborado, difundido e consumido. Com objetivos de abrir e aumentar o acesso ao conhecimento, a Wikipédia é, em sua essência, um recurso educacional aberto e uma ferramenta pedagógica aberta, que permite a observação direta e transparente de práticas, conceitos relacionados ao processo de escrita, à pesquisa, à colaboração social e retórica no meio digital. A pesquisa, de caráter bibliográfico, apresenta uma análise de referenciais teóricos selecionados por sua relevância acadêmica e aderência ao contexto da produção colaborativa em ambientes digitais para a promoção do letramento digital e da comunicação em saúde. Traz os aspectos teóricos da utilização da Wikipédia como uma ferramenta de metodologia ativa, enfocando a sua aplicabilidade nas atividades de ensino, pesquisa e extensão, e, assim, as competências adquiridas pelos estudantes, as estruturas de apoio para a prática pedagógica, difusão científica e educação em saúde.
Determinants of Adolescent Sexual and Reproductive Health in Sub-Saharan Africa: Protocol for an Umbrella Review
Authors: Ghadirian Mona Ziba , Omer Khalid , Cockcroft Anne 
Published: September 2023

Background
Adolescents are a large proportion of the population in sub-Saharan Africa and face multiple risks to their health and well-being. Prior systematic reviews have focused on specific adolescent sexual and reproductive health outcomes such as teen pregnancies, HIV/AIDS, and sexually transmitted diseases. A comprehensive synthesis of the influential factors that shape different aspects of adolescent sexual and reproductive health can inform health policy and program development for this important segment of the population.

Objective
This paper presents the protocol for an umbrella review that aims to synthesize the existing knowledge in the literature on the associations among individual, family, and societal factors and sexual and reproductive health outcomes among adolescents in sub-Saharan Africa.

Methods
We will include systematic reviews that identify factors associated with sexual and reproductive health outcomes among adolescents, 10-19 years of age, in sub-Saharan Africa. Reviews can include quantitative and qualitative primary studies with or without meta-analysis. Academic and gray literature searches will identify reviews from PubMed, Scopus, CINAHL, Cochrane Database of Systematic Reviews, ProQuest, Google, and Google Scholar. Two reviewers (MZG and KO) will independently carry out title, abstract, and full text screening, assess methodological quality, and extract data. We will assess the methodological quality of the included studies using the Joanna Briggs Institute standard forms. The review will present findings in narrative form and in tables and will follow PRISMA (the Preferred Reporting Items for Systematic Reviews and Meta-Analyses) reporting guidelines.

Results
A preliminary search in April 2023 found 1351 articles to be screened.

Conclusions
This umbrella review will permit a comprehensive and high-level understanding of the various factors that influence adolescent sexual and reproductive health in sub-Saharan Africa.

Trial Registration
PROSPERO International Prospective Register of Systematic Reviews CRD42023394512; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=394512

International Registered Report Identifier (IRRID)
DERR1-10.2196/51278
Red Internacional de Enfermería en Cuidados Paliativos-Perú: Enfermeras Paliativas Uniendo Esfuerzos
Authors: Parra-Giordano Denisse , Alfaro Rodríguez Maricarmen , Carmona Montoya Xiomara 
Published: September 2023

Introducción: En todo el mundo solo el 14 % de las personas que requieren cuidados paliativos (CCPP) los reciben. En el año 2015, profesionales de enfermería conformaron la Red Internacional de Enfermería en Cuidados Paliativos (RienCupa) en el marco de las Redes Internacionales de Enfermería (RIEs).
Objetivo: Identificar el estado actual de la RienCupa Perú a través de describir sus fortalezas y debilidades, para con ello ofrecer recomendaciones.
Desarrollo: Perú fue el primer país en adherirse al trabajo de redes a través de RienCupa Perú. El trabajo de la Red que se presenta se estructuró en cinco fases: preparación para el despliegue; implementación e identificación de recursos; ejecución y despliegue del proyecto; resultados obtenidos y proyección y actividades futuras. La Red está constituida por ochenta miembros; tiene presencia en seis provincias y en doce instituciones del país. Sus principales fortalezas son el crecimiento personal, institucional y de equipos a nivel nacional e internacional. Una debilidad es el sistema de financiamiento que limita su campo de acción. Las recomendaciones son fortalecer las competencias de sus integrantes en CCPP, gestión, liderazgo y políticas públicas.
Conclusiones: La RienCupa Perú tiene un gran impacto evidenciado por su constitución y su proceso de trabajo, lo que ha permitido el desarrollo de estrategias que contribuyen a la participación solidaria de los equipos para con ello brindar un mejor cuidado de la población a su cargo.
Anticoncepción forzada en mujeres mexicanas realizadas en instituciones públicas de salud: una aproximación etnográfica
Authors: Orozco-Galván Aldo Iván 
Published: September 2023

Introducción: La anticoncepción forzada y bajo coerción en mujeres es un fenómeno de larga data. Existen diversos mecanismos institucionales para asegurar el respeto a los derechos reproductivos de las mujeres, pero en la práctica, sigue ocurriendo la coerción para el uso de anticonceptivos.
Objetivo: Conocer diversas estrategias utilizadas por el personal de salud, para coaccionar la decisión de algunas mujeres de utilizar métodos quirúrgicos o dispositivos anticonceptivos.
Método: Investigación etnográfica realizada en instituciones de salud de la Ciudad de México y el Estado de Querétaro. Participaron 9 mujeres usuarias de los servicios de planificación familiar y 12 miembros del personal de salud. La recolección de información fue mediante entrevistas semi-estructuradas. Se realizó una matriz analítica de las formas de coerción y categorías emergentes.
Resultados: El personal de salud empleó diversas estrategias para intentar convencer a las mujeres de utilizar anticonceptivos después de la atención del parto. Algunas constituyen formas de coerción, como utilizar momentos de vulnerabilidad emocional para hacerlas firmar formatos de consentimiento informado sin estar informadas, provocar miedo o impedir el egreso hospitalario si no se adopta algún método anticonceptivo.
Discusión: Las estrategias utilizadas por el personal se enmarcan en políticas públicas para la promoción de salud, sin embargo, se aplican sin considerar los deseos y necesidades de las mujeres. Los profesionales en muchos casos no son responsables directos de la coerción hacia ellas, pues deben obedecer mandatos institucionales.
Conclusiones: Las políticas de planificación familiar pueden ser utilizadas como dispositivos biopolíticos para controlar la sexualidad y reproducción de las mujeres.
Pengaruh Sinar UV-C terhadap Perubahan Mutu Wortel (Daucus carota L.) Selama Penyimpanan
Authors: Ningsih Nesti Kurnia , Novita Dwi Dian , Tamrin Tamrin 
Published: September 2023

Based on the survey result of vegetable crop production in Indonesia, the national carrot harvest area is 13,398 hectares spread over 16 provinces. Meanwhile, the average carrot production in Lampung Province can reach 16,02 tons/year with a harvested area of 369 hectares (BPS, 2018). Damage to horticultura commodities can occur if the post-harvest handling is not done well. Many problems were found related to the decay of agricultural products due to the development of microorganisms which caused gread losses for farmers. Sterilization with UV lamps is an attempt to kill and eliminate pathogens or spoilage microbes that cause food spoilage. This sterilization aims to determine the effect of UV-C rays on the quality of carrot during storage. This research was conducted using a completely randomized design (CRD) with 2 factors, namely the irradiation distance factor (20 cm, 40 cm, and 60 cm) and the irradiation time (1-, 20, and 30 minutes). The data obtained were analyzed by ANOVA test. In the 60 cm irradiation distance treatment with an irradiation time of 30 minutes is the recommended storage distance because it can suppress root growth with an average value of 16,67 %, physical damage 14,58%, and gives the panelists the best assessment of the freshness level parameter with an average value of 3,24 (scale 5), texture with an average value of 3,25 (scale 5), and skin appearance with an average value of 3,15 (scale 5). Keywords: Carrots, Microbes, Influence, UV-C Rays, Radiation
重審中醫瘟疫理論在當代疫情危機中的認知價值和倫理效應
Authors: 程 國斌 
Published: September 2023

LANGUAGE NOTE | Document text in Chinese; abstract also in English.
在對中國古代瘟疫理論和公共衛生的研究中，往往認為傳統中醫學的傳染觀念和瘟疫理論不夠＂科學”和＂精准”，在公共衛生和社會防疫等中觀維度上無法發揮積極作用。但中醫學瘟疫理論，將疫情描述為彌漫性環境風險與人類活動相互作用的動態圖景，不僅具有在特定社會歷史環境和時人認知觀念背景下的時代合理性，相較於現代傳染病學＂傳染鏈”的線性分析模型，對當今疫情也能夠給出一個更具整體性的風險認知模型，具有不可替代的價值。更重要的是，古典瘟疫理論有助於打破傳染鏈交織迭加成群體流行的線性思維所帶來的道德難題，為促成全人類肩並肩面對風險、共同承擔責任與持續性協同抗疫的價值目標，提供一個基於中國文化傳統的論證依據。
In the study of concepts developed in the context of public health management in ancient China, the notion of infectiousness and plague theories in TCM (Traditional Chinese Medicine) are often perceived to have little significance to epidemic prevention and public health today because they are viewed as “unscientific.” This paper, however, argues that the doctrine of yinqi (the epidemic qi) and the concept of infectiousness in TCM present a dynamic interaction between diffuse environmental risks and human activities in a specific spatio-temporal context. The concept of epidemic qi offers a unique cognitive model with which to approach the epidemic risk in a given socio-historical environment that differs from a linear analysis of the “chain of infection” in modern medicine. The paper concludes that the plague theories reflected in TCM are relevant to the contemporary understanding of risk control during a public health crisis.
健康受試者的＂艱難抉擇＂
Authors: 王 嘉琪 , 鄧 蕊 
Published: September 2023

LANGUAGE NOTE | Document text in Chinese; abstract also in English.
以新冠疫苗I期試驗的健康受試者為研究對象，基於深度訪談和虛擬民族志研究方法，採用NVivo11軟體進行編碼分析，發現健康受試者的參與動機多為積極動機，在抉擇過程中曾面臨內外矛盾而深陷糾結與掙扎。文章歸納出新冠疫苗受試者抉擇過程不同階段的動機與行為特點，即：萌生想法——躍躍欲試的受試者；進退狐疑——踽踽獨行的受試者；備受煎熬——忐忑不安的受試者；解惑釋疑——篤定前行的受試者。旨在真實地還原健康受試者的抉擇過程，消除社會偏見，為健康受試者和I期試驗去除污名，提升公眾的認知，增强健康受試者的認同感和歸屬感。
Taking the Phase I trial of the 2019-nCoV vaccine as a case study, this paper examines the motivational and psychological development and behavioral patterns of healthy volunteers who participate in different phases of clinical trials for vaccines. The findings of a series of in-depth interviews and virtual ethnographical studies show that participation in a clinical trial such as that for the 2019-nCoV vaccine is a difficult choice for volunteers, as it entails exposure not only to medical risks but also to social prejudice. The paper provides a detailed account of how the volunteers for the Phase I 2019-nCoV vaccine trials made their choice to participate and how they overcame various doubts and fears to serve as responsible research partners.
Formation initiale à l’enseignement secondaire et formation continue diplômante à l’enseignement primaire en éducation physique à Genève : Quelle(s) tradition(s) d’enseignement ?
Authors: Lenzen Benoît 
Published: September 2023

Cette contribution vise à décrire et analyser l’émergence de deux programmes de formation à l’enseignement de l’éducation physique de l’Université de Genève, au regard des traditions d’enseignement dans lesquels ils sont susceptibles de s’être ancrés : (a) la FORENSEC (enseignement secondaire) ; (b) le DAS MDAS (enseignement primaire). La méthodologie respecte les étapes classiques de l’analyse de documents. L’analyse des principaux documents de références de ces programmes montre qu’ils s’ancrent très majoritairement dans une tradition d’enseignement de l’éducation physique comme éducation à la culture physique et sportive. Cet ancrage résulte à la fois d’un choix conscient du corps enseignant et de facteurs structurels qui y sont favorables, voire le déterminent.
Disruptive Business Model Innovation and Digital Transformation
Authors: Tomičić-Pupek Katarina , Furjan Martina Tomičić , Pihir Igor , Vrček Neven 
Published: September 2023

Abstract

Background
Innovating how organisations run their business is a strategic decision to create more value for customers using or consuming the product and/or service provided. In addition to the incentive of everybody embracing digital transformation, digital technologies, and digital innovation, which frame changes of operating business models today, disruptions, i.e., another incentive that occurs suddenly and impacts globally, all force businesses to adapt and change.

Objectives
This research aims to provide a conceptual model that can be used for organisations to evaluate and propose feasible options for responding to disruptions that influence the businesses’ strategic innovation initiatives while assisting decision-makers in choosing the most appropriate option.

Methods/Approach
Considering internal and external factors that influence digital transformation, the conceptual framework is designed to assess readiness and willingness to transform and create opportunities for future success digitally.

Results
A conceptual framework was developed, tested, and demonstrated in a case study. The case study organisation rated positively the composition of steps to be perf readiness and willingness and choose the most feasible option to change.

Conclusions:
The digital environment and the influence of disruptions force organisations to change. The conceptual framework developed in this research helps the management choose the most feasible change option about the real as-is and the desired to-be state.