bluuebunny/crossref_metadata_2025_split huggingface dataset:
Virtual reality and augmented reality-supported K-12 STEM learning: trends, advantages and challenges
Authors: Jiang Haozhe , Zhu Deqi , Chugh Ritesh , Turnbull Darren , Jin Wu 
Published: January 2025

Abstract
As virtual reality (VR) and augmented reality (AR) continue to become popular, there remains a noticeable gap in understanding their potential for enriching science, technology, engineering, and mathematics (STEM) learning among K-12 students. To address this knowledge gap, this study systematically reviewed 117 articles published from 2010 to 2022 on the basis of the technology-based learning model. Following the PRISMA systematic review method, research methods, research participants, learning devices, learning strategies, advantages and challenges of each article were coded and analyzed. In the last six years (i.e., 2017–2022), the overall number of studies experienced rapid growth. The largest number of articles focused on VR/AR-supported K-12 science learning, followed by mathematics and integrated STEM learning. Smartphone/tablet-based AR was the most widely used technology, while very few studies used dedicated immersive AR devices. Most studies focused on the elementary school stage, while VR/AR-supported STEM learning at senior high schools was underexplored. Studies tended to measure the effectiveness of VR/AR by quantitative methods. Situated learning, task-based learning, and game-based learning were the most widely used learning strategies in VR/AR-supported K-12 STEM learning. The advantages of VR/AR in K-12 STEM learning include a positive impact on individual learners and on learning and teaching processes. In contrast, VR/AR also poses a series of challenges to learners, teachers, and schools. The challenges learners face include distractions, decreased efficiency and effectiveness, diminished inquiry and imagination, operational issues, and discomfort. Teachers encounter difficulties maintaining classroom control, designing activities, acquiring technical competence, and adapting to the new role of facilitating student-centered learning. Schools grapple with high costs, inadequate infrastructure, a lack of private virtual spaces, and privacy concerns. Based on our findings, we propose six research agendas to enrich studies on VR/AR-supported K-12 STEM learning, along with a series of significant implications for practitioners to effectively address the intricate challenges of VR/AR implementation and fully harness its potential.
On the Effectiveness of Aerosol Extinguishing Agents for Battery Vent Gases and Hydrogen
Authors: Subash Arman Ahamed , Nilsson Elna J. K. , Runefors Marcus 
Published: January 2025

Abstract
It is well known that Lithium-ion batteries in thermal runaway can emit gases with high hydrogen concentrations which, in case of delayed ignition, can cause a gas explosion. Aerosol suppression agents are sometimes used to suppress fires and/or prevent ignition of released gases in such situations. The agent has been studied for suppression of fires (diffusion flames), but less is known about the ability of such aerosols to inert highly reactive gas mixtures. In this paper, a commercially available aerosol suppression agent is mixed with a highly reactive gas mixture representing the gas composition from an NCA battery in thermal runaway as well as with pure hydrogen, and the effect on burning velocity is assessed based on OH-PLIF measurements on a Bunsen-burner type setup. The experiments were complemented by 1D flame simulations using a detailed chemical kinetics scheme including relevant combustible gases and the suppression agent. The results show that, although the agent is highly effective in gaseous form, evaporation of aerosols in the pre-flame-zone is prevented by the lower radiative fraction and results in higher burning velocity of hydrogen-rich mixtures. The local cooling induced by the evaporation of the aerosol in the flame leads to an increased flame area and thereby total burning velocity. This effect is further exaggerated by the preferential diffusion of hydrogen. Therefore, modification of the system is needed before applying for this purpose.
Equine-Facilitated Psychotherapy as a Supplementary Treatment for Patients with Mental and/or Substance Use Disorders: An Observational Study on Treatment Outcome
Authors: Thorpe Christina , Steigen Anne Mari , Nissen-Lie Helene Amundsen , Godtlund Solveig , Walderhaug Espen 
Published: January 2025

Abstract
This study examines whether adult patients (n = 105) with mental and/or substance use disorders benefit from equine-facilitated psychotherapy (EFP)—therapy with horses—in addition to regular treatment. The study used an observational pre-post-study design with two measurement points. Treatment outcomes were measured using standardized self-report instruments reflecting psychological distress (Hopkins Symptom Checklist-10), self-efficacy (General Self-Efficacy Scale-5), quality of life (Quality of Life-5), and emotion regulation (sub-scale from the Severity Indices of Personality Problems-118). All outcome measurements found statistically significant pre-post improvements after the EFP treatment program. The findings suggest that EFP could be a beneficial supplementary treatment for a broad range of patients with mental and/or substance use disorders. However, this observational study cannot establish causation or eliminate confounding variables.
Green Assessment of Sensitive Spectrofluorimetric Methods for Simultaneous Estimation of Formoterol Fumarate and Fluticasone Propionate Using a Micelle-Mediated Approach
Authors: Adawy Hamees A. , Hegazy Maha A. , Saad Samah S. , Boltia Shereen A. 
Published: January 2025

Abstract
Highly sensitive spectrofluorimetric methods were developed for the quantitative estimation of formoterol fumarate dihydrate (FFD) and fluticasone propionate (FP) in both authentic raw materials and marketed dosage forms using a micellar-enhanced spectrofluorimetric approach. The proposed methods are based on the determination of FP in the presence of FFD using the first derivative emission spectrofluorimetry. The peak amplitude of the emission spectra of the formed micellar fluorescence was measured at 465 nm after excitation at 236 nm (λ max of FP).The second method quantifies FFD in the presence of FP using second derivative emission spectrofluorimetry. This method measures the peak amplitude of the emission spectra of the formed micelle at 283 nm, where there is no interference from FP, following excitation at 214 nm. In these methods, the emission spectra of the target drugs are measured after micellar formation, with excitation wavelengths at 214 nm for FFD and 236 nm for FP. The fluorescence intensity was enhanced using β-cyclodextrin as a micellar system after optimizing parameters affecting native fluorescence, such as diluting solvents, surfactants, and varying concentrations of β-cyclodextrin. A linear relationship was observed between the fluorescence intensity and concentration for FP over the range of 50–100 ng/mL and for FFD over the range of 30–700 ng/mL. The developed methods are simple, sensitive, non-extractive, economical, and suitable for routine analysis of FFD and FP in their raw materials and combined marketed dosage forms. The proposed techniques were carefully validated for linearity, accuracy, precision, and specificity according to the International Council for Harmonization (ICH) guidelines, demonstrating high sensitivity with lower limits of detection and quantitation. Additionally, the analytical greenness of the suggested procedures was assessed using the Analytical Greenness Metric Approach (AGREE), the Red–Green–Blue model, and the Green Procedure Analytical Index (GAPI).
Inglorious sufferers: Motivational factors and moral foundations shape compassionate and helping reactions toward suffering norm transgressors
Authors: Lucarini Alice , Fuochi Giulia , DeSteno David , Boin Jessica , Voci Alberto 
Published: January 2025

Abstract
While previous research shows that people's reactions to others' suffering can vary, it remains unclear how these responses differ for targets who have previously transgressed, and which factors drive these changes. In two studies (total N = 899), this paper experimentally investigates how compassionate and helping reactions toward a suffering transgressor change depending upon: (a) the target’s motivation (altruistic vs egoistic vs control) for the transgression (Study 1); (b) the nature of the transgression in terms of moral foundation (Care vs Fairness) of the disrespected (vs respected) norm (Study 2). Study 1 supported the role of motivational factors: transgressing for altruistic purposes increased compassionate emotions toward the suffering target, compared to when the target’s motivation was egoistic or when no explanation for the target’s actions was provided. Study 2 showed that the Fairness (vs Care) norm, generated more extreme reactions: more negative when a target person violated the norm, more positive when they behaved in line with the norm. Additionally, in both studies, we also found evidence of a moderating effect of dispositional compassion, while analyses performed in a subsample of Study 2 including additional measures also shed light on the mediating cognitive and affective mechanisms of the effect of the kind of norm transgressed on compassionate and helping reactions. Overall, this paper delves into the intricate dynamic underlying individuals’ responses to the suffering of negatively behaving others, providing insights on how and why people react differently to norm violations.
Bioleaching of lanthanum from nickel metal hydride dry battery using siderophores produced by Pseudomonas sp.
Authors: Hegazy Amany S. , Soliman Hoda M. , Mowafy Amr M. , Mohamedin Attiya H. 
Published: January 2025

Abstract
There is still much to be learned about the properties of siderophores and their applications. This study was designed to characterize and optimize the production of the siderophore produced by a marine bacterium Pseudomonas sp. strain ASA235 and then evaluate their use in bioleaching of rare earth elements (REEs) from spent Nickel–metal hydride (NiMH) batteries. The results of both Tetrazolium and Arnowʼs tests indicated that the test organism produces a mixed-type siderophore of pyoverdine family, a result that was confirmed by FT-IR and MALDI-TOFF analyses. Optimization of pH, temperature, incubation period, and iron concentration for siderophore production led to a noticeable shift from 44.5% up to 91% siderophore unit when the test bacterium was incubated at 28 °C and pH 7 after 72 h in the absence of iron. The purified siderophore showed the ability to bleach about 14.8% of lanthanum from the anode of the NiMH battery along with other elements, although in lower amounts. This data put siderophores in distinct focus for further prospective studies intending the bioleaching of such precious elements. The scaling up of this process and optimization would make a big difference in such a green bioleaching strategy, allowing us to recover such precious elements in an environmentally friendly way.
Torsional Performance of Vat-Photopolymerized Tough Resin: Influence of Gauge Length and UV Post-Curing
Authors: Sadaghian H. , Khalilzadehtabrizi S. , Khodadoost S. , Yeon J.H. 
Published: January 2025

Abstract

Background
A myriad of materials, ranging from soft sensors to bone substitutes, undergo torsional loading throughout their operational lifespan. Many of these materials are produced using additive manufacturing (AM) technology due to its broad applicability. Understanding the torsional behavior of these AM components is crucial prior to their utilization. However, research on the torsional behavior of solid additively-manufactured resin polymers remains very limited.

Objective
To address the gap in understanding the torsional behavior of additively-manufactured resin polymers, this study aimed to investigate the effect of varying gage lengths and UV post-curing durations on the torsional capacity, shear modulus, and energy absorption characteristics of these materials.

Methods
Torsion specimens were fabricated using vat photopolymerization (VPP) with AnyCubic UV Tough Resin. The specimens were prepared with different gage lengths (20, 40, 60, and 80 mm) and were subjected to five UV post-curing durations (0, 15, 30, 60, 90, and 120 min). Monotonic torsion was applied to the specimens until failure at a rate of 0.1 revolutions per minute.

Results
The tests revealed ductile failure patterns across all specimens. Longer post-curing times were found to correlate with increased torsional capacities and shear moduli. However, conclusions regarding energy absorption per unit volume remained inconclusive. The results showed that UV exposure had a significantly greater impact on the mechanical properties of the specimens compared to the gage length. Additionally, a normalized trilinear model was proposed to characterize the behavior of additively-manufactured resin polymers under monotonic torsion, which facilitates numerical simulation of material responses in finite element software.
The Renaissance of Reproductive Science: Leonardo da Vinci’s Anatomical Contributions
Authors: Carroll Michael 
Published: January 2025

Abstract
Leonardo de Vinci is considered one of the greatest artists that has ever lived. His work includes the Mona Lisa and The Last Supper are celebrated worldwide. His talents expand beyond his art and his contributions to disciplines such as engineering, astronomy, geometry, botany, geology have revealed is him as a polymath. One discipline where he devoted a considerable amount of time and effort was anatomy. His anatomical notes and drawings can be paralleled to texts books of today. This review explores Leonardo da Vinci’s significant contributions to the study of human anatomy, with a particular focus on reproductive anatomy. Leonardo’s meticulous dissections and detailed anatomical sketches, despite being influenced by the limited scientific understanding and constraints of his time, reveal his deep curiosity and innovative approach. His work, though not widely recognised during his lifetime, laid foundational insights into neuroanatomy, the cardiovascular system, and foetal development. He had a particular interest in reproduction and the genitourinary anatomy and made many anatomical studies in this area. The review also examines the challenges Leonardo faced, such as the lack of preservation techniques and the influence of Galenic teachings, which led to both groundbreaking observations and notable inaccuracies in his anatomical studies or the reproductive system.
Primärversorgung im interprofessionellen Team
Authors: Filmar Tobias , Kloppe Thomas , Schuster Angela , Spreckelsen Ove 
Published: January 2025

Zusammenfassung

Hintergrund
Gemeinwesensorientierte Primärversorgungszentren (PVZ) sollen miteinander verschränkte gesundheitliche und soziale Problemlagen in der Primärversorgung adressieren. Die Poliklinik Veddel befindet sich in einem der ärmsten Stadtteile Hamburgs und bietet eine teambasierte interprofessionelle Primärversorgung an. Vor allem in Deutschland gibt es nur wenige Erfahrungen mit solchen Zentren. Daher soll die tatsächlich erbrachte interprofessionelle Versorgung anhand von Daten aus der Routineversorgung untersucht werden.

Fragestellung
Wie viele Nutzer*innen wurden interprofessionell versorgt? Wie häufig arbeiteten die verschiedenen Berufsgruppen zusammen? Was waren die häufigsten Gründe für interprofessionelle Konsultationen?

Material und Methoden
Es wurde eine Routinedatenanalyse aller interprofessionell betreuten Fälle der Jahre 2020 und 2021 nach Häufigkeit der Themen, Dauer der interprofessionellen Sitzungen und beteiligten Fachbereiche durchgeführt.

Ergebnisse
Es erhielten 98 (2020) bzw. 181 (2021) Nutzer*innen eine interprofessionelle Versorgung (bei etwa 2500–3000 Patienten pro Quartal in der hausärztlichen Praxis). Am häufigsten versorgte die hausärztliche Praxis gemeinsam mit der psychologischen Beratung, gefolgt von der Sozialberatung. Inhaltlich waren psychische Krisen, aufenthaltsrechtliche Fragen, Probleme mit der Wohnsituation oder komplexere Versorgungskoordinationen am häufigsten.

Diskussion
Die Studie deutet darauf hin, dass eine interprofessionelle, teambasierte Versorgung die Verflechtung von psychosozialen und medizinischen Versorgungsbedürfnissen wirksam adressieren kann. Interprofessionelle PVZ wie die Poliklinik Veddel könnten einen wertvollen Beitrag zur Weiterentwicklung der Primärversorgung in Deutschland leisten.
Local knowledges and the right to participate in science
Authors: Massimi Michela 
Published: January 2025

Abstract
I discuss the right to participate in science, which is part of the UN Declaration of Human Rights (1948) and the International Covenant on Economic Social and Cultural Rights (1966). Building on my previous work on this right as an ‘epistemic-cultural’ right, in this paper my goal is to clarify how fulfilling this right requires engaging with varieties of local knowledges that are too often severed in scientific narratives. I tease out three main varieties of local knowledges and highlight their distinctive features and their intersectionalities. In the second part of the paper, I argue that a more careful appreciation of varieties of local knowledges is not only key for the fulfilment of the right to participate in science but also for other human rights. I focus my attention here selectively on the right to food, and right to clean water. I conclude by highlighting the implications of this discussion for ongoing legal debates on rights of nature.
“Hi, I'm Ruan Yuejiao, from Ho Chi Minh City!”: Digital raciolinguistic enregisterment and indexical hijack of the Vietnamese Mandarin accent
Authors: Wan Tsung-Lun Alan 
Published: January 2025

Abstract
This study adopts a raciolinguistic perspective to examine the portrayal and reception of Ruan Yuejiao, a Vietnamese female spouse character created by a Taiwanese male content creator. As a representative of the Taiwanese majority, this content creator utilizes linguistic features to perform a racialized Vietnamese accent and embody a Vietnamese spouse persona, which they believe counters racial stereotypes. This article introduces the concept of indexical hijack to describe how the racial majority imposes new indexical meanings on these mediatized linguistic features, disregarding the perspectives of the Vietnamese community. By highlighting a raciolinguistic listening mode embedded within Taiwan's multicultural discourse, this study reveals how anti-racist actions initiated by the Vietnamese community are reinterpreted by the Taiwanese majority as racist, reflecting the complexities of post-racial multiculturalism in East Asia. (Raciolinguistics, Taiwan, Vietnamese migrants, digital enregisterment, indexicality)*
Environmental correlates of breeding outcomes in Endangered Grey Crowned Cranes Balearica regulorum in agricultural areas of KwaZulu-Natal, South Africa
Authors: Demmer Carmen R. , Demmer Stuart , McIntyre Trevor 
Published: January 2025

Summary
Birds are often used as ecological indicators because they are widely distributed across diverse habitats and display distinct behavioural responses to environmental changes. The Endangered Grey Crowned Crane Balearica regulorum is regarded as a flagship species of Africa’s wetland and grassland habitats, both of which are undergoing substantial transformation to alternative land uses. The delayed reproductive strategies and habitat specialisation of this crane species makes them more vulnerable to extinction, but this risk is further compounded by data paucity. We employed traditional and contemporary survey methods to collect breeding metrics to calculate stage transition probabilities (i.e. egg–hatchling, hatchling–juvenile) and to identify possible macro-environmental factors that either promote or hinder their reproductive output in a key agricultural area in KwaZulu-Natal, South Africa. We found that Grey Crowned Cranes have a low hatching rate of 38.4% (95% confidence interval 29.3–48.4%) and show that this low hatching rate is exacerbated under high rainfall intensity. Multivariate analyses and multi-model inference revealed that successful nest-sites were generally associated with larger open water-bodies, greater distances from shore, and increased proximity to secondary roads, buildings, and natural grasslands. Although increased agricultural activities might promote greater foraging opportunities, the overall breeding outcomes of this species were poor in this key agricultural region. Our findings stress the urgent need for further fine-scale data collection and monitoring activities to better inform conservation strategies for this species. We also encourage future studies to focus on aspects affecting Grey Crowned Crane breeding in regions where proximity to human activities is inevitable.
Rapid Sampling and Polarimetric Statistics of Lightning With a Phased Array Radar
Authors: Goede Vitor , Schvartzman David , Bodine David , Chmielewski Vanna C. , Yu Tian‐You , Bruning Eric , Tzeng Min‐Duan , Stock Michael 
Published: January 2025

AbstractPrevious studies of lightning detection by radar mostly consisted of observations with reflector‐antenna systems yielding slow volume scan times. Phased array radars offer much faster scan times that are likely to capture echoes from propagating lightning channels. Rapidly updated range‐height indicator scans were used to observe severe storms that occurred in central Oklahoma with the fully digital S‐band Horus PAR to examine echoes from lightning plasma. Numerous lightning echoes were observed during the sampling period in good spatial and temporal agreement with lightning mapping array detections of very high frequency radiation sources. Statistically, they result in increased horizontal reflectivity factor, deviations in radial velocity and spectrum width, highly variable differential reflectivity and differential phase, and decreases in correlation coefficient. Results presented also highlight the capability of phased array radars to better observe lightning compared to current radars, and aid in the study of storm electrification and lightning physics.
Oncogenic potential of truncated-Gli3 via the Gsk3β/Gli3/AR-V7 axis in castration-resistant prostate cancer
Authors: Kaushal Jyoti B. , Raut Pratima , Halder Sushanta , Alsafwani Zahraa W. , Parte Seema , Sharma Gunjan , Abdullah K. M. , Seshacharyulu Parthasarathy , Lele Subodh M. , Batra Surinder K. , Siddiqui Jawed A. 
Published: January 2025

Abstract
The functional activation of the androgen receptor (AR) and its interplay with the aberrant Hh/Gli cascade are pivotal in the progression of castration-resistant prostate cancer (CRPC) and resistance to AR-targeted therapies. Our study unveiled a novel role of the truncated form of Gli (t-Gli3) in advancing CRPC. Investigation into Gli3 regulation revealed a Smo-independent mechanism for its activation. Despite lacking a transactivation domain, t-Gli3 relies on androgen receptor variant 7 (AR-V7) for its action. Mechanistically, Gsk3β activation led to the t-Gli3 generation, and inhibition of Gsk3β supported the accumulation of full-length Gli3 expression through a non-canonical mechanism. Knockdown of Gsk3β (Gsk3β KD) reduces CRPC cell proliferation, induces apoptosis via mitochondrial fragmentation, and triggers metabolomic reprogramming. The in vivo studies with Gsk3β KD cells in the mouse prostate resulted in tumor growth retardation compared to scramble cells. RNA-seq HALLMARK Gene Set Enrichment Analysis (GSEA) analysis of Gsk3β KD revealed a positive enrichment of apoptosis, tumor suppressor gene, and negative enrichment of oncogenic pathway. Furthermore, combinational use of a Gsk3β inhibitor with anti-Smo or Gli1 significantly inhibited the CRPC cell growth, which is resistant to individual Smo or Gli1 inhibitor targeting. Intriguingly, solely targeting Gli3 showed effectiveness in inhibiting CRPC cell growth. Overall, our study underscores the clinical significance of Gli3, emphasizing t-Gli3, and provides novel insights into the interplay of the Gsk3β/t-Gli3/AR-V7 axis in CRPC.