bluuebunny/crossref_metadata_2025_split huggingface dataset:
Differential climatic conditions drive growth of Acacia tortilis tree in its range edges in Africa and Asia
Authors: Uni Daphna , Lerner David , Smit Izak , Mzimba Duduzile , Sheffer Efrat , Winters Gidon , Klein Tamir 
Published: January 2023

AbstractPremiseTree growth is a fundamental biological process that is essential to ecosystem functioning and water and element cycling. Climate exerts a major impact on tree growth, with tree species often requiring a unique set of conditions to initiate and maintain growth throughout the growing season. Still, little is known about the specific climatic factors that enable tree growth in savannah and desert tree species. Among the global tree species, Acacia tortilis occupies one of the largest distribution ranges (crossing 6500 km and 54 latitudes), spanning large parts of Africa and into the Middle East and Asia.MethodsHere we collected climate data and monitored Acacia tortilis tree growth (continuous measurements of stem circumference) in its southern and northern range edges in South Africa (SA) and Israel (IL), respectively, to elucidate whether the growth–climate interactions were similar in both edges.ResultsGrowth occurred during the summer (between December and March) in SA and in IL during early summer and autumn (April–June and October–November, respectively). Surprisingly, annual growth was 40% higher in IL than in SA. Within the wide distribution range of Acacia tortilis, our statistical model showed that climatic drivers of tree growth differed between the two sites.ConclusionsHigh temperatures facilitated growth at the hot and arid IL site, while high humidity permitted growth at the more humid SA site. Our results confer an additional understanding of tree growth adaptation to extreme conditions in Acacia's world range edges, a major point of interest with ongoing climate change.
Organic Photovoltaic Catalyst with σ‐π Anchor for High‐Performance Solar Hydrogen Evolution
Authors: Liang Yuanxin , Li Tengfei , Lee Yuhsuan , Zhang Zhenzhen , Li Yawen , Si Wenqin , Liu Zesheng , Zhang Chuang , Qiao Yan , Bai Shuming , Lin Yuze 
Published: January 2023

AbstractEfficient in situ deposition of metallic cocatalyst, like zero‐valent platinum (Pt), on organic photovoltaic catalysts (OPCs) is the prerequisite for their high catalytic activities. Here we develop the OPC (Y6CO), by introducing carbonyl in the core, which is available to σ‐π coordinate with transition metals, due to the high‐energy empty π* orbital of carbonyl. Y6CO exhibits a stronger capability to anchor Pt species and reduce them to metallic state, resulting in more Pt0 deposition, relative to the control OPC without the central σ‐π anchor. Single‐component and heterojunction nanoparticles (NPs) employing Y6CO show enhanced average hydrogen evolution rates of 230.98 and 323.22 mmol h−1 g[OPC]−1, respectively, under AM 1.5G, 100 mW cm−2 for 10 h, and heterojunction NPs yield the external quantum efficiencies of ca. 10 % in 500–800 nm. This work demonstrates that σ‐π anchoring is one efficient strategy for integrating metallic cocatalyst and OPC for high‐performance photocatalysis.
Patient Smoking Status and Postoperative Outcomes: An Integrative Literature Review of Studies Using the ACS NSQIP Data Set
Authors: Devlin Carol A. , Smeltzer Suzanne C. , Yost Jennifer 
Published: January 2023

ABSTRACTTobacco use is associated with poor surgical outcomes and is the leading cause of preventable morbidity and mortality in the United States. Because of the risk for postoperative complications, researchers continue to examine the association between surgical patients’ smoking status and adverse outcomes. This quantitative integrative review synthesizes evidence on the relationship between smoking status and postoperative outcomes according to information in the American College of Surgeons National Surgical Quality Improvement Program data set. The included studies involved 10 procedures and the evaluated outcomes comprise surgical complications (eg, surgical site infection), medical complications (eg, sepsis), and transitions in care (eg, discharge destination). The review results are mixed and are not generalizable because only two studies specified smoking status as a primary variable of interest. To develop policies for perioperative patient smoking cessation, perioperative nurses require additional research results on the relationships between smoking status and standardized variables.
Association of Dipeptidylpeptidase 4 (CD26) With Chondrocyte Senescence and Radiographic Progression in Knee Osteoarthritis
Authors: Chen Yu‐Hsiu , Zhang Xin , Chou Ching‐Heng , Hsueh Ming‐Feng , Attarian David , Li Yi‐Ju , Kraus Virginia Byers 
Published: January 2023

ObjectiveTo evaluate the association of dipeptidylpeptidase 4 (DPP‐4; also known as CD26) with cellular senescence of human cartilage and progression of knee osteoarthritis (OA).MethodsArticular cartilage sections and chondrocytes were acquired from 35 individuals undergoing total knee replacement for OA to evaluate the following: 1) the association between OA severity and established senescence markers (senescence‐associated β‐galactosidase activity and p16), which was quantified using immunohistochemistry and flow cytometry (n = 19 samples); 2) the coexpression of DPP‐4 with established senescence markers, which was assessed using flow cytometry; and 3) expression levels of anabolic and catabolic genes, senescence‐related genes, and senescence‐associated secretory phenotypes in DPP‐4+ and DPP‐4– cells, which were isolated using fluorescence‐activated cell sorting or magnetic‐activated cell sorting (n = 16 samples). The concentration of soluble DPP‐4 was measured in samples of synovial fluid and samples of plasma from the Prediction of Osteoarthritis Progression cohort and then evaluated for association with the severity of radiographic knee OA at baseline (n = 65 samples) and the progression of structural radiographic OA (n = 57 samples) over a 3‐year period.ResultsDPP‐4 expression was associated with higher senescence‐associated β‐galactosidase activity, p16 expression, senescence‐related gene and catabolic gene (ADAMTS5, MMP13, IL6, and IL8) expression, higher senescence‐associated secretory phenotype secretion, and lower anabolic gene (COL2A1 and ACAN) expression in primary chondrocytes. Synovial fluid DPP‐4 concentration was associated with radiographic OA progression (odds ratio 105.32; P = 0.015), proteases (synovial fluid matrix metalloproteinase 1 and matrix metalloproteinase 3), aggrecan degradation (synovial fluid sulfated glycosaminoglycan), indicators of activated macrophages (synovial fluid CD14 and CD163), and inflammation (synovial fluid interleukin‐6).ConclusionOur study identifies DPP‐4 as a key surface marker in senescent chondrocytes and a predictor of radiographic OA progression.image
Gender tagging of named entities using retrieval‐assisted multi‐context aggregation: An unsupervised approach
Authors: Das Sudeshna , Paik Jiaul H. 
Published: January 2023

AbstractInferring the gender of named entities present in a text has several practical applications in information sciences. Existing approaches toward name gender identification rely exclusively on using the gender distributions from labeled data. In the absence of such labeled data, these methods fail. In this article, we propose a two‐stage model that is able to infer the gender of names present in text without requiring explicit name‐gender labels. We use coreference resolution as the backbone for our proposed model. To aid coreference resolution where the existing contextual information does not suffice, we use a retrieval‐assisted context aggregation framework. We demonstrate that state‐of‐the‐art name gender inference is possible without supervision. Our proposed method matches or outperforms several supervised approaches and commercially used methods on five English language datasets from different domains.
The “Nitrogen Effect”: Complexation with Macrocycles Potentiates Fused Heterocycles to Form Halogen Bonds in Competitive Solvents
Authors: Twum Kwaku , Nadimi Sanaz , Osei Frank Boateng , Puttreddy Rakesh , Ojong Yvonne Bessem , Hayward John J. , Rissanen Kari , Trant John F. , Beyeh Ngong Kodiah 
Published: January 2023

AbstractWeak intermolecular forces are typically very difficult to observe in highly competitive polar protic solvents as they are overwhelmed by the quantity of competing solvent. This is even more challenging for three‐component ternary assemblies of pure organic compounds. In this work, we overcome these complications by leveraging the binding of fused aromatic N‐heterocycles in an open resorcinarene cavity to template the formation of a three‐component halogen‐bonded ternary assembly in a protic polar solvent system.
Tuning metabolic efficiency for increased product yield in high titer fed‐batch Chinese hamster ovary cell culture
Authors: Helfer Apolline , Gros Sylvain , Kolwyck Dave , Karst Daniel J. 
Published: January 2023

AbstractHigh demand in manufactured biologics drives the continued need for increased productivity. In this study elevated lactate metabolization resulted in improved metabolic efficiency and cellular productivity for a readily intensified high titer fed‐batch process. Scheduled base or lactate feeds during the stationary growth phase led to increased titers (+9% and +8% respectively) without impacting the overall growth performance. The higher lactate consumption induced by either feed strategy substituted for glutamate catabolism and consequently reduced ammonia build‐up. Direct correlation between increased titers and reduced ammonia levels was shown. Product quality attributes were impacted by both feeding strategies but could be matched with the control process by shortening the cell culture duration while maintaining titer constant.
Oral application of magnesium‐L‐threonate enhances analgesia and reduces the dosage of opioids needed in advanced cancer patients—A randomized, double‐blind, placebo‐controlled trial
Authors: Wu Siyin , Jin Tian , Ma Bingjie , Ji Yun , Huang Xuehua , Wang Peiliang , Liu Xiaoming , Krylov Boris V. , Liu Xianguo , Ma Ke 
Published: January 2023

AbstractPurposeTo investigate the effects of oral administration of magnesium‐L‐threonate, a novel magnesium compound, on the analgesic effect of opioids in patients with advanced cancer.MethodsWe performed a prospective, randomized, double‐blind trial at a tertiary hospital in Shanghai, China. Eligible cancer patients who took opioids orally were assigned randomly to receive L‐TAMS capsules (1.5 g or 2.0 g according to weight) or a placebo (starch capsules). The primary outcome was the increase in the daily oral dose of morphine in each of the two groups, measured at 7, 14, 21, 30, 60, and 90 days during this trial.ResultsA total of 116 patients from the oncology and pain departments, including inpatients and outpatients, were screened; 83 were enrolled. The increases in daily morphine doses began to differ from day 30 (L‐TAMS group 9.85 mg/d vs. Placebo group 20.49 mg/d, p < 0.05); the differences persisted on day 60 (L‐TAMS group 15.96 mg/d vs. Placebo group 29.06 mg/d, p < 0.05) and on day 90 (L‐TAMS group 21.20 mg/d vs. Placebo group 40.44 mg/d, p < 0.01).ConclusionsL‐TAMS outperforms a placebo in enhancing the analgesic effect of opioids and reducing the necessary opioid dosage. Moreover, L‐TAMS can significantly relieve opioid‐induced constipation. These advantages may be beneficial to patients with advanced cancer.
Traditional Plants Used in Southern Brazil as a Source to Wound Healing Therapies
Authors: Antonio Pereira Isabela , Judah Cury Benhur , Kaio Silva Nunes Ruan , Mota da Silva Luisa 
Published: January 2023

AbstractIn southern Brazil, the biodiversity is great and the traditional use of medicinal plants for wound healing has been documented in ethnobotanical studies and pharmacological studies have assessed their wound properties and phytochemistry. Therefore, this study evaluated ethnobotanical surveys regarding medicinal plants used in southern Brazil for wound healing and studies about the healing properties of these plants published between 2000 and 2022. To retrieve articles related to the study, Web of Science, PubMed (NLM), Open Access Journals, Scielo, Lilacs, and Google Scholar, with keywords including medicinal plants, wound healing, and South of Brazil, have been used. As a result, 73 medicinal plants belonging to 39 families were found in ethnobotanical surveys as a traditional resource used for wound healing in southern Brazil, 15 of which were cited more than once. Besides, 14 of these 15 plants were also used as healing agents worldwide. The most cited plant with healing actions in southern Brazil was Symphytum officinale L. (comfrey). From 2000 to date, 44 articles scientifically demonstrated the wound‐healing effects of the southern Brazilian plants found in ethnobotanical surveys reviewed. The folk medicine of southern Brazil presents a variety of medicinal plants for wound‐healing purposes, and scientific data were found for some of those plants. However, the wound‐healing properties of many plants have yet to be investigated, and the current literature still needs more phytochemical information about the plants studied. Aside from this, the future focus should be on the standardization of herbal extracts, and further research is required to investigate the pharmacological mechanisms. Clinical research in this area remains in its infancy and warrants more robust further clinical studies.
Adsorption auf der ACHEMA 2022
Authors: Bläker Christian , Roehnert Mats , van Kessel Nils , Steinhaus Julian , Mauer Volker , Bathen Dieter 
Published: January 2023

AbstractNach einer längeren pandemiebedingten Pause fand 2022 in Frankfurt wieder die ACHEMA statt, auf der sich auch zahlreiche Firmen aus dem Bereich Adsorption präsentierten. Das weit gefächerte Ausstellerfeld reichte von Adsorbentienherstellern über Messgeräteentwickler bis hin zu Anlagenbauern. Der Bericht umfasst Trends und Neuerungen aus der Adsorptionstechnik, die auf den Ständen präsentiert und in Gesprächen mit den Ausstellern thematisiert wurden.
Electronic Modulation and Mechanistic Study of Ru‐Decorated Porous Cu‐Rich Cuprous Oxide for Robust Alkaline Hydrogen Oxidation and Evolution Reactions
Authors: Liu Yi , Cheng Lianrui , Huang Yi , Yang Yuting , Rao Xianfa , Zhou Shuqing , Taylor Isimjan Tayirjan , Yang Xiulin 
Published: January 2023

AbstractRational design of high‐efficiency and viable electrocatalysts is essential in overcoming the bottleneck of sluggish alkaline hydrogen oxidation/evolution reaction (HOR/HER) kinetics. In this study, a metal‐organic framework‐derived strategy for constructing a Pt‐free catalyst with Ru clusters anchored on porous Cu−Cu2O@C is proposed. The designed Ru/Cu−Cu2O@C exhibits superior HOR performance, with a mass activity of 2.7 mA
at 50 mV, which is about 24 times higher than that of state‐of‐the‐art Pt/C (0.11 mA
). Significantly, Ru/Cu−Cu2O@C also displays impressive HER performance by generating 26 mV at 10 mA cm−2, which exceeds the majority of documented Ru‐based electrocatalysts. Systematic characterization and density functional theory (DFT) calculations reveal that efficient electron transfer between Ru and Cu species results in an attenuated hydrogen binding energy (HBE) of Ru and an enhanced hydroxy binding energy (OHBE) of Cu2O, together with an optimized H2O adsorption energy with Cu2O as the H2O*‐capturing site, which jointly facilitates HOR and HER kinetics.
Estimating total species richness: Fitting rarefaction by asymptotic approximation
Authors: Zou Yi , Zhao Peng , Axmacher Jan Christoph 
Published: January 2023

AbstractEstimating the number of species in a community is important for assessments of biodiversity. Previous species richness estimators are mainly based on nonparametric approaches. Although parametric asymptotic models have been applied, they received limited attention due to specific limitations. Here, we introduce parametric models fitting the probability‐based rarefied species richness curve that allow us to estimate the “Total Expected Species” (TES) in a community based on species' abundance data. We develop two approaches to calculate TES (termed “TESa” and “TESb”), based on two slightly different mathematical assumptions regarding Expected Species (ES) models. We provide R functions to calculate both these estimation approaches and their standard deviation. The function also enables users to visualize the estimation. We test the performance of TESa, TESb, and their average (TESab) across simulated and empirical data, and compare their bias, precision, and accuracy with other commonly used, nonparametric species richness estimators: the bias‐corrected (bc‐)Chao1 and the abundance‐based coverage estimator (ACE). Simulation reveals that in small samples TESa shows a tendency to overestimate and TESb to underestimate overall species richness. TESab performs well in bias, precision, and accuracy when compared with (bc‐)Chao1 and ACE estimators. Results from empirical data show that the variance generated from TES estimates is comparable with that for (bc‐)Chao1 and ACE. Our study demonstrates that rarefaction theory in combination with parametric approximation models provides a valuable new approach to estimate the species richness of incompletely sampled communities. Robust estimates are likely to be obtained where the observed number of species is greater than half of the TES estimation. When the ratio of TESa to the observed richness is ≫2, we suggest the use of TESb or TESab. Although more comprehensive comparisons with other estimators are suggested, we encourage researchers to consider the TES approach in their biodiversity studies as a complement to current existing estimators.
Sulfur Monoxide Release and Capture: A Computational Study
Authors: Idzko Paul , Wagner J. Philipp 
Published: January 2023

AbstractThermolysis of thiirane oxide leads to production of highly reactive sulfur monoxide. The liberated SO can in turn be trapped with a diene scavenger forming dihydrothiophene oxide. Since the intermediate diatomic possesses a triplet ground state, the SO transfer can proceed on two spin‐state surfaces. Here, we study the competition between singlet concerted and stepwise triplet diradical mechanisms utilizing the M06‐2X density functional as well as CCSD(T) and MRCI+Q wavefunction theories. We find that the decomposition of thiirane oxide prefers to pass through a triplet diradical intermediate that becomes accessible from a nearby minimum energy crossing point (MECP). Hence, the thermolysis of thiirane oxide is expected to predominantly release triplet ground state sulfur monoxide in agreement with previous experimental reports. The addition of 3SO to 1,3‐butadiene initially generates an allylic diradical, that ring‐closes to a thiirane oxide through another MECP, and a subsequent rearrangement gives access to the final product.
Nucleophilicities of Cyclic α‐Diazo Carbonyl Compounds
Authors: Li Le , Hsu Jer‐Ray , Zhao Hongqing , Ofial Armin R. 
Published: January 2023

AbstractThe one‐bond nucleophilic reactivities of seven cyclic α‐diazo carbonyl compounds in dichloromethane were determined by analyzing the kinetics of their reactions with benzhydrylium ions (one‐bond reference electrophiles) at 20 °C according to the Mayr‐Patz equation. Though not calibrated for pericyclic reactions, the identified nucleophilicities also reflect relative reactivities of the α‐diazo carbonyl compounds in 1,3‐dipolar cycloadditions with dimethyl acetylenedicarboxylate. These (3+2)‐cycloadditions primarily gave spirocyclic 3H‐pyrazoles, which underwent thermal [1,5]‐sigmatropic (van Alphen‐Hüttel) rearrangements to furnish 1H‐pyrazole‐fused tricyclic products.
Evaluating the Protectiveness of a Bioavailability-Based Environmental Quality Standard for the Protection of Aquatic Communities from Zinc Toxicity Based on Field Evidence
Authors: Peters Adam , Wilson Iain , Cooper Christopher A. , Ryan Adam , Van Assche Frank , Winbow Howard 
Published: January 2023

Abstract
Environmental quality standards (EQS) are typically derived from the results of laboratory studies on single species. There is always uncertainty surrounding the protectiveness of an EQS when applied to real ecosystems containing a multitude of chemical and physical stressors. Quantile regression was used with field biological data on invertebrates in United Kingdom waters to identify taxa that are responsive to bioavailable zinc exposures. A threshold based on the total abundance of eight responsive taxa is used as an indicator of the overall ecosystem sensitivity. The inclusion of some responsive but insensitive taxa in this ecological metric could bias the results toward a higher threshold. The least responsive species were progressively removed from the collective ecological metric, basing the analysis on a progressively smaller number of the more responsive species. Quantile regression analysis at the 95th quantile for the three most responsive taxa resulted in a 10% effect concentration of 14.8 µg L−1 bioavailable zinc, suggesting that the EQS of 10.9 µg L−1 bioavailable zinc is sufficiently protective of sensitive members of the invertebrate community. There is a compromise between the robustness of the analysis and the sensitivity of the subcommunity that it is based on. Analyses based on fewer taxa provide a more sensitive result. This approach assessed real ecosystem data and evaluated the uncertainty associated with the protectiveness of the EQS for zinc. The zinc EQS is sufficiently protective of sensitive members of benthic macroinvertebrate communities under real environmental conditions, including a mix of multiple substances. Environ Toxicol Chem 2023;42:1010–1021. © 2023 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC.
Advances in forecasting: An introduction in light of the debate on inflation forecasting
Authors: Banerjee Anindya , Hall Stephen G. , Kouretas Georgios P. , Tavlas George S. 
Published: January 2023

AbstractThe sharp rise in inflation during the past few years has engendered comparisons with the great inflation of the 1970s and early 1980s. Like that earlier episode, the recent inflation has been underpinned by supply‐side shocks and, in the case of the United States, by highly accommodative fiscal and monetary policies. Like that early episode, the recent inflation has been largely unpredicted; it caught US policy makers by surprise, despite the fact that several prominent economists had warned early on that fiscal and monetary policies were setting the stage for an upsurge in inflation. To motivate this special issue, we provide a brief account of the policy miscues and policy debates that resulted from the large forecast errors in predicting the upsurge in inflation in 2021 and 2022. We then provide an overview of the papers in this issue, which address a range of methodological and empirical issues related to forecasting and highlight the dilemmas faced by agents within the economy and policy makers.
A tale of two premiums revisited
Authors: Maréchal Loïc 
Published: January 2023

AbstractThis paper investigates the effect of the “financialization” of commodity markets in terms of pricing. I explore whether the emergence of commodity index traders (CITs) affects weekly returns and turnover during the roll periods. I split the sample (1994–2017) into prefinancialization (1994–2003) and postfinancialization (2004–2017). I directly test whether the CIT market share (CIT/open interest) contributes to commodity returns and whether risk adjustments (based on momentum, basis, basis‐momentum, open interest, crowding, and average factors) alter liquidity and insurance premiums documented in Kang, Rouwenhorst, and Tang. I also examine how the financialization affects liquidity and insurance premiums. Finally, since previous results are obtained with Fama–MacBeth regressions, I use an alternative method to test how liquidity and insurance premiums determine commodity returns.