bluuebunny/crossref_metadata_2025_split huggingface dataset:
Application of Artificial Intelligence on Predicting the Effects of Buoyancy Ratio on Magnetohydrodynamics Double-Diffusive Mixed Convection and Entropy Generation in Different Nanofluids and Hybrid Nanofluids
Authors: Prince Hasib Ahmed , Siam Md Mehrab Hossen , Ghosh Amit , Mamun Mohammad Arif Hasan 
Published: May 2023

Abstract
The present computational investigation aims to investigate the effect of varied buoyancy ratios on mixed convection and entropy formation in a lid-driven trapezoidal enclosure under magnetic field with two rotating cylinders. The effects of SWCNT–water, Cu–water, and Al2O3–water nanofluids individually, as well as effects of three different types of SWCNT–Cu–Al2O3–water hybrid nanofluids are examined. The governing Navier–Stokes, thermal energy, and mass conservation equations are solved using the Galerkin weighted residual finite element method to obtain results as average Nusselt number, Sherwood number, temperature, and Bejan number as output parameters inside the enclosure for different parameter values. Then, an innovative artificial neural network model for effective prediction is created using the simulation data. The optimum values of each of these input parameters are obtained by finite element method (FEM) and artificial neural network (ANN), and a comparative study between FEM and ANN is done to get best results for the output parameters. The performance of the created ANN model for novel scenarios is evaluated using Cu–Al2O3–water hybrid nanofluid. The proposed innovative ANN model predicts the findings with less time and sufficient accuracy for each type of studied governing fluids. The model’s accuracy for predicting convective heat and mass transfer, along with average dimensionless temperature and Bejan number, was 96.81% and 98.74%, respectively, when tested on training and validation data. On test data, the accuracy was 97.03% for convective heat and mass transfer and 99.17% for average dimensionless temperature and Bejan number.
Northern Sierra Nevada, California: Ophiolites, metamorphic soles, and blueschists to active tectonics and geomorphology
Authors: Wakabayashi John , Shimabukuro David , Masutsubo Nobuaki , Eck Dennis , Spencer Sean , Kemp Chris , Inman Adam , Luo Jun , Smart Chris , Sanborn Erica 
Published: May 2023

1. ABSTRACTThe geology of the northern Sierra Nevada of California records &gt;400 million years of active plate margin tectonic events as a part of the North American Cordilleran orogenic belt. This field-trip guide provides geologic background and description of field-trip stops for a two-day field trip of the 2023 Geological Society of America Cordilleran Section Meeting based in Reno, Nevada. In two days, we cannot sample the complete geologic record of the northern Sierra Nevada, so this guide does not provide an exhaustive review of this geology. We will focus on certain aspects of the geology that have been the subject of recent research and present some previously unpublished observations and interpretations including: (1) distinguishing between subduction complexes and deformed assemblages that overlay subduction zones; (2) evidence for subduction initiation, recorded in high-pressure (P), high-temperature (T) amphibolites and possibly greenschist facies rocks structurally beneath them; (3) finding of high-P, high-T amphibolite blocks in mélange zones in subduction complex units accreted structurally beneath intact high-P, high-T amphibolite horizons; (4) differences in stream profiles between southern Cascade and northern Sierra drainages, suggesting different forcing mechanisms for stream erosion in those regions; and (5) complex relationships between stream incision, volcanic deposition, and Late Cenozoic faulting.• DEDICATION •This field–trip guide is dedicated to Eldridge Moores (1938–2018) and Jason Saleeby (1948–2023) who were giants in Sierra Nevada geologic research. Eldridge passed away in October 2018 while leading a field trip in this area on which the leaders of the current field trip (JW, DS) were participants. Jason passed away during the writing of this guide. As will be clear from reading this guide, the saying “standing on the shoulders of giants” applies.
The Chiral Spin-Orbitronics of a Helimagnet–Normal Metal Heterojunction
Authors: Ustinov V. V. , Yasyulevich I. A. , Bebenin N. G. 
Published: May 2023

Abstract
A theory of spin and charge transport in bounded metallic magnets has been constructed, which takes into account the effects of spin-orbit scattering of conduction electrons by crystal lattice defects. The theory can be used to describe the spin Hall effect and the anomalous Hall effect and can serve as a basis for describing the phenomena of spin-orbitronics. Phenomenological boundary conditions for the charge and spin fluxes at the interface between two different metals have been formulated, on the basis of which the injection of a pure spin current into a helimagnet, which arises in a normal metal as a manifestation of the spin Hall effect, is described. The existence of an “effect of chiral polarization of a pure spin current” is predicted, which consists in the appearance in a helimagnet of a longitudinally polarized pure spin current and a longitudinal component of the nonequilibrium electron magnetization, depending on the chirality of the helimagnet helix, upon injection of a transversely polarized spin current from a normal metal.
Pyogenic granuloma of the epiglottis: a common lesion in a rare site
Authors: Franco Helena , Slee Nicola 
Published: May 2023

Pyogenic granulomas are benign vascular lesions occurring on skin and mucous membranes, most commonly in the oral cavity.A case report of a woman in her 80s who presented with one episode of haemoptysis, secondary to an atypical epiglottic lesion is discussed. The patient denied associated symptoms, such as dyspnoea, dysphasia or recent weight loss. Flexible nasendoscopy and CT scan confirmed a highly vascular pedunculated mass on the left laryngeal surface of the epiglottis. The lesion was completely excised and there was no sign of recurrence after a 12-month follow-up.This case report represents the fourth documented case of a pyogenic granuloma arising from the epiglottis, resulting in haemoptysis. While rare, there is a significant risk of airway compromise from haemorrhage, which is refractory to pressure and may be difficult to control at this site. Surgery is required to completely excise the lesion and prevent recurrence.
Turnover intention among healthcare workers in Ethiopia: a systematic review and meta-analysis
Authors: Gebrekidan Amanuel Yosef , Enaro Eskindir Yilma , Azeze Gedion , Adella Getachew Asmare , Kassie Gizachew Ambaw , Haile Kirubel Eshetu , Asgedom Yordanos Sisay 
Published: May 2023

ObjectiveTo determine the pooled prevalence of turnover intention among healthcare workers in Ethiopia.DesignA systematic review and meta-analysis was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline.Data sourcesElectronic databases of Science Direct, Medline, African Journals Online, Excerpta Medica Database, Scopus and Google Scholar were searched to identify studies published in the English language before 31 December, 2021.Eligibility criteriaStudies were included with following criteria: (1) studies conducted or published until 31 December 2021; (2) observational studies; (3) Studies conducted on healthcare workers; (4) reporting turnover intention; (v) studies conducted in Ethiopia and (vi) tudies published in the English language were included.Data extraction and synthesisThree independent reviewers screened all the papers for eligibility criteria. Data were extracted by two independent investigators using a standardised data extraction format. Random effects model meta-analysis using STATA V.14.0 statistical software was conducted to estimate the pooled prevalence of turnover intention with 95% CI. Funnel plot and Forest plot were used to check publication bias and heterogeneity between studies, respectively. Leave-one-out sensitivity analysis was done.Primary outcomePrevalence of turnover intention.ResultA total of 29 cross-sectional studies with 9422 participants met the inclusion criteria. The estimated pooled prevalence of turnover intention among healthcare workers in Ethiopia was 58.09% (95% CI 54.24 to 61.93; p value <0.001, I2=93.5%).ConclusionThe finding of this systematic review and meta-analysis showed high prevalence of turnover intention among healthcare workers in Ethiopia. The Government and policy makers should come up with different mechanisms including a wide variety of healthcare workers retention strategies in order to reduce turnover intention of healthcare workers and retain them.
Value in psoriasis (IRIS) trial: implementing value-based healthcare in psoriasis management – a 1-year prospective clinical study to evaluate feasibility and value creation
Authors: Hilhorst Niels , Roman Erin , Borzée Joke , Deprez Elfie , Hoorens Isabelle , Cardoen Brecht , Roodhooft Filip , Lambert Jo 
Published: May 2023

IntroductionCurrently, the healthcare sector is under tremendous financial pressure, and many acknowledge that a dramatic shift is required as the current system is not sustainable. Furthermore, the quality of care that is delivered varies strongly. Several solutions have been proposed of which the conceptual framework known as value-based healthcare (VBHC) is further explored in this study for psoriasis. Psoriasis is a chronic inflammatory skin disease, which is associated with a high disease burden and high treatment costs. The objective of this study is to investigate the feasibility of using the VBHC framework for the management of psoriasis.Methods and analysisThis is a prospective clinical study in which new patients attending the psoriasis clinic (PsoPlus) of the Ghent University Hospital will be followed up during a period of 1 year. The main outcome is to determine the value created for psoriasis patients. The created value will be considered as a reflection of the evolution of the value score (ie, the weighted outputs (outcomes) divided by weighted inputs (costs)) obtained using data envelopment analysis. Secondary outcomes are related to comorbidity control, outcome evolution and treatment costs. In addition, a bundled payment scheme will be determined as well as potential improvements in the treatment process. A total of 350 patients will be included in this trial and the study initiation is foreseen on 1 March 2023.Ethics and disseminationThis study has been approved by the Ethics Committee of the Ghent University Hospital. The findings of this study will be disseminated by various means: (1) publication in one or more peer-reviewed dermatology and/or management journals, (2) (inter)national congresses, (3) via the psoriasis patient community and (4) through the research team’s social media channels.Trial registration numberNCT05480917.
Organisational commitment, job satisfaction and intention to leave among physicians in the public health sector of Cyprus: a cross-sectional survey
Authors: Gregoriou Ioanna , Papastavrou Evridiki , Charalambous Andreas , Economidou Eleftheria , Soteriades Elpidoforos Soterakis , Merkouris Anastasios 
Published: May 2023

ObjectivesOrganisational commitment, job satisfaction and intention to leave constitute important characteristics of health professionals’ employment status. Our study aimed at investigating the level of organisational commitment, job satisfaction in association with intention to leave among physicians.DesignA cross-sectional study.SettingA survey was conducted using self-administered questionnaires (the Organizational Commitment Questionnaire and the Job Satisfaction Survey) among all physicians working in the public health sector of Cyprus (October 2016–January 2017).ParticipantsOut of 690 physicians working in the public health sector who received an invitation to participate, 511 completed the survey and 9 were excluded. Therefore, 502 physicians were included in the final analysis (response rate 73%). A total of 188 cases were excluded because they were undetermined with respect to their intention to leave and a total of 75 cases were excluded from the regression analysis due to missing values on at least one variable or due to having values considered as outliers. Therefore, a total of 239 physicians (120 men and 119 women) were included in the current analysis.Primary and secondary outcome measuresPhysicians’ intention to leave.ResultsA considerably large percentage of physicians (72.8%) working in the public hospitals and healthcare centres of Cyprus reported their intention to leave their job. Moreover, the majority of employees in public hospitals (78.4%) intended to leave their job, while only 21.6% of employees in health centres reported an intention to leave (p<0.001). The study also confirmed that organisational commitment and job satisfaction were negatively correlated with intention to leave. In addition, the results of this study demonstrate that certain demographics also influence physicians’ intention to leave including age, gender and medical specialisation.ConclusionsCertain physicians’ demographics, organisational commitment and job satisfaction constitute important parameters influencing physicians’ intention to leave their job.
Evaluating the implementation of the Mayo-Portland Adaptability Inventory-4 (MPAI-4) in three rehabilitation settings in Quebec: a mixed-methods study protocol
Authors: Kengne Talla Pascaline , Thomas Aliki , Ataman Rebecca , Auger Claudine , McKerral Michelle , Wittich Walter , Poncet Frédérique , Ahmed Sara 
Published: May 2023

IntroductionStroke is a leading cause of morbidity and mortality worldwide, placing an immense burden on patients and the health system. Timely access to rehabilitation services can improve stroke survivors’ quality of life. The use of standardised outcome measures is endorsed for optimising patient rehabilitation outcomes and improving clinical decision-making. This project results from a provincially mandated recommendation to use the fourth version of the Mayo-Portland Adaptability Inventory (MPAI-4) to measure changes in social participation of stroke survivors and to maintain commitment to evidence-informed practices in stroke care. This protocol outlines the implementation process of the MPAI-4 for three rehabilitation centres. The objectives are to: (a) describe the context of MPAI-4 implementation; (b) determine clinical teams’ readiness for change; (c) identify barriers and enablers to implementing the MPAI-4 and match the implementation strategies; (d) evaluate the MPAI-4 implementation outcomes including the degree of integration of the MPAI-4 into clinical practice and (e) explore participants’ experiences using the MPAI-4.Methods and analysisWe will use a multiple case study design within an integrated knowledge translation (iKT) approach with active engagement from key informants. Each case is a rehabilitation centre implementing MPAI-4. We will collect data from clinicians and programme managers using mixed methods guided by several theoretical frameworks. Data sources include surveys, focus groups and patient charts. We will conduct descriptive, correlational and content analyses. Ultimately, we will analyse, integrate data from qualitative and quantitative components and report them within and across participating sites. Results will provide insights about iKT within stroke rehabilitation settings that could be applied to future research projects.Ethics and disseminationThe project received Institutional Review Board approval from the Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal. We will disseminate results in peer-reviewed publications and at local, national and international scientific conferences.
Effect of rectus sheath anaesthesia versus thoracic epidural analgesia on postoperative recovery quality after elective open abdominal surgery in a French regional hospital: the study protocol of a randomised controlled QoR-RECT-CATH trial
Authors: Maury Thomas , Elnar Arpiné , Marchionni Sandra , Frisoni Romain , Goetz Christophe , Bécret Antoine 
Published: May 2023

IntroductionEnhanced recovery after surgery (ERAS) protocols increase patient well-being while significantly reducing mortality, costs and length-of-stay after surgery. A key component is multimodal analgesia that prevents postoperative pain and facilitates early refeeding and mobilisation. Thoracic epidural analgesia (TEA) was long the gold standard for locoregional anaesthesia in anterior abdominal wall surgery. However, newer wall-block techniques such as rectus-sheath block (RSB) may be preferable because they are less invasive and may provide equivalent analgesia with fewer side effects. Since the evidence base remains limited, the Quality Of Recovery enhanced by REctus sheat CATHeter (QoR-RECT-CATH) randomised controlled trial (RCT) was designed to assess whether RSB elicits better postoperative rehabilitation than TEA after laparotomy.Methods and analysisThis open-label parallel-arm 1:1-allocated RCT will determine whether RSB is superior to TEA in 110 patients undergoing scheduled midline laparotomy in terms of postoperative rehabilitation quality. The setting is a regional French hospital that provides opioid-free anaesthesia for all laparotomies within an ERAS programme. Recruited patients will be ≥18 years, scheduled to undergo laparotomy, have American Society of Anesthesiologists (ASA) score 1–4 and lack contraindications to ropivacaine/TEA. TEA-allocated patients will receive an epidural catheter before surgery while RSB-allocated patients will receive rectus sheath catheters after surgery. All other pre/peri/postoperative procedures will be identical, including multimodal postoperative analgesia provided according to our standard of care. Primary objective is a change in total Quality-of-Recovery-15 French-language (QoR-15F) score on postoperative day (POD) 2 relative to baseline. QoR-15F is a patient-reported outcome measure that is commonly used to measure ERAS outcomes. The 15 secondary objectives include postoperative pain scores, opioid consumption, functional recovery measures and adverse events.Ethics and disseminationThe French Ethics Committee (Sud-Ouest et Outre-Mer I Ethical Committee) gave approval. Subjects are recruited after providing written consent after receiving the information provided by the investigator. The results of this study will be made public through peer-reviewed publication and, if possible, conference publications.Trial registration numberNCT04985695.
Hospital readmissions and mortality following discharge against medical advice: a five-year retrospective, population-based cohort study in Veneto region, Northeast Italy
Authors: Saia Mario , Salmaso Laura , Bellio Stefania , Miatton Andrea , Cocchio Silvia , Baldovin Tatjana , Baldo Vincenzo , Buja Alessandra 
Published: May 2023

ObjectivesThe aim of this study was to examine the odds of readmission and mortality after discharge against medical advice (DAMA) in the Veneto region of Northeast Italy, drawing on data from the regional archives of emergency department records and hospital discharge records.DesignA retrospective cohort study.SettingHospital discharges, Veneto region, Italy.ParticipantsAll patients discharged after being admitted to a public or accredited private hospital between January 2016 and 31 January 2021 in the Veneto region were considered. A total of 3 574 124 index discharges were examined for inclusion in the analysis.Primary and secondary outcome measuresReadmission and overall mortality at 30 days after the index discharge against admission.ResultsIn our cohort, 7.6‰ of patients left hospital against their doctor’s advice (n=19 272). These DAMA patients were more likely to be younger (mean age: 45.5 vs 55.0), foreign (22.1% vs 9.1%). The adjusted odds of readmission after DAMA was 2.76 (CI 95% 2.62–2.90) at 30 days (9.5% DAMA vs 4.6% not-DAMA), and the highest readmission rate was recorded in the first 24 hours after the index discharge. Mortality was higher for DAMA patients after adjusting for patient-level and hospital-level characteristics (with adjusted ORs of 1.40 for in-hospital mortality and 1.48 for overall mortality).ConclusionsThe present study shows that DAMA patients are more likely to die and to need hospital readmission than patients discharged by their doctors. DAMA patients should be more committed to a proactive and diligent postdischarge care.
Neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene orMYCNgene
Authors: Bhardwaj Neha , Das Gargi , Srinivasan Radhika 
Published: May 2023

TheMYCNgene belongs to the MYC family of transcription factors. Amplification ofMYCN, first discovered in neuroblastoma cells, ushered in the era of cancer genomics. TheMYCNgene and MYCN protein are extensively studied in the context of neuroblastoma. As demonstrated in transgenic mouse models,MYCNgene shows a restricted spatiotemporal expression predominantly in the neural crest cells which explains the associated neoplasms including neuroblastoma and central nervous system tumours. In neuroblastoma,MYCNamplification is a marker of aggressive tumours with poor prognosis and survival and forms the basis of risk stratification classifications.MYCNdysregulated expression occurs by several mechanisms at the transcriptional, translational and post-translational levels. These include massive gene amplification which occurs in an extrachromosomal location, upregulated transcription and stabilisation of the protein increasing its half-life. MYCN protein, a basic loop-helix-loop leucine zipper transcription factor, has many regions which bind to several proteins foremost of which is MAX forming the MYC:MAX heterodimer. Overall, MYCN controls multiple aspects of cell fate, foremost of which is cellular proliferation besides cell differentiation, apoptosis and cellular metabolism, all of which are the focus of this brief review. In addition to amplification, other mechanisms of MYCN overexpression include activating missense mutations as reported in basal cell carcinoma and Wilms tumour. A better understanding of this molecule will help in the discovery of novel strategies for its indirect targeting to improve the outcomes of patients with neuroblastoma and other MYCN-associated neoplasms.