bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using telemedicine to manage a patient with a hypertensive emergency due to pheochromocytoma
Authors: Konishi Seigo , Kometani Mitsuhiro , Aiga Ko , Aono Daisuke , Nohara Takahiro , Ikeda Hiroko , Karashima Shigehiro , Takeda Yoshiyu , Yoneda Takashi 
Published: July 2023

Summary
The COVID-19 pandemic has led to the emergence of telemedicine on a global scale. In endocrinology, telemedicine has mainly been used in relation to chronic diseases, including diabetes. Herein, we report the case of an 18-year-old woman with a hypertensive emergency due to a pheochromocytoma who was quickly diagnosed and treated using telemedicine. The patient was referred to a cardiovascular hospital because of fatigue and sweating that did not improve with carvedilol. She had fluctuating blood pressure and tachycardia. Subsequently, since her thyroid function was normal, endocrine hypertension not due to thyroid dysfunction was suspected; a case consultation was made by phone to our clinic. Plain computed tomography (CT) was recommended owing to the high possibility of a pheochromocytoma; the CT scan showed an adrenal tumor with a 30 mm diameter. To assess her condition, endocrinologists, together with the attending doctor, interviewed her and her family directly using an online tool to obtain detailed information. We thus determined that she was at risk of a pheochromocytoma crisis. She was transferred to our hospital immediately for treatment, was diagnosed with pheochromocytoma, and underwent surgery. Telemedicine, especially involving doctor-to-patient with doctor consultations, can be effective in treating rare and emergent medical conditions such as pheochromocytoma crisis.

Learning points

Telemedicine can be used for chronic diseases and emergency conditions.

Online doctor-to-patient with doctor (D-to-P with D) consultations are useful when the expert opinion of a highly specialized physician present in a different geographical location is required.

Telemedicine, especially D-to-P with D online consultations, can be effectively used for the diagnosis of rare and emergent medical conditions, such as pheochromocytoma crisis.
Common Data Element Collection in Underserved School Communities: Challenges and Recommendations
Authors: Uthappa Diya M. , Mann Tara K. , Goldman Jennifer L. , Schuster Jennifer E. , Newland Jason G. , Anderson William B. , Dozier Ann , Inkelas Moira , Foxe John J. , Gwynn Lisa , Gurnett Christina A. , McDaniels-Davidson Corinne , Walsh Tyler , Watterson Tremayne , Holden-Wiltse Jeanne , Potts Jessie M. , D’Agostino Emily M. , Zandi Karen , Corbett Anthony , Spallina Samantha , DeMuri Gregory P. , Wu Yelena P. , Pulgaron Elizabeth R. , Kiene Susan M. , Oren Eyal , Allison-Burbank Joshuaa D. , Okihiro May , Lee Rebecca E. , Johnson Sara B. , Stump Tammy K. , Coller Ryan J. , Mast Dana Keener , Haroz Emily E. , Kemp Steven , Benjamin Daniel K. , Zimmerman Kanecia O. 
Published: July 2023

OBJECTIVES
To provide recommendations for future common data element (CDE) development and collection that increases community partnership, harmonizes data interpretation, and continues to reduce barriers of mistrust between researchers and underserved communities.

METHODS
We conducted a cross-sectional qualitative and quantitative evaluation of mandatory CDE collection among Rapid Acceleration of Diagnostics-Underserved Populations Return to School project teams with various priority populations and geographic locations in the United States to: (1) compare racial and ethnic representativeness of participants completing CDE questions relative to participants enrolled in project-level testing initiatives and (2) identify the amount of missing CDE data by CDE domain. Additionally, we conducted analyses stratified by aim-level variables characterizing CDE collection strategies.

RESULTS
There were 15 study aims reported across the 13 participating Return to School projects, of which 7 (47%) were structured so that CDEs were fully uncoupled from the testing initiative, 4 (27%) were fully coupled, and 4 (27%) were partially coupled. In 9 (60%) study aims, participant incentives were provided in the form of monetary compensation. Most project teams modified CDE questions (8/13; 62%) to fit their population. Across all 13 projects, there was minimal variation in the racial and ethnic distribution of CDE survey participants from those who participated in testing; however, fully uncoupling CDE questions from testing increased the proportion of Black and Hispanic individuals participating in both initiatives.

CONCLUSIONS
Collaboration with underrepresented populations from the early study design process may improve interest and participation in CDE collection efforts.
Retos laborales en el bicentenario de la independencia costarricense
Authors: Briones Eric Briones 
Published: July 2023

El presente ensayo, recoge el análisis jurídico en torno a algunos retos que considera el autor, son los más relevantes dentro del ámbito laboral a nivel nacional, de cara al bicentenario que celebra el país, desde su independencia; en él se analiza un aparte histórico jurídico y algunos institutos del derecho laboral (nuevas figuras contractuales, adaptabilidad de las jornadas, un paradigma distinto del cuerpo inspectivo, etc), que deben ser remozados, actualizados o incluidos, dentro de una norma general, tanto sector público como privado, que venga a unificar, la normativa dispersa, la cual en muchos casos, ni siquiera se sabe de su existencia, debido a la falta de sistematización en un solo cuerpo, dentro del principio de seguridad jurídica.
Sirva el presente para constituirse en un primer escenario de partida, para lo que posteriormente, deba repensarse como nación.
Reflexiones sobre inteligencia artificial y derecho
Authors: Sánchez Jesús Abarca 
Published: July 2023

La Inteligencia Artificial (IA) se presenta como una tecnología protagonista en los avances que se están dando en el contexto de la Revolución Industrial 4.0. Es necesario que el jurista reflexione sobre sus efectos en el mundo jurídico. En esta ocasión se partirá de un análisis relativo a la IA, en relación a sus usos cotidianos en la praxis jurídica en su función como asistente legal, y, luego en lo que respecta a sus desafíos éticos que implica su actualidad y evolución inminente.
The Application of Fiqh Principles in Contemporary Sharia Transactions in The Development of Innovative Products of Islamic Financial Institutions in Indonesia
Authors: ‘Ilmi Zujajatul 
Published: July 2023

The innovation product in Islamic financial institutions is one of the strategies that has an important role in the midst of a competitive market. Increasing institutional capacity and the availability of diverse and efficient Islamic financial industry products is one of the missions in optimizing the development of Islamic finance. The program to increase the availability and diversity of Islamic financial types available in various products, in Islamic banking institutions and non-Islamic bank financial institutions, including the Islamic capital market, shows that the market share of Islamic financial industry products is still limited when compared to conventional financial products. In Indonesia, all stakeholders of the Islamic financial industry must always synergize and harmonize between sharia economic law and applicable laws and regulations. The Qur'an, Al-Hadith and Ijma' gave birth to the rules of fiqh. The rules of fiqh aim to establish Islamic law in various issues that are new and continue to develop along with the times, especially developments in sharia financial institutions in various kinds of economic transactions or muamalah maliyah. The rules of fiqh are a form of ijtihad. The rule of fiqh is an ease of knowing contemporary laws, especially various kinds of economic problems that do not have much nash sharih (definite postulates) in the Qur'an and al-Hadith. In economic problems that develop in Islamic financial institutions, the rules of fiqh are used to facilitate mastering the problems of furu'iyyah (branches) which are many (countless) and continue to grow
HUMANITARIAN FOUNDATIONS OF THE CONTENT OF EDUCATION AT RIGA CLASSICAL GYMNASIUM IN THE CONTEXT OF THE “EUROPEAN DIMENSION IN EDUCATION”
Authors: Aliyev Roman , Chehlova Zoja , Chehlov Mikhail , Keviša Ingrīda 
Published: July 2023

In the 21st century, humankind has realised that the future of civilization is related to the development of education. A person capable of acquiring knowledge and applying it creatively, as well as being able to participate in the process of creating and using new knowledge, can only be prepared by an effective future-oriented system of education. Novelty of the research refers to the development of the structure of the content of education in the gymnasium as the relationship between didactics (knowledge and skills) and culture. Culture is viewed as the interconnection of three cultures: social experience (universal human values), the culture of a student, and the culture of a teacher. Research problem is the determination of the essence and structure of the content of education in the gymnasium in accordance with the new humanitarian paradigm of education as the relationship between didactics and culture, the basis for the development of student’s personality. The aim of the research is to analyse the humanitarian foundations of the content of education in the gymnasium in the context of the “European dimension in education”. The research method is theoretical analysis. The results of the research are as follows: the humanitarian foundations of the content of education in the gymnasium have been determined; the essence and structure of the content of education have been elaborated. On this basis, an effective system of profile education has been created for the development of student’s personality as a future professional and a European citizen having moral values. The present study leads to the conclusion that the humanitarian foundations in the content of education correspond to the “European dimension in education”.
ANTHROPOLOGICAL IDEAS OF MYKOLA SHLEMKEVICH AS THE FUNDAMENTAL SUBSTITUTE FOR THE FORMATION OF THE NATIONAL CONSCIOUSNESS OF UKRAINIANS
Authors: Skotna Nadia , Ashytok Nadiya , Hirnyak Svitlana , Kutnyak Ivan , Yatsiv Oksana , Klym Maryana 
Published: July 2023

The events of the last decade (the Orange Revolution, the Revolution of Dignity, the Russian-Ukrainian war) actualized the problem of the formation of the national self-awareness of Ukrainians. This process has accelerated significantly and acquired more expressive outlines. Therefore, in response to modern challenges, pedagogues intensified the research of the specified problem, based not only on the latest achievements of the human sciences, but also referring to historical experience. Based on the analysis of the Mykola Shlemkevych’ works (Shlemkevych, 1956; Shlemkevych, 1958; Shlemkevych, 1961; Shlemkevych, 1962; Shlemkevych, 1992a; Shlemkevych, 1992b), the article deals with his anthropological ideas, substantiates the fundamental basis of the formation of the national consciousness of Ukrainians, defines ideas related to the idea of a person as a bearer of good and evil. In the formation of national consciousness, anthropological ideas are taken into account, that form the basis of this formation. It is about the humanistic principles of the formation of the national consciousness of Ukrainians, which determine the reliance on spiritual and moral values. Mykola Shlemkevych paid great attention to anthropological ideas related to the national consciousness of Ukrainians. Emphasis on the ideals of good in the mind of a person does not mean the absence of evil intentions. However, he always insisted on the need to forgive people for their sins, which accompany the defense of their national interests and the protection of national rights. Today, it seems extremely important to read the anthropological views of the teacher from the standpoint of today, which has become the goal of scientific research. As a result of the conducted research, we have come to the conclusion about the need for methodological substantiation and rethinking of the anthropological ideas of scientists P. Yurkevych (1999), K. Ushynskyi (1954), O. Vyshnevskyi (1996), etc., the need to build an educational paradigm based on anthropocentrism, democracy, humanism, determinism, it is defined the fundamental foundation of Ukrainian pedagogy as the reliance on theoretical and applied concepts of world and Ukrainian pedagogical thought.
POSSIBILITIES OF INCLUSION OF NEWCOMERS IN GENERAL SCHOOLS OF LATVIA
Authors: Danilāne Liga , Danilāne Lauma 
Published: July 2023

At the time when Russia is conducting military operations in Ukraine, Latvia provides all possible political, financial, military and humanitarian support to Ukraine, including hosting Ukrainian residents fleeing the war in Latvia. Education plays a vital role in the economic, social and cultural integration of migrants and refugees in the host country. Education is a key tool for transitioning from humanitarian to development and integrating those granted asylum into society. The aim of study: to study the possibilities and threats of inclusion of newcomers in general education schools and to analyze the experience of students included in general education schools of the city of Rēzekne and Rēzekne district.
TEACHER`S SOCIAL EMOTIONAL HEALTH AND RESILIENCE IN SLOVAKIA AND LATVIA DURING DISTANCE LEARNING SITUATION
Authors: Gajdošova Eva , Svence Guna 
Published: July 2023

The article brings the research results of the teachers´ social-emotional health and resilience in Slovak Republic and in Latvia during distance learning situation. The sample consisted of 800 teachers, 400 teachers from each country, who completed Social-Emotional Health Survey-Teachers (SEHS-T) and Resilience Scale (RS) during months of May through July 2021. The research results showed the highest covitality level of Slovak teachers in comparison with Latvian teachers (p ˂.001, r = .36). There was found a big difference in covitality in the clue domain Belief in Self in favour of Slovak teachers (p ˂.001; r = .44), there were only average differences in other domains - Belief in Others, Emotional Competence, Engaged Living. Latvian teachers reached high scores in cognitive reappraisal and optimism (p ˂.001). There was statistical difference in the level of resilience between Slovak and Latvian samples (p ˂.001; r = .35). Slovak teachers scored higher. But the teacher’s resilience in both countries had moderate level. Significant positive strong correlation was found between resilience and covitality in Slovak teachers rs = .76** and in Latvian teachers rs = .66**. Significant high and moderate positive correlations were found also between resilience and covitality domains.
VISUAL SEMIOTICS IN THE STUDY OF ART PHENOMENA: SYMBOL AND SYMPTOM
Authors: Senkāne Olga , Laganovska Karīne 
Published: July 2023

The study aims to use the approach of visual semiotics to analyse the ritual graphic signs of the Rezekne Jewish cemetery as a segment of the city in terms of "signifier" and "signified", or “expression” and “content”. The Star of David, as the dominant sign of the ritual graphics, is gradually losing the status of a sacred symbol and in a series of tombstones confirms the structure of a symptom. The paper is devoted not only to clarifying the cultural and social causes of such changes but also to the study of the mechanism of mutual transitions between symbols and symptoms, the differences in the coding of these types of signs, which has not been done in visual semiotics so far.Theoreticians have hitherto not paid due attention to the study of signs of graves as a segment of the urban environment. Moreover, the theory of visual semiotics also lacks a description of the specificity of signs in ritual graphics. Ritual graphics is an important indicator of the regularity of cultural processes in an ethnically diverse environment. When surveying the Jewish cemeteries of the Latgale region, the difference in the choice of visual graphics in the city and the countryside is obvious. In rural cemeteries that are still in use, the content and structure of verbal messages, as well as decorative graphics are traditional, therefore predictable. In city cemeteries, there is a change in graphics, deviations from tradition, its modification and obvious violations of tradition. Along with the verbal report about the deceased, the ritual graphic, on the one hand, complements it as an integral part, on the other hand, lives an independent life, because the first, and the only sign that the observer notices is the visual or non-verbal sign. In terms of information, the visual sign is noticeably more capacious, as it is older than the verbal and requires much less time for perception. The focus of the study is the divergence between the meanings of the sacred hexagram and the secular yellow star or “badge”, the causal relationships of their use and perception from the point of view of visual semiotics and cultural philosophy - phenomena of symbolization and desymbolization.
Exploring the therapeutic potential of phytoconstituents in treatment of polycystic ovarian syndrome: An study
Authors: Premkumar Balasekar , Priyanka Chandrasekar Leela , Nalini Calamur Nagarajan , Mahalakshmi  
Published: July 2023

Polycystic ovary syndrome (PCOS) is a prevalent condition among women of reproductive age, characterised by hyperinsulinemia, hyperandrogenism, menstrual irregularities, and long-term metabolic disturbances. At present, the conventional approach to managing PCOS involves implementing lifestyle changes, administering pharmacological interventions, and performing surgical procedures. Nevertheless, these therapies do not exhibit promising outcomes for the comprehensive eradication of it. Consequently, natural sources have been regarded as a highly esteemed means of medication and aid in enhancing and regulating PCOS conditions. The current study was designed to conduct a screening of various phytoconstituents with a focus on their potential interaction with androgenic targets (1E3G & 2PIV), estrogenic receptors (1U3S), and insulin receptors (3EKK). An assessment was conducted on a compilation of phytoconstituents documented in PCOS with the aim of forecasting drug-like characteristics through an methodology. Thirteen phytoconstituents were selected for the study, namely apigenin, berberine, erdosteine, colchicine, diacerin, mogroside V, naringenin, quercetin, resveratrol, rhamnocitrin, silibinin, tanshinone IIA, and troxerutin. The phytoconstituents were subjected to molecular docking studies using AutoDock Vina to investigate their binding interactions with proposed targets. Additionally, in silico prediction of the toxicity of these phytoconstituents was conducted. The phytoconstituents that were chosen exhibited favourable pharmacokinetic characteristics for oral bioavailability and drug-likeness, as determined by Lipinski's rule of five. As per the docking results, it was observed that four compounds, namely Apigenin, Tanshinone IIA, Naringenin, and Berberine, exhibited significant binding interactions with the allosteric site residues of the targets. The identified phytoconstituents that underwent screening exhibit potential as prospective candidates for subsequent development. However, it is imperative to validate the findings through in vitro and in vivo investigations.
Levobupivacaine versus ropivacaine in patients undergoing lower abdominal surgeries
Authors: Byndoor Yatish , Sagar Tamilisetti Vidya 
Published: July 2023

Regional anesthesia, like Peripheral nerve block, is commonly used for peripheral surgeries to reduce severe intraoperative and postoperative pain relief. .Some studies with levobupivacaine have shown that duration of analgesia of levobupivacaine are longer compared to that of an equivalent dose of bupivacaine or ropivacaine.This study is done to compare efficacy and safety of levobupivacaine with ropivacaine. In this study we tried to compare efficacy and clinical characteristics of isobaric forms of intrathecal levobupivacaine 0.5% and ropivacaine 0.75% in lower abdominal surgeries.This prospective, observational and open labeled, comparative study done for a period of one year in a tertiary care health centre, in South India, prior approval from Institutional ethics committee was taken. 60 patients were included and each of 60 patients was randomized (sealed, numbered and opaque envelopes) to one of two groups of 30 patients. Each of the patients enrolled in the study received one of two solutions: levobupivacaine or Ropivacaine, patient was turned supine immediately after injection, time of which was defined as ‘zero’. Thereafter, investigator, assessed upper and lower limits of sensory block (analgesia to pinprick), degree of motor block and recorded heart rate and arterial pressure. The patients were then transferred into the operating theatre and assessments were continued at 30 min intervals thereafter until complete motor and sensory blocks regression. Data were analysed using a standard computer-based statistics package.Mean time of onset of sensory blockade for levobupivacaine was 3.85±0.5 min and in Ropivacaine was 3.90 ± 0.6 min. Mean time of onset of motor blockade in levobupivacaine group was 3.65 ± 0.72 min and in Ropivacaine group was 3.82 ± 0.88 min, mean duration of motor blockade in Levobupivacaine group was 201.15±22.06 min and in Ropivacaine group was 204 ± 21.20 min. Mean time for regression for levobupivacaine was 98.27±10.18 min and for ropivacaine was 96.33 ±8.21min. There is no significant difference, Mean time for first request of analgesic for Levobupivacaine was 262.22 ±36.60 and for Ropivacaine was 261.20 ± 32.71 min. There is no statistically significant difference; there was no statistically significant difference in the incidence of adverse events in both the groups. So both the drugs are considered to be safe in spinal anesthesia.In conclusion, Ropivacaine and Levobupivacaine has similar onset of sensory and motor blockade with comparable hemodynamic parameters and time for rescue analgesic administration was comparable between two groups and incidence of post- operative complications is not significant with both drugs.
Antioxidant, Antimicrobial and Antidiabetic activities of Insulin plant rhizome extracts - A comparative study
Authors: Sivakumar G. , Sathish Kumar R. , Aruna P. , Perumal Laksmana 
Published: July 2023

retained the name as Insulin plant through traditional practice, further phytochemical and pharmacological evaluation of leaves of the plant has proven record on wider therapeutic potential such as antioxidant, antimicrobial and antidiabetic activity. Our interest of current research is to explore the rhizome by multiple extraction and to screen and find out the specific therapeutic potential of the specific extracts through relevant phytochemical and pharmacological evaluation. DPPH, Disc Diffusion and DNS methods were chosen to evaluate antioxidant and antibacterial and antidiabetic activity on various rhizome extracts (ethyl acetate, methanol, ethanol and aqueous). The anti-oxidant effect is significantly high and almost same for all rhizome extracts. ethyl acetate, ethanol, methanol has moderate antibacterial activity against gram positive ( and) and gram negative organism ( and ) by disc diffusion method as compare to the standard drug (Ceftrioxone sodium). However, aqueous extract lacs antibacterial activity. The α-amylase inhibition activity by DNS method result infers, high antidiabetic activity for ethyl acetate and ethanolic rhizome extracts whereas mild activity for methanolic and aqueous rhizome extracts. Thereby e thonolicrhizome extract might be a good choice for antioxidant, antibacterial and antidiabetic therapeutic segments among the rhizome extracts.