bluuebunny/crossref_metadata_2025_split huggingface dataset:
Health care experiences of Black cancer survivors: A qualitative study exploring drivers of low and high Consumer Assessment of Healthcare Providers and Systems global ratings of care
Authors: Ochoa‐Dominguez Carol Y. , Garrett Elleyse , Navarro Stephanie , Toledo Gabriela , Rodriguez Claudia , Iyawe‐Parsons Aisa , Farias Albert J. 
Published: July 2023

AbstractBackgroundThe purpose of this study was to understand the experiences of Black patients with cancer in health care by comparing drivers of high and low ratings.MethodsSemistructured in‐depth interviews were conducted with 18 Black patients with cancer recruited from cancer survivorship support groups and Facebook between May 2019 and March 2020. Interviews were coded across all transcripts by using a thematic analysis approach before comparing low‐ and high‐rating groups.ResultsThere were three major themes that influenced whether patients rated their care as low or high, which included the patient–provider relationship, health care staff interactions, and cancer care coordination. For example, the high‐rating group described good communication with the health care team as physicians listening to their needs, being responsive to their concerns, and providing recommendations on how to address side effects. In contrast, the low‐rating group described poor communication with their health care team as their needs being dismissed and being excluded from decision‐making processes. Additionally, there were two distinct themes that influenced patients’ low ratings: insurance and financial toxicity issues and experiences of health care discrimination.ConclusionsIn an effort to promote equitable cancer care experiences for Black patients, it is important that health systems work to prioritize patient interactions with health care providers and staff, comprehensive care management for patients with cancer, and reductions in the financial burden of caring for cancer.
Increasing the Sodium Metal Electrode Compatibility with the Na3PS4 Solid‐State Electrolyte through Heteroatom Substitution
Authors: Bekaert Lieven , Akatsuka Suzuno , Tanibata Naoto , De Proft Frank , Hubin Annick , Mamme Mesfin Haile , Nakayama Masanobu 
Published: July 2023

AbstractRechargeable batteries are essential to the global shift towards renewable energy sources and their storage. At present, improvements in their safety and sustainability are of great importance as part of global sustainable development goals. A major contender in this shift are rechargeable solid‐state sodium batteries, as a low‐cost, safe, and sustainable alternative to conventional lithium‐ion batteries. Recently, solid‐state electrolytes with a high ionic conductivity and low flammability have been developed. However, these still face challenges with the highly reactive sodium metal electrode. The study of these electrolyte‐electrode interfaces is challenging from a computational and experimental point of view, but recent advances in molecular dynamics neural‐network potentials are finally enabling access to these environments compared to more computationally expensive conventional ab‐initio techniques. In this study, heteroatom‐substituted Na3PS3X1 analogues, where X is sulfur, oxygen, selenium, tellurium, nitrogen, chlorine, and fluorine, are investigated using total‐trajectory analysis and neural‐network molecular dynamics. It was found that inductive electron‐withdrawing and electron‐donating effects, alongside differences in heteroatom atomic radius, electronegativity, and valency, influenced the electrolyte reactivity. The Na3PS3O1 oxygen analogue was found to have superior chemical stability against the sodium metal electrode, paving the way towards high‐performance, long lifetime and reliable rechargeable solid‐state sodium batteries.
Enhanced maternal behaviors in a mouse model of congenital blindness
Authors: Bouguiyoud Nouhaila , Xie Wen Bin , Bronchti Gilles , Frasnelli Johannes , Al Aïn Syrina 
Published: July 2023

AbstractIn mammals, mothering is one of the most important prosocial female behavior to promote survival, proper sensorimotor, and emotional development of the offspring. Different intrinsic and extrinsic factors can initiate and maintain these behaviors, such as hormonal, cerebral, and sensory changes. Infant cues also stimulate multisensory systems and orchestrate complex maternal responsiveness. To understand the maternal behavior driven by complex sensory interactions, it is necessary to comprehend the individual sensory systems by taking out other senses. An excellent model for investigating sensory regulation of maternal behavior is a murine model of congenital blindness, the ZRDBA mice, where both an anophthalmic and sighted mice are generated from the same litter. Therefore, this study aims to assess whether visual inputs are essential to driving maternal behaviors in mice. Maternal behaviors were assessed using three behavioral tests, including the pup retrieval test, the home cage maternal behavior test, and the maternal aggression test. Our results show that blind mothers (1) took less time to retrieve their offspring inside the nest, (2) spent more time nursing and licking their offspring in the second‐ and third‐week postpartum, and (3) exhibited faster aggressive behaviors when exposed to an intruder male, compared to the sighted counterparts. This study provides evidence that congenitally blind mothers show more motivation to retrieve the pups, care, and protection towards their pups than sighted ones, likely due to a phenomenon of sensory compensation.
A descriptive review of the use of organic acids and peracetic acid as a decontaminating strategy for meat
Authors: Rossi Gabriel Augusto Marques , Link Daniella Tosta , Bertolini Amanda Bezerra , Tobias Fernando Luiz , Mioni Mateus de Souza Ribeiro 
Published: July 2023

AbstractMeat can be a pathogen vehicle, and its spoilage contributes to food insecurity. Besides the importance of adopting good hygienic practices to avoid meat contamination, several decontaminating strategies have been studied. This review discusses the mechanisms of action of organic acids and peracetic acid, the factors that affect their efficacy, and compiles information about their microbiological and sensorial effects on meat. Factors that affect their efficacy include the species of microorganisms, the acid‐susceptibility within the same species, the initial contamination degree, the organic acid used and concentration, pH and volume of solutions, methods of application, contact time, steps of a flowchart where the treatment occurred and quantity of applications, site of carcass/meat treated and tissues composition, and combinations with other decontaminating treatments. Inspite of the amount of available data, the log reductions with their standard deviations and the temperature of solutions applied are rarely presented; and several studies lack information on the pH of the solutions. This strategy will be helpful for industries, contributing to enhanced food security and safety. However, studies for in loco validation must be performed before implementing these treatments.
Functional and structural networks decoupling in generalized tonic–clonic seizures and its reorganization by drugs
Authors: Pei Haonan , Ma Shuai , Yan Wei , Liu Zetao , Wang Yuehan , Yang Zhihuan , Li Qifu , Yao Dezhong , Jiang Sisi , Luo Cheng , Yu Liang 
Published: July 2023

AbstractObjectiveTo investigate potential functional and structural large‐scale network disturbances in untreated patients with generalized tonic–clonic seizures (GTCS) and the effects of antiseizure drugs.MethodsIn this study, 41 patients with GTCS, comprising 21 untreated patients and 20 patients who received antiseizure medications (ASMs), and 29 healthy controls were recruited to construct large‐scale brain networks based on resting‐state functional magnetic resonance imaging and diffusion tensor imaging. Structural and functional connectivity and network‐level weighted correlation probability (NWCP) were further investigated to identify network features that corresponded to response to ASMs.ResultsUntreated patients showed more extensive enhancement of functional and structural connections than controls. Specifically, we observed abnormally enhanced connections between the default mode network (DMN) and the frontal–parietal network. In addition, treated patients showed similar functional connection strength to that of the control group. However, all patients exhibited similar structural network alterations. Moreover, the NWCP value was lower for connections within the DMN and between the DMN and other networks in the untreated patients; receiving ASMs could reverse this pattern.SignificanceOur study identified alterations in structural and functional connectivity in patients with GTCS. The influence of ASMs may be more noticeable within the functional network; moreover, abnormalities in both the functional and structural coupling state may be improved by ASM treatment. Therefore, the coupling state of structural and functional connectivity may be used as an indicator of the efficacy of ASMs.
Clinical characteristics and follow‐up of children with norovirus‐associated benign convulsions with mild gastroenteritis
Authors: Shi Kaili , Jiang Daoju , Yang Jiehui , Li Ying , Chen Wenxiong , Li Peiqing 
Published: July 2023

AbstractObjectiveExplore the clinical characteristics and prognosis of children with norovirus (NoV)‐associated benign convulsions with mild gastroenteritis (CwG).MethodsWe retrospectively analyzed the Clinical and laboratory data of children with NoV‐associated CwG admitted to the emergency department of Guangzhou Children's Hospital between January 2019 and January 2020. And patients were followed up for 23–36 months.ResultsThere are 49 cases met the CwG criteria. Vomiting was the first symptom in 31 (63.3%) patients, and vomiting could be the main or the only gastrointestinal symptom. The mean frequency of seizures was 3.8 ± 2.4 episodes. Most patients (95.9%) experienced seizures that lasted for less than 5 min. Of the 43 (87.8%) cases followed up from 23 to 36 months, only one experienced recurrent convulsions (after rotavirus infection).SignificanceNoV‐associated CwG patients were prone to experiencing more convulsions. However, because most NoV‐associated CwG patients had good prognosis, long‐term use of anticonvulsants are unnecessary.
The somatic p.T81dup variant in AKT3 gene underlies a mild cerebral phenotype and expands the spectrum including capillary malformation and lateralized overgrowth
Authors: Luca Maria , Piglionica Marilidia , Bagnulo Rosanna , Cardaropoli Simona , Carli Diana , Turchiano Antonella , Coppo Paola , Pantaleo Antonino , Iacoviello Matteo , Ferrero Giovanni Battista , Mussa Alessandro , Resta Nicoletta 
Published: July 2023

AbstractHeterozygous germline or somatic variants in AKT3 gene can cause isolated malformations of cortical development (MCDs) such as focal cortical dysplasia, megalencephaly (MEG), Hemimegalencephaly (HME), dysplastic megalencephaly, and syndromic forms like megalencephaly‐polymicrogyria‐polydactyly‐hydrocephalus syndrome, and megalencephaly‐capillary malformation syndrome. This report describes a new case of HME and capillary malformation caused by a somatic AKT3 variant that differs from the common p.E17K variant described in literature. The patient's skin biopsy from the angiomatous region revealed an heterozygous likely pathogenic variant AKT3:c.241_243dup, p.(T81dup) that may affect the binding domain and downstream pathways. Compared to previously reported cases with a common E17K mosaic variant, the phenotype is milder and patients showed segmental overgrowth, an uncommon characteristic in AKT3 variant cases. These findings suggest that the severity of the disease may be influenced not only by the level of mosaicism but also by the type of variant. This report expands the phenotypic spectrum associated with AKT3 variants and highlights the importance of genomic analysis in patients with capillary malformation and MCDs.
Spatiotemporal profile of atrophy in the first year following moderate‐severe traumatic brain injury
Authors: Brennan Daniel J. , Duda Jeffrey , Ware Jeffrey B. , Whyte John , Choi Joon Yul , Gugger James , Focht Kristen , Walter Alexa E. , Bushnik Tamara , Gee James C. , Diaz‐Arrastia Ramon , Kim Junghoon J. 
Published: July 2023

AbstractTraumatic brain injury (TBI) triggers progressive neurodegeneration resulting in brain atrophy that continues months‐to‐years following injury. However, a comprehensive characterization of the spatial and temporal evolution of TBI‐related brain atrophy remains incomplete. Utilizing a sensitive and unbiased morphometry analysis pipeline optimized for detecting longitudinal changes, we analyzed a sample consisting of 37 individuals with moderate‐severe TBI who had primarily high‐velocity and high‐impact injury mechanisms. They were scanned up to three times during the first year after injury (3 months, 6 months, and 12 months post‐injury) and compared with 33 demographically matched controls who were scanned once. Individuals with TBI already showed cortical thinning in frontal and temporal regions and reduced volume in the bilateral thalami at 3 months post‐injury. Longitudinally, only a subset of cortical regions in the parietal and occipital lobes showed continued atrophy from 3 to 12 months post‐injury. Additionally, cortical white matter volume and nearly all deep gray matter structures exhibited progressive atrophy over this period. Finally, we found that disproportionate atrophy of cortex along sulci relative to gyri, an emerging morphometric marker of chronic TBI, was present as early as 3 month post‐injury. In parallel, neurocognitive functioning largely recovered during this period despite this pervasive atrophy. Our findings demonstrate msTBI results in characteristic progressive neurodegeneration patterns that are divergent across regions and scale with the severity of injury. Future clinical research using atrophy during the first year of TBI as a biomarker of neurodegeneration should consider the spatiotemporal profile of atrophy described in this study.
Rift valley fever (RVF) viral zoonotic disease steadily circulates in the Mauritanian animals and humans: A narrative review
Authors: Mohapatra Ranjan K. , Kutikuppala Lakshmi V. S. , Kandi Venkataramana , Mishra Snehasish , Rabaan Ali A. , Costa Sharo , Al‐qaim Zahraa Haleem , Padhi Bijaya K. , Sah Ranjit 
Published: July 2023

AbstractBackground and AimRift valley fever (RVF) virus (RVFV) is reportedly steadily circulating in Mauritania being repeated in 1987, 2010, 2012, 2015, and 2020. Mauritania seems a preferred niche for RVF virus due to its persistent outbreak there. Lately, nine Mauritanian wilayas confirmed 47 (23 fatalities with 49% CFR) human cases between August 30 and October 17, 2022. Most of the cases were largely among livestock breeders associated with animal husbandry activities. The review aimed at understanding the origin, cause, and measures to counter the virus.MethodsThe facts and figures from the various published articles sourced from databases including Pubmed, Web of Science, and the Scopus as also some primary data from health agencies like WHO, CDC, and so forth were evaluated and the efficacy of countermeasures reviewed.ResultsAmong the reported confirmed cases, it was found that 3−70 year age‐group males outnumbered the females. Deaths after fever occurred primarily due to acute hemorrhagic thrombocytopenia. Human infections often occurred through zoonotic transmission mainly through mosquitoes in the population contiguous to cattle outbreak, a conducive site for local RVFV transmission. Many transmission cases were through direct or indirect contact with blood or organs of the infected animal.ConclusionRVFV infection was predominant in the Mauritanian regions bordering Mali, Senegal, and Algeria. High human and domesticated animal density as also the existing zoonotic vectors further contributed to RVF virus circulation. Mauritanian RVF infection data confirmed that RVFV was zoonotic that included small ruminants, cattle, and camel. This observation hints at the role of transborder animal mobility in RVFV transmission. In light of this, preventive approaches with effective surveillance and monitoring system following the One Health model is extremely beneficial for a free and fair healthy world for all.
Three‐dimensional numerical simulation of free convection and entropy generation in a cubic cavity containing a heat source
Authors: Benhamou Jaouad , Lahmer El Bachir , Admi Youssef , Jami Mohammed , Mezrhab Ahmed 
Published: July 2023

AbstractThe present article provides a three‐dimensional numerical investigation of thermal convection and entropy generation. The lattice Boltzmann method, coupled with the finite difference approach, is applied to perform numerical simulations. The validation of these numerical approaches for thermal convection simulation and entropy calculation is performed by comparing our numerical results with those in the published literature for the case of benchmark problems. The physical geometry studied in this paper concerns a hot obstacle having the shape of a plus sign (+) placed in the center of a cubic enclosure. This cube is filled with air of a Prandtl number of 0.71 and characterized by two cold vertical walls. The heat exchange between the fluid and the hot body is studied as a function of the Rayleigh number (). The performed simulations show that the heat transfer rate can be increased by about 429% by switching from to . The entropy generation due to fluid friction, heat transfer, and total entropy are also calculated and discussed. For an irreversibility coefficient , the analysis of the results showed that for low values of the Rayleigh number (), the entropy production due to temperature gradients predominates over that produced by viscous effects. In the cases of and , entropy generation is due to both fluid friction and heat transfer. However, when the Rayleigh number becomes large (), entropy generation due to viscosity predominates over entropy production related to heat exchange. These results have important implications for the optimization and design of heat transfer systems in various industrial applications.
Magnetohydrodynamic micropolar slip flow due to an exponentially stretching sheet with chemical reaction and nonuniform heat generation
Authors: Choudhary Sushila , Vaishnav Bal Krishn , Yadav Bhagawan Singh 
Published: July 2023

AbstractThe main focus of the current study is to examine the impact of melting heat transfer and chemical reaction on magnetohydrodynamic micropolar fluid flow over a sheet that is exponentially stretching and immersed in a porous medium. A nonuniform heat source is placed within this flow system. Other impacts like slip phenomena and thermal radiation are also taken into consideration. The governing partial differential equations are converted to a system of ordinary differential equations (ODEs) via similarity transformation and we also get the corresponding necessary boundary conditions. These nonlinear ODEs are resolved with the help of shooting technique and an Runge‐Kutta fourth order (RK‐4) iterative strategy. Also, we solve this problem using the Bvp4c approach for validating the results of the RK‐4 method. Both outcomes are consistent with previously published data. With the help of tables and graphs, we examine the influence of multiple physical parameters on velocity, thermal, microrotation, concentration, Nusselt number, Sherwood number, coefficient of skin friction, and wall couple stress. We see that the temperature distribution and velocity profiles decrease when the melting parameter increases. The temperature profile boosts when the heat source parameter is increased.
Atypical eclampsia in a normotensive patient with altered mental status and severely elevated transaminases: Case report and review
Authors: Ghadiali Tejal , Nguyen Michelle T. , Lee Richard H. , Sasso Elizabeth B. 
Published: July 2023

AbstractClassically, pre‐eclampsia and eclampsia are considered hypertensive disorders of pregnancy, and current diagnostic criteria include hypertension with proteinuria or other laboratory abnormalities or symptoms suggestive of end‐organ damage. However, atypical presentations can occur in the absence of elevated blood pressures. We present the case of a pregnant patient who developed status epilepticus at 24 weeks and 4 days of gestation, followed by altered mental status and severely elevated transaminases. She had no elevated blood pressures during her prenatal care or hospital course. Following delivery, she experienced normalization of transaminase levels and a return to her baseline mental status. Pre‐eclampsia and eclampsia can occur in the absence of elevated blood pressures, which highlights the limitations of using standard diagnostic criteria in normotensive patients with end‐organ damage. In such cases, it is important to include pre‐eclampsia and eclampsia in the differential diagnosis, as the diagnosis usually warrants preterm delivery to minimize maternal morbidity and mortality.
心停止で搬入され，damage control strategy下に多期的手術を行い，神経学的後遺症なく救命できたmesenteric inflammatory veno–occlusive disease(Successful recovery from out–of–hospital cardiac arrest caused by mesenteric inflammatory veno–occlusive disease without neurological sequelae under damage control strategy: a case report)
Authors: 大輝 南出 , 研二 神鳥 , 道太郎 宮国 , 亘 石井 , 亮二 飯塚 
Published: July 2023

要旨　Mesenteric inflammatory veno–occlusive disease（MIVOD）は消化管および腸間膜に限局した原因不明の静脈炎により消化管虚血を来す稀な疾患で，一期的手術により予後は良好とされる。MIVODによる心停止で搬入され，蘇生後にdamage control strategyに基づく多期的手術と集中治療で救命し得たので報告する。81歳女性が12時間前からの腹痛，嘔吐で救急要請し，救急車内で心停止となった後，当院搬入となった。自己心拍は再開したが呼吸・循環状態は不安定であった。CTで腸管虚血を認め，緊急開腹術で壊死小腸を切除した。全身状態安定化と腸管壊死範囲拡大の可能性を考慮しdamage control strategyに基づき，damage control surgery（DC）およびopen abdominal management（OAM）を行った。壊死範囲の拡大に対してDC2とDC3で回盲部とS状結腸を切除しOAMを継続した。DC4で腸管虚血所見を認めず，人工肛門を造設し，根治的に閉腹した。経過良好で第64病日に神経学的後遺症なく退院した。全切除病理検体でMIVOD所見を認めた。MIVODが致死的となることを認識し，全身状態が不安定な症例はdamage control strategy のもと多期的手術が有効な可能性がある。
Delay characterization of multilayer graphene nanoribbon interconnects in presence of scattering and thermal effects
Authors: Upadhyay Akanksha , Rai Mayank Kumar , Khanna Rajesh 
Published: July 2023

AbstractScattering source‐based mean free path (MFP) and circuit modeling are proposed for three different configurations of undoped multilayer graphene nanoribbon (U‐MLGNR) (viz. horizontal top‐contact (HTC), horizontal side‐contact (HSC), and vertical top‐contact (VTC)). A similar analysis is carried out for doped HTC‐MLGNR (D‐HTC‐MLGNR) considering dopants viz. Li, FeCl3, and AsF5, for a temperature range of 300–500 K. The optimistic intrinsic‐phonon limited (Λeff,1(T)) and realistic scattering limited (Λeff,2(T)) effective MFP models are considered to derive the equivalent resistance of MLGNR. The performance of MLGNR variants, considering Λeff,1(T) and Λeff,2(T), is compared to copper (Cu) (with smooth and rough surface) in terms of coupled line crosstalk‐induced delay (XT‐D). The results show that the MLGNR variants outperform Cu interconnects in terms of XT‐D, for Λeff,1(T). However, structural edge roughness being the dominant scattering source in Λeff,2(T), severely degrades the performance of MLGNR variants in comparison to Cu counterparts. Moreover, for Λeff,1(T) and Λeff,2(T), Li‐D HTC‐MLGNR outperforms other MLGNR variants. Also, among the MLGNR variants, U‐VTC‐MLGNR exhibits a minimum average relative penalty of 21.58 × 102% in terms of XT‐D, when Λeff,2(T) is considered as against Λeff,1(T). Li‐D HTC‐MLGNR with optimized width exhibits 10.59× lower XT‐D and 8.85× higher XT‐D for Λeff,1(T) and Λeff,2(T), respectively, compared to smooth Cu. The optimized Li‐D HTC‐MLGNR demonstrates a reduction of 85.48% and 74.67% in XT‐D values for Λeff,1 (T) and Λeff,2 (T), respectively, when compared to mixed carbon nanotube (MCNT) bundle interconnects.