bluuebunny/crossref_metadata_2025_split huggingface dataset:
Se rapprocher du « réel » ou diversifier les compétences ? Un atelier coopératif de conception architecturale à l’ENSA de Clermont-Ferrand
Authors: Laporte Rémi 
Published: January 2025

Dans les écoles nationales supérieures d’architecture françaises (ENSA), la dernière décennie a vu s’exprimer une demande étudiante significative en faveur d’un rapprochement des programmes pédagogiques du « réel » des pratiques et des enjeux sociétaux actuels. Ce phénomène, qui fait écho à des préoccupations déjà exprimées dès la fin des années 1960 et aux expérimentations qui en ont découlé, s’accompagne aujourd’hui dans la plupart des ENSA de l’essor non concerté d’enseignements de conception architecturale revendiquant cet objectif, et recourant à des procédés de pédagogie coopérative et pluridisciplinaire. Constatant que cette évolution recouvre des orientations communes mais aussi une diversité de situations et reste peu traitée par la littérature, cet article propose de contribuer à la documenter via une analyse réflexive de l’un de ces enseignements. L’intention est de clarifier les fondements théoriques auxquels il renvoie et les dispositifs didactiques qu’il met en œuvre pour développer un apprentissage coopératif de la conception architecturale visant l’acquisition d’une gamme élargie de compétences. Il s’agit aussi de caractériser la nature de cette coopération et des relations d’acteurs qu’ils permettent de créer en les rapprochant du concept de transaction sociale, et d’en identifier les limites et les biais induits, tant dans le processus d’enseignement que dans ses résultats.
Thrombomodulin and Lactate Dehydrogenase as Potential Predictors of Leg Ulcers in Sickle Cell Disease
Authors: Okoye Helen C. , Ocheni Sunday , Eweputanna Lisa I. , Nwagha Theresa U. , Ejezie Chioma S. , Nonyelu Charles E. , Nnachi Oji A. , Obodo Onochie I. , Awodu Omolade A. 
Published: January 2025

Abstract

Background:
Endothelial dysfunction, hypercoagulability, hemolysis, and vasculopathy are involved in the pathogenesis of sickle cell leg ulcers (SCLUs). Understanding these processes is crucial for developing effective strategies to manage and prevent SCLU.

Objectives:
To evaluate the plasma levels of thrombomodulin (TM) in patients with SCLU, determine if TM levels have any association with SCLU and its severity, and determine if TM has any association with markers of hemolysis.

Materials and Methods:
This was a cross-sectional analytical study carried out among patients with SCLU and their age-matched sickle cell disease (SCD) patients without leg ulcers. Venous blood samples were collected for the determination of TM and lactate dehydrogenase (LDH) levels. Statistical significance across means was determined using independent t tests and the one-way analysis of variance (ANOVA). Pearson’s correlation and linear regression analysis were used to determine the relationship between variables.

Results:
Of the 82 patients with SCD, 41 had SCLU (test group), and 41 had no SCLU (control group). Their mean age was 33.3 ± 9.0 and 33.0 ± 8.5 (P = 0.30), respectively. There was no significant statistical difference between plasma levels of TM and number (P = 0.191) and severity (P = 0.148) of SCLU. Seventy-three (89%) SCD patients had LDH concentration above the reference limit of normal, and 9 (11%) were within normal limits (P = 0.002). None of the test (SCLU) group patients had normal LDH values.

Conclusion:
SCLU is associated with higher levels of LDH, whereas plasma TM levels showed no association with the occurrence and severity of SCLU.
Products of commutators in matrix rings
Authors: Brešar Matej , Gardella Eusebio , Thiel Hannes 
Published: January 2025

Abstract
Let R be a ring and let

$n\ge 2$

. We discuss the question of whether every element in the matrix ring

$M_n(R)$

is a product of (additive) commutators

$[x,y]=xy-yx$

, for

$x,y\in M_n(R)$

. An example showing that this does not always hold, even when R is commutative, is provided. If, however, R has Bass stable rank one, then under various additional conditions every element in

$M_n(R)$

is a product of three commutators. Further, if R is a division ring with infinite center, then every element in

$M_n(R)$

is a product of two commutators. If R is a field and

$a\in M_n(R)$

, then every element in

$M_n(R)$

is a sum of elements of the form

$[a,x][a,y]$

with

$x,y\in M_n(R)$

if and only if the degree of the minimal polynomial of a is greater than

$2$

.
Compactifications of pseudofinite and pseudoamenable groups
Authors: Conant Gabriel , Hrushovski Ehud , Pillay Anand 
Published: January 2025

We first give simplified and corrected accounts of some results in work by Pillay (2017) on compactifications of pseudofinite groups. For instance, we use a classical theorem of Turing (1938) to give a simplified proof that any definable compactification of a pseudofinite group has an abelian connected component. We then discuss the relationship between Turing’s work, the Jordan–Schur theorem, and a (relatively) more recent result of Kazhdan (1982) on approximate homomorphisms, and we use this to widen our scope from finite groups to amenable groups. In particular, we develop a suitable continuous logic framework for dealing with definable homomorphisms from pseudoamenable groups to compact Lie groups. Together with the stabilizer theorems of Hrushovski (2012) and Montenegro et al. (2020), we obtain a uniform (but non-quantitative) analogue of Bogolyubov’s lemma for sets of positive measure in discrete amenable groups. We conclude with brief remarks on the case of amenable topological groups.
РАБОЧИЕ ОРГАНЫ ДЛЯ РАЗРУШЕНИЯ ЛЬДА НА ДОРОГАХ И ТРОТУАРАХ С РЕГУЛИРОВКОЙ РАЗРУШАЮЩЕГО ВОЗДЕЙСТВИЯ
Authors: С. Р. Байгереев  , Г. А. Гурьянов  , А. Д. Сулейменов  , О. Ю. Васильева  , Х. А. Абшенов  
Published: January 2025

Обледенение дорог и тротуаров является одной из актуальных проблем, влияющих на безопасность дорожного движения. В зимний период для борьбы со скользкостью на дорогах и тротуарах часто применяют механический способ удаления льда с их поверхности. Эффективным механическим способом удаления льда с дорог и тротуаров является его разрушение ударным воздействием твердой сферической поверхностью, для чего были разработаны новые рабочие органы. В результате теоретических исследований получены теоретические расчетные зависимости механико-математической модели для определения параметров рабочего органа ударного действия со сферической рабочей поверхностью для разрушения льда, учитывающие характеристики льда, позволяющие проводить инженерные расчеты и определять как на стадии разработки и проектирования, так и в процессе работы, параметры рабочего органа ударного действия со сферическими бойками и подбирать такую величину разрушающего воздействия рабочего органа на лед, при которой возможно разрушить лед заданной прочности и толщины. Разработаны несколько конструктивных решений рабочих органов для разрушения льда на дорогах с регулированием величины разрушающего воздействия на лед изменением радиуса расположения бойка относительно оси вращения рабочего органа, которые за счет возможности адаптации к условиям работы имеют высокую эффективность при разрушении льда и качество очистки дорожных покрытий. Результаты исследований позволяют разрабатывать усовершенствованные конструкции рабочих органов
с повышенной технологической и экономической эффективностью.
Ключевые слова: рабочий орган, ледоскалывающая машина, разрушение льда, безопасность движения, математическая модель.
Do the Macroeconomic variables influence Exchange Traded Funds (ETFs)?
Authors: Chaitanya Suresh Kittur  
Published: January 2025

Exchange Traded Funds (ETFs) are essentially Index Funds that are listed and traded on exchanges like stocks. Until the development of ETFs, this was not possible before. Globally, ETFs have opened a whole new panorama of investment opportunities to Retail as well as Institutional Money Managers. They enable investors to gain broad exposure to entire stock markets in different Countries and specific sectors with relative ease, on a real-time basis and at a lower cost than many other forms of investing. An ETF is a basket of stocks that reflects the composition of an Index, like S&P CNX Nifty or BSE Sensex. The ETFs trading value is based on the net asset value of the underlying stocks that it represents. Think of it as a Mutual Fund that you can buy and sell in real-time at a price that change throughout the day. Compared to mutual funds, ETFs are relatively new. The first U.S. ETFs were created by State Street Global Advisors with the launch of the S&P 500 depositary receipts, also known as SPDRs ("spiders"). Although the first ETFs tended to track broad market indexes, more recent ETFs have been developed to track sectors, fixed income, global investments, commodities and currencies. There exists correlation between ETF and macroeconomic variables and also change in independent variables causes change in dependent variable. However, the degree of variability differs. These variables form significant part and the level of prediction is also good. Therefore, the model is good fit for the data. An investor needs to guise into these while taking investment decision.
Kajian Kepatuhan Sarana Produksi Minyak Goreng Sawit di Wilayah Kerja BBPOM di Bandung dan BBPOM di Surabaya dalam Melakukan Fortifikasi Vitamin A
Authors: Utami Setyo , Andriany Dinny 
Published: January 2025

Kekurangan vitamin A (KVA) merupakan masalah kesehatan masyarakat di berbagai negara, termasuk Indonesia. Salah satu strategi pemerintah yang untuk mengatasi KVA adalah dengan melakukan fortifikasi vitamin A pada bahan pangan. Minyak goreng sawit (MGS) merupakan bahan pangan yang difortifikasi dengan vitamin A. Kebijakan fortifikasi vitamin A telah diatur dalam SNI 7709-2019 melalui Peraturan Menteri Perindustrian Nomor 46 Tahun 2019, yang mewajibkan produsen menambahkan fortifikan vitamin A sehingga didapatkan kadar vitamin A minimal 45 IU/g terhadap MGS yang disampling. Penelitian ini bertujuan untuk melihat kepatuhan sarana produksi MGS di wilayah kerja Balai Besar Pengawas Obat dan Makanan (THE INDONESIAN FDA REGIONAL OFFICE) di Bandung dan THE INDONESIAN FDA REGIONAL OFFICE di Surabaya dalam melakukan fortifikasi Vitamin A. Penelitian ini menggunakan metode penelitian deskriptif dengan pendekatan kualitatif. Data penelitian adalah data hasil sampling dan pengujian minyak goreng sawit yang dilakukan oleh THE INDONESIAN FDA REGIONAL OFFICE di Bandung dan THE INDONESIAN FDA REGIONAL OFFICE di Surabaya sesuai dengan Pedoman Sampling dan Pengujian Obat dan Makanan dan data hasil pemeriksaan pada wilayah kerja THE INDONESIAN FDA REGIONAL OFFICE di Bandung dan THE INDONESIAN FDA REGIONAL OFFICE di Surabaya pada 2021 sampai dengan 2023. Hasil penelitian menunjukkan masih terdapat sarana produksi yang belum melakukan fortifikasi vitamin A karena kurangnya komitmen terhadap kewajiban fortifikasi dan penyediaan Vitamin A. Secara keseluruhan, selama periode 1021-2023 terdapat 31,58% sarana produksi yang tidak memenuhi ketentuan. Terdapat hubungan antara jenis sarana dan ketidakpatuhan dalam menambahkan fortifikan vitamin A pada MGS. Relaksasi regulasi karena harga MGS yang meningkat menyebabkan program fortifikasi MGS dengan vitamin A terjadi sejak tahun Januari 2022 (misalnya). Oleh karena itu konsistensi program fortifikasi vitamin A pada MGS harus dilaksanakan kembali.
Impacto del entrenamiento en plataformas vibratorias en la rehabilitación post-quirúrgica del ligamento cruzado anterior. Una revisión sistemática
Authors: Santamaría Gómez Gema , López-Llorente Álvaro , Garrosa Evelina , Fernández-Lázaro Diego 
Published: January 2025

El objetivo de este estudio fue revisar la evidencia disponible sobre la efectividad del entrenamiento en plataformas de vibración de cuerpo entero (WBV) en comparación con la rehabilitación convencional en la recuperación postquirúrgica del ligamento cruzado anterior (LCA). Siguiendo las directrices “Prefered Reporting Items for Systematic Review and Meta-anlisis” (PRISMA) se realizó una búsqueda sistemática en las bases de datos PubMed, Cochrane, Scopus, Web of Science y “Physiotherapy Evidence Database” (PEDro) hasta julio de 2024. Se incluyeron todos los ensayos clínicos aleatorizados cuyo grupo intervención realizara WBV postcirugía de LCA. Se comprobó la calidad metodológica mediante la escala CASPe, PEDro y Cochrane. De los 470 registros identificados 7 cumplieron los criterios de selección. En general, a pesar de haber una tendencia a la mejora (p>0,05) de la fuerza respecto al grupo control, no se observaron aumentos significativos. Por otro lado, se encontraron incrementos significativos (p<0,05) del equilibrio y la Escala Lysholm de funcionalidad de la rodilla respecto al grupo control. En conclusión, la terapia de WBV puede constituir una estrategia efectiva en la rehabilitación de pacientes con reconstrucción de LCA, mostrando resultados positivos en la fuerza de la musculatura de la rodilla, el equilibrio, el control postural y la Escala de Lysholm. Además, la WBV ha demostrado ser superior a la rehabilitación convencional en el aumento de la fuerza, equilibrio y la Escala de Lysholm. Sin embargo, no hay consenso sobre la efectividad de ambas terapias en el control postural y la oscilación del centro de presiones.
ĐÁNH GIÁ MỐI LIÊN QUAN GIỮA GIÁ TRỊ TIÊN LƯỢNG CỦA PET/CT VÀ ĐÁP ỨNG SAU HOÁ XẠ TRỊ ĐỒNG THỜI Ở NHÂN UNG THƯ THỰC QUẢN GIAI ĐOẠN III KHÔNG PHẪU THUẬT ĐƯỢC
Authors: Mai Thị Quỳnh , Phạm Lâm Sơn , Trần Thế Hoàng , Châu Quỳnh Anh , Nguyễn Quang Toàn 
Published: January 2025

Mục đích : Đánh giá mối liên quan giữa giá trị tiên lượng của PET/CT và đáp ứng sau hoá xạ trị đồng thời ở bệnh nhân ung thư thực quản giai đoạn III không phẫu thuật được.
Đối tượng và phương pháp: Nghiên cứu (NC) mô tả hồi cứu và tiến cứu 48 Bệnh nhân ung thư thực quản biểu mô vảy giai đoạn III (T1,2N2M0 hoặc T3,N1,2,M0) bệnh nhân được chụp PET/CT tính toán các giá trị (SUVmax,MTV,TLG) của tổn thương u thực quản, sau đó được điều trị hoá xạ trị đồng thời tại bệnh viện K thời gian từ tháng 1/2023 đến tháng 6/2024. Theo dõi dọc qúa trình điều trị và sau điều trị tìm mối liên quan giữa giá trị PET/CT và tiên lượng dựa vào thời gian sống thêm không bệnh (PFS) và toàn bộ (OS).
Kết quả: Nhóm NC 100% nam giới, tuổi trung bình 61,25± 6,67 tuổi. Tiền sử hút thuốc và lạm dụng rượu bia 81,25 %. Vị trí tổn thương hay gặp 1/3 giữa (45,8%), hai đoạn thực quản (22,9%), ít gặp ở đoạn 1/3 trên (10,4%). Giai đoạn trước điều trị T1,2N2 (43,8%) và T3,N1,2 (56,3%). Phân tích đường cong ROC cho các thông số PET/CT nhóm NC liên quan đến giai đoạn cT3 tương ứng SUVmax > 18,5 g/mL (độ nhạy 51,9%, độ đặc hiệu 76,2%, p < 0.01), TLG > 181,5 g (độ nhạy 70 %, độ đặc hiệu 95,6%, p < 0.001), MTV > 25,5 cm3 (độ nhạy 66,7%, độ đặc hiệu 99 %, p < 0.001). Bệnh nhân điều trị hoá xạ trị đồng thời với xạ trị liều £ 50.4 (83,3%), hoá chất: FOLFOX (56.3%), XELOX (35,4%) và CF (8%). Thời gian theo dõi trung bình nhóm NC là 9,6 tháng (khoảng 3,02-18,2). Sau điều trị, 36 bệnh nhân (75%) bệnh còn tiến triển. Thời gian sống thêm không bệnh (PFS) sau 12 tháng có sự khác biệt của nhóm cT1,2 và cT3 tương ứng là 33,4% và 22,2% (p<0,05). SUVmax < 18,5 g/mL, MTV < 25.5  cm3 và TLG <181,5 g có tiên lượng tiên lượng tốt với PFS (tương ứng p<0,05, p<0,001 và p<0,01). Tuy nhiên, không có sự khác biệt các chỉ số SUVmax,MTV,TLG với thời gian sống thêm toàn bộ của nhóm NC.
Kết luận: Giai đoạn T và các thông số u thực quản trên PET/CT có ý nghĩa dự báo tiên lượng đánh giá đáp ứng sau hoá xạ trị đồng thời ở bệnh nhân ung thư thực quản biểu mô vảy giai đoạn III không phẫu thuật được.
NGHIÊN CỨU ĐÔNG KHÔ BEVACIZUMAB VÀ ĐÁNH DẤU VỚI Tc-99m ĐỂ CHỤP HÌNH MIỄN DỊCH PHÓNG XẠ UNG THƯ
Authors: Thi Thu Nguyen , Nguyen Thi Khanh Giang , Nguyễn Thị Ngọc , Nguyen Thanh Binh , Đặng Hồ Hồng Quang , Nguyễn Thanh Nhan , Phạm Thành Minh 
Published: January 2025

Tóm tắt: Mục tiêu: Bevacizumab, kháng thể đơn dòng nhân hoá kháng VEGF, được nghiên cứu đông khô và đánh dấu với 99mTc để tạo thành 99mTc-bevacizumab dùng trong chụp hình khối ung thư. Mục đích của nghiên cứu là phát triển công thức và quy trình đông khô thuốc bevacizumab. Phương pháp: Bevacizumab được khảo sát đông khô theo hàm lượng các chất, pH, nhiệt độ và thời gian. Hợp chất đông khô được kiểm tra tính ổn định, đánh dấu với đồng vị phóng xạ 99mTc, kiểm tra độ tinh khiết hoá phóng xạ và độ bền. Kết quả: Kết quả nghiên cứu cho thấy, bevacizumab được đông khô tạo thành dạng khô xốp, màu trắng, ở các điều kiện tối ưu như đệm phosphat 0,5 M, pH 7,4 ở nhiệt độ -40 ℃ và thời gian 24 giờ. Bevacizumab đông khô ổn định sau 6 tháng theo dõi. Độ tinh khiết hóa phóng xạ của 99mTc-bevacizumab đạt hơn 98 %, đạt vô khuẩn và nội độc tố vi khuẩn. Kết luận: Bevacizumab đã được điều chế dạng đông khô, có thể dùng để đánh dấu với 99mTc, đạt các chỉ tiêu về thuốc phóng xạ và có thể dùng trong các nghiên cứu tiền lâm sàng.
Monitoring and diagnosis of cardiac anomalies in hospitalized patients using IoT and LSTM neural networks
Authors: João Victor Tavares Santos  , Márcio Guilherme Silvestrini Júnior  , Thabatta Moreira Alves de Araujo  , Eduardo Habib Bechelane Maia  , Lucas Silva de Oliveira  
Published: January 2025

Continuous monitoring of patients in hospital settings is essential for preventing cardiac disease, representing a crucial measure to ensure the safety of hospitalized patients. However, current monitoring methods have significant limitations, such as patients only being monitored for short periods, which complicates the identification of changes in health status. This article presents a proof of concept for successfully implementing a continuous vital signs monitoring system using the Internet of Things (IoT), coupled with a Long Short-Term Memory (LSTM) neural network for detecting cardiac anomaly events.The development of the neural network hinged on a meticulously labeled database. This database, composed of 12-lead electrocardiogram (ECG) signals from 45,152 patients, was a labor of expertise. Collected at a sampling rate of 500 Hz, these data were labeled by experts, ensuring their high quality and reliability. This resource is fundamental for training machine learning models with high diagnostic precision, enabling accurate identification of cardiac rhythm patterns that indicate potential adverse conditions or those that deviate from a normal or stable electrocardiogram pattern. To make practical use of this extensive data, a robust system architecture was necessary to handle and analyze the data effectively.Microcontrollers played a crucial role in our system, facilitating the transmission of data to a web server. This was achieved using the Message Queuing Telemetry Transport (MQTT) protocol, a highly efficient and fast method for message transmission. The MQTT server, acting as a central hub, received the information and distributed it to two destinations. First, it sent the data to the real-time monitoring site, ensuring immediate access to patient vital signs. Second, it forwarded the data to the system hosting the neural network model. In this environment, the model processed the information and promptly identified any irregularities detected in the data.The results demonstrate that the model achieved high precision in identifying these conditions, enabling the issuance of alerts and the implementation of preventive measures with a high efficacy rate. Such actions reduce patients' health risks, allowing real-time detection and remote communication of vital signs to healthcare professionals.
GROWTH PARAMETER ESTIMATES OF SEVEN SMALL INDIGENOUS FISH SPECIES FROM THE FOUR SELECTED FLOODPLAIN WETLANDS OF NORTH BIHAR, INDIA
Authors: RAUT SHAILENDRA MOHAN , SINGH JASPREET , KUMAR MANOJ , SARMA KAMAL , SINGH INDU SEKHAR , GUPTA NISHIKANT , RAMTEKE KARANKUMAR KUMAR , SHARNAPPA MOGALEKAR HAVAGIAPPA , SINGH MUKESH KUMAR 
Published: January 2025

Morphometric study of length-weight relationship (LWR) and condition factors (K) of selected seven fish species from the floodplain wetland ecosystem of North Bihar. In the present investigation, 656 fishes (four families and seven species) out of 1426 fish samples were examined from floodplain wetlands of North Bihar, India. The fish species were captured by local fishing gear (such as cast net, drag net, and bamboo traps) during June 2019 to January 2020. Salmostoma bacaila and Puntius shophore were the most abundant while Trichogaster fasciata and Esomus danricus constituted the least count in the fish catch. Length weight relationship’s b values varied from 0.72 to 3.24. The values of b indicated negative and positive allometric growth patterns, while the K values ranged between 0.80 and 1.28. Among the captured species Salmostoma bacaila, Esomus danricus, and Anabas testudineus recorded negative allometric growth (b<3) whose body shape tended to be thinner. It might be attributed to unsuitable habitat conditions for the developmental growth of these fishes. Current study provided the baseline data about LWR and K of fish species from the floodplain wetlands of Bihar, India. This biological parameter of fish species could help in ecosystem-based fisheries management system (EBFM) by avoiding juvenile fishing, minimizing mesh size, improving selective gear properties, and restricting explosion/chemicals in the flood plain ecosystem.
Editorial
Authors: Muzaddadi Dr. Armaan U. 
Published: January 2025

We have been witnessing the degradation of natural ecosystems including wetlands, rivers, cultivable lands, forests, etc. in our surroundings which have become substantially visible during our life time. The rivers are drying up, the peripheries of the wetlands are being encroached, the construction of roads and urbanization have been making permanent detrimental effects to the natural ecosystems, indiscriminate dumping of pollutants into the water bodies has become rampant and so on. A classic example is the Pulicat lake in Andhra Pradesh and Tamil Nadu. This lake was cut across in the middle by the Sriharikota Link Road, which divided the water body into lagoon and marshy land. Such degradations of natural ecosystem are serious issues not only for India but also for the whole world. Usually, we barely see the policy makers taking bold steps to address these issues. Nevertheless, the European Union (EU), in this context, came forward and showed the path to the whole world by taking the long-awaited bold step. The Nature Restoration Law (NRL) has been adopted by the EU's Environmental Council on June 17, 2024. This is the law that aims to restore the health of Europe's natural ecosystems, mandating that at least 20% of the EU's land, sea, wetlands, rivers, forests areas must be restored by 2030 with a goal that all the ecosystems (in need of restoration) will be fully restored by 2050. Being a part of the EU's Biodiversity Strategy for 2030 and the European Green Deal, NRL focuses on the ecosystems including forests, agricultural lands, rivers, urban spaces, lakes etc. with specific measures such as the restoration of 25,000 km of rivers into free-flowing rivers and planting 3 billion additional trees by 2030. Undoubtedly, this is an inspiring and landmark law which must be imitated by not only India but also by rest of the world.