bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pseudophakic macular edema in nondiabetic and diabetic patients without diabetic retinopathy treated with intravitreal dexamethasone implant
Authors: Rodrigues Magna Vanessa , Garcia Jose Mauricio Botto , Pacheco Katia Delalibera , Borges Fabricio Tadeu , Isaac David Leonardo Cruvinel , Avila Marcos 
Published: September 2023

Abstract
Background
The purpose of this study was to compare the impact of intravitreal dexamethasone (DEX) implant during a 12-month period in nondiabetic and diabetic patients without diabetic retinopathy (DR) as a treatment for refractory pseudophakic cystoid macular edema (PCME) following prior treatment with topical nepafenac 0.1% and prednisolone 1%.

Methods
Forty-two consecutive medical records of patients diagnosed with PCME after uneventful cataract surgery were included. The outcomes measured included best corrected visual acuity (BCVA) and central foveal thickness (CFT). Linear regression analysis was statistically applied.

Results
Following topical treatment, nondiabetic and diabetic subjects presented a mean ± SD gain of − 0.11 ± 0.11 and − 0.18 ± 0.11 BCVA logMAR and a CFT reduction of − 43.42 ± 53.66 µm and − 58.76 ± 36.28 µm, respectively. The mean BCVA gain at month 12 subsequent to DEX implantation was − 0.35 ± 0.17 in nondiabetic (p < 0.001) and − 0.55 ± 0.26 in diabetic patients (p < 0.001), with CFT reductions of − 195.71 ± 93.23 µm (p < 0.001) and − 260.81 ± 198.69 µm (p < 0.001), respectively. Patients who responded with better VA after topical treatment presented better visual outcomes at month 12 following DEX implantation (r2 = 0.46; rho = − 0.71, p < 0.01).

Conclusion
Nondiabetic and diabetic patients without DR demonstrated similar results after DEX implant after combined topical therapy, suggesting that selected diabetic patients may have a response comparable to that of nondiabetic patients with PCME.
Anesthetic management for renal transplant in patients with grade III diastolic dysfunction: case reports
Authors: Kapoor Hemlata , Sarin Bipan Chander , Shah Milin Raju 
Published: September 2023

Abstract
Background
Left ventricular diastolic dysfunction is frequently noticed in patients with multiple co-morbidities. Echocardiography is used to determine the presence of diastolic dysfunction and to grade its severity. In left ventricular diastolic dysfunction, the ventricular diastolic distensibility, filling, or relaxation is abnormal; however, the left ventricular ejection fraction may be normal or decreased.

Case presentation
We present anesthetic management of two patients with diastolic dysfunction grade III for renal transplant. During declamping in renal transplant, high central venous pressures are required for adequate perfusion of the transplanted kidney. In the operation theater standard monitors including NIBP, SpO2 and five lead ECG were attached. An arterial line (radial) and central line (right internal jugular) were established for IBP and CVP monitoring. Infusions of furosemide and dopamine were started. Nitrogycerine and milrinone infusions were prepared but were not required intraoperatively. Both the patients were extubated at the end of surgery.

Conclusions
Increased incidence of major adverse cardiovascular events has been reported in surgical patients having grade III diastolic dysfunction. Hemodynamic instability and fluid overload in this set of patients are known to generate pulmonary edema.
Direct and indirect effects of fire on germination of shortleaf pine seeds
Authors: Fillingim Hope , Knapp Benjamin O. , Kabrick John M. , Stambaugh Michael C. , Elliott Grant P. , Dey Daniel C. 
Published: September 2023

Abstract
Background
Shortleaf pine is a fire-adapted tree species, and prescribed fire is commonly used to increase its regeneration success, improve wildlife habitat, and reach conservation objectives associated with open forest ecosystems. We studied direct effects of heat and smoke on shortleaf pine germination in a greenhouse study and effects of season of burning on the number of new germinants in a field study. Improved understanding of fire effects on shortleaf pine seed and regeneration success can help refine burn prescriptions to better meet specific management objectives.

Results
Temperatures ≥ 120 °C eliminated germination of shortleaf pine seeds in a greenhouse trial, and exposure of seeds to 60 °C resulted in no reduction in germination compared to the unheated control regardless of duration of exposure. At 80 °C, duration of heat exposure mattered, with exposure for 10 min reducing germination compared to unheated controls. Smoke exposure had no effect on germination. A field experiment showed that fall burns (prior to seedfall) resulted in greater initial germinant counts than early spring burns (after seedfall but before germination) or unburned controls, which both resulted in greater initial germinant counts than late spring burns (after germination).

Conclusions
Season of prescribed burning can affect the success of shortleaf pine germination. Late spring burning resulted in high mortality of young germinants. Burning in early spring likely resulted in direct damage to some seeds due to heating but may have also had indirect benefit by exposing mineral soil. Fall burning, before the dispersal of shortleaf pine seed, yielded the highest germinant count and is recommended if improving natural regeneration from seed is the primary objective.
Using normalisation process theory for intervention development, implementation and refinement in musculoskeletal and orthopaedic interventions: a qualitative systematic review
Authors: Carter Hayley , Beard David , Harvey Alison , Leighton Paul , Moffatt Fiona , Smith Benjamin , Webster Kate , Logan Pip 
Published: September 2023

Abstract
Background
Normalisation process theory (NPT) provides researchers with a set of tools to support the understanding of the implementation, normalisation and sustainment of an intervention in practice. Previous reviews of published research have explored NPT’s use in the implementation processes of healthcare interventions. However, its utility in intervention research, specifically in orthopaedic and musculoskeletal interventions, remains unclear. The aim of this review is to explore how NPT (including extended NPT, ENPT) has been used in orthopaedic/musculoskeletal intervention research.

Methods
A qualitative systematic review was conducted. Two bibliographic databases (Scopus and Web of Science) and a search engine (Google Scholar) were searched for peer-reviewed journal articles citing key papers outlining the development of NPT, related methods, tools or the web-based toolkit. We included studies of any method, including protocols, and did not exclude based on published language. A data extraction tool was developed, and data were analysed using a framework approach.

Results
Citation searches, of the 12 key studies, revealed 10,420 citations. Following duplicate removal, title, abstract and full-text screening, 14 papers from 12 studies were included. There were 8 key findings assessed against GRADE-CERQual (Confidence in Evidence from Reviews of Qualitative research). Five were of high confidence supporting NPT/ENPT’s use in the implementation process for interventions targeting a range of MSK/orthopaedic conditions. NPT/ENPT offers a useful analytical lens to focus attention and consider implementation factors robustly. There is limited evidence for the selection of NPT/ENPT and for the use of the Normalisation Measure Development instrument. Three findings of moderate confidence suggest that coherence is seen as a fundamental initial step in implementation, there is limited evidence that study population limits NPT’s utility and the application of ENPT may pose a challenge to researchers.

Conclusion
This review demonstrates NPT’s utility in supporting intervention implementation for orthopaedic and musculoskeletal conditions. We have theorised the benefits ENPT offers to intervention development and refinement and recommend future researchers consider its use. We also encourage future researchers to offer clear justification for NPT’s use in their methodology.

Trial registration
The review protocol is registered with PROSPERO (CRD42022358558).
Assessing the expression of differentiation antagonizing non-protein coding RNA (DANCR) in newly diagnosed Egyptian acute myeloid leukemia patients
Authors: Rasheed Nour Mohammed , Nounou Howaida Attia , Eltabakh Soad Mohamed , Hamed Nahla A. M. , Darwish Ayman Ahmed 
Published: September 2023

Abstract
Background
Role of Long non-coding RNAs in cancer research in the recent years have been highlighted with evidence to their involvement in cancer disease pathogenesis and progression. One of these emerging long non-coding RNAs is differentiation antagonizing non-protein coding RNA (DANCR). DANCR distinct expression in different cancers and implication in tumor signaling pathways made it a promising therapeutic target for cancer.
The purpose of this study was to evaluate DANCR expression in de novo acute myeloid leukemia (AML) patients and to assess DANCR expression in relation to cytogenetics and French American British (FAB) AML classification as well as correlate DANCR expression with patients’ response to treatment.
The present study included 60 newly diagnosed AML patients and 30 healthy subjects as controls. Relative DANCR expression was done using real time qPCR method.

Results
DANCR was significantly downregulated in AML patients compared to controls (p = 0.038). In addition, DANCR showed significantly lower expression in M4 and M5 compared to M0, M1, and M2 groups (p < 0.001). Furthermore, DANCR expression was significantly downregulated in cytogenetically normal AML patients compared to the controls (p = 0.011).

Conclusion
Significant downregulation of DANCR in AML suggests a potential tumor suppressor role and variable expression of DANCR among AML subtypes suggests that DANCR action may be different among AML subtypes. Also, M1 subtype patients with higher DANCR expression were less refractory to treatment and therefore less resistant to cytarabine.
Perspective on the spatio-temporal spread of epidemics in metapopulation networks
Authors: Wang Jianbo , Du Zhanwei , Li Hui-Jia , Wang Lei , Xu Xiao-Ke , Wang Zhen , Wang Lin , Li Xiang 
Published: September 2023

Abstract
We review the recent progress of epidemic dynamics in metapopulation networks. Firstly, we give an introduction of the concepts about epidemic models and metapopulation network. Then, the theoretical characterization of epidemics spread in metapopulation networks is summed up. The measures of how to curb the spread of epidemics are summarized. The applications of inferring epidemic pathways based on epidemic data and reconstruction of epidemic transmission by phylogeographic are introduced. Finally, we present the outlooks about further research of epidemic dynamics on metapopulation networks.
Exploring the perspectives of transwomen on ethical issues in conducting research with the transwomen community in India: A qualitative enquiry
Authors: Yatirajula Kanaka Sandhya , Mukherjee Ankita , Giri Santosh , Maulik Pallab K 
Published: September 2023

Background: Research with or involving transwomen in India is limited; previous research has focused on understanding the problems and discriminations they face. However, no studies have focused on exploring the ethical dimension of conducting research among transwomen. This kind of research is important for true representation but is only possible when cis-gender researchers engage with transgender perspectives. The study aimed at identifying the perspective of transwomen regarding the need to undertake research among them, understanding their perspectives of research ethics and articulating requirements to ensure their inclusion in research. Methods: The study was an exploratory study using qualitative research methods, conducted with transwomen in Kolkata, West Bengal, India, in collaboration with a transgender led community-based organisation. The National Ethical Guidelines for Biomedical and Health Research involving Human Participants by the India Council for Medical Research was the reference point for this exploration with focus on select research ethics principles and allied ethical aspects. Results: Insights into the perspectives of the transwoman from this research include: research among transgender persons is much needed to understand the trans way of life, identify problems and possible solutions; researchers should be mindful of the preferred nomenclature, invest in rapport building; ensure research is done in a safe space; the results are reported in a way that does not increase stigma and the research findings are used for the benefit of the community. Conclusions: While conducting research among trans-communities is important, it is essential that before starting any research with transgender persons, researchers should carefully examine questions related to who benefits from the proposed research, whether the proposed study is meaningful to the trans-community, whether it address their immediate and pressing needs and finally whether it furthers the stigma that transgender persons are subjected to, before embarking on the study.
ECOLINGUISTIC APPROACH TO THE STUDY OF MODERN ELECTRONIC BUSINESS COMMUNICATION
Authors: Vorobyova Anna E. , Doborovich Anna N. , Kuznetsova Elena V. 
Published: September 2023

Background. Electronic business communication is a complex and multifaceted subject for scientific research, since it operates in a specific computer-mediated environment that is characterized by dynamic development. In this regard, there is a need to develop the study of this linguistic phenomenon at the nexus of various scientific paradigms. Human society is continuously evolving and becoming more complex, which directly affects the language that society uses as one of its codes. Due to the improvement of information technologies in modern electronic business interaction, we can register significant changes in the lexical content, clichés typical of the officialese, and features of syntactic constructions. Considering the fact that electronic business communication determines the social and cultural specifics of the modern world business community, it seems relevant to study this form of speech from the ecolinguistic perspective.
Purpose. The article deals with the linguistic and style-forming characteristics of modern electronic official business texts from the point of view of the linguo-ecological norm, and also examines the level of language digression in the genre of business e-mails.
Materials and methods. The empiric material for the study is represented by a corpus of 70 units of international business e-mails in English, provided by one of the commercial organizations in Belgorod. In the course of the research, a functional-dynamic approach to the object, methods of comparative, stylistic, pragmalinguistic analysis, as well as the method of free associative experiment were applied.
Results. The results of the study proved that the computer-mediated environment has a direct impact on the linguistic, structural and style-forming characteristics of official business electronic texts that function in this environment.
Conclusion. Business e-mails are marked by certain functional characteristics, stylistic variation and linguistic digression.
INVENTION OF “ROMAN”, IMAGINATION OF “BARBARIAN”: THE CONSTRUCTION OF THE IMPERIAL IDENTITY OF ROME IN THE LATER TEXTS OF OVID
Authors: Kyrchanoff Maksym W. 
Published: September 2023

Purpose. The author in the presented article considers the late texts of Ovid, presented by Tristia and Epistulae ex Ponto. The purpose of the article is to analyze how the texts reflect the processes of formation of the imperial political culture and identity.
Research novelty. The novelty of the study lies in the analysis of the late texts of Ovid not as literary, but as political narratives that inspired the transformation of Roman identity, contributing to the actualization of the concepts of Self and Otherness.
Materials and methods. Methodologically, the article is based on the principles of interdisciplinarity proposed in the framework of studies of nationalism, intellectual and cultural history, transplanted into the contexts of the literary history of Rome in the 1st century AD.
Results. The article analyzes 1) Ovid’s attempts to form an ideal and positive image of power, 2) Ovid’s contribution to the development of Roman ideas about barbarians, 3) peculiarities of Ovid’s geographical perception of the formation of Roman territory as an imperial heterogeneous space. The contribution of the later texts of Ovid, represented by Tristia and Epistulae ex Ponto and written in exile, to the formation of political imperial culture and identity is shown. The results of the study suggest that 1) Ovid was one of the first Roman authors who textualized the transformations of political power, contributing to the genesis of the cult of imperial power as an element of political culture; 2) in the formation and imagination of the images of the barbarians, Ovid continued the earlier tendencies of hierarchization and idealization of the inhabitants of the peripheral provinces: 3) the later texts of Ovid, written in exile, became a contribution to the development of the cultural geography of the emerging Roman Empire, based on the glorification and positive idealization of Italy through the prism of its opposition to the provinces.
BUREAUCRATISM AND THE FIGHT AGAINST IT IN THE YEARS OF PERESTROIKA ON THE PAGES OF THE NEWSPAPER “KIROVSKAYA PRAVDA”
Authors: Lobanov Denis I. 
Published: September 2023

Background. The glasnost policy pursued in the USSR in the second half of the 1980s made it possible to weaken censorship restrictions. At party conferences, in newspapers, television programs, previously forbidden topics began to be raised. One of them is the spread of bureaucracy in the organs of power in the Soviet Union. The fight against this phenomenon in the Soviet Union during the years of perestroika was practically not considered as a phenomenon in post-Soviet historiography within the Kirov region. The paper analyzes the articles of the newspaper “Kirovskaya Pravda”, condemning bureaucracy. The headings that highlighted the negative impact of red tape on society were studied.
Purpose. Consider and analyze the articles of the newspaper “Kirovskaya Pravda” of the perestroika period, which denounce bureaucracy.
Materials and methods. The basis for the study was the archival materials of the Central State Archive of the Kirov Region and the issue of the newspaper “Kirovskaya Pravda” – the organ of the Kirov Regional Committee of the CPSU and the Regional Council of People’s Deputies in the period under review. When analyzing sources, the method of content analysis was used.
Results. The appearance in the newspaper “Kirovskaya Pravda” of columns devoted to exposing bureaucracy in the Kirov region was associated with the political trend set by M. S. Gorbachev in 1986. Most of the articles published in the periodical within the framework of sections “Bureaucratism - out of the way” and “Addresses of red tape”, were associated with complaints from tenants of apartment buildings about the work of housing and communal services enterprises. The reason for the irregular publication of articles was a change in the interest of the country’s leadership in this topic. The results of the content analysis allow us to conclude that both headings that denounced formalism contained similar stories of residents of the Kirov region who faced bureaucracy. The problems associated with the sphere of housing and communal services were the basis for articles related to red tape.
Practical implications. The results of the study can be used to study the phenomenon of “bureaucracy” during the years of perestroika.
“THE PAN-ROMANCE STATE” AS AN INVENTED HISTORIOGRAPHICAL TRADITION IN THE INTELLECTUAL HISTORY OF ROMANCE PHILOLOGY
Authors: Kyrchanoff Maksym W. 
Published: September 2023

Purpose. The purpose of this study is to analyze the perception of the common pan-Romance state in the intellectual history of Romance philology. The author analyzes various viewpoints on the common pan-Romance state, including the arguments of supporters and opponents of its existence.
Novelty. The novelty of the study lies in the analysis of interpretations of the common pan-Romance state in contexts of the history of the Romance languages through the prism of intellectual history and the history of ideas.
Materials and methods. Methodologically, the article is based on the principles of interdisciplinary historiography proposed in intellectual and cultural history, which allows us to analyze the problems of the common pan-Romance state as part of the history of ideas and an invented historiographic tradition or intellectual construct.
Results. The article analyzes 1) the arguments of supporters of the existence of a common Romance state as a stage between Latin and Romance languages, 2) the ideas of critics and opponents of the idea of a common Romance state, who tend to look for the origins of the Romance languages directly in Latin, 3) the possibilities and potency of revising early viewpoints in contexts the history of late Latin and the early genesis of the Romance languages. The article also analyzes 1) the arguments of supporters and opponents of the existence of the common Romance state through the prism of intellectual history and the history of ideas, 2) the history of Romance philology through the prism of the archaeology of ideas, which allows us to trace how the arguments of supporters and opponents of the common Romance state have changed, 3) the general logic of the development of Romance philology through the prism of the transformation of ideas about the general Romance state.
Conclusions. The results of the study suggest that 1) ideas about the common Romance state in the history of Romance linguistic became a common historiographic place, turning into an invented intellectual and historiographical tradition, 2) discussions and debates about the existence or absence of a general Romance state stimulated the search for new ideas, contributing to the development of Romance philology, 3) the controversy and debatability of the concept of the general Romance state in the history of Romance philology will remain a factor contributing to intellectual discussions and actualization of the role of revisionism as a universal factor in the development of modern interdisciplinary linguistics.
ON SYNONYMS IN THE EPIC TALES OF THE OKHOTSK EVENS
Authors: Nesterova Elena V. 
Published: September 2023

Background. The Even language is among the endangered languages. The situation requires comprehensive research, recording and documentation of the Even language and culture. The research of the synonymic relations in the Even language will show the lexical-semantic development of the Even word, the stylistic features of the language.
Purpose. The article is devoted to the study of synonyms in the Even folk texts.
Materials and methods. Epic tales of the Evens of Okhotsk are used as a source of research. The main method of research is the descriptive one along with semantic analysis and elicitation methods.
Results. The collected lexical material, distributed according to the parts of speech, reveals a numerical superiority of verbal synonyms in comparison with other groups of words. In the texts of the narrator N.G Mokrousov. synonyms serve as expressive means, have expressive load, are used in the description of the various phenomena, properties, actions, are applied with a view of preservation of a rhythm of singing. Frequent synonyms are recorded in the work.
Practical implications. The results of the work can be applied in studies on the language and folklore of the Tungus-Manchur peoples.