bluuebunny/crossref_metadata_2025_split huggingface dataset:
Profile of Hypertensive Patients Indicated to Surgical Procedures in The Oral Cavity
Authors: Borja de Melo Téssia Richelly Nóbrega , Barros Freitas Dalva Zélia , Machado Patriota Irley Gonzaga , Rivera Giovani Amado , Araújo Flaviano Falcão de 
Published: April 2023

Objective: The present study aimed to evaluate the profile of hypertensive patients, indicated surgical procedures in the oral cavity.
Methods: Treated an observational and cross-sectional research, with a quantitative approach, whose sample consisted of 50 medical records of patients diagnosed with arterial hypertension. A survey was conducted at the Clinical School of the University Center of Patos - UNIFIP / PB. Data collection was performed by a single examiner. The information was distributed on the form prepared for this purpose. The data were computed using the SPSS software for Windows, v. 22, and analyzed by descriptive statistics that use as frequencies, media and standard deviations.
Results: The average age of the patients was 48 years. The majority of the sample was composed of women (58%); by white patients (40%); non-smoking patients (52%) and ex-alcoholics (36%). As for diseases associated with hypertension, diabetes was more prevalent (18%), being also the most frequent among the variations associated with family history (20%). The drug most used by patients was Losartana (34%); and the local dental anesthetic, a 2% Mepivacaine associated with Epinephrine 1,100.00 (56%). Most patients were seen in the morning shift (58%).
Conclusions: It was concluded that white non-smoking women and ex-alcoholics were more prevalent among hypertensive patients, with diabetes being a disease more associated with arterial hypertension.
Cloud height and thickness measurement based on a superconducting nanowire single-photon detector
Authors: Gao Tianquan , Feng Jiali 
Published: April 2023

At present, the methods for measuring cloud height and thickness mainly include using micro-pulse lidar and microwave radiometer data. To further study cloud height and thickness, a superconducting nanowire single-photon detector (SNSPD) is applied to a lidar system for the first time, to the best of our knowledge, to analyze the cloud height and thickness. In the experiment, a 1.2-m-diameter horizon telescope is used for laser emitting and echo receiving, a 1064 nm near-IR pulse laser with a single pulse energy of 4 mJ is used as the system emission laser, and a 4-pixel SNSPD array detector is used as the end receiver to complete the echo photon reception. By analyzing the experimental data, the distributions of cloud height and cloud thickness can be obtained using the laser ranging system. The cloud cover condition on a certain day was measured, and the obtained cloud bottom height was about 1222 m, cloud top height was about 1394 m, and cloud cover thickness was about 172 m. The difference between the cloud cover thickness and the forecast value was 28 m. The cloud cover height and thickness measured by this method are true and credible.
Dynamics of a dispersion-tuned swept-fiber laser
Authors: Li Duidui , Yin Guolu , Huang Ligang , Gao Lei , Dang Laiyang , Zhang Zeheng , Huang Jingsheng , Lu Huafeng , Zhu Tao 
Published: April 2023

In this paper, we studied the dynamics of a dispersion-tuned swept-fiber laser both experimentally and theoretically. By adding a dispersion compensation fiber and an electro-optic modulator in the laser cavity, an actively mode-locked laser was obtained by using intensity modulation, and wavelength sweeping was realized by changing the modulation frequency. Using a high-speed real-time oscilloscope, the dynamic behaviors of the swept laser were investigated during wavelength switching, static-sweeping cycle, and continuous sweeping, respectively. It was found that the laser generates relaxation oscillation at the start of the sweeping mode. The relaxation oscillation process lasted for about 0.7 ms, and then the laser started to operate stably. Due to the nonlinear effect, new wavelengths were generated in the relaxation oscillation process, which is not beneficial for applications. Fortunately, relaxation oscillation disappears if the laser starts up and operates in the continuous sweeping mode, and the good sweeping symmetry between the positive sweep and negative sweep increases the application potential of the laser. In addition, the instantaneous linewidth is almost the same as that in the static state. These results describe the characteristics of the laser from a new perspective and reveal, to the best our knowledge, the intensity dynamics of such lasers for the first time. This paper provides some new research basis for understanding the establishment process of dispersion-tuned swept-fiber lasers and their potential application in the future.
Early changes in immunoglobulin G levels during immune checkpoint inhibitor treatment are associated with survival in hepatocellular carcinoma patients
Authors: Balcar Lorenz , Bauer David , Pomej Katharina , Meischl Tobias , Mandorfer Mattias , Reiberger Thomas , Trauner Michael , Scheiner Bernhard , Pinter Matthias 
Published: April 2023

Background & aims
Immunotherapy represents the new standard of care in systemic first-line treatment of hepatocellular carcinoma (HCC). Biomarkers that predict treatment response and survival remain an unmet clinical need.

Methods
Patients with HCC treated with immune-checkpoint inhibitors (ICI) between 10/2017 and 03/2022 were retrospectively evaluated. Immunoglobulin levels (IgG, IgM, IgA) were measured at baseline and six weeks after initiation of ICI treatment. Impact of relative changes on overall survival (OS), progression-free survival (PFS), and time to progression (TTP) were evaluated.

Results
Seventy-two patients with HCC receiving ICI (mostly atezolizumab/bevacizumab n = 54,75%) were included (mean age: 68±12 years, cirrhosis: 72%, mean Child-Turcotte-Pugh [CTP] score: 7±2 points). Most patients had a preserved performance status (ECOG-PS 0, n = 45, 63%), 25 (35%) showed macrovascular invasion, and 32 (44%) had extrahepatic spread.
Baseline immunoglobulin values (median, IgG: 1395mg/dL, IgM: 337mg/dL, IgA: 89mg/dL) were not different between responders and non-responders, and neither baseline nor follow-up immunoglobulin values correlated with OS, PFS, and TTP. However, the relative change in IgG (Δ-IgG) independently predicted OS in multivariable Cox regression analysis after adjusting for severity of liver disease, baseline AFP and CRP as well as for Δ-IgA and Δ-IgM. Patients could be stratified into high (Δ-IgG≥+14%) vs. low (Δ-IgG<+14%) risk groups (median OS: 6.4 vs. 15.9 months; p = 0.001). Importantly, Δ-IgG was also associated with PFS and TTP on adjusted multivariable Cox regression analyses.

Conclusion
Our study proposes a higher increase of Δ-IgG upon ICI treatment as a negative prognostic marker in patients with HCC, independent of underlying liver disease severity. These results require independent validation.
Malnutrition as a major related factor of frailty among older adults residing in long-term care facilities in Korea
Authors: Moon SeolHwa , Oh Eunmi , Chung Daum , Choi Rina , Hong Gwi-Ryung Son 
Published: April 2023

Objectives
The objectives of this study were 1) to investigate the prevalence and co-existence of frailty and malnutrition and 2) to identify factors related to frailty (including malnutrition) according to the level of frailty.

Methods
Data collection was conducted from July 11, 2021, to January 23, 2022, in 558 older adults residing in 16 long-term care facilities (LTCFs) in Korea. The FRAIL-NH and Mini-Nutritional Assessment short form were used to measure frailty and nutrition, respectively. The data analysis included descriptive statistics and a multivariate logistic regression.

Results
The mean age of the participants was 83.68 (± 7.39) years. Among 558 participants, 37 (6.6%), 274 (49.1%), and 247 (44.3%) were robust, prefrail, and frail, respectively. At the same time, 75.8% were categorized as having malnutrition status (malnourished: 18.1%; risk of malnutrition: 57.7%), and 40.9% had co-existing malnutrition and frailty. In the multivariate analysis, malnutrition was identified as the major frailty-related factor. Compared with a normal nutritional status, the incidence of frailty in the malnutrition group was 10.35 times (95% CI: 3.78–28.36) higher than the incidence of robustness and 4.80 times (95% CI: 2.69–8.59) higher than the incidence of prefrail.

Conclusion
The prevalence of frailty and malnutrition, and their co-existence, among older adults residing in LTCFs was high. Malnutrition is a major factor that increases the incidence of frailty. Therefore, active interventions are needed to improve the nutritional status of this population.
Relationships between total reserve and financial indicators of Bangladesh: Application of generalized additive model
Authors: Salan Md. Sifat Ar , Naznin Mahabuba , Pandit Bristy , Sumon Imran Hossain , Hossain Md. Moyazzem , Kabir Mohammad Alamgir , Majumder Ajit Kumar 
Published: April 2023

BackgroundThe reserve of a country is a reflection of the strength of fulfilling its financial liabilities. However, during the past several years, a regular variation of the total reserve has been observed on a global scale. The reserve of Bangladesh is also influenced by several economic and financial indicators such as total debt, net foreign assets, net domestic credit, inflation GDP deflator, net exports (% of GDP), and imports of goods and services (% of GDP), as well as foreign direct investment, GNI growth, official exchange rate, personal remittances, and so on. Therefore, the authors aimed to identify the nature of the relationship and influence of economic indicators on the total reserve of Bangladesh using a suitable statistical model.Methods and materialsTo meet the objective of this study, the secondary data set was extracted from the World Bank’s website which is openly accessible over the period 1976 to 2020. Moreover, the model used the appropriate splines to describe the non-linearity. The performance of the model was evaluated by the Akaike information criterion (AIC), Bayesian information criterion (BIC), and adjusted R-square.ResultsThe total reserve of Bangladesh gradually increased since 2001, and it reached its peak in 2020 which was 43172 billion US dollars. The data were first utilized to build a multiple linear regression model as a base model, but it was later found that the model has severe multicollinearity problems, with a maximum value of VIF for GNI of 499.63. Findings revealed that total debt, inflation, import, and export are showing a non-linear relationship with the total reserve in Bangladesh. Therefore, the authors applied the Generalized Additive Model (GAM) model to take advantage of the nonlinear relationship between the reserve and the selected covariates. The overall response, which is linearly tied to the net foreign asset in the GAM model, will change by 14.43 USD for every unit change in the net foreign asset. It is observed that the GAM model performs better than the multiple linear regression.ConclusionA non-linear relationship is observed between the total reserve and different economic indicators of Bangladesh. The authors believed that this study will be beneficial to the government, monetary authorities also to the people of the country to better understand the economy.
Verhaltensentscheidungen für das automatische Fahren an innerstädtischen T-Kreuzungen mittels ereignisdiskreter Systeme
Authors: Weinreuter Hannes , Strelau Nadine-Rebecca , Deml Barbara , Heizmann Michael 
Published: April 2023

Zusammenfassung
Eine der Herausforderungen vor der Einführung des automatischen Fahrens sind nicht signalisierte innerstädtische Kreuzungen. Dort kann es zu nicht eindeutig geregelten Verklemmungssituationen kommen. Die Beteiligten müssen in diesem Fall miteinander kooperieren, was für automatische Fahrzeuge eine Herausforderung darstellt. Der vorgestellte Algorithmus ist in der Lage, eine Verhaltensentscheidung für eine automatische Fahrzeugführung zu treffen. Die Entscheidung ist abhängig von der Situation und dem Verhalten der übrigen Verkehrsteilnehmer. Das Modell ist als ereignisdiskretes System modelliert, dies ist insbesondere im Hinblick auf die Nachvollziehbarkeit der Entscheidungen von Vorteil. Der Algorithmus wird mitsamt der verwendeten Eigenschaften und der definierten Ereignisse ausführlich vorgestellt und anhand einer Simulation auf Karten realer Kreuzungen validiert.
Investigating the limestone quarries as geoheritage sites: Case of Mardin ancient quarry
Authors: Karataş Lale , Alptekin Aydın , Yakar Murat 
Published: April 2023

AbstractAbandoned quarries are valuable as a tourism element, as they exhibit the building material of the buildings built in the geographical area they are located in as historical objects. However, in order to determine how the quarries can be used for tourism purposes, it is necessary to determine the constraints on the choice of solution in spatial arrangements. The aim of this study is to investigate how the ancient limestone quarry of Mardin, which is a natural and cultural geological heritage, can be used for tourism and to develop suggestions. Within the scope of the study, in order to examine the possibilities of how an idle quarry located in Mardin province in Turkey can be used for tourism, the constraints in the selection of the post-use solution will be determined. In order to determine whether the Mardin quarry is accessible and safe to visit, various field studies were carried out in the study area, laboratory experiments and analyses. The caves were scanned with a 3D laser scanner, and its plans and sections were obtained. The findings were evaluated and suggestions were developed for the use of the ancient limestone quarry for tourism.
Gum tragacanth-mediated synthesis of metal nanoparticles, characterization, and their applications as a bactericide, catalyst, antioxidant, and peroxidase mimic
Authors: Kora Aruna Jyothi 
Published: April 2023

Abstract
Among biogenic methods employed for synthesizing various nanoparticles (NPs), gum tragacanth (TGC)-mediated NP production is important. The gum TGC not only qualifies the principles of green chemistry but also embraces unique qualities. In this perspective, the current review concentrates on the composition, uses, and exploitation of gum towards synthesizing metal NP of silver (Ag), gold (Au), palladium (Pd), platinum (Pt), and their characterization (UV-visible absorption spectroscopy, X-ray diffraction, Fourier transform infrared spectroscopy, and transmission electron microscopy). In addition, applications of synthesized NP as a bactericide, catalyst, antioxidant, and peroxidase mimic are emphasized. Ag NP (13 nm) showed antibacterial action against Gram-negative and Gram-positive bacteria at 2–12 μg‧mL−1. The exploitation of Ag NP as a bactericide makes it a candidate of choice for medicinal and pharmacological applications. The catalytic activity of Pd NP (14 nm) demonstrated borohydride reduction of methylene blue. The gum reduced/capped metal and metal oxide NP serve as redox and photocatalysts for the remediation of toxic pigments and dyes in industrial effluents. At 15 μg‧mL−1, Pd NP exhibited 1,1-diphenyl-2-picrylhydrazyle radical scavenging activity (95.8%) and served as an artificial enzyme mimic for colorimetric sensing of hydrogen peroxide. The industrial applications of other TGC-based nanocomposites, such as heavy metal sorption, wound dressing, drug carrier, tissue engineering, etc., are mentioned.
Quantum-enhanced interferometer using Kerr squeezing
Authors: Kalinin Nikolay , Dirmeier Thomas , Sorokin Arseny A. , Anashkina Elena A. , Sánchez-Soto Luis L. , Corney Joel F. , Leuchs Gerd , Andrianov Alexey V. 
Published: April 2023

Abstract
One of the prime applications of squeezed light is enhancing the sensitivity of an interferometer below the quantum shot-noise limit, but so far, no such experimental demonstration was reported when using the optical Kerr effect. In prior setups involving Kerr-squeezed light, the role of the interferometer was merely to characterize the noise pattern. The lack of such a demonstration was largely due to the cumbersome tilting of the squeezed ellipse in phase space. Here, we present the first experimental observation of phase-sensitivity enhancement in an interferometer using Kerr squeezing.
Impact of Acute Visual Experience on Development of LGN Receptive Fields in the Ferret
Authors: Stacy Andrea K. , Schneider Nathan A. , Gilman Noah K. , Van Hooser Stephen D. 
Published: April 2023

Selectivity for direction of motion is a key feature of primary visual cortical neurons. Visual experience is required for direction selectivity in carnivore and primate visual cortex, but the circuit mechanisms of its formation remain incompletely understood. Here, we examined how developing lateral geniculate nucleus (LGN) neurons may contribute to cortical direction selectivity. Usingin vivoelectrophysiology techniques, we examined LGN receptive field properties of visually naive female ferrets before and after exposure to 6 h of motion stimuli to assess the effect of acute visual experience on LGN cell development. We found that acute experience with motion stimuli did not significantly affect the weak orientation or direction selectivity of LGN neurons. In addition, we found that neither latency nor sustainedness or transience of LGN neurons significantly changed with acute experience. These results suggest that the direction selectivity that emerges in cortex after acute experience is computed in cortex and cannot be explained by changes in LGN cells.SIGNIFICANCE STATEMENTThe development of typical neural circuitry requires experience-independent and experience-dependent factors. In the visual cortex of carnivores and primates, selectivity for motion arises as a result of experience, but we do not understand whether the major brain area that sits between the retina and the visual cortex—the lateral geniculate nucleus of the thalamus—also participates. Here, we found that lateral geniculate neurons do not exhibit changes as a result of several hours of visual experience with moving stimuli at a time when visual cortical neurons undergo a rapid change. We conclude that lateral geniculate neurons do not participate in this plasticity and that changes in cortex are likely responsible for the development of direction selectivity in carnivores and primates.
From resin formulation and process parameters to the final mechanical properties of 3D printed acrylate materials
Authors: Schittecatte Laura , Geertsen Valérie , Bonamy Daniel , Nguyen Thuy , Guenoun Patrick 
Published: April 2023

AbstractPhotopolymerizable resins are increasingly used to generate complex 3D printed parts through stereo lithography, digital light processing (DLP) and liquid crystal display (LCD) 3D printing. Many challenges relating to the resin chemistry and printing parameters still exist and must be addressed in order to entirely control the properties of parts after printing. This work reviews the current knowledge and describes the potential of DLP/LCD methods for printed acrylate resins, as well as the steps necessary to achieve a better control over the mechanical properties of printed materials.
Graphical abstract
EFEITO ALELOPÁTICO DO EXTRATO DE Baccharis articulata EM SEMENTES E PLÂNTULAS DE Luffa cylindrica
Authors: Schoffel André , Koefender Jana , Camera Juliane Nicolodi 
Published: April 2023

A bucha vegetal possui múltiplas aptidões industriais e sua interação com substâncias alelopáticas de outras espécies é importante para definições de estratégias de manejo e também na busca de alternativas de controle para invasoras em cultivos orgânicos. O objetivo desta pesquisa foi avaliar o efeito do extrato bruto aquoso de carqueja sobre a germinação e crescimento de plântulas de bucha vegetal. A germinação das sementes foi testada pelo método do rolo de papel com 25 sementes devidamente distanciadas sobre cada papel de germinação. O delineamento experimental foi o inteiramente casualizado, com quatro repetições e os tratamentos foram compostos pelas concentrações de extrato de carqueja (zero; 25; 50; 75 e 100 g L-1). As avaliações foram realizadas aos quatro e aos 14 dias após a instalação do teste. Foram avaliados os percentuais de plântulas anormais, germinação e vigor, o comprimento de parte aérea e de raízes (cm), massa seca de cotilédones, hipocótilo e de raízes. Houve efeito alelopático negativo do extrato bruto aquoso da parte aérea de plantas de carqueja sobre a germinação e o vigor de sementes e no crescimento de plântulas de bucha vegetal.
CARACTERIZAÇÃO TECNOLÓGICA DE METAPIROXENITO DA FORMAÇÃO CÓRREGO DOS BOIADEIROS, NOVA LIMA (MG), BRASIL
Authors: Ferreira Bruno Trindade , Lima Rosa Malena Fernandes , Santos Maristella Moreira , Brito Hermando , Carmignano Ottavio Raul Domenico Riberti 
Published: April 2023

Rochas e minerais industriais são materiais aplicados na produção de uma grande variedade de produtos, usados pela sociedade moderna. Um mesmo mineral ou rocha industrial pode ter diversas aplicações, dependendo de suas propriedades físicas, mineralógicas e químicas. O presente estudo teve como objetivo efetuar a caracterização tecnológica de uma amostra de metapiroxenito, proveniente da formação Córrego dos Boiadeiros, localizado no Quadrilátero Ferrífero, MG (Brasil), visando verificar possíveis aplicações industriais para o mesmo. Fluorescência de raios X foi utilizada para determinar os teores dos seguintes óxidos: 0,06% TiO2, 8,2% Fe2O3, 24,1% MgO, 2,1% Al2O3, 48,7% SiO2 e 1,8% CaO. Na caracterização mineralógica por difração de raios X, microscopia ótica, MEV/EDS e termogravimetria foram identificados os seguintes minerais: antigorita, clorita, cromita, ilmenita, magnetita, rutilo, talco e tremolita. Para os testes preliminares de concentração, o material usado (-147?m) apresentou 32% de partículas na fração -37?m com d50 igual a 74?m. Para o campo magnético de 3575 Gauss e fração granulométrica -74?m a recuperação em massa foi de 96,4% e alvura igual a 61,9% para o produto não magnético. Embora os ensaios de separação magnética não tenham gerado concentrados enriquecidos em talco, os produtos não magnéticos apresentaram especificações para as seguintes aplicações: papel (papel de parede e embalagem), inseticida e fertilizante.
CARTOGRAFANDO CURRÍCULOS
Authors: De Pinho Rosilene Lopes , Maldonado Maritza Maciel Castrillon 
Published: April 2023

Este artigo é um convite a pensar currículos outros, a pensar o currículo como potência, como resistência, como fabulações que movimentam o ambiente escolar. Objetiva-se problematizar as relações entre o espaçotempo escolar, o currículo e crianças, que na imanência de suas infâncias, de suas afecções com o mundo virtual, criam narrativas audiovisuais no cotidiano escolar entre linhas de fugas e escapes. Como inspiração metodológica, utilizamos a cartografia para adentrar o espaçotempo de uma escola pública estadual do município de Cáceres-MT, perceber a relação entre escola, currículo, crianças e infâncias e fazer ressoar as .bonitezas, fabulações e criações curriculares de seus praticantespensantes. Apresentamos o resultado parcial de uma pesquisa de mestrado que acompanhou movimentos e encontros que acontecem nos espaçostempos escolares, que vão muito além de normatizações, na medida em que mostram linhas de escapes, resistências, brechas e fugas que fazem a escola, que criam currículos rizomáticos, currículos pensadospraticados com o cotidiano, currículos criados pelas crianças que produzem efeitos e singularidades outros