bluuebunny/crossref_metadata_2025_split huggingface dataset:
Distinct origin and fate for fetal hematopoietic progenitors
Authors: Soares-da-Silva F. , Nogueira G. , Mailhe Marie-Pierre , Freyer L. , Perkins A. , Hatano S. , Yoshikai Y. , Pereira P. , Bandeira A. , Elsaid R. , Gomez-Perdiguero E. , Cumano A. 
Published: January 2025

SummaryIt was proposed that two sequential sources of intraembryonic multipotent progenitors ensure blood cell production from late gestation into adulthood, with only the latter producing self-renewing hematopoietic stem cells (HSC). How these two populations differ and how they impact the establishment of the postnatal immune system, remains poorly understood. Using complementary lineage tracing models, we showed that the first emerging embryonic multipotent progenitors (eMPP) are responsible for late gestation hematopoiesis. They are distinct from HSC that do not significantly contribute to embryonic mature blood cells. eMPP are the predominant source of embryonic lymphocytes and lymphoid tissue inducer cells, some of which persist for life. Between E12.5 and E16.5 eMPP rapidly differentiate, whereas HSC expand 20-fold. Altogether, these results support the notion that eMPP establish the embryonic adaptive immune system and shape the lymphoid organs where later adaptive immune responses occur, while HSC expand to sustain blood cell production throughout life.
Optimization of Extraction Process by Response Surface Method-ology of Total Flavonoids fromZiziphus JujubeFlesh and its Sedative-Hypnotic Effects
Authors: Li Jie , Li Baojian , Shi Xinbo , Yang Yuangui , Song Zhongxing 
Published: January 2025

AbstractBackground & aimsThis study optimizes the extraction process of total flavonoids fromZiziphus jujubeflesh (TFZJF) by response surface methodology and investigating its sedative-hypnotic effects and mechanisms in a para-chlorophenylalanine (PCPA)-induced insomnia mouse model. It provides theoretical support for the further comprehensive utilization ofZiziphus jujubefruit and flesh.MethodsSingle-factor experiment and Box–Behnken response surface design were used to study the ethanol reflux extraction process of TFZJF, with flavonoid extraction rate as the indicator, to obtain the optimal extraction process of TFZJF. An insomnia model in mice was induced via an intraperitoneal injection of PCPA, and the effects of TFZJF on this model, along with its underlying mechanisms, were assessed using various approaches, including sodium pentobarbital-induced sleep potentiation, HE staining of tissue sections, ELISA, RT-PCR, WB, and serum metabolomics.ResultsThe results showed that the optimized extraction conditions for TFZJF included a solid–liquid ratio (SLR) of 1:25 g·mL⁻1, ethanol concentration of 60%, and extraction time of 60 min, yielding an extraction efficiency of 1.98%. Data from the experimental groups indicated dose-dependent sleep improvement in the insomnia model, with the high-dose TFZJF (TFZJF-H) group exhibiting the most significant effect, followed by the medium-dose (TFZJF-M) and low-dose (TFZJF-L) groups. Metabolomic analysis revealed that TFZJF administration positively impacted the metabolic profile of PCPA-induced insomnia, particularly affecting pathways related to phenylalanine, tyrosine, cytochrome P450, and alanine metabolism on non-targeted metabolomics.ConclusionsThe extraction process is stable and reliable, which can be used for the extraction of TFZJF; meanwhile, TFZJF demonstrated significant sleep-enhancing effects in the PCPA-induced insomnia mouse model, supporting its potential for resource development and the utilization of non-medicinal parts ofZiziphus jujube.
Ordered release of genomic RNA during icosahedral virus disassembly
Authors: Zhou Yiyang , Routh Andrew L. 
Published: January 2025

AbstractTo release their genomic cargo, many icosahedral viruses undergo a series of ordered conformational changes via distinct disassembly intermediates that allow nucleic acid egress. Previous studies have focused on the rearrangement of the virus capsid protein shell during disassembly. However, it is unclear whether the packaged viral nucleic acids also undergo defined rearrangements or whether specific regions of the viral genome are released in a predetermined order. In this study, we established a Next-Generation Sequencing platform (“PT-ClickSeq”) that does not require RNA extraction or fragmentation and so can natively sequence the nucleic acid exposed during virus particle disassembly without disrupting the capsid protein. We used Flock House virus (FHV) as a model system, which produces two well-defined disassembly intermediates with externalized RNA. With PT-ClickSeq, we found that FHV releases RNA genome in an ordered and conserved fashion with the 5’ and 3’ terminal regions of viral genomic RNAs and specific loci within the viral genome being released first during virus particle disassembly. Further, different genomic loci exhibit distinct energy barriers prior to release, suggesting a programmed exposure of the viral RNA. We also characterized viral RNA-capsid interactions using established cross-linking and NGS approaches (“vPAR-CL”) and observed a disordering of RNA-capsid interactions during disassembly. Interestingly, we noticed an anti-correlation between preferentially released RNA regions and strong RNA-capsid interactions observed prior to disassembly. These findings demonstrate that rather than being a passive cargo, the encapsidated viral genome serves an important role in programmed virus disassembly.SignificanceViruses need to strike a balance between structural rigidity and flexibility, to achieve both sufficient protection and rapid release of packaged genome into host cells. During the process of genome delivery, many viruses undergo a programed disassembly process through successive morphological changes, which give rise to partially dissembled virus particles, termed disassembly intermediates. It is important to study these intermediates as “checkpoints” to understand virus disassembly dynamics. We established a next-generation sequencing method that can monitor the RNA behavior during these conformational changes. We found that different regions of RNA were released with different energy thresholds and the RNA release prioritized regions with low RNA-protein interactions. These findings shed light on the active role of the viral RNA in virus disassembly.
Production of single doubly charged Higgs bosons at muon colliders
Authors: Jia Jie-Cheng , Han Zhi-Long , Huang Fei , Jin Yi , Li Honglei 
Published: January 2025

In this paper, we study the single production of doubly charged Higgs H±± in the type-II seesaw at the high energy muon collider. Compared with the pair production channel μ+μ−→H++H−−, the single production channel μ+μ−→μ∓ℓ∓H±± in principle could probe the mass region above the threshold mH±±>s/2. The single production channel depends on the Yukawa coupling h, which is related to the neutrino oscillation parameters. We show that the Majorana phases ϕ1 and ϕ2 have great impact on the individual cross section of the single production. We find that the same sign dilepton signature from H±±→ℓ±ℓ± could probe mH±±≲2.6(7.1)  TeV at the 3 (10) TeV muon collider when the triplet VEV vΔ≲3  eV.

Published by the American Physical Society
2025
The impact of keyword characteristics on seller performance in e-commerce platforms: focusing on the moderating effect of product types
Authors: Lee Jungwon , Yu Jun , You Jae Hyun 
Published: January 2025

PurposeDrawing on the shopping goal theory, this study sets the following research questions. Research question 1: How do keyword characteristics of e-commerce platforms affect seller performance? Research question 2: Do these effects differ according to product type (utilitarian vs hedonic)?Design/methodology/approachEmpirical analysis was conducted using a dataset of 24,907 keywords collected from 30 product categories on Amazon. Multi-level modeling was used to distinguish between product level and keyword level.FindingsRegression analysis showed that keyword readability, customer characteristic keywords and brand characteristic keywords positively affect seller sales. The influence of these keyword characteristics on seller performance varied significantly across different product types.Originality/valueThe exploratory results of this study expanded existing studies by adding keyword characteristics to the factors that determine e-commerce platform seller performance and expanded the literature that mainly examines search engine keyword characteristics. In addition, by newly utilizing the LIWC (Linguistic Inquiry and Word Count) methodology, this study provided a novel contribution to the literature on keyword characteristics.
The concept of Finnish civil defence shelters
Authors: Koivukoski Janne 
Published: January 2025

PurposeThe aim of this study was to describe the development of Finnish civil defence shelter construction from the 1920s to the present. The purpose of the article is primarily to share information about the birth and development history of the Finnish civil defence system.Design/methodology/approachThe study is a literary study, including the stages of legislative preparation. The research data is analysed using path dependency theory. The study uses path dependency theory to analyse the development of civil defence shelter construction.FindingsThe paper provides empirical picture about how the development of construction of civil defence shelters was started by voluntary basis and then development was stipulated by legislation. Path dependency can be used to explain how previous investments in infrastructure or technology have affected decision-making. The technical system of shelters was preserved in terms of conventional pressure protection and developed through changes in the socio-economic system as well as by the threat of nuclear war.Research limitations/implicationsThe study describes solely development of Finnish civil defence shelter concept. There is a need for a separate international comparative study of developments in different countries and international strategies for civil defence.Practical implicationsThe paper reviews the step-by-step development of Finnish civil defence shelters over time, including legislation and technical standards, highlighting the importance of civil defence shelters.Originality/valueSeveral Finnish-language studies have been published on the historical development of the construction of Finnish civil defence shelters, but the internationally published unified historical review has not previously been published. This study provides Finnish model and example for the development of civil defence.
An analysis of Guskey’s framework of teachers’ perceptions and experiences in integrating ICTs for lesson study
Authors: Govender Nadaraj , Juggernath Avashkumar 
Published: January 2025

PurposeThis study explored high school teachers’ perceptions and collaborative learning experiences in integrating information and communication technologies (ICTs) in teaching using lesson study (LS) whilst engaging in teacher professional development (TPD). Earlier forms of TPD were often theoretical, and teachers had difficulty in applying ICT knowledge and skills for classroom applications. A comprehensive Guskeys’ framework was used to determine whether it was a suitable model for analysing teachers’ perceptions and experiences in integrating ICTs for LS.Design/methodology/approachTeachers were exposed to an LS intervention over seven months. About 12 teachers participated in an LS programme. An action-research approach was followed in two cycles with three workshops. During each phase in the cycle, teachers reflected on their lessons in subject groups and on how ICTs were to be integrated into their classrooms. A qualitative approach, case-study embedded in the interpretivist paradigm, was selected. The data were collected using documents in the form of written reflections and interviews. Data were coded, categorized and developed into themes. The analysis was conducted using a comprehensive Guskey’s five hierarchical levels.FindingsGuskey’s comprehensive framework indicated from teachers’ perceptions and experiences, during an LS intervention, that they gained practical knowledge and skills in the use of ICT resources whilst planning lessons for classroom teaching. They also acquired collaborative skills during LS. However, they reported challenges like finding time for LS commitments, a high teaching workload and students’ unfamiliarity with the use of ICTs.Research limitations/implicationsThe study was conducted as a Ph.D. project and hence was limited as students’ learning outcomes could not be explored deeply. Also, the sample selection was limited to only teachers who were engaging in some ICT practices.Practical implicationsGuskey’s 5 framework is useful for LS. The comprehensive Guskey’s framework analysis provides key concepts pinpointing teachers’ valuable experiences in integrating ICT for LS. It is recommended that teachers and school management should consider these valuable concepts in developing an LS programme especially for ICT enhancement.Social implicationsThe study has social implications in that teachers can collaborate effectively to plan and present lessons in a LS programme guided by the comprehensive Guskey’s framework.Originality/valueThe study contributes towards an analysis of the usefulness of Guskey’s framework of five hierarchical levels with detailed themes in analysing teachers’ perceptions, collaborative experiences and reflections of integrating ICT into lesson plans for classroom teaching. The study concludes that the comprehensive Guskey’s framework does provide a useful structure for LS intervention in TPD.
How do talent and technology factors affect supply chain robustness and resilience? Evidence from Chinese manufacturers
Authors: Zheng Liqiao , Song Guang , Song Shaohua , Huang Ning , Cheng T.C.E. 
Published: January 2025

PurposeIn the face of frequent supply chain disruptions, this study aims to identify the relationships between human capital (HC), digital supply chain practice (DSCP) and supply chain robustness and resilience (i.e. SCRO and SCRE).Design/methodology/approachTo examine the proposed conceptual model based on the resource-based view and organizational information processing theory, an empirical study was conducted using a sample of Chinese manufacturers. Hierarchical regression is applied to understand the direct effect, mediating effect and moderating effect among HC, DSCP, SCRO, SCRE and digital culture.FindingsThe results reveal that HC positively influences digital maturity and supply chain resilience. DSCP positively affects both SCRO and SCRE. However, HC does not significantly influence the adoption of digital tools, and only employees’ capital has a positive relationship with SCRO. In addition, the moderating effect of digital culture on the relationship between HC and DSCP was examined.Originality/valueAs an early exploration of the relationships among HC, DSCP, SCRO and SCRE, this study enriches the literature by offering new insights and responding to the call for more empirical research and theoretical application. It emphasizes the importance of HC and DSCP as strategic resources and highlights the need for a digital culture to implement DSCP.
A Delphi study on digital maturity and digital competitiveness in the context of digital transformation
Authors: Touijer Mohamed Noureddine , Elabjani Abdelaziz 
Published: January 2025

Purpose
The purpose of this study is to conceptualize and propose a framework for examining digital maturity (DM) and digital competitiveness (DC) in small and medium-sized enterprises (SMEs). It aims to provide an understanding on how DM can enhance organizational performance, innovation and sustainable growth in the context of DC and strategic change.

Design/methodology/approach
The Delphi method is used in this study to gather insights from 37 experts in digital transformation and change management in Morocco. Using a structured questionnaire and IRaMuTeQ software, the study analyzes responses to identify key themes related to DM and DC in SMEs, providing a comprehensive analytical framework.

Findings
The research highlighted the importance of a comprehensive framework that includes strategy, leadership, information and communication technology infrastructure and customer orientation to assess DM. The study found that SMEs face significant barriers such as digital skills shortages, financial constraints and infrastructural deficits. Despite these challenges, there is a strong recognition of the role of digital technologies in enhancing internal processes and strategic competitiveness. The study calls for customer-focused digital strategies and dematerialized processes to achieve operational efficiency and sustainability.

Practical implications
This study provides SMEs with practical steps to improve their DM. SMEs should focus on simplifying their internal processes by moving away from paper-based systems, adopting tools like cloud services and artificial intelligence (AI) to boost efficiency and developing customer-focused strategies to offer better value. Policymakers should support these businesses by offering financial aid for digital tools, creating programs to improve digital skills and building a stronger digital infrastructure. By doing so, SMEs can become more adaptable, efficient and competitive in today’s digital world.

Originality/value
This study stands out due to its localized focus on Moroccan SMEs, offering insights into DM in a context that has received little attention. By using the Delphi method, it draws on the perspectives of experts in DT to provide a deep understanding of the challenges faced by SMEs. The study also uses IRaMuTeQ software to analyze expert feedback, combining both qualitative and quantitative insights. This approach helps build a new framework linking DM with competitiveness, offering valuable contributions to both theory and practical application for improving DT in SMEs.
Digital transformation in SMEs: global maps and trends of research
Authors: Elsa Dina , Indrawati Henny , Caska Caska 
Published: January 2025

Purpose
This paper reviews the literature on digital transformation in SMEs. The general purpose of the paper is to provide an overview of the evolution of digital transformation research in SMEs globally and propose possible future research directions to advance digital transformation research in SMEs.

Design/methodology/approach
This study used a systematic review of the literature by conducting bibliometric analysis and content analysis. The research protocol included 51 articles collected in the Scopus database in the bibliometric analysis. The Scopus database was searched using Publish or Perish, while Excel and Mendeley assistance were used for quantitative investigation of the sample and bibliographic management. A bibliometric analysis was conducted by combining two software applications, Biblioshiny R Studio and VOSviewer.

Findings
Digital transformation (DT) research on SMEs has increased significantly especially after 2015. Using bibliometric analysis and science mapping, seven main research themes were found, namely digital technologies, dynamic capability, digitalization, small and medium enterprises, big data, manufacturing sector and innovation. Seven future DT research trends were also found, namely digital technology adoption, dynamic capability, adaptive leadership, digital literacy, sustainable innovation, managerial readiness and external support.

Originality/value
Compared to existing reviews, we adopt a broader approach and one that does not focus on specific aspects of DT, but adopts an integrated and holistic approach that provides a comprehensive overview of the DT literature in SMEs. In addition to quantitative analysis through bibliometrics, this study also integrated content analysis to determine future research opportunities and directions.

Research limitations
This paper is based on imported bibliographic data from Scopus. The findings of bibliometric analysis may be affected by the use of certain databases. Therefore, the results depend on the selected databases which may lead to different results. Although the literature review procedure was applied, it is possible that there were missed articles related to the topic discussed. The use of different indicators and depiction methods will also lead to different results. Therefore, future researchers should optimize these aspects.
How the environmental friendliness of food delivery packages shapes sustainable customer behavior
Authors: Ting Liu , Ahn Jiseon 
Published: January 2025

Purpose
Due to increasing interest in sustainability, consumers prioritize environmentally friendly consumption across various service sectors. This study aims to examine how environment-related attributes of food delivery services affect customer behavior. Specifically, the authors use the stimulus-organism-response framework to explore how environmentally friendly food packages correlate with customers’ environmental support and patronage behavior.

Design/methodology/approach
The authors collected data from US food delivery service customers. To test the hypotheses, the authors used partial least squares structural equation modeling.

Findings
The authors find that customers’ perceptions of the environmental friendliness of food packages influence their satisfaction and trust, which in turn affect their environmental support and patronage behaviors. Also, customers’ trust and satisfaction mediate the relationship between their food consumption experience and its outcomes. The authors further explore demographic factors that influence the proposed relationships.

Originality/value
Due to the popularity of food delivery services, this study has theoretical and practical implications for restaurant service providers and highlights the potential of environmentally friendly packaging to increase both environmental support and loyal behavior.
Hydrocarbon reservoir definition and delineation using log analysis, petrophysics and rock physics in Y-Field, offshore Nigerian Niger Delta
Authors: Ibrahim Abdulbariu , Raji Wasiu O. 
Published: January 2025

Purpose
This study aims to characterize the reservoirs through well log analysis, intensive elastic log studies and cross-plotting (rock physics studies) of the Y-Field reservoirs to define the reservoirs hosting hydrocarbons in the basin with structural complexity. Poor evaluation of sand body has been part of the problem leading to wet wells and these above methods accounted for this gap.

Design/methodology/approach
The basic parameters needed for the characterization are P-wave (Vp), S-wave (Vs) and density (ρ) and understanding the relationship between these parameters with the pore-fluid and lithology is of utmost importance in the evaluation of sand body. This was achieved through elastic rock physics studies. Important among these elastic logs include P-impedance (Zp), S-impedance (Zs), Vp/Vs ratio, Poisson’s ratio, lambda-rho (λρ) and mu-rho (µρ), and are critical. Rock physics diagnosis involving elastic log generation and analysis accompanied by cross-plotting of the elastic logs color-coded with petrophysical properties were employed.

Findings
The findings from the elastic logs indicated that hydrocarbon-charged units are characterized by low Zp, Zs, Vp/Vs ratio, Poisson’s ratio, λρ and µρ resulting from a significant drop in P-wave and density because of hydrocarbon presence. The results also showed that some of the reservoirs with hydrocarbon accumulations exhibit high Vp/Vs and Poisson’s ratio as against their usual low values in hydrocarbon intervals which results from the presence of shale with high plasticity. The elastic logs cross-plots of Vp/Vs with Zp, Poisson’s ratio with Zp and λρ with µρ successfully distinguished between the hydrocarbon-charged zone and the brine-saturated units. All these outcomes are the benefits of this research.

Originality/value
It can be shown that the analysis/results have distinguished hydrocarbon-charged units from brine-saturated intervals and the originality lies in the integration of various sophisticated fluid identification templates.