bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thin-film PMUTs: a review of over 40 years of research
Authors: Roy Kaustav , Lee Joshua En-Yuan , Lee Chengkuo 
Published: July 2023

AbstractThin-film PMUTs have been important research topics among microultrasound experts, and a concise review on their research progress is reported herein. Through rigorous surveying, scrutinization, and perception, it has been determined that the work in this field began nearly 44 years ago with the primitive development of functional piezoelectric thin-film materials. To date, there are three major companies commercializing thin-film PMUTs on a bulk scale. This commercialization illustrates the extensive contributions made by more than 70 different centers, research institutes, and agencies across 4 different continents regarding the vast development of these devices’ design, manufacturing, and function. This review covers these important contributions in a short yet comprehensive manner; in particular, this paper educates readers about the global PMUT outlook, their governing design principles, their manufacturing methods, nonconventional yet useful PMUT designs, and category-wise applications. Crucial comparison charts of thin-film piezoelectric material used in PMUTs, and their categorically targeted applications are depicted and discussed to enlighten any MEMS designer who plans to work with PMUTs. Moreover, each relevant section features clear future predictions based on the author’s past knowledge and expertise in this field of research and on the findings of a careful literature survey. In short, this review is a one-stop time-efficient guide for anyone interested in learning about these small devices.
Deconvolution volumetric additive manufacturing
Authors: Orth Antony , Webber Daniel , Zhang Yujie , Sampson Kathleen L. , de Haan Hendrick W. , Lacelle Thomas , Lam Rene , Solis Daphene , Dayanandan Shyamaleeswari , Waddell Taylor , Lewis Tasha , Taylor Hayden K. , Boisvert Jonathan , Paquet Chantal 
Published: July 2023

AbstractVolumetric additive manufacturing techniques are a promising pathway to ultra-rapid light-based 3D fabrication. Their widespread adoption, however, demands significant improvement in print fidelity. Currently, volumetric additive manufacturing prints suffer from systematic undercuring of fine features, making it impossible to print objects containing a wide range of feature sizes, precluding effective adoption in many applications. Here, we uncover the reason for this limitation: light dose spread in the resin due to chemical diffusion and optical blurring, which becomes significant for features ⪅0.5 mm. We develop a model that quantitatively predicts the variation of print time with feature size and demonstrate a deconvolution method to correct for this error. This enables prints previously beyond the capabilities of volumetric additive manufacturing, such as a complex gyroid structure with variable thickness and a fine-toothed gear. These results position volumetric additive manufacturing as a mature 3D printing method, all but eliminating the gap to industry-standard print fidelity.
Atomically precise nanoclusters predominantly seed gold nanoparticle syntheses
Authors: Qiao Liang , Pollard Nia , Senanayake Ravithree D. , Yang Zhi , Kim Minjung , Ali Arzeena S. , Hoang Minh Tam , Yao Nan , Han Yimo , Hernandez Rigoberto , Clayborne Andre Z. , Jones Matthew R. 
Published: July 2023

AbstractSeed-mediated synthesis strategies, in which small gold nanoparticle precursors are added to a growth solution to initiate heterogeneous nucleation, are among the most prevalent, simple, and productive methodologies for generating well-defined colloidal anisotropic nanostructures. However, the size, structure, and chemical properties of the seeds remain poorly understood, which partially explains the lack of mechanistic understanding of many particle growth reactions. Here, we identify the majority component in the seed solution as an atomically precise gold nanocluster, consisting of a 32-atom Au core with 8 halide ligands and 12 neutral ligands constituting a bound ion pair between a halide and the cationic surfactant: Au32X8[AQA+•X-]12 (X = Cl, Br; AQA = alkyl quaternary ammonium). Ligand exchange is dynamic and versatile, occurring on the order of minutes and allowing for the formation of 48 distinct Au32 clusters with AQAX (alkyl quaternary ammonium halide) ligands. Anisotropic nanoparticle syntheses seeded with solutions enriched in Au32X8[AQA+•X-]12 show narrower size distributions and fewer impurity particle shapes, indicating the importance of this cluster as a precursor to the growth of well-defined nanostructures.
Genetic variation in the immunoglobulin heavy chain locus shapes the human antibody repertoire
Authors: Rodriguez Oscar L. , Safonova Yana , Silver Catherine A. , Shields Kaitlyn , Gibson William S. , Kos Justin T. , Tieri David , Ke Hanzhong , Jackson Katherine J. L. , Boyd Scott D. , Smith Melissa L. , Marasco Wayne A. , Watson Corey T. 
Published: July 2023

AbstractVariation in the antibody response has been linked to differential outcomes in disease, and suboptimal vaccine and therapeutic responsiveness, the determinants of which have not been fully elucidated. Countering models that presume antibodies are generated largely by stochastic processes, we demonstrate that polymorphisms within the immunoglobulin heavy chain locus (IGH) impact the naive and antigen-experienced antibody repertoire, indicating that genetics predisposes individuals to mount qualitatively and quantitatively different antibody responses. We pair recently developed long-read genomic sequencing methods with antibody repertoire profiling to comprehensively resolve IGH genetic variation, including novel structural variants, single nucleotide variants, and genes and alleles. We show that IGH germline variants determine the presence and frequency of antibody genes in the expressed repertoire, including those enriched in functional elements linked to V(D)J recombination, and overlapping disease-associated variants. These results illuminate the power of leveraging IGH genetics to better understand the regulation, function, and dynamics of the antibody response in disease.
Description of lipase producing novel yeast species Debaryomyces apis f.a., sp. nov. and a modified pH indicator dye-based method for the screening of lipase producing microorganisms
Authors: Kumari Alka , Mihooliya Kanti N. , Sahoo Debendra K. , Bhattacharyya Mani S. , Prasad Gandham S. , Pinnaka Anil Kumar 
Published: July 2023

AbstractFour yeast strains were isolated from the gut of stingless bee, collected in Churdhar, Himachal Pradesh, India. Physiological characterization, morphological examination, and sequence analysis of small subunit ribosomal RNA (18S rRNA) genes, internal transcribed spacer (ITS) region, and D1/D2 domain of the large subunit rRNA gene revealed that the four strains isolated from the gut of stingless bee belonged to the Debaryomyces clade. Strain CIG-23HT showed sequence divergence of 7.5% from Debaryomyces nepalensis JCM 2095T, 7.8% from Debaryomyces udenii JCM 7855T, and Debaryomyces coudertii JCM 2387T in the D1/D2 domain. In the ITS region sequences, strain CIG-23HT showed a 15% sequence divergence from Debaryomyces nepalensis JCM 2095T and Debaryomyces coudertii JCM 2387T. In 18S rRNA gene sequence, the strain CIG-23HT showed 1.14% sequence divergence from Debaryomyces nepalensis JCM 2095 and and Debaryomyces coudertii JCM 2387, and 0.83% sequence divergence from Debaryomyces hansenii NRRL Y-7426. Strain CIG-23HT can utilize more carbon sources than closely related species. The findings suggest that strain CIG-23HT is a novel species of the genus Debaryomyces, and we propose to name it as Debaryomyces apis f.a., sp. nov. The holotype is CBS 16297T, and the isotypes are MTCC 12914T and KCTC 37024T. The MycoBank number of Debaryomyces apis f.a., sp. nov. is MB836065. Additionally, a method using cresol red and Bromothymol blue pH indicator dyes was developed to screen for lipase producers, which is more sensitive and efficient than the currently used phenol red and rhodamine B dye-based screening methods, and avoids the problem of less differentiable zone of hydrolysis.
Anaesthesia by intravenous propofol reduces the incidence of intra-operative gastric electrical slow-wave dysrhythmias compared to isoflurane
Authors: Aghababaie Zahra , Wang Tim Hsu-Han , Nisbet Linley A. , Matthee Ashton , Dowrick Jarrah , Sands Gregory B. , Paskaranandavadivel Niranchan , Cheng Leo K. , O’Grady Gregory , Angeli-Gordon Timothy R. 
Published: July 2023

AbstractGastric motility is coordinated by bioelectrical slow-wave activity, and abnormal electrical dysrhythmias have been associated with nausea and vomiting. Studies have often been conducted under general anaesthesia, while the impact of general anaesthesia on slow-wave activity has not been studied. Clinical studies have shown that propofol anaesthesia reduces postoperative nausea and vomiting (PONV) compared with isoflurane, while the underlying mechanisms remain unclear. In this study, we investigated the effects of two anaesthetic drugs, intravenous (IV) propofol and volatile isoflurane, on slow-wave activity. In vivo experiments were performed in female weaner pigs (n = 24). Zolazepam and tiletamine were used to induce general anaesthesia, which was maintained using either IV propofol (n = 12) or isoflurane (n = 12). High-resolution electrical mapping of slow-wave activity was performed. Slow-wave dysrhythmias occurred less often in the propofol group, both in the duration of the recorded period that was dysrhythmic (propofol 14 ± 26%, isoflurane 43 ± 39%, P = 0.043 (Mann–Whitney U test)), and in a case-by-case basis (propofol 3/12, isoflurane 8/12, P = 0.015 (Chi-squared test)). Slow-wave amplitude was similar, while velocity and frequency were higher in the propofol group than the isoflurane group (P < 0.001 (Student’s t-test)). This study presents a potential physiological biomarker linked to recent observations of reduced PONV with IV propofol. The results suggest that propofol is a more suitable anaesthetic for studying slow-wave patterns in vivo.
An exploratory study on the association between serotonin and sleep breathing disorders
Authors: Wieckiewicz Mieszko , Martynowicz Helena , Lavigne Gilles , Lobbezoo Frank , Kato Takafumi , Winocur Efraim , Wezgowiec Joanna , Danel Dariusz , Wojakowska Anna , Mazur Grzegorz , Smardz Joanna 
Published: July 2023

AbstractThis exploratory observational study aimed to evaluate whether the blood levels of serotonin and enzymes involved in serotonin synthesis are associated with sleep breathing parameters. A total of 105 patients were included in this study, who were subjected to single-night polysomnography with simultaneous audio–video recordings. Peripheral blood samples were collected to estimate the serum levels of serotonin, tryptophan hydroxylase 1 (TPH1), and aromatic l-amino acid decarboxylase (AADC). Results showed a negative correlation between blood serotonin levels, and oxygen desaturation index (ODI) (p = 0.027), central apnea (p = 0.044) and obstructive apnea (OA) (p = 0.032) scores. Blood TPH1 levels were negatively correlated with average (p = 0.003) and minimal saturation (p = 0.035) and positively correlated with apnea–hypopnea index (p = 0.010), OA (p = 0.049), and hypopnea index (p = 0.007) scores. A tendency to sleep-disordered breathing seemed to co-occur with lower blood serotonin and higher TPH1 levels.Clinical Trial Registration :www.ClinicalTrials.gov, identifier NCT04214561
Free viewing biases for complex scenes in preschoolers and adults
Authors: Linka Marcel , Sensoy Özlem , Karimpur Harun , Schwarzer Gudrun , de Haas Benjamin 
Published: July 2023

AbstractAdult gaze behaviour towards naturalistic scenes is highly biased towards semantic object classes. Little is known about the ontological development of these biases, nor about group-level differences in gaze behaviour between adults and preschoolers. Here, we let preschoolers (n = 34, age 5 years) and adults (n = 42, age 18–59 years) freely view 40 complex scenes containing objects with different semantic attributes to compare their fixation behaviour. Results show that preschool children allocate a significantly smaller proportion of dwell time and first fixations on Text and instead fixate Faces, Touched objects, Hands and Bodies more. A predictive model of object fixations controlling for a range of potential confounds suggests that most of these differences can be explained by drastically reduced text salience in pre-schoolers and that this effect is independent of low-level salience. These findings are in line with a developmental attentional antagonism between text and body parts (touched objects and hands in particular), which resonates with recent findings regarding ‘cortical recycling’. We discuss this and other potential mechanisms driving salience differences between children and adults.
Critical assessment of emissions, costs, and time for last-mile goods delivery by drones versus trucks
Authors: Raghunatha Aishwarya , Lindkvist Emma , Thollander Patrik , Hansson Erika , Jonsson Greta 
Published: July 2023

AbstractElectric drones as an autonomous mode of transport are scaling up to transform last-mile goods delivery, raising an urgent need for assessing impacts of drone transport from a systems perspective. In this paper, we conduct systems analyses to assess the environmental, economic, and delivery time impact of large drones for delivery scenarios to pick-up centers between mid-size cities predominantly in rural areas, and deliveries within city limits compared with electric and diesel trucks. Results show that large drones have lower emissions than diesel trucks for deliveries in rural areas and that drones don’t compete with electric trucks, mainly due to the high energy demand required for take-off and landing for each delivery. Furthermore, we show that electric drones are an economically more cost-effective option than road-bound transport modes such as diesel and electric trucks due to the high degree of automation, and also provide the fastest delivery times. Our analysis provides unique insights that drones can address rapid electrification and emergency applications due to low costs, high flexibility, and fast operations. However, for regulators and practitioners to realize it as an emission-friendly option it is necessary to determine the optimal size of drones, particularly for use cases in urban areas, avoid very low landings for deliveries, and have home deliveries instead of pick-up points.
The soft rock can promote the improvement of aeolian sandy soil in Mu Us Sandy Land, China
Authors: Guo Zhen , Li Juan , Zhang Yang , Wang Huanyuan , Li Wanying 
Published: July 2023

AbstractThis study focuses on the significance of improving the land degradation of Mu Us Sandy Land to increase cultivated land area and promote ecological green development. The research objects were four kinds of mixed soils, and rhizosphere soils were collected during the crop harvesting period. The volume ratio of soft rock to sand was 0:1 (control check, CK), 1:5 (composite soil one, PS1), 1:2 (composite soil two, PS2), and 1:1 (composite soil three, PS3). The results showed that the large aggregates were primarily mechanically stable aggregates, while the small aggregates were mainly water-stable aggregates. The soft rock promoted the increase of clay and silt content in sandy soil, and the soil texture changed from sand to loam. The contents of organic matter, available phosphorus, and available potassium increased significantly under PS2 and PS3 treatments, but there was no significant difference between them. Total nitrogen had no significant difference among treatments. Actinobaciota, Proteobateria, and Chloroflexi were the dominant bacteria in rhizosphere soil, accounting for about 75% of all microorganisms. At the Genus level, the soft rock contributes to richer species composition. The diversity index, evenness index, and richness index was higher in PS1, and the available phosphorus and available potassium content promoted the increase of diversity. Therefore, when the proportion of soft rock and sand compound soil is between 1: 5 and 1: 2, it can be used as an important basis and technical parameter for Mu Us Sandy Land improvement.
Association between CYP2B6 genetic variability and cyclophosphamide therapy in pediatric patients with neuroblastoma
Authors: Mangó Katalin , Fekete Ferenc , Kiss Ádám Ferenc , Erdős Réka , Fekete János Tibor , Bűdi Tamás , Bruckner Edit , Garami Miklós , Micsik Tamás , Monostory Katalin 
Published: July 2023

AbstractCyclophosphamide, an oxazaphosphorine prodrug is frequently used in treatment of neuroblastoma, which is one of the most prevalent solid organ malignancies in infants and young children. Cytochrome P450 2B6 (CYP2B6) is the major catalyst and CYP2C19 is the minor enzyme in bioactivation and inactivation pathways of cyclophosphamide. CYP-mediated metabolism may contribute to the variable pharmacokinetics of cyclophosphamide and its toxic byproducts leading to insufficient response to the therapy and development of clinically significant side effects. The aim of the study was to reveal the contribution of pharmacogenetic variability in CYP2B6 and CYP2C19 to the treatment efficacy and cyclophosphamide-induced side effects in pediatric neuroblastoma patients under cyclophosphamide therapy (N = 50). Cyclophosphamide-induced hematologic toxicities were pivotal in all patients, whereas only moderate hepatorenal toxicity was developed. The patients’ CYP2B6 metabolizer phenotypes were associated with the occurrence of lymphopenia, thrombocytopenia, and monocytopenia as well as of liver injury, but not with kidney or urinary bladder (hemorrhagic cystitis) toxicities. Furthermore, the patients’ age (< 1.5 years, P = 0.03) and female gender (P ≤ 0.02), but not CYP2B6 or CYP2C19 metabolizer phenotypes appeared as significant prognostic factors in treatment outcomes. Our results may contribute to a better understanding of the impact of CYP2B6 variability on cyclophosphamide-induced side effects.
Rapid and accurate taxonomic classification of cpn60 amplicon sequence variants
Authors: Ren Qingyi , Hill Janet E 
Published: July 2023

Abstract
The “universal target” region of the gene encoding the 60 kDa chaperonin protein (cpn60, also known as groEL or hsp60) is a proven sequence barcode for bacteria and a useful target for marker gene amplicon-based studies of complex microbial communities. To date, identification of cpn60 sequence variants from microbiome studies has been accomplished by alignment of queries to a reference database. Naïve Bayesian classifiers offer an alternative identification method that provides variable rank classification and shorter analysis times. We curated a set of cpn60 barcode sequences to train the RDP classifier and tested its performance on data from previous human microbiome studies. Results showed that sequences accounting for 79%, 86% and 92% of the observations (read counts) in saliva, vagina and infant stool microbiome data sets were classified to the species rank. We also trained the QIIME 2 q2-feature-classifier on cpn60 sequence data and demonstrated that it gives results consistent with the standalone RDP classifier. Successful implementation of a naïve Bayesian classifier for cpn60 sequences will facilitate future microbiome studies and open opportunities to integrate cpn60 amplicon sequence identification into existing analysis pipelines.
Military spending crowding out health and education spending: which views are valid in Egypt?
Authors: Elish Eman , Ahmed Hossam Eldien , AboElsoud Mostafa E. 
Published: July 2023

AbstractThis study examines the relationship between government spending, specifically military spending, government spending on health, government spending on education, and economic growth in Egypt over the period from 1980 to 2021. The paper utilizes a Granger causality test to detect the directional relationship between spending components and GDP growth. Furthermore, an autoregressive distributed lag (ARDL) model, including error-correction models, was established to determine the long- and short-term relationships among these variables. The study contrasts Wagner’s versus Keynes’s views of the government spending relationship with economic growth, with a greater emphasis on Keynes’s argument for military spending enhancing economic growth. While previous studies have investigated the relationship between aggregate spending and economic growth from a single or two-way direction of causality, the present study contributes to the literature by exploring the possibility of military spending crowding out spending on health and education and detecting this causality and dynamic relationship. The empirical results support the Keynesian view of causality from all government spending components to economic growth. However, short- and long-term analyses revealed a negative relationship between military spending and economic growth. Moreover, the short-term impact of government spending on education and health on economic growth is negative, but positive in the long-term. Finally, the causality test revealed that military spending influences health and education spending. Additionally, a unidirectional relationship exists between military spending and health expenditure, which requires further research. The policy implication of this study shows that although spending is exogenous to economic growth, it does not align with the Keynesian view of inducing growth. Instead, spending has negative current and future implications for economic development.
Determining factors and alternatives for the career development of women executives: a multicriteria decision model
Authors: Martín-Peña María Luz , Cachón-García Cristina R. , De Vicente y Oliva María A. 
Published: July 2023

AbstractDespite advances in women’s access to managerial positions, the glass ceiling still restricts women’s participation in corporate decision-making. Theoretical studies have examined the determining factors and career alternatives for women’s professional development to understand the roots of this problem. However, analysis aimed at establishing the causal relationships and exploring the implications of this phenomenon is missing from the literature. To fill this gap, this paper provides an overview of the determinants of the career development of women executives and explores how these factors influence their alternatives for professional development. A sample of Spanish women executives is examined using multicriteria decision techniques, and associations are established between factors and alternatives for women executives’ career development. This paper contributes to the topic of gender in management literature by enhancing the theoretical foundations and empirical validation surrounding the phenomenon of the glass ceiling. It has managerial implications in providing companies with an empirical basis for understanding the orientation of women’s career development.
Addendum for: Solar cell parameter accuracy improvement, via refinement of the Co-Content function. Part 1: theoretical analysis (2022 Eng. Res. Express
4 015022)
Authors: Rangel-Kuoppa Victor Tapio 
Published: July 2023

Abstract
This paper is an addendum to reference Rangel-Kuoppa 2022 Eng. Res. Express 4 015022), in which the application of Co-Content function

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