bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of COVID-19 pandemic on mental burden and quality of life in physicians: Results of an online survey
Authors: Wetzel Lea , Halfmann Marie , Castioni Noah , Kiefer Falk , König Sarah , Schmieder Astrid , Koopmann Anne 
Published: April 2023

BackgroundIn previous pan-/epidemics such as the SARS epidemic of 2002/2003, negative effects on the wellbeing and an increase in symptoms of depression and anxiety were observed in doctors due to social isolation and the threat they experienced. Therefore, it is feared that the COVID-19 pandemic will also have a negative impact on the mental health and quality of life of doctors.ObjectiveThe impact of the COVID-19 pandemic on the mental health of physicians. In particular, on the subjective anxiety and burden, depression and quality of life for the total sample and subsamples (work in COVID-19 units vs. no work in COVID-19 units).Materials and methodsIn an online survey, 107 physicians (23–42 years) were asked about their mental health during the COVID-19 pandemic. In addition to socio-demographic data, pandemic- and work-related data were also included. For example, infection control measures, deployment on COVID-19 wards and the subjective perceived threat posed by the pandemic. The physicians were asked to rate their perceived anxiety and stress, retrospectively, at 7 different points in time during the pandemic. The Hospital Anxiety and Depression Scale (HADS) was used to retrospectively assess symptoms of anxiety and depression before and after the onset of the pandemic. The quality of life of the participants after 2 years of the pandemic was assessed using the WHO Quality of Life (WHOQOL-BREF).ResultsBoth subjective anxiety and burden showed wave-like patterns with higher scores in autumn, winter and spring. We observed significant differences between the seven measurement time points for anxiety [Chi2(6) = 197.05, p &lt; 0.001] as well as for burden [Chi2(6) = 106.33, p &lt; 0.001]. Symptoms of depression and anxiety increased significantly during the COVID-19 pandemic (M = 14.16, SD = 7.83) compared to the pre-pandemic time [M = 7.31, SD = 5.14, t(106) = −10.67, p &lt; 0.001]. Physicians who worked at COVID-19 units showed higher scores in quality of life related to social relationships (M = 70.39, SD = 17.69) than physicians not working at COVID-19 units [M = 61.44, SD = 24.55, t(90.14) = −2.145, p = 0.035]. The multi-factorial ANOVA showed that previous psychiatric illness (p &lt; 0.001), greater difference in depression scores (p = 0.014), higher anxiety scores (p = 0.048) and less work experience (p = 0.032) led to lower quality of life.ConclusionHospitals should offer specific support, such as supervision, to prevent the development of longer-term psychiatric sequelae likely to lead to sick leave and high costs for the healthcare system.Trial registrationThe study has been registered at the German Clinical Trials Registry (DRKS-ID: DRKS00028984).
Application of interpersonal psychotherapy for late-life depression in China: A case report
Authors: Xu Hua , Koszycki Diana 
Published: April 2023

ObjectivesInterpersonal psychotherapy (IPT) is an effective treatment for late-life depression, but little is known about its acceptability and efficacy in Chinese patients. This case report describes the use of IPT in a depressed elderly Chinese man.MethodsThe patient was a 79-year-old widower who lives alone in a large city in China. This was his first contact with a mental health specialist. His wife died one ago, and his only child lives in the United States with her husband and children. Due to the COVID-19 pandemic, his daughter could not visit him, and his usual social interactions decreased, leaving him feeling isolated, lonely, and depressed. He was diagnosed with a major depressive episode and initially prescribed venlafaxine. However, he failed to show an adequate response to medication and the side effects were intolerable. He was switched to a low dose of Duloxetine (60 mg) combined with IPT.ResultsThe patient’s baseline score on the 17-item Hamilton depression rating scale (HAM-D) was 29, suggesting severe levels of depression. He received 12 sessions of IPT. Role transition was the focus of therapy. Although the patient expressed discomfort in therapy, he developed a good rapport with the therapist and was compliant with treatment. Clinical recovery was achieved at the end of acute IPT treatment (HAM-D score = 1).ConclusionResponse to IPT was excellent in this elderly patient, but several points should be noted. First, mental health-related stigma in China can affect treatment engagement. Second, older Chinese are reluctant to speak openly about their personal experiences and feelings. Hence, repeated emphasis on the principles of confidentiality in psychotherapy and forming a strong therapeutic alliance are important. Third, the “empty-nest” household is an emergent phenomenon in China. Helping elderly Chinese navigate changes in traditional Chinese living arrangements and negotiate filial piety with offspring who have moved away are important issues to address in therapy.
The relationship between health belief and sleep quality of Chinese college students: The mediating role of physical activity and moderating effect of mobile phone addiction
Authors: Gao Xinchao , Li Chuang , Han Beining , Xu Peng , Qu Chenxu 
Published: April 2023

BackgroundPoor sleep quality has become a common health problem encountered by college students.MethodsHealth belief scale (HBS), physical activity rating scale (PARS-3), mobile phone addiction tendency scale (MPATS) and Pittsburgh sleep quality index (PSQI) were adopted to analyze the data collected from survey questionnaires, which were filled out by 1,019 college students (including 429 males and 590 females) from five comprehensive colleges and universities from March 2022 to April 2022. The data collected from survey questionnaires were analyzed using SPSS and its macro-program PROCESS.Results(1) Health belief, physical activity, mobile phone addiction and sleep quality are significantly associated with each other (P &lt; 0.01); (2) physical activity plays a mediating role between health belief and sleep quality, and the mediating effects account for 14.77%; (3) mobile phone addiction can significantly moderate the effect size of health belief (β = 0.062, p &lt; 0.05) and physical activity (β = 0.073, P &lt; 0.05) on sleep quality, and significantly moderate the effect size of health belief on physical activity (β = −0.112, p &lt; 0.001).ConclusionThe health belief of college students can significantly improve their sleep quality; college students’ health belief can not only improve their sleep quality directly, but also improve their sleep quality through physical activity; mobile phone addiction can significantly moderate the effect size of health belief on sleep quality, the effect size of health belief on physical activity, and the effect size of physical activity on sleep quality.
A systematic literature review on the utilization of extended operating room hours to reduce surgical backlogs
Authors: Oliveira Mariana , Bélanger Valérie , Ruiz Angel , Santos Daniel 
Published: April 2023

This article is part of the Research Topic ‘Health Systems Recovery in the Context of COVID-19 and Protracted Conflict'IntroductionHospital managers address elective patient surgical backlogs with different strategies: increasing installed capacity, managing demand and improving efficiency. Recently, and particularly since the COVID-19 elective surgery suspension, extended operating room hours has been used to reduce waiting lists by taking advantage of empty operating rooms and existing surgical teams.MethodsTwo research questions are raised: (1) which are the scientific literature's insights related to the use of extended operating room hours to help reduce surgery backlogs? and (2) provided that a hospital decides to extend its operating room opening time, what are the main challenges and the key aspects to consider in the design and implementation of policies to manage extended operating room hours? A systematic review on Web of Science database was conducted to gather existing literature, published from January 2012 to December 2021, regarding strategies to reduce waiting lists using empty operating rooms outside regular working hours.ResultsA total of 12 papers were selected as relevant to address the two research questions. Results were organized according to their main features, namely setting, type of strategy, methodology, and how human resources are handled.DiscussionThe review suggests that extended operating room hours might be problematic if current staff is used and that a careful choice of patients should be made. However, its potential to reduce waiting times and its implications are discussed only superficially. Therefore, we analyze the implications of extending operating room hours from four different perspectives (management, staff, patients, and strategy deployment) and define some recommendations for policy makers and healthcare managers when implementing it in practice.
Factors associated with the incidence and the expenditure of self-medication among middle-aged and older adults in China: A cross-sectional study
Authors: Liu Yuxin , Zheng Zehao , Wang Xiubo , Xia Jiabei , Zhu Xingce , Cheng Fanjun , Liu Zhiyong 
Published: April 2023

BackgroundWith the accelerated ageing of population and the growing prevalence of various chronic diseases in China, self-medication plays an increasingly important role in complementing the health care system due to its convenience and economy.ObjectiveThis study aimed to investigate the incidence of self-medication and the amount of self-medication expenditure among middle-aged and older adults in China, and to explore factors associated with them.MethodsA total of 10,841 respondents aged 45 years and older from the China Health and Retirement Longitudinal Study (CHARLS) wave 4 which conducted in 2018 were included as the sample of this study. The two-part model was adopted to identify the association between the incidence of self-medication and the amount of self-medication expenditure and specific factors, respectively.ResultsThe incidence of self-medication among Chinese middle-aged and older adults was 62.30%, and the average total and out-of-pocket (OOP) pharmaceutical expenditure of self-medication of the self-medicated individuals were 290.50 and 264.38 Chinese yuan (CNY) respectively. Participants who took traditional Chinese medicine (TCM), self-reported fair, and poor health status, suffered from one and multiple chronic diseases had strongly higher incidence of self-medication. Older age and multiple chronic diseases were strongly associated with higher expenditure of self-medication. Those who took TCM had more self-medication expenditure, while those who drank alcohol had less.ConclusionOur study demonstrated the great prevalence of self-medication among middle-aged and older adults in China and the large pharmaceutical expenditure that come with it, especially in the high-risk groups of self-medication identified in this paper. These findings enhanced our understanding of self-medication behaviors among Chinese middle-aged and older adults and may contribute to the formulation of targeted public health policy.
The health of rural Black communities during COVID: Some affirmations, some surprises
Authors: Newman Sharlene D. , Moss Kimberly , Pichon Melonie , Scott Deborah , Rogers Kileema , Orr Angela , Bui Chuong , Payne-Foster Pamela 
Published: April 2023

Background and objectiveThere are overwhelming health disparities in the Deep South. It is important to include the voice of communities affected by these disparities when developing interventions. The goal of the current study was to develop an academic community engaged partnership to strengthen the ability to address priority health concerns of rural African American communities with a focus on health literacy and health advocacy.MethodsA community-based participatory research approach was used to administer a 15-item community health survey in five rural communities led by African American mayors in Alabama (N = 752). The survey assessed the health concerns and the potential behaviors that may be associated with those health concerns.ResultsThe five communities demonstrated similarities as well as differences in both the health concerns endorsed and the potential health behaviors that may contribute to those concerns. All five communities identified cardiovascular disease as a health concern with three endorsing mental health issues and 2 dental health. With respect to behaviors, all five communities identified either unhealthy eating/exercise and substance use as concerns with one community identifying racism as a risky behavior affecting health.ConclusionThe results presented replicate CBPR studies demonstrating that communities are important sources of information about local health priorities and concerns.
Physiological and Oxidative Responses of Japanese Mint Grown Under Limited Water and Nitrogen Supplies in an Evaporated Greenhouse System
Authors: Sommano Sarana Rose , Kanthawang Naruemon , Janpen Chananchida , Norkum ai Pasin , Wongkaew Malaiporn , Inkham Chaiartid , Van Doan Hien , Cheewangkoon Ratchadawan 
Published: April 2023

Graphical AbstractSchematic diagram of physiological and biochemical responses of Japanese mint grown under the limit supplies of water and nitrogen fertilizer.
Fully resorbable poly-4-hydroxybutyrate (P4HB) mesh for soft tissue repair and reconstruction: A scoping review
Authors: Deeken Corey R. , Chen David C. , Lopez-Cano Manuel , Martin David P. , Badhwar Amit 
Published: April 2023

BackgroundPoly-4-hydroxybutyrate (P4HB) is a fully resorbable, biologically-produced polymer with a strength and flexibility comparable to permanent synthetic polymers. The objective was to identify/summarize all peer-reviewed publications involving P4HB mesh.MethodsA scoping review was conducted within PubMed and included articles published through October 2022.ResultsA total of n = 79 studies were identified (n = 12 in vitro/bench; n = 14 preclinical; n = 6 commentaries; n = 50 clinical). Of the clinical studies, n = 40 reported results applicable to hernia and n = 10 to plastic/reconstructive surgery and involved patients of all Centers for Disease Control (CDC) wound classes and Ventral Hernia Working Group (VHWG) grades.ConclusionP4HB mesh provides long-term hernia repair strength and exhibits promising clinical outcomes beyond its resorption period. Future studies should include randomized controlled trials comparing P4HB to other biomaterials, as well as optimal patient selection, operative technique, long-term outcomes, minimization of potential mesh-related complications, and potential contraindications/complications for P4HB in hernia/abdominal wall reconstruction.
Prevalence of respiratory disease in Irish preweaned dairy calves using hierarchical Bayesian latent class analysis
Authors: Donlon John D. , Mee John F. , McAloon Conor G. 
Published: April 2023

IntroductionBovine respiratory disease (BRD) has a significant impact on the health and welfare of dairy calves. It can result in increased antimicrobial usage, decreased growth rate and reduced future productivity. There is no gold standard antemortem diagnostic test for BRD in calves and no estimates of the prevalence of respiratory disease in seasonal calving dairy herds.MethodsTo estimate BRD prevalence in seasonal calving dairy herds in Ireland, 40 dairy farms were recruited and each farm was visited once during one of two calving seasons (spring 2020 &amp; spring 2021). At that visit the prevalence of BRD in 20 calves between 4 and 6 weeks of age was determined using thoracic ultrasound score (≥3) and the Wisconsin respiratory scoring system (≥5). Hierarchical Bayesian latent class analysis was used to estimate the calf-level true prevalence of BRD, and the within-herd prevalence distribution, accounting for the imperfect nature of both diagnostic tests.ResultsIn total, 787 calves were examined, of which 58 (7.4%) had BRD as defined by a Wisconsin respiratory score ≥5 only, 37 (4.7%) had BRD as defined by a thoracic ultrasound score of ≥3 only and 14 (1.8%) calves had BRD based on both thoracic ultrasound and clinical scoring. The primary model assumed both tests were independent and used informed priors for test characteristics. Using this model the true prevalence of BRD was estimated as 4%, 95% Bayesian credible interval (BCI) (1%, 8%). This prevalence estimate is lower or similar to those found in other dairy production systems. Median within herd prevalence varied from 0 to 22%. The prevalence estimate was not sensitive to whether the model was constructed with the tests considered conditionally dependent or independent. When the case definition for thoracic ultrasound was changed to a score ≥2, the prevalence estimate increased to 15% (95% BCI: 6%, 27%).DiscussionThe prevalence of calf respiratory disease, however defined, was low, but highly variable, in these seasonal calving dairy herds.
Drosophila Models Reveal Properties of Mutant Lamins That Give Rise to Distinct Diseases
Authors: Walker Sydney G. , Langland Christopher J. , Viles Jill , Hecker Laura A. , Wallrath Lori L. 
Published: April 2023

Mutations in the LMNA gene cause a collection of diseases known as laminopathies, including muscular dystrophies, lipodystrophies, and early-onset aging syndromes. The LMNA gene encodes A-type lamins, lamins A/C, intermediate filaments that form a meshwork underlying the inner nuclear membrane. Lamins have a conserved domain structure consisting of a head, coiled-coil rod, and C-terminal tail domain possessing an Ig-like fold. This study identified differences between two mutant lamins that cause distinct clinical diseases. One of the LMNA mutations encodes lamin A/C p.R527P and the other codes lamin A/C p.R482W, which are typically associated with muscular dystrophy and lipodystrophy, respectively. To determine how these mutations differentially affect muscle, we generated the equivalent mutations in the Drosophila Lamin C (LamC) gene, an orthologue of human LMNA. The muscle-specific expression of the R527P equivalent showed cytoplasmic aggregation of LamC, a reduced larval muscle size, decreased larval motility, and cardiac defects resulting in a reduced adult lifespan. By contrast, the muscle-specific expression of the R482W equivalent caused an abnormal nuclear shape without a change in larval muscle size, larval motility, and adult lifespan compared to controls. Collectively, these studies identified fundamental differences in the properties of mutant lamins that cause clinically distinct phenotypes, providing insights into disease mechanisms.
946/1030 nm Dual-Wavelength Laguerre-Gaussian (LG01) Mode Vortex Laser Based on Intracavity Cascade Pumped Resonator
Authors: Yang Yashuai , Li Yongliang , Wang Chi , Yang Chao 
Published: April 2023

In this paper, the 946/1030 nm dual-wavelength LG01 mode vortex laser is obtained by applying the intracavity cascade pumped structure and annular-beam end-pumped method, an innovative and pioneering exploration of the transverse mode of the dual-wavelength laser. First, we demonstrate the oscillation characteristic theoretical model of the dual-wavelength LG01 mode laser, considering the reabsorption effect. Then the length of the laser crystal and the transmittance of the output mirror are simulated and analyzed, respectively, related to the oscillation characteristics of the 946 and 1030 nm LG01 mode vortex lasers. Finally, a 946/1030 nm LG01 mode vortex laser with the same handedness is successfully achieved in our experiment. With 20 W of annular-beam pump power, the output power of 946 and 1030 nm LG01 mode vortex lasers is 0.404 and 0.510 W, the slope efficiency is 3.6% and 6.2%, and the total optical-optical conversion efficiency is 4.6%. At the maximum output power, the fluctuations of output power within 1 h are 4.02% and 4.23%, and the beam quality factors M2 are 2.32 and 2.27, respectively, for 946 and 1030 nm LG01 mode vortex lasers. The wavefront phase exp(iϕ) of the 946/1030 nm dual-wavelength is also proved by the self-interference method.
O direito no contexto das relações sociais capitalistas / The right in the context of capitalist social relations
Authors: Teixeira Ana Paula Fernandes , Silva Leandro Luciano da 
Published: April 2023

As mudanças sociais e econômicas do século XIX, que se deram especialmente em razão dos movimentos de industrialização, formam um rico contexto para as investigações que se dão no campo da ciência do direito. Por um lado, há o aumento dos privilégios da burguesia e, por outro, a exploração da força de trabalho e, com ela, desemprego, baixos salários, desigualdade, miséria e aumento da proteção da propriedade privada, tudo sob o aval do Estado. O presente trabalho tem como objetivo revelar a base material do pensamento jurídico, no contexto das relações sociais capitalistas. Trata-se de revisão de literatura narrativa, tendo por objeto de análise os textos de Karl Marx, publicados na Gazeta Renana, no período de 25 de outubro a 3 de novembro de 1842, reunidos sob o título “Os despossuídos”, com nova publicação pela Editora Boitempo no ano de 2017. Verifica-se que, sob a perspectiva marxista, o direito moderno tem como função dar segurança às relações de troca, às relações de trabalho e à propriedade privada e, como tal, expressa-se como ordem jurídica dominante, embora tenha que regular relações sociais aparentemente distanciadas da reprodução econômico-social, como as relações familiares, o meio ambiente e os crimes. Ocorre que esse distanciamento não é senão uma aparência, dada por uma base doutrinária que termina levando à inferência equivocada de que o direito é um campo com autonomia absoluta em relação à reprodução social. Conclui-se que a doutrina política marxista apresenta um conjunto de elementos que revelam o direito como um instrumento de promoção de abstração do sujeito jurídico da realidade social, proclamando uma igualdade jurídica apenas formal, além de ser um reflexo das necessidades e dos interesses da classe dominante.