bluuebunny/crossref_metadata_2025_split huggingface dataset:
Status of transjugular intrahepatic portosystemic shunt for portal hypertension in China: A national survey analysis
Authors: Shao Haibo , Han Xinwei , Zhao Jianbo , Sun Junhui , Fang Zhuting , Xiong Bin , Zhu Xiaoli , Ren Weixin , Yuan Min , Yu Shiping , Niu Meng , Lv Weifu , Zhang Xueqiang , Zhang Chunqing , Li Lei , Luo Xuefeng , Song Yusheng , Ma Yilong , Dang Tong , Xiang Hua , Jin Yun , Xue Hui , Jin Guiyun , Li Xiao , Li Jiarui , Zhou Shi , Yu Changlu , He Song , Yu Lei , Zu Hongmei , Ma Jun , Lei Yanming , Xu Ke , Qi Xiaolong ,   CHESS‐TIPS consortium
Published: March 2023

AbstractAimThe transjugular intrahepatic portosystemic shunt (TIPS) procedure has been performed in China for 30 years, but our understanding of the status and difficulties associated with the use of TIPS for portal hypertension is incomplete. This study aims to investigate the current situation of the use of TIPS for portal hypertension, which should aid the development of TIPS in China.MethodsThis study involved a questionnaire survey, initiated by the China Portal Hypertension Alliance (CHESS) to investigate the use of TIPS for portal hypertension in China. Questionnaires were released on the Internet between August 16, 2022 and September 16, 2022. Detailed information was collected from 545 hospitals contracted by the CHESS in China, which performed TIPS surgery in 2021.ResultsThe 545 hospitals covers the majority of hospitals in China that conduct TIPS intervention. In the survey, a total of 13,527 TIPS interventions were carried out with 94.1% (498/545) of them had a system of routine follow‐up after TIPS. The majority (42.6% [232/545]) believed that the main indication of TIPS was the control of acute bleeding. Overall, 48.1% (262/545) carried out early or pre‐emptive TIPS, 53.0% (289/545) carried out TIPS for cavernous transformation of the portal vein, and 81.0% (441/545) chose routine embolization of collateral circulation during operation. Most used coils (97.0% [475/490]) and biological glue (72.0% [353/490]) as embolic materials, and 78.5% (428/545) routinely performed intraoperative portal pressure gradient measurements. When selecting TIPS stents, 57.1% (311/545) chose viator‐specific stents, and 57.2% (312/545) chose conventional anticoagulation after TIPS. Conventional anticoagulation after TIPS is over a time interval of 3–6 months (55.4% [173/312]). The limitation of TIPS surgery is mainly its cost (72.3% [394/545]) and insufficient understanding of the procedure by doctors in other related departments (77.4% [422/545]). Most of the hospital teams accept the use of domestic instruments in TIPS surgery (92.7% [505/545]).ConclusionsThis survey shows that TIPS is an essential part of the treatment of portal hypertension in China. TIPS is widely used in Chinese patients with portal hypertension, and this survey presents a more comprehensive picture of the options and difficulties encountered in the implementation of TIPS. In the future, it is necessary to promote TIPS technology and further standardize surgical indications, routine operations, and instrument application.
Investigating the potential of civil disagreement to decrease issue polarization in China
Authors: Guan Tianru , Liu Tianyang , Chen Xiaotong 
Published: March 2023

AbstractWith mass polarization becoming an increasingly urgent sociopolitical agenda in both established and emerging democracies, academics and policy‐makers have been racing to develop effective depolarizing approaches. While (semi‐)authoritarian nations have also been afflicted by social cleavage and a negative, incompatible and even radicalized discussion climate towards public policy and sociopolitical issues, polarization and related countermeasures in such contexts have thus far gained scarce academic attention. The present study addresses this gap, investigating the depolarization potential of exposure to civil (vs. uncivil) cross‐cutting discussion in China's cyberspace. Through online experiment (N = 1064), participants were exposed to dissonant viewpoints on China's contentious divorce‐cooling‐off‐period policy, presented as original Weibo posts (China's social network site). Our results prove the effectiveness of civil disagreement, as a virtue and precondition of deliberation, in alleviating opinion extremity. Finally, implications for China's wider political system and deliberation studies are discussed.
Monitoring and reporting dam safety operational risks based on bow tie methodology
Authors: Alves Douglas , Oliveira Cristiano Francisco , Marsal Sergio Claudio , Souza Rubenei Novais , Fonseca Luiz Paulo Carvalho 
Published: March 2023

AbstractThis work focuses on the development of an approach considering the application of the bow tie methodology for monitoring and reporting the performance status of safety barriers used in collapse prevention of dams that store water for refinery process purposes, as well as for mitigation of the consequences in case of materialization of this scenario. After elaboration of the bow tie diagram in collaboration with technical specialists directly involved in dams' safety, the integrity of barriers is determined based on information collected from each dam at an operational level. Considering the literature review carried out, one of the most important contributions of this research (besides the bow tie diagram itself) consists in the proposition of a periodic reporting process of barriers performance indicators to managers responsible for each barrier in order to properly support risk management, permeating all the relevant technical and hierarchical levels (including communications upwards the board—top management). Its main motivation lies in lessons learned from several past major accidents, such as Macondo, Texas City, and, the Brumadinho catastrophe itself, regarding the need for safety information to “travel upwards” on the companies' hierarchy in order to properly and quickly support the decision‐making process, contributing to the strengthening of safety culture inside the organizations.
Bounded integer model‐based analysis of psoriasis area and severity index in patients with moderate‐to‐severe plaque psoriasis receiving BI 730357
Authors: Ooi Qing Xi , Kristoffersson Anders , Korell Julia , Flack Mary , L. Plan Elodie , Weber Benjamin 
Published: March 2023

AbstractBI 730357 is investigated as an oral treatment of plaque psoriasis. We analyzed the impact of three dosage regimens on the Psoriasis Area and Severity Index (PASI) response with modeling based on phase I and II data from 109 healthy subjects and 274 patients with moderate‐to‐severe plaque psoriasis. The pharmacokinetics (PK) was characterized by a two‐compartment model with dual absorption paths and a first‐order elimination. Higher baseline C‐reactive protein was associated with lower clearance and patients generally had lower clearance compared with healthy subjects. A bounded integer PK/pharmacodynamic model characterized the effect on the observed PASI. The maximum drug effect was largest for patients with no prior biologic use, smaller for patients with prior use of non‐interleukin‐17 inhibitors, and smallest for patients with prior interleukin‐17 inhibitor use. The models allowed robust simulation of large patient populations, predicting a plateau in PASI outcomes for BI 730357 exposure above 2000 nmol/L.
Rose essential oil diminishes dopaminergic neuron degenerations and reduces α‐synuclein aggregation in Caenorhabditis elegans models of Parkinson's disease
Authors: Muhammad Fahim , Liu Yan , Wang Ningbo , Zhao Longhe , Zhou Yangtao , Yang Hui , Li Hongyu 
Published: March 2023

AbstractParkinson's disease (P.D.) is the second most progressive neurodegenerative disorder in the elderly. Degeneration of dopaminergic (DA) neurons and α‐synuclein (α‐Syn) accumulated toxicity is the major contributor to this disease. At present, the disease has no effective treatment. Many recent studies focus on identifying novel therapeutics that provide benefits to stop the disease progression in P.D. patients. Screening novel and effective drugs in P.D. animal models is time‐ and cost‐consuming. Rose Essential Oil (REO) extracted from Rosa Rugosa species (R. Setate × R. Rugosa). REO contains Citronellol, Geraniol, and Octadiene that possess anti‐Aβ, anti‐oxidative, and anti‐depression‐like properties, but no reports have defined the REO effect on P.D. yet. The present study examines the REO neuroprotective potential in transgenic Caenorhabditis elegans P.D. models. We observed that REO reduced α‐Syn aggregations and diminished DA neuron degenerations induced by 6‐OHDA, reduced food‐sensing behavioural disabilities, and prolonged the lifespan of the nematode. Moreover, REO augmented the chymotrypsin‐like proteasome and SOD‐3 activities. Further, we observed the anti‐oxidative role of REO by reducing internal cells ROS. Together, these findings supported REO as an anti‐PD drug and may exert its effects by lowering oxidative stress via the anti‐oxidative pathway.
Robust H∞ tracking of linear discrete‐time systems using Q‐learning
Authors: Valadbeigi Amir Parviz , Shu Zhan , Khaki Sedigh Ali 
Published: March 2023

AbstractThis paper deals with a robust tracking problem with a discounted factor. A new auxiliary system is established in terms of norm‐bounded time‐varying uncertainties. It is shown that the robust discounted tracking problem for the auxiliary system solves the original problem. Then, the new robust discounted tracking problem is represented as a well‐known zero‐sum game problem. Moreover, the robust tracking Bellman equation and the robust tracking Algebraic Riccati equation (RTARE) are inferred. A lower bound of a discounted factor for stability is obtained to assure the stability of the closed‐loop system. Based on the auxiliary system, the system is reshaped in a new structure that is applicable to Reinforcement Learning methods. Finally, an online Q‐learning algorithm without the knowledge of system matrices is proposed to solve the algebraic Riccati equation associated with the robust discounted tracking problem for the auxiliary system. Simulation results are given to verify the effectiveness and merits of the proposed method.
Satellite constellation design for 5G wireless networks of mobile communications
Authors: Muttiah Ravandran 
Published: March 2023

SummarySatellite constellation design plays an important role in satellite networks. Network constellation system design can affect the effectiveness of current improvements of the communications link and the management of the entire network. The power requirement of the mobile stations and ground stations is very high in a geostationary Earth orbit communication system, which means the terrestrial terminal is hard to be made handheld for fifth generation mobile communications. The emergence of nongeostationary orbit satellites such as low Earth orbit satellites greatly compensates for the disadvantage of geostationary Earth orbit satellites. Based on the classical constellation design method, the orthogonal circular orbit constellation is proposed. The design objectives considered here are the following: global Earth coverage by low Earth orbit satellites, the duration of continuously covering one mobile station by one satellite is more than 9.57 min, the access satellite link duration time of the mobile station is more than 4.79 min, and the number of satellites and orbits is to be minimum.
In Situ Formation ZnIn2S4/Mo2TiC2 Schottky Junction for Accelerating Photocatalytic Hydrogen Evolution Kinetics: Manipulation of Local Coordination and Electronic Structure
Authors: Xi Qing , Xie Fangxia , Liu Jianxin , Zhang Xiaochao , Wang Jiancheng , Wang Yawen , Wang Yunfang , Li Houfen , Yu Zhuobin , Sun Zijun , Jian Xuan , Gao Xiaoming , Ren Jun , Fan Caimei , Li Rui 
Published: March 2023

AbstractRegulating electronic structures of the active site by manipulating the local coordination is one of the advantageous means to improve photocatalytic hydrogen evolution (PHE) kinetics. Herein, the ZnIn2S4/Mo2TiC2 Schottky junctions are designed to be constructed through the interfacial local coordination of In3+ with the electronegative O terminal group on Mo2TiC2 based on the different work functions. Kelvin probe force microscopy and charge density difference reveal that an electronic unidirectional transport channel across the Schottky interface from ZnIn2S4 to Mo2TiC2 is established by the formed local nucleophilic/electrophilic region. The increased local electron density of Mo2TiC2 inhibits the backflow of electrons, boosts the charge transfer and separation, and optimizes the hydrogen adsorption energy. Therefore, the ZnIn2S4/Mo2TiC2 photocatalyst exhibits a superior PHE rate of 3.12 mmol g−1 h−1 under visible light, reaching 3.03 times that of the pristine ZnIn2S4. This work provides some insights and inspiration for preparing MXene‐based Schottky catalysts to accelerate PHE kinetics.
Strong Ferromagnetic Manipulation of SrTiO3 from CO2‐Straining Effect on Electronic Structure Modulation
Authors: Li Lianyu , Gao Bo , Xu Song , Xu Qun 
Published: March 2023

Abstract2D magnetic materials are ideal to fabricate magneto‐optical, magneto‐electric, and data storage devices, which are proposed to be critical to the next generation of information technologies. Benefited from their labile structures, 2D perovskites are amenable for magnetic manipulation through structural optimization. In this work, 2D room‐temperature ferromagnetic SrTiO3 is achieved through straining effect induced by supercritical carbon dioxide (SC CO2). According to experimental results, the cubic phase of SrTiO3 is converted to tetragonal with exposure of (110), (200), (111), and (211) planes over the SC CO2 treatment, leading to significant ferromagnetic enhancement. Theoretical calculations illustrate that over the conversion from cubic to tetragonal, the electronic structure of SrTiO3 is significantly modulated. Specifically, the spin density of planes of (200), (111), and (211) is enhanced, presumably due to the stabilization of the highest occupied molecular orbital over straining by SC CO2, leading to magnetic optimizations. This work suggests that magnetic optimization can be achieved from SC CO2‐induced electronic structure modulation.
Reading the Word and World: Portrayals of Activism in Children's Literature
Authors: Fletcher Lauren , Holyoke Erica 
Published: March 2023

AbstractActivism is a term used frequently within and beyond educational settings, but the term is not always clearly defined. Using content analysis of over 150 picturebooks depicting activism, we strive to provide specificity to what activism is and make it tangible for readers and teachers. Through content analysis, we investigate key themes, characters, and actions in these books. From this analysis, we present a framework of head, heart, and world books. This framework illuminates the nuances of what activism can be from every day to transformative actions in making communities, local and global, a more equitable place. The article emphasizes the importance of using a variety of picturebooks on activism in classrooms to empower teachers and children to think critically about texts and be changemakers in the world.
Minimum space requirements for cattle: An approach based on photographic records
Authors: Gallo Carmen , Tabilo Bárbara , Navarro Grisel , Phillips Clive 
Published: March 2023

AbstractBackgroundThe space requirements for accommodating cattle during confinement are based on assessment of both the physical space occupied by the animals and that needed for essential behaviours. The aim of this study was to estimate the area (m2) occupied by cattle of different liveweights in the static standing (ST), recumbency (SR) and sleeping (SL) postures.MethodsThe study was conducted in Chile. The area (m2) occupied by 26 female beef cross cattle with liveweights between 45 and 642 kg was estimated in the ST, SR and SL postures through planimetry using overhead photographs. The allometric coefficientkvalue was obtained for each posture using linear regression equations from the measured weight (kg0.66) and area occupied.ResultsLess but more variable space was occupied by each individual in the ST posture compared to SR or SL posture, with clear correlations between weight and occupied area. Thekvalues obtained were 0.014 (ST), 0.023 (SR) and 0.021 (SL), which are all less than international recommendations for the same postures.LimitationsThe methodology needs refinement to reduce the distance to the object optical effect in the different postures. Further work is also needed to determine additional space requirements for behavioural needs and movements associated with each posture and change of posture, depending on the type of confinement.ConclusionsWe provide a scientific basis on which to objectively establish absolute minimum static space requirements for cattle of different breeds, types, weights and anatomical conformations and calculatekvalues.
Ovine endometrial estrogen receptor expression is altered following PG‐600 administration
Authors: Habeeb Hayder Mohammed Hassan , Kleditz Logan , Hazzard Timothy , Bishop Cecily , Stormshak Fred , Kutzler Michelle Anne 
Published: March 2023

AbstractBackgroundDysregulation of the estrogen receptor 1 (ESR1) expression during the establishment of pregnancy could contribute to reduce fertility reported in ewes treated with PG‐600.ObjectivesThe objective of this study was to evaluate the effect of treatment with PG‐600 on ESR1 expression in the ovine endometrium during early diestrus.MethodsPolypay ewes (n = 24) that had exhibited an oestrous cycle of normal duration (16–18 days) were treated with intravaginal progesterone‐releasing device (CIDR) for 9 days. Cloprostenol was administrated two days before CIDR withdrawal. On the day of CIDR withdrawal (day 0), ewes received a 5 mL intramuscular injection of PG‐600 (400 IU equine chorionic gonadotropin and 200 IU human chorionic gonadotropin) or saline. Blood samples were collected before treatment and on the day of tissue collection to determine serum estradiol‐17β and progesterone concentrations using radioimmunoassay. On days 4 and 7, six ewes from each treatment group were anaesthetised and a laparotomy was performed to obtain intercaruncular endometrial samples. Endometrial samples were collected ipsilateral to the ovary bearing the highest number of corpora lutea. An estradiol exchange assay was used to determine ESR1 concentration.ResultsEstradiol concentrations did not differ by time or treatment, but progesterone concentrations were significantly higher in the PG‐600‐treated group on day 7 despite a similar number of corpora lutea. Endometrial ESR1 concentration was significantly reduced on day 7 in the PG‐600 group.ConclusionsIn conclusion, although progesterone was higher than controls on day 7, ESR1 did not differ from controls suggesting that treatment with PG600 is unlikely to impair reproductive potential.
Dynamics of magnetohydrodynamic nonlinear radiative flow of diamond‐Co3O4/EG hybrid nanofluid with homogeneous—heterogeneous reactions
Authors: Jehan Saiqa Shah , Khan Waris , Fadhl Bandar M. , Makhdoum Basim M. , Abbas Zaheer 
Published: March 2023

AbstractNewtonian fluid flow analysis is quickly becoming one of the most important areas of study. These liquids have an extensive range of engineering and industrial uses, including in cooling systems, food processing, nuclear reactors, paint and adhesives, and drilling rigs. Hybrid nanofluids, on the other hand, are vital to the heat transmission process. This research aims to examine the hybrid nanofluid's three‐dimensional nonlinear radiative magnetohydrodynamic flow over a stretching surface. Ethylene glycol is considered a base fluid, whereas diamond and Cobalt tetroxide (Co3O4) are considered hybrid nanoparticles. The approach also takes into account the catalytic property of homogeneous—heterogeneous processes. The governing fluid equations are computed by Homotopy analysis method and compare the result with shooting technique after employing appropriate transformations. The result of different constraints on temperature profiles and velocity profiles are scrutinized and graphically depicted as well as through the construction of table. A graphical comparison has been made between Nusselt number and skin friction for hybrid nanofluid and nanofluid respectfully. The finding of our study is that the velocity profile decreases for the high value of magnetic parameter. In the presences of nonlinear radiation temperature profile enhances. In transferring heat, the hybrid nanofluid is more effective than nanofluid. This work can be used in various industries to increase their efficiency.
Numerical analysis of nonlinear time‐fractional fluid models for simulating heat transport processes in porous medium
Authors: Khan Mumtaz , Rasheed Amer , Anwar Muhammad Shoaib 
Published: March 2023

AbstractHybrid nanomaterials offer potential scope for increasing numerous novel applications when engineered to deliver availably functional properties. In the current assessment, a novel fractional constitutive relationship for buoyance‐driven flow and heat transfer has been developed in order to control the flow and heat transfer behavior. The fluid flow is produced by a permeable moving surface and is exposed to thermal radiation along with an applied magnetic field. This study employed the SiO2/MoS2 hybrid nanoparticles with different mass ratios in water as the base fluid. Moreover, the Darcy expression characterizes the porous spaces with variable porosity and permeability. Governing fractional PDEs are nonlinear and solved numerically with finite‐difference discretization and the L1‐ algorithm. The results show that heat transfer rate enhanced 8% by enhancing the thermal fractional parameter. It is also found that the combination of two nanoparticles in water significantly contributes to heat transfer compared to the presence of a single particle. Further, thermal radiation significantly contributes to heat transfer in fluid flow. Not surprisingly, hybrid particles have excellent performance at high loads and diverse velocity cases.
White Fluff/Black Pigment: Health Commodity Culture and Victorian Imperial Geographies of Dependence
Authors: Pietrzak-Franger Monika 
Published: March 2023

AbstractVictorian travel, like larger patterns of migration, was associated with a myriad of health hazards that were often seen as dangerous to the “civilisational mission” of the British Empire and its economic aspirations. Within this context, specific prescriptive regimes and consumer practices—and, with them, hand-selected “tropical outfits”—provided a portablecordon sanitaireto travellers, explorers, and the “builders” of the British Empire. Tropical outfits—a variety of objects expertly selected for the voyage—were sold with the intention of “easing” the journey’s hardships while inevitably also propelling the exchange of goods between the metropolitan centre and the colonies. This chapter re-evaluates the role of “tropical outfits”, especially “tropical clothing”, by drawing attention to their material significance within the colonial but also domestic geographies of health and disease. Monika Pietrzak-Franger argues that the juxtaposition of the outfits’ sites of consumption with those of their production sheds light on the transcontinental networks of health and disease that otherwise remain obscured.