bluuebunny/crossref_metadata_2025_split huggingface dataset:
Source, pattern and flux of dissolved carbon in an alpine headwater catchment on the eastern Tibetan Plateau
Authors: Liu Dong , Wang Tao , Liu Xinyu , Ao Jing , Tang Haiping , Chang Ruiying 
Published: July 2023

AbstractDissolved carbon (DC) transported from headwater streams on the eastern Tibetan Plateau is a crucial component of the carbon cycles in the regional river. However, the spatiotemporal variability and sources of DC in these remote headwater streams remains unclear. An investigation into dissolved organic carbon (DOC) and dissolved inorganic carbon (DIC) was conducted with high temporal resolution from a glacier terminus, a forest catchment, and the catchment outlet located on the eastern flank of Mt. Gongga, Southwest China. The results showed that (1) the mean DOC concentration at the glacier terminus (2.38 ± 0.71 mg L−1) was significantly higher than at the forest catchment (2.13 ± 0.49 mg L−1) and at the catchment outlet (2.17 ± 0.58 mg L−1), while the DIC concentration increased by 21.6% at the forest catchment and by 18.7% at the catchment outlet relative to that in the glacier terminus. (2) Compared to the monsoon season, DOC concentrations in the forest catchment decreased by 24.6% postmonsoon, and the seasonal variation of DOC concentrations was minor either at the glacier terminus or at the catchment outlet; relative to monsoon values, postmonsoon DIC concentrations increased by 14.9% and 28.8% at the forest catchment and catchment outlet, respectively. Precipitation and stream pH were identified as important factors influencing the seasonal variability of DC. (3) Silicate and carbonate weathering contributed 52.9 ± 12% and 44.4 ± 9%, respectively, to DIC generation in the forest catchment according to 13C analysis. This study provides a valuable dataset on the dynamics of DC in a region where data is sparse, which improves our understanding of DC transport in alpine regions. The unexpected spatiotemporal stability of DC suggests that less frequent rates of sampling might be adequate to estimate carbon export.
A Surrogate Model Approach for Studying Performance and Cycle Time in Complex System Development
Authors: Chiesi Stephanie Sharo , Grogan Paul T. 
Published: July 2023

AbstractThis paper presents a surrogate model approach to advance fundamental research on understanding impacts of engineering decision‐making on complex system performance and system development cycle times. The approach is motivated by digital transformation and advancement of the digital engineering strategy by the U.S. Department of Defense as part of acquisition modernization. The digital engineering strategy focuses on five goals as a means to reduce acquisition cycle times and increase capability deployment to the warfighter, but we lack the theory to understand the impact of the digital transformation on engineering processes, decision‐making and the solution performance. The surrogate model approach discussed herein could provide a methodology for studying the impact of digital engineering on solution performance and lifecycle development time on a wide class of design problems with tunable complexity.
Inconsistent and Incomplete Datasheet: The case for systematic use of requirement engineering
Authors: Brisacier‐Porchon Lorraine , Hammami Omar 
Published: July 2023

AbstractThe lifecycle of a system is extended from its early conception to its retirement of service. The lifespan of Unmanned Ground Vehicles (UGVs) can be expected to last over 50 years in the defense market. In this context, the rising complexity of UGV systems imposes engineering steps that would ensure both capabilities of the system and resilience to its future inclusion in a system‐of‐system context. During its operational usage, the UGV is supposed to be maneuvered for specifically designed purposes following user manual datasheet of the components off‐the‐shelf (COTS) that were integrated. This paper exposes the public user datasheet relevance compared to the system engineering requirements that are the artifacts of system design architecture. The use of connecting COTS user manual to system requirements is discussed, all the more if the systems are to be re‐used in a system production line. This article is intended to explore system of system conception methods for future robotized battlefield.
Internalization of extracellular vesicles from Lactobacillus johnsonii N6.2 elicit an RNA sensory response in human pancreatic cell lines
Authors: da Silva Danilo R. , Gonzalez Claudio F. , Lorca Graciela 
Published: July 2023

AbstractCells of all domains of life can secrete extracellular vesicles (EV). These secreted vesicles have been indicated as vehicles carrying molecules that facilitate intra‐ and inter‐species interaction. Lactobacillus johnsonii N6.2, a bacterium used in probiotic preparations, has been shown to produce nano‐sized EV. In the present work we used L. johnsonii N6.2 EV, concentrated from exosome‐depleted MRS supernatant, to identify the uptake mechanisms of EV and the impact of the RNA cargo in the EV on the upregulation of the cellular response of βlox5 human pancreatic cells. Using eukaryotic uptake inhibitors, it was found that EV are internalized by the clathrin/dynamin mediated endocytosis pathway. Further co‐localization experiments with the endosome markers RAB5, RAB7 and LAMP1 as well as calcein indicated that EV escape the endosome shortly after RAB7 fusion. Using the expression of the 2′,5′‐oligoadenylate synthetase (OAS) host pathway, previously identified as targeted by L. johnsonii EV, we found that the host cellular response to the EV are dependent on the integrity of the external components of the EV as well as on the RNA cargo. Global transcriptome analysis was performed on EV and the bacterial whole cell. It was found that the RNA transcripts found within the EV largely represent the most abundantly transcribed genes in the bacterial cells such as those associated with protein synthesis and glycolysis. Further analysis showed an enrichment of smaller size transcripts as well as those encoding for membrane bound or extracellular proteins in L. johnsonii’s EV.
The pivotal role of high‐resolution mass spectrometry in the study of grape glycosidic volatile precursors for the selection of grapevines resistant to mildews
Authors: De Rosso Mirko , Panighel Annarita , Migliaro Daniele , Possamai Tyrone , De Marchi Fabiola , Velasco Riccardo , Flamini Riccardo 
Published: July 2023

AbstractA breeding program to produce new grape varieties tolerant to main vine fungal pathogens (Plasmopara viticola and Erysiphe necator) is carrying out by crossing Vitis vinifera cv. “Glera” with resistant genotypes such as “Solaris,” “Bronner,” and “Kunleany.” Firstly, resistance gene‐based markers analyses allowed the identification of five genotypes, which have inherited the resistance loci against mildews. To select those that also inherited the phenotype as close as possible to ‘Glera’ suitable to be introduced in the Prosecco wine production protocols, the grape glycosidic derivatives were studied by UHPLC/QTOF mass spectrometry. Targeted identification of the metabolites was performed using a database expressly constructed by including the glycosidic volatile precursors previously identified in grape and wine. A total of 77 glycosidic derivatives including many aroma precursors and some variety markers, were identified. Original resistant genotypes had distinct metabolomic profiles and different to ‘Glera’, while the crossings showed varying similarity degrees to V. vinifera parent. Findings demonstrated the Glera × Bronner and Glera × Solaris crossings are more suitable to produce high‐sustainable Prosecco wines. Coupling of glycosidic volatile precursors profiling to multivariate statistical analysis was effective for phenotypic characterization of grapes and to evaluate their enological potential.
Children's Oncology Group's 2023 blueprint for research: Pharmacy
Authors: Ostrenga Andrew R. , Thackray Jennifer , McLearan Ha‐Mill H. , Mulieri Kevin M. , Bisaccia Elizabeth , Militano Olga , Dupuis L. Lee , Bernhardt M. Brooke ,   the COG Pharmacy Discipline Steering Committee
Published: July 2023

AbstractChildren's Oncology Group (COG) pharmacists and pharmacy technicians from more than 200 COG‐member institutions comprise the COG Pharmacy Discipline. Discipline members serve an essential role in the design and execution of COG clinical trials. Core activities include study drug management, study drug access, clinical trial operations, protocol harmonization, and direct patient care. Discipline members are also actively involved in continuing education, membership engagement, and research across other COG committees/domains. Future areas of committed growth for the discipline include pharmacogenomics, pharmacokinetics, pharmacoeconomics, pharmaceutics, and implementation science.
Thermal and morphological characterization of biowaste date palm fiber‐reinforced polybenzoxazine and epoxy composites
Authors: Abdelkawy Mahmoud A. , Itsuno Shinichi , El‐Badawi Mahmoud A. , Aly El‐Saied A. 
Published: July 2023

AbstractWaste date palm fiber (DPF) has recently emerged as a promising natural fiber due to its abundance, renewability, and low cost. The study discussed the use of DPF as reinforcement in composites, particularly in polybenzoxazine (PBz), epoxy resin (EP), and their copolymer (EP‐co‐PBz) composites. The waste DPF underwent an alkaline treatment process, resulting in a high‐performance material that exhibits exceptional interaction with the matrix. The composite samples were fabricated using 5–20 wt% of alkali treated DPFs with polybenzoxazines and epoxy resins. The study examined the thermal and morphological properties of the resulting composites and found that they exhibited remarkable enhancements in various properties. For instance, the PNaphz‐COOH reinforced 5 wt% DPFs composite showed a significant increase in Td5% and Td10%, while the EP‐co‐PBz reinforced DPFs composites exhibited a remarkable increase in char yield (Yc). The SEM analysis of the composite surface further validated these findings, highlighting the remarkable interfacial bonding between the DPFs and the matrix. The remarkable enhancements in thermal properties demonstrated in this study open up new possibilities for utilizing waste DPF in various applications.Highlights
Waste date palm fiber enhances thermosetting polymer reinforcement for high‐performance composites.
Alkaline treatment improves interfacial bonding between waste DPF and matrix.
Composites reinforced with waste DPF exhibit outstanding thermal and morphological properties.
How research on persuasion can inform dual-process models of judgment
Authors: Petty Richard E. , Wegener Duane T. , Briñol Pablo 
Published: July 2023

Abstract
De Neys makes some useful points regarding dual-process models, but his critique ignores highly relevant theories of judgment from the persuasion literature. These persuasion models predate and often circumvent many of the criticisms he makes of the dual-process approaches he covers. Furthermore, the persuasion models anticipated some of the correctives to dual-process models that he proposes.
Toward dual-process theory 3.0
Authors: Frankish Keith 
Published: July 2023

Abstract
This commentary is sympathetic to De Neys's revision of dual-process theory but argues for a modification to his position on exclusivity and proposes a bold further revision, envisaging a dual-process theory 3.0, in which system 1 not only initiates system 2 thinking but generates and sustains it as well.
Ethnomusicology, entrepreneurialism and the Western classical music student
Authors: Avis Rupert 
Published: July 2023

AbstractThis article explores the potential use of ethnomusicology in the development of entrepreneurialism amongst Western classical music students studying at UK music colleges. It is argued that both ‘doing’ and ‘reading’ ethnomusicology can encourage students to explore the diverse uses and meanings attached to Western classical music in varied social and geographic contexts. The knowledge garnered through ethnomusicology can then be applied in creative, informed and situational ways by students in the development of entrepreneurial strategies. As a by-product, it is suggested that ethnomusicology can be used to reframe entrepreneurialism as a musical, relational and interactive process.
Advantages of GSMaP Data for Multi‐Timescale Precipitation Estimation in Luzon
Authors: Lee Cheng‐An , Huang Wan‐Ru 
Published: July 2023

AbstractThe Global Precipitation Measurement Mission (GPM) provides two different sources of post‐real‐time satellite‐based rainfall estimates, including the Integrated Multi‐satellitE Retrievals for GPM Final Run (herein IMERG‐F) and Global Satellite Mapping of Precipitation‐Gauge (herein GSMaP‐G). However, relative to IMERG‐F, GSMaP‐G has been less thoroughly evaluated in the context of studying rainfall variations over Luzon, Philippines. Using rain‐gauge observations over Luzon as a reference base, this study aimed to clarify if GSMaP‐G v07 is more capable than IMERG‐F v06 in regard to representing rainfall variations over Luzon at multiple timescales (including intraseasonal, annual, and interannual). The results revealed that both IMERG‐F and GSMaP‐G performed better in regard to depicting the temporal phase evolution for the wet season rainfall than they did for the dry season rainfall for Luzon. However, relative to IMERG‐F, GSMaP‐G exhibited better performance in most examined features, including (a) the detection of temporal variations (both phase and amplitude) of rainfall on the intraseasonal, annual, and interannual timescales; (b) the representation of spatial differences with more rainfall occurring from April to September for western Luzon and from October to March for eastern Luzon; (c) the detection of occurrence of rainfall events at various intensities. The analysis also demonstrates that the difference between the performance of IMERG‐F and GSMaP‐G in regard to quantitative rainfall estimation is larger during the wet season than it is during the dry season. The possible cause for their performance differences over Luzon is the differences in the gauge‐adjustment method and the biases in its pre‐non‐gauge‐adjusted product.
Ride comfort and segmental vibration transmissibility analysis of an automobile passenger model under whole body vibration
Authors: Guruguntla Veeresalingam , Lal Mohit , Ghantasala G. S. Pradeep , Vidyullatha P. , Alqahtani Malak S. , Alsubaie Najah , Abbas Mohamed , Soufiene Ben Othman 
Published: July 2023

AbstractThe examination of seated occupants’ ride comfort under whole-body vibration is a complex topic that involves multiple factors. Whole-body vibration refers to the mechanical vibration that is transmitted to the entire body through a supporting surface, such as a vehicle seat, when traveling on rough or uneven surfaces. There are several methods to assess ride comfort under whole-body vibration, such as subjective assessments, objective measurements, and mathematical models. Subjective assessments involve asking participants to rate their perceived level of discomfort or satisfaction during the vibration exposure, typically using a numerical scale or questionnaire. Objective measurements include accelerometers or vibration meters that record the actual physical vibrations transmitted to the body during the exposure. Mathematical models use various physiological and biomechanical parameters to predict the level of discomfort based on the vibration data. The examination of seated occupants ride comfort under whole-body vibration has been of great interest for many years. In this paper, a multi-body biomechanical model of a seated occupant with a backrest is proposed to perform ride comfort analysis. The novelty of the present model is that it represents complete passenger by including thighs, legs, and foot which were neglected in the past research. A multi-objective firefly algorithm is developed to evaluate the biomechanical parameters (mass, stiffness and damping) of the proposed model. Based on the optimized parameters, segmental transmissibilities are calculated and compared with experimental readings. The proposed model is then combined with a 7-dofs commercial car model to perform a ride comfort study. The ISO 2631-1:1997 ride comfort standards are used to compare the simulated segmental accelerations. Additionally, the influence of biomechanical parameters on most critical organs is analyzed to improve ride comfort. The outcomes of the analysis reveal that seated occupants perceive maximum vibration in the 3–6 Hz frequency range. To improve seated occupants' ride comfort, automotive designers must concentrate on the pelvis region. The adopted methodology and outcomes are helpful to evaluate protective measures in automobile industries. Furthermore, these procedures may be used to reduce the musculoskeletal disorders in seated occupants.
Nevus Spilus With Dermatoheliosis: A Histologic Mimicker of Melanoma in Situ at Melanoma Excision Margins
Authors: Sheridan Connor , O'Connor Megan C. , Sitton Beau , Bass Jonathan , Shahwan Kathryn T. , Carr David R. 
Published: July 2023

Abstract:
Nevus spilus, or speckled lentiginous nevus, is a relatively common lesion that presents at birth or in early childhood. It consists of a background tan patch, which appears similar to a café au lait macule or lentigo simplex on histology, studded with various types of nevi. Rarely, these nevi can undergo malignant transformation to melanoma. When melanoma develops within a heavily photodamaged nevus spilus, evaluating excision margins may be challenging because the combined histologic features of nevus spilus and severe dermatoheliosis can mimic melanoma in situ. We report a case of an elderly man with extensive sun damage who developed malignant melanoma within an occult nevus spilus, resulting in multiple excisions with false-positive margins.
BILATERAL RETINAL HEMORRHAGES AFTER SEQUENTIAL ENDOVASCULAR TREATMENT OF BILATERAL UNRUPTURED CEREBRAL ANEURYSMS
Authors: Liu Tianyu , Tsui Jonathan C. , Choudhri Omar A. , Kim Benjamin J. , Brucker Alexander J. 
Published: July 2023

Purpose:
To report a case of bilateral retinal hemorrhages in a patient undergoing two separate endovascular interventions for bilateral cerebral aneurysms.

Methods:
A comprehensive ophthalmic examination was performed after the patient underwent each of two separate endovascular interventions for bilateral cerebral aneurysms. Multimodal imaging including widefield pseudocolor fundus photography, optical coherence tomography, and widefield fluorescein angiography was obtained. A systemic workup including genetic testing and hypercoagulability studies was performed.

Results:
Dilated fundus examination revealed new visually significant ipsilateral retinal hemorrhages after each endovascular procedure. Fluorescein angiography showed evidence of a peripheral retinal microangiopathy present in both eyes before the patient underwent her second endovascular procedure. Systemic workup revealed persistently elevated serum anticardiolipin IgM antibody levels at >99th percentile.

Conclusion:
Retinal complications after endovascular intracranial interventions are uncommon. This patient who developed bilateral retinal complications was found to have persistently elevated anticardiolipin antibody levels, a risk factor for thrombosis. Patients who develop retinal complications after endovascular intracranial intervention may benefit from systemic workup for hypercoagulable conditions.
FUNGAL ENDOPHTHALMITIS MASQUERADING AS SYMPATHETIC OPHTHALMIA
Authors: Hang Abraham , Ruiz Jonathan , Park Susanna S. , Homer Natalie A. , Kim Esther , Moussa Kareem 
Published: July 2023

Purpose:
To describe the ocular pathology of a patient with fungal endophthalmitis with features mimicking sympathetic ophthalmia.

Methods:
Review of medical records and histopathology of a single patient.

Results:
A 72-year-old man who sustained penetrating injury to the left eye with an agave plant presented to our clinic 16 months after the initial injury. Before presentation, the patient had developed endophthalmitis and had undergone anterior chamber washout, vitrectomy, and intravitreal steroids, antibiotics, antifungals, and anti–vascular endothelial growth factor therapy. At presentation, the patient had a blind, painful eye and subsequently underwent enucleation. Histopathology demonstrated granulomatous inflammation with multinucleated giant cells in the iris and Dalen–Fuchs nodules with CD68-positive epithelioid histiocytes associated with the retinal pigment epithelium sparing the choriocapillaris. These findings were initially attributed to sympathetic ophthalmia. The fellow eye did not have any signs of inflammation, and Grocott methenamine silver stain was positive for filamentous fungal elements, leading to a diagnosis of fungal endophthalmitis.

Conclusions:
Fungal endophthalmitis may develop histopathologic features that are similar to those observed in sympathetic ophthalmia. Recognition of the overlap between the histopathologic features of these diseases may reduce the possibility of misdiagnosis and unnecessary treatment of the fellow eye.
Inter‐habitat community variation of butterflies in an Afrotropical region
Authors: Onyenweaku Levi N. , Nwankwo Emmanuel C. , Ezealor Augustine U. 
Published: July 2023

AbstractThe impact of habitat disturbance on butterfly species assemblage in the Afrotropical region was studied by investigating inter‐habitat community variation of butterflies. Distinct butterfly species assemblages were found across surveyed habitat types, with 1554 adult butterflies of 126 species from five families recorded. The Primary forests had the highest species diversity and a higher dissimilarity between the Secondary and Plantation Forests. Of the 126 species recorded, 80 species were unique to one habitat. We provide new insights into butterfly ecology in the region, which can inform the development of conservation strategies to protect these ecosystems.
Sin, shame, and the subject
Authors: Jorgenson Allen G. 
Published: July 2023

AbstractIn this chapter I revisit construals of sin and shame, beginning with a moment of auto‐investigation. I then set this data in conversation with historical, theological, and philosophical configurations of shame to reconceive sin and shame. I describe sin as curvatus ex carne (turning from the flesh) to signal sin as a refusal of both our embodied existence and a commodification of the land on which it lives. I then use a carnal hermeneutic to argue for a positive understanding of discerning shame as a resource for an ethical life that contrasts with shame of disgrace.