bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of trypsin on biochemical and functional properties of decellularized porcine articular cartilage
Authors: Kirillova A. D. , Nemets E. A. , Grigoriev A. M. , Kirsanova L. A. , Ryzhikova V. A. , Volkova E. A. , Basok Yu. B. , Sevastianov V. I. 
Published: September 2023

Objective: to study the effect of trypsin pretreatment in the porcine articular cartilage decellularization protocol on the ability to restore the biochemical composition and functional properties of the resulting finely dispersed tissue-specific scaffold when co-cultured with human adipose-derived stem cells (hADSCs).Materials and methods. Porcine articular cartilage was micronized to a maximum size of 250 μm. The resulting porcine articular cartilage microparticles (CMps) were treated with trypsin (0.05, 0.25, 0.50%) / EDTA solution at +37 °C for 24 hours. Then, the CMps were successively incubated for 24 hours in three surfactant solutions containing 0.1% sodium dodecyl sulfate and increasing concentration of Triton X-100 (1, 2, 3%) at room temperature and in DNase I solution at +37 °C for 48 hours. The degree of change in the biochemical composition and the ability of decellularized CMps (DCMps) scaffolds within cell-engineered constructs (CECs) to support hADSC adhesion and proliferation, as well as their potential ability to exert a stimulatory regenerative effect, were then assessed. DNA, glycosaminoglycans (GAGs) and collagen content in the DCMps and CECs were examined. The morphology of the samples was examined using histological and immunohistochemistry staining.Results. Histological analysis showed that there were no cells and detritus in the DCMp samples. Pretreatment of CMps samples гыштп a solution with the lowest content of trypsin (0.05%) / EDTA in the samples retained 5.14 ± 0.87 ng/mg DNA in the samples, while GAG content decreased to 5.34 ± 0.9 μg/mg and collagen to 154 ± 34 μg/mg. By day 28 of CEC cultivation, adherent cells had produced their own extracellular matrix (ECM) containing GAGs and collagen. The amount of DNA in it was 6.30 ± 0.11 μg/CEC and that of GAGs was 19.36 ± 0.73 μg/CEC.Conclusion. Pretreatment with trypsin allows achieving uniformly complete decellularized CMps. At the same time, onset of changes in the ECM composition indicates a decrease in the ability of hADSCs to synthesize GAGs and type II collagen during co-culturing with DCMps. The increased proliferative activity of adherent hADSCs, as well as the tissue specificity of the DCMp scaffold will allow further research towards a hydrogel matrix capable of enhancing the specific and stimulating regenerative potential when co-cultured with cells of the same phenotype.
Paraurethral fibroadenoma of the vulva: a clinical case
Authors: Gvozdev M. Y. , Arefyeva A. O. , Prilepskaya E. A. , Lazareva E. K. , Dianov M. I. , Akhmedov A. K. 
Published: September 2023

Fibroadenoma of the vulva is a benign fibroepithelial tumor that is extremely rare. We present a rare clinical case of a 49-year-old woman with a large slow-growing paraurethral fibroadenoma of the vulva, confirmed by histological examination.This observation describes a rare pathology that contributed to urination disorders, which required surgical treatment and confirmation of the benign process by immunohistochemical examination.
Quantification of epicardial adipose tissue by computed tomographic scanning as a prognostic criterion of atrial fibrillation recurrence after catheter ablation
Authors: Golukhova E. Z. , Bulaeva N. I. , Alexandrova S. A. , Saparbaev A. A. , Abgaryan A. A. , Berdibekov B. Sh. 
Published: September 2023

Aim This study focused on a systematic review and meta-analysis on the predictive role of quantifying the epicardial adipose tissue (EAT) volume using data of computed tomography (CT) in patients after catheter ablation for atrial fibrillation (AF).Material and methods We performed a search in PubMed and Google Scholar for studies that examined the predictive value of EAT volume measured by CT for AF recurrence in patients after undergoing pulmonary venous isolation. Risk ratio (RR) values from studies, where similar scoring criteria were available, were pooled for the meta-analysis.Results Eighteen studies were selected from 901 publications for these systematic review and meta-analysis. In total, 4087 patients were included in this analysis (mean age, 59.0 years; mean follow-up duration, 14.9 mos). Patients with recurrent AF after ablation had higher left atrial EAT volume compared to patients without relapse (weighted mean difference, 5.99 ml; 95% CI: -10.04 to -1.94; p = 0.004). An increase in left atrial EAT volume per ml was significantly associated with the development of AF recurrence after ablation (RR 1.08; 95% CI: 1.01 to 1.16; p=0.03). Patients with recurrent AF after ablation also had higher total EAT values than patients without relapse (difference in weighted values, 11.67 ml; 95% CI: -19.81 to -3.54; p = 0.005). However, no significant association was found between the total EAT volume and the risk of AF relapse (RR 1.00; 95% CI: 1.00 to 1.01; p=0.06).Conclusions The volume of left atrial EAT measured by CT has a significant predictive value in AF patients after catheter ablation and can be used for stratification of the risk for recurrent AF.
The study of the mental characteristics of students with demonstrative character accentuation
Authors: Азарнов Н.Н. , Криушинская Г.В. 
Published: September 2023

Представлены результаты исследования психических особенностей студентов с демонстративной акцентуацией характера, проявляющиеся в учебной деятельности и общении с другими людьми. Уточнено определение акцентуации. Выделены основные виды акцентуаций характера личностей. Выявлены студенты с демонстративной акцентуацией характера. Обоснованы некоторые способы и приемы взаимодействия и общения с указанными лицами, способствующие снижению их акцентуации.
The results of the study of the mental characteristics of students with a demonstrative accentuation of character, manifested in educational activities and communication with other people, are presented. The definition of accentuation is clarified. The main types of character accentuations of personalities are highlighted. Students with demonstrative character accentuations were identified. Some methods and techniques of interaction and communication with these persons, contributing to the reduction of their accentuation, are substantiated.
THE ROLE OF OBSOLETE VOCABULARY IN THE LANGUAGE OF FICTION AND PECULIARITIES OF ITS TRA NSLATION
Authors: Безус С.Н. , Варфоломеева Н.С. 
Published: September 2023

Устаревшие слова (архаизмы и историзмы) представляют собой особый периферийный слой лексического состава языка. В художественных произведениях подобные лексемы выполняют различные функции: номинативную, изобразительную, информативную, когнитивную. В настоящей статье определяются роль архаизмов и историзмов в художественном произведении, а также выделяются различные их типы. При помощи описательного и сравнительно-сопоставительного методов уточняются способы перевода устаревшей лексики на примере исторической драмы современного испанского писателя Альфонсо Плоу «Король Санчо». Анализ перевода произведения позволил выявить такие приемы передачи устаревшей лексики на русский язык, как транслитерация, пояснение, трансформация (лексическая, грамматическая), опущение, дополнение.
Obsolete words (archaisms and historicisms) represent a special peripheral layer of the lexical composition of the language. In works of art, such lexemes perform various functions: nominative, pictorial, informative, cognitive. Th e paper defi nes the role of archaisms and historicisms in fi ction, as well as distinguishes their various types. Using descriptive and comparative methods, the authors clarify the ways of translating obsolete vocabulary by the example of the historical drama of the modern Spanish writer Alfonso Plow “King Sancho”. An analysis of the translation of the work made it possible to identify such methods of transferring obsolete vocabulary into Russian as transliteration, explanation, transformation (lexical, grammatical), omission, addition.
MECHANISMS OF INTERLINGUAL PARONYMY FORMATION IN GENETICALLY RELATED AND DIFFERENT LANGUAGES
Authors: Габдреева Н.В. , Лисина Г.М. , Гайнутдинова А.Ф. 
Published: September 2023

Выявляются особенности изменения и развития лексического состава разноструктурных языков. Специфика этого процесса рассмотрена на примере изучения межъязыковых коррелятивных пар. Выделяются семасиологические связи между прототипом (заимствованием) и коррелятом (лексемой в принимающем (русском) языке) в диахронно-синхронном соотношении. Рассмотрены примеры в русском литературном языке, а также в некоторых социальных диалектах (в молодежном сленге, криминальной лексике и лексике маргинальных слоев общества). Проанализирован ряд общих лингвистических процессов, имеющих место как в русском литературном языке, так и в русской субстандартной лексике, рассмотрены некоторые их отличия.
The article addresses an actual problem of modern linguistics – the identifi cation of the peculiarities of the change and development of the lexical composition of diff erent-structured languages by the example of the study of interlanguage correlative pairs. Th e semasiological relations between the prototype (a foreign word) and the correlate (the corresponding word in Russian) are considered in a diachronous-synchronous way. Examples are considered in the Russian literary language, as well as in some social dialects (youth slang, criminal vocabulary and the vocabulary of marginal strata of society). A number of general linguistic processes that take place both in the Russian literary language and in the Russian substandard vocabulary are analyzed, some of their diff erences are considered.
ТЕМПОРАЛЬНАЯ ХАРАКТЕРИСТИКА ЦЕННОСТЕЙ «ВЛАСТЬ» И «СПРАВЕДЛИВОСТЬ» НОСИТЕЛЕЙ РУССКОЙ КУЛЬТУРЫ
Authors: Ильина В.А. , Завьялова Ю.Н. 
Published: September 2023

Рассматривается темпоральная характеристика ценностей «власть» и «справедливость» с опорой на темпоральные шкалы, используемые в качестве инструмента анализа содержания ценностей в языковом сознании носителей русской культуры. Материалом исследования являются две базовые ценности, данные психосемантического эксперимента. Шкалирование применяется в качестве метода исследования. На основе полученных результатов эксперимента делается вывод о том, что при анализе темпоральной характеристики ценности «власть» максимальные значения выявлены по шкалам «долговременность» и «непрерывность»; максимальные значения по шкалам «долговременность» и «прерывность» были определены при анализе ценности «справедливость».
The article defi nes the temporal characteristics of power and justice as values based on temporal scales used as a tool for analyzing the values content in the linguistic consciousness of Russian culture representatives. Two basic values serve as the material for the psychosemantic experiment. Scaling is used as a research method. According to the research results, the temporal characteristic of power is based on the maximum parameters on the scales of long-term and continuous, the maximum parameters on the scales of long-term and discontinuous were determined as temporal characteristics of justice.
ORGANIZING STRA TEGY AS THE KEY COMMUNICATION STRA TEGY ON A CULINARY WEBSITE
Authors: Мухина И.К. , Липанина А.С. 
Published: September 2023

Анализируются разнообразные коммуникативные ситуации, в рамках которых взаимодействуют пользователи сайта «Поварёнок.ру», и языковые средства, их репрезентирующие. Наряду с другими, в качестве наиболее частотно применяемой пользователями выделяется организующая стратегия, которая выражается в этикетных ходах приветствия, обращения, прощания, выражения знаков внимания. Рассматривается реализация организующей коммуникативной стратегии в комплексных речевых жанрах: обсуждение, комментарий на кулинарном сайте. Выявлено, что синтактика данных жанров в качестве композиционных частей включает речевые акты обращения, одобрения, похвалы, пожелания чего-либо хорошего.
The article analyzes a variety of communicative situations in which users of the Povarenok. ru website interact, and the language means that represent them. Along with others, the organizing strategy is marked as the most frequently used by users, which is expressed in the etiquett e gestures of greeting, addressing, saying goodbye, expressing signs of att ention. Th e article considers the implementation of the organizing communicative strategy in the complex speech genres “Discussion”, “Commentary on a culinary website”. It is revealed that the syntactics of these genres includes speech acts of address, approval, praise, wishes for something good as compositional parts.
РЕЧЕВОЙ АКТ ПРИЗЫВА К СВЕРЖЕНИЮ ВЛАСТИ КАК ОБЪЕКТ ЛИНГВОЭКСПЕРТНОЙ ОЦЕНКИ
Authors: Янченкова И.С. 
Published: September 2023

Рассматриваются иллюстрации речевого акта призыва экстремистского содержания в русской речи. Описаны речевые средства репрезентации акта призыва, выявлены их функционально-семантические и коммуникативно-прагматические свойства, предложена процедура анализа речевого акта призыва экстремистского содержания. Материалы представляют практическую ценность для лингвистов, юристов, занимающихся вопросами лингвоэкспертной оценки материалов экстремистской направленности в русской речи, а также для студентов и аспирантов, изучающих лингвистику текста, филологический анализ текста, юрислингвистику, лингвистическую экспертизу.
The article focuses on the illustrations of the speech act with extremist content in Russian speech, describes the speech means of representation of the act of appeal, identifi es their functional-semantic and communicative-pragmatic properties, and proposes a procedure for analyzing the extremist speech act. The materials of the article are of practical value for linguists, lawyers dealing with the issues of linguistic expert evaluation of extremist materials in the Russian speech, as well as for students and postgraduates studying the linguistics of the text, philological analysis of the text, legal linguistics, linguistic expertise.
Determining Frequency Importance Function for Speech Intelligibility of Persian Monosyllabic Words and the List of Quick Speech in Noise in Persian Language
Authors: Taghavi Seyyed Mohammad Reza , Mohammadkhani Ghassem , Rouhbakhsh Nematollah , Taghavi Seyyed Ali Mohammad , Jalilvand Hamid , Fatahi Farzaneh 
Published: September 2023

Background and Aim: The Frequency Importance Function (FIF) is the main component of the Speech Intelligibility Index (SII) for a certain language. The FIF indicates the relative importance of each frequency band as it contributes to speech intelligibility. This study was conducted to determine the FIF for the Persian monosyllabic words and the list of Quick Speech in Noise (QSIN) in Persian language.
Methods: In this exploration study, 34 monolingual Persian-speaking subjects aged 25–40 years with normal hearing (17 males) were included. The FIF was evaluated for 100 monosyllabic words and 30 sentences of Persian QSIN under 180 different auditory conditions. The speech recognition scores were calculated and crossover frequencies were determined. Then, the relative transfer function was extracted and FIFs were calculated.
Results: The findings showed that for monosyllabic word material, the FIF had three peaks at 178, 1787, and 4467 Hz and for Persian QSIN, the FIF had an initial peak at about 141 Hz followed by a peak at about 1800 Hz. According to the results, the frequency range 891–8913 Hz is very important for recognition of the Persian words. Moreover, the mean crossover frequencies for the Persian sentences was 1446 Hz.
Conclusion: For monosyllabic word material in the Persian language, the FIF at 708–1778 Hz is very important for recognition of the Persian monosyllabic words. For sentence material in the Persian Language, the FIF at 708–4467 Hz has the highest importance for recognition of Persian sentences.
Keywords: Frequency importance function; speech intelligibility index; monosyllabic word; quick speech in noise list; Persian language
Combining Vestibular Rehabilitation and Noisy Galvanic Vestibular Stimulation for Treatment of Unilateral Vestibulopathy: A Randomized Controlled Trial
Authors: Khavarghazalani Bahare , Ghahraman Mansoureh Adel , Hoseinabadi Reza , Jalaie Shohreh , Kouhi Ali , Yazdani Nasrin 
Published: September 2023

Background and Aim: Vestibular Rehabilitation (VR) is a well-accepted treatment for Unilateral Vestibulopathy (UVP). Since noisy Galvanic Vestibular Stimulation (nGVS) improves the processing of vestibular inputs, we assessed the synergistic effects of adding nGVS to vestibular rehabilitation for the treatment of UVP.
Methods: Patients with UVP were randomly assigned into two groups receiving either VR for four weeks (VR group, n=12) or VR for four weeks combined with nGVS for three sessions (VR+nGVS group; n=12). Outcome measurements were postural control parameters measured with eyes open/closed conditions on hard/soft surfaces, Vestibulo-Ocular Reflex (VOR) gain, and Dizziness Handicap Inventory (DHI) scores that were assessed at baseline and after four weeks.
Results: All postural control parameters, mean total and subscale scores of DHI, and mean VOR gain in directions of affected canals significantly improved in both groups after interventions (p<0.05) except mean mediolateral displacement in conditions with eyes closed on hard surface and with eyes open on soft surface, mean mediolateral velocity in conditions with eyes closed on hard surface, ability to stance with eye closed condition on soft surface and mean emotional subscale of DHI in VR group. Improvements were significantly higher in postural control outcomes measured in stances with eyes closed on hard surface and with eyes open and closed on soft surface, mean VOR gains in directions of affected horizontal and anterior canals, and mean total, physical, and functional scores of DHI in VR+nGVS group (p<0.05).
Conclusion: When combined with VR, nGVS shows additional therapeutic effects in UVP patients.
Keywords: Unilateral peripheral vestibulopathy; vestibular compensation; galvanic vestibular stimulation; vestibular rehabilitation; postural control
Effect of Binaural Beat Stimulation on Auditory and Visual Sustained Attentions in Young People with Normal Hearing
Authors: Sabet Vida Khorsand , Mohammadkhani Ghassem , Rouhbakhsh Nematollah , Tavanai Elham 
Published: September 2023

Background and Aim: Numerous studies have investigated the effect of binaural beat stimulation on visual attention. In this study, we aim to investigate the effect of binaural beats on both auditory and visual sustained attention of young people with normal hearing.
Methods: Thirty normal-hearing people with mean age of 27.77±6.85 years were divided into two groups of Sham-Binaural beat (SB, n=15) and Binaural beat-Sham (BS, n=15). The participants in each group performed the Integrated Visual and Auditory-2 Continuous Performance Test (IVA-2 CPT) twice on different days. The SB group performed the IVA-2 CPT first under sham condition and then in the presence of binaural beats. In the BS group, the order was reversed in terms of stimuli presentation. The binaural beat stimulus was an audio file that induced beats at a frequency of 16 Hz by presenting 400 and 416 Hz stimuli to the right and left ears, respectively. The sham stimulus was a pure tone of 400 HZ. A mixed analysis of variance (ANOVA) was used to compare the means.
Results: The results showed the significant effect of binaural beat stimulation on auditory sustained attention (p<0.001). However, its effect on visual sustained attention was not significant (p=0.061).
Conclusion: Stimulation with binaural beats of 16 Hz may improve the auditory sustained attention in young people with normal hearing. It cannot improve their visual sustained attention.
Keywords: Binaural beat stimulation; visual; auditory; sustained attention
Effect of Different Blood Groups on Auditory Brainstem Response Findings
Authors: Kamalakannan Karupaiah , Sona Aronprabu Chrislin , Sivaranjani Sivagnanam , Thiriveni Surendran , Bhuvaneswari Kumaar , Prabhu Prashanth 
Published: September 2023

Background and Aim: The human blood group system can have an effect on the health and auditory system. The present study aimed to determine the differences in the Auditory Brainstem Response (ABR) recordings among persons with different blood groups (AB, A, B, O).
Methods: Sixty adults aged between 18 and 25 years with normal hearing sensitivity took part in the study. Further, they were grouped into four groups based on their blood groups (A, B, AB, O). Each group consisted of 15 participants. Auditory brainstem responses were recorded for all the participants at different rates (11.1/s and 90.1/s).
Results: The results of the study showed that the amplitude of ABR waves was significantly reduced for individuals with blood group O at lower repetition rate. The amplitude and latency of wave V was reduced at higher repetition rate among individuals with blood group O. There was no significant difference for all the other parameters across the groups.
Conclusion: The result of the study suggests the possibility of lesser auditory nerve functioning and increased risk of cochlear synaptopathy in persons with the O blood group.
Keywords: Auditory brainstem response; outer hair cell; auditory nerve; cochlear synaptopathy
Mortality Rate and Years of Life Lost Due to Road Traffic Accidents in Fars Province, 2004-2019
Authors: Azarbakhsh Habibollah , Rezaei Fatemeh , Dehghani Seyed Sina , Hassanzadeh Jafar , Dehghani Seyed Parsa , Mirahmadizadeh Alireza 
Published: September 2023

Background: Traffic accidents are one of the most critical health problems and the ninth leading cause of death globally. We aimed to determine the Mortality rate and the number of Years of Life Lost (YLL) due to road traffic accidents.
Methods: In this retrospective cohort study, mortality rate and YLL due to road traffic accidents were examined in Fars province, central Iran during the years 2004-2019. Mortality statistics were collected through death registration of ministry of health and medical education for Fars Province. Age Standardized mortality Rate (ASR) was calculated and join point regression analysis carried out to examine the trend of YLL rate. Data were analyzed using Excel spreadsheet version 2016 and Join point Regression Program 4.9.0.0.
Results: During the 16-year study period, 25,858 deaths due to road traffic accidents occurred in the province. 79.2% (20483 cases) were in men, and 33.7% (8703 cases) were aged 15-29 years. Total YLL during the 16-year study period were 458,975 (14.6 per 1000 people) in men, 117,999 (3.8 per 1000 people) in women. According to the join point regression, the 16- year trend of YLL rate due to premature mortality was decreasing: AAPC was -4.9% (95% CI: -8.8 to -0.9; P=0.018) for male, and -3.5% (95% CI: -6.3 to-0.5; P=0.011) for female.
Conclusion: Considering that the number of deaths, mortality rate and YLL has decreased in Fars province during the 16 years under study. Therefore, because the mortality rate due to road traffic accidents in Iran is higher than the global average, the need for training programs for drivers, compliance with standards and retrofitting of vehicles, road safety, driving supervision and the use of seat belts are essential.