bluuebunny/crossref_metadata_2025_split huggingface dataset:
Breaking Generational Curses: Success and Opportunity among Black Children of Incarcerated Parents
Authors: Gatewood Britany J , Muhammad Bahiyyah M , Turner Sydni 
Published: June 2023

Abstract
Black children are disproportionately represented among the children of incarcerated mothers and fathers in the United States. Research has largely focused on negative life outcomes (e.g., incarceration, negative behaviors, school dropout rates) of these children. Recently, studies have begun to look at success; however, children of incarcerated parents are typically placed into a homogenous group without considering racial implications. Using a critical race theoretical perspective, this study highlights the counternarrative of success by analyzing 59 in-depth interviews. Findings center on the ways adult Black children of incarcerated parents define success, which differs from middle-class, Eurocentric definitions of economic success, college graduation, marriage, and children as the success indicators. Success in relationships, community, education, and mental health emerged as the themes that define success. Findings show that their relationship with others (including their incarcerated parent), giving back to the community, educational experiences, and improving their mental health were indicators that they have “made it.” With support from their personal networks, they can succeed despite institutional and structural barriers. This study may assist policymakers, organizations, and schools with shifting societal perceptions to tailor resources for Black children of incarcerated parents to help invest in their futures.
Update on copper and selenium in Canadian cow–calf herds: regional differences and estimation of serum reference values
Authors: Waldner Cheryl , McLeod Lianne , Parker Sarah , Campbell John 
Published: June 2023

Abstract
Trace mineral supplementation of beef cattle is essential for efficient reproduction and herd health. Understanding regional differences in cow trace mineral status could inform decisions about risks of deficiencies and supplementation management. Cow–calf surveillance projects provided three opportunities to evaluate the trace mineral status of Canadian beef cow herds. Blood samples were collected at pregnancy testing in 2014 from 102 cow–calf herds and in 2016 from 86 cow–calf herds in Western Canada. In 2019, blood samples were collected at pregnancy testing from cows in 163 cow–calf herds from Eastern and Western Canada. Serum samples were analyzed for copper, selenium, and molybdenum concentrations using a plasma mass spectrometer. The prevalence of copper deficient cows sampled from the Western provinces ranged from 24% to 43% across the three periods, and was 20% from Eastern Canada in 2019. The prevalence of selenium deficient cows ranged from 0.2% to 0.4% across the three projects in Western Canada, but was higher in Eastern Canada at 4.6% in 2019. High serum molybdenum was identified in 9.4% to 14% of cows across the three periods in Western Canada and in 15% of cows sampled in Eastern Canada in 2019. Serum copper, selenium, and molybdenum concentrations varied by cow age and month of sample collection. Serum selenium and molybdenum concentrations, but not copper, varied by soil type associated with the location of the farm. A subsample of samples from cows from Western Canadian herds provided body condition score (BCS) data, pregnancy status, and calf survival data and were used to estimate updated serum reference values for adequate concentrations. Age-specific values were required for selenium and molybdenum. Reference intervals (80%) were estimated from 2,406 pregnant beef cows from 99 herds with each cow having a BCS ≥ 2.5/5 and a live calf at 3 wk with no retained placenta: copper for all cows (0.379 to 0.717 ppm), selenium for cows &lt;4 yr (0.052 to 0.152 ppm), and selenium for cows ≥4 yr (0.064 to 0.184 ppm). Upper 90% reference limits were also estimated for serum molybdenum for cows &lt;4 yr (&gt;0.104 ppm) and cows ≥4 yr (&gt;0.110 ppm). The lower limits for the reference intervals for adequate copper and selenium are below those previously reported; nevertheless, they represent a large sample that was specifically applicable to extensively managed beef animals in western Canada.
Risk Factors of Infectious Complications in Pediatric Patients With Cerebral Palsy After Spinal Arthrodesis
Authors: Miskiewicz Michael , Hidalgo Perea Sofia , Magruder Matthew , Abdelgawad Amr 
Published: June 2023

Study Design:
This was a retrospective study.

Objective:
The main objective of this study was to investigate (1) whether pediatric patients with cerebral palsy (CP) have higher rates of postoperative infectious complications after spinal fusion and (2) risk factors for postoperative infections.

Summary of Background Data:
Prior studies have shown that patients with CP undergo corrective spine surgery more often than the general population, yet typically have worse postoperative outcomes. Further investigation is needed to improve our understanding of the perioperative factors that place children with CP at greater risk of postoperative infectious complications.

Patients and Methods:
The 2019 “American College of Surgeons National Surgical Quality Improvement Program” Pediatric database was used for patient data. The univariable analysis compared the prevalence of preoperative comorbidities and perioperative factors between children with and without CP. Multivariable logistic regression modeling was used to ascertain independent risk factors for postoperative infectious complications.

Results:
A total of 4445 patients were included in the study; 606 (13.63%) patients had CP and 3839 (86.37%) did not. Patients with CP were more likely to have several notable preoperative comorbidities, and the rate of developing any infectious complication was more than 7 times greater in the CP cohort than in the control cohort (14.36% vs 1.88%; P<0.001). Multivariable analysis revealed CP [odds ratio (OR): 3.55, CI: 2.25–5.60; P<0.001], American Society of Anesthesiologists class 3 or higher (OR: 2.10, CI: 1.29–3.42; P = 0.003), and hematologic disorders (OR: 2.01, CI: 1.06–3.83; P = 0.033) to be independent risk factors for increased postoperative infectious complications.

Conclusions:
CP is an independent risk factor for the development of 30-day postoperative infectious complications in pediatric patients. In addition, the American Society of Anesthesiologists class 3 or higher and hematologic disorders were risk factors for postoperative infections after spinal fusion surgery.
Decreasing the Pedicle Screw Misplacement Rate in the Thoracic Spine With Robot-guided Navigation
Authors: Vardiman Arnold B. , Wallace David J. , Booher Grant A. , Toossi Nader , Bucklen Brandon S. 
Published: June 2023

Study Design:
A retrospective chart review.

Objective:
The aim of this study was to evaluate the screw accuracy of thoracic pedicle screws placed with a robot-guided navigation system.

Summary of Background Data:
Thoracic pedicles are smaller in diameter than lumbar pedicles, making pedicle screw placement difficult. Misplaced pedicle screws may present complications including decreased construct stability, and increased risks of neurological deficits and blood vessel perforation. There is a dearth of knowledge on thoracic pedicle screw accuracy placed with a robot.

Materials and Methods:
A retrospective analysis of the robot-assisted placement of thoracic pedicle screws was performed. Preoperative and postoperative computed tomography (CT) scans of the implanted thoracic screws were collected to assess screw placement accuracy, pedicle breadth, and placement deviations. A CT-based Gertzbein and Robbins System was used to classify pedicle screw accuracy in 2 mm increments. A custom image overlay software was used to determine the deviations between the preoperatively planned trajectory of pedicle screws and final placement at screw entry (tail), and tip in addition to the angular deviation.

Results:
Seventy-five thoracic pedicle screws were implanted by navigated robotic guidance in 17 patients, only 1.3% (1/75) were repositioned intraoperatively. Average patient age and body mass index were 57.5 years and 25.9 kg/m2, respectively, with 52.9% female patients. Surgery diagnoses were degenerative disk disease (47.1%) and adjacent segment disease (17.6%). There were zero complications, with no returns to the operating room. According to the CT-based Gertzbein and Robbins pedicle screw breach classification system, 93.3% (70/75) screws were grade A or B, 6.6% (5/75) were grade C, and 0% were grade D or E. The average deviation from the preoperative plan to actual final placement was 1.8±1.3 mm for the screw tip, 1.6±0.9 mm for the tail, and 2.1±1.5 degrees of angulation.

Conclusions:
The current investigation found a 93.3% accuracy of pedicle screw placement in the thoracic spine. Navigated robot assistance is a useful system for placing screws in the smaller pedicles of the thoracic spine.

Level of Evidence:
Level III—retrospective nonexperimental study.
A Closed-system Technology for Mechanical Isolation of High Quantities of Stromal Vascular Fraction from Fat for Immediate Clinical Use
Authors: Solodeev Inna , Meilik Benjamin , Gur Eyal , Shani Nir 
Published: June 2023

Background:
Adipose tissue stromal vascular fraction (SVF) is increasingly used in the clinic. SVF separation from fat by enzymatic disruption is currently the gold standard for SVF isolation. However, enzymatic SVF isolation is time-consuming (~1.5 h), costly and significantly increases the regulatory burden of SVF isolation. Mechanical fat disruption is rapid, cheaper, and less regulatory challenging. However, its reported efficacy is insufficient for clinical use. The current study evaluated the efficacy of a novel rotating blades (RBs) mechanical SVF isolation system.

Methods:
SVF cells were isolated from the same lipoaspirate sample (n = 30) by enzymatic isolation, massive shaking (wash), or engine-induced RBs mechanical isolation. SVF cells were counted, characterized by flow cytometry and by their ability to form adipose-derived stromal cells (ASCs).

Results:
The RBs mechanical approach yielded 2 × 105 SVF nucleated cells/mL fat, inferior to enzymatic isolation (4.17 × 105) but superior to cells isolating from fat by the “wash” technique (0.67 × 105). Importantly, RBs SVF isolation yield was similar to reported yields achieved via clinical-grade enzymatic SVF isolation. RBs-isolated SVF cells were found to contain 22.7% CD45-CD31−CD34+ stem cell progenitor cells (n = 5) yielding quantities of multipotent ASCs similar to enzymatic controls.

Conclusions:
The RBs isolation technology provided for rapid (<15 min) isolation of high-quality SVF cells in quantities similar to those obtained by enzymatic digestion. Based on the RBs platform, a closed-system medical device for SVF extraction in a rapid, simple, safe, sterile, reproducible, and cost-effective manner was designed.
2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension
Authors: Mancia Giuseppe , Kreutz Reinhold , Brunström Mattias , Burnier Michel , Grassi Guido , Januszewicz Andrzej , Muiesan Maria Lorenza , Tsioufis Konstantinos , Agabiti-Rosei Enrico , Algharably Engi Abd Elhady , Azizi Michel , Benetos Athanase , Borghi Claudio , Hitij Jana Brguljan , Cifkova Renata , Coca Antonio , Cornelissen Veronique , Cruickshank J. Kennedy , Cunha Pedro G. , Danser A.H. Jan , Pinho Rosa Maria de , Delles Christian , Dominiczak Anna F. , Dorobantu Maria , Doumas Michalis , Fernández-Alfonso María S. , Halimi Jean-Michel , Járai Zoltán , Jelaković Bojan , Jordan Jens , Kuznetsova Tatiana , Laurent Stephane , Lovic Dragan , Lurbe Empar , Mahfoud Felix , Manolis Athanasios , Miglinas Marius , Narkiewicz Krzystof , Niiranen Teemu , Palatini Paolo , Parati Gianfranco , Pathak Atul , Persu Alexandre , Polonia Jorge , Redon Josep , Sarafidis Pantelis , Schmieder Roland , Spronck Bart , Stabouli Stella , Stergiou George , Taddei Stefano , Thomopoulos Costas , Tomaszewski Maciej , Van de Borne Philippe , Wanner Christoph , Weber Thomas , Williams Bryan , Zhang Zhen-Yu , Kjeldsen Sverre E. 
Published: June 2023

Document Reviewers:Luis Alcocer (Mexico), Christina Antza (Greece), Mustafa Arici (Turkey), Eduardo Barbosa (Brazil), Adel Berbari (Lebanon), Luís Bronze (Portugal), John Chalmers (Australia), Tine De Backer (Belgium), Alejandro de la Sierra (Spain), Kyriakos Dimitriadis (Greece), Dorota Drozdz (Poland), Béatrice Duly-Bouhanick (France), Brent M. Egan (USA), Serap Erdine (Turkey), Claudio Ferri (Italy), Slavomira Filipova (Slovak Republic), Anthony Heagerty (UK), Michael Hecht Olsen (Denmark), Dagmara Hering (Poland), Sang Hyun Ihm (South Korea), Uday Jadhav (India), Manolis Kallistratos (Greece), Kazuomi Kario (Japan), Vasilios Kotsis (Greece), Adi Leiba (Israel), Patricio López-Jaramillo (Colombia), Hans-Peter Marti (Norway), Terry McCormack (UK), Paolo Mulatero (Italy), Dike B. Ojji (Nigeria), Sungha Park (South Korea), Priit Pauklin (Estonia), Sabine Perl (Austria), Arman Postadzhian (Bulgaria), Aleksander Prejbisz (Poland), Venkata Ram (India), Ramiro Sanchez (Argentina), Markus Schlaich (Australia), Alta Schutte (Australia), Cristina Sierra (Spain), Sekib Sokolovic (Bosnia and Herzegovina), Jonas Spaak (Sweden), Dimitrios Terentes-Printzios (Greece), Bruno Trimarco (Italy), Thomas Unger (The Netherlands), Bert-Jan van den Born (The Netherlands), Anna Vachulova (Slovak Republic), Agostino Virdis (Italy), Jiguang Wang (China), Ulrich Wenzel (Germany), Paul Whelton (USA), Jiri Widimsky (Czech Republic), Jacek Wolf (Poland), Grégoire Wuerzner (Switzerland), Eugene Yang (USA), Yuqing Zhang (China).
Prediction of early functional outcomes in patients after robotic-assisted total knee arthroplasty: a nomogram prediction model
Authors: Duan Xudong , Zhao Yiwei , Zhang Jiewen , Kong Ning , Cao Ruomu , Guan Huanshuai , Li Yiyang , Wang Kunzheng , Yang Pei , Tian Run 
Published: June 2023

Background:
Robotic-assisted total knee arthroplasty (RA-TKA) is becoming more and more popular as a treatment option for advanced knee diseases due to its potential to reduce operator-induced errors. However, the development of accurate prediction models for postoperative outcomes is challenging. This study aimed to develop a nomogram model to predict the likelihood of achieving a beneficial functional outcome. The beneficial outcome is defined as a postoperative improvement of the functional Knee Society Score (fKSS) of more than 10 points, three months after RA-TKA by early collection and analysis of possible predictors.

Methods:
This is a retrospective study on 171 patients who underwent unilateral RA-TKA at our hospital. The collected data included demographic information, preoperative imaging data, surgical data, and preoperative and postoperative scale scores. Participants were randomly divided into a training set (N=120) and a test set (N=51). Univariate and multivariate logistic regression analyses were employed to screen for relevant factors. Variance Inflation Factor (VIF) was used to investigate for variable collinearity. The accuracy and stability of the models were evaluated using calibration curves with the Hosmer-Lemeshow goodness-of-fit test, consistency index (C-index) and receiver operating characteristic (ROC) curves.

Results:
Predictors of the nomogram included preoperative Hip-Knee-Ankle (HKA) angle deviation, preoperative 10-cm visual analogue scale (VAS) score, preoperative fKSS score and preoperative range of motion (ROM). Collinearity analysis with demonstrated no collinearity among the variables. The C-index values for the training and test sets were 0.908 and 0.902, respectively. Finally, the area under the ROC curve was 0.908 (95% CI 0.846-0.971) in the training set and 0.902 (95% CI 0.806-0.998) in the test set.

Conclusion:
A nomogram model was designed hereby aiming to predict the functional outcome three months after RA-TKA in patients. Rigorous validation showed that the model is robust and reliable. The identified key predictors include preoperative HKA angle deviation, preoperative VAS score, preoperative fKSS score, and preoperative ROM. These findings have major implications for improving therapeutic interventions and informing clinical decision-making in patients undergoing RA-TKA.
Effect of laparoscopic sleeve gastrectomy on mobilization of site-specific body adipose depots: a prospective cohort study
Authors: Cui Beibei , Duan Junhong , Zhu Liyong , Wang Guohui , Sun Xulong , Su Zhihong , Liao Yunjie , Yi Bo , Li Pengzhou , Li Weizheng , Song Zhi , Li Zheng , Tang Haibo , Rong Pengfei , Zhu Shaihong 
Published: June 2023

Background:
Effect of bariatric surgery on mobilization of site-specific body adipose depots is not well investigated. Herein, we conducted a prospective cohort study to assess whether bariatric surgery can differentially affect specific fat storage pools and to further investigate correlations between site-specific fat mobilization and clinical outcomes.

Materials and Methods:
In this single-center prospective cohort study, 49 participants underwent laparoscopic sleeve gastrectomy (LSG) from 24 May 2022 to 20 October 2022 and underwent magnetic resonance imaging to estimate subcutaneous fat area (SFA), visceral fat area (VFA), hepatic and pancreatic proton density fat fraction (PDFF) at baseline and 3 months after surgery. The protocol for this study was registered on clinicaltrials.gov.

Results:
Among 49 patients who met all inclusion criteria, the median (interquartile range [IQR]) age was 31.0 (23.0–37.0) years, the median (IQR) body mass index was 38.1 (33.7–42.2) kg/m2 and 36.7% were male. Median (IQR) percentage hepatic PDFF loss was the greatest after bariatric surgery at 68.8% (47.3%–79.7%), followed by percentage pancreatic PDFF loss at 51.2% (37.0%–62.1%), percentage VFA loss at 36.0% (30.0%–42.4%), and percentage SFA loss at 22.7% (17.2%–32.4%) (P<0.001). By calculating Pearson correlation coefficient and partial correlation coefficient, the positive correlations were confirmed between change in VFA and change in glycated hemoglobin (r=0.394, P=0.028; partial r=0.428, P=0.042) and between change in hepatic PDFF and change in homeostatic model assessment of insulin resistance (r=0.385, P=0.025; partial r=0.403, P=0.046).

Conclusions:
LSG preferentially mobilized hepatic fat, followed by pancreatic fat and visceral adipose tissue (VAT), while subcutaneous adipose tissue was mobilized to the least extent. Reduction in VAT and hepatic fat is independently associated with the improvement of glucose metabolism after LSG.
A Comprehensive Program to Improve Treatment of Precancerous Cervical Lesions in the Rio Grande Valley of Texas
Authors: Varon Melissa , Salcedo Mila Pontremoli , Fellman Bryan , Troisi Catherine , Gowen Rose , Daheri Maria , Rodriguez Ana M. , Toscano Paul , Guerra Laura , Gasca Monica , Cavazos Blanca , Marin Elena , Fisher-Hoch Susan , Fernandez Maria E. , Reininger Belinda , Ruosha Li , Baker Ellen , Schmeler Kathleen 
Published: June 2023

Objective:
To assess the impact of a multicomponent intervention in women with cervical dysplasia who were treated with loop electrosurgical excision procedure (LEEP), as well as the time between colposcopy and treatment.

Design:
Retrospective cohort study.

Intervention:
Clinic participation in a multicomponent cervical cancer prevention program that included community outreach, patient in-reach, and navigation, as well as provider capacity building with in-person training and ongoing telementoring through Project ECHO.

Main Outcome Measures:
Medical records were reviewed to evaluate women with cervical dysplasia undergoing treatment with LEEP within 90 days of colposcopy, as well as time between colposcopy and treatment. Baseline data from year 1 were compared with each subsequent year of implementation. Additional variables examined included patient's age, history of abnormal screening results, and percentage of families living below poverty line based on county of residence, parity, and clinic site. We performed logistic regression and multiple linear regression analyses to assess the programmatic impact in the outcomes of interest by year of program implementation.

Results:
A total of 290 women were included in the study. The proportion of women undergoing treatment within 90 days of colposcopy increased from 76.2% at baseline to 91.3% in year 3 and 92.9% in year 4 of program implementation. The odds of undergoing treatment within 90 days were 5.11 times higher in year 4 of program implementation than at baseline. The mean time between colposcopy and LEEP decreased from 62 days at baseline to 45 days by year 4 of program implementation.

Conclusions:
Implementation of our multicomponent cervical cancer prevention program increased the proportion of women undergoing LEEP within 90 days of colposcopy and decreased the time between colposcopy and LEEP. This program has the potential to support cervical cancer prevention efforts and could be implemented in other low-resource settings.
Anticoagulation in emergency general surgery: Who bleeds more? The EAST multicenter trials ACES study
Authors: O’Meara Lindsay , Zhang Ashling , Baum Jeffrey N. , Cooper Amanda , Decker Cassandra , Schroeppel Thomas , Cai Jenny , Cullinane Daniel C. , Catalano Richard D. , Bugaev Nikolay , LeClair Madison J. , Feather Cristina , McBride Katherine , Sams Valerie , Leung Pak Shan , Olafson Samantha , Callahan Devon S. , Posluszny Joseph , Moradian Simon , Estroff Jordan , Hochman Beth , Coleman Natasha L. , Goldenberg-Sandau Anna , Nahmias Jeffry , Rosenbaum Kathryn , Pasley Jason D. , Boll Lindsay , Hustad Leah , Reynolds Jessica , Truitt Michael , Vesselinov Roumen , Ghneim Mira 
Published: June 2023

BACKGROUND
While direct oral anticoagulant (DOAC) use is increasing in the Emergency General Surgery (EGS) patient population, our understanding of their bleeding risk in the acute setting remains limited. Therefore, the objective of this study was to determine the prevalence of perioperative bleeding complications in patients using DOACs versus warfarin and AP therapy requiring urgent/emergent EGS procedures (EGSPs).

METHODS
This was a prospective observational trial, conducted between 2019 and 2022, across 21 centers. Inclusion criteria were 18 years or older, DOAC, warfarin/AP use within 24 hours of requiring an urgent/emergent EGSP. Demographics, preoperative, intraoperative, and postoperative data were collected. ANOVA, χ2, and multivariable regression models were used to conduct the analysis.

RESULTS
Of the 413 patients enrolled in the study, 261 (63%) reported warfarin/AP use and 152 (37%) reported DOAC use. Appendicitis and cholecystitis were the most frequent indication for operative intervention in the warfarin/AP group (43.4% vs. 25%, p = 0.001). Small bowel obstruction/abdominal wall hernias were the main indication for operative intervention in the DOAC group (44.7% vs. 23.8%, p = 0.001). Intraoperative, postoperative, and perioperative bleeding complications and in-hospital mortality were similar between the two groups. After adjusting for confounders, a history of chemotherapy (odds ratio [OR], 4.3; p = 0.015) and indication for operative intervention including occlusive mesenteric ischemia (OR, 4.27; p = 0.016), nonocclusive mesenteric ischemia (OR, 3.13; p = 0.001), and diverticulitis (OR, 3.72; p = 0.019) were associated with increased perioperative bleeding complications. The need for an intraoperative transfusion (OR, 4.87; p < 0.001), and intraoperative vasopressors (OR, 4.35; p = 0.003) were associated with increased in-hospital mortality.

CONCLUSION
Perioperative bleeding complications and mortality are impacted by the indication for EGSPs and patient's severity of illness rather than a history of DOAC or warfarin/AP use. Therefore, perioperative management should be guided by patient physiology and indication for surgery rather than the concern for recent antiplatelet or anticoagulant use.

LEVEL OF EVIDENCE
Prognostic and Epidemiologic; Level III.