bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of contamination with diesel oil on water sorptivity and hydrophobicity of sandy loam soil
Authors: Hewelke Edyta , Weber Jerzy , Gozdowski Dariusz , Hewelke Piotr 
Published: February 2023

AbstractThis paper shows the changes in water sorptivity (Sw) and hydrophobicity following soil contamination with petroleum hydrocarbons (PHs) under different soil moistures. Laboratory experiments were carried out to verify that contamination with PHs reduces Sw, thus affecting the infiltrability, which in practice influences the field water capacity and the availability of water for plants. Soil water repellency (SWR) was estimated by the repellency index (R) and water drop penetration time (WDPT). The increase in PHs contamination contributed to SWR and caused a significant decrease in Sw. With the decrease in moisture, the water sorptivity of the soil increased, reaching its maximum at 0.12–0.15 cm3 cm−3, which was the threshold value in the case of the analysed soil, and then decreased drastically. The R index and the WDPT revealed a similar trend, inversely related to the level of soil contamination with PHs. The increase in SWR and the accompanying decrease in Sw made the soil less resistant to drought. The total amount of water available to plants in the control soil was 19.04%, whereas contamination with PHs equal to 100 g kg−1 caused a decrease to 6.36%. The almost threefold decrease in the total amount of water has a fundamental influence on increasing the risk of soil drought. The results obtained indicated that the interrelationship presented between the level of contamination with PHs, water sorptivity, SWR and soil moisture are the keys to predicting the environmental effects of contamination with PHs. The obtained results indicate that the undertaken remediation measures aimed at restoring the hydrological function of the soil system should be preceded by an assessment of soil hydrophobicity.
LipR functions as an intracellular pH regulator in Bacillus thuringiensis under glucose conditions
Authors: Cai Xia , Qin Jiaxin , Li Xuelian , Yuan Taoxiong , Yan Bing , Cai Jun 
Published: February 2023

AbstractIntracellular pH critically affects various biological processes, and an appropriate cytoplasmic pH is essential for ensuring bacterial growth. Glucose is the preferred carbon source for most heterotrophs; however, excess glucose often causes the accumulation of acidic metabolites, lowering the intracellular pH and inhibiting bacterial growth. Bacillus thuringiensis can effectively cope with glucose‐induced stress; unfortunately, little is known about the regulators involved in this process. Here, we document that the target of the dual‐function sRNA YhfH, the lipR gene, encodes a LacI‐family transcription factor LipR as an intracellular pH regulator when B. thuringiensis BMB171 is suddenly exposed to glucose. Under glucose conditions, lipR deletion leads to early growth arrest by causing a rapid decrease in intracellular pH (~5.4). Then, the direct targets and a binding motif (GAWAWCRWTWTCAT) of LipR were identified based on the electrophoretic mobility shift assay, the DNase‐I footprinting assay, and RNA sequencing, and the gapN gene encoding a key enzyme in glycolysis was directly inhibited by LipR. Furthermore, Ni2+ is considered a possible effector for LipR. In addition to YhfH, the lipR expression was coregulated by itself, CcpA, and AbrB. Our study reveals that LipR plays a balancing role between glucose metabolism and intracellular pH in B. thuringiensis subjected to glucose stress.
Sobaity Seabream Culture in High-Temperature Conditions
Authors: Young Benjamin C. , Shaikhi Ali Al 
Published: February 2023

Abstract
The survival, growth performance, feed intake, and feed conversion ratio of cultured Sobaity Seabream Sparidentex hasta in local high temperatures of 24, 28, and 32°C were estimated in this study. Experiments were conducted in triplicates with 40 fish (99 g average body weight; 17 cm average total length) in each indoor 1-metric-ton fiber-reinforced plastic tank. For 96 d, the fish were fed a commercial diet (6-mm pellets, 46.36% crude protein, and 12.54% crude lipid). The results showed that survival and growth performance of juvenile Sobaity Seabream were affected by temperature. Total weight gain was significantly higher in the 32°C group (158.57 g), followed by the 28°C group (138.25 g), and the lowest weight gain was observed in the 24°C group (116.98 g). The feed conversion ratio (1.62) was significantly lower in the 32°C group than in the 28°C (1.8) and 24°C (1.85) groups. Feed intake was significantly higher in the 32°C and 28°C groups (6.20–6.43 g) than in the 24°C group (5.41 g). In the 32°C group, the survival rate was significantly lower. The condition factor showed no significant difference among the three temperatures. Overall, Sobaity Seabream farming is feasible at temperatures ranging from 24°C to 32°C.
Flexible-Pass-Through Antennas for Half-Duplex Passive Integrated Transponder Tags in Medium to Large Rivers Used to Study Size-Selective Reservoir Passage
Authors: Ohms Haley A. , Tranquilli J. Vincent , Brooks Gabriel , Boughton David A. 
Published: February 2023

Abstract
The use of passive integrated transponder (PIT) tags for studying fish behavior and demography in medium-large rivers is hindered by antenna designs that are susceptible to damage in those environments and low detection efficiencies. We designed a vertically oriented, flexible PIT tag antenna for half-duplex tags that is simple to construct and deploy, resilient to the dynamic river environment, retains the higher detection efficiency of pass-through antennas, and is suitable for rivers up to 30 m wide and 1.5 m deep. These “flexible-pass-through antennas” are economical to build and cost ~US$435 to $680 for a one- or two-winding antenna, respectively. We used two flexible-pass-through antennas to test for size-selective reservoir passage in juvenile steelhead Oncorhynchus mykiss (anadromous Rainbow Trout) and Rainbow Trout. We found that flexible-pass-through antennas withstood high flows and debris during a spring out-migration season and provided data to reject the hypothesis of size-selective fish passage at the Los Padres Dam and Reservoir on the Carmel River (California, USA).
3D printed peripheral vascular stents based on degradable poly(trimethylene carbonate‐b‐(L‐lactide‐ran‐glycolide)) terpolymer
Authors: Ni Na , Fan Tiantang , Ye Wuyou , Xia Qi , Liu Dongyang , Qin Jingwen , Fan Zhongyong , Liu Qing 
Published: February 2023

AbstractPoly(L‐lactic acid) (PLLA) is a biocompatible material and has found its application in bioresorbable vascular stents (BVS). However, the crystallization of pure PLLA makes it brittle as a medical implant device. In this work, the biodegradable poly(1,3‐trimethylene carbonate‐b‐(L‐lactide‐ran‐glycolide acid)) (PTLG) terpolymers with improved mechanical performance were developed and processed into peripheral vascular stents by a novel 3D 4‐axial printing technology. The PTLG terpolymers were successfully synthesized by ring‐opening copolymerization of L‐lactic acid (LLA), 1,3‐trimethylene carbonate (PTMC) and glycolide acid (GA) units. The crystallinity and mechanical properties of the PTLG terpolymers with various degradation rate depends on the chain sequence structure and the component contents. Compared with the stent prepared by laser engraving, the peripheral vascular stent prepared by the 3D 4‐axial printing technology exhibit a finer structure and smoother strut surface. It was found that both the strut diameters and the molecular weight of PTMC affect the radial force of the stents and that the apparent activation energy of thermal decomposition of the stents is mainly influenced by the molecular weight of PTMC and the component ratio. Therefore, the addition of the PTMC segment can effectively improve the flexibility of the PTLG terpolymer stent and the 3D printed PTLG terpolymer‐based stent. Furthermore, CCK‐8 and live/dead staining suggested that the stents have good biocompatibility.
Pain mitigation and management strategies for anti‐GD2 infusions: An expert consensus
Authors: Nysom Karsten , Morad Andrea Gomez , Rafael Margarida Simão , Zier Judith , Marachelian Araz , Watt Tanya , Morgenstern Daniel A. 
Published: February 2023

AbstractMonoclonal antibodies (mAbs) targeting disialoganglioside 2 (GD2) are an important treatment advance for high‐risk neuroblastoma, including in patients with refractory or relapsed disease. Dinutuximab and dinutuximab beta are administered for ≥8 hours (and up to 10 days for dinutuximab beta), whereas naxitamab is administered over 0.5 to 2 hours as tolerated. As acute pain is a class effect of anti‐GD2 mAbs, effective pain management is crucial to successful treatment. Here, we provide an overview of current pain‐management strategies for anti‐GD2 mAb infusions, with a focus on strategies suitable for naxitamab infusions, which cause a more rapid onset of often severe pain. We discuss opioid analgesics, ketamine, gabapentin, and other similar agents and nonpharmacologic approaches. Potential future pain‐management options are also discussed, in addition to the use of sedatives to reduce the anxiety that may be associated with infusion‐related pain. In this expert consensus paper, specific guidance for pain management during naxitamab infusions is provided, as these infusions are administered over 0.5 to 2 hours and may not need overnight hospitalization based on the physician's assessment, and require rapid‐onset analgesia options suitable for potential outpatient administration.
Novel and replicated clinical and genetic risk factors for toxicity from high‐dose methotrexate in pediatric acute lymphoblastic leukemia
Authors: Zobeck Mark , Bernhardt M. Brooke , Kamdar Kala Y. , Rabin Karen R. , Lupo Philip J. , Scheurer Michael E. 
Published: February 2023

AbstractStudy ObjectiveMethotrexate (MTX) is a key component of treatment for high‐risk pediatric acute lymphoblastic leukemia (ALL) but may cause acute kidney injury and prolonged hospitalization due to delayed clearance. The purpose of this study is to identify clinical and genetic factors that may predict which children are at risk for creatinine increase and prolonged MTX clearance.DesignWe conducted a single‐center, retrospective cohort study of pediatric patients with ALL who received 4000–5000 mg/m2 of MTX. Measurements We performed germline genotyping to determine genetic ancestry and allele status for 49 single nucleotide polymorphisms (SNPs) identified from the literature as related to MTX disposition. Bayesian hierarchical ordinal regression models for creatinine increase and for prolonged MTX clearance were developed.Main ResultsHispanic ethnicity, body mass index (BMI) < 3%, BMI between 85%–95%, and Native American genetic ancestry were found to be associated with an increased risk for creatinine elevation. Older age, Black race, and use of the intensive monitoring protocol were associated with a decreased risk for creatinine elevation. Older age, B‐ compared to T‐ALL, and the minor alleles of rs2838958/SLC19A1 and rs7317112/ABCC4 were associated with an increased risk for delayed clearance. Black race, MTX dose reduction, and the minor allele of rs2306283/SLCO1B1 were found to be associated with a decreased risk for delayed clearance.ConclusionsThese predictors of MTX toxicities may allow for more precise individualized toxicity risk prediction.
Proteomic identification of intracellular vesicle trafficking and protein glycosylation requirements for lumen inflation in Ciona notochord
Authors: Wang Zhuqing , Tan Zicheng , Bi Jianqing , Liu Amei , Jiang An , Dong Bo 
Published: February 2023

AbstractLumen formation and inflation are crucial steps for tubular organ morphogenesis, yet the underling mechanism remains largely unrevealed. Here, we applied 4D proteomics to screen the lumenogenesis‐related proteins and revealed the biological pathways potentially that are involved in lumen inflation during notochord lumen formation in the ascidian Ciona savignyi. In total, 910 differentiated expressed proteins (DEPs) were identified before and after notochord lumen formation utilizing Mfuzz analysis. Those DEPs were grouped into four upregulated clusters based on their quantitative expression patterns; the functions of these proteins were enriched in protein metabolic and biosynthetic process, the establishment of localization, and vesicle‐mediated transport. We analyzed the vesicle trafficking cluster and focused on several vesicle transport hub proteins. In vivo function‐deficient experiments showed that mutation of vesicle transport proteins resulted in an abnormal lumen in notochord development, demonstrating the crucial role of intracellular trafficking for lumen formation. Moreover, abundant extracellular matrix proteins were identified, the majority of which were predicted to be glycosylated proteins. Inhibition of glycosylation markedly reduced the lumen expansion rate in notochord cells, suggesting that protein glycosylation is essential for lumenogenesis. Overall, our study provides an invaluable resource and reveals the crucial mechanisms in lumen formation and expansion.
Adhesion improvement on the inner side of LLDPE/PA tubular film exposed to DCSBD roll‐to‐roll plasma system from the outer side of the film
Authors: Štěpánová Vlasta , Šrámková Petra , Sihelník Slavomír , Zemánek Miroslav , Jurmanová Jana , Stupavská Monika , Kováčik Dušan 
Published: February 2023

AbstractDiffuse coplanar surface barrier discharge (DCSBD) was used to activate the opposite side of the plasma‐exposed linear low‐density polyethylene/polyamide (LLDPE/PA) tubular film of multilayer casing. We determined that conductive metal rubber roller in the DCSBD system allowed the formation of microfilaments perpendicular to the film surface, resulting in improved wettability and adhesion of inner LLDPE side of the tubular film. These findings were supported by increasing the concentration of polar functional groups. Based on these remarkable outcomes obtained after a very short plasma exposure time of 0.5 s, DCSBD roll‐to‐roll system in proper arrangement affords adhesion improvement of the opposite side of the treated film without any material damage, hence can compete with industrial corona in commercial sphere of plasma treatments.
Genetically encoded non‐canonical amino acids reveal asynchronous dark reversion of chromophore, backbone, and side‐chains in EL222
Authors: Chaudhari Aditya S. , Chatterjee Aditi , Domingos Catarina A. O. , Andrikopoulos Prokopis C. , Liu Yingliang , Andersson Inger , Schneider Bohdan , Lórenz‐Fonfría Víctor A. , Fuertes Gustavo 
Published: February 2023

AbstractPhotoreceptors containing the light‐oxygen‐voltage (LOV) domain elicit biological responses upon excitation of their flavin mononucleotide (FMN) chromophore by blue light. The mechanism and kinetics of dark‐state recovery are not well understood. Here we incorporated the non‐canonical amino acid p‐cyanophenylalanine (CNF) by genetic code expansion technology at 45 positions of the bacterial transcription factor EL222. Screening of light‐induced changes in infrared (IR) absorption frequency, electric field and hydration of the nitrile groups identified residues CNF31 and CNF35 as reporters of monomer/oligomer and caged/decaged equilibria, respectively. Time‐resolved multi‐probe UV/visible and IR spectroscopy experiments of the lit‐to‐dark transition revealed four dynamical events. Predominantly, rearrangements around the A'α helix interface (CNF31 and CNF35) precede FMN‐cysteinyl adduct scission, folding of α‐helices (amide bands), and relaxation of residue CNF151. This study illustrates the importance of characterizing all parts of a protein and suggests a key role for the N‐terminal A'α extension of the LOV domain in controlling EL222 photocycle length.
Inhibiting mitochondrial inflammation through Drp1/HK1/NLRP3 pathway: A mechanism of alpinetin attenuated aging‐associated cognitive impairment
Authors: Chen Yuanyuan , Yang Chuan , Zou Mi , Wang Dan , Sheng Ruilin , Zhan Meng , Chen Qi , Yang Wenqin , Liu Xiao , Xu Shijun 
Published: February 2023

AbstractMitochondrial inflammation triggered by abnormal mitochondrial division and regulated by the Drp1/HK1/NLRP3 pathway is correlated with the progression of aging‐associated cognitive impairment (AACI). Alpinetin is a novel flavonoid derived from Zingiberaceae that has many bioactivities such as antiinflammation and anti‐oxidation. However, whether alpinetin alleviates AACI by suppressing Drp1/HK1/NLRP3 pathway‐inhibited mitochondrial inflammation is still unknown. In the present study, D‐galactose (D‐gal)‐induced aging mice and BV‐2 cells were used, and the effects of alpinetin on learning and memory function, neuroprotection and activation of the Drp1/HK1/NLRP3 pathway were investigated. Our data indicated that alpinetin significantly alleviated cognitive dysfunction and neuronal damage in the CA1 and CA3 regions of D‐gal‐treated mice. Moreover, D‐gal‐induced microglial activation was markedly reduced by alpinetin by inhibiting the Drp1/HK1/NLRP3 pathway‐suppressed mitochondrial inflammation, down‐regulating the levels of p‐Drp1 (s616), VDAC, NLRP3, ASC, Cleaved‐caspase 1, IL‐18, and IL‐1β, and up‐regulating the expression of HK1. Furthermore, after Drp1 inhibition by Mdivi‐1 in vitro, the inhibitory effect of alpinetin on Drp1/HK1/NLRP3 pathway was more evident. In summary, the current results implied that alpinetin attenuated aging‐related cognitive deficits by inhibiting the Drp1/HK1/NLRP3 pathway and suppressing mitochondrial inflammation, suggesting that the inhibition of the Drp1/HK1/NLRP3 pathway is one of the mechanisms by which alpinetin attenuates AACI.
Improvements to the parametrization of snow in AROME in the context of ice crystal icing
Authors: Wurtz Jean , Bouniol Dominique , Vié Benoît 
Published: February 2023

AbstractIce crystal icing (ICI) poses a threat nowadays for airplane pilots crossing the anvils of tropical mesoscale convective systems (MCSs). The use of fine‐scale operational numerical weather predictions as provided by the French limited‐area model AROME could help to better understand this phenomenon and to help its anticipation. To enable AROME to simulate ICI‐prone conditions, modifications of its single‐moment microphysical scheme Intercity‐Express 3 (ICE3) are tested. Using a temperature‐dependent snow particle distribution deeply impacts the organization and the ice phase of the simulated MCS. Notably, while the size of convective regions decreases, the size of anvil clouds increases and the low stratiform rain increases as well. As a result, by increasing the quantity of snow and decreasing the quantity of graupel, the simulation of ICI‐prone conditions in the anvils of convective systems is enabled. Using this parametrization, further modifications fine‐tune the representation of snow and further increase the size of the anvil cloud. The Marshall–Palmer snow distribution is replaced by a generalized gamma and the terminal fall velocities of snow hydrometeors are parametrized so that they are in closer agreement with observations.
Hydroxyl‐initiated oxidation processes of phenylenediamines treated by the atmospheric plasma: A theoretical study in gas phase
Authors: Xu Shaofeng , Zhong Xiaoxia , Guo Ying , Shi Jianjun 
Published: February 2023

AbstractThe low temperature atmospheric plasma are kinds of advanced oxidation processes (AOPs) reactors and have potential applications on gas cleaning and water treatment; however, the underlying reaction mechanisms of organic compounds degradation are not well understood. In this study, the gas phase multistep OH‐initiated dehydrogenations of p‐, m‐, and o‐phenylenediamine with C2h, C2, and C2 point groups were investigated using density functional theory. Intrinsic reaction calculations were performed for transition states at the M062X/Def2TZVPP level of theory. The distinct directed graphs of the predominant pathways are presented to elucidate the dehydrogenation processes of three isomers of phenylenediamines. The information reported in this paper reveals the AOPs of phenylenediamines.
Dual‐Gate GaAs‐Nanowire FET for Room Temperature Charge‐Qubit Operation: A NEGF Approach
Authors: Nag Chowdhury Basudev , Chattopadhyay Sanatan 
Published: February 2023

AbstractThe performance of dual‐gate GaAs‐nanowire field‐effect‐transistor (FET) is investigated as a charge‐qubit device operating at room temperature. In compatibility with the state‐of‐the‐art classical bit technology, it is shown that the single gate of a nanowire FET can be replaced by two localized gates to achieve such charge‐qubit operation. On application of relevant biases to the localized gates, two voltage tunable quantum dots are created within the nanowire channel with electrostatically controlled single‐state‐occupancy and interdot coupling leading to charge‐qubit operation at room temperature. The associated electron transport is theoretically modeled on the basis of nonequilibrium Green's function formalism. The “initialization” and “manipulation” for qubit operation are performed by applying suitable gate voltages, whereas the “measurement” is executed by applying a small drain bias to obtain a pulse current of ≈pA order. A ≈25 MHz frequency of coherent oscillation is observed for the qubit and a characteristic decay time of ≈ 70 ns is achieved. The results suggest that such dual gate nanowire FET is a promising architecture for charge‐qubit operation at room temperature.
Ferromagnetism Induced by Magnetic Dilution in Van der Waals Material Metal Thiophosphates
Authors: Peng Jin , Yang Xinyu , Lu Ziye , Huang Lin , Chen Xiyu , He Miao , Shen Jingdong , Xing Yu , Liu Meifeng , Qu Zhe , Wang Zhicheng , Li Linglong , Dong Shuai , Liu Jun‐Ming 
Published: February 2023

AbstractMetal thio(seleno) phosphates MPX3 attract considerable attention with potential application in spintronics and other types of devices. Here, ferromagnetism in an Ising type diluted magnetic semiconductor Fe1‐xZnxPS3 is reported. Bulk single crystals of Fe1‐xZnxPS3 have been synthesized via chemical vapor transport method and characterized by X‐ray diffraction. The weak ferromagnetism associated with spin/cluster spin glass emerges at 30% Zn doping. A nearly static ferromagnetic order is observed in the highly diluted magnets Fe0.1Zn0.9PS3. X‐ray photoemission measurements indicate introduction of holes and associated Fe3+ in samples with ferromagnetic order. Density functional theory calculations confirm the Ising‐type ferromagnetic state in highly diluted compounds with hole doping. The interplay between bound magnetic polarons induces impurity‐band‐exchange and superexchange interactions can explain the evolution of magnetism with Zn doping. The findings suggest that the magnetic diluted FePS3 system is a candidate for potential applications in magnetic devices, and its quantum mechanism should be explored by using microscopic techniques in the near future.
Carbon tax, energy policy, and sustainable development in Indonesia
Authors: Hartono Djoni , Indriyani Witri , Iryani Beta Septi , Komarulzaman Ahmad , Nugroho Anda , Kurniawan Robi 
Published: February 2023

AbstractThe effectiveness of carbon taxes has been subject to important debates on the sustainable development pathway. As an archipelagic country that is vulnerable to climate change, the impact of implementing this policy instrument is still understudied in the literature. This study examines the effect of carbon tax and recycling scenarios on the Indonesian economy by employing a dynamic computable general equilibrium (CGE). The result revealed that carbon tax revenue recycling combined with household transfer and investment yielded better GDP and employment rate than a household transfer only in the medium and long terms. Furthermore, the carbon tax revenue recycling on household transfer and renewable energy investment created energy intensity reductions. This study recommends implementing the tax by prioritizing specific sectors, setting appropriate tax levels, applying a transitional policy, and diversifying the investment strategy to align with the sustainable development pathway.