bluuebunny/crossref_metadata_2025_split huggingface dataset:
Conceptual framework of hybrid style in fashion image datasets for machine learning
Authors: An Hyosun , Lee Kyo Young , Choi Yerim , Park Minjung 
Published: May 2023

AbstractFashion image datasets, in which each fashion image has a label indicating its design attributes and styles, have contributed to the achievement of various machine learning techniques in the fashion industry. Computer vision studies have investigated labeling categories (such as fashion items, colors, materials, details, and styles) to create fashion image datasets for supervised learning. Although a considerable number of fashion image datasets has been developed, different style classification criteria exist because of a lack of understanding concerning fashion style. Since fashion styles reflect various design attributes, multiple styles can often be included in a single outfit. Thus, this study aims to build a Hybrid Style Framework to develop a fashion image dataset that can be efficiently applied to supervised learning. We conducted focus group interviews with six fashion experts to determine fashion style categories with which to classify hybrid styles in fashion images. We developed 1,206,931K-fashion image datasets and analyzed the hybrid style convergence. Finally, we applied the datasets to the machine learning model and verified the accuracy of the computer’s ability to recognize style. Overall, this study concludes that the Hybrid Style Framework and developed K-fashion image datasets are helpful, as they can be applied to data-driven fashion services to offer personalized fashion design solutions.
Serum Midkine for AFP-negative hepatocellular carcinoma diagnosis: a systematic review and meta-analysis
Authors: Thokerunga Erick , Kisembo Peter , FangFang Huang , Zi Wang , Yu Zhang , Bongolo Christian Cedrick , Tu Jiancheng 
Published: May 2023

Abstract
Introduction
To date, alpha-feto protein (AFP) remains the most widely used serum biomarker for hepatocellular carcinoma (HCC) diagnosis and prognosis. However, its role has become controversial as close to 30% of early stage HCC patients are AFP negative. Different studies on the diagnostic performance of novel AFP-negative HCC biomarkers have shown inconsistent results of sensitivity, specificity, and area under the receiver operating curve (AUROC). Here, we conducted a systematic review and meta-analysis to resolve this inconsistency.

Methods
Relevant studies were systematically searched from PubMed, Embase, Cochrane library, Scopus, and the China National Knowledge Infrastructure (chkd-cnki) databases up to the 20th October 2022. The Newcastle–Ottawa Scale was used to assess the methodological quality of included studies. Sensitivity, specificity, and area under the curve were pooled using the random effect model.

Results
Five studies, with a total of 286 patients, were included. Serum Midkine was assessed using enzyme-linked immunosorbent assay (ELISA) in all the studies, at diagnostic thresholds varying from 0.387 to 5.1 ng/ml. The summary estimates for serum Midkine were 76% (95% CI 70–81%) sensitivity, 85% (95% CI 82–87%) specificity, and 91% area under the receiver operating characteristic curve (AUC), while the pooled diagnostic odds ratio (DOR) was 27.64 (95% CI 4.95–154.17).

Conclusion
Based on these findings, serum Midkine is a very promising diagnostic biomarker for AFP-negative HCC and should be validated further in large cohort studies.
Coexistence of pulmonary tuberculosis with pulmonary sarcoidosis and skin sarcoidosis: a case report
Authors: Yusuf Khalifa Abdulrahman , Kanhosh Shadi Fayez , Al-Madani Abdulrahman Hasan 
Published: May 2023

Abstract
Background
Necrotising granulomatous diseases of the lungs exhibit a narrow range of differential diagnoses. Tuberculosis accounts for most of these cases, while sarcoidosis is an uncommon entity in this group but both possess similar clinical and radiological similarities. One must consider a diagnosis of sarcoidosis once the standard anti-mycobacterial medications fail to achieve a clinical improvement. The case described highlights the coexistence of tuberculosis and sarcoidosis which is a rare entity in the medical literature.

Case presentation
A 57-year-old male presented with respiratory symptoms and was diagnosed with tuberculosis (TB) demonstrating a polymerase chain reaction (PCR) test positive showing microbial DNA in bronchial washing. The patient started standard anti-TB treatment; however, he did not respond initially. Further investigations led us to diagnose pulmonary followed by skin sarcoidosis, based on histology. After confirmation of sarcoidosis, administered corticosteroids for 6 months simultaneously along with anti-TB treatment; however, anti-TB treatment was prolonged for a total of 9 months. The patient was found clinically symptomless after the completion of treatment during subsequent follow-ups.

Conclusion
The use of corticosteroids as an adjunct with standard anti-TB treatment proves beneficial effects on the recovery of patients having a coexistence of pulmonary mycobacterium tuberculosis and sarcoidosis disease conditions.
Delayed post-traumatic intractable epistaxis due to pseudoaneurysms in concha bullosa: a case report
Authors: Jain Shraddha , Murali Mithula , Hande Vaidehi , Ranjan Aditya , Banode Pankaj , Shekawat Rupesh 
Published: May 2023

Abstract
Background
Delayed post-traumatic bleeding at various sites is known due to vascular abnormalities related to structural changes in the vessel walls, in the form of pseudo aneurysms and arteriovenous malformations. Delayed epistaxis following facial trauma is a distinct entity that presents as recurrent episodes of bleeding from the nose. History of trauma is important to differentiate it from idiopathic intractable epistaxis, the management of which is less dramatic in the beginning in the form of endoscopy and electrocauterization. However, uncontrolled post-traumatic delayed epistaxis usually requires embolization. We report a rare case of intractable epistaxis associated with multiple pseudoaneurysms (PA), due to bleeding inside concha bullosa, where even embolization was unsuccessful.

Case presentation
A 25-year-old male patient presented to casualty and was referred to the Otorhinolaryngology department for recurrent profuse bleeding from left nasal cavity, where conservative measures like nasal packing, and electrocauterization did not help. Patient had a history of fall from height with facial bone fractures 1 month back. Angiography revealed blush with dilatation (pseudoaneurysms) in the nasal branches of internal maxillary arteries, ascending pharyngeal and labial arteries and embolization was done in the Interventional Radiology Department. Post-embolization, the patient again developed massive epistaxis. The patient was explored under general anaesthesia, to find out the site of bleed by nasal endoscopy. Collected blood was found in the left concha bullosa. Conchoplasty of the left middle turbinate was done with cauterization of bleeding vessels. The patient had no further epistaxis and was discharged in stable condition. He is asymptomatic for the last 6 months.

Conclusion
Post-traumatic pseudoaneurysms is a rare cause of delayed epistaxis following nasal trauma. Angiography helps in the localization of the source of bleeding inside nasal cavity and can identify pseudoaneurysmal dilatations of vessels. Our case highlights the importance of hidden bleeding points inside concha bullosa as a source of intractable epistaxis unresponsive to embolization.
Dynamical approach to shortcuts to adiabaticity for general two-level non-Hermitian systems
Authors: Luan T. Z. , Sun J. Y. , Shen H. Z. 
Published: May 2023

Abstract
In this Letter, we apply a class of general two-level non-Hermitian Hamiltonians whose off-diagonal elements are neither equal nor conjugate of each other to study the dynamical approach to shortcut to adiabaticity which is based on engineering the Hamiltonian and dynamical properties of the system to remove any unwanted probability amplitude or implant the desired probability amplitude. Using the special characteristics that one of the eigenvalues of the general two-level non-Hermitian Hamiltonian is real and the other is complex, we can decay (amplify) the population exponentially in the undesired (desired) eigenstate, and maintain the conservation of probability amplitude of the other eigenstate. Applying this approach to general two-level non-Hermitian systems, we find that the efficient population transfer can be achieved by our method, which works even in almost instantaneous manner and has a lower cost compared with the common approach of shortcut to adiabaticity.
Occurrence of connected clusters in motility-induced phase-separated states of persistent active particles at zero temperature
(a)
Authors: Schmiedeberg M. 
Published: May 2023

Abstract
To study the interplay of the formation of clusters of overlapping particles and motility-induced phase separation in the zero temperature limit in two dimensions, we consider a simple model system consisting of a bidisperse mixture of disks that are only subject to a repulsion force in case of overlaps and an active force. The orientation of the disks is chosen randomly in the beginning and does not change anytime during the simulation thus corresponding to an infinite persistence length. Simulations with our model system reveal that clusters of overlapping particles occur in the dense phase of a phase-separated state in case of intermediate values of the ratio of active to repulsive force. However, for smaller activities there are only a few overlaps between the particles in the dense phase and the coexistence region ends at a packing fraction below the onset of the formation of clusters with overlapping particles. For large activities small clusters corresponding to small patches of the dense phase are found that are unstable due to the activity. Finally, the occurrence of connected clusters affects the phase separation. Our findings on how cluster formation and phase separation are related are relevant to many active particle systems as after adding thermal noise our model system corresponds to a system of active Brownian particles that have been intensely studied in recent years. Further extensions by adding friction, inertia, or more complex interactions are possible.
A zebrafish model of combined saposin deficiency identifies acid sphingomyelinase as a potential therapeutic target
Authors: Zhang Tejia , Alonzo Ivy , Stubben Chris , Geng Yijie , Herdman Chelsea , Chandler Nancy , Doane Kim P. , Pluimer Brock R. , Trauger Sunia A. , Peterson Randall T. 
Published: May 2023

ABSTRACTSphingolipidoses are a subcategory of lysosomal storage diseases (LSDs) caused by mutations in enzymes of the sphingolipid catabolic pathway. Like many LSDs, neurological involvement in sphingolipidoses leads to early mortality with limited treatment options. Given the role of myelin loss as a major contributor toward LSD-associated neurodegeneration, we investigated the pathways contributing to demyelination in a CRISPR-Cas9-generated zebrafish model of combined saposin (psap) deficiency. psap knockout (KO) zebrafish recapitulated major LSD pathologies, including reduced lifespan, reduced lipid storage, impaired locomotion and severe myelin loss; loss of myelin basic protein a (mbpa) mRNA was progressive, with no changes in additional markers of oligodendrocyte differentiation. Brain transcriptomics revealed dysregulated mTORC1 signaling and elevated neuroinflammation, where increased proinflammatory cytokine expression preceded and mTORC1 signaling changes followed mbpa loss. We examined pharmacological and genetic rescue strategies via water tank administration of the multiple sclerosis drug monomethylfumarate (MMF), and crossing the psap KO line into an acid sphingomyelinase (smpd1) deficiency model. smpd1 mutagenesis, but not MMF treatment, prolonged lifespan in psap KO zebrafish, highlighting the modulation of acid sphingomyelinase activity as a potential path toward sphingolipidosis treatment.
In a marine teleost, the significance of oxygen supply for acute thermal tolerance depends upon the context and the endpoint used
Authors: Nati Julie J. H. , Blasco Felipe R. , Rodde Charles , Vergnet Alain , Allal François , Vandeputte Marc , McKenzie David J. 
Published: May 2023

ABSTRACT
Eight juvenile European seabass were exposed to two thermal ramping protocols with different levels of aerobic activity and tolerance endpoint: the critical thermal maximum for swimming (CTSmax) while exercising aerobically until fatigue and the critical thermal maximum (CTmax) under static conditions until loss of equilibrium (LOE). In the CTSmax protocol, warming caused a profound increase in the rate of oxygen uptake (ṀO2), culminating in a gait transition from steady aerobic towards unsteady anaerobic swimming, then fatigue at 30.3±0.4°C (mean±s.e.m.). Gait transition and fatigue presumably indicate an oxygen limitation, which reflects the inability to meet the combined demands of swimming plus warming. The CTmax protocol also elicited an increase in ṀO2, culminating in LOE at 34.0±0.4°C, which is significantly warmer than fatigue at CTSmax. The maximum ṀO2 achieved in the CTmax protocol was, however, less than 30% of that achieved in the CTSmax protocol. Therefore, the static CTmax did not exploit full cardiorespiratory capacity for oxygen supply, indicating that LOE was not caused by systemic oxygen limitation. Consequently, systemic oxygen supply can be significant for tolerance of acute warming in seabass but this depends upon the physiological context and the endpoint used.
A diminutive snake species can maintain regional heterothermy in both homogeneous and heterogeneous thermal environments
Authors: Cox Christian L. , Chung Albert K. , Davoll Myles E. , DeHart Steph A. , Gerardi Samuel T. , Ly Tony K. , Moxley Kyle , Nipper Preston T. , Novak Delaney R. , Reeves Phillip F. , Williams Becky J. , Logan Michael L. 
Published: May 2023

ABSTRACT
Regional heterothermy is a pattern whereby different body regions are maintained at different temperatures, often to prioritize the function of certain body parts over others, or to maximize the function of organs and tissues that vary in thermal sensitivity. Regional heterothermy is relatively well understood in endotherms, where physiological mechanisms maintain heterogeneity. However, less is known about regional heterothermy in ectotherms, where behavioral mechanisms are more important for generating thermal variation. In particular, whether small and elongate ectotherms with high surface area to volume ratios such as diminutive snakes can maintain regional heterothermy, despite rapid thermal equilibration, is not yet known. We measured regional variation in body temperature and tested whether environmental heterogeneity is used to generate regional heterothermy in the ring-necked snake (Diadophis punctatus) using both field and laboratory studies. We found that ring-necked snakes have robust regional heterothermy in a variety of contexts, despite their small body size and elongate body shape. Temperature variation along the length of their bodies was not detectable when measured externally. However, snakes had higher mouth than cloacal temperatures both in the field and in laboratory thermal gradients. Further, this regional heterothermy was maintained even in ambient laboratory conditions, where the thermal environment was relatively homogeneous. Our results indicate that regional heterothermy in ring-necked snakes is not solely driven by environmental variation but is instead linked to physiological or morphological mechanisms that maintain regional variation in body temperature irrespective of environmental context.
Ultra-low radiation dose and contrast volume CT protocol and TAVI-CT score for TAVI planning and outcome
Authors: Fogante Marco , Esposto Pirani Paolo , Cela Fatjon , Balardi Liliana , Piva Tommaso , Argalia Giulio , Schicchi Nicolò 
Published: May 2023

Objective: To investigate the feasibility of an ultra-low radiation dose and contrast volume protocol using third-generation dual-source (DS) CT for transcatheter aortic valve implantation (TAVI) planning with coronary artery disease (CAD) assessment, coronary artery calcium score (CACS) and aortic valve calcium score (AVCS) quantification and to evaluate their relationship with TAVI outcome. Methods: In this retrospective study were selected 203 patients (131 males, 79.4 ± 5.4 years) underwent to TAVI and at 30- and 90-day follow-up. All patients had performed a third-generation 2 × 192-slices DSCT. The CT protocol included a non-contrast and a contrast high-pitch aortic acquisition for TAVI planning and CAD assessment. Semi-qualitative and quantitative image analysis were performed; the performance in CAD assessment was compared with ICA; the relationship between AVCS and CACS and paravalvular aortic regurgitation (PAR) and major cardiovascular events (MACEs) were evaluated. Mean radiation dose were calculated. Non-parametric tests were used. Results: Semi-qualitative image analysis was good. Contrast enhancement >500 Hounsfield unit (HU) and contrast-to-noise ratio <20 were obtained in all segments. The diagnostic accuracy in CAD was 89.0%. AVCS was significantly higher in patients with 30-day severe PAR. AVCS and CACS were higher in patients with 90-day MACE complications, respectively, 1904.5 ± 621.3 HU (p < 0.0001) and 769.2 ± 365.5 HU (p < 0.0230). Mean radiation dose was 2.8 ± 0.3 mSv. Conclusion: A TAVI planning ultra-low radiation dose and contrast volume protocol using third-generation DSCT provides highly diagnostic images with CAD assessment, AVCS and CACS quantification and these latter were related with TAVI outcomes. Advances in knowledge: The proposed protocol using third-generation 2 × 192-slices DSCT allows with an ultra-low radiation dose and contrast volume the TAVI planning and the coronary artery assessment.
FORECASTING SALES OF AN INNOVATIVE PRODUCT BASED ON SIMULATION MODELING
Authors: Gajkova Luybov V. 
Published: May 2023

The use of simulation modeling for forecasting sales of an innovative product is considered as one of the methods of regulating sales in the conditions of digitalization of the economy.
Purpose: construction of a simulation model for forecasting the sale of an innovative product in order to maintain an appropriate level of life activity of the able-bodied population in the conditions of digitalization of the economy.
Methodology: the dialectical method is used as a general scientific method of cognition; techniques and tools of system, comparative analysis and generalization; methods and tools of simulation modeling.
Results: an approach to the study of sales forecasts of an innovative product based on discrete-event simulation modeling as the basis of analytical processing of the obtained data is described.
Scope of results: the heads of companies in solving the issues of determining the optimal volume of sales of an innovative product as one of the components of the element of market infrastructure in the conditions of digitalization of the economy.
DEVELOPMENT OF A RESOURCE MANAGEMENT METHODOLOGY FOR A SERVICE COMPANY
Authors: Avetisyan Tatiana V. , Lvovich Yakov E. , Preobrazhenskiy Andrey P. , Preobrazhensky Yuri P. 
Published: May 2023

This article discusses the specifics of managing a service-related company. It shows how the preparation of input data and their transformation takes place. Peculiarities of model preparation for training and testing are demonstrated. The general scheme of interaction between customer end-users and project and third-party technical support taking into account the conditions of service maintenance is given. The scheme of logic of processing incoming incidents between support lines is shown. The logic diagram of the prediction module for determining the support team is given. After the work has received the trained model that allows to carry out prediction of a support team on the basis of methods of logistic regression, by means of language Python it can be saved as a special file, it can then be connected as an independent module.
Purpose. Determination of methods and techniques of analysis used in the analysis of export operations.
Methodology the article used systems analysis and enterprise management methods.
Results: an example of resolved incident data for a specific support team with engineers is considered, as well as an example of numerical feature calculations to adjust the support team engineer’s baseline prediction. A logic diagram of the improved software solution model is shown.
Practical implications can be used with the improvement of IT service management in terms of incident coordinator activities.
ASSESSING THE COINTEGRATION OF INFLATION AND PRODUCTIVITY: THE EXAMPLE OF RUSSIA AND THE COUNTRIES OF THE WEST AFRICAN ECONOMIC AND MONETARY UNION (UEMOA)
Authors: Portnov Aleksandr V. , Viku Kojovi Nelson Krepin V. 
Published: May 2023

The article presents an assessment of the cointegration of inflation and productivity indicators on the example of: Russia and UEMOA countries. As part of the study, an attempt was made to assess the presence of a long-term balance between the studied indicators for a more detailed understanding of the economic nature of two categories: “productivity” and “inflation”. The spatial aspect was chosen by the authors not by chance, since it allowed the analysis to be carried out, considering the peculiarities of different countries in presenting data with different frequencies: if monthly data are available, this provides long time series, cointegration, which can be estimated by the classical method. In the case of annual data, the time series are short, and the authors propose to evaluate the cointegration of such series using a nonparametric method. The article presents a comparative analysis of the results obtained for the countries under study based on the use of parametric and non-parametric estimation methods. The non-parametric method for assessing the probability of cointegration was used for the first time in the context of inflation and productivity indicators.
Purpose. Determine the cointegration of inflation and labor productivity as an assessment of economic development.
Methodology: parametric and non-parametric methods for assessing cointegration were used in the article.
Results: data were obtained comparing the probabilities of cointegration of inflation and labor productivity, considering the territorial aspect and the level of economic development.
Practical implications: application of a non-parametric method for assessing cointegration in the framework of economic analysis.