bluuebunny/crossref_metadata_2025_split huggingface dataset:
Online education and its effect on teachers during COVID-19—A case study from India
Authors: Dayal Surbhi 
Published: March 2023

Background
COVID pandemic resulted in an initially temporary and then long term closure of educational institutions, creating a need for adapting to online and remote learning. The transition to online education platforms presented unprecedented challenges for the teachers. The aim of this research was to investigate the effects of the transition to online education on teachers’ wellbeing in India.

Methods
The research was conducted on 1812 teachers working in schools, colleges, and coaching institutions from six different Indian states. Quantitative and qualitative data was collected via online survey and telephone interviews.

Results
The results show that COVID pandemic exacerbated the existing widespread inequality in access to internet connectivity, smart devices, and teacher training required for an effective transition to an online mode of education. Teachers nonetheless adapted quickly to online teaching with the help of institutional training as well as self-learning tools. However, respondents expressed dissatisfaction with the effectiveness of online teaching and assessment methods, and exhibited a strong desire to return to traditional modes of learning. 82% respondents reported physical issues like neck pain, back pain, headache, and eyestrain. Additionally, 92% respondents faced mental issues like stress, anxiety, and loneliness due to online teaching.

Conclusion
As the effectiveness of online learning perforce taps on the existing infrastructure, not only has it widened the learning gap between the rich and the poor, it has also compromised the quality of education being imparted in general. Teachers faced increased physical and mental health issues due to long working hours and uncertainty associated with COVID lockdowns. There is a need to develop a sound strategy to address the gaps in access to digital learning and teachers’ training to improve both the quality of education and the mental health of teachers.
Community exposures among Colorado adults who tested positive for SARS-CoV-2 –A case-control study, March-December 2021
Authors: White Alice E. , Tran Amanda D. , Torok Michelle R. , Jervis Rachel H. , Albanese Bernadette A. , Buchwald Andrea G. , Schmoll Emma , Stringer Ginger , Herlihy Rachel K. , Scallan Walter Elaine J. 
Published: March 2023

Objectives
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, which causes coronavirus disease 2019 (COVID-19), is spread primarily through exposure to respiratory droplets from close contact with an infected person. To inform prevention measures, we conducted a case-control study among Colorado adults to assess the risk of SARS-CoV-2 infection from community exposures.

Methods
Cases were symptomatic Colorado adults (aged ≥18 years) with a positive SARS-CoV-2 test by reverse transcription-polymerase chain reaction (RT-PCR) reported to Colorado’s COVID-19 surveillance system. From March 16 to December 23, 2021, cases were randomly selected from surveillance data ≤12 days after their specimen collection date. Cases were matched on age, zip code (urban areas) or region (rural/frontier areas), and specimen collection date with controls randomly selected among persons with a reported negative SARS-CoV-2 test result. Data on close contact and community exposures were obtained from surveillance and a survey administered online.

Results
The most common exposure locations among all cases and controls were place of employment, social events, or gatherings and the most frequently reported exposure relationship was co-worker or friend. Cases were more likely than controls to work outside the home (adjusted odds ratio (aOR) 1.18, 95% confidence interval (CI): 1.09–1.28) in industries and occupations related to accommodation and food services, retail sales, and construction. Cases were also more likely than controls to report contact with a non-household member with confirmed or suspected COVID-19 (aOR 1.16, 95% CI: 1.06–1.27).

Conclusions
Understanding the settings and activities associated with a higher risk of SARS-CoV-2 infection is essential for informing prevention measures aimed at reducing the transmission of SARS-CoV-2 and other respiratory diseases. These findings emphasize the risk of community exposure to infected persons and the need for workplace precautions in preventing ongoing transmission.
Analisis Risiko Bunuh Diri pada Mahasiswa Kesehatan di Kota Banda Aceh
Authors: Novitayani Sri , Nurhidayah Irfanita 
Published: March 2023

Background: Suicide is the main cause of death for students. Some studies report that half of college students have felt so depressed that they were useful. College life can be a time of high stress. This study aims to describe the risk of suicide in health students in Banda Aceh.Methods: This type of research is a quantitative research using a descriptive correlative method. The sampling technique in this study used purposive sampling with a sample of 171 students. Data collection method using Adult Suicidal Ideation Questionnaire (ASIQ).Result: The majority of respondents were health students from the Faculty of Nursing (67.3%), female (88.9%), 2016 class (50.9%), adult (90.6%), from high school (84 ,8%), both parents are still alive (85.4%), have parents who work as civil servants (52.6%), and live in a boarding house/rent (50.3%). The age of the students in this study was between 18 years to 23 years. The majority of health students at Syiah Kuala University experienced a low risk of suicide (87.7%).Conclusion : It can be concluded that health students have a suicide risk which is characterized by thoughts related to suicidal ideation, but these ideas rarely appear so that their suicide risk category is low.
Treatment Outcome of Tuberculosis Cases and HIV Co-infected Patients. A Retrospective Study at a Federal Medical Centre of North Central Nigeria
Authors: Eze Thaddues Okonkwo , Nwadinigwe Finian Chimezie , Ameh Gabriel Mathias 
Published: March 2023

Background: Tuberculosis (TB) is the leading cause of death among people living with HIV/AIDS worldwide. Despite the availability of highly effective treatment for decades, Tuberculosis (TB) remains a major health problem in Nigeria due to the increasing association between HIV and TB observed over the past three decades when HIV was discovered. However, the proportion of TB and or TB/HIV co-infected patients who have successful TB treatment outcome is not well known. This study determined the treatment outcome of TB/HIV co-infected patients with HIV negative patients at Federal Medical Centre Makurdi, Benue State, Nigeria. Methods: A retrospective study that used secondary data from Directly Observed Treatment Short (DOTS) course center (APIN Unit). 268 cases were considered and the period under review covers from January, 2019 to December, 2021. Results: Out of the total 268 TB cases reviewed, the HIV prevalence rate was 28.7 %. More than two-third (78.4%) of HIV-negative patients had successful treatment compared to 68.9% of HIV positive patients that were treated successful. Out of the 77 HIV co-infected patients, 10.4% defaulted, 14.2% had died, and 6.5% failed treatment compared to HIV-negative patients amongst whom 15.2% defaulted, 4.8% died and 1.6% failed treatment. TB/HIV co-infection was significantly associated with poor treatment outcome (AOR: 1.158; 95 % CI 0.617-2.173; p = 0.648).Conclusion: The favorable treatment outcome of HIV-negative patients is more than that of HIV-positive patients and the most probable predictable factor responsible is the CD4 count of patient; indicating that TB/HIV co-infection has remained a major public health problem in Benue state. Therefore, there is the need for sustained strengthening and expansion of the national TB/HIV programmes.
The influence of transition metal ions on the oxidation of kraft pulp using hydrogen peroxide under mildly acidic conditions
Authors: Martinsson Axel , Hasani Merima , Theliander Hans 
Published: March 2023

Abstract
Oxidation of kraft pulp using hydrogen peroxide under mild acidic conditions can be applied in order to obtain new functionality of the fibres, in the form of carbonyl groups. The hydrogen peroxide concentration must, however, be higher than consumed by the oxidation reactions meaning that the liquid must be recirculated to fully utilize the hydrogen peroxide. This paper investigates the consequences of recirculation of the oxidation liquor. It was found that recirculation results in an accumulation of ions of transition metals (copper, iron and manganese) in the oxidation liquor. The transition metal ions are known for catalytic decomposition of hydrogen peroxide, producing radicals which may react with carbohydrates, forming carbonyl groups as well as causing carbohydrate degradation. This was confirmed through the recirculation of oxidation liquor as well as through controlled addition of transition metals. At high transition metal ion concentration the reactions were fast and a severe degradation of carbohydrates was observed, accompanied by a rapid hydrogen peroxide consumption. The consequence of this, in an industrial context, is that the concentration of metal ions must be carefully controlled in order to add functionality to the cellulose without causing excessive degradation of carbohydrates or consumption of hydrogen peroxide.
Glorifying Francis Xavier’s (1506–1552) Good Deeds or Miracles? The Negotiation of Sanctity in Daniello Bartoli’s Asia (1653)
Authors: Frei Elisa 
Published: March 2023

Abstract
This essay focuses on Francis Xavier (1506–1552), the first saint of the Society of Jesus, canonised with its founder Ignatius of Loyola in 1622, and three differing perceptions of his sanctity, both within his own religious order and outside it. The work of Alessandro Valignano gives a first introduction soon after Xavier’s death, with complaints about how most of the testimonies of the future saint were exaggerated and not particularly edifying (1580s). The second text is the manuscript Relatio Rotae (1619), commissioned by Pope Paul V for Xavier’s canonisation, which contains many pages testifying to the same miracles and prophecies Valignano criticised. The final and main source is the treatise Asia by Daniello Bartoli (1653). The Ferrarese Jesuit dedicated the first half of it to Xavier’s life and death, and drew from multiple sources, always proud of his historical detachment, sobriety, and discretion. The examination of these sources highlights all of the negotiations involved in sanctity, especially in such an important period for the Roman Catholic Church in general, and for the Society of Jesus in particular.
1622, the Fatal Year for the Discalced Carmelites: The Canonisation of Teresa, the Crystallisation of Conventual Typologies, and the Reinvention of Iconography
Authors: Sturm Saverio 
Published: March 2023

Abstract
1622 was a crucial year for the Discalced Carmelite Order. This essay intends to highlight and connect a series of events surrounding the fateful canonisation of the foundress Teresa of Ávila on 12 March 1622. On 6 January of that year, the Congregation of Propaganda Fide had been founded with the fundamental contribution of Carmelite missionaries. On 8 May 1622, the important Carmelite Church of San Paolo Apostolo in Rome was re-consecrated to Santa Maria della Vittoria, with celebrations and popular processions, in memory of the “victory” of the White Mountain in 1620 over the Protestant Bohemian troops, favoured by the intercession of Maximilian of Bavaria’s military chaplain, Carmelite Dominic of Jesus Maria. In the years that immediately followed, numerous male and female foundations dedicated to the newly-canonised St. Teresa proliferated in Rome and Italy, according to common iconographic and conventual models elaborated centrally by the order’s new hierarchies.
A Hieroglyphic seal from the cult centre of the city of Knossos (KN S (4/4) 01)
Authors: Kanta Athanasia , Palaima Thomas G. , Perna Massimo 
Published: March 2023

Abstract
The Hieroglyphic seal KN S (4/4) 01, found in the Neopalatial Room 3 of the Cult Centre of the City of Knossos, is a document of considerable importance in the study of Cretan script for several reasons.
With regard to iconography and palaeography, we have identified for the first time the true idealized form of sign 095, and that permits us to correct our understanding of the shape of other examples of the same sign and thereby to improve our knowledge of the palaeographical development of the Hieroglyphic script.
Furthermore, this new document preserves one more attestation of the socalled Arkhanes “formula” and shows a connection between this “formula” and the fraction signs.
Finally, this seal confirms also a relationship between this “formula” and the logogram *181 on the one hand and the sign 010 on the other hand.
Drei karische Verben
Authors: Schürr Diether 
Published: March 2023

Abstract
Mδ-, mδš, mδa und mδane, mlane und mλne sowie šRnne werden als Verbformen gedeutet: 3. P. Sg. Prat. mit Schwund der ‚lenierten‘, lykisch -de, lydisch -d und luwisch /-da/ entsprechenden Endung und teilweise einem angehangten Pronomen -ne, das ein Akkusativobjekt ersetzt. Im ersten Fall handelt es sich bei den Votivinschriften sicher um ein verbum donandi, das zu hethitisch manijahh- gehoren konnte, im zweiten kommt eine Bedeutung ‚schrieb‘ in Frage, wozu gotisch meljan verglichen werden konnte, im dritten ebenfalls ein verbum donandi.
Le dialecte grec de Pamphylie, supplément VII
Authors: Tekoğlu Recai , Köse Veli 
Published: March 2023

Abstract
The present study is the latest one of the supplements for Le dialecte grec de Pamphylie published by Cl. Brixhe in 1976. Eight new inscriptions belonging to the dialectal group are presented here. The contribution of the supplement VII to the onomastics of the Pamphylian dialect can be seen in the attestation of Εὐτυχᾶς, Ἀθμοπάτρας, Κτίσων and *Κουͷας.
Monitoring of sirolimus in the whole blood samples from pediatric patients with lymphatic anomalies
Authors: Treder Natalia , Plenis Alina , Maliszewska Olga , Kaczmarczyk Natalia , Olędzka Ilona , Kowalski Piotr , Bączek Tomasz , Bień Ewa , Krawczyk Małgorzata Anna , Roszkowska Anna 
Published: March 2023

Abstract
In recent years, off-label use of sirolimus (SIR) has been gaining attention in the clinical practice. However, since it is critical to achieve and maintain therapeutic blood levels of SIR during treatment, the regular monitoring of this drug in individual patients must be implemented, especially in off-label indications of this drug. In this article, a fast, simple, and reliable analytical method for determining SIR levels in whole blood samples is proposed. Sample preparation based on dispersive liquid–liquid microextraction (DLLME) followed by liquid chromatography-mass spectrometry (LC-MS/MS) was fully optimized toward the analysis of SIR and proposed as a fast, simple, and reliable analytical method for determining the pharmacokinetic profile of SIR in whole-blood samples. In addition, the practical applicability of the proposed DLLME-LC-MS/MS method was evaluated by analyzing the pharmacokinetic profile of SIR in whole blood samples obtained from two pediatric patients suffering from lymphatic anomalies, receiving this drug as off-label clinical indication. The proposed methodology can be successfully applied in routine clinical practice for the fast and precise assessment of SIR levels in biological samples, thus allowing SIR dosages to be adjusted in real time during pharmacotherapy. Moreover, the measured SIR levels in the patients indicate the need for monitoring between doses to ensure the optimal pharmacotherapy of patients.
Effects of osteogenic growth peptide C-terminal pentapeptide and its analogue on bone remodeling in an osteoporosis rat model
Authors: Ma Yuhang , Zhang Ying , Lin Yi , Ding Xiaoying , Zhang Yuntao 
Published: March 2023

Abstract
This study aimed to explore the effects of osteogenic growth peptide C-terminal pentapeptide (G36G), and its analog G48A on bone modeling in rats with ovariectomy-induced osteoporosis. Ovariectomized rats were administered PBS (OVX group), risedronate (RISE group), G36G combined with risedronate (36GRI group), G36G (G36G group), or G48A (G48A group). The sham-operation rats (SHAM group) were administered PBS. Serum osteocalcin and IGF-2 levels in the SHAM, OVX, G36G, G48A, and RISE groups were observably lower than the 36GRI group (P < 0.01) and the bone mineral density of the entire femur, distal metaphysis, and lumbar L1–L4 in the 36GRI group were notably increased (P < 0.05). The bending energy of the 36GRI group was prominently higher than the other groups (P < 0.05). Other features measured in the study that provided significant outcomes was the ratio of femora ash weight/dry weigh, parameters of trabecular bone volume (TBV)/total tissue volume, TBV/sponge bone volume, mean trabecular plate thickness, mean trabecular plate space, bone surface, parameters of sfract(s) and sfract(d), tetracycline-labeled, and osteoid surfaces. Bone loss in ovariectomized rats may be partially inhibited by G36G and G48A. A combination treatment with G36G and risedronate may be an effective intervention for osteoporosis.
Commercial Smart Watches and Heart Rate Monitors: A Concurrent Validity Analysis
Authors: Montalvo Samuel , Martinez Armando , Arias Sabrina , Lozano Alondra , Gonzalez Matthew P. , Dietze-Hermosa Martin S. , Boyea Bryan L. , Dorgo Sandor 
Published: March 2023

Abstract
Montalvo, S, Martinez, A, Arias, S, Lozano, A, Gonzalez, MP, Dietze-Hermosa, MS, Boyea, BL, and Dorgo, S. Smartwatches and commercial heart rate monitors: a concurrent validity analysis. J Strength Cond Res 37(9): 1802–1808, 2023—The purpose of this study was to explore the concurrent validity of 2 commercial smartwatches (Apple Watch Series 6 and 7) against a clinical criterion device (12-lead electrocardiogram [ECG]) and a field criterion device (Polar H-10) during exercise. Twenty-four male collegiate football players and 20 recreationally active young adults (10 men and 10 women) were recruited and participated in a treadmill-based exercise session. The testing protocol included 3 minutes of standing still (resting), then walking at low intensity, jogging at a moderate intensity, running at a high intensity, and postexercise recovery. The intraclass correlation (ICC2,k), and Bland-Altman plot analyses showed a good validity of the Apple Watch Series 6 and Series 7 with increased error (bias) as jogging and running speed increased in the football and recreational athletes. The Apple Watch Series 6 and 7 are highly valid smartwatches at rest and different exercise intensities, with validity decreasing with increased running speed. Strength and conditioning professionals and athletes can confidently use the Apple Watch Series 6 and 7 when tracking heart rate; however, caution must be taken when running at moderate or higher speeds. The Polar H-10 can surrogate a clinical ECG for practical applications.
Syncytial and Congregative Effects of Dengue and Zika Viruses on the Aedes Albopictus Cell Line Differ among Viral Strains
Authors: Liu Dongxiao , Obwolo Lilian Akello , Cruz-Cosme Ruth , Tang Qiyi 
Published: March 2023

Objective:
Dengue viruses (DENV) and Zika virus (ZIKV) are transmitted among humans, or from non-human primates to humans, through mosquito bites. The interaction of the virus with mosquito cells is a key step in the viral life cycle. Therefore, the objective of this study was to determine how DENV and ZIKV interact with mosquito cells.

Methods:
Immunofluorescence assays and a direct visualization system were combined to monitor the syncytial or congregative effects of DENV and ZIKV strains on C6/36 cells. We examined the cytopathic effects of the strains on C6/36 mosquito cells, a widely used laboratory model for studying infection with these viruses.

Results:
Our results indicated that all strains of DENV-1 and DENV-2, most DENV-4 strains, and some DENV-3 strains caused syncytial effects on C6/36 cells, whereas some DENV-3 and DENV-4 strains, and all tested ZIKV strains, caused cell congregation after infection but no cell fusion. In addition, we detected a range of environmental pH values from 6.0 to 8.0 supporting virus-induced cell fusion. The optimal pH condition was 7.5, at which viral production was also highest. Furthermore, the UV-inactivated virus did not cause cell fusion, thus suggesting that viral replication may be required for DENV’s syncytial effects on C6/36 cells.

Conclusion:
Syncytial and congregative effects of DENV and ZIKV on Aedes albopictus cells differ among viral strains. Syncytial effects of DENV on C6/36 are important for viral replication.
The third barrier to transgenerational inheritance in animals: somatic epigenetic resetting
Authors: Ewe Chee Kiang , Rechavi Oded 
Published: March 2023

After early controversy, it is now increasingly clear that acquired responses to environmental factors may perpetuate across multiple generations—a phenomenon termed transgenerational epigenetic inheritance (TEI). Experiments with Caenorhabditis elegans, which exhibits robust heritable epigenetic effects, demonstrated small RNAs as key factors of TEI. Here, we discuss three major barriers to TEI in animals, two of which, the “Weismann barrier” and germline epigenetic reprogramming, have been known for decades. These are thought to effectively prevent TEI in mammals but not to the same extent in C. elegans. We argue that a third barrier—that we termed “somatic epigenetic resetting”—may further inhibit TEI and, unlike the other two, restricts TEI in C. elegans as well. While epigenetic information can overcome the Weismann barrier and transmit from the soma to the germline, it usually cannot “travel back” directly from the germline to the soma in subsequent generations. Nevertheless, heritable germline memory may still influence the animal's physiology by indirectly modifying gene expression in somatic tissues.
School Dictionary of the Slovenian Language on the Franček Web Portal
Authors: Petric Žižić Špela 
Published: March 2023

This article presents the concept of the School Dictionary of the Slovenian Language (ŠSSJ), which is being made as part of the project Spletni portal Franček, Jezikovna svetovalnica za učitelje slovenščine in Šolski slovar slovenskega jezika (Franček Web Portal, Language Counselling for Slovenian Teachers and School Dictionary of the Slovenian Language). The School Dictionary of the Slovenian Language, which is a part of The Franček portal, the first specialized educational lexicographic-grammatic portal for Slovenian, brings a lexicographically informed, simplified display of information adapted to the abilities and knowledge of its youngest users. This article describes in greater detail the typology of explanations of nouns, verbs, adjectives and adverbs, which also includes explanations of nouns, verbs, adjectives, and adverbs’ phraseological and non-phraseological multi-word lexemes, the source for dictionary materials (together with the principles of including dictionary entries), the dictionary labels and grammatical information. Individual adjustments and simplifications are partly shown through comparison with the Dictionary of the Slovenian Standard Language (SSKJ).