bluuebunny/crossref_metadata_2025_split huggingface dataset:
Emergence of Hybrid CSR Models as a Conflict‐Driven Communicative Process in a Nordic Welfare State
Authors: Moisander Johanna , Eräranta Kirsi , Fahy Kathryn M. , Penttilä Visa 
Published: June 2023

AbstractThis paper offers an understanding of how hybrid models of corporate social responsibility (CSR) – models combining society‐centric mandatory (implicit) and business‐centric voluntary (explicit) approaches to CSR – are communicatively constructed through institutional struggles over the roles and responsibilities of business in society, in the context of a Nordic welfare state. We develop a model of hybridization as a dialectical process of communicative activity, framing and counter‐framing, in which conflict and contestation over normative understandings about CSR drive the process. The model explains the emergence of hybrid models of CSR in terms of gradually evolving issue development and frame changes that are driven by discursive struggles over moral obligations of business in society, appropriate configuration of legitimacy relationships, and appropriate institutional arrangements for CSR governance. In contrast to prevailing accounts, which tend to theorize hybridization as resulting from isomorphic, mimetic, and normative pressures, our account explicitly attends to the politics of hybridization.
Building design as a dynamic capability: A model for design integration
Authors: Sahakian Julie , BenMahmoud Jouini Sihem 
Published: June 2023

AbstractA growing number of firms have integrated design in order to foster innovation and growth. Recent literature acknowledges design as a capability leading to differentiation and competitive advantage. However, how such a capability is built within companies with no past experience in design has not been fully addressed. Our objective is to bridge this gap. Indeed, most existing contributions focus on design intervention, that is, using design in projects, rather than design integration, that is, its systematic use and long‐term engagement as an embedded practice in the organization. Based on a longitudinal case study of an insurance company, complemented with an investigation of five other firms from other sectors, we offer a model for building design as a dynamic capability: Triggered by strategic orientations, firms acquire design resources and deploy them in activities such as projects in order to produce tangible results. Capitalizing on what they have learned in these projects, they progressively consolidate this knowledge in an expertise, which is then shared and diffused, thereby renewing the firm's resources. Therefore, our model highlights a reinforcement dimension: In addition to an operational capability (designing, spreading, and managing design), it is also a regenerative capability that consists in building the design expertise, advocating for it, anchoring, and renewing it. We thus have two contributions: (i) We conceptualize design as a dynamic capability enabling the development of new offerings, processes, and strategies that lead to organizations' competitiveness and transformation, and (ii) we propose a model for building such a capability.
Survey to evaluate the proficiency in the use of antibacterial drugs in shrimp farming in the state of Sonora, Mexico
Authors: Estrada‐San Agustín Enrique , Hernández‐López Jorge , De Blas Ignacio , Sumano Héctor 
Published: June 2023

AbstractAntibiotic drugs (ABD) are often used in shrimp farms to treat the disease when a bacterial diagnosis is presumed. This scenario was the impetus to carry out a field survey to define how ABD are employed in the State of Sonora, the second largest producer of shrimp in Mexico. Twenty‐nine farms were surveyed through their general managers. According to interviews conducted, the most frequent bacterial diseases that were treated with antibiotics in 2020 were: Acute Hepatopancreatic Necrosis Disease (65%), vibriosis (51%), and Necrotizing hepatopancreatitis bacterium (41%). The most common ABDs were enrofloxacin, oxytetracycline and florfenicol, and drug preparations employed were often intended for non‐aquaculture species, mainly poultry, and pigs. The main criteria for selecting a given antibiotic was a direct recommendation, followed by the market price. Neither pharmacokinetics nor pharmacodynamics nor harvesting withdrawal time were taken into account. The absence of protocols to safeguard the health and integrity of workers was detected, training programs for the responsible use of ABD were not encountered, and no data on bacterial resistance to ABD is available in this region. It is concluded that at least formal studies to define the pharmacokinetics of antibiotics are needed to rationalize their use in shrimp production.
Accumulating awareness on the clinical significance and relevance of frailty in cirrhosis: Time to dig deeper into mechanistic basis!
Authors: Deng You , Hui Yangyang , Cui Binxin , Xie Wen , Sun Chao 
Published: June 2023

AbstractFrailty corresponds to an emerging construct in the hepatology which is originally introduced as a validated geriatric syndrome regarding increased vulnerability to pathophysiological stressors. As for patients with cirrhosis, the presence of frailty is indicative of debilitating conditions that subjects are prone to deleterious acute insults and have difficulties to restore even if the underlying liver function partially returned to normal levels. Since this conceptual development, a variety of tools assessing frailty have been proposed and evaluated in the context of cirrhosis. A recent performance‐based metric for frailty, designated as Liver Frailty Index, has broadly been applied in patients with cirrhosis and exhibited acceptable predictive ability in relation to disease progression, mortality and hospitalization. However, those functional tests measuring frailty may be impossible to perform in circumstance that patients are critically ill or undergoing detrimental events. An interesting modality indicates the use of alternative tests to evaluate frailty, which may be more adaptable and of choice for specific subgroups. The interrelation between frailty and various cirrhosis‐associated pathological entities is of clinical importance and implication. Noticeably, it is imperative to clarify these complex linkages to highlight novel therapeutic targets or interventional endpoints. The efficient and effective management of frailty is still challenging, but many attempts have been made to overcome barriers of affordability and availability. Some clinical trials on small scale revealed that home‐based exercise and individualized nutrition therapy show benefits in patients with cirrhosis, and high adherence to the treatment regimen may direct better efficacy and performance.
Platonic qua predication
Authors: Barney Rachel 
Published: June 2023

AbstractPlatonic arguments often have premises of a particular form which is misunderstood. These sentences look like universal generalizations, but in fact involve an implicit qua phrase which makes them a fundamentally different kind of predication. Such general implicit redoubled qua predications (girqps) are not an expression of Plato's proprietary views; they are also very common in everyday discourse. Seeing how they work in Plato can help us to understand them.
Global indicators and AI policy: Metrics, policy scripts, and narratives
Authors: Erkkilä Tero 
Published: June 2023

AbstractArtificial intelligence (AI) has become a global policy issue that is actively governed by international actors producing governance indicators. This article argues that despite the arguments about disruptions to governance and policy due to AI, the global rankings increasingly constitute a strong path dependence on AI policy, leading to conformity with existing policies and institutional practices of economic competitiveness. By analyzing the composition and data sources of global indices in competitiveness, innovation, human capital, and artificial intelligence, I will show how the global rankings now evolve by sharing data and concepts. Consequently, these metrics and related policy scripts promote the seeming continuity of current activities of global competitiveness. AI is discussed as a “revolution” but framed as a matter of “competitiveness,” “openness,” and “talent competition,” implying standard perceptions of economic competitiveness and innovation. There is also a narrative element in the policy script, as the future policies on AI are promoted with references to history that also project the past into the future. My article concludes that while path‐dependent policy indicators and related future narratives give a sense of orientation, they are problematic as they portray a seeming continuity of activities in times of disruptions, delimiting policy alternatives such as AI ethics.
Methylphenidate use and restorative treatment needs in young adults with attention deficit hyperactivity disorder
Authors: Schermann Haggai , Schiffmann Nathan , Ankory Ran , Shlaifer Amir , Yavnai Nirit , Yoffe Victoria , Natapov Lena 
Published: June 2023

AbstractObjectiveTo assess the effect and dose‐response of methylphenidate (MP) use on the restorative treatment needs in young adults with attention deficit hyperactivity disorder.Participants and methodsThis retrospective study comprises a cohort of military recruits aged 18–25 who served for 12 to 48 months between 2005 and 2017. The medical records of 213 604 participants were assessed of which: 6875 participants with ADHD who received treatment with MP, 6729 participants with ADHD who had no prescriptions for MP, and 200 000 healthy participants. The outcome was restorative treatment needs, which served as an indicator of caries: having at least one prescription for restorative treatment during the study period.ResultsFrequency of prescription for restorative treatment among the treated, the untreated and the control groups was 24%, 22%, and 17%, respectively (p < .0001). On multivariate analysis, the dose‐response association between MP use and the odds of having at least one restorative treatment was confirmed (OR = 1.006 for each additional 1 gr of MP; 95% CI [1.004:1.009])ConclusionsParticipants with ADHD who receive chronic treatment with MP have higher restorative treatment needs than participants with untreated ADHD and healthy participants. Our results show that chronic MP medication among young adults leads to an elevated need for restorative treatment and implies a significant impact on oral health (OH).
The challenging management of Moebius syndrome using orthodontic camouflage: A case report
Authors: Duggal Isha , Zere Edlira , Kumar Chaudhari Prabhat , Duggal Ritu , Singh Rana Shailendra , Chauhan Anuj 
Published: June 2023

AbstractMoebius syndrome (MS) is a rare congenital neuromuscular disorder characterized by weakness or paralysis (palsy) of abducens and facial nerves, or other cranial nerves which may be affected. Diagnosis, treatment, and dental management of MS patients are focused on treating manifestations like malocclusion, while catering to associated extraoral (neurologic, dermatologic, ocular) complications, aiming to improve their quality of life. Here, we report the case of a 9‐year‐old female patient with MS who underwent orthodontic camouflage using combined orthopedic‐orthodontic therapy using a high‐pull chin cup and fixed orthodontic appliance to improve skeletal mal‐relation and facial appearance. The outcome displayed great improvement in function and better esthetics, improving not only the patient's but also the family's quality of life. A year's follow‐up showed successful maintenance of the achieved results. A multidisciplinary approach in MS not only helps in overcoming the treatment challenges but also provides great psychosocial benefits to these patients.
What if muscle spindles were also involved in the sense of effort?
Authors: Monjo Florian , Allen Trevor 
Published: June 2023

AbstractEffort perception is widely acknowledged to originate from central processes within the brain, mediated by the integration of an efference copy of motor commands in sensory areas. However, in this topical review, we aim to challenge this perspective by presenting evidence from neural mechanisms and empirical studies that suggest that reafferent signals from muscle spindles also play a significant role in effort perception. It is now imperative for future research (a) to investigate the precise mechanisms underlying the interactions between the efference copy and reafferent spindle signals in the generation of effort perception, and (b) to explore the potential for altering spindle sensitivity to affect perceived effort during ecological physical exercise and, subsequently, influence physical activity behaviours.
image
Eco-Technoeconomic Analyses of Natural Gas-Powered SOFC/GT Hybrid Plants Accounting for Long-Term Degradation Effects Via Pseudo-Steady-State Model Simulations
Authors: Lai Haoxiang , Adams Thomas A. 
Published: June 2023

Abstract
In this study, four solid oxide fuel cell (SOFC) power plants, with natural gas (NG) as the fuel source, that account for long-term degradation were designed and simulated. The four candidate SOFC plants included a standalone SOFC plant, a standalone SOFC plant with a steam bottoming cycle, an SOFC/ (gas turbine) GT hybrid plant, and an SOFC/GT hybrid plant with a steam bottoming cycle. To capture dynamic behaviors caused by long-term SOFC degradation, this study employed a pseudo-stead-state approach that integrated real-time dynamic 1D SOFC models (degradation calculation embedded) with steady-state balance-of-plant models. Model simulations and eco-techno-economic analyses were performed over a 30-year plant lifetime using matlab simulink R2017a, aspen plus V12.1, and python 3.7.4. The results revealed that, while the standalone SOFC plant with a steam bottoming cycle provided the highest overall plant efficiency (65.0% LHV), it also had high SOFC replacement costs due to fast degradation. Instead, the SOFC/GT hybrid plant with a steam bottoming cycle was determined to be the best option, as it had the lowest levelized cost of electricity ($US 35.1/MWh) and the lowest cost of CO2 avoided (−$US100/ton CO2e).
Vibration Analysis Approach to Model Incremental Wear and Associated Sound in Multi-Contact Sliding Friction Mechanisms
Authors: Basit Kanza , Shams Hamza , Khan Muhammad Ali , Mansoor Asif 
Published: June 2023

Abstract
This paper proposes a simplistic approach toward estimating incremental wear in a multi-contact scenario using a vibrational analysis approach and in turn goes a step forward to model its associated sound. Predicted wear depth and frictional sound are compared to the experimental values obtained using a standardized pin-on-disc tribometer setup affixed with a free-field microphone to capture air-borne noise. The results show good conformity between the proposed analytical model values and the standardized experiments, hence ensuing that within certain limitations, the proposed model and the intended approach can effectively be used as a good estimator of wear and its sound in a multi-contact scenario.
No Associations Between Physical Activity and Immunogenicity in SARS-CoV-2 Seropositive Patients With Autoimmune Rheumatic Diseases Prior to and After Vaccination
Authors: Smaira Fabiana Infante , Mazzolani Bruna Caruso , Lemes Ítalo Ribeiro , da Silva Rafael Pires , Pinto Ana J. , Sieczkowska Sofia M. , Aikawa Nadia E. , Pasoto Sandra G. , Medeiros-Ribeiro Ana C. , Saad Carla G.S. , Yuk Emily F.N. , Silva Clovis A. , Swinton Paul , Kupa Leonard de Vinci Kanda , Hallal Pedro C. , Roschel Hamilton , Gualano Bruno , Bonfa Eloisa 
Published: June 2023

Aim: To investigate the association between physical activity and immunogenicity among SARS-CoV-2 seropositive patients with autoimmune rheumatic diseases prior to and following a 2-dose schedule of CoronaVac (Sinovac inactivated vaccine). Methods: This was a prospective cohort study within an open-label, single-arm, phase 4 vaccination trial conducted in Sao Paulo, Brazil. In this substudy, only SARS-CoV-2 seropositive patients were included. Immunogenicity was assessed by seroconversion rates of total anti-SARS-CoV-2 S1/S2 immunoglobulin G (IgG), geometric mean titers of anti-S1/S2 IgG, frequency of positive neutralizing antibodies, and neutralizing activity before and after vaccination. Physical activity was assessed through a questionnaire. Model-based analyses were performed controlling for age (<60 or ≥60 y), sex, body mass index (<25, 25–30, and >30 kg/m2), and use of prednisone, immunosuppressants, and biologics. Results: A total of 180 seropositive autoimmune rheumatic disease patients were included. There was no association between physical activity and immunogenicity before and after vaccination. Conclusions: This study suggests that the positive association between physical activity and greater antibody responses seen in immunocompromised individuals following vaccination is overridden by previous SARS-CoV-2 infection, and does not extend to natural immunity.
Emotional work of getting help: a qualitative analysis of caregiver-perceived barriers to responding to childhood adversity
Authors: Loveday Sarah , Balgovind Manisha , Hall Tess , Goldfeld Sharon , Sanci Lena , Hiscock Harriet 
Published: June 2023

ObjectiveTo explore caregivers’ experiences and challenges of accessing help for adversity across both health and social care sectors.DesignQualitative study design using semistructured interviews to explore how caregivers accessed services across health and social care. Interviews were audio recorded, transcribed verbatim and analysed using reflexive thematic analysis.SettingFamilies living in the city of Wyndham, Victoria, Australia.Participants17 caregivers of children aged 0–8 years.ResultsFive main themes emerged. (1) Emotional work of getting help. Caregivers described that getting help for life challenges was both emotionally taxing and effortful. (2) Trusting relationships are key. Engagement was related to the degree of relational practice and whether they felt judged or demeaned. (3) Wanting to manage on your own. There was a strong desire by caregivers to be independent and to only seek help when it was absolutely necessary. (4) Importance of knowing help was available and how to access it. (5) Overcoming service access barriers including long waiting times, restricted service criteria, transport issues and out-of-pocket expenses.ConclusionsCaregivers highlighted a multitude of barriers to getting help for life challenges. Addressing these barriers will require services to become more flexible and codesign best approaches with families in ongoing partnership. Improving community knowledge of available services and building trusting relationships is the first step to overcoming these barriers.
Myopic maculopathy among Chinese children with high myopia and its association with choroidal and retinal changes: the SCALE-HM study
Authors: Deng Junjie , Xu Xian , Pan Chen-Wei , Wang Jingjing , He Mingguang , Zhang Bo , Yang Jinliuxing , Hou Xiao-Wen , Zhu Zhuoting , Borchert Grace , Chen Jun , Cheng Tianyu , Yu Suqing , Fan Ying , Liu Kun , Zou Haidong , Xu Xun , He Xiangui 
Published: June 2023

AimsTo investigate myopic maculopathy in Chinese children with high myopia and its association with choroidal and retinal changes.MethodsThis cross-sectional study included Chinese children aged 4–18 years with high myopia. Myopic maculopathy was classified by fundus photography and retinal thickness (RT) and choroidal thickness (ChT) in the posterior pole were measured by swept-source optical coherence tomography. A receiver operation curve was used to determine the efficacy of fundus factors in classifying myopic maculopathy.ResultsIn total, 579 children aged 12.8±3.2 years with a mean spherical equivalent of −8.44±2.20 D were included. The proportions of tessellated fundus and diffuse chorioretinal atrophy were 43.52% (N=252) and 8.64% (N=50), respectively. Tessellated fundus was associated with a thinner macular ChT (OR=0.968, 95% CI: 0.961 to 0.975, p<0.001) and RT (OR=0.977, 95% CI: 0.959 to 0.996, p=0.016), longer axial length (OR=1.545, 95% CI: 1.198 to 1.991, p=0.001) and older age (OR=1.134, 95% CI: 1.047 to 1.228, p=0.002) and less associated with male children (OR=0.564, 95% CI: 0.348 to 0.914, p=0.020). Only a thinner macular ChT (OR=0.942, 95% CI: 0.926 to 0.959, p<0.001) was independently associated with diffuse chorioretinal atrophy. When using nasal macular ChT for classifying myopic maculopathy, the optimal cut-off value was 129.00 µm (area under the curve (AUC)=0.801) and 83.85 µm (AUC=0.910) for tessellated fundus and diffuse chorioretinal atrophy, respectively.ConclusionA large proportion of highly myopic Chinese children suffer from myopic maculopathy. Nasal macular ChT may serve as a useful index for classifying and assessing paediatric myopic maculopathy.Trial registration numberNCT03666052.
Trends and symptoms of SARS-CoV-2 infection: a longitudinal study on an Alpine population representative sample
Authors: Barbieri Giulia , Pizzato Massimo , Gögele Martin , Giardiello Daniele , Weichenberger Christian X , Foco Luisa , Bottigliengo Daniele , Bertelli Cinzia , Barin Laura , Lundin Rebecca , Pramstaller Peter P , Pattaro Cristian , Melotti Roberto 
Published: June 2023

ObjectivesThe continuous monitoring of SARS-CoV-2 infection waves and the emergence of novel pathogens pose a challenge for effective public health surveillance strategies based on diagnostics. Longitudinal population representative studies on incident events and symptoms of SARS-CoV-2 infection are scarce. We aimed at describing the evolution of the COVID-19 pandemic during 2020 and 2021 through regular monitoring of self-reported symptoms in an Alpine community sample.DesignTo this purpose, we designed a longitudinal population representative study, the Cooperative Health Research in South Tyrol COVID-19 study.Participants and outcome measuresA sample of 845 participants was retrospectively investigated for active and past infections with swab and blood tests, by August 2020, allowing adjusted cumulative incidence estimation. Of them, 700 participants without previous infection or vaccination were followed up monthly until July 2021 for first-time infection and symptom self-reporting: COVID-19 anamnesis, social contacts, lifestyle and sociodemographic data were assessed remotely through digital questionnaires. Temporal symptom trajectories and infection rates were modelled through longitudinal clustering and dynamic correlation analysis. Negative binomial regression and random forest analysis assessed the relative importance of symptoms.ResultsAt baseline, the cumulative incidence of SARS-CoV-2 infection was 1.10% (95% CI 0.51%, 2.10%). Symptom trajectories mimicked both self-reported and confirmed cases of incident infections. Cluster analysis identified two groups of high-frequency and low-frequency symptoms. Symptoms like fever and loss of smell fell in the low-frequency cluster. Symptoms most discriminative of test positivity (loss of smell, fatigue and joint-muscle aches) confirmed prior evidence.ConclusionsRegular symptom tracking from population representative samples is an effective screening tool auxiliary to laboratory diagnostics for novel pathogens at critical times, as manifested in this study of COVID-19 patterns. Integrated surveillance systems might benefit from more direct involvement of citizens’ active symptom tracking.