bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of emotional arousal on visual attentional performance: a systematic review
Authors: Zsidó Andras N. 
Published: July 2023

AbstractAlthough the arousal elicited by emotional stimuli, similarly to valence, is an integrative part of emotion theories, previous studies and reviews mostly focused on the valence of a stimulus and rarely investigated the role of arousal. Here, I systematically searched for articles that used visual attentional paradigms, manipulated emotional arousal by auditory or visual, task-relevant or task-irrelevant stimuli, measured behavioral responses, ocular behavior, or neural correlates. I found that task-relevant arousing stimuli draw and hold attention regardless of the modality. In contrast, task-irrelevant arousing stimuli impaired task performance. However, when the emotional content precedes the task or it is presented for a longer duration, arousal increased performance. Future directions on how research could address the remaining questions are discussed.
Coalition-based task assignment with priority-aware fairness in spatial crowdsourcing
Authors: Zhao Yan , Zheng Kai , Wang Ziwei , Deng Liwei , Yang Bin , Pedersen Torben Bach , Jensen Christian S. , Zhou Xiaofang 
Published: July 2023

AbstractWith the widespread use of networked and geo-positioned mobile devices, e.g., smartphones, Spatial Crowdsourcing (SC), which refers to the assignment of location-based tasks to moving workers, is drawing increasing attention. One of the critical issues in SC is task assignment that allocates tasks to appropriate workers. We propose and study a novel SC problem, namely Coalition-based Task Assignment (CTA), where the spatial tasks (e.g., home improvement and furniture installation) may require more than one worker (forming a coalition) to cooperate to maximize the overall rewards of workers. We design a greedy and an equilibrium-based CTA approach. The greedy approach forms a set of worker coalitions greedily for performing tasks and uses an acceptance probability to identify high-value task assignments. In the equilibrium-based approach, workers form coalitions in sequence and update their strategies (i.e., selecting a best-response task), to maximize their own utility (i.e., the reward of the coalition they belong to) until a Nash equilibrium is reached. Since the equilibrium obtained is not unique and optimal in terms of total rewards, we further propose a simulated annealing scheme to find a better Nash equilibrium. To achieve fair task assignments, we optimize the framework to distribute rewards fairly among workers in a coalition based on their marginal contributions and give workers who arrive first at the SC platform highest priority. Extensive experiments demonstrate the efficiency and effectiveness of the proposed methods on real and synthetic data.
Withdrawal of mechanical ventilation in amyotrophic lateral sclerosis patients: a multicenter Italian survey
Authors: Moglia Cristina , Palumbo Francesca , Veronese Simone ,   M. N. D. Italian Study Group, Angelocola Stefania , Barone Paolo , Bartolomei Ilaria , Bersano Enrica , Bombaci Alessandro , Borghero Giuseppe , Cabras Sara , Cambieri Chiara , Canali Elena , Canosa Antonio , Capasso Margherita , Caponnetto Claudia , Cardinali Patrizio , Casmiro Mario , Ceccanti Marco , Chiò Adriano , Consonni Monica , Dalla Bella Eleonora , De Marchi Fabiola , De Mattei Filippo , D’Errico Eustachio , Di Pede Francesca , Diamanti Luca , Dubbioso Raffaele , Filippi Massimo , Filosto Massimiliano , Fini Nicola , Gianferrari Giulia , Grassano Maurizio , Inghilleri Maurizio , La Bella Vincenzo , Lauria Pinter Giuseppe , Libonati Laura , Logullo Francesco , Mandrioli Jessica , Manera Umberto , Martinelli Ilaria , Martusciello Gioacchino , Matà Sabrina , Matteoni Enrico , Mazzini Letizia , Medici Doriana , Miniello Stefania , Moret Federica , Nozzoli Cecilia , Piccirillo Giovanni , Pilurzi Giovanna , Riva Nilo , Romito Silvia , Russo Massimo , Salvi Fabrizio , Sette Elisabetta , Silani Vincenzo , Simone Isabella Laura , Simonini Cecilia , Spataro Rossella , Squintani Giovanna , Stano Salvatore , Tanel Raffaella , Tedeschi Gioacchino , Ticozzi Nicola , Toriello Antonella , Tremolizzo Lucio , Trojsi Francesca , Vacchiano Veria , Vasta Rosario , Volanti Paolo , Zinno Lucia , Zucchi Elisabetta , Calvo Andrea 
Published: July 2023

Abstract
Background
Law 219/2017 was approved in Italy in December
2017, after a years-long debate on the autonomy of healthcare choices. This Law, for the first time in Italian legislation, guarantees the patient’s right to request for withdrawal of life-sustaining treatments, including mechanical ventilation (MV).

Objective
To investigate the current status of MV withdrawal in amyotrophic lateral sclerosis (ALS) patients in Italy and to assess the impact of Law 219/2017 on this practice.

Methods
We conducted a Web-based survey, addressed to Italian neurologists with expertise in ALS care, and members of the Motor Neuron Disease Study Group of the Italian Society of Neurology.

Results
Out of 40 ALS Italian centers, 34 (85.0%) responded to the survey. Law 219/2017 was followed by an increasing trend in MV withdrawals, and a significant increase of neurologists involved in this procedure (p 0.004). However, variations across Italian ALS centers were observed, regarding the inconsistent involvement of community health services and palliative care (PC) services, and the intervention and composition of the multidisciplinary team.

Conclusions
Law 219/2017 has had a positive impact on the practice of MV withdrawal in ALS patients in Italy. The recent growing public attention on end-of-life care choices, along with the cultural and social changes in Italy, requires further regulatory frameworks that strengthen tools for self-determination, increased investment of resources in community and PC health services, and practical recommendations and guidelines for health workers involved.
Postfire hydrologic response along the Central California (USA) coast: insights for the emergency assessment of postfire debris-flow hazards
Authors: Thomas Matthew A. , Kean Jason W. , McCoy Scott W. , Lindsay Donald N. , Kostelnik Jaime , Cavagnaro David B. , Rengers Francis K. , East Amy E. , Schwartz Jonathan Y. , Smith Douglas P. , Collins Brian D. 
Published: July 2023

AbstractThe steep, tectonically active terrain along the Central California (USA) coast is well known to produce deadly and destructive debris flows. However, the extent to which fire affects debris-flow susceptibility in this region is an open question. We documented the occurrence of postfire debris floods and flows following the landfall of a storm that delivered intense rainfall across multiple burn areas. We used this inventory to evaluate the predictive performance of the US Geological Survey M1 likelihood model, a tool that presently underlies the emergency assessment of postfire debris-flow hazards in the western USA. To test model performance, we used the threat score skill statistic and found that the rainfall thresholds estimated by the M1 model for the Central California coast performed similarly to training (Southern California) and testing (Intermountain West) data associated with the original model calibration. Model performance decreased when differentiating between “minor” and “major” postfire hydrologic response types, which weigh effects on human life and infrastructure. Our results underscore that the problem of false positives is a major challenge for developing accurate rainfall thresholds for the occurrence of postfire debris flows. As wildfire activity increases throughout the western USA, so too will the demand for the assessment of postfire debris-flow hazards. We conclude that additional collection of field-verified inventories of postfire hydrologic response will be critical to prioritize which model variables may be suitable candidates for regional calibration or replacement.
Clean versus dirty electricity generation and economic growth in South Africa: time–frequency study
Authors: Phiri Andrew , Nyoni Bothwell 
Published: July 2023

AbstractThe purpose of the study is to contrast the impact of ‘clean’ and ‘dirty’ electricity production on economic growth for South Africa and determine whether a faster transition from fossil fuels to renewables is beneficial for growth. To this end, we use wavelet coherence analysis to examine the time–frequency relationship between electricity and economic growth for aggregated and disaggregated measures of clean and dirty sources over the period 1985–2021 At an aggregated level, the low frequency (long-run) correlations are eventually substituted with high frequency (short-run) co-movements. At disaggregated level, the results are mixed, with dirty energy components (coal, oil, gas) having a weakening effect on economic growth over time whilst clean energy sources (solar and wind, biomass, hydro) show the greatest potential for growth over both low and high frequency relationships. Moreover, the various structural breaks identified in the frequency bands for different electricity sources allow us to evaluate the impact of energy policies and load shedding on the electricity-growth relationship and offer further insights to which clean sources of electricity production have more potential to be growth enhancing.
From Thieves to Martyrs: The Story of Two Jews from Early Modern Moravia
Authors: Cohen Roman Oren , Soukup Daniel 
Published: July 2023

AbstractThis paper focuses on the story of two Jewish men who were convicted of theft and executed in Prostějov, Moravia, in the spring of 1684. Although the two were offered a pardon in exchange for converting to Christianity, they resolutely refused. Their story was recorded in a contemporaneous Yiddish song that serves as the basis for the current case-study. The informative layer of the text portrays an event that can be contextualized within the campaign to proselytize Jews in the Bohemian lands at the turn of the seventeenth and eighteenth centuries. Likewise, it indicates the great significance that Jews and Christians alike attributed to public conversions—or the lack thereof. From the formative perspective, the text crowns the two Jews as martyrs who died sanctifying God’s Name, disregarding their undenied legal culpability. Accordingly, this paper traces developments in the Ashkenazic ethos of martyrdom from the Middle Ages to the seventeenth century. It also highlights the shared cultural legacy that bound the larger early modern Ashkenazic communities, such as those in Amsterdam, Hamburg, Frankfurt, or Prague, to smaller Jewish settlements, like those of Moravia. Besides its hagiographical function, this historic song also imparts didactic and moralizing messages. It censures those who are too lenient vis-à-vis their children’s education as well as criticizing the habit of gambling, practices that may lead to criminal activities and push those involved to the margins of Jewish society.
Noncoding RNAs in atherosclerosis: regulation and therapeutic potential
Authors: Qi Luyao , Xing Jixiang , Yuan Yuesong , Lei Ming 
Published: July 2023

AbstractAtherosclerosis, a chronic disease of arteries, results in high mortality worldwide as the leading cause of cardiovascular disease. The development of clinically relevant atherosclerosis involves the dysfunction of endothelial cells and vascular smooth muscle cells. A large amount of evidence indicates that noncoding RNAs, such as microRNAs (miRNAs), long noncoding RNAs (lncRNAs), and circular RNAs (circRNAs), are involved in various physiological and pathological processes. Recently, noncoding RNAs were identified as key regulators in the development of atherosclerosis, including the dysfunction of endothelial cells, and vascular smooth muscle cells and it is pertinent to understand the potential function of noncoding RNAs in atherosclerosis development. In this review, the latest available research relates to the regulatory role of noncoding RNAs in the progression of atherosclerosis and the therapeutic potential for atherosclerosis is summarized. This review aims to provide a comprehensive overview of the regulatory and interventional roles of ncRNAs in atherosclerosis and to inspire new insights for the prevention and treatment of this disease.
The impact of green financial development on stock price crash risk from the perspective of information asymmetry in Chinese listed companies
Authors: Zhang Zhibin , Ding Youqiang 
Published: July 2023

AbstractSolving the crash risk problem of corporate stock price caused by information asymmetry can mitigate the negative externality of its carbon emission to become green, low-carbon, and high-quality development. Green finance generally profoundly impacts micro-corporate economics and macro-financial systems but remains a giant puzzle of whether they can effectively resolve the crash risk. This paper examined the impact of green financial development on the stock price crash risk using the sample data of non-financial listed companies in Shanghai and Shenzhen A stock market in China from 2009 to 2020. We found that green financial development significantly inhibits the stock price crash risk; this is more obvious in listed companies with a high level of asymmetric information. And companies in high-level regions of green financial development attracted more attention from institutional investors and analysts. As a result, they disclosed more information about their operational status, thus reducing the crash risk of corporate stock price from the torrential public pressure of lousy environmental details. Therefore, this study will help continuously discuss the costs, benefits, and value promotion of green finance for synergy between corporate performance and environmental performance to improve ESG capabilities.
Standing and Pre-trial Misconduct: Hypocrisy, ‘Separation’, Inconsistent Blame, and Frustration
Authors: Stark Findlay 
Published: July 2023

AbstractExisting justifications for exclusionary rules and stays of proceedings in response to pre-trial wrongdoing by police officers and prosecutors are often thought to be counter-productive or disproportionate in their consequences. This article begins to explore whether the concept of standing to blame can provide a fresh justification for such responses. It focuses on a vice related to standing—hypocrisy—and a related vice concerning inconsistent blame. It takes seriously the point that criminal justice agencies, although all part of the State, are in real terms separated from each other, and analyses the so-called separation thesis (or theses). It concludes that hypocrisy and inconsistent blame arguments could plausibly justify exclusion and stays only in relation to lower-level offending, and even there only indirectly. This is in the sense that exclusion and stays are expressions of judicial frustration with other bodies for their failure to take pre-trial wrongdoing seriously.
Lessons Learned from Telemonitoring in an Outpatient Bariatric Surgery Pathway—Secondary Outcomes of a Patient Preference Clinical Trial
Authors: van Ede Elisabeth S. , Scheerhoorn Jai , Schonck Friso M. J. F. , van der Stam Jonna A. , Buise Marc P. , Nienhuijs Simon W. , Bouwman R. Arthur 
Published: July 2023

Abstract
Background
Remote monitoring is increasingly used to support postoperative care. This study aimed to describe the lessons learned from the use of telemonitoring in an outpatient bariatric surgery pathway.

Materials and Methods
Patients were assigned based on their preference to an intervention cohort of same-day discharge after bariatric surgery. In total, 102 patients were monitored continuously for 7 days using a wearable monitoring device with a Continuous and Remote Early Warning Score–based notification protocol (CREWS). Outcome measures included missing data, course of postoperative heart and respiration rate, false positive notification and specificity analysis, and vital sign assessment during teleconsultation.

Results
In 14.7% of the patients, data for heart rate was missing for > 8 h. A day-night-rhythm of heart rate and respiration rate reappeared on average on postoperative day 2 with heart rate amplitude increasing after day 3. CREWS notification had a specificity of 98%. Of the 17 notifications, 70% was false positive. Half of them occurred between day 4 and 7 and were accompanied with surrounding reassuring values. Comparable postoperative complaints were encountered between patients with normal and deviated data.

Conclusion
Telemonitoring after outpatient bariatric surgery is feasible. It supports clinical decisions, however does not replace nurse or physician care. Although infrequent, the false notification rate was high. We suggested additional contact may not be necessary when notifications occur after restoration of circadian rhythm or when surrounding reassuring vital signs are present. CREWS supports ruling out serious complications, what may reduce in-hospital re-evaluations. Following these lessons learned, increased patients’ comfort and decreased clinical workload could be expected.

Trial Registration
ClinicalTrials.gov. Identifier: NCT04754893.

Graphical Abstract
A cost estimation approach for aircraft design enhancement
Authors: Abbate Raffaele , Turino Maria Antonietta , Morse Llewellyn , Fera Marcello , Mallardo Vincenzo , Macchiaroli Roberto 
Published: July 2023

AbstractThis paper presents a novel reliability-based parametric methodology for quantifying the reliability of cost estimates for new composite aircraft components. In recent years, the aircraft production sector has increased its attention on optimizing their composite manufacturing operations. It has become clear that a key factor in the success of these operations is the consideration that not only technical factors, but also economic ones as well are relevant. Composite manufacturing variability is greatly influenced by many of these factors, and since manufacturing with composites is significantly more difficult than with more traditional materials, there are many sources of uncertainty that could influence the reliability of manufacturing cost estimates for new composite aircraft components. Therefore, it is worth considering these sources of uncertainty during the cost estimation process and to quantify the reliability of the cost estimates. To demonstrate the proposed methodology, a numerical example featuring a real-life composite aircraft component from a Boeing 787, with real-life data, is presented. Results show that the proposed methodology can quantify the uncertainty associated with cost estimates for new composite aircraft components in an effective manner, thereby supporting engineers in optimising the cost of their designs, helping them avoid errors in budget definition, and enabling them to allocate resources more efficiently.
Blockchain for Data Originality in Pharma Manufacturing
Authors: Durá Marta , Leal Fátima , Sánchez-García Ángel , Sáez Carlos , García-Gómez Juan M. , Chis Adriana E. , González-Vélez Horacio 
Published: July 2023

Abstract
Purpose
This paper analyses the feasibility of tracking data originality for pharmaceutical manufacturing in a tamper-proof manner using a geographically distributed system. The main research question is whether it is possible to ensure the traceability of drug manufacturing through the use of smart contracts and a private blockchain network.

Methods
This work employs a private Ethereum network with a proof-of-authority consensus algorithm to allow participating nodes to commit the medicament manufacturing originality as transactions in blocks. We use smart contracts to assess the “Original” principle of the ALCOA+ data integrity principles for full sensor-enabled production lines within pharmaceutical manufacturing plants. We have evaluated our data originality assessment approach employing a temporal series of 1300 reports generated based on real datasets from pharma production lines. Out of these reports, 300 reports have been randomly tampered with to make them “unoriginal” (i.e., falsified).

Results
Evaluation consistently shows that the proposed approach systematically detects all the manufacturing records whether original or not, together with any source of falsification. By randomly injecting four common data falsification types, their approach effectively detects tampering and ensures the authenticity of the data originality acquired by sensors within manufacturing lines.

Conclusion
The approach of using a private blockchain network with a proof-of-authority consensus algorithm and smart contracts is a feasible method to track data originality for pharmaceutical manufacturing in a tamper-proof manner. In addition, this approach effectively detects tampering and ensures the authenticity of the data originality acquired by sensors within manufacturing lines.
A Systematic Analysis of the Clinical Outcome Associated with Multiple Reclassified Desmosomal Gene Variants in Arrhythmogenic Right Ventricular Cardiomyopathy Patients
Authors: Nagyova Emilia , Hoorntje Edgar T. , te Rijdt Wouter P. , Bosman Laurens P. , Syrris Petros , Protonotarios Alexandros , Elliott Perry M. , Tsatsopoulou Adalena , Mestroni Luisa , Taylor Matthew R. G. , Sinagra Gianfranco , Merlo Marco , Wada Yuko , Horie Minoru , Mogensen Jens , Christensen Alex H. , Gerull Brenda , Song Lei , Yao Yan , Fan Siyang , Saguner Ardan M. , Duru Firat , Koskenvuo Juha W. , Cruz Marino Tania , Tichnell Crystal , Judge Daniel P. , Dooijes Dennis , Lekanne Deprez Ronald H. , Basso Cristina , Pilichou Kalliopi , Bauce Barbara , Wilde Arthur A. M. , Charron Philippe , Fressart Véronique , van der Heijden Jeroen F. , van den Berg Maarten P. , Asselbergs Folkert W. , James Cynthia A. , Jongbloed Jan D. H. , Harakalova Magdalena , van Tintelen J. Peter 
Published: July 2023

Abstract
The presence of multiple pathogenic variants in desmosomal genes (DSC2, DSG2, DSP, JUP, and PKP2) in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) has been linked to a severe phenotype. However, the pathogenicity of variants is reclassified frequently, which may result in a changed clinical risk prediction. Here, we present the collection, reclassification, and clinical outcome correlation for the largest series of ARVC patients carrying multiple desmosomal pathogenic variants to date (n = 331). After reclassification, only 29% of patients remained carriers of two (likely) pathogenic variants. They reached the composite endpoint (ventricular arrhythmias, heart failure, and death) significantly earlier than patients with one or no remaining reclassified variant (hazard ratios of 1.9 and 1.8, respectively). Periodic reclassification of variants contributes to more accurate risk stratification and subsequent clinical management strategy.
Feasibility study for the manufacturing of hybrid pinion shafts with the cross-wedge rolling process
Authors: Merkel Paulina , Budde Laura , Grajczak Jan , Nowroth Christian , Prasanthan Vannila , Kriwall Mareile , Lammers Marius , Nothdurft Sarah , Hermsdorf Jörg , Twiefel Jens , Overmeyer Ludger , Kaierle Stefan , Wallaschek Jörg , Breidenstein Bernd , Behrens Bernd-Arno , Stonis Malte 
Published: July 2023

AbstractThe Collaborative Research Center 1153 is investigating an innovative process chain for the production of hybrid components. The hybrid workpieces are first joined and then formed by cross-wedge rolling. Pinion shafts were manufactured to investigate the behavior of the joining zone under increased complexity of the forming process. For this purpose, six types of workpieces produced by three types of joining processes were formed into pinion shafts. The reference process provides a shaft with a smooth bearing seat. It was found that the increased complexity did not present any challenges compared to the reference processes. A near-net shape geometry was achieved for the pinions made of steel.