bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intravesical textiloma mistook for bladder stone: A case report
Authors: Thomas Jonaviva Anthony , Ngowi Bartholomeo Nicholaus , Mpelumbe Janeth , Mwasakialo Gideon , Mbwambo Jasper Saidi , Bogdanowicz Jack , Bright Frank , Kien Mteta Alfred , Mbwambo Orgeness Jasper 
Published: June 2023

Key Clinical MessageIntravesical textiloma is a rare surgical complication, that may cause nonspecific lower urinary tract symptoms. Clinicians should consider it in patients with a history of bladder surgery and persistent or new‐onset urinary symptoms.AbstractIntravesical textiloma is a rare condition usually presents asymptomatic or with non specific symptoms. A 72 years old man with prior open prostatectomy presented lower urinary tract symptoms and diagnosed with bladder stones, explorative laparotomy revealed semi calcified gauze. Similar history should prompt suspicion of this condition.
Guillain‐Barré syndrome following COVID‐19 vaccination: An updated systematic review of cases
Authors: Shaheen Nour , Ramadan Abdelraouf , Nashwan Abdulqadir J. , Shaheen Ahmed , Ahmad Shahzaib , Motawea Karam R. , Mohamed Salaheldin , Mohamed Rahma Sameh , Swed Sarya , Aiash Hani 
Published: June 2023

Key Clinical MessageGuillain‐Barré syndrome (GBS) is a rare but possible complication that may occur after COVID‐19 vaccination. In this systematic review, we found that GBS presented in patients with an average age of 58. The average time for symptoms to appear was 14.4 days. Health care providers should be aware of this potential complication.AbstractMost instances of Guillain‐Barré syndrome (GBS) are caused by immunological stimulation and are discovered after vaccinations for tetanus toxoid, oral polio, and swine influenza. In this systematic study, we investigated at GBS cases that were reported after receiving the COVID‐19 vaccination. Based on PRISMA guidelines, we searched five databases (PubMed, Google Scholar, Ovid, Web of Science, and Scopus databases) for studies on COVID‐19 vaccination and GBS on August 7, 2021. To conduct our analysis, we divided the GBS variants into two groups, acute inflammatory demyelinating polyneuropathy and non‐acute inflammatory demyelinating polyneuropathy (AIDP and non‐AIDP), and compared the two groups with mEGOS and other clinical presentation In this systematic review, 29 cases were included in 14 studies. Ten cases belonged to the AIDP variant, 17 were non‐AIDP (one case had the MFS variant, one AMAN variant, and 15 cases had the BFP variant), and the two remaining cases were not mentioned. Following COVID‐19 vaccination, GBS cases were, on average, 58 years of age. The average time it took for GBS symptoms to appear was 14.4 days. About 56 percent of the cases (56%) were classified as Brighton Level 1 or 2, which defines the highest level of diagnostic certainty for patients with GBS. This systematic review reports 29 cases of GBS following COVID‐19 vaccination, particularly those following the AstraZeneca/Oxford vaccine. Further research is needed to assess all COVID‐19 vaccines' side effects, including GBS.
A case report of atypical preeclampsia with severity criteria for hydatidiform complete mole
Authors: Pérez‐Nieto Orlando Rubén , Herrera‐Venegas Christian Alberto , Pozos‐Cortés Karen Pamela , Flores‐Ramírez Raymundo , Ugalde‐Real Jesús Salvador , Argüello‐Bolaños Jardiel , Puente Marian Elizabeth Phinder , Zamarrón‐López Éder Iván , Deloya‐Tomas Ernesto 
Published: June 2023

Key Clinical MassagePreeclampsia is defined as elevation of blood pressure and any of the following severity criteria: proteinuria, thrombocytopenia, elevation of creatinine in the absence of another renal pathology, elevation of transaminases, pulmonary edema, or neurological symptoms. However, after 20 weeks of gestation in a previously normotensive patient, cases of preeclampsia associated with molar pregnancy have been described in patients at less than 20 weeks of gestation. A 26‐year‐old woman, at 14.1 weeks of gestation was admitted to the lower extremities with facial edema, holocranial headache, nausea, epigastralgia, phosphenes, and photophobia, with a double‐length uterine fundus for gestational age and ultrasonography. Obstetricians who showed images of snowflakes without fetuses and annexes had multiple thecal‐lutein cysts. Atypical preeclampsia was identified using the severity data for complete hydatidiform moles. Given the possibility of serious complications that may endanger the life of the maternal–fetal binomial, atypical forms of preeclampsia should be suspected.
Career counselors’ experiential reflections on early recollections in career construction counseling
Authors: Dalene Kirsten Marie 
Published: June 2023

AbstractMany studies validate career construction counseling (CCC); however, counselors’ experiences of using early recollections (ERs) in CCC have garnered little research attention. Preliminary research among career counselors in Norway has revealed skepticism about using ERs, owing to aspects such as associations with therapy. Therefore, this study examines career counselors’ experiential reflections on using ERs in CCC. Through thematic analysis of multistage focus group interviews from action research with 16 career counselors, their experiential reflections on using ERs in CCC were identified. Necessary awareness for using ERs in CCC is discussed, and the study indicates career counselors’ raised awareness regarding role understanding and a need for promoting career counselors’ emotional and narrative competences. A dual training process is suggested, combining being counseled using CCC with both theoretical and practical training along with a professional community for reflections. Practical implications and limitations are discussed, and directions for future research are suggested.
Effect of pretreatment of root dentin surface with cold atmospheric plasma on improving the bond strength of fiber post and resin cement: In vitro study
Authors: Manouchehri Neshatafarin , Ghodsi Safoura , Atri Faezeh , Sarraf Pegah , Seyedi Dorsa , Valizadeh Sara 
Published: June 2023

AbstractIntroductionAchieving stable adhesion between fiber post and interradicular dentin is a challenging process in the restoration of endodontically treated teeth. This study was conducted to investigate the effect of surface pretreatment with cold atmospheric plasma (CAP) on improving the bond strength between them.Materials and methodsForty‐eight single‐canal mandibular premolars were cut 1 mm above the cementoenamel junction to keep the root length of 14 mm or more. After endodontic treatment and preparation of the post space, the teeth were divided into four groups regarding the pretreatment of dentin surfaces, including normal saline, ethylenediaminetetraacetic acid (EDTA), CAP, and CAP + EDTA groups. The data were analyzed using paired and independent t‐test and one‐way analysis of variance and the significance level was set at p < .05.ResultsThe bond strength was significantly higher in the coronal third than in the apical third in all the groups. Moreover, the bond strength was significantly higher in the CAP + EDTA‐treated group. The bond strength increased significantly in the CAP group compared to the normal saline group. In addition, the bond strength increased significantly in the CAP or EDTA groups compared to the control group. The lowest bond strength belonged to the control group (normal saline).ConclusionThe surface pretreatment with CAP (alone or in combination with EDTA) played a significant role in improving the bond strength of fiber post and root canal dentin.
Remotely operated robotic microscopy for rapid diagnosis of bronchoscopic cytology specimens
Authors: Naso Julia R. , Chan Jackie , Reisenauer Janani , Edell Eric S. , Stackhouse Katherine , Bungum Aaron O. , Vierkant Robert A. , Pierson Karlyn , Seidl Andrew , Sturgis Charles D. , Meroueh Chady , Huang Yajue , Hartley Christopher P. 
Published: June 2023

AbstractBackgroundObtaining a diagnosis and treating pulmonary malignancies during the same anesthesia requires either an on‐site pathologist or a system for remotely evaluating microscopic images. Cytology specimens are challenging to remotely assess given the need to navigate through dispersed and three‐dimensional cell clusters. Remote navigation is possible using robotic telepathology, but data are limited on the ease of use of current systems, particularly for pulmonary cytology.MethodsAir dried modified Wright‐Giemsa stained slides from 26 touch preparations of transbronchial biopsies and 27 smears of endobronchial ultrasound guided fine needle aspirations were scored for ease of adequacy assessment and ease of diagnosis on robotic (rmtConnect Microscope) and non‐robotic telecytology platforms. Diagnostic classifications were compared between glass slides and the robotic and non‐robotic telecytology assessments.ResultsCompared to non‐robotic telecytology, robotic telecytology had a greater ease of adequacy assessment and non‐inferior ease of diagnosis. The median time to diagnosis using robotic telecytology was 85 s (range 28–190 s). Diagnostic categories were concordant for 76% of cases in robotic versus non‐robotic telecytology and 78% of cases in robotic telecytology versus glass slide diagnosis. Weighted Cohen's kappa scores for agreement in these comparisons were 0.84 and 0.72, respectively.ConclusionsUse of a remote‐controlled robotic microscope improved the ease of adequacy assessment compared to non‐robotic telecytology and enabled strongly concordant diagnoses to be expediently rendered. This study provides evidence that modern robotic telecytology is a feasible and user‐friendly method of remotely and potentially intraoperatively rendering adequacy assessments and diagnoses on bronchoscopic cytology specimens.
Effectiveness of offloading interventions for people with diabetes‐related foot ulcers: A systematic review and meta‐analysis
Authors: Lazzarini P. A. , Armstrong D. G. , Crews R. T. , Gooday C. , Jarl G. , Kirketerp‐Moller K. , Viswanathan V. , Bus S. A. 
Published: June 2023

AbstractBackgroundOffloading treatment is crucial to heal diabetes‐related foot ulcers (DFU). This systematic review aimed to assess the effectiveness of offloading interventions for people with DFU.MethodsWe searched PubMed, EMBASE, Cochrane databases, and trials registries for all studies relating to offloading interventions in people with DFU to address 14 clinical question comparisons. Outcomes included ulcers healed, plantar pressure, weight‐bearing activity, adherence, new lesions, falls, infections, amputations, quality of life, costs, cost‐effectiveness, balance, and sustained healing. Included controlled studies were independently assessed for risk of bias and had key data extracted. Meta‐analyses were performed when outcome data from studies could be pooled. Evidence statements were developed using the GRADE approach when outcome data existed.ResultsFrom 19,923 studies screened, 194 eligible studies were identified (47 controlled, 147 non‐controlled), 35 meta‐analyses performed, and 128 evidence statements developed. We found non‐removable offloading devices likely increase ulcers healed compared to removable offloading devices (risk ratio [RR] 1.24, 95% CI 1.09–1.41; N = 14, n = 1083), and may increase adherence, cost‐effectiveness and decrease infections, but may increase new lesions. Removable knee‐high offloading devices may make little difference to ulcers healed compared to removable ankle‐high offloading devices (RR 1.00, 0.86–1.16; N = 6, n = 439), but may decrease plantar pressure and adherence. Any offloading device may increase ulcers healed (RR 1.39, 0.89–2.18; N = 5, n = 235) and cost‐effectiveness compared to therapeutic footwear and may decrease plantar pressure and infections. Digital flexor tenotomies with offloading devices likely increase ulcers healed (RR 2.43, 1.05–5.59; N = 1, n = 16) and sustained healing compared to devices alone, and may decrease plantar pressure and infections, but may increase new transfer lesions. Achilles tendon lengthening with offloading devices likely increase ulcers healed (RR 1.10, 0.97–1.27; N = 1, n = 64) and sustained healing compared to devices alone, but likely increase new heel ulcers.ConclusionsNon‐removable offloading devices are likely superior to all other offloading interventions to heal most plantar DFU. Digital flexor tenotomies and Achilles tendon lengthening in combination with offloading devices are likely superior for some specific plantar DFU locations. Otherwise, any offloading device is probably superior to therapeutic footwear and other non‐surgical offloading interventions to heal most plantar DFU. However, all these interventions have low‐to‐moderate certainty of evidence supporting their outcomes and more high‐quality trials are needed to improve our certainty for the effectiveness of most offloading interventions.
Comparative efficacy of growth factor therapy in healing diabetes‐related foot ulcers: A network meta‐analysis of randomized controlled trials
Authors: Thanigaimani Shivshankar , Jin Harry , Ahmad Usama , Anbalagan Raghuveeran , Golledge Jonathan 
Published: June 2023

AbstractIntroductionThis study examined the relative efficacy of growth factor therapies in healing diabetes‐related foot ulcers (DFU).MethodsPubMed and Cochrane databases were searched for randomized controlled trials testing growth factor therapies for treating DFU. The primary outcome was complete wound closure. Results were reported as relative risk (RR) ± 95% credible intervals (CrI). The risk of bias was assessed using Cochrane's RoB‐2 tool.ResultsA total of 31 RCTs involving 2174 participants were included. Only 13 of the trials (n = 924) reported on the aetiology of the ulcers (85.4% neuropathic and 14.6% ischaemic). Epidermal growth factor (RR 3.83; 95% CrI 1.81, 9.10), plasma‐rich protein (PRP) (RR 3.36; 95% CrI 1.66, 8.03) and platelet‐derived growth factor (PDGF) (RR 2.47; 95% CrI 1.23, 5.17) significantly improved the likelihood of complete ulcer healing compared to control. Sub‐analyses suggested that PRP (3 trials ‐ RR 9.69; 95% CrI 1.37, 103.37) and PDGF (6 trials ‐ RR 2.22; 95% CrI 1.12, 5.19) significantly improved the likelihood of wound closure amongst trial mainly recruiting participants with neuropathic ulcers. Eleven trials had a low risk of bias, 9 had some concerns and 11 had a high risk of bias. Sub‐analysis of trials with a low risk of bias suggested that none of the growth factors significantly improved ulcer healing compared with control.DiscussionThis network meta‐analysis found low‐quality evidence that Epidermal growth factor, PRP and PDGF therapy improved DFU healing likelihood compared with control. Larger well‐designed trials are needed.
Defense behavior of two closely related but geographically distant host species against cuckoo parasitism: A next test for the parallel coevolution
Authors: Trnka Alfréd , Ma Laikun , Yan Hanlin , Wang Longwu , Liang Wei 
Published: June 2023

AbstractInteractions between avian brood parasites, such as common cuckoos (Cuculus canorus), and their hosts are one of the best‐studied examples of the coevolutionary arms race. Different stages of this arms race can be seen in different races of common cuckoos and their hosts across their range. However, little is known whether selected populations of two closely related but geographically distant species with probably different coevolutionary histories with the common cuckoo are also at different stages of the arms race. In this study, we tested this prediction experimentally using the same non‐mimetic model eggs and three‐dimensional (3D) printed models of the gray adult common cuckoo (Cuculus canorus). We examined egg recognition and egg rejection and aggression against the common cuckoo in the great reed warbler (Acrocephalus arundinaceus) and Oriental reed warbler (Acrocephalus orientalis), in Slovakia of Europe and northeast China of Asia. The results showed that the great reed warbler exhibited stronger responses to experimental model eggs and 3D models of the common cuckoo than the Oriental reed warbler. We conclude that both the great reed warbler and Oriental reed warbler have well‐developed antiparasitic behaviors against common cuckoos in the studied populations, but with different levels of defense intensity, which may be due to local differences in parasitic pressure and the risk of parasitism. This provides an opportunity to study coevolutionary processes between the brood parasite and its hosts together in both species at large geographical scales.
Enabling robust environmental DNA assay design with “unikseq” for the identification of taxon‐specific regions within whole mitochondrial genomes
Authors: Allison Michael J. , Warren René L. , Lopez M. Louie , Acharya‐Patel Neha , Imbery Jacob J. , Coombe Lauren , Yang Cecilia L. , Birol Inanc , Helbing Caren C. 
Published: June 2023

AbstractEnvironmental DNA (eDNA) is revolutionizing species monitoring in nature. At the heart of any eDNA approach is the reliance upon sufficient DNA sequence information to satisfy the demands of eDNA assay specificity and sensitivity. The most common source of this information has been restricted to short barcoding regions of the mitochondrial genome (mitogenome) and marker genes. The use of these limited regions for assay design has often resulted in substantial trade‐offs in assay performance. With increased accessibility of full mitogenome assemblies, the potential for designing more robust eDNA assays is considerably enhanced. However, this also poses a new challenge to effectively identify suitable regions for assay design using considerably larger sequences. We present unikseq, a utility that uses words of length k (k‐mers) to identify unique regions in a reference sequence relative to tolerated (ingroup) and not‐tolerated (outgroup or non‐target) sequence sets, quickly and with low memory that can yield highly specific assays. We illustrate its application within an assay development workflow through use‐case examples for the design and validation of four quantitative real‐time polymerase chain reaction (qPCR)‐based assays selective for American bullfrog (Rana [Lithobates] catesbeiana), Burbot (Lota lota), Lake trout (Salvelinus namaycush), and Quillback rockfish (Sebastes maliger). The chosen target species vary in range, habitat, and degree of relatedness to their sympatric species that, consequently, impact eDNA assay design difficulty. We demonstrate the effectiveness of unikseq through assay validation and characterization using DNA from voucher specimens, synthetic DNA, and, where possible, field samples, to verify the specificity and sensitivity of the newly designed assays. By facilitating whole mitogenome sequence comparison, the creation of high‐performing eDNA assays is substantially enhanced. Having several adjustable parameters for specifying user requirements within unikseq, this approach can facilitate the identification of suitable regions for a broad range of applications requiring nucleotide sequence comparisons.
Recalibrating Bioethics for the Reality of Interdependence: The Challenge of Collective‐Impact Problems
Authors: Solomon Mildred Z. 
Published: June 2023

AbstractBioethics in the twenty‐first century is confronting what one might call “collective‐impact problems.” The ethics guidance and policies that are developed to address these kinds of problems will affect not only individuals but everyone living and future generations too. With many collective‐impact problems, all parties will eventually be worse off if there is a failure to develop solutions to head off damage to the shared environment. However, the effects are not felt equally throughout and across societies; some groups are hit far worse. To address collective‐impact problems, bioethics needs to recalibrate. Our field, and especially American bioethics, should find a better balance between individual rights and the best interests of the group, develop more robust tools for examining structural inequities that damage people's health and well‐being, and study how to engage the public in learning about and shaping ethics guidance for these complex problems.
Effectiveness of online HIV treatment services in the context of the COVID‐19 pandemic
Authors: Han Jing , Zhang Hanxi , Su Ye , Zhang Fujie 
Published: June 2023

AbstractBackgroundThe COVID‐19 pandemic has created challenges with respect to HIV care services. Remote online services might provide an effective method for health service delivery to people living with HIV (PLHIV). Few studies have focused on the efficacy of telemedical services for PLHIV and the effect of antiretroviral treatment via online services in China.MethodsWe developed a platform called the “No. 8 Health” for online antiretroviral drug collection and delivery services in Beijing from January 21 to June 30, 2022. We evaluated the online treatment service according to viral load suppression rates and compared differences in social characteristics between PLHIV who received antiretroviral drugs through online or offline treatment services.ResultsBy June 2022, 9528 PLHIV had received outpatient treatment services, among which 44.6% (4031/9528) used the online treatment and drug delivery services for a total of 5590 person‐times. The satisfaction rate was 100%. Rates of viral load suppression among PLHIV who initiated antiretroviral therapy (ART) in 2020 and 2021 were 96.4% and 93.1%, respectively. Results showed that the viral load suppression rate was 97.9%. Regarding HIV rapid self‐testing, 4513 men who have sex with men used the online HIV rapid testing service. The number of users was approximately the same as in 2021, but both were slightly lower than those in 2020.ConclusionThis study was the first to evaluate the effect of online drug collection and delivery services and virologic outcomes among PLHIV in China. The online service helped with maintenance of ART services, but the COVID‐19 pandemic still had some impacts on viral load suppression.
Post‐transplant lymphoproliferative disease in children, adolescents, and young adults
Authors: Gross Thomas G. , Rubinstein Jeremy D. 
Published: June 2023

AbstractPost‐transplant lymphoproliferative disease (PTLD) remains a major complication of transplantation. PTLD is a rare entity and very heterogenous making consensus on diagnosis and treatment very challenging. The majority are Epstein‐Barr virus (EBV) driven, CD20+ B‐cell proliferations. PTLD does occur following hematopoietic stem cell transplant (HSCT), but due to the relative short risk period and efficacy of pre‐emptive therapy, PTLD following HSCT will not be discussed in this review. This review will focus on the epidemiology, role of EBV, clinical presentation, diagnosis and evaluation and the current and emerging treatment strategies for pediatric PTLD following solid organ transplantation.
Peripheral T‐cell lymphomas
Authors: Broccoli Alessandro , Zinzani Pier Luigi 
Published: June 2023

AbstractThe treatment of peripheral T‐cell lymphomas is challenging, as they often display a severe prognosis and lack effective treatment strategies. We will try to answer three burning questions: can we differentiate the initial treatment based on the histotype and the clinical presentation of peripheral T‐cell lymphoma patients? Do we require an autologous stem cell transplantation in all patients? Is there room for improvement in the setting of relapsed and refractory disease?