bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pendampingan Peningkatan Pengetahuan Penulisan Kutipan Pada Kreativitas Masyarakat Menulis Taman Bacaan Masyarakat Kedai Proses Rangkasbitung
Authors: Karyaningsih Dentik , Fernando Donny , Rizky Irham Faridz , Agustini Lusi 
Published: February 2023

Pada Taman Bacaan Masyarakat Kedai Proses Rangkasbitung terdapat kelompok kreativitas menulis. Dalam menulis suatu karya tulis baik itu karya ilmiah, cerpen, majalah lainnya agar menghindari praktek plagiasi. Perlunya Teknik menulis kutipan atau sitasi pada karya tulis merupakan suatu upaya untuk menghindari terjadinya praktek plagiasi. Selain itu pemanfaatan Management Reference sebagai tools dapat membantu untuk menghindari terjadinya plagiasi. Pengabdian pada masyarakat ini dilakukan dengan metode wawancara, workshop serta pendampingan. Hasil dari workshop pengabdian pada masyarakat ini adalah adanya peningkatan pengetahuan penulisan kutipan atau sitasi dengan Management Reference terdapat peningkatan sebanyak 51.5% peningkatan peserta yang memahami kutipan atau sitasi, dan 80.1 % yang dapat menggunakan tools Management Reference.
Upgrading Skill Pekerja Guna Mendukung Tata Kelola Administrasi Melalui Pelatihan Optimalisasi Aplikasi Perkantoran Pada Federasi Serikat Pekerja Kimia, Energi Dan Pertambangan Seluruh Indonesia (Fsp Kep Spsi) Se-Provinsi Banten
Authors: Harsiti Harsiti , Setyawan Agus , Triono Sigit Haris , Johan Afif 
Published: February 2023

Upraging Skill atau keahlian sumber daya manusia dipandang sangat penting dilakukan oleh perusahaan, hal ini bertujuan agar sumber daya manusia lebih produktif dan mampu bersaing secara global dan mampu menjawab tantangan di era digitalisasi ini. Program pengabdian kepada masyarakat ini dilaksanakan dengan target dan sasarannya adalah para pekerja yang menjadi anggota atau pengurus cabang pada Federasi Serikat Pekerja Kimia, Energi dan Pertambangan Serikat Pekerja Seluruh Indonesia (FSP KEP SPSI) Provinsi Banten. Permasalahan yang pada saat ini dihadapi adalah tata kelola administrasi perkantoran pada masing-masing kantor cabang yang ada di wilayah Provinsi Banten belum dilaksanakan dengan baik, karena keterbatasan pemahaman Pekerja tentang teknologi informasi dan komunikasi yang belum merata, khususnya penggunaan aplikasi perkantoran yang belum optimal digunakan, khususnya untuk keperluan komunikasi secara tertulis melalui surat-menyurat, pembuatan laporan-laporan dan sejenisnya.serta komunikasi yang memanfaatkan teknologi informasi seperti video conference atau sejenisnya untuk keperluan rapat online. Penyebab terjadinya masalah ini adalah karena tidak meratanya sebaran pendidikan sehingga para pekerja kurang memahami tentang tata Kelola administrasi dengan memanfaatan teknologi informasi, serta tidak semua perusahaan yang tergabung dalam FSP KEP SPSI ini menitikberatkan pada bidang teknologi informasi. Solusi yang ditawarkan untuk mengatasi permasalahan ini yaitu dengan memberikan pelatihan terkait dengan pengantar teknologi informasi, pengenalan hardware-software dan dasar-dasar IT Troubleshooting, pelatihan optimalisasi aplikasi perkantoram (Microsoft Office), Optimalisasi dan tata cara menggunakan penyimpanan online (Cloud Storage) dan Optimalisasi Aplikasi Zoom Meeting. Kegiatan ini dilaksanakan kurang lebih 3 (tiga) bulan dan selebihnya dilakukan pendampingan sebagai upaya memonitoring penyerapan materi yang telah disampaikan oleh Narasumber. Hasil dan luaran kegiatan PkM ini berupa publikasi dalam seminar nasional atau jurnal nasional, media elektronik dan pembuatan video kegiatan yang dipublish melalui channel youtube.
Telaah Atas Konsep Khilafah Al-Mawardi (Studi Deskriptif Analisis)
Authors: Sahidin Amir 
Published: February 2023

<p><strong>Abstract</strong><strong></strong></p><p>Al-Mawardi was a Muslim scholar who was very well known for his Islamic political theory long before Western scholars recognized it. But, its very seldom to know that Al-Mawardi is also a scholar who is very concerned about <em>maqâshid al-syarî‘ah</em>. So it is rare to find researcher who uncover the links between Al-Mawardi's political thought and <em>maqâshid al-syarî‘ah</em>. In fact, both are related well and aimed to create maslahat for humans. Therefore, this article tries to examine the concept of al-Mawardi’s caliphate with the <em>maqâshid al-syarî‘ah</em> approach. Based on deep library research, it is found that the foundations built by Al-Mawardi in his concept of khilafah were strongly influenced by his understanding of <em>maqâshid al-syarî‘ah</em>, it is <em>maqâshid al-imâmah</em> value, wasilah law, maslahat and mudharat rules, and textual contextual. So that he succeeded in formulating laws that were beneficial both in the world and in the hereafter in line with the substance of <em>maqâshid al-syarî‘ah</em>. Thus, Al-Mawardi is one of the Islamic political thinkers who integrated <em>maqâshid al-syarî‘ah</em> into his concept of political thought, especially in the book <em>al-Ahkâm al-Shulthâniyyah</em>..</p><p> </p><p><strong>Keywords</strong><strong>:</strong><em> </em>Al-Mawardi, khilafah, <em>maqâshid al-syarî‘ah</em>, value</p><p> </p><p><strong>Abstrak</strong></p><p>Al-Mawardi merupkan sarjana muslim yang sangat terkenal dengan teori politik Islamnya jauh-jauh hari sebelum sarjana-sarjana Barat mengenal politik. Akan tetapi jarang yang mengetahui bahwa ternyata Al-Mawardi juga merupakan sosok sarjana yang sangat perhatian terhadap <em>maqâshid al-syarî‘ah</em>. Sehingga jarang sekali ditemukan para peneliti yang berusaha mengungkap keterkaitan politik Al-Mawardi dengan <em>maqâshid al-syarî‘ah</em>. Padahal, antara politik dan <em>maqâshid al-syarî‘ah</em> sangat berkaitan, yaitu sama-sama bertujuan untuk mewujudkan maslahat bagi manusia. Karenanya, artikel ini mencoba mengkaji konsep khilafah al-Mawardi dengan pendekatan <em>maqâshid al-syarî‘ah</em>. Melalui kajian kepustakaan yang mendalam dan otoritatif, ditemukan bahwa pondasi yang dibangun oleh Al-Mawardi dalam konsep khilafahnya sangat dipengaruhi oleh pemahamannya terhadap <em>maqâshid al-syarî‘ah</em>, yaitu berupa nilai-nilai <em>maqâshid al-imâmah, </em>hukum wasilah, kaidah maslahat dan mudarat, serta tekstual dan kontekstual. Sehingga ia berhasil merumuskan hukum-hukum yang bermaslahat baik di dunia maupun di akhirat selaras dengan subtansi <em>maqâshid al-syarî‘ah</em>. Dengan demikian, Al-Mawardi merupakan salah satu pemikir politik Islam yang mengintegrasikan <em>maqâshid al-syarî‘ah</em> ke dalam konsep pemikiran politiknya, khususnya dalam kitab <em>al-Ahkâm al-Shulthâniyyah</em>.</p><p> </p><p><strong>Kata Kunci</strong>: Al-Mawardi, khilafah, <em>maqâshid al-syarî‘ah</em>, nilai-nilai</p>
Data processing choices can affect findings in differential methylation analyses: an investigation using data from the LIMIT RCT
Authors: Louise Jennie , Deussen Andrea R. , Dodd Jodie M. 
Published: February 2023

Objective
A wide array of methods exist for processing and analysing DNA methylation data. We aimed to perform a systematic comparison of the behaviour of these methods, using cord blood DNAm from the LIMIT RCT, in relation to detecting hypothesised effects of interest (intervention and pre-pregnancy maternal BMI) as well as effects known to be spurious, and known to be present.

Methods
DNAm data, from 645 cord blood samples analysed using Illumina 450K BeadChip arrays, were normalised using three different methods (with probe filtering undertaken pre- or post- normalisation). Batch effects were handled with a supervised algorithm, an unsupervised algorithm, or adjustment in the analysis model. Analysis was undertaken with and without adjustment for estimated cell type proportions. The effects estimated included intervention and BMI (effects of interest in the original study), infant sex and randomly assigned groups. Data processing and analysis methods were compared in relation to number and identity of differentially methylated probes, rankings of probes by p value and log-fold-change, and distributions of p values and log-fold-change estimates.

Results
There were differences corresponding to each of the processing and analysis choices. Importantly, some combinations of data processing choices resulted in a substantial number of spurious ‘significant’ findings. We recommend greater emphasis on replication and greater use of sensitivity analyses.
First Report Occurrence of CIT and DHA AmpC β-lactamase Gene in Escherichia coli and Klebsiella pnuemoniae from Clinical Sample in South Eastern, Nigeria
Authors: Oluchi Akpu Peace , Onyinye Uzoeto Henrietta , Udeme Peter Ikemesit , Lovette Nomeh Onyinye , Chidiebube Nwuzo Agabus , Chinenye Ogba Rebecca , Romanus Iroha Ifeanyichukwu 
Published: February 2023

Background and Objectives: Over time, the enzymes AmpC β-lactamases have become more significant, due to their roles in antibiotic resistance among enterobacteriaceace especially in Escherichia coli and Klebsiella pnuemoniae. Due to increase multidrug resistant express by AmpC β-lactamases producing bacteria strain, the patients care in several hospital has been severely hampered. Hence, this study was designed to assess the occurrence of CIT and DHA AmpC β-lactamase gene in Escherichia coli and Klebsiella pnuemoniae from clinical sample in south eastern, Nigeria
Methodology: This study was conducted over an 8-month period on sixteen (16) non-repetitive clinical isolates of Escherichia coli and Klebsiella pnuemoniae collected from medical microbiology laboratory unit of Alex Ekweume Federal University Teaching Hospital in Abakaliki, Nigeria. The isolates were further identified using Standard microbiological Techniques and screened for cefoxitin resistance using a disc diffusion assay, followed by phenotypic tests using phenyl boronic acid assays for confirmation of AmpC β-lactamases production. Escherichia coli and Klebsiella pneumoniae strains were further screen for AmpC β-lactamase CIT and DHA genotype by polymerase chain reactions
Result: Of the sixteen (16) confirmed phenotypic AmpC β-lactamase producing bacteria, 100% of the AmpC β-lactamase genes (DHA and CIT) were detected in E. coli from wound and urine samples from both male and female patients. The overall proportion of AmpC β-lactamases gene in Klebsiella pneumoniae were DHA (100 %) and CIT (100 %), in both male and female.
Conclusion: This study indicate the occurrence of CIT and DHA AmpC genotype. The detection of AmpC β-lactamases in this study is of clinically importance as such bacteria are often MDR. Thus, being aware of the presence of AmpC β-lactamase-producing bacteria could be very beneficial for achieving more accurate epidemiological results as well as controlling their spread, while surveillance is required to track any further dissemination and emergence of other AmpC β-lactamase genotypes.
Possible Colchicine Poisoning: Case Study
Authors: Takeuchi Koh , Matsumoto Shinya , Yasumoto Yusuke , Kato Ryotaro 
Published: February 2023

We have experienced a case of colchicine toxicity presenting with rapidly progressive gastrointestinal symptoms, hemodynamic instability, and multiple organ failure.
An 86-year-old Japanese man presented to our hospital with subarachnoidal hemorrhage transferring from another hospital where he had been treated with colchicine 0.5 mg three times daily for an elevated uric acid level. During his admission, he had a nosocomial COVID-19 infection. Then, he developed loss of appetite, and significant diarrhea, which continued for two days. He then developed shock and hypoxia and was transferred to intensive care unit (ICU). The laboratory data revealed pancytopenia, acute kidney injury, lactic acidosis, marked coagulopathy, elevated troponin I, and C-reactive protein with poor cardiac function and hypotension refractory to vasopressors. Despite intensive care, he expired on 2nd day of ICU admission. Because his cardiac function was depressed from the beginning and was not respond to inotropic support, direct myocardial damage, rather than septic cardiomyopathy was suspected. We, therefore, emphasize that colchicine poisoning should be suspected in patients with access to the drug and the typical toxidrome.
The Other Ear in Unilateral Chronic Suppurative Otitis Media Clinical and Radiological Study
Authors: Taha Mesilhy Ghada Mesilhy , Shehata Emad Mohammed , Ali Erfan Fathy , Adel Khalifa Mohammed 
Published: February 2023

Background: Chronic suppurative otitis media (CSOM) refers to chronic irreversible inflammatory pathological tissue damage of the middle ear cleft mucosal lining. The aim of this study is to evaluate clinical and radiological study of the other ear in unilateral CSOM.
Methods: This prospective cohort study was carried out on 65 Cases with unilateral Chronic suppurative otitis media (CSOM) and their ages more than 5 years old. Cases were subdivided in to two groups: GroupⅠ: included 30 cases with unilateral mucosal CsOM and Group Ⅱ: included 30 cases with unilateral squamous CSOM.
All cases were subjected to clinical examination of the contralateral ear (CLE) (Otoscope, Microscope and Endoscopic examination by 0-degree telescope) as well as audiological examination.
Results: Unilateral CSOM, mainly found in young age females. The average duration of the disease was 5.1 years ± 3.7 years in group I and 7.2 ±5.6 years in group II, Abnormal tympanic membrane (TM) of CLEs was (43.1%) in both groups, In group I, CLE otoscope and microscopic examinations showed that (60%) with normal TM, (37.1%) with retracted TM and (2.9%) with glue TM, while endoscopic examination showed (56.7%) normal TM, (37.1%) retracted TM and (2.9%) glue TM, In group II, CLE otoscope examination showed that 16 normal TM (53.3%) and 14 retracted TM (46.7%), while microscopic examination showed that 13 normal TM (43.3%) and 17 retracted TM (56.7%) and endoscopic examination showed that 12 normal TM (40%),18 retracted TM (60%).
Conclusion: occurrences of structure abnormalities of the CLE in cases of unilateral CSOM of both squamous and mucosal types. The otoscope findings were primarily in the form of TM retraction in the squamous type, while the radiological and audiological abnormalities were more common in the squamous than mucosal type.
Association of Cognitive Impairment Screening Scores With Improvements in Speech Recognition and Quality of Life After Cochlear Implantation
Authors: Raymond Mallory J. , Ma Cheng , Schvartz-Leyzac Kara C. , Camposeo Elizabeth L. , Nguyen Shaun A. , Meyer Ted A. , McRackan Theodore R. 
Published: February 2023

ImportanceMany cochlear implant centers screen patients for cognitive impairment as part of the evaluation process, but the utility of these scores in predicting cochlear implant outcomes is unknown.ObjectiveTo determine whether there is an association between cognitive impairment screening scores and cochlear implant outcomes.Design, Setting, and ParticipantsRetrospective case series of adult cochlear implant recipients who underwent preoperative cognitive impairment screening with the Montreal Cognitive Assessment (MoCA) from 2018 to 2020 with 1-year follow-up at a single tertiary cochlear implant center. Data analysis was performed on data from January 2018 through December 2021.ExposuresCochlear implantation.Main Outcomes and MeasuresPreoperative MoCA scores and mean (SD) improvement (aided preoperative to 12-month postoperative) in Consonant-Nucleus-Consonant phonemes (CNCp) and words (CNCw), AzBio sentences in quiet (AzBio Quiet), and Cochlear Implant Quality of Life-35 (CIQOL-35) Profile domain and global scores.ResultsA total of 52 patients were included, 27 (52%) of whom were male and 46 (88%) were White; mean (SD) age at implantation was 68.2 (13.3) years. Twenty-three (44%) had MoCA scores suggesting mild and 1 (2%) had scores suggesting moderate cognitive impairment. None had been previously diagnosed with cognitive impairment. There were small to medium effects of the association between 12-month postoperative improvement in speech recognition measures and screening positive or not for cognitive impairment (CNCw mean [SD]: 48.4 [21.9] vs 38.5 [26.6] [d = −0.43 (95% CI, −1.02 to 0.16)]; AzBio Quiet mean [SD]: 47.5 [34.3] vs 44.7 [33.1] [d = −0.08 (95% CI, −0.64 to 0.47)]). Similarly, small to large effects of the associations between 12-month postoperative change in CIQOL-35 scores and screening positive or not for cognitive impairment were found (global: d = 0.32 [95% CI, −0.59 to 1.23]; communication: d = 0.62 [95% CI, −0.31 to 1.54]; emotional: d = 0.26 [95% CI, −0.66 to 1.16]; entertainment: d = −0.005 [95% CI, −0.91 to 0.9]; environmental: d = −0.92 [95% CI, −1.86 to 0.46]; listening effort: d = −0.79 [95% CI, −1.65 to 0.22]; social: d = −0.51 [95% CI, −1.43 to 0.42]).Conclusions and RelevanceIn this case series, screening scores were not associated with the degree of improvement of speech recognition or patient-reported outcome measures after cochlear implantation. Given the prevalence of screening positive for cognitive impairment before cochlear implantation, preoperative screening can be useful for early identification of potential cognitive decline. These findings support that screening scores may have a limited role in preoperative counseling of outcomes and should not be used to limit candidacy.
The pH‐Sensitive Optical Fiber Integrated CMCS‐PA@Fe Hydrogels for Photothermal Therapy and Real‐Time Monitoring of Infected Wounds
Authors: Min Yajun , Han Ruijia , Li Guanlin , Wang Xinyu , Chen Shilu , Xie Maobin , Zhao Zheng 
Published: February 2023

AbstractBacterial infections are one of the biggest threats to wound healing. Despite significant efforts in wound condition monitoring and treatment, significant challenges remain in real‐time wound monitoring and timely treatment. Herein, a kind of hydrogel with dual functions, which can not only quickly diagnose wound bacterial infection but also provide timely and effective treatment is developed. First, Carborxymethy chitosan (CMCS)‐Protocatechualdehyde (PA)@Fe hydrogels with double dynamic bonds are prepared by chelating PA@Fe with CMCS. Second, the pH‐sensitive Polydimethylsiloxane (PDMS) optical fibers are integrated into the CMCS‐PA@Fe hydrogels to obtain the pH‐sensitive optical fiber/CMCS‐PA@Fe hydrogels that exhibit good real‐time monitoring of the wound healing process. The tissue adhesion and self‐healing properties of the pH‐sensitive optical fiber/CMCS‐PA@Fe hydrogels can adapt to the movement and stretching of the skin. Meanwhile, with the assistance of the photothermal effect, the hydrogels have a high antibacterial effect (>99.9%). In addition, the pH‐sensitive optical fiber/CMCS‐PA@Fe hydrogels also show an excellent therapeutic effect in the wound infection model. Moreover, reliable and timely wound pH information can be sent to intelligent devices through microcomputers to monitor the healing status. Overall, the pH‐sensitive optical fiber/CMCS‐PA@Fe hydrogels provide an entirely new platform for developing smart, real‐time diagnostics and timely wound treatment.
Exploration and Application of Self‐Healing Strategies in Lithium Batteries
Authors: Ma Weiting , Wan Shuang , Cui Xiurui , Hou Guolin , Xiao Ying , Rong Junfeng , Chen Shimou 
Published: February 2023

AbstractLithium batteries (LBs) are developed tremendously owing to their excellent energy density as well as cyclic persistence, exhibiting promising applications from portable devices to e‐transportation and grid fields. However, with the ever‐increasing demand for intelligent wearable electronics, more requests are focused on high safety, good durability, and satisfied reliability of LBs. The self‐healing route, which can simulate the ability of organic organisms to repair damage and recover initial function through its intrinsic vitality, is believed to be an efficient strategy to alleviate the unavoidable physical or chemical fatigue and damage issues of LBs, beneficial for the realization of the above mentioned high requests. In this review, the applicability and development of self‐healing materials are summarized in electrodes, electrolytes, and interfacial layers in recent years, focusing on exploring the feasibility of different self‐healing strategies in LBs, discussing the advantages and disadvantages of existing strategies in different parts of batteries, and indicating the possible research directions for beginners who are interested in this field. Finally, the critical challenges and the future research directions as well as opportunities are prospected.
Collective Motion of Quincke Rollers with Fully Resolved Hydrodynamics
Authors: Imamura Shun , Sawaki Kohei , Molina John J. , Turner Matthew S. , Yamamoto Ryoichi 
Published: February 2023

AbstractHydrodynamic effects are known to significantly affect the collective behavior of wet active matter systems. However, the non‐linear many‐body nature of these interactions makes them very challenging to analyze, particularly in dense suspensions. Quincke rollers are one of the canonical examples of artificial microswimmers. These are active particles that move freely above a plate due to the torque generated by a uniform DC electric field. A system involving many such particles exhibits a variety of collective dynamics, such as the disordered gas, polar liquid, and active crystal states. This work accomplishes numerical simulations of a 3D system containing many rollers in order to explicitly resolve the hydrodynamic interactions and understand the role these play in the resulting active dynamics. It reveals that the far‐field hydrodynamic effects tend to drive ordered collective motion, while the near‐field effects tend to drive disordered collective behavior, and reproduce diverse collective behavior while capturing the role of hydrodynamic effects between rollers without resorting to the approximations previously employed.
Single‐Cell Landscape Highlights Heterogenous Microenvironment, Novel Immune Reaction Patterns, Potential Biomarkers and Unique Therapeutic Strategies of Cervical Squamous Carcinoma, Human Papillomavirus‐Associated (HPVA) and Non‐HPVA Adenocarcinoma
Authors: Qiu Junjun , Qu Xinyu , Wang Yumeng , Guo Chenyan , Lv Bin , Jiang Qian , Su Wentao , Wang Li , Hua Keqin 
Published: February 2023

AbstractCervical adenocarcinomas (ADCs), including human papillomavirus (HPV)‐associated (HPVA) and non‐HPVA (NHPVA), though exhibiting a more malignant phenotype and poorer prognosis, are treated identically to squamous cell carcinoma (SCC). This clinical dilemma requires a deeper investigation into their differences. Herein a transcriptomic atlas of SCC, HPVA, and NHPVA‐ADC using single‐cell RNA (scRNA) and T‐cell receptor sequencing (TCR‐seq) is presented. Regarding structural cells, the malignancy origin of epithelial cells, angiogenic tip cells and two subtypes of fibroblasts is revealed. The promalignant properties of the structural cells using organoids are further confirmed. Regarding immune cells, myeloid cells with multiple functions other than antigen presentation and exhausted T lymphocytes contribute to immunosuppression. From the perspective of HPV infection, not only is HPV‐dependent and independent cervical cancer oncogenesis proposed but also three immune reaction patterns mediated by T cells (coordinated/inactive/imbalanced) are identified. Strikingly, diagnostic biomarkers to distinguish ADC from SCC are discovered and prognostic biomarkers with marker genes for malignant epithelial cells, tip cells, and SPP1/C1QC macrophages are generated. Importantly, the efficacy of anti‐CD96 and anti‐TIGIT, not inferior to anti‐PD1, in animal experiments is confirmed and targeted therapies specifically for HPV‐positive SCC, HPVA and NHPVA‐ADC, providing essential clues for further clinical trials, are proposed.