bluuebunny/crossref_metadata_2025_split huggingface dataset:
Far‐field potential of the compound muscle action potential as a reliable marker in amyotrophic lateral sclerosis
Authors: Higashihara Mana , Yamazaki Hiroki , Izumi Yuishin , Kobayashi Masahito , Nodera Hiroyuki , Oishi Chizuko , Iwata Atsushi , Murayama Shigeo , Kaji Ryuji , Sonoo Masahiro 
Published: April 2023

AbstractIntroduction/AimsReliable neurophysiological markers in amyotrophic lateral sclerosis (ALS) are of great interest. The compound muscle action potential (CMAP) amplitude has been a conventional marker, although it is greatly influenced by the electrode position. We propose the far‐field potential of the CMAP (FFP‐CMAP) as a new neurophysiological marker in ALS.MethodsPatients with ALS and age‐matched healthy controls were enrolled. We used a proximal reference (pref) in addition to the conventional distal reference (dref). Routine CMAP was recorded from the belly‐dref lead and FFP‐CMAP from the dref‐pref lead for the ulnar and tibial nerves. Multiple point stimulation motor unit number estimation (MUNE) was also examined in the ulnar nerve. Inter‐rater reproducibility was evaluated by two examiners, and some patients were followed up every 3 mo for 1 y.ResultsWe tested 17 patients with ALS and 10 controls. The amplitudes of routine CMAP and FFP‐CMAP in the ulnar and tibial nerves, and hypothenar MUNE value in the ulnar nerve were significantly decreased in ALS compared to controls. Ulnar FFP‐CMAP achieved the highest inter‐rater intraclass correlation coefficient (ICC) value (0.942) when compared with routine CMAP (0.880) and MUNE (0.839). The tibial FFP‐CMAP had a higher ICC value (0.986) than the routine CMAP (0.697). In this way, the FFP‐CMAP showed high inter‐rater reproducibility because its shape was not much influenced by the electrode position. During 1‐y follow‐up, decline of CMAP, FFP, and MUNE showed significant correlations with the Amyotrophic Lateral Sclerosis Functional Rating Scale ‐ Revised (ALSFRS‐R).DiscussionThe FFP‐CMAP shows promise as a reliable marker for ALS.
Cross‐cultural adaptation, translation, and validation of the Arabic version of the short form of Neurogenic Bladder Symptoms Score
Authors: Khadour Younes A. , Ebrahem Bashar M. , Khadour Fater A. 
Published: April 2023

AbstractBackgroundThe Neurogenic Bladder Symptom Score—Short Form (NBSS‐SF) evaluates the impact of disease‐specific symptoms on the quality of life (QoL) in individuals with neurogenic bladder (NB). There is no data on the validity and reliability of the NBSS‐SF questionnaire in the Arabic language, so this study aimed at providing the translation, cultural adaptation, and validation of the Arabic NBSS‐SF in patients with multiple sclerosis (MS) and spinal cord injury (SCI).MethodsThe original English language version of the NBSS‐SF was translated into Arabic according to the cultural and linguistic adaptation algorithm. People with SCI and MS completed the NBSS‐SF, demographic and clinical information, and Qualiveen QoL questionnaire. Responses were recorded twice within a 14‐day period. Psychometric properties such as content validity, construct validity, internal consistency, and test–retest reliability were tested. Internal consistency and test–retest reliability was evaluated using Cronbach's alpha, and the intraclass correlation coefficient (ICC), respectively. Construct validity was assessed by comparing the NBSS‐SF with the Qualiveen questionnaire.ResultsThirty‐nine patients with MS and 97 with SCI participated in the study. The internal consistency for the overall NBSS‐SF score (Cronbach's α of 0.82) and for each subdomain was variable (urinary incontinence 0.82; storage/voiding 0.73; consequences 0.53). ICC was 0.93 for the overall score and 0.96 for the urinary incontinence subdomain, 0.74 for storage/voiding, and 0.91 for consequences. The correlation analysis showed a significantly strong correlation between the QoL item of NBSS‐SF and the Qualiveen total score (r = 0.72, p < 0.000). There was a significant moderate positive correlation between the total scores on the Arabic version of the NBSS‐SF and the subdomains of the Qualiveen, including limitations (r = 0.51, p = 0.04), fears (r = 0.57, p = 0.04), feelings (r = 0.46, p = 0.01), and constraints (r = 0.59, p = 0.03).ConclusionsOur results showed that the Arabic version of NBSS‐SF is a valid and reliable instrument for evaluating neurogenic lower urinary tract dysfunction symptoms in the Arabic population suffering from SCI and MS.
The impact of postinjection urinary tract infection on efficacy of intravesical onabotulinumtoxinA—A secondary analysis
Authors: Guirguis Hanna Marina , Bradley Megan , Zyczynski Halina , Wang Li , Giugale Lauren 
Published: April 2023

AbstractObjectivesTo compare treatment response in women who did and did not develop a urinary tract infection (UTI) within 14 days after intravesical onabotulinumtoxinA injections for treatment of refractory urgency urinary incontinence (UUI).MethodsThis is a secondary analysis of women who received Onabotulinumtoxin A in the Refractory Overactive Bladder: Sacral Neuromodulation vs Botulinum Toxin Assessment (ROSETTA) Trial. Participants were grouped by presence or absence of UTI within 14 days of injection. UTI was defined as symptomatic with positive urine culture per the primary ROSETTA protocol. Our primary outcome was change from baseline in mean number of UUI episodes based on monthly 3‐day bladder diaries averaged over 6 months. We performed t tests and chi‐square/Fisher's exact for continuous and categorical variables. A p value of <0.05 was considered statistically significant.ResultsOf 187 participants in the onabotulinumtoxinA arm, 10 (5.3%) experienced UTI within 14 days of injection, and 177 (94.7%) did not. At baseline, groups did not differ in demographics, mean UUI episodes per day (no UTI [5.37 ± 2.65] vs. UTI [6.40 ± 3.02], p = 0.24), or other diary parameters. For our primary outcome, groups did not differ in the change in mean daily UUI episodes at 1 month (no UTI [−4.29 ± 2.75] vs. UTI [−3.74 ± 2.01]; mean difference [95% confidence interval, CI] −0.55 [−2.39 to 1.28], p: 0.55) or 6 months (no UTI [−3.63 ± 2.89] vs. UTI [−2.15 ± 3.18]; mean difference [95% CI] −1.48 [−3.44 to 0.48], p: 0.14).ConclusionsUTI within 14 days after intravesical injection of onabotulinumtoxinA for refractory UUI was not significantly associated with inferior treatment response at 1 or 6 months.
Service center location problems with decision dependent utilities and a pandemic case study
Authors: Luo Fengqiao , Mehrotra Sanjay 
Published: April 2023

AbstractWe study a service center location problem with ambiguous utility gains upon receiving service. The model is motivated by the problem of deciding medical clinic/service centers, possibly in rural communities, where residents need to visit the clinics to receive health services. A resident gains his utility based on travel distance, waiting time, and service features of the facility that depend on the clinic location. The elicited location‐dependent utilities are assumed to be ambiguously described by an expected value and variance constraint. We show that despite a non‐convex nonlinearity, given by a constraint specified by a maximum of two second‐order conic functions, the model admits a mixed 0‐1 second‐order cone (MISOCP) formulation. We study the non‐convex substructure of the problem, and present methods for developing its strengthened formulations by using valid tangent inequalities. Computational study shows the effectiveness of solving the strengthened formulations. Examples are used to illustrate the importance of including decision dependent ambiguity. An illustrative example to identify locations for Covid‐19 testing and vaccination is used to further illustrate the model and its properties.
The psychometric properties of nursing image measurement instruments: A systematic review
Authors: Zhou Lu , Sukpasjaroen Khunanan , Cai EnLi , Moonsri Kristiya , Imsiri Prakobkiat , Chankoson Thitinan 
Published: April 2023

AbstractAimTo identify the measures assessing the nursing image, and to analyse, evaluate and synthesize the psychometric properties of these available instruments.DesignA systematic review of the psychometric properties of instruments assessing the nursing image. The system review has been registered in the PROSPERO database with the registration number CRD42020221511.MethodsThe systematic review was conducted according to COSMIN guidelines. Search strategies were run in CINAHL, MEDLINE, APA PsycINFO, Web of Science, Scopus, COSMIN systematic review database, Cochrane Library and China National Knowledge Infrastructure (CNKI). Two reviewers independently screened the studies, extracting the psychometric properties of the included study characteristics and instruments. The methodological quality of the studies, instrument measurement performance, risk of bias and grade of evidence were evaluated and disagreements were resolved via discussion.ResultsThe search strategy yielded a total of 24 studies and 11 instruments assessing nursing image. None of the measures fulfilled all criteria in the COSMIN Risk of Bias checklist. The Nurses Self‐Concept Instrument (NSCI) and the Nurses Self‐Concept Questionnaire (NSCQ) were recommended for measuring the professional image of nursing, and the Nursing Brand Image Scale (NBIS) have the potential to be recommended for measuring a more comprehensive image of nursing. Every instrument evaluated in this review had different characteristics in the nursing image (e.g. the traditional image, the professional image, and the brand image). Therefore, the selection of the most appropriate instrument depends on the psychometrics, the context and the aim of the assessment.
Nurses' second victim experience, job insecurity, and turnover intention: A latent profile analysis
Authors: Shao Yanru , Li Shanshan , Wei Lili , Shan Xinzhi , Zhou Dan , Zhang Yan , Wei Holly 
Published: April 2023

AbstractNurses are greatly affected by patient safety incidents, but little is known about the classifications of nurses' second victim experiences and their effects on job insecurity and turnover intention. This study aimed to identify the profiles of nurses' second victim experiences, including perceived support and distress, and explore the effects of the different experiences on nurses' job insecurity and turnover intention. A convenience sample of 2000 nurses, who were directly involved in patient safety incidents within a year at 25 hospitals in 13 provinces in China, was invited to participate. The online surveys included the Second Victim Experience and Support Tool‐Chinese version, job insecurity scale, and turnover intention scale. Data were analyzed using regression and latent profile analysis to identify second‐victim nurses' different experience predictors and examine the relationships among the factors. A total of 1298 valid questionnaires were obtained. Three profiles of second victim experiences were identified. Univariate analysis demonstrated that nurses' experience, education level, hospital type, specialty, working hours, credentials, clinical ladder, type of employment, income, training on adverse events, and the type of adverse event were statistically significant (p < 0.05) variables differentiating the three profiles. After controlling these significant variables, the multiple regression analysis showed that the higher the support and the lower the distress level of the second victim, the lower the job insecurity and turnover intention. This study highlights the significance of nurse' leader and organizational support. Nursing leaders should recognize nurses' second‐victim experiences, provide the support nurses need, and help them reduce job insecurity and turnover intention.
Insights into atomic‐electronegativity‐controlled excited state intramolecular proton transfer behavior for the novel oxazolonapthoimidazo[1,2‐a]‐pyridine (ONIP) compound: A time‐dependent density functional theory study
Authors: Liu Rivaille , Zhao Jinfeng , Li Xiaoxiao , Jin Bing , Tang Zhe 
Published: April 2023

AbstractIn this work, we mainly focus on probing into the effects of atomic electronegativity on photo‐induced hydrogen bond (i.e., O–H···N) effects and excited state intramolecular proton transfer (ESIPT) processes for a novel fluorescent chemical probe ONIP derivatives (i.e., ONIP‐O, ONIP‐S, and ONIP‐Se). First, insights into optimized structural geometries and related infrared vibrational spectra, we clarify that the hydrogen bond O–H···N interaction could be strengthened via photoexcitation. Further, via predicting hydrogen bonding energy EHB, we quantificationally present that the S1‐state hydrogen bonding strengthening behavior should be more distinct with lower atomic electronegativity. When it comes to vertical photo‐induced excitation, the intramolecular charge transfer process happens and the charge redistribution plays roles in promoting ESIPT behavior. It is worth mentioning the energy gap between highest occupied molecular orbital and lowest unoccupied molecular orbital show that low atomic electronegativity should be more favorable to ESIPT process. Finally, based on the restricted optimization method, we construct the potential energy curves along with hydrogen bond wire for ONIP‐O, ONIP‐S, and ONIP‐Se. By exploring the conformation of potential energy curves and potential energy barriers, we disclose the detailed atomic‐electronegativity‐controlled ESIPT dynamical behaviors for ONIP system.
Carbon nanotube films embedded with Cu@C nanocubes for electromagnetic interference shielding
Authors: Ye Jinhong , Wang Yanqin , Luo Liqiang , Qian Kunpeng , Zhou Jianyu , Miao Miao , Feng Xin 
Published: April 2023

AbstractFlexible carbon tube films for electromagnetic interference (EMI) shielding are assembled by mixing the well‐aligned Cu@C core‐shell nanocubes with multi‐walled carbon nanotubes (MWCNTs). The Cu@C core‐shell nanocubes are achieved by the thermal pyrolysis of polyvinylpyrrolidone (PVP) coating on Cu2O nanocubes. With the optimal PVP concentration of 1.5 mg/mL, the Cu@C/MWCNTs composite film with ultra‐thin thickness (52.2 μm) displays good conductivity of 12.5 S cm−1 and excellent specific EMI shielding value of 510.73 dB mm−1, which is higher than the pure MWCNTs film (439.50 dB mm−1) under the same weight condition. Moreover, the 1.5 mg/mL‐Cu@C/MWCNTs composite film exhibits highly mechanical repeatability after being bended for 10,000 cycles. The carbon layers protecting metal nanoparticles can partly replace precious carbon nanotubes to construction highly flexible composite film with anticipated electrical conductivity, which have a good application prospect for thin, lightweight and flexible EMI shielding fields.
How to reconcile renewable energy and agricultural production in a drying world
Authors: Schweiger Andreas H. , Pataczek Lisa 
Published: April 2023

Societal Impact StatementRenewable energies such as photovoltaics can mitigate climate change by replacing fossil fuels, but they will compete with other forms of land use when implemented in open space. Agrivoltaics provide a promising approach to reconciling food and energy needs by allowing for agricultural and electrical power production on the same area of land. Agrivoltaics have a high potential to attenuate negative effects of drought on crop growth and, thus, can help to increase resilience of agricultural production under increasingly variable environmental conditions. This drought attenuation potential will be especially relevant for regions where drought and population growth co‐occur.SummaryWater scarcity is threatening food security and other, plant‐related ecosystem services. Renewable energy production provides a sustainable strategy to replace fossil fuel and, by this, mitigate climate change. However, common forms of renewable energy production such as photovoltaics in open space directly compete with agriculture. Agrivoltaics are proposed as a promising technology to reconcile food and energy needs by allowing for agricultural and electrical power production on the same area of land. However, general understanding of the potential of agrivoltaics to facilitate crop yield under changing climatic conditions is lacking. In this study we provide an overview on the effects of agrivoltaics on microclimate and crop growth and yields. We furthermore quantify the global potential of agrivoltaics to attenuate drought effects on crops and develop a conceptual framework for evaluating interactions between solar power and agricultural production under changing climatic conditions. Generally, shading by agrivoltaics will reduce yield in comparison to maximum possible yield under unshaded, well‐watered conditions but can reduce interannual variation in yields caused by drought, thus, increase resilience of agricultural production. This drought attenuation potential of agrivoltaics seems to be especially promising in the drought prone regions of the world. Land use efficiency of agrivoltaic systems is directly linked the degree of crop shading which covaries with the drought attenuation potential but will ultimately be guided by political decisions on how to weight energy production vs. food security. The latter depends on economic, societal and ecological aspects related to the implementation of agrivoltaics.
Effect of maleylation and denaturation of human serum albumin on its interaction with scavenger receptors
Authors: Li Xiao‐Lei , Yan Zeng‐Shuai , Ma Yu‐Qiang , Ding Hong‐Ming 
Published: April 2023

AbstractThe specific recognition of serum proteins by scavenger receptors is critical and fundamental in many biological processes. However, the underlying mechanism of scavenger receptor‐serum protein interaction remains elusive. In this work, taking scavenger receptors class A1 (SR‐A1) as an example, we systematically investigate its interaction with human serum albumin (HSA) at different states through a combination of molecular docking and all‐atom molecular dynamics simulations. It is found that native HSA can moderately bind to collagen‐like (CL) region or scavenger receptor cysteine‐rich (SRCR) region, with both electrostatic (ELE) and van der Waals (VDW) interactions, playing important roles. After maleylation, the binding energy, particularly the ELE energy, between HSA and CL region is significantly enhanced, while the binding energy between HSA and SRCR region remains nearly unchanged. Additionally, we also observe that unfolding of the secondary structures in HSA leads to a larger contact surface area between denatured HSA and CL region, but has little impact on the HSA‐SRCR region interaction. Therefore, similar to maleylated HSA, denatured HSA is also more likely to bind to the CL region of SR‐A1.
Structural modification of (3E)‐4,8‐dimethyl‐1,3,7‐nontriene enhances its ability to kill Plutella xylostella insect pests
Authors: Zhao Mengjie , Tao Zhen , Wang Ling , Wang Tengyue , Wang Chuanhong , Li Shuai , Huang Shijie , Wei Yuming , Jiang Taoshan , Li Peijin 
Published: April 2023

AbstractBACKGROUNDPlant secondary metabolites and their modified derivatives play an important role in the discovery and development of novel insecticides. The natural plant product (3E)‐4,8‐dimethyl‐1,3,7‐nontriene (DMNT) has been proven to be able to effectively repel and kill the lepidopteran insect pest Plutella xylostella.RESULTSIn this study, four oxygenated derivatives of DMNT were synthesized by allylic hydroxylation and subsequent etherification or esterification. Bioassays on P. xylostella larvae showed that the compounds DMNT‐OCH3 (2), DMNT‐OCy (3) and DMNT‐OAc (4) were more toxic to the larvae than DMNT alone. The most pronounced effect was observed for compound 2, which showed a 22.23% increase in lethality at a concentration of 0.25 μm. Moreover, the peritrophic matrix (PM) barrier in the insect midgut was more severely damaged by compounds 2, 3 and 4 than by DMNT. The median lethal concentration (LC50, 48 h) of compounds 2, 3 and 4 on P. xylostella was determined to be 0.98, 1.13 and 1.11 mg mL−1, respectively, which is much lower than the commercial insecticides eucalyptol (2.89 mg mL−1) and thymol (2.45 mg mL−1).CONCLUSIONThese results suggested that oxygenated DMNT derivatives offer a significantly improved killing effect over DMNT on P. xylostella. This work has provided a basis for further design, structural modification and development of DMNT as botanical insecticides. © 2023 Society of Chemical Industry.
Population performance and detoxifying and protective enzyme activities of four thrips species feeding on flowers ofMagnolia grandiflora(Ranunculales: Magnolia)
Authors: Cao Yu , Qi Guiling , Jiang Feiyu , Meng Yonglu , Wang Chun , Gu Zhaoyang , Gao Yulin , Reitz Stuart R , Li Can 
Published: April 2023

AbstractBACKGROUNDDifferent thrips species can co‐occur on the same flowers with different dominance degrees. To accurately evaluate the population performance on different thrips species onMagnolia grandifloraflowers, we investigated the diversity of thrips species and their population dynamics both in the field and laboratory. In addition, the activities of detoxifying and protective enzymes in thrips were also measured.RESULTSField investigations revealed that four thrips species (Thrips hawaiiensis,Thrips flavidulus,Frankliniella occidentalis, andThrips coloratus) coexisted onM. grandifloraflowers. They were ranked, from highest population density to lowest, as follows:T. hawaiiensis > T. flavidulus > F. occidentalis > T. coloratus. In laboratory investigations, the species were ranked, from fastest developmental rates to slowest, as follows:F. occidentalis > T. hawaiiensis > T. flavidulus > T. coloratus; and from largest population size to smallest, as follows:T. hawaiiensis > F. occidentalis > T. flavidulus > T. coloratus. Biochemistry assays showed that the four species differed in their activities of detoxifying enzymes (carboxylesterase, glutathione‐S‐transferase, and cytochrome P450) and protective enzymes (superoxide dismutase, peroxidase) in both laboratory and field strains.CONCLUSIONDifferences in population performance among these four thrips onM. grandifloramay be related to their activity levels of physiological enzymes. The variations in thrips population performance between the field and the laboratory could be due to differences in environmental conditions.T. hawaiiensisshowed a strong host preference forM. grandiflora, and thus it has the potential to be a dangerous pest in horticultural plants. © 2023 Society of Chemical Industry.
Exploiting exotic pathogens as mycoherbicides against invasive alien weeds: Japanese knotweed as a case study
Authors: Kurose Daisuke , Seier Marion K , Evans Harry C 
Published: April 2023

AbstractPlant species have been introduced increasingly into non‐native ranges, where many have become exotic weeds with adverse impacts on native ecosystems, as well as on farming and other livelihoods. In biological control, the classical or inoculative approach is the one most commonly used for the management of invasive alien weeds and is based on the use of co‐evolved natural enemies from the native range to control the invasive weed. Typically, the inundative or mycoherbicide approach targets problematic weeds using local plant pathogens that, in the case of introduced species, have ‘jumped’ onto the exotic host. The leaf‐spot fungus, Mycosphaerella polygoni‐cuspidati, co‐evolved with its host, Reynoutria (Fallopia) japonica (Japanese knotweed), in Japan and has a unique history of being investigated both as a classical biological control agent and a mycoherbicide against this highly invasive weed in the United Kingdom and North America. Here, we highlight our research on M. polygoni‐cuspidati as part of a biological control programme for Japanese knotweed and review the potential of mycoherbicides using exotic pathogens for the management of invasive alien weeds. © 2023 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.