bluuebunny/crossref_metadata_2025_split huggingface dataset:
NOx Reduction with Resistance Against Multiple Poisoning Agents over Inherent SO42− Modified V2O5/CeO2 Catalysts
Authors: Jia Xinyu , Liu Xiangyu , Zhang Hengxiang , He Jiebing , Zhang Kai , Hu Xiaonan , Han Lupeng , Zhang Dengsong 
Published: June 2023

AbstractIt's a big challenge to use commercial catalysts in the non‐electric industries because complex flue gas containing alkali metals, heavy metals and SO2 could deactivate catalysts. In this study, we demonstrate that inherent SO42− modified V2O5/CeO2 catalysts exhibit remarkable resistance to multi‐poisons including K, Pb and SO2. The mechanisms of multiple poisoning resistance are revealed, and the evolutions of interactions between various poisons and different catalysts are elucidated. It is evidenced that K or Pb could bond on the inherent SO42− sites of catalysts; the interaction of K with Pb could impair the poisoning effects of K&Pb on catalysts; the newly formed surface SO42− species with the introduction of SO2 could bond with K dominantly, decrease the interaction between K and Pb, and relieve the effects of Pb on catalysts. K&Pb&SO2 co‐poisoned catalysts still maintain high adsorption of NH3/NH4+ and NOx species and a superior NOx reduction efficiency via the Langmuir‐Hinshelwood reaction pathway, leading to the ultra‐strong resistance of multi‐poisons. This work successfully achieves efficient and stable NOx removal in the presence of K&Pb&SO2, and sheds light on the interactions between various poisons and different catalysts, which is significant to abate NOx emissions for non‐electric industries.
Cyclophilin D as a potential therapeutic target of liver ischemia/reperfusion injury by mediating crosstalk between apoptosis and autophagy
Authors: Yang Mengjiao , Wang Zhihui , Xie Jin , Reyad‐ul‐Ferdous Md. , Li Siying , Song Yongfeng 
Published: June 2023

AbstractBackgroundLiver ischemia/reperfusion (I/R) injury is a complex and multifactorial pathophysiological process. It is well recognized that the membrane permeability transition pore (mPTP) opening of mitochondria plays a crucial role in cell death after I/R injury. Cyclophilin D (CypD) is a critical positive regulator of mPTP. However, the effect of CypD on the pathogenesis of liver I/R injury and whether CypD is a potential therapeutic target are still unclear.MethodsWe constructed liver‐specific CypD knockout and AAV8‐peptidyl prolyl isomerase F (PPIF) overexpression mice. Then, a 70% liver I/R injury model was established in mice, with 90 min of ischemia and 6 h of reperfusion. The liver function was detected by the level of serum glutamic pyruvic transaminase (alanine transaminase) and glutamic oxaloacetic transaminase (aspartate aminotransferase), the liver damage score and degree of necrosis were measured by hematoxylin and eosin (H&E) staining of liver tissues. Reactive oxygen species (ROS) staining, apoptosis, and autophagy‐related molecules were used to detect apoptosis and autophagy during liver I/R.ResultsThe liver‐specific knockout of CypD alleviated necrosis and dysfunction in liver I/R injury, by reducing the excessive production of ROS, and inhibiting cell apoptosis and autophagy. On the contrary, overexpression of CypD exacerbated I/R‐induced liver damage.ConclusionWe found that the downregulation of CypD expression alleviated liver I/R injury by reducing apoptosis and autophagy through caspase‐3/Beclin1 crosstalk; in contrast, the upregulation of CypD expression aggravated liver I/R injury. Therefore, interfering with the expression of CypD seems to be a promising treatment for liver I/R injury.
Photocatalyzed (3+2) Cycloaddition for the Dearomatization of Electron‐Poor Arenes under Flow Conditions
Authors: Faye Youssou , Rkein Batoul , Bigot Antoine , Lequeux Thierry , Legros Julien , Chataigner Isabelle 
Published: June 2023

AbstractThe photocatalyzed dearomative reaction between various electron‐deficient aromatic compounds and a non‐stabilized azomethine ylide is successfully performed in a flow system. Whereas the use of supported eosin as organic photocatalyst exhibits limited efficiency, turning to the soluble Rose Bengal allows to transform a broad range of substrates from hetarenes (indole, benzofuran, quinoline, pyridine) to naphthalenes and benzenes. This photocatalyzed (3+2) dearomative cycloaddition under green light irradiation provides a simple and efficient access to tridimensional pyrrolidino scaffolds with a tetrasubstituted carbon center at ring junction and can be performed in the friendly ethyl acetate. Computational studies support the mechanism involving azomethine ylide as reactive species toward the electron‐poor arene.
Harnessing Pillar[5]arene Host–Guest Complexation To Improve pH Stability and Affect Enzymatic Degradation of the Anticancer Prodrug Capecitabine: A 19F NMR Study
Authors: Horin Inbar , Slovak Sarit , Cohen Yoram 
Published: June 2023

AbstractCancer is a global health problem, and supramolecular chemotherapy is emerging as a novel strategy to battle the disease. Here, we first evaluated the thermodynamic and kinetic stability of the complexes formed between several water‐soluble per‐substituted pillar[5]arene derivatives and capecitabine (1), a widely used oral chemotherapeutic prodrug. The exchange rate was studied, for the first time in pillararene chemistry, by the 19F guest exchange saturation transfer (GEST) NMR technique. Importantly, when we evaluated the effect of complexation on the characteristics of 1, we found that the complexation of 1 with such pillar[5]arene hosts increased capecitabine stability at acidic pH very significantly and slowed its enzymatic degradation by the carboxylesterase enzyme in a manner that depended on the host. These interesting findings could have implications on the clinical use of this heavily used prodrug and might affect the management of cancer patients.
Serial Polarization Transfer by Combination of Cross‐Relaxation and Rotational Resonance for Sensitivity‐Enhanced Solid‐State NMR
Authors: Biedenbänder Thomas , Bensons Edvards R. , Corzilius Björn 
Published: June 2023

AbstractMethods which induce site‐specificity and sensitivity enhancement in solid‐state magic‐angle spinning NMR spectroscopy become more important for structural biology due to the increasing size of molecules under investigation. Recently, several strategies have been developed to increase site specificity and thus reduce signal overlap. Under dynamic nuclear polarization (DNP) for NMR signal enhancement, it is possible to use cross‐relaxation transfer induced by select dynamic groups within the molecules which is exploited by SCREAM‐DNP (Specific Cross Relaxation Enhancement by Active Motions under DNP). Here, we present an approach where we additionally reintroduce the homonuclear dipolar coupling with rotational resonance (R2) during SCREAM‐DNP to further boost the selectivity of the experiment. Detailed analysis of the polarization buildup dynamics of 13C‐methyl polarization source and 13C‐carbonyl target in 2‐13C‐ethyl 1‐13C‐acetate provides information about the sought‐after and spurious transfer pathways. We show that dipolar‐recoupled transfer rates greatly exceed the DNP buildup dynamics in our model system, indicating that significantly larger distances can be selectively and efficiently hyperpolarized.
Cobalt Oxide Arrays Anchored to Copper Foam as Efficient Binder‐free Anode for Lithium Ion Batteries
Authors: Liu Hangning , Liu Runmeng , Ma Yingjun , Wang Lin , Sun Changhui , Xu Tong , Liu Haidong , Wang Jie 
Published: June 2023

AbstractThe development of lithium‐ion batteries with simplified assembling steps and fast charge capability is crucial for current battery applications. In this study, we propose a simple in‐situ strategy for the construction of high‐dispersive cobalt oxide (CoO) nanoneedle arrays, which grow vertically on a copper foam substrate. It is demonstrated that this nanoneedle CoO electrodes provide abundant electrochemical surface area. The resulting CoO arrays directly act as binder‐free anodes in lithium‐ion batteries with the copper foam functioning as the current collector. The highly‐dispersed feature of the nanoneedle arrays enhances the effectiveness of active materials, leading to outstanding rate capability and superior long‐term cycling stability. These impressive electrochemical properties are attributed to the highly‐dispersed self‐standing nanoarrays, the advantages of binder‐free constituent, and the high exposed surface area of the copper foam substrate compared to copper foil, which enrich active surface area and facilitate charge transfer. The proposed approach to prepare binder‐free lithium‐ion battery anodes streamlines the electrode fabrication steps and holds significant promise for the future development of the battery industry.
An 18‐bit 1‐GS/s time interleaved analog‐to‐digital converter with timing skew calibration based on an adaptive genetic algorithm
Authors: Zhao Jiaqing , Zhang Jianwei , Zhang Yang , Liu Cheng , Xi Zhennan , Luo Xiangdong 
Published: June 2023

SummaryA foreground calibration method for timing skews of the time interleaved analog‐to‐digital converter (TIADC) system is proposed in this paper. In this method, the adaptive genetic algorithm (AGA) is used to replace the traditional least mean square (LMS) method to detect the timing skews, and the variable delay lines are used to calibrate the timing skews. This method can accomplish the detection and calibration of positive and negative timing skews, and the reference channels are not required. In addition, compared with other methods, this method has higher detection speed and detection accuracy. In this paper, a four‐channel 18‐bit 1‐GS/s TIADC system is modeled, and the performance of the proposed method is further verified. The results show that the convergence speed and the calibration accuracy of this method are higher, the signal‐to‐noise ratio (SNR) of the TIADC system is improved by 65.9 dB after calibration, and this method is also effective when the frequency of the input signal is close to the Nyquist frequency.
The role of spatial structure in at‐risk metapopulation recoveries
Authors: Wilson Kyle L. , Sawyer Alexandra C. , Potapova Anna , Bailey Colin J. , LoScerbo Daniella , Sweeney‐Bergen Elissa K. , Hodgson Emma E. , Pitman Kara J. , Seitz Karl M. , Law Lauren K. , Warkentin Luke , Wilson Samantha M. , Atlas William I. , Braun Douglas C. , Sloat Matthew R. , Tinker M. Tim , Moore Jonathan W. 
Published: June 2023

AbstractMetapopulations are often managed as a single contiguous population despite the spatial structure underlying their local and regional dynamics. Disturbances from human activities can also be spatially structured with mortality impacts concentrated to just a few local populations among the aggregate. Scale transitions between local and regional processes can generate emergent properties whereby the whole system can fail to recover as quickly as expected for an equivalent single population. Here, we draw on theory and empirical case studies to ask: what is the consequence of spatially structured ecological and disturbance processes on metapopulation recoveries? We suggest that exploring this question could help address knowledge gaps for managing metapopulations including: Why do some metapopulations recover quickly while others remain collapsed? And, what risks are unaccounted for when metapopulations are managed at aggregate scales? First, we used model simulations to examine how scale transitions among ecological and disturbance conditions interact to generate emergent metapopulation recovery outcomes. In general, we found that the spatial structure of disturbance was a strong determinant of recovery outcomes. Specifically, disturbances that unevenly impacted local populations consistently generated the slowest recoveries and highest conservation risks. Ecological conditions that dampened metapopulation recoveries included low dispersal, variable local demography, sparsely connected habitat networks, and spatially and temporally correlated stochastic processes. Second, we illustrate the unexpected challenges of managing metapopulations by examining the recoveries of three USA federally listed endangered species: Florida Everglade snail kites, California and Alaska sea otters, and Snake River Chinook salmon. Overall, our results show the pivotal role of spatial structure in metapopulation recoveries whereby the interplay between local and regional processes shapes the resilience of the whole system. With this understanding, we provide guidelines for resource managers tasked with conserving and managing metapopulations and identify opportunities for research to support the application of metapopulation theory to real‐world challenges.
Economic evaluation of web‐based guided self‐help cognitive behavioral therapy‐enhanced for binge‐eating disorder compared to a waiting list: A randomized controlled trial
Authors: Melisse Bernou , Blankers Matthijs , van den Berg Elske , de Jonge Margo , Lommerse Nick , van Furth Eric , Dekker Jack , de Beurs Edwin 
Published: June 2023

AbstractIntroductionThe aim is to perform an economic evaluation alongside a randomized controlled trial comparing guided self‐help cognitive behavioral therapy‐enhanced (CBT‐E) for binge‐eating disorder (BED) to a waiting list control condition.MethodsBED patients (N = 212) were randomly assigned to guided self‐help CBT‐E or the 3‐month waiting list. Measurements took place at baseline and the end‐of‐treatment. The cost‐effectiveness analysis was performed using the number of binge‐eating episodes during the last 28 days as an outcome indicator according to the eating disorder examination. A cost‐utility analysis was performed using the EuroQol‐5D.ResultsThe difference in societal costs over the 3 months of the intervention between both conditions was €679 (confidence interval [CI] 50–1330). The incremental costs associated with one incremental binge eating episode prevented in the guided self‐help condition was approximately €18 (CI 1–41). From a societal perspective there was a 96% likelihood that guided self‐help CBT‐E led to a greater number of binge‐eating episodes prevented, but at higher costs. Each additional quality‐adjusted life year (QALY) gained was associated with incremental costs of €34,000 (CI 2494–154,530). With a 95% likelihood guided self‐help CBT‐E led to greater QALY gain at higher costs compared to waiting for treatment. Based on the National Institute for Health and Clinical Excellence willingness‐to‐pay threshold of €35,000 per QALY, guided self‐help CBT‐E can be considered cost‐effective with a likelihood of 95% from a societal perspective.DiscussionGuided self‐help CBT‐E is likely a cost‐effective treatment for BED in the short‐term (3‐month course of treatment). Comparison to treatment‐as‐usual is recommended for future research, as it enables an economic evaluation with a longer time horizon.Public SignificanceOffering treatment remotely has several benefits for patients suffering from binge‐eating disorders. Guided self‐help CBT‐E is an efficacious and likely cost‐effective treatment, reducing binge eating and improving quality‐of‐life, albeit at higher societal costs.
Copper‐Catalyzed Coupling Reaction of Secondary Alkyl 2‐Pyridinesulfonates with Alkyl Lithium‐Based Reagents
Authors: Sato Yuta , Osada Akito , Ogawa Narihito , Kobayashi Yuichi 
Published: June 2023

AbstractThe Cu(OTf)2‐catalyzed alkyl–alkyl coupling reaction of a secondary substrate MeCH(OSO2Py)CH2CH2C6H4(4‐OMe) with a nBuLi‐based reagent prepared by transmetalation with MgBr2 ⋅ THF3 in THF produced a coupling product in 74 % yield. The use of soluble MgBr2 ⋅ THF3 in THF was required for this reaction. This method was applied to sBuLi and Ph(CH2)4Li. In contrast, transmetalation of MeLi with soluble MgCl2 ⋅ THF2 in THF produced the Me reagent, which was reactive for the coupling reaction. The reaction proceeded with inversion of the stereogenic carbon. Furthermore, (S)‐14‐methyloctadecan‐2‐one, a sex pheromone produced by lichen moths, was synthesized.
Digital colorimetric sensing for real‐time gas monitoring for smart green energy system
Authors: Cho Hui Hun , Dutta Riya , Kwak Jang‐Kyun , Moon Changgyun , Kim Min‐Jae , Suh Su‐Jeong , Kim Dong‐Hwan , Lee Jung Heon , Kim Sunkook 
Published: June 2023

AbstractIn this study, we demonstrate that a digital colorimetric sensor platform can transform a conventional energy system, such as gas‐insulated switchgear (GIS) into a smart green energy system. Our sensor platform consists of a colorimetric sensor film (CSF), an array of silicon photodiodes, and a low‐power‐driven fiber optical photodiode with a wireless communication protocol integrated into an information network. The photodiode measures the transmitted light of the color‐variable CSF when exposed to sulfur dioxide (SO2) gas, a decomposition by‐product of the sulfur hexafluoride (SF6) gas in GIS. We report the electrical photocurrent measurement through the CSF can measure the concentration of SO2 gas via remote and real‐time monitoring and shows a comparable behavior to UV–Vis absorption measurement. The limit of detection of the sensor, 0.78 ppm is sufficient to analyze the GIS insulation deterioration allowing green energy systems.image
Application of central composite design and response surface methodology for the study of extraction of gentian violet dye in aqueous solution by polystyrene membrane modified with oleic acid
Authors: AitAli Salima , Ziani Salima , Yahiaoui Idris , Brahmi Aghilas , Boudrahem Farouk , Aissani‐Benissad Farida 
Published: June 2023

AbstractThe present study is interested in removal of a cationic dye gentian violet (GV) using a polystyrene membrane (PS) activated with oleic acid (OA). These innovative membranes were developed by using PS as the base polymer and OA as extractant. The best matrix obtained was characterized by using Fourier transform infrared spectroscopy (FTIR) and x‐ray diffraction (XRD), and then applied in the extraction of a cationic GV dye. The effects of an extraction ratio (OA/PS) in the PS‐AO matrix, initial GV dye concentration ([GV]0), and pH of the solution were studied in a batch reactor. The thermodynamic parameters (, , and ) have been calculated. Therefore, the GV extraction onto the PS‐OA matrix is an exothermic and spontaneous process. In addition, the slop method confirms that the chemical formula of the extracted OA‐GV complex is GV‐RHR. The central composite design (CCD) was used to determine the conditions of each experimental run, and extraction optimization was achieved using response surface methodology (RSM). The results showed that the quadratic regression model was statistically significant (0.9994), and the parameters studied had a profound effect on the extraction efficiency. The optimum GV extraction efficiency of 99% was achieved at an extractant ratio of 1, pH of 8, and [GV]0 of 10 mg L−1. The findings of the current study reveal that PS‐AO matrix is an advantageous and effective membrane for the extraction of GV from aqueous solutions, both environmentally and economically, it can be regenerated and used up to five times.
Economic and environmental and energy investigation and reliability evaluation of renewable energy hybrid system
Authors: Chammam Abdeljelil , Albaker Abdullah , Alghamdi Mohammed I. , Al‐Kharsan Ibrahim H. , Demin Al‐Khafaji Ali Hussein , Aladdin Morteza 
Published: June 2023

AbstractToday, using systems based on renewable resources is a suitable alternative to fossil fuels. However, due to problems such as the lack of access in all the times needed to supply cargo and high‐investment cost, it has not been well‐received. In this research, in addition to maintaining the technical specifications and increasing the reliability of the system due to the addition of the hydroelectric power plant to other wind and solar systems, it has been tried to use biodiesel fuel (biofuel) as an alternative to fossil fuel in the diesel generator. To identify the most economical combination of the system with the application of social costs and the limit of pollutant and greenhouse gas emission in independent mode with the help of Homer software. the results showed that adding biodiesel to the designed system, the investment costs will increase by $282,038, which has a direct impact on the cost of energy and causes an increase of 0.0115 $/kWh. While the use of biodiesel reduces the emission of carbon dioxide by 28,947 kg/year.
The carrying capacity of the seas and oceans for future sustainable food production: Current scientific knowledge gaps
Authors: van der Meer Jaap , Callier Myriam , Fabi Gianna , van Hoof Luc , Nielsen J. Rasmus , Raicevich Saša 
Published: June 2023

AbstractThe expected increase in global food demand, as a consequence of a rising and wealthier world population, and an awareness of the limits and drawbacks of modern agriculture, has resulted in a growing attention to the potential of the seas and oceans to produce more food. The capture production of presently exploited marine fish stocks and other species has more or less reached its maximum and can only be slightly improved by better management. This leaves four alternative options open to increase marine food production: (1) manipulating the entire food web structure via removal of high trophic level species to allow an increasing exploitation of low trophic level species, (2) harvesting so far unexploited stocks, such as various fish species from the mesopelagic zone of the ocean or the larger zooplankton species from polar regions, (3) low‐trophic mariculture of seaweeds and herbivorous animals, and (4) restoration of impoverished coastal ecosystems or artificially increasing productivity by ecological engineering. In this paper, we discuss these four options and pay attention to missing scientific knowledge needed to assess their sustainability. To assess sustainability, it is a prerequisite to establish robust definitions and assessments of the biological carrying capacity of the systems, but it is also necessary to evaluate broader socio‐economic and governance sustainability.
School‐based interventions on Mpox: A scoping review
Authors: Amzat Jimoh , Kanmodi Kehinde K. , Aminu Kafayat , Egbedina Eyinade A. 
Published: June 2023

AbstractBackground and AimsThe 2022 multicountry mpox outbreak necessitated the declaration of mpox as a public health emergency. This is the first time a wide mpox spread and human‐to‐human transmission are recorded in several countries outside West and Central Africa. The outbreak reveals a strong need for wider intervention to increase awareness and control measures on mpox, especially in schools. This scoping review aims to summarize the existing evidence concerning school‐based interventions on mpox globally.MethodsThe review methodology was based on the Arksey and O'Malley guidelines and it was reported in strict adherence with the PRISMA‐ScR checklist. Ten databases were searched to retrieve literature relevant to the review topic. Thereafter, the retrieved literature were deduplicated and screened for inclusion into the review based on a set of eligibility criteria. Only one journal paper, a short communication on the national monkeypox outbreak in England, satisfied the selection criteria and was included in the review. Data extracted from the included paper were collated, summarized, and presented.ResultsThe paper described how suspected cases of mpox infection were managed in some school settings through vaccination and self‐isolation approaches and revealed a low (11%) mpox vaccination uptake rate in school‐setting. The preventive methods adopted, such as the exclusion of exposed persons from school (in three school settings) and separation of those exposed those who were not in contact with the affected persons (one school setting), played a major role in the low transmission rate reported. This review also found a huge dearth of literature on school‐based interventions on mpox despite its global spread.ConclusionWith the call for a multisectoral approach in the fight against mpox, it pays to leverage on the potential of school settings in public health actions against mpox.