bluuebunny/crossref_metadata_2025_split huggingface dataset:
Values and preferences of health care professionals, policy‐makers, patients and family members regarding recommendations of adapted physical restraint guidelines in critical care: A survey research
Authors: Cui Nianqi , Gan Xiuni , Huang Sufang , Chu Zhe , Chen Dandan , Zhang Yuping , Lan Meijuan , Jin Jingfen 
Published: July 2023

AbstractBackgroundThe values and preferences of stakeholders are crucial in the development of guidelines.AimThe aim of this study was to investigate stakeholders’ values and preferences regarding draft recommendations for adapted physical restraint guidelines in China.Study designThis survey research was carried out at four university‐affiliated comprehensive hospitals based in the eastern, central, western, and north eastern zones of China from January 5‐30, 2022. A 48‐item self‐report questionnaire was distributed, and values and preferences were assessed on a 10‐point Likert scale. One‐way ANOVA was used to compare values and preference scores among stakeholders. As effect‐size measures, partial η2 and Cohen's f values are reported for ANOVA results.ResultsA total of 1155 stakeholders were enrolled in the study. The mean value and preference scores were higher than seven for 46 draft recommendations. There was either no significant difference in the values and preferences of the stakeholders for the draft recommendations or there was a significant difference (p values ranged from <0.001 ∼ .048), but the effect size was small or very small (partial η2 value ranged from 0.011 ∼ .044; Cohen's f value ranged from 0.101 ∼ .214). The mean scores of patients for items related to cyber therapy and early tracheotomy were 6.84 and 6.60, respectively, which were lower than those of family members, policy‐makers, and health care professionals and were statistically significant (p < 0.001). The partial η2 and Cohen's f values of the effect size were 0.083/0.062 and 0.302/0.256, respectively, which indicated that the differences were moderate.ConclusionThese recommendations were in line with the values and preferences of stakeholders. Patients were more supportive of implementing cyber therapy or hypnosis for pain management but did not support early tracheotomy to reduce the duration of mechanical ventilation. Guideline panels could use value and preference information to revise and endorse recommendations of adapted physical restraint guidelines in critical care.Relevance to Clinical PracticePractitioners should implement recommendations based on the values and preferences of stakeholders.
The landscape is a trap: Duck decoys as multispecies atmospheres of deception and betrayal
Authors: van Heijgen Eugenie , Driessen Clemens , Turnhout Esther 
Published: July 2023

AbstractDuck decoys are trapping devices designed to catch ducks. From the fourteenth century onwards, duck decoys emerged in riverine lowlands in northwestern Europe. Their operation is based on a rigorously maintained physical structure with a woodland that encloses a water body with protruding extensions called pipes, which end in nets and are surrounded by reed screens. Catching ducks in these places requires a complex interplay between different groups of ducks, a dog, and a human decoyman who together are enmeshed in what becomes a deeply deceptive landscape. This paper explores duck decoys in the Netherlands as relational, situated and co‐designed multispecies atmospheres. Through ethnographic descriptions of field visits, interviews and by drawing on historical accounts, we trace how inter‐ and intraspecies relations and behaviours are interpreted in terms of deception, betrayal, trust and curiosity. The varying interpretations of behaviours and the more‐than‐human knowledges at play reflect the essentially elusive character of the duck decoy. Especially when facing the environmental challenges of the Anthropocene, duck decoys and the ambiguous relations that were until recently maintained in them, encourage us to consider the historical trapping and hunting landscapes as places made by multispecies atmospheres. Even though these atmospheres and the intimate collectives of human and more‐than‐human lives have become increasingly fragile, their afterlives resonate through the changing character of the riverine landscape and its various waterfowl, as well as practices of knowing and conserving biodiversity.
p63 immunoexpression in hair follicles of normal and alopecia X‐affected skin of Pomeranian dogs
Authors: Della Salda Leonardo , Bongiovanni Laura , Massimini Marcella , Romanucci Mariarita , Vercelli Antonella , Colosimo Alessia , Di Matteo Ramona , Defourny Sabrina Vanessa Patrizia 
Published: July 2023

AbstractBackgroundAlopecia X in Pomeranians is caused by a hair cycle deregulation, associated with downregulation of key regulatory genes of the Wnt and Shh pathways, and stem‐cell markers. However, the pathogenesis remains unclear. p63 is an important transcription factor correlated with the aforementioned hair cycle modulating genes.Hypothesis/ObjectivesThe aim of this study was to highlight possible changes of p63 immunohistochemical expression within the hair follicles in canine alopecia X compared with normal skin.AnimalsSkin biopsies from 19 alopecia X‐affected and six control Pomeranians were analysed.Materials and MethodsSerial histological sections of skin biopsies harbouring anagen, telogen and kenogen hair follicles were immunohistochemically evaluated for differences in p63 expression in the affected and control samples.ResultsDogs with alopecia X had a significantly decreased immunoexpression of p63 in telogen and kenogen hair follicles.Conclusions and Clinical RelevanceThe decrease of p63 immunoexpression observed in canine alopecia X suggests an involvement of p63 in hair cycle.
Reviewer Acknowledgements for International Journal of Social Science Studies, Vol. 11, No. 4
Authors: Young James 
Published: July 2023

International Journal of Social Science Studies (IJSSS) would like to acknowledge the following reviewers for their assistance with peer review of manuscripts for this issue. Many authors, regardless of whether IJSSS publishes their work, appreciate the helpful feedback provided by the reviewers. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Each of the reviewers listed below returned at least one review for this issue.Reviewers for Volume 11, Number 4Aurora Pestaño, University of San Jose Recoletos (USJR), PhilippinesDaniel Tia, University of Félix Houphouët-Boigny Abidjan, GRATHEL , Cote d’Ivoire (Ivory Coast)Encarnación ABAD ARENAS, National University of Distance Education (UNED), SpainFahri ÖZSUNGUR, Adana Science and Technology University, TurkeyJean Patrick Mve, Hohai University-China, CameroonJehu Onyekwere Nnaji, University of Naples II,Italy and Globe Visions Network Italy, ItalyJulia M. Mack, Gannon University, USAMd. Nasir Uddin, Prime Minister’s Office, BangladeshMei-Ling Lin, National Open University, TaiwanMOHD NORAZMI BIN NORDIN, Universiti Kebangsaan Malaysia, MalaysiaNAZIAH ABD. KADIR, Universiti Selangor, MalaysiaSana Ali, Allama Iqbal Open University, Islamabad, PakistanYao Jingwu, Business School of Yulin Normal University, China James YoungEditorial AssistantOn behalf of,The Editorial Board of International Journal of Social Science StudiesRedfame Publishing9450 SW Gemini Dr. #99416Beaverton, OR 97008, USAURL: http://ijsss.redfame.com
Design of Next-Generation Automotive Systems: Challenges and Research Opportunities
Authors: Panchal Jitesh H. , Wang Ziran 
Published: July 2023

Abstract
The automotive industry is undergoing a massive transformation, driven by the mega-trends of “CASE”: connected, autonomous, shared, and electric. These trends are affecting the nature of automobiles, both internally and externally. Internally, the transition from internal combustion engines (ICE) to electric drive-trains has resulted in a shift from hardware-centric vehicles to software-defined vehicles (SDVs), where software is increasingly becoming the dominant asset in the automotive value chain. These trends are leading to new design challenges such as how to manage different configurations of design, how to decouple the design of software and services from hardware, and how to design hardware to allow for upgrades. Externally, automobiles are no longer isolated products. Instead, they are part of the larger digital ecosystem with cloud connectivity. Vehicle usage data are increasingly connected with smart factories, which create new opportunities for agile product development and mass customization of features. The role of the human driver is also changing with increasing levels of autonomy features. In this paper, the authors discuss the ongoing transformation in the automotive industry and its implications for engineering design. The paper presents a road map for engineering design research for next-generation automotive applications.
Application of classic grounded theory in nursing studies: a qualitative systematic review protocol
Authors: Connor Justine , Flenady Tracy , Dwyer Trudy , Massey Debbie 
Published: July 2023

IntroductionClassic grounded theory (CGT) is a valuable method for nursing research, but the application of CGT methodology in nursing studies has not been specifically investigated. With the increasing use of CGT in nursing research, attention is now focusing on the quality of studies using this methodology. In this systematic review, we aim to develop an understanding of the application of CGT methodology, specifically appraising the quality of the methodology’s application in the field of nursing research.Methods and analysisThe reporting of this review will be guided by the Preferred Reporting Items for Systematic and Meta-Analysis guidelines statement and data synthesis guided by the Synthesis Without Meta-analysis guideline. Publications will be uploaded to Rayyan. The quality of each article will be assessed using the Critical Appraisals Skills Programme qualitative research appraisal tool. Analysis of the selected studies will be performed using the Guideline for Reporting and Evaluating Grounded Theory Research Studies, explicitly the CGT guiding principles.Ethics and disseminationEthical approval is not required because only secondary data will be used in this review. The results of the final study will be published in a peer-reviewed open-access journal.PROSPERO registration numberCRD42021281103.
Development and psychometric properties of a self-assessed knowledge questionnaire for caregivers of people with multiple sclerosis (CareKoMS): a cross-sectional study
Authors: Podda Jessica , Tacchino Andrea , Verri Anna , Battaglia Mario Alberto , Brichetto Giampaolo , Ponzio Michela 
Published: July 2023

ObjectivesKnowledge about multiple sclerosis (MS) is crucial for those who provide care and support as caregivers. However, despite the key benefits of acquiring relevant information to properly assume the caregiving role, caregivers’ knowledge of MS is poorly investigated. The aim of this study was to develop and validate the Caregivers’ Knowledge of Multiple Sclerosis (CareKoMS), a self-assessed questionnaire, to test MS knowledge in caregivers of people with MS.DesignCross-sectional study.SettingItaly.ParticipantsTwo-hundred caregivers (female: 49%) were asked to self-administer the 32-item CareKoMS questionnaire; they had a median age of 60 years (IQR: 51–68 years) and a medium–high educational level (36.5% primary school and 63.5% high school/university). Item analysis using item difficulty index, item discrimination index, Kuder-Richardson-20 coefficient and item-total correlation were assessed. Once excluding less useful items, reliability, floor and ceiling effects and construct validity were calculated on the 21-item CareKoMS final version.ResultsPsychometric evaluation indicates that the 21-item CareKoMS was a good questionnaire with no ceiling or floor effects registered. Internal consistency was satisfactory and acceptable as indicated by the mean value of 0.74 of Kuder-Richardson-20. No ceiling or floor effects have been observed. Interestingly, educational level and disease duration correlated with MS knowledge.ConclusionCareKoMS is a valid self-assessed questionnaire on MS knowledge for caregivers that may be used in clinical practice and research. Assessing knowledge of MS among caregivers is essential to facilitate their caregiving role and thus decrease the burden of disease management.
Applying an equity lens to hospital safety monitoring: a critical interpretive synthesis protocol
Authors: Goldman Joanne , Lo Lisha , Rotteau Leahora , Wong Brian M , Kuper Ayelet , Coffey Maitreya , Rawal Shail , Alfred Myrtede , Razack Saleem , Pinard Marie , Palomo Michael , Trbovich Patricia 
Published: July 2023

IntroductionHospital safety monitoring systems are foundational to how adverse events are identified and addressed. They are well positioned to bring equity-related safety issues to the forefront for action. However, there is uncertainty about how they have been, and can be, used to achieve this goal. We will undertake a critical interpretive synthesis (CIS) to examine how equity is integrated into hospital safety monitoring systems.Methods and analysisThis review will follow CIS principles. Our initial compass question is: How is equity integrated into safety monitoring systems? We will begin with a structured search strategy of hospital safety monitoring systems in CINAHL, EMBASE, MEDLINE and PsycINFO for up to May 2023 to identify papers on safety monitoring systems generally and those linked to equity (eg, racism, social determinants of health). We will also review reference lists of selected papers, contact experts and draw on team expertise. For subsequent literature searching stages, we will use team expertise and expert contacts to purposively search the social science, humanities and health services research literature to support the development of a theoretical understanding of our topic. Following data extraction, we will use interpretive processes to develop themes and a critique of the literature. The above processes of question formulation, article search and selection, data extraction, and critique and synthesis will be iterative and interactive with the goal to develop a theoretical understanding of equity in hospital monitoring systems that will have practice-based implications.Ethics and disseminationThis review does not require ethical approval because we are reviewing published literature. We aim to publish findings in a peer-reviewed journal and present at conferences.
Adjuvant Lipoic acid Injection in Sepsis treatment in China (ALIS study): protocol for a randomised, single-blind, placebo-controlled trial
Authors: Hu Linhui , Zhou Xinjuan , Huang Jinbo , He Yuemei , Wu Quanzhong , Huang Xiangwei , Wu Kunyong , Wang Guangwen , Li Sinian , Chen Xiangyin , Chen Chunbo 
Published: July 2023

IntroductionSepsis is a life-threatening immune disorder resulting from an dysregulated host response to infection. Adjuvant therapy is a valuable complement to sepsis treatment. Lipoic acid has shown potential in attenuating sepsis-induced immune dysfunction and organ injury in vivo and in vitro studies. However, clinical evidence of lipoic acid injection in sepsis treatment is lacking. Hence, we devised a randomised controlled trial to evaluate the efficacy and safety of lipoic acid injection in improving the prognosis of sepsis or septic shock patients.Methods and analysisA total of 352 sepsis patients are planned to be recruited from intensive care units (ICUs) at eight tertiary hospitals in China for this trial. Eligible participants will undergo randomisation in a 1:1 ratio, allocating them to either the control group or the experimental group. Both groups received routine care, with the experimental group also receiving lipoic acid injection and the control group receiving placebo. The primary efficacy endpoint is 28-day all-cause mortality. The secondary efficacy endpoints are as follows: ICU and hospital mortality, ICU and hospital stay, new acute kidney injury in ICU, demand and duration of life support, Sequential Organ Failure Assessment (SOFA)/Acute Physiology and Chronic Health Evaluation II (APACHE II) and changes from baseline (ΔSOFA/ΔApache II), arterial blood lactate (LAC) and changes from baseline (ΔLAC), blood procalcitonin, high-sensitivity C-reactive protein, interleukin-2 (IL-2), IL-4, IL-6, IL-10, tumour necrosis factor-α (TNF-α) and interferon-γ (IFN-γ) and changes from baseline on day 1 (D1), D3, D5 and D7. Clinical safety will be assessed through analysis of adverse events.Ethics and disseminationThe study was approved by the Ethics Committee of Maoming People’s Hospital (approval no. PJ2020MI-019-01). Informed consent will be obtained from the participants or representatives. The findings will be disseminated through academic conferences or journal publications.Trial registrationChiCTR2000039023.
Is a sedentary lifestyle a leading causal factor of obesity and distress in type 2 diabetes? A cross-sectional study in low-socioeconomic areas of Karachi, Pakistan
Authors: Sharif Sana , Sharif Hina , Rehman Junaid , Fatima Zoya 
Published: July 2023

BackgroundWorldwide, the burden of diabetes with obesity as comorbidity has intensely increased. Even though sedentary behaviour is not favourable for a healthy lifestyle, some people still live a sedentary lifestyle. There is a dire need to report cases of sedentary behaviour in people with diabetes and obesity in the slums of Karachi, Pakistan.ObjectivesTo assess the association of obesity and distress with sedentary behaviour among individuals with diabetes in slums and the associated factors.MethodsThis institutional-based cross-sectional study was conducted in 38 slums in Karachi, Pakistan, to determine the association of sedentary behaviour with poor glycaemic control and demographic factors. Data from August to September 2022 were analysed, and inferences were drawn.ResultsAmong the studied population, out of 493 participants, 273 (55%) were female of age range 46–55 years 109 (22%) belonged to body mass index class-1 obesity 110 (22%), with hypertension 205 (42%), showed sedentary behaviour with low-socioeconomic settlements 299 (61%), and belong to Pathan ethnicity 153 (31%). More participants were married 337 (68%), had low-socioeconomic status 299 (61%) and had a positive family history of diabetes 242 (49%).ConclusionsThis study found that sedentary behaviour is significantly associated with the sociodemographic and clinical profile of patients with type 2 diabetes. It causes a long turn effect that can only result in uncontrolled and poor glycaemic control in diabetes and metabolic imbalance. The study can promote a physical-induced work setup and spread awareness among illiterate people for awareness of disease complications.
Incidence and outcome of perforations during medium vessel occlusion compared with large vessel occlusion thrombectomy
Authors: Schulze-Zachau Victor , Brehm Alex , Ntoulias Nikolaos , Krug Nadja , Tsogkas Ioannis , Blackham Kristine Ann , Möhlenbruch Markus A , Jesser Jessica , Cervo Amedeo , Kreiser Kornelia , Althaus Katharina , Maslias Errikos , Michel Patrik , Saliou Guillaume , Riegler Christoph , Nolte Christian H , Maier Ilko , Jamous Ala , Rautio Riitta , Ylikotila Pauli , Fargen Kyle M , Wolfe Stacey Q , Castellano Davide , Boghi Andrea , Kaiser Daniel P O , Cuberi Ani , Kirschke Jan S , Schwarting Julian , Limbucci Nicola , Renieri Leonardo , Al Kasab Sami , Spiotta Alejandro M , Fragata Isabel , Rodriquez-Ares Tania , Maurer Christoph Johannes , Berlis Ansgar , Moreu Manuel , López-Frías Alfonso , Pérez-García Carlos , Commodaro Christian , Pileggi Marco , Mascitelli Justin , Giordano Flavio , Casagrande Walter , Purves Cynthia P , Bester Maxim , Flottmann Fabian , Kan Peter T , Edhayan Gautam , Hofmeister Jeremy , Machi Paolo , Kaschner Marius , Weiss Daniel , Katan Mira , Fischer Urs , Psychogios Marios-Nikos 
Published: July 2023

BackgroundVessel perforation during thrombectomy is a severe complication and is hypothesized to be more frequent during medium vessel occlusion (MeVO) thrombectomy. The aim of this study was to compare the incidence and outcome of patients with perforation during MeVO and large vessel occlusion (LVO) thrombectomy and to report on the procedural steps that led to perforation.MethodsIn this multicenter retrospective cohort study, data of consecutive patients with vessel perforation during thrombectomy between January 1, 2015 and September 30, 2022 were collected. The primary outcomes were independent functional outcome (ie, modified Rankin Scale 0–2) and all-cause mortality at 90 days. Binomial test, chi-squared test andt-test for unpaired samples were used for statistical analysis.ResultsDuring 25 769 thrombectomies (5124 MeVO, 20 645 LVO) in 25 stroke centers, perforation occurred in 335 patients (1.3%; mean age 72 years, 62% female). Perforation occurred more often in MeVO thrombectomy (2.4%) than in LVO thrombectomy (1.0%,p<0.001). More MeVO than LVO patients with perforation achieved functional independence at 3 months (25.7% vs 10.9%,p=0.001). All-cause mortality did not differ between groups (overall 51.6%). Navigation beyond the occlusion and retraction of stent retriever/aspiration catheter were the two most common procedural steps that led to perforation.ConclusionsIn our cohort, perforation was approximately twice as frequent in MeVO than in LVO thrombectomy. Efforts to optimize the procedure may focus on navigation beyond the occlusion site and retraction of stent retriever/aspiration catheter. Further research is necessary in order to identify thrombectomy candidates at high risk of intraprocedural perforation and to provide data on the effectiveness of endovascular countermeasures.
Fibromyalgia and mortality: a systematic review and meta-analysis
Authors: Treister-Goltzman Yulia , Peleg Roni 
Published: July 2023

ObjectiveTo conduct a systematic review of the literature on the association between fibromyalgia and mortality and to pool the results in a meta-analysis.MethodsThe authors searched the PubMed, Scopus, and Web of Science databases using the key words ‘fibromyalgia’ and ‘mortality’ to identify studies that addressed an association between fibromyalgia and mortality. Original papers that assessed associations between fibromyalgia and mortality (all or specific causes) and provided an effect measure (hazard ratio (HR), standardised mortality ratio (SMR), odds ratio (OR)) quantifying the relationship between fibromyalgia and mortality were included in the systematic review. Of 557 papers that were initially identified using the search words, 8 papers were considered eligible for the systematic review and meta-analysis. We used a Newcastle-Ottawa scale to assess the risk of bias in the studies.ResultsThe total fibromyalgia group included 188 751 patients. An increased HR was found for all-cause mortality (HR 1.27, 95% CI 1.04 to 1.51), but not for the subgroup diagnosed by the 1990 criteria. There was a borderline increased SMR for accidents (SMR 1.95, 95% CI 0.97 to 3.92), an increased risk for mortality from infections (SMR 1.66, 95% CI 1.15 to 2.38), and suicide (SMR 3.37, 95% CI 1.52 to 7.50), and a decreased mortality rate for cancer (SMR 0.82, 95% CI 0.69 to 0.97). The studies showed significant heterogeneity.ConclusionsThese potential associations indicate that fibromyalgia should be taken seriously, with a special focus on screening for suicidal ideation, accident prevention, and the prevention and treatment of infections.