bluuebunny/crossref_metadata_2025_split huggingface dataset:
Physics-informed neural networks for prediction and physical interpretability analysis of key regional variables of ENSO
Authors: Chen Biao , Du Huadong , Pu Kang , Wang Shaodong , Sheng Zheng 
Published: March 2023

Abstract
This paper is the first to integrate the two scientific paradigms of the negative feedback dynamics mechanism of El Niño–Southern Oscillation (ENSO) and deep learning methods, and systematically studies the prediction method of key regional variables of ENSO. This paper mainly performed two activities: first, two physics-informed neural network methods are proposed to solve the ordinary differential equations (ODEs) of ENSO negative feedback theory, including classical physics-informed neural networks (PINNs) and variant-physics-informed Long Short-Term Memory (PILSTM) neural networks, and the novel defined physics-informed neural network loss function weights are optimized and balanced. Second, only 780 natural month-scale small datasets in the Coupled Model Intercomparison Project Phase 6 (CMIP6) model are used to improve the accuracy of correlative skills, and solve the problem of obvious decline in medium- and long-term correlative skills in the current air–ocean coupled dynamic prediction model. The results show that the research paradigms of the two physics-informed neural networks are an effective and complementary method in dealing with medium- and long-term prediction problems. Moreover, the PILSTM model based on recharge–discharge oscillator theory performed the best, and were better than the traditional delayed oscillator theory numerical operator method and the recharge–discharge oscillator theory numerical operator method. Meanwhile, the proposed method solved the delay problem in the recharge–discharge oscillator theory, indicating that the physics-informed neural networks learned the negative feedback dynamics mechanism of ENSO well, and effectively complemented the existing ENSO oscillator theory through the features learned from the training data, which help us to further comprehend the complex mechanism of ENSO events.
Effects of Carbon Policies on Demand Pricing of Forest Carbon Sequestration: A Review of High-Carbon Emission Enterprises in China
Authors: Yang Hong , Long Fei , Zhu Zhen , Pan Rui , Wang Danting , Yang Jun , Shen Yueqin 
Published: March 2023

Abstract
This study aimed to promote the reasonable pricing of forest carbon sinks and the development of the carbon market. In this study, we utilized four carbon emission-intensive enterprises in the thermal power, steel and chemical industries in Shanghai, Beijing, Guangdong, and Hubei provinces. Based on the marginal carbon emission reduction costs of the sample enterprises, the Rubinstein game model was used to calculate the demand price of forest carbon sinks of the sample enterprises; moreover, the cloud model was used to simulate the impact of policy changes on them. This showed that the demand price of forest carbon sinks for enterprises in different regions and industries is different and there are great differences under different policy scenarios. Notably, the proportion of carbon offset allowed by the government and the amount of carbon subsidies have a positive impact on the demand price of forest carbon sinks; contrastingly, the rate of carbon tax collection has a negative impact. Among them, the allowable offset ratio significantly influences it. We suggest adopting differentiated emission reduction policies, increasing the proportion of forest carbon sequestration offset, and transitioning from a single policy to a diversified comprehensive policy.
Analysis the immunoglobulin level in high risk pediatric Burkitt’s lymphoma treated with intensive chemotherapy combined with different doses of rituximab in real world
Authors: Huang Shuang , Li Ying , Sun Yixin , Peng Yaguang , Jin Ling , Yang Jing , Zhang Meng , Zhang Yonghong , Wang Xiaoling , Duan Yanlong 
Published: March 2023

Abstract
Background: Rituximab(R) added to chemotherapy(CT) prolongs survival among pediatric Burkitt’s lymphoma(BL). Data on its side effect in pediatric patients are limited. We aim to explore the therapeutic effect of different doses of R on children with BL in high-risk group and whether there is any difference in the level of immunoglobulin after treatment.
Methods: We retrospectively summarize clinical data with high risk group BL treated in Beijing Children’s Hospital(BCH), baseline characteristics, treatment outcomes and serum immunoglobulin (Ig) level in different time point (before CT, end of CT, 6 months after CT, 12 months after CT)were collected. We compared the efficacy of CT combined with different doses of R and the difference of immunoglobulin level after treatment. At the same time, monitor whether the children have repeated severe infection and hepatitis B virus reactivation after treatment in the study period.
Results: (1)baseline characteristics: 300 high risk group BL (256 boys,44 girls) were enrolled in this study, 300 patients were divided into 3 groups: standard CT group (R0, n=38), 6 doses of R+ CT group (R6 group, n=87) and 4 doses of R+ CT group (R4 group, n= 175). The 3-years EFS were 82%±4.9%, 91.9±2.5%, and 91.2±2.3% respectively. (2)The median level of Ig(before CT, end of CT, 6 months after CT, 12 months after CT): IgA level were 0.78g/L, 0.44g/L, 0.52g/L, and 0.69g/L. IgM level were 0.84g/L, 0.23g/L, 0.48g/L,and 0.7g/L. IgG level were 7.2g/L, 5.6g/L, 5.7g/L, and 6.6g/L. (3) Comparison the median Ig level after CT between R4 and R6 group(according to Ig level before chemotherapy, data was 1:1 matched, and 78 children were included in R4 and R6 group): IgA, IgM and IgG level in R4 group were all higher than that in R6 group after CT, and there was a statistical difference in the change trend between 2 groups in Ig A and IgM level.
Conclusion: In children with high risk BL, rituximab combined with intensive chemotherapy can significantly improve the efficacy. Immune reconstitution is usually 6 months after the end of chemotherapy. There was no difference with treatment outcomes in R6 and R4 group, but the serum immunoglobulin reconstitution is faster after treatment in R4 group, IgA and IgG levels return to normal earlier.
Green chemistry syntheses of different morphology novel nano-sized cobalt(II) supramolecular: as a precursor for the synthesis of cobalt(II) oxide nanoparticles, thermal, Hirshfeld surface analysis, and biological activities
Authors: Rahpeyma Masoumeh , SoltanianFard Mohammad Jaafar , Hayati Payam 
Published: March 2023

AbstractNano-structures of cobalt(II) metal-organic compound (Co-MOC) [Co(L)2(H2O)4] {1} (L = pyridine-3-carboxylic acid), have already been fabricated using two numerous experimental techniques which are including branched tube and sonochemical strategies. Besides the technique employed for1, an identical crystal structure was obtained. Scanning electron microscopy (SEM), powder X-Ray diffraction (PXRD), as well as Fourier transform infrared spectroscopy (FT-IR), were applied for the characterization of all compounds. Single-crystal X-Ray diffraction (SCXRD) analyses of1reveal which Co2+ions are 6-coordinated. Additionally, the temperature, time of reaction, the concentration of reactant, and sonication energy on the formation and ultimate morphology of compounds acquired by the sonochemical strategy are investigated. Ultimately, TGA (thermal gravimetric analyses), DTA (differential thermal analyses), as well as Hirshfeld surface analysis (HAS) of 1, were studied. Two strains of gram-negative Escherichi coli (E. coli) and gram-positive S. aureus) Staphylococcus aureus) was refined to the current compounds of1to determine their biological activities. These compounds exhibited adequate antibacterial activity within an abiotic environment.
Canine amnion membrane derived mesenchymal stem cells alleviate atopic dermatitis though TGF-β1 and IDO1
Authors: Kim MinSoo , Gong Dasom , Han Myounghee , Roh Kyounghwan , Koo Hojun , Lee Seounghee , Kang Kyung-Sun 
Published: March 2023

Abstract
Mesenchymal stem cells (MSCs) are a promising tool for treating immune disorders. However, the effect and mechanism of canine MSCs compared with other commercialized biologics for treating immune disorders have not been well studied. In this study, we investigated the characteristics and immunomodulatory effects of canine amnion membrane (cAM)-MSCs. We examined T lymphocytes from activated canine peripheral blood mononuclear cell (PBMC) proliferation. As a result, we confirmed that cAM-MSCs suppressed the proliferation capacity of T cells and cytotoxic activity. Moreover, we confirmed the therapeutic effect and mechanism of cAM-MSCs compared with oclacitinib, the most commonly used Janus kinase (JAK) inhibitor, as a treatment for canine atopic dermatitis (AD) using a mouse AD model. As a result, we confirmed that scores of dermatologic signs, tissue pathologic changes and inflammatory cytokines were significantly reduced by cAM-MSC treatment. In particular, cAM-MSCs were more effective than oclacitinib in the recovery of wound dysfunction and regulation of mast cell activity. Interestingly, subcutaneous injection of cAM-MSCs induced weight recovery, but oral administration of oclacitinib induced weight loss as a side effect. In addition, it was confirmed that the secretion of TGF-β1 and IDO by cAM-MSCs is directly involved in improving atopic dermatitis. In conclusion, this study suggests that cAM-MSCs can be developed as a safe canine treatment for atopic dermatitis without side effects through effective regeneration and immunomodulation.
Owner psychological characteristics predict dog behavioural traits
Authors: Clarke Harriet , Loftus Loni 
Published: March 2023

Abstract
There is extensive literature on the human-dog bond, less however on the role of owner psychological characteristics within this bond, and less still on how these might mediate dog behaviour. Accordingly, the aim of this study was to explore the relationship between owner levels of depression, anxiety and self-esteem and dog behaviour. Multiple linear regression was conducted to determine the predictive power of the psychological variables on dog behaviour using self-report. Conceptual content analysis was performed on three open questions to assess owner beliefs regarding their psychological influence on their dogs’ behaviour. 497 responses were collected. Anxiety and depression positively predicted increased levels of dog attachment and attention-seeking (p = < 0.001; p = 0.006), separation-related behaviour (p = < 0.001; p = < 0.001), stranger-directed aggression (p = < 0.001; p = < 0.001), stranger-directed fear (p = < 0.001; p = < 0.001), non-social fear (p = < 0.001; p = 0.01), dog-directed fear (p = 0.01; p = 0.01), touch sensitivity (p = < 0.001; p = < 0.001) and excitability (p = 0.004; p = < 0.001). Decreased self-esteem predicted dog non-social fear (p = 0.01). Fourteen themes were identified, including strong perceived bond, emotional dependency and anthropomorphism. Whilst only minimal within the vast interplay of factors impacted in canine ethology, owner psychological functioning plays a significant role in dog behaviour via numerous routes including interaction, emotion contagion and attachment. Understanding owner influence on dog behaviour can improve behaviour modification programmes, success of rehoming schemes, and improve wellbeing for both members of the human-dog dyad.
Cognitive and Economic Development
Authors: Gallup John Luke 
Published: March 2023

Abstract
Early childhood health conditions have large effects on the cognitive development, education and earnings of individuals. This paper assesses the impact of cognitive development on national economic development. Each risk factor for cognitive development also causes child mortality, making child survival a viable proxy for good cognitive development conditions. The cognitive development of current workers happened decades earlier when they were children. Child survival from a generation ago is one of the strongest correlates of economic growth in both low and high income countries. This evidence suggests that early cognitive development plays a major role in economic development.
One-Step Synthesis of 3D Nitrogen-doped Graphene Quantum Dots and Reduced Graphene Oxide Composites by a Hydrothermal Method for Supercapacitors Anodes
Authors: Gong Xiaobin , Yang Jingjing , Yao Kai , Li Yanan , Pan Gaofei , Ge Xin , Xing Ruiguang 
Published: March 2023

Abstract
This work reports a feasible method to fabricate a simple chemical functionalization of graphene oxide (GO) electrode, One-step hydrothermal synthesis of nitrogen-doped graphene quantum dots modified reduced graphene oxide (NGDQs/rGO2) using ammonium citrate and graphene oxide (GO) as raw materials. Ammonium citrate effectively acts as a nitrogen dopant cum reducing agent for graphene which remarkably enhances its electrochemical properties. Diffraction of X-rays (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), transmission electron microscope (TEM), X-ray photoelectron spectroscopy (XPS) were employed to characterize the structure and properties of the (NGDQs/rGO2), and the NGQDs/rGO2 was used as the electrode to test the electrochemical performance. According to the electrochemical test results, when the molar ratio of NGDQs to rGO is 1:2, the specific capacitance can reach 357 F/g at a current density of 1 A/g; after 1000 cycles, the capacitance retention rate is 82%. For comparison, under the same current density condition, the specific capacitance of the rGO electrode is only 74 F/g. Thus, the synthesized NGDQs/rGO2 using this simple, cost-effective, environment friendly method could be a potential candidate for high performance energy-storage applications.
WITHDRAWN: Data mining to identify diagnostic and prognostic markers in lung adenocarcinoma
Authors: Kong Kangle , Zhang Youping , He Mu , Sun Chenyu , Lowe Scott , Kim Na , Chu Rachel , Li Yaru , Zhu Wei , Rubalskii Evgenii , Zhao Bo , Yao Wenjian , Peng Shu 
Published: March 2023

Abstract
Background: Lung adenocarcinoma (LUAD), the most common type of lung cancers, is a leading cause of cancer-related death. Early diagnosis is essential to improve the outcome of LUAD, especially to reduce its mortality. This study aims to explore individual and regulatory network of mRNA, lncRNA and miRNA with diagnostic or prognostic value in LUAD.
Methods: Differentially expressed RNAs of LUAD based on intersection of The Cancer Genome Atlas (TCGA) and the Gene Expression Omnibus (GEO) databases were analyzed by bioinformatic methods.
Result: The competitive endogenous RNA (ceRNA) network was obtained with 40 differentially expressed (DE) mRNA nodes, 125 differentially expressed lncRNAs (DElncRNAs), and 7 differentially expressed miRNAs (DEmiRNAs), among which 37 were associated with prognosis and 11 were identified as diagnostic marker. The immune infiltration analysis suggested that components in the ceRNA may be related to changes in tumor immune microenvironment and development of LUAD.
Conclusion: This comprehensive analysis of the regulatory RNA network in LUAD has identified a list of RNA markers with implications for clinical use, RNAs in our constructed regulatory network are potential prognostic and diagnostic markers in LUAD.
Research on the urban water resources carrying capacity by using system dynamics simulation
Authors: Chen Xing , Xu Qin , Cai Jing 
Published: March 2023

Abstract
The relationship between water resources and social economy has become a restricting factor for sustainable development of cities around the world. Linhai City in eastern China has the fastest economic growing and population boom. The system dynamics model of water resources carrying capacity was established to analyze the interaction between society, economy and water resources of Linhai city. Six different modes of water resources utilization were designed. Taking total population, gross domestic product, industrial output value, tertiary industry output value, water consumption, water supply and sewage discharge as the measurement indexes, the research predicted the development status of water resources carrying capacity of Linhai City from 2015 to 2030 under different development modes. Through the simulation results, it is found that the water-saving measures can reduce the gap between water supply and demand only in the short term. In the long run, the adjustment of industrial structure can improve the water resources carrying capacity and simultaneously promote the economy. In addition, increase the water income sources as well as strengthen sewage treatment are also necessary to balance the water supply and demand.
Future projections of crop water and irrigation water requirements using a bias-corrected regional climate model coupled with CROPWAT
Authors: Agrawal Abhishek , Srivastava Prashant Kumar , Tripathi Vinod Kumar , Maurya Swati , Sharma Reema , D. J. Shrinivasa 
Published: March 2023

Abstract
The study is conducted to examine the climate change impact on rice Crop Water Requirement (CWR) and Net Irrigation Requirement (NIR) using the NASA Earth Exchange Global Daily Downscaled Projection (NEX-GDDP) coupled with the CROPWAT 8.0 model. The maximum temperature (Tmax), minimum temperature (Tmin), and rainfall projections for the baseline (years 1981–2015) and future (years 2030 and 2040) under Representative Concentration Pathway (RCP) 4.5 were derived from NEX-GDDP. To reduce the bias, linear scaling (LS) and the modified difference approach (MDA) were employed. Results show that LS performed better than the MDA along with improved statistical measures such as mean (μ), standard deviation (σ), and percent bias (Pbias), in the case of Tmax and Tmin (μ = 31.14 and 19.63 °C, σ = 5.75 and 6.78 °C, Pbias = 1.43 and 0.33%), followed by rainfall (μ = 2.67 mm, σ = 4.94 mm, and Pbias = 2.4%). The future climatic projections showed an increasing trend in both Tmax and Tmin, which are expected to increase by 1.7 °C by 2040. This would cause an increased range of 1.2 and 2% in 2030 and 2040, respectively. Due to a wide variation in effective rainfall (Peff), NIR could increase by 4 and 9% in 2030 and 2040, respectively. The above results may help formulate adaptation measures to alleviate the impacts of climate change on rice production.
Creatividad e ideales antropológicos: el ser humano ubicuo entre la homogeneización y la diversidad
Authors: Polo-Flórez Viviana 
Published: March 2023

El despliegue de la transformación puede ser visto como el desarrollo, que da poderío y que aviva la creatividad[1]. Esta, como esa capacidad que define a la especie humana, sugiere articulaciones desde la conformación del sujeto en relación con el tiempo y su contexto, evidenciada en la creación y la destrucción como variables permanentes de su existencia. Este escrito propone una mirada a la creatividad como dispositivo abierto, que es susceptible de clasificarse socialmente y desde la formación de tipo positivista entre lo que se considera bueno y lo que no. De este modo, pone de manifiesto cómo las capacidades y aspiraciones del ser humano han estado mediadas por la necesidad de cambiar de modo permanente todo lo que lo rodea, sin medir necesariamente sus consecuencias.
[1] En sus obras El pensamiento creativo (1995) y Pensamiento práctico (1992), Edward de Bono valida la creatividad como algo inherente a los seres humanos, cuyo óptimo desarrollo se da a partir de la eficiencia de los procesos y su finalidad. La inocencia, el desconocimiento, la curiosidad, la motivación son elementos que conforman la vocación creativa que caracteriza al ser humano.
Pemetaan Penelitian Seputar Akad Musyarakah pada Lembaga Keuangan Syariah: Studi Bibliometrik VOSviewer dan Literature Review
Authors: Budianto Eka Wahyu Hestya 
Published: March 2023

<p><em>This study aims to determine the map of research developments regarding Musyarakah contracts at Islamic Financial Institutions with a VOSviewer bibliometric study and a literature review study. The research was carried out for a period of 17 years from 2005 to 2021 by searching through the Garuda website (Garba Reference Digital) for the key to Musyarakah. And obtained 310 research articles. The search results were then analyzed descriptively</em><em> and</em><em> inputted to find out the visualization of the mapping of the development of topics and research subjects around the Musyarakah contract. The results of the study indicate that the number of publications regarding Musyarakah contracts has increased significantly every year, </em><em>and </em><em>based on the results of mapping visualization using VOSviewer, research on Musyarakah contracts is divided into 5 clusters. Meanwhile, based on the results of the literature review, there are 8 main themes and 124 research topics regarding Musyarakah contracts at Islamic Financial Institutions.</em></p><p> </p><p>Penelitian ini bertujuan untuk mengetahui peta perkembangan penelitian seputar akad Musyarakah pada Lembaga Keuangan Syariah dengan studi bibliometrik VOSviewer dan kajian <em>literature review</em>. Penelitian dilakukan selama kurun waktu 17 tahun dari tahun 2005 hingga 2021 dengan cara melakukan penelusuran melalui website Garuda (Garba Rujukan Digital) berkata kunci Musyarakah. Dan didapatkan 310 artikel penelitian. Artikel hasil penelusuran tersebut kemudian dianalisis secara deskriptif, diinput dan dianalisis untuk mengetahui visualisasi pemetaan perkembangan topik dan subjek penelitian seputar akad Musyarakah. Hasil penelitian menunjukkan bahwa jumlah publikasi seputar akad Musyarakah mengalami peningkatan secara signifikan setiap tahunnya, dan berdasarkan hasil visualisasi pemetaan menggunakan VOSviewer, penelitian seputar akad Musyarakah terbagi menjadi 5 kluster. Sedangkan berdasarkan hasil kajian <em>literature review</em>, terdapat 8 tema utama dan 124 topik penelitian seputar akad Musyarakah pada Lembaga Keuangan Syariah.</p>
Prevalence of Cytomegalovirus infection among pregnant women with cord blood examination
Authors: Fareed Yalda Karam , Abdalla Goreal Amer 
Published: March 2023

Objective: This study aimed at determining the prevalence of CMV infection among pregnant women at the end of pregnancy and CMV transmission to their newborns.
Methods: This is cross sectional study, 213 pregnant women at delivery and their newborn babies from the Obstetrics and Gynecology Hospital in Duhok /Iraq were enrolled. A questionnaire was prepared to be answered by participants, including age, place of residence, educational level, and obstetric history as number of births, any bad obstetric history such as abortion, still birth, intrauterine growth retardation, congenital anomalies after birth.3-5 ml of blood was drawn from each woman and examined by ELISA kit to check for the presence of Anti CMV IgM, IgG, then IgG avidity test for those with positive (IgG and IgM). Samples of cord blood were collected from newborns after birth and checked for the presence of CMV IgM by ELISA and CMV –DNA by conventional PCR using specific primers to diagnose congenital infection and determine the rate of viral transmission from infected women.
Results: Serological examinations showed that 212 (99.5%) participants were CMV-IgG positive, 15 (7%) were positive for anti-CMV IgM and IgG antibodies, IgG avidity test for 15 women were of high avidity (>89%) which indicated non primary infections. Cord blood of newborns of those 15 women with positive IgG and IgM tested negative for Anti CMV IgM by ELISA and no CMV-DNA was detected by PCR, which revealed no transmission from those pregnant to their newborns.
Conclusion: This study demonstrated high prevalence of CMV among examined pregnant women in Duhok city which makes them prone to non-primary infection. IgG avidity test is of high efficacy to interpret the detection of IgG and IgM together in pregnant women. Cord blood examination for the existence of CMV-IgM and CMV-DNA after delivery could exclude congenital infection.