bluuebunny/crossref_metadata_2025_split huggingface dataset:
GEFSv12 High- and Low-Skill Day-10 Tornado Forecasts
Authors: Miller Douglas E. , Gensini Vittorio A. 
Published: May 2023

Abstract
On average, modern numerical weather prediction forecasts for daily tornado frequency exhibit no skill beyond day 10. However, in this extended-range lead window, there are particular model cycles that have exceptionally high forecast skill for tornadoes because of their ability to correctly simulate the future synoptic pattern. Here, model initial conditions that produced a more skillful forecast for tornadoes over the United States were exploited while also highlighting potential causes for low-skill cycles within the Global Ensemble Forecasting System, version 12 (GEFSv12). There were 88 high-skill and 91 low-skill forecasts in which the verifying day-10 synoptic pattern for tornado conditions revealed a western U.S. thermal trough and an eastern U.S. thermal ridge, a favorable configuration for tornadic storm occurrence. Initial conditions for high skill forecasts tended to exhibit warmer sea surface temperatures throughout the tropical Pacific Ocean and Gulf of Mexico, an active Madden–Julian oscillation, and significant modulation of Earth-relative atmospheric angular momentum. Low-skill forecasts were often initialized during La Niña and negative Pacific decadal oscillation conditions. Significant atmospheric blocking over eastern Russia—in which the GEFSv12 overforecast the duration and characteristics of the downstream flow—was a common physical process associated with low-skill forecasts. This work helps to increase our understanding of the common causes of high- or low-skill extended-range tornado forecasts and could serve as a helpful tool for operational forecasters.

Significance Statement
This research provides a framework for the anticipation of a more (or less) skillful 10-day tornado forecast in an operational numerical weather prediction system. High-skill forecasts were associated with substantial tropical convection and warm sea surface temperature throughout the Pacific Ocean and Gulf of Mexico, whereas the underlying cause of low-skill forecasts were typically associated with a blocking anticyclone over eastern Russia. These findings are important because they permit increased or decreased confidence in a long-range forecast of tornado occurrence based on a dynamical prediction system.
Nationwide trends in the prevalence and incidence of depressive disorders and their correlates among adults with disabilities in Korea from 2006 to 2017
Authors: Lee Hwa-Young , Kim So Young , Yeob Kyoung Eun , Kim Yeon Yong , Park Jong-Hyock 
Published: May 2023

Background: Evidence suggests that people with disabilities are more likely to suffer from depression. Previous studies have focused on depressive disorders in specific disability types or age groups using small-scale cross-sectional samples. We investigated longitudinal trends in the prevalence and incidence of depressive disorders according to disability types and severity levels in the entire Korean adult population. Methods: The age-standardised prevalence and incidence of depressive disorders were investigated using National Health Insurance claims data from 2006 to 2017. The odds of depressive disorders by type and severity were examined using logistic regression after adjusting for sociodemographic characteristics and comorbidities based on merged 2006 to 2017 data. Results: Both the incidence and prevalence of depressive disorders were higher among the disabled than the non-disabled, with the prevalence gap being larger than the incidence gap. In regression analyses, adjusting for sociodemographic characteristics and comorbidities considerably reduced the odds ratios, particularly for incidence. The severity of disabilities was inversely associated with the incidence of depressive disorders. Brain injury and disabilities in major internal organs were associated with lower odds of developing depressive disorders than in non-disabled individuals. Conclusions: A significant proportion of depressive disorders in disabled individuals are caused by financial hardships or comorbidities rather than disabilities themselves. We must pay special attention to those who cannot access healthcare services due to severe disabilities and those whose depressive disorders are misdiagnosed as intellectual disabilities. More research is required to elucidate the causal mechanisms underlying depressive disorders in people with various types and severities of disabilities.
Euro-Burn I: Assessment of burnout syndrome in health workers in a mediterranean country during the SARS-CoV-2 pandemic
Authors: María Diaz Vizcaya Rosa , José Rodríguez Rivas María , Mariño Méndez Helia , Teresa Alvés Pérez María , López Castro José 
Published: May 2023

Background: Burnout syndrome (BS) has a negative impact among health professionals. Aims: Our research objective is to quantify the level of burnout in health workers of the Spanish National Health System during the COVID-19 pandemic using and comparing two independent measurement instruments. Methods: Cross-sectional, descriptive and multicenter study conducted through an anonymous online survey among health workers of the National Health System, measuring the level of burnout using the Maslach Burnout Inventory (MBI) and the Copenhagen Burnout Inventory (CBI). Results: A total of 448 questionnaires were analyzed, the mean age of the participants was 43.53 years (range: 20–64), 365 (81.5%) women. 161 (35.9%) participants presented BS measured with the MBI and 304 (67.9%) measured with the CBI. Regarding work contract, those who had greater job stability presented a higher degree of cynicism with respect to the eventual ones ( p = .010), the eventual ones presenting higher mean scores in professional efficacy ( p = .034). Urban workers had higher scores of exhaustion ( p < .001) and cynicism ( p < .001) than those living in rural areas. When comparing both tests, a high predictive value for exhaustion and cynicism was found to measure BS through the CBI (AUC = 0.92 and 0.84, respectively) and a low AUC with respect to the predictive value for efficacy (AUC = 0, 59). Conclusions: The results obtained show a high level of BS among the health workers who participated in our study. Both tests have an excellent correlation in the degree of exhaustion and cynicism, but not in efficacy. The BS measurement must be performed with at least two validated instruments to increase its reliability.
Determination of mechanical properties of nanocomposites reinforced with spherical silica nanoparticles using experiments, micromechanical model and finite elements method
Authors: Astaraki Sajjad , Zamani Ehsan , Golestanian Hossein , Mohamadipoor Reza 
Published: May 2023

In this research, experimental, numerical, and micromechanical methods are used to determine the effects of silica nanoparticle content on the elastic modulus of polymer matrix nanocomposites in tension and compression. The direct mixing method was used to prepare experimental samples containing 0.1, 0.25, and 0.5 volume fractions of silica nanoparticles. The elastic modulus of the nanocomposites is evaluated by the Einstein, Guth, Mori-Tanaka, Halpin-Tsai, Kerner, and Ji et al. micromechanical models. In addition, the elastic modulus of the nanocomposites is evaluated using the RVE method in ABAQUS software. The effects of volume fraction and diameter of silica nanoparticles, thickness, and adhesion exponent of the interphase on the elastic modulus of polymeric nanocomposite are extensively examined. Stiffer elastic modulus behavior is found in the presence of interphase region. The results indicate that the elastic modulus of nanocomposites reinforced with spherical silica nanoparticles is improved with increasing nanoparticle volume fraction, decreasing the nanoparticle diameter, increasing the interphase thickness, and decreasing the interphase adhesion exponent. The validity of the results of numerical and micromechanical models has been checked with experimental results. It can be seen that the results obtained from the experiments with 1 hour of ultrasonic waves in the tensile samples with volume fractions of 0.1, 0.25, and 0.5, compared to the pure sample, have increased by 5.4, 10.3, and 9.7 percent, respectively. Similarly, for compression samples with the same volume fractions, the results have increased by 7, 13, and 11 percent, respectively.
Effect of different modes of administration of dexmedetomidine on the quality of recovery in ambulatory thyroidectomy: a randomized, controlled trial
Authors: Gao Pei , Chen Wen , Rao Jin , Chen Chen , Lu Yao , Li Yuan-Hai 
Published: May 2023

Objective To compare the effects of two different administration methods of dexmedetomidine (DEX) used as an adjuvant to ropivacaine in ultrasound-guided bilateral intermediate cervical plexus block (CPB) in terms of efficacy and the duration of postoperative analgesia in patients undergoing ambulatory thyroidectomy. Methods This double-blind, randomized study enrolled patients who underwent thyroidectomy with ultrasound-guided bilateral intermediate CPB. Patients were randomized to receive either perineural administration of dexmedetomidine (group DP) or intravenous pumping of dexmedetomidine (group DI). The 40-item Quality of Recovery (QoR-40) questionnaire was used to assess the primary endpoint, which was the global QoR-40 score 24 h after the operation. Results Sixty patients were randomized equally into the two groups. The total QoR-40 score 24 h postoperatively was significantly higher in group DP than group DI (160.6 ± 9.1 versus 152.8 ± 7.9, respectively). Dimensions of physical comfort and pain scores were significantly higher in group DP than group DI. The visual analogue scale pain score scores were significantly lower in group DP than group DI at 12 and 24 h postoperatively. Conclusions DEX as an adjuvant to ropivacaine in ultrasound-guided intermediate CPB can improve the QoR-40 score and prolong postoperative analgesia. Trial registration number: ChiCTR2000031264 at www.chictr.org.cn on 26 March 2020.
Anterior Center-Edge Angle Is Less Reliable Than Anterior Wall Index to Predict Anterior Coverage of the Femoral Head
Authors: Slullitel Pablo A. , Holc Fernando , Buljubasich Martin , Latorre Marcos , Comba Fernando , Zanotti Gerardo , Marquesini Mauricio , Grammatopoulos George , Buttaro Martin A. 
Published: May 2023

Background: No consensus is available regarding which radiographic measurement most accurately correlates with anterior coverage of the femoral head. Purpose: (1) To determine the correlation between 2 measurements of anterior wall coverage: total anterior coverage (TAC) calculated from radiographs and equatorial anterior acetabular sector angle (eAASA) calculated from computed tomography (CT) scans; (2) to define the correlation between anterior center-edge angle (ACEA) and anterior wall index (AWI) with TAC and eAASA; and (3) to investigate what other radiographic metrics may help predict anterior coverage. Study Design: Cohort study (Diagnosis); Level of evidence, 3. Methods: The authors retrospectively reviewed 77 hips (48 patients) for which radiographs and CT scans were obtained for reasons other than hip-related pain. Mean age of the population was 62 ± 22 years; 48 (62%) hips were from female patients. Two observers measured lateral center-edge angle (LCEA), AWI, Tönnis angle, ACEA, CT-based pelvic tilt, and CT-based acetabular version, with all Bland-Altman plots within 95% agreement. Correlation between intermethod measurements was estimated with a Pearson coefficient. Linear regression was used to test the ability of baseline radiographic measurements to predict both TAC and eAASA. Results: Pearson coefficients were r = 0.164 (ACEA vs TAC; P = .155), r = 0.170 (ACEA vs eAASA; P = .140), r = 0.58 (AWI vs TAC; P = .0001), and r = 0.693 (AWI vs eAASA; P < .0001). Multiple linear regression model 1 showed that AWI (β = 17.8; 95% CI, 5.7 to 29.9; P = .004), CT acetabular version (β = −0.45; 95% CI, −0.71 to −0.22; P = .001), and LCEA (β = 0.33; 95% CI, 0.19 to 0.47; P = .001) were useful to predict TAC. Multiple linear regression model 2 revealed that AWI (β = 25; 95% CI, 15.67 to 34.4; P = .001), CT acetabular version (β = −0.48; 95% CI, −0.67 to −0.29; P = .001), CT pelvic tilt (β = 0.26; 95% CI, 0.12 to 0.4; P = .001), and LCEA (β = 0.21; 95% CI, 0.1 to 0.3; P = .001) accurately predicted eAASA. Model-based estimates and 95% CIs using 2000 bootstrap samples from the original data were 6.16 to 28.6 for AWI in model 1 and 15.1 to 34.26 for AWI in model 2. Conclusion: There was a moderate to strong correlation between AWI and both TAC and eAASA, whereas ACEA correlated weakly with the former measurements, thus not being useful to quantify anterior acetabular coverage. Other variables such as LCEA, acetabular version, and pelvic tilt may also help predict anterior coverage in asymptomatic hips.
Cryopreserved Adipose-Derived Stem Cell Sheets: An Off-the-Shelf Scaffold for Augmenting Tendon-to-Bone Healing in a Rabbit Model of Chronic Rotator Cuff Tear
Authors: Song Wei , Zhang Dongliang , Wu Di , Zhong Lin , Zhu Qi , Bai Zhenlong , Yu Weilin , Wang Chongyang , He Yaohua 
Published: May 2023

Background: Adipose-derived stem cell (ADSC) sheets have been shown to promote tendon-to-bone healing. However, conventional laboratory preparation methods for ADSC sheets are time-consuming and risky, which precludes their diverse clinical applications. Purpose: To explore the utility of off-the-shelf cryopreserved ADSC sheets (c-ADSC sheets) for rotator cuff tendon-to-bone healing. Study Design: Controlled laboratory study. Methods: The ADSC sheets were cryopreserved and thawed for live/dead double staining, TdT-mediated dUTP Nick-End Labeling (TUNEL) staining, scanning electron microscopy observation, and biomechanical testing. Clone formation, proliferative capacity, and multilineage differentiation of ADSCs within the c-ADSC sheets were assayed to explore the effect of cryopreservation on stem cell properties. A total of 67 rabbits were randomly divided into 4 groups: normal group (without supraspinatus tendon tears; n = 7), control group (repair alone; n = 20), fresh ADSC (f-ADSC) sheet group (repair; n = 20), and c-ADSC sheet group (repair; n = 20). Rabbit bilateral supraspinatus tendon tears were induced to establish a chronic rotator cuff tear model. Gross observation, micro–computed tomography analysis, histological or immunohistochemical tests, and biomechanical tests were conducted at 6 and 12 weeks after repair. Results: No significant impairment was seen in the cell viability, morphology, and mechanical properties of c-ADSC sheets when compared with f-ADSC sheets. The stem cell properties of ADSC sheets also were preserved by cryopreservation. At 6 and 12 weeks after the repair, the f-ADSC and c-ADSC sheet groups showed superior bone regeneration, higher histological scores, larger fibrocartilage areas, more mature collagen, and better biomechanical results compared with the control group. No obvious difference was seen between the f-ADSC and c-ADSC sheet groups in terms of bone regeneration, histological score, fibrocartilage formation, and biomechanical tests. Conclusion: c-ADSC sheets, an off-the-shelf scaffold with a high potential for clinical translational application, can effectively promote rotator cuff tendon-to-bone healing. Clinical Relevance: Programmed cryopreservation of ADSC sheets is an efficient off-the-shelf scaffold for rotator cuff tendon-to-bone healing.
Genealogy of Finance: Long-term History and Alternatives
Authors: Davis Ann E. 
Published: May 2023

In periods of history with rapid social and economic change, it is useful to examine the long-term history of particular arrangements. Money is one of these institutions that seems eternal and unchanging, but that has changed dramatically over time. For example, money was typically conceived as coins made of precious metal and stamped with the image of the ruler. As long-distance trade expanded in the early modern period, money was represented by paper, most often letters of exchange among merchants who trusted one another because of common membership in a community. The emergence of the fiscal/military state enabled populations to have some role in the issue and uses of money, such as the Italian city-states of Republican form, like Florence and Venice. After the “Glorious Revolution” in 1688, the Bank of England (BOE) innovated with merchant monopoly corporations engaging in state-supported long-distance trade, the stock of which backed public debt. The political controversies surrounding the formation of the BOE reveal some of the alternative possibilities, a merchant-oriented bank, supported by the Whigs, or a land bank supported by the Tories. After the industrial revolution, the use of credit for real investment aided the accumulation of surplus, by the productivity treadmill. After the Great Depression, the extension of finance into the lives of the citizens proceeded, with debt financing for housing, education, and retirement, encompassing the entire life cycle. The dominance of the United States after World War II enabled that country to sustain a hegemonic currency, based on the expansion of trade and supply chains to Emerging Market Countries. Along with the tech bubble in the second decade of the twenty-first century, the crypto bubble expanded hopes for an alternative form of money. Such a long-term history can be informed by analysis of the role of money as a symbol, mobilized by meanings enacted in human institutions. Such a view can provide a method of interpreting the long term evolution of money, restoring the political dimension and human agency to the abstract impersonal mechanical notion of the market. Such a perspective can better inform consideration of alternative institutions to accommodate challenges like geopolitical competition, war, and climate change. JEL Classification: B51, B52, G20, N20, P48
Ten-Year Trends in Lithium Prescribing in Alberta, Canada
Authors: Shafiq Samreen , Ronksley Paul Everett , Scory Tayler Dawn , Elliott Meghan Jessica , Bulloch Andrew Gabriel McKay , Patten Scott Burton 
Published: May 2023

Aims Despite lithium's clinical efficacy, it is commonly thought that its use is declining. The objective of this study is to describe the new and prevalent lithium users as well as rates of discontinuation of lithium use over a 10-year period. Methods This study used provincial administrative health data from Alberta, Canada between January 1, 2009 and December 31, 2018. Lithium prescriptions were identified within the Pharmaceutical Information Network database. Total and subgroup specific frequencies of new and prevalent lithium use were determined over the 10-year study period. Lithium discontinuation was also estimated through survival analysis. Results Between the calendar years of 2009 and 2018, 580,873 lithium prescriptions were dispensed in Alberta to 14,008 patients. The total number of new and prevalent lithium users appears to be decreasing over the 10-year timeframe, although the decline may have stopped or reversed in the latter years of the study period. Prevalent use of lithium was lowest among individuals between the ages of 18–24 years while the highest number of prevalent users were in the 50–64 age group, particularly among females. New lithium use was lowest amongst those 65 years and older. More than 60% (8,636) of patients prescribed lithium, discontinued use during the study timeframe. Lithium users between ages of 18–24 years were at the highest risk of discontinuations. Conclusions Rather than a general decline in prescribing, trends in lithium use are dependent on age and sex. Further, the period soon after lithium initiation appears to be a key time period in which many lithium trials are abandoned. Detailed studies using primary data collection are needed to confirm and further explore these findings. These population-based results not only confirm a decline in lithium use, but also suggest that this may have stopped or even reversed. Population-based data on discontinuation pinpoint the period soon after initiation as the time when trials are most often discontinued.
Perioperative Management of Extended-Release Buprenorphine: A Narrative Review and Case Series
Authors: Hickey Thomas R. , Meeks Thomas , Oxentine Heather , Park Dong Chan , Abelleira Audrey , Edens Ellen , Gordon Adam J. , Acampora Gregory 
Published: May 2023

Background: Perioperative management of formulations of buprenorphine used for the treatment of opioid use disorder and/or pain are common clinical challenges. Care strategies are increasingly recommending continuation of buprenorphine while administering multimodal analgesia including full agonist opioids. While this “simultaneous strategy” is relatively simple for the shorter-acting sublingual buprenorphine formulation, best practices are needed for the increasingly prescribed extended-release buprenorphine (ER-buprenorphine). To our knowledge there are no prospective data to guide perioperative management of patients on ER-buprenorphine. Herein we provide a narrative review, report on the perioperative experiences of a series of patients maintained on ER-buprenorphine, and propose recommendations for perioperative ER-buprenorphine management based on best evidence, clinical experience, and our judgments. Cases: Here we present clinical data describing the perioperative experiences of patients maintained on extended-release buprenorphine who recently underwent a variety of surgeries ranging from outpatient inguinal hernia repair to multiple inpatient surgeries for source control in sepsis, at different medical centers throughout the United States. These patients were identified via an email solicitation to substance use disorder treatment providers throughout a nationwide healthcare system, requesting cases of patients maintained on extended-release buprenorphine who had recently undergone surgery. We report here on all of the cases received. Discussion: Extrapolating from these and recently published case reports, we describe an approach to perioperative management of extended-release buprenorphine.