bluuebunny/crossref_metadata_2025_split huggingface dataset:
Projections of winter polynyas and their biophysical impacts in the Ross Sea Antarctica
Authors: DuVivier Alice K. , Molina Maria J. , Deppenmeier Anna-Lena , Holland Marika M. , Landrum Laura , Krumhardt Kristen , Jenouvrier Stephanie 
Published: September 2023

AbstractThis study investigates winter polynyas in the southern Ross Sea, Antarctica where several polynyas are known to form. Coastal polynyas are areas of lower sea ice concentration and/or thickness along the coast that are otherwise surrounded by more extensive, thicker sea ice pack. Polynyas are also locations where organisms can exploit both the ice substrate and pelagic resources. Using a self organizing map algorithm, we identify polynya events in the Community Earth System Model Version 2 Large Ensemble (CESM2-LE). The neural network algorithm is able to identify polynya events without imposing an ice concentration or thickness threshold, as is often done when identifying polynyas. The CESM2-LE produces a wintertime polynya feature comparable in size and location to the Ross Sea polynya, and during polynya events there are large turbulent heat fluxes and export of sea ice from the Ross Sea. In the CESM2-LE polynya event frequency is projected to decrease sharply in the later twentyfirst century, leading to increasing sea ice concentrations and thicknesses in the region. The drivers of the polynya frequency decline are likely both large scale circulation changes and local atmosphere and ocean feedbacks. If declines in wintertime polynya frequency over the twentyfirst century do occur they may impact Antarctic Bottom Water formation and local net primary productivity. Thus, better understanding potential local and unexpected sea ice changes in the Ross Sea is important for both assessing climate system impacts and ecological impacts on the Ross Sea ecosystem, which is currently protected by an internationally recognized marine protected area.
Common pathogenesis of early and late preeclampsia: evidence from recurrences and review of the literature
Authors: Arbuzova Svitlana 
Published: September 2023

Abstract
Objective
To investigate whether there is an association between the gestational age at the onset of preeclampsia in recurrent cases and the gestational age at the onset of preeclampsia in previous pregnancies.

Methods
This retrospective nested case–control study was designed to investigate whether gestational age at diagnosis and at delivery in recurrent cases of preeclampsia correlates with gestational age at diagnosis and delivery in the previous cases of preeclampsia in the same individuals. The database of a Ukrainian research network was used to find patients with the diagnosis of preeclampsia between 2019 and 2021. The database was further queried to identify those with a history of preeclampsia in a previous pregnancy. The comparison was made using the Pearson correlation coefficient.

Results
One hundred and three patients who were diagnosed with preeclampsia were identified. Of those, 15 had recurrent preeclampsia, 2 of whom had preeclampsia in 2 previous pregnancies. There was no statistically significant correlation: based on gestational age at delivery R = − 0.28 (P = 0.30; 95% confidence interval (− 0.69 to 0.28) and based on gestational age at the time of diagnosis R = − 0.14 (P = 0.62; − 0.60 to 0.41).

Conclusion
Our data do not find an association between the gestational age of recurrent preeclampsia and preeclampsia diagnosed in a previous pregnancy. This supports the idea that there is single pathogenesis for preeclampsia regardless of the gestational age. It suggests that there are variations in the course of preeclampsia that may be determined by the capacity of the compensatory mechanisms.
Dystonia and Parkinsonism in COA7-related disorders: expanding the phenotypic spectrum
Authors: Higuchi Yujiro , Ando Masahiro , Kojima Fumikazu , Yuan Junhui , Hashiguchi Akihiro , Yoshimura Akiko , Hiramatsu Yu , Nozuma Satoshi , Fukumura Shinobu , Yahikozawa Hiroyuki , Abe Erika , Toyoshima Itaru , Sugawara Masashiro , Okamoto Yuji , Matsuura Eiji , Takashima Hiroshi 
Published: September 2023

Abstract
Background and objective
Biallelic mutations in the COA7 gene have been associated with spinocerebellar ataxia with axonal neuropathy type 3 (SCAN3), and a notable clinical diversity has been observed. We aim to identify the genetic and phenotypic spectrum of COA7-related disorders.

Methods
We conducted comprehensive genetic analyses on the COA7 gene within a large group of Japanese patients clinically diagnosed with inherited peripheral neuropathy or cerebellar ataxia.

Results
In addition to our original report, which involved four patients until 2018, we identified biallelic variants of the COA7 gene in another three unrelated patients, and the variants were c.17A > G (p.D6G), c.115C > T (p.R39W), and c.449G > A (p.C150Y; novel). Patient 1 presented with an infantile-onset generalized dystonia without cerebellar ataxia. Despite experiencing an initial transient positive response to levodopa and deep brain stimulation, he became bedridden by the age of 19. Patient 2 presented with cerebellar ataxia, neuropathy, as well as parkinsonism, and showed a slight improvement upon levodopa administration. Dopamine transporter SPECT showed decreased uptake in the bilateral putamen in both patients. Patient 3 exhibited severe muscle weakness, respiratory failure, and feeding difficulties. A haplotype analysis of the mutation hotspot in Japan, c.17A > G (p.D6G), uncovered a common haplotype block.

Conclusion
COA7-related disorders typically encompass a spectrum of conditions characterized by a variety of major (cerebellar ataxia and axonal polyneuropathy) and minor (leukoencephalopathy, dystonia, and parkinsonism) symptoms, but may also display a dystonia-predominant phenotype. We propose that COA7 should be considered as a new causative gene for infancy-onset generalized dystonia, and COA7 gene screening is recommended for patients with unexplained dysfunctions of the central and peripheral nervous systems.
Comparison of functional and morphologic changes between brolucizumab and faricimab in neovascular age-related macular degeneration
Authors: Maruyama-Inoue Maiko , Yanagi Yasuo , Inoue Tatsuya , Kadonosono Kazuaki 
Published: September 2023

Abstract
Purpose
This study aimed to compare functional and morphologic changes in the loading phase between patients with treatment-naïve macular neovascularization (MNV) due to neovascular age–related macular degeneration (nAMD) treated with either intravitreal brolucizumab (IVBr) or intravitreal faricimab (IVF) injections in a clinical setting.

Methods
We retrospectively studied 92 consecutive eyes of 90 patients with neovascular nAMD who were scheduled to receive IVBr (42 eyes of 41 patients) or IVF (50 eyes of 49 patients) injections between October 2021 and December 2022. All patients received three consecutive monthly injections of 6.0 mg/0.05 mL brolucizumab or 6.0 mg/0.05 mL faricimab. The best-corrected visual acuity (BCVA), central foveal thickness (CFT), and central choroidal thickness (CCT) at baseline and 1, 2, and 4 months after the initial treatment were measured and compared between the groups.

Results
Thirty-seven eyes in IVBr group and forty-seven eyes in IVF group who finished treatments in the loading phase were assessed at the follow-up examination. The BCVA, CFT, and CCT changed significantly after loading phase in both groups (P < 0.05 for both comparisons). The IVBr group had more rapid improvement of the BCVA (P = 0.037) at 1 month than the IVF group, but there was no difference at 4 months (P = 0.367). The CFT and CCT decreases tended to be greater in the IVBr group than in the IVF group throughout the follow-up period. Of the five eyes excluded from the IVBr group, one eye (2.4%) each had intraocular inflammation (IOI) and was a non-responder, and two eyes (4.8%) had retinal pigment epithelial tears after treatment. Of the three eyes excluded from the IVF group, two eyes (4.0%) did not respond to the treatment.

Conclusions
Both IVBr and IVF injections were well-tolerated and improved the VA in treatment-naïve patients with MNV due to nAMD after a loading phase, although IVBr caused a trend toward faster visual improvements in the BCVA. The IVBr group also had greater reductions of the CFT and CCT than the IVF group. However, the potential for adverse events and no response to treatment with each drug are considerations.
An asymptotic formula for the variance of the number of zeroes of a stationary Gaussian process
Authors: Assaf Eran , Buckley Jeremiah , Feldheim Naomi 
Published: September 2023

AbstractWe study the variance of the number of zeroes of a stationary Gaussian process on a long interval. We give a simple asymptotic description under mild mixing conditions. This allows us to characterise minimal and maximal growth. We show that a small (symmetrised) atom in the spectral measure at a special frequency does not affect the asymptotic growth of the variance, while an atom at any other frequency results in maximal growth.
Cross-cultural adaptation of the Skin Cancer Index into Brazilian Portuguese for patients with cervicofacial nonmelanoma skin cancer
Authors: Hora Evânia Curvelo , Lima Marcela Sampaio , Siqueira Hianga Fayssa Fernandes , Marques Adriane Dórea , de Abreu Costa Brito Érika , Lessa Arthur Leite , Lima Carlos Anselmo 
Published: September 2023

Abstract
Purpose
This study aimed to translate the Skin Cancer Index (SCI) into Portuguese, adapt it for Brazilian culture, and clinically validate it.

Methods
A five-stage cross-cultural adaptation model was followed, with subsequent clinical validation. Inter-rater agreement was assessed using the content validity index (CVI). The hypothesis of the non-inferiority of the CVI at 80% probability level was evaluated using an exact binomial test. We used Spearman’s rank-order and Pearson’s product–moment correlation analysis, internal consistency using McDonald’s ω and Cronbach’s α metric, and construct validity using confirmatory factor analysis. The factorial model was validated using the chi-squared test, root mean square error of approximation (RMSEA), comparative fit index (CFI), and standardized root mean square residual (SRMR).

Results
The first stage yielded two independent translations. After synthesis, back-translation, and review, the prefinal version was tested on 40 patients. Inter-rater agreement indices on content validity were significantly higher than 80% (p < 0.05). The SCI remained stable, and the Spearman’s rank-order (rs), Pearson product–moment (r), and intraclass correlation coefficients were > 0.9, indicating excellent reliability. The reliability of McDonald’s ω was considered ideal (> 0.8) in all subdimensions and scale. Cronbach’s α was considered ideal in the “Emotional” and “Social” subdimensions and scale. Construct validity was observed in all subdimensions and scale through the criteria (χ2) p value > 0.05, RMSEA < 0.08, CFI ≥ 0.9, and SRMR ≤ 0.08.

Conclusion
The cross-cultural adaptation of the SCI to Portuguese for Brazilian culture showed content validity and reliability, contributing to quality of life assessment in patients with NMSC.
The indication of fusion to the pelvis in neuromuscular scoliosis is based on the underlying disease rather than on pelvic obliquity
Authors: Geiger Florian , Eberl Johanna , Wirries André , Forth Andreas , Hammad Ahmed 
Published: September 2023

Abstract
Introduction
The decision to instrument to L5 or ilium, in NMS, is usually based on radiologic factors, including pelvic obliquity (PO) > 15°, apex of curvature < L3, and Cobb angle > 60°. Since scoliosis in these patients is caused by a neurologic disease, we based our decision to stop at L5 on the presence of spasticity or flaccidity.

Patients & Methods
The senior author did 109 primary fusions in NMS. Of those with DMD or SMA only 16% were instrumented to the ilium. The main factor for our decision was the correction potential of the truncal shift and PO in the supine traction radiographs and the absence of severe spasticity.

Results
The 57 patients with DMD/SMA had a mean preoperative curvature of 68°, PO of 17°, and truncal shift of 20°. 74% should have been instrumented to the pelvis, but only 16% were. Those instrumented shorter as the rule, were corrected from 74° to 26° and had a postoperative PO of 8°. There was no significant difference in postoperative correction and PO compared to those instrumented to L5 on standard protocol. Subsequent extension to the pelvis was needed in 1 CP patient. There were no significant changes after 2 years. Of the 20 patients instrumented to the pelvis 11 had cerebral palsy and a preop curvature of 89°, a PO of 21° and a truncal shift of 25°.

Discussion
The decision on instrumentation length should take flexibility and disease into consideration. If the trunk is centred over the pelvis, deterioration will not occur in absence of spasticity.
Can metacognitive accuracy be altered through prompting in biology text reading?
Authors: Elsner Stefanie , Großschedl Jörg 
Published: September 2023

AbstractMetacognitive accuracy is understood as the congruency of subjective evaluation and objectively measured learning performance. With reference to the cue utilisation framework and the embedded-processes model of working memory, we proposed that prompts impact attentional processes during learning. Through guided prompting, learners place their attention on specific information during the learning process. We assumed that the information will be taken into account when comprehension judgments are formed. Subsequently, metacognitive accuracy will be altered. Based on the results of this online study with pre-service biology teachers, we can neither confirm nor reject our main hypothesis and assume small effects of prompting on metacognitive accuracy if there are any. Learning performance and judgment of comprehension were not found to be impacted by the use of resource- and deficit-oriented prompting. Other measurements of self-evaluation (i.e. satisfaction with learning outcome and prediction about prolonged comprehension) were not influenced through prompting. The study provides merely tentative evidence for altered metacognitive accuracy and effects on information processing through prompting. Results are discussed in light of online learning settings in which the effectiveness of prompt implementation might have been restricted compared to a classroom environment. We provide recommendations for the use of prompts in learning settings with the aim to facilitate their effectiveness, so that both resource-oriented and deficit-oriented prompts can contribute to metacognitive skill development if they are applied appropriately.
The use of ultrasonography as an effective screening tool for chronic posterior cruciate ligament injuries
Authors: Kimura Mitsuhiro , Nakase Junsuke , Yoshimizu Rikuto , Kanayama Tomoyuki , Yanatori Yusuke , Tsuchiya Hiroyuki 
Published: September 2023

Abstract
Purpose
We aimed to explore the applicability and validity of ultrasonography for diagnosing chronic posterior cruciate ligament (PCL) injuries.

Methods
PCL thickness was measured at 2 cm proximal to the tibia insertion site. Using the same ultrasonography image, the angle tangent to the PCL from the tibia insertion site was also measured. These data were analyzed by plotting the receiver operating curve (ROC), and the sensitivity and specificity were calculated according to the optimal cut-off point. Ultrasonography data from the PCLinjured knee were compared with those from the contralateral uninjured knee of the same patient.

Results
Twelve men and six women, with a mean age of 28.8 ± 14.0 years, were included in this study. The mean time from injury to medical examination was 10.0 ± 6.7 months. The mean thickness of the PCL was 8.1 ± 1.9 mm on the affected side and 5.8 ± 1.2 mm on the uninjured side, with the affected side being significantly thicker. ROC analysis revealed that the optimal cut-off value for the thickness of chronic PCL injuries was 6.5 mm (sensitivity 83.3%, specificity 77.8%, area under the curve [AUC] = 0.87). The optimal cut-off value for the angle was 20° (sensitivity 88.9%, specificity 94.4%, AUC = 0.96).

Conclusion
Ultrasonography is useful as a screening tool for chronic PCL injuries. The optimal cut-off point was 6.5 mm for thickness and 20° for angle.

Level of evidence
IV.
Behavioral and demographic responses of the predatory rotifer Asplanchna sieboldii (Leydig, 1854) fed prey (Plationus patulus (Müller, 1786)) previously exposed to cadmium and microplastics
Authors: Hernández-Lucero José Antonio , Sarma S. S. S. , Nandini S. 
Published: September 2023

AbstractWe quantified the feeding behavior (encounter, attack, capture and ingestion) and demographic parameters (survival and reproduction) of the predatory rotifer Asplanchna sieboldii fed on the prey Plationus patulus previously exposed to microplastics (MPs), Cd or their combination. As compared to controls, capture and ingestion rates of P. patulus by A. sieboldii decreased by 71 and 61%, respectively, with prey previously exposed to mixed MPs and Cd treatment. Life table data showed that the predator died earlier in controls than when fed on prey exposed to both Cd and microplastics. Regardless of the prey treatment, the offspring production by A. sieboldii increased as the available prey numbers increased (from 1 to 4 ind. ml−1). Compared to controls, the fecundity rate of the predator decreased when contaminated prey was offered as food.
Patients’ and Therapists’ Experiences of Standardized Group Cognitive Behavioral Therapy: Needs for a Personalized Approach
Authors: Gryesten Jasmin Rejaye , Poulsen Stig , Moltu Christian , Biering Elisabeth Belmudez , Møller Kirsten , Arnfred Sidse Marie 
Published: September 2023

AbstractPersonalizing psychotherapy can be challenging within standardized group Cognitive Behavioral Therapy (CBT), in which sessions are structured according to a protocol and must accommodate the needs and preferences of multiple patients. In the current study, we aimed to examine patients’ and therapists’ experiences of standardized group CBT and identify their perceptions of different patient needs. Furthermore, we explored how these needs can inform possible content of add-on interventions for patients who are not improving as expected during group CBT.We conducted 21 individual in-depth interviews with patients with depression and their therapists about their experiences during group CBT with Routine Outcome Monitoring (ROM) and feedback. Interviews were analyzed by using a hermeneutic-phenomenological thematic analysis. Five themes, representing different patient needs, were identified: (1) Individual attention, (2) Psychological exploration, (3) A focus on the patient’s life outside of therapy, (4) Extended assessment, and (5) Agreement on therapeutic tasks.The study supports that “one size does not fit all” when it comes to psychotherapy. Patients have varying needs when they are not making progress in therapy, and these needs, when unmet, can negatively impact the overall experience of group CBT. By acknowledging the unique needs of each patient and providing additional individual sessions as necessary, we can move towards a more personalized approach that maximizes the benefits of group psychotherapy.
Overall evaluation of the replacement of fermented soybean to fish meal in juvenile white shrimp, Litopenaeus vannamei diet: growth, health status, and hepatopancreas histomorphology
Authors: Abd El-Naby Asmaa S. , Eid A. E , Gaafar Alkhateib Y. , Sharawy Zaki , Khattaby A. A , El-sharawy Mohamed S. , El Asely Amel M. 
Published: September 2023

AbstractThis study was conducted to determine the effect of replacing fishmeal (FM) with fermented soybean meal (FSBM) for 12 weeks on the growth performance, feed utilization, immunological parameters, antioxidant enzyme assays and lipid peroxidation, digestive enzymes, and histopathological analysis of juvenile Litopenaeus vannamei (L. vannamei). By substituting 0.0%, 20%, 30%, and 40% FSBM for fishmeal (w/w), four isonitrogenous diets were generated. A total of 300 juvenile L. vannamei (1.59 ± 0.01 g) were randomly allocated to the experimental fiber tanks at a rate of fifteen shrimp per tank, with three replicates for each treatment. Growth performance and feed utilization decline considerably (P < 0.05) with increasing amounts of FM replacement with FSBM in diets. In comparison to the juveniles fed the other experimental diets, the diet containing a moderate level of FM replacement (20% FSBM) considerably enhanced growth performance and feed consumption during the feeding trial. The 20% FSBM-fed group had the highest protein content. In contrast, raising FSBM levels significantly increased lipid content (P < 0.05) compared to the control. However, there were no statistically significant differences (P > 0.05) across FSBM treatments. Hemolymph plasma total protein (TP) concentration and lysozyme activity were substantially greater (P < 0.05) in 20% FSBM compared to 40% FSBM (P < 0.05). In addition, 20% FSBM exhibits a substantial (P < 0.05) increase in the activity of antioxidant enzymes (CAT SOD, GPX, and GR). In contrast, the control and 30% FSBM groups had considerably more lipid peroxidation markers (MDA) than the 20% and 40% FSBM groups. Hepatopancreas amylase activity was considerably elevated (P < 0.05) in the control group and with 40% FSBM. In addition, hepatopancreas and intestinal protease and lipase activity increased significantly by 20% FSBM. Considerably, more B cells were present in the 40% FSBM diet than in the control diet; however, they were significantly less prevalent in the 20% and 30% FSBM diets (P < 0.05).
FuseBot: mechanical search of rigid and deformable objects via multi-modal perception
Authors: Boroushaki Tara , Dodds Laura , Naeem Nazish , Adib Fadel 
Published: September 2023

AbstractMechanical search is a robotic problem where a robot needs to retrieve a target item that is partially or fully-occluded from its camera. State-of-the-art approaches for mechanical search either require an expensive search process to find the target item, or they require the item to be tagged with a radio frequency identification tag (e.g., RFID), making their approach beneficial only to tagged items in the environment. We present FuseBot, the first robotic system for RF-Visual mechanical search that enables efficient retrieval of both RF-tagged and untagged items in a pile. Rather than requiring all target items in a pile to be RF-tagged, FuseBot leverages the mere existence of an RF-tagged item in the pile to benefit both tagged and untagged items. Our design introduces two key innovations. The first is RF-Visual Mapping, a technique that identifies and locates RF-tagged items in a pile and uses this information to construct an RF-Visual occupancy distribution map. The second is RF-Visual Extraction, a policy formulated as an optimization problem that minimizes the number of actions required to extract the target object by accounting for the probabilistic occupancy distribution, the expected grasp quality, and the expected information gain from future actions. We built a real-time end-to-end prototype of our system on a UR5e robotic arm with in-hand vision and RF perception modules. We conducted over 200 real-world experimental trials to evaluate FuseBot and compare its performance to a state-of-the-art vision-based system named X-Ray (Danielczuk et al., in: 2020 IEEE/RSJ international conference on intelligent robots and systems (IROS), IEEE, 2020). Our experimental results demonstrate that FuseBot outperforms X-Ray’s efficiency by more than 40% in terms of the number of actions required for successful mechanical search. Furthermore, in comparison to X-Ray’s success rate of 84%, FuseBot achieves a success rate of 95% in retrieving untagged items, demonstrating for the first time that the benefits of RF perception extend beyond tagged objects in the mechanical search problem.