bluuebunny/crossref_metadata_2025_split huggingface dataset:
USO DE HORMÔNIOS ISOMOLECULARES NA HARMONIZAÇÃO OROFACIAL EM MULHERES NA MENOPAUSA
Authors: Souza Mário Silveira de , De Souza Daniela Martins , Bastos Bruno , De Souza Vítor Gueno , Rizzatti-Barbosa Célia Marisa 
Published: July 2023

O estudo teve como objetivo avaliar, por meio de ensaio clínico randomizado e duplo cego, os efeitos da utilização de creme de uso tópico contendo hormônios isomoleculares e/ou bioidênticos na estética facial e saúde orofacial de mulheres em menopausa. Metodologia. Mulheres em menopausa (n=50) foram divididas em 2 grupos: grupo tratado que recebeu aplicação tópica na face de creme contendo estriol (E3), estradiol (E2) e progesterona (P4), enquanto o grupo controle recebeu o creme placebo com a base/veículo, sem adição de hormônios, considerando doses diárias e follow up de 53 dias. Os resultados apontaram para aumento do nível de estrogênio (p=0,0110), aumento do fluxo salivar (p=0,0396) e melhora da estética facial, na qual foi observado melhoria de 60% no grupo tratado, quando avaliação de registros fotográficos pré e pós-tratamento foi feita por especialistas em Harmonização Orofacial. Evidências sinalizam para a relação entre a terapia de modulação hormonal tópica com a melhoria de aspectos relacionados à saliva, saúde oral e estética facial de mulheres em menopausa. Concluiu-se que o uso de creme facial com hormônios (E2, E3 e P4), usado diariamente durante o período de 53 dias, promoveu o aumento do fluxo salivar, melhoria da saúde oral, melhoria do contorno e rejuvenescimento facial de mulheres em menopausa.
UTILIZAÇÃO DOS FIOS ABSORVÍVEIS DE POLIDIOXANONA NO REJUVENESCIMENTO FACIAL
Authors: Serraglio André Izabela 
Published: July 2023

Objetivo: Avaliar os efeitos da utilização dos fios absorvíveis de polidioxanona (PDO) no rejuvenescimento facial. Revisão Bibliográfica: O rejuvenescimento facial é um procedimento estético bastante procurado, e uma das técnicas utilizadas é a utilização de fios absorvíveis de polidioxanona (PDO). Esses fios são inseridos na pele através de pequenas incisões e têm como objetivo proporcionar um efeito lifting, melhorando a flacidez e a textura da pele. Os fios absorvíveis de PDO são fabricados a partir de um material biocompatível e reabsorvível pelo organismo ao longo do tempo. Eles estimulam a produção de colágeno e elastina na pele, promovendo uma melhora na firmeza e na elasticidade. Durante o procedimento, os fios são inseridos na camada subcutânea da pele, criando uma estrutura de suporte que eleva e reposiciona os tecidos faciais. Os fios podem ser ancorados em pontos estratégicos para obter o efeito desejado, como lifting de sobrancelhas, redução de flacidez no pescoço, melhora do contorno facial e diminuição de rugas e sulcos. Conclusão: A técnica apresenta como uma das suas vantagens dos fios absorvíveis de PDO é a sua segurança e a baixa ocorrência de efeitos colaterais. Geralmente, o procedimento é minimamente invasivo e realizado em consultórios ou clínicas estéticas, com anestesia local. O tempo de recuperação é relativamente curto, e os resultados são naturais e duradouros, podendo ser observados imediatamente após o procedimento e melhorando progressivamente à medida que o colágeno é produzido.
The Moderating Role of Fund Size on the Relationship between Overconfidence and Portfolio Financial Performance of Mutual Funds in Kenya
Authors: Wafula Douglas Simiyu , Tibbs Charles Yugi , Benedict Ondiek Alala 
Published: July 2023

A decline in financial performance has recently been observed for a number of mutual funds in Kenya. Overall, differences in important metrics show inconsistent economic performance among Kenya's mutual funds year over year. It was critical to determine whether overconfidence bias would be to blame for the portfolio performance trend while evaluating this. The goal of this study was to ascertain the impact of overconfidence bias on mutual funds' performance in Kenya and to scrutinize the moderating effect of fund size on the relationship between overconfidence and mutual funds’ portfolio performance in Kenya. The study employed a causal research design. Study panel data were gathered. Secondary information was gathered from previously released financial statements of mutual funds during a period of eleven years, from 2011 to 2021. With the use of the data gathering tool, secondary data was gathered. Stata software version 15 was used to conduct the data analysis. A test for stationarity called the unit root test was conducted. Regression using panel data was utilized. Regression analysis with fixed and random effects was utilized. The following tests were run to determine the validity and reliability of the data: the Levin-Lin-Chu test, the Augmented Dickey-Fuller test, the Im-Pesaran and Shin tests, the Philips-Peron test, and the Hadri 2000 test. The Jarque-Bera test was used to gauge normality. In the panel analysis, the random effects model and the fixed effects model were separated using the Hausman test. The variables were distributed properly, as shown by the skewedness and kurtosis tests. There was no approaching multicollinearity among the variables, according to the pairwise correlation study. The findings showed that Overconfidence had a positive substantial influence on the financial performance of mutual funds in Kenya with a regression coefficient of 2.7295960. The study additionally found that fund size influences the financial performance of mutual funds in Kenya by negatively moderating the relationship between overconfidence and mutual funds’ financial performance in Kenya with a coefficient of -3.023683. Based on the results of the multiple regression analysis, it should be underlined when making financial investment decisions that overconfidence, with a regression coefficient of 2.7295960, had a favorable but significant impact on the financial performance of Kenyan mutual funds. The study, therefore, recommends that overconfidence should be emphasized during financial investment decision-making processes.
Globigerinoides rublobatus – a new species of Pleistocene planktonic foraminifera
Authors: Latas Marcin , Pearson Paul N. , Poole Christopher R. , Fabbrini Alessio , Wade Bridget S. 
Published: July 2023

Abstract. We describe Globigerinoides rublobatus n. sp., a new morphospecies of fossil
planktonic foraminifera, from the Pleistocene sediments (∼810 ka) of the Indian Ocean and Pacific Ocean. We use image analysis and morphometry
of 860 specimens from International Ocean Discovery Program Site U1483 in
the tropical Indian Ocean to document morphological variability in the new
morphospecies and related taxa, and we also report it from Pacific Ocean
Site U1486 for the first time. The new morphospecies combines
characteristics typical of Globigerinoides conglobatus (Brady, 1879) and Globigerinoides ruber (d'Orbigny, 1839), with which
it co-occurs, but is distinct from both. Morphometric data indicate that G. rublobatus n.
sp. is closer to G. conglobatus, potentially signalling an evolutionary affinity. We
find that Globigerinoides rublobatus n. sp. occurs as two variants, a pigmented (pink) form and a
non-pigmented (white) form. The non-pigmented forms are on average
∼50 % larger than the pigmented forms. This is so far only
the third instance of fossil planktonic foraminifera known to exhibit this
pink pigmentation. We regard the pink and white forms as variants of a
single morphospecies and suggest the pink form may represent a later
evolutionary adaptation.
ПРОБЛЕМЫ ЭФФЕКТИВНОСТИ УПРАВЛЕНИЯ ЗДРАВООХРАНЕНИЕМ РЕСПУБЛИКИ КАЗАХСТАН
Authors: Baraboshkin V. , Baigabulova K. , Kushebina G. , Burtebayeva A. , Барабошкин В.К. , Байгабулова К.К. , Кушебина Г.М. , Буртебаева A.А. 
Published: July 2023

The key factor that determines the relevance of the study of the author is the importance of continuing and developing the processes of modernization in the healthcare economy, provided for in the state program of development of healthcare of the Republic of Kazakhstan "Densaulyk", as well as the "Strategy-2050". Currently, a number of unresolved problems aimed at improving the quality of medical services, the efficiency of the health care system as a whole and at the level of medical organizations have been identified, which are reflected in this article. The article shows essential modifications affecting the provision of medical organizations with high-tech treatment and diagnostic equipment, as well as addressing issues related to their informatization through the introduction of medical information and analytical support systems aimed at automating the basic processes of medical activity. The experts argue that in order to obtain the greatest efficiency and productivity of medical organizations, it seems advisable to introduce process-oriented quality management systems in healthcare, which represent a synthesis of professional management and current information technologies. The objectives of the work are to study the fundamental issues of quality management in healthcare organizations and to examine the quality management system. On the results of the study the authors come to the relevant findings.
Главным фактором, определившим актуальность авторского исследования, выступает необходимость продолжения и развития процессов модернизации в экономике здравоохранения, предусмотренных в рамках государственной программы развития здравоохранения Республики Казахстан «Денсаулық», а также «Стратегии-2050». В настоящее время обозначился ряд нерешенных задач, которые были направлены на повышение качества медицинских услуг, эффективности функционирования системы здравоохранения как в целом, так и на уровне медицинских организаций, которые отражены в данной статье. В статье показаны значимые преобразования, влияющие на повышение обеспеченности медицинских организаций высокотехнологичным лечебно- диагностическим оборудованием, а также решение вопросов, связанных с их информатизацией посредством внедрения медицинских информационно- аналитических систем, направленных на автоматизацию основных процессов медицинской деятельности. Авторами обосновано, что целью достижения наибольшей результативности и эффективности функционирования медицинских организаций представляется целесообразным внедрить процессно-ориентированные системы управления качеством услуг в здравоохранении, представляющие собой синтез профессионального менеджмента и современных информационных технологий. Задачи исследования определены в изучении основных аспектов менеджмента качества в организациях здравоохранения и анализе системы менеджмента качества. На основе проведенного исследования авторами сделаны соответствующие выводы.
IMPROVING CRITICAL THINKINGABILITY THROUGH GUIDED DISCOVERY METHODS ASSISTED BY CABRI 3D SOFTWARE
Authors: Batubara Ismail Hanif , Sari Indah Purnama 
Published: July 2023

This research proves that the use of knowledge of software programs such as Cabri 3D improves college students' Critical Thinking competencies compared to those with the software program's help. This evidence is accomplished to reach the development of college students' numerical thinking capacities instructed to use guided disclosure gaining knowledge of strategies assisted with the aid of using Cabri 3D with the guided discovery gaining knowledge of approach without a Computer program. This lesson experimental research takes a look at a populace of 122 people. Randomly instructions are decided on from the to be had guides divided into pattern instructions. The first experimental magnificence changed into given remedy with the aid of using Guided Discovery gaining knowledge of Method assisted with the support of using an Cabri 3D software program, at the same time as some other degree changed into given remedy with the aid of using guided discovery gaining knowledge of approach without Cabri 3D software program. The tool used on this take a look at changed into a check. Then the check effects are examined through the use of the t-check with the assist of SPSS. The check standards are rejected H0 if the table of t is smaller than the t count. Effects confirmed rely on changed into 2,785 simultaneously as the t desk changed into 2,000. The college students taught with the aid of using the guided discovery gaining knowledge of approach assisted with using Cabri 3D (First experiment) are better than without software.
SKILLS BASED COMPETENCY AND COMPETITIVENESS OF ACCOUNTING PRACTITIONERS IN ASEAN EMERGING MARKET
Authors: Pane Sanusi Gazali , Siregar Saparuddin 
Published: July 2023

Competency frameworks are urgently needed by accounting practitioners within organizations to carry out their roles effectively. Moreover, in the context of economic integration and labor mobility between regional countries, the role of accounting practitioners becomes one of the eight professions affected by professional competition. The purpose of this research is to measure the level of competence of accounting practitioners using competency assessment methods that refer to technical and non-technical assessments through the collection of relevant evidence on accounting work. The results of this study showed that during the testing period of 2018-2020 as many as 83.01 failed to meet the level of competence. While 16.01 percent have competency standards in the qualification of accounting technicians and professional clusters. The implications of these findings illustrate that the difficulty of labor market accessibility in the domestic and regional arena will increase and the resulting competitiveness will be lower. Improvisation is controlled and relevant to, especially in the world of education by directing a paradigm-based curriculum competency framework. This concept is at least in line with the government's commitment to create superior human resources for Indonesia to grow and be more advanced.
Prophecies in The Holy Qur’an Attesting Its Divine Origin
Authors: Azzubaidi Marwan Saad 
Published: July 2023

A fundamental pillar in the Islamic faith is the belief that Allah is the only Being who knows how the unseen events and facts will exactly happen in the future. Therefore, it was reasonable to find prophecies in the Qur’an as evidence to prove that this book is the truth from God. The present article aimed to shed the light on the major prophecies mentioned in the Holy Qur’an testifying for its truthfulness as a religious book sent from God to his last and final messenger, Prophet Muhammad peace and blessings upon him (PBUH). Eight Qur’anic prophecies were categorized and discussed in this article. The first category comprised prophecies that came true during the Prophetic life span, which we referred to as “near-future happenings”. The second category included events that have come true after Prophet Muhammad PBUH has passed away which we termed “far-future happenings”. The third category included far-future news that was foretold to uncover an ancient event. The fourth category covers two undeniable consistent facts that become more evident as time passes. Appropriate understanding of these prophecies is essential for every Muslim to present and prove Islam to people as the religion of truth.

Keywords: Prophecy, Qur’an, proof, divine, origin.
Purple Urine Bag Syndrome in a Woman with Squamous Cell Cervical Cancer
Authors: Eubanks Rhea , Dupont Crystal , Fru Diane , Jackson Amanda , Herzog Thomas , Billingsley Caroline 
Published: July 2023

Purple urine bag syndrome is a rare phenomenon whose striking presentation can lead to earlier recognition and treatment of a potentially serious medical condition. This is a unique condition of long11 term indwelling catheter associated urinary tract infection with distinct, purple-colored urine caused by bacterial metabolites. This infrequent occurrence was seen in a patient with stage IIIb squamous cervical cancer who presented to the emergency department with symptoms of a urinary tract infection in setting of indwelling bilateral percutaneous nephrostomy tubes. The patient’s physical exam was notable for left costovertebral tenderness, purple urine in bilateral nephrostomy bags and urine culture significant for proteus mirabalis. The patient was treated with intravenous antibiotics and fluid resuscitation. She unfortunately left against medical advice shortly after being admitted. She re presented to an outside hospital with fevers and non-draining nephrostomy tubes notable to have purulent discharge at the nephrostomy sites. The scant urine through the nephrostomy tubes was also noted to have a purple hue. She was found to have another urinary tract infection with Enterobacter cloacae and subsequently treated with intravenous antibiotics. During this admission, she underwent bilateral nephrostograms notable for significant clogging of tubes and bilateral ureteral patency. After the study, she underwent removal of the long-term indwelling catheters and was able to continue voiding spontaneously. She was discharged in good condition on a ten-day course of oral antibiotics. The occurrence of purple urine is highly associated with urinary tract infections. This process is thought to be caused by a metabolism of dietary tryptophan by intestinal bacteria to indole that is then absorbed into the circulation and then converted to indoxyl sulfate by hepatic enzymes. This substrate returns to circulation and is excreted in the urine where in the presence of bacteria with sulfatase and phosphatase activity converts indoxyl sulfate to indigo and indirubin resulting in the characteristic purple hue of the urine. Catheter associated urinary tract infections require antibiotic treatment and timely removal of catheter when appropriate to prevent complications including pyelonephritis and sepsis.
Preface: 4th International Conference on Mechanical Engineering, Civil Engineering and Material Engineering (MECEME 2023)
Authors: Cissie Mirabelle , Cao Huilei 
Published: July 2023

It is with great pleasure to introduce the proceedings of the 2023 4th International Conference on Mechanical Engineering, Civil Engineering and Material Engineering (MECEME 2023). The conference was held during May 13-14, 2023 in Shenyang, China.
MECEME series provides a forum for accessing to the most up-to-date and authoritative knowledge from both industrial and academic worlds, sharing best practice in the fields of mechanical engineering, green manufacturing, architectural design, construction technology, civil engineering, and material engineering. This conference provides an opportunity to highlight recent developments and to identify emerging and future areas of growth in these exciting fields.
MECEME 2023 has the main purpose to bring researchers and scholars to share their knowledge and experiences. This conference provided delegates with a good opportunity to exchange new ideas, establish research and/or business contacts, and establish potential partnerships for global partnerships. We sincerely hope that this conference will help to increase knowledge in relevant scientific and academic fields.
Scientific Committee of MECEME 2023
Shenyang, China
Study on characteristics and community structure of high-speed rail network centered on Shanghai
Authors: Sun Jiayi 
Published: July 2023

The high-speed railway is a typical representative of China 's high-speed transportation infrastructure, with typical complex network characteristics. Based on the complex network theory, this paper conducts an empirical study on a Space-P network model for high-speed train originating from Shanghai. Then the network is divided into communities by louvain algorithm. The average distance of the network is 1.76, the modularity of community division is 0.3683, and the clustering coefficient is 0.6859, which is typical of small-world network. Due to Space-P model, the network is highly connected, resulting in a relatively low modularity. To a certain extent, the network reflects the developed high-speed rail level and wide direct range of Shanghai, and also reflects the convenience of China 's high-speed rail.
Effect of Glipizide on non-insulin-dependent diabetes mellitus
Authors: Yuan Jiarui 
Published: July 2023

Type 2 diabetes mellitus, sometimes referred to as non-insulin-dependent diabetes, (NIDDM). The patient was unable to secrete enough insulin, resulting in elevated blood glucose. Complications during a patient's diseases are common in type 2 diabetes patients. Common type 2 diabetes does not have an age or gender difference. Patients with type 2 diabetes or those under treatment are frequently fat and sedentary. Glipizide, a sulfonylurea medication, is prescribed to people with non-insulin-dependent diabetic mellitus. (type 2 diabetes). There are two common types, oral tablets and sustained-release tablets. The common type of oral tablets is fast-acting tablets. Absorption is rapid and the effect is rapid, because oral tablets have a significant effect and may cause short-term hypoglycemia. The body disintegrates the medication and release it. A contributing factor to type 2 diabetes is having high blood glucose levels, as the pancreas produces less insulin, resulting in a residual overall glucose in the blood. These disorders are often caused by genetics or overweight/physical inactivity . The blood glucose levels of patients with type 2 diabetes are greater than those of ordinary healthy individuals since the condition is a chronic metabolic disorder. Glipizide can be used as an insulin secretagogue to stimulate islet β cells to release insulin, thereby increasing plasma insulin concentration. It also serves as an auxiliary hand in diet and exercise. Different regions have different laws for the use of glipizide. Glipizide can be used in combination with other NIDDM drugs in the United States. It can only be used alone or not in the United Kingdom because of the high risk of aggravating hypoglycemia in patients. Patients who have any cardiovascular or renal disease or have a long history do not mind using these drugs. Such agents are likely to worsen the hypoglycemia associated with the disease. Among many drugs, glipizide is one of the most common sulfonylureas and has a moderate price.
Study on the technology of kumquat grapefruit sour beer
Authors: Hou Chengyue , Jiang Jialin , Bo Wenfei , Tang Simin , Qin Xiaoxu , Dong Xiaolei 
Published: July 2023

A kumquat-grapefruit acid beer was brewed with Australian barley malt, lactobacillu, D17 yeast, Qingdao hop flower, kumquat concentrated juice and grapefruit concentrated juice as raw materials by using special mash and fermentation process. The effects of acidification degree, the addition amount of kumquat and grapefruit juice concentrate and the addition time on beer flavor were studied in this paper. The results showed that when the pH was adjusted to 3.5 by acidification, the sour beer produced by adding 6% kumquat concentrated juice and 4% grapefruit concentrated juice before the CO2 pressure of the tank rised, the beer has white and exquisite foam with prominent fruit aroma, especially those of kumquat and grapefruit. The beer body was clear and transparent, with about 5% residual sugar. The sweet and sour taste of the beer was balanced. The beer contained unique nutrients of kumquat and grapefruit also, and was especially suitable to drink for brewers and ladies.