bluuebunny/crossref_metadata_2025_split huggingface dataset:
Method development and validation of lamivudine and stavudine in bulk and its tablet dosage form by reverse phase high performance liquid chromatography method
Authors: Siddanthapu Chilakamma  , B. Sravanasree  , T.K.V. Kesav Rao  
Published: September 2023

A rapid and precise reverse phase High Performance Liquid Chromatographic method has been developed for the validation of Stavudine and Lamivudine, in its pure form as well as in tablet dosage form. Chromatography was carried out on a Phenomenex Gemini C18 (4.6×250mm) 5µ column using a mixture of Methanol: TEA Buffer (65:35 v/v) as the mobile phase at a flow rate of 1.0ml/min, the detection was carried out at 230nm. The retention time of the Stavudine and Lamivudine was 2.121, 3.643 ±0.02min respectively. The method produce linear responses in the concentration range of 5-25µg/ml of Stavudine and 18.75-93.75µg/ml of Lamivudine. The method precision for the determination of assay was below 2.0%RSD. The method is useful in the quality control of bulk and pharmaceutical formulations.
Analisis Faktor-Faktor yang Mempengaruhi Minat Mahasiswa dalam Memilih Program Studi Pendidikan Ilmu Pengetahuan Sosial (IPS) Fakultas Keguruan dan Ilmu Pendidikan Universitas Pasir Pengaraian
Authors: Rayana Enggi , Rohmah Rina Ari , Hardianto  
Published: September 2023

Penelitian ini bertujuan untuk mengetahui faktor yang paling dominan mempengaruhi minat mahasiswa dalam memilih Program Studi Pendidikan Ilmu Pengetahuan Sosial (IPS) Fakultas Keguruan dan Ilmu Pendidikan Universitas Pasir Pengaraian. Populasi dalam penelitian ini adalah mahasiswa Program Studi Pendidikan Ilmu Pengetahuan Sosial (IPS) Fakultas Keguruan dan Ilmu Pendidikan Universitas Pasir Pengaraian. Jumlah sampel yang ditetapkan sebanyak 59 responden dengan menggunakan metode Simple Random Sampling. Hasil penelitian menunjukkan terdapat 1 faktor internal yang menjadi penyebab terbesar faktor yang mempengaruhi minat mahasiswa dalam memilih Program Studi Pendidikan Ilmu Pengetahuan Sosial (IPS) Fakultas Keguruan dan Ilmu Pendidikan Universitas Pasir Pengaraian yaitu faktor motivasi dengan nilai Eigenvalue sebesar 5,285 dan nilai varians sebesar 27,81%. Terdapat 1 faktor eksternal yang menjadi faktor yang mempengaruhi minat mahasiswa dalam memilih Program Studi Pendidikan Ilmu Pengetahuan Sosial (IPS) Fakultas Keguruan dan Ilmu Pendidikan Universitas Pasir Pengaraian yaitu faktor peluang kerja dengan nilai Eigenvalue sebesar 3,570 dan nilai varians sebesar 23,80%.
Perbandingan Perkembangan Prinsip Hukum Ekonomi Syariah di Indonesia, Malaysia, dan Brunei Darussalam
Authors: Zulkifli  
Published: September 2023

This study aims to examine the development of sharia economy law in three selected countries as seen from the progress of Islamic banking in the Southeast Asian Region. The objects of this study are Indonesia, Malaysia and Brunei Darussalam. The method used is descriptive analytical with normative juridical approach and literature review. The results showed differences in the development of sharia economic law in the three countries studied but not significantly. The practice of resolving sharia economic disputes in Indonesia by litigation can be resolved into 2 alternatives, namely by simple (MA Regulation Number 14 of 2016) and ordinary (MA Regulation Number 2 of 2015). While Islamic banking in Malaysia has sharia economic laws, namely the Islamic Banking Act (IBA) and the Bank and Financial Institutions Act (BAFIA). While in Brunei Darussalam refers to the principles of anti-usury, Ijarah, Musyarakah Musawwamah and certificates and other relevant sharia economic regulations that are manifested from various services and banking products.
Des centres et des marges. La trajectoire de Julie Doucet
Authors: Legendre Izabeau , Lefort-Favreau Julien 
Published: September 2023

Cet article propose d’analyser la trajectoire de Julie Doucet en tant que révélatrice des dynamiques et enjeux relatifs aux sphères de production culturelle dans lesquelles elle s’inscrit. Depuis ses débuts dans la bande dessinée « underground » montréalaise dans la deuxième moitié des années 1980 jusqu’à son prétendu « adieu » au média à la fin de la décennie suivante, Julie Doucet a parcouru quelques-uns des lieux les plus importants de la bande dessinée nord-américaine et européenne. De Montréal à Berlin, en passant par New York, Portland (Oregon) et Paris, suivre cette trajectoire équivaut à cartographier le renouveau de la bande dessinée au cours de la décennie 1990, des deux côtés de l’Atlantique. L’oeuvre de Doucet a été largement étudiée et est considérée comme emblématique de la bande dessinée des années 1990, car elle épouse quelques-unes des caractéristiques principales de l’époque : dimension autobiographique; travail sur le corps, la sexualité et l’abject; et un penchant féministe. À ces thématiques, nous proposons d’ajouter celle de l’éclatement du média qu’elle opère par des formes et techniques nouvelles. À cet effet, une attention particulière sera d’ailleurs accordée à la place qu’occupe la bande dessinée de Doucet dans un ensemble plus grand de pratiques, notamment la relation qu’elle entretient avec les marges de la production culturelle. La production de zines de Doucet - tant avant sa professionnalisation au tournant des années 1980 et 1990 qu’après son retrait au tournant 1990-2000 - en est le signe le plus évident. Il s’agit d’ailleurs d’une question qui travaillera notre article de manière souterraine : comment se négocie le rapport de la marge au centre pour une artiste comme Doucet, particulièrement au regard de l’intégration tardive de la bande dessinée au champ culturel? De ce point de vue, un opérateur central de travail de Doucet se révèle : le jeu avec le positionnement d’outsider. Cet opérateur est perceptible à la fois à la lecture interne des oeuvres (le choix des thèmes, de la langue, et l’exploration formelle au coeur de sa démarche), et dans les choix éditoriaux et stratégiques de l’autrice (le rapport à la bande dessinée sur la longue durée et le retour au zine, la mobilité, les commentaires de Doucet sur son parcours et son oeuvre). Cet article présente finalement, et pour la première fois, une bibliographie exhaustive des publications de Doucet, incluant toute sa production autoéditée, de la deuxième moitié des années 1980 à aujourd’hui.
De Jessie à Muriel, super-héroïnes tchèques face à la normalisation. Sur l’oeuvre transmédiatique du dessinateur tchèque Kája Saudek
Authors: Fromont Garance 
Published: September 2023

La période de la guerre froide est souvent pensée comme celle d’une non-porosité entre l’Ouest et l’Est. Cependant, des objets culturels découverts avant l’instauration de gouvernements socialistes continuent de circuler. À partir de l’oeuvre de l’auteur tchèque Kája Saudek, nous nous proposons d’étudier comment les comic strips américains ont été adaptés, retravaillés et transformés en Tchécoslovaquie communiste dans les années 1960. Saudek a collaboré à un classique du cinéma populaire tchèque, Kdo chce zabít Jessii? (Qui veut tuer Jessie?), réalisé par Václav Vorlíček. À la même époque, il se lance dans un projet plus personnel, Muriel a andělé (Muriel et les Anges), scénarisé par l’écrivain Miloš Macourek et inspiré de la bande dessinée française Barbarella. Cet article revient sur l’oeuvre atypique d’un monument de la bande dessinée tchèque, au carrefour de diverses influences dans un monde coupé en deux.
Dante global : adaptations, transpositions, transnationalisations d’un imaginaire « pop »
Authors: Benucci Alessandro 
Published: September 2023

Cet article s’intéresse aux nombreuses adaptations en bandes dessinées de La divine comédie de Dante Alighieri parues en Italie et dans plusieurs pays (France, Pays-Bas, Allemagne, États-Unis, Japon) aux xxe et xxie siècles. Ce phénomène majeur d’un univers médiatique en pleine expansion – le « Dante pop » – est interprété selon deux approches théoriques complémentaires. D’une part, les critères régissant le détournement parodique selon la pensée structuraliste (Genette, Kristeva, Hutcheon) permettent de saisir les enjeux culturels soulevés par les reprises bédéiques italiennes ; d’autre part, les réflexions menées autour des notions de transculturalité (De Toro) et de transmédialité (Rajewsky) mettent en valeur quelques tendances communes aux bandes dessinées inspirées de L’enfer de Dante et diffusées sur le marché éditorial français, telles que les processus d’actualisation des personnages, les trames narratives promues par l’industrie culturelle, l’évolution transnationale de la signification attribuée à l’adjectif « dantesque ».
Humanitarian Numbers in the Russian–Ukrainian War
Authors: Lawson Brendan , Glasman Joël , Mützelburg Irina 
Published: September 2023

In this interview, Irina Mützelburg discusses the production and spreading
of humanitarian numbers in the on-going Russian–Ukrainian war since
February 2022. She traces the emergence of the announced number of Ukrainian
refugees several months before the beginning of the full-scale invasion and
analyses the ways in which the United Nations High Commissioner for Refugees
(UNHCR) and the International Organization for Migration (IOM) compile
statistics respectively on Ukrainian refugees abroad and internally displaced
persons (IDPs). Numbers are produced to be coherent and higher, to illustrate
the need for attention and funding. Furthermore, the debated issue of Ukrainians
who (were) moved to Russia since the invasion is reviewed, discussing not only
the numbers, but also the ways the Ukrainian and the Russian states frame the
ways and reasons for which Ukrainians came to Russia. Finally, the interview
covers the term ‘evacuee’ and ‘evacuation’ that both
Russian and Ukrainian politicians and media use in unusual ways and which have
been taken up by international media outlets.
Irina Mützelburg is a post-doctoral researcher at the Centre for East
European and International Studies in Berlin and a co-coordinator of the
German-French ANR-DFG project, Limspaces, researching everyday life in Moldova
and Ukraine. Currently she studies the educational situation of displaced pupils
from Ukraine in Germany. She holds a PhD from Sciences Po Paris and has
published on Ukraine, migration policies, norm transfer and public policy
analysis in the Journal of Intercultural Studies, European Journal of
Migration, Revue française de science politique,
Revue d’études comparatives Est-Ouest,
Revue Gouvernance and Trajectoires. Her
book Transferring Asylum Norms to EU Neighbours: Multi-Scalar Policies
and Practices in Ukraine has been published with Palgrave Macmillan
(London) in 2022.
Technology Enhanced Learning: Utilization of SymboLab Manipulative Instruction and Performance of Students in Quadratic Graphs
Authors: Akpan Ekemini T. , Charles-Ogan Gladys I. , Eze Foluke B. , Okafor-Agbala Uzoamaka C. , Onyeka Edith C. 
Published: September 2023

Twenty first century learners are digital citizen and technologically savvy. This demands the use of innovative teaching strategies that take leverages of the affordance of digital tools. In this study, the effects of SymboLab manipulative instruction on students’ performance in quadratic graph has been investigated. Three research questions and three hypotheses guided the study. The population of study consisted of all senior secondary one students across schools in Uyo metropolis, and a sample size of one hundred (100) students were purposively selected from the population. The instruments for data collection was Quadratic Performance Test. The validated instrument by experts yielded a reliability coefficient of 0.81, by method of Kuder-Richardson-21 formula. Quasi-experimental design was used for the study. Two intact classes were assigned to experimental group and a control group. The first experimental group were taught the concept of quadratic graph using SymboLab Manipulative Instruction, while the control group were taught quadratic graph using Concrete Manipulative Instruction. Data obtained from the study was analyzed using mean, percentages and Analysis of Covariance. The results showed that students taught quadratic graph using technology enhanced learning tool; SymboLab Manipulatives performed significantly higher than those taught using Concrete Manipulative. Gender exerted a non-significant influence on students’ performance in quadratic graph between the intervention groups. Moreover, the joint effect of gender and instructional manipulatives yield non-significant influence on students’ performance in the concept of quadratic graph. It was therefore recommended that technology enhanced learning tools such as SymboLab Manipulatives should be used to teach the concept of quadratic graphs in secondary schools.
Enhancing Yield and Biological Efficiency of Volvariella volvaceae through Non-Conventional Cultivation Methods
Authors: Gopinath V.  , Elangovan M. , Thakur Nisha , Biswas M. K. 
Published: September 2023

A study was conducted to determine the impact of Different Non- Conventional methods of Cultivation on yield and biological efficiency of Volvariella volvaceae. Among the different methods viz., bed method, partial compost method (3 days), partial compost method (6 days), partial compost method (9 days), intact straw + partial compost, Chopped paddy straw in polythene bags, Rolled paddy straw in polythene bag were experimented on yield and biological efficiency. However, the bed method of cultivation proved its well suitability among all the methods tested and gave highest yield and biological efficiency (1920 g and 15.0%) followed by partial compost method (3 days), single layer of straw + partial compost, partial compost (6 days) which exhibited (1025 g and 10.25%), (840 g and 8.40%) and (720 g and 7.20%) respectively. Maximum average weight of sporophore (24.6 g) was observed from bed method of cultivation which was significantly superior amongst all the methods evaluated followed by partial compost (3 days), single layer of straw + partial compost, partial compost (9 days) at 18.30 g, 16.15g and 15.5 g respectively. Smaller sizes of sporophores were noticed on partial compost (6 days) at average weight of 15 g. Average weight of sporophores noticed in chopped paddy straw and rolled paddy in polythene bag method were 12.2 g and 10 g respectively. Considering the major drawback of Volvariella that it has very low biological efficiency, bag method of cultivation was aimed to increase the biological efficiency of paddy straw mushroom.
Advancing Cloud Technology Security: Leveraging High-Level Coding Languages like Python and SQL for Strengthening Security Systems and Automating Top Control Processes
Authors: Olabanji Samuel Oladiipo 
Published: September 2023

In today's dynamic business environment, staying ahead of competitors requires the integration of cutting-edge technologies into organizational processes. Cloud Computing, a transformative technological advancement, offers a promising avenue for achieving operational efficiency and innovation. This paper explores the integration of Cloud Computing with two powerful coding languages, Python and SQL, to enhance cloud security and automate control processes. Cloud Computing's adoption has revolutionized resource management through virtualization and diverse computing models. However, it also introduces security challenges like data breaches and unauthorized access. Python and SQL emerge as essential tools for addressing these challenges and automating various control processes. Python's versatility empowers organizations to establish sophisticated security protocols and automate tasks such as intrusion detection, anomaly detection, real-time monitoring, and computer vision. On the other hand, SQL's role involves automating control processes like resource provisioning, scaling, backup, recovery, access control, and database management.
Integrating Python and SQL offers a holistic approach to cloud security enhancement. However, challenges such as skill set requirements, code quality, integration, maintenance, scalability, monitoring, and data privacy must be addressed. Fortunately, solutions like Snowpark, dbt, Hex, and Dataiku provide platforms that unify various programming languages, fostering collaboration and streamlining tasks. This convergence of Cloud Computing with Python and SQL presents numerous benefits. Automation enhances efficiency, reduces human error, and ensures consistent control process execution. This synergy allows organizations to achieve scalability, cost savings, improved security, and comprehensive monitoring and reporting.
As institutions increasingly d on Cloud Computing to drive innovation and competitiveness, the importance of fortifying these systems against evolving threats cannot be overstated. Integrating Python and SQL represents a pivotal juncture in achieving this goal. By harnessing their combined power, organizations can create robust security mechanisms, streamline operations, and promote cross-functional collaboration. As the digital landscape evolves, embracing this approach is crucial for sustaining success in a rapidly changing environment.
Change in Purpose in Life Before and After Onset of Cognitive Impairment
Authors: Sutin Angelina R. , Luchetti Martina , Stephan Yannick , Terracciano Antonio 
Published: September 2023

ImportancePurpose in life is a critical aspect of psychological well-being that is associated with better cognitive outcomes across the continuum of dementia. To our knowledge, the natural history of purpose with onset of cognitive impairment has yet to be evaluated.ObjectiveTo evaluate changes in purpose in life prior to and after onset of cognitive impairment.Design, Setting, and ParticipantsThis cohort study used assessments of purpose in life and cognitive status from March 2006 to May 2021 in the Health and Retirement Study (HRS) and from May 2011 to November 2021 in the National Health and Aging Trends Study (NHATS).ExposureCognitive impairment at each wave based on established thresholds in HRS and NHATS.Main Outcomes and MeasuresThe main outcome was purpose in life, measured with the Ryff Measures of Psychological Well-Being in HRS and a validated item in NHATS.ResultsIn HRS, 22 668 participants provided 50 985 assessments of purpose across all waves. In NHATS, 10 786 participants provided 53 880 assessments of purpose across all waves. In HRS, 58.3% of participants were female, with mean (SD) age of 64.76 (10.41) years at baseline; in NHATS, 57.4% were female, with mean (SD) age of 76.82 (7.71) years at baseline. Across waves, 6794 HRS participants (30%) and 4446 NHATS participants (41.2%) were in the cognitive impairment range. Accounting for demographic covariates and normative change in purpose, multilevel modeling indicated that standardized purpose in life declined significantly prior to onset of cognitive impairment (estimate for 10 years) in both HRS (b = −0.12; 95% CI, −0.17 to −0.07; P &amp;lt; .001) and NHATS (b = −0.10; 95% CI, −0.20 to −0.01; P = .03). Purpose declined significantly more rapidly following onset of cognitive impairment, with a standardized decline nearly 3 times larger compared with prior to impairment in HRS (b = −0.35; 95% CI, −0.41 to −0.29; P &amp;lt; .001) and 4 times larger in NHATS (b = −0.44; 95% CI, −0.53 to −0.34; P &amp;lt; .001).Conclusions and RelevanceIn this cohort study, purpose in life declined with emergence of cognitive impairment. The decline before onset was too small to be useful to detect impending impairment in clinical settings. The steeper decline following impairment suggests that individuals are aware that their purpose is declining. Purpose may be an intervention target following cognitive impairment to maintain well-being and to reduce or slow emergence of behavioral symptoms associated with low purpose.
Pediatric Cervical Spine Injury Following Blunt Trauma in Children Younger Than 3 Years
Authors: Luckhurst Casey M. , Wiberg Holly M. , Brown Rebeccah L. , Bruch Steven W. , Chandler Nicole M. , Danielson Paul D. , Draus John M. , Fallat Mary E. , Gaines Barbara A. , Haynes Jeffrey H. , Inaba Kenji , Islam Saleem , Kaminski Stephen S. , Kang Hae Sung , Madabhushi Vashisht V. , Murray Jason , Nance Michael L. , Qureshi Faisal G. , Rubsam Jeanne , Stylianos Steven , Bertsimas Dimitris J. , Masiakos Peter T. 
Published: September 2023

ImportanceThere is variability in practice and imaging usage to diagnose cervical spine injury (CSI) following blunt trauma in pediatric patients.ObjectiveTo develop a prediction model to guide imaging usage and to identify trends in imaging and to evaluate the PEDSPINE model.Design, Setting, and ParticipantsThis cohort study included pediatric patients (&amp;lt;3 years years) following blunt trauma between January 2007 and July 2017. Of 22 centers in PEDSPINE, 15 centers, comprising level 1 and 2 stand-alone pediatric hospitals, level 1 and 2 pediatric hospitals within an adult hospital, and level 1 adult hospitals, were included. Patients who died prior to obtaining cervical spine imaging were excluded. Descriptive analysis was performed to describe the population, use of imaging, and injury patterns. PEDSPINE model validation was performed. A new algorithm was derived using clinical criteria and formulation of a multiclass classification problem. Analysis took place from January to October 2022.ExposureBlunt trauma.Main Outcomes and MeasuresPrimary outcome was CSI. The primary and secondary objectives were predetermined.ResultsThe current study, PEDSPINE II, included 9389 patients, of which 128 (1.36%) had CSI, twice the rate in PEDSPINE (0.66%). The mean (SD) age was 1.3 (0.9) years; and 70 patients (54.7%) were male. Overall, 7113 children (80%) underwent cervical spine imaging, compared with 7882 (63%) in PEDSPINE. Several candidate models were fitted for the multiclass classification problem. After comparative analysis, the multinomial regression model was chosen with one-vs-rest area under the curve (AUC) of 0.903 (95% CI, 0.836-0.943) and was able to discriminate between bony and ligamentous injury. PEDSPINE and PEDSPINE II models’ ability to identify CSI were compared. In predicting the presence of any injury, PEDSPINE II obtained a one-vs-rest AUC of 0.885 (95% CI, 0.804-0.934), outperforming the PEDSPINE score (AUC, 0.845; 95% CI, 0.769-0.915).Conclusion and RelevanceThis study found wide clinical variability in the evaluation of pediatric trauma patients with increased use of cervical spine imaging. This has implications of increased cost, increased radiation exposure, and a potential for overdiagnosis. This prediction tool could help to decrease the use of imaging, aid in clinical decision-making, and decrease hospital resource use and cost.