bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thermodynamics of continental deformation
Authors: Kumar Ajay , Cacace Mauro , Scheck-Wenderoth Magdalena 
Published: August 2023

Abstract
Plate tectonics theory postulates the existence of rigid mobile plates. However, what defines and controls their internal deformation, particularly within continents, is not yet fully understood. Using data-driven thermomechanical modelling of the Alpine Himalayan Collision Zone, we hypothesize that deviations from an equilibrium between mantle dynamics, plate-boundary forces, and thermochemical configuration of the lithosphere controls continental deformation. We quantify such balance between the internal energy of the plate and tectonic forces in terms of a critical crustal thickness, that match the global average of present-day continental crust. It follows that thicker intraplate domains than the critical crust (orogens) must undergo weakening due to their increased internal energy, and, in doing so, they dissipate the acquired energy within a diffused zone of deformation, unlike the localized deformation seen along plate boundaries. This evolution is controlled by a dissipative thermodynamic feedback loop between thermal and mechanical relaxation of the driving energy in the orogenic lithosphere. Exponentially growing energy states, leading to runaway extension are efficiently dampened by enhanced dissipation from radioactive heat sources. This ultimately drives orogens with their thickened radiogenic crust towards a final equilibrium state. Our results suggest a genetic link between the thermochemical state of crust and the tectonic evolution of silicate Earth-like planets.
Energy Efficient Cluster Head Selection Using Cognitive Radio in WSN
Authors: thaseen Aliya , Anusha A , Punithavathi I. s. Hephzi , Nazeer Mohd , Obulesh A. 
Published: August 2023

Abstract
In this paper, taking account of the number of channel allocation and the quality of spectrum channels from the global and the instant point of view, we propose two CSN routing metrics. In the first routing metric, the delivery success probability through all possible channels is defined in the constraint that only one retransmission is permitted to reduce rerouting. Similarly, the second routing metric considers the average transmission delay overall possible channels are presented. Based on the two routing metrics, the related routing algorithms are then designed, in which the optimal route is determined in an ON-demand route style. To increase the practicability, the channel assignments are not permanent and any relay nodes carrying packets could choose the channel with the largest routing metric at that time. We conduct extensive simulations, which validates the route performance of our routing schemes compared with other CSN routing protocols. It has been proved that proposed protocols reduces the number of re transmission and delay and increases the throughput compared to the existing routing protocols.
Characteristics of Peripheral refractive errors in Eyes of Patients with Non- amblyopic Myopic Anisometropia
Authors: Tong Gengmin , Jin Yuanhui , Wu Hongyan , Zhou Yao 
Published: August 2023

Abstract
Background
This study aims to investigate relative peripheral refractive (RPR) characteristics in children with non-amblyopic myopic anisometropia and explore potential associations between relative peripheral refractive errors (RPRE) and myopia.
Methods
Relative peripheral refractive errors were assessed in 64 children diagnosed with non-amblyopic myopic anisometropia utilizing multispectral refraction topography (MRT). Evaluated parameters encompassed total defocus values (TRDV), defocus values at eccentricities spanning 0 to 15 degrees (RDV-15), 0 to 30 degrees (RDV-30), 0 to 45 degrees (RDV-45), as well as superior (RDV-S), inferior (RDV-I), temporal (RDV-T), and nasal (RDV-N) positions.
Results
The study revealed a noteworthy contrast in TRDV values between Group ME (0.52 ± 0.36) and Group FE (0.17 ± 0.41), with a substantial significance (P < 0.0001). While no significant RDV-15 difference emerged between Group ME (0.01 ± 0.05) and Group FE (-0.01 ± 0.07) (P > 0.05), a meaningful RDV-30 difference existed between Group ME (0.11 ± 0.14) and Group FE (0.03 ± 0.19) (P = 0.0017). A significant discrepancy in RDV-45 was also observed between Group ME (0.39 ± 0.29) and Group FE (0.13 ± 0.34) (P < 0.001). Notably, RDV-I and RDV-T positions demonstrated marked differences between Group ME and Group FE (P < 0.0001), whereas no significant disparity was noted in RDV-S and RDV-N positions (P > 0.05).
Conclusion
Eyes exhibiting greater myopia manifested more hyperopic peripheral defocus in the context of anisometropia. MRT as a novel ophthalmic evaluation technique, holds promising potential for broader clinical applications in the future.
Removal of Heavy metal ions using Nano-cellulose prepared from rice husk: Validation by Differential Pulse Voltammetry
Authors: Baraskar P. N. , Samant R. A. , Gurav V. L. 
Published: August 2023

Abstract

In this work Cellulose was extracted from rice husk and chemically modified to produce Nano-Cellulose. It was characterized by FTIR, XRD, SEM/EDS, TEM, BET surface area analyzer, Particle size analyzer and tested for the removal of metal ions i.e. Zn(II), Cd(II), As(III),Pb(II) and Sn(II) from aqueous solution. The removal method was validated by differential pulse voltammetry (DPV). Adsorption experiment was performed to investigate effects of initial pH, adsorbent dose, contact time and initial concentration of heavy metal ions on the adsorption capacity of nanocellulose. The experimental results revealed that the removal of metal ions on the nanocellulose was a pH-dependent process with the maximum adsorption capacity at the initial solution pH of 5–6. Adsorbent dose of 8mg/mL was sufficient for effective adsorption. In addition, the kinetics and equilibrium data are well described by pseudo-second-order kinetics and the Freundlich adsorption isotherm model at 50 min contact time and 50 mg/L initial concentration. Moreover, the desorption and re-adsorption performance was also studied, and the results revealed that the Nano-cellulose still showed good adsorption performance up to eight cycles of regeneration.
Development and psychometric properties testing of the educational need- assessment questionnaire for army healthcare providers to provide care for mothers and newborns in disasters
Authors: Poursoleiman Leila , Pishgooie Amir hosein , Aliyari SHahla , Sharififar Simin Taj 
Published: August 2023

Abstract
Background
To develop a curriculum for healthcare providers to provide care for mothers and newborns in disasters, they must first assess educational needs and then develop training content based on educational needs. This study aimed to construct and assess the validity and reliability of the educational need-assessment questionnaire for healthcare providers for mothers and newborns in disasters.
Methods
In this methodological study, after conducting web and library studies and cultural attention, a questionnaire was set up, and face validity, content validity, and construct validity were assessed. Second, internal constancy and stability were measured as a function of reliability. At this stage of the study, 208 healthcare providers from selected hospitals in the city of Tehran were selected and participated. SPSS version 16 was used for data analysis.
Results
The questionnaire was developed into 64 items. The face and content validities were acceptable. Exploratory factor analysis was fitted and showed ten factors. All of the items in a factor were compatible with each other, so the items were put into ten factors, and choosing the fit name for each factor was possible. These 10 factors explained 75/3% of the total variance of the test. The total scale showed an alpha Cronbach of 0/94.
Conclusion
The findings indicate that the current questionnaire entitled "Educational needs assessment for healthcare providers for mothers and newborns in disasters" with 64 items has appropriate reliability and validity and can be used in different settings by curriculum planners as a suitable tool for assessing the educational needs of healthcare providers for mothers and newborns in disasters.
Genetic parameters and responses associated with high temperature in potato wild relatives.
Authors: Bashir Ikram , Nicolao Rodrigo , Shimoia Eduardo Pereira , Amarente Luciano do , Castro Caroline Marques , Heiden Gustavo 
Published: August 2023

Abstract
Crop wild relatives (CWRs) have significantly been used in potato (Solanum tuberosum, Solanaceae) breeding. Hence, introgression breeding may help in coping with the challenges posed by climate change. We used 20 accessions from Embrapa Potato Genebank, twelve belongs to wild specie Solanum chacoense and eight from S. commersonii and one, S. tuberosum commercial cultivar for their tolerance to two different temperature conditions CT as control temperature (14–24ºC) and HS as heat stress (24–37ºC). The evaluation was based on gas exchange (Pn, Gs and Tr), chlorophyll fluorescence analysis (Y(II), NPQ, Fv/Fm), chlorophyll A, B and carotenoid content and tuber yield related traits (FTW and DMC%) and measured after 1DAS (Days after stress), 15DAS and 35DAS. Mixed model methodologies were used to predict average genotypic value in the various environments and capitalize on an average interaction with all evaluated environments. Significant differences were observed between Solanum wild genotypes showed by 2-factorial for agronomic traits and 3-factorial ANOVA for physiological traits. The correlations among the accessed traits were found here significant for heat stress conditions. Mixed model methodology helps us ranking the genotypes based on measured variables according to their true genotypic values for both temperature conditions and after each measurement of days after applied stress.
Phytochemical investigation of anti-proliferative active fractions of Cannabis sativa leads to isolate a new Compound Canniprene A and other bioactive compounds through bioassay guided fractionation and HPLC assisted purification
Authors: Nalli Yedukondalu , Bharti Sahil , Amin Tanzeeva , Singh Rohit , Behera Jayaprakash , Goswami Anindya , Verma Mahendra Kumar 
Published: August 2023

Abstract
Phytocannabinoids and synthetic cannabinoids have been explored as the lead due to their anti-proliferative nature and can be anti-cancer agents. These were found to activate numerous pharmacological targets to generate new therapies in alleviating specific symptoms or delaying the disease of Cancer. However, the comprehensive anti-cancer activities of cannabinoid acids and non-cannabinoids are not fully explored. Herein we report simple extraction, faster bioassay-guided fractionation, and HPLC-assisted purification of bioactive secondary metabolite and their identification. Anti-proliferative activity of six cannabinoid acids (CBDA’s) and eleven non-cannabinoids from the leaves of Cannabis sativa was evaluated. HPLC- assisted purification from the bioactive fractions leads to isolate one new compound Methoxy Canniprene (methoxy isoprenyl bibenzyl), including all six CBDA’s eleven non-cannabinoids in a single step, and NMR, HR-ESI-MS studies, and comparison with the literature data authenticated their structures. The crude extract (IC50 range: 18.0–37.2 µg/mL), Fraction A to D (11.9 to 222 µg/mL), and purified different cannabinoid and non cannabinoids (IC50 range: 0.5–100 µM) displayed potent anti-proliferative activities against almost all the tested five human cancer cell lines.
The contribution and interplay of implicit and explicit processes on physical activity behavior: Empirical testing of the Physical Activity Adoption and Maintenance (PAAM) model
Authors: Jekauc Darko , Gürdere Ceren , Englert Chris , Strobach Tilo , Bottesi Gioia , Bray Steven , Brown Denver , Fleig Lena , Ghisi Marta , Graham Jeffrey , Martinasek Mary , Tamulevicius Nauris , Pfeffer Ines 
Published: August 2023

Abstract

The adoption and maintenance of physical activity (PA) is an important health behavior. This paper presents the first comprehensive empirical test of the Physical Activity Adoption and Maintenance (PAAM) model, which proposes that a combination of explicit and implicit self-regulatory processes is involved in PA adoption and maintenance. Data were collected via online questionnaires in English, German, and Italian at two measurement points four weeks apart. The study included 422 participants (Mage= 25.3, SDage= 10.1; 74.2% women) from Germany, Switzerland, Italy, Canada, and the U.S. The study results largely supported the assumptions of the PAAM model, indicating that intentions and habits significantly mediate the effects of past PA on future PA. In addition, the effect of past PA on future PA was shown to be significant through a mediation chain involving affect and habit. Although the hypothesis that trait self-regulation moderates the intention-behavior relationship was not supported, a significant moderating effect of affect on the same relationship was observed. The results suggest that interventions targeting both explicit and implicit processes may be effective in promoting PA adoption and maintenance.
The use of the Baumber scoring system for metastatic disease of the vertebral column
Authors: Hodgson Sam , Pynsent Paul , Hughes Simon , Rehousek Petr , Gardner Adrian 
Published: August 2023

Abstract
Objective
The prognostic assessment of patients with metastatic spinal disease is predominantly tumour rather than patient based. Baumber et al have published a prognostic scoring system based on the patient rather than the tumour for metastatic disease of the appendicular skeleton. This paper assesses that formula for metastatic disease of the spine.
Results
Survival was recorded for 65 individuals who underwent surgery for metastatic disease of the spine. Using the same parameters as Baumber, the projected survival was longer than that recorded in their cohort (over-prediction of 39% at 6 months and 54% at 12 months). The relative contributions of the individual parameters as part of the overall survival was different between the groups with a greater contribution seen if the individual had hyponatraemia, hypoalbuminaemia and low levels of creatinine. The reasons for the differences seen between the spinal and appendicular groups with regards to these parameters are not clear but may represent a poorer level of general health. Further work is required to develop a specific tool for the calculation of prognosis in a metastatic spinal cohort using a general health perspective.
End-on Versus Parallel Radiofrequency Lesioning for Neurotomy of the Cervical Medial Branch Nerves: A Study Protocol of a prospective, randomized, Double-Blind Clinical Trial: The “EndPaRL” Study
Authors: Alomari Abeer , Ferreira-Dos-Santos Guilherme , Singh Mandeep , Burnham Taylor , Cao Xingshan , McCormick Zachary , Flamer David , Kumar Pranab , Hoydonckx Yasmine , Khan James S. , Bhatia Anuj 
Published: August 2023

Abstract
Background
Cervical facet joint disease is a common source of neck pain and its prevalence increases with aging. Conservative multimodal management options (e.g., strengthening of neck muscles, non-steroidal anti-inflammatory medications, massage, and thermal modalities) often fail to relieve pain. Cervical medial branch nerve (CMBN) radiofrequency neurotomy (RFN) is an effective minimally invasive technique for treating chronic neck pain secondary to facet joint disease. An end-on approach for this procedure has been proposed that may be technically easier and require less time while reducing post-procedural discomfort. The protocol presented here is for a study that aims to compare the efficacy of a new end-on approach using multi-tined cannulae, against the conventional parallel technique that employs straight cannulae for RFN of the CMBN in patients with chronic neck pain due to cervical facet joint disease.
Methods
A multicentre randomized, non- inferior, active comparator-controlled trial will be conducted with two parallel groups and blinding of participants and outcome assessor. The study will include 72 adults with chronic neck pain secondary to facet joint disease who are candidates for RFA of the CMBN. Participants will be randomized to either the conventional parallel or the end-on approach in a 1:1 ratio. The intensity of pain and pain-related domains (function, quality of life, sleep, adverse effects of the interventions, analgesic intake) will be measured at one, three, six, and 12 months after the procedure.
Discussion
Neck pain secondary to cervical facet joint disease is prevalent and RFA of the CMBN is a validated treatment for relieving it. The conventional parallel technique can be technically challenging, and it can be associated with adverse effects while the newer end-on approach has the potential of being a simpler technique with less adverse effects. This trial will be the first non-inferiority study to compare the clinical efficacy of the end-on approach against the conventional parallel approach for RFN of CMBN in patients with chronic neck pain due to cervical facet joint disease.
Trial registration
ClinicalTrials.gov NCT05818774. Registered on April 20, 2023
Prognostic Factors of Oligometastasis after Stereotactic Body Radiotherapy: Real-world Utility of the European Society for Radiotherapy and Oncology/European Organisation for Research and Treatment of Cancer Classification
Authors: Bessyo Ryosuke , Uezono Haruka , Ota Yosuke , Miyazaki Shuichiro , Marudai Mitsuru , Takabayashi Hatamei , Tsujino Kayoko 
Published: August 2023

Abstract
Background
The efficacy of local therapy for oligometastatic disease (OMD) remains unclear. This study aimed to evaluate the prognostic utility of the classification system for OMD and explore which groups may benefit from stereotactic body radiation therapy (SBRT).
Methods
The single-center retrospective study included 48 patients (55 sites) with solid tumors and 1–3 extracranial oligometastases, who underwent SBRT for all metastases at our institution between January 2018 and December 2021. OMD states were classified based on the European Society for Radiotherapy and Oncology and European Organisation for Research and Treatment of Cancer classification system. Local control (LC), overall survival (OS), and progression-free survival (PFS) for each group were analyzed using the Kaplan–Meier method. Acute and late adverse events (AEs) were evaluated.
Results
The median follow-up period was 14 months (range, 0–48 months). The number of patients in the de-novo, repeat, and induced OMD groups were 16, 19, and 13, respectively. The LC rates at 1-year for the entire, de-novo, repeat, and induced cohorts were 87.9%, 88.2%, 90.9%, and 83.9%, respectively. The 1-year PFS and OS for each group were 38.9%, 81.2%, and 61.0% and 87.1%, 29.9%, and 80.8%, respectively. Grade 2 or higher AEs occurred in five patients (10.4%). No grade 4 or 5 AEs were observed.
Conclusions
SBRT in patients with OMD was safe and highly effective for local control. Patients with repeat OMD demonstrated better PFS than other OMDs.
Outcomes of adult native liver survivors with biliary atresia: the current situation in Japan
Authors: Kawaguchi Yunosuke , Terui Keita , Takenouchi Ayako , Komatsu Shugo , Saito Takeshi , Hishiki Tomoro 
Published: August 2023

Abstract
Purpose: This study aimed to elucidate the difficulties faced by adult native liver survivors with biliary atresia (BA) in Japan.
Methods: A single-center, retrospective, observational study of 57 adult patients with BA was conducted. The clinical course of BA was compared between native liver survivors and non-survivors who reached adulthood. Indications and outcomes of liver transplantation (LT) among non-survivors were assessed.
Results: A significantly larger portion of non-survivors (n=10) met the criteria for LT
(p <0.001) and received treatment for portal hypertension after reaching 20 years of age (p <0.01) compared with the survivors. Causes of death included liver cirrhosis (n=8), graft failure of living donor liver transplantation (LDLT) (n=1), and hepatocarcinoma (n=1). Two of the non-survivors who died of liver cirrhosis had no indication for LT because of alcohol dependence and uncontrolled infection. An appropriate donor candidate could not be found for the five patients who opted for LDLT. All six patients waitlisted for deceased donor liver transplantation (DDLT) died after a median waiting period of 17 months.
Conclusion: Adult BA patients in Japan have limited options for LT, mainly owing to low donor candidate availability for LDLT and a low prevalence of DDLT.
A Bioinformatic Analysis Reveals Commonly Dysregulated Genes and Pathways in Multiple Cancers Treated with Metformin
Authors: Rahmani Mohammadreza , Jalili Ali , Moradzad Mohammad , Fakhari Shohreh 
Published: August 2023

Abstract
Metformin, a prescribed medication for diabetes, has exhibited anti-cancer effects. In this study, we conducted an extensive bioinformatic analysis aiming to reveal effects of metformin on gene modulation in four distinct types of cancer: head and neck, liver, pancreatic, and prostate cancer. By integrating publicly available gene expression data from Gene Expression Omnibus (GEO) and enrichment analysis methods, we identified genes and pathways associated with the anti-cancer activities of metformin. We observed a significant upregulation of the genes NFKBIA and GADD45A, which are known to be involved in pathways linked to cancer progression. Moreover, we identified that MTHFD2 appears to be a biomarker for all these types of cancers and a target for metformin. Furthermore, the gene DKK1 exhibited potential as a prognostic indicator specifically for head and neck and pancreatic cancer, highlighting its clinical importance in these cancer types. In conclusion, our bioinformatic analysis suggests that metformin possesses anti-cancer activities through modulations of the NFKBIA, GADD45A, MTHFD2, and DKK1 genes which our study reveals for the first time their association with metformin in context of cancer. Our data contribute to understanding of the mechanism of anti-cancer activity of metformin.
Computer vision-based monitoring method of non-wearing helmet events using face recognition
Authors: Liao Chenrui , Chen Hongyan , Liu Chenxi , Yu Ying , Zhao Pengfei 
Published: August 2023

Abstract
Wearing helmets is crucial for ensuring the safety of workers in the construction industry because this is the first line of avoiding over 70% of production safety accidents. However, many workers are not willing to wear helmets due to discomfort and reduced work efficiency. To this end, this paper proposes a computer vision-based monitoring method using face recognition to detect and prevent non-wearing helmet events on construction sites. Compared to existing surveillance or monitoring systems, the proposed method has three significant advantages. Firstly, by using a unique structure, the proposed method can achieve up to 97.7% accuracy in detecting workers not wearing helmets. Secondly, the proposed method enables real-time detection, allowing it to prevent dangerous behaviors by stopping them in advance. Finally, the proposed method has been successfully deployed on over 20 real construction sites, and it has detected more than 18,000 related events.