bluuebunny/crossref_metadata_2025_split huggingface dataset:
Jules Verne, un mécontemporain ?
Authors: Fabre Michel 
Published: February 2023

On fait souvent de Jules Verne un chantre de la modernité, mais son enthousiasme pour les prouesses techniques est toujours tempéré par un pessimisme de fond concernant les dégâts du progrès. Comment penser l’ambiguïté de la modernité chez Verne ? On propose ici un voyage au centre de l’écriture vernienne qui découvre successivement trois couches géologiques de l’œuvre. Déjà le niveau narratif oppose des héros et antihéros, des lieux, des objets et des machines bénéfiques ou maléfiques. En poursuivant l’exploration, on s’aperçoit que ces personnages et ces intrigues revêtent une dimension mythologique centrée sur les figures de Prométhée et de Faust. Enfin, il faut descendre, sous les intrigues et les figures, pour déceler les schèmes élémentaires d’involution et d’explosion qui dynamisent l’imaginaire des Voyages extraordinaires et que traduit l’opposition de la coquille et du volcan. Verne n’est pas un auteur de science-fiction, mais plutôt d’anticipation sociopolitique : il décrit, en visionnaire, l’ambiguïté de notre modernité que bien des philosophes du XX e siècle tenteront de conceptualiser.
Compétence, adaptation, compétition. De Spinoza à Darwin, les cercles contextuels absents
Authors: Legeay Vincent 
Published: February 2023

Ce travail consiste en une généalogie philosophique de la notion de « compétence » en regard de celle d’« adaptation », depuis le XVII e siècle, de Hobbes et Spinoza à Darwin. Il s’agit d’en tirer un certain nombre d’enseignements épistémologiques critiques pour les usages scolaires contemporains de ces notions, dont l’ambivalence peut être clarifiée.
Application of next-generation sequencing in thalassemia screening
Authors: Fang Xingyi , Gong Yi , Ma Yanlin , Huang Yuanhua 
Published: February 2023

Objective:
To evaluate the value of next-generation sequencing (NGS) in the prevention and management of thalassemia.

Methods:
A systematic search was performed in eight databases including China Biomedical Literature Database, Chinese National Knowledge Infrastructure, Chinese Scientific Journals Database, Wanfang database, PubMed, EMBASE, Web of Science, and Cochrane Library from the inception to 1 June 2022. Stata 17.0 and Review Manager 5.4 were used for the meta-analysis.

Results:
Nine studies containing 14794 participants were included in the meta-analysis. Compared with the routine genetic testing (including Gap-PCR and reverse dot blot), NGS had higher detection rates in screening thalassemia (RR 1.22, 95% CI 1.13-1.31, P<0.01), particularly for the α-thalassaemia mutation carriers (RR 1.24, 95% CI 1.07-1.44, P<0.01). However, no significant difference was found in the screening of β-thalassemia (RR 1.10, 95% CI 0.99-1.23, P>0.05).

Conclusions:
Compared with routine genetic testing, NGS had a higher detection rate in general, particularly in the detection of α-thalassemia.
Treatment outcomes and adverse drug reactions among patients with drug–resistant tuberculosis receiving all-oral, long–term regimens
Authors: Aslam Hira , Omar Asad , Fatima Razia , Rasool Usman , Yaqoob Aashifa , Ullah Waseem , Khan Aamir , Khan Yusra Habib , Mallhi Tauqeer Hussain 
Published: February 2023

Objective:
To assess the effectiveness and adverse drug reactions of all-oral regimens for patients with multidrug-resistant tuberculosis.

Methods:
This retrospective study was conducted at 10 Programmatic Management of Drug Resistant Tuberculosis sites in Punjab province of Pakistan. Patients receiving treatment for drug resistant tuberculosis from July 2019 to December 2020 with at least interim result i.e. 6th month culture conversion or final outcomes (cured, complete, lost to follow-up, failure, death) available, were included in the study. Data was extracted from electronic data management system. For the reporting and management of adverse drug events, active tuberculosis drug safety monitoring and management was implemented across all sites. All the data was analyzed using SPSS version 22.

Results:
Out of 947 drug resistant tuberculosis patients included in this study, 579 (68%) of the patients had final outcomes available. Of these, 384 (67.9%) successfully completed their treatment. Out of 368 (32%) patients who had their interim results available, all had their 6th month culture negative. Combining new medications was thought to result in serious adverse outcomes such as QT prolongation. However, this study did not record any severe adverse events among patients.

Conclusions:
All-oral regimens formulation guided by overall treatment effectiveness resulted in treatment outcomes comparable to those obtained with traditional injectable treatment.
Risk Factors for ERCP-related Complications and what is the specific role of ASGE Grading System
Authors: Shavakhi Ahmad , Zobeiri Mehdi , Khodadoostan Mahsa , Zobeiri Mohammad Javad , Shavakhi Alireza 
Published: February 2023

Background:
Endoscopic retrograde cholangiopancreatography (ERCP) is one of the main therapeutic and sometimes diagnostic methods in biliary and pancreatic diseases. A grading system for the difficulty of ERCP (grade one to four, the higher grade represents the more complexity of the procedure) has been developed by the American Society for Gastrointestinal Endoscopy (ASGE). This study aimed to assess the prevalence of ERCP-related complications, their common risk factors, and specifically the role of difficulty of the procedure based on ASGE grading.

Material and Methods:
This cross-sectional study was performed on 620 ERCP-operated patients over 4 years in two tertiary referral centers affiliated with Isfahan University of Medical Sciences. Data about the difficulty of procedures based on the ASGE grading scale, complications including pancreatitis, bleeding, infection, perforation, arrhythmia, respiratory suppression, aspiration, and major common risk factors were collected.

Results:
The overall prevalence of complications was 11.6% including pancreatitis 8.2%, perforation 0.8%, gastrointestinal bleeding 1.3%, cholangitis 2.4%, and cardiopulmonary problems 0.5% (arrhythmia 0.3% and respiratory depression 0.2%). Patients with pancreatic contrast injection (66.7% vs. 11.3% P = 0.04) and sphincter of Oddi dysfunction (SOD) (44.4% vs. 11.1%; P = 0.01) showed a statistically significant higher overall complication rate. The association of these risk factors remained significant in multivariable logistic regression analysis. Patients with pancreatic contrast injection also showed a statistically significant higher prevalence of post-ERCP pancreatitis (66.7% vs. 11.3% P = 0.04). Furthermore, a significantly higher prevalence of arrhythmia (3.6% vs. 0; P = 0.008) was observed among patients with difficult cannulation. Based on the ASGE difficulty grading score, most of the patients were classified as grade 2 (74.2%) and 3 and 4 (23.4%). No statistically significant difference was noted between the difficulty-based groups in terms of complications.

Conclusion:
The current study showed that the most critical risk factors of ERCP-induced complications were pancreatic contrast injection and SOD. ASGE grading scale for ERCP complexity did not predict the occurrence of complications in our study population.
Variations of Nutcracker Phenomenon
Authors: Nautiyal Anisha , Sharma Deepika , Sharan Anjali , Kumar Piyush , Saxena Swati , Maurya Rajesh , Maheshwari Sonam , Agarwal Jolly , Pant M. K 
Published: February 2023

Introduction:
The nutcracker phenomenon (NCP) (or the left renal vein [LRV] entrapment) focuses on the constriction of the LRV. It occurs commonly between the abdominal aorta (AA) and the superior mesenteric artery. The resulting clinical manifestation of this phenomenon is known as the nutcracker syndrome (NCS). Three types of this phenomenon have been reported: anterior, posterior, and mixed. NCP is a rare finding as reported by various authors. The aim of this study is to know the prevalence of NCP in the population of Uttarakhand, India.

Methodology:
The study was conducted to understand the tributaries of the renal veins and any variations in their pattern via 160-slice computed tomography (CT) angiography. CT angiographies were retrospectively studied to study the renal vasculature. A total of 14 renal veins which included four accessory renal veins (aRVs) (one left and three right) were analyzed from cadaveric dissection and 44 CT films were included (36 males and eight females) with 98 renal veins which included 10 aRVs (three left and seven right).

Results:
The current study was done on 49 cases (five cadavers and 44 CT angiography), in which a 10.2% prevalence of NCP was recorded. All were variants of mixed types of NCP.

Conclusion:
Although the NCP and NCS are rare occurrences, it has been determined that it was possibly underdiagnosed due to a lack of the proper advanced imaging and diagnostic modalities. Hence, it led to the undertreatment of the same. With recent development in diagnostic modalities such as multidetector CT, CT angiography, magnetic resonance angiography, etc., there has been a rise in diagnosis of NCP and NCS, thus resulting in increased prevalence.
Variations of Branching Pattern of the Dorsalis Pedis Artery
Authors: Patel Dinesh K. , Shinde Amol Ashok 
Published: February 2023

Background:
Dorsalis pedis artery (DPA) is the chief artery of foot. It provides nutrition to the dorsum of the foot. Palpation of DPA is essential for the diagnosis of peripheral vascular diseases. Cutaneous flaps supplied by branches of DPA are used in various reconstruction surgeries.

Methodology:
50 meticulously dissected lower limbs of both sides and known sex were observed for morphometry, asymmetry and sexual dimorphism of DPA and its branches. Variations like absent arcuate artery and extra lateral tarsal arteries were looked for.

Results:
Absent arcuate artery was seen in 12%. Three tarsal metatarsal arteries and two tarsal metatarsal arteries were seen in 4% and 16%, respectively. An extremely rare case of U-shaped loop joining two tarsal metatarsal arteries was seen in two limbs.

Conclusion:
Rare variations like multiple tarsal arteries joined by U-shaped loop and absent arcuate artery seen in our study are of importance for reconstruction surgeries using DPA flaps.
Anterior scleral thickness in patients of central serous chorioretinopathy
Authors: Mohapatra Tanmay , Trehan Hemant Singh , Kurumkattil Raji , Gupta Radhika , Yadav Yogesh , Singh Prakhar Kumar 
Published: February 2023

BACKGROUND:
The aim of this study was to determine whether anterior scleral thickness (AST) varies significantly between patients with central serous chorioretinopathy (CSCR) versus normal individuals. To validate scleral thickness measurements by ultrasound biomicroscopy (UBM) vis a vis anterior segment optical coherence tomography (ASOCT).

METHODS:
This case–control study analyzed 50 eyes of 50 patients with CSCR (cases) and compared it with that of 50 eyes of 50 age- and gender-matched controls. In cases, AST was measured at 1 mm and 2 mm temporal to the temporal scleral spur by ASOCT and UBM. In controls, AST was measured only by ASOCT. In all participants, posterior choroidal thickness (CT) was measured subfoveally, 1 mm nasal and 1 mm temporal to fovea by enhanced depth imaging optical coherence tomography.

RESULTS:
The mean AST, as measured by ASOCT among cases and controls was 703.86 μm and 667.54 μm, respectively (P = 0.006). The mean AST by ASOCT and UBM in cases were 703.86 μm and 657.42 μm, respectively (P = 0.001). AST measurement by ASOCT and UBM showed a positive and statistically significant correlation (r = 0.431, P = 0.000). The mean CT among cases and controls was 443.56 μm and 373.88 μm, respectively (P = 0.000). We found a weak positive correlation (r = 0.11) in cases and weaker positive correlation in controls, between CT and AST measured by ASOCT.

CONCLUSIONS:
Our findings suggest that AST varies significantly between patients with CSCR versus normal individuals. We found poor agreement of AST when measured by ASOCT and UBM.
Orthogonal variable spreading factor encoded unmanned aerial vehicle‐assisted nonorthogonal multiple access system with hybrid physical layer security
Authors: Omor Faruk Md. , Jafor Sadique Joarder , Cumanan Kanapathippillai , Enayet Ullah Shaikh 
Published: February 2023

AbstractPhysical layer security (PLS) can improve the security of both terrestrial and nonterrestrial wireless communication networks. This study proposes a simplified framework for nonterrestrial cyclic prefixed orthogonal variable spreading factor (OVSF)‐encoded multiple‐input and multiple‐output nonorthogonal multiple access (NOMA) systems to ensure complete network security. Various useful methods are implemented, where both improved sine map and multiple parameter‐weighted‐type fractional Fourier transform encryption schemes are combined to investigate the effects of hybrid PLS. In addition, OVSF coding with power domain NOMA for multi‐user interference reduction and peak‐to‐average power ratio (PAPR) reduction is introduced. The performance of
‐rated convolutional, turbo, and repeat and accumulate channel coding with regularized zero‐forcing signal detection for forward error correction and improved bit error rate (BER) are also investigated. Simulation results ratify the pertinence of the proposed system in terms of PLS and BER performance improvement with reasonable PAPR.
PEMIKIRAN PENDIDIKAN ISLAM MENURUT BUYA HAMKA
Authors: Mursal Mursal 
Published: February 2023

Pendidikan Islam mempunyai beberapa permasalahan yang perlu di diskusikan konsepnya diantaranya tentang tujuan, materi, metode, pendidik anak didik dan evaluasi dimana dengan konstruksi dan konsepsi yang baik akan berdampak kepada kualitas pendidikan Islam Itu sendiri oleh kerenanya pemikir pemikir Islam berupaya merekonstruksi konsep pendidikan Islam tersebut agar pendidikan Islam bisa berdaptasi dan mengikuti perkembangan zaman. Dalam artikel ini penulis berupaya menguraikan konsep pendidikan Islam yang ditawarkan Buya Hamka dimana beliu merupakan tokoh dalam berbagai disiplin ilmu diantaranya di bidang Tafsir, Pendidikan Ahlak, Politik, Sosial dan lain lain. Namun dalam artikel ini penulis hanya memfokuskan dalam bidang pendidikan Islam
Adult Literacy in Central Queensland
Authors: Harreveld Bobby 
Published: February 2023

The sociocultural markers of adult literacy teachers'. identities are significant for understanding the nature of teaching which is constructed through, and contingent upon, diverse geographical and systemic spaces - at once a dilemma and a strategy inpromoting education in regional areas. This article reports on one aspect of the work of a cohort of 23 adult literacy teachers living in regional, rural and remote areas of Central Queensland. Discourse theory is used to frame the conceptualisation of one particular teacher's discursive positioning of her work. The article concludes that the relationships between adults positioned as teachers and students can become a community resource with the potential for rural engagement and for transformation of social and economic capital in such communities.
Памфлет жанрининг таснифланиши ва турлари
Authors: Хусниддинова Гульшода , Aззамов Юсуфжон 
Published: February 2023

Ушбу ишнинг мақсади памфлет жанрининг ёзилиш услубига кўра турларини ўрганишдан иборат. Унинг пайдо бўлиши, маъно-моҳияти, мақсади, хусусиятлари, ўзига хос жиҳатлари, ёзилиш услубига кўра турлари билан боғлиқ мулоҳазалар ва шу турда ёзилган асарлар ҳақидаги маълумотлар борасида фикр юритдик. Памфлет жанрини ўрганишда йўл қўйилган камчиликларга тўхталдик ва уларни тўлдиришга ҳаракат қилдик. Жанрни фельетон жанрига таққослаган ҳолда ўргандик. Унда ёзилган асарлар таҳлилини кузатиш асносида маълум гуруҳларга ва бу гуруҳларни ҳам ўз ўрнида турларга ажратдик. Ҳар бир турга мансуб мақолалар, асарларни келтириб, уларга изоҳ бердик. Памфлет жанрининг адабий танқидчиликда тутган ўрни, унинг мақсади ва вазифалари, журналистикадаги аҳамияти, кўлами ва услуби ҳақида фикр юритдик.
Maktabgacha yoshdagi bolalarda kreativ faollikni rivojlantirishda o‘yinning roli
Authors: Nuraddinova Raviyajan 
Published: February 2023

Mazkur maqolada kreativlik tushunchasi haqidagi qarashlar, maktabgacha yoshdagi bolalarda kreativ faollikni rivojlantirishda o‘yinning roli va kompetensiyaviy yondashuv asosida rivojlantirish imkoniyatlari tahliliy va qiyosiy bayon etildi. Unda maktabgacha yoshdagi bolalarning o‘yinga bo‘lgan munosabati va o‘yin asosida faollikni rivojlantirish o‘rganilgan.
Chinese Research Progress Of Blood Eosinophils As Biomarkers In Chronic Obstructive Pulmonary Disease
Authors: Ying Li , Rongjuan Zhuang ,Shuliang Guo  
Published: February 2023

Chronic obstructive pulmonary disease (COPD) is a common chronic airway inflammatory disease. With its heterogeneity in clinical manifestations, treatment responses and prognosis, biomarkers that can predict treatment benefits and risk stratification of deterioration are very important. In recent years, many studies have reported that eosinophils are highly involved in the development of airway inflammation in COPD. The baseline blood eosinophil count(EOS) is related to the therapeutic effect of inhaled corticosteroids(ICS) and the risk of acute exacerbation in patients. The level of EOS may be affected by many factors such as geography, race, etc. In domestic clinical work, the actual reference data of EOS may not be consistent with the recommended reference threshold value in GOLD. Since there is no uniform and accurate epidemiological data on EOS in COPD patients in China, this review focuses on the research progress and controversy in the areas of EOS and COPD airway inflammation, development as biomarkers, and the role of guiding the clinical application of ICS, to discuss the setting of the critical value of EOS of Chinese COPD patients.
ULTIMUM REMEDIUM DALAM HUKUM PIDANA PAJAK: TEORI DAN PRAKTIK
Authors: Yumanto Bina , Hutauruk Paruhum Aurora Sotarduga 
Published: February 2023

The objective of Legal study is for answering questions on what and how it should be as das sollen. However, legal studies are not solely researching validity of rules as das sollen, but also researching whether a legal rule be in force or not, about what should be done or should tend to be prescriptive (Sudikno Mertokusumo, 2011). Therefore, legal research aside from having dogmatic and systematic characters, also should also apprehend asymmetry between das sollen and das sein. This paper essay is researching criminal tax law in General Provision and Procedures Law (UU KUP), as spring of ius positum and it’s legitimate systematic within tax law as well as other law within Indonesia’s legal system. From juridical normative research, there are few conclusions about ambiguity and asymmetry between fundamental principles and their pronounced legal regulations. As well about the absence of a strict (criminal) procedures law as rule of adjudication for application of criminal tax law, provoke ambiguity in operation and how to manifest criminal tax law as das sein. From this vantage point, this research stretched in accordance with criminal tax law effectiveness as a tool to obtain society welfare and harborage.
INTRA-CRANIAL HEMATOMAS SECONDARY OF HEAD INJURIES SEEN AT CHU PZAGA OF MAHAJANGA
Authors: M Ramarokoto , WF Rakotodranibe , J S Bemora , W Ratovondrainy , M Rabarijaona , C Andriamamonjy 
Published: February 2023

Head trauma regroups every post-traumatic lesions surgical or not concerning the skul l, its envelopes and its contents especially. The aim of the study was to determine the epidemi ological, clinical and treatment profile of intra-cranial post traumatic hematoma at neurosurgi cal unit of PZaGa University Teaching Hospital. It is a retrospective, descriptive study about head injury with intra-cranial hematoma a dmitted and managed at the neurosurgical unit from December 2017 to July 2018. We had 244 cases of head trauma among 325 hospitalized patients with 34 cases of int ra-cranial hematoma (13, 93%). Patients with head trauma were young adults, with male pred ominance, living in Mahajanga town. The main risk factor found was alcoholic intoxication (52,94%). It was about benign head trauma (79, 41%), among main signs found was agitation.Brain CT Scan was used in 82,35% of cases. Surgical indication was almost confirmed by C T Scan but for the 17, 65% of cases, diagnosis was confirmed per-operatively. Main lesions o bserved were EDH (42, 86%) and chronic SDH (21,43%). Their management was early. Med ical treatment was sufficient in 20,59% of patients and 79,41% had surgical intervention. Evo lution was favorable but we had 2,94% deaths.Information, communication and education of a very socio professional stratus should be done.
INTRODUCTION DU SULFATE DE MAGNESIUM DANS LA PRISE EN CHARGE DE LA PREECLAMPSIE SEVERE AU CHUGOB
Authors: Razafindrainibe T , S Rakotonomenjanahary  , Raelison JG , Rahanitriniaina NMP , Andrianirina M , MS Razafindrabe  , Rajaonera AT 
Published: February 2023

Introduction: Preeclampsia is a major cause of maternal and newborn morbi-mortality mostly through eclampsia and its complications. Magnesium sulphate is now approved to prevent eclamptic seizures. Our survey is aimed at showing the benefits and risks of its use in the management of severe preeclampsia.
Methods: A prospective and descriptive study was led for nine months from April to December 2016 at CHUGOB about 90 severe preeclamptic women up to 28 weeks of gestation with imminent eclampsia and/or decision of delivery (or in labor); treated by magnesium sulphate before, during and/or after delivery.
Results: The prevalence of this pathology was 1, 9%. It occurred before 37 weeks of gestation in 62, 22% of the cases, with middle age of 28, 89 years old. Systolic arterial blood pressure was greater than 160 mmHg (92, 22%), accompanied by significant proteinuria (61, 11%), and clinical signs of imminent eclampsia (65, 56%). Fifty five of them (61, 11%) needed antihypertensive therapy. The mainly side effects were minor (feeling of warmth in 54, 44%). There were six overdoses which regressed when treatment was stopped and calcium gluconate administered. No patients had eclampsia nor death. The newborn morbi-mortality hadn’t been affected.
Conclusion: Magnesium sulphate is effective especially in imminent eclampsia. The benefits from its use were above the risks for the mother and her baby with rigorous clinic follow up.
We recommend it.