bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of the clinical efficacy and prognosis of the two techniques for treating partial articular-sided supraspinatus tendon tears under arthroscopy
Authors: Zhang Li , Fang Zhanglu , Zhang Yin , Wang Xun , Hong Zheping 
Published: May 2023

Abstract
Background: At present, shoulder arthroscopy is usually used for treatment of rotator cuff injuries.
Objective: To compare the clinical efficacy of the arthroscopic transtendon repair method and the arthroscopic full-thickness repair method in the treatment of patients with Ellman III partial articular-sided supraspinatus tendon tears and to analyze the influencing factors of postoperative efficacy.
Study Design: Cohort study; level of evidence,4
Methods: A total of 84 partial-thickness rotator cuff tear (PTRCT) patients with Ellman III injuries who underwent surgical treatment in our hospital between January 2017 and January 2020 were selected and divided into the arthroscopic trans-tenon repair group (32 cases) and the arthroscopic full-thickness repair group (54 cases). Shoulder joint pain and functional status were assessed by the Constant score, ASES score and VAS score; shoulder mobility was assessed by measuring shoulder ROM. The clinical outcomes of the two groups of patients were compared, and the factors affecting the postoperative efficacy of the patients were investigated.
Results: All patients were followed up for at least 2 years. The Constant score, ASES score, and VAS score of the two groups of patients were all improved compared with those before surgery, and the differences were statistically significant (P<0.05). There were no significant differences in the Constant score, ASES score, or VAS score between the two groups (P>0.05). The results of binary logistic regression analysis showed that the preoperative ASES score and whether biceps tenotomy was performed were independent risk factors for satisfactory postoperative efficacy (P<0.05).
Conclusion: For patients with Ellman III partial articular-sided supraspinatus tendon tears, the arthroscopic transtendon repair method and the arthroscopic full-thickness repair method can both significantly improve the shoulder pain and function of the patient, but there is no significant difference between the efficacy of the two surgical methods. Surgeons can choose the appropriate surgical method according to his own habits and skill level. The preoperative ASES score and whether biceps tenotomy was performed were independent risk factors for satisfactory postoperative efficacy in PTRCT patients with Ellman III injury.
“Multiple-Choice Items should be sequenced in order of difficulty with the easiest ones placed first”. Does it really affect performance?
Authors: Gyamfi Abraham , Acquaye Rosemary , Adjei Charles 
Published: May 2023

Abstract
The purpose of the study was to find out if order of arrangement of multiple-choice test items significantly affects students’ performance. The study made use of a descriptive research design. The target population for the study was all education students of Valley View University, Ghana from the Oyibi, Takoradi and Kumasi study Centres. The accessible population for the study was all Sandwich education students of Valley View University who registered for the Measurement and Evaluation course for the 2022/2023 academic year and sat for the end of semester examination at Oyibi study centre. The census procedure was used to select the sample for the study. Five sets of 25 multiple-choice test items in Measurement and Evaluation were administered to the 183 students as their end of semester examination. Data was analyzed using descriptive statistics and three-way ANOVA. The results indicated that order of arrangement of multiple-choice test items has no effect on performance and that the order of arrangement of multiple-choice test items has no effect on performance due to gender and study centre. It therefore recommended that using varying order of arrangement of multiple-choice items should be encouraged as a way of checking examination malpractice.
Wild Mushroom (Daedalea sp) as Biosource for Silver Nanoparticles: From Synthesis to Enhance antimicrobial, Biomedical &amp; Environmental Applications
Authors: kamal Asif , Ahmad Shabir , wahab Abdul , Okla Mohammad K. , Saleh Ibrahim A. 
Published: May 2023

Abstract
The current study presents novel, green, and mycosynthesized silver nanoparticles (NPs) for various biomedical and environmental applications, using the biosource Daedalea sp. In the study, AgNO3 was converted into stable elemental silver (Ag0) at a nanometric scale using a aqueous extract of Daedalea sp mushroom. The NPs were extremely pure and stable, with an average size of 24.3 nm and an irregular morphology. A wide range of biomedical applications, such as bactericidal, fungicidal, leishmaniasis, antioxidant, anti-diabetic, and biocompatibility studies, made use of the characterized nanoparticles. Our research revealed that MDR bacterial strains and spore-forming fungal strains were both highly responsive to Daedalea sp mediated AgNPs. All of the tested UTI bacterial isolates were resistant to non-coated antibiotics, but by adding 1% of the synthesized AgNPs, the antibiotics' bactericidal potential was greatly increased. The NPs also demonstrated dose-dependent cytotoxic activity against Leishmania Tropica, with significant LC50 values for promastigote and amastigote parasites of 248 and 251 g/mL, respectively. Additionally, significant inhibition of -amylase, -glucosidase, acetylcholinesterase (AChE), and butrylcholineterase (BChE) were noted, suggesting possible disease and anti-diabetic effects. Additionally, the particles' remarkable biocompatibility with human red blood cells was discovered. The photocatalytic activity of mycosynthesized AgNPs resulted in 98.2% degradation of indigo carmine dye in 140 minutes. Daedalea sp AgNPs can be used as novel candidates for a variety of biomedical and environmental applications due to their eco-friendly synthesis, biosafe nature, and excellent physicochemical properties.
Anti-nephrin antibodies in idiopathic nephrotic syndrome in Japanese children
Authors: Horinouchi Tomoko , Watts Andrew J B , Nagano China , Ichikawa Yuta , Tanaka Yu , Kitakado Hideaki , Ueda Chika , Nagai Sadayuki , Kondo Atsushi , Sakakibara Nana , Fujimura Junya , Kamiyoshi Naohiro , Ishimori Shingo , Kaito Hiroshi , Shima Yuko , Nozu Kandai , Sampson Matthew G , Weins Astrid , Iijima Kazumoto 
Published: May 2023

Abstract
Background
Many patients with childhood idiopathic nephrotic syndrome are steroid-sensitive. Several genome-wide association studies have suggested a polygenic contribution, particularly in the HLA DR/DQ region and a locus including nephrin, but the etiology remains unclear. Anti-nephrin antibodies have recently been reported in both adults and children with biopsy proven minimal change disease (MCD), but the presence of anti-nephrin antibodies in Japanese childhood idiopathic nephrotic syndrome (INS) has not been investigated.
Methods
Anti-nephrin antibodies were measured by ELISA in paired plasma samples obtained from 14 Japanese pediatric patients with INS (male/female: 8/6), at onset (active disease) and following steroid monotherapy.
Results
The median age at the onset was 75.5 months (interquartile range (IQR): 45-113). Steroid sensitivity resulted in complete remission in 13 patients and almost complete remission in one patient after 4 weeks of glucocorticoid monotherapy. Circulating anti-nephrin antibodies were detected in seven of 14 patients during active disease. In all cases, anti-nephrin antibodies were significantly reduced following treatment concordant with clinical response. There were no differences between the positive and negative groups in pre-treatment parameters. Of the 13 patients who achieved complete remission, nine had at least one relapse during a median follow-up of 851 days (IQR: 808-973). There was also no significant difference in the relapse-free period after the onset between the two groups (P=0.658).
Conclusions
We identified circulating anti-nephrin antibodies in half of Japanese pediatric patients with INS at initial presentation, which is higher than has been previously reported in a North American cohort.
Prevalence and factors associated with depression and anxiety among COVID-19 survivors in Dhaka city
Authors: Kibria Md. Golam , Rahman Ummay Salma , Islam Taslima , Amin S M Sayadat , Rahman Md. Mahbubur , Ahmed Shakil 
Published: May 2023

Abstract
Background Coronavirus disease 2019 (COVID-19) is a global public health concern. Evidence shows that depression and anxiety are common among patients with COVID-19 after recovery. About one-third of the total COVID-19 cases in Bangladesh have been reported in Dhaka city. Therefore, the study aimed to assess the prevalence of depression and anxiety and associated factors among COVID-19 survivors in Dhaka city.Methods A cross-sectional study was conducted among a total of 384 COVID-19 survivors aged 18 years or older. Data collection was done through face-to-face and telephone interviews using a semi-structured questionnaire. Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder (GAD-7) scales were used to assess depression and anxiety, respectively. Binary logistic regression analysis was performed to identify factors associated with depression and anxiety.Results The overall prevalence of depression and anxiety was 26.0% and 23.2%, respectively. Respondents aged ≥ 60 years were 2.85 and 3.59 times more likely to have depression and anxiety, respectively than those aged 18–39 years. Hospitalized COVID-19 patients had a 1.98 and 2.28 times higher chance of having depression and anxiety, respectively than non-hospitalized COVID-19 patients. COVID-19 patients with comorbidities were at a 3.48 and 2.87 times higher risk of depression and anxiety, respectively compared to those without comorbidities.Conclusions The study reported a high prevalence of depression and anxiety among COVID-19 survivors in Dhaka city. The findings suggest the need for appropriate interventions to reduce mental health complications in COVID-19 survivors.
Persistence of heavy metals and human health risk assessment in the South Indian industrial area
Authors: Arunakumari Kondarathi , Begum Farveen , Surinaidu Lagudu , Nandan Mogali Jayaraja , Alapati Umamaheswari 
Published: May 2023

Abstract
The present study provided a comprehensive evaluation of heavy metal contamination from soil to groundwater and the associated risk to human health in an industrial area situated in Telangana state, South India. Soils at three depth levels (0, 20, and 80 cm) and groundwater samples at 32 locations have been collected in the area. The samples have been analyzed for trace metals (Mn, B, Zn, Cr, Pb, Ni, Hg, Cd, and As) to understand the heavy metal contamination. Furthermore, geo-accumulation (Igeo) of heavy metals, contamination factor, pollution index, and human health risks due to prolonged exposure to contaminated water are estimated. The results indicated that soils are moderately contaminated at 18.5, 25.9, 7.4, 14.8, and 7.1% of locations by B, Zn, Cr, Pb, Ni, and Cd, respectively, as per Igeo at 80-cm depth. However, the contamination factor indicated that 14.8% of the locations were contaminated by Mn and Zn and 7.4, 70.3, 66.6, 74, and 3.7% by B, Cr, Pb, Ni, and Cd, respectively. However, groundwater is only contaminated when levels are less than 3 m below ground level. The results also indicated higher carcinogenetic health risks if groundwater is used for a longer time.
Estimating the energy dissipation of flow passing over triangular and trapezoidal plan weirs using the GMDH model
Authors: Parsaie Abbas , Dehdar-Behbahani Sadegh , Chadee Aaron Anil , Haghiabi Amir Hamzeh 
Published: May 2023

Abstract
Weirs are one of the most common hydraulic structures used in water engineering projects. In this research, a group method of data handling (GMDH) was developed to estimate the energy dissipation of the flow passing over the labyrinth weirs with triangular and trapezoidal plans. To compare the performance of this model with other types of soft computing models, a multilayer perceptron neural network (MLPNN) was developed. The dimensionless parameters derived from dimensional analysis, including the relative upstream head (ho/P), the number of cycles (Ncy), the Froude number ( Fr), and the magnification ratio (Mr) were used as input variables. The error statistical indicators of the GMDH model in the training phase were R2 = 0.913, RMSE = 0.010, and in the testing phase were R2 = 0.829, RMSE = 0.015. The error statistical indicators of the MLPNN in the training phase were R2 = 0.957, RMSE = 0.007, and in the testing phase were R2 = 0.945, RMSE = 0.009. Examining the structure of the GMDH network shows that ho/P, Ncy, and Mr play more meaningful roles in the development network.
Evaluation of Lemna minor phytoremediation performance for the treatment of dairy wastewater
Authors: Sahi Wassila , Megateli Smain 
Published: May 2023

Abstract

The aim of the study was to evaluate the efficiency of Lemna minor to purify synthetic dairy wastewater (SDW) and real dairy wastewater (RDW), both diluted and undiluted. Results showed that Lemna significantly reduced electrical conductivity (EC); the removal efficiency for EC was 19.4% in RDW and 9.8% in SDW. Higher values were recorded for diluted real dairy wastewater (DRDW) (41%) and for diluted synthetic dairy wastewater (DSDW) (35.8%). Total suspended solids were slightly reduced in RDW (14%) and SDW (13.5%), compared to DSDW (25%) and DRDW (29%). Greater removing efficiency of chemical oxygen demand was recorded in DRDW (60%) and DSDW (55.5%) compared to RDW (27.6%) and SDW (27%). In RDW, nitrogen and phosphorus removal were 24.8 and 37.4% and in SDW were 25 and 48.6%, respectively, compared to much higher results in diluted effluents, and nitrogen removal was 65.4% in DRDW and 63.5% in DSDW, but the best results were recorded for phosphorus removal in DSDW (78.8%) and DRDW (87%). The higher elimination of all the parameters investigated in the units populated with duckweed compared to the control attests to the effectiveness of L. minor in the phytoremediation of dairy wastewater, especially when reducing the primary pollutant load.
PERFIL CLÍNICO-EPIDEMIOLÓGICO DE PACIENTES PEDIÁTRICOS DE UM CENTRO DE ONCOHEMATOLOGIA DE PERNAMBUCO
Authors: Laiza Candido da Silva Gabriela , Carlos Rodrigues de Almeida Híttalo , Fonseca da Silveira Márcia Maria , Veras Sobral Ana Paula 
Published: May 2023

Introdução: O câncer infantojuvenil corresponde a um grupo de várias doenças que têm em comum a proliferação descontrolada de células anormais e que pode ocorrer em qualquer local do organismo. As neoplasias que acometem crianças e adolescentes devem ser estudadas separadamente, pois estas diferem dos tumores que acometem os adultos. Objetivo: Identificar os tipos de neoplasias mais frequentes na infância e adolescência e analisar o perfil clínico-epidemiológico dos pacientes. Metodologia: Estudo de transversal exploratório, de natureza aplicada com análise documental, realizado no Centro de Oncohematologia Pediátrica do Hospital Universitário Oswaldo Cruz (CEONHPE-HUOC). Foram incluídos crianças e adolescentes diagnosticados com neoplasia e tratados por terapia antineoplásica. Os critérios de exclusão foram crianças e adolescentes normorreativas e/ou com doenças sistêmicas; prontuários ilegíveis ou com falta de informações clínicas. Resultados: Identificou-se que 54,21% dos pacientes eram do sexo feminino, seguido por 44,86% do sexo masculino e apenas 0,93% não responderam ou não tiveram o sexo identificado. A faixa etária prevalente no estudo foi o de crianças de 5 a 14 anos (54,21%), ainda sobre o perfil dos pacientes, identificou-se que população autodeclarada como negra foi a mais prevalente representando 44,86% do total, seguido dos brancos com 43,93%. O diagnóstico que prevaleceu foi o de Leucemia Linfoide Aguda (LLA) (23,36%), seguido pela Retinoblastoma (7,48%) e pela Rabdomiossarcoma embrionário (6,54%), e consequentemente o local da neoplasia primária que prevaleceu foi a Medula óssea (27,10%) seguido do olho (10,28%), deste total nota-se que o tratamento antineoplásico mais utilizado foi a quimioterapia (40,19%) seguido da quimioterapia associada à radioterapia (12,15%) e pela quimioterapia associada a cirurgia (10,28%). Conclusões: A leucemia linfoide aguda foi a neoplasia mais frequente na infância e adolescência, com prevalência na idade entre 5 e 14 anos, no sexo feminino e na etnia negra. A terapia antineoplásica mais utilizada foi a quimioterapia, seguida da associação entre quimioterapia e radioterapia.
CARACTERÍSTICAS DEMOGRÁFICAS, SOCIOECONÔMICAS E DA PROCURA DOS USUÁRIOS EM UM SERVIÇO DE REABILITAÇÃO FÍSICA DE REFERÊNCIA ESTADUAL, MATO GROSSO, 2021
Authors: Lima Adriana Maria Silva , Guimarães Lenir Vaz , Martinelli Nereide Lúcia , Oliveira Junior Gilmar Jorge de 
Published: May 2023

Introdução: O estudo dos fatores sociodemográficos e socioeconômicos de usuários que demandam o Sistema Único de Saúde oportuniza o conhecimento das suas características sendo importantes para o planejamento e a avaliação das ações dos serviços de saúde procurados por esta população. Objetivo: Descrever as características demográficas, socioeconômicas e da procura dos usuários adultos de um serviço de reabilitação física de um Centro Especializado em Reabilitação de referência no estado de Mato Grosso. Metodologia: Estudo observacional descritivo baseado nos dados dos prontuários de usuários atendidos no setor de acolhimento de um Centro Especializado em Reabilitação localizado em Cuiabá, Mato Grosso, no período de fevereiro a maio de 2021. Foram analisados os dados demográficos e socioeconômicos de usuários adultos de ambos os sexos. Utilizou-se o teste de qui-quadrado de Pearson para as associações entre as variáveis segundo eixo de reabilitação (ortopédica e neurológica). O projeto de pesquisa foi aprovado pelo Comitê de Ética em Pesquisa. Resultados: Foram analisados 196 prontuários dos quais 69% procuraram por reabilitação ortopédica e 31% por reabilitação neurológica. Observaram-se diferenças estatisticamente significantes entre as frequências dos dois eixos de reabilitação física estudados nas variáveis idade (p=0,0005), escolaridade (p=0,0031), principal atividade de trabalho (p=0,0045), doenças concomitantes (p=0,0016), tratamento em outro estabelecimento de saúde (p=0,0041) e motivo da procura pela reabilitação (p<0,0001). Conclusões: Os resultados mostraram que existem diferenças entre as características demográficas, socioeconômicas e da procura pelo serviço entre usuários com demanda de reabilitação ortopédica e neurológica sugerindo que as necessidades de saúde e de reabilitação dependem da singularidade dos casos. Recomenda-se que os serviços de reabilitação fortaleçam suas articulações com a atenção primária, com o sistema educacional e com ações de qualificação profissional voltados às pessoas com deficiência.
Palavras-Chave: Acesso aos Serviços de Saúde; Centros de Reabilitação; Pessoas com Deficiência; Indicadores Básicos de Saúde; Avaliação em Saúde.
Recent Discovery of Peptidomimetics for the Treatment of Coronavirus
(COVID-19), Human Coronavirus, and Enteroviruses
Authors: De Surya K. 
Published: May 2023

Abstract:
This patent describes the synthesis of compounds, methods, and compositions
for preventing, treating, and/or curing Covid-19, human coronavirus, and enterovirus infections.
Some peptidomimetic compounds are very potent and could be a game changer
in new treatment therapy for COVID-19.
A Comprehensive Review on Trigonella foenum-graecum L. with Special
Reference to Unani Medicine
Authors: Khatoon Faiza , Azahar Mohd , Uddin Qamar , Husain Nazim , Moin Md Sanaul , Khan Shayni 
Published: May 2023

Abstract:
Trigonella foenum-graecum L., commonly known as Ḥulba or Methi in Unani medicine,
is an annual self-pollinating plant belonging to the Leguminosae family. It has been utilized for
centuries to treat a wide range of diseases, and modern research has supported its traditional medicinal
claims. In this study, the authors have conducted manual and online searches to gather and summarize
the scientific literature on Ḥulba. This article seeks to underscore the potential of Ḥulba in addressing
a variety of health conditions as identified by esteemed classical Unani scholars, as well as to
investigate its phytochemistry and pharmacological properties in contemporary medicine. The authors
have utilized electronic databases, such as PubMed, Science Direct, DOAJ, Google Scholar, and
Ayush Research Portal to filter published material. According to the gathered literature, Unani physicians
have consistently recommended Ḥulba seeds for a variety of ailments, such as indigestion, flatulence,
colitis, arthritis, backache, paralysis, headaches, common cold, cough, bronchial asthma, diabetes
mellitus, vitiligo, and pityriasis. Additionally, the seeds and green leaves of Ḥulba contain several
chemical constituents, such as alkaloids, flavonoids, steroids, saponins, and amino acids. Furthermore,
several pharmacological studies have demonstrated that Ḥulba possesses various properties, including
antidiabetic, antispasmodic, hypolipidemic, immunological, antibacterial, anthelmintic, antiinflammatory,
analgesic, and antioxidant activities. Based on the available evidence, it can be concluded
that Ḥulba has been effectively used in Unani medicine for treating a wide range of diseases.
Unani scholars have extensively documented its pharmacological properties, which have been supported
by modern research studies. However, further research is necessary to validate some of the
claims made in traditional medicine using scientific parameters.