bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prediction of cognitive decline in Parkinson’s disease (PD) patients with electroencephalography (EEG) connectivity characterized by time-between-phase-crossing (TBPC)
Authors: Gschwandtner Ute , Bogaarts Guy , Roth Volker , Fuhr Peter 
Published: March 2023

AbstractThe aim of the study is to identify the dynamic change pattern of EEG to predict cognitive decline in patients with Parkinson’s disease. Here we demonstrate that the quantification of synchrony-pattern changes across the scalp, measured using electroencephalography (EEG), offers an alternative approach of observing an individual’s functional brain organization. This method, called “Time-Between-Phase-Crossing” (TBPC), is based on the same phenomenon as the phase-lag-index (PLI); it also considers intermittent changes in the signals of phase differences between pairs of EEG signals, but additionally analyzes dynamic connectivity changes. We used data from 75 non-demented Parkinson’s disease patients and 72 healthy controls, who were followed over a period of 3 years. Statistics were calculated using connectome-based modeling (CPM) and receiver operating characteristic (ROC). We show that TBPC profiles, via the use of intermittent changes in signals of analytic phase differences of pairs of EEG signals, can be used to predict cognitive decline in Parkinson’s disease (p < 0.05).
Facile synthesis of novel NNO-tethered copper(ii) complexes: characterization details, theoretical studies, promising enzyme-like activities, and biomolecular interactions
Authors: Mandal Subrata , Naskar Rahul , Mondal Apurba Sau , Bera Biswajit , Mondal Tapan K. 
Published: March 2023

This research work reports the synthesis, X-ray structure, bio and catalytic activities of three mononuclear copper(II) complexes [Cu(L)X] with salicylaldimine Schiff base (LH), where X denotes NCS, N3 and NO3 for complex 1, 2 and 3 respectively.
Mechanical stability ofcis,trans-poly(p-phenylene vinylenes)
Authors: Janpatompong Yurachat , Suwada Kamil , Turner Michael L. , De Bo Guillaume 
Published: March 2023

The performance of flexible electronic devices must be stable to repeated mechanical deformation in use. We show that the structural and optical properties of cis, trans-PPVs are maintained when subjected to elongational forces during ultrasonication.
How animal models can be utilized to find new biomarkers for cardiovascular diseases
Authors: Shimosawa Tatsuo 
Published: March 2023

Abstract
It has been more than 60 years since the colonized genetic model of hypertension was first established. Model animals contribute greatly to the advance of understanding of the pathophysiology and development of effective therapy. In this review, the author focuses on two points: gene-related biomarkers and the use of humanized mice to search for biomarkers. First, the author provides an overview of the history of the establishment of hypertension and salt-sensitivity model rats, as well as advances in genetic analysis of causative genes of hypertension and the theory of renal causes of salt-sensitive hypertension. The recent animal model analysis adds the notion of the importance of epigenetic alterations in addition to the genetic causes of hypertension. Both germline mutations and epigenetic analysis of congenic animal models are complementary and should carry out furtherly. Among epigenetic factors, non-coding RNA is a promising new ‘liquid biopsy’ which is originally applied to diagnose cancers by detecting cancer cell-derived DNA, RNA, or other molecules in a person’s body fluid and now it can be applied to any pathophysiological conditions. Then, the author reviews the usefulness of humanized mice. Few studies have used such mice in cardiovascular research, but the present study highlights a study of immune-related disease and the search for biomarkers in such mice. Perspectives on using humanized mice in cardiovascular research are discussed.
Consensus control of semi‐Markov jump topology multiple direct‐drive motion system
Authors: Qiu Li , Yu Junjie , Monirul Islam Md , Liu Chengxiang , Wu Zongze 
Published: March 2023

AbstractRandom jump of network communication topology challenges the tracking accuracy of linear switched reluctance motor (LSRM) system. This paper studies the pilot‐following consensus control of the multiple direct‐drive motion system (MDDMS) with semi‐Markov jump topology. The mathematical model of LSRM is constructed and the multi‐phase excitation strategy is studied. The directed graph is used to model the information transmission among the leaders and follower, and a new mechanism consensus based on previous states is provided. A consensus system based on semi‐Markov jump topology is constructed and the problem of consensus is shifted into a problem of stability analysis. A sufficient condition for consensus problem is obtained by using semi‐Markov switching system theory and graph theory. The MDDMS achieves consensus in the form of exponential convergence under the designed consensus controller. Several groups of simulation results verify the effectiveness of the proposed consensus control method.
Multiple harmonic sources identification including inverter‐based distributed generations using empirical Fourier decomposition
Authors: Motlagh Shayan Z. T. , Akbari Foroud Asghar 
Published: March 2023

AbstractThis paper proposes an intelligent approach based on the empirical Fourier decomposition (EFD) to identify harmonic sources at the point of common coupling (PCC) when different inverter‐based distributed generations (DGs) like microturbine (MT), battery energy storage system (BESS), photovoltaic (PV), superconducting magnetic energy storage (SMES), wind turbine with a permanent magnet synchronous generator (PMSG), and doubly‐fed induction generator (DFIG) wind turbine are presented. In order to decrease memory storage and computational burden, strife feature selection is used. Applying just voltage signals consumes less processing time and decreases measurement devices. Moreover, the whale optimization algorithm (WOA) as the optimizer of the parameters of the support vector machine (SVM) classifier is used. Consequently, the results from the proposed method can be helpful for both engineers and researchers to plan and develop a better strategy to mitigate harmonic distortion.
Multi-wavelength spectroscopic study of shock-driven phenomena in explosive outbursts in symbiotic-like recurrent novae with an emphasis on RS Ophiuchi
Authors: Azzollini Alessandra , Shore Steven N. , Kuin Paul , Page Kim L. 
Published: March 2023

Aims. Our goal is to detail the development of RS Ophiuchi and the other Galactic symbiotic-like recurrent novae throughout their outburst and quiescence, with a particular emphasis on the propagation of the shock wave during the outburst of the binaries.
Methods. The spectral analysis has been performed using archival data according to the features of the individual datasets. Swift grism spectra were reduced and extracted using a combination of the pre-existing UVOTPY Python routine and newly written pipelines in Matlab. Other datasets were directly available in reduced form, already corrected for instrumental or background contamination, and calibrated in wavelength and flux or intensity. The work on these was done through pipelines suited for reading the data and elaborating them to extract quantities of interest for the analysis.
Results. We find striking similarities in different outbursts of the same object and for different novae. For example, RS Oph 2021 was almost identical to the 2006 outburst, despite having occurred at a different orbital phase with the observations made from a different line of sight through the red giant wind. Despite the intrinsically different properties of the binaries, striking similarities are found for different systems of the same class, for instance, the trend of the electron density over time during outburst appears to follow a general temporal development.
Toward nebular spectral modeling of magnetar-powered supernovae
Authors: Omand C. M. B. , Jerkstrand A. 
Published: March 2023

Context. Many energetic supernovae (SNe) are thought to be powered by the rotational energy of a highly magnetized, rapidly rotating neutron star. The emission from the associated luminous pulsar wind nebula (PWN) can photoionize the SN ejecta, leading to a nebular spectrum of the ejecta with signatures that might reveal the PWN. SN 2012au is hypothesized to be one such SN.
Aims. We investigate the impact of different ejecta and PWN parameters on the SN nebular spectrum, and test whether any photoionization models are consistent with SN 2012au. We study how constraints from the nebular phase can be linked into modeling of the diffusion phase and the radio emission of the magnetar.
Methods. We present a suite of late-time (1–6 yr) spectral simulations of SN ejecta powered by an inner PWN. Over a large grid of one-zone models, we study the behavior of the physical state and line emission of the SN as the PWN luminosity (LPWN), the injected spectral energy distribution (SED) temperature (TPWN), the ejecta mass (Mej), and the composition (pure O or realistic) vary. We discuss the resulting emission in the context of the observed behavior of SN 2012au, a strong candidate for a PWN-powered SN. We used optical light-curve models and broadband PWN models to predict possible radio emission from SN 2012au.
Results. The SN nebular spectrum varies as TPWN varies because the ejecta become less ionized as TPWN increases. Ejecta models with low mass and high PWN power obtain runaway ionization for O I, and in extreme cases, also O II, causing a sharp decrease in their ion fraction over a small change in the parameter space. Certain models can reproduce the oxygen line luminosities of SN 2012au reasonably well at individual epochs, but we find no model that fits over the whole time evolution. This is likely due to uncertainties and simplifications in the model setup. Using our derived constraints from the nebular phase, we predict that the magnetar powering SN 2012au had an initial rotation period ~15 ms, and it is expected to be a strong radio source (F > 100 μJy) for decades.
Dynamics of intermediate mass black holes in globular clusters
Authors: Di Cintio Pierfrancesco , Pasquato Mario , Barbieri Luca , Trani Alessandro A. , di Carlo Ugo N. 
Published: March 2023

Context. We recently introduced a new method for simulating collisional gravitational N-body systems with approximately linear time scaling with N. Our method is based on the multi-particle collision (MPC) scheme, previously applied in fluid dynamics and plasma physics. We were able to simulate globular clusters with a realistic number of stellar particles (at least up to several times 106) on a standard workstation.
Aims. We simulated clusters hosting an intermediate mass black hole (IMBH), probing a broad range of BH-cluster and BH–average-star mass ratios, unrestricted by the computational constraints that affect direct N-body codes.
Methods. We set up a grid of hybrid particle-in-cell-MPC N-body simulations using our implementation of the MPC method, MPCDSS. We used either single mass models or models with a Salpeter mass function (a single power law with an exponent of −2.35), with the IMBH initially sitting at the centre. The force exerted by and on the IMBH was evaluated with a direct sum scheme with or without softening. For all simulations we measured the evolution of the Lagrangian radii and core density and velocity dispersion over time. In addition, we also measured the evolution of the velocity anisotropy profiles.
Results. We find that models with an IMBH undergo core collapse at earlier times, the larger the IMBH mass the shallower they are, with an approximately constant central density at core collapse. The presence of an IMBH tends to lower the central velocity dispersion. These results hold independently of the mass function of the model. For the models with Salpeter MF, we observed that equipartition of kinetic energies is never achieved, even long after core collapse. Orbital anisotropy at large radii appears to be driven by energetic escapers on radial orbits, triggered by strong collisions with the IMBH in the core. We measured the wander radius, that is the distance of the IMBH from the centre of mass of the parent system over time, finding that its distribution has positive kurtosis.
Conclusions. Among the results we obtained, which mostly confirm or extend previously known trends that had been established over the range of parameters accessible to direct N-body simulations, we underline that the leptokurtic nature of the IMBH wander radius distribution might lead to IMBHs presenting as off-centre more frequently than expected, with implications on observational IMBH detection.
Pflanzliche Ernährung und ausreichende Proteinzufuhr für ein gesundes Altern
Authors: Haß Ulrike , Norman Kristina 
Published: March 2023

ZusammenfassungDa die zunehmend ungesunde Ernährungs- und Lebensweise westlicher Industrienationen zur steigenden Prävalenz ernährungsbedingter, chronischer Erkrankungen beitragen, rückt eine
pflanzenbasierte Ernährung (PBE) immer mehr in den Fokus der Forschung. Insgesamt ist eine PBE mit vorteilhaften Effekten auf die kardiovaskuläre und metabole Gesundheit assoziiert. Dies
wird auf die höhere Nährstoffdichte und reduzierte Proteinzufuhr zurückgeführt, die sich auch günstig auf das Mortalitätsrisiko auszuwirken scheint. Unklar ist allerdings, wie günstig sich
eine PBE im höheren Lebensalter auswirkt, da longitudinale Daten speziell für die ältere Generation fehlen. Außerdem besteht im Alter (> 65 Jahre) ein Proteinmehrbedarf, sodass aufgrund
der geringeren Proteindichte und Proteinqualität einer PBE Bedenken bez. einer adäquaten Proteinversorgung bestehen. Sehr restriktive Ernährungsweisen werden aufgrund des zu erwartenden
Protein- und Nährstoffmangels insbesondere im höheren Lebensalter nicht empfohlen.
Can Classifications Adequately Represent Genital Malformations?
Authors: Kiblboeck Stephanie , Oppelt Peter , Oppelt Patricia , Stein Raimund , Ommer Stefanie , Pavlik Roman , Rall Katharina , Kongrtay Kuralay , Wagner Helga , Hermann Philipp , Trautner Philip Sebastian 
Published: March 2023

Abstract
Introduction Genital malformations are a common clinical occurrence that can be represented using different classifications. Reproducibility is an essential quality characteristic
for a classification, and it plays an important role, especially in consultations and the treatment of infertile patients and in obstetric management. The aim of this study is to
demonstrate the reproducibility and clinical practicality of three commonly used classifications: the ESHRE/ESGE (European Society of Human Reproduction and Embryology/ European Society
for Gynecological Endoscopy), VCUAM (Vagina Cervix Uterus Adnex-associated Malformation), and AFS (American Fertility Society) classifications.
Materials and Methods Sixty-five patients with female genital malformations were included in this prospective, multicenter, exploratory, observational study. All participants
underwent a clinical examination and a medical interview. The investigators were instructed to classify the presenting malformations according to the ESHRE/ESGE, VCUAM, and AFS
classifications using a structured questionnaire. Investigators were asked whether the malformation could be reproducibly classified (yes/no) and about the grade (grade 1–5 from “very
good” to “deficient”) they would assign to each classification. Classification assessment was queried for vagina, cervix, uterus, adnexa, and associated malformations and was scored from 1
to 5.
Results Reproducibility was rated as 80% (n = 52/65), 92.3% (n = 60/65), and 56.9% (n = 37/65) for the ESHRE/ESGE, VCUAM, and AFS classification, respectively. ESHRE/ESGE, VCUAM
and AFS were rated as “very good” or “good” for 83.3%, 89.2%, and 10.8% of vaginal malformations; for 75.8%, 87.5%, and 24.2% of cervical malformations; and for 89.7%, 89.5%, and 86.2% of
uterine malformations, respectively. VCUAM was rated as “very good” or “good” for 77.8% and 69.6% of adnexal malformations and associated malformations, respectively. ESHRE/ESGE and AFS
were rated as “sufficient” or "deficient” for 100% and 75% of adnexal malformations and for 77.3% and 69.6% of associated malformations, respectively.
Conclusion The prospective multicenter EVA (ESHRE/ESGE | VCUAM | AFS) study revealed that the organ-based ESHRE/ESGE and VCUAM classifications of female
genital malformations perform better in terms of reproducibility as well as in the assessment of individual compartments than the non-organ-based AFS classification.
An Efficient Route towards Quinazolinone Derivatives via I2/DMSO-Promoted Oxidative Decarboxylation of α-Amino Acids and Subsequent Oxidative Annulation Reaction
Authors: Bera Mrinal K. , Samanta Surya Kanta 
Published: March 2023

AbstractAn efficient and straightforward strategy to synthesize a wide range of quinazolinone derivatives from commercially inexpensive 2-aminobenzamides and various amino acids via molecular iodine promoted oxidative decarboxylation of α-amino acids, followed by oxidative cyclization reaction, is revealed. Operational simplicity, consistent yield, functional group tolerance and sustainability are the other noteworthy features of the reaction. A large number of quinazolinone derivatives were conveniently prepared employing the current strategy. The synthesis of other related heteroarenes, such as benzoxazole and benzothiazole derivatives, following the same reaction conditions broadens the scope of the method.
Design of Y-Shaped Trimers of Chiral Phase-Transfer Catalysts for the Asymmetric Alkylation of Amino Acid Derivatives
Authors: Liu Yan , Maruoka Keiji , Yu Shengyu , Liu Jiahao , Wang Zhe , Kato Terumasa 
Published: March 2023

AbstractA series of soluble Y-shaped trimers of chiral phase-transfer catalysts were synthesized and utilized in the asymmetric alkylation of amino acid Schiff bases. The length of the linker between the ammonium cation of the simplified Maruoka catalyst and a phloroglucinol moiety was varied and excellent yields and enantioselectivity were observed when using the Y-shaped trimer of chiral phase-transfer catalyst with an octamethylene linker. A theoretical study of the most efficient Y-shaped trimer of chiral phase-transfer catalyst suggests the chiral ammonium center of the catalyst is more exposed and thus more available in the reaction.
An Illustrative Case of Vein of Labbe Thrombosis Presented as a Glioma
Authors: Malikov Azad , Saylak Fatma Betul , Ertugrul Yavuz , Ocal Ozgur , Daglioglu Ergun 
Published: March 2023

AbstractCerebral vein thrombosis is a unique and rare type of cerebrovascular disease. The main challenge in identifying cerebral vein thrombosis is the presence of vague signs and symptoms that can resemble a variety of other intracranial pathologies. Our goal is to present the unique case of a young patient whose MRI scan revealed an abnormally enhancing tumor-like brain lesion that was heterogeneous in intensity and whose intraoperative view and histopathological findings were consistent with the vein of Labbe thrombosis, with ipsilateral transverse and sigmoid sinus involvement.
Strong-field ionization and AC-Stark shifted Rydberg states in OCS
Authors: Abu-samha Mahmoud , Madsen Lars Bojer 
Published: March 2023

Abstract
We present theoretical results for intensity-dependent above-threshold ionization (ATI) spectra from oriented OCS molecules probed by intense femtosecond laser pulses with wavelengths of 800 and 400 nm. The calculations were performed using the time-dependent Schrödinger equation within the single-active-electron approximation and including multielectron polarization effects. The results capture some of the experimental findings (Yu et al 2017 J. Phys. B: At. Mol. Opt. Phys.
50 235602), in particular when considering the sensitivity of the ATI spectra on the molecular orientation. We identify characteristic features in the ATI spectra which correspond to resonant multiphoton ionization via highly-excited Rydberg states are captured by the theory.
Directly-coupled well-wire hybrid quantum confinement lasers with the enhanced high temperature performance
Authors: Tai Hanxu , Wang Yuhong , Duan Ruonan , Zheng Ming , Lu Wei , Shi Yue , Zhang Jianwei , Zhang Xing , Ning Yongqiang , Wu Jian 
Published: March 2023

Abstract
It is well known that the laser diode performance will inevitably deteriorate when the device is heated. It has been a difficult issue to solve to date. In this letter, we are reporting a new solution to improve high-temperature performance of the laser diodes. The device uses a kind of directly-coupled well-wire hybrid quantum confinement (HQC) structure of the active medium based on the InGaAs–GaAs–GaAsP material system. This special HQC structure is constructed based on the strain-driven indium (In)-segregation effect and the growth orientation-dependent on-GaAs multi-atomic step effect. The measurement and analysis for the HQC laser sample show that the carrier leakage loss, the Auger recombination and gain-peak shifting due to heating are reduced in the HQC structure. It therefore increases the optical gain for lasing at high temperature. The power conversion efficiency is enhanced by >57% and the threshold carrier density drops by >24% at T ⩾ 360 K, in comparison to the traditional quantum-well laser performance. A higher characteristic temperature of 240 K is obtained as well. It implies the better thermal stability of the HQC laser structure. These achievements show a significant prospect for developing high thermo-optic performance of laser diodes.
Optically enhanced single- and multi-stacked 1.55 μm InAs/InAlGaAs/InP quantum dots for laser applications
Authors: Yu Xuezhe , Jia Hui , Dear Calum , Yuan Jiajing , Deng Huiwen , Tang Mingchu , Liu Huiyun 
Published: March 2023

Abstract
For the development of InAs/InP quantum dot (QD) lasers for 1.55 μm telecom wavelength, there are two main challenges: (1) morphological preference for quantum dashes over QDs, and (2) generally poor size uniformity of QDs (dashes). This study addresses the issues, in synchronous, by demonstrating the improved optical properties of 1.55 μm InAs/InP QDs at room temperature with excellent reproducibility. A high-density (∼4 × 1010 cm−2) dot-like morphology was initially attained via adjusting the growth parameters, albeit with a large full-width at half-maximum (FWHM) of ∼80 meV and a peak position of a wavelength longer than 1.55 μm. For improvement, the indium-flush technique was employed, which enhanced the uniformity of InAs QDs and substantially lowered the FWHM of five (single) stacked QDs to 50.9 meV (47.9 meV). This technique also blue-shifted the emission peak to 1530.2 nm (1522 nm). The InAs/InP QDs presented are appropriate for the fabrication of high-performance 1.55 μm lasers on InP (001) and, potentially, emerging light sources on the important Si (001).
Oxygen vacancy and hydrogen in amorphous HfO2
Authors: Sklénard Benoît , Cvitkovich Lukas , Waldhoer Dominic , Li Jing 
Published: March 2023

Abstract
Amorphous hafnium dioxide (a-HfO2) is widely used in electronic devices, such as ultra-scaled field-effect transistors and resistive memory cells. The density of oxygen vacancy (OV) defects in a-HfO2 strongly influences the conductivity of the amorphous material. Ultimately, OV defects are responsible for the formation and rupture of conductive filament paths which are exploited in novel resistive switching devices. In this work, we studied neutral OV in a-HfO2 using

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methods. We investigated the formation energy of OV, the binding energy of di-OVs, the OV migration, unperturbed and in the close presence of a hydrogen atom, as well as the migration of hydrogen atom towards OV. A shallow and short-range OV migration barrier (0.6 eV) exists in a-HfO2 in contrast to the barrier (2.4 eV) in crystalline HfO2. Nearby hydrogen has a limited impact on the OV migration; however, hydrogen can diffuse easily by hopping among OVs.