bluuebunny/crossref_metadata_2025_split huggingface dataset:
Correlation of umbilical cord arterial blood pH with meconium stained liquor
Authors: Kima Vanlal , Roy Indrani , Saikia Neelotparna 
Published: February 2023

Intrauterine passage of meconium may be due to fetal hypoxia, or it may simply indicate a normal gastrointestinal tract maturation. Umbilical cord blood pH is the best available criterion for detecting fetal hypoxia and making appropriate decisions about care after birth.To determine the correlation of umbilical cord arterial blood pH with meconium stained liquor and neonatal outcome. To determine whether the mode of delivery had any influence on the occurrence of acidemia in the neonate complicated with meconium stained liquor. A prospective observational study was conducted for a period of 6 months. Immediately following delivery in pregnancies complicated with meconium stained liquor, blood was drawn from the umbilical artery and sent for arterial blood gas (ABG) analysis. Neonatal outcome parameters and mode of delivery were then recorded in a pre-designed proforma. There was a statistically significant correlation between abnormal pH (acidosis) and thick meconium stained liquor. Neonatal outcome parameters like Apgar scores at 1 minute and 5 minutes, intravenous antibiotic administration, NICU admission and oxygen supplementation were statistically significant when correlated with the pH level.The degree of meconium thickness independently correlates with the composite adverse neonatal outcome. Cases with meconium stained liquor should be monitored vigorously with timely interventions and proper neonatal resuscitation, especially the ones with thick meconium stained liquor, in order to prevent adverse neonatal outcome.
Liver transaminase enzyme analysis as a predictor of poor maternal outcome in pregnant women with dengue
Authors: Panwar Megha , Bharti Rekha , Dabral Anjali , Kumar Anita , Suri Jyotsana , Singh Lovely 
Published: February 2023

To find out predictive value of elevated liver transaminases as a predictor of poor maternal outcome in pregnant women with dengue infection.Our study was a retrospective study, conducted in a tertiary care centre of North India from July 1 to December 31, 2021. Data of all the pregnant women with dengue infection during the above period was screened for maternal and fetal outcomes. Elevated liver transaminases in women who developed DHF, DSS and maternal mortality were the main outcome measures. Mode of delivery, obstetric complications, medical complications (Dengue Hemorrhagic Fever, Dengue shock syndrome and Acute Respiratory Distress Syndrome) and KFT for prediction of maternal mortality were the secondary outcome measures.The association of liver transaminases derangement with stage of dengue at diagnosis were analysed using Fisher’s exact test. Data analysis was done with Statistical Package for Social Sciences (SPSS) software, IBM manufacturer, Chicago, USA, version 21. P value of less than 0.05 was considered statistically significant. A total of 35 women were included in the study. The mean age was 23.49 + 2.94 years. Acute respiratory distress syndrome, acute kidney injury, atonic PPH, and puerperal sepsis developed in 6(17.14%), 7(20%), 4(8.57%), and 10 (28.57%) women respectively. The maternal mortality rate was 25.71%. All women who developed DHF (3 women) and DSS (9 women) had altered liver enzymes. Alanine transaminase has very high sensitivity (100%) and specificity (76.92%) as a predictor of maternal mortality in pregnant women with dengue, (p&#60;0.05). Similarly, serum creatinine levels at a value of more than 0.9 mg/dl had a sensitivity and specificity of 88.89% and 92.31%, respectively for predicting maternal mortality in pregnant women with dengue, (p&#60;0.05). Conclusion: Elevated liver transaminases can be used as predictors of poor maternal outcome in pregnant women with dengue infection.
Observational study of induction of labour versus expectant management in overdate pregnancies amongst Indian women
Authors: Das Monica , Damania Kaizad R , Bansal Vandana , Kale Deepali 
Published: February 2023

The present study was a prospective observational study done to evaluate elective induction of labour (e-IOL)* in overdate pregnancies (40 1/7 to 40 6/7 weeks) versus expectant management (EM)* up to 41 weeks. The primary objective was to compare rates of Caesarean section among the two groups. Study design: Women at 40 weeks of gestation satisfying the inclusion and exclusion criteria were recruited for the study. Total sample size was 112. The e-IOL group 1, included 56 participants who were induced at 40 1/7 to 40 6/7 weeks of gestation and EM group 2 had 56 participants, who were given expectant management till 41 weeks of gestation. Group 2 was further divided as group 2a who went into spontaneous labour while on expectant management and group 2b as those who were induced while on expectant management for maternal / fetal reasons or ≥ 41 0/7 weeks of gestation.Expectant management till 41 weeks of gestation beyond the due date increased the likelihood of spontaneous labour without adversely affecting the perinatal outcome. 73.2% of participants went into spontaneous labour in the EM group and 78% of them delivered vaginally. Caesarean section rates were lesser with EM (37.5%) as compared to e-IOL (58.9%) in our study (p=0.002).Caesarean section rates were lesser among women with post date pregnancies when expectant management was followed as compared to elective induction of labour. No difference in perinatal outcomes was noted amongst the two groups. Participants who went into spontaneous labour when on expectant management were more likely to deliver vaginally.
A profile of abortion in a tertiary care centre: An observational study
Authors: Narasimha Chaitra , Sudha R  
Published: February 2023

The recent years have seen rise in unintended pregnancy which includes unwanted and mistimed pregnancy. Despite the conducive environment of legal abortion in India through MTP Act, many women resort to unsafe methods of abortion. In India, estimated abortions in 2015 were 15.6 million. The overall rate of abortion was estimated to be 4.8%, among which 67.1% of abortions were classified to be unsafe. Thus, the aim of the study is to analyze the demographic profile of patients, reason for seeking abortion and evaluation of significant adverse outcome and management. This was a hospital-based observation study carried out in the department of OBG in MMC&RI, Mysuru during the period January 2019 to December 2020. 100 women seeking MTP and 100 women presenting to hospital for help following the consumption of over the counter pills were included in the study. : 100 women with self-consumption of pills presented to hospital with complaints of heavy bleeding (35%), spotting PV (22%) and pain abdomen (15%). Most were married, belonging to lower socioeconomic status with age of 21-25 years (42%), followed by 26 – 30 years (22%). In 100 women seeking MTP, congenital fetal anomalies (51%) was the main indication, followed by contraception failure (36%). In comparison to the women seeking abortion services under medical supervision, the complication rates were higher in unsupervised group. This included retained products of conception (25%), moderate anemia (12%), severe anemia (7%), shock (3%), sepsis (4%) requiring surgical evacuation (51%), medical management (46%), anemia correction (17%), ICU admission (7%) and emergency laparotomy (3%). The cornerstone is motivation and encouragement of women to adapt family planning services to reduce unintended pregnancy. For women needing these services, accessibility and comprehensive education regarding unsafe abortion is needed. Legislation and strict policy is required for the use of MTP pills, so as to reduce the sales without prescription.
Terapi Perilaku Anak Autisme Usia Sekolah Dasar Berbasis Applied Behavioral Analysis (ABA) di Pusat Layanan Disabilitas dan Pendidikan Inklusi Provinsi Kalimantan Selatan
Authors: Amin Barkatullah , Azkiya Siti Rahmatul , Ramadan Willy 
Published: February 2023

Autisme adalah gangguan neurobiologis yang kemudian mempengaruhi fungsi otak sedemikian rupa sehingga anak seringkali memiliki hambatan interaksi dan komunikasi dengan orang lain. Anak dengan autisme seringkali juga memiliki perbedaan pada proses pertumbuhan maupun perkembangan dari anak tanpa autisme, baik dari interaksi sosial maupun emosionalnya, sehingga memerlukan layanan pendidikan dan perlakuan yang khusus, sehingga fungsi terapi sangat penting untuk kemajuan perkembangan dan pertumbuhan anak dengan autisme. Penelitian ini bertujuan untuk memberikan gambaran tentang bagaimana pelaksanaan layanan terapi terhadap anak dengan autisme pada Pusat Layanan Disabilitas dan Pendidikan Inklusi (PLDPI) provinsi Kalimantan Selatan. Dalam penelitian studi kasus ini penulis menggunakan metode deskriptif kualitatif yang akan menguraikan hasil penelitian dengan bentuk teks naratif tentang subyek penelitian secara satu persatu . Hasil penelitian ini menunjukkan bahwa proses terapi perilaku yang diterapkan kepada dua subyek penelitian melalui metode ABA (Applied Behavioral Analysis) yang dilaksakanan pada Pusat Layanan Disabilitas dan Pendidikan Inklusi (PLDPI) secara signifikan telah memberikan kemajuan terhadap peningkatan perilaku dan kemampuan individu-individu anak dengan Autisme.
Çocuk Yoğun Bakımda Yatan Hastalar İçin İstenen Çocuk Ve Ergen Psikiyatrisi Konsültasyonlarının Değerlendirilmesi
Authors: SARAÇ SANDAL Özlem , GÖNÜLLÜ Ahmet , KAVURMA Canem , CEYLAN Gokhan , ATAKUL Gülhan , SEVEN Pınar , SARI Ferhat , KARAARSLAN Utku , AĞIN Hasan 
Published: February 2023

Amaç: Pediyatrik Yoğun Bakım Ünitesinde yatan bedensel hastalığı olan çocuklarda davranışsal-duygusal psikopatolojiler sıklıkla gelişmektedir. Fiziksel hastalığa eşlik eden bu ruhsal durumlar tedaviyi uyumu bozarak olumsuz sonuçlara yol açabilmektedir. Bu çalışmada çocuk yoğun bakım ünitemizde kritik hastalık nedeniyle izlenen hastalar için son 3 yıl içinde istenen çocuk psikiyatri konsultasyonlarının değerlendirilmesi amaçlanmıştır
Gereç ve Yöntem: Çalışmamızda 2019-2022 yılları arasında Dr. Behçet Uz Çocuk Hastanesi Çocuk Yoğun Bakım ünitesinde izlenen çocuk psikiyatrisi konsültasyonu istenen hastaların verileri geriye dönük olarak taranmıştır. Hastaların demografik özellikleri, bedensel hastalık tanıları, konsültasyonların istenme nedenleri, konsültasyon sonucunda saptanan psikiyatrik tanılar ve bunun sonucunda tedavi uygulanıp uygulanmadığı, verilen bir tedavi olması durumunda hangi medikal tedavilerin tercih edildiği, psikiyatrik tedavi ve izlem sürecine ilişkin veriler kaydedilmiştir
Bulgular: Üç yıllık sürede çocuk yoğun bakımda izlenen çocukların 118’i (%4,9) için psikiyatri konsültasyonu istenmiştir. Konsültasyon istenenlerin çoğu kızdır (%61,9) ve 12 yaş veya üzeri yaşta % 71,4 hasta bulunmaktadır. En sık konsültasyon isteme nedeni özkıyım girişimleri (%33,1) ve depresif görünüm (%25,5) olarak saptanmış olup en sık konulan tanı majör depresif bozukluk ve uyum bozukluğudur. Olguların %31’inde psikotrop ilaç başlanmış olup erkekler ve kızlar arasında anlamlı fark saptanmamıştır.
Sonuç:
Bu çalışma bedensel hastalığı olan kritik çocuk yoğun bakım hastalarında ruhsal hastalıkların sık görülmesine rağmen psikiyatri konsültasyonu istenme oranlarının düşük olduğunu saptamıştır. Bu durum yoğun bakım hekimlerinin belirtileri anlama ve değerlendirme konusunda hastaların bilinç durumları ve primer hastalıkları nedeniyle güçlükler yaşadığına işaret etmektedir. Bu nedenle çocuk psikiyatrisi ile birlikte multidisipliner bir yaklaşım izlemeleri ve işbirliği içinde olmaları hastanın tedaviye uyumunu arttırarak yatış sürelerini kısaltacaktır.
COMPARISON OF PREOPERATIVE BOWEL PREPARATION MODELS OF PATIENTS WHO UNDERWENT SURGERY FOR COLORECTAL CANCER
Authors: KARTAL Bahadır , BOZKURT Mehmet Abdussamet , SEYHUN Cemal 
Published: February 2023

Background
The most prevalent cancer in society is colorectal cancer (CRC). Studies aiming to lower surgical morbidity and mortality have found a significant contribution from preoperative bowel preparation. Models for bowel preparation included mechanical cleaning, the use of antibiotics, and control groups. We compared preoperative bowel preparation for elective colorectal cancer and evaluated its effects in this study.
Material and Methods
Preoperative bowel preparation model was used to prospectively split 144 patients (n=144) with colorectal cancer into four groups. Patients in the first group (Group I) underwent mechanical bowel preparation (MBP), followed by oral antibiotic therapy (OAB) and MBP in the second group (Group II), intravenous antibiotic therapy (IVAB), MBP, and OAB in the third group (Group III), and no bowel preparation in the fourth group (Group IV). Demographic information, anastomotic leakage, surgical site infection, intraabdominal abscess, postoperative ileus, and death were compared between patients.
Results
Groups I, II, III, and IV of the study each had 35 patients, 38 patients, 35 patients, and 36 patients, respectively. There was no statistically significant difference between the four groups when the groups were evaluated by age, gender, and ASA (American Society of Anesthesiologists) score (p> 0.05). There were significant differences between surgical site infection (SSI), intraabdominal abscess, and anastomosis leaking (p0.05). Mortality and postoperative ileus did not differ significantly (p > 0.05).
Conclusion
We consider that the bowel preparation approach of mechanical colon cleansing and antibiotic administration is appropriate for patients who have had surgery owing to elective CRC.
Perivascular Administration of Hyaluran-Cyanoacrylate Complex Gel for Deep Venous Reflux
Authors: RODOPLU Orhan 
Published: February 2023

Objective: Deep venous insufficiency is an important health issue affecting the population worldwide. In this study we aimed to assess the effectiveness and safety of a novel antireflux treatment procedure in patients with primary deep vein insufficiency.
Methods: Between October 2016 and December 2018, 81 valvular leak operations consisting of perivenous hard gel injection were performed in 81 patients with primary deep venous insufficiency. The clinical symptoms of the patients were between C3-C6 according to the CEAP clinical classification. Venous insufficiency associated with only one deep venous valve was verified with Doppler ultrasonography. Patients were assessed with physical and ultrasound examination on the follow-up visits, which were achieved on the third day and at the first, sixth, and twelfth months. The nonexistence of reflux in the treated valve level was defined as the success of the procedure. Any reflux, which lasted 0.5 seconds or more, was regarded as a lack of success.
Results: The ages of the patients ranged between 32 and 78. All the patients had deep venous insufficiency. The follow-up could be achieved in all the patients. The mean volume of the gel administered was 2.4±0.9 ml. The mean procedure duration was 22.3±8.9 (range 14–42) minutes. The procedures could be performed successfully in all of the patients confirmed perioperatively and on the third day of follow-up with the elimination of reflux. The sixth-month follow-up, with the same vein diameter after the treatment without any reflux, revealed the same findings as to the first-month follow-up. The treatment was not associated with any significant morbidity or mortality. The VCSS decreased significantly when preprocedural and twelfth-month VCSS were compared as 21.8 ± 4.8 and 3.8±0.7, respectively (p
Differential CD4+ T-Cell Cytokine and Cytotoxic Responses Between Reactivation and Latent Phases of Herpes Zoster Infection
Authors: Jin Wenjie , Fang Mike , Sayin Ismail , Smith Carson , Hunter Jeffrey , Richardson Brian , Golden Jackelyn , Haley Christopher , Schmader Kenneth , Betts Michael , Cameron Cheryl , Tyring Stephen , Cameron Mark , Canaday David 
Published: February 2023

Background: CD4+ T cells are a critical component of effective immune responses to varicella zoster virus (VZV), but their functional properties during the reactivation acute vs latent phase of infection remain poorly defined.
Methods: Here we assessed the functional and transcriptomic properties of peripheral blood CD4+ T cells in persons with acute herpes zoster (HZ) compared to those with a prior history of HZ infection using multicolor flow cytometry and RNA sequencing.
Results: We found significant differences between the polyfunctionality of VZV-specific total memory, effector memory, and central memory CD4+ T cells in acute vs prior HZ. VZV-specific CD4+ memory T-cell responses in acute HZ reactivation had higher frequencies of IFN-γ and IL-2 producing cells compared to those with prior HZ. In addition, cytotoxic markers were higher in VZV-specific CD4+ T cells than non-VZV-specific cells. Transcriptomic analysis of ex vivo total memory CD4+ T cells from these individuals showed differential regulation of T-cell survival and differentiation pathways, including TCR, cytotoxic T lymphocytes (CTL), T helper, inflammation, and MTOR signaling pathways. These gene signatures correlated with the frequency of IFN-γ and IL-2 producing cells responding to VZV.
Conclusions: In summary, VZV-specific CD4+ T cells from acute HZ individuals had unique functional and transcriptomic features, and VZV-specific CD4+ T cells as a group had a higher expression of cytotoxic molecules including Perforin, Granzyme-B, and CD107a.
Pengaruh social media marketing instagram dan word of mouth terhadap minat berkunjung di savaya day club bali
Authors: Anggraeni Ni Luh Putu Putri , Jayendra Putu Sabda , Kuntariati Utik 
Published: February 2023

Social media marketing adalah upaya pemasaran yang menggunakan media sosial sebagai salurannya. Social Media Marketing dapat digunakan sebagai bagian dari strategi bisnis untuk membangun sebuah komunitas, keterlibatan dan interaksi terus menerus dengan pelanggan. Word of Mouth adalah pernyataan tentang produk yang disampaikan kepada orang lain (Artanti, 2016). Word of Mouth yang diperoleh dari seseorang yang memiliki kecintaan terhadap sebuah produk lebih nyata dan jujur. Tujuan penelitian ini Untuk menganalisis dan mengetahui apakah Media Sosial Marketing Instagram dan Word of Mouth berpengaruh terhadap minat berkunjung di Savaya Day Club Bali. Hasil dari penelitian ini adalah Ada pengaruh positif dan signifikan secara parsial antara Sosial Media Marketing terhadap Minat Berkunjung ke Savaya Dayclub Bali hal ini dapat dibuktikan dari analisis regresi ?1 (0,203), dan nilai signifikan (0,000)<(0,05), dan ada pengaruh positif dan signifikan secara parsial antara Word of Mouth terhadap Minat Berkunjung ke Savaya Dayclub Bali hal ini dibuktikan dari analisis regresi ?2 (0,572) dan nilai signifikan (0,000)<(0,05) serta ada pengaruh yang positif dan signifikan secara simultan antara Sosial Media Marketing dan Word of Mouth terhadap minat berkunjung ke Savaya Dayclub Bali. Hal ini dibuktikan dari nilai analisis regresi Y= 0,195 + 0,203X1 + 0,572 X2 + ? serta daat dilihat dari Uji F test diperoleh nilai nilai signifikansi 0,000 ? 0,05.

Social media marketing is a marketing effort that uses social media as a channel. Social Media Marketing can be used as part of a business strategy to build a community, interaction and continuous interaction with customers. Word of mouth is a statement about a product that is conveyed to others (Artanti, 2016). Word of Mouth obtained from someone who has a love for a product is more real and honest. The purpose of this study is to analyze and find out whether Instagram and Word of Mouth Social Media Marketing have an effect on interest in visiting Savaya Day Club Bali. The results of this study are that there is a positive and partially significant effect between Social Media Marketing on interest in Savaya Dayclub Bali, this can be proven from regression analysis ?1 (0.203), and the value (0.000) < ? (0.05), and there is an influence Positive and partially significant between Word of Mouth on Interest growing significantly to Savaya Dayclub Bali this is evidenced from analysis ?2 (0.572) and value (0.000) < ? (0.05) and there is a positive and simultaneous influence between Social Media Marketing and Word of Mouth on interest in visiting Savaya Dayclub Bali. This is evidenced from the value of the regression analysis Y = 0.195 + 0.203X1 + 0.572 X2 + and the data from the F test obtained a significance value of 0,000 ? 0,05.
Analisis implementasi green hotel di sarinbuana eco lodge
Authors: Dewi Ni Putu Intan Putri Saraswati , Jayendra Putu Sabda , Muliadiasa I Ketut 
Published: February 2023

Penelitian ini bertujuan untuk mengetahui implementasi dari dimensi green hotel dan manajemen pengelolaannya.di Sarinbuana Eco Lodge. Penelitian ini penting guna mendorong industri perhotelan untuk mengadaptasi langkah-langkah ramah lingkungan untuk keberlanjutan. Jenis dari ini penelitian ini yaitu penelitian kualitatif deskriptif. Teknik pengumpulan data yang digunakan dalam penelitian ini yaitu wawancara, observasi dan kuesioner yang mengacu pada Pedoman Pelaksanaan Green Hotel di Indonesia yang diterbitkan oleh Kementrian Pariwisata dan Ekonomi Kreatif tahun 2016. Tehnik analisis data yang digunakan dalam penelitian ini adalah tehnik analisis data dari Miles dan Huberman. Hasil penelitian ini menunjukkan persentase implementasi green hotel sebesar 83,73 % dari dimensi green hotel serta manajemen pengelolaan yang mana menunjukkan bahwa implementasi green hotel di Sarinbuana Eco Lodge sudah berjalan dengan cukup baik dan sesuai dengan Pedoman Pelaksanaan Green Hotel di Indonesia. Sebagai suatu akomodasi, Sarinbuana Eco Lodge mampu menciptakan kesimbangan antara lingkungan, sosial serta ekonomi melalui penerapan dimensi-dimensi green hotel pada seluruh operasionalnya.

This study aims to determine the implementation of the green hotel dimension and its management at Sarinbuana Eco Lodge. This research is important to encourage the hotel industry to adopt environmentally friendly measures for sustainability. The type of this research is descriptive qualitative. The data collection techniques used in this study were interviews, observations and questionnaire referring to Guidelines for the Implementation of Green Hotels in Indonesia published by the Ministry of Tourism and Creative Economy in 2016. The data analysis technique used in this study is the analysis technique by Miles and Huberman. The results of this study indicate that the percentage of green hotel implementation is 83, 73 % of the green hotel dimension and green management which shows that the implementation of green hotel at Sarinbuana Eco Lodge has been going quite well and in accordance with the Guidelines for the Implementation of Green Hotels in Indonesia. As an accommodation, Sarinbuana Eco Lodge is able to create a balance between the environment, social and economy through the application of green hotel dimensions in all its operations.