bluuebunny/crossref_metadata_2025_split huggingface dataset:
Benchmarking commercial depth sensors for intraoperative markerless registration in neurosurgery applications
Authors: Villa Manuel , Sancho Jaime , Rosa-Olmeda Gonzalo , Chavarrias Miguel , Juarez Eduardo , Sanz Cesar 
Published: January 2025

Abstract

Purpose: This study proposes a generalization of markerless patient registration in image-guided neurosurgery based on depth information. The work builds on previous research to evaluate the performance of a range of commercial depth cameras and two different registration algorithms in this context.
Methods: A multimodal experimental setup was used, testing five depth cameras in seven configurations. Fiducial Registration Error (FRE) and Target Registration Error (TRE) metrics were calculated using Iterative Closest Point (ICP) and Deep Global Registration (DGR) algorithms. A phantom head model was used to simulate clinical conditions, with cameras positioned to capture the face and craniotomy regions.
Results: The best-performing cameras, such as the D405 and Zed-M+, achieved TRE values as low as 2.36 ± 0.46 mm and 2.49 ± 0.35 mm, respectively, compared to manual registration that obtains a 1.37 mm error. Cameras equipped with texture projectors or enhanced depth refinement demonstrated improved performance. The proposed methodology effectively characterized the suitability of the camera for the registration tasks.
Conclusions: This study validates an adaptable and reproducible framework to evaluate depth cameras in neurosurgical scenarios, highlighting D405 and Zed-M+ as reliable options. Future work will focus on improving depth quality through hardware and algorithmic improvements. The experimental data and the accompanying code were made publicly available to ensure reproducibility.
Gumbel function parameters estimation for annual maximum precipitation data using the Whale Optimization Algorithm (WOA)
Authors: ARGANIS-JUÁREZ MARITZA L , Preciado-Jiménez Margarita E. , Mendoza-Reséndiz Alejandro , Roblero-Hidalgo Rodrigo 
Published: January 2025

Abstract

Hydrological variables frequency analysis is crucial for designing and operating hydraulic infrastructure. The Gumbel distribution is commonly used to model extreme events like floods. This study investigates the Whale Optimization Algorithm (WOA) use, a metaheuristic inspired by humpback whale hunting, to estimate the parameters of the Gumbel distribution for annual maximum precipitation data from a climatological station located at Hidalgo State, Mexico. The WOA was compared with moments method. Performance was evaluated using adjustment (EEA) standard error and root mean square error (RMSE). Results demonstrated comparable performance between these two methods. The WOA offers several advantages, including flexibility and adaptability to complex optimization problems. This study highlights the potential of the WOA as a valuable tool for parameter estimation in hydrological frequency analysis, improving the accuracy and reliability of designs for hydraulic structures under conditions of uncertainty and climate change.
Relationship between Anogenital Distance and Testicular Position in Male Infants with Cryptorchidism with and without Hypospadias
Authors: Nagla Salah , Elrifaey Shaymaa , abdelnabi hend , hagras ayman , arafa ahmed , hamza mohamed , dawood waleed 
Published: January 2025

Abstract

Purpose
Anogenital distance (AGD) may indicate hypoverilization and subsequently serve as a predictor future reproduction. In both undescended testis with and without hypospadias, our goal was to study the relationship between testicular position and AGD.
Methods
From March 2021 to January 2023, the study was conducted on male infants with and without hypospadias and age-matched controls. Based on the infants' ages, we divided them into four. Group I: under six months, Group II: 7–12 months, Group III: between a year and eighteen months, and Group IV: 19 months up to two years of age. From the verge of the anus to the penile base, the AGD was measured. Clinical examination resulted in the classification of testicular location as high scrotal, inguinal, and non-palpable.
Results
Patients with cryptorchidism had AGD means that were substantially lower than those of controls in Groups I, II, III, and IV, respectively (31 ± 2, 33 ± 3), (35.9 ± 4, 37.9 ± 5), (39.9 ± 1.2, 41 ± 1.5), and (40 ± 1.9, 44 ± 1.7). The group of patients with cryptorchidism and hypospadias differed significantly from the controls and those without hypospadias. AGD in patients with upper scrotal locations was substantially shorter. Penile length and AGD of the examined groups exhibited a positive and significant connection.
Conclusions
Shorter AGD is linked to a higher prevalence of hypospadias and cryptorchidism in male babies in comparison to normal children. The position of the undescended testis is higher in relation to a shorter AGD.
Investigating the Association Between Maternal Folic Acid Supplementation and the Occurence of Ankyloglossia in Newborns
Authors: Kesuma Yudianita , Soedjadhi Rismarini , Bernolian Nuswil , Lestari Peby Maulina , Liana Phey , Indrayady Indrayady , Ramadanti Afifa 
Published: January 2025

Abstract

Background
In both popular and scientific literature, an association between tongue tie (ankyloglossia) and folic acid intake during pregnancy is often suggested, although this has not been systematically investigated. Some literature considers this association to be anecdotal. This study aimed to clarify the role of folic acid during pregnancy in the development of tongue tie babies.
Methods
A cross-sectional study was conducted from August to September 2021. Participants were pregnant women who delivered at Moh. Hoesin hospital and Hermina hospital in Palembang. Subjects were recruited using consecutive sampling. Tongue tie in babies was determined using the Hazelbaker’s Assessment Tool for Lingual Frenulum Function (HATLFF). Folic acid levels maternal serum were measured using ELISA DRG® testing.
Results
Among 144 mothers included in the study, 26.6% of their babies were diagnosed with tongue tie. There was a statistically significant associaton between maternal serum folic acid levels and the occurrence of tongue tie (p = 0.033, OR = 2.130 95% CI = 1.002–4.525). The risk factors for elevated maternal folic acid serum included the consumption of pasta, melon, and lettuce during pregnancy (p = 0.015, OR = 4.05; p = 0.014, OR = 3.91; p = 0.015, OR = 0.31), respectively.
Conclusion
The prevalence of tongue tie was high and showed a significant association with elevated level of maternal serum folic acid.
Exponential-trigonometric Optimization Algorithm with Multi-Strategy Fusion for UAV three-dimensional path planning
Authors: Xu Tao , Chen Chaoyue , Meng Fanfan , Ma Dongdong 
Published: January 2025

Abstract

With the rapid advancement of Unmanned Aerial Vehicle (UAV) technology, trajectory planning has become a focus research. This paper proposes a three-dimensional path planning method for UAV based on an improved Exponential-triangle Optimization Algorithm (IETO). By constructing a multi-objective optimization function that considers factors such as path length, flight altitude, and turning angle, a comprehensive evaluation of path quality is able to be achieved. The IETO algorithm incorporates interval-constrained logistic chaotic mapping, dynamic reverse learning strategy, and an adaptive artificial bee colony algorithm (ABC) escape mechanism within the ETO algorithm. These enhancements prevent premature convergence to local optima. Through benchmark function tests on the CEC2017 test set and simulations in peak threat environments, the IETO algorithm demonstrated superior robustness. Compared to mainstream algorithms like GWO and GJO, IETO achieves the best performance in 62% of function tests. It also demonstrates exceptional performance in solving complex functions, effectively balances exploration and exploitation capabilities. In mountainous environments, the IETO algorithm generates the smoothest paths with the lowest costs and quickly converges to the optimal solution.
Psychometric Analysis of the Spanish Version of the Évaluation du Vécu de l’Anesthésie Générale EVAN-G Questionnaire in Adult Surgical Patients in Argentina: A Cross- Sectional Study
Authors: Baloira Federico Manuel , Salcedo Lisa Sanchez , Novas Delfina Sanchez , Domenech Gonzalo , Vazquez Fernando Ramon , Terrasa Sergio Adrian , Guzzo María Eugenia Garcia 
Published: January 2025

Abstract

Background
Patient satisfaction during the perioperative period involves multiple facets of care. Despite its clinical relevance, validated tools to assess patient satisfaction in Spanish-speaking populations are scarce. The Évaluation du Vécu de l’Anesthésie Générale questionnaire, originally developed in French and subsequently adapted to Spanish, offers a comprehensive framework for evaluating perioperative satisfaction.
Methods
A cross-sectional study was conducted at a tertiary private hospital in Buenos Aires. We performed a psychometric evaluation including confirmatory factor analysis, assessment of convergent and discriminant validity, and internal consistency analysis.
Results
The model showed acceptable global fit indices: Root Mean Square Error of Approximation (0.073), Comparative Fit Index (0.956), and Tucker-Lewis Index (0.951). Most dimensions—information, privacy, discomfort, waiting, and care—demonstrated strong validity (Average Variance Extracted ≥ 0.50) and reliability (Composite Reliability ≥ 0.70). However, the Pain dimension exhibited suboptimal performance, with low validity and reliability.
Conclusions
The Spanish version of the Évaluation du Vécu de l’Anesthésie Générale questionnaire is an effective tool for measuring patient satisfaction across most dimensions. However, challenges in the Pain dimension highlight the need for refinement in this area or the potential use of a different tool to assess it more accurately. These findings present this questionnaire as an innovative tool for promoting patient-centered care in Latin America, meeting a vital need for culturally tailored measures of perioperative satisfaction
Low-power red laser and ultraviolet A LED irradiation alters mRNA levels from DNA repair genes in Saccharomyces cerevisiae
Authors: Nunes Brenno de Mendonça , Pinheiro Daphne , de Oliveira Márcia Betânia Nunes , Pires Bruno Ricardo Barreto , Mencalha Andre Luiz , Dantas Flávio José da Silva , Fonseca Adenilson de Souza da 
Published: January 2025

Abstract

Therapeutic protocols based on photobiomodulation (PBM) have been used to treat wounds, pain, and inflammation. On the basis of PBM is the absorption of non-ionizing radiation at low-power by the cytochrome c oxidase, producing reactive oxygen species. Such free radicals could cause oxidative damage in DNA, which is repaired by base excision repair (BER) and nucleotide excision repair (NER) mechanisms. Up to date, few studies assessed oxidative damage in DNA as consequence of low-power red lasers and ultraviolet A LED on expression of DNA gene repair. This study aimed to determine the expression of genes related to BER and NER pathways in Saccharomyces cerevisiae after irradiation with low-power red laser and ultraviolet A LED. Cultures of S. cerevisiae were exposed to low-power red laser (660 nm, 21.2 J/cm2, 205 s, 99 mW) and ultraviolet A LED (390 nm, 6 J/cm2, 205 s, 7 mW), incubated for 1 hour, total mRNA was extracted, cDNA was synthesized, and OGG1, APN1, RAD1 and RAD10 mRNA levels in S. cerevisiae FF18733 were evaluated by RT-qPCR. The results indicated that exposure to low-power red laser does not induce changes in gene expression, but exposure to ultraviolet A LED alone and simultaneously with low-power red laser significantly reduce APN1 and RAD10 mRNA levels in S. cerevisiae. Exposure to low-power red laser could not affect mRNA from BER and NER, but ultraviolet A LED and simultaneous low-power red laser and ultraviolet A LED could decrease gene expression of BER and NER pathways in S. cerevisiae.
Epidemiological Landscape of injuries Associated with Motor Traffic Accidents in Southern Tanzania
Authors: Shedura Vulstan James , Ngomo Geofrey John , Moses Lameck Titus 
Published: January 2025

Abstract

Background Motor Traffic Accidents (MTAs) are a global public health concern, disproportionately impacting low- and middle-income countries (LMICs) like Tanzania. Injuries from road traffic accidents (RTAs), impose significant morbidity, mortality, and economic burdens. However, data on the epidemiological landscape of MTA-related injuries in Southern Tanzania remain limited. This study aimed to evaluate the epidemiological characteristics of injuries caused by MTAs in Southern Tanzania.Methods A retrospective, health-facility-based cross-sectional study was conducted in five referral hospitals across the Mtwara and Lindi regions. Data from 154 patients who sustained MTA-related injuries between January and December 2023 were analyzed. Participants were selected using systematic random sampling, and socio-demographic and clinical data were abstracted from medical records. Descriptive and inferential statistics were used for analysis.Results The majority of participants were male (76%), with a median age of 31.5 years (IQR: 22–49). Self-employment (63%) and primary education (55.8%) were the most common occupational and educational statuses, respectively. Head injuries (28.6%) and musculoskeletal injuries (26%) were the most prevalent, with tibia fractures and chest injuries reported in 14.3% and 7.1% of patients, respectively. Gender differences were notable, with males experiencing higher rates of visceral injuries (6.8%) and chest injuries (7.7%), while females had higher rates of musculoskeletal injuries (35.1%).Conclusions MTA-related injuries, particularly head injuries and musculoskeletal trauma, are prevalent in Southern Tanzania, with significant socio-demographic disparities. These findings emphasize the need for targeted public health strategies to improve road safety, enhance access to surgical care, and reduce the burden of MTAs in this region.
Delayed bedtime on workdays increases the risk of gallstones: a cross-sectional study based on NHANES 2017–2020
Authors: Liu Man , Gong Yanqing , Su Yingxi , Ji Yinglan , Bao Suriguge , Shen Meng , Zhang Xue , Zhou Simin , Guo Liping , Ran Ying , Li Yanni , Li Man , Zhou Lu 
Published: January 2025

Abstract

Background
The relationship between sleep and gallstones(GS) has rarely been reported. We aimed to investigate whether sleep traits are associated with the prevalence of GS.
Methods
A cross-sectional study was conducted using data from the National Health and Nutrition Examination Survey 2017–2020. Participants aged ≥ 20 years with complete information on sleep and GS questionnaires were enrolled. Binary logistic regression analyses were performed to investigate the relationship between sleep traits (bedtime, wake-up time, sleep duration, sleep disorders) and GS while adjusting for confounding factors. Stratified and interaction analyses were conducted to find whether some factors modified the association.
Results
A total of 7,329 participants were included in this study, and 736 had a self-reported history of GS. In the fully adjusted model, we found that each hour of delay in workday bedtime was associated with an 8.6% increase in the risk of GS (OR = 1.086, 95% CI 1.022–1.154, P = 0.026). Compared to individuals with a workday bedtime between 18:00-≦20:00, those sleeping later, between 22:00-≦24:00 faced a higher risk of GS (OR = 5.824, 95% CI 1.629–20.827, P = 0.035), while the risk was even greater for those sleeping between 24:00-≦06:00 (OR = 6.676, 95% CI 1.758–25.356, P = 0.032). Subgroup analyses revealed that age influenced the association between workday bedtime and the risk of GS. In participants aged > 40 years, the risk of GS increased significantly with delayed workday bedtime (OR = 1.139, 95% CI 1.065–1.219, P = 0.009), while this association was not observed for those ≤ 40 years. Furthermore, the fully adjusted model found no significant association between wake-up time, sleep duration, or sleep disorders and the prevalence of GS.
Conclusions
Delayed workday bedtime is associated with a higher risk of GS. Age mediates the relationship between workday bedtime and the prevalence of GS. Notably, for individuals aged > 40 years, the risk of GS increased significantly with delayed bedtime on workdays.
Fostering Supportive Online Communities: Exploring Bystander Intervention in Cyberbullying Prevention
Authors: Shoaib Muhammad , Abbasi Irshad Ahmed 
Published: January 2025

Abstract

Cyberbullying can profoundly impact individuals' mental health, leading to increased feelings of anxiety, depression, and social isolation. Psychological research suggests that cyberbullying victims may experience long-term psychological consequences, including diminished self-esteem and academic performance. The widespread use of social media platforms among university students has raised major concerns over cyberbullying, which can have detrimental effects on student mental well-being and academic performance. We designed CBNet, a convolutional neural network (CNN)-based model for detecting cyberbullying among student social media groups. We developed a comprehensive dataset collected from several social media platforms popular among university students. Our results demonstrate that CBNet notably outperforms both the traditional machine learning approaches and the RNN-based model and presents an outstanding value of precision, recall, and F1-score overall, with an Area Under the ROC Curve significantly higher than 0.99. Combined with the fact that the issue of cyberbullying always remains relevant, these results suggest the high feasibility of our suggested approach to the detection of incidents. Given our results, CBNet could be used as a preventative tool for educators, administrators, and community managers to combat cyberbullying behavior and make the online community safer and more welcoming for students. This work suggests the high importance of advanced machine learning approaches to real-world social problems and contributes to the creation of greater digital well-being in university students’ communities. By employing CBNet, institutions can take proactive measures to mitigate the harmful effects of cyberbullying and cultivate a positive online culture conducive to student success and flourishing.
Effects of dietary Trollius chinensis Bunge residue on performance, meat quality, antioxidant capacity, intestinal health, and cecal microbiota in weaned rabbits
Authors: Deng Lingcong , Yu Jiayu , Dong Yu , Han Kailong , Zhang Xue , Li Jiani , Yang Xue , Fei Dongliang , Han Xibin , Ma Mingxiao , Bai Jieying 
Published: January 2025

Abstract

The present study aimed to investigate the effects of Trollius chinensis Bunge residues (TCBR) on growth, meat quality, antioxidant capacity, intestinal healthy and cecal microbiota in weaned rabbits. In total, 48 30-day-old rabbits were randomly allocated into 4 groups, with 12 replicates per group. Four diets were formulated with graded levels of TCBR: 2.0%, 4.0%, and 6.0% represented as TCBR2, TCBR4, and TCBR6 groups alongside a control group without TCBR. The results showed that TCBR2 significantly alleviated adverse clinical manifestations in weaned rabbits and improved survival rate, growth performance, and meat quality. while reducing the feed conversion ratio compared with the Mock group. TCBR2 also enhanced carcass yield, semi-eviscerated carcass yield, liver index, and liver antioxidant capacity, and increased jejunal villus height and villus/crypt ratio compared with that in the Mock group, whereas no differences were observed between the TCBR4 and TCBR6 groups. Notably, 16S RNA analysis revealed that Bacteroidota levels were significantly elevated in the TCBR2 groups, with Akkermansia, Clostridium, and Succiniclasticum also upregulated in the TCBR2 group. Furthermore, TCBR2 significantly increased the expression levels of occludin and ZO-1 in jejunal tissue. In conclusion, TCBR2 supplementation improved growth performance and attenuated adverse clinical symptoms in rabbits.
The longitudinal interplay between loneliness and depressive symptoms during late childhood: Cross-lagged panel network analyses
Authors: Grygiel Paweł , Opozda-Suder Sylwia , Dolata Roman 
Published: January 2025

Abstract

This study uses a cross-lagged panel network model with a sample of 4,333 children (Mage = 11.06, SD = 0.73; 50.8% girls at T1) to examine the relationship between loneliness and depressive symptoms over a two-year period. The cross-sectional network shows that loneliness is strongly associated with sadness, perceived parental pressure, and boredom. The longitudinal network suggests: (1) a reciprocal link between loneliness and both sadness and parental pressure; (2) a forward effect of loneliness on anxiety and being busy; (3) the loneliness-reducing effect of prior happiness and loneliness-increasing effect of boredom. This research highlights the complex interplay of emotions in adolescents, emphasizing the need for targeted interventions to address the interrelated emotional and social issues associated with the risk of loneliness and depression.
Identifying the association between Physical Activity and HCV infection status: An observational study and Mendelian randomization analysis
Authors: Lei Liangchen , Ouyang Chen , Liu Pengpeng , Liu Quanyan 
Published: January 2025

Abstract

Purpose
To investigate the association and causality between physical activity and hepatitis C virus (HCV) infection.
Methods
In this cross-sectional study, we conducted a bidirectional two-sample Mendelian Randomization (MR) analysis using data from the GWAS database. The analytic population was divided into three categories based on hepatitis C virus infection outcomes, and statistical differences were analyzed with covariates. Additionally, Restricted Cubic Spline (RCS) analysis was applied to examine the nonlinear relationship between physical exercise and hepatitis C virus infection. Instrumental variables were selected with a threshold of P < 5*10⁻⁸, and the causal relationships were assessed using IVW, MR-Egger, Weighted Median, Weighted Mode, and Simple Mode methods. Cochran's Q test was used to assess and exclude data heterogeneity.
Results
In the population data analysis, the moderate-to-vigorous work (MVW) variable showed a significant association with HCV infection (p = 0.006). MVW demonstrated a positive association with HCV infection (OR = 2.46, 95% CI = 1.02–5.92). RCS analysis indicated that the risk of HCV infection significantly increased when MVW exceeded 810 minutes per week. MR analysis indicated that MVW had a unidirectional effect on HCV infection (IVW model: OR = 1.366, 95% CI: 1.121–1.663, p = 0.002), and heterogeneity was excluded from the analysis.
Conclusions
In the context of HCV infection, the primary factor influencing risk is not the duration of physical activity, but the type. High-intensity physical activity significantly elevates the risk of HCV infection. It may be prudent to manage work hours responsibly to minimize physical strain.