bluuebunny/crossref_metadata_2025_split huggingface dataset:
Radiomics for preoperative prediction of early recurrence in hepatocellular carcinoma: a meta-analysis
Authors: Tian Huan , Xie Yong , Wang Zhiqun 
Published: June 2023

Background/ObjectiveEarly recurrence (ER) affects the long-term survival prognosis of patients with hepatocellular carcinoma (HCC). Many previous studies have utilized CT/MRI-based radiomics to predict ER after radical treatment, achieving high predictive value. However, the diagnostic performance of radiomics for the preoperative identification of ER remains uncertain. Therefore, we aimed to perform a meta-analysis to investigate the predictive performance of radiomics for ER in HCC.MethodsA systematic literature search was conducted in PubMed, Web of Science (including MEDLINE), EMBASE and the Cochrane Central Register of Controlled Trials to identify studies that utilized radiomics methods to assess ER in HCC. Data were extracted and quality assessed for retrieved studies. Statistical analyses included pooled data, tests for heterogeneity, and publication bias. Meta-regression and subgroup analyses were performed to investigate potential sources of heterogeneity.ResultsThe analysis included fifteen studies involving 3,281 patients focusing on preoperative CT/MRI-based radiomics for the prediction of ER in HCC. The combined sensitivity, specificity, and area under the curve (AUC) of the receiver operating characteristic were 75% (95% CI: 65-82), 78% (95% CI: 68-85), and 83% (95% CI: 79-86), respectively. The combined positive likelihood ratio, negative likelihood ratio, diagnostic score, and diagnostic odds ratio were 3.35 (95% CI: 2.41-4.65), 0.33 (95% CI: 0.25-0.43), 2.33 (95% CI: 1.91-2.75), and 10.29 (95% CI: 6.79-15.61), respectively. Substantial heterogeneity was observed among the studies (I²=99%; 95% CI: 99-100). Meta-regression showed imaging equipment contributed to the heterogeneity of specificity in subgroup analysis (P= 0.03).ConclusionPreoperative CT/MRI-based radiomics appears to be a promising and non-invasive predictive approach with moderate ER recognition performance.
Inflammation-related research within the field of bladder cancer: a bibliometric analysis
Authors: Deng Zhixuan , Tang Ning , Xiong Wanyan , Lei Xu , Zhang Tengfei , Yang Ning 
Published: June 2023

BackgroundIn recent years, the link between inflammation and bladder cancer(BC) has received much attention. However, there were no relevant bibliometric studies to analyze the inflammation-related research within this field of BC.MethodsWe selected Web of Science Core Collection (WOSCC) as the data source to obtain articles and reviews on inflammation-related research within te field of BC from WOSCC’s inception to October 10, 2022. The collected data were meticulously and manually screened, after which we used VOSviewer, CiteSpace, Biblioshiny and an online analysis platform (https://bibliometric.com/) to perform bibliometric analysis on the data and visualize the results.ResultsA total of 4301 papers related to inflammation-related research within this field of BC were included in this study.The number of publications has steadily increased over the last decades (R²=0.9021). The top contributing country was the United States, O’Donnell, Michael A was the most published authors, the leading contributing institution was the University of Texas, and the leading contributing journal was JOURNAL OF UROLOGY. The keywords co-occurrence analysis indicated that “immunotherapy,” “inflammation-related biomarkers,” and “tumor microenvironment” were the hot spots and frontiers of research in this field.ConclusionThis study clarifies the contribution of countries, institutions, authors, and journals in inflammation-related research within this field of BC through a bibliometric approach and identifies research hotspots and frontiers in the field. Notably, these findings can help researchers to understand more clearly the relationship between inflammation and BC.
High resolution mapping of QTLs for fruit color and firmness in Amrapali/Sensation mango hybrids
Authors: Srivastav Manish , Radadiya Nidhi , Ramachandra Sridhar , Jayaswal Pawan Kumar , Singh Nisha , Singh Sangeeta , Mahato Ajay Kumar , Tandon Gitanjali , Gupta Ankit , Devi Rajni , Subrayagowda Sreekanth Halli , Kumar Gulshan , Prakash Pragya , Singh Shivani , Sharma Nimisha , Nagaraja A. , Kar Abhijit , Rudra Shalini Gaur , Sethi Shruti , Jaiswal Sarika , Iquebal Mir Asif , Singh Rakesh , Singh Sanjay Kumar , Singh Nagendra Kumar 
Published: June 2023

IntroductionMango (Mangifera indica L.), acclaimed as the ‘king of fruits’ in the tropical world, has historical, religious, and economic values. It is grown commercially in more than 100 countries, and fresh mango world trade accounts for ~3,200 million US dollars for the year 2020. Mango is widely cultivated in sub-tropical and tropical regions of the world, with India, China, and Thailand being the top three producers. Mango fruit is adored for its taste, color, flavor, and aroma. Fruit color and firmness are important fruit quality traits for consumer acceptance, but their genetics is poorly understood.MethodsFor mapping of fruit color and firmness, mango varieties Amrapali and Sensation, having contrasting fruit quality traits, were crossed for the development of a mapping population. Ninety-two bi-parental progenies obtained from this cross were used for the construction of a high-density linkage map and identification of QTLs. Genotyping was carried out using an 80K SNP chip array.Results and discussionInitially, we constructed two high-density linkage maps based on the segregation of female and male parents. A female map with 3,213 SNPs and male map with 1,781 SNPs were distributed on 20 linkages groups covering map lengths of 2,844.39 and 2,684.22cM, respectively. Finally, the integrated map was constructed comprised of 4,361 SNP markers distributed on 20 linkage groups, which consisted of the chromosome haploid number in Mangifera indica (n =20). The integrated genetic map covered the entire genome of Mangifera indica cv. Dashehari, with a total genetic distance of 2,982.75 cM and an average distance between markers of 0.68 cM. The length of LGs varied from 85.78 to 218.28 cM, with a mean size of 149.14 cM. Phenotyping for fruit color and firmness traits was done for two consecutive seasons. We identified important consistent QTLs for 12 out of 20 traits, with integrated genetic linkages having significant LOD scores in at least one season. Important consistent QTLs for fruit peel color are located at Chr 3 and 18, and firmness on Chr 11 and 20. The QTLs mapped in this study would be useful in the marker-assisted breeding of mango for improved efficiency.
Real-time on-site detection of the three ‘Candidatus Liberibacter’ species associated with HLB disease: a rapid and validated method
Authors: Morán Félix , Herrero-Cervera Mario , Carvajal-Rojas Sofía , Marco-Noales Ester 
Published: June 2023

Huanglongbing (HLB) is a devastating disease that affects all commercial citrus species worldwide. The disease is associated with bacteria of three species of the genus ‘Candidatus Liberibacter’ transmitted by psyllid vectors. To date, HLB has no cure, so preventing its introduction into HLB-free areas is the best strategy to control its spread. For that, the use of accurate, sensitive, specific, and reliable detection methods is critical for good integrated management of this serious disease. This study presents a new real-time recombinase polymerase amplification (RPA) protocol able to detect the three ‘Ca. Liberibacter’ species associated with HLB in both plant and insect samples, validated according to European and Mediterranean Plant Protection Organization (EPPO) guidelines and tested on 365 samples from nine different geographic origins. This new protocol does not require nucleic acid purification or specialized equipment, making it ideal to be used under field conditions. It is based on specific primers and probe targeting a region of fusA gene, which shows a specificity of 94%–100%, both in silico and in vitro, for the ‘Ca. Liberibacter’ species associated with HLB. The analytical sensitivity of the new protocol is excellent, with a reliable detection limit in the order of 101 copies per microliter in HLB-infected plant and insect material. The repeatability and reproducibility of the new methods showed consistent results. Diagnostic parameters of the new RPA protocol were calculated and compared with the gold standard technique, a quantitative real-time PCR, in both crude extracts of citrus plants and insect vectors. The agreement between the two techniques was almost perfect according to the estimated Cohen’s kappa index, with a diagnostic sensitivity and specificity of 83.89% and 100%, respectively, and a relative accuracy of 91.59%. Moreover, the results are obtained in less than 35 min. All these results indicate the potential of this new RPA protocol to be implemented as a reliable on-site detection kit for HLB due to its simplicity, speed, and portability.
The mediating roles of psychological resilience and frustration tolerance in the relationship between coping styles and mood states of high-level basketball referees
Authors: Wang Qiulin , Wang Wei , Huang Huanhuan , Wan Binghui 
Published: June 2023

ObjectiveIn order to promote the development of high-quality professional basketball referees in China, we explored the relationship between their coping styles and mood states during the game and assessed the contributions of psychological resilience and frustration tolerance to this relationship.MethodsA total of 364 national and international male and female basketball referees were recruited and surveyed via the online questionnaire platform “Questionnaire Star”. All participants signed an informed consent form and completed the questionnaire. Common method bias test and Pearson correlation tests were used to analyze the study indicators, and the theoretical model for this study was validated using Process plug-in developed by Hayes.ResultsThe results of the study showed that the coping style of the referees significantly predicted their psychological resilience, frustration tolerance, and mood state. Coping style enhanced psychological resilience (β = −0.30) and frustration tolerance (β = 0.38) and improved the mood states (β = 0.33) of the referees. In addition, coping style directly predicted mood state but also indirectly predict mood state through the intermediary variables of psychological resilience (β = 0.14) and frustration tolerance (β = 0.11), and the mediating effects accounted for 24.20 and 18.90% of the total effect, with psychological resilience playing a greater role than frustration tolerance. (β: standardized regression coefficient).ConclusionThese findings suggest that when training high-level basketball referees, increasing the psychological indicators related to the coping styles and psychological resilience of high-level basketball referees can avoid their large emotional fluctuations and improve their accuracy in judging when facing unexpected events on the court.
Psychometric properties of the Sport Courage Scale for Chinese athletes
Authors: Gao Shenmao , Guo Zeyou , Zhang Renfang , Jin Junze , Dou Guangbo 
Published: June 2023

ObjectiveTo revise Sport Courage Scale (SCS) suitable for Chinese athletes.MethodsSix hundred and eighty three athletes were selected for verification factor analysis, correlation analysis, reliability analysis, and independent sample t-test using the method of random sampling of the entire group.ResultsConfirmatory factor analysis model showed that model 1 (25 items) failed to fit the data; while model 2 (20 items) was finally accepted with its five-factor model. The factor structure consists of 5 dimensions (χ2/df = 2.262;CFI = 0.969;TLI = 0.963; RMSEA = 0.043; SRMR = 0.044). Cronbach’s α of the final version of SCS was 0.845, and the corrected correlation coefficient between the items and the total score of the scale was between 0.352 and 0.788.ConclusionRevised SCS has good reliability and validity and can be used as a measurement tool for the sports courage of athletes in China.
Predicting depressive symptom by cardiometabolic indicators in mid-aged and older adults in China: a population-based cross-sectional study
Authors: Wang Ying , Zhang Xiaoyun , Li Yuqing , Gui Jiaofeng , Mei Yujin , Yang Xue , Liu Haiyang , Guo Lei-lei , Li Jinlong , Lei Yunxiao , Li Xiaoping , Sun Lu , Yang Liu , Yuan Ting , Wang Congzhi , Zhang Dongmei , Li Jing , Liu Mingming , Hua Ying , Zhang Lin 
Published: June 2023

ObjectiveDepressive symptom is a serious mental illness often accompanied by physical and emotional problems. The prevalence of depressive symptom in older adults has become an increasingly important public health priority. Our study used cardiometabolic indicators to predict depressive symptom in middle-aged and older adults in China.MethodsThe data came from the China Health and Retirement Longitudinal Study 2011 (CHARLS2011), which was a cross-sectional study. The analytic sample included 8,942 participants aged 45 years or above. The study evaluated the relationship between cardiometabolic indicators and depression by measuring 13 indicators, including body mass index (BMI), waist circumference, waist-height ratio (WHtR), conicity index, visceral adiposity index (VAI), Chinese visceral adiposity index (CVAI), lipid accumulation product (LAP), a body shape index (ABSI), body roundness index (BRI), triglyceride glucose index (TyG-index) and its correlation index (TyG-BMI, TyG-waist circumference, TyG-WHtR). Binary logistic regression analysis was used to examine the association between thirteen cardiometabolic indicators and depressive symptom. In addition, the receiver operating characteristic (ROC) curve analysis and area under curve (AUC) were used to evaluate the predictive anthropometric index and to determine the optimum cut-off value.ResultsThe study included 8,942 participants, of whom 4,146 (46.37%) and 4,796 (53.63%) were male and female. The prevalence of depressive symptom in mid-aged and older adults in China was 41.12% in males and 55.05% in females. The results revealed that BMI [AUC = 0.440, 95%CI: 0.422–0.457], waist circumference [AUC = 0.443, 95%CI: 0.425–0.460], WHtR [AUC = 0.459, 95%CI: 0.441–0.476], LAP [AUC = 0.455, 95%CI: 0.437–0.472], BRI [AUC = 0.459, 95%CI: 0.441–0.476], CVAI [AUC = 0.449, 95%CI: 0.432–0.467], TyG-BMI [AUC = 0.447, 95%CI: 0.429–0.465], and TyG-waist circumference [AUC =0.452, 95%CI: 0.434–0.470] were weak predictors of depressive symptom (p &lt; 0.05) in males. In females, BMI [AUC = 0.470, 95%CI: 0.453–0.486], LAP [AUC = 0.484, 95%CI: 0.467–0.500], TyG-BMI [AUC = 0.470, 95%CI: 0.454–0.487], and TyG-waist circumference [AUC =0.481, 95%CI: 0.465–0.498] were weak predictors of depressive symptom (p &lt; 0.05). On the other side, VAI, ABSI, conicity index and TyG index could not predict depressive symptom in middle-aged and older adults.ConclusionMost cardiometabolic indicators have important value in predicting depressive symptom. Our results can provide measures for the early identification of depressive symptom in middle-aged and older adults in China to reduce the prevalence of depressive symptom and improve health.
A Second-Order Time Discretization for Second Kind Volterra Integral Equations with Non-Smooth Solutions
Authors: Zhou Boya , Cheng Xiujun 
Published: June 2023

In this paper, a novel second-order method based on a change of variable and the symmetrical and repeated quadrature formula is presented for numerical solving second kind Volterra integral equations with non-smooth solutions. Applying the discrete Grönwall inequality with weak singularity, the convergence order O(N−2) in L∞ norm is proved, where N refers to the number of time steps. Numerical results are conducted to verify the efficiency and accuracy of the method.
Separate Hydrolysis and Fermentation of Kitchen Waste Residues Using Multi-Enzyme Preparation from Aspergillus niger P-19 for the Production of Biofertilizer Formulations
Authors: Sharma Apurav , Dogra Sakshi , Thakur Bishakha , Yadav Jyoti , Soni Raman , Soni Sanjeev Kumar 
Published: June 2023

This study addresses the management of kitchen waste by transforming it into biofertilizer formulations, utilizing an effective, in-house-developed multi-enzyme preparation. An approach consisting of separate hydrolysis and fermentation bioprocessing processes was used, employing a multi-enzyme preparation from Aspergillus niger P-19 to separately hydrolyze kitchen waste, followed by the fermentation of the hydrolysate for the growth of Klebsiella pneumoniae AP-407, which has biofertilizer traits. This has led to the simultaneous generation of liquid as well as carrier-based biofertilizer formulations with viable cell counts of 3.00 × 1012 CFU/mL and 3.00 × 1012 CFU/g, respectively. Both biofertilizer formulations significantly enhanced the morphometric characteristics and leaf chlorophyll contents of Tagetes erecta, in addition to enriching the soil with essential nutrients. The current study adopted a novel processing technology for the manufacturing of both carrier and liquid biofertilizers, adopting a zero-waste approach for the management of kitchen waste.
Besaran dan Orientasi Bukaan Pencahayaan Alami Rumah untuk Kenyamanan Beraktivitas Selama Pandemi
Authors: Muntakilah Silmi Novia , Rusyda Hana Faza Surya 
Published: June 2023

Pencahayaan alami merupakan indikator penting pada perancangan bangunan. Saat ini banyak kegiatan yang dirumahkan sehingga penting untuk ruang dalam dapat tetap digunakan sebagai tempat beraktivitas dengan nyaman. Cahaya matahari yang masuk ke dalam ruang secara optimal menciptakan sistem pencahayaan alami yang baik, namun karenanya dapat terjadi peningkatan suhu yang tidak diinginkan. Penelitian ini bertujuan untuk mengetahui efektivitas cahaya alami pada objek studi rumah tinggal. Metode kuantitatif dilakukan dengan pengumpulan data dari literatur dan observasi pada hunian di kawasan Buah Batu, Bandung yang masing-masing bukaan dihitung efektivitas pencahayaan alaminya terhadap ruang dalam. Pada hasil penelitian ini diperoleh efektivitas pencahayaan alami di ruang keluarga sebesar 517.6 lux dengan orientasi menghadap utara, kamar tidur utama 445.6 lux menghadap utara, dan kamar tidur anak 280 lux dengan orientasi menghadap barat yang tingkat pencahayaan alaminya sudah sesuai standar dari SNI pada ruang tamu dan kamar tidur dengan minimum 150 hingga 250 lux. Dengan hasil dari objek studi di penelitian ini diharapkan faktor lubang cahaya efektif dan orientasi pada perancangan rumah tinggal lebih dipertimbangkan sehingga kenyamanan beraktivitas penghuni dapat tercapai.

Kata Kunci: rumah tinggal, pencahayaan alami, kenyamanan ruang, aktivitas pandemi
Peran Warna Desain Interior terhadap Perasaan Tenang Pengunjung SPA “Martha Tilaar”
Authors: Monica Agnes , Darmayanti Tessa Eka 
Published: June 2023

Desain Interior pada ruang Spa saat ini menjadi perhatian khusus dalam meningkatkan kualitasnya sebagai pendukung pemulihan psikologis pengunjung guna memberikan ruangan yang nyaman dan tenang salah satunya pertimbangan terhadap warna ruang. Warna merupakan elemen penting interior karena Lapisan cat dapat mengubah interior secara dramatis, menyamarkan masalah desain, bahkan bisa mengubah keadaan psikologis individu yang berada di dalamnya dan jika orang tersebut lelah, warna bisa “menyamarkan”nya. Tujuan dari penelitian ini untuk mengetahui peran warna terhadap ruangan Spa dalam efek psikologis yang dirasakan pengunjung. Penelitian ini menggunakan metode kualitatif dengan studi literatur dan wawancara berkaitan dengan topik pembahasan. Hasil penelitian mengenai warn aini memperlihatkan bahwa penggunaan atau penetapan warna tunggal dan perpaduan warna kontras memberikan kesan dan dampak yang berbeda pada psikologis individu dan suasana ruang. Warna tunggal dapat memberikan ketenangan sedangkan warna kontras memberikan efek gairah yang kurang tepat diimplementasikan pada fasilitas Spa. Selain itu, diharapkan juga dapat menjadi referensi perancangan ruang Spa dengan mempertimbangkan warna ruang dan efek psikologisnya terhadap pengunjung Spa.

Kata Kunci: desain interior, pengunjung spa, psikologi warna.
Tinjauan Desain Furniture dan Suasana Pada Kafé Wongkis 76
Authors: Lestari Siti Indah , Salma Afifah 
Published: June 2023

The cafe is a place that is very popular with many people, from young people to old people. Cafe is usually visited as a place to eat and drink with a relaxed atmosphere. But along with the development of the times more and more various types of cafes are present, this place is visited not only to eat and drink in a relaxed atmosphere but some people come to the cafe for a business job, family gatherings, and millennials who usually just want to get an additional collection of aesthetic photo spots. In this study, I conducted a review of the wongkis 76 cafe located on Jl. Telaga Sari, Tanjung Morawa District, Deli Serdang Regency, North Sumatra. The method I use in this research is a descriptive research method with a qualitative method approach. The data was collected from a field observation by conducting a survey directly to the location that I reviewed, namely wongkis 76 Café. From the results of the survey, I found several problems that exist in Wongk is 76 cafe, these problems include the narrow cafe space in several spaces for walking and one of them is on the stairs from the 1st floor to the 2nd floor. Some of the furniture the chairs in this cafe are not ergonomic and the size is not in accordance with the anthropometry of the human body, where the ergonomic shape of a chair greatly affects the comfort of the visitors. The purpose of this research I did to find out the problems that exist in wongkis 76 Cafe and find solutions to these problems.
PREFERENSI DESAIN INTERIOR KANTOR MODERN BERDASARKAN FUNGSI ELEMEN RUANG BAGI GENERASI MILENIAL
Authors: Kerdiati Ni Luh Kadek Resi , Waisnawa I Made Jayadi , Wasista I Putu Udiyana 
Published: June 2023

ABSTRAK
Generasi milenial adalah generasi yang lahir antara tahun 1989 – 1995 dan kedepannya generasi inilah yang akan mendominasi dunia kerja. Berbeda dengan generasi sebelumnya, generasi milenial identik dengan perkembangan teknologi, menyukai keterbukaan dan kebebasan, memiliki berbaSgai ide kreatif yang siap dituangkan kapan saja, percaya diri, serta menyukai hal yang praktis.. Berdasarkan hal tersebut, perlu dilakukan penyesuaian terhadap desain interior kantor untuk dapat meningkatkan produktifitas penggunanya, yang dalam hal ini adalah generasi milenial. Penelitian dilakukan menggunakan metode kualitatif, melalui studi dokumen dan selanjutnya seluruh hasil analisis dijabarkan secara deskriptif. Berdasarkan analisis data yang ada diketahui bahwa konsep tata ruang yang cocok digunakan untuk kantor milenial adalag tata ruang gabungan (perpaduan tata ruang terbuka dan tertutup); menyediakan beberapa ospi jenis furniture; penerapan warna yang sesuai jenis pekerjaan; pemilihan unsur dekoratif yang tidak memakan tempat dan low maintenance; pepaduan pencahayaan serta penghawaan alami dan buatan; meredam suara bising dengan material yang tepat; serta menyediakan fasilitas pendukung tambahan. Melalui penelitian ini diharapkan dapat memberikan pengetahuan untuk pengembangan desain kantor yang sesuai dengan generasi penggunanya, sehingga dapat meningkatkan produktifitas kerja. Selain itu juga diharapkan dapat menjadi sumber referensi untuk penelitian selanjutnya.

Kata Kunci: Interior, Kantor Modern, Generasi Milenial
صورة النكبة في الشعر الفلسطيني شعراء المنفى إنموذجا [ دراسة نحليلية ]
Authors: أ.م.د . لؤي شهاب محمود  
Published: June 2023

ان النكبة والتراجيديا الفلسطينية كانت وستظل نبعا لا يجف ومعينا لا ينضب في
الشعر الفلسطيني الثوري الملتزم اذ جعلت من هذا الشعر شعرا عروبيا وقوميا وطبقيا
ووظيفيا مقاوما منحاز للفقراء وابناء الشوارع والارصفة والمخيمات ورفضا لواقع التشرد
والبؤس الا انه خلق جو اعتملت فيه الثورة والمقاومة والاحتجاج والرفض في النفوس
المعذبة فكان شعراء فلسطين الامل القادر على تضميد الجراح بكلماتهم وشعرهم.