bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gut-Skin axis and healthy skin: a systematic review
Authors: Liedtke Fernanda Soubhia 
Published: June 2023

Introduction: The skin has a multifactorial aging process, both by intrinsic and extrinsic predictors. Skin diseases contributed almost 2.0% to the global burden of 308 diseases and injuries in recent years. The role of the gut microbiota (GM) in human aging is important. GM directly affects aging through the gastrointestinal system. The microbial impact on the skin is still not fully understood. Objective: The present study analyzed the major scientific evidence on the relationship between gut microbiota and the skin, emphasizing the importance of intestinal health for aesthetically healthy skin. Methods: The systematic review rules of the PRISMA Platform were followed. The research was carried out from February to May 2023 in Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: A total of 137 articles were found. A total of 47 articles were fully evaluated and 27 were included and developed in the present systematic review study. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 30 studies at high risk of bias and 13 studies that did not meet the GRADE. It was concluded that current scientific evidence reveals the existence of an important Skin-GM axis, highlighting the management of dermatoses through probiotics and prebiotics, as well as lifestyle changes. To establish aesthetically healthy skin, it is imperative to manipulate the gut microbiota to achieve balance. Thus, treatments that elevate or repair a bowel are essential as adjunctive therapy in the management of inflammatory skin diseases and may contribute to the effectiveness of standard dermal therapy.
Herstelrecht als straf
Authors: Gade Christian 
Published: June 2023

Restorative justice as punishment. A paradigm shift within the restorative justice movement?
Restorative justice has frequently been presented as a new criminal justice paradigm, and as something that is radically different from punishment. The author argues that this ‘oppositioning’ against criminal law is problematic, partly because the restorative justice movement remains too much on the margins of the criminal justice system. Restorative justice could reasonably be more widely adopted as a new form of punishment, which could potentially increase the use of restorative justice for the benefit of victims, offenders and society at large.
Is een nieuw strafparadigma bevorderlijk voor het herstelrecht?
Authors: Chapman Tim 
Published: June 2023

Is a new punishment paradigm conducive to restorative justice?
The author opposes Gade’s proposal and warns against a potential loss of authentic restorative justice solutions. Restorative justice should not be understood as a punishment practice, the restorative justice dialogue is valuable in itself. Moreover, the author wonders whether the focus on results advocated by Gade is really desirable.
Institucionalização das práticas de gestão e coordenação do cuidado na Atenção Primária à Saúde na percepção de gestores e enfermeiros
Authors: Gurgel Júnior Francisco Freitas , Jorge Maria Salete Bessa , Conde Lucia de Oliveira , Vergara Clarice Maria Araújo Chagas , Sampaio Helena Alves de Carvalho , Araújo Perpétua Alexsandra 
Published: June 2023

Introdução: Gestão e coordenação do cuidado significam estabelecer conexões de modo a alcançar o objetivo maior de prover/atender às necessidades e preferências dos usuários na oferta de cuidados em saúde, com elevado valor, qualidade e continuidade. Objetivo: Analisar a institucionalização das práticas de atenção a gestão e coordenação do cuidado nos serviços de saúde da Atenção Primária à Saúde. Metodologia: Utilizou-se a Análise Institucional, na sua vertente socioanalítica, como referencial teórico-metodológico. Como ferramentas fez-se uso da observação participante, diário de pesquisa, entrevista e rodas de conversa e a realização de grupos de restituição com os enfermeiros e gestores do sistema de saúde local. Resultados e Discussão: Os resultados mostraram que a resistência do sujeito à mudança implica obstáculo para o desenvolvimento e a consolidação das práticas de atenção na gestão e coordenação do cuidado. Destarte, há uma responsabilidade coletiva dos profissionais, entretanto ocorre em algumas vezes a falta de planejamento e/ou engajamento da equipe. Conclusão: Uma política de gestão que opere com base por resultados, pode oprimir e desestimular o potencial dos coletivos bem como o desenvolvimento e a criação de novas alternativas diante dos impasses vivenciados.
Assessment of Small-Scale Microplastics Abundance and Characterization in Urban River: A Case Study in Metro River, Indonesia
Authors: Haribowo Riyanto , Rubiantoro Prasetyo , Fadhilah Arriel , Alovy Petra Denindya Zefanya , Ayu Kristanti Yunike , Rismiati Wahyu , Aulia Arsal Muhammad 
Published: June 2023

Microplastic pollution is a pressing environmental concern with detrimental effects on aquatic ecosystems and human health. This study aimed to investigate microplastic contamination in a rapidly urbanizing area along a river and to examine the spatial distribution of microplastic abundance across the study area based on land use type. Seven sampling points were selected along the study site and microplastic samples were extracted using density separation and wet peroxidation (WPO) methods. The characteristics of the microplastic particles, including size, color, shape, and abundance, were analyzed to understand their properties. The results indicated that the microplastic abundance values ranged from 28.33 to 133.00 particles/liter, with an average of 73.55 particles/liter. Small microplastic particles (SMP), with sizes ranging from 1 μm to 1 mm, along with fragment shapes, and clear colors were predominant in the study area. A generalized additive model was utilized to assess the relationship between land use and microplastic abundance. The model demonstrated a significant influence of built-up areas on the presence of microplastics (p-value < 0.05), with an r2 value of 0.76. Residential areas near the river were identified as the likely primary sources of the microplastics.
Bitki ekstraktlarının marine hamsinin depolama stabilitesi üzerine etkisi
Authors: YEŞİLSU Ahmet Faruk , ERBAY Esen Alp , DAĞTEKİN Büket Buşra 
Published: June 2023

Amaç: Bu çalışmada, doğal bitki özleri olarak antimikrobiyal ve antioksidan özellikleri ile bilinen kekik ve biberiye tozu ekstraktlarının; soğukta muhafaza edilen marine hamsilerin kimyasal, fiziksel ve mikrobiyolojik özelliklerine etkilerinin belirlenmesi amaçlanmıştır.
Materyal ve yöntem: Hamsi filetoları sodyum klorür NaCl (%10) ve asetik asit (%4) ile marine edilmiştir. 4ºC’de 6 ay süre ile depolama esnasında içinde bekletildiği bitkisel yağa ilave edilen kekik (750 ppm) ve biberiye (750 ppm) ekstraktlarının, marine edilmiş hamsilerin depolama stabilitesi ve mikrobiyolojik değişimleri üzerine etkisi incelenerek duyusal analizleri gerçekleştirilmiştir.
Bulgular ve sonuç: Çalışma sonunda kekik ve biberiye ilave edilen grupların L* değerleri sırasıyla 56,90±0,18 ve 57,28±0,51 olarak tespit edilmiştir. Grupların pH, asitlik ve tuz değerlerinin depolama boyunca birbirine benzer sonuçlar gösterdiği belirlenmiştir. Depolama sonunda peroksit değerleri kekik grubunda 13,68, biberiye grubunda 15,19; Tiyobarbitürik Asit (TBA) değerleri ise sırasıyla 4,59 ve 4,49 olarak tespit edilmiştir. Depolamanın 180. gününde analizi yapılan örneklerdeki histamin miktarının kekik grubunda 8,90 ppm ve biberiye grubunda ise 8,33 ppm ile kabul edilebilir limitlerin içerisinde olduğu tespit edilmiştir. Bununla birlikte örneklerin hiçbirinde toplam aerobik mezofilik bakteri, laktik asit bakterisi, psikrotrofik bakteri ve maya-küf gelişiminin 2001/24307 nolu Su Ürünleri Yönetmeliği ile belirlenen sınırlar içerisinde kaldığı gözlenmiştir. Duyusal özellikler açısından tat ve lezzet puanlarına bakıldığında 60. günde kekik ilave edilen grubun biberiye ilave edilen gruptan daha yüksek puanlar aldığı belirlenmiştir. Sonuç olarak kekik ve biberiye ekstraktlarının bazı kalite parametreleri ve belirli depolama zamanlarında birbirine üstünlük sağladıkları, genel olarak ise her iki ekstraktın da hamsi marinasyonunda depolama stabilitesini artırmada etkin oldukları gözlenmiştir.
Analysis of Macrophage Migration Inhibitory Factor Genotype in Hemophilia a Patients
Authors: Hadi Murtadha A. , Ibrahim Wijdan N. , Hassan Meaad K. 
Published: June 2023

Background:
Hemophilia A, an X-linked bleeding disorder, is caused by a complete or partial deficiency in factor VIII. Multiple factors engage in the development and progression of bleeding episodes in hemophilia patients, especially arthropathy.

Objectives:
Detection of macrophage migration inhibitory factor (MIF)-173 G/C polymorphism in people with hemophilia A (PWH) and the possible associations between the type of MIF gene polymorphism and selected disease-related variables.

Patients and methods:
This case–control study included 95 male patients with hemophilia A and 95 non-hemophiliac subjects, all aged from 2 months to 63 years.
An allele-specific polymerase chain reaction (AS-PCR) with a multiplex technique was used to detect MIF polymorphisms.

Results:
A significantly higher frequency of GG polymorphism was reported in the control group (81, 85.3%) compared to PWH (64, 67.4%), while a significantly higher frequency of GC polymorphism was found in PWH (21, 22.1%) than that in healthy subjects (10, 10.5%), P < 0.05.
The G allele polymorphism was detected in 90.0% of the control group compared to 78.4% of PWH (149 subjects), while the C allele frequency was higher in PWH (41, 21.6%) compared to that in healthy individuals (18, 10.0%), P < 0.05.
The frequencies of varied MIF-173 polymorphisms did not show significant differences among patients with different clinical presentations or in relation to presence of inhibitors, P > 0.05.

Conclusions:
MIF-173 GC polymorphism is seen in PWH more than that in healthy individuals. Further studies are required to detect additional SNPs through sequencing of the MIF gene and to detect MIF serum levels during bleeding episodes.
PENGEMBANGAN MEDIA PEMBELAJARAN PADA MATERI TRANSFORMASI DENGAN BERBANTUAN I-SPRING DENGAN PENDEKATAN ETNOMATEMATIKA BERBASIS ANDROID
Authors: Ratnaningsih Nani , Nuradriani Meti , Nurazizah Icha Sofi 
Published: June 2023

Penelitian ini bertujuan untuk menghasilkan media pembelajaran matematika berbasis android untuk siswa SMP/MTs dengan melibatkan pakar pada proses pengembangan dan penilaian produknya. Metode: Penelitian ini merupakan penelitian pengembangan (Research and Development). Prosedur pengembangan menggunakan model 4D, yaitu: define (analisis pengguna, kurikulum, dan bahan ajar), design (merancang produk dengan alat dan bahan), develop (penilaian dan revisi), dan disseminate (uji coba pada calon pengguna). Instrumenpenelitian ini adalah angket. Tim penilai produk terdiri: ahli media,ahli materi dan respon siswa kelas 9 SMP/Mts.Hasil penelitiannya menunjukan bahwa media pembelajaran matematika berbasis android melalui pendekatan etnomatematika memperoleh penilaian dari validator rata-rata menyebutkan sangat sesuai dan sesuai,dan respon atau tanggapan siswa SMP kelas 9 terhadap media pembelajaran matematika berbasis android melalui pendekatan etnomatematika memberikan respon penilaian yang sangat baik. Dengan demikian sesuai hasil penilaian dari ahli media,ahli materi dan respon siswa terhadap produk pengembangan media pembelajaran pada materi transformasi dengan menggunakan iSpring melalui pendekatan Etnomatematika berbasis android dalam penelitian ini dapat digunakan oleh siswa SMP/MTs.
The Effect of Conventional and Islamic Microfinance on Poverty Alleviation in Bangladesh
Authors: Uddin Nazim , Benabderrahmane Omar 
Published: June 2023

Our study evaluated and examined the availability of credit services and outreach as well as propose better effect microfinance services in Bangladesh. The establishment of MFIs in Bangladesh is the result of multiple initiatives by successive government authorities. More recently, microfinance has become a system to address the challenge of poverty, and the past decade has seen a remarkable contribution from MFIs in different parts of the world. Our study used a sample of 400 Islamic and conventional microfinance clients through a simple random sampling technique. In analysing the descriptive data statistics, Pearson Moment correlations, Multiple Regression Analysis (MRA) and parametric tests such as independent t-test and ANOVA were used.
The study concluded that the credit facilities are available and accessible in the microfinance institutions irrespective of gender, type of business engaged by the client and the community he/she belongs.
Determinants of Costs-Efficiency for Commercial Banks Operating in Algeria Econometric Study during the Period 2010 – 2016
Authors: Mohammed FOUDOU , Belkacem MIMOUNI , Achouak BENKADDOUR 
Published: June 2023

This study aims to reveal the cost-efficiency determinants of banks expressed at a profit margin rate for all commercial banks operating in Algeria during the period (2010 - 2016) using the Panel models.
Among the most important results reached are the presence of statistical significance between the profit margin rate and both of the cost of financing the bank, the cost of fixed capital for the bank and the size of the bank, which is consistent with the logic of economic theory, while creating insignificant statistical relationship between the profit margin rate and the cost of operating the bank, which is not Corresponds to the logic of economic theory. This result was explained by the lack of optimal utilization of operating resources and insufficient response to the qualification requirements imposed by the information revolution, which affects the work of banks. It was also reached that the structure of the chosen cost ratios (the ratio of the bank’s financing cost, the bank’s operating cost ratio, the fixed capital cost ratio and the size of the bank) explain 85.6% of the cost-efficiency changes of banks operating in Algeria represented by the profit margin index
Crowdfunding as an Innovative Mechanism for Financing Start-Ups– The Ninvesti and TwiizaPlatforms as a Model
Authors: Dabah Mohamed Ridha , Benbraika Abdelouahab 
Published: June 2023

This study aims to clarify the role of crowdfunding as a modern technique for financing startups, and in order to identify the importance of this technique; we reviewed both the conceptual framework of startups and crowdfunding with and to identify the platforms of Twiiza and Ninvesti.
The results of this study concluded that there are many financing difficulties that startups face in Algeria, which is why and this is why crowdfunding is considered one of the best financing alternatives on which we can count, but we see that this type of funding is still fairly recent in
Algeria, where it has not yet been found. The financial and entrepreneurial culture necessary for its development, and this manifests itself through the lack of crowdfunding platforms on the one hand, as well as the weakness observed in the activities of crowdfunding platforms on the other hand, and this is why Algeria must redouble its efforts to promote crowdfunding by benefiting from the experiences of leading countries in terms of financing and by benefiting from emerging institutions.
Rapid Onsite Evaluation for Specimen Adequacy and Triage of Breast Masses in a Low-Resource Setting
Authors: Kimambo Asteria H. , Vuhahula Edda A. , Philipo Godfrey S. , Mushi Beatrice P. , Mmbaga Elia J. , Van Loon Katherine , Ng Dianna L. 
Published: June 2023

Context.—
Rapid onsite evaluation (ROSE) is critical in determining sample adequacy and triaging cytology samples. Although fine-needle aspiration biopsy (FNAB) is the primary method of initial tissue sampling in Tanzania, ROSE is not practiced.

Objective.—
To investigate the performance of ROSE in determining cellular adequacy and providing preliminary diagnoses in breast FNAB in a low-resource setting.

Design.—
Patients with breast masses were recruited prospectively from the FNAB clinic at Muhimbili National Hospital. Each FNAB was evaluated by ROSE for overall specimen adequacy, cellularity, and preliminary diagnosis. The preliminary interpretation was compared to the final cytologic diagnosis and histologic diagnosis, when available.

Results.—
Fifty FNAB cases were evaluated, and all were adequate for diagnosis on ROSE and final interpretation. Overall percentage of agreement (OPA) between preliminary and final cytologic diagnosis was 84%, positive percentage of agreement (PPA) was 33%, and negative percentage of agreement (NPA) was 100% (κ = 0.4, P &lt; .001). Twenty-one cases had correlating surgical resections. OPA between preliminary cytologic and histologic diagnoses was 67%, PPA was 22%, and NPA was 100% (κ = 0.2, P = .09). OPA between final cytologic and histologic diagnoses was 95%, PPA was 89%, and NPA was 100% (κ = 0.9, P = &lt;.001).

Conclusions.—
False-positive rates of ROSE diagnoses for breast FNAB are low. While preliminary cytologic diagnoses had a high false-negative rate, final cytologic diagnoses had overall high concordance with histologic diagnoses. Therefore, the role of ROSE for preliminary diagnosis should be considered carefully in low-resource settings, and it may need to be paired with additional interventions to improve pathologic diagnosis.
Las nuevas territoriales de y en la pandemia: desigualdades y conflictos en tiempos de aislamiento en Buenos Aires
Authors: Di Virgilio María Mercedes , Perelman Mariano Daniel 
Published: June 2023

El presente artículo busca comprender el modo en el que la pandemia impactó en el espacio urbano porteño, reconfigurando usos públicos y privados, retroalimentando desigualdades preexistentes y produciendo nuevas. El trabajo está basado en dos trabajos de campo realizados en 2020 durante la pandemia en Buenos Aires así como el análisis de fuetes secundarias. A fin de dar cuenta de estos procesos en una clave situada, el artículo aborda la relación entre desigualdad, pandemia y crisis, da cuenta de las características y procesos históricos de la ciudad de Buenos Aires que permiten comprender la geografía y el impacto de la pandemia y se centra en algunas transformaciones ocurridas a partir de las transformaciones urbanas en la pandemia.
Penggunaan Dokumen Elektronik Sebagai Alat Bukti Oleh Hakim Dalam Pertimbangan Putusan Perkara Pornografi (Studi Putusan Nomor 16/PID SUS/2021/PN Kupang Dan Putusan Nomor 162/PID.SUS/2020/PN Kupang)
Authors: Sersan Sedau Karloswan , Masu Reny Rebeka , Tungga Ishak Alfred 
Published: June 2023

Tujuan penelitian ini adalah untuk: pertama menjelaskan fungsi dokumen elektronik sebagai alat bukti oleh hakim dalam pertimbangan Putusan Perkara Pornografi Nomor: 16/Pid.Sus/2021/PN Kupang dan Nomor: 162/Pid.Sus/2021/PN Kupang. Kedua, untuk mengetahui pertimbangan hakim dalam Putusan Perkara Pornografi Nomor: 16/Pid.Sus/2021/PN Kupang dan Nomor: 162/Pid.Sus/2021/PN Kupang. Penelitian ini dilakukan di Pengadilan Negeri Kupang, menggunakan metode literature review yaitu pengumpulan intisari dari dokumen, buku jurnal, majalah, surat kabar, dan sumber yang berasal dari media elektronik atau laporan-laporan yang berhubungan dengan topik yang diteliti di mana teknik analisis bahan yang penulis gunakan adalah teknik analisis deskriptif. Hasil penelitian yang dilakukan penulis menunjukan bahwa: (1) Alat bukti berupa Informasi elektronik dan/atau dokumen elektronik, bisa berdiri sendiri sebagai alat bukti sebagaimana tercantum dalam Pasal 5 Undang-undang Nomor 19 tahun 2016 tentang ITE dan alat bukti yang tidak berdiri sendiri (pengganti surat dan perluasan bukti petunjuk) Pasal 184 ayat (1) KUHAP. (2) Disparitas dalam perkara pornografi Putusan Nomor: 16/Pid.Sus/2021/PN.Kpg di pidana penjara selama 1 (satu) tahun sedangkan Putusan Nomor: 162/Pid.Sus/2020/PN.Kpg dipidana penjara selama 9 (sembilan) bulan. Perbedaan putusan tersebut merupakan pertimbangan hakim dilatar-belakangi oleh rasa keadilan yang berbeda yang kemudian dapat dibedakan sebagai pertimbangan yuridis dan non yuridis.
Presentación del comentario colectivo del libro de Sevilla, S. y Conill, J. (coords.) Kant después del neokantismo (2020)
Authors: Villanueva Borja 
Published: June 2023

El artículo realiza una presentación de tres comentarios del volumen colectivo editado por Sergio Sevilla y Jesús Conill: Kant después del neokantismo. Lecturas desde el siglo XX (Madrid, Biblioteca Nueva, 2020), así como de la respuesta de Sergio Sevilla a estos.

ORCID
Optimizing lettuce yields and quality by incorporating movable downward lighting with a supplemental adjustable sideward lighting system in a plant factory
Authors: Mutombo Arcel Mulowayi , Yousef Ahmed Fathy , Shen Zhen Hui , Nyimbo Witness Joseph , Zheng Shu He 
Published: June 2023

Background
Lettuce is a vegetable that is increasingly consumed globally, given its nutritional quality. Plant factories with artificial lighting can produce high-yield and high-quality plants. High plant density in these systems speeds up leaf senescence. Wasted energy and lower yield raised labor expenses are some of the bottlenecks associated with this farming system. In order to increase lettuce yields and quality in the plant factory, it is essential to develop cultivating techniques using artificial lighting.

Methods
Romaine lettuce was grown under a developed “movable downward lighting combined with supplemental adjustable sideward lighting system” (C-S) and under a system without supplemental sideward lighting (N-S) in a plant factory. The effects of C-S on lettuce’s photosynthetic characteristics, plant yield, and energy consumption relative to plants grown under a system without N-S were studied.

Results
Romaine lettuce growth and light energy consumption in the plant factory were both influenced favorably by supplementary adjustable sideward lighting. The number of leaves, stem diameter, fresh and dry weights, chlorophyll a and b concentration, and biochemical content (soluble sugar and protein) all increased sharply. The energy consumption was substantially higher in the N-S treatment than the C-S.