bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of a High Sensitive Multiplex Lateral Flow Immunoassay (LFIA) System for Rapid Detection of Methicillin-Resistant Staphylococcus Aureus (MRSA)
Authors: Amini Masoomeh , Pourmand Mohammad Reza , Faridi-Majidi Reza 
Published: February 2023

Background: Methicillin-resistant Staphylococcus aureus (MRSA) has become a worldwide concern as an epidemic bacterium and a cause of nosocomial and community-acquired infections. One of the major problems in the prevention and treatment of infections caused by MRSA strains is their multi-drug resistant trait, which causes the spread of infections and increases the mortality rate. Therefore, a rapid and accurate method is needed to identify MRSA strains, initiate appropriate antibiotic therapy, and control its infection. The aim of this study was to develop a twin lateral flow immunoassay system to detect methicillin-resistant Staphylococcus aureus (MRSA).
Methods: First, BSA blocked AuNPs-anti-peptidoglycan antibody and AuNPs-anti-BSA antibody were used to detect Staphylococcus aureus (S. aureus). Then, AuNPs-anti-PBP2a antibody was used to specifically detect MRSA. Sensitivity, specificity and limit of detection of this twin immunoassay system were assessed using MRSA, methicillin susceptible S. aureus and clinical samples. Results were compared to those of cefoxitin disc diffusion (FOX30) and Polymerase Chain Reaction (PCR) as gold standards.
Results: The Limit of Detection (LOD) of this twin system were 103 and 104 CFU/ml for the first and second strips, respectively. Sensitivity and specificity of this innovative assay in detecting MRSA were 92.30 and 97.36%, compared to FOX30 and PCR, respectively.
Conclusion: High rates of sensitivity and specificity of this initiative system show its high potentials for rapid and accurate detection of MRSA.
Study of DACH1 Expression and its Epigenetic Regulators as Possible Breast Cancer-Related Biomarkers
Authors: Nasirpour Mohammad Hossein , Salimi Mahdieh , Majidi Faezeh , Minuchehr Zarrin , Mozdarani Hossein 
Published: February 2023

Background: Breast carcinogenesis involves both genetic and epigenetic changes. DNA methylation, as well as micro-RNA regulations, are the significant epigenetic phenomena dysregulated in breast cancer. Herein, the expression of DACH1 as a tumor suppressor gene and its promoter methylation status was analyzed in breast cancer tumors. Also, the expression of three micro RNAs (miR-217, miR-6807-3p, and miR-552), which had been previously reported to target DACH1, was assessed.
Methods: The SYBR green-based Real-Time reverse transcription-PCR was used to determine DACH1 and micro-RNAs (miR-217, miR-6807-3p, and miR-552) expression in 120 ductal breast cancer tumors compared with standard control. Also, the promoter methylation pattern of DACH1 was investigated using the Methylation-specific PCR technique.
Results: DACH1 expression was significantly down-regulated in breast tumors (p< 0.05). About 33.5% of tumors showed DACH1 promoter hyper-methylation. The studied micro-RNAs, expression was negatively correlated with DACH1 expression. The highest expressions of miRNAs and higher DACH1 promoter methylation were observed in advanced cancer situations. The Kaplan-Meier survival curves indicated that the overall survival was significantly poor in higher miRNAs and lower DACH1 expression in breast cancer patients (p<0.002).
Conclusion: DACH1 down-regulation may be associated with a poor breast cancer prognosis. The DACH1 down-regulation may be due to epigenetic regulations such as promoter methylation, especially in triple-negative cases. Other factors, such as micro-RNAs (miR-217, miR-6807-3p, and miR-552), may also have an impact. The elevated expression of miR-217, miR-6807-3p, and miR-552, maybe candidates as possible poor prognostic biomarkers in breast cancer management for further consideration.
Immunosuppressive Effects of Two Probiotics, Lactobacillus Paracasei DSM 13434 and Lactobacillus Plantarum DSM 15312, on CD4+ T Cells of Multiple Sclerosis Patients
Authors: Chakamian Khadijeh , Robat-Jazi Behrouz , Moghadasi Abdorreza Naser , Mansouri Fatemeh , Nodehi Masoumeh , Motevaseli Elahe , Izad Maryam , Yekaninejad Saeed , Shirzad Mahdieh , Bidad Kiana , Oraei Mona , Ansaripour Bita , Saboor-Yaraghi Ali Akbar 
Published: February 2023

T cells play an important role in the development and progression of multiple sclerosis (MS), an autoimmune disease of the central nervous system. In the present study, the immunomodulatory impacts of two Lactobacillus strains, L paracasei DSM 13434 and L plantarum DSM 15312, on the frequency and cytokine production of CD4+ T cells in MS patients were explored.
Thirty MS patients were enrolled in this study. The CD4+ T cells were isolated, cultured, and exposed to the media containing cell-free supernatants of L plantarum (group1), L paracasei (group 2), the mixture group of cell-free supernatants of both probiotics (group 3), and vehicle (control) group (group 4). The frequencies of T helper (Th) 1, Th17, Th2, and T regulatory type 1 (Tr1) cells and mean fluorescent intensity (MFI) of the associated cytokines were assessed using flow cytometry. The levels of interleukin 17 (IL-17), transforming growth factor β (TGF-β), and interferon-gamma (IFN-γ) cytokines in supernatants of all groups were measured by enzyme-linked immunosorbent assay.
The percentage of Th1 cells and the MFI of IFN-γ in Th1 cells (CD4+ IFN-γ+) in all three probiotic treatment groups were significantly decreased compared to the control group. However, no significant changes were observed in the proportion and MFI of Th2, Th17, and Tr1 cells. A
significant decrease was observed in IL-17 secretion in the supernatant of cultured CD4+ T cells in all three treatment groups in comparison with control. The levels of TGF-β and IFN-γ were not significantly different among any of the study groups.
Collectively, cell-free supernatants of the lactobacilli showed an in vitro anti-inflammatory effect. However, further studies are needed to prove the real effects of probiotics on MS.
MicroRNA-122 Is More Effective than Rapamycin in Inhibition of Epithelial-mesenchymal Transition and mTOR Signaling Pathway in Triple Negative Breast Cancer
Authors: Ghalavand Majdedin , Dorostkar Ruhollah , Borna Hojat , Mohammadi-Yeganeh Samira , Hashemi Seyed Mahmoud 
Published: February 2023

The fundamental mechanism responsible for the aggressiveness of metastatic cancers such as triple-negative breast cancer (TNBC) is the epithelial-mesenchymal transition (EMT). In cancer microenvironments, the Phosphoinositide 3-kinases (PI3K)-Akt- mammalian target of rapamycin (mTOR) signaling pathway plays a critical role in regulating the EMT mechanism. The current study focuses on the impacts of rapamycin, a newly retargeted chemotherapeutic agent against mTOR, and MicroRNA (miR)-122 on the aggressive behavior of TNBC.
The half-maximal inhibitory concentration (IC50) of rapamycin on 4T1 cells was determined using an MTT assay. Also, miR-122 was transiently transfected into 4T1 cells to study its effect on the pathway. Quantitative real-time polymerase chain reaction (qRT-PCR) was conducted to assess the expression level of central mTOR and EMT-related cascade genes. Moreover, cell mobility and migration were evaluated using scratch and migration assays, respectively.
Both rapamycin and miR-122 significantly decreased the expression levels of PI3K, AKT, and mTOR, as well as ZeB1 and Snail genes. However, no significant change was observed in Twist gene expression. Furthermore, scratch and migration assays revealed that the migration of 4T1 cells was markedly reduced, especially following miR-122 induction. Our experimental findings and gene enrichment studies indicated that miR-122 mainly operates on multiple metabolic pathways, as well as EMT and mTOR, while rapamycin has restricted targets in cancer cells.
Consequently, miR-122 can be considered a potential cancer microRNA therapy option, which can be validated in the future in animal studies to demonstrate its efficacy in cancer control.
Correlation of Expression of MMP-2, ACE2, and TMPRSS2 Genes with Lymphopenia for Mild and Severity of COVID-19
Authors: Ghezelbash Behrooz , Rostami Mehdi , Heidarvand Mohammad , Mafi Alireza , Chegni Hamid , Eskandari Nahid 
Published: February 2023

Some risk causes may be associated with the severity of COVID-19. The central host-pathogen factors might affect infection are human receptor angiotensin-converting enzyme 2 (ACE2), trans-membrane protease serine 2 (TMPRSS2), and SARS-CoV-2 surface spike (S)-protein. The main purpose of this study was to determine the differences in the expression the metalloproteinases-2 (MMP-2), MMP-9, ACE2, and TMPRSS2 genes and their correlation with lymphopenia in the mild and severe types of the COVID-19 patients.
Eighty-eight patients, aged 36 to 60 years old with the mild (n=44) and severe (n=44) types of COVID-19 were enrolled. Total RNA was isolated from the peripheral blood mononuclear cells (PBMCs). The changes of MMP-2, MMP-9, ACE2 and TMPRSS2 gene expression in PBMCs from mild and severe COVID-19 patients were examined by the real time-quantitative polymerase chain reaction (RT-qPCR) assay and, compared between the groups. Data were collected from May 2021 to March 2022.
The mean age of the patients in both groups was 48 (interquartile range, 36–60), and there were no appreciable differences in age or gender distribution between the two groups. The present study showed that a significant increase in the expression of ACE2, TMPRSS2, MMP-2, and MMP-9 genes in the severe type of the COVID-19 patients compared, to the mild type of the COVID-19 patients.
Overall, it suggests the expression levels of these genes on the PBMC surface in the immune system are susceptible to infection by SARS-COV-2 and therefore could potentially predict the patients’ outcome.
Rietveld Refinement Analysis of Lampung Natural Zeolite Catalyst Impregnated Fe with Diffraction Method Using MAUD Software
Authors: Adhani Lisa , Fauzi Ahmad , Navanti Dovina , Lestari Tyastuti Sri 
Published: February 2023

This research characterizes the space group and R-phase crystal structure using the XRD method and Rietveld refinement. Rietveld improvements using the Material Analysis Using Diffraction (MAUD) software are acceptable if the Rwp < 15% and Sig < 2%. MAUD is a diffraction/reflectivity analysis program based primarily on the Rietveld method and here uses X-ray reflectivity data on materials. The intensity of the diffraction data of the powder sample is the appropriate reflection intensity so that the atomic structure of the crystalline material can be determined based on the Le bail characterization technique. The reflectance intensity of this Fe/Zeolite is Rw = 9.51% and Sig = 1.76%. XRD analysis on Lampung activated natural Zeolite before impregnation showed a monoclinic clinoptilolite crystal phase, which gives the lattice parameters on aâ‰ bâ‰ c axis, axis angle Î±=Î³=90oâ‰ Î². The Fe/zeolite in this study is a natural zeolite from Lampung, which was activated and then impregnated with Fe. The Fe/Zeolite catalyst Rietveld Refinement results showed Nepheline's closest crystal phase, which gave the lattice parameters a=bâ‰ c, axis, angle Î±=Î²=90o; Î³=120o, the shape is similar to the hexagonal crystal structure (HCP). These results can be used as an initial reference for the study of the crystallization diffraction pattern in the further development of this catalyst.
Model Kurikulum Sekolah Alam Berbasis Karakter
Authors: Mulyanah Dina , Lestari Ria Yuni , Hardika Legiani Wika 
Published: February 2023

Penelitian ini bertujuan untuk mengetahui penerapan dan peranan model kurikulum Sekolah Alam berbasis karakter Metode yang digunakan adalah deskriptif dengan pendekatan kualitatif. Teknik pengumpulan data yaitu wawancara, observasi dan dokumentasi. Hasil dalam penelitian ini menunjukkan bahwa penerapan model kurikulum Sekolah Alam berbasis karakter dapat membentuk akhlak, leadership, logika dan bisnis siswa di Sekolah Alam Bintaro terintegrasi dalam kegiatan intrakurikuler, ekstrakurikuler dan kokurikuler. Model kurikulum sekolah alam berbasis karakter ini berperan sebagai pedoman dan sarana mentransimisikan -nilai karakter serta mengembangkan potensi setiap siswa. Beberapa hambatan dalam penerapan model kurikulum ini yakni hambatan internal yang datang dari guru dan siswa serta hambatan eksternal yang datang dari orangtua, lingkungan dan teknologi. Dapat disimpulkan bahwa penerapan model kurikulum Sekolah Alam berbasis karakter yang terintegrasi dalam kegiatan intrakurikuler, ektrakurikuler, dan kokurikuler .berperan aktif menjadikan siswanya memlikiki keterampilan leadership, logika dan bisnis serta memiliki akhlak yang baik.
Implementasi Karakter Peduli Lingkungan Sungai Berbasis Kewarganegaraan Ekologis Melalui Program Adiwiyata di Sekolah Dasar
Authors: Fahlevi Reja , Jannah Fathul , Sari Raihanah 
Published: February 2023

Tujuan penelitian ini adalah untuk menganalisis implementasi karakter peduli lingkungan sungai berbasis kewarganegaraan ekologis melalui program Adiwiyata di Sekolah Dasar Negeri 1 Basirih. Penelitian ini menggunakan pendekatan penelitian kualitatif dengan metode studi kasus. Hasil penelitian menunjukan bahwa karakter peduli lingkungan sungai sudah terintegrasi di dalam aspek-aspek program Adiwiyata. Adanya visi, misi dan tujuan sekolah yang memuat tentang lingkungan sungai, kurikulum yang sudah terintegrasi mengenai lingkungan dengan mengintegrasikan semua mata pelajaran materi terkait lingkungan sungai, optimalisasi kegiatan ekstrakulikuler khususnya pramuka terkait dengan lingkungan sungai, ikut berpartisipasi kegiatan-kegiatan yang berhubungan dengan pelestarian dan kebersihan lingkungan sungai, serta tersedianya dengan baik pengelolaan sarana dan prasarana yang ramah lingkungan. Implementasi karakter peduli lingkungan sungai sudah diimplementasikan cukup baik di sekolah tersebut, namun masih sangat perlu dilakukan optimalisasi kembali khususnya mengenai nilai karakter peduli lingkungan sungai. Hal itu harus dilakukan dari tingkat yang paling dasar agar mampu membentuk serta menanamkan kepada peserta didik di sekolah.
Penanaman Nilai-Nilai Karakter Pancasila dalam Pembelajaran Pendidikan Kewarganegaraan berbasis Polysynchronous di Era New Normal
Authors: Zuriah Nurul 
Published: February 2023

Penelitian ini bertujuan untuk menganalisis problematika penanaman nilai-nilai karakter Pancasila dalam Pembelajaran Pendidikan Pancasila dan Kewarganegaraan (PPKn) Berbasis Polysynchronous di Era New Normal yang dilakukan di Universitas Muhammadiyah Malang (UMM). Metode penelitian menggunakan deskriptif kualitatif dengan analisis interaktif model Milles & Huberman. Informan terdiri dari para dosen dan mahasiswa yang menempuh mata kuliah Pendidikan Pancasila dan Pendidikan Kewarganegaraan pada semester gasal 2020/2021. Teknik pengambilan sampel menggunakan purposive sampling dan snowball sampling. Hasil penelitian menunjukkan bahwa terdapat permasalahan dalam penanaman nilai-nilai Pancasila dalam Pembelajaran PPKn dengan platform Polysynchronous di Era New Normal. Ada tiga komponen penting dalam penelitian ini, yaitu: (1) masalah substansi nilai yang dikembangkan; (2) metode penanaman nilai yang dikembangkan; (3) penggunaan evaluasi penanaman nilai. Ada beberapa faktor pendukung dan penghambat dalam implementasinya. Hal ini mengindikasikan bahwa penanaman nilai-nilai Pancasila dalam Pembelajaran PPKn yang menggunakan platform polysynchronous membutuhkan pencermatan, elaborasi dan pengembangan lebih lanjut untuk efektivitasnya di masa mendatang.
Reading the Struggle of Moral Values in the Glamour Life of Batu City Tourism Society
Authors: Kewuel Hipolitus Kristoforus , Prawoto Sigit 
Published: February 2023

Kota Wisata Batu telah terkenal di tingkat nasional dan internasional. Berbagai tempat wisata ada di sana dengan berbagai fasilitas pendukung seperti hotel, kehidupan malam, dan lainnya. Situasi ini, dapat dipahami sebagai konsekuensi dari predikat Batu sebagai kota wisata. Namun, masyarakat Kota Batu juga merupakan masyarakat yang religius yang kuat dengan nilai-nilai kehidupan beragama dan norma-norma tata kelola sosial. Masyarakat harus mengalami gejolak yang datang mewarnai kehidupan sosial keagamaan mereka. Penelitian ini mengungkapkan sejauh mana hal-hal ini telah diproses oleh masyarakat dan lembaga-lembaga penanggungjawab terkait. Dengan menggunakan metode etnografis kualitatif, hasil penelitian menunjukkan bahwa lembaga seperti Perhimpunan Hotel dan Restoran Indonesia (PHRI), Dinas Pariwisata, Forum Kerukunan Umat Beragama (FKUB), Majelis Ulama Indonesia (MUI), dan lembaga keagamaan lainnya telah menerapkan prinsip moral dalam proses pariwisata di Kota Batu. Namun, dampak kehidupan glamour di dunia modern rupanya telah menjadi pengalaman pariwisata yang tidak terelakkan di luar kendali dan kerja keras mereka dan itu akan terus menjadi bagian perjuangan mereka dalam menghidupi pariwisata di Kota Batu.
Analisis Keberadaan Hidden Curriculum dalam Pengembangan Delapan Belas Karakter Bangsa pada Siswa Sekolah Dasar
Authors: Salamor Lisye , Ritiauw Samuel Patra 
Published: February 2023

Tujuan penelitian ini adalah untuk mengetahui bagaimana keberadaan hidden curriculum dalam pengembangan delapan belas karakter bangsa pada peserta didik di sekolah dasar di Kota Ambon, dengan menggunakan metode kualitatif dengan pendekatan kuantitatif. Hasil penelitian pada SD Kristen 2 Waimahu sebagaimana temuan baik kepala sekolah, guru dan peserta didik sebagai subjek, menggambarkan keberadaan hidden curriculum dalam pengembangan karakter bangsa berpusat pada kemitraan antara sekolah dan keluarga. Dalam keberadaannya di sekolah telah terintegrasi dalam perencanaan program semester, implementasi pembelajaran dan evaluasi pembelajaran. Ada faktor penghambat yaitu kurangnya intensitas komunikasi orang tua sebagai bagian dari pendukung karakter peserta didik. Dua dari delapan belas karakter yang harus dikembangkan oleh kedua sekolah yaitu karakter mandiri dan karakter peduli lingkungan. Terdapat pendapat berbeda oleh orang tua, dimana hasil temuan menunjukkan bahwa buku komunikasi peserta didik hanya formalitas. Kondisi ini menunjukan ketidakseriusan sekolah dalam mengupayakan pengembangan karakter peserta didik, dengan demikian sekolah dan keluarga harus membangun kemitraan secara terpadu dan berkesinambungan.
Aktualisasi Karakter Disiplin Dalam Pengembangan Self- Regulated Learning Melalui Intervensi Model Classroom Community Patnership
Authors: Salamor Lisye 
Published: February 2023

Tujuan penelitian ini adalah untuk mengetahui ; (1) bagaimana pembentukan karakter disiplin peserta didik selama ini pada Sekolah Dasar di Kota Ambon, (2) bagaiman karakteristik model Classroom community Patnership (CCP), (3) bagaimana intervensi model CCP dalam pengembangan self-regulated learning dengan aspek karakter disiplin pesera didik didalamnya. Metode research and development digunakan pada penelitian ini, dengan prosedur; tahapan studi pendahuluan, tahapan pengembangan yang terdiri dari pengujian pada skala terbatas dan lebih luas, dan tahapan validasi model akhir. Teknik proposive sample digunakan dengan memperhatikan karakteristik dan klaster sekolah. Studi pendahuluan dilakukan pada empat sekolah. Studi Pengembangan dilakukan pada enam sekolah, dan validasi model akhir dilakukan pada dua sekolah dengan kelas yang berbeda (kelas kontrol dan kelas eksperimen). Teknik pengumpulan data yang digunakan melalui wawancara, observasi, dan angket. Untuk melihat peningkatan karakter disiplin teknik analisis data dilakukan dengan N-Gain. Hasil pengembangan ditemukan terdapat peningkatan yang signifikan karakter disiplin melalui intervensi model CCP. Kolaborasi antar Tripusat pendidikan menjadi aspek penting dalam peningkatan karakter disiplin.
Korelasi Pelepasan Moral dan Cyberbullying pada Remaja di Madrasah Aliyah Negeri di Sleman
Authors: Ru'iya Sutipyo , Sutrisno  , Suyadi  , Kistoro Hanif Cahyo Adi 
Published: February 2023

Penelitian ini bertujuan untuk mengetahui tingkat cyberbullying dan pelepasan moral pada remaja siswa Madrasah Aliyah Negeri se Sleman Yogyakarta dan hubungan pelepasan moral dengan cyberbullying. Jenis penelitian ini adalah kuantitatif korelasional, dengan subyek penelitian berupa sampel sebanyak 152 orang siswa. Alat pengumpulan data berupa skala cyberbullying dan pelepsan moral, yang dikumpulkan melalui google form. Data dianalisis dengan analisis deskriptif dan analisis korelasi Spearman's rho. Hasil analisis deskriptif menunjukkan sebagian besar siswa Madrasah Aliyah Negeri telah melakukan pelepasan moral dan cyberbullying. Hasil analisis korelasi antara pelepsan moral dan cyberbullying diperoleh nilai 0,322 dengan nilai signifikansi 0,000 yang berarti terdapat hubungan yang rendah dan signifikan anara kedua variabel yang diteliti. Namun demikian, pelepsan moral dan cyberbullying harus menjadi perhatian penting bagi insan pendidik khususnya, karena cyberbullying dapat menjadi penyebab perilaku-periaku negatif yang lain dan lebih besar. Oleh karena itu, perlu adanya penangan khusus pencegahan cyberbullying agar perilaku ini menjadi berkurang bahkan tidak terjadi pada siswa Madrasah Aliyah Negeri.
Tingkat Kompetensi Kewarganegaraan Ekologis Guru Pendidikan Pancasila dan Kewarganegaraan di Sekolah Menengah Pertama
Authors: Sarbaini  , Fahlevi Reja 
Published: February 2023

Penelitian ini dilatarbelakangi oleh kondisi ekosistem sungai di Banjarmasin. Peran guru Pendidikan Pancasila dan Kewarganegaraan dalam perspektif Kewarganegaraan Lingkungan perlu dioptimalkan. Namun belum diketahui dan belum ada penelitian terhadap tingkat dan dimensi kewarganegaraan lingkungan di tingkat Sekolah Menengah Pertama, khususnya terhadap guru Pendidikan Pancasila dan Kewarganegaraan. Pendekatan penelitian ini adalah penelitian kuantitatif. Teknik pengumpulan data dan informasi dilakukan melalui kuesioner, wawancara dan studi dokumentasi. Teknik analisis data menggunakan kriteria dan kategori Tingkat Kewarganegaraan Lingkungan berdasarkan kategori dari Karetekin. Temuan penelitian menunjukkan tingkat kewarganegaraan lingkungan guru Pendidikan Pancasila dan Kewarganegaraan secara keseluruhan berada pada level sedang, terutama dalam indikator sikap warga negara lingkungan yakni menggunakan lebih banyak sumber daya alam daripada yang kita butuhkan, tidak mengancam kesehatan dan kesejahteraan orang di masa depan berada dalam tingkat yang sangat rendah. Tingkat Kewarganegaraan lingkungan guru Pendidikan Pancasila dan Kewarganegaraan belum mencapai tingkat yang memuaskan, karena masih masih berada pada tingkat sedang dan rendah. Rekomendasi dalam penelitian ini perlu penguatan dan penegakkan nilai-nilai ekologis melalui sistem pendidikan yang secara konsisten memperkuat nilai-nilai ekologis. dan memungkinkan perilaku pro-lingkungan dan pada gilirannya memberikan penguatan untuk nilai-nilai ekologis.
Study on the removal of Pb(II) from water by coated sulfur-modified nanoscale zero-valent iron
Authors: Tang Kan , Zhang Shuqin , Ren Dajun , Zhang Xiaoqing , Zhang Zhuang , Zhang Xu 
Published: February 2023

ABSTRACT

Being prepared by a liquid-phase reduction method, sulfur-modified nanoscale zero-valent iron (S-nZVI) was then coated with sodium alginate (SA) to form gel beads (SAS-nZVI) which are capable of removing Pb(II) from water. SAS-nZVI was characterized by SEM, EDS, FTIR, XRD, and BET, and its removal effect on Pb(II) in water, including the effects of pH, adsorbent dosage, shaking time, and initial concentration of lead, was also studied. The results demonstrated that the maximum removal efficiency of Pb(II) by SAS-nZVI was 97.89%, and the maximum uptake was 246.40 mg/g. In the Pb(II) removal behavior study, the pseudo-second-order kinetic model and the Langmuir isotherm model were found to fit the adsorption process well. SAS-nZVI was easier to recycle from the reaction system, and the removal efficiency of SAS-nZVI to Pb(II) in water was still able to reach 82.75% after five cycles. Therefore, this study suggests that SAS-nZVI has a high removal capacity for Pb(II) and great potential in water pollution treatment.