bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mapping global greenhouse gases emissions: an interactive, open access web application
Authors: Andrieu Baptiste , Le-Boulzec Hugo , Delannoy Louis , Verzier François , Winter Guillaume , Vidal Olivier 
Published: March 2023

Abstract

Consumption-based carbon assessments are essential for evaluating climate change responsibility. However, the results vary greatly depending on the scope chosen, making them confusing to non-expert readers and hindering their use for policymaking. This study aims to shed light on all the possible ways to calculate carbon footprints and on the implications of choosing one method over another. Integrating emissions associated with capital goods in the global multi-regional input-output database EXIOBASE, we calculate carbon footprints for 49 world regions between 1995 and 2019 and build an interactive, open access, visual web application representing all possible scopes as Sankey diagrams. We show that the ranking of carbon footprints across regions, and thus the national responsibility for ecological breakdown, change significantly depending on the scope chosen. Our results further underline the need to include capital emissions in input-output models to better assess the large inequality in international carbon footprints.
Depression and Glycemic Control among Adult Type 2 Diabetic Patients: A Crossectional Study in a Comprehensive Specialized Hospital, Jigjiga, Ethiopia
Authors: Yimam Seid , Muhye Ahmed , Hassen Kalkidan , Tadesse Samuel , Banjaw Zelalem , Ibrahim Mohammed 
Published: March 2023

Abstract
Background
Globally, there is an alarming rise in type 2 diabetes mellitus prevalence, with the highest rate of increment observed in developing countries, including Ethiopia. The disease has a multifaceted impact, ranging from physical and mental symptoms to socioeconomic consequences. While most of these burdens have due consideration, the mental health impact of diseases such as depression is often unnoticed, undiagnosed, or untreated. More importantly, depression is known to have a higher likelihood of occurrence in patients with type 2 diabetes mellitus. Hence, the present study aimed to assess the prevalence of depression and its sociodemographic predictors, clinical predictors, and glycemic control among adult type 2 diabetic patients at Sheik Hassan Yabare Comprehensive Specialized Hospital, Jigjiga, Ethiopia.
Methods
A hospital-based cross-sectional study was conducted using a systematic random sampling method from October 3 to November 13, 2022. The Patient Health Questionnaire was used to assess depression, while glycemic control was measured using glycated hemoglobin (HgA1c). The data was entered into Epidata version 4.6 for data entry and then exported to SPSS version 26 for analysis. Multiple logistic regressions with the backward elimination method were performed, and a p-value of < 0.05 with a 95% confidence interval was taken as statistically significant.
Results
A total of 263 participants were included, with a response rate of 94.6%. Of the respondents, 134 (51%) were male, making up more than half of the total. The overall prevalence of depression was 47.1% (95% CI: 41.1–53.2). Depression was further classified, as follows, based on its severity: the majority of 66 (25.1%) had mild depression, followed by 44 (16.7%) with moderate depression, 9 (3.4%) with moderately severe depression, and 5 (1.9%) with severe depression. A multivariable logistic regression analysis indicated that poor glycemic control (AOR = 1.93; 95% CI = 1.05, 3.53), DM complications (AOR = 2.02; 95% CI = 1.09, 3.74), and DM duration of 5–10 years since diagnosis (AOR = 2.29; 95% CI = 1.21, 4.34) were independently associated with depression.
Conclusions
Our study revealed a significant burden of depression among type 2 diabetes mellitus patients receiving follow-up care at the hospital. Glycemic control, the presence of complications, and longer duration of diabetes were identified as predictors of depression. Therefore, concerned stakeholders should work to improve blood sugar control and promote healthy behavior, particularly among those with complications or who have been sick for an extended period of time.
Labeling in a Latinx Community: Public Health Implications for Youth and Role in Community Narratives
Authors: Caballero Elodia , Minnis Alexandra , Parmar Deepika , Zerofsky Melissa , Comfort Megan , Raymond-Flesch Marissa 
Published: March 2023

Abstract
Background: Youth of color are disproportionately subjected to negative formal and informal labels by parents, peers, and teachers. This study examined the consequences of such labels on health-protective behaviors, wellbeing, peer networks and school engagement.
Methods: In-depth interviews were conducted with 39 adolescents and 20 mothers from a predominantly Latinx and immigrant agricultural community in California. Teams of coders completed iterative rounds of thematic coding to identify and refine key themes.
Results:Dichotomous labeling of “good” and “bad” was pervasive. Youth labeled as “bad” experienced limited educational opportunities, exclusion from peers, and community disengagement. Additionally, preservation of “good kid” labels compromised health protective-behaviors including foregoing contraception. Participants pushed back on negative labeling when it was applied to close family or community acquaintances.
Discussion: Targeted interventions that foster social belonging and connection rather than exclusion may facilitate health protective behaviors and have positive implications for future trajectories among youth.
Prevalence and Characteristics of Vitamin B12 Deficiency Among Patients with Type-2 Diabetes Mellitus in Bahrain- A Cross-Sectional Study
Authors: Alawainati Mahmood , Ayoob Zahra Ahmed , Sarhan Shatha , Ayoob Zainab 
Published: March 2023

Abstract
Background: Type-2 Diabetes Mellitus is a chronic metabolic disease characterized by inappropriate hyperglycemia and defects in insulin function. Vitamin B12 is an essential water-soluble vitamin that has a fundamental role in the synthesis of fatty acids, DNA and myelin. Metformin, an oral hypoglycemic agent, was linked to low levels of vitamin B12. This study aimed to determine the prevalence and determinants of vitamin B-12 deficiency among patients with type-2 Diabetes mellitus attending primary healthcare centers in Bahrain.
Methods: A cross-sectional study was conducted at five primary healthcare centers in Bahrain. Serum B-12 levels were measured for all patients. Vitamin B-12 levels ≤ 221 pmol/L were considered low, while vitamin B-12 levels of more than 221 pmol/L were considered normal.
Results:A total of 691 patients were included in our study with an average age of 58.5±11.2 years. Most participants had hypertension (n=436, 63.1%) and hyperlipidemia (n=367, 53.1%). As high as 92% of the participants were on Metformin and 42.1% (n= 291) were using Insulin formulations. The mean vitamin B-12 level among participants was 278.0 ± 179.3 pmol/L. We found that 40.1% of the patients (n=277) had vitamin B-12 deficiency. Being treated with metformin was the only significant determinant of low vitamin B-12 levels among the cohort (P=0.022).
Conclusion: Vitamin B-12 deficiency is prevalent among patients with type-2 diabetes, especially among those on Metformin. Screening for vitamin VB12 deficiency should be considered in diabetic patients especially if treated with Metformin.
Assessment of asphalt pavement aging condition based on GF-2 high-resolution remote sensing image
Authors: Wang Han , Yang Dayong , Xie Zhiwei , Wang Jingwen , Hao Zhigang , Zhou Fanyu , Wang Xiaona 
Published: March 2023

Abstract
The aging condition of asphalt pavement is a crucial basis for traffic infrastructure evaluation. Due to the long time and high cost required to monitor and identify the aging condition of asphalt pavement, many current studies have focused on the application of satellite remote sensing methods. Based on the previous research results, we used PCI data and GF-2 high-resolution remote sensing images. The experimental results show that the DHI, RHI, and NDHI using GF-2 data can reflect the aging of asphalt pavement to varying degrees. This paper presents an entirely new asphalt pavement aging index, named the New Aging Index (NAI). It can not only perfectly identify the different aging conditions of asphalt pavements, but also has a significant distinguishing effect on the pavement interference information such as shadows and vehicles. NAI combined with GF-2 high-resolution remote sensing images can be used to assess the aging condition of asphalt pavement.
The Sensitive Regions of Surface Air Temperature and Terrestrial Precipitation to Global Warming, IPO and AMO
Authors: Xu Chengyu , Tao Li 
Published: March 2023

Abstract
Against the background of global warming (GW), the distribution of decadal (10–20-year), multidecadal (20–50-year) and secular (>50-year) variabilities and their causes of surface air temperature (SAT) and terrestrial precipitation were explored. We applied the singular spectrum analysis method to categorize the low-frequency variabilities of global SAT and terrestrial precipitation anomalies. Three sea surface temperature (SST) modes were identified through singular value decomposition that affect the low-frequency variabilities of global SAT and terrestrial precipitation anomalies—namely, the GW, Interdecadal Pacific Oscillation (IPO) and Atlantic Multidecadal Oscillation (AMO) modes. The sensitive regions of SAT and terrestrial precipitation to GW, IPO and AMO were validated through an information flow method. Significant decadal and multidecadal variabilities of SAT were found to exist over the Pacific and Northern Atlantic, respectively, because of the IPO and AMO. In terms of terrestrial precipitation, a large area with a wet trend was found over Eurasia at mid-to-high latitudes, and this trend was especially remarkable in the boreal winter half-year (November–April), as compared with that in the boreal summer half-year (May–October). As a result, it could be concluded that GW is the trigger of the wet trend. By employing artificial neutral networks with a self-organized map to cluster the key patterns of vertically integrated water vapor flux, we found that the synopitic circulation related to the wet trend is characterized by westerly flow that transports water vapor from the northeastern Atlantic to Eurasia, which is favorable for precipitation there both in the boreal winter and summer half-year.
Node MCU based Pocket Cloud Memory System for Secure Data Storage
Authors: Manjula S. , Sudha M. Swarna , Kumar D. Mohan 
Published: March 2023

Abstract
Many people nowadays rely on storage devices such as external hard drives and pen drives to store files. The users reported that their drives kept disconnecting and causing problems in some operating systems. Some models have their own set of problems. If the user has important data that has been compromised by infected files, viruses, or malware, the user will undoubtedly require adequate protection. These drives require protection against file loss, malware, and hardware failure. In this work, an innovative wireless handheld storage device called Pocket Cloud has been proposed, which includes data query processing, and IoT sensor data processing. When connected to a power supply, it can be used as a wired storage device. Users can also transfer files between cloud services. Volumes can also be attached, detached, swapped, and edited. The pocket cloud provides remote file access, additional cloud storage, and convenient web backup options. For added security, the user can encrypt data with a key before uploading it to the device.
Delay tumor progression with the introduction of engineered impactive cells
Authors: Hong Dengli , Li Shuiping , Ma Junxia , Mu Lili , Wu Wanying , Hu Ye , Wang Yiding , Guo Xiaolin , Cai Jiejing , Wang Xi , Wei Jieping , Liu Yanjun , Xie Hongyu 
Published: March 2023

Abstract
The complete eradication of tumor cells is extremely challenging. An alternative strategy is tumor containment, which utilizes the interaction of tumor cells and has achieved promising results. However, effective interaction and controllability are not guaranteed for a given tumor. Here, we proposed a novel strategy comprising an impactive cell population and a control system and realized it in leukemic mouse model. To identify impactive cells, we xenografted six leukemic cell lines together. We found NALM-6 cells strongly impact the infiltration of other leukemic cells. To control NALM-6 cells, we introduced the herpes simplex virus thymidine kinase/ganciclovir suicide system. We found they effectively controlled the infiltration of NALM-6 cells. To evaluate the effectiveness, we used this strategy in mice xenografted with REH cells. The survival time was significantly elongated. In summary, our strategy guaranteed the impact and controllability of effector cells, thereby extending the tumor containment strategy.
Analysis of fecal microbiome and metabolome changes in goats with pregnant toxemia
Authors: Jin Bingyan , Wang Ruoqian , Hu Jiada , Wang Yan , Cheng Panpan , Zhang Jiancong , Zhang Jiahui , Xue Gang , Zhu Yan , Zhang Yunhai , Fang Fugui , Liu Ya , Li Yunsheng 
Published: March 2023

Abstract
Background Pregnancy toxemia is a common disease, which occurs in older ewes that are pregnant with multiple lambs in the third trimester. Most of the sick goats die within a few days, which can seriously impact the economic benefits of goat breeding enterprises. The disease is believed to be caused by malnutrition, stress, and other factors, that lead to the disorder of lipid metabolism, resulting in increased ketone content, ketosis, ketonuria, and neurological symptoms. However, the changes in gut microbes and their metabolism in this disease are still unclear. The objective of this experiment was to evaluate the effect of toxemia of pregnancy on the fecal microbiome and metabolomics of ewes.
ResultsEight pregnant ewes suspected of having toxemia of pregnancy (PT group) and eight healthy ewes during the same pregnancy (NC group) were selected. Clinical symptoms and pathological changes at necropsy were observed, and liver tissue samples were collected for pathological sections. Jugular venous blood was collected before morning feeding to detect biochemical indexes, and fecal samples were collected simultaneously using 16SrRNA and Liquid Chromatography-Mass Spectrometry (LC-MS) techniques to detect different flora and metabolites. Autopsy revealed that the liver of the pregnancy toxemia goat was enlarged and earthy yellow, and the biochemical results showed that the serum levels of aspartate aminotransferase (AST) and β-hydroxybutyric acid (B-HB) in the PT group were significantly increased, while calcium (Ca) levels were significantly reduced. Sections showed extensive vacuoles in liver tissue sections. The microbiome analysis found that the richness and diversity of the PT microbiota were significantly reduced.Metabolomic analysis showed that 125 differential metabolites were screened in positive ion mode and enriched in 12 metabolic pathways. In negative ion mode, 100 differential metabolites were screened and enriched in 7 metabolic pathways.
ConclusionsEvidence has shown that the occurrence of pregnancy toxemia is related to gut microbiota, and further studies are needed to investigate its pathogenesis and provide research basis for future preventive measures of this disease.
Mitochondrial regulation of GPX4 inhibition-mediated ferroptosis in acute myeloid leukemia
Authors: Akiyama Hiroki , Zhao Ran , Ostermann Lauren , Li Ziyi , Baran Natalia , Yazdani Samar , Ayoub Edward , Pryor Malcolm , Nishida Yuki , Mak Po , Ruvolo Vivian , Carter Bing , Andreeff Michael , Ishizawa Jo 
Published: March 2023

Abstract
Resistance to apoptosis in acute myeloid leukemia (AML) cells causes refractory or relapsed disease, associated with dismal clinical outcomes. Ferroptosis, a mode of non-apoptotic cell death triggered by iron-dependent lipid peroxidation, has been investigated as potential therapeutic modality against therapy-resistant cancers, but our knowledge of its role in AML is limited. We investigated ferroptosis in AML cells and identified its mitochondrial regulation as a therapeutic vulnerability. GPX4 inhibition induces ferroptosis in AML cells, accompanied with characteristic mitochondrial lipid peroxidation, exerting anti-AML effects in vitro and in vivo. Electron transport chains (ETC) are primary sources of coenzyme Q10 (CoQ) recycling for its function of anti–lipid peroxidation in mitochondria. We found that the mitochondria-specific CoQ potently inhibited GPX4 inhibition–mediated ferroptosis, suggesting that mitochondrial lipid redox regulates ferroptosis in AML cells. Consistently, Rho0 cells, which lack functional ETC, were more sensitive to GPX4 inhibition–mediated mitochondrial lipid peroxidation and ferroptosis than control cells. Furthermore, degradation of ETC through hyperactivation of a mitochondrial protease, caseinolytic protease P (ClpP), synergistically enhanced the anti-AML effects of GPX4 inhibition. Collectively, our findings indicate that in AML cells, GPX4 inhibition induces ferroptosis, which is regulated by mitochondrial lipid redox and ETC.
Are TIPs involved in the stomatal regulation in sunflower under different conditions?
Authors: Abdelhakam Selwan , Rabei Sami H. , Nada Reham M. , Abogadallah Gaber M. 
Published: March 2023

Abstract
In this study we aimed at elaborating the contribution of sunflower stomata on both sides in the stomatal conductance (gs) and the relation between its regulation and specific aquaporins expression under different conditions. Our results indicated higher stomatal index of the adaxial than the abaxial as well as the photosynthesis (A), manifesting that stomatal index was a key factor for A and/or stomatal conductance (gs). Sunflower plants could absorb CO2 from both leaf surfaces and therefore have a more efficient photosynthetic CO2 uptake and fixation rates than other C3 species maintaining the high concentration of intercellular CO2. We also indicated that stomatal regulation rather than stomata per se determines the rate of transpiration (E). Key regulators of stomata are plant vacuoles in which aquaporins (TIPS) function. Insilico characterization of sunflower TIPS deduced from database indicated a conserved motif MIP with other species proved to transport water and involved in many different physiological processes. Inconsistent regulation of TIPs under different conditions was detected indicating TIPs were not involved in stomatal regulation at these conditions. Hierarchical analysis showed that TIP7 was distantly related to the other sunflower identified aquaporins.
WITHDRAWN: Enhancing Cloud Storage Security with Multi-Authority Privacy Preserving Data Signcryption using Rijndael Encryption and HMAC
Authors: A Abirami , S Bhuvaneswari , K Chandraprakash Reddy , M Eshwanth G , S Imran Khan 
Published: March 2023

Abstract
In recent times, data storage security in cloud storage systems has become a major concern due to the rising incidents of security breaches and data theft by attackers or hackers. To address this challenge, researchers have focused on developing efficient fine-grained access mechanisms in cloud storage space. Attribute Based Encryption (ABE) and Attribute Based Signature (ABS) have emerged as promising techniques for providing confidentiality and authenticity, respectively, to different types of data. These techniques are combined to form Attribute Based Signcryption (ABSC). However, most existing solutions are impractical for real-world scenarios due to the involvement of multiple third-party services and high computation and communication overhead. Therefore, we propose a novel ABSC technique that provides privacy protection and public verifiability for the signcryptor and ciphertext, respectively. Our approach aims to enhance the security of cloud storage systems by addressing the limitations of existing solutions.
Investigating rainfall-runoff and turbidly behavior during the rainy season in west of Japan
Authors: Sawaf Mohamad Basel Al , Kawanisi Kiyosi , Bahreinimotlagh Masoud 
Published: March 2023

Abstract
Understanding the recent variability in massive rainfall patterns is essential to provide a clear image about underlying hydrological processes that occur over a watershed scale. The main objective of this study is to investigate the variability of rainfall events in Western Japan as a result of climate change and examine the related runoff-turbidity dynamics during rainy season. To fulfill the research objectives, we investigated the changeability of the precipitation records in the Gōno River watershed for the last two decades and the related runoff-turbidity behavior during floods using the turbidity-discharge (T-Q) loops and quantified using an improved hysteresis index. The findings revealed a kind of intense rainfall periodicity of 3 ~ 4 years. In addition, spatial pentads analysis exhibited various intensities of accumulated precipitation suggesting that there is no specific spatial zone of extreme rainfall. Regarding the turbidity-discharge behavior, it was found that clockwise hysteresis patterns were induced by sediment sources from near channel areas, alternatively, anticlockwise pattens were produced due to soil erodibility from the nearby areas. Another interesting finding was a notable behavior of turbidity during floods such as “bursts” or “local peaks” may represent an earlier (or later) arrival of turbid waters from nearby distant sources at an upstream section as a result of an intense precipitation. One of the fundamental challenges in the quantification of hysteresis patterns is that there is no accepted definition on how to determine the start and the end of a flood event which may led to a bias in the quantification of these patterns.
Assessing the Readiness of Staff at Uitm Pahang Toward Big Data Adoption
Authors: Ujang Suriyati , Saad Zuria Akmal , Mohamad Mastura , Abdullah Mohd Amli , Sarimin Siti Norbaini 
Published: March 2023

Abstract

The adoption of Big Data (BD) in higher education is still in its initial stages compared to other sectors. This has led to numerous frameworks for BD adoption in higher education, as different studies cover different scopes and objectives. This study aims to explore the readiness of University Teknologi MARA Cawangan Pahang (UiTM Pahang) towards BD adoption. Diffusion of Innovation and Technology, Environment, and Organization Theories will be used to explore the organization's readiness, while Unified Theory and Use of Technology elements will explore individual acceptance of BD. According to the findings, 25.7% of respondents are aware of the term "big data" but lack the skills to apply it in their workplace, and the majority (80%) of UiTM Pahang staff agree that adopting big data will increase their productivity. In the context of the use of technology, 70% of the respondents agreed that UiTM Pahang would support the use of big data in the organization. Approximately 80% of respondents believe that using big data will assist UiTM Pahang improve student performance, the teaching process, decision-making, and knowledge of future trends, thereby assisting in changing the academic curriculum. Hence, to increase the awareness and readiness of the staff toward BD adoption at UiTM Pahang, the top management can impart BD training and motivational support. The positive outlook of the overall state would lead to the ongoing improvement of the education system with continuous aid from both management and staff.