bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dynamics of multidimensional poverty and its determinants among the middle-aged and older adults in China
Authors: Wang Qun , Shu Lu , Lu Xiaojun 
Published: March 2023

AbstractThe aim of this study was to understand the dynamics of multidimensional poverty and its determinants among mid-aged and older adults. We used 2011, 2013, 2015, and 2018 data from the China Health and Retirement Longitudinal Study. We utilised basic descriptive statistics, the poverty transition matrix, Kaplan–Meier estimates, and the discrete-time proportional hazards model for data analysis. From 2011 to 2018, the incidence of multidimensional poverty among mid-aged and older people basically decreased, but the average poverty intensity remained stable. Most mid-aged and older adults had transient multidimensional poverty. The longer an individual remained multidimensionally poor, the smaller the probability of exit from poverty; The longer an individual remained nonpoor after escaping from poverty, the smaller the probability of returning to poverty. As to other factors, individual characteristics, family structure, living arrangements, social capital, and living areas significantly affected the risks of multidimensional poverty exit and reentry. Based on these results, the government should implement targeted interventions for frail older adults with the identified characteristics to prevent them from persistent multidimensional poverty or return to poverty.
Application of GIS and AHP for land use suitability analysis: case of Demirci district (Turkey)
Authors: Topuz Mustafa , Deniz Mehmet 
Published: March 2023

AbstractThe current study aims to create a land use suitability map for the Demirci district of Manisa province in which the Analytical Hierarchy Process, one of the multi-criteria decision-making techniques, and Weighted Overlay methods are used. Eleven factors (soil, LCC, OSC, erosion, soil depth, elevation, slope, aspect, geomorphology, temperature, and precipitation) affecting land use were determined according to previous similar studies and expert consultation. Priorities of basic land use types were also designated based on expert consultation. After this process, layer maps were created using GIS software. With these layer maps, a land use suitability map of the district was drawn through an analytic hierarchy process and weighted overlay analysis. The suitability of the land in terms of three different forms of use, namely forest, meadow-pasture, and agricultural areas was revealed. As a result of the study, it has been revealed that the most incompatibility between the current land use and land use suitability is in agricultural land. The results also indicate that most of the areas which should be pasture are used as agriculture and forest areas. The southern slopes of the Simav-Demirci Mountains, Asi Tepe, and its surroundings are suitable for forest areas. The study not only contributes to the local and national economy by revealing unsuitable land uses in the research area suggesting different ways of use but also helps the continuity of the ecosystem by ensuring the protection of natural areas.
Global Accelerometer-derived Physical Activity Levels from Preschoolers to Adolescents: A Multilevel Meta-analysis and Meta-regression
Authors: Chen Han , Liu Jiling , Bai Yang 
Published: March 2023

Abstract

Background
Global level physical activity surveillance studies were primarily based on self-report data that could generate inaccurate results.

Purpose
To investigate global accelerometer-measured daily moderate to vigorous physical activity (MVPA) changes from preschool age to adolescence as well as gender differences in MVPA while adjusting for the geographic regions and major MVPA cut points.

Methods
A comprehensive search was conducted through August 2020 that includes 30 databases such as Academic Search Ultimate, Child Development & Adolescent Studies, Education Full Text, ERIC, General Science, PsycINFO, ScienceDirect, and SPORTDiscuss. We included both cross-sectional and longitudinal MVPA tracking studies with daily MVPA being measured by waist-worn accelerometers and determined by either Freedson 3 METs, 4 METs, or Evenson cut points for preschoolers, children, and adolescents.

Results
Researchers analyzed 84 studies reporting on 124 effect sizes with a total of 57,587 participants. The combined data showed significant MVPA differences among various continents of participants (p &lt; .001) or cut points (p &lt; .05–.001) for both preschoolers, children, and adolescents. Globally, when continents and cut points were controlled, individuals’ daily MVPA time decreased every year by an average of 7.88, 10.37, and 6.68 min from preschool age to adolescence, preschool age to children, and children to adolescence, respectively. When cut points and continents were controlled, boys had significantly higher daily MVPA than girls for all three age groups (p &lt; .001).

Conclusions
Globally, individuals’ daily MVPA starts to decline dramatically as early as the beginning of preschool age. Early intervention is needed to counteract the high decline rate in MVPA.
Cost-effectiveness of physical activity programs and services for older adults: a scoping review
Authors: Pinheiro Marina B , Howard Kirsten , Oliveira Juliana S , Kwok Wing S , Tiedemann Anne , Wang Belinda , Taylor Jennifer , Bauman Adrian , Sherrington Catherine 
Published: March 2023

AbstractBackgroundEvidence supporting physical activity for older adults is strongly positive. Implementation and scale-up of these interventions need to consider the value for money. This scoping review aimed to assess the volume of (i) systematic review evidence regarding economic evaluations of physical activity interventions, and (ii) of cost utility analysis (CUA) studies (trial- or model-based) of physical activity interventions for older people.MethodsWe searched five databases (January 2010 to February 2022) for systematic reviews of economic evaluations, and two databases (1976 to February 2022) for CUA studies of physical activity interventions for any population of people aged 60+ years.ResultsWe found 12 potential reviews, two of which were eligible for inclusion. The remaining 10 reviews included eligible individual studies that were included in this review. All individual studies from the 12 reviews (n = 37) investigated the cost-effectiveness of structured exercise and most showed the intervention was more costly but more effective than no intervention. We identified 27 CUA studies: two investigated a physical activity promotion program and the remainder investigated structured exercise. Most interventions (86%) were more costly but more effective, and the remaining were cost-saving compared to no intervention.ConclusionsThere is a scarcity of reviews investigating the value for money of physical activity interventions for older adults. Most studies investigated structured exercise. Physical activity interventions were generally more effective than no intervention but more costly. As such an intervention could be cost-effective and therefore worthy of wider implementation, but there is a need for more frequent economic evaluation in this field.
IK-DDI: a novel framework based on instance position embedding and key external text for DDI extraction
Authors: Dou Mingliang , Ding Jiaqi , Chen Genlang , Duan Junwen , Guo Fei , Tang Jijun 
Published: March 2023

Abstract
Determining drug–drug interactions (DDIs) is an important part of pharmacovigilance and has a vital impact on public health. Compared with drug trials, obtaining DDI information from scientific articles is a faster and lower cost but still a highly credible approach. However, current DDI text extraction methods consider the instances generated from articles to be independent and ignore the potential connections between different instances in the same article or sentence. Effective use of external text data could improve prediction accuracy, but existing methods cannot extract key information from external data accurately and reasonably, resulting in low utilization of external data. In this study, we propose a DDI extraction framework, instance position embedding and key external text for DDI (IK-DDI), which adopts instance position embedding and key external text to extract DDI information. The proposed framework integrates the article-level and sentence-level position information of the instances into the model to strengthen the connections between instances generated from the same article or sentence. Moreover, we introduce a comprehensive similarity-matching method that uses string and word sense similarity to improve the matching accuracy between the target drug and external text. Furthermore, the key sentence search method is used to obtain key information from external data. Therefore, IK-DDI can make full use of the connection between instances and the information contained in external text data to improve the efficiency of DDI extraction. Experimental results show that IK-DDI outperforms existing methods on both macro-averaged and micro-averaged metrics, which suggests our method provides complete framework that can be used to extract relationships between biomedical entities and process external text data.
Scalable subsampling: computation, aggregation and inference
Authors: Politis Dimitris N 
Published: March 2023

AbstractSubsampling has seen a resurgence in the big data era where the standard, full-resample size bootstrap can be infeasible to compute. Nevertheless, even choosing a single random subsample of size b can be computationally challenging with both b and the sample size n being very large. This paper shows how a set of appropriately chosen, nonrandom subsamples can be used to conduct effective, and computationally feasible, subsampling distribution estimation. Furthermore, the same set of subsamples can be used to yield a procedure for subsampling aggregation, also known as subagging, that is scalable with big data. Interestingly, the scalable subagging estimator can be tuned to have the same, or better, rate of convergence than that of θ^n. Statistical inference could then be based on the scalable subagging estimator instead of the original θ^n.
Association between hearing sensitivity and dopamine transporter availability in Parkinson’s disease
Authors: Garasto Elena , Stefani Alessandro , Pierantozzi Mariangela , Cerroni Rocco , Conti Matteo , Maranesi Simone , Mercuri Nicola B , Chiaravalloti Agostino , Schillaci Orazio , Viziano Andrea , Moleti Arturo , Sisto Renata 
Published: March 2023

AbstractIn a previous study, we observed: (i) significant hearing function impairment, assessed with pure tone audiometry and distortion product otoacoustic emissions, in patients with Parkinson’s disease, compared with a matched control group, and (ii) lateralization of the hearing dysfunction, worse on the side affected by more pronounced Parkinson’s disease motor symptoms. This study investigates the association between the basal ganglia dopamine transporter availability and the hearing function in Parkinson’s disease patients, focusing also on the lateralization of both dysfunctions, with respect to that of the motor symptoms, and introducing a further distinction between patients with left-sided and right-sided predominant motor symptoms. Patients with right-handed Parkinson’s disease with a recent estimation of 123I-FP-CIT striatal uptake were audiologically tested with pure tone audiometry and distortion product otoacoustic emissions. Thirty-nine patients were included in the study. A statistically significant association was found, in the left-side predominant group only, between the distortion product otoacoustic emission levels and the contralateral dopamine transporter availability, and between the hearing threshold and the dopamine transporter availability difference between the ipsi- and the contralateral sides. The hearing impairment lateralization correlated to the motor symptom asymmetry was found significant only in the left-side predominant patients. The association between hearing function and basal ganglia dopamine transporter availability supports the hypothesis that the peripheral hearing function decline associated with dopamine depletion is involved in Parkinson’s disease development, with a significant difference between patients with left- and right-sided predominant motor symptoms. These findings also suggest that peripheral hearing function evaluation and its lateralization could be key elements for subtyping the disease.
Plasma glycocalyx pattern: a mirror of endothelial damage in chronic kidney disease
Authors: Valera Gemma , Figuer Andrea , Caro Jara , Yuste Claudia , Morales Enrique , Ceprián Noemí , Bodega Guillermo , Ramírez Rafael , Alique Matilde , Carracedo Julia 
Published: March 2023

ABSTRACT

Background
Endothelial damage and cardiovascular disease complicate chronic kidney disease (CKD). The increased atherogenicity observed in patients with CKD can be linked to microinflammation and endothelial damage. Circulating endothelial glycocalyx degradation products, such as perlecan and decorin, tend to be elevated in CKD. We aimed to explore the association between the plasma perlecan and decorin levels and this pro-inflammatory and atherogenic state by studying monocyte subpopulations and intracellular adhesion molecule (ICAM)-1 expression in patients with CKD.

Methods
We studied 17 healthy controls, 23 patients with advanced CKD, 25 patients on haemodialysis, 23 patients on peritoneal dialysis and 20 patients who underwent kidney transplantation. Perlecan and decorin levels were evaluated using enzyme-linked immunosorbent assays, and the monocyte phenotype was analysed using direct immunofluorescence and flow cytometry.

Results
The plasma perlecan levels were higher in patients with CKD than in the healthy controls. These levels were associated with a higher prevalence of ICAM-1+ monocytes. Conversely, patients with advanced CKD (pre-dialysis) had higher plasma decorin levels, which were associated with a reduced ICAM-1 expression per monocyte.

Conclusions
Elevated perlecan levels in CKD may be associated with a higher prevalence of ICAM-1+ monocytes and a pro-inflammatory phenotype. Elevated decorin levels may act as a negative regulator of ICAM-1 expression in monocytes. Therefore, perlecan and decorin may be related to inflammation and monocyte activation in CKD and may act as potential markers of endothelial damage.
CD-BCM:Cross-Domain Batch Certificates Management Based On Blockchain
Authors: Yao Shixiong , Li Pei , Chen Jing , Zeng Yuexing , Chen Jiageng , Wang Donghui 
Published: March 2023

Abstract
With the development of information networks, the entities from different network domains interact with each other more and more frequently. Therefore, identity management and authentication are essential in cross-domain setting. The traditional Public Key Infrastructure (PKI) architecture has some problems, including single point of failure, inefficient certificate revocation status management and also lack of privacy protection, which cannot meet the demand of cross-domain identity authentication. Blockchain is suitable for multi-participant collaboration in multi-trust domain scenarios. In this paper, a cross-domain certificate management scheme CD-BCM based on the consortium blockchain is proposed. For the issue of Certificate Authority’s single point of failure, we design a multi-signature algorithm. In addition, we propose a unified structure for batch certificates verification and conversion, which improve the efficiency of erroneous certificate identification. Finally, by comparing with current related schemes, our scheme achieves good functionality and scalability in the scenario of cross-domain certificate management.
Traffic-Aware Re-Grouping for Load Balance in IEEE 802.11ah IoT Network Based on the Registered Backoff Time Mechanism
Authors: Huang Chung-Ming , Huang Shu-Hang 
Published: March 2023

Abstract
IEEE 802.11ah, which is a wireless network protocol designed for Internet of Things (IoT), devised the Restrict Access Window (RAW) mechanism to tackle the collision problem. However, some RAW’s slots may be overloaded; some RAW’s slots may be lightly loaded or have no load because no stations (STA) allocated in these slots need to access channel. This work adopted (i) the Registered Backoff Time (RBT) mechanism such that each STA can register the backoff time for its future channel access in access point (AP) and (ii) the Claiming RAW mechanism such that STAs are allowed to notify AP that they have uplinked data to transmit. In this way, AP can (1) know which STAs have uplinked data to transmit and thus (2) re-schedule those STAs from the overloaded slots to the slots that (i) are underloaded or (ii) no STAs need to access channel based on STAs’ RBTs in advance. As a result, the proposed Registration-based Regrouping for Load-Balance Channel Access (RRG-LBCA) method can achieve load balance among slots to increase the IEEE 802.11ah network’s performance. The performance evaluation results shown that the proposed RRG-LBCA method can eliminate the collision situation and increase the aggregate throughput.
Browning of Mesenteric White Adipose Tissue in Crohn’s Disease: A New Pathological Change and Therapeutic Target
Authors: Zuo Lugen , Geng Zhijun , Song Xue , Li Jing , Wang Yueyue , Zhang Xiaofeng , Ge Sitang , Wang Lian , Liu Guangyong , Zhang Lele , Xu Mengyu , Zhao Yajing , Shen Li , Ge Yuanyuan , Wu Rong , Hu Jianguo 
Published: March 2023

Abstract

Backround
Hypertrophic mesenteric adipose tissue [htMAT] is a distinctive hallmark of Crohn’s disease [CD], and it affects enteritis via inflammatory adipokine secretion by dysfunctional white adipocytes. White adipocytes can become beige adipocytes, which are characterized by active lipid consumption and favourable endocrine function, via white adipocyte browning. Our study aimed to determine whether white adipocyte browning occurs in htMAT and its role in CD.

Methods
White adipocyte browning was examined in MAT samples from CD patients and controls. Human MAT explants and primary mesenteric adipocytes were cultured for in vitro experiments. Mice with 2,4,6-trinitrobenzenesulphonic acid solution [TNBS]-induced colitis were used for in vivo studies. A β3-adrenergic receptor agonist [CL316,243] was used to induce white adipocyte browning, and IL-4/STAT6 signalling was analysed to explore the mechanism underlying the anti-inflammatory activity of beige adipocytes.

Results
White adipocyte browning was observed in htMAT from CD patients, as shown by the appearance of uncoupling protein 1 [UCP1]-positive multilocular [beige] adipocytes with lipid-depleting activity and anti-inflammatory endocrine profiles. Both human MAT and primary mesenteric adipocytes from CD patients and controls could be induced to undergo browning, which increased their lipid-depleting and anti-inflammatory activities in vitro. Inducing MAT browning ameliorated mesenteric hypertrophy and inflammation as well as colitis in TNBS-treated mice in vivo. The anti-inflammatory activity of beige adipocytes was at least partially related to STAT6 signalling activation via the autocrine and paracrine effects of IL-4.

Conclusion
White adipocyte browning is a newly identified pathological change in htMAT of CD patients and a possible therapeutic target.
Evaluating the impact of at-plant termination of a cereal rye cover crop with different corn planting dates on arthropod activity
Authors: Inveninato Carmona Gabriela , McMechan Anthony Justin 
Published: March 2023

Abstract
Greater cover crop biomass is expected to result in a favorable microhabitat for beneficial arthropods. Natural Resources Conservation Service (NRCS) cover crop termination guidelines are based on the cash crop planting date. Therefore, a delay in cash crop planting could result in greater cover crop biomass. However, studies on delays in cash crop planting and greater cover crop biomass have led to a decrease in cash crop yield. Thus, a field study was conducted in eastern Nebraska over two years to evaluate the impact of early and late corn planting dates with at-plant cover crop terminations on pest potential, beneficial arthropod activity, and agronomic parameters. To measure arthropod activity and pests in the system, pitfall traps, and corn injury assessments were performed during the early stages of corn development. A total of 11,054 and 43,078 arthropods were collected in 2020 and 2021, respectively. The results have shown no impact of the corn planting dates with at-plant cover crop termination on arthropods but identified that cereal rye cover crop supports greater Araneae activity while its alternative prey varied when compared to the no-cover treatment. Significant yield penalties were observed when cover crop was used regardless of the corn planting dates. Pest pressure was not significant in any year, however, future research using cereal rye and different cover crop species should be used in this system with an artificial infestation of a pest to be able to evaluate the trade-offs between possible cash crop yield reductions and potential biological control of pests.
Life history parameters of Bemisia tabaci MED (Hemiptera: Aleyrodidae) in the present and future climate of central Europe, predicted by physically realistic climatic chamber simulation
Authors: Milenovic Milan , Eickermann Michael , Junk Jürgen , Rapisarda Carmelo 
Published: March 2023

Abstract
Whiteflies of the Bemisia tabaci species complex are among the most damaging insect pests in agriculture worldwide, causing damage by feeding on crop plants and by vectoring plant viruses. The species complex consists of over 35 cryptic species that differ in many aspects of their biology including the optimal environment, geographic distribution, and host range. Global warming and associated climate change resulting from human activities is expected to contribute to biological invasions. Bemisia tabaci species show fast adaptability to changes in agroecosystems and have a long record of biological invasions. Climate change driven increase in B. tabaci importance in agricultural systems of Europe has been predicted, but so far not experimentally tested. The present study evaluates the development of B. tabaci MED (=Mediterranean) in a climatic chamber simulation of the future climate in Luxembourg, chosen as a representative region for the Central Europe. Future climate predictions for the period 2061–2070 were derived from a multimodel ensemble of physically consistent regional climatic models. Results show a 40% shorter development time of this important pest in future climatic conditions, with an increase in fecundity by a third, and insignificant difference in mortality. Accelerated development, combined with its already established year-round presence in European greenhouses and predicted northward expansion of outdoor tomato production in Europe, means faster population build-up at the beginning of the outdoor cropping season with the potential of reaching economic importance. Benefits of simulating hourly diurnal cycle of physically consistent meteorological variables versus previous experiments are discussed.