bluuebunny/crossref_metadata_2025_split huggingface dataset:
A latent class analysis of the socio-demographic factors and associations with mental and behavioral disorders among Australian children and adolescents
Authors: Afroz Nahida , Kabir Enamul , Alam Khorshed 
Published: May 2023

Background
Previous studies have shown a relationship between socio-demographic variables and the mental health of children and adolescents. However, no research has been found on a model-based cluster analysis of socio-demographic characteristics with mental health. This study aimed to identify the cluster of the items representing the socio-demographic characteristics of Australian children and adolescents aged 11–17 years by using latent class analysis (LCA) and examining the associations with their mental health.

Methods
Children and adolescents aged 11–17 years (n = 3152) were considered from the 2013–2014 Young Minds Matter: The Second Australian Child and Adolescent Survey of Mental Health and Wellbeing. LCA was performed based on relevant socio-demographic factors from three levels. Due to the high prevalence of mental and behavioral disorders, the generalized linear model with log-link binomial family (log-binomial regression model) was used to examine the associations between identified classes, and the mental and behavioral disorders of children and adolescents.

Results
This study identified five classes based on various model selection criteria. Classes 1 and 4 presented the vulnerable class carrying the characteristics of “lowest socio-economic status and non-intact family structure” and “good socio-economic status and non-intact family structure” respectively. By contrast, class 5 indicated the most privileged class carrying the characteristics of “highest socio-economic status and intact family structure”. Results from the log-binomial regression model (unadjusted and adjusted models) showed that children and adolescents belonging to classes 1 and 4 were about 1.60 and 1.35 times more prevalent to be suffering from mental and behavioral disorders compared to their class 5 counterparts (95% CI of PR [prevalence ratio]: 1.41–1.82 for class 1; 95% CI of PR [prevalence ratio]: 1.16–1.57 for class 4). Although children and adolescents from class 4 belong to a socio-economically advantaged group and shared the lowest class membership (only 12.7%), the class had a greater prevalence (44.1%) of mental and behavioral disorders than did class 2 (“worst education and occupational attainment and intact family structure”) (35.2%) and class 3 (“average socio-economic status and intact family structure”) (32.9%).

Conclusions
Among the five latent classes, children and adolescents from classes 1 and 4 have a higher risk of developing mental and behavioral disorders. The findings suggest that health promotion and prevention as well as combating poverty are needed to improve mental health in particular among children and adolescents living in non-intact families and in families with a low socio-economic status.
High post-exposure prophylaxis (PEP) uptake among household contacts of pertussis patients enrolled in a PEP effectiveness evaluation – United States, 2015–2017
Authors: McNamara Lucy A. , Rubis Amy B. , Pawloski Lucia , Briere Elizabeth , Misegades Lara , Brusseau Aurora A. , Peña Sandra , Edge Karen , Wester Rachel , Burzlaff Kari , Cruz Victor , Tondella Lucia , Skoff Tami H. ,   for the Pertussis Post-Exposure Prophylaxis Study Team
Published: May 2023

BackgroundPost-exposure prophylaxis (PEP) for pertussis is recommended for household contacts of pertussis cases in the United States within 21 days of exposure, but data on PEP effectiveness for prevention of secondary cases in the setting of widespread pertussis vaccination are limited. We implemented a multi-state evaluation of azithromycin PEP use and effectiveness among household contacts.MethodsCulture- or PCR-confirmed pertussis cases were identified through surveillance. Household contacts were interviewed within 7 days of case report and again 14–21 days later. Interviewers collected information on exposure, demographics, vaccine history, prior pertussis diagnosis, underlying conditions, PEP receipt, pertussis symptoms, and pertussis testing. A subset of household contacts provided nasopharyngeal and blood specimens during interviews.ResultsOf 299 household contacts who completed both interviews, 12 (4%) reported not receiving PEP. There was no evidence of higher prevalence of cough or pertussis symptoms among contacts who did not receive PEP. Of 168 household contacts who provided at least one nasopharyngeal specimen, four (2.4%) were culture or PCR positive forB.pertussis; three of these received PEP prior to their positive test result. Of 156 contacts with serologic results, 14 (9%) had blood specimens that were positive for IgG anti-pertussis toxin (PT) antibodies; all had received PEP.ConclusionsVery high PEP uptake was observed among household contacts of pertussis patients. Although the number of contacts who did not receive PEP was small, there was no difference in prevalence of pertussis symptoms or positive laboratory results among these contacts compared with those who did receive PEP.
Síndrome de sotos: una mirada al gigantismo cerebral. Reporte de caso.
Authors: Redondo Meza Yulys Carolina , Lopez Garcia Teresa Josefina , Molina Toro John Carlos , Gordillo Gonzalez Gisel 
Published: May 2023

Antecedentes: El Síndrome de Sotos también conocido como Gigantismo cerebral. Es uno de los síndromes de sobrecrecimiento más frecuentes, La macrocefalia y alta estatura son características frecuentes de estos niños. Se caracteriza por una apariencia facial distintiva (frente amplia y prominente con una forma dolicocefalia, escaso cabello frontotemporal, entre otros); discapacidad en el aprendizaje y sobrecrecimiento corporal. El tratamiento va encaminado a favorecer el desarrollo neurológico. Caso clínico: se presenta el caso de un preescolar que en la etapa de lactante evidenció perímetro cefálico aumentado y pobre avance en el neurodesarrollo, con dolicocefalia, frente abombada, fisuras estrechas, columna hipoplásica, narinas apuntando hacia arriba, paladar íntegro, pabellones rotados posteriormente, espalda con cifosis importante lumbar. El estudio molecular, identificó una variante heterocigota, tipo missense c.5165G>C; p.Cys1722Ser en el gen NSD1. El paciente recibe acompañamiento multidisciplinar con avance en neurodesarrollo. Conclusión: A pesar de su distribución mundial, es posible que el síndrome de Sotos no se notifique. Además de su cuadro clínico característico, las pruebas genéticas moleculares también son muy recomendables para llegar al diagnóstico.
Dificultades de alimentación en pacientes con alergia alimentaria en gastroenterología pediátrica
Authors: Dadán Silvana , Daza Wilson , Higuera Carrillo Michelle 
Published: May 2023

Introducción: la alergia alimentaria es una respuesta inmunitaria anormal a un antígeno alimentario en la cual los pacientes pueden tener trastornos alimentarios secundarios a la respuesta inmune. Objetivos: describir las dificultades de alimentación en pacientes con alergia alimentaria en un centro de gastroenterología y nutrición en Bogotá D.C. Colombia.
Métodos: estudio retrospectivo. Se incluyeron pacientes de 0 a 18 años con diagnóstico de alergia alimentaria, durante el periodo 2013 a 2015. Para comparar las variables de interés, se utilizó la prueba de Fischer. Resultados: se incluyeron un total de 644 pacientes, de los cuales, 109 (16.92 %) presentaban alergia alimentaria y 40 casos (36.69 %) tenían algún tipo de dificultades de alimentación en la que la manifestación más frecuente fue alteración del apetito. Las dificultades de alimentación se presentaron en 62.5 % de los pacientes con alergia alimentaria mediada por mecanismo mixto (p <0.009). La expresión clínica más frecuente fue esofagitis eosinofílica (37.5 %), el apetito selectivo fue el síntoma más común. En los pacientes con alergia alimentaria sin dificultades de alimentación el mediado por inmunoglobulina E fue proporcionalmente mayor (52.17 %). Las dificultades de alimentación se encontraron con mayor frecuencia en varones (55 %) y lactantes (77.5 %) con una edad media de 13.3 meses. Más de la mitad de los pacientes con alergia alimentaria y dificultades de alimentación presentaban estado nutricional normal (55 %). Entre los antecedentes de importancia para las dificultades de alimentación se presentó: la hospitalización previa (52.5 %), la alimentación nasogástrica u orogástrica (15 %) e historia de prematuridad (5 %). Conclusiones: las dificultades de alimentación parecen presentarse más frecuentemente en alergia alimentaria de mecanismo mixto, y dentro de ellas, principalmente con la esofagitis eosinofílica. Las dificultades de alimentación en los pacientes con alergia alimentaria pueden orientar al médico y al nutricionista acerca de la necesidad de iniciar un manejo interdisciplinario y preventivo para evitar o minimizar las dificultades de alimentación y sus impactos.
Perfil epidemiológico de la mortalidad perinatal en el departamento del Cauca, Colombia, 2010- 2018.
Authors: Quiñonez Zúñiga Yenny Alexandra , Castro-Delgado Oscar Eduardo , Sotelo Daza Jorge Albeiro , Ortiz Martinez Roberth Alirio 
Published: May 2023

Introducción: la mortalidad perinatal es un grave problema de salud pública a nivel mundial. Se estima que el 98 % ocurren en los países en vías de desarrollo. En el Departamento del Cauca, Colombia, las tasas permanecen constantes e incluso superan las nacionales. Objetivo: determinar el perfil epidemiológico de mortalidad perinatal, en el Departamento del Cauca, entre los años 2010 a 2018. Métodos: Cohorte retrospectiva en el que se incluyeron todos los casos de mortalidad perinatal, registrados en la base de datos del Sistema de Vigilancia Epidemiológica Nacional, del Departamento del Cauca, del 2010 al 2018. El análisis se realizó en SPSS versión 19.0. Resultados: Se incluyeron 2.527 registros de muertes perinatales durante el período de estudio; 42.9 % de las madres con casos de muertes perinatales tenían entre 20 a 29 años; 80.61 % pertenecían al régimen subsidiado; 26.2 % de las madres eran indígenas; 42.50 % tenían un nivel educativo de secundaria; el 18 % de las madres tenían algún método de planificación familiar; 57 % hicieron menos de 4 controles prenatales y 64.51 % hicieron controles prenatales de manera tardía (después del primer trimestre de gestación). El 40.04 % de las muertes perinatales fueron secundarias a asfixia; 69.5% presentaron bajo peso al nacer (< 2500 gramos) y 69,9 % tenían edades gestacionales por debajo de las 37 semanas de gestación. El 55.5 % de los casos se presentó en el anteparto. Conclusiones: Las tasas de mortalidad perinatal en el Departamento del Cauca han permanecido constantes. Es más frecuente en madres afiliadas al régimen subsidiado, pertenecientes a algún grupo étnico, con bajo nivel educativo, con baja regulación de la fecundidad, antecedente de muerte fetal y con limitados controles prenatales.
EDTA-associated pseudothrombocytopenia: definition and real-world occurrence
Authors: Markewitz Robert , Sharifzadeh Shahpour Reza , Junker Ralf , Wandinger Klaus-Peter 
Published: May 2023

Abstract

Objectives
To better characterize occurrence and extent of anticoagulant-associated pseudothrombocytopenia (PTCP) in the daily routine of a high-throughput clinical laboratory in order to draw conclusions on a more precise definition of this phenomenon.

Methods
Concomitant platelet counts in both EDTA and citrate whole blood (WB) performed in our laboratory over a period of four years and 9 months, were analyzed, calculating the correlation, as well as the absolute difference in the results obtained from both materials, cross-referencing these measures with automated flags for platelet aggregates and the results of the visual examination for platelet aggregates of peripheral blood smears.

Results
Platelet counts in both materials were strongly correlated (ρ=0.86; p<0.0001) but are on average significantly higher in EDTA WB than in citrate WB (median difference: 11 ± 14.8/nL, p<0.0001). This is in spite of numerous instances of EDTA-associated PTCP recorded in our data, where the opposite is the case. The automated flag for possible platelet aggregates was shown to be very unspecific, while a machine-learning algorithm suggested the difference in platelet counts between EDTA and citrate WB as a predictor of platelet aggregates.

Conclusions
EDTA-associated PTCP is a regular occurrence. Differences in platelet counts between EDTA and citrate WB appear to be a far better predictor of PTCP than automated flags. A clear and useful definition of PTCP is still missing, however, and cannot be derived from our data either, indicating the need for further research.
Self-Respect and the Importance of Basic Liberties
Authors: Stensen Vegard 
Published: May 2023

Abstract
This article discusses the self-respect argument for basic liberties, which is that self-respect is an important good, best supported by basic liberties, and that this yields a reason for the traditional liberty principle. I concentrate on versions of it that contend that self-respect is best supported by basic liberties for reasons related to the recognition that such liberties convey. I first discuss the two standard approaches loosely associated with John Rawls and Axel Honneth. Here self-respect pertains to traits and conduct (Rawls) or to one’s personhood (Honneth). It is argued that these approaches fail to show why self-respect is better supported by the liberty principle than certain alternatives worth taking seriously – unless (in the case of personhood self-respect) self-respect is construed in such a narrow way that it is not a condition for autonomy or welfare in any plausible sense. I then identify a self-attitude that I call “a sense of competence”, which at least shows that the liberty principle is more important to autonomy than what we might otherwise have reasons to believe.
Flood Governance: A Review on Allocation of Flood Victims Using Location-Allocation Model and Disaster Management in Malaysia
Authors: Mah Hashim Noridayu , Abu Bakar Noor Akma , Kamaruzzaman Zetty Ain , Shariff Sarifah Radiah , Amin Burhanuddin Siti Nur Zahrah 
Published: May 2023

Flood management can be defined as the technique and strategy to reduce the risk and damage from flooding. The efficient strategies for the both short-term and long-term plans is needed in order to minimise losses and damage during disaster happen. Flood governance entails the need of a coordinated system in dealing with this natural disaster. The phases of the flood disaster management cycle such as flood preparedness, flood mitigation, Emergency Response Plan (ERP), and flood recovery helped the federal government and states government to overcome the flood disaster. In Malaysia, the disaster management undergoes three levels, where each level is governed by a committee with specified responsibilities. Flood disaster mitigation is crucial since it is possible to prevent damage that is brought upon by flood disaster. During the flood event, all the flood victims must be allocated to relief center. The allocation process needs to be conducted efficiently to avoid much worse incidents happening. The aims of this paper review are to explore the existing knowledge on flood mitigation and to identify Location-allocation model currently applied to solve allocation of flood victims to relief centre.The paper review is based on secondary data to give comparison and recommendation in achieving the objective. However, lack of coordination remains an issue that could potentially be tackled using a more efficient framework. Further researches are needed to test the effectiveness of this framework in improving flood governance.
Improving and Sustaining Interpreter Use Over 5 Years in a Pediatric Emergency Department
Authors: Hartford Emily A. , Rutman Lori E. , Fenstermacher Sara , Eaton Kathy , Ramos Jessica , Carlin Kristen , Lion K. Casey 
Published: May 2023

BACKGROUND
Patients with a language for care other than English (LOE) face communication barriers and inequitable outcomes in health care. Professional interpretation can improve outcomes but is underutilized. Our pediatric emergency department (ED) implemented quality improvement (QI) interventions over a 5-year period with an aim to increase interpreter use to 80% of patient encounters with LOE.

METHODS
Overall interpreter use for ED encounters was measured over time, with a baseline period of October 2015 to December 2016 and during 5 years of QI interventions from January 2017 to August 2021. Interventions included staff education, data feedback, reducing barriers to interpreter use, and improving identification of language for care with plan-do-study-act cycles. Outcomes were analyzed by using statistical process control charts and standard rules for special cause variation.

RESULTS
We analyzed a total of 277 309 ED encounters during the study period, 12.2% with LOE. The overall use of interpretation increased from a baseline of 53% to 82% of encounters. Interpretation throughout the ED visit and the number of interpreted interactions per hour also increased. There was improvement across language types, patient age groups, acuity levels, and during different times of day. Special cause variation was associated with multiple QI interventions.

CONCLUSION
We reached our primary aim of providing professional interpretation for 80% of patient encounters with LOE. There were several QI interventions associated with improvements, including staff education, data feedback, improved access to interpretation, and improved identification and visualization of language for care. Efforts to improve interpreter use may benefit from a similar multifaceted approach.
A prolegomenon to the study of the late antique casket of Traismauer (Augustianis)
Authors: Bianchi Davide 
Published: May 2023

AbstractThis paper offers an updated and current picture of the history of research carried out by scholars affiliated with Austrian universities and institutions on late antique caskets found in the territories of the provinces of Noricum and Pannonia. The central figure in this research was Helmut Buschhausen who, notably in his monograph on the subject, collected a large number of casket mounts found particularly in the Pannonian provinces. Starting with Buschhausen's research, this paper focuses on the evolution of studies carried out in Austria on late Roman caskets to define the status quaestionis, also in consideration of the research carried out in this area by Hungarian scholars. The description of an interesting case study concerning the casket mounts found at the Austrian site of Traismauer (Augustianis) allows us to take stock of current studies of late antique caskets.
A clinical analysis of ectopic pregnancies in a tertiary care centre: A one year retrospective study
Authors: Battu Gangajamuna , Tatikunta Vijayakrishna , Rameshwaram Priyadarshini 
Published: May 2023

Following fertilization and fallopian tube transit, the blastocyst normally implants in the endometrial lining of the uterine cavity. An ectopic pregnancy occurs when a fertilized ovum implants outside the normal uterine cavity. Fortunately, beta-human chorionic gonadotropin (β-hCG) assays and transvaginal sonography (TVS) aid earlier diagnosis, maternal survival, and fertility conservation. Ruptured ectopic is a surgical emergency.To study and analyse ectopic pregnancies in a tertiary care centre.To determine the incidence, risk factors, clinical presentation, management, morbidity and mortality of ectopic pregnancy.: A retrospective analysis of ectopic pregnancies was done in Gandhi hospital, Secunderabad from October 2021 to September 2022 (1 year duration) with a sample of 97 cases of suspected ectopic pregnancies observed and treated, out of total 11252 pregnant women admitted.The incidence of ectopic pregnancy was 8 per 1000(0.81%) pregnancies, majority between the age of 20-30yrs (87.5%) and in higher order pregnancies (3or&#62;3 pregnancies) (50.4%). Risk factors were multiparity (50.5%), h/o infertility treatment (12.3%), tubal sterilisation (7.2%). The typical triad of amenorrhoea, pain abdomen and bleeding p/v was observed in 69% of cases. In 16.4% cases the haemoglobin was &#60;7gm% at presentation. Among 97 suspected cases of ectopic pregnancies, 90(92.7%) cases were found to have ectopic pregnancy. 27.8% of cases were presented in class 2 or more haemorrhagic shock. 79% cases were ruptured ectopic pregnancies. Ampullary ectopic pregnancies were predominant(62.9%) followed by corneal (14.6%) &#62; fimbrial(13.4%) &#62; ovarian(4.4%)&#62; isthmus (2.2%). 2 women among 97 cases of suspected ectopic pregnancies were found to have Heterotopic pregnancy {tubal+intrauterine [missed abortion]}. Unilateral salpingectomy was done in 90.5% cases. Medical management was done successfully with single dose of methotrexate in 1 case. Blood transfusions were given in 69.9% cases. Post op wound complications were observed in 3.1% cases. Mortality is zero in present study.Clinicians should be aware of the fact that any women in reproductive age group presenting with pain in lower abdomen or vaginal bleeding, ectopic pregnancy should be suspected irrespective of presence or absence of amenorrhoea, whether or not she has undergone sterilization, because early diagnosis is critical in reducing maternal morbidity and mortality and improving treatment success rates.
Assessment of risk of malignancy index scoring and histopathological correlation in the diagnosis and management of adnexal mass
Authors: Uvajanani S S  , Maharajan S  , Indirani T V 
Published: May 2023

: Pathologies of adnexal masses are commonly benign. The malignant lesions of adnexa carries a very low five-year survival rate, and hence the early recognition need to be done. There is no single gold standard investigation for the diagnosis of the malignancy of the adnexa. Risk of Malignancy Index (RMI) scoring system, combines the Serum CA 125(U/ML), Ultrasound score (U) and the menopausal status(M).: To assess the efficiency of Risk of Malignancy Index-3 (RMI-3) scoring system in discriminating benign and malignant adnexal mass, for early detection and management of malignant ovarian mass.: This is a prospective, observational study, among 50 female patients above the age of 25 years, diagnosed with adnexal mass under the Department of obstetrics and gynaecology, Government Rajaji Hospital, affiliated to Madurai Medical College, Madurai.All the study participants were subjected to detailed history taking, thorough clinical examination, ultrasonogram of abdomen and pelvis, and markers such as CA 125. Risk of Malignancy Index was calculated and correlated with the histopathological (HPE) findings of the excised tumours. : When the cut off of RMI score for predicting malignancy is 149.2 which had a sensitivity of 79.2%, specificity of 92.3%, positive predictive value of 90.47%, negative predictive value of 82.78% and a diagnostic accuracy of 86.01%.: Risk of Malignancy Index score is a simple tool, with a good diagnostic accuracy, hence it can be used as good screening tool for identification of the malignant lesions from the adnexal mass.