bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of caregiver input and language experience on the production of coda laterals by English–Malay bilingual preschoolers in multi-accent Singapore
Authors: SIM Jasper Hong , POST Brechtje 
Published: July 2023

AbstractLinguistic input in multi-lingual/-cultural contexts is highly variable. We examined the production of English and Malay laterals by fourteen early bilingual preschoolers in Singapore who were exposed to several allophones of coda laterals: Malay caregivers use predominantly clear-l in English and Malay, but their English coda laterals can also be l-less (vocalised/deleted) and in formal contexts, velarised. Contrastingly, the English coda laterals of the Chinese majority are typically l-less. Findings show that English coda laterals were overall more likely to be l-less than Malay laterals like their caregivers’, but English coda laterals produced by children with close Chinese peer(s) were more likely to be l-less than those without. All children produced English coda clear-l, demonstrating the transmission of an ethnic marker that had emerged from long-term contact. In diverse settings, variation is intrinsic to the acquisition process, and input properties and language experience are important considerations in predicting language outcomes.
Ideology and Party Positions on Gender Issues in Spain: Evidence from a Novel Data Set
Authors: Cabeza Pérez Laura , Alonso Sáenz de Oger Sonia , Gómez Fortes Braulio 
Published: July 2023

AbstractThis article introduces new quantitative fine-tuned indicators to objectively measure political parties’ preferences on gender issues. We assess the validity and reliability of these new empirical indicators by analyzing the relationship between ideology and gender positions in decentralized Spain. Using data collected by the Regional Manifestos Project, which for the first time has incorporated a fully fledged gender domain into its coding scheme for content analysis of regional manifestos, we analyze parties’ gender positions on four fundamental dimensions: welfare and the labor market, violence, representation, and values and identity. The results suggest that there is a persistent left-right divide on the last three dimensions: Spanish left-wing parties score significantly higher than right-wing and regionalist parties. However, ideology does not drive parties’ gender positions on welfare and labor market policies; support for gender equality policies on this dimension is so widespread that it can be considered a “valence issue”—all parties, irrespective of their ideology, endorse the same (positive) position.
A Customized Multi‐Scale Deep Learning Framework for Storm Nowcasting
Authors: Yang Shangshang , Yuan Huiling 
Published: July 2023

AbstractStorm nowcasting is critical and urgently needed. Recent advances in deep learning (DL) have shown potential for improving nowcasting accuracy and predicting general low‐intensity precipitation events. However, DL models yield poor performance on high‐impact storms due to insufficient extraction and characterization of complex multi‐scale spatiotemporal variations of storms. To tackle this challenge, we propose a novel customized multi‐scale (CM) DL framework, including a flexible attention module capturing scale variations and a customized loss function ensuring multi‐scale spatiotemporal consistency. The CM framework was applied to the storm event imagery data set (SEVIR). Representative cases indicate that the CM framework preserves the shape of storms and adequately forecasts intense storms even for longer predictions. The quantitative evaluation shows that all models applying our framework can improve skill scores by 8.5%–42.6% for 1‐hr nowcasting. This work highlights the importance of modeling multi‐scale spatiotemporal characteristics of meteorological variables when using DL.
The moderating role of recreational substance use in the association of Mediterranean diet with academic performance among adolescents
Authors: López-Gil José Francisco , Smith Lee , Gaya Anelise Reis , Victoria-Montesinos Desirée , Gutiérrez-Espinoza Héctor , Herrera-Gutiérrez Eva , García-Hermoso Antonio 
Published: July 2023

AbstractNo study has examined the potential moderating role of recreational substance use in the relationship between the Mediterranean diet (MedDiet) and academic performance. The aim of this study was to test the potential moderating role of recreational substance use (i.e., alcohol, tobacco, and cannabis) in the association of adherence to the MedDiet with academic performance among adolescents. This cross-sectional study included a sample of 757 adolescents (55.6% girls) aged 12–17 years from the Valle de Ricote (Region of Murcia). The Region of Murcia is an autonomous community of Spain located in the southeast of the Iberian Peninsula, along the coast of the Mediterranean Sea. Adherence to the MedDiet was assessed by the Mediterranean Diet Quality Index for Children and Teenagers (KIDMED). Recreational substance use (i.e., tobacco, alcohol, cannabis) was self-reported by adolescents. Academic performance was assessed by the school records at the end of the academic year. The relationship between adherence to the MedDiet and academic performance was moderated by both tobacco and alcohol use (for grade point average and all school records). In conclusion, higher adherence to the MedDiet was related to greater academic performance in adolescents, but recreational substance use could moderate this association.
On the possibility of using waste disposable gloves as recycled fibers in sustainable 3D concrete printing using different additives
Authors: Mousavi Seyed Sina , Dehestani Mehdi 
Published: July 2023

AbstractDue to the Covid-19 pandemic, using large amounts of personal protective equipment (PPE) throughout the world has extensively increased in recent years. The lack of a practical method to dispose of these recycled materials is one of the main concerns of researchers. Hence, comprehensive experimental tests were conducted in the present study to investigate the feasibility of using disposable gloves in mortars to achieve a sustainable mixture. Accordingly, latex and vinyl gloves as recycled fibers were considered in the experimental program to improve the sustainability of 3D printing concrete. As using these recycled materials causes some deficiencies for printing layers, different mineral and chemical admixtures were used in the present study, including graphene oxide nanomaterials, polyvinyl alcohol, Cloisite 15A nanoclay, and micro silica fume. Also, the hybrid use of latex, vinyl, and polypropylene (PP) fiber was considered to improve the printability of concrete mixtures containing waste fibers. Moreover, the effect of internal reinforcement was also considered by using plain steel wire mesh to increase the composite behavior of printed layers in this simplified experimental program. Results indicate that the synergic influence of recycled fibers and admixtures meaningfully enhanced the 3D printing properties of mortar so that about 20%, 80%, 50%, and more than 100% improvements were obtained for workability, direct tensile strength, flexural strength, and buildability index respectively. However, an average percentage − 28.3% reduction was recorded for the concrete compressive strength. Sustainability analysis also showed that using waste disposable gloves considerably reduced CO2 emissions.
Survival impact of microsatellite instability in stage II gastric cancer patients who received S-1 adjuvant monotherapy after curative resection
Authors: Sato Chihiro , Kawakami Hisato , Tanaka Ryo , Satake Hironaga , Inoue Kentaro , Kimura Yutaka , Fujita Junya , Kawabata Ryohei , Chiba Yasutaka , Satoh Taroh , Nakagawa Kazuhiko 
Published: July 2023

AbstractAdjuvant S-1 monotherapy is the standard of care for stage II gastric cancer (GC) after curative resection in Japan, but its efficacy for microsatellite instability–high (MSI-H) tumors has remained unknown. Among a multi-institutional cohort of patients with stage II GC who underwent R0 resection followed by S-1 adjuvant chemotherapy between February 2008 and December 2018, we assessed MSI status with an MSI-IVD Kit (Falco). MSI status was assessable for 184 (88.5%) of the 208 enrolled patients, with MSI-H being identified in 24 (13.0%) individuals. Although neither relapse-free survival (RFS) (hazard ratio [HR] = 1.00, p = 0.997) nor overall survival (OS) (HR = 0.66, p = 0.488) differed between MSI-H versus microsatellite-stable (MSS) patients, MSI-H patients showed a nonsignificant but better RFS (HR = 0.34, p = 0.064) and OS (HR = 0.22, p = 0.057) than did MSS patients after adjustment for background characteristics by propensity score (PS) analysis. Gene expression analysis in the PS-matched cohort suggested that recurrence was associated with the immunosuppressive microenvironment in MSI-H tumors but with expression of cancer/testis antigen genes in MSS tumors. Our data reveal a better adjusted survival for MSI-H versus MSS stage II GC treated with S-1 adjuvant therapy, and they suggest that mechanisms of recurrence differ between MSI-H and MSS tumors.
Orientational dynamics and rheology of active suspensions in weakly viscoelastic flows
Authors: Choudhary Akash , Nambiar Sankalp , Stark Holger 
Published: July 2023

AbstractMicroswimmer suspensions in Newtonian fluids exhibit unusual macroscale properties, such as a superfluidic behavior, which can be harnessed to perform work at microscopic scales. Since most biological fluids are non-Newtonian, here we study the rheology of a microswimmer suspension in a weakly viscoelastic shear flow. At the individual level, we find that the viscoelastic stresses generated by activity substantially modify the Jeffery orbits well-known from Newtonian fluids. The orientational dynamics depends on the swimmer type; especially pushers can resist flow-induced rotation and align at an angle with the flow. To analyze its impact on bulk rheology, we study a dilute microswimmer suspension in the presence of random tumbling and rotational diffusion. Strikingly, swimmer activity and its elastic response in polymeric fluids alter the orientational distribution and substantially amplify the swimmer-induced viscosity. This suggests that pusher suspensions reach the superfluidic regime at lower volume fractions compared to a Newtonian fluid with identical viscosity.
Time-variations of the climate feedback parameter λ are associated with the Pacific Decadal Oscillation
Authors: Meyssignac Benoît , Chenal Jonathan , Loeb Norman , Guillaume-Castel Robin , Ribes Aurélien 
Published: July 2023

AbstractClimate models suggest that the climate feedback parameter λ, which denotes the magnitude of the Earth radiative response to a change in global surface temperature, varies with time. This is because λ depends on the pattern of sea-surface temperature. However, the time-variability of λ and its relation to the sea-surface temperature pattern has not been evaluated in multi-decadal observations. Here, using up-to-date observations, we evaluate the global energy budget over successive 25-year windows and derive a time-series of λ over 1970–2005. We find λ varied within the range [−3.2, −1.0]W ⋅ m−2 ⋅ K−1 since 1970. These variations are linked to the sea-surface temperature pattern changes associated with the Pacific Decadal Oscillation. Climate model simulations forced with observations of historical sea-surface temperature show a 1970–2005 mean λ that is consistent with observations. However, they fail in reproducing observed λ time-variations since 1970 which are associated to the Pacific Decadal Oscillation, meaning that climate models underestimate the pattern effect at decadal time scales.
N-Acylsulfonamide: a valuable moiety to design new sulfa drug analogues
Authors: Amador Romain , Tahrioui Ali , Barreau Magalie , Lesouhaitier Olivier , Smietana Michael , Clavé Guillaume 
Published: July 2023

We report here the synthesis and antibacterial/antibiofilm activities of 18 sulfa drug analogues with an N-acylsulfonamide moiety obtained efficiently by sulfo-click reactions between readily available thioacid and sulfonyl azide synthons.
A Novel Narendra‐based adaptive anti‐disturbance control strategy for the microgrid inverters: A novel MG VSI adaptive anti‐disturbance control strategy based on Narendra theory
Authors: Shi HongTao , He Zhuoheng , Chang Jiaming , He Zhu , Feng Kun , Li Yuchao 
Published: July 2023

AbstractThe control performance of the voltage source inverter will be reduced when it operates under complex microgrid (MG) conditions. Traditionally, problems such as high controller order and complex design may occur when robust control and secondary regulation are adopted for the inverters. Meanwhile, when the conventional adaptive control is adopted, the adaptive gain may be too high, resulting in increased sensitivity of the system to external disturbances. To address the above problems, a novel Narendra‐based adaptive anti‐disturbance control strategy for microgrid voltage source inverter is proposed in this paper. Firstly, a Narendra adaptive‐based controller is constructed, which enables the controller to adaptively adjust the system parameters to change the inverter output voltage quality. Secondly, the extended state observer (ESO) is introduced to observe and suppress the total disturbance of the system, which can make the system less sensitive and ensure the stability of the system operation. Thirdly, according to the Lyapunov stability theory, the Lyapunov function is chosen to prove the global asymptotic stability of the system, and an adaptive law is designed. Finally, the comparative experiment shows that the proposed control strategy based on Narendra adaptive anti‐disturbance can maintain excellent voltage control performance in complex working conditions, and then ensure that the inverter's output voltage always meets power quality standard in complex working conditions.
Was wissen Sie über … Augen?
Authors: Schmid Eva C. 
Published: July 2023

SummaryLiebe Leser, testen Sie Ihr Wissen und frischen Sie Ihre Kenntnisse auf. Bitte kreuzen Sie jeweils eine Antwort an. Viel Spaß beim Beantworten wünscht Ihnen HP Eva C. Schmid!
Das Rezept aus dem Auge
Authors: Kropf Petra 
Published: July 2023

SummaryEine gründliche Irisanalyse liefert wertvolle Hinweise und Hintergründe zu Konstitution, Disposition und Diathese der Patienten. Die Informationen aus dem Auge in Verbindung mit der aktuellen Symptomatik ermöglichen es, individuelle Präventions- und Therapiekonzepte zu erstellen. Die geschilderten Fallbeispiele aus der Praxis stellen den Weg vom Erkennen der Zeichen bis zur therapeutischen Umsetzung dar.
Die Krausenzone im Blick
Authors: Bastian Petra 
Published: July 2023

SummaryIm Fokus steht der Magen-Darm-Trakt, der iridologisch in der Krausenzone lokalisiert ist. Zeichen wie Krypten, Pigmente, Stauungszeichen, Radiären etc. in der Magen-Darm-Zone können auf eine Tendenz zu entsprechenden Erkrankungen hinweisen. Anhand von 2 Fallbeispielen demonstriert die Autorin, welche Rolle der Magen-Darm-Trakt für multiple Beschwerden, aber auch die mentale Gesundheit von Patienten spielen kann.
Direct Organocatalytic Asymmetric para C–H Aminoalkylation of Aniline Derivatives Affording Diarylmethylamines
Authors: Wang Cheng-Long , Li Yong-Ling , Ding Tong-Mei , Sun Zhen-Liang , Wang Le , Wang Xun-Hui , Zhou Jia , Bai He-Yuan 
Published: July 2023

AbstractAn efficient method to directly catalyze asymmetric para C–H aminoalkylation of aniline derivatives to prepare chiral diarylmethylamine system was developed. Aniline derivatives underwent an enantioselective aminoalkylation in the presence of chiral phosphoric acid, affording a series of optically active diarylmethylamine products in good yields and enantioselectivities (73% yield, 91% ee). Furthermore, this method could be used to prepare the key intermediate of chiral drug levocetirizine.
Construction of an Epoxy-lactone Moiety on the C/D Ring of Highly Oxygenated Triterpenes through a Modified SeO2-Promoted Oxidative Cyclization
Authors: Chen Yang , Li Qiao-Yue , Wang Wen-Jing , Shao Li-Dong , Xie Xiao-Yan , Wang Wei , Li Dashan 
Published: July 2023

AbstractWe present herein a synthetic endeavor to prepare the epoxy-lactone moiety commonly present in the C/D ring of highly oxygenated triterpenes. Two strategies are applied starting from ursolic acid­: (i) Br+-promoted cyclization–isomerization for late-stage epoxidation, and (ii) one-step SeO2-promoted oxidative cyclization. Additionally, the desired epoxy-lactone moiety can be readily prepared on gram scale in one step by using the modified SeO2/TBHP/AcOH oxidative system.
Efficient Synthesis of Diethyl, Dialkyl α-Hydroxy-propylenebisphosphonates and Related 5-Phosphonoyl-1,2-oxaphospholane 2-Oxides
Authors: Keglevich György , Varga Petra Regina , Belovics Alexandra , Karaghiosoff Konstantin , Szabó Rita , Bősze Szilvia , Drahos László 
Published: July 2023

AbstractA series of new dialkyl α-diethylphosphonoylethyl-α-hydroxy-ethylphosphonates were prepared using the Pudovik reaction of the corresponding γ-oxophosphonate with dialkyl phosphites performed on the surface of Al2O3/KF. The adducts revealed unexpected reactivity in the attempted O-acylation reaction, and provided the corresponding 5-phosphonoyl-1,2-oxaphospholane 2-oxides. On treatment with Cs2CO3, instead of the expected rearrangement a cyclization reaction leading to the same ring products took place. Three of the phosphonoylethyl-α hydroxy-ethylphosphonates, along with two phosphonoylmethyl analogues revealed significant and selective anticancer effect on A431 cells, and occasionally, on PC-3 and MDA-MB 231 cells.
Cyanation and Hydrolysis Cascade of Aryl Bromides with Cuprous Cyanide to Access Primary Amides
Authors: Xia Chunnian , Hong Bo , Chen Xiaolin , Dai Jiawei , Gao Feng , Wang Ning , Wang Junfeng , Xiao Xiao , Dai Fengli , Li Yifang 
Published: July 2023

AbstractA convenient and efficient approach for the cyanation and hydrolysis of aryl bromides to afford primary amides was developed, in which cuprous cyanide is used as a cyanide source and a catalyst. It has the advantages of excellent functional-group compatibility, medium to high yields, a one-pot procedure, and a non-noble-metal catalyst. The reaction could be performed on a gram scale to give N-allyl-N-methyl-5-nitroisophthalamide in a 73% yield.
The brain-gut-microbiota axis in the treatment of neurologic and psychiatric disorders
Authors: Naufel Maria Fernanda , Truzzi Giselle de Martin , Ferreira Caroline Marcantonio , Coelho Fernando Morgadinho Santos 
Published: July 2023

AbstractThe human gut microbiota is a complex ecosystem made of trillions of microorganisms. The composition can be affected by diet, metabolism, age, geography, stress, seasons, temperature, sleep, and medications. The increasing evidence about the existence of a close and bi-directional correlation between the gut microbiota and the brain indicates that intestinal imbalance may play a vital role in the development, function, and disorders of the central nervous system. The mechanisms of interaction between the gut-microbiota on neuronal activity are widely discussed. Several potential pathways are involved with the brain-gut-microbiota axis, including the vagus nerve, endocrine, immune, and biochemical pathways. Gut dysbiosis has been linked to neurological disorders in different ways that involve activation of the hypothalamic-pituitary-adrenal axis, imbalance in neurotransmitter release, systemic inflammation, and increase in the permeability of the intestinal and the blood-brain barrier. Mental and neurological diseases have become more prevalent during the coronavirus disease 2019pandemic and are an essential issue in public health globally. Understanding the importance of diagnosing, preventing, and treating dysbiosis is critical because gut microbial imbalance is a significant risk factor for these disorders. This review summarizes evidence demonstrating the influence of gut dysbiosis on mental and neurological disorders.
COVID-19 in the nervous system: physiopathology and neurological manifestations
Authors: Mendonça Filho Valder Cavalcante Maia , de Oliveira Amanda Gomes , Maia Isabelle de Fátima Vieira Camelo , de Falcone Ananda Carolina Moraes , Betini Beatriz Gioppo , Rezende Lucas Bruno , Magri Alves Fernando Henrique 
Published: July 2023

AbstractBackground Coronavirus disease 2019 (COVID-19) is a viral infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although respiratory manifestations have received greater visibility during the pandemic caused by this virus, numerous neurological complaints related to coronavirus 2 infection have been documented in several countries. These records suggest that this pathogen presents neurotropism, and it can cause different neurological conditions of varying intensity.Objective To investigate the ability of coronavirus 2 to invade the central nervous system (CNS) and its neurological clinical outcomes.Methods The present study consists in a comprehensive literature review of the records available in the PubMed, SciELO, and Google Scholar databases. The descriptors COVID-19, brain and physiopathology, associated with the Boolean operator AND, were used in the search. Regarding the inclusion and exclusion criteria, we selected the papers published since 2020 with the highest number of citations.Results We selected 41 articles, most of them in English. The main clinical manifestation associated with COVID-19 patients was headache, but cases of anosmia, hyposmia, Guillain-Barré syndrome, and encephalopathies were also described with considerable frequency.Conclusion Coronavirus-2 presents neurotropism, and it can reach the CNS by hematogenous dissemination and by direct infection of the nerve endings. It causes brain injuries through several mechanisms, such as cytokine storm, microglial activation, and an increase in thrombotic factors.
Nasal Sill Flap for Lip Lifting
Authors: Uyar Ilker , Aksam Ersin , Kopal Can 
Published: July 2023

Abstract
Background Over the years, different techniques have been developed to reduce the number of incisions and scars in subnasal lip lifting and to increase the amount of lifting. The aim of this study was to present a new technique to hide the scars at the nasal base in subnasal lip lifting procedures and to review the literature.
Methods The file of patients who underwent subnasal lip lifting between January 2019 and January 2021 were examined. In all patients, the nasal sill flap that was designed was elevated, and the nasal sill flap that was prepared was adapted to its new location when the excision had been completed. Two different plastic surgeons evaluated the patients in the postoperative 12-month follow-ups. The scars were evaluated for vascularity, pigmentation, elasticity, thickness, and height.
Results The study included 26 patients. While 21 patients had no histories of lip lifting, five patients had had previous lip lifting history. The mean operation time was 37.11 minutes. Patients' skin types were determined as Type 3 in 18 patients and Type 4 in eight patients according to the Fitzpatrick classification. The mean follow-up period of the patients was 13.11 months. At the end of the 12-month period, the mean scar score of the patients was calculated as 11.15. The mean scar score of primary cases was 11.14, and the mean scar score of secondary cases was 11.20 (p = 0.983). There was no statistically significant difference in terms of complications among smokers (p = 0.356). The mean scar score was calculated as 12.17 in patients who had Type 3 skin and 8.88 in patients with Type 4 skin (p = 0.075).
Conclusions This technique is beneficial for patients because the scars are discrete and easier for patients to accept.