bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of mechanical properties and host tissue response to OviTex™ and Strattice™ surgical meshes
Authors: Lombardi J. , Stec E. , Edwards M. , Connell T. , Sandor M. 
Published: April 2023

Abstract
Purpose
This study compared the in vitro/benchtop and in vivo mechanical properties and host biologic response to ovine rumen-derived/polymer mesh hybrid OviTex™ with porcine-derived acellular dermal matrix Strattice™ Firm.

Methods
OviTex 2S Resorbable (OviTex 2S-R) and Strattice morphology were examined in vitro using histology and scanning electron microscopy; mechanical properties were assessed via tensile test; in vivo host biologic response and explant mechanics were evaluated in a rodent subcutaneous model. Separately, OviTex 1S Permanent (OviTex 1S-P) and Strattice were evaluated in a primate abdominal wall repair model.

Results
OviTex 2S-R demonstrated layer separation, whereas Strattice retained its structural integrity and demonstrated higher maximum load than OviTex 2S-R out-of-package (124.8 ± 11.1 N/cm vs 37.9 ± 5.5 N/cm, p < 0.001), 24 h (55.7 ± 7.4 N/cm vs 5.6 ± 3.8 N/cm, p < 0.001), 48 h (45.3 ± 14.8 N/cm vs 2.8 ± 2.6 N/cm, p = 0.003), and 72 h (29.2 ± 10.5 N/cm vs 3.2 ± 3.1 N/cm, p = 0.006) following collagenase digestion. In rodents, inflammatory cell infiltration was observed between OviTex 2S-R layers, while Strattice induced a minimal inflammatory response. Strattice retained higher maximum load at 3 (46.3 ± 27.4 N/cm vs 9.5 ± 3.2 N/cm, p = 0.041) and 6 weeks (28.6 ± 14.1 N/cm vs 7.0 ± 3.0 N/cm, p = 0.029). In primates, OviTex 1S-P exhibited loss of composite mesh integrity whereas Strattice integrated into host tissue with minimal inflammation and retained higher maximum load at 1 month than OviTex 1S-P (66.8 ± 43.4 N/cm vs 9.6 ± 4.4 N/cm; p = 0.151).

Conclusions
Strattice retained greater mechanical strength as shown by lower susceptibility to collagenase degradation than OviTex 2S-R in vitro, as well as higher maximum load and improved host biologic response than OviTex 2S-R in rodents and OviTex 1S-P in primates.
Predicting the risk of saltwater contamination of freshwater aquifers during aquifer thermal energy storage
Authors: Regnier G. , Salinas P. , Jackson M. D. 
Published: April 2023

AbstractAquifer thermal energy storage (ATES) is an underground thermal energy storage technology with a large potential to decarbonise the heating and cooling of buildings. ATES installations typically store thermal energy in aquifers that are also exploited for potable water, so a major consideration during development is ensuring that system operation will not lead to groundwater pollution. In this study, the risk of contamination due to upconing of a shallow freshwater/saltwater interface during ATES operation is investigated. Fluid flow, and heat and salt (chloride ion) transport are simulated in a homogeneous aquifer during ATES operation via a well doublet. The impact of geological, hydrological and operational parameters is investigated in a sensitivity analysis. Two new dimensionless numbers are proposed to characterise salt upconing and redistribution during ATES operation and provide a close match to simulated concentrations: CR,w characterises the contamination risk at the ATES installation, and CR,d characterises the risk at locations downstream of the ATES installation with respect to background groundwater flow. ATES systems with CR,w and CR,d < 10 introduce low risk of contamination in a homogenous aquifer, with chloride concentration at, and downstream of, the ATES system, remaining below the World Health Organisation’s advised limit. ATES installations with CR,w and CR,d > 10 cause a rapid increase in aquifer chloride concentration. The results are used to estimate an exclusion distance beyond which ATES system operation will not cause contamination in a homogenous aquifer. The dimensionless parameters proposed allow rapid assessment of the potential for saltwater contamination during ATES operation.
A waste wet oxidation technique as a solution for chemical production and resource recovery in Poland
Authors: Mumtaz Hamza , Werle Sebastian , Sobek Szymon 
Published: April 2023

AbstractEffective municipal solid waste (MSW) management and waste-to-resource recovery has a key potential to play a vital role in economic growth of a country. MSW contains the different items of daily use that makes its composition mix in nature. Different waste-to-energy techniques are already available to treat this waste but these techniques always require some pretreatments such pre-separation and pre-drying of mix MSW that makes these processes less techno-economic to apply on large scales. To provide an effective solution to this problem, potential wet oxidation technique has been reviewed in this study. In the first section, the statistics for MSW generation and composition for different cities in Poland have been presented to show the existence of maximum organic content which can be converted to useful organic compounds. In the later section, the wet oxidation technique and its various aspects have been reviewed in detail to justify the potential of this technique to treat mix MSW at larger scales to produce different valuable products in the context of waste-to-resource recovery.
Graphical abstract
Interobserver agreement on landmark and flexure identification in colon capsule endoscopy
Authors: Schelde-Olesen B. , Bjørsum-Meyer T. , Koulaouzidis A. , Buijs M. M. , Herp J. , Kaalby L. , Baatrup G. , Deding U. 
Published: April 2023

Abstract
Purpose
When an optical colonoscopy is carried out, Scope Guide can assist the endoscopist in determining the localization. In colon capsule endoscopy (CCE), this support is not available. To our knowledge, the interobserver agreement on landmark identification has never been studied. This study aims to investigate the interobserver agreement on landmark identification in CCE.

Methods
An interobserver study was carried out comparing the landmark identification (the ileocecal valve, hepatic flexure, splenic flexure, and anus) in CCE investigations between an external private contractor and three in-house CCE readers with different levels of experience. All CCE investigations analyzed in this study were carried out as a part of the Danish screening program for colorectal cancer. Patients were between 50 and 74 years old with a positive fecal immunochemical test (FIT). A random sample of 20 CCE investigations was taken from the total sample of more than 800 videos.

Results
Overall interobserver agreement on all landmarks was 51%. Interobserver agreement on the first cecal image (ileocecal valve), hepatic flexure, splenic flexure, and last rectal image (anus) was 72%, 29%, 22%, and 83%, respectively. The overall interobserver agreement, including only examinations with adequate bowel preparation (n = 16), was 54%, and for individual landmarks, 73%, 32%, 24%, and 85%.

Conclusion
Overall interobserver agreement on all four landmarks from CCE was poor. Measures are needed to improve landmark identification in CCE investigations. Artificial intelligence could be a possible solution to this problem.
Germany’s journey toward 14 Tesla human magnetic resonance
Authors: Ladd Mark E. , Quick Harald H. , Speck Oliver , Bock Michael , Doerfler Arnd , Forsting Michael , Hennig Jürgen , Ittermann Bernd , Möller Harald E. , Nagel Armin M. , Niendorf Thoralf , Remy Stefan , Schaeffter Tobias , Scheffler Klaus , Schlemmer Heinz-Peter , Schmitter Sebastian , Schreiber Laura , Shah N. Jon , Stöcker Tony , Uder Michael , Villringer Arno , Weiskopf Nikolaus , Zaiss Moritz , Zaitsev Maxim 
Published: April 2023

AbstractMultiple sites within Germany operate human MRI systems with magnetic fields either at 7 Tesla or 9.4 Tesla. In 2013, these sites formed a network to facilitate and harmonize the research being conducted at the different sites and make this technology available to a larger community of researchers and clinicians not only within Germany, but also worldwide. The German Ultrahigh Field Imaging (GUFI) network has defined a strategic goal to establish a 14 Tesla whole-body human MRI system as a national research resource in Germany as the next progression in magnetic field strength. This paper summarizes the history of this initiative, the current status, the motivation for pursuing MR imaging and spectroscopy at such a high magnetic field strength, and the technical and funding challenges involved. It focuses on the scientific and science policy process from the perspective in Germany, and is not intended to be a comprehensive systematic review of the benefits and technical challenges of higher field strengths.
The Pie of Inspiration: Positioning the Therapist’s and Client’s Knowledge in Solution-Focused Brief Therapy
Authors: Zatloukal Leoš 
Published: April 2023

AbstractNon-expert stance or “not-knowing” position plays important role in postmodern/ poststructuralist therapies (Tarragona, 2008) and at the same time many misunderstandings and potential pitfalls for therapeutic practice arose with this concept. This paper examines “knowledge” in therapeutic conversations from the perspective of one of the postmodern therapies – Solution-Focused Brief Therapy. After an introduction to the Solution-Focused Brief Therapy and its principles, attention is given to process and content related expertise and the solution-focused therapist’s positioning in conversations. The next section describes a model, called the Pie of Inspiration, which allows for reflecting on different sources of knowledge and inviting them into the solution-focused therapeutic conversation. The application of the model is illustrated through some case examples and an activity for working with children which is called Klondike.
Testing the post-Newtonian expansion with GW170817
Authors: Shoom Andrey A. , Gupta Pawan K. , Krishnan Badri , Nielsen Alex B. , Capano Collin D. 
Published: April 2023

AbstractObservations of gravitational waves from compact binary mergers have enabled unique tests of general relativity in the dynamical and non-linear regimes. One of the most important such tests is constraints on the post-Newtonian (PN) corrections to the phase of the gravitational wave signal. The values of the PN coefficients can be calculated within standard general relativity, and these values are different in many alternate theories of gravity. It is clearly of great interest to constrain the deviations based on gravitational wave observations. In the majority of such tests which have been carried out, and which yield by far the most stringent constraints, it is common to vary these PN coefficients individually. While this might in principle be useful for detecting certain deviations from standard general relativity, it is a serious limitation. For example, we would expect alternate theories of gravity to generically have additional parameters. The corrections to the PN coefficients would be expected to depend on these additional non-GR parameters, whence, we expect that the various PN coefficients to be highly correlated. We present an alternate analysis here using data from the binary neutron star coalescence GW170817. Our analysis uses an appropriate linear combination of non-GR parameters that represent absolute deviations from the corresponding post-Newtonian inspiral coefficients in the TaylorF2 approximant phase. These combinations represent uncorrelated non-GR parameters which correspond to principal directions of their covariance matrix in the parameter subspace. Our results illustrate good agreement with GR. In particular, the integral non-GR phase is $$\Psi _{{\tiny int-non-GR}} = 0.0447\pm 25.3000$$

Ψ

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n
t
-
n
o
n
-
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0.0447
±
25.3000

and the deviation from GR percentile is $$p^{{\tiny Dev-GR}}_{n}=25.85\%$$

p
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e
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-
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=
25.85
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.
Conditions for Successful Learning of Primary School Pupils in the Context of Integrated Education: A Case Study
Authors: Jakavonytė-Staškuvienė Daiva , Mereckaitė-Kušleikė Ingrida 
Published: April 2023

AbstractContemporary educational theory and practice increasingly emphasise the importance of integrated education in creating the conditions for success for primary school students. In Lithuania, as part of the 2020–2024 curriculum update and the development of general curricula, integrated education is highlighted as one of the priorities for achieving harmony between pupils’ academic achievements and the development of general competences, as well as the creation of a favourable emotional environment for pupils. This creates a strategic perspective on the content of education. However, there is a lack of research and insights into how such practices can be developed smoothly. For this reason, our research was carried out by targeting one of the Francophone institutes in southern France, which has successfully implemented an integrated education practice that enables learning for every pupil in the primary grades. The study analysed the context, i.e. the concept of the educational institution’s activities, which shows what should be done and how it should be done in order to achieve the quality of integrated education. In addition, the data were obtained through semi-structured interviews with 4 teachers at the Institute with experience in integrated education. Qualitative content analysis was used to inductively search for answers describing the essence of integrated education, the most important processes to reflect on before engaging with pupils, and to deductively identify how certain elements contribute to creating the conditions conducive to integrated education and pupils’ successful learning.
Early post-operative anterior segment parameters modifications induced by PreserFlo MicroShunt in primary open-angle glaucoma
Authors: Gambini Gloria , Carlà Matteo Mario , Giannuzzi Federico , Boselli Francesco , Crincoli Emanuele , Caporossi Tomaso , Baldascino Antonio , De Vico Umberto , Savastano Alfonso , Rizzo Stanislao 
Published: April 2023

Abstract
Purpose
The aim this study is to determine anterior chamber parameters variations induced by PreserFlo MicroShunt implantation, in the early post-operative days.

Methods
This is a prospective observational study on 48 eyes undergoing PreserFlo MicroShunt implantation alone (n = 30) or combined with phacoemulsification (n = 18). Anterior chamber depth (ACD) and volume (ACV), central corneal thickness (CCT) and total corneal astigmatism (TCA) were evaluated pre-operatively, post-operatively at day-1 and at 1 week with the Pentacam tomography.

Results
Intraocular pressure decreased significantly from 20.9 ± 4.0 to 8.0 ± 2.8 mmHg (p < 0.0001) and to 10.8 ± 3.7 mmHg (p = 0.0001) at day-1 and week-1, respectively. TCA varied significantly from baseline (1.5 ± 1.2 D) to both day 1 follow up (2.7 ± 1.9 D, p = 0.0003) and week 1 follow up (2.2 ± 1.6 D, p = 0.02). Nevertheless, only K1 showed a transient flattening at day 1, while K2 value didn’t show any statistical variation in the early post-operative period. CCT value rose significantly at day 1 (547 ± 49 vs. 529 ± 32 µm at baseline, p = 0.04), but then returned toward pre-operative values at week 1 (537 ± 39 µm, p = 0.57). In contrast, ACD values changed insignificantly from 3.3 ± 0.9 to 3.7 ± 1.0 mm at day 1 (p = 0.21), and then stabilized at 3.4 ± 0.9 mm (p = 0.82) at week 1 follow up. ACV changed from 150.0 ± 36.2 to 159.5 ± 42.1 mm3 at day 1 (p = 0.58), and successively to 153.9 ± 37.9 mm3 at week 1 follow up (p = 0.96). The subgroup analysis in eyes undergoing standalone PreserFlo implantation didn’t show significant changes in both ACD and ACV.

Conclusion
PreserFlo implantation minimizes the anterior chamber modifications generated by traditional filtering surgery, inducing low and transient corneal and biometric changes only in the very early postoperative period and insignificant changes to ACD and ACV, label of its safety and minimal invasiveness.
A facile impregnation synthesis of Ni-doped TiO2 nanomaterials for dye-sensitized solar cells
Authors: Rajaramanan Tharmakularasa , Velauthapillai Dhayalan , Ravirajan Punniamoorthy , Senthilnanthanan Meena 
Published: April 2023

AbstractThis study reports a facile impregnation method for synthesizing Ni-doped TiO2nanomaterials using P25-TiO2as a starting material. The as prepared nanomaterials were subjected to structural and optical characterizations and subsequently employed in photovoltaic studies. X-ray diffraction (XRD) and Raman studies confirmed that Ni doping did not alter the anatase and rutile contents of P25-TiO2. Also, the presence of the constituent dopants and their ionic states were confirmed by Energy-Dispersive X-ray (EDX) and X-ray photoelectron (XPS) spectroscopies. Topographic Atomic Force Microscopic (AFM) images illustrated that Ni doping had increased the surface roughness of the TiO2. Optical characterization by UV-Visible spectroscopy revealed that the Ni doping had caused red shift in light absorption due to reduced TiO2bandgap and improved the dye adsorption on TiO2films. Then, the photocurrent–photovoltage property of the fabricated devices was investigated and the optimized 0.10 wt% Ni-doped TiO2photoanode based device exhibited pronounced power conversion efficiency (PCE) of 6.29% under air mass (AM) 1.5 conditions (100 mWcm−2, 1 sun). Improved charge transport properties were also observed by the electrochemical impedance spectroscopic (EIS) study for the device with optimized Ni-doped TiO2compared to the control device.
Problem Gambling Among Adolescents in Uganda: A Cross-sectional Survey Study
Authors: Anyanwu Michael U. , Demetrovics Zsolt , Griffiths Mark D. , Horváth Zsolt , Czakó Andrea , Bajunirwe Francis , Tamwesigire Imelda 
Published: April 2023

AbstractIn recent years, gambling has evolved and grown substantially with new gambling activities and facilities being introduced, making gambling products and opportunities more available than ever before in Uganda. While the growth of gambling industry is considered to have a beneficial impact on the economy, it is increasingly becoming a social and public health issue especially among a minority of young people who experience problem gambling, which can damage personal, family, vocational, and academic pursuits. The present study estimated the prevalence of problem gambling and identified the socio-demographic, school, environmental and health risks of problem gambling among secondary school students in Mbarara Municipality, Uganda. A cross-sectional study was conducted among secondary school students in Mbarara Municipality. A total of 921 students from 12 schools were recruited using cluster sampling. An ordinal logistic regression model was used to explore the relationship between problem gambling and the socio-demographic, academic, environmental and health variables. Of 905 participants, 362 reported having ever gambled (40%), and 160 were classified as problem gamblers (17.7%; 44.2% among those who had ever gambled). Problem gambling was significantly associated with being male, being non-religious, other religion (African traditional religion), having employment (outside of school), distance to nearest gambling venue, parental gambling, peer gambling, substance use, risky sexual behavior, and psychological distress. The present study found a very high prevalence of problem gambling among Ugandan secondary school students. Therefore, there is need to institute public health measures towards raising awareness, prevention and treatment of problem gambling among Ugandan adolescents.
Policy formation for adult migrant language education in England: national neglect and its implications
Authors: Simpson James , Hunter Ann-Marie 
Published: April 2023

AbstractThis article is about current policy in the coordination of opportunities for adult migrants in England to learn English. People who move to a different country experience a need to learn the dominant language of their new environment, to support their settlement. A willingness to learn the language is a marker of social inclusion from a political perspective too: an insistence that migrants have an obligation to learn and use the language is a recurrent trope in political and media discourse. In the UK, language education for adult migrants focuses on the area of education known as ESOL, English for Speakers of Other Languages. Beyond the rhetoric, policy support for migrants’ learning of English across the UK is inconsistent: there is neither a UK-wide nor an England-specific strategy in policy to support access to ESOL. Where policy exists, it is formed at a local level in the absence of national direction. The aim of this paper is to consider how an important area of adult education appears to have little presence in national policy, and what the implications of this are, for practice. To achieve this, we first follow the trajectory of ESOL policy in England, considering why—despite attempts to address its coordination—there remains a lacuna. Second, we ask what the implications are of this policy gap for ESOL coordination in practice. Analysis of current policy and of interviews with key ESOL stakeholders suggests an enduring condition of fragmentation and lack of coordination to the detriment of students.
Pregnant in a Pandemic: Mental Wellbeing and Associated Healthy Behaviors Among Pregnant People in California During COVID-19
Authors: Phipps Jennifer E. , Whipps Mackenzie D. M. , D’Souza Indira , LaSalle Janine M. , Simmons Leigh Ann 
Published: April 2023

Abstract
Introduction
Pregnancy is a time of increased vulnerability to mental health disorders. Additionally, the COVID-19 pandemic has increased the incidence of depression and anxiety. Thus, we aimed to assess mental health and associated healthy behaviors of pregnant people in California during the pandemic in order to contextualize prenatal well-being during the first pandemic of the twenty-first century.

Methods
We conducted an online cross-sectional study of 433 pregnant people from June 6 through July 29, 2020. We explored 3 hypotheses: (1) mental health would be worse during the pandemic than in general pregnant samples to date; (2) first-time pregnant people would have worse mental health; and (3) healthy behaviors would be positively related to mental health.

Results
Many of our participants (22%) reported clinically significant depressive symptoms and 31% reported clinically significant anxiety symptoms. Multiparous pregnant people were more likely to express worries about their own health and wellbeing and the process of childbirth than were primiparous pregnant people. Additionally, as pregnancy advanced, sleep and nutrition worsened, while physical activity increased. Lastly, anxious-depressive symptomology was significantly predictive of participant sleep behaviors, nutrition, and physical activity during the past week.

Discussion
Pregnant people had worse mental health during the pandemic, and this was associated with worse health-promoting behaviors. Given that the COVID-19 pandemic and associated risks are likely to persist due to low vaccination rates and the emergence of variants with high infection rates, care that promotes mental and physical well-being for the pregnant population should be a public health priority.