bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stress experiences of healthcare assistants in family practice at the onset of the COVID-19 pandemic: a mixed methods study
Authors: Schrader Hanna , Ruck Jessica , Borgulya Gábor , Parisi Sandra , Ehlers-Mondorf Jana , Kaduszkiewicz Hanna , Joos Stefanie , Grau Anna , Linde Klaus , Gágyor Ildikó 
Published: September 2023

BackgroundAt the beginning of the pandemic in 2020, healthcare assistants in general practices were confronted with numerous new challenges. The aim of the study was to investigate the stress factors of healthcare assistants in March/April 2020 as well as in the further course of the pandemic in 2020.MethodsFrom August to December 2020, 6,300 randomly selected healthcare assistants in four German states were invited to participate in the study. We performed a mixed methods design using semi-structured telephone interviews and a cross-sectional survey with quantitative and open questions. The feeling of psychological burden was assessed on a 6-point likert-scale. We defined stress factors and categorized them in patient, non-patient and organizational stress factors. The results of the three data sets were compared within a triangulation protocol.ResultsOne thousand two hundred seventy-four surveys were analyzed and 28 interviews with 34 healthcare assistants were conducted. Of the participants, 29.5% reported experiences of a very high or high feeling of psychological burden in March/April 2020. Worries about the patients’ health and an uncertainty around the new disease were among the patient-related stress factors. Non-patient-related stress factors were problems with the compatibility of work and family, and the fear of infecting relatives with COVID-19. Organizational efforts and dissatisfaction with governmental pandemic management were reported as organizational stress factors. Support from the employer and team cohesion were considered as important resources.DiscussionIt is necessary to reduce stress among healthcare assistants by improving their working conditions and to strengthen their resilience to ensure primary healthcare delivery in future health crises.
Retrospective quantification of clinical abdominal DCE-MRI using pharmacokinetics-informed deep learning: a proof-of-concept study
Authors: Wu Chaowei , Wang Nan , Gaddam Srinivas , Wang Lixia , Han Hui , Sung Kyunghyun , Christodoulou Anthony G. , Xie Yibin , Pandol Stephen , Li Debiao 
Published: September 2023

IntroductionDynamic contrast-enhanced (DCE) MRI has important clinical value for early detection, accurate staging, and therapeutic monitoring of cancers. However, conventional multi-phasic abdominal DCE-MRI has limited temporal resolution and provides qualitative or semi-quantitative assessments of tissue vascularity. In this study, the feasibility of retrospectively quantifying multi-phasic abdominal DCE-MRI by using pharmacokinetics-informed deep learning to improve temporal resolution was investigated.MethodForty-five subjects consisting of healthy controls, pancreatic ductal adenocarcinoma (PDAC), and chronic pancreatitis (CP) were imaged with a 2-s temporal-resolution quantitative DCE sequence, from which 30-s temporal-resolution multi-phasic DCE-MRI was synthesized based on clinical protocol. A pharmacokinetics-informed neural network was trained to improve the temporal resolution of the multi-phasic DCE before the quantification of pharmacokinetic parameters. Through ten-fold cross-validation, the agreement between pharmacokinetic parameters estimated from synthesized multi-phasic DCE after deep learning inference was assessed against reference parameters from the corresponding quantitative DCE-MRI images. The ability of the deep learning estimated parameters to differentiate abnormal from normal tissues was assessed as well.ResultsThe pharmacokinetic parameters estimated after deep learning have a high level of agreement with the reference values. In the cross-validation, all three pharmacokinetic parameters (transfer constant Ktrans, fractional extravascular extracellular volume ve, and rate constant kep) achieved intraclass correlation coefficient and R2 between 0.84–0.94, and low coefficients of variation (10.1%, 12.3%, and 5.6%, respectively) relative to the reference values. Significant differences were found between healthy pancreas, PDAC tumor and non-tumor, and CP pancreas.DiscussionRetrospective quantification (RoQ) of clinical multi-phasic DCE-MRI is possible by deep learning. This technique has the potential to derive quantitative pharmacokinetic parameters from clinical multi-phasic DCE data for a more objective and precise assessment of cancer.
Improved Quality of Life Among Chronic Pancreatitis Patients Undergoing Total Pancreatectomy With Islet Autotransplantation—Single Center Experience With Large Cohort of Patients
Authors: Coluzzi Mariagrazia , Takita Morihito , Saracino Giovanna , Rub Hakim Mohammed Abdul , Darden Carly M. , Testa Giuliano , Beecherl Ernest , Onaca Nicholas , Naziruddin Bashoo 
Published: September 2023

Total pancreatectomy with islet autotransplantation (TPIAT) is the treatment of choice to preserve pancreatic endocrine function, alleviate pain, and improve quality of life (QoL) when other strategies are ineffective for chronic pancreatitis (CP) patients. This study utilized pancreatic disease-specific surveys developed by the European Organisation for Research and Treatment of Cancer (EORTC) to conduct a comprehensive, single-center examination of a large cohort of patients to gain understanding of QoL post-TPIAT. Two validated QoL surveys of the EORTC—QLQ-C30 and QLQ-PAN26—were administered in a prospective cohort of CP patients during pre-and post-operative scheduled visits. A total of 116 patients responded to the preoperative survey and were included in this study. The global health scale of QLQ-C30 was significantly improved after TPIAT when compared to baseline with delta scores of 24.26, 20.54, and 26.7 at 1, 2, and 3 years post-TPIAT (p&lt; 0.001). The EORTC-PAN26 revealed significant improvements in symptom scales for pancreatic pain, bloating, digestive symptoms, taste, indigestion, weight loss, body image, and future worries. The comprehensive surveys in such a large cohort expands the QoL criterion in CP patients and indicates significant improvement in QoL post-TPIAT, further validating TPIAT as a treatment option for refractory CP.
Alleviation of Stripe Rust Disease in Wheat Seedlings Using Three Different Species of Trichoderma spp.
Authors: Mourad Amira M. I. , Börner Andreas , Esmail Samar M. 
Published: September 2023

Wheat stripe rust (WSR) caused by Puccinia striiformis F. tritici Erikss. (Pst) is one of the serious diseases that affect wheat planting areas around the world. Many efforts have been made to control such a serious disease including using fungicides and breeding highly resistant genotypes. However, due to Pst’s ability to produce new races that overcome these fungicides and break the resistance in the highly resistant genotypes, looking for other effective ways to restrict this disease is urgently required. One of the highly effective ways of controlling crop diseases is using biological control. In this study, the efficiency of three different Trichoderma species (Trichoderma asperellum T34, Trichoderma harzianum (TH), and Trichoderma verdinium (TV)) was tested in a set of 34 wheat genotypes at the seedling stage. The evaluation was conducted in two experiments with two different temperature regimes. In each experiment, four treatments were applied, namely, control, T34, TV, and TH. High genetic variation was found among all genotypes in each experiment and under each Trichoderma treatment. Notably, the symptoms of WSR were affected by temperature under all treatments except T34, which had a stable performance in the two experiments. The 34 studied genotypes were highly diverse, related to ten different countries, and consisted of durum and bread wheat. Out of the three studied Trichoderma species, T34 was able to improve WSR resistance in all the studied genotypes suggesting its effectiveness in inducing the resistance and producing a priming response in different wheat genetic backgrounds. The results of this study provided very useful information on the effectiveness of Trichoderma spp. in controlling WSR.
PROCESSO DE IMPLEMENTAÇÃO DO PRONTUÁRIO ELETRÔNICO NA ATENÇÃO BÁSICA: FACES E INTERFACES NO CUIDADO EM SAÚDE DA FAMÍLIA
Authors: Salustino dos Santos Maria Carolina , Diniz Souza Élida de Fátima , Dos Santos Gomes Anne Carolinne Marie , Maciel de Melo Anna Laura , De Oliveira e Silva Merlayne Pâmela , Gouveia de Sousa Vinícius André , De Almeida Cardoso Liliane , Cecchetti Vaz Elenice Maria 
Published: September 2023

Objetivo: Descrever o processo de implementação do Prontuário Eletrônico na atenção básica à luz da literatura. Método: Revisão integrativa da literatura, realizada nas bases/bibliotecas de dados selecionadas para a pesquisa foram: Literatura Latino-Americana e do Caribe em Ciências da Saúde – LILACS, Medical Literature Analysis and Retrievel System Online – MEDLINE, Google acadêmico e Scientific Electronic Library Online – SciELO, entre os meses de novembro e dezembro do ano de 2022. A pesquisa reuniu 10 artigos sobre o tema, que foram organizados em dois quadros. Resultados: Predominaram-se artigos do ano de 2021, com abordagem qualitativa, e nível de evidência VI. A partir de uma análise descritiva, foram elencadas os seguintes termos-definidores: Gestão do Cuidado; Integração; Relações humanas; Desafios; Capacitação dos profissionais; Colaboração e Contribuição do PEC. Conclusão: Conclui-se que a implementação do PEC ainda é um desafio, e que quando ela ocorre, traz inúmeros benefícios para a Saúde da Família.
Optical Switching Data Center Networks: Understanding Techniques and Challenges
Authors: Zhao Yisong , Xue Xuwei , Ren Xiongfei , Li Wenzhe , Guo Yuanzhi , Yang Changsheng , Dang Daohang , Zhang Shicheng , Guo Bingli , Huang Shanguo 
Published: September 2023

Relying on the flexible-access interconnects to the scalable storage and compute resources, data centers deliver critical communications connectivity among numerous servers to support the housed applications and services. To provide the high-speeds and long-distance communications, the data centers have turned to fiber interconnections. With the stringently increased traffic volume, the data centers are then expected to further deploy the optical switches into the systems infrastructure to implement the full optical switching. This paper first summarizes the topologies and traffic characteristics in data centers and analyzes the reasons and importance of moving to optical switching. Recent techniques related to the optical switching, and main challenges limiting the practical deployments of optical switches in data centers are also summarized and reported.
Economic security of the CIS Member States at the present and future
Authors: Muntiyan V. 
Published: September 2023

In these adverse circumstances the role and importance of ensuring economic security is growing significantly as the main subsystem of national and collective security CIS. The article presents the comparative dynamics of the GDP of the CIS countries, the world and developing countries. The characteristic of the main indicators of the economic security of the CIS member states for a given period of time is given.
The analysis of the integrated economic security assessment of the CIS states shows that the system of economic security of the states does not yet correspond to the strategic goals and objectives for their achievement. Conclusions are drawn and recommendations are given to improve the level of economic security of the CIS countries.
The vector of social development or the vector of social degradation. Project to create cybernetic transhumanity in the New World Order
Authors: Matveev Vladimir 
Published: September 2023

In accordance with the requirements of the National Security Strategy of the Russian Federation to save the people of Russia and develop human potential, an analysis of the management of the Global historical process was carried out and criteria for assessing socio-economic development/degradation in each historical era were formulated.
In order to assess the quality of the person himself and the process of his improvement, the formation of the basis of his behavior, the concept of the structure of the psyche is formulated and a model of the process of personality development is proposed. A method for assessing the quality of social management is given both from the point of view of consistency within civilizational management, and from the standpoint of management stability in relation to the global evolutionary process of the Earth's biosphere.
The intention of the globalists to transform the person himself and the algorithms of his social behavior in the process of establishing the New World Order is analyzed. The goals and objectives of the New Age movement are analyzed as a system of compilation of many religious and secular cults, programs of their actions.
As part of the hybrid war, the idea of globalists is presented on the ephemeral merging of biology and technology, the transformation of the “body/mind system” with the digital infrastructure of the world economy. The technology of using brain-computers to change human culture, creating wearable devices for hacking brain waves is demonstrated. The introduced technologies for the transition from human potential to social potential, the globalization of transhumanism of neurofeedback are illustrated.
The convergence of some forecasts of globalists for today and their forecasts for the future is presented. Some recommendations are formulated to ensure the national security of the Russian Federation on the basis of the state policy for the preservation and strengthening of traditional Russian spiritual and moral values.
Láminas de riego y su influencia en el rendimiento de arroz (Oriza sativa L.) la variedad Fedearroz-67 en el Valle Cálido del Magdalena
Authors: Montenegro-Ramos Omar , Jaramillo-Bonilla Sair , Abaunza-González Carlos 
Published: September 2023

l perfil cultural, distribución de poros por tamaño, textura y análisis de caracterización química. Los sistemas modales producto del uso y manejo del suelo identificados para la zona fueron: sistema bosque secundario, sistema pradera mejorada, sistema arroz barbacho, sistema arroz con pastoreo de soca, sistema de lotes abandonados, sistema de arroz en monocultivo por 10 años y sistema de arroz em monocultivo por 20 años. Con las variables evaluadas, se encontró una mayor degradación de suelos en los sistemas de arroz en monocultivo por 10 y 20 años y lotes abandonados. Al evaluar los resultados de la caracterización física se encontró que los valores más contrastantes y que sirvieron para diferenciar claramente los sistemasmencionados, determinando diferentes niveles de degradación física fueron: infiltración, conductividad hidráulica, densidad aparente, porosidad total, distribución de poros por tamaño y resistencia a la penetració El cultivo del arroz, tradicionalmente, permanece la mayor parte de su ciclo biológico con inundación y manifiesta una elevada adaptabilidad a dichas condiciones, por lo tanto, para su producción se utiliza una gran cantidad de agua de riego. La investigación se realizó con el objetivo identificar volúmenes de agua óptimos a partir de cuatro volúmenes de riego (8.000, 16.000, 24.000 y 32.0000 m3/ha/ciclo) y analizar el comportamiento de la variedad Fedearroz-67. La aplicación de 16.000 m3/ha/ciclo presentó un rendimiento de 8.743 kg/ha, siendo estadísticamente igual a los rendimientos obtenidos con la aplicación de volúmenes superiores de 24.000 y 32.000 m3/ha, pero superando al tratamiento de 8.000 m3/ha /ciclo en el 40%. Los mayores porcentajes de vaneamiento, se presentaron con el nivel más bajo de aplicación de riego. El macollamiento y el número de panículas alcanzaron los mayores valores con la aplicación de 32.000 m3/ha/ciclo. El tratamiento con un volumen de aplicación de 16.000 m3/ha/ciclo permite tener los mayores márgenes de rentabilidad y un ahorro de agua de más del 50% con respecto a los volúmenes comúnmente utilizados por los agricultores de la zona el cual es de 30.000 a w35.000m3/ha/ciclo. Así, el agua ahorrada pudiera incrementar el área bajo riego en un 25 % para el cultivo del arroz, o en 6.300 ha en cultivos de secano manejado con mojes.
Achromobacter Xylosoxidans/Denitrificans İnfeksiyonları: Literatürün Gözden Geçirilmesi
Authors: DİNDAR DEMİRAY Emine Kübra , ALKAN Sevil 
Published: September 2023

Achromobacter cinsi gram negatif bakterilere bağlı gelişen infeksiyonlar insanlarda oldukça nadir olmakla birlikte, literatürde ülkemizden de çeşitli vaka bildirimleri mevcuttur. Bu çalışmada Achromobacter denitrificans infeksiyonlarını ve klinik önemini gözden geçirmeyi amaçladık.
Achromobacter spp. altta yatan hastalıkları olan, çeşitli invaziv girişimler uygulanan, uzun süre hastanede yatan hastalarda gelişen çeşitli nozokomiyal infeksiyonların (sepsis, yara enfeksiyonu, gibi) etkenleri arasındadır. Achromobacter spp. gerek toplum ve gerekse de sağlık bakımı ilişkili nadir bir infeksiyon etkenidir.
Sonuç olarak uygun tedavi seçeneklerini belirlemek için antibiyotik duyarlılık paterninin mutlaka çalışılması gerektiği unutulmamalıdır.
DiskMINT: A Tool to Estimate Disk Masses with CO Isotopologues
Authors: Deng Dingshan , Ruaud Maxime , Gorti Uma , Pascucci Ilaria 
Published: September 2023

Abstract
CO is one of the most abundant molecules in protoplanetary disks, and optically thin emission from its isotopologues has been detected in many of them. However, several past works have argued that reproducing the relatively low emission of CO isotopologues requires a very low disk mass or significant CO depletion. Here, we present a Python code, DiskMINT, which includes gas density and temperature structures that are both consistent with the thermal pressure gradient, isotope-selective chemistry, and conversion of CO into CO2 ice on grain surfaces. The code generates a self-consistent disk structure, where the gas disk distribution is obtained from a spectral energy distribution (SED)–derived dust disk structure with multiple grain sizes. We use DiskMINT to study the disk of RU Lup, a high-accreting star whose disk was previously inferred to have a gas mass of only ∼1.5 × 10−3
M
⊙ and gas-to-dust mass ratio of ∼4. Our best-fit model to the long-wavelength continuum emission can explain the total C18O luminosity as well as the C18O velocity and radial intensity profiles, and it obtains a gas mass of ∼1.2 × 10−2
M
⊙, an order of magnitude higher than previous results. A disk model with parametric Gaussian vertical distribution that better matches the IR SED can also explain the observables above with a similarly high gas mass ∼2.1 × 10−2
M
⊙. We confirm the conclusions of Ruaud et al. that optically thin C18O rotational lines provide reasonable estimates of the disk mass and can therefore be used as gas disk tracers.
The Discrepancy between Observed and Predicted Heliospheric Energetic Neutral Atoms below Solar Wind Energy
Authors: Galli André , Baliukin Igor I. , Kornbleuth Marc , Opher Merav , Fuselier Stephen A. , Sokół Justyna M. , Dialynas Konstantinos , Dayeh Maher A. , Izmodenov Vladislav V. , Richardson John D. 
Published: September 2023

Abstract
Measuring energetic neutral atoms (ENAs) allows for the remote observation of ion populations from the frontiers of our heliosphere. In this study, we compare the ENAs observed with the IBEX-Lo instrument onboard the Interstellar Boundary Explorer with ENA predictions from two heliosphere models. In contrast to previous studies, this paper presents model-data comparisons for the energy range 50 eV–2 keV over one full solar cycle not only in the upwind direction (Voyager 1 and Voyager 2 sky directions), but also for the north pole, south pole, port tail lobe, and downwind directions. The two heliosphere models produce the same basic result: there is a large gap (1 to 2 orders of magnitude in ENA intensity at 100 eV) between ENA data and model predictions between 100 and 500 eV for all sky directions. The reason for this gap is not understood yet. While some explanations are plausible and will be investigated in future studies, other explanations are excluded.
The FRB 20190520B Sight Line Intersects Foreground Galaxy Clusters
Authors: Lee Khee-Gan , Khrykin Ilya S. , Simha Sunil , Ata Metin , Huang Yuxin , Prochaska J. Xavier , Tejos Nicolas , Cooke Jeff , Nagamine Kentaro , Zhang Jielai 
Published: September 2023

Abstract
The repeating fast radio burst FRB 20190520B is an anomaly of the FRB population thanks to its high dispersion measure (DM = 1205 pc cm−3) despite its low redshift of z
frb = 0.241. This excess has been attributed to a large host contribution of DMhost ≈ 900 pc cm−3, far larger than any other known FRB. In this paper, we describe spectroscopic observations of the FRB 20190520B field obtained as part of the FLIMFLAM survey, which yielded 701 galaxy redshifts in the field. We find multiple foreground galaxy groups and clusters, for which we then estimated halo masses by comparing their richness with numerical simulations. We discover two separate M
halo > 1014
M
⊙ galaxy clusters at z = 0.1867 and 0.2170 that are directly intersected by the FRB sight line within their characteristic halo radius r
200. Subtracting off their estimated DM contributions, as well that of the diffuse intergalactic medium, we estimate a host contribution of

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(observed frame), depending on whether we assume that the halo gas extends to r
200 or 2 × r
200. This significantly smaller DMhost—no longer the largest known value—is now consistent with Hα emission measures of the host galaxy without invoking unusually high gas temperatures. Combined with the observed FRB scattering timescale, we estimate the turbulent fluctuation and geometric amplification factor of the scattering layer to be

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, suggesting that most of the gas is close to the FRB host. This result illustrates the importance of incorporating foreground data for FRB analyses both for understanding the nature of FRBs and to realize their potential as a cosmological probe.
Formation and Evolution of Transient Jets and Their Cavities in Black Hole X-Ray Binaries
Authors: Sikora Marek , Zdziarski Andrzej A. 
Published: September 2023

Abstract
We propose a model explaining the origin of transient/episodic jets in black hole X-ray binaries, in which they are caused by transitions from a collimated, strongly magnetized jet to a wide, uncollimated outflow. The change occurs when the accretion flow leaves the magnetically choked state due to an increase of the accretion rate for a weakly varying magnetic flux. The formed powerful jet then detaches from its base, and propagates as a discrete ejection. The uncollimated outflow then produces a relativistic plasma that fills the surroundings of the black hole, contributing to the formation of a low-density cavity. While the pressure in the cavity is in equilibrium with the surrounding interstellar medium (ISM), its inertia is orders of magnitude lower than that of the ISM. This implies that the plasma cannot efficiently decelerate the ejecta, explaining most of the observations. The modest deceleration within the cavities observed in some cases can then be due to the presence of clouds and/or filaments, forming a wide transition zone between the cavity and the ISM.