bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigating Air Pollutant Trends Based on Temporal Air Quality Indexes in Karaj, Iran, during 2012 − 2018
Authors: Noorisepehr Mohammad , Vosoughi Mehdi , Chavoshani Afsane , Eskandari Zahra 
Published: July 2023

Aim:
Due to the importance of the relationship between air pollutants and the incidence of many diseases in polluted cities, in this study, we collected the data related to yearly, seasonally, monthly, daily, and hourly concentrations of particulate matter (PM) 2.5, PM10, sulfur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO), and ozone (O3) recorded at four monitoring stations across Karaj city, Iran, to investigate the air pollutant trends based on air quality indexes (AQIs) in the city during 2012–2018.

Materials and Methods:
The correlations between PMs and gaseous pollutants were analyzed using the Pearson correlation coefficient. The concentrations of air pollutants indexes including O3, NO2, SO2, CO, PM10, and PM2.5 were recorded in four air pollution monitoring stations in Karaj obtained from the monitoring system of the environment department. Then, the data were analyzed using SPSS and Graph pad softwares.

Results:
The findings showed that in 20%–40% and 1%–5% of days during 2012–2018, higher concentrations of PM2.5 and PM10 were experienced than the national standard (NS) concentration, respectively. Furthermore, during this time, 0.3%–0.9% of days indicated the higher concentrations of CO and SO2 than the NS, respectively. Although the daily concentration of NO2 was lower than NS, 0.5%–5% of days were exposed to the higher concentration of O3 than NS. SO2 concentration showed a negative and positive correlation with PM10 (r = −0.69, P = 0.013) and O3(r = 0.58, P = 0.03), respectively.

Conclusion:
These results indicated that Karaj AQI was moderate and the most problem with air quality in Karaj city was attributed to the PM2.5 concentrations. To reduce health disorders related to this pollutant, it is necessary to control PM2.5 sources and sensitive groups should reduce outdoor activities.
Transtorno do Espectro do Autismo (TEA): breve história para uma longa discussão.
Authors: Souza Fernandes Murilo Henrique de , Costa e Silca Ana Lucia 
Published: July 2023

O Transtorno do Espectro Autista (TEA) é uma condição geral que se caracteriza por baixa interatividade social, pouca habilidade comunicativa (tanto verbal quanto não verbal), comportamentos repetitivos e estereotipados, bem como um repertório mais restrito de interesses nas atividades propostas. O objetivo do presente trabalho foi fazer uma busca teórica inicial, destacando as informações que se tem sobre o tema a fim de instigar discussões e reflexões sobre o autismo, a partir das informações e debates presentes. A metodologia utilizada foi a revisão bibliográfica, com recorte dos artigos e dados entre os anos de 2012 e 2021, nas bases de dados como Scielo, BVS e CAPES, a fim de responder às seguintes inquietações: quais as causas do autismo; qual o tratamento específico para pessoas com TEA e seus familiares; se autismo tem cura e como investir em políticas públicas para inclusão e equidade das pessoas com TEA. Os resultados apontam para a continuidade de estudos e discussões sobre o tema, com maior inclusão e equidade das pessoas com autismo e suas famílias e mais pesquisas sobre o tema, dentro do contexto brasileiro, uma vez que algumas questões ainda continuam sem respostas ou com insuficiência de dados que permitam o avanço na discussão sobre o tema.
The mutational landscape of genetic cholestatic diseases in Pakistani children
Authors: Cheema Huma Arshad , Waheed Nadia , Anjum Saeed  , Anjum Muhammad Nadeem , Fayyaz Zafar , Ijaz Sadaqat 
Published: July 2023

Objective: To report the mutational landscape of a clinically diagnosed cohort of paediatric patients with cholestasis liver diseases.
Method: The retrospective study was conducted at the University of Child Health Sciences, The Children Hospital, Lahore, Pakistan, from December 10, 2021, to March 31, 2022, and comprised data collected from the Paediatric Gastroenterology and Hepatology unit on demographics, clinical and laboratory findings related to children of either gender aged <12 years and diagnosed with cholestatic liver disease from July 2018 to June 2021. The diagnosis was based on clinical and biochemical findings, with no evidence of biliary atresia and metabolic liver disease. Molecular characterisation was done through whole exome sequencing.
Results: Of the 171 children evaluated, 92(53.8%) were diagnosed with genetic cholestatic disorders. There were 52(56%) boys and 41(44%) girls. The median age at presentation was 19.5 months (interquartile range: 51 months). Consanguinity was found in 82(88.1%) cases, and positive family history with one or more affected siblings was noted in 60(64.5%). Exome sequencing identified pathogenic mutations in 13 genes underlying the hereditary cholestasis; ATP8B1, ABCB11, ABCB4, TJP2, NR1H4, DCDC2, ACOX2, AKR1D1, HSD3B7, ABCC2, USP53, SLC10A1, and SLC51A. Of the 70 variants identified, 50(71.4%) were novel variants. The ABCB11-related hereditary cholestasis was the most frequent 27(29%), followed by ABCB4 (26(27.9%). Homozygosity was frequently seen in all except 8(8.6%) children, who had compound heterozygous pathogenic variants. There was no evidence of phenotypic expression in the carrier parents despite the severe nature of the respective mutations identified in the patients.
Conclusions: Genetic heterogeneity of paediatric intrahepatic cholestasis showed recurrent and novel mutations.
Key Words: Cholestasis, Progressive familial intrahepatic cholestasis, Neonatal sclerosing cholangitis, Genetic mutation, USP53, Bile acid synthetic defects, CLD.
Pengembangan Instrumen Penilaian Pemahaman Konsep Business Model Canvas pada Mata Kuliah Kewirausahaan
Authors: Machsunah Yayuk Chayatun , Nurdiana Ratna , Sutarum Sutarum 
Published: July 2023

Business Model Canvas (BMC) adalah business model yang harus dikuasai mahasiswa dalam mata kuliah kewirausahaan sebagai bekal awal terjun dalam dunia wirausaha. Penelitian ini akan menghasilkan instrumen penilaian guna mengukur pemahaman konseptual mahasiswa dalam materi BMC yang terdiri dari 9 aspek penilaian yaitu Customers Segment, Value proposition, Customer Relationship, Channel, Revenue Stream, Key Resource, Key aktivities, Key Partnership, dan Cost Structure. Instrumen penilaian dikembangkan menggunakan model ADDIE (Analysis, Design, Development, Implementation and Evaluations). Validitas konten dilakukan oleh validator ahli dan diperoleh nilai sebesar 93,75% yang artinya sangat valid. Sedangkan hasil analisis statistik diperoleh nilai korelasi lebih dari 0,30. Ini berarti seluruh aspek penilaian tersebut dinyatakan valid. Nilai reliabilitas Cronbach’s Alpha diperoleh sebesar 0,886 artinya instrument memiliki kemampuan sangat kuat dalam alat ukur penelitian, sehingga dapat disimpulkan bahwa instrumen penilaian pemahaman konseptual BMC valid dan layak untuk digunakan pada materi business model mata kuliah kewirausahaan
The Study of Higher Education in the Regions of Kazakhstan: Analysis of Tools and Indicators
Authors: Nurgaliyeva Kuralay , Nygymbetov Galym 
Published: July 2023

This study aimed to analyse the state of higher education in the regions of Kazakhstan based on an integrated approach according to use of statistical methods and aggregation of empirical data. In this study, the focus is on assessing the level of development of higher education institutions in Kazakhstan based on the selected three groups of variables: enrollment in higher education institutions; subjects and objects of higher professional education (number of teaching staff, number of students, number of universities); provision of services (budget, population, enterprises). The research design was divided into three stages: data collection, analysis and recommendations. The data sample from 2010 to 2021 was taken from the annual statistical yearbooks of the Republic of Kazakhstan. In this study based on a comprehensive review of the above variables, it is proposed to conduct an analysis at the following three stages: data collection, definitions of the initial data and evaluation of the time period; sampling of initial data, analysis of collected data and interpretation; description of the results obtained; conclusions and recommendations. The practical results of the study and conclusions can be used by government agencies in the analysis and forecasting of the development of the education system in the region. The data obtained showed that there are differences in the availability of higher education in different regions of Kazakhstan. High rates in the cities of Astana and Almaty may be associated with their status as the capital and the largest city, respectively.
A ENTREGA VOLUNTÁRIA DE CRIANÇAS RECÉM-NASCIDAS PARA ADOÇÃO: ANÁLISE BIBLIOGRÁFICA SOBRE O ACOMPANHAMENTO REALIZADO ATÉ O PARTO
Authors: Trindade Mendonça Iara 
Published: July 2023

Podemos dizer que não são raras as vezes em que nos deparamos com notícias na mídia sobre mães que abandonam seus filhos pós-parto em locais como: lotes, lixões, terrenos baldios, esgoto, entre outras situações deploráveis. Diante dessa problemática, surge todo um estudo e questão de saúde pública, tornando o processo de entrega voluntária menos doloroso e mais humano, dando amparo e suporte para as mães e pais que, apesar do não interesse em permanecer com seus filhos, desejam lhes dar uma vida mais digna por meio da entrega voluntária para a adoção, garantindo aos genitores a possibilidade de manter suas identidades resguardadas sem nenhum tipo de responsabilização civil ou criminal. Objetivo: Descrever como o processo de entrega voluntária é segura e acolhedora. Métodos: O presente artigo tem sua metodologia pautada em pesquisas bibliográficas, análise da legislação relativa ao tema, além de pesquisas de artigos da área jurisdição e projetos de lei referentes ao tema. Resultados: Os artigos inicialmente encontrados nas bases de dados, após a inserção das palavras-chave, totalizaram 100, restando 5 artigos científicos originais que cumpriram as exigências e normas da revisão interativa e que possuíam relação direta com a temática abordada. Considerações finais: A legislação brasileira mudou bastante ao que se refere à adoção, nos últimos tempos foram criados inúmeros mecanismos que possibilitam a garantia dos direitos fundamentais de crianças e adolescentes em situação de abandono familiar.
United Arab Emirates (UAE): A scientometric assessment of Covid-19 publications
Authors: Gupta B. M. , Dhawan S.M. , Kappi Mallikarjun 
Published: July 2023

Objective. The United Arab Emirates continues to undertake and sustain its research pursuits in Covid-19 as a matter of strategy, considering that the country is facing unique challenges in this area of research. The paper seeks to analyze UAE publications on Covid-19 research and describe its research trends.
Methodology. A literature search on UAE publications on Covid-19 was conducted using the Scopus database, limiting the search period for the study to December 1, 2019 - April 7, 2023. Data were retrieved and downloaded for analysis using Microsoft Excel and Scopus Citation Overview tools. VOSviewer software was used to provide creative visualization of the relationships across researchers, institutions, and journals that reported UAE publications.
Results: 48,1461 publications were published on Covid-19 from December 2019 till April 7, 2023. Of these, the UAE contributed 3402 publications, constituting 0.71% share of global output and registered 14.63 average citations per article (CPP). The 732 (21.52%) UAE papers had received external funding support, and another 2493 (73.28%) papers appeared through international collaboration with countries such as the U.K (n=556), USA (n=553), India (n=448), and Saudi Arabia (n=399). The leading UAE participating organizations in Covid-19 research include the University of Sharjah (n=619), United Arab Emirates University (n=520), and Zayed University (n=239). The organizations which made the most citation impact in terms of CPP and RCI include American University in the Emirates (40.54 and 3.34), Mohammed Bin Rashid University of Medical & Health Sciences (34.4 and 2.83), and Al Jalila Children’s Specialty Hospital (31.88 and 2.62). The leading UAE participating authors in Covid-19 research include R. Halwani (n=83), Z. Umar (n=38), and Q. Hamid (n=37). The authors who made the most citation impact in terms of CPP and RCI include R. Halwani (52.61 and 4.33), H.Q. Al Shamsi (30.24 and 2.49) and A.S. Al Dhaheri (28.81 and 2.37). The most utilized channels of research communication in Covid-19 research include PLOS One (n=73), International Journal of Environmental Research & Public Health (n=46), and Scientific Reports (n=36). The journals which received the most citations for UAE papers on Covid-19 research include the International Journal of Infectious Diseases (30.56 CPP), IEEE Access (20.49 CPP), and Frontiers in Psychiatry (17.40 CPP).
Conclusion: The study presents the current status of research and the publication trends in Covid-19 in the UAE, particularly its most used sources for research publication, most productive and most cited organizations and authors, and its most sought-after topics in Covid-19 research. Strengthening research collaboration between UAE and the Middle East countries and with the developed world countries will further help UAE improve the quality and quantity of its research on Covid-19 and help implement its Covid-19 policies in the region.
Abrogation of Article 370: The Symbol of National Integrity
Authors: Ahmad Irshad , Parihar Dr. Seema 
Published: July 2023

A few specific privileges provided to citizens of the Indian state of Jammu and Kashmir were recently abolished by the Indian government. Under Articles 370 and 35A of the Constitution, these rights were provisionally conferred. The Indian government placed some limitations on travel and communication in the Kashmir valley because it anticipates that this step may spark violent protests in the state. Pakistan has spearheaded a defamation campaign against India even though these prohibitions have increasingly been loosened. Over this action, it has even threatened a nuclear exchange. The prime minister of India Mr Narendra Modi said that more than 70,000 lives have been lost over the past thirty years as a result of the particular privileges that the people of Jammu and Kashmir have, which has led to a sense of difference that has been exploited by forces opposed to India’s unity. The neighbourhood was not getting any closer to peace by maintaining the current quo. Hopefully, the elimination of these articles will result in a stronger sense of national integration. Therefore in view of the above statements this dissertation paper is being prepared to study and spread the truth to the all citizens of India that abrogation of article has ended all kinds of privileges and special treatments and has paved the way to the national integration of India
Challenges and Prospects for Organic Farming: A Case Study from India
Authors: Kaur Harmandeep 
Published: July 2023

Several past studies have considered organic farming as it serves as a responsive sustainable approach to the rural development. This study emphasises and focuses on the opportunities and constraints in organic farming in context of India. There are several cost and marketing related problems specific to organic food. This study identify the following areas to addresss these problems in the country: develop a regional programme to address specific regional problems, take into account the unique conditions prevailing in the region; provide financial assistance for the effective implementation of organic projects and programmes, access to advanced technology, effective information sharing platforms. The organic movement’s capacity for adaptation and learning from past experiences will determine if organic farming is able to fully realise its capacity for fostering resilience( Milestad and Darnhofer, 2003).
Changing Pattern of World Trade and Role of Global Supply Chains: Evidences from Recent Literature
Authors: Singh Kulwinder , Kaur Simran , Shalu Kumari 
Published: July 2023

Recent developments in the world economy have substantially increased interdependence among nations, due to which no nation can isolate itself completely from the rest of the world. Internationalization of production has resulted to mutual exchange of goods, services, technologies, people and investment, generally called as supply-chain trade. These processes have dramatically influence structure of production networks in global economy. Traditional domestic production networks have been replaced by much modernized global ones. The trade that is taking place through international networks is associated with momentous of global economic changes. These global supply networks have several economic and non economic effects particularly on the business organization involved and generally on the economies/nations as a whole. Trading pattern of world economy has also experiencing changes under the influence on these supply chains. This paper highlights the role of recent global supply chains in changing pattern of world trade. Evidences from literature reveal that recent global supply chains have had a significant effect on pattern of world trade as Newly Emerging Economies (EMEs) are emerging as manufacturing trading partners which was not even dreamt about few years back during 1970s and 1980s. Role of supply chain to make these changes incidental is multidimensional and immense. Paper also highlights role of transnational corporations (TNCs) in coordinating global trade through creation of global supply chains and importance of these chains as instrument of trade policies for firms in developing nations.
The role of negative affects as mediators
in the relationship between stress and mental health in Ecuadorian adolescents
Authors: Moreta-Herrera Rodrigo , Zumba-Tello Doris , de Frutos-Lucas Jaisalmer , Llerena-Freire Stefanía , Salinas-Palma Alexandra , Trucharte-Martínez Almudena 
Published: July 2023

BackgroundStress and negative emotions have adverse consequences for the mental health of adolescents, an area that deserves further examination. These attributes are associated with each other and regularly interact in different ways. The way they exert an influence can be both direct and indirect, so the general objective is to elucidate the potential mediating effect of negative affects in the relationship between stress and mental health in Ecuadorian adolescents.Participants and procedureAn explanatory and mediation design based on structural equation modeling (SEM) was applied with 1154 high school students from Ecuador (67.7% women) aged 14 to 19 years (M = 15.69).ResultsIn our sample, the presence of stress and negative affect is moderate, while that of mental health problems is low. Accord-ing to our final model, these variables covary with and influence each other in the following way: stress (X) has a direct effect on mental health (Y) and also an indirect effect mediated by negative affect (M). The structural regression model pro-posed explains 63% of the variance in mental health.ConclusionsStress exerts a relevant impact on mental health, both through direct and indirect pathways. The indirect pathway, mediat-ed by negative affect, opens the door to novel interventional strategies to foster mental health.
Fear of COVID-19 and future anxiety among Polish university students during a pandemic
Authors: Guszkowska Monika , Bodasińska Anna 
Published: July 2023

BackgroundThe pandemic poses a threat to human health and life, and anxiety is the most common psychological problem occurring during the COVID-19 pandemic. The aim of the study was to establish the differences in the fear of COVID-19 infection and the future anxiety experienced by students during the pandemic by gender, field of study, place of study and paid em-ployment, and their relationships to psychological well-being.Participants and procedureThe study involved 1294 university students aged 18-30. The Future Anxiety Scale and short version of the Psychological General Well-Being Index were used. In addition, students stated whether they were concerned about the possibility of con-tracting the coronavirus and falling ill with COVID-19.ResultsOne-third of respondents stated that they felt fear of contracting the coronavirus. Women experienced a significantly stronger fear of COVID-19 and future anxiety than men. The observed interaction effects show that female students of medical faculties experienced a higher fear of COVID-19 than women studying fields of study related to physical activity and working students experienced a slightly higher future anxiety. A positive, but weak correlation between fear of COVID-19 and future anxiety was found. Psychological well-being correlated poorly with fear of COVID-19 and moderately with future anxiety.ConclusionsBecause future anxiety was stronger in women, medical students, some master’s students and working people, preventive measures should be taken to prevent excessive anxiety and to promote mental health in these groups.
Excessive brain atrophy in patients with severe aortic stenosis
Authors: Chrostowski Jakub , Majos Marcin , Walczak Andrzej , Majos Agata 
Published: July 2023

PurposeTo assess the prevalence of the neuroradiological indices of brain atrophy in patients with severe aortic valve stenosis (AS) in magnetic resonance imaging (MRI) with particular emphasis on the assessment of atrophy areas typical of cerebral small vessel disease (CSVD).Material and methodsThe group of 34 patients (age 60-90 years, 17 women and 17 men) with severe AS and 50 healthy controls (age 61-85 years, 29 women and 21 men) underwent MRI brain examinations, which were analysed for the neuroradiological indices of brain atrophy.ResultsA slight but statistically significant age difference was found between the study and control groups – about 3 years on average (<i>p</i> = 0.040). Differences between total brain volumes in both the groups did not show statistical significance. In a comparative analysis of the main brain compartments, a statistically significant difference was found only in the volumetry of cerebral hemispheres for both the groups: mean volume of cerebral hemispheres in patients with severe AS was 884.46 cm³, while it was 17 cm³ bigger in the volunteer group, reaching 901.80 cm³ on average (<i>p</i> = 0.043). Comparison of the volumetry of the other major and minor regions and structures according to the clinical and anatomical division revealed statistically non-significant differences. No statistically significant relationships were observed concerning structures correlated with CSVD.ConclusionsNeuroradiological indices of the brain atrophy do not provide an unequivocal distinction in patients with severe AS. Most observations imply that brain atrophy in patients with severe AS is primarily a consequence of physiological ageing of the brain.