bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long‐term outcome of liver transplantation for autoimmune hepatitis: A French nationwide study over 30 years
Authors: Chouik Yasmina , Chazouillères Olivier , Francoz Claire , De Martin Eleonora , Guillaud Olivier , Abergel Armand , Altieri Mario , Barbier Louise , Besch Camille , Conti Filomena , Corpechot Christophe , Dharancy Sébastien , Durand François , Duvoux Christophe , Gugenheim Jean , Hardwigsen Jean , Hilleret Marie‐Noëlle , Houssel‐Debry Pauline , Kamar Nassim , Maucort‐Boulch Delphine , Minello Anne , Neau‐Cransac Martine , Pageaux Georges‐Philippe , Radenne Sylvie , Roux Olivier , Saliba Faouzi , Serée Olivier , Samuel Didier , Vanlemmens Claire , Woehl‐Jaegle Marie‐Lorraine , Leroy Vincent , Duclos‐Vallée Jean‐Charles , Dumortier Jérôme 
Published: February 2023

AbstractBackground & AimsAutoimmune hepatitis (AIH) is a rare indication for liver transplantation (LT). The aims of this study were to evaluate long‐term survival after LT for AIH and prognostic factors, especially the impact of recurrent AIH (rAIH).MethodsA multicentre retrospective nationwide study including all patients aged ≥16 transplanted for AIH in France was conducted. Early deaths and retransplantations (≤6 months) were excluded.ResultsThe study population consisted of 301 patients transplanted from 1987 to 2018. Median age at LT was 43 years (IQR, 29.4–53.8). Median follow‐up was 87.0 months (IQR, 43.5–168.0). Seventy‐four patients (24.6%) developed rAIH. Graft survival was 91%, 79%, 65% at 1, 10 and 20 years respectively. Patient survival was 94%, 84% and 74% at 1, 10 and 20 years respectively. From multivariate Cox regression, factors significantly associated with poorer patient survival were patient age ≥58 years (HR = 2.9; 95% CI, 1.4–6.2; p = 0.005) and occurrence of an infectious episode within the first year after LT (HR = 2.5; 95% CI, 1.2–5.1; p = 0.018). Risk factors for impaired graft survival were: occurrence of rAIH (HR = 2.7; 95% CI, 1.5–5.0; p = 0.001), chronic rejection (HR = 2.9; 95% CI, 1.4–6.1; p = 0.005), biliary (HR = 2.0; 95% CI, 1.2–3.4; p = 0.009), vascular (HR = 1.8; 95% CI, 1.0–3.1; p = 0.044) and early septic (HR = 2.1; 95% CI, 1.2–3.5; p = 0.006) complications.ConclusionOur results confirm that survival after LT for AIH is excellent. Disease recurrence and chronic rejection reduce graft survival. The occurrence of an infectious complication during the first year post‐LT identifies at‐risk patients for graft loss and death.
“Where Do I Even Start?”: Exploring Resources for Anthropology Students’ College‐to‐Career Transitions
Authors: Ding Emily , Storey Angela D. , Lee Brianna M. , Jhoslien Anastasia , Cora Maria 
Published: February 2023

AbstractThis article explores the resources that are available, or should be made available, to support college‐to‐career transitions for undergraduate anthropology students. Using mixed methods, this research was conducted by undergraduate anthropology students at a small Christian college in Illinois and at a large public university in Kentucky, in conjunction with a wider project for the American Anthropological Association. Based on our two case studies, we argue that students, faculty, and career centers often do not effectively work together to provide and utilize career resources for anthropology majors. This lack of collaboration leads to students feeling underresourced and undersupported. This is partially due to student disinclination to use career center resources but also a result of the way career centers present themselves to students and faculty's inattention toward facilitating a connection between them. We end with recommendations for departments, career centers, and students to facilitate resource availability and use.
Evolution of depressive symptoms from before to 24 months after bariatric surgery: A systematic review and meta‐analysis
Authors: Woods Robbie , Moga Ana M. , Ribeiro Paula A. B. , Stojanovic Jovana , Lavoie Kim L. , Bacon Simon L. 
Published: February 2023

SummaryAimsDepression after bariatric surgery can lead to suboptimal health outcomes. However, it is unclear how depressive symptoms evolve over the 24 months after surgery. We determined the extent depressive symptoms changed up to 24 months after bariatric surgery and how this was impacted by measurement tool and surgical procedure.MethodsWe conducted a systematic review and meta‐analysis, searching five databases from database inception to June 2021 for studies that prospectively measured depressive symptoms before and up to 24 months after bariatric surgery. Change scores were converted to Hedge's g, and analyses were performed using mixed‐effects models. Subgroup analyses examined differences across time of follow‐up, measurement tool, and surgical procedure.FindingsForty‐six studies met inclusion criteria (32,342 patients). Meta‐analysis indicated a postsurgical reduction in depressive symptom scores that were significant (large effect, g = 0.804; 95% CI: 0.73–0.88, I2 = 95.7%). Subgroup analyses found that symptom reductions did not differ between the timing of follow‐up periods, measurement tool, and surgical procedure.ConclusionsDepressive symptom scores reduced substantially following surgery; comparable decreases occurred 6 through 24 months after surgery. These findings can help inform practitioners of the typical evolution of depressive symptoms following surgery and where deviations from this may require additional intervention.
Potential effects of anticoagulants in preclinical mice models of oral cancer: A systematic review
Authors: Al‐Azzawi Huda Moutaz Asmael , Hamza Syed Ameer , Lin Zichen , Paolini Rita , McCullough Michael , Yap Tami , Celentano Antonio 
Published: February 2023

AbstractOral squamous cell carcinoma (OSCC) is the most common head and neck cancer. There is mounting evidence to suggest that several components of the coagulation system directly affect carcinogenesis. Our recent in vitro studies demonstrated, for the first time, that various anticoagulants have anticancer effects on OSCC. They also showed the need for the immediate translation of these experimental conditions from bench to preclinical animal models. Here, we carried out a systematic review to summarise existing evidence on murine models built around the interactions between anticoagulants and oral cancer. Only one preclinical murine study was included in our systematic review, investigating the role of heparins in tumour pathophysiology. The paucity of evidence regarding the interactions between oral squamous cell carcinoma and anticoagulants emphasises the urgency with which further preclinical research should be conducted.
The therapeutic perspective of cold atmospheric plasma in periodontal disease
Authors: Liu Zhixin , Du Xijin , Xu Lianyi , Shi Qi , Tang Xuezhi , Cao Yingguang , Song Ke 
Published: February 2023

AbstractObjectivesPeriodontal disease (PD) is one of the most common infectious diseases with complex inflammatory conditions, having irreversibly destructive impacts on the periodontal supporting tissues. The application of cold atmospheric plasma (CAP) is a promising adjuvant therapy modality for PD. However, the mechanism of CAP in PD treatment is still poorly understood. The review motivates to outline the latest researches concerning the applications of CAP in PD treatment.MethodsWe searched CAP‐related literature through utilizing the well‐established databases of Pubmed, Scopus and Web of Science according to the following keywords related to periodontal disease (periodontal, gingival, gingivitis, gingiva, periodontium, periodontitis).ResultsA total of 18 concerning original studies were found. These studies could be classified according to three pathophysiological perspectives of PD. The therapeutic mechanisms of CAP may be attributed to the oxidative stress‐related cell death of periodontal bacteria, the suppression of periodontal inflammation and pro‐inflammatory cytokine secretion, as well as the acceleration of periodontal soft tissue wound healing and hard tissue reconstruction.ConclusionsCold atmospheric plasma has potential therapeutic effects on PD through three mechanisms: antimicrobial effect, inflammation attenuation, and tissue remodeling. This review hopefully provides a comprehensive perspective into the potential of CAP in PD therapy.
Modulating Photochemical Properties to Enhance the Stability of Electronically Dimmable Eye Protection Devices†
Authors: Baburaj Sruthy , Parthiban Jayachandran , Rakhimov Sarvar Aminovich , Johnson Rasheedah , Sukhomlinova Ludmila , Luchette Paul , Jockusch Steffen , Forbes Malcolm D. E. , Sivaguru Jayaraman 
Published: February 2023

AbstractThe study evaluates compatibility of stabilizers with dye doped liquid crystal (LC) scaffolds that are used in electronically dimmable materials. The photodegradation of the materials was investigated and suitable stabilizers were evaluated to slow the degradation process. Various types of benzotriazole‐based stabilizers were evaluated for stabilizing the liquid crystals. Based on spin trapping experiments, radicals generated upon UV exposure is likely responsible for the degradation of the system. The radical generation is competitively inhibited by the addition of stabilizers.
New Measures for Family Planning and Exposure to Risk of Pregnancy Based on Sexual Activity and Contraceptive Use Data
Authors: Lee Chi Hyun , Susmann Herbert , Alkema Leontine 
Published: February 2023

AbstractFamily planning measures for unmarried women are based on contraceptive demand and use among sexually active women. Sexual activity status is commonly defined based on comparing reported time‐since‐last‐sex to a cutoff time, with women defined to be sexually active if their most recent sex was within the last four weeks. While easy to understand and compute, this approach to constructing family planning measures results in a limited understanding of family planning and exposure to unintended pregnancy because it cannot comprehensively capture the frequency of sex at the population level. We propose a new statistical approach to quantify sexual activity, using reported time‐since‐last‐sex data. Based on estimated frequencies of sex among users and nonusers in need of family planning, we propose new family planning measures, including the ratio of protected exposure over all women's exposure to risk of unintended pregnancy.
Healthcare resource utilization prior to suicide death or suicide attempt in patients with major depressive disorder—A Danish registry‐based cohort study
Authors: Jensen Kristoffer Jarlov , Osler Merete , Bødker Nikolaj , Riise Jesper , Petersen Janne 
Published: February 2023

AbstractIntroductionMajor depressive disorder (MDD) is associated with suicide events and with increased healthcare resource utilization (HRU). The aim was to analyze the pattern of HRU prior to death by suicide or suicide attempt in patients with MDD using national registries.MethodsDanish adults with MDD, who died by suicide or had a first‐time suicide attempt, were matched with MDD controls on age, sex, and MDD severity and analyzed for psychiatric and non‐psychiatric hospital and private practitioner contacts, and prescriptions 1 year prior to the event. For individuals having a second suicide attempt, HRU prior to first and second suicide attempt was analyzed.ResultsAmong 1061 individuals dying by suicide and 3759 individuals with suicide attempt, compared with their controls, the proportion with psychiatric hospitalization was more than 50% increased, mainly accounted for by acute contacts. The difference to the matched controls decreased with increasing MDD severity. Non‐psychiatric HRU was increased as well. The proportion with psychiatric hospitalizations or ED visits was reduced prior to the second attempt compared with first attempt.ConclusionAmong individuals with MDD, psychiatric and non‐psychiatric HRU was increased 1 year prior to suicide event. The proportion of individuals who had psychiatric HRU decreased from first to second suicide attempt.
Structural changes in humic substances after long‐term fertilization of a calcareous soil with pig slurries
Authors: Jiménez‐de‐Santiago Diana E. , Almendros Gonzalo , Bosch‐Serra Àngela D. 
Published: February 2023

AbstractPig slurries are widely used on calcareous soils in European rainfed systems. Here we assess their impact on the amount of soil organic carbon (SOC) and on the composition of humic‐type substances (HTS). Seven doses of slurry (five from fattening pigs and two from sows) ranging from 1.0 to 4.8 Mg ha−1 yr−1 of organic matter were evaluated after a period of 12 years and compared with mineral fertilizer treatment. At the end of the last annual cropping season (September), SOC was quantified, and HTS were isolated by alkaline extraction followed by acid precipitation, and studied by visible spectroscopy (800–400 nm) and Fourier‐transformed infrared spectroscopy (4000–400 cm−1). Following the trend in the slurry organic matter applied rates, SOC increased from 9.5 g C kg−1 (mineral treatment) to 13.8 g C kg−1. This SOC increase was equivalent to c. 25.4% of the slurry organic carbon applied. The incorporation of aliphatic structures, mainly polyalkyl, from slurries into the HTS tends to modify the composition of the soil organic matter (SOM), which is reflected in a decrease in the intensity of FT‐IR peaks related to aromatic structures. Despite the trend of significant increase in SOC with fattening slurries, mainly from the organic matter rate of 1.6 Mg ha−1 yr−1 (c. 185 kg N ha−1), the composition of the HTS showed an important aliphatic enhancement. The FTIR results showed that using exclusively the relative intensities of specific peaks (alkyl, carboxyl, aromatic and amide groups) as variables for the discriminant analysis, it is possible to identify HA between different groups of soils treated with progressive levels of slurry. Although the new aliphatic components could be considered important to improve soil physical quality, after the incorporation of additional SOM, the spectroscopic characteristics of HTS in soils treated with slurries suggested a weak effect in long‐term C sequestration, as the newly incorporated OC forms are not qualitatively similar to the presumably stable native SOM. These potential changes in SOC and SOM composition at field level are constrained by the maximum allowed N rates from organic origin in some agricultural systems.
Enumeration of regular maps of given type on twisted linear fractional groups
Authors: Mačaj Martin , Pavlíková Soňa , Širáň Jozef 
Published: February 2023

AbstractWe enumerate orientably regular maps of any given type with automorphism group isomorphic to a twisted linear fractional group; these groups form the ‘other’ family in Zassenhaus' classification of finite sharply 3‐transitive groups.
Realising sets of integers as mapping degree sets
Authors: Neofytidis Christoforos , Wang Shicheng , Wang Zhongzi 
Published: February 2023

AbstractGiven two closed oriented manifolds of the same dimension, we denote the set of degrees of maps from to by . The set always contains zero. We show the following (non‐)realisability results.

There exists an infinite subset of containing 0 which cannot be realised as , for any closed oriented ‐manifolds .
Every finite arithmetic progression of integers containing 0 can be realised as , for some closed oriented 3‐manifolds .
Together with 0, every finite geometric progression of positive integers starting from 1 can be realised as , for some closed oriented manifolds .
Knee movements cause changes in the firing behaviour of muscle spindles located within the mono‐articular ankle extensor soleus in the rat
Authors: Maas Huub , Noort Wendy 
Published: February 2023

AbstractWe recently showed that within an intact muscle compartment, changing the length of one muscle affects the firing behaviour of muscle spindles located within a neighbouring muscle. The conditions tested, however, involved muscle lengths and relative positions that were beyond physiological ranges. The aim of the present study was to investigate the effects of simulated knee movements on the firing behaviour of muscle spindles located within rat soleus (SO) muscle. Firing from single muscle spindle afferents in SO was measured intra‐axonally for different lengths (static) and during lengthening (dynamic) of the lateral gastrocnemius and plantaris muscles. Also, the location of the spindle within the muscle was assessed. Changing the length of synergistic ankle plantar flexors (simulating different static knee positions, between 45 and 130°) affected the force threshold, but not the length threshold, of SO muscle spindles. The effects on type II afferents were substantially (four times) higher than those on type IA afferents. Triangular stretch–shortening of synergistic muscles (simulating dynamic knee joint rotations of 15°) caused sudden changes in the firing rate of SO type IA and II afferents. Lengthening decreased and shortening increased the firing rate, independent of spindle location. This supports our prediction that the major point of application of forces exerted by connections between adjacent muscles is at the distal end of SO. We conclude that muscle spindles provide the CNS with information about the condition of adjacent joints that the muscle does not span.
Robust Design Optimization of Expensive Stochastic Simulators Under Lack-of-Knowledge
Authors: van Mierlo Conradus , Persoons Augustin , Faes Matthias G. R. , Moens David 
Published: February 2023

Abstract
Robust design optimization of stochastic black-box functions is a challenging task in engineering practice. Crashworthiness optimization qualifies as such problem especially with regards to the high computational costs. Moreover, in early design phases, there may be significant uncertainty about the numerical model parameters. Therefore, this paper proposes an adaptive surrogate-based strategy for robust design optimization of noise-contaminated models under lack-of-knowledge uncertainty. This approach is a significant extension to the robustness under lack-of-knowledge method (RULOK) previously introduced by the authors, which was limited to noise-free models. In this work, it is proposed to use a Gaussian Process as a regression model based on a noisy kernel. The learning process is adapted to account for noise variance either imposed and known or empirically learned as part of the learning process. The method is demonstrated on three analytical benchmarks and one engineering crashworthiness optimization problem. In the case studies, multiple ways of determining the noise kernel are investigated: (1) based on a coefficient of variation, (2) calibration in the Gaussian Process model, (3) based on engineering judgment, including a study of the sensitivity of the result with respect to these parameters. The results highlight that the proposed method is able to efficiently identify a robust design point even with extremely limited or biased prior knowledge about the noise.
Investigation of Mechanical Behaviors of Dental Implants With Different Geometries
Authors: Yuan Zhongxiao , Chong Perk Lin , Roy Sandipan , Merdji Ali , Ouldyerou Abdelhak , Faraji Foad , Moey Lip Kean , Yazdi Mohammad Hossein , Mukdadi Osama M. 
Published: February 2023

AbstractDental implants have received a lot of attention and have been used to treat symptoms such as missing teeth and bad teeth. Due to the wide range of occupations and ages of patients, the functions and aims of implants are different. There are many kinds of dental implant shapes. However, with the popularity of dental implants, the problems caused by the some of the dental implant shapes have received much attention. In fact, some implants were used incorrectly. This makes the stress distribution around the implant unreasonable; it not only affects the surrounding bone resorption but also causes mechanical fracture of the implant. This work aims to evaluate the mechanical features of five different kinds of dental implant systems. By applying engineering systems of investigations such as FEM, five types of dental implants and surrounding bone tissue were modeled and simulated under vertical loads of 90 N. Distributions of stresses and deformations in the bone were obtained and ranked according to statistical scores, which were used to judge the optimum geometry of implants. The analytical results showed that the cylindrical implant is the most optimum shape among the other types of implants.
Unconditionally Stable Numerical Scheme for Heat Transfer of Mixed Convective Darcy–Forchheimer Flow of Micropolar Fluid Over Oscillatory Moving Sheet
Authors: Nawaz Yasir , Arif Muhammad Shoaib , Abodayeh Kamaleldin 
Published: February 2023

AbstractThis contribution proposes a third-order numerical scheme for solving time-dependent partial differential equations (PDEs). This third-order scheme is further modified, and the new scheme is obtained with second-order accuracy in time and is unconditionally stable. The unconditional stability of the new scheme is proved by employing von Neumann stability analysis. For spatial discretization, a compact fourth-order accurate scheme is adopted. Moreover, a mathematical model for heat transfer of Darcy–Forchheimer flow of micropolar fluid is modified with an oscillatory sheet, nonlinear mixed convection, thermal radiation, and viscous dissipation. Later on, the dimensionless model is solved by the proposed second-order scheme. The results show that velocity and angular velocity have dual behaviors by incrementing coupling parameters. The proposed second-order accurate in-time scheme is compared with an existing Crank–Nicolson scheme and backward in-time and central in space (BTCS) scheme. The proposed scheme is shown to have faster convergence than the existing Crank–Nicolson scheme with the same order of accuracy in time and space. Also, the proposed scheme produces better order of convergence than an existing Crank–Nicolson scheme.