bluuebunny/crossref_metadata_2025_split huggingface dataset:
Treatment options for patients with overlap of functional dyspepsia and irritable bowel syndrome
Authors: Dorofeyev A. E. , Tkach S. M. , Gurkalo Y. Z. , Kugler T. E. , Zhigal Y. V. , Chichula Y. V. 
Published: March 2023

Оbjective — to study the characteristics of changes in intestinal dysbiosis and psychoemotional status in patients with overlap of functional dyspepsia (FD) and irritable dowel syndrome (IBS) and to evaluate the efficacy of peppermint oil application in the treatment of such patients.
Materials and methods. Examinations involved 92 patients with overlap of FD and IBS, from them 35 (38.0 %) men and 57 (62.0 %) women. Young patients (up to 45 years old) prevailed: 72 subjects (78.3 %). Epigastric pain syndrome was detected in 12 (13.0 %) patients, postprandial distress syndrome in 21 (22.8 %) patients, and 59 (64.1 %) patients had a mixed FD form. IBS with alternating constipation and diarrhea was diagnosed in 51 out of 59 (86.4 %) patients with the mixed FD form. Psychological testing was conducted to assess the psycho‑emotional status. The HADS scale was used to detect anxiety‑depressive disorders. Before and after treatment, all patients completed the SF‑36 quality of life (QoL) questionnaires. To diagnose the condition of the intestinal microbiota, presence of bacterial intestinal overgrowth syndrome (SIBO) was determined with the use of a hydrogen breath test with lactulose loading.
Results. The use of the drug «Capsumen» in the complex treatment of patients with FD and IBS contributed to a rapid decrease in the intensity of abdominal pain (AP) (p < 0.05). In addition to positive clinical dynamics and AP relief, normalization of the intestinal microbiome was found in the patients. The SIBO frequency in patients who received «Capsumen» significantly decreased compared to the initial indexes and did not significantly differ from the data of healthy individuals. In all patients with FD and IBS, on the background of therapy, quality of life increased and anxiety‑depressive disorders decreased, compared to the data before treatment (p < 0.05).
Conclusions. The use of peppermint oil in patients with FD and IBS demonstrated to be efficient and safe. The decrease in the abdominal pain frequency and intensity has been registered, in combination with the positive effects on the intestinal microbiome and normalization of quality of life, and minimizing anxiety‑depressive disorders.
Meningkatkan Aktivitas Belajar Siswa Kelas V Menggunakan Alat Peraga IPA Sistem Pernapasan Manusia di SD Islam Nurul Huda Jatipulo Jakarta
Authors: Pratiwi Neisya , Syofyan Harlinda 
Published: March 2023

This research is motivated by learning activities, enthusiasm, and interest in learning owned by fifth-grade students at SD Islam Nurul Huda Jatipulo has decreased, especially in science subjects due to reduced student interest in learning, and less interesting ways of learning so that students are easily bored learning. The purpose of this class action research is to increase the learning activities of fifth-grade students with the use of science props Human respiratory system. The subjects of this class action research are fifth-grade students of SD Islam Nurul Huda Jatipulo Jakarta 2022/2023. The research subjects totaled 15 students consisting of 7 male students and 8 female students. The type of research used is classroom action research (PTK) which includes several cycles consisting of stages such as planning, action, observation, and reflection. The data analysis techniques used were descriptive qualitative and descriptive quantitative. The results of this study are that in cycle I the percentage of the number of students who met the good category was only 20%, then increased to 80% in cycle II. The average percentage of student learning activities in each aspect continued to increase in cycle I with an average percentage of 43% which then increased in cycle II with an average percentage of 87%.
Improving Cross-Cultural Comparability of Measures on Gender and Age Stereotypes by Means of Piloting Methods
Authors: Menold Natalja , Hadler Patricia , Neuert Cornelia 
Published: March 2023

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<p>The study addresses the effects of piloting methods on the reliability and cross-cultural comparability of the measurement of stereotypes. A gender roles instrument from the European Values Study, an ageism instrument, and children stereotypes from the International Social Survey Program were piloted in German and American English and revised based on findings from cognitive interviews, web probing, and expert reviews involving national experts or additionally cross-cultural experts. The original and each piloted version were randomly assigned to respondents in Germany and the U.S. using an online survey and quota samples. The original gender roles and children stereotypes instruments did not face configural invariance and reliability was insufficiently low. The results show that piloting methods can increase insufficient reliability. Measurement invariance could be improved by piloting methods, but effects varied by the type of revisions implemented. Cross-cultural expert reviews and web probing provided more consistent results than other methods. A combination of methods would be optimal to improve reliability and measurement invariance. </p>
Investigation of the effect of perineural invasion on survival rates in rectal tumors.
Authors: OZGEN Utku , SUNGURTEKİN Uğur , DEMİRKAN Neşe 
Published: March 2023

Purpose: Colorectal cancers compose the third most common cancer group leading to death, with increasing rates in developed countries after lung and breast cancers. Rectal cancers make up about 30% of all colorectal cancers. Although many factors affecting recurrence and survival in rectal cancer have been identified, the stage of the tumor is the most important prognostic factor. However, many additional parameters that can be associated with survival and affect the adjuvant treatment plan have been identified besides the stage. Perineural invasion (PNI) is one of the parameters that can be associated with survival and affect the adjuvant treatment plan in colorectal cancers. The aim of this study is to investigate the effects of various histopathological prognostic factors, including PNI, on disease-free survival, overall survival, and recurrence rates in patients with rectal cancer who underwent surgery. Materials and methods: The clinical records of patients diagnosed with rectal cancer and operated on at the Department of General Surgery, Faculty of Medicine, Pamukkale University between 2008-2014 were reviewed. To investigate the factors affecting disease-free survival, recurrence rates, and overall survival, the presence of PNI, serum CEA levels, cTNM stage, pT stage, pN stage, number of metastatic LNs, tumor budding status, histopathological grades, lymphocyte infiltration, and presence of desmoplasia were evaluated in patients.
Results: A total of 124 patients were included in the study. 42 patients (33.9%) had PNI while 82 patients (66.1%) did not have PNI. Of the 45 patients with recurrence, 26 had PNI while 19 did not have PNI. Of the 79 patients without recurrence, 16 had PNI while 63 did not have PNI. Similarly, PNI was seen more frequently in deaths related to the disease. The 3-year average survival of patients with and without PNI was 55% and 89%, respectively (p
The Effects of Online Learning Transition during the COVID-19 Pandemic in Pakistan
Authors: Shahid Shiza , Shahid Amina 
Published: March 2023

Amidst the global pandemic of Covid-19, online learning has been widely used around the country. Teachers’ and students' experiences related to online learning have been explored in this study through the online survey method. This was a novel experience for teachers and students as both groups were not familiar with this mode of education. Hence, it was imperative to explore their experiences with online learning amidst a pandemic. The data for this study was collected from public and private universities of Faisalabad and Lahore. A total of 430 participants (N=100 teachers & N= 330 students) from Faisalabad and Lahore's colleges and universities were included in the study. The data was gathered using an online survey. The following areas were found to be crucial to the satisfaction of both teachers and students in online classes. Student-faculty contact, technical assistance, organized online classes, and adaptations to enable practical classes were all incorporated in these areas. Since then, this research has focused on a dynamic phenomenon that includes several facets of online learning.
Karakteristik Ekologi Ekosistem Mangrove di Perairan Estuari Sei Carang Kota Tanjungpinang, Kepulauan Riau
Authors: Zakia Rahima , Lestari Febrianti 
Published: March 2023

Kawasan Perairan Estuari Sei Carang memiliki ekosistem mangrove yang merupakan habitat penting bagi biota yang ada didalamnya serta memiliki peranan sebagai pelindung kawasan pesisir dari hempasan angin, arus dan ombak dari laut, serta berperan juga sebagai benteng dari pengaruh banjir dari daratan. Penelitian ini bertujuan untuk mengetahui karakteristik ekologi ekosistem mangrove di Perairan Estuari Sei Carang Kota Tanjungpinang. Penelitian ini dilaksanakan pada bulan Oktober hingga Desember 2021 yang berlokasi di Perairan Estuari Sei Carang. Lokasi pengamatan ditentukan menggunakan metode survey dengan pemilihan titik sampling menggunakan purposive sampling. Karakteristik ekologi ekosistem mangrove yang diamati yaitu sebaran jenis, kerapatan, persentase tutupan serta parameter perairan meliputi suhu, pH, salinitas, DO, substrat, dan tipe pasang surut. Beberapa jenis mangrove yang dijumpai pada Perairan Estuari Sei Carang diantaranya Rhizophora apiculata, Rhizophora mucronata, Rhizophora lamarckii, Bruguiera gymnorrihiza, Bruguiera sexangula, Sonneratia alba, Xylocarpus granatum, Ceriops tagal, Lumnitzera littorea dan Avicennia marina Rata-rata kerapatan serta persentase tutupan mangrove di Perairan Sei Carang berada pada kategori padat yang menunjukkan bahwa kerapatan serta persentase tutupan masuk ke dalam kriteria sedang dan hal ini menunjukkan kondisi mangrove masih dalam keadaan baik. Berdasarkan hasil analisis data kerapatan dan persentase tutupan mangrove stasiun 1 memiliki nilai yang paling tinggi dengan nilai kerapatan 4467 ind/Ha dan persentase tutupan sebesar 82,8%.
СОЦІАЛЬНОКОМУНІКАЦІЙНА КОНЦЕПЦІЯ ПРОПАГАНДИ ФАШИЗМУ С. ЧАХОТІНА: ПРОЄКЦІЯ НА «РАШИЗМ»
Authors: Bondarenko I. 
Published: March 2023

<p><strong><em>The purpose</em></strong><em> of the article is the analysis and representation of the unexplored scientific heritage of S. Chakhotin, in particular, the concept of the psychological impact of political propaganda.</em></p><p><strong><em>Research methodology.</em></strong> <em>In the process of studying the model of the psychological impact of political propaganda, the methods of analysis and synthesis were applied – to mark and differentiate the basic concepts of the communication process; the Grounded theory methodology made it possible to collect and analyze factual material to determine the social and communication specifics of S.</em><em> </em><em>Chakhotin’s theory; the social engineering approach made it possible to determine the technological resource of communication technologies.</em></p><p><strong><em>The results.</em></strong><em> S. Chakhotin distinguished two forms of political propaganda – «rational propaganda» or «scientific propaganda», based on the intelligent use of information resources, and «retroactive» or «violent» propaganda that uses the mechanism of total aggression. At the same time, the techniques of effective political propaganda in both the first and second cases are identical. The communication basis of this technology has a pyramidal structure: the basis is a philosophical teaching (for example, Marxism), the next concept is a political program, then a slogan, and the top of the pyramid is a graphic symbol. The researcher made interesting comments about the technology of promoting graphic symbols among the masses.</em></p><p><strong><em>Novelty.</em></strong><em> The article presents an unexplored concept of the psychological impact of political propaganda on the masses of S. Chakhotin; theoretical aspects of teaching are superimposed on modes of Russian propaganda.</em></p><p><strong><em>Practical importance.</em></strong><em> The results of the article can be used in the educational process of a higher school, as well as in the reconstruction of the historical foundations of the development of the science of social communications. </em></p><p><strong><em>Key words:</em></strong><em> influence, masses, narrative, crowd, symbol, social engineering, propaganda, advertising.</em></p>
Studi Kualitatif Fungsi Internal Audit dan Manajemen Risiko Dalam Tata Kelola Perguruan Tinggi Swasta
Authors: Saputra Tedy Setiawan , Ismandra Ismandra 
Published: March 2023

The study aims to measure the role and function of internal audit and risk management as a part of good university governance on private higher education in Palembang City. The current phenomenon is both of the department function is run by quality assurance. The implementation is based on the rule of the perkemendikbud No 50 in the year 2014. The research utilized a qualitative method. Data were obtained from five private universities in Palembang city by spreading the open questionnaire form. The data was analyzed and supported by Nvivo 12 application. The results of data analysis show that the role and function of internal audit and risk management are not optimal yet. Optimized the function, has resulted in the design of organization chart changes by considering the current regulation and any standards.

Keywords: Internal Audit, Risk Management, Higher Education, Qualitative, Good University Governance

Abstrak
Tujuan dari penelitian ini adalah untuk menilai penerapan fungsi Internal Audit dan Manajemen Risiko sebagai bagian dari penerapan tata kelola perguruan tinggi swasta di kota Palembang. Fenomena yang terjadi saat ini, peranan dan fungsi internal audit serta manajemen risiko dijalankan oleh Lembaga Penjamin Mutu secara bersamaan. Penerapan fungsi ini mengacu kepada permendikbud No.50 tahun 2014. Penelitian ini menggunakan metode kualitatif. Data diperoleh dari lima Perguruan Tinggi swasta di Kota Palembang dengan melakukan wawancara berdasarkan kuesioner terbuka. Data hasil wawancara dianalisis menggunakan aplikasi Nvivo 12. Hasil analisis menunjukkan bahwa peranan dan fungsi internal audit serta manajemen risiko pada perguruan tinggi swasta di Palembang belum optimal. Untuk mengoptimalkan peranan dan fungsi internal audit dan manajemen risiko, dihasilkan sebuah rancangan perubahan struktur organiasi kedua fungsi dengan mempertimbangkan regulasi dan standar yang berlaku.

Kata kunci: Internal Audit, Manajemen Risiko, Pendidikan Tinggi, Kualitatif. Tata Kelola Perguruan Tinggi
Analisis Tingkat Technostress Tenaga Kerja Sektor Perbankan Di Kota Palembang Selama Pandemi Covid-19
Authors: Mellita Dina , Rizqullah Bahi Achmad Syafi 
Published: March 2023

The purpose of this study was to determine Technostress in the banking sector workforce in Palembang City. This research uses a quantitative descriptive study design, in which researchers describe the level of technostress among banking workers as a result of the use of information technology and digitalization during the pandemic. The level of technostress is identified through the variables Techno-Overload, Techno-Invasion, Techno-Complexity, Techno-Insecurity and Techno-Uncertainty. Based on the results of the research and analysis, it can be concluded that the levels of technostress experienced by banking sector workers in Palembang during the pandemic were in the medium and high categories. Based on the results of interviews, stress levels were in both the medium and high categories experienced by young people (24-29 years and 35-39 years). By identifying the level of technostress based on gender, it is known that both in the medium and high categories the level of stress as a result of using technology is experienced more by women both in the Techno-Overload, Techno-Invasion, Techno-Complexity, Techno-Insecurity and Techno-Uncertainty variables. Based on the status of the place of work, the highest distribution at the technostress level was experienced by respondents who worked in state-owned banks

Keywords: Technostress, Techno-Overload, Techno-Invasion, Techno-Complexity, Techno-Insecurity and Techno-Uncertainty

Abstrak
Tujuan dilakukan penelitian ini adalah untuk mengetahui Technostress pada tenaga kerja sektor perbankan di Kota Palembang. Penelitian ini menggunakan rancangan studi deskriptif kuantitatif, dimana peneliti melakukan deskripsi tingkat technostress di kalangan pekerja perbankan sebagai akibat penggunaan teknologi informasi dan digitalisasi selama pandemic berlangsung. Tingkat technostress diidentifikasi melalaui variable-variabel Techo-Overload, Techno-Invasion, Techno-Complexity, Techno-Insecurity dan Techno-Uncertainty. Berdasarkan hasil penelitian dan analisis, dapat disimpulkan bahwa ingkat technostress yang dialami para pekerja sektor perbankan di Kota Palembang selama pandemic berada pada kategori sedang dan tinggi. Berdasarkan hasil wawancara, tingkat stress berada pada baik pada kategori sedang dan tinggi dialami oleh usia muda (24-29 tahun dan 35-39 tahun). Melalui identifikasi tingkat technostress berdasarkan gender, diketahui bahwa baik pada kategori sedang dan tinggi tingkat stress sebagai akibat penggunaan teknologi lebih banyak dialami oleh perempuan baik pada variable Techno-Overload, Techno-Invasion, Techno-Complexity, Techno-Insecurity dan Techno-Uncertainty. Berdasarkan status tempat pekerjaan, distribusi tertinggi pada tingkat technostress dialami oleh responden yang bekerja pada perbankan milik pemerintah

Kata Kunci: Technostress, Techno-Overload, Techno-Invasion, Techno-Complexity, Techno-Insecurity and Techno-Uncertainty
Analisis Pengaruh CSRD terhadap Manajemen Laba : Moderasi Kepemilikan Keluarga yang Terdaftar di Bursa Efek Indonesia
Authors: Destiana Destiana , Karina Ria 
Published: March 2023

This research examines the effect of Disclosure CSR on earning management moderated by Family Ownership. This examination measures Disclosure CSR by Global Reporting Initiative (GRI) 2021. This research used 5 (five) variable control: firm size, leverage, sales growth, NI and company age. Data used in this research is derived from annual reports listed on the Indonesia Stock Exchange in 2017-2021. By using purposive sampling, there are 128 company samples. The analysis methodology for this research was a regression test. The results show that CSRD significantly affects earning management negatively, as well as family ownership. Moderation of family ownership has reinforced the negative effect on the relationship between CSRD and earning management.

Keywords: CSRD, Earning Management, Family Ownership

Abstrak
Penelitian ini bertujuan untuk memahami hubungan pengungkapan CSR terhadap earning management yang dimoderasi oleh kepemilikan keluarga. Pengungkapan CSR untuk penelitian ini diukur dengan indeks Global Reporting Initiative (GRI) 2021. Data yang digunakan dalam penelitian ini adalah data sekunder yang berasal dari laporan tahunan yang terdaftar di Bursa Efek Indonesia (BEI) periode 2017-2021, dan sampel sebanyak 128 perusahaan diperoleh dengan menggunakan metode purposive sampling. Metode analisis data yang digunakan dalam penelitian ini adalah uji regresi. Akibatnya, ditemukan bahwa CSRD memiliki efek negatif pada earning management. Kepemilikan keluarga berpengaruh negatif terhadap earning management. Moderasi dalam kepemilikan keluarga memperkuat hubungan negatif antara CSRD dan earning management.

Kata kunci: CSRD, Manajemen Laba, Kepemilikan Keluarga
Pengaruh Profitabilitas, Solvabilitas, Likuiditas, Ukuran Perusahaan, Leverage Dan Opini Auditor Terhadap Audit Report Lag
Authors: Meirawati Eka , Relasari Relasari , Budiman Anton Indra , Efriandy Iwan 
Published: March 2023

This study aims to analyze and obtain empirical evidence regarding the effect of profitability, solvency, liquidity, firm size, leverage, and auditor's opinion on audit report lag. The type of data used in this study is secondary data in the form of the company's annual financial reports. The research population is all property and real estate sector companies listed on the Indonesia Stock Exchange (IDX) in 2017-2020. Number of property and real estate sector companies listed on the Indonesia Stock Exchange during 2017-2020. totaling 65 companies. The method used is a non-probability sampling technique which means it is a technique that does not provide equal opportunities for all elements or parts of the population to be selected as samples. The analytical technique used is multiple linear regression analysis using the SPSS program. with the results of his research that profitability, company size, and auditor's opinion have an effect on audit report lag.
Keywords: Audit Report Lag, Profitability, Solvency, Liquidity, Company Size, Auditor Opinion

Abstrak
Penelitian ini bertujuan untuk menganalisa dan memperoleh bukti empiris mengenai pengaruh profitabilitas, solvabilitas, likuiditas, ukuran perusahaan, leverage,dan opini auditor terhadap audit report lag. Jenis data yang digunakan pada penelitian ini adalah data sekunder berupa laporan keuangan tahunan perusahaan. Populasi penelitian adalah semua perusahaan sektor property dan real estate yang terdaftar di Bursa Efek Indonesia (BEI) pada tahun 2017-2020. Jumlah Perusahaan sektor porperty dan real estate yang terdaftar di Bursa Efek Indonesia selama tahun 2017-2020. berjumlah 65 perusahaan. Metode yang digunakan adalah teknik nonprobability sampling yang berarti merupakan teknik yang tidak memberi peluang yang sama untuk semua unsur atau bagian populasi untuk dipilih menjadi sampel.Teknik analisis yang digunakan adalah uji analisis regresi linear berganda dengan menggunakan program SPSS, dengan hasil penelitiannya bahwa profitabilitas, ukuran perusahaan, dan opini auditor berpengaruh terhadap audit report lag
Kata Kunci : Audit Report Lag, Profitabilitas, Solvabilitas, Likuiditas, Ukuran Perusahaan, Opini Auditor
Primary human organoids models: Current progress and key milestones
Authors: Calà Giuseppe , Sina Beatrice , De Coppi Paolo , Giobbe Giovanni Giuseppe , Gerli Mattia Francesco Maria 
Published: March 2023

During the past 10 years the world has experienced enormous progress in the organoids field. Human organoids have shown huge potential to study organ development, homeostasis and to model diseases in vitro. The organoid technology has been widely and increasingly applied to generate patient-specific in vitro 3D cultures, starting from both primary and reprogrammed stem/progenitor cells. This has consequently fostered the development of innovative disease models and new regenerative therapies. Human primary, or adult stem/progenitor cell-derived, organoids can be derived from both healthy and pathological primary tissue samples spanning from fetal to adult age. The resulting 3D culture can be maintained for several months and even years, while retaining and resembling its original tissue’s properties. As the potential of this technology expands, new approaches are emerging to further improve organoid applications in biology and medicine. This review discusses the main organs and tissues which, as of today, have been modelled in vitro using primary organoid culture systems. Moreover, we also discuss the advantages, limitations, and future perspectives of primary human organoids in the fields of developmental biology, disease modelling, drug testing and regenerative medicine.