bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mg2+ Ion Pre‐Insertion Boosting Reaction Kinetics and Structural Stability of Ammonium Vanadates for High‐Performance Aqueous Zinc‐Ion Batteries
Authors: Tang Han , Chao Feiyang , Luo Hongyu , Yu Kesong , Wang Juan , Chen Huibiao , Jia Runmin , Xiong Fangyu , Pi Yuqiang , Luo Ping , An Qinyou 
Published: April 2023

AbstractAqueous zinc‐ion batteries (AZIBs) attract much attention owing to their high safety, environmentally friendliness and low cost. However, the unsatisfactory performance of cathode materials is one of the unsolved important factors for their widespread application. Herein, we report NH4V4O10 nanorods with Mg2+ ion preinsertion (Mg‐NHVO) as a high‐performance cathode material for AZIBs. The preinserted Mg2+ ions effectively improve the reaction kinetics and structural stability of NH4V4O10 (NHVO), which are confirmed by electrochemical analysis and density functional theory calculations. Compared with pristine NHVO, the intrinsic conductivity of Mg‐NHVO is improved by 5 times based on the test results of a single nanorod device. Besides, Mg‐NHVO could maintain a high specific capacity of 152.3 mAh g−1 after 6000 cycles at the current density of 5 A g−1, which is larger than that of NHVO (only exhibits a low specific capacity of 30.5 mAh g−1 at the same condition). Moreover, the two‐phase crystal structure evolution process of Mg‐NHVO in AZIBs is revealed. This work provides a simple and efficient method to improve the electrochemical performance of ammonium vanadates and enhances the understanding about the reaction mechanism of layered vanadium‐based materials in AZIBs.
Global differences in acute heart failure treatment: analysis of the STRONG‐HF site feasibility questionnaire
Authors: Novosadova Maria , Gianchetti Lauren , Takagi Koji , Morishetty Priyanka , Gaeta Lauren , Edwards Christopher , Davison Beth A. , Picod Adrien , Mebazaa Alexandre , Cotter Gad 
Published: April 2023

AbstractAimsAcute heart failure (AHF) has an impact on human health worldwide. Despite guidelines for treatment and management of AHF, mortality rates remain high. The main objective of this study was to compare standard in‐hospital treatment and management of AHF against current clinical guidelines and variations across regions.MethodsBetween February 2018 and May 2021, investigators were approached to participate in the STRONG‐HF study. The lead investigator at 158 sites in 20 countries completed a site feasibility questionnaire. Sites were grouped by country into five different regions: Africa and the Middle East, Eastern Europe, Russia, South America, and Western Europe.ResultsAccording to the questionnaires, there are large differences in how patients present due to AHF and where in the hospital they are treated. There were significant differences in reported percentage of AHF patients receiving angiotensin converting enzymes inhibitors across the regions (P < 0.001), mostly due to prescription of more angiotensin II receptor blockers and angiotensin receptor‐neprilysin inhibitors in South America and Western Europe. Reported beta‐blocker use was high across all of the regions. Device therapy and percutaneous interventions were more common in Europe. Sites reported a 5 to 8 day length of stay, while in Russia most have a 10 to 12 day length of stay. Regions reported that AHF patients follow up with a community cardiologist or general practitioner post‐discharge, although follow‐up was commonly more than 1 month post discharge, and not all sites had the capability to measure natriuretic peptides post discharge.ConclusionsIn this analysis of feasibility questionnaires, most sites reported general adherence to ESC guidelines for treatment and management of AHF patients although percutaneous and device therapy was less common outside Europe and follow‐up after discharge took place late and was not as extensive as recommended. There were wide variations seen within and across regions in some areas.
Polyamides Derived from Terpenes: Advances in Their Synthesis, Characterization and Applications
Authors: Winnacker Malte 
Published: April 2023

AbstractPolyamides are very important polymers, with applications from commodities up to high‐performance materials for, for example, fibers or for the biomedical sector. Nowadays, still most of them are synthesized from fossil resources. With regards to sustainability and bioeconomy, and especially regarding the new structures and properties that can thus be achieved, the preparation of polyamides (PAs) from natural precursors is getting more and more important. For this, especially the utilization of terpenes, a large and important group of natural products with different functions in nature (regulators, defense signals, etc.), is important, which is described herein. Similar approaches are interesting from a scientific point of view regarding, for example, structure‐function‐relations, but also with regards to different applications as, for example, high‐performance or biomedical materials.Practical applications: Terpene‐based polyamides can find many applications, from commodities up to high‐performance fibers and special materials in (bio)medicine, for example, drug delivery, tissue engineering, etc.
Influence of carbon on the dynamic changes in Co oxidation state of Ba0.5Sr0.5Co0.8Fe0.2O3‐δ perovskite catalyst during the oxygen reduction and evolution reactions
Authors: Beall Casey E. , Fabbri Emiliana , Clark Adam H. , Yüzbasi Nur Sena , Graule Thomas , Schmidt Thomas J. 
Published: April 2023

AbstractCarbon is often used as a conductive additive in catalyst layers to increase conductivity and catalytic activity. However, the effect of carbon addition to perovskites on the oxygen reduction (ORR) and oxygen evolution (OER) reactions is convoluted. In this work, composites of perovskite Ba0.5Sr0.5Co0.8Fe0.2O3‐δ (BSCF) and conductive additives, carbon and indium doped tin oxide are compared. It is found that the conductive additives have differing effects on the ORR and OER activities and cobalt redox behavior, with carbon having a much more significant effect. In order to elucidate further these differences between BSCF and BSCF/carbon, operando X‐ray absorption spectroscopy (XAS) is measured simultaneously with cyclic voltammetry into the ORR and OER regions and the continuous changes in the Co oxidation state are observed with high time resolution. We theorize that carbon is enhancing the Co redox activity and as a result, the ORR and OER activities are likewise improved.image
Application of response surface approach to optimize CI engine parameters fuelled by newly developed waste cooking biodiesel infused with Al2O3 nanoparticle
Authors: Bhan Suraj , Gautam Raghvendra , Singh Pushpendra 
Published: April 2023

AbstractIn the present study, newly developed waste cooking biodiesel (B20) with nanoparticles (Al2O3) was tested to optimize the response of a CRDI single‐cylinder four‐stroke VCR engine at various input parameters. A response surface methodology (RSM) was used to investigate the impact of various input parameters, such as injection pressure (IP), load, compression ratio (CR), and nanoparticle concentration as fuel additives on engine responses, including brake thermal efficiency (BTE), specific fuel consumption (SFC), carbon dioxide (CO), hydrocarbon (HC), and oxide of nitrogen (NOX) emissions. The RSM found the best suitable value of all input parameters at which the engine produced maximum performance and minimum emissions. Accordingly, the optimal setting of all input parameters was identified as a nano biofuel blend ratio of 1.10, IP of 656 bar, CR of 18.50, and a load of 7.10 kg. At this combination of input parameters, the optimal BTE, SFC, CO, HC, and NOx are 23.6%, 0.3461 kg/kWh, 0.0281%, 25.3756 ppm, and 536.41 ppm respectively. The predicted optimum value from RSM is compared with the experimental value for validity and found a fair agreement.
Energy‐compatible modulating functions for the stochastic generation of fully non‐stationary artificial accelerograms and their effects on seismic site response analysis
Authors: Genovese Federica , Biondi Giovanni , Cascone Ernesto , Muscolino Giuseppe 
Published: April 2023

AbstractThe reliability of non‐linear dynamic analysis aimed to predict the seismic performance of structural and geotechnical systems, as well as their dynamic interaction, is significantly affected by the selection of suitable input motions. Several procedures for selecting actual earthquake records compatible with the seismic hazard at the site of interest and for evaluating synthetic accelerograms consistent with a seismological framework are available in the literature. However, the degree of uncertainty affecting these approaches might lead to unreliable performance predictions especially for strongly non‐linear problems, such as those involving the response of soils to cyclic and dynamic loading. In this vein, the paper presents a procedure for generating fully non‐stationary ground motions ensuring energy compatibility with a target motion. Two different approaches have been introduced: i) the time window method based on the central finite difference approach and ii) the simplified intensity‐compatible approach in which a closed form expression is provided to evaluate a modulating function that depends on the Arias intensity and on the strong motion duration of a target motion. To highlight the reliability and the accuracy of the proposed procedure, several sets of spectrum‐compatible artificial accelerograms, generated starting from a rock outcropping motion, were used as input motions in a series of one‐dimensional site response analyses. The analysis results are presented and discussed in the paper highlighting the influence of the main features of the proposed generation procedure on the variability of the computed site response.
Wrestling with Social and Behavioral Genomics: Risks, Potential Benefits, and Ethical Responsibility
Authors: Meyer Michelle N. , Appelbaum Paul S. , Benjamin Daniel J. , Callier Shawneequa L. , Comfort Nathaniel , Conley Dalton , Freese Jeremy , Garrison Nanibaa' A. , Hammonds Evelynn M. , Harden K. Paige , Lee Sandra Soo‐Jin , Martin Alicia R. , Martschenko Daphne Oluwaseun , Neale Benjamin M. , Palmer Rohan H. C. , Tabery James , Turkheimer Eric , Turley Patrick , Parens Erik 
Published: April 2023

AbstractIn this consensus report by a diverse group of academics who conduct and/or are concerned about social and behavioral genomics (SBG) research, the authors recount the often‐ugly history of scientific attempts to understand the genetic contributions to human behaviors and social outcomes. They then describe what the current science—including genomewide association studies and polygenic indexes—can and cannot tell us, as well as its risks and potential benefits. They conclude with a discussion of responsible behavior in the context of SBG research. SBG research that compares individuals within a group according to a “sensitive” phenotype requires extra attention to responsible conduct and to responsible communication about the research and its findings. SBG research (1) on sensitive phenotypes that (2) compares two or more groups defined by (a) race, (b) ethnicity, or (c) genetic ancestry (where genetic ancestry could easily be misunderstood as race or ethnicity) requires a compelling justification to be conducted, funded, or published. All authors agree that this justification at least requires a convincing argument that a study's design could yield scientifically valid results; some authors would additionally require the study to have a socially favorable risk‐benefit profile.
Mapping breastfeeding and COVID‐19 related content and engagement on Facebook: Results from an online social listening study
Authors: White Becky K. , Burns Sharyn K. , Carson Jennie , Scott Jane A. 
Published: April 2023

AbstractIssue addressedThe COVID‐19 pandemic has seen evidence and advice evolve quickly. Since the start of the pandemic there has been confusion and concern about breastfeeding and COVID‐19, and advice for this group has at times been contradictory. The volume of information on social media has exacerbated this. This study aimed to understand breastfeeding‐related COVID‐19 information sharing on social media during the global and Australian vaccine roll‐out.MethodsThe CrowdTangle platform was used to source data from December 2020 to December 2021. Posts were categorised to intent and source and mapped to a timeline of pandemic‐related events and announcements. Descriptive analysis was used to understand data distribution patterns and qualitative analysis for post‐intent.ResultsA total of 945 posts were included. Post‐interactions ranged from 0 to 6500. Vaccine‐related posts were the highest in number and increased over time. Non‐profit organisations shared the highest number of posts (n = 241), but interactions were highest with personal and government accounts. Peaks in posts and interactions mapped to key pandemic‐related announcements and events.ConclusionThese results describe the breastfeeding and COVID‐19 related content shared on Facebook over 13 months, and the associated interactions. Breastfeeding is an important public health issue and breastfeeding women have experienced conflicting and confusing breastfeeding‐related information during the COVID‐19 pandemic. Better understanding of social media usage, and the monitoring of changes in usage, as an emergency unfolds, can help target communications. This article adds to the evidence in understanding user reactions to COVID‐19 related breastfeeding information on social media.So what?Social listening is an important part of health communication and infodemic management. Understanding how users react to and engage with COVID‐19 related breastfeeding information on social media can help to understand how the general public perceives and responds to health advice and other information being shared.
Epidemiological and genetic evidence for the relationship between ABO blood group and human cancer
Authors: Cui Huijie , Qu Yang , Zhang Li , Zhang Wenqiang , Yan Peijing , Yang Chao , Zhang Min , Bai Ye , Tang Mingshuang , Wang Yutong , Chen Lin , Xiao Chenghan , Zou Yanqiu , Liu Yunjie , Zhang Ling , Yang Yanfang , Yao Yuqin , Li Jiayuan , Liu Zhenmi , Yang Chunxia , Jiang Xia , Zhang Ben 
Published: April 2023

AbstractTo comprehensively evaluate the etiological role of ABO blood group in human cancer, we conducted a large‐scale meta‐analysis of 127 publications totaling 20 million participants including 231 737 patients of 20 cancers, supplemented by genetic evidence. Effects of A, AB and B groups on cancer risk were investigated by respectively comparing with O group and their combined counterparts, and subgroup analysis by ethnicity was conducted for O‐referent models. For cancer categories, A group increased risk of cancers of oral cavity and nasopharynx, digestive and female genital organs, while both AB and B groups showed associations with cancers of digestive and female genital organs. For individual cancers, A group significantly increased the risk of nine cancers including oral cavity (OR = 1.17, P = .013), stomach (OR = 1.19, P = 3.90 × 10−15), pancreas (OR = 1.33, P = 9.89 × 10−33), colorectum (OR = 1.09, P = .001), liver (OR = 1.23, P = .011), ovary (OR = 1.13, P = .001), cervix (OR = 1.17, P = .025), bladder (OR = 1.12, P = .025) and breast (OR = 1.06, P = .043). AB group showed associations with only three cancers: stomach (OR = 1.10, P = .007), pancreas (OR = 1.21, P = .001) and ovary (OR = 1.28, P = .006). B group, except for shared associations with A group on pancreas (OR = 1.20, P = 2.27 × 10−5) and cervix cancers (OR = 1.13, P = .011), had two distinct associations with esophagus (OR = 1.17, P = .002) and nonmelanoma skin cancers (OR = 0.96, P = .017). Ethnicity‐specific analyses revealed the notable effects of non‐O groups on pancreatic cancer both in Caucasians and Asians. In genetic analysis, four SNPs were associated with the risk of pancreatic cancer, with rs505922 corresponding to O group showing the strongest protective effect (P = 1.16 × 10−23). Our study provided comprehensive evidence of ABO blood group associated with cancers and highlighted its carcinogenic role.
Multi‐target angiogenesis inhibitor combined with PD‐1 inhibitors may benefit advanced non‐small cell lung cancer patients in late line after failure of EGFR‐TKI therapy
Authors: Yu Lian , Hu Yaohua , Xu Jianlin , Qiao Rong , Zhong Hua , Han Baohui , Xia Jinjing , Zhong Runbo 
Published: April 2023

AbstractTreatments for NSCLC patients with EGFR‐TKI resistance are limited. Given that immunotherapy and antiangiogenic agents may have synergistic antitumor effects, we aimed to analyze the effect of multi‐target angiogenesis inhibitor anlotinib and immune checkpoint inhibitors (ICIs) combination therapy in NSCLC patients who failed EGFR‐TKI. The medical records of lung adenocarcinoma (LUAD) patients with EGFR‐TKI resistance were reviewed. After EGFR‐TKI resistance, patients who simultaneously received anlotinib and ICIs were enrolled in the observation group, and those who received platinum‐pemetrexed chemotherapy were included in the control group. A total of 80 LUAD patients were reviewed and allocated to the anlotinib and ICIs combination therapy (n = 38) and chemotherapy (n = 42) groups. A re‐biopsy was performed in all patients in the observation group before the administration of anlotinib and ICIs. The median follow‐up was 15.63 months (95% CI: 12.19‐19.08). Combination therapy exhibited better PFS (median PFS: 4.33 months [95% CI: 2.62‐6.05] vs 3.60 months [95% CI: 2.48‐4.73], P = .005), and better OS (median OS: 14.17 months [95% CI: 10.17‐18.17] vs 9.00 months [95% CI: 6.92‐11.08], P = .029) than chemotherapy. Most patients (73.7%) received combination therapy as fourth and later lines of therapy, with a median PFS of 4.03 months (95% CI: 2.05‐6.02) and a median OS of 13.80 months (95% CI: 8.25‐19.36). The disease control rate was 92.1%. Four patients discontinued the combination therapy due to adverse events, but the other adverse reactions were manageable and reversible. The combination of anlotinib and PD‐1 inhibitors is a promising regimen for the late‐line treatment of LUAD patients with EGFR‐TKI resistance.
Premature ovarian insufficiency and chance of pregnancy after childhood cancer: A population‐based study (the Fex‐Can study)
Authors: Haavisto Anu , Wettergren Lena , Lampic Claudia , Lähteenmäki Päivi M. , Jahnukainen Kirsi 
Published: April 2023

AbstractEndocrine complications are a common late effect after childhood cancer. Our study assessed the prevalence and predictors of premature ovarian insufficiency (POI) and prospects of pregnancy in young female survivors. This nationwide study combined registry and survey data for female childhood cancer survivors aged 19 to 40 years, identified through the National Quality Registry for Childhood Cancer in Sweden. Of 1989 approached young women, 1333 (67%) participated by completing a survey. Median age at diagnosis 1981 to 2017 was 6 (range 0‐17) and at study 28 (19‐40) years. There were two indicators of POI, induced puberty reported in 5.3% and estrogen replacement therapy (ERT) in 9.3% at assessment. In separate logistic regression analyses (P < .001), induced puberty and ERT were significantly predicted by hematopoietic stem cell transplantation (HSCT), abdominal irradiation, central nervous system irradiation and chemotherapy. ERT was also associated with older age at diagnosis. Of the 626 women (48% of responders) who had tried to become pregnant, 25% had undergone fertility investigations and 72% reported having a biological child. Treatment with HSCT was associated with 5.4 times the odds of needing fertility investigations (P < .001). Having a biological child was associated with non‐HSCT treatment, but also with ever having had a partner and older age at the time of study (all P < .001). In conclusion, the majority of those female childhood cancer survivors who had tried to conceive were able to successfully give birth. However, a small identifiable group of female survivors are at risk of subfertility and early menopause.
Determinants of influenza vaccine uptake among pregnant women: Demographics and medical care access
Authors: Marin Evelyn S. , McCall‐Hosenfeld Jennifer , Weng Xingran , Wang Li 
Published: April 2023

AbstractObjectiveTo investigate how sociodemographic and medical care access variables are associated with influenza vaccine uptake among pregnant women in the USA.MethodsThis is an observational study using 2015–2019 data from the US Behavioral Risk Factor Surveillance System. Pregnant women aged 18–49 years were included. Weighted χ2 tests and weighted logistic regression models were performed using the software SAS.ResultsA total of 9149 pregnant women were included, of whom 39.9% received the influenza vaccine. Age, income, education and race/ethnicity were significantly associated with influenza vaccination. The following medical access factors were associated with a higher likelihood of receiving the influenza vaccine: having insurance (odds ratio [OR] 1.43, 95% confidence interval [CI] 1.04–1.97), having had a checkup in the past year (OR 1.69, 95% CI 1.40–2.03), and having a primary care provider (OR 1.45, 95% CI 1.18–1.78). In subgroup analysis by race/ethnicity, non‐Hispanic black women had the least difference in influenza vaccine uptake between those with medical care access and those without.ConclusionOur findings suggest that the influenza vaccine uptake level was far from optimal among pregnant women. Influenza vaccine uptake was associated with social demographics and medical care access among pregnant women.
Oil prices uncertainty, endogenous regime switching, and inflation anchoring
Authors: Chang Yoosoon , Herrera Ana María , Pesavento Elena 
Published: April 2023

SummaryUsing a novel approach to model regime switching with dynamic feedback and interactions, we extract latent mean and volatility factors in oil price changes. We illustrate how the volatility factor constitutes a useful measure of oil market risk (or oil price uncertainty) for policy makers and analysts as it captures uncertainty not reflected in other economic/financial uncertainty measures. Then, in the context of a VAR, we investigate the role of oil price uncertainty in driving inflation expectations and inflation anchoring. We show that shocks to the mean factor lead to higher expected inflation and inflation disagreement among professional forecasters and households. In contrast, shocks to the volatility factor act as aggregate demand shocks in that they result in lower expected inflation, yet they do increase disagreement about future inflation among professional forecasters and, especially, among households. We also provide econometric evidence suggesting the proposed endogenous volatility switching model can outperform other regime switching models.