bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of Coronary Artery Diffuse Calcification Stenosis by Corrected
Coronary Opacification Difference
Authors: Shen Fangjie , Huang Jingfeng , Ding Qianjiang , Mao Quanliang , Ruan Xinzhong , Pan Yuning 
Published: May 2023

Objectives:
The artifacts produced by calcification on coronary computed tomographic angiography (CCTA) have a great influence on the diagnosis of coronary stenosis. The purpose of this study is to investigate the value of corrected coronary opacification (CCO) difference in the diagnosis of stenosis in diffusely calcified coronary arteries (DCCAs).

Methods:
A total of 84 patients were enrolled. The CCO difference across the diffuse calcification was measured through CCTA. Coronary arteries were grouped according to the extent of stenosis obtained by invasive coronary angiography (ICA). The Kruskal-Wallis H test was used to compare the CCO differences between different groups and a receiver operating characteristic (ROC) curve was used to evaluate the diagnostic efficacy of the CCO difference.

Results:
Among the 84 patients, 58 patients had one DCCA, 14 patients had 2 DCCAs, and 12 patients had 3 DCCAs. A total of 122 coronary arteries were examined, 16 showed no significant stenosis, 42 had <70% stenosis, and 64 had 70-99% stenosis. The median CCO differences among the 3 groups were 0.064, 0.117, and 0.176, respectively. There were significant differences between the group without stenosis and the group with 70-99% stenosis (H = -3.581, P = 0.001), and between the group with <70% stenosis and the group with 70-99% stenosis (H = -2.430, P = 0.045). The area under the ROC curve was 0.681 and the optimal cut-off point was 0.292. Taking the ICA results as the gold standard, the sensitivity and specificity for the diagnosis of ≥70% coronary stenosis with a cut-off point of 0.292 were 84.4% and 44.8%, respectively.

Conclusion:
CCO difference could be useful in the diagnosis of ≥70% severe coronary stenosis in DCCA. Through this non-invasive examination, the CCO difference could be a reference for clinical treatment.
Correlation of Diffusion weighted MR Imaging and ADC Values of Hepatic
Metastasis of Gastrointestinal Stromal and Gastroenteropancreatic
Neuroendocrine Tumors
Authors: Aydın Hasan , Metin Melike Ruşen , Kızılgöz Volkan 
Published: May 2023

Background:
DWI and ADC-mapping was performed to analyze hepatic metastasis of GIST, GEP-NET.

Objective:
The objective of this study is to present hepatic metastasis of GIST and GEP-NET with Diffusion weighted MR imaging(DWI) and the Apparent diffusion coefficients (ADC) values of masses.

Methods:
18 GIST patients and 8 GEP-NET patients were examined retrospectively. 11 males and 6 females were present in GIST group, 7 males to 5 females were involved in GEP-NET group. 18 primary GIST and 10 hepatic metastasis of GIST, 8 original GEP-NET and 19 hepatic metastasis of GEP-NET; total 55 GIST and GEP-NET masses were analysed by ADC mapping. MR images were acquired by 1,5 T MR units (32 mT/min gradient strength- Achieva; Philips Healthcare, Best, Netherlands and 32 channel GE Signa GE-Wisconsin-USA); by using a 4-8 channel standard phased-array torso XL coil, all images were evaluated by an Abdominal MRI experienced radiologist. DWI was performed in the transverse plane by using spin-echo-planar imaging sequence.

Results:
No statistical differences were observed between GIST and GEP-NET patients according to age and gender variations. No significant statistical differences were observed according to the diameters and ADC values of GIST and GEP-NET patients. A significant statistical difference was observed between GIST and GEP-NET groups in terms of size of liver metastasis which was significantly higher in GIST patients. All three groups (GIST_Hep. MET, GEP-NET_Liver_Met and normal) were statistically differed according to ADC values. With the ROC curve analysis: Hepatic metastasis of GIST(n=10) and normal liver (n:47) had cut-off value for ADC: 0.925 under AUC: 0.939 with regard to ADC values and regarded 89.4 % Sensitivity, 100% Specificity, 100% PPV and 66.7% PPV. ROC curve of GEP NET_ Hepatic metastasis (n=19) group and normal liver (n:47) group presented cut-off value for ADC: 0.860 under AUC: 0.967 correlated to ADC values with 93.6 % sensitivity, 89.5% specificity, 95.7% PPV and 85% PPV.

Conclusion:
High cellular tumors resulted from liver metastasis of GIST and GEP-NET’s, and a positive correlation was observed between ADC values and cellularity/differentiation ratios of metastatic masses.
A Light, 3D UNet-based Architecture for Fully Automatic Segmentation of Prostate Lesions from T2-MRI Images
Authors: Bálint Zoltán , Coroama Larisa Gabriela , Diosan Laura , Telecan Teodora , Andras Iulia , Crisan Nicolae , Andreica Anca , Caraiani Cosmin , Lebovici Andrei , Boca Bianca 
Published: May 2023

Introduction:
Prostate magnetic resonance imaging (MRI) has been recently integrated into the pathway of diagnosis of prostate cancer (PCa). However, the lack of an optimal contrast-to-noise ratio hinders automatic recognition of suspicious lesions, thus developing a solution for proper delimitation of the tumour and its separation from the healthy parenchyma, which is of primordial importance.

Method:
As a solution to this unmet medical need, we aimed to develop a decision support system based on artificial intelligence, which automatically segments the prostate and any suspect area from the 3D MRI images.
We assessed retrospective data from all patients diagnosed with PCa by MRI-US fusion prostate biopsy, who underwent prostate MRI in our department due to a clinical or biochemical suspicion of PCa (n=33). All examinations were performed using a 1.5 Tesla MRI scanner. All images were reviewed by two radiologists, who performed manual segmentation of the prostate and all lesions. A total of 145 augmented datasets were generated. The performance of our fully automated end-to-end segmentation model based on a 3D UNet architecture and trained in two learning scenarios (on 14 or 28 patient datasets) was evaluated by two loss functions.

Results:
Our model had an accuracy of over 90% for automatic segmentation of prostate and PCa nodules, as compared to manual segmentation. We have shown low complexity networks, UNet architecture with less than five layers, as feasible and to show good performance for automatic 3D MRI image segmentation. A larger training dataset could further improve the results.

Conclusion:
Therefore, herein, we propose a less complex network, a slim 3D UNet with superior performance, being faster than the original five-layer UNet architecture.
A New Buffer for Gallium-68 Labeling Suitable for use in Nuclear Medicine;
Triethanolamine (TEA)
Authors: Uğur Ayşe , Yaylali Olga , Yüksel Doğangün 
Published: May 2023

Background:
Radiopharmaceuticals labeled with [68Ga] from positron emission tomography
(PET) radionuclides are utilized in nuclear medicine for non-invasive in vivo molecular imaging.
Buffer solutions for radiolabeling play an important role as choosing the right buffer for the
reaction helps to obtain high yield radiopharmaceuticals. Zwitterionic organic buffer 4-(2-
hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), sodium acetate (CH3COONa), sodium
bicarbonate (NaHCO3) buffers are widely used for labeling of peptides with [68Ga]Cl3. They can
be used for peptide labelings with the acidic [68Ga]Cl3 precursor of triethanolammonium (TEA)
buffer. The cost and toxicity of TAE buffer are relatively low.

Method:
For [68Ga]GaPSMA-HBED-CC and [68Ga]GaDOTA-TATE labeling, the effectiveness of
TEA buffer without chemical impurities in radiolabeling reactions and QC parameters in successful
labeling was investigated.

Results:
The method used to label [68Ga]Cl3 with PSMA-HBED-CC peptide in the presence of
TEA buffer was successful when applied at room temperature. High purity radiosynthesis suitable
for clinical use was performed to obtain DOTA-TATE peptide with the addition of 363K temperature
and radical scavenger. Quality control tests with R-HPLC have shown that this method is
suitable for clinical use.

Conclusion:
We present an alternative procedure for labeling PSMA-HBED-CC and DOTATATE
peptides with [68GaCl3] to obtain high radioactive doses of final radiopharmaceutical products
used in nuclear medicine clinical applications. We have provided a quality-controlled final
product that can be used in clinical diagnostic procedures. With the use of an alternative buffer,
these methods could be adapted to semi-automatic or automated modules routinely used in nuclear
medicine laboratories to label [68Ga]-based radiopharmaceuticals.
Penerapan Strategi Pembelajaran Reciprocal Learning untuk Meningkatkan Hasil Belajar Siswa di SMA Negeri 1 Pancur Batu
Authors: Sari Jeneri Puspita , Halimatussya’diyah Halimatussya’diyah , Intanna Sauda Julia , Nurbaya Siti , Tanjung Indayana Febriani 
Published: May 2023

This research is a classroom action research conducted in two cycles. Each cycle consists of planning, implementation, observation and observation. The subjects of this study were students of class X MIA SMA Negeri 1 Pancur Batu Academic year 2021 / 2022. This study aims to determine the improvement in learning outcomes of class X MIA students in Biology subjects through learning strategies (Reciprocal Learning). The instruments used are observation, pretest and posttest. Student observation sheet The indicator of the success of this study is seen from the mastery of student learning who achieves the Minimum Completeness Criteria (KKM) of 80. From the results of the study, in the first cycle the student learning completeness achieved is 75%, and the second cycle is 85%, where the increase the percentage of student learning outcomes from cycle I to cycle II reached 10%. Based on the results of this study, it can be concluded that student learning outcomes in Biology can be increased through Reciprocal Learning learning strategies, and have the advantage of developing student knowledge, forming collaboration between students and creating student curiosity, especially in the environment around the school at SMA Negeri 1 Pancur Batu.
Key words: Classroom Action Research, student learning outcomes, Reciprocal Learning Model

ABSTRAK
Eksplorasi ini merupakan penelitian kegiatan hasil studi yang diarahkan dalam dua siklus. Setiap siklus terdiri dari penyusunan, pelaksanaan, persepsi dan persepsi. Subyek review ini adalah siswa kelas X MIA SMA Negeri 1 Pancur Batu tahun ajaran 2021/2022. Review ini berencana untuk memutuskan peningkatan hasil belajar siswa kelas X MIA pada mata pelajaran Biologi melalui teknik pembelajaran (Reciprocal Learning). Instrumen yang digunakan adalah persepsi, pretest dan postest. Lembar persepsi siswa kemajuan penelitian ini dilihat dari kewenangan pencapaian siswa yang mencapai Kriteria Ketuntasan Minimal (KKM) 80. Dari hasil review, pada siklus utama pemenuhan pembelajaran siswa yang dicapai adalah 75%. , dan siklus II sebesar 85%, dimana laju pemuaian pada siswa yang memperoleh hasil dari siklus I ke siklus II mencapai 10%.
Kata kunci: Penelitian Tindakan Kelas, hasil belajar siswa, Model Pembelajaran Reciprocal
Penerapan Strategi Pembelajaran Kooperatif Tipe NHT Untuk Meningkatkan Hasil Belajar Siswa Dikelas XI SMA Hang Tuah Belawan
Authors: Pasaribu Yuswitari , Tanjung Indayana Febriani , Sudarmaji Asahy Syadza , Ayu Annisa , Athiyah Sarah Ummi 
Published: May 2023

Learning results are a portrayal of how understudies grasp the material presented by the educator. Learning results are output values as numbers or letters that understudies get in the wake of getting learning material through a test or test given by the educator. From the learning results, the educator can get data on how far understudies comprehend the material being considered. The objectives of this study hall activity research are, first, to fulfill the tasks of the Classroom Action Research Course. second, to research and implement NHT type cooperative learning strategies in improving understudy learning results. This examination was led at the HANG TUAH BELAWAN SMA school, with the research subjects namely the Principal, Teachers and Students as many as 72 people consisting of 37 men and 35 women, and using 2 classrooms. The sort of exploration use. In this classroom action research, it consists of 2 cycles, 1 cyclec on sists of 2 meetings, if there are 2 cycles, it means that it consists of 4 meetings. Each cycle comprises of 4 phases, specifically: Planning, Action Implementation, Observation, furthermore, Reflection. The instruments utilized in this study were interviews, perceptions, filling in student worksheets, learning out comes tests (pretest and posttest), and documentatio.
Key words: NNT, learning outcomes, students, intruments

ABSTRAK
Hasil belajar merupakan gambaran bagaimana siswa menangkap materi yang disampaikan oleh pendidik. Hasil belajar adalah nilai keluaran berupa angka atau huruf yang diperoleh siswa setelah mendapatkan materi pembelajaran melalui tes atau ulangan yang diberikan oleh pendidik. Dari hasil belajar tersebut, pendidik dapat memperoleh data seberapa jauh pemahaman peserta didik terhadap materi yang sedang dipelajari. Tujuan dari penelitian kegiatan ruang belajar ini adalah, pertama, untuk memenuhi tugas mata kuliah Penelitian Tindakan Kelas. kedua, meneliti dan menerapkan strategi pembelajaran kooperatif tipe NHT dalam meningkatkan hasil belajar siswa. Ujian ini dipimpin di sekolah SMA HANG TUAH BELAWAN, dengan subjek penelitian yaitu Kepala Sekolah, Guru dan Siswa sebanyak 72 orang yang terdiri dari 37 laki-laki dan 35 perempuan, serta menggunakan 2 ruang kelas. Jenis penggunaan eksplorasi. Dalam penelitian tindakan kelas ini terdiri dari 2 siklus, 1 siklus terdiri dari 2 pertemuan, jika ada 2 siklus berarti terdiri dari 4 pertemuan. Setiap siklus terdiri dari 4 tahapan, yaitu: Perencanaan, Pelaksanaan Tindakan, Observasi, selanjutnya Refleksi. Instrumen yang digunakan dalam penelitian ini adalah wawancara, persepsi, pengisian lembar kerja siswa, tes hasil belajar (pretest dan posttest), dan dokumentasi.
Kata kunci: NHT, hasil belajar, peserta didik, instrumen
Pengaruh Penerapan Model Pembelajaran Auditory Intellectually Repetition (AIR) dan Motivasi Terhadap Hasil Belajar Siswa Kelas VIII SMP Negeri 14 Kota Jambi
Authors: Masitah Masitah , Purwaningsih Sri , Siburian Jodion 
Published: May 2023

This study aims to determine the effect of using the Auditory Intellectually Repetition (AIR) learning model and motivation on student learning outcomes. The type of research used was quasi-experimental research with a pretest-posttest control group design not randomly. The type of research design used is a 2x2 factorial design. The population in this study were students of grade VIII junior high school first semester. The samples used were class VIII A and VIII C, the samples were taken by purposive sampling technique. Learning achievement data was measured using a learning achievement test and motivational data was measured using a questionnaire. Data were analyzed using two way ANOVA. The results of the analysis show that the difference in post-test scores for the experimental class is higher than that for the control class. Based on the results of the study, it can be concluded that: 1) There is an effect of using the Auditory Intellectually Repetition (AIR) learning model on students' science learning outcomes. 2) There is a motivational influence on students' science learning outcomes. 3) There is no interaction between the use of the Auditory Intellectually Repetition (AIR) learning model and motivation on student learning outcomes.
Key words: Auditory Intellectually Repetition (AIR) learning model, motivation and learning outcomes

ABSTRAK
Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan model pembelajaran Auditory Intellectually Repetition (AIR) dan motivasi terhadap hasil belajar siswa. Jenis penelitian yang digunakan adalah penelitian eksperimen semu dengan desain penelitian pretest-postest grup kontrol tidak secara random. Jenis rancangan penelitian yang digunakan adalah desain factorial 2x2. Populasi pada penelitian ini adalah siswa kelas VIII SMP semester satu. Sampel yang digunakan adalah kelas VIII A dan VIII C, sampel diambil dengan teknik purposive sampling. Data prestasi belajar diukur dengan menggunakan tes prestasi belajar dan data motivasi diukur dengan menggunakan angket kuesioner. Data di analisis dengan menggunakan ANOVA dua jalur. Hasil analisis menunjukan bahwa selisih nilai post test untuk kelas eksperimen lebih tinggi dibandingkan kelas kontrol. Berdasarkan hasil penelitian maka dapat disimpulkan bahwa: 1) Terdapat pengaruh penggunaan model pembelajaran Auditory Intellectually Repetition (AIR) terhadap hasil belajar IPA siswa. 2) Terdapat pengaruh motivasi terhadap hasil belajar IPA siswa. 3) Tidak terdapat interaksi antara penggunaan model pembelajaran Auditory Intellectually Repetition (AIR) dan motivasi terhadap hasil belajar siswa.
Kata kunci: Model pembelajaran Auditory Intellectually Repetition (AIR), motivasi dan hasil Belajar
Pengaruh Model Pembelajaran Problem Based Learning untuk Meningkatkan Hasil Belajar Siswa Pada Materi Sistem Reproduksi Manusia Di SMAN 10
Authors: Nur Fadilah Anissa , Nabila Syahna Permata Sari Nabila Syahna Permata Sari , Annisa Tanjung Annisa Tanjung , Azzahra Putri Ramadana Azzahra Putri Ramadana , Reni Rahayu Reni Rahayu 
Published: May 2023

The purpose of this review is to investigate the effect of compound fish bone on the conceptual framework of school performance and medical awareness of high school students. In this review, we used a quasi-sectional study design with pre-test and post-test control package models. An example in this review is a low-level study of XI MIPA 1 and XI MIPA 2 by SMA N 10 Kota Medan, which was not fully addressed by the target test method. The information was gathered through exams and admission forms. According to the information survey, students' learning performance could be improved following the completion of the completed learning practice at the level of 79.54% and 90.48% in both classes, it was found that increased awareness of health care. Given the results, the use of the herring-problem model is very likely to affect the academic results and medical prospects of students in secondary schools.
Key words: Problem-based learning, learning outcomes, health care attitude

ABSTRAK
Penelitian ini bertujuan untuk menganalisis pengaruh problem-based fishbone pada sistem reproduksi terhadap hasil belajar dan sikap pemeliharaan kesehatan siswa SMA. Penelitian ini menggunakan desain eksperimen semu dengan desain pretest-posttest control group design. Sampel penelitian ini adalah siswa kelas XI MIPA 1 dan XI MIPA 2 SMA N 10 yang ditentukan dengan teknik purposive sampling. Pengumpulan data dilakukan dengan tes dan lembar observasi. Hasil analisis data menunjukkan bahwa hasil belajar siswa dapat meningkat setelah kegiatan pembelajaran selesai dengan ketuntasan untuk kedua kelas masing-masing sebesar 79,54% dan 90,48%, dan siswa memiliki sikap peduli kesehatan yang baik. Berdasarkan hasil penelitian dapat disimpulkan bahwa penerapan model problem based-fishbone berpengaruh terhadap hasil belajar dan sikap pemeliharaan kesehatan siswa SMA.
Kata kunci: Problem Base Learning, Hasil Belajar, Sikap Perawatan Kesehatan
Balai Pelestarian Cagar Budaya (BPCB) di Pejeng, Gianyar, Bali Sebagai Sumber Belajar Sejarah di SMA
Authors: Rizqi Sholeha Putri Anisya Setia , Maryati Tuty , Arta Ketut Sedana 
Published: May 2023

Penelitian ini bertujuan untuk mengetahui : (1) latar belakang berdirinya Balai Pelestarian Cagar Budaya di Pejeng, Gianyar, Bali, (2) koleksi yang disimpan di Balai Pelestarian Cagar Budaya di Pejeng, Gianyar, Bali yang dapat dijadikan sumber belajar sejarah, dan (3) pemanfaatan Balai Pelestarian Cagar Budaya di Pejeng, Gianyar, Bali sebagai sumber belajar sejarah. Metode penelitian yang digunakan adalah penelitian kualitatif. Meliputi: (1) Rancangan Penelitian, (2) Penentuan Lokasi Penelitian,(3) Penentuan Informan, (4) Pengumpulan Data, (5) Kesahihan Data, (6) Analisis Data. Hasil penelitian menunjukkan bahwa: (1) latar belakang berdirinya Balai Pelestarian Cagar Budaya yang diresmikan pada tahun 1989 telah mengalami perubahan nama sebanyak tujuh kali sesuai dengan kebijakan pemerintah (2) koleksi yang disimpan di Balai Pelestarian Cagar Budaya terdiri dari benda peninggalan pada masa paleolithikum, mesolithikum, neolithikum, megalithikum, perundagian dan hindu-budha (3) Balai Pelestarian Cagar Budaya sejauh ini sudah dimanfaatkan sebagai sumber belajar sejarah baik untuk kalangan pelajar atau mahasiswa. Terkhusus bagi siswa SMA koleksi peninggalan diolah menjadi materi alternatif dengan berpacuan pada merti-materi pokok yang telah termuat pada silabus.
Dari SGKP Hingga SMK Negeri 2 Singaraja (Tinjauan Sejarah dan Potensinya Sebagai Sumber Belajar Sejarah Di SMA)
Authors: Nirmala Gloria , Purnawati Desak Made Oka , Arta Ketut Sedana 
Published: May 2023

Penelitian ini bertujuan untuk mengetahui (1) sejarah dan perkembangan SMK Negeri 2 Singaraja mulai dari SGKP (Sekolah Guru Kepandaian Putri) hingga menjadi SMK Negeri 2 Singaraja, (2) Sistem pendidikan yang berkembang di SMK Negeri 2 Singaraja pada kurikulum dari SGKP sampai SMK Negeri 2 Singaraja. Penelitian ini merupakan penelitian sejarah dengan menggunakan metode penelitian kualitatif dengan langkah-langkah (1) Teknik Pengumpulan Sumber yang dilakukan melalui Observasi, Wawancara, Studi Dokumentasi,(2) Kritik Sumber (Kritik ekstern dan Kritik Intern), (3) Interpretasi (Analisis Data), (4) Hsitoriografi (Penulisan Sejarah). Hasil penelitian menunjukkan bahwa (1) SMK Negeri 2 Singaraja merupakan sekolah yang memiliki perjalanan sejarah yang cukup panjang. Berdirinya cukup strategis. Berdirinya SMK Negeri 2 Singaraja dilatarbelakangi oleh adanya faktor pembangunan. Perkembangan SMK Negeri 2 Singaraja sangat pesat sehingga menjadikannya sekolah mandiri yang awalnya dari SGKP (Sekolah Guru Kepandaian Putri) hingga menjadi SMK Negeri 2 Singaraja.
Kata kunci : Sejarah, Sistem pendidikan, Kurikulum