bluuebunny/crossref_metadata_2025_split huggingface dataset:
The robust feature extraction of audio signal by using VGGish model
Authors: Diwakar Mandar , Gupta Brijendra 
Published: June 2023

Abstract
This research paper explores the use of the VGGish pre-trained model for feature extraction in the context of speech enhancement. The objective is to investigate the effectiveness of VGGish in capturing relevant speech features that can be utilized to enhance speech quality and reduce noise interference. The experimentation is conducted on the MUSAN dataset, and the results demonstrate the capability of the VGGish model in extracting rich and discriminative features encompassing spectral, temporal, and perceptual characteristics of speech. These features are then employed in various speech enhancement techniques to improve speech intelligibility, enhance spectral clarity, and reduce artifacts caused by noise and distortions. Comparative analysis with traditional methods reveals the superior performance of the VGGish model in capturing a comprehensive representation of the speech signal, leading to better discrimination between speech and noise components. The findings highlight the potential of the VGGish model for speech enhancement applications, offering opportunities for improved communication systems, automatic speech recognition, and audio processing in diverse domains. Future research directions include optimizing the VGGish model for specific speech enhancement tasks, exploring novel feature fusion techniques, and integrating other deep learning architectures to further enhance system performance and flexibility. Overall, this research contributes to advancing speech processing and provides a foundation for enhancing speech quality, reducing noise interference, and improving the overall listening experience.
Video Background Music Recommendation Based on Multi-level Fusion Features
Authors: Zhao Xin , Li Xiaobing , Tie Yun , Qi Lin 
Published: June 2023

Abstract
People resonate more with music when exposed to visual information, and music enhances their perception of video content. Cross-modal recommendation techniques can be used to suggest appropriate background music for a given video. However, there is not a simple correspondence between the different modal data. Therefore, to explore the association between the two modalities of video and music, we propose MFF-VBMR, a video background music recommendation model based on multi-level fusion features. The model uses the cross-modal information of static, dynamic and emotional content of video and music to realize the task of matching and recommending suitable background music for a given video. We propose a feature normalized convolutional similarity algorithm network FNC, which takes into account the pairwise similarity of visual and acoustic regions without losing region details. Experimental results show that the proposed model outperforms other existing models in terms of performance and achieves satisfactory results for video background music recommendation.
Synthesis of anion-binding molecules towards novel benzothiazinones
Authors: Süttő-Kaczeus Krisztina , Krajsovszky Gábor , Bogdán Dóra , Gáti Tamás , Szabó Pál , Horváth Péter , Mandity Istvan M. 
Published: June 2023

Abstract
Herein we report the synthesis of a set of novel N-benzoylthioureas, 2-(acyl)amino-4H-3,1-benzothiazin-4-ones and thiourea derivatives with amino acid moieties. The corresponding benzoyl isothiocyanates were synthesised from a variety of substituted benzoyl chlorides with ammonium thiocyanate or from benzoic acids with the trichloroisocyanuric acid/triphenylphosphine (TCCA/TPP) system. The resulting compounds were reacted with substances containing amino groups to give new molecules with thiourea functionalities, which could be potential chloride ion binders.
Computing the Kirchhoff index and the Wiener index of spiro para-hexagonal cylinder chain
Authors: Reja Md Selim , N Sk. Md. Abu 
Published: June 2023

Abstract
Kirchhoff index of a graph is given by the sum of inverses of non-zero Laplacian eigenvalues multiplied with the number of vertices of the graph. It has been studied for several linear and cylinder chains of chemically important graphs, so far. In this paper, we consider the spiro para-hexagonal cylinder chain and find its Kirchhoff index, Wiener index and number of spanning trees. We observe that like many other chain graphs, the ratio of Wiener index and Kirchhoff index approaches to 3 for large graphs belong to this class.
Galileo High Accuracy Service Performance and Anomaly Mitigation Capabilities
Authors: Martini Ilaria , Susi Melania , Cucchi Luca , Fernandez-Hernandez  
Published: June 2023

Abstract
Precise Point Positioning (PPP) and Real Time Kinematic (RTK) techniques are interesting in several sectors, especially for autonomous applications. These users have high accuracy needs coupled with stringent requirements on continuity, availability, integrity, and convergence time, whose satisfaction can be challenging in harsh environments. Galileo launched on January 2023 the initial High Accuracy Service (HAS), a European free-of charge PPP service with a worldwide coverage transmitted on E6 signals and provided through an internet connection. This paper characterizes the Galileo HAS product performance, including orbital errors, clock errors, code biases, and overall Signal In Space Error (SISE), with live signals transmitted since HAS service declaration. The paper also presents the behaviour of HAS SIS in the case of four satellite anomalies between September 2021 and August 2022, occurring for Galileo and GPS. Finally, the paper presents the results of HAS performance in both static open sky and road scenarios, showing a few-decimetre accuracy even in environments with degraded visibility. The paper shows the improvements in terms of robustness to satellite anomaly thanks to the Galileo HAS characteristics.
Stakeholders’ Use and Awareness of the Benefits of Wetland Management Practices in Ewaso Narok Swamp in Kenya
Authors: Mwangi Magdalene Mutumi , Nyikal Rose Adhiambo , Otieno David Jakinda 
Published: June 2023

Abstract
Wetlands are important for their richness in biodiversity and livelihood support functions. Thus, their wise use is advocated in the Ramsar Convention and calls for implementing conservation approaches to maintain the ecological character of such lands. According to this, the factors responsible for degradation, like the indiscriminate use of fertilizers, should be controlled. Wetland management practices (WMPs) are essential and safe substitutes for fertilizers because they promote resource conservation and increase farm yields. Awareness of the benefits of the WMPs is expected to enhance their utilization and reduce the use of fertilizers and chemicals which affect both wetlands and human health. To ascertain the felt needs in Ewaso Narok Swamp, a survey was carried out among two major stakeholder groups: The Water Resource Users Association (WRUA) and Water Resource Authority (WRA). Additionally, a study determined if benefit awareness influenced the use of WMPs. The major findings are low uptake of WMPs and high use of fertilizer and other chemicals. Subsequently, results showed that although over 80 percent of users were aware of the benefits of WMPs, their non-use of WMPs was 23 percent, and over 40 percent utilized fertilizer on their farms within the wetland. Furthermore, an increase in benefit awareness is likely to increase the use of soil and water conservation practices and pasture conservation practices by 27 and 16 percent respectively. Therefore, group membership must be encouraged, while fertilizer use in the wetland area should be substituted with WMPs to promote sustainable wetland management.
Pelargonidin-3,5-diglucoside found in Pomegranate aril acts as a potent HIF-1α inhibitor in in-silico study
Authors: Joshi Esha , Pandya Medha , Balar Shilpa , Saiyed Hiram , Patel Saumya , Rawal Rakesh , Desai Urja 
Published: June 2023

Abstract
Hypoxia-inducible factor 1 alpha (HIF-1α) is a transcription factor that regulates the transcription of over 100 genes involved in erythropoiesis, angiogenesis, autophagy, cell survival, and energy metabolism signalling; it appears to be a potential target in cancer therapy. The aim of this study was to identify natural compounds from Naturally Occurring Plant-based Anti-cancer Compound-Activity-Target (NPACT) database with anticancer potential. Molecular docking of 1574 phytochemicals was carried out using Autodock Vina 1.1.2 using the site-specific docking method and the amino acid residue site was near Asn803 of HIF-1α. The protein-ligand complexes considered for molecular dynamics simulation were HIF1α- Bortezomib (as control), HIF 1α- Pelargonidin-3 ,5-diglucoside and HIF1α- (25S)-5-beta-spirostan-3-beta-ol-3-O-alpha-L-rhamnopyranosyl-(1->2)-[alpha-L-rhamnopyranosyl-(1->4)]-beta-D-glucopyranoside. Furthermore, ADMET evaluation for the best ligands was carried out using the pkCSM ADMET server.
Nonlinear impact-echo test for quantitative evaluation of ASR damage in concrete
Authors: Malone Clayton , Sun Hongbin , Zhu Jinying 
Published: June 2023

Abstract
Nonlinear acoustic methods demonstrate high sensitivity for concrete damage evaluation. Among these methods, nonlinear resonance acoustic methods have been widely used in laboratory tests on small scale test samples. In this study, a nonlinear impact-echo (IE) method was proposed for concrete damage evaluation, in which the IE frequency shift was measured at different impact force levels. The nonlinear IE test is similar to the nonlinear impact resonance acoustic spectroscopy (NIRAS) test in the experimental setup and analysis method. However, the nonlinear IE test excites a local thickness resonance mode of a member instead of the global resonance vibration. Therefore, the analyzed mode is not affected by boundary conditions and can be applied to large concrete structural members. To identify the fundamental IE frequency, multiple impacts at different locations were used. The nonlinear IE method was then validated on seven concrete beam specimens with different levels of alkali-silica reaction (ASR) damage. The nonlinear IE test results demonstrate high sensitivity to concrete damage and allow for quantitative assessment of the damage state of concrete without a baseline measurement.
Rethinking Water Sustainability: Precipitation Changes in the Peruvian Andes in the Face of Climate Change
Authors: Peña Valeria Llactayo , Valdivia Jairo , Yarleque Christian , Callañaupa Stephany , Villalobos-Puma Elver , Guizado David , Alvarado-Lugo Robert 
Published: June 2023

Abstract
In high-altitude regions, such as the Peruvian Andes, understanding the transformation of precipitation types under climate change is critical to the sustainability of water resources and the survival of glaciers. Conventional wisdom has primarily focused on the snow-rain dichotomy, often overlooking the potential importance of graupel and hail. In this study, we offer a fresh perspective on this issue, investigating the distribution and types of precipitation on a tropical glacier in the Central Andes. We utilized data from an optical-laser disdrometer and compact weather station installed at 4709 m ASL, combined with future climate scenarios from the CMIP6 project, to model potential future changes in precipitation, including the often-ignored hydrometeor forms of graupel and hail. Our findings highlight that increasing temperatures could lead to significant reductions in solid-phase precipitation, including graupel and hail, with implications for the mass balance of Andean glaciers. For instance, a 2°C rise might result in less than 10\% of precipitation as solid, transforming the hydrological processes of the region. The two future climate scenarios from the CMIP6 project, SSP2-4.5 and SSP5-8.5, offer a broad perspective on potential climate outcomes that could impact precipitation patterns in the Andes. Our study underscores the need to revisit and expand our understanding of high-altitude precipitation in the face of climate change, paving the way for improved water resource management strategies and sustainable glacier preservation efforts in these fragile ecosystems.
Economic analysis of mode of birth in women with low-lying placenta
Authors: Colciago Elisabetta , Ferrara Pietro , Tessitore Isadora Vaglio , Mantovani Lorenzo Giovanni , Vergani Patrizia , Ornaghi Sara 
Published: June 2023

Abstract
Introduction Alongside health consequences, cesarean delivery (CD) has been associated with increased healthcare resource utilization, including multiple obstetric interventions and their related costs. While there is consensus that CD should be performed in case of placenta previa, the most appropriate mode of birth in women with low-lying placenta is still controversial, due to lack of robust data. The aim of this study was to evaluate the healthcare resource utilization and economic impact on the Italian healthcare system of vaginal birth (VB) and CD in women with a low-lying placenta, from a national healthcare service perspective. Method For this retrospective cohort study, patient-level real-world data were derived from a cohort of women with low-lying placenta confirmed at 28–32 weeks’ gestation during the third trimester scan. Low-lying placenta was diagnosed when the inferior placental edge was within 1 to 20 mm from the internal. A cost minimization analysis (CMA) was conducted to compare VB and CD. Since Diagnosis-Related-Group payment may not reflect the real hospital resources used, a micro-costing analysis (MCA) was performed to provide a more comprehensive evaluation of the economic impact of modes of birth. Results The study included 86 women with low-lying placenta at the third trimester scan, 49 (57%) had a VB and 37 (43%) underwent a CD. The CMA showed an economically marginal difference between VB and CD, especially when considering opportunity costs associated with the time needed to look after women. However, the MCA identified charges for each VB being about half of those for each CD. Conclusion The use of patient-level real-world data made it possible to generate basic information to assess the value of available interventions in case of low-lying placenta. A VB should be promoted as a safe option to women with low-lying placenta, avoiding further burden on the healthcare system’s limited resources.
Missense mutation (Ser 654 Leu) in ITGA8 gene leads to renal hypodysplasia: A Case Report
Authors: Singh Kumar Gautam , Moorthy Anbalagan 
Published: June 2023

Abstract
Renal hypodysplasia is a congenital anomaly of the kidney that occurs when part of a kidney does not fully develop in the womb. A lot of genes have been when mutated, results in renal dysplasia. This has encouraged us to search for additional genes and gene variants that may be linked to renal anomalies. Using next-generation sequencing combined with Sanger sequencing, we correlated a variant of the ITGA8 gene (NM_003638.2:c.1961C > T; p.Ser654Leu) to renal hypodysplasia. Detailed studies on this variant revealed that Ser 654 is conserved across different species and the mutation is present in the extracellular domain of the proteins, which has an important role in ligand binding and other protein-protein interactions. For the first time, we present the clinical correlation of ITGA8 gene variant (Ser654Leu) to renal dysplasia.
An in-depth Analysis of Pruritus: Insights from Dermoscopy
Authors: Akca Hanife Merve , Metin Zuhal 
Published: June 2023

Abstract
A dermoscope is a non-invasive diagnostic tool used to visualise subtle clinical patterns of skin lesions and subsurface skin structures not visible to the naked eye. Several dermoscopic patterns exhibit consistent associations with specific diseases, serving as valuable diagnostic indicators to differentiate primary and secondary skin lesions. We evaluated the dermoscopic patterns associated with pruritus and compared these patterns based on specific diagnoses. We performed dermoscopy on skin lesions in 299 patients who presented with itching at the outpatient dermatology clinics of Karaman Training and Research Hospital between June 2022 and August 2022. We documented various dermoscopic findings, such as red globules, purple globules, fabric fiber, white scale, comedone-like openings, follicular plugs,brown dots andpigment network, glomerular vessels, delta signs, and yellow crusts. The study included 299 patients ages 17–89 (mean age: 47.53 ± 17.67) years. Among these patients, 60.2% were females and 39.8% were males. Cutaneous xerosis was observed in 35.8% of the patients, scabies in 19.1%, Prurigo nodularis and atopic dermatitis in 11%, lichen simplex chronicus in 7.7%, pityriasis lichenoides chronica and pityriasis rosea in 2.3% and senile pruritus in 1.7%. The most commonly observed dermoscopic signs included irregular white scales (30.8%), red globules (20.1%), an erythematous background (16.4%), the delta sign (9.4%), nonspecific signs (8.7%), hemorrhagic crust (8%) and arborizing vessels (7.7%). Compared to all other age groups, the incidence of delta signs was significantly higher in patients aged < 20 years (31.6%), whereas the incidence of brown spots was significantly higher in patients aged 30–39 years. Dermoscopy is crucial in the identification of the differential diagnoses of pruritus, a commonly encountered condition in dermatological practice.
Improve the management of cancer-related cognitive impairment in clinical settings: a European Delphi study
Authors: Duivon Mylène , Lange Marie , Binarelli Giulia , Lefel Johan , Hardy-Léger Isabelle , Kiasuwa-Mbengi Régine , Méric Jean-Baptiste , Charles Cécile , Joly Florence 
Published: June 2023

Abstract
Purpose
Cancer-related cognitive impairment (CRCI) is under-addressed by healthcare professionals owing to a lack of clinical management guidelines. This European Delphi study aims to propose recommendations to healthcare professionals for the management of CRCI in patients with non-central nervous system (non-CNS) cancers.
Methods
The survey included European professionals (psychologists, physicians, researchers) who are experts in CRCI. Twenty-two recommendations were developed based on a literature review and authors’ clinical experience, split into three categories: screening, cognitive assessment, intervention. The Delphi method was used. Experts assessed the clinical relevancy of recommendations on a 9-point Likert scale in three rounds. A recommendation was accepted if all votes were between 7 and 9.
Results
Eighteen professionals voted and accepted 15 recommendations. Experts recommended the systematic screening of CRCI, followed by a short objective cognitive assessment, if complaints screened. A comprehensive evaluation is recommended if CRCI persists 6-months post-treatment. Cognitive rehabilitation, physical activity, meditative-movement therapy, and multimodal intervention should be offered. No consensus was reached for frequency and duration of interventions, the professional to administer cognitive rehabilitation and the use of meditation and cognitive training without psychoeducation.
Conclusions
This survey provides 15 recommendations to assist healthcare professionals in detecting, assessing and offering interventions for CRCI to patients with non-CNS cancers.
Implications for Cancer Survivors
These recommendations should be included in supportive care to help healthcare professionals to detect CRCI and thus to propose the best available intervention for patients with cognitive complaints. Developing CRCI management in clinical settings would improve patients’ quality of life.
Outcomes of ovarian-sparing surgery in children with ovarian neoplasm: A meta-analysis and meta-regression
Authors: Lin Hao , Jiang Hongyu , Zhao Shuai , Xia Xuehong , Liu Ziyu , Yang Hong , Li Miaomiao , Jin Mingjun , Tian Qi , Dong Liang , Cui Hualei 
Published: June 2023

Abstract
Objectives.
Ovarian-sparing surgery (OSS) is increasingly used to treat various ovarian neoplasms (ON) in children. The feasibility and prognosis of OSS on ON are still being explored. The aim of this research was to demonstrate the clinical results of implementing OSS in children diagnosed with ON.
Methods.
A thorough search was conducted on PubMed, Cochrane Library, and Embase databases to identify relevant articles. The study calculated the recurrence rate, incidence of benign cases and OSS, along with a 95% confidence interval (CI).
Results.
The study included a total of 14 relevant studies involving 1577 patients. The recurrence rate of ON was 2.0% (95% CI: 1.0%-3.1%), the benign rate was 85.5% (95% CI: 81.5%-89.4%), and the rate of OSS was 60.0% (95% CI: 54.3%-65.6%), the rate of OSS in benign tumors was 497.1% (95% CI: 95.4%-98.8%). As for the distribution of ON: 647 cases (41.2%) of non-neoplastic cysts, 580 cases (36.9%) of germ cell tumors, 279 cases (17.7%) of epithelial tumors, and 61 cases (3.9%) of Sex cord-stromal tumor.
Conclusions.
The results of this meta-analysis suggest that the majority of ON in children is benign and has a meager tumor recurrence rate. TSS should be provided to children with benign lesions to ensure future hormone secretion and reproductive function.
Environmental House Calls Can Reduce Symptoms of Chemical Intolerance: A Demonstration of Personalized Exposure Medicine
Authors: Perales Roger , Rincon Rudy , Forster Jackie V. , Palmer Raymond F. , Hernandez Jessica F. , Bayles Bryan , Grimes Carl , Jaén Carlos R. , Miller Claudia S. 
Published: June 2023

Abstract
Aim The goal of this investigation was to 1) identify exposure sources in the home, 2) teach occupants how to remove or replace them, and 3) determine whether measured levels and reported symptoms could be reduced by these changes.Background Chemical intolerance (CI) is an international public health and clinical concern, but few resources are available to address patients’ often disabling symptoms. Numerous studies show that levels of indoor air pollutants can be two-to-five (or more) times higher than outdoor levels. Fragranced consumer products, including cleaning supplies, air fresheners, and personal care products are symptom triggers commonly reported by susceptible individuals.Methods A team of professionals trained and led by a physician/industrial hygienist and two certified indoor air quality specialists conducted a series of five structured Environmental House Calls (EHCs) in 37 homes of patients reporting chemical intolerances.Results We report three case studies demonstrating that an appropriately structured home intervention can teach occupants how to reduce indoor air exposures and associated symptoms. Symptom improvement, documented using the QEESI Symptom Star, corresponded with reduction of indoor air volatile organic compounds, most notably fragrances.Discussion We address the long-standing dilemma that worldwide reports of fragrance sensitivity have not previously been confirmed by human or animal challenge studies. Our ancient immune systems’ “first responders,” mast cells, which evolved 500 million years ago, can be sensitized by synthetic organic chemicals whose production and use has grown exponentially since WWII. We propose that these chemicals, which include now-ubiquitous fragrances, trigger mast cell degranulation and inflammatory mediator release in the olfactory-limbic tract, thus altering cerebral blood flow and impairing mood, memory, and concentration (so-called “brain fog”). The time has come to translate these research findings into clinical and public health practice.