bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effects of temperature on elastic energy storage and release in a system with a dynamic mechanical advantage latch
Authors: Mendoza Elizabeth , Martinez Maya , Olberding Jeffrey P. , Azizi Emanuel 
Published: September 2023

ABSTRACT
Changes in temperature alter muscle kinetics and in turn affect whole-organism performance. Some organisms use the elastic recoil of biological springs, structures which are far less temperature sensitive, to power thermally robust movements. For jumping frogs, the use of elastic energy in tendons is facilitated through a geometric latching mechanism that operates through dynamic changes in the mechanical advantage (MA) of the hindlimb. Despite the well-documented use of elastic energy storage, frog jumping is a locomotor behavior that is significantly affected by changes in temperature. Here, we used an in vitro muscle preparation interacting in real time with an in silico model of a legged jumper to understand how changes in temperature affect the flow of energy in a system using a MA latch. We used the plantaris longus muscle–tendon unit (MTU) to power a virtual limb with changing MA and a mass being accelerated through a real-time feedback controller. We quantified the amount of energy stored in and recovered from elastic structures and the additional contribution of direct muscle work after unlatching. We found that temperature altered the duration of the energy loading and recovery phase of the in vitro/in silico experiments. We found that the early phase of loading was insensitive to changes in temperature. However, an increase in temperature did increase the rate of force development, which in turn allowed for increased energy storage in the second phase of loading. We also found that the contribution of direct muscle work after unlatching was substantial and increased significantly with temperature. Our results show that the thermal robustness achieved by an elastic mechanism depends strongly on the nature of the latch that mediates energy flow, and that the relative contribution of elastic and direct muscle energy likely shapes the thermal sensitivity of locomotor systems.
Relationship between TV Watching during Childhood and Adolescence, and Artery Function in Adulthood
Authors: HAYNES ANDREW , MCVEIGH JOANNE , HISSEN SARAH L. , LESTER LEANNE , EASTWOOD PETER R. , STRAKER LEON , MORI TREVOR A. , BEILIN LAWRENCE , CARSON JENNIE , GREEN DANIEL J. 
Published: September 2023

ABSTRACT

Purpose
Artery dysfunction is an early, integral stage in atherogenesis that predicts future cardiovascular events. Sedentary behavior, such as TV watching, is highly prevalent and associated with increased risk of developing cardiovascular diseases. This study investigated whether patterns of TV watching throughout childhood and adolescence were associated with artery function in adulthood.

Methods
TV watching data were collected when participants of the Raine Study were aged 5, 8, 10, 14, 17, and 20 yr. Previous latent class analysis indicated three trajectory groups of TV watching: low TV (<14 h·wk−1), high TV (>14 h·wk−1), and increasing TV (change from low TV to high TV). At age 28 yr, participants were invited to undergo tests of brachial and femoral artery function by flow-mediated dilation (FMD). General linear models examined differences in artery function between TV trajectory groups for men and women.

Results
Five hundred sixty participants (n = 261 women, n = 299 men) were included in the study. In women, the low TV group had significantly greater femoral artery FMD (10.8 ± 1.6%) than both High TV (9.0 ± 1.3%, P = 0.005) and Increasing TV groups (8.5 ± 1.3%, P < 0.001); these results were maintained following mediation analysis, including contemporaneous risk factors. There were no significant differences in femoral artery FMD between TV trajectory groups in men (P = 0.955).

Conclusions
This study suggests that TV watching behaviors during childhood and adolescence may have legacy impacts on artery function at age 28 yr, particularly in women. This may increase the risk of atherosclerotic vascular pathologies in later life.
Development and thermophysical analysis of binary eutectics phase change materials for solar drying application
Authors: Pandey Saurabh , Anand Abhishek , Buddhi Dharam , Sharma Atul 
Published: September 2023

Background: In the past 30–40 years, conflicts over limited conventional energy sources and the negative climate change caused by them have attracted researchers and analysts to new, clean, and green energy technologies. Thereby reducing the consumption of conventional fuel and the negative impact on the climate. The production of alternative energy in the form of thermal energy storage using phase change materials (PCMs) is one of the techniques that not only reduces the gap between the supply and demand of energy but also increases the stability of the energy supply. The tendency of PCMs to melt and solidify over a wide temperature range makes them more attractive for use in many applications. The effective and efficient storage of solar energy by PCM has the potential to significantly advance the use of renewable energy. Methods: Organic non-paraffin compound beeswax (BW) mixed with other non-paraffin compounds stearic acid (SA), Palmitic acid (PA), Myristic acid (MA), and Lauric acid (LA) in different compositions with the help of magnetic stirrer at 50–60°C for 3–4 hours to prepare BWSA, BWPA, BWMA, and BWLA eutectic PCM. Results: Prepared eutectics melt and solidify in the temperature range 36–56°C and with latent heat in the range of 155–211 kJ/Kg. Conclusions: Due to suitable temperature and good latent heat storage range, it is a good choice as thermal energy storage, for solar drying applications.
Diversity of functional edaphic macrofauna in Musa acuminata x Musa balbisiana (AAB) agroecosystems
Authors: Zúniga-Gonzalez C. A. , Caballero-Hernández A. J. 
Published: September 2023

Background: This study focused on evaluating the diversity and richness of the edaphic macrofauna in eight banana farms in the western zone of Nicaragua. Methods: The sampling design was random and descriptive, it was divided into two phases, the first was the collection of the sample, and the second was the classification, coding, and storage of the extracted macrofauna populations. Subsequently, the indices of diversity and species richness, relative abundance, by functional groups were estimated. Results: The results showed that the relative abundance of biodiversity was higher in the 0–20 cm soil depth stratum than in the branch and leaf biomass strata. The values ​​of the diversity indices of Dominion, Simpson, Shanon, Margalef, and Equity were in the normal range, with a tendency towards low diversity. Likewise, in the richness of species, the Dominant or most abundant genus were earthworms (Oligochaeta) and Hymenoptera (Solenopsis, Leptothorax, Camponotus, Pheidole), indicating the directly proportional relationship, that is to say, that the greater the number of earthworms the production increases and the greater the number of Hymenoptera it decreases, confirmed with the Pearson correlation coefficient with a reliability of 95%. Conclusions: It was concluded that based on the estimates of the diversity indicators, two detritivore genus (earthworms and Hymenoptera) were the ones with the greatest presence, being important in the production of the banana agrosystem due to the decomposition of organic matter and its nutritional contribution to the plant. We observed a direct correlation with earthworms and an indirect relationship with Hymenoptera.
Editorial practices, perceived quality, and expedient scholarly publishing in a developing nation: a mixed methods study
Authors: Bredan Amin , Tashani Osama , Bakoush Omran 
Published: September 2023

Background: Scholarly literature from the developing world is low and the scientific impact in some countries, including Libya, is much lower compared with their peers. This study explores the editorial practices and editors’ perspectives to gain insight into the standard of scholarly publishing in Libya. Methods: Between 21st January and 12th February, 2022, the editors-in-chief (EC) of Libyan academic journals were invited to complete a questionnaire on editorial practices, degree of satisfaction with submitted and published manuscripts, review processes, and journal performance, as well as challenges facing the journals. Journal websites were examined for quality, and indexation coverage and citations were assessed. We examined the number of citations in Google Scholar for all 2019 articles published in each journal. Descriptive statistics were used to quantitatively summarize the data and thematic analysis was used for the narrative text. Results: 48 ECs completed the questionnaire. The EC was affiliated with the institution that owns the journal in 92% of cases. Most EC (83%) were satisfied with the peer-review quality, 69% believed that most of their published papers add new ideas or findings, and 96% were satisfied with their journal performance. However, despite the high degree of satisfaction, only one journal was indexed in Web of Science or Scopus and only 17% of the journals were indexed in Google Scholar. A qualitative assessment of journal websites revealed shortcomings in publishing practices in a large proportion of the journals. Conclusions: The discordance between the satisfaction of the journal editors and the journal quality indicators points to a break in the quality system of Libyan academic publishing. Similar expedient publishing practices might exist in other countries as well. A comprehensive action plan led by academic institutions to enforce high standards for scholarly publishing is needed to advance research and high-quality scholarly publications in developing countries.
Mapping the theories, content, and outcomes of family-based interventions for children and young people with gaming disorder: A scoping review protocol
Authors: V S Harshini , Abraham Mariam , Prabhu Samyuktha , Shi Jing , Dsouza Deena Dimple 
Published: September 2023

Background: Despite the growth of gaming disorders globally, evidence of the formal involvement of family in treating gaming disorders is limited. When children are affected by gaming disorder, the family may encounter challenges in managing the behavior and in the lack of information regarding the gaming disorder, resulting in inconsistent parenting, which may further exacerbate the problem. Thus, it is essential to involve the family in formal interventions. The current scoping review plans to identify the theories, content, and outcomes of family-based interventions for children and young people with gaming disorders. Methods: This scoping review will follow the Joanna Briggs Institute (JBI) methodology. The population, Concept, and Context (PCC) were used to develop the review question. The studies published in the indexed databases will be searched systematically, and the reference list of included full texts will be searched for relevant studies. Intervention studies published in English from January 2010 to December 2022 will be included. Two independent reviewers will screen the studies against eligibility criteria. The data will be extracted and presented in a tabular and narrative style. Discussion: This scoping review will help better understand content, outcomes, and theories underpinning family-based interventions for children and young people with gaming disorders. Findings will inform the stakeholders about the current topic and guide the potential research areas. Registration details: The protocol has been registered in Open Science Framework with the DOI: https://doi.org/10.17605/OSF.IO/TXWBH
Examining the relationships between contraception and fertility rate in Ghana: Evidence from the 1988 to 2014 Ghana Demographic and Health Surveys
Authors: Gbagbo Fred Y. , Ameyaw Edward K. 
Published: September 2023

Background: There have been some discrepancies between Contraceptive Prevalence Rate (CPR) and Total Fertility Rate (TFR) in Ghana over the years which we examined in this study. Methods: We adopted a repeated cross-sectional study design to examine the relationship between Ghana's CPR and TFR using data from 1988 to 2014 Ghana Demographic and Health Surveys (GDHS). Results: Our findings show that TFR declined from 6.4 to 4.2 births per woman between 1988 and 2014. Bivariate models fitted revealed that between 1988 and 2014, women using contraceptives had higher prospects of bearing more children than women not using contraceptives. This manifested in 1988 (IRR=1.16, 95% CI=1.11, 1.22) and 2014 (IRR=1.20, 95% CI=1.12, 1.29). The multivariable Poisson regression models also showed the same patterns in all the surveys including the 1988 GDHS (IRR=1.12, 95% CI=1.09,1.19) and 2014 (1RR=1.13,95% CI=1.09,1.17). Contrary to earlier studies reports, and common perceptions held by stakeholders in family planning that there is an inverse relationship between CPR and TFR in Ghana, we did not find any such inverse relationship between CPR and TFR in Ghana during the period under review. Conclusions: Based on our findings we believe, contraception alone does not guarantee low fertility in Ghana, hence we recommend a qualitative study to further investigate the plausible factors behind our results/observations from this current study to inform policy and program decisions.
Diagnostic accuracy of 18F Prostate Specific Membrane Antigen (PSMA) PET-CT radiotracers in staging and restaging of high-risk prostate cancer patients and patients with biochemical recurrence: protocol for an overview of reviews
Authors: Dullea Andrew , O'Sullivan Lydia , Carrigan Marie , Ahern Susan , McGarry Maeve , O'Brien Kirsty , Harrington Patricia , Walsh Kieran A. , Smith Susan M. , Ryan Máirín 
Published: September 2023

Background: Correct staging and risk stratification is essential in ensuring prostate cancer patients are offered the most appropriate treatment. Interest has been growing in the use of radiotracers targeting prostate specific membrane antigen (PSMA), including the use of 18F-PSMA PET-CT, as part of the primary staging or restaging of prostate cancer. Preliminary scoping identified a number of relevant systematic reviews and meta-analyses; however, individually, these each appear to look at only part of the picture. An overview of reviews aims to systematically identify, appraise and synthesise multiple systematic reviews, related to a relevant research question or questions. We present a protocol for an overview of reviews, which aims to collate existing evidence syntheses exploring the diagnostic accuracy of 18F-PSMA in staging and restaging of prostate cancer. It also aims to highlight evidence gaps in prostate cancer staging or restaging. Methods: This protocol is reported in line with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for systematic review protocols (PRISMA-P). The search strategy will be designed in consultation with a librarian. Searches will be performed in Medline (EBSCO), Embase (Ovid), Google Scholar and the Cochrane Database for Systematic Reviews, supplemented by a targeted grey literature search, forward citation searching and searching reference lists of included reviews. No language or date restrictions will be applied to the eligibility criteria or the search strategy. Title & abstract and full text screening will be performed independently by two reviewers. Data will be extracted by one reviewer and checked in full by a second reviewer. Quality appraisal will be performed using the Risk of Bias in Systematic Reviews (ROBIS) tool independently by two reviewers, and results will be narratively synthesised. Conclusions: This overview of reviews may be of interest to healthcare professionals, academics and health policy decision-makers. Registration: OSF (September 7, 2023).
ELSMOR – towards European Licensing of Small Modular Reactors: Methodology recommendations for light-water small modular reactors safety assessment
Authors: Lansou Sylvain , Ammirabile Luca , Bakouta Nikolai , Bittan Jeremy , Buchholz Sebastian , Brandelet Jean-Yves , Courtin Etienne , Davelaar Frans , Dombrovsky Stanislav , Droin Jean-Baptiste , Ehster-Vignoud Sophie , Hamama Houda , Helminen Atte , Hollands Thorsten , Iskra Andriy , Israel Sebastien , Lorenzi Stefano , Lovasz Liviusz , Paulus Valerie , Pichancourt Isabelle , Miss Joachim , Nguyen Thuy , Rantakaulio Antti , Rocchi Federico , de-la-Rosa-Blul Juan-Carlos , Ricotti Marco , Seubert Armin , Sevbo Oleksandr , Sholomitsky Stanislav , Suurnäkki Olli , Szogradi Marton , Tulkki Ville , Wielenberg Andreas 
Published: September 2023

Decarbonization of energy production is key in today’s societies and nuclear energy holds an essential place in this prospect. Besides heavy-duty electricity production, other industrial and communal needs could be served by integrating novel nuclear energy production systems, among which are low-power nuclear devices, like small modular reactors (SMRs). The ELSMOR (towards European Licensing of Small Modular Reactors) European project addresses this topic as an answer to the Horizon 2020 Euratom NFRP-2018-3 call. The consortium includes 15 partners from eight European countries, involving research institutes, major European nuclear companies and technical support organizations. The 3.5-year project, launched in September 2019, investigates selected safety features of light-water (LW) SMRs with focus on licensing aspects. Providing a comprehensive compliance framework that regulators can adopt and operate, the licensing process of such SMRs could be optimized, helping their deployment. In this prospect, as a result of ELSMOR’s work, this article gives an overview of the specific issues that LW-SMRs may bring about in the different domains of nuclear safety, in terms of: Methodological standpoints: safety goals, safety requirements, safety principles (defence-in-depth implementation);Main safety functions of reactivity control, decay heat removal and confinement management;Severe accident management;Other safety issues particular to SMRs: use of shared systems; performing of multi-unit probabilistic safety assessment (PSA); refuelling, spent fuel management, transport and disposal management. In this article, adequate methodologies are developed to deal with these issues and to help assess the safety of LW-SMRs. This work gives a precious synthesis of the safety assessment issues of LW-SMRs and of the associated methodologies developed in the context of the ELSMOR European project.
Dynamic Development Contests
Authors: Khorasani Sina , Körpeoğlu Ersin , Krishnan Vish V. 
Published: September 2023

How to Optimally Design Contests in Development Settings for Rapid and Efficient Results: Firms increasingly leverage their expert suppliers to develop innovative products and services while minimizing both time-to-market and expenses. In “Dynamic Development Contests,” Sina Khorasani, Ersin Korpeoglu, and Vish Krishnan study how companies can effectively organize contests to stimulate development efforts from competing suppliers to minimize project lead times while keeping the cost of incentives in check. Their characterization of the optimal designs reveals that flexible rewards are most effective when funds are sufficient. However, in cases where resources are constrained, strategic information disclosure in the form of probabilistic disclosure of any change in the state of competition serves as a valuable incentive instrument that helps contest organizers achieve their lead-time minimization objectives.
A pan-cancer analysis reveals the diagnostic and prognostic role of CDCA2 in low-grade glioma
Authors: Li Wenle , Lv Dong , Yao Jieqin , Chen Boxian , Liu Huanqiang , Li Wensheng , Xu Chengjie , Li Zhenzhe 
Published: September 2023

Background
Cell division cycle associated 2 (CDCA2), a member of the cell division cycle associated proteins (CDCA) family, is crucial in the regulation of cell mitosis and DNA repair. CDCA2 was extensively examined in our work to determine its role in a wide range of cancers.

Methods
CDCA2 differential expression was studied in pan-cancer and in diverse molecular and immunological subgroups in this research. Additionally, the diagnostic and prognostic significance of CDCA2 in pan-cancer was also evaluated using receiver operating characteristic (ROC) and Kaplan–Meier (KM) curves. Prognostic value of CDCA2 in distinct clinical subgroups of lower grade glioma (LGG) was also investigated and a nomogram was constructed. Lastly, potential mechanisms of action of CDCA2 were interrogated including biological functions, ceRNA networks, m6A modification and immune infiltration.

Results
CDCA2 is shown to be differentially expressed in a wide variety of cancers. Tumors are diagnosed and forecasted with a high degree of accuracy by CDCA2, and the quantity of expression CDCA2 is linked to the prognosis of many cancers. Additionally, the expression level of CDCA2 in various subgroups of LGG is also closely related to prognosis. The results of enrichment analyses reveal that CDCA2 is predominantly enriched in the cell cycle, mitosis, and DNA replication. Subsequently, hsa-miR-105-5p is predicted to target CDCA2. In addition, 4 lncRNAs were identified that may inhibit the hsa-miR-105-5p/CDCA2 axis in LGG. Meanwhile, CDCA2 expression is shown to be associated to m6A-related genes and levels of immune cell infiltration in LGG.

Conclusion
CDCA2 can serve as a novel biomarker for the diagnosis and prognosis in pan-cancer, especially in LGG. For the development of novel targeted therapies in LGG, it may be a potential molecular target. However, to be sure, we’ll need to do additional biological experiments to back up our results from bioinformatic predictions.
Global risk factor analysis of myopia onset in children: A systematic review and meta-analysis
Authors: Yu Mingkun , Hu Yuanyuan , Han Mei , Song Jiawei , Wu Ziyun , Xu Zihang , Liu Yi , Shao Zhen , Liu Guoyong , Yang Zhipeng , Bi Hongsheng 
Published: September 2023

Introduction
This work aimed to comprehensively assess the risk factors affecting myopia in children to develop more effective prevention and treatment strategies. To this end, data from database were employed to assess the relationship between the incidence of myopia and its risk factors.

Methods
We searched eight databases online in June 2022. Cohort studies were included that measured the connection between risk factors and myopia. Eligibility was not restricted by language. The Newcastle–Ottawa Scale (NOS) was used to measure the risk of bias and conducted GRADE evaluation to determine the certainty of evidence. Potential risk factors with positive or negative results were seen. Inplasy Registration: https://inplasy.com/inplasy-2022-4-0109/.

Results
Evidence that risk factors for myopia are mixed, comprising both positive (20) and null (17) findings. In 19 cohort studies on 3578 children, girls were more likely to develop myopia (RR: 1.28 [1.22–1.35]). Myopia can occur at any age, from early childhood to late adulthood. Children whose parents had myopia were more likely to develop myopia. Longer outdoor activities time (RR: 0.97 [0.95–0.98]) and less near-work time (RR: 1.05 [1.02–1.07]) appeared to be significantly decrease the incidence of myopia. Children with lower SE, longer AL, a lower magnitude of positive relative accommodation, worse presenting visual acuity, deeper anterior chamber, and thinner crystalline lens may be related to myopia onset. The burden of myopia in underprivileged countries is higher than in developed countries (RR: 5.28 [2.06–13.48]). The quality of evidence for the evaluated factors was moderate to low or very low.

Conclusions
Genetic factors, environmental factors (such as excessive use of electronic products, and poor study habits) and lifestyle factors (such as lack of outdoor activities, poor nutrition, etc.) are the main risk factors for myopia in children. Myopia prevention strategies should be designed based on environmental factors, gender, parental myopia and eye indicators in order to explore a lifestyle that is more conducive to the eye health of children.