bluuebunny/crossref_metadata_2025_split huggingface dataset:
MONITORING OF THE EPIZOOTIC SITUATION ON ANIMAL BRUCELLOSIS IN THE REPUBLIC OF KAZAKHSTAN
Authors: Таипова Айнура , I.S. Beishova , K. D. Alikhanov , В. K Otarbayev , V. A. Ulyanov , N.S. Ginayatov , L. Zh Dushaeva 
Published: September 2023

Brucellosis is a particularly dangerous zoonotic disease that is widespread in animals and humans. Despite the fact that more than 120 years have passed since the discovery of the pathogen and the disease has been well studied by domestic and foreign researchers, the problem of brucellosis remains relevant in many countries of the world. A number of economically developed countries have achieved some success in controlling bovine brucellosis caused by Brucella abortus. Results for control of brucellosis in small ruminants caused by Brucella melitensis are more modest. In some developing countries, the epizootic situation for bovine brucellosis is worsening. Brucellosis caused by B. melitensis is also a major public health problem.
According to the World Health Organization (WHO), more than 500 000 cases of newly diagnosed brucellosis are reported each year in more than 170 countries, more than half of them in the Eastern Mediterranean and Middle East. In brucellosis-prone regions, the actual incidence can be 10 to 25 times higher than officially reported. In brucellosis-endemic areas, where brucellosis is a deep-rooted problem, the infection has global, far-reaching negative consequences for the health and economy of states. The main objective of the studies was to monitor the epizootological situation of animal brucellosis in the Republic of Kazakhstan (RK).
Serum Selenium levels in Essential hypertension among adults at the University Teaching Hospital, Lusaka, Zambia
Authors: Chisulo AC , Lambwe N , Sijumbila G , Mukosha M 
Published: September 2023

In Zambia, essential hypertension is one of the commonest and prevalent non-communicable diseases. In the current medical literature it is not clear on the serum selenium levels among essential hypertensive patients in Zambia despite evidence in literature of its role in development of hypertension. The present study investigated serum selenium levels in essential hypertensive adults. We hypothesized that serum selenium levels were significantly lower in this population and was a risk factor for developing hypertension. An analytical cross-sectional design was applied to a total of 245 participants. Blood was collected for serum levels of Selenium, glucose, urea, creatinine and electrolytes. Student t-test was used to compare the serum selenium levels between hypertensive and normotensive participants. Significant (p<0.0001) lower levels of serum Selenium were observed in essential hypertensive adults (0.093mg/L ± 0.048)than in healthy normotensive adults (0.109mg/L ± 0.047). Regressionresults showed no significant relationship off Selenium levels with age (p=0.255), BMI (p-0.232), systolic blood pressure (p=0.175) and diastolic blood pressure (p=0.195).From these findings serum selenium levels may not be a risk factor for essential hypertension in this population. Nevertheless, more studies in the same geographical area are needed to confirm this.
Multiple antibiotic resistance iIndex of EscherichiaColi isolates in a tertiary hospital in south-west Nigeria
Authors: Joseph A.A , Odimayo M.S , Olokoba Lb , Olokoba AB , Popoola GO 
Published: September 2023

Background: The effectiveness of available antibiotics is reducing as microorganisms device means of evading its effects, resulting in the development of superbugs. Pathogens previously susceptible are becoming resistant, and spreading beyond the hospital environment. This change is a major concern for infection control and prevention and a huge economic burden for health care. This study aims to determine the drug sensitivity pattern of E. coli isolated in a tertiary hospital labMethodology: Gram negative bacilli, lactose fermenter, motile, indole positive, glucose fermenter, gas producing isolate were identified as E.coli. Antimicrobial susceptibility testing to commonly prescribed antibiotics was carried out using the modified Kirby Bauer method and reported with the Clinical and Laboratory Standard Institute Interpretative chart. Mulitiple Antibiotic Resistance index was calculated as number of antibiotics to which isolate is resistant divided by the total number of antibiotics against which isolate was tested.Result: Five hundred and twenty–seven isolates were identified, among which a high rate of resistance to cefuroxime (407), high rate of intermediate susceptibility to nalidixic acid (264) and high rate of sensitivity to ceftriaxone (388) was noted. Sixty percent of the isolates had an index 0.2. Of the 40% with Multiple Antibiotic Resistance index > 0.2, 61 % were from inpatient samples.Conclusion: The high Multiple Antibiotic Resistance index of the E. coli isolates indicates previous exposure to antibiotics and development of resistance to commonly prescribed antibiotics, hence, antimicrobial susceptibility testing is imperative in selecting therapeutic options. Attention also needs be paid to effective infection control and prevention to curb its spread among individuals.
A escuta e o tempo em uma unidade de urgência e emergência na perspectiva psicanalítica
Authors: Costa Antonia Mardeijane Albuquerque , Leitão Maria Lourdlayne Santiago , Leite Darla Moreira Carneiro , De Matos Tallys Newton Fernandes 
Published: September 2023

A pesquisa aborda a escuta e o tempo no ambiente hospitalar em uma unidade de urgência e emergência e discutindo as peculiaridades e perspectivas de cuidado por um viés da psicanálise. Trata-se de uma pesquisa teórico-clínico. No que se refere à questão prática, ela é representada por vinhetas clínicas cujo intuito é ilustrar como a vivência da escuta e do tempo no hospital ocorrem de modo concreto. A fundamentação teórica advém de Freud, Lacan e seus comentadores, ao abordar a psicanálise em extensão, o tempo lógico, a função da escuta na psicanálise, os tempos do cuidado, assim como os três tempos do trauma no adoecimento. A presença da psicanálise no hospital não é uma prática recente e inovadora. As discussões sobre a escuta psicológica na urgência e emergência evidenciam a importância de valorizar os aspectos subjetivos dos sujeitos internados, pois na maioria das vezes, o foco da equipe de saúde recai nas questões da doença que incidem no corpo. Então, o sujeito do inconsciente pode verbalizar suas incertezas e expressar seu sofrimento para um outro que esteja disponível a testemunhar, neste caso, para a psicóloga hospitalar.
The Development of Islamic Religious Education and Character Materials Online Based in Elementary Schools
Authors: Alirahman Agus Dian , Sumantri Mohamad Syarif , Japar Muhammad 
Published: September 2023

Purpose: The purpose of the study is to find and develop teaching materials for improving the outcomes of student learning in the subjects of Islamic Religious Education and Moral Character (PAdB) in Elementary Schools (SD).

Theoretical reference: The study utilizes the research and development (RnD) method as its theoretical framework. This method encompasses various research stages, including result examination, product development, testing, and iterative refinement. The study aligns with contemporary educational theories emphasizing the use of innovative teaching materials and online-based resources to enhance student engagement and understanding.

Method: The research employs the RnD method to design and validate new teaching materials. The process involves multiple stages, starting with result analysis, leading to the creation of online-based teaching materials for the PAdB subjects in elementary schools. These materials are rigorously tested and refined based on feedback and identified weaknesses.

Results and Conclusion: The following research findings have been identified: 1) students are actively involved in variations and innovations of online-based teaching materials in PAdB subjects in elementary schools in order to deliver intriguing experiences for students; 2) it is straightforward to access online-based teaching materials; 3) it is simple to understand and study material products in online-based teaching thoroughly; 4) providing learning opportunities for students through collaborative principles and the development of online-based PAdB learning material in elementary schools.

Implications of research: The study's implications are far-reaching. It highlights the effectiveness of online-based teaching materials in improving student outcomes in PAdB subjects. This finding has practical implications for educators and curriculum designers, emphasizing the importance of integrating digital resources into elementary school education. Additionally, the collaborative learning approach introduced through online materials opens new avenues for enhancing student engagement.

Originality/value: This research contributes to the field of education by presenting an innovative approach to teaching materials development and implementation. The use of online-based resources, combined with collaborative learning principles, is a novel and valuable strategy for improving student performance in PAdB subjects. This study's originality lies in its innovative pedagogical approach and its potential to transform elementary school education positively.
Integrated D-InSAR and Ground-based Radar for Open Pit Slope Stability Monitoring and Implications for Rock Mass Young’s Modulus Reduction
Authors: Maulana Faris Ridwan , Wattimena Ridho Kresna , Sulistianto Budi 
Published: September 2023

Excavation and material stockpiling activities in the mining process cause a change in the distribution of forces and stresses in the material. As a result, the material will seek a new equilibrium by releasing the load through a landslide. As part of mitigation, it is necessary to monitor displacements occurring on slopes using high-accuracy devices. Ground-based radar is a technique considered to have good ability to detect displacements in real-time. However, ground-based radar has a weakness in that it cannot detect vertical displacement. One of the emerging technologies that is used for monitoring vertical displacements as LoS displacements is D-InSAR analysis. With the integration of both methods, displacements that occur horizontally and vertically on a slope can be detected properly. In addition, the decrease in rock mass strength due to displacement can be predicted based on numerical analysis using the finite element method. Monitoring was carried out from December 10th, 2021 to April 9th, 2022. The monitoring results from the beginning to the end of the period showed that the horizontal and vertical displacements that occurred in the low wall area were 1247.34 mm and 292.5 mm, respectively. Correlated with these conditions, the Young’s modulus value of the rock mass decreased between 3% and 35%.
Inteligencia artificial generativa para fortalecer la educación superior
Authors: Chávez Solís María Elena , Labrada Martínez Esther , Carbajal Degante Eric , Pineda Godoy Erika , Alatristre Martínez Yadira 
Published: September 2023

La transformación digital acelerada conlleva una serie de adaptaciones y reestructuración en los procesos de enseñanza aprendizaje que implica evaluar los riesgos y aportaciones para su adopción. Como ejemplo, se tiene a la Inteligencia Artificial Generativa, que representa un gran dilema para docentes y estudiantes. Su característica es la generación autónoma de texto, imágenes, voz y contenido en general, lo que se aprecia como una gran aportación a la eficiencia y productividad. Sin embargo, conlleva la reflexión y el cuestionamiento del rumbo que tomará la educación bajo la adopción de un proceso automatizado para la generación de este tipo de recursos. Ante esta perspectiva, el objetivo de esta investigación es evaluar las aportaciones de la Inteligencia Artificial Generativa en la educación de nivel superior para proponer una estrategia que fortalezca el aprendizaje. La metodología implementada se fundamenta en el método cualitativo para su consecución bajo el muestreo intencional, con una estrategia de caso de conveniencia en estudiantes de nivel superior en universidades públicas de México, analizando el uso de la tecnología. Los principales resultados advierten la necesidad de la mejora continua en el uso y aprovechamiento de la tecnología y de la innovación tecnológica, bajo la toma de decisiones informadas.
Green synthesis of UV absorber (E)-2-(((4-(benzyloxy)phenyl)imino)methyl)phenol by microwave method
Authors: Nguyen Thi Kieu-Khanh , Nguyen Anh-Thu , Ho Pham Anh - Vu , Le Viet-Hai , Nguyen Ngoc-An , Huynh Le Thanh-Nguyen , Co Thanh-Thien , Nguyen Hoang-Thai , Ton That-Quang 
Published: September 2023

In this work, a UV absorber compound (E)-2-(((4-(benzyloxy)phenyl)imino)methyl)phenol was synthesized by microwave method using a two steps protocol. In the first step, α-(4-hydroxyphenylimino)-o-cresol (1) was synthesized from 4-aminophenol and salicylaldehyde by circulating under microwave heating at 60 oC for 8 minutes, the reaction yield reached 82.91 %. In the second step (E)-2-(((4-(benzyloxy)phenyl)imino)methyl)phenol (2) was synthesized from precursor (1) and benzyl bromide by circulating under microwave heating at 80 oC for 3 minutes, the reaction yield reached 25.08 %. The overall yield for the synthesis of UV absorber 2 was 20.79 %. The molecular structures of precursor (1) and product (2) were analysed by high performance liquid chromatography - mass spectrometry (LC/MS) and nuclear magnetic resonance (NMR) methods. The UV absorbance of precursor (1) and product (2) was investigated by UV absorption spectrometry. The obtained results show that product (2) has a higher UV absorption intensity than precursor (1), the UV absorption region extends from 240 nm to 390 nm, the maximum absorption peak is at the wavelength (λmax) of 350 nm. The UV absorber (E)-2-(((4-(benzyloxy)phenyl)imino)methyl)phenol with cyclic structure, low molecular weight, and high UV absorbance has potential application as an UV absorber for greenhouse covering plastic, paint and ink systems.
Kırım Kongo Kanamalı Ateşi Tanılı Hastaların Epidemiyolojik, Klinik ve Laboratuvar Özelliklerinin Değerlendirilmesi: Tek Merkez Deneyimi
Authors: ÇİÇEK Yeliz , ÇELİK Mehmet 
Published: September 2023

Amaç: Kırım Kongo Kanamalı Ateşi (KKKA) çoğu zaman kene teması ile bulaşan, ateş ve kanamalar ile seyreden viral bir zoonotik hastalıktır. Bu çalışmada, hastanemizin Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji kliniğinde son 11 yılda Kırım Kongo Kanamalı Ateşi tanısıyla takip edilen hastaların epidemiyolojik, klinik ve laboratuvar özelliklerinin incelenmesi amaçlandı.
Yöntemler: Çalışmaya Ocak 2011-Aralık 2022 tarihleri arasında Kırım Kongo Kanamalı Ateşi tanısıyla takip edilen 18 yaşından büyük hastalar dahil edildi. Hastaların yaş, cinsiyet, meslek vb. sosyodemografik özellikleri, başvuru şikayetleri, kene temas öyküleri, laboratuvar parametreleri, hastanede yatış süreleri ve 3 aylık sağ kalımları retrospektif olarak hasta dosyalarındaki verilerden incelendi. Hastalık tanısında ELISA (enzyme linked immunosorbent assay) ile virüs spesifik IgM’nin saptanması ya da RT-PCR (Reverse Transcriptase-Polymerase Chain Reaction) ile viral RNA tespiti esas alındı.
Bulgular: Toplam 106 hastanın 73 (%68,9) erkek, 33 (%33,1)’ü kadındı. Yaş ortalaması 49,43±14,16 yıldı. Hastaların 105 (%99,1)’i kırsal bölgede yaşamaktaydı. Kene temas öyküsü olan 76 (71.7%) hasta olup bunlardan 58 (%76,3)’i keneyi kendi imkanlarıyla çıkardığını ifade etti. En fazla başvurunun olduğu ay hazirandı (n=55, %51,8). 2022 yılı (n=38, %35,9) en fazla hasta tespit edilen yıl oldu. Semptomların başlangıcı ile hastaneye başvuru arasındaki süre 3,14±7,66 (min 1-maks 13) gün olarak saptandı. İlk başvuruda en fazla yaygın vücut ağrısı (n=101, %95,3), halsizlik (n=101, 95,3), ateş (n=81, %76,4) şikayetleri tariflenirken, fizik muayenede en sık saptanan bulgular ise yüksek ateş (n=79, %74,5), hematüri (n=9, %8,5), hipotansiyon ve taşikardiydi (n=8, %7,5). Hastalardan 42 (%39,6)’si 3. Basamak bir merkeze sevk edilirken, 64 (%60,4)’ü şifa ile taburcu edildi. Bir hasta ise sevk edildiği 3. Basamak merkezde vefat etti.
Sonuç: Bu çalışmada hayvancılıkla uğraşanların/çiftçilerin ve erkeklerin hastalığa daha fazla yakalandığı, hastalık bulaşında kene temas öyküsünün önemli ölçüde tariflendiği, özellikle haziran ayında vakaların daha sık ortaya çıktığı belirlendi. Özellikle hastalık sıklığının artış gösterdiği ilkbahar ve yaz aylarında şüpheli klinik bulgularla gelen hastalarda kene temas öyküsü mutlaka sorgulanmalı ve KKKA ön tanısı göz ardı edilmemelidir.
Creation of a Quality Payment Program Measure for Mismatch Repair or Microsatellite Instability Biomarker Testing Status in Colorectal, Endometrial, Gastroesophageal, or Small Bowel Carcinoma
Authors: Bocsi Gregary T. , Laudadio Jennifer , Jain Richa , Eakin Sarah M. , Bhalla Amarpreet , Rosenberg Jonathan A. , Maratt Jennifer K. , Kupfer Sonia S. , Leiman David A. , Cardona Diana M. 
Published: September 2023

Context.—
Quality measures that are supported by evidence-based clinical practice guidelines are preferred for assessing the quality of pathologists' practices. Careful testing of a measure ensures that scores obtained by that measure reflect the quality of a pathologist's practice.

Objective.—
To specify a new quality measure and to demonstrate through testing that it is suitable for measuring pathologists' appropriate incorporation of information regarding microsatellite instability (MSI) and/or mismatch repair (MMR) status in pathology reports for colorectal, endometrial, gastroesophageal, and small bowel carcinoma.

Design.—
The College of American Pathologists collaborated with the American Gastroenterological Association to specify and test the new measure. Face validity testing was used to investigate the validity of the measure. Feasibility testing was conducted to understand if data elements required by the measure specification were readily accessible. Signal-to-noise analysis was used to characterize the measure's reliability.

Results.—
Guideline recommendations for MSI and/or MMR testing supported specifications for the measure. Face validity testing indicated that the measure could distinguish the quality of care provided. Data elements required by the measure specification were found to be accessible, which supported the measure's feasibility. Reliability testing showed that differences in measure score were attributable to real differences in performance rather than random variation in scoring.

Conclusions.—
The Mismatch Repair or Microsatellite Instability Biomarker Testing Status in Colorectal Carcinoma, Endometrial, Gastroesophageal, or Small Bowel Carcinoma measure was appropriately specified, and testing demonstrated that it is well suited for characterizing the quality of pathologists' communication of MMR and/or MSI status.
Synthesis of bi- and trifunctional mesoporous silica-based catalyst and application in one-pot cascade reactions
Authors:   , Klayanon Apichat 
Published: September 2023

This work reports the synthesis and full characterization of bifunctional mesoporous silica supported acid (-SO3H)-base (-NH2) catalysts and trifunctional mesoporous silica supported acid-base-metal catalysts as well as their applications. A series of bifunctional catalysts were synthesized with different site separations, acid loadings, base loadings and types of aminosilane, namely N2SA2, SA0.5N0.5, SA0.5N2, SA1N2, SA2N2, SA0.5N4, SA0.5NN4 and SA0.5NNN4, via a co-condensation and post-synthetic grafting methods and were characterized by XRD, FT-IR, N2 adsorption-desorption, SEM, TEM, TGA and XPS techniques. The well-ordered hexagonal mesoporous structure was preserved throughout the synthesis where the synthesized materials exhibited small kidney-bean-shaped rod and highly ordered hexagonal mesoporous structures. The surface area, acidity, and basicity of the bifunctional catalysts were in the ranges of 609-729 m2 g-1, 0.88-1.10 mmol g-1, and 0.29-0.57 mmole g-1, respectively. These catalysts were tested in the one-pot deacetylation-Knoevenagel of benzaldehydedimethylacetal (A) with malononitrile to produce benzylidenemalononitrile (C) at 90 oC for 5 h. It was found that the conversion of A and the yield of C were influenced by the acidity, basicity and pore characteristics of the catalysts. In particular, The SA0.5N4 catalyst exhibited the highest conversion of A (100%) and the highest yield of C (71%) with good reusability of at least four cycles where no significant loss in catalytic activity was observed.

The best performing bifunctional catalyst was further used for the preparation of trifunctional catalysts, where the latter were prepared by impregnation of palladium metal (0.03, 0.2 and 1 wt.%) on the SA0.5N4 acid-base material. The trifunctional catalysts were tested in the one-pot deacetylation-Knoevenagel-hydrogenation of A to produce benzylmalononitrile (D). The effects of reaction time, hydrogen pressure, Pd loading and type of aminosilanes on the catalytic performance were investigated. Nevertheless, the desired product (D) was not observed in any treatment conditions. The production of D was, on the other hand, achieved by using the physical mixture of 5%Pd/Al2O3 and either of the SA0.5N4, SA0.5NN4, and SA0.5NNN4 catalysts. The SA0.5N4 catalyst continued to perform well for the one-pot production of D, where the highest yield of D (49.4 %) was achieved over the consecutive deacetylation-Knoevenagel-hydrogenation process catalyzed by the physical mixture of SA0.5N4 and 5%Pd/Al2O3.
การคัดแยก Beauveria bassiana (Balsamo) Vuillemin ไอโซเลทที่รอดชีวิตในภาวะอุณหภูมิสูงซึ่งสามารถควบคุมเพลี้ยกระโดดสีน้ำตาล Nilaparvata lugens (Stål)
Authors:   , วงศ์วานิช ญาณิศา 
Published: September 2023

Beauveria bassiana เป็นราที่ใช้ในการควบคุมแมลงอย่างแพร่หลาย อย่างไรก็ตาม เมื่ออุณหภูมิเพิ่มสูงขึ้นจะส่งผลให้ความสามารถในการควบคุมแมลงของราลดลง การคัดแยก
B. bassiana ที่มีความสามารถในการเจริญได้ในที่อุณหภูมิสูงและมีความสามารถในการควบคุมแมลงที่อุณหภูมิที่สูงกว่าอุณหภูมิที่เหมาะสมต่อการเจริญเติบโตของรา เป็นอีกหนทางหนึ่งในการเพิ่มประสิทธิภาพในการควบคุมเพลี้ยกระโดดสีน้ำตาลที่อุณหภูมิสูง B. bassiana จำนวน 3 ไอโซเลท ที่มีความสามารถในการควบคุมแมลงสูง ได้รับความอนุเคราะห์จากกรมการข้าว ถูกเลือกมาชักนำให้เกิดการกลายพันธุ์ด้วยสาร ethyl methanesulfonate (EMS) จากนั้นนำมาคัดแยกที่อุณหภูมิ 31 33 และ 35°C พร้อมกับศึกษาความสามารถในการฟื้นฟูของราหลังจากที่ผ่านอุณหภูมิ 33°C เป็นระยะเวลา 7 วัน จากนั้นย้ายไปบ่มที่ 25°C ดูประสิทธิภาพการงอกของสปอร์ที่ 25°C (หลังจากบ่มที่ 33°C เป็นระยะเวลา 5 10 และ 15 วัน) และนำเชื้อสายพันธุ์กลายที่ได้ไปทดสอบความสามารถในการควบคุมเพลี้ยกระโดดสีน้ำตาล จากผลการศึกษาพบไอโซเลท B. bassiana สายพันธุ์กลาย 1
ไอโซเลท ที่มีขนาดโคโลนีที่ใหญ่กว่า และสร้างสปอร์ที่มากกว่าราต้นแบบ ที่อุณหภูมิ 33°C ซึ่งเป็นอุณหภูมิที่สูงที่สุด เนื่องจากที่อุณหภูมิ 35°C ไม่พบการเจริญเติบโตของราในทุกไอโซเลท ผลทดสอบการฟื้นฟูของรา พบราสายพันธุ์กลายมีขนาดโคโลนีและปริมาณสปอร์ที่มากกว่าราต้นแบบ ผลการทดสอบการงอกของสปอร์ที่อุณหภูมิ 33°C ไม่พบการงอกของสปอร์ราทั้งไอโซเลทสายพันธุ์กลายและต้นแบบ แต่เมื่อย้ายสปอร์ไปเลี้ยงที่ 25°C (หลังจากการเลี้ยงที่ 33°C) ไอโซเลทสายพันธุ์กลายมีเปอร์เซ็นต์การงอกที่มากกว่าราต้นแบบในทุกชุดการทดลอง และความสามารถในการควบคุมเพลี้ยกระโดดสีน้ำตาล Nilaparvata lugens (Stål) ของราสายพันธุ์กลายมีค่ามากกว่าราต้นแบบ