bluuebunny/crossref_metadata_2025_split huggingface dataset:
Specific effects of five subtypes of childhood maltreatment on suicide behaviours in Chinese adolescents: the moderating effect of sex and residence
Authors: Peng Chang , Cheng Junhan , Rong Fajuan , Wang Yan , Tan Yafei , Yu Yizhen 
Published: July 2023

Abstract

Aims
Although childhood maltreatment has been widely supported to be a robust predictor of suicide behaviours, the effects of different childhood maltreatment subtypes remain controversial and inconclusive. Moreover, whether the effects differ by sex in urban and rural adolescents is still unknown. This study aimed to quantify the associations between five subtypes of childhood maltreatment and different suicide behaviour involvement.

Methods
A multistage cluster sampling method was adopted from April to December 2021 for adolescents aged 12 to 18 across five representative provinces of China. The Childhood Trauma Questionnaire-Short Form was used to measure childhood maltreatment subtypes. Suicide behaviour involvement was classified as none group, suicide ideator, suicide planner and suicide attempter. Confounding variables include demographic characteristics, smoking, drinking alcohol, depression and anxiety.

Results
Among a total of 18,980 adolescents, 2021 (10.6%) were suicide ideator, 1595 (8.4%) were suicide planner and 1014 (5.3%) were suicide attempter. Rural females had the highest proportion of suicide ideator (13.8%) and suicide planner (11.5%). Multinomial logistic regression analysis indicated that five childhood maltreatment subtypes were independently associated with suicide behaviours, except for associations between sexual abuse and suicide ideator as well as suicide planner (p > 0.05). Moreover, these associations differ by sex and residence. After adjusted for interactions of different subtypes, structural equation model indicated that the direct effects of childhood maltreatment subtypes on suicide behaviours from high to low were emotional abuse (β = 0.363, p < 0.001), physical abuse (β = 0.100, p < 0.001) and sexual abuse (β = 0.033, p = 0.003), while the effects of physical neglect and emotional neglect were not significant (p > 0.05).

Conclusions
Five subtypes of childhood maltreatment have specific and non-equivalence associations with suicide behaviours. Emotional abuse may have the strongest effect, and sexual abuse have an acute effect on suicide behaviours. Suicide prevention programs for Chinese adolescents could focus on those who experienced emotional, physical and sexual abuse. Furthermore, strategies should be tailored by sex and residence, and rural females deserve more attention.
Statistical Study on Plasma Velocities in the Bottom‐Side Ionosphere Over Low Latitude Hainan Station: Digisonde Measurement
Authors: Wang Guojun , Shi Jiankui , Torkar Klaus , Wang Zheng , Wang Xiao , Cheng Zhengwei , Shang Sheping 
Published: July 2023

AbstractData measured by the Digisonde at the low‐latitude station Hainan from 2003 to 2016 are statistically analyzed to specify the diurnal average variations of the bottom‐side F region ionospheric plasma velocity vector V. This is the first comprehensive analysis of Digisonde measurements of low latitude F region plasma velocities in the East Asian sector that use a database covering more than one solar cycle. The velocity components VN (Northward), VE (Eastward), and VZ (Upward) are analyzed for two levels of solar flux and two levels of geomagnetic activity, respectively. The diurnal variations of the average VZ show three positive peaks near the prereversal enhancement (PRE) period, pre‐midnight, and before sunrise, respectively, and a prominent valley in the early morning. The averaged VZ significantly increased with solar flux in the period of PRE during equinoxes, but it was only slightly affected by Kp. The VE component was westward in daytime and eastward in nighttime. The average eastward VE increased significantly with solar flux but decreased with Kp, whereas the average westward VE exhibited only a small variation with solar flux and Kp. The average VN was almost southward independent of solar flux and Kp. The plasma velocities over the Hainan station were mainly caused by the electric field and neutral wind. Our results show that the features of the vertical and meridional velocities over the Hainan station in the morning are associated with the formation of the equatorial ionization anomaly (EIA).
The Late Mesozoic Intracontinental contraction–Extension Transition in the Beishan Fold‐Thrust Belt, Central Asia: Constraints From Structural Analysis and Apatite (U–Th)/He Thermochronology
Authors: Liu Kui , Chen Xuanhua , Zuza Andrew V. , Shao Zhaogang , Qin Xiang , Han Lele , Zhang Yiping , Yu Wei , Wang Zengzhen , Shi Xiaobin , Li Bing , Wang Ye 
Published: July 2023

AbstractThe late Mesozoic Beishan fold‐thrust belt occupies a key position in central Asia, figuring importantly in our understanding of intracontinental deformation in response to far‐field plate‐boundary forces. To determine when and how the Beishan fold‐thrust belt was developed, we conducted detailed field mapping, structural analysis, and apatite (U–Th)/He (AHe) thermochronology in the Hongliudaquan area, southeastern Beishan Range. The study area exposes the Hongliudaquan fold and thrust system, consisting of the southern Hongliudaquan thrust nappe and autochthonous fold sets. The nappe experienced >16 km northward thrust‐induced translation. The autochthonous fold sets strongly deformed Lower–Middle Jurassic strata showing diverse trends of kilometer‐scale basins and ranges. We interpret that this fold interference pattern was produced in a constrictional deformation field, which underwent synchronous shortening in two orthogonal directions. This stain history was related to synchronous imbricate thrusting, duplex formation, and strike‐slip faulting at different structural levels. Restoration of the Hongliudaquan fold and thrust system yields a minimum of ∼27% (∼10.1 km) north–south shortening strain. Thrusting and nappe emplacement within the Beishan fold‐thrust belt may have started in the late Middle Jurassic and persisted until the Early Cretaceous (∼140–133 Ma). Our AHe data also record ∼124–115 Ma cooling related to footwall exhumation during subsequent normal faulting, indicative of the late Mesozoic intracontinental contraction–extension transition. The Beishan fold‐thrust belt initiated in central Asia via the late Mesozoic reactivation of the Paleozoic–early Mesozoic Beishan orogen as a result of the far‐field responses to multi‐directional plate convergence around Asia.
500‐Year Periodic Vegetation and Monsoonal Climate Oscillations During the Last Deglaciation in East Asia
Authors: Xu Deke , Chu Guoqiang , Shen Caiming , Sun Qing , Wu Jing , Li Fengjiang , Dong Yajie , Cui Anning , Wu Naiqin , Lu Houyuan 
Published: July 2023

AbstractFluctuations in monsoonal climate on orbital‐ to millennial‐timescales have had a major impact on vegetation change in East Asia since the last deglaciation. However, the influence of centennial‐scale oscillations on the spatio‐temporal characteristics of vegetation and climate during the last deglaciation remains controversial. We present a well‐dated, decadal‐resolution pollen record from the sediments of annually laminated Lake Xiaolongwan in Northeast Asia, which reveals major orbital‐/millennial‐scale and minor quasi‐periodic, that is, ∼500‐year (yr) cyclic, vegetation changes from ∼19.96 to ∼10.79 Kyr ago (covering the last deglaciation). The ∼500‐yr cycles are characterized by alternations in broadleaved forest/boreal coniferous forest with tundra steppe representing warm and humid/cold and dry phases of the monsoonal climate. This cyclicity may be related to El Niño‐like/La Niña‐like state and low‐latitude atmosphere‐ocean processes, against the background of the long‐term trend of the deglacial climatic evolution. Our findings demonstrate a close relationship between ecosystem succession and climate change on centennial scale.
Minimally invasive techniques for lateral maxillary sinus floor elevation: small lateral window and one-stage surgery—a 2–5-year retrospective study
Authors: Gao Shaojingya , Jiang Yao , Yao Yangxue , Li Songhang , Cai Xiaoxiao 
Published: July 2023

AbstractThis study aimed to introduce a minimally invasive technique for maxillary sinus floor elevation using the lateral approach (lSFE) and to determine the factors that influence the stability of the grafted area in the sinus cavity. Thirty patients (30 implants) treated with lSFE using minimally invasive techniques from 2015 to 2019 were included in the study. Five aspects of the implant (central, mesial, distal, buccal, and palatal bone heights [BHs]) were measured using cone-beam computed tomography (CBCT) before implant surgery, immediately after surgery (T0), 6 months after surgery (T1), and at the last follow-up visit (T2). Patients’ characteristics were collected. A small bone window (height, (4.40 ± 0.74) mm; length, (6.26 ± 1.03) mm) was prepared. No implant failed during the follow-up period (3.67 ± 1.75) years. Three of the 30 implants exhibited perforations. Changes in BH of the five aspects of implants showed strong correlations with each other and BH decreased dramatically before second-stage surgery. Residual bone height (RBH) did not significantly influence BH changes, whereas smoking status and type of bone graft materials were the potentially influential factors. During the approximate three-year observation period, lSFE with a minimally invasive technique demonstrated high implant survival rate and limited bone reduction in grafted area. In conclusion, lSFE using minimally invasive techniques was a viable treatment option. Patients who were nonsmokers and whose sinus cavity was filled with deproteinized bovine bone mineral (DBBM) had significantly limited bone resorption in grafted area.
At a glance: the largest Niemann-Pick type C1 cohort with 602 patients diagnosed over 15 years
Authors: Guatibonza Moreno Pilar , Pardo Luba M. , Pereira Catarina , Schroeder Sabine , Vagiri Deepthi , Almeida Ligia S. , Juaristi Carlos , Hosny Heba , Loh Clarice C. Y. , Leubauer Anika , Torres Morales Galina , Oppermann Sebastian , Iurașcu Marius-Ionuț , Fischer Steffen , Steinicke Tara-Marisa , Viceconte Nikenza , Cozma Claudia , Kandaswamy Krishna Kumar , Pinto Basto Jorge , Böttcher Tobias , Bauer Peter , Bertoli-Avella Aida 
Published: July 2023

AbstractNiemann-Pick type C1 disease (NPC1 [OMIM 257220]) is a rare and severe autosomal recessive disorder, characterized by a multitude of neurovisceral clinical manifestations and a fatal outcome with no effective treatment to date. Aiming to gain insights into the genetic aspects of the disease, clinical, genetic, and biomarker PPCS data from 602 patients referred from 47 countries and diagnosed with NPC1 in our laboratory were analyzed. Patients’ clinical data were dissected using Human Phenotype Ontology (HPO) terms, and genotype–phenotype analysis was performed. The median age at diagnosis was 10.6 years (range 0–64.5 years), with 287 unique pathogenic/likely pathogenic (P/LP) variants identified, expanding NPC1 allelic heterogeneity. Importantly, 73 P/LP variants were previously unpublished. The most frequent variants detected were: c.3019C > G, p.(P1007A), c.3104C > T, p.(A1035V), and c.2861C > T, p.(S954L). Loss of function (LoF) variants were significantly associated with earlier age at diagnosis, highly increased biomarker levels, and a visceral phenotype (abnormal abdomen and liver morphology). On the other hand, the variants p.(P1007A) and p.(S954L) were significantly associated with later age at diagnosis (p < 0.001) and mildly elevated biomarker levels (p ≤ 0.002), consistent with the juvenile/adult form of NPC1. In addition, p.(I1061T), p.(S954L), and p.(A1035V) were associated with abnormality of eye movements (vertical supranuclear gaze palsy, p ≤ 0.05). We describe the largest and most heterogenous cohort of NPC1 patients published to date. Our results suggest that besides its utility in variant classification, the biomarker PPCS might serve to indicate disease severity/progression. In addition, we establish new genotype–phenotype relationships for “frequent” NPC1 variants.
Should we splint traumatised primary teeth?
Authors: Deery Chris 
Published: July 2023

Abstract
Design
Systematic review.

Review question
Does splinting of traumatised primary teeth improve clinical outcomes?

Case selection
Clinical studies published after 2003 reporting trauma (luxation, root fracture or alveolar fracture) to primary teeth, with a minimum follow-up of 6 months, were eligible for inclusion. Case reports were excluded, but case series were included. Studies reporting the outcome of splinting following avulsion injuries were excluded, as current guidance does not recommend re-implantation of teeth for these injuries.

Data analysis
Two researchers independently assessed the risk of bias in the included studies, with a third researcher resolving any disagreements. The same two independent researchers conducted a quality assessment of the included studies.

Results
Three retrospective studies met the inclusion criteria. Only one of these studies had a control group. High success rates were reported for the management of teeth with root fractures. A benefit for splinting teeth with lateral luxation was not identified. No alveolar fractures were included.

Conclusions
This review suggests that the outcome of the management of root fractures in primary teeth may benefit from flexible splinting. However, the evidence base is low.
Haplotype-resolved chromosomal-level assembly of wasabi (Eutrema japonicum) genome
Authors: Tanaka Hiroyuki , Hori Tatsuki , Yamamoto Shohei , Toyoda Atsushi , Yano Kentaro , Yamane Kyoko , Itoh Takehiko 
Published: July 2023

AbstractIn Japan, wasabi (Eutrema japonicum) is an important traditional condiment, and is recognized as an endemic species. In the present study, we generated a chromosome-level and haplotype-resolved reference genome for E. japonicum using PacBio CLR (continuous long reads), Illumina, and Hi-C sequencing data. The genome consists of 28 chromosomes that contain 1,512.1 Mb of sequence data, with a scaffold N50 length of 55.67 Mb. We also reported the subgenome and haplotype assignment of the 28 chromosomes by read-mapping and phylogenic analysis. Three validation methods (Benchmarking Universal Single-Copy Orthologs, Merqury, and Inspector) indicated that our obtained genome sequences were a high-quality and high-completeness genome assembly. Comparison of genome assemblies from previously published genomes showed that our obtained genome was of higher quality. Therefore, our genome will serve as a valuable genetic resource for both chemical ecology and evolution research of the genera Eutrema and Brassicaceae, as well as for wasabi breeding.
Deep learning framework for sensor array precision and accuracy enhancement
Authors: Payette Julie , Vaussenat Fabrice , Cloutier Sylvain 
Published: July 2023

AbstractIn the upcoming years, artificial intelligence is going to transform the practice of medicine in most of its specialties. Deep learning can help achieve better and earlier problem detection, while reducing errors on diagnosis. By feeding a deep neural network (DNN) with the data from a low-cost and low-accuracy sensor array, we demonstrate that it becomes possible to significantly improve the measurements’ precision and accuracy. The data collection is done with an array composed of 32 temperature sensors, including 16 analog and 16 digital sensors. All sensors have accuracies between $$0.5 - 2.0\;^{^\circ } {\text{C}}$$

0.5
-
2.0

∘

C

. 800 vectors are extracted, covering a range from to 30 to $$45\;^\circ \hbox {C}$$

45

∘

C

. In order to improve the temperature readings, we use machine learning to perform a linear regression analysis through a DNN. In an attempt to minimize the model’s complexity in order to eventually run inferences locally, the network with the best results involves only three layers using the hyperbolic tangent activation function and the Adam Stochastic Gradient Descent optimizer. The model is trained with a randomly-selected dataset using 640 vectors (80% of the data) and tested with 160 vectors (20%). Using the mean squared error as a loss function between the data and the model’s prediction, we achieve a loss of only 1.47x10$$^{-4}$$

-
4

on the training set and 1.22x10$$^{-4}$$

-
4

on the test set. As such, we believe this appealing approach offers a new pathway towards significantly better datasets using readily-available ultra low-cost sensors.
A portable molecularly imprinted polymer-modified microchip sensor for the rapid detection of perfluorooctanoic acid
Authors: Wei Yingmei , Liu Hongjie , Wang Shaopeng , Yu Kefu , Wang Liwei 
Published: July 2023

Cu2O@C@NiCo2O4 was introduced to the MIP sensor to enhance the PFOA sensitivity, which achieved an LOD of 19.65 ng L−1 with a wide linear range of 207–4140 ng L−1. This MIP sensor was also applied in a disposable microchip sensor for PFOA detection.
Colorimetric sensor arrays for antioxidant recognition based on Co3O4 dual-enzyme activities
Authors: Hao Pingping , Liu Zhenchao , Wang Zhiwei , Xie Min , Liu Qingyun 
Published: July 2023

A sensor array based on the double enzyme–like activity of Co3O4 nanozymes was constructed to identify four different antioxidants. Due to the double enzyme–like activity of Co3O4, oxTMB appears blue with different degrees in the presence and absence of H2O2.
Ovarian cancer G protein-coupled receptor 1 deficiency exacerbates crystal deposition and kidney injury in oxalate nephropathy in female mice
Authors: Yassini Nima , Sprenger Janine , Pastor Arroyo Eva Maria , Krudewig Christiane , Pellegrini Giovanni , Joller Nicole , Wagner Carsten A. , Imenez Silva Pedro Henrique 
Published: July 2023

Abstract
Ovarian cancer G protein-coupled receptor 1 (OGR1) (Gpr68) and G protein-coupled receptor 4 (GPR4) (Gpr4) are proton-activated G protein-coupled receptors that are stimulated upon increased extracellular acidity. These receptors have various physiological and pathophysiological roles in renal acid–base physiology, tissue inflammation, and fibrosis among others. Their function in injured renal tissue, however, remains mostly unclear. To address this, we investigated their role in crystalline nephropathy by increasing the oxalate intake of GPR4 KO and OGR1 KO mice.
After 10 days of high-oxalate intake and 4 days of recovery, renal crystal content, histopathology, filtration function, and inflammation were assessed. While GPR4 deficiency did not show major alterations in disease progression, OGR1 KO mice had higher urinary calcium levels and exacerbated crystal accumulation accompanied by decreased creatinine clearance and urea excretion and a decreased presence of regulatory T (Treg) cells in kidney tissue. When lowering the severity of the kidney injury, OGR1 KO mice were more prone to develop crystalline nephropathy. In this setting, OGR1 KO mice displayed an increased activation of the immune system and a higher production of proinflammatory cytokines by T cells and macrophages.
Taken together, in the acute setting of oxalate-induced nephropathy, the lack of the proton-activated G protein-coupled receptor (GPCR) GPR4 does not influence disease. OGR1 deficiency, however, increases crystal deposition leading to impaired kidney function. Thus, OGR1 may be important to limit kidney crystal deposition, which might subsequently be relevant for the pathophysiology of oxalate kidney stones or other crystallopathies.
Persian Version of the Hyperacusis Questionnaire: Psychometric Evaluation and Prevalence Determination
Authors: Nazeri Ahmadreza , Fathollahzadeh Farnaz , Azizi Mahdi 
Published: July 2023

Purpose:Hyperacusis is an uncommon hearing disorder, known as increased sensitivity to daily surrounding sounds. This disorder can profoundly affect people's daily activities. The studies conducted about hyperacusis are very limited in Iran. The purposes of this study are the psychometric evaluation of the Persian version of the Hyperacusis Questionnaire (PHQ) and the investigation of its prevalence.Method:This cross-sectional study was accomplished on 203 young university students with normal hearing sensitivity. After translating the questionnaire, the psychometric properties of the PHQ were evaluated by content validity ratio (CVR) and index (CVI) and exploratory factor analysis (EFA). Students were evaluated by clinical audiology tests, the loudness discomfort level (LDL) measurement, and answering the PHQ.The research data collection was done from April to November 2022. Otoscopy, clinical and speech audiometry, and LDL were all executed, respectively. The participants directly answered the PHQ. All statistical analyses were performed using SPSS software Version 26.Results:The PHQ demonstrated acceptable validity and reliability, Cronbach's alpha (.81), CVI (> 0.88), and CVR (> 0.98). EFA revealed four dimensions of the questionnaire. Of the participants, four (2%) were identified as suffering from hyperacusis. The PHQ showed the possibility of differences between genders.Conclusions:The psychometric evaluations of the PHQ were found to be acceptable and can be used in future studies. The prevalence of hyperacusis in our sample was 2%, and estimated to be higher in females. These findings suggest the need for further research on hyperacusis in Iranian population and specified studies to compare the two genders.
A conditioned reflex action embedded associative context learning‐based energy efficient paradigm in smart city milieu
Authors: Hussain Majid , Bilal Ahmad , Faheem Muhammad , Anwar Muhammad , Zia Muhammad Sultan 
Published: July 2023

AbstractAn intelligent video surveillance system is crucial to enhance public safety, crime prevention, traffic, and crowd management in a smart city milieu. Situational awareness is an essential aspect of these surveillance systems and it is inferred through underlying context aware frameworks. However, these systems may not possess the ability to proactively disseminate the real‐time context among its sensor nodes. Moreover, in the specific conditions of occurrence of related or repeated events, these systems may also perform inefficiently through afresh context processing and disseminate cycles, without learning from the relevant context that has already been occurred and processed by the system. It leads to deteriorated performance, especially delay in reaction, overwhelmed processing, and energy expenditures. Therefore, to counter such issues, this research work proposes an energy efficient situational aware framework deployed in visual sensors network that is incorporated with context associative learning. System observes currently occurring context at each instance of an event. Overtime, context is refined and stored in context database. Such mechanism empowers the system to learn from previous experiences and develop relationship among the subsequent events that is embedded through this associative (adaptive) learning. Eventually, each event is processed through intelligent resource allocation, supported through mechanism of context learning that further illustrates the independent functions of reduced processing and improved (rapid) decision making resulting in evolution of energy efficient computing paradigm. Ultimately, the capability of learned reflex‐action is induced through introspectively evolved context of the system in entirety and against specific condition of recurred situation depicting minimum energy expenditure.