bluuebunny/crossref_metadata_2025_split huggingface dataset:
PAIN WITH A NEUROPATHIC COMPONENT IN COMBATANTS AFTER GUNSHOT WOUNDS
Authors: Horoshko V.R. , Kuchyn Iu.L. 
Published: August 2023

Background. In combatants with gunshot wounds, the frequency of pain chronicization is observed in 63.4-78.5% of cases. The reason for this high frequency of chronicization may be a neuropathic component. However, this hypothesis remains unexplored.
Aim: To study the frequency of neuropathic pain in combatants after gunshot wounds.
Materials and methods. We analyzed the treatment of 769 combatants after gunshot wounds. The neuropathic component of pain was identified using the Douleur Neuropathique 4 questions. The statistical analysis was performed using the Shapiro-Wilk, Friedman, chi-square, and Bonferroni correction.
Results. The obtained data indicate that all combatants with chronic pain after gunshot wounds have a neuropathic component of pain (DN4 - from 4 to 5 points). Moreover, the results between the groups did not differ after 1 month - p=0.918, and after 3 months - 0.713, 6 months - p=0.824 and 12 months - p=0.911.
Conclusion. Combatants who sustained gunshot wounds have a high risk of chronic pain. It was found that the neuropathic component of pain is present in all patients in this category, so it may be one of the key components of such a high frequency of pain chronicity, which requires further research.
ANALYSIS OF PROVIDED MEDICAL SERVICES IN THE MEDICAL GUARANTEES PROGRAM PACKAGE «CHEMOTHERAPY TREATMENT AND MAINTENANCE OF ADULTS AND CHILDREN WITH ONCOLOGICAL DISEASES IN OUTPATIENT AND INPATIENT SETTINGS»
Authors: Husak N.B. , Zub V.О. , Kotuza A.S. 
Published: August 2023

Background. The approaches to the criteria for assigning a treated case/interaction to the "Oncology" package and the principles of their payment introduced in the National Health Service of Ukraine need to be optimized in order to prevent the risks of introducing inadequate rates, namely: not providing services for the amount specified in the rate and double/triple funding.
Aim: to investigate and identify the main defects and gaps in the existing U-Grouper rules regarding the assignment of a treated case/interaction to a package in the field of "Oncology" and to develop recommendations for improving the existing U-Grouper rules in this field based on the findings.
Materials and methods. A single descriptive-analytical study of the analysis of medical services provided in the oncology package 17 "Chemotherapy treatment and maintenance of adults and children with oncological diseases in outpatient and inpatient settings" for the first 8 months of 2022 in Ukraine was performed. Statistical methods, structural-logical analysis and systematic approach were used.
Results. The study found certain gaps in the coding of diagnoses under the diagnostically related group "R63 Chemotherapy", one of which is the incorrect coding of the main diagnosis during chemotherapy treatment, as only 20% of all Electronic Medical Records (EMRs) had the main diagnosis coded according to the Australian coding system (code Z51.1). Incorrect coding of oncological diseases was also detected, which may contribute to an increase in the payment of the case. Thus, in just 8 months of 2022, 19,368 interactions were registered, of which 35.7% (6,923) were without additional diagnoses, i.e., payment was made for such EMRs without clear criteria for the presence of a malignant neoplasm, which contradicts the requirements of the 17th package.
Conclusions. Based on the findings, it is proposed to make changes to the Medical Guarantees Program in the field of "Oncology" and to introduce automatic medical monitoring of EMRs, in which the main diagnosis of certain categories of classes C and D is coded, which will allow to bring the medical services provided to patients with oncohematological diseases into compliance with the rate.
SOME ASPECTS OF THE ETIOLOGY, PREVALENCE AND DIAGNOSIS OF THE TEMPOROMANDIBULAR JOINT DYSFUNCTION (A REVIEW)
Authors: Bezkorovaina L.P. , Zhehulovych Z.Ye. 
Published: August 2023

Background.Temporomandibular joint diseases (TMJ) occupy a special place among dental diseases due to the complexity of the clinical picture which often depends on within the professional competence of doctors of various specialties - otolaryngologists, neurologists, psychiatrists, rheumatologists, diseases whose complicate diagnosis and treatment. Painful TMJ dysfunction is a common disease that leads the patient to the dentist.
Aim: to analyze modern publications devoted to the problem of pain dysfunction of the temporomandibular joint in terms of causes and diagnostic methods related to practical dentistry.
Materials and methods. An analysis of data obtained during an information search in the online databases "PubMed", "SciELO", "Medcape" and "Science of Ukraine: access to knowledge" and official web-sites of Ukrainian education and scientific institutions was carried out using the keywords "pain dysfunction", "Costen's syndrome", "musculofascial syndrome", "temporomandibular joint".
Results. Today, TMJ dysfunction is an unsolved problem of practical dentistry which has a significant number of points of contact with other specialties. The pain and psycho-emotional component of this disease can be a significant problem for the patient and negatively affect his quality of life. The complex etio-pathogenesis of TMJ dysfunction and confusing classification of conditions leads to frequent assumptions of diagnostic and treatment mistakes of dentists and other specialists. Today, further development and improvement of diagnosis and treatment methods of patients with TMJ dysfunction, including the development and modification of diagnostic protocols and expanding indications for the use of modern highly informative diagnostic methods. Quite often the rehabilitation of such a patient requires a team approach and may last for years.
Conclusion. The organization of diagnosis, treatment and follow-up of patients with painful TMJ dysfunction needs further improvement and research.
Penentuan Konsentrasi Peg Untuk Seleksi Toleransi Kekeringan Pada Fase Benih Menggunakan 3 Varietas Cabai Lokal Sumatera Barat
Authors: Budiyanti Tri , Indriyani NLP , Kirana Rinda , Suliansyah Irfan , Hervani Dini 
Published: August 2023

Abstrak PEG sering dipergunakan untuk seleksi toleransi cekaman kekeringan pada fase perkecambahan benih. Selain itu PEG juga dapat berguna untuk osmoticum priming karena bersifat inert secara kimiawi dan tidak menimbulkan efek merusak pada embrio benih. Penelitian ini bertujuan untuk mengetahui konsentrasi kritis pemberian poly ethylene glycol (PEG 6000) yang menyebabkan penurunan perkecambahan benih 3 varietas cabai local Sumatera Barat sehingga dapat dipergunakan untk skrening toleransi kekeringan genotipe cabai pada fase perkecambahan. Penelitian ini menggunakan Rancangan Acak Lengkap 2 faktor. Faktor pertama adalah 3 varietas cabai yaitu Cabai Lontabar, Kopay dan Aka. Faktor kedua terdiri dari 6 perlakuan konsentrasi PEG yaitu 0%, 5%, 10%, 15%,20% dan 25 %. Hasil penelitian menunjukkan konsentrasi PEG 15% menyebabkan penurunan perkecambahan 3 varietas cabai asal Sumatera Barat. Pada konsentrasi 20% benih cabai sudah tidak berkecambah. Oleh karena itu untuk skrining toleransi kekeringan dapat menggunakan konsentrasi PEG 15% sehingga proses seleksi lebih efektif dan efisien. Kata kunci : Cabai, seleksi, PEG, toleran kekeringan
ANALISIS KERAGAMAN GEN PROLAKTIN (PRL) PADA ITIK PITALAH; ITIK LOKAL SUMATERA BARAT
Authors: Amelia Riska , Rusfidra Rusfidra , Subekti Kusnadidi , Arlina Firda , Husmaini Husmaini , Haryati Stefani Fitri 
Published: August 2023

AbstrakProlaktin merupakan hormon polipeptida yang disekresikan oleh kelenjar pituitary anterior dan secara spesifik kandidat gen yang mengontrol variasi jumlah produksi telur dengan reduksi biosintesis telur dalam beberapa periode mengeram. Tujuan penelitian ini adalah untuk menganalisis keragaman gen Prolaktin pada itik Pitalah. Ekstraksi yang dilakukan pada sampel darah 45 ekor itik Pitalah dengan menggunakan protocol G-spinTM Total DNA Extraction Mini Kit dari Intron Biotechnology. Selanjutnya diamplifikasi dengan menggunakan sepasang primer forward 5’- CTG CAT CTG TGG ACA TTG CT-3’ dan reverse 5’GAA GCA GGT TTG GGA GTA CG-3’ dengan target fragmen 496 bp dan disekuensing menggunakan jasa 1sr Base Singapore. Data hasil sekuensing dianalisis menggunakan Seqmen DNASTAR dan MEGA 11 dan menunjukkan 14 keragaman pada daerah ekson 4 dan parsial intron 3 dan 4 pada titik mutasi INDEL 3703A, INDEL3939A, C3974A, A4030G, A4038C, T4056C, G4061A, T4091G, T4094A, T4098C, G4102A, C4106A, A4107C dan C4154G. Keragaman gen Prolaktin bersifat polimorfik dengan frekuensi genotype tidak dalam keseimbangan Hardy-Weinberg. Kata Kunci: Prolaktin, Itik Pitalah, Keragaman, Mutasi, Mutasi, Sekuensing
Influence of Viral Marketing and Online Customer Review on Consumer Purchase Interest on Tiktok Social Media (Case Study on Mie Gacoan)
Authors: Sabillah Fauziah Zalza , Akbar Taufik , Latianingsih Nining 
Published: August 2023

Penelitian ini bertujuan untuk mengetahui dan menganalisis apakah terdapat pengaruh secara parsial dan simultan antara viral marketing dan online customer review terhadap minat beli konsumen. Selain itu, penelitian ini diharapkan dapat menjadi bahan pertimbangan bagi Mie Gacoan dalam memperhatikan viral marketing dan online customer review. Maka dari itu, minat beli konsumen akan meningkatkan. Penelitian ini termasuk dalam penelitian asosiatif kausal dengan menggunakan pendekatan kuantitatif. Penelitian ini menggunakan teknik non probability sampling dengan menggunakan metode purposive sampling. Jumlah sampel yang diambil sebanyak 100 responden. Pengujian instrument menggunakan uji validitas dan reliabilitas. Metode analisis data yang digunakan adalah regresi linear berganda, uji koefisien determinasi (R2), uji T dan uji F. Pengolahan data dalam penelitian ini dilakukan dengan menggunakan software SPSS 26 for windows. Berdasarkan hasil korelasi secara parsial variabel viral marketing memberikan pengaruh terhadap minat beli konsumen sebesar 64,16% dan variabel online customer review memberikan pengaruh terhadap minat beli konsumen sebesar 54,76%. Berdasarkan hasil analisis koefisien determinasi (R2), diperoleh sebesar 71,2% minat beli konsumen pada mie gacoan dipengaruhi oleh variabel independen yaitu viral marketing dan online customer review.
Kata Kunci : Viral Marketing, Online Customer Review, Minat Beli Konsumen
IMPLEMENTASI DATA MINING KLASIFIKASI KEPRIBADIAN ORANG-ORANG MENGGUNAKAN ALGORITMA NAÏVE BAYES
Authors: Revata Sylvain , Rino  
Published: August 2023

Kepribadian atau personality berasal dari kata Persona, kata yang merujuk pada kedok atau topeng. Persona ini memiliki arti tentang bagaimana seseorang tampak di hadapan orang lain. Secara umum, kepribadian pada seseorang itu dapat di lihat bagaimana mereka tampil dan memberikan kesan terhadap orang-orang yang ada disekitarnya. Oleh karena itu ada banyak tipe kepribadian pada seseorang, dari tipe-tipe yang ada tersebut sulit untuk ditebak pada seseorang. Karena harus dapat mengetahui ciri-ciri yang ada dalam tipe-tipe kepribadiannya. Maka dengan itu dibuatlah aplikasi data mining untuk memprediksi tipe kepribadian seseorang. Saat ini algoritma naïve bayes klasifikasi adalah salah satu metode yang cukup efektif untuk digunakan dalam memprediksi suatu peluang di masa depan dengan menggunakan data-data yang ada sebelumnya. Hal ini disebabkan karena algoritma naïve bayes merupakan metode klasifikasi yang mudah dipahami oleh perancang sistem dan pengguna sistem. Tujuan pembuatan aplikasi data mining ini adalah untuk membantu orang-orang dalam mengetahui tipe kepribadian apa yang dimilikinya.
An Autoencoder-Based Deep Learning Classifier for Efficient Diagnosis of Autism
Authors: Sewani Harshini 
Published: August 2023

<p>Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by a lack of social communication and social interaction. Autism is a mental disorder that is investigated by social and computational intelligence scientists utilizing advanced technologies such as machine learning models to enhance the ability of clinicians to provide robust diagnosis and prognosis of Autism. However, with dynamic changes in Autism behavior patterns, the quality and accuracy of these models have become a great challenge for clinical practitioners. We have applied a deep neural network learning on a large brain image dataset obtained from ABIDE (Autism Brain Imaging Data Exchange) to identify ASD patients. Our deep learning model combines both unsupervised neural network learning, Autoencoder, and supervised deep learning using Convolutional Neural Network. Our proposed algorithm outperforms individual-based classifiers measured by various validations and assessment measures. </p>
Donor Darah dalam Rangka Dies Natalis Fakultas Kedokteran Universitas Khairun
Authors: Nur Amran , Fiskia Ermalyanti 
Published: August 2023

Donor darah adalah merupakan suatu proses pemberian darah secara sukarela untuk tujuan transfusi darah bagi orang lain yang membutuhkan. Transfusi darah adalah kegiatan medis memberikan darah kepada seorang penderita yang darahnya telah disediakan dalam kantong plasti. Darah merupakan salah satu bagian terpenting dalam tubuh manusia dikarenakan darah memiliki fungsi untuk mengedarkan sari makanan, mengangkut oksigen, mengedarkan hormon, dan lain-lain. Kekurangan jumlah darah di dalam tubuh akan berakibat pada kerusakan jaringan dan kegagalan fungsi organ-organ vital yang dapat menyebabkan kematian. Seiring dengan pertambahan penduduk maka kebutuhan cadangan darah terus meningkat. Akan tetapi, ketimpangan antara jumlah pasokan dengan permintaan darah di beberapa Unit transfusi darah (UTD) sering terjadi sehingga menyebabkan kelangkaan darah di Unit Transfusi Darah (UTD).salah satu upaya agar persediaan darah tetap mencukupi salah satunya melakukan Â Kegiatan sosial donor darah sekaligus di rangkaikan dengan dies Natalis Fakuktas Kedokteran Universitas Khairun yang bekerjasama dengan Unit Transfusi Darah (UTD) Palang Merah Iindonesia (PMI) Kota Ternate.
ESBL and carbapenemase-producing Enterobacteriaceae in infectious pleural effusions: current epidemiology at Hôpital du Mali
Authors: Kalambry Aimé Césaire , Potindji Tchamou Malraux Fleury , Guindo Ibrehima , Kassogué Ambara , Drame Boubacar Sidiki Ibrahim , Togo Seydou , Yena Sadio , Doumbia Seydou , Diakite Mahamadou 
Published: August 2023

Background: Antimicrobial resistance (AMR) is a global health concern, with extended-spectrum β-lactamases (ESBLs) and carbapenemases being major contributors. Pleural infection (PI) is a severe condition in West Africa, complicated by AMR. This study aimed to investigate the prevalence and molecular characteristics of ESBL and carbapenemase-producing enterobacteria in pleural effusions in Mali.
Materials and methods: Pleural fluid samples from 526 patients with pleuritis were analyzed. Enterobacterial species were isolated and identified, and the prevalence of resistance genes (blaOXA-48, blaNDM-1, blaKPC, blaTEM, blaSHV) and virulence factors was determined.
Results: Among the patients, 110 were diagnosed with enterobacterial pleuritis. Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis were the main pathogens identified. Resistance to β-lactams and cephalosporins was high, while carbapenems showed good activity. ESBL production was detected in 33.6% of isolates, with blaTEM being the most common gene. Carbapenemase gene (blaNDM-1) was found in three isolates.
Conclusion: The study highlights the high prevalence of multidrug-resistant bacteria and the need for appropriate antibiotic selection based on local resistance patterns. Understanding the molecular characteristics of resistance is crucial for optimizing patient care and developing effective therapeutic strategies. Further research is needed to monitor and control AMR in PIs in Mali.
Transforming Personal Death into Public Martyrdom
Authors: Enstedt Daniel , Giubergia Giulia 
Published: August 2023

Abstract
This article examines ways to analyze and understand the social and cultural transformation that occurred after the 2011 uprising in downtown Cairo. We argue for a cultural sociological perspective using a renewed version of the concept “the sacred” for analysis. Visual material – graffiti and murals on the walls of Cairo – is discussed in relation to the process of transforming the death of an individual into collective martyrdom. The role of social media, public rituals, and celebrations in the events in Tahrir Square is also discussed. This article shows how the process of sacralization follows a recurring pattern in which individual deaths transmigrate into new collective, ritualized memories through the use of aesthetics in social media and on murals. Using different types of field-based and online material, this article argues for a cultural sociological perspective whereby individual death also can be understood on a more general level as a constituent part of the existing and contested societal order. The emphasis on a processual view of social and cultural transformation is equally important. This view includes a dialectical perspective, which together with an awareness of spatiality, materiality, new media, and embodiment, is essential for an understanding of what happened in downtown Cairo after the uprising in 2011.
Laser microdissection, proteomics, and multiplex immunohistochemistry: a bumpy ride into the study of paraffin-embedded fetal and pediatric lung tissues
Authors: Cardoso dos Santos Luis M. , Avila Yannick , Schvartz Domitille , Rougemont Anne-Laure , Bochaton-Piallat Marie-Luce , Ruchonnet-Metrailler Isabelle 
Published: August 2023

BackgroundKnowledge about lung development or lung disease is mainly derived from data extrapolated from mouse models. This has obvious drawbacks in developmental diseases, particularly due to species differences. Our objective is to describe the development of complementary analysis methods that will allow a better understanding of the molecular mechanisms involved in the pathogenesis of rare congenital diseases.MethodsParaffin-embedded human pediatric and fetal lung samples were laser microdissected to enrich different lung regions, namely, bronchioli or alveoli. These samples were analyzed by data-independent acquisition-based quantitative proteomics, and the lung structures were subsequently compared. To confirm the proteomic data, we employed an optimized Sequential ImmunoPeroxidase Labeling and Erasing (SIMPLE) staining for specific proteins of interest.ResultsBy quantitative proteomics, we identified typical pulmonary proteins from being differentially expressed in different regions. While the receptor for advanced glycation end products (RAGE) and the surfactant protein C (SFTPC) were downregulated, tubulin beta 4B (TUBB4B) was upregulated in bronchioli, compared to alveoli. In fetal tissues, CD31 was downregulated in fetal bronchioli compared to canaliculi. Moreover, we confirmed their presence using SIMPLE staining. Some expected proteins did not show up in the proteomic data, such as SOX-9, which was only detected by means of immunohistochemistry in the SIMPLE analysis.ConclusionOur data underline the robustness and applicability of this type of experimental approach, especially for rare paraffin-embedded tissue samples. It also strengthens the importance of these methods for future studies, particularly when considering developmental lung diseases, such as congenital lung anomalies.
The association between patellofemoral grind and synovitis in knee osteoarthritis: data from the osteoarthritis initiative
Authors: Deng Hui , Wu Yongzhong , Fan Zaiwei , Tang Wubing , Tao Jun 
Published: August 2023

ObjectivePatellofemoral grind refers to the tender behind the knee cap while contracting the quadriceps muscle during the patellar grind test. The present investigation aims to elucidate the association between patellofemoral grind and synovitis in the knee osteoarthritis (KOA).MethodA total of 1,119 knees with complete patellofemoral grind and synovitis assessment records from the Osteoarthritis Initiative (OAI) were investigated in this study. The Magnetic Resonance Imaging at baseline, 12 months, and 24 months of follow-up were employed to evaluate synovitis. Frequent patellofemoral grind was operationally defined as occurring more than twice at three different time points. In addition, a sensitivity stratification was conducted to examine gender differences.ResultsThe study participants had an average age of 61 years, with 62.4% being female. The findings revealed that baseline patellofemoral grind was significantly associated with changes in synovitis at follow-up (odds ratio [OR]: 1.44, confidence interval [CI]: 1.04–1.98) and was also linked to synovitis worsening over 24 months (OR: 1.67, CI: 1.13–2.46) in all subjects. For the subjects with frequent patellofemoral grind, this correlation was more significant (OR: 1.50, CI: 1.03–2.16; OR: 1.71, CI: 1.09–2.67). In the context of sensitivity stratification, it was observed that the baseline and frequent patellofemoral grind in females exhibited a significant correlation with synovitis. However, no significant correlation was found in males.ConclusionPatellofemoral grind may serve as a potential risk factor of synovitis in knee osteoarthritis, particularly among female patients, and thus, necessitates close monitoring and management by clinical physicians.
Association between levels of IgG antibodies from vaccines and Omicron symptomatic infection among children and adolescents in China
Authors: Chen Xinying , Hong Junbin , Deng Lijun , Weng Heng , Huang Teng , Wang Li , Ou Aihua , Li Yuxia , Yu Bo , Guo Jianwen , Yang Jinghua 
Published: August 2023

BackgroundMeasurements of IgG antibodies to wild-type SARS-CoV-2 antigens can assess vaccine efficacy, but the absolute risk of Omicron symptomatic infection at different IgG levels for children and adolescents remains uncertain, as well as the minimum effective antibody level. We sought to determine the relationship between the tertiles of IgG antibodies to wild-type SARS-CoV-2 antigens and children with symptomatic infection of the pandemic and duration to negative conversion in China for the first time.MethodsA retrospective study was conducted, including 168 participants under 18 years old from the No.2 People’s Hospital of Lanzhou, China, diagnosed with Omicron variant BA.2.38 between July 8, 2022, and August 2, 2022. We calculated odds ratios (OR) in univariate and multivariate regression to assess the association of symptomatic infection with the tertiles of IgG, respectively. Kaplan–Meier curves and Cox proportional hazards regression were used to evaluate the relationship between IgG level and negative conversion time.ResultsThe average age of the 168 children included in this study was 7.2 (4.7) years old, 133 (79.2%) were symptomatic patients, and the average negative conversion time was 12.2 (3.5) days. The participants with high IgG levels were less likely to become symptomatic, had a shorter turnaround time, and had higher values of IgM and nucleic acid CT. Compared to those with the lowest tertile of IgG, patients with the highest tertile had a 91% lower risk of developing a symptomatic infection after fully adjusting for confounders (OR = 0.09, 95% CI, 0.02-0.36, p = 0.001). There’s no robust relationship between IgG level and negative conversion time in multivariate Cox regression.ConclusionThe risk of developing a symptomatic infection can be predicted independently by tertiles of IgG antibodies to wild-type SARS-CoV-2 antigens. High IgG levels can inhibit viral replication, vastly reduce the risk of symptomatic infections and promote a virus-negative conversion, especially when IgG quantitative detection was ≥3.44 S/CO, a potential threshold for protection and booster strategy in the future. More data and research are needed in the future to validate the predictive models.