bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stabilization of Inorganic Perovskite Solar Cells with a 2D Dion–Jacobson Passivating Layer
Authors: Wu Luyan , Li Guixiang , Prashanthan Karunanantharajah , Musiienko Artem , Li Jinzhao , Gries Thomas W. , Zhang Hao , Köbler Hans , Janasik Patryk , Appiah Augustine N. S. , Paramasivam Gopinath , Sun Tianxiao , Li Meng , Marongiu Daniela , Saba Michele , Abate Antonio 
Published: July 2023

AbstractInorganic metal halide perovskites such as CsPbI3 are promising for high‐performance, reproducible, and robust solar cells. However, inorganic perovskites are sensitive to humidity, which causes the transformation from the black phase to the yellow δ, non‐perovskite phase. Such phase instability has been a significant challenge to long‐term operational stability. Here, a surface dimensionality reduction strategy is reported, using 2‐(4‐aminophenyl)ethylamine cation to construct a Dion–Jacobson 2D phase that covers the surface of the 3D inorganic perovskite structure. The Dion–Jacobson layer mainly grows at the grain boundaries of the perovskite, effectively passivating surface defects and providing favourable interfacial charge transfer. The resulting inorganic perovskite films exhibit excellent humidity resistance when submerged in an aqueous solution (isopropanol:water = 4:1 v/v) and exposed to a 50% humidity air atmosphere. The Dion–Jacobson 2D/3D inorganic perovskite solar cell (PSC) achieves a power conversion efficiency (PCE) of 19.5% with a Voc of 1.197 eV. It retains 83% of its initial PCE after 1260 h of maximum power point tracking under 1.2 sun illumination. The work demonstrates an effective way for stabilizing efficient inorganic perovskite solar cells.
Lentil nitrogen fixation response to fertilizer and inoculant in the northern Great Plains
Authors: Baber Kaleb , Jones Clain , Miller Perry , Lamb Peggy , Atencio Sydney 
Published: July 2023

AbstractLentil (Lens culinaris Medikus) production in the semiarid northern Great Plains of the United States has increased dramatically over the past two decades. Lentil in rotation provides agroecosystem benefits of more efficient water use, pest cycle disruption, and biological nitrogen (N) fixation. Increasing N fixation could alleviate soil acidification and groundwater impairment, decrease N fertilizer costs, and increase lentil seed yield. Despite widespread farmer adoption of lentil in the region, little is known about the benefits of fertilizer or inoculant type on N fixation. The aim of this study was to determine how nutrients (potassium (K), sulfur (S), and foliar‐applied micronutrients) and rhizobial inoculant types (seed‐coat powder and granular) influence N fixation of lentil. The study was conducted at two field sites in Montana from 2019 to 2021. Fixed N amounts were calculated using both an N difference approach and 15N natural abundance method. N fixation was highly responsive to climatic conditions and soil characteristics. The amount of N fixed did not respond to K fertilization, likely because soil test K levels were sufficient. In a moderately dry year at a site with low soil sulfate‐S, fertilizer application of 5.6 kg S ha−1 increased N fixed by 40%. Inoculated lentil fixed more N than uninoculated lentil in two site‐years, but there were no differences in N fixed between inoculant types. Inoculation response was not related to field cropping histories with legumes. The study shows that S fertilization and rhizobial inoculation have potential to increase lentil N fixation amounts in the northern Great Plains.
Single‐agent lenalidomide maintenance after upfront autologous stem cell transplant for newly diagnosed multiple myeloma: The MD Anderson experience
Authors: Pasvolsky Oren , Milton Denái R. , Masood Adeel , Sami Sophiya S. , Tanner Mark R. , Bashir Qaiser , Srour Samer , Saini Neeraj , Lin Paul , Ramdial Jeremy , Nieto Yago , Saeed Arsalan , Lee Hans C. , Patel Krina K. , Kebriaei Partow , Thomas Sheeba K. , Weber Donna M. , Orlowski Robert Z. , Shpall Elizabeth J. , Champlin Richard E. , Qazilbash Muzaffar H. 
Published: July 2023

AbstractThe optimal duration of lenalidomide (Len) maintenance for patients with multiple myeloma (MM) after autologous stem cell transplantation (autoHCT) is unknown. We conducted a retrospective single‐center analysis of adult MM patients that received upfront autoHCT between 2005 and 2021, followed by single‐agent Len maintenance. A total of 1167 patients were included with a median age of 61.4 (range 25.4–82.3) years, and high‐risk chromosomal abnormalities in 19%. Median duration of maintenance was 22.3 (range 0.03–139.6) months. After a median follow‐up of 47.9 (range 2.9–171.7) months, median PFS and OS for the entire cohort were 56.6 (95% CI 48.2–61.4) months and 111.3 (95% CI 101.7–121.5) months, respectively. In MVA, high‐risk cytogenetics was associated with a worse PFS (HR 1.91) and OS (HR 1.73) (p < .001 for both). Use of KRD induction and achievement of MRD‐negative ≥ VGPR before autoHCT were associated with an improved PFS (HR 0.53 and HR 0.57, respectively; p < .001 for both). Longer maintenance duration, even with a 5‐year cutoff, was associated with superior PFS and OS (HR 0.17 and 0.12, respectively; p < .001 for both). A total of 106 patients (9%) developed a second primary malignancy (SPM), mostly solid tumors (39%) and myeloid malignancies (30%). Longer maintenance duration was associated with a higher risk of SPM, reaching statistical significance after >2 years (odds ratio 2.25; p < .001). In conclusion, outcomes with Len maintenance were comparable to those reported in large clinical trials. Longer duration of maintenance, even beyond 5 years, was associated with improved survival.
Compound heterozygous variants in MAPK8IP3 were detected in severe congenital hypotonia mimicking lethal spinal muscular atrophy
Authors: Kárteszi Judit , Ziegler Alban , Tihanyi Mariann , Elmont Beatrix , Zhang Yuebo , Patócs Barbara , Molnár Mária Judit , Méhes Gábor , Wells Kirsty , Jakus Rita , Bessenyei Beáta , Ranatunga Wasantha , Morava Éva 
Published: July 2023

AbstractMitogen‐activated protein kinase 8‐interacting protein 3 gene (MAPK8IP3) encodes the c‐Jun‐amino‐terminal kinase‐interacting protein 3 (JIP3) and is involved in retrograde axonal transport. Heterozygous de novo pathogenic variants in MAPK8IP3 result in a neurodevelopmental disorder with or without brain abnormalities and possible axonal peripheral neuropathy. Whole‐exome sequencing was performed on an individual presenting with severe congenital muscle hypotonia of neuronal origin mimicking lethal spinal muscular atrophy. Compound heterozygous rare variants (a splice and a missense) were detected in MAPK8IP3, inherited from the healthy parents. Western blot analysis in a muscle biopsy sample showed a more than 60% decrease in JIP3 expression. Here, we suggest a novel autosomal recessive phenotype of a lower motor neuron disease caused by JIP3 deficiency.
Postnasal drip and chronic cough in patients with chronic rhinitis treated with temperature‐controlled radiofrequency neurolysis
Authors: Gorelik Daniel , Ahmad Jumah G. , Razmi Samuel E. , Takashima Masayoshi , Yiu Yin , Thekdi Apurva , Ramanathan Murugappan , Dhanda Aatin K. , Yim Michael T. , Ahmed Omar G. 
Published: July 2023

AbstractObjectiveTo evaluate the contribution of postnasal drip (PND) and chronic cough (CC) to symptoms of patients with chronic rhinitis treated with temperature‐controlled radiofrequency (TCRF) neurolysis of the posterior nasal nerve (PNN), and correlate PND and CC scores with components of the reflective total nasal symptom score (rTNSS).MethodsPooled data from three prospective studies: two single‐arm studies and the index active treatment arm of a randomized controlled trial. Adult patients with baseline rTNSS ≥6 were treated with TCRF neurolysis at nonoverlapping regions of the PNN. PND and CC symptoms were evaluated on a 0 (none) to 3 (severe) scale.ResultsData from 228 patients (57.9% women, 42.1% men) were included. The mean baseline rTNSS was 8.1 (95% confidence interval [CI], 7.8–8.3), which decreased to 3.2 (95% CI, 2.9–3.5) at 6 months. At baseline, 97.4% of patients had PND and 80.3% had CC. Median baseline PND and CC symptom scores were 3 (interquartile range [IQR], 2–3) and 2 (IQR, 1–2), respectively. At 6 months, this decreased to 1 (IQR, 0–2) and 0 (IQR, 0–1), respectively, showing significant improvement from baseline (both p < 0.001). Spearman correlation coefficients with components of rTNSS (rhinorrhea, congestion, itching, sneezing) were 0.16 to 0.22 for CC and 0.19 to 0.46 for PND, indicating only a weak to moderate correlation.ConclusionPND and CC contribute to the symptomatology of chronic rhinitis and are significantly improved after TCRF neurolysis of the PNN. The inclusion of PND and CC symptoms in a chronic rhinitis assessment instrument could provide important additional information for the characterization of the disease state and outcomes after any therapeutic treatment.
Association of obesity paradox with prognosis of veno‐venous‐extracorporeal membrane oxygenation in patients with coronavirus disease 2019
Authors: Honzawa Hiroshi , Taniguchi Hayato , Ogawa Fumihiro , Oi Yasufumi , Abe Takeru , Takeuchi Ichiro 
Published: July 2023

AbstractAimAlthough the obesity paradox is known for various diseases, including cancer and acute respiratory distress syndrome, little is known about veno‐venous extracorporeal membrane oxygenation (VV‐ECMO) in patients with coronavirus disease 2019 (COVID‐19). In this study, we aimed to investigate the association between body mass index (BMI) and prognosis in critical patients with COVID‐19 requiring VV‐ECMO.MethodsWe conducted a retrospective observational single‐center study at Yokohama City University Civic General Medical Center between March 2020 and October 2021. Participants were patients with COVID‐19 who required VV‐ECMO. They were classified into two groups: BMI ≤30 kg/m2 and >30 kg/m2.ResultsIn total, 23 patients were included in the analysis, with a median BMI of 28.7 kg/m2. Overall, 22 patients were successfully weaned from the ECMO. When comparing the two groups, there was a trend toward fewer days from onset to ECMO induction in the BMI >30 kg/m2 group. Moreover, the two groups had a similar prognosis. There were no statistically significant differences in the number of days from onset to hospitalization or the duration of ECMO induction between the groups.ConclusionVV‐ECMO induction for patients with COVID‐19 may lead to earlier indications in patients with BMI >30 kg/m2 than in those with BMI ≤30 kg/m2.
Enhanced Spatial Charge Separation in a Niobium and Tantalum Nitride Core‐Shell Photoanode: In Situ Interface Bonding for Efficient Solar Water Splitting
Authors: Zhang Beibei , Fan Zeyu , Chen Yutao , Feng Chao , Li Shulong , Li Yanbo 
Published: July 2023

AbstractTantalum nitride (Ta3N5) has emerged as a promising photoanode material for photoelectrochemical (PEC) water splitting. However, the inefficient electron‐hole separation remains a bottleneck that impedes its solar‐to‐hydrogen conversion efficiency. Herein, we demonstrate that a core–shell nanoarray photoanode of NbNx‐nanorod@Ta3N5 ultrathin layer enhances light harvesting and forms a spatial charge‐transfer channel, which leads to the efficient generation and extraction of charge carriers. Consequently, an impressive photocurrent density of 7 mA cm−2 at 1.23 VRHE is obtained with an ultrathin Ta3N5 shell thickness of less than 30 nm, accompanied by excellent stability and a low onset potential (0.46 VRHE). Mechanistic studies reveal the enhanced performance is attributed to the high‐conductivity NbNx core, high‐crystalline Ta3N5 mono‐grain shell, and the intimate Ta−N−Nb interface bonds, which accelerate the charge‐separation capability of the core–shell photoanode. This study demonstrates the key roles of nanostructure design in improving the efficiency of PEC devices.
Chiral PSiSi‐Ligand Enabled Iridium‐Catalyzed Atroposelective Intermolecular C−H Silylation
Authors: Yang Bo , Gao Jihui , Tan Xingfa , Ge Yicong , He Chuan 
Published: July 2023

AbstractCatalytic enantioselective intermolecular C−H silylation offers an efficient approach for the rapid construction of chiral organosilicon compounds, but remains a significant challenge. Herein, a new type of chiral silyl ligand is developed, which enables the first iridium‐catalyzed atroposelective intermolecular C−H silylation reaction of 2‐arylisoquinolines. This protocol features mild reaction conditions, high atom economy, and remarkable yield with excellent stereoselectivity (up to 99 % yield, 99 % ee), delivering enantioenriched axially chiral silane platform molecules with facile convertibility. Key to the success of this unprecedented transformation relies on a novel chiral PSiSi‐ligand, which facilitates the intermolecular C−H silylation process with perfect chem‐, regio‐ and stereo‐control via a multi‐coordinated silyl iridium complex.
Electrical Circuit Modeling of Nanofluidic Systems
Authors: Sebastian John , Green Yoav 
Published: July 2023

AbstractNanofluidic systems exhibit transport characteristics that have made technological marvels such as desalination and energy harvesting possible by virtue of their ability to influence small currents due to selective ion transport. Traditionally, these applications have relied on nanoporous membranes whose complicated geometry impedes a comprehensive understanding of the underlying physics. To bypass the associated difficulties, we consider the simpler nanochannel array and elucidate the effects of interchannel interactions on the Ohmic response. It is demonstrated that a nanochannel array is equivalent to an array of mutually independent but identical unit‐cells whereby the array can be represented by an equivalent electrical circuit of resistances connected in a parallel configuration. The model is validated using numerical simulations and experiments. The approach to modeling nanofluidic systems by their equivalent electrical circuit provides an invaluable tool for analyzing and interpreting experimental measurements.
Pyrolysis of Mixed Date Stones and Pistachio Shells: Identification of Bio‐Oil and Utilization of Bio‐Char as Activated Carbon Precursor
Authors: Ibrahim Ass. Lecturer Shaimaa Y. , Mahmood Saad F. , Younis Ass. Lecturer Shahla A. , Fadhil Abdelrahman B. 
Published: July 2023

AbstractThermal pyrolysis of mixed date stones and pistachio shells in a semi‐batch reactor was addressed in this study. The highest yield of liquids (51.20 %) was produced at 500 °C, 90 min, 20 °C/min heating rate, and 50 mesh particle size. Under these conditions, yield of liquid from date stones and pistachio shells separately was 49.12 % and 47.67 %, respectively. The FT‐IR results confirmed the presence of multiple oxygen‐containing compounds in the bio‐oil. Results from GC–MS declared that it was predominately composed of acids (57.57 %), esters (21.35 %), phenols (4.63 5), and alcohols (3.49 5). The obtained biochar was transformed into activated carbon (AC) by the optimized ZnCl2 activation method. The ideal AC was synthesized at 600 °C for 60 min using a 2 : 1 ZnCl2: biochar impregnation ratio. FESEM and XRD measurements showed that the AC was amorphous. The prepared AC was effective in eliminating dibenzothiophene (DBT) from model fuel (200 ppm DBT/hexane) with a maximum performance 95.26 % at 40 °C for 1h using 0.35 g of the AC. The exhausted AC was regenerated and reutilized 4 times, and removal efficiency reached 88.23 % in the 4th cycle under ideal working conditions.
Prognostic role of CA‐125 in patients undergoing transcatheter aortic valve replacement: A systematic review and meta‐analysis
Authors: Diaz‐Arocutipa Carlos , Saucedo‐Chinchay Jose , Mamas Mamas A. 
Published: July 2023

AbstractTranscatheter aortic valve replacement (TAVR) has become a widely used therapy for patients with severe aortic stenosis. Carbohydrate antigen 125 (CA‐125) is a promising biomarker in some cardiovascular diseases. This systematic review aims to assess the prognostic role of CA‐125 in patients undergoing TAVR. We searched electronic databases from inception to March 2023 to include cohort studies evaluating the association between preprocedural CA‐125 levels and mortality or heart failure (HF) readmission at 12 months in patients undergoing TAVR. We pooled crude (cHR) and adjusted hazard ratios (aHR) with their 95% confidence interval (CI) using a random‐effects model. The risk of bias was evaluated using the QUIPS tool. The certainty of the evidence was assessed using the GRADE approach. We included five cohort studies involving 1594 patients. Higher levels of CA‐125 were significantly associated with an increased risk of mortality or HF readmission using crude (cHR 2.79, 95% CI 1.45–5.36, I2 =  72%) and adjusted (aHR 3.27, 95% CI 2.07–5.18, I2 =  0%, high certainty) effect estimates compared with lower levels. Similarly, there was also associated with increased mortality using crude (cHR 2.68, 95% CI 1.99–3.60, I2 =  0%) and adjusted (aHR 2.17, 95% CI 1.54–3.07, I2 =  0%, high certainty) effect estimates. The risk of bias varied between low to moderate across studies. Our meta‐analysis suggests that CA‐125 has incremental prognostic value in patients undergoing TAVR. Further studies are needed to determine the clinical utility of CA‐125 in guiding treatment decisions in this population.
Enhancing sustainable development through effective disclosure: Corporate environmental performance and readability
Authors: Zhou Kuo , Jin Xianghui , Li Xinru , Tao Yunqing 
Published: July 2023

AbstractAlthough previous studies have explored the effect of corporate environmental performance on the content of environmental disclosure, little research has investigated its impact on the textual characteristics of environmental disclosure, particularly readability. This study constructs three measures of corporate environmental disclosure (CED) readability and examines the effect of corporate environmental performance on it. Using panel data from Chinese listed firms in heavy pollution industries during the period from 2008 to 2019, we find a robust positive association between corporate environmental performance and CED readability. Furthermore, we find that this association is stronger in firms with worse earning performance, stricter regional environmental regulation, or more media attention. Our analyses also reveal a positive association between CED readability and stock price crash risk. Overall, our study contributes to the research on corporate environmental performance and environmental disclosure readability and has important implications for optimizing the regulations of environmental disclosure. Our study contributes to the literature on corporate environmental performance and environmental disclosure and also provides important theoretical and practical implications for improving corporate environmental disclosure regulation.
Comparative expression of TRPS1, GATA3, SOX10, mammaglobin, and GCDFP‐15 in effusion specimens with breast carcinoma
Authors: Bradt Ashley , Jing Xin , Smola Brian S. , Lew Madelyn 
Published: July 2023

AbstractBackgroundTraditional immunohistochemistry (IHC) for breast carcinomas has shown low detection rates of metastatic breast carcinoma (MBC) in effusions. Although GATA3 has enhanced diagnostic accuracy in this realm, its limited utility in detecting triple‐negative breast carcinoma (TNBC) has been highlighted. TRPS1 has been introduced as a potentially sensitive and specific marker in detecting MBC on histologic samples. We investigate the utility of TRPS1 as a marker for MBC in effusion specimens and compare its performance to SOX10, GATA3, mammaglobin (MG), and GCDFP‐15.MethodsA database search identified malignant effusions involved by MBC between 2013 and 2021. Cases from unique patients with sufficient cellularity were evaluated for TRPS1, GATA3, SOX10, MG, and GCDFP‐15 IHC. The intensity and extent of tumor cells (TC) were scored by two pathologists. Any discrepancies were jointly reviewed for consensus.ResultsGATA3 showed the highest rate of positivity (98.2%), followed by TRPS1 (89.5%), MG (43.9%), GCDFP‐15 (21.1%), and SOX10 (3.5%). All GATA3‐positive cases showed intermediate to high expression. Comparatively, TRPS1 showed more variability in staining extent and intensity. In 13 (22.8%) cases, TRPS1 showed extensive background staining of inflammatory and mesothelial cells. Of six TNBCs, GATA3, and TRPS1 were positive in six (100%) and four (66.7%) cases, respectively.ConclusionsWhile TRPS1 shows a lower detection rate for MBC than GATA‐3, using a combination of these markers can enhance effusion cytology's performance in detecting MBC. However, variability in TRPS1 staining intensity and high background TRPS1 staining of inflammatory and mesothelial cells can increase difficulty in its evaluation.
Dabigatran‐induced esophagitis with full circumferential blue pigmentation
Authors: Araki Tomonori , Hayashi Kohei , Sonoda Yuki , Honda Takuya , Imamura Yoshifumi , Koide Yuji , Hamada Hisayuki , Nakao Kazuhiko 
Published: July 2023

AbstractDabigatran is a useful and widely used drug for stroke prevention in patients with atrial fibrillation. However, it has been reported to cause esophagitis. Herein, we report the case of a 77‐year‐old man with dabigatran‐induced esophagitis with blue pigmentation, which is known to be a rare adverse effect. The patient presented to our hospital with a tightness of the chest and anorexia. Computed tomography revealed a thickening of the entire esophageal wall, with an upper esophageal predominance. Esophagogastroduodenoscopy was performed, which showed that the cervical and upper thoracic esophagus had blue pigmentation with edematous changes, partial narrowing, and longitudinal sloping. We replaced dabigatran with edoxaban, a similar anticoagulation medication. The patient was closely monitored for 1 month after switching to edoxaban. The follow‐up esophagogastroduodenoscopy showed marked improvements, revealing resolution of the bluish discoloration and edematous changes, and the patient's complaints regarding the tightness of the chest and anorexia were also resolved. It is important to recognize that such side effects can occur with dabigatran, a drug that is frequently used in daily practice. Considering the fact that strong edematous changes can cause indigo carmine pigmentation associated with dabigatran stagnation, we recommend switching to another anticoagulant if esophagitis occurs during dabigatran administration.
Polyoxometalate‐Incorporated CuI‐Resorcin[4]arene Metal‐Organic Complexes as Heterogeneous Catalysts for Catalytic Oxidation of Mustard Gas Simulant
Authors: Yu Ming‐Yue , Liu Jin‐Hua , Liu Fang‐Wang , Zou Fang , Zhang Li , Gao Qing‐Ping , Ren Xiao‐Yan , Zhang Qian , Liu Shi‐Zhong , Dong Chun‐Peng , Guo Ting‐Ting , Ma Tian‐Fang , Pei Wen‐Yuan 
Published: July 2023

AbstractExploring efficient heterogeneous catalysts for catalytic oxidation of chemical warfare agents (CWAs) is highly desired. As a class of discrete anionic metal oxide clusters, polyoxometalates (POMs) provide abundant catalytic active sites, thus resulting their rich redox properties. Here, a family of known POM‐incorporated CuI‐resorcin[4]arene metal‐organic complexes, namely, [Cu4(TPTR4A)2][PW12O40](OH) ⋅ 0.5DMA ⋅ 5H2O (Cu‐PW), [Cu4(TPTR4 A)2][PMo12O40](OH) ⋅ 2DMA ⋅ H2O (Cu‐PMo) and [Cu4(TPTR4A)2][SiW12O40] ⋅ 2.5DMA (Cu‐SiW) were utilized as catalysts to promote the oxidation of 2‐chloroethyl ethyl sulfide (CEES). Strikingly, compared to the novel compound [Cu3Cl6(TPTR4A)(DMA)] ⋅ CH3CH2OH (defined as Cu‐T), the three complexes exhibited excellent stability, indicating that the integration of POMs and metal–organic units could improve the stability of the compounds. Moreover, Cu‐PMo and Cu‐PW showed higher activities for the catalytic oxidation of CEES to CEESO with selectivities both of 99 %.