bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quantitative comparison of spark plasma's influence on parameters affecting rejuvenation of the skin at two different voltages
Authors: Ghasemi Erfan , Nilforoushzadeh Mohammad Ali , Khani Mohammadreza , Amirkhani Mohammad Amir , Nouri Maryam , Charipoor Parisa , Shokri Babak 
Published: August 2023

Abstract
The skin is the body's largest organ and protects against mechanical, thermal, and physical harm. However, the skin's function and appearance decrease visibly with age due to repeated exposure to adverse environmental impacts such as UV rays and toxic substances and the development of oxidative stress in aging. During aging, these factors cause phenotypic changes in the skin, such as wrinkles, pigmentation, loss of elasticity, and moisture. SPARK plasma has been found in studies to preserve skin against aging effectively. The effects of two separate spark plasma device modes with voltages of 3.44 and 4.88 kV on skin health, including pigmentation, skin firmness, elasticity, and moisture loss, were studied using the MPA9 multifunctional skin tester in this study. In addition, utilizing ultrasound, the effectiveness of two plasma modes on skin density and thickness was examined. The findings of this study suggest that spark plasma may slow the skin's aging process by enhancing its elasticity, density, and thickness. However, there were no difficulties or scars at the treatment location at the end of this study, indicating that Spark plasma can be utilized as a new way to delay the aging process.
Study on the influence of bond length on the bond properties of CFRP-concrete interface under Sulfate environment
Authors: Cheng YANG , ZHANG Shize , ZHANG Jiyuan 
Published: August 2023

Abstract
Sulfate attack is an important factor in the degradation of CFRP-concrete interface properties. The sulfate test was simulated by the accelerated dry-wet cycle test to study the effect of interface bond length on the bond performance of CFRP-concrete interface under sulfate attack. The results show that: 1) After the dry-wet cycle of sulfate, the bond performance of CFRP-concrete interface deteriorated, and the ultimate bearing capacity, ultimate slip and bond stiffness of the CFRP-concrete decreased significantly with the increase of erosion time; 2) As the time of sulfate attack increases, the failure mode of the interface changes, the failure surface is closer to the glue layer, and the triangular shear zone is no longer generated at the loading end; 3) After the dry and wet cycle of sulfuric acid, the effective bond length of the interface increases; 4) Through the fitting analysis of the test data, the formula for calculating the effective bond length considering the influence of the dry and wet cycles of sulfate is given.
Spatial distribution patterns and structure of epigeal nests of soldierless termites in livestock systems in the northwestern Colombian Amazon
Authors: Duran-Bautista Ervin Humprey , Salzar Juan Carlos Suárez , Yalanda-Sepulveda Katherin 
Published: August 2023

Abstract
Soil-feeding termites have adapted to homogeneous and highly disturbed landscapes such as pastures dedicated to cattle ranching, where they build numerous mounds that can affect the useful area of pastures due to the high density of nests. This study evaluated the spatial distribution pattern and structure of the mounds built by two species of soil-feeding termites Patawatermes turricola and Rustitermes boteroi. This work was carried out in pastures of livestock systems in El Doncello municipality in acid soils and low fertility, twenty-five plots of 400 m2 were established where the mounds number present were counted and georeferenced, and the basal perimeter, height, and distance to the nearest neighbor were measured to determine the density of mounds and spatial distribution pattern. Results show a high nest density of 62.5 mounds/ha; however, the presence of these mounds does not compromise the useful area of the pastures due to their low percentage of total area (0.08%). The study showed two distribution patterns (random and regular) that can be related with intraspecific and interspecific competition, environmental conditions and flight distance of the species. P. turricola presented higher mounds and moved the greatest amount of soil; in contrast, R. boteroi presented nests with greater volume and basal perimeter. In general, study showed that presence of numerous mounds in livestock systems does not affect useful area of pastures, since they occupy less than 1% of the area that freely allows livestock activity without any affectation.
Patient-specific computational models of retinal prostheses
Authors: Kish Kathleen E. , Yuan Alex , Weiland James D. 
Published: August 2023

Abstract
Retinal prostheses stimulate inner retinal neurons to create visual perception for blind patients. Implanted arrays have many small electrodes, which act as pixels. Not all electrodes induce perception at the same stimulus amplitude, requiring clinicians to manually establish a visual perception threshold for each one. Phosphenes created by single-electrode stimuli can also vary in shape, size, and brightness. Computational models provide a tool to predict inter-electrode variability and automate device programming. In this study, we created statistical and patient-specific field-cable models to investigate inter-electrode variability across seven epiretinal prosthesis users. Our statistical analysis revealed that retinal thickness beneath the electrode correlated with perceptual threshold, with a significant fixed effect across participants. Electrode-retina distance and electrode impedance also correlated with perceptual threshold for some participants, but these effects varied by individual. We developed a novel method to construct patient-specific field-cable models from optical coherence tomography images. Predictions with these models significantly correlated with perceptual threshold for 80% of participants. Additionally, we demonstrated that patient-specific field-cable models could predict retinal activity and phosphene size. These computational models could be beneficial for determining optimal stimulation settings in silico, circumventing the trial-and-error testing of a large parameter space in clinic.
PPARα suppresses low-intensity-noise-induced body weight gain in mice: the aggravation of fatty liver is covered up
Authors: Liu Aiming , yan zheng , Luo Jia , Dai Manyun , Su Mingli , Jiang Lei , Yang Julin 
Published: August 2023

Abstract

Background As the second risky environmental pollution, noise imposes threats to human health. Exposure to high-intensity noise causes hearing impairment, psychotic disorders, endocrine modifications. However, the relationship among low-intensity noise, obesity and lipid-regulating nuclear factor PPARα is not yet clear.Methods In this study, wild-type (WT) and Pparα-null (KO) mice on a high-fat diet (HFD) were exposed to 75 dB noise for 12 weeks to explore the effect of low-intensity noise on obesity development and the role of PPARα. 3T3-L1 cells were treated with dexamethasone (DEX) to verify the down-stream effect of hypothalamic-pituitary-adrenal (HPA) axis activation on the adipose tissues.Results The average body weight gain (BWG) of WT mice on HFD exposed to noise was inhibited by 34.6%, which was not observed in KO mice. The mass and adipocyte size of adipose tissues accounted for the above difference of BWG tendency. In WT mice on HFD, the adrenocorticotropic hormone level was increased by the noise challenge. The aggravation of fatty liver by noise exposure occurred in both mouse lines, and the transport of hepatic redundant lipid to adipose tissues were similar. The lipid metabolism in adipose tissue driven by HPA axis accorded with the BWG inhibition, validated in 3T3-L1 adipogenic stem cell model.Conclusion Chronic exposure to low-intensity noise aggravated fatty liver in both WT and KO mice. BWG inhibition was observed only in WT mice, which covered up the aggravation of fatty liver by noise exposure. Lipid metabolism in adipose tissues driven by HPA axis activation contributed to the disassociation of BWG and fatty liver development in WT mice.
Analysis of the relationship of axial length, optic disc morphology, and regional variations in retinal vessel density in young adults with healthy eyes
Authors: Chen yanhui , Rong Hua , Liu Yuling , Sun Ziwen , Dang Weiyu , Lu Kunpeng , Mi Baoyue , Li Jing , Wei Ruihua , Gao Huijuan 
Published: August 2023

Abstract
Background
To investigate the relationship between optic disc morphology, axial length, and regional distribution of retinal vessels in healthy eyes of young adults.
Methods
Eighty-hundred and seventy-one healthy eyes were enrolled in this university-based, cross-sectional study. Spectral-domain optical coherence tomography angiography measured the parapapillary retinal vessel density. We evaluated the optic disc tilt and rotation in scanning laser ophthalmoscopy images. Relationships between optic disc rotation, optic disc tilt, parapapillary vessel density, and other ocular parameters were analyzed using regression models.
Results
During axial length, optic disc morphology became more tilted and rotated inferiorly. The superficial vessel density (SVD) and radial peripapillary capillaries density (RPCD) decreased gradually in all regions except for the temporal quadrant. Increased temporal SVD (OR [95% CI] = 1.081 [1.039, 1.124], P < 0.001), reduced nasal SVD, (OR [95% CI] = 0.898 [0.861, 0.937], P < 0.01) and short relative lens position (OR [95% CI] = 0.126 [0.032, 0.495], P = 0.003) were significantly associated with the presence of tilted disc. Inferiorly rotated of the optic disc was associated with decreased superior deep vessel density (DVD) and increased inferior DVD and temporal DVD after adjusting the sex and axial length.
Conclusion
The ovality and inferior rotation of optic discs increased with the axial length elongation, and the tilted and rotated discs were associated with the distribution of SVD and DVD, respectively. We should fully consider the influence of optic disc morphology on parapapillary vessel density in eyes with myopia.
Microbes and Microbial Strategies in Carcinogenic Polycyclic Aromatic Hydrocarbons Remediation: A Systematic Review
Authors: Banerjee Sandipan , Gupta Nitu , Pramanik Krishnendu , Gope Manash , GhoshThakur Richik , Karmakar Animesh , Gogoi Nayanmoni , Hoque Raza Rafiqul , Mandal Narayan Chandra , Balachandran Srinivasan 
Published: August 2023

Abstract

Degradation, detoxification or removal of the omnipresent polycyclic aromatic hydrocarbons (PAHs) from the ecosphere as well as their prevention from entering into food chain has never appeared simple. In this context, cost-effective, eco-friendly and sustainable solutions like microbes-mediated strategies have been adopted worldwide. With this connection, measures have been taken by multifarious modes of microbial remedial strategies, i.e., enzymatic degradation, biofilm and biosurfactant production, application of biochar immobilized microbes, lactic acid bacteria, rhizospheric-phyllospheric-endophytic microorganisms, genetically engineered microorganisms, and microbial fuel cell techniques etc. In this review, a nine-way directional approach which is based on the microbial resources reported over the last couple of decades has been described. Fungi found as the most dominant taxa among the CPAH-degrading microbial community constituting 52.2%, while bacteria, algae and yeasts occupied 37.4%, 9.1% and 1.3%, respectively. In addition to these, category-wise CPAH degrading efficiencies of each microbial taxa, consortium-based applications, CPAH-degradation related molecular tool, and factors affecting CPAH-degradation are the other important aspects of this review in light of their appropriate selection and application in the PAH-contaminated environment for better human-health management in order to achieve a sustainable ecosystem.
Development, characterization, and consumer acceptance evaluation of thermally stable capsule beads containing mixed extracts of green tea and turmeric
Authors: Singh Kanjana , Adhikari Benu , Low Julia , Brennan Margaret Anne , Newman Lisa , Brennan Charles Stephen , Utama-ang Niramon 
Published: August 2023

Abstract
The aim of this study was to investigate the ability of shell (coating) formulations comprised of alginate and glucono delta lactone (GDL) to encapsulate a mixture of green tea and turmeric extracts. Three concentrations (0.5%, 0.75%, and 1%, w/v) of alginate and GDL were used, and their solid ratio was varied using a factorial design. A response surface model was applied to optimize the retention of catechin and curcuminoid contents, encapsulation efficiency, and minimize undesirable flavor and taste. Increasing the concentration of alginate and GDL significantly increased the retention of catechin and curcuminoid contents, encapsulation efficiency, and consumer acceptance (p < 0.05). The encapsulating solution containing 1% of each alginate and GDL performed the best against each criterion. The thermal treatment carried out at boiling point of water for 15 min had a significant impact on retention of catechin and curcuminoid content which in thermally treated beads was 5.15 and 3.85 times higher than unencapsulated, respectively. The consumer acceptance of the encapsulated beads after thermal treatment was higher than unencapsulated formulations as they exhibited lesser pungent flavor and bitterness. Thus, the optimized encapsulating formulations can be used to produce thermally stable microcapsules containing polyphenol-rich mixed plant extracts and used as functional ingredients.
Downregulation of NADPH oxidase 1 and 5 inhibits TPA-induced cell invasion via PKC/ROS-mediated MMP-9 activation in MCF-7 cells
Authors: Song Hyun-Kyung , Kim Jeong-Mi , Noh Eun-Mi , Lee Young-Rae 
Published: August 2023

Abstract
NADPH oxidases (NOXs) are a family of membrane proteins involved in intracellular reactive oxygen species (ROS) production through transferring electrons across biological membranes. NOXs are activated by protein kinase C (PKC); however, the mechanism underlying NOX activation via PKC during breast cancer invasion remains unclear. In this study, we demonstrated that NOX1 and NOX5 play crucial roles in 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced matrix metalloprotease (MMP)-9 expression and invasion of MCF-7 cells. In addition, we show that TPA-induced MMP-9 expression and cell invasion are mediated through PKC, linking the NOX1 and 5/ROS signaling pathways. The expression and activity of NOXs and MMP‑9 were investigated using quantitative real-time polymerase chain reaction (qRT-PCR) and western blotting. The activity of MMP‑9 was determined through zymography. Cell invasion was investigated using the Matrigel invasion assay. ROS levels were determined using a FACSCalibur flow cytometer. NOX inhibitors significantly attenuated TPA-induced MMP-9 expression and invasion in MCF-7 cells. NOX1 and NOX5 specific small interfering RNAs (siRNA) attenuated the TPA-induced MMP-9 expression and cell invasion. TPA-induced ROS levels were suppressed by the knockdown of NOX1 and NOX5. PKC inhibitors suppressed TPA-induced intracellular ROS levels, MMP-9 expression, and NOX activity in MCF-7 cells. Therefore, NOX1 and NOX5 play crucial roles in TPA-induced MMP-9 expression and invasion of MCF-7 breast cancer cells. In addition, TPA-induced MMP-9 expression and cell invasion are mediated through PKC, linking the NOX1 and 5/ROS signaling pathways. These findings provide new insights into the potential mechanisms underlying their anti-invasive effects in breast cancer.
Effect of Small and Large Energy Surpluses on Strength, Muscle, and Skinfold Thickness
Authors: Helms Eric R , Spence Alyssa-Joy , Sousa Colby , Krieger James , Taylor Steve , Oranchuk Dustin J , Dieter Brad P , Watkins Casey M 
Published: August 2023

Abstract
Background
A goal of many who perform resistance training (RT) is to increase muscle mass and strength. An energy surplus is commonly advised to support such gains; however, if too large, it could cause unwanted fat gain without augmenting adaptation. Thus, we randomized 21 trained lifters into maintenance energy (MAIN), 5% (MOD), and 15% (HIGH) energy surplus groups while performing RT 3d/wk for eight weeks to determine if skinfold thicknesses (ST), squat and bench one-repetition maximum (1-RM), or biceps brachii or quadriceps muscle thicknesses (MT) were influenced by group assignment. COVID-19 complications reduced our ability to recruit and retain participants, leaving 17 completers. Thus, in addition to Bayesian ANCOVA group comparisons, we regressed outcomes against body mass (BM) changes to analyze the relationship between BM gain, ST increases, and increase in 1-RM and MT. For all outcomes we reported Bayes Factors (BF10) indicating the odds ratio of the likelihood of one hypothesis relative to another (e.g., a BF10 = 2 indicates the hypothesis is twice as likely as another) and coefficients of determination (R2) for regressions.
Results
ANCOVAs provided no evidence in support of the group model for MT or squat 1-RM. However, there was moderate (BF10 = 9.9) and strong evidence (BF10 = 14.5) that MOD increased bench 1-RM more than HIGH and MAIN, respectively. Further, there was moderate evidence (BF10 = 4.2) MOD increased ST more than MAIN and weak evidence (BF10 = 2.4) HIGH increased ST more than MAIN. The regression provided strong evidence that BM changes predicted changes in ST (BF10 = 14.3, R2 = 0.49) and weak evidence that BM changes predicted changes in biceps MT (BF10 = 1.4, R2 = 0.24), but no evidence any other variable was predicted by BM changes.
Conclusions
While some group-based differences were found, our larger N regression provides the most generalizable evidence. Therefore, we conclude faster rates of BM gain (and by proxy larger surpluses) primarily increase rates of ST gain rather than augmenting 1-RM or MT. However, the biceps, the muscle group which received the greatest stimulus in this study, may have been positively impacted by greater BM gain, albeit slightly. Our findings are limited to the confines of this study, where a group of lifters with mixed training experience performed moderate volumes 3d/wk for eight weeks. Thus, future work is needed to evaluate the relationship between BM gains, increases in ST and RT adaptations in other contexts.
Reproduction of Detailed Forearm Rotation Dynamics Using Intensity- Based Biplane 2D-3D Registration Matching Method; Dynamic Analysis in Distal Radio-ulnar Joint
Authors: Shiode Ryoya , Miyamura Satoshi , Kazui Arisa , Yamamoto Natsuki , Miyake Tasuku , Iwahashi Toru , Tanaka Hiroyuki , Otake Yoshito , Sato Yoshinobu , Murase Tsuyoshi , Abe Shingo , Okada Seiji , Oka Kunihiro 
Published: August 2023

Abstract
This study aimed to reproduce and analyse the in vivo dynamic rotational motion of the forearm and to clarify the forearm motion involvement and anatomical function of the triangular fibrocartilage complex (TFCC). We analysed the in vivo dynamic forearm rotational motion of the radius and the ulna, using a novel image-matching method for intensity-based biplane two-dimensional–three-dimensional (2D–3D) registration. This study included 20 upper limbs of 10 healthy volunteers. The average range of forearm rotation was 69.8 ± 14.8° for pronation and 80.8 ± 13.4° for supination. The radius was most proximal to the maximum pronation, moved distally toward the neutral position, and again proximally toward supination. The average axial translation of the radius during forearm rotation was 0.98 mm. Length changes of four virtual ligaments of TFCC, palmar and dorsal superficial radioulnar ligaments (PSL and DSL) and palmar and dorsal deep radioulnar ligaments (PDL and DDL), were investigated. We found that the PSL and DSL were most tensed in mid-rotation, PDL in pronation, and DDL in supination. The sequential tension of the four ligaments during the forearm rotation motion was found to contribute to the stability of the DRUJ over a wide range of motion. In conclusion, we describe a method for detailed evaluation of in vivo dynamic forearm motion and provide new insight on forearm kinematics and the DRUJ.
Attitudes toward the COVID-19 pandemic and its relationship to mental state among Russian teachers, students and schoolchildren
Authors: Pavlova Anna , Liutsko Liudmila , Malykh Artem , Ismatullina Victoria , Marakshina Julia , Kolyasnikov Pavel , Tabueva Anna , Adamovich Timofey , Zakharov Ilia , Tikhomirova Tatiana , Lobaskova Marina , Symaniuk Elvira , Pecherkina Anna , Khusnutdinova Elza , Sitnikova Maria , Malykh Sergey 
Published: August 2023

Abstract
The COVID-19 pandemic has had a dramatic impact on the mental state of teachers and students, who faced the necessity to teach and study online because of lockdown. The current study aimed to establish the association between attitudes toward the pandemic and the degree of stress, anxiety and depression among teachers and students. A total of 8051 participants constituted the sample. The Hospital Anxiety and Depression Scale (HADS) was used to assess depression and anxiety, and the PSS was used to assess stress. Principal component analysis was implemented to derive latent variables reflecting various attitudes toward the pandemic, and multinomial logistic models were implemented to establish the association between attitudes toward the pandemic and the degree of anxiety, stress and depression. The majority of participants, regardless of their social group, reported low levels of anxiety and depression and medium levels of stress. Overall, worry about COVID-19 itself is negatively associated with anxiety, stress and depression, whereas worry about the side effects of the pandemic has a positive association with those constructs. Additionally, social group moderates the relationship: specifically for teachers, the association between worry about COVID-19 and anxiety and depression tended to be positive. The theoretical explanation and practical implication of the findings are discussed.
Complete Melting of the Moon Inferred from Hafnium Isotope Measurements
Authors: Borg Lars , Gaffney Amy 
Published: August 2023

Abstract
Investigations of lunar rocks demonstrate that the primordial crust and mantle of planetary bodies form through solidification of a magmatic layer, known as a magma ocean. However, the depths of planetary magma oceans are poorly constrained despite the fact that this information would provide critical constrains on the initial conditions under which planetary bodies form and evolve, as well as the geologic significance of measurements made on surficial materials. Here we use Hf and Nd isotopes measured on lunar basaltic rocks to demonstrate that the lunar magma ocean likely encompassed the entire Moon. Complete melting of the Moon implies planetary bodies are unlikely to preserve primitive unprocessed material in their interiors, that chemical equilibrium between planetary cores and mantles is probable, that samples collected on planetary surfaces can record primordial global-scale processes, and that heat associated with accretion is likely responsible for formation of magma oceans. These results have implications for the origin and evolution of all four terrestrial planets as well as all large geologically processed asteroids.