bluuebunny/crossref_metadata_2025_split huggingface dataset:
Self Management dan Kualitas Hidup Penderita Rheumatoid Arthritis
Authors: Apriyeni Emira , Patricia Helena , Rahayuningrum Dwi Christina 
Published: July 2023

<p align="justify"><em>Rheumatoid </em><em>A</em><em>rthritis</em><em> (RA)</em><em> </em><em>menyebabkan keterbatasan aktivitas penderitanya dan akan mempengaruhi kualitas hidup. Keterbatasan aktivitas dan komplikasi penyakit dapat di</em><em> </em><em>minimalkan dengan melaksanakan</em><em> </em><em>self managemen</em><em>t </em><em>untuk</em><em> meningkatkan </em><em>kualitas hidup pasien</em><em>. Pe</em><em>nelitian ini </em><em>bertujuan </em><em>untuk mengetahui </em><em>h</em><em>ubungan self management dengan kualitas hidup penderita rheumatoid arthritis</em><em>. Penelitian dilaksanakan</em><em> </em><em>diwilayah kerja </em><em>P</em><em>uskesmas</em><em> K</em><em>emantan </em><em>K</em><em>abupaten </em><em>K</em><em>erinci </em><em>pada penderita </em><em>Rheumatoid Athritis</em><em>. Sampel penelitian berjumlah 50 orang </em><em>dengan teknik </em><em>Purposive sampling</em><em>. </em><em>Pengumpulan data menggunakan kuesioner </em><em>dan analisa menggunakan u</em><em>ji chi-square. Hasil </em><em>penelitian menunjukkan </em><em>sebagian besar responden mengalami </em><em>k</em><em>ualitas </em><em>h</em><em>idup yang kurang baik</em><em> (</em><em>64,0%</em><em>)</em><em> dan Self Management yang kurang baik</em><em> (68,0%). Hasil analisa lebih lanjut di dapatkan </em><em>p value = 0,000 yang berarti terdapat hubungan antara Self Management dengan Kualitas Hidup penderita Rheumatoid Arthritis</em><em>. Kesimpulan penelitian ini didapatkan ada hubungan antara Self Management dan kualitas hidup pada penderita Rheumatoid Arthritis. Oleh k</em><em>arena itu diharapkan pasien dapat lebih meningkatkan </em><em>self management sehingga kualitas hidupnya semakin baik.</em><em></em></p>
Verification of cuproptosis-related diagnostic model associated with immune infiltration in rheumatoid arthritis
Authors: Jiang Mingyang , Liu Kaicheng , Lu Shenyi , Qiu Yue , Zou Xiaochong , Zhang Ke , Chen Chuanliang , Jike Yiji , Xie Mingjing , Dai Yongheng , Bo Zhandong 
Published: July 2023

BackgroundRheumatoid arthritis (RA) is a chronic autoimmune disease closely related to inflammation. Cuproptosis is a newly discovered unique type of cell death, and it has been found that it may play an essential role in the occurrence and development of RA. Therefore, we intend to explore the potential association between cuproptosis-related genes (CRGs) and RA to provide a new biomarker for the treatment and prognosis of RA.MethodsDownload GSE93777 datasets from the GEO database. Variance analysis was performed on the CRGs that had been reported. Then, the random forest (RF) model and nomogram of differentially expressed CRGs were constructed, and the ROC curve was used to evaluate the accuracy of the diagnostic model. Next, RA patients were subtyped by consensus clustering, and immune infiltration was analyzed in each subgroup to confirm the correlation between CRGs and abundance of immune cells. The expression levels of CRGs were verified by qRT-PCR.ResultsEight differentially expressed CRGs (DLST, DLD, PDHB, PDHA1, ATP7A, CDKN2A, LIAS, DLAT) were screened out by differential analysis to construct an RF model. The ROC curve proved that this model had good diagnostic accuracy. Based on the above eight significant CRGs, a nomogram was built to predict effective and high-precision results. The consensus clustering method identified two CRG patterns. Most of the immune cells were enriched in cluster A, indicating that cluster A may be related to the development of RA. Finally, qRT-PCR verified the expression of eight key genes, further confirming our findings.ConclusionThe diagnosis model of RA based on the above eight CRGs has excellent diagnostic potential. Based on these, patients can be divided into two different molecular subtypes; it is expected to develop a new treatment strategy for RA.
Citizen scientists reveal small but concentrated amounts of fragmented microplastic on Arctic beaches
Authors: Pasolini Franco , Walther Bruno Andreas , Bergmann Melanie 
Published: July 2023

Plastic production and plastic waste have increased to such an extent that it has become globally ubiquitous. Recent research has highlighted that it has also invaded remote Polar Regions including the Arctic, where it is expected to accumulate over time due to transport from distant sources, rising local anthropogenic activities and increasing fragmentation of existing ocean plastics to microplastics (plastic items &lt;5 mm). While a growing body of research has documented microplastics in the atmosphere, cryosphere, sea surface, water column, sediments and biota, contamination levels on Arctic beaches are poorly known. To fill this knowledge gap, we engaged citizen scientists participating in tourist cruises to sample beach sediments during shore visits on Svalbard, Norway. Following drying, sieving, and visual inspection of samples under a binocular microscope, putative plastic particles ≥1 mm were analysed by attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy. Plastic particles ≥1 mm were found in two out of 53 samples from 23 beaches (mean: 196.3 particles kg−1 and 147.4 particles L−1). These pollution levels could be due to our focus on plastic particles ≥1 mm as well as the relatively small sample sizes used during this initial phase of the project. In addition, the coarse substrate on most beaches might retain fewer plastic particles. The two samples with plastic particles ≥1 mm contained six polyester-epoxide particles and 4920 polypropylene fibres. The latter likely originated from a fishing net and points to possibly accelerated plastic fragmentation processes on Arctic beaches. Since fisheries-related debris is an important source of plastic on Svalbard, a build-up of microplastic quantities can be expected to burden Arctic ecosystems in addition to climate change unless efficient upstream action is taken to combat plastic pollution.
Recombination of the right cerebral cortex in patients with left side USN after stroke: fNIRS evidence from resting state
Authors: Shi Shanshan , Qie Shuyan , Wang Hujun , Wang Jie , Liu Tiejun 
Published: July 2023

ObjectiveUnilateral spatial neglect (USN) is an impaired contralesional stimulus detection, response, or action, causing functional disability. After a stroke, the right hemisphere experiences USN more noticeably, severely, and persistently than the left. However, few studies using fNIRS have been reported in cases of USN. This study aimed to confirm weaker RSFC in USN and investigate the potential inherent features in hemodynamic fluctuations that may be associated with USN. Furthermore, these features were combined into a mathematical model for more accurate classification.MethodsA total of 33 stroke patients with right-sided brain damage were chosen, of whom 12 had non-USN after stroke, and 21 had USN after stroke (the USN group). Graph theory was used to evaluate the hemodynamic signals of the brain's right cerebral cortex during rest. Furthermore, a support vector machine model was built to categorize the subjects into two groups based on the chosen network properties.ResultsFirst, mean functional connectivity was lower in the USN group (0.745 ± 0.239) than in the non-USN group (0.843 ± 0.254) (t = −4.300, p &lt; 0.001). Second, compared with the non-USN group, USN patients had a larger clustering coefficient (C) (t = 3.145, p &lt; 0.001), local efficiency (LE) (t = 3.189, p &lt; 0.001), and smaller global efficiency (GE) (t = 3.047, p &lt; 0.001). Notably, there were differences in characteristic path length (L) and small worldness (σ) values between the two groups at certain thresholds, mainly as higher L (t = 3.074, p &lt; 0.001) and lower small worldness (σ) values (t = 2.998, p &lt; 0.001) in USN patients compared with non-USN patients. Finally, the classification accuracy of the SVM model based on AUC aC (t = −2.259, p = 0.031) and AUC aLE (t = −2.063, p = 0.048) was 85%, the sensitivity was 75%, and the specificity was 89%.ConclusionThe functional network architecture of the right cerebral cortex exhibits significant topological alterations in individuals with USN following stroke, and the sensitivity index based on the small-world property AUC may be utilized to identify these patients accurately.
The development of an immersive mixed-reality application to improve the ecological validity of eating and sensory behavior research
Authors: Long John W. , Masters Bart , Sajjadi Pejman , Simons Christopher , Masterson Travis D. 
Published: July 2023

IntroductionThe modern eating environment has been implicated as a driving force of the obesity epidemic. Mixed reality applications may improve traditional methodological assessments of eating behavior by improving the ecological validity of the laboratory setting.MethodsResearch experts evaluated the utility and ecological validity of a mixed reality application that allowed immersion within virtual environments through utilizing the passthrough cameras of the head mounted display to view and interact with real foods. An initial evaluation was conducted that involved three virtual environments: a traditional laboratory booth, a non-textured restaurant, and a full-textured restaurant. The feedback from the initial evaluation was used to create a new virtual restaurant environment and a subsequent evaluation was conducted.ResultsNearly all research experts suggested adding social cues such as people and background noise to create a more authentic and ecologically valid experience. The experts scored the new virtual restaurant environment to be more acceptable than eating or conducting research in a sensory booth but scored lower when compared to conducting research in a real-world restaurant setting.DiscussionThe results of this evaluation suggest that mixed reality applications may be a new methodology to assess environmental influences of eating behavior and may be a promising direction for eating behavior and sensory science research.
Responses of phenology, yield attributes, and yield of wheat varieties under different sowing times in Indo-Gangetic Plains
Authors: Sattar Abdus , Nanda Gangadhar , Singh Gulab , Jha Ratnesh Kumar , Bal Santanu Kumar 
Published: July 2023

A field experiment with wheat was conducted at Pusa (25.98°N, 85.67°E, 52 m amsl), Bihar (middle Gangetic plains of India), to assess the responses of phenology, yield attributes, and yield to growing season temperature and heat stress. For this purpose, wheat was planted on five dates (viz., 15 November, 25 November, 5 December, 15 December, and 25 December) for three consecutive years (viz., 2014–2015, 2015–2016, and 2016–2017) with three prominent cultivars of the region (viz., RAU-3711, HD-2824, and HD-2733). Five dates of sowing represent different wheat-growing micro-environments as imposed by varying sowing dates encompassing the entire sowing window. The study observed the significant effect of sowing dates on phenophase duration. In general, with progress in the date of sowing, tiller initiation was delayed, while the reverse trend was observed for later growth phases. Sowing environments significantly influenced the number of effective tillers m−2. Average numbers of effective tillers (ET) m−2 for the wheat sown during 15–25 November were almost 11.6% higher than those of the 25 December sown crop. Grain filling duration (GFD) showed a declining trend with the advancement of sowing dates due to increased thermal load on the crop during the reproductive period. 15 November planted crop exhibited the highest GFD (47 days), which was shortened significantly beyond 25 November, signifying agrometeorological non-suitability of wheat sowing beyond this window. Wheat sown on 25 November recorded the highest grain yield (3.21 Mg ha−1), 48.61% higher than the 25 December sown crop due to the congenial thermal regime. In this context, we have identified optimal and sub-optimal conditions to escape heat stress for higher wheat productivity. Moreover, the sum of deviation of temperature from optimum thresholds, computed for sensitive growth phases (50% flowering to physiological maturity), helped us to identify heat stress and its impact on wheat. Genotype-by-environment (GGE) biplot analysis revealed that RAU-3711 was found to be the most stable cultivar. A decrease in the yield of wheat by 4.9% to 12.0%, sown during November, and 33.8% to 42.4%, sown during December, is predicted in 2050-51 and 2080-81, respectively, under RCP 4.5.
Comparing reappraisal and acceptance strategies to understand the neural architecture of emotion regulation: a meta-analytic approach
Authors: Monachesi Bianca , Grecucci Alessandro , Ahmadi Ghomroudi Parisa , Messina Irene 
Published: July 2023

IntroductionIn the emotion regulation literature, the amount of neuroimaging studies on cognitive reappraisal led the impression that the same top-down, control-related neural mechanisms characterize all emotion regulation strategies. However, top-down processes may coexist with more bottom-up and emotion-focused processes that partially bypass the recruitment of executive functions. A case in point is acceptance-based strategies.MethodTo better understand neural commonalities and differences behind different emotion regulation processes, in the present study, we applied the Activation Likelihood Estimation (ALE) method to perform a meta-analysis on fMRI studies investigating task-related activity of reappraisal and acceptance. Both increased and decreased brain activity was taken into account in the contrast and conjunction analysis between the two strategies.ResultsResults showed increased activity in left-inferior frontal gyrus and insula for both strategies, and decreased activity in the basal ganglia for reappraisal, and decreased activity in limbic regions for acceptance.DiscussionThese findings are discussed in the context of a model of common and specific neural mechanisms of emotion regulation that support and expand the previous dual-routes models. We suggest that emotion regulation may rely on a core inhibitory circuit, and on strategy-specific top-down and bottom-up processes distinct for different strategies.
Food literacy competencies in youth – a mini-review
Authors: Groufh-Jacobsen Synne , Medin Anine Christine 
Published: July 2023

IntroductionYoung people’s transition into adulthood is an opportunity in the life course to establish adequate eating behaviors, hence exploring food literacy competencies in this period of life is especially important. Food literacy has recently gained increased attention in adults, adolescents, and younger children, but less is published about youth. This paper aims to summarize what tools have been used to measure food literacy and the sub-competence nutrition literacy in youth aged 16–24 years in the previous 5 years.MethodsA mini-literature review was conducted in MEDLINE and EMBASE via Ovid, in September 2022. Study eligible criteria; had to be an original article, using a tool to quantitatively assess food literacy and/or nutrition literacy, including participants between 16–24 years, full text available in English, published between 2017–2022.ResultsA total of 958 articles were identified, of which 385 duplicates were removed. Thus, 573 articles were screened by title/abstract. Finally, nine articles were eligible for data extraction of which four proposed a tool to measure food literacy and five proposed a tool to measure nutrition literacy.Discussion and conclusionAlthough four studies claimed to measure food literacy, none of these used tools comprehensive enough to measure all aspects of food literacy, and only one was validated in young people. This study shows that only few tools exist for the measurement of food literacy in youth, and those available are scant. Further work is needed to develop a food literacy tool for youth.
Improving Students' Basic Arabic Writing Skills (Imla Manzur) Through The Card Sort Method
Authors: Yusuf Salma Sabila , Abdurrahman Maman , Khalid Shofa Musthofa 
Published: July 2023

This with the card sort method. Of the 56 samples taken randomly and classified into two classes research is quasi-experimental research conducted on class VIII students of SMP Mathlaul Anwar Margahayu, whose sample consists of two classes: experimental and control. This study aimed to determine the results of improving students' basic Arabic writing skills after learning imla manzur in collaboration with different treatments, it was found that there was a difference between the results of the writing ability of the experimental class and the results of the control class' writing ability which was indicated by the results of the hypothesis testing of 0.000. The value of 0.000 <0.05 resulted in Ho being rejected and Ha is accepted, or it can be concluded that there was a significant influence on the learning outcomes of the imla manzur class applying the card sort method.
Keywords : arabic writing skills, card sort method, imla manzur
Le voyage de Rida en Inde et au Koweït
Authors: Ezzahoui Ikrame 
Published: July 2023

En mai 1912, se crée au Koweït, sous l’influence combinée des courants réformistes d’Égypte et de l’océan Indien, la première école qualifiée de « moderne » du pays, la Moubarakiya. Au même moment se tient à Lucknow le dixième congrès de l’Association des Oulémas indiens qui rassemble les intellectuels réformistes influencés par l'héritage du célèbre Sayyid Ahmad Khan mort en 1898. A ces deux événements, la présence de la figure syrienne de la Nahda islamique Rashid Rida, constitue un fait historique assez peu connu malgré son intérêt, à une période où les idées du réformisme connaissent un gain de circulation inédit dans les villes portuaires du golfe Persique. Le récit qu’il en délivre montre comment le thème de l’éducation est à l’époque investi d’un sens politique par les élites musulmanes de l’océan Indien, région connectée par ses synapses portuaires où se tissent, s’entrecroisent et se soutiennent des réseaux mercantiles et intellectuels.
INCIDENCIA DEL RADÓN-222 EN LA RADIACTIVIDAD DE FONDO EN ALGUNAS VIVIENDAS DE EL VALLE DE ANTÓN, PANAMÁ
Authors: Santana M. Lisseth A. , Marín Luis A. , Rodríguez Juan , Arroyo Alejandro , Dreyfus Carlos , Fernández Bernardo , Pérez Castro Omayra J. 
Published: July 2023

Este trabajo se enmarcó en el programa que desarrolla la Estación RN50 para caracterizar el origen de la radiactividad de fondo, a nivel de la República de Panamá. El Radón-222 es un gas que proviene de la cadena natural de desintegración del 238U que se encuentra, mayormente, en rocas volcánicas profundas. De acuerdo con las características del suelo volcánico, el radón puede emanar en mayor o menor cantidad del suelo, en esas zonas. Las mediciones se realizaron durante 2021 y 2022, en El Valle de Antón, que es la zona volcánica más accesible de las cuatro identificadas en Panamá. Para medir las concentraciones de Rn-222, se utilizó el equipo RAD7. Por la incidencia del agua en la propagación del Rn-222 en suelos, se midió en los periodos lluvioso, intermedio o de transición y seco. En la estación seca, la mejor captación en los suelos exteriores de las viviendas se obtuvo durante el mes de marzo . Durante los meses de octubre y mayo, se registraron las dosis más altas de radiactividad equivalente en el interior de las viviendas En conclusión, la contribución a la radiactividad de esta región volcánica es pequeña, por lo que se recomienda mantener una buena ventilación en las viviendas.
Laser‐Assisted Direct Ink Writing for High‐Fidelity Fabrication of Elastomeric Complex Structures
Authors: Shang Erwei , Li Guodong , Zhao Zilong , Zhang Nana , Fan Daming , Liu Yu 
Published: July 2023

AbstractPolydimethylsiloxane (PDMS) is extensively applied in the 3D printing field due to its excellent biocompatibility, flexibility, and gas permeability. However, as a thermal curing material, its low strength before curing inevitably causes structural deformation during the printing process and deteriorates the shape accuracy. In this paper, an innovative method, the infrared laser‐assisted direct ink writing (DIW) process, is developed to realize the in situ preheating and curing of silicone materials to improve the strength of PDMS filaments during processing. Therefore, the large‐span spatial structure with high‐fidelity morphology can be produced. First, the feasibility is validated that temperature ascension of the voxels arising from the irradiation energy of the infrared laser can accelerate the cross‐linking reaction and realize the precuring of PDMS; then, the relationship between the parameters of laser irradiation and the processing performance of 3D printing is systematically investigated to find the optimization. Finally, experiments are conducted, including the single silicone filament, silicone foams, and complex 3D features. Their excellent structural preservation proves the proposed method is practical to fabricate the high‐fidelity fabrication of complex structures such as large spans and thin wall features, which will help to broaden the 3D printing capabilities of silicone in the development of flexible electronics and soft robots.
One‐Pot Access to Tetrasubstituted 2‐Aminothiophenes via Regio‐ and Chemoselective Domino Reactions of Dithioesters with Fumaronitrile at Room Temperature
Authors: Yadav Anup Kumar , Kumar Vipin , Pali Pragya , Ray Subhasish , Verma Abhineet , Singh Maya Shankar 
Published: July 2023

AbstractHerein, we report a one‐pot viable protocol to synthesize tetrasubstituted 2‐aminothiophenes engaging readily accessible α‐enolic dithioesters and abundant fumaronitrile under transition metal‐free conditions at room temperature in open air. The reaction proceeds via successive Michael‐type addition/intramolecular cyclization/isomerization cascades. The added features are benign conditions, exclusive regio‐ and chemoselectivity, excellent atom‐/step‐economy, easy purification, and tolerance of wide range of functional groups of a diverse electronic and steric nature. This protocol not only provided a robust and modular approach to various 2‐aminothiophenes in moderate to excellent yields, but also demonstrated the potential of dithioesters and fumaronitrile in the challenging intermolecular cross‐coupling reactions widening the arsenal of synthetic methods.
A Cationic Metal Glue Strategy for Expanding Paramagnetic Hetero‐Multinuclear Metal‐Oxo Clusters within Polyoxometalate Ligands
Authors: Minato Takuo , Sadakane Masahiro 
Published: July 2023

AbstractPrecise structural design of large hetero‐multinuclear metal‐oxo clusters is crucial for controlling their large spin ground states and multielectron redox properties for application as a single‐molecule magnet (SMM), molecular magnetic refrigeration, and efficient redox catalyst. However, it is difficult to synthesize large hetero‐multinuclear metal oxo clusters as designed because the final structures are unpredictable when employing conventional one‐step condensation reaction of metal cations and ligands. Herein, we report a “cationic metal glue strategy” for increasing the size and nuclearity of hetero‐multinuclear metal‐oxo clusters by using lacunary‐type anionic molecular metal oxides (polyoxometalates, POMs) as rigid multidentate ligands. The employed method enabled the synthesis of {(FeMn4)Mn2Ln2(FeMn4)} oxo clusters (Ln=Gd, Tb, Dy, and Lu), which are the largest among previously reported paramagnetic hetero‐multinuclear metal‐oxo clusters in POMs and showed unique SMM properties. These clusters were synthesized by conjugating {FeMn4} oxo clusters with Mn and Ln cations as glues in a predictable way, indicating that the “cationic metal glue strategy” would be a powerful tool to construct desired large hetero‐multinuclear metal clusters precisely and effectively.