bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efficacy of immersive extended reality (XR) interventions on different symptom domains of schizophrenia spectrum disorders. A systematic review
Authors: Holopainen Roope , Tiihonen Jari , Lähteenvuo Markku 
Published: August 2023

IntroductionExtended reality (XR) is an umbrella term for virtual reality (VR) and augmented reality (AR), both novel vectors for therapeutic intervention modalities. In VR, head-mounted devices (HMD) allow interaction with three-dimensional virtual environments and simulated avatars, while AR overlaps virtual, simulated objects to observe physical reality. Treatment through immersive VR has been studied in psychiatry, including patients suffering from schizophrenia spectrum disorders, while there has not been much attention to AR technologies in psychiatry. Our systematic review aimed to examine the currently available literature regarding the treatment efficacy of immersive VR or AR technologies on different symptom domains of schizophrenia spectrum disorders, screen for potential adverse effects, and gather data on the technological and human resource requirements of such interventions to help guide future research.MethodsWe conducted a systematic literature review with database searches carried out between 9/2021 and 8/2022 through PubMed, Scopus, EBSCOhost Academic Search Premier, and Web of Science.ResultsWe identified 2,157 records, 214 were assessed further for eligibility and 12 met inclusion criteria. All included articles studied immersive VR and none used AR technology. Included studies were heterogenous in nature, including AVATAR therapy (3) and CBT-based (5) VR interventions, as well as cognitive (2), social (1), and relaxation (1) training through VR. The comparison groups were either passive controls (waitlist and treatment as usual), therapeutic interventions (CBT and Integrated psychological treatment), passive VR environments, or traditional, comparable, non-virtual treatment modalities (social roleplay and progressive muscle relaxation training). Pooled together, the included studies on VR show positive treatment effects in all major symptom domains of schizophrenia spectrum disorders with hardly any adverse effects related to the intervention modalities.ConclusionsIn this review, we have showcased how different symptom domains can be targeted through VR interventions, highlighting VR as a potential new vector for a diverse range of psychosocial therapeutic modalities that allow for completely new possibilities in the treatment of schizophrenia spectrum disorders. VR technology still requires more research and validation. Our review also shows that there are currently no studies examining AR technology in the treatment of schizophrenia spectrum disorders, indicating a distinctive research gap.
Analysis of the disease burden of cardiomyopathy in children aged 0–14 years in China from 1990 to 2019
Authors: Kong Qingyu , Li Meng , Wang Minmin , Zhao Haizhao , Yang Xiaorong , Zhao Cuifen 
Published: August 2023

ObjectivesTo assess the disease burden and changing trend of cardiomyopathy in children aged 0–14 years in China from 1990 to 2019.MethodsThis study was based on the Global Burden of Disease Study 2019; the age-specific prevalence rate, mortality rate and disability-adjusted life year (DALY) rate were used for analysis. Estimated annual percentage change (EAPC) in burden rate and its 95% confidence interval were calculated. The data of China were compared with the global average level.ResultsIn 2019, the numbers of prevalence, deaths, and DALYs of cardiomyopathy in children aged 0–14 years in China were 4,493 [95% uncertainty interval (UI): 2687 ~ 6,838], 434 (95%UI: 337 ~ 565) and 37,522 (95%UI: 29,321 ~ 48,891), with declining amplitudes of 16.32, 70.56, and 70.74%, compared with 1990, respectively. In 2019, the prevalence rate of cardiomyopathy in Chinese children aged 0–14 years was 2.00/100,000 (95%UI: 1.2/100,000 ~ 3.04/100,000), higher than 1990 [1.66/100,000 (95%UI:1.00/100,000 ~ 2.53/100,000)]; mortality rate was 0.19/100,000 (95%UI: 0.15/100,000 ~ 0.25/100,000), significantly lower than 1990 [0.46/100,000 (95%UI: 0.25/100,000 ~ 0.95/100,000)]; DALY rate was 16.69/100,000 (95%UI: 13.04/100,000 ~ 21.75/100,000), also significantly lower than 1990 [39.71/100,000 (95%UI: 22.06/100,000 ~ 82.8/100,000)]. All burden rates of cardiomyopathy in Chinese children aged 0–14 years old were all lower than the global averages of 2019; the burden rates of male children were higher than female children. In all calendar years from 1990 to 2019, the mortality and DALY rates of children younger than 1-year-old were significantly higher than in the other age groups of 0–14 years old. From 1990 to 2019, the prevalence rate of cardiomyopathy aged 0–14 years old gradually increased, with EAPC of 0.82 (95%CI: 0.71–0.93); mortality rate and DALY rate decreased [EAPC = −2.32 (95%CI: −2.59 to −2.05)].ConclusionFrom 1990 to 2019, the disease burden of cardiomyopathy in children of China aged 0–14 years was heterogeneous; the burden of male children was higher than females; and the burden of cardiomyopathy in children younger than 1 year old needs more attention.
Positive adult experiences as turning points for better adult mental health after childhood adversity
Authors: Crandall AliceAnn , Magnusson Brianna M. , Barlow Melissa J. , Randall Hannah , Policky Abigail L. , Hanson Carl L. 
Published: August 2023

BackgroundThe purpose of this study was to examine whether positive adult experiences (PAEs) were associated with lower odds for anxiety and depression even in the presence of high adverse childhood experiences (ACEs) or low positive childhood experiences (PCEs).MethodsThe sample was comprised of 435 adults (48% female), ages 18–56 years and who were living in the United States. Participants completed a survey about their childhood experiences, PAEs, and mental health. A series of multiple logistic regression models were estimated in Stata 17 to examine the aims.ResultsPositive childhood experiences were associated with higher PAE scores, but ACEs did not significantly correlate with PAEs. Positive adult experiences were associated with lower odds of moderate-to-severe anxiety and depression, especially among those who had experienced high ACEs or low PCEs. Younger adults were more likely to experience a positive benefit from PAEs compared to adults 35 years and older.ConclusionEven when ACEs were high or PCEs were low, adults with high PAEs had lower odds for moderate-to-severe anxiety and/depression. Positive adult experiences may be an opportunity to turn the tide for individuals who experienced childhood adversity and/or low levels of support or connection.
Use of viability PCR for detection of live Chlamydia trachomatis in clinical specimens
Authors: Vojtech Lucia , Paktinat Shahrokh , Luu Tiffany , Teichmann Stella , Soge Olusegun O. , Suchland Robert , Barbee Lindley A. , Khosropour Christine M. 
Published: August 2023

BackgroundThe current testing approach to diagnose Chlamydia trachomatis (CT) infection relies on nucleic acid amplification tests (NAATs). These tests are highly sensitive, but do not distinguish between active infection and residual bacterial nucleic acid which may remain after resolution of infection, or via cross-contamination. Better methods to assess the viability of CT detected in clinical samples would be useful in determining the relevance of CT detection in a variety of clinical settings. The goal of this study was to test viability PCR (vPCR) as a method to distinguish viable bacteria from non-viable CT.MethodsThe vPCR relies on a propidium monoazide dye (PMAxx), which intercalates into accessible DNA from dead organisms and prevents their detection in a PCR assay for the CT ompA gene. We used digital PCR to quantify absolute genome copy numbers from samples. We validated the vPCR approach using laboratory stocks of CT with known viability. Then, we tested total DNA, viable CT DNA, and culture results from 18 clinical vaginal specimens and 25 rectal clinical specimens, all of which had tested positive by NAAT.ResultsIn laboratory stocks of CT, vPCR using defined ratios of heat-killed to live bacteria tracked closely with expected results. In vaginal clinical specimens, vPCR and total DNA results were correlated, though total DNA genomes outnumbered viable genomes by 2.2–52.6-fold more copies. As expected, vPCR detected more total genomes than culture results. Both vPCR and total DNA correlated with culture results (Spearman correlation R = 0.8425 for total DNA and 0.8056 for vPCR). Ten rectal NAAT positive specimens were negative by total DNA PCR, vPCR, and were negative or inconclusive by culture. Of the 6 rectal specimens that were culture positive, all were total DNA and vPCR positive. vPCR additionally detected viable bacterial DNA in 8 specimens which were NAAT + and culture negative, though levels were very low (mean 1,357 copies/ml)ConclusionsvPCR is a fast and easy method to assess viability in clinical specimens and is more correlated with culture results than total DNA PCR. Inconsistent ratios between total DNA and vPCR results suggest that the amount of dead bacteria varies considerably in clinical specimens. Results from rectal specimens suggest that many NAAT positive specimens do not in fact represent live replicating bacteria, and likely result in significant overuse of unnecessary antibiotics.
Comparing the influence of mixed reality, a 3D viewer, and MRI on the spatial understanding of brain tumours
Authors: Fick T. , Meulstee J. W. , Köllen M. H. , Van Doormaal J. A. M. , Van Doormaal T. P. C. , Hoving E. W. 
Published: August 2023

Background: Multiple 3D visualization techniques are available that obviates the need for the surgeon to mentally transform the 2D planes from MRI to the 3D anatomy of the patient. We assessed the spatial understanding of a brain tumour when visualized with MRI, 3D models on a monitor or 3D models in mixed reality.Methods: Medical students, neurosurgical residents and neurosurgeons were divided into three groups based on the imaging modality used for preparation: MRI, 3D viewer and mixed reality. After preparation, the participants needed to position, scale, and rotate a virtual tumour inside a virtual head of the patient in the same orientation as the original tumour would be. Primary outcome was the amount of overlap between the placed tumour and the original tumour to evaluate accuracy. Secondary outcomes were the position, volume and rotation deviation compared to the original tumour.Results: A total of 12 medical students, 12 neurosurgical residents, and 12 neurosurgeons were included. For medical students, the mean amount of overlap for the MRI, 3D viewer and mixed reality group was 0.26 (0.22), 0.38 (0.20) and 0.48 (0.20) respectively. For residents 0.45 (0.23), 0.45 (0.19) and 0.68 (0.11) and for neurosurgeons 0.39 (0.20), 0.50 (0.27) and 0.67 (0.14). The amount of overlap for mixed reality was significantly higher on all expertise levels compared to MRI and on resident and neurosurgeon level also compared to the 3D viewer. Furthermore, mixed reality showed the lowest deviations in position, volume and rotation on all expertise levels.Conclusion: Mixed reality enhances the spatial understanding of brain tumours compared to MRI and 3D models on a monitor. The preoperative use of mixed reality may therefore support the surgeon to improve spatial 3D related surgical tasks such as patient positioning and planning surgical trajectories.
The Occurrence and Characteristics of Methicillin-Resistant Staphylococcal Isolates from Foods and Containers
Authors: Kansaen Rada , Boueroy Parichart , Hatrongjit Rujirat , Kamjumphol Watcharaporn , Kerdsin Anusak , Chopjitt Peechanika 
Published: August 2023

Antimicrobial resistance (AMR) has emerged as an urgent global public health issue that requires immediate attention. Methicillin-resistant staphylococci (MRS) is a major problem, as it may cause serious human and animal infections, eventually resulting in death. This study determined the proportional distribution, genetic characteristics, and antimicrobial susceptibility of mecA- or mecC-carrying staphylococci isolated from food chain products. A total of 230 samples were taken from meat, food, fermented food, and food containers. Overall, 13.9% (32/230) of the samples were identified to have Staphylococcus aureus isolates; of those, 3.9% (9/230) were MRS, with eight mecA-positive and one mecC-positive samples, and 1.3% (3/230) methicillin-resistant Staphylococcus aureus (MRSA). MRSA strains belonging to three sequence types (ST9, ST22, and a newly identified ST), three different spa types (T005, t526, and a newly identified type), and three different SCCmec types (IV, V, and an unidentified SCCmec) were detected. Additionally, eight mecA-positive staphylococcal isolates were identified as S. haemolyticus, S. sciuri, S. simulans, and S. warneri, while the mecC-harboring isolate was S. xylosus. The enterotoxin gene, SEm, was detected at 1.56% in S. aureus, whereas SEq was detected at 0.31%, and SEi was also found in MRSA. Our study emphasizes the importance of enhanced hygiene standards in reducing the risk of occupational and foodborne MRSA infections associated with the handling or consumption of meat, food, and preserved food products.
PENGARUH MODEL PROBLEM-BASED LEARNING TERHADAP KETERAMPILAN BERPIKIR KRITIS SISWA KELAS XI MIA SMA NEGERI 10 GOWA
Authors: Sinusi Nur Suhaiba 
Published: August 2023

Abstrak : Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran problem-based learningterhadap peningkatan keterampilan berpikir kritis siswa pada kelas XI MIA SMA Negeri 10 Gowa. Sampel dalam penelitian ini adalah siswa kelas XI MIA 2 sebagai kelas eksperimen dan kelas XI MIA 3 sebagai kelas kontrol yang diperoleh dengan menggunakan teknik simple random sampling. Penelitian ini menggunakan rancangan penelitian eksperimen semu pretest-posttest nonequivalent control group design. Keterampilan berpikir kritis diukur dengan menggunakan tes essay pada materi sistem sirkulasi. Data yang diperoleh dianalisis secara statistik deskriptif dan statistik inferensial dengan anakova. Hasil penelitian menunjukkan bahwa (1) rata-rata nilai keterampilan berpikir kritis siswa yang dibelajarkan dengan model problem-based learningadalah 73 yang masuk dalam kategori tinggi; (2) terdapat pengaruh pengaruh model pembelajaran Problem-based learning terhadap keterampilan berpikir kritis siswa dengan nilai signifikansi 0.00.
Pengaruh Model Pembelajaran Berbasis Masalah Terhadap Hasil Belajar Biologi dan Keterampilan Berpikir Kritis Peserta Didik
Authors: Patmawati Patmawati , Hala Yusminah , Arsyad Muhammad 
Published: August 2023

Influence Of Problem Based Learning Model To Biology Learning Outcomes And Critical Thinking Skill Of Students. This research is a quasi experimental with pretest posttest control group design which aims to determine critical thinking skills and learning outcomes. The research sample was randomly selected and the XII IPA 1 was selected as the control and the XII IPA 3 as experimental class. The technique of collecting data was through giving test description to measure critical thinking skills and multiple choice test to measure biology learning outcomes. The data analysis technique used are descriptive and inferential statistics analysis with the independent sample t-test. The result of descriptive analysis show that students who are taught with the model problem based learning have critical thinking skills and learning outcomes in the middle category. While the results of inferential analysis show that there are differences in critical thinking skills and learning outcomes of students who are using the problem based learning model and conventional learning, that show average value of problem-based learning model are higher. The results show the problem based learning model has a positive effect on critical thinking skills and biology learning outcomes in mutation topic at SMAN 10 Luwu Utara.
Pengaruh Model Pembelajaran Guided Discovery terhadap Peningkatan Hasil Belajar dan Efikasi Diri Peserta Didik
Authors: Wahidah Nur , Hala Yusminah , Arsyad Muhammad 
Published: August 2023

This study is a quasi-experimental research that aims to examine whether there is an influence of Guided Discovery learning model on learning outcomes and students’ self-efficacy with pretest-posttest control group design. Data on learning outcomes were obtained through pre-test and post-test by giving a written test in the form of multiple choice questions with 30 questions, while self-efficacy data was also obtained through pre-test and post-test from filling out a self-efficacy questionnaire with 30 statements. The data analysis technique employed descriptive statistical analysis, N-Gain, and inferential with t test (independent sample test). The results of descriptive analysis show that (1) the learning outcomes of experimental class students are in moderate category. (2) for self-efficacy of experimental class students in moderate category. (3) the learning outcomes in the control class is in low category. (4) the students’ self-efficacy in the control class is in low category (5) the results of inferential statistical analysis show that there is a significant influence of implementing Guided Discovery learning model on the improvement of learning outcomes and self-efficacy of grade VIII students at SMPN Gollek No. 34 Selayar Islands.
Detection of Book and Borrower Communities Based on Book Borrowing Records in the Library Using Complex Network Analysis
Authors: Setiadi Tedy , Ratih Rina , Arkiyah Nanik , Prestisia Gretha 
Published: August 2023

To improve user services, libraries need to have deep insight into users and the books they manage. This study aims toidentify the community of users and borrowed books based on book borrowing records using complex network analysis. It starts with collecting book-borrowing data, then converting it into a bipartite book-borrowing network using python programming and visualizing it with Gephi. Network analysis is performed to investigate network properties, and to use the BIMLPA method to find communities. The results of the investigation show that the structure of the book borrowing network is divided into two separate components. One main component of the network represents the optimal process of borrowing books, and the rest consists of many small components representing suboptimal borrowing. Community detection on the main component found 217 borrowing communities and 141 book communities. Most of the communities are small, where the book community is 2-4 members, while the borrowing community is in the form of individual borrowers. This research also produces the top 5 book communities, and borrower communities, the most popular books, and the most active borrowers. The characteristics of the users and the books found can be used as a library reference for a more effective and efficient book development policy strategy, as well as book recommendations for more targeted users.
TAMAN KOTA DAN KESEHATAN MENTAL: ANALISIS FREKUENSI MENGUNJUNGI TAMAN LAPANGAN BANTENG JAKARTA
Authors: Yoga Aji Nugraha  , Tsurrayya Syarif Zain  , Melisa Kurnia Asfitri  , Welan Mauli Angguna  
Published: August 2023

Several phenomena that occur at this time such as those that occur in Bandung and Surabaya and even Jakarta about revitalizing city parks because of its relation to improving mental health of urban communities. A number of studies have examined this relationship, even with several factors and mediation in the utilization of city parks. In this study the frequency of visiting city parks became the factor studied in relation to improving mental health in urban communities. The study design was non-experimental with correlation analysis. The study was conducted on 62 participants who used the city park with incidental sampling techniques. The results of the study show that the more frequent the city park visits, the more the mental health of urban communities will be increased with a significance of .033 with p = .000 and p <.05. Keywords: Mental health, urban communities, frequency of visits, city parks
Beberapa fenomena saat ini seperti yang terjadi di Bandung dan Surabaya bahkan Jakarta yaitu tentang revitalisasi taman kota karena dikaitkan dengan peningkatan kesehatan mental masyarakat perkotaan. Sejumlah penelitian telah mengkaji hubungan tersebut, bahkan dengan beberapa faktor dan mediasi dalam pemanfaatan taman kota. Dalam penelitian ini frekuensi mengunjungi taman kota menjadi faktor yang diteliti dalam kaitannya dengan peningkatan kesehatan mental masyarakat perkotaan. Desain penelitian adalah non eksperimen dengan analisis korelasi. Penelitian dilakukan terhadap 62 partisipan yang menggunakan taman kota dengan teknik sampling insidental. Hasil penelitian menunjukkan bahwa semakin sering berkunjung ke taman kota maka kesehatan mental masyarakat perkotaan akan semakin meningkat dengan signifikansi 0,033 dengan p = 0,000 dan p < 0,05. Kata Kunci: Kesehatan mental, masyarakat perkotaan, frekuensi kunjungan, taman kota
Optimalisasi Peran Kader Posyandu Dalam Pelayanan Stunting
Authors: Nurhayati Siti 
Published: August 2023

Stunting merupakan masalah kesehatan dimana anak mengalami kekurangan gizi kronis akibat tidak adekuatnya asupan gizi dalam periode yang lama. . Indonesia menempati urutan ke-10 di Asia Tenggara dengan prevalensi stunting pada anak balita sekitar 31,8%. Berdasarkan hasil Survei Status Gizi Indonesia angka kejadian balita stunting di Indonesia telah menembus angka 21,6% pada tahun 2022. Literature Review, dipilih menjadi metode dalam studi ini dengan menganalisis berbagai sumber kepustakaan dalam database Google Scholar yang selaras dengan kata kunci yang telah ditentukan: peran kader, dan stunting. Tujuannya untuk mengetahui bagaimana mengoptimalkan peran kader posyandu dalam menangani stunting di Indonesia. Hasilnya didapatkan sembilan referensi yang relevan dengan kriteria inklusi dan eksklusi untuk kemudian dianalisis. Berdasarkan analisis artikel dapat disimpulkan bahwa peran kader posyandu dapat dioptimalkan dengan memberikan pelatihan dan pembekalan untuk meningkatkan pengetahuan, dan ketrampilan khususnya dalam menangani keluarga berisiko dengan anak stunting.
Profile of Cholelithiasis Underwent Laparoscopic Cholecystectomy Patients at The Aloei Saboe Hospital
Authors: Abdul Romy , Ariyanti Safera , Kasim Vivien Novarina A. , Yusuf Muh Nur Syukriani , Ibrahim Nurliana 
Published: August 2023

Introduction: Cholelithiasis is one of the critical health problems. Modern lifestyles can allow gallstone disease in Indonesia to become a health problem that needs attention. The research objective is to know the profile of patients with cholelithiasis who performed laparoscopic cholecystectomy in Aloei Saboe Hospital.Method: The research design is a retrospective descriptive study. The population of this study was cholelithiasis patients who underwent laparoscopic cholecystectomy and were treated from January 2020 - December 2021, totaling 234 people. The number of samples is 86 people. We were using a purposive sampling data analysis technique, namely univariate analysis.Results: Regarding the distribution of patients based on sex, the most results were obtained from females (70 people, 81.4%), the largest age group is 46-55 years old (23 people, 26.7%), and the majority of patients did not have a history of diabetes mellitus (76 people, 88.4%).Conclusion: The distribution of cholelithiasis patients who underwent laparoscopic cholecystectomy in the Aloei Saboe Hospital is most common in women aged 46-55, and most patients have no history of diabetes mellitus. This finding may offer a primary data reference for further research adding the number of variables to determine the risk factors for cholelithiasis.