bluuebunny/crossref_metadata_2025_split huggingface dataset:
Differences in target estimands between different propensity score‐based weights
Authors: Austin Peter C. 
Published: May 2023

AbstractPurposePropensity score weighting is a popular approach for estimating treatment effects using observational data. Different sets of propensity score‐based weights have been proposed, including inverse probability of treatment weights whose target estimand is the average treatment effect, weights whose target estimand is the average treatment effect in the treated (ATT), and, more recently, matching weights, overlap weights, and entropy weights. These latter three sets of weights focus on estimating the effect of treatment in those subjects for whom there is clinical equipoise. We conducted a series of simulations to explore differences in the value of the target estimands for these five sets of weights when the difference in means is the measure of treatment effect.MethodsWe considered 648 scenarios defined by different values of the prevalence of treatment, the c‐statistic of the propensity score model, the correlation between the linear predictors for treatment selection and the outcome, and by the magnitude of the interaction between treatment status and the linear predictor for the outcome in the absence of treatment.ResultsWe found that, when the prevalence of treatment was low or high and the c‐statistic of the propensity score model was moderate to high, that matching weights, overlap weights, and entropy weights had target estimands that differed meaningfully from the target estimand of the ATE weights.ConclusionsResearchers using matching weights, overlap weights, and entropy weights should not assume that the estimated treatment effect is comparable to the ATE.
Preparation of ternary polyaniline@CuO−zeolite composite, discussion of characteristics, properties and their applications in supercapacitors and cationic dye adsorption
Authors: Dahou Fatima Zohra , Belardja Mohamed Sifeddine , Moulefera Imane , Sabantina Lilia , Benyoucef Abdelghani 
Published: May 2023

AbstractCopper oxide−zeolite (CuO−ZT) reinforced polyaniline (PANI) matrices were prepared by in situ oxidative polymerization and the samples were characterized by X‐ray photoelectron spectroscopy, Fourier transform infrared spectroscopy, XRD, TGA, UV–visible spectrophotometry, SEM and Brunauer–Emmett–Teller theory; the optical bandgap was also evaluated. Moreover, the synthesis and exploration of electrodes are increasingly being considered for the development of conducting‐polymer‐based supercapacitors, which has attracted significant interest in energy conversion and storage technology. Here, hybrid materials used in the preparation of the electrode materials on the capacitive properties were investigated. It is found that the PANI@CuO exhibits a high specific capacitance of 311.5 F g−1 at 1.0 A g−1 current density between 0.0 and 1.0 V compared to PANI@CuO−ZT (222.7 F g−1). Further, the PANI@CuO presented an excellent cycling stability at 1.0 A g−1 (1500 cycles; 81.9%) in a two‐electrode system. Accordingly, producing a PANI matrix on CuO presented a simple and viable way to ameliorate the capacitive performance of the supercapacitor. Conversely, the adsorptive removal of malachite green and methyl violet dyes by PANI@CuO−ZT adsorbent could be described by the pseudo‐first‐order and Temkin models. The maximum adsorptive capacity of malachite green and methyl violet dyes was 249.7 and 198.2 mg g−1, respectively. © 2023 Society of Industrial Chemistry.
Stakeholder perspectives of adaptations of a burnout intervention for special education teachers
Authors: Ruble Lisa , Love Abigail , McGrew John H. , Yu Yue , Fischer Melanie W. , Salyers Michelle P. 
Published: May 2023

AbstractThe high attrition and turnover rates of qualified special education teachers (SETs) is a significant concern exacerbated by COVID‐19. Unfortunately, there are limited studies available on research‐based interventions to decrease burnout. The purpose of this study was to describe our processes and results for adaptations and modifications of BREATHE, a burnout intervention originally developed for community mental health workers, into Burnout Reduction: Enhanced Awareness, Tools, Handouts, and Education: Evidence‐based Activities for Stress for Educators (BREATHE‐EASE) for special educators with guidance from the Framework for Reporting Adaptation and Modifications to Evidence‐Based Interventions (FRAME). We applied the FRAME within a hybrid Type 1 trial for characterizing our approach. Four focus groups (N = 30; 83% female) were conducted separately according to job title (SETs; school administrators), with semi‐structured questions tailored to each group. Emergent thematic analysis was used to identify core themes related to adaptations, and results were presented to a subset of focus group members. Modifications involved content, context, and implementation changes for the adapted intervention, with most changes identified for content. FRAME was helpful for providing a systematic approach to integrate stakeholder‐informed adaptations of a burnout intervention, addressing significant concerns of SET stress, burnout, and attrition.
Cerebral palsy and executive functions: Inhibitory control and cognitive flexibility skills
Authors: Çapa Tayyare Begüm , Gerçek Evrim , Dursun Erbil , Akçin Nur 
Published: May 2023

AbstractExecutive functions (EFs) are an umbrella term that includes various cognitive abilities (such as inhibition, planning, goal‐setting, monitoring, and shifting). There is common agreement that there are three main EFs: inhibitory control, cognitive flexibility, and working memory. Further studies have reported that compared to typically developing peers, children with cerebral palsy (CP) show deficits in EF skills. This study aims to evaluate children with CP's inhibitory control and cognitive flexibility skills. Forty children with CP between the ages of 7–13 were included in the present study. EF scores of the CP group were compared with scores of typically developing peers matched one‐to‐one by age and sex. The EF skills were evaluated with Wisconsin card sorting test (WCST), Stroop color–word test (SCWT) TBAG Form, and executive function behavior rating scale parent form (BRIEF‐P). It was determined that there was a significant difference in the WCST total trials, total errors, categories completed, and percent conceptual level responses scores (p < .05); SCWT‐TBAG scores (p < .05), and BRIEF‐P all scores (p ≤ .01) of children with CP. The results of this study suggest that children with CP are disadvantaged with EF skills in terms of inhibitory control and cognitive flexibility.
Paraprofessionals' use of classroom management in a small‐group intervention
Authors: Mesa Michael P. , Phillips Beth M. , Lonigan Christopher J. 
Published: May 2023

AbstractAlthough previous research suggests the use of classroom management strategies can support student engagement and learning, gaps in the literature still exist including the frequency of classroom management strategies in small‐group instruction. The purpose of this descriptive study was to measure the frequency of paraprofessionals' (n = 94) classroom management strategies within the context of a small‐group intervention for kindergarteners at‐risk of reading difficulties. This study contributes to the field by finding that trends described in previous studies continue to be demonstrated in this targeted instructional setting, in particular, regarding the infrequent use of praise with students at‐risk of academic failure. The results of paired‐sample sign tests suggest that when providing corrective feedback, paraprofessionals were more likely to specifically label the behavior being reprimanded. However, paraprofessionals infrequently labeled the specific behavior being reinforced when praising students.
Pediatric leukemia: What school psychologists should know
Authors: Alexandra Bobb‐Woodson , Denise Maricle 
Published: May 2023

AbstractPediatric cancer is the second leading cause of death among children ages 1–14 (Whitehead et al., 2016). Approximately 10,500 children ages 1–14 and 5090 adolescents ages 15–19 have been diagnosed with cancer in 2021 (American Cancer Society, 2021). An estimated 28% of childhood cases and 13% of adolescent patients will be diagnosed explicitly with Leukemia (American Cancer Society, 2021). Leukemia is a broad term that encompasses the malignant disease of bone marrow and other structures responsible for blood production (Olin et al., 2018). Children and adolescents experiencing pediatric leukemia often undergo treatment that produces biological, psychosocial, and cognitive impacts. Due to the occurrence of this disease in school‐aged children and the wide‐ranging consequences they face, school psychologists may be called upon to work with students and their families while they go through treatment during school‐aged years. This article will discuss pediatric leukemia, treatment options, long‐term impacts of treatment for patients, and considerations for working with children in the school system.
The impact of chemotherapy on cognitive performance post‐surgery in patients with colorectal cancer: A prospective cohort study
Authors: Dwek Marie‐Rose , Newman Stanton P. , Brini Stefano , Holder Pru , Machesney Michael , Propper David , Rixon Lorna R. , Hirani Shashivadan P. , Hurt Catherine S. 
Published: May 2023

AbstractObjectivesSubjective reports of cognitive impairment following chemotherapy are frequent in cancer patients. Objective cognitive impairment has been observed in cancer patients regardless of treatment regimen suggesting the relationship between cognitive impairment and chemotherapy is not clear cut. Little research has explored the effects of chemotherapy on cognition following surgery in colorectal cancer (CRC). The present study explored the effects of chemotherapy on cognitive performance in a sample of CRC patients.Methods136 participants were recruited into a prospective cohort study: 78 CRC patients undergoing surgery and adjuvant chemotherapy, 58 CRC patients undergoing surgery only. A battery of neuropsychological tests was administered to participants 4 weeks post‐surgery (T1), 12 weeks after first chemotherapy (T2) and 3 months after last chemotherapy (T3) or equivalent time‐points.ResultsUsing the criterion of scoring at least two standard‐deviations below the group norm on at least one neuropsychological test, 45%–55% of all CRC patients showed cognitive deficits 10 months after surgery (T3) and 14% on at least 3 tests. However, cognition did not significantly differ between patients who had chemotherapy and those who did not. A time by group interaction effect was found on the composite cognition score using multi‐level modelling suggesting a greater improvement in cognition in the surgery only group over time (p < 0.05).ConclusionsCRC patients display cognitive impairment 10 months after surgery. Chemotherapy did not worsen cognitive impairment but did appear to slow cognitive recovery relative to those undergoing surgery only. The findings demonstrate a clear need for supportive cognitive interventions for all CRC patients following treatment.
Appearance‐related psychosocial distress after facial non‐melanoma skin cancer surgery: A 1‐year prospective study
Authors: D’Hondt Valérie , Veldhuizen Inge J. , Theelen F. F. M. , Herlaar Stéphanie , Lee Erica H. , Houterman Saskia , Brinkhuizen Tjinta , Hoogbergen Maarten M. 
Published: May 2023

AbstractObjectivePatients undergoing Mohs Micrographic Surgery (MMS) for facial non‐melanoma skin cancer (NMSC) experience appearance‐related psychosocial distress due to its post‐surgical esthetic changes. However, little is known about its development over a longer follow‐up period. This study prospectively assessed appearance‐related psychosocial distress in patients undergoing MMS for facial NMSC over a 1‐year follow up period.MethodsPatients who had MMS for facial NMSC between September 2020 and October 2021 were invited to answer the FACE‐Q Skin Cancer ‐ appearance‐related psychosocial distress scale preoperatively, 2 weeks, 6 months, and 1 year after surgery.ResultsA total of 217 patients completed the questionnaire at baseline. In addition, 158 (72.8%), 139 (64.1%), and 120 (55.3%) questionnaires were successfully answered 2 weeks, 6 months, and 1 year after surgery, respectively. Patients with a peripheral lesion presented higher appearance‐related psychosocial distress scores at baseline than patients with a central lesion (p = 0.02). There was a decreasing trend in appearance‐related psychosocial distress over time, but without a significant result (baseline—2‐week; p = 0.73, 2‐week—6‐month; p = 0.80, 6‐month—1‐year; p = 0.17, baseline—1‐year; p = 0.23). Patients with secondary intention healing and graft reconstruction methods experienced more appearance‐related psychosocial distress over time than patients with primary wound closures (p = 0.03).ConclusionsPatients still experience appearance‐related psychosocial distress 1 year after MMS. These patients may benefit from targeted counseling. Additionally, predictors of more appearance‐related psychosocial distress, such as secondary intention healing and graft reconstruction methods, may benefit from additional psychological care.
Effect of a high‐fat and high‐calorie food on the pharmacokinetics of a novel, potent GABA analog HSK16149 in healthy subjects
Authors: Wu Qingqing , Zhu Huijuan , Song Rong , Zhang Mengqi , Li Fangqiong , Zeng Weifang , Wang Wei , Jia Jingying , Yu Chen , Liu Yanmei 
Published: May 2023

AbstractHSK16149 is a novel, potent gamma‐aminobutyric acid (GABA) analog for the treatment of neuropathic pain. The purpose of this study was to assess the effect of a high‐fat and high‐calorie meal on the pharmacokinetics of HSK16149 in healthy Chinese subjects. An open‐label, two‐period crossover design was applied in this study. Twenty‐six subjects were enrolled and were randomly divided into two groups: a fasted‐fed group and a fed‐fasted group, with 13 subjects in each group. Subjects took a single oral dose of 45 mg of HSK16149 under fasted or fed conditions on Day 1 and Day 4. A series of blood samples were collected for PK analysis. Safety was evaluated throughout the study by physical examinations, clinical laboratory tests, 12‐lead ECGs, vital signs, and adverse events (AEs). The parameters AUC0‐∞, AUC0‐t, and Cmax of HSK16149 were compared to assess the bioequivalence of HSK16149 under fasted and fed conditions. The geometric mean ratios (GMRs) and their 90% confidence intervals (CIs) of AUC0‐t and AUC0‐∞ under the fed condition compared with the fasted condition were 95.84% (91.94–99.90%) and 95.79% (91.89–99.84%), respectively, which were all within the bioequivalent interval (80.00–125.00%). The GMR (90% CI) of Cmax under the fed condition compared with the fasted condition was 66.04% (59.45–73.36%), which was not within the bioequivalent range (80.00–125.00%). All adverse events were transient and resolved. This study demonstrated that HSK16149 can be administered with or without food.
ROS‐responsive modified chitosan oligosaccharide nanocapsules for improving pesticide efficiency and intelligent release
Authors: Li Lin‐jie , Zhao Rui , Wang Yin‐min , Pan Shou‐he , Yu Meng , Sun Zhe , Ma Ying‐jian , Guo Xin‐yu , Xu Yong , Wang Hong‐mei , Wu Xue‐min 
Published: May 2023

AbstractBACKGROUNDSome traditional pesticide formulations are inefficient, leading to excessive use and abuse of pesticides, which in turn effects environment. Intelligent release pesticide formulations are ideal for improving pesticide utilization and persistence while reducing environmental pollution.RESULTSWe designed a benzil‐modified chitosan oligosaccharide (CO‐BZ) to encapsulate avermectin (Ave). Ave@CO‐BZ nanocapsules are prepared based on a simple interfacial method via cross‐linking of CO‐BZ with diphenylmethane diisocyanate (MDI). The Ave@CO‐BZ nanocapsules have an average particle size of 100 nm and exhibited a responsive release performance for ROS. The cumulative release rate of nanocapsules at 24 h with ROS increased by about 11.4% compared to that without ROS. The Ave@CO‐BZ nanocapsules displayed good photostability. Ave@CO‐BZ nanocapsules can penetrate root‐knot nematodes more easily and exhibited better nematicidal activity against root‐knot nematodes. The pot experiment showed that the control effect of Ave CS at low concentration was 53.31% at the initial stage of application (15 d), while Ave@CO‐BZ nanocapsules was 63.54%. Under the same conditions, the control effect of Ave@CO‐BZ nanocapsules on root‐knot nematodes was 60.00% after 45 days of application, while Ave EC was only 13.33%. The acute toxicity experiments of earthworms showed that the toxicity of nanocapsules was significantly lower than that of EC.CONCLUSIONThe ROS‐responsive nanocapsules can improve the utilization of pesticides and non‐target biosafety. This modified chitosan oligosaccharide has great potential as a bio stimuli‐responsive material, and this simple and convenient method for preparing Ave@CO‐BZ nanocapsules provides a direction for the effective utilization of pesticides. © 2023 Society of Chemical Industry.
Isoamericanin A improves lipopolysaccharide‐induced memory impairment in mice through suppression of the nicotinamide adenine dinucleotide phosphateoxidase‐dependent nuclear factor kappa B signaling pathway
Authors: Yang Yanqiu , Chen Ru , Che Yue , Yao Xiaohu , Fang Mingxia , Wang Yingjie , Zhou Di , Li Ning , Hou Yue 
Published: May 2023

AbstractAlzheimer's disease (AD) is the most frequent cause of dementia in the elderly. Isoamericanin A (ISOA) is a natural lignan possessing great potential for AD treatment. This study investigated the efficacy of ISOA on memory impairments in the mice intrahippocampal injected with lipopolysaccharide (LPS) and the underlying mechanism. Y‐maze and Morris Water Maze data suggested that ISOA (5 and 10 mg/kg) ameliorated short‐ and long‐term memory impairments, and attenuated neuronal loss and lactate dehydrogenase activity. ISOA exerted anti‐inflammatory effect demonstrating by the reduction of ionized calcium‐binding adapter molecule 1 positive cells and suppression of marker protein and pro‐inflammation cytokines expressions induced by LPS. ISOA suppressed the nuclear factor kappa B (NF‐κB) signaling pathway by inhibiting IκBα phosphorylation and NF‐κB p65 phosphorylation and nuclear translocation. ISOA inhibited superoxide and intracellular reactive oxygen species accumulation by reducing nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activation, demonstrating by suppressing NADP+ and NADPH contents, gp91phox expression, and p47phox expression and membrane translocation. These effects were enhanced in combination with NADPH oxidase inhibitor apocynin. The neuroprotective effect of ISOA was further proved in the in vitro models. Overall, our data revealed a novel pharmacological activity of ISOA: ameliorating memory impairment in AD via inhibiting neuroinflammation.
On the inverse power law‐normal model for life prediction of organic light emitting diodes
Authors: Abdul Majid Mohammed , Helal Sara , Kittaneh Omar 
Published: May 2023

AbstractIn accelerated life testing analysis with nonthermal accelerating stress, the inverse power law (IPL) is often solely merged with a particular lifetime probability distribution with a shape parameter. Although many fundamental lifetime distributions, such as the normal distribution, are excellent fits to the experimental lifetime data, they have not been considered as they lack the shape parameter. As such, this paper, for the first time, demonstrates that the shape parameter can be replaced by the coefficient of variation, allowing the use of normal distributions in this context. The work further introduces the IPL‐normal model in a rigorous mathematical setup that precisely leads to the least squares estimating equations and maximum likelihood estimates of the IPL‐normal accelerating parameters and the general coefficient of variation. The proposed model uses accelerated experimental data to successfully predict the lifetime of organic light‐emitting diodes (OLEDs) at use conditions. Based on these fundamentals, the predictions are benchmarked with prior works that were validated by market studies.
Distributed extended high‐gain observers for the generalized strict‐feedback system
Authors: Ji Yuehui , Xu Zhao , Liu Junjie , Song Yu 
Published: May 2023

AbstractTwo distributed extended high‐gain observers are studied for the generalized strict‐feedback system in presence of external disturbance. The system state dynamics are reconstructed admissibly based on the limited measured output. First, a distributed high‐gain observer is constructed to ensure the semiglobal ultimate uniform convergence of the state estimation error between the estimated state in each local observer and system state, for any prescribed initial system values. However, the dimension of the proposed distributed observer is n + 1 and the high‐gain parameter is powered up to n + 1. Therefore, a 2(n + 1)‐dimension distributed high‐gain low‐power observer is delicately designed, with the high‐gain parameter powered fixed to 2. The formulated distributed observer is easy‐implementation and the estimation error can reach fast convergence. Finally, a chaotic oscillator and a pendulum‐cart system are introduced to verify the effectiveness of the theoretical results.
Rational Loading of Linear Multi‐Site Receptors with Functional Lanthanide Containers: The Missing Link between Oligomers and Polymers
Authors: Mirzakhani Mohsen , Naseri Soroush , Egger Charlotte , Rosspeintner Arnulf , Nozary Homayoun , Piguet Claude 
Published: May 2023

AbstractAlthough metal‐containing organic polymers are becoming essential for modern applications in lighting, catalysis, and electronic devices, very little is known about their controlled metallic loading, which mainly limits their design to empirical mixing followed by characterization and often hampers rational developments. Focusing on the appealing optical and magnetic properties of 4f‐block cations, the host–guest reactions leading to linear lanthanidopolymers already display some unexpected dependence of the binding‐site affinities on the length of the organic polymer backbone: a drift usually, and erroneously, assigned to intersite cooperativity. Taking advantage of the parameters obtained for the stepwise thermodynamic loading of a series of rigid linear multi‐tridentate organic receptors with increasing length, N = 1 (monomer L1), N = 2 (dimer L2), and N = 3 (trimer L3), with [Ln(hfa)3] containers in solution (Ln = trivalent lanthanide cations, hfa− = 1,1,1,5,5,5‐hexafluoro‐pentane‐2,4‐dione anion), it is demonstrated here that the site‐binding model, based on the Potts–Ising approach, successfully predicts the binding properties of the novel soluble polymer P2N made up of nine successive binding units . An in‐depth examination of the photophysical properties of these lanthanidopolymers shows impressive UV→vis downshifting quantum yields for the europium‐based red luminescence, which can be modulated by the length of the polymeric chain.