bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of joint exposure to various ambient air pollutants during adolescence with blood pressure in young adulthood
Authors: Wu Jingjing , Li Shenxin , Duan Jingwen , Li Yalan , Wang Jie , Deng Peizhi , Meng Changjiang , Wang Wei , Yuan Hong , Lu Yao , Shen Minxue , Zhao Qiuping 
Published: July 2023

AbstractThe association of various air pollutants exposure during adolescence with blood pressure (BP) in young adulthood is uncertain. We intended to evaluate the long‐term association of individual and joint air pollutants exposure during adolescence with BP in young adulthood. This cross‐sectional study of incoming students was conducted in five geographically disperse universities in China during September and October 2018. Mean concentrations of particulate matter with diameters ≤2.5 μm (PM2.5), ≤10 μm (PM10), nitrogen dioxides (NO2), carbon monoxide (CO), sulfur dioxide (SO2), and ozone (O3) at participants’ residential addresses during 2013–2018 were collected from the Chinese Air Quality Reanalysis dataset. Generalized linear mixed models (GLM) and quantile g‐computation (QgC) models were utilized to estimate the association between individual and joint air pollutants exposure and systolic blood pressure (SBP), diastolic blood pressure (DBP), and pulse pressure (PP). A total of 16,242 participants were included in the analysis. The GLM analyses showed that PM2.5, PM10, NO2, CO, and SO2 were significantly positively associated with SBP and PP, while O3 was positively associated with DBP. The QgC analyses indicated that long‐term exposure to a mixture of the six air pollutants had a significant positive joint association with SBP and PP. In conclusion, air pollutant co‐exposure during adolescence may influence BP in young adulthood. The findings of this study emphasized the impacts of multiple air pollutants interactions on potential health and the need of minimizing pollution exposures in the environment.
Exploring appropriateness criteria for informing the total knee arthroplasty decision‐making process: An interpretive descriptive study
Authors: Pacheco‐Brousseau Lissa , Poitras Stéphane , Charette Marylène , Amor Sarah Ben , Desmeules François , Stacey Dawn 
Published: July 2023

AbstractRationalThe Hawker appropriateness criteria for total knee arthroplasty (TKA) are: osteoarthritis symptoms impacting quality of life, evidence of osteoarthritis, trial of conservative treatments, patient's realistic expectations, patient/surgeon agree benefits outweigh risks, and readiness for surgery. Little is known about the barriers and facilitators of using the Hawker et al. appropriateness criteria for TKA in clinical practice.Aims and ObjectivesExplore the barriers and facilitators to using appropriateness criteria for TKA in making decisions for adults with knee osteoarthritis.MethodsInterpretive descriptive qualitative study at an academic hospital. Purposive sampling aimed to recruit: (1) healthcare team members at all levels influencing care delivery, and (2) adults with TKA assessed at the hospital clinic. Semi‐structured interviews asked about the barriers/facilitators to using the Hawker appropriateness criteria. Data analysis consisted of inductive thematic analysis with themes mapped to the Consolidated Framework for Implementation Research domains.ResultsNine healthcare professionals and 14 adults with TKA participated and identified common barriers to using the Hawker appropriateness criteria: (a) intervention characteristics domain: difficulty to assess criteria, patients expecting healthcare professionals to decide, limited accessibility to conservative treatments; (b) individuals characteristics domain: no need to change current TKA process, clinical judgement limited to OA severity/age, implicit assessment of subjective criteria; (c) inner setting domain: TKA information received after decision made; and (d) outer setting domain: no timely access to TKA. A facilitator of use was evidence/buy‐in fosters programme changes.ConclusionBarriers to using the criteria relevant to clinical practice and the healthcare system were identified while only one facilitator was revealed. Interventions tailored to these barriers are needed to support the use of the Hawker appropriateness criteria in TKA decision‐making.
Color stability and degree of conversion of gingiva‐colored resin‐based composites
Authors: Benavides‐Reyes Cristina , Pérez María M. , Tejada‐Casado Maria , Ruiz‐López Javier , Lucena Cristina 
Published: July 2023

AbstractObjectivesTo evaluate gingiva‐colored resin‐based composites' (GCRBC) color stability and degree of conversion (DC%).MethodsEight discs (8 × 1 mm) of 20 shades of GCRBC were prepared. Color coordinates were measured against a gray background with a calibrated spectroradiometer, CIE D65 illuminant and the CIE 45°/0° geometry at baseline and after 30 days of storage in distilled water, coffee, and red wine. Color differences () between final and baseline conditions were calculated. An ATR‐FTIR spectrometer with a diamond tip was used to calculate DC%. The results were analyzed statistically using ANOVA and Tukey post‐hoc test. The level of significance was p < 0.05.ResultsDC% and color stability correlated with each other and with the GCRBC brand. DC% ranged between 43% and 96%, highest values correspond to flowable composites. All composites have experienced color changes after immersion in water, wine and coffee. However, the magnitude of the color change has varied widely depending on the immersion medium and the GCRBC. Color changes generated by the wine were, globally, greater than those induced by coffee (p < 0.001) and above the acceptability thresholds.ConclusionsThe DC% of GCRBCs is sufficient to achieve adequate biocompatibility and physicomechanical properties, but the high susceptibility to staining could compromise aesthetic long‐term results.Clinical SignificanceThe degree of conversion and the color stability of gingiva‐colored resin‐based composites correlated with each other. All composites have experienced color changes after immersion in water, wine and coffee. Color changes generated by wine were, globally, greater than those induced by coffee and above the acceptability thresholds that could compromise aesthetic long‐term results.
A Glass Bottle, A Talk, A Falling Star
Authors: Te Sahar , Sandhu Aman 
Published: July 2023

AbstractThe 13‐minute video excerpt from an artist talk, “Listen to the Voices in my Head,” delivered on December 2nd, 2022, by Sahar Te at the Alberta University of the Arts. Accompanying the video is a written response by artist and writer Aman Sandhu who was present at the talk.
Vive le Tour!? Estimating the place‐based benefits of hosting the Tour de France
Authors: Makkonen Teemu , Mitze Timo 
Published: July 2023

AbstractThe Tour de France (TdF) is one of the biggest and most recognized annual sporting events in the world. Cities and regions participate actively by hosting a stage start and/or finish, but it is unclear if there are place‐based benefits from such local engagements. We estimate the direct and spatially indirect immediate regional benefits of hosting a TdF stage using monthly tourism data for French départements during 2011–2020. Our static and dynamic panel regressions indicate that hosting a TdF stage leads to significant increases in tourist arrivals and nights spent vis‐à‐vis similar départements not hosting a stage at the same time. Results are found to be robust when we run placebo tests, matching‐based estimation to deal with regional heterogeneity and associated treatment endogeneity as well as spatially augmented estimations to account for interregional spillovers to départements not directly hosting a stage start/finish, for example, to those located along the route of a TdF stage. We use the obtained treatment estimates to discuss the regional economic impact of the TdF and their ramifications for tourism‐based regional development and event management.
Environment drives color pattern polymorphism in sand lizards beyond the Gloger's rule
Authors: Sau S. , Smolinský R. , Martínková N. 
Published: July 2023

AbstractSpecies color and color pattern vary geographically contributing to environmental tolerance of the species to the fluctuating climate. In a constantly changing environment, the population remains polymorphic, when individuals that are not acclimated to the current environment can survive adverse time periods. Factors influencing color morph frequencies in populations affect spatial variation through local adaptation, which is in turn linked to large‐scale environmental gradients. The influence of environmental factors has not been adequately studied in many polymorphic organisms where the influence of sexual selection on the persistence of polymorphisms is widely recognized. We hypothesized that different color morphs of sand lizard are distributed throughout the Palearctic depending on different environmental conditions. The goal of this study was to examine if the range of morph composition in a color polymorphic lizard can be explained by geographic and climatic variation in the Palearctic. We used publicly available data on sand lizard occurrence from the Global Biodiversity Information Facility and environmental variables from WorldClim and SEDAC databases. We categorized sand lizards' photos to 10 discrete color morphs based on color and color pattern variation. We predicted the color morph distribution using maximum entropy models. We found that variations in morph distributions were mostly related to temperature seasonality, precipitation, elevation, and anthropogenic activities. Our findings support the relationship between environmental conditions and color morph distribution, implying that environmental selection acts differently on color morphs, most likely in conjunction with sexual selection.
Sanitizing a crisis: The three dimensions of an enhanced regime of accumulation
Authors: Bernat Molina Ignasi , Cutillas Márquez Sergi 
Published: July 2023

AbstractIn many western countries the Covid crisis has evolved from a public health crisis toward an economic crisis. Spain was no exception. Crises are always key moments in the reconfiguration of the role of the state, as this takes on new domains and functions. Conceiving state's role as a triad helps us understanding its functioning. From the initial stage, state work has been intense in order to mitigate its effects. But the Spanish particularity is the specific articulation of state apparatuses. As in previous crises, Spain has deployed a significant activity to police the public order. The policing of public spaces was tailored to ensure the economic apparatuses remain unchallenged. A new mode of regulation has been established to allow an enhanced regime of capital accumulation through different financial instruments. Despite the frequent neglect of ideological state apparatuses, this paper exposes how relevant they are in moments of impasse to produce a new moral economy reassuring the hegemonic project of the elites.
Causal impacts of educational attainment on chronic liver diseases and the mediating pathways: Mendelian randomization study
Authors: Wang Yiying , Kong Lijie , Ye Chaojie , Dou Chun , Zheng Jie , Xu Min , Xu Yu , Li Mian , Zhao Zhiyun , Lu Jieli , Chen Yuhong , Wang Weiqing , Ning Guang , Bi Yufang , Wang Tiange 
Published: July 2023

AbstractBackground and AimsEducational attainment is an essential socio‐economic indicator with broad implications for lifestyle behaviour and metabolic health. We aimed to investigate the causal effect of education on chronic liver diseases and the potential mediating pathways.MethodsWe applied univariable Mendelian randomization (MR) to assess the causal associations between educational attainment and non‐alcoholic fatty liver disease (NAFLD) (cases/controls: 1578/307 576 in FinnGen; 1664/400 055 in UK Biobank), viral hepatitis (1772/307 382; 1215/403 316), hepatomegaly (199/222 728; 297/400 055), chronic hepatitis (699/301 014; 277/403 316), cirrhosis (1362/301 014; 114/400 055) and liver cancer (518/308 636; 344/393 372) using summary statistics of genome‐wide association studies from the FinnGen Study and the UK Biobank, respectively. We used two‐step MR to evaluate potential mediators and their mediation proportions in the association.ResultsMeta‐analysis of inverse variance weighted MR estimates from FinnGen and UK Biobank showed that genetically predicted 1‐SD (4.2 years) higher education was causally associated with decreased risks of NAFLD (OR: 0.48; 95%CI: 0.37–0.62), viral hepatitis (0.54; 0.42–0.69) and chronic hepatitis (0.50; 0.32–0.79), but not hepatomegaly, cirrhosis and liver cancer. Nine, two and three out of 34 modifiable factors were identified as causal mediators in the associations of education with NAFLD, viral hepatitis and chronic hepatitis, respectively, including six adiposity traits (mediation proportion: 16.5%–32.0%), major depression (16.9%), two glucose metabolism‐related traits (2.2%–15.8%) and two lipids (9.9%–12.1%).ConclusionsOur findings supported the causal protective effects of education on chronic liver diseases and outlined mediating pathways to inform prevention and intervention strategies to reduce the burden of liver diseases, especially for individuals with lower education.
Phylogeny and spatial distribution of Japanese encephalitis virus vector species in Cambodia
Authors: Dusadeepong Rutaiwan , Maquart Pierre‐Olivier , Hide Mallorie , Boyer Sebastien 
Published: July 2023

AbstractIn Southeast Asia, despite the use of Japanese encephalitis vaccines and vaccination coverage, Japanese encephalitis (JE) transmission is still a major public health issue. The main vectors of this virus are mosquitoes from the genusCulex,which diversity and density are important in Southeast Asia. The main vector species of Japanese encephalitis virus (JEV) in Cambodia belong to the Vishnui subgroup. However, their morphological identification solely based on the adult stage remains challenging, making their segregation and detection difficult.In order to identify and describe the distribution of the three main JEV vector species in Cambodia, namelyCulex vishnui,Cx. pseudovishnuiandCx. tritaeniorhynchus, mosquito samplings were carried out throughout the country in different environments. Phylogenetic analysis of thecytochrome c oxidase subunit I(coI) gene using maximum‐likelihood tree with ultrafast bootstrap and phylogeographic analysis were performed. The three mainCulexspecies are phylogenetically separated, and represent two distinct clades, one withCx. tritaeniorhynchusand the second withCx. vishnuiandCx. pseudovishnui, the latter appearing as a subgroup ofCx. vishnui. The phylogeographic analysis shows a distribution of the Vishnui subgroup on the entire Cambodian territory with an overlapped distribution areas leading to a sympatric distribution of these species. The three JEV vector species are geographically well‐defined with a strong presence ofCx. pseudovishnuiin the forest. Combined with the presence ofCx. tritaeniorhynchusand Cx. vishnuiin rural, peri‐urban, and urban areas, the presence of JEV‐competent vectors is widespread in Cambodia.
Nursing as total institution
Authors: Dillard‐Wright Jess , Jenkins Danisha 
Published: July 2023

AbstractHealthcare under the auspices of late‐stage capitalism is a total institution that mortifies nurses and patients alike, demanding conformity, obedience, perfection. This capture, which resembles Deleuze's enclosure, entangles nurses in carceral systems and gives way to a postenclosure society, an institution without walls. These societies of control constitute another sort of total institution, more covert and insidious for their invisibility (Deleuze, 1992). While Delezue (1992) named physical technologies like electronic identification badges as key to understanding these societies of control, the political economy of late‐stage capitalism functions as a total institution with no cohesive, centralized, connected material apparatus required. In this manuscript, we outline the ways in which the healthcare industrial complex demands nurse conformity and how that, in turn, operationalizes nurses in service to the institution. This foundation leads to the assertion that nursing must foster a radical imagination for itself, unbound by reality as it presently exists, in order that we might conjure more just, equitable futures for caregivers and care receivers alike. To tease out what a radical imagination might look like, we dwell in paradox: getting folks the care they need in capitalist healthcare systems; engaging nursing's deep history to inspire alternative understandings for the future of the discipline; and how nursing might divest from extractive institutional structures. This paper is a jumping‐off place to interrogate the ways institutions telescope and where nursing fits into the arrangement.
Low baseline intraspecific variation in leaf pressure‐volume traits: Biophysical basis and implications for spectroscopic sensing
Authors: Browne Marvin , Bartlett Megan K. , Henry Christian , Jarrahi Mona , John Grace , Scoffoni Christine , Yardimci Nezih Tolga , Sack Lawren 
Published: July 2023

AbstractIntra‐specific trait variation (ITV) plays a role in processes at a wide range of scales from organs to ecosystems across climate gradients. Yet, ITV remains rarely quantified for many ecophysiological traits typically assessed for species means, such as pressure volume (PV) curve parameters including osmotic potential at full turgor and modulus of elasticity, which are important in plant water relations. We defined a baseline “reference ITV” (ITVref) as the variation among fully exposed, mature sun leaves of replicate individuals of a given species grown in similar, well‐watered conditions, representing the conservative sampling design commonly used for species‐level ecophysiological traits. We hypothesized that PV parameters would show low ITVref relative to other leaf morphological traits, and that their intraspecific relationships would be similar to those previously established across species and proposed to arise from biophysical constraints. In a database of novel and published PV curves and additional leaf structural traits for 50 diverse species, we found low ITVref for PV parameters relative to other morphological traits, and strong intraspecific relationships among PV traits. Simulation modeling showed that conservative ITVref enables the use of species‐mean PV parameters for scaling up from spectroscopic measurements of leaf water content to enable sensing of leaf water potential.
Real‐time monitoring of cell surface protein arrival with split luciferases
Authors: Fischer Alexandra A. M. , Schatz Larissa , Baaske Julia , Römer Winfried , Weber Wilfried , Thuenauer Roland 
Published: July 2023

AbstractEach cell in a multicellular organism permanently adjusts the concentration of its cell surface proteins. In particular, epithelial cells tightly control the number of carriers, transporters and cell adhesion proteins at their plasma membrane. However, sensitively measuring the cell surface concentration of a particular protein of interest in live cells and in real time represents a considerable challenge. Here, we introduce a novel approach based on split luciferases, which uses one luciferase fragment as a tag on the protein of interest and the second fragment as a supplement to the extracellular medium. Once the protein of interest arrives at the cell surface, the luciferase fragments complement and generate luminescence. We compared the performance of split Gaussia luciferase and split Nanoluciferase by using a system to synchronize biosynthetic trafficking with conditional aggregation domains. The best results were achieved with split Nanoluciferase, for which luminescence increased more than 6000‐fold upon recombination. Furthermore, we showed that our approach can separately detect and quantify the arrival of membrane proteins at the apical and basolateral plasma membrane in single polarized epithelial cells by detecting the luminescence signals with a microscope, thus opening novel avenues for characterizing the variations in trafficking in individual epithelial cells.
TAGUCHI OPTIMIZATION OF WATER SAVONIUS TURBINE FOR LOW-VELOCITY INLETS USING CFD APPROACH
Authors: Al_Quraishi Mohammed Baqer Zaki Yahya 
Published: July 2023

One of the renewable energy technologies for producing electricity from moving water is the Savonius turbine. This paper optimizes the Savonius turbine performance by conducting several CFD simulations and utilizing the mixed-level Taguchi method. The quality function was first created, and then the levels and factors were determined. After analyzing the mesh and the boundary conditions, the orthogonal array was built and the CFD simulation was executed for each run. The diameter is the parameter that has the greatest influence on the hydrodynamic performance, according to the Taguchi analysis, which demonstrated the optimal combinations of the parameters in low-speed streams. The main finding was that the modified water turbine’s power of coefficient (Cp) had a 15% improvement over the original design.
Vitamin insufficiency after surgery for oesophagogastric neoplasms: a study protocol for a prospective intervention study
Authors: van der Velden Ariadne L , Vermeer Thomas A , Boerma Evert-Jan G , Belgers Eric HJ , Stoot Jan HMB , Leers Mathie PG , Sosef Meindert N , Vijgen Guy HEJ 
Published: July 2023

IntroductionOesophageal cancer (EC) and gastric cancer (GC) are among the top 10 cancers worldwide. Both diseases impact the nutritional status of patients and their Quality of Life (QoL). Preoperative malnutrition is reported in 42%–80%. However, studies investigating postoperative nutritional status are limited, and postoperative identification and treatment of micronutrient and macronutrient deficiencies are currently lacking in (inter-)national guidelines. The aim of this study is to identify and target micronutrient deficiencies after surgery for oesophagogastric neoplasms.MethodsThis is a single-centre prospective intervention trial performed in Zuyderland Medical Centre. 248 patients who underwent oesophagectomy (n=124) or (sub)total gastrectomy (n=124) from 2011 until 2022 will be included. Both groups will receive Calcium Soft Chew D3 and a multivitamin supplement (MVS) specifically developed according to the type of operation patients underwent; the oesophagectomy group will receive Multi-E and the gastrectomy group will receive Multi-G. The MVSs will be taken once daily and Calcium Soft Chew D3 two times per day. Supplementation will start after baseline measurements. At baseline (T0), blood withdrawal for micronutrient analysis and faecal elastase-1 analysis for exocrine pancreatic insufficiency (EPI) will be performed. Additionally, patients will receive questionnaires regarding QoL and dietary behaviour. After 180 days of supplementation (T1), baseline measurements will be repeated, and the supplement tolerance questionnaire will be completed. Measurements will also be conducted after 360 days (T2) and after 720 days (T3) of supplementation. The main study parameter is micronutrient deficiency (yes/no) for all measurements. Secondary parameters include occurrence of EPI (n, %), diarrhoea (n, %), steatorrhoea (n, %) or bloating (n, %), time between surgery and start of supplementation (mean in months), and QoL at all time points.Ethics and disseminationThe study was approved by the Zuyderland Medical Centre Ethics Committee, Heerlen, the Netherlands. The findings will be disseminated through scientific congresses and in peer-reviewed journals.Trial registration numberNCT05281380.