bluuebunny/crossref_metadata_2025_split huggingface dataset:
State‐of‐the‐art in Large‐Scale Volume Visualization Beyond Structured Data
Authors: Sarton J. , Zellmann S. , Demirci S. , Güdükbay U. , Alexandre‐Barff W. , Lucas L. , Dischler J. M. , Wesner S. , Wald I. 
Published: June 2023

AbstractVolume data these days is usually massive in terms of its topology, multiple fields, or temporal component. With the gap between compute and memory performance widening, the memory subsystem becomes the primary bottleneck for scientific volume visualization. Simple, structured, regular representations are often infeasible because the buses and interconnects involved need to accommodate the data required for interactive rendering. In this state‐of‐the‐art report, we review works focusing on large‐scale volume rendering beyond those typical structured and regular grid representations. We focus primarily on hierarchical and adaptive mesh refinement representations, unstructured meshes, and compressed representations that gained recent popularity. We review works that approach this kind of data using strategies such as out‐of‐core rendering, massive parallelism, and other strategies to cope with the sheer size of the ever‐increasing volume of data produced by today's supercomputers and acquisition devices. We emphasize the data management side of large‐scale volume rendering systems and also include a review of tools that support the various volume data types discussed.
Seizure characteristics and outcomes in patients with neurological conditions related to high‐risk paraneoplastic antibodies
Authors: Smith Kelsey M. , Britton Jeffrey W. , Thakolwiboon Smathorn , Chia Nicholas H. , Gupta Pranjal , Flanagan Eoin P. , Zekeridou Anastasia , Lopez Chiriboga Alfonso S. , Valencia Sanchez Cristina , McKeon Andrew , Pittock Sean J. , Dubey Divyanshu 
Published: June 2023

AbstractObjectiveSeizures are a common manifestation of paraneoplastic neurologic syndromes. The objective of this study was to describe the seizure characteristics and outcomes in patients with high‐risk paraneoplastic autoantibodies (>70% cancer association) and to determine factors associated with ongoing seizures.MethodsPatients from 2000 to 2020 with seizures and high‐risk paraneoplastic autoantibodies were retrospectively identified. Factors associated with ongoing seizures at last follow‐up were evaluated.ResultsSixty patients were identified (34 males, median age at presentation = 52 years). ANNA1‐IgG (Hu; n = 24, 39%), Ma2‐IgG (n = 14, 23%), and CRMP5‐IgG (CV2; n = 11, 18%) were the most common underlying antibodies. Seizures were the initial presenting symptom in 26 (43%), and malignancy was present in 38 (63%). Seizures persisted for >1 month in 83%, and 60% had ongoing seizures, with almost all patients (55/60, 92%) still being on antiseizure medications at last follow‐up a median of 25 months after seizure onset. Ongoing seizures at last follow‐up were associated with Ma2‐IgG or ANNA1‐IgG compared to other antibodies (p = .04), highest seizure frequency being at least daily (p = .0002), seizures on electroencephalogram (EEG; p = .03), and imaging evidence of limbic encephalitis (LE; p = .03). Death occurred in 48% throughout the course of follow‐up, with a higher mortality in patients with LE than in those without LE (p = .04). Of 31 surviving patients at last follow‐up, 55% continued to have intermittent seizures.SignificanceSeizures in the setting of high‐risk paraneoplastic antibodies are frequently resistant to treatment. Ongoing seizures are associated with ANNA1‐IgG and Ma2‐IgG, high seizure frequency, and EEG and imaging abnormalities. Although a subset of patients may respond to immunotherapy and achieve seizure freedom, poor outcomes are frequently encountered. Death was more common among patients with LE.
Turning performance measurement on its head: From the measurement of performance to the performativity of measuring
Authors: Vosselman Ed , De Loo Ivo 
Published: June 2023

AbstractThis paper develops a performativist metaphysical grounding of NPM‐based performance measurement as a radical alternative to a representationalist grounding, an alternative that turns performance measurement on its head. Performance measurement turns from an act of representation characterized by a metaphor of reflection into an ethical practice of mattering characterized by a metaphor of diffraction. In performativism, performance measurement does not (imperfectly) represent performance as a base for knowing and intervention from afar (both in terms of space and time) but issomehowperformative ofwho and what come to countin the world. Its exclusionary character makes it an inherently ethical practice. We contrast a performativist grounding of performance measurement with a representationalist grounding and rework concepts of responsibility and accountability. We illustrate a performativist grounding of performance measurement with examples from academia and healthcare and provide a direction for future research.
A comparative study of the fatigue behavior of Ti‐6Al‐4V circular lattices using numerical and experimental methods
Authors: Walker Peter , ElSayed Mostafa S. A. , Kabir Abu Syed 
Published: June 2023

AbstractLattice materials are a subset of cellular solids with a periodic microstructure and are of interest in a number of applications because of their potential weight‐saving properties. In this study, circular lattices are machined out of plates made of Ti‐6Al‐4V and fatigue tested to generate an S–N curve. These results are compared to a FEM with fatigue data based on MIL‐HDBK‐5H. A good agreement with the FEM was found, suggesting that the fatigue life of lattices can be modeled without specifically detailed fatigue data. The model accurately predicted the point of failure in most of the lattice specimens and was within 4% of the scatter band. Fractographic analysis showed significant shear features in the fracture surfaces, indicating a rapid shear fracture is likely the dominant mode of failure. Finally, the relationship between equivalent stress and relative density was determined using a variety of optimization schemes.
Compositional shifts of alpine plant communities across the high Andes
Authors: Cuesta F. , Carilla J. , LLambí L. D. , Muriel P. , Lencinas M. V. , Meneses R. I. , Feeley K. J. , Pauli H. , Aguirre N. , Beck S. , Bernardi A. , Cuello S. , Duchicela S. A. , Eguiguren P. , Gamez L. E. , Halloy S. , Hudson L. , Jaramillo R. , Peri P. L. , Ramírez L. A. , Rosero‐Añazco P. , Thompson N. , Yager K. , Tovar C. 
Published: June 2023

AbstractAimClimate change is transforming mountain summit plant communities worldwide, but we know little about such changes in the High Andes. Understanding large‐scale patterns of vegetation changes across the Andes, and the factors driving these changes, is fundamental to predicting the effects of global warming. We assessed trends in vegetation cover, species richness (SR) and community‐level thermal niches (CTN) and tested whether they are explained by summits' climatic conditions and soil temperature trends.LocationHigh Andes.Time periodBetween 2011/2012 and 2017/2019.Major taxa studiedVascular plants.MethodsUsing permanent vegetation plots placed on 45 mountain summits and soil temperature loggers situated along a ~6800 km N‐S gradient, we measured species and their relative percentage cover and estimated CTN in two surveys (intervals between 5 and 8 years). We then estimated the annual rate of changes for the three variables and used generalized linear models to assess their relationship with annual precipitation, the minimum air temperatures of each summit and rates of change in the locally recorded soil temperatures.ResultsOver time, there was an average loss of vegetation cover (mean = −0.26%/yr), and a gain in SR across summits (mean = 0.38 species m2/yr), but most summits had significant increases in SR and vegetation cover. Changes in SR were positively related to minimum air temperature and soil temperature rate of change. Most plant communities experienced shifts in their composition by including greater abundances of species with broader thermal niches and higher optima. However, the measured changes in soil temperature did not explain the observed changes in CTN.Main conclusionsHigh Andean vegetation is changing in cover and SR and is shifting towards species with wider thermal niche breadths. The weak relationship with soil temperature trends could have resulted from the short study period that only marginally captures changes in vegetation through time.
Bodily secret(ion)s: Ulrike Draesner'sgedächtnisschleifen(1995)
Authors: de Rivera Catrina 
Published: June 2023

AbstractFor Ulrike Draesner, there are clear parallels between West Germany in the 1950s and Germany during the years following reunification. Taking as its starting point Draesner's remark that memory must be viewed as a construct, this article explores embodied intergenerational memory in her debut poetry volumegedächtnisschleifen(1995).gedächtnisschleifenhas been commonly read alongside the poetry of Durs Grünbein, Thomas Kling, and other post‐Wende writers who represent divided Berlin as an opened, emaciated body. This article, however, takes a different angle, arguing thatgedächtnisschleifenrenders the body as a memory apparatus: Memory takes on the quality of a physical force or secretion, passed among bodies and across generations. Moreover, this article contends that Draesner reflects on and negotiates the role of third‐generation poetry vis‐à‐vis Germany's Nazi past.
In vitro, ex vivo and clinical approaches to evaluate the potential effect of Gentiana lutea extract on skin
Authors: Berthon Jean‐Yves , Cabannes Magalie , Bouton Carine , Carre Maude , Bridon Emilie , Filaire Edith 
Published: June 2023

AbstractBackgroundDark circles affect subjects of all ages and in all skin types. They can be treated by various methods, particular by topical solutions. This investigation was directed towards exploring the effect of gentiopicroside (GP) on the skin around the eyes. For this, an extract of Gentiana lutea (GIE) containing GP (65% by dry matter) was evaluated on oxidant and angiogenesis parameters using in vitro and ex‐vivo studies. A clinical experimentation was also realized.MethodsThe effect of GIE at different concentrations on antioxidant gene was evaluated in vitro by RT‐qPCR after treatment of NHDF. The effect of 2.93 μg mL−1 GIE on the release of VEGF‐A and VEGF‐C by NHDF was also studied. The effect of 87.9 μg mL−1 GIE was also evaluated on pseudotube formation in a coculture system of normal dermal microvascular endothelial cells (HMVEC‐d)‐NHDF stimulated or not with VEGF as pro‐angiogenic factor. Prior to these assays, preliminary cytotoxicity assays were performed using a standard WST‐8 reduction assay. The expressions of carboxymethyl‐lysine and glyoxalase‐1 were quantified on skin explants topically treated with 147 μg mL−1 GIE in basal and UVA‐irradiated conditions. A clinical study was conducted in 22 subjects using topical twice daily for 14 days on eye area (split‐face application: cream containing 147 μg mL−1 GIE versus placebo). 3D image acquisition and skin colour measurement were performed at D0 and D14.ResultsTreatment of GIE upregulated the gene expression of NFE2L2 and downregulated the expression of CXCL8. GIE targeted AGEs pathways and reduced the formation of pseudotubes. A total of 147 μg mL−1 GIE gel cream significantly reduced significantly the average roughness and relief of the upper eyelid skin as well as the redness of dark circles after 14 days of application.ConclusionBy acting on the pathway of AGEs, VEGF‐A and VEFG‐C, GIE seems to allow a rejuvenation of the skin resulting, among others, in a decrease in redness. It now would be interesting to evaluate the efficacy of GIE on skin around eyes microbiota, antibacterial gentiopicroside property being well‐established.
Barriers to accessing and receiving antenatal care: Findings from interviews with Australian women experiencing disadvantage
Authors: Penman Sarah V. , Beatson Ruth M. , Walker Elizabeth H. , Goldfeld Sharon , Molloy Carly S. 
Published: June 2023

AbstractAimTo identify the barriers associated with inadequate antenatal attendance by disadvantaged women in Australia and to further explore how these barriers are experienced by this population group.DesignA qualitative descriptive study utilizing semi‐structured interviews and thematic analysis.MethodsInterviews were conducted with 11 pregnant women who self‐identified as experiencing disadvantage, purposively sampled from a local government area of Victoria, Australia, characterized by socio‐economic disadvantage. Data were collected from February to July 2019.ResultsStudy participants reported a range of barriers to receiving timely and adequate antenatal care (ANC). For several women, a combination of personal (e.g., emotions, knowledge), health service provision (e.g., limited access to continuity of care provider and continuity of information, inflexible scheduling, difficulty travelling, staff attitudes), and broader social‐contextual factors (e.g., financial situation, language, cultural norms) were ultimately insurmountable. Whereas some barriers were experienced as hassles or annoyances, others were unacceptable, overwhelming, or humiliating.ConclusionWomen experiencing disadvantage in Australia value ANC but face multiple and complex barriers that undermine timely and regular access.Implications for the Profession and/Patient CareA wide range of strategies targeting barriers across multiple levels of the social‐ecological environment are required if ANC attendance rates are to improve and ultimately redress existing health disparities. Various continuity of care models are well‐placed to address many of the identified barriers and should be made more accessible to women, and particularly those women experiencing disadvantage.ImpactAntenatal care appointments promote the health of women and their babies during pregnancy, but for many women, particularly those experiencing disadvantage, access is delayed or inadequate. ANC providers play a critical role in facilitating timely and adequate care. Health service practitioners and management, and health services policymakers need to understand the complexity of the barriers women encounter. These stakeholders can utilize the findings reported herein to develop more effective strategies for overcoming multiple and multi‐level barriers.Reporting MethodThe study is reported in accordance with the relevant EQUATOR guidelines: the standards for reporting qualitative research (SRQR) and consolidated criteria for reporting qualitative research (COREQ).Patient or Public ContributionNo patient or public contribution.
Postponement of elective cardiac surgery: A prospective observational analysis of anxiety, depression, social support and clinical complications
Authors: Spindler Helle , Thorup Charlotte Brun , Nøhr Dorte , Andreasen Jan Jesper 
Published: June 2023

AbstractAimsTo investigate patients' psychological reactions to postponement of elective cardiac surgery, and whether postponement was associated with increased complications post‐operative and while waiting.DesignA single‐centre observational prospective cohort study.MethodsAll adult patients referred for elective cardiac surgery during the study period were considered for inclusion. Psychological data were collected using a survey distributed to patients prior to surgery and at 6 months post‐operative. Clinical data were obtained from patient records.ResultsA total of 83 postponed and 132 non‐postponed patients were included. Postponed patients displayed more avoidance behaviour, but only immediately before surgery. Postponed patients maintained their satisfaction with perceived social support, whereas non‐postponed patients became more dissatisfied over time. Waiting 0–14 days was associated with increased symptoms of depression before surgery compared to non‐postponed patients or those waiting more than 14 days. Surgical complications were the same in both groups. No patients experienced aggravation of their disease leading to urgent or emergent surgery while waiting for surgery. Hospital‐related reasons were the most common cause for postponement of surgery.ConclusionPostponement of selected patients is not associated with increased risk of psychological distress or complications related to the patient's disease.Reporting MethodStrengthening the Reporting of Observational Studies in Epidemiology (STROBE).Implications for Patient CarePre‐ and post‐psychological interventions may be relevant to consider in relation to elective cardiac surgery as it has been shown to positively affect outcome. Organisational/hospital‐related reasons are still very common causes for postponement of elective surgeries, and hospital administrations should focus upon eliminating/decreasing this.Public ContributionQuestionnaires filled by patients were used to understand an association between postponement of cardiac surgery and psychological distress.
The properties of contemporary money
Authors: Hull Isaiah , Sattath Or 
Published: June 2023

AbstractThe properties of money commonly referenced in the economics literature were originally identified by Jevons and Menger in the late 1800s and were intended to describe physical currencies, such as commodity money, metallic coins, and paper bills. In the digital era, many non‐physical currencies have either entered circulation or are under development, including demand deposits, cryptocurrencies, stablecoins, central bank digital currencies, in‐game currencies, and quantum money. These forms of money have novel properties that have not been studied extensively within the economics literature, but may ultimately determine which currencies prevail in the forthcoming era of currency competition. This review makes the first exhaustive attempt to identify and organize all properties of physical and digital forms of money. It examines both the economics and computer science literatures and categorizes properties within an expanded version of the canonical Jevons–Menger framework.
Narrow‐diameter versus regular‐diameter dental implants for mandibular overdentures: A systematic review and meta‐analysis
Authors: Park Jin‐Hong , Shin Sang‐Wan , Lee Jeong‐Yol 
Published: June 2023

AbstractPurposeThe aim of this systematic review was to compare treatment outcomes in terms of implant survival rate, marginal bone loss, and patient‐reported outcome measures (PROMs) between narrow‐diameter implants and regular‐diameter implants (RDIs) for mandibular implant overdentures (MIOs).MethodsThis study was based on the methodology adapted as per Cochrane. Medline, Embase, the Cochrane Central Register of Controlled Trials, Web of Science, and Scopus were searched for pertinent studies published by July 22, 2022. Outcome parameters included in this meta‐analysis were implant survival rate, marginal bone loss, visual analogue scale score for patient satisfaction, and value of oral health impact profile.ResultsA total of 782 non‐duplicate articles and 83 clinical study registrations were identified from database and hand searches, of which 26 were eligible for full‐text searches. Finally, 12 publications reporting on 8 independent studies were included in this review. In the meta‐analysis, implant survival rate and marginal bone loss did not significantly differ between narrow‐diameter implants and RDIs. Regarding RDIs, narrow‐diameter implants were associated with significantly better outcomes in general patient satisfaction and oral health‐related quality of life than RDIs for mandibular overdentures.ConclusionsNarrow‐diameter implants have competitive treatment outcomes compared to RDIs in terms of implant survival rate, marginal bone loss, and PROMs. [Correction added on July 21, 2023, after first online publication: The abbreviation RDIs was changed to PROMs in the preceding sentence.] Thus, narrow‐diameter implants might be an alternative treatment option for MIOs in situations with limited alveolar bone volume.
Processes triggered in guanine quadruplexes by direct absorption of UV radiation: From fundamental studies toward optoelectronic biosensors
Authors: Markovitsi Dimitra 
Published: June 2023

AbstractGuanine quadruplexes (GQs) are four‐stranded DNA/RNA structures exhibiting an important polymorphism. During the past two decades, their study by time‐resolved spectroscopy, from femtoseconds to milliseconds, associated to computational methods, shed light on the primary processes occurring when they absorb UV radiation. Quite recently, their utilization in label‐free and dye‐free biosensors was explored by a few groups. In view of such developments, this review discusses the outcomes of the fundamental studies that could contribute to the design of future optoelectronic biosensors using fluorescence or charge carriers stemming directly from GQs, without mediation of other molecules, as it is the currently the case. It explains how the excited state relaxation influences both the fluorescence intensity and the efficiency of low‐energy photoionization, occurring via a complex mechanism. The corresponding quantum yields, determined with excitation at 266/267 nm, fall in the range of (3.0–9.5) × 10−4 and (3.2–9.2) × 10−3, respectively. These values, significantly higher than the corresponding values found for duplexes, depend strongly on certain structural factors (molecularity, metal cations, peripheral bases, number of tetrads …) which intervene in the relaxation process. Accordingly, these features can be tuned to optimize the desired signal.
Mission risk control via joint optimization of sampling and abort decisions
Authors: Yang Li , Wei Fanping , Qiu Qingan 
Published: June 2023

AbstractInformation‐driven mission abort is an effective way to control the failure risk of safety‐critical systems during mission executions. We investigate the optimal sampling and mission abort decisions of partially observable safety‐critical systems, where the underlying system health state can only be revealed by sampling. In contrast to previous studies, we employ partial health information to jointly determine: (a) whether to execute sampling, and (b) when to abort the mission in a dynamic manner, so as to minimize the expected total cost incurred by sampling, mission failure, and system malfunction. Dynamic sampling and mission abort policies are devised following the belief state, whose optimization model is cast into the framework of a partially observable Markov decision process. Some structural insights with regard to the value function, control limit selection, and optimality existence are presented. The performance of the proposed sampling and abort policy is tested by numerical experiments, which are proved to outperform other heuristic abort policies in mission loss control.