bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mental Health and well-being During the COVID-19 Pandemic and After the Russian Invasion of Ukraine
Authors: Pavlova Iuliia , Rogowska Aleksandra M. , Zhang Stephen X. 
Published: August 2023

AbstractThe study compared the mental health of university students during the COVID-19 pandemic and the Russian invasion of Ukraine. A repeated online cross-sectional study was performed twice among university students in Ukraine: in November 2020 (Pre-war sample, n = 752) and September-October 2022 (During-war sample, n = 862). The survey measured life satisfaction (SWLS), perceived stress (PSS-10), anxiety (GAD-7), and depression (PHQ-9). Stress, anxiety, and life satisfaction levels were similar during the war and pandemic, while symptoms of depression decreased during the war, compared to the pandemic. Network analysis showed that anxiety has a crucial effect on depression and stress, and stress is most closely related to life satisfaction. The association of life satisfaction with anxiety and depression disappeared in wartime, in contrast to the pandemic. The priority of prevention and intervention programs in wartime Ukraine should focus on anxiety as the most influential factor in other mental health and well-being problems. The results showed high resistance and adaptation to war conditions among university students in Ukraine.
The evolving role of reirradiation in the management of recurrent brain tumors
Authors: De Pietro Raffaella , Zaccaro Lucy , Marampon Francesco , Tini Paolo , De Felice Francesca , Minniti Giuseppe 
Published: August 2023

AbstractDespite aggressive management consisting of surgery, radiation therapy (RT), and systemic therapy given alone or in combination, a significant proportion of patients with brain tumors will experience tumor recurrence. For these patients, no standard of care exists and management of either primary or metastatic recurrent tumors remains challenging.Advances in imaging and RT technology have enabled more precise tumor localization and dose delivery, leading to a reduction in the volume of health brain tissue exposed to high radiation doses. Radiation techniques have evolved from three-dimensional (3-D) conformal RT to the development of sophisticated techniques, including intensity modulated radiation therapy (IMRT), volumetric arc therapy (VMAT), and stereotactic techniques, either stereotactic radiosurgery (SRS) or stereotactic radiotherapy (SRT). Several studies have suggested that a second course of RT is a feasible treatment option in patients with a recurrent tumor; however, survival benefit and treatment related toxicity of reirradiation, given alone or in combination with other focal or systemic therapies, remain a controversial issue.We provide a critical overview of the current clinical status and technical challenges of reirradiation in patients with both recurrent primary brain tumors, such as gliomas, ependymomas, medulloblastomas, and meningiomas, and brain metastases. Relevant clinical questions such as the appropriate radiation technique and patient selection, the optimal radiation dose and fractionation, tolerance of the brain to a second course of RT, and the risk of adverse radiation effects have been critically discussed.
Graphical Abstract
Guaranteeing Trade in a Severe Crisis: Cash Collateral Over Bank Guarantees
Authors: Kotidis Antonis , MacDonald Margaux , Malliaropulos Dimitris 
Published: August 2023

AbstractBanks guarantee international trade through letters of credit. This paper analyzes what happens to trade when the critical role of banks as trade guarantors is compromised. Using the case of the Greek capital controls in 2015, the events around which led to a massive loss of confidence in the domestic banking system, we show that firms whose operations were more dependent on domestic banks suffered a steep decline in imports and, subsequently, exports. This operated through letters of credit, which during the capital controls period had to be backed by firms’ own cash collateral rather than the bank guarantee. As a result, cash-poor firms imported relatively less. Public intervention to guarantee transactions is shown to help mitigate some of the decline in imports.
Developing an Evaluation Rubric for Planning and Assessing SSI-Based STEAM Programs in Science Classrooms
Authors: Mang Ha My Anna , Chu Hye-Eun , Martin Sonya N. , Kim Chan-Jong 
Published: August 2023

AbstractThis multi-phase study designed a program evaluation rubric which used a qualitative rating system to help teachers identify key learning goals, dimensions, and principles related to the socio-scientific issues (SSI)-based science, technology, engineering, arts and mathematics (STEAM) approach for science education. This rubric contains 37 criteria that address one or more key principles of the SSI-based STEAM approach embedded in a 6E inquiry-based instructional model. It is organised into seven evaluation categories: (1) learning outcomes, (2) engage, (3) explain, (4) explore, (5) elaborate, (6) evaluate, and (7) enact. The newly developed rubric was used to evaluate six different climate change programs to determine whether it could measure the intended dimensions and principles and to assess its applicability across varying contexts. This research has implications for providing a tool for teachers to plan and design SSI-based STEAM programs.
Trajectories of Unpaid Labour and the Probability of Employment Precarity and Labour Force Detachment Among Prime Working-Age Australian Women
Authors: Ervin Jennifer , Taouk Yamna , Hewitt Belinda , King Tania 
Published: August 2023

AbstractWorldwide, women are over-represented in precarious and insecure employment arrangements. Importantly, the high unpaid labour demands women experience over the life course compromise paid labour force participation for women. This study explores the way different trajectories of time spent in unpaid labour throughout women’s prime working and child-rearing years (from baseline age of 25–35 yrs to 42–52 yrs) are associated with indicators of precarious employment and labour force detachment later in life. We applied group-based trajectory modelling to 17 waves (2002–2018) of data from the Household Income and Labour Dynamics in Australia survey to identify trajectories in unpaid labour. We then examined associations between these estimated trajectories and employment outcomes in wave 19 (2019). Our study shows that chronic exposure to high amounts of unpaid labour over prime working-age years (compared to lower exposure levels) increases women’s probability of precarious employment and labour force detachment later in prime working life. This provides evidence that ongoing inequity in the division of unpaid labour has considerable long-term implications for gender inequality in the paid labour force, and underscores the importance of urgently addressing how men and women share and prioritise time across both paid and unpaid labour domains.
Toward Planetary Health Ethics? Refiguring Bios in Bioethics
Authors: Anderson Warwick 
Published: August 2023

AbstractIn responding to perceived crises—such as the COVID-19 pandemic—in routinized ways, contemporary bioethics can make us prisoners of the proximate. Rather, we need bioethics to recognize and engage with complex configurations of global ecosystem degradation and collapse, thereby showing us paths toward co-inhabiting the planet securely and sustainably. Such a planetary health ethics might draw rewardingly on Indigenous knowledge practices or Indigenous philosophical ecologies. It will require ethicists, with other health professionals, to step up and become public advocates for environmental sustainability. The COVID-19 pandemic should be seen as opening a portal to planetary health ethics or ecologized bioethics.
Casting Justice Before Swine: Late Mediaeval Pig Trials as Instances of Human Exceptionalism
Authors: Gins Sven 
Published: August 2023

AbstractIn recent years, several cases about the legal personhood of nonhuman animals garnered global attention, e.g. the recognition of ‘basic rights’ for the Argentinian great apes Sandra and Cecilia. Legal scholars have embraced the animal turn, blurring the once sovereign boundaries between persons and objects, recognising nonhuman beings as legal subjects. The zoonotic origins of the Covid-19 pandemic stress the urgency of establishing ‘global animal law’ and deconstructing anthropocentrism. To this end, it is vital to also consider the extensive premodern legal history that humans share with other animals. Over 200 so-called animal trials have been documented in premodern Europe. In these proceedings, certain nonhuman animals—particularly domestic pigs—were prosecuted, often resulting in their capital punishment or anathema. This paper takes a history of ideas approach to these historical instances where Western philosophy of law and philosophical anthropology intersect, problematising the notion that such trials constitute wholesome precedents of the kind of legal personhood presently debated in jurisprudence. My counter-hegemonic analysis of the legal prosecution and execution of several pigs in fifteenth-century France demonstrates that late mediaeval notions of criminality transcended the alleged human-nonhuman divide whilst reaffirming and reifying human distinctiveness. I propose that pig trials were local laboratories where Christian communities reflected upon the natural hierarchy of God’s creation. Ensuing the apparent breach of the prescribed boundaries of nature, these communities renegotiated and re-naturalised everyday interspecies sociability by utilising the offending animals to exemplify particular norms about what it means to be human, generally to the animals’ detriment.
Answering Divine Love: Human Distinctiveness in the Light of Islam and Artificial Superintelligence
Authors: Çelik Yusuf 
Published: August 2023

AbstractIn the Qur’an, human distinctiveness was first questioned by angels. These established denizens of the cosmos could not understand why God would create a seemingly pernicious human when immaculate devotees of God such as themselves existed. In other words, the angels asked the age-old question: what makes humans so special and different? Fast forward to our present age and this question is made relevant again in light of the encroaching arrival of an artificial superintelligence (ASI). Up to this point in history, humans have exceeded other creatures in various respects; now a possibility has arisen that another entity, namely ASI, will exceed humans at least on the level of intelligence and power. In relation to the age of angels, pre-modern Sunni exegesis construed human distinctiveness along the axes of reproductive knowledge and stewardship. Both brittle, distinguishing markers will disappear in the age of the ASI. Conversely, a more resilient and creative Islamic response can be derived from Ibn al-ʿArabī’s (d. 1240) views on God and the imago Dei. Inspired by the Akbarian perspective, this paper construes human distinctiveness in relation to a capacity to expansively respond to God’s love to be recognized, a response that relies on (a) imitating divine virtues that operate in counterintuitive and illogical ways, and (b) exhibiting fragility and lack rather than exceptionalism. ASI, while responding already in part to God’s love, needs to make strides towards these traits before it can answer divine love as commensurately as humans can.
Die Lohnlücke in der Zeitarbeit
Authors: Bachmann Ronald , Flores Fernanda Martínez , Rulff Christian 
Published: August 2023

ZusammenfassungDie Lohnlücke zwischen Personen, die innerhalb und außerhalb der Zeitarbeit beschäftigt sind, wird in Deutschland auf Grundlage verschiedener Datensätze berechnet, was teilweise zu sehr unterschiedlichen Ergebnissen führt. Der vorliegende Artikel untersucht die Lohnlücke in der Zeitarbeit daher anhand zweier Datensätze, den Integrierten Erwerbsbiografien (IEB) des Instituts für Arbeitsmarkt- und Berufsforschung der Bundesagentur für Arbeit und der Verdienststrukturerhebung (VSE) des Statistischen Bundesamtes. Hierzu wird die Lohnlücke auf Basis der beiden Mikrodatensätze mithilfe verschiedener ökonometrischer Verfahren analysiert.Die Ergebnisse der Studie zeigen, dass beim Vergleich von öffentlichen Statistiken auf eine Vergleichbarkeit der zugrundeliegenden Stichprobe geachtet werden sollte. Die Lohnlücke bei den Monatslöhnen ist bei Verwendung von IEB-Daten etwas größer als bei VSE-Daten, was auf Unterschiede in der Zusammensetzung der Stichprobe zurückzuführen ist. Die ökonometrische Analyse der Monatslöhne ergibt für beide Datensätze, dass die bereinigte Lohnlücke, d. h. die Lohnlücke nach Kontrolle für beobachtbare Charakteristika, deutlich geringer ausfällt als die unbereinigte Lohnlücke. Eine zusätzliche Analyse der Stundenlöhne auf Grundlage der VSE zeigt, dass die bereinigte Lohnlücke nahe null liegt. Dies deutet darauf hin, dass die Arbeitszeit eine wichtige Rolle für die Lohnlücke spielt.
Metformin as a promising target for DPP4 expression: computational modeling and experimental validation
Authors: El-Arabey Amr Ahmed , Zhang Haiyan , Abdalla Mohnad , Al-Shouli Samia T. , Alkhalil Samia S. , Liu Yi 
Published: August 2023

AbstractMetformin is a regularly prescribed and low-cost generic medication. Metformin has been proposed as a target for Dipeptidyl-peptidase 4 (DPP4) expression in various clinical disorders. We provide insilco investigations on molecular docking and dynamic modeling of metformin and DPP4 potential interactions. Moreover, we conducted bioinformatic studies to highlight the clinical significance of DPP4 expression and mutation in various types of malignancies, as well as the invasion of different immune cells into the tumor microenvironment. We believe the present proposal’s findings have crucial implications for understanding how metformin may confer health advantages by targeting DPP4 expression in malignancies.
Graphical abstract
Ethnic profiling of organised crime? A tendency of mafia-cation in the Netherlands
Authors: Eski Yarin , Sergi Anna 
Published: August 2023

AbstractThis article will explore how the current narratives (and corresponding changes) in Dutch organised crime policing relate to ethnic profiling of minorities in the Netherlands. It will do so by developing a theoretically informed narrative understanding of what we would like to conceptualise as ethnic profiling of organised crime (in the Netherlands), digging deeper into the connection between the role of ethnicity in organised crime studies inasmuch as it relates to the history of the mafia concept and, even further, lingering colonialism in law-and-order approaches. By focusing on (assumed) socio-historical connections between Italy, mafia and organised crime and on the social construction of Italian mafia as organised crime, based on narrative criminology, this article discursively and interpretatively understands the dominant and hidden Dutch narratives on (policing) organised crime. The discovered narratives will be critically discussed in light of the juxtaposition between mafias and ethnic organised crime and post-colonial implications.
The effectiveness of an instagram intervention targeted at men to reduce body dissatisfaction
Authors: Stiff Chris , Cutts Megan 
Published: August 2023

AbstractInstagram is a hugely popular social media website; however, research has suggested that continued use of the site may lead to increased body dissatisfaction and lower body esteem. Materials intended to reduce these effects are available, but these often focus more on thinness and are intended for use by females. Male users tend to focus more on muscularity and leanness, and so these materials may not fully address male body image issues. In this paper, we created and tested materials intended to address this gap. These materials used two principles; media literacy, which educates users about the veracity of the images they see, and cognitive restructuring, which trains user to recognise unfavourable social comparisons they may make about themselves. Across two experimental studies (study 1 N = 192; study 2 N = 301), we found these materials were effective. Participants reported greater body image esteem, and lower body dissatisfaction after viewing materials. Moreover, they seemed to operate on increasing scepticism regarding the realism of images on social media. Narcissism as an individual difference moderated these effects, showing that high narcissism precluded the need for intervention because such individuals were unaffected by Instagram exposure. Ideas for future studies, including a forthcoming longitudinal examination of these effects are then discussed.
Lactobacillus rhamnosus GG Regulates Host IFN-I Through the RIG-I Signalling Pathway to Inhibit Herpes Simplex Virus Type 2 Infection
Authors: Wang Jingyu , Huang Mei , Du Yuqi , Chen Haoming , Li Zixiong , Zhai Taiyu , Ou Zihao , Huang Yiyi , Bu Fan , Zhen Haojun , Pan Ruoru , Wang Yubing , Zhao Xiaohan , Situ Bo , Zheng Lei , Hu Xiumei 
Published: August 2023

AbstractNumerous recent studies have demonstrated that the commensal microbiota plays an important role in host immunity against infections. During the infection process, viruses can exhibit substantial and close interactions with the commensal microbiota. However, the associated mechanism remains largely unknown. Therefore, in this study, we explored the specific mechanisms by which the commensal microbiota modulates host immunity against viral infections. We found that the expression levels of type I interferon (IFN-I) and antiviral priming were significantly downregulated following the depletion of the commensal microbiota due to treatment with broad-spectrum antibiotics (ABX). In addition, we confirmed a unique molecular mechanism underlying the induction of IFN-I mediated by the commensal microbiota. In vivo and in vitro experiments confirmed that Lactobacillus rhamnosus GG (LGG) can suppress herpes simplex virus type 2 (HSV-2) infection by inducing IFN-I expression via the retinoic acid-inducible gene-I (RIG-I) signalling pathway. Therefore, the commensal microbiota-induced production of IFN-I provides a potential therapeutic approach to combat viral infections. Altogether, understanding the complexity and the molecular aspects linking the commensal microbiota to health will help provide the basis for novel therapies already being developed.
Graphical Abstract
Protonentherapie voor seminoma testis
Authors: Sinnige Peter F. , Reynders Kobe J. , Bakker Pauline A. C. 
Published: August 2023

SamenvattingSeminoma testis wordt gekenmerkt door een hoge ziektevrije en algehele overleving. Bij beperkt lymfogeen gemetastaseerde ziekte is para-aortale en para-iliacale radiotherapie een curatieve behandeloptie. Het belangrijkste nadeel van deze behandeling is het verhoogde risico op secundaire maligniteiten nadien. Dit lijkt voornamelijk te gelden voor tumoren van de maag, pancreas, nieren en blaas. Het risico op tumorinductie is afhankelijk van de bestralingsdosis die op het orgaan komt. Met protonentherapie is het mogelijk om de dosis op deze organen te verminderen ten opzichte van fotonentherapie. Vanaf maart 2022 wordt deze behandeling aangeboden in de drie Nederlandse protonencentra. Dit artikel beschrijft de indicaties en onderbouwing voor het gebruik van protonentherapie bij patiënten met een seminoom. Daarnaast worden enkele technische aspecten besproken.
Association of tyrosine hydroxylase 01 (TH01) microsatellite and insulin gene (INS) variable number of tandem repeat (VNTR) with type 2 diabetes and fasting insulin secretion in Mexican population
Authors: Berumen J. , Orozco L. , Gallardo-Rincón H. , Juárez-Torres E. , Barrera E. , Cruz-López M. , Benuto R. E. , Ramos-Martinez E. , Marin-Madina M. , Alvarado-Silva A. , Valladares-Salgado A. , Peralta-Romero J. J. , García-Ortiz H. , Martinez-Juarez L. A. , Montoya A. , Alvarez-Hernández D. A. , Alegre-Diaz J. , Kuri-Morales P. , Tapia-Conyer R. 
Published: August 2023

Abstract
Purpose
A variable number of tandem repeats (VNTR) in the insulin gene (INS) control region may be involved in type 2 diabetes (T2D). The TH01 microsatellite is near INS and may regulate it. We investigated whether the TH01 microsatellite and INS VNTR, assessed via the surrogate marker single nucleotide polymorphism rs689, are associated with T2D and serum insulin levels in a Mexican population.

Methods
We analyzed a main case–control study (n = 1986) that used univariate and multivariate logistic regression models to calculate the risk conferred by TH01 and rs689 loci for T2D development; rs689 results were replicated in other case–control (n = 1188) and cross-sectional (n = 1914) studies.

Results
TH01 alleles 6, 8, 9, and 9.3 and allele A of rs689 were independently associated with T2D, with differences between sex and age at diagnosis. TH01 alleles with ≥ 8 repeats conferred an increased risk for T2D in males compared with ≤ 7 repeats (odds ratio, ≥ 1.46; 95% confidence interval, 1.1–1.95). In females, larger alleles conferred a 1.5-fold higher risk for T2D when diagnosed ≥ 46 years but conferred protection when diagnosed ≤ 45 years. Similarly, rs689 allele A was associated with T2D in these groups. In males, larger TH01 alleles and the rs689 A allele were associated with a significant decrease in median fasting plasma insulin concentration with age in T2D cases; the reverse occurred in controls.

Conclusion
Larger TH01 alleles and rs689 A allele may potentiate insulin synthesis in males without T2D, a process disabled in those with T2D.
TCANet: three-stream coordinate attention network for RGB-D indoor semantic segmentation
Authors: Jia Weikuan , Yan Xingchao , Liu Qiaolian , Zhang Ting , Dong Xishang 
Published: August 2023

AbstractSemantic segmentation plays a vital role in indoor scene analysis. Currently, its accuracy is still limited due to the complex conditions of various indoor scenes. In addition, it is difficult to complete this task solely relying on RGB images. Since depth images can provide additional 3D geometric information to RGB images, researchers chose to incorporate depth images for improving the accuracy of indoor semantic segmentation. However, it is still a challenge to effectively fuse the depth information with the RGB images. To address this issue, a three-stream coordinate attention network is proposed. The presented network reconstructs a multi-modal feature fusion module for RGB-D features, which can realize the aggregation of two modal information along the spatial and channel dimensions. Meanwhile, three convolutional neural network branches are used to construct a parallel three-stream structure, which can, respectively, process the RGB features, depth features and combined features. On one hand, the proposed network can preserve the original RGB and depth feature streams, simultaneously. On the other hand, it can also contribute to utilize and propagate the fusion feature flow better. The embedded ASPP module is used to optimize the semantic information in the proposed network, so as to aggregate the feature information of different scales and obtain more accurate features. Experimental results show that the proposed model can reach a state-of-the-art mIoU accuracy of 50.2% on the NYUDv2 dataset and on the more complex SUN-RGBD dataset.