bluuebunny/crossref_metadata_2025_split huggingface dataset:
Post-PCI Risk Assessment by Inflammation Activity According to Disease Acuity and Time from Procedure
Authors: Song Haegeun , Ahn Jong-Hwa , Kang Min Gyu , Kim Kye-Hwan , Bae Jae Seok , Cho Sang Young , Koh Jin-Sin , Park Yongwhi , Hwang Seok-Jae , Cho Eun Jeong , Byeon Kyeongmin , Kim Sang-Wook , Tantry Udaya S. , Gurbel Paul A. , Hwang Jin-Yong , Jeong Young-Hoon 
Published: January 2023

Background High-sensitivity C-reactive protein (hs-CRP) has been proposed as an indicator of inflammation and cardiovascular risk. However, little is known of the comparative temporal profile of hs-CRP and its relation to outcomes according to the disease acuity.
Methods We enrolled 4,263 East Asian patients who underwent percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) and stable disease. hs-CRP was measured at baseline and 1 month post-PCI. Major adverse cardiovascular events (MACE: the composite occurrence of death, myocardial infarction, or stroke) and major bleeding were followed up to 4 years.
Result The AMI group (n = 2,376; 55.7%) had higher hs-CRPbaseline than the non-AMI group (n = 1,887; 44.3%) (median: 1.5 vs. 1.0 mg/L; p < 0.001), which remained higher at 1 month post-PCI (median: 1.0 vs. 0.9 mg/L; p = 0.001). During 1 month, a high inflammatory-risk phenotype (upper tertile: hs-CRPbaseline ≥ 2.4 mg/L) was associated with a greater MACE in the AMI group (adjusted hazard ratio [HRadj]: 7.66; 95% confidence interval [CI]: 2.29–25.59; p < 0.001), but not in the non-AMI group (HRadj: 0.74; 95% CI: 0.12–4.40; p = 0.736). Between 1 month and 4 years, a high inflammatory-risk phenotype (upper tertile: hs-CRP1 month ≥ 1.6 mg/L) was associated with greater MACE compared to the other phenotype in both the AMI (HRadj: 2.40; 95% CI: 1.73–3.45; p < 0.001) and non-AMI groups (HRadj: 2.67; 95% CI: 1.80–3.94; p < 0.001).
Conclusion AMI patients have greater inflammation during the early and late phases than non-AMI patients. Risk phenotype of hs-CRPbaseline correlates with 1-month outcomes only in AMI patients. However, the prognostic implications of this risk phenotype appears similar during the late phase, irrespective of the disease acuity.
A Novel Ring-Opening/Ring-Closing Cascade Reaction Selectively Induced by Aliphatic Primary Amine Using Phenolic Hydroxyl as a Traceless Directing Group
Authors: Liu Teng , Huang Chao , Huang Shuntao , Li Jingpeng , Yang Qi , Zhan Shuyan 
Published: January 2023

AbstractAn interesting ring-closing/ring-opening cascade reaction selectively induced by aliphatic primary amine for the synthesis of functionalized aminomaleimides is described. This work features phenolic hydroxyl as a traceless directing group that forms a critical six-membered intermediate and then a lactone ammonolysis/intramolecular amidation sequence. This two-step, one-pot practical protocol has broad substrate scope (39 examples) and delivers structurally diverse aminomaleimides in good to excellent yields.
A ‘leftist premium’ to protest movements?: How incumbent partisanship conditions austerity-spurred mass protest
Authors: Suzuki Junpei 
Published: January 2023

AbstractFiscal austerity is a policy characteristic of governments that adhere to conservative economic ideologies. In recent decades, however, especially after the 2009 Eurozone Crisis, leftist and left-centre coalition governments have also adopted austerity policies. While it is documented that fiscal austerity incurs electoral costs upon incumbent governments and these costs depend on their partisanship, whether and how the partisanship of the incumbent government affects the pattern of protest movements remains unknown. In this paper, I hypothesized that fiscal austerity by leftist governments, through adding a ‘premium’ to public grievances and demining citizens’ utility of electoral participation, results in a higher likelihood of protest movements than fiscal austerity implemented by right-dominant governments. I supported this hypothesis by analysing panel data for 37 developed countries between 1973 and 2015. Besides, the partisan-pronounced effects on the protest likelihood are observed particularly for non-violent protests such as demonstrations and strikes and for the post-2000 era.
Activity measurements of the radionuclides 18F, 64Cu, 99mTc and 11C for the NRC, Canada, in the ongoing comparisons BIPM.RI(II)-K4 series and KCRV update in the corresponding BIPM.RI(II)-K1 comparison
Authors: Michotte C , Nonis M , Galea R , Moore K , Gamal I El , Silva I Da 
Published: January 2023

Main text
In 2017, comparisons of activity measurements of 18F, 64Cu, 99mTc and 11C using the Transfer Instrument of the International Reference System (SIRTI) took place at the National Research Council of Canada (NRC, Canada). Ampoules containing 18F, 64Cu, 99mTc and 11C solutions were measured in the SIRTI for about three half-lives (10 half-lives for 11C). The NRC standardized the activity in the ampoules by 4π(PC)β−γ anti-coincidence measurements (CIEMAT/NIST liquid scintillation counting for 11C). The comparisons, identifiers BIPM.RI(II)-K4.F-18, BIPM.RI(II)-K4.Cu-64 and BIPM.RI(II)-K4.Tc-99m are linked to the corresponding BIPM.RI(II)-K1.F-18, BIPM.RI(II)-K1.Cu-64 and BIPM.RI(II)-K1.Tc-99m comparisons. The BIPM.RI(II)-K1 18F and 99mTc key comparison reference values have been updated to include the latest BIPM.RI(II)-K4 linked results and degrees of equivalence for those three comparisons have been evaluated.
To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database https://www.bipm.org/kcdb/.
The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Graphene-like wrapped Ni@C catalyst with magnetic recyclability for selective hydrogenation of nitro-aromatics
Authors: Tan Jin , Lan Ling , Wu Yan-ni , Qiu Song-bai 
Published: January 2023

Abstract
The graphene-like wrapped Ni@C catalysts were facilely synthesized by a modified sol–gel method. Nickel nitrate and citric acid (CA) were adopted as the raw materials to form sol–gel mixture. Under the circumstances, the additive CA were employed not only as a complexing agent but also as a carbon source. It is found that the calcination temperature and the mole ratios between Ni and CA are the key factors affecting the physical property and the catalytic performance of catalysts in the conversion of nitroarenes into corresponding anilines. The results show that the Ni@C-500(1:1) catalyst exhibited the best performance in the hydrogenation of o-chloronitrobenzenes (o-CNB) to o-chloroanilines (o-CAN). The yield of o-CAN was achieved at 100% when o-CNB was completely converted at 40.0 °C under 2.0 MPa H2 for 2.0 h. Furthermore, the Ni@C-500(1:1) catalyst could be separated and recovered easily after reaction by an external magnetic field. The investigated results indicate that the Ni@C-500(1:1) catalyst remained higher activity after using twelve times. More importantly, this kind of catalyst is also active for the selective hydrogenation of other nitroarenes into the corresponding anilines. This new synthetic method may pave a way for producing low-cost Ni@C catalysts on a large scale, which is attractive for industrial anilines applications.
Modulational instability of a Yukawa fluid excitation under the Quasi-localized charged approximation (QLCA) framework
Authors: Dalui Sandip , Kumar Prince , Sharma Devendra 
Published: January 2023

Abstract
Collective response of a strongly coupled system departs from that in continuum phase upon transition to the quasi-crystalline phase, or a Wigner lattice. The nonlinearity driven modulational instability, for example, of a quasi-crystalline dusty plasma lattice wave, is predicted to inevitably grow macroscopic envelope structures at the expense of a mesoscopic carrier wave. The modulational instability in the dimensionally extended quasi-crystalline or amorphous phase of a strongly coupled system, uniquely accessed by the quasi-localized charge approximation (QLCA) formulation, is shown to offer conditional stability over the entire range of spectral scales by prescribing a narrower instability regime. In distinction from the excitations of linear one-dimensional chain of strongly coupled dust grains, the longitudinal modes of a quasi-crystalline phase incorporated by means of a pair correlation function in the present QLCA based treatment shows the lattice excitations to be stable for arbitrarily long wavelengths beyond a finite value of screening parameter κ = a/λ
D = 0.182 at low enough temperature, where a is the inter dust separation and λ
D is the plasma Debye length. However, this unstable domain of the parameter space does grow with increase in the dust temperature which invokes the weak coupling-like effect. The present results show that in comparison to the one-dimensional chains, the dimensionally extended strongly coupled lattice are potentially stable with respect to the macroscopic amplitude modulations. Results offer a greater handle over the macroscopic structures growing from the mesoscopic fluctuations, a mechanism which underlies a variety of processes, ranging from the barrier formation in strongly coupled turbulence to the highly localized modification, induced by collective excitation, of the ultracold ions trapped in strong electromagnetic fields. The existence of the growth rate of instability as well as the maximum modulational growth rate of instability has been investigated for a wide range of values of the screening parameter.
Semiclassical trajectories in the double-slit experiment
Authors: Hernandez Hernandez Hector H , Javier Valdez Carlos R 
Published: January 2023

Abstract
We provide a semiclassical description of the double-slit experiment given by the momentous quantum mechanics. This formulation allows the study of quantum systems by an effective augmented Hamiltonian. The use of canonical variables enables us to comprise all the quantum information into a finite system of equations. We show the evolution of individual particles and their semiclassical trajectories, and how their collective behavior seems to reproduce the well-known quantum interference pattern. We are able to follow the individual evolution of each particle and its interaction with the effective quantum potential, showing that, contrary to the non-crossing rule present in Bohmian mechanics, particle trajectories actually cross each other in our description. By discussing the quantum-effective potential obtained, we mention possible extensions and applications to other areas.
Effect of trapping in coupled kinetic Alfven-acoustic waves in a partially degenerate plasma with quantizing magnetic field
Authors: Asam M T , Bukhari S A , Shah H A , Iqbal Zeeshan , Masood W , Kahlon L Z 
Published: January 2023

Abstract
Inclusion of a quantizing magnetic field in a partially degenerate plasma has interesting effects on the propagation of solitary and nonlinear periodic structures in coupled kinetic Alfven acoustic waves. In this paper, we use two-potential theory to investigate the nonlinear structures using Sagdeev potential approach and further analyze it using nonlinear dynamical methods. It is shown that the existence of solitary structure is sensitive to small temperature effects and quantizing magnetic field in a dense plasma with adiabatically trapped electrons. The work presented here is useful in understanding the low frequency wave propagation in a dense astrophysical environment like white dwarf stars and in low beta laboratory plasmas e.g. intense laser-plasma interactions.
Signal model and event reconstruction for the radio detection of inclined air showers
Authors: Schlüter F. , Huege T. 
Published: January 2023

Abstract
The detection of inclined air showers (zenith angles θ ≳ 65°) with kilometer-spaced radio-antenna arrays allows measuring cosmic rays at ultra-high energies (E ≲ 1020 eV). Radio and particle detector arrays provide independent measurements of the electromagnetic and muonic shower components of inclined air showers, respectively. Combined, these measurements have a large sensitivity to discriminate between air showers initiated by lighter and heavier cosmic rays.

We have developed a precise model of the two-dimensional, highly complex and asymmetric lateral radio-signal distributions of inclined air shower at ground — the “radio-emission footprints”. Our model explicitly describes the dominant geomagnetic emission with a rotationally symmetric lateral distribution function, on top of which additional effects disturb the symmetry. The asymmetries are associated with the interference between the geomagnetic and sub-dominant charge-excess emission as well as with geometrical projection effects, so-called “early-late” effects. Our fully analytic model describes the entire footprint with only two observables: the geometrical distance between the shower impact point at the ground and the shower maximum d
max, and the geomagnetic radiation energy E
geo. We demonstrate that with this model, the electromagnetic shower energy can be reconstructed by kilometer-spaced antenna arrays with an intrinsic resolution of 5% and a negligible bias.
Network controllability measures of subnetworks: implications for neurosciences
Authors: Stocker Julia Elina , Nozari Erfan , van Vugt Marieke , Jansen Andreas , Jamalabadi Hamidreza 
Published: January 2023

Abstract

Objective: Recent progress in network sciences has made it possible to apply key findings from control theory to the study of networks. Referred to as network control theory, this framework describes how the interactions between interconnected system elements and external energy sources, potentially constrained by different optimality criteria, result in complex network behavior. A typical example is the quantification of the functional role certain brain regions or symptoms play in shaping the temporal dynamics of brain activity or the clinical course of a disease, a property that is quantified in terms of the so-called controllability metrics. Critically though, contrary to the engineering context in which control theory was originally developed, a mathematical understanding of the network nodes and connections in neurosciences cannot be assumed. For instance, in the case of psychological systems such as those studied to understand psychiatric disorders, a potentially large set of related variables are unknown. As such, while the measures offered by network control theory would be mathematically correct, in that they can be calculated with high precision, they could have little translational values with respect to their putative role suggested by controllability metrics. It is therefore critical to understand if and how the controllability metrics estimated over subnetworks would deviate, if access to the complete set of variables, as is common in neurosciences, cannot be taken for granted. Approach: In this paper, we use a host of simulations based on synthetic as well as structural magnetic resonance imaging (MRI) data to study the potential deviation of controllability metrics in sub- compared to the full networks. Specifically, we estimate average- and modal-controllability, two of the most widely used controllability measures in neurosciences, in a large number of settings where we systematically vary network type, network size, and edge density. Main results: We find out, across all network types we test, that average and modal controllability are systematically, over- or underestimated depending on the number of nodes in the sub- and full network and the edge density. Significance: Finally, we provide formal theoretical proof that our observations generalize to any network type and discuss the ramifications of this systematic bias and potential solutions to alleviate the problem.
Breath VOC analysis and machine learning approaches for disease screening: a review
Authors: P Haripriya , Rangarajan Madhavan , Pandya Hardik J 
Published: January 2023

Abstract
Early disease detection is often correlated with a reduction in mortality rate and improved prognosis. Currently, techniques like biopsy and imaging that are used to screen chronic diseases are invasive, costly or inaccessible to a large population. Thus, a non-invasive disease screening technology is the need of the hour. Existing non-invasive methods like gas chromatography-mass spectrometry, selected-ion flow-tube mass spectrometry, and proton transfer reaction-mass-spectrometry are expensive. These techniques necessitate experienced operators, making them unsuitable for a large population. Various non-invasive sources are available for disease detection, of which exhaled breath is preferred as it contains different volatile organic compounds (VOCs) that reflect the biochemical reactions in the human body. Disease screening by exhaled breath VOC analysis can revolutionize the healthcare industry. This review focuses on exhaled breath VOC biomarkers for screening various diseases with a particular emphasis on liver diseases and head and neck cancer as examples of diseases related to metabolic disorders and diseases unrelated to metabolic disorders, respectively. Single sensor and sensor array-based (Electronic Nose) approaches for exhaled breath VOC detection are briefly described, along with the machine learning techniques used for pattern recognition.
Hybrid volatilomics in cancer diagnosis by HS-GC-FID fingerprinting
Authors: da Costa Bruno Ruiz Brandão , da Silva Ricardo Roberto , Bigão Vítor Luiz Caleffo Piva , Peria Fernanda Maris , De Martinis Bruno Spinosa 
Published: January 2023

Abstract
Assessing volatile organic compounds (VOCs) as cancer signatures is one of the most promising techniques toward developing non-invasive, simple, and affordable diagnosis. Here, we have evaluated the feasibility of employing static headspace extraction (HS) followed by gas chromatography with flame ionization detector (GC-FID) as a screening tool to discriminate between cancer patients (head and neck—HNC, n = 15; and gastrointestinal cancer—GIC, n = 19) and healthy controls (n = 37) on the basis of a non-target (fingerprinting) analysis of oral fluid and urine. We evaluated the discrimination considering a single bodily fluid and adopting the hybrid approach, in which the oral fluid and urinary VOCs profiles were combined through data fusion. We used supervised orthogonal partial least squares discriminant analysis for classification, and we assessed the prediction power of the models by analyzing the values of goodness of prediction (Q2Y), area under the curve (AUC), sensitivity, and specificity. The individual models HNC urine, HNC oral fluid, and GIC oral fluid successfully discriminated between healthy controls and positive samples (Q2Y = 0.560, 0.525, and 0.559; AUC = 0.814, 0.850, and 0.926; sensitivity = 84.8, 70.2, and 78.6%; and specificity = 82.3; 81.5; 87.5%, respectively), whereas GIC urine was not adequate (Q2Y = 0.292, AUC = 0.694, sensitivity = 66.1%, and specificity = 77.0%). Compared to the respective individual models, Q2Y for the hybrid models increased (0.623 for hybrid HNC and 0.562 for hybrid GIC). However, sensitivity was higher for HNC urine and GIC oral fluid than for hybrid HNC (75.6%) and hybrid GIC (69.8%), respectively. These results suggested that HS-GC-FID fingerprinting is suitable and holds great potential for cancer screening. Additionally, the hybrid approach tends to increase the predictive power if the individual models present suitable quality parameter values. Otherwise, it is more advantageous to use a single body fluid for analysis.
Patient and Clinician Reported Outcomes of the Inframammary Incision “Short Scar Technique” in Primary Breast Augmentation
Authors: Montemurro Paolo , Cheema Mubashir , Pellegatta Tommaso , Hedén Per 
Published: January 2023

Abstract

Background
Breast augmentation is a common aesthetic surgery procedure and surgeons are constantly trying to develop techniques that help improve patients' outcome. One of the most important aspects is achieving a favorable scar. The “traditional” breast augmentation scar is in the inframammary fold (IMF), whereas trans-axillary and trans-umbilical approaches have been described as an attempt to move the “location” of the scar and make it less noticeable. Nonetheless, relatively little attention has been paid to improving the IMF scar, which remains the most commonly used scar for silicone implants.

Objectives
The authors have previously described a technique that uses an insertion sleeve and custom-made retractors to allow implant insertion through a shorter IMF scar. However, at the time, the authors did not evaluate the quality of the scar and patient satisfaction. In this manuscript, the authors describe patient and clinician-reported outcomes for this short scar technique.

Methods
All consecutive female patients, undergoing primary aesthetic breast augmentation with symmetric implants were included in this review.

Results
Three different scar-assessment scales demonstrated good results at 1-year postop, as well as the good correlation between patient-reported and clinician-observed scores. BREAST-Q subscale for overall satisfaction also demonstrated good overall patient satisfaction.

Conclusions
Besides providing an added aesthetic value to the result of breast augmentation, a shorter scar may also appeal to patients who are concerned about the size and quality of postoperative scars and like to search for “before and after” pictures prior to scheduling consultations.

Level of Evidence: 4
Perioperative Low-Dose Prednisolone Treatment Has Beneficial Effects on Postoperative Recovery and Anastomotic Healing in a Murine Colitis Model
Authors: Weber Marie-Christin , Bauer Jannick , Buck Annalisa , Clees Zoé , Oertel Reinhard , Kasajima Atsuko , Reischl Stefan , Wilhelm Dirk , Friess Helmut , Neumann Philipp-Alexander 
Published: January 2023

Abstract

Background and Aims
High-dose glucocorticoid treatment has been identified as a risk factor for anastomotic leakage in patients with inflammatory bowel disease [IBD] undergoing bowel resection surgery. By contrast, active disease during surgery is also associated with elevated morbidity. Perioperative low-dose treatment might be beneficial regarding postoperative outcomes by controlling disease activity. The present study is the first to investigate the dose-dependent effect of perioperative prednisolone therapy in a murine IBD model combining dextran sodium sulphate [DSS] colitis with intestinal anastomosis surgery.

Methods
In 84 10-week-old wild-type mice, a colorectal anastomosis was performed using a microsurgical technique. Half the animals received induction of chemical colitis with 2% DSS via drinking water prior to surgery. In both groups, one-third of the animals received daily oral administration of high-dose [0.533 mg/kg] and one-third low-dose [0.133 mg/kg] prednisolone. Evaluation was performed on postoperative days 3 and 7.

Results
While high-dose prednisolone treatment led to an increased anastomotic leakage rate in mice under colitis, low-dose prednisolone treatment limited preoperative disease activity and did not influence the leakage rate. Histological examination showed a beneficial effect of low-dose prednisolone treatment on microscopic abscess formation at the anastomotic site in DSS mice as well as an increased anastomotic healing score.

Conclusions
We demonstrate a beneficial effect of perioperative short-term low-dose prednisolone treatment on intestinal anastomotic healing in the context of colitis. Perioperative use of short-term low-dose prednisolone treatment might be beneficial in IBD patients who need to undergo surgery during active disease.