bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between time to treatment and outcome in branch vein occlusion
Authors: Kitano Marie , Aoki Shuichiro , Kitamoto Kohdai , Ueda Kohei , Azuma Keiko , Fujino Ryosuke , Inoue Tatsuya , Obata Ryo 
Published: August 2023

Abstract
Purpose
To investigate the association between the time from onset to initial treatment and changes in visual acuity or the number of treatments in patients with branch retinal vein occlusion.
Methods
Thirty-nine eyes of 39 consecutive patients with untreated acute-phase BVO. The patients were initially treated with anti-vascular endothelial growth factor (VEGF) therapy and additional pro re nata therapy within six months of onset. The patients were classified according to the time from disease onset to the first treatment (group A: 28 days or less, group B: over 28 days).
Results
The mean age was 73 ± 8 years (53 to 88). The mean the first treatment time was 31.6 ± 17.9 days. The mean logMAR visual acuity at first treatment was 0.37 ± 0.30. The mean number of treatments was 3.1 ± 1.7. No significant association was observed between the time from onset to the first treatment and changes in the logMAR visual acuity. Patients in group A and central macular thickness at the initial visit were independently associated with the number of treatments at one year (p = 0.03 and p = 0.01, respectively).
Conclusions
At one year, the time between onset to the start of anti-VEGF therapy for BVO was not associated with subsequent visual acuity changes.
High solubility of cellulose in slow-cooling alkaline systems and interacting modes of alkali and urea at the molecular level
Authors: Ai Shuo , Huang Zhenhua , Yu Wanguo , Huang Chengdu 
Published: August 2023

Abstract
The dissolution of microcrystalline cellulose (MCC) in a urea-NaOH system is beneficial for its mechanical processing, but the solubility has been low. The MCC solubility was greatly improved to 14 wt% under a slow-cooling condition with a cooling rate of − 0.3°C/min. The cooling curve or thermal history played a crucial role in the dissolution process. An exotherm (31.9 ± 1.6 J/g MCC) was detected by DSC only under the slow-cooling condition, and the cryogenic dissolution of MCC is attributed to the exothermic interaction between MCC and solvent. More importantly, the low cooling rate promoted the dissolution of MCC by providing enough time for the diffusion of OH− and urea into MCC granules at higher temperatures. The Raman spectral data showed that the intramolecularly and intermolecularly hydrogen bonds in cellulose were cleavaged by NaOH and urea, respectively. XPS and solid-state 13C NMR results showed that hydrogen bonds were generated after dissolution, and a dual-hydrogen-bond binding mode between urea and cellulose was confirmed by DFT calculations. The increase of entropy dominated the spontaneity of cryogenic dissolution of MCC, and the decrease of enthalpy played a minor role. The high solubility of MCC in the slow-cooling process and the dissolution mechanism are beneficial for the studies on cellulose modification and mechanical processing.
Addictive Behavior and Mental Health of Adolescents in Bangladesh: Evidence from Global School-Based Health Survey
Authors: Hossain Sorif , Chowdhury Promit Barua , Mohsin Md. , Biswas Raaj Kishore 
Published: August 2023

Abstract
Aim
This study aims to evaluate the factors associated with addictive behaviour and the mental health of adolescents aged 11–17.
Subject and Methods:
Bivariate analysis and weight-adjusted logistic regression were fitted to a sample size of 2989 adolescents in Bangladesh.
Results
One in ten and one in four adolescents had different substance addictions and some forms of mental health condition, respectively. Sex of participants, being bullied, use of tobacco among parents, parental understanding of their adolescent’s problems, and food affordability were significantly associated with addictive behaviours of adolescents. Bullied males with non-empathetic parents were found to be more vulnerable to addictive behaviors and bullied females showed higher tendencies to mental health issues.
Conclusion
Identifying the vulnerable cohorts and designing interventional policies alongside collaborative efforts can pave the way to sound health and well-being for youths in Bangladesh.
Effect of Triquetrum Bone Excision in Total Wrist Arthrodesis
Authors: Yamak Kamil , Tapan Mehmet 
Published: August 2023

Abstract
Background
Ulnar impaction syndrome is one of the established causes of persistent postoperative discomfort and dissatisfaction following well-performed wrist arthrodesis. This syndrome however remains understudied, and it is unclear how often it occurs in patients. Moreover, while previous studies have led to several recommendations for the treatment of ulnocarpal impaction following arthrodesis surgery, many treatment options currently available may cause the pain in the wrist to be replaced by another type of pain. The aim of this study was to examine the results of excision of the triquetrum and its use as a graft during arthrodesis in patients who underwent total wrist arthrodesis due to end-stage wrist arthrosis and had ulnocarpal impaction causing limitation of pronation/supination of the forearm.
Methods
Three patients who underwent triquetrum excision were included in this study. Potential complications following surgical treatment and union status were evaluated, and Quick-DASH scores were assessed pre- and postoperatively.
Results
The patients were followed up for an average of 18 months. Before surgical treatment, the average motion for forearm supination in patients was 35 (30–40) degrees and the range for pronation was 45 (35–45) degrees. The mean Quick-DASH score before surgical treatment was 69.7 (63.6–75) degrees. In the controls, at the end of the follow-up period, the mean range of motion for forearm supination was 81.6 (80–85) degrees and the mean range for pronation was 85 (80–90) degrees. The mean QuickDASH score was 5.3 (2,3–9.1). No major complication was observed.
Conclusions
Based on our findings, we recommend that in cases with positive ulnar variance, no arthrosis in the distal radioulnar joint, painful and preoperative or intraoperative limited pronation/supination, triquetrum excision be routinely performed with total wrist arthrodesis.
Deacetylase SIRT3 alleviates neuropathic pain by improving mitochondrial fission and fusion in spinal dorsal horn neurons
Authors: Sun Yanyan , Yang Qingqing , Xie Liu , Xu Yiran , Ren Xiuhua , Xu Yuanzhi , Zhang Jingjing , Zhao Sen , Zhang Yidan , Niu Jianbin , Si Tianen , Zang Weidong , Cao Jing 
Published: August 2023

Abstract

Background:The mitochondria contribute to neuropathic pain (NP) by regulating mitochondrial function and cellular redox capacity. Sirtuin3 (SIRT3), an NAD+-dependent deacetylase primarily expressed in the mitochondria, is involved in the regulation of mitochondrial proteins. This study aimed to investigate the effect of SIRT3 within succinate dehydrogenase (SDH) on mitochondrial function and NP in mice with chronic constriction injury (CCI).Methods:Wild-type littermates underwent CCI surgery at 8-10 weeks postnatally. Western-blot and immunofluorescence was applied to detect the changes of SIRT3 protein in SDH after CCI. Lentivirus-SIRT3 and SIRT3-knockout mice (SIRT3-/-) were used to overexpress or knockdown of SIRT3. Mitochondrial fluorescence probe and electron microscope were used to observe the changes of mitochondrial morphology. ROS fluorescent probe dihydroethidium (DHE) and antioxidant enzyme kit were employed to determine the level of oxidative stress in SDH.Results:SIRT3 protein levels were significantly decreased in CCI mice. Overexpression of spinal SIRT3 by intrathecal injection of LV-SIRT3 attenuates pain hypersensitivity in CCI mice. Transgenic SIRT3-knockout mice (SIRT3-/-) show pain allergy in the physiological state. SIRT3 plays a major role in the regulation of mitochondrial fusion protein expression in optic atrophy 1 (OPA1). Ultrastructural analysis showed that CCI and SIRT3-/- mice induced mitochondria with smaller perimeters, areas, and interconnectivity in the SDH. CCI and SIRT3 deletion significantly increased oxidative stress, as evidenced by increased ROS levels and decreased activity of antioxidant enzymes superoxide dismutase (SOD) and catalase (CAT) in the SDH.Conclusion:Taken together, these results suggest that SIRT3 attenuates pain hypersensitivity in mice by regulating dynamic changes and oxidative stress in mitochondria.
The perceptions of frail older adults on contributing factors causing the onset of crises leading to hospital admissions; a qualitative study
Authors: Hoitinga Gercora , Kolk Daisy , MacNeil-Vroomen Janet , Rijkenberg Saskia , Melkert Karianne , Buurman Bianca M. 
Published: August 2023

AbstractBackground Frail older adults living alone are frequently admitted to the emergency department (ED) with a chronic disease exacerbation and are at high risk for adverse outcomes like morbidity and mortality. The aim of this study was to explore the perceptions of frail patients who lived alone, on possible contributing factors causing a health crisis as perceived in the approximately nine months leading up to an ED-visit, and to create a combined patient journey map. Method An exploratory-descriptive qualitative study was conducted, using purposive sampling to recruit frail older patients of an urban academic ED. Semi-structured interviews were performed and analysed by thematic analysis. Patient journey mapping was used to identify, combine, and depict chronological similarities. Results Fifteen interviews contained five themes: ‘continuity of healthcare’, ‘self-perception on frailty’, ‘self-management’, ‘impact of support system within an urban environment’, and ‘acute event prior to ED-visit’. The patient journey map identified uncoordinated care by healthcare providers, deterioration from at least six months before the ED-visit, and an unexpected event that leads to an acute health problem four weeks prior to the ED-visit. Conclusion While patients were aware of the health event leading to the acute hospitalization, they were less aware of the impact of contributing cascading events in the months before. The journey map suggest strategies can be applied to inform older adults, be more patient-oriented, and provide an anticipated plan towards advance care, healthy ageing, and admission avoidance.
Rice husk charcoal and acid modified rice husk charcoal for efficient adsorption of methyl orange
Authors: Zaman Samina , Fatema Mst. Kaniz , Sen Sujoy , Zaman Rafiuz , Chakraborty Tapos Kumar , Tasnime Nishat , Islam Monirul , Haque Sangina , Habib Ahsan , Ghosh Gopal Chandra 
Published: August 2023

Abstract
In this study, methyl orange (MO) was removed from solution using rice husk charcoal (RHC) and acid modified rice husk charcoal (AMRHC). In batch adsorption mode, contact time (1–240 min), pH (3–10), adsorbent dose (1–30 g/L), and initial MO concentration (10–100 mg/L) were investigated. Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) were used to characterize the adsorbent's surface morphology and chemistry. At equilibrium, the highest removal of MO by RHC and AMRHC were 89 and 99%, respectively. Removal efficiency increased with increasing adsorbent dose, while the opposite was observed for adsorption capacity because of the availability of unsaturated adsorption sites. RHC and AMRHC were best described by the Freundlich and Langmuir isotherm models, with maximum adsorption capacities of 4.57 and 11.53 mg/g, respectively. The pseudo-second-order kinetic model fitted well for both adsorption and chemisorption, and the process was controlled by multi-step diffusion. Thermodynamic measurements proved that dye adsorption is a spontaneous endothermic process.
Transcriptome analysis and identification of leaf, tuberous root and fibrous root tissue-specific high temperature stress-responsive genes in sweet potato
Authors: Senthilkumar K M , Raju Saravanan , Velumani Ravi , Gutam Sridhar 
Published: August 2023

Sweet Potato is an important food crop, and its production is affected by environmental stresses, including high temperature. The gene expression patterns and molecular responses in different tissues of sweet potato under high temperature stress were studied using microarray data sets. Analysis revealed that modulation in the expression of key genes and pathways associated with various proteins including enzymes under high temperature stress in leaf, fibrous root and storage root tissues. Tissue-specific responses, with both common and unique cellular responses were observed among the tissues. Pathway analysis revealed the differential regulation of genes involved in DNA replication, metabolism, transport, signaling, and stress response during high temperature stress. Six genes viz., DnaJ-domain protein (IpDnaJ), nuclear protein (IpELF5), heat shock protein 90.1 (IpHsp90.1), ABC transporter (IpABC) hydrolase (IpNUDX1) and alternative oxidase 1a (IpAO1a), were up-regulated in the leaf, fibrous root and tuberous root tissues. These six genes might play an important role in imparting high temperature stress tolerance in the leaf, fibrous root and tuberous root tissues of sweet potato. The information generated provides valuable insights on leaf, tuberous root and fibrous root tissue-specific high temperature stress-responsive genes in sweet potato. These datasets will be helpful in selecting candidate genes and pathways for further functional and genomic analyses, facilitating the genetic improvement of sweet potato with enhanced stress tolerance.
Bill deformities in Egyptian vulture (Neophron percnopterus percnopterus): a noteworthy record from Rajasthan, India
Authors: Punjabi Hira , Samson Arockianathan 
Published: August 2023

AbstractBeak deformities may be permanent or temporary and are caused by various factors. Despite its vast geographical area in India, there has been little research on beak deformities in wild birds, and few cases have been reported. In the present study, we described, as far as we know, the first known report of a beak deformity in the Egyptian vulture (Neophron percnopterus percnopterus) worldwide. On 6 January 2014, the first author (HP) recorded the Egyptian vulture with a heavily deformed bill on the garbage dump in Jorbeed, Bikaner, Rajasthan, India. The causes of the bill abnormality in this individual are unknown, but our record increases the knowledge of the presence of development deformities in Egyptian vultures. We highlight the importance of photographs as a valuable tool for documenting bird beak deformities. In conclusion, we encourage other researchers to report the records of beak deformities, which is necessary for a better understanding of this phenomenon and its insights into the ecological and physiological implications of this condition considerably affecting bird survival.
KAJIAN SEMIOTIKA CERITA RAKYAT SUKU DAYAK SUAID
Authors: Olang Yusuf , Oktaviani Ursula Dwi , Diva Bernadeta 
Published: August 2023

Penelitian ini bertujuan untuk: (1) mendeskripsikan Ikon dalam cerita rakyat suku Dayak Suaid; (2) mendeskripsikan Indeks dalam cerita rakyat suku Dayak Suaid; dan (3) mendeskripsikan Simbol dalam cerita rakyat suku Dayak Suaid. Penelitian ini menggunakan pendekatan kualitatif, dengan motode deskriptif analitik. Data dalam penelitian ini berupa rekaman cerita rakyat suku Dayak Suaid yang berjumlah 5 rekaman cerita yang berbeda dan bersumber dari informan yang berbeda. Data berupa rekaman ditranskripsi menggunakan aplikasi Elan versi 4.9.4, kemudian ditranslasi ke dalam Bahasa Indonesia. Berdasarkan analisis data dari 5 cerita tersebut, ditemukan 53 data temuan yang mencakup 10 Ikon, 23 Indeks, dan 20 Simbol. Hasil penelitian ini dapat disimpulkan bahwa temuan Ikon dalam cerita rakyat suku Dayak Suaid jauh lebih sedikit dibandingkan jumlah temuan Indeks dan Simbol. Hal ini menunjukan bahwa Ikon dalam setiap cerita sangat minim ditemukan. Berdasarkan penelitian yang telah dilakukan, disarankan untuk para peneliti selanjutnya dapat melakukan penelitian yang serupa sebagai tambahan penelitian semiotika yang lebih luas.
PENGUATAN PENDIDIKAN MORAL BAGI ANAK MELALUI DIDIKAN SUBUH DI TAMAN PENDIDIKAN AL-QUR’AN
Authors: Arifin Zuhairansyah , Afrida Afrida , Mukhtar AH Nurkamelia , Sudirman Nurhayati 
Published: August 2023

<p>Dewasa ini nilai-nilai moral dalam masyarakat semakin terbuka menyebabkan perubahan dalam perilaku anak. Tanpa sadar, anak terpapar informasi yang belum tentu baik dan bermanfaat. Kekerasan, ucapan kasar, dan <em>bullying</em> yang ditonton di TV, dilihat, dan dialami, dapat memberi pesan negatif pada anak, pada <em>ending</em>nya berdampak buruk dalam penerapan moralitas sosial dalam masyarakat. Kaum <em>liberal </em>mengatakan, standar moral dapat direvisi atau sepenuhnya dapat berubah segaris dengan kehendak manusia. Sesuatu yang dianggap baik oleh suatu sistem <em>feodalistik</em>, mungkin tidak dapat diterima oleh suatu bentuk kehidupan yang berbeda, oleh karenanya standarisasi moral akan berubah sesuai dengan kondisi zaman. Jika kaum <em>konservatif</em> mempertahankan bahwa standar-standar moral yang mendasar tak dapat berubah, maka aliran <em>kontemporer </em>mengatakan bahwa standar moral bisa berubah secara progresif. Kehidupan sosial-budaya yang bagus, belum tentu baik dalam pandangan orang lain. Ini dikarenakan seperangkat mata dan pengalaman yang berbeda disegenap lapisan masyarakat. Dari sini pula muncul alasan, pentingnya penguatan karakter bagi anak dengan menerapkan pola pengasuhan yang melatih anak untuk mulai mengenal benar dan salah, serta memberi teladan dan membiasakan perilaku baik.</p><p> </p><strong>Kata Kunci</strong>: Pendidikan Moral, Didikan Subuh, al-Qur’an
Multiple Colors Making System Using PLC
Authors: Farhi Lubna , Ali Zain Anwar , Zia Saud 
Published: August 2023

This paper presents an automated multiple color making system. The various stages of work operations included in the adaptation of manually operated color mixing systems towards fully automated multiple colors making system. The proposed system can extract color features of an image and returns the intensities of Red, Green and Blue colors for a specified pixel in the given image. Since RGB Color Model is used for digital communications like televisions and computer monitors, and CMYK Color Model is used for printing and painting. So, for mixing purpose; the intensities of RGB are then converted into the intensities of Cyan, Magenta, Yellow and Black colors which then further converted into the form of electrical signals. Generally, from three primary colors CMY, a wide range of colors will be made with different proportions. The electrical signals will then be transmitted serially to our Logic Controller for mixing process, that sense the level of primary colors to be mixed and then mix colors proportionally in a container accordingly up to a fixed level in order to make different multiple colors of fixed quantity. Simulation results shows that the proposed methodology removes the chances like variation in quantity or inaccuracy which happened with the manually color sensing and mixing. It reduces the labor efforts and makes 7% more accurate with minimum error and achieve good retrieval performance.

Index Terms— Programmable Logic Controller (PLC), Python Image Library (PIL), Color Histogram, RGB / CMYK Color Model, Features Extraction Techniques.
Learning Analytics: A Data Mining and Machine Learning Perspective
Authors: Khan Salam Ullah , Ullah Kifayat , Lodhi Mahvash Arsalan , Bangash Sadaqat Ali Khan 
Published: August 2023

Tremendous proliferation in data generation in the past few years has paved the way for new research and the development of new and improved techniques and algorithms in different fields of science and education. Initially terms like educational data mining emerged as a branch of data mining borrowing techniques from its ancestor. The challenges brought about by this large and heterogeneous data are diverse and needs a greater serious technical treatment. New and emerging fields like learning analytics have been introduced to manage the complexities of this data deluge. Learning analytics deals with data in the context of learner and the learning environment to improve the overall learning experience. The ultimate aim of the field is to make use of the data about learners and their environments to gain insights into the learning process using some of the well-known techniques and algorithms from the fields of data mining and machine learning. The process involves collecting, analysis of data and reporting the results to understand and optimize the learning experience. The fields of data mining and academic analytics closely related to learning analytics. Systematic Literature Review (SLR) is a robust, organized and rigorous literature review and reporting process aimed at identifying, collecting and synthesizing the relevant literature on a research question according to specified criteria. The process is more unbiased and balanced by systematic sequence of steps. This paper presents a systematic literature review by first developing the systematic literature review protocol and then discussing the main findings of the literature review by especially focusing on the applications and uses of machine learning and data mining techniques in the domain of learning analytics.

Index Terms—Systematic Literature Review (SLR), Learning Analytics (LA), Big Data, Educational Data Mining (EDM), Machine Learning (ML).
ANALISIS KEBIJAKAN UNGGAH MANDIRI TUGAS AKHIR MAHASISWA DI UNIVERSITAS SURABAYA
Authors: Masyhur Masyhur , Setiawan Eko 
Published: August 2023

Berdasarkan Peraturan Rektor Universitas Surabaya No. 383 Tahun 2012 tentang Wajib Serah Simpan Karya Ilmiah, Perpustakaan Universitas Surabaya mengembangkan sebuah sistem yang memadukan antara kewajiban serah simpan karya ilmiah dengan layanan self-service seperti yang berkembang di negara-negara maju. Proses unggah karya ilmiah non mandiri yang dilakukan oleh pustakawan dari segi pelaksanaan sampai tahap publikasi memakan waktu yang begitu panjang. Tugas Akhir mahasiswa yang merupakan salah satu karya ilmiah, mendesak untuk segera diterbitkan dengan cara unggah mandiri. Unggah mandiri yang dilakukan mahasiswa tentu lebih banyak manfaatnya jika dibandingkan dengan unggah karya ilmiah yang dilakukan oleh pustakawan. Hal ini terkait dengan kecepatan akses publikasi, mencegah kemiripan judul dan isi, menghemat waktu dan biaya.
Dengan menggunakan metode kualitatif, penelitian ini memaparkan pembahasan, alur kerja, dan gambaran proses kegiatan unggah mandiri lebih rinci dan jelas, dimana sistem yang diterapkan pada unggah mandiri ini terdapat dua antar muka, baik dari sisi mahasiswa maupun antar muka pustakawan. Pada sisi mahasiswa, mereka dapat melakukan unggah mandiri dimanapun yang terhubung dengan internet, sedangkan pada sisi pustakawan akan memeriksa dan memvalidasi hasil unggah mandiri yang telah diunggah oleh mahasiswa.
Begitu banyak manfaat yang didapat dari kegiatan unggah mandiri ini diharapkan dapat terlaksana semakin sempurna dan dapat diterapkan di perpustakaan-perpustakaan lain yang belum menerapkan kebijakan unggah karya ilmiah secara mandiri.