bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metabolic and bariatric surgery in China: A summary of the Greater China Metabolic and Bariatric Surgery Database and comparison with other international registry databases
Authors: Tian Peirong , Fu Jing , Li Mengyi , Liu Yang , Bian Shibo , Zhang Meng , Liu Jia , Jin Lan , Zhang Zhongtao , Zhang Peng 
Published: February 2023

AbstractAimsTo summarize the Greater China Metabolic and Bariatric Surgery Database (GC‐MBD) and to compare patient characteristics and different procedures performed with data from published reports from other international bariatric surgery registries.Materials and MethodsData were extracted from the GC‐MBD registry in 2021. Baseline demographic characteristics, obesity‐related comorbidities and operational information were analysed. Descriptive comparisons of these data were made with the published reports from four other international/national databases, including the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO) registry, the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) database of the United States, the National Bariatric Surgical Registry (NBSR) of the United Kingdom, and the Scandinavian Obesity Surgery Registry (SOReg).ResultsFifty‐three centres in China registered 6807 cases in the GC‐MBD. Compared with published data from the IFSO registry, MBSAQIP, NBSR and SOReg, patients in China undergoing surgery were younger and had a lower body mass index. The incidence of other obesity‐related comorbidities, except for gastroesophageal reflux disease, was also higher than in Western countries. Furthermore, more patients underwent sleeve gastrectomy, less revisional bariatric surgery was reported in China, and jejunojejunal bypass with sleeve gastrectomy, uncommon in other countries, was China's second‐leading bariatric procedure.ConclusionsBy establishing comprehensive national registries such as the GC‐MBD, real‐world information can be gathered on clinical practice and patient outcomes. Insights into variations in clinical practice can be identified by comparing reports from different countries, which can help in making and evaluating healthcare policies on the best clinical practices at a national level.
Neural tracking of visual periodic motion
Authors: Varlet Manuel , Nozaradan Sylvie , Schmidt Richard C. , Keller Peter E. 
Published: February 2023

AbstractPeriodicity is a fundamental property of biological systems, including human movement systems. Periodic movements support displacements of the body in the environment as well as interactions and communication between individuals. Here, we use electroencephalography (EEG) to investigate the neural tracking of visual periodic motion, and more specifically, the relevance of spatiotemporal information contained at and between their turning points. We compared EEG responses to visual sinusoidal oscillations versus nonlinear Rayleigh oscillations, which are both typical of human movements. These oscillations contain the same spatiotemporal information at their turning points but differ between turning points, with Rayleigh oscillations having an earlier peak velocity, shown to increase an individual's capacity to produce accurately synchronized movements. EEG analyses highlighted the relevance of spatiotemporal information between the turning points by showing that the brain precisely tracks subtle differences in velocity profiles, as indicated by earlier EEG responses for Rayleigh oscillations. The results suggest that the brain is particularly responsive to velocity peaks in visual periodic motion, supporting their role in conveying behaviorally relevant timing information at a neurophysiological level. The results also suggest key functions of neural oscillations in the Alpha and Beta frequency bands, particularly in the right hemisphere. Together, these findings provide insights into the neural mechanisms underpinning the processing of visual periodic motion and the critical role of velocity peaks in enabling proficient visuomotor synchronization.
Dual antiplatelet therapy in acute ischaemic stroke with or without cerebral microbleeds
Authors: Wang Meng , Yang Yuyuan , Wang Yajuan , Luan Moxin , Xu Lulu , Zhong Meixiang , Zheng Xueping 
Published: February 2023

AbstractAntiplatelet therapy (APT) plays an important role in the prevention of ischaemic stroke (IS). Our aim was to assess the influence of short‐term single APT (SAPT) and dual APT (DAPT) on the prognosis of patients with acute IS with and without cerebral microbleeds (CMBs). We conducted a single‐centre, retrospective, observational cohort study of patients with acute IS who underwent susceptibility‐weighted imaging (SWI) to determine the presence of CMBs between January 2015 and December 2020. The patients were treated with either DAPT or SAPT and followed up for at least 2 years. The primary endpoint was a composite of recurrent IS and intracerebral haemorrhage (ICH), while either recurrent IS or ICH was considered as other endpoints. We computed weighted Kaplan–Meier curves and identified risk factors using the Cox proportional hazards model. Among the 581 enrolled patients, those with CMBs (n = 225; P = 0.004) had a higher risk of the primary endpoint than those without CMBs (n = 356), especially higher risk of recurrent IS (P = 0.029). In the SAPT group, the presence of CMBs increased the risk of the primary endpoint (P = 0.013), especially that of recurrent IS (P = 0.019). In the DAPT group, the occurrence of ICH was higher in patients with CMBs (P = 0.031). The CMB distribution did not influence the risk of recurrent IS or ICH. In patients with acute IS and CMBs, DAPT may offset the risk of recurrent IS due to CMBs but increase the risk of ICH.
Functional outcome after initial and multiple intracerebral hemorrhages in children with cerebral cavernous malformations
Authors: Santos Alejandro N. , Rauschenbach Laurèl , Gull Hannah Hadice , Dinger Thiemo Florin , Chihi Mehdi , Li Yan , Tippelt Stephan , Dohna‐Schwake Christian , Schmidt Börge , Jabbarli Ramazan , Wrede Karsten H. , Sure Ulrich , Dammann Philipp 
Published: February 2023

AbstractBackground and purposeWe aimed to assess the course and predictors of functional outcome after single and multiple intracerebral hemorrhage (ICH) in pediatric patients with cerebral cavernous malformations (CCMs) and to conduct a risk assessment of a third bleed during the first follow‐up year after second ICH.MethodsWe included patients aged ≤18 years with complete baseline characteristics, a magnetic resonance imaging dataset, ≥1 CCM‐related ICH and ≥1 follow‐up examination, who were treated between 2003 and 2021. Neurological functional status was obtained using modified Rankin Scale scores at diagnosis, before and after each ICH, and at last follow‐up. Kaplan–Meier analysis was performed to determine the cumulative 1‐year risk of third ICH.ResultsA total of 55 pediatric patients (median [interquartile range] age 12 [11] years) were analyzed. Univariate analysis identified brainstem cavernous malformation (BSCM; p = 0.019) as a statistically significant predictor for unfavorable outcome after second ICH. Outcome after second ICH was significantly worse in 12 patients (42.9%; p = 0.030) than after first ICH and in five patients (55.6%; p = 0.038) after a third ICH compared to a second ICH. Cumulative 12‐month risk of rebleeding during the first year after a second ICH was 10.7% (95% confidence interval 2.8%–29.37%).ConclusionsPediatric patients with a BSCM have a higher risk of worse outcome after second ICH. Functional outcome improves over time after an ICH but worsens following each ICH compared to baseline or previous ICH. Second bleed was associated with neurological deterioration compared to initial ICH, and this deteriorated further after a third ICH.
Oesophageal glomus tumours: rare neoplasms with aggressive clinical behaviour
Authors: Birkness‐Gartman Jacqueline E , Wangsiricharoen Sintawat , Lazar Alexander J , Gross John M 
Published: February 2023

AimsGlomus tumours are neoplasms with perivascular smooth muscle differentiation, which rarely occur in the oesophagus and may behave aggressively in this site based upon prior case reports. This study describes the clinicopathologic features of three oesophageal glomus tumours diagnosed at two large academic institutions between 1984 and 2022.Methods and resultsThree cases of oesophageal glomus tumours were identified. Patients included two females and one male, with an age range of 19–65 years. All three tumours behaved in a malignant fashion, with metastases to various sites (lymph nodes, lung, pericardium, pleura, diaphragm, scalp). One patient developed an aorto‐oesophageal fistula, resulting in a fatal haemorrhage. Tumours ranged in size from 4.5 to 8.1 cm. Histologically, all tumours had a multinodular, perivascular growth pattern. The neoplasms showed varying degrees of cytologic atypia and spindling, elevated mitotic activity (2–12 mitotic figures per 10 high‐power fields), and necrosis was seen in in two cases. All tumours expressed smooth muscle actin by immunohistochemistry, and harboured NOTCH gene alterations (MIR143::NOTCH2 fusion in two cases; NOTCH3 rearrangement and NOTCH1 point mutation in one case). An ATRX splicing mutation in exon 10 was also identified in one case.ConclusionOesophageal glomus tumours pose diagnostic challenges, given their rarity at this site, but can be recognised by their characteristic perivascular growth pattern, round central nuclei, and supportive ancillary studies. Given the propensity for aggressive behaviour in this location, we recommend management by a multidisciplinary sarcoma team for optimal outcome.
Efficacy and safety of oral isotretinoin in the treatment of moderate to severe seborrheic dermatitis: a retrospective study
Authors: Yanfei Zhang , Xiaoying Ning , Dingwei Zhang , Wei Wang , Jianwen Ren 
Published: February 2023

AbstractBackground and objectivesSeborrheic dermatitis is a common, chronic, and recurrent inflammatory skin disease. There are few studies on oral isotretinoin in the treatment of seborrheic dermatitis. The aim of this research was to analyze the efficacy and safety of oral isotretinoin in the treatment of patients with moderate to severe seborrheic dermatitis.MethodsThis was a retrospective study. All included patients were diagnosed as moderate to severe seborrheic dermatitis and treated with oral isotretinoin from January 2019 to December 2020. Symptom Scale of Seborrheic Dermatitis (SSSD) was used to evaluate the overall severity status of disease.ResultsA total of 48 patients with moderate to severe seborrheic dermatitis were enrolled, of which 26 patients were treated with oral isotretinoin at a dose of 20 mg/day, and 22 patients were treated with oral isotretinoin at a dose of 10 mg/day. The duration of treatment was 2.42 ± 0.98 months (range: 2–6 months). The absolute SSSD values were 10.63 ± 1.02 for all 48 patients, 10.95 ± 1.15 and 10.30 ± 1.11 for patients with a dose of 20 and 10 mg/day, respectively. At the endpoint, there were no significant difference in SSSD values between the two groups (2.21 ± 0.24 vs. 2.35 ± 0.46, P = 0.18). The patients were satisfied with the two treatment schemes, and the difference was not statistically significant (P = 0.78). The most common side effect was cheilitis; however, no serious adverse events occurred in either group.ConclusionsWhen considering efficacy and safety, oral isotretinoin can be used to treat patients with moderate to severe seborrheic dermatitis.
A meta‐analysis on the characteristics of placebo effects on urinary function in placebo‐controlled clinical trials among Japanese patients
Authors: Hara Tomohiko 
Published: February 2023

AbstractObjectivesThis study aimed to assess the effect sizes, changes over time, and ethnic differences in placebo effects on urinary function among Japanese patients participating in clinical trials.MethodsA meta‐analysis of 30 Japanese placebo‐controlled clinical trials was conducted to determine the placebo effects on three functions: daily urinary frequency, nocturnal urinary frequency, and average urine volume per void.ResultsThe I‐square heterogeneity values for the basic values of the three functions ranged from 84.5% to 97.9%, with differences among trials. Longitudinal analysis (1 to 12 weeks) indicated an enhanced placebo effect for up to 8 weeks and no consistency among trials on nocturnal urinary frequency (p < 0.01), unlike those on daily urinary frequency and average urine volume per void (p = 1.0). Based on the random‐effects model, the mean differences in urinary frequency at 4, 8, and 12 weeks were −0.70 (−0.80; −0.60), −1.06 (−1.16; −0.96), and −1.18 (−1.34; −1.01), respectively. Furthermore, the mean difference (95% confidence interval) in nocturnal urinary frequency and volume of urination per void at 12 weeks was −0.63 (−0.94; −0.31) and 9.67 (7.25; 12.1), respectively.ConclusionsMy findings suggest an increase in the strength of placebo effects over time (up to 8 weeks). A comparison of my results to those published in previous global reports showed no meaningful differences in placebo effects among ethnic groups. The consistent placebo effect size on urinary function could be an external indicator in clinical trials.
Transcutaneous sacral neuromodulation for pelvic pain and non‐relaxing pelvic floor: Findings from a pilot study
Authors: Terzoni Stefano , Mora Cristina , Sighinolfi Maria Chiara , Gaia Giorgia , Pinna Barbara , Rocco Bernardo , Destrebecq Anne 
Published: February 2023

AbstractWe sought to evaluate the effectiveness and acceptability by patients of transcutaneous sacral roots neuromodulation (TSRN) by paravertebral placement of surface electrodes to treat pelvic pain and pelvic muscle stiffness. Pelvic pain is a disabling condition, often related to non‐relaxing pelvic muscles. Causes for the onset are often unclear; noninvasive treatment targeted at maintenance factors can be administered by nurses in some countries. previous studies have investigated the role of invasive stimulation for pelvic pain; TSRN has proved successful in other pelvic disorders. We conducted a pilot study on a sample of consecutive patients of both genders, reporting pelvic pain (chronic or not). Weekly sessions of TSRN with surface electrodes were performed; pain was recorded with the numeric rating scale (NRS) at baseline and after the end of the rehabilitation plan. Therapeutic success was defined as a reduction of 50% in pain scores. Twenty patients were enrolled, most complaining multiple symptoms apart from pain. Seven males had primary prostate pain syndrome, one had history of orthopaedic surgery, and eight had muscle stiffness (Median = 3 out of 4, IQR = [3;3], range [2;4]). Sixteen patients (12 males and 4 females) had chronic pelvic pain. The median NRS values in the sample at baseline was 4[5.5–7.5] with no significant differences between genders (p = 0.144) and decreased significantly (Me = 0.5, IQR[0.0–1.0], p < 0.001) after a median of 20 weekly sessions (range [10–30]). The results indicated clinically relevant benefit for all patients (ω2 = 0.689, 95%IC[0.505–0.793]) Decrease in pelvic muscle stiffness was significant (from Me = 3, IQR [3] to Me = 0, IQR[0–1], p < 0.0001) without differences between the genders (p = 0.711). No significant difference was found in the number of sessions required by males and females to achieve therapeutic success (p = 0.282). TSRN seems a promising treatment for pelvic pain and can be performed in outpatients' clinics with low costs and no invasivity. Further studies on larger, randomized samples are required to confirm these results.
Political uncertainty and investments by private and state‐owned enterprises
Authors: Chaudhry Neeru , Veld Chris 
Published: February 2023

AbstractWe study corporate investments around national elections in India. Investment rates drop by a nonsignificant 2.2% for state‐owned enterprises (SOEs) in election years. The decrease is significantly larger for private firms, which record an investment drop of 7.4%. The decrease in investment for private firms is likely attributable to political uncertainty. SOEs balance political uncertainty with the desire to woo voters who want government investments. Investments in election years are perceived positively for both private firms and for SOEs. Increased investment by SOEs and reduction in investment by private firms during election years are associated with improved investment efficiency.
Promoting empowerment and self‐care in older women through participatory action research: Analysis of the process of change
Authors: Ros‐Sanchez Tania , Lidon‐Cerezuela Maria Beatriz , Lopez‐Benavente Yolanda , Abad‐Corpa Eva 
Published: February 2023

AbstractAimTo generate and understand the process of change in the empowerment of women from 60 to 80 years old through a Participatory Action Research. Specific aim: To analyse the women participants' experiences concerning empowerment and self‐care.DesignWe use the Participatory Action Research approach (in its critical option) in the Socio‐critical Paradigm and applying the Kemmis and McTaggart Model.MethodsA group of 10 women participants from 60 to 80 years old was created and developed the Participatory Action Research from June 2019 to May 2020. This group was involved in 22 group sessions, individual interviews, reflective diaries and triangulation with quantitative data.ResultsFindings were interpreted based on the Gestalt Self Theory. Women generated changes in their empowerment based on three characteristics (self‐determination, self‐esteem and self‐confidence) and, consequently, in their self‐care. They did so according to two distinct patterns of behaviour: Leader women and follower women. The former took the lead in transforming their realities and the latter observed them and evolved in a slower and more reflective manner. These changes had an impact on the most individual level (inner world) and went beyond that barrier, modifying in turn their immediate surroundings and the social level (outer world).ConclusionsThe group of older women began to consider their needs and consider themselves as important once they worked on their self‐determination, self‐esteem and self‐confidence; we show these are key aspects to work on their empowerment and promote their self‐care.ImpactThe patterns of behaviour and dimensions of empowerment detected may help in future research designs and emancipatory community interventions in this population group.
A new species of the hagfish genus Eptatretus (Myxinidae) from the Bahamas, western North Atlantic
Authors: Fernholm Bo , Mincarone Michael Maia 
Published: February 2023

AbstractA new species of the hagfish genus Eptatretus (Myxinidae) is described based on two specimens (407–433 mm total length) collected off the northern Bahamas, between depths of 910 and 1153 m. The new species is distinguished from its congeners by having seven pairs of gill apertures well‐spaced and arranged in a near straight line, a 3/2 multicusp pattern of teeth, 10–11 anterior unicusps, 50–51 total cusps, 12–14 prebranchial pores, 48–52 trunk pores, 79–84 total pores, and no nasal‐sinus papillae. An identification key for the species of Eptatretus from the western Atlantic Ocean is also provided.
Reproductive phenology and behaviour of endangered redside dace (Clinostomus elongatus) in urban streams
Authors: Watt Ashley M. , Drake D. Andrew R. , Lawrie David , Pitcher Trevor E. 
Published: February 2023

AbstractInvestigation of the reproductive phenology and spawning behaviour of imperilled species in relation to environmental variability is needed to understand a critical component of species life history. In this study, we used redside dace (Clinostomus elongatus), a freshwater leuciscid listed as Endangered under Canada's Species at Risk Act, to model spawning phenology and make predictions about spawning initiation using historical and climate change projected thermal cues (measured as cumulative growing degree days), and provide an ethological description of spawning behaviour. Logistic regression models applied to 4 years of average daily stream water temperature data and field behavioural observations of the onset of spawning activity indicated a 50% probability of spawning initiation when cumulative growing degree days reached 214°C days and a 95% probability of spawning initiation at 288°C days. Using two climate change scenarios (i.e., a mid‐century 1.6°C increase and an end of century 3.6°C increase), spawning initiation was predicted to advance 3 days by the year 2050 and 7 days by the year 2100. Underwater video cameras placed at two sites within an urban stream captured 73 unique spawning events revealing that redside dace spawn in pairs as well as in dense, tightly packed groups (more than 20 individuals). Moreover, there is evidence of redside dace having a polygynandrous mating system, as female redside dace spawned with multiple males in 45.2% of the total spawning events recorded. Taken together, this study provides important insights into redside dace spawning initiation and behaviour, key life‐history traits having conservation implications for future reproductive success and, ultimately, population dynamics.
Decision‐making about dialysis: Beyond just dialysis or death
Authors: Liu Christine Kee , Taffel Leah , Russell Matthew , Wong Susan P. Y. , Russell Howard , Vig Elizabeth K. 
Published: February 2023

AbstractNearly half of the persons receiving dialysis in the United States are aged 65 years or older. Kidney failure occurs most frequently in older adults, and typically triggers a discussion regarding dialysis treatment. In this Special Article, we describe the journey of Mr. Howard Russell, an older adult who experienced kidney failure and underwent dialysis. Using the experience of Mr. Russell, we illustrate the complexity of dialysis decision‐making, including how disease trajectory and health policy can potentially impede older adults from achieving “what matters.” Our intent is to provide guidance regarding these barriers and support to clinicians who are sharing similar journeys with older adults making decisions about dialysis. Based on Mr. Russell's journey, we suggest that when discussing dialysis with an older adult, four points be considered: (1) recognize if dialysis is needed long‐term; (2) understand what matters for the older adult; (3) sync the treatment plan when what matters changes; and (4) set up with resources for kidney failure, which is limited but evolving.