bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Lokasi dan Variasi Ketebalan Dinding Geser Kantilever pada Bangunan Bertingkat Simetris
Authors: Grisella Audria Gunawan  , Ade Lisantono  , Yoyong Arfiadi  , Junaedi Utomo  
Published: January 2025

Struktur bangunan beton bertulang bertingkat dapat mengalami momen guling sebagai akibat dari adanya gaya aksial dan lateral. Selain itu, struktur juga menghasilkan gaya geser yang besar seiring dengan peningkatan struktur sehingga rentan terhadap keruntuhan. Keruntuhan struktur tersebut dapat dicegah dengan menggunakan elemen struktur yang dapat memberikan kekakuan dan kekuatan yang cukup, salah satunya yaitu dinding geser. Dinding geser merupakan elemen vertikal yang menahan beban lateral, seperti beban gempa dan beban angin. Dari permasalahan tersebut, maka penelitian ini bertujuan untuk mengetahui pengaruh lokasi dan variasi tebal dinding geser pada bangunan beton bertulang bertingkat. Analisis dilakukan pada bangunan simetris 7 lantai dengan menggunakan analisis Respon Spektrum. Struktur dianalisis dengan bantuan software SeismoStruct. Struktur berada di kota Yogyakarta dengan kondisi tanah sedang. Model struktur akan dibagi menjadi empat tipe sesuai dengan lokasi dan variasi ketebalan dinding gesernya. Dinding geser terletak di sudut terluar dan bagian tengah setiap sisi terluar bangunan. Nilai perpindahan kolom dan gaya elemen, baik kolom maupun balok dari empat model akan dibandingkan. Hasil analisis menunjukkan bahwa ketebalan dinding geser tidak berpengaruh secara signifikan pada perpindahan kolom dan gaya- gaya elemen struktur. Sedangkan lokasi dinding geser berpengaruh secara signifikan terhadap perpindahan kolom dan gaya-gaya elemen strukturnya. Model dengan dinding geser di sudut terluar struktur dan memiliki variasi ketebalan dinding geser merupakan model struktur yang memiliki kekakuan paling baik dibandingkan keempat model lainnya.
PENYELIDIKAN TANAH YANG EFEKTIF UNTUK KAJIAN PONDASI BANGUNAN GEDUNG SEDERHANA DALAM KONTEKS PERIZINAN SLF/PBG
Authors: I Made Kusuma Wiranata  , I Nengah Sinarta  
Published: January 2025

Penyelidikan tanah merupakan tahapan penting dalam proses perencanaan bangunan sipil. Penyelidikan tanah dapat memastikan kestabilan dan keamanan pondasi bangunan, khususnya dalam konteks perizinan SLF/PBG (Sertifikat Laik Fungsi/Persetujuan Bangunan Gedung). Namun, pada bangunan gedung sederhana, terutama yang berada di daerah datar dan lereng, kesadaran akan pentingnya penyelidikan tanah sering kali masih rendah. Penelitian ini bertujuan untuk mengevaluasi metode penyelidikan tanah yang efektif dan sesuai untuk desain pondasi bangunan sederhana guna memenuhi persyaratan perizinan SLF/PBG. Metode yang digunakan dalam penelitian ini meliputi studi literatur dan Focus Group Discussion (FGD) dengan para praktisi teknis yang terlibat dalam pengurusan perizinan bangunan. Fokus penelitian adalah pada penggunaan uji CPT (Cone Penetration Test) dan SPT (Standard Penetration Test) sebagai teknik utama penyelidikan tanah, serta analisis laboratorium tambahan untuk bangunan di daerah lereng. Hasil penelitian menunjukkan bahwa untuk bangunan di daerah datar penyelidikan tanah yang direkomendasikan yaitu kombinasi uji CPT dan SPT, kemudian untuk di daerah tebing atau lereng perlu dilakukan penyelidikan tanah laboratorium untuk memberikan data yang cukup untuk desain pondasi yang aman dan sesuai standar perizinan. Penelitian ini juga mengidentifikasi tantangan utama dalam pelaksanaan penyelidikan tanah, seperti kurangnya sumber daya dan pengetahuan teknis di lapangan. Rekomendasi yang dihasilkan mencakup standar minimal penyelidikan tanah untuk mendukung perizinan bangunan sederahan yang lebih efisien dan efektif di Indonesia.
ANALISIS KEBUTUHAN INFRASTRUKTUR SISTEM PEMANENAN AIR DI SUBAK BALANGAN DESA KUWUM KABUPATEN BADUNG
Authors: I Gusti Agung Putu Eryani  , Made Widya Jayantari  , I Gusti Ngurah Hesa Respati Haditama  
Published: January 2025

Desa Kuwum di Kabupaten Badung, Bali, mempertahankan sistem irigasi tradisional subak, yang memainkan peran penting dalam mendistribusikan air secara adil kepada petani. Namun, tantangan serius seperti perubahan iklim dan konflik penggunaan air mengakibatkan kekurangan pasokan air. Untuk mengatasi masalah ini, pembangunan embung geotekstil sebagai infrastruktur pemanenan air menjadi solusi inovatif. Embung geotekstil, menggunakan material geotekstil, memiliki keunggulan dalam daya tahan, fleksibilitas, dan biaya perawatan yang rendah. Sistem ini mampu menampung air hujan yang melimpah pada musim hujan untuk digunakan saat musim kemarau, serta mengurangi risiko banjir dengan mengalirkan air secara bertahap ke saluran irigasi. Dalam implementasinya, analisis lokasi strategis dan desain yang sesuai dengan kebutuhan lokal sangat penting, melibatkan partisipasi aktif dari komunitas subak. Pembangunan embung ini diharapkan dapat meningkatkan produktivitas pertanian, mengurangi risiko gagal panen, dan mendukung kesejahteraan ekonomi masyarakat Desa Kuwum. Selain manfaat teknis, embung geotekstil juga berkontribusi pada keberlanjutan sistem subak, menjaga keseimbangan ekosistem, dan melestarikan warisan budaya. Dengan demikian, pembangunan embung geotekstil di Subak Balangan merupakan langkah strategis untuk memastikan ketersediaan air yang cukup sepanjang tahun dan meningkatkan kualitas hidup masyarakat, serta menghadapi tantangan perubahan iklim yang semakin mendesak
ANALISIS DEBIT BANJIR RANCANGAN DAERAH ALIRAN SUNGAI YEH HO DENGAN METODE HSS NAKAYASU
Authors: Made Widya Jayantari  , I Gusti Agung Putu Eryan  
Published: January 2025

Sumber daya air adalah elemen esensial bagi kehidupan manusia dan ekosistem yang memerlukan pengelolaan yang bijaksana untuk memastikan keberlanjutan. Pengelolaan Daerah Aliran Sungai (DAS) merupakan komponen kunci dalam strategi pengelolaan sumber daya air, karena berfungsi sebagai penerima, penyimpan, dan penyalur air hujan ke sungai utama. Pengelolaan DAS yang efektif dapat mengurangi risiko bencana seperti banjir dan kekeringan, serta menjaga kualitas air dan tanah. Salah satu parameter penting dalam pengelolaan ini adalah debit rancangan, yang digunakan untuk merancang infrastruktur seperti bendungan dan saluran irigasi. Ketidakakuratan dalam perhitungan debit rancangan dapat mengakibatkan kerugian ekonomi dan sosial yang signifikan.Penelitian ini fokus pada analisis debit rancangan di DAS Yeh Ho di Bali menggunakan metode HSS Nakayasu. DAS Yeh Ho, dengan luas 172,943 km², mengalami masalah banjir dan kekeringan akibat luas lahan kritis yang signifikan. Metode HSS Nakayasu dipilih karena kesederhanaannya dan kemampuannya memberikan estimasi akurat meskipun dengan data terbatas. Penelitian melibatkan pengolahan data curah hujan dari tiga stasiun pengamatan selama sepuluh tahun, analisis frekuensi, dan uji kesesuaian distribusi. Hasil analisis menunjukkan fluktuasi curah hujan maksimum dan memperkirakan debit banjir maksimum untuk berbagai periode ulang, dari 361,490 m³/detik pada periode ulang 2 tahun hingga 650,323 m³/detik pada periode ulang 1000 tahun. Hasil ini menekankan perlunya perencanaan dan pengelolaan DAS yang lebih baik untuk mengurangi dampak banjir dan memastikan keberlanjutan lingkungan serta ekonomi melalui perencanaan infrastruktur yang tepat dan konservasi sumber daya.
IDENTIFIKASI DAN KARAKTERISASI SAWAH TEKNIS DAN NON TEKNIS BERBASIS SIG (SISTEM INFORMASI GEOGRAFIS) DI SUB-DAS BILA
Authors: Rusdianto Rusdianto , Asra Reza , Thamrin Nining Triani , Mubarak Husnul 
Published: January 2025

Hubungan daerah aliran sungai (DAS) dengan lahan sawah, yakni DAS adalah wilayah perairan dangkal yang topografinya didominasi oleh pegunungan, punggung-punggung gunung yang menampung dan menyimpan air hujan sebelum dilepaskan menuju lahan sawah melalui sungai utama. Penelitian ini bertujuan untuk mengidentifikasi sawah teknis dan non teknis berbasis SIG, dan menganalisis karakteristik sawah teknis dan non teknis dari berbagai aspek. Penelitian ini menggunakan metode pendekatan deskriptif kuantitatif berbasis sistem infomasi geografis (GIS). Interpretasi data citra sentinel 2A, kemudian dilakukan digitasi onscreen untuk menghasilkan peta lahan sawah. Kemudian untuk mengidentifikasi sawah teknis dan non teknis, dilakukan digitasi onscreen dengan bantuan wawancara terhadap instansi terkait. Analisis karakteristik dilakukan dengan overlay peta kemiringan lereng, elevasi dan jenis tanah untuk mengidentifikasi karakteristik biofisik lahan, sedangkan karakteristik ekonomi dan pengelolaan dilakukan dengan metode wawancara. Hasi penelitian Luas total lahan sawah pada Sub-Das Bila 5842,35 ha. lahan sawah non teknis memiliki luas 2777,97 ha dan teknis 3064,38 ha. Sawah Non Teknis yang paling mendominasi pada kemiringan datar 0-8% seluas 1637,05 ha (28,02%). Begitu pun sawah teknis dengan kemiringan datar 0-8% seluas 2393,76 ha (40,97%). Sawah non teknis mendominasi pada ketinggian 0-500 dpl (dengan luas 2643,66 ha (45,25%). Begitu pun sawah teknis 0-500 dpl, dengan luas 3061,55 ha (52,4%). sawah non teknis memiliki jenis Tanah dystropepts 527,73 ha 9,03%, 1,09 (ha) 0,02% Eutropepts, 1280,05 (ha) 21,91% Paleudults, 104,36(ha) 1,79% tropaquepts, 272,99 (ha) 4,67% Tropudalfs, 591,73 (ha) 10,1% Tropudults. Teknis dengan luas 1078,16 ha 18,48% Paleudults dan 1986,22 ha 34% Tropaquepts. Penanaman dilakukan 2 kali dalam setahun baik sawah teknis maupun non teknis. Untuk pemberian air pada lahan sawah non teknis hanya mengandalkan air hujan untuk kebutuhan sawah. Sedangkan sawah teknis mengandalkan air dari jaringan irigasi, pipa dan mesin pompa sebagai alat bantu.
FINANCIAL TECHNOLOGY INVESTMENTS AND THEIR IMPACT ON ECONOMIC GROWTH
Authors: MIMOUNI Yassine , BESSOUYAH Mouna 
Published: January 2025

This study aims to measure the impact of financial technology investments on economic growth around the world during the period (2014-2023). The error correction model ECM was used, and the results of the estimates showed that there is no causal relationship between the two variables in the short term; and after testing After valuation of transactions, it turned out that the error correction coefficient CointEq is negative and significant; this explains the existence of a long-term equilibrium relationship between the study variables, and from the test of the analysis of the statement, The shocks that reflect any change in the level of GDP variable by explaining the variance that the occurrence of any single structural shock in financial technology investments by 1% has a positive impact on GDP, and after analyzing the response functions to random shocks, it was found that the degree of response of both variables has been achieved since the first period.
N‐Acetylcysteine‐Derived Carbon Dots for Free Radical Scavenging in Intervertebral Disc Degeneration
Authors: Wu Shang , Shi Yu , Jiang Letao , Bu Wenzhen , Zhang Kai , Lin Wenzheng , Pan Chun , Xu Zhuobin , Du Jianwei , Chen Hao , Wang Huihui 
Published: May 2023

AbstractIntervertebral disc degeneration (IVDD) is associated with oxidative stress induced reactive oxygen species (ROS) dynamic equilibrium disturbance. Nanozymes, as nanomaterials with enzyme‐like activity, can regulate intro‐cellular ROS levels. In this study, a new carbon dots nanozyme, N‐acetylcysteine‐derived carbon dots (NAC‐CDs), is developed and proved to be an ideal antioxidant and anti‐senescent agent in IVDD management. The results confirmed the NAC‐CDs have satisfactory biocompatibility and strong superoxide dismutase (250 U mg−1), catalase, glutathioneperoxidase‐like activity, and total antioxidant capacity. Then, the powerful free radical scavenging and antioxidant ability of NAC‐CDs are demonstrated in vitro as observing the reduced ROS in H2O2 induced senescent nucleus pulposus cells (NPCs), in which the elimination efficiency of toxic ROS is more than 90%. NAC‐CDs also maintained mitochondrial homeostasis and suppressed cellular senescence, subsequently inhibited the expression of inflammatory factors in NPCs. In vivo, evaluations of imaging and tissue morphology assessments suggested that disc height index, magnetic resonance imaging grade and histological score are significantly improved from the degenerative models when NAC‐CDs is applied. In conclusion, the study developed a novel carbon dots nanozyme, which efficiently rescues IVDD from ROS induced NPCs senescence and provides a potential strategy in management of IVDD in clinic.
Efficacy and safety following two or more years of vagus nerve stimulation (VNS Therapy) in pediatric patients with drug‐resistant epilepsy enrolled in a Russian VNS Registry
Authors: Feygina Anna A. , Koshelyaevskaya Yana N. , Dibué Maxine , Voronkova Kira V. , Klochkov Mikhail N. , Koroleva Nadezhda Y. , Ivanov Stanislav S. , Bolshakova Ekaterina S. , Fatykhova Elza F. 
Published: May 2023

AbstractIntroductionFollowing approval in 2009 of vagus nerve stimulation (VNS Therapy) for drug‐resistant epilepsy (DRE) in the Russian Federation, this is the first multicenter study across Russia to evaluate the safety and efficacy of adjunctive VNS Therapy.MethodsThe retrospective, observational registry included 58 pediatric patients with DRE (5–17 years old at implantation) who had ≥2 years of VNS. To ensure a robust evaluation process, changes in seizure frequency were evaluated for all seizure types as well as “most disabling” seizures (defined as seizures accompanied by falls, physical trauma, and/or incontinence in the absence of preventative measures).ResultsWith 2 years of VNS Therapy, 37 of 49 patients (76%) experiencing the most disabling epileptic seizures had a >50% decrease in frequency of such seizures, and 16 (33%) reported no longer experiencing the “most disabling” seizure type. In addition, based on the McHugh Outcome scale, VNS Therapy had a positive outcome on both frequency and severity of all epileptic seizure types, with a >50% decrease in frequency of all epileptic seizure types noted in 37 of 58 patients (64%), and 31% of patients had a Class I outcome, including 11 patients (19%) who achieved seizure freedom. VNS Therapy also had a positive effect on the frequency of status epilepticus: 13 patients (22%) had status epilepticus prior to implantation with a mean rate of 9.4 ± 17.7 events per year (range, 0–52), and after VNS Therapy, only one patient continued to experience status epilepticus (at 1 event per 4–6 months). VNS Therapy had an acceptable safety profile and no adverse events leading to VNS discontinuation were reported.ConclusionsThe results demonstrate that VNS Therapy is being safely and effectively applied to pediatric patients in the Russian healthcare system.
Determination of Thermal Time Constant of a Pt100 Temperature Sensor in Still Oil Using the Time Derivative Method
Authors: Dzinavatonga Kaitano , Obileke KeChrist , Makaka Golden , Mukumba Patrick , Munyaradzi Nyambo Benny 
Published: May 2023

AbstractAn alternative method was developed to determine the thermal time constant of a relatively cumbersome temperature sensor in still oil. A relationship between the take‐off gradient, initial temperature, thermal time constant, and final steady‐state temperature was deduced. An experiment was then performed using a Pt100 temperature sensor to test the veracity of the relationship. The Pt100 temperature sensor was subjected to five different step changes in temperature from an initial temperature of 60 °C. This resulted in five exponential curves with five different take‐off gradients. The linearization method was used to determine the thermal time constant as a control experiment. The new method was then applied to the same data set. It agrees very well with the linearization method within the limits of experimental error.
Trapping the Short‐Chain Odd Carbon Number Olefins Using Nickel(II)‐Catalyzed Tandem Ethylene Oligomerization and Friedel‐Crafts Alkylation of Toluene
Authors: Zubkevich Sergey V. , Tuskaev Vladislav A. , Gagieva Svetlana Ch. , Pavlov Alexander A. , Khrustalev Victor N. , Wang Fei , Pan Li , Li Yuesheng , Saracheno Daniele , Vikhrov Anton A. , Zarubin Dmitry N. , Bulychev Boris M. 
Published: May 2023

Comprehensive SummaryNickel(II) complexes with pyrazole‐based ligands are widely employed in catalysis of ethylene oligomerization and subsequent Friedel‐Crafts alkylation of toluene. We have prepared ten new nickel(II) dibromide complexes with various substituted bis(azolyl)methanes. They have been characterized using 1H NMR, IR, high resolution mass spectrometry and elemental analysis. The structures of three complexes have been unambiguously established using X‐ray diffraction. It was found that these complexes in the presence of Et2AlCl or Et3Al2Cl3 are active both in ethylene oligomerization and Friedel‐Crafts alkylation processes (activity up to 3720 kgoligomer·mol[Ni]−1·h−1). The use of Et3Al2Cl3 results in a higher share of alkylated products (up to 60%). Moreover, catalytic systems activated with Et3Al2Cl3 produced small amounts of odd carbon number olefins (up to 0.8%). The Friedel‐Crafts alkylation was used as a trap for previously undetected short‐chain odd carbon number olefins (C3 and C5).
Hybridization of the Pharmacophoric Features of Discoipyrrole C and Combretastatin A‐4 toward New Anticancer Leads
Authors: Kurian Jais , Ashtam Anvesh , Kesavan Akila , Chaluvalappil Saheer V. , Panda Dulal , Manheri Muraleedharan K. 
Published: May 2023

AbstractPharmacophore hybridization is an attractive strategy to identify new leads against multifactorial diseases such as cancer. Based on literature analysis of compounds possessing ‘vicinal diaryl’ fragment in their structure, we considered Discoipyrroles A−D and Combretastatin A‐4 (CA‐4) as possible components in hybrid design. Discoipyrrole C (Dis C) and CA‐4 were used as reference compounds in these studies and their hybrids, in the form of 4,5‐diaryl‐1H‐pyrrol‐3(2H)‐ones, were synthesized from suitable amino acid precursors though their ynone intermediates. Of these, the hybrid having exact substitution pattern as that of CA‐4 showed better potency and selectivity than Dis C, but its activity was less compared to CA‐4. This new analog disrupted interphase microtubules by inhibiting tubulin assembly by binding to the colchicine site, induced multipolar spindles, caused cell cycle block and apoptosis in HeLa cells. It also inhibited colony formation and migration of breast cancer cell lines.
A convolutional neural network‐based, quantitative complete blood count scattergram‐mapping framework promptly screens acute promyelocytic leukemia with high sensitivity
Authors: Liao Hongyan , Xu Yuanxin , Meng Qiang , Mao Zhigang , Qiao Yifan , Liu Yan , Zheng Qin 
Published: May 2023

AbstractBackgroundAcute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia (AML) characterized by its rapidly progressive and fatal clinical course if untreated, although it is curable if treated in a timely manner. Promptly screening patients who have results that are suspicious for APL is vital to overcome early death.MethodsThe authors developed an innovative framework consisting of ResNet‐18, a convolutional neural network architecture, with the objective of quantitatively mapping a complete blood count (CBC) scattergram to quickly and robustly indicate a probable susceptibility to APL. Three hundred and twenty scattergrams of the white blood cell differential channel from 51 patients with APL, 510 scattergrams from 105 patients who had non‐APL AML, and 320 scattergrams from 320 healthy controls were randomly stratified at a ratio of 4:1 and split into training and testing data sets to accomplish five‐fold cross‐validation.ResultsBoth the area under the curve and the average precision of >0.99 were achieved in each fold. Three hundred four of the 320 APL scattergrams (95%) were correctly flagged by the model, which outcompeted the CBC review rules recommended by the International Society of Laboratory Hematology (all p < .001). External validation based on an independent testing data set that included 56 scattergrams from 31 patients with APL, 56 scattergrams from 55 patients with non‐APL AML, and 64 scattergrams from 64 healthy controls also confirmed the sensitivity and specificity of the framework.ConclusionsTo the authors’ knowledge, their convolutional neural network‐based framework is the first to use scattergram output from routine CBC analysis to map suspicious APL early with outstanding sensitivity, specificity, and precision. The authors also describe a new CBC workflow incorporating this framework upstream of the morphologic review, which would provide the earliest flag for APL.Plain Language Summary

The authors propose an innovative way to visualize complete blood counts (CBCs) by mapping the difference in white blood cell counts using automated CBC analysis to identify potential acute promyelocytic leukemia (APL) using a convolutional neural network (CNN), which can eliminate the potential pitfalls of manual observation.

Analyses of an unprecedented, realistic data set validated that the quantitative relationship between the CBC scattergram and an APL abnormality is highly consistent.

This is the first study to date focusing on screening for APL using scattergrams of the difference in white blood cell counts from routine CBC tests and has significant clinical relevance.

The authors recommend using this method even before analyzing cell images, which could provide the earliest way to screen for APL in a sensitive and accurate way.
Single‐phase current‐fed switched‐capacitor five‐level inverter
Authors: Chen Shaojun , Ye Yuanmao , Wang Xiaolin , Ni Qiang 
Published: May 2023

SummaryWith an input‐side boost inductor, current source inverter (CSI) naturally has the unique performance of voltage boosting and continuous input current, but its switching devices need to have reverse blocking capability. Switched‐capacitor (SC) multilevel inverter (MLI) features self‐balancing capacitor voltages and flexible structure, but it suffers the problems of inrush charging current of capacitors and pulse input current. By combining the CSI's input characteristics and the SC‐MLI's output features, this work presents a new five‐level inverter. Its input current is continuous, and there is no inrush current. In addition, the voltage gain is improved to 2/(1−d), where d is the duty ratio of the inductor's charging mode. With the unique structure, the duty ratio ranges from 0 to 1, and it is independent of the modulation ratio of the inverter. This makes the control more flexible. In addition to topology, operation, and modulation, parameter design, power loss, and comparison study are analyzed in detail. Finally, simulation results with fuel cell as input, and experimental results are provided to verify the superior performance of the proposed inverter.