bluuebunny/crossref_metadata_2025_split huggingface dataset:
Autoimmune hepatitis and overlap syndrome among Alaska Native people: Prevalence, clinical characteristics, and remission
Authors: Johnston Janet M. , McMahon Brian , Townshend‐Bulson Lisa , Plotnik Julia , Jain Paarth , Judge Meggan , Rhodes Wileina , Homan Chriss 
Published: July 2023

AbstractBackground and AimHigh autoimmune hepatitis (AIH) and overlap syndrome (OS) prevalence have been previously documented among Alaska Native people. The purpose of this project is to report changes in AIH/OS prevalence over time, clinical characteristics, and factors associated with biochemical remission.MethodsWe reviewed medical records for Alaska Native/American Indian (AN/AI) patients diagnosed with AIH/OS between 1984 and 2021. Point prevalence was calculated based on AIH/OS patients alive at the end of 2021 and at 5‐year intervals from July 1, 2000, to July 1, 2020.ResultsWe identified 189 AN/AI persons diagnosed with AIH or OS (157 AIH, 32 OS). Of these 189, 137 were alive at the end of 2021 for a point prevalence of 91.2 per 100 000 (95% confidence interval [CI]: 77.2–107.8)—75.9 (95% CI: 63.2–91.2) for AIH and 15.3 (95% CI: 10.2–23.0) for OS. Prevalence for both AIH and OS has risen steadily since 2000. Eighty‐nine consented participants (62.7%) achieved biochemical remission with a median time from diagnosis to start of remission of 1.9 years (IQR 0.5–5.0 years). Consented patients with fatty liver were less likely to achieve remission, but their time to remission was shorter than for patients without fatty liver.ConclusionThe AN/AI population in Alaska continues to have the highest reported prevalence of AIH/OS in the world, with prevalence rising steadily since 2000. High reported AIH/OS prevalence is likely due in part to strong referral networks for liver disease. Detection and treatment can lead to biochemical remission and improved health outcomes.
Switching from entecavir to tenofovir alafenamide for maintaining complete virological response in chronic hepatitis B
Authors: Ishido Shun , Tamaki Nobuharu , Uchihara Naoki , Suzuki Keito , Tanaka Yuki , Miyamoto Haruka , Yamada Michiko , Matsumoto Hiroaki , Nobusawa Tsubasa , Keitoku Taisei , Takaura Kenta , Tanaka Shohei , Maeyashiki Chiaki , Yasui Yutaka , Takahashi Yuka , Tsuchiya Kaoru , Nakanishi Hiroyuki , Itakura Jun , Kurosaki Masayuki , Izumi Namiki 
Published: July 2023

AbstractBackground and AimHepatocellular carcinoma development can be decreased by achieving and maintaining complete virological response (CVR) in chronic hepatitis B. However, it is unclear whether switching from entecavir (ETV) to tenofovir alafenamide (TAF) could achieve and maintain CVR in patients with low‐level viremia (LLV; HBV DNA ≤ 3.3 log IU/mL) or occasional detectable HBV DNA during ETV treatment. Therefore, we aimed to examine whether the switching from ETV to TAF is effective in achieving CVR in patients with LLV or occasional detectable HBV DNA.MethodsThis study comprised 45 patients who switched from ETV to TAF. All patients received ETV and TAF for >2 years, and the HBV DNA levels were measured every 3 months. Maintaining undetectable HBV DNA during 2‐year period is defined as CVR. The primary endpoint is the CVR rate during ETV and TAF treatment.ResultsThe CVR rate for each of the 2 years of ETV and TAF therapy was 33.3% (15/45) and 68.9% (31/45, P < 0.01), respectively, and the CVR rate increased by switching from ETV to TAF. In patients with occasional detectable HBV DNA during ETV treatment (22 patients), 15 achieved CVR and 7 maintained occasional detectable HBV DNA. In patients with LLV during ETV treatment (eight patients), three achieved CVR and five had occasional detectable HBV DNA.ConclusionSwitching from ETV to TAF increases the CVR rate in patients with LLV or occasional detectable HBV DNA and could be an alternative treatment option.
Effect of perfluorotetradecanoic acid on the morphology of a photopolymerizable phospholipid monolayer at the air‐water interface
Authors: Yeboah Alfred , Paige Matthew F. 
Published: July 2023

AbstractFundamental physical chemical properties of a monolayer film comprised of the chiral, photopolymerizable phospholipid 1,2‐bis(10,12‐tricosadiynoyl)‐sn‐glycero‐3‐phosphocholine (Diyne PC) and the impact of a model perfluorocarbon, perfluorotetradecanoic acid (PF), on these film properties have been investigated, both with and without UV photopolymerization. Enantiomerically pure Diyne PC formed compact, stable monolayers at the air‐water interface, exhibited typical phospholipid phase transitions in surface pressure‐area isotherms and yielded micron‐scale, linear domains upon film compression. Photopolymerized films were significantly more expanded in comparison with the unpolymerized films and the resulting domains had a spiral morphology with a strongly preferred spiral direction. Mixing Diyne PC with PF altered the isotherm behavior, with the principal effects being a significant reduction in the plateau region associated with the characteristic LE‐LC phase transition and no larger‐scale spiral domain formation in the monolayers of the mixed films. Results are discussed in the context of interactions between the two different film components and the tendency of perfluorinated surfactants to disperse condensed phase regions of phospholipid‐based monolayer films. Overall, the tendency of PF to disperse condensed regions of the film makes patterning of films in mixed phospholipid‐perfluorocarbon monolayers particularly difficult.
Bacteriology of Different Phenotypes of Chronic Rhinosinusitis
Authors: Li Yu‐Ting , Huang Shuang‐Shuang , Ma Jia‐Hung , Hsieh Bing‐Han , Tsou Yung‐An , Lin Chia‐Der , Tai Chih‐Jaan , Shih Liang‐Chun 
Published: July 2023

ObjectivesChronic rhinosinusitis (CRS) reduces the health‐related quality of life and subsequently causes a tremendous socio‐economic impact. Although many studies have been conducted, few have identified a relationship between bacteriological characteristics and different phenotypes or endotypes. Therefore, this study aimed to elucidate the recent trends in bacterial cultures from different types of CRS in the Asian population.MethodsThis retrospective case–control study recruited patients diagnosed with CRS who underwent functional endoscopic sinus surgery (FESS) at a tertiary hospital in Taiwan. The patients were classified into those with chronic rhinosinusitis with nasal polyps (CRSwNP)/chronic rhinosinusitis without nasal polyps (CRSsNP), eosinophilic chronic rhinosinusitis (eCRS)/non‐eosinophilic chronic rhinosinusitis (NECRS), and central compartment atopic disease (CCAD)/lateral‐dominant nasal polyp (LDNP) groups. The demographic data and bacteriological characteristics of the groups were analyzed.ResultsWe included 503 patients, identifying no significant difference between CRSwNP and CRSsNP for several common bacteria in CRS. The number of Staphylococcus epidermidis isolates in culture was significantly higher in the NECRS group (50.46% vs. 32.56%, p = 0.0003) than that in the eCRS group. The number of methicillin‐resistant Staphylococcus aureus (MRSA; 8.51% vs. 2.35%, p = 0.0221) positive isolates was significantly higher in the CCAD group than that in the LDNP group.ConclusionsThis was the first study in Asia to analyze the relationship between bacteriological characteristics and CCAD. MRSA is significantly higher in the CCAD group than that in the LDNP group. Recognizing the unique microbiology of CRSwNP, eCRS, and CCAD is crucial when selecting antimicrobial therapy to lessen the socio‐economic impact.Level of Evidence3 Laryngoscope, 134:1071–1076, 2024
On designing and developing single‐step second‐order implicit methods with dissipation control and zero‐order overshoots via subsidiary variables
Authors: Li Jinze , Li Hua , Lian Yiwei , Yu Kaiping , Zhao Rui 
Published: July 2023

AbstractHilber and Hughes gave several competitive demands on the implicit methods in 1978. However, there are no such integration methods in the traditional algorithm design. Via imposing subsidiary variables, this article proposes two novel implicit methods to splendidly achieve these competitive demands without increasing computational costs. The two novel methods are self‐starting, unconditionally stable, single‐solve, identically second‐order accurate, controllably dissipative, and non‐overshooting. The novel methods achieve the maximal dissipation of auxiliary variables in the high‐frequency limit, although such the design is not a must. The first novel method uses auxiliary velocity and acceleration variables, whereas the second one employs two auxiliary acceleration variables. After embedding desired numerical characteristics, the novel methods employ four eigenvalues of amplification matrices in the high‐frequency limit as user‐specified parameters to flexibly control numerical high‐frequency dissipation. To reduce the number of use‐specified parameters, this article gives some recommended sub‐families of algorithms, such as optimal low‐frequency dissipation schemes. The article further refines the error analysis to analytically calculate amplitude and phase errors for some implicit methods. The error analysis technique can be applied to almost all direct time integration methods. Comparisons of amplitude and phase errors highlight the superiority of the novel methods over the published algorithms. In addition, some classical measures, such as numerical damping ratios and relative period errors, are analyzed and compared. Numerical examples are solved to show the novel methods' superiority.
Resonance Interaction Due to Quantum Coherence
Authors: Hu Jiawei , Yu Hongwei 
Published: July 2023

AbstractThe interaction energy between two atoms is crucially dependent on the quantum state of the two‐atom system. In this paper, it is demonstrated that a steady resonance interaction energy between two atoms exists when the atoms are in a certain type of coherent superposition of single‐excitation states. The interaction is tree‐level classical in the sense of the Feynman diagrams. A quantity called quantum classicality is defined in the present paper, whose nonzero‐ness ensures the existence of this interaction. The dependence of the interatomic interaction on the quantum nature of the state of the two‐atom system may potentially be tested with Rydberg atoms.
Facile Construction of Nanostructured Cermet Anodes with Strong Metal–Oxide Interaction for Efficient and Durable Solid Oxide Fuel Cells
Authors: Wang Baisen , Yue Zhongwei , Chen Zhiyi , Zhang Yanxiang , Fang Huihuang , Ai Na , Wang Ruijing , Yang Fan , Guan Chengzhi , Jiang San Ping , Shao Zongping , Luo Yu , Chen Kongfa 
Published: July 2023

AbstractNanostructured anodes generate massive reaction sites to oxidize fuels in solid oxide fuel cells (SOFCs); however, the nonexistence of a practically viable approach for the construction of nanostructures and the retention of these nanostructures under the harsh operating conditions of SOFCs poses a significant challenge. Herein, a simple procedure is reported for the construction of a nanostructured Ni–Gd‐doped CeO2 anode based on the direct assembly of pre‐formed nanocomposite powder with strong metal–oxide interaction. The directly assembled anode forms heterointerfaces with the electrolyte owing to the electrochemical polarization current and exhibits excellent structural robustness against thermal ripening. An electrolyte‐supported cell with the directly assembled anode produces a peak power density of 0.73 W cm−2 at 800 °C, while maintaining stability for 100 h, which is in contrast to the drastic degradation of the cermet anode prepared using the conventional method. These findings provide clarity on the design and construction of durable nanostructured anodes and other electrodes for SOFCs.
Can the digital economy promote fiscal effort?: Empirical evidence from Chinese cities
Authors: Zhang Wei-Liang , Song Li-Ying , Ilyas Muhammad 
Published: July 2023

AbstractOver the last few years, the governments’ fiscal revenue and expenditure have been significantly affected by the rapid growth of global digital economy. Despite the significant role that digital economy plays in improving the ability of the government to generate fiscal revenue, there is relatively little empirical evidence of this. Therefore, this study aims to reveal the impact of digital economy on the urban fiscal effort of China by analyzing the data recorded from 2011 to 2019. According to the empirical findings, digital economy can significantly improve the level of fiscal effort. Meanwhile, digital economy has a significant nonlinear effect on fiscal effort. As suggested by the results of expansion analysis, the effect of digital economy on fiscal effort shows significant regional heterogeneity and the spatial spillover effect is positive. Based on the findings of this study, it is recommended to strengthen the construction of digital infrastructure, optimize the practice of fiscal revenue management under the context of digital economy, and improve the governments’ fiscal situation by paying attention to the coordinated development of digital economy among various regions.
Escherichia coli high-risk clone ST410 harboring blaNDM-13 isolated from hospital wastewater in China
Authors: Ju Xiaoyang , Wu Yuchen , Chen Gongxiang , Zhang Rong 
Published: July 2023

AbstractA carbapenem-resistant Escherichia coli strain C-SRM-3 was isolated from hospital wastewater effluent in Hangzhou city, China in March 2022. Analysis of the whole genome sequence showed that this blaNDM-13-positive strain belonged to an internationally recognized high-risk clone ST410 responsible for the dissemination of carbapenem resistance in E. coli. This isolate displayed a multidrug-resistant phenotype and carried a cassette of antibiotic-resistant genes. blaNDM-13 gene was successfully transferred to the recipient E. coli C600 via conjugation. WGS results revealed that blaNDM-13 gene was located on an IncI1 type plasmid replicon. The phylogenetic reconstruction showed that wastewater-sourced C-SRM-3 strain was located in a single branch, far removed from human-derived and animal-sourced isolates. The detection of blaNDM-13 in hospital wastewater suggests that continuous monitoring of antibiotic-resistant genes in the environment is critical for the prevention of carbapenem-resistant bacteria spreading.
Fed dairy cattle market reporting: Changing marketing methods, regional variation, and hedonic modeling
Authors: Schroeder Ted C. , Tonsor Glynn T. , Coffey Brian K. 
Published: July 2023

AbstractFed dairy cattle represent an important and growing component of the U.S. fed cattle market. However, little is known about factors affecting fed dairy cattle transaction prices. This study analyzes confidential transaction-level data collected by United States Department of Agriculture Agricultural (USDA) Marketing Service (AMS) under Livestock Mandatory Reporting to determine how data collected for price reporting explains price variation. Hedonic models are developed to illustrate potential use to enhance fed dairy cattle price reporting. However, important price variation remains unexplained suggesting factors not available in AMS data are associated with fed dairy cattle price variation. We suggest AMS collect and utilize additional data to enhance price reporting.
How the Italian Formula 1 Grand Prix 2022 Mass Gathering Event Compares to the Arbon Model: A Descriptive Study
Authors: Paleari Andrea , Spina Stefano , Marrazzo Francesco , Ripoll Alba , Volontè Fabio , Greco Gianluca , Zoli Alberto , Sechi Giuseppe Maria , Saggiante Diego , Chiodini Gianluca , Stucchi Riccardo , Fumagalli Roberto 
Published: July 2023

Abstract

Objective:
To describe the health-care resources implemented during the Italian Formula 1 Grand Prix (F1GP) and to calculate the patient presentation rate (PPR) based on both real data and a prediction model.

Methods:
Observational and descriptive study conducted from September 9 to September 11, 2022, during the Italian F1GP hosted in Monza (Italy). Maurer’s formula was applied to decide the number and type of health resources to be allocated. Patient presentation rate (PPR) was computed based on real data (PPR_real) and based on the Arbon formula (PPR_est).

Results:
Of 336,000 attendees, n = 263 requested medical assistance with most of them receiving treatment at the advanced medical post, and n = 16 needing transport to the hospital. The PPR_real was 51 for Friday, 78 for Saturday, 134 for Sunday, and 263 when considering the whole event as a single event. The PPR_est resulted in 85 for Friday, 93 for Saturday, 97 for Sunday, and 221 for the total population.

Conclusions:
A careful organization of health-care resources could mitigate the impact of the Italian F1GP on local hospital facilities. The Arbon formula is an acceptable model to predict and estimate the number of patients requesting medical assistance, but further investigation needs to be conducted to implement the model and tailor it to broader categories of MGE.
Sustainability performance and sustainability reporting in SMEs: a love affair or a fight?
Authors: Galli Davide , Torelli Riccardo , Caccialanza Andrea 
Published: July 2023

AbstractThis research aims to analyse the links and potential limiting and supporting factors between sustainability actions and sustainability reporting. Comparing companies involved in sustainability actions and those whose reporting practices lack a formal reporting system, this analysis focuses on Italian small and medium-sized enterprises (SMEs) in the meat and cured meat industry, identifying the perspective (formative) that links sustainability action to communication in these SMEs. The qualitative interpretative approach, based on semistructured interviews, highlights the relevant strengths and weaknesses concerning substantive sustainability actions and the effect of communication on them, providing implications for international and sectoral policies and management choices. Filling a gap in the SME literature concerning their approaches to sustainability reporting and action (and the relationship thereof), this study also introduces, as a widely used practice, ‘greenhushing’, i.e., the deliberate absence of or limited communication on effectively implemented sustainability practices or their salient results.
Session-by-session change in misophonia: a descriptive case study using intensive CBT
Authors: Gregory Jane , Foster Chloe 
Published: July 2023

Abstract
There is preliminary evidence that CBT may be helpful for improving symptoms of misophonia, but the key mechanisms of change are not yet known for this disorder of decreased tolerance to everyday sounds. This detailed case study aimed to describe the delivery of intensive, formulation-driven CBT for an individual with misophonia and report on session-by-session outcomes using a multi-dimensional measurement tool (SFive). The patient was offered 12 hours of treatment over five sessions, using transdiagnostic and misophonia-specific interventions. Reliable and clinically significant change was found from baseline to one-month follow-up. Visual inspection of outcome graphs indicated that change occurred on the ‘outbursts’ and ‘internalising appraisals’ SFive subscales following assessment, and on the ‘emotional threat’ subscale after the first treatment session. The other two subscales started and remained below a clinically significant level. The biggest symptom change appeared to have occurred after the second session, which included interventions engaging with trigger sounds. The results demonstrated the individualised nature of misophonia, supporting the use of individually tailored treatment for misophonia and highlighting the importance of using a multi-dimensional measurement tool.

Key learning aims

(1)
To understand misophonic distress from a CBT perspective.

(2)
To learn a formulation-driven approach to misophonia.

(3)
To apply transdiagnostic interventions to misophonia.

(4)
To learn about misophonia-specific interventions.

(5)
To consider the value of a multi-dimensional measure of misophonia.
Enhanced Mixing and Reaction in Converging Flows: Theory and Pore‐Scale Imaging
Authors: Izumoto Satoshi , Heyman Joris , Huisman Johan Alexander , De Vriendt Kevin , Soulaine Cyprien , Gomez Francesco , Tabuteau Hervé , Méheust Yves , Le Borgne Tanguy 
Published: July 2023

AbstractMixing fronts at the interface of opposing flows are compressed at a constant rate. The resulting exponential stretching of fluid elements leads to enhanced chemical gradients and biogeochemical processes. This process is similar as what occurs in the pore space of 3D chaotic flows. However, it is so far not known how such fluid compression controls the amplitude of mixing and reaction rates in porous media. Here we derive analytical predictions for the mixing width, the maximum reaction rate and the reaction intensity in compressed mixing fronts as a function of the Péclet and Damköhler numbers. We developed an experimental setup providing pore scale measurements of mixing and reaction rates in mixing fronts at the interface of converging flows. The theory accurately predicts the scaling of mixing and reaction with the Péclet number both in porous micromodels and simple Hele‐Shaw cells. Additionally, we found that the presence of pore scale heterogeneities in the porous micromodels enhances reaction rates by a factor of 4 compared to the Hele‐Shaw cells. Using numerical simulations of pore scale velocity fields, we attributed this phenomenon to the enhancement of pore‐scale compression due to the presence of grains in accelerating flows. These findings provide new insights into the dynamics of mixing‐induced reactions in porous media.
Identification and fixing bottlenecks of a food manufacturing system using a simulation approach
Authors: Javadi Seyed Mahdi , Sadjadi Seyed Jafar , Makui Ahmad 
Published: July 2023

AbstractIn manufacturing systems, simulation modeling plays an important role in creating some changes instead of working on real systems. Manipulation in a real system is more costly than manipulation in a simulated model. In this research, we tried to use a simulation approach to recognize and minimize bottlenecks of a production line, which will decrease costs and improve productivity. To achieve our objectives, we chose a case and analyzed its production line. By using our case study strategy, we tried to collect our data and adapt a conceptual model of production processes drawing on an operation process chart (OPC). After that, we created a simulation model of the production processes by using the popular Arena simulation software 13.5. By running the Arena model, some bottlenecks were found. Ultimately, we proposed some solutions to obviate bottlenecks and reduce the total costs of production.