bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lithiophilic Cu3Sn Modified Cu Foil as Current Collector for Stable Lithium Metal Anodes
Authors: Ma Kaiwen , Li Fangya , Li Xinbin , Liu Ting , Wang Ting , Wang Huanlei , Liu Shuai 
Published: August 2023

AbstractThe development of lithium metal battery is severely restricted by its uncontrolled dendrite growth and volume change. In this work, we designed a controllable lithiophilic Cu3Sn modified commercial Cu foil as current collector via simple industrial electroplating and heat treatment. As a Li‐reservoir substrate for efficient deposition/stripping of Li metal, the introduction of Cu3Sn not only increases multiple active sites for the deposition of Li, but also provides more transfer paths for lithium ions. The Li metal anodes prepared by molten Li on the Cu current collector with dispersed Cu3Sn active sites provide a uniform lithiophilic surface, which could effectively promote a uniform Li deposition/stripping and suppress the formation of lithium dendrites. As a result, the assembled symmetric battery is stable at a low over‐point position for 1600 h without short circuit at 1 mA cm−2 with 1 mAh cm−2, the full battery paired with LiFePO4 still maintains a high‐capacity retention rate of 97.1 % and a coulombic efficiency (CE) of 99.5 % after 400 cycles at a current density of 2 C. This work provides a facile and controllable strategy for the design of current collectors with high lithium affinity for stable lithium metal anode applications.
Synthesis of Nano‐zero‐valent Iron/Chitosan based on Bimetallic Nanoparticles for the Simultaneous Removal of Reactive Violet 5 and Reactive Blue 171 from Aquatic Media: Response Surface Methodology
Authors: Neishaboori Fahimehsadat Mostafavi , Sohrabi Mahmoud Reza , Motiee Fereshteh , Davallo Mehran 
Published: August 2023

AbstractIn this study, a nanostructure adsorbent was fabricated from mixed nanosized zero‐valent iron (nZVI), chitosan (CS), and copper (Cu) for the simultaneous removal of Reactive Violet 5 and Reactive Blue 171 from the aqueous media. The prepared adsorbent was characterized by scanning electron microscopy, energy‐dispersive X‐ray spectroscopy, Brunauer‐Emmett–Teller, Fourier transform infrared spectroscopy, and X‐ray diffraction. The impact of variables, including pH, adsorbing dosage, contact time, and temperature on the removal percentages of RV5 and RB171 dyes were simultaneously investigated using response surface methodology (RSM) based on a central composite design. The maximum removal efficiency (77.67 %) was obtained at a pH of 3, an adsorbent dosage of 0.3 g, a contact time of 15 min, and a temperature of 10 °C. The adsorption process fitted well with the Langmuir isotherm model with a coefficient of determination (R2) equal to 0.9996 and the pseudo‐second‐order kinetic model (R2=0.9988). Hence, it could be concluded that the process of adsorption mechanism is monolayer and chemical. The maximum adsorption capacity (qmax) was 50.25 mg g−1. In conclusion, nZVI‐CS‐Cu can be considered as an efficient and inexpensive adsorbent for dye removal from aqueous solutions, because its separation is quick and easy, it possesses high efficiency, and there is no secondary pollution.
Synthesis of 2’,4‐Dibromo‐2,4’‐bithiazole Using Novel Long‐range Halogen Dance Reaction
Authors: Arimitsu Kenji , Hirokawa Yoshimi , Ikegawa Yuriko , Tanba Akiko , Ueda Yuki , Kashihara Taiga , Atarashi Naruhiro , Yoshida Ryoto , Matsuo Yosuke , Maezaki Naoyoshi 
Published: August 2023

AbstractThis study presents a novel halogen dance reaction using 4,5‐dibromo‐2,4’‐bithiazole, which demonstrates a long‐range effect. The reaction involves the migration of a bromo group from the C5‐position to the C2’‐position of another thiazole ring when treated with lithium hexamethyldisilazide (LiHMDS), resulting in the formation of a non‐symmetric brominated bithiazole. In contrast, the base‐induced C2’‐bromination of 4‐bromobithiazole was found to be inefficient in synthesizing the desired brominated bithiazole due to its poor deprotonation selectivity.
Missed chances and unfulfilled hopes: Why do firms make errors in evaluating technological opportunities?
Authors: Kumar Amit , Operti Elisa 
Published: August 2023

AbstractResearch AbstractThis study examines commission and omission errors in the evaluation of technological opportunities. Integrating structural and cognitive perspectives, we propose that inventors with more cohesive collaboration networks within the firm or geographically closer to the corporate headquarters exert greater influence on the dominant representations shaping opportunity evaluation within the firm. Thus, their inventions are more likely to be positively assessed, even if quality considerations suggest otherwise. Conversely, even when superior in quality, inventions from individuals with less cohesive collaboration networks within the firm or located far from the corporate headquarters are less likely to be positively evaluated, leading to omission errors. The study provides evidence based on 22 interviews and archival data from the mobile phone and personal digital assistant industry between 1990 and 2010.Managerial AbstractThis study examines commission and omission errors in decision‐making about technologies. Studying patent renewal decisions of 42 firms in the mobile phone and personal digital assistant industry between 1990 and 2010, we show that inventors with more cohesive collaboration networks within the firm or located close to the corporate headquarters have their inventions positively assessed even when of lower quality, leading to commission errors. On the other hand, inventors with less cohesive collaboration networks within the firm or located far away from the corporate headquarters have their inventions disregarded even when of higher quality, causing omission errors. These findings call for managerial vigilance in technology evaluation decisions, ensuring valuable ideas are not overlooked due to an inventor's network position or location.
Engineered Extracellular Vesicles to Enhance Antigen Presentation for Boosting Light‐Driven Tumor Immunotherapy
Authors: Li Xuyu , He Shuaicheng , Luo Ban , Li Puze , Chen Xue , Wu Meichan , Song Cheng , Liu Chao , Yang Tian , Zhang Xiaojuan , Yang Xiangliang , Hu Jun 
Published: August 2023

AbstractExtracellular vesicles (EVs) have emerged as potential tools for tumor‐target therapy accompanied with activating anticancer immune responses by serving as an integrated platform, but usually suffered from the limited cross presentation of tumor‐associated antigen by dendritic cells (DCs). Here, a straightforward engineering strategy to construct heat shock proteins 70 (HSP70) highly expressed EVs incapsulated with Te nanoparticles (Te@EVsHSP70) for tumor photothermal therapy triggering improved immunotherapy is proposed. Tumor cells are firstly used as bioreactors for intracellular synthesis of Te nanoparticles, and NIR irradiation is subsequently introduced to upregulate the expression of HSP70 to give engineered Te@EVsHSP70 through exocytosis. Te@EVsHSP70 exhibits excellent photothermal performance and enhanced tumor antigen capture capability, which induces significant immunogenic death of tumor cells and improves DCs maturation both in vitro and in vivo. Thus, the engineered EVs demonstrate superior antitumor efficacy through photothermal effect and following provoked antitumor immune responses. This work provides a facile method to fabricate multifunctional EVs‐based drug delivery system for improving photothermal‐triggered tumor immunotherapy.
Gaining Deep Understanding of Electrochemical CO2RR with In Situ/Operando Techniques
Authors: Gong Yue , He Tao 
Published: August 2023

AbstractElectrocatalysis for CO2conversion has been extensively studied to mitigate the energy shortage and environmental issues, which are gaining ever‐increasing attention. However, the complicated CO2reduction process and the dynamic evolution occurring on electrocatalyst surface make it hard to understand the catalytic mechanism. The development of advanced in situ/operando techniques intelligently coupled with electrochemical cells sheds light on the related study via capturing surface atomic rearrangement, tracing chemical state change of catalysts, monitoring the behavior of intermediates and products, and depicting microenvironment near the electrode surface. In this review, fundamentals of the state‐of‐the‐art in situ/operando techniques are clarified first. Case studies on the in situ/operando techniques performed to probe the CO2reduction reaction processes are then discussed in detail. Finally, conclusions and outlook on this field are presented.
Sasa veitchii extract alleviates nonalcoholic steatohepatitis in methionine–choline deficient diet‐induced mice by regulating peroxisome proliferator‐activated receptor alpha
Authors: Yoshioka Hiroki , Wu Sixun , Moriishi Takeshi , Tsukiboshi Yosuke , Yokota Satoshi , Miura Nobuhiko , Yoshikawa Masae , Inagaki Naoki , Matsushita Yuki , Nakao Makoto 
Published: August 2023

AbstractAimNonalcoholic steatohepatitis (NASH) is a pandemic liver disease. This study aimed to explore the protective effects of Sasa veitchii extract (SE) in a mouse model of methionine–choline‐deficient (MCD) diet‐induced NASH.MethodsEight‐week‐old male C57BL/6J mice were fed a normal diet or an MCD diet for 8 weeks (0–8 weeks). SE (0.1 mL) was administered orally once daily for the latter period (4 weeks; 5–8 weeks). Body weight was measured weekly. The mice were euthanized and plasma samples were collected. Livers were collected and weighed.ResultsThe MCD diet decreased the liver/body weight ratio, elevated plasma alanine aminotransferase and aspartate aminotransferase levels, and increased liver oxidative stress, fibrosis, and inflammation. These changes were alleviated by SE administration. We also found that the MCD‐induced increase in triglycerides and lipid droplets in the liver was attenuated by SE. Furthermore, MCD‐induced glutathione peroxidase‐4 and peroxisome proliferator‐activated receptor‐alpha downregulation was sustained by SE administration.ConclusionOur results showed that SE protected mice against MCD‐induced hepatic injury, including oxidative stress and inflammation, by modulating peroxisome proliferator‐activated receptor alpha activation.
How Do OS and Application Schedulers Interact? An Investigation with Multithreaded Applications
Authors: Korndörfer Jonas H. Müller , Eleliemy Ahmed , Simsek Osman Seckin , Ilsche Thomas , Schöne Robert , Ciorba Florina M. 
Published: August 2023

AbstractScheduling is critical for achieving high performance for parallel applications executing on high performance computing (HPC) systems. Scheduling decisions can be taken at batch system, application, and operating system (OS) levels. In this work, we investigate the interaction between the Linux scheduler and various OpenMP scheduling options during the execution of three multithreaded codes on two types of computing nodes. When threads are unpinned, we found that OS scheduling events significantly interfere with the performance of compute-bound applications, aggravating their inherent load imbalance or overhead (by additional context switches). While the Linux scheduler balances system load in the absence of application-level load balancing, we also found it decreases performance via additional context switches and thread migrations. We observed that performing load balancing operations both at the OS and application levels is advantageous for the performance of concurrently executing applications. These results show the importance of considering the role of OS scheduling in the design of application scheduling techniques and vice versa. This work motivates further research into coordination of scheduling within multithreaded applications and the OS.
OpenBMB: Big Model Systems for Large-Scale Representation Learning
Authors: Zeng Guoyang , Han Xu , Zhang Zhengyan , Liu Zhiyuan , Lin Yankai , Sun Maosong 
Published: August 2023

AbstractBig pre-trained models (PTMs) have received increasing attention in recent years from academia and industry for their excellent performance on downstream tasks. However, huge computing power and sophisticated technical expertise are required to develop big models, discouraging many institutes and researchers. In order to facilitate the popularization of big models, we introduce OpenBMB, an open-source suite of big models, to break the barriers of computation and expertise of big model applications. In this chapter, we will introduce the core toolkits in OpenBMB, including BMTrain for efficient training, OpenPrompt and OpenDelta for efficient tuning, BMCook for efficient compression, and BMInf for efficient inference.
Bearing Capacity Prediction of Corroded PT Beams Incorporating Grouting Defects and Bond Degradation
Authors: Wang Lei 
Published: August 2023

AbstractCorrosion can reduce the sectional area of strand, induce concrete cracking, and degrade bond strength, which can further decrease the bearing capacity of prestressed concrete beams. First, an analytical model is proposed to predict the flexural bearing capacity of partially ungrouted post-tensioned concrete beams. Then, a prediction model of corroded prestressed concrete beams is established to calculate the incompatible deformation between strand and concrete under different load conditions.
Injecting the UV into the bootstrap: Ising Field Theory
Authors: Correia Miguel , Penedones João , Vuignier Antoine 
Published: August 2023

Abstract
We merge together recent developments in the S-matrix bootstrap program to develop a dual setup in 2 space-time dimensions incorporating scattering amplitudes of massive particles and matrix elements of local operators. In particular, the stress energy tensor allows us to input UV constraints on IR observables in terms of the central charge cUV of the UV Conformal Field Theory. We consider two applications: (1) We establish a rigorous lower bound on cUV of a class of ℤ2 symmetric scalar theories in the IR (including ϕ4); (2) We target Ising Field Theory by, first, minimizing cUV for different values of the magnetic field and, secondly, by determining the allowed range of cubic coupling and one-particle form-factor for fixed cUV = 1/2 and magnetic field.
Little string instanton partition functions and scalar propagators
Authors: Filoche Baptiste , Hohenegger Stefan 
Published: August 2023

Abstract
We discuss a class of Little String Theories (LSTs) whose low energy descriptions are supersymmetric gauge theories on the Ω-background with gauge group U(N) and matter in the adjoint representation. We show that the instanton partition function of these theories can be written in terms of Kronecker-Eisenstein series, which in a particular limit of the deformation parameters of the Ω-background organise themselves into Greens functions of free scalar fields on a torus. We provide a concrete identification between (differences of) such propagators and Nekrasov subfunctions. The latter are also characterised by counting specific holomorphic curves in a Calabi-Yau threefold XN,1 which engineers the LST. Furthermore, using the formulation of the partition function in terms of the Kronecker-Eisenstein series, we argue for new recursive structures which relate higher instanton contributions to products of lower ones.
𝒩 = 1 SCFTs from F-theory on Orbifolds
Authors: Giacomelli Simone , Savelli Raffaele 
Published: August 2023

Abstract
We study four-dimensional superconformal field theories living on the worldvolume of D3 branes probing minimally-supersymmetric F-theory backgrounds, focusing on the case of orbi-orientifold setups with and without 7-branes. We observe that these theories are closely related to compactifications of six-dimensional 𝒩 = (1, 0) theories on a torus with flux, where the flux quanta is mapped in Type IIB to the defining data of the orbifold group. We analyze the cases of class 𝒮k theories as well as of compactifications of the E-string and of orbi-instanton theories. We also classify 𝒮-fold configurations in F-theory preserving minimal supersymmetry in four dimensions and their mass deformations.
Hormonelle Kontrazeptiva bei Adoleszentinnen
Authors: Böttcher Bettina , Segerer Sabine 
Published: August 2023

ZusammenfassungDie hormonelle Kontrazeption in der Adoleszenz stellt weiterhin eine wichtige Verhütungsmöglichkeit dar, auch wenn sich ein Trend zur Pillenmüdigkeit und Pillenskepsis abzeichnet. Umso wichtiger ist eine ausführliche, patientinnenzentrierte Beratung über verschiedene Kontrazeptiva in der gynäkologischen Praxis. Gerade bei der Erstvorstellung junger Mädchen sollten verschiedene Verfahren mit ihren Vor- und Nachteilen diskutiert werden und gemeinsam mit dem Mädchen überlegt werden, welche Anforderungen und Wünsche an die Verhütungsmethode gestellt werden. Prinzipiell kommen in der Adoleszenz alle verfügbaren hormonellen Kontrazeptiva in Frage. Dieses gilt auch für langwirksame reversible Kontrazeptiva, insbesondere für Intrauterinsysteme. Die Vermeidung von Teenagerschwangerschaften, aber auch die Entwicklung einer selbstbestimmten Sexualität sollten bei der Beratung bedacht werden.
Pseudoneglect during object search in naturalistic scenes
Authors: Nuthmann Antje , Clark Christopher N. L. 
Published: August 2023

AbstractPseudoneglect, that is the tendency to pay more attention to the left side of space, is typically assessed with paper-and-pencil tasks, particularly line bisection. In the present study, we used an everyday task with more complex stimuli. Subjects’ task was to look for pre-specified objects in images of real-world scenes. In half of the scenes, the search object was located on the left side of the image (L-target); in the other half of the scenes, the target was on the right side (R-target). To control for left–right differences in the composition of the scenes, half of the scenes were mirrored horizontally. Eye-movement recordings were used to track the course of pseudoneglect on a millisecond timescale. Subjects’ initial eye movements were biased to the left of the scene, but less so forR-targets than forL-targets, indicating that pseudoneglect was modulated by task demands and scene guidance. We further analyzed how horizontal gaze positions changed over time. When the data forL- andR-targets were pooled, the leftward bias lasted, on average, until the first second of the search process came to an end. Even for right-side targets, the gaze data showed an early left-bias, which was compensated by adjustments in the direction and amplitude of later saccades. Importantly, we found that pseudoneglect affected search efficiency by leading to less efficient scan paths and consequently longer search times forR-targets compared withL-targets. It may therefore be prudent to take spatial asymmetries into account when studying visual search in scenes.
Targeted NGS on sequential bone marrow biopsies aids in the evaluation of cytopenias and monocytosis and documents clonal evolution—a proof of principle study
Authors: Nann Dominik , Rau Achim , Mahmutovic Lejla , Steinhilber Julia , Meca Vanessa , Federmann Birgit , Vogel Wichard , Bonzheim Irina , Quintanilla-Martinez Leticia , Fend Falko 
Published: August 2023

AbstractDifferential diagnosis of clonal versus reactive cytopenia and monocytosis, respectively, frequently presents a diagnostic challenge. With the two recent classifications of myeloid disorders, mutational analysis has gained importance as a diagnostic tool. However, reports on its utility on trephine bone marrow biopsies (BMB) are sparse. The aim of our proof of principle study was to determine the suitability of targeted sequencing for the longitudinal evaluation of cytopenia and monocytosis and demonstration of clonal evolution on sequential BMB. Seventy-seven EDTA-decalcified BMB of 33 patients with peripheral cytopenia and/or monocytosis, including at least one follow-up biopsy/patient, were included. Initial morphological diagnoses were idiopathic cytopenia of undetermined significance (ICUS, 8 cases), MDS (without blast increase, 7 cases), MDS with increased blasts/excess blasts (MDS-IB/EB) (11 cases), and CMML (7 cases). Thirty-one genes relevant for myeloid disorders were examined using two custom AmpliSeq NGS panels. Mutations were found in the initial BMB of 5/8 cases of ICUS, thus changing the diagnosis to clonal cytopenia of unknown significance (CCUS), 5/7 MDS, 10/11 MDS-IB/EB, and 7/7 CMML. Clonal evolution was observed in 14/33 (42%) cases, mostly associated with disease progression. None of the wild-type patients acquired mutations during follow-up. NGS-based mutation profiling is a robust diagnostic tool for BMB and provides valuable additional information, especially for cases with no/minimal dysplasia, and for better risk stratification of MDS. Tracking variant allele frequency and appearance of mutations over time allows for observing clonal evolution or relapse.
Construction and validation of a novel prognostic nomogram for predicting overall survival in lung adenocarcinoma patients with different patterns of metastasis
Authors: Xiong Ying , Gu Feifei , Cui Jin , Liu Yuting , Sun Min , Gu Xinyue , Zhong Luhui , Zhang Kai , Liu Li 
Published: August 2023

Abstract
Objective
Metastasis of lung cancer is an important factor affecting survival. The present study proposed to establish and verify a nomogram for predicting overall survival (OS) in lung adenocarcinoma (LUAD) patients with different patterns of metastasis.

Methods
A total of 9727 patients diagnosed with metastatic LUAD patients from 2010 to 2015 were enrolled based on surveillance, epidemiology and end results (SEER) Database and then randomly divided into training and validation cohorts, and 136 patients in our Cancer Center were enrolled as the external validation cohort. Univariate and multivariate analyses were performed to evaluate the prognostic impact on OS. A prognostic nomogram was constructed and evaluated by C-index, calibration curve, decision curve analysis (DCA), and risk stratification system.

Results
Ultimately, 6809 and 2918 patients diagnosed with metastatic LUAD in the training and validation cohorts were enrolled in the study, respectively. A male sex, a later T and N stage, a larger tumor size, treatment including no surgery, no chemotherapy and no radiotherapy, metastasis sites were found to be independent risk factors in LUAD patients for worse OS, and then incorporated into the nomogram. The frequency of bone metastasis was the highest, and in single site metastasis, the prognosis of liver metastasis was the worst. Two-site metastasis is more common than three-site and four-site metastasis, and co-metastasis eventually leads to a worse survival outcome. The C-index value of nomogram for predicting OS were 0.798, 0.703 and 0.698 in the internal training, validation and external validation cohorts, separately. The calibration curves for the 6-months, 1-year and 2-year showed significant agreement between nomogram models and actual observations. The DCA curves indicated nomogram was more beneficial than the AJCC TNM stage. Patients were further divided into low-risk and high-risk groups according to nomogram predicted scores and developed a survival risk classification system.

Conclusions
Our prognostic nomogram is expected to be an accurate and individualized clinical predictive tool for predicting OS in LUAD patients with different patterns of metastasis.