bluuebunny/crossref_metadata_2025_split huggingface dataset:
Positive and Negative Predictors of Mental Health in College Students. A cross-sectional predictive study
Authors: Nogueira Maria José Carvalho Carvalho 
Published: February 2023

Abstract
BACKGROUND
Academic life exposes college students to multiple adjustments, demands, and vulnerabilities that can cause stress and mental health problems. Recognizing positive or negative predictors of students' mental health promotes personal development, well-being, and academic success. To identify psychological well-being and psychological distress predictors in college students' mental health.
METHODS
This cross-sectional predictive study design used a non-probabilistic 560-sample of students; 446 were women. Participants' age ranged from 18 to 41 years (x ̅ = 19.6; SD = 1.68). An online self-report questionnaire covered all variables (demographic and relational; academic; health behaviours) and measures: Mental Health Inventory; Satisfaction with Social Support Scale; Satisfaction with Academic Life Scale; and Psychological Vulnerability Scale. R
ESULTS:
Regression analyses indicate that the male students, dating, good academic performance, exercise, sleeping seven hours, satisfaction with social support, and academic life satisfaction are significant predictors (p < .05) of psychological well-being, the last two with great weight. Females, low-income, aged 21–24 years, sleeping less than 6 hours, moderate psychological vulnerability, and perception of vulnerability are significant (p < .05) negative predictors of psychological distress.
CONCLUSIONS
This study addresses positive and negative predictors of psychological well-being and distress in college students. Specific mental health promotion and morbidity prevention programs could improve students' mental health literacy and resilience.
Prediction of 5-year overall survival of tongue cancer based machine learning
Authors: Li Liangbo , Pu Cheng , Hu Yanchun , Cascone Piero , Tao Ye , Zhang Haizhong , Jin Nenghao , Zhu Liang 
Published: February 2023

Abstract
Objective
We aimed to develop a 5-year overall survival prediction model for patients with oral tongue squamous cell carcinoma based on machine learning methods.
Subjects and Methods:
The data were obtained from electronic medical records of 224 OTSCC patients at the PLA General Hospital. A five-year overall survival prediction model was constructed using logistic regression, Support Vector Machines, Decision Tree, Random Forest, Extreme Gradient Boosting, and Light Gradient Boosting Machine. Model performance was evaluated according to the area under the curve (AUC) of the receiver operating characteristic curve. The output of the optimal model was explained using the Python package (SHapley Additive exPlanations, SHAP).
Results
After passing through the grid search and secondary modeling, the Light Gradient Boosting Machine was the best prediction model (AUC = 0.860). As explained by SHapley Additive exPlanations, N-stage, age, systemic inflammation response index, positive lymph nodes, plasma fibrinogen, lymphocyte-to-monocyte ratio, neutrophil percentage, and T-stage could perform a 5-year overall survival prediction for OTSCC. The 5-year survival rate was 42%.
Conclusion
The Light Gradient Boosting Machine prediction model predicted 5-year overall survival in OTSCC patients, and this predictive tool has potential prognostic implications for patients with OTSCC.
A meta-analysis of the criterion-related validity of Session-RPE scales in adolescent athletes
Authors: Liu Haochong , Yang Wenpu , Liu Haoyang , Bao Dapeng , Cui Yixiong , Ho Indy Man Kit , Li Qian 
Published: February 2023

Abstract
Background: The objective of this study was to establish the criterion-related validity of the session-rating of perceived exertion (s-RPE) method in adolescent athletes.
Methods: According to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA 2020) guidelines, a meta-analysis (PROSPERO ID: CRD42022373126) was performed using Stata 15.1 software. Eight databases using the following terms: (‘s-RPE’ OR ‘Rating Perceived Exertion session’ OR ‘RPE session’ OR ‘RPE’ OR ‘Rate of Perceived Exertion’ OR ‘Rated of Perceived Exertion’) AND (‘Adolescen*’ OR ‘Youth*’ OR ‘Teen*’) AND (‘validity’ OR ‘correlation’ OR ‘concurrent validity’) were searched up to 2022. Articles meeting the inclusion criteria were screened and adopted the “Methodological Index for Non-Randomized Studies (MINORS)” to evaluate the risk of bias.
Results: An initial 1798 studies using the s-RPE method were identified and finally, a total of 16 studies were included for further analysis. The relationship between assessment instruments CR-10 or CR-100 modified methods of s-RPE and the heart rate measures of these selected studies were calculated using correlation coefficient (r values) and Fisher’s z-score. A strong to very strong correlation between s-RPE and HR was observed (overall: r=0.74; CR-10: r=0.69; CR-100: r=0.80). CR-100 scale (Fisher’s z=1.09) was shown to have a higher criterion validity than that of the CR-10 scale (Fisher’s z=0.85).
Conclusion: Preliminary findings showed that s-RPE using either CR-10 or CR-100 scales can be used "stand-alone" for monitoring internal training load for children and adolescent athletes. Future studies should focus on whether CR-100 could better perform than CR-10 for junior and children athletes in different age groups and sports as well as the causes leading to potential scoring biases.
Modified Torkildsen shunt as a prophylactic procedure for postoperative hydrocephalus in fourth ventricular tumors
Authors: Su Yang , Richard Seidu. , Ren Yanming , Huang Bowen , Lan Zhigang , Zhang Yuekang 
Published: February 2023

Abstract
Introduction:
Surgery for fourth ventricular tumors is plagued by potential CSF blockage after the tumor removal due to a plethora of reasons. We re-invented the classic Torkildsen shunt as a treatment for postoperative hydrocephalus after fourth ventricular tumor removal by placing a catheter from the aqua duct through fourth ventricle towards the cisterna magna.
Materials and methods
We prospectively gathered the data of patients who underwent surgery of the fourth ventricle tumor between January 2019 and December 2021 at the Department of Neurosurgery in West China Hospital of Sichuan University. In all, a total of 96 selective cases were selected among 237 fourth ventricle tumor cases because of their superior tumor extension into the aqueduct. The patients were categorized into modified Torkildsen and no modified Torkildsen groups and risks factors for the development of postoperative hydrocephalus evaluated and their clinical outcomes were compared.
Result
In all 20 patients developed postoperative hydrocephalus out of the 96 patients included in the study. All the 20 patients who developed postoperative hydrocephalus were in the no modified Torkildsen group. No patient in the modified Torkildsen group developed postoperative hydrocephalus. Thus, we observed a significate statistical difference between the modified Torkildsen group and no modified Torkildsen group (p = 0.0062).
Conclusion
The modified Torkildsen shunt can be effective in preventing postoperative hydrocephalus in selected fourth tumor patients. The procedure enables one to avoid a standard ventriculoperitoneal (VP) shunt or endoscopic third ventriculostomy (ETV), especially in cases whose tumors extended superiorly and were not totally resected.
WITHDRAWN: Four weeks minimalist shoe walking improves measures of foot posture and balance in healthy young adults – a randomized controlled trial
Authors: Gabriel Anna , Wearing Scott , Horstmann Thomas , Konrad Andreas 
Published: February 2023

Abstract
Research suggests that running in minimalist shoes (MS) positively influences local and non-directly adjacent areas of the dorsal chain (DC). This study investigates the effects of 4-week MS walking in non‑runners.
28 healthy participants (15f, 13m; 25.3 ± 5.3 yrs; 70.2 ± 11.9 kg; 175.0 ± 7.8 cm) were randomly assigned to a control or intervention group. The intervention group undertook a 4‑week incremental walking program in MS, which included a daily step count of 3,000 steps/day in the first week increasing to 5,000 steps/day for the remaining 3 weeks. The control group walked in their preferred shoe (no MS). We assessed the following parameters in a laboratory at baseline [M1], and after the 4-week intervention [M2]: Foot parameters (e.g. FPI‑6), lower limb ROM, balance during single-leg stance, and muscle strength of the DC. For statistical analysis, stepwise linear regression models in forward selection were calculated.
In the MS group, the FPI-6 (b = -3.72, t(51) = -6.05, p < .001, [-4.94, 2.51]) and balance (b = -17.96, t(49) = -2.56, p = .01, [-31.54, 4.37]) significantly improved from M1 to M2, but not all other parameters (all p >.05).
Walking with MS might be an advantageous intervention for non-runners.
Evaluation of a novel lysis-based sample processing method to optimize Vibrio vulnificus detecting by Loop-Mediated Isothermal Amplification assay
Authors: Zhang Lei , Liu Jianfei , Qin Kewei , Wu Chenglin , Zhou Lijun , ma hui 
Published: February 2023

Abstract
Purpose
To explore a rapid sample preprocessing method suitable for Vibrio vulnificus detecting by Loop-Mediated Isothermal Amplification assay to shorten the total detecting time and increase efficiency.
Methods
A water-lysis sample processing method was established by optimizing the bacteria/water ratio, and V. vulnificus, the specific pathogen, was detected using the lysis-based LAMP assay established in our study. To evaluate its efficiency, pure bacteria gradient dilution and commercial products were detected for specificity and sensitivity. V. parahemolyticus, V .alginolyticus, and Proteus mirabilis were used to confirm its broad-spectrum application.
Result
The water-lysis-based V. vulnificus detecting LAMP method shortened preprocessing time to ≤1 min with 100% LAMP specificity; the detection limits of the LAMP assay were decreased to 1.2 × 102 CFU/mL in pure culture, and 1.47 × 103 CFU/g in oyster, respectively. Furthermore, the 100% LAMP specificity and high sensitivity of the water-lysis method were also obtained on detecting V. parahaemolyticus, V. alginolyticus, and P. mirabilis, revealing its excellent LAMP adaption with improvement in sensitivity and efficiency.
Conclusion
Our study provided a novel LAMP preprocessing method that was faster and more precise compared to common methods and possessed the practical potential for LAMP application in the future.
The potential of IBDV attenuated live vaccine against novel variant strain
Authors: Leng Mei , bian xiaomeng , chen yazheng , liang zhishan , lian jiamin , chen meng , chen feng , wang zhanxin , lin wencheng 
Published: February 2023

Abstract
Infectious bursal disease virus (IBDV) caused an acute and highly contagious infectious disease characterized by and severe immunosuppression, causing great economic losses to the poultry industry globally. Over the past 30 years, this disease has been well controlled based on the scientific strategy of vaccination and the strict biosafety measures. However, the novel variant IBDV strain emerged in recent years, posting a new threat to the poultry industry. Few novel variant IBDV strain was isolated from 2512-immunized chickens in our previous epidemiological survey, providing clues that the attenuated live vaccines maybe efficacious against the novel variant strains. Here, we reported the protective effect of the attenuated live vaccine (2512 strain) against novel variant strain in SPF chickens and commercial yellow-feathered broilers. We found that 2512 causes severe atrophy of the bursa of Fabricius in SPF chickens and commercial yellow-feathered broilers, that 2512 induces high levels of antibodies against IBDV, and that 2512 limits viral growth of the novel variant strains via placeholder effect. This study highlighted the protective effect of commercial attenuated live vaccines against the novel variant IBDV, and pro-vide guidance for the prevent and control of this disease.
A randomized, controlled study to evaluate the safety and immunogenicity of a heterologous booster dose of an adjuvanted SARS CoV-2 recombinant spike protein vaccine in adults
Authors: Kulkarni Prasad , Gunale Bhagwat , Kohli Sunil , Lalwani Sanjay , Tripathy Srikanth , Kar Sonali , Raut Sidram , Kulkarni Praveen , Apte Aditi , Bavdekar Ashish , Bhalla Hira Lal , Plested Joyce , Cloney-Clark Shane , Zhu MingZhu , Kalkeri Raj , Pryor Melinda , Hamilton Stephanie , Thakar Madhuri , Sannidhi Ranga , Baranwal Punjita , Bhamare Chetanraj , Dharmadhikari Abhijeet , Gupta Manish , Poonawalla Cyrus , Shaligram Umesh , Kapse Dhananjay 
Published: February 2023

Abstract

Background
Due to waning immunity following primary immunization with Covid-19 vaccines, booster doses may be required. The present study assessed a heterologous booster of SII-NVX-CoV2373 (spike protein vaccine) in adults primed with viral vector and inactivated vaccines.
Methods
In this Phase 3, observer-blind, randomized, active controlled study, a total of 372 adults primed with ChAdOx1 nCoV-19 (n = 186) or BBV152 (n = 186) at least six months ago, were randomized to receive a booster of SII-NVX-CoV2373 or control vaccine. The control group received homologous booster of ChAdOx1 nCoV-19 or BBV152 depending upon the prime cohort. Anti-S IgG and neutralizing antibodies were assessed at baseline (day 1), day 29, day 91 and day 181 for immunogenicity assessments. Solicited reactions were collected for one week after vaccination. Unsolicited adverse events (AEs) were collected for 28 days while serious adverse events (SAE) and adverse events of special interest (AESI) were reported throughout the six-month study duration. (Identifier: CTRI/2022/04/042017)
Results
In both the ChAdOx1 nCoV-19 primed group and BBV152 primed group, 186 participants each received the study vaccines. In the ChAdOx1 nCoV-19 Prime cohort, at 28 days after the booster dose, there was a 3.9- to 5.1-fold-rise and 1.9- to 2.8-fold-rise in anti-S IgG and neutralizing antibody titres from the baseline in the SII-NVX-CoV2373 group and the ChAdOx1 nCoV-19 group, respectively. The same responses for the BBV152 prime cohort was 7.4- to 10.4-fold-rise and 1.5- to 2.5-fold-rise in the SII-NVX-CoV2373 group and the BBV152 group, respectively. There was 86.96% (95% CI 78.32, 93.07) to 94.57% (95% CI 87.77, 98.21) and 37.63% (95% CI 27.79, 48.28) to 79.57% (95% CI 69.95, 87.23) anti-S IgG and neutralizing antibody seroresponse (2-fold-rise from baseline) in the SII-NVX-CoV2373 group and ChAdOx1 nCoV-19 group, respectively. The same was 94.51% (95% CI 87.64, 98.19) to 98.90% (95% CI 94.03, 99.97) and 20.43% (95% CI 12.77, 30.05) to 74.19% (95% CI 64.08, 82.71) in the SII-NVX-CoV2373 group and BBV152 group, respectively. No SAE or AESI was caused by the study vaccines.
Conclusion
SII-NVX-CoV2373 showed a numerically higher boosting effect than homologous boosters in adults primed with ChAdOx1 nCoV-19 and BBV152. The vaccine was also safe and well tolerated.
Effect of enforcement of referral guidelines on patterns of orthopedic and trauma admissions to Kenyatta National Hospital, Kenya: quasi- experimental study design
Authors: Omondi Maxwell Philip , Mwangi Joseph Chege , Sitati Fred Chuma , Onga’ngo Herbert 
Published: February 2023

Abstract
Inappropriate utilization of higher-level health facilities and ineffective management of referral processes in resource-limited settings is increasingly becoming a concern in health care management in developing countries. This is characterized by self-referral and frequent bypassing of the nearest health facilities coupled with low formal referral mechanisms. This scenario lends itself to a situation where uncomplicated medical conditions are unnecessarily managed in a high-cost health facility. On July 1, 2021, Kenyatta National Hospital (KNH) did enforce the referral guidelines that required patients have a formal referral letter to KNH to reduce the number of walk-ins and allow KNH to function as a referral facility as envisioned by Kenya 201 constitution and KNH legal statue of 1987.
Study Objective: To determine the effect of referral guidelines on patterns of orthopaedic and trauma admissions to KNH.
Methodology: This was a quasi – experimental design. Data abstraction was done for 459 and 446 before and after enforcement of referral guidelines.
Findings enforcement of the referral guidelines reduced the proportion of walk-in admissions from 54.9% to 45.1%, while facility referrals increased from 46.6% to 53.4%. The Non-trauma orthopaedic admissions doubled from 12.0% to 22.4% after enforcement of the referral guidelines (p<0.001). The mean age was 33.8 years with mean age rising among females from 32.2 years to 38.0 years after the enforcement of the referral guidelines. There was a significant increase in the proportion of female admissions after the enforcement of the referral guidelines. The enforcement of the referral guidelines was associated with a statistically significant increase in the number of orthopaedic admissions with active insurance cover.
Conclusion: the enforcement of the referral guidelines reduced the proportion of walk-ins. The enforcement of the guidelines was also associated with orthopaedic and trauma admissions with more non-trauma cases, tertiary education level, and more active insurance cover.
Utility of a rapid assay for Prostaglandin E-major urinary metabolite as a biomarker in pediatric ulcerative colitis
Authors: Hagiwara Shin-ichiro , Abe Naoki , Hosoi Kenji , Hara Tomoko , Ishige Takashi , Shimizu Hirotaka , Mizuochi Tatsuki , Kakiuchi Toshihiko , Kunisaki Reiko , Matsuoka Ryo , Kondou Hiroki , Kakuta Fumihiko , Nakayama Yoshiko , Kimura Takeshi , Honma Hitoshi , Hirano Daishi , Saruta Masayuki , Yoshida Tsutomu , Okayasu Isao , Etani Yuri , Maeyama Takatoshi 
Published: February 2023

Abstract
Prostaglandin E-major urinary metabolite (PGE-MUM) is a urinary biomarker reflecting ulcerative colitis (UC) activity. This prospective observational study aimed to evaluate the usefulness of PGE-MUM via rapid chemiluminescent enzyme immunoassay in detecting endoscopic remission (ER) and histologic remission (HR) in pediatric UC (6–16 years) in comparison with fecal calprotectin (FCP). ER and HR were defined as Mayo endoscopic score (MES) of 0 and Matts’ histological grades (Matts) of 1 or 2, respectively. A total of 104 UC and 39 functional gastrointestinal disorder (FGID) were analyzed. PGE-MUM levels were significantly higher in the UC group than in the FGID group (P < 0.001). FCP levels were significantly elevated in the group without ER and HR than in the group with ER and HR (P < 0.001 and P = 0.001), whereas PGE-MUM levels were significantly higher in the group without ER compared to the group with ER (P < 0.001). No significant differences were noted in the AUCs for PGE-MUM and FCP in detecting ER and HR. Although PGE-MUM was inferior to FCP for the detection of HR, it might have the potential for application as a biomarker of endoscopic activity in pediatric UC owing to its noninvasive and rapid method.
Utility of robotic surgery for Siewert type II/III adenocarcinoma of esophagogastric junction: transhiatal robotic versus laparoscopic approach
Authors: Nishi Masaaki , Wada Yuma , Yoshikawa Kozo , Takasu Chie , Tokunaga Takuya , Nakao Toshihiro , Kashihara Hideya , Yoshimoto Toshiaki , Shimada Mitsuo 
Published: February 2023

Abstract
Background
Robotic surgery (RS) has been rapidly adopted for gastric cancer and adenocarcinoma of the esophagogastric junction (AEG). However, the utility of RS for Siewert type II/III AEG remains unclear.
Methods
Forty-one patients who underwent either transhiatal RS (n = 15) or laparoscopic surgery (LS) (n = 26) for Siewert type II/III AEG were enrolled in this study. The surgical outcomes of the two groups were compared.
Results
In the entire cohort, there were no significant intergroup differences in the operative time, blood loss volume, or number of retrieved lymph nodes. The length of the postoperative hospital stay was shorter in the RS group than in the LS group (14.20 ± 7.10 days vs. 18.73 ± 17.82 days, respectively; p = 0.0388). The morbidity rate (Clavien–Dindo grade ≥ 2) was similar between the groups. In the Siewert II cohort, there were no significant intergroup differences in short-term outcomes. In the entire cohort, there was no significant difference between the RS and LS groups in the 3-year overall survival rate (91.67% vs. 91.48%, N.S.) or 3-year disease-free survival rate (91.67% vs. 91.78%, N.S.), respectively. Likewise, in the Siewert type II cohort, there was no significant difference between the RS and LS groups in the 3-year overall survival rate (80.00% vs. 93.33%, N.S.) or 3-year disease-free survival rate (80.00% vs. 94.12%, N.S.), respectively.
Conclusions
Transhiatal RS for Siewert II/III AEG was safe and contributed to similar short-term and long-term outcomes compared with LS.
DSMP-CNN: Dual Spin Max Pooling Convolutional Neural Network for Solar Cell Crack Detection
Authors: Hassan Sharmarke , Dhimish Mahmoud 
Published: February 2023

Abstract
This paper presents a solar cell crack detection system for use in photovoltaic (PV) assembly units. The system utilizes four different Convolutional Neural Network (CNN) architectures with varying validation accuracy to detect cracks, microcracks, Potential Induced Degradations (PIDs), and shaded areas. The system examines the electroluminescence (EL) image of a solar cell and determines its acceptance or rejection status based on the presence and size of the crack. The proposed system was tested on various solar cells and achieved a high degree of accuracy, with an acceptance rate of up to 99.5%. The system was validated with thermal testing using real-world cases, such as shaded areas and microcracks, which were accurately predicted by the system. The results show that the proposed system is a valuable tool for evaluating the condition of PV cells and can lead to improved efficiency. The study also shows that the proposed CNN model outperforms previous studies and can have significant implications for the PV industry by reducing the number of defective cells and improving the overall efficiency of PV assembly units.