bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enabling red thermally activated delayed fluorescence by increasing the push–pull strength in naphthalimide-phenothiazine derivatives
Authors: Montanari Chiara , Bianconi Tommaso , Sheokand Manju , Teunens Titouan , Cavalletti Giulia , Cornil Jérôme , Misra Rajneesh , Carlotti Benedetta 
Published: June 2023

The stronger push–pull character of the phenothiazine relative to the phenothiazine-dioxide derivatives is crucial to achieve negligible S1–T1 energy gap and enable reverse intersystem crossing followed by red Thermally Activated Delayed Fluorescence.
Dynamic Temporal and Tactile Cueing: Quantifying Speech Motor Changes and Individual Factors That Contribute to Treatment Gains in Childhood Apraxia of Speech
Authors: Grigos Maria I. , Case Julie , Lu Ying , Lyu Zhuojun 
Published: June 2023

Purpose:
Speech motor skill is refined over the course of practice, which is commonly reflected by increased accuracy and consistency. This research examined the relationship between auditory-perceptual ratings of word accuracy and measures of speech motor timing and variability at pre- and posttreatment in children with childhood apraxia of speech (CAS). Furthermore, the degree to which individual patterns of baseline probe word accuracy, receptive language, and cognition predicted response to treatment was explored.

Method:
Probe data were collected from seven children with CAS (aged 2;5–5;0 [years;months]) who received 6 weeks of Dynamic Temporal and Tactile Cueing (DTTC) treatment. Using a multidimensional approach to measuring speech performance, auditory-perceptual (whole-word accuracy), acoustic (whole-word duration), and kinematic (jaw movement variability) analyses were conducted on probe words produced pre- and posttreatment. Standardized tests of receptive language and cognition were administered pretreatment.

Results:
There was a negative relationship between auditory-perceptual measures of word accuracy and movement variability. Higher word accuracy was associated with lower jaw movement variability following intervention. There was a strong relationship between word accuracy and word duration at baseline, which became less robust posttreatment. Furthermore, baseline word accuracy was the only child-specific factor to predict response to DTTC treatment.

Conclusions:
Following a period of motor-based intervention, children with CAS appeared to refine speech motor control in conjunction with improvements in word accuracy. Those who demonstrated the poorest performance at treatment onset displayed the greatest degree of gains. Taken together, these results reflect a system-wide change following motor-based intervention.
The Influence of Feminist Movements on the Change of Female Images in Film and Television Dramas: Based on the Theory of Semiotics
Authors: Zhou Yuhan , Yang Fan , Yang Jialin , Wang Huiying 
Published: June 2023

Semiotics mainly studies the role of symbols in signals, language, culture, human behavior, and social mechanisms. Based on the semiotic theory of female images, this article explores the relationship between feminist ideas and female appearance, behavior, and self-choice in film and television dramas, the reasons for the prevalence of feminism, and the reasons why feminism influences female images in film and television dramas.
Semiotics, a branch of linguistics, explores how signs and symbols convey meaning in various cultural and social contexts. It studies the use of signs and symbols to represent and communicate ideas, concepts, and values. The study of semiotics has been applied to various fields, including literature, art, and media, to analyze the meaning and function of symbols and their influence on social behavior and cultural norms.
In the context of feminist theory, semiotics has been used to analyze female images in various media, including film and television dramas. Feminist scholars argue that female images in the media are often constructed through symbolic representations, which reflect and reinforce gender stereotypes and patriarchal norms. Through the use of symbols, such as clothing, makeup, and body language, female characters in film and television dramas are often portrayed in ways that emphasize their femininity, beauty, and submissiveness.
The Relationship between Western Ontario and McMaster Universities Osteoarthritis Index Score and Satisfaction after Total Knee Arthroplasty Changes Over Time
Authors: Choi Yun Seong , Chang Moon Jong , Shin Young Bin , Kim Tae Woo , Chang Chong Bum , Kang Seung-Baik 
Published: June 2023

AbstractThis study aimed to determine whether there was a relationship between preoperative patient-reported outcome measures (PROMs) and satisfaction after total knee arthroplasty (TKA), and whether there was a relationship between the amount of improvement in PROM or final PROM and satisfaction and whether that relationship differed 1 and 2 years after TKA. The Western Ontario and McMaster University Osteoarthritis Index (WOMAC) and satisfaction of 267 limbs who underwent TKA were analyzed. Logistic regression analysis was performed to determine whether there was a relationship between preoperative WOMAC or improvement in WOMAC or final WOMAC and satisfaction at 1 and 2 years after TKA. Pearson and Filon's z test was performed to determine whether there was a difference in evaluating satisfaction between the amount of improvement in WOMAC and final WOMAC. There was no significant relationship between preoperative WOMAC and satisfaction. A higher improvement in WOMAC total score and better final WOMAC total scores at 1 and 2 years after TKA were related to greater satisfaction. At 1 year after TKA, there was no significant difference in evaluating satisfaction between the amount of improvement in WOMAC and final WOMAC. However, 2 years after TKA, the final WOMAC function and total score were more related to satisfaction than the amount of improvement in WOMAC function and total score. In the early postoperative period, there was no difference in evaluating satisfaction between the amount of improvement in WOMAC and final WOMAC, whereas over time, the final WOMAC was more related to satisfaction.
Transaxillary Capsulorrhaphy with Reimplantation to Correct Bottoming-Out Deformity in Breast Mycobacterial Periprosthetic Infection: A Case Report with Literature Review
Authors: Huang Tsung-Chun , Lee Jian-Jr , Yang Kuo-Hui , Chou Chia-Huei , Chang Yu-Chen 
Published: June 2023

AbstractAugmentation mammoplasty is one of the most popular cosmetic surgeries, but there is a high reoperation rate (29.7%) commonly due to capsular contracture, implant malpositioning, infection, and unsatisfactory size. Although infection only accounts for 2% of cases, its management is very challenging, especially with nontuberculous mycobacteria (NTM) infection. Breast prosthetic NTM infection is a rare but is a disastrous condition with an incidence of approximately 0.013%. Immediate salvage reimplantation is usually not suggested, and most studies recommend a gap of 3 to 6 months after combination antibiotics therapy before reimplantation. However, delayed reimplantation often leads to great psychological stress and struggle between the doctor and patient. We present the case report of successful reimplantation in treating prosthetic NTM infections in a 28-year-old female. We discuss a novel technique “transaxillary capsulorrhaphy” to correct the bottoming-out deformity. One year after the combination of antibiotics and surgery, the follow-up computed tomography scan showed complete remission of NTM without recurrence. We discuss the surgical technique in detail. The 1-year follow-up assessment (photos and dynamic video) revealed good cosmesis and reliable correction using the new technique. This report is the first formal description and discussion of one-stage reimplantation following NTM infections. Transaxillary capsulorrhaphy allows for a successful salvage operation when an implant is displaced. This approach provides highly favorable result in eastern women undergoing revision augmentation mammoplasty. This study reflects level of evidence V, considering opinions of respected authorities based on clinical experience, descriptive studies, or reports of expert committees.
Recent Advances in the Asymmetric Doyle–Kirmse Reaction
Authors: Teng Ming-Yu , Ye Long-Wu , Shi Chong-Yang , Zhou Bo 
Published: June 2023

AbstractThe asymmetric Doyle–Kirmse reaction has become increasingly important in the construction of chiral sulfides, especially for those with quaternary carbon stereocenters. Over the few past decades, a series of catalytic asymmetric approaches have been developed promoted by copper, rhodium, nickel, and other chiral catalysts. Apart from the frequently investigated sulfonium ylides, the enantioselective [2,3]-sigmatropic rearrangement of selenium ylides and iodonium ylides has also been discovered recently. This review summarizes recent advances in the asymmetric Doyle–Kirmse reaction according to the patterns of chirality induction. The synthetic methods for rearranged products, reaction mechanisms and applications are discussed in this review.1	Introduction2	Asymmetric Doyle–Kirmse Reaction Controlled by Chiral Free Ylides3	Asymmetric Doyle–Kirmse Reaction Controlled by Chiral Metal-Bound Ylides4	Conclusion and Outlook
Synthesis of Naturally Racemic Marilines B & C through Multicomponent Reactions Involving ortho-Quinone Methides and Various Nitrogen Nucleophiles
Authors: Pettus Thomas R. R. , Wong Yuk Fai 
Published: June 2023

AbstractHerein, we report the first total synthesis of (±)-marilines B and C, as well as a failed approach to (±)-mariline A, by using our recently developed multicomponent reaction method, which involves the interception of ortho-quinone methides with various nitrogen nucleophiles to allow easy assembly of various benzylic amine cores with diverse substituents.
Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios and prognosis after aneurysmal subarachnoid hemorrhage: a cohort study
Authors: Oliveira Adilson Jose Manuel de , Rabelo Nicollas Nunes , Telles João Paulo Mota , Solla Davi Jorge Fontoura , Coelho Antonio Carlos Samaia da Silva , Barbosa Guilherme Bitencourt , Barbato Natália Camargo , Yoshikawa Marcia Harumy , Teixeira Manoel Jacobsen , Figueiredo Eberval Gadelha 
Published: June 2023

Abstract
Background Subarachnoid hemorrhage (SAH) prognosis remains poor. Vasospasm mechanism might be associated with inflammation. Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) have been studied as inflammation markers and prognostic predictors.
Objective We aimed to investigate NLR and PLR in admission as predictors of angiographic vasospasm and functional outcome at 6 months.
Methods This cohort study included consecutive aneurysmal SAH patients admitted to a tertiary center. Complete blood count was recorded at admission before treatment. White blood cell count, neutrophil count, lymphocyte count, platelet count, NLR, and PLR were collected as independent variables. Vasospasm occurrence-modified Rankin scale (mRS), Glasgow outcome scale (GOS), and Hunt-Hess score at admission and at 6 months were recorded as dependent variables. Multivariable logistic regression models were used to adjust for potential confounding and to assess the independent prognostic value of NLR and PLR at admission.
Results A total of 74.1% of the patients were female, with mean age of 55.6 ± 12.4 years. At admission, the median Hunt-Hess score was 2 (interquartile range [IQR] 1), and the median mFisher was 3 (IQR 1). Microsurgical clipping was the treatment for 66.2% of the patients. Angiographic vasospasm incidence was 16.5%. At 6 months, the median GOS was 4 (IQR 0.75), and the median mRS was 3 (IQR 1.5). Twenty-one patients (15.1%) died. Neutrophil-to-lymphocyte ratio and PLR levels did not differ between favorable and unfavorable (mRS > 2 or GOS < 4) functional outcomes. No variables were significantly associated with angiographic vasospasm.
Conclusion Admission NLR and PLR presented no value for prediction of functional outcome or angiographic vasospasm risk. Further research is needed in this field.
Associations between cognitive impairment and computed tomography perfusion in different lobes in acute stroke of the anterior circulation
Authors: Chu Mengna , Dong Bin , Huang Chao 
Published: June 2023

Abstract
Background Cognitive impairment (CI) during the acute phase of stroke should not be ignored. The present study analyzed the relationship between computed tomography perfusion (CTP) in different lobes and CI during the acute phase of stroke in patients with cerebral infarction.
Methods The present study included 125 subjects: 96 in the acute phase of stroke and 29 elderly healthy subjects as a control group. The Montreal Cognitive Assessment (MoCA) was used to evaluate the cognitive status of the two groups. The CTP scans include four parameters: cerebral blood flow (CBF), cerebral blood volume (CBV), time to peak (TTP), and mean transit time (MTT).
Results The MoCA scores for naming, language and delayed recall significantly decreased only in patients with left cerebral infarctions. The MTT of the left vessels in the occipital lobe and the CBF of the right vessels in the frontal lobe were negatively related to the MoCA scores of patients with left infarction. The CBV of the left vessels in the frontal lobe and the CBF of left vessels in the parietal lobe were positively linked to the MoCA scores of patients with left infarction. The CBF of the right vessels in the temporal lobe was positively related to the MoCA scores of patients with right infarction. Finally, the CBF of the left vessels in the temporal lobe was inversely correlated with the MoCA scores of patients with right infarctions.
Conclusion During the acute phase of stroke, CTP was closely associated with CI. Changed CTP could be a potential neuroimaging biomarker to predict CI during the acute phase of stroke.
Treating Senile Chronic Insomnia with Spirit-Calming and Blood-Nourishing Decoction Combined with Guasha (Scraping) and Acupuncture
Authors: Fu Huiya , Huang Yinfeng , Wang Zhen , Gao Xiyan 
Published: June 2023

Abstract
Objective To observe the efficacy of treating senile chronic insomnia with spirit-calming and blood-nourishing decoction combined with Guasha (scraping) and acupuncture therapy.
Methods Seventy elderly patients with chronic insomnia were included and numbered by their visiting sequence. They were randomly divided into the control group and the observation group, 35 patients for each. Spirit-calming and blood-nourishing decoction was given to the control group, whereas Guasha (scraping) and acupuncture were applied together with the spirit-calming and blood-nourishing decoction to the observation group. Both groups were treated for 4 weeks before comparing their Pittsburgh Sleep Quality Index (PSQI) score and clinic efficacy.
Results PSQI scores of both groups were significantly lowered. Compared with the control group, the differences are statistically significant (p < 0.01). After treatment, the PSQI score of the observation group is (6.80 ± 1.37), whereas that of the control group is (10.83 ± 2.51). PSQI score of the observation group is lower (p < 0.01). The effective rate was 85.7% in the observation group and 62.9% in the control group. Difference of the effective rates of both groups is statistically significant (p < 0.01).
Conclusion Spirit-calming and blood-nourishing decoction combined with Guasha (scraping) and acupuncture is significantly effective in treating senile chronic insomnia. The combined therapy can effectively relieve the symptoms.
Persistent Bacterial Vaginosis and Risk for Spontaneous Preterm Birth
Authors: Blumenfeld Yair J. , Marić Ivana , Stevenson David K. , Gibbs Ronald S. , Shaw Gary M. 
Published: June 2023

Objective The aim of this study was to determine the association between persistent bacterial vaginosis (BV) in pregnancy and risk for spontaneous preterm birth (sPTB).
Study Design Retrospective data from IBM MarketScan Commercial Database were analyzed. Women aged between 12 and 55 years with singleton gestations were included and linked to an outpatient medications database and medications prescribed during the pregnancy were analyzed. BV in pregnancy was determined based on both a diagnosis of BV and treatment with metronidazole and/or clindamycin, and persistent treatment of BV was defined as BV in more than one trimester or BV requiring more than one antibiotic prescription. Odds ratios were calculated comparing sPTB frequencies in those with BV, or persistent BV, to women without BV in pregnancy. Survival analysis using Kaplan–Meier curves for the gestational age at delivery was also performed.
Results Among a cohort of 2,538,606 women, 216,611 had an associated International Classification of Diseases, 9th Revision or 10th Revision code for diagnosis of BV alone, and 63,817 had both a diagnosis of BV and were treated with metronidazole and/or clindamycin. Overall, the frequency of sPTB among women treated with BV was 7.5% compared with 5.7% for women without BV who did not receive antibiotics. Relative to those without BV in pregnancy, odds ratios for sPTB were highest in those treated for BV in both the first and second trimester (1.66 [95% confidence interval [CI]: 1.52, 1.81]) or those with three or more prescriptions in pregnancy (1.48 [95% CI: 1.35, 1.63].
Conclusion Persistent BV may have a higher risk for sPTB than a single episode of BV in pregnancy.
Key Points
Neurodevelopmental Outcomes of a Cohort of Children with Tuberous Sclerosis Complex with Epileptic Spasms
Authors: Saini Lokesh , Mukherjee Swetlana , Gunasekaran Pradeep Kumar , Malhi Prahbhjot , Saini Arushi Gahlot , Sharma Rajni , Sharawat Indar Kumar , Suthar Renu , Sahu Jitendra Kumar , Sankhyan Naveen 
Published: June 2023

AbstractThe neurodevelopmental outcomes in children with tuberous sclerosis complex (TSC) with epileptic spasms remain underdiagnosed and might be responsible for significant morbidity and mortality burdens, even after spasms abate. The study was a cross-sectional study over 18 months at a tertiary care pediatric hospital, involving 30 children with TSC who had epileptic spasms. They were assessed with Diagnostic and Statistical Manual of Mental Disorders-5 criteria for autism spectrum disorder (ASD), attention deficit hyperactivity disorder (ADHD), and intellectual disability (ID), and childhood psychopathology measurement schedule (CPMS) for behavioral disorders. The median age at onset of epileptic spasms was 6.5 (1–12) months, and the age at enrolment was 5 (1–15) years. Of 30 children, 2 (6.7%) had only ADHD, 15 (50%) had only ID/GDD (global developmental delay), 4 (13.3%) had ASD and ID/GDD, 3 (10%) had ADHD and ID/GDD, and 6 (20%) had none. The median intelligence quotient/development quotient (IQ/DQ) score was 60.5 (20–105). CPMS assessment revealed significant behavioral abnormalities in almost half the children. Eight (26.7%) patients were completely seizure-free for at least 2 years, 8 (26.7%) had generalized tonic-clonic seizures, 11 (36.6%) had focal epilepsy, and 3 (10%) had evolved into Lennox-Gastaut syndrome. A high proportion of neurodevelopment disorders, including ASD, ADHD, ID/GDD, and behavioral disorders were seen in this pilot study with a small cohort of children with TSC with epileptic spasms.
AI technology application and employee responsibility
Authors: Wang Jing , Xing Zeyu , Zhang Rui 
Published: June 2023

AbstractEmployees are important stakeholders of firms, and employee responsibility is a crucial dimension of corporate social responsibility. This study employed a multivariable linear regression model to analyze the impact of AI technology on the variation in employee responsibility. We also utilized multiple methods, such as propensity score matching and alternative indicator analysis, to ensure the robustness of the research results. We theorized and found that the application of AI technology has a negative effect on employee responsibility, with supervision cost partially mediating the relationship between AI technology application and employee responsibility. Moreover, the negative relationship between AI technology application and employee responsibility decreases as the level of product market competition in which the firm operates increases, and it is stronger in government-controlled firms than in privately controlled firms. We also found that AI technology application and employee responsibility can improve firm productivity, and employee responsibility has a significant positive impact on innovation output and innovation efficiency, while the application of AI technology does not significantly impact innovation output and innovation efficiency. Our study contributes to research on the impact of AI technology in the workplace and has important implications for organizational practices regarding the application of AI technology and employee responsibility.
Manipulating omega-3 and omega-6 fatty acids in sheep: depletion of long-chain omega-3 polyunsaturated fatty acids by feeding different grain types
Authors: Taylor R. D. , Clayton E. H. 
Published: June 2023

Context Plasma fatty acid profiles provide evidence of short-term feeding, while red blood cells (RBC) indicate longer-term feeding effects. Information on the rate of change in fatty acid profiles of sheep blood over time after alterations in diet is lacking. This study monitored the short- and longer-term effects of feeding grain-based diets to lambs on changes to omega-3 polyunsaturated fatty acids (PUFA) in blood fractions over 21 days. The data provide a guide to managing omega-3 PUFA availability for adequate tissue accretion of these fatty acids. Aims To determine the rate of depletion over 21 days of omega-3 PUFA in the blood fractions of sheep fed on grain-based diets. Methods Blood samples were taken from ewes taken off pasture and fed grain-based diets for 21 days. Fatty acid profiles in the blood plasma and RBC were used to monitor the rate of depletion of omega-3 PUFA. Key results Immediate changes in plasma omega-3 PUFA concentrations occurred from the first day of grain feeding. The omega-3 PUFA content declined continuously on all five grains, but with substantial differences among them. RBC omega-3 PUFA contents displayed great variation across individual sheep but depletion was not significant. Conclusions Plasma omega-3 PUFA depletion immediately on grain feeding indicated a lower availability for tissue accretion in growing sheep following short-term changes in diet. The lack of change in RBC omega-3 PUFA concentrations over 21 days indicated a differential accumulation of these fatty acids in this lipid depot compared with plasma, and changes in other tissues should also be examined. Implications The effect of these short- and long-term changes on LCn-3PUFA accumulation in meat and reproductive tissues warrants further investigation.