bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Signaling Effect of Biophilic Job Posts: Do Applicants Trade Green for Green?
Authors: Merriman Kimberly K. , Kostanski Sarah A. , Ebrahimi Nabi , Montag‐Smit Tamara A. 
Published: January 2025

ABSTRACTContemporary job postings increasingly rely on visual content to attract applicants through social media platforms, calling for scholarly attention to organizational aesthetics in recruitment. This study accordingly examines the signaling function of biophilic workspace design conveyed in job posts. We integrate theorizing on organizational aesthetics and biophilia with signaling theory to posit that biophilic job posts serve a dual signaling role as both a stimulus of signal attention by eliciting a visceral response and as a signaled source of credible information by evoking an evolutionary disposed cognitive interpretation. More specifically, we model pleasure and arousal as an indicator of stimulated attention, organizational attraction and the willingness to trade pay as evaluated responses to the signal, and attributions of communal organizational traits as an intervening interpretation of the signal—consistent with the role of symbolic attributes in prospective applicant evaluation of organizations. Three primary experiments largely support our predictions. Overall, this research extends the function of aesthetic signals to organizational signaling, validates organizational aesthetics as a stimulus of directed evaluation, and expands the scope of biophilic theory in organizational research. Findings also inform the practical question of whether biophilic job posts function as a non‐pecuniary differentiator in recruitment.
US Monetary Policy and Indeterminacy
Authors: Nicolò Giovanni 
Published: January 2025

ABSTRACTIn this paper, I investigate the stance of the US monetary policy in the postwar period. To this end, I show that two features are key: a rich structural model and a parameterization of the indeterminate solution that ensures a sufficient exploration of the indeterminacy region during the estimation procedure. Therefore, I estimate a medium‐scale model on the US macroeconomic data using a novel solution method to allow for indeterminacy. The evidence of a passive monetary policy in the pre‐1979 period is pervasive and robust to the use of alternative model specifications and data. By contrast, the evidence of an active stance after 1979 is overturned if the period of the Volcker disinflation is excluded or if the model is estimated including a time‐varying inflation target and data on inflation expectations.
Influence of Seven Ion Species on Osteogenic Differentiation of Mesenchymal Stem Cells Stimulated by Macrophages in Indirect and Direct Coculture Systems
Authors: Obata Akiko , Iguchi Makito , Yasue Hikaru , Kasuga Toshihiro 
Published: January 2025

ABSTRACTImplanted biomaterials release inorganic ions that trigger inflammatory responses, which recruit immune cells whose biochemical signals affect bone tissue regeneration. In this study, we evaluated how mouse macrophages (RAW264, RAW) and mesenchymal stem cells (KUSA‐A1, MSCs) respond to seven types of ions (silicon, calcium, magnesium, zinc, strontium, copper, and cobalt) that reportedly stimulate cells related to bone formation. The collagen synthesis, alkaline phosphatase activity, and osteocalcin production of the MSCs varied by ion dose and type after culture in the secretome of RAW cells. However, DNA production was relatively unaffected. The MSC secretome may also stimulate RAW cells in coculture and, therefore, affect osteogenic differentiation of MSCs. Overall, the ions often exerted different effects on each cell type. This study guides future work that explores the mechanisms behind ion‐dependent osteogenic differentiation and cell functions.
Familial polyposis syndrome and achalasia in a young adult
Authors: Lorusso Vivas Gabriella A. , Brady Ann‐Christina , Llanos‐Chea Alejandro 
Published: January 2025

AbstractWe report the case of a 19‐year‐old White male diagnosed with familial adenomatous polyposis (FAP), Gardner's syndrome (GS) phenotype, status post total colectomy, who developed progressive dysphagia and weight loss. He was diagnosed with achalasia based on imaging and esophageal manometry. The patient underwent a Heller myotomy with the resolution of symptoms. To date, no previous literature has reported on concurrent FAP or GS and achalasia. Although FAP and achalasia are both rare conditions with no previously known concurrent occurrence, association, or described syndrome, it is important to be vigilant of this new case report finding. One must also consider the increased risk of malignancy in patients with achalasia in addition to the significant risk of malignancy in patients with FAP/GS.
African elephants influence browse availability for black rhinoceroses in Gonarezhou National Park, Zimbabwe
Authors: van der Westhuizen Marileen , Clegg Bruce , Visser Vernon , O'Connor Tim 
Published: January 2025

AbstractTranslocations are essential for the establishment of new populations of the critically endangered black rhinoceros (Diceros bicornis), but success will largely depend on forage availability. We investigated the degree of competition for woody browse between African savanna elephants (Loxodonta africana) and a recently reintroduced population of rhinoceroses in Gonarezhou National Park in Zimbabwe in the dry season of 2022. We examined overlap in space use and selection for plant species, stem diameters, and feeding height by measuring use of shrubs by both species at 75 sites across a range of topo‐edaphic conditions. Areas heavily used by rhinoceroses had high shrub densities, were close to water, and were on alkaline soils with elevated conductivity. Sites with medium to high levels of rhinoceros use were nested within areas of high elephant use. We also observed high elephant use in areas not favored by rhinoceroses, occurring farther from water and having lower shrub densities. Both species avoided thickets on acidic soils. There was substantial overlap in feeding areas, the plant species selected, and foraging height, although elephants used stems with larger diameters than rhinoceroses. Feeding by elephants on woody plants often resulted in a proliferation of small‐diameter coppice stems, which rhinoceroses used more than non‐coppice growth. Elephants did not appear to favor small coppice stems, indicating a degree of elephant‐induced facilitation of browse for rhinoceroses. Evidence for competition with elephants indicates black rhinoceroses may be best introduced into areas with a low elephant density.
Two rodent suborders have evolved missing amino acids in the lipid‐binding region of apolipoprotein E
Authors: Puppione Don L. 
Published: January 2025

AbstractThe order Rodentia comprises nearly 45% of all extant taxa, currently organized into 31 living families, some 450 genera, and roughly 2010 species (Kelt & Patton, 2020). Considering that rodents began evolving at least 66 million years ago, it is not surprising that they have diversified into five distinct suborders. With the advent of molecular biology, this difference can often be seen at the molecular level as well. Previous studies have indicated that the apolipoprotein E (APOE) of guinea pigs, belonging to the suborder Hystricomorpha, have fewer amino acids than have been reported for other suborders of Rodentia. Searching the genomic database for hystricomorph APOE genes, it was found that hystricomorphs were missing residues both in the vicinity of the hinge region and in the lipid‐binding region of the apolipoprotein. In the hinge region, missing residues varied between 5 and 3, and in the latter region, seven residues were missing. The search also revealed that castorimorphs, although lacking the smaller of the two deletions, were also missing the same seven residue deletion as found in APOE of the hystricomorphs.
Ferrofluid‐Assisted Dynamic Metasurface 3D Holography Endowed With Rapid, Linear, and High‐Contrast Color Modulation
Authors: Sun Shuo , Li Jin , Li Xiaoxun , Feng Yaoyao , Chen Liang 
Published: January 2025

AbstractMetasurface holography offers a highly promising approach for naked‐eye, full‐color, 3D displays. However, the natural static structure and material of the metasurface limit its ability to dynamically regulate the light field, posing a challenge for achieving photorealistic 3D holography. Here, a ferrofluid‐assisted dynamic metasurface is first demonstrated, conducting a 3D holography endowed with rapid, linear, and high‐contrast color modulation. The ferrofluid has nano‐structural control properties (flow behavior of nanoparticles and emulsion) that enable dynamic manipulation of the extinction (absorption and scattering) intensity in micron region across a broadband spectrum range (400–850 nm). By integrating the ferrofluid with a broadband metasurface, a novel dynamic meta‐hologram is created, which can not only regulate both amplitude and phase of the light field under a single wavelength laser but also in situ linearly changing the color of holographic images under multi‐wavelength lasers. This method provides a new perspective for implementing dynamic metasurface 3D holography capable of continuous color response.
Ginsenoside Rk2 alleviates hepatic ischemia/reperfusion injury by enhancing AKT membrane translocation and activation
Authors: Shen Hong , Fu Jiajun , Liu Jiayue , Zou Toujun , Wang Kun , Zhang Xiao‐Jing , Wan Jian‐Bo 
Published: January 2025

AbstractHepatic ischemia–reperfusion injury (IRI) poses a significant threat to clinical outcomes and graft survival during hemorrhagic shock, hepatic resection, and liver transplantation. Current pharmacological interventions for hepatic IRI are inadequate. In this study, we identified ginsenoside Rk2 (Rk2), a rare dehydroprotopanaxadiol saponin, as a promising agent against hepatic IRI through high‐throughput screening. The pharmacological effects and molecular mechanisms of Rk2 on hepatic IRI were further evaluated and elucidated in vitro and in vivo. Rk2 significantly reduced inflammation and apoptosis caused by oxygen‐glucose deprivation and reperfusion in hepatocytes and dose dependently protected against hepatic I/R‐induced liver injury in mice. Integrated approaches, including network pharmacology, molecular docking, transcriptome analysis, and isothermal titration calorimetry, along with experimental validation, indicated that Rk2 protects against hepatic IRI by targeting and activating the AKT (RAC serine/threonine protein kinase) signaling pathway. Pharmacological inhibition of AKT pathway or knockdown of AKT1 effectively diminished protective effects of Rk2. Rk2 directly binds to AKT1, facilitating its translocation from the cytoplasm to plasma membrane. This process markedly enhanced AKT interaction with PDPK1, promoting the activation of AKT1 and its downstream signaling. Our findings demonstrate that Rk2 protects against hepatic IRI by activating AKT signaling through direct binding to AKT1 and facilitating its membrane translocation.
The crosstalk between senescence, tumor, and immunity: molecular mechanism and therapeutic opportunities
Authors: Wang Zehua , Chen Chen , Ai Jiaoyu , Gao Yaping , Wang Lei , Xia Shurui , Jia Yongxu , Qin Yanru 
Published: January 2025

AbstractCellular senescence is characterized by a stable cell cycle arrest and a hypersecretory, proinflammatory phenotype in response to various stress stimuli. Traditionally, this state has been viewed as a tumor‐suppressing mechanism that prevents the proliferation of damaged cells while activating the immune response for their clearance. However, senescence is increasingly recognized as a contributing factor to tumor progression. This dual role necessitates a careful evaluation of the beneficial and detrimental aspects of senescence within the tumor microenvironment (TME). Specifically, senescent cells display a unique senescence‐associated secretory phenotype that releases a diverse array of soluble factors affecting the TME. Furthermore, the impact of senescence on tumor–immune interaction is complex and often underappreciated. Senescent immune cells create an immunosuppressive TME favoring tumor progression. In contrast, senescent tumor cells could promote a transition from immune evasion to clearance. Given these intricate dynamics, therapies targeting senescence hold promise for advancing antitumor strategies. This review aims to summarize the dual effects of senescence on tumor progression, explore its influence on tumor–immune interactions, and discuss potential therapeutic strategies, alongside challenges and future directions. Understanding how senescence regulates antitumor immunity, along with new therapeutic interventions, is essential for managing tumor cell senescence and remodeling the immune microenvironment.
Connection between oral health and chronic diseases
Authors: Fu Di , Shu Xingyue , Zhou Ge , Ji Mengzhen , Liao Ga , Zou Ling 
Published: January 2025

AbstractChronic diseases have emerged as a paramount global health burden, accounting for 74% of global mortality and causing substantial economic losses. The oral cavity serves as a critical indicator of overall health and is inextricably linked to chronic disorders. Neglecting oral health can exacerbate localized pathologies and accelerate the progression of chronic conditions, whereas effective management has the potential to reduce their incidence and mortality. Nevertheless, limited resources and lack of awareness often impede timely dental intervention, delaying optimal therapeutic measures. This review provides a comprehensive analysis of the impact of prevalent chronic diseases—such as diabetes mellitus, rheumatoid arthritis, cardiovascular disorders, and chronic respiratory diseases—on oral health, along with an exploration of how changes in oral health affect these chronic conditions through both deterioration and intervention mechanisms. Additionally, novel insights into the underlying pathophysiological mechanisms governing these relationships are presented. By synthesizing these advancements, this review aims to illuminate the complex interrelationship between oral health and chronic diseases while emphasizing the urgent need for greater collaboration between dental practitioners and general healthcare providers to improve overall health outcomes.
Not just semantics: CO2 fertilization can be a disturbance leading to worldwide forest degradation
Authors: Lapola David M. , Blanco Carolina C. , Cardeli Barbara R. , Esquivel‐Muelbert Adriane , Martinelli João V. , Quesada Carlos A. N. , Rius Bianca F. , Silva‐Junior Celso H. L. 
Published: January 2025

Societal Impact StatementThe physiological effects of increased atmospheric CO2 (CO2 fertilization) on intact forests are generally seen as a process that might buffer them against the impacts of climate change. However, CO2 fertilization can also cause adverse changes in forest conditions, such as alterations in species composition and reduced ecosystem moisture availability. Because of this, we argue that the effect of CO2 fertilization is a disturbance that leads to changes in the functioning of worldwide forests and causes low‐intensity degradation of these ecosystems. This demonstrates that even the most remote forests in the world have been altered by human action via CO2 fertilization, and the responsibility for their integrity must be shared globally.
Disparities in Clinical Outcomes Observed Within Electronic Health Record Data From a Statewide Cohort of Pulmonary Arterial Hypertension Patients
Authors: Dalton Rachel , Desai Ankit A. , Jiao Tianze , Duarte Julio D. 
Published: January 2025

ABSTRACTHealth disparities in patients with pulmonary arterial hypertension (PAH) have not been extensively reported in the United States. The aim of this project was to characterize the extent of demographic and socioeconomic disparities in clinical outcomes within a large, diverse PAH patient population. A retrospective, population‐based study of electronic health record data from the OneFlorida Data Trust was completed. Adult patients seeking care within one of the 12 OneFlorida Network partner healthcare systems with a documented diagnosis of any form of pulmonary hypertension (PH), including PAH, via ICD‐10 code were included. Social deprivation index and healthcare provider access scores were calculated from population‐based centroids derived from patient home addresses. The primary outcome was all‐cause mortality, with secondary outcomes including hospitalization, emergency department (ED) visits, and similar clinical outcomes in a combined cohort of patients with other forms PH. A total of 6379 patients were included in the PAH cohort, and 37,412 patients were included in the nonspecific PH cohort. PAH patients with the greatest social deprivation exhibited increased rates of ED visits and hospitalizations. Despite having similar rates of ED visits and hospitalizations compared to non‐Hispanics, Hispanic PAH patients had markedly lower mortality rates. Similar associations were also observed in the combined cohort of 37,412 patients with other forms of PH. In conclusion, healthcare disparities exist in PAH outcomes across both demographic and socioeconomic boundaries. Patients identifying as Hispanic appear to have decreased rates of mortality compared to other races/ethnicities.
Thermoelectric Properties of a Light Compound Fe2S2: the Role of Electron Correlation Strengthened Spin‐Orbital Coupling
Authors: Wang Xincan , Zhou Zizhen , Yang Xiaolong , Han Guang , Lu Xu , Wang Guoyu , Zhou Xiaoyuan 
Published: January 2025

AbstractSpin‐orbit coupling (SOC) induced nontrivial bandgap and complex Fermi surface has been considered to be profitable for thermoelectrics, which, however, is generally appreciable only in heavy elements, thereby detrimental to practical application. In this study, the SOC‐driven extraordinary thermoelectric performance in a light 2D material Fe₂S₂ is demonstrated via first‐principles calculations. The abnormally strong SOC, induced by electron correlation through 3d orbitals polarization, significantly renormalizes the band structures, which opens the bandgap via Fe 3d orbitals inversion, exposes the second conduction valley with weak electron‐phonon coupling, and aligns the energy of Fe 3d and S 3p orbitals with divergent momentum in valence band. Such topological band renormalization triggers improvement of both p‐ and n‐type power factors by more than 200%. Combining with the low lattice thermal conductivity caused by lone pair electrons and intense high‐order phonon scattering, the peak zT can reach 1.6 and 1.8 for p‐ and n‐type Fe₂S₂ at 400 K, respectively. This work unravels the mechanism of SOC‐provoked high zT in electron correlation systems, which inspires the development of high‐performance thermoelectric materials without heavy and scarce elements.
Recent Advances on Characterization Techniques for the Composition‐Structure‐Property Relationships of Solid Electrolyte Interphase
Authors: Lu Hongyi , Nagarathinam Mangayarkarasi , Chen Yue , Zhang Weijian , Chen Xi , Chen Jing , Tao Jianming , Li Jiaxin , Lin Yingbin , Kolosov Oleg , Huang Zhigao 
Published: January 2025

AbstractThe Solid Electrolyte Interphase (SEI) is a nanoscale thickness passivation layer that forms as a product of electrolyte decomposition through a combination of chemical and electrochemical reactions in the cell and evolves over time with charge/discharge cycling. The formation and stability of SEI directly determine the fundamental properties of the battery such as first coulombic efficiency (FCE), energy/power density, storage life, cycle life, and safety. The dynamic nature of SEI along with the presence of spatially inhomogeneous organic and inorganic components in SEI encompassing crystalline, amorphous, and polymeric nature distributed across the electrolyte to the electrolyte‐electrode interface, highlights the need for advanced in situ/operando techniques to understand the formation and structure of these materials in creating a stable interface in real‐world operating conditions. This perspective discusses the recent developments in interface‐sensitive in situ/operando techniques, providing valuable insights and addressing the challenges of understanding the composition/structure/property of SEI and their correlations during the formation processes at spatio‐temporal resolution across various length scales.
“I Am the Universe”: Toward a Reader Model That Centers Culture
Authors: Peele Roderick , Nash Kindel Turner 
Published: January 2025

ABSTRACTCulture and language shape the way people read. Yet, within many popular reading models of reading development, culture is a component, if featured at all. Illustrated through examples of pro‐Black, culturally sustaining, emancipatory practices of one teacher, this article highlights the Cultural Sustenance View of Reading, a reader model that can be used by reading teachers to center and sustain culture in children's reading development and their literacy futures.
Covert Sourcing Strategies as Activism Against Fake News
Authors: VanDonkelaar Rachael 
Published: January 2025

ABSTRACTIn the 21st century, fake news has detrimental consequences on global communities, relationships, and democracies. Unfortunately, youth unknowingly engage with misinformed content on their social media platforms. Teenagers often turn to social media for information, and it is essential that teachers address reading strategies such as sourcing to support informed reading. However, although teachers understand the benefits of sourcing, otherwise known as investigating online claims, research shows that educators do not feel confident in teaching such skills. With personal stories embedded throughout, this research‐to‐practice article provides practical strategies for teachers to gently incorporate sourcing into their classrooms.
Eosinophilic folliculitis with multifocal distribution in a dog
Authors: Ushimaru Miwa , Sekiguchi Maiko , Iwasaki Toshiroh 
Published: January 2025

AbstractA 10‐month‐old non‐neutered male beagle exhibited alopecia with scabbing and erythema on the head and lateral sides of all four limbs, alongside itching and general deterioration. Histopathological findings revealed intraepidermal or infundibular eosinophil‐dominated pustules. A diagnosis of canine eosinophilic dermatitis was established based on histopathological and clinical findings. Treatment with prednisolone (2 mg/kg, once daily) promptly improved the dermatological symptoms and general condition. The dose was gradually tapered over 3 weeks until withdrawal without recurrence. Canine eosinophilic dermatitis with intraepidermal pustules is rare and reported to be recurrent. However, the present case responded extremely well to treatment with prednisolone and did not experience recurrence, similar to eosinophilic dermatitis without intraepidermal pustules.