bluuebunny/crossref_metadata_2025_split huggingface dataset:
Faktor Keterlambatan Pekerjaan Bangunan Pelimpah pada Proyek Bendungan Jlantah Jatiyoso Karanganyar
Authors: Tri Febriantoro Deni , Priyanto Budi 
Published: March 2023

Bangunan Pelimpah adalah struktur yang digunakan untuk menyediakan aliran yang terkendali dari bendungan ke daerah hilir. Bangunan pelimpah berfungsi untuk mengalirkan air banjir yang masuk ke dalam waduk supaya tidak membahayakan keamanan tubuh bendungan. Perkembangan pembangunan yang semakin meningkat melahirkan pesatnya perkembangan perusahaan jasa yang bergerak di bidang konstruksi. Pada kenyataannya pelaksanaan proyek konstruksi selalu mengalami kendala yang mengakibatkan keterlambatan penyelesaian pekerjaan, sehingga waktu penyelesaian pekerjaan tidak sesuai dengan yang telah ditetepkan pada dokumen kontrak pekerjaan. Metode penelitian ini menggunakan metode kualitatif yaitu dengan melakukan wawancara dan studi literatur untuk mengidentifikasi faktor risiko yang menyebabkan keterlambatan pekerjaan dan pengelolaan risiko pekerjaan beton. Berdasarkan hasil penelitian terdapat beberapa penyebab keterlambatan yang telah diidentifikasi yaitu keterlambatan keterseduaan beton, faktor curah hujan, faktor kurangnya ketersediaan tenaga kerja, Faktor kurangnya kedisiplinan tenaga kerja, Faktor kurangnya keahlian tenaga kerja, Faktor komunikasi antar kontraktor dan owner.
Großes Übungsbuch Spanisch Neu
Authors: Bonachera Álvarez Trinidad , Álvarez Olañeta Pedro 
Published: March 2023

Mit dem Großen Übungsbuch Spanisch Neu können Sie – mit Vorkenntnissen auf dem Niveau A2 – alle Problemfelder von Grammatik und Sprachgebrauch anhand von 3.000 Übungssätzen ausführlich und differenziert üben. Vor jeder Übung erhalten Sie eine kurze Einführung in das jeweilige Grammatikthema. Vokabeln, die Ihnen Schwierigkeiten bereiten könnten, werden im Anschluss an die Übung mit Übersetzung aufgelistet. Ein Lösungsschlüssel befindet sich im Anhang. Darüber hinaus lädt ein Verweis auf die betreffende Stelle in der Großen Lerngrammatik Spanisch zur Vertiefung des Themas ein.
Transformation managériale : une arlésienne, vraiment ?
Authors: Arnéra David , Demaille Frank 
Published: March 2023

Les entreprises multiplient les plans de transformation toujours plus globaux et ambitieux, afin de faire évoluer leur culture et leur management. ENGIE et L’Oréal illustrent deux approches, l’une visant directement les comportements, l’autre passant par des modifications de périmètres, une harmonisation des outils, ou encore un changement d’organisation. Dans les deux cas, le grand enjeu est le même : au-delà de l’affirmation d’une vision et de principes, comment distiller la transformation jusque dans les pratiques quotidiennes ?
Anticipations rationnelles : équivalence observationnelle et déstabilisation
Authors: Chatelain Jean-Bernard , Ralf Kirsten 
Published: March 2023

Cet article pointe deux inconvénients concernant l’usage actuel des anticipations rationnelles dans les modèles nouveaux keynésiens d’équilibre général dynamique et stochastique. Le premier inconvénient est que pour un modèle à anticipations rationnelles avec des chocs autorégressifs inobservables, on peut toujours trouver un modèle à anticipations adaptatives avec des chocs sans persistance qui a exactement les mêmes prédictions avec les mêmes observations disponibles. Le second inconvénient apparaît en présence d’une règle de taux d’intérêt répondant à l’inflation, où à la fois l’inflation et le taux d’intérêt seraient des variables non prédéterminées. Dans ce cas, la solution impose que le paramètre de réponse du taux d’intérêt à l’inflation engendre des spirales déstabilisatrices inflationnistes ou déflationnistes, par un effet de rétroaction positive. Cependant, ces spirales n’apparaîtraient pas du fait d’un ancrage de l’inflation sur un choc autorégressif inobservable. En revanche, ce paradoxe de « déstabilisation stabilisatrice » disparaît si on voulait bien faire l’hypothèse que le taux d’intérêt de la banque centrale est prédéterminé lorsque l’inflation n’est pas prédéterminée. Dans ce cas, la solution unique à anticipations rationnelles implique un paramètre de la règle qui stabilise l’inflation.
Robespierre, monstre ou héros ?
Authors: Pouffary Marion 
Published: March 2023

L’image de Robespierre n’est pas un bloc, comme le montre l’étude du discours public du xixe siècle, et notamment celle de la parole politique. Ce discours n’a pas jusqu’ici retenu l’attention des historiens, qui se sont concentrés sur l’historiographie, la littérature et les beaux-arts. Il révèle que la légende noire de Robespierre se scinde entre la Révolution et le milieu du xixe siècle en quatre légendes, qui peuvent être rapprochées de quatre courants politiques distincts : conservateur/contre-révolutionnaire, libéral, communiste et anarchiste. De plus, une légende dorée, peu analysée jusqu’ici, émerge dans les années 1830 chez les militants républicains les plus radicaux. Ce schéma interprétatif, présenté dans les deux premières parties de l’ouvrage, est confirmé par l’étude de l’image de Robespierre dans les débats parlementaires au xixe siècle, objet de la troisième partie. Il permet de comprendre pourquoi, plus de deux siècles après sa mort, Robespierre reste au cœur des débats sur l’héritage républicain.
Tumor Suppressor Adenomatous Polyposis Coli Sustains Dendritic Cell Tolerance through IL-10 in a β-Catenin–Dependent Manner
Authors: Cao Wei , Liu Jiamin , Jiang Zhenyan , Tao Yuexiao , Wang Huizi , Li Jia , Ni Jun , Wu Xuefeng 
Published: March 2023

Abstract
Dendritic cells (DC) play important roles in balancing immunity and tolerance, in which β-catenin signaling plays an important role, yet the underlying mechanisms remain elusive. In this study, we investigated the functions of the tumor suppressor adenomatous polyposis coli (APC), also a key component of the β-catenin upstream destruction complex in DC. APC depletion in DC does not alter DC and T cell homeostasis under resting conditions. However, APC deficiency in DC leads to attenuated antitumor immunity in mice, which exhibit fewer CD8+ T cells and more Foxp3+ regulatory T cells in tumor and draining lymph nodes. Loss of APC in DC does not affect the expression levels of costimulatory molecules. However, APC-deficient DC produce more IL-10 and exhibit a higher ability of inducing regulatory T cells but a lower ability of priming CD8+ T cells, both of which can be reversed by IL-10 inhibition. Lastly, β-catenin depletion in APC-deficient DC rescues their antitumor immunity and reverses elevated IL-10 production. Taken together, our results identify that APC drives DC tolerance via the β-catenin/IL-10 axis.
Supraglottic airway versus endotracheal tube for transesophageal echocardiography guided watchman procedures
Authors: Musuku Sridhar Reddy , Doshi Isha , Yukhvid Dmitriy , Di Capua Christopher A. , Shapeton Alexander D. 
Published: March 2023

Context:
Atrial fibrillation (AF) is the most common arrhythmia in adults. For over 90% of non-valvular AF patients, the left atrial appendage is the primary site of thrombus formation. Left atrial appendage occlusion using the FDA-approved Watchman™ device has been shown to have better clinical outcomes with minimal post-procedural complications when compared to warfarin therapy for patients with contraindications to anticoagulation. Traditionally, this procedure requires an endotracheal tube (ETT) to facilitate transesophageal echocardiography (TEE) guidance. However, recently supraglottic airway (SGA) has emerged as a feasible, non-inferior alternative to ETT for procedures requiring TEE.

Aims:
Compare outcomes between TEE guided Watchman™ procedures performed with a SGA versus ETT.

Settings and Design:
A single tertiary care academic medical center.

Methods and Materials:
Retrospective Observational Study comparing SGA and ETT patients.

Statistical Analysis Used:
1:4 propensity score matching of SGA and ETT patients.

Results:
42 SGA patients were matched with 155 ETT patients. All patients underwent procedure with TEE. SGA patients had shorter operating room time (11 min difference, P = 0.00001) and considerably shorter PACU length of stays (45 min difference, P = 0.024). Statistically significant, but clinically trivial differences were seen in procedure times (P = 0.015) and fluoroscopy times (P = 0.017). Patients in the SGA group received lower fentanyl (P < 0.00001) dosages. No significant differences were observed in postoperative complications, organ-specific morbidity or 30-day mortality.

Conclusions:
General anesthesia with SGA is likely a safe, feasible alternative to ETT in Watchman™ procedures requiring TEE guidance. Use of SGA was associated with significant reductions in operating room time and PACU length of stay, potentially offering advantages in terms of resource utilization.
A Descriptive Cross-sectional Study to Assess Knowledge Regarding Brain Death among Health Professionals in India
Authors: Bharambe Vaishaly Kishore , Vijayakumar K , Arunprasad V K , Methepatil Supriya , Jadhav Sunit , Ambike Mandar 
Published: March 2023

Context:
Brain-dead donors are one of the largest sources of organs for transplant. However, lack of knowledge about brain death may lead to delayed declaration of brain death.

Aims:
This study aimed to evaluate the knowledge about brain death among health professionals in Maharashtra state of India.

Settings and Design:
This was a descriptive, cross-sectional study.

Subjects and Methods:
The study assessed the knowledge of health professionals in Maharashtra state of India regarding brain death.

Statistical Analysis Used:
The data obtained were fed into Microsoft Excel 2010 and subsequently analyzed on SPSS.

Results:
Four hundred health professionals participated in the study between 2015 and 2017. The study found that the knowledge of brain death increased with age while no correlation with gender was observed (Pearson’s “r” = 0.7677). Seventy percent of the participants were found to have knowledge about the brain-dead category of organ donor, the highest knowledge being among the doctor category of participants and lowest among the nurse participants. Twenty-six percent of the respondents were aware of the legality of brain death. A positive correlation was found between medical college as source of knowledge and correctness of knowledge of brain death (Pearson’s “r” = 0.9789, Spearman’s rho “rs
” = 0.94286, P (two-tailed) = 0.0048, statistically significant).

Conclusions:
Medical curricula should include details of brain death-related organ donation. A health professional aware of brain death will be able to counsel the family of brain-dead donor for organ donation leading to increased availability of organs for transplantation.
Knowledge and Attitude Regarding Organ Donation among Medical and Nonmedical Students: A Comparative Study
Authors: Puri Somya , Razdan Nazuk 
Published: March 2023

Background and Objective:
Organ transplant is the treatment of choice for end-stage organ failure but there is a shortage of donor organs worldwide. Situation in India is even worse. There is a worldwide shortage of donor organs in comparison to the need for transplantation. The present study was designed with the aim to assess knowledge and attitude regarding organ donation among medical students and students pursuing courses other than medical and compare among both groups.

Materials and Methods:
The study included 200 medical students and 200 students pursuing courses other than medical. After taking informed consent, the students were given a prevalidated self-designed questionnaire having three sections to assess knowledge and attitude regarding organ donation. Data were collected, compiled, and analyzed.

Results:
On average, 98.75% of students were aware that organ donation can save life but a significantly higher number of medical students (P < 0.0001) knew brain death and that organ donation can be done during life and after death. However, willingness to donate their own organs or organs of the relative was seen among a greater number of students pursuing other courses (P < 0.001). To save someone’s life was the reason to will for organ donation among 70% of medical students.

Conclusion:
It was observed that the medical students had better awareness regarding organ donation but students pursuing other courses had a better attitude toward organ donation.
BK Virus Nephropathy in Renal Transplantation and the Effect of Intravenous Immunoglobulin: A Prospective Longitudinal Single-Center Study in South Asia
Authors: Ganesh Kartik , Abraham M. Abi , Thomas Renu Mariam , Kumar Jithin S. , Simon Sunita 
Published: March 2023

Aims and Objectives:
The aim was to assess the prevalence and treatment of BK virus nephropathy (BKVN) in patients who underwent renal transplantation at a single center in South India with a 1-year follow-up analysis. To assess the efficacy of treatment with intravenous immunoglobulin (IvIg) in cases of proven BKVN.

Materials and Methods:
Three hundred and seventy-one patients underwent renal transplantation from 2018 to 2020. All were screened for BKVN with quantitative serum polymerase chain reaction (PCR) every 3 months for 1 year after transplant. Patients with positive tests underwent renal allograft biopsy. In all patients, antimetabolite was stopped, tacrolimus dose was reduced, and leflunomide was started. All patients with biopsy-proven BKVN were administered IvIg 2 grams/kg over 5 days and had a 1-year follow-up.

Results:
Fourteen patients had BK viremia; 12 had biopsy-proven BKVN. All were male with a mean age of mean age: 45.3 years ± 14.8 standard deviation (SD). Induction: basiliximab (7) and antithymocyte globulin (ATG) (7). Maintenance immunosuppression: tacrolimus, enteric-coated mycophenolate mofetil, and prednisolone. The median presentation time was 12 months. Mean graft function: baseline S. Creatinine of 1.32 mg/dL changed to 2.01 mg/dL at diagnosis. The mean presenting BKV PCR (copies/ml) was 44912 ± 56285 SD. No significant differences were observed in time of presentation, severity, mean tacrolimus level, and graft failure between patients receiving basiliximab or ATG. There were two relapses; two grafts failed. Class I BKVN had a better prognosis. Graft survival at 1 year was 85.71%.

Conclusions:
This is the first South Asian follow-up study of BKVN in kidney transplant recipients treated with IvIg. BKVN was documented in the first 15 months after transplant. There was no increased prevalence of BKVN in patients with ATG. Histopathological class has prognostic relevance with Class I having a better prognosis. Multipronged treatment, including IvIg, leads to 1-year graft survival of 85.71%. Long-term outcomes need follow-up.
Parental awareness regarding the use of fluoride products in their children
Authors: Vijai S. , Kumar R. Krishna , Peter Joby , Anaswara M. S. , Vrinda M. P. 
Published: March 2023

Introduction:
Oral health is an integral part of general health and has an impact on the quality of life of children. Proper oral hygiene along with nutrition, regular dental visits, and fluoride (F) prophylaxis has got a significant impact on the oral health of children. Mostly, the family provides background for the development of knowledge regarding the use of F products among children. Hence, the aim of this study is to evaluate parental knowledge about the use of F products in children. The study included 356 correctly filled-in questionnaires from randomly chosen parents of children which were circulated through social platforms.

Materials and Methods:
The questionnaire contained 21 questions relating to F products used by children, as well as their benefits and usage limitations. For statistical analysis, descriptive statistics were performed.

Results:
More than 80% of parents have heard of F, and the main source of information was television/newspaper. Out of the parents, 59% of them believe that F can reverse early-stage tooth decay, whereas the other half do not agree with this. A very less number of parents are aware of the professional F treatments available in dental clinics. As per this study, 28.7% of school-going children had participated in school-based F preventive treatment. Among the mothers, 76% of them have not used any F-containing medications during pregnancy. Most of the respondents have not heard of the term fluorosis and are unaware of its symptoms.

Conclusion:
There is an association between the female gender and knowledge about the benefits of F prevention. The parental knowledge about oral hygiene and anticaries prevention with the use of F in children is insufficient. Most parents are neither familiar with the type of toothpaste their children should use nor aware of the proper amount of dentifrice to apply on a toothbrush. Dentists would be able to guide them by providing proper knowledge regarding F use. Care must be taken to ensure that a balance is maintained between maximizing the protective F effect against dental caries and minimizing the risk of dental fluorosis.
Prevalence and Heritability of Dental Caries and Malocclusion in Haryana: A Family-Based Study
Authors: Tariq S , Thakur P , Gupta N , Gupta P , Sharma A 
Published: March 2023

Background:
Genetics could be one of the factors in determining oral health and disease in families and the interplay of genetics with environmental factors can affect the prevalence of oral diseases.

Aim:
To evaluate the genetic influence on dental caries and malocclusion.

Objective:
To assess the prevalence of dental caries and malocclusion in the family tree.

Materials and Methods:
A descriptive study was conducted among 26 families of Barwala, District Panchkula, Haryana, India. Clinical examination was conducted to assess dental caries [Decayed Filled Surface Index (DFS/dfs)] and malocclusion (Dental Aesthetic Index). Heritability within the study population was assessed within the pairs: grandparent–grandchildren pair and parent–children pair. Data were analyzed in IBM SPSS Statistics version-24.

Results:
Dental caries prevalence in grandfather–grandchildren pairs was 35.29% as compared to grandmother–grandchildren pair (36.36%), whereas father–children pair had 38% and mother–children pair had 42.59%. Statistically significant results were obtained for caries in grandmother–grandchildren pairs, father–children pair, and mother–children pair but not for grandfather–grandchildren. The prevalence of malocclusion in grandfather–grandchildren pairs was 70.58% as compared to grandmother–grandchildren pairs (13.63%), whereas the father–children pair had 52% and mother-children pair had 20.37%. Statistically, a significant result was obtained for a malocclusion among grandparent–grandchildren pair and parent–children pair.

Conclusion:
This study attempts at defining genetic implications in dental caries and malocclusion process. Caries prevalence was higher in mother–children pairs than in the father-children pair. The grandfather–grandchildren pairs had a higher prevalence of malocclusion than grandmother-grandchildren pairs. Thus, the study leads to improved understanding and prevention of the factors leading to them.
Implementation and Evaluation of Community Participatory Oral Health Program in School Children from Select Rural Population in Deshmukhwadi, Pune District
Authors: Shinde P , Shetiya SH , Agarwal D 
Published: March 2023

Introduction:
In order to reduce the oral health disparities among school children in rural areas and provide a sustainable program, a pilot project using community health workers was planned.

Aim and Objectives:
The objectives of the study were to implement and evaluate community participatory oral health promotion and prevention program in school children from select rural population in Deshmukhwadi, Pune district, and also carry out knowledge, attitude and practice survey among health workers and school teachers about oral health.

Materials and Methods:
One hundred and thirty-nine students, aged 6–13 years, constituted the sample size. The program consisted of oral health education, atraumatic restorative treatment, scaling of teeth with hand scalers, and fortnightly fluoride mouth rinsing. The health workers who were commissioned into medical department by Tata Motors from the same village, after proper training and calibration performed the above-mentioned preventive procedures on children.

Results:
There was a significant improvement in gingival status (P
< 0.001), caries status (P = 0.003), and incipient lesion (P = 0.01) after the program. In the present study, the health workers were successfully trained to provide basic oral care services in rural areas. Furthermore, the knowledge, attitude, and practice regarding oral health which was assessed among the health workers and school teachers improved after 16 months of the program.

Conclusions:
The community participatory oral health promotion and prevention program showed a significant improvement in the filled and initial lesion surfaces in the primary and permanent dentition and the bleeding sextants. Health workers and school teachers showed improvement in knowledge and practice after the program.
Evaluating the Knowledge and Attitude of Dental Residents about Special Care Dentistry – A Cross-Sectional Study
Authors: Sangeetha R , Charan KV , Santana N , Anand B , Kumari M 
Published: March 2023

Introduction:
Special care Dentistry (SCD) refers to the management of oral health, exclusively for individuals with special care requirements, by adopting an alternative way in spite of the numerous advancements in the field of Dentistry in the present day scenario, the oral health among the special care population remains poor. In numerous countries, SCD has been introduced as a separate specialty, in India, it is still in its initial stage.

Aim:
The aim of the study was to evaluate knowledge and attitude among dental residents about SCD.

Materials and Methods:
This cross-sectional observational study was conducted in various dental colleges in Chennai from January 2022 to July 2022. A total of 100 dental residents interested in participating in this survey were included in this study. A set of 11 multiple-choice questions were formulated and directed to dental residents. Descriptive statistics were performed using SPSS software.

Results:
87% of the participants are aware of the term SCD, and the majority of them have come across patient with special care needs during their internship period, but their confidence level (94%) in delivering the treatment to this population remains relatively less. The reason for reluctance was lack of training, unavailability of special set-up, and their curriculum does not cover any lectures about SCD. Majority of participants 88% perceive that there must be a separate specialty on SCD in the future.

Conclusion:
Incorporation of SCD in the curriculum as a separate specialty will pave the way for more clinical exposure and help in developing a positive attitude and confidence among students while treating patients with special needs.