bluuebunny/crossref_metadata_2025_split huggingface dataset:
Public environmental landscape art design based on the concept of sustainable development
Authors: Chen HanYi , Lin YounJien , Chen HanYun , Lu ChiHen 
Published: August 2023

Abstract
Since the beginning of the 21st century, the material civilization and spiritual civilization of our human society have developed rapidly, and the concept of harmonious coexistence between man and nature has also been deeply rooted in the hearts of the people. Therefore, we are more aware of the importance of sustainable development. fields, economy, natural ecology, international relations, science and technology, engineering design, educational thinking, etc. How to meet the needs of the contemporary people without harming the interests of future generations and even long-term stable development is the core of the concept of sustainable development. In today's world, the excessive waste of resources and development have led to serious damage to the ecological environment, and some damages are even irreversible. In the context of the contradiction between man and nature, contemporary design projects such as architecture and landscape design also need to learn sustainable development concept. This paper analyzes and studies some currently developing and perfect landscape design ideas in line with the concept of sustainable development, so that the concept of sustainable development in the field of landscape design can penetrate into our engineering design blueprint and realize it.
R-spondin-1 induces Axin degradation via the LRP6-CK1ε axis
Authors: Tan Lifeng , Su Zijie , Yan Mengfang , Li Huan , Zhao Xibao , Liu Shanshan , Sun Qi , Lu Desheng 
Published: August 2023

Abstract
R-spondins (RSPOs) are secreted signaling molecules that potentiate the Wnt/β-catenin pathway by cooperating with Wnt ligands. However, the molecular mechanism by which RSPOs activate Wnt/β-catenin signaling remains elusive. In this study, we found that RSPOs could mediate the degradation of Axin through the ubiquitin-proteasome pathway. The results of Co-IP showed that recombinant RSPO1 protein induced an enhanced interaction between Axin1 and CK1ε. Either knockout of CK1ε gene or treatment with the CK1δ/CK1ε inhibitor SR3029 caused an increase in Axin1 protein level, and attenuated RSPO1-induced degradation of Axin1 protein. Moreover, we observed the increased association of LRP6 with CK1ε and Axin1 following RSPO1 stimulation. Overexpression of LRP6 further potentiated Axin1 degradation mediated by RSPO1 or CK1ε. In addition, recombinant RSPO1 and Wnt3A proteins synergistically downregulated protein expression of Axin1 and enhanced the transcriptional activity of the SuperTOPFlash reporter. Taken together, this study uncovers a novel mechanism by which RSPOs activate Wnt/β-catenin signaling through a LRP6/CK1ε-mediated degradation of Axin.
Hygrothermal stress increases malignant arrhythmias susceptibility by remodeling connexin43 via AMPK
Authors: Chi Jianing , Li Pengfei , Wu Ningxia , Hu Jiaman , Cai Hua , Lin Cailong , Lai Yingying , Yang Han , Huang Jianyu , Li Min , Xu Lin 
Published: August 2023

Abstract
High mortality due to hygrothermal stress (high temperature and humidity, HHS) during heat waves is mostly linked to cardiovascular malfunction, the most serious of which are malignant arrhythmias. However, the mechanism associated with HHS leading to malignant arrhythmias remains unclear. Here, SD rats were exposed to 40°C and 85% humidity for constructing the HHS model, and the incidence of arrhythmic events, as well as the expression, phosphorylation, and distribution of Cx43 in the myocardium, were examined. The adenosine monophosphate-activated protein kinase (AMPK) activator, AICAR, was also administered to investigate the role played by AMPK in the process. Our results showed that HHS could induce malignant arrhythmias such as ventricular tachycardia (VT), ventricular fibrillation (VF), and severe atrioventricular block (AVB). Besides, HHS increased the distribution of "side-to-side" connections, decreased the phosphorylation of Cx43, and enhanced myocardial fibrosis. Furthermore, HHS also caused LKB1 and p-AMPK expression to be less abundant. While, pretreatment with AICAR could significantly ameliorate Cx43 remodeling and malignant arrhythmias, indicating that the HHS-induced arrhythmias is associated with the redistribution of gap junctions in cardiomyocytes, the dysfunction of intercellular conduction, and the organism's energy metabolism.
Risk Factors Analysis of Postoperative Atrial Fibrillation in Video-assisted thoracoscopic surgery for Non-Small Cell Lung Cancer Resection
Authors: Ruan Yingding , Han Jianwei , Yang Aiming , Ding Qingguo , Xu Jincheng , Zhang Ting 
Published: August 2023

Abstract
Objective: Postoperative atrial fibrillation ( POAF ) is a frequent complication after lung cancer resection. To identify potential intervention targets, this study aimed to analyze risk contributing factors to the development of POAF in patients undergoing video-assisted thoracoscopic surgery ( VATS ) for non-small cell lung cancer ( NSCLC ) resection.
Methods: A retrospective analysis was performed on a cohort of patients who underwent VATS for NSCLC resection at our hospital between January 2016 to October 2019. Patient demographics, preoperative data, and postoperative outcomes were collected and reviewed. Univariate and multivariate analyses were performed to identify significant risk factors for POAF.
Results: Among 276 patients who underwent VATS for NSCLC, 29 ( 10.5 % ) developed POAF during hospitalization, and there were no deaths during hospitalization. 25 cases ( 86.2 % ) of POAF occurred within the first three days after surgery. The study established a cut-off age of 73 years, and when patients ' age exceeded this threshold. The incidence of POAF was significantly higher compared to the n-POAF group ( [ 10 ( 34.5 % ) vs. 46 ( 18.6 % ), P = 0.045 ] ). In addition, compared to the n-POAF group, the mediastinal lymph nodes retrieved and node stations explored were significantly higher in the POAF group ( [ median nodes: 10 ( 5,14 ) vs. 6 ( 0,11 ), P = 0.011; median node stations : 3 ( 3, 4 ) vs. 3 ( 0, 3 ), P = 0.005 ). Moreover, the POAF group had higher intraoperative bleeding volume [ 100 ( 50,100 ) vs. 100 ( 100, 200 ) ]. P = 0.034 ] ) and postoperative pulmonary infections ( [ 15 ( 51.7 % ) vs. 55 ( 22.3 % ). The study also identified a significant difference in preoperative hemoglobin levels between the POAF and n-POAF groups ( [ ( 117.63 ± 19.79 ) vs. ( 125.06 ± 16.30 ), P = 0.024] ). Compared to the n-POAF group, the postoperative hospitalization and drainage time were significantly longer in the POAF group ( [ postoperative hospitalization: 11 ( 9, 14 ) vs. 9 ( 6, 12 ), P = 0.024; drainage time: 7 ( 5, 9 ) vs. 5 ( 4, 8 ), P = 0.011 ). Multivariate analysis indicated that postoperative pulmonary infection ( OR: POAF group / n-POAF group = 0.349; 95 % CI 0.149-0.821 ) was an independent risk factor for POAF following VATS for NSCLC.
Conclusion: Our study revealed that pulmonary infection was one of the independent risk factors for POAF following VATS in patients with NSCLC. Furthermore, POAF is associated with prolonged drainage time and extended postoperative hospitalization.
An asymptotic property of quaternary additive codes
Authors: Bierbrauer Jürgen , Marcugini Stefano , Pambianco Fernanda 
Published: August 2023

Abstract

Let nk(s) be the maximal length n such that a quaternary additive [n, k, n − s]4-code exists. We solve a natural asymptotic problem by determining the lim sup λk of nk(s)/s, and the smallest value of s such that nk(s)/s = λk. The proof uses geometric language and is elementary.
Mathematics Subject Classification. 94Bxx, 51E22.
Changes in leaf structure and control of Conyza spp. by herbicides applied in the presowing desiccation of soybean
Authors: Silva Paulo Vinicius , Schedenffeldt Bruna Ferrari , Medeiros Elias Silva , Bicalho Carolina Cristina , Salmazo Pedro Antônico Vougodo , Barros Daniela Maria , Monquero Patrícia Andrea , Munaro Fernando Cesar , Mauad Munir , Dias Roque Carvalho , Borges Rafael Pereira Nascimento 
Published: August 2023

Abstract

The presowing desiccation of Conyza spp. is an important practice to reduce weed competition with soybean, and the applications of post-emergent herbicides, as an alternative to 2,4 D, promote changes in the leaf anatomy of horseweed. The objective of the present study was to evaluate the effect of post-emergent herbicides on the leaf structure and chemical control of Conyza spp. with heights greater than 10 cm in soybean presowing desiccation. A field experiment was conducted following a randomized block design, with seven treatments and four replicates. For the control data, only mesotrione + atrazine and chlorimuron resulted in control percentages lower than 80%. Regarding scanning electron microscopy (SEM), trichomes showed higher density in the adaxial part and stomata in the abaxial part, although they were present on both sides. Both trichomes and stomata showed clustering and random distribution tendencies. The control and halauxifen + diclosulam showed greater intensity of trichomes and less damage to these structures, while fluroxypyr + clethodim, dicamba and tryclopyr showed lower intensity. Therefore, fluroxypyr + clethodim and tryclopyr, dicamba and halluxifen + diclosulam were effective in the desiccation of Conyza spp., and the first two caused disruption of the trichomes due to plasmolysis.
Latent tuberculosis infection and COVID-19: analysis of a cohort of patients from Careggi University Hospital (Florence, Italy)
Authors: Mariotti Francesca , Sponchiado Francesco , Moroni Chiara , Lagi Filippo , Paggi Riccardo , Kiros Seble Tekle , Miele Vittorio , Bartoloni Alessandro , Mencarini Jessica 
Published: August 2023

Abstract
Background.
In the available literature, data regarding the relationship between the Coronavirus-19 disease (COVID-19) and active or latent tuberculosis (TB) are few and discordant.
Methods.
We conducted a retrospective study to examine the impact of latent tuberculosis infection (LTBI) on COVID-19 clinical progression and in-hospital mortality in a pre-vaccinal era and in a low-TB prevalence area. We selected 213 patients out of 495 admitted with COVID-19 in a tertiary-level Italian hospital from February to December 2020, who underwent QuantiFERON-TB test (QFT) and/or chest radiological exam.
Results.
Based on QFT result and radiological findings, the population was divided into three groups: (i) QFT negative and without radiological TB sequelae (Neg, 76.1%); (ii) QFT positive and without radiological TB sequelae (Pos, 7.0%); (iii) radiological TB sequelae regardless of QFT result (Seq, 16.9%). In-hospital mortality and orotracheal intubation (OTI) resulted significantly higher in Seq group than in the other two cohorts (respectively, Seq 50% vs Pos 13.3% vs Neg 9.3%, p < 0.001; Seq 16.7% vs Pos 6.7% vs Neg 4.9%, p = 0.04). Considering Pos and Seq cohorts as populations with defined LTBI, in-hospital mortality (39.2%, p < 0.001) and OTI risk (13.7%, p = 0.02) were statistically higher in respect to patients without LTBI. By multivariate analysis, we evidenced that Charlson Comorbidity Index and belonging to Seq group were significantly associated with the three groups in-hospital mortality.
Conclusion.
Latent tuberculosis infection appears significantly more common in patients presenting with severe COVID-19 than non-severe disease, with a significantly higher risk of in-hospital mortality and OTI.
The fundamental theorem of tropical differential algebra for formal Puiseux series
Authors: Falkensteiner Sebastian , Mereta Stefano 
Published: August 2023

Abstract
The fundamental theorem of tropical differential algebra has been established for formal power series solutions of systems of algebraic differential equations. It has been shown that the direct extension to formal Puiseux series solutions fails. In this paper, we overcome this issue by transforming the given differential system and such a generalization is presented. Moreover, we explain why such transformations do not work for generalizing the fundamental theorem to transseries solutions, but show that one inclusion still holds for this case even without using any transformation.
2010 Mathematics Subject Classification. Primary 14A20; Secondary 12H99, 13N99, 14T05, 14T99.
Anisotropic carbon matrix derived from cellulose aerogel decorated wood plate serving as self- supporting hosts for cathodes in lithium sulfur batteries with enhanced cycling stability
Authors: Yan Yinglin , Zhang Xingsheng , Jing Wei , Liu Pufang , Song Muze , Fan Chaojiang , Xu Rongfu , Zou Yiming , Deng Qijiu , Wang Xianhui , Zhong Lisheng , Yang Rong , Xu Yunhua 
Published: August 2023

Abstract
Lithium-sulfur batteries, as a promising electrochemical energy storage device, are impeded by sluggish reaction kinetics and poor cycle life under high sulfur loading. Herein, a natural wood disc derived carbon matrix with anisotropic and aligned microchannels decorated with carbonized cellulose aerogel was proposed to serve as a host for self-supporting sulfur/carbon composite cathodes (S/DBWC/CCA) in Li-S batteries. The obtained cathodes were capable of high sulfur areal loading (3.1 and 6.3 mg cm-2). Furthermore, exceptional cycling stabilities were achieved not only under a high current density (1 C) but also under a high sulfur areal loading of 6.3 mg cm-2. The improved performance is attributed to the synergistic effect of the ordered microchannels with low tortuosity and 3D conductive network of carbonized cellulose aerogel. This work provides an ideal host derived from natural resources for viable Li-S batteries with excellent cycling stability, which is a potential strategy for structural design of advanced energy storage devices.
One-pot, green synthesis of 1H-pyrazolo [1, 2-b] phthalazine-5, 10 diones by ZnFe 2 O 4 nanoparticles an efficient nanocatalyst
Authors: K Mhaske A. , G Gadhave A. , G Dholi A. , K Uphade B. 
Published: August 2023

Abstract

Zinc ferrite (ZnFe2O4) nanoparticles were synthesized in the presence of naturally available lemon juice. The synthesized zinc ferrite nanoparticles were characterized by FT-IR, XRD, SEM, EDX, and BET techniques. The zinc ferrite nanoparticles were used for the synthesis of 1H-pyrazolo[1,2-b] phthalazine-5,10-dione derivatives by one-pot coupling reaction of phthalhydrazide, aromatic aldehyde, and malononitrile under conventional reflux condition. This green synthetic approach offers important features like non-toxic substances, maximum yields with a short reaction time, and easy purification of a product. It is a highly efficient, cheap, and reusable nanocatalyst.
Generation of biochars for gas separation upon cellulose pyrolysis: A reactive molecular dynamics study
Authors: Barzegar Behnoush , Feyzi Farzaneh 
Published: August 2023

Abstract
The pyrolysis of cellulose via reactive molecular dynamic simulation to obtain an adsorbent for CO2 separation is the main goal of the present study. Biochars with six different densities ranging from 0.160-0.987 g/cm3 were produced and adsorption of pure CO2, CH4, N2 and mixtures of CO2 (0.05)/CH4 (0.95) and CO2 (0.2)/N2 (0.8) at 300 K was investigated as a function of pressure by Grand Canonical Monte Carlo simulations. Dual-site Langmuir (DSL) model was adjusted to the isothermal adsorption data with very good accuracy. Thermodynamic quantities were calculated based on the DSL parameters which showed that the amount of adsorbed CH4 and N2 decreases as the density of biochar increases. Adsorption isotherms, selectivity, and isosteric heat were calculated, which revealed that the biochar with 0.351 g/cm3 density had the highest selective adsorption of CO2. The higher Gibbs free energy and surface potential of pure CO2 indicated that CO2 adsorption on biochars is more favorable and spontaneous than CH4 and N2. Henry's constant for CH4 and N2 was smaller than that of CO2, which indicates that their affinity for biochar surfaces was weaker than CO2. The higher entropy changes of CO2 adsorption of pure gases and binary gas mixtures showed that CO2 molecules constitute a much more stable rearrangement than CH4 and N2. We may conclude that pyrolysis of cellulose, as a cheap and available material, can be used to make an economic structure with high ability for CO2 separation.
Urinary microbiota is associated to clinicopathological features in benign prostatic hyperplasia
Authors: Arap Marco , Mariotti Antonio , Heidrich Vitor , Inoue Lilian , Coser Elisangela , Santos Ernande dos , Santos Hugo dos , Rocha Carolina , Asprino Paula , Bettoni Fabiana , Bastos Diogo , Jardim Denis , Camargo Anamaria 
Published: August 2023

AbstractBackground the urinary microbiota of patients with benign prostatic hyperplasia (BPH) has been associated with lower urinary tract symptoms (LUTS), however, little is known about urinary microbiota correlations with clinical clinicopathological parameters associated with BPH. Here, we investigate associations between the urinary microbiota and clinical parameters of patients with BPH undergoing surgery. Methods Forty-one patients with BPH undergoing surgery were recruited from two medical centers. Catheterized urine specimens were collected and the microbiota was characterized by 16S rRNA gene sequencing. Patients were segregated into two groups according to each clinical parameter and differences in urinary microbiota diversity and composition were evaluated. Results Higher prostate weight and PSA levels were associated with higher alpha-diversity in the urinary microbiota of BPH patients. At the specific-microbe level, we found that the greater the prostatic weight, the lower the relative abundance ofStreptococcus, while the greater the PSA levels, the higher the abundance ofLactobacillus. Treatment with 5-α-reductase inhibitor was associated with overall urinary microbiota composition, in part due to a higher abundance ofCorynebacteriumandAnaerococcusin this group. Conclusions We demonstrated that the urinary microbiota of BPH patients is associated with clinicopathological features, highlighting a possible role of urinary microbes in the BPH clinical course.
Otoscopy-Assisted Intranasal Cyst Marsupialization for Congenital Dacryocystocele
Authors: MD  , MD  , MD  , MD  , MD  , MD  
Published: August 2023

Abstract

Purpose
We report a novel, simple intranasal cyst marsupialization (ICM) technique for congenital dacryocystocele (CDC).
Design:
Prospective observational study
Methods
Twenty consecutive infants with 25 CDCs treated at our facility from 2011 to July 2023 were enrolled. Five infants with five CDCs required surgical interventions due to resistance to conservative treatment. Among these five infants, we evaluated the surgical method and the outcomes in three infants with three CDCs who underwent otoscopy-assisted ICM.
Results
Of the total 25 CDCs, 20 (80%) spontaneously resolved with conservative treatment. Surgical intervention was conducted on five consecutive infants with five CDCs. The median age at surgery was 97 days, with an interquartile range of 39–164.5 days. The surgical procedures involved one of the following methods: (1) Probing by an ophthalmologist (2 CDCs); (2) Otoscopy-guided ICM performed by an otolaryngologist in the manner of otoscopic myringotomy (3 CDCs). All infants were treated successfully by a single surgical procedure under topical anesthesia in an office setting.
Conclusion
CDC was successfully treated by ICM in the manner of an otoscopic myringotomy. Treatment of CDC using an otoscope and myringotome is a minimally invasive surgical procedure that can be performed in an office setting without the need for general anesthesia or advanced medical equipment such as a nasal endoscope. Moreover, the risk of false passage formation and/or recurrence after probing can be avoided. Therefore, we propose this procedure as one of the practical ICM techniques for CDC.
Numerical treatment for studying radiated power-law nanofluid flow past a nonlinearly stretching sheet under the viscous dissipation phenomena and non-uniform heat generation
Authors: Khader M. M. , Megahed Ahmed M. , Eid A. 
Published: August 2023

Abstract
A research investigation is performed to examine the impact of non-uniform heat generation and viscous dissipation on the boundary layer flow of a power-law nanofluid over a non-linearly stretching sheet. Within the thermal domain, the analysis takes into account both thermal radiation and variable thermal conductivity. Through the utilization of similarity transformations , the governing boundary layer equations are transformed and simplified into a system of ordinary differential equations. The spectral collocation method with shifted Vieta-Lucas polynomials is employed to provide an approximate expression for the n-order derivative and numerically solve the given system of equations. By employing this technique, the system of ordinary differential equations is transformed into a nonlinear system of algebraic equations. The dimensionless temperature, concentration and velocity are graphically presented and analyzed for different values of the relevant governing parameters. The graphical solutions are discussed in detail. The accuracy of the numerical results is validated by comparing them at some special cases with existing literature, revealing a strong resemblance between the current findings and the provided data, thereby affirming the precision of the proposed numerical method.
MSC 2010: 41A30; 65N12; 65M60; 76F12.
Decreased peripheral blood lymphocyte to monocyte ratio, platelet to lymphocyte ratio, platelet to monocyte ratio and platelet to albumin ratio predict poor survival in newly diagnosed Multiple Myeloma patients
Authors: Zhang Yan , Shou Lihong , Fang Qiu , Fei Juping , Xu Baolian , Cao Dan , Wu Ying , Dong Xiaohui , Lu Wentian , Zhang Zongxin , Chen Yelong , Dai Menglu 
Published: August 2023

Abstract
Background. Multiple myeloma (MM) is a clonal malignant tumor with abnormal proliferation of Plasma cell, ranking second in the incidence rate of common malignant tumors in the blood system. The clinical manifestations, treatment responses, and prognosis of patients are highly heterogeneous. Therefore, optimal strategies for identifying high-risk patients are urgently needed.
Materials and Methods. We retrospectively studied 145 newly diagnosed MM patients from January 2013 to December 2020 and analyzed the relationship between peripheral blood lymphocyte-monocyte ratio (LMR), platelet-lymphocyte ratio (PLR), platelet-monocyte ratio (PMR), platelet-albumin ratio (PAR) and prognosis.
Results. The receiver operating characteristic (ROC) curve was used to determine the optimal cut-off value based on survival rate. It was found that patients with MM with LMR ≤ 2.55, PLR ≤ 117, PMR ≤ 181 and PAR ≤ 3.38 had inferior overall survival (OS). In multivariate analysis, LMR ≤ 2.55 (HR = 0.243, 95% CI 0.099–0.596, p = 0.002), PLR ≤ 117 (HR = 0.222, 95% CI 0.072–0.680, p = 0.008), PAR ≤ 3.38 (HR = 0.293, 95% CI 0.107–0.804, p = 0.017) and Serum creatinine ≥ 177umol/l (HR = 2.599, 95% CI 1.086–6.218, p = 0.032) were independently associated with short survival. The more items that simultaneously meet LMR ≤ 2.55, PLR ≤ 117, PMR ≤ 181 and PAR ≤ 3.38, the worse the prognosis of the patients (P = 0.000). The 2-year OS of patients with reduced four ratios was only 32%, and the 3-year OS was only 16%.
Conclusion. The pre treatment LMR, PLR, PMR and PAR of MM patients are closely related to their prognosis. Moreover, LMR, PMR, and PAR are independent prognostic indicators for MM patients. We can use them for initial screening and stratification of MM patients. It is simple, convenient and accurate to screen out patients with short lives, and formulate personalized treatment strategies.