bluuebunny/crossref_metadata_2025_split huggingface dataset:
The SWADE model for landslide dating in time series of optical satellite imagery
Authors: Fu Sheng , de Jong Steven M. , Deijns Axel , Geertsema Marten , de Haas Tjalling 
Published: January 2023

AbstractLandslides are destructive natural hazards that cause substantial loss of life and impact on natural and built environments. Landslide frequencies are important inputs for hazard assessments. However, dating landslides in remote areas is often challenging. We propose a novel landslide dating technique based on Segmented WAvelet-DEnoising and stepwise linear fitting (SWADE), using the Landsat archive (1985–2017). SWADE employs the principle that vegetation is often removed by landsliding in vegetated areas, causing a temporal decrease in normalized difference vegetation index (NDVI). The applicability of SWADE and two previously published methods for landslide dating, harmonic modelling and LandTrendr, are evaluated using 66 known landslides in the Buckinghorse River area, northeastern British Columbia, Canada. SWADE identifies sudden changes of NDVI values in the time series and this may result in one or more probable landslide occurrence dates. The most-probable date range identified by SWADE detects 52% of the landslides within a maximum error of 1 year, and 62% of the landslides within a maximum error of 2 years. Comparatively, these numbers increase to 68% and 80% when including the two most-probable landslide date ranges, respectively. Harmonic modelling detects 79% of the landslides with a maximum error of 1 year, and 82% of the landslides with a maximum error of 2 years, but requires expert judgement and a well-developed seasonal vegetation cycle in contrast to SWADE. LandTrendr, originally developed for mapping deforestation, only detects 42% of landslides within a maximum error of 2 years. SWADE provides a promising fully automatic method for landslide dating, which can contribute to constructing landslide frequency-magnitude distributions in remote areas.
The Effects of Vibratory and Acoustic Stimulations on Postural Control in Healthy People: A Systematic Review
Authors: Minino Roberta , Romano Antonella , Troisi Lopez Emahnuel , Liparoti Marianna , Sorrentino Pierpaolo , Fratini Antonio 
Published: January 2023

AbstractResearch on human posture and balance control has grown in recent years, leading to continued advances in their understanding. The ability to maintain balance is attributed to the interplay of the visual, vestibular, and somatosensory systems, although an important role is also played by the auditory system. The lack or deficit in any of these systems leads to a reduced stability that may be counterbalanced by the integration of all the remaining sensory information. Auditory and vibratory stimulation have been found to be useful to enhance balance alongside daily activities either in healthy or pathological subjects; nevertheless, while widely investigated, the literature relating to these approaches is still fragmented. This review aims at addressing this by collecting, organising, and discussing all the literature to date on the effects of the various acoustic and vibratory stimulation techniques available on static upright posture in healthy subjects. In addition, this review intends to provide a solid and comprehensive starting point for all the researchers interested in these research areas. A systematic search of the literature was performed and a total of 33 articles (24 on vibratory stimulation and 9 on acoustic stimulation) were included in our analysis. For all articles, several elements were highlighted including: the study sample, the characteristics of the stimulations, the recording instruments, the experimental protocols, and outcomes. Overall, both stimulations analysed were found to have a positive effect on balance but more research is needed to align those alternative approaches to the traditional ones.
Cuticular Hydrocarbon Polymorphism in a Parasitoid Wasp
Authors: Pokorny Tamara , Ruther Joachim 
Published: January 2023

AbstractCuticular hydrocarbons (CHCs) are major constituents of the cuticular lipid layer of insects. They serve not only as a barrier to desiccation, but often additionally mediate communication at close range. The compositions of the CHC profiles, i.e., the specific compounds and their relative amounts, usually differ between species. Additional intraspecific variability can be found between different populations, between colonies and castes of social insects, and between the sexes. Thus, such groups can often be distinguished based on distinctive compounds and/or specific compound ratios. The CHC profile may further be influenced by biotic and abiotic factors, which therefore can impact, e.g., nestmate recognition or mate choice. However, consistent intrasexual variation seems to be rare. Here, we investigated a case of intrasexual CHC variability within a single population of a parasitoid wasp. While wasps of both sexes produced the same set of compounds, the relative amounts of specific compound classes revealed the presence of intrasexual chemical phenotypes. This is, to our knowledge, the first report of three distinct female CHC profile patterns within a population of a solitary insect that uses CHCs for mate recognition. Additionally, male CHC profiles, while overall very similar, could be separated into two chemotypes by multivariate analysis. The study of species exhibiting such intraspecific and intrasexual CHC variation will advance our understanding of the effects of CHC variability on both, desiccation resistance and intraspecific communication.
The Activity of Vossia cuspidata Polysaccharides-Derived Monometallic CuO, Ag, Au, and Trimetallic CuO-Ag-Au Nanoparticles Against Cancer, Inflammation, and Wound Healing
Authors: Abd El-Aziz Salim Mohamed , Farahat Emad A. 
Published: January 2023

AbstractThe biosynthesis of metal nanoparticles using plant extracts is an eco-friendly and inexpensive solution that has strong potential and applications in science and industry. This study aims to synthesize Cu, Ag, and Au monometallic and trimetallic nanoparticles (NPs) using the extracted polysaccharides (PS) of Vossia cuspidata (Roxb.) Griff. leaves. Besides, the anti-cancer, anti-inflammatory, and wound healing potentials of the synthesized NPs were tested. The synthesized NPs were characterized using standard technological methods. We succeeded in green synthesizing CuO, Ag, Au, monometallic, and CuO-Ag-Au trimetallic NPs. The synthesized NPs had weak cytotoxicity at low concentrations (6.5 µg/ml), but the viability of cancer cells was reduced by increasing the concentration, suggesting that the synthesized NPs have potent anti-cancer properties against the cells. The synthesized NPs had 19.44–45.9 μg/ml cytotoxic activity (IC50) against the MCF-7 cell line, 16.50–51.92 μg/ml against A549, and 115.90–165.9 μg/ml for normal lung cells (WI-38). TMNPs were the most effective cytotoxic agents against all the tested cell lines, followed by AuNPs on MCF-7 and CuONPs on A549. The cotton fabric-treated TMNPs and CuONPs exhibited anti-inflammatory properties greater than fabric-treated AgNPs and AuNPs and showed the highest odema inhibition (84.61% and 79.28%, respectively). In the wound healing assay, CuONPs and TMNPs caused the highest percentages of inhibition (87.82% and 61.98%, respectively) for the wound compared to AgNPs and AuNPs. TMNPs and CuONPs were more efficient in restoring the tissue integrity of wounds than AgNPs and AuNPs. Accordingly, we recommend using TMNPs and CuONPs in the wound healing dressings.
Contribution of household dishwashing to microplastic pollution
Authors: Sol Daniel , Menéndez-Manjón Andrea , Carrasco Sofía , Crisóstomo-Miranda Jacinto , Laca Amanda , Laca Adriana , Díaz Mario 
Published: January 2023

Abstract
At household level, clothes washing has been recognised as an emitter of microplastics (MPs) into the environment and it is supposed that dishwashing is also a source of MPs, although little attention has been paid so far. In this work, the emission of MPs released from dishwashing procedures at household level has been studied. The effect of different parameters such as time, temperature and type of detergent has been analysed. In addition, the MP content of tap water has been evaluated in order to determine its contribution to the MPs in dishwasher effluent. Results showed that when the dishwasher was operated empty with a pre-wash programme (15 min and room water temperature), between 207 and 427 MPs were released per load (3 L), whereas this value increased notably with an intensive programme (164 min and water at 70 °C) (1025–1370 MPs per load, 15 L), which highlighted the effect of temperature and time on MP release. Additionally, when a polypropylene lunch box was washed, the number of MPs released increased by 14 ± 3 MPs and 166 ± 12 MPs of total. Finally, the influence of the use of detergent with the dishwasher empty and containing lunch boxes has been studied. With detergent, 35–54% more MPs were released from dishwasher accessories, whereas no additional release took place from lunch boxes. This work shows for the first time the important contribution of domestic dishwashing to MP pollution and the environmental benefits of using more environmentally friendly materials in both dishwashing machine accessories and food utensils.
Small-Molecule Compounds Boost CAR-T Cell Therapy in Hematological Malignancies
Authors: Cao Xinping , Jin Xin , Zhang Xiaomei , Utsav Paudel , Zhang Yi , Guo Ruiting , Lu Wenyi , Zhao Mingfeng 
Published: January 2023

Opinion statementAlthough chimeric antigen receptor T cell immunotherapy has been successfully applied in patients with hematological malignancies, several obstacles still need to be overcome, such as high relapse rates and side effects. Overcoming the limitations of CAR-T cell therapy and boosting the efficacy of CAR-T cell therapy are urgent issues that must be addressed. The exploration of small-molecule compounds in combination with CAR-T cell therapies has achieved promising success in pre-clinical and clinical studies in recent years. Protein kinase inhibitors, demethylating drugs, HDAC inhibitors, PI3K inhibitors, immunomodulatory drugs, Akt inhibitors, mTOR inhibitors, and Bcl-2 inhibitors exhibited potential synergy in combination with CAR-T cell therapy. In this review, we will discuss the recent application of these combination therapies for improved outcomes of CAR-T cell therapy.
Pulmonary barotrauma in SCUBA diving-related fatalities: a histological and histomorphometric analysis
Authors: Casadesús Josep M. , Nieto-Moragas Javier , Serrando Maria T. , Boadas-Vaello Pere , Carrera Ana , Aguirre Fernando , Tubbs R. Shane , Reina Francisco 
Published: January 2023

AbstractArterial gas embolism following pulmonary barotrauma occurs in 13–24% of cases of diving deaths. The study aimed to evaluate the usefulness of a histomorphometric digital analysis in the detection of air space over-distension due to pulmonary barotrauma. The study was performed on lung parenchyma specimens of 12 divers: six had died due to arterial gas embolism following pulmonary barotrauma (mean age at death of 54 years, range of 41–61 years), and six had drowned in saltwater without a diagnosis of pulmonary barotrauma (mean age at death of 54 years, range of 41–66 years) (positive controls). For negative controls, six cases of non-SCUBA divers (mean age of death of 42 years, range of 23–55 years) who died of intracerebral haemorrhage were evaluated. No significant differences were observed in the characteristics of the air spaces between control groups (positive and negative). However, differences were observed in the area occupied by air spaces and the percentage of air space area when we compared the case group to the controls (p < 0.01); and there was a slight difference in the maximum and minimum diameters of air space (p < 0.05). The mean area occupied by air spaces and the mean percentage of air space were the most useful for discriminating pulmonary barotrauma from other causes of death (100% sensitivity and 91.7% specificity). Based on our study, inclusion of an increased pattern of air spaces as a possible diagnostic criterion for pulmonary barotrauma would be useful in discerning the cause of diving death.
Why increase in telework may have affected employee well-being during the COVID-19 pandemic? The role of work and non-work life domains
Authors: Kaltiainen Janne , Hakanen Jari J. 
Published: January 2023

AbstractGiven that millions of employees switched to mandatory telework during COVID-19, and as teleworking practices are likely to continue, it is essential to understand the potential impact of mandatory and non-flexible teleworking practices on employee well-being. Drawing on Conservation of Resources theory, we find support for resource gains as increase in job control mediates the link between increases in teleworking and improvements in well-being (increases in work engagement and decreases in burnout and job boredom). Conversely, the findings indicate resource losses as loss of social support and higher work-non-work interference explain the deterioration in well-being for those whose teleworking increased since the COVID-19 outbreak. By coupling role depletion and role enrichment theories, we find that employees who had children living at home experienced greater work-non-work interference due to increased teleworking. However, having children also buffered the negative impact of work-non-work interference on well-being. The findings are based on a Finnish population sample collected three months before and after the COVID-19 outbreak in March 2020 (N = 996 of matched respondents) and latent change score analyses of within-person changes. Our results provide new insights regarding the potential impact of teleworking on employee well-being in a context where teleworking is not flexible and self-selected by the employees. Notably, our results draw bridges (rather than burn them) between role depletion and enrichment frameworks as having children may simultaneously be “a burden” and “a gift”.
Prediction via Similarity: Biomedical Big Data and the Case of Cancer Models
Authors: Boniolo Fabio , Boniolo Giovanni , Valente Giovanni 
Published: January 2023

AbstractIn recent years, the biomedical field has witnessed the emergence of novel tools and modelling techniques driven by the rise of the so-called Big Data. In this paper, we address the issue of predictability in biomedical Big Data models of cancer patients, with the aim of determining the extent to which computationally driven predictions can be implemented by medical doctors in their clinical practice. We show that for a specific class of approaches, called k-Nearest Neighbour algorithms, the ability to draw predictive inferences relies on a geometrical, or topological, notion of similarity encoded in a well-defined metric, which determines how close the characteristics of distinct patients are on average. We then discuss the conditions under which the relevant models can yield reliable and trustworthy predictive outcomes.
Sources of knowledge in the firm: a review on influential, internal and contextual factors in innovation dynamics
Authors: Pinto Hugo , Guerreiro Jorge André , Fernández-Esquinas Manuel 
Published: January 2023

AbstractThe sources of knowledge are diverse, as each firm interacts with multiple actors in pursuing its mission: partners and strategic allies, suppliers, customers, competitors, specialist organizations such as knowledge-intensive business services, universities, technology centres, public research organizations, innovation intermediaries and public administration bodies. Different kinds of knowledge, both tacit and codified, are relevant for firms. Nevertheless, knowledge needs to be translated into the capacity to act. Hence, knowledge generation and absorption can be understood as two sides of the same coin and it is necessary to take factors that shape both facets into account, in addition to the relationship between the production, transfer and valorisation of knowledge. This article reviews crucial factors for knowledge in firms, aggregated as influential, contextual and internal. Influential factors are associated with knowledge tacitness and the existing knowledge base, whereas the internal characteristics of the firm are also crucial and concern aspects such as the existing innovation culture, leadership attributes and internal research and development capabilities. Finally, contextual factors, such as the territorial dynamics, are essential as environmental enablers for generating and absorbing knowledge. Together, these factors reinforce the dynamic capabilities of the firm and influence the decision to either engage in open innovation strategies or prioritize actions that protect and codify knowledge, thus affecting the firms’ competitiveness.
Prototypical approach for an individualized standardization process in the context of intelligent construction and automation
Authors: Albus Jutta , Hollmann-Schröter Kirsten Elisabeth 
Published: January 2023

AbstractStrategies based on an optimal balance between standardization and individualization must be implemented to successfully overcome the current low level of automation in building construction. Project-specific adaptability can be ensured by a combination of automated machine technology and digital planning tools available today. In addition to achieving economic advantages, the focus is on improving sustainability factors, which concern both material consumption and functionality and improved use of resources and energy for building production and operation. The results of research into “lightweight aerogel concrete technology” has shown that an innovative liquid material mixture with insulating properties can be successfully implemented in an automated production process. An adaptive system for standardized wall, ceiling, and floor panels was developed, which can adapt to specific functionality needs and thus address the requirements of individual building tasks while keeping economic as well as architectural factors in mind. The advanced mono-material complies with current European regulations for insulated wall structures, considering the requirements for load-bearing capacity. Due to its homogeneous insulation effect across the entire element section, the aero lightweight concrete allows for intelligent detailing and connection principles and prevents the formation of thermal bridges. The relationship between material composition, material production, construction method, and building operation is essential for a circular planning process. Robotization as a multiple fabrication technology may facilitate these parameters in one cycle. The new technology allows for the crucial transition from research to an end-to-end construction workflow that maps the entire process chain, from concept planning to design and joining principles up to fabrication and assembly.
Animal sheltering: A scoping literature review grounded in institutional ethnography
Authors: Koralesky Katherine E , Rankin Janet M , Fraser David 
Published: January 2023

AbstractA diverse research literature now exists on the animals, staff and organisations involved in animal sheltering. We reviewed this research through the lens of institutional ethnography, a method of inquiry that focuses on the actual work that people do within institutions. The main topics, identified through a larger ethnographic study of animal sheltering, were: (i) research about shelter staff and officers; (ii) the relinquishment of animals to shelters; and (iii) animals’ length of stay in shelters. After reviewing the literature, we held focus groups with shelter personnel to explore how their work experiences are or are not represented in the research. The review showed that stress caused by performing euthanasia has attracted much research, but the decision-making that leads to euthanasia, which may involve multiple staff and potential conflict, has received little attention. Research on ‘compassion fatigue’ has also tended to focus on euthanasia but a granular description about the practical and emotional work that personnel undertake that generates such fatigue is missing. Published research on both relinquishment and length of stay is dominated by metrics (questionnaires) and often relies upon shelter records, despite their limitations. Less research has examined the actual work processes involved in managing relinquishment as well as monitoring and reducing animals’ length of stay. Institutional ethnography’s focus on people’s work activities can provide a different and more nuanced understanding of what is happening in animal sheltering and how it might better serve the needs of the animals and staff.
Challenges in farmed insect welfare: Beyond the question of sentience
Authors: Barrett Meghan , Fischer Bob 
Published: January 2023

AbstractThe global Insects as Food and Feed (IAFF) industry currently farms over a trillion individual insects a year and is growing rapidly. Intensive animal production systems are known to cause a range of negative affective states in livestock; given the potential scale of the IAFF industry, it is urgent to consider the welfare of the industry’s insect livestock. The majority of the literature on farmed insect welfare has focused on: (i) establishing that insect welfare ought to be of concern; or (ii) extending vertebrate welfare frameworks to insects. However, there are many overlooked challenges to studying insect welfare and applying that knowledge in IAFF industry contexts. Here, we briefly review five of these challenges. We end with practical recommendations for the future study of insect welfare.
Cats just want to have fun: Associations between play and welfare in domestic cats
Authors: Henning Julia , Nielsen Torben , Fernandez Eduardo , Hazel Susan 
Published: January 2023

AbstractPlay is often considered an indicator and promotor of animal welfare and may facilitate closer cat-human relationships. However, few studies have empirically investigated these associations. The current study aimed to investigate play-related factors associated with four welfare outcome measures in cats (Felis catus) including: cat quality of life; cat-guardian relationship quality; problem behaviour prevalence; and behavioural changes. An online survey was developed using demographic information, questions related to play and resources, free text sections and the following validated measures: cat quality of life (QOL), the cat owner relationship scale, and the adult playfulness trait scale. Responses were completed by 1,591 cat guardians from 55 countries. Higher cat playfulness scores and a greater number of games played were significantly associated with higher cat QOL scores while longer amounts of daily play, greater number of games, both cat and guardian initiating play and higher guardian playfulness scores were all significantly associated with higher cat-guardian relationship scores. Exclusively indoor housing was significantly associated with both higher cat QOL and higher cat-guardian relationships scores compared to cats with outdoor access. Behavioural changes associated with distress in cats were reported when play was absent. Play may be an important factor in assessing and maintaining cat welfare. Further research into the mechanisms of how play impacts welfare and cat-guardian relationships is needed.