bluuebunny/crossref_metadata_2025_split huggingface dataset:
EFFICACY AND SAFETY OF APREMILAST IN MODERATE TO SEVERE CASES OF CHRONIC PLAQUE PSORIASIS: A RETROSPECTIVE STUDY
Authors: KHAN S , FAROOQ M , TARIQ F , AHMED R , ASLAM MA 
Published: January 2023

The objective of this study was to assess the efficacy and safety of Apremilast in patients with moderate-to-severe plaque psoriasis. A retrospective study was conducted in the Dermatology Department of Bakhtawar Amin Trust Hospital Multan from September 2021 to September 2022. A total of 102 patients were included in the study after evaluation. Apremilast was administered in all the patients, and its clinical response was assessed by the extent of Psoriasis Area Severity Index (PASI) reduction 16 weeks after the start of treatment. Our secondary endpoints included examining the PASI; Dermatology Life Quality Index (DLQI); Physician Global Assessment (PGA); the adverse effects of treatment; survival rate; reasons for discontinuation of treatment, if any, and the rate of patients who managed to reach Psoriasis Area Severity Index reduction up to 50%, 75%, 90% and 100% after 16 weeks. 37 (72.5%) subjects achieved PASI reduction ≥75% or ≥50%, thus achieving the primary endpoint. The majority of the study sample had moderate psoriasis, with a mean baseline DLQI score of 11.2, PASI score of 11.0 and PGA score 2.6. After 16 weeks, 65% subjects had PGA score ≤1. PASI improved rapidly over 4 (4.8) (P<.001) to 16 weeks (4.3) (P<.001). DLQI at baseline was 11.2; after 16 weeks, it was 3.8 (P<.001). Regarding secondary endpoints, after 16 weeks, 35/37 (94.5%) subjects achieved ΔPASI≥50, 18/37 (48.6%) ΔPASI≥75, 8/37 (21.6%) achieved ΔPASI≥90 and 6/37(16.2%) achieved ΔPASI100. Treatment-related adverse effects occurred in 16/51 (31.3%) patients. In total, treatment was stopped in 6 (11.6%)subjects because of adverse effects; gastrointestinal disorders were the most common. Apremilast is an effective and safe drug for the treatment of patients with moderate-to-severe plaque psoriasis.
Touch – Feel – Experience – Consider
Authors: Anna Raczek-Karcz Marta 
Published: January 2023

The last two decades have brought a visible and perceptible change in artistic printmaking practices. Besides traditional forms of presentation, i.e., framed or unframed print on paper or any other surface, we may observe new ways of interacting with viewers, who become more and more involved in transforming themselves into active participants or even co-producers of the artistic project. This paper focuses on such artistic proposals, and if more classical artworks are mentioned, the reason is their non-traditional aspects like provocative visual play with viewers’ perceptions.
Those formal aspects of analysed artistic examples are linked to the ideas expressed by the artists in question, which revolve around different crises and catastrophes that humanity is facing today. The leitmotiv of the general approach represented by Sean Caulfield, Karol Pomykała or Angela Snieder is related to the postulate posed by Jean-Luc Nancy (2015, p. 8), that:
"We are being exposed to a catastrophe of meaning. Let’s not hurry to hide this exposure under pink, blue, red, or black silks. Let us remain exposed, and let us think about what is happening [ce qui nous arrive] to us: Let us think that it is we who are arriving, or who are leaving."
We Are in Record. The Temporality of Print/Making
Authors: Fitzhugh Annis 
Published: January 2023

"This is the Time. And this is the record of the time. This is the Time. And this is the record of the time."
Laurie Anderson
In 2014, Stedelijk Museum Bureau Amsterdam took these lyrics of Laurie Anderson’s as a cue for an exhibition by artists investigating ‘to what extent the recording mechanisms and material recordings of our lived times represent and influence our perception of temporality’ (Harutyunyan and Muller, 2016, p17).
A later publication includes articles from a linked conference in Beirut, Thinking About Time that, like the artworks, ‘shares an endeavor to make time an object of thought without objectifying it.’ (Harutyunyan, 2016, p23)
It was when considering the texts in this publication that I started to reflect on print as just such a material recording. None of the essays, though wide-ranging, considers printmaking, provoking me to map the arguments onto print for myself, particularly in the light of recent collaborations with artists Alberta Whittle, Rae-Yen Song, and Annalee Davis, all of whom make work directly referencing distances of time and geography.
Descripción de una nueva especie de Hybreoleptops Kuschel, 1949 y comentarios sobre otros representantes del género (Insecta: Coleoptera: Curculionidae)
Authors: Elgueta Mario 
Published: January 2023

Se describe Hybreoleptops roseus n. sp., propia de ambientes boscosos de la costa de Chile central, entre los 34°10'S y 36°10'S. Esta especie se encuentra en alturas de 200 a 450 metros sobre el mar; sus adultos se asocian al follaje de diversos árboles y arbustos, presentes en esa franja altitudinal.
Basado en el estudio del material tipo, se propone la sinonimia: Hybreoleptops santiagensis Pérez y Posadas, 2006 = Hybreoleptops juanjosei Pérez y Posadas, 2006; con prioridad de página del primer nombre, sobre el segundo.
Se efectúan comentarios sobre el género Hybreoleptops, se detallan los vegetales a los cuales se asocian los adultos de las especies conocidas y se entrega una clave para el reconocimiento de las especies.
Se confirma la presencia de Hybreoleptops vestitus (Blanchard) en la provincia de Neuquén, Argentina.
pecie.
Conservación de las Colecciones Bioantropológicas del Museo Nacional de Historia Natural (Santiago, Chile)
Authors: Acevedo C. Nieves 
Published: January 2023

El objetivo del presente trabajo es dar a conocer el sistema de conservación de las colecciones bioantropológicas del Museo Nacional de Historia Natural, que se viene aplicando desde la década de los años 80.
Este trabajo presenta una síntesis de cómo se formó la colección que hoy resguarda dicho Museo, su incremento a través del tiempo y su actual estado, abordando aspectos tales como origen, adquisición y conservación.
Sobre la base de esta experiencia se plantean proposiciones y sugerencias que apuntan a un manejo integral de estas colecciones desde una perspectiva museológica.
Revisión del estatus taxonómico de Liolaemus Donosoi Ortiz, 1975 (Iguania: Liolaemidae)
Authors: Troncoso-Palacios Jaime 
Published: January 2023

Liolaemus donosoi, es una especie con una compleja historia taxonómica. La descripción original carece de comparaciones con especies relacionadas y los posteriores trabajos han propuesto que a) es indistinguible de L. constanzae, b) que es una subespecie de ésta, o c) que es una especie plena.
Aquí se analiza su historia taxonómica y caracteres morfológicos, concluyéndose que L. donosoi es un sinónimo menor de L. constanzae.
Biotopos marinos intermareales y submareales (Crucero Cimar 16 fiordos) desde el Estrecho de Magallanes al Canal Beagle
Authors: Letelier Sergio , Báez Pedro , Ramírez María E. , Rebolledo Andrea , Soto Eulogio , Naretto Javier 
Published: January 2023

Durante el Crucero 16 CIMAR Fiordos realizado entre el Estrecho de Magallanes y el Canal Beagle (53º11,16'S; 73º24,06'W-55º09'03,92''S, 68º08'27,9''W) se realizó un muestreo intermareal y submareal de 14 estaciones. Estas muestras se obtuvieron manualmente y por buceo apnea, en transectas perpendiculares a la línea de la costa, con orientación sur-este y en ellas se aplicó la metodología establecida en el Crucero CIMAR 15 para la caracterización de los biotopos costeros.
Se determinaron 10 biotopos marinos que corresponden a tres grandes grupos:
1) biotopos con fuerte influencia de agua dulce de deshielos y lluvias, con playas extensas sin pendientes rocosas; son de diversidad baja, con presencia notoria de Porphyra spp. en sectores rocosos planos y con salinidades que varían entre 1 y 20‰;
2) biotopos rocosos con mayor pendiente, comparativamente con mayor influencia de mareas y presencia de algas rodófi tas, feófitas y clorófi tas asociadas a bivalvos, gasterópodos, cirripedios y otros invertebrados, y con salinidad de 24 a 28‰; y
3) submareales someros, desde 1 hasta 16,4 m de profundidad, caracterizados principalmente por la presencia de feóficeas, Macrocystis pyrifera principalmente, asociadas con moluscos, crustáceos, poliquetos y equinodermos, y con salinidades entre 32 y 35‰.
Se observaron coincidencias con los biotopos descritos para el sector del Parque Nacional Laguna San Rafael, estero Elefantes, archipiélago de los Chonos, y tres biotopos mencionados para los canales Trinidad y Smyth, al norte del Estrecho de Magallanes.
Cymatoceras perstriatum (Steuer 1897) (Cephalopoda, Nautiloidea) del Berriasiano Temprano - Valanginiano Temprano (Cretácico Inferior) de Chile central
Authors: Salazar Christian , Martínez Alejandro , Villanelo Luciano , Stinnesbeck Wolfgang 
Published: January 2023

El nautílido Cymatoceras perstriatum fue originalmente registrado por Steuer para el Titoniano de la provincia de Mendoza en Argentina Central. Estudios posteriores registraron este taxón en rocas sedimentarias del Valanginiano - Barremiano en la provincia de Neuquén de Argentina. Cymatoceras cf. perstriatum también fue documentado para el Barremiano tardío de la región de Atacama de Chile. En Chile central Klohn lista Cymatoceras cf. Perstriatum para el Berriasiano Temprano - Valanginiano Temprano. Aquí, se revisa el único espécimen mencionado por Klohn y discute su proveniencia y rango estratigráfico. Nosotros concluimos que el espécimen recolectado por Klohn proveniente del Berriasiano Temprano al Valanginiano Temprano, son rocas sedimentarias de la Formación Lo Valdés y que este es el registro más antiguo en Chile. El taxón aparentemente es endémico de la Cuenca Andina.
UNA REVISTA PARA LA REGIÓN HUANCAVELICA Y EL MUNDO: OECONOMICUS UNH
Authors: Ramos Serrano Rúsbel Freddy 
Published: January 2023

La Universidad Nacional de Huancavelica (UNH) es una institución representativa de la región central del país, y en su esencia es “…una comunidad académica del más alto nivel orientada a la investigación y a la docencia que brinda una formación humanística, científica, tecnológica e innovadora con responsabilidad social y consciente de la realidad nacional multicultural.” En este sentido, a través de sus Facultades, Escuelas Profesionales y diversas unidades busca la generación de desarrollo, apostando por la ciencia, el conocimiento, la tecnología, la cultura mediante actividades de extensión y proyección hacia nuestras comunidades.
Así, nuestra querida UNH preocupada por satisfacer la creciente demanda de información de calidad y atención a nuestros hermanos huancavelicanos y peruanos, pone sus recursos disponibles y capital humano a disposición del país, ofreciendo sus habilidades y competencias para el logro de objetivos concretos locales, regionales y nacionales. En este escenario, la generación y difusión de conocimiento es de vital importancia para lograr tal fil. Con esta consigna, compartimos con nuestro país y el mundo las investigaciones que nuestros investigadores van desarrollando en sus diferentes manifestaciones y ofrecemos al lector un panorama importante que nace desde la región central del país.
Finalmente, este compromiso es posible gracias al apoyo y respaldo institucional como por aquellas personas que están detrás de las letras que se verterán en las próximas páginas. Sin duda nuestro reconocimiento y aprecio sempiterno para todos aquellos que hacen posible Oeconomicus UNH.
AN OVERVIEW OF IATROGENIC OBESITY IN ADOLESCENTS
Authors: ALSUDAIRY NAJLAA MOHAMMAD , ALQAHTANI OHUD MOHAMMED , ALAJMI MOUDHI MOHAMMED , ALRADADI SAUD SAAD , ALRSHODY ABDULRAHMAN MOHAMMED , JAMALUDDIN HUSSAM ABDULSHAKOUR , ALRAQIBAH SULAIMAN ABDULLAH , ALRETHAIA ABDULAZIZ HOMOUD A. , ALSULAMI SAEED FARAJ , ALDEHAMI MARYAM ABDULRAHMAN , ALSHOMRANI ABDULLAH ALI , ALSHANQITI MOHAMMED ALHUSSAIN , ALOWAYDHAH BASSAM MOHAMMAD , ALZAAQ RENAD BRAHIM SALEH 
Published: January 2023

Obesity is a chronic, multifactorial condition described as an abnormal or excessive buildup of body fat that endangers an individual's health. It is a huge global public health problem. Prednisone and anti-psychotic medicines are known to cause weight gain and obesity. In this era of precision medicine, it is critical to identify individuals who are most likely to gain weight as a result of pharmaceutical use. Hypoglycemic anti-diabetes medicines, psychotropic agents (atypical antipsychotics, antidepressants), anticonvulsant and mood stabilizer agents, and different hormones are the most regularly reported prescription groups that may cause weight gain. The obesity pandemic is multifaceted, but medication-induced weight gain may play a role. While doctors may aim to pick pharmacotherapies with the least detrimental influence on weight, the literature on the weight effects of medicine is frequently inadequate and empty of alternative treatments. Because of the devastating consequences of adolescents obesity, new therapies are desperately needed. Real-world data reveal that the majority of teenagers do not lose weight over time, and pharmacological therapy should be recommended.
DEVELOPMENT OF AUDIO-VISUAL MEDIA IN LISTENING LEARNING FOR GRADE IV ELEMENTARY SCHOOL STUDENTS
Authors: Pradina Nadya Putri 
Published: January 2023

Abstract
This study aims to produce an audio-visual learning media product that is useful in listening learning for fourth grade elementary school students. And to determine the feasibility of the audio-visual media that the researchers have developed. This study uses the Research and Development (R&D) method and using the Four-D model research stage (Define, Design, Develop, Disseminate). Validation is carried out by expert validators and practitioner validators. Product trials were carried out in stages, namely stage 1 and stage 2. The results showed that the validation of design experts obtained an assessment with a very valid category. In validation linguists obtained assessment with a very valid category. In the validation of the material experts, they obtained an assessment with a very valid category. And the validation of the material by the practitioner validator obtained an assessment with a very valid category. The students written test in the form of objective questions received an assessment with a very good category. The results of the questionnaire responses from students and teachers obtained an assessment with a very practical category. So, the results of this study indicate that development of audio-visual media in listening learning is very suitable for use for fourth grade elementary school students.
Keyword: Audio Visual Media, Listening
Child marriage in the light of objectives of Shari’ah and Islamic jurisprudence (An Analytical study of prevalent practices in Pakistani Society)
Authors: Khan Amrina , Iqbal Asim 
Published: January 2023

Islam envisages marriage as a source of productivity and prosperity for mankind. This is a legal contract between two mature persons, thus it must be in harmony with the objectives of Islamic Shari’ah namely the protection of lineage and protection of honour. Marriage as a pivotal part of an Islamic society must fulfill the before-mentioned objectives of Shari’ah. Among other concerns regarding the matter of marriage, one of the important is the issue of child marriage. Keeping that in view, this study has analyzed whether child marriage fulfills these objectives or not or at what cost. Further, this study has figured out the opinions of four jurists of Islam regarding the issue at hand and has provided a synthesized solution. This research has also delved into highlighting the possible factors leading to child marriage in Pakistani society, and the pros and cons of child marriage. The descriptive and analytical methodology has been used in this study. Moreover, suggestions are put forth to deal with the primary concerns of child marriage in the light of Islamic Sharia’.
A alimentação escolar e as compras locais da agricultura familiar: uma análise bibliométrica da literatura
Authors: Da Silva Joelma Melo , Pantoja Maria Júlia , Delgrossi Mauro Eduardo 
Published: January 2023

Objetivo­ – Revisar a literatura atual sobre a qualidade da alimentação escolar e as compras locais da agricultura familiar, na tentativa de identificar clusters de pesquisadores e apontar necessidades de pesquisas nessa temática.Design – Pesquisa exploratória e descritiva, caracterizada como estudo bibliométrico, com abordagem quantitativa. Utilizando o software CiteSpace versão 5.7.R2, analisou-se 2.042 artigos recuperados da Web of Science. Os resultados foram discutidos à luz da literatura.Análise – Analisou-se a rede de co-citation. Resultados – Por mais de dez anos o cluster “Competitive Food” agrupou o maior número de pesquisadores. Os clusters mais recentes estavam focados na qualidade nutricional da alimentação escolar. O cluster “COMPASS Study” indicou que pesquisadores focalizam estudos longitudinais como possibilidade de integrar pesquisa, avaliação, política e prática preventiva que visem melhorar a saúde dos alunos. O cluster “Rio Grande” indicou que o Brasil demostra maior interesse em relacionar os temas abordados nesta pesquisa. Conclusões e implicações – A centralidade da dimensão nutricional para a qualidade alimentar está sendo deslocada para outros aspectos, tais como, sentimentos do aluno em relação à escola, à comunidade e, o bullying. Dessa forma, a tendência é que os estudos sejam mais abrangentes e as políticas mais inclusivas. No entanto, a contribuição das compras locais da agricultura familiar para a qualidade da alimentação escolar carece ser mais explorada.
Comparative Study of Culture of Entrepreneurship and Financial Culture in Micro and Small Entrepreneurs of Trujillo, Peru
Authors: Tello Asunción Ramón Lezcano 
Published: January 2023

The present research decided to formulate as a general objective "To determine and compare the levels of Entrepreneurship Culture and Financial Culture in Micro and Small Entrepreneurs in Trujillo, Peru 2022". It was observed that micro and small entrepreneurs face a big problem when applying for loans from banks and financial institutions based in Trujillo, limiting their possibilities to apply for financing. For these reasons, the research aims to improve this problematic reality. In this research situation is that we formulated the following question: ¿What are the comparative levels of Entrepreneurship Culture and Financial Culture in Micro and Small entrepreneurs in Trujillo, Peru 2022? We developed a quantitative approach, with a non-experimental design, cross-sectional, applied type, with a causal correlational level, the technique considered was the survey and the instrument was the questionnaire, which was applied to 38 micro and small entrepreneurs in the city of Trujillo. The results showed that there is a high level of correlation between Entrepreneurship Culture and "Financial Culture" according to the dimension of obtaining capital, with a Spearman's Rho of 1, demonstrating that the more risk acceptance, leadership, creativity, and innovation are positively improved, the more the obtaining of capital is favored through improvements in financial knowledge.
Computer Programming Language Solution to a Transportation Problem Involving a Concave Cost Function
Authors: Jude Opara , Akpofure Ojekudo, Nathaniel 
Published: January 2023

The work is on computer programming language solution to a transportation problem involving a concave cost function. Two computer programming languages; Wolfram Mathematica and Anaconda Python programming tools were employed in this study to effectively solve four real life examples from published works. The results from the programming languages yielded an optimal value of N253,000 with an optimal solution as z12 = 13, z22 = 5, z23 = 8, z31 = 11 and z33 = 4 in the first example and the remaining three examples were successfully solved with optimal values of N377,000, GH¢ 236,000 and N509,000 respectively, and the results agreed with the results of existing Karush-Kuhn-Tucker (KKT) procedure of Modified Distribution Method.
Short Term Outcome of Percutaneous Coronary Intervention in Anaemic Patients Presenting with Coronary Artery Diseases
Authors: El Saiyed Moaz Emad El Din , Nassar Mohamed Bayoumi , Gendy Ehab Abd El Lateif El , Badr Seham Fahmy 
Published: January 2023

Background: Percutaneous coronary intervention (PCI) has been an effective and widely used treatment for patients with coronary artery disease (CAD). The presence of anaemia in critically ill patients undergoing surgical procedures has been associated with worse clinical outcomes.
Hence, the current study was conducted to assess short term outcome of percutaneous coronary interventions in anaemic patients presenting with coronary artery diseases.
Methods: This prospective observational study enrolled 200 patients who underwent PCI. Patients were classified into 2 groups: anaemic patients and non-anaemic patients. The anaemic patients were furtherly be classified according to severity of anaemia into 3 grades mild anaemia, moderate anaemia, and severe anaemia.
All cases were subjected to complete history taking, clinical examination and baseline laboratory tests: including CBC, serum urea and creatinine, cardiac enzymes include serum troponin, CK-MB and standard 12-lead ECG.
Results: The mean Heart Rate was statistically significantly higher in the anaemic group as compared with the non-anaemic group. The mean Ejection Fraction was statistically significantly lower in the anaemic group as compared with the non-anaemic group. The percentage of LM affection in the anaemic group was statistically significantly higher as compared with the non-anaemic group. The incidence of arrythmia in the anaemic group was statistically significantly higher as compared with the non-anaemic group. Severe anaemic and low EF% patients were associated with higher incidence of stroke and MI.
Conclusions: Patients with baseline anaemia before PCI have a higher incidence of PCI associated complications. Therefore, anaemia could be a predictor of PCI related complications.
Bioassay on Toxicity of Plant Extracts against Aphis craccivora Koch (Hemiptera: Aphididae) in French Bean (Phaseolus vulgaris L.)
Authors: Kichu Nokchensaba , Imtinaro L. , Neog Pankaj , Ozukum Limasunep 
Published: January 2023

The present experimental study was conducted under laboratory conditions in the department of Entomology, School of Agricultural Sciences and Rural Development, Nagaland University, Medziphema Campus during 2017 to 2018. For bioassay on the toxicity of plant extract on Aphids (Aphis craccivora Koch) in French beans, five botanicals were used namely, Neem (Azadirachta indica), Datura (Datura stramonium), Lantana (Lantana camara), Nigeria Eucalyptus (Eucalyptus globules) and Citronella (Cymbopogon winterianus) with one chemical i.e. Dimethoate 30 EC and control. The laboratory bioassay was done using dipping method and the LC 50 values were calculated using Probit analysis. The results from the Probit analysis at 24, 48 and 72 hours showed that the standard check Dimethoate 30 EC was the most toxic @ 0.01%. For botanicals, L. camara and A. indica extract @ 3% concentration, reported the highest mortality followed by D. stramonium extract @ 4%. In comparision E. globules and C. winterianus @ 5% reported the lowest mortality. Based on the study the order of toxicity of plant products based on Probit analysis are A. indica > L. camera > D. stramonium > C. winterianus > E. globules.