bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of dynamic shading control for daylight measures in green buildings towards overall energy efficiency of lighting and air-conditioning systems
Authors: Sun Jingting 
Published: September 2023

AbstractThe introduction of daylight can improve buildings’ energy efficiency and bring benefit to occupant satisfaction. However, the introduction of daylight may accompany with excessive heat. Properly counterbalancing the energy consumption of air conditioning and lighting systems owing to the entry of daylight is a critical control target of dynamic shading adjustment in cooling season. Most dynamic shading control strategies in use only consider one single system. Additionally, for advanced control mode like performance-based control, the predictive model usually only examines the instantaneous effect of energy performance to determine the shading adjustment state, unable to quantify the overall influence of shading adjustment state on building energy consumption. In order to address this issue, special consideration is given to calculating the cumulative contribution of heat gains to cooling load in this study. An overall energy-efficient shading control metric is proposed and used as basis to develop optimized dynamic shading control strategy. An application example demonstrates that the SGR-Optimal control strategy can further save energy by 21.8% ~ 38.8% when compared to the Rule-based control strategy, thus allowing a better exploration of the energy efficiency potential of daylight measure.
The Literary Criticism of Samuel Johnson
Authors: Smallwood Philip 
Published: September 2023

For Samuel Johnson, poetical judgments were no mere exercise in dry evaluation; rather, they reflected deep emotional responsiveness. In this provocative study, Philip Smallwood argues for experiencing Johnson's critical texts as artworks in their own right. The criticism, he suggests, often springs from emotional sources of great personal intensity and depth, inspiring translation of criticism into poetry and channelling prose's poetic potential. Through consideration of other critics, Smallwood highlights singularities in Johnson's judgments and approach, showing how such judgments are irreducible to philosophical doctrines. 'Ideas', otherwise the material of criticism's propensity to systems and theories, exist for Johnson as feelings that 'slumber in the heart.' Revealing Johnson's humour and intellectual reach, Smallwood frames his criticism in unresolved ironies of time and forms of historical change. This title is part of the Flip it Open Programme and may also be available Open Access. Check our website Cambridge Core for details.
Stewardship 2.0: Embracing elements of implementation science to enhance everyday antimicrobial Stewardship efforts
Authors: Monsees Elizabeth , Wirtz Ann L. , Krein Sarah 
Published: September 2023

Abstract
This article explores the utility of implementation science (IS) as a method to promote the effective uptake of antimicrobial stewardship processes. Elements of IS can be readily incorporated into QI work and used as a platform to extend stewardship reach. As stewards are stretched to do more, IS can be a potential vehicle to ensure that our collective work is impactful, sustainable, and contributes more broadly to clinically relevant improvements.
Experiences of a mobile phone delivered brief intervention for hazardous drinking: A qualitative study nested in the AMBIT trial from Goa, India
Authors: Fernandes Danielle , D’Souza Ethel , Sambari Seema , Pacheco Marimilha , D’Souza Joseline , Velleman Richard , Bhatia Urvita , Nadkarni Abhijit 
Published: September 2023

Abstract

Background
This study explores the experiences of participants receiving a mobile-based brief intervention (BI) for hazardous drinking in India, to determine characteristics that influenced engagement and examine perceived reasons for change in alcohol consumption.

Methods
Semi-structured interviews were conducted with 10 adult hazardous drinkers who received a mobile-based BI in the intervention arm of a pilot randomised control trial. Data were coded through an iterative process and analysed using thematic analysis.

Findings
Study participants reported a positive experience, with factors such as customised intervention delivery and personal motivation facilitating their engagement. Participants reported a reduction in quantity and frequency of alcohol use. This was credited to the intervention, particularly, its provision of health-related information, goal-setting content and strategies to manage drinking. Apart from alcohol reduction, participants reported improvements in diet, lifestyle, wellbeing, and familial relations.

Implication
By providing a context to explain the impact of the intervention, the learnings from this study can be used to strengthen the implementation of mobile-based interventions. This study outlines the scope for further research in digital health, such as Internet-based health interventions, and incorporating digital interventions within the ambit of existing health care programmes.
USUBA’S PRINCIPLE CAN FAIL AT SINGULAR CARDINALS
Authors: GOLSHANI MOHAMMAD , SHELAH SAHARON 
Published: September 2023

AbstractWe answer a question of Usuba by showing that the combinatorial principle
$\mathrm {UB}_\lambda $
can fail at a singular cardinal. Furthermore,
$\lambda $
can be taken to be
$\aleph _\omega .$
Viable Clostridium botulinum spores not detected in the household dust of major Canadian cities
Authors: Harris Richard A. , Blondin-Brosseau Madeleine , Levesque Christine , Rasmussen Pat E. , Beauchemin Suzanne , Austin John W. 
Published: September 2023

Abstract
Clostridium botulinum causes infant botulism by colonising the intestines and producing botulinum neurotoxin in situ. Previous reports have linked infant botulism cases to C. botulinum spores in household dust, yet the baseline incidence of C. botulinum spores in residential households is currently unknown. Vacuum cleaner dust from 963 households in 13 major Canadian cities was tested for C. botulinum using a novel real-time PCR assay directed against all known subtypes of the botulinum neurotoxin gene. None of the samples tested positive for C. botulinum. Analysis of a random subset of samples by MALDI Biotyper revealed that the most common anaerobic bacterial isolates were of the genus Clostridium and the most common species recovered overall was Clostridium perfringens. Dust that was spiked with C. botulinum spores of each toxin type successfully produced positive real-time PCR reactions. These control experiments indicate that this is a viable method for the detection of C. botulinum spores in household dust. We make several recommendations for future work that may help discover a common environmental source of C. botulinum spores that could lead to effective preventative measures for this rare but deadly childhood disease.
Comparison of serum N-terminal pro-brain natriuretic peptide levels, conventional echocardiography, exercise parameters, and dyssynchrony measurements in Fontan patients
Authors: Cindik Nimet , Gökdemir Mahmut , Varan Birgül , Ulubay Gaye , Ozkan Murat , Tokel Niyazi Kürşad 
Published: September 2023

AbstractIntroduction:Little data are available concerning the methods used in the long-term follow-up of Fontan patients. We analyzed the association between serum N-terminal pro-brain natriuretic peptide levels, conventional echocardiography findings, exercise parameters, and dyssynchrony measurements in patients who underwent Fontan surgery.Methods:This study included 28 patients who underwent Fontan surgery (mean age 12.8 ± 4.36 years) and 27 healthy controls (mean age 12.5 ± 3.76 years). Echocardiography examinations and exercise tests were performed in both groups. The systemic ventricle was examined via echocardiography, dyssynchrony measurement was performed, the systemic ventricular myocardial performance index was calculated, and serum N-terminal pro-brain natriuretic peptide levels were measured for all subjects.Results:Lower cardiac output, stroke volume, maximal work, chronotropic index, maximal oxygen uptake, and higher N-terminal pro-brain natriuretic peptide levels were observed in the Fontan group than in the control group (p < 0.05). A negative correlation was found between physical exercise parameters and N-terminal pro-brain natriuretic peptide levels and dyssynchrony measurements.Conclusion:Measurements of exercise capacity, serum N-terminal pro-brain natriuretic peptide levels, and dyssynchrony measurement were more valuable than conventional methods for assessing patients’ clinical and functional status. Dyssynchrony measurements provided better information about ventricular status than did conventional echocardiography studies. While patients’ systolic function determined by conventional echocardiography was normal, dyssynchrony measurements showed the opposite result. The negative relationship between serum N-terminal pro-brain natriuretic peptide levels, dyssynchrony measurements, and exercise capacity suggests that these parameters should be investigated further in Fontan patients.
Ethical Decision Making in Disaster and Emergency Management: A Systematic Review of the Literature
Authors: Cuthbertson Joe , Penney Greg 
Published: September 2023

AbstractEthical decision making in disaster and emergency management requires more than good intentions; it also asks for careful consideration and an explicit, systematic approach. The decisions made by leaders and the effects they have in a disaster must carry the confidence of the community to which they serve. Such decisions are critical in settings where resources are scarce; when decisions are perceived as unjust, the consequences may erode public trust, result in moral injury to staff, and cause community division. To understand how decisions in these settings are informed by ethics, a systematic literature review was conducted to determine what ethical guidance informs decision making in disaster and emergency management. This study found evidence of ethical guidance to inform decision making in disaster management in the humanitarian system, based on humanitarian principles. Evidence of the application of an ethical framework to guide or reference decision making was varied or absent in other emergency management agencies or systems. Development and validation of ethical frameworks to support decision making in disaster management practice is recommended.
Flood Impacts on Net Ecosystem Exchange in the Midwestern and Southern United States in 2019
Authors: Balashov Nikolay V. , Ott Lesley E. , Weir Brad , Basu Sourish , Davis Kenneth J. , Miles Natasha L. , Thompson Anne M. , Stauffer Ryan M. 
Published: September 2023

AbstractClimate extremes such as droughts, floods, heatwaves, frosts, and windstorms add considerable variability to the global year‐to‐year increase in atmospheric CO2 through their influence on terrestrial ecosystems. While the impact of droughts on terrestrial ecosystems has received considerable attention, the response to flooding is not well understood. To improve upon this knowledge, the impact of the 2019 anomalously wet conditions over the Midwest and Southern US on CO2 vegetation fluxes is examined in the context of 2017–2018 when such precipitation anomalies were not observed. CO2 is simulated with NASA's Global Earth Observing System (GEOS) combined with the Low‐order Flux Inversion, where fluxes of CO2 are estimated using a suite of remote sensing measurements including greenness, night lights, and fire radiative power as well as with a bias correction based on insitu observations. Net ecosystem exchange CO2 tracers are separated into the three regions covering the Midwest, South, and Eastern Texas and adjusted to match CO2 observations from towers located in Iowa, Mississippi, and Texas. Results indicate that for the Midwestern region consisting primarily of corn and soybeans crops, flooding contributes to a 15%–25% reduction of annual net carbon uptake in 2019 in comparison to 2017 and 2018. These results are supported by independent reports of changes in agricultural activity. For the Southern region, comprised mainly of non‐crop vegetation, annual net carbon uptake is enhanced in 2019 by about 10%–20% in comparison to 2017 and 2018. These outcomes show the heterogeneity in effects that excess wetness can bring to diverse ecosystems.
Lysosomes mediate the mitochondrial UPR via mTORC1-dependent ATF4 phosphorylation
Authors: Li Terytty Yang , Wang Qi , Gao Arwen W. , Li Xiaoxu , Sun Yu , Mottis Adrienne , Shong Minho , Auwerx Johan 
Published: September 2023

AbstractLysosomes are central platforms for not only the degradation of macromolecules but also the integration of multiple signaling pathways. However, whether and how lysosomes mediate the mitochondrial stress response (MSR) remain largely unknown. Here, we demonstrate that lysosomal acidification via the vacuolar H+-ATPase (v-ATPase) is essential for the transcriptional activation of the mitochondrial unfolded protein response (UPRmt). Mitochondrial stress stimulates v-ATPase-mediated lysosomal activation of the mechanistic target of rapamycin complex 1 (mTORC1), which then directly phosphorylates the MSR transcription factor, activating transcription factor 4 (ATF4). Disruption of mTORC1-dependent ATF4 phosphorylation blocks the UPRmt, but not other similar stress responses, such as the UPRER. Finally, ATF4 phosphorylation downstream of the v-ATPase/mTORC1 signaling is indispensable for sustaining mitochondrial redox homeostasis and protecting cells from ROS-associated cell death upon mitochondrial stress. Thus, v-ATPase/mTORC1-mediated ATF4 phosphorylation via lysosomes links mitochondrial stress to UPRmt activation and mitochondrial function resilience.
Strategy to combat biofilms: a focus on biofilm dispersal enzymes
Authors: Wang Shaochi , Zhao Yanteng , Breslawec Alexandra P. , Liang Tingting , Deng Zhifen , Kuperman Laura L. , Yu Qiuning 
Published: September 2023

AbstractBacterial biofilms, which consist of three-dimensional extracellular polymeric substance (EPS), not only function as signaling networks, provide nutritional support, and facilitate surface adhesion, but also serve as a protective shield for the residing bacterial inhabitants against external stress, such as antibiotics, antimicrobials, and host immune responses. Biofilm-associated infections account for 65-80% of all human microbial infections that lead to serious mortality and morbidity. Tremendous effort has been spent to address the problem by developing biofilm-dispersing agents to discharge colonized microbial cells to a more vulnerable planktonic state. Here, we discuss the recent progress of enzymatic eradicating strategies against medical biofilms, with a focus on dispersal mechanisms. Particularly, we review three enzyme classes that have been extensively investigated, namely glycoside hydrolases, proteases, and deoxyribonucleases.
Updates to the NASA human system risk management process for space exploration
Authors: Antonsen Erik L. , Connell Erin , Anton Wilma , Reynolds Robert J. , Buckland Daniel M. , Van Baalen Mary 
Published: September 2023

AbstractThis paper describes updates to NASA’s approach for assessing and mitigating spaceflight-induced risks to human health and performance. This approach continues to evolve to meet dynamically changing risk environments: lunar missions are currently being designed and the ultimate destination will be Mars. Understanding the risks that astronauts will face during a Mars mission will depend on building an evidence base that informs not only how the humans respond to the challenges of the spaceflight environment, but also how systems and vehicles can be designed to support human capabilities and limitations. This publication documents updates to the risk management process used by the Human System Risk Board at NASA and includes changes to the likelihood and consequence matrix used by the board, the design reference mission categories and parameters, and the standardized evaluation of the levels of evidence that the board accepts when setting risk posture. Causal diagramming, using directed acyclic graphs, provides all stakeholders with the current understanding of how each risk proceeds from a spaceflight hazard to a mission-level outcome. This standardized approach enables improved communication among stakeholders and delineates how and where more knowledge can improve perspective of human system risks and which countermeasures can best mitigate these risks.
Protein remote homology detection and structural alignment using deep learning
Authors: Hamamsy Tymor , Morton James T. , Blackwell Robert , Berenberg Daniel , Carriero Nicholas , Gligorijevic Vladimir , Strauss Charlie E. M. , Leman Julia Koehler , Cho Kyunghyun , Bonneau Richard 
Published: September 2023

AbstractExploiting sequence–structure–function relationships in biotechnology requires improved methods for aligning proteins that have low sequence similarity to previously annotated proteins. We develop two deep learning methods to address this gap, TM-Vec and DeepBLAST. TM-Vec allows searching for structure–structure similarities in large sequence databases. It is trained to accurately predict TM-scores as a metric of structural similarity directly from sequence pairs without the need for intermediate computation or solution of structures. Once structurally similar proteins have been identified, DeepBLAST can structurally align proteins using only sequence information by identifying structurally homologous regions between proteins. It outperforms traditional sequence alignment methods and performs similarly to structure-based alignment methods. We show the merits of TM-Vec and DeepBLAST on a variety of datasets, including better identification of remotely homologous proteins compared with state-of-the-art sequence alignment and structure prediction methods.
Multi-omics data integration using ratio-based quantitative profiling with Quartet reference materials
Authors: Zheng Yuanting , Liu Yaqing , Yang Jingcheng , Dong Lianhua , Zhang Rui , Tian Sha , Yu Ying , Ren Luyao , Hou Wanwan , Zhu Feng , Mai Yuanbang , Han Jinxiong , Zhang Lijun , Jiang Hui , Lin Ling , Lou Jingwei , Li Ruiqiang , Lin Jingchao , Liu Huafen , Kong Ziqing , Wang Depeng , Dai Fangping , Bao Ding , Cao Zehui , Chen Qiaochu , Chen Qingwang , Chen Xingdong , Gao Yuechen , Jiang He , Li Bin , Li Bingying , Li Jingjing , Liu Ruimei , Qing Tao , Shang Erfei , Shang Jun , Sun Shanyue , Wang Haiyan , Wang Xiaolin , Zhang Naixin , Zhang Peipei , Zhang Ruolan , Zhu Sibo , Scherer Andreas , Wang Jiucun , Wang Jing , Huo Yinbo , Liu Gang , Cao Chengming , Shao Li , Xu Joshua , Hong Huixiao , Xiao Wenming , Liang Xiaozhen , Lu Daru , Jin Li , Tong Weida , Ding Chen , Li Jinming , Fang Xiang , Shi Leming 
Published: September 2023

Abstract
Characterization and integration of the genome, epigenome, transcriptome, proteome and metabolome of different datasets is difficult owing to a lack of ground truth. Here we develop and characterize suites of publicly available multi-omics reference materials of matched DNA, RNA, protein and metabolites derived from immortalized cell lines from a family quartet of parents and monozygotic twin daughters. These references provide built-in truth defined by relationships among the family members and the information flow from DNA to RNA to protein. We demonstrate how using a ratio-based profiling approach that scales the absolute feature values of a study sample relative to those of a concurrently measured common reference sample produces reproducible and comparable data suitable for integration across batches, labs, platforms and omics types. Our study identifies reference-free ‘absolute’ feature quantification as the root cause of irreproducibility in multi-omics measurement and data integration and establishes the advantages of ratio-based multi-omics profiling with common reference materials.
Spatial–temporal distribution of global production–living–ecological space during the period 2000–2020
Authors: Fu Jingying , Gao Qiang , Jiang Dong , Li Xiang , Lin Gang 
Published: September 2023

AbstractGlobal production-living-ecology space closely corresponds with sustainable development’s economic, social and ecological elements. The dataset of global production–living–ecological space in this paper was generated by combining the global land cover obtained using GlobeLand30 and the population density supplied by NASA’s Socioeconomic Data and Applications Center in 2000, 2010, and 2020. The verification was carried out using the random sampling function of ArcGIS software on the basis of Google Earth sample images. The overall accuracy of the global production–living–ecological space data in 2020 was 83.94% and the Kappa coefficient was 0.81. The overall accuracy of the global production–living–ecological space data in 2010 was 87.00% and the Kappa coefficient was 0.84. The overall accuracy of the spatial data in 2000 was 86.06% and the Kappa coefficient was 0.83. The dataset fills a gap in the global production-living-ecology space database and will be an essential reference for assessing the coordinated development of sustainable development goals.
RETRACTED ARTICLE: Synthesis and characterization of ZrFe2O4@SiO2@Ade-Pd as a novel, recyclable, green, and versatile catalyst for Buchwald–Hartwig and Suzuki–Miyaura cross-coupling reactions
Authors: Saadh Mohamed J. , Khasawneh Hussam Elddin Nabieh , Ortiz Geovanny Genaro Reivan , Ahsan Muhammad , Sain Dinesh Kumar , Yusuf Kareem , Sillanää Mika , Iqbal Amjad , Akhavan-Sigari Reza 
Published: September 2023

AbstractThis work presents the simple synthesis of a green and novel Palladium based magnetic nanocatalyst with effective catalytic properties and reusability. These heterogeneous catalysts were prepared by the anchoring of Pd(0) on the surface of ZrFe2O4 MNPs coated with a di-substituted adenine (Ade) compound as a green linker. The as-synthesized ZrFe2O4@SiO2@Ade-Pd MNPs were methodically characterized over different physicochemical measures like VSM, EDX, Map, SEM, TEM, ICP, and FT-IR analysis. The catalytic activity of ZrFe2O4@SiO2@Ade-Pd was carefully examined for the room-temperature Carbon–Carbon coupling reaction in acetonitrile as a solvent. It is worth noting that the synthesized solid catalyst can be easily recovered with a bar magnet and reused for five cycles without decrease of catalytic activity.