bluuebunny/crossref_metadata_2025_split huggingface dataset:
The foraminifera boogie
Authors: Holm Villads , Losleben Lisa Katrin , Zimmermann Heike Jane , Clerici Monica , Panieri Giuliana 
Published: April 2023

Focus:
To learn about foraminifera through practicing and presenting the song “The Foraminifera Boogie”. Pupils and teachers can also decide to play instruments along with the recorded soundtrack.
Learning objectives:
In this activity, pupils will practice listening to one another and the music. They will learn lyrics and use their voices to sing the song. This can be combined with playing actual musical instruments or using instruments the pupils have made themselves (for example see the activity “Cold Seeps Symphony”). This activity brings together music with the scientific story of the Foraminifera.
Key words:
Ocean, researchers, little known beings in the Arctic Ocean, co-living of humans and non-human beings, planetary time.
How deep is the ocean?
Authors: Maric Filip , Poto Margherita , Panieri Giuliana 
Published: April 2023

Focus:
To gain an appreciation of ocean depth using ideas of scale and physical education.
Learning objectives:
With these TWO activities, pupils will begin to understand (and feel) how deep the ocean can be in relation to their own size and height. They will get a feeling of the difference between height (above ground) and depth (in relation to water).
Key words:
Height, (ocean) depth.
Arctic Ocean temperatures
Authors: Maric Filip , Poto Margherita , Panieri Giuliana 
Published: April 2023

Focus:
To understand what water temperature is, and why it is important for life in the ocean. What factors influence water temperature (e.g., sunlight, solar radiation, heat transfer)?
Learning objectives:
In this activity, pupils will learn that temperature is an important factor influencing water, water quality, and altering the physical and chemical properties of water.
Key words:
Temperature, solar radiation, heat transfer, changes & drivers, consequences.
Sedimentation
Authors: Maric Filip , Poto Margherita , Panieri Giuliana 
Published: April 2023

Focus:
To understand the role of sedimentation in creating the unique conditions of ocean floor ecosystems.
Learning objectives:
With this activity, pupils will gain a basic understanding of how sediments in the ocean settle on the ocean floor (sedimentation) and what this looks like.
Key words:
Settling, sediment, terrigenous, pelagic.
Validation and cross-cultural adaptation of the Multiple Sclerosis Intimacy and Sexuality Questionnaire-15 (MSISQ-15) into Spanish
Authors: Esteve Ríos Antonio , Cabañero-Martínez María José , Escribano Silvia , Foley Frederick , García-Sanjuán Sofía 
Published: April 2023

Background
The Multiple Sclerosis Intimacy and Sexuality Questionnaire-15 (MSISQ-15) is a valid and reliable tool to assess the sexuality of people with multiple sclerosis. The objectives of this study were: 1) to cross-culturally adapt and examine the psychometric properties of the MSISQ-15 in the Spanish context and 2) to examine the association between sexual dysfunction and other related factors.

Methods
We conducted a instrumental study. People diagnosed with multiple sclerosis and members of multiple sclerosis associations in Spain were included. The linguistic adaptation of the questionnaire was performed through a translation-back translation procedure. For the psychometric validation, the confirmatory factor analysis was used while the internal consistency was examined by the ordinal alpha test. The construct validity was examined by correlating the results with the Male Sexual Function (FSH), Female Sexual Function-2 (FSM-2), Dyadic Adjustment Scale-13 (EAD-13) and Multiple Sclerosis International Quality of Life Questionnaire (MusiQoL) questionnaires.

Results
A total of 208 participants were included. Both the fit of the Spanish version of the MSISQ-15 to the original scale and the internal consistency were adequate (α = 0.89). The construct validity showed correlations with the FSH, FSM-2, and MusiQoL but not with the EAD-13.

Conclusions
The Spanish version of the MSISQ-15 is a valid and reliable tool to assess the sexuality of people with multiple sclerosis in the Spanish context.
An improved method for preparing stained ground teeth sections
Authors: Qin Qizhong , Li Yueheng , Zhou Yujian 
Published: April 2023

Objective
In oral histopathology teaching and research, there is a need for high-quality undemineralized tooth sections that are easy to handle, have controlled thickness, allow the observation of intact microstructures, and can be preserved for long periods of time.

Methods
Teeth were collected under non-demineralizing conditions. Tooth sections (15–25 µm) were prepared using a diamond knife, then randomly divided into three groups: (1) stained with rosin, (2) stained with hematoxylin and eosin, or (3) not stained. The prepared tooth sections were evaluated by microscopy for clarity and microstructure visibility.

Results
The use of a diamond knife in the sectioning and grinding process yielded high-quality ground sections of teeth. Rosin-stained ground sections allowed better identification of microstructures within the teeth, compared with unstained or hematoxylin and eosin-stained ground sections.

Conclusion
The best results were obtained in the ground sections of teeth that were stained with rosin. Ground sections of teeth prepared using this staining method could be useful in oral histopathology teaching and research.
The deployment of temporary nurses and its association with permanently-employed nurses’ outcomes in psychiatric hospitals: a secondary analysis
Authors: Oliveira Leonel , Gehri Beatrice , Simon Michael 
Published: April 2023

Aims
This study’s objective was to investigate possible associations between the frequency of temporary nurse deployments and permanently-employed nurses’ outcomes including staffing levels in Swiss psychiatric hospitals.

Background
Faced with widespread nursing shortages, some nursing managers frequently deploy temporary nurses to meet their staffing needs. While various studies have investigated the relationships between temporary nurses’ deployment and permanently-employed nurse outcomes, few anywhere, and none in Switzerland, have explored such deployments’ relationships with permanently-employed nurses’ job satisfaction, burnout, or intent to leave their organization or profession. Furthermore, especially in psychiatric hospitals, research on temporary nurse deployments and their association with permanently-employed nurses’ outcomes remains scarce.

Methods
This secondary analysis is based on the MatchRN Psychiatry study, which included 79 psychiatric units and 651 nurses. Using descriptive analyses and linear mixed modeling, we assessed the frequency of temporary nurses’ deployment and its association with four permanently-employed nurse outcomes: staffing levels, job satisfaction, burnout, and intention to leave their organization or profession.

Results
Roughly one-quarter of the studied units reported frequently deploying temporary nurses. Nonetheless, no differences in nurse staffing levels were found. Regarding permanently-employed nurses’ outcomes, we identified slightly higher levels of intention to leave the profession (beta = 0.18; 95% CI [0.03–0.33]) and burnout (beta = 0.19; 95% CI [0.4–0.33]) on units where temporary nurses were frequently deployed.

Conclusion
Deploying temporary nurses appears to help units maintain adequate staffing levels. However, additional research will be necessary to better understand whether working conditions are the common cause of temporary nurses’ deployment and permanently-employed nurse outcomes. Until more information is available, unit managers should consider alternatives to deploying temporary nurses.
Point Prevalence Survey of Antimicrobial Prescription and Indicators in a Tertiary Healthcare Center in Southern Nigeria
Authors: Awopeju A. T. O. , Robinson N. I. , Ossai-Chidi L. N. , Jonah A. A. , Alex-Wele M. A. , Oboro I. L. , Okoli C. D. , Duru C. C. , Ugwu R. , Yago-Ide L. E. , Paul N. I. , Wariso K. T. , Obunge O. K. 
Published: April 2023

Background: Antimicrobial stewardship programmes are interventions which have been developed to address irrational and inappropriate use particularly in health care centers. Antimicrobial stewardship programmes involve a set of activities which promote appropriate use of antimicrobials in terms of selection, dosing, route and duration of antimicrobial therapy.
Methods: A Point-prevalence survey (PPS) was organized in line with Global point prevalence patient-based protocol for PPS and antimicrobial use was carried out in the paediatrics department of a tertiary healthcare institution in southern Nigeria. A total of 66 inpatients on admission for at least 24hours and still on admission at 8am on the day of the survey were included in the study.
Results: The results show that 34 (51.50%) patients were on at least one antimicrobial drug and this included 19 (55.80%) males and 15 (44.20%) females. The highest proportion (n=15; 44%) of these patients were admitted in the children emergency ward while the least number (n=5; 14.7%) were found in children medical ward 1. The average age of patients on antimicrobials was 53 months. Thirty-four (51.50%) patients were on at least one antimicrobial drug and this included 19 (55.8%) males and 15 (44.2%) females. The three most prescribed antimicrobials were, ceftriaxone (23.88%), aminoglycoside gentamicin (20.90%), cefuroxime (16.42%) and Ceftazidime was the least common antibiotic prescribed (1.49%). Only 10.45 % were targeted therapy (based on microbiological results) while there was missing information for 10.45% of prescriptions.
Conclusion: The findings of the study shows that it is important to initiate antimicrobial stewardship programmes within our hospital to optimize antimicrobial use to improve patient care in the hospital.
Is psychotherapy any good?
Authors: Manning Seán 
Published: April 2023

This document is intended as a resource to stimulate discussion around the validity and effectiveness of psychodynamic psychotherapy and psychodynamic assessment. It is written in an atmosphere of, to this writer, unhelpfully argumentative debate between 'scientific' (symptom and behaviour oriented) clinical psychology, and the more descriptive, relationship-oriented psychotherapies, in which the latter have been criticised as unscientific and lacking evidence for their practice (Surgenor 2006).
Trends in Abortion- and Contraception-Related Internet Searches After the US Supreme Court Overturned Constitutional Abortion Rights
Authors: Gupta Sumedha , Perry Brea , Simon Kosali 
Published: April 2023

ImportanceThe US Supreme Court ruling in Dobbs v Jackson Women’s Health Organization on June 24, 2022, revealed immediate and distinct differences between states regarding abortion legality. Whether the ruling was associated with population-level changes in seeking information on reproductive health care-related information is unknown.ObjectiveTo determine whether the US Supreme Court ruling on Dobbs v Jackson Women’s Health Organization was associated with increased information seeking for reproductive health care access in the states with immediately effective (trigger and pre-Roe) abortion laws vs other states.Design, Setting, and ParticipantsThis was a retrospective cross-sectional study of nationwide real-time internet search data by state-week from January 1, 2021, through July 16, 2022. Difference-in-difference event study estimates were used to evaluate abortion- and contraception-related internet searches after the Supreme Court draft majority decision was leaked on May 2, 2022, and the final ruling was issued on June 24, 2022, in states immediately affected vs other states. Data analyses were performed from July 18 to January 14, 2022.ExposuresThe Supreme Court’s draft majority decision leaked on May 2, 2022, and the final ruling on Dobbs v Jackson Women’s Health Organization on June 24, 2022. Preexisting state trigger laws and pre-Roe bans that became effective immediately when Roe was overturned by the decision on Dobbs.Main Outcomes and MeasuresNumber of searches per 10 million Google queries in a state-week for terms related to abortion or contraception.ResultsSearches for abortion-related terms increased from 16 302 to 75 746 per 10 million searches per state-week during the weeks before vs after the May 2, 2022, leak of the draft majority decision in states with trigger laws or abortion bans. This was a 42% (95% CI, 24%-59%) higher increase than in states with laws that protect abortion access. Searches for contraception also increased from 56 055 to 82 133 searches per state-week after the ruling in the states with abortion bans, 25% (95% CI, 13%-36%) higher than the increase in states protecting abortion access.Conclusions and RelevanceThe findings of this retrospective cross-sectional study suggest that changes in internet searching for terms related to reproductive health care can capture immediate population-level changes in information-seeking behavior regarding reproductive health care access. These data are critical for shaping health policy discussions.
Treatment of US Children With Attention-Deficit/Hyperactivity Disorder in the Adolescent Brain Cognitive Development Study
Authors: Olfson Mark , Wall Melanie M. , Wang Shuai , Laje Gonzalo , Blanco Carlos 
Published: April 2023

ImportanceCharacterizing the extent and pattern of unmet needs for treatment of children with attention-deficit/hyperactivity disorder (ADHD) could help target efforts to improve access to ADHD medications and outpatient mental health care.ObjectiveTo describe current ADHD medication use and lifetime outpatient mental health care among a large national sample of children with ADHD.Design, Setting, and ParticipantsThis study uses cross-sectional survey data from the first wave of the Adolescent Brain and Cognitive Development Study (n = 11 723), conducted from June 1, 2016, to October 15, 2018, among 1206 school children aged 9 and 10 years who met parent-reported Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) criteria for current ADHD. Statistical analysis was performed from March 23, 2022, to March 10, 2023.Main Outcomes and MeasuresCurrent ADHD medications including stimulants and nonstimulants, lifetime outpatient mental health care, or either treatment. Weighted results are reported.ResultsAmong a sample of 11 723 children, 1206 had parent-reported ADHD (aged 9-10 years; 826 boys [68.2%]; 759 White, non-Hispanic children [62.2%]), 149 (12.9%) were currently receiving ADHD medications. Children receiving ADHD medications included a significantly higher percentage of boys (15.7% [121 of 826]) than girls (7.0% [28 of 108]), White children (14.8% [104 of 759]) than Black children (9.4% [22 of 206]), children of parents without a high school education (32.2% [9 of 36]) than of parents with a bachelor’s degree or higher (11.5% [84 of 715]), and children with the combined subtype of ADHD (17.0% [83 of 505]) than with the inattentive subtype (9.5% [49 of 523]). Approximately 26.2% of children (301 of 1206) with parent-reported ADHD had ever received outpatient mental health care. Children receiving outpatient mental health care included a significantly higher percentage of children whose parents had a high school education (36.2% [29 of 90]) or some college (31.0% [109 of 364]) than a bachelor’s degree or higher (21.3% [153 of 715]), children with family incomes of less than $25 000 (36.5% [66 of 176]) or $25 000 to $49 999 (27.7% [47 of 174]) than $75 000 or more (20.1% [125 of 599]), and children with the combined subtype of ADHD (33.6% [166 of 505]) than with the predominantly inattentive subtype (20.0% [101 of 523]) or the hyperactive-impulsive subtype (22.4% [34 of 178]) of ADHD.Conclusions and RelevanceThis cross-sectional study of children with parent-reported ADHD suggests that most were not receiving ADHD medications and had never received outpatient mental health care. Gaps in treatment, which were not directly associated with socioeconomic disadvantage, underscore the challenges of improving communication and access to outpatient mental health care for children with ADHD.
X‐Ray Visualized Sensors for Peritoneal Dialysis Catheter Infection
Authors: Kiridena Sachindra D. , Wijayaratna Uthpala N. , Levon Erin , Moschella Phillip , Pirrallo Ronald G. , Tzeng Tzuen‐Rong J. , Anker Jeffrey N. 
Published: April 2023

AbstractPeritonitis is a common complication for patients with end‐stage renal disease undergoing peritoneal dialysis (PD) and is a direct cause or contributor in >15% deaths in PD patients. Since early detection is key to treatment, patients and their care teams need rapid, on‐site diagnostics. A hydrogel‐based peritoneal fluid pH sensor attached to a peritoneal dialysis catheter is developed to measure local acidosis indicative of peritoneal infections for early detection and monitoring of infections using X‐ray imaging. The sensor comprises a polyacrylic acid hydrogel with embedded radiopaque markers enclosed in a polymer casing; contraction of the hydrogel in response to acidic pH is evident from the radiographically measured marker position. The sensor has a pH 4–8 response range; between pH 6.5 and 7.5 it responds linearly with a slope of 14% pH 7 length per pH unit, and about 1% length precision. The sensor is attached to a catheter and implanted in a rat peritoneum. Results in awake rats show a rapid pH drop during infection not observed in systemic C‐reactive proteins (CRP) levels nor in the uninfected control animal, with negligible drift over 2 weeks. To our knowledge, this is the first report of an in vivo chemically responsive hydrogel sensor.
ZnP‐Coated Zn1Cu0.1Ti Membrane with High Strength‐Ductility, Antibacterial Ability, Cytocompatibility, and Osteogenesis for Biodegradable Guided Bone Regeneration Applications
Authors: Tong Xian , Han Yue , Zhu Li , Zhou Runqi , Lin Zhiqiang , Wang Hongning , Huang Shengbin , Li Yuncang , Ma Jianfeng , Wen Cuie , Lin Jixing 
Published: April 2023

AbstractZinc (Zn) and its alloys have recently gained research interest due to their good biosafety, biological function, biodegradability, and formability. Zinc‐phosphate (ZnP) coating has been shown to improve the corrosion resistance and biocompatibility of Zn alloys. Here, a biodegradable ZnP‐coating on Zn1Cu0.1Ti (ZCT) membrane with high strength‐ductility and mechanical stability, suitable degradation rate, effective antibacterial ability, excellent in vitro and in vivo cytocompatibility, and osteogenesis is reported. The ZnP‐coated ZCT exhibits high strength‐ductility with a yield strength of 264 MPa, ultimate tensile strength of 312 MPa, elongation of 36.0%, and high mechanical stability before and after 30 d immersion in Hanks’ and AS solutions, all of which are higher than those of ZCT. The ZnP coating shows good deformation resistance, healing effect, and bond strength with the substrate, meeting the clinical contour shaping requirements. The ZnP‐coated ZCT membrane sample shows higher cell viability toward MC3T3‐E1 and MG‐63 cells, osteogenic and mitochondrial quality‐control properties in vitro than those of the ZCT sample. Using a rat calvarial defect model, the ZnP‐coated ZCT membrane shows complete biosafety and considerable osteogenesis performance. Overall, the ZnP‐coated ZCT membrane is recommended as a promising biodegradable implant material for oral guided bone regeneration application.
Biomimetic Periodontal Ligament Transplantation Activated by Gold Nanoparticles Protects Alveolar Bone
Authors: Zong Chen , Van Holm Wannes , Bronckaers Annelies , Zhao Zuodong , Čokić Stevan , Aktan Merve Kübra , Castro Ana Belén , Van Meerbeek Bart , Braem Annabel , Willems Guy , Cadenas de Llano‐Pérula Maria 
Published: April 2023

AbstractStem cell therapy might be a promising method to stimulate alveolar bone regeneration, which is currently a major clinical challenge. However, its therapeutic features largely depend on pretreatment and transplantation preparation. Herein, a novel biomimetic periodontal ligament transplantation composed of human periodontal ligament stem cells (hPDLSCs) pretreated with gold nanocomplexes (AuNCs) and embedded in a type‐I collagen hydrogel scaffold is developed to protect alveolar bone from resorption. AuNCs are readily absorbed by primary hPDLSCs, with limited cytotoxicity, and promote osteogenic differentiation of hPDLSCs effectively in vitro. In addition, the AuNCs‐induced hPDLSCs are encapsulated with type‐I collagen hydrogel scaffold to mimic their native physiological niche, and then are transplanted into a rat model of alveolar bone resorption. Both micro‐computed tomography (micro‐CT) and immunohistochemical assays demonstrate that alveolar bone loss is significantly prevented. Furthermore, the underlying therapeutic mechanism is elucidated, in which transplantation‐activated osteogenesis is associated with autophagy, which enables bone remodeling and regeneration. This study provides critical insight into the role of PDLSCs in bone homeostasis and proposes an innovative AuNCs‐based strategy for stem cell therapy in bone regeneration.
Microneedle‐Mediated Transcutaneous Immunization: Potential in Nucleic Acid Vaccination
Authors: Wang Haochen , Xu Junhua , Xiang Lin 
Published: April 2023

AbstractEfforts aimed at exploring economical and efficient vaccination have taken center stage to combat frequent epidemics worldwide. Various vaccines have been developed for infectious diseases, among which nucleic acid vaccines have attracted much attention from researchers due to their design flexibility and wide application. However, the lack of an efficient delivery system considerably limits the clinical translation of nucleic acid vaccines. As mass vaccinations via syringes are limited by low patient compliance and high costs, microneedles (MNs), which can achieve painless, cost‐effective, and efficient drug delivery, can provide an ideal vaccination strategy. The MNs can break through the stratum corneum barrier in the skin and deliver vaccines to the immune cell‐rich epidermis and dermis. In addition, the feasibility of MN‐mediated vaccination is demonstrated in both preclinical and clinical studies and has tremendous potential for the delivery of nucleic acid vaccines. In this work, the current status of research on MN vaccines is reviewed. Moreover, the improvements of MN‐mediated nucleic acid vaccination are summarized and the challenges of its clinical translation in the future are discussed.
Biomimetic Multicolor‐Separating Photonic Skin using Electrically Stretchable Chiral Photonic Elastomers
Authors: Nam Seungmin , Wang Dahee , Kwon Chaehyun , Han Sang Hyun , Choi Su Seok 
Published: April 2023

AbstractStructural color can be produced by nanoperiodic dielectric structures using soft materials. Chiral photonic elastomers (CPEs) produced from elastic chiral liquid crystal molecules can self‐organize into a helical nanostructure, and the chiral nanostructural color can be tuned by stretching. However, the ability to control the separation of biomimetic multicolors for practical applications beyond simple uniaxial stretching of single‐colored structures has been limited until now. Here, stretchable CPEs with simultaneous multicolor control, including electrical control, are presented. By engineering the heterogeneous elastic modulus of the CPEs, stretchable and simultaneous multicolor separations from an initially homogeneous color are realized. Electrically stretchable multicolor separation is investigated using a hybrid CPE structure on dielectric elastomer actuators, and multiarrayed color binning and chameleon‐like photonic e‐skin are further developed for device applications. Moreover, multicolor concealed camouflage switching and control of invisible photonic e‐skin are demonstrated. This multicolor control of stretchable photonic systems improves the functionality of various potential photonic applications.