bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of severe hand trauma injury frequency during “Munich’s Oktoberfest” within the last 9 years in comparison to years with absence due to the COVID-19 pandemic
Authors: Haas-Lützenberger Elisabeth M. , Kuhlmann Constanze , Giunta Riccardo E. , Kanz Karl-Georg , Steinbrunner Dieter , Rittberg Wendelin , Bogner-Flatz Viktoria , Hinzmann Dominik 
Published: January 2023

Abstract
Introduction
Within its 2 week period, the Oktoberfest attracts around 6 million visitors yearly to Munich, Germany. Due to alcohol intake, congested halls, and disorderly activities, numerous accidents occur. Although many hand injuries are observed, the impact of Oktoberfest on severe hand trauma injury frequency is under investigated.

Materials and methods
Data from the regional emergency medical service (EMS) was analyzed over a 9 year period regarding the frequency of severe hand injuries during the world’s largest fair and compared to the corresponding period in the years 2020 and 2021 where the event was cancelled due to the world-wide COVID-19 pandemic. Additionally, we compared the patient numbers during the same period in one Emergency Department of a level-1-trauma and hand trauma center located close to the venue.

Results
An exploratory description is made from data collected over a 9 year period (2013–2021) with focus on hand injuries before, during and after the “Oktoberfest”. A total of 4017 hand injuries were allocated to hospitals by EMS. There was an increase in severe hand injuries by 66% during the 2-weeks-Oktoberfest-period compared to years where the Oktoberfest did not take place. Pre-pandemic statistics show an increasing severe hand trauma frequency of 57.5% in September, compared to EMS-referrals during the remanding year.

Conclusion
The risk of injuring relevant structures of the hand during Oktoberfest is extremely high as compared to other parts of the body due to beer stein and fall-associated injuries. These injuries can lead to lifelong impairments. Our data are the first that quantifies and pinpoints the risk of severe injury to the hand during Oktoberfest and therefore, it is of great interest for visitors, hand surgeons, paramedics and emergency department healthcare workers.
Clinical evaluation of a new technique for custom-made spacers in septic two-stage revision of total hip arthroplasties
Authors: Mederake Moritz , Hofmann Ulf Krister , Fink Bernd 
Published: January 2023

Abstract
Introduction
In septic two-stage revision surgery, success depends on numerous factors. Key steps are the procedure of ex- and reimplantation and the choice of spacer in the interim phase. The latter is still a matter of debate. Recently, we showed the microbial non-inferiority of a spacer technique using prosthetic cemented implants with an individualized antibiotic mixture in the cement applying a mechanically inferior cementation method. The aim of the present study was to evaluate the clinical results of these spacers in view of either an endofemoral or a transfemoral procedure.

Materials and methods
Our collective consisted of 86 patients (45 endofemoral and 41 transfemoral procedures). The collective was analyzed with respect to complications, reinfection rate and clinical status at the end of the interim phase. Results of an endofemoral and transfemoral approach were compared.

Results
With a median Staffelstein-Score of 60 (range 31–81) at the end of the interim phase, the first clinical results are promising. The reinfection-free rate after a median follow-up of 50 months was 90%. Spacer-related complications occurred in 8% of the total collective. Comparing the endo- and transfemoral procedure, there were no statistical differences in complications or regarding the clinical and infectiological outcome.

Conclusions
In this study, we were able to show good clinical results for the presented spacer technique. With no relevant difference in outcome, the decision for an endofemoral or transfemoral technique can be based on technical deliberations. Further prospective comparative studies are necessary to show the clinical benefit of this procedure.
Impact of social exclusion on empathy in women with borderline personality disorder
Authors: Graumann Livia , Cho An Bin , Kulakova Eugenia , Deuter Christian Eric , Wolf Oliver T. , Roepke Stefan , Hellmann-Regen Julian , Otte Christian , Wingenfeld Katja 
Published: January 2023

AbstractUnstable interpersonal relationships and fear of abandonment are core symptoms of borderline personality disorder (BPD) that often intensify during stress. Psychosocial stress, which includes components of social exclusion and increases cortisol secretion, enhances emotional empathy in healthy individuals. Women with BPD, on the contrary, react with reduced emotional empathy. The aim of the present study was to investigate the effects of perceived social exclusion without accompanying cortisol increase on empathy in women with BPD and healthy women. To induce social exclusion, we randomized 98 women with BPD and 98 healthy women to either an exclusion or an overinclusion (control) condition of Cyberball, a virtual ball game. Subsequently, participants underwent the Multifaceted Empathy Test (MET), which assesses cognitive and emotional empathy. There was no increase in cortisol release after Cyberball. Cognitive empathy did not differ between groups or conditions. Women with BPD reported lower emotional empathy for positive emotions (group by valence interaction), but not for negative emotions. Exploratory analyses suggested that this effect might be more pronounced after social exclusion. Our results confirm previous findings that cognitive empathy does not differ between women with BPD and healthy women and extend this evidence to social exclusion. Emotional empathy in women with BPD seems to be more sensitive to the effects of stress or ambiguous social situations. Specifically, emotional empathy seems to be reduced for positive emotions, and might further decline after social exclusion. Empathic reactions to emotional stimuli of different valences and to specific emotions should be further investigated.
Self-esteem in stabilized individuals with chronic schizophrenia: association with residual symptoms and cognitive functioning
Authors: Hofer Alex , Biedermann Falko , Kaufmann Alexandra , Kemmler Georg , Pfaffenberger Nicole M. , Yalcin-Siedentopf Nursen 
Published: January 2023

AbstractLow self-esteem is regarded as a barrier to recovery from schizophrenia and the identification of factors affecting this psychological characteristic may help to implement effective therapeutic interventions. To this end, the present study aimed to assess whether residual symptoms of the disorder and performance on a comprehensive neuropsychological test battery might differently impact self-esteem among 70 stabilized outpatients with chronic schizophrenia from public outpatient mental health services. Self-esteem inter-correlated with the severity of overall symptomatology, affective and negative symptoms, with premorbid intelligence, and with performance in the domains of verbal learning and memory, visual memory, working memory, and verbal fluency. Residual affective symptoms, premorbid intelligence, and female sex predicted poorer self-esteem in multiple linear regression analysis. The findings of this study implicate that next to psychological interventions therapeutic strategies that specifically target affective symptoms of schizophrenia may have a beneficial impact on patients’ self-esteem.
First experiences with a diode laser in major gynecological laparoscopic procedures show lack of benefit and impaired feasibility
Authors: Spaich Saskia , Berlit Sebastian , Berger Laura , Weiss Christel , Tuschy Benjamin , Sütterlin Marc , Stefanovic Stefan 
Published: January 2023

Abstract
Purpose
The aim of this study is to evaluate feasibility and potential benefit of a diode laser in major laparoscopic procedures in gynecology.

Methods
Between 2018 and 2020, a total of 42 cases were enrolled in this study comparing standard electrosurgery with diode laser-supported therapy in laparoscopic supracervical hysterectomy (LASH), total laparoscopic hysterectomy (TLH), or laparoscopic myoma enucleation (LME). Dual wavelength 45 W diode laser light was used to cut and coagulate during laparoscopy in the prospective interventional arm consisting of 11 cases, while 31 matching patients who received conventional treatment with monopolar/bipolar current for the same interventions were retrospectively identified in our laparoscopy database. Recruitment in the prospective interventional laser diode arm was terminated after only 11 patients (instead of planned 50) due to intense hemorrhage and massive smoke development.

Results
A total of 42 cases were analyzed (11 LME, 19 LASH, and 12 TLH). Strong smoke development was evident in all 11 cases in the diode laser arm. It was necessary to convert to bipolar or monopolar current in all hysterectomies (n = 9) with initial diode laser implementation due to increased bleeding and smoke development. Conventional current sources had to be used in LMEs (n = 2) due to excessive bleeding and poor visibility during enucleation of the fibroid. A significant difference (p < 0.0001) was observed regarding smoke development when comparing the laser arm with the control arm.

Conclusion
We found a 45-W diode laser to be inferior to electrosurgical techniques for major laparoscopic gynecologic surgeries regarding bleeding control and smoke development.
Digital health—high tech or high touch?
Authors: Gangl Clemens , Krychtiuk Konstantin 
Published: January 2023

SummaryDigital transformation in medicine refers to the implementation of information technology-driven developments in the healthcare system and their impact on the way we teach, share, and practice medicine. We would like to provide an overview of current developments and opportunities but also of the risks of digital transformation in medicine. Therefore, we examine the possibilities wearables and digital biomarkers provide for early detection and monitoring of diseases and discuss the potential of artificial intelligence applications in medicine. Furthermore, we outline new opportunities offered by telemedicine applications and digital therapeutics, discuss the aspects of social media in healthcare, and provide an outlook on “Health 4.0.”
Explorative mathematical argumentation: a theoretical framework for identifying and analysing argumentation processes in early mathematics learning
Authors: Reuter Friederike 
Published: January 2023

AbstractThis paper introduces the termexplorative mathematical argumentation(EMA), signifying a concept for describing and analysing learners’ mathematical argumentation processes. Despite multiple recent empirical evidence for argumentation promoting learning in science education, still little is known about the development of early mathematical argumentation skills and their role within early learning processes. The widely varying use of the termargumentationimpedes respective research efforts. The concept of explorative mathematical argumentation offers an approach that takes into account the explorative nature of learners’ knowledge construction as well as specific aspects of mathematical argumentation. The concept of EMA promotes mathematical argumentation as a separate competence facet within which different forms and tools of reasoning can be deployed. It is suitable for describing and analysing learners’ mathematical argumentation processes from an early age onwards, as is illustrated by an exemplary situation with 4- and 5-year-old preschool children. Eventually, methods for identifying and analysing learners’ explorative mathematical argumentation processes are presented for discussion.
Error factors in precise thermal conductivity measurement using 3ω method for wire samples
Authors: Sekimoto Yuki , Abe Ryo , Kojima Hirotaka , Benten Hiroaki , Nakamura Masakazu 
Published: January 2023

AbstractIn designing thermoelectric and heat transfer devices on the micrometer scale, the accurate thermal conductivity measurement is very important, and a variety of measurement methods have been developed so far. Among them, the 3ω method is one of the best for conductive wires because it can directly measure thermal conductivity without measuring density or specific heat, and also in the same direction as electrical or thermoelectric property. However, previous studies have not sufficiently considered the effects of ambient pressure and the conductive adhesive used to attach the sample to the electrode, which may hinder accurate measurement. In this study, using a thin gold wire as a test sample, the influence of ambient pressure and the length of conductive adhesive along the sample has been investigated quantitatively as major factors of systematic errors in the 3ω method. When the pressure was increased in the transition flow region, the measured apparent thermal conductivity increased. An analytical model for the low-pressure gas heat conduction is proposed to quantitatively explain the pressure dependence. The measured value also increased when the length of the conductive adhesive exceeded 20% of the sample length. This work has revealed that the ambient should be evacuated to the molecular flow region and the length of conductive adhesive be less than 20% of the sample length. The guidelines proposed here will help researchers in various fields to more accurately determine the thermal conductivity of micrometer-scale wires.
Thermodynamic heat-transfer phenomena in nanostructured glassy substances: a comparative study on g-As5Se95 and g-As55Se45
Authors: Kozdras Andrzej , Shpotyuk Oleh , Mahlovanyi Bohdan , Shpotyuk Yaroslav , Kovalskiy Andriy 
Published: January 2023

AbstractNanostructurization-driven responses in calorimetric heat-transfer phenomena are compared for glassy arsenoselenides at different levels of their molecular network organization, namely in high-polymerized g-As5Se95 and low-polymerized g-As55Se45, employing multifrequency temperature-modulated DSC-TOPEM® method complemented with Raman scattering microspectroscopy. It is shown that high-polymerized network composed of AsSe3 pyramids interlinked by Se chains with small number of Se8 molecular units decoupled from this network prevails in melt-quenched and nanomilling-derived g-As5Se95. Transition to more polymerized network due to incorporation of destroyed Se8 molecules into glass backbone occurs in this glass under nanostructurization. As a result, nanostructurization-driven calorimetric response in g-As5Se95 dominates by size-induced glass-transition temperature depression. The low-polymerized structure of g-As55Se45 is built of As–Se network enriched with tetra-arsenic selenide molecular units decoupled from this network. Molecular-to-network transition owing to nanomilling-driven destruction of these cage molecules and their incorporation into newly polymerized glass-forming backbone occurs in g-As55Se45 resulting in strong increase in calorimetric glass-transition temperature.
Runge–Kutta–Möbius methods
Authors: Molnár András , Fekete Imre , Söderlind Gustaf 
Published: January 2023

AbstractIn the numerical integration of nonlinear autonomous initial value problems, the computational process depends on the step size scaled vector field hf as a distinct entity. This paper considers a parameterized transformation $$\begin{aligned} hf \mapsto hf \circ (I-\gamma hf)^{-1}, \end{aligned}$$

h
f
↦
h
f
∘

(
I
-
γ
h
f
)

-
1

,

and its role in the finite step size stability of singly diagonally implicit Runge—Kutta (SDIRK) methods. For a suitably chosen $$\gamma > 0$$

γ
>
0

, the transformed map is Lipschitz continuous with a reasonably small constant, whenever hf is negative monotone. With this transformation, an SDIRK method is equivalent to an explicit Runge–Kutta (ERK) method applied to the transformed vector field. Through this mapping, the SDIRK methods’ A-stability, and linear order conditions are investigated. The latter are closely related to approximations of the exponential function $$\textrm{e}^z$$

e
z

that are polynomial in z, when considering ERK methods, and polynomial in terms of the transformed variable $$z(1-\gamma z)^{-1}$$

z

(
1
-
γ
z
)

-
1

, in case of SDIRK methods. Considering the second family of methods, and expanding the exponential function in terms of this transformed variable, the coefficients can be expressed in terms of Laguerre polynomials. Lastly, a family of methods is constructed using the transformed vector field, and its order conditions, A-stability, and B-stability are investigated.
Surface heat flow measurements in the eastern margin of the Japan Sea using a 15 m long geothermal probe to overcome large bottom-water temperature fluctuations
Authors: Goto Shusaku , Yamano Makoto , Tanahashi Manabu , Matsubayashi Osamu , Kinoshita Masataka , Machiyama Hideaki , Morita Sumito , Kanamatsu Toshiya , Hachikubo Akihiro , Kataoka Satsuki , Matsumoto Ryo 
Published: January 2023

AbstractAccurate surface heat flow data are required for a wide range of geological and geophysical applications. However, sediment temperature measurements beneath the seafloor often involve large uncertainties owing to the influence of bottom-water temperature (BWT) fluctuations. Previous studies reported apparently negative geothermal gradients in the Joetsu Basin of the Japan Sea and suggested that BWT fluctuations disturbed sediment temperatures. To address this problem, we monitored BWTs in the Joetsu Basin over a 2 year period to determine the depth at which the influence of BWT fluctuations on sediment temperature becomes negligible. Combined with sediment thermal diffusivity data, we determined that the BWT fluctuations can disturb sediment temperatures to a depth of 2 m. We obtained heat flow values of 81–88 mW m− 2 by measuring sediment temperatures at depths > 2 m using a 15 m long geothermal probe. The measured heat flow values are inversely correlated with topography owing to the effect of topographic change on the geothermal structure near the seafloor. A two-dimensional geothermal structure model was constructed to account for the topography, yielding an estimated regional background heat flow of 85 ± 6 mW m− 2. This study provides two important guidelines for obtaining accurate surface heat flow data in marine areas with large-amplitude BWT fluctuations: (1) quantitative information regarding BWT fluctuations and sediment thermal diffusivity is required to evaluate the depth range to which BWT fluctuations affect sediment temperature; and (2) information regarding the lithology and consolidation state of seafloor sediments is required for effective penetration using a long probe.
Network intrusion detection system for DDoS attacks in ICS using deep autoencoders
Authors: Ortega-Fernandez Ines , Sestelo Marta , Burguillo Juan C. , Piñón-Blanco Camilo 
Published: January 2023

AbstractAnomaly detection in industrial control and cyber-physical systems has gained much attention over the past years due to the increasing modernisation and exposure of industrial environments. Current dangers to the connected industry include the theft of industrial intellectual property, denial of service, or the compromise of cloud components; all of which might result in a cyber-attack across the operational network. However, most scientific work employs device logs, which necessitate substantial understanding and preprocessing before they can be used in anomaly detection. In this paper, we propose a network intrusion detection system (NIDS) architecture based on a deep autoencoder trained on network flow data, which has the advantage of not requiring prior knowledge of the network topology or its underlying architecture. Experimental results show that the proposed model can detect anomalies, caused by distributed denial of service attacks, providing a high detection rate and low false alarms, outperforming the state-of-the-art and a baseline model in an unsupervised learning environment. Furthermore, the deep autoencoder model can detect abnormal behaviour in legitimate devices after an attack. We also demonstrate the suitability of the proposed NIDS in a real industrial plant from the alimentary sector, analysing the false positive rate and the viability of the data generation, filtering and preprocessing procedure for a near real time scenario. The suggested NIDS architecture is a low-cost solution that uses only fifteen network-based features, requires minimal processing, operates in unsupervised mode, and is straightforward to deploy in real-world scenarios.
The Effects of Long-term Molybdenum Exposure in Drinking Water on Molybdenum Metabolism and Production Performance of Beef Cattle Consuming a High Forage Diet
Authors: Thorndyke M. P. , Guimaraes O. , Medrado M. , Loh H. Y. , Tangredi B. V. , Reyes A. , Barrington R. K. , Schmidt K. , Tillquist N. M. , Li L. , Ippolito J. A. , Zervoudakis J. T. , Wagner J. J. , Engle T. E. 
Published: January 2023

AbstractFifty-four multiparous beef cows with calves were used to evaluate the effects of Mo source (feed or water) on reproduction, mineral status, and performance over two cow-calf production cycles (553 days). Cows were stratified by age, body weight, liver Cu, and Mo status and were then randomly assigned to one of six treatment groups. Treatments were (1) negative control (NC; basal diet with no supplemental Mo or Cu), (2) positive control (NC + Cu; 3 mg of supplemental Cu/kg DM), (3) NC + 500 µg Mo/L from Na2MoO4·2H2O supplied in drinking water, (4) NC + 1000 µg Mo/L of Na2MoO4·2H2O supplied in drinking water, (5) NC + Mo 1000-water + 3 mg of supplemental Cu/kg DM, and (6) NC + 3.0 mg of supplemental Mo/kg diet DM from Na2MoO4·2H2O. Animals were allowed ad libitum access to both harvested grass hay (DM basis: 6.6% crude protein; 0.15% S, 6.7 mg Cu/kg, 2.4 mg Mo/kg) and water throughout the experiment. Calves were weaned at approximately 6 months of age each year. Dietary Cu concentration below 10.0 mg Cu/kg DM total diet reduced liver and plasma Cu concentrations to values indicative of a marginal Cu deficiency in beef cows. However, no production parameters measured in this experiment were affected by treatment. Results suggest that Mo supplemented in water or feed at the concentrations used in this experiment had minimal impact on Cu status and overall performance.
Synthesis, Solid State Structure, and Cytotoxic Activity of a Complex Dimer of Yttrium with Anthranilic Acid against Cancer Cells
Authors: Zidan Amna S. A. , Ibrahim Ahmed B. M. , Aly Aref A. M. , Mosbah Hanan K. , Mayer Peter , Saber Saber H. 
Published: January 2023

AbstractThis paper presents the synthesis and isolation of a new binuclear complex of yttrium with anthranilic acid (HA). The complex [Y2(HA)6(H2O)4] Cl6.2C2H5OH (C1) was obtained as single crystals that its X-ray analysis revealed its triclinic P-1 space group in addition to anti-prismatic geometry around each of the yttrium ions. In the complex, the anthranilic acid ligands are bidentate, zwitter ionic and neutral, and the yttrium ions’ charge is only compensated by six chloride ions. The cytotoxicity of this complex against human breast cancer MDA-MB-231 cells, prostate cancer PC-3 cells, and bladder cancer T-24 cells was evaluated. This yttrium complex displayed more cytotoxic activity against the bladder cancer cells with an IC50 value of 307.7 μg/ml (223 μM). On the other hand, the activities of complex C1 against the MDA-MB-231 and PC-3 cells were less significant respectively with IC50 values of 1097 μg/ml (796 μM) and 921 μg/ml (669 μM).