bluuebunny/crossref_metadata_2025_split huggingface dataset:
High-Resolution Shear-Wave Velocity Structure of the 2019 Ms 6.0 Changning Earthquake Region and Its Implication for Induced Seismicity
Authors: Liu Qiaoxia , Zhou Ming , Tian Xiaofeng , Qiu Yong , Shen Zhichao , Wang Qingdong , Wang Chongpeng 
Published: March 2023

AbstractFluid injection activities related to hydraulic fracturing (HF) and salt mining may induce moderate earthquakes. In the Changning area in southwest China, the Ms 6.0 earthquake on 17 June 2019 is the largest and the most damaging event ever recorded in this region. This earthquake occurred in the Changning anticline, which hosts multiple active faults and industrial production activities, raising an extensive controversy on the cause of the earthquake. Beyond seismogenic faults, a detailed 3D velocity structure of the source region is missing. Here, we applied an improved ambient noise tomography method to seismic data recorded by a portable dense seismic array to reveal the characteristic of 3D shear-wave velocity (VS) structure with high resolution in the Changning region. Our VS structure model provides some new observational evidence favoring that the Ms 6.0 Changning earthquake and the related seismicity in Shangluo shale gas field were, respectively, induced by fluid injection for salt mining and hydraulic fracturing. Moreover, it is suggested that the shallow segment of the pre-existing thrust faults were reactivated by fluid injection. This result provides some implications of VS structure of the induced-seismicity source region and warn us to pay more attention to the seismic risk assessment for such areas that have both similar industrial operation intensity and tectonic settings.
Interchangeable Use of GNSS and Seismic Data for Rapid Earthquake Characterization: 2021 Chignik, Alaska, Earthquake
Authors: Parameswaran Revathy M. , Grapenthin Ronni , West Michael E. , Fozkos Alexander 
Published: March 2023

AbstractEarthquake magnitude estimation using peak ground velocities (PGVs) derived from Global Navigation Satellite Systems (GNSS) data has shown promise for rapid characterization of damaging earthquakes. Here, we examine the feasibility of using GNSS-derived velocity waveforms as interchangeable data for rapid magnitude and ground motion estimation that typically rely on strong-motion seismic records. Our study compares PGVs derived from high-rate GNSS to those computed from high-rate seismic records (strong-motion and velocity) at collocated and closely located stations. The recent 2021 Mw 8.2 Chignik earthquake in Alaska that was recorded on collocated GNSS and strong-motion sensors provides the perfect opportunity to compare the two data streams and their application in rapid response. The Chignik velocity records appear almost identical at collocated GNSS and strong-motion stations when observed at frequencies &lt;0.25 Hz. GNSS and strong-motion derived velocity data are further employed to generate rapid estimates of PGV-derived moment magnitudes for the earthquake. The moment magnitude estimates from GNSS and joint GNSS and joint (GNSS and seismic) data are within ∼±0.4 magnitude units (Fang et al., 2020) of the final magnitude (Mw 8.2). ShakeMaps generated for the 2021 Chignik earthquake using GNSS and seismic PGVs show notable agreement between them, and show negligible shifts in PGV contours when collocated and closely located GNSS and seismic stations are substituted for one another. Therefore, we posit that GNSS is a powerful alternative or addition to seismic data and vice versa.
Survey on Implementation of Early Literacy Interventions by Parents of Deaf Children
Authors: Sani Yulvia , Wardany Ossy Firstanti , Herlina Heni 
Published: March 2023

This study aims to determine whether parents of deaf children in Lampung conduct early literacy interventions. This research used a survey type quantitative method. The research subjects were 6 parents of deaf children aged 4-8 years. It collected data using a questionnaire distributed via Google Form to parents of deaf children. The study results found that 83 percent did early literacy intervention at home. Parents' activities to carry out early literacy intervention are reading aloud, natural intervention, using video, and making DIY media. All parents did the planning. The planning and implementation of early literacy intervention activities carried out by parents encountered various obstacles. Most of the solutions chosen were discussed with experts/therapists/ teachers. So it can be said that most parents of deaf children in Lampung Province carry out early literacy interventions planned and carried out through collaboration with families and expert assistance.
Comparative analysis of antioxidant activities of Vitex negundo and Ficus carica leaf extracts
Authors: Anjali  , Joshi Navneet 
Published: March 2023

Humans have been dependent on nature for various vital supplies and resources for a long time. Most biotechnological and pharmacological industries use chemicals and active compounds to treat diseases or make medications isolated from natural resources. A variety of plants have been explored for research of which Vitex negundo and Ficus carica are also examples as they are strong candidates for their potential antioxidant properties. In the current research, the anti-oxidant activities of V. negundo and F. carica leaf extracts were evaluated. The antioxidant activities of selected plants were analyzed using DPPH and FRAP assay. The results obtained from the DPPH assay indicated that methanolic extracts of V. negundo showed the highest inhibition of 90.07±1.17 percent at 1000 µl with IC50 value of 415.98 µg/ml followed by ethyl acetate and chloroform extracts (64.05±0.89 and 54.39±0.99 percent, respectively) with IC50 value of 751.96 µg/ml and 896.55 µg/ml when compared to F. carica extracts which showed highest inhibition of 75.75±1.08 percent at 1000 µl with IC50 value of 475 µg/ml followed by ethyl acetate and chloroform extracts (51.94±0.79 and 44.21±0.60 percent respectively) with IC50 value of 967.51 µg/ml and 1092.48 µg/ml. On comparing both plants, FRAP results indicated that methanol extracts of V. negundo showed the highest FRAP value (1042.1±0.98 µM) followed by ethyl acetate and chloroform extracts, which shows 996.6±1.25 µM and 949.6±1.63 µM at 1000 µl whereas F. carica showed highest FRAP value (995.6±1.35µM) followed by ethyl acetate and chloroform extracts, which shows 987.6±1.05µM and 447.6±1.01µM at 1000 µl. The results of the study can be concluded that among the tested extracts, the best antioxidant potential was exhibited with V. negundo leaf extracts, especially in methanol extracts.
Transformações do estado contemporâneo. O debate das políticas públicas e sociais (Paper 232)
Authors: Vidal Josep Pont 
Published: March 2023

Este escrito tem um duplo como objetivo. O primeiro é expor a evolução e analisar as mudanças e a reestruturação do Estado contemporâneo basicamente nas democracias ocidentais. O segundo, analisar como estas mudanças afetam a configuração das Políticas Sociais. O primeiro, pretende realizar este exercício de forma comparativa, limitando-se entre alguns países europeus e o Brasil a partir do nível analítico. Analisa-se o Estado de bem-estar, existindo importantes diferencia quanto a sua gênese, concepção, e reestruturação. O segundo objetivo, trata de analisar como as mudanças e reestruturação dos Estados afetam a concepção das Políticas Sociais, a partir do eixo de análise centrada na mercantilização e desmercantilização das políticas sociais. Com este trabalho se pretende contribuir a uma melhor compreensão da reforma e reestruturação do Estado de bem-estar e seus condicionantes atuais.Palavras-chave: Estado contemporâneo. Políticas públicas e sociais.
O Naea como Exu (um deus arquetípico): tributo a seus cofundadores, Armando Dias Mendes e José Marcelino Monteiro da Costa (Paper 311)
Authors: Maués Raymundo Heraldo 
Published: March 2023

O texto apresenta as origens do Núcleo de Altos Estudos Amazônicos da Universidade Federal do Pará, calcado nas histórias dos pesquisadores que formaram e construíram o Núcleo, juntamente com os processos de criação das pesquisas e estudos sobre o desenvolvimento regional na Amazônia. Informa as primeiras pesquisas realizadas e as monografias e dissertações oriundas os cursos de especialização e mestrado do NAEA.Palavras-Chave: Desenvolvimento Regional. Conhecimento Científico. Núcleo de Altos Estudos Amazônicos.
A Construção Social do Lazer e sua Trajetória Científica (Paper 309)
Authors: Chaar Bahia Mirleide , Lima Figueiredo Silvio 
Published: March 2023

Com as mudanças ocorridas na sociedade, o lazer nasce da dicotomia lazer x trabalho, gerando interesses e necessidades da classe trabalhadora em reivindicá-lo e das ciências sociais em estudá-lo. O objetivo principal desse artigo foi delinear a construção social do lazer e sua trajetória científica, considerando-se que o momento histórico de cada obra e suas representações sobre a realidade social da época trouxeram contribuições valiosas para a trajetória desse campo de estudos e para as reflexões sobre o atual modo de vida humano e possibilidade de transformações, emancipação e liberdade por meio do lazer. A metodologia utilizada tem cunho qualitativo e se alicerça em levantamento bibliográfico de teorias que tratam do lazer. Como resultado, percebe-se que as formas de vivências do lazer são diversificadas e se apresentam diferentemente, de acordo com os grupos que militam essas práticas, mais ou menos dependentes de padrões estruturadores. Além disso, a trajetória dos estudos do lazer no Brasil e no mundo não só revelam a centralidade que o tema vem ganhando em diversas áreas do conhecimento, mas também a criação de campos específicos interdisciplinares que tentam dar conta da diversidade de formas manifestas dessas práticas, e das políticas públicas atreladas a elas.Palavras-Chave: Lazer. Conceitos. Aspectos sociológicos. Teorias. Interdiciplinariedade.
Projeto assentamento agroextrativista e a construção do desenvolvimento sustentável das várzeas amazônicas (Paper 346)
Authors: Thomas Shaji , Almeida Oriana , Pinheiro Elysângela , Rivero Sérgio , Mori Jorge 
Published: March 2023

O objetivo dessa pesquisa é analisar os desafios trazidos pela criação do Projeto de Assentamento Agroextrativista no desenvolvimento sustentável das comunidades de várzea do Baixo Amazonas.Palavras-chave: Assentamento Agroextrativista. Desenvolvimento Sustentável. Várzeas da Amazônia.
Ajuste no índice de sustentabilidade dos municípios da Amazônia (ISMA) para Mato Grosso (Paper 358)
Authors: Bueno dos Santos Nagela , De Melo Faria Alexandre Magno 
Published: March 2023

A proposta deste paper é produzir uma visão mais realista do nível de desenvolvimento alcançado em Mato Grosso. Utilizou-se como base metodológica o Índice de Sustentabilidade dos Municípios da Amazônia (ISMA), com a proposta de inclusão de novos indicadores específicos e uma adaptação no método de cálculo (ISMA Ajustado). Verificou-se que a ação coordenadora do governo federal foi determinante para lançar as bases e consolidar o agronegócio como o atual modelo de desenvolvimento no estado. As políticas públicas, nesse sentido, foram orientadas de acordo com os objetivos definidos para os indicadores macroeconômicos do país em vez da adoção de políticas que priorizassem a ampliação generalizada das oportunidades dos indivíduos. De modo geral, o ISMA Ajustado apresentou um panorama pessimista do nível de desenvolvimento em Mato Grosso. Os fatores que mais contribuíram para esse cenário foram de cunho econômico e político-institucional. Tal resultado revelou-se um reflexo das instituições políticas e econômicas formadas na fase de constituição do atual modelo de desenvolvimento que ainda não puderam ser superadas. A aplicação do ISMA Ajustado demonstrou que adotar um índice mais complexo altera de maneira expressiva a classificação de desenvolvimento dos municípios em relação a outros indicadores amplamente utilizados. Palavras-chave: Sustentabilidade. Índice Municipal. Desenvolvimento em Mato Grosso.
An Immunostimulatory Glycolipid That Blocks
SARS-CoV-2, RSV, and Influenza Infections In Vivo
Authors: Ho David , Tsuji Moriya , Nair Manoj , Masuda Kazuya , Castagna Candace , Chong Zhenlu , Darling Tamarand , Seehra Kuljeet , Ribeiro Ágata , Ferreira Geovane , Corredor Laura , Coelho-dos-Reis Jordana Alves , Tsuji Yukiko , Boon Adrianus , Diamond Michael , Huang Yaoxing , Hwang Youngmin , Mori Munemasa 
Published: March 2023

Abstract
The fear and devastation caused by the COVID-19 pandemic has been mitigated by the successful development and deployment of prophylactic vaccines that substantially lowered the incidences of symptomatic infection, hospitalization, and death. However, as the causative agent SARS-CoV-2 continues to spread and evolve worldwide, vaccine-breakthrough infections have become frequent, especially after the emergence of viral variants that are antigenically distant from the ancestral strain used in the current vaccines. Additional approaches are therefore needed in our prevention tool kit. Here, we report on a glycolipid termed 7DW8-5 that exploits the host innate immune system to enable rapid control of viral infections in vivo. This glycolipid binds to CD1d on antigen-presenting cells and thereby stimulates NKT cells to release a cascade of cytokines and chemokines. The intranasal administration of 7DW8-5 prior to virus exposure significantly blocked infection by three different authentic variants of SARS-CoV-2, as well as by respiratory syncytial virus and influenza virus, in mice or hamsters. We also found that this protective antiviral effect is both host-directed and mechanism-specific, requiring both the CD1d molecule and interferon- gamma. A chemical compound like 7DW8-5 that is easy to administer and cheap to manufacture may be useful not only in slowing the spread of COVID-19 but also in responding to future pandemics that include currently ongoing influenza, SARS-CoV-2 and respiratory syncytia virus- associated tripledemic long before vaccines or drugs are developed.
Knowledge, Attitude and Worry in the Kurdistan Region of Iraq During the Mpox (Monkeypox) Outbreak in 2022: An Online Cross-sectional Study
Authors: Ahmed Sirwan Khalid , Abdulqadirb Salar Omar , Omar Rukhsar Muhammad , Abdullah Ardalan Jabbar , Rahman Hawre Asaad , Hussein Safin Hassan , M-Amin Halkawt Ismail , Chandran Deepak , Sharma Anil K. , Dhama Kuldeep , Salam Malik , Harapan Harapan , Salari Nader , Chakraborty Chiranjib , Abdulla Araz Qadir 
Published: March 2023

Abstract
The rapid spread of monkeypox (mpox) has been declared as a Public Health Emergency of International Concern (PHEIC). The present study aimed to assess the knowledge, attitude, and worry levels of the general population in the Kurdistan Region of Iraq regarding the ongoing mpox multi-country outbreak. An online cross-sectional survey was conducted between July 27 and July 30, 2022, using a convenience sampling method. The questionnaire was adapted from previous studies addressing the same topic. The independent Student t-test, one-way ANOVA, and logistic regression were used to assess possible factors associated with knowledge, attitude, and worry toward mpox. A total of 510 respondents were included in the final analysis. The participants showed moderate level of mpox knowledge, neutral attitude towards mpox, and a relatively moderate worry level. The logistic regression analysis showed that age, gender, marital status, religion, level of education, and place of residence were associated with mpox knowledge; however, the significant variables in the multivariate regression analysis were gender, religion, level of education, and residential area. Gender, and residential area were associated with attitudes toward mpox; however, the significant variables in the multivariate regression analysis were gender and residential areas. The worry toward mpox was influenced by gender, marital status, religion, and place of residence; however, the significant variables in the multivariate regression analysis were gender, religion, educational level and residential area. In conclusion, the Kurdish population had moderate knowledge, a neutral attitude, and a moderate level of worry about mpox. Considering the continuous rapid rise in mpox cases in several countries, and its possible risk as pandemic amid the ongoing COVID-19 pandemic, proactive control measures, adequate disease prevention strategies, and preparedness plans need to be formulated and immediately implemented to tackle the appearance of fears among people, and safeguard the mental health of the public.
Defining of the Supportive Care Needs of Using Hormone Therapy Patients Have Prostate Cancer and Caregivers
Authors: Tanış Esra Uslu , Uğur Özlem 
Published: March 2023

Abstract
Introduction This study aims to describe ways to alleviate the problems faced by prostate cancer patients undergoing using hormone therapy, as well as supporting their caregivers . It also describes the support care service needs of these two groups. Methods: This is a cross-sectional definitive study. The study involved 66 prostate cancer patients and 64 caregivers.
Results 79.9% of the caregivers were female and 43.8 % were patients’ wives. 36% of the patients had 80-90% performance rates on the Karnofsky scale.
9.32% of patients required support for sexual issues before and after the diagnosis, and 46.27% needed supportive care for water retention. Of the caregivers, 40.88% needed family support, and 21.25% needed social services support. It was found that prostate cancer patients receiving hormone therapy and their caregivers had a range of supportive care needs due to the difficulties they faced.
Noninvasive electrophysiological imaging identifies 4D uterine peristalsis patterns in subjects with normal menstrual cycles and patients with endometriosis
Authors: Wang Sicheng , Anderson Kelsey , Pizzella Stephanie , Xu Haonan , Wen Zichao , Lin Yiqi , Nan Yuan , Lau Josephine , Wang Qing , Ratts Valerie , Wang Yong 
Published: March 2023

Abstract
Throughout the menstrual cycle, spontaneous mild contractions in the inner layer of the uterine smooth muscle cause uterine peristalsis, which plays a critical role in normal menstruation and fertility. Disruptions in peristalsis patterns may occur in women experiencing subfertility, abnormal uterine bleeding, ovulatory dysfunction, endometriosis, and other disorders. However, current tools to measure uterine peristalsis in humans have limitations that hamper their research or clinical utilities. Here, we describe an electrophysiological imaging system to noninvasively quantify the four-dimensional (4D) electrical activation pattern during human uterine peristalsis with high spatial and temporal resolution and coverage. We longitudinally imaged 4968 uterine peristalses in 17 participants with normal gynecologic anatomy and physiology over 34 hours and 679 peristalses in 5 participants with endometriosis over 12.5 hours throughout the menstrual cycle. Our data provide quantitative evidence that uterine peristalsis changes in frequency, direction, duration, magnitude, and power throughout the menstrual cycle and is disrupted in endometriosis patients. Moreover, our data suggest that disrupted uterine peristalsis contributes to excess retrograde menstruation and infertility in patients with endometriosis and potentially contributes to infertility in this cohort.
Effectiveness of low-intensity pulsed ultrasound for the treatment of viral pneumonia: study protocol for a prospective, randomized controlled trial
Authors: Li Xiao , Li Wen , Sun Lianjie , Ren Junyi , Xu Ying , Zheng Yuanyi , Bai Wenkun 
Published: March 2023

Abstract
Background: Viral pneumonia has always been a problem faced by clinicians because of its insidious onset, strong infectivity and lack of effective drugs. Patients with advanced age or underlying diseases may experience more severe symptoms and are prone to severe ventilation dysfunction. Reducing pulmonary inflammation and improving clinical symptoms is the focus of current treatment. Low-intensity pulsed ultrasound (LIPUS) can mitigate inflammation and inhibit edema formation. We aimed to investigate the effectiveness of therapeutic LIPUS in improving lung inflammation in hospitalized patients with viral pneumonia.
Methods: This study protocol entails a prospective, randomized controlled trial. 60 eligible participants with clinically confirmed viral pneumoniawill be assigned to either (1) test group (LIPUS stimulus), (2) external control group (null stimulus), or (3) self-control group (LIPUS stimulated areas versus non-stimulated areas). The primary outcome will be the difference in the extent of absorption and dissipation of lung inflammation on computed tomography andultrasonography images. Secondary outcomes include pulmonary function, blood gas analysis, fingertip arterial oxygen saturation, serum inflammatory factor levels, the sputum excretion volume, time to the disappearance of pulmonary rales, pneumonia status score, and course of pneumonia. Adverse events will be recorded. Intention-to-treat analyses will be used.
Discussion: This study is the first clinical study of the effectiveness of therapeutic LIPUS in the treatment of viral pneumonia. Given that the current clinical recovery mainly depends on the body's self-limiting and conventional symptomatic treatment, LIPUS, as a new therapy method, might be a major advance in the treatment of viral pneumonia.
Trial registration: ChiCTR2200059550 Chinese Clinical Trial Registry