bluuebunny/crossref_metadata_2025_split huggingface dataset:
Auf Betalaktamantibiotika bei anamnestischer „Penicillinallergie“ verzichten?
Authors: Massoth Christina , Saadat-Gilani Khaschayar , Wenk Manuel 
Published: April 2023

AbstractDrug allergies are frequently reported by patients undergoing pre-anesthesia evaluation, potentially resulting in a suboptimal treatment with alternative substances. While about 10% of
patients report to be allergic to penicillin, less than 1% have a true IgE-mediated allergy. Multiple factors contribute to this large prevalence, such as misinterpretations of common
gastrointestinal side effects as “allergic”, a history of penicillin treatment for infectious mononucleosis resulting in skin rashes, uncritical acceptance of the diagnosis by medical staff
or neglect to the fact that most patients will lose their sensitivity after 10 years. In addition to this, cephalosporins are regularly withheld from patients with penicillin allergy due to
an unwarranted fear of cross-reactivity. Therefore, a correct identification of those in which penicillins or cephalosporins are truly contraindicated is paramount to avoid an unnecessary
use of antibiotics with a less favorable spectrum.
Umsetzung der Reform der Psychotherapie-Richtlinie 2017: Ergebnisse
aus Fokusgruppen im Rahmen des Innovationsfonds-Projekts EVA
PT-RL
Authors: Abels Carina , Diekmann Sandra , Neusser Silke , Schlierenkamp Sarah , Wasem Jürgen , Walendzik Anke 
Published: April 2023

Zusammenfassung
Hintergrund Psychische Erkrankungen verursachen sowohl individuelle als
auch gesellschaftliche Belastungen. Zentrales Ziel der Strukturreform der
Psychotherapie-Richtlinie (Inkrafttreten 2017) war die verbesserte Steuerung des
Zugangs zur psychotherapeutischen Versorgung. Die hier vorgestellten
Fokusgruppen, die im Rahmen des durch den Innovationsfonds geförderten
Forschungsprojekts „Evaluation der Psychotherapie-Richtlinie (Eva
PT-RL)“ durchgeführt wurden, adressieren die Umsetzung der Ziele
der Reform und der einzelnen neu eingeführten Versorgungselemente sowie
Hürden bei der Implementierung aus der Perspektive von
Leistungserbringer*innen, Patient*innen und
Kostenträgern.
Methoden Es wurden sechs Fokusgruppen und fünf Einzelinterviews
mit Personen der drei genannten Stakeholder-Gruppen durchgeführt.
Grundlage war ein an die jeweilige Personengruppe angepasster auf Basis einer
strukturierten Literaturrecherche erstellter halbstrukturierter
Gesprächsleitfaden. Die Gespräche wurden von einem
Moderatorinnenteam per Videokonferenz durchgeführt, aufgezeichnet und
transkribiert. Die Auswertung erfolgte über eine qualitative
Inhaltsanalyse in Anlehnung an Mayring.
Ergebnisse Eine allgemein positive Beurteilung insbesondere hinsichtlich
des Erstzugangs zur psychotherapeutischen Versorgung erfuhr die
psychotherapeutische Sprechstunde, wobei gleichzeitig ein verzögerter
Übergang zur gegebenenfalls folgenden Richtlinien-Psychotherapie
insbesondere aufgrund Kapazitätenmangels kritisch diskutiert wurde. Es
wurden günstige Effekte der telefonischen Erreichbarkeitszeiten sowie
einer verstärkten Vernetzung der psychotherapeutischen Versorgung auch
mit anderen psychosozialen Angeboten angesprochen. Die Umsetzung der
Akutbehandlung und der Rezidivprophylaxe wurde jedoch eher kritisch diskutiert.
Als zentrales Ergebnis zeigt sich, dass der durch die Reform angestrebte
Anstoß zum Paradigmenwechsel von Psychotherapeut*innen
unterschiedlich wahrgenommen und umgesetzt wird – von einem Fokus auf
individuelle Therapieprozesse hin zur Public Mental Health-Perspektive mit einer
Verpflichtung zur Versorgungssteuerung.
Schlussfolgerung Angesichts der variablen Strategien zur Umsetzung der
Strukturreform durch die Psychotherapeut*innen, der Kritik an der
Ausgestaltung einzelner Reformelemente und der Diskussion um
Verzögerungen beim Zugang zur Richtlinientherapie aus der
psychotherapeutischen Sprechstunde besteht weiterer Forschungsbedarf. Die
Ergebnisse der Fokusgruppen dienen als Grundlage für die folgenden
Projektschritte, u. a. eine Befragung von Psychotherapeut*innen,
Patient*innen und hausärztlich tätigen
Ärzt*innen.
Immune Thrombocytopenic Purpura Presenting with Pituitary Apoplexy: A Case Report and Literature Review
Authors: Nabulsi Omar , Abouelleil Mohamed , Lyons Leah , Walsh Meggen , Singer Justin 
Published: April 2023

Abstract
Background Pituitary apoplexy is a rare condition that usually occurs in the setting of a pituitary adenoma. It can present with symptoms of visual disturbances, vertigo, headache, and neurological impairments. Computed tomography (CT) scans can aid in identifying pituitary apoplexy and ruling out other diseases. We present a unique case of pituitary apoplexy in the setting of immune thrombocytopenic purpura (ITP).
Case Description A 61-year-old man with a past medical history significant for myocardial infarction presented to the emergency department with symptoms of diplopia and headache 36 hours after onset. The patient was found to have severe thrombocytopenia with a platelet count below 20,000. A CT of the head revealed a possible pituitary adenoma with compression of the optic chiasm. The patient's platelet count continued to decrease throughout his admission and dropped below 7,000 on day 2 of admission. The patient was given platelet transfusion along with intravenous immunoglobulins. The patient underwent endoscopic transsphenoidal resection of the pituitary mass. Pathology of the mass revealed immature platelets characteristic of immune ITP in the setting of pituitary apoplexy.
Conclusion While ITP in the setting of pituitary apoplexy is a rare entity, we believe that clinicians should have pituitary apoplexy on their differential diagnosis in patients with ITP.
Regiodivergent Synthesis of Oxadiazocines via Dirhodium-Catalyzed Reactivity of Oxazolidines and α-Imino Carbenes
Authors: Lacour Jérôme , Viudes Olivier , Guarnieri-Ibáñez Alejandro , Besnard Céline 
Published: April 2023

AbstractUsing electron-rich or electron-poor N-substituted oxazolidines as substrates, selective formation of either ammonium or oxonium ylides is possible in the presence of α-imino carbenes. As such, treatment of 5-membered oxazolidine precursors with N-sulfonyl-1,2,3-triazoles under dirhodium catalysis (2 mol%) affords the regiodivergent synthesis of either 8-membered 1,3,6- or 1,4,6-oxadiazocines upon the initial N or O reactivity with the carbene.
Antibiotic Protocols for Endophthalmitis Prophylaxis Following Open-Globe Repair: A Survey of U.S. Residency Programs
Authors: Fell David , Blomquist Preston H. 
Published: April 2023

Abstract
Purpose To assess the various approaches to endophthalmitis prevention following traumatic open-globe injury (OGI) repair.
Methods A research electronic data capture (REDCap) questionnaire evaluating the usage of antibiotics and steroids in patients with OGI was distributed to program directors of all U.S. ophthalmology residency programs using the Association of University Professors of Ophthalmology program directors' listserv. Completed questionnaires were analyzed for treatment patterns.
Results The REDCap questionnaire was distributed to 111 programs, with 32 residency programs responding. Two responses were excluded. Ninety percent (27/30) of included programs used perioperative intravenous (IV) antibiotics, with 78% (21/27) of those giving one dose only. At the time of surgery, 27% (8/30) of programs gave intravitreal antibiotics and 60% (18/30) gave subconjunctival antibiotics. Postoperatively, 100% (30/30) gave topical antibiotics and 97% (29/30) gave topical steroids. Only 53% of responders discharged patients on oral antibiotics. Of the three programs who did not use IV antibiotics, all three gave intravitreal therapy and one also discharged patients on oral antibiotics.
Conclusion There is a large variation in practice patterns for endophthalmitis prophylaxis among residency programs. Further investigation is needed to compare rates of endophthalmitis between these protocols and establish a safe and minimally burdensome standard of care.
Accuracy and Utility of Internet Image Search as a Learning Tool for Retinal Pathology
Authors: Cobbs Lucy V. , Al-Hindi Hytham , Fathy Cherie , Mahmoudzadeh Raziyeh , Uhler Tara , Xu David 
Published: April 2023

Abstract
Purpose Ophthalmology residency training heavily relies on visual and pattern recognition-based learning. In parallel with traditional reference texts, online internet search via Google Image Search (GIS) is commonly used and offers an accessible fund of reference images for ophthalmology trainees seeking rapid exposure to images of retinal pathology. However, the accuracy and quality of this tool within this context is unknown. We aim to evaluate the accuracy and quality of GIS images of selected retinal pathologies.
Methods A cross-sectional study was performed of GIS of 15 common and 15 rare retinal diseases drawn from the American Academy of Ophthalmology residency textbook series. A total of 300 evaluable image results were assessed for accuracy of images and image source accountability in consultation with a vitreoretinal surgeon.
Results A total of 377 images were reviewed with 77 excluded prior to final analysis. A total of 288 (96%) search results accurately portrayed the retinal disease being searched, whereas 12 (4%) were of an erroneous diagnosis. More images of common retinal diseases were from patient education Web sites than were images of rare diseases (p < 0.01). Significantly more images of rare retinal diseases were found in peer-reviewed sources (p = 0.01).
Conclusions GIS search results yielded a modest level of accuracy for the purposes of ophthalmic education. Despite the ease and rapidity of accessing multimodal retinal imaging examples, this tool may best be suited as a supplementary resource for learning among residents due to limited accuracy, lack of sufficient supporting information, and the source Web site's focus on patient education.
Integrating socio-cultural value system into health services in response to Covid-19 patients’ self-isolation in Indonesia
Authors: Rochwulaningsih Yety , Sulistiyono Singgih Tri , Utama Mahendra Puji , Masruroh Noor Naelil , Sholihah Fanada , Yudha Fajar Gemilang Purna 
Published: April 2023

AbstractThis article studies the synergistic sociocultural value system to handle COVID-19 patients in self-isolation in Indonesia, to find an effective formula in COVID-19 spread control. The problems studied here is the response carried out and the constraints faced by the Indonesian government related to the self-isolation policy. Why and how does the Indonesians’ sociocultural value system contribute to COVID-19 patient response? Through the survey conducted via Google Forms, in-depth interviews, focus group discussions and literature study, it is found that the Indonesian government issued the self-isolation regulation for COVID-19 patients to mitigate the rapid and massive COVID-19 transmission. However, many constraints are found in the policy implementation, including; people’s insufficient knowledge and understanding of COVID-19, leading to negative implications for the COVID-19 survivors or patients’ perception, causing social stigmatisation for COVID-19 survivors or patients; COVID-19 task force’s limited access to medicine, medical instrument and hospital facilities. Meanwhile, the Indonesians’ strong socio-cultural values like tolerance, mutual aid, and communal work, including among the educated people in urban society, may be potentially integrated into the health service to respond to COVID-19 patients with their self-isolation. Therefore, their integration and empowerment can be a solution to mitigating COVID-19 transmission in Indonesia.
Earnings management and financial distress or soundness determining CEOs’ future over- and under-investment decisions
Authors: Sumiyana Sumiyana , Na’im Ainun , Kurniawan Firdaus , Nugroho Albertus H. L. 
Published: April 2023

AbstractThis study investigates the association between CEOs’ over-confidence in experiencing financial distress or soundness, future earnings management, and over and under-investment decisions. Specifically, it makes deeper the association between financial distress (soundness), requiring to increase (decrease) earnings management and over (under)-investment decisions. Methodologically, the authors demonstrate the CEOs’ aggressive behaviour in managing their firms’ earnings in developing countries. In other words, it shows a literature gap in some extant research that most CEOs in developing countries would intentionally manage future earnings for constructing future investment decisions. Then, it highlights that CEOs in developing countries tend to be over-confident because of cognitive distortion, assembling the earnings management to improve future performance. Finally, this study presents a newness with three critical reasoning arguments. First, this study uses the prospect theory, framing, conservatism and psychological projection to explain the CEOs’ future investment decisions due to past earnings information, which causes their behaviour to be more optimistic. Second, this research considers that financial distress or soundness influences the association between earnings management and future over(under) investment decisions. Third, this study investigates CEOs’ over-confidence using an international setting due to characteristic differentiation between advanced and developing countries, influencing this association.
Study of lithium incorporation in (111) NiO epitaxial layers grown on c-sapphire substrates using the pulsed laser deposition technique
Authors: Sahu Bhabani Prasad , Yadav Santosh Kumar , Arora Simran , Dhar Subhabrata 
Published: April 2023

Abstract
Incorporation of lithium in (111) NiO epitaxial layers grown using the pulsed layer deposition technique on c-sapphire substrates is studied as functions of growth conditions. The effect of Li-inclusion on the structural, morphological, electrical and optical properties of the films have been systematically investigated. It has been found that the concentration of Li in the film is more at lower growth temperatures. However, the crystalline quality deteriorates as the growth temperature is lowered. The investigation suggests that there is a miscibility limit of Li in nickel oxide (NiO). Beyond a critical concentration of lithium, Li-clusters are detected in the films. Further, it has been found that inclusion of Li gives rise to hydrostatic tensile strain in the NiO lattice that results in the reduction of the bandgap. The study also suggests that Li incorporation improves the electrical conductivity of NiO layers. Ni-vacancy defects also play an important role in governing the conductivity of these samples.
Entropies for factor maps of amenable group actions
Authors: Zhang Guohua , Zhu Lili 
Published: April 2023

Abstract
In this paper we study various entropies for factor maps of amenable group actions. We prove firstly theorem 3.1 inequalities linking relative topological entropy and conditional topological entropy (for factor maps of amenable group actions) without any additional assumption, which strengthens conditional variational principles (Zhu 2021 Nonlinearity
34 5163–85, theorems 2.12 and 3.9) proved by Zhu under additional assumptions. Then along the line of Misiurewicz (1976 Studia Math.
55 175–200), we introduce a new invariant called relative topological tail entropy and prove a Ledrappier’s type variational principle concerning it (for factor maps of amenable group actions); consequently, any factor map with zero relative topological tail entropy admits invariant measures with maximal relative entropy, which provides a nontrivial sufficient condition for the existence of invariant measures with maximal relative entropy in the setting of factor maps of amenable group actions.
A Number Estimate of Detectable Detached Black Hole-star Binaries using a Photometric Telescope
Authors: Hu Zhe-Cheng , Yang Yan-Lv , Wen Yuan-Hao , Shen Rong-Feng , Thomas Tam Pak-Hin 
Published: April 2023

Abstract
Detached and wide-orbit black hole-star binaries (BHSBs) can generate three types of periodic photometric signals: Ellipsoidal Variation, Doppler beaming and Self-Lensing (SL), providing a proxy to discover these black holes. We estimate the relative amplitude of the three signals for such systems and the detectability for black holes of a photometric telescope like Kepler in several steps. We estimate the searchable star number by assuming every star has a black hole companion, and apply the occurrence of BHSBs in field stars to estimate the detectable black hole signals. We consider three types of Initial Mass Function (IMF) model with different high end exponential slopes. “When spot and white noise are both considered, there is about one detectable signal for SL and less than one event is expected for beaming and Ellipsoidal Variation signal in Kepler Input Catalog stars with the standard IMF model.â to âDue to contamination by stellar spots and white noise, one may expect one detectable signal for SL and less than one detectable signal for both beaming and Ellipsoidal Variation in Kepler Input Catalog stars with the standard IMF model.” On the other hand, if we assume that only white noise affects the detection efficiency of the BHSBs, we expect about 10 Ellipsoidal Variation signals and 17 beaming signals to be detectable while the number of SL signals remains unchanged.
The FAST Galactic Plane Pulsar Snapshot Survey. II. Discovery of 76 Galactic Rotating Radio Transients and the Enigma of RRATs
Authors: Zhou D. J. , Han J. L. , Xu Jun , Wang Chen , Wang P. F. , Wang Tao , Jing Wei-Cong , Chen Xue , Yan Yi , Su Wei-Qi. , Gan Heng-Qian , Jiang Peng , Sun Jing-Hai , Wang Hong-Guang , Wang Na , Wang Shuang-Qiang , Xu Ren-Xin , You Xiao-Peng 
Published: April 2023

Abstract
We have carried out the Galactic Plane Pulsar Snapshot (GPPS) survey by using the Five-hundred-meter Aperture Spherical radio Telescope (FAST), the most sensitive systematic pulsar survey in the Galactic plane. In addition to more than 500 pulsars already discovered through normal periodical search, we report here the discovery of 76 new transient radio sources with sporadic strong pulses, detected by using the newly developed module for a sensitive single-pulse search. Their small DM values suggest that they all are Galactic rotating radio transients (RRATs). They show different properties in the follow-up observations. More radio pulses have been detected from 26 transient radio sources but no periods can be found due to a limited small number of pulses from all FAST observations. The follow-up observations show that 16 transient sources are newly identified as being the prototypes of RRATs with a period already determined from more detected sporadic pulses, and 10 sources are extremely nulling pulsars, and 24 sources are weak pulsars with sparse strong pulses. On the other hand, 48 previously known RRATs have been detected by the FAST, either during verification observations for the GPPS survey or through targeted observations of applied normal FAST projects. Except for one RRAT with four pulses detected in a session of 5-minute observation and four RRATs with only one pulse detected in a session, sensitive FAST observations reveal that 43 RRATs are just generally weak pulsars with sporadic strong pulses or simply very nulling pulsars, so that the previously known RRATs always have an extreme emission state together with a normal hardly detectable weak emission state. This is echoed by the two normal pulsars J1938+2213 and J1946+1449 with occasional brightening pulses. Though strong pulses of RRATs are very outstanding in the energy distribution, their polarization angle variations follow the polarization angle curve of the averaged normal pulse profile, suggesting that the predominant sparse pulses of RRATs are emitted in the same region with the same geometry as normal weak pulsars.
Steady-state and fluorescence lifetime quenching of self-assembled diphenylalanine/coumarin nanostructures as a method to determine dissolved O2in water
Authors: Souza Geovany A , Cordeiro Diéricon S , Ernter Tatiana D M 
Published: April 2023

AbstractA fluorescent system formed by the combination of coumarin derivative and self-assembled peptide nanostructures was used as sensing system to determine dissolved oxygen (O2) in water samples. Detection was based on the sensing system fluorescence quenching by O2, measured by steady-state and time-resolved fluorescence spectroscopy and Stern-Volmer plot to correlate fluorescence intensity to O2concentration in the samples. Also, fluorescence lifetime decays informed about the mechanisms in which the quenching is occurring, indicating that the sensing system is highly sensitive and selective to O2, since quenching occurs by a non-radiative energy transfer from electronic excited singlet states of the system to the O2molecule. This process was evidenced by the system fluorescence lifetime decrease, yielding Singlet O2as indicative that this system can also find other technological applications.
On the potential application of surface plasmon-based core-shell particles to study blood functional parameters
Authors: Sathiyamoorthy K , Kolios Michael C 
Published: April 2023

Abstract
We investigated the application of gold nanoshell particles as optical sensors and contrast agents to study the blood functional parameters. Gold nanoshell particles with a core size of 1 μm that exhibit two prominent plasmonic peaks at 750 and 830 nm were developed. The peaks correspond to the wavelengths typically used to study the oxygen saturation of the blood. The plasmonic properties of gold nanoshells in media with various refractive indices were studied. Glucose samples with concentrations 0, 15, and 20%w/v in water were used. The 750 and 830 nm plasmonic peaks exhibit peak wavelength shifts of 63.77 ± 49.40 nm and 31.18 ± 20.94 nm per unit refractive index change. The optical properties of blood samples mixed with gold nanoshells were also measured. The optical absorption of blood samples increased by 7% at these wavelengths in the presence of the nanoshells. The plasmonic peaks at 750 and 830 nm showed a 3.57 ± 0.56 and 1.44 ± 0.55 percentage variation in absorbance for a 1% change in hematocrit. The enhanced optical absorption at these wavelengths suggests that these particles are effective optical sensors/contrast agents for multimodal optical and photoacoustic sensing and imaging.
Carbon dioxide removal to combat climate change? An expert survey on perception and support
Authors: Kerner Christoph , Thaller Annina , Brudermann Thomas 
Published: April 2023

Abstract
The most recent IPCC report considers Carbon Dioxide Removal (CDR) as an unavoidable climate change mitigation measure, although controversial discussions about CDR have taken place in the past. This study contributes to the ongoing debate by providing insights into academic expert opinions about Bioenergy with Carbon Capture and Storage (BECCS) and Direct Air Carbon Capture and Storage (DACCS). An online survey was conducted to examine how academic experts (N = 172) perceive and to what extent they support BECCS and DACCS. Overall, the results show rather high expert support for research on and the deployment of BECCS and DACCS. Perceived feasibility of the technologies consistently predicted support for BECCS and DACCS, with means in the upper medium range. Further significant predictors were the extent to which experts perceived the technologies to be necessary, the experts’ amount of academic experience, the associated moral hazard, and the perceived tampering with nature.