bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enjuagues bucales con carbohidratos y su uso en deportistas. Resumen de revisiones sistemáticas (Carbohydrate mouthwashes and their use in athletes. Overview of systematic reviews)
Authors: Fuentes-Barría Héctor , Aguilera-Eguía Raúl , González-Wong Catalina 
Published: January 2023

Objetivo; Analizar los efectos del enjuague bucal con carbohidratos en deportistas. Material y Métodos; Se realizó una búsqueda en la revista Retos, además de Medline / PubMed, Web of Science, Springer, Scopus, Europe PMC, SPOLIT, SPORTDiscus, SciELO, Epistemonikos y Trip database. Las búsquedas se realizaron entre los años 2018 y 2022 utilizando la estrategia “carbohydrate AND mouth rinse AND sports”, seleccionándose solo revisiones sistemáticas con metaanálisis. Resultados; Se identificaron 318 registros de los cuales luego de aplicar los criterios de elegibilidad se analizaron tres, cuyos resultados mostraron posibles mejoras sobre la potencia media de salida (Diferencia media estandarizada (DME) = 0,25, IC 95%; 0,04 a 0,46), rendimiento deportivo (DME = 0,15, IC 95%; 0,04 a 0,27) y la resistencia muscular hasta el fallo (Diferencia media (DM) = 1,24, IC 95%; 0,70 a 1,77), mientras que el tiempo contrarreloj (DME = -0,13, IC 95; -0,36 a 0,10) y la fuerza máxima muscular (DM = 0,25, IC 95%; -1,81 a 2,32) no muestran mejoras significativas. Conclusión; La suministración de un protocolo de enjuagues bucales con carbohidratos en forma constante puede constituir una ayuda ergogénica. Sin embargo, estos efectos aún son controvertidos.
Palabras clave: Suplementos dietético; carbohidratos; enjuague bucal; rendimiento deportivo; medicina deportiva.
Abstract. Objective; To analyze the effects of mouthwash with carbohydrates in athletes. Material and methods; A search was carried out in the journal Retos, in addition to Medline / PubMed, Web of Science, Springer, Scopus, Europe PMC, SPOLIT, SPORTDiscus, SciELO, Epistemonikos and Trip database. The searches were carried out between the years 2018 and 2022 using the strategy "carbohydrates AND mouthwash AND sports", selecting only systematic reviews with meta-analysis. Results; 318 records were identified, of which after applying the eligibility criteria, three were analyzed, which results showed possible improvements on the mean power output (Standardized Mean Difference (SMD) = 0.25, 95% CI; 0.04 to 0 .46), athletic performance (SMD = 0.15, 95% CI, 0.04 to 0.27), and muscular endurance to failure (Mean Difference (MD) = 1.24, 95% CI, 0.70 to 1.77), while time trial (SMD = -0.13, 95% CI; -0.36 to 0.10) and maximum muscle strength (MD = 0.25, 95% CI; -1, 81 to 2.32) does not show significant improvements. Conclution; The administration of a protocol of mouth rinses with carbohydrates in a constant way could constitute an ergogenic aid. However, these effects are still controversial.
Keywords: Dietary supplements; carbohydrates; mouthwashes; athletic performance; sports medicine.
Mitigating Academic Institution Dropout Rates with Predictive Analytics Algorithms
Authors: Lainjo Bongs 
Published: January 2023

Multiple studies show student dropout rates across rich, low and middle-income countries. With the development of machine learning, various learning institutions have initiated predictive analytics algorithms to solve this issue. However, there is limited knowledge on how this strategy has been employed to optimize retention rates. The research aims to comprehensively review PAAs Strategies and demonstrate how they have been effectively implemented in optimizing retention rates with a case study focusing on North America. The study employed a quantitative research methodology and thematic study design to review the existing literature. The result shows that learning institutions used a combination of data mining classifiers such as k-Nearest Neighbor, Neural Networks, Decision Tree, and Naive Bayes to categorize student dropout rates and optimize retention rates. The PAAs approach has been utilized by various educational institutions across North America, applying multiple predicting algorithms to ensure efficiency.
Keywords: Predictive analytics algorithms, mitigating dropout rates, retention rates, classifiers, Learning institutions, North America
Pengembangan Soal Evaluasi Berbasis Game dengan Menggunakan Aplikasi Wordwall
Authors: Sholeh Muhammad , Hamzah Amir , Basuki Untung Joko , Susanto FX. Guntur Putra 
Published: January 2023

Penggunaan teknologi informasi dalam mendukung proses pembelajaran sudah menjadi salah satu kebutuhan yang harus dipersiapkan para guru. Guru harus menyesuaikan perkembangan teknologi informasi. Guru harus beradaptasi dan menyesuaikan dengan anak-anak yang lebih banyak menggunakan teknologi informasi dan lebih pintar dalam menggunakan smartphone. Banyak aplikasi yang dapat digunakan dalam mendukung proses pembelajaran berbasis teknologi infomasi. Salah satu aplikasi yang dapat digunakan dalam pembuatan soal online adalah dengan menggunakan aplikasi Wordwall. Tujuan dari kegiatan ini diantaranya memberikan alternatif kepada para guru dalam penggunaan aplikasi untuk membuat latihan soal online. Pemilihan aplikasi Wordwall dengan pertimbangan aplikasi tersebut mudah digunakan dan soal yang disajikan ke siswa dapat dipilih dalam bentuk permainan. Dengan mengemas dalam permainan diharapkan siswa merasa senang dalam mengerjakan soal. Metode dalam kegiatan dilakukan dengan memberikan pelatihan dan mempraktikkan secara langsung. Penggunaan metode praktik ini diharapkan para guru dapat langsung mengimplementasikan pembuatan soal. Hasil dari kegiatan ini, para guru mampu mengembangkan soal online dan membentuk luaran soal dengan berbagai bentuk permainan dan mendistribusikan soal ke siswa
A study on the utilization of Ayushman Bharat arogya scheme among patients admitted to a tertiary care hospital during Covid pandemic
Authors: Rao Amit Kumar , K Shrisharath , S Nanjesh Kumar , Hiremath Shivkumar , P Jagannath , S Erappa 
Published: January 2023

Introduction and Aim: In India, most of the households face financial hardships due to catastrophic health care expenses. In response to covid-19 pandemic, the government launched the Ayushman Bharat Arogya Karnataka program, which offered health insurance for the coverage of covid-19 treatment costs and prevent families from undergoing financial hardships and incurring healthcare costs. The purpose of this study was to investigate and compare the utilization of the Ayushman Bharat insurance scheme among covid-19 positive and non-covid patients admitted to a tertiary care hospital in the Karnataka district of Dakshina Kannada.

Methodology: Data was collected from medical records of a tertiary care hospital in the Dakshina Kannada District of Karnataka for this cross-sectional study. The data collected was analyzed using the Microsoft Excel program, and the results subjected to statistical analysis using IBM SPSS software ver.20.

Results: The study found that there was a significant association between utilization of ABArK among patients (Covid and non-Covid) admitted to the hospital. While the utilization of ABArK among covid patients was found to be 51.3%, the utilization among non-covid patients was only 14.1% (X2= 1242.32, p value <0.001).

Conclusion: To improve the utilization of this scheme, public awareness activities must be conducted. As a result, less out-of-pocket expenditure would be incurred and access to healthcare facilities made easier.
Association of prolactin and insulin with obesity in women with polycystic ovarian syndrome
Authors: K. Lavanya , N. Palaniappan , V.M. Vinodhini , Kumar K. Mahesh , Silambanan Santhi 
Published: January 2023

Introduction and Aim: Polycystic Ovarian Syndrome (PCOS) manifests with menstrual irregularities, infertility, galactorrhoea and hirsutism. Hormonal irregularities are found to be the pathogenesis behind PCOS. The study was aimed to evaluate whether obesity is associated with serum prolactin and insulin levels in PCOS women.

Materials and Methods: This case control study was conducted in a tertiary care hospital in Chennai. Control group included 30 apparently healthy women and cases included 30 PCOS patients, diagnosis based on Rotterdam criteria. The individuals were of 20-40 years of age in both the groups. The serum prolactin and insulin were analysed by ELISA. The obtained data were checked for normality of distribution and subjected to statistical analysis. Receiver Operating Characteristics (ROC) curve was done. Statistical analyses were performed using SPSS version 16.0. P less than 0.05 was considered statistically significant.

Results: The median and interquartile range (IQR) of serum insulin were 11.5 (1.8-70) and 5 (1.8-44) mIU/L in cases and controls respectively. The cut-off level of insulin was 7.0 mIU/L. The median and IQR of serum prolactin were 12.5 (4.5-53.0) and 12 (3.5-20) ng/mL in cases and controls respectively. BMI was positively correlated with age of the participants and prolactin.

Conclusion: PCOS is prevalent among obese reproductive individuals. Insulin was markedly elevated in PCOS individuals. Insulin resistance alters levels of luteinizing hormone and sex hormone binging globulins. Hyperprolactinemia is associated with anovulation or oligoovulation, galactorrhoea and hirsutism. In obese PCOS women, prolactin and insulin could be diagnostic markers of PCOS.
Role of serum lipoprotein(a) and its gene polymorphisms in cardiovascular burden among Indians: Coincidental association or causal relationship?
Authors: Kulkarni Vineet , Shetty Sukanya , Bhandary Roopa , Chakraborty Anirban , K. Subramanya 
Published: January 2023

The increase in mortality rate due to coronary artery disease (CAD) is a major public concern among Indians. Smoking, obesity, type II diabetes are strong predisposing factors for CAD. However, the incidences of CAD in patients without these classical risk factors point to the need for identifying novel predictive biomarkers of CAD. The epidemiological studies conducted among European, African, Chinese populations, have demonstrated quite convincingly that Lipoprotein(a) is positively correlated with CAD. However, such studies are very few in the Indian context. It has been suggested that serum Lp(a) at levels more than 20mg/dL is independently associated with the risk of CAD among Indians, particularly in the young and immigrant population. Further, CAD subjects with comorbidities tend to have higher serum Lp(a) level compared to CAD subjects without any comorbidities. Genome wide association studies demonstrated that certain SNPs in the Lp (a) encoding gene (LPA), including rs10455872, rs3798220 and rs2266788 are more prevalent among Indians and are found to be strongly associated with CAD complications. Thus, based on the results of limited studies conducted in the Indian population so far, serum Lp(a) appears to be a strong and reliable risk factor for the development of CAD among Indians. However, the role of other factors like serum triglycerides, total cholesterol, homocysteine and CRP also need to be considered in determining CAD risk. The focus in this review is to highlight the recent studies on the role of Lp(a) in cardiovascular diseases in Indian population, particularly in the context of genetic polymorphisms.
Gastroprotective effects of Triticum aestivum Linn., extract on ethanol-induced gastric ulcer in Wistar rats
Authors: Susan Oomen Sainu , Fernandes Hilda , Holla Rajendra 
Published: January 2023

Introduction and Aim: Triticum aestivum (wheatgrass) is high in nutrient availability and antioxidant enzymes. It also functions as a detoxifier and aids in the rejuvenation of healthy cells. The current study sought to determine the gastroprotective impact of aqueous ethanolic extract of wheatgrass on the ethanol-induced gastric ulcer.

Materials and Methods: Wistar rats were given an oral dosage of 100% ethanol (1 ml/200g) to cause gastric ulcers. A reference medicine called omeprazole was given orally at dosages of 20 mg/kg body weight and 200 and 400 mg/kg of wheatgrass extract, respectively. Blood samples were taken an hour after ethanol administration, and the stomachs of deceased rats were then examined biochemically, macroscopically, and microscopically.

Results: The gastric ulcer index considerably decreased after taking wheatgrass extract orally, which showed a considerable attenuation of gastric ulcer. The serum level of TNF-? and the activity of the gastric MPO were both significantly enhanced by pre-treatment with wheatgrass extract. Furthermore, compared to the ethanol-induced group, wheatgrass pre-treatment dramatically boosted gastric levels of enzymatic and non-enzymatic antioxidants, including CAT, TAC, and GSH with concurrent reductions in MDA levels. Further evidence for these conclusions came from histopathology research, which showed that wheatgrass had a healing impact on the hemorrhagic shock brought on by ethanol poisoning.

Conclusion: Due to its propensity to decrease oxidative stress and gastric inflammation, wheatgrass extract may have gastroprotective effects on ethanol-induced stomach ulcers.
Extraction and characterization of nickel oxide nanoparticles from Hibiscus plant using green technology and study of its antibacterial activity
Authors: Al-saidi Muthana , Jaleel Ahmad Al-bana Read , Hassan Ekhlas , Laftaah AL-Rubaii Bahaa Abdullah 
Published: January 2023

Introduction and Aim: Nanomaterials are tiny particles varying in size from 1-100 nanometers with wide implications in the fields of medicine, biology, and pharmaceutical sciences. In this study, we aimed to extract Nickel oxide nanoparticles (NiO-NP) from the tropical hibiscus plant, and evaluate these nanoparticles for their structural features as well as study the antimicrobial activity of NiO-NPs against Gram-positive and Gram-negative bacteria.

Materials and Methods: NiO nanoparticles were synthesized by green nanotechnology using hibiscus extract and nickel nitrate as precursors. The NiO nanoparticles obtained were investigated for its surface properties using X-ray diffraction (XRD), Fourier transform infrared (FT-IR) spectroscopy and UV-Vis analysis. Transmission Electron Microscopy (TEM) was used in calculating the size of NiO nanoparticles. The antimicrobial activity of the NiO particles was tested against E. coli and S. aureus test strains.

Results: X-ray diffraction (XRD) and Fourier transform infrared (FT-IR) spectroscopy studies confirmed the formation of pure and well- crystallized NiO nanoparticles. The TEM analysis displayed that the size of nanoparticles to be within the limits of 71. The NiO-NP particles displayed antimicrobial properties and inhibited the growth of bacterial test strains used in this study.

Conclusion: The study demonstrated that nano Nickel oxide (NiO) particles could be successfully prepared using the hibiscus aqueous plant extract. The NiO-NP exhibited antimicrobial property against pathogenic E. coli and S. aureus bacteria, indicating that it could be used in formulations for treating infections by these organisms.
Green chili (Capsicum frutescens) ethanol extracts lowered triglyceride levels in rats fed with high-fat diet
Authors: Prawitha Pinatih Putu Teja , Ayu Dewi Ni Nyoman , Gede Sutadarma I Wayan 
Published: January 2023

Introduction and Aim: Cardiovascular diseases (CVDs) are the world’s leading cause of death. Capsaicinoids, naturally occurring alkaloids found in Capsicum peppers, have been shown to lower plasma lipids and prevent atherosclerotic plaque formation. The present study aimed to compare the efficacy between Capsicum frutescens ethanol extract and statins on improving lipid profile in rats fed with high-fat diet.

Materials and Methods: Twenty-five 3 months’ old rats weighing approximately 200 ±10 g were divided into five groups of five rats each: normal-fed (NF), high-fat diet fed (FF), high-fat fed with 10mg/kg BW Capsicum frutescens ethanol extract (FF-C), high-fat fed with 0.36 mg statin (FF-S), and high-fat fed with Capsicum extract and statin (FF-CS). The experimental period lasted 6 weeks. Blood sample was then collected and analyzed for serum total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C).

Results: Between treatment groups, there was a significant difference of TC and TG levels (p < 0.05). The high-fat diet increased TC (mean difference (MD) 35.0 ± 9.7 mg/dL, p = 0.022) and TG (MD 76.67 ± 21.8 mg/dL, p = 0.026) significantly between NF and FF group. The addition of Capsicum frutescens decreased triglyceride levels significantly between FF and FF-C group (MD -39.4 ± 18.8 mg/dL, p = 0.038). No other significant difference was found between other treatment groups.

Conclusion: The addition of Capsicum frutescens ethanol extract has shown to be effective in lowering triglyceride levels, but not other lipid profile parameters, among rats fed with high-fat diet.
Effect of Cymbopogon citratus on biofilm production by multidrug resistant Acinetobacter baumannii
Authors: Aquinas Natasha , Suman Ethel , B. Dhanashree , Hegde Ashwini 
Published: January 2023

Introduction and Aim: Acinetobacter baumannii, is the cause of many nosocomial infections which poses a serious threat to patients. Being a highly resistant organism, it has been placed in the critical priority list by WHO in 2017, thereby requiring newer effective drugs and alternative strategies. Increased antibiotic resistance has made it difficult to treat patients infected with this organism. The study aimed to find the biofilm forming ability of multidrug resistant A.baumannii causing respiratory tract infections, to find the genes responsible for biofilm production and to find the effect of Cymbopogon citratus (lemon grass) extract on biofilm.

Materials and Methods: The antibiogram profile was studied for the Acinetobacter isolates obtained from endotracheal aspirates, endotracheal tubing tips by antibiotic susceptibility testing and Vitek-2. Genes known to be associated with biofilm production, (AbOmpA, Bap) in Acinetobacter were detected by Polymerase chain reaction (PCR). The Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC), Minimum Biofilm Inhibitory Concentration (MBIC), Minimum Biofilm Eradication Concentration (MBEC) of Cymbopogon citratus essential oil was determined by microtiter plate method.

Results: Isolates that were tested were found to be Multidrug resistant (MDR) and Extremely drug resistant (XDR) with highest resistance to Carbapenems (95.83%). Activity of Cymbopogon citratus EO was determined. The isolates predominantly showed MIC of 2% and MBC was 8%. MBIC was found to be 1%. However, Cymbopogon citratus EO did not eradicate the preformed biofilms. All 24 isolates showed AbOmpA gene and six showed presence of Bap gene.

Conclusion: This study demonstrated that isolates that produced the Bap gene were Extremely drug resistant (XDR). Biofilm formation was inhibited by Lemongrass essential oil (EO) but it did not eradicate the preformed biofilms.
Etiology, clinical and laboratory characteristics, and outcomes in patients with acute viral hepatitis
Authors: Ainura Kutmanova , Lira Imanbaeva , Aisuluu Buranchieva , Ainura Dzhangazieva , Mira Tursunbaeva , Gulkaiyr Zakirova , Tagaev Tugolbai , Vipin  
Published: January 2023

Introduction and Aim: Kyrgyzstan is one of the most focused countries in the WHO European Region for acute viral hepatitis. The objective of this study is to evaluate the etiology, clinical and laboratory characteristics, and outcomes in patients with acute viral hepatitis.

Materials and Methods: This is a prospective study conducted on 122 patients with acute viral hepatitis at our hospital from March 2017 to June 2020. The diagnosis of acute viral hepatitis was based on the standard case definition: sudden onset with symptoms of a) acute illness (fever, malaise, weakness); b) liver damage (anorexia, nausea, jaundice, dark urine, right upper quadrant tenderness); c) elevation activity of alanine aminotransferase is more than ten times compared to normal levels.

Results: One hundred and twenty-two patients with acute viral hepatitis, including hepatitis A virus - 44 (36.1%), hepatitis B virus - 45 (36.9%), hepatitis C virus - 11 (9.0%), unspecified etiology - 22 (18, 0%). Patients with unidentified hepatitis, diagnosed through anti-HSV IgG was detected in 19 (86.4%) cases, anti-EBV IgG was detected in 18 (81.8%) cases, and 14 (63.6%) patients with anti-CMV IgG were present.

Conclusion: This study demonstrates the need to consider herpes viruses in the differential diagnosis of patients with unspecified liver lesions.
Role of videolaparoscopy in the surgical treatment of hepatic cystic echinococcosis
Authors: Toktogaziev Bakyt , Aitbaev Siezbek , Abdiev Allan , Toktosunov Arsen , Rysova Aiperi , Imankulov Mikhail , Yethindra Vityala , Kanteti Krishna Priya 
Published: January 2023

Introduction and Aim: Cystic echinococcosis (CE) is the most common parasitic disease in Kyrgyzstan, which can affect all organs and organ systems of the body, but its most common localization is the liver and lungs. This study aimed to describe the possibilities and main stages of videolaparoscopy in the surgical treatment of hepatic CE.

Materials and Methods: Twenty-five patients aged 17-64 years who were under observation were admitted to the surgical department of our hospital from 2018-2022, were diagnosed with hepatic CE, and underwent surgical treatment by videolaparoscopy.

Results: The variant of the surgical technique was based on the use of three trocars including paraumbilical (basic – 10mm), epigastric (introduction and removal of a rubber sac with a chitinous sheath – 10 mm), and hypochondrium (on the right – 5mm). Only in three cases, it became necessary to include the 4th trocar mesogastric (on the right – 5mm), as demonstrated. The operation duration was 60±5 minutes. Drainage in the abdominal cavity was installed according to the location of the cavity and removed for 2-3 days.

Conclusion: Laparoscopic methods of treatment of hepatic CE provide greater efficiency when performed with proper surgical manipulations by considering the size and localization of cysts.