bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of AirAngel® vs Storz® videolaryngoscope and Macintosh® laryngoscope for endotracheal intubation training: Prospective randomized crossover study
Authors: Merter Şeyhmus , Kayayurt Kamil , Kitapçıoğlu Dilek , Yaylaci Serpil 
Published: September 2023

Abstract

Background: Video laryngoscopy (VL) outperforms direct laryngoscopy (DL) in both normal and difficult airway situations. However, VL seems far from being offered as a standard option in both healthcare delivery and educational activities in low-income countries, considering its high costs. Therefore, three dimensional (3D)-printed VLs may be considered an alternative to conventional VLs in low-income countries and other places with limited resources. Our objective was to compare the efficacy of AirAngel 3D-printed VL (3D-PVL) with those of commercially available Storz® VL (SVL) and conventional Macintosh® laryngoscope (MCL) in normal and difficult airway scenarios in the hands of inexperienced users.
Methods: This is a prospective randomized crossover manikin study that included 126 senior medical students with no experience in intubation. The effectiveness of all three laryngoscopy devices in the hands of inexperienced users was evaluated in terms of intubation time, glottic visualization, ease of use, endotracheal tube placement and intubation success rate. Between 2020 and 2022, 126 last year medical students participated in the study.
Results: MCL resulted in significantly longer intubation times than 3D-PVL and SVL in the difficult airway scenario, with no significant difference between 3DPVL and SVL (Wilcoxon test, p < 0.016; Bonferroni correction MCL: 28.54 s; SVL: 26.68 s; 3DPVL: 26.64 s). Both SVL and 3D-PVL resulted in significantly better Cormack−Lehane grades in both normal and difficult airway scenarios, and thus provided better glottic viewing than MCL, with no significant difference between 3D-PVL and SVL (Wilcoxon test, p < 0.016; Bonferroni correction, MCL: 1.73; SVL: 1.29; 3DPVL: 1.25). SVL was the easiest (1: very easy, 5: very difficult) device for normal airway scenarios, while MCL was the most difficult (MCL: 2.64; 3DPVL: 1.98; SVL: 1.49). Conversely, no significant difference was found between 3DPVL and other devices in terms of ease of use in difficult airway scenarios and in terms of accurate placement of the endotracheal tube and successful intubation attempts.
Conclusion: 3D-PVL is a good educational and possible clinical alternative to conventional VL, particularly in places with limited resources, due to its low cost.
Development of a novel cancer survivorship database to describe health care utilization patterns for Coloradans who have completed primary cancer treatment
Authors: Callaway Carlin , Molina Elizabeth , Overholser Linda , Das Santi 
Published: September 2023

Abstract
Purpose Electronic health records (EHR) and data warehouses hold promise for population health management. Specific aims were: (a) to build a comprehensive database representing adult Coloradans who completed cancer treatment within a health care system, and (b) to conduct a secondary analysis of this database.Methods A survivorship database (HDC-SD) was built from the Health Data Compass (HDC) warehouse, which includes diagnostic and treatment information and incorporates all-payer data to identify individuals with histories of cancer who received treatment at the University of Colorado Cancer Center (UCCC) between January 1, 2020 and December 31, 2021. Data was analyzed using Chi-square tests to compare sociodemographic characteristics, disease characteristics, and health maintenance between urban and rural settings.Results The HDC-SD includes 1933 records representing 13 categories of cancers. The majority live in an urban setting (89.8%). Patients in the database living in urban areas had statistically (higher/lower) rates of completing colorectal screening, mammography, flu shots, and COVID-19 vaccination. Emergency department visits occurred at a statistically significant (higher/lower) level for those living in urban areas.Conclusions Creating a database of individuals who have completed active cancer treatment, while incorporating longitudinal health utilization data, may help prepare for systematic population management for cancer survivors.
Effects of pain associated with orthodontic tooth movement on tactile sensation of periodontal ligaments
Authors: Shimada Eriya , Kanetaka Hiroyasu , Hihara Hiroki , Kanno Akitake , Kawashima Ryuta , Nakasato Nobukazu , Igarashi Kaoru 
Published: September 2023

Abstract

Objectives Pain associated with orthodontic tooth movement reportedly reduces periodontal ligament tactile sensation. However, the mechanism at the central nervous system remains unclear. This study was designed to clarify the effects of pain associated with orthodontic tooth movement on periodontal ligament tactile sensation by measuring somatosensory evoked magnetic fields (SEFs) during mechanical stimulation of teeth being moved by separator elastics.
MethodsSEFs were measured using magnetoencephalography during the application of mechanical stimulations to the mandibular right first molars of 23 right-handed healthy subjects (0 hr). Separator elastics were then inserted into the mesial and distal interdental portions of the mandibular right first molars. The same mechanical stimulations were applied to them again 24 hr later. Then the SEFs were measured (24 hr). After each SEF measurement, pain was also evaluated using the Visual Analog Scale (VAS).
Results The VAS values were significantly higher at 24 hr than at 0 hr (p<0.05). Although no significant difference in the peak latencies was found between those obtained at 0 hr and 24 hr, the intensities around 40.0 ms in the contralateral hemisphere were significantly lower at 24 hr than at 0 hr (p<0.01).
ConclusionsPain associated with orthodontic tooth movement might suppress periodontal ligament tactile sensation in the primary somatosensory cortex.
Clinical Relevance Pain associated with orthodontic tooth movement might affect periodontal ligament sensation, consequently causing discomfort during occlusion.
Genome-Wide Identification and Drought stress-induced expression analysis of the Hsp90 gene Family in Potato
Authors: Ji yihong , Zhang Ning , Shao Ziying , Suo Meiqin , Wang Lei 
Published: September 2023

Abstract

Heat shock proteins play important roles in regulating plant growth and development and participating in response to abiotic stresses. However, the role ofHsp90gene family in potato (Solanum tuberosum L.) is yet to be known. In the present study, 9StHsp90s were identified in the potato genome. They were unevenly distributed on 7 chromosomes. Phylogenetic analysis divided theStHsp90s into four subfamilies (Class I–V). Real-time quantitative reverse transcriptase–polymerase chain reaction (RT-qPCR) results detected that 9StHsp90s responded differently to drought stresses. Three genes(PG0022159,PG1006147andPG0019647)had the higher relative expression level than other genes in flowers, which were 9, 16 and 17 times than that in roots, respectively, suggesting their involvement in tissue-specific pattern. This study presents a comprehensive overview of the potatoHsp90gene family and lays a foundation for further analysis of theStHsp90functions on plant development and stress response.
The effect of transcranial direct current stimulation (tDCS) on cognitive function recovery in patients with depression following electroconvulsive therapy (ECT): protocol for a randomized controlled trial
Authors: Hu Renqin , Li Junyao , Lu Yulin , Luo Huirong , Zhang Yinlin , Wang Xueqian , Zhang Zheng , Luo Qinghua 
Published: September 2023

Abstract
Background
Electroconvulsive therapy (ECT) is a highly effective treatment for depressive disorder. However, the use of ECT is limited by its cognitive side effects (CSEs), and no specific intervention has been developed to address this problem. As transcranial direct current stimulation (tDCS) is a safe and useful tool for improving cognitive function, the main objective of this study was to explore the ability to use tDCS after ECT to ameliorate the cognitive side effects.
Methods
Forty-eight eligible participants will be recruited within two days after completing ECT course and randomly assigned to receive either active or sham stimulation in a blinded, parallel-design trial and continue their usual pharmacotherapy. The tDCS protocol consists of 30-min sessions at 2 mA, 5 times per week for 2 consecutive weeks, applied through 15-cm2 electrodes. An anode will be placed over the left dorsolateral prefrontal cortex (DLPFC), and a cathode will be placed over the right supraorbital cortex. Cognitive function and depressive symptoms will be assessed before the first stimulation (T0), after the 5th stimulation (T1), after the final stimulation (T2), 2 weeks after the final stimulation (T3), and 4 weeks after the final stimulation (T4) using the Cambridge Neuropsychological Test Automated Battery (CANTAB).
Discussion
We describe a novel clinical trial to explore whether the administration of tDCS after completing ECT course can accelerates recovery from the CSEs. We hypothesized that the active group would recover faster from the CSEs and be superior to the sham group. If our hypothesis is supported, the use of tDCS could benefit eligible patients who are reluctant to receive ECT and reduce the risk of self-inflicted or suicide due to delays in treatment. Otherwise, the results may indirectly suggest that cognitive impairment may be associated with ECT-induced prefrontal hypometabolism and hypoperfusion.
Trial registration details
The trial protocol is registered with https://www.chictr.org.cn/ under protocol registration number ChiCTR2300071147 (date of registration: 05.06.2023). Recruitment will start in November 2023.
Climatic Zoning of Yerba Mate and Climate Change Projections: A CMIP6 Approach
Authors: Torsoni Guilherme Botega , APARECIDO LUCAS EDUARDO DE OLIVEIRA , Lorençone Pedro Antonio , Lorençone João Antonio , de Lima Rafael Fausto , Rolim Glauco de Souza 
Published: September 2023

Abstract
Yerba mate (Ilex paraguariensis) has several nutritional and pharmaceutical properties and is traditionally used in South America in the preparation of various types of beverages. The pharmaceutical industry has a large number of patents for products related to the properties of this plant. This study aims to analyze the climatic zoning of the yerba mate relative to climate change using CMIP6 model projections. Understanding the potential effects of climate change on yerba mate production and distribution is essential due to its economic and cultural importance. The CMIP6 model allows the analysis of future scenarios by identifying favorable and unfavorable areas for cultivation. The results provide subsidies for adaptation and mitigation measures, helping in strategic planning and decision-making related to sustainable yerba mate production. This study aimed to identify favorable areas for Ilex paraguariensis cultivation for the main producing countries, that is, Brazil, Argentina, Paraguay, and Uruguay, under the CMIP 6 climate change scenarios. The study was conducted in producing regions of the North, Northeast, Midwest, Southeast, and South of Brazil and the countries Paraguay, Argentina, and Uruguay. The ideal air temperature for crop development ranges from 21 to 25°C and the ideal precipitation is > 1200 mm per cycle. Daily air temperature and precipitation data for the current scenario were collected using the WorldClim version 2 platform. Projections of future climate variables were obtained from the WorldClim 2.1 platform using the IPSL-CM6A-LR model, with a 30-second spatial resolution. Four shared socio-economic pathway scenarios were considered for four different periods: 2021–2040, 2041–2060, 2061–2081, and 2081–2100. Data from a geographic information system were used to carry out spatial interpolation throughout the Brazilian territory, using the Kriging method. The results showed that most of the studied territory is classified as unfavorable for yerba mate cultivation, with only 12.25% (1.5 million km2) considered favorable. The highest concentration of favorable areas is found in the South of Brazil and Uruguay, which are currently the main producers of yerba mate. Most future scenarios of climate change showed a high impact on the climate due to an increase in the mean air temperature and a reduction in precipitation, leading to possible negative impacts on yerba mate cultivation, with a total reduction of favorable areas in producing regions.
Retrospective multicentric comparison of Out-of-specification and Standard-of-care Tisagenlecleucel infusion for Diffuse Large B-cell Lymphoma
Authors: Santoro Armando , De Philippis Chiara , Zucchinetti Cristina , Mannina Daniele , Krampera Mauro , Zinzani Pier Luigi , Chiappella Annalisa , Rocco Alice Di , Orciuolo Enrico , Tisi Maria Chiara , Pistolese Flavio , Giordano Laura , Bramanti Stefania 
Published: September 2023

Abstract

Tisagenlecleucel (Tisa-cel) is an autologous anti-CD19 CAR T-cell that requires a complex manufacturing process. A product with all the quality criteria is acknowledged as “standard-of-care” (SOC), while the ones not fitting the benchmark are considered “out-of-specification” (OOS). This retrospective multicentric study compares the efficacy and safety outcomes of OOS Tisa-cel and SOC products. We enrolled a total of 44 DLBCL patients who underwent the treatment according to Italian Medicines Agency criteria. Among them, 11 received OOS Tisa-cel. After a median follow-up of 19.1 months (range, 0.7–43.9), one-year PFS was 45.5% and 36.4% (p = 0.899) and one-year OS was 47.7% and 55.7% (p = 0.598) for OOS and SOC patients, respectively. CRS occurred in 63.6% of patents in the OOS group vs 81.2% in the SOC group (p = 0.248), grade > 2 CRS in 0% vs 3% (p = 1) and ICANS in 3% vs 9% (p = 0.451), respectively. No patients developed grade > 2 ICANS. No cases of non-relapse mortality have been reported. Our data show that OOS infusion does not increase toxicity and has comparable outcomes to SOC products, suggesting to pursue this option in the absence of therapeutic alternatives. However, larger studies of OOS criteria effect on clinical outcomes are needed.
“Boys Love Boy Toys”: A Qualitative Study Exploring the Role of Fathers in Young Boys’ Gendered Toy Preferences
Authors: Tesolin Julia 
Published: September 2023

Abstract

Early childhood is an especially important period for children’s acquisition of gender related attitudes and beliefs. For boys, fathers serve as one of the primary social influences through which they learn about common gender stereotypes, including gender-typical and cross-gender play. The current qualitative study was conducted with six boys (ages 4–6) and their fathers (ages 34–37), where fathers were first asked to complete an adapted version of the Child-Rearing Sex-Role Attitude Scale, which assessed their attitudes and beliefs about gender related toys, activities, and behaviors. Semi-structured interviews were conducted with the father-son pairs, or with the boys alone, where they participated in a series of toy-preference activities. Descriptive coding and content analysis were used to analyze the responses boys provided for their choices of toys. Responses indicated that boys have a more stereotyped definition of “girl toys” than they do of “boy toys”. Fathers’ self-described beliefs reported on the Sex-Role Attitude Scale were similarly reflected in their behaviours and comments during the interviews with their sons.
Offshore Wind and Wave Energy Can Reduce Total Installed Capacity Required in Zero Emissions Grids
Authors: Gonzalez Natalia , Serna-Torre Paul , Sanchez-Perez Pedro , Davidson Ryan , Murray Bryan , Staadecker Martin , Szinai Julia , Wei Rachel , Kammen Daniel , Sunter Deborah , Hidalgo-Gonzalez Patricia 
Published: September 2023

Abstract

As countries around the world race to decarbonize their power systems in an effort to mitigate climate change, the body of research analyzing paths to zero emissions electricity grids has substantially grown. Although many commercially available technologies are typically included in these studies, only a few of them have considered offshore wind and wave energy as contenders in future zero emissions grids. We model, for the first time, offshore wind and wave energy as independent technologies with the possibility of collocation in a power system capacity expansion model of the Western Interconnection with zero emissions by 2050 and a high geographical and temporal resolution. Our key contributions are to identify cost targets for offshore wind and wave energy to become cost effective, to observe a 17% of reduction in total installed capacity by 2050 when offshore wind and wave energy are fully deployed, and to show how total curtailment decreases as offshore wind increases its deployment.
Evaluation of Ovarian Reserve in Unexplained Infertile Cases : A case controlled study
Authors: Sahin Mustafa , Guven Suleyman , Sal Hidayet , Guven Emine Seda Guvendag 
Published: September 2023

Abstract
Background
The aim of this study was to evaluate the effectiveness of current ovarian reserve tests in unexplained infertile cases.
Material And Methods
This case-control study was conducted on 70 unexplained infertile women were included in Tertiary Iniversity hospital. Both groups of basal FSH, estradiol, Antimullerian hormone (AMH), inhibin B, ovarian volume, total antral follicle count (AFC), ovarian volume, ovarain stromal blood flow (Peak systolic velocity (PSV), S/D (systole and diastole ratio), Resistance index (RI) and pulsatility index (PI)) values were compared.
Results
The mean AMH, inhibin B, PSV and stromal blood flow values of the control group patients was higher than those in unexplained infertility group. However, the values of means of RI and PI of the cases in the control were lower than those in infertility group. When PI's value was ≥ 2.00, its sensitivity was 65.7%, and its specificity was 64.3%. In case of the RI's value was ≥ 0.745, its sensitivity was 65.7%, and its specificity was 62.9%. In order to show ovarian reserve in unexplained infertile cases, the sensitivity values can be sorted from high to low as follows : PI > RI > estradiol > FSH > ovarian volume > AFC > inhibin B > stromal blood flow > PSV > S/D.
Conclusion
In the unexplained infertile patient group with a normal ovarian reserve test results, basal estradiol, decreased PI and RI values may be used as goog ovarian reserve predictors.
Uniform stability for a semilinear laminated Timoshenko beams posed in inhomogeneous medium with localized nonlinear damping
Authors: Mansouri Sabeur 
Published: September 2023

Abstract

This paper is mainly concerned with the stabilization of a semilinear laminated Timoshenko beams, posed in an inhomogeneous medium, under the actionof three nonlinear localized frictional damping terms. Such a problem consists of two identical layers of uniform thickness, taking into account that an adhesive of small thickness is bonding the two surfaces and produces an interfacial slip. The main objective is to prove the uniform decay rates for the energy of the considered problemby imposing minimal amount of support for the damping and with no restrictions around the non-constant coefficients. The proof of the desired result is based on some techniques of the Microlocal Analysis Theory.
Effect of physical activity education on shoulder girdle pain and muscle strength in participants with fibromyalgia: an experimental study
Authors: Couëpel Bastien , Daneau Catherine , Tremblay Mathieu , Javelot Thomas , Abboud Jacques , Pagé Isabelle , Descarreaux Martin 
Published: September 2023

Abstract

Background
In patients with fibromyalgia, exercise and education are recommended to decrease pain level and improve pain management. The latest scientific evidence recommends to focus interventions on the upper limb. The aim of this study was to compare the immediate effect of physical activity education with control group on pain and muscle capacity during repeated upper limb contractions in participants with fibromyalgia.
Method
Fifty-six participants with fibromyalgia were randomized into an experimental group and a control group. The intervention consisted in watching a five-minute video that provided information about fibromyalgia, pain, kinesiophobia and physical activity. The control group watched a neutral five-minute video about beavers in Quebec. Following the video, participants performed a muscular fatigue task consisting in a repeated unilateral shoulder abduction task. At baseline and following the muscular fatigue task, maximal voluntary contraction (MVC) in shoulder abduction was assessed as well as pain level and pressure pain threshold (PPT) in the upper limb. Electromyographic activity was also assess for upper trapezius and middle deltoid muscles. Two-way repeated measures analysis of variance was used to compare the MVC, PPT, and pain level before and after the muscular fatigue task between groups.
Results
The experimental group showed a significantly lower increase in pain than the control group in the middle deltoid muscle (p = 0.002) when assessed by verbal pain rating scale. No significant interaction or main effect of Group and Time were observed for the pain level at the upper trapezius and elbow extensor muscles nor for any of the PPT measures. According to electromyographic data, the median frequency values indicate that neither group experienced muscle fatigue during the repeated contraction task.
Conclusions
The results suggest that a short physical activity education video positively influenced middle deltoid pain following repeated abduction in participants with fibromyalgia. Electromyographic analysis showed no evidence of objective muscle fatigue, suggesting that there might be a partial disconnection between the perception of muscle fatigue and the physiological biomarkers associated with muscle fatigue.
Composition of volatiles of citrus varieties and their effects on the behavior of Diaphorina citri
Authors: Oliveira Leanderson , Mesquita Paulo Roberto Ribeiro , Rodrigues Frederico Medeiros , Barbosa Cristiane Jesus , Fancelli Marilene , Costa João Gomes , Schnadelbach Alessandra Selbach 
Published: September 2023

Abstract
Currently, Huanglongbing (HLB) is the most devastating citrus disease in the world. Until the moment, there is no resistant variety to the disease pathogens and the management of the disease includes the chemical control of the insect vector, the Asian citrus psyllid Diaphorina citri (ACP). The goal of this study was to identify the attractiveness of citrus varieties to ACP using a four-arm olfactometer and to identify the volatile organic compounds emitted by the analyzed plants. The following varieties were used: 'Valencia', 'Westin' and 'Pera' sweet orange scions, also the rootstocks, 'Rangpur lime', 'Sunki Tropical', and 'HTR059' hybrid. The VOCs were extracted using the SPME technique and identified through GC-MS. 'Sunki Tropical', 'Rangpur lime' and 'Valencia' were more attractive to D. citri than the others varieties. The main compounds found in the least attractive varieties were β-pinene and linalol in 'Pera', β-pinene and decanol in 'Westin', β-caryophyllene and γ-elemene in 'HTR 059'. Therefore, 'HTR 059', 'Pera' and 'Westin' are the varieties indicated to implement actions to prevent the introduction and spread of the disease. 'Valencia', 'Sunki Tropical' and 'Rangpur lime' are the least suitable varieties for cultivation when HLB prevention is required.