bluuebunny/crossref_metadata_2025_split huggingface dataset:
АКТИВАЦИЯ ЦЕМЕНТНОЗОЛЬНОШЛАМОВОГО ВЯЖУЩЕГО МЕТОДОМ КОМПЛЕКСНОЙ ЭЛЕКТРОМЕХАНИЧЕСКОЙ АКТИВАЦИИ
Authors: ДЖУМАБАЕВ М.Д. , МАХАМБЕТОВА У.К. , ЖАРЫЛГАПОВ С.М. , ДЖУМАБАЕВА К.М. 
Published: February 2023

Мақалада тұтқыр заттектің бөлшегін қосымша активтенуіне бір мезгілде әсер етуші факторлар, КЭМА ұстанымы, КЭМА эффектін жүргізуге арналған арнайы құрылымдағы зертханалық диірмені, шар диірменінің жаңартылған құрылымы, жаңартылған диірменнің жұмыс ұстанымы, кешенді электромеханикалық активтендірілген байланыстырғыш қоспаның құрамы, байланыстырғышты кешенді электромеханикалық активтендіру кезінде цементтікүлдішламды ерітінді байланыстырғышының активтендіру механизмі, барабанды электрополяризация диірменінде ұсынылған тәсілмен қосымша ұнтақталған цемент үлгілерін сынау нәтижелері, электрокоагуляция процесінде байланыстырғыштың дисперсті бөлшектерінің поляризациясы және өзара тартылуы, тұтқыр заттектің бөлшектері мен судың шекарасында иондардың қос электр қабатының (ҚЭҚ) пайда болуының әсері, ұсынылған құрылғыда шикізат компоненттерінің тұтқырлық қасиеттерін арттыру шарттары, әр түрлі активация түрлерімен активтендірілген қоспаның ζ - электрокинетикалық потенциалын өлшеу нәтижелері келтірілген.
В статье описаны факторы, влияющие одновременно на дополнительную активацию частицы вяжущего вещества, принцип КЭМА, лабораторная мельница специальной конструкции для проведения эффекта КЭМА, обновленная конструкция шаровой мельницы, принцип работы обновленной мельницы, состав комплексной электромеханически активированной вяжущей смеси, механизм активации цементнозольношламового вяжущего при комплексной электромеханической активации вяжущего, результаты испытаний образцов цемента на барабанной электрополяризационной мельнице предложенным способом, поляризация и взаимное притяжение дисперсных частиц вяжущего в процессе электрокоагуляции, влияние образования двойного электрического слоя ионов (ДЭС) на границе частиц вяжущего вещества и воды, условия повышения вяжущих свойств компонентов сырья в предлагаемом устройстве, полученные результаты по измерению ζ - электрокинетического потенциала активируемой смеси при различных видах активации.
This article describes the factors that simultaneously affect the additional activation of the binder particle, KЭMA principle, a laboratory mill of special design for carrying out the KЭMA effect, the updated design of the ball mill, the principle of operation of the updated mill, the composition of the complex electromechanical activated binder mixture, the activation mechanism of a cement ash slurry binder during complex electromechanical activation of the binder, the results of testing cement samples on a drum electro polarization mill by the proposed method, polarization and mutual attraction of dispersed binder particles in the process of electrocoagulation, the effect of the formation of a double electric layer of ions (DES) at the boundary of the particles of the binder and water, conditions for increasing the binding properties of raw material components in the proposed device, the results obtained on the measurement of ζ - the electrokinetic potential of the activated mixture with various types of activation.
КӨМІРСУТЕКТЕРДІ ТАСЫМАЛДАУ САЛАСЫН ТҰРАҚТЫ ДАМЫТУ
Authors: ЕСТЕКОВА К.Ж. , ЕСТЕКОВА Г.Б. 
Published: February 2023

Транспортировка нефти является стратегически важным направлением стабилизации экономики республики Казахстан. Цель статьи – проведение стратегического анализа через оценку факторов, влияющих на развитие отрасли: изменение цены на нефть, тарифы на транспортировку нефти, изменение курса национальной валюты, доступ к современным технологиям, уровень оплаты отечественных и привлекаемых специалистов. Рассматриваемые проблемы отрасли позволят повысить эффективность развития.
Мұнай тасымалдау Қазақстан Республикасының экономикасын тұрақтандырудың стратегиялық маңызды бағыты болып табылады. Мақаланың мақсаты – саланың дамуына әсер ететін факторларды бағалау арқылы стратегиялық талдау жүргізу: мұнай бағасының өзгеруі, мұнай тасымалдау тарифтері, ұлттық валюта бағамының өзгеруі, заманауи технологияларға қол жеткізу, отандық және тартылатын мамандардың төлем деңгейі. Саланың қаралып отырған проблемалары даму тиімділігін арттыруға мүмкіндік береді.
Oil transportation is a strategically important direction of stabilization of the economy of the Republic of Kazakhstan. The purpose of the article is to conduct a strategic analysis through the assessment of factors affecting the development of the industry: changes in oil prices, tariffs for oil transportation, changes in the exchange rate of the national currency, access to modern technologies, the level of payment of domestic and attracted specialists. The considered problems of the industry will increase the efficiency of development.
ИСПОЛЬЗОВАНИЕ МОДЕЛИ MVC ПРИ СОЗДАНИИ ВЕБ-ПРИЛОЖЕНИЯ ДЛЯ РЕСТОРАНА НА PHP
Authors: МИРКАСИМОВА Т.Ш. 
Published: February 2023

Бұл мақалада MVC архитектуралық өрнегі интерактивті және динамикалық сайттарды құру үшін қолданылады. Тұрақты HTML парағы пайдаланушының әрекеттеріне қалай жауап беру керектігін білмейді. Екі жақты өзара әрекеттесу үшін динамикалық веб-парақтар қажет. MVC - бұл веб-қосымшаның динамикалық дамуын түсінудің кілті, сондықтан веб-әзірлеуші осы модельді білуі керек.
Для создания интерактивных и динамичных сайтов обычно используется архитектурный паттерн MVC. Статическая страница на HTML не умеет реагировать на действия пользователя. Для двухстороннего взаимодействия нужны динамические веб-страницы. MVC – ключ к пониманию разработки динамических веб-приложений, поэтому разработчику нужно знать эту модель.
The MVC architectural pattern is commonly used to create interactive and dynamic sites. A static HTML page does not know how to respond to user actions. Two-way interaction requires dynamic web pages. MVC is the key to understanding dynamic web application development, so a developer needs to know this model.
As-Syatibi Economic Thinking
Authors: Permani Intan , Iskandar Iskandar 
Published: February 2023

Berbicara tentang pemikiran As-Syatibi, dimana beliau mengagas konsep atau pemikiran tentang ekonomi dalam ruang lingkup produksi, konsumsi dan distribusi. metode yang digunakan dalam penelitian ini adalah metode kepustakaan. Metode ini menggunakan documenter yang bersumber dari literaratur seperti, jurnal, buku, makalah dan internet yang membahas tentang pemikiran As-Syatibi tentang ekonomi Islam. Landasan berpijak dari pada pemikiran As-Syatibi tentang ekonomi mengacu pada konsep Maqashid Syariah yang orientasinya melahirkan Maslahah Mursalah. Pemikiran As-Syatibi ini diyakini sangat ideal untuk diimplementasikan dimasa modern ini karena pemikiran dan gagasan tentang ekonomi terdahulu dirasa sudah sangat tidak relavan. Disamping mampu menjawab tantangan jaman, teori Maqashid syariah yang disandingkan dengan pemikiran ekonomi ini juga harus membawa perubahan yang positif terkhusus untuk individu muslim ketika berhadapan dan terlibat langsung dengan kegiatan ekonomi itu sendiri. Disisi yang lain, As-syatibi membagi kebutuhan dan memberikan pandangan bahwa kebutuhan itu harus bersandar pada skala prioritas yang dicocokan dengan masing-masing tingkatan kebutuhannya. Adapun yang menjadi tingkatan nilai-nilai dalam perspektif ekonomi, As-Syatibi membagi menjadi tiga, pertama Dharuryah.kedua, Hajjiyah. Dan yang ketiga Tahsiniyah.
The relationships between Stress, Dark Triad personality and utilitarian Moral Judgment
Authors: Martins Ana Teresa , Sobral Tiago , Jiménez-Ros Antonia María , Faísca Luís 
Published: February 2023

There is a growing evidence that stress affects cognitive and emotional processes underling decision making. However, according some authors, subclinical personality traits of the participants must be also considered in this relation between stress and moral decision. Our study examines whether stress affects moral decision-making according two different subclinical personalities. Forty undergraduate volunteers were previously distributed according their personality traits (Machiavellian; Narcissism and Normal) and randomly assigned to both conditions (stress vs. control). The stress induction was assessed with a self-reported questionnaire and with a measurement of heart rate. All participants performed a moral decision-making task in which every day moral dilemmas were described. The main results suggest that stress group made less utilitarian choices when compared to control group. Although machiavellian and narcissistic participants made more utilitarian decisions; the interaction between stress, personality and moral judgment did not reach significance. We conclude that stress induction predisposed participants to less utilitarian responses when faced to personal and impersonal moral dilemmas. We also suggested that subclinical personality (particularly narcissism) seems to be less permeable to stress; revealing the same moral utilitarian pattern in both experimental conditions.
Association between geriatric nutritional risk index and pathological phenotypes of IgA nephropathy
Authors: Gan Yangang , Li Jiajia , Wu Jianping , Zhang Rui , Han Qianqian , Li Zizhen , Yang Qiongqiong 
Published: February 2023

Background
IgA nephropathy (IgAN) is an immune disease related to oxidative stress and inflammation. It is the most common type of glomerulonephritis in the world and is the cause of chronic kidney disease and end-stage renal disease (ESRD). The Geriatric Nutritional Risk Index (GNRI) is a practical and uncomplicated method to assess the risk of morbidity and mortality, but its ability to assess IgAN is still unclear. Here, we evaluated the association between the GNRI and clinical and histologic findings of IgAN.

Methods
In a cross–sectional study, we included 348 biopsy-verified IgAN patients. The Oxford classification was used to analyze the pathological characteristics of the included patients. Based on previous studies, the participants were divided into two groups using a cutoff value of 92. Differences in clinicopathological indices between the two groups were compared. The correlation between the GNRI and the indicators was evaluated by using a bivariate correlation analysis. A binary logistic regression analysis was conducted to determine the factors associated with the crescent lesions in IgAN.

Results
In this study, 138 out of 348 patients (39.7%) had low GNRI scores (GNRI < 92). Patients in the low GNRI group tended to have a significantly lower body mass index; lower hemoglobin, serum albumin, serum IgG, and serum C3 levels; and higher 24-h proteinuria. The proportions of females, Oxford M1 and Oxford C1/2 were higher in the low GNRI group. The GNRI was positively correlated with body mass index (r = 0.57, P < 0.001), hemoglobin (r = 0.35, P < 0.001), serum albumin (r = 0.83, P < 0.001), serum IgG (r = 0.32, P < 0.001), and serum C3 (r = 0.26, P < 0.001) and negatively correlated with 24-h proteinuria (r = −0.36, P < 0.001) and the proportion of crescents (r = −0.24, P < 0.001). The GNRI scores and serum IgG levels were considered independent factors influencing the crescent lesions in IgAN.

Conclusions
The GNRI can reflect the severity of clinical and histologic phenotypes in IgAN patients. Lower GNRI and serum IgG levels may suggest an increased risk of crescent lesions and are potential markers for disease monitoring in IgAN.
Detection of Pulmonary Tuberculosis by Gene Xpert Method among HIV Patient in ART Center, Gadarif State, Sudan
Authors: Elbashir Salwa Abdelrahman Hamd , Abakar A. D. , Nour Bakri Y. M. 
Published: February 2023

Background: Tuberculosis (TB) is one of the most common and deadly infectious diseases in humans. Due to widespread poverty, inequity, and conflict, suboptimal health services in many countries, and the impact of the HIV/AIDS pandemic, TB/HIV co-infected patients frequently test negative for TB with direct microscopy, posing diagnostic challenges. Traditional HIV-associated TB diagnosis is complex, expensive, time-consuming, and technically demanding because it relies on conventional culture and drug susceptibility testing. The lengthy wait for results has disastrous consequences for patients who go undiagnosed or are diagnosed too late.
Objective: To detect the accuracy of gene X pert® MTB/RIF as a novel automated molecular tool to diagnose Mycobacterium tuberculosis in HIV patients.
Methods: A cross sectional study was conducted on 70 HIV patients suspected to have Mycobacterium tuberculosis and who were referred to the ART and Tuberculosis Centers at Gadarif state, from June 2022 to December 2022. Sputum samples were tested by two methods involved the Gene X pert (Cepheid, California, United States of America) and direct smear microscopy (SM) stained with ZN stain for detection of acid fast bacilli. Out of 70 sputum samples analyzed for acid fast bacilli, 50(71%) cases were positive using GeneXpert whereas the DM was positive only for 28 (4o %) of the cases. GeneXpert detected another 22 AFB positive cases. Therefore GeneXpert is more accurate. Sensitivity of the GeneXpert was calculated as 93% and the specificity was 43%. The majority of the patients who contributed to (SM) were found to be co-infected with HIV.
Conclusion: GeneXpert demonstrated two-time case detection rate compared to the sputum smear microscopy so the direct smear showed poor performance tool for evaluation of TB-HIV co-infection. Also The Gene X pert’s sensitivity was found to be high while the specificity was low. Although this was the case, the GeneXpert as compared to DM could greatly reduce false negatives and the wait on treatment initiation can be significantly shortened, minimising premature death and continued transmission.
Immediate Dentin Sealing for Indirect Bonded Restoration: Literature Review
Authors: Omar Sarah , Albelady Waad , Alharbi Yamam , Alzubaidi Tamadher , Shuailah Latifah 
Published: February 2023

Objectives: The purpose of this review was to elaborate on the role of the immediate dentinal sealing technique in reducing hypersensitivity after indirect bonded restoration placement.
Materials and Methods: A PubMed literature search was conducted using the search terms “immediate dentin sealing” AND “dual bonding technique” AND “resin coating technique” AND “prehybridization”. The search was restricted to studies published between 1 January 2010 and 1 November 2022. A total of 31 papers were found as a result of the PubMed search. After the exclusion of irrelevant or duplicated articles, 15 articles were included in this review.
Results: The results strongly indicate that the immediate dentine sealing technique (IDS) improves the bonding strength between indirect restoration and tooth as compared to conventional delayed dentinal seal.
Conclusions: IDS is a sealing adhesive technique that reduces post-cementation hypersensitivity and improves adhesion for indirect restoration, especially in those indirect restorations in which hypersensitivity is more common after cementation and retention are difficult to achieve such as porcelain laminated veneer.
Association of Treatment Strategies and Tumor Characteristics With Overall Survival Among Patients With Anaplastic Thyroid Cancer
Authors: Wu Shannon S. , Lamarre Eric D. , Yalamanchali Anirudh , Brauer Philip R. , Hong Hanna , Reddy Chandana A. , Yilmaz Emrullah , Woody Neil , Ku Jamie A. , Prendes Brandon , Burkey Brian , Nasr Christian , Skugor Mario , Heiden Katherine , Chute Deborah J. , Knauf Jeffrey A. , Campbell Shauna R. , Koyfman Shlomo A. , Geiger Jessica L. , Scharpf Joseph 
Published: February 2023

ImportanceSurvival outcomes for anaplastic thyroid cancer (ATC), the most aggressive subtype of thyroid cancers, have remained poor. However, targeted therapies and immunotherapies present new opportunities for treatment of this disease. Evaluations of survival outcomes over time with new multimodal therapies are needed for optimizing treatment plans.ObjectiveTo evaluate the association of treatment strategies and tumor characteristics with overall survival (OS) among patients with ATC.Design, Setting, and ParticipantsThis retrospective case series study evaluated the survival outcomes stratified by treatment strategies and tumor characteristics among patients with ATC treated at a tertiary level academic institution from January 1, 2000, to December 31, 2021. Demographic, tumor, treatment, and outcome characteristics were analyzed. Kaplan-Meier method and log rank test modeled OS by treatment type and tumor characteristics. Data were analyzed in May 2022.Main Outcomes and MeasuresOverall survival (OS).ResultsThe study cohort comprised 97 patients with biopsy-proven ATC (median [range] age at diagnosis, 70 [38-93] years; 60 (62%) female and 85 [88%] White individuals; 59 [61%] never smokers). At ATC diagnosis, 18 (19%) patients had stage IVA, 19 (20%) had stage IVB, and 53 (55%) had stage IVC disease. BRAF status was assessed in 38 patients; 18 (47%) had BRAF-V600E variations and 20 (53%), BRAF wild type. Treatment during clinical course included surgery for 44 (45%) patients; chemotherapy, 41 (43%); definitive or adjuvant radiation therapy, 34 (RT; 35%); and targeted therapy, 28 (29%). Median OS for the total cohort was 6.5 (95% CI, 4.3-10.0) months. Inferior OS was found in patients who did not receive surgery (hazard ratio [HR], 2.12; 95% CI, 1.35-3.34; reference, received surgery), chemotherapy (HR, 3.28; 95% CI, 1.99-5.39; reference, received chemotherapy), and definitive or adjuvant RT (HR, 2.47; 95% CI, 1.52-4.02; reference, received definitive/adjuvant RT). On multivariable analysis, age at diagnosis (HR, 1.03; 95% CI, 1.01-1.06), tumor stage IVC (HR, 2.65; 95% CI, 1.35-5.18), and absence of definitive or adjuvant RT (HR, 1.90; 95% CI, 1.01-3.59) were associated with worse OS.Conclusions and RelevanceThis retrospective single-institution study found that lower tumor stage, younger age, and the ability to receive definitive or adjuvant RT were associated with improved OS in patients with ATC.
Nerve‐Fiber‐Inspired Construction of 3D Graphene “Tracks” Supported by Wood Fibers for Multifunctional Biocomposite with Metal‐Level Thermal Conductivity
Authors: Zhang Xilin , Li Jingchao , Gao Qiang , Wang Zhijian , Ye Neng , Li Jianzhang , Lu Yonglai 
Published: February 2023

AbstractGiven the rapid developments in modern electronics, there is an urgent need for polymer composites with excellent heat‐dissipating capabilities to address the cooling problem of these devices. However, designing a highly thermally conductive polymer composite that can outperform metals and ceramics while also exhibiting high processability and low cost remains a challenge. Herein, inspired by the fibrous pathway of human nervous system, natural wood fibers (WFs) are used as the template and coated with graphene nanoplates (GNPs) via a simple electrostatic self‐assembly approach. Subsequent hot‐pressing process yields “core‐sheath” microstructured fibers, wherein the GNPs are compactly contacted face to face and arranged along the surfaces of the fibrous WF “cores”. This WF@G biocomposite consists of highly efficient 3D fibrous “tracks” for heat transmission, resulting in an extremely high thermal conductivity of 134 W (m K)−1, which is at par with those of many metals. It also exhibits several other desirable properties and functionalities, including high mechanical strength and excellent flame resistance as well as remarkable electromagnetic shielding and Joule heating performances, which has significant potential for use as a functional thermal management material (TMM). Hence, this study describes a simple yet scalable manufacturing technique for the development of advanced metal‐level biomass‐based TMMs.
Modulation of Macrophages by In Situ Ligand Bridging
Authors: Kim Seong Yeol , Thangam Ramar , Kang Nayeon , Hong Hyunsik , Kim Chowon , Lee Sungkyu , Son Subin , Lee Hyun‐Jeong , Tag Kyong‐Ryol , Min Sunhong , Jeong Daun , Hwang Jangsun , Kim Kanghyeon , Kim Dahee , Kim Yuri , Joo Jinmyoung , Kim Bong Hoon , Zhu Yangzhi , Park Sung‐Gyu , Song Hyun‐Cheol , Sun Wujin , Ahn Jae‐Pyoung , Jang Woo Young , Paulmurugan Ramasamy , Kim Hong‐Kyu , Kim Jong Seung , Kang Heemin 
Published: February 2023

AbstractExtracellular matrix (ECM) proteins containing cell‐attachable Arg‐Gly‐Asp (RGD) sequences exhibit variable bridging and non‐bridging in fibronectin‐collagen and laminin‐collagen complexes that can regulate inflammation, tissue repair, and wound healing. In this study, linking molecule‐mediated conjugation of 1D magnetic nanocylinders (MNCs) to material surfaces pre‐decorated with gold nanospheres (GNSs) is performed, thereby yielding RGD‐coated MNCs (RGD‐MNCs) over RGD‐coated GNSs (RGD‐GNSs) in a non‐bridging state. The RGD‐MNCs are drawn closer to the RGD‐GNSs via magnetic field‐mediated compression of the linking molecules to establish the bridging between them. Relative proportion of the RGD‐MNCs to the RGD‐GNSs is optimized to yield effective remote stimulation of integrin binding to variably bridged RGDs similar to that of invariably bridged RGDs used as a control group. Remote manipulation of the RGD bridging facilitates the attachment structure assembly of macrophages that leads to pro‐healing/anti‐inflammatory phenotype acquisition. In contrast, the non‐bridged RGDs inhibited macrophage attachment that acquired pro‐inflammatory phenotypes. The use of various nanomaterials in constructing heterogeneous RGD‐coated materials can further offer various modes in remote switching of RGD bridging and non‐bridging to understand dynamic integrin‐mediated modulation of macrophages that regulate immunomodulatory responses, such as foreign body responses, tissue repair, and wound healing.
A Bimetallic Metal–Organic‐Framework‐Based Biomimetic Nanoplatform Enhances Anti‐Leukemia Immunity via Synchronizing DNA Demethylation and RNA Hypermethylation
Authors: Song Yue , Zhang Lingxiao , Wang Yiqiao , Han Mingda , Wang Zhihua , Wang Ning , Shao Bingru , Li Runan , Cao Kunxia , Song Meiyu , Du Yangyang , Yan Fei 
Published: February 2023

AbstractEpigenetic‐alterations‐mediated antigenicity reducing in leukemic blasts (LBs) is one of the critical mechanisms of immune escape and resistance to T‐cell‐based immunotherapy. Herein, a bimetallic metal–organic framework (MOF)‐based biomimetic nanoplatform (termed as AFMMB) that consists of a DNA hypomethylating agent, a leukemia stem cell (LSC) membrane, and pro‐autophagic peptide is fabricated. These AFMMB particles selectively target not only LBs but also LSCs due to the homing effect and immune compatibility of the LSC membrane, and induce autophagy by binding to the Golgi‐apparatus‐associated protein. The autophagy‐triggered dissolution of AFMMB releases active components, resulting in the restoration of the stimulator of interferon genes pathway by inhibiting DNA methylation, upregulation of major histocompatibility complex class‐I molecules, and induction of RNA‐methylation‐mediated decay of programmed cell death protein ligand transcripts. These dual epigenetic changes eventually enhance T‐cell‐mediated immune response due to increased antigenicity of leukemic cells. AFMMB also can suppress growth and metastases of solid tumor, which was suggestive of a pan‐cancer effect. These findings demonstrate that AFMMB may serve as a promising new nanoplatform for dual epigenetic therapy against cancer and warrants clinical validation.