bluuebunny/crossref_metadata_2025_split huggingface dataset:
Incidence of and risk factors for suspected and definitive glaucoma after bilateral congenital cataract surgery: a 5-year follow-up
Authors: Wang Jinghui , Wu Xianghua , Wang Qiwei , Zhou Fengqi , Chen Hui , Chen Wan , Lin Duoru , Zhang Xiayin , Wang Ruixin , Chen Jingjing , Liu Zhenzhen , Lin Zhuoling , Li Xiaoyan , Li Jing , Han Ying , Liu Yizhi , Lin Haotian , Chen Weirong 
Published: February 2023

AimsTo report the incidence and associated risk factors for developing suspected and definitive glaucoma after bilateral congenital cataract (CC) removal with a 5-year follow-up.MethodsSecondary analysis of a prospective longitudinal cohort study. Bilateral CC patients who had undergone cataract surgery between January 2011 and December 2014 at Zhongshan Ophthalmic Centre were recruited. Suspected glaucoma was defined as persistent ocular hypertension requiring medical treatment. Definitive glaucoma was defined as accompanied by the progression of glaucomatous clinical features. According to postoperative lens status in 5 years follow-up: 130 eyes in the aphakia group; 219 in the primary intraocular lens (IOL) implantation group and 337 in the secondary IOL implantation group. The Kaplan-Meier survival and Cox regression analyses were used to explore the cumulative incidence and risk factors for suspected and definitive glaucoma.ResultsThree hundred fifty-one children (686 eyes) with bilateral CCs were enrolled in the study. The mean age at surgery was 1.82±2.08 years, and the mean follow-up duration was 6.26±0.97 years. Suspected and definitive glaucoma developed at a mean time of 2.84±1.75 years (range 0.02–7.33 years) postoperatively. The cumulative incidence of suspected and definitive glaucoma was 9.97% (35 of 351 patients), including 6.12% (42 eyes) for definitive glaucoma and 2.48% (17 eyes) for suspected glaucoma. Microcornea (HR 4.103, p<0.0001), CC family history (HR 3.285, p=0.001) and initial anterior vitrectomy (HR 2.365 p=0.036) were risk factors for suspected and definitive glaucoma. Gender, age at surgery, intraocular surgery frequency, length of follow-up and frequency of neodymium-doped yttrium aluminumaluminium garnet laser were non-statistically significant. Primary IOL implantation was a protective factor (HR 0.378, p=0.007).ConclusionsIdentifying suspected and definitive glaucoma after bilateral CC surgery can lower the risk of secondary blindness in children. Patients with related risk factors need to pay more attention and thus reach early intervention and treatment during clinical practice. Primary IOL implantation may be a potential protective factor, need more clinical trials to be verified.Trial registration numberNCT04342052.
Definition of age-dependent reference values for the diameter of the common bile duct and pancreatic duct on MRCP: a population-based, cross-sectional cohort study
Authors: Beyer Georg , Kasprowicz Florian , Hannemann Anke , Aghdassi Ali , Thamm Patrick , Volzke Henry , Lerch Markus M , Kühn Jens-Peter , Mayerle Julia 
Published: February 2023

ObjectiveChanges of the pancreaticobiliary ducts herald disease. Magnetic resonance cholangiopancreatography (MRCP) allows accurate duct visualisation. Data on reliable upper reference ranges are missing.DesignCross-sectional whole body MRI data from the population-based Study of Health in Pomerania were analysed. The width of the common bile duct (CBD) and the pancreatic duct (PD) was determined. We aimed to describe the distribution of physiological duct diameters on MRCP in a population of healthy subjects and to identify factors influencing duct size.ResultsAfter excluding pre-existing pancreaticobiliary conditions, CBD and PD diameters from 938 and 774 healthy individuals, respectively, showed a significant increase with age (p<0.0001) and exceeded the conventional upper reference limit of normal in 10.9% and 18.2%, respectively. Age-dependent upper reference limits of duct diameters were delineated with non-parametric quantile regression, defined as 95th percentile: for CBD up to 8 mm in subjects <65 years and up to 11 mm in subjects ≥65 years. For the PD reference diameters were up to 3 mm in subjects <65 years and up to 4 mm in subjects ≥65 years.ConclusionsThis is the first population-based study delineating age-adjusted upper reference limits of CBD and PD on MRCP. We showed that up to 18.2% of healthy volunteers would have needed diagnostic workup, if the conventional reference values were used. The utilisation of the adapted reference levels may help to avoid unnecessary investigations and thus to reduce healthcare expenditure and test-related adverse events.
Risk of myocardial infarction after invasive outpatient procedures
Authors: Sen Abhijit , Gémes Katalin , Svensen Christer , Varmdal Torunn , Jonsson Magnus , Janszky Imre , Möller Jette 
Published: February 2023

ObjectiveTo assess the short-term risk of acute myocardial infarction (AMI) associated with procedures performed at outpatient specialised hospital clinics.MethodsIn this case-crossover, population-based study, we identified first-time AMI cases aged ≥40 years via patient registries and linked them to their surgical intervention in Norway (2008–2016) and Sweden (2001–2014), respectively. The number of individuals with AMI who underwent procedures 0–7 days (hazard period) prior to the AMI diagnosis was compared with cases who were exposed 29–36 days (control period) before the AMI. A total of 6176 patients with AMI who underwent a procedure either during the defined hazard or control period contributed to the analyses. ORs with 95% CIs were computed using conditional logistic regression.ResultsThe mean age of the total population was 74.7 years and 64.6% were male. The relative risk was higher following procedures performed under general/regional anaesthesia for gastrointestinal endoscopy (ORsummary, 4.23, 95% CI 1.58 to 11.31), vascular (ORsummary, 3.12, 95% CI 1.10 to 8.90), urological/gynaecological (ORsummary, 2.30, 95% CI 1.50 to 3.53) and orthopaedic (ORsummary,1.78, 95% CI 1.30 to 2.44) procedures, and for ENT (ear, nose and throat) and mouth procedures (ORsummary,1.53, 95% CI 1.19 to 1.99) performed under local anaesthesia.ConclusionThis large population-based register study from two countries suggests that outpatient procedures are generally safe with regard to the postoperative risk of AMI. However, some procedures, such as gastrointestinal endoscopy, vascular procedures and urological/gynaecological procedures may increase the risk of AMI by twofold or threefold within the first 8 days after the procedures. Further studies are warranted to assess whether the effect is modified by cardiovascular medication or other clinical factors.
Predictive value of the TRI-SCORE for in-hospital mortality after redo isolated tricuspid valve surgery
Authors: Dreyfus Julien , Bohbot Yohann , Coisne Augustin , Lavie-Badie Yoan , Flagiello Michele , Bazire Baptiste , Eggenspieler Florian , Viau Florence , Riant Elisabeth , Mbaki Yannick , Eyharts Damien , Sénage Thomas , Modine Thomas , Nicol Martin , Doguet Fabien , Le Tourneau Thierry , Tribouilloy Christophe , Donal Erwan , Tomasi Jacques , Habib Gilbert , Selton-Suty Christine , Radu Costin , Lim Pascal , Raffoul Richard , Iung Bernard , Obadia Jean-Francois , Audureau Etienne , Messika-Zeitoun David 
Published: February 2023

ObjectivesThe TRI-SCORE reliably predicts in-hospital mortality after isolated tricuspid valve surgery (ITVS) on native valve but has not been tested in the setting of redo interventions. We aimed to evaluate the predictive value of the TRI-SCORE for in-hospital mortality in patients with redo ITVS and to compare its accuracy with conventional surgical risk scores.MethodsUsing a mandatory administrative database, we identified all consecutive adult patients who underwent a redo ITVS at 12 French tertiary centres between 2007 and 2017. Baseline characteristics and outcomes were collected from chart review and surgical scores were calculated.ResultsWe identified 70 patients who underwent a redo ITVS (54±15 years, 63% female). Prior intervention was a tricuspid valve repair in 51% and a replacement in 49%, and was combined with another surgery in 41%. A tricuspid valve replacement was performed in all patients for the redo surgery. Overall, in-hospital mortality and major postoperative complication rates were 10% and 34%, respectively. The TRI-SCORE was the only surgical risk score associated with in-hospital mortality (p=0.005). The area under the receiver operating characteristic curve for the TRI-SCORE was 0.83, much higher than for the logistic EuroSCORE (0.58) or EuroSCORE II (0.61). The TRI-SCORE was also associated with major postoperative complication rates and survival free of readmissions for heart failure.ConclusionRedo ITVS was rarely performed and was associated with an overall high in-hospital mortality and morbidity, but hiding important individual disparities. The TRI-SCORE accurately predicted in-hospital mortality after redo ITVS and may guide clinical decision-making process (www.tri-score.com).
From alchemy to personalised medicine: the journey of laboratory medicine
Authors: Verna Roberto 
Published: February 2023

This review summarises the long period in which man has approached nature to understand its powers, and has tried to control it through physical and chemical, and also magical, practices. From the attempt to manage nature to the development of primordial drugs and medical practices and later to achieve modern biomedical science, laboratory practices always played a pivotal role. Over the years and centuries, the laboratory has acquired more and more importance in the improvement of health.In addition to the well-known importance of laboratory medicine in the early diagnosis and appropriateness, the discoveries of the last 50 years have also given the Laboratory a decisive role in regenerative and personalised medicine.This paper examines the evolution of the laboratory and is not meant to be a treatise on the history of medicine. The goal is to highlight the moments of the transition from magic and alchemy to laboratory science.-------------------------------Roberto Verna is President of the World Association of Societies of Pathology and Laboratory Medicine and President of the Academy for Health and Clinical Research.
Occupational risk factors associated with lower urinary tract symptoms among female workers: a systematic review
Authors: Yoo Hyoungseob , Kim Jae Yoon , Lee Yu Min , Kang Mo-Yeol 
Published: February 2023

A systematic review was performed aiming to identify the various occupational risk factors of lower urinary tract symptoms (LUTS) among female workers. A systematic, comprehensive literature search of PubMed, Embase and Cochrane Library databases was conducted to identify studies published until 24 November 2021, evaluating the possible occupational risk factors of LUTS among female workers. Two reviewers assessed all articles retrieved through a computerised search for eligibility using predetermined criteria. Data on the first author, publication year, country, study design, participants, identified occupational risk factors, outcome variables and main results were extracted from the selected articles. The Newcastle–Ottawa Quality Assessment Scale guidelines were adopted to estimate the quality scores. Overall, our search yielded a total of 16 articles suitable for review. The occupational risk factors identified in the studies were strenuous physical demand and activity, prolonged sitting, occupational stress, shift work, limited use of the toilet at work and other occupational environments (eg, an unclean and uncomfortable workplace, dangerous job and probability of accidents, feeling pressed for time and awkward position for long periods). The findings of this review may raise awareness regarding the risk of LUTS among female workers with these factors. From an occupational health perspective, the implementation of tailored prevention strategies based on these occupational factors may prevent female workers from developing LUTS.PROSPERO registration numberCRD42022316728.
Postharvest handling and vase life of cut sunflower
Authors: Kalinowski Jennifer , Moody Erin P. , Dole John M. 
Published: February 2023

The sunflower ( Helianthus annuus L.) is a commercially important cut flower requiring research into postharvest factors such as recutting, water uptake, stem number, cooling rate, and storage temperature to maximize vase life. Stems of 'Sunbright' sunflowers were either recut before or after a drying period up to 48 h. Water uptake, stem quality, and microbial counts were determined 4 days after rehydration. Water potential was determined on five corresponding leaves per treatment. The effects of stem number per vase were evaluated with either 1, 3, 5, or 10 stems. Effects of cooling rate were determined by temperatures of 5 °C for 3 days in the dark, 5 °C for 2 days in the dark preceded by 24 h at either 20 °C with light or 32 °C in a shaded area outdoors, or were maintained in a shaded area at 32 °C for 3 days. Hydration and storage temperature effects were determined by either transferring to a postharvest environment, 20 °C cooler for 2 h, immediate storage for 2 days at 5 °C, or 3 days at 5 °C after recutting the basal stem. Allowing stems to dry up to 48 h reduced vase life by 2.3 days or less. Vase life was unaffected by harvesting into water or by the number of stems in a vase but was affected by temperature such that the longest vase life of 13.2 days occurred when stems were stored for 3 days at 5 ± 0.5 °C followed by postharvest evaluation at 20 ± 1 °C.
Neutron capture cross section of $$^{83}$$Kr
Authors: Fiebiger Stefan , Baramsai Bayarbadrakh , Couture Aaron , Krtička Milan , Mosby Shea , O’Donnell John , Reifarth René , Rusev Gencho , Ullmann John , Weigand Mario , Wolf Clemens 
Published: February 2023

AbstractThe neutron capture cross section of $$^{83}$$

83

Kr has been measured via the time-of-flight technique between 25 meV and 500 keV. The experiment used the DANCE array at the Los Alamos National Laboratory. Maxwellian Averaged Cross Sections have been derived for a range of stellar temperatures and are found to be in good agreement with previous data. The impact of the new cross sections on stellar nucleosynthesis has been investigated.
Accelerator techniques and nuclear data needs for ion beam analysis of wall materials in controlled fusion devices
Authors: Rubel Marek , Primetzhofer Daniel , Petersson Per , Charisopoulos Sotirios , Widdowson Anna 
Published: February 2023

AbstractA brief overview of ion beam analysis methods and procedures in studies of materials exposed to fusion plasmas in controlled fusion devices with magnetic confinement is presented. The role of accelerator techniques in the examination and testing of materials for fusion applications is emphasised. Quantitative results are based on robust nuclear data sets, i.e. stopping powers and reaction cross-sections. Therefore, the work has three major strands: (i) assessment of fuel inventory and modification of wall materials by erosion and deposition processes; (ii) equipment development to perform cutting-edge research; (iii) determination of nuclear data for selected ion-target combinations. Advantages and limitations of methods are addressed. A note is also given on research facilities with capabilities of handling radioactive and beryllium-contaminated materials.
Vortex Structure of Head Bubble in Convective Cloud Starting Plume
Authors: Pinsky Mark , Eytan Eshkol , Gavze Ehud , Khain Alexander 
Published: February 2023

Abstract
A developing cumulus cloud (Cu) was modeled, and dynamic, thermodynamic, and microphysical properties of an ascending head bubble reproducing the upper part of a developing Cu were investigated. The data for analysis are taken from 10-m-resolution LES of trade wind Cu under BOMEX conditions. The detection of a rising bubble is carried out using wavelet filtering of the velocity fields and microphysical fields, while a low-frequency signal of the filtering is associated with the convective-scale structure of cloud. We substantiate and discuss the representation of the bubble as a vortex ring, and estimate the parameters of this vortex ring. The simplest Hill’s vortex was chosen as a model of a vortex ring inside cloud. Analytical approximations of the radial profiles of the vertical velocity and of conservative quantities (such as total water mixing ratio and liquid water potential temperature inside and outside the bubble) are obtained. The spatial structure of these quantities is investigated using analytical expressions. Analytical models for spatial distributions of liquid water content (LWC) and adiabatic fraction (AF) are also designed and analyzed. The results demonstrate the existence of a cloud core with high values of LWC and AF up to the height of 1800 m. The horizontally averaged value of the adiabatic fraction, calculated analytically using the Hill’s vortex concept, is evaluated as 0.39, which is the typical AF value in the upper parts of such Cu. The vertical profiles of different important quantities characterizing cloud structure are presented. The analysis performed in this study allows us to conclude that a rising vortex ring plays the dominating role in formation of the thermodynamic and microphysical structure of developing Cu.

Significance Statement
1) Dynamic and thermodynamic fields of a developing cumulus cloud simulated by high-resolution LES with spectral bin microphysics are separated into convective and turbulent components by means of the wavelet technique. 2) The analysis of convective component of the cloud revealed the existence of a vortex ring at the developing stage of the cloud and evaluate its parameters. 3) The analysis performed in this study allows us to conclude that a rising vortex ring plays the important role in formation of the thermodynamic and microphysical structure of developing Cu. 4) The study provides a novel insight into the cloud–environment interaction. 5) The approximating equations describing the vortex ring can be usefully applied for developing new schemes of convective parameterization.
Relationship between the East Asian Summer and Winter Monsoons at Obliquity Time Scales
Authors: Yan Mi , Liu Zhengyu , Han Jing , Zeng Cheng , Ning Liang , Liu Jian 
Published: February 2023

Abstract
The relationship between the East Asian summer monsoon (EASM) and East Asian winter monsoon (EAWM) across time scales has been an interesting topic for decades. In this study, we quantitatively investigate the EASM–EAWM relationship at the obliquity time scales using a set of accelerated transient simulations. By comparing different indices defined with different variables, we find that the EASM and EAWM intensities are positively correlated under obliquity forcing. High obliquity leads to warmer summertime and cooler wintertime surface temperatures, with a stronger response observed over land than over the oceans. The warmer summertime and cooler wintertime temperature responses are accompanied by a strengthened Asian low in summer and Siberian high in winter, with enhanced southerlies in summer and northerlies in winter, indicating an enhanced EASM and EAWM. Modulated by ice sheet forcing, however, the evolution of the simulated EAWM shifts toward the ice sheet maximum, such that the circulation-based EASM–EAWM relationship in the realistically forced simulation exhibits a phase shift of approximately 11 kyr, closer to the phase between the composite δ18O and loess grain size in observations. Our results may have implications for better understanding the distinct changes in the proxy-based EASM–EAWM relationship before and after the rapid growth of global ice volume at around 3 Ma.

Significance Statement
Studying the relationship between the EASM and EAWM can help us understand the characteristics and mechanisms of the regional climate in response to external forcings at different time scales. By investigating the EASM–EAWM relationship over the past 300 000 years, we find that, forced by obliquity variations, the EASM and EAWM are positively correlated at the obliquity time scales. The ice sheet forcing, meanwhile, also influences the circulation over East Asia and modulates the evolutionary phases between the EASM and EAWM. Our results highlight the importance of the combined impacts of orbital parameters and ice sheets on past climate changes over Asia.
Energy and Momentum of a Density-Driven Overflow in the Samoan Passage
Authors: Voet Gunnar , Alford Matthew H. , Cusack Jesse M. , Pratt Larry J. , Girton James B. , Carter Glenn S. , Klymak Jody M. , Tan Shuwen , Thurnherr Andreas M. 
Published: February 2023

Abstract
The energy and momentum balance of an abyssal overflow across a major sill in the Samoan Passage is estimated from two highly resolved towed sections, set 16 months apart, and results from a two-dimensional numerical simulation. Driven by the density anomaly across the sill, the flow is relatively steady. The system gains energy from divergence of horizontal pressure work
and flux of available potential energy
. Approximately half of these gains are transferred into kinetic energy while the other half is lost to turbulent dissipation, bottom drag, and divergence in vertical pressure work. Small-scale internal waves emanating downstream of the sill within the overflow layer radiate
upward but dissipate most of their energy within the dense overflow layer and at its upper interface. The strongly sheared and highly stratified upper interface acts as a critical layer inhibiting any appreciable upward radiation of energy via topographically generated lee waves. Form drag of
, estimated from the pressure drop across the sill, is consistent with energy lost to dissipation and internal wave fluxes. The topographic drag removes momentum from the mean flow, slowing it down and feeding a countercurrent aloft. The processes discussed in this study combine to convert about one-third of the energy released from the cross-sill density difference into turbulent mixing within the overflow and at its upper interface. The observed and modeled vertical momentum flux divergence sustains gradients in shear and stratification, thereby maintaining an efficient route for abyssal water mass transformation downstream of this Samoan Passage sill.