bluuebunny/crossref_metadata_2025_split huggingface dataset:
Journal of Neurochemistry embraces Transparent Peer Review
Authors: Lawrence Andrew J. , Prado Marco A. M. 
Published: March 2023

AbstractIn this editorial we explain how the Journal of Neurochemistry will embrace Transparent Peer Review. Our goal is to enhance the experience for authors, readers, reviewers, and handling editors and to provide a sound platform for neurochemistry publications. This development is part of our ongoing drive to maintain and further increase the value of the Journal of Neurochemistry for the scientific community.
Disruptive accountability? Temporal regimes and social change in decolonization struggles in Belgium
Authors: DESTROOPER TINE 
Published: March 2023

AbstractTo address the legacies of colonialism, several former colonial states have implemented a range of initiatives commonly considered to belong to the domain of transitional justice (TJ). These contexts are, however, very different from those for which TJ was initially conceptualized. As such, the implementation of elements from the TJ toolbox in these decolonization struggles raises several questions, which this article seeks to address. One of these questions relates to how diverging temporalities affect central normative objectives of TJ, such as accountability. The Belgian case is used to explore how a more pertinent approach to transitional temporalities enables a ‘thicker’ understanding of accountability that re‐centres the debate around accountability's normative objectives in ways that are aligned with the objectives of decolonization struggles. I call this encompassing approach to accountability ‘disruptive accountability’ to underline the normative objective of disrupting harmful social structures and relations.
Employing Genealogies Responsibly in Theology: A Proposal
Authors: Aspray Silvianne 
Published: March 2023

AbstractGenealogical writing has become influential in theology in the past decades. This article critically evaluates the use of the genre of ‘genealogy’ in theology, suggesting that theologians should employ genealogies in (1) an involved and (2) conjectural way. It argues that it generally benefits any genealogy to be involved and conjectural, before showing why there are genuinely theological reasons for taking such stances, making this approach particularly fitting for theologians who wish to employ genealogies.
Does passion matter for team innovation? The conditional indirect effects of team harmonious versus obsessive passion via team reflexivity
Authors: Wei Xin , Liao Hui , Zhang Zhi‐Xue , Dong Yuntao , Li Ning 
Published: March 2023

AbstractThis research examines how team members’ passion for innovation compiles to contribute to team innovation. We argue that team mean passion influences team innovation by affecting team reflexivity, which is a key team process for members to collectively reflect on and adjust their efforts toward achieving innovation goals. The indirect effect of mean passion on team innovation via team reflexivity depends on the nature of passion—harmonious passion (HP) versus obsessive passion (OP)—and the diversity of the corresponding type of passion. Results from a two‐wave field study of 131 teams and a three‐wave field study of 155 teams support the differential effects of compiled HP and OP. Moreover, the effect of mean HP on team reflexivity and its indirect effect on team innovation via reflexivity were less positive when HP diversity was higher rather than lower, while the effect of mean OP on team reflexivity and its indirect effect on team innovation via reflexivity were less negative when OP diversity was higher rather than lower. This research offers important theoretical and practical implications for literatures on passion, teams, and team innovation.
Application of the ecobiodevelopmental model for research among youth experiencing homelessness
Authors: Fitzpatrick Margaret , Ford Jodi L. , Slesnick Natasha 
Published: March 2023

AbstractYouth experiencing homelessness (YEH) often face increased levels of adversity and higher rates of trauma, suicide, and mortality compared to their housed peers. A multi‐level life course lens is proposed by applying the ecobiodevelopmental model to examine social support mechanisms as a buffer to psychopathologies following adversity within YEH. Further discussion contributes to the theoretical basis for future public health research and intervention work addressing youth homelessness and related adversities.
Oral hygiene status in individuals with hearing difficulties: A systematic review and meta‐analysis
Authors: Bhadauria Upendra Singh , Purohit Bharathi , Agarwal Deepali , Priya Harsh , Upadhyay Ashish 
Published: March 2023

AbstractObjectivesMost studies focusing on oral hygiene status in hearing impaired individuals are cross‐sectional and focus on specific populations. A comprehensive literature search and evidence‐based analysis was carried out to assess the oral hygiene status in this special group of population.MethodsSearches were conducted in four databases with no restriction on publication date. Cross‐sectional and comparative cross‐sectional studies assessing the oral hygiene status and periodontal status of hearing impaired individuals using standardized evaluation criteria were included. Study selection, data extraction, and assessment of bias were carried out by four reviewers and oral hygiene, plaque, and gingival status were assessed. The risk of bias assessment was carried out by New Castle Ottawa Quality Assessment Scale. 29 relevant publications that fulfilled the eligibility criteria were included in the systematic review whereas six studies each assessing oral hygiene and plaque status and five studies evaluating the gingival status were included in the Meta‐analysis.ResultsEight thousand eight hundred and ninety (8890) potentially relevant references were identified in the systematic literature search. The overall analysis of the included studies revealed a mean oral hygiene index score of 1.60 (95% CI 0.91‐2.30), Gingival Index scores 1.27 (95% CI 1.02–1.51), and Plaque Index score 0.99 (95% CI 0.75–2.30) among the hearing impaired individuals.ConclusionThe present study reported fair oral hygiene, fair plaque status, and moderate gingivitis among the hearing impaired individuals.
Information theory and machine learning illuminate large‐scale metabolomic responses of Brachypodium distachyon to environmental change
Authors: Mahood Elizabeth H. , Bennett Alexandra A. , Komatsu Karyn , Kruse Lars H. , Lau Vincent , Rahmati Ishka Maryam , Jiang Yulin , Bravo Armando , Louie Katherine , Bowen Benjamin P. , Harrison Maria J. , Provart Nicholas J. , Vatamaniuk Olena K. , Moghe Gaurav D. 
Published: March 2023

SUMMARYPlant responses to environmental change are mediated via changes in cellular metabolomes. However, <5% of signals obtained from liquid chromatography tandem mass spectrometry (LC‐MS/MS) can be identified, limiting our understanding of how metabolomes change under biotic/abiotic stress. To address this challenge, we performed untargeted LC‐MS/MS of leaves, roots, and other organs of Brachypodium distachyon (Poaceae) under 17 organ–condition combinations, including copper deficiency, heat stress, low phosphate, and arbuscular mycorrhizal symbiosis. We found that both leaf and root metabolomes were significantly affected by the growth medium. Leaf metabolomes were more diverse than root metabolomes, but the latter were more specialized and more responsive to environmental change. We found that 1 week of copper deficiency shielded the root, but not the leaf metabolome, from perturbation due to heat stress. Machine learning (ML)‐based analysis annotated approximately 81% of the fragmented peaks versus approximately 6% using spectral matches alone. We performed one of the most extensive validations of ML‐based peak annotations in plants using thousands of authentic standards, and analyzed approximately 37% of the annotated peaks based on these assessments. Analyzing responsiveness of each predicted metabolite class to environmental change revealed significant perturbations of glycerophospholipids, sphingolipids, and flavonoids. Co‐accumulation analysis further identified condition‐specific biomarkers. To make these results accessible, we developed a visualization platform on the Bio‐Analytic Resource for Plant Biology website (https://bar.utoronto.ca/efp_brachypodium_metabolites/cgi‐bin/efpWeb.cgi), where perturbed metabolite classes can be readily visualized. Overall, our study illustrates how emerging chemoinformatic methods can be applied to reveal novel insights into the dynamic plant metabolome and stress adaptation.
Conjugate-Based Numerical Analysis of Parabolic Trough Receiver Pipe With Temperature-Dependent Thermo-Physical Properties of Heat Transfer Fluid Under Laminar Flow Regime
Authors: Anand Sumeet , Kumar Sumit 
Published: March 2023

AbstractIn this article, the use of gas as a working fluid in the parabolic trough receiver (PTR) has been investigated numerically. The present study aims to determine which gas will work best as a heat transfer fluid (HTF) by analyzing the impact of several gases on the PTR’s performance. So, gases, such as carbon dioxide, helium, nitrogen, oxygen, hydrogen, methane, neon, and air, are considered in the present study, which flow through a thick-wall stainless steel pipe under a laminar flow regime. The temperature-dependent thermo-physical properties of the gas are considered. The finite difference method (FDM) with the harmonic mean technique is employed to solve this conjugate heat transfer problem. The current research findings are verified with those reported in the literature and are in excellent agreement. The grid-independent study is conducted to choose the optimal grid size. After that, the multi-objective function optimization technique and performance enhancement factor (PEF) is used to select the best suitable HTF, and it found that hydrogen gas is most appropriate based on these two criteria. Then, the influence of various parametric studies such as Reynolds number, solar flux, and receiver pipe thickness on the Nusselt number has been carried out. It is found that the Nusselt number increases with the Reynolds number while it decreases with solar flux and receiver pipe thickness. The significance of the current study may aid in choosing the appropriate gas as HTF in the parabolic trough solar collector (PTSC).
Geographically skewed recruitment and COVID-19 seroprevalence estimates: a cross-sectional serosurveillance study and mathematical modelling analysis
Authors: Brown Tyler , de Salazar Munoz Pablo Martinez , Bhatia Abhishek , Bunda Bridget , Williams Ellen K , Bor David , Miller James S , Mohareb Amir , Thierauf Julia , Yang Wenxin , Villalba Julian , Naranbai Vivek , Garcia Beltran Wilfredo , Miller Tyler E , Kress Doug , Stelljes Kristen , Johnson Keith , Larremore Dan , Lennerz Jochen , Iafrate A John , Balsari Satchit , Buckee Caroline , Grad Yonatan 
Published: March 2023

ObjectivesConvenience sampling is an imperfect but important tool for seroprevalence studies. For COVID-19, local geographic variation in cases or vaccination can confound studies that rely on the geographically skewed recruitment inherent to convenience sampling. The objectives of this study were: (1) quantifying how geographically skewed recruitment influences SARS-CoV-2 seroprevalence estimates obtained via convenience sampling and (2) developing new methods that employ Global Positioning System (GPS)-derived foot traffic data to measure and minimise bias and uncertainty due to geographically skewed recruitment.DesignWe used data from a local convenience-sampled seroprevalence study to map the geographic distribution of study participants’ reported home locations and compared this to the geographic distribution of reported COVID-19 cases across the study catchment area. Using a numerical simulation, we quantified bias and uncertainty in SARS-CoV-2 seroprevalence estimates obtained using different geographically skewed recruitment scenarios. We employed GPS-derived foot traffic data to estimate the geographic distribution of participants for different recruitment locations and used this data to identify recruitment locations that minimise bias and uncertainty in resulting seroprevalence estimates.ResultsThe geographic distribution of participants in convenience-sampled seroprevalence surveys can be strongly skewed towards individuals living near the study recruitment location. Uncertainty in seroprevalence estimates increased when neighbourhoods with higher disease burden or larger populations were undersampled. Failure to account for undersampling or oversampling across neighbourhoods also resulted in biased seroprevalence estimates. GPS-derived foot traffic data correlated with the geographic distribution of serosurveillance study participants.ConclusionsLocal geographic variation in seropositivity is an important concern in SARS-CoV-2 serosurveillance studies that rely on geographically skewed recruitment strategies. Using GPS-derived foot traffic data to select recruitment sites and recording participants’ home locations can improve study design and interpretation.
Changes in mortality among patients with chronic obstructive pulmonary disease from the 1990s to the 2000s: a pooled analysis of two prospective cohort studies
Authors: Sato Susumu , Oga Toru , Muro Shigeo , Tanimura Kazuya , Tanabe Naoya , Nishimura Koichi , Hirai Toyohiro 
Published: March 2023

ObjectivesThis study aimed to identify and investigate changes in the mortality of patients with chronic obstructive pulmonary disease (COPD) at the same institute from the 1990s to the 2000s. We hypothesised that the improvement in long-term mortality of COPD was achieved due to the development of pharmacological and non-pharmacological treatments.DesignThis study was a retrospective analysis of two observational prospective cohort studies. One study enrolled subjects from 1995 to 1997 (the 1990s), and the other enrolled subjects from 2005 to 2009 (the 2000s).SettingTwo studies from a single centre, which was the same university hospital in Japan.ParticipantsPatients with stable COPD.Primary and secondary outcome measuresWe analysed all-cause mortality data from the pooled database. Subanalyses were conducted by stratifying subjects into two groups according to airflow limitation severity as severe/very severe (per cent predicted value of forced expiratory volume in 1 s (%FEV1) <50%) or mild/moderate (%FEV1≥50%).ResultsIn total, 280 male patients with COPD were enrolled. Patients in the 2000s (n=130) were significantly older (71.6 vs 68.7 years) and had milder disease (%FEV1; 57.6% vs 47.1%) than those in the 1990s (n=150). Almost all severe/very severe patients in the 2000s received long-acting bronchodilators (LABDs), and they had a significantly lower risk of mortality than those in the 1990s according to Cox proportional regression analyses (OR=0.34, 95% CI 0.13–0.78), with a 48% reduction in 5-year mortality (from 31.0% to 16.1%). Moreover, any LABD use had a significantly positive impact on prognosis, even after adjustments for age, FEV1, smoking status, dyspnoea, body size, oxygen therapy and study period.ConclusionsTrends indicating a better prognosis for patients with COPD in the 2000s were observed. This improvement may be associated with the usage of LABDs.
Effectiveness of spiritual interventions on psychological outcomes and quality of life among paediatric patients with cancer: a study protocol for a systematic review
Authors: Liu Qi , Ho Ka Yan , Lam Katherine Ka Wai , Ho Jacqueline Mei Chi , Lam Winsome , Ma Polly , Abu-Odah Hammoda , Belay Getaneh Mulualem , Ling Dong-Lan , Ching Shirley-Siu-Yin , Wong Frances-Kam-Yuet 
Published: March 2023

IntroductionCancer and its treatment affect children’s physical, psychological and social well-being throughout the disease trajectory. Spiritual well-being is a fundamental dimension of people’s overall health and is considered a source of strength to motivate patients to cope with and adapt to their disease. Appropriate spiritual interventions are important to mitigate the psychological impact of cancer on children, with an ultimate goal of improving their quality of life (QoL) throughout the treatment course. However, the overall effectiveness of spiritual interventions for paediatric patients with cancer remains unclear. This paper describes a protocol to systematically summarise the characteristics of studies related to existing spiritual interventions and synthesise their effectiveness on psychological outcomes and QoL among children with cancer.Methods and analysisTen databases will be searched to identify appropriate literature: MEDLINE, the Cochrane Central Register of Controlled Trials, EMBASE, CINAHL, PsycINFO, LILACS, OpenSIGLE, the Chinese Biomedical Literature Database, the Chinese Medical Current Contents and the Chinese National Knowledge Infrastructure. All randomised controlled trials that meet our inclusion criteria will be included. The primary outcome will be QoL as evaluated by self-reported measures. The secondary outcomes will be self-reported or objectively measured psychological outcomes, including anxiety and depression. Review Manager V.5.3 will be used to synthesise the data, calculate treatment effects, perform any subgroup analyses and assess the risk of bias in included studies.Ethical and disseminationThe results will be presented at international conferences and published in peer-reviewed journals. As no individual data will be involved in this review, ethical approval is not required.
EffectiveNess of a multimodal preHAbilitation program in patieNts with bladder canCEr undergoing radical cystectomy: protocol of the ENHANCE multicentre randomised controlled trial
Authors: Akdemir Emine , Sweegers Maike G , Vrieling Alina , Rundqvist Helene , Meijer Richard P , Leliveld-Kors Annemarie M , van der Heijden Antoine G , Rutten Vera C , Koldewijn Evert L , Bos Siebe D , Wijburg Carl J , Marcelissen Tom A T , Bongers Bart C , Retèl Valesca P , van Harten Wim H , May Anne M , Groen Wim G , Stuiver Martijn M 
Published: March 2023

IntroductionRadical cystectomy (RC) is the standard treatment for patients with non-metastatic muscle-invasive bladder cancer, as well as for patients with therapy refractory high-risk non-muscle invasive bladder cancer. However, 50–65% of patients undergoing RC experience perioperative complications. The risk, severity and impact of these complications is associated with a patient’s preoperative cardiorespiratory fitness, nutritional and smoking status and presence of anxiety and depression. There is emerging evidence supporting multimodal prehabilitation as a strategy to reduce the risk of complications and improve functional recovery after major cancer surgery. However, for bladder cancer the evidence is still limited. The aim of this study is to investigate the superiority of a multimodal prehabilitation programme versus standard-of-care in terms of reducing perioperative complications in patients with bladder cancer undergoing RC.Methods and analysisThis multicentre, open label, prospective, randomised controlled trial, will include 154 patients with bladder cancer undergoing RC. Patients are recruited from eight hospitals in The Netherlands and will be randomly (1:1) allocated to the intervention group receiving a structured multimodal prehabilitation programme of approximately 3–6 weeks, or to the control group receiving standard-of-care. The primary outcome is the proportion of patients who develop one or more grade ≥2 complications (according to the Clavien-Dindo classification) within 90 days of surgery. Secondary outcomes include cardiorespiratory fitness, length of hospital stay, health-related quality of life, tumour tissue biomarkers of hypoxia, immune cell infiltration and cost-effectiveness. Data collection will take place at baseline, before surgery and 4 and 12 weeks after surgery.Ethics and disseminationEthical approval for this study was granted by the Medical Ethics Committee NedMec (Amsterdam, The Netherlands) under reference number 22–595/NL78792.031.22. Results of the study will be published in international peer-reviewed journals.Trial registration numberNCT05480735.
Interest in advance provision of abortion pills: a national survey of potential users in the USA
Authors: Lerma Klaira , Blumenthal Paul D 
Published: March 2023

ObjectiveTo assess interest in clinician-administered advance provision of abortion pills among potential users in the USA.MethodsUsing social media advertisements, we recruited people living in the USA who were aged 18–45 years and assigned female at birth, who were not pregnant or planning pregnancy, for an online survey on reproductive health experiences and attitudes. We explored interest in advance provision of abortion pills, participant characteristics, including demographics and pregnancy history, contraceptive use, abortion knowledge and comfort, and healthcare system distrust. We used descriptive statistics to assess interest in advance provision, and ordinal regression modelling to evaluate differences in interest controlling for age, pregnancy history, contraceptive use, familiarity and comfort with medication abortion, and healthcare system distrust, reporting adjusted odds ratios (aORs) and 95% confidence intervals (95% CIs).ResultsFrom January-February 2022, we recruited 634 diverse respondents from 48 states, among whom 65% were interested, 12% neutral, and 23% disinterested in advance provision. There were no differences among interest groups by US region, race/ethnicity, or income. In the model, variables associated with interest included being aged 18–24 years (aOR 1.9, 95% CI 1.0 to 3.4) versus 35–45 years, using a tier 1 (permanent or long-acting reversible) or tier 2 (short-acting hormonal) contraceptive method (aOR 2.3, 95% CI 1.2 to 4.1, and aOR 2.2, 95% CI 1.2 to 3.9, respectively) versus no contraception, being familiar or comfortable with the medication abortion process (aOR 4.2, 95% CI 2.8 to 6.2, and aOR 17.1, 95% CI 10.0 to 29.0, respectively), and having high healthcare system distrust (aOR 2.2, 95% CI 1.0 to 4.4) versus low distrust.ConclusionAs abortion access becomes more constrained, strategies are needed to ensure timely access. Advance provision is of interest to the majority of those surveyed and warrants further policy and logistical exploration.