bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE EFFECTIVENESS OF USING REACTIVE PROGRAMMING FOR FINTECH WEB APPLICATION MODULES
Authors: Болдарев Максим Андреевич 
Published: January 2025

Статья посвящена анализу применения реактивной парадигмы в разработке финансовых веб-приложений с использованием Spring Web Flux. Рассматриваются ключевые принципы реактивного программирования, включая асинхронные API, управление потоками данных и механизм обратного давления, который позволяет оптимизировать взаимодействие между источниками и потребителями данных. Подчеркивается, что реактивные архитектуры обеспечивают высокую производительность и низкую задержку при обработке больших объемов транзакционных данных, что особенно актуально в условиях динамичного финансового рынка. Автор акцентирует внимание на преимуществах реактивного подхода, таких как возможность обработки асинхронных событий в реальном времени, снижение вычислительных затрат и улучшение пользовательского опыта. Статья также описывает, как внедрение реактивных систем может привести к повышению удовлетворенности пользователей и снижению оттока клиентов. В заключение подчеркивается, что переход к реактивным архитектурам открывает новые возможности для повышения эффективности и конкурентоспособности финансовых приложений
The article focuses on the analysis of the application of the reactive paradigm in the development of financial web applications using Spring Web Flux. Key principles of reactive programming are discussed, including asynchronous APIs, data flow management, and the backpressure mechanism that optimizes interaction between data sources and consumers. It is emphasized that reactive architectures provide high performance and low latency in processing large volumes of transactional data, which is particularly relevant in the context of a dynamic financial market. The author highlights the advantages of the reactive approach, such as the ability to handle asynchronous events in real-time, reduced computational costs, and improved user experience. The article also describes how the implementation of reactive systems can lead to increased user satisfaction and decreased customer churn. In conclusion, it is emphasized that transitioning to reactive architectures opens up new opportunities for enhancing efficiency and competitiveness in financial applications
STRESS AS A PSYCHOPHYSIOLOGICAL PHENOMENON, ITS FEATURES AND CAUSES
Authors: Эйваззаде Айнур Сулейман кызы 
Published: January 2025

Сходство стресса и дистресса заключается в том, что все эти состояния психики человека в большей или меньшей степени пагубно влияют на здоровье, разрушают его, нарушают равновесие, препятствуют заключаются в том, что стресс, например, в отличие от дистресса, несет в себе только негативное последствие для организма в целом и психики в частности, но положительные переживания, сопровождающиеся выработкой «хорошего» адреналина, радость), а это в свою очередь дает человеку положительный заряд, но даже «хороший» стресс, чрезмерно сильные эмоции могут привести к крушению сна, расстроить равновесие и помешать концентрации внимания. Стрессу подвержены все, это не только зло, не только беда, но и великое благо, ведь разного рода стрессов наша жизнь выглядела бы каким-то бесцветным. Активность - единственный способ избавиться от стресса. Сосредоточенность на светлых сторонах жизни и на действиях, способных менять ситуацию, не только сохраняет здоровье, но и способствует успеху
The similarity of stress and distress lies in the fact that all this state of the human psyche is more or less detrimental to health, destroy it, upset the balance, hinder high efficiency, the ability to think sensibly and objectively assess the reality around you. The differences lie in the fact that stress, for example, unlike distress, carries not only a negative consequence for the body as a whole and the psyche in particular, but also positive experiences accompanied by the production of “good” adrenaline (love, joy), and this in turn gives a person a positive charge, but it is worth dosing is even “good” stress, excessively strong emotions can lead to sleep disturbances, upset balance and interfere with concentration
THEORY AND PRACTICE OF STRATEGY AS AN OBJECT OF INNOVATION: FROM THE EXPERIENCE OF THE WORK OF THE STATE EDUCATIONAL INSTITUTION GYMNASIUM №622 OF THE VYBORG DISTRICT OF ST. PETERSBURG
Authors: Корнева Юлия Владимировна , Соколова Людмила Алексеевна 
Published: January 2025

В статье рассматривается эффективность теории и практики стратегирования как объекта инновационной деятельности; обучение методам стратегирования способствует формированию у учащихся актуальных компетенций для более глубокого понимания современной ситуации, развивается гибкость мышления для решения глобальных задач, связанных с благополучием будущего страны
The article examines the effectiveness of the theory and practice of strategizing as an object of innovative activity; teaching strategizing methods contributes to the formation of relevant competencies among students for a deeper understanding of the current situation, develops flexibility of thinking to solve global problems related to the well-being of the country's future
A hospitalização e a infância: relato de ação lúdica prévia a procedimento invasivo
Authors: Moda Catharina , Petroucic Roberta Thomé 
Published: January 2025

Introdução: O direito de brincar, fundamental na infância, mostra-se fragilizado durante a internação hospitalar. A humanização em saúde envolve a ludicidade na oncologia infantil. Relato de experiência: por meio do Grupo Acadêmico de Atividades Lúdicas, estudantes de medicina capacitados realizaram inserções no Hospital de Amor infantil, promovendo atividades lúdicas, como trocas simbólicas de papéis e uso de brinquedo terapêutico instrucional. Isto levou a amenização do ambiente nas situações prévias a procedimentos invasivos e maior conhecimentos sobre os mesmos, por parte dos pacientes infantis. Discussão: conforme relatado, a literatura aponta os benefícios do brincar e o uso de brinquedos terapêuticos instrucionais como importantes meios de proporcionar maior autonomia e bem-estar da criança, bem como de contribuir para seu tratamento de saúde. Considerações finais: Ferramentas lúdicas permitiram o ensino sobre procedimentos de rotina hospitalar e propiciaram o direito de brincar. Estudantes de medicina tiveram a oportunidade de crescimento pessoal e ampliação da visão acerca de todo o contexto biopsicossocial que envolve a hospitalização infantil.
Comparative Analysis of Growth Media for Cultivating Acanthamoeba: Implications for Laboratory Diagnostics
Authors: Dalimi Abdolhossein , Mohammady Ali Reza 
Published: January 2025

Background Acanthamoeba, a genus of free-living amoebae found in soil, freshwater, and marine habitats, is crucial in environmental studies and medical microbiology due to its potential to cause severe human infections. Cultivating Acanthamoeba is crucial for diagnosing infections, guiding treatment, and assessing exposure risks to pathogenic strains. This study aims to compare different culture media for cultivating Acanthamoeba under laboratory conditions.
Materials and Methods The study examined ten culture media for Acanthamoeba growth, including TSB, Trypticase soy agar (TSA), Trypticase soy yeast (TSY), Trypticase yeast iron-extracted (TYI), Trypticase, yeast maltose extract (TYM), Pepton Yeast Glucose Extract (PYG), Dulbecco's modified Eagle's medium (DMEM), RPMI 1640, Serum Casein Glucose Yeast Extract (SCGY), Coconut powder suspension in NNA medium, as well as non-nutrient agar (NNA) as the primary & control culture.
Results The results showed varied growth rates of Acanthamoeba when cultured in different media, highlighting important trends in their adaptability and growth based on the nutritional composition of the media provided. In TSB, TSA, DMEM/F12 and SCGY media, no growth was observed, suggesting that the combination may lack essential nutrients or conditions necessary for fostering Acanthamoeba proliferation. TYI showed an excellent growth rate for Acanthamoeba, particularly notable during the first 24-72 hours. The use of maltose as a carbon source and FBS in the NNA environment appears to promote rapid proliferation of Acanthamoeba. Coconut powder suspension in NNA medium led to excellent growth rates of Acanthamoeba.
Conclusion The effective cultivation of Acanthamoeba in TYI, TYM, and coconut powder highlights the significance of refining nutrient composition to enhance culturing methods.
Economía de la Provincia de Herrera y los créditos de la banca privada. Años: 2018-2022
Authors: Tuñon G Edwin A 
Published: January 2025

La economía de la provincia de Herrera, es una economía pequeña, dinámica en la entrada de la península de Azuero. El objetivo del artículo es caracterizar la actividad principal y los sectores de la economía. Se ha pasado de crecer sola, a una economía con una actividad de no mercado como principal. Métodos y Materiales. El desarrollo del artículo se utilizan los informes institucionales del Ministerio de Economía y Finanzas, sobre el comportamiento de la economía panameña. De la estadística de cuentas nacionales provinciales, los datos correspondientes a la economía herrerana, se clasificaron los tres sectores de la economía; primario, secundario y terciario. Se promedió el aporte porcentual de cada una de las actividades económicas, para identificar el principal sector y la actividad económica principal. Discusión: La economía herrerana, presenta una estructura terciaria y en cuanto a actividad; actividades la de no mercado, actividades de la administración pública. La banca privada en la provincia de Herrera prioriza en el periodo los créditos al sector servicios. Conclusiones: La economía de la provincia de Herrera es una economía de servicios o terciaria, cuya principal actividad es otra producción de no mercado, la administración pública el estado, apoyo del estado que evita que se apague. Los créditos prioritarios son al consumo personal(improductivo)
La Economía de la provincia de Los Santos y los créditos bancarios. Años: 2018-2022
Authors: Tuñon G Edwin A 
Published: January 2025

El objetivo del artículo es conocer la economía santeña desde los sectores económicos: primario, secundario, terciario y sus tres principales actividades en el periodo 2018-2022. La economía es dinámica, y la estructura sectorial e importancia de las actividades cambia, hoy hay un vacío de conocimiento acerca de las características y actividades económicas principales en la economía provincial durante periodo 2018-2022. Métodos y Materiales: El desarrollo del artículo revise los informes institucionales del Ministerio de Economía y Finanzas, sobre el comportamiento de la economía panameña. Informaciones de canales YouTube con información de la economía santeña. De la estadística de cuentas nacionales provinciales del Instituto Nacional de Estadística INEC con los datos correspondientes a la economía santeña, se clasificaron los tres sectores de la economía: primario, secundario y terciario. Se promedió el aporte de cada una de las actividades económicas, para identificar entre ellas las principales de esta economía en orden descendente encontrando: Otra producción de no mercado. Agricultura, ganadería, construcción. Discusión: La economía santeña, presenta una estructura terciaria y en cuanto a actividad principal la no mercado o administración pública. Es una economía que la realidad actual desafío realidades que son desbordadas por el modelo de economía actual. Conclusiones: La economía de la provincia de santeña es una economía de servicios o terciaria, cuya principal actividad es la otra producción de no mercado, la agricultura, ganadería y la actividad de la construcción. Economía de servicios de no mercado, producción de alimentos en construcción.
La Falta de Capacitación Docente en Atención a la Diversidad: Un Obstáculo para la Educación Inclusiva en un Mundo Globalizado
Authors: Beltrán Arcos María Teresa , Chalco Sandovalin Mario Rodrigo , Mosquera Vinueza María Gabriela , Melendes Lucero Wilson Gonzalo , Pachacama Tipan Sandra Elizabeth 
Published: January 2025

Objetivo: Realizar un análisis sistemático de la carencia de formación para profesores en necesidades educativas especiales (NEE) en Ecuador, estudiando los elementos que restringen la formación apropiada y sus efectos en la inclusión educativa, con el fin de justificar la urgencia de intervención en este sector." Selección de estudios y datos: Mediante una búsqueda electrónica y manual se identificaron 117 artículos, incluyéndose 20 trabajos de investigación que cumplieron con los criterios de selección. Estrategia de investigación: La investigación se fundamenta en una revisión realizada bajo el modelo PRISMA, que recolectó datos de bases de datos académicas como Scopus, SciELO y Google Académico, incluyendo estudios publicados desde 2018. Síntesis de resultados: Los descubrimientos señalan que, pese a los progresos en la incorporación de temas vinculados a la diversidad en los programas de capacitación para profesores, estos no son suficientes para garantizar prácticas inclusivas eficaces en las clases. Conclusión: Finalmente, se ofrecen sugerencias específicas para potenciar la formación de los profesores, que comprenden programas de formación continua, un acceso ampliado a tecnologías y recursos personalizados, además de un enfoque de colaboración que englobe a la comunidad educativa.
Coconstruire les récits de l’(auto)mobilité : la sociologie visuelle embarquée en convoi
Authors: Brodersen Meike 
Published: January 2025

L’alliance des méthodes mobiles et des méthodes visuelles retrouve une actualité renouvelée dans l’étude des mobilités futures. Impératifs écologiques, politiques publiques et annonces d’innovation technologique questionnent les pratiques (auto)mobiles et rendent nécessaire d’appréhender conjointement les mobilités quotidiennes du présent et les imaginaires de l’avenir, et cela en mouvement. Cet article propose la méthode du convoi audiovisuel et automobile pour réaliser une sociologie située et collaborative des mobilités quotidiennes, qui permet d’offrir des prises heuristiques au-delà même de l’analyse sociologique. Le visuel y devient un site d’interaction qui rend explicites les connaissances tacites et compétences situées liées à la mobilité quotidienne ; il permet de documenter et de rendre présente l’épaisseur relationnelle et expérientielle de l’espace du proche. La coconstruction du récit automobile filmé permet de mettre en évidence les modalités spécifiques des socialités locales en tant qu’elles sont imbriquées dans les pratiques de mobilité, y compris par les difficultés et imperfections qui émergent lors de ces embarquements.
Définir le « feuilleton sociologique »
Authors: Thériault Barbara , Pector-Lallemand Jules 
Published: January 2025

Il y a dix ans, Sociologie et sociétés (vol. 45, no 2, automne 2013) publiait les premiers textes de sa nouvelle rubrique « Feuilleton », une traduction inédite de trois reportages rédigés en 1926 par Joseph Roth. La création de la rubrique s’inscrivait dans le sillage des travaux d’un groupe de recherche de l’Université de Montréal qui se penchait sur les écrits de Siegfried Kracauer (1889-1966), en particulier ses « feuilletons sociologiques » parus dans les journaux de 1925 à 1933. C’est en organisant des séminaires, en menant des enquêtes sur des phénomènes contemporains et en publiant divers articles et ouvrages sur le thème que ce groupe a mis en branle un programme de recherche sur deux axes : le premier proposant des recherches empiriques inspirées de la démarche de Kracauer ; le second visant une investigation historique sur la naissance de la sociologie et ses liens avec le journalisme. En effet, si cette connexion est visible dans le cas de la sociologie américaine (Lindner, 2007 [1990]), elle l’est moins dans celui de la sociologie classique allemande. Ultimement, ces deux axes tendaient vers un but : renouveler l’écriture sociologique à une époque où la discipline peine parfois à joindre de larges publics, dans un contexte d’omniprésence du regard psychologique et neurobiologique. Dans cet article-bilan, les auteurs définissent le « feuilleton sociologique » sous la forme d’une entrée Wikipédia, afin de préciser les contours de ce terme flou.
Second‐order extended state observers‐based adaptive event‐triggered containment control for nonlinear multiagent systems with mismatched stochastic disturbances
Authors: Zuo Chaochao , Cao Liang , Ren Hongru , Xue Hong 
Published: September 2023

SummaryThis article investigates the event‐triggered containment control problem for nonlinear multiagent systems with mismatched stochastic disturbances. A set of second‐order extended state observers (ESOs) is constructed to solve the problem of bounded stochastic disturbances. The observers are able to estimate the disturbances in each control input channel in real‐time and solve the problem of stochastic disturbances path non‐differentiability. Based on backstepping technique, adaptive controllers are designed to ensure that the output of the followers converge to the convex hull formed by the leaders. Moreover, a simplified event‐triggered threshold condition is designed, which effectively reduces the update frequency of the controller and the complexity of threshold condition. Based on the Lyapunov stability theorem, it is proved that all signals in the closed‐loop systems are the practically bounded. Finally, the effectiveness of the proposed control scheme is verified by simulation results.
Mn2+/Ir3+‐Doped and CaCO3‐Covered Prussian Blue Nanoparticles with Indocyanine Green Encapsulation for Tumor Microenvironment Modulation and Image‐Guided Synergistic Cancer Therapy
Authors: Ma Shuaining , Xu Weiguo , Fei Yunwei , Li Dan , Jia Xiuna , Wang Jin , Wang Erkang 
Published: September 2023

AbstractThe development of smart theranostic nanoplatforms has gained great interest in effective cancer treatment against the complex tumor microenvironment (TME), including weak acidity, hypoxia, and glutathione (GSH) overexpression. Herein, a TME‐responsive nanoplatform named PMICApt/ICG, based on PB:Mn&Ir@CaCO3Aptamer/ICG, is designed for the competent synergistic photothermal therapy and photodynamic therapy (PDT) under the guidance of photothermal and magnetic resonance imaging. The nanoplatform's aptamer modification targeting the transferrin receptor and the epithelial cell adhesion molecule on breast cancer cells, and the acid degradable CaCO3 shell allow for effective tumor accumulation and TME‐responsive payload release in situ. The nanoplatform also exhibits excellent PDT properties due to its ability to generate O2 and consume antioxidant GSH in tumors. Additionally, the synergistic therapy is achieved by a single wavelength of near‐infrared laser. RNA sequencing is performed to identify differentially expressed genes, which show that the expressions of proliferation and migration‐associated genes are inhibited, while the apoptosis and immune response gene expressions are upregulated after the synergistic treatments. This multifunctional nanoplatform that responds to the TME to realize the on‐demand payload release and enhance PDT induced by TME modulation holds great promise for clinical applications in tumor therapy.
Monolithic 3D Integration of Analog RRAM‐Based Computing‐in‐Memory and Sensor for Energy‐Efficient Near‐Sensor Computing
Authors: Du Yiwei , Tang Jianshi , Li Yijun , Xi Yue , Li Yuankun , Li Jiaming , Huang Heyi , Qin Qi , Zhang Qingtian , Gao Bin , Deng Ning , Qian He , Wu Huaqiang 
Published: September 2023

AbstractIn the era of the Internet of Things, vast amounts of data generated at sensory nodes impose critical challenges on the data‐transfer bandwidth and energy efficiency of computing hardware. A near‐sensor computing (NSC) architecture places the processing units closer to the sensors such that the generated data can be processed almost in situ with high efficiency. This study demonstrates the monolithic three‐dimensional (M3D) integration of a photosensor array, analog computing‐in‐memory (CIM), and Si complementary metal‐oxide‐semiconductor (CMOS) logic circuits, named M3D‐SAIL. This approach exploits the high‐bandwidth on‐chip data transfer and massively parallel CIM cores to realize an energy‐efficient NSC architecture. The 1st layer of the Si CMOS circuits serves as the control logic and peripheral circuits. The 2nd layer comprises a 1 k‐bit one‐transistor‐one‐resistor (1T1R) array with InGaZnOx field‐effect transistor (IGZO‐FET) and resistive random‐access memory (RRAM) for analog CIM. The 3rd layer comprises multiple IGZO‐FET‐based photosensor arrays for wavelength‐dependent optical sensing. The structural integrity and function of each layer are comprehensively verified. Furthermore, NSC is implemented using the M3D‐SAIL architecture for a typical video keyframe‐extraction task, achieving a high classification accuracy of 96.7% as well as a 31.5× lower energy consumption and 1.91× faster computing speed compared to its 2D counterpart.
A Novel Superparamagnetic Multifunctional Nerve Scaffold: A Remote Actuation Strategy to Boost In Situ Extracellular Vesicles Production for Enhanced Peripheral Nerve Repair
Authors: Xia Bing , Gao Xue , Qian Jiaqi , Li Shengyou , Yu Beibei , Hao Yiming , Wei Bin , Ma Teng , Wu Haining , Yang Shijie , Zheng Yi , Gao Xueli , Guo Lingli , Gao Jianbo , Yang Yujie , Zhang Yongfeng , Wei Yitao , Xue Borui , Jin Yan , Luo Zhuojing , Zhang Jin , Huang Jinghui 
Published: September 2023

AbstractExtracellular vesicles (EVs) have inherent advantages over cell‐based therapies in regenerative medicine because of their cargos of abundant bioactive cues. Several strategies are proposed to tune EVs production in vitro. However, it remains a challenge for manipulation of EVs production in vivo, which poses significant difficulties for EVs‐based therapies that aim to promote tissue regeneration, particularly for long‐term treatment of diseases like peripheral neuropathy. Herein, a superparamagnetic nanocomposite scaffold capable of controlling EVs production on‐demand is constructed by incorporating polyethyleneglycol/polyethyleneimine modified superparamagnetic nanoparticles into a polyacrylamide/hyaluronic acid double‐network hydrogel (Mag‐gel). The Mag‐gel is highly sensitive to a rotating magnetic field (RMF), and can act as mechano‐stimulative platform to exert micro/nanoscale forces on encapsulated Schwann cells (SCs), an essential glial cell in supporting nerve regeneration. By switching the ON/OFF state of the RMF, the Mag‐gel can scale up local production of SCs‐derived EVs (SCs‐EVs) both in vitro and in vivo. Further transcriptome sequencing indicates an enrichment of transcripts favorable in axon growth, angiogenesis, and inflammatory regulation of SCs‐EVs in the Mag‐gel with RMF, which ultimately results in optimized nerve repair in vivo. Overall, this research provides a noninvasive and remotely time‐scheduled method for fine‐tuning EVs‐based therapies to accelerate tissue regeneration, including that of peripheral nerves.
Synthetic Study on the Lycoricidine Alkaloids
Authors: Denis Maxime , Blais Samuel , Canesi Sylvain 
Published: September 2023

AbstractA stereoselective synthesis of isolycoricidine, a natural product belonging to the Amaryllidaceae alkaloids family was produced. In addition, a synthetic study on the main core of lycoricidine led to the formation of analogues and a diastereomer of dihydrolycoricidine. Our strategy was based on an oxidative phenol dearomatization, a stereoselective Heck process, a selective dihydroxylation on a dienone system, several stereoselective reductions, and an oxidative retro‐Michael procedure as an amine‐deprotecting group strategy. Furthermore, two steps highlight the usefulness of hypervalent iodines in total synthesis of natural products.