bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hubungan Ability to Pay dan Willingness to Pay Dengan Kepatuhan Membayar Iuran Program Jaminan Kesehatan Nasional
Authors: Mentari Witri Dewi 
Published: June 2023

Jaminan Kesehatan Nasional (JKN) mulai diberlakukan sejak Januari 2014. Dalam rogram JKN ini, pemerintah menargetkan angka Universal Health Coverage (UHC) sebesar 95% pada 2019. Sampai dengan tahun 2020, cakupan nasional program JKN baru mencapai 85% dan Sumedang menjadi salah satu daerah dengan cakupan terendah. Masalah lainnya adalah rendahnya kepatuhan peserta dalam membayar iuran JKN. Penelitian ini bertujuan untuk mengetahui hubungan antara ATP dan WTP dengan kepatuhan membayar, serta untuk mengetahui faktor mana yang lebih menentukan kepatuhan membayar jaminan kesehatan.Jenis penelitian adalah analitik dengan desain correlational. Populasi penelitian ini adalah peserta mandiri program JKN di Kelurahan Situ yang berjumlah 1551 KK, dengan jumlah sampel 100 yang ditentukan dengan rumus Slovin. Analisis yang digunakan yaitu dengan range spearman, analisis multivariat dengan regresi logistik berganda. Hasil penelitian menunjukkan p-value sebesar 0.000 untuk variabel ATP dan WTP sehingga dibuktikan bahwa ada hubungan antara ATP ataupun WTP dengan kepatuhan membayar. Uji regresi logistik berganda menunjukkan hasil hahwa faktor WTP determinan dengan kepatuhan membayar. Disimpulkan bahwa ada hubungan antara ATP dan WTP dengan kepatuhan peserta mandiri program JKN. WTP determinan dengan kepatuhan membayar.
Kata Kunci : ATP, WTP, Kepatuhan Membayar.
Representasi Pesan Edukasi dalam Iklan di Youtube (Studi Semiotika Roland Barthes pada Iklan Konditioner Pantene)
Authors: Ramdhania Annisa Ramdhania 
Published: June 2023

Alasan mengapa peneliti memilih membahas tentang iklan konditioner Pantene ini karena dalam waktu 24 jam iklan ini telah disaksikan oleh 950,773 penonton dan dinyatakan oleh Senior Brand Manager Pantene Indonesia bahwa penjualan produk meningkat dan membuat produk konditioner ini sempat habis dimana-mana. Penelitian ini merupakan penelitian kualitatif dan deskriptif. Peneliti menggunakan teori Roland Barthes untuk memahami makna dalam iklan pantene dan khalayak yang menonton iklan tersebut untuk ajakan pembelian sebuah produk. Iklan Pantene Hair Miracles Treatmen Conditioner menceritakan mengenai emosi yang tidak terkontrol karena kelelahan, hal ini kemudian mempengaruhi kehidupan sosial karakter Keanu. Namun setelah marah-marah dan mengomel, tidak ditemukan solusi atas emosi tidak terkontrolnya, setelah berdiskusi dengan voice over ditemukan jika bisa jadi sumber dari segala emosi dan marahnya itu adalah rambut yang kecapekan dan membutuhkan perawatan agar bisa terisi kembali dayanya. Visual dan audio yang ditampilkan melalui tabel analisis memperliatkan bahwa sebagai manusia, kita memiliki tanggung jawab dalam mengurus diri sendiri. Visual dan audio yang telah dianalisis menggunakan Semiotik Barthes juga memperlihatkan pentingnya untuk tidak emosi karena emosi hanya akan menambah kekacauan dan tidak menemukan solusi dari suatu permasalahan. Visual dan audio yang telah dianalisis pada tabel hasil penelitian juga memperlihatkan pesan edukasi proses memperbaiki diri.
Method Development and Validation for Quantitative Estimation of Bortezomib in its Bulk and Pharmaceutical Formulation
Authors: Srikanth Banothu , Pavani Badi , Keerthana Ollepu , Hussain Iqbal , Indira H. , Vamshi Adike , Mondal Faruk 
Published: June 2023

A new method was established for estimation of Bortezomib by RP-HPLC method. The chromatographic conditions were successfully developed for the separation of Bortezomib by using Phenomenex Luna C18 column 250x4.6mm 5µm, flow rate was 1.0 ml/min, mobile phase ratio was Acetonitrile : 0.1% formic acid (50: 50 v/v),detection wavelength was 280 nm. The retention time was found to be 5.3 mins. The % purity of Bortezomib was found to be 100.443% respectively. The system suitability parameters for Bortezomib such as theoretical plates and tailing factor were found to be more than 2000 and less than 2 respectively, the resolution was found to be less than 2. The analytical method was validated according to ICH guidelines (ICH, Q2 (R1). The linearity study for Bortezomib was found in concentration range of 20µg-120µg/ml and correlation coefficient (r2) was found to be 0.9994, % recovery was found to be 101.37%, % RSD for repeatability was 1.778, % RSD for intermediate precision was 1.537 respectively. The precision study was precise, robust, and repeatable. LOD value was 2.6402, and LOQ value was 7.281 respectively. Hence the suggested RP-HPLC method can be used for routine analysis of Bortezomib in API and pharmaceutical dosage form.
Keywords: Analytical Validation, Bortezomib, Phamarmaceutical, formulation.
Exploring the Potential of Ketoprofen Nanosuspension: In Vitro and In Vivo Insights into Drug Release and Bioavailability
Authors: Sanas Mahesh N. , Pachpute Tejas S. 
Published: June 2023

Low water solubility and high permeability present formulation challenges for drugs categorized as Biopharmaceutics Classification System (BCS) Class II, resulting in reduced bioavailability. This research focuses on addressing the solubility issues of BCS Class II drugs, including Simvastatin, Ketoprofen, griseofulvin, ibuprofen, ketoconazole, and carbamazepine, which exhibit high permeability but poor solubility. A potential strategy to improve the solubility and bioavailability of these drugs is the utilization of nanosuspensions.
This study investigates the application of nanosuspension technology to enhance the solubility of Ketoprofen, a BCS Class II drug. By reducing the drug's particle size within the nanosuspension, solubility is improved, leading to increased bioavailability and optimized therapeutic efficacy. The research includes in vitro and in vivo experiments to evaluate the drug release profiles and bioavailability of Ketoprofen-loaded nanosuspensions.
Significant findings from this research include the demonstration of improved bioavailability and enhanced drug release properties achieved with the nanosuspension formulation. In vitro studies show increased drug dissolution rates and improved release profiles compared to conventional formulations. In vivo experiments reveal enhanced pharmacokinetic parameters and therapeutic effectiveness of Ketoprofen when administered through the nanosuspension.
These results highlight the potential of nanosuspensions as an efficient drug delivery system for BCS Class II drugs, addressing their solubility limitations and improving their bioavailability. The findings contribute to the development of novel strategies in pharmacology for enhancing drug solubility and therapeutic outcomes. Overall, this research emphasizes the significance of nanosuspension technology in optimizing the delivery of BCS Class II drugs and offers valuable insights for future formulation development and therapeutic applications.
Keywords: Ketoprofen, Nanosuspensions, Ultrasonication, Precipitation, Dissolution rate, Oral bioavailability.
THE INFLUENCE OF FOREIGN OWNERSHIP, INSTITUTIONAL OWNERSHIP, INDEPENDENT COMMISSIONERS, AND FINANCIAL DISTRESS TO STOCK PRICE WITH ACCOUNTING CONSERVATISM AS A MODERATION VARIABLE
Authors: Firmansyah Andi , Syarifuddin  , Darmawati  
Published: June 2023

This study aims to analyze the influence of Foreign Ownership, Institutional Ownership, Independent Commissioners, and Financial Distress using the disclosure of Accounting Conservatism as a moderating variable. Data collection was obtained from the annual financial reports of Pharmacies listed on IDX 2017 – 2021 period, totaling 30 companies. The sampling technique used purposive sampling because the sample selection was based on the assessment of some of the characteristics of the sample members, which adjusted to the researcher's intentions. Using secondary data on the official IDX website (www.idx.co.id) and the official website of each company. The data analysis method used a special application of multiple linear regression analysis using Moderated Regression Analysis (MRA) with a quantitative approach. The study results show that foreign ownership and independent commissioners do not affect stock prices. Institutional ownership and financial distress have a significant effect on stock prices. Foreign ownership and independent commissioners influence share prices moderated by accounting conservatism. Institutional ownership and financial distress do not affect stock prices of pharmaceutical companies moderated by accounting conservatism. From the results of this study, it is hoped that pharmaceutical sub-sector companies will consider financial reports in carrying out their operating activities. In addition, investors can be used as a tool that provides additional information.
The blood motif in culture-forming narratives: Morphology and semantics
Authors: Danišová Nikola , Klimková Simona 
Published: June 2023

AbstractThe paper seeks to explore the motif of blood, as it appears in various forms in all civilizational and cultural areas. Based on the genre- and culturally diverse texts from the material sample, the authors will present the basic and plot-motif stable forms of the blood motif in ancient culture-forming narratives and outline their archetypal significance.
Breach of a treaty as a cause for its termination and the ratio with international responsibility
Authors: Shqarri Fjorda , Jella Anita 
Published: June 2023

AbstractTreaties as instruments for establishing legal relations between the subjects of international law are acts which can both create a relationship and extinguish it. On the other hand, despite the fact that the parties to a treaty enter into this relationship with the good will that it will last in time and the treaty will be implemented, for various reasons it may happen that the parties are no longer interested in being bound by this treaty. For this reason, the Vienna Convention on the Law of Treaties has provided for ways to terminate the legal force of a treaty. One of these foreseen ways is the breach of the treaty by one of the parties, which must be said, is a way that has found application and is being implemented even today.This paper aims that, relying on a qualitative methodology, based on research in literature and relevant legislation, to analyze the breach of the treaty as a reason for its termination, the types of breaches and the systems proposed by the 1969 Vienna Convention as well as the consequences of breaches of the treaty and a comparative overview with international responsibility.As an expected result of this research, is the conclusion that not every breach of a treaty is a cause for the termination of its legal force and that there are differences between the consequences of the termination of the treaty as a result of a breach by the parties and the reactions to breaches by the point of view of international responsibility.
Development of Sustainability Balanced Scorecard: A Case Study from Apparel Industry Sri Lanka
Authors: Mohanaraj Rathani , Dissanayake Hiranya , Iddagoda Anuradha , Mendis Oshani 
Published: June 2023

AbstractThis study aims to determine the obstacles the Sri Lankan apparel manufacturing industry faces when implementing sustainable practices and develop a Sustainability Balanced Scorecard to address those obstacles. The apparel export industry is one of Sri Lanka’s most significant contributors to the country’s overall economy. The multiple case study method was employed in conjunction with a qualitative approach in this study. This study also used data triangulation, which comprised both primary and secondary data from interviews and observations. Secondary information was gathered from annual reports and other documents. The population of this study is the apparel export industry and selected three apparel companies as the sample and interviewed nine managers from these companies. The interviewed data were transcribed into the transcript and analyzed through narrative analysis. By considering all the practices in three companies, this research constructed a sustainability balanced scorecard which can be used for other companies to build up their sustainability practices. The main issues identified in this research can be summarized as follows, Manual system of data entering and performance evaluation, there is no sufficient Hazardous Waste Management and disposal facilities in the country, Financial constraints prevent best-in-class equipment and procedures from being implemented. Sri Lanka has no solid waste recycling facilities for its primary waste type, fabric waste. As a final point, this research can be concluded that the regulators and policymakers can use the constructed sustainability balanced scorecard for the policy development on sustainability practices.
Virulence of Two Isolates of Meloidogyne enterolobii (Guava Root-Knot Nematode) from North Carolina on Cotton Lines Resistant to Southern Root-Knot Nematode (M. incognita) and Reniform Nematode (Rotylenchulus reniformis)
Authors: Gaudin Amanda G. , Wubben Martin J. , McCarty Jack C. , Jenkins Johnie N. 
Published: June 2023

Abstract

Meloidogyne enterolobii [the guava root-knot nematode (RKN)] is an emerging plant-parasitic nematode that poses a threat to Upland cotton (Gossypium hirsutum) production in the southeastern United States. Like other RKN spp., M. enterolobii has a wide host range and proven ability to overcome resistance sources that have helped protect crops from other Meloidogyne spp., including the southern RKN (Meloidogyne incognita). In this study we evaluated the virulence of two North Carolina M. enterolobii isolates on Upland cotton germplasm lines having resistance quantitative trait loci (QTL) to RKN (M240 RNR, MRk-Rn-1) and/or reniform nematode (Rotylenchulus reniformis) (M713 Ren1, MRk-Rn-1) in comparison to their susceptible recurrent parents (DPL61, SG747). Multiple assays using eggs or J2 as inoculum demonstrated that both isolates reproduced equally well on all germplasm lines, producing reproductive factor (RF) values ≥ 6 on the otherwise nematode-resistant lines. Measurements of seedling growth in control and inoculated containers suggested that existing nematode-resistance QTL may offer a level of tolerance to M. enterolobii infection that should be further explored in greenhouse and field environments. Meloidogyne enterolobii infection of SG747 and MRk-Rn-1 showed nearly identical stages of symptom and nematode development over a time-course of 24 days. These data demonstrate that existing RKN and RN resistance QTL available in elite cotton varieties to producers are most likely insufficient in preventing yield loss due to M. enterolobii and that future research should focus on (i) understanding the M. enterolobii–cotton interaction at the molecular level, and (ii) screening novel germplasm collections to identify resistance loci.
Effect of the Small Field of View and Imaging Parameters to Image Quality and Dose Calculation in Adaptive Radiotherapy
Authors: Ubaidillah Allam , Fauzia Annisa Rahma , Purnomo Adi Teguh , Nasution Nuruddin , Wibowo Wahyu Edy , Pawiro Supriyanto Ardjo 
Published: June 2023

Abstract

Background
The use of cone beam computed tomography (CBCT) for dose calculation in adaptive radiotherapy has been investigated in many studies. Proper acquisition and reconstruction of preset parameters could improve the accuracy of dose calculation based on CBCT images. This study evaluated the impact of the modified image acquisition and preset reconstruction parameter available in X-Ray Volumetric Imaging (XVI) to improve CBCT image quality and dose calculation accuracy.

Materials and methods
Calibration curves were generated by scanning the CIRS phantom using CBCT XVI Elekta 5.0.4 and Computed Tomography (CT) Simulator Somatom, which served as CT image reference. Rando and Catphan 503 phantoms were scanned with various acquisition and reconstruction parameters for dose accuracy and image quality tests. The image quality test is uniformity, low contrast visibility, spatial resolution, and geometrical scale test for each image by following the XVI image quality test module.

Results
Acquisition and reconstruction parameters have an impact on the Hounsfield Unit (HU) value that is used as the HU-Relative Electron Density (RED) calibration curve. The dose difference for all the calibration curves was within 1% and passed the gamma passing rate. Images acquired using 120 kVp, F1 (with Bowtie Filter), and 50 mA (F1-120-50-10) scored the highest Gamma Index (GI) of 98.5%. For the image quality test, it scored 1.20% on the uniformity test, 2.14% on the low contrast visibility test, and 11 lp/cm on the spatial resolution test. However, F1-120-50-10 reconstructed with different reconstructions scored 3.83% and 4 lp/cm in contrast and spatial resolution test, respectively.

Conclusion
CBCT reconstruction parameters work as a scatter correction. It could improve the dose accuracy and image quality. Nevertheless, without adequate CBCT acquisition protocols, it would produce an image with high uncertainty and cannot be fixed with reconstruction protocols. The F1-120-50-10 protocols generate the highest dose accuracy and image quality.
أسس التحول القضائي
Authors: Saadullah Shireen Ahmed , Mohemmed Salih Al-Sherefany Ibrahim 
Published: June 2023

الملخص
التحول في أحكام القضاء الدستوري يعد وسيلة فنية وقائية وإصلاحية للدستور بدلاً من الإلتجاء إلى التعديل الدستوري. وتتمثل فلسفته في حماية الدستوروتحقيق مفهوم الدولة القانونية؛ ذلك في جعل الدستور يواكب التطور الدائم في الحياة، فالواقع في تطور مستمر وقد تبقى نصوص القانون عاجزة أمام هذا التطور وبذلك يعد التحول الوسيلة التي يلجأ اليها القاضي للعدول عن المبادئ التي تضمنتها الاحكام السابقة والتي اصبحت لاتلائم الواقع الجديد، كما إن القضاء الدستوري المقارن و القضاء الدستوري العراقي بشكل خاص، يتجه حالياً نحو التوسع من دائرة التحول في أحكامه، فحقيقة كون الاحكام الدستورية غير قابلة للطعن تجعل من عملية التحول القضائي الدستوري ذات اهمية بارزة، وخصوصاَ ان القضاء الدستوري قد يقضي في مسألة دستورية بطريقة غير صحيحة،الأمر الذي يتطلب بيان الأساس القانوني لهذا التحول. فهدف البحث يكمن في محاولته لوضع أسس واضحة المعالم لهذا العمل القانوني في إطار القضاء الدستوري.
ويلجأ القاضي إلى التحول بإرادته، وهذا هو الأصل وقد يحدث التحول بسبب تغيير نص القانون. إلا أن التحول القضائي الدستوري يحقق النتائج المرجوة منه إذا كان إرادياً يرجع إلى حدوث تغيير في الواقع.
فالتفسير المعاصر للدستور هو الذي يبرر الأعتراف للقاضي الدستوري بالحق في التحول. ولا يعد التحول غاية في ذاتها، بل وسيلة لأداءالقاضي للمهمة المسندة إليه بإيراد تفسير قادر على إيجاد الحل للمسألة المعروضة عليه.
إن التحول يجب أن لا ينطوي على هدر لأصل الدستور ويستخلص كنتيجة طبيعية لتطور رؤية القاضي لموضوع معين وبالتالي يرتب اّثاراَ إيجابية تدعم الحقوق والحريات ولا يفرط القاضي في إستخدامه بحيث يهدد إستقرار المراكز القانونية.
المحكمة الإتحادية العليا العراقية تحولت عن أحكامها من خلال قيامها بتفسير نصوص الدستور ويتوقع أن تتوسع في تحولها لطبيعة ومضمون دستور 2005النافذ، إلا إنه لابد أن يكون التحول مبرراً لتأكيد المشروعية الدستورية وضمان أكبر للحقوق. ونقترح عليها، في حال عرض دعاوي عليها إن تتأمل المبادئ المستقرة عالمياً في المحاكم الدستوية وأهمها المحكمة العليا في أمريكا، بإعتبارها قد إكتسبت خبرة قديمة في هذا المجال.
Personal Branding Melalui Rational Emotive Behavior Therapy Untuk Meningkatkan Kebermaknaan Hidup
Authors: Azzahra Ajeng Suci , Japar Muhammad , Lianasari Dewi 
Published: June 2023

The meaning of life is one of the important things in an individualsâ€™s life. The meaning of life can be increased through several efforts, one of which is by maximing the abilities, potential, and talents possessed, including developing personal branding.Â The purpose of this study is to assist individuals in developing personal branding through Rational Emotive Behavior Therapy to increase the meaning of life. The research methoud use is a pre-experimental one group pretest posttest design with a sampling technique that is simple random sampling. The result showed that group counseling for the development of personal branding thrrough Rational Emotive Behavior Therapy was effective in increasing the meaning of life, that the significance value asymp sig (2-tailed) of Paired Sample T-test is 0,001 < 0,05.
Speech Features in Food Endorsement of Indonesian Influencers: a Study of Language and Gender
Authors: Ilmi Assayyidah Bil Ichromatil , Arimi Sailal 
Published: June 2023

This study aims to identify the speech features employed by male and female influencers while promoting food. This research decided to apply a qualitative method, specifically in the form of a case study. Meanwhile, the researchers chose observation through social media, namely Instagram, as the data collection process. The data analysis consists of three stages, such as reduction, presentation, and conclusion. The researchers found that the female influencers use speech features are intensifier, emphatic stress, tag question, rising intonation, empty adjectives, specialized, hypercorrect grammar, super polite forms, avoidance of strong swear, and one form that belongs to the men known as command and directive. Meanwhile, the speech features employed by the men are command and directive, swearing and taboo words, compliments, and theme, and three forms of speech feature that belong to women, which are intensifier, empty adjective, and emphatic stress. The finding of this study is that both genders are not constantly with their own speech features. Both genders also applied speech features that belong to the opposite gender while doing promotion, although the language features of each gender dominate the respective results. AbstrakPenelitian ini bertujuan mengidentifikasi fitur tuturan yang digunakan oleh influencer pria dan wanita saat melakukan promosi makanan. Penelitian ini menggunakan metode kualitatif, khususnya dalam bentuk studi kasus. Penulis memilih observasi melalui salah satu media sosial, yakni Instagram, pada proses pengumpulan data. Proses analisis data terdiri atas tiga tahap, yaitu reduksi, penyajian, dan penarikan simpulan. Penulis menemukan bahwa para influencer wanita menggunakan fitur ucapan yang intensif, penekanan tegas, tanda pertanyaan, intonasi tinggi, kata sifat kosong, kata khusus, tata bahasa yang berlebihan, bentuk sangat sopan, menghindari umpatan yang kuat, dan satu bentuk milik pria yang dikenal sebagai perintah dan direktif. Sementara itu, ciri-ciri tuturan yang digunakan oleh influencer laki-laki adalah tuturan perintah dan direktif, umpatan dan kata-kata tabu, pujian, dan tema, serta tiga bentuk tuturan yang dimiliki wanita, yaitu intensifier, kata sifat kosong, dan tekanan empatik. Temuan dari penelitian ini adalah bahwa kedua jenis influencer tidak selalu memiliki fitur bicara mereka sendiri. Mereka juga menerapkan fitur bicara milik lawan jenis saat melakukan promosi meskipun hasilnya didominasi oleh ciri fitur bahasa pada masing-masing gender.