bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk Factors for Development of Invasive Candidiasis in Critically III Patients
Authors: Sedono Rudyanto , Adisasmita Asri C. , Djuwita Ratna , Sjaaf Amal Chalik , Nadjib Mardiati , Syarif Syahrizal , Alisjahbana Bachti , Karuniawati Anis , Wahyuningsih Retno 
Published: March 2023

Background:
Majority of invasive candidiasis in critically ill patients was developed after admission to intensive care unit. The aim of this study was to identify risk factors for development of invasive candidiasis among patients admitted to intensive care unit, especially considering the timing of laboratory, microscopic, and culture examinations.

Materials and Methods:
This was a prospective observational study in which critically ill patients were assessed on the first, fifth, and ninth day since admission to intensive care unit. Potential risk factors were demographic and clinical characteristic, clinical managements profile proportions, laboratory profile (leukocyte, platelet, erythrocyte sedimentation rate, C-reactive protein and procalcitonin), morphological change (from yeast to hypae or pseudohyphae in microscopic examination) and colonization increase (from serial culture examination).

Results:
A total of 115 subjects enrolled in this study. Multivariate analysis identified older age (HR 2.8, 95% CI 0.8–8.9), parenteral nutrition (HR 3.1, 95% CI 0.77–12.3), central venous catheter (HR 1.7, 95% CI 0.43–6.67), corticosteroid (HR 2.8, 95% CI 0.53–14.8), procalcitonin day-5 (HR 3.1, 95% CI 0.89–10.8), morphology change in the axilla and rectal swab (HR 5.1, 95% CI 1.6–18.51), and morphology change and colonization increase in rectal swab day-9 (HR 4.3, 95% CI 1.0–18.02) as independent risk factors of invasive candidiasis.

Conclusion:
In addition to several typical risk factors, procalcitonin test on day-5 as well as serial microscopic and culture examinations were associated with the development of invasive candidiasis, therefore potentially help in the diagnosis and treatment of critically ill patients in intensive care unit.
Subthreshold micropulse 532-nm green laser treatment of acute central serous chorioretinopathy
Authors: Mohamed Asmaa A. , Genaidy Mahmoud M. , Zein Hosny A. 
Published: March 2023

Purpose
The aim of this study was to evaluate the efficacy and safety of 532-nm green subthreshold micropulse laser (GSML) as a treatment for acute central serous chorioretinopathy (CSCR).

Patients and methods
This was a prospective study that included 42 eyes of 42 patients with acute CSCR treated with IRIDEX IQ 532-nm GSML. The study was conducted at Minia University Hospital and Genaidy Ophthalmology Center, Minia, Egypt, between October 2019 and May 2022. All patients were subjected to complete ophthalmological examination, fluorescein angiography, and optical coherence tomography at baseline and each follow-up visit at 1, 3, and 18 months after laser treatment. The outcome measures included the change in best-corrected visual acuity from baseline, optical coherence tomography-measured central macular thickness, as well as the resolution of subretinal fluid (SRF).

Results
The mean baseline LogMAR best-corrected visual acuity was 0.41±0.27 and significantly improved to 0.29±0.17 at 1 month (P=0.001), 0.21±0.14 at 3 months (P=0.0001), and 0.16±0.12 at 18 months (P=0.0001). The mean central macular thickness was 438.8±141.9 μm before treatment with a significant reduction to 352.8±60.6 μm after 1 month (P=0.005), 291.1±55.3 μm after 3 months (P=0.0001), and 241.8±24.5 μm after 18 months (P=0.0001). Regarding the SRF, it was absent in 40 (95.2%) eyes at the 3-month visit, whereas recurrence was present in only two (4.8%) eyes, with no cases of persistent SRF at the last follow-up. No complications were encountered during or after laser treatment.

Conclusions
GSML may be a safe and effective treatment modality for the acute form of CSCR with a low rate of disease recurrence.
Therapeutic pluralism and the politics of disclosure: breast cancer patients’ experiences in public healthcare
Authors: Nyawira Githaiga Jennifer , Swartz Leslie 
Published: March 2023

Background: Despite the widespread utilisation of complementary and or alternative medicine (CAM) by breast cancer patients in low-and-middle-income countries, few disclose CAM use to their physicians.
Objective: This study examines disclosure CAM use among a small sample of women attending a breast cancer clinic in a public health hospital in the Western Cape, South Africa.
Methods: An Interpretative Phenomenological Analysis (IPA) approach was utilised in this study. Semi-structured in-depth interviews were conducted with a convenience sample of 17 women attending a breast clinic in a public hospital.
Results: Non-disclosure of CAM use was attributed to minimal time for patient-doctor interactions due to resource constraints in public health facilities and the superior status accorded to biomedical doctors’ superior knowledge, associated with paternalism, leading to patients’ fear of reproach for using CAM. Consequently, disclosure of CAM only occurred in instances where it was deemed an absolute necessity.
Conclusion: Considering the reality of an overstretched public healthcare system, what may be possible is an active attempt to communicate to patients that doctors are aware that patients may use a range of resources (such as CAM), which is their right, and further, recommend patient disclosure of CAM use to their doctors, because of the possibility of drug interactions and other potentially negative effects.
Keywords: Breast cancer; alternative medicine; South Africa.
Forensic tool for sex prediction- hand dimensions
Authors: Gupta Renu , Kumar Nayyar Ashish , Kumar Gupta Manoj , Lata Bhagat Om 
Published: March 2023

Background: Determination of sex from mutilated body fragments can perform vital role for identification of departed soul.Forensic authority pacts with human identification from the hand measurements which is of prodigious assessment during tragedies, terror attacks and in criminality.
Objective: Present study explored the analytical role of the anthropometric measurements of hand dimensions, find demarking points for male and female, check percentage exactitude of sex determination in Western Indian population.
Methods: The study was piloted on a sample of 504 individuals. All the measurements were taken by standard procedure. Discriminant analysis and demarking points were created for all hand measurements.
Results: Males have a significantly higher values of all measurements than females. The left-hand length measurement unveiled noteworthy sexual dimorphism index (110.80). The higher value of the demarking point labelled as males. The best sexually dimorphic hand dimensions showed the utmost precision left hand length (95% in the male), followed by right hand length (76.1%).
Conclusion: All hand measurements like length, breadth and index are displaying sexual dimorphism, hence they can be used for determination of sex when isolated hand is found.Keywords: Hand measurements; sexual dimorphism; demarking point; discriminant analysis.
Overnutrition and its associated factors among adult human immunodeficiency virus positive patients on antiretroviral therapy, Northwest, Ethiopia
Authors: Sewale Yihenew , Tefera Zewudie Bitew 
Published: March 2023

Background: Anti-retroviral therapy was introduced to treat human immunodeficiency virus patients; comorbidities affecting individuals with human immunodeficiency virus-positive have changed dramatically, with increasing the prevalence of overnutrition.Overnutrition has increased from time to time in people living with the human immunodeficiency virus. However, there is scarce adequate documented evidence regarding nutrition on human immunodeficiency virus
Objective: The study aimed to assess the magnitude of over nutrition and its associated factors among human immunodeficiency virus receiving antiretroviral therapy
Methods: We used a cross-sectional study design to collect data from 422 participants from Debre Markos hospital. We used a systematic sampling technique to select the total number of participants. The outcomes of Data were entered, and coded using Epi-data version 4.1 and analysed using STATA Version 14.1. We performed a multivariable logistic regression model to identify determinants of over-nutrition at a p-value of less than 0.05.
Results: The magnitude of overnutrition was 19.7% (95%CI: 14.6-25.4). Age group > 45 years (AOR: 3.18:95%CI: 1.09, 9.22), being farmer (AOR: 0.068, 95%CI (0.007, 0.611), family size greater than or equal to 4 (AOR: 3.18:95%CI (1.09-9.22), viral load less than 1000 copies/ml (AOR: 4.45 95%CI (1.69-11.76), and use of prophylaxis therapy (AOR: 2.67:95%CI (1.138-6.291) were significantly associated with over nutrition.
Conclusions: In this study one-fifth of Human Immunodeficiency Virus/Acquired Immunodeficiency Virus patients had over nutrition. In this study, the magnitude of overnutrition is high associated with a viral load of fewer than 1000 copies/cell, age greater than 45, and having taken prophylaxis therapy. Therefore, education about lifestyle change, regular monitoring of weight, regular nutritional assessment, and intervention of the existed problems like doing regular exercise is highly recommended.
Keywords: Overnutrition; ART; HIV.
Evaluation of the operational performance of the Nigerian agricultural cooperatives and rural Development bank (nacrdb) in cross river state
Authors: A  Ajah E , B Ohen S , Asuquo A , F Elem G 
Published: March 2023

This study examined the performance of farmers in Nigerian Agricultural Cooperative and Rural Development Bank (NACRD5. in terms of repayment in Cross River State. Specifically the study analyzed lending and loan characteristics, constrants to repayment, repayment performance and compare repayment between crop and poultry farmers. Purposive and random sampling procedures were used to select 270 respondents using both primary and secondary data to accomplish the objectives. Data analyses included the use of mean, frequencies, percentages and
the t-test. The study showed that the institution considered was characterized by untimely delivery of loan owing to complicated. Cumbersome and time consuming procedures in loan processing/ approval decision and amount of loan disbursed. The comparison between crop and poultry producers revealed that crop producers repaid their loan more than their poultry counterparts. The study recommended that timely disbursement policies that increase the accessibility of farmers to loan should be adopted and this would be an effective measure to aid flow of funds into the agricultural sector.
Long non-coding RNA LINC00470 regulates the growth and epithelial-to-mesenchymal transition of human oral cancer cells
Authors: Liu Fengjia , Liu Min , Li Wannan , Ou Yuejian 
Published: March 2023

Purpose: To investigate the role of long non-coding RNA LINC00470 in human oral cancer tissues and cell lines (OC3, SCC9 and CAL27).
Methods: Expression of mRNA was determined by quantitative reverse transcription-polymerase chain reaction (qRT-PCR). Cell viability and proliferation were measured using MTT and EdU assays, respectively, while cell migration and invasion were determined with transwell assay. Protein expression was assayed with western blotting.
Results: There was significant up-regulation of LINC00470 in the cancer tissues and cell lines (OC3, SCC9 and CAL27) (p < 0.05). Silencing of LINC00470 led to significant inhibition of the proliferation and colony-formation potential of the oral cancer cells (p < 0.05). Furthermore, silencing of LINC00470 in oral cancer cell lines caused significant induction of apoptosis, suppression of migration and invasion, and restoration of epithelial-to-mesenchymal transition (EMT).
Conclusion: These results strongly demonstrate the oncogenic role of LINC00470 in oral cancer, thereby suggesting its possible prognostic and therapeutic potential in this lethal malignancy.
The Use of a Single-Time Sit-To-Stand Test in Ambulatory Individuals With Spinal Cord Injury by Primary Health Care Providers
Authors: Amatachaya Sugalya , Khuna Lalita , Amatachaya Pipatana , Wiyanad Arpassanan 
Published: March 2023

BackgroundThe uncertain health care situations, such as that created by the COVID-19 pandemic, has limited hospital access and facilitated a paradigm shift in health care toward an increased demand for standard home visits and community-based rehabilitation services, including by ambulatory individuals with spinal cord injury (SCI).ObjectivesThis 6-month prospective study explored the validity and reliability of a single-time sit-to-stand (STSTS) test when used by primary health care (PHC) providers, including a village health volunteer, caregiver, individual with SCI, and health professional.MethodsEighty-two participants were assessed for the STSTS using four arm placement conditions (arms on a walking device, arms on knees, arms free by the sides, and arms crossed over the chest) and standard measures, with prospective fall data follow-up over 6 months. Thirty participants involved in the reliability study were also assessed and reassessed for the ability to complete the STSTS conditions by PHC providers.ResultsOutcomes of the STSTS test, except the condition with arms on a walking device, could significantly discriminate lower extremity muscle strength (LEMS) and mobility of the participants (rpb = −0.58 to 0.69) with moderate concurrent validity. Outcomes of the tests without using the arms also showed moderate to almost-perfect reliability (kappa = 0.754–1.000) when assessed by PHC raters.ConclusionThe findings suggest the use of an STSTS with arms free by the sides as a standard practical measure by PHC providers to reflect LEMS and mobility of ambulatory individuals with SCI in various clinical, community, and home-based settings.
Partial Vs Full Range of Motion Resistance Training: A Systematic Review and Meta-Analysis
Authors: Wolf Milo , Androulakis-Korakakis Patroklos , Fisher James , Schoenfeld Brad , Steele James 
Published: March 2023

Abstract
Background: Range of motion (ROM) during resistance training is of growing interest and is potentially used to elicit differing adaptations (e.g. muscle hypertrophy and muscular strength and power). To date, attempts at synthesising the data on ROM during resistance training have primarily focused on muscle hypertrophy in the lower body.
Objective: Our aim was to meta-analyse and systematically review the effects of ROM on a variety of outcomes including hypertrophy, strength, sport, power and body-fat type outcomes. Following pre-registration and consistent with PRISMA guidelines, a systematic review of PubMed and SportsDISCUS was performed. Data was extracted and a Bayesian multi-level meta-analysis was performed. A range of exploratory sub-group and moderator analyses were performed.
Results: The main model revealed a trivial SMD (0.12; 95% CI: –0.02, 0.26) in favour of full ROM compared to partial ROM. When grouped by outcome, SMDs all favoured full ROM, but SMDs were trivial to small (all between 0.05 to 0.2). Sub-group analyses suggested there may be a muscle hypertrophy benefit to partial ROM training at long muscle lengths compared to using a full ROM (–0.28; 95% CI: –0.81, 0.16). Analysis also suggested the existence of a specificity aspect to ROM, such that training in the ROM being tested as an outcome resulted in greater strength adaptations. No clear differences were found between upper- and lower-body adaptations when ROM was manipulated.
Conclusions: Overall, our results suggest that using a full or long ROM may enhance results for most outcomes (strength, speed, power, muscle size, and body composition). Differences in adaptations are trivial to small. As such, partial ROM resistance training might present an efficacious alternative for variation and personal preference, or where injury prevents full-ROM resistance training.
EVALUATION OF THE EFFICIENCY OF FEMIDA, OD HERBICIDE APPLIED TO WINTER WHEAT IN SPRING
Authors: Soroka L. I. , Soroka S. V. , Pestereva A. S. 
Published: March 2023

The paper presents the results of the research on biological and economic efficiency of the new herbicide Femida, OD (2,4 D-acid, 320 g/l of 2-ethylhexyl ester + 4.2 g/l of chlorsulfuron) produced by Schelkovo Agrohim, Ltd., Russia. It’s established that with protection of winter wheat at the tillering stage in spring the reduction of infestation with annual and perennial weeds amounts to more than 85 %, in particular, blind weed,
lamb’s-quarters, field scorpion grass, dead beans – 100 %; wild camomile – 85,4–100 %, scratch grass – 78,3–100 %, blue bottle flower – 95,5–100 %, field violet – 65,7–80.7 %, field sow thistle – 91,7–100 %.
PENGARUH KEBIJAKAN PAJAK DALAM MENINGKATKAN KEPATUHAN WAJIB PAJAK DI MASA PANDEMI COVID-19
Authors: Halim Olivia Lawrencia 
Published: March 2023

Latar belakang: Hadirnya pandemi Covid-19 telah membawa dampak yang begitu besar di berbagai aspek kehidupan sehari-hari, terutama ekonomi, sosial dan politik di dunia sehingga perputaran roda perekonomian di Indonesia menjadi sangat lambat. Dampak yang ditimbulkan oleh pandemi Covid-19 di bidang ekonomi juga berimbas kepada pendapatan negara. Salah satunya adalah negara Indonesia yang sebagian besar sumber pendapatan negara adalah melalui penerimaan pajak. Oleh sebab itu, kesadaran akan pentingnya peranan pajak sebagai sumber pendapatan terbesar negara, maka pemerintah terus melakukan upaya peningkatan kas negara dengan dibentuknya kebijakan di sektor perpajakan guna menunjang pertumbuhan ekonomi nasional. hal tersebut juga memerlukan adanya kesadaran masyarakat untuk membayar pajak, terkhususnya wajib pajak di masa pandemi ini.
Metode penelitian: Metode penelitian yang digunakan adalah studi kepustakaan. Studi kepustakaan merupakan suatu kegiatan menelaah bahan pustaka guna memperoleh informasi yang relevan dengan objek penelitian. Adapun sumber bahan hukum yang digunakan berupa bahan hukum primer dan bahan hukum sekunder. Bahan hukum primer adalah bahan pustaka yang meliputi peraturan perundang-undangan nasional yang relevan dengan topik penelitian, sedangkan bahan hukum sekunder adalah bahan yang memiliki korelasi dengan bahan hukum primer yang diperoleh dari beberapa karya ilmiah, internet, dan jurnal yang dapat mendukung penelitian ini.
Hasil penelitian: Menurut data Kemenkeu, realisasi penerimaan pajak telah mencapai setidaknya 88,3% dari target APBN yang sebesar Rp1.485 triliun. Selain itu, menurut hasil penelitian Supriyati (2018) yang didasarkan pada motivational posture, menunjukkan bahwa kesadaran dari diri individu berpengaruh sangat kuat terhadap perilaku patuh atau tidaknya dalam melaksanakan kewajibannya. Salah satu aspek terpenting dalam meningkatkan kepatuhan wajib pajak adalah strategi pemeriksaan dan pemberian sanksi pajak.
Kesimpulan: Pandemi Covid-19 tidak hanya berdampak pada ekonomi tetapi juga terhadap perpajakan. Realisasi penerimaan pajak melonjak hingga 54,2% pada September 2022. Kesadaran wajib pajak berpengaruh besar pada perilaku patuhnya sendiri. Adapun strategi upaya dalam meningkatkan kepatuhan wajib pajak: memperbaiki pelayanan perpajakan, meningkatkan jumlah tenaga pemeriksa di DJP, melakukan sosialisasi dan edukasi tentang perpajakan, serta melakukan internalisasi nilai moral dan integritas petugas pajak dalam menjalankan tugasnya.
Effectiveness Of Multifaceted Care Bundle Approach To Reduce Device Associated Infection (Dai) In Critical Care Unit (Ccu) In A Multi Specialty Hospital, Mangaluru
Authors: Sookshma Crasta T , DR.Larissa Martha Sams  
Published: March 2023

Device-associated infections (DAI) can cause major medical and economic sequelae. Multifaceted care bundle is considered as an important part of routine nursing activity, not only as a measures DAI prevention, but as a crucial treatment with a profound effect on the patients general health.
Objectives

To measure the Device associated infection status of CLABSI, CAUTI, and VAP in pre implementation phase according to HAI surveillance guidelines.
To determine the compliance status of health care workers of care bundles on prevention and care of device associated infections in CCU in Phase III.
To evaluate the effectiveness of multifaceted care bundle approach on device associated infections status of CLABSI, CAUTI, & VAP in CCU
To find the risk of DAI in patients in the Post implementation phase (Phase III)

Methods: An experimental approach was adopted to study the effectiveness of multifaceted care bundle approach to reduce device associated infection (DAI) in critical care unit (CCU) in a multispecialty hospital, Mangaluru. Universal sampling technique was adopted to select the 472 sample retrospectively (MRD and HIC records of DAI patients of critically care units) and 409 samples as prospectively (current critically ill patients) then implementation of bundle was done and post implementation evaluation done.
Results: While comparing pre and post implementation phases, it is found that there was reduction in CAUTI rate /1000 catheter days and CLASBI rate/1000 central line days from Phase I to phase III and increase in VAP rate /1000 ventilator days from Phase I to phase III. Increase in device utilization ratio of CAUTI and CLASBI from Phase I to III and reduction in VAP device utilization ratio from Phase I to III, also observed that during pre-implementation phase, the VAP rate, CLABSI rate and CAUTI rate for all the ICU’s taken together were 134.37/1000 ventilator days, 412/1000 central line days, and 332.92/1000 urinary catheter days, respectively. However, during the post implementation the rates reduced into 133.92, 287.98, and 242 per 1000 device days respectively. There was a month wise decreasing trend of VAP rate, CLABSI rate, and CAUTI rate during the study period.
In males CAUTI, CLABSI AND VAP rates were reported highest in the both Phases (I and III) and CAUTI, CLABSI and VAP difference in both Phases was not statistically significant according to age and gender (p=0.500) .Highest number of CAUTI was reported in Phase I compared to Phase III .Total number of device days were more (352) for CAUTI whereas 340 ventilator days for VAP, 292 central line days in the Phase I. While comparing both Phases significant difference was found in CAUTI (0.0017) CLASBI (0.002) and VAP (0.0016 ).
Conclusion: From the findings of the study it can concluded that multifaceted care bundle significantly reduced DAIs in critically ill patients
Phytoconstituents Screening, TLC, And GC-MS Analysis Of Barleria Cristata Linn. Leaves Methanolic Extract
Authors: Harini V, Kumar P.R, Thirumal M  
Published: March 2023

Barleria cristata Linn is an ornamental plant that grows on the sides of roads in India, China, and other countries. This plant belongs to the family Acanthaceae. In India, it is used as herbal medicine and is called Kala Bansa. It has an ancient legacy of application in folk medicine, particularly for the treatment of tuberculosis and snake bites. The purpose of the present study was a preliminary phytochemical analysis, Thin-Layer Chromatography (TLC) analysis and Gas chromatography-mass spectroscopy (GCMS) analysis of the methanol extract of Barleria cristata Linn leaves. The preliminary phytochemical screening finding revealed compounds like Alkaloids, Glycosides, Flavonoids, Carbohydrates, Proteins, and amino acids, and Reducing sugars. Thin-layer chromatography (TLC) of the methanolic extract was executed for 5 essential phytoconstituents Alkaloids, Flavonoids, Saponins, Glycosides, and Triterpenoids. The leaf extract of this plant was analyzed using GCMS. This report revealed the 15 compounds. The bioactive chemicals were found by comparing the retention time and peak area with the literature. Barleria cristata possess various medicinal properties, so more research must be done on its traditional claims.