bluuebunny/crossref_metadata_2025_split huggingface dataset:
Solving the comfort-retrofit conundrum through post-occupancy evaluation and multi-objective optimisation
Authors: Yu Chuan-Rui , Liu Xuan , Wang Qian-Cheng , Yang Dujuan 
Published: May 2023

Developing appropriate building retrofit strategies is a challenging task. This case study presents a multi-criteria decision-supporting method that suggests optimal solutions and alternative design references with a range of diversity at the early exploration stage in building retrofit. This method employs a practical two-step method to identify critical comfort and energy issues and generate optimised design options with multi-objective optimisation based on a genetic algorithm. The first step is based on a post-occupancy evaluation, which cross-refers benchmarking and correlation and integrates them with non-linear satisfaction theory to extract critical comfort factors. The second step parameterises previous outputs as objectives to conduct building simulation practice. The case study is a typical post-war highly glazed open-plan office in London. The post-occupancy evaluation result identifies direct sunlight glare, indoor temperature, and noise from other occupants as critical comfort factors. The simulation and optimisation extract the optimal retrofit strategies by analysing 480 generated Pareto fronts. The proposed method provides retrofit solutions with a criteria-based filtering method and considers the trade-off between the energy and comfort objectives. The method can be transformed into a design-supporting tool to identify the key comfort factors for built environment optimisation and create sustainability in building retrofit. Practical application: This study suggested that statistical analysis could be integrated with parametric design tools and multi-objective optimisation. It directly links users’ subjective opinions to the final design solutions, suggesting a new method for data-driven generative design. As a quantitative process, the proposed framework could be automated with a program, reducing the human effort in the optimisation process and reducing the reliance on human experience in the design question defining and analysis process. It might also avoid human mistakes, e.g. overlooking some critical factors. During the multi-objective optimisation process, large numbers of design options are generated, and many of them are optimised at the Pareto front. Exploring these options could be a less human effort-intensive process than designing completely new options, especially in the early design exploration phase. Overall, this might be a potential direction for future study in generative design, which greatly reduce the technical obstacle of sustainable design for high building performance.
Beck Hopelessness Scale-20: Dimensionality and Nomological Validity Among Colombian School-Age Adolescents
Authors: Pineda-Roa Carlos Alejandro , Campo-Arias Adalberto , Bello-Villanueva Ana Mercedes 
Published: May 2023

To establish the validity of the BHS-20, a sample of 2064 adolescent students aged 14 and 17 years (M = 15.61, SD = 1.05) were invited to participate in the research. Cronbach’s alpha (α) and McDonald’s omega (ω) were computed to evaluate the internal consistency. Confirmatory factor analysis was used to test the dimensionality of the BHS-20. The Spearman correlation ( r s) with depressive symptoms and risk of suicide scores of the Plutchik Suicide Risk Scale were computed to explore the nomological validity. The BHS-20 showed a high internal consistency (α = .81, ω = .93), an adequate one-dimensional structure with an excellent adjustment [χ2 S-B = 341, df = 170, p < .01, Comparative Fit Index = .99, RMSEA = .03] and acceptable nomological validity with depressive symptoms ( r s = .47, p < .01) and scores for suicide risk ( r s = .33, p < .01). In conclusion, current results suggest that the BHS-20 demonstrates validity and reliability among Colombian adolescent students.
Developmental differences in reported overparenting, autonomy, and glucose monitoring within a medical specialty camp context
Authors: Gagnon Ryan J. , Garst Barry A. , Heffington Leslie E. 
Published: May 2023

Developmentally inappropriate and excessive parenting can manifest at higher levels in children with Type 1 diabetes (T1D). A child’s age, level of T1D training, and time since T1D diagnosis have been associated with higher levels of developmentally excessive parenting (i.e., overparenting), lower rates of autonomy granting, and lower rates of continuous glucose monitoring (CGM). Utilizing a structural equation model, the present study examined these associations with data collected from a medical specialty camp (MSC) serving 262 youth with T1D. Respondents primarily identified as female (59.5%), were an average 13.83 years old, and had attended the MSC for an average of 3.72 years. Respondents had an average of 5.95 years since T1D diagnosis, an average of 2.62 years utilizing a CGM, reported checking their CGM data an average of 12.75 times per day, and an average of 12.02 parent CGM checks per day. As youth age increased, rates of overparenting decreased. Similarly, youth with more MSC experience reported lower rates of overparenting. Contrary to the study hypotheses, overparenting had a positive effect on autonomy granting. Finally, a negative relation was found between years with T1D and average CGM checks, consistent with the broader T1D literature where adherence to diabetes management tends to decline in parallel with youth experience level managing T1D.
Development and validation of a nomogram for predicting prognosis of high-grade chondrosarcoma: A surveillance, epidemiology, and end results-based population analysis
Authors: Sun Yu , Ouyang Chenxi , Zhang Yu , Li Yong , Liu Yang , Jiang Ming , Nong Luming , Gao Gongming 
Published: May 2023

Background The incidence of chondrosarcoma is increasing every year, and the treatment and prognosis of patients with high-grade chondrosarcoma are becoming more and more important. Nomogram is a tool that can quickly and easily predict the overall survival of tumor patients. Therefore, the development and validation of a nomogram to predict overall survival in patients with high-grade chondrosarcoma was desired. Methods We retrospectively collected 396 patients with high-grade chondrosarcoma from the Surveillance, Epidemiology, and End Results (SEER) database from 2004 to 2015. Randomly divided into model and validation groups, the best cut-off values for age and tumor size grouping were derived by using X-tile software. Then, independent prognostic factors for high-grade chondrosarcoma were derived by SPSS.26 univariate and multivariate Cox analyses analysis in the model group, and the model was evaluated by using R software, using C-indix and ROC curves, and finally these independent prognostic factors were included in Nomogram. Results 396 patients were randomly assigned to the modelling group (n = 280) or the validation group (n = 116). Age, tissue-type, tumor size, AJCC stage, regional expansion and surgery were identified as independent prognostic factors ( p < 0.05) which further combined to construct a nomogram. The C-index of internal validation for overall survival(OS) was 0.757, while the C-index of external validation for overall survival(OS) was 0.832. Both internal and external calibration curves show a good agreement between nomogram prediction and actual survival. Conclusion In this study, we established age, tumour size, AJCC stage, tissue type, surgery and tumor extension as independent prognostic factors for high-grade chondrosarcoma and constructed a nomogram to predict 3- and 5-year survival rates for high-grade chondrosarcoma.
The Effect of Methylphenidate Treatment on Olfactory Function in Children and Adolescents With ADHD
Authors: Mercan Isik Cansu , Uzun Cicek Ayla , Altuntas Emine Elif , Bora Adem , Sari Seda Aybuke , Akkus Serdar 
Published: May 2023

Objective: This study aimed to research whether there is an olfactory disorder in ADHD, and if so, what is the effect of methylphenidate on this condition. Method: This is a cross-sectional study aiming to evaluate olfactory threshold, identification, discrimination and threshold, discrimination, and identification (TDI) scores in 109 children and adolescents, 33 of whom have ADHD without medication, 29 with ADHD with medication and 47 control groups. Result: In the post hoc tests, the mean odor discrimination test, the mean odor identification test, and the mean TDI scores of the unmedicated ADHD group were significantly lower than those of the other two groups, and that the mean odor threshold test scores of the medicated ADHD group were significantly lower than those of the control and unmedicated groups. Conclusion: Olfactory function could be a useful tool to monitor treatment effects and may be a promising candidate as a biomarker in ADHD.
A pro-inflammatory diet in people with multiple sclerosis is associated with an increased rate of relapse and increased FLAIR lesion volume on MRI in early multiple sclerosis: A prospective cohort study
Authors: Saul Alice M , Taylor Bruce V , Blizzard Leigh , Simpson-Yap Steve , Oddy Wendy H , Shivappa Nittin , Hébert James R , Black Lucinda J , Ponsonby Anne-Louise , Broadley Simon A , Lechner-Scott Jeanette , van der Mei Ingrid , Lucas Robyn M , Dear Keith , Dwyer Terry , Broadley Simon , Kilpatrick Trevor , Williams David , Shaw Cameron , Chapman Caron , Coulthard Alan , Pender Michael P , Valery Patricia 
Published: May 2023

Background: A pro-inflammatory diet has been posited to induce chronic inflammation within the central nervous system (CNS), and multiple sclerosis (MS) is an inflammatory disease of the CNS. Objective: We examined whether Dietary Inflammatory Index (DII®)) scores are associated with measures of MS progression and inflammatory activity. Methods: A cohort with a first clinical diagnosis of CNS demyelination was followed annually (10 years, n = 223). At baseline, 5- and 10-year reviews, DII and energy-adjusted DII (E-DIITM) scores were calculated (food frequency questionnaire) and assessed as predictors of relapses, annualised change in disability (Expanded Disability Status Scale) and two magnetic resonance imaging measures; fluid-attenuated inversion recovery (FLAIR) lesion volume and black hole lesion volume. Results: A more pro-inflammatory diet was associated with a higher relapse risk (highest vs. lowest E-DII quartile: hazard ratio = 2.24, 95% confidence interval (CI) = −1.16, 4.33, p = 0.02). When we limited analyses to those assessed on the same manufacturer of scanner and those with a first demyelinating event at study entry (to reduce error and disease heterogeneity), an association between E-DII score and FLAIR lesion volume was evident (β = 0.38, 95% CI = 0.04, 0.72, p = 0.03). Conclusion: There is a longitudinal association between a higher DII and a worsening in relapse rate and periventricular FLAIR lesion volume in people with MS.
Pronoun comprehension and cross-linguistic influence in monolingual and bilingual children
Authors: Foursha-Stevenson Cass , Nicoladis Elena , Trombley René , Hablado Kurt , Phung Derek , Dallaire Kaley 
Published: May 2023

Aims and objectives/purpose/research questions: Pronoun comprehension can present challenges for young bilingual and monolingual children. The current study aimed to assess cross-linguistic influence (CLI) and pronoun comprehension in early childhood. Several studies have demonstrated the role of overlap across languages and its impact on language development. The present study investigates the influence of the acquisition of another language containing third-person pronouns on pronoun comprehension in English. Additional possible social influences are also discussed. Design/methodology/approach: In addition to the completion of language surveys and vocabulary tests, toddlers and preschoolers were presented with a forced-choice test to identify the pronouns ‘he/she/it’ between a man doll, a woman doll, a ball, and a monkey. Data and analysis: Accuracy in pronoun comprehension was analysed based on age and preschooler’s accuracy was compared across language groups (monolingual in English, bilingual with and without third-person pronouns). Findings/conclusions: Overall, the results demonstrated that, although young toddlers were able to comprehend ‘it’, children struggled with ‘he’ and ‘she’ until 3 years of age. In addition, bilingual preschool children that were learning a language that distinguished between the third-person pronouns, ‘he’ and ‘she’, performed similarly to monolingual English-speaking children and both groups performed better than bilingual children learning a language that did not distinguish between ‘he’ and ‘she’. The findings are discussed in the context of within- and between-language factors that can impact comprehension. Originality: Most recent research on early pronoun development involves production. This study presents evidence of early pronoun comprehension and investigates the role of CLI in this difficult, yet common component of language. Significance/implications: The results suggest that learning a language with different features can negatively impact pronoun comprehension in another language. The findings are discussed in the context of an integrated system for bilinguals.
Outcomes of the Gore® Excluder® Iliac Branch Endoprosthesis Using Self Expanding or Balloon-Expandable Stent Grafts for the Internal Iliac Artery Component
Authors: Cortolillo Nicholas S. , Guerra Andres , Murphy Eric , Hoel Andrew W. , Eskandari Mark K. , Tomita Tadaki M. 
Published: May 2023

Objective: The GORE® EXCLUDER® Iliac Branch Endoprosthesis (IBE; W.L. Gore & Associates, Flagstaff, Arizona) was developed to be used in combination with a self-expanding stent graft (SESG) for the internal iliac artery (IIA) bridging stent. Balloon-expandable stent grafts (BESGs) are an alternative for the IIA, offering advantages in sizing, device tracking, precision, and lower profile delivery. We compared the performance of SESG and BESG when used as the IIA bridging stent in patients undergoing EVAR with IBE. Methods: This is a retrospective review of consecutive patients who underwent EVAR with IBE implantation at a single center from October 2016 to May 2021. Anatomic and procedural characteristics were recorded via chart review and computed tomography (CT) postprocessing software (Vitrea® v7.14). Devices were assigned to SESG vs. BESG groups based on the type of device landing into the most distal IIA segment. Analysis was performed per device to account for patients undergoing bilateral IBE. The primary endpoint was IIA patency, and secondary endpoint was IBE-related endoleak. Results: During the study period, 48 IBE devices were implanted in 41 patients (mean age 71.1 years). All IBE devices were implanted in conjunction with an infrarenal endograft. There were 24 devices in each of the self-expanding internal iliac component (SE-IIC) and balloon-expandable internal iliac component (BE-IIC) groups. The BE-IIC group had smaller diameter IIA target vessels (11.6±2.0 mm vs. 8.4±1.7 mm, p<0.001). Mean follow-up was 525 days. Loss of IIA patency occurred in 2 SESG devices (8.33%) at 73 and 180 days postprocedure, and in zero BESG devices, however, this difference was not statistically significant (p=0.16). There was 1 IBE-related endoleak requiring reintervention during the study period. A BESG device required reintervention due to Type 3 endoleak at 284 days. Conclusions: There were no significant differences in outcomes between SESG and BESG when used for the IIA bridging stent in EVAR with IBE. The BESGs were associated with using 2 IIA bridging stents and were more often deployed in smaller IIA target arteries. Retrospective study design and small sample size may limit the generalizability of our findings. Clinical Impact This series compares postoperative and midterm outcomes of self expanding stent grafts and balloon expandable stent grafts (BESG) when used as the internal iliac stent graft as part of a Gore® Excluder® Iliac Branch Endoprosthesis (IBE). With similar outcomes between the two stent-grafts, our series suggests that some of the advantages of BESG, device sizing, tracking, deployment, and profile, may be able to be leveraged without impacting the mid-term performance of the IBE.
Optimal cutoff value of carotid stump pressure for determining the need for a carotid shunt in carotid artery endarterectomy
Authors: Demir Tolga , Bektas Nilufer , Kasapoglu Begum O , Acar Sevinc Sultan , Balta Basi Nermin , Ozcelik Fatih , Yalaz Tekan Ulgen , Koramaz Ismail 
Published: May 2023

Objective This study was conducted to identify the diagnostic value of carotid stump pressure for determining the need for a carotid artery shunt in patients undergoing carotid artery endarterectomy. Materials and methods Carotid stump pressure was prospectively measured in all carotid artery endarterectomies performed under local anesthesia between January 2020 and April 2022. The shunt was selectively used when neurological symptoms appeared after carotid cross-clamping. Carotid stump pressure was compared between patients who needed shunting and those who did not. Demographic and clinical characteristics, hematological and biochemical parameters, and carotid stump pressure of the patients with and without shunts were statistically compared. To determine the optimal cutoff value and diagnostic performance of carotid stump pressure for identifying the patients who need a shunt, receiver operating characteristic analysis was performed. Results Overall, 102 patients (61 men and 41 women) who underwent carotid artery endarterectomy under local anesthesia were included, with an age range of 51–88 years. A carotid artery shunt was used in 16 (8 men and 8 women) patients. The carotid stump pressure values of the patients with a shunt were lower than those without a shunt (median (min–max): 42 (20–55) vs 51 (20–104), p < 0.0006). In the receiver operating characteristic curve analysis performed to determine the need for a shunt, the optimal cutoff value of carotid stump pressure was ≤48 mmHg, sensitivity was 93.8%, and specificity was 61.6% (area under the curve: 0.773, p < 0.0001). Conclusion Carotid stump pressure has sufficient diagnostic power to determine the need for a shunt, but it cannot be used alone in the clinical setting. Instead, it can be used in combination with other neurological monitoring methods.
Long-term effect of Helicobacter pylori eradication on colorectal cancer incidences
Authors: Guo Chuan-Guo , Zhang Feifei , Jiang Fang , Wang Lingling , Chen Yijun , Zhang Wenxue , Zhou Anni , Zhang Shutian , Leung Wai K. 
Published: May 2023

Background: There is evidence supporting the association between Helicobacter pylori infection and colorectal cancer (CRC), but whether H. pylori eradication reduces the risk of CRC is still unknown. Objectives: To compare the incidence of CRC in subjects who had received H. pylori eradication therapy with general population. Design: A population-based retrospective cohort study. Methods: This study included all H. pylori-infected subjects who had received their first course of clarithromycin-containing triple therapy in 2003–2015 in Hong Kong. We compared the observed incidences of CRC in this H. pylori eradicated cohort with the expected incidences in the age- and sex-matched general population. The standardized incidence ratio (SIR) with 95% confidence interval (CI) was computed. Results: Among 96,572 H. pylori-eradicated subjects with a median follow-up of 9.7 years, 1417 (1.5%) developed CRC. Primary analysis showed no significant difference in the observed and expected incidences of CRC (SIR: 1.03, 95% CI: 0.97–1.09). However, when stratified according to the follow-up period, higher incidence of CRC was only observed in the first 5 years after eradication (SIR: 1.47, 95% CI: 1.39–1.55), but it was lower (SIR: 0.85, 95% CI: 0.74–0.99) than general population after 11 years. When stratified by tumor location, the observed incidence was higher for colon (SIR: 1.20, 95% CI: 1.12–1.29) but lower for rectal cancer (SIR: 0.90, 95% CI: 0.81–0.999) among H. pylori-eradicated subjects. Conclusions: H. pylori-infected subjects appeared to have a higher incidence of CRC initially, which declined progressively to a level lower than general population 10 years after H. pylori eradication, particularly for rectal cancer.
Five-Factor Modified Frailty Index as a Predictor of Complications Following Total Ankle Arthroplasty
Authors: Lewis Lauren K. , Jupiter Daniel C. , Panchbhavi Vinod K. , Chen Jie 
Published: May 2023

Introduction Ankle arthritis adversely affects patients’ function and quality of life. Treatment options for end-stage ankle arthritis include total ankle arthroplasty (TAA). A 5-item modified frailty index (mFI-5) has predicted adverse outcomes following multiple orthopaedic procedures; this study evaluated its suitability as a risk-stratification tool in patients undergoing TAA. Methods The National Surgical Quality Improvement Program (NSQIP) database was retrospectively reviewed for patients undergoing TAA between 2011 and 2017. Bivariate and multivariate statistical analyses were performed to investigate frailty as a possible predictor of postoperative complications. Results In total, 1035 patients were identified. When comparing patients with an mFI-5 score of 0 versus ≥2, overall complication rates significantly increased from 5.24% to 19.38%, 30-day readmission rate increased from 0.24% to 3.1%, adverse discharge rate increased from 3.81% to 15.5%, and wound complications increased from 0.24% to 1.55%. After multivariate analysis, mFI-5 score remained significantly associated with patients’ risk of developing any complication (P = .03) and 30-day readmission rate (P = .005). Conclusions Frailty is associated with adverse outcomes following TAA. The mFI-5 can help identify patients who are at an elevated risk of sustaining a complication, allowing for improved decision-making and perioperative care when considering TAA. Levels of Evidence: III, Prognostic
Improving Randomized-Controlled Trials in Foot and Ankle Orthopaedics: The Need to Include Sociodemographic Patient Data
Authors: Martinazzi Brandon J. , Kirchner Gregory J. , Nam Hannah H. , Mansfield Kirsten , Dopke Kelly , Ptasinski Anna , Adeyemo Adeshina , Walley Kempland C. , Aynardi Michael C. 
Published: May 2023

Background The representation of sociodemographic data within randomized-controlled trials (RCT) regarding foot and ankle surgery is undefined. The purpose of this study was to determine the incidence of sociodemographic data being reported in contemporary foot and ankle RCTs. Methods Randomized-controlled trials within the PubMed database from 2016 to 2021 were searched and the full text of 40 articles was reviewed to identify sociodemographic variables reported in the manuscript. Data regarding race, ethnicity, insurance status, income, work status, and education were collected. Results Race was reported in the results in 4 studies (10.0%), ethnicity in 1 (2.5%), insurance status in 0 (0%), income in 1 (2.5%), work status in 3 (7.5%) and education in 2 (5.0%). In any section other than the results, race was reported in 6 studies (15.0%), ethnicity in 1 (2.5%), insurance status in 3 (7.5%), income in 6 (15.0%), work status in 6 (15.0%), and education in 3 (7.5%). There was no difference in sociodemographic data by journal (P = .212), year of publication (P = .216), or outcome study (P = .604). Conclusion The overall rate of sociodemographic data reported in foot and ankle RCTs is low. There was no difference in the reporting of sociodemographic data between journal, year of publication, or outcome study. Level of Evidence: Level II