bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ankilozan Spondilit Hastalarında Hastalık Aktivitesi ile Sistemik İnflamasyon İndeksi ve Trombosit Albumin Oranı Arasındaki İlişki The relationship Between Disease Activity and Systemic Inflammation Index and Platelet Albumin Ratio in Patients with Ankylosing Spondylitis
Authors: TOÇOĞLU Aysel , AKÇAY Emine Ülkü , ERDOĞAN ALTAŞ Ayfer , TUZUN Sabah , DOĞAN Burcu , GÖNÜLLÜ Emel 
Published: August 2023

Amaç: Sistemik İnflamasyon indeksi (SII) ve trombosit albümin oranı (PAR) inflamasyonu değerlendirmek için öne sürülen yeni biyobelirteçlerdir. Çalışmamızda Ankilozan Spondilit (AS) hastalarında hastalık aktivitesi ile SII ve PAR arasındaki ilişkiyi incelemeyi amaçladık.
Yöntem ve Gereçler: AS’li 79 hasta ile 79 sağlıklı kontrol retrospektif olarak değerlendirildi. Katılımcıların demografik, klinik ve laboratuvar verileri poliklinik verileri incelenerek hastane bilgi sistemi üzerinden kayıt edildi. AS grubunda hastalık aktivite durumu Bath Ankilozan Spondilit Hastalık Aktivite İndeksi (BASDAI) skoru hesaplanarak tayin edildi. BASDAI skoru ≥4 olanlar aktif hasta olarak kabul edildi. Aktif hastalığı olan AS hastaları ile remisyonda olan hastalar SII ve PAR açısından karşılaştırıldı.
Bulgular: AS grubunun yaş ortalaması 42,53±6,60, sağlıklı grubun 41,37±10,86 yıldı (p=0,460). AS grubunda 49 (%62,0), sağlıklı grupta 35 (44,3) katılımcı erkekti (p=0,026). AS grubunda sağlıklı gruba göre SII, PAR ve C-reaktif protein albümin oranı (CAR) değerlerinin istatistiksel olarak anlamlı oranda daha yüksek olduğu tespit edildi (sırasıyla p0.05).
Sonuç: AS hastalarında sağlıklı kontroller ile karşılaştırıldığında SII ve PAR değerlerinin artmış olduğu tespit edilirken, beklenenin aksine hastalık aktivitesi ile SII ve PAR değerleri arasında herhangi bir ilişki tespit edilemedi.
SISTEM PAKAR DIAGNOSIS PENYAKIT GINJAL MENGGUNAKAN METODE CERTAINTY FACTOR BERBASIS WEBSITE
Authors: Maulana Muhammad Adrian , Jamaludin Asep , Solehudin Arip , Voutama Apriade 
Published: August 2023

Penyakit ginjal adalah penyakit yang mengganggu fungsi pada organ ginjal. Saat ginjal lemah, penyakit lain bisa menyerang. Tujuan dari penelitian ini adalah untuk menghasilkan suatu aplikasi sistem pakar yang dapat mendiagnosis penyakit ginjal. Aplikasi ini dikembangkan menggunakan bahasa pemrograman PHP dan MySQL sebagai basis data-nya. Penelitian ini menggunakan teknik penelusuran forward chaining sebagai awal pencarian berdasarkan fakta yang muncul sebagai kesimpulan dan metode certainty factor guna menunjukkan presentase tingkat kepercayaan dari kemungkinan penyakit ginjal karena dalam metode ini terdapat suatu nilai kepercayaan (Measure Of Belief) serta nilai ketidakpercayaan (Measure Of Disbelief) pada suatu gejala. Metode pengembangan yang digunakan pada sistem pakar ini adalah metode Expert System Development Life Cycle (ESDLC). Aplikasi sistem pakar diagnosa penyakit ginjal ini juga dapat membantu user dalam mengenali info tentang penyakit ginjal, serta dapat dijadikan solusi alternatif bagi masyarakat untuk melakukan diagnosa dini terhadap gejala-gejala penyakit ginjal yang mereka rasakan.
Күріш қауызы мен лигнин негізіндегі ұялы құрылымды көміртекті тасымалдаушы арқылы зәр қышқылын жою
Authors: Оразбеков A. , Жандосов Ж. , Байменов А. , Азат Сейтхан , Абдусадыков H. , Нургалиев H. , Сабитова А. 
Published: August 2023

Қазіргі күнде биомедицинада ерекше назарға ие болатын перспективті бағыттардың бірі – беттік қабаты ферментпен модифицирленген ұялы құрылымды көміртекті тасымалдағыштардың биокатализ бен гемосорбцияда қолданылуы. Қан құрамында натрий уратының жоғары деңгейі бар гиперурикемиямен ауыратын науқастар подагра, созылмалы бүйрек жеткіліксіздігі және бүйрек тас ауруы сияқты ауруларға бейім.
Зерттеу жұмысында ұялы құрылымды көміртекті тасымалдағыштар 75:25 қатынастағы күріш қауызы мен лигнин қоспасын экструзиялап, ары қарай карбонизациялау, дисиликация және бумен физико-химиялық активациялану жолымен алынған. Сканерлеуші электронды микроскопия, төмен температуралы азотты адсорбциялау әдісі арқылы көміртекті тасымалдағыштардың морфологиясы мен текстуралық сипаттамалары зерттелді: үлгілердің нанокеуектілігі анықталды; BЭT әдісі бойынша меншікті беттік ауданы -1323 м2/г, DFT моделі бойынша кеуектердің жалпы көлемі – 1,053 см3/г құрады.
Уриказа ферментін көміртекті тасымалдағыштардың беттік қабатына 1,5 г көміртекті тасымалдаушыға 1 юнит фермент мөлшерінде байланыстырушы агент мето-п-толуолсульфонат 1-циклогексил-3-(2 морфолиноэтил) карбодиимидтің көмегімен иммобилизациялау жүргізілді.
Натрий уратының субстратының адсорбция немесе катализ арқылы көміртекті тасымалдағыштардың көмегімен шығарылуын анықтау үшін зерттеулер рециркуляциялық жүйеде аргонның инертті ортасында және бөлме температурасында оттегі қатысындағы тотығу ортасында да жүргізілді.
Беттік қабатына 1 юнит уриказа иммобилизденген көміртекті тасымалдағыш концентрациясы 66 мг/л болатын модельді ерітіндіден зәр қышқылын 92 % элиминациялауға қабілетті және ферменттің жуылып кетуі минималды шамада, ал артық мөлшері адам ағзасына түссе, аллергия тудыруы мүмкін. Көміртекті тасымалдаушының масса бірлігіне уриказа юнитінің санын ферментті иммобилизациялау әдісін оңтайландыру арқылы азайтуға болатындығы орнатылды.
Perancangan Desain Maskot Kabupaten Situbondo Dengan Pendekatan Design Thinking
Authors: Abdurrohman Abdurrohman , Aditya Addin , Nurfitri Rina 
Published: August 2023

Perancangan maskot Kabupaten Situbondo sudah melakukan riset terhadap Kabupaten Situbondo, karena banyak masyarakat luar Situbondo tidak tahu tentang Kabupaten Situbondo cuman Kabupaten terdekat saja. penulis mendaptkan beberapa informasi mengenai maskot tapi masyarakat Situbondo banyak tidak tau apa itu maskot dan fungsinya. Maskot digunakan tidak hanya untuk mempromosikan sebuah Kabupaten atau daerah, memberikan edukasi secara persuasif tentang Kabupaten atau daerah tersebut. Metode penelitian yang digunakan pada perancangan ini menggunakan tekhnik pengumpulan data observasi, wawancara, dan kuisioner. Pengumpulan data dilakukan online dengan membagikan kuesioner untuk memperoleh sebuah informasi yang akurat dan hasilnya digunakan untuk mencapai tujuan penelitian.hasil yang didapat berupa karya maskot yang bernama simpan karya ini didapat dari sebuah informasi wawancara dan Ide dari maskot Kabupaten Situbondo ini diambil dari ikon Kabupaten yaitu perahu yang didesain hidup (antrophomorfism) layaknya icon Kabupaten dengan menggunakan topi khas (odheng ) berupa motif kerang yang berasal dari lautan Kabupaten Situbondo dan menciptakan beberapa pose dari karakter maskot Kabupaten SitubondoPenelitian ini bertujuan untuk mengetahui bagaimana menciptakan city branding melalui maskot untuk mempromosikan Kabupaten Situbondo.
PERAN KEPALA SEKOLAH DALAM MENINGKATKAN KOMITMEN DAN KINERJA GURU
Authors: Purwanto Edi , Rindaningsih Ida 
Published: August 2023

Pengkajian ini bertujuan untuk mengetahui peran kepala sekolah dalam meningkatkan komitmen dan kinerja guru. Pengkajian artikel ini disusun dengan menggunakan metode Systematic Literature Review (SLR). Di Indonesia, tinjauan literatur sistematis adalah metode tinjauan literatur yang mengidentifikasi, meninjau, mengevaluasi, dan menginterpretasikan semua penelitian yang ada. Kepala sekolah berfungsi sebagai leader dan manajer di sekolah yang mempunyai peran penting dalam mewujudkan visi dan misi sekolah. Komitmen guru merupakan kekuatan batin yang yang datang dari dalam hati seseorang guru dan kekuatan dari luar itu sendiri tentang tugasnya yang dapat memberi pengaruh besar terhadap sikap berupa tanggung jawab dan sikap responsip dan inovatif terhadap perkembangan ilmu pengetahuan dan teknologi. Gaya kepemimpinan yang diterapkan oleh kepala sekolah akan mempengaruhi komitmen dan kinerja para guru akan menjadi lebih baik. Kinerja guru dapat ditingkatkan ketika para guru mempunyai motivasi kerja yang lebih baik. Berdasarkan hasil analisis, dengan pendekatan-pendekatan kepala sekolah kepada guru dapat berpengaruh meningkatkan kinerja guru.
Analisis Profitabilitas dan Tingkat Kesejahteraan Petani Bawang Merah di Kecamatan Mijen Kabupaten Demak
Authors: Putri utami Inayah Rahmawati , Roessali Wiludjeng , Gayatri Siwi 
Published: August 2023

Komoditas bawang merah memiliki nilai ekonomis tinggi dan banyak digunakan sebagai bahan utama bumbu dasar masakan di Indonesia, selain itu dimanfaatkan sebagai bahan obat-obatan. Kabupaten Demak merupakan salah satu sentra produksi bawang merah di Jawa Tengah. Kontribusi produksi bawang merah Kabupaten Demak terhadap produksi provinsi sebesar 13 %. Usaha tani bawang merah di Indonesia masih menghadapi banyak kendala, tidak terkecuali di Kabupaten Demak. Kendala usahatani tersebut di antaranya ancaman konversi lahan, harga bibit berkualitas mahal dan belum optimalnya penggunaan input produksi. Tujuan dari penelitian ini adalah menganalisis pendapatan dan profitabilitas usahatani bawang merah, pengeluaran rumah tangga petani bawang merah di Kecamatan Mijen Kabupaten Demak dan Tingkat kesejahteraan rumah tangga petani bawang merah di Kecamatan Mijen Kabupaten Demak. Sampel yang diambil dalam penelitian ini adalah petani bawang merah sebanyak 96 responden yang ditentukan menggunakan rumus slovin dengan tingkat eror 10%. Berdasarkan hasil analisis didapat pendapatan petani bawang merah di Kecamatan Mijen Kabupaten Demak sebesar Rp 119.188.411,00 dengan rata – rata luas lahan petani 7600 m2. Nilai profitabilitas sebesar sebesar 169,67% dimana tingkat bunga deposito Bank BRI saat penelitian ini berlangsung yaitu 3,75% artinya usahatani bawang merah di Kecamatan Mijen layak untuk dijalankan. Total pengeluaran rumah tangga petani bawang merah di Kecamatan yaitu Rp 88.039.262/MT. Pengeluaran tersebut terdiri atas pengeluaran usahatani sebesar Rp 70.117.256 dan pengeluaran non usahatani Rp 17.922.006. Nilai tukar pendapatan rumah tangga petani bawang merah yaitu sebesar 1,48 yang mana nilai tersebut lebih besar dari 1 artinya tingkat kesejahteraan petani sudah masuk kedalam golongan sejahtera.
A Solar PV Model Parameter Estimation Based on the Enhanced Self-Organization Maps
Authors: El Marghichi Mouncef 
Published: August 2023

Solar photovoltaic (PV) is a commonly utilized renewable energy source, with PV cells often being modeled as electric circuits. The identification of suitable circuit model parameters for PV cells is vital for performance evaluation, efficiency calculations, and the implementation of maximum power point tracking in solar PV systems. However, modeling the solar PV system is a nonlinear problem that requires an efficient algorithm. In this paper, we employ the enhanced self-organization maps (EASOM) to efficiently reduce the search space for parameter estimation in solar PV models. Our algorithm trains the SOM network on a subset of solutions, identifies the top solution's neural unit, generates a population of potential solutions, and selects the best candidate using a cost function, which represents the best PV model parameters obtained. The performance of EASOM is verified by extracting the parameters of the single diode (SDM) and double diode (DDM) models for the STM6-40/36 PV module. EASOM outperformed state-of-the-art algorithms with the lowest RMSE and MSE values of 8.3 mA and 6.87e-05 and achieved the lowest maximum error values of 27.37 mA and 20.52 mA, as well as low power error of 66.04 mW and 62.8 mW for SDM and DDM models.
Chloroquine Induced Retinal Toxicity- A Case Report
Authors: Nahar Nazmun , Barua Palash , Shahnaz Kaniz Ahmed 
Published: August 2023

Chloroquine (CQ) and hydroxychloroquine (HCQ) is used increasingly in the management of variety of autoimmune disorders with well-established role in dermatology, rheumatology, and oncology. Retinopathy in the form of maculopathy occurs due to long term use of CQ or HCQ in large dose, have been associated with irreversible visual loss. A middle aged diabetic patient had been complaining of profound dimness of vision following uncomplicated cataract surgery on both eyes. She had a very good vision (6/6) in both eyes which reduced to 6/60 and 5/60 in right and left eye respectively. Colour fundus photography (CFP), Visual field analysis (VFA), Optical coherence tomography (OCT) and Fundus fluorescein angiography (FFA) revealed the changes consistent with “bulls’ eye maculopathy”. Treatment was unsatisfactory with antioxidant and neuro vitamin.
J. Natl. Inst. Ophthalmol. 2022; 5(2):42-44
Association of Serum IgE with Keratoconus
Authors: Raihan Mohammad Hussain , Khan Md Kamrul Hasan , Kajmina Natasha , Rahman Md Mahbubur , Rashid Md Shoeb Ur , Shuchi Tarzeen khadiza 
Published: August 2023

Purpose: Keratoconus is an ectatic corneal disease characterized by regional thinning and protrusion that leads to irregular astigmatism and, ultimately, substantial vision impairment. The aim of this study was to see if there was a link between serum IgE levels and keratoconus.
Methods: At the Combined Military Hospital Dhaka, a prospective observational study was conducted in the general Eye OPD and Cornea clinic. The study involved 60 participants who were divided into 2 groups. Thirty people with keratoconus were assigned to Group A, while 30 healthy people were assigned to Group B. All 60 patients had their serum IgE levels checked.
Results: The mean age of the study subjects in Group A and group B were 19.60±5.28 (SD), and 20.23±5.62 (SD) respectively; 13 were male and 17 were female in Group-A, and 10 were male and 20 were female in Group-B. Serum IgE was 243.183±143.059 (SD) in group-A and 86.067±77.065 (SD) in group-B. There was a significant rise in serum IgE in Group-A (p value <0.0001).
Conclusion: Elevated serum IgE levels are strongly associated with keratoconus. Measuring serum IgE could be an important parameter in the management of Keratoconus.
J. Natl. Inst. Ophthalmol. 2022; 5(2):21-24
Analisis Potensi Daya Pada Pembangkit Unit 7 PLTA Tes
Authors: Agustian Firmansyah Adam Permana , Helmizar  
Published: August 2023

Currently the need for electrical energy is increasing both for industrial and household needs, but until now a lot of electrical energy has been replaced by non-renewable resources (coal), which will run out if it continues to be used. Tes Hydroelectric Power Plant is one of the electrical energy generators that can be renewable. Among the several generating units in Tes Hydroelectric Power Plant, Tes’s hydroelectric power plant unit 7 is the most recent, having been inaugurated for the first time in 2014. The power potential that can be projected from this hydroelectric power plant unit 7 still needs to be looked at further. Therefore, this study aims to analyze the potential for electric power from the Tes’s hydroelectric power plant unit 7 from 01 July 2022 to 03 July 2022.
In making observations about the analysis of the power potential at the Tes’s hydroelectric power plant unit 7, several methods are used. Such as observation of data for 3 days of operation from 01 July 2022 to 03 July 2022, literature study and several interview methods with field consultants. The value of the air discharge obtained from the use of air volume per day at the Tes’s hydroelectric power plant unit 7. On three days of observation, the Tes’s hydroelectric power plant unit 7 were able to produce the highest electrical energy on 03 July 2022, namely 100,722 kWh and the lowest was 99,808 kWh on 02 July 2022. In three days, the electric power that paid for the Tes’s hydroelectric power plant unit 7 reached 4173, 40 kW. The Tes’s hydroelectric power plant unit 7 can generate a daily net income of Rp. 105,689,588, - with a perkWh price of Rp. 1300, - and reduced by the basic cost of Rp. 244.81, -, from the sale of electrical energy.
Vibrational Spectra of the thioglycolate complexes of Zn(II) and Cd(II), structure and natural bond orbitals
Authors: Pinheiro Renata Batista dos Santos , Costa Junior Anilton Coelho da , Téllez Zepeda Claudio Andrés , Ricarte Kátia Magaly Pires , Mondragón Maria Antonieta , Cabral Otávio Versiane , Téllez Soto Claudio Alberto 
Published: August 2023

The objective of this research was to characterize the vibrational spectrum of the Zn(II) and Cd(II) thioglycolate complexes, as well as their structures, vibrational analysis and the natural orbitals of bonds, through the infrared spectrum with Fourier transform (FT -IR) and Raman. The thioglycolate complexes of Zn(II) and Cd(II) were synthesized following procedures given by the graphical method, and structural analysis was performed through a theoretical-experimental method using both, the hybrid RHF/MP2:STO-3G and the experimental FT-IR and FT-Raman spectra. Calculations were performed on the optimized structure and harmonic vibrational wavenumbers for both complexes were obtained. Second derivative of the vibrational spectra and deconvolution analysis were also performed. The infrared and Raman spectra show many combination and overtone bands in both cases. Calculated and experimental spectra confirmed the structural hypothesis considering two ATG (thioglycolic acid) with two water molecules in the coordination sphere of the central atoms. The natural bond orbital analysis (NBO) was also carried out to study the Zn(II) and Cd(II) hybridization leading to a pseudo-octahedral geometry for both complexes.
IMPLEMENTATION OF STRING SIMILARITY ALGORITHM IN PUBLIC COMPLAINT APPLICATIONS TO MINIMIZE SIMILAR COMPLAINTS
Authors: Gunawan Dedi , Aditya Ahimsa Prana 
Published: August 2023

Presently, the complaining service in Kartasura local government relies on manual recording where people must come to the government office, write their complaints and submit them to the office staff. This situation causes inefficiency since people have to travel from their places to the local government office. Moreover, the manual recording makes the complaints cannot be managed properly since the same complaints can be submitted more than one time. Additionally, it also causes some confusion to the government staff since they need to carefully check whether it has been submitted previously and approve the complaints accordingly. To solve the issue, a web-based application complaint system is developed to reduce the number of the same complaints from the citizen as well as to help staff manage the complaints data. The Jaro-Winkler String Similarity algorithm is adopted to check the similarity of newly submitted complaints with existing complaints data. The algorithm detects similarities of newly submitted complaints by determining the level of string equality to the existing complaints. Experimental results using one month period of complaints data in December 2022 show that the application is able to detect the similarity between the newly submitted complaints to the existing complaints. As the value of similarity threshold is higher, the number of rejected complaints also increases. Meanwhile, the test results of the system using the System Usability Scale Score obtained an average value of 76.5, which means the system is included in the Acceptable category and can be used for daily activity.
Characterization ofantifungal properties of lipopeptide-producing Bacillus velezensis strains and their proteome-based response to the phytopathogens, Diaporthe spp
Authors: Akintayo Stephen Olusanmi , Hosseini Behnoush , Vahidinasab Maliheh , Messmer Marc , Pfannstiel Jens , Bertsche Ute , Hubel Philipp , Henkel Marius , Hausmann Rudolf , Voegele Ralf T. , Lilge Lars 
Published: August 2023

Introduction:B. velezensis strains are of interest in agricultural applications due to their beneficial interactions with plants, notable through their antimicrobial activity. The biocontrol ability of two new lipopeptides-producing B. velezensis strains ES1-02 and EFSO2-04, against fungal phytopathogens of Diaporthe spp., was evaluated and compared with reference strains QST713 and FZB42. All strains were found to be effective against the plant pathogens, with the new strains showing comparable antifungal activity to QST713 and slightly lower activity than FZB42.Methods: Lipopeptides and their isoforms were identified by high-performance thin-layer chromatography (HPTLC) and mass spectrometric measurements. The associated antifungal influences were determined in direct in vitro antagonistic dual culture assays, and the inhibitory growth effects on Diaporthe spp. as representatives of phytopathogenic fungi were determined. The effects on bacterial physiology of selected B. velezensis strains were analyzed by mass spectrometric proteomic analyses using nano-LC-MS/MS.Results and Discussion: Lipopeptide production analysis revealed that all strains produced surfactin, and one lipopeptide of the iturin family, including bacillomycin L by ES1-02 and EFSO2-04, while QST713 and FZB42 produced iturin A and bacillomycin D, respectively. Fengycin production was however only detected in the reference strains. As a result of co-incubation of strain ES1-02 with the antagonistic phytopathogen D. longicolla, an increase in surfactin production of up to 10-fold was observed, making stress induction due to competitors an attractive strategy for surfactin bioproduction. An associated global proteome analysis showed a more detailed overview about the adaptation and response mechanisms of B. velezensis, including an increased abundance of proteins associated with the biosynthesis of antimicrobial compounds. Furthermore, higher abundance was determined for proteins associated with oxidative, nitrosative, and general stress response. In contrast, proteins involved in phosphate uptake, amino acid transport, and translation were decreased in abundance. Altogether, this study provides new insights into the physiological adaptation of lipopeptide-producing B. velezensis strains, which show the potential for use as biocontrol agents with respect to phytopathogenic fungi.
Preliminary feasibility study using a solution of synthetic enzymes to replace the natural enzymes in polyhemoglobin-catalase-superoxide dismutase-carbonic anhydrase: effect on warm ischemic hepatocyte cell culture
Authors: Hoq M. , Chang T. M. S. 
Published: August 2023

This is a study on a simple solution of chemically prepared small chemical molecules of synthetic enzymes: catalase, superoxide dismutase, and carbonic anhydrase (CAT, SOD, and CA). We carried out a study to see if these synthetic enzymes can replace the natural enzymes (CAT, SOD, and CA) and avoid the need for the complicated cross-linking of natural enzymes to PolyHb to form PolyHb-CAT-SOD-CA. We compared the effect a solution of these three synthetic enzymes has on the viability of warm-ischemic hepatocytes that were exposed to nitrogen for 1 h at 37°C. PolyHb significantly increased the viability. The three synthetic enzymes themselves also significantly increased the viability. The use of both PolyHb and the three synthetic enzymes resulted in an additive effect in the recovery of viability. Increasing the concentration of the synthetic enzymes resulted in further increase in the effect due to the synthetic enzymes.Implications: In addition to PolyHb, there are a number of other HBOC oxygen carriers. However, only Biopure’s HBOC product has received regulatory approval, but only in Russia and South Africa. None of the HBOCs has received regulatory approval by other countries. If regulatory agencies require HBOCs to have antioxidant or CO2 transport properties, all that is needed is to add or inject the solution of synthetic enzymes as a separate component.