bluuebunny/crossref_metadata_2025_split huggingface dataset:
ONSHORE-OFFSHORE TRENDS IN THE TEMPORAL RESOLUTION OF MOLLUSCAN DEATH ASSEMBLAGES: HOW AGE-FREQUENCY DISTRIBUTIONS REVEAL QUATERNARY SEA-LEVEL HISTORY
Authors: DO NASCIMENTO RITTER MATIAS , ERTHAL FERNANDO , KOSNIK MATTHEW A. , KOWALEWSKI MICHAŁ , COIMBRA JOÃO CARLOS , CARON FELIPE , KAUFMAN DARRELL S. 
Published: April 2023

AbstractSurficial shell accumulations from shallow marine settings are typically averaged over centennial-to-millennial time scales and dominated by specimens that died in the most recent centuries, resulting in strongly right-skewed age-frequency distributions (AFDs). However, AFDs from modern offshore settings (outer shelf and uppermost continental slope) still need to be explored. Using individually dated shells (14C-calibrated amino acid racemization), we compared AFDs along an onshore-offshore gradient across the southern Brazilian shelf, with sites ranging from the inner shelf, shallow-water (&lt; 40 m) to offshore, deep-water (&gt; 100 m) settings. The duration of time averaging is slightly higher in deeper water environments, and the AFD shapes change along the depositional profile. The inner shelf AFDs are strongly right-skewed due to the dominance of shells from the most recent millennia (median age range: 0–3 ka). In contrast, on the outer shelf and the uppermost continental slope, AFDs are symmetrical to left-skewed and dominated by specimens that died following the Last Glacial Maximum (median age range: 15–18 ka). The onshore-offshore changes in the observed properties of AFDs—increased median age and decreased skewness, but only slightly increased temporal mixing—likely reflect changes in sea level and concurrent water depth-related changes in biological productivity. These results suggest that on a passive continental margin subject to post-glacial sea-level changes, the magnitude of time-averaging of shell assemblages is less variable along the depositional profile than shell assemblage ages and the shapes of AFDs.
Evaluation of the Effect of Polishing Methods on Surface Roughness in Primary Molars by Atomic Force Microscopy
Authors: Duman Burcu , doğan Salih 
Published: April 2023

Abstract
Recurrent tooth discoloration due to the increase in roughness after polishing is a concern for patients and dentists. This study evaluated the surface roughness of primary molars after different polishing methods through atomic force microscopy (AFM). A total of 88 primary teeth were randomly assigned to 4 groups, 22 teeth in each group. Before polishing, roughness measurements and visualizations were performed with AFM. The teeth were polished with four different polishing pastes (Imipomza®, Septodent Détartrine®, Kerr Cleanic®, Shofu Mersaage Regular ®) in line with the manufacturer's recommendations. After polishing, average roughness (Ra) values, which express the surface roughness of the re-scanned teeth. The Ra scores were then statistically analysed. In the groups; while there was no significant difference in terms of roughness values ​​(Ra) within the group (p > 0.05), a statistically significant reduction in roughness (Ra) was observed on the sample surfaces after polishing in all groups compared to the baseline (p < 0.05). All polishing methods used in the treatment of primary tooth discoloration can reduce the plaque formation and thus the amount of recoloring by reducing the surface roughness at a similar level.The traditional polishing method (pumice polishing brush), which is more economical and easy to reach, can continue to be used instead of existing polishing pastes in removing discoloration on primary teeth.
Isolated long thoracic nerve palsy following COVID-19 vaccine: a case report.
Authors: Cutsem Gilles Van , Bolyn Serge 
Published: April 2023

Abstract
Introduction: We report an adult man who developed an isolated long thoracic nerve palsy three days following vaccination against COVID-19. To the best of our knowledge this is the first well-documented case of this association.
Case presentation: A 46-year-old white man developed back pain, followed by pain in the right axilla and scapular region, clumsiness of the right arm and unusual position of his shoulder blade, three days after receiving a second dose of the Pfizer-BioNTech COVID-19 vaccine. When he consulted a neurologist six months later, the pain had subsided, but the other symptoms persisted despite physiotherapy. Main clinical findings were right scapular winging and marked amyotrophy of the serratus anterior, with preservation of the other muscles of the shoulder and scapula. Nerve conduction studies yielded a low amplitude with a slightly prolonged latency of the right long thoracic nerve. Needle electromyography showed decreased compound motor action potentials on the right and was normal on the left.
Main diagnosis and interventions: A diagnosis of post-immunisation long thoracic neuritis was made. The patient was treated with physiotherapy.
Conclusions: Clinicians should be aware of the possibility of neuritis of any nerve after COVID-19 vaccination.
Trauma-informed mental health and/or substance use prevention programs for young people: protocol for a mixed-methods systematic review
Authors: Peters Leslie , Newton Nicola , Perry Yael , Grummitt Lucinda , Baams Laura , Barrett Emma 
Published: April 2023

Abstract
Background: Mental ill-health and substance use bear substantial burden and harms on young people, and often arise from co-occurring and compounding risk factors, such as traumatic stress. Trauma-informed prevention of mental ill-health and substance use demonstrates significant promise in reducing this burden. A systematic literature review is required to identify and summarise the effectiveness, feasibility, acceptability, and design principles underpinning existing trauma-informed mental ill-health and/or substance use prevention programs for young people aged 12-24 years.
Methods: MEDLINE, Embase, CINAHL, PsychINFO and Cochrane Library will be searched from 2012 through September 2022 as will Informit, Analysis and Policy Observatory (APO), and Google (Advanced Search) for relevant grey/unpublished literature. Reference lists of included articles will be citation chained. Title and abstracts will be screened and two reviewers will review articles full-text. One reviewer will extract data from eligible articles using a piloted data extraction form, and 20% of data will be verified by a second reviewer. Risk of bias will be assessed using the Cochrane risk-of-bias tool for randomised trials (RoB 2), Risk of Bias in Non-randomised Studies of Interventions (ROBINS-I), and Confidence in the Evidence from Reviews of Qualitative Research (GRADE CERQual) tool, depending on the study type. Characteristics of existing trauma-informed mental ill-health and/or substance use prevention programs for young people will be summarised narratively. Effectiveness, feasibility, and acceptability will be qualitatively described and summarised, with proportions and effect sizes quantitatively synthesised, where possible.
Discussion: Trauma-informed approaches to prevention demonstrate significant promise yet to date no study has systematically summarised and synthesised the available literature. To fill this gap, the present review will systematically identify and summarise the effectiveness, feasibility, acceptability, and design principles underpinning existing trauma-informed mental health and/or substance use prevention programs for young people aged 12-24. This review will inform development, adaptation, evaluation and implementation of future traumainformed mental ill-health and substance use prevention programs for young people. Findings will inform critical efforts to interrupt and prevent already elevated trajectories of mental ill-health, substance use and related harms among those young people exposed to adversity.
Systematic review registration This review protocol has been submitted to PROSPERO (CRD42022353883).
Guided self-help for anxiety among Huntington’s disease gene expansion carriers (GUIDE-HD) compared to treatment as usual: a randomised controlled feasibility trial
Authors: Dale Maria , Eccles Fiona J R , Melvin Katie , Khan Zaynah , Jones Lee , Zarotti Nicolò , Kiani Reza , Johnson Jenny , Wells Robert , Simpson Jane 
Published: April 2023

Abstract

Background: Huntington’s disease (HD) is an adult-onset genetic neurodegenerative condition, involving cognitive decline, motor impairments and emotional difficulties. Anxiety affects up to 71% of HD gene expansion carriers (i.e., those with the version of the gene that causes HD) and can negatively affect quality of life, worsen other HD symptoms, and increase suicide risk. Therefore, helping people with their anxiety should be a clinical priority. A significant evidence base now exists for low-cost talking therapies for anxiety, such as guided self-help, and with people with other neurodegenerative diseases (e.g., Parkinson’s disease). However, this type of intervention has not been specifically assessed for HD gene expansion carriers.
Methods: This protocol describes an exploratory randomised controlled feasibility study of a psychological intervention for anxiety. The 10 session guided self-help intervention is based on a blend of second and third wave cognitive behavioural models of anxiety and adapted to meet the specific needs of an HD population. This study will compare guided self-help (GSH) with treatment as usual (TAU), with 15 HD gene expansion carriers randomly allocated to each group. Participants will be recruited across the East Midlands region in the UK. Quantitative data will be collected pre intervention, immediately post intervention, three-month post intervention and six-month post intervention; qualitative data will be collected at one month post intervention. The data will be analysed to assess whether the current intervention and study design meets pre-determined criteria that would indicate feasibility to progress to a larger randomised controlled trial. HD carers will also be invited for interview within 1-month post-intervention and these data will be analysed qualitatively.
Discussion
Given the lack of evidenced interventions to date to support the wellbeing of people with the expanded Huntington’s gene, this study will assess the feasibility of progressing this particular intervention to a full trial. To try and increase the acceptability of the intervention, a number of stakeholders, including those affected by HD and in caring roles, have been fundamental to the creation of the intervention (e.g., therapy manual, planned therapy process) to date.
Trial registration
Trial ID: ISRCTN47330596
Date registered: 28/09/2022
Link: https://www.isrctn.com/ISRCTN47330596
Impact on sexual functioning: total versus subtotal hysterectomy
Authors: Ferhi Mohamed , Abdeljabbar Ameni , Jaballah Fares , Jihenne Mannai , Bouzid Riadh , Nadia Marwen 
Published: April 2023

Abstract
Background
As with any surgical procedure, several complications can arise during the hysterectomy. A complication that has been documented in the literature is a detrimental effect on sexual performance. On the other hand, this surgical procedure resulted in better sexual functioning according to other studies. These findings made the topic a matter of controversy which inspired us to carry out this study.
Objective The aim of this study was to evaluate and compare sexual functioning in women undergoing total (TH) and subtotal hysterectomy (STH).
Methodology A longitudinal, prospective and comparative study in women undergoing hysterectomy for benign diseases (N=60). Sexual dysfunction was evaluated by means of the Arizona Sexual Experiences Scale (ASEX) and Female Sexual Function Index (FSFI) before the hysterectomy and after 6 months. The sociodemographic and clinical parameters were examined using the patient's medical records.
Results Following surgery, significant improvement in sexual functioning according to both scales. In fact, the mean total score of the ASEX scale went from 25.14 to 21.15 and from 11,99 to 19,31 for the FSFI. The average time to resume sexuality postoperatively was 50 days. No significant difference was found in these results between total and subtotal hysterectomy.
Conclusion Hysterectomy, whether total or subtotal, has a positive impact on the overall sexual satisfaction of the patients especially in those with an impaired sexuality before surgery. There were no statistically significant differences in sexual function between the two groups TH versus STH. Therefore, cervix preservation for the purpose of improving overall sexual satisfaction cannot be recommended.
The role of economic freedom in achieving the environmental sustainability for the highest economic freedom countries: testing the environmental Kuznets curve hypothesis
Authors: Bektur Cisem 
Published: April 2023

AbstractIn the study, the relationship between ecological footprint, economic freedom, renewable energy consumption and economic growth is analysed under the scope of environmental Kuznets curve (EKC) hypothesis. Here, fifteen countries with the highest economic freedom for the period 1996–2018 are examined i.e., Australia, Canada, Denmark, Estonia, Finland, Germany, Latvia, Lithuania, Luxembourg, Netherlands, Norway, Singapore, South Korea, Sweden, and Switzerland. The long-term relationship between the variables is examined using the panel cointegration test. According to the test results, it has been observed that the variables in the EKC model act together in the long run. According to the long term estimation results, it is seen that economic freedom decreases the ecological footprint, namely environmental degradation, in Canada, while it increases in Estonia. Furthermore, it is concluded that renewable energy reduces the ecological footprint in Australia, Denmark, Luxembourg, Norway, Singapore, and Switzerland. Nevertheless, it has been determined that the EKC hypothesis is valid for Canada, Denmark, and Singapore, but not for other countries.
Mediating effects of DNA methylation on the association of sleep quality with infertility among women of childbearing age
Authors: Tang Ying , Gan Hong , Wang Baolin , Wang Xiaorui , Li Mengdie , Yang Qianhui , Geng Menglong , Zhu Peng , Shao Shanshan , Tao Fangbiao 
Published: April 2023

Abstract
Background
To investigate the association between sleep quality and infertility in Chinese females and to explore the mediating effects of DNA methylation.
Methods
This study was based on the Reproductive Health of Childbearing Couples - Anhui Cohort (RHCC-AC) study in China. We used the Illumina Infinium Human Methylation 850k BeadChip to detect changes in DNA methylation in peripheral blood samples. Here, we compared the relationship between female sleep characteristics and infertility in females with anovulatory infertility (n = 43) and healthy female controls (n = 43). A total of 753 354 CpG sites were included in the final analysis. We identified differentially methylated sites between cases and controls using the R package ChAMP. The R package “mediation” Bayesian estimation method was used to investigate the mediation effect between sleep quality and infertility among women.
Results
Of the 753 354 probes on the EPIC Beadchips analyzed, a total of 763 differentially methylated CpG sites corresponding to 476 genes were identified, including 540 hypermethylated sites and 223 hypomethylated sites. Difficulty falling asleep was a risk factor for infertility in females, and a causal mediation effect of DNA methylation sites was found (cg07675898, cg08298632 and cg15500907).
Conclusions
These results suggest that DNA methylation sites play a significant role between difficulty falling asleep and infertility in women, and a total of three methylation sites (cg07675898, cg08298632 and cg15500907) were found to be mediating variables. With the help of causal mediation analysis, the mediation effect of DNA methylation between difficulty falling asleep and female infertility provided new clues for the prevention and treatment of female infertility.
A time-series analysis of short-term ambient ozone exposure and hospitalizations from acute myocardial infarction in Henan, China
Authors: Wei Yulong , Fei Lin , Wang Yongbin , Zhang Min , Chen Zhigang , Guo Huige , Ge Shiqi , Zhu Sen , Dong Pingshuan , Yang Kan , Xie Na , Zhao Guoan 
Published: April 2023

Abstract
Epidemiological studies in recent years have identified an association between exposure to air pollutants and acute myocardial infarction (AMI); however, the association between short-term ozone (O3) exposure and AMI hospitalization remains unclear, particularly in developing countries. Therefore, this study collected information on 24,489 AMI patients, including daily air pollutant and meteorological data in Henan, China, between 2016 and 2021. A distributed lagged nonlinear model combined with a Poisson regression model was used to estimate the nonlinear lagged effect of O3 on AMI hospitalizations. We also quantified the effects of O3 on the number of AMI hospitalizations, hospitalization days, and hospitalization costs. The results showed that single- and dual-pollution models of O3 at lag0, lag1, and lag (01–07) were risk factors for AMI hospitalizations, with the most significant effect at lag03 (RR=1.132, 95% CI:1.083–1.182). Further studies showed that males, younger people (15–64 years), warm seasons, and long sunshine duration were more susceptible to O3. Hospitalizations attributable to O3 during the study period accounted for 11.66% of the total hospitalizations, corresponding to 2,856 patients, 33,492 hospital days, and 90 million RMB. Maintaining O3 at 10–130 µg/m3 can prevent hundreds of AMI hospitalizations and save millions of RMB per year in Henan, China. In conclusion, we found that short-term exposure to O3 was significantly associated with an increased risk of hospitalization for AMI in Henan, China and that further reductions in ambient O3 levels may have substantial health and economic benefits for patients and local healthcare facilities.
Inflow-Velocity and Rotational Effects on Revolving and Translating Wings
Authors: Paulson James , Jardin Thierry , Buchholz James 
Published: April 2023

Abstract
An aspect ratio 9.5 rectangular wing is articulated in revolving and translating motions at a 45-degree angle of incidence and Reynolds number Re = O(300). The effects of rotational (Coriolis and centripetal) accelerations and relative inflow velocity profile are independently investigated. For the range of displacements studied (180 deg. rotation and corresponding translational displacement) a stably attached leading-edge vortex (LEV) is observed when rotational accelerations and/or a linearly-varying inflow velocity profile is present; however, the inflow velocity profile has a stronger effect on stability of the LEV. LEV vorticity magnitude and lift are significantly augmented when both factors are included (i.e. the full revolving wing case). Vorticity transport analyses are conducted in a planar control region two chords from the axis of rotation, where three-dimensional vorticity transport is shown to be important in mitigating LEV growth, and at an equivalent distance from the wing root in the translating case. The fully revolving wing case exhibits a substantially larger leading-edge shear-layer vorticity flux than the other cases, whereas Coriolis tilting makes little contribution to regulation of LEV strength. A correlation is found between the spanwise convective flux and tilting flux contributions in all cases. Decomposition of the spanwise convective flux term demonstrates that the two phenomena are kinematically linked and yields a significantly simplified vorticity transport equation with a single term consolidating the three-dimensional transport fluxes, thus providing new physical interpretation of vorticity transport in leading-edge vortices.
Exploring available landslide inventories for susceptibility analysis in Gipuzkoa province (Spain)
Authors: Bornaetxea Txomin , Remondo Juan , Bonachea Jaime , Valenzuela Pablo 
Published: April 2023

Abstract
As in many landslide-prone areas of the world, landslides are recurrent in the Gipuzkoa province (northern Spain) and commonly cause damage to communication infrastructure such as roads and railways. This geomorphological process also threatens buildings and human beings, albeit in a lesser level. Despite the individual efforts by different institutions and academic research groups, basic and crucial information about historic and ancient landslides occurred in this territory—i.e., landslide inventories—is incomplete or unevenly distributed throughout the province. The aim of this work is to present the state of the art on landslide information through the description of the existing landslide inventories conducted in Gipuzkoa to date. Among the collected information, 5 landslide inventories are in digital format and 11 on paper maps, spanning the period 1991 to 2018. We have compared the digital databases using different strategies to assess their differences and provide some recommendations, specific for Gipuzkoa, to improve the quality of landslide information currently available, to avoid duplicate efforts in data collection and further the understanding of landslide occurrences at regional scale.
Detection of oxytetracycline in milk using a novel carbon dots-based fluorescence probe via facile pyrolysis synthesis
Authors: Yang Zhenhua , Yang Xintong , Zhang Yuexia , Fan Xiaopeng , Cao Yujuan , Li Zhongping , Dong Chuan 
Published: April 2023

Abstract
Amphiphilic blue-fluorescence carbon dots (B-CDs) were synthesized via pyrolysis method with citric acid and oleamine as precursors. B-CDs are monodispersed in ethanol, toluene and ultrapure water with the average particle sizes of 3.33 nm, 2.05 nm and 4.12 nm, respectively. The maximum excitation and emission wavelengths of these B-CDs are located at 370 and 459 nm, respectively. The B-CDs have good optical properties with excellent photostability. The fluorescence quantum yield (QY) of the as-prepared CDs is as high as 30.17%. The fluorescence of B-CDs is quenched because of static quenching by oxytetracycline. A high selective and sensitive fluorescence probe for detecting oxytetracycline was constructed with a linear range of 1.52-27.60 µg/mL and the detection limit of 0.33 µg/mL. The B-CDs-based fluorescence probe can be applied to analyze oxytetracycline in milk; the recoveries and relative standard are satisfactory. Furthermore, the B-CDs were exploited for imaging of SH-SY5Y cells. The results demonstrated that as-synthesized CDs can serve as a cellular imaging reagent owing to rematkable bioimaging performance. This work provides a new strategy for the detection of oxytetracycline in food.
‘More stressful than cancer’: Treatment Experiences Lived During Hurricane Maria among Breast and Colorectal Cancer Patients in Puerto Rico
Authors: Colón-López Vivian , Sánchez-Cabrera Yara , Soto-Salgado Marievelisse , Ortiz-Ortiz Karen J. , Quast Troy , Fernández María E. 
Published: April 2023

Abstract
Background: This study explored experiences in cancer care and disruption after Hurricanes Irma and Maria’s aftermath in Puerto Rico (PR).
Methods: A total of three focus groups were conducted among breast and colorectal cancer patients diagnosed six months before the disaster.
Results: The most prevalent themes were (a) barriers related to their cancer treatment, (b) facilitators related to their cancer treatment, and (c) treatment experiences during the hurricane. Participants discussed struggles regarding their experience with treatment and access to care during and after Hurricanes Irma and Maria and how household limitations due to lack of electricity and water deter their intention to continue their treatment. Moreover, stressors directly linked with the disaster were the most challenging to cope with.
Conclusions: Our study identifies the hardships experienced by cancer patients living during a disaster. Similarly, our study highlights the impending need to address in future emergency plans the individual and system needs of cancer patients in active treatment to minimize the delay in continuing cancer care.