bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Penerapan Model Pembelajaran Penemuan (Discovery Learning) Berbantuan Handout Terhadap Kemampuan Berpikir Kreatif dan Hasil Belajar Kimia Siswa
Authors: Saputri Ika Kurnia Rara , Muntari Muntari 
Published: January 2025

Penelitian ini bertujuan untuk mengetahui pengaruh dari penerapan model pembelajaran penemuan (discovery learning) berbantuan handout terhadap kemampuan berpikir kreatif dan hasil belajar kimia siswa kelas X IPA SMA Negeri 4 Mataram. Jenis penelitian yang digunakan adalah eksperimen semu dengan desain penelitian Pretest-Posttest Control Group Design. Populasi dalam penelitian ini adalah siswa kelas X IPA SMA Negeri 4 Mataram yang berjumlah 143 orang dan tersebar dalam 4 kelas IPA. Teknik pengambilan sampel yang digunakan yaitu purposive sampling. Sampel pada penelitian ini yaitu kelas X IPA 1 sebagai kelas eksperimen dan X IPA 2 sebagai kelas kontrol. Pada kelas eksperimen diberi perlakuan dengan menggunakan model pembelajaran penemuan (discovery learning) berbantuan handout, sedangkan kelas kontrol diberi perlakukan dengan menggunakan model pembelajaran konvensional. Instrumen yang digunakan berupa tes tertulis berbantuk uraian. Uji hipotesis pada penelitian ini menggunakan uji-t pada analisis kemampuan berpikir kreatif dengan hasil uji statistik pada taraf signifikan 5% menunjukkan thitung (4,850) > ttabel (1,669) yang berarti H0 ditolak dan Ha diterima dan uji Mann Whitney U-test pada analisis hasil belajar kimia dengan hasil uji statistik pada taraf signifikan 5% menunjukkan Zhitung (4,13) > Ztabel (1,645) yang berarti H0 ditolak dan Ha diterima. Berdasarkan hasil uji statistik kedua kelas sampel menunjukkan bahwa pembelajaran model pembelajaran penemuan (discovery learning) berbantuan handout memberikan pengaruh yang positif terhadap kemampuan berpikir kreatif dan hasil belajar kimia pada siswa kelas X IPA SMA Negeri 4 Mataram. Berdasarkan hasil observasi aktivitas siswa pembelajaran model pembelajaran penemuan (discovery learning) berbantuan handout berdampak positif dalam meningkatkan keaktifan siswa pada saat proses pembelajaran kimia pada siswa kelas X IPA SMA Negeri 4 Mataram.
Post-Partum Depression: A Literature Review
Authors: Alami Fathimah Nur , Maharani Nyoman Ayu Anindya , Balqis Ananda Amirah , Az-Zahra Falira Khoirunnisa , Zahira Lu’lu Al-Fatina , Tresna I Made Gyanendra Nanda , Amalia Emmy 
Published: January 2025

Post-partum depression (PPD) is a depressive episode that lasts up to four weeks after childbirth. Depression in mothers can affect various aspects of life, such as work, family, spouse, and children. There is a high incidence of suicidal thoughts in mothers who experience PPD, contributing significantly to maternal mortality rate. Understanding more about DPP is the main focus of this paper. This article utilizes a literature review method that collects sources from PubMed, Google Scholar, and Science Direct. This literature review explores various aspects of PPD including epidemiology, pathophysiology, clinical manifestations, diagnosis and treatment. Various physiological changes in the mother's body before and after childbirth increases the mother's vulnerabilities to mood disorders. The mechanisms of PPD involve various pathways, both external and internal. Internal factors include a decrease in certain hormones and neurotransmitters, a history of mental health disorders, and genetic predispositions. External factors include anxiety, external pressures, and lack of social support. The diagnosis of PPD can be established using the DSM-V and ICD-10 criteria. Treatment for PPD can involve both non-pharmacological and pharmacological therapies. PPD is a serious mental condition that causes various negative effects for both the mother and her family. The dysregulation of neuro-hormonal pathways is the primary mechanism in the pathogenesis of PPD. Effective diagnosis and appropriate treatment approaches are crucial in the management of PPD.
Deep Vein Thrombosis (DVT): A Literature Review
Authors: Kamila Alya Syafa , Ginuluh Gintis Dhimar , Syakir Syahda Aqila , Abida Aisya Nur , Balqis Ananda Amirah , Karlina Fairuz , Murniatin Rinesita , Farras Afif , Raihan Al Fikar , Putra Rian Akka Jaya , Arsyatt Maz Isa Ansyori 
Published: January 2025

Deep Vein Thromboembolism (DVT) occurs due to the formation of blood clots in the veins, characterized by the formation of thrombi along with an inflammatory response in the inner walls of the veins. DVT most commonly occurs in the deep veins of the lower extremities but can also occur, albeit less frequently, in other areas such as the arms or other forms of superficial thrombosis. This article aims to review the epidemiology, clinical presentation, diagnosis, pathophysiology, and management of deep vein thrombosis. The literature review was conducted by searching for relevant articles on deep vein thrombosis published in the past fifteen years. Literature searches were performed using Google Scholar, PubMed, and NCBI databases. The findings highlight the clinical manifestations of DVT and its potential to cause serious complications, particularly post-thrombotic syndrome. Post-thrombotic syndrome is a debilitating condition that can significantly impair patients' quality of life. Management of DVT involves both pharmacological and non-pharmacological treatments. Understanding the mechanisms of deep vein thrombosis and its management is crucial in minimizing the complications associated with this condition.
Marine Organisms with Anti-Amyloid Effect Through Their Role as BACE1 Inhibitors for Preventive Effort in Alzheimer’s Disease: A Literature Review
Authors: Putra Made Raditya Arhya , Saputri Legis Ocktaviana , Wicaksono Teguh Budi , Nugraha Kadek Nandita , Putri Ajeng Ayu , Salsabila Rika Kamila , Fidelia Puspa Zalika 
Published: January 2025

Alzheimer’s Disease (AD) is a gradually worsening neurodegenerative condition characterized by the build-up of beta-amyloid proteins, resulting in a decline in cognitive abilities. β-site amyloid precursor protein cleaving enzyme-1 (BACE1) is known to play a role in the formation of beta-amyloid plaques. Thus, theoretically, inhibiting BACE1 can potentially prevent and slow down the accumulation of these plaques. This study is a literature review that compiles data from various research examining the inhibitory effects of compounds from marine organisms on the BACE1 enzyme. A comprehensive analysis was conducted on the available literature to evaluate the potential of these compounds. 19 marine organisms and 40 compounds were identified with low IC50 values, five compounds with notably low IC50 values were identified: (1) 8,8’-Bieckol [1.62 µM] from Ecklonia cava, (2) Phlorofucofuroeckol A [2.13 µM] and (3a) Dieckol [2.21 µM] from Eisenia bicyclis, (4) bis-(2,3,6-tribromo-4,5-dihydroxybenzyl) ether [2.32 µM] from Symphyocladia latiuscula, (3b) another Dieckol [2.34 µM] also from Ecklonia cava and (5) Heparan sulfate [2.89 µM] from Portunus pelagicus. These findings underscore the therapeutic potential of marine compounds as BACE1 inhibitors for AD. However, further research is needed to explore their bioavailability and clinical efficacy for practical application in preventing and treating Alzheimer’s Disease.
Analysis of Community Structure in Essential Ecosystem Zones
Authors: Akbar Muhammad Firmansyah , Idris Muhammad Husni , Anwar Hairil 
Published: January 2025

Mangrove forest plant communities living in coastal areas have a significant influence on people’s lives ecologically and economically. As well as cultivating fisheries commodities and protecting coastal areas from abrasion and stroms, mangrove areas also play an important role in climat change issues. Due to their importance, some water and wetland areas with high conservation value are designated as Essential Ecosystem Areas. Lembar and Sekotong Bay is one of them. This study aims to observe the condition of plant structure and composition in essential areas as well as the environmental conditions that support plant growth. To do this, indices of density, relative density, frequency, relative frequency, dominance, and importance value index were taken from each mangrove species. This was done through vegetation analysis. The observation site consisted of six stations, each of which had 78 observation plot point. The results showed that there were seven mangrove species in the ecosystem area of importance: Rhizophora Apiculata, Rhizophora Stylosa, Rhizophora Mucronata, Bruguira Gymnorrhiza, Avicennia Marina, and Excoaria Agallocha. The highes species density and relative density were owned by Rhizophora Stylosa, and the lowest relative density was owned by Excoaria Agallocha. The Highest species frequency and relative frequency are own by Rhizophora Stylosa Overall, the condition of important mangrove area is still in the medium-dense category. Environmental factors such as temperature, saline, pH, and Humidity are very helpful for the growth of mangrove species.
Hormonal Contraception as a Meningioma Risk Factor: a Literature Review
Authors: Amaliya Annisa Risqi , Herpan Syafii Harahap  , Rohadi Muhammad Rosyidi  
Published: January 2025

Hormonal contraception is the most widely used contraceptive method in Indonesia, this is one of the risk factors for meningioma. Meningioma is the most common intracranial tumor. Risk factors for meningioma include a history of trauma, genetic history, hormonal exposure, history of menarche. in this study, the focus is on discussing literature on hormonal contraceptive exposure. This paper is a literature review. The method used in this literature review is to search and review various literature sourced from online databases such as PubMed, Google Scholar, and Proquest. The keywords used in the literature search process include “hormonal”, “contraception”, “progesterone” “meningioma”. The use of hormonal contraceptives has been shown to increase the risk of meningioma, which is attributed to the progesterone receptors present in the normal meningens and the presence of the same progesterone receptors in meningiomas. The results of older studies have different results from recent studies, these inconsistencies may be associated with other variables such as duration, dose, and consistency in use, differences in the type of contraceptive use, current or previous use and other risk factors, further research needs to examine these variables and the underlying hormonal mechanisms to obtain more accurate results.
Formulation and Effectiveness Test of Liquid Soap from Siam Weed (Chromolaena odorata (L.) Leaves Ethanol Extract Against Staphylococcus aureus
Authors: Diana Vivi Eulis , Abadi Hafizhatul , Andry Muhammad 
Published: January 2025

Chromolaena odorata (L.) is one of the plants known as weeds. Alkaloids, flavonoids, saponins, tannins, and glycosides are active chemicals found in Siam weed leaves. The study aimed to see if an ethanol extract of Siam weed leaves can be made into liquid soap and has antibacterial action against Staphylococcus aureus germs. The liquid soap of Siam weed (Chromolaena odorata L.) leaf ethanol extract at concentrations of 3%, 6%, and 9% was carried out experimentally in the laboratory, along with physical liquid soap evaluation tests such as organoleptic test, homogeneity test, pH test, foam height test, specific gravity test, test irritation, and hedonic test. Staphylococcus aureus bacteria were then tested. The assessment test criteria were met by making liquid soap preparations of ethanol extract of Siam weed leaves at concentrations of 3%, 6%, and 9%. The color of the solid soap was brown - dark brown, and the texture was liquid with a lemon scent; the homogeneity test showed that all preparations were homogeneous; the pH test of the soap was 9.1 -9.7; the foam height test was 53-66 mm; the specific gravity test was 1-1.01 g/ml; and the irritation test revealed that all preparations had no reaction to redness, itching, and swelling on the skin. The hedonic test on skin revealed that all preparations obtained favorable evaluations from the panelists. The antibacterial activity of liquid soap against Staphylococcus aureus germs was F1 3.65 mm, F2 5.75mm, and F3 6.5mm. Based on the results of the Staphylococcus aureus test, it could be concluded that in the formula F1 (3% concentration), F2 (6% concentration) and F3 (9% concentration) had an inhibition zone.
Biodiversitas Lamun (Seagrass) di Pesisir Kecamatan Pulutan Kabupaten Kepulauan Talaud Sebagai Database Keanekaragaman Hayati di Propinsi Sulawesi Utara
Authors: Maabuat Pience Veralyn , Kolondam Beivy Jonathan , Langoy Marnix L. D. , Loho Jesica C. M. , Makagansa Marbela 
Published: January 2025

Lamun (Seagrass) merupakan tumbuhan tingkat tinggi yang berbeda dengan alga (Seaweed). Ekosistem padang lamun memiliki fungsi penting di lingkungan perairan bagi biota yang hidup di laut. Ekosistem Padang Lamun berfungsi sebagai habitat bagi berbagai biota laut, termasuk ikan kecil, Moluska, dugong dan penyu. Lamun menjadi sumber makanan, menjadi tempat asuhan dan tempat berlindung, selain itu sebagai tempat sirkulasi nutrien Begitu juga dari segi manfaatnya secara ekonomis tinggi dengan dimanfaatan sebagai bahan obat tradisional sampai dijual dalam bentuk kerajinan tangan. Penelitian menyangkut ekosistem ini masih kurang memperoleh perhatian dibandingkan dengan ekosistem Mangrove dan Terumbu Karang, padahal secara fungsional penting dan saling berhubungan erat di pesisir. Selain itu informasi data masih kurang sehingga perlu dilakukan suatu penelitian untuk memperoleh informasi berupa data base keanekaragaman lamun di perairan Indonesia. Lamun tumbuh di Pantai Desa Pulutan Kabupaten Kepulauan Talaud, akan tetapi belum ada informasi tentang keberadaannya. Penelitian dilakukan pada bulan Mei 2024 pada saat surut terendah dengan menggunakan metode Purposive random sampling. Hasil penelitian menemukan tiga jenis lamun yaitu Thalassia hemprichii, Cymodocea serrulata dan Cymodocea rotundata. Indeks keanekaragaman diperoleh H’ = 0.99 dengan keanekaragaman rendah
Saluran Pemasaran Ternak Ayam Broiler di Kelurahan Tiakur Kecamatan Moa Kabupaten Maluku Barat Daya
Authors: Yermias Atalia , Jesajas Heryanus , Alam Asmirani 
Published: January 2025

This study aims to find out the form of the Broiler Chicken Marketing Channel in Tiakur Village, Moa District, Southwest Maluku Regency. This research was carried out in June-August 2024 in Tikur Village. This research was conducted on broiler chicken farmers, collectors and retailers who were traced using the snowball sampling method. This study uses 6 broiler chicken farming businesses in Tiakur Village as respondents and the design used is a descriptive design. The results of the study show that most businesses from broiler chicken farms use short marketing channels compared to long marketing channels. In addition, based on the results of the study, it also shows that the broiler chicken marketing channel in Tiakur Village, Moa District, Southwest Maluku Regency has various problems, including limited market access, high transportation costs, demand, competition with other products, lack of knowledge about marketing strategies, product quality problems and too many intermediaries.
From Producer to Peripheral to Periphery and Back
Authors: Fraunholtz Peter 
Published: January 2025

Abstract
This article explores the fitful evolution of the procurement system in Penza, a nominal grain producer enduring persistent food-supply crises resulting from both a poor harvest and dependence on weak state grain redistribution. In examining the dynamics involved in Bolshevik centralizing efforts of summer 1918, this article investigates the twelve months following the poor 1917 Volga harvest. It explores how provincial authorities in Penza struggled to maintain control over local organs as access to external grain sources dwindled and then collapsed in June 1918. Penza transitioned from peripheral, dependent on the grain-rich periphery, to Soviet periphery, critical for procurement where militant Bolsheviks, desperate for procurements pressed forward with little local knowledge and without overwhelming force. This article places the Kuchki uprising at the intersection of post-1917 harvest dynamics and the pre-harvest push to fortify central authority. It builds on and complicates previous scholarship on civil war-era procurement typically focused on Russia’s grain-rich “producer” provinces.
TINJAUAN KESIAPAN PENERAPAN REKAM MEDIS ELEKTRONIK DALAM SISTEM INFORMASI MANAJEMEN GUNA MENUNJANG EFEKTIVITAS PELAYANAN DI RSAU LANUD SULAIMAN
Authors: Arya Arya adhari akbar , Wahab Syaikhul 
Published: January 2025

Perkembangan tehnologi di era modern saat ini sangatlah pesat, pertumbuhan informasi di berbagai bidang telah menjadi fenomena yang terjadi di seluruh dunia, dalam bidang kesehatan pun tehnologi sudah dikembangkan salah satunya dengan penggunaan Rekam Medis Elektronik (RME). Penggunaan sistem tersebut sangat efisien dan efektif karna memudahkan dalam pelayanan pasien. Penelitian ini bertujuan untuk menilai Tinjauan Kesiapan Penerapan Rekam Medis Elekgtronik dalam sistem informasi manajemen guna menunjang efektifitas pelayanan di RSAU Lanud Sulaiman yang di nilai dengan Metode 5M Man, Money, Material, Methode, Machine, Penelitian ini merupakan penelitian kualitatif dengan pendekatan deskriptif untuk mengumpulkan informasi secara menyeluruh mengenai kesiapan penerapan rekam medis elektronik dalam system informasi manajemen guna menunjang efektifitas pelayanan di RSAU Lanud Sulaiman, penelitian ini dilakukan dengan wawancara kepada tiga orang petugas rekam medis yang dipilih secara kebetulan. Hasil penelitian ini secara keseluruhan RSAU Lanud Sulaiman sudah siap dalam penerapan RME Adapun dua asfek yang teridentifikasi sebagai area yang perlu ditingkatkan pertama dalam aspek Man (Manusia) terdapat kekurangan SDM yang berkelanjutan. Kedua dalam hal sarana dan prasarana ada beberapa sarana yang perlu ditambahkan seperti mesin komputer dan mesin cetak printer demi menunjang keberhasilan pelayanan dalam penerapan RME. Untuk dapat meningkatkan pelayanan dalam penerapan RME dengan sistem informasi maka dibutuhkan koordinasi baik dari pihak pengguna dengan penyedia serta meningkatkan keahlian dengan pelatihan secara berkala.
TINJAUAN TRANSISI REKAM MEDIS MANUAL MENUJU ELEKTRONIK GUNA MENUNJANG EFEKTIVITAS REKAM MEDIS DI RUMAH SAKIT EDELWEISS BANDUNG
Authors: Al Wafi Firki , Wahab Syaikhul 
Published: January 2025

Di era informasi saat ini, akses yang cepat dan akurat terhadap data pasien menjadi sangat penting. Rekam medis elektronik (RME) menawarkan solusi yang efektif untuk memenuhi kebutuhan tersebut. Penelitian ini akan mengkaji bagaimana rumah sakit menjalai proses transisi rekam medis manual menuju elektronikStudi ini menggunakan pendekatan penelitian kualitatif. Penelitian kualitatif ini mengumpulkan data di Rumah Sakit Edelweiss Bandung dari Maret hingga Mei 2024 melalui wawancara dan observasi terhadap dua informan penting. Data dianalisis secara deskriptif untuk menemukan analisis tinjaun transisi rekam medis. Dari hasil penelitian penulis menyimpulkan bahwa proses transisi rekam medis manual menuju elektronik di lakukan dengan membentuk tim pengimplementasian rekam medis elektronik termasuk bagian rekam medis, tim IT, pelayanan dan keperawatan. Dengan kekurangan dan kelebihannya rekam medis manual bergantung pada beasaran ruangan, rak penyimpan. Namun pada rekam medis elektronik memiliki kekurangan kesulitan dalam tanda tangan elektronik belum tersertivikasi menjadikan validasi tandatangan menjadi sulit di lakukan. Kekurangan SDM juga sangat berpengaruh terhadap efektivitas pelayanan menjadikan perekam medis di rumah sakit edelweiss bekerja secara overtime/lembur. Secara keseluruhan transisi rekam medis manual menuju elektronik di perlukan peningkatan kapasitas ruangan penyimpanan dan rak berkas rekam medis, penambahan SDM dan tandatangan elektronik yang sudah terverivikasi.
HUBUNGAN METODE DISTRAKSI VISUAL TERHADAP NYERI PADA PEMASANGAN INFUS ANAK PRA SEKOLAH DI INSTALASI GAWAT DARURAT RUMAH SAKIT UMUM CUT MEUTIA LHOKSEUMAWE
Authors: Ardilla Arista , Zulkarnaini Zulkarnaini , Utaminingsih Eka , Effendi Desy Iradillah , Fatmawati Fatmawati 
Published: January 2025

Reaksi anak dalam mengatasi krisis dipengaruhi oleh tingkat perkembangan anak, diantar lain : usia, pengalaman sebelumnya terhadap proses sakit dan dirawat. Anak usia prasekolah sangat sulit untuk memahami prosedur invasif yang dapat menyebabkan nyeri seperti saat pemasangan infus. Penelitian ini menggunakan metode analitik bertujuan untuk mengetahui hubungan antara variable dimana veriabel independen dan variable dependen diidentifikasi pada satu waktu yang bersamaan. Berdasarkan katagori usia mayoritas perempuan sebanyak 57 orang (54,3%). Berdasarkan katagori umur mayoritas 3-4 tahun sebanyak 83 orang (79%). Pemasangan infus metode distraksi visual anak pra sekolah di Instalasi Gawat Darurat Rumah Sakit Umum Cut Meutia Lhokseumawe mayoritas efektif sebanyak 93 orang (88,6%). Tingkat Nyeri pada pemasangan infus anak pra sekolah di Instalasi Gawat Darurat Rumah Sakit Umum Cut Meutia Lhokseumawe mayoritas nyeri sedang sebanyak 64 orang (61%). Hasil analisis bivariat menggunakan uji Chi-square penurunan nyeri dengan tingkat kepercayaan 95% (? 0,05) nilai p value atau nilai Asymp. Sig. (2-sided) yaitu 0.001 artinya nilai P value 0.001 ? 0.05. Hal ini menunjukan bahwa ada hubungan yang signifikan antara metode distraksi visual terhadap nyeri pada pemasangan infus anak pra sekolah di Instalasi Gawat Darurat Rumah Sakit Umum Cut Meutia Lhokseumawe. Diharapkan kepada pihak Rumah Sakit agar hasil penelitian ini dapat dijadikan acuan dalam terapi nonfarmakologi pada anak saat tindakan invasif terutama pemasangan infus.
ANALISIS DETERMINAN PEMBEDA RISIKO PPOK PADA PELAJAR SMKN 1 RUNGAN HULU
Authors: Sitorus Ricky Richardo , Elinaria Elinaria , Lovenia Lovenia , Renita Renita , Darmawanto Retno , Rifaldi Rifaldi 
Published: January 2025

Perubahan tren penyakit tidak menular sekarang condong terhadap populasi berusia muda. Hal ini dikarenakan kecenderungan peningkatan perilaku tidak sehat. Penyakit yang muncul karena potensi tersebut salah satunya Penyakit Paru Obstruksi Kronis (PPOK). Prevalensi PPOK di Kabupaten Gunung Mas melebihi prevalensi Nasional dengan penemuan kasus condong pada wilayah pedesaan. PPOK merupakan salah satu 10 penyakit terbanyak di Puskesmas Tumbang Rahuyan. Determinan risiko PPOK seperti aktivitas fisik yang jarang dan konsumsi rokok serta alkohol juga meningkat dalam skala nasional dan regional provinsi Kalimantan Tengah terutama pada populasi remaja. SMKN 1 Rungan Hulu merupakan satu-satunya Sekolah Lanjut Tingkat Atas di Kecamatan Rungan Hulu yang berada di Wilayah Kerja Puskesmas Tumbang Rahuyan. Tujuan penelitian ini adalah menganalisis determinan pembeda risiko PPOK pada pelajar SMK Negeri 1 Rungan Hulu. Penelitian ini merupakan penelitian analitik komparatif dengan rancangan studi potong lintang. Populasi dan sampel penelitian ini adalah seluruh pelajar SMK Negeri 1 Rungan Hulu. Teknik pengambilan sampel menggunakan teknik sampling konsekutif dengan jumlah 130 responden. Penelitian ini menggunakan instrumen kuesioner PUMA, dimana skor PUMA sebagai variabel bebas. Sedangkan jenis kelamin, rentang usia, aktivitas fisik, konsumsi rokok dan konsumsi alkohol sebagai variabel terikat. Analisis data menggunakan Mann-Whitney U Test. Hasil analisis bivariat menunjukkan adanya perbedaan bermakna pada jenis kelamin (p<0,001), aktivitas fisik (p=0,024) dan konsumsi rokok (p<0,001) serta konsumsi alkohol (p<0,001) terhadap risiko PPOK pada pelajar SMKN 1 Rungan Hulu. Hal berbeda ditampilkan pada variabel rentang usia tidak menunjukkan perbedaan yang bermakna (p=0,686) terhadap risiko PPOK pada pelajar SMKN 1 Rungan Hulu.