bluuebunny/crossref_metadata_2025_split huggingface dataset:
Botulinum toxin type A in treatment of chronic migraine, spasticity and bruxism
Authors: Kuliga Klaudia , Dobko Katarzyna , Frącz Gabriela , Glac Agata , Musz Kinga , Sejnowska Natalia , Socha Agnieszka , Surowiec Agata , Śnieżek Kinga , Zając Anna 
Published: May 2023

Introduction: Nowadays, botulinum toxin has found use in many disease entities such as chronic migraine, spasticity, bruxism and many others. Among serotypes A-E, type A is mainly used in treatment. For the therapeutic effect to be maintained, injections need to be repeated most often after 12 weeks. More frequent injections of the toxin may result in the production of neutralizing antibodies.
Aim of the study: The aim was to collect and analyze publications of application of botulinum toxin type A (BT-A) in the treatment of chronic migraine, spasticity and bruxism.
Methods and materials: We reviewed the literature available in the PubMed database using the key words: “botulinum toxin”; “migraine”; “spasticity”; “bruxism”.
Results: The use of botulinum toxin type A in patients with chronic migraine reduces the frequency of pain episodes and alleviates the symptoms. BT-A therapy reduces increased muscle tension, resulting in improved function of the upper or lower limb, facilitating the rehabilitation process, reducing pain associated with spasticity and protecting against the development of muscle contractures and secondary joint deformities. BT-A treatment of patients with bruxism reduces the level of pain and the maximum generated bite force, resulting in an improved quality of life for patients.
Conclusion: Intramuscular administration of botulinum toxin is a safe, effective and minimally invasive method of treating chronic migraine, spasticity and bruxism. The botulinum toxin type A is the most studied serotype used for therapeutic purposes. Future research on botulinum toxin will certainly allow wider use.
CPR-induced consciousness (CPR-IC) out-of-hospital care: a scoping review protocol
Authors: Silvestri Lucymarie , Soh Rachel , Newton Alexander , Pearce James 
Published: May 2023

Introduction: Cardiopulmonary resuscitation-induced consciousness (CPR-IC) is an increasing phenomenon where patients in cardiac arrest receive sufficient brain perfusion to display signs of awareness during resuscitation. This is likely due to improvements in CPR, such as high-performance resuscitation and mechanical devices. CPR-IC has been shown to interfere with rescue efforts and may lead to psychological trauma in both patients and clinicians. It is often witnessed in the out-of-hospital environment, so is significant for practitioners working in this setting. While the phenomenon of CPR-IC has been recognised for several decades, there are many gaps in the literature and no consensus has been reached over its definition or management. Methods: The JBI scoping review methodology will be used to map the existing literature and identify the extent of clinical knowledge and any gaps regarding the management of CPR-IC in out-of-hospital cardiac arrest globally. A comprehensive electronic search strategy will be employed to source works that meet to the study’s inclusion criteria. Relevant data will then be extracted and presented in tabular form with narrative descriptions. Discussion: CPR-IC is being seen more frequently and, because of its effects on resuscitation, more knowledge is required about appropriate management. This protocol provides the framework for a scoping review which will outline the extent of knowledge and identify areas requiring more research regarding out-of-hospital care of the patient with CPR-IC.
Identifying and managing osteoporosis: a role for nurses
Authors: Hawarden Ashley , Paskins Zoe 
Published: May 2023

Osteoporosis is the most common metabolic bone disease that will be encountered by nurses in both primary and community care. Ashley Hawarden and Zoe Paskins look at how the condition can be managed in a primary care setting Osteoporosis is the most common metabolic bone disease. Primary care nurses play an essential role in both primary and secondary prevention of osteoporosis. In this article Ashley Hawarden and Zoe Paskins will provide an overview of osteoporosis, investigation and management and provide guidance for when to refer for specialist advice.
Distribución y caracterización de los diques del Geoparque Mixteca Alta-UNESCO como evidencia de un régimen tectónico extensional en el oeste de Oaxaca, México
Authors: Barrientos Zavala Karen Jazmín , Chako Tchamabe Boris , Silis Esquivel Jhoanna , Alcalá Reygosa Jesús , De Castro Martinez Gonzalo Fernández , Marín Guzmán Ana Pilar , Montes de Oca Alejandro 
Published: May 2023

El Geoparque Mundial UNESCO Mixteca Alta (GMUMA), localizado en la porción occidente del estado de Oaxaca, al sur de México, se destaca por una variedad de rasgos geológicos y geomorfológicos, algunos representados por cuerpos ígneos intrusivos. Entre ellos están los diques expuestos en las localidades de Santo Domingo Tonaltepec, Santo Domingo Yanhuitlán y San Pedro Añañé. Estos cuerpos tabulares cortan discordantemente las rocas del subsuelo, y suelen desarrollarse en enjambres de diques individuales con orientaciones paralelas, lineares o radiales bajo la influencia de otros eventos tectónicos o estructura geológicas.
En este trabajo se identifican y cartografían los diques del GMUMA a través del análisis de imágenes satelitales, complementado con observaciones en campo donde se cotejó su presencia y se identificaron los rasgos geológico-estructurales asociados. Así mismo, con ayuda del programa Stereo32 1.0.1, se graficaron un total de 66 rumbos de los diques y se elaboraron diagramas de rosas para visualizar la dirección preferencial de los diques y relacionarlo con el régimen tectónico de la región.
Se identificaron 3 grupos de diques con trazas longitudinales que varían desde unos pocos metros hasta 1 km y con grosores aproximados de entre 4 y 5 m, con una dirección preferencial hacia el noroeste. Los diques exhiben tres tipos de morfologías: planares, escalonados y trenzados, cuyas interpretaciones y direcciones permitieron establecer que los diques están asociados a un evento tectono-magmático de tipo extensivo que se mantuvo activo durante el Eoceno, con una dirección preferencial hacia el noroeste-sureste, similar a la orientación de las fallas Tamazulapan y Cieneguilla.
İNSAN KAYNAKLARI ROLLERİNİN ÖRGÜT KÜLTÜRÜNE ETKİSİ
Authors: ERDUYGUN Zekiye , TINAZ Pınar 
Published: May 2023

Bu çalışmada insan kaynakları rolleri ile örgüt kültürü arasındaki ilişkilerin incelenmesi amaçlanmış olup insan
kaynakları rollerinin dört alt boyutunun örgüt kültürüne etkisi araştırılmaktadır. Ayrıca, katılımcıların demografik
özelliklerine göre insan kaynakları rolleri algı düzeylerinin ve örgüt kültürü algı düzeylerinin farklılaşıp
farklılaşmadığı da araştırılan bir diğer konudur. Araştırmanın evreni, bir hazır giyim üretim kurumunun 400
çalışanından oluşmaktadır. Araştırmanın örneklemi ise, araştırmaya katılmaya gönüllü olan 200 katılımcıdır.
Araştırmanın verileri anket yöntemiyle toplanmış olup veriler, çoklu regresyon, bağımsız örneklem t testi ve tek
yönlü varyans analizi (ANOVA) gibi nicel yöntemlerle analiz edilmiştir. Araştırma bulguları, insan kaynakları
rollerinin stratejik ortak ve çalışan şampiyonu alt boyutlarının örgüt kültürünü pozitif yönde etkilediğini
göstermiştir. Diğer taraftan insan kaynakları rolleri alt boyutlarından idari uzman ve değişim ajanı alt
boyutlarının örgüt kültürü üzerinde anlamlı bir etkisi bulunmamıştır. Örgüt kültürünün algılanması çalışanların
demografik özelliklerine göre farklılaşmamaktadır. İnsan kaynakları rolleri alt boyutlarının da yaşa, örgütteki
pozisyona, mesleki ve örgüt kıdemine göre farklılık göstermediği saptanmıştır. Cinsiyet ve eğitim düzeyi
değişkenleri açısından bazı insan kaynakları rolleri alt boyutlarının kadınlar ve yüksek düzeydeki eğitimliler
lehine farklılaştığı gözlenmiştir.
ANALISIS RISIKO PADA TAHAP PELAKSANAAN KONSTRUKSI JALAN TOL CINERE – JAGORAWI, DEPOK
Authors: Faisal Muhammad 
Published: May 2023

Cinere-Jagorawi Toll Road is a part of Jakarta Outer Ring Road (JORR) II which has the total length of 110 kilometer that circle around Seokarta-Hatta International Airport until Tanjung Priok. By the existance of JORR II, there would be an easy access from seaport to airport and vice versa. This also would be streamlining traffic flow from west to east considering the traffic at JORR I has overused which could cause congestion. In every construction of the Toll Road, there would be some risks that possibly arise. To minimize the risks that could occur, identification, anlysis, mitigation and allocation towards the possible risks – especially the risks which are classified in dominant category - are essential. This is expected to be a basis of decision making by stakeolders to resolve negative consequences that happen during the construction of Toll Road. In this research, the researcher uses qualititive descriptive research with survey method using questionnaire as a research instrument. According to the result of questionnaire, there were 45 risks identified in this research. After acquiring the result from questionnaire, the next step were determining validity and reliability, and analysing the acceptance of the risks to identify which risks are classified as domminant risks factor. There were 8 (18%) risks classified as Unacceptable Category and 37 (82%) risks classified as Undesireble Category. The next step was mitigating the risks included in domminant risk factors. Based on risk mitigation, ownership risk management should be carried out by the stakeholeders involved in Toll Road construction.
ANALISIS MANAJEMEN RISIKO PADA PROYEK PEMBANGUNAN BENDUNGAN (STUDI KASUS : BENDUNGAN TITAB DI BALI, BENDUNGAN JATIBARANG DI KABUPATEN SEMARANG DAN BENDUNGAN DIPONEGORO DI SEMARANG)
Authors: Wayangkau Helen Gianditha 
Published: May 2023

ABSTRACTConstruction of dam project has complicated characteristics, as a result it has varios kinds of risks that influential the implementation. The larger scale of the project makes the risk of project potential more growing, so it needs a risk management in order to minimize the potential risk.In general to manage the risk management, stakeholders are often analysed it by using Risk Breakdown Structure method (RBS). However by using RBS is not sufficient because it just to get a risk category. It necessary the level of risk analysis by PROMETHEE method to find out priority major rangking on construction project.To support and improve the management of dam project development activity, it implemented risk assesment. As many as 31 variabels risk related to the project was successfuly identified. The survey through quistionares have sent to 1 expert who representative of the owner on ministry of public works, directorat of water resources and 1 expert in private companies who have experience in each of dam, also taken 1 people around the located who was affected by the impact directly. This research used quantitative descriptive method.The result of this research were obtained that the risk of social environment is the highest potential risk which is almost same in every project.The risk of social environment is alocated to the government because the review of land acquistion depended with the authority and the policy of the authorities. In addition it obtained a low and high a risk that happened in research field refers to the impact not about the probability. If the probability is low and the impact is high then the risk goes highest. Preferably in a high probability and its impact is low then the risk is insignificant.Keywords : Management Risk, PROMETHEE, Risk, Risk Breakdown Structure.
Analisa Kapasitas Struktur Intake Rumah Pompa Karang Anyar, Pulokerto
Authors: Costa Anthony , Yudi Ahmad 
Published: May 2023

Intake Building Structure is a Pier Type Structure that is used as a building for the distribution of clean water. This structure stands on a stake that stands on the edge of the river, as a pier-type building that accepts the load of river currents and pump vibration loads, it is necessary to analyze the maximum capacity, economical and also sturdy. There are several important aspects that must be reviewed to get the maximum design, including water current load, soil load, pump vibration load and also earthquake load in the form of spketrum response based on Palembang area. The design reference used is SNI1727-2013 and SNI 1726-2002. Based on the analysis, the intake structure was obtained in the form of reinforced concrete structures on the floor area and pilecap while for the foundation of the stake in the form of composite steel, columns and beams because it supports a heavy enough load, the profile steel is used.
Realizm dźwiękowy i muzyczny w grach wideo o kontekście historycznym
Authors: Pietruszewski Paweł 
Published: May 2023

Muzyka i dźwięk w grach wideo o kontekście historycznym w znacznej części bazują na memicznych skojarzeniach świadomości zbiorowej. O ile konteksty realizmu wizualnego i narracyjnego są dobrze przebadane, o tyle kwestia realizmu dźwiękowego gier historycznych wymaga głębszej analizy. Artykuł próbuje dać odpowiedź na następujące pytania: jak mocno warstwa muzyki zbliża gracza do rzeczywistej muzyki okresu historycznego, w którym toczy się akcja gry? Jakie zabiegi dźwiękowe decydują o tym, iż przeciętny gracz jest w stanie rozpoznać ścieżkę dźwiękową z punktu widzenia historycznego i geograﬁcznego? W tekście przyglądam się zagadnieniu pod kątem użycia w grach form muzycznych zgodnych z daną epoką historyczną oraz w odniesieniu do instrumentarium historycznego i ulokowania geograﬁcznego. Świadome wyważanie tych elementów przez twórców przyczynia się do głębszego zanurzenia gracza w epoce i miejscach, w których toczy się rozgrywka. Tym samym należy do elementów potęgujących immersję.
Chloramine-T-induced oxidation of Rizatriptan Benzoate: An integral chemical and spectroscopic study of products, mechanisms and kinetics
Authors: Malini S. , Raj Kalyan , Kumari Latha , Jayant Lakshmi , Shettihalli Ashok Kumar , Appaji Abhishek 
Published: May 2023

Abstract
Oxidation is a prominent degradation route of biological molecules that produces a wide variety of degradation products through complex mechanisms and hence qualifies to be a vital pharmaceutical process. This article presents the kinetic and spectral study of the oxidation of an antimigraine drug rizatriptan benzoate (RTB) in an acid medium with the aid of a mild biocidal oxidant N-chloro-p-toluenesulfonamide, referred to as chloramine-T (CAT). The kinetic experimental studies reported here, such as fractional order dependency on RTB, pseudo-first-order dependency on CAT, negative fractional order dependency on the acid medium, independent of the rate on the ionic concentration and increasing rate with increasing dielectric constant, have led to the evaluation of stoichiometry, thermodynamic properties, and derivation of a rate equation. Effective interpretation of UV–Vis, IR, 1H and 13C NMR investigation was performed to identify and confirm the identity of the oxidation products and discuss the involved plausible mechanism. This study provides an extended insight into the products of oxidation formed during the metabolism of RTB.
Hemp seed oil nanoemulsion with Sapindus saponins as a potential carrier for iron supplement and vitamin D
Authors: Smułek Wojciech , Jarzębski Maciej 
Published: May 2023

Abstract
Vitamin D3 and iron are important components of a balanced diet. Supplementing meals with these is essential to support the recovery of humankind’s malnutrition. It is necessary to develop effective delivery systems to ensure the high bioavailability of these hydrophobic components. For this purpose, emulsions were prepared based on hemp seed oil and with soap nut extract (Sapindus mukorossi fruits) as a natural emulsifier. To characterize the differences in the properties of the emulsions depending on the content of the oil phase and the emulsifier, measurements were performed to determine the following parameters: the color characteristics, transparency of the samples, infrared spectrum, particle size distribution, polydispersity of the system, and the rheological properties of the emulsions. The results showed that the highest stability was observed in systems with a relatively low oil concentration, i.e., 1%. These samples also had an average particle size not exceeding 200 nm. In turn, the low oil content significantly reduced the dynamic viscosity of the emulsions. At the same time, microscopic observations indicated that the presence of an oil phase was advantageous, not only because of the possibility of providing vitamin D but also because of the high hydrophobicity of the iron particles. Therefore, the realized research made it possible to identify the optimal emulsion composition. The created system can find applications in delivering dietary supplements such as vitamin D3 and iron by providing high dispersion of components and high stability.
Stricter Community Supervision, More Recidivism? An Ego-Depletion Theory
Authors: Mungan Murat C. 
Published: May 2023

Abstract
Can stricter community supervision (i.e., parole and probation) requirements lead to an increase in recidivism? I investigate this question by constructing a law enforcement model in which individuals can incur costs to increase their degree of self-control. The analysis reveals that stricter community supervision can, in fact, increase recidivism if these investments lead to ego-depletion. This possibility therefore warrants empirical investigation, and policy makers ought to be mindful of it when determining the strictness of community supervision conditions.
Caribe Alucinante
Authors: Urrely Angel 
Published: May 2023

Leo las entrañas de la urbe, y dejo escrito en sus paredes imaginarias mi paso por la ciudad primada de América en su segunda ubicación, después de que una plaga de hormigas Caribe la hiciera mudar a la ribera occidental del rio Ozama. En cada cuadrícula del mapa van a parar, siguiendo las leyes del azar, estructuras claustrofóbicas, formando campos deportivos que en el caso del beisbol vendrían a ser una fábrica de sueños a la que acuden padres y niños con la esperanza de salir de pobres. En el cuerpo de la ciudad queda una especie de queloide: los diseños de rejas soportando el peso del hierro bajo las formas más promiscuas. La cotidianidad está marcada por la suerte de cruzar indemne el laberinto de calles casi sin aceras, donde el acto de caminar es una penitencia de escolar que repite la misma oración para que el cansancio deje sentir el peso del castigo. La ciudad le da la espalda al mar y un espejismo de isla artificial surge en el horizonte, como la ballena de Simbad el marino cuando la confundió con tierra firme, y sobre la cual habían crecido hierbas y árboles. Frente al agua nacen edificios que se nublan de campos de beisbol en las azoteas. El vértigo haría caer a los jugadores al vacío, si no se dieran cuenta de que estos estadios no tienen muros de contención.Caribe Alucinante Resumo:Leio as entranhas da urbe e deixo escrito em suas paredes imaginárias meu caminhar pela primeira cidade da América em sua segunda localização, depois de ser obrigada a mudar-se para a margem ocidental do rio Ozama por praga de “formigas-de-fogo”. Em cada quadrícula do mapa elas acabam, seguindo as leis do acaso, estruturas claustrofóbicas, compondo campos esportivos que, no caso do beisebol, se transformam em fábricas de sonhos para quais vão pais e filhos na esperança de sair da pobreza. No corpo da cidade resta uma espécie de queloide: o traçado das grades que sustentam o peso do ferro sob as formas mais promíscuas. A vida cotidiana está marcada pela sorte de atravessar incólume o labirinto de ruas quase sem calçadas, onde o ato de caminhar é como uma penitência escolar, repetindo a mesma oração para que o cansaço faça sentir o peso do castigo. A cidade dá as costas ao mar e a miragem de uma ilha artificial surge no horizonte como a baleia do marinheiro Simbad, que a confundiu com terra firme, sobre a qual ervas e árvores haviam crescido. Defronte à água nascem edifícios que são obscurecidos por campos de beisebol em seus telhados. A vertigem faria os jogadores cair ao vazio, se não se dessem conta de que esses estádios não possuem muros de contenção.
La manipulación temporal en el lenguaje audiovisual de la frontera norte, a partir de la revisión de dos casos de estudio
Authors: Jiménez Mayra Huerta 
Published: May 2023

El lenguaje audiovisual lo acotamos al vídeo experimental, que se genera en la ciudad de Tijuana. A partir de la revisión de los artistas audiovisuales: Aldo Guerra y Julio Orozco para analizar la manipulación temporal en su producción audiovisual. Desde un acercamiento geográfico y etnográfico en el espacio fronterizo, el método de análisis que proponemos ubica a los artistas en continuo movimiento, con posibles desplazamientos en su clasificación. En esta ocasión presentaremos la clasificación en la que se ubican, así como el desarrollo de su producción audiovisual. A partir de la diferenciación y uso del tiempo que generan. Desde el enfoque de Nicolas Bourriaud en su libro Radicante, que plantea prácticas portátiles y actos de traducción en el arte contemporáneo es que nos interesa estudiar estos dos artistas audiovisuales. Y al mismo tiempo ubicarlos dentro de una condición nómada. El estudio del vídeo como medio de creación en el espacio fronterizo, tiene acercamientos interdisciplinarios y en un aspecto móvil que nos interesa retomar para la clasificación del vídeo experimental en Tijuana. Temporal manipulation in the audiovisual language of the northern border, the review of two case studiesAbstract:Audiovisual language is limited to the experimental videos generated in the city of Tijuana. In reviewing audiovisual artists: Aldo Guerra and Julio Orozco, the temporal manipulation in their audiovisual production is analyzed. Using a geographic and ethnographic approach to the border area, the analytical method that we have proposed locates artists in continuous movement, noting possible displacements in their classification. In this paper, we will present the classification in which they are located, as well as the development of their audiovisual production, based on the differentiation and use of time generated. The emphasis that most interests us in studying these audiovisual artists is the approach used by Nicolas Bourriaud in his book Radicant, which proposes portable practices and acts of translation in contemporary art. And at the same time, these are seen under nomadic conditions. The study of video as a creative medium in the border area has interdisciplinary approaches and a mobile aspect that interest us as we reconsider the classifications of experimental video in Tijuana.