bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recent Thymic Emigrants Require RBPJ-Dependent Notch Signaling to Transition into Functionally Mature Naive T Cells
Authors: Teichman Sintia , Wang Helen , Lee Christina R , Mohtashami Mahmood , Foerster Elisabeth , Han Jianxun , Trotman-Grant Ashton C , Winer Shawn , Tsui Hubert , Philpott Dana J , Zúñiga-Pflücker Juan Carlos 
Published: May 2023

Abstract
Recent thymic emigrant (RTE) cells are nascent T cells that continue their post-thymic maturation in the periphery and dominate T cell immune responses in early life and in adults having undergone lymphodepletion regimens. However, the events that govern their maturation and their functionality as they transition to mature naive T cells have not been clearly defined. Using RBPJind mice, we were able to identify different stages of RTE maturation and interrogate their immune function using a T cell transfer model of colitis. As CD45RBlo RTE cells mature, they transition through a CD45RBint immature naive T (INT) cell population that is more immunocompetent but shows a bias toward IL-17 production at the expense of IFN-γ. Additionally, the levels of IFN-γ and IL-17 produced in INT cells are highly dependent on whether Notch signals are received during INT cell maturation or during their effector function. IL-17 production by INT cells showed a total requirement for Notch signaling. Loss of Notch signaling at any stage of INT cells resulted in an impaired colitogenic effect of INT cells. RNA sequencing of INT cells that had matured in the absence of Notch signals showed a reduced inflammatory profile compared with Notch-responsive INT cells. Overall, we have elucidated a previously unknown INT cell stage, revealed its intrinsic bias toward IL-17 production, and demonstrated a role for Notch signaling in INT cell peripheral maturation and effector function in the context of a T cell transfer model of colitis.
Stressful Major Life Events and Chronic Urticaria
Authors: Choudhari Preeti Ganesh , Hundi Ganesh Kamath , Sukumar D 
Published: May 2023

Background:
The skin and central nervous system are derivatives of embryonic ectoderm. There is an etiological factor of stressful life events in various skin diseases such as chronic urticaria through psychosomatic mechanisms. Many observations and case series are reported in favor of this opinion.

Objectives:
To evaluate the stressful life events within one year, six months and a month preceding onset or exacerbation of lesions in chronic idiopathic urticaria cases enrolled in this study.

Material and Methods:
It is an Observational descriptive questionnaire-based study, which included minimum of 50 patients of chronic idiopathic urticaria and important stressful events were noted in these subjects using Gurmeet Singh's presumptive stressful life events (PSLE) scale.

Results:
Out of 50 cases, stressful life events preceded the exacerbation of the chronic urticaria in 16 (32%) patients. Amongst them 12 (24%) showed slight degree and four (8%) showed moderate degree of stress and none of the cases reported great degree of stress. Among 16 cases, eight (50%) cases noticed exacerbation within six months of experiencing stressful life event with higher degree of severity in older age group (p = 0.004). Financial loss or problem was the most common stressful life event seen in four out of 16 cases (25%) (p = 0.000). Few desirable events were also found as stressors in four cases accounting for 25%.

Conclusion:
These results support association between psychological factors and exacerbation of the disease. The need for stress management programs in high stress scores to cope up with the stressful events, will further help in reducing the morbidity.
Importance of Dermoscopy in Differentiating Common Urticaria and Urticarial Vasculitis
Authors: Madarkar Mahajabeen Saheb Patel 
Published: May 2023

Background:
Urticarial vasculitis is a clinicopathological entity that overlaps with common urticaria, and histopathological diagnosis is required for differentiation between them.

Objectives:
To determine, for the first time, if skin surface microscopy can aid in the clinical differentiation between common urticaria and urticarial vasculitis in daily practice. Materials and Methods: Lesions in 20 patients with a clinical diagnosis of urticaria were studied. All urticarial lesions were subjected to dermoscopy, skin biopsy, and histopathological examination to confirm the diagnosis. Dermoscopy was performed using Derm Lite 3 dermoscope and images captured were anyalysed. Clinical images were taken. A punch biopsy was performed in all patients. Statistical analysis was done. Results: In 11 patients diagnosed clinically as chronic urticaria, on dermoscopy showed red lines in 9(45%), red dots in 2 (10%) and structureless areas in 8(40%) patients. In 9 patients diagnosed as urticarial vasculitis clinically, on dermoscopy revealed purpuric dots in 8(40%) and purpuric globules in 5(25%) patients.

Conclusion:
We conclude that in our setting dermoscopy significantly facilitates the detection, diagnosis and differentiation of common urticaria and urticarial vasculitis.
BIBLIOMETRIC ANALYSIS OF DISSERTATION RESEARCH IN MANAGEMENT
Authors: Shah Zubair 
Published: May 2023

The purpose of this exploratory and descriptive research is to evaluate a representative sample of reference lists of the selected dissertation research in the field of Management in Pakistan by using descriptive citation analysis methods, citation patterns and citation evaluation on a modified, validated objective Tunon & Brydges rubric. Furthermore, the sample was divided into two lusters to compare mean impact factors of reference lists of two lusters to see if quality of dissertations in Management in general is improving over time. Another comparison is made to see how does the quality of theses completed at public universities fare in comparison to the quality of theses completed at private universities.
The findings of the research show that PhD theses in the field of Management appear to have been improving in terms of quality as total mean impact factor of the theses completed in second luster (2013-2017) was statistically speaking significantly different from that of the first luster (2008-2012). However, no statistically significant difference was noted between total impact factor mean of public universities’ reference lists, when it was compared to that of private universities; allowing the researcher to conclude though quality of PhD thesis have been improving for the 10-year period studied, however there was no qualitative difference between theses completed at private universities and those which were completed at the public universities.
Implementation of School Culture-Based Character Education Strengthening Program at SMP Negeri 10 Satap Tondano
Authors: Mangare Alfando Cester , Langkai Jeane Elisabeth , Tuerah Paulus Robert 
Published: May 2023

This study aims to analyze the implementation of the school culture-based Character Education Strengthening (PPK) program at SMP Negeri 10 Satap Tondano. This research uses a qualitative approach. Data collection in this study was carried out using in-depth interviews, observations, and documentation studies. The results of this study show that the implementation of the school culture-based Character Education Strengthening Program (PPK) at SMP Negeri 10 Satap Tondano has not been implemented optimally due to: 1) the availability of inadequate school facilities and infrastructure to support extracurricular and co-curricular activities which are mandatory components in the implementation of school culture-based KDP, 2) parental support for the child's education process that is still lacking, and 3) inadequate school financing in financing the implementation of activities and the procurement of school facilities and infrastructure. For this reason, we should: 1) schools need to coordinate with all stakeholders in the field of education, 2) the government needs to provide sufficient funds to support the implementation of school-based KDP, 3) need maximum support from parents in the form of attention and supervision of children's associations.
Миллий-маънавий тарбиянинг ўзбек оиласидаги тарихий илдизлари хусусида
Authors: Ақчаев Фаррух , Шералиев Жамшиджон 
Published: May 2023

Мазкур мақолада муаллифнинг ўзбек оиласидаги миллий-маънавий тарбиянинг тарихий илдизлари хусусида фикр-мулоҳазалари баён қилинган. Хусусан, унда миллий-маънавий тарбиянинг муайян услублари, оилада болаларни маънавий-ахлоқий тарбиялашда катталарнинг, ота- оналарнинг ибрати миллий қадрият сифатида катта тарбиявий аҳамиятга эга эканлиги ҳақида сўз юритилади.
Gambaran Kesehatan Jiwa Mahasiswa Keperawatan Pasca Pandemi COVID-19
Authors: Subagyo Widyo , Wahyuningsih Dyah , Mukhadiono Mukhadiono 
Published: May 2023

Background: The COVID-19 pandemic has had a major impact on mental health, including students. Symptoms that are quite dominant include not being able to think clearly, often feeling headaches, not sleeping well, easily feeling afraid, shaking hands, difficulty making decisions, easily tired and others. Students with mental health disorders are at risk of experiencing academic problems. Purpose: This study was to describe the mental health of nursing students after the Covid-19 pandemic. Method: The research design used is descriptive analytic with a cross sectional approach, which is a type of research where the measurement of the variables is only done once at a time. The research instrument for measuring students' mental health uses the Self-Report Questionnaire-20 (SRQ-20). The research population is level 1 nursing students in Purwokerto Nursing Study Program for the 2022/2023 academic year with a total of 133 students. The sampling technique used is total sampling. Result; Respondents on average were 18 years old, mostly female, 117 people (88.00%), owned computer equipment, mostly owned by 98 people (73.70%), parents' income was mostly around Rp. 2 million - Rp. 4 million, namely 65 people (48.90%) and experiencing distress, namely 70 people (52.60%). Conclusion; most nursing students after the Covid-19 pandemic experienced distress.
IVA plädiert für Smart Farming
Authors: Schaal René 
Published: May 2023

Frankfurt a.M. Der Umbau der Landwirtschaft zu mehr Nachhaltigkeit wird nur gelingen, wenn die Politik Innovationen wie Biologicals, Grünes Ammoniak, Digitalisierung und Präzisionslandwirtschaft konsequenter fördert. Das war eine der zentralen Aussagen auf der diesjährigen Jahrespressekonferenz des Industrieverbands Agrar (IVA).
FEATURES OF THE FORMATION OF LANDSCAPE AND NATURAL COMPLEXES IN THE INDUSTRIAL CITIES OF THE PRE-URALS
Authors: Тагирова О.В. , Уразгильдин Р.В. , Гиниятуллин Р.Х. , Янбаев Ю.А. , Кулагин А.Ю. 
Published: May 2023

Показано, что освоение территорий расположения Уфимского и Стерлитамакского промышленных центров в 1850–2020 гг. сопровождалось масштабной вырубкой лесов. При этом часть из них была сохранена, а с 50-х годов ХХ в. успешно реализована программа по созданию санитарно-защитных насаждений. Развитие и увеличение площади городов и формирование ландшафтно-природных комплексов промышленных центров происходит за счет освоения лесных территорий и сельскохозяйственных земель. Современное состояние лесных насаждений Уфимского и Стерлитамакского промышленных центров оценивается как удовлетворительное. Однако культуры тополя Populus balsamifera L. (лесные культуры созданы в 40 – 50-х годах ХХ в.) вступают в критический возраст, и в настоящее время требуются проведение массовых вырубок и реконструкция данных насаждений. Проведение лесохозяйственных мероприятий должно основываться на инвен- таризации состояния лесных насаждений и обосновании и проведении реконструкции насаждений на территории промышленного центра в целях выполнения экологических функций.
It is shown that the development of the territories of the location of the Ufa and Sterlitamak industrial centers for the period 1850–2020 was accompanied by large-scale deforestation. At the same time, part of the forests was preserved, and since the 1950s, a program has been successfully implemented to create sanitary-protective plantations. The development and increase in the area of cities and the formation of landscape-natural complexes of industrial centers occurs due to the development of forest territories and agricultural lands. The current state of forest plantations in the Ufa and Sterlitamak industrial centers is assessed as satisfactory. However, the plantations of a poplar, Populus balsamifera L. (stands were created in the 40–50s of the XX century) are entering a critical age, and mass felling and reconstruction of these plantations is currently required. The implementation of forestry measures should be based on an inventory of the state of stands and their reconstruction on the territory of the industrial center in order to perform ecological functions.
DAMPAK KEPUASAN KERJA TERHADAP KINERJA PADA IBU BEKERJA DITINJAU DARI WORK FAMILY CONFLICT DAN STRES KERJA SELAMA PANDEMIC COVID-19
Authors: Sandini Dwi , Hariyanti Ifani , Maulyan Feti Fatimah 
Published: May 2023

Abstrak-penelitian ini bertujuan untuk menganalisis dampak kepuasan kerja terhadap kinerja ditinjau dari work family conflict dan stress kerja, terutama bagi wanita bekerja dimasa pandemic Covid 19. Perempuan yang telah menikah atau menjadi seorang ibu adalah kelompok yang paling banyak mengalami stres karena menjadi pihak yang paling banyak menanggung beban dan tuntutan selama pemberlakuan sistem kerja dari rumah (WFH) sekaligus juga harus mengurus rumah tangga dan anak yang juga turut belajar dari rumah sehingga akhirnya menyebabkan work family conflict atau konflik peran antara pekerjaan-keluarga. Sample penelitian ini berjumlah 100 orang, Teknik analisis yang digunakan adalah teknik analisis kuantitatif dengan metode regresi linier berganda. Hasil penelitian ini adalah dampak kepuasan kerja memiliki pengaruh yang signifikan terhadap kinerja pada ibu bekerja. Artinya semakin tinggi work family conflict maka akan menyebabkan semakin rendah pula kinerja seseorang, begitu pula sebaliknya.
This study aims to analyze the impact of job satisfaction in terms of work family conflict and work stress, especially for women who work during the Covid 19 pandemic. Women who have worked or become mothers are the group that experiences the most stress due to being the party who the most workloads and workloads during the implementation of the work from home system (WFH) also have to take care of the household and children who also learn from home so that eventually lead to work-family conflicts or role conflicts between work-family. The sample of this research is 100 people. The analysis technique used is quantitative analysis technique with multiple linear regression method. The results of this study are the impact of job satisfaction has a significant influence on the performance of working mothers. This means that the higher the work family conflict, the lower the performance of a person, and vice versa.
PENGGUNAAN LABEL HALAL DAN HARGA DALAM MENINGKATKAN KEPUTUSAN PEMBELIAN PRODUK KOSMETIK (STUDI PADA MASYARAKAT KOTA BANDUNG)
Authors: Nurdin Sahidillah , Setiani Pika Nilam Cahya 
Published: May 2023

Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan label halal dan harga dalam meningkatkan keputusan pembelian produk kosmetik wardah. Populasi yang digunakan pada penelitian ini adalah konsumen yang pernah membeli dan menggunakan kosmetik dengan merek wardah yang berjumlah 97 responden. Metode dalam penelitian ini yaitu menggunakan metode kuantitatif, pengambilan sampel menggunakan teknik non-probability sampling, dimana pemilihan anggota populasi menggunakan purposive sampling, Metode analisis yang digunakan adalah regresi linear berganda dengan bantuan alat olah data statistic SPSS. Hasil penelitian menunjukkan bahwa penggunaan label halal pada kemasarn serta harga secara bersama-sama berpengaruh signifikan terhadap keputusan pembelian dengan arah positif.
PENINGKATAN LOYALITAS PELANGGAN PADA HARIAN UMUM PIKIRAN RAKYAT MELALUI DIGITAL MARKETING DAN CITRA MEREK
Authors: Erika Tsya , Solihat Ani , Trijumansyah Andry , Djunarto  , Scorita Kurnia Budhy 
Published: May 2023

Era globalisasi ini hampir merubah bentuk penyajian media informasi, informasi pada masa kini disajikan tidak hanya dalam bentuk tercetak namun disajikan juga dalam berbagai media atau bentuk elektronik yang dapat di akses melalui jaringan internet. Sampai saat ini zaman konvensional telah berubah menjadi digital yang mengakibatkan loyalitas pelanggan pada media cetak menurun dan persaingan dalam internet meningkat. Tujuan dari penelitian ini untuk mengetahui seberapa besar pengaruh Digital Marketing dan Citra Merek terhadap Loyalitas Pelanggan pada Harian Umum Pikiran Rakyat. Metode penelitian yang digunakan dalam penelitian ini adalah Kuantitatif Deskriptif dan Verifikatif, dengan jumlah responden 100 dan menggunakan teknik sampling insidental. Adapun teknik pengambilan data berupa observasi,, kuesioner, studi kepustakaan dan data primer. Hasil penelitian ini secara parsial digital marketing berpengaruh signifikan terhadap loyalitas pelanggan dan citra merek berpengaruh signifikan terhadap loyalitas pelanggan. Secara simultan digital marketing dan citra merek berpengaruh terhadap loyalitas pelanggan Harian Umum Pikiran Rakyat.
Pengaruh Kegiatan Ekspor Pada Beberapa Pelabuhan Muat Terhadap Penyerapan Tenaga Kerja Di Provinsi Kalimantan Tengah
Authors: Siang. I.S  
Published: May 2023

Penelitian ini bertujuan untuk mengetahui pengaruh Nilai Ekspor dilihat dari beberapa pelabuhan muat secara parsial dan simultan terhadap Penyerapan Tenaga Kerja di Provinsi Kalimantan Tengah. Jenis penelitian explanatory research. sumber data BPS Provinsi Kalimantan Tengah, Bappeda, Kemenperindag, Kementerian Perhubungan/ Komunikasi, dan lain-lain yang terkait. Berdasarkan hasil analisis Regresi Linier Berganda Model Double Logarithma diperoleh hasil analisis yang dapat disimpulkan yaitu : 1. Secara parsial Nilai Ekspor melalui Pelabuhan Muat di Pelabuhan Kumai, Sampit dan Pangkalan Bun mempunyai pengaruh yang signifikan dan positif terhadap Penyerapan Tenaga Kerja di Provinsi Kalimantan Tengah, sementara itu Nilai Ekspor melalui Pelabuhan Muat Pulang Pisau tidak berpengaruh tetapi positif terhadap Penyerapan Tenaga Kerja di Provinsi Kalimantan Tengah. 2. Secara simultan Nilai Ekspor melalui Pelabuhan Muat di Pelabuhan Kumai Sampit, Pulang Pisau dan Pangkalan Bun mempunyai pengaruh yang signifikan terhadap Penyerapan Tenaga Kerja di Provinsi Kalimantan Tengah.
RANCANG BANGUN SISTEM PENGENDALIAN DAN MONITORING PADA LEVEL TANGKI BERBASIS PLC DENGAN MEMBANDINGKAN METODE TUNING COHEN-COON DAN ZIEGLER-NICHOLS
Authors: Darmawan Sutan Alif , Adi Wasis Waskitto , Sahrin Alfin 
Published: May 2023

Sistem kontrol merupakan salah satu elemen yang penting dalam dunia industri khususnya minyak dan gas. Sistem kontrol memiliki fungsi untuk mengendalikan variable proses supaya sesuai dengan nilai yang dikehendaki guna menghasilkan produk yang memiliki mutu tinggi sesuai dengan spesifikasi. Pengendalian level merupakan salah satu variable yang sering dikendalikan, dalam pengaplikasiannya level air harus tetap dijaga agar tidak terjadi kekosongan ataupun melebihi kapasitas. Komponen utama yang digunakan dalam pengendalian prototipe pengendalian dan monitoring level tangki adalah PLC Outseal sebagai controller, sensor submersible water level yang digunakan sebagai sensing element, dan servo valve sebagai final element. Haiwell cloud SCADA digunakan sebagai human machine interface (HMI) yang digunakan untuk memonitoring dan pengendalian serta pengambilan data dari proses prototipe. Pada prototipe ini menggunakan PI controller yang dicari menggunakan dua metode yaitu ziegler-nichols dan cohen-coon yang kemudian respon dari sistem akan dibandingkan guna mendapatkan respon terbaik untuk protitipe. Pada metode ZN didapatkan nilai Kp = 28.03, Ki = 0.32. dan metode CC didapatkan nilai Kp = 89.03, Ki = 1.06, Berdasarkan hasil tuning yang telah dilakukan kedua metode sama-sama tidak memiliki error steady state. Metode CC memiliki respon yang sedikit lebih cepat dibandigkan dengan ZN, tetapi pergerakan MV pada metode CC lebih besar dibandingkan dengan ZN, oleh karena itu metode ZN dinilai lebih cocok digunakan pada prototipe. Selanjutnya dilakukan fine tuning untuk mendapatkan nilai respon yang lebih baik dari metode ZN dan didapatkan nilai Kp 58.5 dan Ki 0.01. Lalu diaplikasikan pada plant dan terbukti mendapatkan respon yang lebih baik.
Validity of B-Mode Ultrasound for Body Composition Assessment in the Field
Authors: Draper Shane , Dearden Conner , Jensen Nate , Holmes Brett , Creer Andrew 
Published: May 2023

Introduction: Identifying an accurate, user friendly alternative to skinfold calipers may allow for accurate assessment of body composition in more applied settings, such as various training and competition venues. The purpose of our study was to determine the validity of B-mode ultrasound (BMUS) for body composition assessment by comparing this method to values obtained using air displacement plethysmography (ADP).
Methods: Twenty-four active runners underwent two forms of body composition assessment during a single lab visit; ADP and BMUS. ADP body density was estimated using an air displacement chamber in combination with measured lung volume. BMUS body density was estimated from measuring the Jackson-Pollock 7 site skinfolds with a portable, app-based ultrasound device to determine subcutaneous fat thickness. Images were analyzed using proprietary software. Body density values for both methods were converted to body fat percentage using the Siri equation. A paired samples t-test was used to compare values obtained from ADP and BMUS.
Results: There was no difference between ADP (18.3 ± 7.3%) and BMUS (17.2 ± 7.6%; p = 0.1) for percent body fat.
Conclusions: BMUS provides a valid method for assessing body composition when compared to ADP, thus providing a portable, accurate method for assessing body composition in applied settings.
PEMBERDAYAAN MASYARAKAT HONAI LAMA II MELALUI PELATIHAN BUDIDAYA PERTANIAN SECARA VERTIKULTUR
Authors: Mahanani Anti Uni , Tuwo Meiky 
Published: May 2023

Lahan pertanian semakin hari semakin sempit karena banyak digunakan untuk pembangunan perumahan dan lain sebagainya. Salah satu cara untuk mengatasi lahan pertanian yang semakin berkurang adalah dengan teknik budidaya vertikultur. Disamping itu, kegiatan ini mempunyai tujuan memperkenalkan dan memberikan pengetahuan tambahan kepada masyarakat di Wamena khususnya di Kampung Honai Lamai II tentang peningkatan produktivitas tanaman melalui teknik budidaya secara vertikultur. Keberhasilan dari kegiatan ini terlihat dari aktivitas dan antusias masyarakat dalam kegiatan pemberdayaan ini disamping juga dari beberapa pertanyaan yang dilontarkan oleh peserta kegiatan