bluuebunny/crossref_metadata_2025_split huggingface dataset:
Call Me by MY Name
Authors: Vũ Kính T. 
Published: August 2023

Abstract
What does care in music education look like when band directors make efforts to know their student musicians (who), beyond ensemble repertoire selections (what)? This narrative about two high school band directors explores teachers’ desires to reach beyond repertoire selection in an effort to know the Asian or Asian American students who participate in their concert and marching band programs. Particular attention is given to how these teachers have developed awareness of their Asian students’ names, and how that awareness aligns with intercultural sensitivity. Participants agreed that it is vital to know students’ names as a form of intercultural sensitivity whereby all learners are recognized and visible as human beings, not viewed merely as sonic contributors to band ensemble sound.
Caring About Deaf Music in Culturally Responsive Music Education
Authors: Churchill Warren N. , Hall Clare 
Published: August 2023

Abstract
This chapter considers the question of how we might be more critically reflexive about an ethic of care between music educators and Deaf people in educational contexts. The authors trouble deficit views of deafness (as a medical condition) that may elicit forms of caring responses based on remediation and compensatory measures. However, in light of the recent proliferation of music-making originating from within the Deaf community, the authors advocate for rethinking care in terms of community rather than deficit. The authors offer an analysis of a Deaf Camp video, which promotes a model of what care can look like in the Deaf community. Noddings’s feminist approach to care, coupled with Hess’s critical scholarship on cultural competence provide a rich theoretical framework to examine tensions that can arise when being inclusive of Deaf students in music education.
Non-Fungible Tokens and Nonprofit Management
Authors: Nolin Heather R. , Whitaker Amy C. 
Published: August 2023

Abstract
While most influential in art markets, the non-fungible token (NFT) phenomenon also has serious ramifications for museums and other cultural institutions. This chapter explores these applications to core nonprofit missions and activities, including audience development, fundraising, earned-income generation, acquisitions, and institutions’ relationships with their communities. Any initiative involving NFTs at a museum is also an exercise in strategic planning. We develop a novel conceptual framework around mapping institutions’ financial and philosophical priorities to guide strategic planning around NFTs. We present this framework through five case studies that range from existing museum projects around revenue generation, conservation, and endowment to two hypothetical scenarios around deaccessioning, restitution, and institutions’ relationships with their audiences. Cultural institutions apart from museums may also find the framework valuable and worth incorporating into their strategic planning processes, as it can be tailored to an organization’s individual priorities, artistic missions, and financial needs.
Putting a price on healthy eating: public perceptions of the need for further food pricing policies in the UK
Authors: Watts Simon , Lloyd-Williams Ffion , Bromley Helen , Capewell Simon 
Published: August 2023

Abstract

Background
Understand factors that influence food choice and explore public perceptions of the need for government policies to improve diets in the UK, particularly food pricing interventions.

Methods
A qualitative study design was used with semi-structured interviews. The study was carried out in Greater Manchester, England. In all, 15 participants from a diverse range of backgrounds were recruited.

Results
Food price, lack of time, availability, and food knowledge and culture were key factors that led some study participants towards unhealthy food choices. The UK’s individual, willpower-focused approach to tackling obesity was deemed ineffective and many participants supported further government intervention. Product reformulation was supported as a less intrusive and less regressive way of improving diets than taxation. There was also support for increasing cooking classes within schools.

Conclusions
Whilst the government ambition to half childhood obesity by 2030 is welcome, population level interventions that enable healthier food choices are needed to achieve this goal. Rising global food prices may make reformulation a more practical policy option than further pricing interventions. Mandatory reformulation of convenience meal and snack products and strengthening education in schools may represent a publicly acceptable and effective package of interventions within a comprehensive strategy to tackle obesity.
Dental eruption and adult dentition of the enigmatic ptolemaiid Qarunavus meyeri from the Oligocene of the Fayum Depression (Egypt) revealed by micro-computed tomography clarifies its phylogenetic position
Authors: Kampouridis Panagiotis , Hartung Josephina , Augustin Felix J , El Atfy Haytham , Ferreira Gabriel S 
Published: August 2023

Abstract
The Palaeogene is a very important time period for mammalian evolution because it documents the first occurrence of many groups. One such group is the enigmatic Ptolemaiida, best known from the Early Oligocene of the Fayum Depression in Egypt, where it is represented by three genera, Ptolemaia, Qarunavus, and Cleopatrodon, including five species. Among these, Qarunavus meyeri is especially rare, as it is only known from two partial juvenile mandibles. Herein, the affinities of this taxon are re-investigated by applying micro-computed tomography (μCT), thus enabling the study and comparison of its unerupted permanent dentition with that of other ptolemaiidans. The μCT analysis confirms that Q. meyeri is a valid species, distinct from all other ptolemaiidans. Both the comparison and a phylogenetic analysis suggest a closer relationship of Qarunavus to the genus Cleopatrodon than to Ptolemaia; thereby, placing Qarunavus in the family Ptolemaiidae. Furthermore, the μCT analysis enabled the assessment of the dental morphology of Q. meyeri revealing an unusual combination of traits, such as a very small single incisor next to a large canine. The eruption sequence of the permanent dentition in Q. meyeri implies a late dental eruption for the species, which would support the hypothesis of Ptolemaiida belonging to Afrotheria.
Association Between Neighborhood Deprivation and Child Cognition in Clinically Referred Youth
Authors: Kalb Luther , Lieb Rebecca , Ludwig Natasha , Peterson Rachel , Pritchard Alison , Ng Rowena , Wexler Danielle , Jacobson Lisa 
Published: August 2023

Abstract:

Objective:
When socioeconomic status is measured at the individual and/or family level, it has long been associated with cognition in children. However, the association between neighborhood deprivation, an index of community-level socioeconomic status, and child cognition is not fully understood. The goal of this study was to investigate (1) the relationship between neighborhood deprivation and child cognitive functioning and (2) whether child age moderates the relationship between cognitive functioning and neighborhood deprivation.

Methods:
This study included 9878 children, ages 3 through 17 years (M = 10.4 yrs, SD = 3.4 yrs). Data were gathered from children referred for and evaluated at an urban, outpatient neuropsychology assessment clinic between 2006 and 2022, located in the Mid-Atlantic region of the United States. Neighborhood socioeconomic status was measured at the census block level using the Area Deprivation Index composite.

Results:
There was a 20-point median difference in overall intelligence between the neighborhoods with the lowest and highest levels of deprivation. Overall intelligence and verbal comprehension, compared with working memory, fluid reasoning, and processing speed, demonstrated the strongest negative association with neighborhood deprivation (all p < 0.05). Older children had lower overall intelligence scores compared with younger children in neighborhoods with high levels of deprivation (p < 0.01), suggesting a cumulative influence of poverty exposure.

Conclusion:
This study demonstrates the stark disparities in child cognitive functioning across levels of neighborhood deprivation. Findings support the importance of access to early interventions and services that promote intellectual growth and verbal capacity among children who live in neighborhoods with great deprivation.
Factors Associated with No-Show Rates in a Pediatric Audiology Clinic
Authors: Adkins David , Rojas-Ramirez Marcia V. , Shanker Anita , Burruss Clayton P. , Mirsky Becky , Westgate Philip , Shinn Jennifer B. , Bush Matthew L. 
Published: August 2023

Objective
To evaluate factors associated with no-show rates in a pediatric audiology clinic.

Study Design
Retrospective review.

Setting
Tertiary referral center.

Participants
All pediatric patients younger than 18 years whose parents/guardians scheduled an appointment at a tertiary Audiology Clinic between June 1, 2015, and July 1, 2017.

Main Outcome Measure(s)
Data included whether the patient came to their appointment, patient age, sex, race, insurance type, appointment type, location, season of appointment, and day of the week of the appointment.

Results
Of the 7,784 pediatric appointments scheduled with audiology, the overall no-show rate was 24.3% (n = 1893). Lower age was significantly associated with no-shows (p = 0.0003). Black/African American children were more likely to no-show compared with White/Caucasians (p = 0.0001). Compared with self-pay/military/other insurance, those with Medicaid were more likely to no-show (p = 0.0001). The highest rate of no-shows occurred during summer (27%). On multivariate analysis, younger age, Black/African American race, and Medicaid insurance were associated with increased no-show rates.

Conclusion
A variety of factors influence no-show rates in a pediatric audiology setting. No-shows can affect treatment quality and affect overall hearing outcomes. Further investigation is necessary to assess barriers to appointment adherence and to develop interventions to improve adherence and care.
Incidence of Otalgia After Orthognathic Surgery
Authors: Sakamoto Yoshiaki , Wakabayashi Kenichiro , Ishii Takenobu , Kishi Kazuo 
Published: August 2023

Background:
In orthognathic surgery, it is well known that maxillary osteotomies and displacements sometimes affect auditory function. Thus, this study examined the relationship between the direction of maxillary displacement and postoperative otalgia.

Methods:
Twenty consecutive patients underwent Le Fort I maxillary osteotomy using advancement, impaction, setback, or a combination of these procedures. The direction of movement and incidence of otalgia were investigated. Patients provided informed consent preoperatively, and postoperative reassurance was prudent.

Results:
Pure-tone average evaluation based on horizontal or vertical movements did not show significant differences, although vertical movements resulted in fewer changes in the hearing threshold. Specifically, no significant changes were observed in the hearing thresholds of patients after surgery. No significant difference was also observed between horizontal and vertical movements in the tympanometry results. Negative changes were found in the results of the Eustachian tube dysfunction test in vertical movements, which returned to preoperative values in the final test.

Conclusions:
The risk of minor changes in hearing function is probable during the first week after orthognathic surgery; however, these negative changes either completely disappear or remain negligible.
Longitudinal Profiling of the Intestinal Microbiome in Children with Cystic Fibrosis Treated with Elexacaftor-Tezacaftor-Ivacaftor
Authors: Reasoner Seth A. , Bernard Rachel , Waalkes Adam , Penewit Kelsi , Lewis Janessa , Sokolow Andrew G. , Brown Rebekah F. , Edwards Kathryn M. , Salipante Stephen J. , Hadjifrangiskou Maria , Nicholson Maribeth R. 
Published: August 2023

ABSTRACTThe intestinal microbiome influences growth and disease progression in children with cystic fibrosis (CF). Elexacaftor-tezacaftor-ivacaftor (ELX/TEZ/IVA), the newest pharmaceutical modulator for CF, restores function of the pathogenic mutated CFTR channel. We performed a single-center longitudinal analysis of the effect of ELX/TEZ/IVA on the intestinal microbiome, intestinal inflammation, and clinical parameters in children with CF. Following ELX/TEZ/IVA, children with CF had significant improvements in BMI, ppFEV1and required fewer antibiotics for respiratory infections. Intestinal microbiome diversity increased following ELX/TEZ/IVA coupled with a decrease in the intestinal carriage ofStaphylococcus aureus, the predominant respiratory pathogen in children with CF. There was a reduced abundance of microbiome-encoded antibiotic-resistance genes. Microbial pathways for aerobic respiration were reduced after ELX/TEZ/IVA. The abundance of microbial acid tolerance genes was reduced, indicating microbial adaptation to increased CFTR function. In all, this study represents the first comprehensive analysis of the intestinal microbiome in children with CF receiving ELX/TEZ/IVA.IMPORTANCECystic fibrosis is an autosomal recessive disease with significant gastrointestinal symptoms in addition to pulmonary complications. Prior work has shown that the intestinal microbiome correlates with health outcomes in CF, particularly in children. Recently approved treatments for CF, CFTR modulators, are anticipated to substantially improve the care of patients with CF and extend their lifespans. Here, we study the intestinal microbiome of children with CF before and after the CFTR modulator, ELX/TEZ/IVA. We identify promising improvements in microbiome diversity, reduced measures of intestinal inflammation, and reduced antibiotic resistance genes. We present specific bacterial taxa and protein groups which change following ELX/TEZ/IVA. These results will inform future mechanistic studies to understand the microbial improvements associated with CFTR modulator treatment. This study demonstrates how the microbiome can change in response to a targeted medication that corrects a genetic disease.
The predictive and prognostic value of peripheral blood antigen-specific memory B cells in phospholipase A2 receptor-associated membranous nephropathy
Authors: Zhu Richard , Tang Hong , Howard Lilian , Waldman Meryl , Zhu Quansheng 
Published: August 2023

AbstractBackgroundPhospholipase A2 receptor-associated membranous nephropathy (PLA2R-MN) is an anti-PLA2R antibody (PLA2R-Ab) mediated autoimmune kidney disease. Although antibody titer correlates closely with disease activity, whether it can provide longer-term predictions on disease course and progression is unclear. Rituximab, a B-cell depletion therapy, has become the first-line treatment option for PLA2R-MN; however, the response to Rituximab varies among patients.MethodsWe developed a flow cytometry-based test that detects and quantifies PLA2R antigen-specific memory B cells (PLA2R-MBCs) in peripheral blood, the primary source for PLA2R-Ab production upon disease relapse. We applied the test to 159 blood samples collected from 28 patients with PLA2R-MN (at diagnosis, during and after immunosuppressive treatment, immunological remission, and relapse) to evaluate the relationship between circulating PLA2R-MBC levels and disease activity.ResultsThe level of PLA2R-MBCs in healthy controls (n=56) is less than or equal to 1.5% of the total MBC compartment. High circulating PLA2R-MBC levels were detected in two patients post-Rituximab despite achieving immunologic and proteinuric remission, as well as in two patients with negative serum autoantibody but increasing proteinuria. Elimination of these cells with Rituximab improved clinical outcomes. Moreover, five patients exhibited elevated PLA2R-MBC levels before disease relapse, followed by a rapid decline to baseline when relapse became clinically evident. COVID-19 vaccination or SARS-CoV-2 infection significantly affected the dynamics of circulating PLA2R-MBCs.ConclusionsThis study suggests that monitoring PLA2R-MBC levels in patients with PLA2R-MN may help refine and individualize immunosuppressive therapy and predict disease course and progression. The technology and findings may also have broader applications in the clinical management of other autoimmune diseases.
Cost-Effectiveness of Systematic Screening and Treatment of Transthyretin Amyloid Cardiomyopathy (ATTR-CM) in Patients with Heart Failure with Preserved Ejection Fraction (HFpEF) in United States
Authors: Lau Anson TC , DiDomenico Robert J. , Kim Kibum 
Published: August 2023

AbstractBackgroundTransthyretin amyloid cardiomyopathy (ATTR-CM) is an underdiagnosed cause of heart failure in clinical practice.99mTc-pyrophosphate scintigraphy (PYP-scan) improves the accuracy of ATTR-CM detection, enabling timely initiation of tafamidis, a drug that slows the progression of ATTR-CM and lowers the risk of adverse cardiac events. We assessed the cost-effectiveness of universal systematic screening (USS) using PYP-scans in patients aged 60 years or older with heart failure with preserved ejection fraction (HFpEF) and ventricular wall thickness of at least 12mm.MethodsTwo screening strategies, USS of ATTR-CM with PYP-scan versus selected clinical referrals for PYP-scan in standard-of-care (SoC), were compared in a model-based assessment. Treatment decisions were based upon the accuracy of each screening strategy, which was followed by Markov state transitions across NYHA functional classes and death. Model inputs were identified from a literature review. We calculated lifetime cost in 2022 US dollars and quality adjusted life-years (QALYs) of each strategy. The primary outcome was the incremental cost-effectiveness ratio (ICER).ResultsThe USS was associated with a significant increase in lifetime costs ($124,380 vs. $70,412) and modest improvement in QALYs (4.42 QALYs vs 4.36 QALYs). The ICER for the USS was $919,509 per QALY gained. ICER was sensitive to the age at the time of ATTR-CM diagnosis, true prevalence rate of ATTR-CM, and daily cost of tafamidis.ConclusionsOwing to the high cost of treatment with tafamidis, USS along with PYP scan for ATTR-CM in older HFpEF patients with ventricular wall thickening is unlikely to become a cost-effective strategy at a liberal WTP threshold.What is Known- ATTR-CM is a rare but serious condition that leads to a restrictive cardiomyopathy with symptoms that mimic heart failure from other causes (e.g., HFpEF).- PYP-scan, when it is used along with the other conventional diagnostic tests, is a non-invasive diagnostic tool that sensitively and specifically detect ATTR-CM followed by a timely treatment with tafamidis.- Tafamidis can slow down ATTR-CM progression and improve survival.What the Study Adds- This is the first attempt to evaluate the cost-effectiveness of universal systematic screening of ATTR-CM using PYP-scans in older HFpEF patients with ventricular wall thickening.- The study found that the universal systematic screening is not cost-effective compared to standard-of-care at a liberal WTP threshold, mainly due to the costly treatment option.- The study identified the key parameters that affect the cost-effectiveness of screening, such as age, prevalence, and drug cost.
Quercetin alleviates intestinal oxidative stress in Jilin White geese
Authors: Yingkun Liu , Wei Guo , Fangyuan Jia , Kai Wang , Zhichao Li , Tao Zhang , Mo Liu , Haizhu Zhou 
Published: August 2023

AbstractOxidative stress can occur during all stages of geese breeding, frequently damaging the intestinal tract and various tissues and organs. Quercetin is a flavonoid that exerts potential therapeutic effects against oxidative stress-induced cell damage and mitochondrial dysfunction. Herein, we investigated the alleviating effects of quercetin against lipopolysaccharide (LPS)-induced intestinal inflammation and oxidative stress in Jilin White geese. We selected 120 healthy male 7-d-old geese of similar BW and randomly divided them into six treatment groups, with five replicates each and four geese in each replicate. The groups were as follows: C (fed basal diet, i.p. injection of 0.5 mg/kg normal saline); L (fed basal diet, i.p. injection of 0.5 mg/kg LPS); Q1, Q2, Q3, and Q4 (diet + 150, 300, 450, or 600 mg/kg quercetin, respectively, i.p. injection of 0.5 mg/kg LPS). Samples were collected after experimental d 21. Our results showed that adding 300 mg/kg quercetin to the diet significantly improved growth performance after oxidative stress and reduced serum low-density lipoprotein and glutathione aminotransferase activities. Adding 450 mg/kg quercetin significantly increased the intestinal expression of downstream genes of the nuclear factor E2-related factor 2 pathway, heme oxygenase 1 (HO-1), reduced coenzyme/quinone oxidoreductase (NQO1), and glutathione oxidase (GSTP) in Jilin White geese. Considering production, adding 300 mg/kg quercetin to the diet could alleviate LPS-induced oxidative stress and reduce costs. These findings provide a reference hypothesis for the oxidative stress damage during geese production, which may help reduce the economic loss owing to geese mortality.
Stable recurrent dynamics in heterogeneous neuromorphic computing systems using excitatory and inhibitory plasticity
Authors: Maryada  , Soldado-Magraner Saray , Sorbaro Martino , Laje Rodrigo , Buonomano Dean V. , Indiveri Giacomo 
Published: August 2023

AbstractMany neural computations emerge from self-sustained patterns of activity in recurrent neural circuits, which rely on balanced excitation and inhibition. Neuromorphic electronic circuits that use the physics of silicon to emulate neuronal dynamics represent a promising approach for implementing the brain’s computational primitives, including self-sustained neural activity. However, achieving the same robustness of biological networks in neuromorphic computing systems remains a challenge, due to the high degree of heterogeneity and variability of their analog components.Inspired by the strategies used by real cortical networks, we apply a biologically-plausible cross-homeostatic learning rule to balance excitation and inhibition in neuromorphic implementations of spiking recurrent neural networks. We demonstrate how this learning rule allows the neuromorphic system to work in the presence of device mismatch and to autonomously tune the spiking network to produce robust, self-sustained, fixed-point attractor dynamics with irregular spiking in an inhibition-stabilized regime. We show that this rule can implement multiple, coexisting stable memories, with emergent soft-winner-take-all (sWTA) dynamics, and reproduce the so-called “paradoxical effect” widely observed in cortical circuits. In addition to validating neuroscience models on a substrate that shares many similar properties and limitations with biological systems, this work enables the construction of ultra-low power, mixed-signal neuromorphic technologies that can be automatically configured to compute reliably, despite the large on-chip and chip-to-chip variability of their analog components.