bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors Associated with Receptive and Expressive Language in Autistic Children and Siblings: A systematic review
Authors: Mues Marjolein , Schaubroeck Sarah , Demurie Ellen , Roeyers Herbert 
Published: April 2023

Abstract

Background
Language abilities of autistic children and children at elevated likelihood for autism (EL-siblings) are highly heterogeneous, and many of them develop language deficits. It is as of yet unclear why language abilities of autistic children and EL-siblings vary, although an interaction of multiple influential factors is likely at play. In this review, we describe research articles that identify one or multiple of such factors associated with the receptive or expressive language abilities of autistic children and EL-siblings since the introduction of the DSM-5.
Aims
Our aim was to identify and summarize factors that are linked to language development in autistic children and siblings in the recent literature to ultimately gain insight into the heterogeneity of language abilities in these children.
Method
The search strategy of this review followed the PRISMA guidelines. The following databases were consulted: Embase, MEDLINE, Web of Science Core Collection and Scopus. Inclusion criteria for studies were the presence of a sample of autistic children no older than seven years old who were diagnosed with autism spectrum disorder per the criteria of the DSM-5. Intervention studies and studies without an explicitly reported language measure were excluded. Risk of bias assessment was completed using the Newcastle-Ottawa Scales. Ultimately 54 articles were included in this review.
Results
56 factors were identified to be related to receptive or expressive language abilities of autistic children and EL-siblings. They were grouped into three main categories: biological factors; psychosocial and environmental factors; and age-related and developmental factors, each with different subcategories. Although many of the identified variables were only examined in one article, some well-researched associated factors stood out, in particular joint attention, nonverbal cognitive abilities and frontal EEG power. Better insight in these factors shaping language abilities in autistic children and siblings at elevated likelihood can inform future intervention strategies to reduce language deficits and its corresponding negative consequences in these children
Conclusions
Our results confirm that multiple different factors likely underlie language deficits in autism. Important aspects that should be considered in such a model are, amongst others, social factors such as joint attention, child characteristics such as nonverbal cognition, and neurocognitive factors.
Associations between Blood Pressure Control and Documented Nutrition Care Using Structured Data from Electronic Health Records of Patients with Hypertension
Authors: Williams April , Britton Erin L , Thomson Maria D. 
Published: April 2023

Abstract
Background Documentation in Electronic Health Records (EHRs) of nutrition care events (overweight or obesity (BMI > 25 or 30, respectively) diagnoses, preventive care visits, or provision of patient education materials (PEM)) for chronic diseases is unclear.Methods Cross-sectional analysis using structured EHR data from primary care visits at a health system in the US from January 2018 - December 2020 of adult patients with hypertension (n = 6,419) tested for associations between last visit blood pressure (BP) control (≤ 140 Systolic BP and ≤ 90 Diastolic BP) and aggregate nutrition care events. Descriptive statistics and multiple logistic regression models were constructed to examine the predictive power of nutrition care events for blood pressure control.Results The median age was 62 years, 32% were male, 48% were Black, 26% were from rural areas and 35.9% had controlled BP at last visit. For the 62% of patients with documented nutrition care, 14.6% had an overweight/obesity diagnosis, 26.2% had a preventive care visit, and 42% received PEM with dietary and hypertension content. The models showed patients who had more preventive care visits (aOR 1.12; CL 1.06, 1.18) had higher odds for BP control. Whereas Black patients compared with white patients (aOR 0.84; CL 0.74, 0.95), those with more hypertension medications (aOR 0.97; CL 0.96, 0.99) and more primary care visits over the study period (aOR 0.98; CL 0.97, 0.99) had lower odds for BP control.Conclusions In this study, documented nutrition care in preventive care visits is significantly associated with BP control, but documentation is infrequent. Additional research should include examining clinical notes for evidence of nutrition care, which may uncover areas that show promise for improving nutrition care for patients with chronic disease.
Development of a robust TaqMan probe-based one-step multiplex RT-qPCR for Simultaneous detection of SARS-CoV-2 and influenza A/B viruses
Authors: Abbasi Hamidreza , Nikoo Hadi Razavi , Fotouhi Fatemeh , Khosravi Ayyoob 
Published: April 2023

Abstract
Background: During the coronavirus disease 2019 (COVID-19) pandemic, the simultaneous detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza A/B viruses are essential in the rapid differential diagnosis in patients with similar symptoms. So far, several multiplex methods were published for simultaneous detection of SARS-CoV-2 and Flu A/B. However, due to the rapid mutation rate of the SARS-CoV-2 genome and the emergence of new variants, making it necessary to improve and update existing methods.
Methods: To identify a highly conserved region on SARS-CoV-2 N-gene, variant genome survey was performed to increase the sensitivity and specificity of primers and probe annealing to the SARS-CoV-2 genome. The analytical and diagnostic sensitivity and specificity of our multiplex RT-qPCR assay were determined; and the kappa agreement was calculated to highlight the agreement using the Chi-square test by SPSS 22.0.
Results: The new set of SARS-CoV-2 primer-probes designed in the present assay was able to detect all variants of concern (VOCs) and variants of interest (VOIs) with high analytical specificity among other respiratory viruses. The analytical sensitivity by our multiplex assay was ≤ 30 copies of the plasmid per reaction. A total of 70 clinical samples were analyzed using our multiplex assay and compared with multiplex commercial kit. The sensitivity of our multiplex RT-qPCR assay and commercial kit were 95.4% and 93.1%, respectively. Also, the specificity was the same (100%) in both methods. Kappa agreement was measured at 0.97 and 0.90 for our multiplex assay and commercial kit respectively.
Conclusions: A novel and robust TaqMan probe-based one-step multiplex RT-qPCR assay, with high analytical and clinical performance and agreement was developed and validated in this study. It will be valuable in influenza seasons when influenza expected co-circulate with SARS-CoV-2, due to saving costs, time, and consequently, specific and timely treatment of patients.
On the Location of the Nontrivial Zeros of the Riemann Zeta Function on the Critical Line
Authors: Arwashan Naji 
Published: April 2023

Abstract
In this paper we focus our attention on the zeta series ζ (s) = Σ∞n=1 1/ns in the domain of 0 < σ < 1 Even though the series is divergent in that domain, but we will find that its divergence will satisfy an asymptotic equation that involves the values of the zeta function in that same domain. Applying that equation to the critical line will lead us to a function that calculates the value of a convergent series of cosine waves; and interestingly we will find that the finite sum of that series is a combined wave that reorganizes the location of the nontrivial zeros of the Riemann zeta function on the critical line.
MSC code 11E45
Outcomes of incomplete abortion related to treatment modality
Authors: Sharvit Merav , Yagur Yael , Shams Rebecca , Daykan Yair , Klein Zvi , Schonman Ron 
Published: April 2023

Abstract
Purpose: This study evaluated the differences in treatment outcomes between misoprostol and surgical evacuation in the management of incomplete abortion.
Methods: This retrospective cohort study compared patients with clinical diagnosis of incomplete abortion who underwent surgical or pharmacological (misoprostol) intervention, between the years 2014–2017. Demographics, sonographic results, treatment follow-up, and post-intervention data on retained products of conception were retrieved. A comparison was made between women with incomplete abortion who underwent surgical versus pharmacological intervention.
Results: Among 589 spontaneous abortions, 198 were included in the study, of which 123 (62.1%) underwent surgical evacuation, and 75 (37.9%) pharmacological intervention with misoprostol. Baseline characteristics were similar between groups. During 130.8 ±91.7 days of follow-up, no patient who underwent surgical evacuation had retained products of conception or needed surgical hysteroscopy. Four cases (5.3%) in the misoprostol group had retained products of conception and needed hysteroscopy (p=0.02). Patients who underwent surgical evacuation had higher haemoglobin levels during follow-up (12.1 mg/dl vs. 11.7 mg/dl, p=0.05). No differences between groups in post-treatment pregnancy rates.
Conclusion: Long-term follow-up after incomplete abortion showed that hemodynamically stable patients treated with misoprostol achieved the desired results in 95% of cases without any clinical changes in haemoglobin level or pregnancy interval.
On the wake of propeller hydrokinetic turbines: Numerical simulations and experiments
Authors: Macías Marianela Machuca , Mendes Rafael Castilho Faria , Pereira Michael , Dobrev Ivan , Oliveira Taygoara Felamingo , Junior Antonio Cesar Pinho Brasil 
Published: April 2023

Abstract
The objective of this paper is to characterize the wake flow from a high-solidity propeller four-blade horizontal axis rotor commonly used in hydrokinetic turbines. A numerical and experimental study was conducted to describe the turbulent flow in the wake. Velocity flow measurements were obtained using PIV and hot-wire anemometry techniques in two different wind tunnel facilities. CFD simulations were carried out using a 3D full description of the rotating turbine rotor with an unsteady model. Additionally, simulations were conducted using a simplified model that described the rotor as actuator lines. The numerical results and experimental data were compared, and the study achieved good results for estimating machine performance and describing the main vortex structures in the turbine wake.
A novel narnavirus isolated from Colletotrichum curcumae strain 780-2T
Authors: Fu Yujia , Wang Tian , Zhou Siyu , Zhou Jingyi , Zhao Yang , Chen Daipeng , Zheng Li 
Published: April 2023

Abstract
The complete genome of a novel mycovirus, Colletotrichum curcumae narnvirus 1 (CcNV1), derived from the phytopathogenic fungus Colletotrichum curcumae strain 780-2T was sequenced and analyzed. The full sequence of CcNV1 is 3,374 bp in length and contains a single large open reading frame (ORF) encoding an RNA-dependent RNA polymerase (RdRp) of 1,087 amino acids with a molecular mass of 124.2 kDa that shares the closest similarity with that of Monilinia narnavirus H (53.02% identity). RdRp phylogeny analysis showed that CcNV1 is a new member of the genus Betanarnavirus within family Narnaviridae. This is the first report of a novel narnavirus infecting the phytopathogenic fungus C. curcumae, the causal agent of leaf blight of Curcuma wenyujin.
Intensification of alkali catalyzed transesterification of sunflower oil with methanol using rotor pulse cavitator
Authors: Nikolić Ivan , Bubanja Aleksandar R. , Jovanović Jelena D. , Adnađević Borivoj K. 
Published: April 2023

Abstract
Intensification of mass and heat transfer within a chemical reactor is of exceptional scientific and technological importance. Bearing that in mind, in this paper the effect of the following operational parameters of the alkali catalyzed transesterification of sunflower oil with methanol assisted by rotor pulse hydrodynamic cavitation (ACTO) was examined: contact time (tc); methanol to oil molar ratio (M1); concentration of the catalyst (Cc); temperature (T) and the number of passes of the reaction mixture (n) on the triglyceride conversion (TC) and cavitation yield (CY). ACTO was performed by a rotor pulse cavitation reactor (RPC) in single-pass mode. TC was determined by gas chromatography. The results show that already at tc=0.1s and n=1 a high TC=98% is achieved. Increasing the Cc value from Cc=0.3wt% to Cc=0.5wt% leads to an increase in the TC value from TC=0% to TC=98%. An increase in the value of M1 at a value of M1≥3 leads to an increase in the value of TC. An increase in the T of the reaction mixture causes a decrease in the value of TC. The established effect of operational parameters on TC and CY is explained by the influence of the selected operational parameter on the dissipation of kinetic energy in the reaction mixture caused by impulse and cavitation effects.
HIV-Related Knowledge and Health Care Seeking Barriers among Transgender Individuals in Dhaka City: A Cross-sectional Study
Authors: Rahman Md. Mantaka , Alam Ummul Khair , Prabawanti Ciptasari , Shimu Afroza Tamanna 
Published: April 2023

Abstract
Background: The prevalence of HIV among Transgender is 1% while only 0.9% in Dhaka City having one-third times a lifetime higher risk of HIV infection. Being minority group barriers faced by transgenders for healthcare-seeking are major public health concerns. Thus, the study aims to find out the HIV-Related knowledge & Health Care Seeking Barriers among Transgender Individuals in Dhaka City.
Methods: This was a cross-sectional study purposively selecting 135 transgender from Drop-in-center and three Hijra pollis of Dhaka City. Data was collected using a semi-structured questionnaire containing a Likert scale regarding HIV-related knowledge.
Results: Majority were professional sex sellers including 54.1% having irregular sexual clients while 48.9% had been engaged in sex work for more than 10 years. Although more than half (57%) had good HIV-related knowledge. Only one-third (37.3%) sometimes used barrier method and more than half (58%) had knowledge of HIV symptoms. The barriers were negligence (16%), inconvenient location (12.43%), shame (13.45%), judgmental (11.68%), fear (7.6%) and long waiting time (8.1%). Transgenders from Badda DIC had higher HIV-related knowledge compared to ones from hijra pollis [t (95% CI)=.168, p=.000] Those having HIV-related higher knowledge didn’t feel the necessity of isolated health corners [t (95% CI)= -3.799, p= .001]
Conclusion: Although DIC provides healthcare services, but existing facilities barriers need to be addressed to extend health services.
Echocardiographic measurements of left ventricular function in omphalocele with pulmonary hypertension
Authors: Yang Si-Si , Huang Wen-Chang , Wang Peng , Liu Tai-Xiang , Tou Jin-Fa , Gong Fang-Qi , Lai Dengming 
Published: April 2023

Abstract
Purpose: To compare echocardiographic parameters of left ventricular (LV) function in survival and death cohort of omphalocele neonates with pulmonary hypertension (PH), and explore the correlation with neonatal outcomes.
Methods: This retrospective study was conducted among omphalocele patients with PH born from 2019 to 2020. Patients in this study did not have severe malformations or chromosomal aberrations. Patients who died due to the management of palliative care were excluded. Clinical and outcomes data were recorded, echocardiograms evaluated for left ventricular internal diameter diastolic (LVIDd), end-diastolic volume (EDV), stroke volume (SV) and cardiac output index (CI), among others.
Results: There were 18 omphalocele newborns with PH, of whom 14 survived and 4 died. Dead patients were comparable with survivors in the baseline characteristics. LVIDd, EDV, SV and CI were significantly worse in the death group, compared with survival group. These echocardiographic parameters were associated with death outcomes in omphalocele patients with PH.
Conclusion: LV function was significantly impaired in dead omphalocele neonates with PH, when compared with survivors. In the cohort of omphalocele patients with PH, LV dysfunction was associated with mortality.
Level of evidence: Level III
Different contributing processes in bacterial vs. fungal necromass affect soil carbon fractions during the plant residues transformation
Authors: Xue Zhijing , Qu Tingting , Li Xiaoyun , Chen Qin , Zhou Zhengchao , Wang Baorong , Lv XiZhi 
Published: April 2023

Abstract
Aims Recent research has suggested that microbial necromass has a disproportionate influence on soil organic C accumulation. But few field studies have followed the bacterial and fungal necromass vacations during plant residue decomposition.
Methods We investigated in a 512-days culture experiment with a perennial C3 herb (St.B, S. bungeana) to trace the formations of muramic acid (MurA) vs. Glucosamine (GluN), and investigate the relationships between MurA, GluN and soil C fractions.
Results The results showed that the bacteria community dominates the decomposition process due to soil pH (>7) and microbial metabolic C-, P-limitations. The dynamics of MurA changed from fluctuating variations to a significant increase. Bacterial necromass has been in a balance of accumulation and decomposition at early and middle periods. The entombing effect in the later stage resulted in bacterial necromass accumulation. While in the case of microbial metabolism limitation, GluN will lose its physicochemical protection and be degraded. Microorganisms regulate the turnover of POC, MAOC and MBC by microbial biomass and necromass. The utilization of soil C fractions is the direct cause of SOC decline, while microbial necromass only plays an indirect role. The priming effecting caused by one-time input of high C/N ratio plant residues leads to the absence of SOC accumulation in the short term.
Conclusions With the synergistic effect of soil C fractions, the production of microbial biomass and the degradation of cellular residues maintain microbial stoichiometric homeostasis. In addition to soil pH, microbial biomass stoichiometry co-determines microbial necromass formation.
Feasibility of a new clinical journal club implementation and its association with knowledge, attitudes, and application of evidence-based practice among chiropractic students and trainees: a before-and-after healthcare education improvement study
Authors: Häusler Melanie , Lalji Rahim , Hofstetter Léonie , Hincapié Cesar A. 
Published: April 2023

Abstract
Background Evidence-based practice (EBP) is the integration of best research evidence with clinical expertise and patients’ values and preferences. Little is known about knowledge, attitudes, and application of EBP among chiropractic students and trainees. Our aims were to (1) examine the feasibility of implementing a new journal club format within a Swiss university chiropractic healthcare education setting, and (2) assess the associations between the new journal club implementation and EBP characteristics among chiropractic students.Methods A before-and-after study was conducted through a newly implemented journal club with 5th and 6th year chiropractic students and postgraduate trainees between 1 February 2021 and 31 July 2021. The journal club was developed based on the “community of practice” and “team-based learning” conceptual frameworks. EBP knowledge, attitudes, personal application, and future use, were assessed with a validated questionnaire. We summarised participant characteristics using descriptive statistics, estimated before-and-after EBP total and subscale scores (i.e., knowledge, attitudes, personal application, and future use), and conducted an exploratory subgroup analysis based on journal club attendance (Group A: 3–5 and Group B: ≤ 2 sessions attended).Results Among 32 eligible students and trainees, 29 participants (mean age 26 years; 79% women) were enrolled: 25 (78%) responded to the pre- and 29 (91%) to the post-assessment surveys. Most (80%) were chiropractic students and 20% were postgraduate trainees. Group A consisted of 12 (41%) and Group B of 17 (59%) participants, respectively. We found reasonable feasibility for the new journal club format and our findings were compatible with no difference in before-and-after EBP scores (median EBP total score before: 72.6 [IQR, 63.7–77.4], and after: 73.4 [IQR, 61.3–78.2]). Exploratory subgroup analyses based on journal club attendance were consistent with our overall findings.Conclusion Our study suggests that the newly implemented journal club and embedding chiropractic educational research within the journal club were feasible and acceptable. Small before-and-after differences in the EBP subscale scores for knowledge, attitudes, personal application, and future use were observed in chiropractic students and postgraduate trainees. The small study size and short timeframe during a single semester limit potential inferences.
Lymphoscintigraphy findings in patients with chylothorax: influence of biochemical parameters
Authors: Zhang Li , Zhang Xiaoyue , Wen Zhe , Tong Guansheng , Hao Kun , Qiu Yongkang , Kang Lei 
Published: April 2023

Abstract
Background Chylothorax is a condition that can be challenging to diagnose due to its nonspecific clinical presentation. Several biochemical parameters of chylous pleural effusion have been identified as important indicators for the diagnosis of chylothorax. Lymphoscintigraphy, a non-invasive imaging technique, is also used to evaluate chylothorax and determine the location of chyle leakage. This study aimed to evaluate the correlation between the biochemical parameters of chylous pleural effusion and 99mTc-dextran (DX) lymphoscintigraphy in diagnosing chylothorax.
Material and methods A total of 120 patients were enrolled, 83 of the patients had unilateral chylothorax, and 37 had bilateral chylothorax. All patients conducted both 99mTc-DX lymphoscintigraphy and pleural effusion laboratory analysis. The images were classified into positive and negative groups based on whether an abnormal accumulation of the radioactive tracer was observed in the thorax on 99mTc-DX lymphoscintigraphy. And the biochemical parameters of the two groups were compared.
Results Among these patients, 101 (84.17%) had exudative effusions, and 19 (15.83%) had transudative effusions, according to the levels of pleural effusion protein, lactate dehydrogenase and cholesterol. Abnormal tracer accumulation in thorax was observed in 83 patients (69.17%). Exudative and transudative chylothorax are not associated with lymphoscintigraphy results (P = 0.597). In all biochemical parameters, lymphoscintigraphy positive group had significantly higher levels of pleural effusion triglyceride and pleural effusion triglyceride/serum triglyceride ratio compared with negative group (P = 0.000 and P = 0.005). The cutoff values that we identified for pleural effusion triglycerides and pleural effusion triglyceride/serum triglyceride ratio were 2.870 mmol/L and 4.625, respectively, which can facilitate differentiating the positive and negative results on lymphoscintigraphy.
Conclusion Lymphoscintigraphy technique is a reliable diagnostic tool for the qualitative evaluation of chylous pleural effusion. Higher pleural effusion triglyceride level and pleural effusion triglyceride/serum triglyceride ratio indicate a positive result in patients with chylothorax on lymphoscintigraphy, and the cutoff values of 2.870 mmol/L and 4.625 can help with the diagnosis.