bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Novel Framework to Construct Quantum Circuits of S-Boxes: Applications to 4-bit S-boxes
Authors: JEON Yongjin , Baek Seungjun , Kim Jongsung 
Published: March 2023

Abstract
In this paper, we present a new framework to construct a quantum circuit of S-boxes.We first model the quantum circuits of S-boxes based on the Toffoli and linear layers. We generate vector spaces with the values of qubits used in the linear layers and apply them to find quantum circuits.Our technique find the quantum circuit by matching the vector space's elements to the S-box's input and output, based on the meet-in-the-middle strategy.We applied our technique to 4-bit S-boxes.While existing LIGHTER-R tools only find 4-bit S-boxes circuits that can be implemented with 4 qubits, our tool accomplishes the same with 5 qubits.Our tool also finds reversible quantum circuits of 4-bit S-boxes, which are odd permutations that LIGHTER-R cannot.We expect our technique will become an important step towards finding optimized S-box quantum circuits.
Correlates of teenage pregnancy among female secondary school students in Dire Dawa City, East Ethiopia
Authors: Adem Mawerdi , Hailu Saba , Assefa Nega , Assebe Tesfaye 
Published: March 2023

Abstract
Background: Although teenage pregnancy causes a considerable challenge to young women, studies among sexually active teenagers are not widely available. Studies have included both sexually active and not active teenagers in assessing teenage pregnancy which underestimated the actual prevalence. This study aims to determine the prevalence and related factors of teenage pregnancy among teenage girls in dire dawa administrative town, East Ethiopia.
Methodology: Institutional-based cross-sectional study was conducted among 677 identified sexually active students from selected schools. Pre-test was conducted on 35 female teenagers. One stage cluster sampling technique was used to recruit study participants. Data was entered into EpiData-version 3.1 and exported to STATA version 16 for analysis. Modified Poisson regression was done to assess the association between outcome and predictor variables.
Result: Out of the total sexually active females 135 (19.9%) were pregnant. Teenage pregnancy was higher among teenagers in the 18-19 (APR=3.21, 95% CI: 2.10-5.18) age group, living with either of their biological parents (APR=1.9, 95% CI: 1.29-2.69) and neither of the biological parents (APR=2.7 95% CI: 1.39-3.34), teenagers who had sex due to peer pressure (APR=2.01, 95% CI: 1.51- 2.86) and not knowing the ovation time in the menstrual cycle (APR=1.6, 95% CI: 1.07-2.28). Teenage pregnancy was lower among teens who have good parent-daughter interaction (APR=0.6, 95% CI: 0.50- 0.91).
Conclusion: Nearly one-fifth of teenagers had experienced teenage pregnancy. Teenage pregnancy is higher amongst the age group of 18-19, living with either or neither of the parents, having sex due to peer pressure, not knowing the ovulation time in the menstrual cycle, and lower among teens with good parent-daughter interaction. Adolescent sexual and reproductive health education including safe sex practice has to be acknowledged in school and life skill training to enhance self-esteem among teens is essential to reduce teenage pregnancy.
Obesity; Spatial Accessibility and SEIFA Case Study: Greater Melbourne Area (GMA)
Authors: Hatami Yaser , Qadikolaei Mohsen Roohani , Namin Sara Nikmard 
Published: March 2023

Abstract
Today, the inequality of distribution of built environments leads to the formation of advantaged and disadvantaged neighborhoods. Advantage neighborhoods have good accessibility (Distance to) and availability (Number of) service centers. If the neighborhoods have some service centers that don’t provide healthy lifestyles, especially in increasing obesity, they can decline community health in these areas. So, this research tries to have a spatial view of obesity as a dependent variable. Independent variables are the number of and distance to food, smoking, and physical activity centers that are based on theoretical concepts. We analyzed them with dependent variables on SEIFA Clusters at SA2 level. This research has used spatial analysis methods such as BILISA Cluster on Local Moran I for clustering, GWR for spatial correlation which is a base of the analysis method. The results in the Great Melbourne Area (GMA) show that the level of accessibility is more important than availability and some SA2s in the low levels of SEIFA haven’t good access to a healthy built environment and which makes them more obese.
Building Eastern Hellbender (Cryptobranchus a. alleganiensis) Populations through Reintroduction of Head-Started Individuals
Authors: Kaunert Matthew D. , Brown Ryan K. , Spear Stephen , Johantgen Peter B. , Popescu Viorel D. 
Published: March 2023

Abstract
Freshwater biodiversity is declining at a fast pace despite significant efforts directed towards the management and conservation of aquatic systems. Specifically, amphibians are among the most threatened taxa, with loss of aquatic habitat and alteration of habitat quality among important drivers of decline. Eastern Hellbenders are one of North America’s most iconic stream amphibian species, a sentinel of stream health, and are experiencing rapid population declines throughout most of their range. Common conservation strategies include headstarting (raising animals in captivity from wild eggs until 3–4 years old) and releasing them into streams. However, the success of this strategy for rebuilding hellbender populations and the most optimal release scenarios have largely been unassessed. In this study, we use a cohort of 205 headstart animals released in several Ohio watersheds in 2018 to evaluate the success of headstarting and reintroduction efforts over 3 years. Using PIT-tag surveys over 25 occasions between July 2018 and November 2021 and capture-recapture models, we found that 3-year apparent survival post-release was 0.162 ± 0.061, with lower survival in the first year (0.383 ± 0.058) and higher in years 2 (0.696 ± 0.086) and 3 (0.609 ± 0.154). We used demographic simulations integrating survival data from this study and from the literature to evaluate the number of releases and timing of releases required for building self-sustaining populations. We found that, given the low survival post-release, releasing cohorts of N = 100 individuals at fewer suitable sites several times (e.g., 3 releases, 2 or 3 years apart) would be a better strategy to achieve a high number of breeding adults compared to single release events across multiple sites. In addition, Eastern Hellbender headstarting programs using wild eggs are highly beneficial in producing more animals reaching adulthood (up to 7 times) compared to allowing eggs to develop in the wild. This study emphasizes the need to monitor the success of reintroduction programs, particularly for species with cryptic lifestyles. It also provides evidence that headstarting can be a viable strategy for rebuilding Eastern Hellbender populations, particularly if implemented in tandem with other management actions such as improving habitat and water quality and mitigating other threats.
Efficacy of Radiation Plus Transarterial Chemoembolization and Lenvatinib in Hepatocellular Carcinoma With Portal Vein Tumor Thrombus
Authors: Dong Aoran , Zhu Meiyan , Zhang Zeyu , Fan Wenzhe , Wu Zhiqiang , Chen Yong , Tu Jianfei , Zhang Yaojun , Zhuang Wenquan , He Xiaofang , Peng Zhenwei 
Published: March 2023

Abstract
Objective
We aimed to investigate the efficacy of a novel regimen, external beam radiation (RT) combined with transarterial chemoembolization (TACE) and lenvatinib (LEN), in the treatment of hepatocellular carcinoma (HCC) with portal vein tumor thrombus.
Methods
We prospectively observed 102 participants from three tertiary medical centers in China between October 2018 and October 2020, who chose either RT plus TACE and LEN (RT-TACE-LEN) or TACE and LEN (TACE-LEN). LEN (12 mg or 8 mg daily) was administrated orally and continued until progression or intolerable side effects were noted. TACE was given one day after administration of LEN, and RT began within 4 weeks after the first TACE. The median dose/fraction of RT was 50 Gy/25 fractions (range: 45–60 Gy/25 fractions). Overall survival and progression free survival were compared between two groups, and complications were assessed.
Results
Both 51 patients received RT-TACE-LEN and TACE-LEN, respectively. Most patients had tumor size > 5 cm (73.8%) and tumor number ≥ 2 (69.9%). The overall incidence of toxicities was significantly higher in RT-TACE-LEN group than TACE-LEN group (100% vs. 64.7%, p < 0.001), but incidences of grade 3–4 toxicities were comparable (54.9% vs. 49.0%, p = 0.552). Both median overall survival (22.8 vs. 17.1 months, p = 0.031) and median progression-free survival (12.8 vs. 10.5 months, p = 0.035) were significantly longer after RT-TACE-LEN treatment than TACE-LEN.
Conclusions
The addition of RT to TACE and LEN was safe, and might improve clinical outcomes of patients with advanced HCC, which needs conformation from further studies.
CoRBS: A Dynamic Storytelling Algorithm using a Novel Contextualization Approach for Documents utilizing BERT Features
Authors: Nouri Alireza , Hossain Mahmud Shahriar 
Published: March 2023

Abstract

Storytelling is the process of connecting documents one after another representing the evolution of an event. Existing algorithms for storytelling connect events based on content overlaps between consecutive documents ignoring the role of the same term in different documents and the contemporary contexts (e.g., dynamic embeddings) of documents and terms. Due to the lack of role and contemporary contexts in the designs of the existing storytelling methods, the resultant stories frequently jump to documents with the keywords to form a chain but not a meaningful one. In this paper, we present a novel storytelling algorithm -- Contextual Role-Based Storytelling (CoRBS) -- that generates a chain of documents explaining the evolution of an event, addressing role and contemporary context issues of existing methods. CoRBS starts with a given document and moves forward temporally, stitching together role and context-driven documents to represent the evolution of the events that appear in the first document. We define the role of a term in a document as a distribution of similarities of the nearest neighbors of the term based on BERT-embeddings of all terms of that document. Contemporary contexts are incorporated as a mechanism to discover a coherent next document while the story progresses. Our experiments demonstrate that CoRBS generates more meaningful stories compared to other baseline storytelling techniques.
Centrality Based Analysis of Amino Acids Network
Authors: BORAH CHANDRA , ALI TAZID 
Published: March 2023

Abstract
A network is a crucial asset in biology for capturing and exploring interaction data in biological systems of many types, such as protein-protein communications, amino acid associations, gene regulation, and cellular metabolism. In this article, we constructed an amino acid distance matrix by considering each base's positional relevance in a codon, chemical types: Purine and Pyrimidine, and H-bonding count. Based on the amino acid distance matrix, we eventually generated a twenty amino acid network having evolutionary significance. We reviewed multiple centrality metrics to assess the relative importance of amino acids in the proposed network: Degree Centrality, Closeness Centrality, Betweenness Centrality, Eigenvector Centrality, Eccentricity Centrality, and Radiality Centrality. We also looked at the correlation coefficients between the different centrality measures to figure out whether the network is assortative or disassortative. Furthermore, we examined the Clustering Coefficient and Degree Distribution as two effective network measures, and the results seem noteworthy.
Artemisia stelleriana-mediated ZnO nanoparticles for textile dye treatment: a green and sustainable approach
Authors: Puthukulangara Jaison Juhi , Kadanthottu Sebastian Joseph 
Published: March 2023

Abstract
Textile effluents being one of the major reasons for water pollution raises major concern for water bodies and the habitation surrounding them. The lack of biologically safer treatment solutions creates a major concern for the disposal of these effluents. The present study focuses on the degradation of textile dyes using leaf extract of Artemisia stelleriana-assisted nanoparticles of zinc oxide (ZnO-NPs). ZnO NPs synthesized were confirmed using spectroscopic, X-ray diffraction and microscopic analysis. The current research utilizes widely used major textile dyes, Reactive Yellow-145 (RY-145), Reactive Red-120 (RR-120), Reactive Blue-220 (RB-220) and Reactive Blue-222A (RB-222A), which are released accidentally or due to the non-availability of cost-efficient, dependable and environment-friendly degradation methods, making this work a much-needed one for preventing the discharge before treatment. The biosynthesized ZnO-NPs were top-notch catalysts for the reduction of these dyes, which is witnessed by a gradual decrease in absorbance maximum values. After 320 min, ZnO-NPs under UV light exposure showed 99, 95, 94 and 45% degradations of RY-145, RR-120, RB-220 and RB-222A dyes, respectively. The phytotoxicity study conducted at two trophic levels revealed that the A. stelleriana-mediated ZnO-NPs have great potential for the degradation of textile dyes, allowing them to be scaled up to large-scale treatments.
Research and Progress of Probucol in Nonalcoholic Fatty Liver Disease
Authors: Chen Ke-qian , Ke Bo-yi , Cheng Lu , Guan Meng-ting , Wang Zong-bao , Wang Shu-zhi 
Published: March 2023

Abstract:
With the development of the social economy over the last 30 years, non-alcoholic fatty
liver disease (NAFLD) is affected by unhealthy living habits and eating styles and has gradually
become an increasingly serious public health problem. It is very important to investigate the pathogenesis
and treatment of NAFLD for the development of human health. Probucol is an antioxidant
with a bis-phenol structure. Although probucol is a clinically used cholesterol-lowering and antiatherosclerosis
drug, its mechanism has not been elucidated in detail. This paper reviews the chemical
structure, pharmacokinetics and pharmacological research of probucol. Meanwhile, this paper
reviews the mechanism of probucol in NAFLD. We also analyzed and summarized the experimental
models and clinical trials of probucol in NAFLD. Although current therapeutic strategies for
NAFLD are not effective, we hope that through further research on probucol, we will be able to find
suitable treatments to solve this problem in the future.
Εmerging Biomarkers in the Diagnosis and Treatment of Testicular
Tumors
Authors: Evmorfopoulos Konstantinos , Vlachostergios Panagiotis J. , Sountoulides Petros , Tzortzis Vassilios 
Published: March 2023

Abstract:
Testicular germ cell tumors (TGCT) are the leading cause of cancer-related death in young
males between the ages of 20-40. Surgical resection and cisplatin-based chemotherapy can achieve a
cure for the majority of patients with TGCTs, with survival rates of up to 97% for patients diagnosed
at an early stage. The use of serum biomarkers, such as AFP β-HCG, and LDH, plays a significant role
in both diagnosis and evaluation of response to treatment, and despite their low sensitivity and specificity
levels, they are an integral part of the current tumor staging system and daily practice. Molecular
biomarkers, including micro-RNAs and gene-expression profiles, are currently being developed in
TGCTs and could potentially hold a prominent place in the future diagnosis, treatment selection, surveillance,
and prognostication of these tumors. This review discusses how current advances in our understanding
of the underlying biology of TGCTs have helped biomarker discovery, with a focus on the
recognition of key molecular alterations that could serve as potential indicators of disease onset, response
to systemic or/and surgical therapies, and overall clinical course.
Enlargement of the Middle Meningeal Artery may be an Initiating Factor of
Chronic Subdural Hematoma: Three Rase reports and a Literature Review
Authors: Xu Haicheng , Huang Xin , Xu Jin , Jiang Jianfeng , Gong Kai , Gao Heng , Wang Xing , Tao Yichi 
Published: March 2023

Background:
MMA (middle meningeal artery) embolization for the treatment of refractory CSDH (chronic subdural hematoma) was first described by Mandai et
al. in 2000. More surgeons hadbegun to pay attention to such surgery to treat CSDH and explored the changes in the middle meningealartery in the
formation of hematomas.

Case Presentation:
We present three cases of chronic subdural hematoma after head trauma and compared the diameter of middle meningeal artery in MRA images
before and after chronic subduralhematoma to discuss our new understanding of CSDH.

Conclusion:
The enlarging of MMA was found through MRA in patients with craniocerebral trauma on one side but not on the other. However, only the
enlarged side had a subdural hematoma, so we speculate that the enlargement of MMA might be one of the initiating factors of CSDH.
Beyond market neutrality? Central banks and the problem of climate change
Authors: Thiemann Matthias , Büttner Tim , Kessler Oliver 
Published: March 2023

AbstractStarting with a landmark speech by Mark Carney on the ‘Tragedy of the Horizon’ in 2015, climate change entered central banking discourse, causing some of its key convictions to come under new scrutiny. This article traces how initially climate change was firmly embedded in a conventional framework of ‘market completion’ that would allow financial markets to price in negative externality. Yet, over the course of the last seven years, central banks have repositioned their role regarding this problem, taking on a much more active stance, which calls into question the notion of ‘market neutrality’. To trace these discursive changes, this article identifies three discursive layers formed around market-based mechanisms, responsible investment and monetary policy. We show that in the unfolding of the debate, the issue of climate change has altered the self-understanding of central bankers and driven them towards a more active stance where they acknowledge that central bankers shape and make, and not only ‘mirror’, market forces.
Straight Egyptian Arabian skull morphology presents unique surgical challenges compared to the Thoroughbred: a computed tomography morphometric anatomical study
Authors: Pompermayer Endrigo , Hoey Seamus , Ryan Jackie , David Florent , Johnson Jessica P. 
Published: March 2023

Abstract

OBJECTIVE
The objective of this study was to compare the skull morphology of the Straight Egyptian Arabian (SEAR) to the Thoroughbred (TB), using computed tomography (CT) in the context of surgical procedures commonly performed on the equine head.

ANIMALS
Measurements relating to surgical considerations of the equine head were taken from 29 clinically normal adult horses (15 SEAR, 14 TB).

PROCEDURES
A clinical prospective study. Standing skull CTs were performed. Fourteen gross and 10 CT measurements were taken.

RESULTS
Several variables showed a significant difference between groups, in all cases greater in TB. Head length (P < .001) and facial crest length (P < .001) were significantly shorter in SEAR than TB. The head length was shorter relative to body height in SEAR (P < .001). The lateral length of a virtual maxillary bone flap was shorter in SEAR (P < .001). SEAR had smaller craniofacial angles than TB (P = .018).

CLINICAL RELEVANCE
SEAR skull morphology differs significantly from TB, making surgical approaches potentially more challenging. Compared with TB, the shorter facial crest in the SEAR group could contribute to poor surgical access to the maxillary sinus in SEAR due to shorter maxillary flap lengths. Significant differences in the craniofacial angles between SEAR and TB suggest similarities between SEAR and brachycephalic dog breeds, warranting further investigation.
Profile of the Young Patient with Schizophrenia Socio-Cultural Characteristics
Authors: Lacurezeanu Emilia , Moroianu Lavinia-Alexandra , Curis Cecilia , Ardeleanu Valeriu , Gurgas Leonard , Moroianu Marius 
Published: March 2023

Abstract
The importance of early diagnosis is closely related to the fact that the possibility of predicting the disease suggested by a somewhat characteristic psycho-behavioral profile of the adolescent with schizophrenia could constitute the basis for suspecting the condition which would at act interventions to prevent or delay the disease. In support of this statement is the fact that from the sample of patients included in this study aged between 18 and 30 years, at the time of admission, 44% were already retired due to the disease. This fact is representative of the dramatic socio-professional consequences of patients diagnosed with schizophrenia, especially considering the fact that in proportion they were with: high school (32%), vocational school (16%) and higher education (10%). From the patients diagnosed with schizophrenia included in the study 31 benefited from family support and 23 from the community they belong to. Studies show that in the absence of social or family support, the isolation of patients with schizophrenia can trigger depression with a higher in-cidence of self-aggressive behavior and suicidal tendencies.
Life Cycle Assessment of a Hybrid Self-Power Diesel Engine
Authors: Hashemi Fatemeh , Pourdarbani Razieh , Ardabili Sina , Hernandez-Hernandez José Luis 
Published: March 2023

Abstract
In the present study, an attempt was made to simulate the hybrid self-power generation process from a diesel engine and propose sustainable power-share management for this self-power hybrid electrical-diesel platform from the viewpoints of environmental and economic aspects (life cycle perspective). This concept means that when the engine works at part-load condition, we need to bring the engine operating conditions to optimal load, and along with doing the necessary work, in parallel, the rest of the power be used to generate electricity to be stored in the battery for more consumption in addition to reducing pollution and reducing fuel consumption by moving towards sustainable energy production. This case study examines the differences between using a diesel engine at idle and maximum load conditions when less engine power is required and if using a diesel engine in a diesel-electricity hybrid cycle. According to the obtained results, it can be concluded that to achieve the most negligible environmental impact, a lower share of generating power can be allocated to electricity generation in higher cycles than the share of generating electrical power in lower cycles. In other words, by increasing the engine speed, the amount of power consumption used to generate electricity relative to the power required from the diesel engine should be reduced so that the system suffers the most negligible environmental impact.