bluuebunny/crossref_metadata_2025_split huggingface dataset:
The crucial role of CTCF in mitotic progression during early development of sea urchin
Authors: Watanabe Kaichi , Fujita Megumi , Okamoto Kazuko , Yoshioka Hajime , Moriwaki Miki , Tagashira Hideki , Awazu Akinori , Yamamoto Takashi , Sakamoto Naoaki 
Published: July 2023

AbstractCCCTC‐binding factor (CTCF), an insulator protein with 11 zinc fingers, is enriched at the boundaries of topologically associated domains (TADs) in eukaryotic genomes. In this study, we isolated and analyzed the cDNAs encoding HpCTCF, the CTCF homolog in the sea urchin Hemicentrotus pulcherrimus, to investigate its expression patterns and functions during the early development of sea urchin. HpCTCF contains nine zinc fingers corresponding to fingers 2–10 of the vertebrate CTCF. Expression pattern analysis revealed that HpCTCF mRNA was detected at all developmental stages and in the entire embryo. Upon expressing the HpCTCF‐GFP fusion protein in early embryos, we observed its uniform distribution within interphase nuclei. However, during mitosis, it disappeared from the chromosomes and subsequently reassembled on the chromosome during telophase. Moreover, the morpholino‐mediated knockdown of HpCTCF resulted in mitotic arrest during the morula to blastula stage. Most of the arrested chromosomes were not phospholylated at serine 10 of histone H3, indicating that mitosis was arrested at the telophase by HpCTCF depletion. Furthermore, impaired sister chromatid segregation was observed using time‐lapse imaging of HpCTCF‐knockdown embryos. Thus, HpCTCF is essential for mitotic progression during the early development of sea urchins, especially during the telophase‐to‐interphase transition. However, the normal development of pluteus larvae in CRISPR‐mediated HpCTCF‐knockout embryos suggests that disruption of zygotic HpCTCF expression has little effect on embryonic and larval development.
From cryogenic to on‐scalp magnetoencephalography for the evaluation of paediatric epilepsy
Authors: Feys Odile , De Tiège Xavier 
Published: July 2023

AbstractMagnetoencephalography (MEG) is a neurophysiological technique based on the detection of brain magnetic fields. Whole‐head MEG systems typically house a few hundred sensors requiring cryogenic cooling in a rigid one‐size‐fits‐all (commonly adult‐sized) helmet to keep a thermal insulation space. This leads to an increased brain‐to‐sensor distance in children, because of their smaller head circumference, and decreased signal‐to‐noise ratio. MEG allows detection and localization of interictal and ictal epileptiform discharges, and pathological high frequency oscillations, as a part of the presurgical assessment of children with refractory focal epilepsy, where electroencephalography is not contributive. MEG can also map the eloquent cortex before surgical resection. MEG also provides insights into the physiopathology of both generalized and focal epilepsy. On‐scalp recordings based on cryogenic‐free sensors have demonstrated their use in the field of childhood focal epilepsy and should become a reference technique for diagnosing epilepsy in the paediatric population.What this paper adds

Magnetoencephalography (MEG) contributes to the diagnosis and understanding of paediatric epilepsy.
On‐scalp MEG recordings demonstrate some advantages over cryogenic MEG.
The impact of common law on the volume of legal services: An international study
Authors: Dia Enzo , Melitz Jacques 
Published: July 2023

AbstractWe show that the heavy use of legal services relative to output in the US is not a peculiarity of the country but applies to common law countries in general. It can likely be attributed largely to better ability to contract and adapt to changes in the environment. Yet common law also opens significantly more room for rent seeking by lawyers than civil law. Thereby the costs could outweigh the benefits. In supporting this last thesis, we control for other factors besides common law favouring legal services, including real output per capita, openness, and ease of entry into the legal profession.
American financial hegemony, global capital cycles, and the macroeconomic growth environment
Authors: Ba Heather , Winecoff William K. 
Published: July 2023

AbstractGlobal financial cycles have become a growing concern for scholars and policymakers. Recent research has identified these cycles as originating in American markets, at least in part due to policy innovations in the United States. We articulate a previously unidentified, but powerful, mechanism that influence growth (and growth volatility) in the global economy: expansions in the American financial cycle disproportionately affect global credit conditions, leading to a higher incidence of gross capital inflow surges that subsequently create a boom‐bust growth dynamic in recipient economies. We evaluate this argument with an extensive empirical examination of 102 countries from 1975 to 2011 and find substantial support for the argument: US financial market developments produce capital flow cycles that challenge the ability of policymakers to stabilize their macroeconomies. We disaggregate capital flows and find that interbank lending plays a crucial role in driving these outcomes, with the results exhibiting a high degree of robustness to alternative specifications. Domestic policy tools alone may be insufficiently powerful to counteract volatility induced by these capital waves emanating from the core of the global financial system.
Moderate nitrogen retention in temperate heath ecosystem after elevated CO2, drought and warming through 7 years
Authors: Andresen Louise C. , Ambus Per , Beier Claus , Michelsen Anders 
Published: July 2023

AbstractNitrogen (N) dynamic is one of the main controlling factors of responses to climate change in N‐limited terrestrial ecosystems, which rely on nutrient recycling and retention. In this study we investigate the N partitioning in ecosystem compartments of a grassland heath, and the impact of multiple climate change factors on long‐term N retention after 15N pulse labelling. The impacts of elevated carbon dioxide (eCO2), warming and drought and the treatments in combination on ecosystem N retention were investigated in a field scale manipulation experiment. A 6‐year time‐course was assessed by pulse‐labelling with the stable N isotope 15N and by sampling after 1 day, 1 year and 6 years. After 6 years we observed that the total ecosystem retained 42% of the amended 15N across treatments (recovery of the amended 15N in the pool). The fate of the applied 15N was mainly stabilization in soil, with 36% 15N recovery in soil, while the plant compartment and microbial biomass each retained only 1%–2% of the added 15N. This suggests a moderate retention of N, for all treatments, as compared to similar long‐term studies of forest ecosystems. A decreased ammonium and vegetation N pool combined with higher 15N retention in the soil under eCO2 treatments suggests that eCO2 promoted processes that immobilize N in soil, while warming counteracted this when combined with eCO2. Drought treatments contrastingly increased the vegetation N pool. We conclude that as the organic soil layer has the main capacity for N storage in a temperate heathland‐grassland, it is important for buffering nutrient availability and maintaining a resilient ecosystem. However, the full treatment combination of drought, warming and eCO2 did not differ in 15N recovery from the control, suggesting unchanged long‐term consequences of climate change on retention of pulse added N in this ecosystem.
Feedback loops between 3D vegetation structure and ecological functions of animals
Authors: Russo Nicholas J. , Davies Andrew B. , Blakey Rachel V. , Ordway Elsa M. , Smith Thomas B. 
Published: July 2023

AbstractEcosystems function in a series of feedback loops that can change or maintain vegetation structure. Vegetation structure influences the ecological niche space available to animals, shaping many aspects of behaviour and reproduction. In turn, animals perform ecological functions that shape vegetation structure. However, most studies concerning three‐dimensional vegetation structure and animal ecology consider only a single direction of this relationship. Here, we review these separate lines of research and integrate them into a unified concept that describes a feedback mechanism. We also show how remote sensing and animal tracking technologies are now available at the global scale to describe feedback loops and their consequences for ecosystem functioning. An improved understanding of how animals interact with vegetation structure in feedback loops is needed to conserve ecosystems that face major disruptions in response to climate and land‐use change.
Observed forest trait velocities have not kept pace with hydraulic stress from climate change
Authors: Quetin G. R. , Anderegg L. D. L. , Boving I. , Anderegg W. R. L. , Trugman A. T. 
Published: July 2023

AbstractThe extent to which future climate change will increase forest stress and the amount to which species and forest ecosystems can acclimate or adapt to increased stress is a major unknown. We used high‐resolution maps of hydraulic traits representing the diversity in tree drought tolerance across the United States, a hydraulically enabled tree model, and forest inventory observations of demographic shifts to quantify the ability for within‐species acclimation and between‐species range shifts to mediate climate stress. We found that forests are likely to experience increases in both acute and chronic hydraulic stress with climate change. Based on current species distributions, regional hydraulic trait diversity was sufficient to buffer against increased stress in 88% of forested areas. However, observed trait velocities in 81% of forested areas are not keeping up with the rate required to ameliorate projected future stress without leaf area acclimation.
Sampling strategy matters to accurately estimate response curves' parameters in species distribution models
Authors: Bazzichetto Manuele , Lenoir Jonathan , Da Re Daniele , Tordoni Enrico , Rocchini Duccio , Malavasi Marco , Barták Vojtech , Sperandii Marta Gaia 
Published: July 2023

AbstractAimAssessing how different sampling strategies affect the accuracy and precision of species response curves estimated by parametric species distribution models.Major Taxa StudiedVirtual plant species.LocationAbruzzo (Italy).Time PeriodTimeless (simulated data).MethodsWe simulated the occurrence of two virtual species with different ecology (generalist vs specialist) and distribution extent. We sampled their occurrence following different sampling strategies: random, stratified, systematic, topographic, uniform within the environmental space (hereafter, uniform) and close to roads. For each sampling design and species, we ran 500 simulations at increasing sampling efforts (total: 42,000 replicates). For each replicate, we fitted a binomial generalised linear model, extracted model coefficients for precipitation and temperature, and compared them with true coefficients from the known species' equation. We evaluated the quality of the estimated response curves by computing bias, variance and root mean squared error (RMSE). Additionally, we (i) assessed the impact of missing covariates on the performance of the sampling approaches and (ii) evaluated the effect of incompletely sampling the environmental space on the uniform approach.ResultsFor the generalist species, we found the lowest RMSE when uniformly sampling the environmental space, while sampling occurrence data close to roads provided the worst performance. For the specialist species, all sampling designs showed comparable outcomes. Excluding important predictors similarly affected all sampling strategies. Sampling limited portions of the environmental space reduced the performance of the uniform approach, regardless of the portion surveyed.Main ConclusionsOur results suggest that a proper estimate of the species response curve can be obtained when the choice of the sampling strategy is guided by the species' ecology. Overall, uniformly sampling the environmental space seems more efficient for species with wide environmental tolerances. The advantage of seeking the most appropriate sampling strategy vanishes when modelling species with narrow realised niches.
High piezoelectric and dielectric constant of Fe/In Co‐doped KNN‐based ceramics regulated by lattice distortion
Authors: Leng Wangzhe , Wan Guoxi , Liu Yanyu , Ma Rui , Du Yi 
Published: July 2023

AbstractThe new (0.96‐x)(K0.48Na0.52Nb0.96Sb0.04)O3‐0.04(Bi0.5Ag0.5)ZrO3‐x(Fe2O3‐In2O3) ceramics with high dielectric, and electromechanical coupling properties were designed. In this work, the effect of KNN‐based ceramics lattice distortion (c/a) and microstructure on the electrical properties was explored by varying the doping amount of Fe3+ and In3+. The problem of a large number of oxygen vacancies generated by the volatilization of K and Na can be well solved by introducing Fe3+ and In3+. The bulk density increases significantly and the maximum value is about 4.52 g/cm3.The sample with x = 0.003 has the smallest c/a, and exhibits the best piezoelectric and dielectric properties (d33 = 536 pC/N, εr = 3432 and kp = 55.8 %). Low doping concentration of Fe2O3 is considered a “soft” addition for KNN‐based piezoelectric ceramics. The study of this mechanism provides a new idea to regulate the electrical performance of KNN‐based ceramics.
Effect of illness perception on predicting breast cancer‐related lymphedema risk management behaviours among breast cancer patients: A comparison between dimensions and profiles
Authors: Chen Jing , Wang Ying , Luo Xia , Zhang Yue , Zhang Xiaomin , Li Mingfang , Xiong Chenxia , Guo Zijun , Zhao Meng , Yan Jun 
Published: July 2023

AbstractAimThis study aimed to explore the utility of latent profile analysis of illness perception, in comparison to treating illness perception as several dimensions, to predict breast cancer‐related lymphedema risk management behaviours among Chinese breast cancer patients.MethodsThis is a 3‐month longitudinal study. From August 2019 to January 2021, patients who recently underwent breast cancer surgery including axillary lymphadenectomy were recruited. Illness perception and risk management behaviours were measured by breast cancer‐related lymphedema specific questionnaires before discharge following surgery (n = 268) and at 3 months postsurgery (n = 213), respectively.ResultsTreating illness perception as several dimensions, ‘illness coherence’ and ‘timeline (cyclical)’ dimensions were found to be significantly associated with breast cancer‐related lymphedema risk management behaviours. Using the latent profile analysis, two illness perception profiles were identified and significant differences were revealed in breast cancer‐related lymphedema risk management behaviours between them. Overall, illness perception profiles explained smaller amounts of variability in breast cancer‐related lymphedema risk management behaviours than illness perception dimensions.ConclusionFuture studies could combine these two different perspectives of illness perception regarding breast cancer‐related lymphedema into the design of interventions to improve breast cancer‐related lymphedema risk management behaviours.
Characterization of biodegradable core–clad borosilicate glass fibers with round and rectangular cross‐section
Authors: Hongisto Mikko , Ghanavati Sonya , Lemiere Arnaud , Hauss Gregory , Boraiah Shashank , Cornet Louis , Poulon‐Quintin Angeline , Pagnoux Dominique , Bernard Dominique , Massera Jonathan , Petit Laeticia , Jubera Veronique , Danto Sylvain 
Published: July 2023

AbstractHere, we report on core–clad bioactive borosilicate fibers, that we have prepared both with round and rectangular cross‐section profile. The exposed approach, which relies on the stacking and drawing of glass slabs, demonstrates our ability to develop bioactive‐based glass fibers with tailored cross‐section profiles. Tens‐of‐meters‐long fibers were successfully drawn, although suffering from elevated losses in the case of the rectangular ones. The response of the fibers in simulated body fluid was studied for both geometries. We found that a round cladding can act as protective layer, tempering effects of the corrosion. We also noticed that rectangular fibers are more prone to degradation, the enhanced corrosion beginning from their sharp corners as they accumulated residual tensile stress during drawing. To the best of our knowledge, this is the first report on the effect of residual tensile stresses from surface tension deformations applied to the corrosion of rectangular fibers. As geometry plays a critical role on the biodegradation behavior of the fiberglass, we believe the enclosed results could lead to the design of fiber devices with tailored cross‐section profile in order to tune their rate of degradation on solely based geometrical effects.
Seeing COVID‐19 is believing: Direct and indirect experiences with COVID‐19 predict health behaviors through conspiracy beliefs and risk perception
Authors: Evans Nicholas D. , Fetterman Adam K. 
Published: July 2023

AbstractWhen people are confronted with research that contradicts their own personal experiences, they tend to deny the science. Using a secondary multinational data set collected during the early stages of the coronavirus disease 2019 (COVID‐19) pandemic (N = 46,490), we tested this “seeing is believing” effect as it relates to the link between direct and indirect personal experience with COVID‐19 and public health behaviors (PHBs) through COVID‐19 conspiracy beliefs and perceived risk of infection. Indirect experience with COVID‐19 was associated with lower endorsement of COVID‐19 conspiracy beliefs, which negatively predicted risk perception of infection, and, in turn, positively predicted PHBs. However, direct experience positively predicted COVID‐19 conspiracy beliefs, while it negatively predicted perceived risk. Moreover, while indirect experience positively predicted PHBs, direct experience largely negatively predicted PHBs. Implications of these findings as it relates to the “seeing is believing” effect are discussed.
Effect of CAD‐CAM restorative materials and scanning aid conditions on the accuracy and time efficiency of intraoral scans
Authors: Cho Jun‐Ho , Çakmak Gülce , Yilmaz Burak , Yoon Hyung‐In 
Published: July 2023

AbstractPurposeThis in vitro study aimed to evaluate the effects of restorative materials and scanning aid conditions on the accuracy and time efficiency of intraoral scans.Materials and MethodsIdentical anatomic contour crowns were fabricated using the following materials: hybrid ceramic, 3 mol% yttria‐stabilized tetragonal zirconia, 4 mol% yttria‐partially stabilized zirconia, 5 mol% yttria‐partially stabilized zirconia, cobalt–chromium (Co–Cr), resin, lithium disilicate, and feldspathic ceramic. The models were digitized and analyzed for accuracy (n = 10) under three scanning aid conditions (powder‐based, liquid‐based, and none). Additionally, the effect of metal restorations on the scan accuracy of other crowns was investigated. The scan time for complete arches was also recorded. One‐way analysis of variance, Welch analysis of variance, and post‐hoc comparison or independent t‐tests were used for trueness analysis, and the F‐test was used to examine precision (α = 0.05).ResultsSignificant differences were observed in the trueness of the different restorative materials under the no‐scanning aid condition (P < 0.05). In contrast, no statistically significant difference among the groups was observed with the powder‐ or liquid‐based scanning aid. For each restorative material, the no‐scanning aid condition showed significantly lower trueness than that with powder‐ or liquid‐based scanning aids. The presence of a Co–Cr crown did not affect the trueness of other restorations in the arch. The scan time efficiency significantly increased on applying a powder‐ or liquid‐based scanning aid.ConclusionsUsing a scanning aid was effective to improve the scan accuracy of the tested restorative materials and scan time efficiency. Applying scanning aids to existing intraoral restorations can help improve prosthesis quality and reduce the need for clinical adjustment at the occlusal or proximal contacts.
Influence of polishing technique and coffee thermal cycling on the surface roughness and color stability of additively and subtractively manufactured resins used for definitive restorations
Authors: Çakmak Gülce , Oosterveen‐Rüegsegger Alice Lisa , Akay Canan , Schimmel Martin , Yilmaz Burak , Donmez Mustafa Borga 
Published: July 2023

AbstractPurposeTo evaluate how different polishing techniques and coffee thermal cycling affect the surface roughness and stainability of additively and subtractively manufactured resins used for definitive prostheses.Materials and MethodsTwo additively manufactured composite resins (Crowntec, CT and VarseoSmile Crown Plus, VS) and a subtractively manufactured resin nanoceramic (Cerasmart, CS) were used to fabricate 90 rectangular‐shaped specimens (14 × 12 × 1 mm) (n = 30). After baseline surface roughness (Ra) measurements, specimens were divided into three groups based on the polishing technique; conventional polishing with a 2‐stage polishing kit (CP) and surface sealant application (Optiglaze, OG or Vita Akzent LC, VA) (n = 10). After polishing, specimens were subjected to 10,000 cycles of coffee thermal cycling. Ra and color coordinate measurements were performed after polishing and after coffee thermal cycling. Color difference (ΔE00) was calculated. Scanning electron microscope images were taken at each time interval. Kruskal–Wallis or 1‐way analysis of variance (ANOVA) were used to evaluate Ra of materials within each polishing‐time interval pair and different polishing techniques within each material‐time interval pair, while Friedman or repeated measures ANOVA were used to evaluate Ra at different time intervals within each material‐polishing pair. ΔE00 was assessed with 2‐way ANOVA (α = 0.05).ResultsOther than VA‐after polishing (p = 0.055), tested materials had significantly different Ra within each polishing‐time interval pair (p ≤ 0.038). When Ra differences among different polishing techniques within each material‐time interval pair were considered, CS had differences after coffee thermal cycling, CT had differences before polishing and after coffee thermal cycling, and VS had differences within each time interval (p ≤ 0.038). When Ra differences among different time intervals within each material‐polishing pair were considered, significant differences were observed among all pairs (p ≤ 0.016), except for CS‐VA (p = 0.695) and VS‐VA (p = 0.300). ΔE00 values were affected by material and polishing technique interaction (p = 0.007).ConclusionsRa of CS was similar to or lower than the Ra of other materials, regardless of the time interval or polishing technique. CP mostly led to lower Ra than other polishing techniques, whereas VA resulted in a high Ra regardless of the material‐time interval pair. Polishing reduced the Ra, while coffee thermal cycling was found to have a small effect. Among tested material‐polishing pairs, only CS‐VA had moderately unacceptable color change when previously reported threshold values were considered.