bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Comparative Study of Ultrasonography (USG) and Computed Tomography for Detecting Ureteric Calculi in Patients with Acute Flank Pain, and Analysis of Factors Influencing Ultrasound Detection Rates: Findings from a Tertiary Hospital in Nepal
Authors: Khatiwada Bishnu , Mahat Asim , Yadav Gopal Kumar , Duwadi Bikash , Mishra Upama , Bhusal Amrit , Yadav Priti , Khadka Hensan 
Published: September 2023

Abstract
Introduction:
To address the unmet clinical need, we aimed to analyze the roles of ultrasound (US) and computed tomography (CT) scans in evaluating ureteric calculi in patients with acute flank pain. Additionally, we assessed the factors affecting the US detection rates in the same group of patients.
Methods
We conducted a cross-sectional study using purposive sampling, involving 87 participants who presented with acute flank pain at a tertiary hospital in Nepal. Ethical clearance was obtained from the institutional review board.
Results
Among the 87 patients presenting with acute flank pain, the majority were male (51, 58.62%). Of the 78 cases with CT-detected ureteric calculi, the most common locations were distal ureter (23/78, 29.49%), followed by proximal ureter (21/78, 26.92%), and pelvic-ureteric junction (PUJ) (20/78, 25.64%). Ultrasound demonstrated varying sensitivities for detecting ureteric calculi: 95.00% for PUJ, 100.00% for vesicoureteric junction (VUJ), 66.67% for proximal ureter, and 56.52% for distal ureter calculi. The highest sensitivity was observed for calculi greater than 15 mm (100%), followed by 10.1 to 15 mm (77.7%). Overall, ultrasound exhibited a sensitivity of 76.92%, a specificity of 100%, and an accuracy rate of 79.31% in detecting calculi. Notably, patients with hematuria had significantly higher odds of ultrasound-detected ureteric calculi (OR: 36.68, 4.54-296.26, P < 0.01) than those without hematuria. However, age, hydronephrosis, calculi location, and laterality were not found to be significantly associated with ultrasound detection.
Conclusions
Due to its good sensitivity, ultrasound can serve as the first-line investigation for individuals experiencing acute flank pain, given its cost-effectiveness and radiation-free nature when compared to CT scans. CT scans should be reserved for patients exhibiting clinical symptoms of severe colic who have previously undergone a negative ultrasound (USG).
Adverse Childhood Experiences and Maladaptive Daydreaming
Authors: Moment Lauren 
Published: September 2023

Abstract
This paper explores the concept of maladaptive daydreaming, a phenomenon characterized by excessive and immersive daydreaming that interferes with daily functioning. While normative daydreaming can be an adaptive behavior that may contribute to planning, future goals, and creativity, maladaptive daydreaming can lead to poor academic, interpersonal, and professional performance and increased social isolation. The study found a moderate positive correlation between maladaptive daydreaming and adverse childhood experiences, suggesting that childhood trauma may contribute to the development of maladaptive daydreaming. Maladaptive daydreaming was also significantly positively correlated with depression and anxiety, indicating potential comorbidity with these mental health concerns. The study highlights the need for increased awareness and understanding of maladaptive daydreaming as a potential mental health concern, particularly for individuals who have experienced adverse childhood experiences. Interventions aimed at improving coping skills and addressing underlying trauma may be beneficial in reducing the negative impact of maladaptive daydreaming on daily functioning.
Investigating Medical Students' Attitudes Towards Patient’s Bills of Rights: Implications for Ethical Care
Authors: Abdollahi Amirsaleh , Varaki Alireza Karimi , Frouzanian Mehran , Yousefi Mohammad , Shamshiriyan Mostafa , Rezaee Ali , Darabinia Morteza , Alipour Abbas 
Published: September 2023

Abstract
Introduction
The provision of ethical care is a critical component of the medical profession, and adherence to the patient's bill of rights is essential to ethical care. This study aimed to investigate medical students’ attitudes toward the provisions of the patient's ethical charter.
Methods
A cross-sectional descriptive-analytical study was conducted between March 2022 to July 2022 among several medical students in the 1st to 10th semesters at Mazandaran University of Medical Sciences. Data were collected using valid and reliable questionnaires containing 22 questions about the patient's bill of rights provisions. The questionnaire scoring scale was based on the five-point Likert scale. Students' views were classified into three levels: favorable, relatively favorable, and unfavorable.
Results
230 medical students participated in the study, with a mean age of 21.96 ± 2.89, and 37% were women. The average student had a relatively favorable attitude toward the patient's Bill of Rights provisions. There were no significant differences between men and women or between students who had related programs about the patient's bill of rights and those who did not. The correlation between age and semester by attitude score towards the patient's right charter showed a significant relationship. With increasing age, the attitude toward patient rights standards worsened. Higher-semester students were more unfavorable toward the patients' bill of rights provision.
Conclusion
The study findings suggest that implementing medical courses and programs related to the patient's bill of rights could be more effective. Medical students' attitudes towards the patient's ethical charter worsen with increasing age and academic term. Further studies are required to identify the reasons behind this trend and improve the implementation of medical courses and programs related to the patient's bill of rights.
Ebola Virus Disease: Knowledge, Attitude and Perception - The Case of Uganda
Authors: KIBUUKA RONALD , Kagoya Enid Kawala , Nsubuga Allan. G. , Ahaisibwe Bonaventure , Atuhairwe Irene , Nakatudde Prossy , Kizito Prisca , Jesca Atugonza , Okibure Ambrose , Okello Francis , Nyangoma Faith , Nakawuka Bety , Nakabaale Mark , Nakawuki Ashley , Namara Racheal , Catherine Asiimwe W. , Tamale Elvis , Akol Patrick , Nabwire Lilian , Waako Paul , Wandabwa Julius , Musaba Milton , Barugahare Banson 
Published: September 2023

Abstract
Introduction
Ebola virus disease (EVD) is a severe hemorrhagic disease caused by the Ebola Virus. The EVD is highly infectious with a high fatality rate. Uganda has experienced multiple Ebola outbreaks. To address the need for renewed engagement between the government and community, this study aimed to assess knowledge, attitudes, and preventive practices towards EVD in different regions of Uganda.
Objectives
To determine the level of knowledge, attitude and prevention practices towards the Ebola Virus in the different regions of Uganda.
Methods
A descriptive community-based cross-sectional design was conducted. The study implored a quantitative approach. Participants were randomly assessed of their knowledge, attitude and prevention of the EVD. Data was analyzed with Stata 15.
Results
The study enrolled 737 community members. The majority of the community members demonstrated good knowledge levels of EVD. Participants who obtained information from social media had higher knowledge levels across the respective study regions of the country; Mbale (OR = 9.8, CI: 2.2–43.5, p = 0.03) and Mbarara (OR = 8.6, CI: 4.0-18.45, P = 0.001) cities. However, in Lira city, the association between social media and knowledge levels was not statistically significant. The use of television as an information source significantly positively affected knowledge levels in Mbale city, Eastern region (OR = 4.0, CI: 1.6–10.1, P = 0.004). Health workers exhibited significantly higher knowledge compared to the others (OR = 8.9, CI: 1.1–69.6, P = 0.038) Knowing how to approach a suspected case, had a significant level in Mbale city, Eastern region (OR = 8.6, CI: 2.4–30.4, P = 0.001). Similarly, knowing how to use PPE was associated with higher levels in Lira city north Eastern region (OR = 2.0, CI: 1.1–3.3) P = 0.021. The majority both females (94.4%, 91.7% and males (88.9%, 90%) agreed to the isolation of the case and the family respectively avoid the risk of infection and death, which also led to a discriminatory attitude towards survivors and a distrust of EVD treatment. All participants 74.3% and 76.9% female and male perceived the Ebola treatment as very expensive.
Conclusion
Our results are in tandem with previous reports. we found that urban communities are more knowledgeable and have better attitudes towards pandemic outbreaks, though this varies from region to region. Public perceptions, community engagement and social media may be useful tools in mapping knowledge and awareness strategies for disease outbreaks.
The Experiences and Perceptions of Campus Resource Utilization by University Students with Childhood Domestic Violence Exposure Histories
Authors: Allen Amie , Ravi Kristen , Haselschwerdt Megan , Niederhauser Victoria 
Published: September 2023

Abstract
Objective: The purpose of this study was to examine the campus resource utilization experiences of university students with childhood domestic violence exposure (CDV) histories.
Participants: 368 students attending a public, 4-year university in the Southeastern United States.
Methods: Participants completed a web-based survey with variables including CDV, campus resource utilization and perceptions of said resources, and participant resource suggestions.
Results: Most students utilized at least one health-related campus resource, with the student health and counseling centers as the most common and helpful. Suggested areas for institutional and service provider growth include enhanced advertisement and accessibility for existing resources and added support groups.
Conclusions: College campuses provide unique opportunities to support young adults with CDV histories. Tailoring programming to students with CDV histories has the potential to improve student's success in and beyond college.
Clinical spectrum of adult-onset Still’s disease in patients presenting at a tertiary care hospital in Pakistan: A 16-year retrospective descriptive study
Authors: Riaz Mehmood , Baqir Syed Mujtaba , Isra Ahmed , Karim Zohair , Arshad Ainan 
Published: September 2023

Abstract
Introduction: Adult-onset Still's Disease (AOSD) is a rare systemic auto-inflammatory disorder with limited available data and regional variations in presentation. This study aims to shed light on the clinical and laboratory spectrum and associated complications of AOSD patients at a tertiary care center. The goal is to facilitate early diagnosis and management in cases lacking characteristic features.
Methods: We conducted a retrospective review of patient records from January 2005 to February 2021, utilizing the Yamaguchi criteria for AOSD diagnosis. Clinical symptoms, laboratory values, therapeutic approaches and complications were analyzed. Descriptive statistics were employed to illustrate disease patterns.
Results: The study included patients with a mean age of 37.6 years, with a male-to-female ratio of 3:5. Fever and arthralgia were prevalent in 100% of cases, while a salmon-colored rash was observed in 62.5%, and leukocytosis in 75%. Additional symptoms included sore throat and recent lymphadenopathy in 37.5%, hepatomegaly and/or splenomegaly on imaging in 50%, and abnormal liver function tests in 87.5% cases. Steroids were the primary first-line treatment. Notably, most patients did not exhibit the common complications previously reported in AOSD.
Conclusion: The clinical findings in our study closely resemble those reported in other regions, emphasizing the need for a comprehensive analysis of AOSD. This study underscores the importance of considering AOSD as a potential diagnosis, even in atypical presentations, to enhance patient care by minimizing delays in diagnosis and enabling prompt management.
Key points
• This study presents the first national data on AOSD in Pakistan
• AOSD mostly affects younger adults, with a mean age of 37.6 years
• Common AOSD symptoms include fever, arthralgia, leukocytosis, high ferritin levels, and abnormal liver function, but the rash's prevalence varies by region.
Insights into Metabolic Engineering of Bioactive Molecules in Tetrastigma
Hemsleyanum Diels & Gilg: A Traditional Medicinal Herb
Authors: Ajeesh Krishna T.P. , Maharajan T. , Adarsh Krishna T.P. , Antony Ceasar S. 
Published: September 2023

Abstract:
Plants are a vital source of bioactive molecules for various drug development processes.
Tetrastigma hemsleyanum is one of the endangered medicinal plant species well known to the
world due to its wide range of therapeutic effects. Many bioactive molecules have been identified
from this plant, including many classes of secondary metabolites such as flavonoids, phenols, terpenoids,
steroids, alkaloids, etc. Due to its slow growth, it usually takes 3-5 years to meet commercial
medicinal materials for this plant. Also, T. hemsleyanum contains low amounts of specific bioactive
compounds, which are challenging to isolate easily. Currently, scientists are attempting to increase
bioactive molecules' production from medicinal plants in different ways or to synthesize
them chemically. The genomic tools helped to understand medicinal plants' genome organization
and led to manipulating genes responsible for various biosynthesis pathways. Metabolic engineering
has made it possible to enhance the production of secondary metabolites by introducing manipulated
biosynthetic pathways to attain high levels of desirable bioactive molecules. Metabolic
engineering is a promising approach for improving the production of secondary metabolites over a
short time period. In this review, we have highlighted the scope of various biotechnological approaches
for metabolic engineering to enhance the production of secondary metabolites for pharmaceutical
applications in T. hemsleyanum. Also, we summarized the progress made in metabolic engineering
for bioactive molecule enhancement in T. hemsleyanum. It may lead to reducing the destruction
of the natural habitat of T. hemsleyanum and conserving them through the cost-effective
production of bioactive molecules in the future.
Coping Strategies employed by Muslim Academia during Covid-19: A narrative review
Authors: Aboo Bakar Rofiza , Tazijan Farina Nozakiah , Sudarsono Sudarsono , Ikhsanudin Ikhsanudin 
Published: September 2023

The global educational scenario has undergone a major transformation due to the COVID-19 pandemic, leading to substantial conflict and disturbances in the process of imparting and acquiring knowledge. The scarcity of studies on Muslim academia’s coping mechanisms amidst the COVID-19 outbreak highlights the necessity to investigate their distinct encounters. Drawing on existing literature, this narrative review explores the Islamic-based coping strategies they employed. Educators, mental health practitioners, and other stakeholders may acknowledge the significance of these coping strategies and integrate them into mental health and educational programmes to aid the Muslim academia and alike amidst the pandemic and beyond.
Iterative Patient Testing of a Stimuli-Responsive Swallowing Activity Sensor to Promote Extended User Engagement During the First Year After Radiation: Multiphase Remote and In-Person Observational Cohort Study
Authors: Shinn Eileen H , Garden Adam S , Peterson Susan K , Leupi Dylan J , Chen Minxing , Blau Rachel , Becerra Laura , Rafeedi Tarek , Ramirez Julian , Rodriquez Daniel , VanFossen Finley , Zehner Sydney , Mercier Patrick P , Wang Joseph , Hutcheson Kate , Hanna Ehab , Lipomi Darren J 
Published: September 2023

Background
Frequent sensor-assisted monitoring of changes in swallowing function may help improve detection of radiation-associated dysphagia before it becomes permanent. While our group has prototyped an epidermal strain/surface electromyography sensor that can detect minute changes in swallowing muscle movement, it is unknown whether patients with head and neck cancer would be willing to wear such a device at home after radiation for several months.

Objective
We iteratively assessed patients’ design preferences and perceived barriers to long-term use of the prototype sensor.

Methods
In study 1 (questionnaire only), survivors of pharyngeal cancer who were 3-5 years post treatment and part of a larger prospective study were asked their design preferences for a hypothetical throat sensor and rated their willingness to use the sensor at home during the first year after radiation. In studies 2 and 3 (iterative user testing), patients with and survivors of head and neck cancer attending visits at MD Anderson’s Head and Neck Cancer Center were recruited for two rounds of on-throat testing with prototype sensors while completing a series of swallowing tasks. Afterward, participants were asked about their willingness to use the sensor during the first year post radiation. In study 2, patients also rated the sensor’s ease of use and comfort, whereas in study 3, preferences were elicited regarding haptic feedback.

Results
The majority of respondents in study 1 (116/138, 84%) were willing to wear the sensor 9 months after radiation, and participant willingness rates were similar in studies 2 (10/14, 71.4%) and 3 (12/14, 85.7%). The most prevalent reasons for participants’ unwillingness to wear the sensor were 9 months being excessive, unwanted increase in responsibility, and feeling self-conscious. Across all three studies, the sensor’s ability to detect developing dysphagia increased willingness the most compared to its appearance and ability to increase adherence to preventive speech pathology exercises. Direct haptic signaling was also rated highly, especially to indicate correct sensor placement and swallowing exercise performance.

Conclusions
Patients and survivors were receptive to the idea of wearing a personalized risk sensor for an extended period during the first year after radiation, although this may have been limited to well-educated non-Hispanic participants. A significant minority of patients expressed concern with various aspects of the sensor’s burden and its appearance.

Trial Registration
ClinicalTrials.gov NCT03010150; https://clinicaltrials.gov/study/NCT03010150
Multidrug-Resistant Strain ExPEC Isolat Asal Puyuh (Coturnix coturnix japonica)
Authors: Prihtiyantoro Wahyu , Purnomo Agus , . Sudarisman , . Khusnan 
Published: September 2023

AbstractExtraintestinal Escherichia coli (ExPEC) causes colibacillosis in poultry, including quail. ExPEC is a pathogenic E. coli that causes colibacillosis outside the gastrointestinal tract of poultry, in the form of peritonitis, pericarditis, salpingitis, synovitis, osteomyelitis, septicemia, pneumonitis, nephritis, pleurisy, proventriculitis and ventriculitis. In poultry farming antibiotics are used to promote growth and egg production, prevention and treatment of bacterial infections. Antibiotic resistance is a new problem that arises in poultry farming. In this study, 24 isolates of ExPEC strain from quail were used. These isolates did not differentiate sorbitol in the MacConkey (SMAC) sorbitol test assay. Antibiotic resistance was tested based on the inhibition of bacterial growth on Muller Hinnton Agar (MHA) media. 10 types of antibiotics were used to observe their resistance in all isolates. Resistance to Amikacin (87.5%), Ampicillin (87.5%), Ciprofloxacin (100%), Clindamycin (95.83%), Cefoxacin (25.0%), Doxycycline (87.5%), Erythromycin (100%), Gentamicin (95.83%), Penicillin (95.83%) and Tetracycline (83.3%). The isolates had multidrug-resistance between 3 to 10 types of antibiotics. This study showed that ExPEC isolates from quail were resistant to the type of antibiotics tested, so that the use of antibiotics in quail culture should be limited to reduce and prevent the emergence of new antibiotic resistance. Keyword: Escherichia coli, sorbitol-negative, quail, antibiotics resistance
Otoritas Dakwah Virtual dalam Tafsir Rahmat H. Oemar Bakry: Analisis Intertekstualitas Julia Kristeva
Authors: Hidayat M. Riyan , El-Feyza Muhafizah , HS Muh. Alwi , Akmaluddin Muhammad , Nazarmanto Nazarmanto 
Published: September 2023

Kegiatan dakwah di Indonesia mengalami gejolak yang begitu besar, dimana sosial media digunakan sebagai wadahnya. Kemudian, dakwah yang dilakukan dari satu individu merupakan kewajiban muslim Indonesia dan dunia. Penyebaran konten dakwah dalam dunia virtual seakan meresahkan para viewers muslim tentang keaslian dan keotentikan sumber konten yang disebarkan oleh sebuah akun di media sosial dari berbagai flatform. Namun, melalui Tafsir Rahmat penulis melihat bahwa ada tawaran kebaharuan tentang otoritas dakwah virtual agar tidak terjadinya ekspansi ilmu yang cacat. Terlebih lagi, pemahaman yang beragam dari para content creator berpotensi mengadu domba dan menyebarkan propaganda di khalayak luas. Melalui kajian yang berbasis kepustakaan (library research) dengan menggunakan kacamata intertekstualitas yang dipelopori oleh Julia Kristeva akan tergambar pesan dan substansi tawaran H. Oemar Bakry dalam melihat problematika tersebut. Dengan demikian, tulisan ini bertujuan merespon tawaran baru dengan membuat sebuah lembaga di bawah nauangan pemerintah tentang otoritas dakwah virtual. Tujuannya untuk menanggulangi pesan-pesan dakwah yang sifatnya provokatif, tendensius, bias, memihak, subjektif, evokatif yang berseliweran di jagad maya. Hasil dari penelitian ini akan tergambar bahwa kajian ini telah menghasilkan temuan baru bahwa H. Oemar Bakry menawarkan makna akan dibentuk kelompok juru dakwah yang kuat, jujur, dan teratur. Fungsi dari juru dakwah yakni menjadi sumber referensi khazanah keilmuan Islam Indonesia.
Masyarakat Tionghoa di Solo dan organisasi sosial: Dari terbentuknya CMKH sampai PMS
Authors: Halim Chandra , Aji Sampurno Silverio R.L. 
Published: September 2023

Tulisan ini membahas kebudayaan orang-orang Tionghoa di Solo, yang di dalamnya mengangkat permasalahan kehidupan organisasi mereka. Kedatangan orang-orang Tionghoa di Solo belum dapat dipastikan waktu awalnya, namun dapat disebutkan bahwa keberadaan mereka sudah ada sejak berdirinya kerajaan Islam. Dengan menggunakan metode historis, penelitian ini sampai pada tahap kesimpulan bahwa sejak keberadaan orang-orang Tionghoa di Solo sekitar tahun 1740-an, mereka telah memiliki peranan penting melalui organisasi-organisasi yang dibentuk.