bluuebunny/crossref_metadata_2025_split huggingface dataset:
Biopestcidal Potentials of Erythrophleum Africanum (Benth.) Harms Stembark and Leaf Extracts for the Management and Control of Termites
Authors: Joshua John Israila , Gushit John Stephen , Ior Lydia Doosuur , Ali Ahmed Difa , Dogo Goni Abraham 
Published: July 2023

Abstract
Background
Environmental concerns over the use of large quantities of synthetic insecticides for termite control owing to the huge pollution burdens and modern environmental health hazards (MEHH) of such chemicals on non-target living beings and other environmental element. To reduce the burden of such chemicals on the environment, the use of plant-based extracts to control termites could be an effective alternative if properly explored. One such plant with potential for anti-termite activity was assessed in this study.
Result
The phytochemical evaluation indicated high presence of alkaloids, cardiac glycosides, flavonoids and steroids in the stem-bark, while anthraquinones, saponins, tannins and terpenes were observed in the leaf extract. The GC-MS analysis revealed the presence of twenty-five compounds and thirty-four compounds in the leaf and stem bark extract respectively. On the other hand, the termiticidal activity of the leaf and stembark extracts was more against Reticulitermes flavipes Kollar (Subterranean) termites than Reticulitermes tibialis (Arid Land Subterranean) termites. Further study revealed that a concentration of 30.35 mg/L and 183.31 mg/L of the leaf extract was required to knock-off 50% and 90% of the Reticulitermes tibialis termites respectively, while a concentration of 40.76 mg/L was required to knock-off 50% and 66.19 mg/L is needed to knock-off 90% of the Reticulitermes flavipes Kollar termites Similarly, for 50% of the Reticulitermes tibialis termites to be knocked-off, 48.20 mg/L of the stembark extract was required. To achieve higher mortality of the termites (90%) of the Reticulitermes tibialis termites, 243.26 mg/L of the stembark was required. Concentrations of 33.24 mg/L and 54.35 mg/L of the stembark were required to knock-off 50% and 90% of the Reticulitermes flavipes Kollar termites respectively. E. africanum ethanol leaf and stembark extracts can be classified as Category 4 which gives the indication of moderate acute toxicity hazard.
Conclusion
E. africanum extract will therefore, serve as a safe, efficacious and environmentally friendly pesticide for use against termites.
Biomechanical study of pedicle screw construct and locking compression plate fixation for the treatment of posterior pelvic ring injuries: A finite element analysis
Authors: Zhang Jun , Wei Yan , Li Guoding , Wang Jian , Yu Baoqing 
Published: July 2023

Abstract
Objective
The pedicle screw construct and locking compression plate have been clinically investigated for the treatment of posterior pelvic ring injuries. However, few studies are available that evaluate the biomechanical performance of these two pelvic fixation techniques. The aim of this study was to compare the construct stability, model displacement and stress distribution of two implants with a finite element (FE) method.
Methods
A three-dimensional FE model of spine-pelvis-femur complex with ligaments was reconstructed from computed tomography images. The unstable posterior pelvic ring injury was created, which was fixed with the pedicle screw construct or locking compression plate. A follower load of 400 N was applied to the upper surface of the vertebrae to simulate upper body weight, while the ends of the proximal femurs were fixed.
Results
The construct stiffness of the pedicle screw model was 2 times that of the plate fixation. The maximum displacement of the pedicle screw model decreased by 51.2% compared with the plate fixation. The peek stresses of the implant and pelvis in the pedicle screw model decreased by 80.4% and 25% when compared with the plate model (44.57 MPa and 34.48 MPa in the pedicle screw model, and 227.47 MPa and 45.97 MPa in the plate model).
Conclusions
The study suggested that the pedicle screw construct could provide better fixation stability compared with locking compression plate, and serves as the recommended fixation method for the treatment of posterior pelvic ring injuries.
Exploring the Association between Rosacea and Acne by Integrated Bioinformatics Analysis
Authors: Liang Jingchen , Chen Ying , Wang Zihao , Wang Yawen , Mu Shengzhi , Zhang Dewu , Zeng Weihui , Wang Zhao 
Published: July 2023

Abstract
Clinically, rosacea occurs frequently in acne patients, which hints the existence of shared signals. However, the connection between the pathophysiology of rosacea and acne are not yet fully understood. This study aims to unveil molecular mechanism in the pathogenesis of rosacea and acne. We identified differentially expressed genes (DEGs) by limma and weighted gene co-expression network analysis and screened hub genes by constructing a protein-protein interaction network. The hub genes were validated in different datasets. Then, we performed a correlation analysis between the hub genes and the pathways. Finally, we predicted and validated transcription factors of hub genes, performed the immune cell infiltration analysis using CIBERSORT, and calculated the correlation between hub genes and immune cells. A total of 169 common DEGs were identified. which were mainly enriched in immune-related pathways. Finally, hub genes were identified as IL1B, PTPRC, CXCL8, MMP9, CCL4, CXCL10, CD163, CCR5, CXCR4, and TLR8. 9 transcription factors that regulated the expression of hub genes were identified. The infiltration of γδT cells was significantly increased in rosacea and acne lesions and positively linked with almost all hub genes. These identified hub genes and immune cells may play a crucial role in the development of rosacea and acne.
Blood glucose estimation using third person continuous glucose monitoring data via complete ensemble empirical mode decomposition with adaptive noise and long-short-term memory networks
Authors: Wing-Kuen Bingo , Liang Junjian , Zhao Weiren , Li Rui , Liu Jiaqi 
Published: July 2023

Abstract
Background Blood glucose estimation is critical for monitoring the health of patients with diabetes. Traditionally, it has been performed invasively, via pricking a fingertip to draw a small amount of blood for analysis. However, this type of approach causes pain to patients in the long-term. More recently, micro-invasive approaches have been proposed as alternatives; however, these new methods can be quite costly.
Methods To address this issue, we proposed a minimally invasive approach for obtaining blood glucose measurements. In our proposed approach, the continuous glucose monitoring data of a third person are mapped to more sparse data from a particular user, acquired through traditional invasive means. The complete ensemble empirical mode decomposition with adaptive noise (CEEMDAN) method is then applied to the mapped glucose data. The first six intrinsic mode functions are discarded, and a long short-term memory (LSTM) network is used to perform non-invasive blood glucose estimation. To demonstrate the effectiveness of our proposed method, a loss function was used as a performance metric. Our approach was compared to the LSTM network, both with and without an empirical mode decomposition (EMD) approach.
Results Numerical simulation results showed that our approach achieved a higher accuracy than either of these two popular methods.
Conclusions Our method can be used to improve the accuracy of blood glucose prediction.
Study on the Characteristics of Overburden Rock Structure and Support System of the Retraction Channel in Layered Fully Mechanized Caving Face
Authors: Song Weihua , Yu Shiqi , Rong Hai , Jiao Huice , Xu Xiaotian 
Published: July 2023

Abstract
In response to the frequent disturbance of the dynamic pressure of the regenerated roof and the technical problems of controlling the stability of the roadway in the process of forming a large cross-section support withdrawal channel during the expansion of the layered fully mechanized caving working face under layered mining, taking the 1200-2 fully mechanized caving working face of Baiyinhua No.4 Mine as the engineering background,analyzed the load characteristics of the overlying rock structure and the top plate of the retractable passage after the expansion of the lower layered fully mechanized top coal caving face, and studied the combined support scheme of anchor rod, metal mesh, steel ladder belt, I-steel inserted beam, suspension beam, anchor cable, and single pillar, forming a safe and efficient construction support technology system,Practice has shown that this plan can effectively reduce the subsidence of the roof, narrow the range of plastic failure zone, ensure the stability of the surrounding rock of the tunnel during the support withdrawal period, and successfully complete the efficient withdrawal of the hydraulic support. The research results can provide good reference for roof management and the smooth production of coal resources after slope expansion under similar conditions.
Three times more than money: generativity, relational goods and life satisfaction
Authors: Becchetti Leonardo , Cermelli Massimo , Rosa Dalila 
Published: July 2023

Abstract

Generativity and the quality of relational goods are two key drivers of subjective well-being traditionally neglected in the economic literature. By using two different data sources (European Social Survey and EU-Silc), we investigate their impact on life satisfaction of two large samples of Italian individuals. Our findings show that their impact is positive and significant and, in both estimates from the two different data sources, a change from the lowest to the highest level of relational life has an impact three times higher than the change from the lowest to the highest income decile.
Relationship between Psycho-physiological Indicators and Task Performance under Various Indoor Space Designs for Telecommuting Environment by Introducing Mixed-Reality
Authors: Lee Kyung-Tae , Kim Ju-Hyung 
Published: July 2023

Abstract
The increase in telecommuting during COVID-19 and advances in digital technology have necessitated the establishment of guidelines for maximizing productivity through indoor space design for telecommuters. Additionally, understanding the physiological response of individuals working in indoor spaces has attracted attention. This study applied mixed-reality environment to alter the design of the indoor space in real-time, while monitoring the task performance and representative psycho-physiological indicators (electroencephalogram and heart rate variability) of 30 individuals with telecommuting experience. To this end, four tasks, including spatial memory, attention, execution, and working memory, were conducted, and the psycho-physiological data from these tests were statistically analyzed. The results revealed that the design of the indoor space did not affect the spatial memory; however, the parasympathetic nerves were stimulated in visually non-preferred spaces, thus reducing mental stress and leading to high efficiency in short-term work. According to the Yerkes-Dodson law, the working memory of an individual is generally efficient and physically stable over time if they adjust to a preferred or decision-making space. Thus, the future design of telecommuting spaces must consider the type of work being done, and guidelines for spatial design should be developed by recognizing the psycho-physiological status of users, while increasing efficiency.
Establishment of amygdalin antitumor efficacy against human acute monocytic leukemia cell line (THP‐1) with antimicrobial investigations, in vitro Study
Authors: Abdel-Gawad Doaa R.I. , Ibrahim Marwa A , El-Banna Hossny A. , Hassan Walid H. , Abdel-Gawad Ismail 
Published: July 2023

Abstract
Leukemia is an incurable disease; it exhibits strong resistance to chemotherapy and other therapies, its seriousness is not only in this fact but also, it represents the most common childhood cancer, and mortality. In this study, the cytotoxic of amygdalin (AMG) against the cell line of human monocytic leukemia (THP-1) was recoded in attempting for providing a cure for such monster cancerous type, be siding determining other pharmacological effects as anti-microbial activity. The cells were exposed to Vit b17 for 24 hr at 37°C at different concentrations, the cytotoxic effect was determined via the MTT assay. The cells and the supernatant were collected for analyzing the oxidant/antioxidant status, apoptotic markers, and anti-microbial activity. The results showed a marked anti-proliferative cytotoxic effect of Vit b17 which is concentration and time-dependent, the lipid peroxidation content was significantly decreased while the total thiol was significantly increased in the treated cell line, significant up-regulation of the transcript level of Caspase-3 (Cas-3) and Bcl-2-associated X protein (Bax) and down-regulation of B-cell lymphoma 2 (BCL-2). Furthermore, The bacterial activity was detected via Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC), and Disc Diffusion assays, while the antifungal evaluation was done by the Minimum Fungicidal Concentration (MFC). Antimicrobial experiments revealed that AMG exerted potent, broad-spectrum antimicrobial effects towards a diversity of dangerously infected pathogens. In conclusion, the prevailing research suggests that AMG is an effective antibacterial substance against a wide range of microbial pathogens that cause disease, in addition to its anticancer activity against human monocytic leukemia.
Influence of Advanced Glycation End-Products on Salivary Matrix Metalloproteinase 1 Levels in Chronic Periodontitis Patients with Type II Diabetes Mellitus
Authors: AHSAN AREESHA , SHAHID ABDUL MANAN , Qureshi Ali Waqar , Rehman Ambreen , Hassan Sobia , Shafiq Seema , Ismail Waleed Ahmed , Alam Mohammad Khursheed 
Published: July 2023

Abstract
Objective: This study was undertaken to assess whether advanced glycation end-products had any influence on the levels of matrix metalloproteinase-1 in patients with type-II diabetes mellitus and chronic periodontitis.
Material & Methods: It was a case-control study. 30 subjects were recruited in test group, who had chronic periodontitis and known cases of type-II diabetes mellitus. 30 subjects were kept in control group, who had chronic periodontitis but no systemic diseases. Periodontal parameters were recorded, samples of saliva were collected for all the subjects, and assessment of matrix metalloproteinase-1 levels was undertaken via enzyme linked immunosorbent assay. Statistical analysis was done using SPSS 26.
Results: The levels of matrix metalloproteinase-1 showed a significant elevation in test group in comparison to the controls (p<0.001). Likewise, all the periodontal parameters had greater readings in the test group as compared to the controls (p<0.05).
Conclusions:As there is a significant increase in the levels of salivary matrix metalloproteinase-1 due to advanced glycation end-products, as released in diabetic subjects, the destruction of periodontal apparatus was also, in return, greater in the diabetic subjects as compared to non-diabetic ones. This proves that advanced glycation end-products further elevate the levels of matrix metalloproteinase-1 in humans, resulting in greater destruction of periodontium.
Clinical Relevance:This study observes that if MMP-1 is inhibited by tissue inhibitors of metalloproteinases (TIMPs), the periodontal destruction in patients of type-II diabetes mellitus can be controlled and vice versa.
Building a Relevance Feedback Corpus for Legal Information Retrieval in the Real-Case Scenario of the Brazilian Chamber of Deputies
Authors: Vitório Douglas , Souza Ellen , Martins Lucas , Silva Nádia F. F. da , de Carvalho André Carlos Ponce de Leon , Oliveira Adriano L. I. , de Andrade Francisco Edmundo 
Published: July 2023

Abstract

The proper functioning of judicial and legislative institutions requires the efficient retrieval of legal documents from extensive datasets. Legal Information Retrieval focuses on investigating how to efficiently handle these datasets, enabling the retrieval of pertinent information from them.
Relevance Feedback, an important aspect of Information Retrieval systems, utilizes the relevance information provided by the user to enhance document retrieval for a specific request. However, there is a lack of available corpora containing this information, particularly for the legislative scenario. Thus, this paper presents Ulysses-RFCorpus, a Relevance Feedback corpus for legislative information retrieval, built in the real-case scenario of the Brazilian Chamber of Deputies. To the best of our knowledge, this corpus is the first publicly available of its kind for the Brazilian Portuguese language. It is also the only corpus that contains feedback information for legislative documents, as the other corpora found in the literature primarily focus on judicial texts. We also used the corpus to evaluate the performance of the Brazilian Chamber of Deputies' Information Retrieval system. Thereby, we highlighted the model's strong performance and emphasized the dataset's significance in the field of Legal Information Retrieval.
Improved DV-Hop Model Based on theApplication of Variable Scenarios
Authors: Wang Zhongsheng , Shen Han , Zhou Zhou 
Published: July 2023

Abstract
This work proposes an improved DV-Hop model based on function analysisand simulation parameter determination (named FuncDV-Hop) to address theproblems of low positioning accuracy and strong scene dependence of the DV-Hop localization model. The undetermined coefficient optimization, step functionsegmentation experiment, weight function strategy with equivalent points, andmaximum likelihood estimation correction are introduced to reduce the positioning error by analyzing the error reasons in the average hop distance, distanceestimation, and least square calculation of the DV-Hop model. The experiment isdesigned using the control variable method. The total number of nodes, the ratioof beacon nodes, the communication radius, the number of beacon nodes, and thenumber of unknown nodes are designed as variables to control the experiment.Finally, the experiments of two stages of simulation parameter determinationand integration optimization are carried out. The simulation optimization rateof all scenes is between 23.70% and 75.76%, and the average optimization rateis 57.23%. Experimental results show that the FuncDV-Hop model has the highest optimization rate of more than 50% in all experimental scenarios comparedwith the other models, the localization error is reduced by more than 0.1, andthe optimization rate is increased by more than 10% in the record parameters ofthe existing wireless sensor network system.
Tea grounds inspiration for a renewable biomass-based carbon aerogel with CMC and PVA reinforcements: Dye adsorption and supercapacitor prospects
Authors: Buu Ton That , Tu Phan Minh , Cong Che Quang , Hai Nguyen Duy , Minh Dang Thanh Cong , Nam Nguyen Thanh Hoai , Quan Vo Minh , Ngoc Bo Khanh , Han Le Gia , Ha Huynh Ky Phuong , Son Nguyen Truong , Hieu Nguyen Huu 
Published: July 2023

Abstract
In this study, tea grounds-carbon aerogel (TG-CA) was successfully synthesized and applied effectively in organic dye adsorption and supercapacitor applications. Interestingly, the prepared material has unique properties due to the synthesis process with the combination of carboxymethyl cellulose and poly(vinyl alcohol), which can improve the mechanical properties, strengthen the three-dimensional structure, and increase the specific surface area. Besides, the fabricated carbon aerogel also demonstrated excellent adsorption capacity for rhodamine B (RhB), crystal violet (CV), and methyl orange (MO) of 158.4, 143.2, and 132.9 mg/g for 2 h, respectively. Wherein, the adsorption efficiency of RhB dye was evaluated according to the pseudo-second-order kinetic (PSO) and the Langmuir isotherm model with R2 = 0.9947. Besides, the thermodynamic investigation of RhB adsorption using TG-CA800 reveals that the process is endothermic and the negative values of Gibb's free energy (ΔG°) demonstrate that the process was spontaneous. Regarding the electrochemical properties, the tea grounds-carbon prepared at 800oC (TG-CA800) indicated the highest specific capacitance of 291 F/g at the current density of 10 A/g with the potential window of −1.0 to 0 V in phosphate buffer (pH 7). Additionally, the great stability of the material was also confirmed with high capacitance retention of 97.53% after 500 cycles. These results suggest that the carbon aerogel materials prepared from green precursor sources, particularly tea grounds, could be considered a potential and promising approach to tackle organic dye elimination and supercapacitor applications.
Distribution, Etiology and Myocardial deformation imaging by speckle-tracking echocardiography in Valvular heart disease: A sub-analysis from a Clinical Registry
Authors: Nayak Asmitha G , Nayak Krishnananda , Manjoosha M , Ashwal A J 
Published: July 2023

Abstract
Purpose Valvular Heart Disease (VHD) has been a major contributor of global cardiovascular morbidity and mortality with increasing need of percutaneous/surgical cardiac intervention. Strain echocardiography has been widely recognizable tool to guide the timings of interventions in these patients. The purpose of this study was to document the demographic, clinical signs and symptoms, Electrocardiographic and Echocardiographic parameters in different groups of VHD as well as to assess Left ventricular and right ventricular function in specific groups of VHD.Methods All patients with valvular heart disease who visited a tertiary care hospital in Karnataka during the study period were included in the registry. However, for the study purpose VHD with a severity of at least more than or equal to moderate and with preserved Left ventricle ejection fraction (LV EF) were included for the analysis. Basic demographic, clinical, electrocardiographic, standard echocardiographic and strain parameters were obtained and evaluated.Results During the study period of 10 month a total number of 5,271 subjects had VHD (excluding the presence of trivial or mild functional regurgitant lesion). The most commonly occurring single valvular disease was mitral regurgitation (31%) followed by aortic stenosis (15%) and aortic regurgitation (13%). Rheumatic heart disease (RHD) was the dominant etiology (32.8%) for VHD followed by degenerative heart disease (31.3%). Deformation imaging by 2D speckle-tracking echocardiography was preserved for left ventricle (LV) but mildly reduced for right ventricle (RV).Conclusion MR was the most common valvular lesion followed by AS and AR. Rheumatic disease still prevails as the major precursor. Ventricular remodelling varied depending on the lesion type.