bluuebunny/crossref_metadata_2025_split huggingface dataset:
Barossa be consumed: a semiotic smorgasbord for Southeast Asians
Authors: Shaw Michael , Bandara Priyantha , Khan Sardana Islam 
Published: April 2023

PurposeThis study is an attempt to apply the techniques of semiotics in conjunction with quantitative analysis to decode and interpret an advertisement which promotes the South Australian Barossa Valley as a tourist destination.Design/methodology/approachA survey was submitted to a Southeast Asian student and postgraduate sample. Regression analysis and qualitative analysis were carried out, which suggested that the advertisement was engaging the majority of the audience.FindingsMost respondents expressed a desire to visit the location and used language which was evocative and connective. Those who did not or who were turned off by the advertisement's content expressed themselves in language which terminated further engagement.Research limitations/implicationsThe sample was a non-target group, but this is an advantage because it provides a base level of unconditioned response.Practical implicationsA better understanding of semiotics may reinforce other areas of marketing endeavour such as social marketing approaches which are gaining more importance in the still developing COVID-19 economy. This methodology can be extended to other marketing communication contexts.Social implicationsOnce campaigns have been aimed at target audiences, there may be potential to orientate another campaign at non-target audiences using the same advertisement. In terms of global marketing, this is extension rather than adaptation.Originality/valueThis study provides an example of how marketing could use semiotics in conjunction with quantitative methods to determine an audience's response and the intention to purchase a product or service.
Upscaling method based on sedimentary cycle prior and its application to well‐to‐seismic tie
Authors: Tian Yajun , Stovas Alexey , Gao Jinghuai 
Published: April 2023

AbstractA well‐to‐seismic tie is a typical upscaling problem. The traditional well‐to‐seismic tie methods often use the velocity log directly to tie well logs to seismic data without considering the upscaling problem led by the velocity dispersion due to thin beds. We propose an upscaling method based on the Backus average method to upscale the well‐log velocity to seismic velocity and apply it to a well‐to‐seismic tie problem. For Backus average method, choosing an appropriate average window is a crucial issue. We introduce a synchrosqueezing optimal basic wavelet transform to calculate an average window. The synchrosqueezing optimal basic wavelet transform is a time–frequency representation method, which can extract the sedimentary cycle information from seismic data. Considering the relationship between the sedimentary cycle and the thin‐bed thickness, we propose a workflow to estimate the instantaneous thin‐bed thickness based on synchrosqueezing optimal basic wavelet transform and determine the window length of the Backus average at each depth point. Then, the Backus average is used to estimate the effective velocity, which is further used to calculate the initial time–depth function and transfer the reflection coefficients from the depth domain to the time domain. Choosing an appropriate seismic wavelet is another fundamental problem for the well‐to‐seismic tie process. This paper introduces an alternating iterative deep neural network‐based method to estimate the seismic wavelet. Thus realistic synthetic seismograms can be computed by convolving the estimated seismic wavelet and the reflection coefficient, which can be stretched or squeezed to match the near‐well seismic trace. We show that the proposed workflow effectively reduces the errors in a well‐to‐seismic tie procedure caused by velocity dispersion of thin beds.
Temporal sweet taste dominance according to adult body mass index classification
Authors: Lima Rafael Sousa , Ramos Lizandra Mesquita , de Medeiros Sousa Vinícius , Tonucci Livia Bordalo , Pereira Cecília Teresa Muniz , Pereira Dalva Muniz , de Medeiros Alessandra Cazelatto , Bolini Helena Maria André 
Published: April 2023

AbstractExcess adipose tissue is associated with basic tastes perception change, which can negatively affect food choices. However, the effect of overweight and obesity on sensory perception is not clearly explained in the literature yielding heterogeneous results. The present investigation aimed to investigate the temporal dominance of sweet taste according to body mass index (BMI) classification in adults during the ingestion of five passion fruit nectar samples prepared with different sucrose concentrations. The temporal dominance of sensations methodology was applied, which allowed the representation of the stimuli assessed in dominance curves, considering a significant difference in Fisher's exact test (p ≤ 0.05). The attributes evaluated were sweet taste, bitter taste, acidic taste, astringency, passion fruit flavor, metallic taste, or none of the previous options. The sensory analysis was performed with the participation of ninety adult consumers, divided into three groups: EG = eutrophic, WG = overweight, and OG = obesity group, according to the BMI classification. Between the groups a difference in the perception of the attribute “sweet taste” was observed: The EG demonstrated perception of the stimulus in food samples at lower sucrose concentrations, whereas WG and OG showed a higher rate of sweet taste dominance in the food samples with higher concentration of sucrose. Overweight and obese individuals have a lower sensory perception of sweet taste and require a greater amount of sucrose to producing sensory dominance of the attribute “sweet taste” when compared to eutrophic individuals.Practical ApplicationOverweight and obese individuals may experience taste perception in foods in a different way. This study investigated the dominance of sweet taste perception in a fruit beverage by adults with adequate weight and overweight. The results of the tests support the hypothesis that obese and nonobese individuals differ in the sweet taste perception, which can help to understand which factors are involved in sensory perception and food consumption, in addition to providing subsidies for the nonalcoholic beverage industry to elaborate products with new alternatives for concentration and/or replacement of sucrose.
Saving the world through private‐sector efficiency and local empowerment? Discursive legitimacy construction for social entrepreneurship in the Global South
Authors: Katzer Eva , Sendlhofer Tina 
Published: April 2023

AbstractIn efforts to achieve the Sustainable Development Goals, social entrepreneurship has gained popularity as a vehicle for positive change in developing countries. The multiplicity of stakeholders, diverging sociocultural contexts and the hybrid mission complicate the process of legitimacy construction for social entrepreneurs as a basis for the acquisition of scarce resources. This study investigates how social entrepreneurs operating in Sub‐Saharan Africa and Asia tackle this challenge of bridging conflicting directions in discursive interaction with their European funders. We conduct a multimodal discourse analysis to uncover discursive strategies for legitimacy construction by combining linguistic data from interviews with visual data from social media accounts. Legitimacy construction, and thus resource acquisition, centers on three aspects which interlink pragmatic, cognitive and moral legitimacy: developing innovative solutions, mobilizing private‐sector efficiency, and contributing to local empowerment. Presenting these aspects as mutually reinforcing overcomes contradictions between social and business logics and provides an expanded space for legitimacy construction of social entrepreneurship. Discursively constructing legitimacy around a ‘glorified version of social entrepreneurship’ mobilizes resources but downplays the risk of being an entrepreneur in the Global South, contributing to increasing corporatization of social purpose organizations.
Genetic mixing facilitates adaptation to a novel environmental constraint
Authors: Durkee Lily F. , Olazcuaga Laure , Szymanski Rachael , Melbourne Brett A. , Hufbauer Ruth A. 
Published: April 2023

AbstractClimate change can affect the length and timing of seasons, which in turn can alter the time available for insects to complete their life cycles and successfully reproduce. Intraspecific hybridization between individuals from genetically distinct populations, or admixture, can boost fitness in populations experiencing environmental challenges. Admixture can particularly benefit small and isolated populations that may have high genetic load by masking deleterious alleles, thereby immediately increasing fitness, and also by increasing the genetic variation available for adaptive evolution. To evaluate the effects of admixture on populations exposed to a novel life cycle constraint, we used the red flour beetle, Tribolium castaneum, as a model system. Distinct laboratory lineages were kept isolated or mixed together to create populations containing 1–4 lineages. We then compared the fitness of admixed populations to 1‐lineage populations while subjecting them to a shortened generation time for three generations. Admixture did not influence fitness after two generations. In contrast, in the third generation, admixed populations had significantly greater fitness compared with 1‐lineage populations. The timing of the increase in fitness for the admixed populations suggests that adaptation to the novel environmental constraint occurred in the experimental populations. Our study highlights the importance of admixture for facilitating rapid adaptation to changes in seasonality, and more broadly to environmental change.
Molar–incisor hypomineralisation in Norwegian children: Prevalence and associated factors
Authors: Haque Afzal Sadaf , Wigen Tove Irene , Skaare Anne Berit , Brusevold Ingvild Johnsen 
Published: April 2023

AbstractThis study investigated the prevalence and associations of molar–incisor hypomineralisation (MIH) in 8–9 year‐old children in Oslo. A total of 3013 children in one age cohort participated in the study during their regular dental examination at the Public Dental Service. Hypomineralised enamel defects were recorded according to the European Academy of Paediatric Dentistry criteria for MIH. Information on health and medications used during pregnancy and in the child's first 3 years of life was obtained from a questionnaire administered to parents. The overall prevalence of MIH was 28.2%, with no gender difference. A higher prevalence of MIH was found in children who had been ill or had used medication in early life and in those whose mother had been ill during pregnancy. No association was found between MIH and prematurity or maternal use of medication during pregnancy. The multivariable analyses showed that children with MIH were more likely to have suffered from illness in early life (OR = 1.41, 95% CI: 1.17–1.70), used antibiotics during the first year of life (OR = 1.68, 95% CI: 1.19–2.35), experienced tooth pain (OR = 1.33, 95% CI: 1.03–1.72), and experienced pain while toothbrushing (OR = 2.17, 95% CI: 1.46–3.23) than children without MIH. The prevalence of MIH was high in the children participating in this study.
Transgenerational effect on sexual reproduction in rotifer populations in relation to the environmental predictability of their habitats
Authors: Colinas Noemi , Carmona María J. , Serra Manuel , García‐Roger Eduardo M. 
Published: April 2023

Abstract

One way to cope with predictable environmental fluctuations that affect several generations of individuals is through nongenetic transgenerational effects. Ancestors match the phenotype of their descendants to the environment the latter are expected to experience. In facultatively sexual rotifer life cycles, sex is linked to the production of diapausing eggs, which enables survival between growing seasons. In some rotifer species, sexual reproduction is inhibited several generations after diapausing eggs hatch. We hypothesised that in ponds where the growing season length is predictable, rotifer clones reproduce asexually for more generations, allowing a fuller exploitation of the growing season and maximising production of diapausing eggs at the end of the season.

We tested this prediction by estimating the proportion of sexual females produced by several clones of the rotifer Brachionus plicatilis inhabiting eight ponds that vary in the predictability of the length of their growing season.

Rotifer clones from more predictable ponds were unresponsive to cues that induce sexual reproduction for more generations after leaving diapause than clones from unpredictable ponds. However, clones from more unpredictable ponds did respond to these cues from early generations, probably as a way to ensure the production of diapausing eggs against the risk of an unexpectedly early end to the growing season. Significant within‐population clonal variation was observed in transgenerational responses.

Our results showed that the transgenerational inhibition of sexual reproduction observed in B. plicatilis evolved in clones from habitats where the length of the growing season (i.e., the period when populations are active in the water column) is more predictable on an interannual scale. Our findings also suggest that the longer the growing season, the more prolonged the inhibition effect (i.e., it affects a greater number of asexual generations).

This research shows the importance of understanding how organisms adapt to fluctuating environments through transgenerational strategies and establishes the groundwork for future studies of the regulatory mechanisms underlying the transgenerational modulation of sex in rotifers.
Stochastic resonance in climate reddening increases the risk of cyclic ecosystem extinction via phase‐tipping
Authors: Alkhayuon Hassan , Marley Jessa , Wieczorek Sebastian , Tyson Rebecca C. 
Published: April 2023

AbstractHuman activity is leading to changes in the mean and variability of climatic parameters in most locations around the world. The changing mean has received considerable attention from scientists and climate policy makers. However, recent work indicates that the changing variability, that is, the amplitude and the temporal autocorrelation of deviations from the mean, may have greater and more imminent impact on ecosystems. In this paper, we demonstrate that changes in climate variability alone could drive cyclic predator–prey ecosystems to extinction via so‐calledphase‐tipping(P‐tipping), a new type of instability that occurs only from certain phases of the predator–prey cycle. We construct a mathematical model of a variable climate and couple it to two self‐oscillating paradigmatic predator–prey models. Most importantly, we combine realistic parameter values for the Canada lynx and snowshoe hare with actual climate data from the boreal forest. In this way, we demonstrate that critically important species in the boreal forest have increased likelihood of P‐tipping to extinction under predicted changes in climate variability, and are most vulnerable during stages of the cycle when the predator population is near its maximum. Furthermore, our analysis reveals thatstochastic resonanceis the underlying mechanism for the increased likelihood of P‐tipping to extinction.
Association of proton pump inhibitor and antibiotic use with the clinical outcomes of hepatocellular carcinoma patients receiving atezolizumab and bevacizumab: A multicenter analysis
Authors: Hatanaka Takeshi , Kakizaki Satoru , Hiraoka Atsushi , Tada Toshifumi , Hirooka Masashi , Kariyama Kazuya , Tani Joji , Atsukawa Masanori , Takaguchi Koichi , Itobayashi Ei , Fukunishi Shinya , Tsuji Kunihiko , Ishikawa Toru , Tajiri Kazuto , Ochi Hironori , Yasuda Satoshi , Toyoda Hidenori , Ogawa Chikara , Nishimura Takashi , Shimada Noritomo , Kawata Kazuhito , Kosaka Hisashi , Naganuma Atsushi , Yata Yutaka , Tanaka Takaaki , Ohama Hideko , Tada Fujimasa , Nouso Kazuhiro , Morishita Asahiro , Tsutsui Akemi , Nagano Takuya , Itokawa Norio , Okubo Tomomi , Arai Taeang , Imai Michitaka , Koizumi Yohei , Nakamura Shinichiro , Kaibori Masaki , Iijima Hiroko , Hiasa Yoichi , Kumada Takashi ,   Real‐life Practice Experts for HCC (RELPEC) Study Group, and HCC 48 Group (hepatocellular carcinoma experts from 48 clinics in Japan)
Published: April 2023

AbstractAimThis retrospective study aimed to investigate the impact of proton pump inhibitor treatment (PPI) and antibiotic treatment on the therapeutic outcomes of hepatocellular carcinoma (HCC) patients receiving atezolizumab and bevacizumab (Atez/Bev).MethodsThe present study included a total of 441 HCC patients who were treated with Atez/Bev in 20 Japanese institutions from September 2020 to April 2022. We adopted the inverse probability of treatment weight to adjust for imbalance in the baseline characteristics of patients with and without PPI treatment as well as patients with and without antibiotic treatment.ResultsThe progression‐free survival (PFS) and overall survival (OS) of patients with and without PPI treatment did not differ to a statistically significant extent. In the weighted cohort, the difference in PFS and OS between the patients with and without PPI did not reach statistical significance (median PFS, 7.0 vs. 6.5 months, p = 0.07; 1‐year survival rate 66.3% and 73.8%, p = 0.9). The PFS and OS in patients with antibiotic treatment were worse in comparison to patients without antibiotic treatment (median PFS, 3.8 vs. 7.0 months, p = 0.007; 1‐year survival rate 58.8% and 70.3%, p = 0.01). In the weighted cohort, the PFS and OS of the two groups did not differ to a statistically significant extent (median PFS, 3.8 vs. 6.7 months, p = 0.2; 1‐year survival rate, 61.8% and 71.0%, p = 0.6).ConclusionsThe therapeutic outcomes of Atez/Bev in HCC patients did not differ between patients with and without PPI treatment or between patients with and without antibiotic treatment.
Eco‐anxiety and environmental sustainability interest: A secondary data analysis
Authors: Chung Sophia J. , Jang Sun Joo , Lee Haeyoung 
Published: April 2023

AbstractClimate change is an increasingly important global concern, requiring urgent action. To achieve environmental sustainability, identifying the predictors influencing individuals' actions is necessary. Individuals with negative psychological responses to climate change, such as eco‐anxiety, are more likely to engage in pro‐environmental behaviour. However, eco‐anxiety and other perceptions associated with climate change and sustainability can differ based on an individual's unique background. Therefore, this study aimed to identify potent predictors of individuals' environmental sustainability interest and examine the impact of eco‐anxiety on environmental sustainability interest. Data from 459 South Korean adults (19–65 years) were included in this secondary analysis. Eco‐anxiety, climate change risk perception and future event cognition were assessed by the Climate Change Anxiety Scale, the Climate Change Risk Perception Inventory and Future Event Questionnaires, respectively. Multiple linear regression analysis showed that eco‐anxiety was the most potent predictor of environmental sustainability interest, followed by climate change risk perception, age 60–65 years, future event cognition and age under 30 years. Considering that eco‐anxiety is the most potent predictor of environmental sustainability interest, mental health nurses should assess patients' eco‐anxiety level and help them recognize and manage their anxiety levels appropriately. Age‐specific approaches should be considered for interventions to enhance environmental sustainability interest. Further studies are needed to determine the cut‐off anxiety level that influences the positive impact on environmental sustainability interest and to develop programmes to manage eco‐anxiety.
Determinants of bank capital adequacy: International evidence from G7 countries
Authors: Кishibayeva Botagoz , Jaxybekova Galiya , Nurgalieva Gulnar , Wada Isah , Faizulayev Alimshan 
Published: April 2023

AbstractThe study presents the determinants of bank capital for the G7 countries from 1999 to 2017. It employs a dynamic ordinary least square panel methodology for empirical estimation. The findings suggest that bank capital to total asset, bank z‐score and the real output growth are positive determinants of bank regulatory capital. Conversely, bank return on assets is found to be a negative determinant. After constructing an index for profitability using the approach of the component analysis, the empirical result reveals an inverse relationship between bank profitability and the regulatory minimum capital. Diagnostic tests and robustness checks confirm the empirical consistency of the findings reported. Thus, in applying the panel pairwise causality test, the evidence of bi‐directional Granger causality suggests a feedback relationship for five significant scenarios and unidirectional nexus in others. For policy consideration, the results stressed the need for optimal due diligence weighing the benefit and cost implication of upward or downward adjustment of bank regulatory minimum capital.
Guided Wave Damage Location of Pressure Vessel Based on Optimized Explainable Convolutional Neural Network for Multivariate Time Series Classification Neural Network
Authors: Zhang Junxuan , Hu Chaojie , Yan Jianjun , Hu Yue , Gao Yang , Xuan Fuzhen 
Published: April 2023

Abstract
Guided wave is a key nondestructive technique for structural health monitoring due to its high sensitivity to structural changes and long propagation distance. However, to achieve high accuracy for damage location, large quantities of samples and thousands of iterations are typically needed for detection algorithms. To address this, in this paper, an eXplainable Convolutional neural network for Multivariate time series classification (XCM) is adopted, which is composed of one-dimensional (1D) and two-dimensional (2D) convolution layers to achieve high accuracy damage location on pressure vessels with limited training sets. By further optimizing the network parameters and network structure, the training time is greatly reduced and the accuracy is further improved. The optimized XCM improves the damage location precision from 95.5% to 98% with small samples (training set/validation set/testing set = 23/2/25) and low training epochs (under 100 epochs), suggesting that the XCM has great advantages in pressure vessel's damage location classification its potential for guided wave-based damage detection techniques in structural health monitoring.
In Vivo
Pharmacodynamic Profile of EVER206, a Novel Polymyxin Antimicrobial, against Gram-Negative Bacteria in the Murine Thigh Infection Model
Authors: Gill Christian M. , Nicolau David P. 
Published: April 2023

The objective was to determine the magnitude of the EVER206 free-plasma area under the concentration time curve (
f
AUC)/MIC target associated with bacteriostasis and 1-log
10
kill against clinically relevant Gram-negative bacteria in the murine thigh model. Twenty-seven clinical isolates (
Pseudomonas aeruginosa
,
n
= 10;
Escherichia coli
, n
= 9;
Klebsiella pneumoniae
,
n
= 5;
Enterobacter cloacae
,
n
= 2; and
Klebsiella aerogenes
,
n
= 1) were tested.