bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimization of Hydrophobic Lime Putty Enriched with Sesame Oil for In-situ Preparation of Restoration Mortars
Authors: Pahlavan Parsa 
Published: August 2023

Abstract
The use of organic fatty acids as additives in historic mortars presents a technical challenge, particularly when oils need to be added on site. This study presents a solution to this problem by formulating hydrophobic lime putty enriched with sesame oil and evaluating air lime mortars containing the new lime putty. The results show that the mortars containing the new lime putty exhibit substantial hydrophobic effects that are comparable to those of mixes with conventional lime putty and additive oil. The soundness of the oiled lime putty was confirmed 12 months after synthesis, demonstrating its long-term viability. The proposed method offers a feasible approach for in-situ applications and contributes to the preservation of historic masonry structures.
A Small and Highly Efficient Four-Element Antenna for Modern Wireless Applications
Authors: Krishnamoorthy R. , Balaram Allam , Kumar Ushus S. , Kapali B Suresh Chander , Sagar K. V. Daya , Nancharaiah B 
Published: August 2023

Abstract
This article discusses a compact and versatile quad-port dual-band printed antenna designed for 5G, V2X, and WLAN/Wi-Fi 6E applications. The antenna is printed on a 75mm x 75mm FR4 substrate with a thickness of 1.6mm. It operates efficiently within the 5G spectrum (3.2–3.8 GHz) and the upper WLAN band (5.2–6.86 GHz) with a 10 dB impedance bandwidth. The proposed antenna covers a wide range of current and future frequency bands for 4G and 5G applications, making it highly versatile. Despite keeping the antenna components at a minimum distance, it achieves excellent isolation performance, exceeding 13 dB. This results in a high radiation efficiency of 89% and substantial gain of approximately 4.8 dBi across the applicable range. In order to assess the performance of Multiple-Input Multiple-Output (MIMO) systems, several metrics including Envelope Correlation Coefficient (ECC), channel capacity and Channel Capacity Loss (CCL) were computed, according to the specifications outlined in the MIMO standard. After thorough examination, the suggested antenna is found suitable for applications involving broad and multiple frequency bands.
Do socio-economic factors impact non-timber forest products based incomes: an analysis employing structural equation modelling (SEM); a case of India
Authors: Magry Muneer Ahmad , Cahill David , rookes James , Narula Sapna 
Published: August 2023

Abstract
The examination of the use pattern of Non-Timber Forest Products (NTFPs) and their contribution in connection to socioeconomic determinants is crucial for the formulation of welfare and development efforts targeted at communities reliant on NTFPs. A study was conducted in the Khunti district of Jharkhand, India, including 62 villages and involving a total of 387 respondents. The survey was conducted using structured questionnaires. Additionally, focused group discussions and transect walks were conducted to supplement the results. The findings indicated that a majority of the individuals involved in the upstream activities are female, accounting for 70% of the total population. The income derived from non-timber forest products (NTFP) was influenced by many factors including socioeconomic, ecological, and demographic variables as determined by five capital evaluations. The results indicate that individuals get a substantial proportion of their earnings from the collection of non-timber forest products (NTFPs). Nevertheless, the degree and distribution of household income dependence on NTFPs exhibit notable variations across different socioeconomic and demographic characteristics. The intensity of non-timber forest product (NTFP)-based income in families is influenced by several factors including women's roles, education level, age, landholding, household size, and the number of children. It is determined that the incorporation of socio-economic-ecological and demographic factors is crucial in the development of a proficient forest management plan and policy for the management of non-timber forest products (NTFPs) and the preservation of forests. This necessitates the active participation of populations reliant on NTFPs.
Nanosilver For Anopheles Control In Endemic Malaria
Authors: Raharjo Mursid , Subagio Agus , Sulistiyani Sulistiyani 
Published: August 2023

Abstract
Malaria is a national and global problem that needs attention, with 241 million cases. Indonesia is the second highest country with the highest number of cases, with 304,607 cases of malaria in 2021. The use of insecticides at inappropriate doses causes resistance to targets. This study aimed to analyze the toxicity of silver nanoparticles to adult Anopheles mosquitoes in malaria-endemic areas, determine the lethal concentration (LC50), and project effectiveness in the long term. The calculation of LC50 is based on the estimation and plotting of observed data with the formula y = ax + b. LC50 in Nanosilver nitrate toxicity 5965 mg/l. Analysis of long-term projections with the formula y = A ln (x) + B produces the formula Y = (-) 0.012Ln(X) + 0.6933. Absorption of silver nanoparticles into the bodies of Anopheles sp. occurs through the spiracles. It attacks the Ache enzyme in the central nervous system, thereby stopping the mosquito's working system, which will then die. Nanosilver is a very effective herbal insecticide used in an effort to control malaria cases in endemic areas with the correct dose and method. For a lifetime, a dose of 1500 mg/l nanosilver effectively kills 74% of adult Anopheles sp mosquitoes on day 32 and it is projected that on day 60 the efficacy of nanomaterials still has an efficacy of 64% which then decreases to day 180 (6 months) with an efficacy of 63%. Even this nano silver material has an efficacy of 62% within 360 days (1 year).
Neuron stress-related genes serve as newbiomarkers in hypothalamic tissue following high fat diet
Authors: Duan Chengwei , Wang Xueqin , Su Jianbin , Qi Feng , Chen Tianpeng , Shang Yanxing , Liang Caixia , Li Yu , Su Sixuan , Zhang Dongmei , Lu Hongjian 
Published: August 2023

Abstract
Objective
Energy homeostasis is modulated by the hypothalamic is essential for obesity progression; however, the gene expression profiling remains to be fully understood.
Methods
GEO datasets were downloaded from the GEO website and analysed by the R packages to obtain the DEGs. And, the WGCNA analysis and PPI networks of co-expressed DEGs were designed using STRING to get key genes. In addition, the single-cell sequencing datasets and GTEx database were utilized to receive the neuron-stress genes from the key genes. Further, HFD-induced hypothalamic tissue of mice was used as an animal model to validate the mRNA up-regulation of neuron-stress genes. Finally, the Bmi1 gene was identified as a hub gene through the LASSO model and nomogram analysis.
Results
It found that six genes (Sacm1l, Junb, Bmi1, Erbb4, Dkc1, and Suv39h1) are neuron stress-related genes and increased in the HFD-induced mice obesity model. Finally, Bmi1gene was identified as hub genes that can reflect the pathophysiology of obesity.
Conclusions
Our research depicted a comprehensive activation map of cell abnormality in the obese hypothalamus and Bim1 may be a diagnostic marker in the clinic, which provides a new perspective and basis for investigating the pathogenesis of obesity.
SGLT2 inhibitors effects on cardiac function and plasma biomarkers of diabetic patients with preserved ejection fraction
Authors: García Marcelino Cortés , Gonzalez Oscar Lorenzo , Lumpuy-Castillo Jairo , Martínez-Albaladejo Sacramento , Urquía Mikel Taibo , Lázaro Ana María Pello , Becerra Jose Antonio Bollas , Orejas Miguel Orejas , Lobato Miguel Ángel Navas , Palafox Esther Macia , Fernández María Esther Martínez , Linares Andrea Rueda , Fernández Jose Tuñón 
Published: August 2023

Abstract
BACKGROUND
Sodium-glucose cotransporter inhibitors (SGLT2i) have proven a reduction in cardiovascular events in diabetic patients with and without heart failure (HF), as well as in non-diabetic patients with HF. The mechanisms underlying this benefit are not well known, with contradicting data on the changes that SGLT2i produce on cardiac function and structure.
METHODS
Between October 2020 and October 2021, 31 diabetic patients without prior history of SGLT2i use with normal ejection fraction (> 50%), glycated hemoglobin < 6.5%, renal clearance rate of > 60 ml/min/1.73 m2 and sinus rhythm were prospectively included. In all of them, SGLT2i were started. At inclusion and 6-months follow-up, different clinical, ECG, analytical and echocardiographic (standard, 3D and speckle tracking) variables were recorded.
RESULTS
The average age of our population was 66.4 years (± 8.4). 90% were male, 71% were hypertensive, and 77.4% were dyslipidemic. 77.4% of patients had a history of ischemic heart disease, and 10% had vascular disease in other territories. At the time of inclusion, 80.6% of the population was treated with ACEI or ARB, 54.8% with beta-blockers, 29% with diuretics, and 93.5% with statins. After an average follow-up period of 6.6 months (± 0.8), an average reduction of 9.9 g/m2 (± 4.5, p = 0.048) in 3D-estimated left ventricle mass was observed. An increase in absolute left ventricle global longitudinal strain (LVGLS) of 0.74 (± 0.35, p = 0.05) was observed, as well as an increase in isovolumetric relaxation time (IVRT) of 9.8 ms (± 4.8, p = 0.05). Moreover, we observed a significant reduction in ANP (p = 0.008) and CK-MB levels (p = 0.006), after SGLT2i treatment. No relevant differences in LV dimensions and volumes were observed, as well as in the evaluated RV parameters and other biomarkers.
CONCLUSIONS
It is necessary to understand the mechanism underlying the clinical benefit of these drugs. This will allow us to better understand its effect in patients with HF. Our data shows that the use of SGLT2i is associated with cardiac improvements, both structural (myocardial mass) and functional (IVRT, LVGLS), in a population of patients with normal ejection fraction.
Effectiveness of Fecal DNA Syndecan-2 Methylation Test in Detecting Colorectal Cancer in High-Risk Population in China
Authors: Luo Wenfeng , Lin Xiaoling , Jiao Yuting , Zhao Ying , Wang Shengbo , Shen Jian , Han Zeping , Xie Fangmei , He Jinhua , Wan Yu 
Published: August 2023

Abstract
Purpose:To validate the effectiveness of fecal DNA Syndecan-2 methylation (mSDC2) test in the detection of colorectal cancer in high-risk population in China. This may provide evidence-based data of diagnostic or screening for colorectal cancer in China.
Methods A high-risk Chinese pilot comprising 1130 individuals aged 40-79 was registered for colorectal cancer (CRC) detection using the fecal mSDC2 test. The sensitivity and specificity to CRC, advanced adenomas (AA), and advanced colorectal neoplasia (ACN) were estimated. High-risk factors for incidence of colorectal lesions were analyzed and then were constructed a logistic regression model to better reflect the efficacy of the fecal mSDC2 test.
ResultsAccording to established criteria, 1035 high-risk individuals were included for analysis. Among them, 16 CRCs (1.55%), 65 AAs (6.28%), 189 NAAs (18.26%), and 150 polyps (14.49%) were defined by colonoscopy and pathological examination. The sensitivity of mSDC2 test to CRC and AA was 87.50% and 40.00%. The specificities were 95.61% in the others group. The positive predictive value (PPV) of mSDC2 test for CRC, AA, and ACN was 16.09%, 29.89% and 45.98%, respectively. In addition, the negative predictive value (NPV) of mSDC2test for CRC was 99.79%. The positive of mSDC2 test is a significant risk signal for the occurrence of ACN (P <0.001) after adjusting other high-risk covariates.
ConclusionThe results of this CRC screening showed that offering a combination of fecal mSDC2test and colonoscopy may be an active option to early detect malignant lesions of the colorectum in Chinese high-risk population.
Fabrication of IR Microlens Using Fiber Laser
Authors: Mahmoud Muaath J. , Rasheed Basaam G. 
Published: August 2023

Abstract

Various types of silicon micro lenses were fabricated by two subsequent stages. Fiber laser of 1.06 µm was employed to ablate micro dips at the silicon surface then a mixed acid solution was used to ultrasonically etch the wafer. The experimental data demonstrate spherical, cylindrical IR microlenses, and IR microlens array formation with an optimum numerical aperture of 2.39. minimum microlens height of 21 µm, diameter of 32 µm, and focal length of 6.7 µm with maximum resolution of 0.395 µm and magnification of (X 44) was achieved. The minimum experimentally achieved micro lens’s roughness was 45 nm. Theoretical calculations were conducted to estimate the temperature at the silicon surface during the ablation stage. Temperature of approximately 3590 K is established at the center of the laser-silicon in the ablation stage. Due to the controllable laser micromachining process, optoelectronics and biological imaging are viable applications for IR microlens arrays.
Electromagnetic and Thermal Analysis of 4 Pole Induction Motors - A Design Outlook for IE3 to IE5 Efficiencies
Authors: Kishor Abhishek , Chokklaingam Lenin Natesan , Nandagopal Sathyanarayanan , Seshadri Arjun 
Published: August 2023

Abstract
India is working towards achieving sustainable development goals by 2030. One important goal of sustainable development is energy efficiency. Around 18% of total energy consumed in India is by agricultural pump sets. These pump sets are driven by induction motors. Thereby, design of induction motors meeting energy efficiency standards becomes the need of the hour. This paper provides a detailed design outlook for 3 phase, 4 pole, 50 Hz, induction motors between the power range of 11kW to 2.2kW to meet the IE3 to IE5 efficiency standards.
Effect of Si Addition in NiCrAl Coating on Corrosion in Molten Nitrate Salt
Authors: Kettrakul Patchaporn , Siripongsakul Thamrongsin , Kanjanaprayut Noparat , Wiman Panya , Promdirek Piyorose 
Published: August 2023

Abstract

The materials used in concentrating solar power (CSP) systems are becoming of interest because of high energy efficiency of energy storage. It can apply molten salts as heat storage media and heat transfer fluid in a CSP system. In molten salts, steel alloys such as vessels, pipe-lines, and heat exchangers are very vulnerable to hot corrosion. To protect steel alloys, coating is an excellent strategy to lengthen the service lifetime and reduce the maintenance cost. NiCrAl coatings are suitable candidates for a high temperature environment. Thus, this research aims to investigate the corrosion behaviour in molten salt of NiCrAl coatings on AISI304 stainless steel with Si addition in the coating. NiCrAl coatings with and without Si addition were deposited using the high-velocity oxygen fuel (HVOF) technique. The corrosion test was performed using the immersion test in the modified molten salt (solar salt + 0.5%NaCl) at 400, 500 and 600°C. The gravimetric method was used to evaluate weight change for the immersion test. At 400°C, more evident weight gain due to molten salt infiltration was observed rather than oxidation reaction. At 600°C, oxidation became more dominant and oxidation products NiO and sodium-aluminium-silicate were detected. Si addition resulted in supporting the formation of the protective oxide, sodium-aluminium-silicate which was acting as a blockade against molten salt infiltration. Furthermore pore spaces were replaced by the protective oxide in the coating surface. The reactions related to oxide formation and hot corrosion were further discussed.
Negative expression of CD117 predicted inferior OS and PFS in acute promyelocytic leukemia
Authors: Zeng Hui , He Jie , Dong Hai-Bo , Zhou Min , Zhang Qian , Chen Lan-Xin , Yuan Cui-Ying , Jiang Ru-Ru , Liu Jin-Wen , Ou-Yang Jian , Ben Yu , Chen Bing 
Published: August 2023

Abstract

Up to date, there are few reports on the clinical significance of CD117 antigen in acute promyelocytic leukemia (APL), especially CD117−APL. In this study, we retrospectively investigated the clinicopathological characteristics, outcome and prognostic effect of CD117 antigen negativity in 169 APL patients treated with ATRA-ATO regimen. The median follow-up period was 63.0 months. CD117− was found in 13 APL patients (7.7%). No significant differences were found in baseline characteristics between CD117+ and CD117− subgroups. Compared with CD117+ APL, the incidence of early death (ED) in CD117− APL was significantly higher (P = 0.023). By multivariate analysis, CD117 negativity was an independent adverse prognostic factor for overall survival (OS) and progression-free survival (PFS) (P = 0.040 and P = 0.030, respectively). In conclusion, negative CD117 expression is associated with greater risk of ED and has the statistical power to predict inferior OS and PFS, this marker may be considered to build prognostic scores for risk-adapted therapeutic strategies in APL.
Long-term effects of sustained regular medication in hypertensive patients: a cohort study in China
Authors: MA Min , Wang Huadan , Pang Linhong , Guo Zihong , Sun Manli , Zhao Yajing , Shi Yi , Wu Xia , Song Junjie , Zhu Qiuyan , Duo Lin , Wang Zhongjie , Xia Yu , Tang Mingjing , He Liping 
Published: August 2023

Abstract
Background The relationship between different grades of compliance to antihypertensive medication and blood pressure(BP) control rate remains unclear. The study underscores the relationship that long-term compliance with regular antihypertensive medication to improve rates of BP control.Methods Using 5-year follow-up data, hypertensive patients were categorized into "poor", "intermittent", and " sustained" groups according to tertiles of antihypertensive medication compliance, and the BP control rates of the three groups were compared.Then, the robust variance Poisson regression model estimated the association between three groups and the number of referrals. Kaplan-Meier calculated the cumulative risk of onset and survival probability of cardiovascular events from three medication compliance groups.Results A total of 1254 patients were enrolled and annual follow-up studies of 992, 1218, 1121, 1066 and 999 hypertensive patients were conducted from 2018 to 2022. From baseline to last follow-up, systolic BP declined from 154.69 ± 20.90 mmHg to 137.48 ± 12.44 mmHg and diastolic BP from 84.08 ± 12.80 mmHg to 79.50 ± 7.88 mmHg (p < 0.01). All three groups showed a significant improvement in BP control rates after management, especially the persistence group which reached 70% in 2022(p < 0.01). The number of referrals from the poor group was 11.5% higher than the sustained group (IRR = 1.115,95% CI:1.043 to1.193). The survival probability in the sustained group was the highest and kept at 0.950 at the end of 5 years.Conclusions Long-term high-grade compliance with antihypertensive medications significantly improves BP control rates and reduces the risk of cardiovascular disease (CVD) events and death.
Assessing Social Media Usage in Public Participation for Rapid Bus Transit Project Using Machine Learning
Authors: Yasin Eman 
Published: August 2023

Abstract
This paper aims to perform assessment of socialMedia usage, particularly Twitter, in public participation (PP) forInfrastructure projects in developing countries. The case of BusRapid Transit (BRT) of Jordan has been chosen as a case study.A comprehensive literature review was accomplished, followedby scraping the Arabic tweets relevant to the project. The tweetswere divided into three main periods, according to logical rea-soning as described in the paper. Tweets were then prepossessedincluding cleaning, tokenization, vectorization using AraBert toensure the highest contextualization for machine learning. Thefollowing analyses were performed: tweeting intensity, sentimentanalysis, tweets fluency and topic modeling. Findings of thisstudy reveals many difficulties associated with the public par-ticipation in the BRT project. The results indicated that lackof trust, appropriate communication and transparency createdlarge gap between the public and the project directors. Thisgap led to inappropriate public participation in the project, andconsequently high resistance as observed by the author. Findingsof the paper provide valuable insights for project managersand decision-makers. Understanding the public participationdimensions, the consequences of social media usage may improvepublic engagement and support the success of infrastructureprojects in developing countries like Jordan.
Cold-inducible RNA-binding protein induces inflammatory responses via NF-κB signaling pathway in normal human bronchial epithelial cells infected with streptococcus pneumoniae
Authors: Zhang Rong , Fang Kun , Mu Chunyan , Li Fujun , Zhang Liang 
Published: August 2023

Abstract
Background
Community-acquired pneumonia is a significant cause of morbidity and mortality worldwide, with substantial clinical implications that warrant further investigation and intervention. The invasion of Streptococcus pneumoniae (S. pneumoniae, S.p) can result in serious conditions such as meningitis, sepsis or pneumonia. Extracellular Cold-inducible RNA-binding protein (eCIRP) acts as a damage-associated molecular pattern that triggers inflammatory responses and plays an important role in both acute and chronic inflammatory diseases. It remains unclear whether CIRP is involved in the process of S. pneumoniae infection in normal human bronchial epithelial cells (BEAS-2B).
Methods
Cell counting kit (CCK)-8 assay was used to detect the activity of BEAS-2B cells after Streptococcus pneumoniae infection. The distribution of CIRP in BEAS-2B cells was detected by immunofluorescence. Quantitative real-time PCR (PCR) and Western Blot (WB) were used to detect the expression of CIRP, nuclear factor kappa-B (NF-κB) p65, toll like receptor-4 (TLR4), interleukin-6 (IL-6), etc. The expressions of CIRP, IL-1β, IL-6, tumor necrosis factor-α (TNF-α) and monocyte chemoattractant protein-1 (MCP-1) were assessed by enzyme linked immunosorbent assay (ELISA).
Results
We discovered that CIRP affected the activity of BEAS-2B cells that were induced by S. pneumoniae infection. After S. pneumoniae infection, CIRP transferred from the nucleus to the cytoplasm, and pro-inflammatory cytokines (IL-1, IL-6, TNF-α and MCP-1) were then produced. We further found that a significant increase in the expression of NF-κB p65 protein following S. pneumoniae infection of BEAS-2B cells, which was significantly reduced upon si-CIRP interference. Treatment with TLR4 neutralizing antibodies and an NF-κB inhibitor resulted in a significant decrease in the expressions of IL-1β, IL-6, TNF-α and MCP-1 in BEAS-2B cells.
Conclusions
Infection with S. pneumoniae induces an upregulation of CIRP expression and translocation from the nucleus to the cytoplasm in BEAS-2B cells, which subsequently leads to the release of proinflammatory factors via activation of NF-κB signaling pathway. The identification of CIRP as a key mediator in S. pneumoniae-induced inflammation provides potential targets for therapeutic intervention against community-acquired pneumonia.