bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bicontinuous oxide heteroepitaxy with enhanced photoconductivity
Authors: Shao Pao-Wen , Wu Yi-Xian , Chen Wei-Han , Zhang Mojue , Dai Minyi , Kuo Yen-Chien , Hsieh Shang-Hsien , Tang Yi-Cheng , Liu Po-Liang , Yu Pu , Chen Yuang , Huang Rong , Chen Chia-Hao , Hsu Ju-Hung , Chen Yi-Chun , Hu Jia-Mian , Chu Ying-Hao 
Published: January 2023

AbstractSelf-assembled systems have recently attracted extensive attention because they can display a wide range of phase morphologies in nanocomposites, providing a new arena to explore novel phenomena. Among these morphologies, a bicontinuous structure is highly desirable based on its high interface-to-volume ratio and 3D interconnectivity. A bicontinuous nickel oxide (NiO) and tin dioxide (SnO2) heteroepitaxial nanocomposite is revealed here. By controlling their concentration, we fabricated tuneable self-assembled nanostructures from pillars to bicontinuous structures, as evidenced by TEM-energy-dispersive X-ray spectroscopy with a tortuous compositional distribution. The experimentally observed growth modes are consistent with predictions by first-principles calculations. Phase-field simulations are performed to understand 3D microstructure formation and extract key thermodynamic parameters for predicting microstructure morphologies in SnO2:NiO nanocomposites of other concentrations. Furthermore, we demonstrate significantly enhanced photovoltaic properties in a bicontinuous SnO2:NiO nanocomposite macroscopically and microscopically. This research shows a pathway to developing innovative solar cell and photodetector devices based on self-assembled oxides.
Computational design for 4D printing of topology optimized multi-material active composites
Authors: Athinarayanarao Darshan , Prod’hon Romaric , Chamoret Dominique , Qi H. Jerry , Bodaghi Mahdi , André Jean-Claude , Demoly Frédéric 
Published: January 2023

AbstractRecent efforts on design for four-dimensional (4D) printing have considered the spatial arrangement of smart materials and energy stimuli. The development of multifunctional structures and their desired mechanical/actuation performances require tackling 4D printing from a multi-material design perspective. With the materials distributions there is an opportunity to increase the spectrum of design concepts with computational approaches. The main goal being to achieve the “best” distribution of material properties in a voxelized structure, a computational framework that consists of a finite element analysis-based evolutionary algorithm is presented. It fuses the advantages of optimizing both the materials distribution and material layout within a design space via topology optimization to solve the inverse design problem of finding an optimal design to achieve a target shape change by integrating void voxels. The results demonstrate the efficacy of the proposed method in providing a highly capable tool for the design of 4D-printed active composites.
Image dataset for benchmarking automated fish detection and classification algorithms
Authors: Francescangeli Marco , Marini Simone , Martínez Enoc , Del Río Joaquín , Toma Daniel M. , Nogueras Marc , Aguzzi Jacopo 
Published: January 2023

AbstractMultiparametric video-cabled marine observatories are becoming strategic to monitor remotely and in real-time the marine ecosystem. Those platforms can achieve continuous, high-frequency and long-lasting image data sets that require automation in order to extract biological time series. The OBSEA, located at 4 km from Vilanova i la Geltrú at 20 m depth, was used to produce coastal fish time series continuously over the 24-h during 2013–2014. The image content of the photos was extracted via tagging, resulting in 69917 fish tags of 30 taxa identified. We also provided a meteorological and oceanographic dataset filtered by a quality control procedure to define real-world conditions affecting image quality. The tagged fish dataset can be of great importance to develop Artificial Intelligence routines for the automated identification and classification of fishes in extensive time-lapse image sets.
Incidence and risk of pancreatic cancer in patients with chronic pancreatitis: defining the optimal subgroup for surveillance
Authors: Kim Hyo Suk , Gweon Tae-Geun , Park Sang Hi , Kim Tae Ho , Kim Chang Whan , Chang Jae Hyuck 
Published: January 2023

AbstractWe aimed to present the incidence and risk factors for pancreatic cancer in a multicenter retrospective cohort of patients with chronic pancreatitis (CP). Patients with ICD-10 codes for CP (K86.0, K86.1) who underwent abdominal CT or MRI between January 2010 and December 2021 in seven academic hospitals were analyzed. After exclusions, we identified 727 patients with definite CP with a median follow-up of 3.6 years (range 1.0‒12.9). During 3290 person-years of observation, pancreatic cancers were diagnosed in 16 patients (2.20%, 0.49% per year) after a median follow-up of 2.4 years (range 1.4‒6.6), with an age- and sex-standardized incidence ratio of 18.1 (95% CI 10.4‒29.5). The underlying CPs in the 16 pancreatic cancers were classified as chronic obstructive pancreatitis (10, 63%), chronic obstructive and calcifying pancreatitis (4, 25%), chronic calcifying pancreatitis (1, 6%), and autoimmune pancreatitis (1, 6%). Factors associated with pancreatic cancer development included age (HR 4.830, p = 0.006), parenchymal calcification (HR 0.213, p = 0.003), pancreatic duct stricture (HR 2.706, p = 0.048), and serum CA 19‒9 level (HR 3.567, p = 0.014). After adjustment, age over 60 years (HR 4.540, p = 0.009) and serum CA 19‒9 levels greater than 100 U/mL (HR 3.528, p = 0.015) were independent risk factors for pancreatic cancer.
Magnaporthe oryzae pathotype Triticum (MoT) can act as a heterologous expression system for fungal effectors with high transcript abundance in wheat
Authors: Jensen Cassandra , Saunders Diane G. O. 
Published: January 2023

AbstractPlant pathogens deliver effector proteins to reprogramme a host plants circuitry, supporting their own growth and development, whilst thwarting defence responses. A subset of these effectors are termed avirulence factors (Avr) and can be recognised by corresponding host resistance (R) proteins, creating a strong evolutionary pressure on pathogen Avr effectors that favours their modification/deletion to evade the immune response. Hence, identifying Avr effectors and tracking their allele frequencies in a population is critical for understanding the loss of host recognition. However, the current systems available to confirm Avr effector function, particularly for obligate biotrophic fungi, remain limited and challenging. Here, we explored the utility of the genetically tractable wheat blast pathogen Magnaporthe oryzae pathotype Triticum (MoT) as a suitable heterologous expression system in wheat. Using the recently confirmed wheat stem rust pathogen (Puccina graminis f. sp. tritici) avirulence effector AvrSr50 as a proof-of-concept, we found that delivery of AvrSr50 via MoT could elicit a visible Sr50-dependant cell death phenotype. However, activation of Sr50-mediated cell death correlated with a high transgene copy number and transcript abundance in MoT transformants. This illustrates that MoT can act as an effective heterologous delivery system for fungal effectors from distantly related fungal species, but only when enough transgene copies and/or transcript abundance is achieved.
Long-term taxonomic and functional stability of the gut microbiome from human fecal samples
Authors: Kim Jae Hyun , Jeon Ji-Young , Im Yong-Jin , Ha Na , Kim Jeon-Kyung , Moon Seol Ju , Kim Min-Gul 
Published: January 2023

AbstractAppropriate storage of fecal samples is a critical step for unbiased analysis in human microbiome studies. The purpose of this study was to evaluate the stability of the fecal microbial community for up to 18 months. Ten healthy volunteers provided fecal samples at the Jeonbuk National University Hospital. Stool samples were stored under the following six conditions: four different storage temperatures (− 70 °C, − 20 °C, 4 °C, and room temperature [20–25 °C]) and two different collection tubes (OMNIgene-Gut and DNA/RNA shield-fecal collection tubes). The gut microbiome was analyzed with 16S rRNA sequencing. We compared the taxonomic composition, alpha diversity, beta diversity and inferred pathway abundance between the baseline and 18 months after storage. Samples collected in the DNA/RNA Shield-fecal collection tubes showed the best performance in preservation of the taxonomic composition at 18 months. Pairwise differences in alpha diversity metrics showed the least deviation from zero. The PERMANOVA test showed non-significant change of beta diversity metrics (Unweighted Unifrac: q-value 0.268; Weighted Unifrac: q-value 0.848). The functional stability was significantly well preserved in the DNA/RNA Shield-fecal collection tubes (adjusted p value < 0.05). Our results demonstrate the use of the DNA/RNA Shield-fecal collection tube as an alternative storage method for fecal samples to preserve the taxonomic and functional stability of the microbiome over a long term.
Study of 32 new phage tail-like bacteriocins (pyocins) from a clinical collection of Pseudomonas aeruginosa and of their potential use as typing markers and antimicrobial agents
Authors: Blasco Lucía , de Aledo Manuel González , Ortiz-Cartagena Concha , Blériot Inés , Pacios Olga , López María , Fernández-García Laura , Barrio-Pujante Antonio , Hernández-Garcia Marta , Cantón Rafael , Tomás María 
Published: January 2023

AbstractPhage tail-like bacteriocins (PTLBs) are large proteomic structures similar to the tail phages. These structures function in bacterial competition by making pores in the membrane of their competitors. The PTLBs identified in Pseudomonas aeruginosa are known as R-type and F-type pyocins, which have a narrow spectrum of action. Their specificity is determined by the tail fiber and is closely related to the lipopolysaccharide type of the target competitor strain. In this study, the genome sequences of 32 clinical of P. aeruginosa clinical isolates were analysed to investigate the presence of R-type and F-type pyocins, and one was detected in all strains tested. The pyocins were classified into 4 groups on the basis of the tail fiber and also the homology, phylogeny and structure of the cluster components. A relationship was established between these groups and the sequence type and serotype of the strain of origin and finally the killing spectrum of the representative pyocins was determined showing a variable range of activity between 0 and 37.5%. The findings showed that these pyocins could potentially be used for typing of P. aeruginosa clinical isolates, on the basis of their genomic sequence and cluster structure, and also as antimicrobial agents.
A maladaptive feedback mechanism between the extracellular matrix and cytoskeleton contributes to hypertrophic cardiomyopathy pathophysiology
Authors: Viola Helena M. , Richworth Caitlyn , Solomon Tanya , Chin Ian L. , Szappanos Henrietta Cserne , Sundararaj Srinivasan , Shishmarev Dmitry , Casarotto Marco G. , Choi Yu Suk , Hool Livia C. 
Published: January 2023

AbstractHypertrophic cardiomyopathy is an inherited disorder due to mutations in contractile proteins that results in a stiff, hypercontractile myocardium. To understand the role of cardiac stiffness in disease progression, here we create an in vitro model of hypertrophic cardiomyopathy utilizing hydrogel technology. Culturing wild-type cardiac myocytes on hydrogels with a Young’s Moduli (stiffness) mimicking hypertrophic cardiomyopathy myocardium is sufficient to induce a hypermetabolic mitochondrial state versus myocytes plated on hydrogels simulating healthy myocardium. Significantly, these data mirror that of myocytes isolated from a murine model of human hypertrophic cardiomyopathy (cTnI-G203S). Conversely, cTnI-G203S myocyte mitochondrial function is completely restored when plated on hydrogels mimicking healthy myocardium. We identify a mechanosensing feedback mechanism between the extracellular matrix and cytoskeletal network that regulates mitochondrial function under healthy conditions, but participates in the progression of hypertrophic cardiomyopathy pathophysiology resulting from sarcomeric gene mutations. Importantly, we pinpoint key ‘linker’ sites in this schema that may represent potential therapeutic targets.
Analysis of lung scan imaging using deep multi‐task learning structure for Covid‐19 disease
Authors: Kordnoori Shirin , Sabeti Malihe , Mostafaei Hamidreza , Banihashemi Saeed Seyed Agha 
Published: January 2023

AbstractCovid‐19 caused by the SARS‐CoV2 virus has become a pandemic all over the world. By growing in a number of cases, there is a need for clinical decision‐making system based on machine learning models. Most of the previous studies have examined only one task, while the detection and identification of infectious area are conducted simultaneously in the real world. Thus, the present study aims to propose a multi‐task model which can perform automatic classification‐segmentation for screening Covid‐19 pneumonia by using chest CT imaging. This model includes a common encoder for feature representation, one decoder for segmentation, and a multi‐layer perceptron for classification, respectively. The proposed model can evaluate three datasets, along with the effect of images size on the output of the model. The outputs were examined in both multi‐task and single‐task learning. The result indicates that the effect of multi‐task is significant in improving the results, which can increase the outputs of each task performance to 95.40% accuracy in classification and 95.40% in segmentation. Further, the model represented the highest results among the state‐of‐the‐art methods. The proposed model can be applied as a primary screening tool to help primary service staff in better referral of the suspected patients to specialists.
Incidents et accidents liés à l’utilisation médicale des rayonnements ionisants chez les professionnels à Abidjan. À propos d’une série de 3 cas
Authors: Kouamé-Koutouan A. , Konan A.N. , Zunon-Kipré E. , Kouassi-Aboukoua N.N. , N’drin N.K.J. , Touré M. , Traoré M. 
Published: January 2023

Objectif : Analyser les évènements nucléaires survenus chez les professionnels dans les services des hôpitaux publics de référence utilisant les rayonnements ionisants (RI). Matériels et méthodes : Étude rétrospective à visée descriptive, sur une période de 11 ans allant de décembre 2010 à juillet 2020, dans les services d’imagerie médicale et de radiodiagnostic des hôpitaux publics de référence. Nous avons recensé tous les accidents et incidents nucléaires enregistrés par les services de santé au travail, décrits leurs circonstances de survenue et définit leur sévérité selon l’Échelle internationale des évènements nucléaires et radiologiques (INES). Résultats : Nous avons relevé 3 évènements nucléaires, soit un taux d’incidence annuel de 0,3 ‰. Ils étaient tous classés incidents mineurs de niveau 2 selon l’échelle INES. Il n’y a pas eu d’incident grave ni accident nucléaire. Les circonstances de survenue étaient accidentelle pour 1 cas et en rapport avec une faute professionnelle pour le deuxième. Dans le troisième cas, les circonstances n’étaient pas élucidées. Ces évènements sont survenus exclusivement chez des manipulateurs de radiologie. Aucun évènement nucléaire n’était rapporté chez les médecins radiologues et les autres professionnels travaillant à proximité des sources de RI. Une éviction définitive des postes de travail directement sous rayonnement a été prise pour un travailleur. Conclusion : Les évènements nucléaires chez les professionnels de la santé étaient rares, de faible gravité et concernaient exclusivement les manipulateurs en radiologie. Le facteur humain en était la cause.
Phosphorus supplementation improves the growth and reproductive performance of female Brahman cattle grazing phosphorus-deficient pastures in the Victoria River District, Northern Territory, Australia
Authors: Schatz T. J. , McCosker K. D. , Heeb C. 
Published: January 2023

Context There is a paucity of information on the responses to phosphorus (P) supplementation of breeder herds grazing P-deficient rangelands in northern Australia. Aims A study examined the production and economic benefits of P supplementation of Brahman females grazing P-deficient pastures in the Northern Territory (NT) of Australia. Methods Two treatment groups (initially n ~ 90) grazed two similar P-deficient paddocks for 5 years after weaning (at approximately 6 months of age). Management was the same except that the loose lick mineral supplement either contained P (+P) or did not contain P (−P). Performance attributes were measured from commencement until after the cows had the opportunity to calve during three successive annual cycles. Key results The cows in the +P treatment were overall heavier (P < 0.001), taller (P < 0.001) and had higher plasma inorganic P (PiP) concentrations (P < 0.001) than did those in the −P treatment at every measurement date after the first wet season. Pregnancy rates in lactating cows were 25%, 39% and 63% units higher (P < 0.01) in +P in 2017, 2018 and 2019 respectively and overall average weaner weight was 33 kg heavier (P < 0.001) in +P. Due to higher weaning rates and heavier weaning weights, +P produced about AU$39 365 more value of weaners per 100 heifers allocated to each treatment than did −P over the first three calf crops. The cumulative mortality rate was 12% higher in the −P over the 5 years (14.8% vs 2.2%, P < 0.01), and would have been even higher if at-risk −P cows had not been fed additional supplements. Return on investment calculations indicated that each AU$1 spent on P supplement returned AU$4.98 in value of extra calves weaned and AU$7.88 in extra total liveweight increase over the 5 years of the study. Conclusions The large production and financial benefits from P supplementation observed in this study are relevant to most northern Australian properties where soils are P deficient, although the magnitude of response is likely to vary depending on the level of P deficiency. Implications The large production and economic benefits from P supplementation in this study demonstrated the importance of P supplementation for breeder herds grazing P-deficient pastures.
The Maresin 1–LGR6 axis decreases respiratory syncytial virus-induced lung inflammation
Authors: Krishnamoorthy Nandini , Walker Katherine H. , Brüggemann Thayse R. , Tavares Luciana P. , Smith Ethan W. , Nijmeh Julie , Bai Yan , Ai Xingbin , Cagnina R. Elaine , Duvall Melody G. , Lehoczky Jessica A. , Levy Bruce D. 
Published: January 2023

The resolution of infection is an active process with specific molecular and cellular mechanisms that temper inflammation and enhance pathogen clearance. Here, the specialized pro-resolving mediator (SPM) Maresin 1 (MaR1) inhibited respiratory syncytial virus (RSV)-induced inflammation. inlerleukin-13 production from type 2 innate lymphoid cells (ILC) and CD4 T helper type 2 cells was decreased by exogenous MaR1. In addition, MaR1 increased amphiregulin production and decreased RSV viral transcripts to promote resolution. MaR1 also promoted interferon-β production in mouse lung tissues and also in pediatric lung slices. MaR1 significantly inhibited the RSV-triggered aberrant inflammatory phenotype in FoxP3-expressing Tregs. The receptor for MaR1, leucine-rich repeat-containing G protein-coupled receptor 6 (LGR6), was constitutively expressed on Tregs. Following RSV infection, mice lacking Lgr6 had exacerbated type 2 immune responses with an increased viral burden and blunted responses to MaR1. Together, these findings have uncovered a multi-pronged protective signaling axis for MaR1–Lgr6, improving Tregs’s suppressive function and upregulating host antiviral genes resulting in decreased viral burden and pathogen-mediated inflammation, ultimately promoting restoration of airway mucosal homeostasis.
The facilitative use of learner-initiated translanguaging in Japanese EFL contexts
Authors: Harumi Seiko 
Published: January 2023

Abstract
This study explores the facilitative use of learner-initiated translanguaging and teacher responsiveness
to its use in 68 dyads of conversational interaction between a teacher and individual students in tertiary Japanese EFL
contexts. Adopting conversation analysis as an analytical framework, it aims to extend our understanding of the use of
learner-initiated translanguaging and teacher responsiveness to translanguaging as an important interactional resource
for learners to achieve interactional goals. The study identifies eight facilitative uses of L1. On the one hand, these
uses contribute to the progressivity of talk as self-addressed translanguaging. On the other, they
support intersubjectivity as co-constructed translanguaging in L2 interaction. These uses include (1)
connectives for topic management; (2) floor-holding devices; (3) explicit word searches; (4) lexical gap fillers; (5)
understanding displays; (6) clarification requests; (7) confirmation checks; and (8) explicit request for assistance.
The study also reveals that learners’ self-initiated repair using L1 was frequently observed and that its use was
intertwined with translanguaging in its functionality in discourse for meaning-making as a discursive practice. This
study suggests that the use of translanguaging in the L2 classroom can be an indispensable tool to optimise learners’
classroom interactional competence.
Identifying glitches near gravitational-wave signals from compact binary coalescences using the Q-transform
Authors: Vazsonyi Leah , Davis Derek 
Published: January 2023

Abstract
We present a computational method to identify glitches in gravitational-wave data that occur nearby gravitational-wave signals from compact binary coalescences. The Q-transform, an established tool in LIGO-Virgo-KAGRA data analysis, computes the probability of any excess in the data surrounding a signal against the assumption of a Gaussian noise background, flagging any significant glitches. Subsequently, we perform validation tests on this computational method to ensure self-consistency in colored Gaussian noise, as well as data that contains a gravitational-wave event after subtracting the signal using the best-fit template. Finally, a comparison of our glitch identification results from real events in LIGO-Virgo’s third observing run against the list of events which required glitch mitigation shows that this tool will be useful in providing precise information about data quality to improve astrophysical analyses of these events.
Emergence of Wigner oscillations in a model of real time cooling process: a time-dependent density-functional theory approach
Authors: Vieira Daniel 
Published: January 2023

Abstract
Friedel and Wigner oscillations are well known phenomena occurring in quantum systems. Specifically, in a system composed by N confined fermions, the former are characterized by the presence of

N

/

2

peaks in the density distributions, whereas the last by N peaks. Here, we consider N = 2 fermions harmonically confined in one-dimensional quantum dots. It is known that the transition from the Friedel to the Wigner oscillations is induced by the increment of interaction between the fermions. The increment of temperature, on the other hand, acts on eliminating the oscillations. In this context, by employing a time-dependent density-functional theory formalism, we here obtain the emergence of Wigner oscillations in a model which simulates a real time cooling process.