bluuebunny/crossref_metadata_2025_split huggingface dataset:
Global research trends of the studies on Murraya koenigii (L.) spreng: a Scopus-based comprehensive bibliometric investigation (1965–2023)
Authors: Abdelwahab Siddig Ibrahim , Taha Manal Mohamed Elhassan 
Published: September 2023

Abstract
Background
Murraya koenigii (L.) Spreng. has several well-established nutritional and therapeutic applications. Following our desire to investigate the global and scientific community's knowledge of medicinal plants, this study was intended to examine the evolution of knowledge related to M. Koenigii studies. The primary purpose of this paper is to clarify the status of these studies, investigate their methods, findings, and trends, and define their significance within the current research landscape.

Results
To achieve these goals, bibliometric analysis was conducted, retrieving, and analyzing 934 original articles published between 1965 and 2023 based on Scopus Dataset results. Data were exported as CVS (comma-separated values) and BibTex files and analyzed using Bibliometrix and VOSviewer software. Articles from 502 sources have been identified, averaging 21.8 citations per document. The research in this plant has had exponential growth (R2 = 0.77). International co-authorship is 13.08%. India and Malaysia are the top publishing countries. Debajo, A.C. (Nigeria), Phatak,R.S. (India), and Sukari,M.A. (Malaysia) are the most productive authors. The top source is the Journal of Ethnopharmacology. "Green synthesis," "nanoparticles," "oxidative stress," "Asian citrus psyllid," "apoptosis," "antimicrobial," "anticancer," "Chromatographic profile," "bioactive compounds," and "alkaloids" are strongly related to the current trends in M. Koenigii research. Regarding the specialized topics, M. Koenigii's study concentrated on using this plant as an antioxidant agent in manufacturing and biological systems. Dynamic subjects like chromatographic profiles, essential oils, and Asian citrus psyllids were included in the motor theme.

Conclusions
The current study used bibliometric techniques to evaluate research on M. Koenigii and identify trends and potential future research hot spots.
A rare cause of neonatal feeding intolerance: congenital segmental intestinal dilatation—a case report
Authors: Tan Hooi Hooi , Tan Shung Ken , Bt Abd. Halim Roslina , Md Yusof Md Yusri , Puspanathan Pavitratha , Teoh Pak Inn 
Published: September 2023

Abstract
Background
Congenital segmental intestinal dilatation (CSID) is a rare cause of neonatal bowel obstruction. Patients can present in the early newborn period with feeding intolerance and abdominal distension. Diagnosis is challenging due to its rarity and non-specific clinical and radiological findings in a well neonate. Surgical excision remains the mainstay treatment for this disease.

Case presentation
We report a case of a newborn male with congenital segmental ileal dilatation, who presented with abdominal distension and feeding intolerance. He was born preterm at 32 weeks and was treated for presumed sepsis due to a premature rupture of the membrane. The patient developed persistent abdominal distension upon initiation of feedings with large amount of gastric aspirates. Otherwise, there was no delay in the passage of meconium. Serial abdominal radiographs showed persistent focal bowel dilatation on the right side. He was initially diagnosed with small bowel atresia. Ultrasound abdomen and lower gastrointestinal contrasted study showed focal ileal dilatation with no evidence of pneumoperitoneum. Intraoperative findings revealed a segmental ileal dilatation with no evidence of mechanical obstruction. The abnormal dilated bowel was excised and sent for histopathological examination. He recovered well after surgery.

Conclusion
Diagnosis of CSID can be challenging due to its clinical polymorphism and non-specific radiological findings. CSID should be suspected in neonates with feeding intolerance and focal intestinal dilatation without clinical features of sepsis, peritonitis, or mechanical obstruction. Surgical excision is curative with a good outcome.
Quantification of pulmonary opacities using artificial intelligence in chest CT scans during SARS-CoV-2 pandemic: validation and prognostic assessment
Authors: Montoro Fernando Sánchez , Gordo María Luz Parra , Tascón Áurea Díez , de Gracia Milagros Martí , Velez Silvia Ossaba , Fernández Susana Fernández , Vallano Rebeca Gil , Acosta Velásquez Kevin Stephen 
Published: September 2023

Abstract
Purpose
To assess whether the analysis of pulmonary opacities on chest CT scans by AI-RAD Companion, an artificial intelligence (AI) software, has any prognostic value.

Background
In December 2019, a new coronavirus named SARS-CoV-2 emerged in Wuhan, China, causing a global pandemic known as COVID-19. The disease initially presents with flu-like symptoms but can progress to severe respiratory distress, organ failure, and high mortality rates. The overwhelming influx of patients strained Emergency Rooms worldwide. To assist in diagnosing and categorizing pneumonia, AI algorithms using deep learning and convolutional neural networks were introduced. However, there is limited research on how applicable these algorithms are in the Emergency Room setting, and their practicality remains uncertain due to most studies focusing on COVID-19-positive patients only.

Methods
Our study has an observational, analytical, and longitudinal design. The sample consisted of patients who visited our emergency room from August 5, 2021, to September 9, 2021, were suspected of having COVID-19 pneumonia, and underwent a chest CT scan. They were categorized into COVID-19 negative and positive groups based on PCR confirmation. Lung opacities were evaluated separately by a team of radiologists and a commercial AI software called AI-Rad Companion (by Siemens Healthineers). After 5 months we gathered clinical data, such as hospital admission, intensive care unit (ICU) admission, death, and hospital stay.

Results
The final sample included 304 patients (144 females, 160 males) with a mean age of 68 ± 19 std. Among them, 129 tested negative for COVID-19 and 175 tested positive. We used AI-generated opacity quantification, compared to radiologists' reports, to create receiver operating characteristic curves. The area under the curve ranged from 0.8 to 0.9 with a 95% confidence interval. We then adjusted opacity tests to a sensitivity cut-off of 95%. We found a significant association between these opacity tests and hospital admission and ICU admission (Chi-Squared, P < 0.05), as well as between the percentage of lung opacities and length of hospital stay (Spearman's rho 0.53–0.54, P < 0.05) in both groups.

Conclusions
During the SARS-CoV-2 pandemic, AI-based opacity tests demonstrated an association with certain prognostic markers in patients with suspected COVID-19 pneumonia, regardless of whether a PCR-confirmed coronavirus infection was ultimately detected.
hMSCs treatment attenuates murine herpesvirus-68 (MHV-68) pneumonia through altering innate immune response via ROS/NLRP3 signaling pathway
Authors: Qin Aiping , Wang Xiao-juan , Fu Jijun , Shen Ao , Huang Xiaotao , Chen Zhida , Wu Huiting , Jiang Yu , Wang Qian , Chen Fei , Xiang Andy Peng , Yu Xiyong 
Published: September 2023

AbstractImmunocompromised individuals are particularly vulnerable to viral infections and reactivation, especially endogenous herpes viruses such as Epstein-Barr virus (EBV), a member of oncogenic gamma-herpesviruses, which are commonly linked to pneumonia and consequently significant morbidity and mortality. In the study of human and animal oncogenic gammaherpesviruses, the murine gamma-herpesviruses-68 (MHV-68) model has been applied, as it can induce pneumonia in immunocompromised mice. Mesenchymal stem cell (MSC) treatment has demonstrated therapeutic potential for pneumonia, as well as other forms of acute lung injury, in preclinical models. In this study, we aim to investigate the therapeutic efficacy and underlying mechanisms of human bone marrow-derived MSC (hMSC) on MHV-68-induced pneumonia. We found that intravenous administration of hMSCs significantly reduced lung damages, diminished inflammatory mediators and somehow inhibited MHV-68 replication. Furthermore, hMSCs treatment can regulate innate immune response and induce macrophage polarization from M1 to M2 phenotype, could significantly alter leukocyte infiltration and reduce pulmonary fibrosis. Our findings with co-culture system indicated that hMSCs effectively reduced the secretion of of inflammation-related factors and induced a shift in macrophage polarization, consistent with in vivo results. Further investigations revealed that hMSCs treatment suppressed the activation of macrophage ROS/NLRP3 signaling pathway in vivo and in vitro. Moreover, administration of MCC950, a selective NLRP3 inhibitor has been shown to effectively reduce ROS production and subsequently alleviate inflammation induced by MHV-68. Taken together, our work has shown that hMSCs can effectively protect mice from lethal MHV-68 pneumonia, which may throw new light on strategy for combating human EBV-associated pneumonia.
Controlling Excited-State Dynamics and Chemical Reactivities of Platinum Acetylide Complexes via Self-Threading Ligands with Permethylated α-Cyclodextrin
Authors: Masai Hiroshi 
Published: September 2023

Abstract
Exterting control over the excited-state dynamics and chemical reactivities of transition metal complexes allows an enhancement in their physical properties and the development of their applications to novel materials. Hence, in this study, transition metal complexes were incorporated into a protective environment using permethylated α-cyclodextrin (PM α-CD)-based macrocycles. As a novel design concept for protective ligands in transition metal complexes, the macrocyclic PM α-CDs were efficiently introduced and fixed close to the metal centers via covalent bonding with the self-threading structures of rigid π-conjugated ligands. The protection of the transition metal complexes prevented undesired conformational changes and chemical reactions, thereby enhancing their functional properties and revealing the potential reactivities of the transition metals. In this account, the unique chemical reactivities and optical properties of transition metal complexes protected with PM α-CDs are summarized, with a focus on the distinctive features of platinum acetylide complexes and their applications to polymer materials.
Structure Identification of Dynamic Zinc(II)-ligand Assemblies in Solution Based on Ligand Chirality
Authors: Ogata Daiji , Yuasa Junpei 
Published: September 2023

Abstract
This study demonstrates that pendant chirality on building ligands functions as a valuable indicator for identifying metal-ligand dynamic assemblies in solution: Racemic ligands (L(R) and L(S)) with zinc ions (Zn2+) give (Zn2+)2(L(R))n(L(S))(4−n) (n = 0–4) assemblies with statistical L(R) and L(S) positioning, which can be analyzed by 1H NMR spectroscopy with a statistical model.
Post-graduate educational environment of two parallel programs in Pediatric Medicine
Authors: Hamid Muhmmad Haroon , Mahboob Usman , Khan Rehan Ahmed 
Published: September 2023

Objective: To compare the trainees’ perception of the Educational Environment (EE) of the two parallel post-graduate training programs (MD & FCPS) in Pediatric Medicine.
Methods: This quantitative cross-sectional study was carried out by Department of Medical Education UOL and Department of Pediatric Medicine KEMU from February to December 2021. Data about the perception of EE was collected from the Pediatric Medicine trainees by purposive sampling using the 40 items PHEEM inventory. The inventory has three perception domains: role autonomy, teaching, and social support. In addition, to mean scores, the inventory also gives interpretation according to the score ranges. The FCPS and MD trainees of both genders and all years of training across the institutions of Punjab were approached using Google Forms. SPSS (v 23.0) was used for descriptive and analytic statistics.
Results: A total of 327 trainees’ responses were included-188 (57.5%) FCPS and 139 (42.5%) MD trainees. The mean overall score was 92±19.7 for FCSP and 93.88±21.5 for MD trainees (p-value 0.41). The interpretation of the overall score was “more positive than negative but room for improvement” in 67.3%. For the subscales of role autonomy, teaching, and social support, the perception was positive by 71%, 80%, and 45% of trainees, respectively. Except for three individual items, the mean scores of the subscales and the individual items were not statistically different between the two groups.
Conclusion: The Pediatric Medicine trainees’ perception of the educational environment in the FCPS and MD groups was comparable overall and in all three domains. Individual item analysis showed almost similar areas for improvement in both programs.
doi: https://doi.org/10.12669/pjms.39.6.7696
How to cite this: Hamid MH, Mahboob U, Khan RA. Post-graduate educational environment of two parallel programs in Pediatric Medicine. Pak J Med Sci. 2023;39(6):---------. doi: https://doi.org/10.12669/pjms.39.6.7696
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Perceptions about the Implementation and Education of Telemedicine among University Students in Riyadh, Saudi Arabia
Authors: Arain Shoukat  Ali , Al Ajlan Juman Saleh , Ahmed Mohammed Ejaz , Alshehry Amjad Abdullah , Meo Sultan Ayoub 
Published: September 2023

Objectives: This study evaluated and compared the perceptions, awareness, and experiences of telemedicine among university students in Riyadh.
Methods: In this cross-sectional study, a questionnaire was distributed electronically to undergraduate university students in Riyadh. The study was conducted from September 2021 to March 2022. Five-point Likert scale data were reported as percent agreement, while open-text comments were reported as recurring themes. Besides, the perceptions of medical students were compared with students from other disciplines.
Results: Of 564 participants, 209 (37%) were medical students. Most respondents agreed that telemedicine could save patients’ time (77.7%) and improve access to healthcare (73.4%). The agreement was low for the statements that doctors would effectively evaluate the clinical features (39.2%) and that patients would effectively communicate their illnesses (44.3%). The agreement of medical students compared to students from other disciplines was even lower for these statements (25% vs. 47%; p<0.001) and (37% vs. 48%; p=0.03), respectively. Most medical students reported that they never learned about telemedicine (65%) and its tools (69%). Lack of awareness, training of healthcare workers and perceived lower quality of healthcare emerged as the most relevant factors for the limited acceptance of telemedicine.
Conclusions: Most participants perceived that telemedicine could save patients’ time and improve access to healthcare. The low agreement, especially of medical students, for the ability of physicians to evaluate clinical features and of patients to communicate illnesses effectively possibly represented suboptimal education of telemedicine in medical curricula. Thus, incorporating telemedicine into medical curricula and improving public awareness might expedite telemedicine implementation.
doi: https://doi.org/10.12669/pjms.39.6.7797
How to cite this: Arain SA, Al Ajlan JS, Ahmed ME, Alshehry AA, Meo SA. Perceptions about the Implementation and Education of Telemedicine among University Students in Riyadh, Saudi Arabia. Pak J Med Sci. 2023;39(6):---------. doi: https://doi.org/10.12669/pjms.39.6.7797
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Stakeholders’ perspectives and experiences of patient and public involvement (PPI) in clinical trials in maternal and neonatal healthcare: protocol for a qualitative evidence synthesis
Authors: Hannon Kathleen , Eustace-Cook Jessica , Daly Déirdre , Smith Valerie 
Published: September 2023

Background: Patient and public involvement (PPI) has the potential to improve the relevance of trial outcomes and improve participant recruitment within clinical trials. However, the literature on PPI approaches, outcomes, and attitudes towards PPI in specific clinical research areas is limited. We are interested to know the current approaches to and views of PPI within maternal and neonatal clinical trials, from the perspective and experience of involved stakeholders. Methods: A qualitative evidence synthesis (QES) of stakeholders’ perspectives and experiences of PPI will be conducted. Stakeholders will include any individual involved in maternal or neonatal clinical trials with experience of PPI in the area or who expresses their views on PPI. The electronic bibliographic databases CINAHL, MEDLINE, PsycINFO, EMBASE, Web of Science and the Maternity and Infant Care (OVID) will be searched from inception. Qualitative studies, mixed-methods studies where the qualitative data can be extracted independently, and surveys with open-ended qualitative questions, will be included. Aims: The QES seeks to explore stakeholders’, including PPI contributors, trial participants and guardians, and trial researchers, perspectives and experiences of PPI in maternal and neonatal clinical trials. Discussion: THE QES will provide an understanding of how PPI is understood, operationalised and experienced by stakeholders in maternal and neonatal clinical trials, with the aim of identifying good practice and areas for improvement. PROSPERO registration: CRD42023383878 (2nd March 2023)
The impact of COVID-19 on the care of diabetic foot ulcers: a scoping review protocol
Authors: Flynn Sinead , Kirwan Ellen , MacGilchrist Claire , McIntosh Caroline 
Published: September 2023

Background: The Coronavirus disease 2019 (COVID-19) pandemic had a significant and on-going impact on the delivery of health and social care services across the globe due to imposed restrictions required to control the spread of the virus. This, undoubtedly, impacted population health through disruption to healthcare services and delayed delivery of care. The impact of these restrictions and precautions were especially pertinent to those who were deemed at high risk of developing complications from COVID-19, for example, those living with chronic disease and significant comorbidities including diabetes mellitus (DM) and diabetic foot ulceration (DFU). Objectives: The objectives of this scoping review are to conduct a systematic search of the literature to identify the nature and extent of the research evidence to which the COVID-19 pandemic impacted and disrupted the care of DFU and the subsequent impact on patient outcomes. Secondly, to identify transformation in models of care and service delivery, adoption of new technologies and new models of service innovations including modalities such as telehealth that were adopted during the pandemic. Methods: This systematic scoping review will be conducted in accordance with the Joanna Briggs Institute methodology for scoping reviews and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping reviews (PRISMA-ScR). Discussion: It is well established that DFU are a devastating complication of DM that cause significant morbidity and mortality, however, there is a need to establish the impact of the COVID-19 pandemic on those living with DFU during the pandemic. We will synthesise and appraise the current literature to provide an in depth understanding of the impact of COVID-19 and the global response on the care of DFU including radical transformation in models of care and service delivery, adoption of new technologies and new models of service innovations, including modalities such as telehealth.
Building Ambition
Authors: Stone Tom 
Published: September 2023

IN AN EXCLUSIVE INTERVIEW, SUNGWOO LEE – HYUNDAI CONSTRUCTION EQUIPMENT EUROPE’S MANAGING DIRECTOR AND A RISING STAR AT THE OEM – GIVES INSIGHT INTO EVERYTHING FROM THE 2021 ACQUISITION OF DOOSAN INFRACORE AND MARQUE-SWAPPING, TO AI SAFETY SYSTEMS, ELECTRIFICATION AND HYDROGEN FUEL CELLS
MENÂKIBNÂMELERDE YASAK MOTİFİ
Authors: AKÇAM Harun 
Published: September 2023

Halk anlatıları, barındırdıkları motifler ile metinler arasında kültürel bir ilişki kurmaktadır. Motifler, birer kültür taşıyıcısı olarak farklı dönemler ve farklı anlatıların içinde de bulunmaktadır. Böylece halk anlatılarının kültür coğrafyası içinde birbirlerine olan benzerlik ve farklılıkları tespit edilebilmektedir. Bu tespitlerden hareketle de akademik düzeyde çalışmalar yapılmaktadır.
Menâkıbnâmeler, Tasavvufî Halk Edebiyatında çoğunlukla nesir anlatılar olarak hikâye etmenin önemli eserleri arasındadır. Menâkıbnâmeler yalnızca bir ya da birden fazla keramet sahibi din büyüklerinin hayatlarını anlatmak amacıyla yazılmazlar. Aynı zamanda menâkıbnâmeler, bağlı bulunulan dinî zümrelerin kültürlerini hem daha geniş alanlara yaymak hem de daha sonraki kuşaklara aktarmak amacını da taşırlar. Böylece bu dinî zümrelerin bilinirlik ve kalıcılıkları sağlanmış olur.
Çalışmada menâkıbnâmelerde görülen motiflerden yasak motifi üzerinde durulmuş ve Stith Thompson’un motif indeksinde bulunan bu motif incelenmeye tabi tutulmuştur. Hacı Bektaş Veli, Abdal Musa, Kaygusuz Abdal ve Seyyid Ali Sultan menâkıbnâmeleri çalışmada incelenmiştir. Bu incelemeden hareketle menâkıbnâmelerin işlevlerinin motifler üzerinden nasıl kurulduğu ve dinleyici veya takipçilere bu yolla nasıl aktarılmış olduğu tespit edilmeye çalışılmıştır.
Behavioral change readiness among obese adolescents in Jakarta, Indonesia
Authors: Friska Dewi , Kekalih Aria , Harimurti Muhammad Erlangga Putra , Nabila Deviena 
Published: September 2023

BACKGROUND Prochaska’s transtheoretical model of behavioral change process, consisting of stages and processes of change, should be monitored to evaluate obesity management, particularly in adolescents. Two of four processes of change are supporting relationships, which promote behavioral change, and weight management actions, which are activities that push individuals to a particular direction in patients’ weight loss progress. This study aimed to determine the participants’ current stages of change, nutritional status, and their relationship with the processes of change.
METHODS This cross-sectional study used secondary data collected in 2018 from 115 obese adolescents aged 15–21 years in Jakarta, Indonesia, using an Indonesian-translated and validated questionnaire adapted from Andrés et al’s study. The questionnaire evaluated participants’ processes of change, focusing on scores of supporting relationships (5 items) and weight management actions (10 items).
RESULTS Of the participants, 71.3% were classified as obese grade I, and 28.7% were obese grade II. Most participants were in the contemplation (31.3%) and action (31.3%) stages. The mean supporting relationships and weight management actions scores were different between participants with obese I and obese II (66.67 versus 80, p = 0.004; 64.17 versus 70, p = 0.008, respectively). Meanwhile, no differences were identified in supporting relationships and weight management actions scores in all stages of change.
CONCLUSIONS Adolescents with obesity and higher BMI (based on the obesity grading of the WHO Asia Pacific) tended to have significantly higher scores for supporting relationships and weight management actions, indicating that external reinforcement and immediate weight loss actions played pivotal roles in readiness for behavioral change.