bluuebunny/crossref_metadata_2025_split huggingface dataset:
COVID-19 Vaccine Coverage and Hesitancy in Long-Term Care Facilities, Houston, Texas
Authors: Oladimeji Abisola , Afe Abayomi , Olumuyiwa Tolulope , Evans Offiong Charlene , Chaudhary Ifrah , Turibekov Bakbergen , Aikulola Oluwayemisi , Persse Courtney , Deadmon Jahana , Hansen Kristine , Vijayan Vijisha , Mora Wanda , Farris Jacob , Dean Krysta , Short Kristine 
Published: July 2023

Background
Vaccine hesitancy threatens a reversal of progress made in tackling vaccine-preventable diseases. The Houston, Texas, Health Department assessed COVID-19 vaccine availability and uptake in these facilities after the emergency use authorization of the COVID-19 vaccines in United States.
Population and Methods
A facility-based cross-sectional study was conducted using a structured interviewer-administered questionnaire to elicit data on facility demographics, vaccine availability, residents and staff vaccine uptake at time of assessment. The unit of inquiry was the facility. We calculated frequencies and assessed association with facility type. Facilities were classified as: small-scale facilities (SSF) ≤ 10 beds, medium scale (MSF) 11-50 beds, and large-scale (LSF) > 50 beds.
Results
A total of 118 facilities were enrolled, with 2,431 residents and 2,290 staff. Twenty-five (14.5%) of the facilities were LSF, 47 (39.8%) MSF, and 46 (39.0%) SSF. Overall, 70 (59.3%) facilities had COVID-19 vaccine available. The staff of these facilities were four-times as likely as the patients to be unvaccinated (prevalence ratio= 4.1; 95% CI= 3.7, 4.6) since the vast majority of residents, (86.5%), were vaccinated but less than half of staff (44.2%) were (P < 0.0001). Reasons provided for vaccine hesitancy included fear of side effects from a new vaccine, need to wait and see what happens to others, government distrust, religious beliefs, conspiracy theories among other things.
Discussion
The findings supported highlighted a preventable gap in the protection of the elderly in these facilities and prompted a health education campaign tackling vaccine hesitancy and encourage vaccine uptake.
Effect of Mouthwash in Reducing the Oral Load of SARS-CoV-2
Authors: Balafif Felisha Febriane , Rafisa Anggun , Kuswandani Faisal , Najmi Nuroh 
Published: July 2023

The use of mouthwash as an oral antimicrobial agent against SARS‐CoV‐2 infection. It is important to investigate the efficacy of mouthwash solutions against salivary SARS-CoV-2 in order to reduce the exposure of the dental team during dental procedures. This review aims to evaluate current knowledge on the effect of mouthwash in reducing the oral load of SARS-CoV-2. The article was conducted of two databases and were limited to period January 2018 to May 2023 with combination of the following keywords: “effect” and “mouthwash” and “oral” and “SARS CoV-2”. The results obtained were 21 articles found at the beginning of the search in both databases, and the 11 full text articles were selected for further review and discussion. Chlorhexidine gluconate (0.12%) was effective in reducing salivary SARS-CoV-2 load for at least 60 min. Povidone-iodine 1% oral solutions are effective preprocedural mouthwashes against SARS CoV-2 in dental treatments. Cetylpyridinium Chloride 0,05% could reduce viral load in SARS-CoV-2–positive patients. H2O2 concentrations (1.5% and 3%), verifying a minimal reduction in viral titer after 30s. Benzalkoniumchloride as antiseptic mouthrinse only mildly reduces viral infectivity in vivo, despite its high efficacy in vitro. The use of mouthwash chlorhexidine, povidone-iodine, cetylpyridinium chloride, hydrogen peroxide, benzalkoniumchloride can reduce the number of viruses, one of which is the SARS virus in the oral cavity. Antiseptics are effective in the first stage of contamination, before they enter the cell in the early period.
PENGEMBANGAN MODEL PEMBELAJARAN INKUIRI TERBIMBING PADA KEMAMPUAN LITERASI SAINS SISWA
Authors: Rosita Elia 
Published: July 2023

Penelitian ini bertujuan menganalisis keterlaksanaan model inkuiri terbimbing dan pengaruhnya terhadap kemampuan literasi sains siswa pada materi redoks kelas X.Mia.1 SMA N 4 Muaro Jambi. Pendekatan yang digunakan pada penelitian ini adalah pendekatan campuran (mix method) dengan jenis model sequential exploratoty ( model urutan penemuan). Tekhnik pengambilan sampel dilakukan dengan purposive smpling yaitu X.Mia 1 dan melibatkan 2 orang guru kimia, 32 orang siswa kelas X.Mia.1 dan 32 orang siswa pada saat penelitian. Instrument penelitian dilakukan yaitu lembar observasi, keterlaksanaan model inkuiri terbimbing baik dari guru maupun siswa dan soal tes essay kemampuan tes literasi sains siswa. Untuk melihat pengaruh keterlaksanaan model pembelajaran inkuiri terbimbing dengan kemampuan literasi sains siswa dilakukan uji korelasi produk moment dan uji koefesien determinasi. Berdasarkan hasil penelitian disimpulkan bahwa keterlaksanaan model pembelaajran inkuiri terbimbing berjalan dengan baik dan berpengaruh terhadap kemampuan literasi sains siswa yang ditunjukkan dengan peningkatan hasil presentasi keterlaksanaan oleh siswa setiap pertemuan. Sebesar 60,09% pada pertemuan pertama, 70,04% pada pertemuan kedua dan 81,56% pada pertemuan ketiga. Terdapat pengaruh keterlaksanaan model pembelajaran inkuiri terbimbing terhadap kemampuan literasi siswa dengan nilai rxy = 0,42 dengan kategori hubungan yang sedang.
Campuhan: A New Music Creation | Campuhan: Sebuah Musik Kreasi Baru
Authors: Pratama Gede Made Rama , - Saptono 
Published: July 2023

Campuhan berarti percampuran, yang dalam hal ini campuran suasana hati atau emosional manusia. Campuhan adalah karya musik inovatif yang menggambarkan suasana hati seseorang yang mengalami gangguan mental bipolar (prubahan emosional secara drastis). Selanjutnya diimplementasikannya kedalam sebuah garapan karya musik baru dengan media gamelan semara pegulingan, gamelan angklung klentang, dan gamelan balaganjur. Wujud campuran tiga dasar emosional yaitu netral (ketenangan atau kebahagiaan), depresif (keterpurukan atau kesedihan), dan manik (bersemangat atau ambisi). Struktur garapan Campuhan ini dibagi menjadi tiga bagian, yaitu pertama adalah simbol dari keadaan emosional netral dengan menggunakan media ungkap Semara Pegulingan. Kedua adalah simbol dari keadaan emosional depresif dengan menggunakan media ungkap Angklung Klentang. Ketiga adalah simbol dari keadaan emosional manik dengan media ungkap Balaganjur. Tempat pertunjukan dilaksanakan di Banjar Dinas Antap Kaja, Desa Antap, Kec. Selemadeg, Kab. Tabanan, tepatnya dirumah penata. Garapan karya campuhan ini disajikan dengan melibatkan 13 (tiga belas) orang musisi yang semuanya dari anggota Sanggar Natya Praja dan Sanggar Kapiwara Tabanan, termasuk penata.
Ngunying From Ritual To Music Composition | Ngunying Dari Ritual Menjadi Kompoisisi Musik
Authors: Wardizal Wardizal 
Published: July 2023

“Ngunying” merupakan suatu bentuk tradisi sakral yang tumbuh dan berkembang ditengah kehidupan sosio-kultural masyarakat Kabupaten Bangli. Ngunying adalah suatu ritual sebagai wujud persembahan masyarakat di Desa Bebalang terhadap Sang Hyang Widhi Wasa. Tradisi ngunying merupakan penugrahan oleh Ida Betara Durga, dikarenakan tradisi ngunying tersebut mampu dijadikan sebagai penetralisir alam semesta dari gangguan para bhuta kala. Diyakini setelah pelaksanaan prosesi ini masyarakat akan mendapatkan ketentraman, keseimbangan, dan keharmonisan dalam desa tersebut.. Tradisi Ngunying sebagai upacara ritual dan sakral menarik untuk ditransformasikian menjadi sebuah komposisi musik. Dalam konteks itulah, komposisi musik dengan judul “Ngunying” ini diciptakan untuk keperluan ujian Tugas Akhir pada Program Studi Seni Karawitan Fakultas Seni Pertunjukan ISI Denpasar. Semester genap tahun akademik 2020/2021.. Garapan ini berupa tabuh pategak bebarongan kreasi dengan media ungkap gamelan semar pagulingan saih pitu. Mengingat situasi pandemi Covis-19, maka. Garapan ini menggunakan sample nada gamelan Semar Pagulingan Saih Pitu yang kemudian diproses, diolah atau dituangkan ke dalam aplikasi multimedia FL Studio dan Cubade 5.
Komposisi Karawitan Tabuh Petegak Kreasi “Gacor"
Authors: Putra Mahardika I Kadek 
Published: July 2023

Burung adalah salah satu jenis makhluk hidup yang memiliki keunikan sehingga banyak disegani oleh orang-orang. Keunikan yang dimiliki dari bentuk yang menarik, burung juga memiliki ciri khas tersendiri selain memiliki keindahan fisik, burung juga mampu mengeluarkan suara yang indah. Keindahan burung seperti halnya dari suara burung tersebut yang memiliki kicauan yang sangat indah sehingga dapat menarik perhatian orang-orang untuk menikmatinya. Ciri khasnya dari jenis-jenis burung tersebut, seperti suaranya yang merdu, suaranya yang melengking dan ocehan dari burung tersebut atau yang sering disebut “Gacor”. “Gacor” selain dikarenakan sering berbunyi dari suara aslinya bisa juga bunyi yang dikeluarkan bervariasi, yang mungkin menirukan suara burung yang lain sehingga menambah daya tarik atau keindahan burung tersebut. Demikian pula dalam karya karawitan dengan judul “Gacor” sebagai bentuk alunan irama yang lihai dengan berbagai dinamika keindahan setiap nada. Dengan menonjolkan kelincahan pada kotekan yang dimainkan dengan gamelan bambu menjadikannya ciri dari garapan yang berjudul “Gacor” sehingga penikmat itu sendiri, dapat merasakan keindahan, dari alunan melodi, dinamika dan irama sebuah karya ini, yang dapat menyejukan hati yang penuh dinamis.
The Karawitan Contemporary “Ngontang Gambang” | Karya Karawitan Kontemporer “Ngontang Gambang”
Authors: Negara I Gede Agung Surya 
Published: July 2023

Ngontang Gambang secara definisi memiliki arti dan pesan yang penata rasakan yaitu perbedaan yang jika disatukan akan menghasilkan sesuatu gebrakan baru. Ngontang sebagai sumber imajinasi dan penuanghan ide yang nantinya mampu menerjemahkan suatu peristiwa yang dirasakan penata dan dituangkan ke dalam suatu media ungkap gamelan Gambang dengan menawarkan gagasan pemikiran melalui karya seni. Karya musik kontemporer Ngontang Gambang ini menitikfokuskan pada gamelan Gambang atau tingklik (bahasa Bali) yang menggunakan 3 pasang gamelan Gambang dan 5 buah Kendang. Proses penciptaan karya ini menggunakan tiga tahapan yaitu tahap penjajagan (Exploration), tahap percobaan (Improvisation), dan tahap pembentukan (Forming). Karya musik kontemporer Ngontang Gambang terdiri dari tiga bagian utama, yaitu bagian satu, bagian dua, dan bagian tiga. Karya ini didukung oleh 7 (tujuh) orang penabuh dari Sanggar Mekar Seruni dengan durasi waktu kurang lebih 12 menit.
Nguci a New Musical Creations | Musik Kreasi Baru Nguci
Authors: I Komang Rata sunadi , Suharta I Wayan 
Published: July 2023

Komposisi musik ini memiliki tujuan untuk menuangkan kreativitas dan potensi dalam berkesenian dengan menciptakan karya seni yang berkualitas dan bermutu. Karya yang berjudul tabuh kreasi “Nguci” ini merupakan sebuah garapan karawitan kreasi inovatif yang masih bertitik tolak pada pola-pola tradisi karawitan Bali. Karya ini berawal dari ketertarikan penata pada keindahan suara kicauan burung pleci dan mempunyai siklus suara mulai dari ngeriwik ngalas ,ngerol, ngeplong dan gacor. Sehingga penata mencoba mentranspormasikannya dengan bersifat yang berbeda-beda yang akan menjadi sebuah alunan musik tabuh kreasi yang bernuansa tradisi. Proses penciptaan karya ini melalui 5 tahapan yaitu,tahap inspirasi (ngawirasa), tahap ekplorasi (ngawacak),tahapkonsepsi(ngarencana),tahapeksekusi(ngewangun),tahapproduksi(ngebah).Karya tabuh kreasi Nguci ini terdiri atas tiga bagian yaitu kawitan, pengawak dan pengecet. Dalam penyajiannya karya tabuh kreasi Nguci dimainkan oleh 22 orang pendukung dengan durasi waktu 12 menit. Media yang dipergunakan untuk mengungkapkan karya seni ini adalah gong angklung kebyar.
Intestinal Parasitic Infection Responsible for Undernourishment and Stunted Growth in Children of School Going Age
Authors: Siagian Forman Erwin 
Published: July 2023

Aim: To discuss about the specific characteristics of intestinal parasitic infection that contributes to the formation of stunting.
Discussion: Intestinal parasites infection (IPI) are one of the global utmost health dilemmas, because they put certain vulnerable member of the population, e.g., children, in danger. Global prevalence rate of IPI varied from 30-60%, especially in developing countries located within the region of tropical and subtropical zone that create a definite public health burden, particularly in low- and middle-income countries, including Indonesia. Basically, IPI divided into helminths- and protozoans; each have different and unique characteristics with helminths have a more sophisticated life cycle compare to protozoan. IPI tends to be chronic and sub-clinical, due to the evasion the host's immune system. This chronic IPI affects the host, directly and indirectly, and in long term when it happen during toddlerhood, it contributes to the formation of undernourishment and stunting via certain pathways. Transmission occurs mainly via food contamination; and it is usually always related with daily socio-economic activity. Persistent transmission exists when source of infection available and practice of poor hygiene supports continuous contamination in the environment. By knowing the details of the life cycle of each gastrointestinal parasite, all stake holder can participate in communal effort to break the chain of transmission.
Conclusion: The presence of infected individuals with poor hygiene practice is the main contributor to the existence of persistent transmission in certain environment and this can then play a role in the formation of stunting.
Assessment of Physical Properties of Soils from Different Villages of Osmanabad District, Maharashtra, India
Authors: Padwal Snehal , Swaroop Narendra , Thomas Tarence , Singh Anurag Kumar , Naga Indar Raj 
Published: July 2023

The study was carried out with the objective of analysing the physical properties for determining depth wise nutrient distribution and variation from three different villages of Osmanabad district, Maharashtra. The twenty-seven soil samples were collected from three different villages on different depth that is 0-15 cm, 15-30 cm and 30-45 cm of farmer’s fields.
The colour of the soil sample in dry condition varies at different depths from dark yellowish brown to very dark brown and in wet condition it varies from very dark brown to black. The results revealed that the texture of soil was clay found in all the three respective depths. The Bulk density of different depths varied from 1.17 to 1.21 Mg m-3, Particle density from 2.46 to 2.53 Mg m-3, Percent Pore Space from 40.88% to 48.40 %, Water Holding Capacity from 42.02% to 45.00 %. To maintain fertility of soil, farmers have to test their soils to obtain higher crop yield.
Preformulation Studies of Varenicline for Formulation and Development of a Novel Orally Disintegrating Film
Authors: Amin Prakruti , Patel Manish 
Published: July 2023

Objective: The major goal of pre-formulation research is to create a drug delivery system that is stable, elegant, safe, and effective by determining the drug's kinetic profile, the formulation's compatibility with various excipients, and the physico-chemical characteristics of new drug molecules. This could offer crucial support for executing formulation design or the need for the molecular change. Therefore, in the current study, studies on Varenicline (VAR)'s appropriateness for oral formulation were conducted. Similar to cytisine, VAR functions as a partial nicotine receptor agonist. It blocks alpha-4-beta-2 nicotinic acetylcholine receptor subtypes and is a partial agonist. Through partial agonism, VAR reduces the urge and withdrawal symptoms associated with quitting efforts by inhibiting the dopaminergic activation brought on by smoking. It stops nicotine from stimulating the mesolimbic dopamine pathway, which is linked to nicotine addiction.
Methods: The authenticity of VAR was established by DSC and FTIR spectra. A UV spectrophotometric method was employed for determination of VAR in bulk and active pharmaceutical ingredient (API).
Results: The authenticity of VAR was established by DSC and FTIR spectra. For the determination of VAR in bulk API (active pharmaceutical ingredient), a UV spectrophotometric approach was used. In the concentration range of 5–40 g/ml, the UV technique was linear. The lower% CV values of intraday and interday variability indicate the proposed methodology's robustness. The higher regression coefficient value(0.999) indicates the methodology is robust.
Conclusions: The outcome of the physico-chemical experiments of drug molecule indicates suitability of oral route. Additionally, at different conditions like solid as well as liquid state, the drugmoleculewasobservedstable.
Trends in Opioid Toxicity–Related Deaths in the US Before and After the Start of the COVID-19 Pandemic, 2011-2021
Authors: Gomes Tara , Ledlie Shaleesa , Tadrous Mina , Mamdani Muhammad , Paterson J. Michael , Juurlink David N. 
Published: July 2023

ImportanceOpioid-related harms constitute a major public health crisis in the US, and this crisis has worsened during the COVID-19 pandemic.ObjectivesTo characterize the societal burden of unintentional opioid-related deaths in the US and describe changing mortality patterns during the COVID-19 pandemic.Design, Setting, and ParticipantsA serial cross-sectional study examined all unintentional opioid-related deaths in the US, evaluated annually from calendar years 2011 to 2021.Main Outcomes and MeasuresThe public health burden of opioid toxicity–related deaths was estimated in 2 ways. First, the proportion of all deaths that were attributable to unintentional opioid toxicity by year (2011, 2013, 2015, 2017, 2019, and 2021) and age group (15-19, 20-29, 30-39, 40-49, 50-59, and 60-74 years) were calculated, using age-specific estimates of all-cause mortality as the denominator. Second, the total years of life lost (YLL) due to unintentional opioid toxicity was estimated, overall and by sex and age group, for each year studied.ResultsAmong the 422 605 unintentional deaths due to opioid toxicity between 2011 and 2021, the median age of the individuals was 39 (IQR, 30-51) years, and 69.7% were male. The number of unintentional deaths due to opioid toxicity increased 289% over the study period, from 19 395 (2011) to 75 477 (2021). Similarly, the percentage of all deaths that were attributed to opioid toxicity increased from 1.8% in 2011 to 4.5% in 2021. By 2021, opioid toxicity was responsible for 10.2% of all deaths among those aged 15 to 19 years, 21.7% of deaths among those aged 20 to 29 years, and 21.0% of deaths among those aged 30 to 39 years. The YLL due to opioid toxicity increased 276% over the study period, from 777 597 in 2011 to 2 922 497 in 2021. While YLL plateaued between 2017 (7.0 YLL per 1000) and 2019 (7.2 YLL per 1000), it increased by 62.9% between 2019 and 2021 coincident with the COVID-19 pandemic, reaching 11.7 YLL per 1000 population. This relative increase was similar across all age groups and sexes with the exception of those aged 15 to 19 years, in whom the YLL nearly tripled, from 1.5 to 3.9 YLL per 1000 population.Conclusions and RelevanceIn this cross-sectional study, deaths due to opioid toxicity increased substantially during the COVID-19 pandemic. By 2021, 1 of every 22 deaths in the US was attributable to unintentional opioid toxicity, underscoring the urgent need to support people at risk of substance-related harm, particularly men, younger adults, and adolescents.
Effectiveness of Acupuncture for Prophylactic Treatment of Migraine: A Systematic Review and Bayesian Network Meta‐Analysis
Authors: Song Zi‐Wei , Liu Ya‐Ping , Cui Shuo , Hu Jing , Ma Wen‐Qian , Chen Zhong‐Jie , Huo Jin , Gao Qi , Ma Shu‐Hua , Wang Jing‐Jing 
Published: July 2023

AbstractIt is aimed to evaluate the effectiveness and provide evidence‐based medical support for acupuncture as a prophylactic treatment for migraines. Randomized controlled trials (RCTs) from inception to April 2022 are included in 14 databases. Pairwise meta‐analysis is conducted using STATA software V14.0, while Windows Bayesian Inference Using Gibbs Sampling (WinBUGS V.1.4.3) is applied to generate Bayesian Network Meta‐analysis (NMA) using Markov chain Monte Carlo algorithm. Forty RCTs are included, with 4405 participants. The effectiveness of six acupuncture techniques, three types of prophylactic drugs, and psychotherapy are compared and ranked. Acupuncture outperformed prophylactic drugs in terms of diminishing visual analog scale (VAS) score, migraine attack frequency, and days during the treatment and at the 12‐week follow‐up. At the 12‐week follow‐up, the effectiveness of various interventions is ranked as follows: manual acupuncture (MA) > electroacupuncture (EA) > calcium antagonists (CA) in reducing VAS score; MA > EA > CA in reducing migraine attack frequency; MA > EA > β‐receptor blocker and CA in reducing headache attack days. Acupuncture is a promising treatment for migraine prevention. The best option of acupuncture for improving various migraine outcomes has changed over time. However, the quality of included trials and NMA inconsistency limited the credibility of the conclusion.
A Stretchable, Breathable, And Self‐Adhesive Electronic Skin with Multimodal Sensing Capabilities for Human‐Centered Healthcare
Authors: Hao Yunna , Yan Qiuyang , Liu Huijie , He Xinyang , Zhang Peihua , Qin Xiaohong , Wang Ranran , Sun Jing , Wang Liming , Cheng Yin 
Published: July 2023

AbstractElectronic skins (E‐skins) capable of biomechanical/bioelectrical signal acquisition are intensively pursued for human‐centered healthcare of daily life. For practical use, it is highly desired, yet challenging, to mass‐produce E‐skins that are soft and breathable for wearing comfort, skin‐adhesive for robust signal acquisition, multi‐signal sensing for enhanced healthcare data. Herein, a scalable fabrication strategy for a bioinspired E‐skin (SPRABE‐skin) with a multi‐layered architecture is reported that integrates skin‐like softness, self‐protection, self‐adhesion, breathability, and bimodal sensing in a single patch. The fibrous thermoplastic polyurethane (TPU) scaffold endows the SPRABE‐skin with tissue‐like softness (Young's modulus of 3.36 MPa) and stretchability, good permeability to water vapor, and self‐protection against adverse loading events. A strain sensing layer composed of MXene‐carbon nanotubes@TPU (MXene‐CNT@TPU) composition exhibits ultra‐high sensitivity in a wide sensing range (gauge factor at strain of 485% reaches 63 494). An electrode layer made of MXene‐waterborne polyurethane (MXene‐WPU) provides a highly adhesive electrode‐skin interface, which enables the acquisition of biopotentials, such as electrocardiograph (ECG), electromyograph (EMG), electroencephalo‐graph (EEG), with improved fidelity even under various dynamic interferences. Finally, a SPRABE‐skin based human‐centered healthcare system is demonstrated that realizes the wireless, long‐duration, and dynamic monitoring of ECG and running activities.