bluuebunny/crossref_metadata_2025_split huggingface dataset:
The formation of brain shape in human newborns
Authors: Krohn Stephan , von Schwanenflug Nina , Romanello Amy , Valk Sofie L. , Madan Christopher R. , Finke Carsten 
Published: January 2023

AbstractThe neonatal period represents a critical phase of human brain development. During this time, the brain shows a dramatic increase in size, but it remains largely unclear how the morphology of the human brain develops in earlypost-partumlife. Here we show that human newborns undergo a rapid formation of brain shape, beyond the expected growth in brain size. Using fractal analysis of structural neuroimaging data, we show that brain shape (i) strongly reflects infant maturity beyond differences in brain size, (ii) significantly outperforms brain size in predicting infant age at scan (mean error ~4 days), (iii) detects persistent alterations in prematurely born infants that are not captured by brain size, (iv) is consistently more sensitive to genetic similarity among neonates, and (v) is superior in predicting which newborns are twin siblings, with up to 97% accuracy. These findings identify the formation of brain shape as a fundamental maturational process in human brain development.
Mechanically induced topological transition of spectrin regulates its distribution in the mammalian cortex
Authors: Ghisleni Andrea , Bonilla-Quintana Mayte , Crestani Michele , Fukuzawa Atsushi , Rangamani Padmini , Gauthier Nils 
Published: January 2023

AbstractThe cell cortex is a dynamic assembly that ensures cell integrity during passive deformation or active response by adapting cytoskeleton topologies with poorly understood mechanisms. The spectrin meshwork ensures such adaptation in erythrocytes and neurons. Erythrocytes rely on triangular-like lattices of spectrin tetramers, which in neurons are organized in periodic arrays. We exploited Expansion Microscopy to discover that these two distinct topologies can co-exist in other mammalian cells such as fibroblasts. We show through biophysical measurements and computational modeling that spectrin provides coverage of the cortex and, with the intervention of actomyosin, erythroid-like lattices can dynamically transition into condensates resembling neuron-like periodic arrays fenced by actin stress fibers. Spectrin condensates experience lower mechanical stress and turnover despite displaying an extension close to the contour length of the tetramer. Our study sheds light on the adaptive properties of spectrin, which ensures protection of the cortex by undergoing mechanically induced topological transitions.
Adaptation to an acid microenvironment promotes pancreatic cancer organoid growth and drug resistance in a p53-dependent manner
Authors: Stigliani Arnaud , Ialchina Renata , Yao Jiayi , Czaplinska Dominika , Dai Yifan , Andersen Henriette Berg , Andersson Robin , Pedersen Stine Falsig , Sandelin Albin 
Published: January 2023

AbstractThe harsh environments in poorly perfused tumor regions have been proposed to select for traits that may drive cancer aggressiveness. Here, we tested the hypothesis that tumor acidosis interacts with driver mutations to exacerbate cancer hallmarks, including drug resistance, in pancreatic cancer. We gradually adapted mouse organoids from normal pancreatic duct (mN) and early PDAC (mP, with KRAS G12V mutation and +/- p53 knockout), from pH 7.4 (physiological level) to 6.7, representing acidic tumor niches. Acid adaptation rewired organoid transcriptional activity, increased viability and, strikingly, increased Gemcitabine- and Erlotinib resistance. Importantly, this response only occurred in organoids expressing wild-type p53 and was most pronounced when acid-adapted cells were returned to physiological pH (mimicking increased perfusion or invasion). While the acid adaptation transcriptional change was overall not highly similar to that induced by drug adaptation of the organoids, acid adaptation induced expression of cytidine deaminase (Cda) and ribonucleotide reductase regulatory subunit M2 (Rrm2), both associated with Gemcitabine resistance, and inhibition of these proteins partially restored Gemcitabine sensitivity. Thus, adaptation to the acidic tumor microenvironment increases drug resistance even after cells leave this niche, and this is in part dependent on acid-adaptation-induced transcriptional upregulation ofCdaandRrm2.
When and how sales manager feedback contributes to sales performance: the role of emotional labor and cross-selling
Authors: Shin Yuhyung , Hur Won-Moo , Moon Tae Won 
Published: January 2023

Purpose
This study aims to test the mediating effect of cross-selling behavior (CSB) on the relationship between sales manager feedback (i.e. output and behavioral) and sales performance, and the moderating effect of emotional labor (i.e. deep and surface acting) on this relationship.

Design/methodology/approach
The authors used two-wave multisource data: survey and objective sales performance (sales revenue) data collected from 300 door-to-door salespeople working at a South Korean cosmetics company.

Findings
The relationship between output feedback and sales performance was mediated by CSB. In addition, the positive relationship between output feedback and CSB was weakened by deep and surface acting, whereas that between behavioral feedback and CSB was strengthened by deep acting. Specifically, behavioral feedback had a positive relationship with CSB when salespeople engaged in a high level of deep acting. This relationship was not significant for low and medium levels of deep acting. The authors’ supplementary analyses indicated no significant three-way interaction effect between output feedback, behavioral feedback and emotional labor on CSB.

Research limitations/implications
Data collection from door-to-door salespeople in a single cosmetics company undermines the generalizability of the present findings.

Practical implications
By exploring the boundary conditions that strengthen or weaken the effectiveness of manager feedback, this study provides insights into how the two types of manager feedback can be effectively used to promote CSB and sales performance.

Originality/value
This study offers a nuanced understanding of the relative roles of output and behavioral feedback in CSB and the differential moderating effects of emotional labor on the two types of manager feedback.
Employers’ perspectives of effective continuing education and training in Singapore
Authors: Leow Anthony , Chua Shuyi , Billett Stephen , Le Anh Hai 
Published: January 2023

PurposeEmployers often claim that the lack of employee competence is a limitation in their enterprises’ success and viability. Consequently, employers are important stakeholders in considerations for workforce continuing education and training (CET) policies and practices. Hence, the authors undertook an exploratory investigation to understand how employers perceive provisions of CET offered through tertiary education institutions and how they might be improved.Design/methodology/approachOverall, 40 employers from a range of industry sectors in Singapore were surveyed and interviewed about effective CET for their employees.FindingsThese employers reported preferring one-on-one training in the workplace and being willing to invest in their employees’ training so long employees remained committed to their companies. They value online education, but prefer that it is combined with workplace or face-to-face learning experiences. They proposed effective CET trainers as those with relevant industry knowledge and teaching skills and effective CET learners as those who were self-motivated, goal oriented and open-minded.Originality/valueA study of such nature that focusses on the perspectives of employers, as opposed to employees and educators, has not been undertaken before in Singapore. Given Singapore’s increasing emphasis on lifelong learning and the workplace as a vital site for that learning, the lessons learnt here transcend national boundaries and may serve as a useful reference for other countries that seek to provide inclusive and equitable quality education and lifelong learning for all.
Training prospective technical education graduates for school-to-work transition: insights from university–industry links
Authors: Chukwuedo Samson Onyeluka , Nnajiofor Francisca Nebechi , Auta Mohammed Adamu , Odogwu Ikechukwu Chidiebere 
Published: January 2023

PurposeFollowing the tenets of experiential learning theory (ELT) and social cognitive theory (SCT), this study aims to investigate the influence of higher technology education students' placement experiences (work-related learning by teaching practice [WLTP] and by industry attachment [WLIA]) on learning self-efficacy (LSE) and perceived employability skills (PES) (namely, perceived future network [PFN], perceived expected experiences [PEE]), perceived future personal characteristics (PFPC), perceived future labour market knowledge (PFLMK) and perceived future skills (PFS).Design/methodology/approachUsing two-wave surveys (T1 & T2), data were collected from technical education students (N = 257) in Nigerian universities. At T1, LSE and PES were measured, while WLTP, WLIA, LSE and PES were measured at T2. The repeated measure t-test, and structural equation modelling were applied for statistical analyses.FindingsThe authors found a significant increase in the students' LSE and PES from T1 to T2. Direct associations between WLTP, WLIA, LSE and PES were partly supported. Similarly, WLTP and WLIA have indirect relationships with PES via LSE. However, the result of the indirect effect is partly supported for WLTP and PES relations; but fully supported for WLIA and PES relations.Research limitations/implicationsAlthough this study is not an experimental design to absolutely justify causality, it has provided valuable empirical evidence that added to the extant literature on higher education students' work-related learning, learning ability and employability skills.Originality/valueTo the authors' knowledge, this is the first study to explore the simultaneous influence of two aspects of students' work placement (WLTP and WLAI) on LSE and employability as well as the changes that occur after the placement.
Over 33 years of the hospitality research: a bibliometric review of the International Journal of Contemporary Hospitality Management
Authors: Sharma Gagan Deep , Taheri Babak , Gupta Mansi , Chopra Ritika 
Published: January 2023

Purpose
This paper aims to proffer a broad overview of publications in the International Journal of Contemporary Hospitality Management (IJCHM) by conducting bibliometric analyses for the duration ranging from 1989 to 2022.

Design/methodology/approach
The research approach analyses the top authors, publications, most collaborative countries and top co-occurring keywords and significant themes published in IJCHM with the help of the Scopus database. The study entails performance analyses on IJCHM. A de-duplicating process was used to study the evolution of themes, so that the keywords identified from co-occurrences of authors’ keywords and thematic evolution map were refined to first- and second-order themes, further leading to the development of inductive analysis proposing aggregate themes.

Findings
The findings of this study not only help paint a comprehensive picture of the customer experience, but also illustrate how topics have evolved in the literature and reveal the most relevant upcoming fields of research. The thematic evolution map reveals thematic areas. There is evidence of contributions by authors across the world and spanning a multitude of themes such as business ethics, corporate and firm performance, stakeholders and avenues for the management of disruption, specifically in times of the COVID-19 pandemic outbreak.

Research limitations/implications
Significant trends in authors, publications, nations, authors’ keywords and themes as uncovered by this study can greatly help budding authors understand the expectations and emerging research themes that define the IJCHM.

Originality/value
Through extensive bibliometric analyses, this study has created a historical log of the publications in IJCHM. It has identified the key research trends for future research and presented a conceptual framework based on the keyword analysis map and thematic evolution.
The digitalisation as gender equaliser? The import and export of digitally delivered services in shaping female entrepreneurship in European countries
Authors: Gaweł Aleksandra , Mińska-Struzik Ewa 
Published: January 2023

PurposeThe article examines whether cross-border trade in digitally delivered services (DDSs) has an influence on European female entrepreneurship. Two research questions were asked to assess the potential impact of trade in DDSs both on the import and export sides.Design/methodology/approachTo answer the research questions, the panel data for 26 European countries for the years 2008–2019 were implemented to estimate panel regression models. Based on the results of variance inflation factors (VIFs) and Breusch–Pagan and Hausman tests, the estimations of panel models were conducted for female entrepreneurship as a dependent variable and measures of import and export of digitally delivered services as independent variables.FindingsThe imports of digitally delivered services positively affect female entrepreneurship in European countries, whilst the impact of the export of digitally delivered services is statistically insignificant. The possibility of being a customer of digitally delivered services through its import may become a gender equaliser in entrepreneurship. However, as differences in digital competencies and growth intentions prevent women from acting as the providers of digitally delivered services, the export of DDSs can sustain the existing gender gap in entrepreneurship.Practical implicationsThe research findings provide the added value in the field of female entrepreneurship, referring to institutional theory and human capital theory. The import of DDSs seems to support female entrepreneurs through the reduction of cultural distance, whilst the human capital theory gains the perspective of limited digital competencies needed to export DDSs as a pathway to the internationalisation of women's ventures. The practical implications for trade policy, digitalisation and gender equality should aim not only at supporting women's export propensity, but should also focus on the development of their digital competencies.Originality/valueInstead of commonly used perspective of international entrepreneurship, the authors implemented the lens of cross-border trade to check whether there is a linkage between internationalisation, measured by imports and exports of DDSs and female entrepreneurship. Trade economists neglect the gender dimension in their studies of pro-growth internationalisation. In contrast, research on female entrepreneurship does not consider the potential of cross-border trade in DDSs as a gender equaliser.
Systems thinking for systems leadership: promoting competency development for graduate students in sustainability studies
Authors: Talley Emily K. , Hull R. Bruce 
Published: January 2023

Purpose
This paper aims to offer a case study for teaching specific systems thinking competencies that promote leadership for systems change. It uses leadership as a novel way to identify and organize systems thinking competencies that are important for successful multistakeholder collaboration.

Design/methodology/approach
Qualitative and quantitative approaches were used to assess learning outcomes across four cohorts of graduate students – with approximately 30 students per cohort – from 2017 to 2020 in the USA. The study examined a one-month-long assignment, out of a year-long program, that focuses on systems leadership for climate change.

Findings
Our findings demonstrate that higher education programs can successfully build these competencies in sustainability students and professionals. Our pedagogical approach enhances students’ systems thinking and leadership competencies.

Originality/value
We advance the understanding and teaching of systems thinking by integrating it with the direction, alignment and commitment model of leadership. Reframing systems thinking through the lens of leadership offers an important innovation and focus to the theory of systems thinking, and the pedagogy of building competencies sustainability professionals need.
Multilevel governance, community and emergency management during the pandemic: migrants in Japan
Authors: Milly Deborah J. 
Published: January 2023

PurposeBuilding on perspectives from the study of multilevel governance, migrants' inclusion and emergency management, this article asks how differences across national regulations for foreign residents, work eligibility and access to national emergency supports intersected with local approaches in responding to migrants.Design/methodology/approachThis article examines national policy adjustments and parallel subnational governance early in the pandemic for three groups of foreign residents: international students, technical interns and co-ethnics with long-term visas, primarily Brazilians and Peruvians. It uses Japanese-language documents to trace national policy responses. To grasp subnational governance, the article analyzes coverage in six Japanese regional newspapers from northern, central and western Japan, for the period of April 1 to October 1, 2020.FindingsNational policies obstructed or enabled migrants' treatment as members of the local community but did not dictate this membership, which varied according to migrant group. Migrants' relationship to the community affected available supports.Originality/valueThe article brings together perspectives on multilevel governance, emergency management and migrants' inclusion. It exposes how different migrant groups' ties to the local community affected access to supports.
The influence of the physical work environment on retail employees
Authors: Kearney Treasa , Coughlan Joseph , Kennedy Aileen 
Published: January 2023

Purpose
Despite repeated calls for research to explore the effects of the physical work environment on employees within the servicescape literature, gaps in knowledge remain. There is a need to understand the nature, influence and impact of environmental stimuli (e.g. music, colour) on employees. Extant research remains ambiguous on whether employees perceive individual stimuli within their work environment or perceive and interact with their physical work environment as a holistic experience. This study aims to explore the influence of environmental stimuli on employees within their physical work environment and the effect on their satisfaction and loyalty.

Design/methodology/approach
A two-stage approach was applied, with expert interviews followed by an employee survey which was analysed using structural equation modelling.

Findings
This research validates a holistic physical work environment construct, consisting of five dimensions: Colour & Design, Cleanliness & Odour, Music, Lighting and Layout. This study provides empirical evidence of the impact of environmental work stimuli on employee satisfaction, a relationship which is mediated by pleasure.

Originality/value
Firstly, this study examines the neglected side of servicescape research: employees. Secondly, the findings support the view that employees do not perceive individual elements of their physical work environment as distinct and separate elements but rather perceive, and interact with, their physical work environment as an integrated whole. Evidence of how environmental stimuli at work increase employee job satisfaction is a key takeaway for retail practitioners focussed on improving service experiences for all actors.
The use of textile materials for respiratory protection in times of pandemics: a systematic review and analysis
Authors: Paim Ana Aline Mendes , de Andrade Morgana Carneiro , Steffens Fernanda 
Published: January 2023

Purpose
Given the COVID-19 Pandemic outbreak and the role of medical textiles for protection, this study aims to identify the leading research foci on using textile materials for personal protection in pandemic situations.

Design/methodology/approach
A systematic review and systemic analysis of the literature on the subject were performed using the process knowledge development – constructivist (ProKnow-C) methodology.

Findings
A bibliographic portfolio with 16 relevant studies was obtained. This portfolio represents the main focus of this research field, including the main filtration mechanisms, ways of disinfecting N95 respirators and proposed methods to evaluate the filtration efficiency of different materials with potential for mask development.

Originality/value
To the best of the authors’ knowledge, this is the first time the ProKnow-C methodology was used in the textile field. Thus, future studies can benefit from using the Proknow-C for selecting and analyzing relevant textile studies following a systematic approach.
Study of lawsone and its modified disperse dyes derived by triple cascade reaction: dyeing performance on nylon and polyester fabrics
Authors: Patel Nilam C. , Desai Dipen H. , Patel Paresh N. 
Published: January 2023

Purpose
This paper aims to develop a novel protocol for the synthesis of disperse dyes derived by a triple cascade reaction with lawsone in presence of Zn acetate as a catalyst. The developed novel scaffolds have efficient dyeing properties on nylon and polyester fibers.

Design/methodology/approach
This report demonstrates an effectual triple cascade protocol for the synthesis of novel disperse dyes derived from various polynuclear carbaldehyde, urea and lawsone. The Zn acetate was found to be an effective catalyst for this reaction. Their dyeing performance has been studied on nylon and polyester fabrics. The wash fastness, sublimation fastness, color assessment, determination of percentage exhaustion and fixation properties were applied to both the dyed fabrics.

Findings
The obtained results indicate that the Zn acetate is an efficient catalyst for the developed triple cascade protocol. The prepared novel disperse dye greatly impacted their dyeing properties on nylon and polyester fibers. They have shown brilliant shades, higher affinity, adsorption capacity, superior tinctorial strength than the lawsone. The percentage exhaustion value, fixation value, color strength (K/s) value, washing and sublimation fastness properties have been found very well in all dyed nylon samples compared to polyester samples. These results discloses that these disperses dyes are very useful to the growing importance of nylon and polyester fibers.

Research limitations/implications
The present protocol synthesizes the racemic mixture of the prepared molecules.

Practical implications
Developed protocol can be used for various other triple cascade processes. Also these molecules can be used for dyeing of other fabrics.

Social implications
With the help of commercialization of prepared molecules, it may provide the better alternative of the current disperse dyes. This may affect the various segments of society.

Originality/value
This report represents a novel protocol for the synthesis of modified novel disperse dyes with an efficient dyeing properties on nylon and polyester fibers.