bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sistem Electronic Nose Untuk Deteksi Aroma Pada Fasilitas Kamar Mandi Berbasis IoT
Authors: Erwanto Danang , Wahyudi Deka , Fatkhur Rizal Royb 
Published: May 2023

Internet of Things (IoT) dan Electronic nose (E-Nose) serta penggunan Fuzzy Logic, merupakan teknologi yang saat ini berkembang. Pada teknologi berbasis IoT, keseluruhan aktivitas yang dikerjakan oleh manusia, bisa dikendalikan dengan memanfaatkan jaringan internet. Hal ini dimanfaatkan untuk metode alternatif mengendalikan bau untuk kebersihan toilet, yang dapat dimonitoring melalui jaringan internet, ESP32 sebagai mikrokontroler, dan sensor MQ-3, MQ-135, MQ-137 dan sensor DHT11. Tujuan dari penelitian ini adalah membangun perangkat lunak untuk memantau kebersihan toilet melalui smartphone menggunakan aplikasi Telegram. Sistem ini digunakan untuk mengetahui efisiensi dalam mengendalikan bau toilet dengan memanfaatkan IoT. Hasil penelitian ini berupa sistem untuk mengontrol kebersihan toilet berbasis IoT dengan memanfaatkan jaringan internet sehingga dapat memantau kebersihan toilet melalui smartphone. Pemantauan ini bisa dilaksanakan dimanapun selama sistem dapat terhubung dengan jaringan internet. Dari penelitian ini sistem mampu mengirim data ke smartphone dengan baik melalui internet tanpa terjadi delay dan error data. Selama kadar alkohol, amonia dan karbondioksida diambang batas wajar tidak akan muncul pemberitahuan lewat telegram ataupun buzzer. Sistem telah berfungsi sesuai dengan yang dirancang, yaitu informasi data yang diperoleh sesuai dengan data yang dikirimkan oleh perangkat keras.
CARACTERÍSTICAS DO USO DOS MÉTODOS CONTRACEPTIVOS EM MULHERES NA IDADE FÉRTIL
Authors: Fernandes Santos Isabella Stehling , Aparecido de Carvalho Gabriel , Cristine Marini Danyelle 
Published: May 2023

Um número considerável de mulheres engravidam por acidente ou pelo uso incorreto do contraceptivo, que pode ocorrer por falta de uma orientação adequada, o que acaba sendo uma gravidez não planejada e indesejável. Hoje mais de 80 milhões de mulheres passam por essa situação, e esse número só tem aumentado. Um método seguro para evitar a gravidez é a pílula oral, que possui de 0,1 a 3% de chance de falha apenas, e a camisinha que além de prevenir contra uma gravidez indesejada previne também contra doenças sexualmente transmissíveis. O objetivo deste trabalho foi avaliar o método contraceptivo utilizado em mulheres com idade fértil, bem foi verificar o conhecimento sobre eles e o motivo que a fez escolher por este método. Tratou-se de um estudo descritivo transversal que utilizou como instrumento um questionário on-line com 34 perguntas tendo questões abertas e fechadas, em mulheres acima de 18 anos e que estão no período fértil. Observou-se que a idade da primeira relação sexual foi de maioria com 17 anos e o contraceptivo usado por elas na primeira relação foi à camisinha, seguido de camisinha mais pílula oral. Quando se associa o contraceptivo com o cigarro ocorre um aumento do risco de ter um AVC. Mesmo estando em idade fértil 29 das entrevistadas não faz uso de nenhum método contraceptivo. E neste estudo o contraceptivo de primeira escolha das entrevistadas é a camisinha associada com a pílula oral. Quando se associa o contraceptivo com o cigarro ocorre um aumento do risco de ter AVC.
Uso de semilla de Mangífera índica como coagulante natural para tratamiento de potabilización
Authors: Oliveros Godínez Irasema Karina 
Published: May 2023

En muchas zonas rurales de Guatemala, el servicio de agua se presta de forma intermitente y no cumple con las características para ser agua potable, principalmente por la presencia de altas concentraciones de turbiedad y color. Estas características del agua pueden ser reducidas a través de la coagulación-floculación-sedimentación con coagulantes que pueden ser de tipo orgánico e inorgánico, siendo los coagulantes inorgánicos los más utilizados, por la poca información científica que existe en relación con los coagulantes naturales. Esta investigación analizó el porcentaje de sustitución o combinación del coagulante a base de molienda de semilla de Mangífera índica (mango) por el sulfato de aluminio Al2(SO4)3. Para el estudio se utilizó la prueba de jarras, debido a que, simula el proceso de coagulación-floculación que se lleva cabo en una planta potabilizadora. De acuerdo con el estudio realizado el coagulante natural a base de molienda de semilla de Mangífera índica alcanzó un porcentaje de remoción de turbiedad de 93.21% para un rango de turbiedad de 215 NTU a 603 NTU, asimismo se determinó que la combinación que mejor eficiencia reportó durante el estudio es la realizada con 40% de sulfato de aluminio Al2(SO4)3, mezclado con 60% de coagulante natural a base de semilla de Mangífera índica (mango). Esta combinación de coagulante natural e inorgánico logró valores de turbiedad residual por debajo de las 5 NTU que requiere la norma guatemalteca para consumo humano (COGUANOR NTG 29001), sin embargo, su aplicación se ve limitada por su costo de producción.
Análisis de la estimación del caudal del río Cabuz utilizando lluvia del modelo WRF y lluvia registrada
Authors: González Raxjal Wilder Eduardo 
Published: May 2023

El uso de modelos numéricos del tiempo es una herramienta vital para todo Servicio Meteorológico Nacional. El modelo de Investigación y Pronóstico del Tiempo (WRF, por sus siglas en inglés) es un modelo numérico meteorológico que en este estudio se utiliza como herramienta para estimación de caudales utilizando su lluvia pronosticada. En este estudio se hace énfasis en la importancia que tiene el uso de los modelos numéricos meteorológicos como herramientas en la hidrología, principalmente aplicado a cuencas que presentan registros de inundaciones que causan severos daños a la población que se ubica en ellas, tal es el caso del río Cabuz de Guatemala, donde se aplica este estudio. Se espera que esta primera aproximación del modelo permita implementar en un futuro sistemas de alerta temprana que colaboren con la reducción de desastres en la cuenca del río Cabuz. En este estudio se utilizó un modelo meteorológico y uno hidrológico para realizar un análisis de lluvia-escorrentía. Se seleccionaron ocho eventos de lluvias intensas del 2010 para calibrar la cuenca utilizando la metodología del hidrograma unitario sintético del SCS. Se modelaron los eventos de lluvia seleccionada del 2014 utilizando como base las condiciones de calibración de la cuenca. Los resultados muestran que los hidrogramas de lluvia pronosticada por el modelo WRF y la lluvia registrada tuvieron variaciones significativas, las cuales se atribuyen a la resolución utilizada en el modelo o a la influencia que puede generar la retención potencial inicial en la cuenca, por lo que se recomienda profundizar estudios en estos dos aspectos para reducir estas diferencias encontradas.
Escenarios de erosión en la cuenca del río Coyolate
Authors: Estrada Mendez Mynor Roberto 
Published: May 2023

La cuenca del rio Coyolate es de importancia económica y ecológica para Guatemala, en esta se producen los cultivos con mayor aporte al PIB nacional siendo estos la caña de azúcar, maíz, banano, café y hule entre otros. El estudio generó tres escenarios de erosión hídrica utilizando cuatro niveles de erosión nula a ligera, moderada, fuerte y muy fuerte, que corresponden a tasas de erosión menor a 10, de 10 a 50, de 50 a 200 y mayor a 200 toneladas por hectárea anuales. En este se determinó la intensidad de uso de los suelos de la cuenca, comparando su capacidad de uso con su uso actual utilizando el modelo USLE para el cálculo de la erosión hídrica. Los escenarios presentaron las siguientes coberturas: a) 96% agricultura, 1.5% bosque y 2.5% otros usos; b) 65% agricultura, 28% bosque y 7% de otros usos; y c) 69% agricultura, 29% bosque y el 2% otros usos. El estudio concluyó que una de las principales causas de la erosión hídrica en la cuenca del río Coyolate es el uso inadecuado de sus suelos sin tomar en cuenta su capacidad de uso y características geomorfológicas. Se encontró que, aunque se incrementara el área para agricultura, una adecuada distribución de uso generaría menor erosión hídrica. Para mitigar la erosión hídrica en la cuenca, se debe mejorar su gestión, adecuando el uso de sus suelos e implementando prácticas para su conservación.
Estrategias nutricionales en adultos con diabetes mellitus
Authors: Villacis Fiallos Angelo Joel , Arteaga Almeida Cristina Alexandra 
Published: May 2023

La diabetes mellitus tipo 2 es una de las principales enfermedades que afecta a la sociedad ecuatoriana, llegando a afectar a 1.4 millones de ecuatorianos en la actualidad, situación que se agudiza como resultado de la práctica de hábitos nutricionales no saludables, que conllevan a un incremento de personas con sobrepeso y obesidad, debiéndose destacar el incremento de la población adulta mayor con estos problemas, además de las costumbres sedentarias que inciden en el aumento sostenido de casos de diabetes mellitus tipo 2. Es una prioridad para las autoridades sanitarias desarrollar estrategias nutricionales para adultos mayores afectados por esta enfermedad, destacándose la importancia de ejecutar acciones de educación para la salud que incidan positivamente en el cambio de malos hábitos nutricionales y el incremento sistemático de la actividad física como alternativas plenamente viables para reducir los casos de diabetes mellitus tipo dos en la población adulta. La metodología utilizada en el desarrollo del artículo científico corresponde a una revisión bibliográfica. Concluyendo que las estrategias nutricionales se enfocan en la transformación de los estilos de vida, a partir del incremento de la actividad física, la reducción de la ingesta de carbohidratos y la adopción de una nutrición saludable rica en proteínas y fibra, pero baja en grasas.
Evaluation of Soil Physico-Chemical Properties in Pre and Post Flood Conditions at Thatta Sindh Pakistan
Authors: Chohan Muhammad , Panhwar Riaz Noor , Soomro Abdul Fatah , Kaloi Ghulam Mohyuddin , Mari Ali Hassan , Bhatti Illahi Bux , Gadehi Mumtaz Ali 
Published: May 2023

The heavy rainfall caused biggest ever natural rain flood in River Indus in the history of Pakistan during 2010. The deltaic district Thatta of Sindh Pakistan hit by flood with breach came out at Dyke near Thatta city on right bank of River Indus. The soil sampling was carried out in month July 2010 prior to flood for routine soil analysis. After flood again soil samples from 13 same sites of pre flood spots were collected at two depths, 0-15 and 15-30 cm. Aim was to observe soil physic-chemical properties and nutrient status of pre-flood and post flood conditions. Soil sand pH and SAR were found significantly higher in post-flood conditions whereas clay and OM were found high in pre-flood conditions. The nutrients status of N, P, Ca and Mg were depleted however K remained satisfactory in post-flood conditions. In post flood conditions the pH and SAR were positive and significantly correlated with each other indicated disperse of soil. The information obtained from this study will be helpful to develop flood qualification strategies and proper management of soil.
Effect of Fluorescent-Producing Rhizobacteria on Cereal Growth Through Siderophore Exertion
Authors: Ehsan Shabana , Qureshi Amjad , Chaudhary Neelam , Ali Asif , Niaz Abid , Javed Hina , Ijaz Fraza , Anwar Shakeel Ahmed 
Published: May 2023

Despite soil having an abundance of iron (Fe), it is unavailable for proper plant growth and development. One of the mechanisms plants use to deal with iron deficiency is the uptake of iron by chelating phytosiderophores. Pseudomonas fluorescence can produce pyoverdine-type siderophore and has potential application in agriculture as an iron chelator. Therefore, bacterial isolates collected from different areas of district Faisalabad were screened for their fluorescent, siderophore production and indole acetic acid equivalents. After selecting efficient strains from a screening test, they were evaluated for improving wheat and maize production under field conditions. The results showed that out of 15 isolates, 7 were found to have significant plant-beneficial microbial traits. Efficient strains promoted grain yield by 24.2% and 20.2%, plant height by 30.9% and 23.7%, total grain weight by 25.3% and 13.4% over control in wheat and maize, respectively. Similarly, significant improvements in the number of grains per cob/spike were also observed. Analyses of grain iron contents depicted 67% increase as compared to control in for maize. Therefore, based on the results, it is concluded that bio-fortification of cereal crops through fluorescent producing siderophoric microbes is an effective strategy favorable for plant growth and development through nutrient solubilization/mobilization.
L’entrée dans la vie adulte dans les départements et régions d’outre-mer : plus tardive aux Antilles qu’à La Réunion
Authors: Floury Élodie , Breton Didier , Marie Claude-Valentin 
Published: May 2023

À partir des données de l’enquête Migrations, famille et vieillissement (MFV) réalisée en 2020-2021 par l’INED, cet article propose un aperçu du processus d’entrée dans la vie adulte chez les jeunes natifs de Guadeloupe, Martinique, Guyane et La Réunion. Sont étudiés les cinq événements principaux de cette période de vie entre l’enfance et l’âge adulte : fin des études, décohabitation parentale, mise en union, parentalité et premier emploi. Une analyse inédite de l’obtention ou non du permis de conduire est également menée. Les résultats montrent des trajectoires différenciées selon les départements, les niveaux d’études et selon le sexe.
Effect of hydroalcoholic leaf extract of Cassia fistula L. on type II collagen-induced arthritis in rats
Authors: Mehta Vineet , Nagu Priyanka , Parashar Arun , Chaudhary Manjusha 
Published: May 2023

Objective:
To explore the effect of Cassia fistula on collagen II-induced arthritis in rats.

Methods:
The effect of 250 and 500 mg/kg chloroform and hydroalcoholic extract of Cassia fistula leaf on collagen II-induced arthritis was investigated by evaluating paw volume, arthritis index, spleen index, and biochemical parameters. Histopathological analysis and docking study were also performed.

Results:
A dose-dependent reduction in paw volume, arthritic index, and spleen index was observed following oral administration of the chloroform and hydroalcoholic extracts. Treatment with Cassia fistula extracts reduced tumor necrosis factor-α, interleukin (IL)-1β, IL-6, prostaglandin E2, aspartate aminotransferase, alanine aminotransferase, total leucocyte count, and erythrocyte sedimentation rate while increasing IL-10 level. In addition, Cassia fistula extracts improved joint architecture, and prevented cartilage and bone destruction. Docking analysis demonstrated that the physcion, 1-octacosanol, 5,3',4'-trihydroxy-6-methoxy-7-O-α-L-rhamnopyranosyl-(1,2)-O-β-D-galactopyranoside and scopoletin may be responsible for the anti-arthritic effect of Cassia fistula.

Conclusions:

Cassia fistula suppresses the progression of collagen II-induced arthritis by lowering the inflammatory factors, decreasing paw volume and arthritic index, and alleviating joint architecture. However, further studies are required to confirm the bioactive molecule responsible for the anti-arthritic potential of Cassia fistula.
Anti-inflammatory effects of Solanum procumbens on a low dose complete Freund's adjuvant-induced arthritis rat model
Authors: Do Xuan-Hai , Nguyen Trong Nghia , Dang Thanh Chung , Nguyen Thi Thanh Mai , Nguyen Trung Nhan , Do Van Nhat Truong , Le Huu Tho , Nguyen Xuan Hai , Dang Hoang Phu , Nguyen Giang-Linh , Hoang Dinh-Khanh , Le Van-Quan , Can Van-Mao 
Published: May 2023

Objective:
To investigate the anti-inflammatory and analgesic effects of Solanum procumbens on complete Freund's adjuvant-induced arthritis rat models.

Methods:
We isolated and identified five compounds in the ethanol-soluble Solanum procumbens extract (SP) with anti-inflammatory effects, including ursolic acid, β-sitosterol, hexadecanoic acid, cis-vaccenic acid, and vanillic acid. Additionally, we investigated the anti-inflammatory effects of SP on rheumatoid arthritis symptoms, including paw volumes, local temperatures, withdrawal latency, and mechanical withdrawal threshold at the hind paw and white blood cell (WBC) number from complete Freund's adjuvant-induced arthritis rat models.

Results:
We have successfully established a complete Freund's adjuvant-induced arthritis rat model at a low dose (1 mg/mL). SP extract significantly reduced paw volumes (P<0.05), prolonged withdrawal latencies (P<0.05), decreased local temperature, and increased the mechanical withdrawal threshold (P<0.05), but only SP extract at the dose of 300 mg/kg significantly decreased WBC numbers.

Conclusions:
SP extract could be a potential medication candidate with anti-inflammatory effects for arthritis, but it requires further investigation into the mechanism of the SP and its effectiveness on other models as well as clinical trials.
Single-Session Prophylactic Pan-Retinal Photocoagulation in Moderate Nonproliferative Diabetic Retinopathy in Low-Resource Settings
Authors: Fathalla Ahmed Mahmoud Fahmy , Abdelazeem Khaled , Kedwany Salma Mohamed , Mohamed Tarek Ahmed , Abdel-Radi Mahmoud , Mostafa Magdi Mohammad , Wasfi Ehab , El-Sebaity Dalia M. 
Published: May 2023

Purpose:
To study patient's acceptability and safety of offering a prophylactic early single session of pan-retinal photocoagulation (PRP) for moderate nonproliferative diabetic retinopathy (NPDR) in selected patients.

Settings and Design:
Mixed observational and interventional study.

Patients and Methods:
The observational study included 82 eyes of 68 patients presenting with proliferative diabetic retinopathy (PDR) or its complications and the interventional study included 48 eyes of 48 patients with moderate NPDR who were offered a single session PRP because they were unlikely to comply with the follow-up protocol and were at higher risk of diabetic retinopathy (DR) progression.

Results:
The observational study showed that nearly 51% of patients had no idea about the DR screening protocols, 47.5% of included eyes presented with vitreous hemorrhage, 30.5% with tractional retinal detachment, and 22% with retinal neovascularization. The interventional study showed that minor patients' complaints were reported such as night vision problems, flashes, and peripheral field defects. There was no significant change in the mean preoperative logarithm of the minimum angle of resolution (logMAR) corrected distance visual acuity (CDVA) over time throughout the study (P = 0.951). At the end of follow-up, 89.5% of included eyes showed no loss of any lines of their preoperative logMAR CDVA and 10.5% lost only one line. All eyes remained in the same stage of moderate NPDR with no signs of progression to severe or very severe NPDR or proliferative DR.

Conclusion:
Prophylactic early PRP is an acceptable, safe, and satisfactory procedure for patients with moderate NPDR in low-resource settings.
Comparison of renal artery Doppler parameters of monochorionic diamniotic twin pregnancies with and without twin-to-twin transfusion syndrome
Authors: Zarean Elaheh , Farahbod Farinaz , Khanjani Somayeh , Zanbagh Leila , Tarrahi Mohammad Javad , Veisian Mehrnaz 
Published: May 2023

Background:
Monochorionic diamniotic (MCDA) twin pregnancies are considered high-risk for several reasons, especially the risk of twin-to-twin transfusion syndrome (TTTS). Renal artery Doppler (RAD) is reported as a useful tool for predicting oligohydramnios in singleton pregnancies. We aimed to compare the RAD indices between MCDA twins with and without TTTS.

Materials and Methods:
In this case–control study, all pregnant women aged 18–38 years, with gestational age ≥ 18 weeks, who were referred to two Prenatal Clinics, Alzahra and Beheshti Educational Hospitals, affiliated to Isfahan University of Medical Sciences, Isfahan, Iran, October 2020–March 2022 were enrolled; the women with MCDA twin pregnancies complicated by TTTS (case group, n = 12) and without TTTS (control group, n = 24). For each twin, biometric analysis, fetal weight, and Doppler study of fetal arteries, including RAD, middle cerebral artery (MCA), umbilical artery, and ductus venosus were performed. Peak systolic velocity, Pulsatility index (PI), resistance index (RI), and systole/diastole (S/D) were measured for all arteries.

Results:
The donors of the case group had a lower mean MCA S/D (4.48 ± 1.89) than the control group (6.48 ± 1.97) (P = 0.01) and higher mean umbilical parameters, including PI, RI, and S/D (P < 0.05). The recipients of the case group had a lower mean renal PI than the control (P = 0.008) and lower mean MCA PI, RI, and S/D (P < 0.05). The donor group had a higher mean umbilical RI and S/D than the recipient twin, while the mean fetal weight of the recipient group was higher (P < 0.05).

Conclusion:
Comparing the RAD parameters between the twins with and without TTTS in the present study did not identify significant results, which rejected the primary hypothesis. Among all RAD parameters, the only significant difference observed in the present study was the lower RAD PI in RT, which cannot suggest this measurement as a valuable tool for the prediction of TTTS in MCDA twins. Therefore, the results of the present study failed to show the additional value of RAD, compared with the conventional Doppler examination of fetal arteries. Further studies are required to prove this conclusion.
Efficacy of metformin adjunctive therapy as the treatment for non-diabetic patients with advanced non-small cell lung cancer: A Systematic review and Meta-analysis
Authors: Duan Xueyu , Liao Binbin , Liu Xiaobo , Chen Ruixiang 
Published: May 2023

Background:
Currently, the anticancer effects of metformin on different types of lung cancer have been frequently studied. However, the relationship between metformin and prognosis in nondiabetic patients with lung cancer remains controversial. To systematically evaluate the efficacy of metformin adjunctive therapy as the treatment for nondiabetic patients with advanced non-small cell lung cancer (NSCLC) to provide an evidence-based reference for clinical medication.

Materials and Methods:
The literatures related to Phase II or III randomized controlled trials (RCTs) of metformin adjunctive therapy in nondiabetic patients with advanced NSCLC, including EMBASE, PubMed, the Cochrane Library, and Scopus database, were retrieved by computer, and the search time ranged from January 2017 to August 2022. The risk of bias assessment tool recommended by Cochrane Systematic Evaluator Manual 5.1.0 was used to evaluate the quality of the RCTs included. Rev Man 5.3 software and STATA15.0 were used for meta-analysis.

Results:
A total of 8 studies were included (925 patients). Meta-analysis results showed that there were no significant differences in progression-free survival (PFS) (hazard ratio [HR] = 0.95, 95% confidence interval [CI]: 0.66–1.36, P = 0.77), overall survival (OS) (HR = 0.89, 95% CI: 0.61–1.30, P = 0.55, n =7), objective response rate (ORR) (odds ratio [OR] = 1.37, 95% CI: 0.76-2.46, P = 0.30), and 1-year PFS rate (OR = 0.87, 95% CI: 0.39-1.94, P = 0.73, n = 3). Sensitivity analysis showed that PFS and OS indexes were stable.

Conclusion:
Metformin adjunctive therapy can improve the DCR of nondiabetic patients with advanced NSCLC. In addition, the patients cannot obtain a prolonged PFS, OS, 1-year PFS rate, and higher ORR rate.