bluuebunny/crossref_metadata_2025_split huggingface dataset:
Toward a simple and accurate Lagrangian-based error estimator for the BDF algorithms and adaptive time-stepping
Authors: Wang Yazhou , Luo Dehong , Zhang Xuelin , Wang Zhitao , Chen Hui , Zhang Xiaobo , Xie Ningning , Mei Shengwei , Xue Xiaodai , Zhang Tong , Tamma Kumar K. 
Published: September 2023

Purpose
The purpose of this paper is to design a simple and accurate a-posteriori Lagrangian-based error estimator is developed for the class of backward differentiation formula (BDF) algorithms with variable time step size, and the adaptive time-stepping in BDF algorithms is demonstrated for efficient time-dependent simulations in fluid flow and heat transfer.

Design/methodology/approach
The Lagrange interpolation polynomial is used to predict the time derivative, and then the accurate primary result is obtained by the Gauss integral, which is applied to evaluate the local error. Not only the generalized formula of the proposed error estimator is presented but also the specific expression for the widely applied BDF1/2/3 is illustrated. Two essential executable MATLAB functions to implement the proposed error estimator are appended for practical applications. Then, the adaptive time-stepping is demonstrated based on the newly proposed error estimator for BDF algorithms.

Findings
The validation tests show that the newly proposed error estimator is accurate such that the effectivity index is always close to unity for both linear and nonlinear problems, and it avoids under/overestimation of the exact local error. The applications for fluid dynamics and coupled fluid flow and heat transfer problems depict the advantage of adaptive time-stepping based on the proposed error estimator for time-dependent simulations.

Originality/value
In contrast to existing error estimators for BDF algorithms, the present work is more accurate for the local error estimation, and it can be readily extended to practical applications in engineering with a few changes to existing codes, contributing to efficient time-dependent simulations in fluid flow and heat transfer.
Co-production in clinical practice: a case-study of engagement with patients with dementia and Huntington's disease to develop meaningful cognitive activities
Authors: Girardi Alessandra , Webb Elanor , Stewart Inga , Stokes Simon , Breen Kieran 
Published: September 2023

PurposeThe development and clinical application of digital devices to support individuals with dementia can be challenging due to difficulties meeting the needs of a patient population with largely heterogeneous and progressive symptoms. Memjo Ltd has developed a digital interactive prototype tablet to promote cognitive stimulation and reminiscence. This proof-of-concept case-study aims to understand whether the engagement of individuals with dementia and Huntington's disease (HD) at an early stage is a useful approach to inform the initial development of meaningful digital activities and ultimately its potential introduction into clinical practice.Design/methodology/approachFive patients with dementia and HD at different stages of progression were recruited from an inpatient secure psychiatric hospital. Engagement, usability and preliminary benefits were assessed using a mixed-methods approach through observations, open-ended questions and subjective ratings.FindingsThe content of the tool triggered reminiscence, discussion and positive behavioural and emotional responses. The participants were confident using the tablet but needed support interacting with the touchscreen and, at times, to encourage communication. “Music” and “Videos”, were particularly successful in engaging most participants despite their cognitive and physical difficulties.Originality/valueThis case-study shows that co-production in clinical practice can be successfully implemented to develop activities that meet the interests and needs of patients with dementia and Huntington's disease. The varied and flexible assessment provided rich feedback that will be used to improve the device. This highlights avenues of focus for the development of future pools of activities.
The relationship between morphology and flight in Drosophila: a study of two pairs of sibling species from a natural population
Authors: Flaibani Nicolás , Ortiz Victoria Estefanía , Fanara Juan José , Carreira Valeria Paula 
Published: September 2023

AbstractInsect flight is a complex trait involved in different behaviors, from the search for sexual partners, food, or breeding sites. Many studies have postulated the adaptive advantages of certain morphological traits in relation to increased flight capacity, such as low values of wing loading or high values of wing:thorax ratio and wing–aspect ratio. However, few studies have evaluated the relationship between variables related to flight and morphological traits in Drosophila. This work aimed to study morphological traits in males and females of two pairs of sibling species: Drosophila buzzatii Patterson and Wheeler‐Drosophila koeferae Fontdevila and Wasserman, and Drosophila melanogaster Meigen‐Drosophila simulans Sturtevant, and to analyze its relationship with flight. We detected the highest proportion of flight time in D. koepferae and D. simulans compared to D. buzzatii and D. melanogaster, respectively. Our results also revealed sexual dimorphism, with males exhibiting a higher proportion of flight time than females. Surprisingly, we did not find a general pattern to explain the relationship between morphology and the proportion of flight time because associations varied depending upon the analyses (considering all groups together or each sex‐species combination separately). Moreover, these associations explained a low percentage of variation, suggesting that other nonmorphological components related to flight, such as physiological variables, should be taken into account. This work allowed us to show the variability and complexity of an aspect of flight, suggesting that the adaptive role of the morphological traits studied might have been overestimated.
Preparing municipal water system planning for a changing climate: Integrating climate‐sensitive demand estimates
Authors: Johnson Ryan C. , Burian Steven J. , Halgren James , Irons Trevor , Baur Emily , Aziz Danyal , Hassan Daniyal , Li Jiada , Kirkham Tracie , Stewart Jessie , Briefer Laura 
Published: September 2023

AbstractSeasonality and a changing climate exert strong influences on supply and demand in the western United States, challenging municipal water system (MWS) management. Although supply and demand exhibit characteristics of nonstationarity, the commonly used econometric‐based models to estimate demands discount the influences of climate variability and trends in seasonal MWS vulnerability assessments. Given the projected impacts of climate change on water resources, we use the documented performance of a real‐world MWS with a calibrated systems model to investigate how demands modeled with and without the influences of climate impact system vulnerability indicators—determined by the exceedance of historical daily mean imported water—for MWS planning guidance. Neglecting climatic influences on MWS demands, the model overestimates the volume of imported water by up to 50% and misclassifies vulnerabilities during supply‐limiting conditions. The climate‐sensitive demand estimates reduced model error (i.e., <3% error) and correctly categorized vulnerabilities. Moreover, the MWS exhibited an average threefold greater sensitivity to percent changes in demand relative to percent changes in supply. The sensitivity to variances in demand emphasizes the need to account for factors influencing supply and demand when investigating the impacts of a changing climate, suggesting future research to examine the coupled influences of modeled supply and demand accuracy on MWS performance.
Final report of TKI discontinuation trial with dasatinib for the second attempt of treatment‐free remission after failing the first attempt with imatinib: Treatment‐free Remission Accomplished by Dasatinib (TRAD) study
Authors: Perusini Maria Agustina , Novitzky‐Basso Igor , Atenafu Eshetu G. , Forrest Donna , Bence‐Bruckler Isabelle , Savoie Lynn , Keating Mary‐Margaret , Busque Lambert , Delage Robert , Xenocostas Anargyros , Liew Elena , Laneuville Pierre , Paulson Kristjan , Stockley Tracy , Lipton Jeffrey H. , Leber Brian , Kim Dennis Dong Hwan 
Published: September 2023

SummaryMultiple studies have reported a significant treatment‐free remission (TFR) rate of 50%–60% in patients with chronic myeloid leukaemia (CML) who discontinue tyrosine kinase inhibitor (TKI) therapy. However, the remaining half of these patients still require re‐initiation of TKI therapy for leukaemia control. It remains unclear if TKI drugs should be switched for re‐therapy in patients who failed the first TFR (TFR1) attempt. Our study attempted to determine whether dasatinib therapy after TFR1 failure post‐imatinib discontinuation could improve the likelihood of TFR2. Of 59 patients who lost molecular response after imatinib discontinuation for TFR1, 55 patients (93.2%) were treated with dasatinib, of whom 49 (89.1%) regained MR4.5 or deeper response, with a median time of 1.85 months to achieve MR4.5. Dasatinib was discontinued in 35 patients for TFR2 attempt, of whom 26 patients (74.28%) lost MMR and 6 (17.14%) MR4. Risk factor analysis for the TFR2 after dasatinib discontinuation suggested three significant factors: (1) doubling time of BCR::ABL1 transcript following TFR1 attempt, (2) rapid regaining of molecular response following dasatinib therapy and (3) undetectable BCR::ABL1 transcript prior to TFR2 attempt. The present study showed that dasatinib does not increase the TFR2 rate in general, but a selected group of patients could benefit from this approach.
Evaluation of fetal cardiac output in preterm premature rupture of membranes
Authors: Ozturk Agaoglu Merve , Turgut Ezgi , Agaoglu Zahid , Tokalioglu Eda Ozden , Kara Ozgur , Tanacan Atakan , Sahin Dilek 
Published: September 2023

AbstractAimWe aimed to investigate fetal cardiac output (CO) in pregnancies with preterm premature rupture of membranes (PPROM) and its relationship with umbilical cord pH.MethodsThis was a prospective study in total 90 pregnancies at 24–37 weeks gestation including 42 pregnancies with PPROM and 48 that healthy controls. Fetal cardiac function including combined, left and right CO z‐scores were compared. The neonates in the PPROM group were separated with umbilical cord pH above and below 7.25, and cardiac output was compared between groups.ResultsIn PPROM group, CCO z‐score, left cardiac output (LCO) z‐score, and right cardiac output (RCO) were significantly lower compared to healthy pregnancies (p = .036, p = .001, p = .032, respectively), while RCO z‐score showed no significant differences between the two groups. The aortic annulus and pulmonary artery annulus z‐scores were measured smaller in the PPROM group (p = .000 and p = .001, respectively). In PPROM group, the fetal LCO z‐score was significantly lower in neonates with an umbilical cord pH of 7.25 or less (p = .048).ConclusionThis study provides evidence that fetal CCO is lower in PPROM compared with healthy pregnancies. Reduced LCO z‐scores may be useful for predicting adverse neonatal outcomes in pregnancies with PPROM.
Microbial diversity and authigenic siderite mediation in sediments surrounding the Kedr‐1 mud volcano, Lake Baikal
Authors: Lomakina Anna V. , Bukin Sergei V. , Pogodaeva Tatyana V. , Turchyn Alexandra V. , Khlystov Oleg M. , Khabuev Andrey V. , Ivanov Vyacheslav G. , Krylov Aleksey A. , Zemskaya Tamara I. 
Published: September 2023

AbstractThe gas hydrate‐bearing structure—mud volcano Kedr‐1 (Lake Baikal, southern basin)—is located near the coal‐bearing sediments of the Tankhoy formation of Oligocene–Miocene age and can be an ideal source of gas‐saturated fluid. A significant amount of siderite minerals (FeCO3) were collected from sediments at depths ranging from 0.5 to 327 cm below the lake floor (cmblf). An important feature of these carbonate minerals is the extremely strong enrichment in the heavy 13C isotope, reaching values of +33.3‰ VPDB. The δ13C of the siderite minerals, as well as their morphology and elemental composition, and the δ13CDIC of the co‐existing pore water, differed across layers of the core, which implies at least two generations of siderite formation. Here, we leverage mineralogical and geochemical data with 16S rRNA data from the microbial communities in sediments surrounding layers containing siderite minerals. Statistical data reveal the formation of three clusters of microbial communities based on taxonomical composition, key taxa among bacteria and archaea, and environmental parameters. Diversity and richness estimators decrease with sediment depth, with several similar prevailing clades located at the bottom of the core. Most of the taxa in the deep sediments could be associated with putative metabolisms involving organotrophic fermentation (Bathyarchaeia, Caldatribacteriota, and Chloroflexota). Various groups of methanogens (Methanoregulaceae, Methanosaetaceae, and Methanomassiliicoccales) and methanotrophic (Methanoperedenaceae) archaea are present in the sediment at variable relative abundances throughout the sampled depth. Based on the physicochemical characteristics of the sediment, carbon isotope analysis of carbonate minerals and DIC, and phylogenetic analysis of individual taxa and their metabolic potential, we present several models for subsurface siderite precipitation in Lake Baikal sediments.
Research trends on the relationship between Helicobacter pylori and microbiota: A bibliometric analysis
Authors: Li Yu , Ouyang Yaobin , He Cong 
Published: September 2023

AbstractBackgroundIncreasing evidence has indicated that Helicobacter pylori infection is associated with the complex microbiota in the digestive tract of the human body. We aimed to assess the research trends and hotspots in the field of H. pylori and microbiota using a quantitative method.Materials and MethodsThe clinical studies on H. pylori and microbiota published from 2001 to 2022 were extracted from the Web of Science database. We visualized and analyzed countries/regions, institutions, authors, journals, and keywords through VOSviewer and CiteSpace software. The test techniques, specimen type, as well as microbiota variation after H. pylori infection and eradication were also evaluated.ResultsA total of 98 publications were finally identified, and the number of annual papers increased gradually. China showed its dominant position in the publication outputs, and Nanchang University was the most productive institution. Cong He, Xu Shu, and Yin Zhu published the highest number of papers, whereas Helicobacter was the most productive journal. “Helicobacter pylori” ranked highest in the keyword occurrences. 16S rRNA gene sequencing was the most frequently used method for microbiota analysis. Fecal samples had the highest frequency of use, followed by gastric mucosa and saliva. H. pylori infection was associated with the alterations of microbiota through the digestive tract, characterized by the enrichment of Helicobacter in the stomach. Triple and quadruple therapy were the most utilized eradication regimens, and probiotics supplementation therapy has been proven to reduce side effects and restore microbial diversity.ConclusionsThis bibliometric analysis provides an overview of advancements in the field of H. pylori and microbiota. While numerous studies have been conducted on the correlation between H. pylori and the alterations of microbiota, future research is warranted to investigate the mechanisms underlying the interplay between H. pylori and other microbes in the development of related diseases.
Properties and microstructure of Cf/HfC‐SiC composite prepared by combined process
Authors: Yan Chunlei , Ye Linsen , Chen Liyun , Zhao Zhenguo , Liu Rongjun 
Published: September 2023

AbstractThe Cf/HfC‐SiC composite was produced by precursor infiltration and pyrolysis combined with gaseous silicon infiltration and an open porosity as low as 5.4% was achieved. Cf/HfC‐SiC composite has a thermal conductivity of 21.4 W·m−1·K−1, in addition, its flexural strength, elastic modulus, and fracture toughness are 328.9 ± 58.4 MPa, 48.9 ± 2.8 GPa, and 10.2 ± 1.2 MPa·m1/2, respectively. The compact matrix and the toughing mechanism by fibers account for the good mechanical properties. The Cf/HfC‐SiC composite survives the oxyacetylene torch test and the formation of a protective oxide scale by joint action of SiO2 and HfO2 contributes to good ablation performance of the composite.
Impact of sintering thermal history on MgO‐doped alumina: Reduction of grain growth constant through high heating rates
Authors: Kermani Milad , Wu Jinghua , Liu Zexiao , Zuo Fei , Lin Hua‐Tay , Hu Chunfeng , Grasso Salvatore 
Published: September 2023

AbstractThis work examines the impact of sintering thermal history on kinetics of grain growth for 1264 ppm (0.1 wt%) MgO‐doped alumina. Results suggest that sintering with a high heating rate in the order of ∼103°C min−1 retards grain growth rate. By contrast, a slow heating rate of 5°C min−1 resulted in an increase in grain growth constant by a factor of ∼4. The segregation of Mg to grain boundaries, favored by short sintering duration, is considered to be one of the possible factors contributing to the retarded grain growth rate for the rapidly heated compacts. Furthermore, it is proposed that the simultaneous combination of retarded grain boundary migration rate and limited surface‐diffusion‐driven grain coarsening, promoted by rapid heating, enables pressure‐less fabrication of translucent alumina without a need for vacuum or hydrogen atmosphere. In fact, it is demonstrated that weakly translucent alumina can be produced at relatively low temperatures of 1475–1550°C by sintering with a high heating rate (herein, ∼103°C min−1) in ambient atmosphere.
Trophic interactions and the diet composition of sympatric finfish predators in the tropical demersal ecosystem in the Bay of Bengal
Authors: Ghosh Shubhadeep , Muktha Menon , Satishkumar Mamidi , Ranjan Behera Pralaya , Indira Divipala , Prathibha Rohit , Zacharia Pariyappanal Ulahannan , Gopalakrishnan Achamveetil 
Published: September 2023

AbstractThe dietary composition, foraging strategies, and interspecific trophic interactions were identified for four major demersal carnivorous finfishes, namely, croaker Otolithes ruber, hairtail Trichiurus lepturus, threadfin bream Nemipterus japonicus, and lizardfish Saurida undosquamis, along the north‐western part of Bay of Bengal from 2014 to 2016. Two species, Trichiurus lepturus and Saurida undosquamis, were identified as finfish feeders due to the high number of teleost (clupeids and engraulids) prey. One species, Nemipterus japonicus, had a significantly different diet of metapenaeids and charybdids, and was identified as a shellfish feeder. The final species, Otolithes ruber, preyed equally on crustaceans and teleosts, and was identified as a shellfish‐finfish feeder. The feeding activity of all four species was lower during peak spawning periods and tended to increase with maturity. Feeding preferences varied with seasons. The trophic level ranged from 3.49 to 4.01, classifying the four species as medium‐carnivores or meso‐predators. Niche breadth ranged from 0.170 to 0.421, with seasonal and ontogenetic variations. Individual or subgroup specialization was observed on dominant prey, but intraspecific diet variations indicated all four species to be opportunistic predators. There was substantial prey overlap for Saurida undosquamis with Otolithes ruber and Trichiurus lepturus, which increased ontogenetically and coincided with their peak spawning. Sharing of abundant prey resources together with temporal and ontogenetic resource partitioning at intra‐ and interspecific levels possibly lowered dietary competition, thereby facilitating the coexistence of these demersal predators. This study provides new information on feeding interactions from a tropical demersal ecosystem that can be applied for the ecosystem‐based management of trawl fisheries.
Recidivism in a juvenile court‐sponsored delinquency prevention program
Authors: Windell James O. , Axelrod Bradley N. 
Published: September 2023

AbstractPrevious research on the rates of juvenile re‐offending have been found to be as high as 66% when measuring recidivism by rearrest and as high as 33% when measuring re‐offending by reconvictions within one to three years of release. However, accurately estimating a national juvenile recidivism rate is problematic. This is even more complicated when attempting to determine recidivism for delinquency prevention programs. One of the oldest, and perhaps most successful of these programs, is the Oakland County (Michigan) Youth Assistance Program (OCYA), which began in 1953. The present paper is an attempt to quantify the recidivism rate for youngsters referred to OCYA in a different sample. This study drew on the entire OCYA database from 2004 to 2014 with a random sample of 1540 cases selected. Demographic information of the selected youths, their number of caseworker contacts, the type of offense, and their recidivism record were evaluated using SPSS statistical software. Results showed a relatively low recidivism rate, but participation in OCYA face‐to‐face caseworker contacts or auxiliary programs had no predictive value in forecasting recidivism.
Subclinical diabetes confirmed by 75‐g OGTT influence on the prognosis of decompensated cirrhosis
Authors: Kang Seong Hee , Kim Moon Young , Han Seul Ki , Baik Soon Koo 
Published: September 2023

AbstractBackground and aimDisorders of glucose metabolism, such as impaired glucose tolerance (IGT) and diabetes mellitus (DM), frequently occur in cirrhosis. We aimed to evaluate who needs to be undertaken a 75‐g oral glucose tolerance test (OGTT) to find underlying subclinical diabetes.MethodsThis prospective study included 713 patients with either compensated (Child–Turcotte–Pugh [CTP] class A) or decompensated cirrhosis (CTP class B/C) without previous DM history. All patients underwent a 75‐g OGTT. The patients were divided into three groups: normal glucose tolerance (NGT), IGT, and newly diagnosed DM (subclinical DM).ResultsAmong 713 patients, NGT was diagnosed in 139 (19.5%), IGT in 252 (35.3%), and subclinical DM in 322 (45.2%) patients, respectively. During a median follow‐up period of 42.0 months, the cumulative survival rates of patients were as follows: NGT, 75.6%; IGT, 57.6%; and subclinical DM, 54.8%. Overall, IGT (adjusted hazard ratio [aHR], 1.605; 95% confidence interval [CI] = 1.009–2.553; P = 0.046) and subclinical DM (aHR, 1.840; 95% CI = 1.183–2.861; P = 0.001) were identified as independent predictors of mortality. In patients with compensated cirrhosis (n = 415), neither IGT nor subclinical DM conferred a higher mortality risk. However, among patients with decompensated cirrhosis (n = 298), those with IGT (aHR, 2.394; P = 0.015) and subclinical DM (aHR, 2.211; P = 0.022) showed a survival rate worse than those with NGT. In addition, subclinical DM was identified as an independent risk factor for infection (aHR, 2.508; P = 0.007).ConclusionsIGT and subclinical diabetes by OGTT are associated with an unfavorable prognosis in cirrhosis, and the effect is pronounced in the decompensated state.ClinicalTrials.gov, Number NCT04828512 (https://clinicaltrials.gov/ct2/show/NCT04828512).