bluuebunny/crossref_metadata_2025_split huggingface dataset:
Umbrella systematic review of potential quality indicators for the detection of dysplasia and cancer at upper gastrointestinal endoscopy
Authors: Kamran Umair , Abbasi Abdullah , Umar Nosheen , Tahir Imran , Brookes Matthew J , Rutter Matt , McCord Mimi , Adderley Nicola J , Dretzke Janine , Trudgill Nigel 
Published: September 2023

Abstract
Background and study aims Upper gastrointestinal (UGI) endoscopy lacks established quality indicators. We conducted an umbrella systematic review of potential quality indicators for the detection of UGI cancer and dysplasia.
Methods Bibliographic databases were searched up to December 2021 for systematic reviews and primary studies. Studies reporting diagnostic accuracy, detection rates or the association of endoscopy or endoscopist-related factors with UGI cancer or dysplasia detection were included. AMSTAR2 and JBI checklists were used to assess systematic review and primary study quality. Clinical heterogeneity precluded meta-analysis and findings are summarized narratively.
Results Eight systematic reviews and nine primary studies were included. Image enhancement, especially narrow band imaging, had high diagnostic accuracy for dysplasia and early gastric cancer (pooled sensitivity 0.87 (95% CI 0.84–0.89) and specificity 0.97 (0.97–0.98)). Higher detection rates with longer endoscopy examination times were reported in three studies, but no difference was observed in one study. Endoscopist biopsy rate was associated with increased gastric cancer detection (odds ratio 2.5; 95% confidence interval [CI] 2.1–2.9). Early esophageal cancer (0.17% vs 0.14%, P=0.04) and gastric cancer (0.16% vs 0.12%, P=0.02) detection rates were higher with propofol sedation compared to no sedation. Endoscopies performed by trained endoscopists on dedicated Barrett’s surveillance lists had higher detection rates (8% vs 3%, P<0.001). The neoplasia detection rate during diagnostic endoscopies for Barrett’s esophagus was 7% (95% CI 4%-10%).
Conclusions Image enhancement use, longer examination times, biopsy rate and propofol sedation are potential quality indicators for UGI endoscopy. Neoplasia detection rate and dedicated endoscopy lists are additional potential quality indicators for Barrett’s esophagus
The Impact of Parkinson's Disease on Social Communication: An Exploratory Questionnaire Study
Authors: Sharma Saryu , Fleck Kimberly , Winslow Sherri , Rothermich Kathrin 
Published: September 2023

AbstractIndividuals with Parkinson's disease (PD) often show breakdown in the production and interpretation of aspects of social communication. However, there is no current method of assessment for evaluating social communication dysfunction in individuals with PD. The aim of this study was to develop a self-report questionnaire for individuals with PD to identify their social communication skills, and further recognize the impact of PD on social communication. Fifty-one individuals with Parkinson's disease answered 28 survey questions. These questions pertained to emotional expression and perception, social communication, sarcasm/humor, and pragmatic skills. Exploratory factor analysis and reliability analysis were conducted to identify items loading onto the factors and to check the internal consistency of the items. Individuals with PD reported changes in emotional expression and perception, social communication, sarcasm and humor, and pragmatic skill domains post-PD diagnosis. No correlations were found between age or time since diagnosis and emotional expression, social communication, sarcasm, and humor. This study provides self-reported evidence that individuals with PD experience social communication challenges. Future research should further quantify these challenges, study their impact on daily communicative functioning, and use the results to develop social communication interventions that improve the quality of life for persons with PD.
Inferiorly Based Fasciocutaneous Flaps In Leg - Our Experience
Authors: Jena Dr. Subrat Kumar , Ray Dr. Falguni , Nayak Dr. Mrs. Bijaylakhmi , Das Dr. Binay Kumar 
Published: September 2023

SummaryInferiorly based fasciocutaneous flaps have emerged as an ideal material for the defects in lower leg and foot. We have used this flap in eleven patients since 1986 through 1989. The flaps have proved to be reliable over difficult areas of ankle and foot, either multistaged distant flaps or free flaps are the other alternative. Here inferiorly based fasciocutaneous flaps offer a much simpler and safer answer.
Extensor Digitorum Brevis Manus Muscle - A Diagnostic Red Herring
Authors: Tewari Vinay K , Tandon Pradeep 
Published: September 2023

SummaryExtensor digitorum brevis muscle is an atavistic muscle occurring rarely in the dorsum of hand. The anomaly is so rare that it is usually diagnosed as a ganglion. In the case presented one hand was explored and the presence of the muscle on the other side was confirmed by electromyography.
A Comparative Study of Some Treatment Modalities in Cutaneous Haemangiomas
Authors: Jain P , Sinha J K 
Published: September 2023

Summary151 children with cutaneous haemangiomas were treated using different treatment modalities and the results were compared. Intralesional triamcinolone was found to be the safest and most effective in strawberry lesions. Cavernous lesions in our study responded best to 50% dextrose injections. A combined approach of oral prednisolone and triamcinolone injections was found to be very useful for mixed lesions.
Pectoralis Major Flap In 77 Head And Neck Reconstructions
Authors: Khazanchi Dr. R.K. , Shukla Dr. N.K. , Nanda Dr. R. 
Published: September 2023

Abstract77 patients with head and neck excisional defect are treated by use of Pectoralis major myo cu-taneous, myocutaneous with skin paddle, and composite, incorporating rib. Results are presented.
Intruder-free cumulant-truncated driven similarity renormalization group second-order multireference perturbation theory
Authors: Li Shuhang , Misiewicz Jonathon P. , Evangelista Francesco A. 
Published: September 2023

Accurate multireference electronic structure calculations are important for constructing potential energy surfaces. Still, even in the case of low-scaling methods, their routine use is limited by the steep growth of the computational and storage costs as the active space grows. This is primarily due to the occurrence of three- and higher-body density matrices or, equivalently, their cumulants. This work examines the effect of various cumulant truncation schemes on the accuracy of the driven similarity renormalization group second-order multireference perturbation theory. We test four different levels of three-body reduced density cumulant truncations that set different classes of cumulant elements to zero. Our test cases include the singlet–triplet gap of CH2, the potential energy curves of the XΣg+1 and AΣu+3 states of N2, and the singlet–triplet splittings of oligoacenes. Our results show that both relative and absolute errors introduced by these cumulant truncations can be as small as 0.5 kcal mol−1 or less. At the same time, the amount of memory required is reduced from O(NA6) to O(NA5), where NA is the number of active orbitals. No additional regularization is needed to prevent the intruder state problem in the cumulant-truncated second-order driven similarity renormalization group multireference perturbation theory methods.
ZnO/ZnS core–shell quantum dots with enhanced ultraviolet fluorescence and low cytotoxicity for cell imaging
Authors: Chen Yuhang , Xue Qi , Luo Weiguo , Sun Yu , Li Ming , Hang Tao 
Published: September 2023

Abstract
Zinc oxide quantum dots (ZnO QDs) have gained wide attention due to their wide excitation spectrum, large Stokes shift, adjustable photoluminescence (PL) spectrum, and excellent biocompatibility. However, low fluorescence intensity and poor stability restrict their further applications. In this work, zinc sulfide (ZnS) as a surface modifier, ZnO/ZnS core–shell QDs with type-I core–shell structure and particle size of 5 nm were prepared via sol–gel method. Transmission electron microscope characterization demonstrates the core–shell structure and spherical morphology of the as-synthesized ZnO/ZnS QDs. The PL spectra show that ultraviolet fluorescence has been greatly enhanced. The maximum fluorescence intensity of ZnO/ZnS core–shell QDs increases by 5288.6% compared with that of bare ZnO QDs. The PL quantum yield increases from 9.53% to 30.95%. After being stored for three weeks, the fluorescence performance can be well retained. Furthermore, the cytotoxicity tests confirm the excellent biocompatibility of ZnO/ZnS core–shell QDs, demonstrating they are good candidates for cell imaging.
FSE-Net: feature selection and enhancement network for mammogram classification
Authors: Liao Caiqing , Wen Xin , Qi Shuman , Liu Yanan , Cao Rui 
Published: September 2023

Abstract

Objective. Early detection and diagnosis allow for intervention and treatment at an early stage of breast cancer. Despite recent advances in computer aided diagnosis systems based on convolutional neural networks for breast cancer diagnosis, improving the classification performance of mammograms remains a challenge due to the various sizes of breast lesions and difficult extraction of small lesion features. To obtain more accurate classification results, many studies choose to directly classify region of interest (ROI) annotations, but labeling ROIs is labor intensive. The purpose of this research is to design a novel network to automatically classify mammogram image as cancer and no cancer, aiming to mitigate or address the above challenges and help radiologists perform mammogram diagnosis more accurately. Approach. We propose a novel feature selection and enhancement network (FSE-Net) to fully exploit the features of mammogram images, which requires only mammogram images and image-level labels without any bounding boxes or masks. Specifically, to obtain more contextual information, an effective feature selection module is proposed to adaptively select the receptive fields and fuse features from receptive fields of different scales. Moreover, a feature enhancement module is designed to explore the correlation between feature maps of different resolutions and to enhance the representation capacity of low-resolution feature maps with high-resolution feature maps. Main results. The performance of the proposed network has been evaluated on the CBIS-DDSM dataset and INbreast dataset. It achieves an accuracy of 0.806 with an AUC of 0.866 on the CBIS-DDSM dataset and an accuracy of 0.956 with an AUC of 0.974 on the INbreast dataset. Significance. Through extensive experiments and saliency map visualization analysis, the proposed network achieves the satisfactory performance in the mammogram classification task, and can roughly locate suspicious regions to assist in the final prediction of the entire images.
Flexible capacitive and piezoresistive pressure sensors based on screen-printed parylene C/polyurethane composites in low-pressure range
Authors: Kurnaz Sedat , Ozturk Ozgür , Mehmet Ali Hazar , Guduloglu Utku , Yilmaz Nurdane , Cicek Osman 
Published: September 2023

Abstract
The use of polymers to fabricate flexible pressure sensors as an alternative to conventional pressure sensors has led to the development of physiological monitoring of human body and the electronic skin. In particular, the fabrication of flexible capacitive and piezoresistive sensors using a variety of materials and the investigation of their electromechanical properties are further developments in these fields. Herein, parylene C is synthesized via chemical vapor deposition method. Pressure-sensitive inks are prepared with a composite of parylene C, polyurethane, polymethylmethacrylate, and activated carbon at certain weight ratios. Flexible capacitive and piezoresistive pressure sensors are fabricated by the screen printing method. The sensitivity, detection limit, linearity range, and response/relaxation time, which define the capacitive and piezoresistive properties are investigated and presented in this paper. The sensitivities of the flexible capacitive and piezoresistive pressure sensors are 0.124 kPa−1 and 0.074 kPa−1 in the pressure range of 0.07–1.39 kPa. This study enables parylene C to be used in the composite structure and shows that it can be used not only as a protective layer but also in flexible pressure sensor applications. It also ensures that the design of the flexible capacitance pressure sensor can measure low pressure with high sensitivity compared to the flexible piezoresistive pressure sensor.
Cap-DiBiL: an automated model for crop water requirement prediction and suitable crop recommendation in agriculture
Authors: Munaganuri Ravi Kumar , Rao Yamarthi Narasimha 
Published: September 2023

Abstract
In this technological era, several approaches used to provide the information about suitable crop recommendation means which is crop is suitable for soil. Some of approaches depends on the IoT smart agricultural-devices to gather information from surrounding area. However, several collection of data are used to predict the crops details but it not efficient to provide better performance. Therefore, the proposed model uses various techniques to improve the performance efficiently. Some steps involved in the proposed model as data pre-processing, feature extraction, feature selection, water requirement prediction and recommendation. Initially, the collected IoT data from dataset are pre-processed using data normalization, missing value imputation and one-hot encoding. Then, extract the features from pre-processed data using Gated Residual autoencoder (GRA) model, whereas optimal features are selected using Chaotic Northern Goshawk Optimization (ChaNgo) algorithm. Based on the farmland details, the crop water requirement prediction and suitable crop recommendation due to the market price are carried out using a novel hybrid deep learning model called Channel capsule-assisted stacked dilated Bi-LSTM (Cap-DiBiL). The channel capsule network predicts the crop water requirement and stacked dilated Bi-LSTM is used for suitable crop recommendations such as millets, rice and other crops. Then the proposed model analyses the performance and compares it with several existing techniques to prove the proposed model’s enhancement. The proposed model improved the accuracy as 98.18% for predicting the crop water requirement and crop recommendation. The performance of proposed model for Precision, Recall and F1 score also enhanced as 98.31%, 98.18% and 98.20%.
Outcomes of patients with atrial fibrillation on oral anticoagulation with and without heart failure: the ETNA-AF-Europe registry
Authors: Schnabel Renate B , Ameri Pietro , Siller-Matula Jolanta M , Diemberger Igor , Gwechenberger Marianne , Pecen Ladislav , Manu Marius Constantin , Souza José , De Caterina Raffaele , Kirchhof Paulus 
Published: September 2023

Abstract

Aims
Heart failure (HF) is a risk factor for major adverse events in atrial fibrillation (AF). Whether this risk persists on non-vitamin K antagonist oral anticoagulants (NOACs) and varies according to left ventricular ejection fraction (LVEF) is debated.

Methods and results
We investigated the relation of HF in the ETNA-AF-Europe registry, a prospective, multicentre, observational study with an overall 4-year follow-up of edoxaban-treated AF patients. We report 2-year follow-up for ischaemic stroke/transient ischaemic attack (TIA)/systemic embolic events (SEE), major bleeding, and mortality. Of the 13 133 patients, 1854 (14.1%) had HF. Left ventricular ejection fraction was available for 82.4% of HF patients and was &lt;40% in 671 (43.9%) and ≥40% in 857 (56.1%). Patients with HF were older, more often men, and had more comorbidities. Annualized event rates (AnERs) of any stroke/SEE were 0.86%/year and 0.67%/year in patients with and without HF. Compared with patients without HF, those with HF also had higher AnERs for major bleeding (1.73%/year vs. 0.86%/year) and all-cause death (8.30%/year vs. 3.17%/year). Multivariate Cox proportional models confirmed HF as a significant predictor of major bleeding [hazard ratio (HR) 1.65, 95% confidence interval (CI): 1.20–2.26] and all-cause death [HF with LVEF &lt;40% (HR 2.42, 95% CI: 1.95–3.00) and HF with LVEF ≥40% (HR 1.80, 95% CI: 1.45–2.23)] but not of ischaemic stroke/TIA/SEE.

Conclusion
Anticoagulated patients with HF at baseline featured higher rates of major bleeding and all-cause death, requiring optimized management and novel preventive strategies. NOAC treatment was similarly effective in reducing risk of ischaemic events in patients with or without concomitant HF.
Jumping to new hosts: the diversification of flea beetles (Coleoptera: Chrysomelidae: Alticini) in the context of their host plant associations
Authors: Letsch Harald , Beran Franziska 
Published: September 2023

Abstract
Flea beetles (Alticini) represent one of the most diverse groups within the family Chrysomelidae and are associated with more than 100 different plant families. Conspicuously, only 10 genera account for about a quarter of flea beetle diversity, whereas about 380 genera each comprise less than 10 species, indicating different rates of diversification within the Alticini. Here, we reconstructed the phylogenetic relationships of 608 species in 101 Alticini genera using mitogenomes and cytochrome oxidase I, and applied several frameworks of clade-specific diversification rate analyses. Increased diversification rates were consistently detected in the cosmopolitan genera Altica Goffroy, Longitarsus Berthold, and Phyllotreta Chevrolat, and in neotropical taxa of the subtribe Oedionychina. In addition, we tested whether the evolution of specialized interactions with plants of the order Brassicales influenced the diversification of Phyllotreta and Psylliodes Berthold flea beetles. Specialization on Brassicales was only associated with increased diversification rates in Phyllotreta but not in Psylliodes. Our results indicate that host associations per se do not explain different diversification rates and lay the groundwork for investigating the evolutionary drivers of rapid radiations in Alticini.
Combining antimicrobial substances for Campylobacter post harvest mitigation on chicken breast fillet and chicken skin — any synergistic effects?
Authors: Bogun Katrin , Peh Elisa , Siekmann Lisa , Plötz Madeleine , Kittler Sophie 
Published: September 2023

Abstract

Aims
To reduce Campylobacter along the food chain, we investigated the mitigation potential of four antimicrobial compounds against Campylobacter using a new evaluation scheme.

Methods and Results
Using the checkerboard method, the minimum inhibitory concentration (MIC) values of two organic acids (peroxyacetic acid and lactic acid) and two plant extracts (carvacrol and resveratrol) against a C. jejuni and a C. coli field isolate were determined as well as the fractional inhibitory concentration (FIC) indices of combined treatment. The lowest MIC values were found for peroxyacetic acid (0.03 mg mL−1) and carvacrol (0.06 mg mL−1). Based on subsequent sensory studies, peroxyacetic acid and carvacrol were selected for challenge tests to quantitatively determine the reducing potential against Campylobacter on chicken meat and chicken skin. Applying peroxyacetic acid significantly reduced Campylobacter counts on chicken skin with maximum reductions of 3.3 log-units (P &lt; .0001), while the combination of peroxyacetic acid and carvacrol resulted in significant reductions of only 0.4 log-units on chicken breast fillet 24 hours after treatment but not thereafter (P = .0192).

Conclusions
Peroxyacetic acid is suitable as a postharvest intervention measure to reduce Campylobacter concentration on chicken skin without reducing consumer acceptance.
PSXIII-17 Effects of dietary forage inclusion during finishing on growth performance, feeding behavior, and ruminal fermentation in steers at risk for acidosis
Authors: Dornbach Colten W , McCann Joshua C 
Published: September 2023

Abstract
The objective was to evaluate the effects of dietary forage inclusion during finishing on growth performance, feeding behavior, and ruminal fermentation in steers at risk for acidosis. Angus × Simmental steers (n = 240; body weight = 350 ± 58 kg) were blocked by body weight and allotted into 18 pens. Feeding behavior was collected and analyzed from the initial 45 d steers were fed a high-moisture corn-based finishing ration in GrowSafe bunks to determine steers (20%) at greatest risk for developing acidosis. The at-risk steers (n = 48) were utilized in a randomized complete block design. Steers were stratified by initial body weight within block and assigned to 8 pens of 6 steers. Pens were randomly assigned to 1 of 2 dietary treatments: (1) 15% (15CS) or (2) 30% corn silage (30CS) on a dry matter basis where corn silage replaced high moisture corn in the finishing diet. Overall body weight, average daily gain, dry matter intake, and gain:feed were not affected (P ≥ 0.19) by treatment. Carcass characteristics were not affected by treatment (P ≥ 0.39). Steers consuming 30CS had greater (P ≤ 0.05) meal frequency and eating rate, as well as decreased meal length, from d 0 to 112. Fluctuations in dry matter intake during the final 56 d of finishing were not affected by treatment (P ≥ 0.20). Ruminal pH was collected prior to feeding and tended to exhibit a treatment × day effect (P = 0.05) with 30CS steers having increased ruminal pH on d 56 and 112. No treatment × day effect was observed for molar proportions of acetate, propionate, and butyrate (P ≥ 0.11) in ruminal fluid. Overall, increasing dietary forage during finishing altered feeding behaviors and ruminal fermentation in steers at risk for acidosis, but did not affect growth performance.
Prolactin promotes crop epithelial proliferation of domestic pigeons (Columba livia) through the Hippo signaling pathway
Authors: Zhu Jianguo , Teng Xingyi , Wang Liuxiong , Zheng Mingde , Meng Yu , Liu Tingwu , Liu Ying , Huan Haixia , Gong Daoqing , Xie Peng 
Published: September 2023

Abstract
The purpose of this study was to investigate whether prolactin (PRL) regulates the proliferation of pigeon crop epithelium through the Hippo signaling pathway during the breeding cycle. Twenty-four pairs of adult pigeons were allotted to four groups by different breeding stages, and their crops and serum were sampled. Eighteen pairs of young pigeons were selected and divided into three groups for the injection experiments. The results showed that the serum PRL content and crop epithelial thickness of pigeons increased significantly at day 17 of incubation (I17) and day 1 of chick-rearing (R1). In males, the mRNA levels of yes-associated transcriptional regulator (YAP) and snail family transcriptional repressor 2 (SNAI2) were peaked at I17, and the gene levels of large tumor suppressor kinase 1 (LATS1), serine/threonine kinase 3 (STK3), TEA domain transcription factor 3 (TEAD3), connective tissue growth factor (CTGF), MYC proto-oncogene (c-Myc) and SRY-box transcription factor 2 (SOX2) reached the maximum value at R1. In females, the gene expression of YAP, STK3, TEAD3, and SOX2 reached the greatest level at I17, the expression profile of SAV1, CTGF, and c-Myc were maximized at R1. In males, the protein levels of LATS1 and YAP were maximized at R1 and the CTGF expression was upregulated at I17. In females, LATS1, YAP, and CTGF reached a maximum value at I17, and the expression level of phosphorylated YAP was minimized at I17 in males and females. Subcutaneous injection of prolactin (injected for 6 d, 10 μg per kg body weight every day) on the left crop of pigeons can promote the proliferation of crop epithelium by increasing the CTGF level and reducing the phosphorylation level of YAP. YAP-TEAD inhibitor verteporfin (injection for 6 d, 2.5 mg per kg body weight every day) can inhibit the proliferation of crop epithelium induced by prolactin by inhibiting YAP and CTGF expression. In conclusion, PRL can participate in crop cell proliferation of pigeons by promoting the expression of YAP and CTGF in Hippo pathway.