bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of Benign Paroxysmal Positional Vertigo with Depression and Anxiety—A Systematic Review and Meta‐Analysis
Authors: Yeo Brian Sheng Yep , Toh Emma Min Shuen , Lim Nicholas E‐Kai , Lee Rachel Siying , Ho Roger Chun Man , Tam Wilson Wai San , Ngo Raymond Yeow Seng 
Published: August 2023

ObjectiveTo evaluate the extent to which Benign Paroxysmal Positional Vertigo (BPPV) is associated with a higher prevalence of depression and anxiety in patients.Data SourcesThree databases including PubMed, Embase, and The Cochrane Library were searched by two independent authors from inception to June 12, 2022 for observational studies and randomized controlled trials investigating the association between BPPV and depression and anxiety. We included studies published as full‐length articles in peer‐reviewed journals with an adult population aged at least 18 years who have BPPV, detected through validated clinical methods like clinical diagnosis, interview and Dix‐Hallpike test.ResultsA total of 23 articles met the final inclusion criteria and 19 articles were included in the meta‐analysis. BPPV was associated with a 3.19 increased risk of anxiety compared to controls, and 27% (17%–39%) of BPPV patients suffered from anxiety. Furthermore, the weighted average Beck's Anxiety Inventory score was 18.38 (12.57; 24.18), while the weighted average State–Trait Anxiety Index score was 43.08 (37.57; 48.60).ConclusionThere appears to be some association between BPPV and anxiety, but further studies are required to confirm these associations. Laryngoscope, 134:526–534, 2024
Kinetic Studies and Temperature‐Induced Morphological Changes of Peptide Decorated Nano‐Objects via Polymerization‐Induced Self‐Assembly
Authors: Benkhaled Belkacem Tarek , Chouirfa Hamza , Vezenkov Lubomir , Gomri Chaimaa , Chaix Arnaud , Subra Gilles , Ladmiral Vincent , Semsarilar Mona 
Published: August 2023

AbstractIn the present work, combining polymerization‐induced self‐assembly (PISA) with self‐assembling peptides (SAPs) peptide−polymer hybrid nanostructures are prepared, harnessing the advantages of PISA and the self‐assembling driving force of SAPs. A tripeptide methacrylamide denoted as MAm‐GFF, where MAm, G, and F stand for methacrylamide, glycine, and phenylalanine, is copolymerized with glycerol monomethacrylate (GMA) by reversible addition−fragmentation chain transfer polymerization (RAFT) in dimethylformamide to produce a P(GMA62‐stat‐(MAm‐GFF)7) macromolecular chain transfer agent (macro‐CTA). This peptide‐containing macro‐CTA is then successfully chain‐extended with poly(2‐hydroxypropyl methacrylate) (PHPMA) by aqueous dispersion PISA, forming P(GMA62‐stat‐(MAm‐GFF)7)‐b‐PHPMA27 self‐assembled objects. The impacts of temperature and monomer conversion on the morphologies formed during the PISA process are investigated by analyzing samples withdrawn at different time during the polymerization of HPMA using transmission electron microscopy (TEM) and dynamic light scattering (DLS) at different temperatures (5–70 °C).
Ultrasonic in situ evaluation of the bolt preload without referencing an unloaded state using a combination of longitudinal and transverse waves
Authors: Niwinski T. J. , Kraemer F. , Klein M. , Oechsner M. , Herter S. , Becker M. M. 
Published: August 2023

AbstractDie ultraschallbasierte Vorspannkraftermittlung an Schrauben wird derzeit überwiegend mit der Ein‐Moden‐Methode realisiert. Diese Methode basiert auf der Laufzeitmessung von Longitudinalwellen. Hierbei ist für jede Schraube eine Referenzmessung im nicht verspannten Zustand notwendig. In der vorliegenden Publikation wird die Ein‐Moden‐Methode um eine weitere Ultraschallwellenart, die Transversalwelle, ergänzt. Es wird dargestellt, dass mit der Zwei‐Moden‐Methode auf eine Referenzmessung im nicht verspannten Zustand verzichtet werden kann. Ein analytisches Verfahren zur Bestimmung des schraubfallspezifischen akusto‐elastischen Materialkennwerts (K‐Wert) wird vorgestellt, welcher für die ultraschallbasierte Vorspannkraftermittlung notwendig ist. Die analytisch ermittelten K‐Werte werden mit experimentellen K‐Werten aus Zugversuchen an Schrauben verglichen. Der Einfluss von Werkstoff, Festigkeitsklasse und Oberflächenschutzsystem wurde an zylindrischen Werkstoffproben ermittelt. In Bauteilversuchen wurden Vorspannkräfte an montierten Schrauben mit der Zwei‐Moden‐Methode ermittelt, ein möglicher Einfluss des Montageverfahrens untersucht und die Ergebnisse hinsichtlich ihrer Genauigkeit interpretiert.
Monocytes in neonatal stroke and hypoxic‐ischemic encephalopathy: Pathophysiological mechanisms and therapeutic possibilities
Authors: Pimentel‐Coelho Pedro M. 
Published: August 2023

AbstractNeonatal arterial ischemic stroke (NAIS) and neonatal hypoxic‐ischemic encephalopathy (HIE) are common causes of neurological impairments in infants, for which treatment options are very limited. NAIS and HIE induce an innate immune response that involves the recruitment of peripheral immune cells, including monocytes, into the brain. Monocytes and monocyte‐derived cells have the potential to contribute to both harmful and beneficial pathophysiological processes, such as neuroinflammation and brain repair, but their roles in NAIS and HIE remain poorly understood. Furthermore, recent evidence indicates that monocyte‐derived macrophages can persist in the brain for several months following NAIS and HIE in mice, with possible long‐lasting consequences that are still unknown. This review provides a comprehensive overview of the mechanisms of monocyte infiltration and their potential functions in the ischemic brain, focusing on HIE and NAIS. Therapeutic strategies targeting monocytes and the possibility of using monocytes for cell‐based therapies are also discussed.
Impact of correlated observation errors on the conditioning of variational data assimilation problems
Authors: Goux Olivier , Gürol Selime , Weaver Anthony T. , Diouane Youssef , Guillet Oliver 
Published: August 2023

SummaryAn important class of nonlinear weighted least‐squares problems arises from the assimilation of observations in atmospheric and ocean models. In variational data assimilation, inverse error covariance matrices define the weighting matrices of the least‐squares problem. For observation errors, a diagonal matrix (i.e., uncorrelated errors) is often assumed for simplicity even when observation errors are suspected to be correlated. While accounting for observation‐error correlations should improve the quality of the solution, it also affects the convergence rate of the minimization algorithms used to iterate to the solution. If the minimization process is stopped before reaching full convergence, which is usually the case in operational applications, the solution may be degraded even if the observation‐error correlations are correctly accounted for. In this article, we explore the influence of the observation‐error correlation matrix () on the convergence rate of a preconditioned conjugate gradient (PCG) algorithm applied to a one‐dimensional variational data assimilation (1D‐Var) problem. We design the idealized 1D‐Var system to include two key features used in more complex systems: we use the background error covariance matrix () as a preconditioner (B‐PCG); and we use a diffusion operator to model spatial correlations in and . Analytical and numerical results with the 1D‐Var system show a strong sensitivity of the convergence rate of B‐PCG to the parameters of the diffusion‐based correlation models. Depending on the parameter choices, correlated observation errors can either speed up or slow down the convergence. In practice, a compromise may be required in the parameter specifications of and between staying close to the best available estimates on the one hand and ensuring an adequate convergence rate of the minimization algorithm on the other.
A coordinate transformation based barycentric interpolation collocation method and its application in bending, free vibration and buckling analysis of irregular Kirchhoff plates
Authors: Huang Z. M. , Peng L. X. 
Published: August 2023

AbstractIn this article, a meshless barycentric interpolation collocation method (BICM) with coordinate transformation is proposed to solve the governing partial differential equations (PDEs) for bending, free vibration and buckling problems of irregular plates. First, the coordinate transformation equations for first to fourth derivatives are introduced. Then the PDEs and boundary conditions defined in a physical domain are transformed into a rectangular domain (reference domain) with the derived differential interpolation matrices. The presented BICM can solve the PDEs based on the reference domain and is adaptive to irregular problem domains. Finally, the bending, free vibration and buckling problems of Kirchhoff plates with irregular shapes are studied with the proposed method. To illustrate the effectiveness of the proposed method, the results are compared with those given by theoretical solutions, finite element methods and literature.
Preventive effect of aripiprazole once monthly on rehospitalization for bipolar disorder: A multicenter 1‐year retrospective mirror image study
Authors: Goto Junichi , Shono Masahiro , Abe Yasuhisa , Fujita Yasutaka , Ueda Keishi , Yoshida Binchi , Nabeshima Yoshihiro 
Published: August 2023

AbstractAimWe conducted a 1‐year retrospective mirror‐image study to investigate the effect of aripiprazole once monthly (AOM) on rehospitalization for bipolar disorder.MethodsParticipants were recruited from psychiatric emergency and acute care hospitals in western Japan. We included 39 participants with bipolar disorder who had been administered AOM for at least 1 year with no missing medical records during the observational period. The primary outcomes were rehospitalization rate, number of rehospitalizations, total hospitalization days, and time to rehospitalization in the context of overall psychiatric readmissions. The significance level was set at p < 0.05.ResultsAOM significantly reduced the rehospitalization rate from 23/39 (59%) to 7/39 (18%) (p = 0.001). The number of rehospitalizations decreased significantly from a mean of 0.85 per person‐year to 0.41 per person‐year (p = 0.048). The total hospitalization days significantly decreased from a mean of 34.9 days to 14.4 days (p = 0.008). AOM significantly prolonged the time to rehospitalization (p < 0.001).ConclusionThis study found that AOM reduces overall psychiatric rehospitalization for bipolar disorder based on data from 1 year before and after AOM administration in the real‐world setting. Future studies should examine the robustness and persistence of the rehospitalization preventive effect of AOM with larger sample sizes and longer observation periods beyond 1 year.
Numerical Fréchet derivatives of the displacement tensor for 2.5‐D frequency‐domain seismic full‐waveform inversion in viscoelastic TTI media
Authors: Yang Qingjie , Zhou Bing , Engsig Marcus , Won Moosoo , Riahi Mohamed Kamel , Al‐khaleel Mohammad , Greenhalgh Stewart 
Published: August 2023

AbstractDerivatives of the displacement tensor with respect to the independent model parameters of the subsurface, also called Fréchet derivatives (or sensitivity kernels), are a key ingredient for seismic full‐waveform inversion (FWI) with a local‐search optimization algorithm. They provide a quantitative measure of the expected changes in the seismograms due to perturbations of the subsurface model parameters for a given survey geometry. Because 2.5‐D wavefield modelling involves a real point source in a 2‐D geological model with 3‐D (spherical) wave properties, it yields synthetic data much closer to the actual practical field data than the commonly used 2‐D wave simulation does, which uses an unrealistic line‐source in which the waves spread cylindrically. Based on our recently developed general 2.5‐D wavefield modelling scheme, we apply the perturbation method to obtain explicit analytic expressions for the derivatives of the displacement tensor for 2.5‐D/2‐D frequency‐domain seismic FWI in general viscoelastic anisotropic media. We then demonstrate the numerical calculations of all these derivatives in two common cases: (1) viscoelastic isotropic; and (2) viscoelastic tilted transversely isotropic (TTI) solids. Examples of the differing sensitivity patterns for the various derivatives are investigated and compared for four different homogeneous models involving 2‐D and 2.5‐D modelling. Moreover, the numerical results are verified against the analytic solutions for homogeneous models. We further validate the numerical derivatives in a 2‐D heterogeneous viscoelastic TTI case by conducting a synthetic data experiment of frequency‐domain FWI to individually recover the 12 independent model parameters (density, dip angle, 5 elastic moduli and 5 corresponding Q‐factors) in a simple model comprising an anomalous square box target embedded in a uniform background. Another 2.5‐D multi‐target model experiment presenting impacts from four common seismic surveying geometries validates the Fréchet derivatives again.
Impact of visceral fat on coronary artery disease as defined by quantitative computed tomography angiography
Authors: Karlsberg Daniel , Steyer Henry , Fisher Rebecca , Crabtree Tami , Min James K. , Earls James P. , Rumberger John 
Published: August 2023

AbstractObjectiveObesity is associated with all‐cause mortality and cardiovascular disease (CVD). Visceral fat (VF) is an important CVD risk metric given its independent correlation with myocardial infarction and stroke. This study aims to clarify the relationship between the presence and severity of VF with the presence and severity of coronary artery plaque.MethodsIn 145 consecutive asymptomatic patients, atherosclerosis imaging‐quantitative computed tomography was performed for total plaque volume (TPV) and percentage atheroma volume, as well as the volume of noncalcified plaque (NCP), calcified plaque, and low‐density NCP (LD‐NCP), diameter stenosis, and vascular remodeling. This study also included VF analysis and subcutaneous fat analysis, recording of outer waist circumference, and percentage body fat analysis.ResultsThe mean age of the patients was 56.1 [SD 8.5] years, and 84.0% were male. Measures of visceral adiposity (mean [SD, Q1–Q3 thresholds]) included estimated body fat, 28.7% (9.0%, 24.1%–33.0%); VF, 169.8 cm2 (92.3, 102.0–219.0 cm2); and subcutaneous fat, 223.6 mm2 (114.2, 142.5–288.0 mm2). The Spearman correlation coefficients of VF and plaque volume included TPV 0.22 (p = 0.0074), calcified plaque 0.12 (p = 0.62), NCP 0.25 (p = 0.0023), and LD‐NCP 0.37 (p < 0.0001). There was a progression of the median coronary plaque volume for each quartile of VF including TPV (Q1: 19.8, Q2: 48.1, Q3: 86.4, and Q4: 136.6 mm3 [p = 0.0098]), NCP (Q1: 15.7, Q2: 35.4, Q3: 86.4, and Q4: 136.6 mm3 [p = 0.0032]), and LD‐NCP (Q1: 0.6, Q2: 0.81, Q3: 2.0, and Q4: 5.0 mm3 [p < 0.0001]).ConclusionsThese findings demonstrate progression with regard to VF and TPV, NCP volume, and LD‐NCP volume. Notably, there was a progression of VF and amount of LD‐NCP, which is known to be high risk for future cardiovascular events. A consistent progression may indicate the future utility of VF in CVD risk stratification.
Stochastic maximum principle for discrete time mean‐field optimal control problems
Authors: Ahmadova Arzu , Mahmudov Nazim I. 
Published: August 2023

AbstractThis article studies optimal control of a discrete‐time stochastic differential equation of mean‐field type with coefficients dependent on function of the law and state of the process. A new version of the maximum principle for discrete‐time mean‐field type stochastic optimal control problems is established, using new discrete‐time mean‐field backward stochastic equations. The cost functional is also of mean‐field type. The study derives necessary first‐order and sufficient optimality conditions using adjoint equations that take the form of discrete‐time backward stochastic differential equations with a mean‐field component. An optimization problem for production and consumption choice is used as an example.
Density functional theory investigation of the energy storage potential ofgraphene‐polypyrrolenanocomposites as high‐performance electrode for Zn‐ion batteries
Authors: Adedoja Oluwaseye Samson , Sadiku Emmanuel Rotimi , Hamam Yskandar 
Published: August 2023

AbstractThe present research explores, through the density functional theory (DFT) calculations, the viability of graphene‐polypyrrole (G/PPy) nanocomposites as an effective material for energy storage in Zn‐ion batteries. To this end, the CASTEP calculator in the Materials Studio software was employed to examine the electronic and structural properties of the nanocomposites and their potential to enhance energy storage capabilities of Zn‐ion batteries. Specifically, the study investigates the interaction of the Zn‐adatom with the nanocomposites, electronic properties, specific capacity, Zn adatom diffusion behavior, structural, and thermal stability, as well as the mechanisms through which the nanocomposites store energy. The results show that the adsorption calculation for PPy onto the graphene nanosheet has an exothermic adsorption energy of −1.68 eV and an adsorption height of 3.28 Å. The loading of Zn atoms onto the Gr/PPy nanocomposite yielded a maximum specific capacity of 510.12 mAh g−1, resulting into a weak adsorption energy of −0.078 eV. The nanocomposite exhibited an extremely low Zn diffusion barrier of 12 meV, enabling a fast Zn diffusion on its surface. These findings suggest that G/PPy nanocomposites hold promise as a material to enhance energy storage in Zn‐ion batteries. The study, through DFT calculations, offers valuable insights into the electronic and structural properties of G/PPy nanocomposites and their potentials for improved energy storage in Zn‐ion batteries. It thus, contributes significantly to the current understanding of energy storage materials and provides a foundation for further research on the development of more effective and efficient energy storage solutions.HighlightsDFT investigations of G/PPy nanocomposites show potential for improved energy storage in Zn‐ions batteries.The electronic and structural properties of the nanocomposites offer valuable insight into their feasibility.The results show that G/PPy nanocomposites can enhance energy storage in Zn‐ion batteries.It contributes to the current understanding of energy storage nanocomposite materials.It provides a framework for developing effective and efficient energy storage technologies.
Outcomes of psychological support skills training for cancer care staff: Skill acquisition, work engagement, mental wellbeing and burnout
Authors: Malins Sam , Boutry Clement , Moghaddam Nima , Rathbone James , Gibbons Felicity , Mays Chloe , Brooks Daniel , Levene Joanna 
Published: August 2023

AbstractObjectivePsychological support skills training has the potential to improve both the ability of cancer staff to help their patients, and staff wellbeing. However, few recent studies have assessed both these outcomes or incorporated current developments in psychological skills training, such as deliberate practice, which includes the use of iterative, corrective feedback to identify and improve individualised skill deficits. No studies have evaluated the contribution that psychological skills training could make to cancer care staff wellbeing and expertise in the wake of the COVID‐19 pandemic. This study aimed to evaluate staff skill acquisition and work‐related wellbeing following psychological support skills training that applied deliberate practice principles.MethodA 2‐day training and monthly supervision was offered to 145 cancer care staff that focused on brief assessment and intervention skills for patients experiencing mental health problems after cancer diagnosis and treatment. Deliberate practice principles were used to focus training on skills practice and feedback, over technique description. Self‐reported ability to perform key skills taught, staff mental wellbeing, work engagement, and burnout were assessed at baseline, 3‐month and 8‐month follow‐up.ResultsSignificant improvements in skills, mental wellbeing, burnout and work engagement were reported at 8‐month follow‐up. Full engagement in both training sessions was predicted by poorer baseline mental wellbeing, more positive evaluation of initial training, supervision attendance, and shorter follow‐up.ConclusionA 2‐day psychological support skills training using deliberate practice principles may support improvement in staff skill, mental wellbeing, burnout and work engagement.
Variants in FGF10 cause early onset of severe childhood interstitial lung disease: A detailed description of four affected children
Authors: Schütz Katharina , Schmidt Axel , Schwerk Nicolaus , Renz Diane Miriam , Gerard Benedicte , Schaefer Elise , Antal Maria Cristina , Peters Sophia , Griese Matthias , Rapp Christina K. , Engels Hartmut , Cremer Kirsten , Bergmann Anke Katharina , Schmidt Gunnar , Auber Bernd , Kamp Jan C. , Laenger Florian , von Hardenberg Sandra 
Published: August 2023

AbstractIntroductionFibroblast growth factor 10 (FGF10) is a signaling molecule with a well‐established role for lung branching morphogenesis. Rare heterozygous, deleterious variants in the FGF10 gene are known causes of the lacrimo‐auriculo‐dento‐digital (LADD) syndrome and aplasia of lacrimal and salivary glands. Previous studies indicate that pathogenic variants in FGF10 can cause childhood Interstitial Lung Disease (chILD) due to severe diffuse developmental disorders of the lung, but detailed reports on clinical presentation and follow‐up of affected children are lacking.MethodsWe describe four children with postnatal onset of chILD and heterozygous variants in FGF10, each detected by exome or whole genome sequencing.ResultsAll children presented with postnatal respiratory failure. Two children died within the first 2 days of life, one patient died at age of 12 years due to right heart failure related to severe pulmonary hypertension (PH) and one patient is alive at age of 6 years, but still symptomatic. Histopathological analysis of lung biopsies from the two children with early postpartum demise revealed diffuse developmental disorder representing acinar dysplasia and interstitial fibrosis. Sequential biopsies of the child with survival until the age of 12 years revealed alveolar simplification and progressive interstitial fibrosis.DiscussionOur report extends the phenotype of FGF10‐related disorders to early onset chILD with progressive interstitial lung fibrosis and PH. Therefore, FGF10‐related disorder should be considered even without previously described syndromic stigmata in children with postnatal respiratory distress, not only when leading to death in the neonatal period but also in case of persistent respiratory complaints and PH.