bluuebunny/crossref_metadata_2025_split huggingface dataset:
An efficient mesh router nodes placement in wireless mesh networks based on moth‐flame optimization algorithm
Authors: Nouri Nabil abdelkader , Aliouat Zibouda , Naouri Abdenacer , Hassak Soufiene ali 
Published: March 2023

SummaryOne of the most challenging tasks is deploying a wireless mesh network backbone to achieve optimum client coverage. Previous research proposed a bi‐objective function and used a hierarchical or aggregate weighted sum method to find the best mesh router placement. In this work, to avoid the fragmented network scenarios generated by previous formulations, we suggest and evaluate a new objective function to maximize client coverage while simultaneously optimizing and maximizing network connectivity for optimal efficiency without requiring knowledge of the aggregation coefficient. In addition, we compare the performance of several recent meta‐heuristic algorithms: Moth‐Flame Optimization (MFO), Marine Predators Algorithm (MPA), Multi‐Verse Optimizer (MVO), Improved Grey Wolf Optimizer (IGWO), Salp Swarm Algorithm (SSA), Grey Wolf Optimizer (GWO), Whale Optimization Algorithm (WOA), Harris Hawks Optimization (HHO), Particle Swarm Optimization (PSO), Sine Cosine Algorithm (SCA), and Slime Mould Algorithm (SMA). We empirically examined the performance of the proposed function using different settings. The results show that our proposed function provides higher client coverage and optimal network connectivity with less computation power. Also, compared to other optimization algorithms, the MFO algorithm gives higher coverage to clients while maintaining a fully connected network.
Life cycle cost‐based optimization framework for seismic design and target safety quantification of dual steel buildings with buckling‐restrained braces
Authors: Ahmadie Amiri Hossein , Estekanchi Homayoon E. 
Published: March 2023

AbstractThis study proposes an efficient risk‐targeted framework for integrated optimal seismic design and quantifying target safety of Special Moment‐Resisting Frames (SMRFs) with Buckling‐Restrained Braces (BRBs) in the typical dual steel buildings. This framework provides an automated design procedure formulated as a constrained single‐objective optimization problem to achieve the minimum Life Cycle Cost (LCC) within the Particle Swarm Optimization (PSO) algorithm and can be the basis of current seismic codes for target safety calibration. LCC includes initial construction cost and lifetime seismic losses such as repair cost, repair time, and casualties. FEMA P‐58 methodology is employed for the LCC analysis of the building under possible earthquakes during its lifetime, which is able to take into account potential uncertainties in the hazard‐response‐damage‐loss relationship. An appropriate cost model is developed to estimate the initial and repair cost of the studied BRBs. Minimum requirements of ASCE and AISC codes are considered as design constraints. Nonlinear response history analysis through the Endurance Time (ET) method is utilized to estimate the structural responses versus seismic intensity. Three 4‐, 8‐, and 12‐story steel buildings with dual seismic force‐resisting system consisting of SMRF and BRB (called steel SMRF‐BRB) are selected as the case study. Each building is optimally designed with two approaches: (1) LCC‐based design within the proposed framework and (2) code‐based design to minimize initial construction cost. Comparison of optimized buildings with the two design approaches in terms of structural responses and seismic consequences demonstrates that fulfilling the minimum code requirements at a given seismic hazard level is not sufficient to minimize lifetime seismic losses of steel SMRF‐BRBs. This is because the optimal designs obtained from the code‐based approach are associated with damage concentration, irreparability, and high collapse probability, especially in seismic events more severe than the design level. The proposed LCC‐based approach provides useful information for improving the lifetime seismic performance of steel SMRF‐BRBs.
Quality of service‐aware adaptive radio resource management based on deep federated Q‐learning for multi‐access edge computing in beyond 5G cloud‐radio access network
Authors: Kumar Naveen , Ahmad Anwar 
Published: March 2023

AbstractDue to the exponential increase of mobile data services, both industry and academia have turned their focus for improving the quality of service (QoS) provisioning for the beyond 5G (B5G) networks. In this paper, an adaptive QoS‐aware resource allocation scheme is developed for multi‐tenant and multi‐service cloud‐radio access networks (C‐RAN) mobile edge computing scenario with the aim of maximizing network performance over time. First, a multi‐user C‐RAN resource allocation architecture for task computation and result collection is developed, where edge nodes can take on user equipments' (UEs) computation‐intensive activities. Then deep reinforced learning (DRL) based multi‐user resource allocation scheme, that is, deep federated Q‐learning (DFQL) is developed for determining the best resource allocation policy. To maximize the validation accuracy of the global model in the FL while satisfying resource restrictions, this technique learns resource allocation immediately in contrast to the present allocation mechanisms. A realistic dataset is built for assessing the proposed method using 5G experimental prototype based on open air interface (OAI). At last, the effectiveness of the proposed scheme is demonstrated, where the performance of the scheme is compared with the existing resource allocation techniques.
Diffusive orthogonal load balancing for Euler–Lagrange simulations
Authors: Stock Antoine , Lartigue Ghislain , Moureau Vincent 
Published: March 2023

AbstractIn the context of unsteady 3D simulations of particle‐laden flows, a new double‐constraint load balancing strategy for Euler–Lagrange models is proposed. The method relies on an existing Eulerian partitioning and implements a Lagrangian load balancing step, which is orthogonal to the pre‐existing Eulerian balancing. This orthogonality property ensures to keep a near‐to‐ideal Eulerian load balance while strongly improving the distribution of the Lagrangian particles on the processors. The method has been designed to handle large unstructured 3D meshes on complex geometries. Lagrangian performance measurements performed on massively parallel simulations of realistic spray cases show a CPU cost reduction up to 70% compared to the unbalanced case.
Studying the prevalence of musculoskeletal pain among a sample of medical students in Damascus, Syria. A cross‐sectional study
Authors: Torbey André , Kadri Saeed A. , Asaad Saja Al , Zahrawi Hanaa , Alhouri Ahmad , Harba Ghaiyath , Torbey Carla , Orfali Tasnim Al , Ahmad Abdalla Mohamad Zaid , Chaar Modar Al , Dammad Seaba Al , Al Dammad Ola Haitham , Zawda Aous , Kudsi Mayssoun 
Published: March 2023

AbstractBackgroundA considerable number of medical students experience musculoskeletal pain (MSP) during their academic years. In this study, we seek to determine the prevalence of MSP, as well as its associated risk factors, among a sample of medical students at two major universities in Damascus, Syria.MethodsA cross‐sectional study was conducted in two universities, with a total of 2009 medical students participating in filling‐in the paper‐based questionnaire. A modified version of the Standardized Nordic Questionnaire was utilized in this study.ResultsThe questionnaire was completed by 2009 medical students. The majority were between the ages of 21 and 25 years old, female (53%), and in their clinical years (55%). 1081 (54%) of all students had at least one MSP site in the previous week, while 1654 (82%) had at least one MSP site in the last year. MSP in the previous week was strongly linked with a history of trauma (odds ratio [OR] 2.26, 95% confidence interval [CI] 1.79–2.86,p = 0.001), as well as a family history of MSP (OR 1.40, 95% CI 1.12–1.76,p = 0.0029). MSP in the previous year was significantly associated with gender (OR 0.637, 95% CI 0.50–0.80,p = 0.0001), history of trauma (OR 4.59, 95% CI 2.93–7.17,p ≤ 0.001), and family history of MSP (OR 4.59, 95% CI 1.36–2.68,p = 0.0002). On multivariate analysis, factors associated with MSP in the previous week and last year were familial history of MSP (p = 0.0457) (p = 0.0024), respectively, and a history of trauma (p ≤ 0.001).ConclusionMSP had a high prevalence among Syrian medical students, especially female students, those with history of trauma, and those with a family history of musculoskeletal disorders (MSD). This major health problem should be known to medical institutions, and awareness programs are required.
Correlation of apolipoprotein A‐I with T cell subsets and interferon‐ү in coronary artery disease
Authors: Xiong Xinlin , Duan Zonggang , Zhou Haiyan , Huang Guangwei , Niu Li , Luo Zhenhua , Li Wei 
Published: March 2023

AbstractBackgroundThe association of Apolipoprotein A‐I (APOAI) with T cell subsets and interferon‐ү (IFN‐γ) in patients with coronary artery disease (CAD) has been not reported. Thus, this study aimed to investigate the association of APOAI with T cell subsets and IFN‐γ in CAD.MethodsThis study included a total of 107 patients with CAD including acute coronary syndrome and chronic coronary syndrome. T cell subsets, and CD3‐CD56+ natural killer cells were quantified by flow cytometric analysis. The serum concentrations of IFN‐ү were measured by enzyme‐linked immunosorbent assay. Lipid profiles, C‐reactive protein (CRP), and fibrinogen were measured in the clinical laboratory. Clinical data was obtained duration hospitalization.ResultsThe CD4+ T cells were higher in patients of the low‐APOAI group (<median: 1.2 mmol/L) than in patients of the high‐APOAI group(≥median: 1.2 mmol/L) (p < .05). The CD8+ T cells were lower in patients of the low APOAI group than in patients of the high‐APOAI group (p < .05). APOAI was inversely associated with CD4+ T cells, IFN‐γ, and was positively associated with CD8+ T cells (p < .05). No correlation was observed between CD3 + CD56+ cells, regulatory T cells (Tregs), and CD3‐CD56+ natural killer cells and APOAI (p > .05). The high‐density lipoprotein cholesterol (HDL‐C) was also inversely associated with CD4+ T cells (p < .05), and positively associated with CD8+ T cells (p < .05). Lastly, APOA1 and HDL‐C did not correlated with fibrinogen and CRP (p > .05).ConclusionThe present study demonstrated the correlation of APOAI with T cell subsets and IFN‐γ in CAD. These results provided novel information for the regulatory action between APOAI and T cell subsets and inflammatory immunity in CAD.
Serum LL‐37 and inflammatory cytokines levels in psoriasis
Authors: Lao Juanfeng , Xie Zhi , Qin Qunshi , Qin Ru , Li Shangyang , Yuan Yulin 
Published: March 2023

AbstractBackgroundPsoriasis (PsO) is a T‐cell‐associated inflammatory autoimmune dermatitis. Leucine leucine‐37 (LL‐37) is upregulated in PsO patients and correlated with the area and severity of PsO. However, the exact relation between LL‐37 and T cell‐associated inflammation is not well understood. It is very important to clarify the relationship between LL‐37 and inflammatory response for clinical diagnosis and treatment of PsO. This study investigated the serum levels of LL‐37 and inflammatory cytokines, as well as correlations between them in PsO patients, which aimed to provide new ideas for the diagnosis and treatment of PsO.MethodsPsO patients (n = 50) and healthy volunteers (n = 33) were recruited in this study. Skin specimens were stained with hematoxylin and eosin (H&E). The serum levels of LL‐37, T‐helper type 1 (Th1, IFN‐γ), T‐helper type 17 (Th17, IL‐17), T‐helper type 22 (Th22, IL‐22), and T‐helper type 2 cytokines (Th2, IL‐4) were assessed by enzyme‐linked immunosorbent assay. Some of the patients were re‐recruited after treatment to evaluate LL‐37 and cytokines levels.ResultsPathological changes were observed in PsO skin lesions. LL‐37, IFN‐γ, IL‐17, and IL‐22 serum levels were much higher in PsO patients than those in healthy volunteers (p < .001), and posttreatment reduction was observed in five patients. However, no remarkable difference in IL‐4 level (p > .05) was found. LL‐37 level was positively correlated with IFN‐γ, IL‐17, and IL‐22 levels (p < .001) in PsO patients.ConclusionLL‐37 expression was significantly associated with inflammatory response, which may provide us new ideas for diagnosing and monitoring disease activity of PsO.
A rare FGF5 candidate variant (rs112475347) for predisposition to nonsquamous, nonsmall‐cell lung cancer
Authors: Cannon‐Albright Lisa A. , Teerlink Craig C. , Stevens Jeff , Facelli Julio C. , Carr Shamus R. , Allen‐Brady Kristina , Puri Sonam , Bailey‐Wilson Joan E. , Musolf Anthony M. ,   Genetic Epidemiology of Lung Cancer Consortium, Akerley Wallace 
Published: March 2023

AbstractA unique approach with rare resources was used to identify candidate variants predisposing to familial nonsquamous nonsmall‐cell lung cancers (NSNSCLC). We analyzed sequence data from NSNSCLC‐affected cousin pairs belonging to high‐risk lung cancer pedigrees identified in a genealogy of Utah linked to statewide cancer records to identify rare, shared candidate predisposition variants. Variants were tested for association with lung cancer risk in UK Biobank. Evidence for linkage with lung cancer was also reviewed in families from the Genetic Epidemiology of Lung Cancer Consortium. Protein prediction modeling compared the mutation with reference. We sequenced NSNSCLC‐affected cousin pairs from eight high‐risk lung cancer pedigrees and identified 66 rare candidate variants shared in the cousin pairs. One variant in the FGF5 gene also showed significant association with lung cancer in UKBiobank. This variant was observed in 3/163 additional sampled Utah lung cancer cases, 2 of whom were related in another independent pedigree. Modeling of the predicted protein predicted a second binding site for SO4 that may indicate binding differences. This unique study identified multiple candidate predisposition variants for NSNSCLC, including a rare variant in FGF5 that was significantly associated with lung cancer risk and that segregated with lung cancer in the two pedigrees in which it was observed. FGF5 is an oncogenic factor in several human cancers, and the mutation found here (W81C) changes the binding ability of heparan sulfate to FGF5, which might lead to its deregulation. These results support FGF5 as a potential NSNSCLC predisposition gene and present additional candidate predisposition variants.
Intersession experiences and internalized representations of psychotherapy: A scoping review
Authors: Gablonski Thorsten‐Christian , Herrmann Pauline Leonie , Lüdemann Jonas , Andreas Sylke 
Published: March 2023

AbstractIntroductionBetween‐session processes outside the therapy room and beyond the direct interaction between a therapist and client can play an important role in the psychotherapeutic process and outcome. These processes are called intersession experiences and can be seen as internalized mental representations of therapy and/or therapists. Due to the COVID‐19 pandemic, different digital forms of treatment have successfully been implemented and could be relevant even after the end of the COVID‐19 pandemic. Therefore, patients' internalized mental representations may become highly relevant in the future.RationaleThe aim of this study was to conceptually delineate the current state of research on internalized mental representations of therapy or therapists in the period between sessions and to provide an overview of the evidence. In addition, we aimed to identify research gaps to provide a baseline for further research.MethodsFor this purpose, we conducted a scoping review to obtain a comprehensive overview of the evidence and to identify the relevant research gaps. We searched PsycArticles, Medline, PsycINFO, and PSYNDEX for publications on internalized mental representations.ResultsThe final sample comprised 30 publications published from 1989 to 2021. Based on the individual study results, it can be assumed that intersession experiences are of central importance for psychotherapeutic treatment. However, the scoping review showed that there was a large gap in knowledge in the research of intersession experiences. All previous research was barely comparable, and therefore, a generalized statement is not possible.ConclusionFuture research should provide sufficient information about relevant aspects, such as the setting, therapists, and patients, as these factors are likely to have a significant impact on the outcome. Furthermore, better measurements for the assessment of these processes should be developed.
Therapist training in treating sleep problems: A survey study of clinical practice
Authors: Gumport Nicole B. , Gasperetti Caitlin E. , Zieve Garret G. , Harvey Allison G. 
Published: March 2023

AbstractObjectivesMental health care clinicians' training in treating sleep problems was investigated. We examined clinicians' (1) prior training in providing treatment for sleep problems, (2) interest in receiving training in treatment for sleep problems, and (3) perceptions of the importance of treating sleep problems and interest in incorporating sleep treatments into their practices.MethodsAn online survey was completed by 137 clinicians.ResultsThe majority of clinicians (61.31%) reported receiving prior training in treating sleep problems, most commonly in the form of a workshop and after receiving a graduate degree. Most clinicians reported interest in receiving further training in treating sleep problems. Clinicians reported that the majority (66.67%) of their clients experience sleep problems, yet reported that they address sleep with fewer than half of clients. Addressing sleep in treatment was rated as “somewhat” to “very” important and most clinicians indicated further interest in receiving training in treating sleep.ConclusionsMental health care clinicians receive limited training in treating sleep problems. As clinicians are interested in gaining further training to address sleep concerns within their clinical practice, training programs and continuing education programs should consider increasing the amount of programming in sleep treatment and assessment.
Microbial fuel cell review: thermodynamic and infuencing factors, exoelectrogenic bacteria, anode and cathode configuration
Authors: Abdulwahhab Maha A , Najim Sarmad T , Abdulwahhab Maha Allawi 
Published: March 2023

AbstractOver the past 20 years the scientific community has become interested in microbial fuel cell microbial fuel cell (MFC) technology, because it offers the potential for the direct conversion of organic waste into power generation through microbially catalysed anodic and microbial–enzymatic–abiotic cathodic electrochemical reactions. Several facts about the technology are taken into account in this evaluation. A brief history of abiotic to biological fuel cells is presented, as well as a presentation of microbial fuel cells and a description of the concept of a microbial fuel cell in a broader range of derivative technologies known as bio‐electrochemical systems with biofilm formation, aerobic and anaerobic digestion of organic materials contained in the substrates and how electrons transfer from the surface of the biofilm to the outer circle. Microbial electrolysis cells, and electro‐synthesis cells are briefly discussed. MFC can be improved through the understanding of previous studies by defining the method of work and the theoretical foundations on which they are built. Moreover, the wide range of criteria that is likely to restrict their performance can be determined by providing a brief explanation of components that make them up. Thermodynamic and biotic factors and the mechanism of operation of these bio‐electrochemical systems need to be considered. A review of the various components that make up the MFC will be proposed, allowing for the illumination of the several scientific locks that continue to limit the technology's effectiveness. This review will provide a discussion of the mechanism of MFCs and provide details about the action of electrically active bacteria in the anode chamber through the generation of electroactive biofilms and the conversion of part of the energy available in the substrates, and this is one of renewable energy which is highlighted by researchers. © 2023 Society of Chemical Industry (SCI).
A systematic comparison reveals dynamic differences in early adaptive immune responses of acute‐resolving versus chronic HBV replication
Authors: Wang Qin , Liu Yanan , Luo Jinzhuo , Yang Shangqing , Wang Lu , Lu Yinping , Feng Xuemei , Yang Xuecheng , Sutter Kathrin , Dittmer Ulf , Lu Mengji , Zheng Xin , Yang Dongliang , Liu Jia 
Published: March 2023

AbstractChronic hepatitis B virus (HBV) infection has been characterized by lack of effective adaptive immune responses which are vital for the viral clearance. However, very little is known about the dynamics of adaptive immune responses during the early phase of chronic HBV infection especially in spleen and liver. Here, we used the hydrodynamic injection (HDI) mouse model to kinetically characterize differences in the features of adaptive immunity, including the frequencies, phenotypes and function of antigen‐presenting cells and T cells in the spleen, peripheral blood mononuclear cells (PBMCs) and liver, of chronic versus acute‐resolving HBV replication (AR). We found that mice with AR mice and mice with chronic HBV replication (CH) mice showed early splenomegaly accompanied by T cell expansion in spleen but not in liver after HDI. Interestingly, the early and continuous increase in HBV‐specific CD8+ T cells in spleen of CH mice was comparable to that in the AR mice. However, the splenic T cells of CH mice showed no activation phenotype compared with those in AR mice. Besides, increases in activated effector CD8+ T cells in PBMCs and liver at later time points were only observed in AR mice but not CH mice. CH mice also showed insufficient expansion of dendritic cells (DCs) in spleen and increased programmed death‐1 expression in DCs of the liver compared to AR mice. The adoptive transfer of total splenocytes or splenic CD8+ T cells of AR mice to CH mice demonstrated that their ability to break HBV tolerance varies at different stages of HBV clearance. Moreover, the adoptive transfer of splenocytes from AR mice induce functional activation of endogenous HBV‐specific CD8+ T cells of CH mice. Our results suggest that early T cell priming and expansion initially happens in the periphery after HBV antigen exposure in acute‐resolving and chronic replication. The paucity of T cell activation, and subsequent migration and liver infiltration is a key feature of the adaptive immune responses during the early phase of CH, which is probably caused by the dysfunction of DCs.