bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk Factors and Characteristics of Checkpoint Inhibitor–Associated Autoimmune Diabetes Mellitus (CIADM): A Systematic Review and Delineation From Type 1 Diabetes
Authors: Wu Linda , Tsang Venessa , Menzies Alexander M. , Sasson Sarah C. , Carlino Matteo S. , Brown David A. , Clifton-Bligh Roderick , Gunton Jenny E. 
Published: May 2023

BACKGROUND
Checkpoint inhibitor–associated autoimmune diabetes mellitus (CIADM) is a distinct form of autoimmune diabetes that is a rare complication of immune checkpoint inhibitor therapy. Data regarding CIADM are limited.

PURPOSE
To systematically review available evidence to identify presentation characteristics and risk factors for early or severe presentations of adult patients with CIADM.

DATA SOURCES
MEDLINE and PubMed databases were reviewed.

STUDY SELECTION
English full text articles from 2014 to April 2022 were identified with a predefined search strategy. Patients meeting diagnostic criteria for CIADM with evidence of hyperglycemia (blood glucose level &gt;11 mmol/L or HbA1c ≥6.5%) and insulin deficiency (C-peptide &lt;0.4 nmol/L and/or diabetic ketoacidosis [DKA]) were included for analysis.

DATA EXTRACTION
With the search strategy we identified 1,206 articles. From 146 articles, 278 patients were labeled with “CIADM,” with 192 patients meeting our diagnostic criteria and included in analysis.

DATA SYNTHESIS
Mean ± SD age was 63.4 ± 12.4 years. All but one patient (99.5%) had prior exposure to either anti-PD1 or anti–PD-L1 therapy. Of the 91 patients tested (47.3%), 59.3% had susceptibility haplotypes for type 1 diabetes (T1D). Median time to CIADM onset was 12 weeks (interquartile range 6–24). DKA occurred in 69.7%, and initial C-peptide was low in 91.6%. T1D autoantibodies were present in 40.4% (73 of 179) and were significantly associated with DKA (P = 0.0009) and earlier time to CIADM onset (P = 0.02).

LIMITATIONS
Reporting of follow-up data, lipase, and HLA haplotyping was limited.

CONCLUSIONS
CIADM commonly presents in DKA. While T1D autoantibodies are only positive in 40.4%, they associate with earlier, more severe presentations.
Full Title: Risk factors and characteristics of checkpoint inhibitor associated autoimmune diabetes (CIADM): a systematic review and delineation from type 1 diabetes
Authors: Wu Linda , Tsang Venessa , M. Menzies Alexander , C. Sasson Sarah , S. Carlino Matteo , A. Brown David , Clifton-Bligh Roderick , E. Gunton Jenny 
Published: May 2023

<p> </p>
<p><strong>Background</strong></p>
<p>Checkpoint inhibitor associated autoimmune diabetes (CIADM) is a distinct form of autoimmune diabetes that is a rare complication of immune checkpoint inhibitor therapy. Data regarding CIADM is limited. </p>
<p><strong>Purpose</strong></p>
<p>To systematically review available evidence to identify presentation characteristics and risk factors for early or severe presentations of adult patients with CIADM. </p>
<p><strong>Data sources</strong></p>
<p>Medline and PubMed databases were reviewed. </p>
<p><strong>Study selection</strong></p>
<p>English full text articles from 2014 to April 2022 were identified using a pre-defined search strategy. Patients meeting diagnostic criteria for CIADM with evidence of hyperglycaemia (blood glucose level >11mmol/L or HbA1c >= 6.5%) and insulin deficiency (C-peptide <0.4nmol/l and/or diabetic ketoacidosis) were included for analysis. </p>
<p><strong>Data extraction</strong></p>
<p>The search strategy identified 1206 papers. From 146 papers 278 patients were labelled with “CIADM”, with 192 patients meeting our diagnostic criteria and included in analysis.</p>
<p><strong>Data synthesis</strong></p>
<p>Mean age was 63.4years (±12.4). All but one patient (99.5%) had prior exposure to either anti-PD1 or anti-PDL1 therapy. Of the 91 patients tested (47.3%), 59.3% had susceptibility haplotypes for type 1 diabetes. Median time to CIADM onset was 12 weeks (IQR 6-24). Diabetic ketoacidosis (DKA) occurred in 69.7%, and initial C-peptide was low in 91.6%. Type 1 diabetes autoantibodies were present in 40.4% (73/179) and were significantly associated with DKA (p=0.0009) and earlier time to CIADM onset (p=0.02).</p>
<p><strong>Limitations</strong></p>
<p>Reporting of follow up data, lipase and HLA haplotyping was limited.</p>
<p><strong>Conclusions</strong></p>
<p>CIADM commonly presents in DKA. While T1D autoantibodies are only positive in 40.4%, they associate with earlier, more severe presentations. </p>
Penganut Kristen Katolik di Gereja Tritunggal Maha Kudus di Badung - Bali dalam Perspektif Tri Hita Karana sebagai Sumber Belajar Sejarah di SMA
Authors: Danasuari Sinta , Purnawati Desak Made Oka , Yasa I Wayan Putra 
Published: May 2023

Penelitian ini bertujuan untuk mengetahui: (1) sejarah berdirinya Gereja Tritunggal Maha Kudus-Tuka, Badung, Bali, (2) penganut Katolik di Gereja Tritunggal Maha Kudus dalam perspektif Tri Hita Karana, dan (3) Potensi Gereja Tritunggal Maha Kudus sebagai sumber belajar sejarah di SMA. Metode penelitian yang digunakan yaitu metode penelitian sejarah yang terdiri dari (1) Heuristik (teknik penentuan informan, observasi, dokmentasi dan wawancara), (2) Kritik Sumber / Verifikasi, (3) Intepretasi, dan (4) Historiografi. Hasil penelitian menunjukkan bahwa: (1) Sejarah masuk dan berkembangnya agama Kristen Katolik di Tuka dan sejarah berdirinya Gereja Tritunggal Maha Kudus yang kemudian diresmikan pada tanggal 14 Februari 1987 oleh Mgr. Vitalis Djebarus SVD. (2) Mendapatkan reaksi positif dari masyarakat Bali khususnya yang beragama non Katolik di Desa Tuka. (3) Potensi Gereja Tritunggal Maha Kudus sebagai sumber belajar sejarah di SMA dapat dilihat dari inkulturasi terhadap budaya serta ornamen gereja. Inkulturasi dapat dilihat meliputi gapura bercorak Hindu, penggunaan penjor, gebogan, pakaian adat Bali, ukiran dinding dengan aksara Bali, serta adanya gamelan dari Bali. Selain itu, aspek Tri Hita Karana dalam Gereja Tritunggal Maha Kudus juga dapat dilihat dari aspek keagamaan, aspek sosial, dan aspek budaya.
Kata Kunci: Gereja, Sejarah, Tri Hita Karana, Pendidikan
Video Animasi Rotasi Bumi dan Akibatnya Berbasis Powtoon
Authors: Kadek Yudik Ariawan  , I Kadek Suartama  , Ndara Tanggu Renda  
Published: May 2023

Motivasi siswa secara keseluruhan masih relatif rendah yang terlihat dari perilaku siswa yang tidak menyukai pembelajaran IPA berdampak pada hasil belajar siswa yang rendah. Tujuan penelitian ini yaitu mengembangkan video animasi rotasi bumi dan akibatnya berbasis Powtoon. Jenis penelitian ini yaitu pengembangan dengan menggunakan model ADDIE. Subjek penelitian ini yaitu 2 ahli media, 2 ahli materi pembelajaran dan 2 guru. Subjek uji coba yaitu siswa kelas IV SD yang berjumlah 12 siswa. Metode pengumpulan data menggunakan observasi, wawancara, dan kuesioner. Instrumen yang digunakan dalam mengumpulkan data yaitu angket. Teknik yang digunakan untuk menganalisis data yaitu analisis deskriptif kualitatif dan kuantitatif. Hasil penelitian yaitu penilaian dari ahli media pembelajaran I yaitu 96,15%, dan ahli II yaitu 90,38%. Hasil penilaian dari ahli materi yaitu ahli I yaitu 95% dan ahli II yaitu 90%. Hasil penilaian kepraktisan dari guru yaitu guru I (97,36%), dan guru II (98,68%). Hasil respon siswa yaitu 97,9%. Disimpulkan bahwa Video Animasi Powtoon Rotasi Bumi valid dan layak digunakan dalam pembelajaran.
β-Lactam resistance in veterinary β-hemolytic Streptococcus species: Are we experiencing a public health or test method crisis?
Authors: Maddock Kelli J. , Gefroh Sarah J. , Burbick Claire R. 
Published: May 2023

Abstract
β-Hemolytic Streptococcus (BHS) species are important pathogens with both human and veterinary significance. In human medicine, BHS are considered universally susceptible to β-lactams while BHS of veterinary origin have been reported with up to 8% β-lactam resistance. Recently, veterinary diagnostic laboratories were made aware of significant variability of test method performance for BHS among laboratories. This article explores potential sources of error in antimicrobial susceptibility test performance and result interpretation that may have contributed to the unusual rates of resistance to β-lactams observed in this bacterial species. In addition, potential impacts to research, clinical practice, surveillance, and public health will be discussed.
Thermal and Mechanical Properties of Materials with Adverse Effect on the Environment
Authors: Smutný Ladislav , Vitázek Ivan , Mareček Jan 
Published: May 2023

Abstract
In this study, we evaluate the thermal and mechanical properties of materials based on polypropylene (PP), high-density polyethylene (HDPE), and polyethylene terephthalate (PET) using the thermogravimetric analysis and impulse excitation technique. The results show that even if the melted input material together with the pressure of ~4 MPa was used to produce the samples, we can find small cavities around the sand grains in the samples. In case of thermal stability, the results show that in case of HDPE + PET combination, higher temperature should be used. Besides that, the results show that sand should increase the Young’s modulus of the samples from recycled materials.
Determining the Suitability of Various Surface Treatment Methods with the Control of Blasting Time with Respect to the Quality of Powder Coating
Authors: Neškudla Michal , Jeníček Lukáš , Malaťák Jan 
Published: May 2023

Abstract
The paper is focused on steel surface processing to ensure an improved adhesion of applied powder layer. Mechanical pre-treatment, chemical pre-treatment and their combination were used to compare their results with each other and to find out the pre-treatment that affected the final outcome the most. The final score was determined by the grid method. The outcome displayed a huge mutual dependency between the result and a kind of various surface treatments. The method with no pre-treatment was by far the worst, followed by the mechanical pre-treatment only, followed by the chemical pre-treatment only, and finally by their combination. The time of blasting affects the final outcome. Through the grid method, coating thickness, and aesthetic test it was confirmed that an optimal blasting time of 5 min provides the best outcome.
The Stakeholder Spectrum. The History and the Current State of Participatory Film in Hungary
Authors: Müllner András 
Published: May 2023

AbstractThe Research Centre for Minor Media/Culture (founded at the Department of Media and Communication, ELTE University, Hungary) includes a number of research areas and work processes. One of them is to reveal the history and to map the actual state of the participatory film in Hungary, concieved not just as a visual social research method, but as a wide spectrum on which there are many different examples according to the depth and nature of the involvement of the stakeholders. The academic activities in the Research Centre cover the historical and theoretical aspects of participatory film, its foreign and Hungarian antecedents, contemporary national and international examples. Following the definitions of the field and examples from abroad, the author attempts to delimit the possible sub-themes that belong or could belong to the scope of participatory film. The author also mentions some aspects that seem useful for the analysis of the research topics, specifically film examples. From these varied examples a broad repository of participatory-based film will hopefully emerge: the stakeholder spectrum.1
What Does It Mean to Be a Good Teacher? Beliefs of Future Secondary School Teachers During Their Initial Training in Spain
Authors: Rubio Juan García 
Published: May 2023

Abstract
Teachers play a key role in students’ learning, especially when it comes to students who have more difficulties in the classroom. Initial teacher training contributes to achieving more competent teachers who are capable of successfully facing the start of their teaching profession, and students’ beliefs about what it means to be a good teacher are key. The prior beliefs and ideas with which future teachers come to university classrooms determine their first teaching identity and the beginning of their professional practice. In this paper, research focused on the beliefs of future secondary school teachers regarding what they consider constitutes a good teacher. A qualitative, biographical-descriptive methodology was used, in which the teaching students’ narratives were used as a starting point to establish what characterizes a good teacher. The results show that future secondary school teachers place the relationship between the teacher and the students as the key factor when it comes to being a good teacher, above any other factor, which includes aspects related to the way in which the curriculum is taught.
Terrorism - A Concept Under Construction: The Use of the Term in Mexican Congressional Debates in the First Half of the XX Century
Authors: Semboloni Lara 
Published: May 2023

Abstract
The paper focuses on the perceptions of “terrorism” that Mexican politicians developed in the initial decades of the 20th century, and which definitions did emerge in the Congressional debates. The aim is to assess which events were crucial in shaping an official narrative of the phenomenon, and, in doing so, it will apply the Foucaultian theory, looking at the issue of discontinuity, which provides an analytical key to assess the whens and whys for the emergence of a State-centered discourse on terrorism.
Documenting Distinctive Features of Indigenous Bapedi Music
Authors: Lebaka Morakeng Edward Kenneth 
Published: May 2023

Abstract
In the Bapedi music tradition, characteristics, and the role of indigenous music in the community is one area that requires scholarly attention. An investigation into the use and influence of pure, natural, and authentic indigenous music in the context of religion and wellbeing is inevitable. The purpose of this study was to investigate the significant role played by indigenous music in the daily lives of Bapedi people, as well as the characteristics of the music. To address the objectives of the study, the following primary research question was considered: what is the cultural relevance of indigenous Bapedi music? The primary sources for data collection include observations and oral interviews that were conducted through face-to-face interaction. The interviews were aimed at eliciting first-hand information on the knowledge of the subject matter. The secondary sources included among others, materials such as journal articles, books and theses, and of course personal experience. The results have shown that indigenous Bapedi music is a social activity in which everyone participates and requires coordinated cooperation. It was concluded that Bapedi people use a wide variety of sounds within a single performance. The impression created during observations and interviews was that music rhythm and percussive sounds are highly emphasized in indigenous Bapedi music.
Challenges for the Bulgarian Companies in the Implementation of Sustainability Practices
Authors: Dimitrov Ivan 
Published: May 2023

Abstract
The topic of sustainability, and in particular the sustainability practices of companies, is especially relevant nowadays. The introduction of such practices is very important for Eastern European countries, including Bulgaria. This study is part of a large-scale university project (UNWE, Sofia) that focuses precisely on sustainability practices in international business. The aim is to find out if Bulgarian companies are familiar with sustainable practices and whether they apply them correctly in their daily operations. This is achieved via analysis and synthesis of results from a survey. The summarized data of the aforementioned survey is part of the whole project and represents the policies for sustainable development in specially selected Bulgarian private companies. Each of the companies included in the survey is ISO 14000 certified (the international standards for environmental management) and this condition determines the scope of the study. The research could serve as a basis for better understanding of the integration process of sustainability practices in Bulgarian companies.
Corporate Social Responsibility - Business Opportunity or Obligation for Georgian Companies
Authors: Kasradze Tea , Machkhashvili Sopio 
Published: May 2023

Abstract
CSR is a relatively new concept for Georgia. Its history is not even two decades old, and the development process is taking place at a slow pace. In recent years, the concept of social responsibility has been more or less accepted by large businesses. From unsystematic CSR measures companies are slowly moving to a strategic approach, although their social initiatives are mainly focused on increasing the well-being of vulnerable groups of society. On the one hand, this is due to the insufficient level of awareness of CSR in the business sector, and on the other hand, the limited expectations of society because the public’s perception of CSR is mainly related to charity. The paper presents an analysis of the modern trends in the development of CSR in Georgia using qualitative and quantitative secondary data. It is based on the works and studies of various scientists. Qualitative analysis, namely statistical and thematic analysis methods are used as the method of analysis.
Impact of Sustainability on the Strategic Direction of Luxury Companies
Authors: Böhnert Arno , Blaschke Florian , Biewendt Marcel 
Published: May 2023

Abstract
Today’s society is undergoing a paradigm shift driven by the megatrend of sustainability. This undeniably affects all areas of Western life. This paper aims to find out how the luxury industry is dealing with this change and what adjustments are made by the companies. For this purpose, interviews were conducted with managers from the luxury industry, in which they were asked about specific measures taken by their companies as well as trends in the industry. In a subsequent evaluation, the trends in the luxury industry were summarized for the areas of ecological, social, and economic sustainability. It was found that the area of environmental sustainability is significantly more focused than the other sub-areas. Furthermore, the need for a customer survey to validate the industry-based measures was identified.
A Study on Key Retailing Strategies of Carrefour and Its Intervention Plan During the Pandemic (Covid-19): UAE
Authors: Bhalla Reema , Bhalla Vivek 
Published: May 2023

Abstract
An economy is governed by its markets and for a growing economy retailing is a blooming industry. The secret of successful retailing is to give the customers what they want. Keeping this in mind a French Retailer, ‘CARREFOUR’ is progressing high across various nations of the world keeping in mind the cross national and demographic styles of various countries. It adapts itself with the form and culture of every nation and penetrates deep though its roots. The pandemic of COVID-19, gave carrefour an immense exposure of the new marketing plans which rescued it and gave it a new strategic insight. The scope of this paper is to study key strategies of this retail giant in Dubai (UAE). This paper also focuses on the various strategies adopted by this retail joint keeping in mind the complete marketing mix and adoption of the new era of online shopping post the pandemic time.
A Discourse Map on Counseling International Students in Korea
Authors: Kim Youngsoon , Oh Youngsub 
Published: May 2023

Abstract
The number of international students has drastically increased over a decade in Korea. And a psychological demand to make them successfully adjust their college life in Korea has also increased. Accordingly, it is necessary to explore how international student-focused counseling research has unfolded in Korea. To this end, this study provides research trend in Korea through a content analysis of 79 theses and articles published over recent two decades (1996-2016). Over 140 research contents are classified into 10 categories, including cultural adjustment, psychological health, and career and vocation as the main three categories. Frequency of conceptions or terms in each category, and relationship between those conceptions are analyzed. Based on the content analysis, a discourse map is finally drawn. Also, future research agendas are suggested.
Bosnian Multiconfessionalism as a Foundation for Intercultural Dialogue
Authors: Pilarska Justyna 
Published: May 2023

Abstract
Muslim communities in the Balkans where the practice of Islam had been developed in the European context, can be used as an exemplification of the bridge between the Islamic East and the Christian West. Although for over 400 years Bosnia was under the Ottoman rule, Muslims became one of the many first Yugoslav, and then Bosnian communities, contributing to the dynamic, yet moderate area of ontological and axiological negotiations within the cultural borderland, sharing the living space with members of the Orthodox church, Catholics, a small Jewish community, and even Protestants. The history of the Muslim-Christian contacts in Bosnia involves both the examples of collisions, as well as encounters, initiated both by Christians, and by Muslims. This article analyzes the religious diversity (multiconfessionalism) in the historical and contemporary cultural and social context of Bosnia-Herzegovina, revealing its specificity, dynamics and (often unsuccessful) attempts to conceptualize it from the perspective of the Eurocentric discourse. The aim is not only to portray this religiously diverse makeup, but also to emphasize its potential for establishing ground for intercultural dialogue.
Self-Affirmation Effect on Risk Perception and the Moderating Role of Self-Efficacy in Anti-Alcohol Messages
Authors: Stanojlović Milena , Cambra Ubaldo Cuesta , Paredes Borja , Lamprinakos Grigorio , Stavraki Maria 
Published: May 2023

Abstract
The beneficial effect of self-affirmation on the reduction of people’s defensive responses and the increase in message acceptance has been widely demonstrated in different health-related topics. However, little is known about the specific conditions in which self-affirmation strategies might be more effective. Our objective is to explore the interplay of self-affirmation and self-efficacy in the context of alcohol consumption. Recruited participants were randomly assigned to either a self-affirmation group or a no-treatment group and exposed to a video describing several consequences of alcohol consumption. Following the message exposure, participant’s drinking refusal self-efficacy was measured together with their perceived risk of daily alcohol intake. In line with our predictions, self-affirmed individuals who reported higher drinking refusal self-efficacy perceived daily alcohol consumption as a significantly higher risk than those who were assigned to the no-treatment condition. In contrast, for individuals with low drinking refusal self-efficacy, there was no significant difference in the perceived risk between the self-affirmed and the non-affirmed. We predicted and showed that self-affirmation influences the risk perception of daily drinking only for the people who reported higher drinking refusal self-efficacy. This indicates that self-efficacy could be an important factor that moderates the effect of self-affirmation in alcohol consumption domain.
Mobbing/Bullying Behaviour and Mental Health Difficulties of a Victim of Mobbing
Authors: Dobrowolska Małgorzata , Izydorczyk Bernadetta 
Published: May 2023

Abstract
The paper provides the theoretical background of mobbying/bullying and description of a case study concerning a victim of mobbing. In conclusion, reflections concerning counteracting of bullying are provided. Each work environment, regardless the form of employment or the specificity of a job, creates conditions for more or less ethical behaviour