bluuebunny/crossref_metadata_2025_split huggingface dataset:
Desa Genting: Desa Generasi Emas Bebas Stunting di Meteseh Utara Kota Magelang
Authors: Mareta Reni , Puspitasari Dhita , Hanifah Ivon , Santri Kamelya Nur , Dita Prabasari Ayu , Ananda Saputri Maulidya 
Published: August 2023

Stunting adalah kondisi dimana tinggi badan seseorang lebih pednek dibandingkan dengan orang lain yang sebaya (Sandjojo 2017). Tujuan dari kegiatan pengabdian pada masyarakat terpadu (PPMT) dengan tema “Membangun Desa Sehat Generasi Emas Bebas Stunting (Desa GENTING) di Meteseh Utara Kota Magelang” adalah untuk meningkatkan pengetahuan masyarakat dan meningkatkan tingkat pemahaman masyarakat mengenai stunting, dikarenakan di Desa Meteseh Utara masih terdapat beberapa anak yang mengalami stunting, selain itu juga mempunyai tujuan untuk mengentaskan masalah stunting. Metode yang dilakukan dalam pengabdian ini adalah dengan memberikan sosialisasi tentang stunting, pembuatan makanan tambahan menggunakan bahan dasar daun kelor, pengolahan sampah. Hasil dari kegiatan ini adalah masyarakat Desa Meteseh memahami tentang stunting dan pencegahannya, pengolahan daun kelor untuk meningkatkan status gizi keluarga dan pengolahan limbah sampah untuk meningkatkan penghasilan keluarga. Kesimpulannya bahwa kegiatan pengabdian masyarakat ini bisa menambah pengetahuan, dan ketrampilan masyarakat dalam mengolah daun kelor menjadi makanan bergizi dan mengolah sampah menjadi karya yang mempunyai nilai jual.
“Shadow of the Empire”: Rethinking Russian Imperial Sovereignty in the Context of the War against Ukraine, 2022
Authors: Zaporozhchenko Ruslan 
Published: August 2023

Abstract
Russia’s military invasion of Ukraine demonstrated the Kremlin’s imperial ambitions. The invasion was not only a shocking event, but also a process of geopolitical transformation. Russia, which has a long history of imperialism, in the 21st century is trying to break the established global world order and propose an alternative one. But the tools it uses are tools of violence, domination, blackmail, and intimidation. This is particularly important to explore in the context of the Russian leadership’s construction of imperial sovereignty, a form of political power used to expand and consolidate the empire’s influence in a particular geopolitical space: the post-Soviet space. This article aims to show the nature of Russian imperial sovereignty as well as the mechanisms of its dissemination, which are modus operandi – dynamic structures of reproduction of the system of power relations.
Segmentasi Jalan Berlubang Citra Jalan Raya Menggunakan Metode Thresholding Dan K-Means
Authors: Sukmawati Linda , Sadikin Rifki 
Published: August 2023

Abstract - One of the important meanings for human life is the road. The road is used as a means of transportation which has very useful planning in the development of human life. In 2018, based on statistical data, the number of motor vehicle users in Indonesia is increasing every year, reaching 146,858,759 units. Seeing the number of the enhancement of motor vehicle users, the impact occured. Many roads are damaged and the conditions are very unsettling and concerned for the road users. One of the most common damages is that there are many holes in the road, which can increase the accidents’ risk. Based on science and technology development, one of the causes for the lengthy time to repair road damage is due to calculating the area of each damage manually and it takes a relatively long time. For this reason, this study aims to perform image processing in the form of segmentation on the image of a potholed road on the highway using the Thresholding algorithm and K-Means, followed by the calculation of the area and perimeter of the hole. The results of this study were obtained with 106 images of potholed roads, then segmented and calculated the area and circumference can be read properly using a program that has been designed. Keywords: Segmentation, Thresholding, K-Means
Detection and Measurement of Displacement and Velocity of Single Moving Object in a Stationary Background
Authors: R. Almaddah Amr Reda. , Ahmad Tauseef , Dubai Abdullah 
Published: August 2023

The traditional Harris detector are sensitive to noise and resolution because without the property of scale invariant. In this research, The Harris corner detector algorithm is improved, to work with multi resolution images, the technique has also been working with poor lighting condition by using histogram equalization technique. The work we have done addresses the issue of robustly detection of feature points, detected multiple of local features are characterized by the intensity changes in both horizontal and vertical direction which is called corner features. The goal of this work is to detect the corner of an object through the Harris corner detector with multiple scale of the same image. The scale invariant property applied to the Harris algorithm for improving the corner detection performance in different resolution of the same image with the same interest point. The detected points represented by two independent variables (x, y) in a matrix (x, y) and the dependent variable f are called intensity of interest points. Through these independent variable, we get the displacement and velocity of object by subtracting independent variable f(x,y) at current frame from the previous location f ̀((x,) ̀(y,) ̀) of another frame. For further work, multiple of moving object environment have been taken consideration for developing algorithms.
Application of gravity and remote sensing data to groundwater potential in Wadi Ar-Ramah, Saudi Arabia
Authors: Mohamed Ahmed , Alshehri Fahad 
Published: August 2023

Water scarcity is developing in the Middle East as a result of the region’s growing population and tremendously advanced agricultural and industrial sectors. Saudi Arabia is the Middle East country with the highest water consumption, so there is an urgent need to take action, and new technology advancements in geophysical measurements allow for the monitoring of groundwater. Wadi Ar-Ramah is one region that has witnessed significant agricultural expansion as well as a serious over-exploitation of the groundwater resources that are available there. Depletion rate in groundwater of the Wadi Ar-Ramah basin at eastern Saudi Arabia was determined for the time interval of 04/2002 to 12/2021 using a combination of gravity data from the Gravity Recovery and Climate Experiment (GRACE) mission and results of land surface models. The findings are: 1) the average yearly rainfall rate was computed at 87.7 mm yr−1 over the Wadi Ar-Ramah; 2) the terrestrial water storage variation (ΔTWS) was computed at −1.216 ± 0.013 cm yr−1; 3) the GLDAS-derived soil moisture (ΔSMS) was minimal at −0.32 ± 0.025 mm yr−1; 4) the GRACE-derievd groundwater decreasing rate was calculated at 1.212 ± 0.012 cm yr−1; 5) the relief of the ground surface is producing northeasterly streams that carry the minimal surface water to the east; 6) our integrated method provides a repeatable and cost-effective approach.
Hyperspectral remote sensing technology for water quality monitoring: knowledge graph analysis and Frontier trend
Authors: Ma Taquan , Zhang Donghui , Li Xusheng , Huang Yao , Zhang Lifu , Zhu Zhenchang , Sun Xuejian , Lan Ziyue , Guo Wei 
Published: August 2023

Water environment health assessment is one of the vital fields closely related to the quality of human life. The change of material contained in water will lead to the reflectance change of hyperspectral remote sensing data. According to this phenomenon, the water quality parameters are calculated to achieve the purpose of water quality monitoring. Series knowledge graphs in this field are drawn after analyzing 564 publications from WOS (Web of Science) and EI (The Engineering Index) databases since 1994 with the support of VOSviewer and CiteSpace. Including statistics of documents publication time, contribution analysis, the influence of publications and journals, and the influence of funding institutions. It is concluded that the research trend of hyperspectral water quality monitoring is the machine learning algorithm based on UAV (Unmanned Aerial Vehicle) hyperspectral instrument data by analyzing scientific research cooperation, keyword analysis, and research hotspots. The whole picture of the research is obtained in this field from four subfields: application scenarios, data sources, water quality parameters, and monitoring algorithms in this paper. It is summarized that the miniaturization, integration, and intelligence of hyperspectral sensors will be the research trend in the next 10 years or even longer. The conclusions have significant reference values for this field.
Resolving complex structural variants via nanopore sequencing
Authors: Romagnoli Simone , Bartalucci Niccolò , Vannucchi Alessandro Maria 
Published: August 2023

The recent development of high-throughput sequencing platforms provided impressive insights into the field of human genetics and contributed to considering structural variants (SVs) as the hallmark of genome instability, leading to the establishment of several pathologic conditions, including neoplasia and neurodegenerative and cognitive disorders. While SV detection is addressed by next-generation sequencing (NGS) technologies, the introduction of more recent long-read sequencing technologies have already been proven to be invaluable in overcoming the inaccuracy and limitations of NGS technologies when applied to resolve wide and structurally complex SVs due to the short length (100–500 bp) of the sequencing read utilized. Among the long-read sequencing technologies, Oxford Nanopore Technologies developed a sequencing platform based on a protein nanopore that allows the sequencing of “native” long DNA molecules of virtually unlimited length (typical range 1–100 Kb). In this review, we focus on the bioinformatics methods that improve the identification and genotyping of known and novel SVs to investigate human pathological conditions, discussing the possibility of introducing nanopore sequencing technology into routine diagnostics.
Neutrophils: a subgroup of neglected immune cells in ALS
Authors: Cao Wen , Fan Dongsheng 
Published: August 2023

Amyotrophic lateral sclerosis (ALS) is a chronic, progressive neurodegenerative disease characterized by the loss of motor neurons. Dysregulated peripheral immunity has been identified as a hallmark of ALS. Neutrophils, as the front-line responders of innate immunity, contribute to host defense through pathogen clearance. However, they can concurrently play a detrimental role in chronic inflammation. With the unveiling of novel functions of neutrophils in neurodegenerative diseases, it becomes essential to review our current understanding of neutrophils and to recognize the gap in our knowledge about their role in ALS. Thus, a detailed comprehension of the biological processes underlying neutrophil-induced pathogenesis in ALS may assist in identifying potential cell-based therapeutic strategies to delay disease progression.
Small carbon stocks in sediments of Baltic Sea eelgrass meadows
Authors: Billman Maja , Santos Isaac R. , Jahnke Marlene 
Published: August 2023

Seagrass meadows act as an effective carbon sink and store carbon in the sediments for substantial periods of time. The drivers of carbon sequestration are complex, and global and regional estimates of carbon stocks have large uncertainties. Here, we report new carbon stock estimates from 14 sites along the Swedish coast and compile existing literature to estimate the magnitude of carbon stocks of Zostera marina (eelgrass) meadows in the Baltic Sea. Eelgrass meadows in the Baltic Sea have considerably lower carbon content and lower stocks (0.25 ± 0.21% DW, 635 ± 321 g C m-2) than in the Kattegat-Skagerrak region (3.25 ± 2.78% DW, 3457 ± 3382 g C m-2) and the average for temperate regions in general (1.4 ± 0.4% DW, 2721 ± 989 g C m-2). Unfavorable growing conditions for eelgrass in the Baltic Sea often lead to meadows occurring in areas of high hydrodynamics, preventing significant carbon accumulation. Stable isotopes revealed that the dominating source of organic carbon in the meadows was planktonic, further highlighting that Baltic Sea eelgrass meadows are not major carbon reservoirs in comparison to unvegetated sediments and other seagrass areas. The results also highlight that environmental conditions drive intraspecific variation of carbon sequestration on large spatial scales. Overall, the carbon stocks and sequestration potential in eelgrass meadows of the Baltic Sea are small compared to other temperate regions.
Inhibitory to non-inhibitory evolution of the ζ subunit of the F1FO-ATPase of Paracoccus denitrificans and α-proteobacteria as related to mitochondrial endosymbiosis
Authors: Mendoza-Hoffmann Francisco , Yang Lingyun , Buratto Damiano , Brito-Sánchez Jorge , Garduño-Javier Gilberto , Salinas-López Emiliano , Uribe-Álvarez Cristina , Ortega Raquel , Sotelo-Serrano Oliver , Cevallos Miguel Ángel , Ramírez-Silva Leticia , Uribe-Carvajal Salvador , Pérez-Hernández Gerardo , Celis-Sandoval Heliodoro , García-Trejo José J. 
Published: August 2023

Introduction: The ζ subunit is a potent inhibitor of the F1FO-ATPase of Paracoccus denitrificans (PdF1FO-ATPase) and related α-proteobacteria different from the other two canonical inhibitors of bacterial (ε) and mitochondrial (IF1) F1FO-ATPases. ζ mimics mitochondrial IF1 in its inhibitory N-terminus, blocking the PdF1FO-ATPase activity as a unidirectional pawl-ratchet and allowing the PdF1FO-ATP synthase turnover. ζ is essential for the respiratory growth of P. denitrificans, as we showed by a Δζ knockout. Given the vital role of ζ in the physiology of P. denitrificans, here, we assessed the evolution of ζ across the α-proteobacteria class.Methods: Through bioinformatic, biochemical, molecular biology, functional, and structural analyses of several ζ subunits, we confirmed the conservation of the inhibitory N-terminus of ζ and its divergence toward its C-terminus. We reconstituted homologously or heterologously the recombinant ζ subunits from several α-proteobacteria into the respective F-ATPases, including free-living photosynthetic, facultative symbiont, and intracellular facultative or obligate parasitic α-proteobacteria.Results and discussion: The results show that ζ evolved, preserving its inhibitory function in free-living α-proteobacteria exposed to broad environmental changes that could compromise the cellular ATP pools. However, the ζ inhibitory function was diminished or lost in some symbiotic α-proteobacteria where ζ is non-essential given the possible exchange of nutrients and ATP from hosts. Accordingly, the ζ gene is absent in some strictly parasitic pathogenic Rickettsiales, which may obtain ATP from the parasitized hosts. We also resolved the NMR structure of the ζ subunit of Sinorhizobium meliloti (Sm-ζ) and compared it with its structure modeled in AlphaFold. We found a transition from a compact ordered non-inhibitory conformation into an extended α-helical inhibitory N-terminus conformation, thus explaining why the Sm-ζ cannot exert homologous inhibition. However, it is still able to inhibit the PdF1FO-ATPase heterologously. Together with the loss of the inhibitory function of α-proteobacterial ε, the data confirm that the primary inhibitory function of the α-proteobacterial F1FO-ATPase was transferred from ε to ζ and that ζ, ε, and IF1 evolved by convergent evolution. Some key evolutionary implications on the endosymbiotic origin of mitochondria, as most likely derived from α-proteobacteria, are also discussed.
Continuous theta burst stimulation over right cerebellum for speech impairment in Parkinson’s disease: study protocol for a randomized, sham-controlled, clinical trial
Authors: Zhu Xiaoxia , Dai Guangyan , Wang Meng , Tan Mingdan , Li Yongxue , Xu Zhiqin , Lei Di , Chen Ling , Chen Xi , Liu Hanjun 
Published: August 2023

BackgroundSpeech impairment is a common symptom of Parkinson’s disease (PD) that worsens with disease progression and affects communication and quality of life. Current pharmacological and surgical treatments for PD have inconsistent effects on speech impairment. The cerebellum is an essential part of sensorimotor network that regulates speech production and becomes dysfunctional in PD. Continuous theta-burst stimulation (cTBS) is a non-invasive brain stimulation technique that can modulate the cerebellum and its connections with other brain regions.ObjectiveTo investigate whether cTBS over the right cerebellum coupled with speech-language therapy (SLT) can improve speech impairment in PD.MethodsIn this randomized controlled trial (RCT), 40 patients with PD will be recruited and assigned to either an experimental group (EG) or a control group (CG). Both groups will receive 10 sessions of standard SLT. The EG will receive real cTBS over the right cerebellum, while the CG will receive sham stimulation. Blinded assessors will evaluate the treatment outcome at three time points: pre-intervention, post-intervention, and at a 12-week follow-up. The primary outcome measures are voice/speech quality and neurobehavioral parameters of auditory-vocal integration. The secondary outcome measures are cognitive function, quality of life, and functional connectivity determined by resting-state functional magnetic resonance imaging (fMRI).SignificanceThis trial will provide evidence for the efficacy and safety of cerebellar cTBS for the treatment of speech impairment in PD and shed light on the neural mechanism of this intervention. It will also have implications for other speech impairment attributed to cerebellar dysfunctions.Clinical trial registrationwww.chictr.org.cn, identifier ChiCTR2100050543.
Behavioral effects of adult male mice induced by low-level acetamiprid, imidacloprid, and nicotine exposure in early-life
Authors: Saito Hirokatsu , Furukawa Yusuke , Sasaki Takahiro , Kitajima Satoshi , Kanno Jun , Tanemura Kentaro 
Published: August 2023

IntroductionAcetamiprid (ACE) and imidacloprid (IMI), the neonicotinoid chemicals, are widely used as pesticides because of their rapid insecticidal activity. Although these neonicotinoids exert very low toxicity in mammals, the effects of early, low-level, chronic exposure on the adult central nervous system are largely unclear. This study investigated the effects of low-level, chronic neonicotinoids exposure in early life on the brain functions of adult mice, using environmentally relevant concentrations.MethodsWe exposed mice to an acceptable daily intake level of neonicotinoids in drinking water during the prenatal and postnatal periods. Additionally, we also exposed mice to nicotine (NIC) as a positive control. We then examined the effects on the central nervous system in adult male offspring.ResultsIn the IMI and NIC exposure groups, we detected behavior that displayed impairment in learning and memory. Furthermore, immunohistochemical analysis revealed a decrease in SOX2 (as a neural stem cell marker) and GFAP (as an astrocyte marker) positive cells of the hippocampal dentate gyrus in the IMI and NIC exposure groups compared to the control group.DiscussionThese results suggest that exposure to neonicotinoids at low levels in early life affects neural circuit base formation and post-maturation behavior. Therefore, in the central nervous system of male mice, the effects of low-level, chronic neonicotinoids exposure during the perinatal period were different from the expected effects of neonicotinoids exposure in mature animals.
The characteristics of brain network in patient with post-stroke depression under cognitive task condition
Authors: Peng Yu , Zheng Yang , Yuan Ziwen , Guo Jing , Fan Chunyang , Li Chenxi , Deng Jingyuan , Song Siming , Qiao Jin , Wang Jue 
Published: August 2023

ObjectivesPost-stroke depression (PSD) may be associated with the altered brain network property. This study aimed at exploring the brain network characteristics of PSD under the classic cognitive task, i.e., the oddball task, in order to promote our understanding of the pathogenesis and the diagnosis of PSD.MethodsNineteen stroke survivors with PSD and 18 stroke survivors with no PSD (non-PSD) were recruited. The functional near-infrared spectroscopy (fNIRS) covering the dorsolateral prefrontal cortex was recorded during the oddball task state and the resting state. The brain network characteristics were extracted using the graph theory and compared between the PSD and the non-PSD subjects. In addition, the classification performance between the PSD and non-PSD subjects was evaluated using features in the resting and the task state, respectively.ResultsCompared with the resting state, more brain network characteristics in the task state showed significant differences between the PSD and non-PSD groups, resulting in better classification performance. In the task state, the assortativity, clustering coefficient, characteristic path length, and local efficiency of the PSD subjects was larger compared with the non-PSD subjects while the global efficiency of the PSD subjects was smaller than that of the non-PSD subjects.ConclusionThe altered brain network properties associated with PSD in the cognitive task state were more distinct compared with the resting state, and the ability of the brain network to resist attack and transmit information was reduced in PSD patients in the task state.SignificanceThis study demonstrated the feasibility and superiority of investigating brain network properties in the task state for the exploration of the pathogenesis and new diagnosis methods for PSD.
Magnetic resonance imaging features of bile duct adenoma
Authors: Huang Mengyue , Huang Mengna , Gao Xuemei , Zhang Yong , Cheng Jingliang , Zhu Jinxia , Li Caixia , Liu Jingjing 
Published: August 2023

ObjectivesTo evaluate the magnetic resonance imaging (MRI) features of bile duct adenoma.MethodsThe data of 28 patients [with 32 pathologically confirmed bile duct adenomas, including 15 with malignant change (malignant group) and 17 without malignant change (benign adenoma group)] were retrospectively reviewed. Abdominal MRI was performed for all patients; in addition, dynamic enhanced MRI was performed for 18 lesions. The MRI features, including lesion location, maximum size, morphology, signal characteristics, enhancement type, and appearance of the bile duct, were assessed by two abdominal radiologists. Apparent diffusion coefficient (ADC) values were measured and compared.ResultsOf the 32 bile duct adenomas, 22 (68.75%) involved the common bile duct (CBD). While 14/32 (43.75%) lesions presented as focal eccentric-type masses, 9/32 (28.13%) presented as plaque-like masses, 4/32 (12.50%) as bile duct casting masses, and 5/32 (15.62%) as infiltrative masses. A frond-like superficial appearance was seen in 8/32 (25%) lesions. Infiltrative masses were significantly more common in the malignant group than in the benign adenoma group (P = 0.015). While 23/32 (71.88%) lesions were isointense on T1-weighted imaging (T1WI), 24/32 (75%) were hyperintense on T2-weighted imaging (T2WI). Bile duct dilatation was present upstream of the lesion in all cases. Bile duct dilatation at the lesion was seen in 24/32 (75%) cases and downstream of the lesion in 6/32 (18.75%) cases. Of the 18 lesions that underwent dynamic enhanced MRI, 14 (77.78%) showed moderate enhancement and 13 (72.22%) showed persistent enhancement. On diffusion-weighted imaging (DWI), 27/32 (84.37%) lesions showed hyperintensity. Mean ADC value was comparable between the malignant group and the benign adenoma group (P = 0.156).ConclusionsBile duct adenoma primarily presents as intraductal growth in the CBD, usually with bile duct dilatation at the lesion site or upstream to it. Most lesions are isointense on T1WI, are hyperintense on T2WI and DWI, and show moderate enhancement. A superficial frond-like appearance of the lesion and bile duct dilatation at the lesion or downstream to it might be characteristics of bile duct adenoma. An infiltrative appearance might indicate malignant transformation.