bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cycle exercise training and muscle mass: A preliminary investigation of 17 lower limb muscles in older men
Authors: Naruse Masatoshi , Vincenty Caroline S. , Konopka Adam R. , Trappe Scott W. , Harber Matthew P. , Trappe Todd A. 
Published: August 2023

AbstractCycling exercise in older individuals is beneficial for the cardiovascular system and quadriceps muscles, including partially reversing the age‐related loss of quadriceps muscle mass. However, the effect of cycling exercise on the numerous other lower limb muscles is unknown. Six older men (74 ± 8 years) underwent MRI before and after 12‐weeks of progressive aerobic cycle exercise training (3–4 days/week, 60–180 min/week, 60%–80% heart rate reserve,VO2max: +13%) for upper (rectus femoris, vastii, adductor longus, adductor magnus, gracilis, sartorius, biceps femoris long head, biceps femoris short head, semimembranosus, semitendinosus) and lower (anterior tibial, posterior tibialis, peroneals, flexor digitorum longus, lateral gastrocnemius, medial gastrocnemius, soleus) leg muscle volumes. In the upper leg, cycle exercise training induced hypertrophy (p ≤ 0.05) in the vastii (+7%) and sartorius (+6%), with a trend to increase biceps femoris short head (+5%,p = 0.1). Additionally, there was a trend to decrease muscle volume in the adductor longus (−6%,p = 0.1) and biceps femoris long head (−5%,p = 0.09). In the lower leg, all 7 muscle volumes assessed were unaltered pre‐ to post‐training (−2% to −3%,p > 0.05). This new evidence related to cycle exercise training in older individuals clarifies the specific upper leg muscles that are highly impacted, while revealing all the lower leg muscles do not appear responsive, in the context of muscle mass and sarcopenia. This study provides information for exercise program development in older individuals, suggesting other specific exercises are needed for the rectus femoris and adductors, certain hamstrings, and the anterior and posterior lower leg muscles to augment the beneficial effects of cycling exercise for older adults.
Statistical versus Economic Significance in Accounting: A Reality Check
Authors: Bertomeu Jeremy 
Published: August 2023

Abstract
Empirical research is ripe for a reality check, as elegantly put by the “elephants in the room” (Ohlson, 2025. Empirical accounting seminars: Elephants in the room. Accounting, Economics, and Law: Convivium
15, 1–8) referring to practices to disguise false positives with the aid of statistical engineering. However, the diagnosis points to a deeper problem. The dominant empirical paradigm combines extraordinarily vague hypotheses with ridiculously high desired levels of statistical confidence beatable solely with econometric hacks. Instead, I argue that economic magnitudes measure meaningful theoretical constructs and require far less than conventional significance levels for measurements of sufficient importance. Precisely estimating that an effect is close to zero can be more meaningful than a noisy but significant coefficient. I make several actionable proposals: (1) report standard errors rather than conventional statistical significance (stars) or t-stats, (2) discuss target significance levels likely to change priors and could much higher than weak significance for unsettled questions, (3) report precisely estimated zeros and power analyses, and (4) anchor empirical design on formal theory justified with precise references or structural models.
DUSP1 promotes pancreatic cancer cell proliferation and invasion by upregulating nephronectin expression
Authors: Chen Yanlin , Ma Yunfei , Tang Yuting , Jin Yucui , Zhu Yi , Ma Changyan 
Published: August 2023

Abstract

Objectives
To explore the role of dual-specific phosphatase 1 (DUSP1) in the proliferation, migration and invasion of pancreatic cancer (PC).

Methods
TCGA and GTEx databases were used to investigate the relationship between DUSP1 expression and prognosis of PC patients. Expression efficiency of DUSP1 was validated by qPCR and western blotting. The proliferation of SW1990 and PANC-1 cells with DUSP1 overexpression or knockout was detected by EdU assays. The migratory and invasive abilities of cells were detected by wound healing and transwell assays.

Results
DUSP1 was highly expressed in PC and associated with poor prognosis of patients. Overexpression of DUSP1 promoted the proliferation, migration and invasion of PC cells by regulating nephronectin (NPNT), whereas knockout of DUSP1 exhibited the opposite effects. NPNT expression was positively correlated with DUSP1, and the overall survival of PC patients with high levels of NPNT was shorter.

Conclusions
DUSP1 promoted the proliferation, migration and invasion of PC cells by upregulating NPNT, suggesting DUSP1 may be a potential target for PC treatment.
A vezetői szerepek és a vezetés szükségszerűségének vizsgálati lehetősége
Authors: Márta Erik 
Published: August 2023

A TANULMÁNY CÉLJA
A vezetés és a vezetői tevékenység kiemelt fontosságú a csoportok és szervezetek működésében. A tanulmány az alapul szolgáló elvárásokból kialakult vezetés szükségszerűségét elemzi, majd az abból eredő szerepeket fejti ki, amelyek szükségesek az eredményes és hatékony vezetői tevékenységhez. Továbbá ezen elvárások összekapcsolása történik a vezetői szerepek kialakulásával, annak érdekében, hogy a vezetés, mint a közös tevékenységek természetéből adódó szükségszerűségét igazolja.
ALKALMAZOTT MÓDSZERTAN
A vezetés szükségszerűségét bemutató, átfogó szakirodalmi források feldolgozásával vizsgálom a vezetőkkel szemben támasztott legfontosabb és legáltalánosabb elvárásokat, valamint ismertetem a vezetői szerepek jellegét és okait is.
Azokat a forrásokat mutatom be, amelyek tartalma elvárásokként fogalmazhatók meg a vezetők magatartására és viselkedésére vonatkozóan. Ezt követően a mintzbergi (1975) szereptipológiából kiindulva vizsgálom annak aktualitását napjaink gazdasági szervezeteiben. Az elvégzett kutatás során feltárom, hogy a XXI. századi gazdasági szervezetekben mely vezetői szerepek figyelhetők meg leginkább, és melyek teljesülésére irányulnak a legnagyobb elvárások.
LEGFONTOSABB EREDMÉNYEK
A vezetés a társadalmi és gazdasági folyamatok realizálásának a feltétele. Ennek során különböző elvárások fogalmazódnak meg a vezetők felé, melyek teljesülése esetén válhat valaki alkalmassá a pozíció betöltésére. A különböző vezetői szerepek az elvárásokon keresztül vizsgálhatók, ugyanis a vezetők alkalmassága a vezetői szerepeknek való megfelelésként is értelmezhető.
A mintzbergi (1975) szereptipológiából kiindulva, szakirodalmi források feldolgozásával megállapítottam, hogy a gazdasági szervezetek olyan jelentős átalakulásokon mennek keresztül, melyek hatnak a különböző elvárásokra, illetve az abból kialakuló vezetői szerepekre is.
GYAKORLATI JAVASLATOK
A kutatás eredményei hozzájárulhatnak a vezetői tevékenységek mélyebb megismeréséhez, és akár messzemenő következtetések levonását is megalapozhatja. A vezetéssel/vezetőkkel szemben támasztott elvárások alaposabb ismerete pedig a csoportok fenntarthatóságát és fejlődését eredményezheti.
NMDA Receptors in the Basolateral Amygdala Complex Are Engaged for Pavlovian Fear Conditioning When an Animal’s Predictions about Danger Are in Error
Authors: Keidar Tuval , Williams-Spooner Matthew J. , Wong Francesca S. , Westbrook R. Frederick , Holmes Nathan M. 
Published: August 2023

It is widely accepted that Pavlovian fear conditioning requires activation of NMDA receptors (NMDARs) in the basolateral amygdala complex (BLA). However, it was recently shown that activation of NMDAR in the BLA is only required for fear conditioning when danger occurs unexpectedly; it is not required for fear conditioning when danger occurs as expected. This study tested the hypothesis that NMDARs in the BLA are engaged for Pavlovian fear conditioning when an animal’s predictions regarding danger are in error. In each experiment, rats (females in Experiment 1 and males in Experiments 2–5) were conditioned to fear one stimulus, S1, when it was paired with foot-shock (S1→shock), and 48 h later, a second stimulus, S2, when it was presented in sequence with the already-conditioned S1 and foot-shock (S2→S1→shock). Conditioning to S2 occurred under a BLA infusion of the NMDAR antagonist, D-AP5 or vehicle. The subsequent tests of freezing to S2 alone and S1 alone revealed that the antagonist had no effect on conditioning to S2 when the shock occurred exactly as predicted by the S1, but disrupted this conditioning when the shock occurred earlier/later than predicted by S1, or at a stronger/weaker intensity. These results imply that errors in the timing or intensity of a predicted foot-shock engage NMDARs in the BLA for Pavlovian fear conditioning. They are discussed in relation to theories which propose a role for prediction error in determining how experiences are organized in memory and how activation of NMDAR in the BLA might contribute to this organization.SIGNIFICANCE STATEMENTThis study is significant in showing that prediction error determines how a new experience is encoded with respect to a past experience and, thereby, whether NMDA receptors (NMDARs) in the basolateral amygdala complex (BLA) encode the new experience. When prediction error is small (e.g., danger occurs as and when expected), the new experience is encoded together with a past experience as part of the same “mental model,” and NMDAR activation in the BLA is not needed for this encoding. By contrast, when prediction error is large (e.g., danger occurs at an unexpected intensity or time), the new experience is encoded separately from the past experience as part of a new mental model, and NMDAR activation in the BLA is needed for this encoding.
Speech Reception in Young Children with Autism Is Selectively Indexed by a Neural Oscillation Coupling Anomaly
Authors: Wang Xiaoyue , Delgado Jaime , Marchesotti Silvia , Kojovic Nada , Sperdin Holger Franz , Rihs Tonia A. , Schaer Marie , Giraud Anne-Lise 
Published: August 2023

Communication difficulties are one of the core criteria in diagnosing autism spectrum disorder (ASD), and are often characterized by speech reception difficulties, whose biological underpinnings are not yet identified. This deficit could denote atypical neuronal ensemble activity, as reflected by neural oscillations. Atypical cross-frequency oscillation coupling, in particular, could disrupt the joint tracking and prediction of dynamic acoustic stimuli, a dual process that is essential for speech comprehension. Whether such oscillatory anomalies already exist in very young children with ASD, and with what specificity they relate to individual language reception capacity is unknown. We collected neural activity data using electroencephalography (EEG) in 64 very young children with and without ASD (mean age 3; 17 females, 47 males) while they were exposed to naturalistic-continuous speech. EEG power of frequency bands typically associated with phrase-level chunking (δ, 1–3 Hz), phonemic encoding (low-γ, 25–35 Hz), and top-down control (β, 12–20 Hz) were markedly reduced in ASD relative to typically developing (TD) children. Speech neural tracking by δ and θ (4–8 Hz) oscillations was also weaker in ASD compared with TD children. After controlling gaze-pattern differences, we found that the classical θ/γ coupling was replaced by an atypical β/γ coupling in children with ASD. This anomaly was the single most specific predictor of individual speech reception difficulties in ASD children. These findings suggest that early interventions (e.g., neurostimulation) targeting the disruption of β/γ coupling and the upregulation of θ/γ coupling could improve speech processing coordination in young children with ASD and help them engage in oral interactions.SIGNIFICANCE STATEMENTVery young children already present marked alterations of neural oscillatory activity in response to natural speech at the time of autism spectrum disorder (ASD) diagnosis. Hierarchical processing of phonemic-range and syllabic-range information (θ/γ coupling) is disrupted in ASD children. Abnormal bottom-up (low-γ) and top-down (low-β) coordination specifically predicts speech reception deficits in very young ASD children, and no other cognitive deficit.
Bedingungsloses Grundeinkommen und Solidarisches Bürgergeld – mehr als sozialutopische Konzepte
Authors: Hohenleitner Ingrid , Opielka Michael , Schramm Michael 
Published: August 2023

Thomas Straubhaar und Ingrid Hohenleitner skizzieren das Modell eines bedingungslos gewährten Grundeinkommens. Sie zeigen, dass es auch für Deutschland finanzierbar ist. Sie sehen im Grundeinkommen die Chance, den Staatshaushalt nachhaltig zu sanieren und den Sozialstaat auch für künftige Generationen wieder finanzierbar zu machen. Sie zeigen, dass insbesondere im Niedriglohnbereich neue Arbeitsplätze im Umfang von bis zu 1,17 Millionen Vollzeitstellen geschaffen werden könnten.
Michael Opielka sieht im Modell von Althaus „eine Art Kombilohn für alle“. Ein Teil des Volkseinkommens werde auf alle verteilt. Mit einer „Mischung aus Pragmatismus und Idealismus“ schaffe das Solidarische Bürgergeld einerseits einen „echten“ Arbeitsmarkt, mache zugleich aber Teilzeitarbeit lohnend und sichere freiwilliges Engagement und Bildungsphasen ab. Mit dem Solidarischen Bürgergeld führe die Lohndifferenzierung im unteren Einkommensbereich nicht mehr zu Armut.
Das Solidarische Bürgergeld von Dieter Althaus wäre ein wichtiger Schritt auf dem Wege zu mehr gesellschaftlicher Solidarität, zu mehr Subsidarität und zu mehr (sozialer) Gerechtigkeit. Zu diesem Fazit kommt Michael Schramm. Zudem würde das System der sozialen Sicherung auf eine ökonomisch tragfähige Basis gestellt und eine Belebung des Arbeitsmarktes sowie der unternehmerischen Kräfte bewirkt.
Lithography-based additive manufacturing of ceramics: Materials, applications and perspectives
Authors: Stampfl Jürgen , Schwentenwein Martin , Homa Johannes , Prinz Fritz B. 
Published: August 2023

AbstractLithography-based additive manufacturing methods emerged as a powerful method for manufacturing of complex-shaped ceramic parts with excellent functional and structural properties. This paper summarizes the current state of the art in this field by articulating technological challenges associated with printing of functional parts. In addition, the paper addresses process requirements towards further enhancing component quality. A key aspect for obtaining high-quality parts is related to controlling chemical composition and uniformity of the photopolymerizable slurries. The latter requires in-depth understanding of the underlying photochemical processes. Changes in the formulation of the resin as well as changes in the exposure strategy distinctly influence bond conversion and gelling, which, in turn, influence the properties of the green part during thermal processing. Properly optimized processes and material composition allow to target a variety of challenging applications including patient specific parts for digital dentistry, and 3D-printed ceramics which can operate in harsh environments, as may be required in aerospace or chemical engineering applications. The paper will also provide an outlook into novel opportunities for 3D-printed ceramics.
Graphical abstract
Dynamics of functionally graded beams carrying a moving load with influence of porosities and partial foundation support
Authors: Vu Thi An Ninh  
Published: August 2023

The novelty of the present work is to study the simultaneous influence of porosities and partial Pasternak foundation support on dynamics of functionally graded (FG) beams carrying a moving load. The beams are made from an open-cell steel foam with symmetric and asymmetric porosity distributions in the thickness direction. Based on a refined third-order shear deformation theory, a two-node beam element with ten degrees of freedom is derived and employed to construct the discretized equation of motion for the beams. Dynamic characteristics, including the time histories for mid-span deflection, dynamic magnification factor (DMF) and the stress distribution, are computed with the aid of the Newmark method. The numerical result reveals that the foundation supporting length has an important role on the dynamics of the beams, and the dependence of the DMF upon the porosity coefficient is governed by the foundation supporting length. It is also found that the asymmetric porosity distribution has more impact on the dynamic response of the beams than the symmetric one does, and the difference between the DMFs obtained from the two porosity distributions is more significant for the beam with a higher porosity coefficient. The effects of the porosities, the foundation support and the moving load velocity on the dynamic behavior of the beams are examined in detail and highlighted
Does prosody contribute to the expression of the dialogism of the utterance?
Authors: Nowakowska Alexandra 
Published: August 2023

Within the framework of utterance production theories “à la française”, different approaches of enunciative heterogeneity have been developed since the end of the 1970’s in interaction, re-work, and re-appropriation of notions of polyphony and dialogism borrowed from the Bakhtin Circle. These approaches, beyond their differences, have had little interest in prosodic, vocal and gestural dimensions of the discursive units under study.It is this “omission” which the present article intends to break by analyzing a political interview. We study the way in which the observed syntactic and rhetorical dialogic markers - direct speech, cleft sentence and pseudo-cleft sentence, negation, parallelism, echo and autonymous modalization - are or are not marked prosodically and vocally.
Upcycling of demolition material from concrete and brick for the production of cold-bound, alkali-activated lightweight aggregates
Authors: Wichmann Isabelle , Firdous Rafia , Stephan Dietmar 
Published: August 2023

AbstractThis paper deals with the production of artificial aggregates based on the recycled fine fraction (≤ 4 mm) from construction demolition waste. Concrete powder, brick powder and their combination were used to produce aggregates through pelletisation using sodium silicate solution as an activator. For all aggregates, efficiency, bulk crushing resistance, particle density, water absorption and loose bulk density were evaluated. The bulk crushing resistance was evaluated for samples cured with different methods. A higher proportion of concrete powder increased the strength and density. The aggregates were successfully formed with bulk crushing resistance and particle densities in the range of lightweight aggregates.
Graphical abstract
Traducción y enseñanza / aprendizaje de LE: enfoques posibles
Authors: Romanelli Sergio , Guimarães Soares Noêmia 
Published: August 2023

El presente artículo tiene como objeto presentar y discutir algunas ideas referentes al binomio traducción/enseñanza y aprendizaje de LE, en el sentido de reconocer la aproximación entre estos dos temas. Tal idea surgió a partir de una profunda reflexión sobre la experiencia vivida en el marco de un curso denominado Traducción y aprendizaje de lenguas extranjeras, dictado por los autores de este artículo, en el posgrado de Traductología (PGET por sus siglas en portugués) de la Universidad Federal de Santa Catarina (UFSC). Se puede observar que se examinaron muchos puntos referentes a la práctica efectiva de alumnos y docentes de enseñanza de LE, por medio de cuestiones que giraban en torno al tema de traducción. De esta manera, teniendo a la traducción como centro de discusión y con base en teóricos como Atkinson (1993), Malmkjaer (1998) y Balboni (2002), se retomaron y redimensionaron asuntos importantes, tales como conceptos de lengua y traducción, relación entre docente y aprendiz, papel del aprendiz en la enseñanza (sus expectativas), relación entre LM y LE, uso de diccionarios, tipologías textuales, etc. Para los egresados de los cursos de Lenguas Extranjeras fue de vital importancia que se hayan retomado las cuestiones referentes a la enseñanza y el aprendizaje de LE; pues muchos de ellos, después de su primera formación, no habían tenido la oportunidad de revisar teóricamente o de rediscutir su práctica ya como docentes profesionales. Además, el intercambio de experiencias en torno a los temas de traducción y enseñanza de lenguas fue bastante enriquecedor tanto para los estudiantes como para los docentes de la disciplina, pues se ponían sobre la mesa experiencias muy diversas: estudiantes y docentes de varias lenguas extranjeras diferentes, educación pública, educación privada, cursos privados de lenguas, experiencias a niveles principiante, medio y avanzado, entra otras.
El uso del software de transcripción lingüística ELAN en el análisis de la interpretación de lengua de señas colombiana en el contexto universitario
Authors: Barreto Muñoz Alex Giovanny , Amores Heredia Sonia Margarita 
Published: August 2023

La Universidad Pedagógica Nacional en el marco del proyecto Manos y Pensamiento ha contratado y gestionado la prestación del servicio de interpretación de lengua de señas colombiana - español, como parte de la estrategia para facilitar la inclusión de estudiantes Sordos a la vida universitaria. Una de las Mesas de Investigación generadas al interior del equipo de intérpretes de la Universidad, ha explorado la posibilidad de usar el software ELAN como herramienta para analizar la interpretación en el contexto universitario. En el presente artículo, se presentan los resultados del proyecto piloto propuesto por la Mesa ELAN y se esbozan algunas potencialidades y proyecciones que pudiera tener un proyecto de investigación de la lengua de señas y su interpretación al interior de la Universidad utilizando dicho software.
romance, dos traducciones: tras la huella de Oliver Twist
Authors: Camelo Franciano 
Published: August 2023

En 1870, atendiendo a la invitación de los propietarios del Jornal da Tarde, Machado de Assis tradujo parte de la novela de Charles Dickens Oliver Twist. Es importante señalar que la traducción de la novela de Dickens en el contexto brasileño del siglo XIX no se hizo directamente del inglés hacia el portugués, sino vía una traducción francesa. De hecho, el recorrido de la novela de Dickens implica una red de publicaciones, ediciones y traducciones en la que Francia jugó el papel de intermediaria. Este artículo presenta el recorrido de la novela de Dickens desde Inglaterra hasta Brasil, considerando particularidades (con)textuales de la novela inglesa y de las traducciones francesa y machadiana.
La integración del tema transversal en la enseñanza de la documentación para traductores
Authors: Márquez Melva Josefina 
Published: August 2023

El presente estudio se enfoca en la enseñanza de la documentación (digital, primordialmente) para la traducción. Se toma el concepto de transversalidad desde el lado que entreteje ámbitos temáticos tomados como soportes del desarrollo de la competencia documental del futuro traductor y no del lado más común, esto es, como "temas educativos que responden a determinados problemas sociales y que están presentes en el conjunto de las áreas curriculares" (Muñoz de LaCalle, 1997). La competencia documental, esencial en el traductor, es definida como "el manejo adecuado de técnicas de organización, procesamiento y recuperación de la información" (Pinto 1999). Como el traductor ha de tener presente los objetivos y funciones de la traducción, la adecuación textual y terminológica y las necesidades de sus clientes, se hace imprescindible su alfabetización informacional (Pinto Molina 2005 en Sales 2006). En ello la transversalidad juega un papel importante en la enseñanza de la documentación a futuros traductores. Por tal motivo, en este estudio se describe la experiencia pedagógica de varias ediciones del curso de Documentación y Terminología para traductores en el programa de licenciatura en Idiomas Modernos de la Universidad de Los Andes (Venezuela). Se proponen objetivos y temas que pudieran ser considerados para cursos similares.