bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efficacy of different bowel preparation regimen volumes for colorectal cancer screening and compliance with European Society of Gastrointestinal Endoscopy performance measures
Authors: Theunissen Felix , Lantinga Marten Alexander , ter Borg Pieter C. J. , Ouwendijk Rob J. T. , Siersema Peter D. , Bruno Marco J. ,   the Trans. IT foundation study group
Published: May 2023

AbstractBackgroundVarious volumes of bowel preparation are used in clinical practice. There is conflicting data on the effectiveness of individual regimens. This study aims to evaluate the efficacy and compliance of currently used bowel preparations with the European Society of Gastrointestinal Endoscopy (ESGE) performance measures using data of the Dutch nationwide colorectal cancer screening (CRC) program.MethodsIn a prospective, multicenter endoscopy database, we identified all CRC screening colonoscopies performed in 15 Dutch endoscopy centers from 2016 to 2020. We excluded procedures without documented bowel preparation or the Boston Bowel Preparation Scale (BBPS) score. Bowel preparation regimens were categorized into three groups, that is, 4‐L (polyethylene glycol (PEG)), 2‐L (2‐L PEG with ascorbic acid) and ≤1‐L volumes (sodium picosulfate with magnesium citrate, 1L‐PEG with sodium sulfate and ascorbic acid or oral sulfate solution). European Society of Gastrointestinal Endoscopy performance measures included adequate BBPS score (≥6) (>90%), cecal intubation rate (CIR, >90%), adenoma detection rate (ADR, >25%) and polyp detection rate (PDR, >40%). Logistic regression was performed to identify predictive factors for adequate BBPS and patient discomfort.ResultsA total of 39,042 CRC screening colonoscopies were included. Boston Bowel Preparation Scale scores, CIR, ADR and PDR for 4L, 2L and ≤1L regimens all met the minimum ESGE performance measures standards. However, an adequate BBPS score was more frequently seen with 2L regimens (98.0%) as compared to 4L (97.1%) and ≤1L regimens (97.0%) (p < 0.001), respectively. In addition, CIR was higher for ≤1L (98.4%) versus 4L (97.7%) and 2L (97.9%) regimens (p = 0.001), ADR higher for lower volume (≤1L (60.0%) and 2L (61.2)) versus higher volume (4L (58.6%)) regimens (p < 0.001), and PDR higher for ≤1L (70.0%) and 2L (70.8%) versus 4L (67.2%) regimens (p < 0.001). Boston Bowel Preparation Scale for ≤1L regimens was higher when combined with bisacodyl (97.3%) than without (95.6%) (p < 0.001). Overall, bisacodyl use was independently associated with higher patient discomfort (odds ratios = 1.47, confidence intervals = 1.26–1.72).ConclusionsDespite variations in bowel preparation volumes, all regimens meet the minimum ESGE performance measures for bowel preparation and other quality parameters. Boston Bowel Preparation Scale can be further improved if ultra low volume regimens are combined with bisacodyl. The choice for either bowel preparation volume can therefore be based on volume‐tolerance and patient preference.
Prevalence and detection rate of major congenital heart disease in twin pregnancies in Denmark
Authors: Bouazzi M. , Jørgensen D. E. S. , Andersen H. , Krusenstjerna‐Hafstrøm T. , Ekelund C. K. , Jensen A. N. , Sandager P. , Sperling L. , Steensberg J. , Sundberg K. , Vejlstrup N. G. , Petersen O. B. B. , Vedel C. 
Published: May 2023

ABSTRACTObjectiveTo investigate the national prevalence and prenatal detection rate (DR) of major congenital heart disease (mCHD) in twin pregnancies without twin‐to‐twin transfusion syndrome (TTTS)‐associated CHD in a Danish population following a standardized prenatal screening program.MethodsThis was a national registry‐based study of data collected prospectively over a 10‐year period. In Denmark, all women with a twin pregnancy are offered standardized screening and surveillance programs in addition to first‐ and second‐trimester screening for aneuploidies and malformation, respectively: monochorionic (MC) twins every 2 weeks from gestational week 15 and dichorionic (DC) twins every 4 weeks from week 18. The data were retrieved from the Danish Fetal Medicine Database and included all twin pregnancies from 2009–2018, in which at least one fetus had a pre‐ and/or postnatal mCHD diagnosis. mCHD was defined as CHD requiring surgery within the first year of life, excluding ventricular septal defects. All pregnancy data were pre‐ and postnatally validated in the local patient files at the four tertiary centers covering the entire country.ResultsA total of 60 cases from 59 twin pregnancies were included. The prevalence of mCHD was 4.6 (95% CI, 3.5–6.0) per 1000 twin pregnancies (1.9 (95% CI, 1.3–2.5) per 1000 live births). The prevalences for DC and MC were 3.6 (95% CI, 2.6–5.0) and 9.2 (95% CI, 5.8–13.7) per 1000 twin pregnancies, respectively. The national prenatal DR of mCHD in twin pregnancies for the entire period was 68.3%. The highest DRs were in cases with univentricular hearts (100%) and the lowest with aortopulmonary window, total anomalous pulmonary venous return, Ebstein's anomaly, aortic valve stenosis and coarctation of the aorta (0–25%). Mothers of children with prenatally undetected mCHD had a significantly higher body mass index (BMI) compared to mothers of children with a prenatally detected mCHD (median, 27 kg/m2 and 23 kg/m2, respectively; P = 0.02).ConclusionsThe prevalence of mCHD in twins was 4.6 per 1000 pregnancies and was higher in MC than DC pregnancies. The prenatal DR of mCHD in twin pregnancies was 68.3%. Maternal BMI was higher in cases of prenatally undetected mCHD. © 2023 The Authors. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.
Pericarditis caused by Proteus mirabilis in sheep
Authors: Najd Ghahremani Abolfazl , Abdollahi Mostafa , Shokrpoor Sara , Ashrafi Tamai Iraj 
Published: May 2023

AbstractPericarditis means inflammation in the pericardial sac. Pericarditis is divided into three categories based on morphology, including fibrinous, purulent, and constrictive. In the present study, a 7‐month‐old male Ghezel breed sheep was examined for low weighting rate for three months. Tachypnea, tachycardia, heart friction sound, absence of fever and normal appetite were recorded in the clinical examination. In the patient's history, there was a history of perforated chest trauma behind the left scapula about three months ago. After the echocardiography examination and bacteriology procedures, purulent pericarditis caused by Proteus mirabilis was diagnosed. The bacterium was analysed using genome sequencing and new strain called Abhar114 was diagnosed. This is the first report of pericarditis caused by Proteus mirabilis in sheep.
Holographic thermal propagator for arbitrary scale dimensions
Authors: Bajc Borut , Lugo Adrián R. 
Published: May 2023

Abstract
Using the AdS/CFT correspondence we model the behaviour of the two-point correlator of an operator with arbitrary scale dimension ∆ in arbitrary spacetime dimension d for small but non-zero temperature. The obtained propagator coincides in the low temperature regime with the known result for d = 4 for large ∆ at the order Td as well as with the Td and T2d terms of the exact all order result for d = 2. Furthermore, for arbitrary d we explicitly write down the expression for the order Td of the propagator for arbitrary ∆, and present a conjecture for the order T2d in the large ∆ limit.
Exploring Higgs-photon production at the LHC
Authors: Biswas Tisa , Datta Anindya 
Published: May 2023

Abstract
We have investigated the signal for physics beyond the Standard Model via Higgs plus photon final state, hitherto unobserved at the LHC, in the framework of Standard Model Effective Field Theory. Using the relevant dimension-6 operators, we probe two distinct classes of interactions, based on the Lorentz structure of Higgs couplings to gauge bosons and fermions. To begin with, constraints on the Wilson coefficients of these operators have been derived from existing experimental data. We then focus on the hadronic decay of the Higgs boson to two bottom quarks in the boosted regime, leading to a high pT fat-jet recoiling against a hard photon. Following a CMS Run II search for a heavy resonance decaying into a Higgs boson and a photon, a detailed signal and background analysis for this channel has been done and limits on the relevant Wilson coefficients have been obtained. By performing a cut-based analysis, we identify some kinematic observables that distinguish between signal and SM background. Minimum values of the Wilson coefficients that will yield 3σ signal significance at the 14 TeV run of the LHC with 3000 fb−1 data, have been obtained. A multivariate analysis using a boosted decision tree and exploiting the jet substructure techniques further help to isolate the regions of phase space where the contribution of SMEFT driven signal is significantly enhanced. Finally, we briefly discuss the parameter dependencies and interpretations of the allowed values of the coefficients on a particularly interesting UV complete model namely, the Minimal Supersymmetric Standard Model.
RG flows and stability in defect field theories
Authors: Carreño Bolla I. , Rodriguez-Gomez D. , Russo J. G. 
Published: May 2023

Abstract
We investigate defects in scalar field theories in four and six dimensions in a double-scaling (semiclassical) limit, where bulk loops are suppressed and quantum effects come from the defect coupling. We compute β-functions up to four loops and find that fixed points satisfy dimensional disentanglement — i.e. their dependence on the space dimension is factorized from the coupling dependence — and discuss some physical implications. We also give an alternative derivation of the β functions by computing systematic logarithmic corrections to the Coulomb potential. In this natural scheme, β functions turn out to be a gradient of a ‘Hamiltonian’ function $$ \mathcal{H} $$
H
. We also obtain closed formulas for the dimension of scalar operators and show that instabilities do not occur for potentials bounded from below. The same formulas are reproduced using Rigid Holography.
Lepton-flavoured scalar dark matter in Dark Minimal Flavour Violation
Authors: Acaroğlu Harun , Agrawal Prateek , Blanke Monika 
Published: May 2023

Abstract
We study a simplified model of lepton-flavoured complex scalar dark matter set up in the Dark Minimal Flavour Violation framework. In this model the Standard Model is extended by a scalar dark matter flavour triplet and a charged fermionic mediator, through which dark matter couples to the right-handed charged leptons of the Standard Model. This interaction is parameterized by a new 3 × 3 coupling matrix λ. Consistent with the field content of the model, also the Standard Model’s approximate flavour symmetry is extended to include an additional global U(3) associated with the dark matter flavour triplet. In addition to the Standard Model Yukawa couplings, the new coupling matrix λ is assumed to constitute the only source that violates this extended symmetry. We analyse the parameter space of this model by investigating constraints from collider searches, lepton flavour violating decays, the observed dark matter relic density, and direct as well as indirect dark matter detection experiments. By performing a combined analysis of all constraints we find that restrictions from lepton flavour violating decays, the observed relic density and dark matter nucleon scattering are dominant. The combination of the latter two renders limits from collider searches irrelevant while indirect detection constraints are weak due to a p-wave suppression of the annihilation rate. We conclude that lepton-flavoured scalar dark matter has a rich phenomenology and is a viable dark matter candidate.
Toward random tensor networks and holographic codes in CFT
Authors: Chandra Jeevan , Hartman Thomas 
Published: May 2023

Abstract
In holographic CFTs satisfying eigenstate thermalization, there is a regime where the operator product expansion can be approximated by a random tensor network. The geometry of the tensor network corresponds to a spatial slice in the holographic dual, with the tensors discretizing the radial direction. In spherically symmetric states in any dimension and more general states in 2d CFT, this leads to a holographic error-correcting code, defined in terms of OPE data, that can be systematically corrected beyond the random tensor approximation. The code is shown to be isometric for light operators outside the horizon, and non-isometric inside, as expected from general arguments about bulk reconstruction. The transition at the horizon occurs due to a subtle breakdown of the Virasoro identity block approximation in states with a complex interior.
TCFHs, IIB warped AdS backgrounds and hidden symmetries
Authors: Grimanellis L. , Papadopoulos G. 
Published: May 2023

Abstract
We present the twisted covariant form hierarchies (TCFHs) on the internal spaces of all type IIB warped AdS backgrounds. As a result we demonstrate that the form bilinears on the internal spaces satisfy a generalisation of the conformal Killing-Yano equation. We also explore some of the properties of the TCFHs, like for example the holonomy of the TCFH connections. In addition, we present examples where the form bilinears generate hidden symmetries for particle probes propagating on the internal spaces of some AdS backgrounds. These include the maximally supersymmetric AdS5 solution as well as some of the near horizon geometries of intersecting IIB branes.
Nanoarchitectonics of ethylene propylene diene monomer (EPDM) composites reinforced with Cu–Al–Zn-alloy for ultrasonic array transducers’ fabrication
Authors: Barakat Mirham A. Y. , El-Sabbagh Salwa H. , Mohamed Wael S. , Mahmoud Doaa S. 
Published: May 2023

AbstractIn response to the continuous demand for industry progress and the need for low-cost alternative materials that have superior properties than the present ones, a new coupling agent was used to treat composites, which were used as new backing materials in ultrasonic array transducers. In array transducers, back-echo reverberation to the piezoelectric elements occurs, so backing materials are critical in reducing these echoes. The Cu–Al–Zn-alloy was treated with a coupling agent before being incorporated into ethylene propylene diene monomer (EPDM) composites. Cu–Al–Zn-alloy/EPDM composites were assessed using rheometric, mechanical, and morphological properties. The division of cu-alloy at the EPDM matrix was visualized using a scanning electron microscope (SEM). TGA and DSC techniques were used to study the thermal characterization of the EPDM composites. As a result, the treated Cu-alloy improved the thermal, mechanical, and morphological characteristics of EPDM composites. Ultrasonic measurements ensured the composites' effectiveness as backing materials in ultrasonic array transducers. Furthermore, the composites’ properties were similar to those of the most commonly used epoxy/tungsten backing material. Finally, linear ultrasonic-phased array transducers were fabricated using Cu–Al–Zn-alloy/EPDM composites. They had a low signal-to-noise ratio, and this ensured the effectiveness of Cu–Al–Zn-alloy/EPDM composites as backing materials.
A novel risk prediction nomogram for early death in patients with resected synchronous multiple primary colorectal cancer based on the SEER database
Authors: Zhang Xiangyu , Zhao Liang , Hu Yanpeng , Deng Kai , Ren Wanbo 
Published: May 2023

Abstract
Background
Synchronous multiple primary colorectal cancer (SMPCC) involves the simultaneous occurrence of 2 or more independent primary malignant tumors in the colon or rectum. Although SMPCC is rare, it results in a higher incidence of postoperative complications and mortality compared to patients with single primary colorectal cancer (SPCRC).

Methods
The clinical factors and survival outcomes of SMPCC patients registered on the Surveillance, Epidemiology, and End Results (SEER) database between 2000 and 2017 were extracted. The patients were divided into the training and validation cohorts using a ratio of 7:3. Univariate and multivariate logistic regression analyses were used to identify the independent risk factors for early death. The performance of the nomogram was evaluated using the concordance index (C-index), calibration curves, and the area under the curve (AUC) of a receiver operating characteristics curve (ROC). A decision curve analysis (DCA) was used to evaluate the clinical utility of the nomogram and standard TNM system.

Results
A total of 4386 SMPCC patients were enrolled in the study and randomly assigned to the training (n = 3070) and validation (n = 1316) cohorts. The multivariate logistic analysis identified age, chemotherapy, radiotherapy, T stage, N stage, and M stage as independent risk factors for all-cause and cancer-specific early death. The marital status was associated with all-cause early death, and the tumor grade was associated with cancer-specific early death. In the training cohort, the nomogram achieved a C-index of 0.808 (95% CI, 0.784–0.832) and 0.843 (95% CI, 0.816–0.870) for all-cause and cancer-specific early death, respectively. Following validation, the C-index was 0.797 (95% CI, 0.758–0.837) for all-cause early death and 0.832 (95% CI, 0.789–0.875) for cancer-specific early death. The ROC and calibration curves indicated that the model had good stability and reliability. The DCA showed that the nomogram had a better clinical net value than the TNM staging system.

Conclusion
Our nomogram can provide a simple and accurate tool for clinicians to predict the risk of early death in SMPCC patients undergoing surgery and could be used to optimize the treatment according to the patient's needs.
Multiskaliger Ansatz zur Lebensdauerabschätzung von Wälzlagern mit Hilfe des lokalen Ermüdungsmodells nach Fatemi-Socie
Authors: Foko Foko Flavien , Rüth Lukas , Koch Oliver , Sauer Bernd 
Published: May 2023

ZusammenfassungEin multiskaliger Ansatz zur Lebensdauerabschätzung von Wälzlagern wird vorgestellt und auf Innenringe von Zylinderrollenlagern des Typs NU 1006 angewendet. Aus einer Systemmodellierung auf der Makroebene werden die im Wälzkontakt wirkenden Kräfte bestimmt. Die mikroskaligen Kontaktsimulationen erfolgen in einem Halbraum-Kontaktmodell. Die Spannungen auf dem Innenring werden unter Berücksichtigung der plastischen Deformationen bestimmt und in den lokalen Ermüdungsansatz nach Fatemi-Socie zur Lebensdauerabschätzung eingesetzt. Drei Lastfälle: 3,8, 3,5 und 2,5 GPa als maximale Pressung im Kontakt Wälzkörper-Innenring werden dabei simulativ untersucht. Die simulierten und experimentell ermittelten Eigenspannungen und Ermüdungslebensdauern zeigen eine gute Übereinstimmung.
Immersive and desktop virtual reality in virtual fashion stores: a comparison between shopping experiences
Authors: Ricci Marina , Evangelista Alessandro , Di Roma Annalisa , Fiorentino Michele 
Published: May 2023

AbstractWith the high growth and prosperity of e-commerce, the retail industry needs to explore new technologies that improve digital shopping experiences. In the current technological scenario, Virtual Reality (VR) emerges as a tool and an opportunity for enhancing shopping activities, especially for the fashion industry. This study explores whether using Immersive Virtual Reality (IVR) technologies enhances the shopping experience in the fashion industry compared to Desktop Virtual Reality (DVR). A within-subject experiment was carried out involving a sample of 60 participants who completed a simulated shopping experience. In the first mode (DVR), a desktop computer setup was used to test the shopping experience using a mouse and keyboard for navigation. The second mode (IVR) exploited a Head-Mounted Display (HMD), and controllers, that allowed navigation while seated on a workstation to avoid sickness. Participants had to find a bag in the virtual shop and explore its features until they were ready to purchase it. Post-hoc measures of time duration of the shopping experience, hedonic and utilitarian values, user experience, and cognitive load were compared. Results showed that participants experienced higher hedonism and utilitarianism in the IVR shop compared to DVR. The cognitive load was comparable in both modes, while user experience was higher in IVR. In addition, the time duration of the shopping experience was higher in IVR, where users stayed immersed and enjoyed it for longer. This study has implications for fashion industry research, as the use of IVR can potentially lead to novel shopping patterns by enhancing the shopping experience.
A Particularist Approach to Arguments by Analogy
Authors: Alhambra José 
Published: May 2023

AbstractIn this article I defend what I call a ‘particularist approach to arguments by analogy.’ Particularism is opposed to generalism, which is the thesis that arguments by analogy require a universal principle that covers cases compared and guarantees the conclusion. Particularism rejects this claim and holds that arguments by analogy operate on particular cases. I elaborate on two ideas that support this position. On the one hand, I contend that an analogy can be seen as a parallelism of argumentative relationships, drawing on the distinction between similarity and analogy (Gentner 1983) and on the meta-argumentative account of arguments by analogy (Woods and Hudak 1989). On the other hand, I argue that universal principles are not necessary neither for the analysis nor the evaluation of arguments by analogy (Govier 1989) and that, rather than being a requirement, they can be seen as by-products of good analogies.
A multi-level modeling approach to guide management of female feral hogs in Great Smoky Mountains National Park
Authors: Buderman Frances E. , Helm Patrick J. , Clark Joseph D. , Williamson Ryan H. , Yarkovich Joseph , Mullinax Jennifer M. 
Published: May 2023

AbstractWe trapped, anesthetized, and fit 16 female feral swine (Sus scrofa) with Global Positioning System (GPS) collars in Great Smoky Mountains National Park (GRSM) to develop predictive summer and winter models for more effective population control efforts. Given the highly diverse habitat and topography in GRSM and the spatial extent of our dataset, we employed Step Selection Function (SSF) to evaluate resource selection at the 3rd-order level and Resource Selection Function (RSF) models at the 2nd-order level for both summer and winter seasons. The summer SSF and RSF models suggested relatively similar levels of selection, whereas the winter models differed by method. We created a straightforward consensus model to better visualize the agreement and constraints of each set of models. In summer, feral swine used lower slopes regardless of elevation, especially those closer to human-dominated spaces such as along paved and gravel roadways. In winter, feral swine maintained preference for lower slopes but preferred oak-dominated forest areas and selection for human development was less than in summer. Wildlife managers can use these models to better focus feral swine surveillance and management in GRSM. Managers can identify areas of high use by season and plan control activities that are both accessible and highly efficient. The combination and consensus framework presented here can be applied to other systems where species’ habitat selection may result in incongruous results across different levels of selection or seasons of interest.