bluuebunny/crossref_metadata_2025_split huggingface dataset:
Left-to-right ventricular volume ratio and outcome in heart failure with preserved ejection fraction
Authors: Aimo Alberto , Teis Albert , Kasa Gizem , Juncà Gladys , Lupón Josep , Domingo Mar , Ferrer Elena , Vallejo Nuria , Cediel Germán , Codina Pau , López-Ayerbe Jorge , Georgiopoulos Georgios , Martini Nicola , Emdin Michele , Bayes-Genís Antoni , Rapezzi Claudio , Delgado Victoria 
Published: July 2023

Background
Age-specific and gender-specific reference values for left ventricular (LV) and right ventricle volumes are available. The prognostic implications of the ratio between these volumes in heart failure and preserved ejection fraction (HFpEF) have never been evaluated.

Methods
We examined all HFpEF outpatients undergoing a cardiac magnetic resonance from 2011 to 2021. The left-to-right ventricular volume ratio (LRVR) was defined as the ratio between the LV and right ventricle end-diastolic volume indexes (LVEDVi/RVEDVi).

Results
Among 159 patients [median age 58 years (interquartile range 49–69), 64% men, LV ejection fraction 60% (54–70%)] the median LRVR was 1.21 (1.07–1.40). Over 3.5 years (1.5–5.0), 23 patients (15%) experienced all-cause death or heart failure hospitalization, and 22 (14%) cardiovascular death or heart failure hospitalization. The risk of all-cause death or heart failure hospitalization increased with an LRVR less than 1.0 or at least 1.4. An LRVR less than 1.0 was associated with a higher risk of all-cause death or heart failure hospitalization [hazard ratio 5.95, 95% confidence interval (CI) 1.67–21.28; P = 0.006] and cardiovascular death or heart failure hospitalization (hazard ratio 5.68, 95% CI 1.58–20.35; P = 0.008) as compared with LRVR 1.0–1.3. Furthermore, an LRVR at least 1.4 was associated with a higher risk of all-cause death or heart failure hospitalization (hazard ratio 4.10, 95% CI 1.58–10.61; P = 0.004) and cardiovascular death or heart failure hospitalization (hazard ratio 3.71, 95% CI 1.41–9.79; P = 0.008) as compared with LRVR 1.0–1.3. These results were confirmed in patients without dilation of either ventricle.

Conclusion
LRVR values less than 1.0 or at least 1.4 are associated with worse outcomes in HFpEF. LRVR may become a valuable tool for risk prediction in HFpEF.
del Nido versus blood cardioplegia in adult cardiac surgery: a meta-analysis
Authors: Malvindi Pietro Giorgio , Tian David H. , Bifulco Olimpia , Berretta Paolo , Alfonsi Jacopo , Cefarelli Mariano , Yan Tristan D. , Di Eusanio Marco 
Published: July 2023

Aims
Initially developed for myocardial protection in immature cardiomyocytes, del Nido cardioplegia has been increasingly used over the past decade in adult patients. Our aim is to analyse the results from randomized controlled trials and observational studies comparing early mortality and postoperative troponin release in patients who underwent cardiac surgery using del Nido solution and blood cardioplegia.

Methods
A literature search was performed through three online databases between January 2010 and August 2022. Clinical studies providing early mortality and/or postoperative troponin evaluation were included. A random-effects meta-analysis with a generalized linear mixed model, incorporating random study effects, was implemented to compare the two groups.

Results
Forty-two articles were included in the final analysis for a total of 11 832 patients, 5926 of whom received del Nido solution and 5906 received blood cardioplegia. del Nido and blood cardioplegia populations had comparable age, gender distribution, history of hypertension and diabetes mellitus. There was no difference in early mortality between the two groups. There was a trend towards lower 24 h [mean difference −0.20; 95% confidence interval (CI) −0.40 to 0.00; I
2 = 89%; P = 0.056] and lower peak postoperative troponin levels (mean difference −0.10; 95% CI −0.21 to 0.01; I
2 = 0.87; P = 0.087) in the del Nido group.

Conclusion
del Nido cardioplegia can be safely used in adult cardiac surgery. The use of del Nido solution was associated with similar results in terms of early mortality and postoperative troponin release when compared with blood cardioplegia myocardial protection.
Effect of acute CORticosteroids on conduction defects after Transcatheter Aortic Valve Implantation: the CORTAVI study
Authors: Barone Lucy , Muscoli Saverio , Belli Martina , Di Luozzo Marco , Sergi Domenico , Marchei Massimo , Prandi Francesca R. , Uccello Giuseppe , Romeo Francesco , Barillà Francesco 
Published: July 2023

Aims
Conduction abnormalities, requiring a permanent pacemaker (PPM), are the most common electrical complications after transcatheter aortic valve implantation (TAVI). The exact mechanism for conduction system defects is not yet clear. The local inflammatory process and edema are thought to play a role in the development of electrical disorders. Corticosteroids are effective anti-inflammatory and antiedematous agents. We aim to investigate the potential protective effect of corticosteroids on conduction defects after TAVI.

Methods
This is a retrospective study of a single center. We analyzed 96 patients treated with TAVI. Thirty-two patients received oral prednisone 50 mg for 5 days after the procedure. This population was compared with the control group. All patients were followed up after 2 years.

Results
Of the 96 patients included, 32 (34%) were exposed to glucocorticoids after TAVI. No differences in age, preexisting right bundle branch block or left bundle branch block, or valve type were seen among patients exposed to glucocorticoids versus those who were unexposed. We observed no significant differences between the two groups in the overall frequency of new PPM implantations during hospitalization (12% vs. 17%, P = 0.76). The incidence of atrioventricular block (AVB) (STx 9% vs. non-STx 9%, P = 0.89), right bundle branch block (STx 6% vs. non-STx 11%, P = 0.71), and left bundle branch block (STx 34% vs. non-STx 31%, P = 0.9) was not significantly different between the STx and non-STx groups. At 2 years after TAVI, none of the patients had implanted PPM or had severe arrhythmias documented by 24-h Holter ECG or cardiac examination.

Conclusion
Oral prednisone treatment does not appear to significantly reduce the incidence of AVB requiring acute PPM implantation after TAVI.
Desenvolvimento de tecnologias de uso dual pela base industrial de defesa como mecanismo de desenvolvimento econômico
Authors: Thaumaturgo Vergueiro Luiz Fabricio 
Published: July 2023

O desenvolvimento e uso de tecnologias passíveis de uso dual, entendidas como aquelas aptas ao emprego tanto em aplicações de uso civil, quanto em missões tipicamente militares (com ou sem pequenas adaptações), é um fenômeno histórico, principalmente nos países em desenvolvimento, onde uma crescente demanda de recursos para a saúde, educação, infraestrutura, etc., impõe a redução de gastos com os setores militares, praticamente obrigando que orçamentos de defesa passassem a ser conjugados com os recursos, também escassos, da iniciativa privada, em tecnologias adequadas simultaneamente para o meio civil (normalmente o seu maior consumidor), e para as Forças Armadas e de segurança pública. A maioria dos países desenvolvidos possui um sistema integrado de indústrias de defesa que se articula com a academia e o Poder Público para o desenvolvimento de tecnologias de alto valor agregado e que traz significativo progresso econômico e científico para a economia nacional. O Brasil possui uma Base Industrial de Defesa competente e relativamente desenvolvida, complementada por um ainda maior parque industrial e tecnológico, porém, flutuações econômicas colocam em risco a manutenção e avanço desse setor estratégico de qualquer economia nacional. Este artigo examina, em um nível preliminar, sob o enfoque da teoria dos sistemas complexos, as interações entre conhecimentos científicos e segmentos sociais muito diferenciados, as possibilidades de desenvolvimento de tecnologias de uso dual como ferramenta de fomento da Base Industrial de Defesa, e da economia científico-tecnológica como um todo.
Gestão e governança pública para o desenvolvimento - educação básica orientada por evidências
Authors: Araújo Messias Jorge Rodrigo , de Lima Lucio Magda 
Published: July 2023

A partir de dados do Pisa, da OCDE, do Censo do IBGE, da PNAD, do SAEB, e as metas de qualidade educacional do INEP, dentre outros, agregados às informações de financiamento da educação compreendemos como um ambiente de gestão e governança baseado em evidências empíricas pode contribuir para melhorar a tomada de decisão e, por conseguinte, as entregas públicas relacionadas à educação básica. Objetivamente, a partir da premissa de que a educação básica é motor propulsor para um projeto de desenvolvimento baseado em conhecimento e. por conseguinte, em tecnologia, pretende-se compreender e apresentar algumas análises promissoras e diretrizes que permitam a criação e implementação de ambientes de gestão e governança com capacidade de transcender aspectos de conformidade e controle e caminhar em direção a um ambiente em que informações possam se transformar em dados capazes de orientar a tomada de decisão de gestoras e gestores em todo o território nacional
TERRITORIAL DIFFERENTIATION OF RISK FACTORS FOR THE HEALTH OF THE POPULATION OF THE RUSSIAN FAR EAST
Authors: Изергина Е.В. 
Published: July 2023

Поведенческие и биологические факторы риска с повышенными уровнями показателей (курение, нездоровое питание, низкая физическая активность, избыточное потребление алкоголя, хроническое психоэмоциональное напряжение, высокие уровни гипертензии и глюкозы в крови) влияют на состояние здоровья населения (заболевания пищеварения; дыхательной, эндокринной и сердечно-сосудистой систем). Эти заболевания возникают при нездоровом образе жизни, снижая не только качество жизни, но и иммунитет населения. Это – управляемые внешние факторы, регулирование которых по-разному отражается на уровне здоровья населения различных территорий региона. Определение факторов риска, совместно с медицинской коррекцией нарушения обмена веществ входит в состав «первичной профилактики» заболеваний. В регионах Дальнего Востока России, где повышен уровень этих заболеваний (Арктические районы, Еврейская автономная область, Амурский край), также повышается заболеваемость инфекционными заболеваниями, в частности, Covid-19.
Behavioral and biological risk factors with elevated levels of indicators (smoking, unhealthy diet, low physical activity, excessive alcohol consumption, chronic psycho-emotional stress, high levels of hypertension and glucose in the blood) affect the health of the population (digestive diseases; respiratory, endocrine and cardiovascular systems). These diseases occur with an unhealthy lifestyle, reducing not only the quality of life, but also the immunity of the population. These are controlled external factors, the regulation of which affects the health level of the population of different territories of the region in different ways. The determination of risk factors, together with the medical correction of metabolic disorders, is part of the «primary prevention» of diseases. In the regions of the Russian Far East where the level of these diseases is increased (the Arctic regions, the Jewish Autonomous Region, the Amur Region), the incidence of infectious diseases, in particular Covid-19, is also increasing.
IDENTIFICATION OF CONTROL OBJECTS IN THE PRESENCE OF HIDDEN (LATENT) VARIABLES
Authors: Филаретов Г.Ф. , Репин А.Д. 
Published: July 2023

Рассматривается задача идентификации сложных технологических объектов, характеризующихся наличием различных неконтролируемых возмущений, высоким уровнем помех, неполнотой сведений о характере протекающих в них процессов. В такой ситуации, как правило, не удается построить адекватную работоспособную математическую модель объекта. Одной из возможных причин этого является наличие ранее неизученного влияния со стороны, так называемых, скрытых или латентных переменных. Предлагается для выявления их наличия и свойств использовать автоассоциативные искусственные нейронные сети (АИНС). С помощью имитационного эксперимента показана эффективность такого подхода, обеспечивающего в конечном итоге оптимизацию системы управления технологическим объектом.
The problem of identifying complex technological objects characterized by thepresence of various uncontrolled disturbances, a high level of interference, and incomplete information about the nature of the processes occurring in them is considered. In such a situation, as a rule, it is not possible to build an adequate workable mathematical model of the object. One of the possible reasons for this is the presence of a previously unexplored influence from the so-called hidden or latent variables. It is proposed to use auto-associative artificial neural networks (ANN) to identify their presence and properties. With the help of a simulation experiment, the effectiveness of this approach is shown, which ultimately ensures the optimization of the control system of a technological object.
METHOD FOR CREATING A PIEZOELECTRIC COATING WITH TARGETED PROPERTIES
Authors: Соколов Я.А. , Князева И.О. , Воронина С.Ю. , Руденко М.С. 
Published: July 2023

Данная статья описывает процесс получения пленок MXene методом вакуумной фильтрации. Исследователи использовали политетрафторэтилен в качестве фильтра и получили три образца пленок MXene разной концентрации. В дальнейших исследованиях авторы намерены проверить полученные образцы на их пригодность для мониторинга состояний конструкций из полимерных композиционных материалов.
This article describes the process of obtaining MXene films by vacuum filtration. The researchers used polytetrafluoroethylene as a filter and obtained three samples of MXene films of different concentrations. In further studies, the authors intend to test the obtained samples for their suitability for monitoring the state of structures made of polymer composite materials.
Desain Pembelajaran Kecerdasan Kinestetik Berbasis Pendekatan Reggio Emillia pada Anak Usia Dini
Authors: Sartika Indah Dwi , Wahyuni Desvi , Agustini Anisa 'A , Aryanti Aryanti , Sari Lia Dian , Larasati Woro Endah 
Published: July 2023

AbstractThis article aims to describe the use of the Reggio Emilia approach in learning based on kinesthetic intelligence. This research is based on the lack of a learning approach in schools so that kinesthetic intelligence stimulation is only done with simple activities such as gymnastics. The method used in this article uses the library research method or the library method with data collection techniques based on sources such as books, articles and others that are inseparable from the context of the core problem. In this study, the kinesthetic intelligence-based Reggio Emilia learning approach was designed using two class models, namely the ateliarista class and the clay class. The atelierista class is an art class to provide opportunities for children to carry out creative activities as freely as possible according to imagination or it can also be ordered by the educator. While the clay class is a clay class where children can form a work based on the learning theme that is being carried out. With the Reggio Emilia approach, this research might be used as a learning option in developing kinesthetic intelligence in early childhood. Keywords: Kinesthetic intelligence; reggio emillia approach.AbstrakArtikel ini bertujuan untuk mendeskripsikan penggunaan pendekatan Reggio Emilia dalam pembelajaran berbasis kecerdasan kinestetik. Penelitian ini didasarkan oleh kurangnya pendekatan pembelajaran di sekolah sehingga stimulasi kecerdasan kinestetik hanya dilakukan dengan kegiatan sederhana seperti senam. Metode yang digunakan dalam artikel ini menggunakan metode library research atau metode kepustakaan dengan teknik pengumpulan data berdasarkan sumber seperti buku, artikel dan lain-lain yang tidak terlepas dari konteks inti masalah. Pada penelitian ini pendekatan pembelajaran Reggio Emilia berbasis kecerdasan kinestetik dirancang dengan menggunakan dua model kelas yaitu kelas ateliarista dan kelas lempung. Kelas ateliarista merupakan kelas seni untuk memberikan kesempatan kepada anak untuk melakukan kegiatan kreatif sebebas mungkin sesuai imajinasi atau bisa juga atas perintah pendidik. Sedangkan kelas clay adalah kelas clay dimana anak dapat membentuk sebuah karya berdasarkan tema pembelajaran yang sedang dilaksanakan. Dengan pendekatan Reggio Emilia, penelitian ini mungkin dapat dijadikan salah satu pilihan pembelajaran dalam mengembangkan kecerdasan kinestetik pada anak usia dini.Kata kunci: Kecerdasan kinestetik; pendekatan reggio emillia.
Diseño de un protocolo con validez ecológica para la detección temprana de riesgo neurológico en población pediátrica de la primera infancia
Authors: Aldana Casas Angélica María , Pedraza Vargas Steve Fernando , López Hernández Karen Ginneth 
Published: July 2023

Introducción. El desarrollo del ser humano está determinado por factores biológicos, ambientales y contextuales que determinan la adquisición de habilidades neurológicas, y que bajo situaciones patológicas aumentan el riesgo de alteraciones en el neurodesarrollo desde etapas tempranas.
Objetivo. Diseñar un protocolo con validez ecológica para la detección temprana de riesgo neurológico en la primera infancia por parte de equipos interdisciplinarios de rehabilitación.
Métodos. Se realizó un estudio mixto, retrospectivo, transversal y descriptivo con un diseño exploratorio secuencial (DESPLOX). En la fase cualitativa se conformaron dos grupos focales: uno con padres (n=8) y otro con profesionales (n=6), de los cuales se obtuvieron las categorías del protocolo. En la fase cuantitativa se revisaron sistemáticamente artículos científicos (n=30) para la construcción de las orientaciones de acción. Finalmente, el protocolo se validó mediante un panel de expertos empleando el coeficiente de V de Aiken.
Resultados. En la fase cualitativa emergieron cuatro categorías: 1) detección temprana, 2) contextos del desarrollo, 3) plan de intervención y 4) calidad y humanización en la atención. En la fase cuantitativa se seleccionaron las orientaciones de acción ubicadas en los Q2 y Q3. Posteriormente se evidenció una validación del protocolo igual a X ̅ =0,98.
Conclusiones. Un protocolo de neurorrehabilitación válido ecológicamente se caracteriza por reconocer las percepciones, vivencias y experiencias de familiares y profesionales; recoger evidencia científica confiable; aportar orientaciones y recomendaciones sistémicas para la atención de niñas y niños, y contener criterios de validación de contenido.
Aplicación de la Clasificación Internacional del Funcionamiento, de la Discapacidad y de la Salud versión para la infancia y la adolescencia (CIF-IA) en fisioterapia con método específico en paciente con hipotonía y retraso en el desarrollo motor secundarios a síndrome de Bainbridge-Ropers
Authors: Castro Galeano Sandra Milena 
Published: July 2023

Introducción. El síndrome de Bainbridge-Ropers (BRS; MIM 615485) es un trastorno genético muy raro, identificado por primera vez en 2013, que ocasiona retraso en el desarrollo, hipotonía, discapacidad intelectual y problemas de crecimiento, en la alimentación y en la adquisición del lenguaje. En el manejo de este trastorno es importante tener en cuenta la Clasificación Internacional del Funcionamiento, de la Discapacidad y de la Salud versión para la infancia y adolescencia (CIF-IA) como herramienta para medir la evolución de la intervención fisioterapéutica en el tiempo.
Presentación del caso. Paciente femenina procedente de la ciudad de Medellín (Colombia), sin antecedente de parto de alto riesgo, quien presentaba hipotonía y retraso en el desarrollo motor secundarios a síndrome de Bainbridge-Ropers. A la menor se le aplicó la CIF-IA bajo 34 criterios seleccionados para la evaluación y seguimiento de la evolución y después de 11 meses de tratamiento con método Vojta y electroterapia se observó evolución favorable: logró marcha, adquisición del lenguaje, interacción con su familia, juego con su hermana, escolarización y control de esfínteres.
Conclusiones. El análisis longitudinal en función del tiempo de tratamiento de la paciente y a partir de la CIF-IA evidenció cambios de los 34 calificadores seleccionados en el transcurso de tiempo de intervención con la terapia Vojta en combinación con electroterapia. La intervención con el método Vojta no requirió un tratamiento prolongado (11 meses) ni una alta asistencia a consulta para alcanzar buenos resultados.
Efektifitas Metode Pembelajaran Timeline Terhadap Hasil Belajar Pendidikan Agama Islam
Authors: Suhirman Suhirman 
Published: July 2023

Abstract: The Effectiveness of the Timeline Learning Method on Learning Outcomes of Islamic Religious Education.The purpose of this study was to test the effectiveness of the Timeline Learning Method on the learning outcomes of Islamic Religious Education in 11th grade students at Madrasah Aliyah Negeri 2 Bengkulu City. This type of research is quantitative with a quasi-experimental approach. Data collection techniques using observation, tests, and documentation. The results of this study indicate: a). there is an increase in student learning outcomes after using the Timeline learning method in learning Islamic Religious Education 11th grade at MAN 2 Bengkulu City, b) a comparison of the Timeline and Concept Map learning methods: the Timeline learning method increases by 1%, the learning outcomes students will experience an increase of 0.580, and the Concept Map learning method increases 1%, so student learning outcomes increase by 0.336..Abstrak: Metode Pembelajaran Timeline, Concept Map, dan Hasil Belajar.Tujuan penelitian ini untuk menguji Efektifitas Metode Pembelajaran Timeline terhadap hasil belajar Pendidikan Agama Islam pada peserta didik kelas XI Madrasah Aliyah Negeri 2 Kota Bengkulu. Jenis penelitian ini merupakan kuantitatif dengan pendekatan kuasi eksperimen. Teknik Pengumpulan data menggunakan observasi, tes, dan dokumentasi. Hasil penelitian ini menunjukkan: a).terdapat peningkatan hasil belajar siswa setelah menggunakan metode pembelajaran Timeline dalam pembelajaran Pendidikan Agama Islam Kelas XI di MAN 2 Kota Bengkulu, b) perbandingan metode pembelajaran Timeline dan Concept Map: metode pembelajaran Timeline meningkat 1% maka hasil belajar siswa akan mengalami peningkatan 0,580, dan metode pembelajaran Concept Map meningkat 1% maka hasil belajar siswa meningkat sebesar 0,336.
PERBANDINGAN PENGGUNAAN METODE GROSS DAN METODE GROSS UP DALAM PERHITUNGAN PAJAK PENGHASILAN 21 DAMPAKNYA TERHADAP BEBAN DAN PAJAK PENGHASILAN BADAN PADA PT MUDA JAYA BERSAMA MELALUI IBS CONSULTING
Authors: Nyoman Dewi Sumahardanti NI , Fatimah Siti 
Published: July 2023

Laporan PKL dengan judul : “Perbandingan Penggunaan Metode Gross Dan Metode Gross Up Dalam Perhitungan Pajak Penghasilan 21 Dampaknya Terhadap Beban Dan Pajak Penghasilan Badan Pada PT Muda Jaya Bersama Melalui IBS Consulting”.Bertujuan untuk mengetahui tentang penggunaan metode gross dan metode gross up dalam menghitung pajak penghasilan 21. Untuk membandingkan teori yang sudah dipelajari selama bangku perkulihan dengan praktik lapangan selama menjalankan PKL.
Pelaksanaan Praktik Kerja Lapangan (PKL) dilaksanakan di PT.IBS Consulting yang beralamat di jalan Pangeran Diponegoro, Komplek Pertokoan Rangkang Jangkuk, Kelurahan Sayang-Sayang, Kecamatan Cakranegara, Kota Mataram. Penulis melaksanakan PKL kurang lebih selama 2 bulan yakni dari tanggal 13 Februari 2023 sampai dengan 13 April 2023. Kegiatan penulis selama PKL adalah ikut serta membantu memenuhi kewajiban perpajakan Wajib Pajak Orang Pribadi (OP) dan Badan melalui Kuasa Konsultan di PT. IBS Consulting terkhusus PT. Muda Jaya Bersama dalam menjalankan kewajiban perpajakannya.
Kata Kunci : Perbandingan, Gross, Gross Up