bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of agroforestry practices in Buno Bedele and Ilu Abba Bora zone of Oromia region, Ethiopia
Authors: Mezgebu Mosisa 
Published: May 2023

Abstract
Agroforestry practices are considered as one of the major source of food and income to meet the needs and the wellbeing of the rural community. This study was conducted in Buno Bedele and Ilu Abba Bora zone, with the aim to identify and assess agroforestry practice, constraints and Importance and farmers’ perception on the existing agroforestry practice in study area. Accordingly 3 districts from each zone and 12 Kebele in 6 districts were selected by purposely sampling methods and similarly 299 household were selected. Semi-structured questionnaire data was generated by conducting household survey interview, key informant, and direct field observation were applied. Based on the respondent’s idea across the both zones, the results of this study have shown that ,Homegardens (96%), Coffee based agroforestry practice (91.3) ,Fruit trees based agroforestry practice (86.6%), woodlot (65.6%), windbreak/shelterbelts (62.5%), Trees on rangeland (57.2%), Life fencing (53.8%), Parkland agroforestry (43.1%), Taungya (26.4%) and Alley cropping (16.7%) are the exist agroforestry practices in the study area. The major Importance of agroforestry practices were for income, regulated climates, soil improvement, used for shade, food and livestock feed, properly using the land, construction, fuel wood and timber. On the other hand, impacts of wild animals, Insect pest and disease, Competition trees with crop (i.e. shading effect), shortage of land for tree planting, lack of capital, lack of knowledge, taking long time for profit, lack of seed accessibility and Shortage of labor the major constraints recorded in the study areas. Majority of respondents were strongly agreed with the agroforestry practices; increase farm income, improve soil fertility and conserved soil and water, saved time on collecting fodder and fuel wood from the forest and improve the natural condition. Those show that the respondents in study area have positive attitude with existing agroforestry practices. Albizia gummifera (78.2%), Cordia africana (67.9%) and Croton macrostachyus (63.2%) were the most common trees that dominated in the study area. Albizia gummifera (67.2%) and Cordia africana (61.9%) also were most preferred trees by farmers in field. Avocado (91.3%), Banana (79.6%) and Mango (61.9%) were the most dominant fruit trees/shrubs, while Maize (95%), Coffee (91.3%), Teff (76.6%), Chat (65.9%) and Sorghum (52.8%) were the most dominant crops and Cow, Oxen, Calve, Chicken were the most dominant livestock. The study recommends further studies have to be done on positive interaction trees/shrubs selection in component, management and introducing new agroforestry practices and manage the exist agroforestry practice at study are.
In vivo deuterium magnetic resonance imaging of xenografted tumors following systemic administration of deuterated water
Authors: Brender Jeffrey R. , Assmann Julian C. , Farthing Don E. , Saito Keita , Kishimoto Shun , Warrick Kathrynne A. , Maglakelidze Natella , Larus Terri L. , Merkle Hellmut , Gress Ronald E. , Krishna Murali C. , Buxbaum Nataliya P. 
Published: May 2023

Abstract
In vivo deuterated water (2H2O) labeling leads to deuterium (2H) incorporation into biomolecules of proliferating cells and provides the basis for its use in cell kinetics research. We hypothesized that rapidly proliferating cancer cells would become preferentially labeled with 2H and, therefore, could be visualized by deuterium magnetic resonance imaging (dMRI) following a brief period of in vivo systemic 2H2O administration. We initiated systemic 2H2O administration in two xenograft mouse models harboring either human colorectal, HT-29, or pancreatic, MiaPaCa-2, tumors and 2H2O level of ~ 8% in total body water (TBW). Three schemas of 2H2O administration were tested: 1) starting at tumor seeding and continuing for 7 days of in vivo growth with imaging on day 7, 2) starting at tumor seeding and continuing for 14 days of in vivo growth with imaging on day 14, and 3) initiation of labeling following a week of in vivo tumor growth and continuing until imaging was performed on day 14. Deuterium chemical shift imaging of the tumor bearing limb and contralateral control was performed on either day 7 of 14 after tumor seeding, as described. After 14 days of in vivo tumor growth and 7 days of systemic labeling with 2H2O, a clear deuterium contrast was demonstrated between the xenografts and normal tissue. Labeling in the second week after tumor implantation afforded the highest contrast between neoplastic and healthy tissue in both models. Systemic labeling with 2H2O can be used to create imaging contrast between tumor and healthy issue, providing a non-radioactive method for in vivo cancer imaging.
Evidence for the Augmented Cd(II) Biosorption by Cd(II) resistant strain Candida tropicalis XTA1874 From Contaminated Aqueous Medium
Authors: Bhattacharyya Kaustav , Bhattacharjee Neelanjan , Ganguly Subhadeep 
Published: May 2023

Abstract
Cadmium is one of the most dreadful heavy metals and is becoming a major toxicant in ground water with increasing concentration above the WHO Guidelines in drinking water (0.003ppm). The conventional physico-chemical remediation techniques are not favorable in removing the contaminants such as Cd(II) fruitfully. Bio-based techniques used in Cd(II) removal from contaminated water provide cheap, eco-friendly and efficient means of environmental remediation. The present study is aimed at determining the optimized nutritional conditions for the optimal growth and Cd(II) remediation capacity for a developed Cd(II) resistant yeast strain named Candida tropicalis XTA 1874 isolated from contaminated water-body in West Bengal. By analyzing the optimization conditions, a synthetic medium was developed and the composition has been given in the main text. The biosorption process followed pseudo second order kinetics proving chemisorption as the rate limiting step in the adsorption process. The equilibrium biosorption of Cd(II) by the strain was fitted to the Langmuir model and hence the biosorption was a monolayer process both before and after optimization. The strain showed much better Cd(II) adsorption capacity under the optimized nutritional conditions (qmax=847.476±0.008 mg/g). The above findings amply demonstrated the strain to be an effective biosorbent in removing Cd(II) from contaminated water.
Experiments investigating the thermal runaway behavior of cyclically aged lithium batteries at various SOCs
Authors: Wei Ningning , Li Minghai , Qi Changbao 
Published: May 2023

Abstract

Thermal runaway (TR) is a critical safety concern in energy storage batteries, and the effects of aging on battery TR characteristics are of utmost importance. In this study, prismatic lithium-ion batteries with a nominal capacity of 40 Ah and Li(Ni0.6Co0.2Mn0.2)O2 cathode material were subjected to cycling aging up to 80% of their rated capacity. The TR characteristics of the aged batteries were investigated at different state of charge (SOC) levels, including 25%, 50%, 75%, and 100%, in an inert environment. The findings revealed that as SOC increased, various parameters, such as the maximum temperature of the safety valve outlet (TE,max), the highest temperature on the battery surface (TS,max), the highest temperature in the experimental chamber (TC,max), the mass loss rate, the highest temperature at the positive electrode tab (TP,max), and the highest temperature at the negative electrode tab (TN,max), all exhibited an upward trend. Additionally, higher SOC levels resulted in higher total gas production, while normalized gas production showed a decreasing trend. These results provide valuable insights for early warning of thermal hazards and internal thermal state analysis of batteries, which can inform the design of energy storage batteries with improved thermal safety measures.
On the Determination of the Friction-Caused Energy Losses and its Potential for Monitoring Industrial Tribomechanical Systems
Authors: Miljanić Dragomir , Milovanovic Vladimir , Vukelić Djordje , Rakić Dragan , Tadić Branko 
Published: May 2023

Abstract
The paper refers to a new method to quantify the energy losses due to frictional effects and imperfections in contacts in the case of real industrial tribomechanical systems. Whereby energy losses represent an integral indicator of quality of the real industrial tribomechanical system, in terms of the characteristics of the contact element materials, geometric accuracy, and manufacturing and assembly errors. This paper presents a very complex theoretical model based on the differential equation of motion of a real tribomechanical system down a steep plane. The outputs of the theoretical model are exact mathematical expressions that define the current values of the coefficient of friction and the friction-caused energy losses. The measuring system enables the quantification of current values of the distance traveled per unit of time. Based on a series of experimentally determined values of distance traveled per unit of time, the values of energy losses of the real industrial tribomechanical system are determined using the developed theoretical model and the appropriate software support. The obtained results indicate a high reliability, a large potential and a wide range of possible applications of the proposed method.
A new nematode (Mermithidae) and spider (Araneae) associations, along with a molecular analysis of mermithids hosted in the spider
Authors: Kostro-Ambroziak Agata , Jabłońska Urszula , Świsłocka Magdalena , Wiśniewski Konrad , Kupryjanowicz Janusz 
Published: May 2023

Abstract
Mermithid parasitoids are well known to infect spiders, however, their impact on the hosts and their taxonomic identity are still poorly analyzed. We present the first record of a mermithid nematode infection in the spider genera Piratula (Lycosidae) and Coelotes (Agelenidae), and in the species Alopecosa pulverulenta and Pardosa paludicola (Lycosidae). We describe the interesting maldevelopment of the spiders’ female genitalia induced by the parasitoid and summarize the data on the impact of nematode parasitoids on spider development and behaviour. Phylogenetic analysis, based on the 18S rRNA, showed that spider’ parasitoids arose independently in different phylogenetic branches of the family Mermithidae.
The effect of growth hormone on low-prognosis patients: a retrospective study based on POSEIDON criteria
Authors: Li Qiu-ping , Zhang Yun , Xiong Fang , Zheng Han , Gu Yan-fang , Zhu Yun 
Published: May 2023

Abstract
Objective: To investigate the effect of growth hormone on low-prognosis patients who were diagnosed by POSEIDON criteria.
Methods: Poor ovarian reserve patients were included if their AMH <1.2ng/ml, and according to POSEIDON criteria they were further divided into Group 3 and Group 4. Mild stimulation protocol was adopted in all groups. Growth hormone was administered in GH group. Further study on non-first cycles was conducted. Linear regression and logistic regression analysis were carried out to control the confounding factors.
Results: A total of 574 cycles (155 in GH group, 419 in Control group) were analyzed. For all the poor ovarian reserve patients, there were no significant differences between GH and control group, in aspects of HMG dosage, duration of HMG, the number of oocytes retrieved, the number of 2PN, the number of embryos, transferrable embryos ,good-quality embryos, clinical pregnancy rate, miscarriage rate and clinical live birth rate. In stratified analysis, the variables of G4 were not significantly different, and in G3, duration of HMG (8.11±1.86vs. 8.80±1.98, P﹤0.05) was significantly different. Further study on non-first cycle patients, a total of 274 cycles (122 in GH group, 152 in Control group) were analyzed, there were no differences between GH group and control group, in aspects of HMG dosage, duration of HMG, the number of oocytes retrieved, the number of 2PN, the number of embryos, transferrable embryos ,good-quality embryos, clinical pregnancy rate, miscarriage rate and clinical live birth rate. In stratified analysis, the variables of G3’ were not significantly different. In G4’, duration of HMG (8.74±2.31 vs. 7.90±2.56, P﹤0.05) was significantly different, the number of oocytes retrieved(8.74±2.31 vs. 7.90±2.56, P﹤0.05), clinical pregnancy rate(22.97% vs. 8.45%, P﹤0.05), and clinical live birth rate(14.86% vs. 4.23%, P﹤0.05) were significantly different between GH and control groups. The outcomes of linear regression and logistic regression analysis were approximately consistent with that of Chi square test.
Conclusions: GH co-treatment with the mild stimulation protocol in poor ovarian reserve patients who reached or were older than 35 years old, and failed in at least one previous cycle, could significantly increase the number of oocytes retrieved, clinical pregnancy rate and live birth rate.
Clinical availability and characteristics of multigene panel testing for recurrent/advanced gynecologic cancer
Authors: Kitazawa Shoko , Chiyoda Tatsuyuki , Nakamura Kohei , Sakai Kensuke , Yoshihama Tomoko , Nishio Hiroshi , Kobayashi Yusuke , Iwata Takashi , Banno Kouji , Yamagami Wataru , Nishihara Hiroshi , Aoki Daisuke 
Published: May 2023

Abstract
Background Japan’s health insurance covers multigene panel testing. This study aimed to determine the potential availability and utility of gene panel testing clinically in gynecologic oncology.Methods We analyzed the characteristics of patients with gynecologic cancer who underwent gene panel testing using FoundationOne® CDx or OncoGuide™ NCC Oncopanel between November 2019 and October 2022.Results Out of 102 patients analyzed, 32, 18, 43, 8, and 1 had cervical, endometrial, ovarian cancers, sarcoma, and vaginal cancer, respectively. Druggable gene alteration was found in 70 patients (68.6%; 21 with cervical cancer, 15 with endometrial cancer, 28 with ovarian cancer, 5 with sarcoma, and 1 with others). The most common druggable gene alteration was PIK3CA mutation (n = 21), followed by PTEN mutation (n = 12) and high tumor mutation burden (TMB-H) (n = 11). TMB-H was detected in 5 patients with cervical cancer, 5 with endometrial cancer, and 1 with endometrial stromal sarcoma. Eleven patients (10.8%) received molecularly targeted therapy according to their gene aberrations. Gene panel testing was mostly performed when the second-line treatment was ineffective. Of all 102 patients, 60 did not have recommended treatment, and 15 died or had worsened conditions before obtaining the test results.Conclusion Through multigene panel testing, although many patients had druggable gene alterations, 10.8% of them received the recommended treatment. TMB-H was mainly observed in cervical/endometrial cancer, suggesting its potential as a therapeutic biomarker of immune checkpoint inhibitors. Furthermore, patients’ prognosis and performance status should be considered before performing the test.
Grindability of γ-TiAl intermetallic compounds during ultrasonic vibration-assisted high efficiency deep grinding process
Authors: Wang Xiaowei , Tang Yi , Zhao Biao , Chen Tao , Ding Wenfeng , Xu Jiuhua 
Published: May 2023

Abstract
Gamma titanium-aluminum intermetallic compounds (γ-TiAl) have an important application significance in the field of aero-engines owing to their excellent mechanical properties (e.g., high-temperature resistance, high toughness, etc). Grinding as an important method was used to realize the high efficiency and precise machining for difficult-to-cut materials. However, the machining defects (e.g., adhesion, cracks, and even burns, etc) were confronted on machined surface of γ-TiAl materials under high grinding force and temperature loads. In this case, the new machining methods combined with the ultrasonic vibration and high-efficiency deep grinding technology was proposed to improve the machining quality and efficiency. Comparative trials of ultrasonic vibration-assisted high efficiency deep grinding (UVHEDG) and high efficiency deep grinding (HEDG) were carried out to study the grinding performance, in terms of the grinding force, grinding temperature, specific grinding energy, and machining surface quality. Results show that UVHEDG possess the lower grinding force and temperature by 38.69% and 39.05% compared with HEDG, respectively. In addition, the employment of ultrasonic vibrations contributes to maintain the abrasive sharpness, and thus the specific grinding energy is reduced by 23.95%. Ground surface roughness can be reduced by 19.53%, and the grinding surface quality is effectively improved due to the lubrication effect and track overlap effect under ultrasonic vibration.
Higher Quantiles of Sea Levels Rise Faster in Baltic Sea Climate Projections
Authors: Dieterich Christian , Radtke Hagen 
Published: May 2023

Abstract
Absolute sea levels in the Baltic Sea will rise under the influence of climate warming, similar to those in the world ocean. For extreme sea levels, there are indications that they will rise even faster than mean sea levels, but that topic is still controversially discussed and existing studies point into different directions. We analyzed a regional climate model ensemble for the Baltic Sea for future sea level changes. We find that the rate of change differs between high sea levels and the average: In the eastern part of the Baltic Sea, the 99th percentile of sea level was predicted to rise faster than the median. In the south-western part, the relation was opposite. Thus, our simulations predict a change not only in the sea level mean, but also in its distribution. This pattern was almost consistent between the individual ensemble members. We investigated the 99th percentile as a proxy for extreme sea levels, since their partially stochastic nature limits the predictive skill of our 20-member ensemble. Our findings imply that adapting coastal protection to mean sea level change only may be regionally insufficient.
Transcriptomic signatures of feline chronic gingivostomatitis are influenced by upregulated IL6
Authors: Peralta Santiago , Grenier Jennifer K. , Webb Suzin M. , Miller Andrew D. , Miranda Ileana C. , Parker John S.L. 
Published: May 2023

Abstract
Feline chronic gingivostomatitis (FCGS) is a relatively common and debilitating disease characterized by bilateral inflammation and ulceration of the caudal oral mucosa, alveolar and buccal mucosa, and varying degrees of periodontal disease. The etiopathogenesis of FCGS remains unresolved. In this study, we performed bulk RNA-seq molecular profiling of affected tissues derived from a cohort of client-owned cats with FCGS compared to tissues from unaffected animals, to identify candidate genes and pathways that can help guide future exploration of novel clinical solutions. We complemented transcriptomic findings with immunohistochemistry and in situ hybridization assays to better understand the biological significance of the results and performed RNA-seq validation of selected differentially expressed genes using qPCR assays to demonstrate technical reproducibility. Transcriptomic profiles of oral mucosal tissues in cats with FCGS are enriched with immune- and inflammation-related genes and pathways that appear to be largely influenced by IL6, and include NFKB, JAK/STAT, IL-17 and IFN type I and II signaling, offering new opportunities to develop novel clinical applications based on a more rational understanding of the disease.
Modeling and Managing Household Travels Taking Into Considering of School Bus
Authors: DAI Qing , ZHANG Jiajia , LIN Zhengkui , LIANG Zonglin 
Published: May 2023

Abstract
This paper examines the household commuting problem in a bi-modal transportation that includes both autos and school buses. Traditional studies of household commuting have assumed that adults first drop off their children at school before driving to work. However, with the increasing use of school buses in metropolitan areas, household commuting patterns have changed. This paper investigates the impact of school buses on household travel behavior during morning peak hours. Simultaneously, this paper also takes into account the positive utilities of household commuters’ activities at home, school and workplace, as well as the negative utilities of travel time and schedule delay. In this paper, based on activity approach, first, a net utility function is developed using these factors. Then, based on the net utility function, the occurrence conditions of all the possible equilibrium travel patterns are analytically solved and the properties of the user equilibrium are researched. Specifically, this paper examines how equilibrium travel patterns are affected by school bus fares and school-work start time difference, and at equilibrium travel patterns, the net utilities of household commuters are also analyzed. Finally, a first-best time-varying toll model is suggested to alleviate traffic congestion caused by household commuting.
Integrated Supercritical CO2 and subcritical water extraction of high-value compounds to valorize brown macroalgae (Padina tetrastromatica and Turbinaria conoides) harvested from Indian coastline
Authors: Hans Nidhi , Malik Anushree , Naik Satyanarayan 
Published: May 2023

Abstract
This work centred on the valorisation of brown macroalgae by sequentially extracting multiple value-added compounds using developing green extraction techniques. Supercritical fluid extraction (SFE) was used to extract lipids from biomass, which were found to be rich in polyunsaturated fatty acids with multiple nutraceutical applications. Using the subcritical water (ScW) technique, 48% sodium alginate and 11% protein were recovered from the SFE residual biomass. The alginate derived from ScW revealed the presence of mannuronic (M) and guluronic acids (G) with M/G ratio greater than 1, fulfilling WHO and FAO guidelines for the nutraceutical and pharmaceutical industries. Due to high concentration of polyphenolic compounds, alginate exhibited up to 80% invitro 2,2-diphenyl-1-picrylhydrazyl scavenging activity and 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) radical scavenging activity. Thus, an integrated method has been designed to valorize biomass by extracting commercially relevant valuable compounds from macroalgae utilising green and sustainable technologies, which could be used for the scale-up extraction of these compounds by a variety of industrial sectors.
Novel multiple localized wave solutions and soliton molecules for the (2+1)-dimensional Korteweg-de Vries equation
Authors: Zhuang Jian-Hong , Chen Xin , Chu Jingyi , Liu Yaqing 
Published: May 2023

Abstract
This article focuses on the exploration of novel soliton molecules for the (2+1)-dimensional Korteweg-de Vries equation. Specifically, Hirota bilinear form is derived through Bell polynomial method, and a soliton molecule comprising one lump soliton and an arbitrary number of line solitons or/and breather solitons is derived through the introduction of a longwave limit and new constraint conditions between the parameters of the N-soliton solutions and velocity resonance. The paper presents both analytical and graphical demonstrations of a range of interactions, showcasing the propagation of nonlinear localized waves. The findings of this study could contribute to a better understanding of physical phenomena associated with the propagation of nonlinear localized waves.