bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Role of Personal Commitment in Association Between Aerospace Education and Service Experience Through Quality Design: A Moderated Mediation Model
Authors: Uyoga Diane , Bonuke Ronald 
Published: July 2023

Abstract
This study investigates whether personal commitment moderates the effect of aerospace education on service experience through quality design. A cross-sectional study using a close-ended questionnaire was administered to a sample of 174 aviation students of Moi University, Kenya. Moderated mediation analyses were conducted using the PROCESS macro in order to investigate the relationship among variables. The results showed that the association between aerospace education and service experience was significant, and this association was mediated by quality design. The mediated effect of quality design was moderated by personal commitment. Based on the findings, companies involved in aviation should focus on improving the good environment of the service encounter (i.e., education, quality design and commitment) to enhance service experience. The findings made a contribution in terms of allowing us to understand the factors that can enhance service experience in the aviation industry.
Solid Rocket Boosters Separation System Development for the ILR-33 Amber 2K Rocket
Authors: Kierski Jan , Pazik Arthur , Cieśliński Dawid 
Published: July 2023

Abstract
The paper presents the development process of the solid rocket boosters (SRBs) separation system of the ILR-33 AMBER 2K rocket. A redesign of the system was required due to the development of new, larger SRBs. The main system requirements were transmission of forces and moments between the SRBs and the main stage, execution of the separation process at a given moment in flight and mechanical integration simplification. A set of aerodynamics calculations were performed. With the use of computational fluid dynamics software, forces acting on the booster during separation for several angles of attack, as well as the critical booster deflection angle, have been determined. Next, a mathematical model was created to define the load spectrum acting on the system during the flight and separation phases, covering both static and dynamic loads. All the internal and external force sources were considered. A series of motion dynamics simulations were conducted for representative flight cases. Then, the system operational parameters were verified with the use of dedicated ground test facilities. Necessary calibrations of the mathematical model were then implemented, leading to a high level of confidence with the empirical data obtained, thereby leading to a successful system qualification for the flight campaign.
Design Method for Pressurised and Non-Pressurised Tail Cargo Door’s Fairings Compartment in Transport Category Aircraft
Authors: Grebenikov Oleksandr , Humennyi Andrii , Loginov Vasyl , Dveirin Olexandr , Konyshev Dmytro 
Published: July 2023

Abstract
The method for determining the main parameters of the tail cargo doors of transport category aircrafts is developed. A methodology for the ascertainment of these parameters has been described. An example based on an existing transport aircraft is considered. Gathered were information pertaining to the necessary design, operational and regulatory parameters and requirements of the international regulatory organisations Federal Aviation Regulations (FAR), Certification Specification (CS) and Aviation Regulations (AR). The principle of determining the dimensions of the cargo compartment, cargo floor and the hitting platforms, in the form of a ramp with a pressure door and ladders, is presented based on the initial data. Considering the described loading and unloading, as well as landing, operations, the dependence of the ramp length on the length of the cargo floor is ascertained. A method for designing a cargo door fairings in the transport category aircraft fuselage tail part is presented. The main features of the fairings compartment have been determined, together with those of its main components and their varieties, depending on the scheme of the cargo door. Information is provided on the fairings compartment structural elements parameters selection.
Experimental Investigation of the Active Flow Control over a Cranked-Delta Wing
Authors: Mahdavi Zafarghandi Fatemeh , Reza Soltani Mohammad 
Published: July 2023

A series of experiments was carried out to investigate the effects of active flow control on the aerodynamic characteristics of a cranked-delta-wing model at a subsonic speed. A dielectric barrier discharge (DBD) plasma actuator was used to improve the aerodynamic performance of the half-span cranked-delta-wing model at various angles of attack. The model had inboard and outboard sweepback angles of 57 and 38 deg, respectively. The surface pressure distribution was obtained at five streamwise stations and at two ray stations. All data were obtained at a constant Reynolds number of [Formula: see text] and at various angles of attack: [Formula: see text]. The results showed that the pulsed DBD plasma actuator improved the aerodynamic performance of the cranked-delta-wing model by preventing flow separation at high angles of attack. The deep stall angle of attack was delayed up to 6 deg, and the poststall suction coefficient was increased approximately 30% at an angle of attack of about [Formula: see text] when the pulsed DBD plasma was applied at its optimum condition ([Formula: see text] and duty [Formula: see text]). It was found that the pulsed plasma actuator suppressed the wake flow in the forward portion of the wing at poststall angles of attack, thus delaying the flow separation. However, the effects of the DBD actuator at very high angles of attack on the flow reattachment process at the rear portion of the wing for the present DBD setting were seen to be minimal. The induced flow by the pulsed DBD plasma actuator influenced the vortex merging phenomena and delayed the onset of the outer vortex burst at prestall angles of attack.
Caracterización proximal, microbiológica y sensorial de diversos tipos de quesos tipo Chihuahua, elaborados en la Zona Norte de Zacatecas
Authors: Morales-Cruz J. , Cruz-Guillen F.J. , González-Arellano M.A. , Cruz-Guillen F.J. , Esparza-García V.M. 
Published: July 2023

Se realizó la caracterización proximal, microbiológica y sensorial de diversos quesos tipo Chihuahua elaborados en la zona norte del estado de Zacatecas a los cuales se les efectuaron las determinaciones proximales, nutricionales, sensoriales y microbiológicas, se compararon el San Lorenzo y el queso Ramírez. Los resultados fueron: Queso San Lorenzo: proteína cruda 15.6 %, grasa 31.5 %, humedad 42.4 %, cenizas 3.3 % y carbohidratos 7.2 %. Queso Ramírez: proteína cruda 16.8 %, grasa 33.0 %, humedad 39.4 %, cenizas 3.1 % y carbohidratos 7.7 %. Los dos presentan resultados similares y se consideran como productos nutricionalmente aceptables. Los resultados sensoriales fueron muy buenos ya que los atributos con mayor aceptabilidad son: el sabor (QS 4.5 Y QR 3.8), olor (QS 4 Y QR 3.7), color (QS 4.6 y QR 3.5) y en textura (QS 4.2 y QR 4.2). Sensorialmente el queso San Lorenzo presenta una buena calidad organoléptica, según los resultados de los evaluadores. Los resultados microbiológicos de los dos quesos, están dentro de lo que nos exige la NOM-213-SSA1-2017. De manera general se concluye que el queso San Lorenzo posee mejor calidad que el Queso Ramírez.
Evaluación de la estabilidad lipídica en hamburguesas de pollo adicionadas con extractos de guayaba (Psidium guajava L.) como antioxidantes
Authors: Herrera Méndez C.H. , Miranda Roque A. , Trujillo Santoyo A.D. , Arroyo Figueroa G. , Dzul Cauich J.G. , Medina Saavedra T. 
Published: July 2023

Se analizó si extractos de guayaba retrasan la oxidación lipídica de la carne en hamburguesas. Se caracterizó la guayaba: pH 4.02 ± 0.11; acidez 0.14 ± 0.010; % humedad 83.80 ± 0.392; % cenizas 0.34 ± 0.065; °Bx 12.98 ± 0.399 y % proteína 12.54 ± 1.135. Estudios a extractos: cáscara: 1544.4 ± 0.013 mg ácido gálico/100 g (fenoles totales), 43.79 ± 0.014 % de taninos, 261.334 ± 2.665 mg ácido ascórbico/100 g y 91.65 ± 0.003% inhibición (DPPH); pulpa: 563.1 ± 0.035 mg ácido gálico/100 g, 38.18 ± 0.009 % de taninos, 237.622 ± 2.059 mg ácido ascórbico/100 g y 88.67 ± 0.004 % inhibición; extracto combinado: 1237.3 ± 0.221 mg ácido gálico/100 g, 42.44 ± 0.007 % de taninos, 142.655 ±1.026 mg ácido ascórbico/100 g y 87.67 ± 0.004 % inhibición. Se determinaron el pH, color y oxidación de lípidos (TBARS). La oxidación del control fue 12.711 a 18.727 mg malondialdehído/kg de carne, mientras que en la carne tratada fue menor, siendo P80 el mejor tratamiento con un valor de 14.918 ± 0.019 mg malondialdehído/kg de carne, con lo que se concluye que al adicionar extractos de guayaba se puede disminuir la oxidación lipídica de la carne.
Analisis Kemampuan Komunikasi Statistis di Tinjau dari Gender Pada Siswa Kelas VIII SMP Negeri 22 Mataram Tahun Ajaran 2022/2023
Authors: Ekawati Baiq Noviana , Sarjana Ketut , Hayati Laila , Soeprianto Harry 
Published: July 2023

Seiring dengan perkembangan ilmu pengetahuan dan teknologi, peran matematika sebagai salah satu ilmu dasar yang memiliki nilai esensial yang dapat diterapkan di berbagai bidang kehidupan menjadi sangat penting. Penelitian ini bertujuan untuk menganalisis kemampuan komunikasi statistis siswa ditinjau dari gender pada siswa kelas VIII SMP Negeri 22 Mataram tahun ajaran 2022/2023. Jenis penelitian ini adalah penelitian Deskriptif kualitatif penelitian ini mencakup masalah deskripsi murni tentang program dan atau pengalaman orang di lingkungan penelitian. Hasil penelitian ini menunjukan bahwa ada perbedaan antara kemampuan komunikasi statistis siswa laki-laki dan siswa perempuan hal ini dapat dilihat pada hasil tTabel dengan menggunakan asumsi varian tak sama.Kemampuan komunikasi statistis siswa dikelompokan menjadi 4 kategori, dari 26 siswa perempuan diperoleh bahwa 11 siswa berkemampuan komunikasi statistis dalam kategori sangat baik dengan presentase 48%, 7 siswa berkemampuan komunikasi statistis dalam kategori baik dengan presentase 30%, 5 siswa berkemampuan komunikasi statistis dalam kategori cukup baik dengan presentase 22 %, dan tidak terdapat siswa perempuan yang berkemampuan komunikasi statistis dalam kategori kurang baik. Sedangkan dari 17 siswa laki-laki diperoleh 4 siswa yang berkemampuan komunikasi statistis dalam kategori sangat baik dengan presentase 24%, 3 siswa berkemampuan komunikasi statistis dalam kategori baik dengan presentase 18%, 8 siswa berkemampuan komunikasi statistis dalam kategori cukup baik dengan presentase 47%, 2 siswa berkemampuan komunikasi statistis dalam kategori kurang baik dengan presentase 12%.
Tricuspid regurgitation: a hidden risk factor for atrial fibrillation related stroke?
Authors: Kim Yong Soo , Jeong Han-Gil , Hwang In-Chang , Kim Beom Joon , Kwon Joon-Myung , Bae Hee-Joon , Han Moon-Ku 
Published: July 2023

Background and purposeTricuspid regurgitation (TR) is a common but overlooked valvular disease, and its association with the etiologic subtypes of ischemic stroke is unclear. We explored the relationship between TR and atrial fibrillation (AF) in patients with acute ischemic stroke.MethodsThis retrospective analysis of ongoing stroke registry assessed 6,886 consecutive acute ischemic stroke patients who underwent transthoracic echocardiography during their in-hospital care. Multivariable logistic regression models adjusted for age, sex, stroke characteristics, and echocardiographic indices were used to investigate the association between TR and total AF, and newly diagnosed AF during hospitalization and a 1-year follow-up period, respectively.ResultsTR was present in 877 (12.7%) patients (mild, 9.9%; moderate, 2.4%; severe, 0.5%). AF was identified in 24.1% (medical history, 11.1%; first detected in the emergency room, 6.6%; newly diagnosed after admission, 6.4%). TR was associated with AF [adjusted odds ratio (aOR) 4.87 (95% confidence interval (CI), 2.63–9.03)], compared with no/trivial TR. The association between TR and AF was consistent regardless of severity (aOR [95% CI], 4.57 [2.63–7.94] for mild and 7.05 [2.57–19.31] for moderate-to-severe TR) or subtype of TR (5.44 [2.91–10.14] for isolated and 3.81 [2.00–7.28] for non-isolated TR). Among the AF-naïve patients at admission, TR was associated with newly diagnosed AF during hospitalization and a 1-year follow-up period (aOR [95% CI], 2.68 [1.81–3.97]).ConclusionsTR is associated with AF in acute ischemic stroke patients regardless of severity and subtypes of TR. TR is also associated with newly diagnosed AF after stroke.
Dietary intervention reprograms bone marrow cellular signaling in obese mice
Authors: Zheng Yuxuan , Yan Jiren , Zhang Xiaofu , Cui Hailong , Wei Zhenyuan , Li Xiaoying , Wang Qiuyu , Zhong Biao 
Published: July 2023

ObjectivesThe current study aimed to investigate the pathogenesis of obesity-induced impaired bone mass accrual and the impact of dietary intervention on bone density in the mouse model of obesity.MethodsMice were fed with chow diet (CD) for 10 months, high-fat-diet (HFD) for 10 months, or HFD for 6 months then transferred to chow diet for 4 months (HFDt).ResultsWeight loss and decreased intrahepatic lipid accumulation were observed in mice following dietary intervention. Additionally, HFD feeding induced bone mass accrual, while diet intervention restrained trabecular bone density. These changes were further reflected by increased osteogenesis and decreased adipogenesis in HFDt mice compared to HFD mice. Furthermore, HFD feeding decreased the activity of the Wingless-related integration site (Wnt)-β-Catenin signaling pathway, while the Wnt signaling was augmented by diet intervention in the HFDt group.ConclusionsOur findings suggest that a HFD inhibits bone formation and that dietary intervention reverses this inhibition. Furthermore, the dietary intervention was able to compensate for the suppressed increase in bone mass to a level comparable to that in the CD group. Our study suggests that targeting the Wnt signaling pathway may be a potential approach to treat obesity-induced impaired bone mass accrual.
Exercise for prevention of falls and fall-related injuries in neurodegenerative diseases and aging-related risk conditions: a meta-analysis
Authors: Feng Feifei , Xu Haocheng , Sun Yu , Zhang Xin , Li Nan , Sun Xun , Tian Xin , Zhao Renqing 
Published: July 2023

IntroductionNeurodegenerative diseases often cause motor and cognitive deterioration that leads to postural instability and motor impairment, while aging-associated frailty frequently results in reduced muscle mass, balance, and mobility. These conditions increase the risk of falls and injuries in these populations. This study aimed to determine the effects of exercise on falls and consequent injuries among individuals with neurodegenerative diseases and frail aging people.MethodsElectronic database searches were conducted in PubMed, Cochrane Library, SportDiscus, and Web of Science up to 1 January 2023. Randomized controlled trials that reported the effects of exercise on falls and fall-related injuries in neurodegenerative disease and frail aging people were eligible for inclusion. The intervention effects for falls, fractures, and injuries were evaluated by calculating the rate ratio (RaR) or risk ratio (RR) with 95% confidence interval (CI).ResultsSixty-four studies with 13,241 participants met the inclusion criteria. Exercise is effective in reducing falls for frail aging people (RaR, 0.75; 95% CI, 0.68–0.82) and participants with ND (0.53, 0.43–0.65) [dementia (0.64, 0.51–0.82), Parkinson’s disease (0.49, 0.39–0.69), and stroke survivors (0.40, 0.27–0.57)]. Exercise also reduced fall-related injuries in ND patients (RR, 0.66; 95% CI, 0.48–0.90) and decreased fractures (0.63, 0.41–0.95) and fall-related injuries (0.89, 0.84–0.95) among frail aging people. For fall prevention, balance and combined exercise protocols are both effective, and either short-, moderate-, or long-term intervention duration is beneficial. More importantly, exercise only induced a very low injury rate per participant year (0.007%; 95% CI, 0–0.016) and show relatively good compliance with exercise (74.8; 95% CI, 69.7%–79.9%).DiscussionExercise is effective in reducing neurodegenerative disease- and aging-associated falls and consequent injuries, suggesting that exercise is an effective and feasible strategy for the prevention of falls.
The efficacy and safety in radioactive iodine refractory thyroid cancer patients treated with sorafenib
Authors: Ling Yuanna , Xiong Xiaoli , Luo Jiaxin , Zou Quanliang , Chen Pan , Pan Liqin , Long Man , Feng Huijuan , Ouyang Wei 
Published: July 2023

BackgroundSorafenib included in Chinese medical insurance is the earliest targeted drug for radioactive iodine refractory differentiated thyroid cancer (RR-DTC). This study is to further demonstrate the clinical efficacy and safety of sorafenib used in Zhujiang Hospital of Southern Medical University.MethodsRR-DTC patients treated at our Department of Nuclear Medicine in Zhujiang Hospital of Southern Medical University (October 2017–May 2020) were retrospectively analyzed. Treatment effects, progression-free survival (PFS), and adverse effects (AEs) during medication were evaluated.ResultsOf the 31 patients included, 26 patients were evaluated for efficacy with a median follow-up time of 17.5 months (4.0–51.0 months). The disease control rate (DCR) was 57.7% (n = 15) and the objective response rate (ORR) was 26.9% (n = 7). Most patients with disease control had thyroglobulin decreases of more than 60% (p = 0.004), ORRs were favorable in patients with lung metastasis and lung-only metastasis (p = 0.010 and 0.001, respectively). The PFS of the 26 patients analyzed was 16.5 months (95%CI: 14.41 –23.90 months). In the subgroup analysis, female, patients with lung-only metastasis, hand-foot skin syndrome (HFS), and thyroglobulin response ≥ 60% observed longer PFS (p = 0.038, 0.045, 0.035, and 0.000, respectively), while patients with bone metastasis had lower PFS (p = 0.035). The most common toxicity profile was HFS (93.5%), followed by diarrhea (83.9%), alopecia (74.2%). All the side effects were mainly grade 1–2. Grade 3–4 adverse reactions were more common in diarrhea and HFS.ConclusionsSorafenib has promising efficacy in RR-DTC, especially in patients with lung metastasis and lung-only metastasis. The AEs of sorafenib were generally mild, and the main AE was HFS.
Effects of Shenling Baizhu powder on intestinal microflora metabolites and liver mitochondrial energy metabolism in nonalcoholic fatty liver mice
Authors: Yao Zheng , Guo Jia , Du Bing , Hong Li , Zhu Ying , Feng Xiaoyi , Hou Yuanlu , Shi Anhua 
Published: July 2023

Background &amp; purposeNon-alcoholic fatty liver disease (NAFLD) is characterised by the excessive accumulation of triglycerides in the liver. Shenling Baizhu powder (SLBZP) is formulated from various natural medicinal plants that protect the liver and are used to treat intestinal diseases. SLBZP improves the symptoms of NAFLD. However, its mechanism of action remains unclear. Herein, we investigated the ameliorative effect of SLBZP on model mice with high-fat-diet (HFD)-induced NAFLD. Additionally, we evaluated the impact of SLBZP on the intestinal flora and its metabolites and mitochondrial energy metabolism in NAFLD.MethodsWe used HFD to establish a mouse model of NAFLD. Different drug interventions were administered. We measured serum biochemical indices. Liver sections were visualised with hematoxylin–eosin and oil red O staining. 16S rDNA amplicon sequencing technology was used to analyse the diversity and abundance of the intestinal flora. Short-chain fatty acids (SCFAs) in the intestinal contents were detected using GC-MS. Liver tissue was sampled to detect mitochondrial membrane functional indices. Western blotting was used to determine the levels of mitochondrial pathway-related proteins, namely, uncoupling protein 2 (UCP2), adenosine monophosphate-activated protein kinase (AMPK) and inhibitory factor 1 (IF1) of F1Fo ATP synthesis/hydrolase, in the liver.ResultsThe spleen-invigorating classic recipe of SLBZP reduced liver lipid deposition in mice with HFD-induced NAFLD. Additionally, SCFAs produced by intestinal flora metabolism regulated the UCP2/AMPK/IF1 signalling pathway involved in liver mitochondrial energy metabolism to improve the liver mitochondrial membrane permeability, respiratory state and oxidative phosphorylation efficiency of mice with NAFLD. Finally, SLBZP increased the liver ATP level.ConclusionOur results suggest that the therapeutic effect of SLBZP on NAFLD is related to the regulation of hepatic mitochondrial energy metabolism by intestinal flora and its metabolites and is possibly associated with the UCP2/AMPK/IF1 signalling pathway.
Genomic surveillance of genes encoding the SARS-CoV-2 spike protein to monitor for emerging variants on Jeju Island, Republic of Korea
Authors: Ha Young-Ran , Kim Hyun-Jeong , Park Jae-Sung , Chung Yoon-Seok 
Published: July 2023

IntroductionThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has been fueled by new variants emerging from circulating strains. Here, we report results from a genomic surveillance study of SARS-CoV-2 on Jeju Island, Republic of Korea, from February 2021 to September 2022.MethodsA total of 3,585 SARS-CoV-2 positive samples were analyzed by Sanger sequencing of the gene encoding the spike protein before performing phylogenetic analyses.ResultsWe found that the Alpha variant (B.1.1.7) was dominant in May 2021 before being replaced by the Delta variant (B.1.617.2) in July 2021, which was dominant until December 2021 before being replaced by the Omicron variant. Mutations in the spike protein, including N440K and G446S, have been proposed to contribute to immune evasion, accelerating the spread of Omicron variants.DiscussionOur results from Juju Island, Republic of Korea, are consistent with and contribute to global surveillance efforts crucial for identifying new variants of concern of SARS-CoV-2 and for monitoring the transmission dynamics and characteristics of known strains.