bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring clients’ responses to changing pronoun use from second person (you) to first person (I) during therapy: A constructivist qualitative approach
Authors: Priest Alan , Hollins Martin Caroline J. , Bager Charleson Sofie 
Published: September 2023

AbstractBackgroundPersonal pronouns like ‘I’, ‘me’ or ‘mine’ are inextricably linked with ownership, with one key benefit of a counsellor inviting a client to consider their pronoun use being an invitation to change their awareness and understanding of a situation.ObjectiveTo gain greater understanding of the impact of inviting clients to use first person pronoun ‘I’, in place of second ‘you’ during therapy and its effects upon the client and therapeutic process.MethodA constructivist qualitative approach using exploratory thematic analysis that engaged one‐to‐one counselling and follow‐up interviews was used. Participants (n = 11) were clients who had been referred for counselling via primary care with problems like depression, relationship break‐up and/or stress.FindingsSeveral themes were identified in the data: (1) potential discomfort from switching to first position; (2) awareness increased; (3) avoidance of taking responsibility recognised; (4) depersonalisation of events; (5) initiating change; and (6) effects on sense of self. Comments illustrate that reframing pronouns into first person removes distance between client emotions and problems, which provides them with an opportunity for development.DiscussionClients can be affected in productive ways when counsellors encourage them to alter their pronoun use during therapy. Through the use of reflection, the counsellor can work with their client to explore more fully their attributions of responsibility within situations that are discussed.
Construction of Naphthalenediimide Lanthanide(III)‐MOFs and Composites Incorporated Electron‐Rich Pyrene Derivative as Multifunctional Fluorescence Sensing for Nitro Aromatic Compounds and Aldehydes
Authors: Huo Rong , Zhang Ting , Zeng Guang , Wang Chen , Xing Yong Heng , Bai Feng Ying 
Published: September 2023

Comprehensive SummaryThe development of host‐guest MOF luminescent composites has attracted considerable attention. However, it is still a challenge to reasonably design large scale conjugated polycarboxylic acids metal‐organic framework (MOF) and modulate donor‐acceptor interaction. Herein, a series of isostructural 3D porous lanthanide MOF [Ln2(BINDI)0.5(NO3)(DMA)(H2O)]∙DMA∙2.5H2O (Ln = La (1), Ce (2), Pr (3) and Nd (4); H4BINDI (N,N’‐bis(5‐isophthalic acid)‐1,4,5,8‐naphthalenediimide) were synthesized. Considering the electron‐deficient performances of Ln‐BINDI MOFs, D‐A type composites Ln‐MOFs (1—4@H4TBAPy) were prepared via the incorporation of electron‐rich H4TBAPy (1,3,6,8‐tetrakis(p‐benzoic acid) pyrene), which more improved the luminescence performance of complexes 1—4 and can be used as fluorescence sensors for the detection of nitro compounds and aldehydes. High sensitivity of 1@H4TBAPy towards pNBA, pNA PNP, DNP, and TNP could be achieved through hydrogen bond interactions between MOF and analytes, as well as the π‐π interaction between H4TBAPy and the naphthalene ring of BINDI, thus the fluorescence quenching efficiency of 1@H4TBAPy was better than that of the complex 1. In addition, it is found that 1@H4TBAPy has high selectivity and sensitivity to aromatic aldehyde SA, 5‐Mesal and HMBA. Such strategy to enhance the emission of NDI based Ln‐BINDI MOFs, will open up an avenue to obtain more fluorescent MOFs for sensing.
Insulin signaling promotes neurogenesis in the brain of adult zebrafish
Authors: Gence Laura , Fernezelian Danielle , Meilhac Olivier , Rastegar Sepand , Bascands Jean‐Loup , Diotel Nicolas 
Published: September 2023

AbstractInsulin is a peptide hormone that plays a central role in the regulation of circulating blood glucose in vertebrates, including zebrafish. Increasing evidence has demonstrated the important role of insulin in many brain functions. In zebrafish, two insulin receptor genes (insra and insrb) have been identified. However, their biodistribution in the adult brain as well as their cell‐specific expression pattern has not been well described. Using gene expression analysis, in situ hybridization and transgenic fish, we confirmed the expression of insra, insrb, and irs1 (insulin receptor substrate 1, the downstream effector of insulin receptor) in the brain of adult zebrafish and characterized their specific expression in neurons and neural stem cells (radial glia). After demonstrating that intracerebroventricular (ICV) injection resulted in the diffusion of the injected solution within the ventricular system, we analyzed the effect of insulin ICV injection on neurogenesis. We showed that insulin promotes ventricular cell proliferation 24 h postinjection. This neurogenic effect appeared to be independent of neuroinflammatory processes. Also, after a mechanical telencephalic stab‐wound injury, we highlighted the overexpression of irs1 gene 5 days postlesion notably in the ventricular zone where radial glial cells (RGCs) are localized, suggesting key roles of insulin signaling in regenerative processes. Finally, our results reinforced the expression of insulin‐related proteins in the brain of adult zebrafish, highlighting the potential role of insulin signaling on neurogenesis.
A comparison of ‘not just right experiences’ in obsessive–compulsive disorder, anxiety and depressive disorders and non‐clinical controls in China
Authors: Yang Lijuan , Chen Daning , Zhang Xiaodong , Huang Fangfang , Li Zhanjiang , Yang Xiangyun 
Published: September 2023

AbstractObjectiveThe aim of this study is to investigate the characteristics of ‘not just right experiences’ (NJREs) in patients with obsessive–compulsive disorder (OCD), anxiety disorders (ADs) or major depressive disorder (MDD), compared with those of healthy controls (HCs).MethodOne hundred adults with OCD, 86 adults with ADs, 57 adults with MDD and 60 HCs were enrolled in the study. The Not Just Right Experiences Questionnaire Revised (NJRE‐QR), Yale–Brown Obsessive–Compulsive Scale (Y‐BOCS), Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI) were used to evaluate clinical symptoms in patients with OCD, ADs or MDD. The Obsessive Belief Questionnaire‐44 (OBQ‐44) was used to evaluate OC beliefs in the OCD patients. The HCs only received assessment using the NJRE‐QR. Analysis of variance (ANOVA) and covariance (ANCOVA) were performed to compare the NJREs scores across the groups, while Pearson correlation and partial correlation analyses were used to examine the association between NJREs and other clinical features. The contribution of NJREs to predict OC symptoms was determined by multiple stratified linear regression.ResultsIndividuals with OCD had significantly higher scores for the number of NJREs than ADs, but not MDD. The severity of NJREs was also significantly higher in patients with OCD than those with MDD or ADs (F = 5.23 and F = 19.79, respectively, P < 0.01). All the clinical scores in the NJRE‐QR were significantly higher than those in the HC group. The number and severity of NJREs correlated significantly with the Y‐BOCS total score (r = 0.29 and r = 0.39, respectively, P < 0.01). NJREs showed an independent contribution to OC symptoms, which alone explained 8% of the variation (F = 16.49, ΔR2 = 0.08; P < 0.01).ConclusionNJREs are related closely to OC symptoms, with their severity discriminating between OCD patients and those with ADs or MDD. NJREs were more specific for OCD in the Chinese population and are therefore worthy of further study in the future.
Co3O4 Supported on β‐Mo2C with Different Interfaces for Electrocatalytic Oxygen Evolution Reaction
Authors: Zhang Jiaxin , Li Sisi , Liu Xiaohan , Zheng Haoquan , Zhang Wei , Cao Rui 
Published: September 2023

AbstractInvited for this month′s cover is the group of Rui Cao at Shaanxi Normal University. The image shows the interface between Co3O4 and β‐Mo2C can be regulated to boost the electrocatalytic performance of water oxidation. The Research Article itself is available at 10.1002/cssc.202300709.
Multistage Op Amp design space exploration by gm/ID sampling and symbolic design equations
Authors: Xie Qixu , Shi Guoyong 
Published: September 2023

SummaryMultiple‐stage complementary metal‐oxide‐semiconductor (CMOS) operational amplifiers (Op Amps) have been extensively studied in the literature; often, each new design reports several performance advancements over the existing ones. However, the design space boundaries of those new proposals were rarely explored. Predicting the design space boundary of a new circuit topology is usually challenging due to the dependency on many aspects of technical consideration regarding the process technology, sizing priority adopted in practice, and balancing of performance metrics on power, area, noise immunity, and so on. Knowing the design space boundary could be beneficial to a fair appraisal of new designs. In this paper, we propose a gm/ID‐based method for the design space exploration of multistage Op Amps. By introducing a sampling technique while taking advantage of the device grouping property with gm/ID, it is possible to explore the circuit performance boundary by combining approximate symbolic modeling and gm/ID table lookup. Due to the introduction of a fast performance evaluation method, a large ensemble of circuit sizing samples can be evaluated in parallel, by which an efficient data mining procedure could be incorporated to deduce the circuit samples that can achieve extremal performance at Pareto boundaries. The fidelity of this proposal has been validated via simulation program with integrated circuit emphasis (SPICE) . The sampling method is also compared with a multi‐objective genetic algorithm to show the superiority in capturing Pareto boundaries.
High‐performance healable plastics: Focusing topological structure design based on constitutional dynamic chemistry
Authors: Liu Tong , Wang Lin , Xu JianHua , Fu JiaJun 
Published: September 2023

AbstractOver the past three decades, significant efforts have been dedicated to developing polymeric materials with exciting healable ability; however, stiff and healable plastics with high glass transition temperatures (Tg) have received relatively less attention compared to their soft counterparts such as gels and elastomers due to the inherent trade‐off between mechanical robustness and dynamics. High‐performance plastics are irreplaceable in the fields of engineering and industry, making it a challenging yet urgent task to confer them with desired healable properties whilst maintaining high mechanical strength. In this review, we first present recent advances in the field of high‐performance healable plastics based on constitutional dynamic chemistry, from the perspective of different topological structures including linear‐, branched‐ and network types. Meanwhile, we also elaborate on various toughening strategies for existing healable plastics, mainly centered around molecular to micrometer scale modifications. Moreover, we also provide a detailed exposition of previous reports on the autonomously room‐temperature self‐healing plastics, which represent a groundbreaking development in the realm of advanced healable plastics. Eventually, we emphasize diverse functionalized healable plastics to illustrate their potential for practical implementation, and propose an outlook on the future development of healable plastics.image
Ictal and interictal SPECT with 99mTc‐HMPAO in presurgical epilepsy. II: Methodological considerations on hyper‐ and hypoperfusion
Authors: Prener Martin , Drejer Veronica , Ziebell Morten , Jensen Per , Madsen Camilla Gøbel , Olsen Svitlana , Thomsen Gerda , Pinborg Lars H. , Paulson Olaf B. 
Published: September 2023

AbstractObjectiveSingle‐photon emission computed tomography (SPECT) with the tracer 99mTc‐HMPAO is a method to visualize the cerebral hyperperfusion during an epileptic seizure and thus localize the epileptogenic zone and seizure propagation. Subtraction of interictal from Ictal SPECT Co‐registered to MRI (SISCOM) visualizes areas with relative increases in cerebral blood flow. The purpose of this retrospective study is to explore the added value of visualizing areas of hypoperfusion as well as hyperperfusion, so‐called reversed SISCOM.MethodsFifty‐six patients operated for epilepsy who had been investigated with SISCOM were included in the analysis. The patients were divided into two groups based on seizure duration after tracer injection, above or below 30 s. The preoperative SISCOM description was compared to the area of resection and given a concordance score. The 56 SISCOM were recalculated visualizing also areas of hypoperfusion and again compared to the site of resection using the same scale of concordance. The reversed SISCOM were categorized into three subgroups: “Altered Conclusion,” “Confirmed Conclusion,” and “Adds Nothing.” If an area of hyperperfusion had an area of hypoperfusion in close proximity, it was re‐interpreted as noise, thus possibly altering the conclusion. If the areas of hypoperfusion were in the opposite hemisphere it was interpreted as confirming factor. Further the concordance scores from conventional SISCOM and reversed SISCOM was compared to surgical outcome to explore the difference in sensitivity, positive predictive value (PPV), and odds ratio.ResultsIn approximately half of the cases reversed SISCOM added additional value, meaning either altered the conclusion or confirmed the conclusion. The sensitivity, PPV, and odds ratio was also better in the subgroup of long, >30 s seizure duration after injection, and got worse in the group with short, <30 s seizure duration after injection.SignificanceAdding reversed SISCOM performed better than conventional SISCOM at predicting good surgical outcome.
Effects of Acute and Subchronic Waterborne Thallium Exposure on Ionoregulatory Enzyme Activity and Oxidative Stress in Rainbow Trout (Oncorhynchus mykiss)
Authors: Nagel Andrew , Cuss Chad W. , Goss Greg G. , Shotyk William , Glover Chris N. 
Published: September 2023

Abstract
The mechanisms of acute (96-hour) and subchronic (28-day) toxicity of the waterborne trace metal thallium (Tl) to rainbow trout (Oncorhynchus mykiss) were investigated. Specifically, effects on branchial and renal ionoregulatory enzymes (sodium/potassium adenosine triphosphatase [ATPase; NKA] and proton ATPase) and hepatic oxidative stress endpoints (protein carbonylation, glutathione content, and activities of catalase and glutathione peroxidase) were examined. Fish (19–55 g) were acutely exposed to 0 (control), 0.9 (regulatory limit), 2004 (half the acute median lethal concentration), or 4200 (acute median lethal concentration) µg Tl L–1 or subchronically exposed to 0, 0.9, or 141 (an elevated environmental concentration) µg Tl L–1. The only effect following acute exposure was a stimulation of renal H+-ATPase activity at the highest Tl exposure concentration. Similarly, the only significant effect of subchronic Tl exposure was an inhibition of branchial NKA activity at 141 µg Tl L–1, an effect that may reflect the interaction of Tl with potassium ion handling. Despite significant literature evidence for effects of Tl on oxidative stress, there were no effects of Tl on any such endpoint in rainbow trout, regardless of exposure duration or exposure concentration. Elevated basal levels of antioxidant defenses may explain this finding. These data suggest that ionoregulatory perturbance is a more likely mechanism of Tl toxicity than oxidative stress in rainbow trout but is an endpoint of relevance only at elevated environmental Tl concentrations. Environ Toxicol Chem 2024;43:87–96. © 2023 SETAC.
Engineering the oleaginous yeast Yarrowia lipolytica to produce nutraceuticals: From metabolic design to industrial applications
Authors: Gu Yang , Lu Xueyao , Liu Tongkang , Song Yanjin , Sang Ellie , Ding Shuran , Liu Long , Xue Feng , Xu Peng 
Published: September 2023

AbstractThe oleaginous yeast, Yarrowia lipolytica, has garnered much attention and is gaining recognition as a potential industrial platform for nutraceutical production. The superior properties of Y. lipolytica include its transparent inherited background, broad substrate spectrum, and superior environmental tolerance. Specifically, advances in genetic tools and engineering strategies have further widened its applications in metabolic engineering and biomanufacturing. In this review, we summarized developments in synthetic biology and engineering strategies for constructing Y. lipolytica to produce nutraceuticals. We also proposed perspectives on the limitations and challenges in developing microbial Y. lipolytica factories.
Marang fruit (Artocarpus Odoratissimus) waste: A promising resource for food and diverse applications: A review of its current status, research opportunities, and future prospects
Authors: Alvarado Marjun C. 
Published: September 2023

AbstractMarang fruit is commonly found and available in various Southeast Asian regions, notably in countries such as Malaysia, the Philippines, and Indonesia. Marang fruit waste, despite its promising potential, remains underutilized in various applications. This review article explores the potential of Marang fruit waste as a valuable resource for various applications, with a focus on its utilization in the food industry, including seed flour, starch, snacks, and essential bioactive compounds. Beyond the food sector, the article also investigates its applications as biosorbents/adsorbents and an energy source. The study identifies promising research opportunities such as investigating its potential as a fuel source, as well as for the production of cellulose and nanocellulose which is now gaining relevant attention in various industries. However, the seasonal availability of Marang fruit and its limited distribution in specific Southeast Asian regions present challenges. This article aims to provide a comprehensive understanding of the current status, highlight the areas that require further investigation, and future prospects of Marang fruit waste, highlighting its significance as a sustainable resource with multifaceted applications.
Realizing high‐energy density for practical lithium–sulfur batteries
Authors: Fang Ruopian , Chen Ke , Sun Zhenhua , Hu Guangjian , Wang Da‐Wei , Li Feng 
Published: September 2023

AbstractLithium–sulfur (Li–S) batteries has emerged as a promising post‐lithium‐ion battery technology due to their high potential energy density and low raw material cost. Recent years have witnessed substantial progress in research on Li–S batteries, yet no high‐energy Li–S battery products have reached the market at scale. Achieving high‐energy Li–S batteries necessitates a multidisciplinary approach involving advanced electrode material design, electrochemistry, and electrode and cell engineering. In this perspective, we offer a holistic view of pathways for realizing high‐energy Li–S batteries under practical conditions. Starting with a market outlook for high‐energy batteries, we present a comprehensive quantitative analysis of the critical parameters that dictate the cell‐level energy density for a Li–S battery. Thereby we establish a protocol to expedite the integration of lab‐scale Li–S research results into practical cell. Furthermore, we underscore several key considerations for promotion of commercial viability of high‐energy Li–S batteries from the perspective of battery industrialization.
Identification of priority areas for water conservation in the Alto Iguaçu basin, Brazil
Authors: Zani Lucas Henrique Silvestrin , Lopes Tárcio Rocha , Damaceno Felippe Martins , Miranda Yara Campos , Kozak Caroline , Tartari Rodrigo 
Published: September 2023

Abstract
Geoprocessing tools are great allies in the management of water resources, permitting the evaluation of several factors integrated into a multicriteria analysis. This improves the interpretation of the behavior of water and soil in hydrographic basins, allowing the delimitation of priority areas for actions. The objective of this study was to prepare a map of priority areas for water conservation in the Alto Iguaçu basin through a multicriteria analysis, aiming to assist in the management of water resources in the region. The priority map for water conservation was prepared using the weighted linear combination (WLC) method, considering the weight added to the factors that were obtained by the analytic hierarchy process (AHP) method. The method successfully identified priority areas for water conservation, where 40.7% of the Alto Iguaçu watershed was considered High priority and Very High priority, a number consistent with regional characteristics. The multicriteria analysis proved to be a flexible and easy to implement methodology, which can help managers when considering the trade-offs among several factors. The implementation of water conservation actions in areas that have been classified as being of High and Very High priority can benefit the regional ecosystem by controlling erosion, regulating the flow of water, and thus conserving the quantity and quality of water in the basin and its downstream region, benefiting the population and regional economics. Integr Environ Assess Manag 2024;20:1087–1098. © 2023 SETAC
Key Points
The multicriteria analysis proved to be a flexible and easy-to-implement methodology, which can help managers when considering the trade-offs between several factors. The implementation of water conservation actions in areas that have been classified as High and Very High priority can benefit the entire regional ecosystem by controlling erosion and regulating the flow of water. Among the 10 criteria chosen for the analysis, erodibility, proximity to springs, slope, and proximity to rivers stand out, which together represent 65.78% of the total weight attributed to the factors; this demonstrates the importance of focusing on the minimization of the impacts of these factors.
Dense fine speckled nuclear immunofluorescence: A mildly reassuring antinuclear antibody pattern meriting consideration
Authors: Fijałkowska Aleksandra , Schwartz Robert A. , Woźniacka Anna 
Published: September 2023

AbstractIntroductionAntinuclear antibodies (ANAs) are regarded as a hallmark of connective tissue diseases (CTDs) and play a key role in their diagnosis, but the value of some particular antibodies in management of patients and the disease prognosis is controversial. The mechanism underlying the production of ANAs in CTDs, other chronic inflammatory conditions and even in healthy people, is not completely elucidated. Anti‐DFS70 antibodies connected with the dense fine speckled autoantigen of 70 kD, known as the lens epithelium‐derived growth factor p75, are a subgroup of ANAs. Their presence and coexistence with other antibodies and their clinical significance are the matter of debate.MethodsBased on literature data, the authors focused on current knowledge explaining the role of anti‐DFS70 antibodies in selected CTDs.ResultsHowever, the literature data is ambiguous and does not fully support the validity of the anti‐DFS70 assay for a specific CTD diagnosis. Most researchers claim that the presence of anti‐DFS70 as the only one usually exclude the diagnosis of CTD. Nevertheless, its coexistence with other ANAs is not an excluding factor but has predictive value due to more favorable course of CTD. Such situations may also suggest an enhanced risk of the development of a CTD in the future.ConclusionsAlthough more studies are needed in this field, it seems reasonable to ascertain the presence of anti‐DFS70 in routine clinical practice.