bluuebunny/crossref_metadata_2025_split huggingface dataset:
Elevated Temperature Wear Behavior of AZ91 Magnesium Alloy After Micro-Arc Oxidation in Single and Dual Phase Electrolytes
Authors: Selvi Ekin , Kaba Mertcan , Muhaffel Faiz , Serdar Vanlı Ali , Baydoğan Murat 
Published: March 2023

Abstract
Low wear resistance of AZ91 alloy is the main factor limiting its more common use in industrial applications. Therefore, the micro-arc oxidation (MAO) process is mostly applied to the alloy to improve its wear resistance at room temperature (RT). However, the effect of the MAO coating on the wear behavior at elevated temperatures was investigated in limited works. In this study, the MAO process was performed on an AZ91 alloy in single-phase (silicate-containing) and dual-phase (aluminate + phosphate containing) electrolytes, and its wear behavior was investigated at both RT and 200 °C compared to the bare alloy. The results showed that the wear resistance of the alloy could be significantly improved both at RT and 200 °C, and the silicate-based electrolyte provided a better wear resistance at both temperatures. The results also showed that the dominant wear mechanism was oxidation for the bare alloy, and brittle fracture for the MAO-treated alloys.
Moroccan Consumer Energy Consumption Itemsets and Inter-Appliance Associations Using Machine Learning Algorithms and Data Mining Techniques
Authors: Abassi Abdelfattah , Arid Ahmed , Benazza Hussain 
Published: March 2023

Abstract
The study aims to analyze the patterns of home appliance use and energy consumption among Moroccan consumers using the MORED dataset. Machine learning algorithms and data mining techniques are applied to understand consumer behavior in terms of energy usage. The results provide insights into the inter-appliance association and peak hours, which will be used to design an Energy Demand Management System (EDMS) for Moroccan buildings in the future. The purpose of this research is to support the development of an effective EDMS and to encourage end-user involvement in energy management in Morocco.
Pyroxenite melting at subduction zones
Authors: Bowman Emilie E. , Ducea Mihai N. 
Published: March 2023

AbstractArc magmatism is thought to be driven by peridotite melting in the mantle wedge. Yet pyroxenites are ubiquitous in the melting region beneath magmatic arcs. Because they typically have lower solidi temperatures and higher melt productivities compared to peridotite, pyroxenites likely play a significant role in magma generation. Here, we use the Zn/Fe ratios of a global database of Pliocene–Holocene primitive arc magmas to show that, as the crustal thickness of the overlying plate increases, so does the proportion of pyroxenite-derived melts relative to peridotite-derived melts. In fact, at arcs with crustal thicknesses &gt;40 km, the majority of magmas are sourced from pyroxenite. Major and trace element geochemistry of pyroxenite melts is consistent with derivation from mafic magmas frozen in the mantle en route to the surface. We hypothesize that, as the thickness of the continental crust increases, the mantle wedge is displaced toward higher pressures and cooler temperatures, thereby lowering the extent of peridotite melting and allowing magmas sourced from the pyroxeniteveined mantle to dominate the arc budget.
Level of pain catastrophising determines if patients with long-standing subacromial impingement benefit from more resistance exercise: predefined secondary analyses from a pragmatic randomised controlled trial (the SExSI Trial)
Authors: Clausen Mikkel Bek , Rathleff Michael Skovdal , Graven-Nielsen Thomas , Bandholm Thomas , Christensen Karl Bang , Hölmich Per , Thorborg Kristian 
Published: March 2023

ObjectiveThe primary aim was to investigate the effectiveness of adding more resistance exercise to usual care on pain mechanisms (including temporal summation, conditioned pain modulation (CPM) and local pain sensitivity) and pain catastrophising in people with subacromial impingement at 16 weeks follow-up. Second, to investigate the modifying effect of pain mechanisms and pain catastrophising on the interventions’ effectiveness in improving shoulder strength and disabilityMethods200 consecutive patients were randomly allocated to usual exercise-based care or the same plus additional elastic band exercise to increase total exercise dose. Completed add-on exercise dose was captured using an elastic band sensor. Outcome measures recorded at baseline, 5 weeks, 10 weeks and 16 (primary end point) weeks included temporal summation of pain (TSP) and CPM assessed at the lower leg, pressure pain threshold at the deltoid muscle (PPT-deltoid), pain catastrophising and the Shoulder Pain and Disability Index.ResultsAdditional elastic band exercise was not superior to usual exercise-based care in improving pain mechanisms (TSP, CPM and PPT-deltoid) or pain catastrophising after 16 weeks. Interaction analyses showed that pain catastrophising (median split) modified the effectiveness of additional exercises (effect size 14 points, 95% CI 2 to 25), with superior results in the additional exercise group compared with the usual care group in patients with less pain catastrophising.ConclusionAdditional resistance exercise added to usual care was not superior to usual care alone in improving pain mechanisms or pain catastrophising. Additional exercise was, however, superior in improving self-reported disability in patients with lower levels of pain catastrophising at baseline.Trial registration numberNCT02747251
Innovations in mutuality: challenges and learnings for the Universal Health Insurance Plan in Mali
Authors: Touré Laurence , Boivin Pauline , Diarra Yacouba , Diabaté Seydou , Ridde Valéry 
Published: March 2023

BackgroundMany Sahel countries in Africa are looking for solutions for universal health coverage (UHC). Mali is in the process of adopting the Universal Health Insurance Plan, which allows for the mutualisation of existing schemes. Its operationalisation requires numerous adjustments to the current mutualist proposal and innovations in the system. The study focuses on innovations experienced in mutuality and their conditions of scale for UHC in Mali.MethodsThis is qualitative research by multiple case studies. It is based on the collection of data by interviews (n=136), at a national and local level, on the analysis of documents (n=42) and a long field observation (7 months). The analytical framework concerns the dissemination and maintenance of health innovations (Greenhalghet al,2004).ResultThe analysis of this innovation shows an interest in the technical and institutional viability that determines its performance and scale-up. The procrastination and scepticism displayed at the highest level of the state and the international level, the reluctance, both financial and ideological, to renew the old mutualist proposal, penalise this Malian experiment.ConclusionThis innovation is a decisive step in ensuring the health coverage of Mali’s agricultural and informal sectors. The reform will need to be amplified and supported in the future to expect the scale-up of a cheaper, technically and institutionally more efficient system. Without a political intention to mobilise national resources and accept a fundamental paradigm shift in health financing, the search for the financial viability of mutuality may, again, be at the expense of the performance.
Postural stability in blepharospasm: the effects of dual-tasking and botulinum toxin therapy
Authors: Balal Mehmet , Demir Turgay , Erdem Miray , Demirkiran Meltem 
Published: March 2023

BackgroundBlepharospasm is a focal dystonia that presents as involuntary, intermittent, continuous contractions of the eyelids. Abnormal eyelid contractions in blepharospasm are expected to cause balance problems, but there is no clear information.ObjectiveThis study was designed to evaluate the effect of blepharospasm on postural stability (PS) in patients with blepharospasm. As a secondary endpoint, the efficacy of botulinum toxin type-A (BoNT-A) treatment on static balance in patients with blepharospasm was investigated.MethodsTwenty-four patients with blepharospasm receiving regular BoNT-A injections and 20 age-matched and sex-matched healthy controls were included in the study. All subjects were evaluated on a static posturography force platform performing four tasks (eyes open (EO), eyes closed (EC), tandem Romberg (TR) and verbal cognitive task (COGT)). Evaluations of the patients were repeated 4 weeks after the injection.ResultsPretreatment lateral and anterior–posterior sways, sway area and velocities of the sways were significantly higher in patients than controls during the COGT and TR (p<0.05). In the patient group, with EO and EC, a few parameters improved after BoNT-A injection. On the other hand, in the TR and COGT, most of the sway parameters and velocities improved significantly after treatment (p<0.05).ConclusionsBlepharospasm may cause functional blindness in patients. This study demonstrated that PS worsens in patients with blepharospasm under dual-task conditions. BoNT-A injection treats the disease itself and, thus, markedly improves PS under dual-task conditions in blepharospasm.
Women’s experiences with using patient-reported outcome and experience measures in routine perinatal care in the Netherlands: a mixed-methods study
Authors: Laureij Lyzette T , Depla Anne L , Kariman Shariva S , Lamain-de Ruiter Marije , Ernst -Smelt Hiske E , Hazelzet Jan Antonius , Franx Arie , Bekker Mireille N 
Published: March 2023

ObjectivesTo gain insight into the experiences of women with completing and discussing patient-reported outcome measures (PROM) and patient-reported experience measures (PREM), and tailoring their care based on their outcomes.DesignA mixed-methods prospective cohort study.SettingSeven obstetric care networks in the Netherlands that implemented a set of patient-centred outcome measures for pregnancy and childbirth (PCB set), published by the International Consortium for Health Outcomes Measurement.ParticipantsAll women, receiving the PROM and PREM questionnaires as part of their routine perinatal care, received an invitation for a survey (n=460) and an interview (n=16). The results of the survey were analysed using descriptive statistics; thematic inductive content analysis was applied on the data from open text answers and the interviews.ResultsMore than half of the survey participants (n=255) felt the need to discuss the outcomes of PROM and PREM with their care professionals. The time spent on completing questionnaires and the comprehensiveness of the questions was scored ‘good’ by most of the survey participants. From the interviews, four main themes were identified: content of the PROM and PREM questionnaires, application of these outcomes in perinatal care, discussing PREM and data capture tool. Important facilitators included awareness of health status, receiving personalised care based on their outcomes and the relevance of discussing PREM 6 months post partum. Barriers were found in insufficient information about the goal of PROM and PREM for individual care, technical problems in data capture tools and discrepancy between the questionnaire topics and the care pathway.ConclusionsThis study showed that women found the PCB set an acceptable and useful instrument for symptom detection and personalised care up until 6 months post partum. This patient evaluation of the PCB set has several implications for practice regarding the questionnaire content, role of care professionals and congruity with care pathways.
Is Nigeria on course to achieve universal health coverage in the context of its epidemiological and financing transition? A knowledge, capacity and policy gap analysis (a qualitative study)
Authors: Ogundeji Yewande Kofoworola , Tinuoye Oluwabambi , Bharali Ipchita , Mao Wenhui , Ohiri Kelechi , Ogbuoji Osondu , Orji Nneka , Yamey Gavin 
Published: March 2023

ObjectivesThis study aimed to assess Nigeria’s preparedness to finance and drive the universal health coverage (UHC) agenda within the context of changing health conditions and resource needs associated with the disease, demographic and funding transitions.Nigeria is undergoing transitions in the healthcare system that include a double burden of infectious and non-communicable diseases, and transition from concessional donor assistance towards domestic financing for health. These transitions will affect Nigeria’s attainment of UHC.Design and settingWe conducted a qualitative study, including semistructured interviews with relevant stakeholders at national and subnational levels in Nigeria. Data from the interviews were analysed using thematic analysis.ParticipantsOur study involved 18 respondents from government ministries, departments, and agencies, development partners, civil society organisations and academia.ResultsCapacity gaps identified by respondents included limited knowledge to implement health insurance schemes at subnational levels, poor information/data management to monitor progress towards UHC and limited communication and interagency collaboration between government agencies and ministries. Furthermore, participants in our study expressed those current policies driving major health reforms like the National Health Act (basic healthcare provision fund) appear adequate to support UHC advancement in theory, but policy implementation is a key challenge due to a lack of policy awareness, low government spending on health and poor evidence generation for information to support decisions.ConclusionOur study found major gaps in knowledge and capacity for UHC advancement in the context of Nigeria’s demographic, epidemiological and financing transitions. These included poor knowledge of demographic transitions, poor capacity for health insurance implementation at subnational levels, low government spending on health, poor policy implementation and poor communication and collaboration among stakeholders. To address these challenges, collaborative efforts are needed to bridge knowledge gaps and increase policy awareness through targeted knowledge products, improved communication and interagency collaboration.
Changing Agendas on Sleep, Treatment and Learning in Epilepsy (CASTLE) Sleep-E: a protocol for a randomised controlled trial comparing an online behavioural sleep intervention with standard care in children with Rolandic epilepsy
Authors: Al-Najjar Nadia , Bray Lucy , Carter Bernie , CASTLE Advisory Panel , Collingwood Amber , Cook Georgia , Crudgington Holly , Currier Janet , Dietz Kristina Charlotte , Hardy Will A S , Hiscock Harriet , Hughes Dyfrig , Morris Christopher , Roberts Deborah , Rouncefield-Swales Alison , Saron Holly , Spowart Catherine , Stibbs-Eaton Lucy , Tudur Smith Catrin , Watson Victoria , Whittle Liam , Wiggs Luci , Wood Eifiona , Gringras Paul , Pal Deb K 
Published: March 2023

IntroductionSleep and epilepsy have an established bidirectional relationship yet only one randomised controlled clinical trial has assessed the effectiveness of behavioural sleep interventions for children with epilepsy. The intervention was successful, but was delivered via face-to-face educational sessions with parents, which are costly and non-scalable to population level. The Changing Agendas on Sleep, Treatment and Learning in Epilepsy (CASTLE) Sleep-E trial addresses this problem by comparing clinical and cost-effectiveness in children with Rolandic epilepsy between standard care (SC) and SC augmented with a novel, tailored parent-led CASTLE Online Sleep Intervention (COSI) that incorporates evidence-based behavioural components.Methods and analysesCASTLE Sleep-E is a UK-based, multicentre, open-label, active concurrent control, randomised, parallel-group, pragmatic superiority trial. A total of 110 children with Rolandic epilepsy will be recruited in outpatient clinics and allocated 1:1 to SC or SC augmented with COSI (SC+COSI). Primary clinical outcome is parent-reported sleep problem score (Children’s Sleep Habits Questionnaire). Primary health economic outcome is the incremental cost-effectiveness ratio (National Health Service and Personal Social Services perspective, Child Health Utility 9D Instrument). Parents and children (≥7 years) can opt into qualitative interviews and activities to share their experiences and perceptions of trial participation and managing sleep with Rolandic epilepsy.Ethics and disseminationThe CASTLE Sleep-E protocol was approved by the Health Research Authority East Midlands (HRA)–Nottingham 1 Research Ethics Committee (reference: 21/EM/0205). Trial results will be disseminated to scientific audiences, families, professional groups, managers, commissioners and policymakers. Pseudo-anonymised individual patient data will be made available after dissemination on reasonable request.Trial registration numberISRCTN13202325.
Acupuncture in chemotherapy-induced dysgeusia (AcuDysg): study protocol of a randomised controlled trial
Authors: Huber Christine , Zhang Linxin , Schlaeppi Marc , Müller Twyla , Roll Stephanie , Voiss Petra , Barth Jürgen , Driessen Christoph , Witt Claudia M 
Published: March 2023

IntroductionDysgeusia is a common side effect of chemotherapy in patients with cancer, but to date, there is no effective treatment. Many patients with cancer request complementary medicine treatment in addition to their cancer treatments, and acupuncture is highly accepted for patients with cancer; however, evidence regarding the effectiveness of acupuncture for dysgeusia is scarce.The study investigates the effectiveness of an additional dysgeusia-specific acupuncture plus self-acupressure intervention compared with supportive acupuncture plus self-acupressure intervention alone for chemotherapy-induced dysgeusia in patients with cancer.Methods and analysisThis is a multicentre, randomised, controlled and two-armed parallel-group, single-blind trial involving 130 patients. Both groups will receive eight sessions of acupuncture treatment over a period of 8 weeks and will be trained to perform self-acupressure (eLearning combined with therapist instruction) at predefined acupressure points once a day during the whole treatment period. Patients in the control group will receive supportive routine care acupuncture and self-acupressure treatment only; in addition to this treatment, the intervention group will receive the dysgeusia-specific acupuncture and acupressure within the same treatment session. The primary outcome is the perceived dysgeusia over 8 weeks, measured weekly after the acupuncture treatment. Secondary outcomes include the indices from the objective taste and smell test, weight loss, perceived dysgeusia, fatigue, distress, nausea and vomiting, odynophagia, xerostomia and polyneuropathy, as well as quality of life at the different time points.Ethics and disseminationThe study has been approved by the Cantonal Ethics Committee (CEC) (Kanton Zürich Kantonale Ethikkommission) (approval no. KEK-ZH-Nr. 2020–01900). The results will be submitted to a peer-reviewed journal for publication.Trial registration numbersDRKS00023348, SNCTP000004128.
Impact of COVID-19 pandemic on the diagnosis of patients with skin cancer: a systematic review protocol
Authors: Mostafavi Zadeh Seyed Mostafa , Rezaei Yasaman , Barahimi Ahmadreza , Abbasi Ebrahim , Malekzadeh Roudabeh 
Published: March 2023

IntroductionThe COVID-19 pandemic has changed aspects of patient care in the many scheduled medical activities, restricted access to healthcare facilities, and affected the diagnosis and organisation of patients with other health problems, specifically skin cancer. Skin cancer, the uninhibited progress of atypical skin cells, happens with unrepaired DNA genetic faults that lead them to multiply and create malignant tumours. Currently, dermatologists perform skin cancer diagnosis based on their specialised experience using the results of pathological tests from the skin biopsy. Sometimes, some specialists advise sonography imaging to check the skin tissue as a non-invasive method. The outbreak has led to postponements in the treatment and diagnosis of patients with skin cancer, including diagnostic delays because of limitations of diagnostic capacities and delays in referring patients to the physician. The purpose of this review is to improve our understanding of the impact of the COVID-19 outbreak on the diagnosis of patients with skin cancer and conduct a scoping review to identify whether routine skin cancer diagnoses are affected by the persistent incidence of COVID-19.Methods and analysisThe structure of research was compiled using Population/Intervention/Comparison/Outcomes/Study Design and Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. First, we will find the main keywords to capture scientific studies related to the impact of the COVID-19 pandemic on the diagnosis of skin cancer: COVID-19 and skin neoplasms. To warrant sufficient coverage and identify potential articles, we will search the combination of four electronic databases PubMed/MEDLINE, Scopus, Web of Science and EMBASE, and ProQuest from 1 January 2019 until 30 September 2022. The screening, selection and data extraction of studies will be performed by two independent authors, who will then assessed the quality of the included studies according to Newcastle–Ottawa Scale.Ethics and disseminationAs this study will be a systematic review without human participants’ involvement, no formal ethical assessment is required. Findings will be presented at conferences related to this field and will be disseminated in a peer-reviewed journal.PROSPERO registration numberCRD42022361569.