bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diabetes and Untoward Outcomes after ACL Reconstruction
Authors: Sievers Dennis , Prentice Heather A. , Chung Joanie , Davis Anna , Maletis Gregory B. , Navarro Ronald A. 
Published: January 2025

Background Diabetes affects approximately 536.6 million adults worldwide and 32.2 million in the United States. Prior studies across multiple specialties have reported the presence of diabetes is associated with adverse outcomes following surgical operations. While several studies have identified diabetes as a risk factor for adverse outcomes following ACL reconstruction (ACLR), literature evaluating the relationship between diabetes status and outcomes after ACLR is lacking. Purpose We aimed to study surgical outcomes following primary ACLR among patients with diabetes compared to those without diabetes. Study Design Retrospective Cohort Study Methods We conducted a cohort study using data from an integrated healthcare system’s ACLR registry. Patients aged ≥12 receiving a primary unilateral ACLR were included (2005–2020). Preoperative diabetes status was the exposure of interest. The two primary outcomes were revision surgery and ipsilateral reoperation following primary ACLR, modeled using multivariable Cox proportional hazards regression that followed patients until an adverse event or loss to follow up. We also examined hospital readmission within 90 days post-surgery, modeled using logistic regression. All models compared patients with diabetes to those without diabetes, adjusting for age, gender, race, smoking status, body mass index, American Society of Anesthesiologist’s score, comorbid conditions, education level, income level, exercise, and graft type. Results There were 18,797 primary ACLR in the study sample with 383 (2.0%) occurring in patients with diabetes. The diabetes group exercised about 90 minutes less per week than the non-diabetes group. In unadjusted bivariate descriptive analyses, patients with diabetes had a lower rate of revision surgery (1.6% vs. 3.6%, p = 0.037) but a higher rate of ipsilateral reoperation (10.7% vs. 8.0%, p = 0.051). The 90-day readmission rate was higher among patients with diabetes compared to those without diabetes (1.8% vs. 0.7%, p = 0.016). However, after adjusting for covariates, these associations were no longer statistically significant. Conclusion After controlling for patient characteristics and other risk factors, the presence of diabetes was not associated with a higher risk of adverse events following primary ACLR.
Pengaruh Penyuluhan Manfaat Jus Wortel Untuk Mengatasi Dismenore Pada Remaja Putri Di Smp Swasta Al-Ihsan Mulia
Authors: Dwi Listiarini Utary , Nurrohmaton  , Lisma Nur 
Published: January 2025

Dismenore atau nyeri haid biasanya terjadi pada saat menstruasi. Menurunkan tingkat nyeri dismenorea dengan salah satu cara non farmakologi menggunakan obat tradisional adalah wortel. Tujuan Penelitian ini adalah untuk mengetahui pengaruh penyuluhan manfaat jus wortel terhadap dismenorea pada remaja putri. Penelitian ini menggunakan metode Quasi Eksperimental dengan one group pretest-posttest design. Populasi dalam penelitian ini adalah seluruh siswi kelas IX SMP SwastaAl-Ihsan Mulia Kecamatan Medan Helvetia Kota Medan sebanyak 22 orang. Teknik pengambilan sampel adalah menggunakan total population. Analisis data menggunakan analisis univariat dan analisis bivariat dengan uji Uji T Dependen (Paired Sampel T Test). Penelitian diketahui pengetahuan pada pre-test siswi dengan pengetahuan baik sebanyak 3 orang (13,6%), pengetahuan cukup sebanyak 13 orang (59,1%) dan pengetahuan kurang sebanyak 6 orang (27,3%) sedangkan pengetahuan pada post-test siswi dengan pengetahuan baik sebanyak 19 orang (86,4%) dan pengetahuan cukup sebanyak 3 orang (13,6%). Hasil uji bivariate diketahui nilai Sig. (2-tailed) sebesar 0,000 < 0,05. Ada pengaruh penyuluhan tentang manfaat jus wortel terhadap dismenorea pada remaja putri terhadap pengetahuan siswi Kelas IX di SMP Swasta Al-Ihsan Mulia Kecamatan Medan Helvetia Kota Medan. Disarankan kepada remaja putri agar lebih aktif dalam mencari informasi yang tepat pada media informasi, tentang dismenore dan cara penanganan non farmakologi serta manfaat jus wortel terhadap dismenorea.
Pengaruh Pengungkapan Corporate Social Responsibility (CSR Disclosure) Terhadap Nilai Perusahaan Yang Terdaftar Di Bursa Efek Indonesia Periode 2019 - 2023
Authors: La Ode Risman  , Mulyati Akib  
Published: January 2025

Penelitian ini bertujuan untuk mengetahui seberapa besar pengaruh pengungkapan Corporate Social Responsibility terhadap nilai perusahaan. Populasi dalam penelitian ini adalah perusahaan pertambangan Sektor Energi yang terdaftar di Bursa Efek Indonesia pada periode 2019-2023. Indeks Corporate Social Responsibility mengikuti pedoman dari Global Reporting Initiative (GRI)-G4. Tobin’s Q digunakan sebagai proksi untuk nilai perusahaan. Pemilihan sampel dilakukan dengan metode purposive sampling. Metode analisis data yang digunakan dalam penelitian ini adalah analisis regrsi data panel dengan jumlah sampel sebanyak 11 perusahaan. Hasil penelitian ini menunjukkan bahwa pengungkapan Corporate Social Responsibility tidak berpengaruh terhadap nilai perusahaan.
Employee Engagement And Leader-Member Exchange Form Organizational Commitment And Organizational Citizenship Behavior. Can It Be Achieved For Employees Who Work While Studying?
Authors: Hayati Diana , Rifani Ahmad 
Published: January 2025

This study aims to explore the relationship between employee engagement (EE) and leader-member exchange (LMX) in shaping organizational Commitment (OC) and organizational citizenship behavior (OCB) among employees who work while studying. Data was collected from 291 respondents who had worked for at least 1 year in various sectors. Using the Structural Equation Modeling approach, the results of the study showed that employees who had a high level of engagement and good relationships with leaders tended to show a higher commitment to the organization and a higher OCB. Based on the results of the study, five direct influences produce positive and significant numbers, namely EE against OC, EE against OCB, LMX against OC, LMX against OCB and OC against OCB. The indirect influence of EE on OCB through OC also produces a positive and significant, meaning that OC plays a role in mediating the influence of EE on OCB. The indirect impact of LMX variables on OCB through OC is also positive and significant, meaning that OC mediates the influence of LMX on OCB.
The Rockefeller Foundation’s “Public Stewardship of Private Providers in Mixed Health Systems”: A Point-by-Point Critique
Authors: Schuftan Claudio , Unger Jean Pierre 
Published: January 2025

The 2010 World Health Assembly (WHA) tabled, but did not manage to discuss, a resolution on regulating the private health care sector. 1 With hindsight, it seems fitting to thoroughly review an earlier 2008 Rockefeller Foundation (RF) report on the same issue: “Public Stewardship of Private Providers in Mixed Health Systems.” The key weakness of the RF document – and also of the above WHA draft resolution – is that both fail to provide the necessary empirical evidence to show that better ‘stewarding’ regulation in low and middle income countries (LMICs) has worked to provide quality, accessible, and affordable health care for all in mixed public-private health systems. In this article, we voice our skepticism about whether public stewardship can work in mixed systems in LMICs. Moreover, the RF report does not address the access to quality health care from a human rights perspective. The right to quality health care is simply overlooked. The report prescribes “new solutions” to well known regulatory problems and fails to offer any evidence of their benefit. It argues that regulation of mixed public-private health systems can be successful without providing any evidence even at local level. This lack of evidence is striking since we have a good 20 years of experience with such regulation. We conclude that a) private providers will never be effectively controlled in LMICs with regulation alone, and b) that the report reflects RF’s ideological bias against single payer, universal coverage public health care systems. We argue that the “regulation alternative” is simply not a substitute for strengthening the public sector. Many of the measures proposed by the Rockefeller Foundation report are not necessarily wrong, but they are applied to a private sector enjoying an established position that has given them access to deliver health care as a privilege and not as a right. Indeed, we remain convinced that if some of the proposed measures were applied to the public health sector with adequate long-term government and donor financing, they would go a longer way to achieve Health Care For All. The past experiences of Costa Rica and Sri Lanka suggest that LMICs private health markets have only effectively been controlled in countries where the public sector was effective in competing with the private sector. A well organized and funded public health system, delivering comprehensive health care (not restricted to vertical disease control programs and not treating health as a commodity) is the only alternative to reign-in the excesses of LMIC private providers in mixed health systems.
Workplace Harassment (Mobbing) and Fibromyalgia
Authors: Fuentes Valdivieso Rocío , Lara Padilla Eleazar 
Published: January 2025

The present study is the result of interdisciplinary research on the relationship between workplace harassment (or mobbing) and fibromyalgia (FM). Mobbing can cause emotional trauma due to the intense suffering that it provokes in the individuals who experience workplace harassment for a prolonged and recurrent manner. FM is a progressive disease that presents mainly in women and is characterized by generalized, debilitating pain, along with fatigue that does not resolve with rest. Because of studies suggesting an association between these two phenomena, we examined these two conditions in the context of our own country (Mexico).

The purpose of this study is to answer two questions:

1)	Can workplace relationships exacerbate a pre-existing case of FM?

2)	Can workplace harassment cause the development of a disease such as FM?
Epidemiology and Damage Accrual of Systemic Lupus Erythematosus in Central Sweden: A Single‐Center Population‐Based Cohort Study Over 14 Years From Östergötland County
Authors: Arkema Elizabeth V. , Saleh Muna , Simard Julia F. , Sjöwall Christopher 
Published: July 2023

ObjectiveVariations in prevalence and incidence of systemic lupus erythematosus (SLE) within a geographically defined area of central Sweden over a time period of 14 years were examined. Longitudinal differences in disease activity, laboratory test results, and damage accrual were investigated.MethodsAdults (aged ≥18 years) residing in Östergötland County between 2008 and 2021 (mean adult population: 357,000 citizens) with confirmed SLE were identified and followed prospectively until death, December 31, 2021, or emigration. We estimated annual incidence per 100,000 inhabitants stratified by sex and age. Linear regression with year of diagnosis as the outcome assessed whether each clinical measurement at diagnosis varied over time.ResultsPrevalence on December 31, 2021, was 71.5 of 100,000 (87% female). One hundred twenty‐six new cases were identified during the study period, yielding a mean annual incidence of 3.0 of 100,000 inhabitants; this was higher in females (4.8/100,000) than in males (1.2/100,000). Mean age at diagnosis was 43.7 years (SD 17.3). Age at diagnosis and disease activity measures increased over the calendar year of diagnosis (P < 0.05) whereas disease manifestations, including lupus nephritis, did not vary significantly. Accrual of organ damage was demonstrated over time since diagnosis and stratified by sex, lupus nephritis, and corticosteroid‐related damage. Approximately 40% developed damage within 5 years.ConclusionSLE prevalence and incidence estimates remained constant over 14 years, and disease phenotypes at SLE onset were similar. SLE was diagnosed also among older individuals with a smaller female‐to‐male ratio. Estimates of prevalence and incidence were comparable to previous Scandinavian reports but lower than observed in registry data from the US and the UK.
Risk as a pattern over time: Delineation of time‐dependent risk factors in biological, psychological, and social variables in cancer patients
Authors: Knefel Matthias , Zeilinger Elisabeth L. , Lubowitzki Simone , Krammer Katharina , Unseld Matthias , Bartsch Rupert , Fuereder Thorsten , Jäger Ulrich , Kiesewetter Barbara , Krauth Maria , Raderer Markus , Staber Philipp B. , Valent Peter , Gaiger Alexander 
Published: July 2023

AbstractBackgroundSurvival in cancer patients is associated with a multitude of biological, social, and psychological factors. Although it is well established that all these factors add to overall mortality, it is not well understood how the predictive power of these parameters changes in a comprehensive model and over time.MethodsPatients who attended the authors’ outpatient clinic were invited to participate. The authors followed 5180 mixed cancer patients (51.1% female; mean age, 59.1 years [SD = 13.8]) for up to 16 years and analyzed biological (age, sex, cancer site, anemia), psychological (anxiety, depression), and social variables (marital status, education, employment status) potentially predicting overall survival in a Cox proportional hazards model.ResultsThe median survival time for the entire sample was 4.3 years (95% confidence interval, 4.0–4.7). The overall survival probabilities for 1 and 10 years were 76.8% and 38.0%, respectively. Following an empirical approach, the authors split the time interval into five periods: acute, subacute, short‐term, medium‐term, and long‐term. A complex pattern of variables predicted overall survival differently in the five periods. Biological parameters were important throughout most of the time, social parameters were either time‐independent predictors or tended to be more important in the longer term. Of the psychological parameters, only depression was a significant predictor and lost its predictive power in the long‐term.ConclusionsThe findings of this study allow the development of comprehensive patient‐specific models of risk and resilience factors addressing biopsychosocial needs of cancer patients, paving the way for a personalized treatment plan that goes beyond biomedical cancer care.
Hidden Markov movement models reveal diverse seasonal movement patterns in two North American ungulates
Authors: Paterson John Terrill , Johnston Aaron N. , Ortega Anna C. , Wallace Cody , Kauffman Matthew 
Published: July 2023

AbstractAnimal movement is the mechanism connecting landscapes to fitness, and understanding variation in seasonal animal movements has benefited from the analysis and categorization of animal displacement. However, seasonal movement patterns can defy classification when movements are highly variable. Hidden Markov movement models (HMMs) are a class of latent‐state models well‐suited to modeling movement data. Here, we used HMMs to assess seasonal patterns of variation in the movement of pronghorn (Antilocapra americana), a species known for variable seasonal movements that challenge analytical approaches, while using a population of mule deer (Odocoileus hemionus), for whom seasonal movements are well‐documented, as a comparison. We used population‐level HMMs in a Bayesian framework to estimate a seasonal trend in the daily probability of transitioning between a short‐distance local movement state and a long‐distance movement state. The estimated seasonal patterns of movements in mule deer closely aligned with prior work based on indices of animal displacement: a short period of long‐distance movements in the fall season and again in the spring, consistent with migrations to and from seasonal ranges. We found seasonal movement patterns for pronghorn were more variable, as a period of long‐distance movements in the fall was followed by a winter period in which pronghorn were much more likely to further initiate and remain in a long‐distance movement pattern compared with the movement patterns of mule deer. Overall, pronghorn were simply more likely to be in a long‐distance movement pattern throughout the year. Hidden Markov movement models provide inference on seasonal movements similar to other methods, while providing a robust framework to understand movement patterns on shorter timescales and for more challenging movement patterns. Hidden Markov movement models can allow a rigorous assessment of the drivers of changes in movement patterns such as extreme weather events and land development, important for management and conservation.
Phasmid species that inhabit colder environments are less likely to have the ability to fly
Authors: Emberts Zachary 
Published: July 2023

AbstractA vast majority of insects can fly, but some cannot. Flight generally increases how far an individual can travel to access mates, enables the exploitation of additional food resources, and aids in predator avoidance. Despite its functional significance, much remains unknown about the factors that influence the evolution of flight. Here, I use phylogenetic comparative methods to investigate whether average annual temperature or wind speed, two components of the flying environment, is correlated with the evolution of flight using data from 107 species of stick and leaf insects (Insecta: Phasmatodea). I find no association between wind speed and flying ability in this clade. However, I find that colder temperatures are associated with the lack of flying ability. This pattern may be explained by the additional metabolic costs required for insects to fly when it is cold. This finding contradicts previous patterns observed in other insect groups and supports the hypothesis that cold temperatures can influence the evolution of flight.
Ex‐SPECTing success: Predictors of successful SPECT radiotracer injection during presurgical video‐EEG admissions
Authors: Cosentino Carmela , Al Maawali Said , Wittayacharoenpong Thanomporn , Tan Tracie , Au Yong Hue Mun , Shakhatreh Lubna , Chen Zhibin , Beech Paul , Foster Emma , O'Brien Terence J. , Kwan Patrick , Neal Andrew 
Published: July 2023

AbstractObjectivesTo determine predictors of successful ictal single photon emission computed tomography (SPECT) injections during Epilepsy Monitoring Unit (EMU) admissions for patients undergoing presurgical evaluation for drug‐resistant focal epilepsy.MethodsIn this retrospective study, consecutive EMU admissions were analyzed at a single center between 2019 and 2021. All seizures that occurred during the admission were reviewed. “Injectable seizures” occurred during hours when the radiotracer was available. EMU‐level data were analyzed to identify factors predictive of an EMU admission with a successful SPECT injection (successful admission). Seizure‐level data were analyzed to identify factors predictive of an injectable seizure receiving a SPECT injection during the ictal phase (successful injection). A multivariate generalized linear model was used to identify predictive variables.Results125 EMU admissions involving 103 patients (median 37 years, IQR 27.0–45.5) were analyzed. 38.8% of seizures that were eligible for SPECT (n = 134) were successfully injected; this represented 17.4% of all seizures (n = 298) that occurred during admission. Unsuccessful admissions were most commonly due to a lack of seizures during EMU‐SPECT (19.3%) or no injectable seizures (62.3%). Successful EMU‐SPECT was associated with baseline seizure frequency >1 per week (95% CI 2.1–3.0, P < 0.001) and focal PET hypometabolism (95% CI 2.0–3.7, P < 0.001). On multivariate analysis, the only factor associated with successful injection was patients being able to indicate they were having a seizure to staff (95% CI 1.0–4.4, P = 0.038).SignificanceCompleting a successful ictal SPECT study remains challenging. A baseline seizure frequency of >1 per week, a PET hypometabolic focus, and a patient's ability to indicate seizure onset were identified as predictors of success. These findings may assist EMUs in optimizing their SPECT protocols, patient selection, and resource allocation.
Single‐ vs. combined‐category preference assessments for edible, leisure, and social‐interaction stimuli
Authors: Goldberg Nicole M. , Roscoe Eileen M. , Newman Zoe A. , Sedano Angelica J. 
Published: July 2023

AbstractA concern when conducting combined‐category preference assessments is the potential for displacement effects, a shift in the preference ranking from highly preferred to moderately or less preferred for stimuli in two of three stimulus categories (e.g., edible, leisure, or social‐interaction). In this study, we evaluated potential displacement effects in combined‐category arrays of edible, leisure, and social‐interaction stimuli for five individuals with autism. First, single‐category paired‐stimulus preference assessments were implemented to identify two highly preferred stimuli from each category. When these stimuli were included in a combined‐category preference assessment, displacement effects were observed for three of five participants. During a subsequent reinforcer assessment, stimuli identified as less preferred in the combined‐category preference assessment functioned as reinforcers for two participants. Additionally, although social interaction was not identified as highly preferred for three of the five participants, it functioned as a reinforcer for four participants.
Altered dynamic functional network connectivity and topological organization variance in patients with white matter hyperintensities
Authors: Huang Chaojuan , Zhou Xia , Ren Mengmeng , Zhang Wei , Wan Ke , Yin Jiabin , Li Mingxu , Li Zhiwei , Zhu Xiaoqun , Sun Zhongwu 
Published: July 2023

AbstractWhite matter hyperintensities (WMHs) of presumed vascular origin are important imaging biomarkers of cerebral small vessel disease (CSVD). Previous studies have verified abnormal functional brain networks in CSVD. However, most of these studies rely on static functional connectivity, and only a few focus on the varying severity of the WMHs. Hence, our study primarily explored the disrupted dynamic functional network connectivity (dFNC) and topological organization variance in patients with WMHs. This study included 38 patients with moderate WMHs, 47 with severe WMHs, and 68 healthy controls (HCs). Ten independent components were chosen using independent component analysis based on resting‐state functional magnetic resonance imaging. The dFNC of each participant was estimated using sliding windows and k‐means clustering. We identified three reproducible dFNC states. Among them, patients with WMHs had a significantly higher occurrence in the sparsely connected State 1, but a lower occurrence and shorter duration in the positive and stronger connected State 3. Regarding topological organization variance, patients with WMHs showed higher variance in local efficiency but not global efficiency compared to HCs. Among the WMH subgroups, patients with severe WMHs showed similar but more obvious alterations than those with moderate WMHs. These altered network characteristics indicated an imbalance between the functional segregation and integration of brain networks, which was correlated with global cognition, memory, executive functions, and visuospatial abilities. Our study confirmed aberrant dFNC state metrics and topological organization variance in patients with moderate‐to‐severe WMHs; thus, it might provide a new pathway for exploring the pathogenesis of cognitive impairment.