bluuebunny/crossref_metadata_2025_split huggingface dataset:
Web accessibility of Indian cultural heritage information: an analytical study of museum websites
Authors: Pandey Rahul , Kumar Vinit 
Published: March 2023

PurposeThis paper compares the web accessibility of Indian museum websites assessing the level of compliance to the Web Content Accessibility Guidelines 2.1 (WCAG 2.1). The study aims to assess the accessibility of Indian museum websites in terms of their severity.Design/methodology/approachThe accessibility evaluation of 11 Indian museum websites was conducted using Siteimprove Accessibility Checker (SAC), an automated website testing tool.FindingsThe study results indicate that the mean conformance score for the Indian museum websites for level A was 19.27, while for level AA and AAA, it came out to be 2.63 and 4.09, respectively, with the highest severity scores for error (16.3) followed by review (5.81) criteria and warning (3.81). The major findings indicate that the websites of Indian museums poorly conform to web accessibility guidelines.Practical implicationsThe study's findings will assist the museum's website creators, managers and administrators in determining the level of conformity as per standard accessibility guidelines helping them make strategic decisions to improve the accessibility.Originality/valueMost of the studies available in the field of website accessibility range from the web accessibility of educational institutions, tourism websites, municipal websites and ministerial websites, but there are very few studies investigating the accessibility of museum websites. A quantitative evaluation of different aspects of accessibility was conducted in the study, which can pave the way for the better design of web sites by addressing deficiencies.
Examining the role of personality traits in guestroom technologies
Authors: Demirciftci Tevfik , Bilgihan Anil , Erdem Mehmet , Baloglu Seyhmus 
Published: March 2023

PurposeThis study aimed to identify distinctive characteristics of hotel guests and understand their perception of guestroom technologies (GRTs) in hotels by utilizing the theory of consumer innovativeness and the social influence theory.Design/methodology/approachThe data were collected from 268 hotel guests. The K-means clustering algorithm was employed to identify participants based on their views on the significance of technologies provided in guest rooms. A multivariate analysis of variance was applied to investigate if there were significant differences among clusters regarding social influence on hotel bookings, technology innovativeness and technology expertise and knowledge.FindingsTwo clusters were identified: technology compassionates and casual users of technology. Findings revealed that technology compassionates are more influenced by their friends when booking a hotel compared to casual users of technology. The ability to link up multiple wireless mobile devices, accessible outlets and mobile websites were the most critical GRTs for technology compassionates.Practical implicationsTechnology should be considered a crucial part of the hotel guest experience. Hoteliers ought to continue investing in smart technologies to improve their guests' experiences. GRTs can reduce overhead staff costs while giving guests more control over their stay by utilizing everyday items like smartphones and offering them more power over their lodging experience.Originality/valueThis study advances the existing literature on GRTs by identifying which GRTs produce the most customer satisfaction. Moreover, this study explores the impact of social influence, innovativeness as a personality trait and having expert knowledge of technologies on preferences for GRTs.
Increasing global mindset through collaborative online international learning (COIL): internationalizing the undergraduate international business class
Authors: Garcia Fernando , Smith Stephen Ray , Burger Amy , Helms Marilyn 
Published: March 2023

Purpose
This study aims to provide a case example of two partner institutions and business faculty who creatively used a collaborative online international learning (COIL) experience during the height of the COVID-19 pandemic and transition to online learning to internationalize an undergraduate business class and use existing technology to offer a case study project to further students’ global mindset.

Design/methodology/approach
Using open-ended qualitative comments from an American college and a Peruvian university, researchers uncovered key themes from a virtual COIL-based learning experience offered as part of an international business class.

Findings
Student end-of-course evaluation comments from both countries validated the success of the learning experience and value of working together with other students and faculty in a virtual setting.

Research limitations/implications
Areas for future research are provided to extend these initial exploratory findings. However, the implications are clear that the methodology is also appropriate in nonpandemic situations and can quickly bring a global mindset to remote corners of the globe and ensure all students experience the “virtual” study abroad, even when there are travel limitations or budget restrictions for students or the institutions.

Practical implications
The implementation detail provided can be easily replicated by other institutions with a global mindset and internationalization goals.

Social implications
The proliferation of COIL-based experiences will impact how study abroad experiences are defined and offered in the future.

Originality/value
While researchers have documented COIL experiences in the academic literature, their use during the COVID-19 pandemic, as often the only solution for on-going internationalization, has not been thoroughly studied or documented. In addition, the class activities further used team-based international workplace pedagogy, authentic engagement and technology.
Cloud-based big data framework towards strengthening disaster risk reduction: systematic mapping
Authors: Mahrin Mohd Naz’ri , Subbarao Anusuyah , Chuprat Suriayati , Abu Bakar Nur Azaliah 
Published: March 2023

Purpose
Cloud computing promises dependable services offered through next-generation data centres based on virtualization technologies for computation, network and storage. Big Data Applications have been made viable by cloud computing technologies due to the tremendous expansion of data. Disaster management is one of the areas where big data applications are rapidly being deployed. This study looks at how big data is being used in conjunction with cloud computing to increase disaster risk reduction (DRR). This paper aims to explore and review the existing framework for big data used in disaster management and to provide an insightful view of how cloud-based big data platform toward DRR is applied.

Design/methodology/approach
A systematic mapping study is conducted to answer four research questions with papers related to Big Data Analytics, cloud computing and disaster management ranging from the year 2013 to 2019. A total of 26 papers were finalised after going through five steps of systematic mapping.

Findings
Findings are based on each research question.

Research limitations/implications
A specific study on big data platforms on the application of disaster management, in general is still limited. The lack of study in this field is opened for further research sources.

Practical implications
In terms of technology, research in DRR leverage on existing big data platform is still lacking. In terms of data, many disaster data are available, but scientists still struggle to learn and listen to the data and take more proactive disaster preparedness.

Originality/value
This study shows that a very famous platform selected by researchers is central processing unit based processing, namely, Apache Hadoop. Apache Spark which uses memory processing requires a big capacity of memory, therefore this is less preferred in the world of research.
Disk diffusion‐based method aids in the detection of vanM‐positive Enterococcus faecium with low vancomycin minimum inhibitory concentrations
Authors: Wang Jue , Li Pei , Xin Lin , Xu Xiaogang , Wang Minggui 
Published: March 2023

AbstractWe first reported the vanM vancomycin resistance gene in enterococci in Shanghai, China in 2006 and later found it to be the predominant van gene in vancomycin‐resistant enterococci (VRE). In this study, we successively collected 1292 Enterococcus faecium and Enterococcus faecalis strains from in‐ and outpatients at Huashan Hospital, Fudan University and found that nearly all of the isolates (1290/1292) were vancomycin‐sensitive determined by the VITEK 2 system. However, using a modified macromethod‐based disk diffusion test, 10 E. faecium isolates that were previously determined to be vancomycin‐sensitive by the VITEK 2 system were found to have colonies in the vancomycin disk inhibition zone. Pulse‐field gel electrophoresis results showed that each randomly selected colony in the inhibition zone belonged to the same clone as the original strain. All 10 isolates were later found to be vanM‐positive. The disk diffusion‐based method may aid in the detection of vanM‐positive E. faecium with low vancomycin minimum inhibitory concentrations and prevent missing the detection of vancomycin sensitivity‐variable enterococci.
COVID‐19 and the fiscal and monetary challenges to implementing Our Common Agenda
Authors: Sowels Nicholas 
Published: March 2023

AbstractThis contribution examines the fiscal and monetary policy legacies of the COVID‐19 pandemic. Thanks to exceptional support from governments and central banks, the world economy returned rapidly to growth following the dramatic global lockdowns of spring 2020. However, the huge fiscal and monetary interventions involved raise significant challenges for future growth and financial stability, especially given the sharp rise in inflation from mid‐2021. These challenges make implementing the ambitious Common Agenda of the United Nations difficult, especially as the war in Ukraine has greatly weakened international cooperation.
Self‐reported alcohol use versus phosphatidylethanol in behavioral trials: A study of people living with HIV in Tshwane, South Africa
Authors: Parry Charles D. H. , Myers Bronwyn , Londani Mukhethwa , Shuper Paul A. , Nkosi Sebenzile , Hahn Judith A. , Kekwaletswe Connie , Morojele Neo K. 
Published: March 2023

AbstractBackgroundAccurately quantifying alcohol use among persons with HIV (PWH) is important for validly assessing the efficacy of alcohol reduction interventions.MethodsWe used data from a randomized controlled trial of an intervention to reduce alcohol use among PWH who were receiving antiretroviral therapy in Tshwane, South Africa. We calculated agreement between self‐reported hazardous alcohol use measured by the Alcohol Use Disorders Identification Test (AUDIT; score ≥8) and AUDIT‐Consumption (AUDIT‐C; score ≥3 for females and ≥4 for males), heavy episodic drinking (HED) in the past 30 days, and heavy drinking in the past 7 days with a gold standard biomarker‐‐phosphatidylethanol (PEth) level (≥50 ng/mL)‐‐among 309 participants. We used multiple logistic regression to assess whether underreporting of hazardous drinking (AUDIT‐C vs. PEth) differed by sex, study arm, and assessment time point.ResultsParticipants' mean age was 40.6 years, 43% were males, and 48% were in the intervention arm. At 6 months, 51% had PEth ≥50 ng/mL, 38% and 76% had scores indicative of hazardous drinking on the AUDIT and AUDIT‐C, respectively, 11% reported past 30‐day HED, and 13% reported past 7‐day heavy drinking. At 6 months, there was low agreement between AUDIT‐C scores and past 7‐day heavy drinking relative to PEth ≥50 (sensitivities of 83% and 20% and negative predictive values of 62% and 51%, respectively). Underreporting of hazardous drinking at 6 months was associated with sex (OR = 3.504. 95% CI: 1.080 to 11.364), with odds of underreporting being greater for females.ConclusionsSteps should be taken to decrease underreporting of alcohol use in clinical trials.
Case series: Voluntary discontinuation of sublingual buprenorphine treatment for opioid use disorder using extended‐release buprenorphine
Authors: Rodriguez Claudia P. , Suzuki Joji 
Published: March 2023

AbstractBackground and ObjectivesDespite its efficacy, patients may still seek to voluntarily discontinue sublingual (SL) buprenorphine treatment, but little guidance exist on how to safely conduct a taper. We, therefore, report on the use of extended‐release buprenorphine (XR‐BUP) to facilitate voluntary treatment discontinuation.MethodsA case series (n = 4).ResultsFour individuals interested in voluntary discontinuation of sublingual buprenorphine treatment were transitioned to varying durations of XR‐BUP, after which all were able to discontinue buprenorphine with minimal withdrawal symptoms. One individual had a brief recurrence to illicit opioid use. All remained engaged in treatment.Discussion and ConclusionsThe use of XR‐BUP, given its long terminal half‐life, may be a helpful option for individuals who are interested in voluntary buprenorphine discontinuation. Collaboration with the patient must include information about the risk of lapse to use and overdose following discontinuation.Scientific SignificanceThe cases reported here provide preliminary support for the use of XR‐BUP to help individuals discontinue buprenorphine treatment. There is only one other case series showing the use of XR‐BUP in helping individuals successfully discontinue buprenorphine treatment. Buprenorphine discontinuation is clinically relevant and there is little guidance in the current literature.
Comparative validation of HAS‐BLED, GARFIELD‐AF and ORBIT bleeding risk scores in Asian people with atrial fibrillation treated with oral anticoagulant: A report from the COOL‐AF registry
Authors: Chichareon Ply , Winijkul Arjbordin , Lip Gregory Y. H. , Krittayaphong Rungroj 
Published: March 2023

AimsComparative data between the HAS‐BLED, GARFIELD‐AF and ORBIT score are limited in anticoagulated Asian patients with atrial fibrillation (AF). We compared the performance of the 3 scores in a nationwide registry.MethodsAF patients treated with oral anticoagulants in the COOL‐AF registry were studied. We fitted the variables of the HAS‐BLED, GARFIELD‐AF and ORBIT score to major bleeding in Cox model. We explored a modified HAS‐BLED by addition of sex and body weight. Discrimination, calibration, net reclassification index (NRI) and decision curve analysis were used to compare the performance of the 3 models.ResultsOf 3402 patients in the registry, 2568 patients who received oral anticoagulant at baseline were studied. Majority of patients (91.1%) received warfarin. The rate of major bleeding was 2.11 per 100 person‐years. The C‐statistics of the GARFIELD‐AF, HAS‐BLED, modified HAS‐BLED and ORBIT score were 0.65 (95% confidence interval [CI] 0.63–0.67), 0.66 (95%CI 0.64–0.68), 0.69 (95%CI 0.67–0.71) and 0.64 (95%CI 0.62–0.66) respectively. There was good agreement between predicted and observed bleeding in the deciles of HAS‐BLED and GARFIELD‐AF scores, while the modified HAS‐BLED score and ORBIT score overestimated the risk in the last decile. The modified HAS‐BLED score had superior NRI than the HAS‐BLED score (26.9%, 95%CI 9.7%–42.2%) and the ORBIT score (31.9%, 95%CI 9.0–53.6%). The NRI between the modified HAS‐BLED and GARFIELD‐AF score was similar. The net benefit curve of the 4 models were overlapping among different thresholds.ConclusionsThe clinical utility for bleeding prediction of GARFIELD‐AF, HAS‐BLED, modified HAS‐BLED and ORBIT scores were similar in anticoagulated Asian patients with AF participating in the COOL‐AF registry. We found no advantage of the ORBIT over HAS‐BLED score for bleeding risk prediction, even in direct oral anticoagulant users.
Trustworthiness as information: Satisfying the understanding condition of valid consent
Authors: Martin Robert K. 
Published: March 2023

AbstractWithin medical ethics, there is widespread agreement that morally valid consent includes an understanding condition. Disagreement centers on what is meant by that understanding condition. Tom Dougherty proposed that this understanding condition should be divided into the two mutually exclusive categories of descriptive information and contextual information. Further, Dougherty argues that each type of information is necessary to satisfy the understanding condition. In contrast, I argue that when the deontic aspect of valid consent is in view, each type of information can be sufficient to satisfy the understanding condition on its own. Moreover, by analyzing delegation, which is conceptually related to consent since both are morally transformative actions, I show that delegation often depends not on descriptive or contextual information but on trust. So, I argue that trustworthiness can also be a type of information that does the same work as descriptive and contextual information in satisfying the understanding condition for valid consent.
The ambiguities of coercion: Mapping adolescents' experiences of coercion in institutional everyday life
Authors: Henriksen Ann-Karina , Øye Christine 
Published: March 2023

AbstractThe article presents a metasynthesis of qualitative studies, which have described and analysed adolescents' experiences of coercion in institutional contexts such as psychiatric care, child welfare and juvenile justice. The study finds that coercion is an ambiguous practice, mainly used for protection and treatment purposes, while it is often experienced as punitive. Acknowledging the ambiguities of coercion can contribute to a more nuanced understanding of practice and experience, which is useful for reducing the harmful effects of coercion and strengthening participatory methods of care and treatment.
Increasing circulating levels of Tenascin C in response to the Wingate anaerobic test
Authors: Ekström Ola , Ström Kristoffer , Mir Bilal Ahmad , Laurila Esa , Wessman Ylva , Lehtovirta Mikko , Eriksson Karl‐Fredrik , Hansson Ola 
Published: March 2023

AbstractAimTenascin C (TNC) is a large extracellular matrix glycoprotein. It is involved in development and upregulated both during tissue repair and in several pathological conditions, including cardiovascular disease. Extracellular matrix proteins play a role in promoting exercise responses, leading to adaptation, regeneration, and repair. The main goal of this study was to investigate whether a short anaerobic effort leads to increased levels of TNC in serum.MethodsThirty‐nine healthy men performed a Wingate test followed by a muscle biopsy. Myoblasts were isolated from the muscle biopsies and differentiated to myotubes ex vivo. TNC RNA was quantified in the biopsies, myotubes and myoblasts using RNA sequencing. Blood samples were drawn before and 5 min after the Wingate test. Serum TNC levels were measured using enzyme‐linked immunosorbent assay.ResultsAfter the Wingate test, serum TNC increased on average by 23% [15–33], median [interquartile range]; PWilcoxon < 0.0001. This increase is correlated with peak power output and power drop, but not with VO2max. TNC RNA expression is higher in myoblasts and myotubes compared to skeletal muscle tissue.ConclusionTNC is secreted systemically as a response to the Wingate anaerobic test in healthy males. The response was positively correlated with peak power and power drop, but not with VO2max which implicates a relation to mechanical strain and/or blood flow. With higher expression in undifferentiated myoblast cells than muscle tissue, it is likely that TNC plays a role in muscle tissue remodelling in humans. Our findings open for research on how TNC contributes to exercise adaptation.
Lactate and ammonia measurements during cardiopulmonary exercise testing and its recovery phase—Consideration of age and sex in its interpretation
Authors: Ratia Nadja , Lantto Hanna , Rotgers Emmi , Kouri Vesa‐Petteri , Auranen Mari , Luukkonen Ritva , Piirilä Päivi 
Published: March 2023

AbstractBackgroundCardiopulmonary exercise testing with lactate and ammonia samples is used in the diagnostics of metabolic myopathies. As the effect of age and sex on the exercise lactate and ammonia levels are incompletely characterized for clinical associations, our aim was to assess the effects of these factors on healthy subjects to improve the test's interpretation.MethodsSeventy‐three subjects (34 men and 39 women; age < 35 years, n = 26, 35–50 years, n = 23 and >50 years, n = 24) performed cardiopulmonary exercise tests with venous blood gases, plasma lactate and ammonia analyses at rest, during exercise, and 2, 4, 6, 10, 20 and 30 min into recovery.ResultsThe lactate (p = 0.021–0.044) and ammonia values (p = 0.002–0.038) differed between men and women measured during recovery and between three age groups point‐by‐point in maximal exercise and the recovery phase and also longitudinally, most notably between <35‐ and >50‐year‐groups (lactate p = <0.001–0.040, ammonia p = 0.002–0.03). In the linear model, the yearly reduction of lactate was maximally −0.119 mmol/L and that of ammonia −1.514 µmol/L. The yearly reduction of lactate was greater in women than in men (−0.131 vs.−0.099 2 min into recovery), but for ammonia, the results were not as clear.ConclusionsPlasma lactate and ammonia concentrations measured during cardiopulmonary exercise were lower in older age groups, and their yearly reduction was also influenced by sex. These data give new information on lactate and ammonia levels and the effect of aging on them during exercise and recovery and may help assess cardiopulmonary exercise testing results.
Infection‐related mortality after HLA‐identical and haploidentical hematopoietic cell transplantation using reduced‐intensity conditioning in an outpatient setting
Authors: Jaime‐Pérez José Carlos , Meléndez‐Flores Jesús D. , Ramos‐Dávila Eugenia M. , Gutiérrez‐Aguirre César Homero , Cantú‐Rodríguez Olga G. , Marfil‐Rivera Luis Javier , Áncer‐Rodríguez Jesús , Gómez‐Almaguer David 
Published: March 2023

AbstractBackgroundDespite the improvements in supportive care for allogeneic‐hematopoietic cell transplantation (allo‐HCT) recipients, infectious complications and infection‐related mortality (IRM) continue to be a major issue for transplantation centers.MethodsWe herein report the infectious complications and IRM of 107 and 89 patients that underwent haploidentical (haplo‐HCT) or HLA‐identical HCT at a tertiary referral center during 2013‐2020. Patients in the haplo‐HCT group received post‐transplant cyclophosphamide (PT‐Cy), and all received reduced‐intensity conditioning regimens.ResultsMore haplo‐HCT recipients presented severe infections in the pre‐engraftment period (22.4% vs. 6.7%, p = 0.003). Viral (14.9% vs. 4.5%, p = 0.016) and fungal (12.1% vs. 1.1%, p = 0.003) etiologies were more common in this period in this group. The 100‐day and 2‐year cumulative incidence of IRM was 15% and 21% for the haplo‐HCT and 5.6% and 17% for the HLA‐identical group; no significant differences were observed between the groups. Fungal pathogens mainly contributed to IRM (33.3%). Infections were the most common cause of mortality (40/81, 49.4%). There were significant differences in donor/recipient CMV serostatus between transplant groups (0.002).ConclusionsNo differences in IRM were observed based on allo‐HCT type, with more haplo‐HCT patients suffering from severe infections in the pre‐engraftment period. Studies to assess future prevention, diagnostic, and treatment strategies to reduce IRM are warranted.