bluuebunny/crossref_metadata_2025_split huggingface dataset:
Attachment style and post-bariatric surgery health behaviours: the mediating role of self-esteem and health self-efficacy
Authors: Pyykkö Johanna Eveliina , Hinnen Chris , Aydin Ömrüm , Nieuwdorp Max , De Brauw L. Maurits , Bruin Sjoerd C. , van Olst Nienke , Gerdes Victor E. A. , Sanderman Robbert , Hagedoorn Mariët 
Published: August 2023

Abstract
Background
Attachment avoidance and anxiety have been linked to overweight and poor health behaviours, yet the mechanisms that underpin the relationship between attachment and health behaviours are not fully understood. Self-esteem and self-efficacy have been found to differ between attachment styles, rendering these variables potential mediators of the relationship. This longitudinal study investigated the serial mediation between preoperative attachment and 2-year post-operative health behaviours through self-esteem and health self-efficacy.

Methods
Participants were 263 bariatric surgery patients (75.7% females, aged 47.7 ± 10.4 years, BMI 38.9 ± 3.6 kg/m2) assessed before the operation and again one and two years after the surgery. Patients completed the Experiences for Close Relationships Brief Scale, Rosenberg Self-esteem scale, Weight Efficacy Lifestyle Questionnaire, Bariatric Surgery Self-Management Questionnaire, Exercise Self-Efficacy Scale and the Exercise Behaviour Scale.

Results
Higher preoperative attachment anxiety and avoidance were associated with lower self-esteem one year after bariatric surgery and poorer health self-efficacy two years after the surgery. Self-esteem and health self-efficacy mediated the relationships between preoperative anxious and avoidant attachment and 2- year post-operative diet adherence and physical activity.

Conclusions
Helping patients to feel more worthy and reinforcing their beliefs about their own competences could lead to higher engagement with healthy lifestyle and adherence to treatment protocols, ultimately helping patients to achieve their goals for bariatric surgery.

Clinical trial registration
BARIA: Netherlands Trial Register: NL5837 (NTR5992) https://www.trialregister.nl/trial/5837. Diabaria: ClinicalTrials.gov identifier (NCT number): NCT03330756.
L-DOPA induces iron accumulation in roots of Ipomoea aquatica and Arabidopsis thaliana in a pH-dependent manner
Authors: Hsieh En-Jung , Liao Siao-Wei , Chang Ching-Yuan , Tseng Chu-Han , Wang Shan-Li , Grillet Louis 
Published: August 2023

Abstract
Background
Iron deficiency is the leading cause of anemia worldwide, particularly in countries with predominant plant-based diets. Plants constitute the main source of dietary iron. Increasing their iron concentration could reduce the occurrence of anemia. The water spinach Ipomoea aquatica is consumed as a vegetable throughout Asia and tolerates high iron concentrations making it an attractive candidate for iron biofortification. L-DOPA is an allelopathic molecule secreted by some legumes. L-DOPA can trigger the expression of Fe deficiency-inducible genes, and could potentially be used as a biostimulant to increase Fe concentration.

Results
L-DOPA significantly affected root growth of water spinach, and triggered a massive accumulation of Fe in roots. Both effects were exacerbated when L-DOPA was dissolved in KOH, which is surprising given that L-DOPA is less stable at high pH. To check whether a higher pH could indeed increase the bioactivity of L-DOPA, we used Arabidopsis thaliana, which grows at lower pH than water spinach, and subjected the plants to L-DOPA treatments at pH 5.5 and pH 6.0, which are both within the optimal range for Arabidopsis nutrition. At pH 6.0, the root growth of Arabidopsis was more strongly inhibited than at pH 5.5. We found that at higher pH, L-DOPA oxidizes to form a melanin precipitate.

Conclusions
We concluded that the oxidation of L-DOPA that we observed upon solubilization in KOH, or in nutrient solutions at slightly higher pH produces melanin-related molecules that are more potent than L-DOPA itself to trigger the primary root growth inhibition, Fe uptake and root Fe accumulation in water spinach and Arabidopsis.
Tidal asymmetry and transition in the Singapore Strait revealed by GNSS interferometric reflectometry
Authors: Peng Dongju , Soon Kit Ying , Khoo Victor H. S. , Mulder Evert , Wong Poh Weng , Hill Emma M. 
Published: August 2023

AbstractThe Singapore Strait is located at the transition between the dominantly semidiurnal Indian Ocean and the mixed-to-diurnal South China Sea, resulting in complex tidal dynamics. In this work, we use sea-level estimates from two coastal Global Navigation Satellite Systems (GNSS) stations and one tide gauge to study tides and tidal asymmetry in the Strait. We first generate sea-level measurements from GNSS signal-to-noise ratio (SNR) data using the GNSS Interferometric Reflectometry technique, which can estimate sea-surface heights from a coastal GNSS station. Second, we perform tidal harmonic analysis and quantify tidal asymmetry based on the skewness method. Finally, we examine seasonal sea-level changes in the Strait from GNSS SNR data, tide-gauge records and satellite altimetry. Our results reveal an increase in M2 and S2 amplitudes toward the west of the Strait and a decrease in the K1 and O1 amplitudes. Our results also show that tides at the two sites in the east are ebb dominant with asymmetry originating from the O1–K1–M2 triad by astronomical forcing, whereas tidal asymmetry at the site in the west is flood dominant and mainly caused by non-linear interaction of the major tidal constituents. Analysis of seasonal sea-level changes shows that annual amplitudes in the east are around 13.6 cm, and 6.7 cm in the west. A possible explanation for the discrepancy in the amplitudes is the effect of seasonal monsoon winds flowing from the South China Sea.
Lattice modulation strategies for 2D material assisted epitaxial growth
Authors: Chen Qi , Yang Kailai , Liang Meng , Kang Junjie , Yi Xiaoyan , Wang Junxi , Li Jinmin , Liu Zhiqiang 
Published: August 2023

AbstractAs an emerging single crystals growth technique, the 2D-material-assisted epitaxy shows excellent advantages in flexible and transferable structure fabrication, dissimilar materials integration, and matter assembly, which offers opportunities for novel optoelectronics and electronics development and opens a pathway for the next-generation integrated system fabrication. Studying and understanding the lattice modulation mechanism in 2D-material-assisted epitaxy could greatly benefit its practical application and further development. In this review, we overview the tremendous experimental and theoretical findings in varied 2D-material-assisted epitaxy. The lattice guidance mechanism and corresponding epitaxial relationship construction strategy in remote epitaxy, van der Waals epitaxy, and quasi van der Waals epitaxy are discussed, respectively. Besides, the possible application scenarios and future development directions of 2D-material-assisted epitaxy are also given. We believe the discussions and perspectives exhibited here could help to provide insight into the essence of the 2D-material-assisted epitaxy and motivate novel structure design and offer solutions to heterogeneous integration via the 2D-material-assisted epitaxy method.
Graphical Abstract
Evaluating the effect of prebiotics on the gut microbiome profile and β cell function in youth with newly diagnosed type 1 diabetes: protocol of a pilot randomized controlled trial
Authors: Ismail Heba M. , Spall Maria , Evans-Molina Carmella , DiMeglio Linda A. 
Published: August 2023

Abstract
Introduction
Data show that disturbances in the gut microbiota play a role in glucose homeostasis, type 1 diabetes (T1D) risk and progression. The prebiotic high amylose maize starch (HAMS) alters the gut microbiome profile and metabolites favorably with an increase in bacteria producing short chain fatty acids (SCFAs) that have significant anti-inflammatory effects. HAMS also improves glycemia, insulin sensitivity, and secretion in healthy non-diabetic adults. Additionally, a recent study testing an acetylated and butyrylated form of HAMS (HAMS-AB) that further increases SCFA production prevented T1D in a rodent model without adverse safety effects. The overall objective of this human study will be to assess how daily HAMS-AB consumption impacts the gut microbiome profile, SCFA production, β cell heath, function, and glycemia as well as immune responses in newly diagnosed T1D youth.

Methods and analysis
We hypothesize that HAMS-AB intake will improve the gut microbiome profile, increase SCFA production, improve β cell health, function and glycemia as well as modulate the immune system. We describe here a pilot, randomized crossover trial of HAMS-AB in 12 newly diagnosed T1D youth, ages 11–17 years old, with residual β cell function. In Aim 1, we will determine the effect of HAMS-AB on the gut microbiome profile and SCFA production; in Aim 2, we will determine the effect of HAMS-AB on β cell health, function and glycemia; and in Aim 3, we will determine the peripheral blood effect of HAMS-AB on frequency, phenotype and function of specific T cell markers. Results will be used to determine the effect-size estimate of using HAMS-AB. We anticipate beneficial effects from a simple, inexpensive, and safe dietary approach.

Ethics and dissemination
The Institutional Review Board at Indiana University approved the study protocol. The findings of this trial will be submitted to a peer-reviewed pediatric journal. Abstracts will be submitted to relevant national and international conferences.

Trial registration
NCT04114357; Pre-results.
Using the RE-AIM framework to evaluate the implementation and effectiveness of a WHO HEARTS-based intervention to integrate the management of hypertension into HIV care in Uganda: a process evaluation
Authors: Muddu Martin , Semitala Fred Collins , Kimera Isaac Derick , Musimbaggo Douglas Joseph , Mbuliro Mary , Ssennyonjo Rebecca , Kigozi Simon Peter , Katwesigye Rodgers , Ayebare Florence , Namugenyi Christabellah , Mugabe Frank , Mutungi Gerald , Longenecker Chris T. , Katahoire Anne R. , Schwartz Jeremy I. , Ssinabulya Isaac 
Published: August 2023

Abstract
Background
World Health Organization (WHO) HEARTS packages are increasingly used to control hypertension. However, their feasibility in persons living with HIV (PLHIV) is unknown. We studied the effectiveness and implementation of a WHO HEARTS intervention to integrate the management of hypertension into HIV care.

Methods
This was a mixed methods study at Uganda’s largest HIV clinic. Components of the adapted WHO HEARTS intervention were lifestyle counseling, free hypertension medications, hypertension treatment protocol, task shifting, and monitoring tools. We determined the effectiveness of the intervention among PLHIV by comparing hypertension and HIV outcomes at baseline and 21 months. The RE-AIM framework was used to evaluate the implementation outcomes of the intervention at 21 months. We conducted four focus group discussions with PLHIV (n = 42), in-depth interviews with PLHIV (n = 9), healthcare providers (n = 15), and Ministry of Health (MoH) policymakers (n = 2).

Results
Reach: Among the 15,953 adult PLHIV in the clinic, of whom 3892 (24%) had been diagnosed with hypertension, 1133(29%) initiated integrated hypertension-HIV treatment compared to 39 (1%) at baseline. Among the enrolled patients, the mean age was 51.5 ± 9.7 years and 679 (62.6%) were female. Effectiveness: Among the treated patients, hypertension control improved from 9 to 72% (p < 0.001), mean systolic blood pressure (BP) from 153.2 ± 21.4 to 129.2 ± 15.2 mmHg (p < 0.001), and mean diastolic BP from 98.5 ± 13.5 to 85.1 ± 9.7 mmHg (p < 0.001). Overall, 1087 (95.9%) of patients were retained by month 21. HIV viral suppression remained high, 99.3 to 99.5% (p = 0.694). Patients who received integrated hypertension-HIV care felt healthy and saved more money. Adoption: All 48 (100%) healthcare providers in the clinic were trained and adopted the intervention. Training healthcare providers on WHO HEARTS, task shifting, and synchronizing clinic appointments for hypertension and HIV promoted adoption. Implementation: WHO HEARTS intervention was feasible and implemented with fidelity. Maintenance: Leveraging HIV program resources and adopting WHO HEARTS protocols into national guidelines will promote sustainability.

Conclusions
The WHO HEARTS intervention promoted the integration of hypertension management into HIV care in the real-world setting. It was acceptable, feasible, and effective in controlling hypertension and maintaining optimal viral suppression among PLHIV. Integrating this intervention into national guidelines will promote sustainability.
Heritage impact assessment of Adi Ganga Kalighat, Kolkata, India, towards SDG 11.4 and 8.9 for urban heritage
Authors: Chakraborty Shilpi , Ji Shiva 
Published: August 2023

AbstractThis study addresses the complex issue of preserving the historic fabric and cultural assets while promoting sustainable development in urban areas, focusing on the Adi Ganga River in Kolkata, India. The problem arises due to the encroachment and poor maintenance of historical sites. The research questions aim to assess the protection of Adi Ganga River's historic fabric and enhance heritage preservation in line with UN SDGs 11.4 and 8.9, emphasizing cultural conservation and sustainable tourism supporting regional heritage and livelihoods. The study utilizes Heritage Impact Assessment (HIA) to evaluate the protection of Adi Ganga River’s historic fabric and enhance heritage preservation in line with sustainable development goals. It provides an impact assessment matrix for mitigating the adverse impact of development projects on cultural heritage sites and reveals 25 critical development indicators. HIA is an effective tool for preserving cultural heritage assets and achieving sustainable development goals. Incorporating HIA into the Environmental Impact Assessment structure can create an organized and transparent process for assessing the ecological implications of development projects on cultural heritage sites. The findings emphasize the significance of sustainable HIA for preserving tangible/intangible heritage, promoting tourism and employment, and balancing sustainability and culture in sustainable development. This research holds significance as it emphasizes the importance of cultural heritage in fostering sustainable development and aligning with UN SDGs. Policymakers should consider incorporating sustainable HIA in decision-making to balance sustainability and culture.
Reevaluating First-line Therapies in Youth-Onset Type 2 Diabetes
Authors: Chung Stephanie T , Davis Faith , Patel Tejal , Mabundo Lilian , Estrada Doris E 
Published: August 2023

Abstract
The prevalence of youth-onset type 2 diabetes is growing worldwide and current first-line treatment with metformin and intensive behavior and lifestyle changes are suboptimal in over 50% of youth within 2 years of diagnosis. This perspective article is a call to action for reevaluation of existing strategies and critical appraisal of metformin as first-line therapy in youth-onset type 2 diabetes. Increased attention should be given to novel therapeutics approved in youth, including glucagon-like 1 receptor agonists, sodium glucose cotransporter-2, and sociocultural interventions that will promote diabetes self-management.
Effect of Pregnancy and Menopause on Micropapillary Thyroid Carcinomas During Active Surveillance
Authors: Ghirri Arianna , Campopiano Maria Cristina , Prete Alessandro , Matrone Antonio , Gambale Carla , Piaggi Paolo , Rago Teresa , Scutari Maria , Elisei Rossella , Molinaro Eleonora 
Published: August 2023

Abstract

Background
The effect of estrogen and beta-human chorionic gonadotropin on micropapillary thyroid carcinoma (mPTC) is not defined. Pregnancy and menopause could represent critical moments during active surveillance (AS) for women with mPTC.

Objective
To evaluate the effect of either pregnancy or menopause on growth of mPTCs on AS.

Patients and Methods
Women with mPTC on AS who became pregnant or underwent menopause during AS were evaluated in this retrospective observational study. The primary outcome was disease progression according to the AS protocol. The secondary outcome was the shrinkage of mPTCs. We compared the menopause group of patients with 2 unmatched control groups: (1) the pre-menopause group of patients on AS who had not experienced menopause yet and (2) the post-menopause group of patients who started AS while already in menopause.

Results
Five patients who became pregnant and 9 who underwent menopause during AS were enrolled. No patient from either group had a disease progression, and all pregnant patients showed stable disease after pregnancy. Four patients of the menopause group (44%) experienced mPTC shrinkage. The percentage of patients with mPTC shrinkage was significantly higher in the menopause group than in the 2 control groups.

Conclusions
mPTC AS appears to be safe and feasible in patients who become pregnant or undergo menopause during surveillance. Our data suggest a possible association between menopause and mPTC shrinkage during AS.
Designing Strategy for High Refractive Index Polymers: From the Molecular Level to Bulk Structure Control
Authors: Watanabe Seigo , Oyaizu Kenichi 
Published: August 2023

Abstract
High refractive index polymers (HRIPs) are essential materials for many optical applications, including organic light-emitting diodes (OLEDs), charge-coupled devices (CCDs), complementary metal oxide semiconductors (CMOS), eyeglasses, and optical waveguides. Various molecular designs, synthetic routes, and material preparation methods have been reported to increase the refractive index (RI) of polymers; however, increasing the RI using only organic (and classical) components is difficult. Other properties, such as low or high Abbe numbers (RI dispersion), low birefringence, and high transparency, are also required for HRIPs depending on the intended wavelength usage, which ranges from visible to infrared (IR) light and X-ray applications. This review summarizes the recent developments in HRIPs, including their synthesis, properties, and applications, and provides future prospects for achieving HRIPs with the desired performances.
Implementation Fidelity of a Cybercycling Curriculum among Children with Behavioral Health Disorders
Authors: Bowling April B. , Slavet James D. , Garcia Jeanette M. , Wood Brian J. , Miller Daniel P. , Hermesch Robert M. , Kow Richard Z. , Newlan Sami A. , Davison Kirsten K. 
Published: August 2023

ABSTRACT
Despite the physical, cognitive, and psychological health benefits associated with moderate to vigorous physical activity (MVPA), children with behavioral health disorders such as attention deficit/hyperactivity disorder, autism, and oppositional defiant disorder tend to display very low levels of MVPA. Given that community physical activity programs generally do not cater to children with behavioral health disorders, special education and therapeutic school settings are particularly important environments in which to test MVPA programs in this underserved population. Manville Moves is a 7-wk cybercycling intervention designed specifically for children with behavioral health disorders, including social, emotional, and behavioral disabilities. The program was integrated into school physical education (PE) programming in a therapeutic day school and evaluated over one school year. Guided by Carroll et al.'s framework of implementation fidelity, this mixed methods study documents the implementation fidelity of, including student engagement in, Manville Moves. Manville Moves was implemented with high fidelity and engaged all enrolled children (N = 103). Nearly 90% of sessions were implemented as planned. Students met almost all riding intensity and duration targets; participants averaged 100.5 min of riding and 76% of maximum HR over the course of the intervention. Staff reported low levels of burden, and student refusals were extremely rare. In addition, most students demonstrated high levels of engagement, with the awards, prizes, and video gaming mode all identified as critical motivators. In conclusion, beyond demonstrating that a cybercycling PE curriculum is feasible and can engage students with behavioral health challenges, this study identified several lessons learned that could benefit future implementations of the program.
The Impact of Fitness on Surgical Outcomes: The Case for Prehabilitation
Authors: Myers Jonathan N. , Fonda Holly 
Published: August 2023

ABSTRACTIn recent years, a growing body of research has demonstrated that an individual’s fitness level is a strong and independent marker of risk for cardiovascular and all-cause mortality. In addition, modest improvements in fitness through exercise intervention have been associated with considerable health outcome benefits. These studies have generally assessed fitness as a baseline marker in traditional epidemiological cohorts. However, there has been a recent recognition that fitness powerfully predicts outcomes associated with a wide range of surgical interventions. The concept of "prehabilitation" is based on the principle that patients with higher functional capability will better tolerate a surgical intervention, and studies have shown that patients with higher fitness have reduced postoperative complications and demonstrate better functional, psychosocial, and surgery-related outcomes. This review focuses on the impact of fitness on surgical outcomes and provides a rationale in support of routine application of prehabilitation in the management of patients undergoing surgery.
From a Vital Sign to Vitality: Selling Exercise So Patients Want to Buy It
Authors: Segar Michelle L. , Guérin Eva , Phillips Edward , Fortier Michelle 
Published: August 2023

ABSTRACT
Exercise is Medicine® (EIM) and physical activity as a vital sign are based on health-focused research and reflect ideal frames and messages for clinicians. However, they are nonoptimal for patients because they do not address what drives patients’ decision-making and motivation. With the growing national emphasis on patient-centered and value-based care, it is the perfect time for EIM to evolve and advance a second-level consumer-oriented exercise prescription and communication strategy. Through research on decision-making, motivation, consumer behavior, and meaningful goal pursuit, this article features six evidence-based issues to help clinicians make physical activity more relevant and compelling for patients to sustain in ways that concurrently support patient-centered care. Physical activity prescriptions and counseling can evolve to reflect affective and behavioral science and sell exercise so patients want to buy it.