bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long-term survival of patients with cerebrovascular accident, depending on sex and age: data from the REGION-M registry
Authors: Tolpygina S. N. , Zagrebelny A. V. , Chernysheva M. I. , Kutishenko N. P. , Voronina V. P. , Dmitrieva N. A. , Lerman O. V. , Lukina Yu. V. , Lukyanov M. M. , Okshina E. Yu. , Parsadanyan N. E. , Martsevich S. Yu. , Drapkina O. M. 
Published: September 2023

Aim. To study the long-term survival of patients with cerebrovascular accident, depending on sex and age.Material and methods. The outpatient part of the REGION-M registry (patients with cerebrovascular accident, hospitalized in a Moscow hospital) included 684 patients assigned to the City Polyclinic № 64 (Moscow), discharged from the F. I. Inozemtsev City Clinical Hospital (Moscow) in the period from January 1, 2012 to April 30, 2017 with a diagnosis of stroke, which were divided into 5 age groups: group 1 — ≤50 years, n=72 (10,5%), group 2 — 51-60 years old, n=122 (17,8%), group 3 — 61-70 years old, n=156 (22,8%), group 4 — 71-80 years old, n=185 (27,0%) and group 5 — ≥81 years old, n=149 (21,8%). The survival of patients was assessed at the 2nd and 3rd stages after 4,2 (2,4-5,6) and 5,5 (2,4-7,0) years.Results. The mortality of patients in the long-term follow-up period significantly increased with age. There were following mortality rate for stages 2 and 3 stages: 18-50 years old — 8,3 and 22,2%, 51-60 years old — 18 and 36,9%, 61-70 years old — 41 and 56,4%, 71-80 years old — 54,1 and 73%, >81 years — 76,5 and 87,9% (p<0,0001 for all groups). At stages 2 and 3, mortality among men was higher than among women in groups 2-4, below in group 1 and did not differ in the oldest age group. In multivariate analysis, the following factors had prognostic significance: age — hazard ratio (HR) of death, 1,035 (95% confidence interval (CI): 1,029-1,041, p=0,001), sex — HR, 0,720 (95% CI: 0,43-0,123, p=0,001) and disability before stroke — HR, 0,999 (95% CI: 0,998-1,000, p=0,002).Conclusion. In long-term follow-up, the mortality of patients with cerebrovascular accident was significantly higher in older age groups, as well as among men.
Photoplethysmography factors associated with undiagnosed hypertension in men with low and moderate cardiovascular risk
Authors: Korolev A. I. , Fedorovich A. A. , Gorshkov A. Yu. , Chashchin M. G. , Dadaeva V. A. , Mikhailova M. A. , Omelyanenko K. V. , Strelkova A. V. , Drapkina O. M. 
Published: September 2023

Aim. To study the functional state of the terminal arteries and arterioles of the skin using photoplethysmography (PPG) in men with hypertension (HTN) of low and moderate cardiovascular risk (CVR) and to identify morphofunctional diagnostic criteria associated with HTN.Material and methods. A total of 118 healthy men (30-60 years old) underwent clinical and biochemical blood tests, PPG, ultrasound of cardiac and main arteries, 24-hour blood pressure monitoring. According to 24-hour blood pressure monitoring, two groups were formed: the control group — 59 normotensive men, HTN group — 59 men with HTN.Results. According to the PPG data, men with HN had higher normalized augmentation index (Alp75) (3,8 and -5,25%; (p<0,005)), stiffness index (SI) (7,6 and 7,35 m/s) (p<0,05) and reflection index (RI) (36,5 and 28,4%) (p<0,005), respectively. According to multivariate analysis, an increase in RI ≥30,6% (odds ratio, 4,6; p=0,0476) and SI ≥7,9 m/s (odds ratio, 3,69; p=0,019) was significantly associated with HTN. A regression model has been developed that includes age ≥35 years, RI ≥30,6% and SI ≥7,9 m/s, which allows predicting HTN in men with low and moderate cardiovascular risk with a sensitivity of 78% and a specificity of 62,1%.Conclusion. Men with HTN of low and moderate CVR are characterized by an increase in vascular stiffness, tone of smooth muscle cells, terminal muscular arteries and arterioles, and an increase in pulse wave velocity. The developed model can be used to predict hypertension in these patients and determine indications for further examination.
Dashboard to analyze associations of socio-economic and environmental inequality of regions with health indicators. Guidelines
Authors: Zelenina A. A. , Shalnova S. A. , Maksimov S. A. 
Published: September 2023

The guidelines describe a dashboard designed to monitor and analyze associations of socio-economic and environmental inequality of regions with health indicators.The guidelines are addressed to managers and employees of health authorities, managers and employees of medical prevention centers, primary care physicians, and also as a teaching material for students of higher medical education institutions, residents and graduate students.
Melangkah Menuju Kesehatan Mental yang Optimal: Program Inovatif di Lembaga Pendidikan Islam
Authors: Rofiqi Rofiqi , Iksan  , M. Mansyur  
Published: September 2023

Pendidikan kesehatan mental merupakan aspek yang penting bagi siswa di sekolah, namun seringkali terabaikan oleh lembaga pendidikan. Padahal siswa seringkali menghadapi tekanan akademik yang tinggi, tuntutan sosial, serta tantangan emosional yang dapat berdampak negatif pada kesejahteraan mental mereka yang sekaligus juga mempengaruhi prestasi akademik. Kajian ini bertujuan untuk memberikan alternatif solusi tentang inovasi pendidikan yang bisa dilakukan dalam mengembangkan progran pendidikan kesehatan mental di lembaga pendidikan. Metode penelitian dilakukan melalui Systemetical Literature Review (SLR) dengan menggunakan aplikasi Publish or Perish sebagai intrumen identikasi artikel-artikel jurnal. Artikel yang diperoleh dan dielimenasi berdasarkan kriteria kualitas, kebaharuan, dan kesesuaian dengan tema penelitian secara spesifik. Hasil peneltian ini menunjukkan bahwa pendidikan kesehatan mental memiliki peran yang signifikan dalam kesejahteraan mental siswa di sekolah. Oleh karena itu, inovasi pendidikan kesehatan mental harus dilakukan dalam konteks pengembangan progam sekolah. Inovasi pendidikan kesehatan mental yang dapat dilakukan meliputi kolaborasi antara lembaga pendidikan Islam dengan tenaga profesional, dan integrasi kurikulum pendidikan kesehatan dengan kurikulum sekolah.
Developing One Health capacity and networks through virtual training
Authors: Arevalo Maria de la Puente , Maud Jenny , Alviti Alessandra , Tang Hao , George Acty , Simmons Heather , Castellan David , Siriaroonrat Boripat , Neill Eimear O , Longchar Achila , Nova Rodrigo J. , Chikurunhe Wilmot , Obonyo Mark , Newman Scott , Dhingra Madhur , Sumption Keith 
Published: September 2023

The Food and Agriculture Organization of the United Nations (FAO) Virtual Learning Centers (VLCs) deliver online tutored courses with the aim of developing field capacity to integrate wildlife and ecosystem elements to approach One Health challenges. These courses also aim to create networks of professionals under the One Health umbrella.
These courses cater to professionals from a variety of organizations and with a wide range of expertise, including animal health, public health, wildlife and natural resource management. The courses combine self-directed interactive modules with virtual workshops focusing on problem-based learning case studies (PBLs). Additionally, participants are encouraged to participate in an online asynchronous discussion forum.
Each course is delivered for multiple countries within a FAO region and is tailored to cover specific One Health topic areas. Once the topic area is defined, subject matter experts and the regional VLC build the training activities by developing course-specific PBLs and selecting up to five self-directed modules that introduce concepts related to those PBLs from the course catalog of training materials. The development of the training materials and the delivery of each course involves a multidisciplinary team of professionals from different countries and backgrounds.
The course was piloted for the Pacific Islands in 2021 and then run for other regions such as Southern Africa and Eastern Africa. In the future, this training activity could also be delivered in a blended format, combining virtual learning with face-to-face workshops.
CREATINA E SEUS BENEFÍCIOS PARA HIPERTROFIA MUSCULAR - UMA REVISÃO SISTEMÁTICA DA LITERATURA
Authors: Guimarães Moreira Dilenya , Miranda Luciano Thiago Alessandro 
Published: September 2023

INTRODUÇÃO: A creatina é um aminoácido encontrado naturalmente no organismo, principalmente nos músculos esqueléticos. Ela desempenha um papel fundamental na geração de energia, pois está envolvida na produção de adenosina trifosfato (ATP), a molécula responsável por fornecer energia para as células do corpo. METODOLOGIA: Esse estudo de revisão da literatura foi desenvolvido por busca de artigos indexados, estudos longitudinais, transversais e ensaios clínicos, no qual foram encontrados 200 artigos no período de 2001 a 2022. RESULTADOS: foram encontrados um total de 200 artigos sendo 80 da base de dados PubMed MEDLINE, 60 SciELO, 40 CDSR e 20 BVS sendo que um total de 8 estudos foram selecionados para a revisão sistemática. CONCLUSÃO: creatina é um suplemento que, quando ingerido de forma adequada, tem um efeito muito benéfico para o ganho de massa muscular
Palavras-chave: Creatina; Hipertrofia; Ganho Muscular.
DISTRIBUÇÃO ESPACIAL E TENDÊNCIA TEMPORAL DA NEOPLASIA DE PROSTATA NO BRASIL E REGIÕES ENTRE 2008 A 2022.
Authors: Aires Oliveira Campos Guilherme , Pastor da Silva Paiva Nicole , Soares Martins Gustavo , Rassy Carneiro Saul 
Published: September 2023

INTRODUÇÃO: A Neoplasia Maligna de Próstata é uma patologia que vem crescendo de forma exponencial mundialmente, nos últimos 10 anos foram notificados cerca de 20% a mais de casos novos6, e por este motivo representa um importante fator de diminuição da saúde da em nível global. No Brasil, ele é o segundo câncer mais prevalente entre a população masculina e também tem se revelado com uma incidência crescente. OBJETIVOS: analisar o perfil epidemiológico dos casos de neoplasia maligna de próstata no Brasil no período de 2008 a 2022 bem como a taxa de mortalidade do país e de suas regiões METODOLOGIA: Trata-se de um estudo epidemiológico analítico retrospectivo realizado por meio da coleta de dados anuais referentes ao período entre 2008 até 2022, no Brasil, disponibilizado pelo Sistema de Informações Hospitalares (SIH) e Datasus RESULTADOS: Nos 15 anos de análise foram notificadas 413.437 internações e 37.659 óbitos por CP. O País registrou uma taxa média de mortalidade 1,23 óbitos por 100 mil habitantes, sendo que a da região Sul, foi a maior taxa média registrada dentre as regiões do país, cerca de 1,52 óbitos por 100 mil habitantes. Quanto aos desfechos dos casos, a taxa média de letalidade do CP no Brasil foi de 8,99%, onde a região Norte foi a que se destacou com o maior número de desfechos negativos com um índice de 13,1%. CONCLUSÃO: As taxas de incidência, mortalidade e letalidade da neoplasia maligna de próstata no Brasil, e suas regiões Norte, Nordeste, Sul, sudeste e Centro-oeste apresentaram um crescimento ao longo dos anos de 2008 a 2022.
Palavras chave: Urologia; Próstata; Neoplasia; Câncer; Epidemiologia
EPIDEMIOLOGIA DAS INTERNAÇÕES POR FRATURA DE FÊMUR NO TOCANTINS DE 2018 A 2022
Authors: Paiva Rodrigues da Cunha Mateus , Pacheco David Walter , Rosa Golart Luiz Guilherme , Borges de Moraes João Paulo 
Published: September 2023

Introdução: A fratura do fêmur (FM) acontece quando surge uma fratura no osso da coxa, que é o maior (comprimento) e mais resistente osso do corpo humano. Os sinais e sintomas de uma fratura de fêmur incluem, em geral, dor intensa na região da fratura e Incapacidade de mover a perna afetada. O diagnóstico de uma fratura de fêmur é feito por meio de um exame físico, histórico clínico do paciente e, geralmente, confirmação por meio de exames de imagem, como radiografias ou tomografia computadorizada O tratamento de uma fratura de fêmur depende do tipo e gravidade da fratura. METODOLOGIA: Estudo epidemiológico de natureza descritiva, realizado por meio da coleta de dados anuais das fraturas de fêmur disponibilizado pelo Sistema de Internação Hospitalar (SIH), referentes ao período entre 2008 a 2022, no Tocantins (TO). RESULTADOS: Foram notificadas 3.651 internações, sendo jovens de 20 a 29 anos o grupo etário mais acometido e homens o sexo com mais registros de internações. CONCLUSÃO: As fraturas de fêmur são lesões graves que afetam o osso da coxa e podem causar grande impacto na mobilidade e qualidade de vida do paciente, sendo fundamental medidas como alimentação adequada, suplementação de cálcio e vitamina D, prática regular de exercícios físicos
Palavras-chave: Fêmur; Fraturas; Epidemiologia.
Extending an Antiracism Lens to the Implementation of Precision Public Health Interventions
Authors: Allen Caitlin G. , Olstad Dana Lee , Kahkoska Anna R. , Guan Yue , Ramos Paula S. , Steinberg Julia , Staras Stephanie A. S. , Lumpkins Crystal Y. , Milko Laura V. , Turbitt Erin , Rahm Alanna K. , Saylor Katherine W. , Best Stephanie , Hatch Ashley , Santangelo Isabella , Roberts Megan C. 
Published: September 2023

Precision public health holds promise to improve disease prevention and health promotion strategies, allowing the right intervention to be delivered to the right population at the right time. Growing concerns underscore the potential for precision-based approaches to exacerbate health disparities by relying on biased data inputs and recapitulating existing access inequities. To achieve its full potential, precision public health must focus on addressing social and structural drivers of health and prominently incorporate equity-related concerns, particularly with respect to race and ethnicity. In this article, we discuss how an antiracism lens could be applied to reduce health disparities and health inequities through equity-informed research, implementation, and evaluation of precision public health interventions. (Am J Public Health. 2023;113(11):1210–1218. https://doi.org/10.2105/AJPH.2023.307386 )
A Transplant or a Patch? A Review of the Biologic Integration of Meniscus Allograft Transplantation
Authors: Lichtig Asher , Bedi Asheesh , Koh Jason , Amirouche Farid 
Published: September 2023

» After transplantation revascularization does occur although data are only available for animal models.» The time zero biomechanics, that is, the biomechanical properties at the time of transplant, of a meniscus allograft transplantation appear to appropriately mimic the original so long as the graft is sized correctly within 10% of the original and bone plug fixation is used.» Allograft type, that is, fresh vs. frozen, does not appear to affect the integration of the allograft.
NOT ENTIRELY ICHTHYOSAUR: A MYSTERIOUS LAMNIFORM AND ICHTHYOPTERYGIAN-FALL ASSOCIATION FROM THE ABYSSAL UPPER CRETACEOUS OF THE NORTHERN APENNINES (ITALY)
Authors: SERAFINI GIOVANNI , AMALFITANO JACOPO , DANISE SILVIA , MAXWELL ERIN E. , RONDELLI RICCARDO , PAPAZZONI CESARE A. 
Published: September 2023

ABSTRACT
Axial remains of a large ichthyosaur and a medium-sized anacoracid shark from the deep-water sediments of the Cenomanian of the Northern Apennines (Northern Italy) are described in detail. The specimens were found closely associated (less than 0.3 m apart), and offer an invaluable window into the taphonomy and dead-fall stages of pelagic vertebrates in a Mesozoic abyssal plain. The anacoracid shark remains, initially misinterpreted as an ichthyosaur, consist of eight articulated vertebrae embedded in a block of dark arenaceous matrix, and represent the first occurrence of an articulated shark from the Northern Apennines. The ichthyosaur remains consist of seven discoidal vertebrae and several unidentified fragments. Due to the absence of diagnostic skeletal elements, both specimens are assigned only at higher taxonomic levels. The two fossils, which come from the same outcrop and possibly from the same stratigraphic horizon, share a common taphonomic history, in terms of both their preservation and diagenesis. Mineralogy of the matrices of both is dominated by manganese micro-nodules, consistent with the deposition of polymetallic nodules in bathyal-abyssal settings. Biostratinomic processes that impacted the two specimens also provide insight on the development of Mesozoic marine vertebrate-falls in the deep-sea. Localized pyrite framboids inside the bone spongiosa are possible evidence of the sulfophilic stage (microbially mediated sulfur mobilization during lipid decay) in the ichthyosaur fall. Burrows assigned to Taenidium on the surface of the shark block, interpreted as worm-like feeding burrows or arthropod locomotion and feeding trails, might represent evidence of the enrichment opportunistic stage. Although intriguing, we have no evidence to support the hypothesis that this peculiar association of two pelagic predators is due to ecological interaction between the two animals.
Exploring global patterns of trace metal limitation as a regulator of the distribution of dominant marine phytoplankton groups
Authors: Zhang Qiong , Zhou Yu , Barton Samuel , Liu Fengjie , Shafiee Roxana , Yin Kedong , Bouman Heather , Tagliabue Alessandro , Rickaby Rosalind 
Published: September 2023

Abstract
The availability of essential elements determines the productivity of phytoplankton, with implications for ocean carbon sequestration, but the role of multiple trace metals for driving the biogeography of key phytoplankton groups that are major components of the carbon pump is not well understood. We explore the patterns of trace metal limitation of phytoplankton species spanning across different functional groups with a novel set of approaches that combined data synthesis and diagnostic modelling. Our analysis reinforces the importance of Fe, showing that representative species of diatoms, picocyanobacteria, and dinoflagellates are Fe limited in about 60%, 38%, and 5% of the global ocean. However, diatoms are also Mn limited in ~20% and dinoflagellates Zn limited in over 60% of the ocean. Our analyses additionally highlight a previously overlooked role of Cu in limiting the growth of phytoplankton and suggest that trace metal supply may have a greater impact on the distribution of diatoms and dinoflagellates than on coccolithophores. The inferred patterns of trace metal limitation for different phytoplankton are broadly supported by transcriptomic data from surface ocean. Using projections of how trace metal concentrations may evolve with climate change, we show that the future oceans may promote widespread Zn limitation, shifting phytoplankton communities to groups that drive a weaker biological pump.
Determining Malware Attacks in Iot Health Care System Using Self Attention Based Depth Poly O (Optimized)-network
Authors: Rodrigues Paul , Bangali Harun , Basha Syed Asif , Gopalakrishnan T , V Pandimurugan , S Rajasoundaran , SVN Santhosh Kumar 
Published: September 2023

Abstract
The Internet of Things (IoT) is becoming more important in numerous sectors, including healthcare, industry, the military, and education. The framework successfully safeguards the privacy, authenticity, and accessibility of data in a networked setting. Health care is only one of many sectors that may benefit from the given solutions, which are essential for protecting the personal information of patients and maintaining the integrity of their medical records. The privacy, security, and reliability of the whole health care system online are still at danger owing to a broad variety of intermediary assaults and infiltration activities, despite the fact that the Internet of Things (IoT) offers trustworthy mechanisms for keeping data secure. In this research, we employ a hyper-tuned optimal classifier based on deep learning to overcome these issues. Here the real time patients sensor data are retrieved and it can be preprocessed for removing the error by using the Minmax Hat normalization. Then the features can be selected using wrapper discriminant component analysis. Then the proposed classifier can be optimized using the Hybrid CUADA (Cuckoo Adam) optimization algorithm. After classification parameter optimization, the collected features are fed into the newly-introduced self-attention based depth poly O (optimized)-Network to detect malware intrusions and monitor patient records. The system's effectiveness has been assessed based on experimental findings and subsequent discussions.
Dimensional Structure and Psychometric Properties of the Persian Version of the Existential Loneliness Questionnaire (ELQ)
Authors: hadeei sohrab , Aminikhoo Masoumeh 
Published: September 2023

Abstract
Background: The recent pandemic of Coronavirus and its associated excess mortality, made the man more prone to sense of isolation and of being alone existentially. Therefore, it is necessary to identify, assess, and reduce such negative feelings. The present study aims to provide a Persian adaptation of the existential loneliness questionnaire (ELQ) and to examine its dimensional structure and psychometric characteristics.
Methods: The ELQ items were translated into Persian using forward-backward translation method. Participant recruitment is conducted via social media platform and data is collected via online survey. Content validity was evaluated by the experts‘ judgement, followed by factor analysis, validity, and reliability tests. Two samples of university students were collected. Sample 1 consisted of 305 students aged 18-53 years, completed the Persian adaptation of the ELQ and several other instruments: De Jong Gierveld Loneliness Scale (DJGLS), Existential Anxiety Questionnaire (EAQ), Beck Depression Inventory (BDI-13), Meaning in Life Questionnaire (MLQ), and Satisfaction with Life Scale (SWLS). Sample 2 consisted of 262 students aged 18-50 years, completed only the Persian ELQ to conduct Confirmatory Factor Analysis (CFA) tests.
Results: According to Parallel Analysis (PA) and Exploratory Factor Analysis (EFA) results, a unidimensional structure was found for the Persian ELQ. And the results of the CFA test supported this finding. The Multi-group CFA test supported the measurement invariance of the questionnaire across two samples. Evidence of high internal consistency (α =.91) and adequate test-retest reliability (r= .73) was found as well. The correlational analyses revealed strong construct validity based on the ELQ scores‘ significant association with other criterion measures.
Conclusions: According to the findings, the Persian version of the ELQ is a reliable, valid and psychometrically suitable instrument for use in Iranian samples of university students.
A Novel Rigid-Soft Gripper for Safe and Reliable Object Handling
Authors: Trinh Xuan Hiep , Nguyen Hoang-Hai , Pham Trung-Dung , My Chu Anh 
Published: September 2023

Abstract
This research paper proposes a novel robotic gripper that combines the advantages of both rigid and soft grippers. The challenge of developing robotic grippers that can handle a wide variety of objects with high precision, especially under harsh vibration is addressed. The gripper uses a main rigid structure for maintaining the stiffness of therobot hand and soft pads under air pressurization for handling the softly and flexibly the objects. The novel conceptual design and structural design are introduced. The gripper design and fabrication were validated through mathematical modelling, analysis, and experimental procedures. In particular, the deformation of the soft element is estimated using numerical simulation and mathematical calculation. Based on the estimation of the soft element’s deformation, the contact forceis analysed. The experiment confirms that the proposed gripper allows for safe interaction with a variety of grasped objects while maintaining diversity and stability during gripping movement, even under harsh vibration conditions with high frequency. This gripper design can be applied for handling a wide range of objects with varying sizes, masses, fragility, and placement positions. It is particularly useful when the gripping process necessitates both safe interaction and high reliability.