bluuebunny/crossref_metadata_2025_split huggingface dataset:
Transient stability analysis of DFIG-based wind farm-integrated power system considering gearbox ratio and reactive power control
Authors: Shabani Hamid Reza , Hajizadeh Amin , Kalantar Mohsen , Lashgari Mahmoud , Nozarian Mahdi 
Published: July 2023

AbstractNowadays, integration of large-scale wind farms (WFs) into power systems is experiencing rapid growth. As this rapid integration can affect transient stability significantly, employing doubly fed induction generator (DFIG)-based wind turbines, which have shown better behavior regarding system stability, has attracted much attention. This research contributes to the literature by investigating the transient stability of the power system with increasing penetration of DFIG-based WFs. In the proposed framework, the current-balance form is utilized for the network equations, and in this way, transient stability is performed using time-domain simulation. According to the simulation results, when the rate of wind power generation exceeds 0.7 per-unit, the increasing trend of the critical clearing time (CCT) is reversed and the CCT decreases greatly with the increased wind power penetration. In addition, the reactive power compensation by DFIG, the gearbox ratio, the power system strength, and DFIG parameters are comprehensively investigated as effective parameters on transient stability. Since the rated rotor speed of DFIG significantly impacts the electrical torque and machine currents, the reduction of the rated rotor speed due to the change of the gearbox ratio has been investigated as one of the effective factors to improve the transient stability. The simulation results demonstrate the effectiveness of the proposed approach in improving power system transient stability.
High-temperature behavior of quartz-in-garnet system revealed by in situ Raman spectroscopy
Authors: Morana Marta , Angel Ross J. , Alvaro Matteo , Mihailova Boriana 
Published: July 2023

AbstractQuartz is one of the most abundant minerals in the Earth crust and therefore quartz inclusions in garnet are of great interest for elastic geobarometry, an approach that exploits the elastic properties of the mineral pair to back-calculate the conditions of inclusion entrapment. However, the high-temperature behavior of quartz inclusions close to the $$\alpha$$
α
–$$\beta$$
β
transition boundary has not been studied experimentally. We have therefore performed in situ high-temperature Raman spectroscopy on a quartz-in-garnet system up to 1000 K, and have also collected an improved reference data set for the temperature dependence of the Raman scattering of free quartz. Our results show that the $$\alpha$$
α
-to-$$\beta$$
β
phase transition is hindered by the stress imposed by the host on the quartz inclusion, resulting in a thermosalient effect of the whole host-inclusion system or a mechanical cracking of the host mineral.
Experience and perceptions among rheumatoid arthritis patients following a telehealth-delivered dietary intervention: a qualitative study
Authors: Raad Tala , Griffin Anne , George Elena S. , Larkin Louise , Fraser Alexander , Kennedy Norelee , Tierney Audrey 
Published: July 2023

AbstractThe effects of dietary modifications have been assessed in people living with rheumatoid arthritis (RA) with consistent benefits reported from clinical trials. However, the lived experience of making and sustaining positive dietary changes for people with RA remains unknown. The aim of this qualitative study was to explore the experiences of adults with RA and their perceptions of a 12-week telehealth-delivered dietary intervention and to assess the acceptability of the programme. Qualitative data was collected via four online focus groups with participants who had just completed a 12-week dietary intervention programme delivered through telehealth methods. Thematic analysis was used to code and summarize the identified key themes. Twenty-one adults with RA (47.5 ± 12.3 years, 90.5% females) were included in this qualitative study. Overarching themes included: (a) motivation to join the programme, (b) benefits of the programme, (c) factors influencing adherence to dietary prescription, and (d) advantages and disadvantages of telehealth. The study demonstrated that a dietary intervention delivered through telehealth methods by a Registered Dietitian (RD) appears to be well-accepted and may be used to complement face-to-face care for people with RA. The identified factors influencing the adoption of a healthier eating pattern will aid in the development of future dietary interventions for a RA population.
On efficiency in disagreement economies
Authors: Heyerdahl-Larsen Christian , Walden Johan 
Published: July 2023

AbstractWe analyze multiple-beliefs based efficiency measures in economies with risk and disagreement, including belief neutral efficiency and inefficiency, incomplete knowledge efficiency, efficiency based on unanimity, and utility aggregators that minimize Bergson welfare functions over multiple beliefs. We provide equivalence results under technical conditions that are satisfied in several work-horse economies, including the exchange economy and a standard economy with a linear production technology. We also provide several examples for which these measures differ. Our results show that the further away one gets from the standard exchange economy, the more the different multiple-beliefs based measures differ in the allocations they identify as efficient, in general. Consequently, the more important the choice of efficiency measure becomes.
CAS FGOALS-f3-L Model Datasets for CMIP6 DCPP Experiment
Authors: Hu Shuai , Wu Bo , Wang Yiming , Zhou Tianjun , Yu Yongqiang , He Bian , Lin Pengfei , Bao Qing , Liu Hailong , Chen Kangjun , Zhao Shuwen 
Published: July 2023

AbstractThe outputs of the Chinese Academy of Sciences (CAS) Flexible Global Ocean-Atmosphere-Land System (FGOALS-f3-L) model for the decadal climate prediction project (DCPP) of the Coupled Model Intercomparison Project Phase 6 (CMIP6) are described in this paper. The FGOALS-f3-L was initialized through the upgraded, weakly coupled data assimilation scheme, referred to as EnOI-IAU, which assimilates observational anomalies of sea surface temperature (SST) and upper-level (0–1000-m) ocean temperature and salinity profiles into the coupled model. Then, nine ensemble members of 10-year hindcast/forecast experiments were conducted for each initial year over the period of 1960–2021, based on initial conditions produced by three initialization experiments. The hindcast and forecast experiments follow the experiment designs of the Component-A and Component-B of the DCPP, respectively. The decadal prediction output datasets contain a total of 44 monthly mean atmospheric and oceanic variables. The preliminary evaluation indicates that the hindcast experiments show significant predictive skill for the interannual variations of SST in the north Pacific and multi-year variations of SST in the subtropical Pacific and the southern Indian Ocean.
Chest configuration in children and adolescents with infantile nephropathic cystinosis compared with other chronic kidney disease entities and its clinical determinants
Authors: Müller Sophia , Kluck Rika , Jagodzinski Celina , Brügelmann Malina , Hohenfellner Katharina , Büscher Anja , Kemper Markus J. , Fröde Kerstin , Oh Jun , Billing Heiko , Thumfart Julia , Weber Lutz T. , Acham-Roschitz Birgit , Arbeiter Klaus , Tönshoff Burkhard , Hagenberg Martina , Pavičić Leo , Haffner Dieter , Zivicnjak Miroslav 
Published: July 2023

Abstract
Background
Infantile nephropathic cystinosis (INC) is a systemic lysosomal storage disease causing intracellular cystine accumulation, resulting in renal Fanconi syndrome, progressive kidney disease (CKD), rickets, malnutrition, and myopathy. An INC-specific disproportionately diminished trunk length compared to leg length poses questions regarding the functionality of the trunk.

Methods
Thus, we prospectively investigated thoracic dimensions and proportions, as well as their clinical determinants in 44 pediatric patients with INC with CKD stages 1–5 and 97 age-matched patients with CKD of other etiology between the ages of 2–17 years. A total of 92 and 221 annual measurements of patients with INC and CKD, respectively, were performed, and associations between anthropometric and clinical parameters were assessed using linear mixed-effects models.

Results
Patients with INC exhibited altered chest dimensions that were distinct from CKD controls, characterized by markedly increased chest depth to height and chest depth to chest width ratio z-scores (> 1.0), while those of patients with CKD were only mildly affected (z-score within ± 1.0). Ratio z-scores differed significantly between both patient groups from 2–6 years of age onward. The degree of chest disproportion in INC patients was significantly associated with both the degree of CKD and tubular dysfunction (e.g., low serum phosphate and bicarbonate) across three different age groups (2–6, 7–12, and 13–17 years).

Conclusion
Our data show an INC-specific alteration in thoracic shape from early childhood onward, which is distinct from CKD of other etiologies, suggesting early childhood subclinical changes of the musculoskeletal unit of the thoracic cage, which are associated with kidney function.

Graphical abstract
The effective threshold dose of etanercept in patients with methotrexate-resistant rheumatoid arthritis
Authors: Chen Fangfang , Lang Yitian , Geng Shikai , Wang Xiaodong , Lu Liangjing , Ye Shuang , Zhang Le , Li Ting 
Published: July 2023

Abstract
Introduction

The therapy of rheumatoid arthritis (RA) was advanced by biological agents, yet costly. This study aims to identify the effective threshold dose of etanercept (ENT) and cost-effectiveness in methotrexate (MTX)-resistant RA in real world.

Methods
Eligible patients had an inadequate response (DAS28-ESR > 3.2) to initial MTX monotherapy, and subsequently received etanercept. The effective cut-off value of cumulative dose was identified to maintain remission response (DAS28-ESR < 2.6) at month 24 by using restricted cubic splines. Remission rate, low disease activity (LDA) rate, glucocorticoid exposure, safety, and cost-effectiveness were compared between the saturated and non-saturated dose groups divided by the cut-off dose.

Results
Seventy-eight (14.2%) of 549 enrolled patients were eligible, and 72 patients completed follow-up. The 2-year cumulative cut-off dose that maintained remission response at 24 months was 1975 mg. And the recommended threshold dosing strategy of etanercept was twice weekly (BIW) for the first 6 months, every week (QW) for the next 6 months, and every 2 weeks (Q2W) and every month (QM) for the second year. Greater net changes in DAS28-ESR score were observed in the ENT saturated dose group than in the non-saturated dose group (average change 0.569, 95%CI 0.236–0.901, p = 0.001). The proportion of patients achieving remission (27.8% vs 72.2%, p < 0.001) and LDA (58.3% vs 83.3%, p = 0.020) in the non-saturated group was both significantly lower than that in the saturated group at 24 months. The incremental cost-effectiveness ratio of the saturated group referred to the non-saturated group was 5791.2 $/QALY.

Conclusions
In refractory RA patients, the effective cumulative cut-off dose of etanercept for sustained remission at 24 months was calculated as 1975 mg, and receiving saturated dose was more effective and cost-effective than with non-saturated dose.

Key Points• The effective cumulative cut-off dose of etanercept for sustained remission at 24 months in RA patients is calculated as 1975 mg.• Receiving saturated dose of etanercept is more effective and cost-effective than with non-saturated dose in refractory RA patients.
Tropical medians by transportation
Authors: Comăneci Andrei , Joswig Michael 
Published: July 2023

AbstractFermat–Weber points with respect to an asymmetric tropical distance function are studied. It turns out that they correspond to the optimal solutions of a transportation problem. The results are applied to obtain a new method for computing consensus trees in phylogenetics. This method has several desirable properties; e.g., it is Pareto and co-Pareto on rooted triplets.
Identification of RNA-binding protein YBX3 as an oncogene in clear cell renal cell carcinoma
Authors: Wang Chen , You Zhijie , He Yihui , Chen Xin 
Published: July 2023

AbstractY box binding protein 3 (YBX3) is an indispensable factor for protein synthesis, cellular growth, and proliferation, and is intricately involved in the progression of diverse tumor types. The objective of the current study was to investigate the role of YBX3 in the prognosis, immune infiltration, and progression of clear cell renal clear cell carcinoma (ccRCC). The expression level of YBX3 in ccRCC tissues was compared using The Cancer Genome Atlas (TCGA) and analyzed using the Wilcoxon rank sum test. Logistic regression and multivariate Cox analyses were subsequently employed to scrutinize the association between YBX3 expression and the clinicopathological characteristics of patients. The TIMER 2.0 tool was also utilized to quantify the degree of immune cell infiltration of YBX3. Kaplan Meier analysis was performed to assess the correlation between YBX3 and the survival rate. A high expression level of YBX3 was significantly correlated with the tumor pathological stage, histological grade, TNM stage, and the abundance of aDC, pDC, Th1, and Treg immune cells. Higher expression of YBX3 in advanced ccRCC was found to be associated with a lower overall survival rate in the M0, N0, and T2 subgroups. In vitro, after the silencing of YBX3 in A498 cells and overexpression of YBX3 in ACHN cells, cell proliferation, colony formation, migration, invasion, cell cycle assays, and flow cytometric apoptotic analysis were performed to evaluate the role of YBX3 in the progression of ccRCC. YBX3 was found to be intricately associated with the progression and prognosis of ccRCC, and may serve as an effective treatment target for ccRCC or a biomarker for prognosis prediction.
Change of the surface and structure of activated carbon as a result of HNO3 modification
Authors: Wolak Eliza , Orzechowska-Zięba Agnieszka 
Published: July 2023

AbstractIn the paper the chemical modification of activated carbon was presented. The activated carbon was modified by nitric acid. For the tested activated carbons, the following physical and chemical properties were determined: bulk density, pH of the water extract, and effective diameter of the grains. Elemental and technical analyses were performed. The pore distribution was determined using mercury porosimetry. Low-temperature nitrogen isotherms were used to analyze the microporous structure. The chemical properties of the surfaces of the tested adsorbents were interpreted by means of the Boehm method. The water vapor adsorption isotherms at 303 K were determined and the adsorption capacity towards methanol was tested using the desiccator method. Thermogravimetric tests were used and, at the same time, the released oxidizing gases from the tested samples were analyzed using a mass spectrometer. As a result of the modification, activated carbon enriched with acidic oxygen functional groups was obtained. The resulting modified activated carbon showed worse structural parameters (when compred to umodified activated carbon), however it was characterized by a higher adsorption capacity in relation to polar adsorbates such as water and methanol, especially in the low pressure range.
A Critical Review of the Literature Regarding the Selection of Long-Term Romantic Partners
Authors: Devenport Scott , Davis-McCabe Catriona , Winter Sam 
Published: July 2023

AbstractResearch regarding how people choose their long-term romantic partners is extensive, but the understanding of the psychological processes behind these choices, and predicting who people choose, is elusive. This review attempts to examine potential reasons for this elusive nature by first outlining the current state of the literature and then highlighting issues within the current paradigm. First among these issues is a focus on singular perspectives and little attempt to integrate these perspectives with others. Second, many studies focus on increasingly complex designs to explore the predictive utility of trait preferences, attempts which have had only limited success. Third, novel findings appear to be unintegrated with established findings, leaving the potential combination of these ideas unrealized. Finally, long-term romantic partner selection is a complex psychological phenomenon, but current theory and research methodologies are not sufficiently addressing this complexity. This review concludes with suggestions for future research direction, including a focus on the psychology behind the partner selection process and the potential of qualitative enquiry to reveal novel pathways behind these psychological processes. There is a need for an integrative framework that permits the coexistence of established and novel ideas, and multiple perspectives, from both current and future research paradigms.
Simulation of the E-Defense 2015 test on a 10-storey building using macro-models
Authors: Janevski Antonio , Kang Jae-Do , Isaković Tatjana 
Published: July 2023

AbstractThe capabilities of certain standard macro numerical models were evaluated by simulating a shaking table experiment that was performed on a full-scale ten-storey fixed-base building with a frame and dual structural system in two perpendicular directions (denoted as the frame and wall directions) at the largest shaking table in the E-Defense centre in Japan. The lumped plasticity model for columns and beams, the multiple-vertical-line-element model for walls and the scissors model for beam-column joints were evaluated. The results indicated that the experiment was simulated reasonably well. The most significant discrepancy was observed between the maximum drifts along the wall direction in the strongest cycle of the strongest test (calculated drift of 1.9% versus measured drift of 1.5%). In other cycles and tests, these differences were smaller. The calculated and measured maximum accelerations along the wall direction in the strongest test were 13.8 m/s2and 13.5 m/s2, respectively. The discrepancy between the analysis and experiment results was smaller along the frame direction. The maximum calculated and measured drifts were 2.9% and 3.1%, respectively. The maximum calculated and measured accelerations were 15.8 m/s2and 19.0 m/s2, respectively. In general, the standard input parameters were used in the evaluated models. However, some parameters required modifications, particularly when modelling weakly reinforced beam-column joints with substandard reinforcement that were considerably damaged. Their yielding rotation and near-collapse strength were, on average, reduced to 55% and 30% of the standard value, respectively. One of the most important parameters influencing the response was the effective width of the slabs, which was increased to the total span length for the highly loaded beams. The ratios of the strength, stiffness and amount of dissipated energy in the joints, beams and columns also significantly influenced the response. The adequate ratio of the dissipated energy was obtained by reducing the standard unloading stiffness in the beams and columns. The initial stiffness considerably influenced the response, particularly under weaker excitations. This stiffness was reduced threefold to account for various factors that typically reduce its value, which, among others, includes the influence of preceding tests on the same building with sliding foundations, as well as the assembly, transportation and handling of the specimen.
Solid-state 13C NMR, X-ray diffraction and structural study of methyl 4-O-methyl β-D-glucopyranosides with all eight possible methyl-substitution patterns
Authors: Yoneda Yuko , Kawada Toshinari , Bacher Markus , Prado-Roller Alexander , Hettegger Hubert , Potthast Antje , French Alfred D. , Rosenau Thomas 
Published: July 2023

AbstractCellulose model compounds that mimic the building blocks of modified cellulose and cellulose derivatives are widely used in cellulose research to infer the properties of the polymer from the monomer. Based on the well-established model compound methyl 4-O-methyl β-d﻿-glucopyranoside, in which the methyl groups represent the truncated side chains of the cellulose, the corresponding O-methyl-substituted derivatives with all eight different substitution patterns (mono-, di- and trisubstituted at O-2, O-3, O-6) were synthesized. Crystallization of the products in sufficient quality for solid-state structure determination by single-crystal X-ray diffraction succeeded in all cases, and the results are reported. Two of the compounds showed more than one independent molecule per unit cell. Solid-state 13C NMR showed a significant down-field shift (5–10 ppm) of the OMe-substituted carbons relative to the OH-substituted counterparts and generally confirmed the important influence of solid-state packing on the chemical shifts as seen by comparison to the solution NMR data.
Graphical abstract
BMECs Ameliorate High Glucose-Induced Morphological Aberrations and Synaptic Dysfunction via VEGF-Mediated Modulation of Glucose Uptake in Cortical Neurons
Authors: Huang Yu-Qi , Gu Xiao , Chen Xiao , Du Yi-Ting , Chen Bin-Chi , Sun Feng-Yan 
Published: July 2023

AbstractIt has been demonstrated that diabetes cause neurite degeneration in the brain and cognitive impairment and neurovascular interactions are crucial for maintaining brain function. However, the role of vascular endothelial cells in neurite outgrowth and synaptic formation in diabetic brain is still unclear. Therefore, present study investigated effects of brain microvascular endothelial cells (BMECs) on high glucose (HG)-induced neuritic dystrophy using a coculture model of BMECs with neurons. Multiple immunofluorescence labelling and western blot analysis were used to detect neurite outgrowth and synapsis formation, and living cell imaging was used to detect uptake function of neuronal glucose transporters. We found cocultured with BMECs significantly reduced HG-induced inhibition of neurites outgrowth (including length and branch formation) and delayed presynaptic and postsynaptic development, as well as reduction of neuronal glucose uptake capacity, which was prevented by pre-treatment with SU1498, a vascular endothelial growth factor (VEGF) receptor antagonist. To analyse the possible mechanism, we collected BMECs cultured condition medium (B-CM) to treat the neurons under HG culture condition. The results showed that B-CM showed the same effects as BMEC on HG-treated neurons. Furthermore, we observed VEGF administration could ameliorate HG-induced neuronal morphology aberrations. Putting together, present results suggest that cerebral microvascular endothelial cells protect against hyperglycaemia-induced neuritic dystrophy and restorate neuronal glucose uptake capacity by activation of VEGF receptors and endothelial VEGF release. This result help us to understand important roles of neurovascular coupling in pathogenesis of diabetic brain, providing a new strategy to study therapy or prevention for diabetic dementia.
Graphical Abstract
Hyperglycaemia induced inhibition of neuronal glucose uptake and impaired to neuritic outgrowth and synaptogenesis. Cocultured with BMECs/B-CM and VEGF treatment protected HG-induced inhibition of glucose uptake and neuritic outgrowth and synaptogenesis, which was antagonized by blockade of VEGF receptors. Reduction of glucose uptake may further deteriorate impairment of neurites outgrowth and synaptogenesis.