bluuebunny/crossref_metadata_2025_split huggingface dataset:
Parity, dental caries and implications for maternal depletion syndrome in northern Nigerian Hausa women
Authors: Oziegbe Elizabeth O. , Schepartz Lynne A. 
Published: March 2023

Background
Female reproductive history, especially high parity, affects general health and may impact negatively on oral health. While parity has been positively linked to tooth loss, the specific association between parity and caries has not been adequately investigated.

Aim
To determine the association between parity and caries in a population of higher parity women. Influences of likely confounders (age, socio-economic status, reproductive parameters, oral health practices and sugar consumption between meals) were considered.

Methods
This was a cross-sectional study involving 635 Hausa women of varying parity aged 13–80 years. Socio-demographic status, oral health practices and sugar consumption were obtained using a structured interviewer-administered questionnaire. All decayed, missing and filled teeth due to caries (excluding third molars) were noted, and tooth loss etiology was queried. Associations with caries were evaluated through correlation, ANOVA, post hoc analyses and Student’s t tests. Effect sizes were considered for magnitude of differences. Multiple regression (binomial model) was used to investigate predictors of caries.

Results
Hausa women had a high prevalence of caries (41.4%) despite low sugar consumption; nonetheless the overall mean DMFT score was very low (1.23 ± 2.42). Older, higher parity women experienced more caries, as did those with longer reproductive spans. Additionally, poor oral hygiene, use of fluoride toothpaste and frequency of sugar consumption were significantly associated with caries.

Conclusion
Higher parity (>6 children) was associated with higher DMFT scores. These results suggest that a form of maternal depletion, expressed as heightened caries susceptibility and subsequent tooth loss, occurs with higher parity.
Short-term heat acclimation protocols for an aging population: Systematic review
Authors: Cole Edward , Donnan Kate J. , Simpson Andrew J. , Garrett Andrew T. 
Published: March 2023

Introduction
Elderly and sedentary individuals are particularly vulnerable to heat related illness. Short-term heat acclimation (STHA) can decrease both the physical and mental stress imposed on individuals performing tasks in the heat. However, the feasibility and efficacy of STHA protocols in an older population remains unclear despite this population being particularly vulnerable to heat illness. The aim of this systematic review was to investigate the feasibility and efficacy of STHA protocols (≤twelve days, ≥four days) undertaken by participants over fifty years of age.

Methods
Academic Search Premier, CINAHL Complete, MEDLINE, APA PsycInfo, and SPORTDiscus were searched for peer reviewed articles. The search terms were; (heat* or therm*) N3 (adapt* or acclimati*) AND old* or elder* or senior* or geriatric* or aging or ageing. Only studies using primary empirical data and which included participants ≥50 years of age were eligible. Extracted data includes participant demographics (sample size, gender, age, height, weight, BMI and V.O2max), acclimation protocol details (acclimation activity, frequency, duration and outcome measures taken) and feasibility and efficacy outcomes.

Results
Twelve eligible studies were included in the systematic review. A total of 179 participants took part in experimentation, 96 of which were over 50 years old. Age ranged from 50 to 76. All twelve of the studies involved exercise on a cycle ergometer. Ten out of twelve protocols used a percentage of V.O2max or V.O2peak to determine the target workload, which ranged from 30% to 70%. One study-controlled workload at 6METs and one implemented an incremental cycling protocol until Tre was reached +0.9°C. Ten studies used an environmental chamber. One study compared hot water immersion (HWI) to an environmental chamber while the remaining study used a hot water perfused suit. Eight studies reported a decrease in core temperature following STHA. Five studies demonstrated post-exercise changes in sweat rates and four studies showed decreases in mean skin temperature. The differences reported in physiological markers suggest that STHA is viable in an older population.

Conclusion
There remains limited data on STHA in the elderly. However, the twelve studies examined suggest that STHA is feasible and efficacious in elderly individuals and may provide preventative protection to heat exposures. Current STHA protocols require specialised equipment and do not cater for individuals unable to exercise. Passive HWI may provide a pragmatic and affordable solution, however further information in this area is required.
Diagnostic performances of Schistosoma haematobium and Schistosoma mansoni recombinant proteins, peptides and chimeric proteins antibody based tests. Systematic scoping review
Authors: Vengesai Arthur , Muleya Victor , Midzi Herald , Tinago Tryphine Vimbai , Chipako Isaac , Manuwa Marble , Naicker Thajasvarie , Mduluza Takafira 
Published: March 2023

Background
Traditional diagnostic tests for schistosome infections are suboptimal, particularly when the parasite burden is low. In the present review we sought to identify recombinant proteins, peptides, and chimeric proteins with potential to be used as sensitive and specific diagnostic tools for schistosomiasis.

Methods
The review was guided by PRISMA-ScR guidelines, Arksey and O’Malley’s framework, and guidelines from the Joanna Briggs Institute. Five databases were searched: Cochrane library, PubMed, EMBASE, PsycInfo and CINAHL, alongside preprints. Identified literature were assessed by two reviewers for inclusion. A narrative summary was used to interpret the tabulated results.

Results
Diagnostic performances were reported as specificities, sensitivities, and AUC. The AUC for S. haematobium recombinant antigens ranged from 0.65 to 0.98, and 0.69 to 0.96 for urine IgG ELISA. S. mansoni recombinant antigens had sensitivities ranging from 65.3% to 100% and specificities ranging from 57.4% to 100%. Except for 4 peptides which had poor diagnostic performances, most peptides had sensitivities ranging from 67.71% to 96.15% and specificities ranging from 69.23% to 100%. S. mansoni chimeric protein was reported to have a sensitivity of 86.8% and a specificity of 94.2%.

Conclusion
The tetraspanin CD63 antigen had the best diagnostic performance for S. haematobium. The tetraspanin CD63 antigen Serum IgG POC-ICTs had a sensitivity of 89% and a specificity of 100%. Peptide Smp_150390.1 (216–230) serum based IgG ELISA had the best diagnostic performance for S. mansoni with a sensitivity of 96.15% and a specificity of 100%. Peptides were reported to demonstrate good to excellent diagnostic performances. S. mansoni multi-peptide chimeric protein further improved the diagnostic accuracy of synthetic peptides. Together with the advantages associated with urine sampling technique, we recommend development of multi-peptide chimeric proteins urine based point of care tools.
Polypoid Gastric Adenomyoma: A Rare Cause of Bleeding Treated With Polypectomy
Authors: Shah Ayushi , Ahmed Zunirah , Ro Jae Y. , Ergun Gulchin A. 
Published: March 2023

ABSTRACT
Gastric adenomyoma is a rare tumor composed of smooth muscle fibers and glandular tissue. Usual presentations include nausea, bloating, and gastric outlet obstruction. We describe a case of a 60-year-old woman who presented with abdominal pain and melena. Endoscopy showed a 1.5 cm polyp in the stomach body that was resected using snare polypectomy. Biopsy showed glands mixed with fibromuscular tissue consistent with gastric adenomyoma. We conclude that gastric adenomyoma, although rare, may present as a bleeding polyp in the stomach body and may be treated with excisional polypectomy.
Cap Polyposis: An Elusive Diagnosis in a Pediatric Patient Successfully Managed With Endoscopic Treatment
Authors: Tomar Sanjeevani , Maksimak Martin , Diehl David L. 
Published: March 2023

ABSTRACT
Cap polyposis is a rare condition of the rectum or sigmoid colon manifested by inflammatory polyps covered by a thick layer of fibrinopurulent mucus. This condition typically presents as mucoid diarrhea and rectal bleeding, and patients are often prescribed antibiotics (such as those for Helicobacter pylori), steroids, infliximab, or aminosalicylates. Surgical management is an option for unresponsive disease, but endoscopic management has been rarely reported. For cases of cap polyposis in which conservative medical management fails, wide-field endoscopic mucosal resection is a viable option.
Progressive Cholestasis and Biliary Cirrhosis After Initiating Oral Semaglutide: Report From the Drug-Induced Liver Injury Network
Authors: Ma Jiayi , Mathur Karan , Muldoon Jessica L. , Ghabril Marwan , Chalasani Naga , Vuppalanchi Raj 
Published: March 2023

ABSTRACT
Semaglutide has little hepatic metabolism and is deemed low risk for causing drug-induced liver injury (DILI). We present a case of DILI from the US DILI Network. The case involved a 51-year-old man with type 2 diabetes who presented with jaundice and acute-on-chronic kidney disease 6 months after starting oral semaglutide. His liver injury progressed to biliary cirrhosis, accompanied by nephritis that led to end-stage renal disease. Extensive evaluations including liver and kidney biopsies revealed no alternative etiologies. Cholestatic gene sequencing revealed heterozygosity for ABCC2 and DHCR7. He eventually underwent combined liver and kidney transplantation.
Clash of the -itises: An Unexpected Case of Sigmoid Colon Vasculitis
Authors: Vigna Carolina , Wang Stephen H. , Ore Ana Sofia , Eickel Grant , Messaris Evangelos 
Published: March 2023

ABSTRACT
Vasculitis is an inflammatory process of the blood vessels, characterized by leukocyte infiltration in the vessel wall and reactive damage to the mural structures. They have a wide clinical spectrum and can present in a localized or systemic manner. Colonic involvement primarily manifests as abdominal pain and rectal bleeding. Less commonly, it can be associated with colonic perforation or anastomotic leakage after colorectal surgery. We report a case of a 42-year-old man with a history of HIV and proctocolitis who presented with an unexpected vasculitis of the sigmoid colon.
Candida Esophagitis Presenting as an Esophageal Pseudotumor
Authors: Frost S. Taylor , Abdelfattah Thaer , Shah Tilak U. 
Published: March 2023

ABSTRACT
The typical appearance of Candida esophagitis is white plaque-like membranes within the esophagus. We describe a unique case of Candida esophagitis that presented as a bulky, malignant-appearing, positron emission tomography-computed tomography-avid mass on endoscopy. Esophageal candidiasis persisted despite a standard course of antifungal medications (fluconazole 400 mg daily for 14 days), and eradication was successful only after fluconazole 800 mg daily was administered. Malignancy was excluded based on 2 separate sessions of endoscopy with multiple biopsies and finally with endoscopic full-thickness resection assisted by preresection closure with an over-the-scope clip.
Refractory Checkpoint Inhibitor Colitis Responsive to Ustekinumab
Authors: Perez Del Nogal Genesis , Patel Neha 
Published: March 2023

ABSTRACT
Immune checkpoint inhibitors have transformed the treatment of cancer. Nonetheless, multiple immune-related adverse events have been reported, including checkpoint inhibitor colitis. Severe colitis can be complicated by ileus, megacolon, intestinal perforation, and death. Current appropriate treatment includes steroids, followed by antitumor necrosis factor biologic therapy, infliximab. Alternatively, vedolizumab and fecal microbiota transplantation have reported efficacy for refractory cases. In this study, we present the first case report of a patient with steroid-refractory checkpoint inhibitor-induced colitis due to pembrolizumab for Stage IV anaplastic thyroid carcinoma successfully treated with ustekinumab after failure of infliximab, vedolizumab, and fecal microbiota transplantation. This may lead to a better understanding of treatment options for refractory checkpoint inhibitor colitis.
Form, Materiality, and Symbolism in Non-Arabic Muslim Arts: A Case Study from Indonesian Wayang Performance
Authors: Lutfianto Lutfianto , Junaidi Junaidi 
Published: March 2023

The puppet theater becomes a popular form of cultural expression in the Muslim world, even though wayang performances are not considered a central part of Islamic theology. Wayang performances are seen as having a spiritual significance among Indonesian Muslims for centuries. Such puppet theater incorporates forms, styles, and elements of Islamic spirituality and traditional Javanese cultural practices into its narratives. The article pays attention to the idiosyncratic forms, elements, and meanings of contemporary wayang through the craftsman’s framework. The analysis takes into account the formulation and presentation of the wayang in contemporary Indonesian art, focusing on the creation of “Wayang Kekayon Khalīfah Paraga Umar ibn al-Khaṭṭāb.” This wayang is associated with the figure of Umar b. Khaṭṭab (d. 644). Umar is a historical figure who played a significant role in the early history of Islam and is revered for his wisdom and leadership by most Muslims. The discussion argues that the materiality of puppets in the non-Arab Muslim world not only functions as a traditional form of entertainment stimulating the sense of “fun” but also as complex semiotic experiences between a dalang (wayang puppeteer) and his audiences using signs of two-dimensional buffalo leather and its silhouettes.
Pengaruh Dukungan Orang Dekat terhadap Kepatuhan Minum Obat pada Orang dengan HIV/AIDS (ODHA) di Kabupaten Madiun
Authors: Kartini Puri Ratna , Wisnubroto Agung Prabowo , Putri Yovita Aprilia 
Published: March 2023

Background: The proper and correct ARV therapy requires social support, especially from family and close people, in order to be able to reduce negative impacts of the infection.Methods: This study is an observational-analytic study to analyze the influence of support from close people for adherence to taking ARV drugs in PLWH in Madiun district. The research design used in this study was cross sectional with purposive sampling technique. Data was taken through interviews with respondents without giving any treatment. The sample in this study were patients who had been diagnosed with HIV positive for more than 6 months in 2018 which was randomly selected. The research location is the working area of the Local AIDS Eradication Commission (KPAD) of Madiun district. The study was conducted for 7 months, starting from June to December 2018.Result: From the results of bivariate analysis, it was concluded that the support from close people has influence on medication adherence in PLHIV (p = 0.000).Conclusion : From this research, it is expected to be an input for the government in determining health policy, especially to increase the rate of compliance with medication for PLWHA in Madiun district.
Keberadaan Residu Tetrasiklin pada Daging Ayam Broiler di Kabupaten Kudus (Studi di Pasar Tradisional dan Pasar Modern Tahun 2019)
Authors: Aulia Sabilla Ananda , Sutiningsih Dwi , Setyawan Henry , Udiyono Ari 
Published: March 2023

Background: One of the causes of antibiotic resistance is the presence of antibiotic residues in livestock, one of which is broiler chicken meat. Excessive use of antibiotics and not in accordance with the diagnosis will result in the discovery of antibiotic residue content in chicken meat and will endanger public health. The purpose of this study was to determine the description of the antibiotic residues of tetracycline in broiler chicken meat sold in traditional and modern markets in Jati District, Kudus Regency.Methods: This type of research is a descriptive observational study with a cross-sectional approach. The samples in this study were all broiler chicken meat sold in traditional markets (Bitingan Market, Sunggingan Ploso Market, and Baru Market) and in the modern Hypermart market with a total sample of 78 samples of broiler chicken meat taken with total population sampling technique. Sample testing was carried out at Balai Veteriner Boyolali using the Bioassay method.Result: Based on the results of the study, there is no tetracycline antibiotic residues were found in 78 (100%) broiler chicken meats sold in the Bitingan Market, Sunggingan Ploso Market, Baru Market, and Hypermart.Conclusion : There is no tetracycline antibiotic residues were found in broiler chicken meat sold in the Bitingan Market, Sunggingan Ploso Market, Baru Market, and Hypermart.
Existence and multiplicity of solutions for a quasilinear system with locally superlinear condition
Authors: Liu Cuiling , Zhang Xingyong 
Published: March 2023

Abstract
We investigate the existence and multiplicity of weak solutions for a nonlinear Kirchhoff type quasilinear elliptic system on the whole space

R

N

{{\mathbb{R}}}^{N}

. We assume that the nonlinear term satisfies the locally super-

(

m

1

,

m

2

)

\left({m}_{1},{m}_{2})

condition, that is,

lim

∣

(

u
,
v

)

∣
→
+
∞

F

(

x
,
u
,
v

)

∣
u

∣

m

1

+
∣
v

∣

m

2

=
+
∞

{\mathrm{lim}}_{| \left(u,v)| \to +\infty }\frac{F\left(x,u,v)}{| u{| }^{{m}_{1}}+| v{| }^{{m}_{2}}}=+\infty

for a.e.

x
∈
G

x\in G

, where

G

G

is a domain in

R

N

{{\mathbb{R}}}^{N}

, which is weaker than the well-known Ambrosseti-Rabinowitz condition and the naturally global restriction,

lim

∣

(

u
,
v

)

∣
→
+
∞

F

(

x
,
u
,
v

)

∣
u

∣

m

1

+
∣
v

∣

m

2

=
+
∞

{\mathrm{lim}}_{| \left(u,v)| \to +\infty }\frac{F\left(x,u,v)}{| u{| }^{{m}_{1}}+| v{| }^{{m}_{2}}}=+\infty

for a.e.

x
∈

R

N

x\in {{\mathbb{R}}}^{N}

. We obtain that the system has at least one weak solution by using the classical mountain pass theorem. To a certain extent, our theorems extend the results of Tang et al. [Nontrivial solutions for Schrodinger equation with local super-quadratic conditions, J. Dynam. Differ. Equ. 31 (2019), no. 1, 369–383]. Moreover, under the aforementioned naturally global restriction, we obtain that the system has infinitely many weak solutions of high energy by using the symmetric mountain pass theorem, which is different from those results of Wang et al. [Existence and multiplicity of solutions for a class of quasilinear elliptic systems in Orlicz-Sobolev spaces, J. Nonlinear Sci. Appl. 10 (2017), no. 7, 3792–3814] even if we consider the system on the bounded domain with Dirichlet boundary condition.
Intensification of thorium biosorption onto protonated orange peel using the response surface methodology
Authors: Ghorbanpour Khamseh Ali A. , Amini Younes , Shademan Mohammad Mahdi , Ghazanfari Valiyollah 
Published: March 2023

Abstract
In this research work, intensifying the possibility of protonated orange peel to uptake thorium (IV) ions from aqueous solutions in a batch system was investigated and optimized using the response surface methodology. The effect of three independent process variables including thorium initial concentration, pH, and biosorbent dosage was assessed based on the central composite design. The validity of the quadratic model was verified by the coefficient of determination. The optimization results showed that the rate of thorium (IV) uptake under optimal conditions is 183.95 mg/g. The modeling results showed that the experimental data of thorium biosorption kinetics are fitted well by the pseudo-second-order model. According to the results, the biosorption process reached equilibrium after around 4 h of contact. The Langmuir isotherm describes the experimental biosorption equilibrium data well. The maximum absorption capacity of protonated orange peel for thorium adsorption was estimated by the Langmuir isotherm at 236.97 mg/g. Thermodynamic studies show that thorium adsorption on protonated orange peel is thermodynamically feasible, spontaneous, and endothermic.
Techno-economic assessment of battery storage with photovoltaics for maximum self-consumption
Authors: Hassan Qusay , Abbas Majid K. , Tabar Vahid Sohrabi , Tohidi Sajjad , Sameen Aws Zuhair , Salman Hayder M. 
Published: March 2023

Abstract
The study provided a techno-economic optimization technique for acquiring the ideal battery storage capacity in conjunction with a solar array capable of meeting the desired residential load with high levels of self-sufficiency. Moreover, the viability of a proposed photovoltaic battery system was evaluated. With a resolution of one minute, the annual energy consumption, irradiance, and ambient temperature for 2021 have been measured. Simulations of a stationary economic model are run from 2021 to 2030. Based on the experimental evaluation of the annual energy consumption, which was 3755.8 kWh, the study reveals that the photovoltaic array with a capacity of 2.7 kWp is capable of producing an annual energy production of 4295.5 kWh. The optimal battery capacity determined was 14.5 kWh, which can satisfy 90.2% of self-consumption at the cost of energy $0.25/kWh. Additionally, two third-order polynomial relationships between self-consumption and net present costs and energy cost were established.
Determinants of synergistic cell-cell interactions in bacteria
Authors: Pauli Benedikt , Ajmera Shiksha , Kost Christian 
Published: March 2023

Abstract
Bacteria are ubiquitous and colonize virtually every conceivable habitat on earth. To achieve this, bacteria require different metabolites and biochemical capabilities. Rather than trying to produce all of the needed materials by themselves, bacteria have evolved a range of synergistic interactions, in which they exchange different commodities with other members of their local community. While it is widely acknowledged that synergistic interactions are key to the ecology of both individual bacteria and entire microbial communities, the factors determining their establishment remain poorly understood. Here we provide a comprehensive overview over our current knowledge on the determinants of positive cell-cell interactions among bacteria. Taking a holistic approach, we review the literature on the molecular mechanisms bacteria use to transfer commodities between bacterial cells and discuss to which extent these mechanisms favour or constrain the successful establishment of synergistic cell-cell interactions. In addition, we analyse how these different processes affect the specificity among interaction partners. By drawing together evidence from different disciplines that study the focal question on different levels of organisation, this work not only summarizes the state of the art in this exciting field of research, but also identifies new avenues for future research.