bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effectiveness of Infrared and William Flexion Exercise on Reducing Pain and Increasing Flexibility in Patients with Low Back Pain
Authors: Halimah Nurul , Pradita Angria 
Published: August 2023

Introduction: The condition of low back pain is a musculoskeletal problem without age limit. Patients with lower back pain tend to take analgesic drugs to reduce pain. Apart from pharmacological consumption, the tendency for low back pain sufferers to seek other alternatives, namely; physiotherapy treatment. One of the physiotherapy treatments for low back pain is giving infrared and William flexion exercise or a combination of both. This study aims to determine the effectiveness of infrared and William flexion in reducing pain and flexibility of the lumbar muscles. Method: The research design is quasi experimental pre-posttest with control group. The study population consisted of 44 patients with low back pain at Physiomar Clinic by dividing 40 samples into intervention groups (William flexion exercise) and control group (Infrared and William Flexion Exercise) 2 times/week for 1 month. The pain level measured by using the Visual Analog Scale (VAS) and flexibility using the Modified Schober Test (MST). The data was analyzed by Wilcoxon and Mann Whitney (α≤0.05). Results: This study in intervention group showed a median pre-post pain score of 6.00-5.00 and a median pre-post flexibility value of 3.00-3.00 (p=0.000); while control group showed a median pre-post pain score of 6.00-2.00 and a median pre-post flexibility value of 2.50-10.00 (p=0.000). The combination of infrared and William flexion exercise is better than William flexion exercise for changes in pain and flexibility in low back pain patients at the physiomar clinic
Mechanische Zelldemontage für das direkte Recycling/Mechanical battery cell disassembly for direct end-of-life battery recycling
Authors: Henschel Sebastian , Dörner Philipp-Tobias , Kößler Florian , Fleischer Jürgen 
Published: August 2023

Die Ziele der Verkehrswende führen zu einem stetig steigenden Bedarf an Lithium-Ionen-Batterien. Damit diese am Ende ihres Lebenszyklus in einigen Jahren nicht als Abfall anfallen, sondern die darin enthaltenen wertvollen Rohstoffe weiter genutzt werden können, ist ein effektives Recycling im Sinne der Kreislaufwirtschaft notwendig. Hierzu wird in diesem Beitrag ein Konzept zur mechanischen Demontage von Batteriezellen als Grundstein für ein direktes Recycling vorgestellt.

The goals of the transportation revolution are leading to a steadily increasing demand for lithium-ion batteries. To prevent the valuable raw materials in these batteries from ending up as waste as soon as the batteries‘ life cycle ends in a few years and to ensure that these materials continue to be used, effective recycling in the sense of a circular economy is necessary. To this end, this paper presents an appraoch for mechanically disassembling battery cells as a cornerstone for direct recycling.
Digitale Transformation industrieller Services/Digital transformation of industrial services
Authors: Große Nick , Hefft Daniel , Wortmann Caroline , Eichholz Jonas , Kiklhorn David 
Published: August 2023

In Zeiten zunehmender Vernetzung und Digitalisierung stehen kleine und mittelständische Unternehmen vor der Herausforderung, neben den bisherigen Produkten digitale Zusatzleistungen anzubieten. Es fehlt vor allem an praxisnahen Leitfäden, die aufzeigen, wie sich diese digitale Transformation tatsächlich verwirklichen lässt. Dieser Beitrag vereint abgeleitete Erkenntnisse aus wissenschaftlicher Literatur sowie unternehmerischer Praxis und zeigt zwölf Handlungsempfehlungen zur digitalen Transformation industrieller Services auf.

In times of increasing networking and digitization, small and medium-sized enterprises face the challenge of offering additional digital services alongside their existing products. Above all, there is a lack of practical guidelines that show how this digital transformation can actually be realized. This contribution combines findings derived from scientific literature and business practice and gives twelve recommendations for action for the digital transformation of industrial services.
The Seven-parameter Diffusion Model: an Implementation in Stan for Bayesian Analyses
Authors: Henrich Franziska , Hartmann Raphael , Pratz Valentin , Voss Andreas , Klauer Karl Christoph 
Published: August 2023

AbstractDiffusion models have been widely used to obtain information about cognitive processes from the analysis of responses and response-time data in two-alternative forced-choice tasks. We present an implementation of the seven-parameter diffusion model, incorporating inter-trial variabilities in drift rate, non-decision time, and relative starting point, in the probabilistic programming language Stan. Stan is a free, open-source software that gives the user much flexibility in defining model properties such as the choice of priors and the model structure in a Bayesian framework. We explain the implementation of the new function and how it is used in Stan. We then evaluate its performance in a simulation study that addresses both parameter recovery and simulation-based calibration. The recovery study shows generally good recovery of the model parameters in line with previous findings. The simulation-based calibration study validates the Bayesian algorithm as implemented in Stan.
NuSTAR Observations of Four Mid-IR–Selected Dual AGN Candidates in Galaxy Mergers
Authors: Pfeifle Ryan W. , Weaver Kimberly , Satyapal Shobita , Ricci Claudio , Secrest Nathan J. , Gliozzi Mario , Blecha Laura , Rothberg Barry 
Published: August 2023

Abstract
Mergers of galaxies are a ubiquitous phenomenon in the universe and represent a natural consequence of the “bottom-up” mass accumulation and galaxy evolution cosmological paradigm. It is generally accepted that the peak of active galactic nucleus (AGN) accretion activity occurs at nuclear separations of ≲10 kpc for major mergers. Here we present new NuSTAR and XMM-Newton observations for a subsample of mid-IR preselected dual AGN candidates in an effort to better constrain the column densities along the line of sight (LOS) for each system. Only one dual AGN candidate, J0841+0101, is detected as a single, unresolved source in the XMM-Newton and NuSTAR imaging, while the remaining three dual AGN candidates, J0122+0100, J1221+1137, and J1306+0735, are not detected with NuSTAR; if these nondetections are due to obscuration alone, these systems are consistent with being absorbed by column densities of log(N
H/cm−2) ≥ 24.9, 24.6, and 24.3, which are roughly consistent with previously inferred column densities in these merging systems. In the case of J0841+0101, the analysis of the 0.3–30 keV spectra reveal an LOS column density of N
H ≳ 1024 cm−2, significantly larger than the column densities previously reported for this system and demonstrating the importance of the higher signal-to-noise ratio XMM-Newton spectra and access to the >10 keV energies via NuSTAR. Though it is unclear if J0841+0101 truly hosts a dual AGN, these results are in agreement with the high obscuring columns expected in AGNs in late-stage mergers.
Neutrino-driven Winds in Three-dimensional Core-collapse Supernova Simulations
Authors: Wang Tianshu , Burrows Adam 
Published: August 2023

Abstract
In this paper, we analyze the neutrino-driven winds that emerge in 12 unprecedentedly long-duration 3D core-collapse supernova simulations done using the code Fornax. The 12 models cover progenitors with zero-age main-sequence mass between 9 and 60 solar masses. In all our models, we see transonic outflows that are at least 2 times as fast as the surrounding ejecta and that originate generically from a proto−neutron star surface atmosphere that is turbulent and rotating. We find that winds are common features of 3D simulations, even if there is anisotropic early infall. We find that the basic dynamical properties of 3D winds behave qualitatively similarly to those inferred in the past using simpler 1D models, but that the shape of the emergent wind can be deformed, very aspherical, and channeled by its environment. The thermal properties of winds for less massive progenitors very approximately recapitulate the 1D stationary solutions, while for more massive progenitors they deviate significantly owing to aspherical accretion. The Y

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temporal evolution in winds is stochastic, and there can be some neutron-rich phases. Though no strong r-process is seen in any model, a weak r-process can be produced, and isotopes up to 90Zr are synthesized in some models. Finally, we find that there is at most a few percent of a solar mass in the integrated wind component, while the energy carried by the wind itself can be as much as 10%–20% of the total explosion energy.
NY Bootes: An Active Deep and Low-mass-ratio Contact Binary with a Cool Companion in a Hierarchical Triple System
Authors: Meng Fangbin , Zhu Liying , Qian Shengbang , Liu Nianping , Li Linjia , Matekov Azizbek 
Published: August 2023

Abstract
The first detailed photometric and spectroscopic study of G-type short-period binary NY Boo is presented. The radial velocity curve was obtained by the cross-correlation function (CCF) method based on LAMOST and SDSS spectra, which derived its mass ratio as q = 0.139(1/7.2). The CCF profiles of the SDSS spectra clearly show the existence of a cool third component, which is supported by the results of the orbital period investigation. The period study based on the O-C analysis indicates that besides a long-term decrease, the orbital period has a periodic oscillation due to the light-travel time effect caused by a third body. When the third light contribution is consistent with the CCF results, the orbit of the third body and the inner pair are non-coplanar with m
3 = 0.31 M
⊙. Combining with the TESS light curves, it is found that the target is a deep and low-mass-ratio contact binary (DLMRCB) with a fill-out factor of f = 73%. The notable asymmetry in light curves was detected and explained by the spot model very well. The spectroscopic profiles, the cyclic variation in the O-C diagram, and the radial velocity curve and light-curve solutions all suggest that NY Boo is a hierarchical triple system with a cool tertiary component orbiting around an active DLMRCB. With the orbital period shrinking, the binary may eventually merge. The period of NY Boo decreases faster than other shrinking DLMRCB, together with active inner pair and non-coplanar tertiary component, making NY Boo an important target for studying the late evolution of binaries.
The Case for Future Gravity Science Investigations at Saturn with a Planetary Orbiter
Authors: Parisi Marzia 
Published: August 2023

Abstract
The next phase in the robotic exploration of the Saturnian system will target unresolved questions about the gas giant’s atmosphere, interior, magnetosphere, and rings that were left open by investigations on board the Cassini mission. Among these, we find gravity science objectives, which relate mainly to explaining the origin of the large wind-induced gravity signal and reconciling existing incongruities regarding the internal density distribution. Here we attempt to identify which future observations may yield additional information about Saturn’s internal mechanisms. We report on the results of precise numerical simulations of a gravity science experiment carried out with a planetary orbiter in the 2040s and characterized by varying periapsis altitude over the 1 bar planetary surface. The goal is to identify achievable measurement requirements that can advance the current understanding of Saturn’s interior and atmospheric dynamics. We find that inclined, elliptical orbits with low-altitude closest approaches over the northern hemisphere can improve the present determination of the gravity field coefficients by up to 1 order of magnitude, provided that at least a dozen pericenters are devoted to gravity science. Furthermore, if future observations are combined with the available Cassini Grand Finale data in the southern hemisphere, a significant improvement in terms of maximum measurable gravity field degree is observed.
Diagnostic accuracy of cone-beam computed tomography with modified grayscale range for detection of buccal cortical plate defects adjacent to dental implants
Authors: Yaghoobi Soophia , Kajan Zahra Dalili , Khosravifard Negar , Sigaroudi Ali Khalighi , Jouybari Reza Modanlou 
Published: August 2023

Background:
This study assessed the diagnostic accuracy of cone-beam computed tomography (CBCT) with a modified grayscale range for the detection of buccal cortical plate defects adjacent to dental implants.

Materials and Methods:
In this in vitro experimental study, titanium implants were inserted in 168 fresh bovine bone blocks with 1–1.5 mm of buccal cortical plate thickness. The blocks were randomly divided into four groups (n = 42). No defect was created in the control blocks. In the three experimental groups, cortical plate defects were randomly created in the cervical, middle, or apical third by a round bur with a 2-mm diameter (n = 42). All blocks underwent CBCT with and without change in the grayscale range. Two observers evaluated all images regarding the presence/absence of defects. Kappa test is used for the agreement of the observers. The diagnostic accuracy of the two modalities was compared by calculating the area under the receiver operating characteristic curve (AUC) (P ≤ 0.05). The sensitivity and specificity values were also compared.

Results:
The AUC was not significantly different between the two modalities with and without altered grayscale range (0.754 vs. 0.762, respectively, P = 0.716). The diagnostic sensitivity of CBCT with and without change in the grayscale range was 51% and 52%, respectively, with a specificity of 100% for both. The diagnostic accuracy of CBCT with and without altered grayscale range had no significant difference for apical and middle third defects (P > 0.05) and was significantly higher than that for the cervical third defects (P < 0.05).

Conclusion:
Changing the grayscale range does not improve the diagnostic accuracy of CBCT for the detection of buccal cortical plate defects adjacent to dental implants.
Effect of bioactive glass-containing dentin adhesives on microshear bond strength of composite restorations
Authors: Mousavinasab Sayed Mostafa , Sarandi Farzad , Rezvanian Parsa , Atai Mohammad , Mousavinasab Sepidehsadat 
Published: August 2023

Background:
In general, bioactive glasses (BAGs) can react with tissue minerals and promote remineralization. However, the application of BAG in bonding agents and its impact on bond strength remain uncertain due to insufficient information and limited research in this area.

Materials and Methods:
This study employed a randomized controlled design to assess the effects of composite-bonding agents with varying BAG contents on shear bond strength and fracture pattern in sound and demineralized teeth, with and without thermocycling. Thus, 80 healthy third molars were randomly divided into two groups: sound teeth and demineralized teeth. Five bonding agents were applied to the prepared dentin surfaces, including four experimental composite-bonding agents with varying BAG content (0, 0.2, 0.5, and 2 wt%) and the Adper Single Bond commercial bonding as control. The shear bond strength of all samples was measured using a universal tester. The type of failure of each specimen was determined using a stereomicroscope. Kruskal–Wallis nonparametric test was performed on the obtained shear bond strength data followed by Mann–Whitney post hoc test with Bonferroni correction to determine statistical significance. The level of significance was considered P ≤ 0.05 for all tests and was adjusted by Bonferroni correction.

Results:
Demineralization significantly decreased shear bond strength in the teeth samples. Adper Single Bond exhibited the highest shear bond strength values. The addition of BAG did not have a significant influence on shear bond strength, regardless of demineralization or thermocycling condition. Adhesive failure was the predominant type of failure in all groups.

Conclusion:
The incorporation of BAG filler up to 2 wt% did not result in significant changes in shear bond strength. Experimental adhesive bonding agents with 2 wt% BAG content demonstrated shear bond strengths comparable to the commercial bonding agent in sound nontreated, sound thermocycled, demineralized nontreated, and demineralized thermocycled groups.
The impact of chemotherapy on quality of life in advanced-stage lung cancer patients
Authors: Fernandes Sharon S. , Saini J. K. 
Published: August 2023

Abstract

Background:
Most patients with lung cancer are diagnosed at advanced stages of the disease, where chemotherapy plays an important role. This prospective study was conducted to determine the impact of palliative chemotherapy on quality of life (QOL) in advanced-stage lung cancer patients.

Methods:
QOL in lung cancer out-patients was assessed at diagnosis and end of treatment using the EORTC QLQ-C30 questionnaire. Changes in mean QOL scores were calculated. The correlation between patients’ tumor response and change in QOL scores was also studied. Scoring was done according to the EORTC manual and results were analyzed using SPSS statistical package.

Results:
Out of 52 patients, 46 (88.46%) were men and six (11.54%) were women. After chemotherapy, patients’ overall QOL score improved significantly (P = 0.005). Cognitive functioning significantly worsened (P = 0.01). Physical functioning (PF) and emotional functioning (EF) scores improved, while role functioning (RF) and social functioning (SF) scores worsened. Pain, dyspnea, and sleep significantly improved (P = 0.001, P = 0.001, and P = 0.005 respectively). On the other hand, nausea, vomiting (P = 0.000), diarrhea (P = 0.004), and financial difficulties (P = 0.009) worsened. Overall QOL improved in patients with partial tumor response (PR) and stable disease (SD) (P = 0.044 and P = 0.000, respectively), but worsened in progressive disease group (PD) (P = 0.648). Symptom scores improved markedly in PR and SD groups. Chemotherapy toxicity was maximum in PD group (P = 0.028).

Conclusion:
Global quality of life and symptom control significantly improved in lung cancer patients after chemotherapy. Deterioration of cognitive functioning, increased financial burden, and chemotherapy-related toxicity were noteworthy. Changes in QOL were coherent with patients’ tumor response.
Transvaginal natural orifice specimen extraction surgery for 3D laparoscopic radical cystectomy: A cohort study
Authors: Wu Liyuan , Zhao Qinxin , Yang Feiya , Wang Mingshuai , Xing Nianzeng 
Published: August 2023

ABSTRACT

Objective:
Transvaginal natural orifice specimen extraction surgery (NOSES) has been widely used in laparoscopic surgery due to its benefits. However, laparoscopic radical cystectomy (LRC) with NOSES has rarely been reported.

Materials and Methods:
A retrospective analysis of 25 patients who underwent 3D LRC with NOSES from November 2014 to November 2019 was performed. The clinical and perioperative related data, peri and postoperative complications, and oncologic outcomes were recorded.

Results:
Surgery was successfully completed in 25 patients, and none were converted to open surgery. Mean total operative time was 294.1 ± 48.80 min. Mean NOSES time was12 ± 6.48 min. The median post-op hospital stay was 10.5 d (range 6-27 d). The median visual analog pain score on post-op day 1, 2, and 3 was 2, 2, and 1, respectively. Thirteen patients had 30-day complications (3 had Clavien grade I and 11 had Clavien grade II). Pelvic floor distress inventory-short form 20 (PFDI-20) was 9.8 ± 1.9 after three months (compared with pre-PFDI-20, P = 0.06) and 9.3 ± 1.2 after six months (compared with pre-PFDI-20, P = 0.15). At the mean follow-up of 24.7 ± 12.05 months (range 11-60 months), one patient (4%) had recurrence, two (8%) had metastasis, and one (4%) died.

Conclusion:
Transvaginal NOSES in 3D LRC is safe and feasible. Understanding the female vagina anatomy and comprehending the techniques is conducive to avoid incision-related complications. NOSES is minimally invasive with good cosmetic outcomes with few surgical complications or affecting pelvic floor function.
Significant response to transarterial chemoembolization combined with PD-1 inhibitor and apatinib for advanced intrahepatic cholangiocarcinoma: A case report and literature review
Authors: Zhang Haitao , Han Cuiping , Zheng Xiaohuan , Zhao Wenhua , Liu Yuanshui , Ye Xin 
Published: August 2023

ABSTRACT
Intrahepatic cholangiocarcinoma (ICC) is a highly aggressive malignancy rising from the biliary tree with poor prognosis. We report the feasibility and efficacy of transarterial chemoembolization (TACE) combined with PD-1 inhibitor and apatinib for the treatment of a patient with unresectable ICC. A 70-year-old female presented with intermittent right upper abdominal distension, abdominal pain, and vomiting after eating for more than one month. Enhanced computed tomography (CT) and magnetic resonance imaging (MRI) scan revealed multiple intrahepatic lesions, retroperitoneal lymph node, and left lung metastasis. Based on the patient’s medical history and pathology, the diagnosis was confirmed as locally advanced unresectable ICC. Multimodal therapy was applied to the ICC. The therapy comprised TACE every three months, and a combination regimen of the PD-1 inhibitor camrelizumab and the antiangiogenic agent apatinib. The patient underwent microwave ablation for a lesion on the left lung that had not responded to systemic therapies. Enhanced CT scan after every 2–3 months was performed. After several sessions, the primary lesion reduced dramatically in size. At 20 months from diagnosis, the patient was alive, in good condition, and stable. The patient experienced no critical complications and toxicity associated with the administered therapies. This case suggests that treatment with TACE combined with systemic therapy of camrelizumab combined with apatinib may be a safe and effective treatment option for patients with inoperable ICC.
Clinical features and outcomes of infantile soft-tissue sarcoma: A multicenter retrospective study in Beijing
Authors: Zhu Shuai , Xu Na , Zhi Tian , Gao Yangxu , Zhong Dixiao , Zhang Weiling , Jin Mei , Sun Qing , Xie Yao , Zhang Xiaolun , Li Long , Wang Shengcai , Wang Huanmin , Liu Rong , Zhao Weihong , Huang Dongsheng , Ni Xin , Ma Xiaoli 
Published: August 2023

ABSTRACT

Background:
Soft-tissue sarcomas during infancy are rare and understudied. With no data on this specific condition, we performed a retrospective study of infant-onset sarcomas based on a multi-institutional cohort in Beijing, China, collected over the past decade. We reviewed infantile soft-tissue sarcomas’ clinical characteristics, treatments, and outcomes.

Materials and Methods:
The patients with soft-tissue sarcoma diagnosed from 0 to 12 months in four primary children’s hospitals in Beijing from January 2010 to December 2019 were evaluated.

Results:
Fifty-one patients were enrolled, including 31 males and 20 females. The median age at the diagnosis was five months (range, 0-12), and seven (13.7%) patients were diagnosed in the first month of their life. Histologically, twenty-five patients were diagnosed with rhabdomyosarcoma (RMS), six were diagnosed with extraosseous Ewing sarcoma (EES), and twenty were diagnosed with nonrhabdomyosarcoma soft-tissue sarcoma (NRSTS). The treatment principles and details of RMS focused on reference to the Intergroup Rhabdomyosarcoma Study Group (IRSG) protocols. For EES and NRSTS, chemotherapy was prescribed according to children’s oncology group protocols. The five-year EFS/OS rates of RMS were 26.4% ± 19.5%/56.2 ± 17.8%, the five-year EFS/OS rate of EES was 50% ± 20.4%, and the five-year EFS/OS of NRSTS was 85.2% ± 9.8%/100%.

Conclusions:
Infant-onset soft-tissue sarcoma is heterogeneous. The primary location of the abdominal or pelvic cavity of RMS and EWS was at a later stage and had a poorer prognosis. Multimodal therapy resulted in successful disease control for the majority of patients. Standardization of treatment protocols will facilitate care for such challenging conditions.