bluuebunny/crossref_metadata_2025_split huggingface dataset:
Profil Aspek Interpretasi Pemahaman Konsep Materi Kinematika Gerak Lurus pada Siswa SMAN 6 Kota Bengkulu
Authors: Apridonata Wahyu , Syarkowi Ahmad , Purwanto Andik 
Published: March 2023

Penelitian ini bertujuan untuk menganalisis gambaran mengenai pemahaman konsep pada materi kinematika gerak lurus pada aspek interpretasi. Metode penelitian yang digunakan yakni menggunakan metode cross sectional. Sampel pada penelitian ini yakni siswa SMAN 6 Kota Bengkulu sebanyak 70 responden. Berdasarkan hasil yang diperoleh siswa SMAN 6 Kota Bengkulu dikategorikan sedang dalam menjawab soal pemahaman konsep aspek interpretasi khususnya pada materi kinematika gerak lurus dengan persentase rata-rata skornya 35,12%. Instrumen yang digunakan berupa soal pretest pilihan ganda dimana satu soal memiliki lima pilihan jawaban. Berdasarkan hasil test responden terdapat indikator yang ketiga yaitu menjelaskan ciri-ciri gerak jatuh bebas memiliki persentase tertinggi sebesar 45% dan indikator pertama yakni menjelaskan perbedaan gerak lurus dengan kecepatan konstan dan gerak lurus dengan percepatan konstan memiliki persentase terendah sebesar 30%. Sehingga pemahaman konsep pada siswa SMAN 6 Kota Bengkulu masih dikategorikan sedang. This study aims to analyze the understanding of straight motion kinematics in interpretation. The research method used is a cross-sectional method. This study's sample was SMAN 6 Bengkulu City students, with as many as 70 respondents. Based on the results obtained by students of SMAN 6 Bengkulu City, they are categorized as moderate in answering questions about understanding the concept of interpretation aspects, especially in straight-motion kinematics material, with an average percentage score of 35.12%. The instrument used is in the form of multiple choice pretest questions where one question has five answer choices. Based on the results of the respondent's test, there is a third indicator, namely explaining the characteristics of free fall motion, which has the highest percentage of 45% and the first indicator, which explains the difference between straight motion with constant speed and straight motion with constant acceleration, has the lowest percentage of 30%. So that the understanding of the concept in SMAN 6 Bengkulu City students is still categorized as moderate.
Pengembangan Instrumen Tes Keterampilan Problem Solving pada Materi Gerak Lurus di SMA
Authors: Patimah Siti , Putri Desy Hanisa , Syarkowi Ahmad 
Published: March 2023

Penelitian ini bertujuan untuk menghasilkan instrument tes keterampilan problem solving yang valid dan mengetahui kelayakan instrumen tes keterampilan problem solving pada materi gerak lurus. Penelitian ini menggunkan model (Research andDevelopment). Dalam penelitian ini menggunakan model 4D denganlangkah-langkahDefine,Design,Develop dan Dissemination. Namun untuk penelitian ini dibatasi sampai tahap 3D yaitu Define,Design, dan Develop. Tahapan analisis pada Define dilakukan dengan penyebaran angket kebutuhan yang dilakukan di tiga sekolah yaitu SMA N 7 Kota Bengkulu, SMA N 4 Kota Bengkulu, dan SMA N 9 Kota Bengkulu kemudian dilakukan perancangan pengembangan instrument soal. Instrumen tes berisikan 6 soal uraian yang menggunakan indikator keterampilan problem solving. Setelah itu instrument yang telah disusun divalidasi oleh tiga pakar yaitu dua ahli dan satu praktisi. Berdasarkanhasilujivalidasiaspekmateri, aspek konstruksi, aspek bahasa memperoleh persentase validasi berturut-turut sebesar 100%, 98,6% dan 100%. Dengan demikian instrumen yang disusun dikategorikansangat layak digunakan. This study aims to produce a valid problem-solving skill test instrument and determine the feasibility of a problem-solving skill test instrument on straight-motion material.This research uses a model (Research and Development). The development model used is a 4D model with the steps of Define, Design, Develop and Dissemination. However, this research is limited to the 3D stage, namely Define, Design, and Develop. The analysis stage in Define was carried out by distributing a needs questionnaire which was carried out in three schools, namely SMA N 7 Bengkulu City, SMA N 4 Bengkulu City, and SMA N 9 Bengkulu City; then carried out the design of the question instrument development. The test instrument contains six description questions that use problem-solving. After that, the instrument that has been compiled is validated by three experts, namely two experts and one practitioner. Based on the validation test results, the material aspect, construction aspect, and language aspect obtained validation percentages of 100%, 98.6% and 100%, respectively. Thus, the instruments compiled are categorized as very suitable for use.
OBJECTIVES AND INFORMATION BASE FOR ANALYZING THE EFFICIENCY OF LABOR RESOURCES UTILIZATION
Authors: Pohorielov Serhiy 
Published: March 2023

The development of market relations and related structural changes in the economy have a significant impact on the processes of economic activity. Most enterprises operate in a tough environment of external and internal competition, which requires them to take active steps to optimize and adjust technological processes and economic strategy, both current operations and enterprise development. Optimization and adjustment of current operations is achieved by making appropriate management decisions, which requires a comprehensive analysis of the company's performance. It is used to develop the strategy and tactics of the company's development, to make plans and management decisions, to monitor their implementation, to identify reserves for improving production efficiency, and to evaluate the performance of the company, its divisions and employees.
At the same time, as the practice of Ukrainian enterprises, especially privatized ones, shows, the use of modern methods is too limited, as evidenced by the large number of economically inexpedient business projects at various levels, low levels of labor productivity and profitability, unreasonably high costs of maintaining the administrative apparatus, which ultimately leads to severe financial losses up to the bankruptcy of the enterprise.
Undoubtedly, this situation is shaped by a number of factors, among which the economic instability of the external business environment is the most important. However, internal factors also play a significant role, namely, the low level and quality of enterprise management, one of which is the inability to analyze activities and identify factors affecting both economic activity and the financial position of an enterprise.
Maintaining Structural Integrity for New Well Design
Authors: Khan Danish Ahmed , Acuna Manuel Centeno , Al-Asadi Yousif Baqer , Sebbane Slimane , Tossonian Hoory , Chica Pablo , Hussein Ahmed Mudheher 
Published: March 2023

Abstract
Maintaining the structural integrity of the wellbore and preventing it from collapsing requires maintaining the balance between in-situ stresses and drilling practices. Historically, deviated wells drilled in this super-giant oil field in Iraq (Figure 1 – Iraq Field developments), with an estimated 38 billion barrels of oil in place in multiple reservoirs, were conservative and based on conventional well design. The conventional design approach separated Anhydrite-Marl and Gravel formations from the potential loss circulation zone of the porous vuggy limestone formations. The new well design, called the Slim Design, was to drill through these heterogeneous formations and isolate them across a single production casing with a significant reduction in well delivery time and tubular cost.
Construction of 1D Geomechanics Model is presented that uses data from offset open hole logs, offset well data, and utilizes mohr coulomb and modified lade methods to examine the wellbore stability models. These models were used to define the minimum required mud weight required to drill through heterogenous formations and avoid wellbore instability issues. Drilling strategy through loss zone was optimized based on risk identification from geomechanics – maintain Hydrostatic over Anhydrite-Marl and Gravel formations to prevent it from collapse. Severe to complete losses observed while performing 9-5/8in cement job due to natural fractures in Limestone formations can only be compensated by performing the top job i.e., the volume of cement required to fill the annulus to achieve the acceptance criteria. The cementing strategy was modified based on input from geo-mechanics as 90% of overburden vertical stress was used as a pressure limit to squeeze cement into the annulus. Results obtained from this study were in good agreement with field observations.
Figure 1 IRAQ FIELD DEVELOPMENTS1
High Power Laser Technology Toward the Downhole Applications: The Effect on Permeability
Authors: Alharith Abdullah , Batarseh Sameeh , San Roman Alerigi Damian 
Published: March 2023

Abstract
In response to the high oil and gas demand, new sustainable technologies were developed and evolved to improve the production. Among those new technologies is the high power laser technology. Laser technology attracted the industry due to its unique properties and the potential to revolutionize the oil and gas industry in many applications. Such applications include; drilling, perforation, descaling, pipe cutting, casing-casing annulus remedy, and fracture initiation.
This paper will discuss the effect of high power laser operations on the permeability during the utilization of this method for oil and gas applications. The interaction between the high power laser and the formation induces high thermal energy to the geological structure of the reservoir that will influence the permeability of the formation.
Different types of experimental work examine the consequences of high power laser on permeability. Several research studies are conducted on different rock samples; the samples include carbonate, sandstone, and shale. The high power laser induces thermal energy, which affects the physical structure of the rock sample by altering the physical and chemical properties of the rock. Such changes include decomposition reaction, dehydration, clays collapse, and micro-cracking. Various lab techniques are used for analysis and characterization, including thermogravimetric analyzer (TGA), and permeability measuring machine. The lab work showed improvement in permeability in most rock samples that are treated with high power laser energy. High power laser technology is a friendly environmental method for downhole oil and gas applications. The paper demonstrated that the technology is non-damaging and enhances the flow properties in the well. Improving the production by enhancing the permeability.
Audience Effects in Sooty Mangabey Agonistic Behaviour
Authors: Quintero Fredy , Touitou Sonia , Magris Martina , Zuberbühler Klaus 
Published: March 2023

Abstract
Aggression is a functional term that refers to behaviour in competitive interactions, such as repelling predators, accessing resources or pursuing other self-serving interests. However, aggression also has a secondary function as a partner control mechanism to extort cooperation and tolerance from others. Both functions are mainly available to high-ranking individuals interacting with lower-ranking opponents, which raises the question of how do lower-ranking individuals achieve their goals? One possibility is by predicting future reactions of uninvolved bystanders and adjusting one’s behaviour accordingly. Here, we investigated how free-ranging sooty mangabeys, a socially tolerant forest dwelling primate, used aggression depending on audience composition. As predicted, high-ranking individuals used aggression universally to displace lower-ranking competitors, but we also found several audience effects for other group members. First, aggression of lower-ranking individuals was significantly augmented in front of high-ranking audiences, often accompanied by vocalisations. Second, individuals generally refrained from severe aggression in front of friends and when audience size was small. We discuss these patterns of audience-dependent aggressive behaviour and conclude that, while mangabeys naturally pursue selfish goals, they also adjust levels and rates of aggression depending on who observes them, consistent with the idea of pursuing longer-term goals of securing cooperation and tolerance.
Key factors for teaching and learning - Teachers’ experiences and reflections on literacy teaching
Authors: Tjernberg Catharina Cecilia 
Published: March 2023

Abstract
A group of students were followed in a longitudinal study throughout their compulsory
school years. The data collected formed the starting point for a focusgroup
discussion, the results of which are reported and discussed in this article.
The aim is to investigate the factors that the teachers consider especially important
for the students’ learning processes, and to reflect on what characterises
teaching practices that promote participation and learning. The results show that
the most important factor in a successful teacher’s work is the ability to meet the
students according to their individual needs; this also involves using the student
group as a learning resource, and to adopt a critical attitude to one’s own teaching
with the aim of developing it. Attitude, high expectations and a positive belief in
the students are key factors here, as well as the ability to stage well-balanced
teaching with a focus on content, language, and language use.
The importance of collegial learning for the teacher’s professional development
is emphasised, as is the value of enjoying one’s work and to share both successful
and less successful pedagogical episodes. One surprising result is the teachers’
conscious efforts to help the students adopt strategies for learning.
Temozolomide Combined with Radiotherapy Can Benefit Patients with Glioma: A Systematic Review and Meta-Analysis
Authors: huang Qinhong , Yang Lihui , Ye Zhenwei , Yang Jing , Ke Yiquan 
Published: March 2023

Abstract
Background: Glioma originates from glial cells of the nervous system and is the most common malignant tumor in the brain. Temozolomide is considered as a promising medicine that can improve the overall survival (OS) and progress-free survival (PFS) rate of patients with glioma after operation. However, whether radiotherapy plus temozolomide has substantive role for glioma patients remains controversial.
Methods:We conducted a meta-analysis included 10 Randomized controlled trials (RCTs) encompassing 2703 patients to evaluate the efficacy and safety of radiotherapy plus temozolomide for glioma. EMbase, PubMed, Web of Science, and Cochrane library were searched. Our study strictly follows the PRISMA guideline.
Results:Overall, compared with receiving radiotherapy alone, patients through radiotherapy combined with temozolomide has substantial benefit on both OS (HR=0.78; 95% CI: 0.62-0.98; P =0.03) and PFS (HR=0.62; 95% CI: 0.49-0.78; P <0.0001). The best effect shows in patients receiving radiotherapy combined with both concurrent and adjuvant temozolomide on both OS (HR=0.66; 95% CI: 0.58-0.74; P <0.00001) and PFS (HR=0.55; 95% CI: 0.48-0.62; P <0.00001), when compared with radiotherapy alone. Whereas, temozolomide monotherapy do not show greater benefits than radiotherapy alone on OS (HR=0.93; 95% CI: 0.74-1.14; P =0.53). Moreover, radiotherapy plus temozolomide obviously increase the incidence of hematological complications than only radiotherapy (RR=10.31; 95% CI: 4.49-23.71; P<0.00001). Also, our meta-analysis suggested that MGMT methylation test can be helpful for evaluating prognosis, determining individualized treatment and forecasting the curative effect.
Conclusion:Radiotherapy combined with temozolomide, especially combined with both concurrent and adjuvant temozolomide has great benefit on both OS and PFS of glioma patients. Conditionally, patients with glioma receiving glioma MGMT methylation test have advantage over evaluating prognosis, determining individualized treatment and forecasting the curative effect. Last but not least, monitoring blood routine and remedying the possible abnormalities in time is especially necessary of patient receiving temozolomide therapy.
Contextualizing the Revised Patient Perception of Patient-Centeredness (PPPC-R) Scale in Primary Healthcare settings: a Validity and Reliability Evaluation Study
Authors: Cai Yiyuan , Guo Pengfei , Tu Jiong , Hu Mengyao , Liu Lingrui , Ryan Bridget L. , Liao Jing , Dev Rubee , Li Yiran , Huang Tianyu , Wang Ruilin , Li Kuang , Huang Ruonan , Li Xinfang , Melipillán Edmundo Roberto , Zhao Shuaixiang , He Wenjun , Wang Xiaohui , Zhang Nan , Xu Dong（Roman） 
Published: March 2023

Abstract
Background The Patient Perception of Patient-Centeredness (PPPC) scale in English was recently revised, and it is necessary to test this instrument in different primary care populations.
Aim This study aimed to assess the validity and reliability of a Chinese version of the PPPC scale.
Design Delphi method was used to address the content validity of the PPPC scale by calculating the Content Validity Index, Content Validity Ratio, the adjusted Kappa, and the Item Impact Score. Confirmatory factor analysis (CFA) and exploratory factor analysis (EFA) were used to assess the construct validity of the PPPC scale. The internal consistency was also assessed.
Setting/participants A cross-sectional survey included 188 outpatients in Guangzhou city and 108 outpatients in Hohhot city from community health service centers or stations.
Results The 21 items in the scale were relevant to the component they belong to. The Item-level Content Validity Index for each item was higher than 0.79, and the average Scale-level content validity index was 0.97 in each evaluation round. The initial proposed 4-factor CFA model did not fit adequately. Still, we found a 3-factor solution based on our EFA model and the validation via the CFA model (model fit:χ2=294.573, P<0.001, RMSEA=0.044, CFI=0.981; factor loadings: 0.553 to 0.888). Cronbach's α also indicated good internal consistency reliability: The overall Cronbach's α was 0.922, and the Cronbach's α for each factor was 0.851, 0.872, and 0.717, respectively.
Conclusions The Chinese version of the PPPC scale provides a valuable tool for evaluating patient-centered medical service quality.
Determination of Online Thin Film Buckling Configuration by Parametric Optimization for Flexible Sensor Application
Authors: Kim Yeoun-Jae , Wi Daehan , Kim Jingyu , Choi Jaesoon 
Published: March 2023

Abstract
The thin film flexible sensor has applications in the medical field in measuring the electro cardiography (ECG) signals to localize and quantize the physiological condition/status of heart. Owing to the flexible nature of the thin film, its configuration changes with respect to the contact boundary condition when it comes in contact with the target surface. Therefore, to accurately localize the flexible sensor, the thin film flexible sensor's configuration must be determined accurately in an on-line fashion. As a study of localizing the thin film flexible sensor, this study proposes an on-line thin film buckling configuration determination method using parametric optimization and interpolation technique. With the specific modulus of elasticity and dimensions of the thin film flexible sensor of the mapping catheter prototype, the buckling configuration with two point boundary condition under axial load can be calculated online with approximately 0.1 mm absolute ya value error compared with that of the experiment. The result of the proposed method is also compared with that of the numerical simulation by ANSYS, which has approximately 0.4 mm absolute ya value error compared with that of the experiment.
Rapid detection of goose astrovirus genotypes 2 using real-timereverse transcription recombinase polymerase amplification
Authors: Li Haiqin , Zhu Yujun , Wan Chunhe , Wang Zhangzhang , Liu Lei , Tan Meifang , Zhang Fanfan , Zeng Yanbing , Huang Jiangnan , Wu Chengcheng , Huang Yu , Kang Zhaofeng , Guo Xiaoqiao 
Published: March 2023

Abstract
Background
Goose astrovirus (GoAstV) is an important pathogen that causes joint and visceral gout in goslings. It has been circulating in many provinces of China since 2017. Goose astrovirus genotypes 2 (GoAstV-2) is the main epidemic strain, and its high morbidity and mortality have caused huge economic losses to the goose industry. An accurate point-of-care detection for GoAstV-2 is of great significance. In this study, we developed a real-time reverse transcription recombinase polymerase amplification (RT-RPA) method for the on-site detection of GoAstV-2 infection.
Results
The real-time RT-RPA reaction was carried out at a constant temperature of 39°C, and the entire detection time from nucleic acid preparation to the end of amplification was only 25 min using the portable device. The results of a specificity analysis showed that no cross-reaction was observed with other related pathogens. The detection limit of the assay was 100 RNA copies/µL. The low coefficient of variation value indicated excellent repeatability. We used 270 clinical samples to evaluate the performance of our established method, the positive concordance rates with RT-qPCR were 99.6%, and the linear regression analysis revealed a strong correlation.
Conclusions
The established real-time RT-RPA assay showed high rapidity, specificity and sensitivity, which can be widely applied in the laboratory, field and especially in the resource-limited settings for GoAstV-2 point-of-care diagnosis.
Faecalibacterium duncaniae A2-165 regulates the expression of butyrate synthesis, ferrous iron uptake, and stress-response genes based on acetate consumption
Authors: Verstraeten Sophie , Layec Séverine , Auger Sandrine , Juste Catherine , Henry Céline , Charif Sawiya , Jaszczyszyn Yan , Sokol Harry , Beney Laurent , Langella Philippe , Thomas Muriel , Huillet Eugénie 
Published: March 2023

Abstract
The promising next-generation probiotic Faecalibacterium
prausnitzii is one of the most abundant acetate-consuming,
butyrate-producing bacteria in the healthy human gut. Yet, little
is known about how acetate availability affects this bacterium’s
gene expression strategies. Here, we show that, in the early
stationary phase, F. duncaniae strain A2-165 (previously
known as F. prausnitzii) can strongly regulate the
expression of metabolic and stress-response genes based on acetate
availability. Using RNA-seq, we compared gene expression patterns
between two growth phases (late exponential vs. early stationary)
and two acetate levels (low: 3 mM vs. high: 23 mM). Remarkably,
transcription levels were high for the gene encoding the MAM
protein, a pattern that was unaffected by acetate levels. At
low-acetate levels, a general stress response was activated, and
protein synthesis expression was down-regulated. At high- acetate
levels, there was greater expression of genes related to butyrate
synthesis and to the importation of B vitamins and iron.
Specifically, expression was strongly activated in the case of the
feoAABC operon, which encodes a FeoB ferrous iron
transporter, but not in the case of the feoABgene, which
encodes a second FeoB transporter. RT-PCR revealed that excess
ferrous iron repressed feoB gene expression. Finally, we
detected FeoB peptides from strain A2-165 in a healthy human fecal
metaproteome. In conclusion, we characterized two early stationary
lifestyles for F. duncaniae A2-165 that relate to acetate
consumption. Through multiomics and targeted approaches, this work
highlights the crucial role that the feoAABCoperon might
play in iron homeostasis in acetate-rich environments.