bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anomaly detection and facilitation AI to empower decentralized autonomous organizations for secure crypto-asset transactions
Authors: Ikeda Yuichi , Hadfi Rafik , Ito Takayuki , Fujihara Akihiro 
Published: January 2025

AbstractThis proposal introduces a novel decision-making framework to advance safe economic activities in cyberspace. We focus on identifying anomalies within crypto-asset trading, recognized as potential sources of criminal activity, severely undermining the credibility of such assets. Detecting and mitigating such anomalies holds significant societal implications, particularly in fostering trust within blockchain networks. We aim to bolster the “social trust” inherent to blockchain technology by facilitating informed economic activities in cyberspace. To achieve this, we propose integrating two artificial intelligence (AI) systems into a blockchain-based decentralized autonomous organization (DAO). The first AI application involves amalgamating various anomaly indicators, spanning from cluster coefficient, entropy, triangular motif analysis, correlation tensor analysis, loop component by Hodge decomposition, loop causality detection, network classification using graph Laplacian, and persistent homology analysis, into a comprehensive indicator using a Boltzmann machine. The second AI application entails deploying conversational AI to guide and support traders, aiding them in making informed trading decisions. This system is designed to alert DAO members to anomalies based on the integrated indicators, especially during massive price fluctuations. We operate under the assumption of close collaboration between governments, experts, traders, system developers, and operators to effectively organize DAOs. The primary technical challenge in our proposal lies in developing a wallet assisted by an intelligent software agent capable of safe interactions with traders within a unified DAO. With this organization, we envision fostering a global economic ecosystem where physical and cyber worlds converge, allowing democratic economic participation.
Moderating factors in psilocybin-assisted treatment affecting mood and personality: A naturalistic, open-label investigation
Authors: Irrmischer Mona , Puxty Drew , Yıldırım Barış Onur , Deijen Jan Berend , Engelbregt Hessel 
Published: January 2025

Abstract
Rationale
Psychedelic-assisted therapy is increasingly applied within mental health treatment.

Objectives
This study focused on factors moderating changes in the acute and long-term effects of an individual psilocybin-assisted program on depression, anxiety, PTSD and personality structures by including demographic factors, subjective experience and degree of mystical type experiences during the dosing, as well as emotional breakthrough and personal growth after the program.

Methods
At baseline, 1 week and 3 months after the psilocybin program participants completed the Generalized Anxiety Disorder Assessment (GAD-7), Patient Health Questionnaire (PHQ-9), PTSD Checklist for DSM-5 (PCL-5) and NEO Five-Factor Inventory-3 (NEO-FFI-3). In addition, after the dosing the Mystical Experiences Questionnaire (MEQ-30), Posttraumatic Growth Inventory (PTGI) and Emotional Breakthrough Inventory (EBI) were administered. Moderation effects were established using linear mixed-model analysis.

Results
A single high dose of psilocybin in combination with therapy was found to lower symptoms of anxiety, depression, PTSD and neuroticism over a period of 3-months. Scores on openness and conscientiousness increased after the treatment only. Participants reported mystical type experiences, emotional breakthrough and personal growth. These subjective experiences together with demographic factors were moderating the observed positive changes.

Conclusions
Findings indicate that individual psilocybin-assisted therapy has the potential for beneficial effects on mood and personality characteristics. Moreover, the study highlights the importance of subjective experiences and demographic factors in moderating this effect. This study adds to the ongoing research on psilocybin-assisted therapy by investigating contributing factors for optimizing this evolving type of therapy.
Efficacy and safety of microwave ablation in solitary kidney patients with T1a small renal masses
Authors: Justo-Jaume Carlos , Stempel Max , Qiu Jessica , Gonzalez Miranda Luis , Yan Guofen , Lyons Genevieve , Sands Kenneth , Schenkman Noah , Krupski Tracey , Culp Stephen , Lobo Jennifer 
Published: January 2025

Abstract
Objectives
To assess the safety and efficacy of using microwave ablation (MWA) to treat solitary kidney (SK) patients with T1a renal cell carcinoma (RCC).

Methods
Retrospective analysis of a prospectively maintained database identified patients with T1a RCC with either congenital or acquired SK. Estimated glomerular filtration rate (eGFR) was calculated from serum creatinine before MWA and after at 6 and 12 months post-procedure. The local recurrence-free survival (LRFS), metastatic-recurrence free survival (MRFS), cancer-specific survival, and overall survival were analyzed with the Kaplan–Meier method.

Results
A total of 26 patients met inclusion criteria, including 3 congenital and 23 acquired SK patients. eGFR was lower at both 6 and 12 months post-procedure compared to pre-procedure, with the congenital SK group having a more pronounced reduction in eGFR at both post-procedure timepoints. Median follow-up time was 28.6 months (IQR 12.4–55.4). Four patients (15.4%) experienced local recurrence. For LRFS, mean survival time was 69.4 months. There were 5 patients (19.2%) that experienced metastatic recurrence, with median and mean survival time at 101.1 and 82.0 months, respectively. The mean time for RCC-specific survival was 94.7 months, while median and mean time for overall survival was 43.1 and 61.7 months, respectively.

Conclusion
With a moderate reduction in renal function and a comparable rate of local recurrence compared to prior literature, this work demonstrates that MWA remains a viable alternative to more invasive techniques, particularly for high-risk SK patients with RCC. Our work highlights the need for further research on effectiveness of MWA in cancer control and preservation of renal function in larger cohorts of SK patients over extended follow-up times.
Asciminib resistance of a new BCR::ABL1 p.I293_K294insSSLRD mutant detected in a Ph + ALL patient
Authors: Cullot Grégoire , Lagarde Valérie , Cayuela Jean-Michel , Prouzet-Mauléon Valérie , Turcq Béatrice , Hicheri Yosr , Roy Lydia , Braun Thorsten , Mozziconacci Marie-Joelle , Alary Anne-Sophie , Dulucq Stéphanie 
Published: January 2025

AbstractChronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia patients largely benefit from an expanding tyrosine kinase inhibitors (TKIs) toolbox that has improved the outcome of both diseases. However, TKI success is continuously challenged by mutation-driven acquired resistance and therefore, close monitoring of clonal genetic diversity is necessary to ensure proper clinical management and adequate response to treatment. Here, we report the case of a ponatinib-resistant Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph + ALL) patient harboring a BCR::ABL1 p.I293_K294insSLLRD mutation. Using in vitro proliferation assays on newly generated Ba/F3 cell lines, we confirmed that the mutation confers moderate resistance to ponatinib, and to imatinib and nilotinib. In contrast, BCR::ABL1SLLRD Ba/F3 cells remain highly sensitive to dasatinib. Unexpectedly, the insertion also provides resistance to asciminib with no inhibitory effect up to 1000 nM. Based on predicted structural models, we speculate that the p.I293_K294insSLLRD disrupts the interaction between the SH3 domain and the kinase domain, shifting the equilibrium toward the active conformation. This shift confers resistance to TKIs that preferentially bind to the inactive conformation, as well as to the allosteric asciminib inhibitor. However, the mutation retains sensitivity to dasatinib, which targets the active form of the kinase.
Weak pairwise justifiability as a common root of Arrow’s and the Gibbard–Satterthwaite theorems
Authors: Barberà Salvador , Berga Dolors , Moreno Bernardo , Nicolò Antonio 
Published: January 2025

AbstractWe introduce a novel principle that we call weak pairwise justifiability, which applies to a large class of collective choice rules, including the social choice functions and the social welfare functions about which the Gibbard–Satterthwaite theorem and Arrow’s impossibility theorem are predicated, respectively. We prove that, under appropriate qualifications, our principle is a common root for these two classical results, when applied to rules defined over the full domain of weak preference orders (also for strict).
B-spline-based material point method with dynamic load balancing technique for large-scale simulation
Authors: Hidano Soma , Pan Shaoyuan , Yoshida Keina , Nomura Reika , Miki Yohei , Kawai Masatoshi , Moriguchi Shuji , Nakajima Kengo , Terada Kenjiro 
Published: January 2025

AbstractIn this study, a dynamic load-balancing (DLB) technique based on the sampling method is developed for MPMs using higher-order B-spline basis functions for parallel MPI calculations based on domain decomposition, in order to perform large-scale, long-duration landslide simulations in realistic computation time. Higher-order B-spline basis functions use a range of influence across cells compared to general basis functions, but this DLB technique dynamically adjusts the size of the computational domain according to the material point distribution, so that the material points are almost equally distributed across all cores. This allows the load bias between cores to be mitigated and the advantages of parallel computation to be fully exploited. Specifically, the novel contribution of this study is that the domain decomposition allows for proper communication between control points, even if the physical regions of the cores are staggered or non-adjacent, and even if the area of influence of B-spline basis functions spans multiple subdomains at this time. In numerical examples, the quasi-3D benchmark solid column collapse problem is computed for multiple core configurations to verify the effectiveness of the DLB method in terms of scalability and parallelization efficiency. The simulation of the full 3D column collapse problem also illustrates the applicability of the proposed DLB method to large-scale disaster simulations. Finally, to demonstrate the promise and capability of the DLB technique in the MPM algorithm, a full-scale size landslide disaster simulation is carried out to illustrate that it can withstand some practical size calculations.
Introducing the forearm fracture index to define the diametaphyseal junction zone through clinical evaluation in a cohort of 366 diametaphyseal radius fractures
Authors: von Schrottenberg Christoph , Beck Ricardo , Beck Susann Marie , Kruppa Christian , Kuhn Matthias , Schwerk Philipp , Fitze Guido , Schultz Jurek 
Published: January 2025

Abstract
Background
Unstable diametaphyseal radius fractures (DMRFs) can be prone to complications, and treatment strategies are heterogeneous. Studies are difficult to interpret as definitions of the diametaphyseal junction zone (DMJZ) are impractical for clinical use, imprecise, or prone to error.

Methods
We introduce the forearm fracture index (FFI) to define DMRFs in radiographs and ultrasound. The FFI is calculated by the ratio of the fracture’s distance to the distal radius growth plate over the width of the radius growth plate. The higher the FFI, the more proximal the fracture is. We define DMRFs to have an FFI between 1 and 2. All DMRFs treated at our institution between 2010 and 2020 were identified, and demographic data, fracture characteristics, and therapeutic strategies were assessed retrospectively. Comparative sub-analysis was performed between DMRFs(−) as defined in previous publications (Lieber in Unfallchirurg 114:292–299, 2011) and DMRFs( +) that were more proximal but still met our criteria.

Results
516 DMRFs were identified, representing 13.0% of all screened radius fractures. Excluding buckle fractures and patients lost to follow-up, 366 DMRFs were eligible for further analysis. Conservatively managed DMRFs were more distal than those managed operatively, represented by a lower FFI (1.28 vs. 1.34, p = 0.0051). 21 (5.7%) of all DMRFs were identified as DMRFs( +). These were significantly more dislocated and necessitated surgery more often than DMRFs(−) (52.4 vs. 24.6%, p = 0.009).

Conclusions
The FFI may be a good tool to identify and describe DMRFs. It can help guiding treatment decisions and make future studies on this entity more comparable.

Level of evidence
Study of Diagnostic Test, Level II.
Tensorial inversion of fourth-order material tensor: orthotropy and transverse isotropy
Authors: Hartmann Stefan , Schröder Jörg 
Published: January 2025

Abstract
In the theory of anisotropic linear elasticity, there are different approaches to define the elasticity in a coordinate-dependent relation by matrices—commonly, the Voigt-notation—or tensorial expressions using fourth-order tensors. In view of numerical treatment, for example, the finite element method, the stress state is defined by the strain state via the fourth-order elasticity tensor,

$$\textbf{T} = {\pmb {\mathcal {{C}}}} \textbf{E}$$

T
=

C

E

. In view of analytical considerations required, for instance, for parameter identification purposes, the inverse relation

$$\textbf{E} = {\pmb {\mathcal {{C}}}}^{-1} \textbf{T}$$

E
=

C

-
1

T

is necessary. In this paper, the inversion of the fourth-order representation is developed in a coordinate-free representation. using the concept of invariant theory, which is based on the principal invariants and the so-called mixed invariants of the strain tensor/stress tensor. The mixed invariants are defined in terms of the structural tensors, which represent the preferred directions of the material under consideration. The advantage here is that the constitutive equations for the anisotropic material (which are invariant under the elements of the material symmetry group) can be represented as isotopic tensor functions. Thus, the compliance tensor

$${\pmb {\mathcal {{C}}}}^{-1}$$

C

-
1

can be obtained for any orientation of the anisotropy axes. We limit ourselves here to the case of transverse isotropy and orthotropy in a coordinate invariant representation.
Institutional Investors with Disciplinary History and CSR Behavior of Investee Firms
Authors: Bonsall IV Samuel B. , Mammadov Babak , Zykaj Blerina Bela 
Published: January 2025

AbstractThis study explores how the prior unethical behavior of institutional investors impacts the corporate social responsibility (CSR) activities of the companies in which they invest. To identify such behavior, we focus on violations of laws and regulations by Registered Investment Advisers as reported to the Securities and Exchange Commission. Our findings reveal that these investors discourage firms’ engagement in CSR activities within their investee firms, which we attribute to institutions’ disregard for social norms. Our inferences remain unchanged with alternative identification strategies and more stringent definitions of unethical behavior, suggesting that endogeneity bias and construct validity issues do not explain our baseline results. Additionally, we find that statements by these investors in support of CSR initiatives appear hypocritical, as they fail to mitigate the negative consequences of their ownership on CSR activities. Overall, our study suggests that institutional investors’ prior unethical behavior influences their governance activities, generating negative social externalities.
Understanding the Douglas–Rachford splitting method through the lenses of Moreau-type envelopes
Authors: Atenas Felipe 
Published: January 2025

AbstractWe analyze the Douglas–Rachford splitting method for weakly convex optimization problems, by the token of the Douglas–Rachford envelope, a merit function akin to the Moreau envelope. First, we use epi-convergence techniques to show that this artifact approximates the original objective function via epigraphs. Secondly, we present how global convergence and local linear convergence rates for Douglas–Rachford splitting can be obtained using such envelope, under mild regularity assumptions. The keystone of the convergence analysis is the fact that the Douglas–Rachford envelope satisfies a sufficient descent inequality alongside the generated sequence, a feature that allows us to use arguments usually employed for descent methods. We report numerical experiments that use weakly convex penalty functions, which are comparable with the known behavior of the method in the convex case.
The Lady and the Plants: Two Notions of Teleology in Agnes Arber’s Philosophy of Plants
Authors: Straetmanns Vera Maximilia 
Published: January 2025

Abstract
Agnes Arber (1879–1960) was a British plant morphologist, historian of botany, and philosopher of biology. Though now largely forgotten, her work offers valuable insights into morphological as well as philosophical issues. This paper focuses on Arber’s work on teleology in plants. After providing a brief overview of her life and distinct style of work, two notions of teleology are presented, which become apparent in Arber’s morphological and philosophical work. The first notion, labeled final teleology, is based on Aristotle’s final cause and deals with adaptation-based explanations in biology. The second is labeled formal teleology. It is grounded in the Aristotelian formal cause and deals with the inherent directiveness of developing structures and the actualization of potentialities in organisms and their parts. Whereas Arber showed a reserved and skeptical attitude towards final teleology, she was very sympathetic to formal teleology, building her general morphological framework on it. Two examples from Arber’s work are then given, which illustrate how formal teleology informed her theorizing: the partial-shoot theory of the leaf, and parallelism in evolution as a counter-proposal to natural selection. Finally, Arber’s teleological interpretation of plant morphology is historically contextualized and connected to recent research developments in evolutionary biology and plant morphology.
Implications of freeboard policy for homeowners in different income-groups: A case study of Jefferson parish
Authors: Deria Anisha , Mostafiz Rubayet Bin , Lee Yong-Cheol , Friedland Carol J. 
Published: January 2025

Abstract
The National Flood Insurance Program (NFIP) encourages the adoption of at least a 1ft. freeboard against flooding. Though freeboard is an effective flood mitigation method, the strategy involves additional investment that may cause economic liabilities. Moreover, such strategies are often generalized and do not consider optimal requirements at the micro-level. To this end, this study identifies the factors of economic vulnerability and proposes a framework for investigating the implications of such policy on different income groups. The discriminant analysis method was used to empirically quantify vulnerability and identify factors that are significant contributors to vulnerability. In addition, a vulnerability-benefit analysis was conducted by quantifying the benefits in terms of savings. The framework has been elucidated with a case study conducted for a group of cities in Jefferson parish with a poverty rate of 20% or more. It was found that though economic vulnerability increased with a decrease in income level, the benefits associated with the use of freeboard were almost equally distributed across all levels of vulnerability. The framework developed in this study is expected to provide helpful insight regarding the impact of different policies formulated for mitigating and managing flood disasters on various population groups at the micro-level.
Make it or leave it?– An exploration of post-foundation dynamics among female entrepreneurs
Authors: Uebbing Lina , Wehner Marius Claus , Aránega Alba Yela , Guaita Martínez José Manuel 
Published: January 2025

AbstractFemale entrepreneurs encounter several barriers before starting a business. The prevalent association of entrepreneurship with masculine stereotypes in many countries is a contributing factor as to why fewer women pursue entrepreneurial ventures. Yet our understanding of whether these barriers vanish once females have founded a new business remains limited. To shed more light on women’s experiences, we conducted 32 semi-structured interviews to investigate German female entrepreneurs’ perceptions of challenges post-foundation. Our findings show that female entrepreneurs are still affected by stereotypes of their private and professional surroundings after their business has launched. The main reasons for exiting their businesses are experienced role conflicts that may result in mental health issues. Based on these findings, we developed a framework illustrating how women navigate through the entrepreneurial lifecycle, encountering increased role incongruity as they become more deeply immersed in the entrepreneurial environment. Understanding the factors through which women decide about their future paths is important for researchers and practitioners to support female entrepreneurs after new business startup. We conclude that sustained private and professional as well as instrumental and non-instrumental support during the early stages after starting a new venture may help sustain the share of female entrepreneurs and reduce the share of females resigning and going into other labor.
An example of fractional ODE loss of maximum principle and Hopf’s lemma
Authors: Li Yulong , Raihen Md Nurul , Çelik Emine , Telyakovskiy Aleksey S. 
Published: January 2025

AbstractIt has been known that the fractional ODEs involving Riemann–Liouville fractional derivatives maintain many “analogies” of the classic elliptic-type properties, including maximum principles, Hopf’s Lemma, the existence of real eigenvalues, etc. However, in this short work, we construct a counterexample demonstrating that Caputo-type fractional operators (and their compositions) fail to uphold the maximum principle and Hopf’s lemma. This finding is somewhat unexpected and serves as a benchmark problem or counterexample, reminding us to remain cautious when developing parallel theories for fractional differential equations and applying them in modeling. Since the maximum principle and Hopf’s lemma are often used to construct convex cones in Banach spaces and guarantee the existence of a principal eigenvalue in classical elliptic theory, this result leads us to conjecture that fractional Sturm–Liouville problems involving the Caputo fractional derivative may lack a conventional principal eigenvalue. This conjecture is partially proved in a following-up work.