bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhanced bone cement for fixation of prosthetic joint utilizing nanoparticles
Authors: Gamal Safaa , Mikhail Mina , Salem Nancy , EL-Wakad Mohamed Tarek , Abdelbaset Reda 
Published: January 2025

Abstract
Bone cement is commonly utilized to secure prosthetic joints in the body because of its robust fixation, stability, biocompatibility, and immediate load-bearing capability. However, issues such as loosening, leakage, and insufficient bioactivity can lead to its failure. Therefore, improving its mechanical, physical, and biological properties is crucial for enhancing its efficiency. This study examines the impact of incorporating four different nanomaterials—Titanium Dioxide (TiO2), Magnesium Oxide (MgO), Calcium Phosphate (Ca3(PO4)2), and Alumina Oxide (Al2O3)—into bone cement on its mechanical, physical, and biological properties. TiO2 and Al2O3 nanoparticles are selected to enhance the compression strength of bone cement, thereby preventing loosening. Magnesium Oxide (MgO) and Ca3(PO4)2 nanoparticles are chosen to improve cell adhesion and reducing the risk of cement leakage. Five specimens were prepared: the first with 100% pure bone cement powder, the second with 98% pure bone cement powder and modified with 2% MgO and TiO2, and the remaining three with 95% pure bone cement powder and modified with 5% varying ratios of MgO, TiO2, Ca3(PO4)2, and Al2O3. Compression, tensile, hardness, and bending strengths were assessed to determine improvements in mechanical properties. Setting temperature, porosity, and degradation were measured to evaluate physical properties. Cell adhesion and toxicity tests were conducted to examine the surface structure and biological properties. The results demonstrated that the modified specimens increased compression strength by 8.14%, tensile strength by 3.4%, and bending strength by 4.96%. Porosity, degradation, and setting temperature in modified specimens increased by 3.24%, 0.64%, and 5.17% respectively pure bone cement values. Cell adhesion in modified bone cement specimens showed normal attachment when scanned with FE-SEM. All of the tested modified specimens showed no toxicity, except for specimens with 2% Al2O3 that showed 25% toxicity which could be averted by employing antibiotics.

Graphical Abstract
Factors Associated with the Timing of Initial Visit to Healthcare Providers for Injured Workers with Low Back Pain Claims: A Multijurisdiction Retrospective Cohort
Authors: Mekonnen Tesfaye Hambisa , Russell Grant , Sheehan Luke R. , Collie Alex , Di Donato Michael 
Published: January 2025

Abstract

Purpose
Evidence shows that patient outcomes following musculoskeletal injury have been associated with the timing of care. Despite the increasing number of injured workers presenting with low back pain (LBP) in primary care, little is known about the factors that are associated with the timing of initial healthcare provider visits. This study investigated factors that are associated with the timing of initial workers’ compensation (WC)-funded care provider visits for LBP claims.

Methods
We used a retrospective cohort design. A standardised multi-jurisdiction database of LBP claims with injury dates from July 2011 to June 2015 was analysed. Determinants of the time to initial general practitioner (GPs) and or musculoskeletal (MSK) therapists were investigated using an accelerated failure time model, with a time ratio (TR) > 1 indicating a longer time to initial healthcare provider visit.

Results
9088 LBP claims were included. The median time to first healthcare provider visit was 3 days (interquartile range (IQR) 1–9). Compared to General practitioners (GPs) (median 3 days, IQR 1–8), the timing of initial consultation was longer if the first healthcare providers were MSK therapists (median 5 days, IQR 2–14) (p < 0.001). Female workers had a shorter time to first healthcare provider visit [TR = 0.87; 95% CI (0.78, 0.97)] compared to males. It took twice as long to see MSK therapists first as it did to see GPs for injured workers [TR = 2.12; 95% CI (1.88, 2.40)]. Professional workers and those from remote areas also experienced delayed initial healthcare provider visits.

Conclusions
The time to initial healthcare provider visit for compensable LBP varied significantly by certain occupational and contextual factors. Further research is needed to investigate the impact of the timing of initial visits to healthcare providers on claim outcomes.
Offshore renewable energy SMEs’ innovation interactions across the triple helix: a management as practice perspective
Authors: Barrett Gillian , Crowley Frank 
Published: January 2025

Abstract
Offshore Renewable Energy (ORE) could be pivotal in combating climate change, offering reliable and sustainable energy with less intermittency than other renewables. However, unlocking its potential requires robust collaboration across many different actors. The purpose of this study is to explore the ‘human element’ of how SME leadership manage the technology transfer process and the underlying inter-organisational interactions across the triple helix. To achieve this, we adopt a management as practice perspective using Whittington’s (2016) framework, which delineates praxis, practices, and practitioners. The research study employed a multiple case study design, and the primary sample included eight European ORE SME case studies. The study finds SMEs operate within a heavily strained triple helix environment, requiring them to navigate complex bureaucratic dynamics with universities and government partners. This is further compounded by fragmented governance structures across the EU, making collaboration reliant on forging strategic alliances. We find that the ‘human element’ within SMEs embodying an innate blend of ability, experience, pragmatism, and adaptability is central to executing successful interactions. We discuss the policies needed for ORE SMEs to navigate the multifaceted challenges surrounding the human element of triple helix interactions.
Social Determinants, Mental Well-Being, and Disrupted Life Transitions Among Young Adults with Disabling Mental Health Conditions
Authors: Cook Judith A. , Jonikas Jessica A. , Burke-Miller Jane K. , Aranda Frances , Mullen Michelle G. , Davis Maryann , Sabella Kathryn 
Published: January 2025

Abstract
This study sought to understand how young adults (age 18–25) with histories of mental health disorders are coping with disrupted transitions to adulthood during the COVID-19 pandemic. A cross-sectional web survey was conducted in March–June 2021 of 967 US young adults with pre-pandemic psychiatric disability to assess their current psychiatric status, interrupted transitions, and associations with social determinants including income, community participation, and social context. Mental health was assessed with the Patient Health Questionnaire (PHQ-9), Generalized Anxiety Disorder Scale (GAD-7), and PTSD Checklist-Civilian Version. Social determinants were identified with the Epidemic-Pandemic Impacts Inventory. Interrupted transitions were measured with the Young Adult Disrupted Transitions Assessment. Multivariable logistic regression models predicted four types of transition disruptions and associations with current mental health, social determinants, and demographic factors. Disruptions were reported by 81.1% including interrupted education completion (38.3%), employment careers (37.6%), residential independence (27.7%), and intimate partner relationships (22.9%). Many screened positive for major depressive disorder (81.7%), PTSD (85.5%), or GAD (58.6%). Disruption in establishing intimate partner relationships was associated with depression, anxiety, and PTSD. Interrupted residential independence was associated with anxiety. Interrupted education completion was associated with PTSD. Interrupted employment was associated with anxiety. Social determinants significant in these models included social connections, community participation, income, and racial/ethnic identification. Results illuminate ways that current mental health and social determinants affect transition interruptions during the pandemic. Findings suggest the need for interdisciplinary approaches, integrated models of care, and assistance accessing treatment, rehabilitation, and community support services from adult service systems.
Incidence and Prevalence of Post-COVID-19 Myalgic Encephalomyelitis: A Report from the Observational RECOVER-Adult Study
Authors: Vernon Suzanne D. , Zheng Tianyu , Do Hyungrok , Marconi Vincent C. , Jason Leonard A. , Singer Nora G. , Natelson Benjamin H. , Sherif Zaki A. , Bonilla Hector Fabio , Taylor Emily , Mullington Janet M. , Ashktorab Hassan , Laiyemo Adeyinka O. , Brim Hassan , Patterson Thomas F. , Akintonwa Teresa T. , Sekar Anisha , Peluso Michael J. , Maniar Nikita , Bateman Lucinda , Horwitz Leora I. , Hess Rachel ,   on behalf of the NIH Researching COVID to Enhance Recovery (RECOVER) Consortium
Published: January 2025

Abstract

Background
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) may occur after infection. How often people develop ME/CFS after SARS-CoV-2 infection is unknown.

Objective
To determine the incidence and prevalence of post-COVID-19 ME/CFS among adults enrolled in the Researching COVID to Enhance Recovery (RECOVER-Adult) study.

Design, Setting, and Participants
RECOVER-Adult is a longitudinal observational cohort study conducted across the U.S. We included participants who had a study visit at least 6 months after infection and had no pre-existing ME/CFS, grouped as (1) acute infected, enrolled within 30 days of infection or enrolled as uninfected who became infected (n=4515); (2) post-acute infected, enrolled greater than 30 days after infection (n=7270); and (3) uninfected (1439).

Measurements
Incidence rate and prevalence of post-COVID-19 ME/CFS based on the 2015 Institute of Medicine ME/CFS clinical diagnostic criteria.

Results
The incidence rate of ME/CFS in participants followed from time of SARS-CoV-2 infection was 2.66 (95% CI 2.63–2.70) per 100 person-years while the rate in matched uninfected participants was 0.93 (95% CI 0.91–10.95) per 100 person-years: a hazard ratio of 4.93 (95% CI 3.62–6.71). The proportion of all RECOVER-Adult participants that met criteria for ME/CFS following SARS-CoV-2 infection was 4.5% (531 of 11,785) compared to 0.6% (9 of 1439) in uninfected participants. Post-exertional malaise was the most common ME/CFS symptom in infected participants (24.0%, 2830 of 11,785). Most participants with post-COVID-19 ME/CFS also met RECOVER criteria for long COVID (88.7%, 471 of 531).

Limitations
The ME/CFS clinical diagnostic criteria uses self-reported symptoms. Symptoms can wax and wane.

Conclusion
ME/CFS is a diagnosable sequela that develops at an increased rate following SARS-CoV-2 infection. RECOVER provides an unprecedented opportunity to study post-COVID-19 ME/CFS.
Robust semi-supervised learning in open environments
Authors: Guo Lan-Zhe , Jia Lin-Han , Shao Jie-Jing , Li Yu-Feng 
Published: January 2025

Abstract
Semi-supervised learning (SSL) aims to improve performance by exploiting unlabeled data when labels are scarce. Conventional SSL studies typically assume close environments where important factors (e.g., label, feature, distribution) between labeled and unlabeled data are consistent. However, more practical tasks involve open environments where important factors between labeled and unlabeled data are inconsistent. It has been reported that exploiting inconsistent unlabeled data causes severe performance degradation, even worse than the simple supervised learning baseline. Manually verifying the quality of unlabeled data is not desirable, therefore, it is important to study robust SSL with inconsistent unlabeled data in open environments. This paper briefly introduces some advances in this line of research, focusing on techniques concerning label, feature, and data distribution inconsistency in SSL, and presents the evaluation benchmarks. Open research problems are also discussed for reference purposes.
Curative-Intended Management of Synchronous Esophageal and Rectal Cancer—A Systematic Literature Review
Authors: Wurschi Georg W. , Schneider Claus , Ernst Thomas , Helfritzsch Herry , Nowatschin Jens , Bitter Thomas , Freesmeyer Martin , Pietschmann Klaus , Römer Maximilian 
Published: January 2025

Abstract

Purpose
Synchronous esophageal (EC) and rectal carcinoma (RC) is a rare and challenging condition, particularly in curative-intended treatment. Especially locally advanced tumors may not be suitable for primary resection and require individual multimodal treatment. This review examines curative-intended management of synchronous EC and RC.

Material and Methods
A systematic literature search across five electronic databases according to the PRISMA guideline was conducted. Individual patient data was analyzed, including two additional cases from our institution.

Results
We identified 9 relevant cases from 1552 results. Additionally, two male patients (62 and 65 years old) from our institution were included. Both received 5-fluorouracil/cisplatin-based chemoradiotherapy (CRT) for EC. Sequential short-course radiation (SCRT) for RC was performed in one patient. After complete response (CR) in both tumors, no consecutive surgery was performed. He underwent resection for local recurrence of RC 11 months later and is currently considered as disease-free (30 months follow-up). The second patient underwent primary resection of RC and had early progression following resection of EC. We found that most patients had advanced EC (8/11), with the majority receiving neoadjuvant (5/11) or definitive treatment (3/11). Locally advanced RC was diagnosed in 5/11 patients, primarily treated with sequential resection. Pyrimidine-based systemic treatment was common. Four relapses and two deaths were reported, but median follow-up was 11 (range 1.5–30) months only.

Conclusion
The review suggests that neoadjuvant multimodal approaches may offer curative potential for synchronous EC and RC, with individualized treatment protocols adapted from single-cancer protocols. Nevertheless, data on long-term outcome is limited.
Making Migrants Deportable: The Internalization of Restrictive Policies Through Transferred Responsibility and Borrowed Legitimacy
Authors: Borrelli Lisa Marie 
Published: January 2025

Abstract
This paper explores the connection between social policy and immigration law as one feature of migration governance to advance internal bordering and border internalization. It argues that responsibility for migration governance is being transferred: from immigration authorities and the broader field of immigration policy to social services and the broader field of social policy. This allows for the outsourcing of immigration control to “new” sectors of society. In a second step, immigration authorities borrow legitimacy from social services and related actors involved in assessing non-citizens, thus turning reports from one policy field to the service of assessments made in another. This work draws on empirical data collected from Swiss immigration authorities (Migrationsdienste) and social services (Sozialdienste) whose work concerns migrants in receipt of social assistance. In Switzerland, powerful stereotypes shape the legal residency rights of non-citizens by portraying them as undeserving of welfare, reinforcing a strict citizen vs. non-citizen divide. As I argue, the connections between “workfarist” policies that characterize the Swiss welfare state and restrictive immigration policies legitimate the withdrawal of residence rights from non-citizens rendered destitute. The transfer of responsibility and borrowing of legitimacy facilitated by this entwinement of social policy and immigration law entrench processes of internal bordering. With formerly less related policy fields now increasingly charged with immigration-related decision making, the existing bordering practices of immigration authorities are expanded to encompass new actors. This close entwinement of different policy fields is characteristic of how contemporary societies police and control non-citizens.
Governing the emergence of network-driven platform ecosystems
Authors: Kari Arthur , Bellin Pepe , Matzner Martin , Gersch Martin 
Published: January 2025

Abstract
Literature on platform governance is focused on keystone organizations that exclusively own a platform and control its complementors and users. However, emerging network-driven platform ecosystems—such as European data spaces—represent a shift in focus by allowing stakeholders to share platform ownership and decision rights. To investigate this emerging phenomenon, we conduct a qualitative-explorative case study, interviewing 32 representatives of Catena-X, a European data space in the automotive industry. To conceptually grasp the co-development and management of network-driven platform ecosystems, we employ a network governance perspective as the theoretical lens. We contribute to platform governance literature with (1) a conceptualization of shared platform ownership recognizing the dichotomy of inner and outer governance, and (2) a process model and a conceptual model of an interorganizational network governing the emergence of a platform ecosystem.
On the fractal operator of a mixed possibly infinite iterated function system
Authors: Anghelina Bogdan Cristian , Miculescu Radu , Mihail Alexandru 
Published: January 2025

Abstract
In this paper we introduce a new class of iterated function systems. More precisely, we study the fractal operator associated with a mixed possibly infinite iterated function system (briefly mIIFS). Such a system is a possibly infinite iterated function system (i.e. a possibly infinite family of Banach contractions on a complete metric space, satisfying some extra conditions) enriched with an orbital possibly infinite iterated function system (i.e. a possible infinite family of nonexpansive functions which need not be Banach contractions on the entire previously mentioned complete metric space, but just on the orbits of the space’s elements). Our main result states that the fractal operator associated with an mIIFS is a weakly Picard operator. Its fixed points are called attractors of the system. We present concrete examples of mIIFSs and graphical representations of certain attractors’ approximates.
Supplementation Matters: Academic Impact of an Afterschool Tutoring Program in Timor-Leste
Authors: Yazdani Naisan 
Published: January 2025

Abstract
Students in Timor-Leste face low educational outcomes due to sociopolitical factors rooted in the nation’s colonial history. This study evaluates the academic impact of a low-resource afterschool supplementary tutoring program designed to address learning gaps and improve school outcomes across rural and urban settings. Using instructional design principles, the program employed worksheet-based individualized learning content in a familiar language, supported by personalized feedback. Pre- and post-test scores in mathematics and English were compared over 7 months between an intervention group and a comparison group, with results analyzed using a Welch t test. Findings revealed statistically significant improvements in both subjects, with greater gains in mathematics, suggesting an opportunity to explore alternative methods for English instruction, such as incorporating social interactions to support early learners. The study highlights the importance of community support, tutors’ capabilities, and their residence within local neighborhoods in sustaining the program. These results demonstrate the potential of well-structured afterschool programs to enhance educational outcomes in low-resource contexts, offering a scalable model for similar initiatives in emerging nations.
Advancements and challenges of onboard carbon capture and storage technologies for the maritime industry: a comprehensive review
Authors: Ahmed Yaseen Adnan , Lazakis Iraklis , Mallouppas George 
Published: January 2025

Abstract
In response to the growing demand of reducing greenhouse gas (GHG) emissions within maritime sector, Onboard Carbon Capture and Storage (OCCS) technologies provide as key solutions for tackling carbon dioxide (CO2) emissions from ships. This review paper offers a comprehensive overview of recent developments, challenges, and prospects of Carbon Capture and Storage (CCS) technologies considering specifically for onboard ship applications. Various Carbon Capture (CC) methods, ranging from post-combustion and pre-combustion capture to oxy-fuel combustion, are critically analysed concerning their operating principles, advantages, disadvantages and applicability in the maritime context. Temporary onboard CO2 storage is examined in its gaseous, supercritical, solid, and liquid states. In this regard, solid and liquid forms are found promising, although solid storage is not yet commercially mature. The review also addresses the challenges in implementing the CC technologies on ships, including space constraints, energy requirements, safety concerns, and economic viability. A comparative assessment is conducted to determine the most promising OCCS technologies. The study finds that post-combustion CC by chemical absorption requires more space than cryogenic and membrane separation, with the latter two deemed viable options, albeit with trade-offs in energy consumption and cost. The study would provide valuable insights and ideas for further research in the field of OCCS technologies.
Peer Violence Poly-victimization in Youth and Associations to Psychosomatic Symptoms — A Latent Class Analysis
Authors: Dahlqvist Heléne , Gådin Katja Gillander , Landstedt Evelina 
Published: January 2025

Abstract
Peer victimization is a common and complex issue among young people worldwide and is affecting mental health development during a critical developmental period in their lives. By means of a Latent Class Analysis (LCA), this study explores peer poly-victimization subgroups among adolescents and their association with psychosomatic symptoms. A sample of 1536 Swedish students in grades 7–9 completed an electronic questionnaire on various types of victimization over the past six months, including physical violence, as well as in-person and cyber sexual harassment and bullying. The LCA identified three subgroups for boys and four for girls, revealing a gendered pattern of victimization, especially in the case of sexualized violence, which was more prevalent among girls. In girls, this type of violence also increased with age. Victimization was strongly associated with psychosomatic symptoms across genders, with sexualized violence having more severe health consequences. The findings emphasize the need for preventive programs that avoids siloed interventions and instead targets multiple forms of violence, including online harassment, to promote adolescent mental health.