bluuebunny/crossref_metadata_2025_split huggingface dataset:
New Metrics to Probe the Dynamical State of Galaxy Clusters
Authors: Cerini Giulia , Cappelluti Nico , Natarajan Priyamvada 
Published: March 2023

Abstract
We present new diagnostic metrics to probe the dynamical state of galaxy clusters. These novel metrics rely on the computation of the power spectra of the matter and gas distributions and their cross-correlation derived from cluster observations. This analysis permits us to cross-correlate the fluctuations in the matter distribution, inferred from high-resolution lensing mass maps derived from Hubble Space Telescope (HST) data, with those derived from the emitted X-ray surface brightness distribution of the hot intracluster medium from the Chandra X-ray Observatory. These methodological tools allow us to quantify with unprecedented resolution the coherence with which the gas traces the mass and interrogate the assumption that the gas is in hydrostatic equilibrium with the underlying gravitational potential. We characterize departures from equilibrium as a function of scale with a new gas-mass coherence parameter. The efficacy of these metrics is demonstrated by applying them to the analysis of two representative clusters known to be in different dynamical states: the massive merging cluster A2744, from the HST Frontier Fields sample, and the dynamically relaxed cluster A383, from the Cluster Lensing and Supernova Survey with the Hubble sample. Using lensing mass maps in combination with archival Chandra data, and simulated cluster analogs available from the OMEGA500 suite, we quantify the fluctuations in the mass and X-ray surface brightness and show that new insights into the dynamical state of the clusters can be obtained from our gas-mass coherence analysis.
Ambipolar Heating of Magnetars
Authors: Tsuruta Sachiko , Kelly Madeline J. , Nomoto Ken’ichi , Mori Kanji , Teter Marcus , Liebmann Andrew C. 
Published: March 2023

Abstract
Magnetars, neutron stars thought to be with ultrastrong magnetic fields of 1014–15 G, are observed to be much hotter than ordinary pulsars with ∼1012 G, and additional heating sources are required. One possibility is heating by the ambipolar diffusion in the stellar core. This scenario is examined by calculating the models using the relativistic thermal evolutionary code without making the isothermal approximation. The results show that this scenario can be consistent with most of the observed magnetar temperature data.
Bumblebee Black Holes in Light of Event Horizon Telescope Observations
Authors: Xu Rui , Liang Dicong , Shao Lijing 
Published: March 2023

Abstract
We report the existence of novel static spherical black hole solutions in a vector–tensor gravitational theory called the bumblebee gravity model, which extends the Einstein–Maxwell theory by allowing the vector to nonminimally couple to the Ricci curvature tensor. A test of the solutions in the strong-field regime is performed for the first time using the recent observations of the supermassive black hole shadows in the galaxy M87 and the Milky Way from the Event Horizon Telescope Collaboration. The parameter space is found largely unexcluded and more experiments are needed to fully bind the theory.
Comet P/2021 HS (PANSTARRS) and the Challenge of Detecting Low-activity Comets
Authors: Ye 叶 Quanzhi 泉志 , Kelley Michael S. P. , Bauer James M. , Farnham Tony L. , Bodewits Dennis , Buzzi Luca , Weryk Robert , Masci Frank J. , Medford Michael S. , Riddle Reed , Wold Avery 
Published: March 2023

Abstract
Jupiter-family comet (JFC) P/2021 HS (PANSTARRS) only exhibits a coma within a few weeks of its perihelion passage at 0.8 au, which is atypical for a comet. Here we present an investigation into the underlying cause using serendipitous survey detections and targeted observations. We find that the detection of the activity is caused by an extremely faint coma being enhanced by the forward scattering effect owing to the comet reaching a phase angle of ∼140°. The coma morphology is consistent with sustained, sublimation-driven activity produced by a small active area, ∼700 m2, one of the smallest values ever measured on a comet. The phase function of the nucleus shows a phase coefficient of 0.035 ± 0.002 mag deg−1, implying an absolute magnitude of H = 18.31 ± 0.04 and a phase slope of G = − 0.13, with color consistent with typical JFC nuclei. Thermal observations suggest a nucleus diameter of 0.6–1.1 km, implying an optical albedo of 0.04–0.23, which is higher than typical cometary nuclei. An unsuccessful search for dust trail and meteor activity confirms minimal dust deposit along the orbit, totaling ≲108 kg. As P/2021 HS is dynamically unstable, similar to typical JFCs, we speculate that it has an origin in the trans-Neptunian region and that its extreme depletion of volatiles is caused by a large number of previous passages to the inner solar system. The dramatic discovery of the cometary nature of P/2021 HS highlights the challenges of detecting comets with extremely low activity levels. Observations at high phase angle, where forward scattering is pronounced, will help identify such comets.
Spiders (Araneae) of the northeast of the Luhansk Oblast (Ukraine)
Authors: Polchaninova Nina , Marushchak Oleksii 
Published: March 2023

The dataset contains records of spiders collected in the northeast of Luhansk Oblast in the periods 1982-1989, 2009-2011 and 2021. It aimed at the inventory of spider fauna of the Striltsivskyi Steppe Nature Reserve and species distribution in the main grassland and forest habitats of the region. The research was also concerned with the impact of conservation management ‒ hay mowing or strict protection and man-induced steppe fire on spider communities.
The dataset includes records from seven geographical localities in the northeast of Luhansk Oblast with 1,955 occurrences of 6662 individuals. For the first time, it provides detailed information about spider species composition, phenology and habitat distiribution within the study area, including two conservation areas and the primary material on the studies on the impact of hay making and steppe fire on spider communities. All the records of 246 spider species with georeferencing were published in GBIF.
New relevant chorological and conservation data on Carex (Cyperaceae) and Hypericum (Hypericaceae) from Ecuador
Authors: Jiménez-Mejías Pedro , Morales-Alonso Ana , Oleas Nora , Sánchez Enmily , Martín-Bravo Santiago , Masa-Iranzo Irene , S. Meseguer Andrea 
Published: March 2023

Knowledge of Carex L. (true sedges) and Hypericum L. (St. John's wort) in the Neotropics is fragmentary.
As a result of a fieldwork campaign in Ecuador and revision of herbarium collections (K, QCA and QCNE), we present here relevant records of twelve Carex (Cyperaceae) and four Hypericum (Hypericaceae) species. Regarding Carex, we present the novel report for South America of C. aztecica, as well as the first Ecuadorian records for C. brehmeri, C. collumanthus, C. fecunda, C. melanocystis and C. punicola. The three later records have additional biogeographical significance, as they represent the new northern limit of these species. We also include observations for another five species included in the Ecuadorian Red List of Endemic Plants. As a result, the list of native Carex reported for Ecuador would now include 52 taxa. With regard to Hypericum, we include the new report of H. sprucei for the province of Bolívar, and the confirmation of the presence of three rare species (H. acostanum, H. matangense, H. prietoi) in their type localities, although with extremely low population sizes. We discuss their conservation status and implications.
Les psychédéliques, nouvelles perspectives pour les thérapies du traumatisme
Authors: Josse Évelyne , Baliko Christophe , Dubus Zoë 
Published: March 2023

Les psychothérapies axées sur le traumatisme sont généralement préconisées comme traitement de première intention pour les TSPT et les antidépresseurs ISRS comme traitement de deuxième ligne. Néanmoins, les taux importants d’abandon en cours de traitement, tant psychothérapeutique que médicamenteux, et le nombre de personnes continuant à souffrir malgré une ou plusieurs tentatives de prise en charge indiquent que l’offre de soins actuelle ne répond pas aux besoins de nombreux patients. En 1971, la Convention sur les substances psychotropes, coordonnée par l’ONU, a classé les psychédéliques dans les substances dangereuses sans réelle valeur thérapeutique. Toutefois, depuis une vingtaine d’années, des centres de recherches obtiennent des dérogations pour mener des essais cliniques. Ces substances ouvrent des perspectives thérapeutiques alternatives prometteuses dans le traitement de troubles de stress post-traumatique sévère. La première étude de phase 3, randomisée, multisite, en double aveugle, contrôlée par placebo, montre une amélioration cliniquement significative des symptômes de TSPT chez 88 % des patients et 67 % ne remplissent plus les conditions requises pour un diagnostic de TSPT. Les PDL réduisent non seulement les symptômes traumatiques, mais favorisent également la croissance post-traumatique. Ces substances se sont aussi montrées efficaces à réduire les troubles du sommeil, l’anxiété sociale, l’addiction à l’alcool et aux drogues et les troubles alimentaires chez les patients souffrant de TSTP. Le degré de l’expérience « mystique » est apparu comme prédicteur de changements à long terme. Les psychédéliques combinés à la psychothérapie présentent des avantages par rapport aux médicaments existants utilisés comme traitement de première intention du TSPT en termes de profil de sécurité et d’effets secondaires, d’efficacité et de durée de rémission. Toutefois, le profil de sécurité des PDL peut varier en fonction du contexte dans lequel ils sont utilisés. Peu d’effets secondaires négatifs durables et d’incidents graves sont signalés, mais des réactions indésirables passagères sont fréquentes. Des cas très rares de trouble persistant des perceptions dû aux hallucinogènes caractérisé par des symptômes perceptifs, principalement visuels, prolongés ou récurrents, sont rapportés, généralement lorsqu’ils sont consommés dans un cadre récréatif. L’expérience vécue sous psychédélique est fortement influencée par la disposition psychologique du sujet et par le cadre dans lequel elle se déroule. Le concept de «set and setting» désigne les paramètres non-médicamenteux de l’expérience qui façonnent la réponse aux substances psychédéliques. La thérapie assistée par psychédéliques débute par quelques entretiens préparatoires, se poursuit par la séance d’administration du psychédélique et continue par des séances d’intégration avec un thérapeute.
Psychothérapie transculturelle. Décentrage et contre-transfert
Authors: Lesœurs Guy , Ferradji Taieb 
Published: March 2023

En présence d’un patient, migrant et ou porteur d’une autre culture, le psychothérapeute, quelle que soit sa pratique clinique (analytique, systémique, cognitivo-comportementaliste etc.), en plus de l’indispensable empathie, doit s’adapter à la personne et à son histoire, par une posture authentique et consciente, intégrant la tolérance à la différence culturelle, le respect des croyances sans imposition de ses propres schémas culturels et même… en abandonnant, pour un temps, son savoir de soignant. Ce décentrage de sa propre culture et même de son savoir de thérapeute lui permet de ne pas comparer, de ne pas imposer l’image de soi et de son groupe d’appartenance, afin de ne pas stigmatiser et focaliser sur les carences ou les attributs qu’il peut trouver « exotiques » chez l’autre, étranger à sa propre culture. La posture transculturelle n’est pas donnée d’emblée mais nécessite un apprentissage afin d’établir l’alliance thérapeutique, prérequis à la relation transféro-contre-transférentielle.
The effect of melatonin on cognitive functions following coronary artery bypass grafting: A triple-blind randomized-controlled trial
Authors: Jouybar Reza , Zohoori Kambiz , Khademi Saeed , Akhlagh Seyed Hedayatallah , Mani Arash , Akhlagh Seyed Amir reza , Asadpour Elham 
Published: March 2023

Background:
Cognitive dysfunction presents one of the chief causes of postoperative morbidity. Melatonin as a neurohormone can improve neurocognitive functioning and sleep disorders. We evaluated the effect of melatonin on the postoperative cognitive function of patients undergoing coronary artery bypass grafting (CABG).

Materials and Methods:
A triple-blind randomized-controlled trial was conducted on 66 CABG candidates in Namazee Hospital (Shiraz, Iran). Patients were assigned equally into two groups receiving melatonin 10 mg or a placebo daily for 4 weeks before surgery and 2 days after surgery in the intensive care unit. The Mini-Mental State Examination (MMSE), Tower of London (ToL), and Wechsler Adults Intelligence Scale-Revised (WAIS-R) cognitive function tests were performed in both groups 4 weeks before surgery (time point 1), 2 days after surgery (time point 2), and 6 weeks after initial administration of melatonin (time point 3).

Results:
The mean change score (time point 3-time point 1) differed significantly between the two groups in the MMSE (P ≤ 0.001), ToL total score (P = 0.001), and WAIS-R general IQ (P ≤ 0.001), picture completion (P ≤ 0.001), vocabulary (P = 0.024), and digit span (P = 0.01). On the other hand, no significant differences were detected in the WAIS-R block design, ToL total time delay, ToL total lab, and ToL total result scores.

Conclusion:
The MMSE and WAIS-R tests revealed that melatonin might have prophylactic effects against postoperative cognitive disturbance in patients undergoing elective CABG.
Serum cystatin C and βeta-2 microglobulin as potential biomarkers in children with lupus nephritis
Authors: Baraka Eman , Hashaad Nashwa , Abdelhalim Walid , Elolemy Gehan 
Published: March 2023

Objectives: In this study, we aimed to assess serum levels of Cystatin C (Cys C) and beta-2 microglobulin (β2M) in juvenile systemic lupus erythematosus (JSLE) patients and to investigate their role as potential biomarkers of lupus nephritis (LN) and overall disease activity.
Patients and methods: Between December 2018 and November 2019, a total of 40 patients with JSLE (11 males, 29 females; mean age: 12.6±2.5 years; range, 7.5 to 16 years) and 40 age- and sex-matched controls (10 males, 30 females; mean age: 12.3±2.4 years; range, 7 to 16 years) were included in this study. Serum (s) Cys C and β2M levels were compared between the groups. The SLE Disease Activity Index (SLEDAI-2K), the renal SLEDAI (rSLEDAI), and the Renal Damage Index were used.
Results: JSLE patients had significantly elevated mean sCyc C and sβ2M levels (1.4±0.8 mg/mL and 2.8±0.9 mg/mL, respectively) compared to the controls (0.6±0.1 mg/mL and 2.0±0.2 mg/mL, respectively; p<0.00). The mean sCys C and sβ2M levels were significantly higher in the LN group, compared to non-LN patients (1.8±0.7 mg/mL and 3.1±1.0 mg/mL, respectively vs. 0.8±0.3 mg/mL and 2.4±0.6 mg/mL, respectively; p=0.002 and p=0.02, respectively). The sCys C levels had significant positive correlations with erythrocyte sedimentation rate (r=0.3, p=0.05), serum creatinine (r=0.41, p= 0.007), 24-h urinary protein (r=0.58, p<0.001), anti-double stranded deoxyribonucleic acid antibodies titers (r=0.55, p=0.002), extra-renal SLEDAI scores (r=0.36, p=0.04), rSLEDAI (r=0.46, p=0.002), and renal class (r=0.7, p=0.0001). Serum β2M levels were significantly negatively correlated with complement 4 levels (r=-0.31, p=0.04) and significantly positively correlated with extra-renal SLEDAI scores (r=0.3, p=0.05).
Conclusion: These findings confirm that sCys C and sβ2M levels are increased in JSLE patients in association with the overall active disease. However, sCys C level may act as a promising non-invasive biomarker for predicting kidney disease activity and biopsy classes in children with JSLE.
Salivary anti-cyclic citrullinated peptide as a screening tool for rheumatoid arthritis
Authors: Mortazavi Nazanin , Abdolahi Nafiseh , Saeidi Mohsen , Ali Vakili Mohammad , Mohebrad Pouria 
Published: March 2023

Objectives: This study aims to evaluate the sensitivity and specificity of salivary anti-cyclic citrullinated peptide 3 (anti-CCP3) for the early diagnosis of rheumatoid arthritis.
Patients and methods: Between June 2017 and April 2019, a total of 63 patients with rheumatoid arthritis (10 males, 53 females; mean age: 50.4±9.5 years; range, 27 to 74 years) and 49 healthy controls (8 males, 41 females; mean age: 49.3±9.3 years; range 27 to 67 years) were included. Salivary samples were collected by passive drooling. Anti-cyclic citrullinated peptide analyses of salivary and serum samples were performed.
Results: The mean polyclonal immunoglobulin (Ig)G-IgA anti-CCP3 salivary levels were significantly different in patients (149.2±134.2) compared to healthy controls (28.5±23.9). The mean polyclonal IgG-IgA anti-CCP3 serum levels were measured as 254.0±169.5 in patients and 3.8±3.6 in healthy individuals. The diagnostic accuracy analysis of salivary IgG-IgA anti-CCP3 results in an area under the curve (AUC) of 0.818, as well as 91.84% specificity and 61.90% sensitivity.
Conclusion: Salivary anti-CCP3 may be considered as an additional screening test for rheumatoid arthritis.
Evaluation of the anti-RANKL monoclonal antibody in rheumatoid arthritis rats
Authors: Lv Dawei , Zhao Xiaodong 
Published: March 2023

Objectives: In this study, we aimed to investigate the therapeutic effect of anti-receptor activator of nuclear factor kappa-κB ligand (RANKL) monoclonal antibodies R748-1-1-1, R748-1-1-2 and R748-1-1-3 on rheumatoid arthritis (RA) in a rat model.
Materials and methods: Gene cloning, hybridoma technology, affinity purification, enzyme-linked immunosorbent assay, general observation, hematoxylin-eosin staining, X-ray, and many other experimental techniques were used in this study.
Results: Improved collagen-induced arthritis (CIA) modeling was successfully constructed. The RANKL gene was cloned and the anti-RANKL monoclonal antibody was prepared. Following treatment with the anti-RANKL monoclonal antibody, the soft tissue swelling of the hind paws, the joint thickening, the narrowed joint gap, and the blurred edge of the bone joint were improved. The pathological changes such as synovial hyperplasia of fibrous tissue, cartilage and bone destruction were significantly decreased in the anti-RANKL monoclonal antibody-treated CIA group. Compared to the normal control group and phosphate buffer saline (PBS)-treated CIA group, the expression of tumor necrosis factor-alpha (TNF-α) and interleukin-1 (IL-1) in antibody-treated CIA group, positive drug-treated CIA group, and IgG-treated CIA group were decreased (p<0.05).
Conclusion: The anti-RANKL monoclonal antibody can promote the therapeutic effect of RA rats, indicating that the anti-RANKL monoclonal antibody has a certain potential value and may be beneficial to the further study of the mechanism of RA treatment.
Application of Elements of Human Resource Management Strategic: Does it Affect the Work Performance of Koperasi Kencana Makmur Lamongan Employees?
Authors: Wahyuningsih Yulie , Suyitno Suyitno 
Published: March 2023

This study aims to describe efforts to improve work performance through the application of
strategic HRM elements and employee performance achievements covering efforts to compl
ete tasks, understanding task perceptions, output quality, output quantity, work time effectiveness,
and career development at the Koperasi Kencana Makmur. Using descriptive and inferential
statistical analysis methods. Descriptive analysis was used to det
ermine respondents' perceptions
of strategic HRM elements and employee performance. Furthermore, relative frequency analysis,
average count and maximum and minimum values of variables, indicators and research items
were carried out, to measure the relation
ship between variables using multiple linear regression
analysis. Aims to explain the influence of strategic HRM elements on work performance. Using
the population of all permanent employees of the Koperasi Kencana Makmur. Sampling using
proportional strat
ified random sampling technique, because the population has elements that are
not homogeneous and proportional stratified, with a sample of 60 respondents. The results of this
study indicate that there are four independent variables, namely: growth and lea
rning of all
personnel (X4), integration with company strategy (X5), owning and developing collaboration
(X8) and the active role of employees in developing the company's business (X9) which have a
significant effect on achievement employee work, while the
other five variables namely:
employees' understanding of external influences (X1), understanding of labor market dynamics
and competition (X2), having a long
-
term focus (X3), having and developing technical
capabilities (X6) and owning and developing conc
eptual ability (X7) has no significant effect on
employee performance. that the variable active role of employees in developing the company's
business has a greater regression coefficient of 0.512 than the regression coefficients of other
variables. It can
be emphasized that the variable active role of employees in developing the
company's business has a dominant and positive influence on employee performance
in the
Koperasi Kencana Makmur.
Electronic Word-Of-Mouth (E-Wom) Model and Consumer Decisions on Pantai Cermin Tourism
Authors: Rivai Ahmad , Amalia Fiqrida , Chaniago Sabaruddin , Martin Martin , Nasib Nasib 
Published: March 2023

The main objectives of this research are to study the factors that influence Electronic Word-Of-Mouth (E-Wom) and consumer decisions and to formulate the Electronic Word-of-Mouth (E-Wom) model and consumer decisions to travel on the beach. Deli Serdang Mirror. This study uses descriptive analysis, both qualitative and quantitative. Data analysis with statistics used is the Structural Equation Modeling (Structural Equation Modeling). Based on the analysis and discussion, it is concluded that there is a significant influence of Service Quality on E-WOM. There is a significant effect of Price on E-WOM. There is a significant effect of Service Quality on Purchase decisions. There is a significant effect of E-WOM on Purchase decisions. There is a significant effect of E-WOM on Purchase decisions. There is a significant influence of Service Quality on Purchase decisions through E-WOM. And there is a significant effect of Price on Purchase decisions through E-WOM
Novel Strategies to Improve CAR-T Cells in Solid Tumors: Mini Review
Authors: Ahmed Manal Mohamed Elsayed 
Published: March 2023

Purpose: The paper reviews the obstacles that face CAR-T cells in solid tumors and the suggested novel strategies to overcome these obstacles in association with the efficacy as well as the safety profile of CAR-T cell therapy.
Subjects and Methods: This is a systematic review exploring the novel strategies to improve CAR-T cells in solid tumors.
Results: Several strategies have been developed, including: 1) targeting multiple antigens; 2) improving trafficking of CAR-T cells into tumor tissues; 3) Preventing the immunosuppression of TME on CAR-T cells by different approaches such as blocking the recruitment of MDSCs or TAM in TME, saving CAR-T cells viability from exhaustion by blocking negative signals, and enhancement of CAR-T cells persistence activity by blocking PD-1/PDL-1 pathway in TME, 4) designing novel CAR-T cells to prevent the exhaustion; and 5) inducing a self T cells response in the tumor-bearing host to prevent tumor escape and enhance CAR-T cells activity.
Conclusions: Recent researches about CAR-T cells therapy carries new hope for targeting solid tumors.