bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sympathetic activity is not a main cause of blood pressure reduction with exercise training in un‐medicated middle‐aged/older men
Authors: Ehlers Thomas S. , Møller Sophie , Hansen Camilla C. , Tamariz‐Ellemann Andrea S. , Vermeulen Tyler D. , Shoemaker J. Kevin , Gliemann Lasse , Hellsten Ylva 
Published: January 2023

BackgroundThis study tested the hypothesis that training reduces resting sympathetic activity and improves baroreflex control in both hypertensive and normotensive men but reduces blood pressure only in hypertensive men.MethodsMiddle‐aged/older un‐medicated stage‐1 hypertensive males (mean age 55 ± 3 years; n = 13) and normotensive controls (mean age 60 ± 5 years; n = 12) participated in 8 weeks of supervised high‐intensity interval spinning training. Before and after training, muscle sympathetic nerve activity (MSNA) and blood pressure were measured at rest and during a sympatho‐excitatory cold pressor test (CPT). Based on the measurements, baroreceptor sensitivity and baroreceptor threshold were calculated.ResultsResting MSNA and baroreceptor sensitivity were similar for the hypertensive and the normotensive groups. Training lowered MSNA (p < 0.05), expressed as burst frequency (burst/min), overall, and to a similar extent, in both groups (17% and 27%, respectively, in hypertensive and normotensive group), whereas blood pressure was only significantly (p < 0.05) lowered (by 4 mmHg in both systolic and diastolic pressure) in the hypertensive group. Training did not (p > 0.05) alter the MSNA or blood pressure response to CPT or increase baroreceptor sensitivity but reduced (p < 0.05) the baroreceptor threshold with a main effect for both groups. Training adherence and intensity were similar in both groups yet absolute maximal oxygen uptake increased by 15% in the normotensive group only.ConclusionThe dissociation between the training induced changes in resting MSNA, lack of change in baroreflex sensitivity and the change in blood pressure, suggests that MSNA is not a main cause of the blood pressure reduction with exercise training in un‐medicated middle‐aged/older men.
First-time revision knee arthroplasty using a hinged prosthesis
Authors: Clement Nick D. , Avery Peter , Mason James , Baker Paul N. , Deehan David J. 
Published: January 2023

Aims The aim of this study was to identify variables associated with time to revision, demographic details associated with revision indication, and type of prosthesis employed, and to describe the survival of hinge knee arthroplasty (HKA) when used for first-time knee revision surgery and factors that were associated with re-revision. Methods Patient demographic details, BMI, American Society of Anesthesiologists (ASA) grade, indication for revision, surgical approach, surgeon grade, implant type (fixed and rotating), time of revision from primary implantation, and re-revision if undertaken were obtained from the National Joint Registry data for England, Wales, Northern Ireland, and the Isle of Man over an 18-year period (2003 to 2021). Results There were 3,855 patient episodes analyzed with a median age of 73 years (interquartile range (IQR) 66 to 80), and the majority were female (n = 2,480, 64.3%). The median time to revision from primary knee arthroplasty was 1,219 days (IQR 579 to 2,422). Younger age (p < 0.001), decreasing ASA grade (p < 0.001), and indications for revision of sepsis (p < 0.001), unexplained pain (p < 0.001), non-polyethylene wear (p < 0.001), and malalignment (p < 0.001) were all associated with an earlier time to revision from primary implantation. The median follow-up was 4.56 years (range 0.00 to 17.52), during which there were 410 re-revisions. The overall unadjusted probability of re-revision for all revision HKAs at one, five, and ten years after surgery were 2.7% (95% confidence interval (CI) 2.2 to 3.3), 10.7% (95% CI 9.6 to 11.9), and 16.2% (95% CI 14.5 to 17.9), respectively. Male sex (p < 0.001), younger age (p < 0.001), revision for septic indications (p < 0.001) or implant fracture (p = 0.010), a fixed hinge (p < 0.001), or surgery performed by a non-consultant grade (p = 0.023) were independently associated with an increased risk of re-revision. Conclusion There were several factors associated with time to first revision. The re-revision rate was 16.2% at ten years; however, the risk factors associated with an increased risk of re-revision could be used to counsel patients regarding their outcome. Cite this article: Bone Joint J 2023;105-B(1):47–55.
A clinical and radiological matched-pair analysis of patients treated with the PRECICE and STRYDE magnetically driven motorized intramedullary lengthening nails
Authors: Vogt Bjoern , Rupp Carolin , Gosheger Georg , Eveslage Maria , Laufer Andrea , Toporowski Gregor , Roedl Robert , Frommer Adrien 
Published: January 2023

AimsDistraction osteogenesis with intramedullary lengthening devices has undergone rapid development in the past decade with implant enhancement. In this first single-centre matched-pair analysis we focus on the comparison of treatment with the PRECICE and STRYDE intramedullary lengthening devices and aim to clarify any clinical and radiological differences.MethodsA single-centre 2:1 matched-pair retrospective analysis of 42 patients treated with the STRYDE and 82 patients treated with the PRECICE nail between May 2013 and November 2020 was conducted. Clinical and lengthening parameters were compared while focusing radiological assessment on osseous alterations related to the nail’s telescopic junction and locking bolts at four different stages.ResultsOsteolysis next to the telescopic junction was observed in 31/48 segments (65%) lengthened with the STRYDE nail before implant removal compared to 1/91 segment (1%) in the PRECICE cohort. In the STRYDE cohort, osteolysis initially increased, but decreased or resolved in almost all lengthened segments (86%) after implant removal. Implant failure was observed in 9/48 STRYDE (19%) and in 8/92 PRECICE nails (9%). Breakage of the distal locking bolts was found in 5/48 STRYDE nails (10%) compared to none in the PRECICE cohort. Treatment-associated pain was generally recorded as mild and found in 30/48 patients (63%) and 39/92 (42%) in the STRYDE and PRECICE cohorts, respectively. Temporary range of motion (ROM) limitations under distraction were registered in 17/48 (35%) segments treated with the STRYDE and 35/92 segments (38%) treated with the PRECICE nail.ConclusionOsteolysis and periosteal reaction, implant breakage, and pain during lengthening and consolidation is more likely in patients treated with the STRYDE nail compared to the PRECICE nail. Temporary ROM limitations during lengthening occurred independent of the applied device. Implant-related osseous alterations seem to remodel after implant removal. Cite this article: Bone Joint J 2023;105-B(1):88–96.
Structurally intact and functionally incompetent foveal triangular fibrocartilage complex injuries
Authors: Crowe Christopher S. , Kakar Sanj 
Published: January 2023

Injury to the triangular fibrocartilage complex (TFCC) may result in ulnar wrist pain with or without instability. One component of the TFCC, the radioulnar ligaments, serve as the primary soft-tissue stabilizer of the distal radioulnar joint (DRUJ). Tears or avulsions of its proximal, foveal attachment are thought to be associated with instability of the DRUJ, most noticed during loaded pronosupination. In the absence of detectable instability, injury of the foveal insertion of the radioulnar ligaments may be overlooked. While advanced imaging techniques such as MRI and radiocarpal arthroscopy are well-suited for diagnosing central and distal TFCC tears, partial and complete foveal tears without instability may be missed without a high degree of suspicion. While technically challenging, DRUJ arthroscopy provides the most accurate method of detecting foveal abnormalities. In this annotation the spectrum of foveal injuries is discussed and a modified classification scheme is proposed. Cite this article: Bone Joint J 2023;105-B(1):5–10.
Clinical effectiveness of the Ganga Hospital Open Injury Severity Score for limb salvage versus amputation in patients with complex limb injuries
Authors: Ndlovu Sebastian , Naqshband Mumraiz , Masunda Stanley , Ndlovu Kudzayi , Chettiar Krissen , Anugraha Anoop 
Published: January 2023

AimsClinical management of open fractures is challenging and frequently requires complex reconstruction procedures. The Gustilo-Anderson classification lacks uniform interpretation, has poor interobserver reliability, and fails to account for injuries to musculotendinous units and bone. The Ganga Hospital Open Injury Severity Score (GHOISS) was designed to address these concerns. The major aim of this review was to ascertain the evidence available on accuracy of the GHOISS in predicting successful limb salvage in patients with mangled limbs.MethodsWe searched electronic data bases including PubMed, CENTRAL, EMBASE, CINAHL, Scopus, and Web of Science to identify studies that employed the GHOISS risk tool in managing complex limb injuries published from April 2006, when the score was introduced, until April 2021. Primary outcome was the measured sensitivity and specificity of the GHOISS risk tool for predicting amputation at a specified threshold score. Secondary outcomes included length of stay, need for plastic surgery, deep infection rate, time to fracture union, and functional outcome measures. Diagnostic test accuracy meta-analysis was performed using a random effects bivariate binomial model.ResultsWe identified 1,304 records, of which six prospective cohort studies and two retrospective cohort studies evaluating a total of 788 patients were deemed eligible for inclusion. A diagnostic test meta-analysis conducted on five cohort studies, with 474 participants, showed that GHOISS at a threshold score of 14 has a pooled sensitivity of 93.4% (95% confidence interval (CI) 78.4 to 98.2) and a specificity of 95% (95% CI 88.7 to 97.9) for predicting primary or secondary amputations in people with complex lower limb injuries.ConclusionGHOISS is highly accurate in predicting success of limb salvage, and can inform management and predict secondary outcomes. However, there is a need for high-quality multicentre trials to confirm these findings and investigate the effectiveness of the score in children, and in predicting secondary amputations. Cite this article: Bone Joint J 2023;105-B(1):21–28.
Microgrid Hybrid Solar/Wind/Diesel and Battery Energy Storage Power Generation System: Application to Koh Samui, Southern Thailand
Authors: Khamharnphol Rawit , Kamdar Ismail , Waewsak Jompob , Chaichan Weerasak , Khunpetch Sakrapee , Chiwamongkhonkarn Somphol , Kongruang Chuleerat , Gagnon Yves 
Published: January 2023

This paper presents the optimization of a 10 MW solar/wind/diesel power generation system with a battery energy storage system (BESS) for one feeder of the distribution system in Koh Samui, an island in southern Thailand. The main objectives are to maximize the deployment of renewable energy-based power generation and to minimize the levelized cost of energy (LCOE). A hybrid renewable energy-based power generation system, consisting of solar PV, wind turbine generators, diesel generator (DiG), bi-directional grid-tied charging inverter (CONV) and BESS, was simulated using HOMER Pro®. This study accessed the database of the National Aeronautics and Space Administration (NASA) for the Surface meteorology and Solar Energy (SSE) for the global solar radiation and temperature, along with the Modern-Era Retrospective analysis for Research and Applications (MERRA-2) wind database. The simulations show that Scenario 1 (PV/Wind/DiG/BESS/CONV) and Scenario 3 (PV/DiG/BESS/CONV) are the optimal configurations regarding the economic indicators (i.e. minimum net present costs (NPC) of 438 M$ and LCOE of 0.20 $/kWh) and the environmental indicators (i.e. lowest greenhouse gases (GHG) emission avoidances of 6,339 tonnes/year and highest renewable fraction (RF) of 89.4%). Furthermore, the sensitivity analysis illustrates that Scenario 3 offers the optimal system type with the largest annual energy production (AEP). Besides contributing to the body of knowledge of optimization methodologies for microgrid hybrid power systems, the outcome of this work will assist the regional energy practitioners and policy makers regarding optimal configurations of microgrid hybrid systems in the development of a Green Island concept for Koh Samui.
Existential threats to pastoralism in an arid environment: the fate of Gujii pastoralists in Southern Ethiopia
Authors: Guye Mekuria Haleke , Legesse Abiyot , Mohammed Yimer 
Published: January 2023

<span lang="EN-GB">The pastoralists of Gujii have faced numerous risks, with their pastoralism system facing serious challenges. With the technically inconsistent and timely unmanaged interventions, several pastoral households are facing unreserved challenges. As a result, the future of pastoralists appears to be in great danger. The objective of this study is to investigate the ongoing challenges of Gujii pastoralism, as well as the fate of pastoralists in southern Ethiopia who are suffering from unrelenting drought. Ethiopian Meteorological Agency provided monthly rainfall and temperature data from 1986 to 2016. A household survey was conducted with 340 household heads randomly chosen from the study area to examine the challenges of the pastoralists have been facing. Moreover, a key informant interview and a focus group discussion were employed to collect qualitative data. Each watershed unit held one round of focus group discussions, with an average of 7-10 participants. The coefficient of variation (CV) was used to detect the temporal variability of seasonal rainfall and temperature. To detect trends, the Mann Kendall (MK) and Sen's slope estimator were used to determine the trends and magnitude of the change. Political and tenure insecurity seriously affected the pastoral system in different ways. Autumn and spring had high variability in rainfall, with CV = 48.76% and 32.43%, respectively. Both winter and spring temperatures show a significant increase at (a = 0.1). Climate variability has made the already fragile pastoral households even more vulnerable. Pastoralist’s future would be difficult with all of these problems, and its resilience would be doubtful. As a result, in order to ensure the pastoral's long-term survivability, the government.</span>
Parámetros biomecánicos de la función del pie medidos en el consultorio del especialista en Ortopedia y Traumatología
Authors: Castellini Jorge 
Published: January 2023

Introducción: Los estudios dinámicos de la función del pie habitualmente se realizan en laboratorios de marcha de gran complejidad. El objetivo de este estudio fue analizar parámetros funcionales utilizando una plataforma de fuerza en una serie de pacientes asintomáticos evaluados en consultorios externos.
Materiales y Métodos: Estudio de corte transversal que incluyó una serie consecutiva de pacientes asintomáticos voluntarios a quienes se les realizó una medición con una plataforma de fuerza (TekScan MatScan®, Boston, MA, EE.UU.) entre 2014 y 2020, en la Ciudad Autónoma de Buenos Aires, Argentina.
Resultados: Se incluyeron 316 registros de 158 pacientes con mediciones bilaterales. La mayoría eran mujeres (66,5%) y el promedio de la edad era de 47 años (DE 16.1). Se evaluaron 14 variables, correspondientes a parámetros de fuerza, trayectoria y tiempo de contacto de la fuerza. El tiempo de contacto total fue de 0,79 segundos (DE 0,09), el CoF time según la región del pie fue del 20% en el talón, 26% en el mediopié y 46% en el antepié. El CPEI (center of pressure excursion index) fue del 16,55% (DE 7,14).
Conclusiones: Se comunican los parámetros funcionales del pie en pacientes asintomáticos. Se midieronel tiempo de contacto del pie en el suelo, la fuerza (en talón, mediopié y antepié) y la trayectoria de la fuerza con una plataforma de fuerza. No se utilizaron radiaciones ionizantes. Estos hallazgos podrían ser utilizados como valores de referencia para detectar marchas patológicas.
Nivel de Evidencia: II
Personas y personajes en transición etno-sociolingüística en el ámbito románico. Algunos ejemplos de los siglos XVIII y XIX
Authors: Alén Garabato Carmen 
Published: January 2023

A partir de finales del siglo XVIII, la instauración de la escolarización obligatoria y el aumento de la movilidad geográfica y social han contribuido a la difusión generalizada de las lenguas oficiales de los Estados, antes solo reservadas a algunos sectores privilegiados. En las comunidades que habían mantenido el uso de otra lengua, esto significa el fin del monolingüismo en un primer momento y luego la aceleración de las dinámicas que en algunos casos llevarán a la desaparición de las lenguas minorizadas.
El cambio de lengua implica un cambio de grupo y de clase social: una transgresión del poder simbólico, que no pasa desapercibida en la literatura de los siglos XVIII y XIX, en la que es frecuente encontrar personajes estereotipados que representan la transición etno-sociolingüística. Se trata de puestas en escena de la diglosia, productos de las ideologías lingüísticas, que no son (solo) simples divertimientos: los autores de las obras que comentaremos, en el ámbito románico, aprovechan el éxito popular de estos personajes para criticar o denunciar determinados comportamientos sociales o políticos.
Analysis and Prediction of Student Performance by Using A Hybrid Optimized BFO-ALO Based Approach
Authors: Kumar Sandeep , Ahuja Bindiya 
Published: January 2023

Data mining offers effective solutions for a variety of industries, including education. Research in the subject of education is expanding rapidly because of thebigquantityof student data that can be utilized to uncover valuable learning behavior patterns. This research presents a method for forecasting the academic presentation of students in Portuguese as well as math subjects, and it is describing with the help of 33 attributes. Forecasting the educationalattainment of students is the most popular field of study in the modern period. Previous research has employed a variety of categorization algorithms to forecast student performance. Educational data mining is a topic that needs a lot of research to improve the precision of the classification technique and predict how well students will do in school. In this study, we made a method to predict how well a student will do that uses a mix of optimization techniques. BFO and ALO-based popular optimization techniques were applied to the data set. Python was used to process all the files and conduct a performance comparison analysis. In this study, we compared our model's performance with various existing baseline models and examined the accuracy with which the hybrid algorithm predicted the student data set. To verify the expected classification accuracy, a calculation was performed. The experiment's findings indicate that the BFO-ALO Based hybrid model, which, out of all the methods, with a 94.5 percent success rate, is the preferred choice.
Postural stability in early Parkinson’s disease: effect of cognitive dual-tasking
Authors: ERDEM Miray , BALAL Mehmet , DEMİRKIRAN Meltem 
Published: January 2023

Purpose: The primary aim of this study is to evaluate postural stability by using a static posturography in patients with early Parkinson’s disease (PD). Secondly, this paper addresses the need for illustrating the effect of dual-tasking on postural stability in early PD patients.
Materials and Methods: Twenty-nine early PD patients with maximum 5 years of disease duration were included in this study. The selected group had no clinical PI while their age- and sex-matched healthy controls were carried out. Neurological examination and mini-mental state examination (MMSE) were performed in all subjects. Unified Parkinson Disease Rating Scale (UPDRS) and modified Hoehn and Yahr (H&Y) scores were recorded in PD patients. Postural stability was assessed in all subjects on a static posturography platform under three different conditions: eyes open, eyes closed and a cognitive task of producing words with given letters.
Results: The mean age of the PD was 59.2±10.5 whereas the control groups mean age was 56.3±7.6 (p>0.05). The female-male ratio was 9/20 in the PD and 12/17 in the control group. There was no important difference between the two groups in terms of demographic characteristics. In the PD group, the mean UPDRS was 12.8±4.9. The patients were mostly receiving polytherapy.
Eye closure and cognitive task caused an increase in most sway parameters in both groups.
Conclusion: Early PD patients on medication, postural stability is preserved and cognitive dual-tasking does not affect postural stability in these patients in the early stage.
Optic disc, macula and ganglion cell layer measurements obtained with optical coherence tomography in patients with thyroid disorder
Authors: KUNT Zeynep , MADEN Gamze , KARATAŞ Mehmet Egemen , MART Gülay 
Published: January 2023

Purpose: The aim of this study was to compare retinal nerve layer thickness, central macula thickness and ganglion cell layer measurements using optical coherence tomography (OCT) between thyroid patients and age- and sex-matched healthy controls.
Materials and Methods: Eighty eyes of 80 patients in the thyroid patient group and 48 eyes of 48 patients in the control group were included in the study. After evaluating the exclusion criteria, visual acuity, anterior segment biomicroscopy, intraocular pressure, fundoscopy and spectral field optic coherence tomography (SF-OCT) imaging tests were performed on all patients included in the study. These data have been recorded. Central macular thickness (CMT), retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) measurements were evaluated by statistical methods for both groups.
Results: There was no statistically significant difference between the demographic data of the groups included in the study. IOP measurements were found to be statistically significantly higher in the patient group compared to the control group. CMT values were 258.2±16.1 µm in the patient group and 273.1±23.8 µm in the control group, and statistically significant differences were observed between the groups.
Conclusion: The findings supports that changes in the optic nerve and macula develop before vision loss in TO patients compared to the healthy control group. We can follow TO patients more objectively and reliably and make treatment planning more accurately by adding OCT, which is a noninvasive test, to our clinical practice, since structural changes develop before functional deterioration in TO patients.