bluuebunny/crossref_metadata_2025_split huggingface dataset:
Estrogen and testosterone supplementation improves tendon healing and functional recovery after rotator cuff repair
Authors: Tashjian Robert Z. , Zitnay Jared , Kazmers Nikolas H. , Veerabhadraiah Shivakumar R. , Zelada Antonio C. , Honeggar Matthew , Chalmers Peter N. , Henninger Heath B. , Jurynec Michael J. 
Published: September 2023

AbstractFailure of healing after rotator cuff repair (RCR) is common. The purpose of the current study was to evaluate the effect of systemic estrogen or testosterone supplementation on tendon healing after RCR. Seventy‐two adult male mice were utilized for all experiments. The supraspinatus tendon was transected and repaired with 6‐0 Prolene suture on the left shoulder of 51 animals. Mice were segregated into three groups postoperative: (1) vehicle group (VG; n = 18), (2) estrogen group (EST; n = 17), and (3) testosterone group (TST; n = 16). An unrepaired control group (unrepaired, n = 21) did not have surgery. Utilizing these animals, histological analysis, activity testing, biomechanical testing and RNA sequencing (RNA‐seq) was performed. At 8 weeks post‐RCR, TST, and EST supplementation improved the overall histologic structure of the repaired enthesis site. No differences in ultimate failure loads or stiffness were detected between VG, EST, and TST groups after biomechanical testing. RCR caused a reduction in wheel activity compared to unrepaired controls and supplementation with TST restored wheel activity. RNA‐seq analysis indicated that estrogen and testosterone regulated different pathways associated with enthesis healing, including a suppression of inflammatory signaling. Supplementation with sex hormones improved the structure of the repaired tendon enthesis and significantly regulated expression of diverse pathways regulating multiple biological processes. Testosterone administration following RCR restored wheel activity without having a detrimental impact on biomechanical strength. Future human studies of sex hormone supplementation after RCR are warranted as supplementation in an animal model may improve tendon enthesis healing.
Raman identification of pigments and opacifiers: Interest and limitation of multivariate analysis by comparison with solid state spectroscopical approach—I. Lead‐tin and Naples Yellow
Authors: Burlot Jacques , Vangu Divine , Bellot‐Gurlet Ludovic , Colomban Philippe 
Published: September 2023

AbstractLead‐tin/Naples Yellow provides a bright yellow color often used in combination with a blue‐colored glass to obtain a variety of green hues to decorate enameled glass, metalware, and ceramics. From the analysis of about hundreds of enameled objects from French and Chinese productions of the 18th century, we identify and compare the Raman signatures representative of these yellow pigments. For the first time, we propose several procedures that allow us to compare our data with those obtained from the literature on the spectra of synthesized pigments also characterized by XRD. A first approach is a reasoned analysis of the parameters obtained from the spectral decomposition carried out on spectra visually selected as the most different and the “purest.” A second approach uses multivariate analyses with principal component analysis (PCA) or hierarchical clustering of the spectra and of the band parameters originating from a spectral decomposition. It appears that the precise identification of the phase from simple observation of the sole Raman signature may be unreliable when only main peaks are detected due to the large non‐stoichiometry of the phases and the resulting similarity of the Raman signatures. PCA analysis of the total Raman spectra does not allow relevant classifications due to the strong contributions induced by the bands of the silicate matrix. However, the combination of a reasoned analysis of the Raman spectra with the PCA of spectroscopic parameters extracted from Raman spectral decomposition appears effective in categorizing the different pigments. From the results discussed, at least three types of Raman signatures are identified for each Sn‐ and Sb‐based pigment and correlate with the type, the period, and the location of enamel production.
Improvement of the Mathematical Model for Quality Assurance in the Determination of Kinetic Parameters of Thermal Degradation of Polypropylene Through Thermogravimetric Analysis
Authors: Fregoso‐Israel Esteban , Olvera‐Treviño Ángeles , Romero‐Hernández Juan Enrique , Hernández‐Segura Gerardo Omar , Álvarez‐Maciel Carlos 
Published: September 2023

AbstractRobust mathematical treatment of the Ozawa/Flynn/Wall isoconversion method is conducted to determine the value and uncertainty of the activation energy and pre‐exponential factor for the degradation of polypropylene in thermogravimetric analysis experiments at constant heating rates. The present work employs mathematical models and uncertainty propagation techniques based on the Guide to the Expression of Uncertainty in Measurement to estimate the Arrhenius activation energy and pre‐exponential factor due to the uncertainty of the integration constant b, both in a linear and a third‐degree reciprocal polynomial model with respect to x. The error arising from Doyle's linear approximation in the improper integral of temperature in the Arrhenius equation is examined, and an alternative method is proposed to correct this error, reducing it to 0.032% in the working interval of −200 ≤ x ≤ −15, where x = −E/RT. Given the increased sensitivity of modern thermogravimetric analysis equipment, these improvements are considered essential for obtaining reliable results that align with experimental precision limits compared to previous works. Thus, this allows for the development of an enhanced quality assurance framework by providing more robust uncertainty estimation and a better understanding of the method. Moreover, this approach can be applied to other similar polymer system.
Verification of satellite and model products against a dense rain gauge network for a severe flooding event in Kumasi, Ghana
Authors: Agyekum Jacob , Amekudzi Leonard K. , Stein Thorwald , Aryee Jeffrey N. A. , Atiah Winifred Ayinpogbilla , Adefisan Elijah Adesanya , Danuor Sylvester K. 
Published: September 2023

AbstractFloods as a result of severe storms cause significant impacts on lives and properties. Therefore, timely and accurate forecasts of the storms will reduce the associated risks. In this study, we look at the characteristics of a storm on 28 June, 2018 in Kumasi from a rain gauge network and satellite data, and reanalysis data. The storm claimed at least 8 lives and displaced 293 people in Kumasi, Ghana. The ability of satellite and reanalysis data to capture the temporal variations of the storm was assessed using a high temporal resolution (accumulation per minute) rain gauge data. We employed the observation data from the Dynamics–Aerosol–Chemistry–Cloud Interactions in West Africa (DACCIWA) rain gauges to assess the storm's onset, duration, and cessation. Subsequently, the performance of the ERA5 reanalysis and Global Precipitation Measurement (GPM) satellite precipitation estimates in capturing the rainfall is assessed. Both GPM and the ERA5 had difficulty reproducing the hourly pattern of the rain. However, the GPM produced variability that is similar to the observed. Generally, the region of maximum rainfall was located in the southern parts of the study domain in ERA5, while GPM placed it in the northern parts. The study contributes a verification measure to improve weather forecasting in Ghana as part of the objectives of the GCRF African Science for Weather Information and Forecasting Techniques (SWIFT) project.
Whole knee joint mapping using a phase modulated UTE adiabatic T1ρ (PM‐UTE‐AdiabT1ρ) sequence
Authors: Ma Yajun , Carl Michael , Tang Qingbo , Moazamian Dina , Athertya Jiyo S. , Jang Hyungseok , Bukata Susan V. , Chung Christine B. , Chang Eric Y. , Du Jiang 
Published: September 2023

AbstractPurposeTo develop a 3D phase modulated UTE adiabatic T1ρ (PM‐UTE‐AdiabT1ρ) sequence for whole knee joint mapping on a clinical 3 T scanner.MethodsThis new sequence includes six major features: (1) a magnetization reset module, (2) a train of adiabatic full passage pulses for spin locking, (3) a phase modulation scheme (i.e., RF cycling pair), (4) a fat saturation module, (5) a variable flip angle scheme, and (6) a 3D UTE Cones sequence for data acquisition. A simple exponential fitting was used for T1ρ quantification. Phantom studies were performed to investigate PM‐UTE‐AdiabT1ρ's sensitivity to compositional changes and reproducibility as well as its correlation with continuous wave–T1ρ measurement. The PM‐UTE‐AdiabT1ρ technique was then applied to five ex vivo and five in vivo normal knees to measure T1ρ values of femoral cartilage, meniscus, posterior cruciate ligament, anterior cruciate ligament, patellar tendon, and muscle.ResultsThe phantom study demonstrated PM‐UTE‐AdiabT1ρ's high sensitivity to compositional changes, its high reproducibility, and its strong linear correlation with continuous wave–T1ρ measurement. The ex vivo and in vivo knee studies demonstrated average T1ρ values of 105.6 ± 8.4 and 77.9 ± 3.9 ms for the femoral cartilage, 39.2 ± 5.1 and 30.1 ± 2.2 ms for the meniscus, 51.6 ± 5.3 and 29.2 ± 2.4 ms for the posterior cruciate ligament, 79.0 ± 9.3 and 52.0 ± 3.1 ms for the anterior cruciate ligament, 19.8 ± 4.5 and 17.0 ± 1.8 ms for the patellar tendon, and 91.1 ± 8.8 and 57.6 ± 2.8 ms for the muscle, respectively.ConclusionThe 3D PM‐UTE‐AdiabT1ρ sequence allows volumetric T1ρ assessment for both short and long T2 tissues in the knee joint on a clinical 3 T scanner.
Numerical multi‐span segmented trapdoor test with viscoelastic boundary for soil arching within pile‐supported embankment under cyclic loading
Authors: Zhou Jie , Zhang Ling , Zhou Shuai , Lin Wei , Chen Yun‐Hao , Zhao Ming‐Hua 
Published: September 2023

AbstractDynamic wave reflections would interfere with the laboratory observation of the soil arching under cyclic loading when a traditional trapdoor model with rigid boundaries was used. This problem would be prominent when investigating the soil arching in pile‐supported embankments where the stationary support (pile) would be small, making the rigid boundary close to the domain of interest affected by dynamic loads. To avoid dynamic wave reflections and narrow the calculation domain, soil arching within a pile‐supported embankment under cyclic loading is numerically investigated in a multi‐span segmented trapdoor model with flexible boundaries by the particle flow code (PFC). In addition, a pavement structure is included and the springs supporting the trapdoor follow a bi‐linear constitutive model. The energy‐absorbing flexible boundary at the bottom weakens the dynamic wave reflections and is in favor of passing vertical dynamic waves to compact the fill and weaken the influence of cyclic loading on the soil arching effect during the loading stage. Lateral flexible boundaries would facilitate realistically reproducing the effect of cyclic loading on the soil arching because they could consider the weakening of the plugging effect that occurs during the lateral expansion. The development of soil arches of mid‐span and side‐span are different when the load applied at the mid‐span is laterally transferred to adjacent spans by the arching effect.
Factors influencing the burnout dimensions among nurses: A cross‐sectional study in South Korea
Authors: Cha Chiyoung , Baek Gumhee 
Published: September 2023

AbstractAimTo investigate the factors influencing three dimensions of burnout among clinical nurses in South Korea.DesignDescriptive, correlational and cross‐sectional study.MethodsWe recruited 300 clinical nurses to participate in an online survey conducted in June 2021. Purposive sampling was used for the survey. Multiple linear regression was used for data analysis.ResultsThe regression models explained 55.8%, 45.8% and 34.3% variances in emotional exhaustion, depersonalization and personal accomplishment respectively. Emotional exhaustion was influenced by experience in the current department, working overtime, shift type, depression, job stress and emotional labour. Depersonalization was influenced by gender, hospital size, the associated department, overtime, coping strategies, depression and emotional labour. Personal accomplishment was influenced by clinical experience, shift type, resilience and the perceived threat of coronavirus disease 2019.
Evaluation of the elastic field in phase‐field crystal simulations
Authors: Punke Maik , Skogvoll Vidar , Salvalaglio Marco 
Published: September 2023

AbstractThe phase‐field crystal model (PFC) describes crystal structures at diffusive timescales through a periodic order parameter representing the atomic density. One of its main features is that it naturally incorporates elastic and plastic deformation. To correctly interpret numerical simulation results or devise extensions related to the elasticity description, it is important to have direct access to the elastic field. In this work, we discuss its evaluation in classical PFC models based on the Swift–Hohenberg energy functional. We consider approaches where the stress field can be derived from the microscopic density field (i.e., the order parameter) and a simple novel numerical routine is proposed. By numerical simulations, we demonstrate that it overcomes some limitations of currently used methods. Moreover, we shed light on the elasticity description conveyed by classical PFC models, characterizing a residual stress effect present at equilibrium. We show explicitly and discuss the evaluation of the elastic fields in prototypical representative cases involving an elastic inclusion, a grain boundary, and dislocations.
Multigenerational differences in harvesting and use of wild edible fruits and nuts in the South Caucasus
Authors: Faruk Aisyah , Nersesyan Anush , Papikyan Astghik , Galstyan Sona , Hakobyan Emma , Barblishvili Tinatin , Mikatadze‐Pantsulaia Tsira , Darchidze Tamaz , Kuchukhidze Marina , Kereselidze Nona , Kikodze David , Willey Ian , Ryan Philippa , Breman Elinor 
Published: September 2023

Societal Impact StatementEcosystem services are underpinned by biodiversity, which is rapidly eroding globally, threatening rural livelihoods and culture. Examining the uses of wild edible plants (WEPs) that are important to rural communities gives insight into the value of a biodiverse landscape to local communities. Here, the importance of considering age groups in future ethnobotanical and conservation studies is highlighted, as this can enhance our understanding on the dependence of use within a landscape, informing more inclusive conservation actions.SummaryWild edible plants (WEP) remain an important aspect of many rural communities across the world, yet the decline in the diversity and knowledge of WEP use is becoming a global concern. In the Biodiversity Hotspot of the Caucasus, there is few cross‐cultural and multigenerational comparisons of plant uses, limiting our knowledge of resource use and dependence within biodiverse landscapes.Here, we investigate the patterns of use for wild edible fruits and nuts in the South Caucasus, focusing on multigenerational differences in harvesting patterns, diversity and use through semi‐structured interviews in Armenia and Georgia. We calculated use values (UV) for each genera harvested and compared the diversity of genera used between age groups. Pearson chi‐square was used to explore the relationship between age‐groups and genera harvested.We found 53% of rural population (n = 220) actively harvest from wild populations, with older age groups harvesting the highest diversity of plants. Twenty‐four species from 16 genera are harvested, withBerberis vulgarisL. andRosa caninaL. shared between both communities. The association between age and diversity of harvested genera was significant (χ2[48,N= 506]= 114.75,p < .01), mainly driven by a strong positive association withBerberisspp. L.,Crataegusspp. L. andRibesspp. L. with the under 18s andPrunusspp. L. with under 35s. Young harvesters used WEP for income generation, while medicinal use increases across older age groups.Foraging activities within South Caucasus' communities remains active; however, the use of WEP is not uniform within and across different communities.
Recent Advances in Flexible CNC‐Based Chiral Nematic Film Materials
Authors: Zou Xuyang , Xue Rui , An Zewei , Li Hongwei , Zhang Jiale , Jiang Yan , Huang Lijie , Wu Wei , Wang Shuangfei , Hu Guo‐Hua , Li Robert K.Y. , Zhao Hui 
Published: September 2023

AbstractCellulose nanocrystal (CNC) is a renewable resource derived from lignocellulosic materials, known for its optical permeability, biocompatibility, and unique self‐assembly properties. Recent years have seen great progresses in cellulose nanocrystal‐based chiral photonic materials. However, due to its inherent brittleness, cellulose nanocrystal shows limitations in the fields of flexible materials, optical sensors and food freshness testing. In order to solve the above limitations, attempts have been made to improve the flexibility of cellulose nanocrystal materials without destroying their structural color. Despite these progresses, a systematic review on them is lacking. This review aims to fill this gap by providing an overview of the main strategies and the latest research findings on the flexibilization of cellulose nanocrystal‐based chiral nematic film materials (FCNM). Specifically, typical substances and methods used for their preparation are summarized. Moreover, different kinds of cellulose nanocrystal‐based composites are compared in terms of flexibility. Finally, potential applications and future challenges of flexible cellulose nanocrystal‐based chiral nematic materials are discussed, inspiring further research in this field.
Antimicrobial Hydrogels: Potential Materials for Medical Application
Authors: Li Yanni , Han Yujia , Li Hongxia , Niu Xiaohui , Zhang Deyi , Wang Kunjie 
Published: September 2023

AbstractMicrobial infections based on drug‐resistant pathogenic organisms following surgery or trauma and uncontrolled bleeding are the main causes of increased mortality from trauma worldwide. The prevalence of drug‐resistant pathogens has led to a significant increase in medical costs and poses a great threat to the normal life of people. This is an important issue in the field of biomedicine, and the emergence of new antimicrobial materials hydrogels holds great promise for solving this problem. Hydrogel is an important material with good biocompatibility, water absorption, oxygen permeability, adhesion, degradation, self‐healing, corrosion resistance, and controlled release of drugs as well as structural diversity. Bacteria‐disturbing hydrogels have important applications in the direction of surgical treatment, wound dressing, medical device coating, and tissue engineering. This paper reviews the classification of antimicrobial hydrogels, the current status of research, and the potential of antimicrobial hydrogels for one application in biomedicine, and analyzes the current research of hydrogels in biomedical applications from five aspects: metal‐loaded hydrogels, drug‐loaded hydrogels, carbon‐material‐loaded hydrogels, hydrogels with fixed antimicrobial activity and biological antimicrobial hydrogels, and provides an outlook on the high antimicrobial activity, biodegradability, biocompatibility, injectability, clinical applicability and future development prospects of hydrogels in this field.
2D MXenes Nanosheets for Advanced Energy Conversion and Storage Devices: Recent Advances and Future Prospects
Authors: Mateen Abdul , Suneetha Maduru , Ahmad Shah Syed Shoaib , Usman Muhammad , Ahmad Tauqeer , Hussain Iftikhar , Khan Shaukat , Assiri Mohammed A. , Hassan Ahmed M. , Javed Muhammad Sufyan , Han Sung Soo , Althomali Raed H. , Rahman Mohammed M. 
Published: September 2023

AbstractSince the initial MXenes were discovered in 2011, several MXene compositions constructed using combinations of various transition metals have been developed. MXenes are ideal candidates for different applications in energy conversion and storage, because of their unique and interesting characteristics, which included good electrical conductivity, hydrophilicity, and simplicity of large‐scale synthesis. Herein, we study the current developments in two‐dimensional (2D) MXene nanosheets for energy storage and conversion technologies. First, we discuss the introduction to energy storage and conversion devices. Later, we emphasized on 2D MXenes and some specific properties of MXenes. Subsequently, research advances in MXene‐based electrode materials for energy storage such as supercapacitors and rechargeable batteries is summarized. We provide the relevant energy storage processes, common challenges, and potential approaches to an acceptable solution for 2D MXene‐based energy storage. In addition, recent advances for MXenes used in energy conversion devices like solar cells, fuel cells and catalysis is also summarized. Finally, the future prospective of growing MXene‐based energy conversion and storage are highlighted.
A review of frequently used Kampo prescriptions. Part 3. Yokukansan
Authors: Yamaguchi Hideaki , Yoshino Tetsuhiro , Oizumi Hiroaki , Arita Ryutaro , Nogami Tatsuya , Takayama Shin 
Published: September 2023

AbstractBackgroundThe source of yokukansan (YKS) is thought to be Baoying‐Jinjiang (Hoeikinkyōroku in Japanese) by Xue Ji. YKS was originally designed for children and indicated for spasms, clenching of teeth, digestive dysfunction due to mental instability, and insomnia.Key FindingsYKS formula consists of seven types of crude drugs. Clinical studies have revealed that YKS exerts physiological effects including the treatment of behavioral and psychiatric symptoms of dementia (BPSD), preoperative sedation and anxiety, and postoperative delirium. A meta‐analysis showed that YKS could improve BPSD and daily living activities; however, no improvement in cognitive function was observed. Preclinical studies have also reported that YKS modulates neuronal pathways in the central nervous system, including the serotonergic, glutamatergic, GABAergic, and other neurotransmitter pathways. The incidence of adverse events associated with YKS was 5.17%, with the major adverse effect being pseudoaldosteronism. Routine blood sampling is considered for hypokalemia prevention.ConclusionYKS is useful for BPSD and perioperative mental instability. The modulation of the serotonergic and glutamatergic neural pathways is one of mechanisms. Pseudoaldosteronism is one of the side effects.
Renal clearable magnetic nanoparticles for magnetic resonance imaging and guided therapy
Authors: Zhang Qinpeng , Yin Rui , Guan Guoqiang , Liu Huiyi , Song Guosheng 
Published: September 2023

AbstractMagnetic resonance imaging (MRI) is a non‐invasive, radiation‐free imaging technique widely used for disease detection and therapeutic evaluation due to its infinite penetration depth. Magnetic nanoparticles (MNPs) have unique magnetic and physicochemical properties, making them ideal as contrast agents for MRI. However, the in vivo toxicity of MNPs, resulting from metal ion leakage and long‐term accumulation in the reticuloendothelial system (RES), limits their clinical application. To overcome these challenges, there is considerable interest in the development of renal‐clearable MNPs that can be completely cleared through the kidney, reducing retention time and potential toxic risks. In this review, we provide an overview of recent advancements in the development of renal‐clearable MNPs for disease imaging and treatment. We discuss the factors influencing renal clearance, summarize the types of renal‐clearable MNPs, their synthesis methods, and biomedical applications. This review aims to offer comprehensive information for the design and clinical translation of renal‐clearable MNPs.This article is categorized under:
Nanotechnology Approaches to Biology > Nanoscale Systems in Biology
Diagnostic Tools > Biosensing