bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Correlation Between the Type of Fluid Administration and the Incidence of Hypotension in Patients Undergoing Spinal Anesthesia at RS Wijayakusuma Purwokerto
Authors: Taufiqurrahman Sauqi , Cing Marta Tania Gabriel Ching 
Published: January 2025

Background: Spinal anesthesia is a type of regional anesthesia that involves injecting a local anesthetic into the subarachnoid area. The effect of sympathetic blockade in spinal anesthesia can cause dilation of blood vessels, suppress systemic vascular resistance and result in hypotension [1]. The effects of hypotension are pulmonary aspiration, cardiac arrest, respiratory depression, and loss of consciousness. A sudden drop in blood pressure can also cause a heart attack, a complication of spinal anesthesia. Method: A quantitative approach using a correlational observational design with research variables, namely the administration of fluid types with the incidence of hypotension in patients undergoing spinal anesthesia. The research was conducted in the IBS room at Wijayakusuma Hospital, Purwokerto, with samples was calculated obtained 53 respondents who were selected using a purposive sampling technique. The relationship between the two variables tested was carried out using the non-parametric chi square statistical test with the Fisher exact test Results: Among the respondents, the type of fluid administered was crystalloids in 98.1% of cases, with 70.2% of respondents not experiencing hypotension. The chi-square test yielded a p-value of 1.000, indicating no significant correlation between the type of fluid administered and the incidence of hypotension in patients undergoing spinal anesthesia. Conclusion: There is no significant correlation between the administration of crystalloid or colloid fluids and the incidence of hypotension in patients undergoing spinal anesthesia at RST Wijayakusuma Purwokerto.
Level of Intention on Blood Donation Among NEUST Community: A Basis for Blood Type Repository
Authors: Reguyal June Christian G. , Baguio Hazel Mae F. , Alfonso Katherine R. , Astelero Kyla Ivy B. , Abella Aaron Miguel C. , Balcos Pamela O. 
Published: January 2025

Blood is a fluid that travels to all areas of the body that pumped by the heart as well as oxygen, nutrients, and waste materials away from the cells. Therefore, the demand for human blood is high and, having a steady and varied blood supply is still challenging. Blood donation plays a crucial role in maintaining public health, guaranteeing sufficient resources. However, recognizing the distribution of different blood types within a community is imperative for successful donation initiatives.With the help of this study, the Nueva Ecija University of Science and Technology (NEUST) community will have a comprehensive blood type database, which will serve as a basis for future blood type repository aimed at enhancing community resilience and improving the health of those in need of transfusions. It also emphasizes the significance of awareness and intention in encouraging blood donation. By addressing misconceptions and barriers, future initiatives can effectively engage the NEUST community. The result of the study showed that approximately of NEUST Community were aware of their blood type and blood donation. Furthermore, the level of their intention and knowledge demonstrated by respondents regarding their blood type and the importance of blood donation enables the researchers to establish a comprehensive blood repository. Level of Intention on Blood Donation Among NEUST Community: A Basis for Blood Type Repository serves as a vital resource for potential donors and recipients within the NEUST community, facilitating timely and efficient blood transfusion services when needed.
Кадровый вопрос: кризис или окно возможностей?
Authors: Денисова И.А. , Карцева М.А. 
Published: January 2025

В работе обсуждается кадровая ситуация, сложившаяся в настоящее время на российских предприятиях. Всегда ли дефицит кадров и рост заработных плат — негативное явление для экономики? Происходящее удорожание труда как фактора производства способно стать окном возможностей, подталкивающим предприятия к переходу к технологическим улучшениям, сопровождающимся ростом совокупной производительности факторов. Эмпирический анализ на основе свежих микроданных опроса российских предприятий показывает, что существенная часть предприятий расширяет свою деятельность в условиях роста относительной цены труда, что поддерживает наше предположение о существовании окна возможностей.
The paper discusses the labor shortage and wage costs increase reported by the Russian enterprises. Is a personnel shortage and wage growth always a negative sign for the economy? The ongoing rise in the cost of labor can become a window of opportunity, pushing enterprises to improve technology and increase total factor productivity. The empirical analysis based on the late microdata from a survey of Russian enterprises shows that a significant portion of enterprises are expanding under the current increase in the relative price of labor, which prompts for the existence of a window of opportunity. Keywords: labor market, vacancies, labor shortage, Russia.
Pengaruh Komunikasi dan K3 (Keselamatan dan Kesehatan Kerja) terhadap Kinerja Karyawan pada Apartemen Ambassade Residences di Jakarta Selatan
Authors: Novianti Nita , Gandung Muhammad 
Published: January 2025

Penelitian ini bertujuan untuk mengetahui pengaruh komunikasi dan K3 (Keselamatan dan Kesehatan Kerja) terhadap kinerja karyawan pada Apartemen Ambassade Residences di Jakarta selatan. Metode yang digunakan dalam penelitian ini yaitu metode penelitian kuantitatif dengan pendekatan asosiatif. Jumlah populasi karyawan di Apartemen Ambassade Residences sebanyak 60 orang. Pengambilan sampel dilakukan dengan teknik sampling jenuh, dengan jumlah responden sebanyak 60 orang. Teknik analisis data yang digunakan yaitu uji validitas, uji reabilitas, uji asumsi klasik, analisis regresi, uji koefisien korelasi, uji koefisien determinasi dan uji hipotesis dengan menggunakan progam aplikasi SPSS versi 26. Bedasarkan hasil persamaan regresi linear berganda yaitu Y= 10,513 + 0,447 (X1) + 0,299 (X2). Koefisien korelasi secara simultan menunjukkan nilai sebesar 0,653 yang artinya pada variabel komunikasi dan variabel K3 memiliki hubungan yang kuat terhadap variabel kinerja karyawan. Koefisien determinasi secara simultan menunjukan nilai sebesar 0,427. Artinya pengaruh komunikasi dan K3 terhadap kinerja karyawan sebesar 42,7%. Komunikasi berpengaruh signifikan terhadap kinerja karyawan dengan nilai thitung 5,702 > ttabel 2,002 dengan nilai signifikansi 0,000 < 0,05. K3 berpengaruh signifikan terhadap kinerja karyawan dengan nilai thitung 5,365 > ttabel 2,002 dengan nilai signifikansi 0,000 < 0,05. Bedasarkan hasil uji f dapat diketahui bahwa fhitung 21,208 > ftabel 3,160 dan nilai signifikansi 0,000 < 0,05. Artinya secara simultan variabel komunikasi dan K3 berpengaruh signifikan terhadap kinerja karyawan.
Diminished ovarian reserve is associated to euploidy rate: a single center study
Authors: Carnesi Edoardo , Castellano Stefano , Albani Elena , Busnelli Andrea , Smeraldi Antonella , Bulbul Ozgur , Morenghi Emanuela , Immediata Valentina , Levi-Setti Paolo Emanuele 
Published: January 2025

BackgroundReproductive success shows a well-documented decline with advancing maternal age, primarily due to chromosomal abnormalities (aneuploidies) in embryos. While ovarian reserve markers such as Anti-Müllerian Hormone (AMH) and Antral Follicle Count (AFC) traditionally serve as quantitative predictors of fertility, emerging evidence suggests they may also reflect oocyte quality, particularly in patients with Diminished Ovarian Reserve (DOR). The relationship between these biomarkers and embryo chromosomal status remains complex and poorly understood.MethodsWe conducted a retrospective analysis of in vitro fertilization (IVF) cycles performed between 2015 and 2022, involving 773 female patients who underwent IVF and pre-implantation genetic screening for aneuploidy (PGT-A). Our patient cohort was divided into two groups: Group 1, consisting of women who achieved at least one euploid embryo, and Group 2, comprising women who did not.ResultsThe main outcome measures included the rate and number of euploid blastocysts and their correlation with ovarian reserve. Our results showed a statistically significant association between independent variables and embryo ploidy: AMH levels (OR 1.09; 95% CI 1.04-1.14, p&lt;0.001), the age of the woman (OR 0.82; 95% CI 0.79-0.85, p&lt;0.001), the number of oocytes retrieved (OR 1.050; 95% CI 1.01-1.08, p=0.05), and the fertilization rate (OR 6.69; 95% CI 2.67-16.77, p&lt;0.001).ConclusionOur findings suggest that AMH levels are associated with embryo ploidy rate. These insights could enhance counseling practices in assisted reproductive technology (ART), offering patients a more detailed understanding of their infertility prognosis and the factors influencing IVF outcomes.
Prokaryotic communities associated with marine hydrothermal systems of the Gulf of California
Authors: Aguila-Ramírez Ruth Noemí , González-Acosta Bárbara , Gutiérrez-Almada Karla María , Borges-Souza José Manuel , Cervantes-Gámez Rocío Guadalupe , Quiróz-Guzmán Eduardo 
Published: January 2025

IntroductionMarine hydrothermal systems (MHS) are considered extreme environments due to their unique physicochemical conditions, which are challenging for most organisms. This study investigates the microbial communities in three MHS sites in Baja California Sur, Mexico.MethodsSediment samples were collected in two seasons of the year: rainy and dry season. Bacterial DNA was extracted, the V3-V4 regions of the 16S rRNA gene were amplified.Results and discussionThe analysis of microbial community structure and composition revealed that species richness and diversity were higher at control sites (not influenced by hydrothermal conditions). Samples from the MHS showed temporal variation in richness, as measured by the Chao1 index. Alphaproteobacteria and Gammaproteobacteria were the dominant classes. No significant differences in community structure were found between the seasons or between the control and MHS sites. However, the analysis did reveal differences in community structure among the three hydrothermal locations: Burro, Santispac, and Agua Caliente. The presence of Gammaproteobacteria, Alphaproteobacteria, Deltaproteobacteria, and Betaproteobacteria highlights their key roles in primary production within shallow hydrothermal systems, these microbial communities demonstrate their capacity to colonize diverse substrates. This study enhances the microbiological understanding of hydrothermal environments in Baja California Sur, and molecular analysis of unculturable microbes could provide further insights into their physiology and ecological roles in shallow hydrothermal systems.
Spinal neuromodulation using ultra low frequency waveform inhibits sensory signaling to the thalamus and preferentially reduces aberrant firing of thalamic neurons in a model of neuropathic pain
Authors: Jones Martyn G. , Matthews Liam A. , Lempka Scott , Verma Nishant , Harris James P. , McMahon Stephen B. 
Published: January 2025

IntroductionMany forms of chronic pain remain refractory to existing pharmacotherapies and electrical neuromodulation. We have recently reported the clinical efficacy of a novel form of analgesic electrical neuromodulation that uses ultra low frequency (ULF™) biphasic current and studied its effects on sensory nerve fibers. Here, we show that in anesthetized rats, epidural ULF current reversibly inhibits activation of neurons in the thalamus receiving sensory spinothalamic input.MethodsIn naïve, neuropathic and sham-operated rats, recordings of ongoing and evoked activity were made from thalamic neurons, targeting the ventral posterolateral (VPL) nucleus.ResultsResponses to electrical stimulation of hind limb receptive fields were reduced in 25 of 32 (78%) neurons tested with lumbar epidural ULF neuromodulation. Cells preferentially responsive to low intensity stimulation were more likely to be found than cells responding to a range of stimulus intensities, or high intensity only; and low threshold responses were more likely to be inhibited by ULF than high threshold responses. On-going activity unrelated to hindlimb stimulation, observed in 17 of 39 neurons in naïve animals (44%), was reduced by lumbar epidural ULF current in only 3 of 14 (21%) neurons tested with ULF. By contrast, in rats with a well-characterized neuropathic injury, spinal nerve ligation (SNL), we found a much higher incidence of on-going activity in thalamic neurons: 53 of 55 neurons (96%) displayed firing unrelated to hindlimb stimulation. In this group, ULF current reduced thalamic neurone discharge rate in 19 of 29 (66%) neurons tested. In sham-operated animals, the incidence of such activity in thalamic neurons and the effect of ULF current were not significantly different from the naïve group.DiscussionWe conclude firstly that ULF current can acutely and reversibly interrupt signaling between sensory afferent fibers and relay neurons of the thalamus. Second, ongoing activity of thalamic neurons increases dramatically in the early stages following neuropathic injury. Third, this novel form of neuromodulation preferentially attenuates pathological thalamic activity in this neuropathic model compared to normal activity in naïve and sham-operated animals. This study, therefore, demonstrates that epidural ULF current can reduce nerve injury-related abnormal activity reaching the brain. These findings help advance understanding of possible mechanisms for the analgesic effects of ULF neuromodulation.
Prognostic significance of lymph node ratio in esophageal squamous cell carcinoma: insights from the South Asian population
Authors: Qureshi Sajida , Abbasi Waqas Ahmad , Jalil Hira Abdul , Mughal Saba , Quraishy Muhammad Saeed 
Published: January 2025

BackgroundEsophageal cancer (EC) is a significant health concern in South Asia, yet data on prognostic factors, such as lymph node ratio (LNR), in this region is limited. This study aims to assess the prognostic significance of LNR in esophageal squamous cell carcinoma (ESCC) patients undergoing concurrent neoadjuvant therapy followed by minimally invasive esophagectomy (MIE).MethodsThis retrospective study analyzed the clinical data of ESCC patients who underwent concurrent neoadjuvant therapy followed by MIE at Dr. Ruth K. M. Pfau Civil Hospital from 2019 to 2023. Lymph node ratios were derived and patients were categorized into three groups: LNR 0, LNR low (≤ 0.1), and LNR high (&gt;0.1). Patient characteristics were compared along with lymph node groups, and survival outcomes were analyzed using the Kruskal Wallis and Chi-square/Fisher exact test, Pearson correlation, Kaplan-Meier (KM) estimates, and Cox regression models.ResultsAmong the 47 patients, 15 (31.9%) deaths were observed. Patients with a high LNR had a higher mortality rate (70%) compared to those with a low LNR (41.7%) and 0 LNR (12%) (p = 0.002). Additionally, patients with a high LNR (&gt;0.1) were associated with poorer overall survival (OS) (30.0% vs. 58.3% vs. 88.0%, p &lt; 0.001). A significant correlation was also observed between LNR and the number of metastatic lymph nodes (correlation coefficient = 0.928, p &lt; 0.001).ConclusionOur findings demonstrate that high LNR emerged as an independent prognostic factor in ESCC patients undergoing concurrent neoadjuvant therapy followed by MIE.
Patient empowerment: a critical evaluation and prescription for a foundational definition
Authors: Varela Antonio J. , Gallamore Michael J. , Hansen Noah R. , Martin Dakota C. 
Published: January 2025

IntroductionThe evolution of healthcare continues to display an incongruence between delivery and outcomes. Current healthcare paradigms for patient empowerment warrants analysis. A lacking operational application for and agree upon assessment of patient empowerment contributes to healthcare’s incongruence. Interchangeable psychosocial concepts and specific patient contextual factors associated with health-related behavioral change have escaped an applicable definition of empowerment. The aim of this theoretical perspective review is to support a comprehensive and contextual understanding of patient empowerment that frames a definition for future consensus research.Methods and mechanismsA theoretical perspective review of patient empowerment including interchangeable concepts and patient contextual factors such as personal suffering and resilience; self-determined meaning and purpose; and autonomy, competence, and self-efficacy are critically analyzed. This analysis builds on adjacent concepts including therapeutic alliance, communication, motivation, and trust. The inclusion of specific patient contextual factors that relate to behavioral change elevate the need to reinforce coping and self-management skills as mechanism for patient empowerment. Practice gaps for those experiencing chronic disease, pain, and mental health disorders in rehabilitation setting are specific populations who benefit from healthcare providers unifying the variables associated with patient empowerment.Results and discussionThe review of associated concepts synthesized an actionable definition of patient empowerment that serves as a foundation for future research. Behavior related changes occur through the evolution in one’s identity, perceptions, and abilities. Interventions that inspire autonomy, competence, and relatedness with a renewed sense of purpose establish resilience and self-efficacy. The totality of this inspired self-determined plan of care establishes the mechanisms required for behavioral change and sustainable transformation. The cumulative experience becomes patient empowerment.
Sleep Pattern, Lifestyle Pattern, and Risks of Overall and 20 Types of Cancers: Findings From the UK Biobank Cohort
Authors: Zhao Yue-Ze , Zhang Wen-Li , Zhang Kai-Wen , He Yong-Qiao , Xue Wen-Qiong , Yang Da-Wei , Diao Hua , Xiao Ruo-Wen , Liao Ying , Wang Qiao-Ling , Jia Wei-Hua , Wang Tong-Min 
Published: January 2025

ObjectivesSleep health and other lifestyle behaviours are gaining increasing attention in public health, particularly for cancer prevention, but a comprehensive assessment is lacking.MethodsThe study included 380,042 UK Biobank participants. A healthy sleep score was constructed based on five sleep factors: chronotype, sleep duration, insomnia, snoring, and daytime dozing. A healthy lifestyle score was constructed based on four lifestyle factors: smoking, alcohol consumption, diet and physical activity. The effect of healthy sleep and lifestyle on cancer risk was examined by Cox proportional hazard models.ResultsBoth healthy sleep and lifestyle patterns were significantly associated with a reduced risk of overall cancer and specific cancer sites. Participants with healthy sleep and lifestyle patterns had a lower risk of overall cancer (HR = 0.72, 95% CI = 0.68–0.77), liver cancer (HR = 0.53, 95% CI = 0.31–0.90), bladder cancer (HR = 0.61, 95% CI = 0.47–0.79), lung cancer (HR = 0.22, 95% CI = 0.19–0.27), and colorectal cancer (HR = 0.80, 95% CI = 0.66–0.96) compared to those with unhealthy patterns.ConclusionOur findings highlight the importance of public health education and interventions to improve sleep and other lifestyle behaviours for cancer prevention.
Disability and Migration Routes: An Explorative Analysis Among Refugees Hosted in Italy
Authors: Tofani Marco , Marceca Maurizio , Valente Donatella , Galeoto Giovanni , Ben Zina Mohamed Ali , Salhi Imène Soumaya , Elmadmad Khadija , Tak Tak Hind , Gosling Justine , Mishra Satish , Gazzaniga Valentina , Cilione Marco , Iorio Silvia 
Published: January 2025

ObjectiveData on disability in refugees is lacking, hindering effectiveness of humanitarian response. We investigated disability condition in refugees, identifying possible mechanisms that affect their health.MethodsThe Washington Group Short Set – Enhanced was used to identify people at risk experiencing disability. Data on migration routes were collected and the relationship with functioning limitations was explored.Results483 refugees (58.18% males - 41.82% female) were interviewed. 23.8% were found to have a disability, with a higher risk for those who travelled along the central Mediterranean route OR (95% CI) 2.08 (1.33–3.24). Affect domain represented the main weight for disability (28.16%), followed by mobility limitation (8.28%). People who travelled across the central Mediterranean route were found to have a high risk of developing anxiety problems OR (95% CI) 2.19 (1.33–3.6), while people who crossed the Balkan route had a higher risk of mobility limitation OR (95% CI) 3.03 (1.23–7.44).ConclusionThis study provides the first available data on disability among refugees in Italy, revealing a high prevalence of disability and a significant association with migration routes. These findings underscore the urgent need for targeted health and rehabilitation interventions to address the specific vulnerabilities of this population.
A rare presentation of a retroperitoneal liver and kidney abscess: a case report
Authors: Fonseca Marayah Sampaio Ruas da , Brandão Vinícius Carvalho , Lerner Nicole , Maldonado Ligia Aranha Puig , Ramos Rodrigo Felippe 
Published: January 2025

Introduction: Liver abscess as well as kidney abscess is an uncommon condition, associated with multiple etiologies and its occurrence can lead to serious infectious conditions or even death. Those two entities occurring simultaneously is a rare condition. The quick identification and implementation of appropriate treatment is essential for mitigate sequelae. The article describes a case of a 45-year-old woman with a history of nephrolithiasis and recurrent pyelonephritis in the right kidney who was admitted to a tertiary hospital in Rio de Janeiro with abdominal pain in the right hypochondrium, nausea, vomiting and recent history of fever. Discussion: Laboratory changes were observed such as anemia, leukocytosis with left shift, elevated creatinine and CRP, in addition to positive urine culture for E. Coli ESBL. As the condition worsened, an exploratory laparotomy was performed, which revealed an abscess in hepatorenal cavity in segment VI. The culture of the peritoneal fluid and the collection revealed the presence of E. coli ESBL, such as the urine culture. The present case report aims to describe a severe presentation of bacterial liver abscess, in addition to providing a review of the literature on the different etiologies and clinical symptoms of this condition. Conclusion: It can be seen, therefore, that the liver abscess may have originating from a renal infectious focus that spread contiguously or via hematogenous to the liver. There is still the possibility that the long period of use of the double J catheter may have favored and/or perpetuated the disease.
Resultados de la aplicación de la estrategia didáctica aprendizaje basado en proyectos en la carrera de ISC en el TecNM Instituto Tecnológico de Minatitlán
Authors: Díaz Wendy Carranza , Nolasco Rosario Díaz , Castellanos María Elena Reyes , Martínez Fares Juda Ramírez , Santiago Victor Manuel Domínguez 
Published: January 2025

En este artículo se presenta una metodología didáctica diseñada para promover la elaboración de propuestas de proyectos por parte de los estudiantes enfocados al área de la ingeniería en sistemas computacionales, con el objetivo de promover y motivar en el alumnado la participación proactiva para el desarrollo de proyectos. La evaluación contó con la participación de un grupo de docentes incorporados al Tecnológico Nacional de México, del Instituto Tecnológico de Minatitlán quien con su experiencia e investigación diseñaron e implementaron la metodología propuesta. Dentro de lo más relevante de mencionar es la participación de estudiantes en áreas de desarrollo de sistemas computacionales, en eventos de fin de semestre. Al aplicar la metodología se reforzó las habilidades blandas del alumnado y se perfiló las competencias técnicas de su carrera y especialidad.