bluuebunny/crossref_metadata_2025_split huggingface dataset:
The possible protective effect of the nuclear factor kappa B inhibitor pyrrolidine dithiocarbamate on tramadol-induced testicular damage in rats
Authors: Mahmoud Abeer Ramzy Hussieny , Moursi Suzan M. M. , Esmaeel Safya E. , Mohamed Nesma Ismail Sharawy , Ali Nagah ElSayed Mohammed 
Published: June 2023

Abstract
Background
Tramadol provokes oxidative stress that gives rise to apoptosis with alterations in the cellular structure and adversely influences male fertility. A specific inhibitor of nuclear factor kappa B (NF-κB), pyrrolidine dithiocarbamate (PDTC), has observable antioxidant and anti-inflammatory characteristics and enhances the improvement of organs damage caused by various agents. The impact of PDTC on testicular damage caused by tramadol has not been previously examined.

Objective
This study was designed to investigate the potential impact of pyrrolidine dithiocarbamate on testicular damage provoked by chronic tramadol usage.

Materials and methods
Forty healthy adult male albino rats were included in this study. Rats were randomly and equally divided into 4 groups: group (I), control group; group (II), pyrrolidine dithiocarbamate (PDTC) group; group (III), tramadol (Tr) group; and group (IV), Tr + PDTC group. This study measured serum follicle-stimulating hormone (FSH), luteinizing hormone (LH), and free testosterone levels. Testicular malondialdehyde (MDA), interleukin-1β (IL-1β), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) levels, and superoxide dismutase (SOD), glutathione peroxidase (GPX), and caspase-8 and caspase-3 activities were also detected. Immuno-histochemical evaluation of inducible NOS (iNOS) expression in testicular tissue along with histopathological examination of testicular tissue has been studied.

Results
Tramadol caused a significant reduction in serum FSH, LH and testosterone levels, epididymal sperm count, and motility, as well as testicular GPX and SOD activities. On the other hand, a significant elevation of testicular MDA, IL-1β, IL-6, and TNF-α levels and caspase-8 and caspase-3 activities were found. However, PDTC administration with tramadol showed significantly increased sperm production and motility and alleviated tramadol-induced disturbance in other measured parameters in the Tr + PDTC group compared to the Tr group. Moreover, co-administration of PDTC with tramadol significantly alleviated the histopathological structure of testicular tissue and the increased iNOS expressions noticed in the tramadol-treated group.

Conclusion
Considering the protective effects of PDTC against the reproductive toxicity induced by tramadol, this compound can be used as a possible protective and treating target for tramadol-induced reproductive toxicity.
Taxonomy of Hyphodermella: a case study to show that simple phylogenies cannot always accurately place species in appropriate genera
Authors: Shen Shan , Liu Shi-Liang , Zhou Li-Wei 
Published: June 2023

AbstractThe genus is a special and crucial taxonomic rank compared with others above the species level, because a species has to be placed in a certain genus instead of any other higher ranks. With more and more new species being described, the placements of their generic position are sometimes incorrect due to the simple phylogenies resulting from inappropriate sampling. Here, we focus on the taxonomy of a small wood-inhabiting fungal genus Hyphodermella. With the most comprehensive sampling to date, the phylogenetic position of Hyphodermella within Phanerochaetaceae is rearranged by employing the same ITS and nLSU regions as in previous studies and also the ITS, nLSU, rpb1, rpb2 and tef1α regions. Three species are excluded from Hyphodermella: H. poroides is placed in a newly introduced monotypic genus Pseudohyphodermella, while H. aurantiaca and H. zixishanensis are transferred to Roseograndinia. Hyphodermella suiae is described as a new species from South China and Vietnam. Keys to eight species in Hyphodermella and five in Roseograndinia are provided. Beyond solving the taxonomic issue of Hyphodermella itself, the current study also aims to suggest that all fungal taxonomists especially beginners should keep in mind to sample as many comprehensive taxa as possible in phylogenetic analyses.
Acute presentation of locally advanced squamous cell carcinoma of frontal sinus—imaging findings of a rare entity: case report
Authors: Lahiri Ashim Kumar , Singh Kulvinder , Sherif Deia Mohamed Mohamed 
Published: June 2023

Abstract
Background
The squamous cell carcinoma is the most common subtype of malignant sinonasal tumours, predominantly involving the maxillary sinuses and nasal cavities in 70 to 80% of cases, and the frontal sinus is extremely rarely involved, in less than 1% of cases. Early clinical and radiological diagnosis is difficult due to overlap of findings with inflammatory sinonasal disease.

Case presentation
A 55-year-old Caucasian male patient had presented to the emergency department with three-month history of progressive right frontal swelling, acute frontal pain, recent exacerbation of right eye vision impairment and new lid swelling. There was no recent history of trauma and no neurological deficit on examination. Contrast-enhanced CT head was performed which demonstrated large bony destruction of frontal sinus with partly enhancing necrotic-looking tumour within the sinus. There was further intraorbital and intracranial extension of disease. Subsequent MRI confirmed these findings with better demonstration of intracranial and intraorbital component of the disease. The PET imaging did not reveal any avid disease elsewhere. Histopathology confirmed squamous cell carcinoma.

Conclusions
Frontal sinus squamous cell carcinoma is a rare and the least common site within the paranasal sinuses. Early clinical and imaging diagnosis could be challenging; however, the index of suspicion should be high with indeterminate imaging findings. CT and MRI are the complimentary imaging techniques.
Comprehensive measurement of the prevalence of dementia in low- and middle-income countries: STRiDE methodology and its application in Indonesia and South Africa
Authors: Farina Nicolas , Jacobs Roxanne , Turana Yuda , Fitri Fasihah Irfani , Schneider Marguerite , Theresia Imelda , Docrat Sumaiyah , Sani Tara Puspitarini , Augustina Lydia , Albanese Emiliano , Comas-Herrera Adelina , Du Toit Petra , Ferri Cleusa P. , Govia Ishtar , Ibnidris Aliaa , Knapp Martin , Banerjee Sube 
Published: June 2023

BackgroundA core element of the Strengthening Responses to Dementia in Developing Countries (STRiDE) programme was to generate novel data on the prevalence, cost and impact of dementia in low- and middle-income countries, to build better health policy. Indonesia and South Africa are two middle-income countries in need of such data.AimsTo present the STRiDE methodology and generate estimates of dementia prevalence in Indonesia and South Africa.MethodWe conducted community-based, single-phase, cross-sectional studies in Indonesia and South Africa, randomly sampling participants aged 65 years or older in each country. Dementia prevalence rates for each country were generated by using the 10/66 short schedule and applying its diagnostic algorithm. Weighted estimates were calculated with national sociodemographic data.ResultsData were collected between September and December 2021 in 2110 people in Indonesia and 408 people in South Africa. The adjusted weighted dementia prevalence was 27.9% (95% CI 25.2–28.9) in Indonesia and 12.5% (95% CI 9.5–16.0) in South Africa. Our results indicate that there could be >4.2 million people in Indonesia and >450 000 people in South Africa who have dementia. Only five participants (0.2%) in Indonesia and two (0.5%) in South Africa had been previously diagnosed with dementia.ConclusionsDespite prevalence estimates being high, formal diagnosis rates of dementia were very low across both countries (<1%). Further STRiDE investigations will provide indications of the impact and costs of dementia in these countries, but our results provide evidence that dementia needs to be prioritised within national health and social care policy agendas.
Care for older forensic mental health patients: A consensus guidance document
Authors: Tomlin Jack , Walker Kate , Yates Jen , Dening Tom , Goethals Kris , Völlm Birgit , Griffiths Chris 
Published: June 2023

Abstract

Background
It is important to investigate the needs, experiences, and outcomes of older forensic mental health inpatients. In this consensus document, we offer practitioners working with older forensic inpatients recommendations to meet the unique older-age-related needs of this group.

Method
We report on the findings of a scoping review of service provision and age-responsive interventions for this population. We complement this with a review of qualitative studies investigating staff and patient views on age-responsive inpatient care.

Results
The guidance synthesizes this evidence into sections on: epidemiological studies of demographic, clinical, and legal profiles; qualitative studies; investigations of patient need; evidence for interventions tailored to this patient group; future directions for research; and finally, recommendations for practice. Forensic patients over the age of 50 years have a different set of psychological and physical health needs from their peers. There is a dearth of dedicated interventions and support to assist patients through secure services and into the community.

Conclusions
We suggest service providers involve older patients in treatment and service organization decisions, adapt interventions to be responsive to this group, train staff to recognize physical vulnerabilities and cognitive decline, and embrace methods of communication developed in other areas of care, such as dementia Care.
John Guillory, Meet Kwasi Wiredu: A 1990s Guide to the Future English Department
Authors: Jackson Jeanne-Marie 
Published: June 2023

Abstract
This article pairs the arguments of Cultural Capital with those of Ghanaian decolonial philosopher Kwasi Wiredu. Writing around the same time as Guillory, Wiredu proposes a distinctive mode of decolonization, one focused on concepts rather than syllabi or curricula. In Wiredu's argument, decolonization ought to be a genealogical project, disentangling African thought from colonial impositions. The goal is not simple opposition but the chance to enable located concepts’ and traditions’ mutual interrogation, so that a “decolonized” thinker is one who can make an informed choice as to what analytic lenses or worldviews can or should be defended. Even as literary studies continues to open up possible texts and traditions for study, the bottom has fallen out of a hiring market organized around periodizing categories and national literatures. Turning back to Wiredu and Guillory together might not only help us think more clearly about the politics of literary study but also construct a version of the field based on concepts rather than national-historical fields.
Social Capital: Epic Fantasy and the Magical School
Authors: McGurl Mark 
Published: June 2023

Abstract
The term “cultural capital” has entered the general lexicon of cultural criticism as a description of social prestige won through the acquisition of knowledge rather than monetary wealth. And, yet, for all its utility in delineating the form of value acquired by students in the study of literature in school, cultural capital has proven limited in its ability to explain the dynamics of the contemporary literary field at large. Addressing this limitation, this essay reintroduces a lesser-known term from the work of Pierre Bourdieu, “social capital,” exploring how it becomes strikingly visible in one of the dominant popular genres of our time, epic fantasy.
Caenorhabditis elegansfor research on cancer hallmarks
Authors: Cerón Julián 
Published: June 2023

ABSTRACTAfter decades of research, our knowledge of the complexity of cancer mechanisms, elegantly summarized as ‘hallmarks of cancer’, is expanding, as are the therapeutic opportunities that this knowledge brings. However, cancer still needs intense research to diminish its tremendous impact. In this context, the use of simple model organisms such as Caenorhabditis elegans, in which the genetics of the apoptotic pathway was discovered, can facilitate the investigation of several cancer hallmarks. Amenable for genetic and drug screens, convenient for fast and efficient genome editing, and aligned with the 3Rs (‘Replacement, Reduction and Refinement’) principles for ethical animal research, C. elegans plays a significant role in unravelling the intricate network of cancer mechanisms and presents a promising option in clinical diagnosis and drug discovery.
The Hellenic landscape and the renewable energy sources. a social survey (2022) and some considerations
Authors: Kosmopoulos Panos 
Published: June 2023

The aim of this paper is to underline the urgent need for the application of R.E.S. in Greece, the related problems regarding the natural environment, the archaeological sites, the traditional architecture, and the existing contemporary urban environment. Some references to the theoretical approaches of the subject of environmental Aesthetics are also mentioned. The method to achieve conclusions has been a social survey of the opinions of Greek people, regarding their surrounding environment and the application of R.E.S.. Concluding the economic factor proves to be very important, primarily at the individual level and then at the social or national level, and the aesthetic factor seems to follow the economic one, but is also very important.
CZAS WOLNY W HIERARCHII WAŻNOŚCI DZIAŁAŃ DZIECI I MŁODZIEŻY W ŚWIECIE ICT – OPINIE UCZNIÓW I NAUCZYCIELI
Authors: Baron-Polańczyk Eunika 
Published: June 2023

W artykule przedstawiono fragment badań diagnostyczno-korelacyjnych o charakterze ilościowo-jakościowym, ustalających kompetencje informacyjne uczniów w zakresie wykorzystywania metod i narzędzi ICT. Podjęto w nim próbę odpowiedzi na pytanie o częstość korzystania przez dzieci i młodzież z ICT (hierarchię ważności działań) w obszarze pożytkowania czasu wolnego.Zastosowano metodę sondażu diagnostycznego (ankietę i wywiad) oraz metody statystyczne. Zbadano 2510 uczniów i 1110 nauczycieli. Ustalono, że: 1) według zagregowanej hierarchii ważności działań spędzaniu czasu wolnego w cyberprzestrzeni uczniowie nadali najmniejszą wagę (miejsce piąte), a nauczyciele małą wagę (miejsce czwarte); 2) istnieje związek (korelacja: nikła, ujemna, negatywna – r –0,06) między opinią uczniów a spostrzeżeniami nauczycieli co do częstości korzystania przez dzieci i młodzież z instrumentów ICT w celu spędzaniu czasu wolnego; 3) obliczenia wykazały istotne różnice statystyczne między częstością korzystania przez dzieci i młodzież z ICT jako formy spędzania czasu wolnego a: płcią, etapem kształcenia, miejscem (środowiskiem)nauki uczniów; 4) zauważalny jest niewielki rozdźwięk między opinią uczniów a nauczycieli, mało istotne „odseparowanie” świata dzieci i młodzieży („My”) od świata nauczycieli („Oni”).
use of social media and perception of body image and sense of coherence
Authors: Kłonowska Martyna , Radlińska Iwona 
Published: June 2023

Introduction and objective: One of the important factors that affect body perception is the beauty and body standards promoted by media and culture. Social media use can affect users' self-perception and sense of coherence. The study aimed to assess whether and how social media impact for body perception and sense of coherence.
Materials and methods: The study was conducted using an online questionnaire with a sample of 190 individuals, differentiated by gender. The Sense of Coherence Scale (SOC-29), Body Esteem Scale for Adolescents and Adults (BESAA), and a questionnaire developed for the study were utilized.
Results: In the study group, as the daily time spent on social media increased, the sense of manageability (rho = -0.171, p = 0.018) and meaningfulness (rho = -0.166, p = 0.022), as well as the overall coherence score (rho = -0.155, p = 0.033), decreased. Longer usage of social media platforms was associated with lower scores on the appearance scale (rho= -0.260; p<0.001) and weight scale (rho= -0.240; p=0.001), while remaining independent of the scores on the attribution scale (p>0.05).
Conclusions: The study shows that excessive use of social media can lead to a deterioration in body image and the amount of time spent on social media can contribute to the level of coherence. Conclusions highlight the need for implementing measures for the safe use of social media platforms and introducing psychoeducation on self-worth, body acceptance, and a sense of coherence, especially among young individuals.
The amplification of the bullwhip effect in the electronics industry under the influence of panic buying
Authors: Urbańczyk Tomasz 
Published: June 2023

Cel: Celem niniejszego artykułu było zbadanie przyczyn i skutków niedoborów w dostawach półprzewodników dla przemysłu motoryzacyjnego i elektronicznego w 2021 roku, opisanie zachowań menedżerów przedsiębiorstw, które się do tego przyczyniły, a także przedstawienie propozycji wzmocnienia odporności sieci dostaw na impulsy popytowe poprzez ich digitalizację oraz transparentność przepływów informacyjnych i rzeczowych.
Metodyka: Badanie oparto na źródłach wtórnych i pierwotnych. Przeprowadzono analizę danych wtórnych w postaci raportów polskich spółek giełdowych produkujących urządzenia elektroniczne za lata 2019 i 2021 pod kątem rotacji zapasów. Rok 2019 traktowany jest jako bazowy, tj. jeszcze przed pandemią Covid-19. Z kolei rok 2021 prezentuje okres, w którym producenci urządzeń elektronicznych doświadczali już istotnych opóźnień w dostawach półprzewodników. W odniesieniu do źródeł pierwotnych zostały przeprowadzone wywiady z jednym producentem półprzewodników i trzema producentami urządzeń elektronicznych.
Wyniki: Wzrost popytu na komponenty elektroniczne, wydłużenie czasów dostaw i ograniczenie ich dostępności spowodowało, iż producenci urządzeń elektronicznych w obawie przed postojami produkcyjnymi zwiększyli swoje zakupy i zapasy, tym bardziej nakręcając spiralę popytu i niedobory komponentów. Decyzje o powiększaniu zapasów w pewnym stopniu opierały się na praktyce dokonywania zakupów w panice i świadczyły o braku transparentności w łańcuchach dostaw.
Implikacje: Autor proponuje wdrożenie digitalizacji i transparentności sieci dostaw w miejsce dokonywania zakupów w panice, co w znacznym stopniu zredukowałoby przestoje produkcyjne producentów samochodów i urządzeń elektronicznych, jak również negatywne konsekwencje finansowe związane z postojami produkcyjnymi i złomowaniem przestarzałych zapasów.
Słowa kluczowe: efekt byczego bicza, zakupy dokonywane w panice, niedobory półprzewodników, zakłócenia w łańcuchu dostaw, Covid-19
Typ artykułu: Artykuł badawczy
A Longitudinal Study of the Impact of the Peer Support Programme on a Japanese Male-Dominated High School Through 6 Years Practices
Authors: Kondo Mitsuyo , Kato Hideo 
Published: June 2023

<p style="text-align:justify">This study explored the impact of the peer support programme on pupils at Japanese technical high school for over 6 years. A total of 268 pupils (an intervention group 112; a control group 114) were invited for the study and the pupils of the intervention group were given peer support training and they joined its supporting activities. All the pupils were assessed three times by adopting IRS, RSES10 and GHQ28. The results showed that the programme seemed to give positive influences on the peer supporters in terms of IRS, RSES10 and GHQ28. Also, both group members were classified into low-scoring groups and high-scoring groups, depending on their scores at the first assessment. Then, the results of analysis showed that the pupils from both low & high -scoring groups significantly improved their scores in IRS. In RSES10 and GHQ28, the pupils from the low-scoring groups improved their scores, but those from the high-scoring groups did not improve much. As a conclusion, even in a technical high school where the majority of pupils was male pupils (over 90%), the peer support programme seemed to give positive influences on the peer supporters in terms of IRS, RSES10 and GHQ28. </p>
Efficacy of nitrous oxide in adults undergoing puncture biopsy: A systematic review and meta-analysis of randomized controlled trials
Authors: Wang Ziyang , Wang Fei , Xing Yihui , Jiang Xiaochen , Ding Zhiguo , Li Yuxiang , Tang Lu 
Published: June 2023

BackgroundNitrous oxide (N2O) with rapid analgesic effect is often used to relieve pain induced by diagnostic procedures. This review was conducted to evaluate the efficacy and safety of N2O in patients undergoing puncture biopsy.MethodsWe systematically searched PubMed, Embase, the Cochrane Library, Web of Science, Scopus and the ClinicalTrials.gov up to March, 2022. Randomized controlled trials (RCTs) were included if they investigated the effect of N2O in adults undergoing puncture biopsy. The primary outcome was pain score. Secondary outcomes included anxiety score, patient satisfaction and side effects.ResultsTwelve RCTs with 1070 patients were included in the qualitative review, of which eleven RCTs were included in the meta-analysis. Pooled analysis suggested that compared with the controls (placebo, lidocaine and midazolam), N2O had better analgesic effect (MD -1.12, 95% CI -2.12 to -0.13, P = 0.03; I2= 94%). In addition, N2O significantly alleviated patient anxiety (MD = -1.79, 95% CI -2.41 to -1.18, P<0.00001; I2= 0%) and improved patient satisfaction (MD 1.81, 95% CI 0.11 to 3.50, P = 0.04; I2= 92%). There was no significant difference regrading the risk of nausea (RR 2.56; 95% CI 0.70 to 9.31, P = 0.15; I2= 0%), headache (RR 0.62, 95% CI 0.17 to 2.33, P = 0.48; I2= 46%), dizziness (RR 1.80, 95% CI 0.63 to 5.13, P = 0.27; I2= 0%) or euphoria (RR 2.67, 95% CI 0.81 to 8.79, P = 0.11; I2= 8%) between the N2O group and the control group.ConclusionThe present review suggested that N2O might be effective for pain management in patients undergoing puncture biopsy.