bluuebunny/crossref_metadata_2025_split huggingface dataset:
Memory Malware Analysis: Detecting Malicious Signatures In Memory By VolatilityPlugin’s
Authors: Reddy Karthik Kumar , Bhattacharya Tathagata , Reddy Shreevan 
Published: January 2023

AbstractMemory forensics is used to implement and investigate malware that is executed or stored in RAM. Whether it is static malware analysis or dynamic malware analysis,each time the malware investigator retrieves the result, it is displayed in plaintext, and the investigator begins examining each result in the plaintext and triaging the malicious request. It's a labor-intensive process, and occasionally an investigator will upload malicious files to his or her computer to be analyzed for malware. These malicious files could contain worms or have the potential to infect the investigator's computer; if that happens, the attacker will keep an eye on all future investigations and the evidence they produce. With the help of this research and algorithm, whenever a malicious DLL or request is made, the algorithm will be able to identify it and flag it. This will save the investigator a lot of time because the investigator can upload files to his or her computer without worrying about whether they will be flagged as malicious behavior. We experimented wih multiple malicious files and our algorithm shows 98% efficacy.
Are anti-SARS-CoV-2 S/N IgG/IgM antibodies always predictive of previous SARS-CoV-2 infection?
Authors: Lippi Giuseppe , Henry Brandon M. , Pighi Laura , De Nitto Simone , Salvagno Gian Luca 
Published: January 2023

Abstract
BACKGROUND. We planned this study to verify whether immunoassays for quantifying anti-SARS-CoV-2 IgG/IgM antibodies against both spike (S) and nucleocapsid (N) proteins may be used for identifying previous SARS-CoV-2 infections.
METHODS. The study population consisted of a cohort of fully vaccinated healthcare workers. All study subjects underwent regular medical visits and molecular testing for diagnosing SARS-CoV-2 infections every 2-4 weeks since 2020. Venous blood was drawn for measuring anti-SARS-CoV-2 antibodies with MAGLUMI 2019-nCoV lgG/IgM CLIA Assays directed against both SARS-CoV-2 S and N proteins.
RESULTS. Overall, 31 (58.5%) subjects had tested positive for SARS-CoV-2 by RT-PCR throughout the study (24 once, 7 twice). No positive correlation was found between anti-SARS-CoV-2 S/N IgM antibodies and molecular test positivity. In univariate regression analysis, both a molecular test positivity (r=0.33; p=0.015) and the number of positive molecular tests (r=0.43; p=0.001), but not vaccine doses (r= -0.12; p=0.392), were significantly correlated with anti-SARS-CoV-2 S/N IgG antibodies. These two associations remained significant in multiple linear regression analysis (p=0.029 and p<0.001, respectively) after adjusting for sex, age, body mass index, and vaccine doses. In ROC curve analysis, anti-SARS-CoV-2 S/N IgG antibodies significantly predicted molecular test positivity (AUC, 0.69; 95%CI; 0.55-0.84), with the best cut-off of 0.05 AU/mL displaying 67.9% accuracy, 0.97 sensitivity, and 0.27 specificity.
CONCLUSION. Although anti-SARS-CoV-2 S/N IgG antibodies provides helpful information for identifying previous SARS-CoV-2 infections, a lower cutoff than that of sample reactivity should be used. Anti-SARS-CoV-2 S/N IgM antibodies seem useless for this purpose.
Ultra-high dose rate dosimetry with miniaturized scintillation detectors coupled to optical fibers
Authors: Casolaro Pierluigi , Dellepiane Gaia , Gottstein Alexander , Mateu Isidre , Scampoli Paola , Braccini Saverio 
Published: January 2023

Abstract
FLASH radiotherapy is a novel radiation delivery modality, generally considered a potential breakthrough in cancer care. With ultra-high dose rates (>40 Gy/s) delivered in fractions of a second, FLASH is characterized by unique irradiation conditions which bring along new challenges in dosimetry and beam monitoring. This article reports on the validation of innovative detection systems based on sub-millimeter-sized fast scintillation detectors coupled to optical fibers. We characterized different scintillators, namely Gadolinium Aluminium Gallium Garnet (GAGG), yttrium doped barium fluoride (Y-BaF2), and polystyrene, by studying their response to ultra-high dose rate 18 MeV proton beams. Beam tests were carried out at the Bern medical cyclotron, providing beams for multidisciplinary research activities and commercial radioisotope production, that we characterized for ultra-high dose rates irradiations. The possibility of changing the scintillator to be coupled to the optical fiber gives great flexibility to the system, by allowing to measure proton dose rates up 10.4 kGy/s and mm-small fields with high time resolution. The measurements reported in this paper were performed at a sampling rate of 20 kHz, although data acquisition up to 10 MHz is possible. The developed detection system can be successfully used to measure ultra-high dose rates and it can be further optimized to address specific and essential issues of FLASH radiation therapy, including quality assurance, real-time beam monitoring and in-vivo dosimetry.
A qualitative study of traditional healthcare practices: evidence from Ilorin less city
Authors: Olaitan Ahmed Ahmed , Ibrahim Muhammad Asmawi , Olubukola Nosiru Mojisola , Morenike Tokede Abiodun 
Published: January 2023

The object of research: This study aimed to explore different forms of healthcare practice in Egbejila an Ilorin less city, Nigeria.
The investigated problem: Throughout the world, traditional healthcare practice leads the edge with regards to healthcare delivery for humanity. It follows that rural inhabitants marshal various forms of healthcare practice. This study investigated peculiar healthcare practices performed by traditional healthcare practitioners in Egbejila a rural Nigeria.
The main scientific results: The research study unveiled different and various dimensions and approaches of healthcare practice that are visualized and sustained as an indispensable component of continuity and survival of human entity.
The area of practical use of the research results: The results of this research study gave insight to various traditional healthcare services being sought after by rural inhabitants of variant cultural, religious, socio-political and economic backgrounds aside the orthodox medicine.
Scope of the innovative technological product: The study adopted purposive sampling procedure for the selection of key informants. A total of twenty-five (25) key informants were purposively selected. Data obtained through the recorded interviews were transcribed into Microsoft Word and was analyzed by using N-Vivo software
Distance learning technology in training competent master of dentistry under extreme conditions by evaluation of foreign students
Authors: Kulbashna Yaroslava , Skrypnyk Iryna , Kryzhanivska Oksana 
Published: January 2023

The object of research: Masters of Dentistry professional training in Bogomolets National Medical University (Kyiv, Ukraine) with the distance learning technology
Investigated problem: Educational process in extreme condition as pandemics and wars, possible ways to solve the problem how students and teachers cope with both challenges in Ukraine on the way of preparing competent doctor from the point of view of foreign students.
The main scientific results: Preliminary data of medical university students from foreign countries - future masters in dentistry of the Bogomolets Medical University (Kyiv, Ukraine) survey, conducted in term April-November 2022 about their perceptions of online learning and teaching in extreme conditions as they experienced during lockdown in terms of COVID -19 outbreak and continuing russian`s aggressive war in Ukraine. Our findings from survey concern questions of student`s general view on online educational technology as well peculiarities of approaches in teaching we can use for acceptable in such extreme conditions educational outcome. We start discussion about some useful methodological approaches for distance education technology in extreme conditions.
The area of practical use of the research results: Sharing with educational community our experience and features about distant learning in extreme conditions of dental students.
Experimental investigation of water to air heat exchanger performance as passive cooling strategy on ventilation system in tropical region
Authors: Lapisa Remon , Kurniawan Andre , Jasman Jasman , Yuvenda Dori , Putra Randi Purnama , Waskito Waskito , Karudin Arwizet , Krismadinata Krismadinata 
Published: January 2023

This experimental study aims to investigate and analyze the performance of a Water-Air Heat Exchanger that functions as passive cooling in a building ventilation system in the tropics. Before being blown into the room, the high-temperature outdoor air will be passively cooled by the lower-temperature water. Air driven by an Inline Duct Fan with a constant mass flow rate of 4.68 cubic meters per minute flows through a PVC hose as a heat exchanger inserted into a full water reservoir with a diameter of 100 cm and a height of 110 cm. A heat exchanger hose with a diameter of 6.35 cm and a length of 4130 cm is installed in a spiral-circular manner with a total of 16 coils with a diameter of 80 cm to increase the heat transfer effectiveness between water and air. The passive cooling effectiveness is analyzed by decreasing the air temperature between the inlet and outlet of the ventilator after passing through the heat exchanger. The temperature, humidity, and daylight measurement data were carried out for 36 consecutive hours using a multichannel data logger at several locations; ventilator inlet, ventilator outlet, water in the tub, and outside air. The measurement results show that the designed water-to-air heat exchanger provides a significant passive cooling effect and can reduce air temperature to 6.88 °C. By utilizing the passive cooling effect, the cooling energy gain obtained during the measurement period in the ventilation system of this building is 8.3 kWh. The methodology and results of this research are expected to make a positive contribution to the development of the concept of energy-efficient buildings by using passive cooling techniques
Determination of the green function of a pulsed acoustic source in a uniform homogeneous flow with an arbitrary Mach number
Authors: Bryukhovetski Anatoliy , Vichkan' Aleksey 
Published: January 2023

The wave field created by a pulsed point source of sound in a uniform homogeneous flow with an arbitrary value of the Mach number is theoretically studied. The aim of research is to obtain an analytical dependence of the sound field on physical parameters.
The space-waveguide Fourier expansion of the sound field is used to solve the Cauchy problem for the wave equation in a reference frame moving together with the medium. It is only necessary to transform the spatiotemporal dependence of the source, given in a fixed frame of reference, to a dependence in a moving frame of reference.
The transition to the description of the solution in the frame of reference, relative to which the medium moves at a constant velocity, is made taking into account the main properties of the generalized Dirac δ-function.
Analytical dependences of the sound field on physical parameters are obtained for both subsonic and supersonic flows. A comparison is made with the results of calculations for the case of a pulsed point source moving in a medium at rest. The solution obtained in this work for the case of an impulsive source moving in a medium at rest made it possible to trace its connection with the Green's function for a stationary source in a moving medium. The analytical dependence of the obtained solution for the Green's function makes it possible to write down the explicit form of the "characteristic solution surface", that is, the "wave front". It is shown that the difference between the solutions for subsonic and supersonic motion is characterized by the position of the source relative to the moving wavefront.
The calculation results can be used to describe the sound field created by an arbitrary spatiotemporal distribution of sound sources
The development of carbon monoxide oxidation reactor for multi-chamber furnaces for baking electrode blanks
Authors: Ivanenko Olena , Trypolskyi Andrii , Khokhotva Оleksandr , Mikulionok Igor , Karvatskii Anton , Radovenchyk Vyacheslav , Plashykhin Sergii , Overchenko Tanya , Dovholap Serhii , Strizhak Peter 
Published: January 2023

The article highlights the development of cheap affordable highly efficient catalytic oxidation system of harmful components of industrial flue gases of carbon graphite enterprises, its design features according to the parameters of furnace equipment, which will significantly improve the environmental safety of metallurgical and machine-building enterprises. The presented calculation and design solutions, in addition to carbon production, can be used in environmental protection technologies at other environmentally hazardous facilities to neutralize toxic emissions.
The paper presents the calculation of the catalytic CO oxidation reactor made for the real flow rate of flue gases with temperature range 270−390 ºC, which come out of the combustion chamber of the Riedhammer "first fire" kiln, heated by the flue gases. For such medium exothermic processes, mass and heat transfer between gas flow and the outer surface of the catalyst grains is sufficient intense. In this case for description of the catalytic process in the reactor is sufficient to use quasi-homogeneous single-phase model.
The model of plug-flow reactor with a fixed bed of catalyst was used to calculate the flow parameters of the gas mixture through a reactor loaded with a composite zeolite-based manganese-oxide catalyst in the process of catalytic CO oxidation. The calculation results obtained using the software CHEMCAD 7.1.5 were almost identical to the previously made calculation. The peculiarity of the suggested solution was the use of the designed catalytic reactor for treatment of large volume of flue gases with low concentrations of CO at the companies of electrode carbon graphite production
Apparent prevalence of brucellosis, Q-fever and toxoplasmosis in aborted goat’s at North Shoa, Ethiopia
Authors: Alamerew Enyiew Alemnew , Yitagesu Erdachew , Areaya Alemnew , Aydefruhim Derib 
Published: January 2023

Abortion imposes great economical loss in productivity and by product of small ruminants. The present study was conducted to determine the rate of abortion and apparent prevalence of Brucellosis, Toxoplasmosis and Q-fever in aborted goats from June 2015 to August 2019 in North Shoa, Ethiopia. During consecutive years of clinical case study 503 does were entered to mating, of which100 (19.5 %) animals aborted. There were significant differences (p=0.013) in abortion among parities. A total of 35 serum samples were collected from aborted does within six months periods. All samples were screened initially with Rose Bengal plate test (RBPT) for Brucellosis. All RBPT positive were further tested by i-ELISA. Also, serums were tasted to screen specific antibody against Q-fever and Toxoplasmosis using i-ELISA. Of total tested 64.7 % and 8.6 % of them were positive for Q-fever and Toxoplasmosis, respectively, but neither of them was positive for Brucellosis. The present clinical study revealed that abortion was the cause of kids’ loss and serological investigation of antibody against Q-fever and Toxoplasmosis showed that the agents were the major causes of abortion. Even though there was no positive reactor does to brucellosis, the result must be interpreted with care since absence of evidence is not evidence of absence. Beside of this, some samples collected from active cases were sero-negative for neither of tested antibodies; it indicated there was other cause/s of abortion in the study site. These interesting findings deserve further detail study by using more sensitive diagnostic test in order to examine the full extent of the problem in small ruminant populations. Also, an awareness-raising campaign should be launched to educate farm workers and professionals about proper preventive and control measures for such zoonotic diseases
Tongue rolling and hand clasping among various ABO blood groups in a University community in Eastern Nigeria
Authors: Nwosu Nkechi Clara , Onwuka Osah Martins , Bob-Manuel Ibinabo Fubara 
Published: January 2023

Morphogenetic traits are physical observable traits that can be inherited either in a single gene or multifactorial pattern. ABO blood group is a codominant inherited trait that has been associated with different anatomical and physiological variations. However, there are limited studies that have linked ABO blood groups with some morphogenetic traits.
This study was conducted to ascertain the distribution of morphogenetic traits like hand clasping and tongue rolling among ABO blood groups in a University community in Eastern Nigeria.
A total of 115 volunteers participated in the study. The blood groups of the participants were determined and the expression of the morphogenetic traits was gotten by physical observation. Greater proportion of the participants were males (55.65 %), students (61.74 %) and within ages 15−25 (58.26 %). There was a higher prevalence of blood group O (57.39 %), tongue non-rollers (53.04 %) and right hand clasping (74.78 %) among the participants. The participants with blood groups A and O recorded a higher distribution of tongue non-rollers while those with blood groups B and AB recorded an equal number of both tongue roller and non-rollers. The participants with blood groups A, B and O recorded a higher distribution of right hand clasping while those with blood group AB recorded a significant higher distribution of left hand clasping (P<0.05).
In conclusion, morphogenetic pattern of tongue rolling could not be associated with ABO blood group, whereas that of left hand clasping was associated with blood group AB suggesting that individuals with blood group AB is likely to exhibit left hand clasping; forming basis for determination of hand clasping using ABO blood group in future advancement of genetics and forensic science
Evaluation of the association of CES1 (rs2244613) polymorphisms with the safety of remdesivir in hospitalized patients with COVID-19
Authors: Temirbulatov I. I. , Kryukov A. V. , Mirzaev K. B. , Denisenko N. P. , Abdullaev Sh. P. , Kachanova A. A. , Sozaeva Zh. A. , Zhiryakova A. S. , Shevchuk Yu. V. , Vechorko V. I. , Averkov O. V. , Sychev D. A. 
Published: January 2023

Introduction. An outbreak of novel COVID-19 infection has become a real challenge for the entire human society, and first of all for the healthcare services. The development of new drugs is a complex and lengthy process. At the beginning of the pandemic, it forced an intensive study of well-known drugs for the therapy. Remdesivir was first investigated as a potential treatment for Ebola virus. After beginning of the COVID-19 pandemic, in vitro evaluations demonstrated its activity against SARS-CoV-2. Subsequent clinical studies showed the efficacy of remdesivir in shortening the time to recovery.Aim. To evaluate the effect of the carriage of polymorphic alleles of the CES1 gene (A > C, rs2244613) on the safety profile of remdesivir therapy.Materials and methods. A total of 154 patients hospitalized with coronavirus infection were included in the study. All patients received remdesivir as etiotropic therapy in the standard regimen: 200 mg on the first day followed by 100 mg daily for 5-10 days. In the course of observations, clinical and laboratory signs of adverse events were reported. Venous blood samples were collected from each patient for pharmacogenetic studies. Genotyping was performed using the real-time polymerase chain reaction technique. Statistical analysis: вata were analysed by using IBM SPSS Statistics, Version 23.0.Results. There were no significant associations of carriage of various CES1 variants with the frequency of adverse reactions (bradycardia, nausea, vomiting) and laboratory markers of adverse events (ALT, AST, creatinine levels).Conclusion. In our study, no association was found between the carriage of CES1 gene polymorphisms and the safety parameters of remdesivir in hospitalized patients with COVID-19. Further research into the possibilities of personalizing COVID-19 therapy through pharmacogenetic testing is needed.
Cognitive disorders in patients with cerebrovascular diseases in therapeutic practice: diagnostic and management algorithms
Authors: Shishkova V. N. 
Published: January 2023

This review summaries the main present-day knowledge on the pathogenesis of cognitive impairement in patients with cardiovascular and cerebrovascular diseases, combining both the development of severe forms such as dementia, and early non-dementia forms of cognitive impairment. Risk factors, including iatrogenic ones, and the mechanisms of development of various forms of cognitive impairment in patients with vascular pathologies are discussed in detail. The definition of human cognitive functions and the modern classification of cognitive impairment used in real clinical practice are given. The clinical aspects of cognitive impairment in the therapeutic practice with a focus on the review of a wide range of specific complaints, reflecting the likelihood of cognitive impairment and non-cognitive symptoms are considered in detail, taking into account the current national clinical guidelines of professional communities. Possible iatrogenic factors that worsen the state of cognitive functions, including an assessment of the anticholinergic drug load on the patient are discussed in detail, and a strategy for identifying and solving this issue as part of a therapeutic approach is provided. An algorithmic approach to the identification of non-dementia cognitive impairment in patients with cerebrovascular pathology is presented by therapeutic specialists working in the primary outpatient healthcare sector. The laboratory and instrumental examination options for patients to identify reversible forms of cognitive impairment are considered in detail. The prospective of choosing preventive non-drug and drug approaches, as well as the therapeutic strategy options for the use of drugs that improve the central nervous system functioning during management of patients with cerebrovascular diseases, depending on the type of cognitive impairment in the general practitioner practice are assessed.
Assessing drinking water quality and health risks of contaminants in the coastal areas of Cambodia
Authors: Sao Vibol , Chey Chan Oeurn , Sriv Tharith , The Noreaksatya , Phin Samnang , Hoeng Sophanith , Phan Kongkea 
Published: January 2023

Abstract
The present study aimed to assess the health risks of chemical contaminants of residents in the coastal areas of Cambodia through their drinking water pathways. Water was sampled from tube wells (n= 22), dug wells (n= 31), ponds (n= 11), canals (n= 12) and lakes (n= 4) across the Cambodian coastal areas, and measured for the contaminants of health concern (As, Cu, Cr, Cd, F−, NO2-, NO3-, Pb, Escherichia coli and total coliform) and aesthetic quality following the United States Environmental Protection Agency (USEPA) and standard methods. Analytical results reveal that 9.1% of tube wells and 9.7% of dug wells contained As &gt; 0.01 mg/L. Appropriately, 22.7% of tube wells and 32.3% of dug wells contained Fe &gt; 0.3 mg/L while 100% of tube wells and 80.6% of dug wells contained Mn &gt; 0.1 mg/L. Health risk assessment found that the hazard quotient (HQ) &gt; 1 for children and women. Additionally, the lifetime cancer risk (LCR) was found &gt;1 × 10−4 for As in Cambodian coastal areas. Therefore, a monitoring programme and appropriate treatment to remove contaminants like arsenic, cadmium and fluoride would be required to ensure a safe drinking water supply to Cambodian coastal residents.