bluuebunny/crossref_metadata_2025_split huggingface dataset:
Satellite-based estimates of groundwater storage depletion over Egypt
Authors: Shalby Ahmed , Emara Sobhy R. , Metwally Mohammed I. , Armanuos Asaad M. , El-Agha Doaa E. , Negm Abdelazim M. , Gado Tamer A. 
Published: April 2023

AbstractAn arid climate accompanied by a freshwater shortage plagued Egypt. It has resorted to groundwater reserves to meet the increasing water demands. Fossil aquifers were lately adopted as the sole water source to provide the irrigation water requirements of the ongoing reclamation activities in barren areas. Yet, the scarcity of measurements regarding the changes in the aquifers’ storage poses a great challenge to such sustainable resource management. In this context, the Gravity Recovery and Climate Experiment (GRACE) mission enables a novel consistent approach to deriving aquifers’ storage changes. In this study, the GRACE monthly solutions during the period 2003–2021 were utilized to estimate alterations in terrestrial water storage (TWS) throughout Egypt. Changes in groundwater storage (GWS) were inferred by subtracting soil water content, derived from the GLDAS-NOAH hydrological model, from the retrieved TWS. The secular trends in TWS and GWS were obtained using the linear least square method, while the non-parametric technique (Mann–Kendall’s tau) was applied to check the trend significance. The derived changes in GWS showed that all aquifers are undergoing a significant loss rate in their storage. The average depletion rate over the Sinai Peninsula was estimated at 0.64 ± 0.03 cm/year, while the depletion rate over the Nile delta aquifer was 0.32 ± 0.03 cm/year. During the investigated period (2003–2021), the extracted groundwater quantity from the Nubian aquifer in the Western Desert is estimated at nearly 7.25 km3. The storage loss from the Moghra aquifer has significantly increased from 32 Mm3/year (2003–2009) to 262 Mm3/year (2015–2021). This reflects the aquifer exposure for extensive water pumping to irrigate newly cultivated lands. The derived findings on the aquifers’ storage losses provide a vital source of information for the decision-makers to be employed for short- and long-term groundwater management.
The Rise of Vancouver and the Collapse of Forage Fish: A Story of Urbanization and the Destruction of an Aquatic Ecosystem on the Salish Sea (1885–1920 CE)
Authors: Morin Jesse , Evans Aaron Blake , Efford Meaghan 
Published: April 2023

AbstractSince its establishment as a Euro-Canadian settlement in the mid-nineteenth century, the marine ecology surrounding Vancouver in British Columbia, Canada, has been negatively impacted by urban development, habitat destruction, poor fisheries practices, and pollution. Focussing on forage fish – herring, smelt, and eulachon – we present the results of an extensive meta-analysis including an archaeological, ethnohistoric, and scientific/regulatory literature review of Indigenous and commercial fisheries’ harvesting records to track the early historic collapse of these fisheries from about 1885–1920 CE. We identify significant reductions in the major forage fish fisheries around Vancouver within decades of the initial Euro-Canadian settlement. These severe negative effects occurred long before scientific description of local ecosystems had begun, and the magnitude of these effects went generally unrecognized and/or are poorly understood. We argue that this is a case of the shifting baseline syndrome (SBS): each generation of researchers mistakenly assumes that modern ecological conditions they encounter approximate their natural pre-contact state.
Cueing in Theatre: Timing and Temporal Variance in Rehearsals of Scene Transitions
Authors: Norrthon Stefan 
Published: April 2023

AbstractThis video-ethnographic study explores how professional actors and a director at the end of a theatrical rehearsal process coordinate transitions between rehearsed scenes. This is done through the development and use ofcues, that is, ‘signals for action’. The aim is to understand how cues are developed and how timing in transitions is achieved by using the designed cues. Work on three different scene transitions is analysed using multimodal Conversation Analysis. The results show that cueing is a central tool for developing well-timed transitions, and how cues serve different purposes in the developing performance. There is no prior plan for how to achieve timely transitions. In all the analysed examples, it is an actor who must produce or act on the given cue who insists on its precise definition, followed by a negotiation on candidate cues, confirmation and specifying the cue. It is also actors who are primarily responsible for the timing of transitions, and the timing is solved through an interplay of clear-cut and embodied actions that allow for temporal variance. Cues are reflexively linked to actors’ observation and interpretation of other actors’ actions, which prevents a mechanical determination of timing in scene transition.
Visual Attention to Dynamic Emotional Faces in Adults on the Autism Spectrum
Authors: Macinska Sylwia , Lindsay Shane , Jellema Tjeerd 
Published: April 2023

AbstractUsing eye-tracking, we studied allocation of attention to faces where the emotional expression and eye-gaze dynamically changed in an ecologically-valid manner. We tested typically-developed (TD) adults low or high in autistic-like traits (Experiment 1), and adults with high-functioning autism (HFA; Experiment 2). All groups fixated more on the eyes than on any of the other facial area, regardless of emotion and gaze direction, though the HFA group fixated less on the eyes and more on the nose than TD controls. The sequence of dynamic facial changes affected the groups similarly, with reduced attention to the eyes and increased attention to the mouth. The results suggest that dynamic emotional face scanning patterns are stereotypical and differ only modestly between TD and HFA adults.
Measuring policy coherence on global access to clean energy between European countries
Authors: Coscieme Luca , Ochieng Caroline A. , Spillane Charles , Donohue Ian 
Published: April 2023

AbstractAmongst the Sustainable Development Goals (SDGs), ensuring energy access in developing countries while reducing global emissions of greenhouse gases is critical. To achieve such goals, international cooperation combined with investments in research, technology, infrastructures and capacity building are paramount. The Sustainable Development Goal (SDG) 7 on access to affordable and clean energy, includes both targets at the domestic and international stages of energy policy. However, trade-offs are emerging in the monitoring phase of SDG7 and its targets, signalling the need for stronger coherence at all stages. Here, we assess to what extent policy coherence exists, and is or is not maintained, considering internal and external energy policy in Europe. We find that a higher level of coherence exists in internal than external energy policy. This result questions the overall positive contribution and commitment of European countries when it comes to facilitating energy access in developing countries. The results also highlight the positive effect of common policy frameworks and the need to rely more extensively on new means for governing and improving international policy coherence. We identify key trade-offs and co-benefits to be addressed for achieving improved policy coherence and call for a common framework that unifies internal and external energy policy in Europe for accelerating progress towards global access to clean energy.
Transferable IncX3 plasmid harboring blaNDM-1, bleMBL, and aph(3’)-VI genes from Klebsiella pneumoniae conferring phenotypic carbapenem resistance in E. coli
Authors: Elshamy Ann A. , Saleh Sarra E. , Aboshanab Khaled M. , Aboulwafa Mohammad M. , Hassouna Nadia A. 
Published: April 2023

Abstract
Background
The dissemination of carbapenem resistance via carbapenemases, such as the metallo-β-lactamase NDM, among Enterobacterales poses a public health threat. The aim of this study was to characterize a plasmid carrying the blaNDM-1 gene, which was extracted from a clinical Klebsiella pneumoniae uropathogen from an Egyptian patient suffering from a urinary tract infection.

Methods and results
The recovered plasmid was transformed into competent E. coli DH5α which acquired phenotypic resistance to cefoxitin, ceftazidime, and ampicillin/sulbactam, and intermediate sensitivity to ceftriaxone and imipenem (a carbapenem). Whole plasmid sequencing was performed on the extracted plasmid using the DNBSEQ™ platform. The obtained forward and reverse reads were assembled into contigs using the PRINSEQ and PLACNETw web tools. The obtained contigs were uploaded to PlasmidFinder and ResFinder for in silico plasmid typing and detection of antimicrobial resistance genes, respectively. The final consensus sequence was obtained using the Staden Package software. The plasmid (pNDMKP37, NCBI accession OK623716.1) was typed as an IncX3 plasmid with a size of 46,160 bp and harbored the antibiotic resistance genes blaNDM-1, bleMBL, and aph(3’)-VI. The plasmid also carried mobile genetic elements involved in the dissemination of antimicrobial resistance including insertion sequences IS30, IS630, and IS26.

Conclusions
This is Egypt’s first report of a transmissible plasmid co-harboring blaNDM-1 and aph(3’)-VI genes. Moreover, the respective plasmid is of great medical concern as it has caused the horizontal transmission of multidrug-resistant phenotypes to the transformant. Therefore, new guidelines should be implemented for the rational use of broad-spectrum antibiotics, particularly carbapenems.
Assessment of Escherichia coli-derived Recombinant Human Bone Morphogenic Protein-2 on Fertilization and Early Embryonic Development in Rats
Authors: Kim Nam Hyun , Min Seul Ki , Lee Myeong Wook , Kang Seung-Hoon 
Published: April 2023

Abstract
Objective
Bone morphogenetic protein-2 (BMP-2) impacts fertility in women by affecting the menstrual cycle and embryonic development. We aimed to determine the reproductive toxicity of Escherichia coli (E. coli)-derived recombinant human BMP-2 (rhBMP-2) by measuring changes in the reproductive performance and organs in rhBMP-2-treated rats.

Methods
Overall, 88 male and female rats each were categorized into one control and three experimental groups. rhBMP-2 was intravenously administered to the experimental groups at 0.05, 0.15, and 0.50 mg/kg/day, respectively. The male rats were administered rhBMP-2 daily, starting from 28 days before mating until the day of necropsy (48 days), after which they were euthanized and necropsied. The female rats were administered rhBMP-2 daily, starting from 14 days before mating until 7 days after fertilization (22–36 days), after which they were necropsied 13 days after fertilization.

Results
No rhBMP-2-related death occurred throughout the study period. All rhBMP-2-treated groups showed swelling in the tail at the site of rhBMP-2 administration. In the high-dose rhBMP-2 group, the male rats showed a slight reduction in body weight and food consumption, whereas the female rats showed a reduction in the weights of the ovary and oviduct. Examining the fertilization status and necropsy showed no effect of rhBMP-2 on fertility and early embryonic development. The no-observed-adverse-effect level of rhBMP-2 was 0.50 mg/kg/day in all rats.

Conclusion
rhBMP-2 had no reproductive toxicity on the reproductive performance and organs in female and male rats. Therefore, these results provide new toxicology information on E. coli-derived rhBMP-2 as a therapeutic protein.
Community pharmacists’ acceptability of pharmacist-delivered depression screening for older adults: a qualitative study
Authors: Gide Duha N. , El-Den Sarira , Lee Yee Lam Elim , Gisev Natasa , Ou Kevin , O’Reilly Claire L. 
Published: April 2023

Abstract
Background
Late-life depression often goes underdiagnosed and undertreated, affecting the quality of life of older adults. Pharmacists are well-placed to identify older adults who may be at risk of depression by using appropriate screening tools.

Aim
To explore community pharmacists’ acceptability of performing late-life depression screening in Australian community pharmacies.

Method
Semi-structured interviews with community pharmacists were conducted to gauge their perceptions regarding delivering depression screening services for older adults. Data analysis was conducted using an iterative, inductive approach. Key themes were identified, which were further explored and divided into subthemes. Subthemes were categorised as either barriers or facilitators. Each subtheme was mapped to the Capability, Opportunity, Motivation-Behaviour model by classifying whether they impacted pharmacists’ capability, opportunity, or motivation regarding depression screening.

Results
Fifteen pharmacists were interviewed, 12 of whom were female and 11 of whom practised in a metropolitan area. Four key themes were identified including: training needs, environmental factors, pharmacists’ roles, and organisational support, which were further divided into 13 subthemes. Three subthemes were mapped to Capability, seven to Opportunity and three to Motivation. Barriers included lack of resources and lack of remuneration, while facilitators included training, pharmacists’ accessibility, and rapport with consumers.

Conclusion
The findings of this study demonstrate that while community pharmacists found depression screening for older adults in community pharmacies to be an acceptable service, there remains a need for the development of funding schemes and standardised guidelines for pharmacist-delivered depression screening for older adults.
Predicting site-specific economic optimal nitrogen rate using machine learning methods and on-farm precision experimentation
Authors: de Lara Alfonso , Mieno Taro , Luck Joe D. , Puntel Laila A. 
Published: April 2023

AbstractApplying at the economic optimal nitrogen rate (EONR) has the potential to increase nitrogen (N) fertilization efficiency and profits while reducing negative environmental impacts. On-farm precision experimentation (OFPE) provides the opportunity to collect large amounts of data to estimate the EONR. Machine learning (ML) methods such as generalized additive models (GAM) and random forest (RF) are promising methods for estimating yields and EONR. Twenty OFPE N trials in wheat and barley were conducted and analyzed with soil, terrain and remote-sensed variables to address the following objectives: (1) to quantify the spatial variability of winter crops yield and the yield response to N using OFPE, (2) to evaluate and compare the performance of GAM and RF models to predict yield and yield response to N and, (3) to quantify the impact of soil, crop and field characteristics on the EONR estimation. Machine learning techniques were able to model wheat and barley yield with an average error of 13.7% (624 kg ha−1). However, similar yield prediction accuracy from RF and GAM resulted in widely different economic optimal nitrogen rates. Across sites, soil available phosphorus and soil organic matter were the most influential variables; however, the magnitude and direction of the effect varied between fields. These indicate that training a model using data coming from different fields may lead to unreliable site-specific EONR when it is applied to another field. Further evaluation of ML methods is needed to ensure a robust automation of N recommendation while producers transition into the digital ag era.
Digitisation and Sharing of Collections: Museum Practices and Copyright During the COVID-19 Pandemic
Authors: Klinowski Mateusz , Szafarowicz Karolina 
Published: April 2023

AbstractThis article concerns the conflict between copyright and museums’ digitisation and online sharing of collections. This issue has recently become particularly important in connection with the COVID-19 pandemic. The authors outline the concept of a virtual museum and present the most important copyright provisions in EU law that may create obstacles for cultural institutions in realising virtual counterparts. To perceive copyright as the main obstacle in the process of digitisation and online sharing of collections is not unusual. Hence, the article briefly presents legal framework of the European copyright applicable to such situations. The authors argue that although copyright offers a range of possibilities for museums interested in digitising their collections, at the same time it is responsible for a chilling effect, resulting in fear of potential infringement and liability. The authors conclude that the EU’s development of new legislation, coinciding with the need for digitisation and online sharing of cultural heritage caused by the pandemic, has favoured public interest at the expense of creators’ rights, but still lacks satisfactory legal tools for effectively allowing cultural institutions to digitise and share their collections.
Microstructural and Mechanical Characterization of Interfacial Phenomena Occurring in Brazing Ti-6AL-4V Alloy Using TiZrCuPd Amorphous Ribbons
Authors: Sypien Anna 
Published: April 2023

AbstractThe brazing technology with the proper choose of the filler metals should provide a solution for the major disadvantage of titanium alloys related to the problems of joining. This work concerns brazing of the Ti-6Al-4 V substrates with the originally amorphous TiCuZrPd ribbon. The TiCuZrPd filler enables proceeding of the brazing process below the melting temperature of the alloy, at about 880 °C. As the high quality of the filler/substrate interconnection remains substantial for the industrial application, the evolution of the mechanical and structural properties was studied while the induction and resistance heating were used to obtain Ti/Ti joints. The microstructure studies showed that at the interfaces obtained by both methods, the brazed zone was characterized by the uniform microstructure without defects such as separation of intermetallic phases or Kirkendall voids. In both cases, the interface consisted of three zones: upper diffusion zone, filler material zone and lower diffusion zone. It was also observed that regardless of the heating method used, the width of the reaction zone of the joints was similar, about 47 µm. On the other hand the ratio of the widths of the different zones was altered in dependence on the heating method used. The results showed that the brazing by induction heating increased the shear strength of the tested joints by two to three times, depending on the content of palladium in the filler metal. The highest value of shear resistance of approx. 650 MPa was noted for the joints obtained by induction heating at 850 °C.
Ein Überblick über ausgewählte standardisierte Instrumente zur Erfassung des Risikos von Entweichungen im Kontext von Lockerungsprognosen in forensisch-psychiatrischen Einrichtungen
Authors: Neumann Merten , Wittland Isabel , Schmitz Sophia Laura 
Published: April 2023

ZusammenfassungVollzugslockerungen stellen im Rahmen der forensisch-psychiatrischen Behandlung ein wichtiges Resozialisierungswerkzeug dar. Bei Entweichungen während Lockerungen handelt es sich angesichts der Anzahl der gewährten Lockerungsmaßnahmen um seltene Ereignisse. Trotz dessen gilt es, vor jeder Lockerungsgewährung das Risiko von Entweichungen einzuschätzen. Im Vergleich zur Bestimmung der allgemeinen Rückfälligkeit ist das Vorgehen bei der Lockerungsprognose bisher wenig erforscht und standardisiert. Auch wenn Instrumente zur Vorhersage erneuter Straftaten zur Lockerungsprognose eingesetzt werden können, stellt dies aufgrund der spezifischen Anforderungen an die Lockerungsprognose nur eine Übergangslösung dar. Die Etablierung eines lockerungsspezifischen Vorgehens ist wünschenswert. Im Rahmen des Artikels wird ein Überblick über 4 Instrumente zur Anwendung im Lockerungskontext gegeben, und bisherige Studienergebnisse zu diesen werden zusammengefasst: das Leave/Absconding Risk Assessment, das Short-Term Assessment of Risk and Treatability, das Booth Evaluation of Absconding Tool und die Waypoint Elopement Risk Scales. Erste Befunde zu den Risikoinstrumenten weisen weiteren Forschungsbedarf, insbesondere bei der Validierung außerhalb der Entwicklungsstichprobe und den Folgen der Anwendung, aus. Verbesserungen in der Risikoprogose können dabei zu einer weiteren Reduzierung der Entweichungsraten beitragen.
Developing a measurement scale of corporate socially responsible entrepreneurship in sustainable management
Authors: Gallardo-Vázquez Dolores , Herrador-Alcaide Teresa C. , de la Cruz Sánchez-Domínguez Juan 
Published: April 2023

AbstractTwo important lines of research come together in this paper: entrepreneurship and corporate social responsibility (CSR). Both stand out for their ability to contribute to sustainable development and generate competitive and social advantages. This study combined both approaches under the concept of CSR entrepreneurship (CSRE). A scale was developed to assess corporate socially responsible entrepreneurs’ traits in corporate contexts (i.e., CSRE-s). This quantitative measurement instrument was initially composed of 84 items, which were subjected to various validity and reliability tests. Exploratory factor and confirmatory factor analyses were conducted to identify the most significant determinant variables of individuals engaging in CSRE. The validated CSRE-s indicates that the corporate socially responsible entrepreneurship construct involves 6 entrepreneurship factors and 3 CSR dimensions—environmental, social, and economic—with 2 factors each (i.e., 6 factors), assessed by a total of 76 items. This research’s main contribution is the identification of CSRE features in entrepreneurs that together constitute an original, unique, and innovative framework for a sustainable development approach to entrepreneurship. The proposed conceptual model can be used to ensure the CSR values validated for the CSRE-s are incorporated into entrepreneurial training programs (i.e., universities), the public sector’s policies promoting entrepreneurship, and strategic business plans for expansion via entrepreneurship. The CSRE-s can be used to strengthen these three areas simultaneously, which should provide social advantages to all stakeholders via the sustainable management of entrepreneurial projects.
Risk Factors for Immune Checkpoint Inhibitor–Mediated Cardiovascular Toxicities
Authors: Yousif Laura I. , Screever Elles M. , Versluis Daniëlle , Aboumsallem Joseph Pierre , Nierkens Stefan , Manintveld Olivier C. , de Boer Rudolf A. , Meijers Wouter C. 
Published: April 2023

Abstract
Purpose of Review
Immune checkpoint inhibitors (ICIs) have improved the field of cancer, especially in patients with advanced malignancies. Nevertheless, cardiovascular immune-related adverse events (irAEs) with high mortality and morbidity have been observed, including myocarditis, pericarditis, and vasculitis. To date, only a few clinical risk factors have been described and are currently being investigated.

Recent Findings
In this review, we address the four most prevailing risk factors for cardiovascular irAEs. ICI combination therapy is a predominant risk factor for developing ICI-mediated myocarditis. Additionally, ICI combined with other anti-cancer treatments (e.g., tyrosine kinase inhibitors, radiation, chemotherapy) seems to increase the risk of developing cardiovascular irAEs. Other risk factors include female sex, pre-existing cardiovascular disease, and specific tumors, on which we will further elaborate in this review.

Summary
An a priori risk strategy to determine who is at risk to develop these cardiovascular irAEs is needed. Insights into the impact of risk factors are therefore warranted to help clinicians improve care and disease management in these patients.