bluuebunny/crossref_metadata_2025_split huggingface dataset:
Choral Activities of Anton Bruckner. Secular Vocal Works
Authors: Локотьянова Д.Е. 
Published: September 2023

Австрийский композитор Антон Брукнер (1824–1896) занял прочное место на «симфоническом олимпе» в мировой музыкальной культуре, а также еще при жизни снискал славу виртуозного органиста-импровизатора. Сегодня у слушателей вызывают восхищение и его церковные сочинения (масштабные вокально-инструментальные опусы Te Deum, Месса ми минор, мотеты Ave Maria, Locus iste, Os justi), вошедшие в историю хоровой музыки. Именно эти три сферы (Брукнер-симфонист, Брукнер-органист, Брукнер-церковный музыкант) чаще всего попадают в поле внимания исследователей. Светская же хоровая музыка композитора (как и его хоровая деятельность в целом) незаслуженно оказалась в тени. Между тем, данное направление всегда занимало важное место в жизни Брукнера: великий симфонист начинал свой путь как певчий монастырского хора, затем он был участником и руководителем хоровых коллективов, в том числе широко известного Liedertafel Frohsinn. Хоры (как церковные, так и светские) композитор писал на протяжении всей жизни; сохранилось более 40 светских вокальных (хоровых, ансамблевых) произведений, созданных мастером. Эти пьесы варьируются от кратких фанфар без сопровождения до развернутых по форме кантат. По ним сегодня можно судить об эволюции творческих поисков музыканта, о связях его хоровых сочинений с другими областями композиторского наследия. В статье впервые в отечественном музыкознании осуществляется попытка осветить хоровую практику Брукнера (включая создание его светских хоров) в историческом контексте.
The Austrian composer Anton Bruckner (1824–1896) has taken a strong place on the symphonic Olympus in the world musical culture, and even gained life fame both as a virtuoso and an organist-improviser. Today, listeners also admire his church choirs (for example, the famous vocal opuses Te Deum, Mass in E minor, motets Ave Maria, Locus iste, Os justi), which have become manuals in the field of choral music. It is these three areas (Bruckner as an organist, Bruckner as a symphonist, Bruckner as a church musician) that often draw attention of many researchers of his art. Secular choral music, however, like all his choral activities, was undeservedly in the shadow of the artist’s creative biography. Meanwhile, this area in the life of Bruckner always occupied an important place: the great symphonist began his career as a chorister of the monastery choir, then he was a member and leader of choral groups, including the well-known Liedertafel Frohsinn. The composer created (both church and secular) choirs throughout his life. Many secular vocal opuses (more than 40) created by the master have been preserved. These pieces range from short, unaccompanied mottos to extended cantatas. According to them, today one can judge the evolution of the musician’s creative endeavors, the musical ties with other areas of the composer’s heritage. This article is the first attempt in Russian musicology to highlight Bruckner’s choral activities (including creation of his secular choirs) in the historical context.
Fertilización foliar con nanopartículas de ZnO y su efecto en la producción, calidad biofísica y nutraceútica en frutos de nogal pecanero (Carya illinoinensis)
Authors: Estrada-Arellano Karla Lucero , Vázquez-Vázquez Cirilo , Betancourt-Galindo Rebeca , Muy-Rangel María Dolores , Valenzuela-Núñez Luis Manuel , García-Hernández José Luis , Gallegos-Robles Miguel Ángel 
Published: September 2023

El nogal pecanero (Carya illinoinensis) es uno de los cultivos más importantes de la Comarca Lagunera. La deficiencia de zinc (Zn) es uno de los principales problemas que limitan su productividad. La nanotecnología incluye materiales nutrimentales con los que se pueden sustituir fertilizantes convencionales con variado efecto en rendimiento, calidad biofísica y nutracéutica en el fruto. Los efectos de la aplicación foliar de nanopartículas de ZnO en nogal pecanero variedad Western fueron evaluados mediante dosis de Zn con los siguientes tratamientos: control, 4000 (ZnSO4), 2000 (nps ZnO), y 4000 (nps ZnO) mg L-1. El diseño experimental fue en bloques al azar con cuatro repeticiones. Las variables evaluadas en fruto y árbol fueron: rendimiento, número de nueces kg-1, largo y ancho de nuez, concentración de Zn en foliolos, ácidos grasos, proteína cruda, porcentaje de grasa y humedad. Se observó diferencia significativa en rendimiento y nivel de Zn en los foliolos, donde el mejor tratamiento fue 4000 mg L-1 de nanopartículas de ZnO, mientras que para la variable largo de nuez se observó diferencia significativa, siendo inferior el tratamiento de 4000 mg L-1 de ZnSO4. En las variables nutracéuticas, el contenido de ácidos grasos evaluado mediante el contenido de grasas saturadas (C16:0 y C18:0) mostró cambios altamente significativos, siendo el tratamiento con la dosis de 4000 mg L-1 de nanopartículas el que tuvo mayor porcentaje. Los ácidos grasos insaturados (C18:1 y C18:3) mostraron diferencias significativas, siendo los tratamientos evaluados con nanopartículas los que tuvieron un porcentaje inferior. El contenido de proteína también mostró diferencias altamente significativas, siendo el tratamiento control y el químico a base de ZnSO4 los tratamientos superiores. Las nanopartículas pueden ser usadas para mejorar el rendimiento y abastecer el contenido de Zn al cultivo, pero la calidad de fruto se ve afectada desde el punto de vista nutricional.
Upaya Pemberdayaan Keluarga dalam Pencegahan Penyimpangan Perkembangan Melalui Edukasi Stimulasi Tumbuh Kembang Anak
Authors: NIKMAH NURUN , Zainiyah Hamimatus 
Published: September 2023

Stimulasi adalah kegiatan merangsang kemampuan dasar anak umur 0 sampai 6 tahun agar anak tumbuh dan berkembang secara optimal. Simulasi yang tepat akan merangsang otak berita sehingga perkembangan kemampuan gerak, bicara dan bahasa, sosialisasi dan kemandirian pada balita berlangsung optimal sesuai dengan umur anak. Kegiatan mencegah penyimpangan perkembangan anak, maka perlu dilakukan kegiatan yaitu peningkatan pengetahuan ibu tentang stimulasi tumbuh kembang anak.
Berlatarbelakang fenomena di atas, diharapkan adanya sebuah peningkatan pengetahuan ibu tentang stimulasi pada anak usia 24-36 bulan. Metode yang dilakukan dalam pengabdian masyarakat ini yaitu dengan: Pemberian Leaflet dan Penyuluhan tentang Stimulasi perkembangan motorik halus pada balita usia 24-36 bulan. Hasil pengabdian ini didapatkan bahwa Pengetahuan ibu hamil sebelum dilakukan penyuluhan yaitu pengetahuan baik 2 (6,66%), cukup 11 (36,67%), dan kurang 17 (56,67%). Pengetahuan ibu hamil setelah dilakukan penyuluhan yaitu pengetahuan baik 21 (70,00%), cukup 9 (30,0%), dan kurang 0 (0%). Terjadi peningkatan pengetahuan ibu, yaitu dari pengetahuan baik sebanyak 6,66% menjadi 70,00%).

Kata kunci— Perkembangan, stimulasi, motorik halus, Anak, Balita
Penguatan Profil Pelajar Pancasila Melalui Pelatihan Sediaan Celup Herbal Pada Kelas X Passion SMAM 1 Gresik
Authors: Nasyanka Anindi Lupita , Na'imah Janatun , Ratnasari Diah 
Published: September 2023

Pelajar Pancasila adalah perwujudan pelajar Indonesia sebagai pelajar sepanjang hayat yang memiliki kompetensi global dan berperilaku sesuai dengan nilai-nilai Pancasila. Dalam perwujudan profil pancasila tersebut, salah satunya menggali potensi lokal yang ada didaerahnya dan dikembangkan menjadi produk yang memiliki nilai jual dan bernilai. Salah satu ciri utama yakni berfikir kritis dan kreatif. SMA Muhammadiyah 1 Gresik merupakan Gresik salah satu sekolah dengan visi dan misi yang mendukung pelajar pancasila melalui program kelas passion. Produk yang diminati dimasa pandemi Covid-19 berupa sediaan celup herbal salah satunya adalah teh. PKM. Pelaksanaan kegiatan Pengabdian kepada masyarakat ini berlangsung selama tiga minggu yaitu 25 Februari 2022-27 Maret 2023 di Kelas X Passion Kesehatan SMA Muhammadiyah 1 Gresik. Jumlah peserta PKM sebanyak 32 Siswa. PKM terdiri dari beberapa tahapan pelaksanaan, tahap pertama mahasiswa akan diberi pemaparan materi terkait pemanfaatan tanaman dan formulasi kemudian akan dilakukan quiz untuk mengukur pemahaman siswa sebelum praktek pembuatan. Kemudian satu kelas akan dibagi 4 kelompok untuk membuat jurnal pembuatan teh. Siswa diberi waktu 2 minggu untuk melakukan pembuatan teh dan hasilnya dipresentasikan untuk dipilih sebagai produk yang akan dipamerkan dalam gelar karya passion di SMAM 1 Gresik. Kegiatan pengabdian masyarakat kepada siswa kelas X Passion kesehatan SMA Muhammadiyah 1 Gresik melalui rangkaian pelatihan sediaan celup berjalan lancar dengan semua nilai siswa diatas 50% pengetahuan terhadap pembuatan sediaan celup herbal maupun peningkatan ketrampilannya.
Solubility data and solubility parameters of barnidipine in different pure solvents
Authors: Peña-Fernández Mª Ángeles , Spanò Gaia , Torres Pabón Norma Sofía , Martínez Fleming 
Published: September 2023

Introduction: Solubility studies and obtaining physicochemical data on drugs in pure solvents belonging to different chemical classes are key to developing new drug formulations. In this work, Hansen partial solubility parameters (HSP) were calculated to assess the miscibility and intermolecular interactions of barnidipine in seventeen pure solvents. The comparison of the results obtained with the theoretical values ​​calculated according to the structure of barnidipine, were valuable to analyse the influence of the solute-solute, solute-solvent relationships of the additive contribution groups, on the chemical and physical properties of this molecule with the solvents of different polarity tested, to provide relevant information highly useful in the pharmaceutical industry.
Method: Equilibrium barnidipine solubilities in mono-solvents was determined using the classical shake-flask method, followed by UV-spectrophotometric analysis at 298.15 K. The partial solubility parameters were calculated by applying theoretical group contribution methods, proposed by Hoftyzer-Van Krevelen and Fedors. The KAT-LSER model was used to investigate the effect of solvent based on the concept of linear solvation energy relationships. The mole fraction was obtained from the densities of the solutions. Solid-phase analyses were made by calorimetry differential scanning.
Results: The modification introduced in the extended Hansen method, that is, the use of lnX2 as the dependent variable, provided excellent results. The highest solubility values have been found in polar solvents. It is observed that solvent-solvent and solute-solvent intermolecular interactions through hydrogen bonds and van der Waals forces, significantly influence drug solubility.
Conclusions: The affinity between barnidipine and each one of the selected solvent was evaluated by using HSP. Results showed that HSP could be well used to analyse drug solubility in particular solvents. Barnidipine is easier to dissolve in solvents with shorter carbon chains and higher polarity.
Efficacy of Different Statins Among Newly Diagnosed Dyslipidemic Patients in Dhulikhel Hospital
Authors: Humagain Sanjaya , Pathak Surya Raj , Koju Rajendra Prasad 
Published: September 2023

Background and Aims: Cardiovascular Disease is the leading cause of death. Prevention of cardiovascular disease is the major aim of treatment of anyone who has risk. Dyslipidemia lies in the center of cardiovascular disease risk. Not only there is difference in pattern of dyslipidemia and response to statins in different ethnic groups, there is difference in mortality due to cardiovascular disease in different race and ethnic group. Atorvastatin and Rosuvastatin are the first line statins. This study is carried out to see how our population responds to these statins in terms of change in lipid profile.
Methods: It is a real world observational study. Dyslipidemia patients requiring statins were given either Atorvastatin 10 mg or Rosuvastatin 5 mg according to physician’s discretion. Demographic profile and baseline lipid was recorded. Lipid profile was again recorded after 3 to 4 months of treatment.
Result: Out of 343 enrolled only 304 data was analyzed. Total cholesterol decreased by 21.9 % (p = 0.002) in Atorvastatin group and by 22.9 % (p= 0.002) in Rosuvastatin group. Low Density Lipoprotein (LDL) decreased by 22.3 % (p = 0.004) in Atorvastatin group and 21.5% (p=0.005) in Rosuvastatin group. There was no significant difference between two groups.
Conclusion: Both Atorvastatin 10 mg and Rosuvastatin 5 mg can reduce the lipids significantly in our population. There is no difference in using Atorvastatin 10 mg or Rosuvastatin 5 mg. However, reduction was only mild to moderate with the given doses.
Prevalence of anemia and associated factors among patients with heart failure at Birat Medical College Teaching Hospital
Authors: Bista Madhab , Mehta Ram Kumar , Parajuli Surya B. , Shah Prashant 
Published: September 2023

Background and Aims: Anemia is a frequently encountered comorbid illness in heart failure and is associated with poor clinical outcomes. There are limited studies done in Nepal to evaluate its prevalence among patients diagnosed with heart failure. Hence, this study was aimed to find out the prevalence of anemia and associated factors among patients with heart failure at Birat Medical College Teaching Hospital.
Methods: A hospital based cross sectional study was conducted from 1st July 2022 to 30 February 2023 among consecutively selected 100 patients at Birat Medical College Teaching Hospital. Socio-demography, clinical features and laboratory parameters to evaluate anemia were obtained. Ethical clearance was taken from the Institutional Review Committee of institute. Collected data was entered in Microsoft Excel and analyzed by Statistical Package for Social Sciences version 23. Frequency, mean, percentage were calculated and chi square test at 0.05% level of significance was used to find the association.
Results: The prevalence of anemia was 65%. Out of 100 patients, majority had iron deficiency anemia (40%), followed by anemia of chronic disease (10%). Thirty three percent had iron deficiency without anemia. Female patients 36(75%) and patients with chronic obstructive pulmonary disease (COPD) 15(93.8%) had significantly higher prevalence of anemia (p value <0.05).
Conclusions: Nearly two third of heart failure patients had anemia among which iron deficiency anemia was the commonest. Female and patients with COPD had higher prevalence of anemia.
A Decade of Experience in the use of 13-Valent Conjugated Polysaccharide Pneumococcal Vaccine in Russian Federation
Authors: Briko N. I. , Korshunov V. A. , Lobzin Ja. V. , Namazova-Baranova L. S. , Rudakova L. V. , Simonova E. G. 
Published: September 2023

Pneumococcal infection remains a significant global health problem, and vaccination is the main measure for its prevention. To date, the period of use of pneumococcal conjugated polysaccharide vaccines in Russia exceeds 14 years, and 13-valent conjugated polysaccharide pneumococcal vaccine (PCV13) - more than 10 years. During this time, extensive experience has been accumulated in the use of this type of vaccines, and many studies have been carried out to evaluate their effectiveness and safety.The purpose of this review is to summarize the experience of using PCV13 in Russian Federation with an assessment of its epidemiological and clinical effectiveness. A search was made for scientific publications devoted to the study of the epidemiological efficacy, the safety as well as cost-effectiveness of PCV13 use in Russian Federation. The review included original studies published in Russian journals. The results of the studies carried out indicate the efficacy and safety of PCV13 for both adults and children. The effectiveness of immunization of children at risk (premature, suffering from congenital pathology, having chronic diseases and often ill) was demonstrated, the need and safety of the timely start of vaccination (from 2 months of age) of newborns was shown, the possibility of its combination with immunization against other infections within the framework of the national vaccination schedule, the importance of following the recommended vaccination schedule in accordance with the age of the child. The effectiveness of vaccination of adults suffering from chronic diseases has been shown both in terms of preventing the aggravation of the course of the underlying pathology and reducing the risk of pneumonia. Positive experience has been gained in immunizing adults from occupational risk groups - medical workers, conscripts and persons exposed to a harmful production factor and having occupational lung diseases. The conducted studies have shown a high cost-effectiveness of PCV13 vaccination, however, with any changes in price and epidemiological parameters, it is necessary to clarify the economic feasibility of vaccination under the changed conditions. Taking into account the positive experience gained in immunization, it seems appropriate to further maintain a high level of vaccination coverage of the child population, expanding risk groups among the adult population subject to vaccination against pneumococcal infection within the framework of the National Immunization Schedule, taking into account its epidemiological, clinical and economic efficiency.
Features of a Systematic Approach to the Prevention of Healthcare-Associated Infections in the Russian Federation and abroad
Authors: Davydova M. A. , Bryukhanova G. D. , Gorodin V. N. 
Published: September 2023

Relevance. Health care-associated infections (HAIs) are one of the global problems of modern healthcare with a negative trend in the growth of this pathology throughout the world, which is due to a complex of reasons, among which the resistance of pathogens of hospital infections to antimicrobials is important, as well as gaps in organization of epidemiological surveillance due to a number of objective and subjective factors (complication of technologies and expansion of the practice of invasive medical interventions, turnover and shortage of personnel in medical institutions, etc.).The purpose of the work is to study the experience of organizing measures for the prevention of HCAI from the standpoint of a systematic approach in Russia and in foreign countries that have the best practices in this area. The purpose of the work is to study the experience of organizing measures for the prevention of HCAI from the standpoint of a systematic approach in Russia and in foreign countries that have the best practices in this area.The results are based on the study of the basic principles of the system approach, its tools, functional organization and universalization, the use of a comprehensive analysis in relation to different areas of medical activity and types of medical care, the sequence of development and implementation of new methods in Russian and foreign experience in the implementation of epidemiological surveillance for HCAI. Problems in the field of organization and practical implementation of preventive measures to prevent the occurrence of HCAI have been identified, and urgent tasks for improving the epidemiological safety of medical activity have been identified.Conclusion. Differences were noted in approaches to the prevention of HAIs in Russia and abroad, concerning the resource provision of molecular biological monitoring of HAI pathogens, as well as the features of teamwork, targeted communication in medical teams and in explanatory work, as well as the implementation of training programs for relatives to care for patients with HAI. Measures are proposed to increase the commitment of medical personnel and collectives in general, other employees of medical organizations to epidemiologically safe skills in their professional activities, to develop patient education programs for personal prevention of HCAI.
Molecular Surveillance of Natural Focal Diseases Causative Agents in the Stavropol Territory in 2016–2021
Authors: Chekrygina E. V. , Volynkina A. S. , Zaitseva O. A. , Lisitskaya Ya. V. , Tishchenko I. V. , Gnusareva O. A. , Rostovtseva D. V. , Vasilenko E. I. , Tkachenko N. O. , Vasilyeva O. V. , Purmak K. A. , Solomashchenko N. I. , Kulichenko A. N. 
Published: September 2023

Relevance. Molecular surveillance, aimed at obtaining up-to-date information on the genetic variants of pathogens circulating in the studied region, is an important element of the surveillance of natural focal infections (NFIs). The Stavropol Territory is one of the main recreational regions in the Russian Federation; it is endemic for a number of NFIs, including: Crimean-Congo hemorrhagic fever (CCHF), Q fever, tularemia, Lime disease, etc.The aim of the work is is genomic profiling of NFIs causative agents circulating in the Stavropol Territory in 2016-2021.Materials and methods. Microbial strains and samples of field and clinical material containing genomic DNA/RNA of pathogens were used as material for the study. Genetic typing of strains and isolates of DNA/RNA NFIs causative agents was performed by MLVA (Francisella tularensis and Coxiella burnetii) and genome fragment sequencing (Crimean-Congo hemorrhagic fever virus, West Nile virus, orthohantaviruses, Borrelia burgdorferii s.l., Ricckettsia sp.).Results. As a result of molecular genetic typing in the ST in 2016-2021 confirmed circulation of strains of F. tularensis of genetic subgroups B.I, B.III, B.VI, genetically identical strains of C. burnetii (VNTR-профиль 4-6-6-4-7-6-3-12-3-11), rickettsia belonging to 5 species: R. raoultii, R. aeschlimannii, R. slovaca, R. massiliae, R. helvetica , Borrelia belonging to the species: B. afzelii, B. garinii, B. miyamotoi, B. bavariensis, B. lusitaniae, B. valaisiana, RNA isolates of the CCHF virus of the Europe-1 and Europe-3 genetic lines, Tula orthohantaviruses, West Nile virus genotype 2. For the first time on the territory of the CT, in insectivore lung samples, RNA isolates of orthohantavirus genetically close to Camp Ripley virus (RLPV) were detected.Conclusions. New data have been obtained on the distribution of genetic variants of NFIs causative agents in the S, also in the recreation areas. Genetic structure of the population of NFIs causative agents in the ST in 2016-2021 did not change significantly, which indicates the relative stability of the natural foci of NFIs in the region.