bluuebunny/crossref_metadata_2025_split huggingface dataset:
Type of arrhythmias and the risk of sudden cardiac death in dialysis patients: a systematic review and meta-analysis
Authors: Chander Subhash , Aamir Ahmad Bin , Latif Rabia , Parkash Om , Sorath F. N. U. , Tan Sam , Lohana Abhi Chand , Shiwlani Sheena , Nadeem Mohammed Yaqub 
Published: January 2025

Abstract

Background
Patients on long-term dialysis for end-stage kidney disease have a high mortality rate, predominantly due to sudden cardiac death (SCD), which is associated with an increased risk of arrhythmias compared to the general population. Thus, the current systematic review and meta-analysis aimed to investigate the incidence of SCD among dialysis patients at risk of arrhythmia.

Methods
This systematic review and meta-analysis followed the PRISMA guidelines. PubMed, Cochrane Library, Google Scholar, Medline, and Europe PMC were searched for articles meeting our inclusion criteria. Studies with risk assessment of arrhythmias and the incidence of SCD in dialysis patients were considered for inclusion. Effect size from eligible studies was pooled using a random effects model and restricted maximum likelihood estimation. Heterogeneity was quantified using the I
2 statistic, and the risk of publication bias was evaluated by visually inspecting funnel plots.

Results
Our search strategy yielded 5861 studies, of which 1960 duplicate entries were removed in the prescreening stage, 3326 were excluded after title/abstract screening, and 519 after full-text screening for not meeting our inclusion criteria. Finally, 11 studies were included in the analysis, and two more were selected from the bibliography list of previous reviews. Eight included studies were randomized controlled trials, and five were cohort studies, which provided a pooled population size of 12,611 dialysis patients for the meta-analysis, which indicated a significantly larger effect size of arrhythmia [Cohen’s d = 110.38 (95%CI 42.72–178.05), p = 0.0]. Visual assessment of the funnel plot indicated no publication bias.

Conclusion
SCD remains a significant public health concern, particularly in patients undergoing dialysis. Meta-analysis results show that bradyarrhythmia is a common arrhythmic condition leading to SCD; however, other arrhythmias should also be considered.
Approach to Lipid Management in the Patient With Diabetes
Authors: Kim Stephanie , Subramanian Savitha 
Published: January 2025

Abstract
Diabetes is associated with increased atherosclerotic cardiovascular disease (ASCVD) risk, a leading cause of morbidity and mortality. Disordered lipid metabolism is a major contributor to ASCVD risk in diabetes. Dyslipidemia in type 2 diabetes is characterized by hypertriglyceridemia, low high-density lipoprotein cholesterol and the presence of small, dense low-density lipoprotein particles. Statins have demonstrated longstanding benefit for reducing ASCVD risk in individuals with diabetes. Newer agents for add-on therapies to statins are now available for additional cardiovascular risk reduction. In this clinical overview, we review the pathogenesis of dyslipidemia in both type 1 and 2 diabetes and provide an update on the management of lipids in the individual with diabetes. We discuss the importance of appropriate risk stratification and individualized treatment selection and the need to avoid therapy inertia to mitigate cardiovascular risk. We also address lipid-related effects of glycemic-lowering therapies.
Knee Extensor and Flexor Force Control after ACL Injury and Reconstruction: A Systematic Review and Meta-Analysis
Authors: SCHWARTZ AVA L. , KOOHESTANI MOEIN , SHERMAN DAVID A. , STOCK MATT S. , NORTE GRANT E. 
Published: January 2025

ABSTRACT

Purpose
Reduced force control after anterior cruciate ligament (ACL) injury and reconstruction may contribute to poor function. Various metrics (linear and nonlinear) have been employed to quantify force control. The aims of this review were to synthesize evidence assessing knee extensor and flexor force control after ACL injury (ACLD) or reconstruction (ACLR) and to investigate the potential effects of injury management (e.g., surgery, graft type), mode of contraction (e.g., isometric, isokinetic), and speed and intensity of contraction.

Methods
We searched six databases for studies assessing knee extensor or flexor force control in individuals with ACLD or ACLR using a linear or nonlinear analysis method and comparing to the uninvolved limb or an uninjured control. Two independent reviewers assessed potential studies for inclusion and quality. Primary random effects meta-analyses were simultaneously separated by muscle, injury management, analysis method, and comparator.

Results
Twenty-seven studies were included. When assessed via linear methods, greater variability in knee extensor force (i.e., reduced force control) was observed only in comparison to uninjured controls (ACLD: P = 0.03, Hedges’ g = 0.22, [95% confidence interval CI 0.02–0.42]; ACLR: P = 0.01, Hedges’ g = 0.23, [95% CI = 0.05–0.41]). When assessed via nonlinear methods, lesser regularity of knee extensor force control (i.e., reduced force control) was observed in comparison to the uninvolved limb (ACLD: P = 0.008, Hedges’ g = 0.44, [95% CI = 0.11–0.76]; ACLR: P < 0.00001, Hedges’ g = 0.75, [95% CI = 0.61–0.88]) and uninjured controls (ACLD: P = 0.002, Hedges’ g = 0.44, [95% CI = 0.16–0.72]; ACLR: P < 0.00001, Hedges’ g = 0.69, [95% CI = 0.55–0.82]). Funnel plot data suggested a potential risk of bias.

Conclusions
Moderate-to-strong evidence indicates impaired knee extensor force control after ACLR in comparison to uninjured controls, regardless of analysis type. Nonlinear analyses detected more and greater force control differences, thus appearing to be more sensitive and highlighting a need for a standardized, clinically accessible methodology. These results may be partially explained by the neuromuscular mechanisms underlying motor control.
A Machine Learning-Assisted Decision-Making Methodology Based on Simplex Weight Generation for Non-Dominated Alternative Selection
Authors: de Moraes Matheus Bernardelli , Coelho Guilherme Palermo , Bratvold Reidar B. 
Published: January 2025

In multiobjective decision-making problems, it is common to encounter nondominated alternatives. In these situations, the decision-making process becomes complex, as each alternative offers better outcomes for some objectives and worse outcomes for others simultaneously. However, DMs still must choose a single alternative that provides an acceptable balance between the conflicting objectives, which can become exceedingly challenging. To address this scenario, our work introduces a decision-making framework aimed at supporting such decisions. Our proposed framework draws upon concepts from the field of Multi-Criteria Decision Making, and combines a novel simplex-like weight generation method with expert insights and machine learning data-driven procedures to establish an intuitive methodology that empowers DMs to select a single alternative from a range of alternatives. In this paper, we illustrate the effectiveness of our methodology through an example and two real-world decision cases from the oil and gas industry, each involving 128 alternatives and five distinct objectives. Funding: This work was supported by Equinor [Grant 2017/15736-3]; Fundação de Amparo à Pesquisa do Estado de São Paulo [Grant 2017/15736-3].
Pegaspargase induced multiple organ failure with acute lymphoblastic leukemia: A case report
Authors: Bao Su-Xia , Yuan Xiao-Ling , Yan Lei , Xu Jie 
Published: January 2025

BACKGROUND
The introduction of pegaspargase has greatly advanced the treatment of acute lymphoblastic leukemia (ALL). In the literature, only one case of pegaspargase-induced multiple organ failure has been reported, and the patient died due to multiple organ failure.
CASE SUMMARY
Herein, we present a rare case of a 40-year-old man with ALL who developed multiple organ failure after treatment with pegaspargase. The patient had two rare phenomena reflecting poor prognosis, including the discrepancy between clinical manifestations and liver function and persistently low alpha-fetoprotein (AFP) levels from subacute liver failure. However, the patient was successfully treated using a multidisciplinary team approach.
CONCLUSION
This is the first case report of successful treatment of pegaspargase-induced multiple organ failure. The findings emphasize the importance of a multidisciplinary team approach in treating pegaspargase-induced multiple organ failure.
THE IMPERATIVE OF REGULATING BODY-WORN CAMERAS FOR THE INDONESIAN POLICE FORCE
Authors: Tantimin Tantimin , Alhakim Abdurrakhman 
Published: January 2025

Despite global adoption, Indonesia's criminal justice system lags in utilizing body-worn cameras (BWCs), hindered by the absence of a regulatory framework. This disparity complicates efforts to curb police misconduct, ensure accountability, and protect individual rights. The study underscores the urgency of promoting transparency and rebuilding public trust in law enforcement. It identifies a disconnect between the conceptual need for BWCs and the lack of normative support in Indonesia. Key challenges include oversimplified data classification, inadequate mechanisms for handling biometric data, and a lenient police code of ethics on evidence management. These issues pose significant challenges to the BWCs’ effectiveness, undermining their potential to enhance accountability. By addressing these issues, BWCs can realize their full potential in contributing to a more accountable and ethical data protection standards.
Multilingualism, translanguaging, and education in the Vaupés, Northwest Amazonia: dynamics of language use, and language loss
Authors: Palacio Hernandez Ricardo , Bolaños Katherine 
Published: January 2025

Abstract
This paper examines translanguaging interactions in the multilingual area of the Vaupés, northwest Amazonia. After providing a brief overview of the Vaupés’ multilingual landscape-highlighting its social and linguistic diversity, as well as its distinct identities- we present evidence of multilingual interactions collected during fieldwork using ethnographic and linguistic documentation methods. This data is further illustrated through comments on grammatical aspects and unique linguistic features of certain local languages, showcasing how these languages differ from Spanish, the vehicular language used in the formal education of indigenous populations. Our discussion is framed within the context of epistemic injustice and education, emphasizing the importance of incorporating indigenous epistemologies and ecouraging the pedagogical use of translanguaging practices in educational settings. We argue that the traditional model of ‘castellanización’ (or ‘Spanish-ization’) offered by the Colombian State to school programs in the Vaupés, invisibilizes (if not, negates) the cultural, social and spiritual particularities of indigenous individuals and societies in the area. Furthermore, this educational Spanish-ization model fails to acknowledge the structural linguistic complexities and the linguistic interactions (translanguaging) embedded in everyday life, resulting in social and cognitive disadvantages in the student population.
Do Firm-Level Shocks Generate Aggregate Fluctuations? A Cross-Country Analysis
Authors: Lin Shuheng , Pérez Francisca 
Published: January 2025

Abstract
This paper tests the granular hypothesis introduced by Gabaix (2011. “The Granular Origins of Aggregate Fluctuations.” Econometrica 79 (3): 733–72) in the US, Germany, Canada, France, Japan, and the UK. We find that firm-level idiosyncratic shocks significantly impact aggregate fluctuations in only three of the six countries analyzed. Compared to the US, Japan and Germany, the UK, France, and Canada show greater granularity, but also a negligible firm-level contribution to aggregate volatility. Additional results look at the role of the transportation sector as a potential driver of granular effects in the US, Germany and Japan.
Suitability of different sealer media for moisture uptake tests of wood
Authors: Nopens Martin , Ohlmeyer Martin , Brischke Christian 
Published: January 2025

Abstract
Partial sealing of surfaces of test specimens is essential for determining direction-dependent water absorption of wood. Preliminary tests with existing sealants showed limited applicability particularly for standardisation. The objective was to find new sealer material. The suitability of four different materials (bitumen, polyurethane acrylic resin, liquid rubber spray, aluminium tape) was investigated. Their sorption capacity and water vapor tightness were determined with an automated sorption balance. The experiments revealed that most of the used sealers were not diffusion-tight or showed outgassing. Only the aluminum tape seems to be suitable.
Some results on Kenmotsu space forms
Authors: B Shanmukha , Abdallah Suhad Ali Osman , El-Gawaad N. S. Abd 
Published: January 2025

Abstract
The object of the present paper is to study Kenmotsu space forms satisfying pseudosymmetric, Ricci-pseudosymmetric and locally-ϕ-symmetric. Further we study
the quasi-conformal flat and quasi-conformal semisymmetric Kenmotsu space forms.
Discontinuity of the noun phrase in Roman statutes from the Republican period
Authors: Spevak Olga 
Published: January 2025

Abstract
This article discusses discontinuity of the noun phrase, i.e. the separation of adjectival, genitival, or other modifiers from their head noun in Latin legal texts from the Republican period. Despite the common view that discontinuity, often termed ‘hyperbaton’, is a stylistic device, the study shows that discontinuity is also found in legal texts. Discontinuity mainly occurs with relative and indefinite pronouns as well as with genitival modifiers, and it is pragmatically motivated. Additionally, noun and prepositional phrases are regularly split by the enclitic coordinators -que ‘and’ and -ve ‘or’ in legal texts.
Qui pro quo in Plautus’ grammar
Authors: Zheltova Elena V. 
Published: January 2025

Abstract

Qui pro quo is an excellent means of creating a comic effect in ancient drama, particularly in the comedies of Plautus. In this study, qui pro quo is metaphorically transferred from drama to grammar and applied to the phenomenon of substituting one grammatical category for another. First, I will introduce the notion of canonical and non-canonical grammatical meaning, which is crucial for the idea of grammatical qui pro quo. The concept of oppositions and neutralisation will be proposed as a scientific hypothesis to explain why language employs this strategy. Then I will analyse the qui pro quo technique within the categories of tense and mood (e.g., Praesens pro futuro, Futurum pro praesente, Imperfectum pro praesente, Indicativus pro coniunctivo, Infinitivus pro indicativo, Indicativus pro imperativo, etc., nine patterns in all). After considering verbal categories, the sentential qui pro quo will be observed in five types of sentences with different illocutionary force. Finally, the effect of the phenomenon in question on the insubordinate ut-, si-, and quasi-clauses will be shown. In the end, I will summarise the findings and explain the mechanism of grammatical qui pro quo as manifestation of the neutralisation principle.
Comparing achievability and reproducibility of pulsed wave doppler and tissue doppler myocardial performance index and spatiotemporal image correlation annular plane systolic excursion in the cardiac function assessment of normal pregnancies
Authors: Hagai Avnet , Anna Erenbourg , Samantha Thomas , Simcha Yagel , Alec Welsh 
Published: January 2025

Abstract

Objectives
Multiple techniques have been proposed for functional fetal cardiology, including pulsed-wave (PW) and tissue Doppler imaging (TDI), Myocardial Performance Index (MPI), annular plane systolic excursion (TAPSE/MAPSE) and spatiotemporal image correlation (STIC). We aimed to compare these techniques’ achievability and reproducibility to determine their clinical utility for each cardiac side.

Methods
Uncomplicated pregnancies from 22 to 39 weeks were recruited and images and volumes stored for offline analysis. PWD-MPI values were calculated using previously demonstrated automation algorithms, and the remaining volumes were evaluated by two experienced operators.

Results
79 women were scanned generating 222 volumes, with high achievability (>86 %) for all three modalities on both cardiac sides; highest for TAPSE/MAPSE (94 %). Repeatability (ICC) on the right side of the heart was highest for TAPSE (inter-observer 0.86; intraobserver 0.73), compared to PWD-MPI (0.69) and TDI-MPI (0.83). For the left side, repeatability was high for both PWD-MPI (0.80) and TDI-MPI (0.86) though low for MAPSE (inter-observer 0.7, intra-observer 0.69). There was poor correlation between PWD-MPI and TDI-MPI values.

Conclusions
TAPSE appears most reliable for evaluation of right heart function, compared to PWD-MPI for the left. As TDI-MPI correlates poorly with PWD-MPI, the latter appears to be the functional tool of choice.
Antepartum multidisciplinary approach improves postpartum pain scores in patients with opioid use disorder
Authors: Yang Tiffany , Stetler Emily , Garretto Diana , Herrera Kimberly , Garry David , Heiselman Cassandra 
Published: January 2025

Abstract

Objectives
Pregnancies affected by opioid use disorder (OUD) face difficulties with postpartum pain control. This study aims to determine if prenatal anesthesia consultation for patients on medication for opioid use disorder (MOUD) affects maternal postpartum pain control.

Methods
This is a retrospective cohort study of pregnant patients diagnosed on MOUD who received prenatal care and delivered at a single academic institution between January 2017 and July 2023. Subjects were divided into those who received prenatal anesthesia consultation and those who did not. Severe pain (numerical rating scale 0–10) was defined as score≥7. Statistical analysis was performed using Chi-square, Mann-Whitney U, and multivariable logistical regression tests with significance defined as p<0.05.

Results
The cohort included 359 women on MOUD. Of these, 17.8 % (n=64) received anesthesia consultation and 82.2 % (n=295) did not. Factors found associated with receiving anesthesia consultation were prenatal care with an obstetric provider trained in maternal OUD (p<0.01), psychiatric diagnosis (p<0.01) and higher number of prenatal care visits (10.12 vs. 8.99, p=0.007). When comparing pain scores in the first 24 h postpartum, patients with prenatal anesthesia consultation had statistically significant lower rates of severe pain compared to those who did not (25 vs. 44.7 %, p=0.004). Anesthesia consultation (OR 0.34) and cesarean section (OR 2.81) were independent predictors of severe postpartum pain in the first 24 h after delivery.

Conclusions
Patients on MOUD who received antenatal anesthesia consultation report lower postpartum pain scores than those without consultation, which supports that multidisciplinary care for pregnant patients with OUD may help the postpartum experience.
Analysis of the effect of ALA-PDT on macrophages in footpad model of mice infected with Fonsecaea monophora based on single-cell sequencing
Authors: Chen Wenyi , Wu Xuelin , Yaqoob Muhammad Danish , Liu Kangxing , Hu Yanqing , Ke Xiuling , Hu Yongxuan 
Published: January 2025

Abstract
Chromoblastomycosis (CBM) is a chronic neglected fungal disease that causes serious damage to the physical and mental health of patients. 5-Aminolevulinic acid photodynamic therapy (ALA-PDT) has garnered significant attention in the recent era for the treatment of CBM and has exhibited promising effects in several clinical case reports. We established a mice footpad infection model with Fonsecaea monophora and analyzed the impact of PDT treatment on the immune response of macrophages using single-cell sequencing. The results showed that infection of the mouse footpad skin with F. monophora results in an increase in inflammatory cells, primarily mononuclear-macrophages, with the activation of complement and enhancement of cell chemotaxis, leading to upregulation of anti-infection-related pathways. After ALA-PDT treatment, the number of inflammatory cells decreased, while macrophages upregulated the expression of antigen-recognition-related genes, enhancing phagocytosis and autophagy-related biological functions.
Salutogenic Effects of Greenspace Exposure: An Integrated Biopsychological Perspective on Stress Regulation, Mental and Physical Health in the Urban Population
Authors: Varadarajan Suchithra , Herchet Marilisa , Mack Matthias , Hofmann Mathias , Bisle Ellen , Sayer Emma , Kolassa Iris-Tatjana 
Published: January 2025

Abstract
Globally, urbanization is associated with increased risk for physical and mental diseases. Among other factors, urban stressors (e.g. air pollution) are linked to these increased health risks (e.g. chronic respiratory diseases, depression). Emerging evidence indicates substantial health benefits of exposure to greenspaces in urban populations. However, there is a need for an overarching framework summarizing the plausible underlying biological factors linked to this effect, especially within the context of stress regulation. Therefore, by outlining the effects of greenspace exposure on stress parameters such as allostatic load, oxidative stress, mitochondria, and the microbiome, we conceptualize an integrated biopsychological framework to advance research into the salutogenic and stress-regulatory potential of greenspace exposure. In addition, we discuss the understudied potential health benefits of biogenic volatile organic compounds. Our perspective highlights the potential for innovative greenspace-based interventions to target stress reduction, and their prospect as add-ons to current psychotherapies to promote mental and physical health in urban populations.
Fluorescence analysis of wood chips and their constituents
Authors: Schneckenburger Herbert , Weber Katharina , Holderied Kevin , Janßen Hauke , Fischer Steffen , Wolfinger Tobias , Kantlehner Willi 
Published: January 2025

Abstract
Micro-spectral analysis and fluorescence decay experiments of beech and oak chips as well as their main constituents lignin and cellulose are reported. While the lignin spectrum shows two fluorescence bands of almost identical intensity around 500 nm and 560 nm, the cellulose spectrum is dominated by a band around 500 with a less pronounced shoulder at 560 nm, whose intensity increases with the amount of residual lignin. Fluorescence decay kinetics are bi-exponential with lifetimes around 0.5 ns and 2.5 ns and an increasing contribution of the short-lived component with an increasing amount of lignin. Both data sets indicate that a quantification of residual lignin in cellulose samples obtained after decomposition of beech wood appears possible in a concentration range of 2–10 %. This may provide a non-destructive and label-free test of the quality of decomposition.
‘Schmidbaur gold chemistry’ and beyond
Authors: Bezuidenhout Daniela I. , Esterhuysen Catharine , Dobrzańska Liliana , Cronje Stephanie , Raubenheimer Helgard G. 
Published: January 2025

Abstract
Hubert Schmidbaur has significantly influenced the field of gold chemistry. His work on preparing various aurocyclic digold compounds and studying their structures and reactivities has laid the foundation for unique applications in photophysics and homogeneous catalysis. The naming and characterization, both experimental and theoretical, of the aurophilicity phenomenon have led to numerous interdisciplinary applications. The emergence and development of dynamic gold chemistry in the excited state, exemplify this impact. Preparative methodologies, characterization techniques, and qualitative bonding theories have been tested through the rational preparation of ligated, element-centred gold clusters. The potential of this fascinating class of compounds remains largely untapped.