bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cytomorphological spectrum of pilomatricoma – A series of 28 cases
Authors: Ahuja Sana , Zaheer Sufian 
Published: February 2023

AbstractBackgroundPilomatricoma is a benign tumour that originates in the outer sheath of the hair follicle root. The clinical diagnosis of this rare entity is often missed, possibly due to a lack of awareness. Its characteristic cytomorphological features are sheets of ghost cells, basaloid cells, calcification and foreign body giant cell reaction. However, the above features may not all be present in all cases, rendering cytological diagnosis difficult.Materials and MethodsThis retrospective study included all cases of pilomatricoma diagnosed on fine needle aspiration over a period of 4 years. The histopathological diagnosis was retrieved for the cases wherever possible. A detailed histopathological and cytological evaluation was performed for the various components—basaloid cells, ghost cells, calcified debris, foreign body giant cells, bare nuclei, neutrophils, and macrophages—and they were graded on a scale of 0 to 3+.ResultsThe 28 cases included 8 female and 20 male patients with a mean age of 34.6 years. Most cases (22 cases; 78.6%) were located in the head and neck, with the scalp being the most common site. Twenty‐five cases were cytologically diagnosed as pilomatricoma based on a variable admixture of the various components—nests of basaloid cells, ghost cells, foreign body giant cell reaction, calcified debris and viable squamous cells.However, in two cases which showed an absence of basaloid cells, a differential diagnosis of epidermal inclusion cyst was also included. Another case showed a predominance of basaloid cells with a paucity of ghost cells, so a differential diagnosis of adnexal tumour was also included. Among all the cytological parameters, sheets of ghost cells followed by nests of basaloid cells and foreign body giant cell reaction had the highest sensitivity in the cytological diagnosis of pilomatricoma.ConclusionThe presence of sheets of ghost cells is the most sensitive parameter for the cytological diagnosis of pilomatricoma. It is important that pilomatricoma should be considered in the differential diagnosis of subcutaneous masses, particularly in the head and neck region.
Machine learning for non‐invasive sensing of hypoglycaemia while driving in people with diabetes
Authors: Lehmann Vera , Zueger Thomas , Maritsch Martin , Kraus Mathias , Albrecht Caroline , Bérubé Caterina , Feuerriegel Stefan , Wortmann Felix , Kowatsch Tobias , Styger Naïma , Lagger Sophie , Laimer Markus , Fleisch Elgar , Stettler Christoph 
Published: February 2023

AbstractAimTo develop and evaluate the concept of a non‐invasive machine learning (ML) approach for detecting hypoglycaemia based exclusively on combined driving (CAN) and eye tracking (ET) data.Materials and MethodsWe first developed and tested our ML approach in pronounced hypoglycaemia, and then we applied it to mild hypoglycaemia to evaluate its early warning potential. For this, we conducted two consecutive, interventional studies in individuals with type 1 diabetes. In study 1 (n = 18), we collected CAN and ET data in a driving simulator during euglycaemia and pronounced hypoglycaemia (blood glucose [BG] 2.0‐2.5 mmol L−1). In study 2 (n = 9), we collected CAN and ET data in the same simulator but in euglycaemia and mild hypoglycaemia (BG 3.0‐3.5 mmol L−1).ResultsHere, we show that our ML approach detects pronounced and mild hypoglycaemia with high accuracy (area under the receiver operating characteristics curve 0.88 ± 0.10 and 0.83 ± 0.11, respectively).ConclusionsOur findings suggest that an ML approach based on CAN and ET data, exclusively, enables detection of hypoglycaemia while driving. This provides a promising concept for alternative and non‐invasive detection of hypoglycaemia.
Predicting the age at maturity of Asian carp using air temperature
Authors: Brook Madison E. , Cuddington Kim , Koops Marten A. 
Published: February 2023

AbstractAsian carp (bighead carp, Hypophthalmichthys nobilis; grass carp, Ctenopharyngodon idella and silver carp, H. molitrix) are a group of invasive species that are predicted to cause ecological effects if they invade the Great Lakes basin. Although Asian carp age at maturity is known to be an important factor in the risk of establishing a population, there is relatively little maturity data for North America. We found that air temperature can be used to predict the age at maturity of Asian carp. Nonlinear regressions using mean annual air temperature and annual degree days to predict age at maturity explain 60% and 62% of the variation respectively. These models predict that maturation is possible in locations that were previously excluded from Asian carp spawning range based on data from the Amur River. As expected, we find faster maturation in more southern areas of North America, although there are relatively large errors predicting age at maturity in the Mississippi River population. We conclude that due to the effect of faster maturation on population growth rates, southern Great Lakes locations (e.g. Lake Erie) may be at greater risk of faster population establishment.
Cortactin expression in a Norwegian cohort of human papilloma virus negative oral squamous cell carcinomas of the mobile tongue
Authors: Sengüven Toközlü B. , Sapkota D. , Vallenari E. M. , Schreurs O. , Søland T. M. 
Published: February 2023

AbstractOral squamous cell carcinoma of the tongue (OTSCC) is the most common malignancy among oral squamous cell carcinomas and is frequently associated with an unfavorable prognosis. Local spread and distant metastasis are important causes of poor prognosis in OTSCC. Cortactin amplification and overexpression, a common molecular alteration in oral squamous cell carcinomas, have been linked to invasion and metastasis of tumor cells. However, the intra‐tumor expression pattern and prognostic significance of cortactin in human papillomavirus (HPV) negative OTSCC is not fully investigated. Immunohistochemical analysis using tissue microarray consisting of formalin‐fixed and paraffin‐embedded HPV negative OTSCC (n = 123) specimens showed overexpression of cortactin at tissue cores from invading fronts as compared to the corresponding center cores. High overall cortactin expression was found to be associated with advanced (larger) tumor size and the occurrence of distance metastasis. Kaplan‐Meier survival analysis showed that patients with high overall cortactin expression were associated with reduced 5‐year survival. Multivariate Cox regression analysis identified high cortactin expression to be an independent prognostic factor in OTSCC. Additionally, siRNA‐mediated silencing of cortactin was found to suppress the proliferative and invasive abilities of OTSCC cells in an organotypic co‐culture model. Overexpression of cortactin is a promising prognostic marker in HPV‐negative OTSCC.
COMPETITIVE MARKET BEHAVIOR: CONVERGENCE AND ASYMMETRY IN THE EXPERIMENTAL DOUBLE AUCTION
Authors: Ikica Barbara , Jantschgi Simon , Nax Heinrich H. , Duran Diego G. Nuñez , Pradelski Bary S. R. 
Published: February 2023

AbstractWe conducted a large number of controlled continuous double auction experiments to reproduce and stress‐test the phenomenon of convergence to competitive equilibrium under private information with decentralized trading feedback. Our main finding is that across a total of 104 markets (involving over 1,700 subjects), convergence occurs after a handful of trading periods. Initially, however, there is an inherent asymmetry that favors buyers, typically resulting in prices below equilibrium levels. Analysis of over 80,000 observations of individual bids and asks helps identify empirical ingredients contributing to the observed phenomena including higher levels of aggressiveness initially among buyers than sellers.
A review of current treatments for chronic prostatitis/chronic pelvic pain syndrome under the UPOINTS system
Authors: Maeda Koki , Shigemura Katsumi , Fujisawa Masato 
Published: February 2023

AbstractProstatitis is classified into four categories according to the National Institutes of Health Consensus Classification. The largest category, Category III chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS), has a wide range of symptoms and is difficult to diagnose because diagnosis is based on exclusion. Although many treatment modalities, including both pharmacological and non‐pharmacological treatments, have been tried, definitive treatment methods have not yet been established, and many urologists struggle with the daily treatment of these conditions. The reasons for the failure of treatment are not only the wide variety of symptoms, but also the wide variety of causes. Therefore, the UPOINTS system is widely used, in which treatment methods are divided or combined according to symptoms and causes. This article summarizes the reports on treatment and reviews treatment findings for CP/CPPS in accordance with the UPOINTS system.
Genetic population structure of Pseudoplatystoma corruscans (Siluriformes: Pimelodidae) and evidence of temporal variation in structure
Authors: Rueda Eva C. , Machado Carolina B. , Castro Veronica , Braga‐Silva Alline , Ojeda Guillermo , Vargas Facundo , Loretán Gisela , Freitas Patricia D. , Galetti Pedro M. , Ortí Guillermo 
Published: February 2023

AbstractSurubim (Pseudoplatystoma corruscans, Pimelodidae) are migratory catfish native to the rivers in the La Plata and São Francisco basins. They are piscivores that attain considerable body sizes and are a valuable economic resource. Surubim exhibits extensive migrations during its life cycle that may affect the population structure at vast geographic scales. The authors examined the genetic diversity and population genetic structure of P. corruscans using microsatellite markers from a comprehensive sampling of 260 individuals from the Upper and Lower Paraná River. They identified two well‐differentiated genetic clusters corresponding to a natural geographic barrier historically separating Upper and Lower Paraná regions. They also demonstrated temporal variation in population genetic structure at a site in Lower Paraná close to the confluence with the Paraguay River, most likely explained by the influx of migrant fishes at certain times of the year.
Association between types of home healthcare and emergency house calls, hospitalization, and end‐of‐life care in Japan
Authors: Sun Yu , Iwagami Masao , Komiyama Jun , Sugiyama Takehiro , Inokuchi Ryota , Sakata Nobuo , Ito Tomoko , Yoshie Satoru , Matsui Hiroki , Kume Keitaro , Sanuki Masaru , Kato Genta , Mori Yukiko , Ueshima Hiroaki , Tamiya Nanako 
Published: February 2023

AbstractBackgroundTo meet the increasing demand for home healthcare in Japan, as part of the national healthcare system, home care support clinics/hospitals (HCSCs) and enhanced HCSCs were introduced in 2006 and 2012 respectively. This study aimed to evaluate whether HCSCs has succeeded in providing 24‐h home care services through the end of life.MethodsA retrospective cohort study was conducted using the national database in Japan. Participants were ≥ 65 years of age, had newly started regular home visits between July 2014 and September 2015, and used general clinics, conventional HCSCs, or enhanced HCSCs. Each patient was followed up for 6 months after the first visit. The outcome measures were (i) emergency house call(s), (ii) hospitalization(s), and (iii) end‐of‐life care defined as in‐home death. Multivariable logistic regression analyses were performed for statistical analysis.ResultsThe analysis included 160,674 patients, including 13,477, 64,616, and 82,581 patients receiving regular home visits by general clinics, conventional HCSCs, and enhanced HCSCs respectively. Compared to general clinics, the use of conventional and enhanced HCSCs was associated with an increased likelihood of emergency house calls (adjusted odds ratio [aOR] and 95% confidence intervals [CIs] of 1.62 [1.56–1.69] and 1.86 [1.79–1.93], respectively) and a decreased likelihood of hospitalizations (aOR [95% CIs] of 0.86 [0.82–0.90] and 0.88 [0.84–0.92] respectively). Among 39,082 patients who died during the follow‐up period, conventional and enhanced HCSCs had more in‐home deaths (aOR [95% CIs] of 1.46 [1.33–1.59] and 1.60 [1.46–1.74], respectively) compared to general clinics.ConclusionsHCSCs (especially enhanced HCSCs) provided more emergency house calls, reduced hospitalization, and enabled expected deaths at home, suggesting that further promotion of HCSCs (especially enhanced HSCSs) would be advantageous.
Credit Market Frictions and Coessentiality of Money and Credit
Authors: KWON OHIK , LEE MANJONG 
Published: February 2023

AbstractWe explore how credit market frictions matter for the coessentiality of money and credit. Limited commitment calls for credit limits that are tailored according to borrowers' productivity. Under an adverse selection problem caused by asymmetric information, however, lenders impose the credit limit of the low‐productivity borrower onto the high‐productivity borrower. If productivities differ sufficiently between borrowers, the high‐productivity borrower is credit‐constrained and is willing to hold money to compensate for the deficiency of their credit limit, whereas the low‐productivity borrower is not. This implies the coessentiality of money and credit in the sense that their simultaneous use improves welfare.
Examining Enhanced Implementation of Routine Antenatal Care Practices to Support Healthy Pregnancy Weight Gain
Authors: Hoch Mikeeley , Meloncelli Nina , de Jersey Susan 
Published: February 2023

IntroductionCurrent antenatal guidelines advocate for regular weighing of women during their pregnancy, with supportive conversations to assist healthy gestational weight gain (GWG). To facilitate overcoming weight monitoring barriers, a pregnancy weight gain chart (PWGC), coupled with brief intervention advice, was implemented in 2016 to guide provider and woman‐led routine weight monitoring. This study aimed to examine the extent to which the use of PWGCs and routine advice provision were normalized into routine antenatal care following enhanced implementation strategies and whether this led to a change in GWG.MethodsThis pre‐post study included data from 2010 (preimplementation), 2016, and 2019 (postimplementation). A retrospective audit of health records and PWGCs was undertaken to assess adherence to chart use and evaluate GWG outcomes. A survey was sent to women in 2010 and repeated in 2019 to understand the advice women received from health care professionals.ResultsCompared with the preimplementation cohort (2010), more women achieved a healthy GWG in 2019 (42% vs 31%,P= .04). In 2019, having 3 or more weights recorded was associated with a reduction in excess GWG (P= .028). More women reported receiving helpful advice about healthy GWG in 2019 compared with 2010, although minimal changes to advice received about nutrition and physical activity were observed.DiscussionEnhanced implementation strategies and ongoing efforts to optimize supportive antenatal care practices are required to effect positive change in GWG. Further evaluation of the perspectives of pregnant women and counseling practices of health professionals is needed.
Prisoners' experience of health self‐management: A qualitative study
Authors: Avieli Hila 
Published: February 2023

AbstractPurposeAmong the noninstitutionalized population, health care is increasingly shifting from a paternalistic model toward promoting patients' involvement in decision‐making and in managing their condition. This paradigm shift toward health self‐management is less applicable to individuals in prison whose health management choices are limited. The aim of this study was to explore prisoners' health self‐management needs and the strategies used to maintain health self‐management in a highly restrictive prison environment.DesignA qualitative phenomenological study design was selected for this research.MethodsAn interpretive phenomenological analysis was chosen to present the narratives of prisoners regarding their health self‐management. Semi‐structured interviews were conducted with 15 male prisoners followed by content analysis.ResultsThe analysis of the participants' narratives revealed four major themes: (1) “I thrive on the anger so I can turn it into some more sit‐ups:” Initiating sporting activities (2) “Food shouldn't be that white…:” Prisoners' quest for healthier eating (3) “I felt I want more out of life…:” Avoiding an unhealthy lifestyle (4) “I want to be taken care of:” The struggle for better health care.ConclusionsThe findings suggest that prisoners can overcome the challenges of maintaining health in prison and become committed to better health management. Prisoners who serve as health resources may help reduce the load on correctional facilities' health care systems and the public.
Beyond the genomes of Fulvia fulva (syn. Cladosporium fulvum) and Dothistroma septosporum: New insights into how these fungal pathogens interact with their host plants
Authors: Mesarich Carl H. , Barnes Irene , Bradley Ellie L. , de la Rosa Silvia , de Wit Pierre J. G. M. , Guo Yanan , Griffiths Scott A. , Hamelin Richard C. , Joosten Matthieu H. A. J. , Lu Mengmeng , McCarthy Hannah M. , Schol Christiaan R. , Stergiopoulos Ioannis , Tarallo Mariana , Zaccaron Alex Z. , Bradshaw Rosie E. 
Published: February 2023

AbstractFulvia fulva and Dothistroma septosporum are closely related apoplastic pathogens with similar lifestyles but different hosts: F. fulva is a pathogen of tomato, whilst D. septosporum is a pathogen of pine trees. In 2012, the first genome sequences of these pathogens were published, with F. fulva and D. septosporum having highly fragmented and near‐complete assemblies, respectively. Since then, significant advances have been made in unravelling their genome architectures. For instance, the genome of F. fulva has now been assembled into 14 chromosomes, 13 of which have synteny with the 14 chromosomes of D. septosporum, suggesting these pathogens are even more closely related than originally thought. Considerable advances have also been made in the identification and functional characterization of virulence factors (e.g., effector proteins and secondary metabolites) from these pathogens, thereby providing new insights into how they promote host colonization or activate plant defence responses. For example, it has now been established that effector proteins from both F. fulva and D. septosporum interact with cell‐surface immune receptors and co‐receptors to activate the plant immune system. Progress has also been made in understanding how F. fulva and D. septosporum have evolved with their host plants, whilst intensive research into pandemics of Dothistroma needle blight in the Northern Hemisphere has shed light on the origins, migration, and genetic diversity of the global D. septosporum population. In this review, we specifically summarize advances made in our understanding of the F. fulva–tomato and D. septosporum–pine pathosystems over the last 10 years.
A city in a bunker in a city: Demilitarizing art in South Korea
Authors: Gitzen Timothy 
Published: February 2023

AbstractLocated mere feet from the busy Yeouido Bus Transfer Center, the Seoul Museum of Art (SeMA) Bunker is a former military bunker from 1970s authoritarian South Korea that now showcases changing art exhibits. Debuting in November 2019,Paju(by artist Kim Seung Rea) features a series of paintings and statues capturing life in the town of Paju in the Geyeonggi Province near the border of the Demilitarized Zone (DMZ) that separates North and South Korea. As a critique of militarization,Pajunot only offers a glimpse into the life that blossoms amidst the guard towers, bulwarks, and barbed wire, it challenges the power dynamic implicit in the space of the bunker. Cold War ideologies overlap in SeMA Bunker, for while the bunker was purportedly designed to keep the former president, Park Chung‐hee, safe during potential North Korean attack, the town of Paju was to act as human and infrastructural sacrifice to keep the rest of the country secure. Therefore, to bring Paju into the bunker via the exhibit is to inverse that power relationship and thus work to demilitarize the space, the town, and ultimately the patrons.
N‐hydroxypipecolic acid induces systemic acquired resistance and transcriptional reprogramming via TGA transcription factors
Authors: Yildiz Ipek , Gross Marlene , Moser Denise , Petzsch Patrick , Köhrer Karl , Zeier Jürgen 
Published: February 2023

AbstractN‐hydroxypipecolic acid (NHP) accumulates in pathogen‐inoculated and distant leaves of the Arabidopsis shoot and induces systemic acquired resistance (SAR) in dependence of the salicylic acid (SA) receptor NPR1. We report here that SAR triggered by exogenous NHP treatment requires the function of the transcription factors TGA2/5/6 in addition to NPR1, and is further positively affected by TGA1/4. Consistently, a tga2/5/6 triple knockout mutant is fully impaired in NHP‐induced SAR gene expression, while a tga1/4 double mutant shows an attenuated, partial transcriptional response to NHP. Moreover, tga2/5/6 and tga1/4 exhibited fully and strongly impaired pathogen‐triggered SAR, respectively, while SA‐induced resistance was more moderately compromised in both lines. At the same time, tga2/5/6 was not and tga1/4 only partially impaired in the accumulation of NHP and SA at sites of bacterial attack. Strikingly, SAR gene expression in the systemic tissue induced by local bacterial inoculation or locally applied NHP fully required functional TGA2/5/6 and largely depended on TGA1/4 factors. The systemic accumulation of NHP and SA was attenuated but not abolished in the SAR‐compromised and transcriptionally blocked tga mutants, suggesting their transport from inoculated to systemic tissue. Our results indicate the existence of a critical TGA‐ and NPR1‐dependent transcriptional module that mediates the induction of SAR and systemic defence gene expression by NHP.
When others control risks: Others‐focused coping with risks from energy projects
Authors: Vrieling Leonie , Perlaviciute Goda , Steg Linda 
Published: February 2023

AbstractEnergy projects can cause various risks over which people have little control, because they are usually developed, implemented, and managed by external parties, such as governments and industry. This study aims to examine how people cope with such externally controlled risks from energy projects, in particular earthquakes induced by gas extraction in their region. Specifically, we studied which factors influence people's intentions to engage in emotion‐focused coping aimed at reducing negative emotions, and problem‐focused coping aimed at reducing the risks and/or their negative consequences. Extending previous studies, we distinguish two types of problem‐focused coping that may be relevant when facing externally controlled risks, namely self‐focused coping, in which individual themselves take action to reduce the negative consequences of the risks, and others‐focused coping, in which case individuals urge responsible parties to take actions to reduce the risks. Our results show that the three types of coping can be distinguished empirically, and people are likely to engage in others‐focused coping. Further, people are most likely to engage in others‐focused coping when they experience strong morality‐based emotions toward the risks from energy projects, whereas they are most likely to engage in self‐focused coping and emotion‐focused coping when they experience strong negative consequence‐based emotions toward the risks from energy projects.