bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hypertension as a Novel Link for Shared Heritability in Age at Menarche and Cardiometabolic Traits
Authors: Fan Hsien-Yu , Chien Kuo-Liong , Huang Yen-Tsung , Hsu Justin BoKai , Chen Yun-Yu , Lai En-Yu , Su Jia-Ying , Lu Tzu-Pin , Li Hung-Yuan , Hsu Shih-Yuan , Chen Yang-Ching 
Published: February 2023

Abstract

Context
Extremely early age at menarche, also called precocious puberty, has been associated with various cardiometabolic traits, but their shared heritability remains unclear.

Objectives
This work aimed to identify new shared genetic variants and their pathways for age at menarche and cardiometabolic traits and to investigate the influence of central precocious puberty on childhood cardiometabolic traits.

Methods
Using the conjunction false discovery rate method, this study analyzed genome-wide association study data from the menarche-cardiometabolic traits among 59 655 females of Taiwanese ancestry and systemically investigated pleiotropy between age at menarche and cardiometabolic traits. To support the novel hypertension link, we used the Taiwan Puberty Longitudinal Study (TPLS) to investigate the influence of precocious puberty on childhood cardiometabolic traits.

Results
We discovered 27 novel loci, with an overlap between age at menarche and cardiometabolic traits, including body fat and blood pressure. Among the novel genes discovered, SEC16B, CSK, CYP1A1, FTO, and USB1 are within a protein interaction network with known cardiometabolic genes, including traits for obesity and hypertension. These loci were confirmed through demonstration of significant changes in the methylation or expression levels of neighboring genes. Moreover, the TPLS provided evidence regarding a 2-fold higher risk of early-onset hypertension that occurred in girls with central precocious puberty.

Conclusion
Our study highlights the usefulness of cross-trait analyses for identifying shared etiology between age at menarche and cardiometabolic traits, especially early-onset hypertension. The menarche-related loci may contribute to early-onset hypertension through endocrinological pathways.
Becoming Laborers
Authors: Zhu Ping 
Published: February 2023

AbstractThis article shows that the construction of the notion of dignified laborer during the Chinese New Culture Movement (1915–24) was not simply a reversal of preexisting social hierarchy that placed the mental laborers above the manual laborers but rather a complex and profound process of identity formation that created dynamic equalization between the national and the global, mental laborers and manual laborers, as well as men and women. Through reading a series of cultural and literary works, this article shows that the dignified laborer was an inclusive modern identity that gained traction during the New Culture Movement, when the Chinese intellectuals sought ways to foster national solidarity, realize the full potential of humanity, facilitate intersubjective understanding, and mend social divisions. As a result, this was a period when Chinese people from all walks vied to become laborers with dignity, amidst a rising democratic culture of reciprocal equal recognition.
Technical Requirements for Clinical Exercise Physiologists as Qualified Health Professionals
Authors: Overstreet Brittany , Ward-Ritacco Christie , Neric Francis , Brawner Clinton A. , Thompson Benjamin , Hargens Trent , Thompson Walt 
Published: February 2023

Apply It!
• Readers will be able to advocate for the field of clinical exercise physiology with an enhanced understanding of the current state of the profession.
• Readers will have a platform to have discussions with other allied health professionals to increase awareness of the role of a clinical exercise physiologist in a health care setting.
Promoting Physical Activity in Rural Communities During COVID-19 with Exercise is Medicine® on Campus
Authors: Wedig Isaac J. , Phillips Jamie J. , Kamm Kelly B. , Elmer Steven J. 
Published: February 2023

Apply It!
By reading this article, the health and fitness professional will:
• Recognize the urgency for widespread promotion and implementation of physical activity during the COVID-19 pandemic
• Learn how Exercise is Medicine On Campus (EIM-OC) can be used to promote physical activity in the surrounding communities, especially those in rural areas
• Explore strategies for promoting, adapting, and facilitating physical activity during the pandemic and beyond
• Consider collaborating with an EIM-OC program to improve community health
The underexamined role of money and how it undermines Nozick’s case for right libertarianism
Authors: Grela Helen 
Published: February 2023

In Anarchy, State and Utopia, Nozick presented his doctrine of right libertarianism, largely a contemporary restatement of Locke’s moral imperative that an individual’s rights to his life, liberty, and property are absolute and place limits on state action. Parallelly, Nozick espoused the free-market system as a framework that not only respects individual rights but ensures material benefits. While the free market results in radical inequalities in holdings and widespread dispossession, Nozick treats the process as morally just and any state redistribution through taxation as wrong. However, neither Nozick nor his many critics fully considered the role of money in capitalist free markets, an omission I begin to address.

Nozick asserts that money emerges pre-politically through the uncoerced actions of individuals, and that it derives its value from the commodity that underpins it. This conception of money underpins Nozick’s claims that a minimal state can be just and that the free-market system is a moral, efficient, and neutral allocator of resources. However, Nozick’s approach omits addressing how money’s general acceptability and stability are achieved. Answers can be found in heterodox economic paradigms, which put the state at the center of money creation, rendering money (and the state) incompatible with natural rights. Furthermore, by insisting on money’s commodity nature, Nozick ignores the seventeenth century revolution in money, necessitated by the emergence of free-market capitalism and commodity money’s inability to underpin it. In other words, it is not commodity money but credit money that should be the proper object of Nozick’s analysis. I go on to analyze what credit money is, how it arose, and why some form of it is necessary in a free-market context. Ultimately, I argue that it is not compatible with natural rights and is itself redistributive.
Key words: money, distributive justice, Nozick, Locke, free market capitalism, natural rights
The Composite Overfit Analysis Framework: Assessing the Out-of-Sample Generalizability of Construct-Based Models Using Predictive Deviance, Deviance Trees, and Unstable Paths
Authors: Danks Nicholas P. , Ray Soumya , Shmueli Galit 
Published: February 2023

Construct-based models have become a mainstay of management and information systems research. However, these models are likely overfit to the data samples upon which they are estimated, making them risky to use in explanatory, prescriptive, or predictive ways outside a given sample. Empirical researchers currently lack tools to analyze why and how their models may not generalize out of sample. We propose a composite overfit analysis (COA) framework that applies predictive tools to describe the sources and ramifications of overfit in terms of the focal concepts important to empirical researchers: cases, constructs, and causal paths. The COA framework begins by using a leave-one-out crossvalidation procedure to identify cases with unusually high predictive error given their in-sample fit—a difference we describe as predictive deviance. The framework then employs a novel deviance tree method to group deviant cases that have similar predictive deviance and for similar theoretical reasons. We then employ a leave-deviant-group-out method, which sequentially analyzes how each deviant group affects model parameters, thereby identifying potentially unstable paths in the model. We can then infer descriptive reasons for why and how overfit affects a given model and data sample using the grouping criteria of the deviance tree, construct scores of deviant groups, and resulting unstable paths. These insights allow researchers to identify unexpected behavior that could define boundary conditions of their theory or point to new theoretical phenomena. We demonstrate the practical utility of our analytical framework on a technology adoption model in a new context. This paper was accepted by Dongjun Wu, information systems. Funding: This work was partially supported by the Ministry of Science and Technology, Taiwan [Grants 109-2811-H-007-503 and 108-2410-H-007-091-MY3] and by the 2021 Arts and Social Sciences Benefaction Fund of Trinity College Dublin, Ireland. Supplemental Material: The data files and online appendix are available at https://doi.org/10.1287/mnsc.2023.4705 .
Detecting Human Trafficking: Automated Classification of Online Customer Reviews of Massage Businesses
Authors: Li Ruoting , Tobey Margaret , Mayorga Maria E. , Caltagirone Sherrie , Özaltın Osman Y. 
Published: February 2023

Problem definition: Approximately 11,000 alleged illicit massage businesses (IMBs) exist across the United States hidden in plain sight among legitimate businesses. These illicit businesses frequently exploit workers, many of whom are victims of human trafficking, forced or coerced to provide commercial sex. Academic/practical relevance: Although IMB review boards like Rubmaps.ch can provide first-hand information to identify IMBs, these sites are likely to be closed by law enforcement. Open websites like Yelp.com provide more accessible and detailed information about a larger set of massage businesses. Reviews from these sites can be screened for risk factors of trafficking. Methodology: We develop a natural language processing approach to detect online customer reviews that indicate a massage business is likely engaged in human trafficking. We label data sets of Yelp reviews using knowledge of known IMBs. We develop a lexicon of key words/phrases related to human trafficking and commercial sex acts. We then build two classification models based on this lexicon. We also train two classification models using embeddings from the bidirectional encoder representations from transformers (BERT) model and the Doc2Vec model. Results: We evaluate the performance of these classification models and various ensemble models. The lexicon-based models achieve high precision, whereas the embedding-based models have relatively high recall. The ensemble models provide a compromise and achieve the best performance on the out-of-sample test. Our results verify the usefulness of ensemble methods for building robust models to detect risk factors of human trafficking in reviews on open websites like Yelp. Managerial implications: The proposed models can save countless hours in IMB investigations by automatically sorting through large quantities of data to flag potential illicit activity, eliminating the need for manual screening of these reviews by law enforcement and other stakeholders. Funding: This work was supported by the National Science Foundation [Grant 1936331]. Supplemental Material: The online appendix is available at https://doi.org/10.1287/msom.2023.1196 .
When Does External Knowledge Benefit Team Creativity? The Role of Internal Team Network Structure and Task Complexity
Authors: Venkataramani Vijaya , Tang Chaoying 
Published: February 2023

Creativity in teams is spurred by members’ access to diverse knowledge, often from interactions with external sources. However, not all teams that have the capabilities to acquire such external knowledge are equally creative. Integrating theories of absorptive capacity and creative synthesis in teams, we propose that teams’ external knowledge acquisition capabilities in securing a wide variety of knowledge resources need to be complemented by internal knowledge integration capabilities that facilitate balanced/equal participation of all team members in the creative problem-solving process. In turn, this combination enables effective information elaboration processes underlying the generation of truly creative team outcomes. We test these ideas in two field studies. First, in a sample of 81 research and development teams in three organizations in science and technology fields, we find that teams’ connections with a wide range of external parties—indicating their external knowledge acquisition capability—benefit their creativity, but only when the team’s internal team member problem-solving network structure—an indicator of the team’s knowledge integration capability—is less centralized (i.e., not controlled by one or few members). We further demonstrate that these effects are more salient when the team’s task is more complex. Replicating these findings in a second sample of 57 project teams in an energy manufacturing and services firm, we show that these effects are mediated by the team’s information elaboration processes. Theoretical and practical implications are discussed. Funding: This research was supported by grants received by C. Tang and her colleagues at UCAS, from the National Natural Science Foundation of China [Projects 71974178, 71932009], MOE Social Science Laboratory of Digital Economic Forecasts and Policy Simulation at UCAS, and the Fundamental Research Funds for the Central Universities [Project E2E40806X2]. Supplemental Material: The online appendix is available at https://doi.org/10.1287/orsc.2023.1661 .
Self-mutilation in people with psychiatric diagnosis - literature review
Authors: Drzał Ewelina , Banaszek Agnieszka , Stanicki Paweł , Wingralek Zuzanna 
Published: February 2023

Introduction: Self-mutilation is of an auto-aggressive nature. They take many forms. Usually they do not occur as an isolated phenomenon. Self-injuring persons often have a diagnosed mental disorder, and a psychiatric diagnosis is one of the risk factors for the occurrence of self-harm.
Material and method: In this study, articles were analyzed that contained information on the occurrence of various mental disorders. These articles searched for information on the occurrence of self-mutilation, its type, origin and causes.
Discussion: Self-mutilation is common in patients with a psychiatric diagnosis. The frequency of such behaviors can range from 33% to 50% in people with autism, up to 22%, and even 49% in people diagnosed with psychotic disorders. Acts of selfharm may affect 50-78% of people diagnosed with border-line personality disorder. In adolescents with eating disorders, 41% of patients report self-harm. In the group of people diagnosed with bipolar disorder, it may be as high as 77.3%. People with depression are also a large self-injuring group. It is reported that it may be up to 71.2% of patients with unipolar disorder.
Conclusions: Self-mutilation is a phenomenon that is more and more topical and common not only in the adolescent population. This is a multi-factorial issue. One of the risk factors are mental disorders. Self-mutineers choose various methods, and this choice depends, among others, on from recognition. The size of the phenomenon and its evolution make it necessary to study it in order to increase the level of knowledge, update information and, consequently, the ability to help people at risk of NSSI.

Keywords: self-mutilation, autism spectrum disorder, schizophrenia, bipolar disorder, personality disorders
Validación de un instrumento para medir el respeto de la autonomía del paciente en situación terminal durante la toma de decisiones médicas sobre el final de la vida
Authors: González-Huerta José Isaac , Medina-Ceja Laura , Espinel-Bermudez Maria Claudia , Alvarez-Del Rio Asuncion , Medina-Arellano Maria de Jesus , Cordova-Jimenez Irene 
Published: February 2023

Antecedentes: El respeto por la autonomía de la persona consiste en considerarlas preferencias y valores de la persona enferma durante la toma de decisions sobre el tipo de atención que recibe y es un elemento bioético-jurídico. Sin embargo, no existen instrumentos validados sobre este fenómeno que ayuden aclarificar la percepción del médico sobre este principio. Objetivo: Elaborar, validar mediante juicio de expertos y pilotear para obtener la consistencia interna de un instrumento que evalúa el nivel de acuerdo de los médicos sobre los diferentes elementos que constituyen el respeto por la autonomía de la persona enferma en etapa terminal. Métodos: Estudio transversal. Método de validación por juicio de diez expertos de México. El instrumento se piloteó en médicos de un hospital público de alta especialidad para determinar la consistencia interna del mismo. Resultados: Se generó un instrumento de 15 ítems con un índice de validez de contenido de 0.82 para 10 expertos. Fue piloteado en una muestra de 96 médicos. Se obtuvo un alfa de Cronbach de 0.694. Conclusiones: Se desarrolló, validó y evaluó la consistencia interna de un cuestionario para medir el nivel de acuerdo de médicos que atienden a persones enfermas en etapa terminal con relación a los aspectos constitutivos sobre el respeto de su autonomía. Se recomienda su aplicación en médicos para corroborar su utilidad y favorecer un diagnóstico situacional sobre la situación estudiada.
Optical Data Storage Technology for Consumer Electronics
Authors: Huijser A. , Carasso M.G. 
Published: February 2023

Consumer products based on new technologies are often introduced after a succesfull application of that technology in professional equipment.
Optical recording is an exception to this rule. Consumer applications of this technique as in the Laser-Vision video-disc and the Compact Disc digital audio systems are already for sale which cannot be said for the professional digital optical recorder (DOR) systems. This situation is partial due to different fields of interest, i.e. read-only (ROM) applications for the present consumer market and direct-read-after-write (DRAW) systems for professional use: a difference in media rather than in optical principles.
A Proposal for the Integration of Digital Optical Storage into the Mass Storage System (MSS) at the National Center for Atmospheric Research (NCAR)
Authors: Choy Joseph H. , O'Lear Bernard T. 
Published: February 2023

NCAR is currently operating an AMPEX Terabit Memory (TBM)* system. This system was purchased for 1.1 million dollars, installed in March of 1976, and placed into full operation by February 1977. During the subsequent years, over two million dollars has been spent in system upgrades. The final $300,000 upgrade is currently underway. The system is currently managing approximately 9 × 1012 bits. The application for optical disk data storage that NCAR would be interested in pursuing at this time would be phased over the following sequence of events:
• Installation of an initial optical disk product connected to a CRAY-1A computer and the subsequent procurement of additional hardware capability for the purpose of building a new MSS capability.
• Designate the TBM as a READ ONLY device within the NCAR local network and commence the offload procedure, whereby all good data existing on the TBM is copied onto the optical disk MSS (ODMSS). This activity would be in addition to the normal operation of the ODMSS.
• Continually provide for system upgrades through the late 1980s and early 1990s to develop an MSS node on the local network. This node will provide data management and data storage capabilities for planned future computing enhancements which are projected to be 10 to 50 times the capability of the current CRAY-1A.
Design, Fabrication, and Testing of an f/0.3 Achromatic Focusing System
Authors: Sigler R. D. 
Published: February 2023

One of the crucial problems in laser fusion research is the efficient delivery of enormous amounts of power (typically several terawatts) to irradiate pellets of approximately 100 micrometer diameter. An illumination system consisting of a pair of ellipsoidal mirrors and aspheric single element lenses has been used with a two beam laser for several years at KMSF and has been very successful.
1. The lens surfaces are so steep that it is very difficult to apply anti-reflective coatings.
2. The lens must be very thick to accomodate short radii of curvature. The deleterious effects of high power beams propagating through refractive media are well known.
3. The lens also causes the system to be stigmatic for only one wavelength. The last item is especially important as recent experience has indicated that pellet energy absorption is increased by harmonically generated short wavelength and/or broadband laser light.
Making a Wright-Cassegrain Universal Telescope for Halley’s Comet.
Authors: De Vany Arthur S. 
Published: February 2023

The Wright-Cassegrain universal telescope system is of 12.5 inch aperture with an f/9.0 ratio and is a catadioptric, which can be converted in three various instruments.
(1). A f/2.7 Wright camera with a flat field of 5°
(2). A f/2.7 Wright-Newtonian with a flat field of 5°
(3). A f/9 Wright-Cassegrain telescope
These three instruments are with interchangeable 3 in. tubes with adjustable mounts with respective optical components converting the telescope to the desired configuration.
Ultraviolet Light Immobilized Lens Blocking Adhesive Performance Quantified Using Polymer Analysis Techniques
Authors: Caputo Fred , LeBlanc Glenn 
Published: February 2023

A new ultraviolet light cured material has been formulated as a temporary holding adhesive to mount or block glass lenses during the generating and polishing operations. This recently developed “blocking" material possesses unique properties in both the liquid and solid state. The product transforms from a liquid to solid through controlled exposure to low intensity ultraviolet light (20 to 30 mw/cm2 at 365 nm).
In the liquid state the product rheology has been devised to ensure that it meets the needs of the end user. Upon solidification, this single component product has been designed to remain rigid at room temperature after it has been cured, and release (deblock) without solvents. This paper will quantify these product parameters by employing sophisticated polymer testing equipment. The results of dynamic mechanical analysis (DMA), thermal analysis and other engineering property tests will substantiate the product's performance demands in the liquid, semi-liquid and solid stages.
Combination of surface characterization techniques for proper investigation of optical thin film morphology
Authors: Duparré Angela 
Published: February 2023

When investigating the surface morphology of thin films and substrates the following problems have to be taken into account:
- The microtopography as a two-dimensional roughness profile consists of various structural features the form, size, and distribution of which depend on the substrate and film material, polishing process, deposition procedure, and environmental conditions.
- Anisotropy and local variations of the roughness profile are likely to occur.
- The characterization techniques should be applicable to quite a large variety of different surface structures such as superpolished substrates, columnar film morphology, corroded surfaces with pronounced roughness etc.
- All techniques of surface roughness measurement are subject to bandwidth limitation. Hence, the information available depends on both the method applied and the particular properties of the sample.