bluuebunny/crossref_metadata_2025_split huggingface dataset:
US Congressional Voice: Resolutions on the Suppression of Kosovo’s Self-Governance and Human Rights (1986-1989)
Authors: Hadri Arbër 
Published: January 2025

The purpose of the research paper is to emphasize the pivotal role of the U.S. Congress in raising awareness about the Kosovo issue and violations of human rights during the late 1980s, with a specific emphasis on congressional resolutions and lobbying efforts that shaped U.S. foreign policy toward the region.
Scientific novelty. The paper is explores how legislative measures and the early lobbying efforts of prominent U.S. congressmen helped bring the plight of Kosovo Albanians to the international stage, shaping diplomatic responses to the conflict. By analyzing the intersection of domestic political advocacy and international diplomacy, the paper offers valuable insights into early legislative actions and their influence on global political outcomes and human rights initiatives.
Conclusions. In the late 1980s, the U.S. Congress played a pivotal role in addressing the severe human rights violations faced by the Albanian population in Kosovo under Yugoslav rule. Congressional actions, including resolutions introduced by key figures like Congressman Joseph DioGuardi and Senator Robert Dole in 1986 and 1987, condemned the systematic oppression of ethnic Albanians. These initiatives emphasized adherence to international agreements such as the Helsinki Final Act and called for the release of political prisoners. Additional resolutions from 1989, championed by Congressman Tom Lantos, William S. Broomfield, and Benjamin Gilman, further reinforced this stance by condemning Serbia’s efforts to revoke Kosovo’s autonomy and advocating for the Albanians’ right to self-determination and human rights.
This period marked a significant shift in international awareness, with the U.S. Congress acting as a critical voice in highlighting the plight of Kosovo’s ethnic Albanians. Legislative efforts laid the groundwork for integrating Kosovo’s struggles into U.S. foreign policy. Resolution 358 of 1986 was particularly impactful, bringing the issue to the forefront of U.S. diplomacy. By calling for political reforms and the restoration of self-determination in the form of a federal republic, these measures represented the first substantial foreign institutional support for Kosovo’s marginalized population.
At a time when Albanian-American lobbying was still developing, these congressional actions were instrumental in shaping future diplomatic and political pressure on Yugoslavia. The resolutions underscored U.S. commitments to international human rights standards, aligning with frameworks like the Helsinki Accords. They highlighted a strategic approach that emphasized human rights, legal justice, and Kosovo’s right to self-governance.
Революція Гідності на Запоріжжі (листопад 2013 – лютий 2014 рр.)
Authors: Turchenko Galyna , Totska Sofiia 
Published: January 2025

Метою статті є характеристика й аналіз подій Революції Гідності, що відбулися на території Запорізької області протягом листопада 2013 – лютого 2014 рр.
Наукова новизна полягає у тому, що в роботі вперше зроблено спробу комплексного дослідження подій Революції Гідності на території Запорізької області (листопад 2013 – лютий 2014 рр.). При підготовці статті використано матеріали інтерв’ювання учасників Революції Гідності, проаналізовано події Євромайдану та Антимайдану у найбільших містах Запорізької області: Запоріжжя, Пологи, Бердянськ, Мелітополь, Енергодар, Василівка.
Висновки. У ході дослідження встановлено, що події Революції Гідності охопили територію Запорізької області протягом листопада 2013 – лютого 2014 рр. Участь мешканців Запорізької області у Революції Гідності була значною. Населення Запоріжжя, Поліг, Бердянська, Мелітополя, Василівки, Енергодару активно приєднувалося до мітингів, акцій і протестів, виражаючи своє незадоволення політичною ситуацією в країні та вимагаючи демократичних змін. Численність учасників мітингів у різних містах області варіювалася від 50 осіб до 5 000 мітингарів.
На противагу Євромайдану виступав Антимайдан. Здебільшого, виступи були малочисельними й у більшості випадків відбувалися біля пам’ятників В. Леніну протягом листопада 2013 – лютого 2014 рр. Проросійськими силами висувалися ідеї та гасла «Русского мира» та «Росії – єдиної батьківщини всіх слов’янських нардів». Поширювалися заклики до Росії «стати гарантом стабільності в Україні» й «очистити місто від бандерівців».
Загалом, можна виділити 3 етапи Революції Гідності у Запорізькій області: 1 етап (листопад 2013 р.) – характеризується малочисельними виступами населення міст Запорізької області щодо підтримки асоціації з ЄС, протягом листопада 2013 р. відбувається формування протиборчих сторін проєвропейських і проросійських сил у регіоні; в соціальних мережах «Вконтакті» та «Фейсбук» населення м. Запоріжжя, Бердянську, Поліг, Василівки поширює інформацію про перші проєвропейські збори; 2 етап (грудень 2013 – січень 2014 рр.) – проходять мітинги протесту проти розгону київського Майдану; у Запоріжжі, Бердянську, Пологах, Мелітополі відбувається концентрація сил Євромайдану навколо прагнення проєвропейського майбутнього та протистояння Антимайдану; 3 етап (лютий 2014 р.) – перемога сил Євромайдану та поразка проросійськи налаштованих політичних еліт, тітушок, міліції у Запорізькій області.
Comparison of the new RIDA qLine Allergy multiparameter immunoblot and the ImmunoCAP Specific IgE test for the identification of clinically relevant food and aeroallergen allergies
Authors: Hahn Katharina K. , Schuppe Marie C. , Hollstein Moritz M. , Forkel Susann , Buhl Timo 
Published: January 2025

BackgroundMultiparameter immunoblot testing is increasingly used as an alternative to multiple individual IgE analyses for type 1 allergies. This study investigated the performance of an inexpensive immunoblot method, the RIDA qLine allergy test system (R-Biopharm AG), vs. the current gold standard.MethodsThree study-specific panels with 57 individual allergens (food and aeroallergens) were analyzed in serum samples from 200 patients with signs and symptoms of IgE-mediated allergies, using both the RIDA qLine Allergy and the reference method, the ImmunoCAP Specific IgE test (Thermo Fisher Scientific). In case of divergent results, corresponding allergens were remeasured using the secondary reference method, the 3gAllergy Specific IgE Universal Kit (Siemens). The clinical diagnoses of the 200 patients were included. In addition, a cross-reactive carbohydrate determinant (CCD)-inhibitor was used in the testing to decrease the incidence of positive CCD bands.ResultsThe mean overall agreement of all food and aeroallergens with the reference methods was 94.9%. Qualitative evaluation showed an average negative percent agreement of 98.9% and an average positive percent agreement of 75.1% for all individual allergens after testing with both reference methods. The additional treatment of samples with the CCD inhibitor successfully reduced the occurrence of positive CCD reactivity after retesting.ConclusionThe comparative analysis of RIDA qLine Allergy with the reference methods for specific IgE detection revealed a strong correlation between serum IgE levels measured across these platforms and clinical presentations, while also highlighting the necessity for careful contextual interpretation of results. Standardized allergen extracts would improve independent comparisons of different allergy testing methods.
The impact of pulmonary hypertension on prognosis in moderate-to-severe mitral regurgitation patients treated with transcatheter edge-to-edge mitral valve repair: a comprehensive meta-analysis
Authors: Wei Zhili , Shao Xinquan , An Zhijing , Chang Yixuan , Liu Shidong , Luo Ziran , Chen Yang , Song Bing 
Published: January 2025

ObjectiveThis meta-analysis aims to assess the impact of pulmonary hypertension (PH) on the clinical prognosis of patients with moderate to severe mitral valve regurgitation (MR) undergoing transcatheter edge-to-edge mitral valve repair (TEER).MethodsAs of August 2024, relevant studies were identified through searches of the PubMed, Cochrane Library, Web of Science, and Embase databases. A comprehensive screening process was conducted, with quality assessment performed utilizing the Newcastle Ottawa Scale (NOS). Data analysis was carried out using Stata17.0 software, generating forest plots, funnel plots, Egger's test, and sensitivity analysis plots to analyze heterogeneity and publication bias. Odds ratios (OR) and standardized mean differences (SMD) were calculated for dichotomous and continuous variables, respectively, each presented with a 95% confidence interval (CI).ResultsA total of 10 studies involving 28,404 patients were included, with all articles achieving a NOS score of ≥7. The outcome indicators were as follows: 2-year all-cause mortality [OR = 2.06, 95%CI(1.49, 2.84), p &lt; 0.01, I2 = 79.9%]; heart failure rehospitalization rate [OR = 1.56, 95%CI(1.29,1.76), p &lt; 0.01, I2 = 41.7%]; 30-day all-cause mortality [OR = 2.10, 95%CI(1.78,2.47), p &lt; 0.01, I2 = 0%]; cardiogenic mortality [OR = 2.00, 95%CI (1.61,2.49), p &lt; 0.01, I2 = 0%]; and length of hospital stay [OR = 0.17, 95%CI(0.14,0.20), p &lt; 0.01, I2 = 0%]. All outcome indicators demonstrated that the PH group had significantly worse outcomes compared to the non-PH group. Subgroup analyses were performed on outcome indicators with notable heterogeneity, focusing on PH measurement methods, PH diagnostic criteria, and the severity of PH. The results indicated that most combined subgroup outcomes were consistent with the overall findings and showed significantly reduced heterogeneity. The sources of heterogeneity are likely attributed to the methods of PH measurement, diagnostic criteria for PH, and the severity of PH.ConclusionWithin two years after undergoing transcatheter edge-to-edge repair (TEER), patients with MR and PH experiecne significantly higher rates of all-cause mortality, 30-day all-cause mortality, heart failure readmissions, cardiogenic mortality, and longer hospital stays compared to those without PH.Systematic Review Registrationhttps://inplasy.com/, identifier (INPLASY202480068).
Development of e-learning resources to enhance the pain education curriculum in physiotherapy programs using an action research-guided approach
Authors: Mathew Jerin , Rashid Muhammed , Shirsath Priyanka , Raja Kavitha 
Published: January 2025

IntroductionAmong healthcare professionals, Physiotherapists (PTs) are important members of pain management teams and are often the first contact clinicians. PTs must stay informed about the latest advancements in pain management to ensure effective practice. India graduates around 15,000 physiotherapy (PT) students annually, with over 20,000 PTs working in various institutions. However, the current pain curriculum needs to be updated, and resources need to be aligned with internationally accepted standards to improve the PT pain education program.MethodsA three-phase action research methodology (nominal group technique process) was adapted to identify gaps in pain science within the PT curricula of 30 universities in India. Experts used consensus methods to develop e-learning resources (Online and Instructional Digital Versatile Disks; DVDs) to address the gaps in curricula, following the IASP Curriculum Outline on Pain for Physical Therapy.ResultsA total of 22 h of pain lectures were recorded, and four DVDs were produced and duplicated for distribution. These DVDs were mailed to all universities and 469 individual institutions, with a recommendation for integration into undergraduate and postgraduate curricula. The lecture series was made freely accessible online through the institutional library repository.ConclusionWe employed an innovative method for content development based on the IASP curriculum, which involved consulting with experts and undergoing external peer review, leading to the development of e-learning resources. This project has initiated a ripple effect by providing evidence-based knowledge to young therapists and teaching faculty, with e-learning resources and materials readily accessible online. The resources created through this project could support ongoing pain management education for academic professionals and practicing PTs. This could facilitate evidence-based clinical practice and improve patient care.
A multivariable model of ultrasound and biochemical parameters for predicting high-volume lymph node metastases of papillary thyroid carcinoma with Hashimoto’s thyroiditis
Authors: Liu Xiao-hui , Yin Hong-qing , Shen Hong , Wang Xi-Ya , Zhang Zheng , Yuan Xiao-feng , Tang Qi , Shao Jun 
Published: January 2025

ObjectivesThis study aims to develop a nomogram to predict high-volume (&gt; 5) lymph node metastases (HVLNM) in papillary thyroid carcinoma concomitant with Hashimoto’s thyroiditis by combining ultrasound with clinicopathologic data.Materials and methodsThe study reviewed 187 patients diagnosed with papillary thyroid cancer (PTC) concomitant with Hashimoto’s thyroiditis from the First People’s Hospital of Kunshan between March 2018 and December 2022. These patients underwent preoperative ultrasound and postoperative examinations. They were divided into two groups based on the size of their lymph nodes (LNs). A predictive model was developed using LASSO regression and multifactor logistic regression analysis. The receiver operating characteristic (ROC) curve was used to validate the predictive model.ResultsA total of 187 patients were randomized into 132 participants for training and 55 participants for external validation. Four predictors including tumor size, extrathyroidal extension, histological grade and vascularity, were selected from 13 variables based on LASSO regression analysis. In the training set, the model built from the above four predictor has a satisfactory predictive power, with an area under the ROC curve of 0.914, and validation set with the ROC curve of 0.889, which indicated that the nomogram can be used effectively in clinical settings.ConclusionIn summary, the nomogram constructed by tumor size, extrathyroidal extension, histological grade and vascularity, is useful for predicting the risk of HVLNMs in patients with papillary thyroid carcinoma associated with Hashimoto’s thyroiditis, which is expected to provide the basis for adequate and accurate management before the primary surgery.
A vision-language model for predicting potential distribution land of soybean double cropping
Authors: Gao Bei , Liu Yuefeng , Li Yanli , Li Hongmei , Li Meirong , He Wenli 
Published: January 2025

IntroductionAccurately predicting suitable areas for double-cropped soybeans under changing climatic conditions is critical for ensuring food security anc optimizing land use. Traditional methods, relying on single-modal approaches such as remote sensing imagery or climate data in isolation, often fail to capture the complex interactions among environmental factors, leading to suboptimal predictions. Moreover, these approaches lack the ability to integrate multi-scale data and contextual information, limiting their applicability in diverse and dynamic environments.MethodsTo address these challenges, we propose AgriCLIP, anovel remote sensing vision-language model that integrates remote sensing imagery with textual data, such as climate reports and agricultural practices, to predict potential distribution areas of double-cropped soybeans under climate change. AgriCLIP employs advanced techniques including multi-scale data processing, self-supervised learning, and cross-modality feature fusion enabling comprehensive analysis of factors influencing crop suitability.Results and discussionExtensive evaluations on four diverse remote sensing datasets-RSICap RSIEval, MillionAID, and HRSID-demonstrate AgriCLIP’s superior performance over state-of-the-art models. Notably, AgriCLIP achieves a 97.54% accuracy or the RSICap dataset and outperforms competitors across metrics such as recall F1 score, and AUC. Its efficiency is further highlighted by reduced computation a demands compared to baseline methods. AgriCLIP’s ability to seamlessly integrate visual and contextual information not only advances prediction accuracy but also provides interpretable insights for agricultural planning and climate adaptation strategies, offering a robust and scalable solution for addressing the challenges of food security in the context of global climate change.
Mechanistic exploration of Traditional Chinese Medicine regulation on tumor immune microenvironment in the treatment of triple-negative breast cancer: based on CiteSpace and bioinformatics analysis
Authors: Feng Dandan , Pu Dongqing , Ren Jinlu , Liu Ming , Sun Xiaohui , Zhang Zhen , Li Jingwei 
Published: January 2025

BackgroundTriple-negative breast cancer (TNBC) is a highly aggressive subtype of breast cancer, characterized by frequent recurrence, metastasis, and poor survival outcomes despite chemotherapy-based treatments. This study aims to investigate the mechanisms by which Traditional Chinese Medicine (TCM) modulates the tumor immune microenvironment in TNBC, utilizing CiteSpace and bioinformatics analysis.MethodsWe employed CiteSpace to analyze treatment hotspots and key TCM formulations, followed by bioinformatics analysis to identify the main active components, targets, associated pathways, and their clinical implications in TNBC treatment.ResultsCiteSpace analysis highlighted key TCM formulations, including Sanhuang Decoction. Network pharmacology identified major bioactive components such as Mutatochrome, Physcion diglucoside, Procyanidin B-5,3’-O-gallate, gallic acid-3-O-(6’-O-galloyl)-glucoside, and isomucronulatol-7,2’-di-O-glucosiole, with core targets including Mitogen-Activated Protein Kinase 1 (MAPK1), Janus Kinase 2 (JAK2), and Lymphocyte-specific protein tyrosine kinase (LCK). These targets were found to be involved in immune regulation, particularly the modulation of CD8+ and CD4+ T cells. Additionally, core targets were associated with improved recurrence-free survival (RFS) and overall survival (OS) in TNBC patients.ConclusionThe therapeutic effects of TCM in TNBC primarily involve immune modulation within the tumor microenvironment, particularly through the regulation of CD8+ and CD4+ T cells.
Comparative efficacy and safety of different recommended doses of telitacicept in patients with systemic lupus erythematosus in China: a systematic review and meta-analysis
Authors: Gao Shenglan , Yang Chunlong , Huang Bitang , Yang Lawei , Lu Lu , Yang Huiting , Li Ting , Pan Qingjun 
Published: January 2025

BackgroundTelitacicept, a new biological agent, was approved in China for treating systemic lupus erythematosus (SLE) in 2021. Its optimal dosing for treating SLE remains unclear. Therefore, the aim of this meta-analysis is to evaluate the efficacy and safety of various telitacicept doses in SLE treatment.MethodsPubMed, EMBASE, Cochrane libraries, Web of science, China National Knowledge Infrastructure (CNKI), VIP, Wanfang, and Sinomed were searched for the controlled trials that studied the efficacy and safety of telitacicept on SLE patients from their initiation to April 30, 2024. The analysis included three randomized controlled trials (RCT) with 606 participants. We used fixed-effects models for meta-analyses and the risk ratios (RRs) and corresponding 95% confidence intervals (CIs) to evaluate the effectiveness and safety. Heterogeneity was assessed and quantified using I2.ResultsAll telitacicept dosages (80 mg, 160 mg, 240 mg) significantly improved SLE Responder Index 4 (SRI4) responses compared to the control group (RR = 2.20, 95%CI:1.50-3.21, p &lt; 0.0001; RR = 2.18, 95%CI: 1.82-2.62, p &lt; 0.00001; RR = 2.44, 95%CI: 1.67-3.56, p &lt; 0.00001, respectively). The 80 mg, 160 mg, and 240 mg groups also showed better improvement on SELENA-SLE Disease Activity Index (SELENA-SLEDAI) scores (RR = 1.63, 95%CI: 1.23-2.17, p = 0.0008; RR = 1.72, 95%CI: 1.45-2.04, p &lt; 0.00001; RR = 1.73, 95%CI: 1.30-2.30, p = 0.0002, respectively) and Physician Global Assessment (PGA) scores (RR = 1.25, 95%CI: 1.09-1.44, p = 0.002; RR = 1.39, 95%CI: 1.25-1.55, p &lt; 0.00001; RR = 1.24, 95%CI: 1.09-1.42, p = 0.002, respectively). Furthermore, 160 mg group exhibited higher British Isles Lupus Assessment Group (BILAG) score than the control group (RR = 1.11, 95%CI: 1.01-1.22, p = 0.03). As for security, 160 mg telitacicept group had higher incidence of adverse events (AEs) than the control group (RR = 1.10, 95%CI: 1.03-1.18, p = 0.007).ConclusionTelitacicept combined with standard therapy presents potential benefits but there are certain safety concerns with certain dosages of telitacicept, warranting further investigation for optimal dosing strategies in SLE management.Systematic review registrationINPLASY.COM, identifier INPLASY202440101.
Hepatic arterial infusion chemotherapy combined with immune checkpoint inhibitors and molecular targeted therapies for advanced infiltrative hepatocellular carcinoma: a single-center experience
Authors: Wang Zizhuo , Song Songlin , Zhang Lijie , Yang Tingting , Yao Wei , Liang Bin 
Published: January 2025

BackgroundInfiltrative hepatocellular carcinoma (HCC) remains a therapeutic challenge due to its aggressive course and poor prognosis. Hepatic arterial infusion chemotherapy (HAIC) plus immune checkpoint inhibitors (ICIs) and molecular targeted therapies (MTTs) has shown early promise for advanced HCC, but its role in advanced infiltrative HCC is unclear. This study aims to investigate the efficacy and safety of HAIC combined with ICIs and MTTs in the treatment of advanced infiltrative HCC.MethodsPatients with infiltrative HCC initially treated with HAIC plus ICIs and MTTs were consecutively included at our institution from November 2021 to June 2023. The efficacy evaluation included tumor response, time to response (TTR), duration of response (DOR), progression-free survival (PFS) per RECIST 1.1, and patient survival. Adverse events (AEs) were recorded for safety evaluation.ResultsA total of 27 patients were included and the median follow-up was 15.8 months (range, 4.3–25.9). The best objective response rate (ORR) and disease control rate (DCR) were 70.4% and 88.9%, respectively. The median TTR was 2.8 months (95% confidence interval [CI], 2.6–3.0) and the median DOR was 7.9 months (95% CI, 3.2–12.5). The median PFS was 7.5 months (95% CI, 4.2–10.7), and the median overall survival (OS) was 16.8 months (95% CI, 14.0–19.6), with a 1-year OS rate of 74.1%. No cases of grade 4 or 5 treatment-related adverse events (TRAEs) were observed in this study. Grade 3 TRAEs occurred in 17/27 (63.0%) patients, and the predominant grade 3 treatment-related adverse events were lymphocyte count decreased (18.5%) and neutrophil count decreased (14.8%).ConclusionsThe combination of HAIC plus ICIs and MTTs demonstrated encouraging outcomes and manageable safety concerns for infiltrative HCC.