bluuebunny/crossref_metadata_2025_split huggingface dataset:
Leveraging health infrastructure to optimize HPV vaccination for adolescents in Zambia: Protocol for an implementation study
Authors: Miti Sam , Shato Thembekile , Asante Comfort , Baumann Ana , Chongwe Gershom , Bobo Patricia M. , Silver Michelle I. , Hunleth Jean M. 
Published: May 2023

BackgroundCervical cancer is the leading cause of cancer death in Zambia, where HIV prevalence is also high (11.3%). HIV heightens the risk of developing and dying from cervical cancer. The human papillomavirus (HPV) vaccine can prevent 90% of cervical cancers, and in Zambia is recommended for adolescent girls ages 14–15 years, including those with HIV. Currently they mainly deliver HPV vaccination via school-based campaigns, which may exclude the most vulnerable adolescents—those out-of-school or who irregularly attend. Adolescents living with HIV (ALHIV) are more likely to have these vulnerabilities. Further, school-based campaigns are not tailored to the WHO-recommended HPV vaccination schedule for ALHIV (3 versus 2 doses). Integrating HPV vaccination into routine care in adolescent HIV clinics may ensure that ALHIV have access to vaccine at the WHO-recommended schedule. Such integration requires a multilevel approach, stakeholder engagement, and diversified implementation strategies, given known challenges of providing the HPV vaccine in LMICs, including Zambia.MethodsOur study aims to integrate HPV vaccination into routine care in adolescent HIV clinics. To achieve success, we will co-design a package of implementation strategies using a previously successful implementation research approach developed for cervical cancer prevention in LMICs: the Integrative Systems Praxis for Implementation Research (INSPIRE). INSPIRE is a novel, comprehensive approach to develop, implement, and evaluate implementation science efforts. Following key elements of INSPIRE, our specific aims are to: 1) Identify the unique multilevel contextual factors (barriers and facilitators) across HIV settings (rural, urban, peri-urban) that influence HPV vaccine uptake; 2) Use Implementation Mapping to translate stakeholder feedback and findings from Aim 1 into a package of implementation strategies to integrate HPV vaccine into HIV clinics; 3) Conduct a Hybrid Type 3 effectiveness-implementation trial to evaluate the package of multilevel implementation strategies for integrating HPV vaccine into HIV clinics.DiscussionOur research team has strong support, technical expertise, and resources (e.g., vaccines) from the Zambian Ministry of Health; and political will for scale-up. This stakeholder-based implementation model has the potential to be transported to HIV clinics across Zambia and serve as a model to address cancer prevention priorities for those with HIV in other LMICs.Trial registrationTo be registered prior to Aim 3, when implementation strategies finalized.
Timing of perinatal death; causes, circumstances, and regional variations among reviewed deaths in Ethiopia
Authors: Tesfay Neamin , Tariku Rozina , Zenebe Alemu , Hailu Girmay , Taddese Muse , Woldeyohannes Fitsum 
Published: May 2023

Introduction
Ethiopia is one of the countries facing a very high burden of perinatal death in the world. Despite taking several measures to reduce the burden of stillbirth, the pace of decline was not that satisfactory. Although limited perinatal mortality studies were conducted at a national level, none of the studies stressed the timing of perinatal death. Thus, this study is aimed at determining the magnitude and risk factors that are associated with the timing of perinatal death in Ethiopia.

Methods
National perinatal death surveillance data were used in the study. A total of 3814 reviewed perinatal deaths were included in the study. Multilevel multinomial analysis was employed to examine factors associated with the timing of perinatal death in Ethiopia. The final model was reported through the adjusted relative risk ratio with its 95% Confidence Interval, and variables with a p-value less than 0.05 were declared statistically significant predictors of the timing of perinatal death. Finally, a multi-group analysis was carried out to observe inter-regional variation among selected predictors.

Result
Among the reviewed perinatal deaths, 62.8% occurred during the neonatal period followed by intrapartum stillbirth, unknown time of stillbirth, and antepartum stillbirth, each contributing 17.5%,14.3%, and 5.4% of perinatal deaths, respectively. Maternal age, place of delivery, maternal health condition, antennal visit, maternal education, cause of death (infection and congenital and chromosomal abnormalities), and delay to decide to seek care were individual-level factors significantly associated with the timing of perinatal death. While delay reaching a health facility, delay to receive optimal care health facility, type of health facility and type region were provincial-level factors correlated with the timing of perinatal death. A statistically significant inter-regional variation was observed due to infection and congenital anomalies in determining the timing of perinatal death

Conclusion
Six out of ten perinatal deaths occurred during the neonatal period, and the timing of perinatal death was determined by neonatal, maternal, and facility factors. As a way forward, a concerted effort is needed to improve the community awareness of institutional delivery and ANC visit. Moreover, strengthening the facility level readiness in availing quality service through all paths of the continuum of care with special attention to the lower-level facilities and selected poor-performing regions is mandatory.
Integrative Arts Psychotherapy: Using an Integrative Theoretical Frame and the Arts in Psychotherapy, Claire Louise Vaculik and Gary Nash (Eds) (2022)
Authors: Westling Colleen Steiner 
Published: May 2023

Review of: Integrative Arts Psychotherapy: Using an Integrative Theoretical Frame and the Arts in Psychotherapy, Claire Louise Vaculik and Gary Nash (Eds) (2022)
Abingdon: Routledge, 250 pp.,
ISBN 978-0-36772-636-2, p/bk, £24.99
Eye-tracking technology in automotive industry
Authors: Novotný Jan , Machan Jaroslav , Orlický Adam 
Published: May 2023

The research paper „Eye-tracking technology in automotive industry“ describes the implementation of eye-tracking technology into the development of new vehicles and their decision-making process. This objective technology tracks the eye movement of a participant, detects where the subject is looking during an interval of an experiment, and thus offers a wide range of applications. It can be used to detect distractions while driving on a simulator under a certain workload or to record objective data during an otherwise subjective customer-oriented clinic. In this topic, we evaluate areas of the vehicle which are the most interesting for customers, and therefore provide support and recommendations for new vehicle designs.
Bridging Al-Dunya Wa Al-Diin: A Case Study on Prophetic-Integrative Education on Madrasah-Based Pesantren
Authors: 'Aziz Hafidh 
Published: May 2023

Purpose – This study aims to analyze the practice of integrating education in Islamic boarding schools based on the perspective of prophetic education.
Design/methods/approach – This study used a case study design and was conducted in Madrasah Tsanawiyah and Aliyah Modern Boarding School (PM) Al-Islam. Data were collected using interview observations and documentation and then analyzed using the Miles and Huberman interactive model.
Findings – This study’s findings show that the spirit and practice of education in Madrasah Tsanawiyah and Aliyah Al-Islam align with prophetic values by prioritizing transcendent spirituality with critical humanist principles framed in the form of institutional integration and content.
Research implications/limitations – This study strengthens and complements previous research findings on integrating Islamic scholarship in Islamic educational institutions in Indonesia. However, it is also important to continue conducting similar research with a broader scope to strengthen related research findings.
Practical implications – The findings of this study can be a bridge to close the dichotomous gap and balance the gap in educational orientation to achieve educational goals between religious and pragmatic educational goals.
Freedom to Learn – Independent Campus (MBKM) Curriculum Management at the Indonesian Language Tadris Degree Program (TBI) of Islamic Religious Higher Education Institutions (PTKI)
Authors: Isnaniah Siti , Kurniawan Kurniawan 
Published: May 2023

Purpose – This study aims to explain the management of the MBKM curriculum in the TBI Degree Program at PTKI and the implementation of forms of collaboration with partners who support the MBKM program’s implementation. The data was gathered from the TBI Degree Program at UIN Raden Mas Said (RMS) Surakarta.
Design/methods/approach – This study employs a qualitative explanatory method. Documents, informants, and events serve as data sources. Data collection methods included content/document analysis, in-depth interviews, and observation. The data analysis technique employs an interactive model. The triangulation technique is used in the data validity technique.
Findings – The results show that the MBKM Degree Program curriculum design at UIN RMS Surakarta has incorporated 21st-century skills. Several courses will require digital skills, such as Digital Literacy, Monetization of Digital Products, and Development of Indonesian Language Learning Media starting in 2019. TBI’s Degree Program, Starting in 2019 in support of MBKM, has also implemented collaboration with various partners, including the Industrial World Business World (DUDI).
Research implications/limitations – This research contributes to understanding the importance of implementing MBKM in the TBI Degree Program at PTKI, with the data source being the TBI Degree Program Faculty of Adab and Language at UIN Raden Mas Said Surakarta. It can be used as a model for other TBI Degree Programs at PTKI that have not implemented MBKM much. in designing the curriculum.
Practical implications – This research can provide practical training in the Indonesian Tadris curriculum and a curriculum review for MBKM design.
Trensains: The New Pesantren and Shifting Orientation of Islamic Education in Indonesia
Authors: Azaki Khoirudin  , Abdul Munip  , Imam Machali  , Hamzah Fansuri  
Published: May 2023

Purpose – This study aims to explain the factors of the emergence of “pesantren sains/science pesantren” (Trensains) and their implications for the shift in the orientation of Islamic education in Indonesia. Existing pesantren studies have looked more at practical aspects, such as curriculum development and learning, but not yet at philosophical aspects, which have implications for a shift in the orientation of Islamic education.
Design/methods/approach – Data was collected using interviews and documentation. The research, which utilized a phenomenological approach, was conducted at Sragen Muhammadiyah Trensains Senior High School in Central Java and Tebuireng Trensains Senior High School in East Java. The primary respondent was Agus Purwanto, the initiator, founder, and developer of a science boarding school, who had first-hand experience with the events that took place while he was a student at the Pesantren.
Findings – The findings of this study suggest that Trensains is a new pesantren genre that was developed as a reaction to the lack of science and technology in the Islamic world due to the heavy jurisprudential emphasis on Islamic education. In the history of the curricula at pesantren, including philosophy as a topic is a novelty.
Research implications/limitations – The emergence of Trensains has implications for a shift in the orientation of pesantren in Indonesia from a Sufistic-fiqh orientation to a scientific-philosophical orientation which is marked by the following changes: (1) in the function of transmission and transfer of Islamic knowledge (tafaqquh fī al-dīn) to the study of Islamic sciences general science; (2) from maintaining the Islamic tradition to cultivating the scientific tradition; and (3) from a reproduction of religionists to producers of scientists. However, some drawbacks need to be acknowledged. This study has not discussed Trensains as a whole, and its effectiveness in shaping the character of pesantren is unknown. Therefore, further research is needed to understand the impact and role of Trensains in the development of Islamic education in Indonesia.
Rhythmic Information Sampling in the Brain during Visual Recognition
Authors: Caplette Laurent , Jerbi Karim , Gosselin Frédéric 
Published: May 2023

When we fixate an object, visual information is continuously received on the retina. Several studies observed behavioral oscillations in perceptual sensitivity across such stimulus time, and these fluctuations have been linked to brain oscillations. However, whether specific brain areas show oscillations across stimulus time (i.e., different time points of the stimulus being more or less processed, in a rhythmic fashion) has not been investigated. Here, we revealed random areas of face images at random moments across time and recorded the brain activity of male and female human participants using MEG while they performed two recognition tasks. This allowed us to quantify how each snapshot of visual information coming from the stimulus is processed across time and across the brain. Oscillations across stimulus time (rhythmic sampling) were mostly visible in early visual areas, at theta, alpha, and low beta frequencies. We also found that they contributed to brain activity more than previously investigated rhythmic processing (oscillations in the processing of a single snapshot of visual information). Nonrhythmic sampling was also visible at later latencies across the visual cortex, either in the form of a transient processing of early stimulus time points or of a sustained processing of the whole stimulus. Our results suggest that successive cycles of ongoing brain oscillations process stimulus information incoming at successive moments. Together, these results advance our understanding of the oscillatory neural dynamics associated with visual processing and show the importance of considering the temporal dimension of stimuli when studying visual recognition.SIGNIFICANCE STATEMENTSeveral behavioral studies have observed oscillations in perceptual sensitivity over the duration of stimulus presentation, and these fluctuations have been linked to brain oscillations. However, oscillations across stimulus time in the brain have not been studied. Here, we developed an MEG paradigm to quantify how visual information received at each moment during fixation is processed through time and across the brain. We showed that different snapshots of a stimulus are distinctly processed in many brain areas and that these fluctuations are oscillatory in early visual areas. Oscillations across stimulus time were more prevalent than previously studied oscillations across processing time. These results increase our understanding of how neural oscillations interact with the visual processing of temporal stimuli.
Active Zone Trafficking of CaV2/UNC-2 Channels Is Independent of β/CCB-1 and α2δ/UNC-36 Subunits
Authors: Oh Kelly H. , Xiong Ame , Choe Jun-yong , Richmond Janet E. , Kim Hongkyun 
Published: May 2023

The CaV2 voltage-gated calcium channel is the major conduit of calcium ions necessary for neurotransmitter release at presynaptic active zones (AZs). The CaV2 channel is a multimeric complex that consists of a pore-forming α1subunit and two auxiliary β and α2δ subunits. Although auxiliary subunits are critical for channel function, whether they are required for α1trafficking is unresolved. Using endogenously fluorescent protein-tagged CaV2 channel subunits inCaenorhabditis elegans, we show that UNC-2/α1localizes to AZs even in the absence of CCB-1/β or UNC-36/α2δ, albeit at low levels. When UNC-2 is manipulated to be trapped in the endoplasmic reticulum (ER), CCB-1 and UNC-36 fail to colocalize with UNC-2 in the ER, indicating that they do not coassemble with UNC-2 in the ER. Moreover, blocking ER-associated degradation does not further increase presynaptic UNC-2 channels inccb-1orunc-36mutants, indicating that UNC-2 levels are not regulated in the ER. Anunc-2mutant lacking C-terminal AZ protein interaction sites with intact auxiliary subunit binding sites displays persistent presynaptic UNC-2 localization and a prominent increase of UNC-2 channels in nonsynaptic axonal regions, underscoring a protective role of auxiliary subunits against UNC-2 degradation. In the absence of UNC-2, presynaptic CCB-1 and UNC-36 are profoundly diminished to barely detectable levels, indicating that UNC-2 is required for the presynaptic localization of CCB-1 and UNC-36. Together, our findings demonstrate that although the pore-forming subunit does not require auxiliary subunits for its trafficking and transport to AZs, it recruits auxiliary subunits to stabilize and expand calcium channel signalosomes.SIGNIFICANCE STATEMENTSynaptic transmission in the neuron hinges on the coupling of synaptic vesicle exocytosis with calcium influx. This calcium influx is mediated by CaV2 voltage-gated calcium channels. These channels consist of one pore-forming α1subunit and two auxiliary β and α2δ subunits. The auxiliary subunits enhance channel function and regulate the overall level of channels at presynaptic terminals. However, it is not settled how these auxiliary subunits regulate the overall channel level. Our study inC. elegansfinds that although the auxiliary subunits do not coassemble with α1and aid trafficking, they are recruited to α1and stabilize the channel complex at presynaptic terminals. Our study suggests that drugs that target the auxiliary subunits can directly destabilize and have an impact on CaV2 channels.
Developing English Material For Sharia Economy Study Program at IAIN Palopo
Authors: Furwana Dewi , Hartine St. 
Published: May 2023

The purpose of this developmental research is to develop English material for Sharia Economy Study Program. It aims to determine the textbooks' feasibility, and to ascertain students' responses to the ESP textbooks. The ADDIE Research and Development (RD) model is used in this study. The feasibility study of the ESP textbook reveals the following points: 1)The result of validation from the material expert validation was 94,11 % qualified as “Very good”,the language expert was 80% qualified as “Good.”, and the layout expert was 92,4% qualified as “Very Good.”. In addition, the students’ perception results got a mean score of 4,28 with 86% of the percentage, which qualified as “ Very Good”. The final product consists 10 chapter with 10 exercises of each chapter. The developed textbook has a lot of strengths because it was created using a combination of syllabus design principles. a single unit presentation includes all four essential English skills: listening, speaking, reading, and writing, as well as grammar practice and vocabulary building. It indicates that the English material is capable and ready to use for Sharia Economic Study Program at IAIN Palopo.
Ensuring Early Childhood Children’s Right to a Safe and Healthy Family Life
Authors: Lebedzinskiene Lijana , Bilbokaitė-Skiauterienė Ieva 
Published: May 2023

The theoretical insights into the problem under analysis allow us to state that, in the context of constant changes in social life, people’s thinking and habits as well as the problem of protecting children’s rights in the family remain topical and in need of further research. It is therefore appropriate to explore in more depth how parents perceive their responsibilities and opportunities in guaranteeing the right of the early child to grow up healthy and safe, what problems they face and how they deal with them. The aim of the study is to reveal parents’ views on the right of the early years’ child to a safe and healthy family life. The study is based on the following conceptual frameworks: the Social Construction of Reality Theory (Berger, Luckmann, 1999) and the Child-Centred Educational Paradigm (Dewey, 1961; Juodaitytė, 2003; Monkevičienė, 2008). The qualitative approach was used in the study, the choice of which was determined by the specificity of the analyzed problem and personal preference for qualitative research. The following research methods were employed: the analysis of scientific literature, normative documents containing information about the research object; semi-standardized interview. The content analysis method was used to analyse the research data. Seven parents of early childhood children participated in the study.
On the basis of the theoretical insights and the results of the qualitative research, it can be concluded that the parents who participated in the study are aware of their responsibility and potential in ensuring the child’s right to grow up healthy and safe, and they understand the significance of this right for the child’s personality. The results obtained provide an opportunity for further analysis of the right of the early childhood child to grow up healthy and safe, and to gain insight into the parents’ experiences in this aspect. Parents aim to raise their children’s awareness of the importance of a healthy lifestyle, proper nutrition, physical activity, participation in their children’s lives, creating a sense of security and ensuring a supportive home environment.
The Pediatrician Workforce in the United States and China
Authors: Russ Christiana M. , Gao Yijin , Karpowicz Kristin , Lee Shoo , Stephens Timothy Noel , Trimm Franklin , Yu Hao , Jiang Fan , Palfrey Judith 
Published: May 2023

Abstract
From 2019 to 2022, the For Our Children project gathered a team of Chinese and American pediatricians to explore the readiness of the pediatric workforce in each country to address pressing child health concerns. The teams compared existing data on child health outcomes, the pediatric workforce, and education and combined qualitative and quantitative comparisons centered on themes of effective health care delivery outlined in the World Health Organization Workforce 2030 Report. This article describes key findings about pediatric workload, career satisfaction, and systems to assure competency. We discuss pediatrician accessibility, including geographic distribution, practice locations, trends in pediatric hospitalizations, and payment mechanisms. Pediatric roles differed in the context of each country’s child health systems and varied teams. We identified strengths we could learn from one another, such as the US Medical Home Model with continuity of care and robust numbers of skilled clinicians working alongside pediatricians, as well as China’s Maternal Child Health system with broad community accessibility and health workers who provide preventive care.
In both countries, notable inequities in child health outcomes, evolving epidemiology, and increasing complexity of care require new approaches to the pediatric workforce and education. Although child health systems in the United States and China have significant differences, in both countries, a way forward is to develop a more inclusive and broad view of the child health team to provide truly integrated care that reaches every child. Training competencies must evolve with changing epidemiology as well as changing health system structures and pediatrician roles.