bluuebunny/crossref_metadata_2025_split huggingface dataset:
Improving the Rate of Delayed Cord Clamping in Preterm Infants: A Quality Improvement Project
Authors: Chan Shannon , Duck Meghan , Frometa Kate , Liebowitz Melissa , Rosenstein Melissa G. , Tesfalul Martha , Cornet Marie-Coralie , Kramer Katelin P. 
Published: March 2023

OBJECTIVE
Delayed cord clamping (DCC) provides many benefits for preterm infants. The aim of this quality improvement project was to increase the rate of DCC by 25% within 12 months for neonates &lt;34 weeks’ gestation born at a tertiary care hospital.

METHOD
A multidisciplinary team investigated key drivers and developed targeted interventions to improve DCC rates. The primary outcome measure was the rate of DCC for infants &lt;34 weeks’ gestation. Process measures were adherence to the DCC protocol and the rate of births with an experienced neonatology provider present at the bedside. Balancing measures included the degree of neonatal resuscitation, initial infant temperature, and maternal blood loss. Data were collected from chart review and a perinatal research database and then analyzed on control charts. The preintervention period was from July 2019 to June 2020 and the postintervention period was from July 2020 to December 2021.

RESULTS
322 inborn neonates born at &lt;34 weeks’ met inclusion criteria (137 preintervention and 185 postintervention). The rate of DCC increased by 63%, from a baseline of 40% to 65% (P &lt;.001), with sustained improvement over 18 months. Significant improvement occurred for all process measures without a significant change in balancing measures.

CONCLUSION
Using core quality improvement methodology, a multidisciplinary team implemented a series of targeted interventions which was associated with an increased rate of DCC in early preterm infants.
TÉCNICAS FISIOTERAPÉUTICAS MÁS UTILIZADAS EN LA ARTROPLASTIA TOTAL DE RODILLA Y CALIDAD DE SU EVIDENCIA: REVISIÓN SISTEMÁTICA 2010-2020
Authors: Vargas Martínez Brenda Pamela , Restrepo Chacón Ana Karolina , Alfaro Redondo César 
Published: March 2023

La Artroplastia Total de Rodilla (ATR) es una cirugía que reemplaza la articulación dañada -rótula, cara articular distal del fémur y cara articular proximal de la tibia- con partes artificiales conocidas como prótesis. Esta cirugía requiere un abordaje fisioterapéutico paralelo que permita recuperar la mayor independencia funcional. Dada la variedad de intervenciones fisioterapéuticas posibles de implementar, resulta importante identificar aquellas que cuentan con mayor evidencia científica. El objetivo de la investigación realizada fue identificar las técnicas fisioterapéuticas más utilizadas en la Artroplastia total de rodilla y la calidad de su evidencia, a través de una revisión sistemática 2010-2020. Se realizó una revisión sistemática tomando como base las especificaciones estipuladas en una guía clínica de atención. Se revisaron 40 artículos científicos en los que se identificaron cuatro intervenciones fisioterapéuticas: modalidades electro terapéuticas, agentes físicos, ejercicio terapéutico, movilizaciones pasivas y otras intervenciones fisioterapéuticas. Además, se obtuvo que un 27,5 % de los artículos presentaron calidad de ++++, un 42,5 % calidad de +++, un 17,5 % calidad ++ y un 12,5 % con calidad de +. Como conclusión se destaca que un poco menos de la mitad de los estudios obtuvieron calidad de +++ o calidad moderada, lo cual podría estar relacionado con la falta de rigurosidad en las metodologías de investigación de los estudios o la escasez en investigaciones en el área. Ambas situaciones dejan en evidencia el reciente crecimiento que tiene la carrera en relación con la actividad investigativa y la necesidad de orientarla hacia la atención basada en evidencia.
Palabras clave: Modalidades de Fisioterapia, Práctica Clínica basada en la evidencia, Artroplastia de reemplazo de rodilla, Rehabilitación. Fuente: DeCS/MeSH.
NEUMOTÓRAX, NEUMOMEDIASTINO, NEUMOPERITONEO Y ENFISEMA SUBCUTÁNEO POR PERFORACIÓN COLÓNICA DURANTE COLONOSCOPIA EN UN HOSPITAL RURAL DE COSTA RICA
Authors: Navarro Coto José Francisco , Molina Guerrero Miguel Antonio , Ledezma Cabezas Andrea 
Published: March 2023

El presente estudio tiene como finalidad reportar un caso que inició a partir de una lesión iatrogénica en un procedimiento endoscópico. Las patologías subsecuentes a la perforación colónica constituyeron un alto riesgo de muerte en el contexto de un paciente de 89 años. La colonoscopia ha sido el método de estudio de elección para el diagnóstico de alguna patología maligna o benigna en el colon. La perforación durante el procedimiento es infrecuente, pero sus repercusiones son muy serias. El diagnóstico del neumotórax hipertensivo es clínico y no debería requerir algún examen de laboratorio o imagen para su diagnóstico. Además, un rápido abordaje permite cambiar la evolución del paciente. Durante la realización de una colonoscopia electiva, el paciente inicia con una dificultad respiratoria, lo que causó un paro cardiorrespiratorio con actividad eléctrica sin pulso. Un pronto diagnóstico de neumotórax hipertensivo permitió que se volviera a ritmo sinusal y se continuara con el manejo de lo que a todas luces se trataba de una perforación colónica. El manejo de patología compleja en un hospital rural es un reto en la evolución de pacientes. Por lo tanto, las complicaciones de los procedimientos endoscópicos, generadas y resueltas con éxito, demuestran que el trabajo interdisciplinario, así como el ejercicio diario de la clínica sobre los estudios tecnológicos, hacen que, aún más, este caso sobresalga dentro del ambiente científico.
Palabras clave: Colonoscopía, Neumotórax, Neumomediastino, Neumoperitoneo. Fuente:DeCS/MeSH
Accelerated curing effects on performance of metakaolin concrete
Authors: Dubey Moulshree , Deo Shirish V. , Ramtekkar Gangadhar 
Published: March 2023

AbstractThe manufacturing of cement liberates the green-house gasses into atmosphere. To overcome this problem so many alternative materials has been invented by researchers to minimize addition of cement. The incorporation of these alternative materials as cementitious material in concrete enhances the attributes of concrete. In this scenario metakaolin gained momentum as a substitution to cement in concrete. Most of the researchers studied the performance of concrete incorporating metakaolin as cementitious material in normal curing conditions. There is a need for analysing the impact of accelerated curing on properties of concrete by incorporating metakaolin as cementitious material. The current construction industry needs high early strength for removal of form work in early ages. The accelerated curing is a method which provides high early strength. In this study, different proportions of metakaolin are added as partial alternative to cement and cured in accelerated curing tank for 3.5 h. The strength parameters test, durability test, and micro-structural parameter tests are performed on these samples. Further, micro-structural analysis has been carried out using SEM, and EDX tests. Results depicted the incorporation of 15% of metakaolin as substitute to cement amplifies the overall performance of concrete in accelerated curing regime.
Bibliometric Networks and financing in Brazilian Physical Education Research
Authors: Pimentel Daniel , Pimentel Felipe , McManus Concepta 
Published: March 2023

In this paper, we looked at citations, major institutions, research themes and funding in physical education and sports studies from Brazilian authors to evaluate their impact and insertion worldwide. A bibliometric analysis using data from international (Web of Science and Scopus) and national (Sucupira) databases followed by visualization of similarities. Data was downloaded from Scopus and SciVal (Elsevier) and Web of Science (Clarivate Analytics) databases as well as Sucupira in the area of Physical Education as defined by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior in Brazil. Data were analysed using Visualisation of Similarities (Vosviewer), correlation, regression and variance analyses to examine the relationship between quantity and quality indicators. Major topics researched include obesity, exercise, joints, cartilage, tendons and muscles (ankle, knee, hip, shoulder) as well as factors linked to age (child, adolescent and ageing), in line with those researched worldwide. The correlation between the number of publications per topic worldwide and in Brazil is 0.79. There was a concentration of publishing in the area of physical education in Brazil with 80% of papers being published by only 12% of the institutions that publish on this subject. Brazilian authors in physical education cooperate with, and receive financing from, institutions and funding agencies worldwide, but papers funded by Brazilian agencies have lower impact. Brazilian researchers are researching similar topics to international researchers, but citation analysis shows relatively closed clusters of researchers with little interaction between them.
Reorganizing as a Covid-Free Heart Center: Does It Really Matter For The Primary Percutaneous Coronary Intervention Endpoints During the Covid-19 Pandemic?
Authors: ÖZYILDIRIM Serhan 
Published: March 2023

Backrounds/Aims: With the emergence of the new and more transmissible COVID variants such as Omicron, the necessity of taking new measures began to be discussed.
Methods: Data regarding the organizational arrangements as defining COVID-free heart centers during the first waves is scarce. We evaluated the 273 non-COVID acute coronary syndrome patients who were admitted to our COVID-free tertiary cardiovascular center during the lockdown period. None of these cases had hospital acquired SARS CoV-2 infection during the follow-up. Therefore, no COVID-related morbidity or mortality was observed in this vulnerable group.
Results: However, when we analyzed the 88 primary percutaneous coronary intervention procedures of the non-COVID STEMI patients of the lockdown period and compared the 70 of them with the 50 STEMI patients of the previous year, the results were not that encouraging. Even our hospital was declared as a COVID-free cardiolovascular center, there was a significant delay in the symptom-to-door time (SDT) during the pandemic (4.8 vs. 2.5 hours, respectively; P
Radiosurgical interventions in the prevention of post-resection liver failure
Authors: Melekhina O. V. , Musatov A. B. , Kulezneva J. V. , Efanov M. G. , Tsvirkun V. V. , Alikhanov R. B. , Amkhadov E. O. , Sadykov B. A. , Kantimerov D. F. , Salnikov K. K. 
Published: March 2023

Aim. To evaluate the effectiveness of percutaneous ALPPS as a method for preventing post-resection liver failure.Materials and methods. The methodology involved a retrospective study of the results of portovenous embolization and percutaneous radiofrequency assisted liver partition with portal vein embolization (PRALLPS), in case of the future liver volume <40% . The degree of hypertrophy of the future liver remnant and its rate were assessed in two groups. Complications of manipulation and frequency of postresection hepatic failure were studied.Results. In the first stage, portenous embolization was successfully performed in 38 patients and PRALLPS was successfully performed in 47 patients. In the second stage, liver resection was performed in 27 (71.1%) and 33 (70%) patients. The most frequent complication of PRALLPS was bile accumulation in the radiofrequency ablation area (13.1%). The incidence of other complications of the first stage did not differ between groups. No differences in blood loss or incidence of liver failure were reported after the second stage. No fatal outcomes reported. The mean degree of hypertrophy and growth did not differ between the groups. The mean time of hypertrophy of the future liver remnant after percutaneous radiofrequency assisted partition of the parenchyma with portal vein embolization and portenous embolization was 13 ± 5 and 18 ± 7 days (p = 0.008).Conclusion. The results of percutaneous radiofrequency assisted liver partition with portal vein embolization are comparable in terms of safety with those of portenous embolization. Radiofrequency partition of the parenchyma with portal vein embolization enables optimal hypertrophy of the future liver remnant to be achieved faster.
Determinants of a decline in a nutrition risk measure differ by baseline high nutrition risk status: targeting nutrition risk screening for frailty prevention in the Canadian Longitudinal Study on Aging (CLSA)
Authors: Keller Heather H. , Trinca Vanessa 
Published: March 2023

Abstract
Objectives
Nutrition risk is a key component of frailty and screening, and treatment of nutrition risk is part of frailty management. This study identified the determinants of a 3-year decline in nutrition risk (measured by SCREEN-8) for older adults stratified by risk status at baseline.

Methods
Secondary data analysis of the comprehensive cohort sample of the Canadian Longitudinal Study on Aging (CLSA) (n = 5031) with complete data for covariates at baseline and 3-year follow-up. Using a conceptual model to define covariates, determinants of a change in nutrition risk score as measured by SCREEN-8 (lower score indicates greater risk) were identified for those not at risk at baseline and those at high risk at baseline using multivariable regression.

Results
Models stratified by baseline nutrition risk were significant. Notable factors associated with a decrease in SCREEN-8 for those not at risk at baseline were mental health diagnoses (− 0.83; CI [− 1.44,  −0.22]), living alone at follow-up (− 1.98; CI [− 3.40,  −0.56]), and lack of dental care at both timepoints (− 0.91; CI [− 1.62,  −0.20]) and at follow-up only (− 1.32; CI [− 2.45,  −0.19]). For those at high nutrition risk at baseline, decline in activities of daily living (− 2.56; CI [− 4.36,  −0.77]) and low chair-rise scores (− 1.98; CI [− 3.33, − 0.63]) were associated with lower SCREEN-8 scores at follow-up.

Conclusion
Determinants of change in SCREEN-8 scores are different for those with no risk and those who are already at high risk, suggesting targeted approaches are needed for screening and treatment of nutrition risk in primary care.
A CONSTRUÇÃO DO FEMININO EUROPEU NOS SÉCULOS XVIII E XIX: CONTRIBUIÇÕES DA MARQUESA DE ALORNA
Authors: Valadares de Godoy Gislaine Aparecida 
Published: March 2023

Esse artigo apresenta uma análise de conteúdo baseada nos escritos de Bardin (2009) acerca dos princípios educativos femininos presentes em um conjunto de seis cartas da poetisa portuguesa conhecida como Marquesa de Alorna, escritas no século XVIII e endereçadas a uma filha que estava para se casar. A análise buscou considerar os princípios sugeridos pela marquesa, presentes nas referidas cartas, como uma ‘proposta formativa’ em contraposição ao projeto educativo vigente da época, que conduziam as mulheres para serem administradoras do lar, mães e esposas atenciosas. Nas orientações ofertadas a filha, identificamos um possível ‘novo perfil’ feminino surgindo na sociedade da época.Nossa hipótese, é que a marquesa teria sido uma das pioneiras na construção desse novo perfil, ao qual denominamos de ‘o desabrochar’ da consciência feminina, levando, posteriormente, a emancipação feminina a partir de um importante aliado, a instrução. Tomamos a marquesa, ao mesmo tempo, como exemplo dessa construção e uma das responsáveis por esse processo em outras mulheres, seja direta ou indiretamente. Como resultado dessa análise, verificamos que de fato, houve uma mudança na forma de pensar de algumas mulheres daquele período, das que tiveram acesso aos ensinamentos da marquesa ou outra forma de instrução. E, essa modificação, proporcionou à essas mulheres que se reconhecessem como coletivo da sociedade e, com direitos a agenda da humanidade. A fonte de nossa análise foram as correspondências da marquesa reproduzidas na obra de Hernani Cidade (1930), tendo como aporte teórico, os fundamentos dos Annales.
Comparison of serum albumin level and lactate for predicting preterm morbidities and mortality
Authors: ELATAŞ Aygül , GÜLAŞI Selvi , MERT Mustafa Kurthan , KALE ÇEKİNMEZ Eren , TOLUNAY Orkun 
Published: March 2023

Purpose: We aimed to comparison of serum albumin and lactate level for predicting neonatal morbidities and mortality in preterm infants < 32 weeks of gestation.
Materials and Methods: The medical records of babies were retrospectively analyzed. Patients were divided into three groups; plasma albumin levels ≤ 2.5 g/dL were defined as Group 1, 2.6-3 g/dL as Group 2 and ≥ 3 g/dL as Group 3. The babies < 28 weeks of gestation were analysed as a subgroup.
Results: 300 infants with mean gestational age of 28.7 ± 2.4 weeks and mean birth weights 1240 ± 405 grams were included. In predicting mortality; the sensitivity of the albumin level within the first three days was 74.4% and the specificity was 73.2% (cut-off < 2.9 g/dL), the sensitivity of the lowest albumin level was 90.7% and the specificity was 70.1% (cut-off < 2.65 g/dL), the sensitivity of the lactate level was 67.4% and the specificity was 63.3% (cut off > 3.1 mmol/L). Analysis of < 28 weeks babies; the sensitivity of lowest albumin level was 80% and the specifity was 66.7% (cut-off < 2.45 g/dL) and the sensitivity of the albumin level within the first three days was 74.3% and the specificity was 72.6% (cut-off < 2.8 g/dL), and the sensitivity of lactate was 74.3% and the specifity was 64.2% (cut-off > 3.1mmol/L).
Conclusion: Low serum albumin level appears to be more specific and sensitive than lactate in predicting mortality and may be considered to be added to mortality prediction scores.
Use of methacoline challenge test to detect bronchial hyperresponsiveness in children with persistent rhinitis
Authors: USTA GÜÇ Belgin , ASİLSOY Suna 
Published: March 2023

Purpose: The incidence of persistent rhinitis in childhood is increasing day by day. Since bronchial hyperreactivity (BHR) and asthma can also be seen in a significant proportion of patients with persistent rhinitis, the use of markers that may indicate the risk of developing asthma in these patients is very important in clinical follow-up. In this study, it was aimed to demonstrate the relationship between persistent rhinitis and asthma in childhood using the bronchial methacoline challenge test (BMCT) and to investigate other factors associated with the risk of developing asthma in patients with persistent rhinitis.
Materials and Methods: Patients aged 6-18 years who presented with findings of persistent rhinitis were evaluated with a detailed history, physical examination, and spirometry. Patients with normal examination findings and spirometry findings, and patients whose examination findings and nasal inflammation findings were compatible with moderate-to-severe rhinitis were included in the study, and their atopy status was evaluated by skin prick test, and their BHR was evaluated by BMCT.
Results: Seventy-three patients were included in the study. The mean age was 9±2.7years, 45.2% of the patients were male. 63% of the patients were allergic and family history of allergy was present in 45.2% of the patients. 82.2% of the patients had BHR detected with BMCT. The median blood eosinophil count (BEC) was 320/mm3 and the IgE level was 160kU/L. Patients with atopy had statistically significantly higher IgE and BEC values compared with non-allergic patients. Patients with BHR were found to be younger, and had higher median BEC values. In multivariant analysis, it was observed that the patient's age300/mm3, and IgE levels>250IU/L increased the probability of detecting BHR with BMCT.
Conclusion: Care should be taken for every patient with persistent rhinitis because of the risk of BHR and asthma. Atopy examinations should be performed, but the possibility of developing BHR and asthma should not be overlooked even in the patients who are non- allergic.
Identification of variations in genes encoding ATP-dependent potassium channel proteins in patients with primary Raynaud's phenomenon
Authors: AKKAPULU Merih , YILDIRIM Metin , VEZİR Özden , SUCU Nehir , YALIN Ali 
Published: March 2023

Purpose: Primary Raynaud’s phenomenon (PRP) is a vascular disorder characterized by recurrent vasospastic response of the fingers and toes to cold or stress. ATP-sensitive potassium (KATP) channels are widely distributed in vasculatures, and play an important role in the vascular tone regulation. The major vascular isoform of KATP channels is composed of Kir6.1/SUR2 (KCNJ8/ABCC9). It would be important to determine whether variations of KATP genes related to PRP is thought to be associated with vasospasm. It is believed that the studies describing mechanisms involved in the pathogenesis of inherited vascular disorders offers the best opportunity for investigation of the early stages of pathogenicity and diagnosis of PRP and associated other diseases. In this study we aim to investigate possible association between genetic variations observed in KATP channel coding genes and vasospasm associated with PRP.
Materials and Methods: In our study; the cases with PRP, the relation between the variation in the KCNJ8/ABCC9 genes (S422L/V734I or rs72554071/rs61688134) was examined. 50 subjects who were diagnosed with PRP (patient group) and 50 healthy subjects (control group) were included in the study. Variations were determined using the Tetra-Primer Amplification Refractory Mutation System-Polymerase Chain Reaction (T-ARMS PCR) method.
Results: Of the individuals in the patient and control group included in the study, 21 were male and 29 were female. The mean age of the patients was 25.7±3.36 years, and the mean age of the control group was 25.9±3.44 years. No significant relationship was found between PRP disease and genotype and allele distribution of KCNJ8/ABCC9 genes.
Conclusion: This study presented the first findings about KCNJ8/ABCC9 gene variations in the Turkish population and may lead to future studies. Studies involving a higher number of cases and more mutations will be able to show whether there is a relationship between KATP channels and PRP and contribute to the elucidation of PRP pathogenesis in terms of genetic factors.
The effects of hydrogen peroxide and mitochondria on human breast cancer cells
Authors: ÇİÇEK Zehra 
Published: March 2023

Purpose: It was aimed to evaluate the effect of hydrogen peroxide (H2O2), mitochondria isolated from human breast cancer cells (MCF-7) and human mesenchymal stem cells (IMSCs) on MCF-7 cell proliferation in this study.
Materials and Methods: Mitochondria of IMSCs and MCF-7 cells were isolated according to the protocols specified in the kit and the protein amount of mitochondria was measured by the bicinchoninic acid method (BCA). H2O2 doses (0-1000 µM), mitochondria obtained from MCF-7 and IMSCs were transferred to MCF-7 cells and the viability was evaluated by tetrazolium salt (MTT) method. The cell percentages were calculated by measuring absorbance of the samples at 570 nm with a plate reader.
Results: It was found that, ATP level of the mitochondria isolated from IMSCs was higher than MCF-7s. MCF-7 cell viability decreased significantly in 30 µM (%19), 40 µM (%26), 50 µM (%39), 75 µM (%39), 100 µM (%36), 200 µM (%28), 400 µM (%23), 800 µM (%22) and 1000 µM (%23) H2O2 doses. The transfer of IMSCs mitochondria caused a tendency to decrease in cell proliferation, but no significance was detected. But, it was found that healthy mitochondria transfer with 10 µM and 1000 µM H2O2 reduced the proliferation of MCF-7s (respectively %14 and % 8).
Conclusion: It was determined that the transfer of healthy mitochondria isolated from IMSCs and H2O2 to MCF-7 is associated with proliferative processes, however transplantation of the healthy mitochondria into cancer cells is thought to be a promising new method in the treatment of the disease.