bluuebunny/crossref_metadata_2025_split huggingface dataset:
Did address influence whether gods answered prayers? Preliminary overview of Vulgar Latin names of deities in the Roman Empire
Authors: Vágási Tünde 
Published: May 2023

AbstractThis paper offers a preliminary linguistic analysis of votive texts with particular reference to their use of and variation in Latin. The aim of the linguistic analysis is to identify variation in the context of votive texts. In those votive inscriptions which contained a request, precise wording was considered crucial for the request to reach the gods. Therefore, schematic, formulaic wording is common. The epigraphic corpus under study shows various Vulgar Latin traits. The incorporation of ‘non-Roman’ or pre-Roman cults into Latin caused the greatest problems, with most variations occurring in the names of such gods. Since the names of these gods are not included in literary sources, our primary sources for these cults are inscriptions and they show characteristics of Vulgar Latin.
Social Economy 2021. Social entrepreneurship and social capital: importance-education-development
Authors: Śliwa Renata , Murzyn Dorota 
Published: May 2023

This paper reviews the conference Social Economy 2021. Social entrepreneurship and social capital: importance – education – development. The event was around the issue of social entrepreneurship and its ability to mobilize social capital and expand the labour market by including previously excluded people in its participation.
DETERMINATION OF YIELD AND QUALITY CHARACTERISTICS OF COMMON REED (Phragmites australis (Cav.) Trin. Ex Steud) HARVESTED AT DIFFERENT GROWTH STAGES
Authors: TEMEL Süleyman , KESKİN Bilal , GÜNER Zeynep , ATALAY Ali İhsan 
Published: May 2023

Common Reed (Phragmites australis (Cav.) Trin. Ex Steud, which is remained inactive and grown in saline
drainage channels, has been seen as an important potential to reduce the roughage deficit needed in animal nutrition. For this purpose, some yield, fermantation, chemical and nutritional characteristics of P.australis herbage and silage obtained from the end of the vegetative stage (EVS), the beginning of panicle (BP) and the full panicle stage (FPS) were determined. The study was carried out in 2021-2022 in Igdir, which is located in the North-East of Turkey. The results showed that the forage yield characteristics increased as the development period progressed and also that high lactic acid, low pH, acetic, propionic and butyric acid contents desired in silo feeds were obtained from the cuttings at FPS. In addition, ammonia production was low in silages at BP and FPS, but high the fleig score. It was observed that the dry matter digestibility, metabolic energy and relative feed value were higher while dry matter and crude protein ratio, acid detergent fibre and crude ash content of herbage according to silage were lower. On the other hand, the desired chemical and nutritional values in both herbage and silage were determined during the most suitable BP. As a result, it was determined that the common reed was appropriate to harvest in FPS for a silo feed with high yield and fermentation properties. In addition, it was concluded that the herbage and silage harvested at BP produced a higher quality feed material in terms of nutritional and chemical composition, respectively.
Study of low amniotic fluid index and its effect on perinatal outcome
Authors: Kumari Nisha , Tiwari Nisha 
Published: May 2023

AFI may be an important predictor for deciding timing of delivery and adverse maternal and fetal outcome. Hence, we aimed at determining whether an antepartum low amniotic fluid index (AFI) is a predictor of adverse perinatal outcome in normal pregnancy and to determine a threshold level of AFI that could predict an adverse outcome. This study was conducted as an observational study on a total of 100 antenatal females presenting with term pregnancy at Department of Obstetrics and Gynecology, Lord Mahavir Civil Hospital, Ludhiana during study period. Detailed history and clinical examination was done. AFI was assessed with help of USG. The study was conducted on a total of 100 antenatal females. AFI was &#60;5 in 38%. Low AFI was associated with LSCS and negative fern test was statistically significant (p&#60;0.05). We observed a significant association of low AFI with low birth weight, poor APGAR score at 1 as well as 5 minutes and higher risk of NICU admission (p&#60;0.05). The area under the curve and sensitivity as well as specificity at cutoff (4.5) was maximum for NICU admission followed by LSCS (p&#60;0.05). AFI is an important determinant of adverse maternal and fetal outcome. AFI &#60;5 is associated with adverse maternal outcome in the form of higher operative delivery and adverse fetal outcome i.e. low birth weight, meconium stained liquor, low APGAR score and higher NICU admission. Intensive intrapartum care along with fetal surveillance may help in minimizing adverse perinatal outcomes.
Analysis of factors increasing the risk of prelabour rupture of membranes and its effect on fetomaternal outcome
Authors: Tiwari Shraddha , Mishra Nitu , Kumar Aruna 
Published: May 2023

Perinatal morbidity and mortality due to prelabour rupture of membranesPROM) is 18-20% and 21.4% respectively. Multiple risk factors are associated with the development of PROM. Limited data is available on the risk factors of term PROM and relation of its duration with adverse maternal and fetal outcomes from India. To assessfactors increasing the risk of PROM and effect of duration of rupture of membranes on fetomaternal outcome. Five hundred and ten patients presented with term PROM in the Department of Obstetrics and Gynaecology, Sultania Zanana Hospital, Gandhi Medical College, Bhopal, Madhya Pradesh (M.P.) from December 2018 to February 2019 were studied. After the detailed history, sociodemographic details, risk factors for PROM and neonatal outcomes were recorded. PROM was more common in women with age 21-25years (73.3%), who were housewife (92.5%), were underweight (21.37%), were from the rural area (58.4%), belong to lower SES (62.8%) and were primigravida (59.2%). Majority were leaking for 13-24 hours (70.2%). Majority (85.64%) of patients had spontaneous onset of labour in less than 24 hours of PROM and 28(14.35%) went into spontaneous labour after 24 hours of PROM. Most common risk factor was malpresentation (46.52%) followed by history of PROM (30.04%), Polyhydramnios (13.19%), multiple pregnancy (10.99%) and febrile illness (6.96%). Out of 312 women who had vaginal delivery, labour was induced in 87.82% women. The most common indication for Caesarean section was previous 1 LSCS (13.1%), followed by fetal distress (8.6%), breech presentation (7.3%) and cephalopelvic disproportion (2.9%). Most of the women presenting with PROM were delivered vaginally (61.2%), while 38.8% women underwent caesarean section. Out of 529 babies, 6.24% were admitted in NICU. Majority of the neonates were admitted for 3 days (39.39%). PROM is associated with poor fetomaternal outcome and timely diagnosis and prompt management is required for better outcome.
A randomised double blind clinical study on effect between clomiphene citrate plus metformin and clomiphene citrate alone on induction of ovulation in women with polycystic ovarian syndrome
Authors: Chakraborty Anwesha , Dwibedi Debasmita , Das Chandana , Ghosh Debnath 
Published: May 2023

Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder of women of reproductive age-group, characterised by a combination of hyperandrogenism, chronic anovulation, and polycystic ovaries. It is one of the most common cause of hyperandrogenism, hirsutism and anovulatory infertility. The aim of the study is to determine & compare the rate of ovulation, regularisation of menstrual cycle and rate of pregnancy by use of combination of Clomiphene citrate and Metformin & with use of Clomiphene citrate alone in patients with PCOS.A total 110 patients (55 in each group) having primary subfertility and diagnosed as PCOS in age group of 18 to 40 years of age, selected between April 2017 – March 2018. The primary outcome i.e, incidence of ovulation was detected by folliculometry. The secondary outcomes, i.e, regularisation of menstrual cycle & Pregnancy rates were taken into account and compared in both the groups.Overall ovulation was found highest at the end of 3rd cycle of ovulation induction, 48.8% and 41% respectively in each group. The Primary outcome was significantly higher in group a given combination of clomiphene citrate and metformin (83.3%) with respect to group B given clomiphene citrate only (65.9%). The secondary outcomes were significantly higher in group given CC plus metformin (89.6%). Pregnancy rates were higher in 1st group 33.3% than 2nd group (20.5%).In the present study one group was given combination of Clomiphene citrate with metformin and another group was given clomiphene citrate only for ovulation induction. It was found that combination of clomiphene citrate and metformin was more effective in induction of ovulation in women suffering from PCOS when compared to induction of ovulation with clomiphene citrate alone.
A case of missed mixed germ cell tumor of ovary in pregnancy
Authors: Pais Janice A , Fernandes Venita Roshal , Rao Sujaya V 
Published: May 2023

Ovarian germ cell tumor accounts for 18-26% of all ovarian cancers complicating pregnancy. This is a rare case of mixed germ cell tumor of ovary, misdiagnosed antenatally as uterine fibroid. A 34-year-old primigravida at 37 weeks + 5 days POG came in latent labor. Term scan showed fibroid of 11x 9cms in posterior wall in lower uterine segment with central cystic area. She underwent emergency LSCS and delivered a male baby weighing 2.005 kg. On exteriorization of uterus, a 10 x 8 cm necrotic mass was present posterior to uterus in rectovaginal space measuring 10 x 8 cm. It was concluded as FIGO Stage IC1 ovarian carcinoma.Histopathology of the mass showed mixed germ cell tumor: 60% yolk sac tumor and 40% dysgerminoma. MRI done after 2 weeks showed a lesion of 10.4 x 9.5 x 7.3 cm in rectovaginal pouch compressing and displacing the rectum posteriorly and to the left side, also displacing uterus and bladder anteriorly, Left ovary normal, Right ovary not visualized. Hence, she received 4 cycles of chemo comprising cisplatin and etoposide.After chemo, PET scan showed a lesion of 6.7x 6.2 x 4.2 cm in the rectovaginal area just right to the midline with right ovary not being visualized separately. Hence, she underwent laparoscopic right oophorectomy. Histopathology showed extensive regressive changes with occasional scattered atypical cells with no conclusive evidence of residual tumor. Follow up serum LDH and AFP are within normal limits and advised to follow up once in 3 months to look for any recurrences. : Any mass during pregnancy even if found to be benign, should be further evaluated and monitored regularly to reduce the morbidity /mortality to the mother.
Primary Nodal Merkel Cell Carcinoma: Rare Presentation
Authors: TEKİN Emel , ÖZEN Alaattin , GÜRBÜZ Melek 
Published: May 2023

Merkel cell carcinoma (MCC) is a very rare high-grade neuroendocrine carcinoma that is frequently located in the skin. Although most cases are associated with Merkel cell polyomavirus, there are also cases in which the virus cannot be detected. The purpose of presenting the case of MCC with primary nodal involvement is due to its rare presentation.
A 59-year-old male patient presented to the hospital with painless mass in the neck. Imaging analyses revealed necrotic lymphadenopathies on the neck, measuring up to 4.5 cm in size. After an explorative surgery with preliminary diagnoses of lymphoma and squamous cell carcinoma , samples taken from the excised mass showed high-grade neuroendocrine carcinoma morphology. In addition to neuroendocrine markers, CK7 and CK20 positivity were observed in the immunohistochemical tests performed. As a result, the case was evaluated in favor of MCC with negativity of markers performed to exclude other malignancies. Subsequently, a diagnosis of primary nodal MCC was made due to the absence of a different focus other than lymph node on PET imaging analysis.
The differential diagnosis should be kept broad due to the histopathological morphology of small round cell malignant tumors. In addition in high-grade neuroendocrine carcinomas, the possibility of MCC should be ruled out especially if CK20 positivity is present. Although is has been reported that primary nodal MCC cases have a better clinical course compared to nodal metastatic cases with a known primary, there are limited case series studies on this topic. A multisystem approach is recommended for proper clinical management.
Achalasia Post-Bariatric Surgery, Placement Roux-en-Y Gastric Bypass. Case Report
Authors: Landeros-Ruiz Juan Pablo , Zúñiga-Ramos Lourdes Marlene , Cárdenas-Guerrero Daniela , Torres Quitzia Libertad 
Published: May 2023

INTRODUCTION: Achalasia is a pathology with an incidence of 1 in 100,000 inhabitants per year. There are very limited data on achalasia in the obese population, especially in those undergoing bariatric surgery. The approach of choice for cases of achalasia is fundoplication to correct the reflux; however, lacking a fundus due to a previous gastrectomy, an alternative that offers optimal results should be chosen. Here we present the surgical approach in a case of esophageal achalasia and a history of vertical sleeve gastrectomy, where we performed simultaneous Heller&#039;s cardiomyotomy and laparoscopic Roux-en-Y gastric bypass, as well as the results obtained.
CASE PRESENTATION: 44-year-old woman with no chronic degenerative diseases, with a previous record of vertical sleeve gastrectomy 5 years ago, who started 1 year and 5 months earlier with dysphagia to liquids, then to solids, in addition to weight loss of 10 kilograms in 4 months. The BMI before vertical sleeve gastrectomy was 32 kg/m2, her BMI at the time of admission was 20 kg/m2; she also presented regurgitation and generalized weakness. After analyzing the surgical options, it was decided to perform a Heller cardiomyotomy and a Roux-en-Y gastric bypass.
DISCUSSION AND CONCLUSIONS: The procedure turned out to be safe and successful in treating achalasia symptomatology, in addition to complete resolution of the reflux symptom.
Special Connections for Representing Multiscale Heterogeneities in Reservoir Simulation
Authors: Correia Manuel Gomes , Oliveira Gonçalo , Schiozer Denis José 
Published: May 2023

Summary
The significant quantities of oil contained in fractured karst reservoirs in Brazilian presalt fields add new challenges to the development of upscaling procedures to reduce time on numerical simulations. This work aims to represent multiscale heterogeneities in reservoir simulators based on special connections between matrix, karst, and fracture mediums, both modeled in different grid domains within a single porosity flow model. The objective of this representation is to strike a good balance between accuracy and simulation time. Therefore, this work extends the approach of special connections developed by Correia et al. (2019) to integrate both karst and fracture mediums modeled in different grid domains and block scales. The transmissibility calculation between the three domains is a combination of the conventional formulation based on two-point flux approximation schemes and the matrix-fracture fluid transfer formulation. The flow inside each domain is governed by Darcy’s equation and implicitly solved by the simulator. For proper validation and numerical verification, we applied the methodology to a simple case (two-phase and three-phase flow) and a real case (two-phase flow). For the simple case, the reference model is a refined grid model with (1) an arrangement of large conduits (karsts), which are poorly connected; (2) a well-connected and orthogonal system of fractures; and (3) a background medium (matrix). The real case is a section of a Brazilian presalt field, characterized as a naturally fractured carbonate reservoir. The reference is the geological model. The simulation model consists of a structural model with different gridblock sizes according to the scale of the heterogeneities—small-scale karst geometries, medium-scale matrix properties, and larger-scale fracture features—interconnected by special connections. The results for both cases show a significant performance improvement regarding a dynamic matching response with the reference model, within a suitable simulation time and maintaining the dynamic resolution according to the representative elementary volume of heterogeneities, without using an unstructured grid. In comparison to the reference model, for the simple case and the real case, the simulation time was reduced by 42% and 87%, respectively. The proposed method contributes to a multiscale flow simulation solution to manage heterogeneous geological scenarios using structured grids while preserving the high resolution of small-scale heterogeneities and providing a good relationship between accuracy and simulation time.
Physics-Guided Deep Learning for Improved Production Forecasting in Unconventional Reservoirs
Authors: Mohd Razak Syamil , Cornelio Jodel , Cho Young , Liu Hui-Hai , Vaidya Ravimadhav , Jafarpour Behnam 
Published: May 2023

Summary
The complexity of physics-based modeling of fluid flow in hydraulically fractured unconventional reservoirs, together with the abundant data from repeated factory-style drilling and completion of these resources, has prompted the development and application of data-driven statistical models for predicting hydrocarbon production performance. More recently, machine learning algorithms have been widely studied in developing data-driven prediction models for unconventional reservoirs. These models often require a large amount of high-quality training data with sufficient range to avoid excessive extrapolation and produce reliable predictions. Unlike statistical models, physics-based models represent causal relations between input and output variables to provide predictions beyond available data. While a detailed physics-based description of fluid flow in unconventional reservoirs is not yet available, approximate physical flow functions have been proposed to capture the general production behavior of unconventional wells. These physical functions can be augmented with the available data to improve data-driven methods by constraining the models to adhere to the general production trends. In this paper, we develop a physics-constrained data-driven model by embedding physical flow functions into neural network models. Since the performance of the physics-constrained model depends on the relevance of the embedded physics, a sizeable residual prediction error is expected if the collected data do not sufficiently match the embedded model. The residual model typically represents errors in the description of inputs or any missing physical phenomenon. We compensate for such errors through residual learning, where an auxiliary neural network is designed to learn the complex relationship between the input parameters (such as formation and completion properties) and the expected prediction residuals. The new physics-guided deep learning (PGDL) model augments any physics-constrained prediction model with residual learning to increase its prediction accuracy. Several synthetic and actual field data sets, from the Bakken play, are used to demonstrate the performance of the PGDL model.
Care intervention on psychological outcomes among patients admitted to intensive care unit: an umbrella review of systematic reviews and meta-analyses
Authors: Zheng Yafang , Zhang Lijuan , Ma Shihong , Wu Bian , Chen Peipei , Xu Yan , Tan Wenting , Li Hanzhan , Wu Qiaomei , Zheng Jingxia 
Published: May 2023

Abstract
Background
Numerous studies have explored care interventions to improve the psychological outcome of intensive care unit (ICU) patients, but inconclusive evidence makes it difficult for decision-makers, managers and clinicians to get familiar with all available literatures and find appropriate interventions. This umbrella review aimed to analyze the relationship between care intervention and psychological outcomes of ICU patients bases on existing systematic reviews.
Methods
Umbrella review of evidence across systematic reviews and meta-analyses published between 1987 and 2020 was undertaken. We systematically searched primary studies that examined the association between care intervention and the improvement of adverse psychological outcomes in ICU patients using PubMed, EMBASE, web of science, Cochrane library, and manual reference screening. The measurement tool (AMSTAR 2) was applied to evaluate the methodological quality of included studies. The excess significance bias, between-study heterogeneity expressed by I2, small study effect and evidence class were estimated.
Results
A total of 5110 articles were initially identified from the search databases and nine of them were included in analysis. By applying standardized criteria, only week evidence was observed in 13 associations, even though most included reviews were of moderate to high methodological quality. These associations pertained to eight interventions (music therapy, early rehabilitation, post ICU follow up, ICU diary, information intervention, preoperative education, communication and psychological support, surrogate decision-making) and five psychological outcomes (post intensive care syndrome, transfer anxiety, post-traumatic stress disorder, anxiety and depression). Weak or null association was shown among the rest of the associations (e.g., weak association between music therapy and maternal anxiety or stress level).
Conclusions
The evidence of these eight supporting interventions to improve the adverse psychological outcomes of ICU patients and caregivers was weak. Data from more and better-designed studies with lager sample size are needed to establish robust evidence.
RUNX1/ETO Regulates Reactive Oxygen Species (ROS) Levels in t(8,21) Acute Myeloid Leukaemia via FLT3 and RAC1
Authors: Azlan Adam , Khor Kang Zi , Rajasegaran Yaashini , Rosli Aliaa Arina , Said Mohamed Saifulaman Mohamed , Yusoff Narazah Mohd , Moses Emmanuel Jairaj 
Published: May 2023

Abstract
Reactive oxygen species (ROS) homeostasis is crucial for leukaemogenesis. and deregulation would hamper leukaemic progression. Although the regulatory effects of RUNX1/ETO has been extensively studied, its underlying molecular mechanims in ROS production in t(8,21) AML is yet to be fully elucidated. Here, we report that RUNX1/ETO could directly control FLT3 by occupying several DNA elements on FLT3 locus. The possible hijacking mechanism by RUNX1/ETO over FLT3 mediated ROS modulation in AML t(8;21) was made apparent when suppression of RUNX1/ETO led to decrement in ROS levels and the direct oxidative marker FOXO3 but not in FLT3 and RAC1 suppressed t(8,21) AML cell line Furthermore, nuclear import of RUNX1/ETO was aberrated following RUNX1/ETO and RAC1 suppression suggesting association in ROS control. A different picture was depicted in non t(8;21) cells where suppression of RAC1 and FLT3 led to decreased levels of FOXO3a and ROS. Results alltogether indicate a possible dysregulation of ROS levels by RUNX1/ETO on t(8,21) AML.