bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors associated with blue-collar workers’ participation in Worksite Health Promotion Programs: a scoping literature review
Authors: Damen Marc A W , Detaille Sarah I , Robroek Suzan J W , Engels Josephine A , de Lange Annet H 
Published: June 2023

Abstract
A growing number of employers implement worksite health promotion programs (WHPPs). In particular, blue-collar workers may benefit from these WHPPs. However, they are less likely than other workers to participate and little is known about which factors affect their participation. The aim of this scoping literature review is to produce an overview of studies on factors associated with blue-collar workers’ participation in WHPPs. Five databases were searched: BSU, PsycINFO, Medline, Web of Science and CINAHL. The review included peer-reviewed empirical studies on determinants associated with blue-collar workers’ participation in WHPPs. Factors were extracted and categorized. Similar determinants were clustered and the direction of the associations was further examined. Nineteen papers describing 11 qualitative and 4 quantitative studies met the eligibility criteria. Seventy-seven determinants were analyzed (in quantitative studies) or reported (in qualitative studies). In most studies, only participant characteristics were investigated. Participation may be enhanced by addressing needs, tailoring from a broad range of activities, offering group activities, requiring little effort and commitment at the start, using incentives, leading by example and combining WHPPs with occupational safety interventions. WHPPs seem to be able to reach blue-collar workers, but it remains particularly challenging to reach shift workers and those who do not yet experience health complaints.
NGLY1 deficiency: a prospective natural history study
Authors: Tong Sandra , Ventola Pamela , Frater Christina H , Klotz Jenna , Phillips Jennifer M , Muppidi Srikanth , Dwight Selina S , Mueller William F , Beahm Brendan J , Wilsey Matt , Lee Kevin J 
Published: June 2023

Abstract
N-glycanase 1 (NGLY1) deficiency is a debilitating, ultra-rare autosomal recessive disorder caused by loss of function of NGLY1, a cytosolic enzyme that deglycosylates other proteins. It is characterized by severe global developmental delay and/or intellectual disability, hyperkinetic movement disorder, transient elevation of transaminases, (hypo)alacrima and progressive, diffuse, length-dependent sensorimotor polyneuropathy. A prospective natural history study (NHS) was conducted to elucidate clinical features and disease course. Twenty-nine participants were enrolled (15 onsite, 14 remotely) and followed for up to 32 months, representing ~29% of the ~100 patients identified worldwide. Participants exhibited profound developmental delays, with almost all developmental quotients below 20 on the Mullen Scales of Early Learning, well below the normative score of 100. Increased difficulties with sitting and standing suggested decline in motor function over time. Most patients presented with (hypo)alacrima and reduced sweat response. Pediatric quality of life was poor except for emotional function. Language/communication and motor skill problems including hand use were reported by caregivers as the most bothersome symptoms. Levels of the substrate biomarker, GlcNAc-Asn (aspartylglucosamine; GNA), were consistently elevated in all participants over time, independent of age. Liver enzymes were elevated for some participants but improved especially in younger patients and did not reach levels indicating severe liver disease. Three participants died during the study period. Data from this NHS informs selection of endpoints and assessments for future clinical trials for NGLY1 deficiency interventions. Potential endpoints include GNA biomarker levels, neurocognitive assessments, autonomic and motor function (particularly hand use), (hypo)alacrima and quality of life.
Archetypes of product launch by insiders, outsiders, and visionaries
Authors: Greenstein Shane 
Published: June 2023

Abstract
What archetypes emerge from prominent episodes of product launches? This essay examines a set of episodes in information technology history that led to significant changes in industry leadership. It highlights that, in all of these instances, there is an example of a “visionary” archetype—an individual or a set of leaders who promulgate a unique view for addressing a business opportunity, which they use as they launch a new product. These archetypes are couched as insiders or outsiders depending on the firm’s status before the new product launch, and incumbent market leaders are insiders. The narrative arc is similar, as the visionary first encounters resistance and crises, must overcome challenges, and usually has to overcome skeptics via a product launch that gains market acceptance. However, the narratives of insiders and outsiders differ systematically based on their market position, leading to asymmetric approaches to market competition. This review stresses the importance of visionaries in industrial change brought about by product entry. It raises questions about integrating such narratives into the analysis of significant changes in market structure.
The Regulation of Pre-election Polls: A Citizen’s Perspective
Authors: Daoust Jean-François , Mongrain Philippe 
Published: June 2023

Abstract
The number of legislations around the world restricting the use and publication of pre-election polls during election campaigns is on the rise. However, we do not have a good sense of the extent to which citizens are against the publication of pre-election polls and what factors drive support or opposition for their regulation. In this research note, we tackle these issues using data from the 2019 Canadian Election Study. Our findings show that citizens are quite divided on whether polls should be banned during the last week of the campaign. Moreover, contrary to our expectations, we find almost no evidence of partisan effects in citizens’ opinions about the regulation of polls. We interpret these findings as good news for democracy as citizens, at least in some contexts, do not seem to rely on partisan considerations when it comes to the regulation of political information.
Technological diversification of U.S. cities during the great historical crises
Authors: Steijn Mathieu P A , Balland Pierre-Alexandre , Boschma Ron , Rigby David L 
Published: June 2023

Abstract
Regional resilience is high on the scientific and policy agenda. An essential feature of resilience is diversifying into new activities but little is known about whether major economic crises accelerate or decelerate regional diversification. This article shows how crises impact the development of new technological capabilities within U.S. metropolitan areas by examining three of the largest downturns in U.S. history, the Long Depression (1873–1879), the Great Depression (1929–1934) and the 1970s recession (1973–1975). We find that crises (i) reduce the pace of diversification in cities and (ii) narrow the scope of diversification to more closely related activities. This pattern seems general as it also holds for smaller, local crises. Evidence is presented that this general pattern of technological diversification strongly hampers employment growth. Additionally, we find that diverse cities generally diversify more strongly during times of crisis.
Risk factors for the development of second primary esophageal squamous-cell carcinoma after endoscopic resection for esophageal squamous-cell carcinoma according to genetic polymorphisms related to alcohol and nicotine metabolism
Authors: Katada Chikatoshi , Yokoyama Tetsuji , Mure Kanae , Doyama Hisashi , Nakanishi Hiroyoshi , Shimizu Yuichi , Yamamoto Keiko , Furue Yasuaki , Tamaoki Masashi , Koike Tomoyuki , Kawahara Yoshiro , Kiyokawa Hirofumi , Konno Maki , Yokoyama Akira , Ohashi Shinya , Ishikawa Hideki , Yokoyama Akira , Muto Manabu 
Published: June 2023

Abstract

Background
Multiple development of esophageal squamous-cell carcinoma is explained by field cancerization and is associated with alcohol consumption and smoking. We investigated the association between the development of second primary esophageal squamous-cell carcinoma after endoscopic resection for esophageal squamous-cell carcinoma and genetic polymorphisms related to alcohol and nicotine metabolism.

Methods
The study group comprised 56 patients with esophageal squamous-cell carcinoma after endoscopic resection. The main variables were the following: (i) cumulative incidence and total number of second primary esophageal squamous-cell carcinoma according to genetic polymorphisms in alcohol dehydrogenase 1B, aldehyde dehydrogenase 2 and cytochrome P450 2A6; and (ii) risk factors of second primary esophageal squamous-cell carcinoma identified using a multivariate Cox proportional-hazards model. The frequencies of alcohol dehydrogenase 1B, aldehyde dehydrogenase 2 and cytochrome P450 2A6 genetic polymorphisms in the buccal mucosa were analyzed.

Results
The median follow-up was 92.8 months (range: 2.7–134.2). Slow-metabolizing alcohol dehydrogenase 1B was associated with a higher 7-year cumulative incidence of second primary esophageal squamous-cell carcinoma (fast-metabolizing alcohol dehydrogenase 1B vs slow-metabolizing alcohol dehydrogenase 1B: 20.5% vs 71.4%, P = 0.006). Slow-metabolizing alcohol dehydrogenase 1B (relative risk [95% confidence interval]: 3.17 [1.49–6.73]), inactive aldehyde dehydrogenase 2 (2.17 [1.01–4.63]) and poorly-metabolizing cytochrome P450 2A6 (4.63 [1.74–12.33]) had a significantly higher total number of second primary esophageal squamous-cell carcinoma per 100 person-years. In the multivariate Cox proportional-hazards model, slow-metabolizing alcohol dehydrogenase 1B was a significant risk factor of the development of second primary esophageal squamous-cell carcinoma (hazard ratio 9.92, 95% confidence interval: 2.35–41.98, P = 0.0018).

Conclusions
Slow-metabolizing alcohol dehydrogenase 1B may be a significant risk factor for the development of second primary esophageal squamous-cell carcinoma. In addition, inactive aldehyde dehydrogenase 2 and poorly-metabolizing cytochrome P450 2A6 may be important factors.
A risk scoring system for early diagnosis of anastomotic leakage after subtotal esophagectomy for esophageal cancer
Authors: Sugita Shizuki , Miyata Kazushi , Shimizu Daisuke , Ebata Tomoki , Yokoyama Yukihiro 
Published: June 2023

Abstract

Background
Anastomotic leakage (AL) is one of the most critical postoperative complications after subtotal esophagectomy in patients with esophageal cancer. This study attempted to develop an optimal scoring system for stratifying the risk for AL.

Methods
The study included 171 patients who underwent subtotal esophagectomy for esophageal cancer followed by esophagogastrostomy in the cervical region from January 2011 to April 2021 at Nagoya University Hospital. AL was defined by radiologic or endoscopic evidence of anastomotic breakdown using some modalities. A risk scoring system for an early diagnosis of AL was established using factors determined in the multivariate analysis. A score was calculated for each patient, and the patients were classified into three categories according to the risk for AL: low-, intermediate- and high-risk. The trend of the risk for AL among the categories was evaluated.

Results
Twenty-nine patients (17%) developed AL. Multivariate analysis demonstrated that sinistrous gross features of drain fluid (P &lt; 0.001; odds ratio (OR), 10.2), radiologic air bubble sign (P &lt; 0.001; OR, 15.0) and the level of drain amylase ≥280 U/L on postoperative Day 7 (P &lt; 0.001; OR, 9.0) were significantly associated with AL. According to the matching number of the above three risk factors and categorization into three risk groups, the incidence of AL was 6.1% (8/131) in the low-risk group, 45.5% (15/33) in the intermediate-risk group and 85.7% (6/7) in the high-risk group (area under curve, 0.81; 95% confidence interval, 0.72–0.90).

Conclusions
The present AL-risk scoring system may be useful in postoperative patient care after subtotal esophagectomy.
Decreasing incidence of conjunctival squamous cell carcinoma in people with HIV in South Africa
Authors: Metekoua Carole , Ruffieux Yann , Olago Victor , Dhokotera Tafadzwa , Egger Matthias , Bohlius Julia , Rohner Eliane , Muchengeti Mazvita 
Published: June 2023

Abstract

Background
The main risk factors for squamous cell carcinoma of the conjunctiva (SCCC) are immunodeficiency and exposure to ultraviolet radiation. Little is known about SCCC epidemiology among people with HIV (PWH) in South Africa.

Methods
We used data from the South African HIV Cancer Match study, a nation-wide cohort of PWH in South Africa, created through a privacy-preserving probabilistic record linkage of HIV-related laboratory records from the National Health Laboratory Service and cancer records from the National Cancer Registry from 2004 to 2014. We calculated crude incidence rates, analyzed trends using joinpoint models, and estimated hazard ratios for different risk factors using Royston-Parmar flexible parametric survival models.

Results
Among 5 247 968 PWH, 1059 cases of incident SCCC were diagnosed, for a crude overall SCCC incidence rate of 6.8 per 100 000 person-years. The SCCC incidence rate decreased between 2004 and 2014, with an annual percentage change of ‒10.9% (95% confidence interval: ‒13.3 to ‒8.3). PWH residing within latitudes 30°S to 34°S had a 49% lower SCCC risk than those residing at less than 25°S latitude (adjusted hazard ratio = 0.67; 95% confidence interval: 0.55 to 0.82). Other risk factors for SCCC were lower CD4 counts and middle age. There was no evidence for an association of sex or settlement type with SCCC risk.

Conclusions
An increased risk of developing SCCC was associated with lower CD4 counts and residence closer to the equator, indicative of higher ultraviolet radiation exposure. Clinicians and PWH should be educated on known SCCC preventive measures, such as maintaining high CD4 counts and protection from ultraviolet radiation through sunglasses and sunhats when outdoors.
Parental Communication About Body Weight and Adolescent Health: The Role of Positive and Negative Weight-Related Comments
Authors: Lessard Leah M , Puhl Rebecca M , Foster Gary D , Cardel Michelle I 
Published: June 2023

Abstract

Objective
Research has consistently documented adverse effects of parent weight-related comments on adolescent health. However, little empirical attention has focused on isolating the impact of weight-related comments from mothers versus fathers, and the valence of their comments. The present study examined the extent to which positive and negative weight-related comments from mothers and fathers are related to adolescent health and wellbeing, and whether these associations differ according to adolescent sociodemographic characteristics.

Methods
Data were collected from a diverse sample of 2032 U.S.-based adolescents aged 10–17 years (59% female; 40% White, 25% Black or African American, 23% Latinx). Online questionnaires assessed perceived frequency of negative and positive weight-related comments from mothers and fathers, as well as four indicators of adolescent health and wellbeing: depression, unhealthy weight control behaviors, weight bias internalization (WBI), and body appreciation.

Results
More frequent negative weight-related comments from parents were associated with poorer adolescent health and wellbeing, while positive comments contributed to lower levels of WBI and body appreciation; these associations were documented regardless of whether mothers or fathers were the source of such comments, and considerable consistency was demonstrated across adolescent sociodemographic characteristics.

Conclusion
Findings highlight differences in adolescent health based on how parents discuss their body weight (i.e., negatively or positively), and similarity in associations regardless of whether mothers or fathers are the source of weight communication. These findings reiterate the importance of efforts to educate parents on ways to engage in supportive communication about weight-related health with their children.
Energy planning for integrating renewable energy: A dilemma of utilizing ultra-high voltage transmission systems in China
Authors: Dai Anni 
Published: June 2023

Abstract
To enable the transition to clean energy and mitigate climate change, China has developed an extensive ultra-high voltage (UHV) transmission network for renewable energy integration. Nevertheless, this network is not being utilized to its full potential, indicating the importance of coordinated energy planning. This article examines the disputes over the Yazhong-to-Jiangxi UHV projects and identifies institutional constraints rooted in the regulatory structure, which hinder the effective utilization of the UHV networks under China’s Electricity Law. These constraints include deficiencies in the energy planning framework, inconsistencies in transmission planning authority, non-binding approval system and gaps in relevant laws. This article concludes with recommendations for reforming the transmission planning and approval system, improving regulatory capacity and amending energy laws to optimize the role of UHV transmission systems in renewable energy integration.
From the lab to the field: CRISPR/Cas addressing challenges in agriculture
Authors: Giordano Andrea 
Published: June 2023

This article comments on:
Tang Y, Zhang Z, Yang Z, Wu J. 2023. CRISPR/Cas9 and Agrobacterium tumefaciens virulence proteins synergistically increase efficiency of precise genome editing via homology-directed repair in plants. Journal of Experimental Botany 74, 3518–3530.
First light and reionization epoch simulations (Flares) X: environmental galaxy bias and survey variance at high redshift
Authors: Thomas Peter A , Lovell Christopher C , Maltz Maxwell G A , Vijayan Aswin P , Wilkins Stephen M , Irodotou Dimitrios , Roper William J , Seeyave Louise 
Published: June 2023

ABSTRACT
Upcoming deep galaxy surveys with JWST will probe galaxy evolution during the epoch of reionization (EoR, 5 ≤ z ≤ 10) over relatively compact areas (e.g. ∼300 arcmin2 for the JADES GTO survey). It is therefore imperative that we understand the degree of survey variance to evaluate how representative the galaxy populations in these studies will be. We use the First Light And Reionization Epoch Simulations (Flares) to measure the galaxy bias of various tracers over an unprecedentedly large range in overdensity for a hydrodynamic simulation, and use these relations to assess the impact of bias and clustering on survey variance in the EoR. Star formation is highly biased relative to the underlying dark matter distribution, with the mean ratio of the stellar to dark matter density varying by a factor of 100 between regions of low and high matter overdensity (smoothed on a scale of 14 h−1 cMpc). This is reflected in the galaxy distribution – the most massive galaxies are found solely in regions of high overdensity. As a consequence of the above, galaxies in the EoR are highly clustered, which can lead to a large variance in survey number counts. For mean number counts N ≲ 100 (1000), in a unit redshift slice of angular area 300 arcmin2 (1.4 deg2), the 2σ range in N is roughly a factor of four (two). We present relations between the expected variance and survey area for different survey geometries; these relations will be of use to observers wishing to understand the impact of survey variance on their results.
A local universe model for constrained simulations
Authors: Pfeifer Simon , Valade Aurélien , Gottlöber Stefan , Hoffman Yehuda , Libeskind Noam I , Hellwing Wojciech A 
Published: June 2023

ABSTRACT
The aim of cosmological simulations is to reproduce the properties of the observed Universe, serving as tools to test structure and galaxy formation models. Constrained simulations of our local cosmological region up to a few hundred $h^{-1}\, \mbox{Mpc}$ , the Local Universe, are designed to reproduce the actual cosmic web of structures as observed. A question that often arises is how to judge the quality of constrained simulations against the observations of the Local Universe. Here we introduce the Local Universe model (LUM), a new methodology, whereby many constrained simulations can be judged and the ‘best’ initial conditions can be identified. By characterizing the Local Universe as a set of rich clusters, the model identifies haloes that serve as simulated counterparts to the observed clusters. Their merit is determined against a null hypothesis, the probability that such a counterpart could be identified in a random, unconstrained simulation. This model is applied to 100 constrained simulations using the Cosmicflows-3 data. Cluster counterparts are found for all constrained simulations, their distribution of separation from the true observed cluster position and their mass distribution are investigated. Lastly, the ‘best’ constrained simulation is selected using the LUM and discussed in more detail.
Mapping non-axisymmetric velocity fields of external galaxies
Authors: Sylos Labini Francesco , Straccamore Matteo , De Marzo Giordano , Comerón Sébastien 
Published: June 2023

ABSTRACT
Disc galaxies are typically in a stable configuration where matter moves in almost closed circular orbits. However, non-circular motions caused by distortions, warps, lopsidedness, or satellite interactions are common and leave distinct signatures on galaxy velocity maps. We develop an algorithm that uses an ordinary least squares method for fitting a non-axisymmetric model to the observed two-dimensional line-of-sight velocity map of an external galaxy, which allows for anisotropic non-circular motions. The method approximates a galaxy as a flat disc, which is an appropriate assumption for spiral galaxies within the optical radius where warps are rare. In the outer parts of H i distributions, which may extend well into the warp region, we use this method in combination with a standard rotating tilted ring model to constrain the range of radii where the flat disc assumption can be conservatively considered valid. Within this range, the transversal and radial velocity profiles, averaged in rings, can be directly reconstructed from the velocity map. The novelty of the algorithm consists in using arc segments in addition to rings; in this way, spatial velocity anisotropies can be measured in both components, allowing for the reconstruction of angularly resolved coarse-grained two-dimensional velocity maps. We applied this algorithm to 25 disc galaxies from the THINGS sample, for which we can provide 2D maps of both velocity components.