bluuebunny/crossref_metadata_2025_split huggingface dataset:
High‐Efficiency Charge Injection with Discharge Mitigation Strategy for Triboelectric Dielectric Materials
Authors: Zhao Qionghua , Wu Huiyuan , Wang Jian , Xu Shuyan , He Wencong , Shan Chuncai , Fu Shaoke , Li Gui , Li Kaixian , Hu Chenguo 
Published: August 2023

AbstractThe high surface charge density of triboelectric dielectric materials is the core of high output performance triboelectric nanogenerators (TENGs). However, the increase in surface charge density enabled by the existing triboelectric material modification is still far from the saturation value (σBS) limited by air breakdown. Here, utilizing the directional high electric field generated by the charge excitation technology of the voltage‐multiplying circuit, an ultrafast charge self‐injection strategy is proposed. An ordinary contact‐separation TENG with a working frequency of 1.5 Hz can realize charge self‐injection on the surface of its dielectric layer to a saturation value within 22 s. Furthermore, the surface charge on the dielectric layer after excessive charge self‐injection can be retained to the maximum value by the step‐by‐step discharge mitigation strategy. Finally, by using a 7 µm thick polyimide film, a super‐high charge density of 1480 µC m−2 is achieved after charge injection, which is the historical high by modification of single layer material series currently. The charge self‐injection technology combined with discharge mitigation strategy proposed in this work is an important breakthrough in the field of triboelectric layer modification. In addition, this work also provides a systematic discussion on the σBS of dielectric layer related physical mechanism.
Internal and External Cultivation Design of Zero‐Strain Columbite‐Structured MNb2O6 toward Lithium‐Ion Capacitors as Competitive Anodes
Authors: Cheng Chao , Wu Dongxu , Gong Tianyu , Yan Yunshen , Liu Yang , Ji Weixiao , Hou Linrui , Yuan Changzhou 
Published: August 2023

AbstractModest rate behaviors and structural collapse of battery‐type anodes limit the commercial application of lithium‐ion capacitors (LICs). For this, rational design of advanced anodes with both structural stability and high ionic/electronic conductivities becomes essential to advanced LICs. Herein, a general avenue is developed to construct a series of single‐crystal nano‐blocks assembled as “zero‐strain” columbite‐structured MNb2O6 (M = Cd, Co, Zn, Mn, Mg, Ca) accordion frameworks toward LICs. The intrinsic Li+ (de)insertion involves a solid‐solution charge storage mechanism with a volumetric change of <0.59% over (de)lithiation as established with systematical in(ex) situ analysis. The MNb2O6 exhibits M‐dependent electron/ion transport capabilities, along with the highest electronic and Li+ diffusion rates and the smallest volume change (0.32%) for CdNb2O6. Thanks to its robust structure and superb electron/ion conductivities originating from the “internal (i.e., ionic/electronic transport optimization) and external (i.e., structural design) cultivation” design, the CdNb2O6 shows the optimum electrochemical behaviors with a capacity of 102.8 mAh g−1 at 10 A g−1 and capacity retention of 80.3% after 20 000 cycles at 5 A g−1. The assembled CdNb2O6‐based LICs display high‐rate energy density and long‐duration stability. More importantly, the devised strategy provides meaningful guidance for optimum design of next‐generation LICs.
Efficacy of lymph node dissection for duodenal cancer according to the lymph node station
Authors: Miura Yuya , Ohgi Katsuhisa , Ashida Ryo , Yamada Mihoko , Otsuka Shimpei , Sasaki Keiko , Uesaka Katsuhiko , Sugiura Teiichi 
Published: August 2023

AbstractBackgroundLymph node metastasis (LNM) is associated with poor prognosis in patients with duodenal cancer (DC). However, the efficacy and optimal extent of lymph node (LN) dissection have not been thoroughly discussed.MethodsA total of 98 consecutive patients with DC who underwent surgical resection (pancreatoduodenectomy, n = 55; partial resection, n = 32; pancreas‐sparing total duodenectomy, n = 9) were retrospectively analyzed. The LN stations located upstream of the lymphatic flow were defined as Np stations according to tumor location, whereas the others were defined as Nd stations. The association between the dissection of each LN station and survival outcome was investigated using the efficacy index (EI; percentage of metastases to lymph nodes in each station multiplied by the 5‐year survival rate of metastatic cases).ResultsThe survival of patients with LNM at the Nd stations (n = 6) was significantly worse than that of patients with LNM only at the Np stations (n = 20) (relapse‐free survival, median survival time [MST], 6.0 vs. 48.4 months, p < 0.001; overall survival, MST, 15.1 vs. 96.0 months, p < 0.001). Multivariate analysis identified LNM at Nd stations as an independent prognostic factor for overall survival (hazard ratio 9.92; p = 0.015). The Np stations had a high EI (range, 8.34–20.88), whereas the Nd stations had an EI of 0, regardless of the tumor location.ConclusionsLN dissection of the Np stations contributed to acceptable survival, whereas LNM of the Nd stations led to poor survival, possibly reflecting advanced tumor progression to systemic disease in patients with DC.
Risk factors for dementia in older intensive care unit (ICU) survivors
Authors: Wang Sophia , Perkins Anthony J. , Chi Rosalyn , Yates Brandon A. , Khan Sikandar H. , Gao Sujuan , Boustani Malaz , Khan Babar A. 
Published: August 2023

AbstractINTRODUCTIONAs the number of older intensive care unit (ICU) survivors grows, there is an urgent need to identify modifiable risk factors for post‐ICU dementia.METHODSWe performed a secondary data analysis of 3144 ICU patients ≥ 50 years of age without a history of dementia or severe mental illness who were screened as part of the Pharmacological Management of Delirium (PMD) study. Delirium was assessed using the Confusion Assessment Method for the ICU. Dementia was identified using International Classification of Diseases Ninth and Tenth revision codes for dementia or prescription of anti‐dementia medication.RESULTSAverage age (standard deviation) was 65.2 ± 9.5 years; 50.4% were female; and 37.3% were Black. Analyses identified stroke (adjusted hazard ratio [HR] 2.49; 95% confidence interval [CI: 1.52, 4.07], P < 0.001), and depression (adjusted HR 3.03; 95% CI [1.80, 5.10], P < 0.001) as post‐ICU risk factors for dementia.DISCUSSIONFuture studies will need to examine whether interventions targeting post‐ICU stroke and depression can lower dementia incidence in ICU survivors.Highlights
Risk factors for post–intensive care unit (ICU) dementia were distinct from those of Alzheimer's disease.
Cardiovascular risk factors were not associated with dementia in older ICU survivors.
Post‐ICU stroke was associated with a higher risk of dementia in older ICU survivors.
Post‐ICU depression was associated with a higher risk of dementia in older ICU survivors.
Total Synthesis of Metaphanine and Oxoepistephamiersine
Authors: Sun Ya‐Kui , Qiao Jin‐Bao , Xin Yu‐Meng , Zhou Qin , Ma Zhi‐Hua , Shao Hui , Zhao Yu‐Ming 
Published: August 2023

AbstractHerein, we report a concise and divergent synthesis of the complex hasubanan alkaloids metaphanine and oxoepistephamiersine from commercially available and inexpensive cyclohexanedione monoethylene acetal. Our synthesis features a palladium‐catalyzed cascade cyclization reaction to set the tricyclic carbon framework of the desired molecules, a regioselective Baeyer–Villiger oxidation followed by a MeNH2 triggered skeletal reorganization cascade to construct the benzannulated aza[4.4.3]propellane, and a strategically late‐stage regio‐/diastereoselective oxidative annulation of sp3 C−H bond to form the challenging THF ring system and hemiketal moiety in a single step. In addition, a highly enantioselective alkylation of cyclohexanedione monoethylene acetal paved the way for the asymmetric synthesis of target molecular.
Enhanced Active Sites and Stability in Nano‐MOFs for Electrochemical Energy Storage through Dual Regulation by Tannic Acid
Authors: Lu Yibo , Zhang Guangxun , Zhou Huijie , Cao Shuai , Zhang Yi , Wang Shuli , Pang Huan 
Published: August 2023

AbstractThe limited active sites and poor acid‐alkaline solution stability of metal–organic frameworks (MOFs), significantly limit their wider application. In this study, the acid property of tannic acid (TA) was used as an etchant to etch the surface‐active sites. Subsequently, the further chelation of the protonated TA with the exposed metal active site can effectively protect the metal ions. Meanwhile, the TA provided a large amount of phenolic hydroxyl groups, which can greatly improve the stability of imidazolate‐coordinated MOFs. The electrochemical test results indicated that the MOFs composite materials synthesized using this scheme had high specific capacitance and stability. And the mechanism of its electrochemical reaction process was explored through in situ X‐ray diffraction (XRD) and theoretical calculations. In addition, the same treatment was carried out through a series of carboxyl‐coordinated MOFs, which further confirmed the principle of this scheme to obtain a higher active site and stability. This paper explains the mechanism of functionalization of nano‐MOFs by polyphenolic compounds, providing new ideas for the research of nano‐MOFs.
Janus‐Type ESIPT Chromophores with Distinctive Intramolecular Hydrogen‐bonding Selectivity
Authors: Chen Yahui , Lu Sheng , Abbas Abedi Syed Ali , Jeong Minseok , Li Haidong , Hwa Kim Myung , Park Sungnam , Liu Xiaogang , Yoon Juyoung , Chen Xiaoqiang 
Published: August 2023

AbstractExcited‐state intramolecular proton transfer (ESIPT)‐based solid luminescent materials with multiple hydrogen bond acceptors (HBAs) remain unexplored. Herein, we introduced a family of Janus‐type ESIPT chromophores featuring distinctive hydrogen bond (H‐bond) selectivity between competitive HBAs in a single molecule. Our investigations showed that the central hydroxyl group preferentially forms intramolecular H‐bonds with imines in imine‐modified 2‐hydroxyphenyl benzothiazole (HBT) chromophores but tethers the benzothiazole moiety in hydrazone‐modified HBT chromophores. Imine‐derived HBTs generally exhibit higher fluorescence efficiency, while hydrazone‐derived HBTs show a reduced overlap between the absorption and fluorescence bands. Quantum chemical calculations unveiled the molecular origins of the biased intramolecular H‐bonds and their impact on the ESIPT process. This Janus‐type ESIPT chromophore skeleton provides new opportunities for the design of solid luminescent materials.
Functional analysis of a NPC1 gene from the whitefly, Bemisia tabaci (Hemiptera: Aleyrodidae)
Authors: Yu Hao , Wang Liuhao , Liu Shunxiao , Chen Xiaohui , Wei Xiaoyu , Niu Chenxi , Volodymyr Vlasenko , Song Qisheng , Zhang Hongwei 
Published: August 2023

AbstractNiemann‐Pick C (NPC) disease is a neurodegenerative disorder related to cellular sterol trafficking and mutation of NPC1 gene is the main cause for this disease. The function of NPC1 have been reported in a few insects but rarely studied in hemipterans. In the present study, we investigate the function of NPC1 in a hemipteran pest, the whitefly Bemisia tabaci. It was found that B. tabaci had only one NPC1 homolog (BtNPC1), in contrast to two homologs in many other insects. BtNPC1 was ubiquitously expressed at all developmental stages and body parts of whiteflies, with the highest level in adult abdomen, and the expression of BtNPC1 was induced by cholesterol feeding. To further investigate the function of BtNPC1, leaf‐mediated RNA interference experiments were carried out. Results showed that knockdown of BtNPC1 led to reduced survival of whiteflies, as well as reduced fecundity. Moreover, knockdown of BtNPC1 affected the development and metamorphosis of whitefly nymphs. Taken these together, we conclude that BtNPC1 played a crucial role in sterol‐related biological processes of B. tabaci and might be used as an insecticide target for development of novel pest management approaches.
Research progress on animal environment and welfare
Authors: Li Baoming , Wang Yang , Rong Li , Zheng Weichao 
Published: August 2023

AbstractAnimal welfare closely depends on its ability to adapt and thrive in a harmonious relationship with its environment, ensuring both physical and psychological well‐being. Over the years, the welfare of farm animals has gathered global attention and has become increasingly important to the general public and scientific communities. The connection between the environment and animal welfare is primarily established through the provision of suitable and controllable environment for animals. However, it is essential to recognize that the impact of environment extends beyond merely ensuring freedom from discomfort. The environment plays a crucial role in shaping an animal's response to challenges such as disease, stress, and pathogen. While animals may be housed in controlled environments that provide optimal conditions for health, production, and welfare, it is important to acknowledge that specific scenarios can significantly affect and alter the environmental requirements. Even with access to fresh air, certain factors can have a substantial impact on the well‐being of animals. Furthermore, providing appropriate environmental conditions goes beyond meeting basic needs and can greatly contribute to allowing animals to engage in their natural behaviors. It serves as a relevant tool for ensuring and maintaining adequate welfare standards. This review takes a comprehensive approach to environmental welfare by considering the welfare of animals managed in different stocking systems, considering environmental stress, stocking systems, and the provision of environmental enrichment items. By examining these factors, a broader understanding of the relationship between environment and welfare is achieved and recommendations for future research are outlined.
Schienenanbindung der Festen Fehmarnbeltquerung
Authors: Henke Sascha , Hoffmann Mario , Sander Melanie , Molzahn Michael , Heß Michael 
Published: August 2023

AbstractDie Schienenanbindung der Festen Fehmarnbeltquerung ist eines der Top‐3‐Infrastrukturprojekte in Europa, das einen durchgängigen, elektrifizierten Zugverkehr zwischen Skandinavien und Deutschland ermöglichen soll. Im Rahmen dieser ca. 85 km langen Infrastrukturmaßnahme werden neben der Strecke auch zahlreiche Ingenieur‐ und Kunstbauwerke errichtet, für die jeweils eine baugrundtechnische Beurteilung erforderlich ist. Im Rahmen der seit mehreren Jahren laufenden Planung wurden und werden umfangreiche Untersuchungen zur Beurteilung der Baugrundverhältnisse im Projektgebiet durchgeführt. Hierbei zeigt sich, dass aufgrund der glazial geprägten Entstehungsgeschichte der Böden im östlichen Schleswig‐Holstein bereichsweise sehr wechselhafte und gründungstechnisch herausfordernde Baugrundsituationen angetroffen werden. Im Rahmen dieses Beitrags werden die geologischen und geotechnischen Herausforderungen anhand von verschiedenen Beispielsituationen diskutiert und die aktuell erarbeiteten Lösungen kurz skizziert.
Huangqi Jianzhong Tang treats chronic atrophic gastritis rats by regulating intestinal flora and conjugated bile acid metabolism
Authors: Zhang Hui , Huang Xingyue , Wang Guohong , Liu Yuetao 
Published: August 2023

AbstractHuangqi Jianzhong Tang (HQJZ) is effective for treating chronic atrophic gastritis (CAG). The present study was carried out to reveal the mechanism of HQJZ in CAG rats. The metabolism and microbial composition of the cecal contents in CAG rats were analyzed through the integration of an untargeted metabolomic approach using ultra‐high‐performance liquid chromatography coupled with the quadrupole–time of flight mass spectrometry (UHPLC–QTOF–MS) and 16S rRNA gene sequencing, respectively. Finally, MetOrigin analyses were performed to explore the relationship between differential metabolites and intestinal flora. The results showed that HQJZ could significantly regulate metabolic disorders, especially conjugated acid metabolites. 16S rRNA gene sequencing analysis illustrated that HQJZ decreased the abundance of Acetobacter, Desulfovibrio, Escherichia, and Shigella. MetOrigin metabolite traceability analysis showed that the six bile acids associated with HQJZ efficacy included three bacteria–host cometabolites, which were involved in the primary bile acid biosynthesis pathway. Research presented here confirmed that conjugated bile acid metabolism was key to the treatment of CAG by HQJZ and correlates strongly with Bacteroides acidifaciens and Prevotella copri. These findings provide new insights into the mechanisms to explain the efficacy of HQJZ.
The role of CEO regulatory focus in increasing or reducing corporate carbon emissions
Authors: Wagner Andreas , Fischer‐Kreer Denise 
Published: August 2023

AbstractThis article contributes to the emerging stream of corporate carbon emission research, which zooms in on CEOs' responsibility in organizations' strategic decision‐making. This investigation offers new knowledge of how a CEO's regulatory focus can shape whether firms reduce their carbon footprints. Building on regulatory focus theory, this study proposes how the two distinct motivational dispositions (i.e., promotion or prevention focus) of a CEO relate to corporate carbon emissions. We empirically analyzed S&P 500 firms from 2007 to 2018. The findings indicate that CEOs with a high promotion focus are positively associated with corporate carbon emissions, whereas CEOs with a high prevention focus are negatively linked to corporate carbon emissions, with the latter relationship weakened by industry volatility. The findings reported in this study enrich carbon emission research by devoting attention to cognitive and motivational aspects of CEOs for corporate carbon management.
An overview of Brazilian companies' readiness to implement industrial symbiosis
Authors: Agudo Fabiana Liar , Bezerra Bárbara Stolte , Gobbo Júnior José Alcides 
Published: August 2023

AbstractIndustrial symbiosis (IS) is a strategy that focuses on the exchange of resources between colocated industries. Despite the benefits of IS, companies often face challenges in implementing it, primarily due to technical, economic, and information barriers. Therefore, this paper aims to investigate the feasibility of implementing IS among Brazilian companies. To achieve this, a survey was conducted with 201 colocated companies using a previously developed instrument to assess their levels of symbiotic readiness. The findings resulted in the creation of a typology of symbiotic readiness levels, accompanied by practical recommendations for each level. In general, the surveyed companies are making progress toward implementing IS, as evidenced by their attempts to exchange waste and by‐products with other colocated industries. However, overcoming barriers related to information sharing, trust‐building, access conditions, infrastructure, and partnership formation remains challenging. This study provides valuable evidence from an emerging country regarding the readiness levels of companies to implement IS, offering insights and recommendations for managers and public authorities to promote IS. It is important to note that as companies reach mature stages of IS implementation, they can collaborate to transform the conditions of the industrial parks, ultimately fostering future industrial ecosystems.
Stable Dication Diradicals of Triply Fused Metallo Chlorin‐Porphyrin Heterodimers: Impact of the Bridge on the Control of Spin Coupling to Reactivity
Authors: Shah Syed Jehanger , Pandit Younis Ahmad , Garribba Eugenio , Ishida Masatoshi , Rath Sankar Prasad 
Published: August 2023

AbstractWe report an unexpected rearrangement, controlled by the nature of the bridge, leading to the formation of novel, remarkably stable triply fused dinickel(II)/dicopper(II) chlorin‐porphyrin dication diradical heterodimers in excellent yields. Here, a dipyrromethene bridge gets completely fused between two porphyrin macrocycles with two new C−C and one C−N bonds. The two macrocycles exhibit extensive π‐conjugation through the bridge, which results in an antiferromagnetic coupling between the two π‐cation radicals. In addition, the macrocyclic distortion also favours a rare intramolecular ferromagnetic interaction between the CuII and π‐cation radical spins to form a triplet state. The structural and electronic perturbation in the unconjugated dication diradical possibly enables the bridging pyrrolic nitrogen to undergo a nucleophilic attack at the nearby β‐carbon of the porphyrin π‐cation radical with a computed free energy barrier of >20 kcal mol−1 which was supplied in the form of reflux condition to initiate such a rearrangement process. UV‐vis, EPR and ESI‐MS spectroscopies were used to monitor the rearrangement process in situ in order to identify the key reactive intermediates leading to such an unusual transformation.
Balancing and Therapeutic Roles of CXCR4‐Inhibiting Nanomedicine via Synergetic Regulation of Hepatic Stellate Cells and Extracellular Matrix in Liver Injury†
Authors: Huan Xu , Chen Yi , Wu Xiaozhen , Wang Hui , Yang Ying , Wu Pengkai , Liu Tianqing , Wang Kaikai , Ding Dan 
Published: August 2023

Comprehensive SummaryInflammation is associated with different stages of liver disease, including acute injury, fibrosis, cirrhosis, and hepatoma. During the progression of liver inflammation, activation of hepatic stellate cells (HSCs) and extracellular matrix (ECM) deposition are critical pathologies, and thus the combined therapy using HSCs and ECM as targets represents a promising strategy in the treatment of liver injury. Here, a novel CXCR4‐inhibiting nanomedicine that can simultaneously deliver AMD3100 (CXCR4 antagonist) and siPAI‐1 (siRNA of plasminogen activator inhibitor‐1) was designed and developed to reverse liver fibrosis by inhibiting HSCs activation and degrading ECM deposition. With this goal in mind, a Zn(II) coordinated polymeric AMD3100 named PAMD/Zn polymer with siRNA delivery and CXCR4 antagonism capabilities was synthesized. Overall, our results suggest that PAMD/Zn recruits pro‐inflammatory cells for fibrogenesis and inhibits the activation of HSCs for fibrolysis at various stages of liver injury. Its use in conjunction with PAI‐1 silencing achieved satisfactory therapeutic efficacy in liver injury and fibrosis. The derivative CXCR4‐inhibiting nanomedicine is a versatile platform that offers valuable benefits for the treatment of liver diseases.
Chloride‐Bridged Dimeric SalphenZr(IV) Cobaltate Catalyst Unleashes the Potential of Base‐Free Carbonylative Polymerization for Biodegradable PHAs†
Authors: Ganesan Vinothkumar , Yoon Sungho 
Published: August 2023

Comprehensive SummaryPoly(3‐hydroxyalkanoates) (PHAs) are a promising class of biodegradable polymers, exhibiting properties comparable to traditional petroleum‐based counterparts. Nonetheless, the widespread commercialization of PHAs is hindered by the absence of an efficient and economically viable catalytic system, impeding their competitiveness against non‐biodegradable polymers. In an effort to address this challenge, we present a study on a newly developed chloro‐bridged dimeric salphen zirconium cobaltate complex for the direct synthesis of PHAs via carbonylative polymerization of epoxides. The catalytic system demonstrates favorable activity under mild reaction conditions, enabling complete monomer conversion and an impressive 92% selectivity towards PHA formation. Through meticulous control experiments and mechanistic studies, we have gained crucial insights into the polymerization process. Remarkably, our findings challenge the prevailing notion of sequential ring‐opening polymerization of in‐situ generated β‐lactones as the primary pathway. Instead, we demonstrate that the polymerization predominantly proceeds through direct co‐polymerization of epoxide and carbon monoxide, unveiling a unique and efficient mechanism for PHA synthesis.