bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimization of hybrid friction stir welding of PMMA: 3D-printed parts and conventional sheets welding efficiency in single- and two-axis welding traces
Authors: Petousis Markos , Mountakis Nikolaos , Vidakis Nectarios 
Published: June 2023

AbstractHerein, the feasibility of joining with the friction stir welding (FSW) process 3D-printed parts made of poly(methyl methacrylate) (PMMA) with extruded PMMA sheets is investigated. A full factorial design method is followed, with two control parameters, i.e., tool rotational and travel speed, and three levels each. The hybrid joints produced were subjected to tensile and flexural loading and the corresponding properties were optimized with statistical modeling tools. Regression analysis provided prediction models for the five output metrics. The temperature was monitored throughout the experimental process. Samples were inspected with optical and scanning electron microscopy and their morphological characteristics were correlated with the joining conditions. The optimized FSW parameters were used for joining PMMA 3D-printed parts with sheets with two-axis joining seams. The produced hybrid joints were more than sufficient in their mechanical properties. The highest welding efficiency achieved in the tensile tests was 1.36, by the sample welded with 900 rpm and 6 mm/min. The sample welded with the same conditions achieved also the highest welding efficiency in the flexural tests (0.98). The findings presented proven the efficiency of the hybrid PMMA joints studied and have direct industrial applications for efficient component production.
Graphical Abstract
Prevalence and characteristics of benign cartilaginous tumours of the shoulder joint. An MRI-based study
Authors: Woltsche Johannes Nikolaus , Smolle Maria , Szolar Dieter , Bergovec Marko , Leithner Andreas 
Published: June 2023

Abstract

Objective
Enchondromas (EC) of the shoulder joint are benign intraosseous cartilage neoplasms, with atypical cartilaginous tumours (ACT) representing their intermediate counterpart. They are usually found incidentally on clinical imaging performed for other reasons. Thus far the prevalence of ECs of the shoulder has been analysed in only one study reaching a figure of 2.1%.

Materials and methods
The aim of the current study was to validate this number via retrospective analysis of a 45 times larger, uniform cohort consisting of 21.550 patients who had received an MRI of the shoulder at a single radiologic centre over a time span of 13.2 years.

Results
Ninety-three of 21.550 patients presented with at least one cartilaginous tumour. Four patients showed two lesions at the same time resulting in a total number of 97 cartilage tumours (89 ECs [91.8%], 8 ACTs [8.2%]). Based on the 93 patients, the overall prevalence was 0.39% for ECs and 0.04% for ACTs. Mean size of the 97 ECs/ACTs was 2.3 ± 1.5 cm; most neoplasms were located in the proximal humerus (96.9%), in the metaphysis (60.8%) and peripherally (56.7%). Of all lesions, 94 tumours (96.9%) were located in the humerus and 3 (3.1%) in the scapula.

Conclusion
Frequency of EC/ACT of the shoulder joint appears to have been overestimated, with the current study revealing a prevalence of 0.43%.
Which patient-specific parameters correlate with operation time for total hip arthroplasty? — A retrospective analysis of the direct anterior approach
Authors: von Hertzberg-Boelch Sebastian , Mueller Laura , Stratos Ioannis , Arnholdt Joerg , Holzapfel Boris , Rudert Maximilian 
Published: June 2023

Abstract
Purpose
The current study aims to identify patient-specific factors that correlate with operation time for total hip arthroplasty (THA) performed via the direct anterior approach (DAA).

Methods
In this retrospective study, patient-specific factors were tabulated from the charts and measured from preoperative templating radiographs. These factors were correlated with operation time by bivariate analysis. Significant factors were used for stepwise multiple regression analysis.

Results
Nine hundred-sixty procedures were included. BMI (R = 0.283), the distance from the superior iliac spine to the greater trochanter (DAA Plane) (R = − 0.154), patients age (R = 0.152) and the abdominal fat flap (R = 0.134) showed the strongest correlations (p < 0.005) with operation time. The multiple regression model including BMI, Kellgren and Lawrence Score, Age, DAA Plane and the Canal to Calcar ratio had the best predictive accuracy (corrected R2 = 0.122).

Conclusions
Patient-specific factors that make the entry into the femur difficult correlate significantly with operation time of THA via the DAA.
ICP, PRx, CPP, and ∆CPPopt in pediatric traumatic brain injury: the combined effect of insult intensity and duration on outcome
Authors: Svedung Wettervik Teodor , Velle Fartein , Hånell Anders , Howells Timothy , Nilsson Pelle , Lewén Anders , Enblad Per 
Published: June 2023

Abstract
Purpose
The aim was to investigate the combined effect of insult intensity and duration, regarding intracranial pressure (ICP), pressure reactivity index (PRx), cerebral perfusion pressure (CPP), and optimal CPP (CPPopt), on clinical outcome in pediatric traumatic brain injury (TBI).

Method
This observational study included 61 pediatric patients with severe TBI, treated at the Uppsala University Hospital, between 2007 and 2018, with at least 12 h of ICP data the first 10 days post-injury. ICP, PRx, CPP, and ∆CPPopt (actual CPP-CPPopt) insults were visualized as 2-dimensional plots to illustrate the combined effect of insult intensity and duration on neurological recovery.

Results
This cohort was mostly adolescent pediatric TBI patients with a median age at 15 (interquartile range 12–16) years. For ICP, brief episodes (minutes) above 25 mmHg and slightly longer episodes (20 min) of ICP 20–25 mmHg correlated with unfavorable outcome. For PRx, brief episodes above 0.25 as well as slightly lower values (around 0) for longer periods of time (30 min) were associated with unfavorable outcome. For CPP, there was a transition from favorable to unfavorable outcome for CPP below 50 mmHg. There was no association between high CPP and outcome. For ∆CPPopt, there was a transition from favorable to unfavorable outcome when ∆CPPopt went below −10 mmHg. No association was found for positive ∆CPPopt values and outcome.

Conclusions
This visualization method illustrated the combined effect of insult intensity and duration in relation to outcome in severe pediatric TBI, supporting previous notions to avoid high ICP and low CPP for longer episodes of time. In addition, higher PRx for longer episodes of time and CPP below CPPopt more than −10 mmHg were associated with worse outcome, indicating a potential role for autoregulatory-oriented management in pediatric TBI.
Assessing balance in people with bilateral vestibulopathy using the Mini-Balance Evaluation Systems Test (Mini-BESTest): feasibility and comparison with healthy control data
Authors: Zhu Meichan , van Stiphout Lisa , Karabulut Mustafa , Pérez Fornos Angélica , Guinand Nils , Meijer Kenneth , van de Berg Raymond , McCrum Christopher 
Published: June 2023

Abstract
Objectives
Bilateral vestibulopathy (BVP) leads to unsteadiness when walking, which worsens in darkness or on uneven ground, as well as falls. Since simple balance tests struggle to distinguish between BVP and healthy participants, we aimed (1) to test if the Mini-BESTest is feasible in BVP, (2) how people with BVP perform on the Mini-BESTest and (3) to compare these scores with healthy reference data.

Methods
Fifty participants with BVP completed the Mini-BESTest. 12-month falls incidence was obtained by questionnaire. To compare the overall and sub-scores between our participants with BVP and those of healthy participants from the literature (n = 327; obtained via PubMed searches), Mann–Whitney U tests were used. Sub scores within the BVP group were also compared. Spearman correlations were used to investigate the relationships between Mini-BESTest score and age.

Results
No floor or ceiling effects were observed. Participants with BVP had significantly lower Mini-BESTest total scores than the healthy group. Anticipatory, reactive postural control and sensory orientation sub scores of the Mini-BESTest were significantly lower in BVP, while dynamic gait sub scores were not significantly different. A stronger negative correlation between age and Mini-BESTest total score was found in BVP than in the healthy group. Scores did not differ between patients with different falls history.

Conclusion
The Mini-BESTest is feasible in BVP. Our results confirm the commonly reported balance deficits in BVP. The stronger negative association between age and balance in BVP might reflect the age-related decline in the remaining sensory systems with which people with BVP compensate.
“Make it the done thing”: an exploration of attitudes towards rest breaks, productivity and wellbeing while working from home
Authors: Walker Lucy , Braithwaite Elizabeth C. , Jones Marc V. , Suckling Steve , Burns Danielle 
Published: June 2023

Abstract
Objective
Taking regular rest breaks while working positively impacts productivity and wellbeing. While home and hybrid working styles have become a popular choice for employees, the impact of, and perceptions towards, taking breaks while working at home is poorly understood. The current research aimed to explore attitudes towards taking rest breaks while working from home and capture levels of breaks taken, wellbeing and productivity in a sample of UK white-collar workers.

Methods
A mixed method approach was applied where self-report data from an online survey were gathered from individuals (N = 140) from one organisation. Open-ended questions regarding attitudes and perceptions towards rest break behaviours were obtained. Further quantitative measures included the number of breaks taken while working from home, levels of productivity (measured by the Health and performance Presenteeism subscale) and mental wellbeing (measured by the Short Warwick-Edinburgh Mental wellbeing scale). Both quantitative and qualitative analysis approaches were applied.

Results
Qualitative responses indicated two overarching themes (1) Personal and (2) Organisational sat above four further themes including Movement outside, Structure of home working, Home environment and Digital presence. Additionally, quantitative findings indicated that the number of breaks taken outside was associated with positive changes in wellbeing.

Conclusion
Employers could aim to support employees working from home in taking outside breaks through flexible working patterns, authentic leadership, and a change in company social norms around break behaviours. Such organisational changes could help to improve workforce productivity and wellbeing.
Mass spectrometry-based metabolite profiling reveals functional seasonal shifts in the metabolome of Zygophyllum dumosum Boiss and its relation to environmental conditions
Authors: Sikron-Persi Noga , Granot Gila , Batushansky Albert , Toubiana David , Grafi Gideon , Fait Aaron 
Published: June 2023

Abstract
Main conclusion
A multi-year study of perennial Z. dumosum shows a consistent seasonal pattern in the changes of petiole metabolism, involving mainly organic acids, polyols, phenylpropanoids, sulfate conjugates, and piperazines.

Abstract
GC–MS and UPLC–QTOF-MS-based metabolite profiling was performed on the petioles of the perennial desert shrub Zygophyllum dumosum Boiss (Zygophyllaceae). The petioles, which are physiologically functional throughout the year and, thus, exposed to seasonal rhythms, were collected every month for 3 years from their natural ecosystem on a southeast-facing slope. Results showed a clear multi-year pattern following seasonal successions, despite different climate conditions, i.e., rainy and drought years, throughout the research period. The metabolic pattern of change encompassed an increase in the central metabolites, including most polyols, e.g., stress-related D-pinitol, organic and sugar acids, and in the dominant specialized metabolites, which were tentatively identified as sulfate, flavonoid, and piperazine conjugates during the summer–autumn period, while significantly high levels of free amino acids were detected during the winter–spring period. In parallel, the levels of most sugars (including glucose and fructose) increased in the petioles at the flowering stage at the beginning of the spring, while most of the di- and tri-saccharides accumulated at the beginning of seed development (May–June). Analysis of the conserved seasonal metabolite pattern of change shows that metabolic events are mostly related to the stage of plant development and its interaction with the environment and less to environmental conditions per se.
Only one beer can be mortal: a case report of two sisters with cardiac arrest due to a homozygous mutation in PPA2 gene
Authors: Manzanilla-Romero Héctor Hugo , Schermer Elisabeth , Mayr Agnes , Rudnik-Schöneborn Sabine 
Published: June 2023

AbstractWe report the long way to the correct diagnosis in two teenage sisters who developed a cardiac arrest after consuming minimal amounts of alcohol. The older girl dramatically survived two cardiac arrests at the age of 14 and 15 years. She underwent an extensive examination that revealed isolated cardiac abnormalities including fibrosis, dilated cardiomyopathy and inflammation. The younger girl also had a cardiac arrest at the age of 15 and died suddenly after consuming 1–2 beers, 3 years after her sister´s first incident. Autopsy of the heart revealed acute myocarditis without structural alterations. Multigene panel analysis (not including PPA2) showed SCN5A and CACNA1D variants in both sisters and their healthy mother. Six years later duo exome allowed the diagnosis of an autosomal recessive PPA2-related mitochondriopathy. We discuss the molecular results and clinical picture of our patients compared to other PPA2-related cases. We highlight the diagnostic contribution of multigene panels and exome analysis. The genetic diagnosis is important for medical care and for everyday life, specifically because alcohol intake can result in cardiac arrest and should be strictly avoided. Conclusion: Duo exome sequencing clarified the diagnosis of PPA2-related mitochondriopathy in two sisters with isolated cardiac features and sudden cardiac arrest triggered by minimal amounts of alcohol.

What is Known:• Multigene-Panel or exome analysis is a valuable tool to identify genetic causes of hereditary cardiac arrhythmias.• Variants of unknown significance can lead to misinterpretation. PPA2-related mitochondriopathy is a very rare autosomal recessive condition that is normally fatal in infancy.

What is New:• Duo exome analysis in two teeenage sisters with cardiac arrest revealed a homozygous mild PPA2 mutation as the underlying pathology restricted to the heart muscle
High risk of non-cancer mortality in bladder cancer patients: evidence from SEER-Medicaid
Authors: Wang Shunde , Ge Chengguo 
Published: June 2023

Abstract
Purpose
The objective of this study was to investigate non-cancer causes of death and associated risk factors after bladder cancer (BC) diagnosis.

Methods
Eligible BC patients were obtained from the SEER database. SEER*Stat software 8.3.9.2 was used to calculate the standardized mortality ratios (SMRs). The proportions of different non-cancer cause of death were calculated and analyzed in different follow-up periods. Multivariate competing risk model was used to analyze the risk factors for death of BC and non-cancer diseases.

Results
In total, 240,954 BC patients were included and 106,092 patients experienced death, with 37,205 (35.07%), 13,208 (12.45%) and 55,679 (52.48%) patients experienced BC, other cancer and non-cancer disease-related deaths, respectively. Overall SMR for BC patients who died from non-cancer diseases was 2.42 (95% CI [2.40–2.44]). Cardiovascular diseases were the most common non-cancer cause of death, followed by respiratory diseases, diabetes mellitus, and infectious diseases. Multivariate competing risk analysis identified the following high-risk factors for non-cancer mortality: age > 60 years, male, whites, in situ stage, pathological type of transitional cell carcinoma, not receiving treatment (including surgery, chemotherapy, or radiation), and widowed.

Conclusions
Cardiovascular diseases are the leading non-cancer cause of death in BC patients, followed by respiratory disease, diabetes mellitus and infectious diseases. Physicians should pay attention to the risk of death from these non-cancer diseases. Also, physicians should encourage patients to engage in more proactive self-surveillance and follow up.
Increasing knowledge of the transmissivity field of a detrital aquifer by geostatistical merging of different sources of information
Authors: Pardo-Igúzquiza Eulogio , Dowd Peter A. , Luque-Espinar Juan A. , Chica-Olmo Mario 
Published: June 2023

AbstractTransmissivity is a significant hydrogeological parameter that affects the reliability of groundwater flow and transport models. This study demonstrates the improvement in the estimated transmissivity field of an unconfined detritic aquifer that can be obtained by using geostatistical methods to combine three types of data: hard transmissivity data obtained from pumping tests, soft transmissivity data obtained from lithological information from boreholes, and water head data. The piezometric data can be related to transmissivity by solving the hydrogeology inverse problem, i.e., including the observed water head to determine the unknown model parameters (log transmissivities). The geostatistical combination of all the available information is achieved by using three different geostatistical methodologies: ordinary kriging, ordinary co-kriging and inverse problem universal co-kriging. In addition, there are eight methodological cases to be compared according to which log-transmissivity data are considered as the primary variable in co-kriging and whether two or three variables are used in inverse-problem universal co-kriging. The results are validated by using the performance statistics of the direct modelling of the unconfined groundwater flow and comparing observed water heads with the modelled ones. Although the results show that the two sets of log-transmissivity data are incompatible, the set of log-transmissivity data from the lithofacies provides a good log-transmissivity image that can be improved by inverse modelling. The map provided by inverse-problem universal co-kriging provides the best results. Using three variables, rather than two in the inverse problem, gives worse results because of the incompatibility of the log-transmissivity data sets.
African jewel fish (Hemichromis bimaculatus) distinguish individual faces based on their unique iridophore patterns
Authors: Coss Richard G. , Tyler Carol Lee 
Published: June 2023

AbstractPrevious research has shown that African jewel fish (Hemichromis bimaculatus) recognize pair-bonded mates during their exchanges of egg-guarding duties. The current research examined the perceptual cues for face recognition by comparing two face models displaying anatomically realistic arrangements of blue iridophores derived from discriminant function analysis of distinct sibling groups. Four groups each consisting of 9 subadults were examined using a narrow compartment restraining lateral movement where face models were presented at eye level for eight trials. Because respiratory movement of the operculum can mechanically displace the eye thereby shifting the retinal image, jewel fish reduce their respiration rate during increased attention. When two experimental groups were presented with the same face models on four trials following initial model presentations, both groups exhibited stable respiration rates indicative of model habituation. When the habituated face models were switched to novel face models on the fifth trial, the rates of respiration decreased as measured by reliable increases in the elapsed times of opercular beats. Switching the models back to the habituated models on the sixth trial caused reliable decreases in the elapsed times of opercular beats, resembling the earlier trials for the habituated models. Switching the face models again to the formerly novel models on the seventh trial produced respiration rates that resembled those of the habituated models. The two control groups viewing the same models for all eight trials exhibited no substantial change in respiration rates. Together, these findings indicate that jewel fish can learn to recognize novel faces displaying unique arrangements of iridorphores after one trial of exposure.
Optimizing hydrogen production by alkaline water decomposition with transition metal-based electrocatalysts
Authors: Li Jingjing , Jing Zhengyin , Bai Haotian , Chen Zhonghao , Osman Ahmed I. , Farghali Mohamed , Rooney David W. , Yap Pow-Seng 
Published: June 2023

AbstractBurning fossil fuels account for over 75% of global greenhouse gas emissions and over 90% of carbon dioxide emissions, calling for alternative fuels such as hydrogen. Since the hydrogen demand could reach 120 million tons in 2024, efficient and large-scale production methods are required. Here we review electrocatalytic water splitting with a focus on reaction mechanisms, transition metal catalysts, and optimization strategies. We discuss mechanisms of water decomposition and hydrogen evolution. Transition metal catalysts include alloys, sulfides, carbides, nitrides, phosphides, selenides, oxides, hydroxides, and metal-organic frameworks. The reaction can be optimized by modifying the nanostructure or the electronic structure. We observe that transition metal-based electrocatalysts are excellent catalysts due to their abundant sources, low cost, and controllable electronic structures. Concerning optimization, fluorine anion doping at 1 mol/L potassium hydroxide yields an overpotential of 38 mV at a current density of 10 mA/cm2. The electrocatalytic efficiency can also be enhanced by adding metal atoms to the nickel sulfide framework.
The antecedents of moral identity: A meta-analytic review
Authors: Xu Xiaofeng , Li Miaomiao , Kwan Ho Kwong , Zhang Xiaomeng 
Published: June 2023

Abstract
Moral identity is an important self-concept. Taking a social cognitive perspective, we propose an integrative framework to examine the relationships between moral identity and its antecedents, including demographic variables, personality traits, and organizational contexts (specifically leadership style and ethical climate). An analysis of the effect sizes in 110 studies involving 44,441 participants shows that gender, personality traits, and organizational context are strongly associated with moral identity. The moral identity measure used, cultural tendencies toward individualism or collectivism, and demographic characteristics moderate the relationships between moral identity and its antecedents. The significance and implications of the factors that influence moral identity are discussed.