bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of Diet Variation on Growth Performance, Feeding Efficiency, Health Condition and Water Quality of Juvenile Short-finned Eel (Anguilla bicolor).
Authors: Wahyudi Annisa Apriliani , Ching Fui Fui , Senoo Shigeharu 
Published: February 2025

This study aimed to assess the effects of three different types of feed on the growth and feeding performance, water quality and health condition of short-finned eel (Anguilla bicolor) juvenile. This experiment was conducted for 31 days and involved a total of 180 fish with initials of body weight of 202.89±3.80 g and total length of 44.33±0.6 cm. The fish were divided into three groups , with each group were fed with different types of diets: 1) Japfa dough feed (JDF), 2) dough feed made of from grinded marine pellet (GDF) and 3) pelleted feed (PF). Each treatment was prepared in triplicate. The findings revealed that the pellet-type feed (PF) significantly improved the overall growth performance including survival rate (100.00%) and specific growth rate (3.176±1.08 %/day) with excellent feeding performance recorded with lower feed conversion ratio (2.15±0.9) and high protein efficiency ratio (1.15±0.45). Histological examination of the intestine and liver showed no notable differences in condition of fish in all treatments. In conclusion, this study demonstrated that PF is an effective feed and beneficial for improving growth and feeding performance while maintaining health condition of short-finned eel juveniles hence it suggests the potential for developing a promising feed in the future for eel aquaculture industry.
Precision in Uric Acid Detection: Unlocking Higher Sensitivity with Zinc Oxide-Coated Tapered No-Core Fibre-Based Sensor
Authors: Ahmad Zaini Muhammad Ilham , Azmi Mohamad Farid Izuan , Ahmad Noorden Ahmad Fakhrurrazi , Daud Suzairi 
Published: February 2025

In this paper, ZnO coated non tapered and tapered no-core fibre (NCF) were developed and experimentally demonstrated for the detection of changes in the uric acid (UA) concentrations. The fabricated main optical fibre-based sensor used non tapered and tapered NCF sandwiched in between SMF region. The tapered NCF by CO2 laser technique to achieve a waist diameter of 19.17 µm. The non tapered NCF was tested under the UA solutions for comparison purposes. The non tapered and tapered NCF sensing regions were then coated with ZnO solution using the dip-coating method. The ZnO was chosen as the coating due to its remarkable properties such as high transmittance, and good electrical conductivity. It is also known as effective in immobilizing with low isoelectric point (IEP) acidic proteins. Non-tapered UV-Vis spectroscopy was used to characterize the element of the thin composite film. The sensing performance test was performed by using different concentrations of UA solutions ranging from 100 µM to 800 µM for both non tapered and tapered NCF sensors. From the results, the tapered NCF biosensor with a coating of ZnO shows an excellent sensitivity than the non tapered NCF biosensor with the highest sensitivity of 0.00775 ± 0.00072 nm/µM. The reversibility, reproducibility, and reusability test of the designated optical fibre biosensor were also analysed and discussed in this paper.
Fungicide use intensity influences the soil microbiome and links to fungal disease suppressiveness in amenity turfgrass
Authors: Chou Ming-Yi , Patil Apoorva Tarihalkar , Huo Daowen , Lei Qiwei , Kao-Kniffin Jenny , Koch Paul 
Published: February 2025

ABSTRACT

Disease-suppressive soils have been documented in many economically important crops, but not in turfgrass, one of the most intensively managed plant systems in the United States. Dollar spot, caused by the fungus
Clarireedia jacksonii
, is the most economically important disease of managed turfgrass and has historically been controlled through the intensive use of fungicides. However, previous anecdotal observations of lower dollar spot severity on golf courses with less intensive fungicide histories suggest that intensive fungicide usage may suppress microbial antagonism of pathogen activity. This study explored the suppressive activity of transplanted microbiomes against dollar spot from seven locations in the Midwestern U.S. and seven locations in the Northeastern U.S. with varying fungicide use histories. Creeping bentgrass was established in pots containing homogenized sterile potting mix and field soil and inoculated with
C. jacksonii
upon maturity. Bacterial and fungal communities of root-associated soil and phyllosphere were profiled with short-amplicon sequencing to investigate the microbial community associated with disease suppression. The results showed that plants grown in the transplanted soil microbiome collected from sites with lower fungicide intensities exhibited reduced disease severity. Plant growth-promoting and pathogen-antagonistic microbes may be responsible for disease suppression, but further validation is required. Additional least squares regression analysis of the fungicides used at each location suggested that contact fungicides such as chlorothalonil and fluazinam had a greater influence on the microbiome disease suppressiveness than penetrant fungicides. Potential organisms antagonistic to
Clarireedia
were identified in the subsequent amplicon sequencing analysis, but further characterization and validation are required.

IMPORTANCE
Given the current reliance on fungicides for plant disease control, this research provides new insights into the potential non-target effects of repeated fungicide usage on disease-suppressive soils. It also indicates that intensive fungicide usage can decrease the activity of beneficial soil microbes and lead to a more disease conducive microbial environment in turfgrass. The results from this study can be used to identify more sustainable disease management strategies for a variety of economically important and intensively managed pathosystems. Understanding the factors that facilitate disease-suppressive soils will contribute to more sustainable plant protection practices.
Implementation path for public participation in micro-space renovation of old urban communities
Authors: Huang Beina 
Published: February 2025

Background Public participation can not only enhance community residents’ sense of identity and belonging to the renovation project, but also ensure that the renovation project can better meet the needs of residents. Objective This paper aims to comprehensively review and optimize the public participation mechanism in the micro-space transformation of old urban communities through support vector machine algorithm, and establish a collaborative participation mechanism to enhance public participation and promote sustainable community development. Methods Based on the analysis of the current situation and existing problems of micro-space renovation in Shanghai’s old communities, an evaluation model of urban characteristic planning with support vector machine was constructed, and then the performance of the research method was tested and empirically analyzed. Results In the dataset, when the maximum deviation value was 0.7, the accuracy of the mesh optimization method is 0.9739, and when the maximum deviation value is 4.9, the accuracy of the mesh optimization method was 0.9453. Conclusions This study proposes strategies for effective public participation that improve the quality of life of residents and the overall environment of the community.
Association between serum uric acid and the risk of breast cancer: A meta-analysis of observational studies
Authors: Yang Liping , Yu Ziyun , Zhu Jin , He Longbo , Wang Lieliang , Luo Qingfeng 
Published: February 2025

Background The relationship between serum uric acid and breast cancer remains uncertain. This meta-analysis aimed to elucidate the dose-response association between elevated serum uric acid levels and breast cancer risk. Methods We systematically searched PubMed, Embase, and Web of Science for observational studies evaluating serum uric acid and breast cancer risk in adult women. Risk ratios (RRs) with 95% confidence intervals (CIs) were calculated using a random-effects model. Results Ten studies were included. High serum uric acid was associated with an increased breast cancer risk (RR: 1.34; 95% CI: 1.03–1.73; P = 0.03; I2 = 78%). Meta-regression analysis revealed that the cutoff for high serum uric acid positively correlated with breast cancer risk (coefficient = 0.24; P < 0.001), explaining heterogeneity (residual I2 = 0%). Subgroup analysis demonstrated a high serum uric acid was significantly related to an increased breast cancer risk in studies with a cutoff value ≥ 5.4 mg/dL (RR: 1.95; P < 0.001), but not in those with a cutoff value < 5.4 mg/dL (RR: 0.97; P = 0.44). The dose-response meta-analysis revealed a U-shaped association between serum uric acid levels and the risk of breast cancer ( P for nonlinearity = 0.013). The risk of breast cancer fell until around 4.5 mg/dL of serum uric acid, and increased afterward. Conclusion Serum uric acid may be nonlinearly associated with the risk of breast cancer (U-shaped). The risk of breast cancer increases with serum uric acid above 4.5 mg/dL, and a higher association between serum uric acid and the increased risk of breast cancer could be observed in studies with cutoff of serum uric acid  > 5.4 mg/dL.
Welfare Retrenchment, Government Expenditure Structure, and Economic Growth: A Perspective of Marx’s Capital Circulation Theory
Authors: Zhao Feng , Tan Xuan , Huang Yanghua , Feng Zhixuan 
Published: February 2025

This article considers the impact of government expenditure structure on economic growth. We discuss whether welfare retrenchments in European countries are conducive to overcoming debt crises. By introducing the government sector into the circuit of capital model, we consider the ways that different types of government spending act on the accumulation and realization of the total social capital. Our empirical analysis finds that higher welfare spending is favorable to long-run growth, and the more spending there is on public debts the more the growth regime becomes wage led. Therefore, austerity policies that focus on welfare cuts may aggravate the problem of underconsumption and secular stagnation. JEL Classification: E11, H53, O11
Hidradenitis Suppurativa in Pregnancy: A Case Report and Clinical Insights
Authors: Jacob Olivia Marie , Sharmila Vijayan , Garkapati Kavitha 
Published: February 2025

Introduction: Hidradenitis Suppurativa (HS) is a chronic and relapsing acneiform inflammation of the skin, apocrine glands and subcutaneous tissues. It is common among women of the reproductive age group. It is a chronic debilitating condition which may significantly affect the quality of life based on the severity of disease. HS during pregnancy requires additional care and treatment may be challenging in severe or refractory cases. Case: We report a case of HS during pregnancy who presented at term with painful skin lesions. Discussion: Patients with HS are found to have higher chances of adverse maternofoetal outcomes when compared to general population. In cases where there are worsening symptoms, treatment becomes a challenge. A postpartum flare of symptoms may also be debilitating and affect the quality of life in patients. Conclusion: There is a paucity of data for optimal management of HS in pregnancy especially mode of delivery. There is a need for guidelines for the management of skin conditions during pregnancy and its implications.
EXPRESS: Comparing Different Viral Strains in Identifying Risk Factors for the Development of Venous Thromboembolism in Hospitalized COVID-19 Patients
Authors: Panesar Harsimran , Raval Ruchi , Chan Amber Wai-San , Tancredi Jana , Simonian Gregory , O'Connor David J 
Published: February 2025

Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, there have been nearly seven million deaths associated with COVID-19 and over thirteen billion total vaccine doses administered worldwide. This study aimed to evaluate the patient demographics and laboratory values that might help predict individuals at risk of having a DVT formation while hospitalized with COVID-19, focusing on the four major strains alongside the associated vaccination availability periods in the United States to devise risk stratification and management algorithms. This retrospective cohort study analyzed 4,429 COVID-19 positive patients admitted to a single, tertiary care institution from March 2020 - February 2024 who underwent venous duplex ultrasound due to clinical suspicion. Results: It was found that active chemotherapy treatment, higher weight (77.0 vs. 84.0 kg), and longer LOS to first duplex (5 vs. 10 days) were independent predictors of mortality. Additionally, men, older age (68 vs. 70 years old), medical history of DVTs, and longer LOS to first duplex (5 vs. 8 days) were prognostic for DVT formation. More importantly, the prevalence of DVT was not statistically different between each COVID-19 wave, despite diminished mortality and morbidity overtime. These factors should raise clinical suspicion for DVT formation and mortality among physicians. This study also demonstrated many non-predictive variables including COVID-19 as the principal diagnosis, BMI, smoking status, history of atrial fibrillation, stroke, CAD, vaccination status, and all laboratory values. This study helps establish a critical foundation to analyze trends of anticoagulant and systemic corticosteroid use in this COVID-19 patient population.
Effectiveness of an educational intervention on mealtime support needs for people with dementia in residential care facilities: A cluster-randomized controlled trial
Authors: Passos Lígia , Tavares João , Batchelor Melissa , Figueiredo Daniela 
Published: February 2025

Background People with dementia face numerous challenges during mealtimes, including difficulties with food intake, cutlery use, and maintaining attention. These can lead to severe consequences such as malnutrition and aspiration pneumonia, affecting the well-being of these individuals. Aim To determine the effectiveness of an educational intervention in improving mealtime support needs and enhancing the well-being of both individuals with dementia and direct care workers. Methods A cluster-randomized controlled trial was conducted in four residential care facilities. The study involved direct care workers and residents with dementia, with facilities randomly assigned to either an intervention or control group. The intervention comprised three weekly 2-hour training sessions, focusing on dementia-related mealtime challenges and practical support strategies. Data were collected at baseline and one-week post-intervention using questionnaires and observational tools to assess caregivers’ skills, burnout levels, and job satisfaction, as well as residents’ mealtime behavior and food intake. Results Direct care workers from the intervention group showed significant improvements in knowledge ( p < .001; d = 0.728) and skills ( p < .001; d = 0.842) compared to the control group. Additionally, there were notable reductions in burnout levels ( p = .001; d = 0.466) and higher job satisfaction ( p = .003; d = 0.410). People with dementia in the intervention group demonstrated better performance at mealtimes. Conclusion The educational intervention effectively enhanced direct care workers’ abilities to support people with dementia during mealtimes, leading to better outcomes for both caregivers and residents. Implementing such training programs can improve care quality and alleviate challenges in dementia care.
Long-Term Outcomes After Pulmonary Valve Repair for Regurgitation Secondary to Prior Intervention
Authors: Ragheb Daniel Kyrillos , Zhang Yulin , Jaggi Ayush , Maskatia Shiraz A. , Adamson Gregory T. , Lui George K. , Martin Elisabeth , Ma Michael , Hanley Frank L. , McElhinney Doff B. 
Published: February 2025

Purpose Pulmonary valve (PV) regurgitation (PR) secondary to prior repair of congenital heart disease commonly necessitates intervention, typically with PV replacement (PVR). However, prosthetic valves are susceptible to degeneration and ultimately require reintervention. Pulmonary valve repair (PVr) can correct PR while retaining native tissue, but long-term durability is unknown. Methods All patients who underwent PVr from 2010 to 2018 for PR resulting from prior PV intervention were included. A control cohort included patients who underwent PVR during the same period for the same indications. Time-related outcomes including freedom from right ventricular outflow tract reintervention, moderate or greater PR, and a maximum Doppler gradient ≥36 mm Hg were compared. Approved as IRB-65340. Results The study included 33 and 151 patients who underwent PVr and PVR, respectively, 72% (132/184) with tetralogy of Fallot. Patients were followed for a median of 9.0 years (6.4-11.5) and 7.7 years (5.4-9.9), respectively ( P = .041). Estimated freedom from reintervention 5 and 10 years after discharge was 97% (80-100) and 89% (69-96) after PVr and 96% (92-99) and 79% (67-87) after PVR. On Cox regression analysis adjusted for age or weight at the time of surgery, and on multivariable Cox regression, PVr was associated with significantly longer freedom from reintervention and valve dysfunction than PVR. Conclusions Pulmonary valve repair was associated with longer freedom from valve dysfunction and reintervention than PVR, particularly in pediatric patients. Lifetime management should be considered at original repair, with an effort to maintain native tissue for potential future PVr.
Experiencing weight stigma during childbirth increases the odds of cesarean birth
Authors: Schwenk Regula A. , Wyss Carmen , Aubry Evelyne M. 
Published: February 2025

Abstract

Background
Weight-biased clinical practices and institutional characteristics can have a wide impact on the quality of care provided to women with obesity. This may substantially increase their risks for poor birth outcomes. The current study assessed experienced weight stigma by women during childbirth in maternity care settings in Switzerland. We aimed to identify frequencies, sources, and manifestations of weight-related stigmatization, hypothesizing that such stigma impacts birth outcomes, specifically cesarean birth (CB).

Methods
Data from a nationwide cross-sectional online survey was used to investigate the frequencies, sources, and manifestations of experienced weight stigma during childbirth. Binomial logistic regression was applied to predict CB from experienced weight stigma. Mediation analysis assessed the role of experienced weight stigma in the association between body mass index (BMI) and CB.

Results
In a total of 1352 women who gave birth in the last five years, women with obesity (BMI ≥ 30 kg/m2) experienced weight stigma more often than their peers with healthy weight (BMI 18.5–24.9 kg/m2). Obstetricians were identified as a major source of weight stigma, accounting for 77.8% of stigmatization experienced by women, compared to stigmatization perceived from nurses (21.7%) and midwives (23.8%). Overall, weight stigma was mostly experienced in the form of dismissive or critical comments towards a woman’s figure or weight. Significantly more women with obesity indicated being blamed for weight-related risks during childbirth than their healthy-weighted peers (χ²(2) = 22.2, P < 0.001). An increase in the frequency of experienced weight stigma was related to higher odds of intrapartum CB ([aOR], 1.08; 95% CI, 1.02,1.15; P < 0.05), and it partially mediated the relationship between increased pre-pregnancy BMI and CB (b = 0.07, SE = 0.029; P < 0.05).

Conclusion
Women with obesity reported the highest proportion of weight stigmatization during childbirth, experiencing stigma more frequently than women without obesity. This increased frequency of weight stigma was associated with higher odds of CB. Raising awareness among healthcare providers and reducing potential biases and stigmatization may improve care quality and health outcomes for women with obesity.
Gender-based variations in surgical management of colorectal liver metastases: comprehensive analysis
Authors: Koch Pia F. , Ludwig Kristina , Hillebrandt Karl H. , Freitag Hannes , Blank Moritz , Knitter Sebastian , Modest Dominik Paul , Krenzien Felix , Lurje Georg , Schöning Wenzel , Pratschke Johann , Sauer Igor M. , Moosburner Simon , Raschzok Nathanael 
Published: February 2025

Abstract

Background
Colorectal cancer with liver metastasis affects both men and women. However, therapeutic strategies and long-term outcomes could be influenced by patients’ sex, due to variations in tumour biology, lifestyle, and dietary habits. By conducting a comprehensive comparative analysis, this study aims to detail differences in tumour characteristics, postoperative complications, recurrence rates, and survival outcomes between sexes.

Methods
Single-centre retrospective analysis between 2010 and 2022 of all patients undergoing liver surgery for colorectal liver metastases (CRLM) at the Department of Surgery, Charité– Universitätsmedizin Berlin. Patients were stratified by sex. Statistical analysis was performed using RV4.2.

Results
We analysed 642 patients who underwent hepatic resections for CRLM. Baseline patient characteristics were comparable between sexes: However, significant differences (p < 0.001) were noted in body mass index (BMI), with females exhibiting lower BMIs (median BMI in females: 23.7 kg/m² vs. males: 26.5 kg/m²). Primary tumour locations varied significantly (p = 0.008), with females presenting more sigmoid colon tumours (37%), while males predominantly had rectal tumours (35%). RAS mutation rates were higher in females (54%) than males (34%, p = 0.005). A higher prevalence of bilobar metastases were evident in men (62%, p = 0.011), yet surgical techniques and complications showed comparable distributions. The time for resection was longer in males (median 304 min vs. 290 min in females); however, conversion to open surgery took place more often in females (5.2% vs. 2.3% in males). Postoperative complications and survival rates showed no significant differences by patients’ sex.

Conclusion
Distinct sex-related patterns in tumour characteristics and postoperative outcomes in patients with CRLM were observed, emphasizing the need for further investigations to understand and address gender-based disparities for more personalized clinical management in the future.

Trial registration
This research was conducted with ethical approval from the relevant institutional review board Ethikkommission der Charité– Universitätsmedizin Berlin’ (reference numbers EA2/006/16 and EA4/084/17). No other registration applied.