bluuebunny/crossref_metadata_2025_split huggingface dataset:
Privacy‐preserving and fine‐grained data sharing for resource‐constrained healthcare CPS devices
Authors: Bao Yangyang , Qiu Weidong , Cheng Xiaochun 
Published: December 2022

AbstractMedical cyber‐physical systems (CPS) provide the possibility for real‐time health monitoring of patients and flexible diagnostic services based on expert systems by collaboratively integrating and connecting various physical devices including sensors, terminals, and cloud infrastructure. However, the ubiquitous security threats in cyberspace have raised concerns about data security and user privacy. Although related works propose to protect data security and user privacy with cryptographic protocols, their heavy computational and storage overheads incur performance and battery life challenges for resource‐constrained devices in the healthcare CPS. This article proposes an energy‐saving and privacy‐preserving data sharing (ESPPDS) scheme to address the challenge. ESPPDS inherits the anonymous fine‐grained access control from attribute‐based encryption (ABE) while protecting data integrity and supporting efficient user revocation. We also eliminate the repetitive computations of ciphertext components by utilizing the online/ offline encryption technology, and design a subtle and secure trick to delegate the decryption operations to the edge device, thereby reducing the computational overheads of the resource‐constrained devices. We then show the security proof, and discuss the construction in the untrusted/ compromised server setting. The comparison and experiment indicate that ESPPDS is practical and more efficient than related schemes.
Children's education and parental support in Jewi Refugee Camp, Ethiopia: Unraveling the challenges
Authors: Demissie Eyueil Abate , Boru Ambissa Kenea 
Published: December 2022

AbstractObjectiveIn this study, we examined the situation of parents and caregivers of the refugee children in Jewi refugee camp with the aim of understanding the roles they play in the education of the children.BackgroundEffective educational interventions benefit from parental engagement. This may be particularly the case for refugee children, who typically have had several traumatic experiences during the departure from their home country, while traveling to safer places, and then on arrival to a refugee camp.MethodsA qualitative single case study approach was used to investigate this issue. Refugee primary school students, teachers, school principals, parents, and camp administrators were used as data sources. Individual and group interviews, observation, and document analysis were used to collect the data. Interpretive and narrative approaches were used for data analysis.ResultThe results of the study indicate that parental support for the learning of refugee children was low. The effort schools make to help parents, who themselves have experienced traumatic situations, engage in their children's education was found to be equally low.ConclusionThere was a low level of awareness regarding the value of education, mainly because individuals had endured long periods of war in South Sudan, during which education was devalued and the educational infrastructure was devastated. Lack of awareness on children's right to education is expressed in failure to treat adopted children as equal to biological children. As a result, in this study, parents' engagement in the education of children was low.ImplicationThere is a need to maximize local and international support to refugees to fulfill the basic needs of refugee children and their caregivers. Schools in refugee camps are responsible not only for providing education to students; their work should extend to providing supportive services to parents/guardians in their parenting practices at home. In addition, there should be continued effort to reunite children who are separated from their parents; implement comprehensive parenting strategies; and develop parent education programs.
Social sports in an aging society: Exercising, recreation and rehabilitation for the elderly
Authors: He Huagang , Yan Jianhua , Li Junhui 
Published: December 2022

AimThis paper analyzes the adaptive changes that take place in mature and elderly women with different track records in social sports in order to develop health and rehabilitation techniques based on personalized and groupwise approaches.MethodsThis longitudinal study was conducted between 2009 and 2019 in Zhengzhou, China. The sample consisted of 24 mature and elderly women (45–65 years old) in the experimental group (regular social sports) and 40 women of the same age who did not exercise (control group). The experimental group received physiotherapy twice a week. The sessions were scheduled for 10 a.m. and lasted for 3 h. The functional status of cardiovascular system parameters (blood pressure, heart rate) was measured. In addition, the physical working capacity (PWC 150), as well as the coefficient of body adaptation to stress and the Robinson index (the amount of oxygen required by the human body to function) were estimated.ResultsWomen from the experimental group maintained stable coefficients of adaptation during all 10 years over which the study was conducted. Women with a long track record (up to 10 years) revealed a slight increase in the body's functional capacity (P ≤ 0.05 with control). More than 50% of the women in the experimental group had cardiovascular measurements within or above the normal range, whereas the opposite was true in the control group.ConclusionsThe longitudinal study revealed upward trends of physical working capacity indicators, which can slow down involutional changes in the body. In some cases, the body's functional capacity may be improved. Geriatr Gerontol Int 2023; 23: 98–102.
18F‐FDG PET/CT imaging for haemophilic arthropathy compared with clinical, radiological and power Doppler sonographic characteristics of 20 haemophilia patients
Authors: Li Tsung‐Ying , Lin Li‐Fan , Pan Ru‐Yu , Cheng Shin‐Nan , Wu Yung‐Tsan , Chen Liang‐Cheng , Chen Yeu‐Chin 
Published: December 2022

AbstractIntroduction and objectivesRepeated joint bleeding in haemophilia patients may lead to haemophilic arthropathy with marked inflammation and synovitis. This study investigated the potential of 18F‐fluorodeoxyglucose positron emission tomography‐computed tomography (18F‐FDG PET/CT) as a novel diagnostic method for haemophilic arthropathy.Materials and methodsWe recruited 20 adult haemophilia patients who reported history of hemarthroses in the shoulder, elbow, hip, knee, or ankle joints. All joints were assessed by power Doppler ultrasonography and radiography, and graded by hyperaemia score and Pettersson score, respectively. Joint pain was evaluated by visual analogue score (VAS). Range of motion (ROM), Haemophilia Joint Health Score (HJHS) and annual joint bleeding rate (AJBR) were recorded. Finally, all participants had whole‐body 18F‐FDG PET/CT, and maximum standardized uptake value (SUVmax) of the joints being studied was measured.ResultsThirteen patients had severe haemophilia, and seven had moderate haemophilia. The mean age was 36 years. PET SUVmax showed significant correlations with VAS, ROM, Pettersson score, hyperaemia score, HJHS score and AJBR in all large joints except hip. Joints with pain, hyperaemia and radiographic changes were found to have higher SUVmax than those without these features. Using Youden's index, the optimal cut‐off value for early radiographical arthropathy was found to be between 1.9 and 2.0.ConclusionOur study indicates that 18F‐FDG PET/CT imaging correlated well with various conventional diagnostic techniques. It also demonstrated high sensitivity and specificity for early radiographic arthropathy. 18F‐FDG PET/CT imaging may quantitatively evaluate disease activity of most large joints in a single examination and help detect early haemophilic arthropathy.
Adding value to learning and development through CILIP accreditation: The NHS knowledge for healthcare learning academy
Authors: Gilroy Dominic , Young Gil 
Published: December 2022

AbstractNHS knowledge and library staff are a highly specialist workforce delivering an economic benefit of £77 million per annum to the health service in England. To achieve their full potential and meet the changing needs of the NHS, it is vital that the workforce remains up to date through the continuing development of their skills, knowledge, and behaviours. This article outlines the work of Health Education England to gain Chartered Institute of Library and Information Professionals (CILIP—The Library and Information Association) quality accreditation for the short course offers delivered through the NHS Knowledge for Healthcare Learning Academy. It summarises the benefits of this accreditation for Health Education England, for employers, and for knowledge and library staff participating in the short courses. Learning points from the experience of the accreditation process are described and shared.
A MULTILAYER VIEW OF SYSTEMIC IMPORTANCE AND AGGREGATE FLUCTUATIONS
Authors: Tzavellas Hector 
Published: December 2022

AbstractEconomic systems are composed of multiple interrelated groups of agents and with multiple sources of network externalities present. This can give rise to novel systemic risks. We propose a multilayer model to understand this phenomenon. The model features complementary or substitutionary actions of agents active in multiple groups and extends the network concepts of systemic importance and microinduced aggregate fluctuations to their multigroup counterparts. The multilayer allows for the propagation of shocks through both intra‐ and interlayer margins. The interlayer margin can be large enough to induce a reordering of systemic importance indicators as compared to singular group considerations, and produce volatility levels that are larger than economies consisting of a single group of agents.
Mechanism of heat‐induced thinning of thick egg white in weak alkaline condition: molecular aggregation, functional and structure properties analysis
Authors: Liu Lan , Wu Yongyan , Duan Wenshan , Song Hongbo , Geng Fang , Wang Jinqiu , Huang Qun , Wei Shaofeng 
Published: December 2022

SummaryThe thinning of thick egg white (KEW) was simulated by weak alkaline (pH 10.0) combined with mild heat (50 °C) treatment. The molecular aggregation, functional and structural characteristics changes in simulated KEW thinning process were comprehensively studied. It was found that KEW molecule entered “molten pellet (MG)” state with decline of apparent viscosity of KEW. At this time, particle size increased by 40.9%, surface hydrophobicity and solubility declined 11.3% and 8.9%, respectively. However, with more mild heating time, KEW structure gradually unfolded, ovomucin (OVM) degraded, particle size diminished significantly. Surface hydrophobicity and solubility increased 6.6% and 19.7%, respectively. Functional properties indicated that thermal gel of KEW gradually became soft and tough, water holding capacity (WHC) advanced by 10%, emulsifying property significantly improved by 40%. Moreover, correlation analysis indicated that tertiary structure was correlated with particle size (P < 0.01), secondary structure related to hardness and WHC (P < 0.05). Through the results of SDS‐PAGE and comparison with KEW simple mild heating, it was concluded that rise of pH was intrinsic driving force of KEW thinning. Therefore, this study provided a new insight for revealing the thinning mechanism of KEW and a scientific basis for its industrial application.
Attitude toward care of the dying and practice of peaceful end‐of‐life care in community hospitals in China
Authors: Li Xia , Kongsuwan Waraporn , Yodchai Kantaporn 
Published: December 2022

AbstractAimTo evaluate nurses’ attitude toward caring for dying patients, their practice of peaceful end‐of‐life care in community hospitals, and the association between these two variables.BackgroundCommunity hospitals play an important role in the peaceful end‐of‐life care. For nurses, one of the key points of offering high‐level care is to improve attitude. However, there are very few studies exploring how the attitude of nurses toward caring for dying patients relates to the practice of peaceful end‐of‐life care in community hospitals across China.MethodsA total of 363 questionnaires were included in this study. Simple random sampling was used to recruit participants from six community hospitals in China. A new instrument, Nurses’ Practice of Peaceful End‐of‐Life Care Instrument (NP‐PECI), was developed according to the Theory of Peaceful End of Life to assess the practice of nurses. Besides, Frommelt Attitudes toward Care of the Dying (FATCOD) was adopted to assess nurses for their attitude toward caring for dying patients.ResultsThe nurses’ attitude toward caring for dying patients showed a significant positive correlation with their practice of peaceful end‐of‐life care statistically (r = 0.175, p < 0.01).ConclusionFor community nurses, it is necessary to improve the attitude of nurses toward the practice of caring for dying patients, thus enhancing the outcome of peaceful end‐of‐life care.Implications for nursing practiceThe Theory of Peaceful End of Life provides a theoretical framework and guideline on the practice of clinical nursing for quality control of peaceful end‐of‐life care, which is significant for improving the palliative care system. In the future, it is worth developing programs based on the Theory of Peaceful End of Life.Implications for nursing policyFor healthcare policy makers, this study can be helpful to refine the existing palliative care support policies and strategies targeted at community hospitals and their nurses.
Preparedness of Australian and British nurses and midwives about domestic violence and abuse
Authors: Ali Parveen , Ayyaz Rida , McGarry Julie , Younas Ahtisham , Watson Roger , East Leah 
Published: December 2022

AbstractBackgroundDomestic violence and abuse (DVA) is a major health problem that affects individuals across the world. Nurses, midwives and healthcare providers need to be confident and competent in identifying and responding to DVA.AimsTo measure current levels of knowledge, opinions and preparedness towards DVA and how it is managed by registered nurses and midwives residing in Australia and the UK.MethodsA cross‐sectional study design was used. Data were collected using the Physician Readiness to Manage Intimate Partner Violence Survey (PREMIS) measuring the perceived preparation and knowledge, actual knowledge, opinions and practice issues. Australian data were collected in 2018 and UK data were collected in 2017–2018. Descriptive and inferential statistics were used to analyse the data and differences in knowledge and attitudes of British and Australian nurses.FindingsNurses and midwives (n = 368; 130 from Australia; 238 from the UK) responded to the survey. Minimal previous DVA training was reported by the participants. Participants had minimal knowledge about DVA, though had a positive attitude towards engaging with women experiencing DVA.DiscussionMost participants felt unprepared to ask relevant questions about DVA and had inadequate knowledge about available resources. Australian participants scored better than British participants; however, the mean difference in all aspects remained statistically insignificant.ConclusionAustralian and British nurses and midwives have a positive attitude towards women experiencing DVA; however, the knowledge and skills to support women experiencing DVA are limited.Implications for nursing policyNursing institutions should develop strategic policies regarding mandatory preparation and training of nurses for domestic violence assessment and management.
Effect of COVID‐19 vaccine on menstrual experience among females in six Arab countries: A cross sectional study
Authors: Matar Sajeda Ghassan , Nourelden Anas Zakarya , Assar Ahmed , Bahbah Eshak I. , Alfryjat Areej M. , Hasabo Elfatih A. , Matar Suzan A. , Bishtawi Shatha Nizar , Alhoubani Mays , Yahia Ahmad Bassam , Ragab Khaled Mohamed , Salameh Lina Mohammad , Salameh Lana Saif Eddin , Zaazouee Mohamed Sayed , Al‐kafarna Mohammed , Elshanbary Alaa Ahmed , Almadhoon Hossam Waleed , Bakdash Shahed Toulaq , Adam Ola Awad Babiker , Malih Abdelkader Nabeel , Habash Shimaa Abo elfotoh , Basiouny Rakia Mohamed Taha , Ahmad Afaf , Hamid Raghda Mohammed Ahmed , Habib Balsam Younan , Elokl Dalia Nasr , Abdalraheem Hiba Hatim , Atia Esraa Adel , Yousif Nazik Ibrahim Ahmed , Al‐Ali Fida Hussien , Alshaer Israa Mohammed , Abdulali Fatima Elsidieg , Ayesh Hadil Abu , Jabari Anwar Yousef , Egzait Raneem Ahmed , Munshar Nameer Amer Abu , Alkhraibat Aseel Ahmad , ibreerah Aisha Hasan , Basheti Iman A. 
Published: December 2022

AbstractBackgroundThere have been varying reports on the potential occurrence and severity of changes to menstruation including the median cycle length, days of bleeding, bleeding heaviness, and menstrual pain, following receipt of COVID‐19 vaccinations. We aimed to assess potential postvaccination menstrual changes in women residing in the Middle East.MethodsWe implemented a cross‐sectional online survey‐based study. Data about the participants' demographic characteristics, menstruation experience, and vaccination status were collected and analyzed among six Arab countries.ResultsAmong 4942 menstruating females included in this study, females who had received one or more doses of COVID‐19 vaccination reported a higher frequency of back pain, nausea, tiredness, pelvic pain with periods, unprescribed analgesics use, and passage of loose stools. They also reported higher scores describing average and worst menstrual pain. Fully vaccinated females reported heavier flow and more days of bleeding.ConclusionOur findings indicate that COVID‐19 vaccine may have an effect on menstruation in terms of menstrual pain and bleeding heaviness. The evidence needs to be further investigated in longitudinal studies.
Dietary calcium intake was related to the onset of pre‐eclampsia: The TMM BirThree Cohort Study
Authors: Ohseto Hisashi , Ishikuro Mami , Obara Taku , Murakami Keiko , Onuma Tomomi , Noda Aoi , Takahashi Ippei , Matsuzaki Fumiko , Ueno Fumihiko , Iwama Noriyuki , Kikuya Masahiro , Metoki Hirohito , Sugawara Junichi , Kuriyama Shinichi 
Published: December 2022

AbstractThis study aimed to explore the relationship between dietary electrolyte intake and the prevalence of hypertensive disorders of pregnancy (HDP) subtypes. Our analysis included 19 914 pregnant women from the Tohoku Medical Megabank Project Birth and Three‐Generation Cohort Study. A food frequency questionnaire was used to estimate dietary calcium, potassium, sodium, and magnesium intakes. HDP was determined based on the medical records during regular antenatal care. Logistic regression analysis assessed the relationship between dietary electrolytes intake quintiles, and HDP subtypes with adjustment for basic characteristics. Dietary electrolyte intakes were applied for the prediction model. Of the cohort, 547 participants delivered with pre‐eclampsia (PE), 278 with superimposed PE (SP), and 896 with gestational hypertension (GH). PE was associated with low crude calcium intake (odds ratio of the first quintile [<251 mg/day] to the fifth quintile [>623 mg/day] and 95% confidence interval, 1.31 [1.00–1.70]) and P for trend was .02. SP was not associated with any nutritional intake; however, the combined outcome of PE and SP was related to low crude calcium and potassium and energy‐adjusted calcium, potassium, and magnesium intakes (P for trend, .01, .048, .02, .04, and .02, respectively). The same tendency was observed for GH. A prediction model that included crude calcium and potassium intakes performed better than a model without them. In conclusion, low dietary calcium, potassium, and magnesium were associated with higher HDP subtypes prevalence. The prediction model implied that crude calcium and potassium intakes might play a critical role in PE and SP pathogenesis.
HDAC6 regulates human erythroid differentiation through modulation of JAK2 signalling
Authors: Vong Pascal , Messaoudi Kahia , Jankovsky Nicolas , Gomilla Cathy , Demont Yohann , Caulier Alexis , Jedraszak Guillaume , Demagny Julien , Djordjevic Stefan , Boyer Thomas , Marolleau Jean Pierre , Rochette Jacques , Ouled‐Haddou Hakim , Garçon Loïc 
Published: December 2022

AbstractAmong histone deacetylases, HDAC6 is unusual in its cytoplasmic localization. Its inhibition leads to hyperacetylation of non‐histone proteins, inhibiting cell cycle, proliferation and apoptosis. Ricolinostat (ACY‐1215) is a selective inhibitor of the histone deacetylase HDAC6 with proven efficacy in the treatment of malignant diseases, but anaemia is one of the most frequent side effects. We investigated here the underlying mechanisms of this erythroid toxicity. We first confirmed that HDAC6 was strongly expressed at both RNA and protein levels in CD34+‐cells‐derived erythroid progenitors. ACY‐1215 exposure on CD34+‐cells driven in vitro towards the erythroid lineage led to a decreased cell count, an increased apoptotic rate and a delayed erythroid differentiation with accumulation of weakly hemoglobinized immature erythroblasts. This was accompanied by drastic changes in the transcriptomic profile of primary cells as shown by RNAseq. In erythroid cells, ACY‐1215 and shRNA‐mediated HDAC6 knockdown inhibited the EPO‐dependent JAK2 phosphorylation. Using acetylome, we identified 14‐3‐3ζ, known to interact directly with the JAK2 negative regulator LNK, as a potential HDAC6 target in erythroid cells. We confirmed that 14‐3‐3ζ was hyperacetylated after ACY‐1215 exposure, which decreased the 14‐3‐3ζ/LNK interaction while increased LNK ability to interact with JAK2. Thus, in addition to its previously described role in the enucleation of mouse fetal liver erythroblasts, we identified here a new mechanism of HDAC6‐dependent control of erythropoiesis through 14‐3‐3ζ acetylation level, LNK availability and finally JAK2 activation in response to EPO, which is crucial downstream of EPO‐R activation for human erythroid cell survival, proliferation and differentiation.