bluuebunny/crossref_metadata_2025_split huggingface dataset:
Conservation, Animal Wellbeing, and Indigenous Participation at an Elephant Sanctuary in Mondulkiri, Cambodia
Authors: Kopnina Helen , Baker Liv 
Published: May 2023

Abstract
This article focuses on the intersection of indigenous peoples, conservation, and elephant wellbeing in Cambodia. While social justice advocates emphasize the human cost of conservation in human-animal conflicts, those concerned with animal protection and rights have problematized the treatment of elephants. This critique stems from evidence that the human relationship to elephants, captive and wild, remains largely utilitarian or exploitive. In Cambodia, there is a record of wild Asian elephants coexisting with local communities, but more so a long history of elephants used for labor. This article discusses the possible areas of reconciliation between human and Asian elephant interests at a Mondulkiri elephant sanctuary in Cambodia, suggesting potential paths toward win-win scenarios for the local and indigenous people, as well as for the elephants and their habitats.
Sulla sua passione per l’ascolto (Περὶ τῆς αὐτοῦ φιληκοΐας): l’orazione 19 di Dione di Prusa
Authors: Bernardi Gianluigi 
Published: May 2023

Abstract
A short text by Dio of Prusa is analyzed, regarding the orator’s personal judgment on kitharōidia and the relationship it has with sophistic art and tragic literature as means of cultural dissemination. The article aims to propose a plausible interpretation of the text, on the one hand by examining the (few) data provided by critical studies, and on the other, especially, by making use of the author’s main research work, carried out by collecting all the passages of musical interest and ‘sound events’ contained in Dio’s speeches.
Land–Atmosphere Interactions Partially Offset the Accelerated Tibetan Plateau Water Cycle through Dynamical Processes
Authors: Sun Jing , Yang Kun , Yu Yan , Lu Hui , Lin Yanluan 
Published: May 2023

Abstract
The Tibetan Plateau (TP) has become wetter and warmer during the past four decades, which leads to an adjustment in the surface energy budget, characterized by enhanced surface latent heat and weakened surface sensible heat. However, the impacts of these surface energy changes on climate are unclear. In this study, we investigate the atmospheric response to the altered surface energy budget in the monsoon season over the TP using regional climate simulations. The inhibited surface sensible heating weakens the thermal effect of the TP, which further suppresses low-level convergence and upper-level divergence, thereby weakening the water vapor flux convergence over the plateau. The weakening of low-level air humidity by this dynamical response exceeds the supply from the enhanced surface evaporation, causing decreased precipitation (decreasing more in the wet eastern plateau and less in the dry west). Further analyses show that the precipitation frequency increases mainly for light precipitation while decreasing for heavy precipitation. It is thus demonstrated that on the TP, land surface energy–atmosphere interactions can mitigate the rate of precipitation increase, suppress the increase in frequency of heavy precipitation, and weaken the east–west contrast in precipitation amount, through a dynamical mechanism. Overall, land–atmosphere interactions on the TP exert negative feedback to partially offset the accelerated plateau water cycle under a changing climate.
Determination of in vitro stability of routine haematinics tests using EFLM standards and the CRESS checklist
Authors: Williams Robert D , Duff Christopher J , Yates Alexandra 
Published: May 2023

Background Laboratories should be aware of the stability of the analytes they are testing in order to avoid incorrect reporting and patient management. Stability studies are difficult to interpret and reproduce, with little guidance on how to determine appropriate clinical cut off values. Here we describe a standardised approach to determining stability for routine haematinics tests using published EFLM guidelines. Methods The haematinics panel at UHNM contains vitamin B12, folate, ferritin, iron and transferrin. Blood tubes included were serum separator tubes, gel-free serum and lithium-heparin plasma. Conditions tested were room temperature, 2–8°C and −20°C. For each condition and tube, three samples were analysed in duplicate at 0, 24, 48, 72, 96 and 120 h using the Siemens Atellica platform. Results The percentage difference was calculated for each respective blood tube and storage condition, in addition to individual analyte maximum permissible instability scores. The majority of analytes for all blood tubes were stable for 5 days or more when stored at 4–8°C and −20°C. Ferritin (excluding gel-free), iron and transferrin further showed stability >5 days when stored at room temperature. However, vitamin B12 and folate demonstrated poor stability data for all tube types tested. Conclusions Here we describe a stability study for the haematinics panel on the Siemens Atellica platform using the standardised EFLM Checklist for Reporting Stability Studies (CRESS). The checklist was used in order to promote a standardised and transferable scientific approach to what has previously been lacking in the literature when performing stability experiments.
Discharge destinations for young people with a first episode of psychosis after attending an early intervention for psychosis service
Authors: O’Donoghue Brian , Thompson Andrew , McGorry Patrick , Brown Ellie 
Published: May 2023

Objective: Early intervention for psychosis services result in superior outcomes in the domains of symptomatic and functional recovery, hospitalisation and employment compared to standard services; however, the optimal duration of care with these services is unknown. Knowledge on the discharge destinations, specifically the proportion discharged to high- and low-intensity services, could provide insights into the proportion of who may require a longer tenure of care. This study aimed to determine (1) the discharge destinations from early intervention for psychosis services and (2) baseline and intra-episode factors associated with discharge to the secondary care/adult mental health service. Methodology: This study was conducted at the Early Psychosis Prevention and Intervention Centre in Melbourne and included all young people treated by the service with a first episode of psychosis over a 6-year period. Discharge destinations were categorised according to high-intensity services, namely, secondary mental health care, or lower intensity services, such as private practitioners or primary care. Results: A total of 1101 young people with a first episode of psychosis were included in the study, of whom 58.8% were male and the median age was 20.0 years (interquartile range: 17–22). After a median of 95.4 weeks (interquartile range: 66.7–105.7), 36.6% were discharged to the adult mental health services, which was associated with being not in employment, education or training at presentation (odds ratio = 1.71, 95% confidence interval [1.23, 2.37]); experiencing a relapse (odds ratio = 1.76, 95% confidence interval [1.24, 2.49]); and being admitted to a mental health unit (odds ratio = 3.98, 95% confidence interval [2.61, 6.09]). Young people who lived with their parents were less likely to be discharged to secondary care services (odds ratio = 0.52, 95% confidence interval [0.37, 0.73]), as were those who were achieving symptomatic remission within 12 weeks (odds ratio = 0.60, 95% confidence interval [0.43, 0.83]). Migrant status and the duration of untreated psychosis were not associated with discharge destination. Conclusion: These findings indicate that there is a sizable, identifiable minority who may benefit from a longer episode of care with early intervention for psychosis services.
Drug transfer during intimate moments: A key issue in doping control that can be documented by hair tests of the athlete and the partner
Authors: Kintz Pascal 
Published: May 2023

The presence of a prohibited substance or its metabolites or its markers in an athlete's sample constitutes the more frequent anti-doping rules violation. In the world anti-doping code, it is indicated (point 10.5) that if someone establishes in an individual case that the athlete bears no fault or negligence, then the otherwise applicable period of ineligibility shall be eliminated. The conditions that have to be met to fix the no fault or negligence evidence are described in several other points of the code. The following two points are of paramount importance: 1. the athlete or his/her legal representative must present verified circumstances of contamination and the source of contamination must be identified; and  2. there must be verified claims by the athlete about the fact that he/she did not knowingly take the prohibited substance, i.e., that the violation was not intentional. In recent years, several cases of contamination involving drug transfer during intimate moments have been reported. This later situation was first reported in 2009 with the Richard Gasquet case. Since that time, several athletes have been allowed to return to competition with no charge based on strong evidence that the source of contamination was drug transfer during intimate moments. As some of these cases are public and because the author performed hair tests for the majority of the international athletes involved in such procedures, the strategy of the defence and the scientific bases of discussion are reviewed in this article.
Use of immune checkpoint inhibitors in the treatment of patients with cancer and preexisting autoimmune disease: An integrative review
Authors: Freitas Julia de Almeida Santos , Bendicho Maria Teresita , Júnior Aníbal de Freitas Santos 
Published: May 2023

Introduction Checkpoint inhibitors (PCI) have reached an important place in the pharmaceutical market in the treatment of various types of cancer. However, due to immune-related adverse events (IRAE) to the treatment, patients with preexisting autoimmune diseases (PAD) are excluded from clinical studies, leading to a large gap in knowledge on this topic. This study aims to discuss the use of PCI in the patients with cancer and PAD by an integrative review. Methods For this integrative review we carried out research from 2013 to 2022 using database platforms for observational studies reporting data from safety and efficacy of PCI in patients with cancer and PAD. Results The search resulted in 161 articles and after applying the exclusion criteria, 15 clinical studies that adopted a retrospective observational design were selected and analyzed. The age range of patients was 54–71 years, with 19–68% male. The proportion of patients clinically active or receiving immunosuppressants who were initiated on PCI ranged from 0% to 57% and 14% to 73%, respectively. The mean reported follow-up time ranged from 8.0 to 16.8 months. The occurrence of an outbreak or the new IRAE had an average of 32.6%. Conclusion IRAE are frequent in patients who use PCI and have cancer and PAD, carrying discontinuation of therapy. However, the multidisciplinary team needs to be aligned to manage these situations in the best way.
The Role of Fractional Exhaled Nitric Oxide in Diagnosing Asthmatic Type 2 Chronic Rhinosinusitis With Nasal Polyps
Authors: Park Jin-A , Cha Hyunkyung , Yang Seung Koo , Ryu Hyun Tae , Kim Do Won , Hong Seung-No , Yang Min Suk , Kim Dae Woo 
Published: May 2023

Background Fractional exhaled nitric oxide (FeNO) is useful in the management of asthma and predicting the efficacy of standard corticosteroids and biologics. However, the diagnostic value of FeNO in asthmatic chronic rhinosinusitis with nasal polyps (CRSwNP) remains unclear. Objective We assessed FeNO levels in patients with CRSwNP and evaluated the diagnostic value of FeNO for screening type 2 CRSwNP (T2-CRSwNP) with asthma. Methods We enrolled 94 patients who were diagnosed with CRSwNP and underwent functional endoscopic sinus surgery. FeNO levels, the blood eosinophil percentage, total IgE, spirometry tests (FEV1/FVC), Lund–Mackay CT score, and percentage of patients with comorbid asthma were compared among CRSwNP subgroups. Spearman rank correlation test was used to assess the degree of association between variables. ROC curve analysis was conducted to evaluate the diagnostic capability to differentiate T2-CRSwNP based on clinical and histological classifications. Results FeNO levels and the blood eosinophil percentage were significantly higher in patients with T2-CRSwNP(h) based on histological data ( P < .05). FeNO was correlated with the blood eosinophil percentage ( r = 0.420, P < .001) and FEV1/FVC ( r = −0.324, P = .001). A FeNO level of 27 ppb had a good ability to discriminate patients with asthmatic T2-CRSwNP(h) (AUC = 0.848; 95% CI = 0.7602-0.9361; sensitivity = 90.9%; specificity = 63.9%). The optimal cutoff values for FeNO and the blood eosinophil percentage for diagnosing asthmatic T2-CRSwNP(h) were 68 ppb and 5.6% (sensitivity = 95.5%; specificity = 86.1%; AUC = 0.931; 95% CI = 0.8832-0.9791). In the diagnosis of severe T2-CRSwNP(c) based on clinical data, a FeNO level of 36 ppb showed the highest AUC (0.816; 95% CI = 0.7173-0.914; sensitivity = 72.7%; specificity = 79.2%). Conclusion FeNO is a useful marker for screening asthmatic T2-CRSwNP even prior to biopsy or asthma evaluation and may assist in selecting a proper treatment.
A case of feline gastrointestinal eosinophilic sclerosing fibroplasia associated with fungal colonisation: endoscopic features, treatment and follow-up
Authors: Martineau Michael , Tilmant Cyril , Risco Castillo Veronica , Guillot Jacques , Reyes-Gomez Edouard , Benchekroun Ghita , Freiche Valerie 
Published: May 2023

Case summary A 5-year-old castrated male domestic shorthair cat presented with a 3-month history of weight loss, chronic diarrhoea and vomiting. Examination revealed a large proximal duodenal lesion eventually diagnosed as feline gastrointestinal eosinophilic sclerosing fibroplasia (FGESF) associated with fungal filaments. Histological examination was performed following endoscopic biopsy. Direct examination and mycological culture of the duodenal biopsies revealed the presence of a siphomycetous fungus, which was further identified as Rhizopus microsporus. Treatment with prednisolone and ciclosporin for 3 months led to complete resolution of the clinical signs and marked improvement of the endoscopic lesions. Specific fungal treatment with amphotericin B was poorly tolerated. Relevance and novel information To the best of our knowledge, this is the first report of the characterisation of a siphomycetous fungus associated with FGESF lesions, and the first endoscopic description and diagnosis of FGESF without surgical biopsies. We hypothesise that the presence of R microsporus occurred because of disrupted mucosal integrity.
Support Experiences for Novice Nurses in the Workplace: A Qualitative Analysis
Authors: Najafi Bahareh , Nasiri Ahmad 
Published: May 2023

Introduction Since novice nurses need support at the beginning of their work, knowing workplace support resources can help them to experience fewer challenges at the beginning of their work and improve the quality of patient care. Objective(s) The present qualitative study aimed to explore novice nurses’ experiences of supporting the workplace at the beginning of their work. Design This qualitative study was performed using a content analysis method. Methods This qualitative study was conducted with 14 novice nurse participants using the conventional content analysis method, unstructured in-depth interviews were used to collect data. All data were recorded, transcribed, and analyzed based on the Graneheim and Lundman method. Results Two major categories and four subcategories were extracted during data analysis as follows: (1) An intimate work environment with subcategories of cooperative work atmosphere and empathetic behaviors, (2) Educational support available for improvement contains subcategories conducting orientation courses and holding retraining courses. Conclusion The present study showed that such experiences as an intimate work environment, and educational support help novice nurses to have a supportive workplace and improve their performance. A welcoming and supportive atmosphere should be created for newcomers to ease their anxiety and frustration. Furthermore, they can improve their performance and provide quality care by giving themselves the motivation and spirit of improvement. Relevance to Clinical Practice This research highlights the need for new nurses to have support resources in the work environment, and healthcare managers can improve the quality of care by allocating sufficient support resources to this group of nurses.
Repair of a Reverse HAGL: A 2-Portal Technique
Authors: Goodloe J. Brett , Schwartz Joshua M. , Tagliero Adam J. , Klosterman Emma L. , Brockmeier Stephen F. 
Published: May 2023

Background: Glenohumeral joint stability is reliant on a combination of static and dynamic constraints. Humeral avulsion of the posterior band of the inferior glenohumeral ligament (HAGL) is an exceedingly rare injury. These injuries can be difficult to diagnose and can lead to continued pain, dysfunction, and recurrent instability. There is a paucity of literature regarding surgical management of reverse HAGL lesions. Indications: Many intrasubstance reverse HAGL lesions can be managed nonoperatively with rehabilitation focused on improving shoulder stability. Although the incidence of recurrent instability in patients with reverse HAGL lesions is unknown, the acute detached humeral lesions in athletes are often treated surgically to restore normal shoulder. Technique Description: The patient was placed in a standard beach chair position, and the standard portals were made for a diagnostic shoulder arthroscopy. The anterior portal was the primary viewing portal. Using the initial posterior skin incision, instruments were introduced through the defect from the retracted posterior band of the inferior glenohumeral ligament. Using a combination of the 30° and 70° arthroscope, the HAGL was mobilized from the infraspinatus musculature. Two knotless suture devices (1.8-mm suture anchor, 2.6-mm suture anchor) were used to reduce the reverse HAGL lesion to an anatomical position, and the posterior capsule was closed thereafter. Results: Only case studies and a single case series have been published pertaining to reverse HAGL repair techniques and related outcomes. When diagnosed and treated appropriately, arthroscopic repairs yield promising results with a high percentage of patients returning to prior level of activity or returning to prior participation level in sport. However, outcome data are limited given the rare occurrence of this injury pattern. Discussion/Conclusion: Reverse HAGL pathology can be treated effectively with arthroscopic surgical repair to restore the normal capsular anatomy and prevent recurrent instability and persistent posterior shoulder pain. Using a 2-portal approach with posterior capsular closure is a minimally invasive operation that allows for appropriate management of these rare injuries. Patient Consent Disclosure Statement: The author(s) attests that consent has been obtained from any patient(s) appearing in this publication. If the individual may be identifiable, the author(s) has included a statement of release or other written form of approval from the patient(s) with this submission for publication.
Human Visual Attention Mechanism-Inspired Point-and-Line Stereo Visual Odometry for Environments with Uneven Distributed Features
Authors: Wang Chang , Zhang Jianhua , Zhao Yan , Zhou Youjie , Jiang Jincheng 
Published: May 2023

AbstractVisual odometry is critical in visual simultaneous localization and mapping for robot navigation. However, the pose estimation performance of most current visual odometry algorithms degrades in scenes with unevenly distributed features because dense features occupy excessive weight. Herein, a new human visual attention mechanism for point-and-line stereo visual odometry, which is called point-line-weight-mechanism visual odometry (PLWM-VO), is proposed to describe scene features in a global and balanced manner. A weight-adaptive model based on region partition and region growth is generated for the human visual attention mechanism, where sufficient attention is assigned to position-distinctive objects (sparse features in the environment). Furthermore, the sum of absolute differences algorithm is used to improve the accuracy of initialization for line features. Compared with the state-of-the-art method (ORB-VO), PLWM-VO show a 36.79% reduction in the absolute trajectory error on the Kitti and Euroc datasets. Although the time consumption of PLWM-VO is higher than that of ORB-VO, online test results indicate that PLWM-VO satisfies the real-time demand. The proposed algorithm not only significantly promotes the environmental adaptability of visual odometry, but also quantitatively demonstrates the superiority of the human visual attention mechanism.
Traumatic peripheral nerve injuries: a classification proposal
Authors: Lavorato Andrea , Aruta Gelsomina , De Marco Raffaele , Zeppa Pietro , Titolo Paolo , Colonna Michele Rosario , Galeano Mariarosaria , Costa Alfio Luca , Vincitorio Francesca , Garbossa Diego , Battiston Bruno 
Published: May 2023

Abstract
Background
Peripheral nerve injuries (PNIs) include several conditions in which one or more peripheral nerves are damaged. Trauma is one of the most common causes of PNIs and young people are particularly affected. They have a significant impact on patients’ quality of life and on the healthcare system, while timing and type of surgical treatment are of the utmost importance to guarantee the most favorable functional recovery. To date, several different classifications of PNIs have been proposed, most of them focusing on just one or few aspects of these complex conditions, such as type of injury, anatomic situation, or prognostic factors. Current classifications do not enable us to have a complete view of this pathology, which includes diagnosis, treatment choice, and possible outcomes. This fragmentation sometimes leads to an ambiguous definition of PNIs and the impossibility of exchanging crucial information between different physicians and healthcare structures, which can create confusion in the choice of therapeutic strategies and timing of surgery.

Materials
The authors retrospectively analyzed a group of 24 patients treated in their center and applied a new classification for PNI injuries. They chose (a) five injury-related factors, namely nerve involved, lesion site, nerve type (whether motor, sensory or mixed), surrounding tissues (whether soft tissues were involved or not), and lesion type—whether partial/in continuity or complete. An alphanumeric code was applied to each of these classes, and (b) four prognostic codes, related to age, timing, techniques, and comorbidities.

Results
An alphanumeric code was produced, similar to that used in the AO classification of fractures.

Conclusions
The authors propose this novel classification for PNIs, with the main advantage to allow physicians to easily understand the characteristics of nerve lesions, severity, possibility of spontaneous recovery, onset of early complications, need for surgical treatment, and the best surgical approach.
Level of evidence: according to the Oxford 2011 level of evidence, level 2.