bluuebunny/crossref_metadata_2025_split huggingface dataset:
Propuesta didáctica para un curso de cálculo diferencial para ciencias económico administrativas centrado en el estudiante
Authors: Marín Maldonado Sara L. , Fuentes Uribe I. Xóchitl , Plazola Zamora Laura , Torres Mata Ana 
Published: August 2023

El estilo de vida de los estudiantes y de la sociedad en general ha cambiado mucho en los últimos años debido a diversos factores como la globalización y los cambios tecnológicos. Es de vital importancia cambiar nuestro discurso académico como profesores con el fin de que el estudiante adquiera un aprendizaje significativo. En este trabajo se discute acerca del producto final de un curso de cálculo diferencial a nivel licenciatura, implementada en el primer semestre del área común en el Centro Universitario de Ciencias Económico Administrativas de la Universidad de Guadalajara. El curso está centrado en el estudiante y el concepto de función es el protagonista principal. En el producto final, el estudiante, por medio de la modelación matemática, construye funciones a partir de datos reales con el fin de obtener aprendizajes significativos.
Introducción
Authors: Cuevas Vallejo Carlos Armando 
Published: August 2023

Este año ha sido aciago, desde el inicio de la pandemia de Covid-19, tuvimos la lamentable desaparición de dos grandes maestros y amigos: Eugenio Filloy Y. y François Pluvinage, uno en México y otro en Francia desde entonces hasta día de hoy las noticias de terribles desapariciones no han parado; hoy más que nunca valoramos nuestra existencia y nuestro trabajo como científicos que nos permite refugiarnos en el templo de la ciencia para no caer en desaliento.
El currículo de ambos maestros es muy amplio para resumirlo en esta breve introducción, baste decir que ambos fueron pioneros en el ámbito internacional en el desarrollo de lo que hoy se conoce como matemática educativa, ambos tuvieron que luchar fuertemente por el reconocimiento de esta nueva disciplina que se denomina Matemática Educativa; que como muchos de ustedes saben requiere de un conocimiento matemático sólido, de la sicología del aprendizaje, de la historia del desarrollo conceptual de la ciencia, de la epistemología, de la sociología del aprendizaje y de la informática entre otras; y que por ello representa un gran reto su estudio. No fue sencilla la tarea fue necesario vencer inercias y aclarar a denostaciones de colegas de diversas ciencias y disciplinas, por ello el mejor tributo que podemos brindar a nuestros maestros es la continuación del trabajo científico en matemática educativa.Por esta razón la publicación de revistas científicas es algo muy importante para la comunidad y humanidad, no solo por los logros que artículos anuncian, sino también porque nos alientan a seguir en la investigación y a mostrarles a las futuras generaciones que el trabajo científico es una manera de evidenciar la vida.La revista de este segundo semestre del 2020 contiene tres artículos, dos de ellos se refieren a la terrible enfermedad de SARS CoV-2 o Covid-19 y de sus efectos en la educación matemática y un tercero se refiere al modelo Cuvima aplicado por colegas de Colombia a la enseñanza de la función cuadrática.A nombre del comité editorial reciban nuestro agradecimiento por seguir confiando en nuestra revista y les deseamos una navidad con salud, amor y paz un mejor año 2021.Armando Cuevas-VallejoEditor
Los estudiantes de Cálculo a través de los errores algebraicos
Authors: Díaz Gómez José Luis 
Published: August 2023

Al álgebra se le dedica un tiempo importante de instrucción en el nivel de secundaria y preparatoria. Sin embargo, los estudiantes que ingresan a la universidad tienen dificultades con la comprensión y manejo de conceptos fundamentales relacionados con ella. La presencia de errores algebraicos obstaculiza con frecuencia la articulación exitosa, y resulta por ello imprescindible un adecuado diagnóstico con el propósito de incidir sobre ellos. En este trabajo se presentan los resultados de la aplicación de un examen diagnóstico de álgebra a una muestra de estudiantes de un curso de Cálculo Diferencial que, entre otros, tiene los siguientes propósitos: (a) detectar los errores algebraicos más frecuentes; (b) detectar los temas de álgebra en los cuales los alumnos tienen más dificultades; y (c) hacer un seguimiento del comportamiento de los alumnos a través de su paso por los cursos de Cálculo Diferencial, Cálculo Integral y Ecuaciones Diferenciales.
Mathematics in its relation to other disciplines. Some examples related to economics and physics
Authors: Dorier Jean-Luc 
Published: August 2023

Mathematics is often seen as a very specific subject, either by students, parents, media or even mathematicians themselves. In many contexts, mathematics is feared and seen as a subject for selection, disconnected from interesting applications to real life. Moreover, the structure of teaching institutions, in many cases, makes the collaboration between teachers from different disciplines very difficult. At the same time, mathematics is more and more invisible in everyday life, since high technology tends to hide the mathematics necessary for its creation in sophisticated black boxes. As a result, it is quite a challenge to give an adequate answer to those who, legitimately, wonder what mathematics is useful for.
Our purpose in this paper is to see how mathematics in different curricula is actually connected to other disciplines and to give propositions to make this connection more effi- cient for the benefit of both mathematics and other subjects.
The results presented here emerged from different research works that we lead in relation to physics and economics.
After a short introduction presenting the situation in France.we will give two kinds of examples:
- In the context of French upper secondary scientific education: the use of vectors in physics and the connection between the notions of translatory and rotating movements in physics and the notions of translation and rotation in mathematics.
- In the context of French upper secondary and university education specialised in economics: the use of matrices for linear models of production and the use of functions, and especially of the concept of derivative and its relation to the notion of marginality in eco- nomics.
Our study reveals that, most often, teachers know very little about other subjects, even in relation to their oyen subject. Mathematics teachers do not want to get involved in too specialised applications while physics or economics teachers send their students back to their mathematics teacher for explanations on the use of mathematics in their field. As a result, students are used to seeing mathematics and other subjects as disconnected. This is reinforced by cultural differences, especially visible in the use of vocabulaiy or recipes that create artificial gaps between different disciplines.
Analysis of the Role of Farmer Groups in Increasing the Income of the Community of Jumateguh Village Bunturaja District
Authors: Simamora Sonia , Yusnadi Yusnadi , Machmud Muhammad Takwin 
Published: August 2023

This study aims to explain the role of farmer groups in increasing the income of the people of Jumateguh Village, Banturaja District. The qualitative approach using descriptive methods and data collection techniques including observation, interviews, and documentation. The results shows there are three roles of farmer groups in the Jumateguh village community, namely as a forum for discussion for group members in solving a problem by finding solutions together through discussion forums, secondly as a forum for information for group members in obtaining information from extension agents regarding how to choosing good/superior plant seeds, as well as handling pests and diseases that attack plants, and the third as a production unit, namely providing production facilities and infrastructure such as tanks for spraying pesticides and insecticides on plants and tripe machines to clean grass that disturbs plants.
Ameliorative Effect of Aqueous Crude Extract of the Aerial Parts of Leonurus Cardiaca on Doxorubicin-Induced Cardiovascular Damage in Wistar Rats
Authors: Wellington E. O. , Otobo M. B. , Ogbomade S. J. 
Published: August 2023

This study investigated the ameliorative effect of aqueous crude extract of the aerial parts of Leonurus cardiaca on doxorubicin-induced cardiovascular damage in Wistar rats. Aqueous crude extract of Leonurus cardiaca was prepared based on standard Laboratory condition. A total of 55 male and female rats weighing between 170 ± 15 and 180±15g were used for this study. The rats were grouped into 11 groups of five rats per group. Group 1 and 2 served as normal and negative control rats respectively. Rats in group 3-11 were intraperitoneally administered 18mg/kg of doxorubicin once and were treated with the crude extract at 166, 250, and 500mg/kg for 7, 14, and 21 days. All biochemical, hematological, and histological analyses were carried out based on standard methods. The mean plasma troponin T and I, IL-6 and C-reactive protein concentrations of the negative control were 357.93±0.01 pg/mL, 241.51±0.00 pg/mL, 63.94±0.01 pg/dl, and 41.03±0.01 mg/ml respectively. The plasma troponin T and I, IL-6 and C-reactive protein concentrations treated for 21 days were 270.32±0.01 pg/mL, 217.84±0.01 pg/mL, 42.75±0.01 pg/dl, and 18.03±0.01 mg/ml respectively. The mean MDA, GSH concentrations, GPx, CAT and SOD activities in doxorubicin-induced cardiovascular damage rats, treated with the extract at 500mg/kg were 5.01±0.01mmol/l, 68.46±0.02µg/mg.protein, 70.21±0.01mg/pro.min, 141.62±1.80IU/g, and 19.05±0.02mg/g respectively and were significantly different from those of group 2. Aqueous crude extract of Leonurus cardiaca at 500mg/kg ameliorated the damage induced by doxorubicin on the heart tissues, hence could serve as a novel herbal agent for the treatment of cardiovascular damage.
Genetic Variability, Heritability and Genetic Advance Analysis in Bread Wheat (Triticum aestivum L.) Genotypes
Authors: Chauhan Sugandh , Gupta Anuj , Tyagi Sunil Dutt , Singh Satpal 
Published: August 2023

Wheat (Triticum aestivum L.) is one the most important cereal crop grown worldwide. The genetic improvement of any breeding population largely depends on the extent of genetic variability present in a crop species. In the present investigation, forty diverse bread wheat genotypes were evaluated for genetic variability, heritability, and genetic advance at the Research Farm of Kisan (PG) College, Simbhaoli, Hapur (U.P.) during rabi season 2021-22. The genotypes were grown in randomized block design with three replications and data were collected on eleven morphological characters. Analysis of variance showed highly significant differences among the genotypes for all the characters studied, indicating availability of wide range of variability among the genotypes. Higher values of PCV and GCV were recorded for grain yield/plant, harvest index, tillers/plant and biological yield/plant. Heritability estimates were highest for 1000 grains weight followed by days to heading, grain yield/plant and plant height. The estimates of genetic advance (GA) were highest for grain yield/plant, harvest index and biological yield/plant. High heritability along with high genetic advance (per cent of mean) was observed for grain yield/plant, harvest index and biological yield/plant which suggested that selection for these characters would be more effective for desired genetic improvement.
Emergency Department Use Across Income Groups Following an Increase in Cost-Sharing
Authors: Wu Yushan , Wang Dorothy Yingxuan , Zhao Shi , Wang Maggie Haitian , Wong Eliza Lai-yi , Yeoh Eng-kiong 
Published: August 2023

ImportanceTo encourage the appropriate utilization of emergency care, cost-sharing for emergency care was increased from HK$100 (US $12.8) to HK$180 (US $23.1) per visit in June 2017 in all public hospitals in Hong Kong. However, there are concerns that this increase could deter appropriate emergency department (ED) visits and be associated with income-related disparities.ObjectiveTo examine changes in ED visits after the fee increase.Design, Setting, and ParticipantsThis retrospective cohort study used administrative data from June 2015 to May 2019 from all public hospitals in Hong Kong. Participants included all Hong Kong residents aged 64 years and younger, categorized into low-income, middle-income, and high-income groups according to the median household income in their district of residence. Data analysis was performed from May to June 2023.Main Outcomes and MeasuresThe primary outcome was the ED visit rate per 100 000 people per month, categorized into 3 severity levels (emergency, urgent, and nonurgent). Secondary outcomes include general outpatient (GOP) visit rate, emergency admission rate, and in-hospital mortality rate per month at public hospitals. Segmented regression analyses were used to estimate changes in the level and slope of outcome variables before and after the fee increase.ResultsThis study included a total of 5 441 679 ED patients (2 606 332 male patients [47.9%]; 2 108 933 patients [38.5%] aged 45-64 years), with 2 930 662 patients (1 407 885 male patients [48.0%]; 1 111 804 patients [37.9%] aged 45-64 years) from the period before the fee increase. The fee increase was associated with an 8.0% (95% CI, 7.1%-9.0%) immediate reduction in ED visits after June 2017, including a 5.9% (95% CI, 3.3%-8.5%) reduction in urgent visits and an 8.9% (95% CI, 8.0%-9.8%) reduction in nonurgent visits. In addition, a 5.7% (95% CI, 4.7%-6.8%) reduction of emergency admissions was found, whereas no significant changes were observed in in-hospital mortality. Specifically, a statistically significant increase in GOP visits (4.1%; 95% CI, 0.9%-7.2%) was found within the low-income group, but this association became insignificant after controlling for the social security group, who were exempted from payment, as a control.Conclusions and RelevanceIn this cohort study, the fee increase was not associated with changes in ED visits for emergency conditions, but there was a negative and significant association with both urgent and nonurgent conditions across all income groups. Considering the marginal increase in public GOP services, further study is warranted to examine strategies to protect low-income people from avoiding necessary care.
GJA3 Genetic Variation and Autosomal Dominant Congenital Cataracts and Glaucoma Following Cataract Surgery
Authors: Boese Erin A. , Drack Arlene V. , Roos Benjamin R. , Alward Wallace L. M. , Tollefson Mallory R. , Schnieders Michael J. , Scheetz Todd E. , Boldt H. Culver , Stone Edwin M. , Fingert John H. 
Published: August 2023

ImportanceThe p.Asp67Tyr genetic variant in the GJA3 gene is responsible for congenital cataracts in a family with a high incidence of glaucoma following cataract surgery.ObjectiveTo describe the clinical features of a family with a strong association between congenital cataracts and glaucoma following cataract surgery secondary to a genetic variant in the GJA3 gene (NM_021954.4:c.199G&amp;gt;T, p.Asp67Tyr).Design, Setting, and ParticipantsThis was a retrospective, observational, case series, genetic association study from the University of Iowa spanning 61 years. Examined were the ophthalmic records from 1961 through 2022 of the family members of a 4-generation pedigree with autosomal dominant congenital cataracts.Main Outcomes and MeasuresFrequency of glaucoma following cataract surgery and postoperative complications among family members with congenital cataract due to the p.Asp67Tyr GJA3 genetic variant.ResultsMedical records were available from 11 of 12 family members (7 male [63.6%]) with congenital cataract with a mean (SD) follow-up of 30 (21.7) years (range, 0.2-61 years). Eight of 9 patients with congenital cataracts developed glaucoma, and 8 of 8 patients who had cataract surgery at age 2 years or younger developed glaucoma following cataract surgery. The only family member with congenital cataracts who did not develop glaucoma had delayed cataract surgery until 12 and 21 years of age. Five of 11 family members (45.5%) had retinal detachments after cataract extraction and vitrectomy. No patients developed retinal detachments after prophylactic 360-degree endolaser.Conclusions and RelevanceThe GJA3 genetic variant, p.Asp67Tyr, was identified in a 4-generation congenital cataract pedigree from Iowa. This report suggests that patients with congenital cataract due to some GJA3 genetic variants may be at especially high risk for glaucoma following cataract surgery. Retinal detachments after cataract extraction in the first 2 years of life were also common in this family, and prophylactic retinal endolaser may be indicated at the time of surgery.
Sphingosine‐1‐Phosphate Receptor Targeted PLGA Nanobubbles for Inflammatory Vascular Endothelial Cell Catching
Authors: Tang Jian , Liu Yang , Li Mingxi , Wang Xiao , Du Anning , Gu Ning , Yang Fang 
Published: August 2023

AbstractVascular inflammation is an early manifestation and common pathophysiological basis of numerous cardiovascular and cerebrovascular diseases. However, effective surveillance methods are lacking. In this study, sulfur hexafluoride (SF6)‐loaded polylactic acid‐co‐glycolic acid (PLGA) nanobubbles (NBs) with a surface assembly of cyclodextrin (CD) and sphingosine‐1‐phosphate (S1P) (S1P@CD‐PLGA NBs) are designed. The characterization results show that S1P@CD‐PLGA NBs with diameters of ≈200 nm have good stability, biosafety, and ultrasound imaging‐enhancement effects. When interacting with inflammatory vascular endothelial cells, S1P molecules encapsulated in cyclodextrin cavities exhibit a rapid, excellent, and stable targeting effect owing to their specific interaction with the highly expressed S1P receptor 1 (S1PR1) on the inflammatory vascular endothelial cells. Particularly, the S1P–S1PR1 interaction further activates the downstream signaling pathway of S1PR1 to reduce the expression of tumor necrosis factor‐α (TNF‐α) to protect endothelial cells. Furthermore, mouse models of carotid endothelial injuries and mesenteric thrombosis demonstrate that S1P@CD‐PLGA NBs have excellent capabilities for in vivo targeting imaging. In summary, this study proposes a new strategy of using S1P to target inflammatory vascular endothelial cells while reducing the expression of TNF‐α, which has the potential to be utilized in the targeted surveillance and treatment of vascular inflammatory diseases.
Enhanced Operational Stability by Cavity Control of Single‐Layer Organic Light‐Emitting Diodes Based on Thermally Activated Delayed Fluorescence
Authors: Li Yungui , Van der Zee Bas , Tan Xiao , Zhou Xin , Wetzelaer Gert‐Jan A. H. , Blom Paul W. M. 
Published: August 2023

AbstractHighly efficient organic light‐emitting diodes (OLEDs) based on thermally activated delayed fluorescence (TADF) emitters are realized in recent years, but the device lifetime needs further improvement for practical display or lighting applications. In this work, a device design principle is presented by tuning the optical cavity of single‐layer undoped devices, to realize efficient and long‐lived TADF OLEDs. Extending the cavity length to the second‐order interference maximum by increasing the emissive layer thickness broadens the recombination zone, while the optical outcoupling efficiency remains close to that of the thinner first‐order devices. Such a device design leads to efficient and stable single‐layer undoped OLEDs with a maximum external quantum efficiency of 16%, an LT90 of 452 h, and an LT50 of 3693 h at an initial luminance of 1000 cd m−2, which is doubled compared to the first‐order counterparts. It is further demonstrated that the widely‐used empirical relation between OLED lifetime and light intensity originates from triplet–polaron annihilation, resulting in an extrapolated LT50 at 100 cd m−2 of close to 90 000 h, approaching the demands for practical backlight applications.
p‐Phenylenediamine‐Bridged Binder‐Electrolyte‐Unified Supramolecules for Versatile Lithium Secondary Batteries
Authors: Nam Myeong Gyun , Moon Janghyeon , Kim Minjun , Koo Jin Kyo , Ho Jeong‐Won , Choi Gwan Hyun , Kim Hye Jin , Shin Chang‐Su , Kwon Seok Joon , Kim Young‐Jun , Chang Hyuk , Kim Youngugk , Yoo Pil J. 
Published: August 2023

AbstractThe binder is an essential component in determining the structural integrity and ionic conductivity of Li‐ion battery electrodes. However, conventional binders are not sufficiently conductive and durable to be used with solid‐state electrolytes. In this study, a novel system is proposed for a Li secondary battery that combines the electrolyte and binder into a unified structure, which is achieved by employing para‐phenylenediamine (pPD) moiety to create supramolecular bridges between the parent binders. Due to a partial crosslinking effect and charge‐transferring structure of pPD, the proposed strategy improves both the ionic conductivity and mechanical properties by a factor of 6.4 (achieving a conductivity of 3.73 × 10−4 S cm−1 for poly(ethylene oxide)‐pPD) and 4.4 (reaching a mechanical strength of 151.4 kPa for poly(acrylic acid)‐pPD) compared to those of conventional parent binders. As a result, when the supramolecules of pPD are used as a binder in a pouch cell with a lean electrolyte loading of 2 µL mAh−1, a capacity retention of 80.2% is achieved even after 300 cycles. Furthermore, when it is utilized as a solid‐state electrolyte, an average Coulombic efficiency of 99.7% and capacity retention of 98.7% are attained under operations at 50 °C without external pressure or a pre‐aging process.
Wheat and faba bean intercropping and cultivar impacts on morphology, disease, and yield
Authors: De Long Jonathan R. , van Malland Floor , de Buck Abco , van den Berg Merlijn 
Published: August 2023

AbstractModern agriculture relies heavily on synthetic fertilizer and pesticide inputs. Pressure is increasing to find alternatives that reduce such inputs. In comparison to monocultures, intercropping can reduce plant diseases and increase yield, thereby reducing inputs and maximizing land use efficiency. However, knowledge gaps remain regarding which crop and cultivar combinations maximize such benefits. Here, we grew two wheat (Triticum aestivum L.) and six faba bean (Vicia faba L.) cultivars in monoculture and intercrops over three seasons and measured plant morphology, disease prevalence, and yield. Wheat ear development was slower in monocultures but varied by cultivar and year. Wheat cultivars senesced faster in monocultures versus certain faba bean intercrop combinations. In both wheat cultivars, Fusarium spp. severity was higher, while yellow rust (Puccinia striiformis f.sp. tritici Westend.) was lower in monocultures versus intercropped plots but varied by year and faba bean cultivar. Chocolate spot (Botrytis fabae Sardiña) in faba bean was higher in the cultivar ‘Louhi’ when grown in monoculture. Wheat cultivars yielded higher in monoculture versus intercropped plots. Faba bean yield was higher in monocultures but depended on wheat cultivar and year. Land equivalent ratios (LER) were not affected by interactions between cultivars or years but were always above one in intercropped plots. This indicates that it is always more efficient for yield to intercrop. Our results show that the benefits of intercropping with different wheat and faba bean cultivars varied, indicating that specific goals (i.e., disease suppression and yield) should be considered when selecting wheat–faba bean cultivar combinations.