bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nonfused Ring Electron Acceptors for Ternary Polymer Solar Cells with Low Energy Loss and Efficiency Over 18%
Authors: Tan Hua , Fan Weixue , Zhu Mengbing , Zhu Jianing , Wang Xunchang , Xiao Manjun , Yang Renqiang , Zhu Weiguo , Yu Junting 
Published: August 2023

AbstractTernary polymer solar cells(PSCs) have been identified as an effective approach to improving power conversion efficiency (PCE) of binary PSCs. However, most of the third component, especially Y‐series non‐fullerene acceptors, is a fused ring acceptor which often requires a rather tedious synthesis and the use of hazardous organostannane reagents. In this work, two nonfused ring acceptors IOEH‐4F and IOEH‐N2F are synthesized by a green synthetic route and incorporated into PM6:Y6 blend. Encouragingly, the IOEH‐4F and IOEH‐N2F‐based ternary PSCs exhibited more efficient charge transfer, exciton separation, and lower energy loss than PM6:Y6‐based PSCs. And the IOEH‐4F and IOEH‐N2F‐based ternary PSCs achieved an impressive PCE of 17.80% and 18.13%, respectively, which are higher than that of PM6:Y6 based PSCs (16.18%). Notably, these PCE values are also the highest PCEs for ternary PSCs including non‐fused ring acceptors. Importantly, even when the IOEH‐N2F:Y6 ratios increased from 0.05:1.2 to 0.50:1.2, the PCE of IOEH‐N2F‐based ternary PSCs (16.70%) are still higher than that of PM6:Y6 based PSCs, indicating the great potential for cost saving. It is believed that the findings will help the design of better nonfused ring acceptors and the optimization of corresponding ternary PSCs with cost‐saving advantage.
Ultralow Ru Single Atoms Confined in Cerium Oxide Nanoglues for Highly‐Sensitive and Robust H2O2‐Related Biocatalytic Diagnosis
Authors: Yuan Minjia , Li Qian , Wu Zihe , Zhu Huang , Gao Yang , Zhou Mi , Luo Xianglin , Wang Mao , Cheng Chong 
Published: August 2023

AbstractExploring highly efficient, portable, and robust biocatalysts is a great challenge in colorimetric biosensors. To overcome the challenging states in creating single‐atom biocatalysts, such as insufficient activity and stability, here, this work has engineered a unique CeO2 support as nanoglue to tightly anchor the Ru single‐atom sites (CeO2‐Ru) with strong electronic coupling for achieving highly sensitive and robust H2O2‐related biocatalytic diagnosis. The morphology and chemical/electronic structure analysis demonstrates that the Ru atoms are well‐dispersed on CeO2 surface to form high‐density active sites. Benefiting from the unique structure, the prepared CeO2‐Ru exhibits outstanding peroxidase (POD) like catalytic activity and selectivity to H2O2. Steady‐state kinetic study results show that the CeO2‐Ru presents the highest Vmax and turnover number than the state‐of‐the‐art POD‐like biocatalysts. Consequently, the CeO2‐Ru discloses a high efficiency, good selectivity, and robust stability in the colorimetric detection of L‐cysteine, glucose, and uric acid. Notably, the limit of detection (LOD) can reach 0.176 × 10−3 m for the L‐cysteine, 0.095 × 10−3 m for the glucose, and 0.088 × 10−3 m for the uric acid via cascade reaction. This work suggests that the proposed unique CeO2 nanoglue will offer a new path to create single‐atom noble metal biocatalysts and take a step closer to future biotherapeutic and biocatalytic applications.
Revealing the Subzero‐Temperature Electrochemical Kinetics Behaviors in Ni‐Rich Cathode
Authors: Meng Fanbo , Zhang Haolin , Xiong Xingyu , Li Xiangjie , Wu Rufeng , Han Qiying , Qin Bo , Yuan Bin , Hu Renzong 
Published: August 2023

AbstractThe sluggish kinetics in Ni‐rich cathodes at subzero temperatures causes decreased specific capacity and poor rate capability, resulting in slow and unstable charge storage. So far, the driving force of this phenomenon remains a mystery. Herein, with the help of in‐situ X‐ray diffraction and time of flight secondary ion mass spectrometry techniques, the continuous accumulation of both the cathode electrolyte interphase (CEI) film formation and the incomplete structure evolution during cycling under subzero temperature are proposed. It is presented that excessively uniform and thick CEI film generated at subzero temperatures would block the diffusion of Li+‐ions, resulting in incomplete phase evolution and clear charge potential delay. The incomplete phase evolution throughout the Li+‐ion intercalation/de‐intercalation processes would further cause low depth of discharge and poor electrochemical reversibility with low initial Coulombic efficiency, as well. In addition, the formation of the thick and uniform CEI film would also consume Li+‐ions during the charging process. This discovery highlights the effects of the CEI film formation behavior and incomplete phase evolution in restricting electrochemical kinetics under subzero temperatures, which the authors believe would promote the further application of the Ni‐rich cathodes.
Organic Intercalation Induced Kinetic Enhancement of Vanadium Oxide Cathodes for Ultrahigh‐Loading Aqueous Zinc‐Ion Batteries
Authors: Song Zhihang , Zhao Yi , Zhou Anbin , Wang Huirong , Jin Xiaoyu , Huang Yongxin , Li Li , Wu Feng , Chen Renjie 
Published: August 2023

AbstractVanadium‐based oxides have attracted much attention because of their rich valences and adjustable structures. The high theoretical specific capacity contributed by the two‐electron‐transfer process (V5+/V3+) makes it an ideal cathode material for aqueous zinc‐ion batteries. However, slow diffusion kinetics and poor structural stability limit the application of vanadium‐based oxides. Herein, a strategy for intercalating organic matter between vanadium‐based oxide layers is proposed to attain high rate performance and long cycling life. The V3O7·H2O is synthesized in situ on the carbon cloth to form an open porous structure, which provides sufficient contact areas with electrolyte and facilitates zinc ion transport. On the molecular level, the added organic matter p‐aminophenol (pAP) not only plays a supporting role in the V3O7·H2O layer, but also shows a regulatory effect on the V5+/V4+ redox process due to the reducing functional group on pAP. The novel composite electrode with porous structure exhibits outstanding reversible specific capacity (386.7 mAh g−1, 0.1 A g−1) at a high load of 6.5 mg cm−2, and superior capacity retention of 80% at 3 A g−1 for 2100 cycles.
How do thinking styles and STEM attitudes have effects on computational thinking? A structural equation modeling analysis
Authors: Jiang Haozhe , Islam A. Y. M. Atiquil , Gu Xiaoqing , Guan Jia 
Published: August 2023

AbstractComputational thinking (CT) is vital for success in numerous domains. However, the nature, definition, and scope of CT are ill‐defined, and research on how best to develop CT is very limited. This study focused on how thinking styles and STEM attitudes have effects on computational thinking. Using a proportionate stratified random sampling procedure, 1195 students from two universities were surveyed. A structural equation modeling analysis showed that students' thinking styles and STEM attitudes directly predicted their computational thinking skills and that thinking styles mediated the relationship between STEM attitudes and computational thinking skills. Thinking styles and STEM attitudes are strong predictors of CT skills. Based on the results, we recommended that the conceptualization of CT be broadened to reflect its trans‐disciplinary nature within the context of STEM education. This study adds to the limited theoretical understanding of CT and CT‐predictors in higher education, which has been studied much less than in K‐12 education.
Exploring colorectal cancer survivors’ perspectives on improving care delivery and the role of e-health technology: a qualitative study
Authors: van Deursen Liza , Aardoom Jiska J. , Alblas Eva E. , Struijs Jeroen N. , Chavannes Niels H. , van der Vaart Rosalie 
Published: August 2023

Abstract
Purpose
The purpose of this study was to gather insights from colorectal cancer (CRC) survivors on how to improve care for CRC survivors and how e-health technology could be utilized to improve CRC care delivery.

Methods
Three semi-structured focus groups were held with sixteen CRC survivors. To initiate the discussion, an online registration form and two vignettes were used. The data was analyzed using the framework method.

Results
Based on survivors’ experiences, five themes were identified as opportunities for improving CRC care delivery. These themes include better recognition of complaints and faster referrals, more information as part of the care delivery, more guidance and monitoring of health outcomes, more collaboration between practitioners, and more attention for partners and relatives. In addition, survivors expressed opportunities for using e-health to facilitate information provision, improve communication, and monitor survivors’ health conditions.

Conclusion
Several suggestions for improvement of CRC care delivery were identified. These often translated into possibilities for e-health to support or improve CRC care delivery. The ideas of survivors align with the vast array of existing e-health resources that can be utilized to enhance CRC care delivery. Therefore, the next step involves addressing the implementation gap between the needs of stakeholders, such as CRC survivors and healthcare providers, and the e-health tools currently available in clinical practice.
Targeted delivery of a short antimicrobial peptide (CM11) against Helicobacter pylori gastric infection using concanavalin A-coated chitosan nanoparticles
Authors: Moosazadeh Moghaddam Mehrdad , Bolouri Shahin , Golmohammadi Reza , Fasihi-Ramandi Mahdi , Heiat Mohammad , Mirnejad Reza 
Published: August 2023

AbstractHelicobacter pylori is the cause of most cases of stomach ulcers and also causes some digestive cancers. The emergence and spread of antibiotic-resistant strains of H. pylori is one of the most important challenges in the treatment of its infections. The present study aims to develop a concanavalin A (ConA) coated chitosan (CS) nanocarrier-based drug delivery for the targeted release of peptides to the site of H. pylori infection. Accordingly, chitosan was used as an encapsulating agent for CM11 peptide delivery by applying ionotropic gelation method. Con-A was used for coating CS nanoparticles to target H. pylori. The CS NPs and ConA-CS NPs were characterized by FTIR, dynamic light scattering (DLS), and scanning electron microscopy (SEM). The MIC of CM11-loaded ConA-CS NPs against H. pylori SS1 strain was analyzed in vitro. In order to evaluate the treatment efficiency in vivo, a gastric infection model of H. pylori SS1 strain was established in mice and histopathological studies and IL-1β cytokine assay were performed. Based on the results, the size frequency for CS NPs and ConA-CS NPs was about 200 and 350 nm, respectively. The prepared CM11-loaded ConA-CS NPs exhibited antibacterial activity against H. pylori SS1 strain with a concentration of 32 µg/ml. The highest healing process was observed in synthesized CM11-loaded ConA-CS NPs treatments and a significant decrease in IL-1β was observed. Our findings highlight the potential of chitosan nanoparticles as a drug delivery vehicle in the treatment of gastric infection model of H. pylori SS1 strain.
Graphical Abstract
On the Path to Optimal Alchemistry
Authors: Lundborg Magnus , Lidmar Jack , Hess Berk 
Published: August 2023

AbstractAlchemical free energy calculations have become a standard and widely used tool, in particular for calculating and comparing binding affinities of drugs. Although methods to compute such free energies have improved significantly over the last decades, the choice of path between the end states of interest is usually still the same as two decades ago. We will show that there is a fundamentally arbitrary, implicit choice of parametrization of this path. To address this, the notion of the length of a path or a metric is required. A metric recently introduced in the context of the accelerated weight histogram method also proves to be very useful here. We demonstrate that this metric can not only improve the efficiency of sampling along a given path, but that it can also be used to improve the actual choice of path. For a set of relevant use cases, the combination of these improvements can increase the efficiency of alchemical free energy calculations by up to a factor 16.
Thermoelastic Stress Analysis in the Presence of Biaxial Stresses in Titanium: Effect of the Mean Stress on Errors in Stress Evaluation
Authors: Palumbo D. , De Finis R. 
Published: August 2023

Abstract
Background
Thermoelastic Stress Analysis (TSA) is a contactless technique capable of estimating superficial stresses on components subjected to dynamic loads. Surface stresses can be obtained by means of calibration methods that require the assessment of the thermoelastic constants. However, these methods can lead to errors in stress evaluation in those materials where the effect of the mean stress on the thermoelastic signal cannot be neglected (e.g., titanium).

Objective
The aim is the development of an analytic formulation of error made in first stress invariant amplitude evaluation for a biaxial stress state, when neglecting mean stress effect.

Methods
By considering the general theory of thermoelastic stress analysis accounting for the mean stress effect, the formulation of the thermoelastic effect in the presence of a biaxial stress state was obtained. The results were compared to those obtained by a numerical simulation and the proposed formulation has been validated for titanium by means of experimental tests.

Results
Firstly, the new formulation of thermoelastic temperature variations accounting for mean stress effect in presence of a biaxial stress state was provided. Secondly, an error analysis provided an analytical formulation for the error made in case mean stress effect is neglected for different case studies.

Conclusions
The error in stress evaluation can be considered as the error originating from the use of an incorrect calibration formula (traditional one)”. The new analytical formulation accounting for the general theory of thermoelastic stress analysis allows to account for the mean stress on titanium in the presence of a uniaxial and biaxial stress states and to evaluate the error made in neglecting such a second order effect when using TSA.
Genetic aspects underlying the normocalcemic and hypercalcemic phenotypes of primary hyperparathyroidism
Authors: Viviani Arianna , Colangelo Luciano , Ciminelli Bianca Maria , Novelletto Andrea , Sonato Chiara , Occhiuto Marco , Cipriani Cristiana , Diacinti Daniele , De Martino Viviana , Gianni Walter , Pepe Jessica , Minisola Salvatore , Malaspina Patrizia 
Published: August 2023

Abstract
Purpose
Hypercalcemic primary hyperparathyroidism (PHPT) is a common endocrine disorder that has been very well characterized. In contrast, many aspects of normocalcemic primary hyperparathyroidism (NPHPT) such as natural history, organ damage, and management are still matter of debate. In addition, both the pathophysiology and molecular basis of NPHPT are unclear. We investigated whether PHPT and NPHPT patient cohorts share the same pattern of genetic variation in genes known to be involved in calcium and/or bone metabolism.

Research design and methods
Genotyping for 9 single nucleotide polymorphisms (SNPs) was performed by Real-Time PCR (TaqMan assays) on 27 NPHPT and 31 PHPT patients evaluated in a tertiary referral Center. The data of both groups were compared with 54 in house-controls and 503 subjects from the 1000 Genomes Project. All groups were compared for allele/haplotype frequencies, on a single locus, two loci and multi-locus basis.

Results
The NPHPT group differed significantly at SNPs in OPG and ESR1. Also, the NPHPT cohort was peculiar for pairwise associations of genotypes and for the overrepresentation of unusual multilocus genotypes.

Conclusions
Our NPHPT patient set harbored a definitely larger quota of genetic diversity than the other samples. Specific genotypes may help in defining subgroups of NPHPT patients which deserve ad hoc clinical and follow-up studies.
RETRACTED ARTICLE: E-commerce User Recommendation Algorithm Based on Social Relationship Characteristics and Improved K-Means Algorithm
Authors: Shen Xia 
Published: August 2023

AbstractIn the era of the Internet, information data continue to accumulate, and the explosive growth of network information explosion leads to the reduction of the accuracy of users’ access to information. To enhance the user experience and purchasing desire of e-commerce users, a e-commerce user recommendation algorithm based on social relationship characteristics and improved K-means algorithm is proposed. It combines the Automatic Time Division Dynamic Topic Model based on adaptive time slice division for building a strength calculation model in view of the characteristics of social relations. Then, it proposes an e-commerce user recommendation algorithm in view of the improved K-means algorithm to improve the accuracy of topic feature extraction and user recommendation. The experiment illustrates that there is no fluctuation in the clustering function of the improved K-means algorithm, and the highest, lowest, and average accuracy remain consistent under the three datasets, with average accuracy of 78.9%, 84.5%, and 95.9%, respectively. The community discovery-based friend recommendation algorithm presented in the study has the highest accuracy, illustrating that improving the K-means algorithm can further improve recommendation accuracy. The accuracy of the feature extraction method in view of alternative cost is 0.63, which improves the accuracy by about 9%. The results indicate that this study can provide technical support for user recommendations on e-commerce platforms.
Rapid determination of domoic acid in seafood by fluorescence polarization immunoassay using a portable analyzer
Authors: Ogura Yu , Fukuyama Mao , Kasuya Motohiro , Shigemura Koji , Eremin Sergei A. , Tokeshi Manabu , Hibara Akihide 
Published: August 2023

AbstractMonitoring phycotoxin accumulation in marine products such as edible shellfish is a regulatory requirement in many countries. Therefore, a simple and rapid onsite quantification method is sought. Herein, we present a fluorescence polarization immunoassay (FPIA), a well-known one-step immunoassay, using a portable fluorescence polarization analyzer for domoic acid (DA), widely referred to as the primary toxin of amnesic shellfish poisoning (ASP). To establish FPIA for DA, the matrix effect of methanol, which is widely used to extract DA from shellfish, on FPIA was investigated. To validate this method, we performed a spike recovery test using oysters containing DA at a concentration equivalent to the regulatory limits of North America and the European Union (20 mg/kg). The recovery rate was found to be 79.4–114.7%, which is equivalent to that of the commercially available enzyme-linked immunosorbent assay (ELISA). We expect that this FPIA system will enable the quantitative onsite analysis of DA and significantly contribute to the safety of marine products.
Graphical Abstract
Tropical Storms and Hurricanes in New Orleans Lead to Increased Rates of Violent Injury
Authors: Ghio Michael , Ghio Caroline , Campbell Alexandra , Fleckman Julia , Theall Katherine , Constans Joseph , Tatum Danielle , McGrew Patrick , Duchesne Juan , Taghavi Sharven 
Published: August 2023

Abstract

Objective:
The effects of named weather storms on the rates of penetrating trauma is poorly understood with only case reports of single events currently guiding public health policy. This study examines whether tropical storms and hurricanes contribute to trauma services and volume.

Methods:
This was a cross-sectional review of tropical storms/hurricanes affecting New Orleans, Louisiana, during hurricane seasons (June 1–November 30) from 2010–2021, and their association with the rate of penetrating trauma. Authors sought to determine how penetrating trauma rates changed during hurricane seasons and associate them with demographic variables.

Results:
There were 5531 penetrating injuries, with 412 (7.4%) occurring during landfall and 554 (10.0%) in the aftermath. Black/African Americans were the most affected. There was an increase in the rate of penetrating events during landfall (3.4 events/day) and aftermath (3.5 events/day) compared to the baseline (2.8 events/day) (P = < 0.001). Using multivariate analysis, wind speed was positively related to firearm injury, whereas the rainfall total was inversely related to firearm violence rates during landfall and aftermath periods. Self-harm was positively related to distance from the trauma center.

Conclusions:
Cities at risk for named weather storms may face increasing gun violence in the landfall and aftermath periods. Black/African Americans are most affected, worsening existing disparities. Self-harm may also increase following these weather events.
REASSESSING THE CHRONOLOGY OF TOPARÁ EMERGENCE AND PARACAS DECLINE ON THE PERUVIAN SOUTH COAST: A BAYESIAN APPROACH
Authors: Osborn Jo , Hundman Brittany , Weinberg Camille , Espino Huaman Richard 
Published: August 2023

ABSTRACTThrough Bayesian analysis of new radiocarbon dates, this paper demonstrates that the Topará tradition did not emerge until after Paracas monumental sites were ritually closed in the Chincha Valley of the Peruvian south coast. These findings controvert a long-held hypothesis of Topará as a foreign tradition which intruded into the Paracas heartland and initiated the period of transformation known as the Paracas-Nasca transition. We present the first radiocarbon dates from Jahuay, the earliest accepted Topará site. These dates are compared with new analyses of published radiocarbon dates from three other sites associated with this transitional period: a Late Paracas politico-ceremonial site in the Chincha Valley, a Late Paracas settlement in the Palpa Valley in the Río Grande de Nasca Drainage, and an Initial Nasca site in the same valley. This work shows Paracas site closures began earlier than has previously been appreciated and demonstrates that the first appearance of the Topará ceramic style post-dates the onset of Paracas decline in the region’s northern valleys. This analysis represents a successful attempt to develop a radiocarbon-based chronology across a calibration plateau by incorporating stratigraphic data into a Bayesian model.
We Do Not Know the Population of Every Country in the World for the Past Two Thousand Years
Authors: Guinnane Timothy W. 
Published: August 2023

Economists have reported results based on populations for every country in the world for the past two thousand years. The source, McEvedy and Jones’ Atlas of World Population History, includes many estimates that are little more than guesses and that do not reflect research since 1978. McEvedy and Jones often infer population sizes from their view of a particular economy, making their estimates poor proxies for economic growth. Their rounding means their measurement error is not “classical.” Some economists augment that error by disaggregating regions in unfounded ways. Econometric results that rest on McEvedy and Jones are unreliable.“… we haven’t just pulled the figures out of the sky. Well, not often.”—McEvedy and Jones (1978, p. 11)