bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of cadmium stress on fruits germination and growth of two herbage species
Authors: Hu Ying , Wang Huichun , Zhou Biyao , Li Zhengke , Jia Huiping , Deji Pengmao , Liu Nian , Wei Jingjing 
Published: April 2023

Abstract
Cadmium (Cd) pollution is a global environmental problem. It is of great significance to find a kind of pasture that can grow normally in a cadmium environment, especially in the Tibetan Plateau. We studied the fruit germination and fruit growth of Elymus sinsubmuticus S.L. Chen and Elymus tangutorum (Nevski), native plants of the Tibetan Plateau, in different cadmium environments. The results showed that with increased cadmium stress, the fruit germination rate, final germination rate, fruit-vigor, average germination time, and germination-speed index for the two grass species gradually decreased, and the 50% germination time for the seed gradually increased. Root length, biomass, and the number of leaves decreased in both species. We quantified the fruit germination and growth of plants in the cadmium environment and found that E. sinosubmuticus S.L. Chen had better fruit germination and fruit growth, and it had the development potential of cadmium pollution control.
Tectorigenin alleviates the apoptosis and inflammation in spinal cord injury cell model through inhibiting insulin-like growth factor-binding protein 6
Authors: Zhou Liqiang , Yan Kui , Xing Shuxing , Cheng Jun 
Published: April 2023

AbstractSince tectorigenin has been reported to possess anti-inflammation, redox balance restoration, and anti-apoptosis properties, we determine to unravel whether tectorigenin has potential in alleviating spinal cord injury (SCI). Herein, PC12 cells were induced by lipopolysaccharide (LPS) to establishin vitroSCI models. The cell viability and apoptosis were detected through cell counting kit-8 and flow cytometry assays. The caspase-3/8/9 content was measured by colorimetric method. Western blot was conducted to quantify the expressions of cleaved caspse-3/8/9, IGFBP6, TLR4, IκBα, p-IκBα, RELA proto-oncogene, p65, and p-p65. Enzyme-linked immunosorbent assay and real-time quantitative polymerase chain reaction were carried out to quantitate expressions of IGFBP6, interleukin-1β (IL-1β), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α). SwissTargetPrediction and GSE21497 database were utilized to predict the potential therapeutic targets of tectorigenin. Comparison of IGFBP6 expression in SCI tissues and normal tissues was analyzed by GEO2R. Our study found that LPS induced the declined cell viability, elevated cell apoptosis, upregulation of caspase-3/8/9, cleaved caspase-3/8/9, IL-1β, IL-6, TNF-α, IGFBP6, and TLR4, and the activation of IκBα and p65 in PC12 cells. Tectorigenin reversed the above effects of LPS. IGFBP6 was predicted to be the potential therapeutic target of tectorigenin and was overexpressed in SCI tissues. Notably, IGFBP6 overexpression offset the effects of tectorigenin on PC12 cells. In conclusion, tectorigenin could alleviate the LPS-induced apoptosis, inflammation, and activation of NF-κB signaling in SCI cell models via inhibiting IGFBP6.
Microstructure and electrical contact behavior of the nano-yttria-modified Cu-Al2O3/30Mo/3SiC composite
Authors: Zhu Hanjing , Tian Baohong , Zhang Yi , Zhou Meng , Li Yunzhang , Zheng Xianhua , Liang Shengli , Liu Shuang , Sun Wenyu , Liu Yong , Volinsky Alex A. 
Published: April 2023

Abstract
With the rapid development of the copper-based composite in the field of electrical contact material industry, the problem of poor arc erosion resistance of the copper-based material becomes more and more prominent. Improving the arc erosion resistance of the copper-based composite is an urgent problem to be solved. Cu-Al2O3/30Mo/3SiC and 0.5Y2O3/Cu-Al2O3/30Mo/3SiC electrical contact composites were prepared in a fast-hot-pressing sintering furnace. The microstructure and phase structure of the composites were analyzed by using a scanning electron microscope, transmission electron microscope, and X-ray diffraction meter, respectively. The arc erosion properties of the composites at 25 V, DC and 10-30 A were investigated by using a JF04C electric contact tester. The mass loss of the composites was reduced by 77.8%, and the arc erosion rate was reduced by 79.6% after the addition of nano-yttrium oxide under the experimental conditions of 25 V, DC and 30 A. At the same time, the arc energy and welding force of the composite after switching operations decreased, indicating that the addition of nano-yttria improved the arc erosion resistance of the composite. This work provides a new method for improving the arc erosion resistance of the copper-based composite contact material.
Molecular and phenotypic markers for pyramiding multiple traits in rice
Authors: Carsono Nono , Tambunan Reisyi R. , Sari Santika , Wicaksana Noladhi 
Published: April 2023

Abstract
Gene pyramiding has been developed for effective resistant genes, such as bacterial blight resistance genes. However, in this report, pyramiding for multiple traits is presented. We evaluated 28 pyramided rice lines derived from 7 hybridizations of valuable parents for high yield potential, early maturity, aroma, high grain quality, and resistance to brown planthopper using both simple-sequence repeat markers and phenotypic markers. Pyramided rice genotypes were evaluated with RM282 molecular marker linked to GW3 gene associated with grain weight, RM259 (number of panicles), RM3600 (length of panicles), RM3701 (short panicles), RM19414 (Hd3), RM7601 (Hd2), RM190, and SSIIa (waxy), IFAP and ESP (aroma), RM586 (Bph3 and Bph4), and RM8213 (Qpbh4 and Bph17(t)). Eight genotypes (i.e., #9, #15, #16, #22, #25, #26, #27, and #28) were confirmed to have desired genes associated with multiple important traits based on molecular markers and morpho-agronomic traits. A strong correlation was found between RM19414 and heading date, between specific markers for aroma and sensory test. Meanwhile, a weak correlation was found between RM259 with panicle number, RM586, and RM8213 with trichome density. As presented in this study, gene pyramiding promises a new hope to combine multiple traits in rice breeding. Promising rice lines will be incorporated in the multiple traits breeding program.
Non‐apoptotic caspase activation ensures the homeostasis of ovarian somatic stem cells
Authors: Galasso Alessia , Xu Derek Cui , Hill Claire , Iakovleva Daria , Stefana Maria Irina , Baena‐Lopez Luis Alberto 
Published: April 2023

AbstractCurrent evidence has associated caspase activation with the regulation of basic cellular functions without causing apoptosis. Malfunction of non‐apoptotic caspase activities may contribute to specific neurological disorders, metabolic diseases, autoimmune conditions and cancers. However, our understanding of non‐apoptotic caspase functions remains limited. Here, we show that non‐apoptotic caspase activation prevents the intracellular accumulation of the Patched receptor in autophagosomes and the subsequent Patched‐dependent induction of autophagy in Drosophila follicular stem cells. These events ultimately sustain Hedgehog signalling and the physiological properties of ovarian somatic stem cells and their progeny under moderate thermal stress. Importantly, our key findings are partially conserved in ovarian somatic cells of human origin. These observations attribute to caspases a pro‐survival role under certain cellular conditions.
Pemanfaatan Limbah Daun sebagai Lightweight Expanded Carbon Aggregate (LECA) untuk Media Tanam Hidroponik
Authors: Rosita Nita , Wati Annisa Lidia , Fauzi Adi Ahmad , Prayogi Devin Sidiq , Aji Mahardika Prasetya 
Published: April 2023

Lightweight Expanded Carbon Aggregate (LECA) adalah media yang lazim digunakan sebagai media tanam hidroponik. Densitas LECA yang kecil menyebabkan massa LECA menjadi sangat ringan. Porositas dari media ini dipengaruhi oleh pori. Pori berperan meningkatkan kemampuan menyimpan air dari LECA. Pada umumnya, LECA dibuat dari bahan baku tanah liat yang diperlakukan pada tekanan dan suhu yang tinggi sehingga dihasilkan media yang ringan dengan porositas yang tinggi. Limbah daun dapat dimanfaatkan karena memiliki kandungan karbon yang tinggi. Penelitian ini bertujuan menemukan pembuatan LECA berbahan baku limbah daun. Pembuatan LECA dilakukan dengan mencampurkan karbon yang berasal dari pembakaran limbah daun dengan PEG sebagai agen pembentuk pori dan PVAc sebagai perekat. LECA yang dihasilkan dikarakterisasi dengan menghitung nilai porositasnya dan mengujikan LECA sebagai media tanam hidroponik. Hasil perhitungan menunjukkan bahwa peningkatan persentase PEG akan meningkatkan porositas LECA. Sedangkan hasil uji LECA sebagai media tanam dibuktikan dengan tanaman Lili Paris dan biji kangkung yang tumbuh dengan baik setelah ditumbuhkan diatas media LECA.
Identifikasi Panasbumi Krakal dengan Menggunakan Metode Geomagnetik sebagai Informasi Pengembangan dan Pembangunan Lanjutan Daerah Berpotensi
Authors: Chaerunnisah Lela Fahmi , Santoso Ivan Hadi , Sukmaya Fajar , Saputro Eko , Winahyu Diah Ika , Khumaedi Khumaedi 
Published: April 2023

Potensi panas bumi Krakal terletak di Kabupaten Kebumen, Jawa Tengah. Fenomena panas bumi di daerah ini ditunjukkan dengan adanya mata air hangat yang terletak di Desa Krakal, Kecamatan Alian, Kabupaten Kebumen. Untuk memanfaatkan potensi panas bumi suatu area dibutuhkan suatu proses penelitian yang bertujuan mengidentifikasi sistem panas buminya. Metode geomagnetik merupakan salah satu metode geofisika yang sering digunakan untuk survei pendahuluan pada eksplorasi panas bumi. Pengukuran geomagnetik dilakukan dengan menggunakan alat Proton Precession Magnetometer (PPM), Global Positioning Sistem (GPS), kompas geologi, log book dan meteran. Dari pengukuran di lapangan diperoleh data intensitas medan magnet total. Pengukuran intensitas medan magnet total di sekitar Pemandian Air Panas (PAP) Krakal dilakukan di titik-titik pengukuran sebagai titik-titik sampel pengambilan data geomagnetik. Titik-titik sampel pengambilan data geomagnetik dianggap mewakili seluruh populasi yaitu batuan bawah permukaan di daerah penelitian. Analisis utama terhadap data penelitian adalah anomali magnetik di sekitar Pemandian Air Panas (PAP) Krakal. Selanjutnya data anomali diinterpretasikan dengan pemodelan untuk mendapatkan struktur batuan di bawah permukaan bumi. Hasil pengolahan dan interpretasi data menunjukkan daerah penelitian termasuk dalam kelompok anomali magnetik sedang berkisar antara -120 nT sampai 80 nT. Nilai negatif dari anomali magnetik mencerminkan efek dimineralisasi batuan sebagai akibat adanya zona temperatur tinggi, daerah ini ditafsirkan sebagai daerah prospek panas bumi.
Tahu Nikah (Nigari Kacang Merah) Sebagai Bentuk Diversifikasi Makanan Sehat Ramah Lingkungan
Authors: Ilahiyyah Inayatun , Mulyati Sri , Ningsih Indri Septi , Nindhita Lokika Nityama , Sari Resta Rahma 
Published: April 2023

Tahu Aci merupakan salah satu makanan khas daerah Tegal. Proses produksi tahu pada umumnya menggunakan koagulan (senyawa penggumpal) berupa Kalsium sulfat (CaSO4) yang dikenal sebagai batu tahu atau sioko, asam cuka, dan biang tahu atau cairan bekas perasan tahu yang diinapkan (Koswara, 2009:7). Koagulan tersebut dapat menghasilkan limbah cair yang mencemari lingkungan. Bahan baku pembuatan tahu adalah kedelai yang ternyata 70% masih impor (Pusat Data dan Sistem Informasi Pertanian Outlook Komoditas Kedelai, 2015). Berdasarkan hal tersebut, maka dilakukan inovasi, dengan tujuan untuk mendiversifikasi tahu, mendiversifikasi Tahu NIKAH, serta mengetahui prospek penjualan Tahu NIKAH di lingkungan masyarakat daerah Tegal dan masyarakat umum. Tahu NIKAH (nigari kacang merah) merupakan bentuk diversifikasi tahu dengan bahan dasar kacang merah dan koagulan nigari. Diversifikasi Tahu NIKAH berupa Dimsum Nigari Kacang Merah (DINIKAHI) yang berbahan dasar Tahu NIKAH, kulit pangsit basah, dan dengan irisan wortel. Brownies Kacang Merah (BROKARAH) dengan bahan utama kulit ari kacang merah. Puding Nigari Kacang Merah (PURIKARAH) dengan komposisi air rebusan sari kacang merah dan tepung agar-agar. Produksi Tahu NIKAH sudah berjalan 13 kali produksi dengan keseluruhan omzet sebesar Rp3.681.000,00. Pengembangan dan keberlanjutan program ini dengan mendirikan cafe Tahu NIKAH melalui serangkaian tahapan. PKM-K ini menghasilkan bentuk diversifikasi makanan yang sehat dan ramah lingkungan dengan tingkat penjualan yang tinggi.
Menerapkan Pembelajaran TGT Media TTS Pada Bank Soal Berbasis LKS Sistem Koloid
Authors: Dewi Brigitta Elga Kusuma 
Published: April 2023

Metode pembelajaran Teams Games Tournament (TGT) adalah salah satu tipe pembelajaran kooperatif yang menempatkan siswa dalam kelompok-kelompok belajar yang beranggotakan 5 sampai 6 orang siswa yang memiliki kemampuan, jenis kelamin, suku kata atau ras yang berbeda. Metode pembelajaran TGT sebagai suatu upaya untuk membantu siswa dalam memahami soal dengan media teka teki silang. Media teka teki silang diharapkan dapat meningkatkan kreatifitas dan motivasi siswa. Media teka teki silang akan lebih menarik perhatian siswa dan membuat siswa merasa lebih tertantang untuk menyelesaikan soal. Media teka teki silang diharapkan mambu mengembangkan aspek kognitif dan afektif pada siswa. Dalam pelaksanaanya media TGT terdiri dari 5 tahapan yaitu class precentation, teams, games, tournament, dan team recognition. Pada 5 tahapan yang ada didalam media pembelajaran TGTÂ bertujuan untuk membantu siswa dalam mengerjakan bank soal sistem koloid berbasis web dengan media teka teki silang. Penerapan bank soal berbasis LKS dapat digunakan untuk mengetahui karakteristik butir soal yang baik berdasarkan tingkat kesulitan.
Pengaruh Sekolah Inklusi terhadap Kepekaan Sosial Anak SD Slerok 2 Kota Tegal
Authors: Wijayanti Tarindra Puspa , Afita Wiwi , Wilantanti Grehas 
Published: April 2023

Kepekaan sosial adalah kemampuan seseorang untuk bereaksi secara cepat dan tepat terhadap objek atau situasi sosial tertentu yang ada di sekitarnya. Lingkungan sekitar anak akan sangat mempengaruhi kepekaan sosial anak. Sekolah inklusi adalah salah satu sarana untuk meningkatkan kepekaan sosial anak karena di dalamnya terdapat anak berkebutuhan khusus yang dapat melatih kepedulian terhadap sesama. Penelitian yang telah dilakukan bertujuan untuk menganalisis dan mendeskripsikan pengaruh sekolah inklusi terhadap kepekaan sosial anak SD Slerok 2 Kota Tegal. Metode penelitian yang digunakan dalam penelitian ini adalah metode deskriptif kuantitatif. Populasi dan sampel penelitian adalah siswa ATBK (anak tanpa berkebutuhan khusus) kelas III,IV,V, dan VI SD Slerok 2 Kota Tegal yang berjumlah 117 siswa. Teknik pengambilan sampel yang digunakan adalah teknik jenis sampling jenuh. Teknik pengumpulan data dilakukan dengan: 1); Angket 2) Wawancara; dan 3) Dokumentasi. Metode analisis data terdiri dari: analisis deskriptif, uji prasyarat, dan analisis regresi linear sederhana. Hasil penelitian menunjukan bahwa sekolah inklusi berpengaruh positif dan signifikan terhadap kepekaan sosial anak sebesar 37,5%, sedangkan sisanya 73,5% dipengaruhi oleh faktor lain yang tidak diteliti dalam penelitian ini. Hasil penelitian diperoleh thitung ttabel (8,087 1,982) dan korelasi keduanya sebesar 0,612, yaitu dalam kategori kuat. Â Social sensitivity is the ability of a person to react quickly and precisely to certain objects or social situations around him. The environment around children will greatly affect the social sensitivity of children. Inclusion schools are one of the means to improve children's social sensitivity because in them there are children with special needs who can train caring for others. This research aims to analyze and describe the influence of inclusive schools on childrenâ€™s social sensitivity in SD Slerok 2 Kota Tegal. The research method used in this research is quantitative descriptive method. The population and sample of this study are normal students (nondisable)class III, IV,V, and VI to SD Slerok 2 Kota Tegal amounting to 117 students. The sampling technique used is saturated sampling technique. Data collection techniques used are: 1 ) Questionare; 2) interviews; and 3)Documentation. Data analysis method used descriptive analysis, prerequisite analysis, and final analysis. The results of the study indicate that inclusive schools have a positive and significant effect on children`s social sensitivity by 37,5 %. The result of the study obtained tcount ttable (8,087 1,982) and the correlation between them wa 0,612, which is in the strong category.
Comparative analysis of START and CAVI arterial stiffness scores in hypertensive patients
Authors: Sumin A. N. , Shcheglova A. V. , Bakholdin I. B. 
Published: April 2023

Aim. To compare the novel arterial stiffness index START and the cardio-ankle vascular index (CAVI) in hypertensive (HTN) patients. Material and methods. A total of 709 people with HTN aged 24 to 64 years were examined by volume sphygmography using VaSera VS-1000 (Fukuda Denshi, Japan). CAVI and START values obtained retrospectively from pulse wave velocity and blood pressure were studied using an online calculator.Results. The median CAVI score was within the normal range (<9,0): 7,5 (6,6; 8,4) on the right and 7,4 (6,5; 8,4) on the left. The median of the START index was 6,25 (5,0; 7,55) on the right and 6,4 (5,1; 7,8) on the left. For young people (21-30 years old), the median START score was 4,47, for the CAVI index — 6,25 (p>0,05). In the older age group (61-70 years), the median START index was 7,27, for the CAVI index — 8,4 (p>0,05). The growth pattern of the START score with age was higher by 38,5% than the CAVI index by 25,6% (p=0,034). A high degree of correlation between CAVI and START was noted (r=0,823, p<0,001). Parameters were associated with age (r=0,412 for CAVI and r=0,355 for START; p<0,001), smoking duration (r=0,390 and r=0,361; p<0,001), glomerular filtration rate (r=-0,317 and r= -0,318; p<0,001), body mass index (r=-0,176 and r=-0,185; p=0,001). For the CAVI index, a relationship was found with the glucose level (r=0,192; p<0,001) and a sedentary lifestyle (r=-0,157; p=0,04), while for the START index — with the creatinine level (r=0,143; p=0,01).Conclusion. Patients with hypertension showed a high correlation between the novel START index and the CAVI score (r=0,823, p<0,001). The indicators had similar associations with risk factors, which is important for the subsequent practical application of the START index.
Phytochemical Analysis and Antioxidant Potential of Ethylacetate Extract of Tamarindus Indica (Tamarind) Leaves by Frap Assay
Authors: Dahiru Mubarak Muhammad , Ahmadi Hadiza , Faruk Maimuna Umar , Hamman Huzaifa Huzaifa Aminu , Charles Abreme Gahana 
Published: April 2023

Oxidative stress is characterized by an imbalance in the generation of free radicals and their subsequent elimination by endogenous antioxidants. It is a characteristic of several diseases, especially during the progression stage, which can lead to fatal effects. This study aims to investigate the phytochemical components and antioxidant capability of Tamarindus indica and assess its capability as a candidate for managing diseases associated with oxidative stress. The gravimetric method detected and quantified phytochemicals, while the reducing power assay determined the antioxidant potential. Saponins, steroids, and flavonoids were detected in 6.83 ±0.44, 4.30 ±0.60, and 10.17% ±0.60, respectively, without alkaloids, glycosides, and terpenoids. The antioxidant test showed a concentration-dependent increase in absorbance of both the extract and standard (Ascorbic acid). However, Ascorbic acid had higher absorbance. At 100% concentration, the sample had an absorbance of 0.388 ±0.022, which was lower than the absorbance of Ascorbic acid (0.411 ±0.009) at 40% concentration. It can be concluded that Tamarind leaves could be utilized to manage diseases associated with oxidative stress, evidenced by their antioxidant potential credited to the phytochemical content of the leaves. However, there is a need for further studies to ascertain the exact compounds and their modes of action.
TAFSIR DAN PEMBAHARUAN PEMIKIRAN ISLAM DI INDONESIA ERA KEMERDEKAAN
Authors: Setiawan Ahmad Bayu 
Published: April 2023

The conflict dynamics of revivalist and traditionalist Islamic groups always colorize development of ideological contest of religious live in Indonesia. One of the important episodes of this conflict dynamic occurred in the era of independence. Through this paper, the author is interested in portraying episodes of Islamic Revivalist dynamics in the independence era through the thoughts and works of influential revivalist scholars, namely Ahmad Hassan. This study aims to reveal the form of mediation of Ahmad Hassan's Islamic renewal in his book of tafsir Al-Furqan. The author uses a descriptive method of analysis with literature study techniques in reviewing the interpretation of Al-Furqan as the main object of research. The results showed that in mediating Ahmad Hassan's Islamic renewal, Kitab tafsir Al-Furqan accommodates and mediates Islamic renewal in two ways, namely formative and substantive ways. Formative way of mediation is indicated through the form of tafsir Al-Furqan as a literal and meaningful translation of tafsir. Critically, this form of translation aimed to make Al-Furqan accessible for Indonesian people at that time when they haven’t had proper understanding on Arabic literacy so that people could understand and refer to the meaning of the Qur'an directly. This is in line with Ahmad Hassan's renewal though about the Qur'an and hadith as the main sources of muslims. As for the substantive ways of mediation, tafsir Al-Furqan contains and expresses the thoughts of Ahmad Hassan's renewal as a substance in interpreting the verses of the Qur'an.
Sustainable Food Agricultural Land Preservation at Sleman Regency, Indonesia: An Attempt to Preserve Food Security
Authors: Widhiyastuti Alfia Nisa , Adjie Erra Melanie Ariesta , Fauzan Adhia Azhar , Supriyadi Supriyadi 
Published: April 2023

<span lang="EN-US">Urban</span><span lang="EN-US"> development and increasing population impact improving the demand for non-agricultural land. Through the issuance of Law No. 41 of 2009 concerning the Protection of Sustainable Food Agricultural Land, the government has attempted to reduce the conversion rate of agricultural land by protecting paddy fields that are considered the potential for food supply. This study aims to examine the impact of the transformation of agricultural land to non-agricultural land on food security and the implementation of the of Law No. 41 of 2009. The research method used is survey and descriptive. The focus of discussion includes population growth, land change, land area, harvested area, production and food availability needs data. The data was gathered from field observations, interviews and a literature study. The results showed that the average decrease in paddy fields in the last three years was 98.87 ha. The population density in Sleman Regency is classified as high. In 2018 to 2019 the population density increased by 22.88 people km<sup>-2</sup>. In 2019 to 2020 the population density decreased by 163.35 people km<sup>-2</sup>. In 2018 to 2019 rice productivity increased by 625 tons ha<sup>-1</sup>, although harvested area and production have declined. There is no </span><span lang="IN">correlation </span><span lang="EN-US">between the location of paddy fields, population and rice productivity. The food security condition in Sleman Regency is generally stable, but the site of paddy fields that continues to decrease yearly must still be a concern.</span>