bluuebunny/crossref_metadata_2025_split huggingface dataset:
Magnetic resonance imaging of the ankle: Pathology of the anterior and medial compartments
Authors: Smith Paul Edmund , McManus Luke Joseph , Morey Matthew , Kong Andrew 
Published: February 2023

SummaryMagnetic resonance imaging (MRI) is the gold standard for imaging the tendons and the ligaments of the ankle. MRI combines excellent tissue contrast and accurate anatomic delineation of joint structures. In this pictorial essay, the first of two parts, we delineate the ankle into anatomic compartments and use this as a template for describing pathology in each compartment.
Stability and safety of transbronchial dye mixture for preoperative localization in a porcine model
Authors: Yoo Wan Ho , Kim Sae Rom , Kim Soo Han , Lee Jongggeun , Mok Jeongha , Shin Dong Hoon , Ahn Hyo Yeong , Eom Jung Seop 
Published: February 2023

AbstractObjectiveFor thoracoscopy, the usefulness of a dye mixture of indigo carmine and Lipiodol for localizing lung lesions has been reported. However, little is known about the stability and safety of this dye mixture injected on the visceral pleura through a bronchoscope.MethodsPorcine models were divided into three groups according to the detection time of the dye mixture: group A with a detection time of 4 h; group B, 8 h; and group C, 24 h. A dye mixture of indigo carmine and Lipiodol (0.5 mL each) was sprayed onto the visceral pleura both in the ventral and dorsal regions via a spray catheter.ResultsTwelve markings were created on the visceral pleura of the porcine lung (six ventral and six dorsal) in the six porcine models. At predetermined detection times, all 12 dye markings (100%) were visible on the visceral pleura. The mean longest diameter of the dye marking in the ventral and dorsal regions was 18.8 mm and 24.3 mm, respectively. In groups B and C, pathological changes in the lymphatic system, such as lymphatic dilatations, were found; minimal changes were found in group B, however, these changes with oval‐shaped lymphatic cysts and Lipiodol accumulation, were more evident in group C.ConclusionsThe dye mixture of indigo carmine and Lipiodol had reliable stability and visibility. In terms of safety, it may be necessary to check the dye mixture on the lung surface within 8 h.
Digital diagnostic cytopathology: Has the pandemic brought us closer?
Authors: Girolami Ilaria , Eccher Albino 
Published: February 2023

AbstractThe COVID‐19 pandemic has acted as a powerful change driver in the field of pathology and has had relevant consequences on the practice of cytopathology, in terms of changes in workload, rates of malignancy, and the performance of cytology. At the same time, regulatory authorities have relaxed their requirements for the deployment of digital pathology for remote diagnostic reporting. However, most of these improvements have concerned digital histopathology. Data from a literature search show that experiences in digital cytopathology during the pandemic have concerned mainly educational and academic activities. From a broader point of view, when searching for all published literature on digital pathology, only a minority of papers deal with cytopathology, but a noticeable increase in publications has been seen in the last 10 years, with an upward trend toward a maximum of papers in 2021. Indeed, the pandemic has led to greater awareness of the possibility of digital for cytopathology as well.
A novel community‐based therapeutic education program for reducing alcohol‐related harms and stigma in people with alcohol use disorders: A quasi‐experimental study (ETHER study)
Authors: Barré Tangui , Ramier Clémence , Antwerpes Saskia , Costa Marie , Bureau Morgane , Maradan Gwenaelle , Di Beo Vincent , Cutarella Christophe , Leloutre Jacques , Riccobono‐Soulier Olivier , Hedoire Sophie , Frot Elodie , Vernier Fabienne , Vassas‐Goyard Stéphanie , Dufort Sabine , Protopopescu Camelia , Marcellin Fabienne , Casanova Danielle , Coste Marion , Carrieri Patrizia 
Published: February 2023

AbstractIntroductionAlcohol use disorder (AUD) is associated with a significant disease burden in France, where alcohol use is deeply rooted in culture. However, the treatment gap is large because of several barriers, including stigmatisation and drinkers' apprehension about total abstinence. However, standardised and evidence‐based interventions based on controlled‐drinking for people with AUD are lacking. We aimed to assess the effectiveness of a novel community‐based French therapeutic patient education (TPE) program for people with AUD named Choizitaconso.MethodsA before‐after non‐randomised quasi‐experimental study, named ETHER, was designed and implemented with people living with AUD, over a period of 6 months. The primary outcome was percentage change in the number of alcohol‐related harms experienced. Secondary outcomes were percentage changes in psycho‐social patient‐reported and community‐validated outcomes. Participants in the intervention group (n = 34) benefited from the 10‐week TPE program Choizitaconso, while the comparison group (n = 58) received standard care. The Kruskall–Wallis and chi‐squared or Fisher's exact tests were used to compare before‐after changes in variables in both groups. Linear regression models were used to test for the effect of study group on each outcome and to test for the effect of alcohol consumption as a confounder.ResultsAt 6 months, all outcomes but one either remained stable or numerically improved in both groups. Internalised stigma significantly improved in the intervention group (p = 0.026) but not in the comparison group (p = 0.207), with a significant group effect (p = 0.014).Discussion and ConclusionsThis study demonstrates the effectiveness of the Choizitaconso TPE program on community‐validated outcomes, especially internalised stigma.
3D‐gedruckte Moulagen für die individualisierte HDR‐Brachytherapie kutaner Malignome im Gesichtsbereich: Erste klinische Erfahrungen
Authors: Chatzikonstantinou Georgios , Diefenhardt Markus , Fleischmann Maximilian , Meissner Markus , Scherf Christian , Trommel Martin , Ramm Ulla , Rödel Claus , Tselis Nikolaos , Licher Jörg 
Published: February 2023

ZusammenfassungHintergrund und ZielsetzungDie Strahlentherapie älterer sowie gebrechlicher Patienten mit kutanen Malignomen im Gesichtsbereich kann eine klinische Herausforderung darstellen. Dies ist der erste Bericht über die klinischen Erfahrungen mit individualisierten 3D‐gedruckten Moulagen zur High‐Dose‐Rate (HDR)‐Brachytherapie (BT) kutaner Malignome im Gesichtsbereich.Patienten und MethodikFünfzehn Patienten, welche nicht einer radikalen Operation oder definitiven externen Strahlentherapie (EBRT) zugänglich waren, wurden unter Verwendung 3D‐gedruckter Moulagen mittels HDR‐BT behandelt. Patientenauswahl und Indikationsstellung erfolgten im Rahmen einer multidisziplinären dermatologischen Tumorkonferenz. Es werden die ersten onkologischen Ergebnisse unter Berücksichtigung der Toxizität und Kosmesis berichtet.ErgebnisseDas mediane Patientenalter betrug 77 Jahre. Histologisch lag bei sieben Patienten ein Plattenepithelkarzinom, bei fünf ein Basalzellkarzinom, bei jeweils einem ein Melanoma in situ, eine Lentigo maligna und ein Melanom vor. Die verordnete Strahlendosis betrug median 39 Gy appliziert in einmaltäglich verabreichten Fraktionsdosen zu 3 Gy. Bei einer medianen Nachbeobachtungszeit von 12,2 Monaten trat bei einem Patienten mit Melanoma in situ ein Lokalrezidiv auf. Mit Ausnahme eines radiogenen Katarakts Grad 4 wurde keine weitere Spättoxizität > Grad 2 dokumentiert.SchlussfolgerungenDie HDR‐BT mittels 3D‐gedruckte Moulagen ist eine sichere und gut verträgliche Technik für die strahlentherapeutische Behandlung von insbesondere älteren und gebrechlichen Patienten mit fazialen kutanen Malignomen. Sie kann in Fällen von funktioneller Inoperabilität oder kritischer Tumorlage für eine definitive EBRT als effektive lokale Therapiemodalität in Frage kommen.
Nachhaltigkeit in der dermatologischen Praxis und Klinik: Herausforderungen und Lösungsansätze
Authors: Niebel Dennis , Herrmann Alina , Balzer Susanne , Hecker Christina , Koch Susanne , Luhmann Esther , Becker‐Weimann Su Youn , Tischler Max , Löffler Christin , Saha Susanne 
Published: February 2023

ZusammenfassungFortbestehender hoher Ressourcenverbrauch bedingt die Überschreitung der planetaren Belastungsgrenzen; moderne Gesundheitssysteme tragen zu dieser Problematik bei. Um dies zu adressieren, bietet dieser Artikel eine Übersicht zu ausgewählten Aspekten nachhaltiger Maßnahmen in Praxis und Klinik, die auch für die Dermatologie von Relevanz sind. Konkrete Handlungsfelder liegen im Bereich energetischer und baulicher Maßnahmen, Verkehr und Mobilität, Praxisorganisation inklusive Digitalisierung sowie Personal und Evaluation. Weiterhin werden in diesem Artikel spezielle Aspekte der Hygiene und Reinigung, Dermatochirurgie und Verordnungsverhalten beleuchtet. Externa und Kosmetika werden hierbei gesondert diskutiert, da diese in der Dermatologie eine Sonderstellung einnehmen. Darüber hinaus werden Informationen zu bereits etablierten nachhaltigen Initiativen im Gesundheitswesen zusammengestellt. Ziel des Artikels ist es, zur Reflexion gängiger ärztlicher Praxis und zur Implementation nachhaltiger Maßnahmen anzuregen.
Sulphonylureas versus metformin and the risk of ventricular arrhythmias among people with type 2 diabetes: A population‐based cohort study
Authors: Islam Nehal , Reynier Pauline , Douros Antonios , Yu Oriana H. Y. , Filion Kristian B. 
Published: February 2023

AbstractAimTo determine whether the use of sulphonylurea monotherapy, compared with metformin monotherapy, is associated with an increased risk of ventricular arrhythmia (VA) among patients initiating pharmacotherapy for type 2 diabetes.Research Design and MethodsWe conducted a population‐based cohort study using electronic health data extracted from the UK's Clinical Practice Research Datalink Aurum. Using the active comparator, new‐user cohort design, we compared rates of VA among patients aged 18 years or older using sulphonylurea monotherapy with those using metformin monotherapy as their initial pharmacological treatment for type 2 diabetes from April 1998 to December 2019. We used a Cox proportional hazards model with inverse probability of treatment weighting by propensity score to estimate the adjusted hazard ratio (aHR) and a corresponding bootstrap 95% confidence interval (CI) for VA with sulphonylurea monotherapy versus metformin monotherapy.ResultsThe cohort included 92 638 new users of sulphonylurea and 506 882 new users of metformin. A total of 279 VA events occurred among sulphonylurea users (rate per 10 000 person‐years: 25.5, 95% CI: 22.7 to 28.7) and 1537 VA events occurred among metformin users (rate per 10 000 person‐years: 18.5, 95% CI: 17.6 to 19.5). Compared with metformin, sulphonylureas were associated with an increased risk of VA (aHR: 1.42, 95% CI: 1.18 to 1.69).ConclusionsSulphonylureas are associated with an increased risk of VA when used as first‐line therapy for type 2 diabetes relative to metformin use. This increased risk should be considered when prescribing sulphonylureas as an initial treatment for type 2 diabetes.
Why is the West unique in linking religiosity to market friendliness?
Authors: Czeglédi Pál 
Published: February 2023

AbstractThe Integrated Values Survey shows that the positive relationship between religiosity and market friendliness is a uniquely Western feature. With the help of public choice theory, the author hypothesises that this Western uniqueness is the result of the way the dimensions of political ideologies are formed in the West. The hypothesis is supported by regressing an index of market friendliness on a religiosity index, political identity, and a measure of ‘ideological capital’. Accounting for the latter two, the positive association of religiosity with market friendliness vanishes, even in the West.
Business schools and faculty experiences of sexism: Gender structure tensions within and outside these schools
Authors: Hughes Emma , Donnelly Rory 
Published: February 2023

AbstractIn this paper, we advance knowledge and theorization on the sexism experienced by faculty not only inside but also outside the physical boundaries of business schools. We enrich existing knowledge of gender and sexism by applying Gender Structure Theory (GST) to provide a more multi‐dimensional analysis of the role of individuals, interactions, and institutions in shaping gender structures. Engaging with this theoretical framework, we use mixed‐methods and data, integrating statistical data on gender in UK business schools with qualitative data from interviews with 52 academics from 15 schools to provide a nuanced insight into sexism at business schools. The framework developed from the findings extends GST by adding a specific “organizational” dimension, which is needed to examine interorganizational differences and how cultural and material organizational processes are influenced by wider national/international processes. We also identify three key interactional tensions cutting across the dimensions examined: organizational versus interorganizational relations, agency versus dependency, and employment relationships versus stakeholder relationships. The findings generate pressing implications for policy and practice in business schools and academia more broadly.
Physical activity in Norwegian teenagers and young adults with haemophilia A compared to general population peers
Authors: Matlary Ruth Elise D. , Grydeland May , Glosli Heidi , Rueegg Corina Silvia , Holme Pål André 
Published: February 2023

AbstractIntroductionLimited evidence exists on objectively measured habitual physical activity (PA) of young people with haemophilia (PWH).AimsTo compare different outcomes of objective PA between young PWH A and controls using a commercial activity tracker.MethodsWe enrolled males aged 13–30 years with moderate and severe haemophilia A, without inhibitors on regular prophylaxis. PA was measured with the activity tracker Fitbit Charge 3 for 12 weeks. Control group data was obtained from ≈60,000 Fitbit users, matched on age, sex and measurement period. PA variables [steps, intensities, volume, activity types, exercise frequencies and proportion meeting the World Health Organization's moderate‐to‐vigorous PA (MVPA) recommendations] were compared between groups descriptively and using Welch's two‐sample t‐test and two‐sample test of proportions.ResultsForty PWH A were enrolled (mean age 19.5 years, 50% teenagers, 50% adults, three (7.5%) with moderate and 37 (92.5%) with severe haemophilia). Mean daily steps and minutes MVPA were similar between PWH and controls. PWH spent more time in light PA (mean 227 vs. 192 min/day, P = .033) and exercised more frequently (mean 5.6 vs. 3.9 exercise sessions/week, P < .001). Among teenagers, 40% PWH and 8% controls reached MVPA recommendations, compared to 95% and 100% among adults. The most common type of PA was walking.ConclusionThis cohort of young PWH A on prophylactic treatment had PA levels comparable to controls. Still, a considerable proportion of teenagers did not meet the recommended weekly volume of MVPA, and we encourage clinicians to have a particular focus on promoting PA for this group.
Rodent odour bait: A new bumble bee conservation tool to enhance nest box occupancy
Authors: Varner Elana , Mark Kayla , Jackson Hanna , Singleton Kendal , Luo Laura , Johnson Sarah , Gries Regine , Gries Gerhard 
Published: February 2023

Abstract
Bumble bee conservation focuses on supplementing floral resources. Yet, nesting site availability is linked to bumble bee abundance. As a supplement to natural nest sites, nest boxes could be deployed and baited with synthetic lures.
As queen bumble bees reportedly establish colonies in abandoned rodent burrows, we hypothesized (1) that queen bumble bees sense, and behaviourally respond to, rodent odour, and (2) that lures of synthetic rodent odour can guide spring queens to nest boxes.
We collected headspace odorants from bedding soiled with urine and faeces of house mice, Mus musculus, and identified the 10 odorants that elicited responses from queen antennae.
To field‐test attraction of queens to mouse excreta odorants, we tree‐mounted paired nest boxes in florally rich locations, and assigned clean and soiled bedding, respectively, to one box in each pair.
Queens established colonies in 17 mouse‐scented boxes and in six unscented boxes. This 43% occupancy rate of mouse‐scented boxes represents a significant improvement over the 10% occupancy rate common for unscented boxes. In a further field experiment, we baited one box in each pair with a synthetic mouse odour lure and found that queens established colonies in 13 baited boxes and in six unbaited control boxes. Specifically, Bombus mixtus established seven colonies in baited boxes and only one colony in an unbaited box.
With this proof‐of‐concept that synthetic lures can guide queens to nest boxes, we anticipate that bumble bee conservation programs will soon be able to offer both expanded floral resources and baited nest boxes readily detectable by queens.
Water deficit as a trigger to immature soybean pod opening
Authors: Moura Lorena de Oliveira , da Silva Martha Freire , da Cunha Fernando França , Picoli Edgard Augusto de Toledo , Silva Francisco Charles dos Santos , da Silva Felipe Lopes 
Published: February 2023

AbstractRecently, the opening of immature and green pods has been identified in some soybean genotypes and it has raised concern. The cause of this opening has not been elucidated yet, but there is some evidence it may be associated with water‐deficit occurrences. Thus, this study aimed to verify the influence of water deficit on the opening of immature pods and correlate this feature with other agronomic traits. For this purpose, two trials using 99 soybean genotypes were carried out in a greenhouse. The plants were kept under two irrigation treatments: control treatment (soil kept at water potential of −33 kPa) and water‐deficit treatment (soil kept at water potential of −900 kPa, imposed between the R3 and R6 development stages). The number of immature open pods was analysed descriptively and we found that, in both trials, the water‐deficit treatment favoured the opening of immature pods of some genotypes. In trial 1, we evidenced that, under water deficit, grains tend to have greater volumes, and thus, the pod does not bear the size of the grain and shatters. In trial 2, in addition to water deficit, other factors acted on grain size and, consequently, on the opening of immature pods. According to the correlation analysis, the other evaluated agronomic traits did not behave in a consistent way in the two trials, and so they would not be recommended for the indirect selection of the opening of immature pods. Besides water deficit, other soil and climate factors might affect this process of immature pod opening.
An Exploration of an Improved Aggregate Student Growth Measure Using Data from Two States
Authors: Castellano Katherine E. , McCaffrey Daniel F. , Lockwood J. R. 
Published: February 2023

AbstractThe simple average of student growth scores is often used in accountability systems, but it can be problematic for decision making. When computed using a small/moderate number of students, it can be sensitive to the sample, resulting in inaccurate representations of growth of the students, low year‐to‐year stability, and inequities for low‐incidence groups. An alternative designed to address these issues is to use an Empirical Best Linear Prediction (EBLP), which is a weighted average of growth score data from other years and/or subjects. We apply both approaches to two statewide datasets to answer empirical questions about their performance. The EBLP outperforms the simple average in accuracy and cross‐year stability with the exception that accuracy was not necessarily improved for very large districts in one of the states. In such exceptions, we show a beneficial alternative may be to use a hybrid approach in which very large districts receive the simple average and all others receive the EBLP. We find that adding more growth score data to the computation of the EBLP can improve accuracy, but not necessarily for larger schools/districts. We review key decision points in aggregate growth reporting and in specifying an EBLP weighted average in practice.
A questionnaire study on disparity of cervical cancer prevention programs in Asia‐Oceania
Authors:   The Oncology Committee, Asia and Oceania Federation of Obstetrics and Gynecology, Tse Ka Yu , Ushijima Kimio , Tan Ai Ling , Intasorn Perapong , Pariyar Jitendra , Chang Chih‐Long , Domingo Efren J. , Konar Hiralal , Kumarasamy Suresh , Tjokroprawiro Brahmana Askandar , Wilailak Sarikapan 
Published: February 2023

AbstractBackgroundDespite the introduction of cervical cancer screening and human papillomavirus (HPV) vaccines, the utilization pattern was not standardized. The aim of this study was to elicit the current prevention care in Asia‐Oceania.MethodsAn online questionnaire was circulated to different countries/cities in Asia‐Oceania. The primary objective was to evaluate the coverage of HPV vaccination and cervical screening programs. The secondary objectives were to study the structures of these programs. Five case scenarios were set to understand how the respondents manage the abnormal screening results.ResultsFourteen respondents from 10 countries/cities had participated. Cervical cancer ranked the first in Myanmar and Nepal. About 10%–15% did not have national vaccination or screening program. The estimated coverage rate for vaccination and screening varied from less than 1% to 70%, which the coverage ran in parallel with the incidence and mortality rates of cervical cancer. All regions approved HPV vaccines, although only four provided free or subsidized programs for nonavalent vaccine. Cervical cytology remained the most common screening tool, and 20%–30% relied heavily on visual inspection using acetic acid. The screening age groups varied in different regions. From the case scenarios, it was noted that some respondents tended to offer more frequent screening tests or colposcopy than recommended by international guidelines.ConclusionThis study revealed discrepancy in the practice of cervical cancer prevention in Asia‐Oceania especially access to HPV vaccines. There is an urgent need for a global collaboration to eliminate cervical cancer by public education, reforming services, and medical training.