bluuebunny/crossref_metadata_2025_split huggingface dataset:
La voz pasiva en español y el sesgo teórico presente en el material didáctico E/LE
Authors: Gutiérrez Böhmer Sofía , Morón Usandivaras Mariana 
Published: January 2025

Este trabajo indaga sobre la relación entre manuales de enseñanza de Español como Lengua Extranjera, gramáticas pedagógicas y estudios teóricos dedicados al estudio de la voz pasiva en español. En particular, se analiza el sesgo teórico presente en los manuales, sesgo que a menudo centra su interés en aspectos morfosintácticos de las construcciones lingüísticas, descuidando las diferencias semántico-pragmáticas que influyen en la selección de las formas. Para ello, se atiende a la comparación que estos trabajos establecen entre la pasiva perifrástica, por un lado, y, por el otro, la voz activa, la pasiva refleja, la construcción de estar + participio, las construcciones impersonales y las de objeto directo antepuesto, destacando similitudes pragmáticas y semánticas. Se propone una enseñanza que fomente la comprensión de estas relaciones, siguiendo sugerencias de Gutiérrez Böhmer y Morón Usandivaras (2022).
Trunk muscle behaviors during the full-cycle stoop and squat lifting tasks
Authors: Pan Fumin , Wang Wei , Kong Chao , Lu Shibao 
Published: January 2025

Background
Lifting is generally considered as a risk factor for low back pain. A thorough investigation of the muscle function during lifting is essential for a better assessment of the potential risk of muscle impairment and towards improvements in lifting strategy. We aimed to compare the activities of the trunk muscles between the stoop and the squat lifting tasks.

Methods
A surface electromyography device was used to measure the muscle activity during the full-cycle squat and the stoop lifting tasks of a 5-kg weight. Each task was divided into four stages: stage 1 was bending forward to reach the weight, stage 2 was lifting the weight up, stage 3 was lowering the weight down, and stage 4 was returning to the upright position. The maximum electromyographic (EMG) activities among different tasks and different stages were compared. Eighteen males aged 20–35 years without low back pain were included, with a mean age of 26.55 ± 2.12 years, body height of 175.18 ± 4.29 cm, body weight of 69.27 ± 4.29 kg, and BMI of 22.56 ± 0.87 kg/m2.

Results
During stoop lifting, the median values of the absolute EMG of the left multifidus were 53.96, 70.32, 51.08 and 64.14 uV from stage 1 to stage 4, which were all non-significantly lower than those during squat lifting for 79.84, 103.64, 71.72 and 95.72, respectively (P > 0.05). The absolute EMG was greatest during stage 2, then during stage 4, stages 1 and 3 came next (Effect size = 0.879, P < 0.001). The median values of the normalized EMG of each muscle during stoop lifting were also non-significantly lower than those during squat lifting at each stage (P > 0.05). The normalized EMG was also greatest during stage 2, then during stage 4, and was lowest during stages 1 and 3 (Effect size = 0.932, P < 0.001).

Conclusion
The trunk muscles were similarly activated during squat and stoop lifting. During lowering the weight down, the trunk muscles were less activated than during extension to the upright position without weight in hands. These results could help to develop subject-specific strategies for lifting tasks to prevent or alleviate occupational low back pain.
Assessment of Antisickling and Antioxidant Properties of Mucuna pruriens and Gossypium hirsutum Leaves
Authors: Otoe Anthonia Iyekoretin , Nwogoh Benedict , Ogbeifun David E , Iyekowa Osaro , Okieimen Felix E 
Published: January 2025

Aim: In this study, the antioxidant and antisickling properties of Mucuna pruriens and Gossypium hirsutum leaves were determined.
Study Design: Experimental studies.
Place and Duration of Study: A patient with confirmed sickle cell disesase blood was got from the hematology unit of University of Benin Teaching Hospital, Benin City. Edo State. The procedure was carried out for 2 months.
Methods: Fresh Gossypium hirsutum and Mucuna pruriens leaves were obtained, identified, and then finely ground after being dried at room temperature. To obtain the extracts, five hundred grams (500g) of both leaves were macerated in one thousand milliliters (1000ml) of methanol solvent. The Ferric Reducing Antioxidant Power (FRAP) assay was used to determine the antioxidant activity of the extract.
In-vitro method of sickle cell hemoglobin polymerization assay was used in determining the antisickling properties of the plant extracts. A Patient with confirmed sickle cell disease (HbSS), at the University of Benin Teaching Hospital, Nigeria participated in this study by providing blood samples. The samples were collected when the patient was in a non-crisis state and was stored in sodium EDTA bottles. The samples were thoroughly mixed, and used immediately for analysis.
Results: The methanolic extracts of Gossypium hirsutum and Mucuna pruriens showed antioxidant property which varied somewhat at 85.9 ±0.05% for Mucuna pruriens and 87.4 ±0.04% for Gossypium hirsutum and tendered to be higher for Gossypium hirsutum leaf extract than for Mucuna pruriens leaf extract. The antioxidant property of the plant extract compared favorably with value up to 88 ±0.02% of that of reference, ascorbic acid. The plant extract showed antisickling effect that was both concentration of the plant extract and duration of application dependent when compared with the negative control, 17% sickling in the untreated HbSS sample, and 1% sickling with the reference p-hydroxybenzoic acid treated samples, the values marked antisickling effect.
Conclusion: The results of this research reveal that the methanolic extract of M. pruriens and G. hirsutum leaves have high antisickling and antioxidant properties.
Effect of Germination, Drying, Milling and Sieving on the Nutritional Quality of Foxtail Millet (Setaria italica)
Authors: Santhosh Aiswarya Velekat , T S Asif Ali , B Rajunaik , B Ramachandra 
Published: January 2025

Aims: The study aimed to evaluate the effect of germination, drying, milling and sieving on the protein and phytate content of foxtail millet
Study Design: This was an experimental, laboratory-based study.
Place and Duration of Study: The study was conducted at the Department of Dairy Microbiology, Dairy Science College, Hebbal, Bengaluru, Karnataka, India, between January 2024 and October 2024.
Methodology: Soaked foxtail millet (Setaria italica) was germinated at different time-temperature combinations (20, 25 and 30°C for 24, 48 and 72 hours). Germination was optimized based on its effects on reducing phytate content and enhancing protein content. Post-germination, the millet was dried at 20°C, 25°C, and 30°C to a final moisture content of 5–7%, ensuring uniform moisture reduction while preserving nutritional quality. The optimum drying temperature was selected based on its influence on protein and phytate levels. The dried millet was milled into fine flour and sieved through a 150-micron sieve to achieve uniform particle size. The protein content was determined using the micro-Kjeldahl method, while phytate content was estimated via titration with ferric chloride. Statistical analysis was performed using ANOVA, with a critical difference (CD) at a 5% significance level used to determine significance among treatments.
Results: Germination at 30°C for 48 hours resulted in the highest protein content (14.76%) and significantly reduced phytate levels (1.59 mol/kg). Drying at 30°C for 48 hours achieved a moisture content of 6.32%, with protein content increasing to 15.10% and phytate content slightly rising to 1.65 mol/kg. Milling and sieving further reduced both protein (13.23%) and phytate content (1.40 mol/kg), with a statistically significant reduction observed only in phytate levels.
Conclusion: Germination at 30°C for 48 hours significantly enhanced protein content and reduced phytate levels in foxtail millet, while drying and sieving processes further optimized nutritional quality. These findings highlight the potential of tailored processing techniques to improve the functional and nutritional value of millet-based products.
Pharmacokinetics of Enrofloxacin in Rohu (Labeo rohita): A Comparison of Bath, Intramuscular, and Oral Administration
Authors: Sreechandan Abhishek , Kalaiselvi L. , Hemamalini Nallaiah , Suresh E. , Shanmugam S. A. , Sriram P. 
Published: January 2025

Enrofloxacin, fluoroquinolone antibacterial drug is widely used in aquaculture for the control of infectious diseases. Understanding the pharmacokinetics of enrofloxacin in Labeo rohita is critical for developing optimized therapeutic strategies so as to maximize efficacy and to minimize the emergence of resistant pathogens. Hence, the present study was aimed at studying the pharmacokinetics of enroflocacin in rohu fish (Labeo rohita). The pharmacokinetics of enrofloxacin was studied after single intramuscular or oral administration at 10 mg/kg body weight and following bath exposure at the concentration of 5 mg/L for 5 h. Blood samples were collected at predetermined time intervals. The plasma concentrations of enrofloxacin were determined by high performance liquid chromatography. The pharmacokinetic parameters were analyzed using a non-compartmental method. Cmax and Tmax varied depending on the route of administration, with intramuscular administration resulting in highest plasma concentration in short Tmax indicating rapid and better absorption. Similarly, AUC0-∞ was found to be highest (166.51 μg.h.mL-1) following intramuscular administration indicating higher total systemic drug exposure compared to oral and bath exposure. Elimination half-life (t1/2) was found to be 43.31, 34.65, and 21.66 h following intramuscular, oral, and bath exposure, respectively. Intramuscular administration provided the highest plasma concentrations and the longest elimination half-life, suggesting its suitability for sustained treatment efficacy. The volume of distribution (Vd/F) was found to be maximum after oral administration (6.52 L/kg) as compared to the intramuscular route (3.75 L/kg) and bath exposure (2.07 L/kg). The results of our study indicate that enrofloxacin was well absorbed, widely distributed, and slowly eliminated in rohu following all three routes of administration. Our results suggest that enrofloxacin administered intramuscularly (10 mg/kg), orally (10 mg/kg), or by bath immersion (5 mg/L for 5 h) achieves sufficient plasma concentrations to treat pathogens with MIC ≤ 0.3 μg/mL.
Marketing and Supply Chain Analysis of Mushroom Production in Udham Singh Nagar District of Uttarakhand, India
Authors: Biswas Parth , Dev Chandra , Chavan Sanket D , Ali Sk Asraful , Prajapati Sunil Kumar 
Published: January 2025

The present study was designed with the prominent objective to evaluate marketing cost, margin, and efficiency. Samples of 60 mushroom growers were surveyed from two blocks of Udham Singh Nagar district. Based on the production, respondents were grouped into three categories viz. medium, small and marginal. For the analysis, Acharya’s method of marketing efficiency and Garrett’s ranking was used. From the study it was revealed that, marketing cost of per kg of mushroom in channel I, II and III was found Rs. 2.25, Rs. 23.66 and Rs. 40.1, respectively. Due to the absence of intermediaries, channel I had the highest modified marketing efficiency (MME). The study stressed the need for establishment of marketing facilities as a pre-requisite to promote mushroom production and also ensure remunerative price. Addressing marketing issue like problem in delay payment, storage and transportation are the major problems which will help to embrace this venture on a long run by creating more revenue.
Motivos mais Recorrentes que Causam o Indeferimento de Pedidos de Patente das Universidades Brasileiras
Authors: Ferreira Frederico Aldecoa , Filgueiras Rogério de Andrade 
Published: January 2025

Para obter patente no Brasil, é necessário que o pedido seja submetido ao exame técnico do Instituto Nacional da Propriedade Industrial (INPI) que avalia se o pedido cumpre com os requisitos legais dispostos na Lei de Propriedade Industrial (LPI). Nesse sentido, o objetivo deste artigo foi analisar indeferimentos publicados entre 2020 e 2022 para pedidos de patente de universidades, investigando os motivos pelos quais tais pedidos foram indeferidos. O procedimento metodológico empregou pesquisa documental por meio da análise das Revistas da Propriedade Industrial (RPIs) publicadas pelo INPI entre 2020 e 2022, identificando 927 indeferimentos publicados para pedidos de patente de universidades nesse período. Verificou-se que a ausência de atividade inventiva é a causa mais frequente de indeferimento, seguida de falta de clareza e/ou fundamentação das reivindicações e ausência de novidade.
Treatment Disparities in Radiation and Hormone Therapy Among Women Covered by Medicaid vs Private Insurance in Cancer Registry and Claims Data
Authors: Bradley Cathy J. , Sabik Lindsay M. , Liang Rifei , Lindrooth Richard C. , Perraillon Marcelo C. 
Published: May 2023

ImportancePrior research has reported undertreatment among patients with cancer who are insured by Medicaid, but this finding may be due, in part, to incomplete data in cancer registries.ObjectiveTo compare disparities in radiation and hormone therapy between women with breast cancer covered by Medicaid and those with private insurance using the Colorado Central Cancer Registry (CCCR) and CCCR data supplemented with All Payer Claims Data (APCD).Design, Setting, and ParticipantsThis observational cohort study included women aged 21 to 63 years who received breast cancer surgery. We linked the CCCR and Colorado APCD to identify Medicaid and privately insured women who were newly diagnosed with invasive, nonmetastatic breast cancer between January 1, 2012, and December 31, 2017. In the radiation treatment analysis, we narrowed the sample to women who received breast-conserving surgery (Medicaid, n = 1408; private, n = 1984) and in the hormone therapy analysis, we selected women who were hormone-receptor positive (Medicaid, n = 1156; private, n = 1667).Main Outcomes and MeasuresWe used logistic regression to estimate the likelihood of treatment within 12 months to assess whether the results varied between data sources.ResultsThere were 3392 and 2823 participants in the radiation and hormone therapy cohorts, respectively. The mean (SD) age was 51.71 (8.30) years in the radiation therapy cohort, and 52.00 (8.16) years in the hormone therapy cohort. Among the participants, there were 140 (4%) and 105 (4%) who were Black non-Hispanic, 499 (15%) and 406 (14%) who were Hispanic, 2602 (77%) and 2190 (78%) were White, and 151 (4%) and 122 (4%) were other/unknown in the radiation and hormone therapy cohorts, respectively. A higher percentage of women were aged 50 years or younger in the Medicaid samples (40% vs 34% in the privately insured sample) and identified as non-Hispanic Black (about 7%) or Hispanic (approximately 24%). Treatment was underreported in both sources, but to a lesser extent in the APCD (2.5% and 2.0% for Medicaid and private insurance, respectively) compared with CCCR (19.5% and 13.3% for Medicaid and private insurance, respectively). Using CCCR data, Women with Medicaid insurance were 4 (95% CI, −8 to −1; P = .02) and 10 (95% CI, −14 to −6; P &amp;lt; .001) percentage points less likely to have a record of radiation and hormone therapy compared with privately insured women, respectively. Using combined CCCR and APCD, no statistically significant disparity was observed in radiation or hormone therapy between Medicaid-insured and privately insured women.Conclusions and RelevanceAmong women with breast cancer covered by Medicaid vs private insurance, cancer treatment disparities may be overestimated if based solely on cancer registry data.
Effectiveness of mobile-based intervention Self-care for Pregnant Women at Work: A randomized controlled trial
Authors: Lee Yaelim , Kim Seohyeon , Choi Soeun 
Published: May 2023

Abstract

Objectives
While the number of employed women has increased worldwide, they still have difficulties in practicing prenatal care at work. Previous studies have found that smartphone-based prenatal education has increased access to healthcare and contributed to improving pregnant women’s health. The objective of this study was to evaluate the effectiveness of a mobile-based intervention—Self-care for Pregnant Women at Work (SPWW)—in enhancing the self-care practices of pregnant women who work.

Methods
A randomized repeated measures design was used in the study. The 126 women were randomly assigned to either an intervention group that used the SPWW mobile application for 4 weeks or a control group that used an application that only had surveys. Both groups completed surveys at preintervention, week 2, and week 4 of their participation in the study. The primary study variables were work stress, pregnancy stress, fear of childbirth, pregnancy experience, and health practices in pregnancy.

Results
A total of 116 participants’ data (60 in the intervention group and 56 in the control group) were analyzed. Significant group-by-time interaction effects were noted for pregnancy stress, pregnancy hassles, and health practices in pregnancy. The effect size of the intervention was small to medium for pregnancy stress (d = −0.425), pregnancy uplifts (d = 0.333), pregnancy hassles (d = −0.599), and health practices in pregnancy (d = 0.490).

Conclusions
A mobile-based intervention using a comprehensive health application is effective in pregnant women at work. Developing educational content and methods targeted at this population would be helpful.
Ultrasound‐Assisted Crystallization Enables Large‐Area Perovskite Quasi‐Monocrystalline Film for High‐Sensitive X‐ray Detection and Imaging
Authors: Li Wen‐Guang , Wang Xu‐Dong , Huang Yu‐Hua , Kuang Dai‐Bin 
Published: May 2023

AbstractIn recent years, halide perovskites have shown great application potential in X‐ray detection due to their superior optoelectronic properties and high X‐ray attenuation coefficient. However, large‐area perovskite fabrication for high performance X‐ray detectors remains extremely challenging. Herein, ultrasound‐assisted crystallization combined with the hot‐pressing method is proposed to prepare large‐area (10 cm × 10 cm) and high‐quality quasi‐monocrystalline thick film of a mixed‐cation perovskite MA0.42FA0.58PbI3. The rapid ultrasound‐assisted crystallization provides more homogeneous nucleation, which is essential to the fabrication of large‐area and uniform perovskite microcrystalline film. Furthermore, the post hot‐pressing treatment is implemented to fuse the crystal boundaries, rearrange the crystal grains, and eliminate the voids between crystals, resulting in a quasi‐monocrystalline film. After the hot‐pressing treatment, the carrier mobility and the carrier mobility‐lifetime product increased about 13‐fold (from 1.8 to 23.5 cm2 s−1 V−1) and 18 times (from 8.4 × 10−6 to 1.5 × 10−4 cm2 V−1), respectively. As a result, a high‐performance MA0.42FA0.58PbI3 quasi‐monocrystalline X‐ray detector is achieved with an impressively high sensitivity (1.16 × 106 µC Gyair−1 cm−2) and low detection limit (37.4 nGyair s−1), demonstrating the potential of the ultrasound‐assisted crystallization and hot‐pressing strategy from an industrial perspective.
Interface Charge Characteristics in Polymer Dielectric Contacts: Analysis of Acoustic Approach and Probe Microscopy
Authors: Hu Leiyu , Wang Weiwang , Yu Shixin , Ma Diqin , Lv Jiaju , Zhong Yu , Li Shengtao , Tanaka Yasuhiro , Takada Tatsuo 
Published: May 2023

AbstractInterfaces are essential components in polymer contact systems, which widely exist in electronic devices and power equipment. Interface charge originating from the mismatch of the electronic structure in interfaces is one of the key issues to modify the device performance due to its multifunctional migration and accumulation behaviors. Hence, the detection and analysis of the interface charge characteristics are of great importance to deeply understand the polymer contact system in various devices. This paper presents an overview of recent research progress in the interface charge properties at dielectric interfaces. Based on the theoretical analysis of the MWS polarization and electronic localized states, two typical approaches of discussing the interface charges from micrometer to millimeter are mainly studied. Acoustic method is prevalent in detecting the space charge in various dielectrics. However, owing to its limited resolution (several µm), it is difficult to clarify the charge distributions at the interface with a micro‐scale. Probe microscopy presents a promising technique due to its flexible surface potential detection at a submicron scale. The challenges and prospects of acoustic and probe microscopy methods are discussed in this paper. The advanced techniques of interface charges can promote the development of new energy electronic devices.
Piezoelectric Effect Polyvinylidene Fluoride (PVDF): From Energy Harvester to Smart Skin and Electronic Textiles
Authors: Feng Zhangbin , Zhao Ziquan , Liu Yanan , Liu Yukang , Cao Xianyang , Yu Deng‐Guang , Wang Ke 
Published: May 2023

AbstractWith the great demand for flexible self‐powered sensors and nanogenerators, polyvinylidene fluoride (PVDF) is widely investigated for outstanding piezoelectric and dielectric constant. In the pursuit for increasing β content, electrospinning is exhibited to be an effective method without external high voltage pooling or mechanical stretching and thus is considered a cost‐effective and simple method, because the molecular dipoles in the PVDF can be aligned during the process of electrospinning with high voltage field and stretching. The methods for improving piezoelectric characteristics are briefly introduced in this review, electrospinning fibers including uniaxial fibers, highly aligned fibers, core–shell fibers and Janus fibers are revealed, and research on theoretical modeling is carried out for efficiency in the design of piezoelectric nanogenerator. Last, studies on prospective applications based on electrospun PVDF and its copolymer PVDF‐TrFE, from sensors to smart skin, from energy harvesters to electronic textiles, are being conducted.
Luminescence Nanoprobes for Drug Screening, Pharmaceutical Analysis, and Therapeutic Evaluations
Authors: Li Lanlan , Hu Tao , Guo Jiawei , Zhang Jianxiang 
Published: May 2023

AbstractLuminescence nanoprobes have been extensively investigated for many biomedical applications, ranging from cell/tissue imaging, real‐time monitoring pathophysiological changes, drug discovery, bioassays, image‐guided surgery, and therapeutic evaluations, mainly due to their excellent physicochemical properties such as tailorable size, controlled morphology, and regulatable luminescence performances. In particular, rationally designed luminescence nanoprobes with reasonable functional integration enable pharmacological effect‐based drug screening, quantification of biological/pharmaceutical agents, and monitoring therapeutic responses of different drugs. This review provides an overview of the applications of different types of luminescence nanoprobes in drug discovery and development, involving various nanoprobes for high‐throughput and high‐content drug screening, pharmaceutical analysis, and therapeutic evaluations in cancers, cardiovascular diseases, and other typical inflammatory diseases. Moreover, challenges and future perspectives regarding future applications of luminescence nanoprobes in the drug discovery field are also discussed.