bluuebunny/crossref_metadata_2025_split huggingface dataset:
Supersymmetric quantum mechanics, multiphoton algebras and coherent states
Authors: García-Muñoz Juan D , Fernández C David J , Vergara-Méndez F 
Published: September 2023

Abstract
The multiphoton algebras for one-dimensional Hamiltonians with infinite discrete spectrum, and for their associated kth-order SUSY partners are studied. In both cases, such an algebra is generated by the multiphoton annihilation and creation operators, as well as by Hamiltonians which are functions of an appropriate number operator. The algebras obtained turn out to be polynomial deformations of the corresponding single-photon algebra previously studied in literature. The Barut-Girardello coherent states, which are eigenstates of the annihilation operator, are obtained and their uncertainty relations are explored by means of the associated quadratures.
Study of microwave quantum electrometric sensors via electromagnetically induced transparency in thermal Rydberg atoms
Authors: Iqbal Dar Zubair , Kaur Amanjot , Arora Bindiya , Kaur Paramjit 
Published: September 2023

Abstract
Quantum electrometric sensing properties of a four-level system are theoretically investigated for microwave (MW) field measurement in thermal Rydberg atoms. In the considered system, the phenomenon of electromagnetically induced transparency (EIT) is invoked to study the impact of microwave (MW) field strength on its optical response. The amplitude of the MW electric field is obtained directly by measuring the height and frequency of EIT peaks. Further, for MW frequency measurement, the probe spectra are examined for red and blue MW detuned cases. It is found that the responsiveness of 133Cs for MW electric field as well as frequency is relatively higher than 87Rb. The overall sensitivity of both these atoms can be enhanced by the convenient setting of the system and field parameters.
Coherence monotones of quantum channels based on two generalized quantum relative entropies
Authors: Fan Jiaorui , Wu Zhaoqi , Fei Shao-Ming 
Published: September 2023

Abstract
By using the Choi–Jamiołkowski isomorphism, we propose two classes of coherence monotones of quantum channels based on the unified (r, s)-relative entropy and the sandwiched Rényi relative entropy. Elegant properties of the coherence monotones for quantum channels are explored. Moreover, we present the upper bounds of the coherence monotones and derive the explicit formulas of the coherence monotones for qubit unitary channels.
Application of linear electron Bernstein current drive models in reactor-relevant spherical tokamaks
Authors: Biswas Bodhi , Speirs David , Freethy Simon , Vann Roddy 
Published: September 2023

Abstract
Electron Bernstein current drive (EBCD) systems in spherical tokamaks are sensitive to plasma and launch conditions, and therefore require large parametric scans to optimise their design. One particular bottleneck in the simulation workflow is quasilinear modelling of current drive efficiency. Linear adjoint models are an attractive alternative, offering a

∼

10

3

×

speed-up compared to quasilinear codes. While linear models are well-tested and commonly used for electron cyclotron current drive (ECCD), they have seen little use in EBCD modelling. In this work, variants of the linear model are applied to EBCD and compared to quasilinear results in a reactor-relevant plasma, i.e. Spherical Tokamak for Energy Production (STEP). This comparison reveals it is important to accurately model the collision operator and finite Larmor radius effects in the linear model. When done properly, good agreement is found with quasilinear calculations, at least for normalised minor radii ρ < 0.7 and at low power densities. The power density threshold for quasilinear effects during EBCD is found to be significantly lower than that of ECCD. This is attributed to the much lower group velocity of the electron Bernstein wave (EBW). Thus, the linear model is only valid for EBCD modelling at low power densities (e.g.

≲

1 MW launched EBW power in STEP). This may be satisfied in present-day experimental devices, but certainly not in reactors targeting non-inductive operation.
Effects of stepwise tidal flat reclamation on tidal evolution in the East China and Yellow Sea
Authors: Lim Byoung-Jun , Chang You-Soon , Cho Yang-Ki 
Published: September 2023

Abstract
Because many coastal developments have been continuously occurred in the Yellow and the East China Sea, it is necessary to analyze the effect of persistent topographic change. This study simulated the tidal change in response to stepwise tidal flat reclamation in East China and the Yellow Sea using the MOdelo HIDrodinâmico (MOHID) ocean model. Based on previous studies and historical coastal information maps, we conducted several numerical experiments with reliable coastal topography changes around two areas (Jiangsu Shoalwater and Gyeonggi Bay) from 1990 to 1994 when the most active development took place. The results show that, unlike other components (S2, O1, and K1), the simulated amplitude of the M2 constituent significantly increased with the disappearance of the tidal flat in the Yellow Sea. At the same time, it decreased in the East China Sea. These results are consistent with the quantile regression analysis using observational data. We also found an accumulating effect of tidal energy flux when the reclamation continued, which does not appear in the previous studies. These results indicate persistent man-made tidal flat reclamation in a specific area can cause more remarkable regional tidal changes through tidal energy redistribution and modification.
A Lehmer-type height lower bound for abelian surfaces over function fields
Authors: Looper Nicole , Silverman Joseph 
Published: September 2023

Let

K
K

be an 1-dimensional function field over an algebraically closed field of characteristic

0
0

, and let

A

/

K

A/K

be an abelian surface. Under mild assumptions, we prove a Lehmer-type lower bound for points in

A
(

K
¯

)

A(\overline {K})

. More precisely, we prove that there are constants

C
1

,

C
2

>
0

C_1,C_2>0

such that the normalized Bernoulli-part of the canonical height is bounded below by
\[

h
^

A

B

(
P
)
≥

C
1

[

K
(
P
)
:
K

]

−
2

\hat {h}_A^{\mathbb {B}}(P) \ge C_1\bigl [K(P):K\bigr ]^{-2}

\]
for all points

P
∈

A
(

K
¯

)

P\in {A(\overline {K})}

whose height satisfies

0
>

h
^

A

(
P
)
≤

C
2

0>\hat {h}_A(P)\le {C_2}

.
Using the Behavior Change Wheel to Identify and Understand Key Facilitators and Barriers for Lifestyle Care for Postmenopausal Breast Cancer Survivors: A Delphi-Study
Authors: van Cappellen-van Maldegem Sandra J M , Mols Floortje , Seidell Jacob C , de Kruif Anja , van de Poll-Franse Lonneke V , Hoedjes Meeke 
Published: September 2023

Abstract

Background
Optimal approaches to promote sustained adherence to lifestyle and bodyweight recommendations in postmenopausal breast cancer (PMBC) survivors are lacking.

Purpose
This Delphi-study aims to identify and understand expert-opinion on potential barriers and facilitators for promoting adherence to these lifestyle and bodyweight recommendations in (clinical) care for PMBC survivors, and to determine potential effective intervention strategies.

Methods
The expert panel consisted of oncology Health Care Professionals (HCPs) (N = 57), patient advocates (N = 5), and PMBC survivors (N = 38). They completed three questionnaires: Q1—idea generation; Q2—validation and prioritization; Q3—ranking. The Behavior Change Wheel was used as theoretical framework for analysis. Thematic analysis was applied to identify key overarching themes based on the top-ranked facilitators and barriers. Potential Behavior Change Techniques (BCTs) and intervention strategies were identified using the Behavior Change Technique Taxonomy version 1 and the Behavior Change Wheel.

Results
Eleven core categories of key barriers/facilitators for the promotion of adherence to recommendations for lifestyle and bodyweight among PMBC survivors were identified. For each core category, relevant BCTs and practical potential intervention strategies were selected based on suggestions from the expert panel. These included: increasing knowledge about the link between lifestyle and cancer; enabling self-monitoring of lifestyle behaviors followed by evaluation; offering group lifestyle counseling for PMBC survivors, enhancing social support for favorable lifestyle behaviors; and stimulating multidisciplinary collaboration among HCPs.

Conclusions
Findings provide valuable insight for the development of interventions changing behavior of PMBC survivors and HCPs toward increased healthy lifestyle (support) behavior.
Female state and condition-dependent chemical signaling revealed by male choice of silk trails
Authors: Beyer Michelle , Uludağ Kardelen Özgün , Tuni Cristina 
Published: September 2023

Abstract
Male mate choice is predicted in systems with high costs of mating, as for those with male nuptial gifts and/or sexual cannibalism. We ask whether males of the nuptial gift-giving spider Pisaura mirabilis exert preferences for mates varying in their reproductive potential based on chemical information during mate search. Males were presented with binary trails consisting of silk lines and substrate-borne chemicals deposited while females were walking, from females varying in 1) body condition (high vs. low), 2) developmental state (subadult vs. adult), and 3) mating state (unmated vs. mated). If female chemical signaling co-varies with individual state, we expect males to choose trails of females that are 1) in higher body condition, indicating higher fecundity, 2) adults, which can successfully reproduce, and 3) unmated, to avoid sperm competition. We show that female signaling is condition-dependent, with males being more likely to follow trails of higher body condition females, but not dependent on female mating state. Males also tended to prefer trails of adults over subadults. Choice did not depend on male individual body condition. Our findings suggest costs to chemical signaling in nutritionally deprived females, often considered negligible, and their potential as reliable indicators of individual quality. Selection may favor male preferences for more fecund partners given the energetic investment nuptial gifts entail. Nutritional and reproductive benefits of multiple mating to females and high share of paternity for males, may instead select against signaling of female mating state, and/or male discrimination and choice.
A scan of all coding region variants of the human genome, identifies 13q12.2-rs9579139 and 15q24.1-rs2277598 as novel risk loci for pancreatic ductal adenocarcinoma
Authors: Giaccherini Matteo , Gori Leonardo , Gentiluomo Manuel , Farinella Riccardo , Cervena Klara , Skieceviciene Jurgita , Dijk Frederike , Capurso Gabriele , Vezakis Antonis , Archibugi Livia , Chammas Roger , Hussein Tamás , Tavano Francesca , Hegyi Péter , Lovecek Martin , Izbicki Jakob R , Brenner Hermann , Mohelnikova-Duchonova Beatrice , Dell’Anna Giuseppe , Kupcinskas Juozas , Ermini Stefano , Aoki Mateus Nóbrega , Neoptolemos John P , Gazouli Maria , Pasquali Claudio , Pezzilli Raffaele , Talar-Wojnarowska Renata , Oliverius Martin , Al-Saeedi Mohammed , Lucchesi Maurizio , Furbetta Niccolò , Carrara Silvia , van Eijck Casper H J , Maleckas Almantas , Milanetto Anna Caterina , Lawlor Rita T , Schöttker Ben , Boggi Ugo , Morelli Luca , Ginocchi Laura , Ponz de Leon Pisani Ruggero , Sperti Cosimo , Zerbi Alessandro , Arcidiacono Paolo Giorgio , Uzunoglu Faik G , Bunduc Stefania , Holleczek Bernd , Gioffreda Domenica , Małecka-Wojciesko Ewa , Kiudelis Mindaugas , Szentesi Andrea , van Laarhoven Hanneke W M , Soucek Pavel , Götz Mara , Erőss Bálint , Cavestro Giulia Martina , Basso Daniela , Perri Francesco , Landi Stefano , Canzian Federico , Campa Daniele 
Published: September 2023

Abstract
Coding sequence variants comprise a small fraction of the germline genetic variability of the human genome. However, they often cause deleterious change in protein function and are therefore associated with pathogenic phenotypes. To identify novel pancreatic ductal adenocarcinoma (PDAC) risk loci, we carried out a complete scan of all common missense and synonymous SNPs and analysed them in a case–control study comprising four different populations, for a total of 14 538 PDAC cases and 190 657 controls. We observed a statistically significant association between 13q12.2-rs9581957-T and PDAC risk (P = 2.46 × 10−9), that is in linkage disequilibrium (LD) with a deleterious missense variant (rs9579139) of the URAD gene. Recent findings suggest that this gene is active in peroxisomes. Considering that peroxisomes have a key role as molecular scavengers, especially in eliminating reactive oxygen species, a malfunctioning URAD protein might expose the cell to a higher load of potentially DNA damaging molecules and therefore increase PDAC risk. The association was observed in individuals of European and Asian ethnicity. We also observed the association of the missense variant 15q24.1-rs2277598-T, that belongs to BBS4 gene, with increased PDAC risk (P = 1.53 × 10−6). rs2277598 is associated with body mass index and is in LD with diabetes susceptibility loci. In conclusion, we identified two missense variants associated with the risk of developing PDAC independently from the ethnicity highlighting the importance of conducting reanalysis of genome-wide association studies (GWASs) in light of functional data.
Mussel mass mortality in the Clinch River, USA: metabolomics detects affected pathways and biomarkers of stress
Authors: Putnam Joel G , Steiner John N , Richard Jordan C , Leis Eric , Goldberg Tony L , Dunn Christopher D , Agbalog Rose , Knowles Susan , Waller Diane L 
Published: September 2023

AbstractBiologists monitoring freshwater mussel (order Unionida) populations rely on behavioral, often subjective, signs to identify moribund (“sick”) or stressed mussels, such as gaping valves and slow response to probing, and they lack clinical indicators to support a diagnosis. As part of a multi-year study to investigate causes of reoccurring mortality of pheasantshell (Ortmanniana pectorosa; synonym Actinonaias pectorosa) in the Clinch River, Virginia and Tennessee, USA, we analyzed the hemolymph metabolome of a subset of mussels from the 2018 sampling period. Mussels at the mortality sites were diagnosed in the field as affected (case) or unaffected (control) based on behavioral and physical signs. Hemolymph was collected in the field by non-lethal methods from the anterior adductor muscle for analysis. We used ultra-high-performance liquid chromatography with quadrupole time-of-flight mass spectroscopy to detect targeted and untargeted metabolites in hemolymph and compared metabolomic profiles by field assessment of clinical status. Targeted biomarker analysis found 13 metabolites associated with field assessments of clinical status. Of these, increased gamma-linolenic acid and N-methyl-l-alanine were most indicative of case mussels, while adenine and inosine were the best indicators of control mussels. Five pathways in the targeted analysis differed by clinical status; two of these, purine metabolism and glycerophospholipid metabolism, were also indicated in the untargeted analysis. In the untargeted nalysis, 22 metabolic pathways were associated with clinical status. Many of the impacted pathways in the case group were catabolic processes, such as degradation of amino acids and fatty acids. Hierarchical clustering analysis matched clinical status in 72% (18 of 25) of mussels, with control mussels more frequently (5 of 16) not matching clinical status. Our study demonstrated that metabolomic analysis of hemolymph is suitable for assessing mussel condition and complements field-based indicators of health.
Non-invasive myocardial work in aortic stenosis: validation and improvement in left ventricular pressure estimation
Authors: Ribic Darijan , Remme Espen W , Smiseth Otto A , Massey Richard J , Eek Christian H , Kvitting John-Peder Escobar , Gullestad Lars , Broch Kaspar , Russell Kristoffer 
Published: September 2023

Abstract

Aims
The non-invasive myocardial work index (MWI) has been validated in patients without aortic stenosis (AS). A thorough assessment of methodological limitations is warranted before this index can be applied to patients with AS.

Methods and results
We simultaneously measured left ventricular pressure (LVP) by using a micromanometer-tipped catheter and obtained echocardiograms in 20 patients with severe AS. We estimated LVP curves and calculated pressure–strain loops using three different models: (i) the model validated in patients without AS; (ii) the same model, but with pressure at the aortic valve opening (AVO) adjusted to diastolic cuff pressure; and (iii) a new model based on the invasive measurements from patients with AS. Valvular events were determined by echocardiography. Peak LVP was estimated as the sum of the mean aortic transvalvular gradient and systolic cuff pressure. In same-beat comparisons between invasive and estimated LVP curves, Model 1 significantly overestimated early systolic pressure by 61 ± 5 mmHg at AVO compared with Models 2 and 3. However, the average correlation coefficients between estimated and invasive LVP traces were excellent for all models, and the overestimation had limited influence on MWI, with excellent correlation (r = 0.98, P &lt; 0.001) and good agreement between the MWI calculated with estimated (all models) and invasive LVP.

Conclusion
This study confirms the validity of the non-invasive MWI in patients with AS. The accuracy of estimated LVP curves improved when matching AVO to the diastolic pressure in the original model, mirroring that of the AS-specific model. This may sequentially enhance the accuracy of regional MWI assessment.
Gender-affirming treatment and mental health diagnoses in Danish transgender persons: a nationwide register-based cohort study
Authors: Glintborg Dorte , Møller Jens-Jakob Kjer , Rubin Katrine Hass , Lidegaard Øjvind , T’Sjoen Guy , Larsen Mie-Louise Julie Ørsted , Hilden Malene , Andersen Marianne Skovsager 
Published: September 2023

AbstractImportanceGender affirming treatment aims to improve mental health.ObjectiveTo investigate longitudinal mental health outcomes in Danish transgender persons.DesignNational register-based cohort study in Danish transgender persons with diagnosis code of “gender identity disorder” during the period 2000-2021.ParticipantsFive age-matched controls of the same sex at birth and five age-matched controls of the other sex at birth were included for each transgender person.Main outcomesDiagnosis codes of mental and behavioral disorders and/or prescription of psychopharmacological agents until June 2022.ResultsThe cohort included 3812 transgender persons with median age (interquartile range) 19 (15; 24) years for persons assigned female at birth (AFAB, N = 1993) and 23 (19; 33) years for persons assigned male at birth (AMAB, N = 1819) and 38 120 controls. Follow up duration was up to 10 years with mean (standard deviation) 4.5 (4.3) years. In transgender persons AFAB compared to control women, the odds ratio (OR) (95% confidence interval) for mental and behavioral disorders was 6.7 (5.5; 8.1) before the index date, 9.9 (8.4; 11.7) at 1 year, 5.8 (4.4; 7.7) at 5 years, and 3.4 (2.1; 7.5) at 8 years follow up. In transgender persons AMAB compared to control men, corresponding ORs were 5.0 (4.0; 6.4), 11.3 (9.3; 13.7), 4.8 (3.5; 6.5), and 6.6 (4.2; 10.3) at 8 years follow up (all P &lt; .001).ConclusionThe OR for mental health disorders was higher in transgender persons compared to controls and remained elevated throughout follow up, especially in transgender persons AMAB.
Situated socio-material assemblages: assemmethodology in the making
Authors: Due Brian L 
Published: September 2023

Abstract
This article proposes the concept of assemmethodology, which combines assemblage theory and ethnomethodology. Relating to the ongoing studies in sociomateriality, this article advances our understanding of the details of social conduct and the consequentiality of materials. By explicating the role of the situation and its processual becoming, which is inherent in ethnomethodology, and by replacing the unit of analysis from the individual to the assemblage made up of heterogenous elements, this article contributes to communication research that seeks to advance our understanding of the ways in which humans are entangled with the material world. As a perspicuous case for the study of assemmethodology, this article explores situations in which screens are assembled with humans and other materials in social situations. The article uses these examples to highlight the necessity of maintaining a focus on the situated emergence of socio-material orders as a property of the activity.
Genes positively regulated by Mef2c in cortical neurons are enriched for common genetic variation associated with IQ and educational attainment
Authors: Fahey Laura , Ali Deema , Donohoe Gary , Ó Broin Pilib , Morris Derek W 
Published: September 2023

AbstractThe myocyte enhancer factor 2 C (MEF2C) gene encodes a transcription factor important for neurogenesis and synapse development and contains common variants associated with intelligence (IQ) and educational attainment (EA). Here, we took gene expression data from the mouse cortex of a Mef2c mouse model with a heterozygous DNA binding-deficient mutation of Mef2c (Mef2c-het) and combined these data with MEF2C ChIP-seq data from cortical neurons and single-cell data from the mouse brain. This enabled us to create a set of genes that were differentially regulated in Mef2c-het mice, represented direct target genes of MEF2C and had elevated in expression in cortical neurons. We found this gene-set to be enriched for genes containing common genetic variation associated with IQ and EA. Genes within this gene-set that were down-regulated, i.e. have reduced expression in Mef2c-het mice versus controls, were specifically significantly enriched for both EA and IQ associated genes. These down-regulated genes were enriched for functionality in the adenylyl cyclase signalling system, which is known to positively regulate synaptic transmission and has been linked to learning and memory. Within the adenylyl cyclase signalling system, three genes regulated by MEF2C, CRHR1, RGS6, and GABRG3, are associated at genome-wide significant levels with IQ and/or EA. Our results indicate that genetic variation in MEF2C and its direct target genes within cortical neurons contribute to variance in cognition within the general population, and the molecular mechanisms involved include the adenylyl cyclase signalling system’s role in synaptic function.
Software Application Profile:dynamicLM—a tool for performing dynamic risk prediction using a landmark supermodel for survival data under competing risks
Authors: Fries Anya H , Choi Eunji , Wu Julie T , Lee Justin H , Ding Victoria Y , Huang Robert J , Liang Su-Ying , Wakelee Heather A , Wilkens Lynne R , Cheng Iona , Han Summer S 
Published: September 2023

AbstractMotivationProviding a dynamic assessment of prognosis is essential for improved personalized medicine. The landmark model for survival data provides a potentially powerful solution to the dynamic prediction of disease progression. However, a general framework and a flexible implementation of the model that incorporates various outcomes, such as competing events, have been lacking. We present an R package, dynamicLM, a user-friendly tool for the landmark model for the dynamic prediction of survival data under competing risks, which includes various functions for data preparation, model development, prediction and evaluation of predictive performance.ImplementationdynamicLM as an R package.General featuresThe package includes options for incorporating time-varying covariates, capturing time-dependent effects of predictors and fitting a cause-specific landmark model for time-to-event data with or without competing risks. Tools for evaluating the prediction performance include time-dependent area under the ROC curve, Brier Score and calibration.AvailabilityAvailable on GitHub [https://github.com/thehanlab/dynamicLM].