bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Impact of Corporate Communication on Consumer Psychology and Product Choice
Authors: Zhong Shuai , Ji Chunli , Prentice Catherine , Yang Jianchun , Li Yuan 
Published: January 2025

ABSTRACTThis research investigates the influence of corporate ability (CA) and social responsibility (CSR) on consumers' product choices through three experimental studies. In Experiment 1, using a real company as the experimental stimulus with 134 participants, we found that for utilitarian products, CA messages had a more substantial influence on purchase intention compared to CSR messages. Experiment 2, employing a fictitious company and products with 142 participants, uncovered significant mediation effects of product trust and product pleasure on the relationship between corporate messages (CA and CSR) and purchase intention for both utilitarian and hedonic products. Experiment 3, with 268 participants, substantiated that product involvement significantly moderates the influence of corporate messages (CA and CSR) on purchase intention for both utilitarian and hedonic products. The findings reveal that CA messages have stronger effects on the purchase of utilitarian products, whereas CSR messages are more effective for hedonic products. Trust significantly mediates the relationship between CA and the purchase of utilitarian products, while pleasure mediates the relationship between CSR and the purchase of hedonic products. Additionally, product involvement significantly moderates these effects. This study uniquely addresses the distinct impacts of CA and CSR on consumer choices, offering valuable insights for corporate communication strategies. The results provide practical implications for marketers, suggesting tailored communication strategies based on product type and consumer involvement.
Optimised Synthesis of Rhombic dodecahedral Cu2O Nanoparticles: A Pathway to Superior Morphological Control
Authors: Sarasino Lorenzo , Ohno Teruhisa , Cristina Paganini Maria 
Published: January 2025

AbstractCuprous oxide (Cu2O) nanoparticles hold significant promise for photocatalytic applications due to their narrow bandgap and high surface reactivity. This study focuses on the synthesis of rhombic dodecahedral Cu2O (RD‐Cu2O) nanoparticles, totally enclosed by {110} facets, known to exhibit superior photocatalytic performance over the other low‐index crystallographic facets. The precise control over the synthesis conditions can significantly enhance the exposure of this highly active face and therefore improve the catalytic performance of Cu2O nanoparticles, making them superior for applications in pollutant degradation, organic reactions, and artificial photosynthesis. We systematically optimised the synthesis parameters, including reactants concentration, pH and other reaction conditions, to achieve a significant scale up of well‐defined RD‐ Cu2O nanoparticles production, strictly necessary for the use of this photocatalyst on a larger scale. The optimised and scaled up synthesis require 2.0 mmol of CuCl2, 6.0 mmol of Sodium dodecyl sulphate (SDS), 9.6 mmol of NH2OH ⋅ HCl and 7.0 mmol of NaOH added in this order to 400 ml of water at 25 °C. The optimised nanoparticles demonstrated a narrow size distribution and a high degree of crystallographic control. Characterisation techniques such as FESEM, XRD, EPR, UV‐Vis spectroscopy, and XPS confirmed the improved morphological and structural properties of the synthesised RD‐Cu2O nanoparticles.
Toxicity and Quality of Life After Locoregional Radiotherapy in Patients With Thyroid Cancer
Authors: van den End Job W. , Jager Eline C. , Verbeek Hans H. G. , Oldehinkel Edwin , Jansen Liesbeth , Brouwers Adrienne H. , Zandee Wouter T. , Kruijff Schelto , Links Thera P. 
Published: January 2025

ABSTRACTBackgroundLocoregional external beam radiotherapy (EBRT) is selectively used in thyroid cancer patients to induce locoregional control. However, despite technological advances, EBRT remains associated with toxicities. We evaluated thyroid‐cancer specific toxicities and long‐term Quality of Life (QoL) post‐EBRT.MethodsEBRT‐treated thyroid cancer patients at Universal Medical Centre Groningen (2007–2023) were retrospectively evaluated (n = 66). Acute (< 6 weeks) and late (≥ 3 months) toxicities and QLQ‐H&N35 results, prospectively collected as standard patient care, were analyzed (available in 24/66). Additionally, 17/66 living patients cross‐sectionally completed the QLQ‐H&N43 [renewed QLQ‐H&N35] and SF‐36‐RAND‐36.ResultsIn 24/66 patients who completed questionnaires during EBRT treatment, most severe acute toxicities occurred around week 6 (91% dermatitis, 74% pain, 70% hoarseness, 65% dysphagia). Late toxicities included persisting acute toxicities and fibrosis. Six months post‐treatment, only QLQ‐H&N35 domains “social eating” (p = 0.031) and “dry mouth/sticky saliva” (p = 0.025) were affected, in comparison to pre‐radiation. In the 10/17 patients who completed the QLQ‐H&N35 6 months post‐radiation and the cross‐sectionally performed QLQ‐H&N43, no long‐term mitigation of assessed domains was identified in a longitudinal analysis. The most advanced EBRT technique was associated with better QLQ‐H&N43 scores (p = 0.047).ConclusionsEBRT causes acute and late toxicities in most thyroid cancer patients and may be associated with a decreased QoL. As these patients generally survive for multiple years, there is a compelling need to minimize toxicities with more refined radiation techniques, such as proton therapy.
Video urodynamic findings pre‐and post‐transurethral holmium laser enucleation of the prostate for small benign prostatic hyperplasia with vesicoureteral reflux
Authors: Teramoto Sakiko , Murase Kazumasa , Kurosawa Nagayuki , Nagai Shingo , Kubota Yasuaki 
Published: January 2025

IntroductionWe report the pre‐and postoperative evaluation of small benign prostatic hyperplasia with secondary vesicoureteral reflux using video urodynamics.Case presentationA 57‐year‐old man had been suffering from urinary dysfunction for 10 years and was aware of discomfort in his right back during urination. A prostate volume was 24 mL. Cystoscopy revealed hypertrophy of the middle lobe. Video urodynamics demonstrated storage dysfunction, voiding dysfunction, and Grade 3 right vesicoureteral reflux. We performed transurethral holmium laser enucleation of the prostate. Video urodynamics demonstrated improvements in both storage and voiding functions, and the right vesicoureteral reflux resolved 6 months postoperatively.ConclusionEven a small prostate can cause severe urinary dysfunction. In cases of secondary vesicoureteral reflux associated with bladder outlet obstruction, simultaneous repair of the reflux is not necessary unless there is recurrent pyelonephritis or reflux nephropathy.
Parents’ reflective functioning and stress: The associations with preschoolers’ social understanding
Authors: Longobardi Emiddia , Morelli Mara , Brunetti Matilde , Sette Stefania , Spataro Pietro , Laghi Fiorenzo 
Published: January 2025

AbstractSocial understanding competence develops in sensitive and co‐regulating caregiver interactions. Parental reflective functioning (PRF) and parenting stress can affect children's social understanding. This study investigated if children's social understanding was associated with PRF and parenting stress. Parents of 305 Italian children aged from 24 to 72 months (M = 48.2, SD = 13.9; 47.9% girls) completed an online survey. Parents completed the following questionnaire: The Parenting Stress Index—Short Form, the Parental Reflective Functioning Questionnaire, and the Children's Social Understanding Scale. Results showed that children's social understanding was predicted by lower parenting stress, b = .002, p = .017, and parent's interest and curiosity about the child's mental states, b = .07, p = .013. Findings confirm that high levels of parenting stress and low PRF constitute unfavorable conditions for preschoolers’ socio‐cognitive development. Thus, the present study can have implication for interventions aimed at improving children's social understanding that should focus on reducing parenting stress and enhancing parental mentalizing.
Enhancing Insight in Patients With Obsessive Compulsive Disorder: A Case Study on Avatar Therapy Using Virtual Reality
Authors: Wille Lara , Lohse Luzie , Jelinek Lena , Moritz Steffen , Schultz Josephine , Borsutzky Swantje , Yassari Amir H. , Mariegaard Lise , Vernal Ditte Lammers , Bekker Sanne Helene , Glenthøj Louise Birkedal , Miegel Franziska 
Published: January 2025

ABSTRACTTreatment efficacy for patients with obsessive‐compulsive disorder (OCD) with poor insight is low. Insight refers to a patient's ability to recognize that their obsessions are irrational and that their compulsions are futile attempts to reduce anxiety. This case study presents the first application of virtual reality‐assisted avatar therapy for OCD (VRT‐OCD) in a patient with contamination OCD and ambivalent insight. Before treatment, the patient was not distanced from the content of his obsessions, which obstructed treatment progress. VRT‐OCD aims to enhance insight by creating distance between the patient's functional self and their OCD by means of a virtual avatar, an individually designed visual representation of their OCD. The three‐session therapy involved engaging with the avatar, practicing resistance to the OCD, and reinforcing self‐esteem based on the patient's values. By learning that his obsessions hindered him from living life according to his values, the patient was motivated to engage in dialog with his avatar and learned to stand up for himself. After treatment, the patient had improved insight (BABS score reduced by 71%) and reduced symptoms (Y‐BOCS score reduced by 51%). First results suggest that VRT‐OCD may increase insight and empower patients to confront their obsessions, leading to increased motivation to resist their compulsions. This study highlights the feasibility, acceptance, and potential effectiveness of VRT‐OCD as a novel therapeutic approach for individuals with OCD.
Drug–Drug Interaction Between Rifampicin and Albuvirtide: A Phase 1, Randomized, Open‐Label Study
Authors: Zhang Li , Chen Jun , Lin Xiao‐Yan , Lu Yan , Wu Yan , Wu Yi‐Jun , Meng Xian‐Min 
Published: January 2025

AbstractAlbuvirtide (ABT) is a novel long‐acting fusion inhibitor for human immunodeficiency virus type 1 (HIV‐1), and may be co‐administered with rifampicin (RIF) in patients concurrent with tubercle bacillus and HIV‐1. This study was conducted to investigate the pharmacokinetic effect of co‐administration of the two drugs. In the study, 24 healthy volunteers were randomized to receive ABT alone or with RIF. Plasma concentrations were measured using liquid chromatography‐tandem mass spectrometry for RIF and competitive enzyme‐linked immunosorbent assay for ABT. Co‐administration with RIF increased the maximum concentration (Cmax) of ABT by 6.93%, and the area under the plasma concentration–time curve (AUC) from time 0 to the last quantifiable concentration (AUC0–t) by 21.31%; the geometric mean ratio values (GMRs) for Cmax and AUC0–t of ABT when co‐administered with RIF, relative to administered alone, were 106.93% (90% confidence interval [CI] 97.53%–117.23%) and 121.31% (90% CI 108.68%–135.40%), respectively. Co‐administration with ABT decreased the steady‐state Cmax (Cmax,ss) of RIF by 10.19%, and the steady‐state AUC from time 0 to 24 h (AUC0–24 h,ss) by 19.93%; the GMRs for Cmax,ss and AUC0–24 h,ss of RIF when co‐administered with ABT, relative to administered alone, were 89.81% (90% CI, 79.97%–104.79%) and 80.07% (90% CI 75.68%–84.72%), respectively. The time to reach Cmax (Tmax) of both ABT and RIF demonstrated no statistically significant difference, whether administered alone or concurrently. The pharmacokinetics profiles of both RIF and ABT changed to some extent when co‐administered, while no clinically significant impact on these two drugs was observed, indicating that ABT and RIF can be used together without necessitating dose adjustments.
Examining the Impact of Diet‐and‐Exercise‐Induced Weight Loss on Drug Metabolism and Gastric Emptying in Patients with Obesity
Authors: Liu Shuhan , Wang Lu , Miller Nicole , Waltje Andrea , Abdelnabi Mohamed , Zhu Hao‐Jie , Sun Duxin , Rothberg Amy E. , Pai Manjunath P. 
Published: January 2025

AbstractObesity significantly influences drug pharmacokinetics (PK), which challenges optimal dosing. This study examines the effects of diet‐and‐exercise‐induced weight loss on key drug‐metabolizing enzymes and gastric emptying in patients with obesity, who frequently require medications for comorbidities. Participants followed a structured weight management program promoting weight loss over 3–6 months and were not concomitantly on potential CYP inducers or inhibitors. Using a drug cocktail of acetaminophen, caffeine, omeprazole, and midazolam, we assessed UGT1A1, CYP1A2, CYP2C19, and CYP3A4 enzyme activities before and after weight loss, respectively, by measuring parent and metabolite concentrations. The time to maximum acetaminophen plasma concentrations reflected the gastric emptying time. PK profiles were compared across two phases: baseline (Phase 1) and post‐weight loss (Phase 2). Twenty‐four participants enrolled, 21 completed Phase 1 and 12 completed both phases. Statistically significant (N = 12, P < .05) gains in CYP2C19 and CYP3A4 activity were observed after weight loss of 7.6% to 26.2%, with a median [25th, 75th percentile] increase in activity of 90.5 [15.0, 194.3] % and 43.0 [7.5, 68.0] %, respectively. A 2‐ or 3‐h single plasma sample‐based ratio of the metabolite to parent concentration strongly correlated with the respective AUC ratio for the drug metabolism phenotype (N = 21). Our findings provide provisional data for evaluation of the effects of non‐pharmacologically and non‐surgically induced weight loss on gastric emptying and drug metabolism for future physiologically based PK models. Development of mechanistic models to optimize drug dosing in obesity are necessary since weight and body composition shifts are expected with emerging new treatments.
Functional outcome improvement and surgical time reduction in a single‐surgeon consecutive case series of hip arthroscopy for femoroacetabular impingement: A minimum 5 years follow‐up study
Authors: Tassinari Enrico , Caternicchia Filippo , Rosa Mattia D. , Castagnini Francesco , Angeletti Edoardo , Fantoni Valentina , Tampieri Irene , Burla Andrea , Zaffagnini Stefano 
Published: January 2025

AbstractPurposeThe learning curve of a single surgeon performing hip arthroscopy is reported to be steep, but, to date, the inflection point after which procedures are more successful is still unknown. The aim of this study was to design a learning curve focused on clinical outcomes, complications and revision/conversion rates.MethodsSeventy‐one hip arthroscopies performed for femoroacetabular impingement (FAI) by a single surgeon, with a minimum follow‐up of 5 years, were considered. Demographics, intraarticular findings and operative and traction time were detailed. HOOS score, subjective outcomes, 30‐day complication rates, complication rates, revision arthroscopies and conversions to hip arthroplasty were recorded.ResultsThe mean follow‐up was 7.5 ± 1.8 years (range: 5–11). The progression of the learning curve implied a reduction in surgical time (r: −0.847), traction time (r: −0.806) and postoperative outcomes (r = 0.444). When the procedures were divided into three consecutive groups (25 vs. 25 vs. 21 procedures) or two consecutive groups (36 vs. 35 cases), the first group had a higher occurrence of 30‐day complications (p = 0.002 and p = 0.025, respectively) and the last group experienced a significant amelioration in terms of HOOS score between the preoperative and the postoperative condition (p < 0.001 and p = 0.018).ConclusionsThe inflection point of the hip arthroscopy learning curve is between 25/36 procedures. The first arthroscopies were impacted by higher complications and lower clinical results but no higher rates of revision and conversion to arthroplasty.Level of EvidenceLevel IV.
Recent advances in the management of pediatric cholestatic liver diseases
Authors: Mysore Krupa R. , Cheng Katherine , Suri Lakshmi Anandini , Fawaz Rima , Mavis Alisha M. , Kogan‐Liberman Debora , Mohammad Saeed , Taylor Sarah A. 
Published: January 2025

AbstractPediatric cholestatic liver diseases are rare conditions that can result from multiple specific underlying etiologies. Among the most common etiologies of pediatric cholestatic liver diseases are biliary atresia, Alagille syndrome (ALGS), and inherited disorders of bile acid transport. These diseases are characterized by episodic or chronic unremitting cholestasis. Due to the chronicity of these conditions, it is imperative to optimize medical management to improve patient quality of life, provide nutritional support, and reduce bile acid toxicity in efforts to slow disease progression. Cholestatic liver diseases remain the leading cause of pediatric liver transplantation, as many underlying disease etiologies have no curative medical therapies. In the present review, we provide an update on the nutritional, medical, and surgical management of pediatric cholestatic liver diseases. As recent advances have occurred in the field with the addition of ileal bile acid transporter (IBAT) inhibitors, we also review the results from prospective clinical trials, including their strengths and limitations. While recent clinical trials have demonstrated improved pruritus using IBAT inhibitors in ALGS and progressive familial intrahepatic cholestasis, establishing medical therapies proven to slow disease progression remains an area of unmet need.
Dynamic high‐pressure microfluidization for the extraction and processing of polysaccharides: a focus on some foods and by‐products
Authors: Zhang Yang , Yang Jingchun , Ling Yuchun , Liu Yaqi , Chen Kun , Shen Yingchao , Zhou Yuan , Luo Bing 
Published: January 2025

AbstractDynamic high‐pressure microfluidization (DHPM) is an emerging treatment technology and has been widely used for the recovery of natural polysaccharides. The aim of the present contribution is to discuss the DHPM‐assisted extraction and processing of polysaccharides from some foods and by‐products by reviewing the instrument and working principle, procedures, key parameters, and effects of DHPM on the structures, food properties, and bioactivities of resulting polysaccharides. It was found that a DHPM instrument with Z‐type chamber is preferable for extracting polysaccharides, and a DHPM with Y‐type chamber is applicable for processing polysaccharides. The solid‐to‐liquid ratio (or concentration), pressure, and number of passes are the key parameters influencing the outcome of DHPM extraction and processing. The DHPM under suitable conditions is conducive to boosting the extraction yields of polysaccharides, enriching the carbohydrates and uronic acids in polysaccharides, lowering the protein impurities, and transforming insoluble dietary fibers into soluble ones. In most cases, DHPM treatment improved the food properties of polysaccharides via decreasing viscosity, molecular weight, and particle size, as well as losing the surface morphology. More importantly, DHPM is a mild treatment technique that barely affects the chain backbones of polysaccharides. DHPM‐assisted extraction and processing endowed polysaccharides with enhanced antioxidant, hypolipidemic, and hypoglycemic activities, exhibiting potential for the treatment of cardiovascular disease. In addition, DHPM‐treated polysaccharides exerted certain potential in whitening cosmetics via inhibiting tyrosinase. In conclusion, DHPM is a mild, efficient, and green technology to recover and modify polysaccharides from natural resources, especially foods and by‐products. © 2025 Society of Chemical Industry.
Over 1500 PPI quantum dot color conversion array by lift‐off
Authors: Song Qi , Ma Jingrui , Li Depeng , Li Chengcheng , Liu Pai , Sun Xiao Wei 
Published: January 2025

AbstractThis study explores the application of lift‐off process for the patterning of quantum dot (QD) pixels using CdSe/ZnS core‐shell colloidal QDs. The evaluation of the influence of different solvent and binder systems on the effectiveness of the pixelation is detaily discussed. By optimizing the solvent and binder combination, the fabrication of multi‐color QD patterns with pixel sizes ranging from 5 to 200 μm were demonstrated, achieving blue light conversion efficiencies exceeding 18% and 25% for red and green pixels. It is also improved pixel uniformity, stability, and resolution, lying the foundation for the development of ultra‐high‐resolution, QD Micro‐LED display. However, challenges remain in maximizing the utilization of blue light and packaging of QD layers. Future research will aim to develop high‐quality QD inks suitable for photoresist lift‐off and optimize the QD Micro‐LED system to further enhance the performance and stability of QD‐based displays.
Colorectal Cancer Surgery at a Regional Cold Site Centre During the SARS‐CoV‐2 Pandemic: A Comparison With Prepandemic Practices
Authors: Soop Mattias , Anderin Kajsa , Syk Erik , Nygren Jonas , Segelman Josefin 
Published: January 2025

ABSTRACTIntroductionStockholm, Sweden had among the highest excess mortality rates during the first wave of the SARS‐CoV‐2 pandemic. In March 2020, an entire hospital implemented an infection‐free cold site infrastructure and scaled up imperative mainly colorectal cancer surgery, for the Stockholm health care region. The study evaluated the efficacy of the concept.MethodsStrict preadmission screening and prophylactic interventions were implemented. The outcomes of the cold site cohort (30th March–21st June 2020) were compared to a prepandemic control. Population‐based data on colorectal cancer patients were collected from the Swedish Colorectal Cancer Registry.ResultsThere were 107 patients in the cold site cohort and 109 in the control cohort. None developed COVID‐19 within 30 days postoperatively. The proportions of pelvic and laparoscopic surgery were similar. The cold site cohort had more potentially avoidable stomas (32/94 (34%) vs 19/91 (21%), p = 0.0442). In the region, the proportion of colorectal cancer resections at the cold site increased from prepandemic 12.9% (58 of 448) to 43.3% (94 of 217) (p < 0.001).ConclusionA SARS‐CoV‐2‐cold site can be kept infection‐free by screening, allowing increased volumes of colorectal cancer surgery with outcomes comparable to prepandemic practice. The cold site model should be more widely adopted in future similar scenarios.SummaryThis study reports on the implementation of an entire cold site hospital for imperative colorectal surgery, in particular colorectal cancer, during the SARS‐CoV‐2 pandemic. By comparing outcomes to prepandemic practices, we demonstrated that the cold site hospital was effective in preventing infection and safely increasing surgical volume many‐fold.