bluuebunny/crossref_metadata_2025_split huggingface dataset:
The role of polygenic risk scores in breast cancer risk perception and decision-making
Authors: Riddle Leslie , Joseph Galen , Caruncho Mikaella , Koenig Barbara Ann , James Jennifer Elyse 
Published: June 2023

AbstractPolygenic risk scores (PRS) have the potential to improve the accuracy of clinical risk assessments, yet questions about their clinical validity and readiness for clinical implementation persist. Understanding how individuals integrate and act on the information provided by PRS is critical for their effective integration into routine clinical care, yet few studies have examined how individuals respond to the receipt of polygenic risk information. We conducted an embedded Ethical, Legal, and Social Implications (ELSI) study to examine if and how unaffected participants in a US population breast cancer screening trial understood and utilized PRS, as part of a multifactorial risk score combining traditional risk factors with a genetic risk assessment, to make screening and risk-reduction decisions. Semi-structured qualitative interviews were conducted with 24 trial participants who were designated at elevated risk for breast cancer due to their combined risk score. Interviews were analyzed using a grounded theory approach. Participants understood PRS conceptually and accepted it as one of many risk factors to consider, yet the value and meaning they ascribed to this risk estimate varied. Most participants reported financial and insurance barriers to enhanced screening with MRI and were not interested in taking risk-reducing medications. These findings contribute to our understanding of how PRS may be best translated from research to clinical care. Furthermore, they illuminate ethical concerns about identifying risk and making recommendations based on polygenic risk in a population screening context where many may have trouble accessing appropriate care.
How current perspectives on algorithmic thinking can be applied to students’ engagement in algorithmatizing tasks
Authors: Lehmann Timothy H. 
Published: June 2023

AbstractThe aim of this study is to examine how algorithmatizing tasks engage mathematics students in algorithmic thinking. Structured, task-based interviews were conducted with eight Year 12 students as they completed a sequence of algorithmatizing tasks involving maximum flow problems. A deductive-inductive analytical process was used to first classify students’ mathematical behavior according to four cognitive skills of algorithmic thinking (decomposition, abstraction, algorithmization, and debugging) and then develop sets of subskills to describe how the students engaged these cognitive skills. The findings show how students used algorithmic thinking to solve maximum flow problems and then made progress towards creating a general algorithm before being introduced to the maximum-flow minimum-cut approach, which guarantees a solution.
Building research capacity at FQHCs: A model of support from the All of Us Research Program
Authors: Inokuchi Derek , Mehta Heta K. , Burke Jessica M. 
Published: June 2023

Abstract
The All of Us Research Program is an historic effort to gather data over 10+ years from one million or more people living in the United States to accelerate research and advance precision medicine. There is a particular focus on populations historically underrepresented in biomedical research who are often served by Federally Qualified Health Centers (FQHCs). However, FQHCs face significant challenges in participating in research. This paper addresses three common barriers faced by FQHCs and describes a management model that was used to support a group of FQHCs participating in the All of Us Research Program. Specifically, the paper addresses the challenges of building FQHC research capacity to operationalize and manage research activities, transforming and sharing Electronic Health Records and other data, and recruiting and retaining research participants. The central coordination management model, which was used to support the FQHCs, is a generalizable framework and can serve as an exemplar of how to engage FQHCs in other longitudinal research efforts. To date, the FQHCs have enrolled more than 10,000 participants in the All of Us Research Program. Their success is an indicator that with the proper support, FQHCs can successfully implement a complex biomedical research program in the context of their health centers.
Engaging with “Fringe” Beliefs: Why, When, and How
Authors: Schleifer McCormick Miriam 
Published: June 2023

AbstractI argue that in many cases, there are good reasons to engage with people who hold fringe beliefs such as debunked conspiracy theories. I (1) discuss reasons for engaging with fringe beliefs; (2) discuss the conditions that need to be met for engagement to be worthwhile; (3) consider the question of how to engage with such beliefs, and defend what Jeremy Fantl has called “closed-minded engagement” and (4) address worries that such closed-minded engagement involves problematic deception or manipulation. Thinking about how we engage with irrational emotions offers a way of responding to these concerns. Reflection on engagement with fringe beliefs has wider implications for two distinct philosophical discussions. First, it can help illuminate the nature of beliefs, lending support to the view that not all states which are deeply resistant to evidence thereby fail to be beliefs. Second, an implication of the view I put forth is that it need not constitute a lack of respect to adopt what Peter Strawson called “the objective stance” in relationships.
Wasserstein convergence rates in the invariance principle for deterministic dynamical systems
Authors: LIU ZHENXIN , WANG ZHE 
Published: June 2023

AbstractIn this paper, we consider the convergence rate with respect to Wasserstein distance in the invariance principle for deterministic non-uniformly hyperbolic systems. Our results apply to uniformly hyperbolic systems and large classes of non-uniformly hyperbolic systems including intermittent maps, Viana maps, unimodal maps and others. Furthermore, as a non-trivial application to the homogenization problem, we investigate the Wasserstein convergence rate of a fast–slow discrete deterministic system to a stochastic differential equation.
Forging National Belonging: Transformation, Visibility, and Dress in the German-Jewish Youth Movement Blau-Weiss, 1912–1927
Authors: Bethke Svenja 
Published: June 2023

AbstractLooking at Blau-Weiss as the first Zionist youth movement in Germany between 1912 and 1927, the article examines the role of dress in expressing new feelings of national belonging as “Jewish” in modern Germany. Drawing on publications of the movement, memoirs, and photographs, the article shows how Blau-Weiss members tried to become visible as Jews while at the same time trying to copy the dress codes of the nationalist German youth movement Wandervogel. It further shows how, after the First World War, Blau-Weiss tried to forge their own way of Zionist dressing. The article argues that it was not the actual clothes worn or the perception of others that was most crucial to the creation of a national Jewish identity, but rather the inner function that reflections and debates on dress had for Blau-Weiss members in forging and redefining their feelings of belonging and identification as Zionist Jews in Germany.
Determinants of unmet need for family planning: Evidence from the 2018 Turkey Demographic and Health Survey
Authors: Ökem Zeynep Güldem , Pekkurnaz Didem 
Published: June 2023

AbstractUnmet need for family planning is a valuable concept to indicate the discrepancy between women’s fertility preferences and contraceptive use. Unmet need may lead to unintended pregnancies and unsafe abortions. These may result in health deterioration and reduced employment opportunities for women. The 2018 Turkey Demographic and Health Survey report indicated that the estimated unmet need for family planning doubled from 2013 to 2018, returning to the high levels of the late 1990s. Considering this unfavourable change, this study aims to investigate the determinants of unmet need for family planning among married women of reproductive age in Turkey by using the 2018 Turkey Demographic and Health Survey data. Logit model estimations revealed that women who were at older ages, more educated, wealthier, and had more than one child were less likely to have unmet need for family planning. Employment statuses of women and their spouses and place of residence were significantly associated with unmet need. Results emphasised that training and counselling to enhance the use of family planning methods should effectively target young, less educated, and poor women.
Fast Filtering with Large Option Panels: Implications for Asset Pricing
Authors: Dufays Arnaud , Jacobs Kris , Liu Yuguo , Rombouts Jeroen 
Published: June 2023

AbstractThe cross section of options holds great promise for identifying return distributions and risk premia, but estimating dynamic option valuation models with latent state variables is challenging when using large option panels. We propose a particle Markov Chain Monte Carlo framework with a novel filtering approach and illustrate our method by estimating index option pricing models. Estimates of variance risk premiums, variance mean reversion, and higher moments differ from the literature. We show that these differences are due to the composition of the option sample. Restricting the option sample’s maturity dimension has the strongest impact on parameter inference and option fit in these models.
Measuring “State-Level” Economic Policy Uncertainty
Authors: Elkamhi Redouane , Jo Chanik , Salerno Marco 
Published: June 2023

AbstractWe develop 50 indices of state-level economic policy uncertainty (SEPU) based on newspaper coverage frequency using 204 million newspaper articles from Mar. 1984 to Dec. 2019. We assess the validity of our measures. Our SEPU indices vary counter-cyclically with respect to state-specific economic conditions, rise before close gubernatorial elections, and exhibit a large cross-sectional variation. We demonstrate that SEPU indices are associated with the cross-sectional variation in state-level GDP, employment, income as well as industry investment decisions. Our findings highlight the importance of economic policy uncertainty at the state level in addition to the nationwide level.
A forgotten famine of ’43? Travancore’s muffled ‘cry of distress’
Authors: Balasubramanian Aditya 
Published: June 2023

AbstractMass disease and starvation in the princely state of Travancore during the Second World War claimed some 90,000 lives. However, this episode has never received much prominence, especially when compared to the simultaneous crisis in Bengal. It is, in many ways, forgotten. Instead, Travancore’s wartime food management apparatus appears in some accounts as a success story. How did this happen? Integration into the world economy, the reordering of a rigid social structure, and popular political pressures on an autocratic princely regime created a unique set of conditions that left Travancore vulnerable to food scarcity and conflict during the Second World War. A particularly draconian princely regime that suppressed civil liberties prevented the gravity of the situation from being understood. This culminated in vastly unequal suffering and disease-related deaths. But the story is not merely one of despair. The Indian communists took advantage of war conditions to bring together agricultural and factory labourers and contribute to improving the food situation in this ‘People’s War’, while mainstream nationalists sought to obstruct the war effort and have the British ‘quit’ India. Wartime activities would shape the unique post-colonial politics of what became the state of Kerala in 1956. Intervening at the intersection of the historiographies of food and the princely states, this article adds a regional perspective to the nation-centric social history of the Second World War in South Asia. Hunger was a constitutive experience of this period across various parts of India, but the post-colonial political legacies of war could be regionally distinct.
On time or with a delay? Transposition of EU directives in the Czech Republic in relation to subsidiarity check
Authors: Hosnedlová Pavla , Pitrová Markéta 
Published: June 2023

AbstractThe government plays first fiddle in European Union (EU) decision-making processes, but a role in EU governance is also performed by the national parliament, which has gained additional competence to submit reasoned opinions based on the subsidiarity principle and participate in the political dialogue with the European Commission. The authors trace the policy-shaping and policy-taking processes and explore the impact of parliamentary and government involvement in EU policy-making on belated and timely transposition of EU directives in the Czech Republic. This comparative analysis of six directives, of which three were transposed on time and the other three from the same policy areas not, shows that the connection between ex-ante and ex-post stages still seems weak, and thus, greater involvement by parliament in EU affairs does not alone affect the time of transposition. Instead, the capacity of the government, determined partly by the salience of the legislation and its characteristics, is the main explanation for the transposition delays.
Exploring the impact of set-based concurrent engineering through multi-agent system simulation
Authors: Rismiller Sean , Cagan Jonathan , McComb Christopher 
Published: June 2023

Abstract
Set-based concurrent engineering (SBCE), a process that develops sets of many design candidates for each subproblem throughout a design project, proposes several benefits compared to point-based processes, where only one design candidate for each subproblem is chosen for further development. These benefits include reduced rework, improved design quality, and retention of knowledge to use in future projects. Previous studies that introduce SBCE in practice achieved success and had very positive future outlooks, but SBCE encounters opposition because its core procedures appear wasteful as designers must divide their time among many designs throughout the process, most of which are ultimately not used. The impacts of these procedures can be explored in detail through open-source computational tools, but currently few exist to do this. This work introduces the Point/Set-Organized Research Teams (PSORT) modeling platform to simulate and analyze a set-based design process. The approach is used to verify statements made about SBCE and investigate its effects on project quality. Such an SBCE platform enables process exploration without needing to commit many projects and resources to any given design.
Evaluating variation in pre-operative evaluation and planning for children undergoing atrial or ventricular septal defect repair
Authors: Dawson-Gore Catherine C. , Well Andrew , Wallace Scott , Teisberg Elizabeth , Born Christopher , Carberry Kathleen , Gottlieb Erin , Holt Dudley Byron , Fraser Charles D. , Mery Carlos M. 
Published: June 2023

AbstractBackground:CHD care is resource-intensive. Unwarranted variation in care may increase cost and result in poorer health outcomes. We hypothesise that process variation exists within the pre-operative evaluation and planning process for children undergoing repair of atrial septal defect or ventricular septal defect and that substantial variation occurs in a small number of care points.Methods:From interviews with staff of an integrated congenital heart centre, an initial process map was constructed. A retrospective chart review of patients with isolated surgical atrial septal defect and ventricular septal defect repair from 7/1/2018 through 11/1/2020 informed revisions of the process map. The map was assessed for points of consistency and variability.Results:Thirty-two surgical atrial septal defect/ventricular septal defect repair patients were identified. Ten (31%) were reviewed by interventional cardiology before surgical review. Of these, 6(60%) had a failed catheter-based closure and 4 (40%) were deemed inappropriate for catheter-based closure. Thirty (94%) were reviewed in case conference, all attended surgical clinic, and none were admitted prior to surgery. The process map from interviews alone identified surgery rescheduling as a point of major variability; however, chart review revealed this was not as prominent a source of variability as pre-operative interventional cardiology review.Conclusions:Significant variation in the pre-operative evaluation and planning process for surgical atrial septal defect/ventricular septal defect patients was identified. If such process variation is widespread through CHD care, it may contribute to variations in outcome and cost previously documented within CHD surgery. Future research will focus on determining whether the variation is warranted or unwarranted, associated health outcomes and cost variation attributed to these variations in care processes.
Association of dietary oxidative balance score and sleep duration with the risk of mortality: prospective study in a representative US population
Authors: Liu Jingchu , Wang Wenjie , Wen Ying 
Published: June 2023

AbstractObjective:We investigated the association between dietary oxidative balance score (DOBS) and mortality and whether this association can be modified by sleep duration.Design:We calculated DOBS to estimate the overall oxidative effects of the diet, with higher DOBS reflecting more antioxidant intake and less pro-oxidant intake. Cox proportional hazards models were employed to examine the associations between DOBS and all-cause, CVD and cancer mortality in the general population and people with different sleep durations.Setting:Prospective analysis was conducted using data from the US National Health and Nutrition Examination Survey (NHANES, 2005–2015).Participants:A total of 15 991 US adults with complete information on dietary intake, sleep duration and mortality were included.Results:During a median follow-up of 7·4 years, 1675 deaths were observed. Participants in the highest quartile of DOBS were significantly associated with the lower risk of all-cause mortality (hazard ratio (HR) = 0·75; 95 % CI 0·61, 0·93) compared with those in the lowest. Furthermore, we found statistically significant interactions between DOBS and sleep duration on all-cause mortality (P interaction = 0·021). The inverse association between DOBS and all-cause mortality was significant in short sleepers (HR = 0·66, 95 % CI 0·48, 0·92), but not in normal and long sleepers.Conclusions:Our study observed that higher DOBS was associated with lower all-cause mortality, and this association appeared to be stronger among short sleepers. This study provides nutritional guidelines for improving health outcomes in adults, especially for short sleepers.
Organic information: influential authors and organizations in the Midwestern and Northeastern United States organic and sustainable agriculture community
Authors: Abbott Anneliese 
Published: June 2023

AbstractAs organic food increases in popularity, there has been increased interest in the history of organic farming. Previous scholarship has done excellent work documenting the social and political aspects of organic and sustainable agriculture, but less research has been done on the history of organic farming methods. The purpose of this study was to address this deficiency by surveying the organic and sustainable farming community in the midwestern and northeastern United States to identify influential authors, publications and organizations. Information about influences on farming practices was created using an anonymous online survey, distributed through organic and sustainable agriculture organizations in the target region. Out of the 224 respondents who completed the survey, 171 (76%) listed books, 169 (75%) listed organizations and 123 (55%) listed influential individuals. A total of 218 authors were identified, with Eliot Coleman receiving the most mentions, followed by Rodale publications, Wendell Berry,Acres U.S.A.magazine, Masanobu Fukuoka, Joel Salatin and Michael Pollan. 242 organizations were listed, with Marbleseed (MOSES), MOFGA, NOFA, PASA, OEFFA, LSP, SFA-MN and MOFFA most frequently mentioned. These results provide a useful starting point for future research on the development and dissemination of farming methods in this region. Research priorities include conducting oral histories with still-living authors of influential books and archiving organizational records before critical historical information is lost.
Women’s Rights Close to Home? The Miami-Dade County CEDAW Ordinance as Local Practice
Authors: Zwingel Susanne 
Published: June 2023

AbstractBecause of the United States’ minimal domestic engagement with human rights, several subnational initiatives, including the Cities for CEDAW campaign, have formed to infuse human rights into local policy making. Analyzing Miami-Dade County as one locale within the Cities for CEDAW network, this article asks what happens to human rights when they are turned into urban policies. Drawing on literature theorizing the complexities of urban human rights activism and using an interpretivist framework of analysis, the article reconstructs local context features and practices promoting gender equality through the countywide CEDAW ordinance. It develops a narrative based on expert interviews and finds an unusual actor constellation in which a local officeholder led the way rather than community activists. The practices identified work within institutional constraints and highlight data collection to support informed gender policy making. The findings lead to the conclusion that both activists and scholars should think beyond the dynamics of policy formulation and more explicitly about the complexities of implementation.
Is the European Union a militant democracy? Democratic backsliding and EU disintegration
Authors: Theuns Tom 
Published: June 2023

AbstractThere has been much recent debate over whether the European Union is or should be a ‘militant democratic’ actor in order to respond to democratic backsliding in EU member states. This article argues that the EU is a militant democracy in a specific and limited sense, but that this may be normatively undesirable from a democratic perspective. I first develop a definition of militant democracy that focuses on the militant democratic paradox. I argue that the strongest justifications for militant democracy require that two conditions are met: an ‘existential threat condition’ and a ‘necessity condition’. Next, I analyse four ways in which the European Union has been said to be empowered to act in a militant democratic fashion to combat democratic backsliding in EU member states. I show how some, though not all, of these warrant the label ‘militant democracy’. Moving from the descriptive to the normative analysis, I then consider whether the necessity condition can ever be met since there is always the possibility of non-militant responses through forms of EU disintegration. If we accept this argument, EU actors should prioritize robust non-militant measures where possible while pro-democratic member states should disassociate from frankly autocratic member states where non-militant measures fail.