bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cognitive functioning in postural orthostatic tachycardia syndrome among different body positions: a prospective pilot study (POTSKog study)
Authors: Maier Andrea , Schopen Lena , Thiel Joana C. , Müller Katharina , Fimm Bruno , Schulz Jörg B. 
Published: June 2023

Abstract
Purpose
Approximately 96% of patients with postural orthostatic tachycardia syndrome (PoTS) report cognitive complaints. We investigated whether cognitive function is impaired during sitting and active standing in 30 patients with PoTS compared with 30 healthy controls (HCs) and whether it will improve with the counter manoeuvre of leg crossing.

Methods
In this prospective pilot study, patients with PoTS were compared to HCs matched for age, sex, and educational level. Baseline data included norepinephrine plasma levels, autonomic testing and baseline cognitive function in a seated position [the Montreal Cognitive Assessment, the Leistungsprüfsystem (LPS) subtests 1 and 2, and the Test of Attentional Performance (TAP)]. Cognitive functioning was examined in a randomized order in supine, upright and upright legs crossed position. The primary outcomes were the cognitive test scores between HCs and patients with PoTS at baseline testing, and among the different body positions.

Results
Patients with PoTS had impaired attention (TAP median reaction time) in the seated position and impaired executive functioning (Stroop) while standing compared with HC. Stroop was influenced by position (supine versus upright versus upright legs crossed) only in the PoTS group. Leg crossing did not result in an improvement in executive function. In patients with PoTS, there was a negative correlation of Stroop with norepinephrine plasma levels while standing.

Conclusion
Compared with HCs, PoTS participants showed impaired cognitive attention and executive function in the upright position that did not improve in the legs crossed position. Data provide further evidence for orthostatic cognitive deterioration in patients with PoTS.

Trial Registration Information
The study was registered at ClinicalTrials.gov (NCT03681080).
Theories of Growth and Propagation of Parallel Whistler-Mode Chorus Emissions: A Review
Authors: Hanzelka Miroslav , Santolík Ondřej 
Published: June 2023

AbstractThe significant role of nonlinear wave–particle interactions in the macrodynamics and microdynamics of the Earth’s outer radiation belt has long been recognised. Electron dropouts during magnetic storms, microbursts in atmospheric electron precipitation, and pulsating auroras are all associated with the rapid scattering of energetic electrons by the whistler-mode chorus, a structured electromagnetic emission known to reach amplitudes of about $$1\%$$

1
%

of the ambient magnetic field. Despite the decades of experimental and theoretical investigations of chorus and the recent progress achieved through numerical simulations, there is no definitive theory of the chorus formation mechanism, not even in the simple case of parallel (one-dimensional) propagation. Here we follow the evolution of these theories from their beginnings in the 1960s to the current state, including newly emerging self-consistent excitation models. A critical review of the unique features of each approach is provided, taking into account the most recent spacecraft observations of the fine structure of chorus. Conflicting interpretations of the role of resonant electron current and magnetic field inhomogeneity are discussed. We also discuss the interplay between nonlinear growth and microscale propagation effects and identify future theoretical and observational challenges stemming from the two-dimensional aspects of chorus propagation.
Examining the Acceptance of Blockchain by Real Estate Buyers and Sellers
Authors: Yeoh William , Lee Angela Siew Hoong , Ng Claudia , Popovic Ales , Han Yue 
Published: June 2023

AbstractBuying and selling real estate is time consuming and labor intensive, requires many intermediaries, and incurs high fees. Blockchain technology provides the real estate industry with a reliable means of tracking transactions and increases trust between the parties involved. Despite the benefits of blockchain, its adoption in the real estate industry is still in its infancy. Therefore, we investigate the factors that influence the acceptance of blockchain technology by buyers and sellers of real estate. A research model was designed based on the combined strengths of the unified theory of technology acceptance and use model and the technology readiness index model. Data were collected from 301 real estate buyers and sellers and analyzed using the partial least squares method. The study found that real estate stakeholders should focus on psychological factors rather than technological factors when adopting blockchain. This study adds to the existing body of knowledge and provides valuable insights to real estate stakeholders on how to implement blockchain technology.
One center experience with a personalized frozen-thawed embryo transfer in patients with recurrent implantation failure
Authors: Edimiris Philippos , Doehmen Cornelius , Baston-Buest Dunja Maria , Kruessel Jan-Steffen , Bielfeld Alexandra Petra 
Published: June 2023

AbstractPurposeDisplaced endometrial receptivity has been discussed as a possible cause of recurrent implantation failure in patients undergoing assisted reproductive technology. The aim of this study was to document our experience with the endometrial receptivity analysis in patients with recurrent implantation failure.MethodsThis retrospective cohort study, conducted at the Fertility Centre of the University Hospital, Duesseldorf Germany, presents the results of the endometrial receptivity analysis in 67 patients with recurrent implantation failure and compares the clinical outcome between these 67 patients who underwent a personalized frozen-thawed embryo transfer guided by the results of the endometrial receptivity analysis and 32 patients with recurrent implantation failure who performed a standardized frozen-thawed embryo transfer.ResultsThe data analysis revealed a displaced endometrial receptivity in 73% (49/67) of all tested patients. Out of these patients, 24% (12/49) were early receptive, 74% (36/49) were pre-receptive, and 2% (1/49) were post-receptive. Comparison of pregnancy rate, clinical pregnancy rate, and live-birth rate between personalized (49%, 39%, 27%, respectively) and standardized embryo transfer (44%, 31%, 19%, respectively) reveals no statistically significant difference. In both groups, patients had an average of four unsuccessful embryo transfers.ConclusionIn this cohort of patients with recurrent implantation failure, the endometrial receptivity analysis showed a high incidence of displaced endometrial receptivity. However, a personalized embryo transfer did not increase reproductive outcome. Displaced endometrial receptivity might not be the main cause for recurrent implantation failure in this cohort.
Is spontaneous echo contrast associated with device-related thrombus or embolic events after left atrial appendage occlusion? - Insights from the multicenter German LAARGE registry
Authors: Fastner Christian , Müller Claus , Brachmann Johannes , Lewalter Thorsten , Akin Ibrahim , Sievert Horst , Käunicke Matthias , Zeymer Uwe , Hochadel Matthias , Schneider Steffen , Senges Jochen , Erkapic Damir , Weiß Christian 
Published: June 2023

Abstract
Background
Interventional left atrial appendage occlusion (LAAO) provides an alternative to oral anticoagulation (OAC) for prophylaxis of thromboembolic events (TEs) in nonvalvular atrial fibrillation patients, predominantly in those with high bleeding risk and contraindications for long-term OAC. Although spontaneous echo contrast (SEC) is a well-known risk factor for atrial thrombus formation, little is known about whether this means an increased risk of device-related thrombus (DRT) or TEs following LAAO.

Methods
This substudy of the prospective, multicenter German LAARGE registry assessed two groups according to absence (SEC −) or presence of SEC (SEC +) in preprocedural cardiac imaging. Clinical and echocardiographic parameters were registered up to 1 year after LAAO.

Results
Five hundred eighty-eight patients (SEC − 85.5 vs. SEC + 14.5%) were included. More SEC + patients were implanted for OAC non-compliance (11.8 vs. 4.6%, p = 0.008) and a higher proportion received only antiplatelet therapy without OAC at hospital discharge (96.5 vs. 86.0%, p = 0.007). The SEC + patients had larger LA diameters (50 (47; 54) vs. 47 (43; 51) mm, p < 0.001), wider LAA ostia (21 (19; 23) vs. 20 (17; 22) mm at 45°, p = 0.011), and lower left ventricular ejection fraction (50 (45; 60) vs. 60 (50; 60) %, p < 0.001) on admission. Procedural success was very high in both groups (98.1%, p = 1.00). Periprocedural major adverse cardiac and cerebrovascular events and other major complications were rare in both groups (3.8 vs. 4.7%, p = 0.76). At follow-up, DRT was only detected in the SEC − group (3.8 vs. 0%, p = 1.00). The rates of TEs (SEC − 1.2 vs. SEC + 0%, p = 1.00) after hospital discharge and 1-year mortality (SEC − 12.0 vs. SEC + 11.8%, p = 0.96) were not significantly different between the two groups.

Conclusions
Presence of SEC at baseline was not associated with an increased rate of DRT or TEs at 1-year follow-up after LAAO in LAARGE.
Navier–Stokes–Fourier system with phase transitions
Authors: Watson Stephen J. 
Published: June 2023

AbstractWe consider the Navier–Stokes–Fourier ($$\mathcal NSF$$NSF) system for a class of compressible fluids that exhibit agas-liquidphase transition at low temperatures. For the initial-boundary value problem corresponding to thermally insulated end-points that are held at a constant pressure, we establish the existence and uniqueness of temporally global classical solutions. A novel feature of the analysis presented here is the derivation ofuniformpoint-wise apriori estimates on the specific volume, which refines the non-uniform estimates framework developed in Watson (Arch Ration Mech Anal 153:1–37, 2000).
Investigating the role of preference variation in the perceptions of railway passengers in Great Britain
Authors: Monsuur Fredrik , Enoch Marcus , Quddus Mohammed , Meek Stuart 
Published: June 2023

AbstractThis study explores the factors associated with passenger satisfaction on the UK railways. To uncover taste variation, the data was segmented into three homogeneous groups of passengers through a latent class ordered logit model, whereby the class allocation was based on observed personal and trip characteristics. The findings suggest that there is significant variation in the impact of service attributes on overall satisfaction across the segments, ‘class a’, ‘class b’ and ‘class c’. Class a (15% of the sample) consists of moderately dissatisfied to highly dissatisfied passengers, for whom ‘punctuality/reliability’ is most impactful on overall satisfaction. Respondents in this class are much more likely to experience adverse service conditions such as delays or crowding conditions. Class b (32% of the sample) consists of passenger who are quite critical and moderately satisfied, for whom ‘hedonic’ factors such as ‘upkeep and repair of the train’ and ‘seat comfort’ were most impactful. Finally, class c (53% of the sample) consists of passengers that are generally satisfied, and for whom the ‘value for money of the ticket price’ is most impactful on overall satisfaction. Interestingly, for both ‘class b’ and ‘class c’, ‘punctuality/reliability’ plays a more limited role in determining overall satisfaction compared to ‘class a’. This suggests that the role of ‘punctuality/reliability’ in determining overall satisfaction is more complex than presented in the literature thus far. Finally, unobserved taste variation plays an important role in the model, as the class allocation is not always easily linked to observed groups in the data. This paper thus highlights the importance of accounting for unobserved and systematic sources of heterogeneity in the data and could provide useful insights for analysts, policy makers and practitioners, to provide more targeted strategies to improve passenger satisfaction.
Positive antiphospholipid antibodies: observation or treatment?
Authors: Grygiel-Górniak Bogna , Mazurkiewicz Łukasz 
Published: June 2023

AbstractAntiphospholipid antibodies (APLAs) are primarily directed toward phospholipid-binding proteins and are responsible for thrombotic events. APLAs include anti-β2Glycoprotein I (anti-β2GPI), anticardiolipin (anti-CL) antibodies, and lupus anticoagulant. These antibodies are typical markers of antiphospholipid syndrome (APS) and are a part of its diagnostic criteria. Many data underline the presence of APLAs in other rheumatic diseases (e.g., systemic lupus erythematosus, systemic sclerosis, Sjögren’s syndrome, rheumatoid arthritis and Behçet’s disease). However, they are also detected in patients with cancer, infection, and neurological disorders. Furthermore, healthy individuals may be carriers of APLAs. Chronic asymptomatic APLAs presence is most common in the elderly and subjects with chronic diseases (including malignancies). Specific kinds of APLAs are considered markers of oncological progression. These antibodies occur in 6% of pregnant women (without diagnosed APS) and are related to many pregnancy complications. Of worth, various types of APLAs are reported to have different prothrombotic properties. The risk of thrombotic events in APLA-positive but clinically naïve patients raises many questions in clinical practice. This manuscript analyses various clinical situations and consequences of the APLAs’ presence, particularly in patients without diagnosed APS. The prevalence, etiology, molecular background, and prothrombotic properties of numerous APLAs are broadly discussed. The new management approach in different clinical conditions and organ complications is present in the context of recent recommendations. Discussed data underlines that adequate and timely introduced thromboprophylaxis can decrease the risk of thrombus formation and prevent increased morbidity.
Microscale Modelling of Flow, Heat and Mass Transport During Vacuum Cooling of Porous Foods: Effective Property Computation
Authors: Ajani Clement Kehinde , Zhu Zhiwei , Sun Da-Wen 
Published: June 2023

AbstractA microscale modelling framework to compute effective properties related to flow, heat and mass transfer during vacuum cooling (VC) of porous foods was developed. A heterogeneous computational domain reconstructed from steamed bread (SB) was used for modelling, while the cellular water transport in SB investigated using nuclear magnetic resonance was applied for model validation. The computed porosity (63.47 ± 1.05%), effective permeability (1.91 ± 0.39 × 10−11 m2), effective thermal conductivity, (0.33 ± 0.08 W m−1 K−1), and effective diffusivity (5.56 ×  ± 0.24 10−8 m2 s−1) were in the same range as those measured from the experiment/literature. Also, the analysis revealed that microstructural variability significantly affected the estimated effective properties. The microscale model yielded results similar to the lumped formulation but provided details not visible in the latter. Therefore, the developed model provides a framework for multiscale modelling, which could lead to a better understanding of the underlying moisture loss mechanisms during VC.
A Family of Approaches for Full 3D Reconstruction of Objects with Complex Surface Reflectance
Authors: Addari Gianmarco , Guillemaut Jean-Yves 
Published: June 2023

Abstract3D reconstruction of general scenes remains an open challenge with current techniques often reliant on assumptions on the scene’s surface reflectance, which restrict the range of objects that can be modelled. Helmholtz Stereopsis offers an appealing framework to make the modelling process agnostic to surface reflectance. However, previous formulations have been almost exclusively limited to 2.5D modelling. To address this gap, this paper introduces a family of reconstruction approaches that exploit Helmholtz reciprocity to produce complete 3D models of objects with arbitrary unknown reflectance. This includes an approach based on the fusion of (orthographic or perspective) view-dependent reconstructions, a volumetric approach optimising surface location within a voxel grid, and a mesh-based formulation optimising vertices positions of a given mesh topology. The contributed approaches are evaluated on synthetic and real datasets, including novel full 3D datasets publicly released with this paper, with experimental comparison against a wide range of competing methods. Results demonstrate the benefits of the different approaches and their abilities to achieve high quality full 3D reconstructions of complex objects.
Blur Invariants for Image Recognition
Authors: Flusser Jan , Lébl Matěj , Šroubek Filip , Pedone Matteo , Kostková Jitka 
Published: June 2023

AbstractBlur is an image degradation that makes object recognition challenging. Restoration approaches solve this problem via image deblurring, deep learning methods rely on the augmentation of training sets. Invariants with respect to blur offer an alternative way of describing and recognising blurred images without any deblurring and data augmentation. In this paper, we present an original theory of blur invariants. Unlike all previous attempts, the new theory requires no prior knowledge of the blur type. The invariants are constructed in the Fourier domain by means of orthogonal projection operators and moment expansion is used for efficient and stable computation. Applying a general substitution rule, combined invariants to blur and spatial transformations are easy to construct and use. Experimental comparison to Convolutional Neural Networks shows the advantages of the proposed theory.
Portus, New Contributions to its Research: Construction Systems and Dating of the East–West Docks
Authors: Meléndez Javier Bermejo , Campos Juan M. , Meléndez Alberto Bermejo , Sutilo Lucía Fernández , Sebastiani Renato , Sánchez Hernando L. J. 
Published: June 2023

AbstractThe archaeological site of Portus (Ostia Antica), is a most important ports of the ancient world. Since 2017, the University of Huelva, in collaboration with the Archaeological Park of Ostia Antica, has been developing a research project on one of its interior piers, the so-called lantern. Said east–west structure or pier is the best example of its category in the port complex. With a length of about 150 m. the latest research has provided numerous and interesting data on its architecture and diachrony, highlighting significant phases in its evolution from its construction to its final abandonment in the beginnings of the Middle Ages. Therefore, the results presented here represent a significant novelty in the general knowledge of Portus and in that of its docks in particular.
Factors associated with weight gain in pre- and post-menopausal women receiving adjuvant endocrine therapy for breast cancer
Authors: Uhelski Anna-Carson Rimer , Blackford Amanda L. , Sheng Jennifer Y. , Snyder Claire , Lehman Jennifer , Visvanathan Kala , Lim David , Stearns Vered , Smith Karen Lisa 
Published: June 2023

Abstract
Purpose
Weight gain after breast cancer poses health risks. We aimed to identify factors associated with weight gain during adjuvant endocrine therapy (AET).

Methods
Women initiating AET enrolled in a prospective cohort. Participants completed FACT-ES plus PROMIS pain interference, depression, anxiety, fatigue, sleep disturbance and physical function measures at baseline, 3, 6, 12, 24, 36, 48 and 60 months. Treatment-emergent symptoms were defined as changes in scores in the direction indicative of worsening symptoms that exceeded the minimal important difference at 3 and/or 6 months compared to baseline. We used logistic regression to evaluate associations of clinicodemographic features and treatment-emergent symptoms with clinically significant weight gain over 60 months (defined as ≥ 5% compared to baseline) in pre- and post-menopausal participants.

Results
Of 309 participants, 99 (32%) were pre-menopausal. The 60 months cumulative incidence of clinically significant weight gain was greater in pre- than post-menopausal participants (67% vs 43%, p < 0.001). Among pre-menopausal participants, treatment-emergent pain interference (OR 2.49), aromatase inhibitor receipt (OR 2.8), mastectomy, (OR 2.06) and White race (OR 7.13) were associated with weight gain. Among post-menopausal participants, treatment-emergent endocrine symptoms (OR 2.86), higher stage (OR 2.25) and White race (OR 2.29) were associated with weight gain while treatment-emergent physical function decline (OR 0.30) was associated with lower likelihood of weight gain.

Conclusions
Weight gain during AET is common, especially for pre-menopausal women. Clinicodemographic features and early treatment-emergent symptoms may identify at risk individuals.

Implications for cancer survivors
Patients at risk for weight gain can be identified early during AET.

Clinical trials.gov identifier
NCT01937052, registered September 3, 2013.
Additive manufacturing of flexible 3D surface electrodes for electrostatic adhesion control and smart robotic gripping
Authors: Kim Dong Geun , Je Hyeongmin , Hart A. John , Kim Sanha 
Published: June 2023

AbstractMechanically flexible surface structures with embedded conductive electrodes are attractive in contact-based devices, such as those used in reversible dry/adhesion and tactile sensing. Geometrical shapes of the surface structures strongly determine the contact behavior and therefore the resulting adhesion and sensing functionalities; however, available features are often restricted by fabrication techniques. Here, we additively manufacture elastomeric structure arrays with diverse angles, shapes, and sizes; this is followed by integration of conductive nanowire electrodes. The fabricated flexible three-dimensional (3D) surface electrodes are mechanically compliant and electrically conductive, providing multifunctional ability to sense touch and to switch adhesion via a combined effect of shear- and electro adhesives. We designed soft, anisotropic flexible structures to mimic the gecko’s reversible adhesion, which is governed by van der Waals forces; we integrated nanowires to further manipulate the localized electric field among the adjacent flexible 3D surface electrodes to provide additional means to digitally tune the electrostatic attraction at the contact interface. In addition, the composite surface can sense the contact force via capacitive sensing. Using our flexible 3D surface electrodes, we demonstrate a complete soft gripper that can grasp diverse convex objects, including metal, ceramic, and plastic products, as well as fresh fruits, and that exhibits 72% greater electroadhesive gripping force when voltage is applied.