bluuebunny/crossref_metadata_2025_split huggingface dataset:
Maresin-2 promotes mucosal repair and has therapeutic potential when encapsulated in thermostable nanoparticles
Authors: Miranda Jael , Brazil Jennifer C. , Morris Aaron H. , Parkos Charles A. , Quiros Miguel , Nusrat Asma 
Published: January 2023

Resolution of inflammation and mucosal wound healing are crucial processes required to re-establish homeostasis following injury of mucosal tissues. Maresin-2 (MaR2), a lipid specialized pro-resolving mediator derived from omega-3 polyunsaturated fatty acid, has been reported to promote resolution of inflammation. However, a potential role for MaR2 in regulating mucosal repair remains undefined. Using lipidomic analyses, we demonstrate biosynthesis of MaR2 in healing intestinal mucosal wounds in vivo. Importantly, administration of exogenous MaR2 promoted mucosal repair following dextran sulfate sodium-induced colitis or biopsy-induced colonic mucosal injury. Functional analyses revealed that MaR2 promotes mucosal wound repair by driving intestinal epithelial migration through activation of focal cell-matrix adhesion signaling in primary human intestinal epithelial cells. Because of its labile nature, MaR2 is easily degradable and requires ultracold storage to maintain functionality. Thus, we created thermostable polylactic acid MaR2 nanoparticles that retain biological activity following extended storage at 4 °C or above. Taken together, these results establish MaR2 as a potent pro-repair lipid mediator with broad therapeutic potential for use in promoting mucosal repair in inflammatory diseases.
Dialogic interaction between player and non-player characters in animal crossing
Authors: Lazzeretti Cecilia , Gatti Maria Cristina 
Published: January 2023

Abstract
Dialogic interaction is a distinctive feature of Animal Crossing, a social simulation video game developed by
Nintendo, yet, little attention has been paid to it from a discourse analytical perspective. This paper aims to explore how AC
characters are characterised through language and which discourse strategies are applied to engage players. The analysis, based on
a corpus of dialogues transcribed by fans of the game, relies on corpus-linguistics methodologies and can be framed within the
context of ludolinguistics. The study shows that emotive language is used to create an active interaction between player and non-player characters (NPCs).
Even though NPCs are minimally characterized in terms of gender, age, or social status, the collocational analysis of “I” and
“you” highlights two opposite personalities interacting in the dialogues: type A, lexically represented as extroverted, dynamic,
and active, and type B, represented as kind, hesitant, and passive.
Potential emerging constraints and management strategies of different honeybee species in Pakistan: A review
Authors: Usman Muhammad , Hasnain Muhammad , Banaras Saira , Akram Muhammad , Abbas Qaisar , Shah Jawad Ali , Tabasum Saba , Shah Sajid Ali , Raza Ali , Khan Muhammad Nadeem , Jamil Muhammad 
Published: January 2023

Abstract

The honey bee (
Hymenoptera Apidae
) is a valuable insect that can be found all around the globe, except in polar regions. Apis mellifera contributes over dollar 200 billion to the world’s economy annually. In Pakistan, pollination-dependent crops have a productivity worth of 1590 million US$, with 61 main crops relying on the pollination of honey bees. Loss of honeybees to a certain level may lead to starvation. In a developing country like Pakistan, it is an issue with food security. Many biotic and abiotic factors are challenging in brooding and rearing honeybees in the country. Excessive use of pesticides, lack of skilled personnel and deforestation is leading to a decline in the population of honeybees. While the need for honeybee products is tremendously increasing with every passing day. The country’s unique vegetative diversity has a significant ecological and economic impact on local wildlife conservation. If properly developed, it offers enormous potential for a long-term beekeeping enterprise. Beekeeping is primarily practiced in Khyber Pakhtunkhwa and the central and northern areas of the Punjab provinces of Pakistan. Pakistani honey is well-known throughout the Middle East for its distinct flavor and high quality. Every year, Pakistan sells roughly 4000 tons of honey to Arab countries, costing about $ 23 million. This review study briefly describes different honeybee species’ potential constraints and management in Pakistan and will be helpful in developing a sense of awareness that conserving honeybees is a matter of food security.
Thermal management and packaging of wide and ultra-wide bandgap power devices: a review and perspective
Authors: Qin Yuan , Albano Benjamin , Spencer Joseph , Lundh James Spencer , Wang Boyan , Buttay Cyril , Tadjer Marko , DiMarino Christina , Zhang Yuhao 
Published: January 2023

Abstract
Power semiconductor devices are fundamental drivers for advances in power electronics, the technology for electric energy conversion. Power devices based on wide-bandgap (WBG) and ultra-wide bandgap (UWBG) semiconductors allow for a smaller chip size, lower loss and higher frequency compared with their silicon (Si) counterparts, thus enabling a higher system efficiency and smaller form factor. Amongst the challenges for the development and deployment of WBG and UWBG devices is the efficient dissipation of heat, an unavoidable by-product of the higher power density. To mitigate the performance limitations and reliability issues caused by self-heating, thermal management is required at both device and package levels. Packaging in particular is a crucial milestone for the development of any power device technology; WBG and UWBG devices have both reached this milestone recently. This paper provides a timely review of the thermal management of WBG and UWBG power devices with an emphasis on packaged devices. Additionally, emerging UWBG devices hold good promise for high-temperature applications due to their low intrinsic carrier density and increased dopant ionization at elevated temperatures. The fulfillment of this promise in system applications, in conjunction with overcoming the thermal limitations of some UWBG materials, requires new thermal management and packaging technologies. To this end, we provide perspectives on the relevant challenges, potential solutions and research opportunities, highlighting the pressing needs for device–package electrothermal co-design and high-temperature packages that can withstand the high electric fields expected in UWBG devices.
The present and future status of heavy neutral leptons
Authors: Abdullahi Asli M , Barham Alzás Pablo , Batell Brian , Beacham James , Boyarsky Alexey , Carbajal Saneli , Chatterjee Animesh , Crespo-Anadón José I , Deppisch Frank F , De Roeck Albert , Drewes Marco , Martin Gago Alberto , Gonzalez Suarez Rebeca , Goudzovski Evgueni , Hatzikoutelis Athanasios , Hernandez-Garcia Josu , Hostert Matheus , Hufnagel Marco , Ilten Philip , Izmaylov Alexander , Kelly Kevin J , Klarić Juraj , Kopp Joachim , Kulkarni Suchita , Lamoureux Mathieu , Lanfranchi Gaia , López-Pavón Jacobo , Mikulenko Oleksii , Mooney Michael , Nemevšek Miha , Ovchynnikov Maksym , Pascoli Silvia , Plestid Ryan , Rashad Darwish Mohamed , Leo Redi Federico , Ruchayskiy Oleg , Ruiz Richard , Shaposhnikov Mikhail , Shchutska Lesya , Shoemaker Ian M , Shrock Robert , Sousa Alex , Van Remortel Nick , Syvolap Vsevolod , Takhistov Volodymyr , Tastet Jean-Loup , Timiryasov Inar , Vincent Aaron C , Yu Jaehoon 
Published: January 2023

Abstract
The existence of nonzero neutrino masses points to the likely existence of multiple Standard Model neutral fermions. When such states are heavy enough that they cannot be produced in oscillations, they are referred to as heavy neutral leptons (HNLs). In this white paper, we discuss the present experimental status of HNLs including colliders, beta decay, accelerators, as well as astrophysical and cosmological impacts. We discuss the importance of continuing to search for HNLs, and its potential impact on our understanding of key fundamental questions, and additionally we outline the future prospects for next-generation future experiments or upcoming accelerator run scenarios.
Cross section measurements for 9Be(d, t)8Be reaction at the low-energy region (E < 100 keV)
Authors: Dai Xiao Rong , Wang Yun Yu , Li Duo , Zhao Wei Jia , Han Ya Fei , Han Xue Yan , Fang Kai Hong 
Published: January 2023

Abstract
To obtain the cross sections of the 9Be(d, t)8Be reaction, a thick beryllium target was bombarded with a deuteron beam from 78 to 100 keV, with an energy step of 2 keV. The charged particles emitted from the d-9Be interaction were accumulated, and the cross sections were deduced from the thick-target yields of emitted tritium. The present work, in conjunction with the data reported in the high-energy region, extended the directly measured values of cross section to 65 keV in the center-of-mass system, thereby filling in the nuclear data gap in the low-energy region.
First observations of confined fast ions in MAST Upgrade with an upgraded neutron camera
Authors: Cecconello M , Dolby I J , Sperduti A , Rivero-Rodriguez J , Ericsson G , Fitzgerald I , Allan S Y , Voller J , Honey B , Nizar B A , Elmore S D 
Published: January 2023

Abstract
Spherical tokamaks are key to the successful design of operating scenarios of future fusion reactors in the areas of divertor physics, neutral beam current drive and fast ion physics. MAST Upgrade, which has successfully concluded its first experimental campaign, was specifically designed to address the role of the radial gradient of the fast ion distribution in driving the excitation of magneto-hydrodynamic (MHD) instabilities, such as toroidal Alfvén eigenmodes, fish-bones and long-lived mode, thanks to its two tangential neutral beam injection systems, one on the equatorial plane and one that is vertically shifted 65 cm above the equatorial plane. To study the fast ion dynamics in the presence of such instabilities, as well as of sawteeth and neo-classical tearing modes, several fast ion diagnostics were upgraded and new ones added. Among them, the MAST prototype neutron camera (NC) has been upgraded to six, equatorial sight-lines. The first observations of the confined fast ion behavior with the upgraded NC in a wide range of plasma scenarios characterized by on-axis and/or off-axis heating and different MHD instabilities are presented here. The observations presented in this study confirm previous results on MAST but with a higher level of detail and highlight new physics observations unique to the MAST Upgrade. The results presented here confirm the improved performance of the NC Upgrade, which thus becomes one of the key elements, in combination with the rich set of fast ion diagnostics available on the MAST Upgrade, for a more constrained modeling of the fast ion dynamics in fusion reactor relevant scenarios.
Damage identification of thin plate-like structures combining improved singular spectrum analysis and multiscale cross-sample entropy (ISSA-MCSEn)
Authors: Wang Jiacheng , Lu Guangtao , Song Huijun , Wang Tao , Yang Dan 
Published: January 2023

Abstract
In this paper, a new method integrating the improved singular spectrum analysis and the multiscale cross-sample entropy Improved Singular Spectrum Analysis and Multiscale Cross-Sample Entropy, (ISSA-MCSEn) is developed to identify the size of early damages in thin plate-like structures. In the algorithm, with the help of improved singular spectrum analysis (ISSA), the principal components relevant to the reference and damage-induced signals are successfully extracted, and then the components related to the damage are reconstructed for damage size detection. Lastly, the multiscale cross-sample entropy (MCSEn) of the reconstructed signal is computed as a new damage index to evaluate the size of the damage. To validate the proposed ISSA-MCSEn algorithm, two different experiments are conducted on aluminum and composite fiber reinforced polymer (CFRP) plates to detect simulated crack and through-hole, respectively. Comparative performance analysis of ISSA and singular spectrum analysis (SSA) demonstrates that the total increment of the normalized MCSEn by using ISSA is 30%–81% while the one by using SSA is only 6.5%–9%, which demonstrates that the performance of the proposed ISSA is much better than SSA. The experimental results also show that the average of the normalized MCSEn of the proposed algorithm increases by over 77% and 28% as the size of the two damages in CFRP and aluminum plates changes from 0 to 8 mm and 0 to 1.2 mm, respectively. Moreover, the relationship between the normalized MCSEn and damages’ size is well linear, and the Pearson’s coefficient of their fitting curves is more than 0.99, which demonstrates that this linear relationship can be employed for damage size detection in both CRFP and aluminum plates. The linear relationship between the damage size and normalized MCSEn is used for damage detection, and the relative error between the actual and detected size is 1.64%–6.92%. In addition, the performance comparison of ISSA-MCSEn and SSA-FuzzyEn shows that the total increment of the ISSA-MCSEn algorithm due to the damage is 30%–81% while the one of SSA-FuzzyEn is only 4%–15%, which indicates that the proposed ISSA-MCSEn is more sensitive to the damage than SSA-FuzzyEn and it is more suitable for detection of small-size damages.
Accelerated long-term aging study of new antioxidant plastic scintillators
Authors: Song H. , Li X. , Yu B. , Yang C. , Ling X. , Zhu Z. , Hu T. , Zhao T. , Jin B. , Zhang H. 
Published: January 2023

Abstract
In this paper, the smaller plastic scintillator (polystyrene as solvent) tiles are polymerized and shaped by two methods, i.e. injection molding technology and thermal pressing technology by domestic manufacturer, to be operated for more than 10 years in the hadron calorimeter of the Circular Electron Position Collider (CEPC) or other purposes. Other benefits include, researching aging problems, by adding 0.1% material antioxidants of 2,6-Di-tert-butyl-4-methylphenol (BHT) and without BHT, and according to Van't Hoff rule of equivalent chemical reaction rate of high temperature, the 10 years aging study is simulated in short term. A strobed coincidence setup is arranged to test the light yield of the tile to be measured with silicon photomultipliers (SiPMs) with ADC read out and a simple trigger system with small solid angle acceptance is adopted. The light yields of measured tiles without BHT decrease by about 26.6% (injection molding technology) and 43.3% (thermal polymerization technology) after ten-year equivalent aging time. Meanwhile, the light yields of the tiles with BHT almost did not change after ten-year equivalent aging time.
Investigation of Ground Deformation around The Segments of Kendeng Fault in East Java 2017-2020 using Multi-Temporal InSAR Analysis with GACOS Correction Product
Authors: Syahputri B E A , Anjasmara I M , Hayati N 
Published: January 2023

Abstract
Multi-Temporal Interferometric SAR (MT-InSAR) analysis technique can provide spatially continuous measurements of the ground deformation and monitoring caused by the movement of four segments in the Kendeng Fault, East Java. Most ground deformation in these segments is indicated by the dominance of local thrust movements, folds, and the seismic density of earthquakes. In this study, ground deformation detection was carried out using the Small Baseline Subset Algorithm in the MT-InSAR process with the tropospheric correction from GACOS to determine ground deformation during 2017-2020. The percentage of change in the deformation velocity value resulting from applying the GACOS correction is up to 33.8% compared to without the tropospheric correction. The most significant troposphere effect correction is the area around the Cepu segments, which are dominated by high elevation thrust and folds. The results of the mean LOS velocity around the southern segments of Cepu, Waru, and Surabaya based on the Sentinel 1A SAR represent the occurrence of land subsidence in the south part of the area around segments with values ranging from 3.0 mm/yr to 6.0 mm/yr. Thus, the deformation effect causes land subsidence in the area around the delineation of the northern fault segment up to -3.0 mm/yr.
Physiographic Study for Hydrology of Benowo Region Surabaya
Authors: Indriani Rista Fitri , Utama Widya 
Published: January 2023

Abstract
This study seeks to identify the physiographic characteristics based on slope and land use that influence water management in the Benowo area of Surabaya. This research utilized DEM data and Landsat 8 data. Slope analysis and land use analysis were employed in the data processing procedure. The slope classification map yielded five categories: flat, sloping, slightly steep, steep, and very steep. The land classification map featured five categories: agriculture, settlements, industrial, plantations, and waters. Based on the slope and land use, a flow coefficient analysis was performed. The average flow coefficient for the Benowo area of Surabaya was 0.35, which was categorized as a medium flow coefficient, and 65 percent of the water was absorbed by the soil below the surface. Changes in land function in the Benowo region, from agriculture and water to residential or industrial, will have a significant impact on the flow coefficient value. Changes in land function result in increased surface runoff. Water management is a crucial aspect of development planning. This study’s findings provide a foundation for hydrological engineering, development, improvement, utilization, and control of water flow, particularly in the Benowo area of Surabaya.
Integration of Market Price Comparison Approach and Income Capitalization Approach in Urban Land Valuation
Authors: Sugito Nanin Trianawati , Gumilar Irwan , Hendriatiningsih Sadikin , Leksono Bambang Edhi 
Published: January 2023

Abstract
Land is one of the economic goods. The high demand for land while the land supply is fixed, causes the increase in land prices to be out of control. Land is closely related to the cadastral system. The cadastral system is the driving force behind the operation of a land administration system that integrates the functions of land tenure, land value, land use, and land development. A complete cadastre has a component in the form of a cadastral map that is connected to juridical data records, including land values and their designations. Land value is the product of land valuation. Land valuation consists of several approaches, namely market price comparison approach, cost approach, and income capitalization approach. Estimating urban land values requires rapid and accurate land valuations. This research integrates the market price comparison approach and the income capitalization approach. Geostatistical analysis is applied in land value modeling. The resulting mathematical model of land value is expected to reflect the actual value
Alternative Route Planning Analysis of Tourism Transport Using Analytical Hierarchy Process (AHP) and Network Analysis Methods (Case Study: Jember Regency)
Authors: Bachtiar A S A , nurwatik  
Published: January 2023

Abstract
Tourism is one of the sectors that continue to be developed according to the Spatial Planning Regulation (RTRW) of Jember Regency in 2015 – 2035. In September 2021, The Regent of Jember announced officially the Jember Regency Tourism Transport to maximize the potential of educational tourism. Therefore, it is required to provide a sufficient information with respect to the accessibility of tourist attraction. This paper purposes to integrate Analytical Hierarchy Process (AHP) and GIS network analysis to generate a ranking of the potential of educational tourism objects based on the parameters of accessibility, amenities, and attractions according to Minister of Tourism Regulation Number 5 of 2017 and produce alternative routes between tourism objects based on travel time, tour time, and tourism object situation scenarios. The results indicate the weight of the accessibility criteria is 0.60, the amenities criteria is 0.27 and the attraction criteria is 0.13. From the processing of these parameters, educational tourism with the high potential category is Agrotourism Research Center for Coffee and Cocoa Jember, Sukorambi Botanical Garden, and Jember Mini Zoo, and the category of educational tourism with low potential include Tanoker, Tobacco Museum, and Duplang Site. In addition, the network analyst result generates 3 routes. The first route is Jami, Al- Baitul Amien Mosque – Tobacco Museum Jember – Agrotourism Research Center for Coffee and Cocoa Jember - Jami, Al-Baitul Amien Mosque with 41.5-kilometer distance, the total duration of travel time and the assumption of tour time is 7 hours 7 minute. The second route is Jami, Al-Baitul Amien Mosque – Duplang Site – Jember Mini Zoo - Jami, Al-Baitul Amien Mosque with the total travel time duration and tour time assumption is 7 hours 41 minutes and 39-kilometer travel distance. While the third route is Jami, Al-Baitul Amien Mosque – Tanoker – Sukorambi Botanical Garden - Jami, Al- Baitul Amien Mosque with the total duration of travel time and tour time assumption is 7 hours 40 minutes with 59.9-kilometer distance.
Production of quality early-generation seed potatoes in Bali, Indonesia
Authors: Astarini I A , Margareth D , Febryanti N P K , Defiani M R , Temaja I G R M 
Published: January 2023

AbstractPotato is an essential crop in Bali. The potato productivity in Bali is still low compared to other provinces in Indonesia. The main problem is difficulties in obtaining quality seeds at affordable prices. This study aimed to ensure the survival of tissue culture seedlings during acclimatization and produce good quality early-generation seed potatoes. The research was conducted at Batusesa Village, Tabanan, Bali, from March - July 2021. There were two experiments, the first was the production of G0 seed potato, and the second was the production of G1 seed. Production of G0 was done using Factorial Randomized Block Design with two factors, variety (Granola and Vega) and media (charred rice husk, charred rice husk + coco peat, charred rice husk + coco peat + soil). Each treatment combination consisted of 100 cuttings. Variables observed were harvest time, tuber weight, and total tubers per plant. The result shows that Vega has a shorter harvesting time (65 days) compared to Granola (70 days). Vega produced heavier tuber in all media trials. Granola made more tubers in M3 media. Experiment on G1 production was done using Randomized Block Design with two factors, variety (Granola and Vega) and G0 seed tuber size (<15 gram and ≥ 15 gram; <50 gram and ≥ 50 gram). Vega produced more tubers than Granola; while Granola produced bigger tubers than Vega. Bigger seed tubers had the highest tuber production and bigger size tubers in both varieties.