bluuebunny/crossref_metadata_2025_split huggingface dataset:
Serum CRP and smear grading standards between patients with lung TB
Authors: Verma Anita , Sogat Rajendra 
Published: April 2023

Assessing C-reactive protein concentration in lung TB as a predictor of sputum conversion and identifying the link active Serum-C protein and severity of disease. Newly diagnosed lung tuberculosis patients and age group & gender compared to healthy people in the control group. A high-dose experimental test of active C-ELISA protein was used to measure Serum-C-reactive protein. ANOVA and t tests have been used to determine mathematical significance. In patients with AFB positive, Serum-C-reactive protein levels were significantly higher in AFB3 + patients (63.12 ± 11.21) compared with AFB2 + patients (36.25 ± 7.42), AFB1 + (14.26 ± 3.12) and and AFB ± 7.23 (7.23 patients) 7.23) 2.19). Serum-C-reactive protein level should better understand the severity of the disease which plays a key role in diagnosing and determining the clinical outcome of the disease.
Clinico-microbiological profile of healthcare associated infections in a neonatal intensive care unit and its relation with environmental surveillance
Authors: Moses Serra Saji , Kuruvilla Thomas S , B K Praveen 
Published: April 2023

Healthcare associated infections (HAI’s) or nosocomial infections are frequently encountered in neonatal intensive care units (NICU’s), resulting in morbidity as well as mortality of new born babies, with varying predisposing factors and microbiological profile. This study was conducted to identify the most common HAI among the neonates admitted in the NICU, to identify the risk factors of HAI’s in neonates and to compare the bacteriological profile of culture positive cases with the results of environmental survey. This was a prospective study, conducted for a duration of one and a half years from December 2018 to May 2020. Environmental samples from the NICU as well as clinical samples from neonates admitted to the NICU of a tertiary care centre for a duration of more than 2 calendar days were collected. The most common HAI in the NICU was VAP (41.6%), followed by CLABSI (21.8%). Statistically significant risk factors for neonatal nosocomial infection were preterm birth, LSCS, presence of comorbidities, Low Birth Weight, absence of breast feeding and Apgar score. The most common Gram negative organism isolated was Acinetobacter baumannii (18.8%) and Gram positive organism as Methicillin Resistant Coagulase negative Staphylococcus (MRCoNS) (13.9%).Acinetobacter baumanni above average isolation rate was matching with the growth of the similar organism each month, according to the surveillance report. The most common HAI among neonates in our study was VAP, majority of which were caused by Gram negative bacteria. Acinetobacter baumanni was found to have an isolation rate above average on environmental surveillance, indicating its role in causing HAI’s in neonates admitted to the NICU. However, this study did not show a definitive association between HAI and the environmental surveillance report.
An insight into gender based variations of autonomic functions among young adults
Authors: Patra Subhadeep , Chatterjee Sudakshina , De Kaberi , Chanda Debarati , Panda Prem Sagar 
Published: April 2023

Since this is a vital developmental phase, studying the health patterns of young adults, particularly cardiovascular health, is critical. Autonomic function testing (AFT) is a crucial non-invasive procedure for determining the state of one's cardiovascular system. There are only a few studies on autonomic responsiveness in young people. To study the autonomic responses to various cardiovascular autonomic function tests among young adult subjects and to look into the gender-based variations.Males made up 114 (50.67 percent) of the total 225 individuals, while females made up the rest. The study's target age group was 18-29 years old. The CANWIN analyser of genesis medical systems was used to investigate autonomic function tests such as resting heart rate, heart rate reaction to slow deep breathing (SDB), Valsalva Ratio (VR), 30:15 ratios response to standing, and blood pressure response to sustained handgrip. CANWIN is a state-of-the-art Cardiac Autonomic Neuropathy (CAN) Analysis System with interpretation for PC Windows*. The data was analysed statistically using STATA software (version 13.1).: Dysautonomia was seen in 150 of the 225 participants (66.66 percent). The number of dysautonomia participants was not statistically different between males and females (P value=0.15).: Anxiety, stress, a poor diet, and a disrupted sleep cycle could all contribute to the high number of dysautonomia patients. There have been a number of reports linking dysautonomia to nutritional deficits. To investigate the causative factors, more longitudinal studies including nutritional status assessments are needed.
Study of prevalence of anaemia and haematological parameters in children below 12 years in Northern Karnataka
Authors: VG Mujumdar , Chengty Siddaling , Rajkumar Papanka , Siddiqua Ayesha 
Published: April 2023

Anaemia may be defined as a reduction in red blood cell (RBC) mass or blood haemoglobin (HGB) concentration. The most common cause of anaemia in newborns include blood loss, Rh or ABO incompatibility in 3 to 6 months suggests hemoglobinopathy, Nutritional iron deficiency causes after six months hence symptoms of blood examination in children play a significant role below 12 years. 92 children below 12 years of age having anaemia were studied. The blood examination was done to rule out PCV, MCV, MCH, MCHC, RPW, Hb%, PS study, reticulocyte count, and serum iron (Fe), Serum B, folic acids. The types of anaemia were 53(57.6%) anaemia, 13(14.1%) Thalassemia, 10(10.8%) Megablastic anaemia, 8(8.6%) Anaemia of acute haemorrhage, 5(5.4%) sickle cell anaemia, 2(2.1%) aplastic anaemia, 1(1.08%) leukaemia. Clinical manifestations had 92(100%) pallor, 78(84.7%) weakness and fatigability, 36(39.1%) fever, 26(28.2%) Icterus, 19(20.6%) shortness of breathing, 16(17.3%) hepatomegaly, 14(15.2%) cough, 13(14.1%) history of pica, 12(13%) splenomegaly, 10(10.8%) petechiae, 9(9.7%) vomiting, 9(9.7%) Koilonychias, 5(5.4%) hyper-pigmentation, 6(6.5%) tremors, 21(22.8%) was mild anaemia, 42(45.6%) moderate, 29(31.5%) severe anaemia on the basis of haemoglobin level. This pragmatic study of anemia had iron deficiency was a major cause followed by thalassemia, megaloblastic, acute hemorrhagic sickle cell, aplastic anemia. This study will be helpful to the pediatrician to treat such children efficiently to avoid morbidity and mortality.
Study of depressive illness in retired persons in Maharashtra population
Authors: Qureshi Sadeq Mazhar 
Published: April 2023

As the age advances the myelination of nerve cells degenerate and motor and sensory functions of the brain will start retardation and brain is referred as Fed brain or fatigue brain. After retirement person looses social contact, status or adequate monetary income this will lead to depression. 60 (sixty) retired (elderly) patients with multiple psychiatric illness associated with depression were studied with psychiatric counselling. Their post history and associated medical problems were also recorded and treated accordingly. Different depressive illness include – 23(38.3%) dementia, 14(23.3%) major depression, 11(18.3%) manic, 8(13.3%) anxiety, 4(6.6%) paranoid reaction. Associated medical problems were – 14(23.3%) DM, 21(35%) OA, 8(13.3%) vertigo, 7(11.6%) visual problems, 10(16.6%) constipation The social or family problems were – 17(28.3%) family conflicts, 13(21.6) death of life partner or close relative, 9(15%) sudden loss of job or business, 21(35%) loneliness, 38(61.2%) had suicidal ideation, 22(36.6%) attempted for suicide. The depressive illness of retired or elderly people is quite common psychiatric illness. Apart from the medical treatment, they must be treated with love and affection because patient develops insecurity and loneliness because of retired life.
An assessment of the patient’s understanding and knowledge of the relevance of pre-anesthetic check-up
Authors: Asthana Unnati , Anshumali  , Sharma Shruti 
Published: April 2023

Pre anesthetic checkup is an important prerequisite of any surgery. Therefore the importance of a detailed pre anesthetic check-up including a thorough history and clinical examination should be known to all the patients undergoing any kind of surgery. It can be gauged by the fact that missing out even a single event like a previous drug reaction may jeopardize a precious life.The aim of our study was to assess the understanding of the importance of a pre-anesthetic check-up (PAC) and its components amongst the population coming for elective surgeries in a tertiary care hospital in Urban India.: A prospective randomized observational study was conducted including 450 patients (18-60yrs) coming to a tertiary hospital in a metropolitan city over a period of three months. Each patient was asked to fill out a questionnaire consisting of 16 questions in Hindi (local language)/ English in the waiting area. Every question had multiple possible choices and they had to choose one most appropriate answer according to them. Every correct answer was marked 1 while an incorrect answer was given a score of 0.The data was expressed as percentage and frequency. The correlation tests were applied using the appropriate tests according to the latest SPSS version and included the unpaired t-tests and one way analysis of variance.Out of the 450 patients, only 21.2% had the knowledge of a pre anesthetic clinic. It was also observed that only 19.4% were aware that risk assessment is done in pre anesthetic checkup for undergoing proposed surgery. 54.6% did not know about the importance of optimization before surgery. 99.2% desired to receive information about anesthesia before experiencing.Despite the improved literacy rate, there is a dearth of knowledge about the importance of the pre-anesthetic checkup (PAC) clinic visit before an elective surgery and the role of an anesthesiologist in the perioperative period
Clinicopathological study of swellings of the thyroid gland with an emphasis on multinodular goitre
Authors: Desai Rajendra , Srivastava Rajat , Amenha Chandramala 
Published: April 2023

Many suggest that clinical examination is the best tool to detect the nodules of the thyroid gland. They also suggest that ultrasound of the thyroid gland should be used only to monitor any changes in the size of the nodule of the thyroid. To study swellings of the Thyroid gland with an emphasis on multinodular goitre.The study is prospective, involving all the patients of thyroid swelling. All thyroid swelling cases were subjected to FNAC. The type of thyroidectomy was based on the size and type of thyroid whether neoplastic or non-neoplastic. All the 102 patients were treated by surgeries like hemithyroidectomy, subtotal and total thyroidectomy following FNAC. Majority of the study subjects were in the age group of 20-29 years i.e. 29.5%. In this study most common consistency of thyroid swelling was found to be soft in 61 patients, firm in 22 and hard in 19. Lymph nodes were present in 13 patients (12.75%). 95.1% (97) of patients were euthyroid, four were hypothyroid and one was hyperthyroid. most common FNAC finding was colloid nodule in 61.8% of the cases followed by adenoma in 12.8% of the cases. Most common clinical diagnosis was solitary nodular goitre in 49% of the cases followed by multinodular goitre in 24.5% of the cases. Most common type of surgery performed was Hemithyroidectomy in 50.9% of the cases Most common complication was bleeding which occurred in only three cases. FNAC is a very useful and indispensable test in the diagnosis of thyroid lesions.
Assessment of functional and radiological outcomes of closed reduction and K-wire fixation of supracondylar fracture of humerus in children
Authors: N Ranganath , Choudhary Deelipkumar , Mayi Shivanand C 
Published: April 2023

: Supracondylar fractures of the humerus are commonly seen in children and are difficult to manage because of their unstable nature. It is difficult to maintain the reduction with splints. Non-operative treatment is associated with malunion and open reduction is more invasive procedure. Closed reduction of the fracture with percutaneous K-wire fixation is the preferred procedure with satisfactory results. : Children who came to the tertiary care hospital with a fracture in the supracondylar region following history of trauma to the elbow region and X-ray showing Gartland Type II and extension Type III fractures were included in this study. All these fractures were managed with closed reduction and fixation with K-wires inserted by percutaneous technique. Functional outcome and radiological union were noted.: A total of 35 children were operated. About half of the study population were in the range of 6 to 8 years. Majority of study subjects were boys. The average time period between sustaining a fracture and surgical procedure was 1.35 ± 0.48 days. The final results of this treatment modality were graded based on Flynn’s criteria and about 94.28% of study subjects had excellent to good outcomes. One child had complication of superficial pin tract infection.: Displaced supracondylar fractures of humerus can be effectively managed with closed reduction and percutaneous criss-cross K-wire fixation. This procedure does not disturb the normal fracture healing process.
Perception and preference of health care providers regarding protective role of immunity boosters against Covid -19
Authors: Dashputra Amruta Vishwas , Jaydeep Nayse , R Siddique , Date Amit , Shadama Quazi 
Published: April 2023

Covid -19 caused by a virus to which the people with low immunity response are being affected. Immune boosters play a vital role in protecting human being from various infective organism. The immune boosters include vitamins, minerals, antioxidants, probiotics etc. Indian Government gave emphasis on improving immunity in March 2020. At That time many people started using immunity booster agents. : To study perception and preference of medical teachers about immunity booster agents against Covid -19. A questionnaire based cross sectional study was conducted among medical teachers. Questionnaire was framed in Google form and circulated in social media.Data was noted from excel sheet derived through google form and results were calculated in frequency and percentage, mean &SD. 78% participants were aware about immune boosting agents in initial period of Covid and highest used immune booster agent was Kadha (98%). Participant opined that source of information during this Covid period were Government & WHO guidelines (15%), TV/ newspaper (50%) and social media (41%). Most preferred and convenient to take immunity booster agent was fruits (67%). Reason for high search and use of immunity boosters is that in initial stage of Covid- 19 pandemic, there was theat to life especially in first and second wave of Covid. Along with immune boosters, diet, sleep, exercise and stress reduction are some of the most recommended measures. In present study highest used immune booster agent was Kadha. Allopathic, Ayurvedic and Homeopathic medicine were used as immunity booster agent.
Verity of male sexual disorder videos on social media platforms
Authors: Giri Anant , Gupta Manish , Gupta Hotilal , Sadasukhi Nripesh , Sadasukhi Trilok Chand , Sharma Ashish , Goswami Sonia , Modi Ankit 
Published: April 2023

: Male sexual disorders remain taboo, particularly in a developing country like India. The affected census is under-depicted as of privacy issues, unawareness about the disease complex, a phobia about being affected, and many more counting on it, with advancing digitalization and many friendly social media platform, the affected individual logs onto the cybernet for perception, and here comes the role of content reliability.: In April 2022, we seek the most accountable social media platforms - with keywords of "Male Sexual Disorders", "Erectile Dysfunction", "Premature Ejaculation" and "Male sex Problems" using BuzzSumo, an online analytic tool. The collected content was evaluated by two urology residents on ground of European Association of Urology(EAU) Guidelines 2022, and for discrepancies, the final decision was established by a senior specialist.: Out of 191 included videos, 62.3% were videos uploaded by specialist and their mean duration was 7.2 minutes. 67.53% of uploaded videos explained general information (n=129, 67.53%) and provide information about diagnosis (28.7%) and treatment (78.01%), among which maximum videos favored medical management (97.9%). 158 inclusion videos (82.72%) were following EAU guidelines. In excluded videos, videos on alternative medicines shared maximum number (45.63%). Videos with animation and sound were more appealing based on views and likes, although the contribution of animated videos was rather less in number (25.65%). : The content with delusive information, small size samples, and individual opinion are having more luring appeasement. so, this study firms its ground by stressing verity of content and need for scrutiny by medical community.
Patellar dimensions in south Indian population-An aid to implant design in total knee arthroplasty
Authors: Pothala Sunitha , M Sangeeta , KL Varalakshmi , Afroze M Khizer Hussain 
Published: April 2023

For a successful knee arthroplasty it is imperative to measure patellar thickness intraoperatively to guide the depth of resection. Width thickness ratio of patella is a useful indicator for assessing premorbid patellar thickness. Patellar implants for total knee arthroplasty rely mostly on data from Western population as data from Indian population is sparse. To study the dimensions of patella in South Indian population and to compare it with the previous literature. To estimate the commonest variant of patella in Indian population as per the Weibergs classification.: 101 dry patella from the Department of Anatomy of MVJ Medical College and Research Hospital were used for this study following approval from Instutional ethical committee . The dimensions of patella i.e Patellar height, width, thickness, width of medial and lateral articular facet were measured using Digital Vernier calipers. The results of various statistical parameters (Length, Width, Thickness, MAF and LAF) on the right and left side and combined were expressed in terms of mean and standard deviations along with minimum and maximum values.() The mean height, width and thickness of patella was 39.07mm, 42.56mm and 22.7mm respectively. The values of all the variables of both sides were compared. There was no statistical difference between the variables on right and left sides. Width of MAF in the present study was 19.8 ±2.82 mm while Width of LAF was 24.6±1.88mm. Ratio of width to thickness of patella was 1.8mm. There was no correlation between the two variables.Patella was classified according to Wiberg classification on the basis of dimensions of the width of medial articular and lateral articular facet as well as curvature of the facets. The most common variant observed was Type 2.The knowledge of patellar morphometry will aid the orthopedic surgeons in designing prosthesis. Morphometric data of patella on Indian population will also act as guide for forensic experts and anthropologists in sex determination.
The postoperative analgesic efficacy of Transversus abdominis plane block after caesarean section: A randomized trial
Authors: Choudhary Garima , Kumar Sandeep , Agarwal Aditya 
Published: April 2023

: The present study was conducted to evaluate the postoperative analgesic efficacy of Transversus abdominis plane block after caesarean section and to compare it with patients who were managed conventionally without the TAP Block. The present study was conducted as a comparative study at Department of Anaesthesiology, Hamidia Hospital for a period of 1 year among 100 females undergoing caesarean section. All the selected women were randomly divided into two groups of 50 patients each. Hemodynamic parameters, pain and postoperative analgesic requirement was observed and compared between two groups. : Pain at various interval of time was significantly lower in TAP block group as compared to control group (p&#60;0.01). Mean time to rescue analgesia was 356.44±91.63 min and 95.12± 24.14 min in groups TAP and control groups respectively and the observed difference was statistically highly significant (p&#60;0.001). : TAP block is effective in providing postoperative analgesia among women undergoing LSCS. It is one of the excellent multimodal analgesia technique and significantly reduces the opioid requirements during postoperative period. TAP block was easy to perform, and provided reliable and effective analgesia in this study, and no complications due to the TAP block were detected.
Histopathological spectrum of hyperpigmented skin lesions- A study in a tertiary hospital from western Uttar Pradesh
Authors: Jaiswal Amit , Avani  , Gupta Kamna , Jain Medha , Thakral R.K. , Mohan Alok 
Published: April 2023

Hyperpigmented skin lesions are the cause of concern for general people and are commonest reason for dermatology consultation. An accurate histopathological diagnosis helps a dermatologist in appropriate management of such lesionsA retroprospective study of 100 cases of skin biopsies in hyperpigmented lesions was conducted from January 2020 to July 2021 at our institute. Inadequate skin biopsies, lesions of neoplastic or congenital etiology were excluded from the study. A clinico-histopathological correlation was also done.Out of 100 skin biopsies studied, most cases (50%) were in the age group of 21-40 years. Females were more affected than males; F:M ::1.27:1 and the most common histopathological diagnosis was Lichen planus and its variants (38%).Hyperpigmented skin lesions can be the only presentation of wide variety of the skin lesions. To make the diagnosis;proper and detailed history, clinical examination and microscopic examination of the biopsies is must which helps the doctor to treat the patients effectively.
Efficacy of coblation assisted surgery in obstructive sleep apnea with obstruction at the retropalatal level
Authors: MR Kumar , S Vignesh , NM Babu , A Balakrishnan , SSP Ram 
Published: April 2023

Obstructive sleep apnoea syndrome (OSAS) is a common sleep disorder caused by abnormalities in the pharynx and upper airway muscles. Uvulopalatopharyngoplasty (UPPP) is the commonly indicated surgical procedure for the management of OSA. Recent studies state that coblation assisted UPPP can improve the outcomes of OSA. : To study the efficacy of coblation assisted uvulopalatopharyngoplasty in Obstructive Sleep Apnea Syndrome with isolated obstruction at the retropalatal level. This prospective before-after analysis was conducted in Government Kilpauk Medical College Hospital and Government Royapettah Hospital attached to Kilpauk Medical College from September 2016 to September 2017. After a thorough examination, patients with moderate and severe OSA with obstruction at the retropalatal level were selected for the study. Institutional ethical clearance was obtained and all patients signed the written informed consent form.A total of 25 patients were selected for the study and a male predominance was observed (80%). Tonsil size was graded using the Friedman grading scale and the majority of the patients had grade II tonsillar enlargement (52%). Based on tonsil size and Friedman's palate position, the patients were classified using Friedman's system. 11 patients were classified as stage 1, 10 patients were classified as stage 2, 4 patients were classified as stage 3. A success rate of 68% was observed following surgery based on the 50% reduction in the AHI criterion. Uvulopalatopharyngoplasty is effective in the management of OSA. Coblation assisted procedures can reduce postoperative pain and improve the outcomes of surgical therapy.