bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intraoperative transcutaneous electrical acupoint stimulation combined with anesthesia to prevent postoperative cognitive dysfunction: A systematic review and meta-analysis
Authors: Gan Lin , Qian Kecheng , Yang Jinding , Cai Qian , Ye Qinyu , Dai Mengyuan , Jia Zhaoxing , Jiang Tianxiang , Ma Congcong , Lin Xianming 
Published: January 2025

Background
Postoperative cognitive dysfunction (POCD) is associated with an increased risk of dementia and may lead to chronic neurodegeneration. The utilization of intraoperative Transcutaneous Electrical Acupoint Stimulation (TEAS) in conjunction with anesthesia is expected to become an effective preventive measure for POCD in clinical practice.

Methods
We conducted a comprehensive literature review focusing on the use of TEAS in the prevention of POCD during surgical anesthesia. We searched various databases for relevant literature, including PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure (CNKI), and Wanfang Data. The synthesis of data was performed using RevMan version 5.4.

Results
Our meta-analysis incorporated data from 20 Randomized Controlled Trials (RCTs) involving 1549 patients. The findings revealed that intraoperative TEAS significantly reduced the incidence of POCD when compared to the control group [Odds Ratio (OR) 0.29, 95% Confidence Interval (CI) 0.22–0.39, p < 0.00001]. Moreover, patients receiving intraoperative TEAS exhibited a significant increase in MMSE scores (MD 1.21, 95% CI 0.53–1.89, p = 0.0005). Additionally, intraoperative TEAS demonstrated efficacy in reducing the contents of perioperative serum S100β protein (S100β), neuron-specific enolase (NSE), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) in patients, and the improvement of these indexes may be the potential mechanism of TEAS in preventing POCD.

Conclusion
Our results suggest that intraoperative TEAS combined with anesthesia prevents cognitive dysfunction in the immediate postoperative period, however we need additional evidence of its utility in preventing long-term cognitive dysfunction. We advocate for the broader promotion and application of this approach in clinical surgical settings.

Trial registration
PROSPERO (CRD42023457910).
Topographic changes in macula and its association with visual outcomes in idiopathic epiretinal membrane surgery
Authors: Lee Seung Min , Park Sung Who , Byon Iksoo 
Published: January 2025

Purpose
We investigated changes in macular topography and their association with visual acuity and metamorphopsia in the idiopathic epiretinal membrane (iERM).

Methods
Twenty-four eyes that underwent vitrectomy and ERM removal with internal limiting membrane peeling were included in this study. Best-corrected visual acuity (BCVA) and horizontal/vertical metamorphopsia scores (h and vM-scores in the M-chart) were assessed. The distances of fovea-disc (FD) and fovea-vascular arcade (FV), central subfield macular thickness (CSMT), and foveal location were measured using fundus photography, optical coherence tomography (OCT), and OCT angiography, respectively.

Results
The BCVA (logMAR) and vM-scores (P < 0.001, P = 0.014, respectively) improved after surgery. The distance of the FD decreased (P < 0.001) and FVs increased (P < 0.001, both). The fovea moved horizontally toward the disc (P < 0.001). The change in median total FVs (7.114 mm to 7.369 mm, P = 0.001) correlated with the change in BCVA (P = 0.049, Pearson’s [r] = -0.404). No topographic parameters were associated with an improvement in the vM score.

Conclusions
The macular topography significantly changed after iERM removal; the fovea moved nasally, and the distance between the superior and inferior vascular arcades increased. Such a change was relevant to the improvement in BCVA, but not metamorphopsia.
Evaluation of pre-analytical factors impacting urine test strip and chemistry results
Authors: Bohn Mary Kathryn , Fabros Anselmo , Di Meo Ashley 
Published: January 2025

Abstract

Objectives
Careful consideration of the pre-analytical process for urine examination is essential to avoid errors and support accurate results and decision-making. Our objective was to assess the impact of various pre-analytical factors on urine test strip and quantitative chemistry results, including stability, tube type, fill volume, and centrifugation.

Methods
Residual random urine specimens were identified. Stability of 10 urine test strips and 13 quantitative chemistry parameters were assessed at eight time points (2, 4, 6, 8, 24, 48, 72, and 96 h) at room temperature (RT) and 2–8 °C (n=10–20 samples). The effect of additional pre-analytical variables was assessed, including using preservative tubes for urine chemistry as well as preservative tube underfilling and centrifugation on urine test strip results (n=10 samples).

Results
Seven of the ten urine tests strips evaluated met the minimal agreement criteria for stability (Cohen’s kappa >0.70) across all conditions. A Cohen’s kappa value of <0.70 was observed for pH (48 h), glucose (72 h), and protein (96 h) at RT. All 13 urine chemistry analytes remained stable at defined time points and conditions. Underfilling preservative tubes for urine test strips and centrifugation demonstrated no significant effect. The impact of using preservative tubes for urine chemistry was negligible with the exception of sodium and osmolality.

Conclusions
These findings highlight the pre-analytical factors that impact urine specimen evaluation and may be useful in informing clinical laboratory practices. Acceptable stability window for urine test strips should be considered in the context of the proportion of pathological samples evaluated.
The Story of a Model: The First-Order Diagonal Bilinear Autoregression
Authors: Franses Philip Hans 
Published: January 2025

Abstract
This paper deals with a detailed analysis of the first-order diagonal bilinear time series model, first proposed in Granger and Andersen (1978. An Introduction to Bilinear Time Series Models. Göttingen: Vandenhoeck & Ruprecht). This model allows for sequences of “outliers” in the data. We show that the model has a variety of features that we can observe in practice, while we also document that the bilinear features show up in just a limited number of observations. When the moment restrictions are close, parameter estimation becomes difficult. When the parameters are further away from the moment restrictions, parameter estimation is easy. Yet, in those latter cases, approximative linear models appear to generate equally accurate fit and forecasts. In sum, in cases of proper inference on a bilinear model, the model is barely relevant for forecasting.
Cord blood nucleated red blood cell level: is it a predictive marker for neonatal jaundice?
Authors: Orhon Alper , Topal Hatice , Hakan Nilay , Ozer Esra Arun 
Published: January 2025

Abstract

Background
The aim of this study was to evaluate if the cord blood nucleated red blood cell (nRBC) levels can predict the development of hyperbilirubinemia in healthy neonates.

Methods
All healthy newborn infants born after 35 or more weeks of gestation at our hospital between January 2016 and April 2017 were included. The levels of nRBC were counted in umbilical cord blood samples. Neonates were grouped into two study groups based on the presence or absence of neonatal jaundice.

Results
The study included overall 149 eligible newborn infants. The levels of nRBC and absolute nRBC count showed statistically significant differences between newborns with or without jaundice (p=0.01 and 0.02, respectively).

Conclusions
We suggest that increased nRBC counts in cord blood may be a predictive marker for hyperbilirubinemia in healthy newborn infants.
Protein carbonylation in freshly diagnosed hypothyroidism is independent of thyrotropin levels
Authors: Chandra Kailash , Iqbal Johar 
Published: January 2025

Abstract

Background
Hypothyroidism is a common endocrine disorder with female preponderance. Protein carbonyls (cP) and malondialdehyde (MDA) are generated due to protein and lipid peroxidation, respectively. Oxidative stress (OS) in freshly diagnosed hypothyroidism met with conflicting data in the research. And, a clear relationship between OS and early hypothyroidism is very limited and obscure. Therefore, we aimed to investigate the association between levels of MDA vs. thyrotropin (TSH) and cP vs. TSH among freshly diagnosed hypothyroid subjects.

Methods
We collected blood samples of 80 hypothyroid subjects prior to initiation of thyroxine therapy to know the association between OS and freshly diagnosed hypothyroidism. Serum MDA, cP along with total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C) and triacylglycerols (TG) were quantified in patients as well as 80 age- and sex-matched control subjects.

Results
Levels of MDA and cP were significantly elevated among hypothyroid subjects as compared to control. The rise in MDA levels positively correlated with TSH values among the patients. In addition, cP levels were substantially elevated as compared to MDA values; however, it does not correlate with TSH among hypothyroid subjects.

Conclusions
Our study found no relationship between cP and TSH in freshly diagnosed hypothyroidism. Though it may be due to differential degradation of protein peroxidation products, the mechanism needs further elucidation in future studies.
Saliva and serum ghrelin and obestatin in iron deficiency anemia patients
Authors: Ugur Kader , Aydin Suleyman , Donder Emir , Sahin İbrahim , Yardim Meltem , Kalayci Mehmet , Gozel Nevzat , Ulu Ramazan , Dag Muhammed Sait , Sarikaya Murat 
Published: January 2025

Abstract

Background
Serum ghrelin level is also associated with iron deficiency anemia (IDA), but no study has yet been published on the obestatin level in patients with IDA, even though both hormones are a single gene product. Therefore, the purpose of this investigation was to determine whether there is a link between IDA and these two hormones among other hematological parameters in patients with IDA.

Methods
To measure ghrelin and obestatin, human saliva and serum were collected from 30 women with IDA and 30 control women with repeated collection of samples over a period of 1 week and 1 month. Saliva and serum ghrelin levels were measured by enzyme-linked immunosorbent assay.

Results
Saliva and serum ghrelin and obestatin levels were significantly lower in the IDA group compared with controls; these levels increased slightly above baseline with iron treatment, but remained below the control values. Serum hemoglobin (Hb), ferritin and hematocrit (Hct) levels significantly increased with iron treatment, while total iron-binding capacity (TIBC) decreased compared to baseline concentrations.

Conclusions
The findings suggest that IDA might be linked to imbalance of circulating (serum) and non-circulating (saliva) ghrelin and obestatin levels. Using saliva in place of serum for monitoring the two hormones should minimize inconvenience and patient discomfort.
Oxidative and nitrosative stress in patients with ischemic stroke
Authors: Dogan Ozlem , Kisa Ucler , Erdemoglu Ali Kemal , Kacmaz Murat , Caglayan Osman , Kurku Huseyin 
Published: January 2025

Abstract

Background
Oxidative and nitrosative stress is well believed to play a role in the pathogenesis of ischemic stroke. This study aims to evaluate the time course of oxidative and nitrosative stress in ischemic stroke.

Methods
In total, 27 healthy individuals, 22 individuals with high risk of ischemic stroke due to hypertension and diabetes mellitus, and 20 patients with acute ischemic stroke hospitalized at the Neurology Department of the Kırıkkale University School of Medicine were enrolled in the study. Venous blood was collected at admission (hour 0) and again at hours 24, 48, 72, and 96. Nitric oxide (NO), malondialdehyde (MDA), total oxidative stress (TOS), oxidative stress index (OSI), and total antioxidant status (TAS) were measured and compared among stroke patients and control groups.

Results
Blood NO was significantly higher in the patient group at 0, 24, 48, and 72 h compared to the healthy and high-risk control groups, and lower at 96 h than at early times within the patient group (p<0.001). MDA was higher in patients than the healthy control group at all times. Conversely, TOS and OSI were significantly lower in the patient group than the healthy control group at 96 h and the high-risk control group at 72 and 96 h (p<0.05). There was a significant correlation between initial NO (0 h) and duration of hospitalization (r=0.71; p=0.0003).

Conclusions
These findings suggest a substantial early increase in oxidative and nitrosative stress in ischemic stroke patients during the first 2 days post-admission. However, TOS was lower by days 3–4, likely due to pathological recovery and local/systemic defense systems. The correlation between elevated serum NO during the acute phase of stroke and duration of hospitalization suggests NO as a potentially valuable predictor of ensuing oxidative damage and clinical outcome.
Antidiabetic phytochemicals: an overview of medicinal plants and their bioactive compounds in diabetes mellitus treatment
Authors: Ashagrie Yenework Nigussie , Chaubey Kundan Kumar , Tadesse Mesfin Getachew , Dayal Deen , Bachheti Rakesh Kumar , Rai Nishant , Pramanik Atreyi , Lakhanpal Sorabh , Kandwal Anuj , Bachheti Archana 
Published: January 2025

Abstract
Diabetes mellitus (DM) is a group of metabolic disorders characterized by hyperglycemia due to insufficient insulin secretion or action. Contributing factors include genetic predisposition, obesity, family history, inactivity, and environmental risks. Type 2 diabetes mellitus (T2DM), the most common form, involves impaired insulin secretion by pancreatic β-cells, leading to insulin resistance. By 2045, it is projected that India and China will have approximately 134.3 and 110.8 million diabetic individuals, respectively. Although synthetic drugs are effective in managing DM, they often come with side effects. Consequently, plant-based phytochemicals with antidiabetic properties are gaining attention. Research indicates that around 115 medicinal plants (MPs) have antidiabetic effects, particularly those from the Fabaceae, Liliaceae, and Lamiaceae families. Bioactive compounds like alkaloids, triterpenoids, flavonoids, and phenolics are known to combat DM. Traditional medicinal systems, particularly in developing countries, offer effective DM management. This review highlights the importance of MPs and their bioactive compounds in treating diabetes and underscores the need for further research to commercialize plant-based antidiabetic drugs.
OS GAÚCHOS: CULTURA E IDENTIDADE MASCULINA NO PAMPA
Authors: Fachel Leal Ondina 
Published: January 2025

Este artigo é um resumo de minha etnografia sobre os gaúchos – gaúchos tomados na acepção restrita do termo – vaqueiros, trabalhadores rurais e da pecuária extensiva da região do pampa latino-americano. Esta etnografia foi elaborada há cerca de trinta e cinco anos, os dados são, portanto, datados, coletados em um período específico, mas que, no meu entender, preservam a qualidade e o rigor do fazer etnográfico, buscando dar conta de um determinado sistema cultural em um período histórico específico. Para transformar a etnografia original, que priorizava sobretudo a densidade dos dados, em um artigo curto foi preciso fazer escolhas e cortes. Inicio o presente artigo com uma rápida revisão da literatura antropológica clássica para indicar como o Sul – o gaúcho e o seu território – foram se constituindo como uma área cultural legitima. Depois, busco dar conta desta dinâmica em que identidade e cultura gaúcha se sobrepõem à identidade de gênero. Escolho três eventos para analisar mais detidamente: os causos de galpão, as rinhas de galo e o suicídio campeiro. Tomo aqui estas práticas como narrativas desta cultura a respeito dela própria, como relatos sociais exemplares dos gaúchos sobre si mesmos.AbstractThis article is an abbreviated account of my ethnography about Gauchos – taken in the strict sense of the term – cowboys, rural workers from the extensive cattle ranching in the pampas of South America. This ethnography was written more than thirty years ago, therefore the data presented here has been collected in a specific time period. In order to maintain the quality and rigor of the ethnographic data about a given cultural system, and transform the original ethnography into an article, it was necessary to make many choices and cuts. Here, first, I make a rapid revision of the classical anthropological literature that takes the South – the Gaucho and its territory – as a cultural area. Then, I address this dynamic where Gaucho identity and culture also overlaps male identity and culture, through the account of three situations: their oral culture, taken as speech events; cockfights; and their death tales and suicide practices. I see these situations as narratives of how the Gauchos themselves shape, present and celebrate their own identity.
CAMBIOS Y TRANSFORMACIONES CONTEMPORÁNEAS, PUNTOS DE VISTA Y OTRAS MANERAS DE COMER - UNA ENTREVISTA CON JOAN RIBAS.
Authors: De Oliveira Anelise Rizzolo 
Published: January 2025

Joan Ribas es profesor de antropología del Departamento del Antropología Social en el Campus de la Alimentación Torribera de la Universidad de Barcelona y codirector del ODELA - Observatorio de la Alimentación, que es un grupo de investigación interdisciplinar especializado en la gestión del conocimiento sobre la alimentación y salud.Hoy es profesor asociado y tiene como líneas de investigación: movimientos migratorios y comportamientos alimentarios; turismo, patrimonio e inventario alimentario; câmbios y continuidades de los comportamentos alimentarios.Imparte clases de antropología y psicología del comportamiento alimentarios para los grados en Ciencia y Tecnología de los Alimentos y, en Dietética y Nutrición Humana; Alimentación y Inmigración para los grados en Dietética y Nutrición Humana; y Antropología y Psicología de la Alimentación y de la Gastronomía, para el grado en Ciencias Culinarias y Gastronómicas.Esta entrevista hace parte integrante del postdoctorado en antropología de la alimentación en el Observatorio de la Alimentación – ODELA de la Universidad de Barcelona. Su objetivo es compartir la visión y trabajo de Joan Ribas a cerca de algunos rasgos contemporáneos de la antropología de la alimentación. Tanto la entrevista como su publicación han sido hechas en español para mantener la originalidad, expresividad y significado de la lengua. Es decir, con el mínimo posible de alteraciones en el habla del entrevistado.
Novas faces do mundo. Máscaras e materialidades em tempos de pandemia da COVID-19.
Authors: Silva Adriana Fraga da 
Published: January 2025

O texto trata das novas faces do mundo contemporâneo, um mundo pandêmico pela ação do novo coronavírus e a expansão da COVID-19. Na atual conjuntura o mundo reescreve sua face para além de uma necessária reestruturação econômica, pois estamos diante uma crise civilizacional e sanitária gerada por um modo de vida centrado num sistema gerador de desigualdades e pautado pela exclusão de classe, raça e gênero. A emergência de uma nova normalidade para tempos de pandemia e pós-pandemia carrega novas materialidades, novas relações sociais e descortina desigualdades historicamente postas. As novas materialidades apresentam diferentes camadas através das quais podemos considera-las. Mencionamos aspectos econômicos, variabilidade estética, empatia, sentido de coletividade e desigualdade social por meio das máscaras de proteção individual em tecido.
Discrimination from a Criminological and Criminal-Political Perspective
Authors: Sitarz Olga 
Published: January 2025

Abstract
The subject here is the phenomenon of discrimination from the perspective of criminology, victimology and the tasks of criminal policy. The author first reconstructs the definition of discrimination and its causes, manifestations and negative consequences for people affected by discrimination. The issue of regulating manifestations of discrimination through criminal law regulations is then analysed. Ultimately, the belief is put forward that criminology and victimology provide material to recognize the real social harm of an act in the form of discrimination and unequal treatment in access to social goods. The findings in the area of criminal and criminalization policy make it possible to recognize that other criminalization prerequisites have been fulfilled. This finally makes it possible to call for the introduction into the petty offences law of a prohibited act in the form of unjustified refusal to provide a service that is within the scope of a given actor’s offer.
Control of Poaching in Poland as a Form of Implementation of the Agenda for Sustainable Development 2030
Authors: Dajnowicz-Piesiecka Diana 
Published: January 2025

Abstract
This article’s purpose is to present how the goals of the Agenda for Sustainable Development 2030 are implemented in Poland in terms of combating poaching. It discusses which services combat poaching in Poland and how they operate. The characteristic methods of legal sciences and criminology, namely literature analysis and criticism, the dogmatic method, secondary data analysis, and the interview method, were used to achieve the research goals. The first of these was used to analyse the scientific literature on poaching published to date, with a particular focus on the poaching of land animals. The dogmatic method was used to examine selected legal acts regulating poaching. The dogmatic and literature analysis methods were often applied simultaneously, which allowed interpretation of the regulations analysed. The secondary data analysis consisted of analysing statistics on poaching, specifically criminal statistics obtained from police headquarters. The final research method used were interviews carried out using a computer-assisted individual interview technique. Interviews were conducted with an employee of the Regional Directorate of State Forests in Białystok and an officer of the State Hunting Guard in Białystok, because both institutions are statutorily obliged to combat poaching in Poland.
Integrating Routine Activity Theory and Transparency in Governance for Food Security through the Example of Operation Opson
Authors: Marzęda-Młynarska Katarzyna 
Published: January 2025

Abstract
This article explores the integration of criminology into food security policies through the lens of Routine Activity Theory (RAT) and transparency in governance, with a specific focus on Operation Opson. Food-related crimes, including fraud, theft, and contamination, pose significant threats to global food security and the achievement of Sustainable Development Goal 2: Zero Hunger. The study develops an integrated framework combining RAT and transparency to identify, prevent, and respond to food-related crimes, ultimately strengthening food security. RAT helps map out the food supply chain’s vulnerabilities, identifying motivated offenders, suitable targets, and the absence of capable guardians. Transparency in governance enhances accountability and public trust by making regulatory processes and results openly accessible. The case study of Operation Opson, a joint initiative by Interpol and Europol, illustrates the practical application of this framework. The findings underscore the importance of incorporating criminological insights into food security strategies to achieve zero hunger by 2030, promoting a more secure and resilient global food system.