bluuebunny/crossref_metadata_2025_split huggingface dataset:
Establishing the Profile of Eye Diseases Among Elderly Patients Attending a Tertiary Hospital in Northern, Malawi.
Authors: Banda Owen , Mzumara Thokozani , Ogbonna Grace 
Published: June 2023

Abstract

Background: Globally, there has been a dramatic increase in the geriatric population. Sadly, this populace is highly prone to develop various ocular morbidities.
Aim: To determine the distribution of ocular morbidities among elderly.
Methods: This was a retrospective cross-sectional study conducted at Mzuzu Central Hospital in Malawi. We retrieved data from the hospital’s ophthalmology out-patient registry from January 2021 to December 2021. A non-probability census sampling technique was used to recruit 970 elderly patients. Data entry and analysis was done employing SPSS (v.26)
Results: More males than females had ocular morbidities. Cataract 400 (41.2%) was the most prevalent ocular morbidity followed by glaucoma 189 (19.5%), pinguecula 48 (4.9%) and allergic conjunctivitis 43 (4.4%). Majority of patients were attended to in July. Outer segment diseases were common. The prevalence of cataract, glaucoma, refractive error and allergic conjunctivitis was significantly associated with sex (p<0.05). Age association was found with the prevalence of cataract, glaucoma, pinguecula, allergic conjunctivitis and corneal scar (p<0.05).
Conclusion: The pattern of eye diseases is endemic to the country. More resources should be targeting cataract and glaucoma among the age group.
Effect of phosphate on the adsorption of cadmium on iron and manganese oxides: a comparative study of goethite, ferrihydrite, and potassium manganese materials
Authors: TANG Xuefang , Fayan JIANG , ZHANG Shizhou , WU Yong 
Published: June 2023

Abstract
Iron and manganese oxides participate in a variety of geochemical processes, controlling element cycling and soil quality. The co-adsorption properties of heavy metal cations and oxyanions on iron (manganese) oxides contribute to our understanding of these processes and the ions’ distribution and transformation in geological environments. In this study, ferrihydrite (Fh), goethite (Gt), and manganese oxide (K-MnO2) were prepared by X-ray diffraction (XRD). Fourier transform infrared spectroscopy (FTIR), and Brunauer-Emmett-Teller (BET) Surface analysis were used to characterize the minerals. The Zeta (ζ) potential and zero potential point (pHIEP) were measured by a potential analyzer, and cadmium ions and oxygen anions (phosphate) were tested for ferrihydrite (Fh) and goethite (Gt). The adsorption behavior of manganese oxide (K-MnO2) was studied, and the pH change characteristics of the system before and after adsorption were analyzed. The results show that the maximum adsorption rate of K-MnO2 to Cd2+ (pH = 4, Cd2+20 mg·L− 1) is approximately 95%. After adding phosphate, the adsorption rate of K-MnO2 to Cd2+ increases significantly; the adsorption rate was close to 98% when pH = 4, and phosphate improved the process of K-MnO2 adsorption to Cd2+ reaching equilibrium. Goethite and ferrihydrite have similar adsorption trends for Cd2+ after adding phosphate. When pH = 2-3.5, the adsorption rate for Cd2+ is approximately 10–30%. When original pH is 3.5-5, the pH value of the reaction system is almost higher than 6 when the adsorption end point is reached, and the adsorption rate is already close to more than 95% at pH 7. The addition of phosphate enhanced the equilibrium process of Cd2+ adsorption on goethite ( or ferrihydrite ).
Effect of phosphodiesterase type 5 inhibitors on surgical outcome of ventricular septal defect and pulmonary hypertension patients; a randomized controlled trial
Authors: Shams Khaled A. , Ellahony Dalia Monir , Halima Ahmed Fouad , Elzayat Rania Salah 
Published: June 2023

Abstract
Childrens with ventricular septal defect (VSD) and large systemic-to-pulmonary shunts eventually develop pulmonary hypertension (PH). The perioperative management of patients with VSD and PH is quite troublesome and still debatable, especially in developing countries where the different management options and standardization of treatment is not available. Oral phosphodiesterase type 5(PDE-5) inhibitors are good treatment option being widely available, cheap, of easy administration and does not require extensive monitoring. The aim of our study was to evaluate the effect of the PDE-5 inhibitors when given orally, early pre-operative and continued for 3 months postoperative on controlling post-operative PH with its effect on right ventricle (RV) functions. Fifty-one patients were randomly assigned to either Sildenafil or Tadalafil, 1 week before and continued for 3 months after corrective surgery. The control group received a placebo. There was no significant difference in the improvement in the RVSP between both groups, early in the post operative period (P = 0.255) and on follow up (P = 0.259). there was also no significant difference in the changes in mPAP, post-operatively and on follow up (P = 0.788 and 0.059 respectively). There was a drop in RV functions in both groups post-operatively which improved on follow up, however it was not significant between both groups. The length of ICU stay was similar between both groups (P = 0.143). Peri-operative administration of PDE-5 inhibitors does not have an impact on the clinical course as regard improvement in PA pressure, ventricular functions and ICU stay.
A Bibliometric Analysis and Review of Trends in Erosion and Sedimentation studies
Authors: Chakraborty Arijit , Raj Ravi , Chakma Sumedha , Saharia Manabendra 
Published: June 2023

Abstract
Erosion and sedimentation in streams, lakes, reservoirs, and watersheds are a global issue. Runoff and flood waves erode soil and streambank material, destroying agricultural land. Erosion and sedimentation in water bodies induce soil loss in the watershed and diminish channel flow depth and conveyance. Agricultural runoff can pollute aquatic ecosystems by carrying sediment. As per IPCC 2019 report, in tropical and subtropical regions, the impacts of soil erosion can be observed from the high rates of soil loss, in some cases exceeding 100 t/ha/yr. Therefore, it becomes necessary to address the problem of erosion and sedimentation with serious concern. This paper focuses on highlighting the research advancements in the field of erosion and sedimentation phenomenon, estimation of erosion and sedimentation rate in watersheds, streams and reservoirs and resulting impact assessment from reach scale to watershed scale in last five decades and assessing further research scope in this regard. A bibliometric analysis considering 1000 research articles database extracted from the Web of science has been conducted in the Biblioshiny platform using the R-programming tool. The Bibliometric analysis shows an annual scientific production growth of 2.27% in the field of erosion and sedimentation. Most of the articles have been published in the USA, followed by China, UK, and Belgium. This is the first such bibliometric analysis of erosion and sedimentation together considering one thousand articles associated with it. The study can help in observing the publication trend and identifying the recent emerging topics for research in the field of erosion and sedimentation.
Stability Analysis of New Generalized Mean-Square Stochastic Fractional Differential Equations and Their Applications
Authors: Khan Tahir Ullah , Markarian Christine , Fachkha Claude 
Published: June 2023

Abstract
Stability theory has significant applications in technology, especially in control systems. On the other hand, the newly-defined generalized mean-square stochas-tic fractional (GMSF) operators are particularly interesting in control theory and systems due to their various controllable parameters. Thus, the combined study of stability theory and GMSF operators becomes crucial. In this research work, we construct a new class of GMSF differential equations and provide rigorous proof of the existence of their solutions. Furthermore, we investigate the stability of these solutions using the generalized Ulam-Hyers-Rassias stability criterion. Some examples are also provided to demonstrate the effectiveness of the proposed approach in solving fractional differential equations (FDEs) and evaluating their stability. The paper concludes by discussing potential applications of the proposed results in technology and outlining avenues for future research.
MSC Classification: 34A08 , 34B15 , 34B27
Evaluation of Serum Levels of Soluble Triggering Receptor Expressed on Myeloid Cells-1 in Patients with Vitiligo using Luminex-Based Assay
Authors: Sandes Isis Lustosa Lacrose , Almeida Isabella Barros , Menezes-Silva Lucas , Bomfim Lays Gisele Santos , Gomes Isla Alcântara , Santos Priscila Lima dos , Oliveira Pedro Dantas , Santos Márcio Roberto Viana dos , Quintans-Júnior Lucindo José , Martins-Filho Paulo Ricardo , Araujo Adriano Antunes Souza , Nunes Paula Santos , Moura Tatiana Rodrigues 
Published: June 2023

Abstract
Vitiligo is a chronic acquired disorder characterized by skin depigmentation, and its pathogenesis remains poorly understood. The identification of reliable biomarkers is crucial for enhancing our understanding of the disease and developing effective therapeutic strategies. Triggering Receptor Expressed on Myeloid Cells-1 (TREM-1) is a cell surface receptor constitutively expressed in neutrophils and monocytes, playing a significant role in amplifying and regulating the inflammatory response. However, its role in vitiligo remains unknown. In this context, we aimed to investigate the levels of soluble form of TREM-1 (namely sTREM-1) and inflammatory cytokines involved in the pathogenesis of vitiligo. To the best of our knowledge, this is the first study to investigate the levels of sTREM-1 in patients with the disease. Blood samples were collected from 19 vitiligo patients and 10 healthy individuals as a control group. We used the ProcartaPlex Multiplex Immunoassay kit (Thermo-Fisher Scientific, MA, USA) and the Luminex® 100/200™ System (Luminex Corp., Texas, USA) to measure IL-8, IL-17A, IL-33, IL-10, TNF-α, and sTREM-1 in the serum of both groups. The results demonstrated significantly elevated levels of sTREM-1, IL-17A, and IL-33 in vitiligo patients compared to the control group. Additionally, positive correlations were observed between sTREM-1 and IL-8 and IL-10, suggesting a potential role of sTREM-1 in the inflammatory process associated with vitiligo. These findings provide insights into the pathogenesis of vitiligo and highlight the potential of sTREM-1 as a biomarker for disease activity and therapeutic targeting.
Analysis of postoperative complications of orbital fracture
Authors: Jinhai Yu , Qihua Xu , Hongfei Liao , Yaohua Wang , Chao Xiong , Puying Gan 
Published: June 2023

Abstract

Objective
To analyze the types and causes of complications after orbital fracture reconstruction, and improve the ability of clinicians to control or prevent orbital fracture complications.
Methods
A retrospective case series analysis was conducted, and the clinical data of patients with orbital fractures who were treated in the Affiliated Eye Hospital of Nanchang University from May 2012 to May 2022 and underwent surgical treatment were collected and analyzed retrospectively. Descriptive statistics were used to record the common postoperative complications and follow-up was done, and the complications that still existed after at least 6 months of follow-up were recorded.
Results
Among the 227 patients who underwent orbital fracture surgery, they were followed up for 6–36 months, and complications occurred in 15 cases, with an incidence rate of 6.61%. Among them, implant material infection and rejection occurred in 4 cases, persistent diplopia occurred in 3 cases, intraorbital hematoma occurred in 2 cases, epiphora occurred in 2 cases, lower eyelid eversion or retraction occurred in 2 cases, and skin scars occurred in 2 cases. The main reason for postoperative infection is chronic inflammation in the paranasal sinuses or closed cavity in the fracture area. Postoperative complications of orbital fractures are related to various factors such as the timing of surgery, surgical approach, repair materials, surgical skills, and surgical auxiliary techniques.
Conclusion
Standardizing the operation method and applying precise auxiliary technology may help to reduce the occurrence of complications and improve the success rate of the operation.
Single-cell and transcriptome analysis reveals TAL cells in diabetic nephropathy
Authors: Zhang Chengyu , Li Han , Wang Shixiang 
Published: June 2023

Abstract
Diabetic nephropathy is a global public health concern with multifaceted pathogenesis, primarily involving hypertension. Excessive activation of AT1R has been strongly associated with hypertension onset and progression in diabetic nephropathy. This study aimed to conduct thick ascending limb cell single-cell and transcriptomic analysis in diabetic nephropathy, including screening for biological markers, cellular communication, and immune infiltration, to identify potential biomarkers and effective means for prevention and treatment. By using high-dimensional weighted gene co-expression network analysis, Least Absolute Shrinkage and Selection Operator, machine learning, neural deconvolution, quasi-chronological analysis, Non-negative Matrix Factorization clustering, and Monocyte Chemotactic Protein-induced Counter, we identified 7 potential thick ascending limb cell biomarkers for diabetic nephropathy and elucidated the Bone Morphogenetic Protein pathway's regulation of thick ascending limb cells through podocyte epithelial cells and podocyte cells. The study also highlighted the role of COBL, PPARGC1A, and THSD7A in Non-negative Matrix Factorization clustering and their relationship with thick ascending limb cell immunity in diabetic nephropathy. Our findings provide new insights and avenues for managing diabetic nephropathy, ultimately alleviating the burden on patients and society.
A lightweight method for real-time monitoring of lump coal on mining conveyor belts
Authors: Wu Ligang , Chen Le , Zhang Liang , Shi Jianhua 
Published: June 2023

Abstract
During the transfer of coal using mining conveyor belts, broken coal and lump coal are typically present, along with a few larger pieces of coal. These larger pieces can pose a safety risk during transportation, making it crucial to monitor the lump coal in real-time throughout the process. To solve the above problems, this paper proposes the real-time monitoring method Ghost-SE-Bi FPN (GSB) YOLOv5. First, for data pre-processing, we enhance the contrast of the dataset using adaptive histogram equalization. To further enrich the dataset, we combine Mosaic multi-data enhancement techniques. Second, in this paper, we introduce Ghost Net, a lightweight neural network that performs feature extraction and fusion. This reduces the computational complexity of the model while maintaining its performance. We also incorporate the Squeeze-Excitation attention mechanism to improve feature extraction and weight adjustment, which accelerates model convergence. Finally, in order to efficiently complete multi-source information fusion, a weighted bidirectional feature pyramid is employed to fuse features of varying resolutions. According to the experimental results, the GSB YOLOv5 algorithm has been improved to reduce the number of network layers by 35.256%. Furthermore, the number of parameters and floating point operations have been reduced by 63.023% and 68.582%, respectively. The model size is compressed from 92.7M to 34.4M. In terms of detection performance, the precision and recall rate of the model detection improved by 1.421% and 1.460%, respectively. Additionally, the real-time detection efficiency increased from 68.34 FPS to 107.91 FPS. These findings demonstrate that GSB YOLOv5 not only achieves lightweight, but also effectively enhances various detection performance of the model.
HybridTransferNet: Advancing Soil Image Classification through Comprehensive Evaluation of Hybrid Transfer Learning
Authors: R Chetan , V Ashoka D , V Ajay Prakash B 
Published: June 2023

Abstract
Soil image classification is an important task in agricultural and environmental applications. With the advent of deep learning, image-based soil classification has become a popular research topic. Transfer learning is a widely used approach in image classification, where a pre-trained model is fine-tuned on a new dataset. However, traditional transfer learning approaches only fine-tune the last layer of the pre-trained model, which may not be sufficient for achieving high performance on a new task. In this paper, we propose HybridTransferNet, a novel hybrid transfer learning approach for image-based soil classification. HybridTransferNet fine-tunes a small number of earlier layers in addition to the last layer of a pre-trained ResNet50 model, resulting in improved classification performance compared to traditional transfer learning approaches. We evaluate HybridTransferNet on a soil classification dataset and report multiple performance metrics, including accuracy, precision, recall, and F1 score. Our experimental results show that HybridTransferNet outperforms traditional transfer learning approaches and achieves state-of-the-art performance on the soil classification task.
An Experimental Study of the Heavy Hydrocarbon Impact on Phase Behavior of Hydrocarbon Mixtures
Authors: Buleiko V.M. , Buleiko D.V. 
Published: June 2023

Abstract
It is of much interest to study an impact of heavy hydrocarbons on the phase behavior of hydrocarbon mixtures. Using a method of the precision adiabatic calorimetry the phase equilibria in quaternary mixtures of methane, propane, octane, and nonane have been studied. The phase diagrams for investigated mixtures have been plotted based on the experimental data. The phase transitions were localized by the finite discontinuities in temperature derivatives of the thermodynamic potentials. The heat capacity, internal energy, pressure, and temperature derivative of pressure at constant volume were measured in the range 170–320 K, up to 40 MPa. Quaternary mixtures as quasi-binary mixtures are presented. The first quasi-component of the quasi-binary mixture is a binary mixture with the constant methane/propane ratio. The second quasi-component of the quasi-binary mixture is a binary mixture of octane and nonane. Investigated hydrocarbon system is a combination of the simple hydrocarbon mixtures for the low concentration of octane and nonane. In the earlier papers we presented the simple hydrocarbon mixtures for the low concentration of octane, nonane, and decane, and quaternary mixtures of methane, propane, octane, and decane for the low concentration of octane and decane, which are a combination of the simple hydrocarbon mixtures for the low concentration of octane and decane. Our investigations show that quaternary hydrocarbon mixture for the low concentration of octane and nonane as well as the simple hydrocarbon mixtures for the low concentration of octane, nonane, and decane split into three phases, the octane-nonane-lean macrophase and the microphases formed by octane and nonane. Besides, the heavy components provoke a split of the liquid part of a quaternary mixture into two liquid phases, the octane-nonane-rich phase and the octane-nonane-lean phase.
The nucleolar protein NOL12 is required for 5' end processing of large ribosomal subunit rRNA precursors in Arabidopsis
Authors: Zakrzewska-Placzek Monika , Golisz-Mocydlarz Anna , Krzyszton Michal , Piotrowska Justyna , Lichocka Malgorzata , Kufel Joanna 
Published: June 2023

Abstract
Background
NOL12 5'-3' exoribonucleases, conserved among eukaryotes, play important roles in pre-rRNA processing, ribosome assembly and export. The best described yeast counterpart, Rrp17, is required for maturation of 5.8S and 25S rRNAs, whereas human hNOL12 is crucial for the separation of the large (LSU) and small (SSU) ribosome subunit rRNA precursors.
Results
Here we show that plant AtNOL12 is also involved in rRNA biogenesis, particularly in the processing of the LSU rRNA precursor, 27S pre-rRNA. Importantly, the absence of AtNOL12 alters the expression of many ribosomal protein and ribosome biogenesis genes, which may further exacerbate rRNA biogenesis defects, or, alternatively, may be the effect of the disturbed ribosome assembly caused by delayed pre-rRNA processing. Also, exposure of nol12 mutants to stress factors, including heat, salt and pathogen Pseudomonas syringae, enhances the observed molecular phenotypes, linking pre-rRNA processing to stress response pathways. AtNOL12-dependent aberrant rRNA processing may affect ribosome function, as indicated by improved mutant resistance to ribosome-targeting antibiotics.
Conclusion
The pre-rRNA processing pathway, although extensively studied, is still poorly described in plants. Our work reveals the involvement of AtNOL12 in the 5' end maturation of rRNA precursors, which is related to stress response in Arabidopsis. This contributes to a better characterization of plant ribosome biogenesis.
Alterations in the transcript level of the Contactin Associated Protein 2 gene could conceivably influence verbal Theory of Mind and predict autism spectrum disorder incidence
Authors: Ghamari Rana , Tahmaseb Mohammad , Alizadeh Fatemeh , Mohammadzadeh Azar , Tavakolian Najmeh , Sarabi-Jamab Atiye , Tehrani-Doost Mehdi 
Published: June 2023

Abstract
Objective: Social interaction and communication impairments in autism spectrum disorder (ASD) are supposed to be related to impairments in Theory of Mind (ToM), which is the ability to attribute mental states to oneself and other social agents. Language and ToM are intertwined cognitive components, and higher-order manifestations of the ToM cannot be achieved in the absence of specific language competencies. The gene Contactin Associated Protein 2 (CNTNAP2) is associated with language/verbal skills as well as changes in social cognition. As of yet, no study has assessed the association of CNTNAP2 expression with ASD and ToM. This study aimed at assessing CNTNAP2 expression alterations in ASD individuals and to model ASD and ToM leveraging cognitive and genetic measures.
Method: 43 children and adolescents with high-function autism between the ages of 8 and 18 years old, as well as 44 matched age and sex typically developed (TD) individuals participated in the study. SYBR green Real-time PCR was used to determine CNTNAP2 expression evaluation. To measure verbal and non-verbal ToM, Happe's Strange Stories test and Moving Shapes paradigms were employed. The social responsiveness scale (SRS-2) was also used to assess social functioning. The statistical analysis was performed using a 95% confidence interval.
Results: Compared to TD group, we found a significant downregulation of CNTNAP2 expression in ASD subjects. Moreover, correlation tests and linear regression indicated that there is no significant correlation between cognitive variables and expression of CNTNAP2 in the ASD group. However, the expression of CNTNAP2 in TD was significantly correlated with verbal ToM variables, but not with non-verbal ToM. Finally, the general linear model suggested that non-verbal ToM parameters and CNTNAP2expression could predict ASD, and verbal ToM may serve as a moderator variable for CNTNAP2 expression.
Conclusion: Briefly, we found that CNTNAP2was downregulated in ASD samples compared to TD individuals. Also, our results suggest a molecular-cognitive model for ASD. Further studies should be conducted to determine whether the findings of this study are reliable.