bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diatom–salinity thresholds in experimental outdoor streams reinforce the need for stricter water quality guidelines in South Australia
Authors: Frost Charles , Tibby John , Goonan Peter 
Published: February 2023

AbstractWater quality guidelines are an important tool for managing environmental pressures on freshwater streams, but guidelines are frequently set using conditions from reference sites that are assumed to be unimpacted. Using biological thresholds potentially provides a better foundation for guidelines. However, guidelines based on field observations alone may be compromised by confounding influences. This study used an outdoor stream mesocosm, an artificial substrate (rope), and six salinity concentrations to assess the veracity of a diatom–salinity threshold determined previously in natural temperate South Australian streams. In addition, shaded treatments assessed the synergistic influences of salinity and reduced sunlight. Salinity had the strongest effect on diatoms, influencing both species and functional compositions. Species diversity and richness, and functional diversity had negative correlations with salinity. Shade strongly reduced diatom concentrations and altered species composition, with no observed interaction between salinity and light. Threshold Indicator Taxa ANalysis indicated a salinity threshold of 1610 μS cm−1 for both shade treatments, lower than the upper limit of the range used in current freshwater guidelines. This study recommends a new candidate guideline of 1600 μS cm−1 for regional freshwater streams and suggests that contemporary methods for deriving water quality guidelines may not adequately protect aquatic health.
Automation, organizational ambidexterity and the stability of employee relations: new tensions arising between corporate entrepreneurship, innovation management and stakeholder management
Authors: Hiebl Martin R. W. , Pielsticker David I. 
Published: February 2023

AbstractWhile previous entrepreneurship research has only seldom drawn on organizational ambidexterity, the analysis of the important contemporary tensions among entrepreneurship, innovation management and strategic management issues may be facilitated by more closely analysing organizational ambidexterity in entrepreneurial settings. In this paper, we follow this thinking and more closely analyse an often applied form of corporate entrepreneurship: automation. Such automation is transferring work that was formerly conducted by humans to machines and may thus result in new tensions between corporate entrepreneurship, innovation management and the management of organizational stakeholders such as employees. The present paper investigates whether increased automation lowers the stability of firms’ relationships with their employees. In addition, we expect that this relationship is moderated by organizational ambidexterity, as employees may have perceived ambidexterity as a signal that their firm will not overly invest in exploitation only, but maintain a balance between exploitation and exploration. Drawing on stakeholder theory, previous insights into corporate entrepreneurship and a survey of German Mittelstand firms, our findings show that highly ambidextrous firms are indeed more vulnerable to automation, leading to lower employee relational stability. Our findings thus suggest that in highly ambidextrous firms, novel tensions around automation-related corporate entrepreneurship will be detrimental to the stability of the firm’s relations with one of its key stakeholder groups: employees.
Comment on “Tidally Synchronized Solar Dynamo: A Rebuttal” by Nataf (Solar Phys. 297, 107, 2022)
Authors: Scafetta Nicola 
Published: February 2023

AbstractNataf (Solar Phys.297, 107, 2022) has recently asserted that the hypothesis that the solar dynamo may be synchronized by planetary tidal forces is unsupported by any evidence. He reached this conclusion by adopting a simplistic tidal model (which was discussed in his Appendix A) that relies solely on the effect of Mercury, Venus, Earth, and Jupiter whose orbits were assumed to be circular. His model was unable to produce tides with periods compatible with those of the Schwabe 11-year solar cycle. I demonstrate here that the modeling in Nataf (2022) is erroneous and that a correct modeling and interpretation of the planetary tidal function, which accounts for all planets and their true orbits, fits well with the spectral requirements of the Schwabe 11-year solar cycle. This result has been already shown and discussed in a substantial body of scholarly research on the subject, which Nataf apparently ignored. A recent and extended review of the empirical and theoretical evidences supporting the planetary synchronized solar dynamo theory was offered by Scafetta and Bianchini (Front. Astron. Space Sci.9, 937930, 2022).
Impact of Modern Irrigation Methods on Groundwater Storage and Land Subsidence in High-water Stress Regions
Authors: Abd-Elaty Ismail , Fathy Ismail , Kuriqi Alban , John Am Pris , Straface Salvatore , Ramadan Elsayed M. 
Published: February 2023

AbstractWater resources management in high-stress regions is a large-scale problem affecting food and water security. Therefore, modern irrigation systems such as sprinklers, subsurface, and drip irrigations are applied to manage the water shortage in regions of the Nile delta. Because of the increase in population rate and climate change, freshwater supplies are significantly limited and must be efficiently managed. Consequently, Egypt plans to implement MIS in the old land of the Nile delta. The current study aims to investigate and model the recharge from the excess irrigation system that affects groundwater storage and land subsidence unexpectedly. The visual modflow was applied to investigate the groundwater heads and drawdown. At the same time, the analytical solution based on Terzaghi theory, and the surfer software was used to estimate and map the land subsidence.For this reason, we investigated the groundwater drawdown in the high-water shortage of Egypt’s Nile delta. Three scenarios were considered by changing irrigation methods and their Impact on land subsidence in the Nile Delta Aquifer (NDA). Therefore, the results of this study demonstrated that the groundwater drawdown reached 2.60 m, 4.20 m, and 6.50 m, respectively. In contrast, the land subsidence outstretched 26 m, 44 m, and 65 cm for the sprinkle sub-surface. Future design infrastructures such as pipelines, roads, irrigation networks, canals, and water structures should consider land subsidence due to modern irrigation systems (MIS).
Severe hyponatraemia (P-Na < 116 mmol/l) in the emergency department: a series of 394 cases
Authors: Mustajoki Sami 
Published: February 2023

Abstract
Aim
To evaluate the significance of severe hyponatraemia presented at the emergency department (ED).

Methods
A retrospective hospital
records study of all patients with plasma sodium levels of < 116 mmol/l from 2016 to 2020 in a single tertiary referral centre.

Results
A total of 394 visits of 363 individual severely hyponatraemic patients represented 0.08% of all ED visits. The
mean age was 68 years and the male-to-female ratio was 1:1.3. The symptoms and signs were diffuse and varying, while half of
the patients had neurologic symptoms. The aetiology of hyponatraemia was often multifactorial. The aetiologies varied by age,
and the most common ones were the syndrome of inappropriate antidiuresis (34%), diuretic use (27%), alcohol-related (19%)
and dehydration (19%). The mean sodium correction rates were 6.6, 4.9 and 3.8 mmol/l/24 h at 24, 48 and 72 h, respectively.
The mean maximum correction rate over any 24-h time interval was 10.2 mmol/l. The vital signs (National Early Warning
Score, NEWS) of severely hyponatraemic patients were mostly normal. All-cause mortality was 18% for 1-year follow-up.
Malignancies, especially small-cell lung cancer, and end-stage liver disease caused most of the deaths. Osmotic demyelination
syndrome (ODS) was diagnosed in five (1.4%) patients.

Conclusion
Patients with severe hyponatraemia in the ED presented with non-specific complaints. The aetiology of hyponatraemia was often multifactorial and varied by age. The need
for intensive care was poorly predicted by NEWS. The one-year mortality rate was 18% and the incidence of ODS 1.4% after
an episode of severe hyponatraemia.
Myocardial Metabolism in Heart Failure
Authors: Ng Sher May , Neubauer Stefan , Rider Oliver J 
Published: February 2023

Abstract
Purpose of Review
Myocardial metabolism is intricately linked to cardiac function. Perturbations of cardiac energy metabolism result in an energy-starved heart and the development of contractile dysfunction. In this review, we discuss alterations in myocardial energy supply, transcriptional changes in response to different energy demands, and mitochondrial function in the development of heart failure.

Recent Findings
Recent studies on substrate modulation through modifying energy substrate supply have shown cardioprotective properties. In addition, large cardiovascular outcome trials of anti-diabetic agents have demonstrated prognostic benefit, suggesting the importance of myocardial metabolism in cardiac function.

Summary
Understanding molecular and transcriptional controls of cardiac metabolism promises new research avenues for metabolic treatment targets. Future studies assessing the impact of substrate modulation on cardiac energetic status and function will better inform development of metabolic therapies.
Effect of chilling and salinity stress on photosynthetic performance and ultrastructure of chloroplast in faba beans (Vicia faba L.) leaves
Authors: El-Dakak Rehab A. , Badr Reem H. , Zeineldein Marwa H. , Swedan Eman A. , Batrawy Omnia El , Hassaballah Amany F. , Hassan Ibrahim A. 
Published: February 2023

AbstractChilling (Ch) and salinity (S) are challenging stresses affecting plant physiology, growth, and productivity. The current study investigated the effects of these two stresses, singly and in combination, on photosynthetic performance and ultrastructure of chloroplast of faba beans (Vicia faba L. Cv. Aspani). Plants were exposed to 3 °C and 120 mM NaCl for 16 h in an optimized soil mixture (sand:clay 2:1) under optimized conditions. Results showed that both Ch and S significantly reduced photosynthetic rates, Fv/Fm, chlorophyll content, stomatal index, and stomatal conductance. Chilling caused changes in chloroplast ultrastructure (swelling, ruptured envelopes, and shrunk lamellae), while salinity caused more deformation of the thylakoid membrane and disorganization of the grana structure. However, there was an antagonistic effect between Ch x S. The tolerance of plant to 120 mM NaCl, in the present study, was improved by exposure to Ch which rather allowed the maintenance of chloroplast ultrastructure and morphology of stomata. Moreover, using SEM and TEM gave an effective insight of the ultrastructural damage in plant cells under stress and helps to consider the underlying mechanisms of stress effects. Our results suggest that Ch mitigates the noxious effect of S on the photosynthetic performance of Vicia faba plants.
Glutamine is a substrate for glycosylation and CA19-9 biosynthesis through hexosamine biosynthetic pathway in pancreatic cancer
Authors: Liu Chen , Deng Shengming , Xiao Zhiwen , Lu Renquan , Cheng He , Feng Jingjing , Shen Xuxia , Ni Quanxing , Wu Weiding , Yu Xianjun , Luo Guopei 
Published: February 2023

Abstract
Background
Carbohydrate antigen 19–9 (CA19-9) is the most widely used biomarker for pancreatic cancer. Since CA19-9 closely correlates with patient outcome and tumor stage in pancreatic cancer, the deciphering of CA19-9 biosynthesis provides a potential clue for treatment.

Methods
Concentration of amino acids was detected by ultrahigh-performance liquid chromatography tandem mass spectrometry. Metabolic flux of glutamine was examined by isotope tracing untargeted metabolomics. Label-free quantitative n-glycosylation proteomics was used to examine n-glycosylation alterations.

Results
Among all amino acids, glutamine was higher in CA19-9-high pancreatic cancers (> 37 U/mL, 66 cases) than in CA19-9-normal clinical specimens (≤ 37 U/mL, 37 cases). The glutamine concentration in clinical specimens was positively correlated with liver metastasis or lymphovascular invasion. Glutamine blockade using diazooxonorleucine suppressed pancreatic cancer growth and intraperitoneal and lymphatic metastasis. Glutamine promotes O-GlcNAcylation, protein glycosylation, and CA19-9 biosynthesis through the hexosamine biosynthetic pathway. UDP-n-acetylglucosamine (UDP-GlcNAc) levels correlated with the glutamine influx through hexosamine biosynthetic pathway and supported CA19-9 biosynthesis.

Conclusions
Glutamine is a substrate for CA19-9 biosynthesis in pancreatic cancer. Glutamine blockade may be a potential therapeutic strategy for pancreatic cancer.
Numerical modeling constrained by environmental isotopes for sustainable development of partially renewable aquifers in desert area
Authors: Hagagg Kamilia , Hussien Rasha Abdallah , Sadek Mostafa Abdel Hamid 
Published: February 2023

AbstractSustainable groundwater resources are a critical issue for national development in developing countries like Egypt, which is characterized by a semi-arid to arid climate and low per capita share of fresh water as a result of progressive population increase and especially after the construction of the Great Ethiopian Renaissance Dam. It is mandatory to adopt and modify methods suitable for preserving and efficient use of available water resources. The Eocene carbonate aquifer in the desert area under study (West El-Minia, Mid-Upper Egypt) is partially renewable; its sustainable development in irrigation is explored in this work. The (recharge–withdraw–exploit) regimes have been optimized by keeping the well abstraction below the fraction of renewable recharge and maximizing the exploit by selecting low water -consuming crops of high economic value. A novel approach is introduced in this work by integrating isotope hydrology techniques with numerical modeling; environmental isotopes (18O and D) contents of 62 groundwater samples have been used to determine and map the contribution of recent recharge in the study area (from 10 to 95%) and to constrain the acceptable reduction in hydraulic head allowed under an optimized withdraw and usage regime. Different scenarios were proposed by changing (rate of pumping, number of wells, wells distribution and irrigated crops) and simulating aquifer behavior to achieve the sustainable yield goals and the best plan for groundwater management in the study area.
Graphical abstract
Development and Feasibility Testing of a Multilevel Intervention to Increase Hepatitis C Virus Screening Among Baby Boomers in Primary Care
Authors: Kasting Monica L. , Laily Alfu , Nephew Lauren D. , Shields Cleveland G. , Shedd-Steele Rivienne , Rawl Susan M. 
Published: February 2023

AbstractChronic infection with hepatitis C virus (HCV) results in an increased risk of cirrhosis and hepatocellular carcinoma (HCC). Only 15% of baby boomers (born 1945–1965) have ever been screened. We aimed to develop a multilevel intervention to increase HCV screening for baby boomers in a primary care setting. This study included two phases: intervention development (phase 1) and feasibility testing (phase 2). In phase 1, we partnered with a Community Advisory Board and a Provider Advisory Board to develop a multilevel intervention to increase HCV screening to be delivered to both providers and patients in primary care. Phase 2 assessed intervention feasibility, acceptability, and usability by conducting Concurrent Think Aloud (CTA) interviews and surveys using previously validated scales with patients (n = 8) and providers (n = 7). Phase 1 results: The patient-level intervention included a mailed reminder letter and CDC pamphlet and a 7-min in-clinic educational video. The provider-level intervention included a 30-min educational session and monthly performance feedback e-mails. Phase 2 results: Qualitatively, both the patient and provider-level intervention were feasible, acceptable, and usable by the target audiences. Quantitatively, on a 1–4 scale, the range of patient-level scores was 3.00–4.00 and provider level was 3.50–4.00 for feasibility, acceptability, and usability. This intervention could improve HCV screening among a high-risk population and therefore reduce HCV-related morbidity and mortality. This project developed a feasible, acceptable, and usable multilevel intervention aimed at increasing HCV screening in primary care.
Authoritarian Successor Parties, Supporters, and Protest: Lessons from Asian Democracies
Authors: Lee Myunghee 
Published: February 2023

AbstractAre authoritarian successor party (ASP) supporters more likely to protest? I propose that ASP supporters are less likely to protest in general. The post-democratization mobilization environment is shaped upon the pre-democratization mobilization basis. During the pre-democratization period, protest was organized around the democracy movement. Thus, protest tactics and networks were accumulated through it. As former authoritarian ruling party supporters, ASP supporters are less likely to have legacies of participating in the democracy movement, which prevents them from accessing the accumulated protest resources from the democracy movement. However, I argue that this negative association varies based on the ASP qualities and supporters’ age. Supporters of ASPs that maintain strong pre-democratization legacies are more likely to participate in protests than supporters of ASPs that do not strongly highlight their authoritarian legacies. Also, when the ASPs’ characteristics are considered, older ASP supporters are more likely to participate in protests than younger supporters. Using both single-level and multilevel statistical analyses, I examine four Asian countries with politically powerful ASPs and find evidence supporting my hypotheses. Lastly, I compare two South Korean mass movements, the Candlelight movement and theTaegeukgirallies to unpack the relationships between ASP supporters, protest resources, and mobilization. This study reveals authoritarian legacies among post-democratization citizens through ASP supporters’ protesting behavior.
Effect of three crop rotations and four residue levels on canola and bean grain yield and residue production
Authors: Hirzel Juan , Undurraga Pablo , León Lorenzo , Matus Iván 
Published: February 2023

AbstractCrop rotation in agriculture can lead to increased crop productivity in the rotation and improved soil fertility as a result of residue incorporation. Unfortunately, residue incorporation is not a common practice in crop production systems under the Mediterranean regime, largely due to the lack of information on the effect of the follow-up crops. Therefore, this study was conducted with six biannual rotations (bread wheat–canola, bread wheat–bean, durum wheat–canola, durum wheat–bean, corn–canola and corn–bean) using four residue incorporation levels (0, 50, 100 and 200%) in an Andisol in south central Chile. Grain yield and residue production were evaluated in the canola and bean crops 5 years after initiating crop rotation. The previous crop affected canola grain yield and residue production, which were both higher after corn. Meanwhile, the residue incorporation level had a slight effect on residue production after bread wheat. Only bean grain yield was affected by the previous crop, which was higher after the durum wheat and corn crops. The residue incorporation has marginally affected residue production after bread wheat. Finally, residue incorporation at different levels under the conditions of the present experiment had a minimal effect on bean and canola residue production following the bread wheat crop. The best crop rotation for canola grain yield was corn–canola, which produced 0.54 Mg/ha (18.3%) higher yield than the average of the other two rotations. The best crop rotation for achieving higher bean grain yield was corn–bean, which yielded 0.52 Mg/ha (12.3%) higher than the average of the other two rotations.
Atypical hemispheric lateralization of brain function and structure in autism: a comprehensive meta-analysis study
Authors: Li Qingqing , Zhao Wei , Palaniyappan Lena , Guo Shuixia 
Published: February 2023

AbstractBackgroundCharacteristic changes in the asymmetric nature of the human brain are associated with neurodevelopmental differences related to autism. In people with autism, these differences are thought to affect brain structure and function, although the structural and functional bases of these defects are yet to be fully characterized.MethodsWe applied a comprehensive meta-analysis to resting-state functional and structural magnetic resonance imaging datasets from 370 people with autism and 498 non-autistic controls using seven datasets of the Autism Brain Imaging Data Exchange Project. We studied the meta-effect sizes based on standardized mean differences and standard deviations (s.d.) for lateralization of gray matter volume (GMV), fractional amplitude of low-frequency fluctuation (fALFF), and regional homogeneity (ReHo). We examined the functional correlates of atypical laterality through an indirect annotation approach followed by a direct correlation analysis with symptom scores.ResultsIn people with autism, 85, 51, and 51% of brain regions showed a significant diagnostic effect for lateralization in GMV, fALFF, and ReHo, respectively. Among these regions, 35.7% showed overlapping differences in lateralization in GMV, fALFF, and ReHo, particularly in regions with functional annotations for language, motor, and perceptual functions. These differences were associated with clinical measures of reciprocal social interaction, communication, and repetitive behaviors. A meta-analysis based ons.d.showed that people with autism had lower variability in structural lateralization but higher variability in functional lateralization.ConclusionThese findings highlight that atypical hemispheric lateralization is a consistent feature in autism across different sites and may be used as a neurobiological marker for autism.
Embodied world construction: a phenomenology of ritual
Authors: Williams Jack 
Published: February 2023

AbstractThis article presents a new approach to understanding ritual: embodied world construction. Informed by phenomenology and a philosophy of embodiment, this approach argues that rituals can (re)shape the structure of an individual's perceptual world. Ritual participation transforms how the world appears for an individual through the inculcation of new perceptual habits, enabling the perception of objects and properties which could not previously be apprehended. This theory is then applied to two case studies from an existing ethnographic study of North American evangelicalism, indicating how the theory of embodied world construction can shed new light on how individuals are shaped by ritual practice.
The scaffolded evolution of human communication
Authors: Veit Walter , Browning Heather 
Published: February 2023

Abstract
Heintz & Scott-Phillips provide a useful synthesis for constructing a bridge between work by both cognitive scientists and evolutionary biologists studying the diversity of human communication. Here, we aim to strengthen their bridge from the side of evolutionary biology, to argue that we can best understand ostensive communication as a scaffold for more complex forms of intentional expressions.
The central problem is still evolutionary stability
Authors: Wacewicz Sławomir , Żywiczyński Przemysław 
Published: February 2023

Abstract
We applaud Heintz & Scott-Phillips's guiding metaphor of “unleashing leashed expression,” and we value the unified explanation for the emergence of not only language, but also other forms of unleashed expression, such as multimodal communication. We are more critical of the authors' discussion of the selection pressures acting towards unleashed expression, which are proposed to hinge on partner choice ecology.