bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sustainability reporting – a systematic review of various dimensions, theoretical and methodological underpinnings
Authors: Nasreen Taslima , Baker Ron , Rezania Davar 
Published: January 2023

Purpose
This review aims to summarize the extent to which sustainability dimensions are covered in the selected qualitative literature, the theoretical and ontological underpinnings that have informed sustainability research and the qualitative methodologies used in that literature.

Design/methodology/approach
This study uses a systematic review to examine prior empirical studies in sustainability reporting between 2000 and 2021.

Findings
This review contributes to sustainability research by identifying unexplored and underexplored areas for future studies, such as Indigenous people’s rights, employee health and safety practice, product responsibility, gender and leadership diversity. Institutional and stakeholder theories are widely used in the selected literature, whereas moral legitimacy remains underexplored. The authors suggest that ethnographic and historical research will increase the richness of academic research findings on sustainability reporting.

Research limitations/implications
This review is limited to qualitative studies only because its richness allows researchers to apply various methodological and theoretical approaches to understand engagement in sustainability reporting practice.

Originality/value
This review follows a novel approach of bringing the selected studies’ scopes, theories and methodologies together. This approach permits researchers to formulate a research question coherently using a logical framework for a research problem.
Factors determining the investment behaviour of farmers – the moderating role of socioeconomic demographics
Authors: Manocha Shilpa , Bhullar Pritpal Singh , Sachdeva Timcy 
Published: January 2023

PurposeThe purpose of this study is to investigate the determinants that determine the investment behaviour of rural farmers. This study further examines the moderation effect of socio traits in the association between investment behaviour and its determined factors.Design/methodology/approachThis study used a cross-sectional research design to gather information. The information for this research survey was gathered using a structured questionnaire from 400 individual investors in the rural area of Punjab, who participated in the study. It has been decided to use the Cronbach’s alpha test to determine the validity and reliability of the questionnaire. To evaluate the hypothesis, structural equation modelling has been used in the research process.FindingsThe results of this study reveal that attitude, financial risk inclination, financial planning and investment intention determine the investment behaviour of the rural people of Punjab. The results for the interaction effect of socio traits with investment intention, financial risk propensity and investment attitude were found statistically significant amongst rural people. The results of the moderation effect stated that interaction between the attitude and investment intention and financial risk propensity and investment intention is significantly influenced by age of respondents. The results further reveal that marital status of rural people affect the interaction between attitude and investment intention and financial risk propensity and investment intention. Nothing about education seems to be a moderating influence on any of the relationships studied.Originality/valueThe authors contribute to the literature in two aspects. Firstly, to the best of the authors’ knowledge, this is the only study of its kind that focuses on the investment behaviour of farmers. Secondly, by looking at the farmer’s investing behaviour, the moderation effect of demographic variables is also studied which set this study apart from another existing scholarly research. This study contributes to the growing literature on investment behaviour of farmers in developing and developed markets.
Just one screen is not enough: Social TV role to Brazilian fans of Major League Soccer
Authors: Moura Bruno Melo , de Souza-Leão André Luiz Maranhão , Silva Ewerton Pacheco da , Santos Guilherme Monteiro Alves dos 
Published: January 2023

PurposeSports leagues, such as Major League Soccer (MLS), aim at expanding their audience at global level through alternative media other than television (TV). Brazil stands out among football media consumer audiences as one of the main markets worldwide. Brazilian MLS consumers play the role of fans to converge between TV media and digital platforms, in a phenomenon that has been called Social TV.Design/methodology/approachThe aim of the current research is to investigate how Brazilian MLS fans' consumption process is established through Social TV; it was done based on netnography performed between 2018 and 2020.FindingsResults have indicated that Social TV is a catalyst of practices associated with fan culture: cultural convergence, technologies appropriations, poaching experiences and production of a collective intelligence.Research limitations/implicationsCurrent research reinforces how ethnography methodology has been gaining room as likely consumer market research, working as alternative method based on the prevalence of focus group and survey techniques.Practical implicationsSocial TV phenomenon presents itself as a possibility to expand and direct marketing strategies focused on sports management, just as the media often consumed by fans.Originality/valueFrom the results, it is possible assuming that connections between fans are punctually guided by their relationship with the cultural object consumed by them in a network relationship whose actors deindividualize sociocultural practices such as consumption. Thus, the main contribution of the study lies on identifying how fan culture can be autonomously established in the market arena in comparison to other cultures.
A novel toxin–antitoxin system swpAB alters gene expression patterns and reduces virulence expression in enterohemorrhagic Escherichia coli
Authors: Ebihara Shinya , Yen Hilo , Tobe Toru 
Published: January 2023

AbstractToxin–antitoxin (TA) systems are found widely among many bacteria, including enterohemorrhagic Escherichia coli (EHEC), but their functions are still poorly understood. In this study, we identified and characterized a novel TA system belonging to the relBE family, classified as a type II TA system, found in EHEC. The protein encoded by the toxin gene is homologous to RelE ribonuclease. Using various conditions for increasing the toxin activity, high‐level induction of a toxin gene, and repression of an antitoxin gene in wild‐type EHEC, we showed that the TA system, named swpAB (switching of gene expression profile), is involved in selective repression of a set of genes, including some virulence genes, and in the reduction of adherence capacity, rather than in suppression of bacterial growth. A detailed analysis of the profiles of RNA levels along sequences at 15 min after high expression of swpA revealed that two virulence genes, espA and tir, were direct targets of the SwpA toxin. These results suggested that the swpAB system can alter gene expression patterns and change bacterial physiological activity without affecting bacterial growth.
Actual pressure generated by various suction technique and suctioning liquid weight through endoscopic ultrasound‐guided aspiration needles
Authors: Sheng Li Ping , Lin Rong , Tao Xu , Guo Xian Wen , Han Chao Qun , Nie Chi , Zhang Kun , Ding Zhen 
Published: January 2023

ObjectivesSuction pressure is one of the most important factors influencing the amount of tissue obtained during endoscopic ultrasound‐guided fine‐needle aspiration/biopsy (EUS‐FNA/FNB). In this study we aimed to elucidate actual suction pressure generated by various suction methods and the weight of suctioning liquid.MethodsDifferent types of fine needles and suction techniques were used, including the slow pull technique (SPT), dry suction technique (DST), wet suction technique (WST), neutralizing negative pressure technique (NNPT), and residual negative pressure technique (RNPT). Actual suction pressure was measured and the amount of suctioning liquid was weighed.ResultsActual suction pressure and weight of the suctioning liquid were lower using SPT than using DST, while they were higher when using WST compared with those using DST. In general, the actual suction pressure increased and the weight of suctioning liquid decreased as the diameter of the FNA needles decreased. While weight of the suctioning liquid using FNB needles was significantly larger than that using FNA needles. In general, the actual suction pressure generated using RNPT was larger than that using NNPT.ConclusionsWST is superior to SPT and DST in terms of actual suction pressure and weight of suctioning liquid. Diameter of the FNA needle was an important factor that may affect the actual suction pressure and weight of suctioning liquid. FNB needles are superior to FNA needles when it comes to the weight of suctioning liquid. Actual suction pressure obtained by novel suction methods (NNPT and RNPT) may provide a basis for future research.
Derivation of the multiply‐branched ergot alkaloid pathway of fungi
Authors: Panaccione Daniel G. 
Published: January 2023

AbstractErgot alkaloids are a large family of fungal specialized metabolites that are important as toxins in agriculture and as the foundation of powerful pharmaceuticals. Fungi from several lineages and diverse ecological niches produce ergot alkaloids from at least one of several branches of the ergot alkaloid pathway. The biochemical and genetic bases for the different branches have been established and are summarized briefly herein. Several pathway branches overlap among fungal lineages and ecological niches, indicating activities of ergot alkaloids benefit fungi in different environments and conditions. Understanding the functions of the multiple genes in each branch of the pathway allows researchers to parse the abundant genomic sequence data available in public databases in order to assess the ergot alkaloid biosynthesis capacity of previously unexplored fungi. Moreover, the characterization of the genes involved in the various branches provides opportunities and resources for the biotechnological manipulation of ergot alkaloids for experimentation and pharmaceutical development.
First‐in‐human application of double‐stranded RNA bacteriophage in the treatment of pulmonary Pseudomonas aeruginosa infection
Authors: Li Linlin , Zhong Qiu , Zhao Yunze , Bao Juan , Liu Bing , Zhong Zhuojun , Wang Jing , Yang Lan , Zhang Tingting , Cheng Mengjun , Wu Nannan , Zhu Tongyu , Le Shuai 
Published: January 2023

AbstractA double‐stranded RNA (dsRNA) phage phiYY is able to kill a pyomelanin‐producing Pseudomonas aeruginosa strain, which was isolated from a 40‐year‐old man with interstitial lung disease (ILD) and chronic lung infection. Phage therapy was used as a last resort for this patient. The three‐course nebulized phiYY treatment was used to reduce the bacterial burden and clinical symptoms of the patient. Recurrences of P. aeruginosa infections were observed 1–3 days post phage therapy. The recurrent isolates exhibited distinct antibiotic‐susceptibility profiles compared with the original strain yet were still susceptible to phiYY. This assay represents the application of dsRNA phage in the treatment of chronic lung infection, albeit the safety and efficacy of the dsRNA phage require further assessment.
C‐PLAN index as a prognostic factor for patients with previously untreated advanced non‐small cell lung cancer who received combination immunotherapy: A multicenter retrospective study
Authors: Sonehara Kei , Ozawa Ryota , Hama Mineyuki , Nozawa Shuhei , Agatsuma Toshihiko , Nishie Kenichi , Kato Akane , Matsuo Akemi , Araki Taisuke , Komatsu Masamichi , Tateishi Kazunari , Hanaoka Masayuki 
Published: January 2023

AbstractBackgroundCombination immunotherapy (immune checkpoint inhibitors and cytotoxic anticancer agents) is widely used as first‐line treatment for advanced non‐small cell lung cancer (NSCLC). However, the therapeutic effect of combination immunotherapy has not been fully investigated. C‐reactive protein, performance status, lactate dehydrogenase, albumin, and derived neutrophil‐to‐lymphocyte ratio (C‐PLAN) are useful biomarkers for predicting the prognosis of NSCLC; however, there are no reports examining the C‐PLAN index, which combines these five factors in a single prognostic factor.MethodsWe retrospectively collected data from 178 patients with previously untreated advanced NSCLC who received combination immunotherapy at multicenter institutions in Nagano Prefecture between December 2018 and April 2022. We investigated the utility of the C‐PLAN index as a prognostic factor using Cox regression analysis and correlated it with survival.ResultsThe good and poor C‐PLAN index groups included 85 and 93 patients, respectively. The good C‐PLAN index group had a longer median progression‐free survival (PFS) (10.7 vs. 6.0 months; p = 0.022) and overall survival (OS) (25.3 vs. 16.5 months; p = 0.003) than the poor C‐PLAN index group. The C‐PLAN index was an independent favorable prognostic factor that correlated with PFS and OS in multivariate analysis. The good C‐PLAN index group had a higher proportion of never‐smokers (16.5 vs. 4.3%; p = 0.007) and stage III disease/postoperative recurrence (32.9 vs. 15.1%; p = 0.005) than the poor C‐PLAN index group.ConclusionThe C‐PLAN index is a useful prognostic factor for patients with previously untreated advanced NSCLC undergoing combination immunotherapy.
Fishers who don't fish
Authors: Thomas Eric H. 
Published: January 2023

AbstractIn 2018, an unprecedented red tide prompted Chile's Ministry of Health to close fisheries throughout the country's southern Aysén Region. The disaster heightened the precarity of “paper fishers,” or those who seldom fish but deftly navigate Chile's neoliberal fisheries management system. Amid the crisis, these fishers performed valuable distributive labor. They connected benefits from transferable fishing quotas to community‐based networks, persuaded officials to recognize additional claimants, and redistributed cash in their communities. This enabled fishers to access public funds when fishing was impossible and strengthened community solidarity in the face of precarity. Yet it also required that claims for financial compensation be legible to state officials, and it prevented political actions that would have disrupted the state‐backed aquaculture industry, despite the latter's contribution to the red tide. Thus, neoliberal distributive programs that depend on the commodification of nature simultaneously benefit rural communities in crisis and facilitate the displacement of beneficiaries.
Refusing aid
Authors: O'Sullivan Sarah 
Published: January 2023

Abstract“Aid dependency” has long been a concern among development organizations, because it supposedly discourages the entrepreneurial spirit and thus hinders economic development. But what happens when beneficiaries refuse aid? In this article, I offer an ethnographic account of aid refusal in postconflict northern Uganda. There, members of savings and loan associations negotiate debts and investments through Acholi ethics ofripe, or “making life experiences together.” In doing so, they demonstrate that their refusals are not disavowals of development. Rather, they are refusals of development hierarchies and of the financialization of development, both of which risk obstructing Acholi ethics of interdependence. By analyzingripeand the ways that association members negotiate the ethics of receiving aid, this article offers a counterpoint to dominant, pathologizing discourses of African dependency, corruption, and development—discourses predicated on Western, neoliberal valuations of work and community. In short, this article calls into question the assumption that economic growth is always the sine qua non of development.
Venoarterial extracorporeal membrane oxygenation improves survival in a rat model of acute myocardial infarction
Authors: Wei Shilin , Cheng Xingdong , Li Jian , Zhai Kerong , Huang Jian , Wang Shixiong , Li Yongnan , Liu Debin 
Published: January 2023

AbstractBackgroundVenoarterial extracorporeal membrane oxygenation (VA‐ECMO) has been widely used in high‐risk acute myocardial infarction (AMI) patients with promising outcomes. However, the underlying molecular mechanisms remain unknown and a VA‐ECMO animal model has not yet been established. The purpose of this study was to establish a VA‐ECMO model in AMI rats and evaluate long‐term cardiac function.MethodsWe first established AMI in 20 Sprague–Dawley (SD) rats by ligating the left anterior descending coronary artery, while five rats underwent a thoracotomy to form the sham group. VA‐ECMO was established after 30mins of AMI in 10 rats through the right jugular vein for venous drainage and right femoral artery for arterial infusion. Arterial blood pressure was monitored using a catheter in the left femoral artery, blood gas parameters were measured using a blood gas analyzer, while myocardial enzymes were detected using an ELISA Kit. Cardiac function was assessed through echocardiography on day 15. Masson staining and Western Blot were used for evaluating myocardial fibrosis, while histological injury was evaluated using hematoxylin and eosin staining.ResultsVA‐ECMO support stabilized blood pressure, decreased the levels of myocardial enzymes including cTnI, cTnT, CK‐MB, and was associated with a higher survival rate. In the long term, the VA‐ECMO group showed improved cardiac function, significantly increased EF and FS but significantly decreased EDV and ESV compared to the AMI group. Furthermore, VA‐ECMO significantly alleviated pathological damage and myocardial fibrosis.ConclusionWe established an economical, reliable, and reproducible VA‐ECMO animal model in AMI rats, and demonstrated that VA‐ECMO support prevents deteriorated cardiac function.
Australian perspective on engaging with South Korea in the Indo‐Pacific
Authors: Kim Jiye , Raswant Arpit 
Published: January 2023

AbstractHow do the US allies engage with other actors in the US‐led Indo‐Pacific security order? This article examines this question in the case of Australia. We argue that the regional strategic network is a key consideration for Australia to facilitate its interaction with a target country in the Indo‐Pacific. This article analyzes Australia's approach toward South Korea as an example demonstrating the significance of the regional strategic network in shaping Australia's diplomacy. It does so by addressing the following three questions. First, what is Australia's vision for the Indo‐Pacific? Second, how does Australia perceive South Korea's role in the Indo‐Pacific? Third, how does Australia's Indo‐Pacific vision find the relevance of South Korea for Australia's security interests? The article elucidates that Australia's view on South Korea's place in the Indo‐Pacific security network influences Australia's interaction with South Korea and consequently plays an integral part in the US‐led regional security order‐building process.
Treating bipolar depression with esketamine: Safety and effectiveness data from a naturalistic multicentric study on esketamine in bipolar versus unipolar treatment‐resistant depression
Authors: Martinotti Giovanni , Dell'Osso Bernardo , Di Lorenzo Giorgio , Maina Giuseppe , Bertolino Alessandro , Clerici Massimo , Barlati Stefano , Rosso Gianluca , Di Nicola Marco , Marcatili Matteo , d'Andrea Giacomo , Cavallotto Clara , Chiappini Stefania , De Filippis Sergio , Nicolò Giuseppe , De Fazio Pasquale , Andriola Ileana , Zanardi Raffaella , Nucifora Domenica , Di Mauro Stefania , Bassetti Roberta , Pettorruso Mauro , McIntyre Roger S. , Sensi Stefano L. , di Giannantonio Massimo , Vita Antonio ,   the REAL‐ESK Study Group
Published: January 2023

AbstractBackgroundBipolar depression accounts for most of the disease duration in type I and type II bipolar disorder (BD), with few treatment options, often poorly tolerated. Many individuals do not respond to first‐line therapeutic options, resulting in treatment‐resistant bipolar depression (B‐TRD). Esketamine, the S‐enantiomer of ketamine, has recently been approved for treatment‐resistant depression (TRD), but no data are available on its use in B‐TRD.ObjectivesTo compare the efficacy of esketamine in two samples of unipolar and bipolar TRD, providing preliminary indications of its effectiveness in B‐TRD. Secondary outcomes included the evaluation of the safety and tolerability of esketamine in B‐TRD, focusing on the average risk of an affective switch.MethodsThirty‐five B‐TRD subjects treated with esketamine nasal spray were enrolled and compared with 35 TRD patients. Anamnestic data and psychometric assessments (Montgomery‐Asberg Depression Rating Scale/MADRS, Hamilton‐depression scale/HAM‐D, Hamilton‐anxiety scale/HAM‐A) were collected at baseline (T0), at one month (T1), and three months (T2) follow up.ResultsA significant reduction in depressive symptoms was found at T1 and T2 compared to T0, with no significant differences in response or remission rates between subjects with B‐TRD and TRD. Esketamine showed a greater anxiolytic action in subjects with B‐TRD than in those with TRD. Improvement in depressive symptoms was not associated with treatment‐emergent affective switch.ConclusionsOur results supported the effectiveness and tolerability of esketamine in a real‐world population of subjects with B‐TRD. The low risk of manic switch in B‐TRD patients confirmed the safety of this treatment.
Multilevel SEM with random slopes in discrete data using the pairwise maximum likelihood
Authors: Barendse Maria T. , Rosseel Yves 
Published: January 2023

AbstractPairwise maximum likelihood (PML) estimation is a promising method for multilevel models with discrete responses. Multilevel models take into account that units within a cluster tend to be more alike than units from different clusters. The pairwise likelihood is then obtained as the product of bivariate likelihoods for all within‐cluster pairs of units and items. In this study, we investigate the PML estimation method with computationally intensive multilevel random intercept and random slope structural equation models (SEM) in discrete data. In pursuing this, we first reconsidered the general ‘wide format’ (WF) approach for SEM models and then extend the WF approach with random slopes. In a small simulation study we the determine accuracy and efficiency of the PML estimation method by varying the sample size (250, 500, 1000, 2000), response scales (two‐point, four‐point), and data‐generating model (mediation model with three random slopes, factor model with one and two random slopes). Overall, results show that the PML estimation method is capable of estimating computationally intensive random intercept and random slopes multilevel models in the SEM framework with discrete data and many (six or more) latent variables with satisfactory accuracy and efficiency. However, the condition with 250 clusters combined with a two‐point response scale shows more bias.