bluuebunny/crossref_metadata_2025_split huggingface dataset:
Strukturierte ABEV-Übungen zur Behandlung vestibulärer Funktionsstörungen
Authors: Zenner Benedikt P. , Schmitz Daniel , Zenner Hans-Peter , Wirth Markus 
Published: September 2023

Zusammenfassung
Einführung Die klinische Standardbehandlung des vestibulären Schwindels umfasst neben Medikamenten vor allem physikalische Therapie in Form von regelmäßigen Übungen. Vertidisan ist eine geplante digitale Gesundheitsanwendung (DiGA) zur strukturierten Schwindeltherapie. Ihr Inhalt ist multimodal und besteht unter anderem aus adaptiven Gleichgewichts-/Augenbewegungs- und visuellen Stimulationsübungen (Adaptive Balance and Eye Movements and Visual Stimulation, ABEV), von denen erwartet wird, dass sie durch neuronales Lernen eine antivertiginöse Wirkung haben.
Methoden Es wurde eine Kohortenstudie mit 104 Patienten mit intraindividueller Kontrolle durchgeführt, um die klinische Wirksamkeit von 16 ABEV-Übungen für die Behandlung von peripheren Vestibulopathien isoliert zu untersuchen, wie sie auch in der geplanten DiGA Vertidisan zum Einsatz kommen. Unter Verwendung der Kurzversion vertigo symptom scale short form1 vertigo and related symptoms (VSS-sf1-VER) der schwindelspezifischen und validierten VSS-Ratingskala (Vertigo Symptom Scale) als primäre Ergebnisvariable wurden die Schwindelwerte vor der Therapie (Zeitpunkt T0) mit den entsprechenden Daten am Ende eines Zeitraums von 12–16 Wochen (Zeitpunkt T1) verglichen.
Ergebnisse Von n=104 Patienten standen vollständige Datensätze zu T0 und T1 zur Verfügung. Der durchschnittliche VSS-sf1-V-Score verringerte sich von 3,80 (Median 4, Standardabweichung (SD) 0,47) auf 0,92 (Median 1, SD 1,19) von T0 bis T1 (Woche 12–16). Das Ergebnis ist statistisch signifikant (p=0,001) und weist eine hohe klinische Effektstärke auf.
Schlussfolgerung Zusammenfassend ergibt die Analyse des Schwindel-Scores eine statistisch und klinisch signifikante Verringerung des Schwindels durch die Anwendung der 16 ABEV-Leitübungen.
Association Between the XRCC1, GSTM1, and GSTT1 Polymorphisms in
Model of Thyroid Cancer: A Meta-Analysis
Authors: Yang Wenhan , Liu Wanyu , Zhu Lei , Lin Yaqi , Meng Zilu , Wang Yudong 
Published: September 2023

AbstractThyroid cancer is the most common malignant tumor of the endocrine system, and
its incidence is increasing worldwide each year. This study aimed to explore the
association between XRCC1, GSTM1, and GSTT1 polymorphisms in the model of
thyroid cancer. The experiment was conducted by searching PubMed, Embase, and
Web of Science, with the last search performed in March 2022. A total of 12
studies were included in this meta-analysis, with sample sizes ranging from 211
to 1124. The proportion of XRCC1 polymorphisms (rs25489, GG) in thyroid cancer
was slightly lower than that of the normal control group, but the difference was
not statistically significant (Mean difference=1.13, 95% CI:
0.99–1.28, p=0.08). The proportion of XRCC1 polymorphisms
(rs25489, GA) in thyroid cancer was significantly lower than that of the normal
control group (Mean difference=1.32, 95% CI: 1.16–1.52,
p<0.00001). The proportion of XRCC1 polymorphisms (rs25489, AA) in
thyroid cancer was slightly lower than that of the normal control group, but
again, the difference was not statistically significant (Mean
difference=0.78, 95% CI: 0.61–1.01, p=0.06).
Similarly, the proportion of XRCC1 polymorphisms (rs25487, GG) and (rs25487, GA)
in thyroid cancer was lower than that of the normal control group, but the
differences were not statistically significant (p=0.22 and
p=0.49, respectively). In conclusion, this study found that the
proportion of XRCC1 polymorphisms (rs25489, AA) in thyroid cancer was lower than
that of the normal control group.
Anfallsklassifikation
Authors: Noachtar Soheyl , Baumgartner Christoph 
Published: September 2023

ZusammenfassungDie Fortschritte in Diagnostik der Epilepsien machten es erforderlich die 1981
publizierte Anfallsklassifikation der Internationalen Liga gegen Epilepsie
(ILAE) zu überarbeiten. Nach jahrelanger Diskussion wurde von der ILAE
2017 eine neue Anfallsklassifikation vorgestellt, die ebenfalls elektroklinisch
vorgeht, d. h. die Anfallsemiologie und Befunde technischer
Zusatzuntersuchungen einbezieht. Die Begrifflichkeit einfach-fokaler und komplex
fokaler Anfälle wurde verlassen und die Betonung auf den Beginn der
Anfälle gesetzt.Demgegenüber steht eine Semiologische Anfallsklassifikation, die
epileptische Anfälle ausschließlich auf der Grundlage der
Anfallssemiologie klassifiziert und sich alter Begriffe wie z. B. Auren
bedient. Beide Vorgehensweisen zur Anfallsklassifikation werden
erläutert.
Additive-Free Copper-Catalyzed Benzylic C(sp3)–H Carbamation: Simple Preparation of Primary Benzylic Amines
Authors: Bakhoda Abolghasem , Schmidt William 
Published: September 2023

AbstractA simple and practical method for the synthesis of primary alkylamines by direct functionalization of hydrocarbons is described. The N-Boc-protected alkylamines are readily prepared from tert-butyl (trimethylsilyl)carbamate and N-fluorobenzenesulfonimide in the presence of a Cu(I) catalyst at low catalyst loadings. Advantageously, this process proceeds free of any additive such as auxiliary bases/acids, requires only one equivalent of the substrate, and does not require ligand synthesis. This operationally simple C–H carbamation method shows high site selectivity and good functional-group tolerance, and uses a commercially available Cu precatalyst and oxidant to furnish N-Boc protected alkylamines in yields of 16–83%. The products can be simply deprotected under mild acidic conditions to generate primary benzylic amines. This practical method was subsequently used for the synthesis of the active pharmaceutical ingredients cinacalcet and sertraline.
Reaction of Highly Volatile Organic Compounds with Organolithium Species in Flow Microreactor
Authors: Nagaki Aiichiro , Muta Kensuke , Okamoto Kazuhiro 
Published: September 2023

AbstractHighly volatile organic compounds (VOCs) with boiling points (bp) around or below room temperature are generally difficult to manipulate precisely in liquid-phase organic reactions although they offer significant atom-economic advantages. We have developed a novel approach using a jacketed syringe pump to enable the formylation of organolithium species in a continuous-flow system under ambient pressure. Methyl formate (bp 32 °C) worked as a formylating agent and was successfully delivered to the continuous operation for over 30 minutes in our microflow system. This methodology was successfully expanded to the application of acetaldehyde (bp 21 °C) and heptafluoropropyl bromide (bp 12 °C).
Connections between family violence and violence in the public sphere in Afghanistan
Authors: Orang Mina , Choi Fiona , Krausz R. Michael , Hewad Atal , Suen Janet , Jang Kerry , Missmahl Inge 
Published: September 2023

AbstractAfghanistan has endured over four decades of violence in the public sphere, such as war and suicide attacks. To effectively provide psychosocial counseling using a psychodynamic approach in Afghanistan, it is crucial to recognize the potential connection between ongoing public violence and high rates of family violence. In 2019, we conducted a study to explore the relationship between public violence and family violence among Kabul residents, including those seeking counseling and those who were not. Our cross-sectional mixed methods survey recruited 299 participants from a psychosocial counseling service as well as community members who were not receiving the service. The findings revealed a significant positive correlation between experiences of public violence and family violence. Both clients and non-clients reported experiencing high levels of violence, which led to impairments in daily functioning and increased suicidality. Additionally, a thematic analysis of open-ended questions indicated changes in attitudes resulting from exposure to violence, including feelings of helplessness and hopelessness both in and out of the home. We conclude that applying a psychodynamic approach to psychosocial counseling in Afghanistan requires awareness of the positive correlation between public violence and family violence in a society that has been exposed to violence in the public sphere for over forty years. Mental health care needs to contribute towards breaking cycles of violence by empowering clients to take control of their lives and become agents of change within their families and communities.
Localisation of Composite capital designs in modern Jiangsu, China, based on formal and social analysis
Authors: Wang Xinyi , Guo Weimin , Yang Zhi , Li Xiaoya , Zhang Bowen 
Published: September 2023

AbstractThe evolution of architectural forms is a significant field of study in modern hybrids of Chinese and foreign architecture. It involves exploring the integration of foreign buildings and their constituent elements into traditional Chinese local culture. The Composite capital is a key component in Western architecture. Research indicates that from the 1920s to 1930s, Composite capital designs in foreign architectural structures within the Jiangsu region exhibited period-specific evolutionary characteristics and variations among different cities. Therefore, the localisation of Composite capitals in Jiangsu is a gradual process. This paper proposes a research methodology combining formal analysis and social analysis to investigate the localisation of Composite capitals in Jiangsu during the modern period. The study yields two main conclusions: (1) Within the same social environment, there are common patterns in the localisation of Composite capital designs among different historical periods, reflecting shared developmental trends influenced by local traditional culture. (2) Different cities in the Jiangsu region, characterised by distinct social environments, exhibit unique patterns in the localisation of Composite capital designs, reflecting regional diversity and providing more possibilities for localisation. This paper investigates the localisation of Composite capital designs in modern Jiangsu and explores the factors that influence the form and value of capital designs, providing a systematic reference for the study of regional architectural localisation in the modern period in China.
The TU Wien Turbulent Water Channel: Flow control loop and three-dimensional reconstruction of anisotropic particle dynamics
Authors: Giurgiu Vlad , Caridi Giuseppe Carlo Alp , Alipour Mobin , De Paoli Marco , Soldati Alfredo 
Published: September 2023

A horizontal water channel facility was built to study particle dynamics in a turbulent flow. The channel is sufficiently long to produce fully developed turbulence at the test section, and the width-to-height ratio is sufficiently large to avoid the sidewall effect for a large proportion of the cross-section. The system was designed to study the dynamics of complex-shaped particles in wall-bounded turbulence, the characteristics of which can be finely controlled. A maximum bulk velocity of up to 0.8 m s−1 can be achieved, corresponding to a bulk Reynolds number of up to 7 × 104 (shear Reynolds number ≈1580), and flow parameters can be controlled within ±0.1%. The transparent channel design and aluminum structures allow easy optical access, which enables multiple laser and camera arrangements. With the current optical setup, a measurement volume of up to 54 × 14 × 54 mm3 can be imaged and reconstructed with six cameras from the top, bottom, and sides of the channel. Finally, the in-house developed reconstruction and tracking procedure allows us to measure the full motion of complex objects (i.e., shape reconstruction, translational, and rotational motions), and in this instance, it is applied to the case of microscopic, non-isotropic polyamide fibers.
High-order geometric integrators for the variational Gaussian approximation
Authors: Moghaddasi Fereidani Roya , Vaníček Jiří J. L. 
Published: September 2023

Among the single-trajectory Gaussian-based methods for solving the time-dependent Schrödinger equation, the variational Gaussian approximation is the most accurate one. In contrast to Heller’s original thawed Gaussian approximation, it is symplectic, conserves energy exactly, and may partially account for tunneling. However, the variational method is also much more expensive. To improve its efficiency, we symmetrically compose the second-order symplectic integrator of Faou and Lubich and obtain geometric integrators that can achieve an arbitrary even order of convergence in the time step. We demonstrate that the high-order integrators can speed up convergence drastically compared to the second-order algorithm and, in contrast to the popular fourth-order Runge–Kutta method, are time-reversible and conserve the norm and the symplectic structure exactly, regardless of the time step. To show that the method is not restricted to low-dimensional systems, we perform most of the analysis on a non-separable twenty-dimensional model of coupled Morse oscillators. We also show that the variational method may capture tunneling and, in general, improves accuracy over the non-variational thawed Gaussian approximation.
Testing Lorentz symmetry with space-based gravitational-wave detectors
Authors: Qin Cheng-Gang , Ke Jun , Li Qin , Chen Ya-Fen , Luo Jie , Tan Yu-Jie , Shao Cheng-Gang 
Published: September 2023

Abstract
Lorentz symmetry (LS), one of the most fundamental physical symmetries, has been extensively studied in the context of quantum gravity and unification theories. Many of these theories predict a LS violation, which could arise from the discreteness of spacetime, or extra dimensions. Standard-model extension (SME) is an effective field theory to describe Lorentz violation whose effects can be explored using precision instruments such as atomic clocks and gravitational-wave (GW) detectors. Considering the pure-gravity sector and matter-gravity coupling sector in the SME, we studied the leading Lorentz-violating modifications to the time delay of light and the relativistic frequency shift of the clock in the space-based GW detectors. We found that the six data streams from the GW mission can construct various combinations of measurement signals, such as single-arm round-trip path, interference path, triangular round-trip path, etc. These measurements are sensitive to the different combinations of SME coefficients and provide novel linear combinations of SME coefficients different from previous studies. Based on the orbits of TianQin, LISA, and Taiji missions, we calculated the response of Lorentz-violating effects on the combinations of the measurement signal data streams. Our results allow us to estimate the sensitivities for SME coefficients: 10−6 for the gravity sector coefficient

s
ˉ

T
T

, 10−6 for matter-gravity coupling coefficients

(

a
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eff

(
e
+
p
)

)

T

and

c
ˉ

T
T

(
e
+
p
)

, and 10−5 for

(

a
ˉ

eff

n

)

T

and

c
ˉ

T
T

n

.
Inverse radiative transfer with goal-oriented hp-adaptive mesh refinement: adaptive-mesh inversion
Authors: Du Shukai , Stechmann Samuel N 
Published: September 2023

Abstract
The inverse problem for radiative transfer is important in many applications, such as optical tomography and remote sensing. Major challenges include large memory requirements and computational expense, which arise from high-dimensionality and the need for iterations in solving the inverse problem. Here, to alleviate these issues, we propose adaptive-mesh inversion: a goal-oriented hp-adaptive mesh refinement method for solving inverse radiative transfer problems. One novel aspect here is that the two optimizations (one for inversion, and one for mesh adaptivity) are treated simultaneously and blended together. By exploiting the connection between duality-based mesh adaptivity and adjoint-based inversion techniques, we propose a goal-oriented error estimator, which is cheap to compute, and can efficiently guide the mesh-refinement to numerically solve the inverse problem. We use discontinuous Galerkin spectral element methods to discretize the forward and the adjoint problems. Then, based on the goal-oriented error estimator, we propose an hp-adaptive algorithm to refine the meshes. Numerical experiments are presented at the end and show convergence speed-up and reduced memory occupation by the goal-oriented mesh adaptive method.
Integrated navigation model based on TDCP constrained algorithm
Authors: Liu Yanlong , Li Zengke , Ning Yipeng 
Published: September 2023

Abstract
The velocity information estimated by the global navigation satellite system (GNSS) receiver is an important element for the dynamic alignment of the inertial navigation system, and it is of great significance to analyze it deeply and meticulously. A variety of GNSS velocity measurement models show different characteristics in a changeable environment, and this status quo is bound to break the monotonous situation in which the Doppler model is widely used. In this regard, this paper applies different GNSS velocity measurement models to strap-down interial navigation system (SINS) dynamic alignment and continuous observation. In addition, aiming at the shortcomings of the traditional time-differenced carrier phase (TDCP) algorithm, an optimization method is deduced from the formula level, and two effective constraint algorithms are given. Then, according to the vehicle test results, comprehensively compare the integrated navigation performance of various speed measurement models, and analyze the improvement effect of the proposed TDCP algorithm. This paper provides a summary for the comprehensive study of GNSS velocity measurement model and the application of optimized carrier phase to integrated navigation, which has certain practical value.
Room-temperature-processed synaptic a-IGZO TFT with high-k HfLaO gate dielectric as neuromodulator
Authors: Huang An , Ma Yuan Xiao , Li Jia Cheng , Dai De , Yang Hui Xia , Liu Zi Chun , Zhang De Cheng , Yang Han , Huang Yuan , Zhang Yi Yun , Li Xiao Ran , Wang Ye Liang , Lai Pui To 
Published: September 2023

Abstract
In this work, room-temperature-processed amorphous InGaZnO (a-IGZO) thin-film transistors (TFTs) have been fabricated with high-k HfLaO as gate dielectric for synaptic devices. By raising the indium content in the a-IGZO film via co-sputtering and treating the HfLaO gate dielectric in an Ar plasma, the TFT with In1.0Ga3.0Zn0.4O2.1 presents excellent electrical characteristics: a high intrinsic carrier mobility of 45.8 cm2 V−1·s−1, a small threshold voltage of 1.93 V, a small hysteresis of −0.015 V, and a small subthreshold swing (SS) of 0.21 V dec−1. Although the oxygen vacancies in the In1.0Ga3.0Zn0.4O2.1 TFT are increased to produce a high carrier mobility, memristive behaviors are hardly observed under zero gate bias due to their occupied states. Various conductance modulations and synaptic plasticities are achieved under a 2-V drain spiking voltage and a small gate bias of 1 V due to migration of oxygen ions and emptying/detrapping of oxygen vacancies in the In1.0Ga3.0Zn0.4O2.1 film, resulting in a concurrent emulation of neurotransmitter and neuromodulator through exploiting the native three-terminal structure of the TFT.
Theoretical analysis of conduction-cooled current lead for superconducting magnet
Authors: Zong Zhanguo , Shimizu Hirotaka 
Published: September 2023

Abstract
CCCL is a typical CL type to energise SC magnets from room to cryogenic temperatures (<100 K) for its simplicity and reliability, but causes a relatively large heat leak (∼50 W kA−1 from 300 K) compared to the heat leak (∼1.0 W kA−1 from 300 K to liquid helium) of VCCLs, which necessitates a comprehensive understanding of designers and users. However, systematic studies on CCCLs are still lacking up to now. This study starts from the differential equation governing heat conduction and generation in CCCLs and firstly derives a completely exact theoretical solution by adopting the WFL law for thermal conductivity and electrical resistivity with temperature dependence. The solution facilitates the CCCL design optimisation to achieve the minimum heat leak, which is determined only by the temperature range but independent of both materials and geometrical parameters. Practical optimum designs are concerned with material properties and approached by calculating a shape factor to determine the conductor length and cross-sectional area, which is detailed and illustrated in this paper. Furthermore, the practical behaviours at low and excess currents can also be mathematically deduced, and the corresponding heat leaks are found to rely on materials but not on geometrical parameters. This paper also describes the agreements between the theoretical analysis and the numerical simulation and comparison with material properties of the non-WFL law.
Thermal and durability characteristics of optimized green concrete developed using slag powder and pond ash
Authors: Maheswaran Jeyaprakash , Chellapandian Maheswaran , Arunachelam Nakarajan , Hari Manikandan Naga Theera 
Published: September 2023

Abstract
Due to the vast development in the infrastructure section, the production of cement-based concrete is a major driving source for the increased global warming and extensive deployment of natural resources such as river sand. To reduce and mitigate these adverse effects, industrial by-products can be effectively used either in partial or complete levels to replace conventional materials such as cement, river sand, etc without compromising the strength and durability characteristics of concrete. This research work focuses on the experimental investigation of the thermal properties, strength, durability and microstructure analysis of optimized green concrete with pond ash and ground granulated blast-furnace slag (GGBS). The novelty of the proposed work lies in the investigation of the thermal and durability characteristics of sustainable green concrete with GGBS and pond ash as a partial replacement for cement and fine aggregate respectively. An optimum mix ratio obtained from the material characterization of 16 trail mixes was tested for mechanical properties, durability and thermal characterization. Moreover, the microstructure analysis of the optimized mix was performed using Scanning Electron Microscope (SEM) to overview the chemical constituents, bonding of molecules at the interfacial transition zone (ITZ), the effect of elevated temperature, etc Results from the trail mixes revealed that the replacement of 30% GGBS and 20% pond ash increased the compressive strength by 8% at 28 days of curing when compared to the control mix. In addition, a detailed multilinear regression analysis was performed and a new equation was proposed to determine the compressive strength of concrete with GGBS and pond ash. The predictions obtained from the proposed equation showed a good match with the benchmark experiments.