bluuebunny/crossref_metadata_2025_split huggingface dataset:
All-biomass Cellulose/Casein Adsorbent Fabricated via the "Green Solvent System" of Ionic Liquid for the Efficient Removal of Cu(II), Cd(II) and Pb(II)
Authors: Qian Liwei , Chen Haonan , Zhang Sufeng , Yang Yuxuan , Zhang Lulu , Yang Miaoxiu , Song Wenqi , Nica Valentin 
Published: April 2023

Abstract
The development of all-biomass adsorbents capable of effectively removing metal ions from wastewater is urgently required in accordance with the trend toward sustainable development and the requirements for environmental protection. In this study, a strategy was proposed to achieve convenient preparation of cellulose/casein composite hydrogel adsorbents (CE/CA) via adopting ionic liquid (IL) as a corporate solvent. The favorable solubility of IL and its negligible vapor pressure enabled the CE/CA to obtain a honeycomb-shaped surface structure while recycling IL in the material preparation process through simple vacuum evaporation technology. Consequently, the CE/CA exhibited a rapid adsorption rate (≤ 90 min) and extremely high adsorption capacities (≥ 230 mg g-1) toward Cu(II), Cd(II), and Pb(II), respectively. As indicated by the results of adsorption model fitting and XPS analysis, the binding of the CE/CA to the metal ions was primarily achieved through chemisorption and monolayer adsorption, and both cellulose and casein contributed to the high adsorption capacity of adsorbent through chelation. Lastly, the metal ions were removed at different concentrations (≥ 2 mg L-1) in simulated wastewater using the CE/CA. The results confirm that the aqueous solution treated with adsorbent can meet the safe drinking level standard (US EPA).
Development and validation of a tool to assess researchers’ knowledge of human subjects’ rights and their attitudes toward research ethics education in Saudi Arabia
Authors: Al-Madaney May M. , Fässler Margrit 
Published: April 2023

Abstract
Background
Researchers must adhere to ethical and scientific standards in their research involving human subjects; therefore, their knowledge of human subjects’ rights is essential. A tool to measure the extent of this knowledge is necessary to ensure that studies with participants are conducted ethically and to enhance research integrity. Currently, no validated instrument is available for such an assessment. Therefore, the primary purpose of this study is to develop a reliable and valid instrument to assess researchers’ knowledge of human subjects’ rights in clinical settings, as well as a reliable and valid measure of their attitudes toward clinical research ethics education in Saudi Arabia.
Methods
The current study involves the development of a questionnaire about the rights of human subjects in research and the researchers’ attitudes toward research ethics education. The content was developed based on an extensive review of research ethics guidelines. A panel of experts tested the questionnaire for face validity (n = 5) and content validity (n = 8). The reliability of the questionnaire was established by a split-half reliability coefficient and item analysis among a sample (n = 301) of clinical researchers.
Results
Face validity demonstrated that the questionnaire was quick to complete and easy to answer. The global content validity indices (S-CVIs) were greater than 0.78 for all questionnaire sections; the split-half reliability coefficient was 0.755 for knowledge items; Cronbach's alpha was 0.77 for researchers' attitudes, showing good internal consistency. The difficulty index ranged from 12.0–98.7% for all knowledge items. Most questions were at an acceptable level of reliability and discrimination criteria. The final version of the questionnaire contained 89 items, distributed as 15 questions on demographic and professional characteristics, 64 questions items on knowledge, and 10 items on attitudes.
Conclusions
The questionnaire is a valid and reliable tool to assess biomedical researchers’ knowledge of human subjects’ rights and their attitudes toward research ethics education. This instrument could help address the gap in researchers’ knowledge of the rights and facilitate the development of educational intervention programs to set appropriate learning objectives.
Spectrum of Presentation, Diagnosis, and Clinical Outcome of Central Nervous System Tuberculosis: A case series in Bangabandhu Sheikh Mujib Medical University
Authors: Siddik Sahariar Hossain , Ahmed Khandakar Rashed , Hasan S M Shiam , Tasnim Zarin , Zaman Asad , Yasmin Roksana , Sarwar M Golam , Monsur Mahin , Ahmed Foysal , Sultana Rezvey , Sumaiya Towhida Sultana 
Published: April 2023

Abstract
Introduction: Tuberculosis (TB) is highly prevalent in Bangladesh. The affection of the central nervous system(CNS) is one of the most dangerous manifestations of extrapulmonary tuberculosis. This may take the form of either tubercular meningitis (TBM), tuberculoma, or spinal arachnoiditis. CNS tuberculosis (CNS-TB) carries high morbidity and mortality among all forms of TB. The diagnosis is difficult and often delayed due to the varied and non-specific presentation. Aside from clinical indicators, cerebrospinal fluid (CSF) diagnostic indicators include mononuclear pleocytosis, low sugar levels, and high protein concentrations. It is possible to confirm Mycobacterium tuberculosis in CSF using staining, culture methods, and molecular analysis, but it is difficult. Advanced radiological imaging techniques can often be very helpful in making presumptive diagnoses, but they do not always yield confirm diagnoses.
Aim: In our case series, we aimed to highlight the spectrum of presentation of CNS tuberculosis, diagnostic challenges, and initial response to anti-TB drugs.
Material and Methods: We report a case series of six patients with CNS tuberculosis admitted to the neurology department between 2022 and 2023. Four of them were prospectively reviewed and two retrospectively. Data on presentation, diagnostic workup, and treatment were analyzed.
Result: We presented six cases of CNS TB from 2022 to 2023. Four cases among six had only TBM, two cases had concomitant intracranial tuberculoma and two cases had tuberculosis in the extracranial site. The most common presentation were fever, altered consciousness level, and constitutional symptoms. CSF study was done and revealed increased total protein in all six cases, lymphocytic pleocytosis in 66.67% of cases, a low sugar level in 50% of cases, and raised ADA level in 66.67% of cases. MTB was detected in a polymerase chain reaction (PCR) in one case and was none positive for AFB stain and culture. MRI with contrast showed meningeal enhancement in all six cases, hydrocephalus in 66.67% of cases, and infarction and tuberculoma in 33.33 % of cases. Brain biopsy for histopathological confirmation was not done. All of them had an anti-tubercular therapy and reported good clinical responses at 21-day-follow up.
Conclusion: CNS TB should be diagnosed primarily based on compatible clinical features, morphological findings on brain MRI, and CSF findings. In Bangladesh, CNS TB should always be considered an important differential diagnosis in patients with prolonged fever and headache, as well as altered consciousness level, and treatment should be initiated immediately on the basis of strong clinical suspicion, rather than waiting for laboratory confirmation.
Synovial sarcoma of Female Urethra: A case report and review of the literature
Authors: Cui Wei , Liao Yuanjian , Su Peng , Yang Hua , Zhang Neng 
Published: April 2023

Abstract
Synovial sarcoma (SS) is a rare malignant soft tissue sarcoma that originates from primitive mesenchymal cells with epithelial differentiation potential. It is most commonly found in the limbs and trunk，In the urinary system, it is mostly found in the kidneys. However, synovial sarcomas originating from the external urethra are extremely rare. Only one case of synovial sarcoma arising from the vulvar urethral orifice has been reported previously, and we report a second case of synovial sarcoma of the urethral orifice. This study reports a case of an elderly female patient with synovial sarcoma originating from the external urethral orifice. Urethral haemorrhage was noted after activity, with visible carnivorous haematuria. Physical examination revealed a vulvar tumour measuring approximately 3cmx4cm, Combined with the histopathological and immunohistochemical findings, synovial sarcoma was finally considered. In addition, this report reviews the literature from 1966 to the present. A total of 16 vulvar synovial sarcomas were identified and analyzed.
Elevated Respiratory Complications following Robotic-Assisted Lobectomy: A National Cohort Analysis of 26,140 Cases
Authors: Huang Ruijian , Xiao Yue , Jiang Feng , Chen Yanfei , Su Cunhua , Zhou Jifang 
Published: April 2023

Abstract

Background
The national use of robotic-assisted lobectomy is on the rise. Comparative data from the national contemporary retrospective cohort is lacking. The aim of this study was to estimate the risk of perioperative complication rate for patients who underwent video-assisted thoracoscopic (VATS), robotic-assisted lobectomy compared to open lobectomy.
Methods
Eligible admissions were identified from the hospital administrative data collected between January 1, 2015, and December 31, 2019, and identified lobectomy wherein VATS, robotic-assisted or open lobectomy surgery occurred. We used propensity score matching and inverse probabilistic weighting to account for selection bias. Survey-specific logistic and quantile regression models were applied to determine the difference between minimal invasive surgical procedures for adverse perioperative outcomes compared to the open approach.
Results
We identified 26,140 eligible cases of which 5,337 (20.4%), 12,680 (48.5%), and 8123 (31.1%) underwent RL, VL, and OL. We found that both RL and VL were associated with lower overall complication rates, shorter lengths of stay, and fewer mortality risks. RL was associated with significantly elevated risks for perioperative respiratory complications (aOR 1.10, 95%CI 1.02–1.19, p = 0.010) despite the lower risk for bleeding events (aOR 0.81, 95%CI 0.72–0.92, p = 0.001) when compared to VL.
Conclusion
While we found relatively low rates of perioperative complications for VL, and RL compared to OL, higher respiratory complication rates in RL is concerning. Such findings are useful in shared decision-making regarding surgical approaches with prospective patients.
Parasites of invasive pink salmon, Oncorhynchus gorbuscha (Walbaum, 1792) (Actinopterygii: Salmonidae), in the Kandalaksha Bay of the White Sea
Authors: Sokolov Sergey , Ieshko Evgeny , Gordeeva Natalia , Gorbach Vyacheslav , Parshukov Aleksey 
Published: April 2023

Abstract
Pink salmon, Oncorhynchus gorbuscha (Walbaum, 1792), a native of the North Pacific Ocean, is an invasive fish species rapidly expanding in the North Atlantic, the adjacent waters of the Arctic Ocean, and rivers in their watersheds. We investigated the species composition of parasites and the structure of parasite communities of the introduced pink salmon in Kandalaksha Bay of the White Sea in 2021. The parasites were identified using morphological and genetic methods. A total of 14 parasite species were recorded. The core species of the parasitic fauna of the introduced pink salmon in the Kandalaksha Bay were Clistobothrium montaukense Ruhnke, 1993, ʽDiphyllobothriumʼ spp., Scolex polymorphus (plerocercoids), Brachyphallus crenatus (Rudolphi, 1802), Derogenes varicus (Müller, 1784), Lecithaster salmonis Yamaguti, 1934 (adults), Anisakis simplex (Rudolphi, 1809) sensu stricto (juvenile III) and Hysterothylacium aduncum (Rudolphi, 1802) (juveniles III and IV). Plerocercoids of C. montaukense were first detected in fish from the polar waters of the Northern Hemisphere. We provided the first evidence that the Pacific genetic lineage of A. simplex sensu stricto occurs in European marine waters. In 2021, there was a noticeable increase in the mean abundance of the third-stage juveniles of Anisakis in the White Sea pink salmon compared to the period of 1990s-early 2000s. We conclude that the pink salmon occupies the same trophic niche in the new region of its introduction as in the native range.
The effects of electronic head-mounted displays in vision rehabilitation for patients with tunnel vision
Authors: Xu Dongye , Yu Manrong , Zheng Changyue , Ji Shunmei , Dai Jinhui 
Published: April 2023

Abstract
Purpose: To investigate the effect of a new head-mounted electronic visual aid-Acesight on improving visual function and daily activities in patients with tunnel vision.
Methods: 57 patients with tunnel vision participated in this study. The visual field (VF), visual acuity (VA), search ability, time of finding people from the side (TFPS), walking ability and the subjective feelings of patients with and without Acesight were measured.
Results: 15 (36%) patients thought Acesight was “helpful,” 16 (28%) thought it was “a little help,” and 26 (46%) believed that it was “not helpful.” The proportion of people aged < 60 years found Acesight helpful was higher. When wearing Acesight, the average horizontal VF diameter (°) (35.54[8.72]) and vertical VF diameter (°) (26.63[5.38]) were larger than those without visual aids (20.61[9.22], 18.19[6.67]) (P all < 0.001). The average TFPS before and while wearing the Acesight was 1.77s(0.32) and 1.19s(0.29), respectively (t = 14.28, P < 0.001). The average search times, number of collisions, walking speeds when wearing the Acesight were not statistically different from those without visual aids (P all > 0.05).
Conclusion: More than half of patients with tunnel vision found the Acesight helpful, and a higher proportion of those aged < 60 years old found it helpful. Acesight can expand the horizontal and vertical VF of patients with tunnel vision and can enable patients to detect objects coming from the side earlier.
Open surgery with a lateral neck approach in cases of foreign body impaction that penetrating the neck through the oesophagus: single- centre experience
Authors: Xu Feng , Shen Na , Liu Danzheng 
Published: April 2023

Abstract
Purpose
Because the cases are quite scare, we aimed to review cases of foreign body impaction penetrating the neck through the oesophagus to analyze the characteristics of these cases. The open surgery skills of the surgeon, the treatment procedure and the surgeons’ experience in the rare diseases were analyzed.
Methods
We collected and analyzed all cases from 2015–2020 in our hospital. The surgical skill and procedures for fasting and anti-infection treatment was studied retrospectively. Following up was with telephone communication.
Results
Our series included fifteen cases. Tenderness in the pre-cervical site was a physical sign for screening. Thirteen cases underwent a lateral neck open surgery with the incision including the left side of neck and only two cases were incised from the right side of the neck. Pus was found 3 days after the impaction in one case, the shortest time observed in our series. the oesophageal laceration was only sutured primarily in 5 cases (33.33%) in all fifteen casas. After sufficient drainage (average more than 9 days), antibiotic treatment and fasting (normally 2–3 weeks), the patients gradually began changing to solid foods from fluids after complete blood count and oesophageal radiography result confirmations. No severe complications occurred, and all the patients have no swallowing dis-function and recovered well.
Conclusion
The surgery should be performed as soon as possible after impaction. The lateral neck approach surgery and the therapeutic procedure introduced in this article are safe and effective treatments.
Association of gynecomastia and fatty liver and epicardial fat in COVID-19 patients
Authors: Livani Somayeh , Fatemi Alireza , Aqerkakli Karim , Tabrizi Mohammad Mohajer 
Published: April 2023

Abstract

Objectives:We aimed to determine the association between gynecomastia, hepatic steatosis through liver density and epicardial fat thickness in CT-scans of COVID-19 patients.Methods and Materials:In this descriptive-analytical cross-sectional study, Gynecomastia, fatty liver and epicardial fat were measured using CT-scan. The collected data were analyzed using Graphpad Prism 9 software. A significance level of less than 0.05 was considered.Results:Among 341 men hospitalized with COVID-19 infection, 35 (10%) were admitted to intensive care unit (ICU) and 62 (18%) died. The prevalence of gynecomastia and fatty liver was 35% and 20% respectively. Patients' age had a direct positive correlation with mortality (r=0.21, P<0.001) and epicardial fat (r=0.28, P<0.001). Bilateral gynecomastia was not associated with mortality or ICU admission, the prevalence of fatty liver, and the amount of epicardial and retro-areolar fat. However, right-sided gynecomastia was associated with the prevalence of fatty liver (r=0.11 and P=0.05) and left-sided gynecomastia was associated with epicardial fat (r=0.14 and P=0.01). In this study, the prevalence of fatty liver was positively correlated to the amount of epicardial fat (r = 0.12, P = 0.02) and retro-areolar fat (r = 0.34, P < 0.001).Conclusion:Bilateral gynecomastia was not associated with mortality or ICU admission, prevalence of fatty liver, and epicardial and retro-areolar fat volume. But right-sided gynecomastia was associated with the prevalence of fatty liver and left sided gynecomastia was associated with epicardial fat. The amount of retro-areolar fat was recognized as a risk factor for the death of patients.
Identifying Suspicious Fishing Activity based on AIS Disabling Events
Authors: Agarwal Anmaya , Gala Jay , Mantha Saketh , Katariya Yash , Kanikar Prashasti 
Published: April 2023

Abstract
A staggering loss of US$10 billion to US$23 billion is incurred each year due to illegal, unreported, and unregulated (IUU) fishing activities along with a severe loss to biodiversity. The Automatic Identification System (AIS), is a tool used to track vessel activity and avoid collisions. It is now being used to detect IUU activities as well, but it has a major drawback as the AIS transponders could be disabled due to various reasons, either illegal or otherwise, hence reducing its effectiveness. According to Welch et al. (2022), more than 55,000 suspected intentional disabling events (> 4.9M hours) occurred between 2017 and 2019. Thus the need for much more sophisticated global surveillance has increased and algorithms to analyze such huge amounts of data are required. We present a machine learning solution based on historical data to detect vessels of interest using the AIS Disabling Events dataset obtained from the Global Fishing Watch combined with the Regional Fisheries Management Organizations (RFMOs) datasets containing details of vessels caught in IUU fishing activities previously within their respective regions. One of our best models is the XGBoost with cost-sensitive learning boasting a minority recall of 0.79 and a majority recall of 0.76.
Diagnostic Performance of Quantitative Flow Ratio in Non-ST Elevation Acute Coronary Syndromes in Comparison to Non-Hyperemic Pressure Ratios. A prospective study
Authors: Liontou Catherine , Kalogera Vasiliki , Oikonomou Dimitrios , Stalikas Dimitrios , Pappas Loukas , Triantafyllou Konstantinos 
Published: April 2023

Abstract
Purpose
Quantitative Flow Ratio (QFR) is a new angiography-based coronary physiology tool aimed to evaluate functional relevance of intermediate coronary lesions. Aim of the study is to assess diagnostic performance of QFR in patients with non-ST-elevation acute coronary syndrome (NSTE-ACS) in comparison to currently used non-hyperaemic pressure ratios (NHPRs).
Methods
In this prospective, single-centre study, coronary physiology of intermediate coronary stenoses of non-culprit vessels in patients presenting with NSTE-ACS was evaluated using NHPRs (iFR, DFR or RFR). Subsequently, QFR was computed offline by a QFR analyst blinded to the NHPR results. Diagnostic performance of QFR was assessed in comparison to NHPRs as reference standard.
Results
A total of 60 vessels with intermediate coronary stenoses was investigated. The NHPRs were used as follows: RFR 38%, DFR 47% and iFR 15% of the cases. The NHPR result was positive, showing significant lesion, in 19 cases. A significant correlation was found between NHPR and QFR (r = 0.84, p < 0.001). Classification agreement of the two methods (95%) and diagnostic performance of QFR in comparison to NHPR (AUC: 0.962 [0.914–1.00]) were both high. Sensitivity, specificity, positive and negative predictive value of QFR in comparison to NHPR were 84.2%, 100%, 100% and 93.2% respectively.
Conclusion
QFR has high diagnostic performance in detecting functionally significant lesions of non-culprit arteries in patients with NSTE-ACS and multivessel disease. Due to its high negative predictive value, it can be used to safely avoid unnecessary invasive physiological assessment of these lesions.
Tittle: First drug-checking study at an electronic festival and fentanyl detection in the central region of Mexico
Authors: Cruz Silvia L. , Bencomo-Cruz Miguel , Medina-Mora María E. , Vázquez-Quiroz Fabiola , Bautista Clara Fleiz 
Published: April 2023

Abstract
Background: Perception of drug adulteration has increased in Mexico, but there is little research on adulterants and toxicity. The aim of this study was to identify drug composition in an electronic music outdoor festival nearby Mexico City.
Methods: The participants completed a questionnaire with demographic data, harm reduction strategies, drug-use patterns, history, and the drug they expected to find. We took a small sample of each substance and prepared it for drug checking. In the setting a two-section drug testing station was placed within the grounds of the festival. Interaction with participants occurred at the front part. Drug checking was conducted at the rear part. The service was free of charge, voluntary and confidential. Forty persons aged 22 to 48 years participated (mode= 28), of which 92.5% were male, most (82.5%) were single. Through the Substance Analysis Program of ReverdeSer Colectivo, we conducted the testing with the attendants that provided 51 drug samples, following ethical and biosafety protocols. We used colorimetry, Fourier Transform Infrared Spectroscopy, and fentanyl immunoassay strips for sample analysis.
Results: Substances of choice among attendants were psychostimulants (MDMA and other amphetamine-like drugs) and hallucinogens. Most samples contained what the users expected plus adulterants. Main adulterants were methylene-dioxy-ethyl-amphetamine, methylene-dioxy-propyl-amphetamine, hydroxyamphetamine, and the selective serotonin reuptake inhibitor venlafaxine. Fentanyl was present in 2 out of 4 cocaine samples and in 14 of the 22 confirmed MDMA samples.
Conclusions: Some of the adulterants found pose serious health risks, especially fentanyl, amphetamine-like substances, and venlafaxine. Therefore, it is urgent to monitor these adulterants at electronic music festivals and to implement prevention, treatment, and harm reduction public policies. Naloxone distribution and drug-assisted therapies should be part of government programs in Mexico.