bluuebunny/crossref_metadata_2025_split huggingface dataset:
From Colonial Subjecthood to Shared Humanity: Social Work and the Politics of “Doing” in Kamaladevi Chattopadhyay's International Thought
Authors: Balaji Shruti 
Published: March 2023

AbstractThis article tracks a paradox in elite, Third-World thinkers’ nation-building and postcolonial world-making in the early to mid-twentieth century. The tension lay in highly universalized notions of equality in imagined postcolonial worlds and the hierarchized social organizing tactics required to bring these worlds to life. The paper examines Kamaladevi Chattopadhyay—a prominent Indian social activist—and her international thought as she encountered this paradox in her social work praxis. I assess Kamaladevi's social work politics in the 1920s and 1930s at the Congress Seva Dal (a mass-based voluntary organization) as an imperial site where her universalized ideas about subjecthood clashed with practical disciplinary and hierarchical modes of political engagement. Then, I explore Kamaladevi's alienation from party politics in a newly independent India in the 1940s, which offered her an alternative pathway to leverage her social work as she built anticolonial solidarities at the substate level. Reading new archival material from Kamaladevi's travels in West Asia and parts of Africa in the 1950s–1960s, I suggest that her anti-imperial and race-conscious international thought in the “postimperial” world is a continuation rather than a breakaway from the earlier tensions of her normative and hierarchical civil–society activism. Kamaladevi's specific political trajectory that cuts across the Indian independence divide in 1947 is interesting in two ways. First, it problematizes hierarchies in historical elite Indian women's anticolonial and civil–society activism. Second, examining her social work allows for a disruptive reading of taken-for-granted binaries of the colonial/postcolonial, local/international, and social/political in historical international thought.
Multiple antibiotic resistance index (MARI) of human-isolated Salmonella species: a practical bacterial antibiotic surveillance tool
Authors: Woh Pei Yee , Yeung May Pui Shan , Goggins William Bernard 
Published: March 2023

Abstract

Objectives
Drug-resistant Salmonella plays a significant role in disease morbidity and mortality worldwide. The present study aimed to determine the multiple antibiotic resistance index (MARI) of Salmonella isolated from children hospitalized for gastroenteritis in Hong Kong.

Methods
Salmonella isolates from stool samples of children aged from 30 days to &lt;5 years were confirmed by using MALDI-TOF MS and subjected to serotyping methods according to the White–Kauffmann–Le Minor scheme. Antimicrobial susceptibility was determined by agar disc diffusion.

Results
A total of 101 Salmonella isolates were serogrouped into Group B (n = 46, 45.5%), Group C (n = 9, 9.0%) or Group D (n = 46, 45.5%), and successfully classified into S. Enteritidis (n = 15) and S. Typhimurium (n = 7). Overall Salmonella susceptibilities demonstrated the highest level of resistance to ampicillin (76.2%), ciprofloxacin (54.0%) and tetracycline (61.2%) whereas MDR strains had high resistance toward ampicillin (100%), tetracycline (100%), cotrimoxazole (84.6%), chloramphenicol (83.3%) and ciprofloxacin (83.3%). MARI revealed that 80.2% of Salmonella including all MDR strains (n = 13) had indexes greater than 0.2.

Conclusions
The MARI captures a snapshot of a high rate of antibiotic use and resistance in the isolated Salmonella, indicating the urgent need for continuous antimicrobial susceptibility surveillance and control of antibiotic prescription in selecting effective treatments for human diseases.
Msp1-mediated proofreading mechanism for localization of tail-anchored membrane proteins
Authors: Matsumoto Shunsuke 
Published: March 2023

Abstract
Protein targeting to organelles has been thought to be a very precise process, and proteins that fail to localize correctly are rapidly degraded. Tail-anchored proteins are posttranslationally targeted to the endoplasmic reticulum membrane via guided entry of tail-anchored (TA) proteins pathway. However, these proteins can be mislocalized to the mitochondrial outer membrane. We found that the AAA-ATPase Msp1 on the mitochondrial outer membrane extracts mislocalized TA proteins to the cytosol, passing them to the guided entry of the TA proteins pathway to facilitate their transfer to the endoplasmic reticulum membrane. After the transfer to the endoplasmic reticulum, such TA proteins are directed to degradation if they are recognized by the quality control system on the endoplasmic reticulum. If not recognized, they are retargeted to their original destination along the secretory pathway. Thus, we have identified an intracellular proofreading system that corrects the localization of TA proteins.
Collecting the nation in the museum of the Society of Antiquaries of Scotland, 1832–91
Authors: Holder Julie 
Published: March 2023

Abstract
The sixty-year period from 1832 to 1891 was key to the development of the Society of Antiquaries of Scotland and its museum, during which time its collection was transferred to national ownership and greater emphasis began to be placed on social and cultural history. This article analyses acquisition data to add substance to the knowledge of the meanings attached by the antiquarian society to the collection of Scottish materials from the period after ad 1100. Its purpose is, first, to ascertain the extent to which the society developed targeted collecting strategies and, second, to demonstrate the ways in which the museum’s collecting practices were influenced by the society’s priorities and broader antiquarian ideas on the value of material sources in the study of history. It is argued that by 1891 the museum’s collecting strategies had shifted from a unionist-nationalist framework towards an international comparative approach which elevated the ‘Scottishness’ of the museum’s collection by representing Scotland as a distinct nation of Europe with its own recognizable material history.
Bayesian likelihood-based regression for estimation of optimal dynamic treatment regimes
Authors: Yu Weichang , Bondell Howard D 
Published: March 2023

Abstract
Clinicians often make sequences of treatment decisions that can be framed as dynamic treatment regimes. In this paper, we propose a Bayesian likelihood-based dynamic treatment regime model that incorporates regression specifications to yield interpretable relationships between covariates and stage-wise outcomes. We define a set of probabilistically-coherent properties for dynamic treatment regime processes and present the theoretical advantages that are consequential to these properties. We justify the likelihood-based approach by showing that it guarantees these probabilistically-coherent properties, whereas existing methods lead to process spaces that typically violate these properties and lead to modelling assumptions that are infeasible. Through a numerical study, we show that our proposed method can achieve superior performance over existing state-of-the-art methods.
Enhanced safety surveillance of STAMARIL® yellow fever vaccine provided under the expanded access investigational new drug program in the USA
Authors: Rojas Andrey , Hachey Wayne , Kaur Gurpreet , Korejwo Joanna , Muhammad Riyadh 
Published: March 2023

Abstract

Background
YF-VAX® (Sanofi, Swiftwater, PA), a live, attenuated vaccine based on the yellow fever (YF) substrain 17D-204, is the only YF vaccine licensed in the USA. Manufacturing disruption of YF-VAX and anticipated depletion of the US supply by mid-2017 led to the importation of another YF vaccine, STAMARIL® (Sanofi, France), into the USA under an expanded access investigational new drug program (EAP) to fulfil the public health need for YF vaccination. As part of this program, Sanofi collected enhanced safety surveillance data following vaccination with STAMARIL. Here, we report the results of the enhanced safety surveillance.

Methods
STAMARIL vaccine was offered to those aged ≥9 months at high risk of YF. Vaccine recipients (or parents/guardians) were instructed to report suspected adverse reactions, any serious adverse events (SAEs) including adverse events of special interest [AESI] occurring after vaccination regardless of suspected relationship, and any inadvertent exposure in pregnancy or breastfeeding within 14 days of vaccination. The AESIs monitored were anaphylaxis, neurotropic disease (YEL-AND) and viscerotropic disease (YEL-AVD).

Results
Overall, 627 079 individuals received STAMARIL from May 2017 through June 2021; of these, 1308 (0.2%) reported at least one AE, of which 122 reported at least one SAE. There were seven cases of YEL-AND and three cases of YEL-AVD reported, for reporting rates of 1.1 and 0.5 per 100 000 vaccine recipients, respectively. One vaccine recipient developed an anaphylactic reaction (reporting rate: 0.16 per 100 000). No safety concerns were identified from inadvertent vaccine exposure during pregnancy (41 pregnant women) or potential neonatal exposure via breast milk (four exposed infants).

Conclusions
This study supports the utility of STAMARIL in the EAP as an alternative solution for the YF vaccine shortage in the USA. SAEs were very rare and consistent with the known safety profile of STAMARIL.
Stroke Care
Authors: Harwood Rowan H. , Huwez Farhad Umer , Guyler Paul , Alam Sajid , Gaynor Catherine 
Published: March 2023

Abstract
Stroke Care looks into a holistic approach to the care of patients with transient ischaemic attacks (TIA) and stroke. It acknowledges stroke as a major health concern across the world that is common but complicated to manage. Evidence shows that thorough and organized care from teams of health professionals in stroke units leads to substantially fewer deaths and better recovery than other types of care. The book elaborates on the skills needed to address the issues around a stroke patient’s journey from diagnosis and life at home. Practice recommendations involve evidence supporting prevention, acute care, rehabilitation, and long-term care in line with the changes in the field of stroke medicine and the latest clinical trials.
Leveraging the metacoupling framework for sustainability science and global sustainable development
Authors: Liu Jianguo 
Published: March 2023

ABSTRACT
Sustainability science seeks to understand human–nature interactions behind sustainability challenges, but has largely been place-based. Traditional sustainability efforts often solved problems in one place at the cost of other places, compromising global sustainability. The metacoupling framework offers a conceptual foundation and a holistic approach to integrating human–nature interactions within a place, as well as between adjacent places and between distant places worldwide. Its applications show broad utilities for advancing sustainability science with profound implications for global sustainable development. They have revealed effects of metacoupling on the performance, synergies, and trade-offs of United Nations Sustainable Development Goals (SDGs) across borders and across local to global scales; untangled complex interactions; identified new network attributes; unveiled spatio-temporal dynamics and effects of metacoupling; uncovered invisible feedbacks across metacoupled systems; expanded the nexus approach; detected and integrated hidden phenomena and overlooked issues; re-examined theories such as Tobler's First Law of Geography; and unfolded transformations among noncoupling, coupling, decoupling, and recoupling. Results from the applications are also helpful to achieve SDGs across space, amplify benefits of ecosystem restoration across boundaries and across scales, augment transboundary management, broaden spatial planning, boost supply chains, empower small agents in the large world, and shift from place-based to flow-based governance. Key topics for future research include cascading effects of an event in one place on other places both nearby and far away. Operationalizing the framework can benefit from further tracing flows across scales and space, uplifting the rigor of causal attribution, enlarging toolboxes, and elevating financial and human resources. Unleashing the full potential of the framework will generate more important scientific discoveries and more effective solutions for global justice and sustainable development.
Successful Treatment of Persistent Stenotrophomonas maltophilia Bacteremia With Cefiderocol in an Infant
Authors: Hsu Alice J , Simner Patricia J , Bergman Yehudit , Mathers Amy J , Tamma Pranita D 
Published: March 2023

Abstract
Stenotrophomonas maltophilia is an important nosocomial pathogen with limited treatment options. Trimethoprim-sulfamethoxazole (TMP-SMX) is generally regarded as the preferred therapy; however, treatment failures with TMP-SMX have been reported. Herein, we report a case of a 5-week-old infant with 8 days of S. maltophilia bacteremia while receiving TMP-SMX, despite in vitro susceptibility. Transitioning to cefiderocol monotherapy resulted in blood culture clearance within 24 hours, in the absence of any additional interventions. This is the first published case of the use of cefiderocol for a pediatric patient with an infection due to S. maltophilia. We review preclinical and clinical data that underscore why cefiderocol may be an effective treatment option for S. maltophilia infections.
Diagnosing Institutionalized ‘Distrustworthiness’
Authors: Fricker Miranda 
Published: March 2023

Abstract
I consider Katherine Hawley's commitment account of interpersonal trustworthiness alongside her sceptical challenge regarding the value of philosophically modelling institutional trustworthiness as distinct from reliability. I argue, pace Hawley's challenge, that there would be significant diagnostic and explanatory loss if we were to content ourselves with ideas of institutional (un)reliability alone; and I offer an illustrative case where institutional unreliability is only the half of it, indicating that when it comes to certain kinds of institutional dysfunction, we do need philosophical models of institutional ‘distrustworthiness’ if we are to achieve a proper diagnosis.
Arsenic impairs stem cell differentiation via the Hippo signaling pathway
Authors: Perego M Chiara , McMichael Benjamin D , Bain Lisa J 
Published: March 2023

Abstract
Arsenic is a ubiquitous toxic metalloid, with over 150 million people exposed to arsenic concentrations above the current 10 ppb drinking water standard through contaminated food and water. Arsenic is a known developmental toxicant as neuronal and muscle development are disrupted following arsenic exposure during embryogenesis. In this study, murine embryonic stem cells were chronically exposed to 0.1 μM (7.5 ppb) arsenic for 32 weeks. RNA sequencing showed that the Hippo signaling pathway, which is involved in embryonic development and pluripotency maintenance, is impaired following arsenic exposure. Thus, temporal changes in the Hippo pathway’s core components and its downstream target genes Ctgf and c-Myc were investigated. Protein expression of the pathway’s main effector YAP in its active form was significantly upregulated by 3.7-fold in arsenic-exposed cells at week 8, while protein expression of inactive phosphorylated YAP was significantly downregulated by 2.5- and 2-fold at weeks 8 and 16. Exposure to arsenic significantly increased the ratio between nuclear and cytoplasmic YAP by 1.9-fold at weeks 16 and 28. The ratio between nuclear and cytoplasmic transcriptional enhancer factor domain was similarly increased in arsenic-treated samples by 3.4- and 1.6-fold at weeks 16 and 28, respectively. Levels of Ctgf and c-Myc were also upregulated following arsenic exposure. These results suggest that chronic exposure to an environmentally relevant arsenic concentration might hinder cellular differentiation and maintain pluripotency through the impairment of the Hippo signaling pathway resulting in increased YAP activation.
Captive Cousins: Hoomothya, Wassaja, and a Lifetime of Unwellness
Authors: Crandall Maurice 
Published: March 2023

Abstract
This article explores the lives and experiences of two Yavapai first cousins during the late nineteenth and early twentieth centuries. One of these men was very well known (Wassaja, or Carlos Montezuma), while the other was less so (Hoomothya, or Mike Burns). While both secured American citizenship and a degree of success in mainstream American society, their lives were also plagued by bitter disappointments and personal turmoil. Using the Yavapai concept of nagock hona umi—a Yavapai term meaning unwellness in an individual—the article demonstrates how and why these two Yavapai cousins experienced profound, lifelong unwellness. This unwellness began in childhood, when both were captured by enemies and ripped from their families, and it remained untreated throughout their lives. This article serves as an invitation to scholars to utilize Indigenous methodologies originating from Indigenous communities to better understand how they experienced—and continue to experience—colonialism, genocide, assimilation policies, citizenship and liberalism, and life in the “modern” world.
Epidemiology, Host Resistance, and Genomics of the Small Grain Cereals PathogenXanthomonas translucens: New Advances and Future Prospects
Authors: Ledman Kristi E. , Osdaghi Ebrahim , Curland Rebecca D. , Liu Zhaohui , Dill-Macky Ruth 
Published: March 2023

Bacterial leaf streak (BLS) primarily affects barley and wheat and is mainly caused by the pathogens Xanthomonas translucens pv. translucens and X. translucens pv. undulosa, respectively. BLS is distributed globally and poses a risk to food security and the supply of malting barley. X. translucens pv. cerealis can infect both wheat and barley but is rarely isolated from these hosts in natural infections. These pathogens have undergone a confusing taxonomic history, and the biology has been poorly understood, making it difficult to develop effective control measures. Recent advancements in the ability and accessibility to sequence bacterial genomes have shed light on phylogenetic relationships between strains and identified genes that may play a role in virulence, such as those that encode Type III effectors. In addition, sources of resistance to BLS have been identified in barley and wheat lines, and ongoing efforts are being made to map these genes and evaluate germplasm. Although there are still gaps in BLS research, progress has been made in recent years to further understand epidemiology, diagnostics, pathogen virulence, and host resistance.
Anaesthesia and cancer recurrence: the influence of perioperative anaesthetic technique on cancer recurrence after surgery
Authors: Rahmani Lua S. , Abdelaatti Ahmed , Wall Thomas P. , Buggy Donal J. 
Published: March 2023

Purpose of review
Cancer is a leading cause of death worldwide, and incidence is increasing. Excisional surgery is essential in approximately 70% of solid organ tumours. Emerging research in onco-anaesthesiology suggests that perioperative anaesthetic and analgesic techniques might influence long-term oncologic outcomes.

Recent findings
Prospective, randomized control trials (RCTs) demonstrate that perioperative regional and neuraxial anaesthetic techniques do not affect cancer recurrence. Ongoing trials are investigating the potential outcome benefits of systemic lidocaine. Retrospective studies indicate improved postoperative oncologic outcomes for certain types of breast cancer with higher intraoperative opioid dosage, nuancing available evidence on the effect of opioids. RCT evidence suggests that propofol has no beneficial effect compared with volatiles on breast cancer recurrence, although it remains unclear whether this applies to other cancer types.

Summary
Although regional anaesthesia definitively does not affect cancer recurrence, ongoing prospective RCTs with oncological outcomes as primary endpoints are awaited to establish if other anaesthetic or analgesic techniques influence cancer recurrence. Until such trials conclusively identify a causal relationship, insufficient evidence exists to recommend specific anaesthetic or analgesic techniques for tumour resection surgery based on altering the patient's risk of recurrence.
Absorbance Measurements From Normal-hearing Ears in the National Health and Nutrition Examination Survey, 2015–2016 and 2017–2020
Authors: Sun Jiayi , Horton Nicholas J. , Voss Susan E. 
Published: March 2023

Objective:
To summarize absorbance and impedance angles from normal-hearing ears within the 2015–2016 and 2017–2020 US National Health and Nutrition Examination Surveys (NHANES).

Design:
Two publicly available NHANES datasets were analyzed. Ears meeting criteria for normal hearing and valid absorbance and impedance angle measurements were identified. Measurements were summarized via descriptive statistics within categories of age cohort, race/ethnicity cohort, sex (male, female), and ear (left, right).

Results:
A total of 7029 ears from 4150 subjects, ages 6 to 80 years, met inclusion criteria. Differences between subgroups within all categories (age, race/ethnicity, sex, and ear) were fractions of the sample SDs. The largest differences occurred between age cohorts younger than 20 years.

Conclusions:
The NHANES absorbance and impedance angle measurements are consistent with published literature. These results demonstrate that trained professionals, using the Titan instrument in a community setting inclusive of all demographics, produce comparable measurements to those in laboratory settings.
Applying TEC-VARIETY to Motivate and Engage Learners for Online Learning Success
Authors: Chen Weichao , Bonk Curtis J. , Sandars John 
Published: March 2023

Abstract:Learner motivation plays an essential role in overcoming barriers to achieve online learning success. Many health professions educators, however, are not familiar with evidence-based motivational principles and techniques that tap into learners' inner resources to promote online learning success. The TEC-VARIETY (T-Tone; E-Encouragement; C-Curiosity; V-Variety; A-Autonomy; R-Relevance; I-Interactivity; E-Engagement; T-Tension; and Y-Yielding products) framework provides evidence-based principles and techniques that motivate and engage learners. Health professions educators can identify and assemble appropriate activities to motivate and engage online learners. Educators are encouraged to use Design-Based Research to guide their adoption of TEC-VARIETY and evaluation of outcomes.