bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Penggunaan Metode Speed Reading Terhadap Kemampuan Membaca Cepat Siswa
Authors: Rahayu Sri , Jannah Miftahul 
Published: May 2023

This study aims to determine the effect of the speed reading method on the speed reading ability of fifth grade students at SD Negeri 20 Alesipitto, Ma'rang District, Pangkep Regency. The type of research used by researchers is experimental, which means that research is used to look for the effect of certain treatments on others under controlled conditions. The population and sample of this study were all of the fifth grade students at SD Negeri 20 Alesipitto, totaling 11 people, and the sample was all of the fifth grade students at SD Negeri 20 Alesipitto, totaling 11 people. Data was collected using observation and also tests, the data collected was analyzed using pretest and posttest. The results showed that the results of the ability to read fast before being taught using speed reading the level of mastery was in the medium category, after using the speed reading method it reached the high category. So it can be concluded that the speed reading method can be used to improve students' speed reading skills, some of the advantages are that it can activate students during the learning process, attract students' attention and make it easier for students to understand.
ABSTRAK
Penelitian ini bertujuan untuk mengetahui pengaruh metode speed reading terhadap kemampuan membaca cepat siswa kelas V SD Negeri 20 Alesipitto Kecamatan Ma’rang Kabupaten Pangkep. Jenis penelitian yang digunakan oleh peneliti yaitu eksperimen, yang artinya penelitian yang digunakan untuk mencari pengaruh perlakuan tertentu terhadap yang lain dalam kondisi yang terkendalikan. Populasi dan sampel penelitian ini yaitu populasinya seluruh siswa kelas V SD Negeri 20 Alesipitto yang berjumlah 11 orang, dan sampelnya yaitu keseluruhan siswa kelas V SD Negeri 20 Alesipitto yang berjumlah 11 orang. Data dikumpulkan menggunakan observasi dan juga tes, data yang dikumpulkan dianalisis menggunakan pretest dan posttest. Hasil penelitian menunjukkan bahwa hasil kemampuan membaca cepat sebelum di ajar dengan menggunakan speed reading tingkat penguasaan berada pada kategori sedang, setelah menggunakan metode speed reading mencapai kategori tinggi. Maka dapat disimpulkan bahwa metode speed reading dapat digunakan untuk meningkatkan kemampuan membaca cepat siswa, beberapa keuntungannya yaitu dapat mengaktifkan murid pada saat proses pembelajaran berlangsung, menarik perhatian murid dan mempermudah pemahaman murid.
Penerapan Model Cooperative Script untuk Meningkatkan Keterampilan Siswa Membaca Teks Eksposisi
Authors: Mardewi Mardewi , Mansyur Umar 
Published: May 2023

This study aims to describe the increase in reading ability of exposition texts of Class X students of SMA Negeri 18 Makassar by using the cooperative script model. The type of research used was Classroom Action Research (PTK) which was carried out in two cycles. Each cycle is held in two meetings, including giving tests at the end of each cycle. PTK research procedures in this study include planning activities, implementation of actions, observation, and reflection. The subjects of this study were students of class X SMA Negeri 18 Makassar, which consisted of 35 students. The results showed that the use of the cooperative script learning model proved to be effective in improving students' reading text exposition skills, especially during the activity of finding and searching for the essence of the exposition text, as well as students' enthusiasm and active participation when participating in group discussion activities. The increase in students' reading skills is evidenced by the average score of students in each cycle, which increased by 60% in cycle I, and in cycle II it became 89%. Thus, the application of the cooperative script model is proven to be able to improve the skills of reading expository texts of Class X students of SMA Negeri 18 Makassar.
ABSTRAK
Penelitian ini bertujuan mendeskripsikan peningkatan kemampuan membaca teks eksposisi siswa Kelas X SMA Negeri 18 Makassar dengan menggunakan model cooperative script. Jenis penelitian yang digunakan adalah Penelitian Tindakan Kelas (PTK) yang dilaksanakan sebanyak dua siklus. Setiap siklus dilaksanakan sebanyak dua kali pertemuan, termasuk pemberian tes di setiap akhir siklus. Prosedur penelitian PTK dalam penelitian ini meliputi kegiatan perencanaan, pelaksanaan tindakan, observasi, dan refleksi. Subjek penelitian ini adalah siswa kelas X SMA Negeri 18 Makassar, yang berjumlah 35 siswa. Hasil penelitian menunjukkan bahwa penggunaan model pembelajaran cooperative script terbukti efektif dalam meningkatkan keterampilan membaca teks eksposisi siswa, khususnya pada saat kegiatan menemukan dan mencari intisari dalam teks eksposisi, serta antusiasme dan partisipasi aktif siswa pada saat mengikuti kegiatan diskusi kelompok. Peningkatan keterampilan membaca siswa tersebut dibuktikan dengan perolehan nilai rata-rata siswa di setiap siklusnya, yakni meningkat sebanyak 60% pada siklus I, dan pada siklus II menjadi 89%. Dengan demikian, penerapan model cooperative script terbukti dapat meningkatan ketarampilan membaca teks eksposisi siswa Kelas X SMA Negeri 18 Makassar.
Crisis care for children and young people with mental health problems: national mapping, models of delivery, sustainability and experience (CAMH-Crisis2). A study protocol.
Authors: Bennett Clare , Hannigan Ben , Elliott Mair B , Elliott Martin , Evans Nicola , Fraser Claire , Hails Euan , Jones Aled , McMillan Iain , Pryjmachuk Steven , Sawle Leanne , Vaughan Rachael 
Published: May 2023

Background One in six five -16-year-olds have a probable mental health difficulty. Of these, almost half of older teenagers and a quarter of 11–16-year-olds report having self-harmed or attempted suicide. Currently, there is little research into mental health crisis services for young people, with little understanding of what services exist, who uses them, or what works best. Question ‘How are mental health crisis responses for children and young people up to the age of 25 sustained, experienced and integrated within their local systems of services’? Objectives 1. To describe National Health Service (NHS), local authority, education and third sector approaches to the implementation and organisation of crisis care for children and young people across England and Wales. 2. To identify eight contrasting case studies in which to evaluate how crisis services have developed and are currently organised, sustained, experienced and integrated within the context of their local systems of services. 3. To compare and contrast these services in the context of the available international evidence, drawing out and disseminating clear implications for the design and delivery of future crisis responses for children and young people and their families. Methods A sequential mixed methods approach, underpinned by normalisation process theory will be employed. A survey will create a detailed record of how crisis responses across England and Wales are organised, implemented and used. Subsequently, eight contrasting services in relation to geographic and socioeconomic setting, populations served, and service configuration will be identified as case studies. Interviews will be conducted with children, young people and parents/carers who have used the service, as well as commissioners, managers and practitioners. Operational policies and service usage data will also be examined. Analysis of how each service is provided, experienced, implemented and sustained will be conducted both inductively and deductively, reflecting normalisation process theory constructs.
Hubungan Siklus Menstruasi Terhadap Perfomance Atlet Atletik Lompat Jauh Putri PPLP Provinsi Bengkulu
Authors: Eben Ezer Pasaribu Rio , Yarmani  , Raibowo Septian 
Published: May 2023

Abstract
The problem in this study is that female long jump athletes often feel a decrease in performance during menstruation, this study examines the relationship between the menstrual cycle and the performance of female long jump athletes. While the purpose of the study was to determine whether or not there was a relationship between the menstrual cycle and the performance of female long jump athletes. This research method is quantitative. The population of this study were 20 female long jump athletes from PPLP Bengkulu Province. The data obtained by the results of the study with the correlation test obtained the rᵪᵧ= 0.912 > 0.444. It can be concluded that there is a relationship between the menstrual cycle and the performance of female long jump athletes in PPLP Bengkulu Province.
Keywords: Athletics, Long Jump, Menstrual Cycle, Performance
Desain Aplikasi Pencarian Jasa Fotografer (Capturar) dengan Menggunakan Metode Lean UX
Authors: Novialdi T  , Reski Mai Candra  , Muhammad Affandes  , Pizaini  
Published: May 2023

Fotografi sebagai bagian dari industri kreatif Indonesia merupakan sebuah industri yang mendorong penggunaan kreativitas individu. Fotografi juga berkembang seiring dengan bertambahnya manfaat fotografi di dalam kehidupan manusia. Pada dasarnya, fotografi dapat berhubungan dengan semua aspek industri karena kebutuhan foto dapat dijadikan sebagai dokumen penting. Perkembangan digital membuat pencarian barang dan jasa secara online sering ditemukan. Namun, pencarian jasa fotografer masih kurang maksimal karena belum adanya aplikasi khusus yang digunakan oleh fotografer dan pencari jasa fotografer. Pencarian fotografer yang dilakukan saat ini menggunakan metode konvensional, yaitu dengan mencari fotografer melalui rekomendasi teman ataupun keluarga serta melalui sosial media yang tidak diperuntukkan khusus pencarian jasa fotografer. Tujuan penelitian ini adalah untuk merancang desain prototipe aplikasi pencarian jasa fotografer berdasarkan aspek user interface (UI) dan user experience (UX). Penelitian menggunakan metode Lean UX yang terdiri dari 4 tahapan yaitu, Declare Assumptions, Create an Minimum Viable Product, Run an Experiment dan Feedback and Research yang menghasilkan asumsi permasalahan, rancangan prototipe, eksperimen internal dan pengujian usability. Hasil akhir penelitian ini adalah prototipe yang dibangun menggunakan aplikasi Figma. Prototipe telah diuji kepada 25 responden menggunakan pengujian System Usability Scale (SUS) yang menghasilkan nilai 82.
Cost-minimization analysis of HYQVIA® in the treatment of primary immunodeficiency disease (PID) and secondary immunodeficiency disease (SID) in Italy
Authors: Ravasio Roberto , Ripoli Silvia 
Published: May 2023

Background: Primary (PID) or secondary (SID) immunodeficiencies are diseases caused by quantitative and/or functional alterations of the different mechanisms involved in the innate and adaptive immune response. This economic evaluation was conducted to compare the cost of treatment of HYQVIA® (hyaluronidase-facilitated subcutaneous infusion of immunoglobulin, fSCIG) compared to intravenous immunoglobulin (IVIG) or subcutaneous immunoglobulin (SCIG), currently reimbursed in Italy, in the treatment of PIDs or SIDs.
Methods: A cost-minimisation analysis was carried out, considering the hospital’s perspective. The direct medical costs (cost of immunoglobulins and cost of administration) were assessed. The analysis was conducted considering one year (52 weeks) time horizon. The reference population included adult patients with PID with impaired antibody production or adult patients with SID with severe or recurrent infections, ineffective antimicrobial treatment and documented specific antibody defect (PSAF) or serum IgG level < 4 g/L.
Results: In the maintenance treatment of PID, HYQVIA® (€ 20,020.00) was the therapeutic alternative with the lowest mean annual cost compared to HIZENTRA® (€ 22,165.19) and VENITAL® (€ 24,967.68). Moreover, in the maintenance treatment of SIDs, HYQVIA® (€ 17,160.00) was the cost-saving therapeutic alternative compared to VENITAL® (€ 22,107.68). A sensitivity analysis confirmed the base case results.
Conclusion: Due to lower costs of administration and different scheme of administration, HYQVIA® was a cost-saving alternative to SCIG e IVIG in the treatment of PID and to IVIG in the treatment of SID
Evaluation of effectiveness of complex therapy for atopic dermatitis in children and adolescents using transcranial magnetic therapy
Authors: Iskra A. S. , Iskra E. L. , Suslova G. A. , Zaslavsky D. V. 
Published: May 2023

Today, the development and implementation of modern physiotherapeutic treatment options, including those safe for home use by patients, is promising.Purpose of the study. Studying the safety and effectiveness of transcranial magnetotherapy with mild and moderate severity of atopic dermatitis.Material and methods. The study was attended by 104 patients, aged 5 to 16 years, with a prescription of the disease from 2 months to 16 years. Patients were divided into groups: the 1st group received standard therapy, in the 2nd group they combined standard therapy and placebo in physiotherapeutic treatment, patients of the 3rd groups used transcranial therapy in monotherapy, participants of the 4th group were on combined therapy – transcranial magnetotherapy and standard.Results. According to the study, the effectiveness of transcranial magnetotherapy is based on a positive effect on the state of the central nervous system and its autonomic department, which is accompanied by the relief of clinical symptoms, itching and helps to improve psychoemotional status.Conclusions. The use of transcranial magnetotherapy in a complex with standard therapy helps to relieve clinical symptoms of atopic dermatitis and the quality of life of patients.
Hyperinsulinemia: an early biomarker of metabolic dysfunction
Authors: Vaidya Rama A. , Desai Sharvari , Moitra Panchali , Salis Sheryl , Agashe Shubhada , Battalwar Rekha , Mehta Anushree , Madan Jagmeet , Kalita Soumik , Udipi Shobha A. , Vaidya Ashok B. 
Published: May 2023

IntroductionHyperinsulinemia in the absence of impaired glucose tolerance and normal HbA1c is considered indicative of pre-diabetes. Very few Indian studies have focused on hyperinsulinemia particularly in young adults. The present study aimed to determine whether hyperinsulinemia may be present despite HbA1c being normal.MethodsThis was a cross–sectional study conducted on adolescents and young adults aged 16-25 years living in Mumbai, India. The participants attended various academic institutions and were those who underwent screening as the first step of a clinical trial for studying the efficacy of almond intake in prediabetes.ResultsAmong this young population (n=1313), 4.2% (n=55) of the participants were found to be prediabetic (ADA criteria) and 19.7% of them had HbA1c levels between 5.7%-6.4%. However, almost, 30.5% had hyperinsulinemia inspite of normal blood glucose levels and normal HbA1c. Among those with HbA1c&lt;5.7 (n=533), 10.5% (n=56) participants had fasting insulin&gt;15 mIU/L and a higher percentage (39.4%, n=260) had stimulated insulin above 80 mIU/L. These participants had higher mean anthropometric markers than those with normal fasting and/or stimulated insulin.ConclusionHyperinsulinaemia in the absence of impaired glucose tolerance and normal HbA1c may provide a much earlier indicator of detection for risk of metabolic disease and progression to metabolic syndrome and diabetes mellitus.
Knowledge mapping and current trends of global research on CRISPR in the field of cancer
Authors: Liu Han , Lv Zongwei , Zhang Gong , Wang Xia , Wang Yuan , Wang Kefeng 
Published: May 2023

Background: Gene editing tools using clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-related systems have revolutionized our understanding of cancer. The purpose of this study was to determine the distribution, collaboration, and direction of cancer research using CRISPR.Methods: Data from the Web of Science (WoS) Core Collection database were collected from 4,408 cancer publications related to CRISPR from 1 January 2013to 31 December 2022. The obtained data were analyzed using VOSviewer software for citation, co-citation, co-authorship, and co-occurrence analysis.Results: The number of annual publications has grown steadily over the past decade worldwide. The United States was shown, by far, to be the leading source of cancer publications, citations, and collaborations involving CRISPR than any other country, followed by China. Li Wei (Jilin University, China), and Harvard Medical School (Boston, MA, United States) were the author and institution with the most publications and active collaborations, respectively. The journal with the most contributions was Nature Communications (n = 147) and the journal with the most citations was Nature (n = 12,111). The research direction of oncogenic molecules, mechanisms, and cancer-related gene editing was indicated based on keyword analysis.Conclusion: The current study has provided a comprehensive overview of cancer research highlights and future trends of CRISPR, combined with a review of CRISPR applications in cancer to summarize and predict research directions and provide guidance to researchers.
Inhibitory effects of vaginal Lactobacilli on Candida albicans growth, hyphal formation, biofilm development, and epithelial cell adhesion
Authors: Takano Tomonori , Kudo Hayami , Eguchi Shuhei , Matsumoto Asami , Oka Kentaro , Yamasaki Yukitaka , Takahashi Motomichi , Koshikawa Takuro , Takemura Hiromu , Yamagishi Yuka , Mikamo Hiroshige , Kunishima Hiroyuki 
Published: May 2023

IntroductionAntifungal agents are not always efficient in resolving vulvovaginal candidiasis (VVC), a common genital infection caused by the overgrowth of Candida spp., including Candida albicans, or in preventing recurrent infections. Although lactobacilli (which are dominant microorganisms constituting healthy human vaginal microbiota) are important barriers against VVC, the Lactobacillus metabolite concentration needed to suppress VVC is unknown.MethodsWe quantitatively evaluated Lactobacillus metabolite concentrations to determine their effect on Candida spp., including 27 vaginal strains of Lactobacillus crispatus, L. jensenii, L. gasseri, Lacticaseibacillus rhamnosus, and Limosilactobacillus vaginalis, with inhibitory abilities against biofilms of C. albicans clinical isolates.ResultsLactobacillus culture supernatants suppressed viable fungi by approximately 24%-92% relative to preformed C. albicans biofilms; however, their suppression differed among strains and not species. A moderate negative correlation was found between Lactobacillus lactate production and biofilm formation, but no correlation was observed between hydrogen peroxide production and biofilm formation. Both lactate and hydrogen peroxide were required to suppress C. albicans planktonic cell growth. Lactobacillus strains that significantly inhibited biofilm formation in culture supernatant also inhibited C. albicans adhesion to epithelial cells in an actual live bacterial adhesion competition test.Discussion Healthy human microflora and their metabolites may play important roles in the development of new antifungal agent against C. albicans-induced VVC.
Efficacy of Xpert in tuberculosis diagnosis based on various specimens: a systematic review and meta-analysis
Authors: Gong Xue , He Yunru , Zhou Kaiyu , Hua Yimin , Li Yifei 
Published: May 2023

ObjectiveThe GeneXpert MTB/RIF assay (Xpert) is a diagnostic tool that has been shown to significantly improve the accuracy of tuberculosis (TB) detection in clinical settings, with advanced sensitivity and specificity. Early detection of TB can be challenging, but Xpert has improved the efficacy of the diagnostic process. Nevertheless, the accuracy of Xpert varies according to different diagnostic specimens and TB infection sites. Therefore, the selection of adequate specimens is critical when using Xpert to identify suspected TB. As such, we have conducted a meta-analysis to evaluate the effectiveness of Xpert for diagnosis of different TB types using several specimens.MethodsWe conducted a comprehensive search of several electronic databases, including PubMed, Embase, the Cochrane Central Register of Controlled Trials, and the World Health Organization clinical trials registry center, covering studies published from Jan 2008 to July 2022. Data were extracted using an adapted version of the Checklist for Critical Appraisal and Data Extraction for Systematic Reviews of Prediction Modeling Studies. Where appropriate, meta-analysis was performed using random-effects models. The risk of bias and level of evidence was assessed using the Quality in Prognosis Studies tool and a modified version of the Grading of Recommendations Assessment, Development, and Evaluation. RStudio was utilized to analyze the results, employing the meta4diag, robvis, and metafor packages.ResultsAfter excluding duplicates, a total of 2163 studies were identified, and ultimately, 144 studies from 107 articles were included in the meta-analysis based on predetermined inclusion and exclusion criteria. Sensitivity, specificity and diagnostic accuracy were estimated for various specimens and TB types. In the case of pulmonary TB, Xpert using sputum (0.95 95%CI 0.91–0.98) and gastric juice (0.94 95%CI 0.84–0.99) demonstrated similarly high sensitivity, surpassing other specimen types. Additionally, Xpert exhibited high specificity for detecting TB across all specimen types. For bone and joint TB, Xpert, based on both biopsy and joint fluid specimens, demonstrated high accuracy in TB detection. Furthermore, Xpert effectively detected unclassified extrapulmonary TB and tuberculosis lymphadenitis. However, the Xpert accuracy was not satisfactory to distinguish TB meningitis, tuberculous pleuritis and unclassified TB.ConclusionsXpert has exhibited satisfactory diagnostic accuracy for most TB infections, but the efficacy of detection may vary depending on the specimens analyzed. Therefore, selecting appropriate specimens for Xpert analysis is essential, as using inadequate specimens can reduce the ability to distinguish TB.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?RecordID=370111, identifier CRD42022370111.