bluuebunny/crossref_metadata_2025_split huggingface dataset:
Design and analysis of an inflatable recovery platform for shipborne UAV
Authors: Bo Dong , Lv Shengli 
Published: July 2023

Abstract
It is difficult to recover drones for small ships (such as destroyers). Therefore, it is necessary to design a new carrier-borne UAV recovery platform, achieving the purpose of rapid recovery of offshore UAV. This paper presents a fast unfolding and folding inflatable structure for small ship UAV offshore recovery. This paper analyze some static response of the UAV recovery platform. Firstly, parking positions of UAV on the runway surface is a factor. Secondly, runway surface materials is also a factor. Thirdly, airbag’s internal pressure also affects static response of the platform. It is find that static responses such as deformation and stress more sensitive to the runway surface material and the position of UAV, and the transverse deformation is sensitive to the runway surface material, but not to the internal pressure of the airbag.
Research on user requirements preprocessing of imaging reconnaissance satellites
Authors: Zhao Yulong , Zhang Yuan , Wang Yan , Pan Xianjun 
Published: July 2023

Abstract
Aiming at how to solve the problem of optimal matching between imaging reconnaissance user requirements and satellite resources, this paper conducts research on the preprocessing of imaging reconnaissance satellite requirements. First, considering the remote sensor type and resolution of imaging satellites, a requirement-resource matching matrix is constructed to realize the preliminary matching between user requirements and imaging reconnaissance satellite resources. Secondly, starting from the time constraints, by calculating the observation time window of requirement and resources, the time requirements of satellite resources and user requirements are matched. Finally, in order to solve the problem that the same observation task can be completed by multiple imaging satellites, a conflict resolution method based on resource consumption is proposed, which effectively improves the preprocessing ability of user requirements.
Minimum path deviation rapid online path planning of unmanned aerial vehicles with avoidance zones constraints
Authors: Liu Xin , Chai Pengfei , Cheng Peng , Han Jinkai , Wang Zeyuan 
Published: July 2023

Abstract
This paper investigates a minimum path deviation online path planning problem for UAV with constrainted avoidance zones. The nonlinear and nonconvex of this problem make the path planning is very time consuming and not acceptable for using onboard. Three new state variables and two control variables are redefined to convert the nonconvex problem into a second-order cone convex programming problem, which can be solved in polynomial time by primal-dual interior-point method, theoretical proof demonstrates the equivalence of the relaxed convex problem and the original problem. We propose a sequential second-order cone programming algorithm in order to get the optimal solution of the convexified problem. Numerical simulations show the effectiveness and less time-consuming of the proposed algorithm, no initial guess required and efficient solving process indicate that the algorithm has potential future for online path planning applications.
Load calibration experiment analysis for scaled model of large aspect ratio wing
Authors: Sun Qiaozhen , Zhang Bocheng , Yuan Haoqian 
Published: July 2023

Abstract
Load calibration experiment is the key work for flight load verification and flight test of civil aircraft. The efficiency of the flight load verification is meaningfully determined by the reliability of load calibration experiment. This paper aims to theoretically and experimentally study the load calibration of civil aircraft wing with large aspect ratio and elastic beam based on the scaled model, which includes the design of fixed device for wing loading, the data processing, the basic hypothesis test, the selection of regression variables and optimisation of regression equation, etc. Firstly, the systematic error is eliminated based on the sample difference method. Then, on the basis of the multiple linear regression method, the multi-collinearity among variables is weakened by using the multi-collinearity verification technology. Subsequently, the abnormal sample points are eliminated by the means of cyclic residual analysis. Finally, the optimized variables are screened with the method of the stepwise linear regression, and the load equations for the civil aircraft wing with large aspect ratio can be established. It is demonstrated that the calculated results verifies well with the engineering requirements by comparing with experimental results, and the error is smaller than 5%.
Optimal Landing Zone Selection and Online Trajectory Programming Method for Lunar Lander
Authors: Deng Yanpeng , Mu Rongjun , Wu Peng 
Published: July 2023

Abstract
To achieve a safe landing on the lunar surface with complex terrain, online landing zone selection is required. A DEM-based landing zone selection technique is proposed. The method firstly obtains several candidate landing zones by analyzing the gradient and variance information from the DEM, and then selects the integrated candidate landing zone by the overlap ratio. Finally, the optimal trajectory programming is carried out with the current state of the lander as the initial value and each integrated candidate landing zone as the final position, and the optimal landing zone is selected by comparing the required fuel to each landing zone. Compared with the classical DEM-based online landing site selection technique, the proposed method does not perform terrain reconstruction, responds quickly, and achieves real-time performance, and it also reduces fuel consumption, provides residual fuel for the subsequent landing phase, and increases the reliability of the landing process. Simulation results show that the proposed method is able to select several candidate landing zones in complex terrain, meanwhile, it is capable of achieving the optimal trajectory programming with the target of these several candidate landing zones, and finally, the optimal landing zone is selected by comparing the fuel consumption of each path.
An apparatus for low-temperature measurement using a spherical acoustic resonator
Authors: Qin H L , Zhou G , Li Q 
Published: July 2023

Abstract
Acoustic Gas Thermometry (AGT) is one of the most accurate methods of measuring thermodynamic temperature. The principal work of this research is the design of the measurement platform of AGT with a Pulse tube refrigerator temperatures between 4.2∼20K. The static simulation of the spherical resonator are concluded. Stress checking and heat leakage analysis of the system are emphasized. The system will be experimental used in the future.
Caesium- and sodium-filled pressure controlled heat pipe at NRC
Authors: Dedyulin Sergey , Gotoh Masahiko 
Published: July 2023

Abstract
What if you could tune the temperature of the fixed point used to calibrate your thermometer continuously between the freezing points of zinc (692.677 K) and silver (1234.93 K) while maintaining the uniform temperature environment (±10 mK) along 20 cm zone for hours at a time and with an uncertainty approaching a fraction of a mK? We are aiming to do exactly that by using a set of caesium- and sodium-filled pressure controlled heat pipes previously established at NRC. The original pressure controlled heat pipe furnaces have been recommissioned with a number of changes to improve their function as a calibration by comparison apparatus. In particular, the new gas handling system capable of controlling the pressure within ±4 ppm was installed side by side with the previously reported one. In this paper, we show the temperature performance of legacy NRC caesium- and sodium-filled pressure controlled heat pipes when connected to the new gas handling system.
Strain-enabled defect migration and defect activation in monolayer MoS2
Authors: Nechiyil Divya , Gokul M A , Shukla Ashutosh , Kumar G V Pavan , Rahman Atikur 
Published: July 2023

Abstract
Two-dimensional (2D) materials possess remarkable strain tolerance and exhibit strain-tunable properties, making them highly promising for flexible device applications. Defects within these materials significantly impact their optoelectronic response to strain. In this study, we investigate the influence of strain on the electrical properties of monolayer MoS2, emphasizing the pivotal role played by intrinsic defects in shaping the material’s electrical and optoelectronic response under strain. We observed an enhancement in photocurrent and persistent photoconductivity at specific strains, indicating the activation of defects at these strain values, thus enhancing the photoresponse. Moreover, our device exhibits diodic behavior at specific strain values after prolonged measurements under a static field, suggesting a reduction in the migration energy of defects caused by the applied strain. This finding holds significant implications for memory, logic, and flexible devices. Additionally, we observe an increase in electron mobility under tensile strain, with our flexible field-effect transistor exhibiting higher mobility (∼38 cm2 (V·s)−1) at 0.4% strain. Our study provides insight into the role of strain in the activation and migration of defects in monolayer MoS2 and opens up new avenues for the development of multifunctional ultra-thin flexible devices and memory applications.
Dissipation and irreversibility in computing
Authors: Ferry David K , Porod Wolfgang 
Published: July 2023

Abstract
There has been much discussion for decades over the proper concepts of minimum dissipation per logic gate and what is required for computation, as well as early arguments over logically reversible machines. Here these arguments, and the thermodynamics related to them, are discussed in terms of what is required for a computing machine. This gives a set of requirements for a valid computer that arise already from Turing and a set of limitations on energy dissipation and entropy. Here, the requirements set by Turing on what can and cannot be a computing machine are introduced, and how these limits affect not only the machine, but individual bits and a general need for irreversibility, are discussed. Then, it is shown that there is a minimum dissipation for a bit operation, and this is imposed both by Turing’s requirements as well as by noise in the system. Finally, it is shown that information entropy differs from physical entropy and care must be taken in trying to connect the two quantities. How these requirements, and new ones, affect quantum computation is also discussed.
Fast kernel methods for data quality monitoring as a goodness-of-fit test
Authors: Grosso Gaia , Lai Nicolò , Letizia Marco , Pazzini Jacopo , Rando Marco , Rosasco Lorenzo , Wulzer Andrea , Zanetti Marco 
Published: July 2023

Abstract
We propose an accurate and efficient machine learning approach for monitoring particle detectors in real-time. The goal is to assess the compatibility of incoming experimental data with a reference dataset, characterising the data behaviour under normal circumstances, via a likelihood-ratio hypothesis test. The model is based on a modern implementation of kernel methods, nonparametric algorithms that can learn any continuous function given enough data. The resulting approach is efficient and agnostic to the type of anomaly that may be present in the data. Our study demonstrates the effectiveness of this strategy on multivariate data from drift tube chamber muon detectors.
Follicular development and ovary aging: single-cell studies
Authors: Zhao Hong , Wang Yifu , Yang Yihua 
Published: July 2023

Abstract
Follicular development is a critical process in reproductive biology that determines the number of oocytes and interacts with various cells within the follicle (such as oocytes, granulosa cells, cumulus cells, and theca cells), and plays a vital role in fertility and reproductive health because of the dogma of a limited number of oogonia. Dysregulation of follicular development can lead to infertility problems and other reproductive disorders. To explore the physiological and pathological mechanisms of follicular development, immunology-based methods, microarrays, and next-generation sequencing have traditionally been used for characterization at the tissue level. However, with the proliferation of single-cell techniques, research has uncovered unique molecular mechanisms in individual cells that have been masked by previous holistic analyses. In this review, we briefly summarize the achievements and limitations of traditional methods in the study of follicular development. Simultaneously, we focus on how to understand the physiological process of follicular development at the single-cell level and reveal the pathological mechanisms and relevant intervention targets. Moreover, we also delineate the limitations and application prospects of single-cell sequencing in follicular development research.
Mechanism of BLIMP1/TRIM66/COX2 in human decidua participates in parturition
Authors: Zhou Wei , Geng Huizhen , Huang Yihong , Shi Shaole , Wang Zilian , Wang Dongyu 
Published: July 2023

Abstract
The mechanism underlying the initiation of parturition remains unclear. Cyclooxygenase 2 and prostaglandins in decidual membrane tissue play an important role in the “parturition cascade.” With the advancement of gestation, the expression of the transcriptional suppressor B lymphocyte-induced maturation protein 1 in the decidual membrane gradually decreases. Through chromatin immunoprecipitation sequencing, we found that B lymphocyte-induced maturation protein 1 has a binding site in the distal intergenic of PTGS2(COX2). Tripartite motif-containing protein 66 is a chromatin-binding protein that usually performs transcriptional regulatory functions by “reading” histone modification sites in chromatin. In this study, tripartite motif-containing protein 66 exhibits the same trend of expression as B lymphocyte-induced maturation protein 1 in the decidua during gestation. Moreover, the co-immunoprecipitation assay revealed that tripartite motif-containing protein 66 combined with B lymphocyte-induced maturation protein 1. This finding indicated that tripartite motif-containing protein 66 formed a transcription complex with B lymphocyte-induced maturation protein 1, which coregulated the expression of COX2. In animal experiments, we injected si-Blimp1 adenoviruses (si-Blimp1), Blimp1 overexpression plasmid (Blimp1-OE), and Trim66 overexpression plasmid (Trim66-OE) through the tail vein of mice. The results showed that B lymphocyte-induced maturation protein 1 and tripartite motif-containing protein 66 affected the initiation of parturition in mice. Therefore, the present evidence suggests that B lymphocyte-induced maturation protein 1 and tripartite motif-containing protein 66 partially participate in the initiation of labor, which may provide a new perspective for exploring the mechanism of term labor.
Primary care blood tests show lipid profile changes in pre-symptomatic amyotrophic lateral sclerosis
Authors: Thompson Alexander G , Marsden Rachael , Talbot Kevin , Turner Martin R 
Published: July 2023

Abstract
Multiple sources of evidence suggest that changes in metabolism may precede the onset of motor symptoms in amyotrophic lateral sclerosis. This study aimed to seek evidence for alterations in the levels of blood indices collected routinely in the primary care setting prior to the onset of motor symptoms in amyotrophic lateral sclerosis. Premorbid data, measured as part of routine health screening, for total cholesterol, high-density and low-density lipoprotein cholesterol, triglyceride, glycated haemoglobin A1c and creatinine were collected retrospectively from (i) a cohort of amyotrophic lateral sclerosis patients attending a specialist clinic (n = 143) and (ii) from primary care–linked data within UK Biobank. Data were fitted using linear mixed effects models with linear b-splines to identify inflection points, controlling for age and sex. In specialist amyotrophic lateral sclerosis clinic cases, models indicated decreasing levels of total and low-density lipoprotein cholesterol prior to an inflection point in the years before symptom onset (total cholesterol 3.25 years, low-density lipoprotein cholesterol 1.25 years), after which they stabilized or rose. A similar pattern was observed in amyotrophic lateral sclerosis cases within UK Biobank, occurring several years prior to diagnosis (total cholesterol 7 years, low-density lipoprotein cholesterol 7.25 years), differing significantly from matched controls. High-density lipoprotein cholesterol followed a similar pattern but was less robust to sensitivity analyses. Levels of triglyceride remained stable throughout. Glycated haemoglobin temporal profiles were not consistent between the clinic and biobank cohorts. Creatinine level trajectories prior to amyotrophic lateral sclerosis did not differ significantly from controls but decreased significantly in the symptomatic period after an inflection point of 0.25 years after symptom onset (clinic cohort) or 0.5 years before diagnosis (UK Biobank). These data provide further evidence for a pre-symptomatic period of dynamic metabolic change in amyotrophic lateral sclerosis, consistently associated with alterations in blood cholesterols. Such changes may ultimately contribute to biomarkers applicable to population screening and for pathways guiding the targeting of preventative therapy.
Development and Validation of a SPE–HPLC Method for Quantification of Rhein, Emodin, Chrysophanol and Physcion in Rhamnus petiolaris Boiss. & Balansa
Authors: Köseoğlu Yılmaz Pelin , Kolak Ufuk 
Published: July 2023

Abstract
Anthraquinones exhibit a significant group of natural and synthetic quinone derivatives because of their biological activities and industrial applications. Rhamnaceae is one of the families known to contain different kinds of anthraquinones. In this study, it was aimed to quantify rhein, emodin, chrysophanol and physcion in fruits of Rhamnus petiolaris Boiss. & Balansa belonging to Rhamnaceae by solid phase extraction and high performance liquid chromatography with ultraviolet detection. The anthraquinones were separated using a C18 analytical column. Gradient elution was performed using a mobile phase consisted of 0.1% o-phosphoric acid solution and methanol. Analytes were detected at 254 nm. Calibration curves were prepared in the range of 0.25–5.00 μg/mL for rhein, chrysophanol, physcion, 1.00–50.00 μg/mL for emodin. Limits of detection and quantification were between 0.07–0.11 and 0.20–0.34 μg/mL, respectively. Relative standard deviations were ≤ 5.78% in repeatability and intermediate precision studies. Accuracy was determined as relative mean error (8.17–12.06%). Extraction was achieved by maceration with acetone and ethanol, followed by hydrophilic–lipophilic balance solid phase extraction. Recoveries were between 96.2 and 109.6%. The developed and validated method was successfully performed to quantify rhein, emodin, chrysophanol and physcion in R. petiolaris fruit extracts. Only physcion was not detected above limit of detection.
Degrees of Comment on Keynes on Uncertainty: Review Article on Keynes on Uncertainty and Tragic Happiness: Complexity and Expectations by Anna M. Carabelli
Authors: Meeks J Gay 
Published: July 2023

Abstract
Oscar Wilde suggests that a book on which critics are agreed must be a ‘very obvious and shallow production’. This review article on Anna Carabelli’s 2021 book (a volume which helpfully draws together the fruits of her more than forty years’ research into Keynes’s method and ways of thought) involves five books that seem to invite the critical dissent that Wilde would have applauded. In her book, Carabelli displays her customary scholarship in writing about Keynes himself but is briskly dismissive of almost all commentators on his treatment of uncertainty and method. In what may be termed a fourth degree of comment - commenting on her comments on others’ comments on Keynes - I take issue with some of her attacks, especially over the extent to which Keynes regarded convention as a stabilising factor and over whether Keynes is misinterpreted by ‘followers of Hume’. A puzzle Carabelli seems to miss concerns which Hume is leading these ‘followers’ – in terms of current controversy, the ‘old’, the ‘new’ or perhaps yet another Hume. The nature of Hume’s own response to his famous sceptical challenge to inductive reasoning is in dispute, and it is contentious which of his two major works better shows this. Also subject to fierce debate is the relation of the philosophy in Keynes’s 1921 Treatise on Probability to the economics in his 1936 General Theory. Carabelli’s detailed history of thought perspective on how Keynes’s ideas grew encounters both rival historical slants and comment from a more purely analytical angle.
Aortic valve calcification is promoted by interleukin-8 and restricted through antagonizing CXC motif chemokine receptor 2
Authors: Dhayni Kawthar , Chabry Yuthiline , Hénaut Lucie , Avondo Carine , Boudot Cedric , Ouled-Haddou Hakim , Bigot-Corbel Edith , Touati Gilles , Caus Thierry , Messaoudi Hind , Bellien Jérémy , Tribouilloy Christophe , Messika-Zeitoun David , Zibara Kazem , Kamel Saïd , Bennis Youssef 
Published: July 2023

Abstract

Aims
Inflammatory cytokines play a critical role in the progression of calcific aortic valve disease (CAVD), for which there is currently no pharmacological treatment. The aim of this study was to test the hypothesis that interleukin-8 (IL-8), known to be involved in arterial calcification, also promotes aortic valve calcification (AVC) and to evaluate whether pharmacologically blocking the IL-8 receptor, CXC motif chemokine receptor 2 (CXCR2), could be effective in preventing AVC progression.

Methods and results
A cohort of 195 patients (median age 73, 74% men) diagnosed with aortic valve stenosis (severe in 16.9% of cases) were prospectively followed by CT for a median time of 2.6 years. A Cox proportional hazards regression analysis indicated that baseline IL-8 serum concentrations were associated with rapid progression of AVC, defined as an annualized change in the calcification score by CT ≥ 110 AU/year, after adjustment for age, gender, bicuspid anatomy, and baseline disease severity. In vitro, exposure of primary human aortic valvular interstitial cells (hVICs) to 15 pg/mL IL-8 induced a two-fold increase in inorganic phosphate (Pi)-induced calcification. IL-8 promoted NFκB pathway activation, MMP-12 expression, and elastin degradation in hVICs exposed to Pi. These effects were prevented by SCH527123, an antagonist of CXCR2. The expression of CXCR2 was confirmed in hVICs and samples of aortic valves isolated from patients with CAVD, in which the receptor was mainly found in calcified areas, along with MMP-12 and a degraded form of elastin. Finally, in a rat model of chronic kidney disease-associated CAVD, SCH527123 treatment (1 mg/kg/day given orally for 11 weeks) limited the decrease in aortic cusp separation, the increase in maximal velocity of the transaortic jet, and the increase in aortic mean pressure gradient measured by echocardiography, effects that were associated with a reduction in hydroxyapatite deposition and MMP-12 expression in the aortic valves.

Conclusion
Overall, these results highlight, for the first time, a significant role for IL-8 in the progression of CAVD by promoting calcification via a CXCR2- and MMP-12-dependent mechanism that leads to elastin degradation, and identify CXCR2 as a promising therapeutic target for the treatment of CAVD.