bluuebunny/crossref_metadata_2025_split huggingface dataset:
Early postoperative multiple intra-axial dissemination of a pediatric primary osteolytic extradural and complicated hydatid cyst
Authors: Borni Mehdi , Souissi Ghassen , Taallah Marouen , Abdelmouleh Souhir , Ayadi Ali , Boudawara Mohamed Zaher 
Published: June 2023

Abstract
Hydatid disease is very common around the Mediterranean basin and endemic in some parts of the world. Cerebral involvement remains rare, represents only about 2% of all hydatid localizations and mainly affects the pediatric population. Extradural hydatid cyst is very rare or even exceptional when it is associated with or followed by intracerebral disseminations. Here, the authors report a new exceptional case of an early multiple intra-axial hydatid dissemination in a 5-year-old North African male patient from a rural governorate who underwent surgery 3 months ago for a primary osteolytic extradural and complicated hydatid cyst with good clinical and radiological outcomes.
Examining Social Determinants of Health and Postpartum Outcomes of Adolescent Mothers in Monterrey, Nuevo León
Authors: Jimenez Andrea , Martinez Lisset , Carrasco-Magallanes Hector , Sarabia-Rabanales Valeria , Gonzalez-Oropeza Diego , Nava-Guerrero Eduardo , Cisneros-Rivera Fidel 
Published: June 2023

Abstract
Teenage pregnancy poses significant challenges for young women and their children, particularly in developing countries. This study examined the social determinants of health (SDoH) associated with teenage pregnancy and explored postpartum outcomes, including contraceptive use, education, job prospects, and repeat pregnancies. A cross-sectional study was conducted at a tertiary care center in Monterrey, Mexico, with a follow-up survey administered three years later.
The initial sample included 228 adolescents (<19 years old) receiving obstetric or prenatal care at the hospital. Socioeconomic factors such as poverty, unfavorable neighborhood conditions, and low parental education were prevalent among participants. While most intended to continue their education after childbirth, at the beginning of the study only 51% were still enrolled in school. The time span between sexual activity and the first pregnancy was short, indicating early sexual initiation.
Although most participants were aware of contraceptive methods, 27% reported never using contraception. School-based sex education was the primary source of information but lacked comprehensive coverage. Moreover, 44% did not plan to become mothers, highlighting the need for improved access to safe abortions and comprehensive sexual education. In the follow-up survey, 33% experienced repeat pregnancies within three years. Contraception issues, financial dependency, and limited access to contraceptive services contributed to unintended pregnancies.
Addressing social, economic, and cultural factors is crucial in reducing teenage pregnancy rates. Comprehensive sex education programs should cover diverse topics such as sexual diversity, healthy relationships, and violence prevention. Additionally, expanding access to safe abortion services and improving contraceptive counseling is vital. Targeted interventions are needed to challenge societal beliefs and cultural factors surrounding teenage pregnancy. By addressing these determinants and providing comprehensive reproductive health services, policymakers and healthcare providers can enhance the well-being and future prospects of young women affected by teenage pregnancy.
Perceptions and experiences of fertility preservation in Greek female cancer patients
Authors: Taniskidou Anna-Maria , Voultsos Polychronis , Tarlatzis Vasileios , Timotheadou Eleni 
Published: June 2023

Abstract
Background
As advances in oncology have led to remarkable and steady improvements in the survival rates of cancer patients and anticancer treatment can cause premature ovarian failure in women, fertility preservation has become a global public health concern and an integral part of the care for women diagnosed with cancer during reproductive age. However, for various reasons, fertility preservation remains underutilized for cancer patients. There are substantial gaps in our knowledge about women’s experience and perceptions on the issue. This study aims to contribute to bridging that gap.
Methods
This prospective qualitative study was conducted from March 2018 to February 2023. A combination of purposive and snowball sampling was used. Data were collected by semi-structured interviews with nineteen reproductive-age women with a recent cancer diagnosis. Data were classified and analyzed by a thematic analysis approach.
Results
A variety of distinct themes and subthemes emerged from the analysis of the interview data. The cancer diagnosis emerged as a factor that considerably affects the women’s attitudes towards biological parenthood: It can further increase their (strong) previous desire or decrease their previous (weak) desire. Women with a recent cancer diagnosis did not receive adequate and multidisciplinary counselling, including clear and sufficient information. However, participants felt satisfied from the information they received because they either received the information they requested or remained in denial to get informed (i.e. because they felt overwhelmed after the cancer diagnosis). Embryo cryopreservation emerged as a less desirable fertility preservation option for women with cancer. Participants showed respect for human embryos, not always for religious reasons. Surrogacy emerged as the last resort for most participants. Religious, social or financial factors did play a secondary (if any) role in women’s decision making about fertility preservation. Finally, male partners’ opinions played a secondary role in most participants’ decision-making about fertility preservation. If embryo cryopreservation was the selected option, partners would have a say because they were involved with their genetic material.
Conclusions
The findings that emerged from data analysis were partly consistent with prior literature. However, we identified some interesting nuances that are of clinical importance. The results of this study may serve as a starting point for future research.
Relationship between rheological properties of rice flour paste and printability of 3D food printer
Authors: Kamata Tatsuki , Nei Daisuke 
Published: June 2023

Abstract
3D food printers(3DFPs) are attracting interest due to the potential to create a new type of personalized food, and rice flour has the potential to be used in 3DFPs as a gluten-free carbohydrate food.
Rice flour with various properties and different moisture pastes were prepared and extruded from a 3DFP.
For all types of rice flour, it was found that paste with a high flow stress value(higher than 2303 Pa) could not be extruded from the nozzle and that paste with a low flow stress value(lower than 40 Pa) could not retain its shape after extrusion.
Weak gel model analysis of rice flour pulverized by a dry jet mill showed an unchanging and high coordination number, which appeared to be related to the shape stability.
The relationship between the rice flour paste and printability can be explained by rheological measurement results and the paste character can be controlled by changing the pulverization method and water addition amount.
Modified Posterior Osteotomy for Osteoporotic Vertebral Collapse with Neurological Dysfunction in Thoracolumbar Spine：a Preliminary Study
Authors: Long Zhisheng , Gong Feipeng , Xiong Long , Wen Jiabing , Chen Gang 
Published: June 2023

Abstract

Objective:The risk of Osteoporotic Vertebral Collapse(OVC) associated with delayed neurological dysfunction(DND) is high, and surgery for it in the elderly is challenging. How to simplify surgical procedures while preserving surgical efficacy has become a hot topic in treatment. This study aims to provide clinical data to support the advancement of modified posterior osteotomy for the treatment of thoracolumbar OVC with DND by comparing perioperative clinical parameters, imaging data characteristics and changes in efficacy outcome indicators.Methods:12 patients were diagnosed for Osteoporotic Vertebral Collapse in combination with neurological dysfunction. Modified Posterior osteotomy in all patients were designed. The perioperative, and radiological parameters and complications, including surgery duration, blood loss, ASIA grade,VAS, ODI, Regional Kyphosis Angle(RKA), Anterior Vertebral Height ratio(AVHr), Spinal Canal Invasion ratio(SCIr) , were collected retrospectively and analyzed to evaluate the clinical efficacy and safety of this technique.Results:Of the12 patients, Mean age: 65.50 ± 9.70 years, mean follow-up: 29.42 ± 4.98 months, mean operative blood loss: 483.33 ± 141.96 ml, mean operative time: 3.71 ± 0.66 hours, VAS score decreased from preoperative 5.83 ± 0.72 to final follow-up 1.25 ± 0.75 (P<0.05). Post-operative ODI reduced to 31.46%, and postoperative neurological function was significantly improved. The RKA was corrected from 35.8±10.83° to 20.03±3.54° after surgery and to 22.47±3.08° at final follow-up; AVHr% was corrected from 39.32±18.02 to 63.03±14.29 after surgery and to 53.89±8.94 at final follow-up; SCIr% was corrected from 54.88±5.41 to 68.13±5.30 after surgery and to 68.68±6.76 at final follow-up; Spinal canal volume immediately following surgery was increased by 24.14%.Conclusions:Posterior modified osteotomy is an effective treatment for thoracolumbar osteoporotic fractures with OVC combined with DND. It can significantly preserve vertebral height, increase vertebral canal volume, correct kyphotic angle, and improve postoperative neurological function. The simplified osteotomy also has certain advantages in terms of operating time, blood loss, postoperative VAS score and improvement in lumbar function.
Modified Blade: an Interventional Options in Rigid Bronchoscopy for Non-resectable Tracheal Stenosis
Authors: Messina Gaetana , Noro Antonio , Leone Francesco , Leonardi Beatrice , Grande Mario , Rainone Anna , Bove Mary , Opromolla Giorgia , De Gregorio Simona , Cerullo Giuseppe , Pirozzi Mario , Farese Stefano , Zotta Alessia , Natale Giovanni , Messina Giovanni , Vicidomini Giovanni , Fiorelli Alfonso , Ciardiello Fortunato , Fasano Morena 
Published: June 2023

Abstract
INTRODUCTION
Benign tracheobronchial stenosis is a abnormal tracheal lumen narrowing that may incur progressive dyspnea and life-threatening hypoxemia. There is no consensus on which patients should be treated with endoscopic or surgical method. This study investigates the outcomes bronchoscopic dilatation for treating benign tracheal stenosis using a device equipped with a blade to cut the stenotic lesions with dense fibrosis.
MATERIALS AND METHODS
The procedure was carried out in an operating room under general anesthesia. All patients were intubated with a Rigid Bronchoscope (RB) placed just above the stenosis. Through Rigid Bronchoscopy combined modalities were used as needed: radial incisions of the mucosal stenosis with blade at the levels of 4, 8 and 12 o’clock, with back and forth movements, then the stenotic area was dilated more easily with a rigid bronchoscope. Dilatation was performed by passing the RB through stenotic areas of increasing diameter and then Balloon dilation of increasing diameter. There were no complications during the procedure.
RESULT
We conducted an observational, retrospective, single-centre study in the Thoracic Surgery Unit of the University of ‘Luigi Vanvitelli’ of Naples from November 2011 to December 2022. We included all consecutive patients with benign tracheal stenosis inoperable. During the study period, 113 patients were referred to our department with benign tracheal stenosis inoperable. 61 patients were treated with the blade. During the follow-up, a recurrence of the stenosis was observed in 8 patients in the first month and in 4 patients in the third month. Instead in the patients treated with the use of laser (59 patients), during the follow-up a recurrence was observed in 16 patients in the first month and in 6 patients in the third month; no patient relapsed after 6 months and after 1 year. Long term successful bronchoscopic management with blade was attained by 99 % in simple and 93% in mixed stenosis and in complex type stenosis.
CONCLUSION
Our study underlines the importance of the use of the blade in bronchoscopic treatment as a valid conservative approach in the management of patients with inoperable benign tracheal stenosis as an alternative to the use of the laser, reducing the abnormal inflammatory reaction in order to limit recurrences.
A Quality Driven Framework for Decomposing Legacy Monolith Applications to Microservice Architecture
Authors: Hasan Muhammad Hafiz , Osman Mohd Hafeez , Admodisastro Novia Indriaty , Muhammad Muhamad Sufri 
Published: June 2023

Abstract
Transforming monolith applications to microservice architecture is a common cloud migration strategy for businesses to accomplish cloud-native benefits. However, decomposing monolith applications is a challenging task that requires experience, skills, and dedication to initiate this process, and often, the migrated product quality is neglected. The lack of relevant guidelines on the design quality for distributed cloud environment architecture such as microservice further exacerbates this concern. We propose a quality-driven decomposition framework for migrating monolith applications to the cloud-native architecture. Our approach implies six activities in decomposing monolith applications from the source code to the microservice architecture. This framework supports various architectural design properties related to maintainability quality. Furthermore, this framework enhances the machine learning approach to enable automatic microservice identification, hence evaluating the design quality using a scoring-based approach. We use five applications to evaluate our approach, and the results show that our framework can provide insightful judgment to the designer regarding microservice design quality.
Outcome of Colorectal Robotic Surgery in Newly Established Robotic Surgery Center: A Case Series
Authors: Alkhamis Ahmed A , Soliman Diaa M , Alsadder Khaled A , Busalha Hashem M , Alrashed Ahmad S , Alshaban Bader H , Alsafran Salman K , Almazeedi Sulaiman M 
Published: June 2023

Abstract
Introduction
The robotic platform compared to laparoscopy has proven to have similar postoperative outcomes, however its adoption in the middle east has been slow and there is limited data regarding outcomes with its use in small newly established robotic colorectal programs. Our aim is to report our experience and outcomes of robotic colorectal surgery performed by fellowship-trained robotic colorectal surgeons and compare it to larger more experienced centers.
Methods
This is a retrospective review of prospectively collected data between 11/2021 to 03/2023 from Jaber Al Ahmad hospital, a tertiary health care referral center. The study cohort included 51 patients who had robotic colorectal surgery. The outcomes were overall morbidity, serious morbidity, mortality, conversion to open, length of hospital stay and the quality of oncological specimen.
Results
Of 51 robotic colorectal surgery, our overall morbidity was 31.4% (n = 16 patients). Only 9.8% (n = 5) had serious morbidity of which three required interventions under general anesthesia. Our median length of hospital stay was 6 days (IQR = 4), and we had no mortality. Of 17 proctectomies for rectal cancer, we had 88% complete total Mesorectal excision, 15 of them were R0 resections, and our median lymph node harvested was 14 (IQR = 7). All our colon cancer resection had R0 resection and median lymph nodes harvested was 21 (IQR = 4). We had two conversion to open and no mortality.
Conclusions
The morbidity, mortality, conversion rates, and pathological specimens’ quality in new small robotic colorectal programs led by fellowship trained robotic colorectal surgeons can achieve comparable results to larger more established programs.
WITHDRAWN: Planning Forest Recreation Services for Urban Dwellers With a Multi- Criteria Approach (a Case of Türkiye)
Authors: YILMAZ Murat , BUĞDAY Seda ERKAN 
Published: June 2023

Abstract
Due to its geography, Türkiye has recently been exposed to extensive refugee migration and hosts many refugees. In addition, like the rest of the world, it has faced the challenges of the Covid-19 pandemic. Alongside these unfavorable situations, life continues, and people's orientation toward the services offered by forests and the planning of services are becoming more and more important every day. For this reason, this study focused on recreation, which is one of the non-wood forest products and services offered in forests in Türkiye. The distribution of national parks, nature parks, and A-, B-, C-, and D-type recreation areas, which are recreational areas in forests, were evaluated by weighted overlay analysis at the provincial level in Türkiye, using criteria such as Gross Domestic Product GDP per capita, number of people per km2, population growth rate, ratio of forest area to overall area, and total forest recreation areas. As a result of the analysis, the provinces were divided into three priority categories. Considering Türkiye's national development policies, different approaches are presented to planners in this study regarding organizing the utilization of forest service’s according to changing needs by evaluating the changing characteristics of the society and the forest structure together.
Intravenous Amiodarone-induced Acute Liver Failure: A Case Report and
Literature Review
Authors: Bteich Yara , Hosri Jad , Nauphal Nagi , Ibrahim Nour 
Published: June 2023

Background:
Hepatotoxicity of amiodarone has long been described and consists mostly of mild and delayed onset elevation in liver function tests. Fulminant hepatitis, however, is much rarer and attributed to the parenteral administration of the drug. The mechanism of injury is yet to be understood, though multiple theories have been proposed. This case report aims at highlighting the importance of monitoring patients receiving intravenous amiodarone therapy to detect severe acute liver injury and showcase the appropriate management thereafter.

Case Description:
Our patient is a 79-year-old male who presented with epigastric pain that was crampy, intermittent, and aggravated upon exertion. His heart rate was 93 beats/min and cardiac auscultation revealed an irregular heart rhythm. His electrocardiogram revealed atrial fibrillation. He was given intravenous amiodarone with a total dose of 950 mg and developed acute liver failure with extremely elevated liver function tests 48 hours after initiating the drug. After discontinuation, liver function tests returned to baseline within 10 days and the patient was discharged home.

Conclusion:
Physicians should be aware of the potentially life-threatening complications, including severe acute liver injury, by closely monitoring liver function tests following the administration of the drug and immediately discontinuing therapy if toxicity was detected.
Structural Elucidation, In vitro and In silico Biological Evaluations of New
Fluorinated Chalcone Derivatives for Potential Antioxidant Activity
Authors: Rajasagaran Rineswary , Mohamad Arshad Ahmad Saifuddin , Azizi Juzaili , Mohd Nizar Siti Nabilla Aliya , Arshad Suhana 
Published: June 2023

Abstract:
The newly synthesized fluorinated chalcone derivatives are observed to possess antioxidant
potential. Two new fluorinated chalcone compounds were effectively synthesized using the Claisen-
Schmidt condensation reaction and were recrystallized using the slow evaporation method. The single
crystal structure of the compounds was determined and refined through the X-ray single crystal diffraction
method. All compounds were subjected to computational structural characterization and
Hirshfeld surface analysis. The compounds were then further characterized through the Ultravioletvisible
(UV-Vis) spectroscopic study. The chalcone derivatives were further analysed with biological
experimentation and simulation such as in vitro antioxidant (DPPH) assay, molecular docking and in
silico ADMET study. The crystal packing revealed that the molecules in the compounds were linked
together through the intermolecular C—H···O and C—H···π interactions. Hirshfeld surface analysis
validated the presence of intermolecular interactions in crystal packing. The UV-Vis spectroscopic
study revealed that the absorption wavelength of the compounds that range from 421.79 to 428.98 nm
was within the visible region with the energy gap value of 2.58 to 2.62 eV. The DPPH assay disclosed
weak antioxidant activity of both compounds (-31 to 20 %, 10000 μg/mL) compared to the standard
ascorbic acid (94.5 %, 50 μg/mL). The binding energy of the docked complex inside the target protein,
2CAG was within the range of -7.3 to -7.5 kcal/mol. In the silico model, SwissADME predicted
that the two compounds have overall good drug-like properties. Different substituents, more planar
configuration and high intramolecular interactions in the crystal packing played their role in increasing
the antioxidant activities, binding energy and drug likeliness of the synthesized compounds.
Characterization of a High-performance PCF-SPR Sensor for Biomedical
Applications
Authors: Pradhan Himansu Shekhar 
Published: June 2023

Background:
Surface plasmon resonance (SPR) based fibre optic sensors are becoming increasingly
popular in biomedical applications. However, the sensor performance is degraded because of
low sensitivity with inadequate detection accuracy and figure of merit.

Objectives:
The first objective of this study is to design a D-shaped photonic crystal fibre (PCF) using
COMSOL multiphysics. The second objective is to enhance the performance of the designed sensor in
terms of sensitivity and detection accuracy using single and dual metal layer structures. In addition, the
performance of the proposed sensor is compared with the existing one.

Methods:
In this study, the performance of the PCF-SPR sensor is improved using a D-shaped photonic
crystal fibre (PCF) and two metals as grating layers. The work in this paper is divided into two parts. In
the first part, the gold metal layer with optimized thickness is used to achieve good sensitivity. In the
second part, the combination of gold and silver dual metal layers with optimized thickness is used to
achieve good detection accuracy. Moreover, the performance of the proposed sensor is compared to other
published D-shaped PCF sensors.

Results:
The proposed D-shaped PCF-SPR sensor is designed and simulated using COMSOL multiphysics.
The results in terms of sensitivity (S) and detection accuracy (DA) are obtained using a single metal
layer and dual metal layers with optimum thickness. Moreover, the transmission coefficient and loss
curve have been calculated using different refractive indices of the material. In addition, the simulation
results are validated for cancer detection using the proposed sensor.

Conclusion:
An improvement of the D-shaped PCF sensor for cancer detection is presented in terms of S
and DA using single or dual metal layer structures and COMSOL multiphysics. In a single metal layer
structure, only gold is used as a grating layer, and the thickness of the grating layer is optimized for
achieving high sensitivity. Similarly, a combination of gold and silver is used as the grating layer in the
dual metal layer structure for achieving a high DA. Moreover, the obtained results of the proposed PCFSPR
sensor are compared with the published results and found that the proposed sensor can be used with
a high degree of S and DA for biomedical applications and also can be used in the bio-sensing field.