bluuebunny/crossref_metadata_2025_split huggingface dataset:
Una refundición moretiana de una comedia de Claramonte: El valiente justiciero y El rey don Pedro en Madrid
Authors: Castrillo Alaguero Javier 
Published: August 2023

AbstractAgustín Moreto is one of the most outstanding authors of our Golden Theatre, because he was, in addition to Calderón, the main exponent of a form of composition that, together with collaborative writing, constitutes one of the most common dramaturgical modalities among secular poets: the rewriting. In this sense, the dramatic production of Agustín Moreto includes numerous motifs and arguments that were already present in the previous theater, especially in that of Lope de Vega. However, he was not the only playwright whom he took as a model, because he also consulted works by authors such as Tirso de Molina, Mira de Amescua, Guillén de Castro or Andrés de Claramonte. This work presents a rewriting of Moreto, El valiente justiciero, which starts from a text by Andrés de Claramonte, El rey don Pedro en Madrid y el infanzón de Illescas. Throughout the article, the most prominent similarities and differences between both comedies will be analyzed and it will be shown that the technique used by Moreto in his rewritings is very similar regardless of who the author of the source comedy is.
An Integrated Modeling Approach for Vertical Gas Migration Along Leaking Wells Using a Compressible Two-Fluid Flow Model
Authors: Qiao Yangyang , Skadsem Hans Joakim , Evje Steinar 
Published: August 2023

AbstractGas migration behind casings can occur in wells where the annular cement barrier fails to provide adequate zonal isolation. A direct consequence of gas migration is annular pressure build-up at wellhead, referred to as sustained casing pressure (SCP). Current mathematical models for analyzing SCP normally assume gas migration along the cemented interval to be single-phase steady-state Darcy flow in the absence of gravity and use a drift-flux model for two-phase transport through the mud column above the cement. By design, such models do not account for the possible simultaneous flow of gas and liquid along the annulus cement or the impact of liquid saturation within the cemented intervals on the surface pressure build-up. We introduce a general compressible two-fluid model which is solved over the entire well using a newly developed numerical scheme. The model is first validated against field observations and used for a parametric study. Next, detailed studies are performed, and the results demonstrate that the surface pressure build-up depends on the location of cement intervals with low permeability, and the significance of two-phase co-current or counter-current flow of liquid and gas occurs along cement barriers that have an initial liquid saturation. As the magnitude of the frictional pressure gradient associated with counter-current of liquid and gas can be comparable to the relevant hydrostatic pressure gradient, two-phase flow effects can significantly impact the interpretation of the wellhead pressure build-up.
Is Metalinguistic Usage a Conversational Implicature?
Authors: Soria-Ruiz Andrés 
Published: August 2023

AbstractI argue against the view that metalinguistic usage is a form of conversational implicature. That view, suggested by Thomasson (Anal Philos 57(4):1-28, 2016) and Belleri (Philos Stud 174(9):2211–2226, 2017), has been most recently fleshed out by Mankowitz (Synthese 199:5603–5622, 2021). I provide two types of criticism to the implicature view. From an empirical point of view, metalinguistic usage differs in key respects from standard cases of conversational implicature. From a conceptual standpoint, I argue that the calculation algorithm provided by the implicature view makes undesirable predictions. Although my main objective is negative, I end the paper by sketching an alternative neo-Stalnakerian view of metalinguistic usage, that can be gathered from work by Barker (Linguist Philos 25(1):1–36, 2002; Inquiry 56(2–3):240–257, 2013) and others.
Modelling Stormwater Runoff Changes Induced by Ground-Mounted Photovoltaic Solar Parks: A Conceptualization in EPA-SWMM
Authors: Gullotta Aurora , Aschale Tagele Mossie , Peres David J. , Sciuto Guido , Cancelliere Antonino 
Published: August 2023

AbstractA modelling framework for the simulation of stormwater runoff in ground-mounted photovoltaic solar parks is proposed. Elements in the solar park and their mutual interactions during precipitation events are conceptualized in EPA-SWMM. We demonstrate the potential of the framework by exploring how different factors influence runoff formation. Specifically, we carry out simulations for different sizes of the installation, soil types and input hyetographs. We also show the effect of ground cover, by changing the surface roughness. Outflow discharge from the park is compared to that from a reference catchment to evaluate variations of peak flow and runoff volume. Results highlight no practical changes in runoff in the short term after installation. However, in the long term, modifications in soil cover may lead to some potential increase of runoff. For instance, increments of the peak flow from the solar park up to 21% and 35% are obtained for roughness coefficient reductions of 10% and 20%, respectively. The proposed modelling approach can be beneficial for studying hydrological impacts of solar parks and thus for planning measures for their mitigation.
Fatty Acid-Binding Protein 4 is Essential for the Inflammatory and Metabolic Response of Microglia to Lipopolysaccharide
Authors: Kagawa Yoshiteru , Low Yi Ling , Pyun Jae , Doglione Umberto , Short Jennifer L. , Pan Yijun , Nicolazzo Joseph A. 
Published: August 2023

AbstractProlonged activation of microglia leads to excessive release of proinflammatory mediators, which are detrimental to brain health. Therefore, there are significant efforts to identify pathways mediating microglial activation. Recent studies have demonstrated that fatty acid-binding protein 4 (FABP4), a lipid binding protein, is a critical player in macrophage–mediated inflammation. Given that we have previously identified FABP4 in microglia, the aim of this study was to assess whether FABP4 activity contributed to inflammation, metabolism and immune function (i.e. immunometabolism) in immortalised mouse microglia (BV-2 cells) using the proinflammatory stimulus lipopolysaccharide (LPS) to induce general microglial activation. Microglial FABP4 expression was significantly increased following exposure to LPS, an outcome associated with a significant increase in microglial proliferation rate. LPS-stimulated BV-2 microglia demonstrated a significant increase in the production of reactive oxygen species (ROS) and tumour necrosis factor-alpha (TNF-α), phosphorylation of c-Jun N-terminal kinase (JNK), increased expression of Toll-like receptor 4 (TLR4), and reduced expression of uncoupling protein 2 (UCP2), all of which were reversed following FABP4 genetic silencing and chemical inhibition with BMS309403. The oxidation rate of 3H-oleic acid and microglial uptake of 3H-2-deoxy-D-glucose were modulated with LPS activation, processes which were restored with genetic and chemical inhibition of FABP4. This is the first study to report on the critical role of FABP4 in mediating the deleterious effects of LPS on microglial immunometabolism, suggesting that FABP4 may present as a novel therapeutic target to alleviate microglia-mediated neuroinflammation, a commonly reported factor in multiple neurodegenerative diseases.
Graphical Abstract
Does context matter? The gendered impact of study conditions on dropout intentions from higher education
Authors: Marczuk Anna , Strauss Susanne 
Published: August 2023

AbstractThis paper aims to understand how study conditions impact men and women’s dropout intentions differently. As a first step, we analyse the gendered impact of three aspects of study conditions that were at the centre of the Bologna Process: achievement norms, the structure of the curriculum and practical components in the study programme. As a second step, we aim to understand how individual-level differences between men and women (performance, academic self-efficacy and perceived psychological burdens) mediate this gendered impact of study conditions on dropout intentions. We use the German Student Survey data (2000–2016), which allows for valid measurement of study conditions at the subject group level. Our results show that women’s dropout intentions tend to increase in study contexts with high achievement norms, while men benefit more than women from highly structured study contexts. The practical component, in turn, lowers the dropout intentions of both groups equally.
Universal ontogenetic growth without fitted parameters: implications for life history invariants and population growth
Authors: Escala Andrés 
Published: August 2023

AbstractSince the work of von Bertalanffy (Q Rev Boil 32:217–231, 1957), several models have been proposed that relate the ontogenetic scaling of energy assimilation and metabolism to growth, which are able to describe ontogenetic growth trajectories for living organisms and collapse them onto a single universal curve (West et al. in Nature 413:628–631, 2001; Barnavar et al. in Nature 420:626, 2002). Nevertheless, all these ontogenetic growth models critically depend on fitting parameters and on the allometric scaling of the metabolic rate. Using a new metabolic rate relation (Escala in Theor Ecol 12(4):415–425, 2019) applied to a Bertalanffy-type ontogenetic growth equation, we find that ontogenetic growth can also be described by a universal growth curve for all studied species, but without the aid of any fitting parameters (i.e., no fitting procedure is performed on individual growth curves). We find that the inverse of the heart frequency $$\mathrm f_H$$

f
H

, rescaled by the ratio of the specific energies for biomass creation and metabolism, defines the characteristic timescale for ontogenetic growth. Moreover, our model also predicts a generation time and lifespan that explain the origin of several “Life History Invariants’ (Charnov in Oxford University Press, Oxford, 1993) and predict that the Malthusian parameter should be inversely proportional to both the generation time and lifespan, in agreement with the data in the literature (Duncan et al. in Ecology 88:324–333 2007; Dillingham et al. in Paper 535, 2016; Hatton et al. in PNAS 116(43):21616–21622 2019). In our formalism, several critical timescales and rates (lifespan, generation time, and intrinsic population growth rate) are all proportional to the heart frequency $$\mathrm f_H$$

f
H

, and thus, their allometric scaling relations come directly from the allometry of the heart frequency, which is typically $$\mathrm f_H \propto M^{-0.25}$$

f
H

∝

M

-
0.25

under basal conditions.
Mindfulness and financial well-being: multiple mediation of intrinsic career goals and work need satisfaction
Authors: Wu Xuan , Huang Shi-Zheng , Lakkanawanit Pankeawta 
Published: August 2023

AbstractThe goal of the current study is to investigate the relationship between mindfulness and financial well-being, for which the multiple mediating influences of intrinsic career goals and work need satisfaction are considered in combination with the self-determination theory. To verify the claimed association, a questionnaire study was conducted to gather information from 358 working adults in three under-developed regions of China. The results show that mindfulness positively influenced financial well-being. At the same time, intrinsic career goals and work need satisfaction act as parallel mediators between mindfulness and financial well-being. Nevertheless, the results don’t support the chained mediation from intrinsic career goals to work need satisfaction between mindfulness and financial well-being. Such findings offer insightful recommendations for enhancing financial well-being in the workplace through self-regulation of behaviours.
Charles Peirce’s Philosophy and the Intersection Between Biosemiotics and the Philosophy of Biology
Authors: Rodríguez Higuera Claudio 
Published: August 2023

AbstractCharles S. Peirce’s philosophy of signs, generally construed as the foundation of current semiotic theory, offers a theory of general perception with significant implications for the notion of subjectivity in organisms. In this article, we will discuss Peirce’s primary claims in semiotic theory, particularly focusing on their relevance to biosemiotics. We argue that these claims align with certain areas of the philosophy of biology, specifically epistemological and ontological considerations, despite the limited formal interaction between disciplines. This article serves as a general introduction to Peircean biosemiotics as a philosophical perspective on biological subjectivity.
Physiology of Stretch-Mediated Hypertrophy and Strength Increases: A Narrative Review
Authors: Warneke Konstantin , Lohmann Lars H. , Lima Camila D. , Hollander Karsten , Konrad Andreas , Zech Astrid , Nakamura Masatoshi , Wirth Klaus , Keiner Michael , Behm David G. 
Published: August 2023

AbstractIncreasing muscle strength and cross-sectional area is of crucial importance to improve or maintain physical function in musculoskeletal rehabilitation and sports performance. Decreases in muscular performance are experienced in phases of reduced physical activity or immobilization. These decrements highlight the need for alternative, easily accessible training regimens for a sedentary population to improve rehabilitation and injury prevention routines. Commonly, muscle hypertrophy and strength increases are associated with resistance training, typically performed in a training facility. Mechanical tension, which is usually induced with resistance machines and devices, is known to be an important factor that stimulates the underlying signaling pathways to enhance protein synthesis. Findings from animal studies suggest an alternative means to induce mechanical tension to enhance protein synthesis, and therefore muscle hypertrophy by inducing high-volume stretching. Thus, this narrative review discusses mechanical tension-induced physiological adaptations and their impact on muscle hypertrophy and strength gains. Furthermore, research addressing stretch-induced hypertrophy is critically analyzed. Derived from animal research, the stretching literature exploring the impact of static stretching on morphological and functional adaptations was reviewed and critically discussed. No studies have investigated the underlying physiological mechanisms in humans yet, and thus the underlying mechanisms remain speculative and must be discussed in the light of animal research. However, studies that reported functional and morphological increases in humans commonly used stretching durations of > 30 min per session of the plantar flexors, indicating the importance of high stretching volume, if the aim is to increase muscle mass and maximum strength. Therefore, the practical applicability seems limited to settings without access to resistance training (e.g., in an immobilized state at the start of rehabilitation), as resistance training seems to be more time efficient. Nevertheless, further research is needed to generate evidence in different human populations (athletes, sedentary individuals, and rehabilitation patients) and to quantify stretching intensity.
Multifunctional MXene/C Aerogels for Enhanced Microwave Absorption and Thermal Insulation
Authors: Wu Fushuo , Hu Peiying , Hu Feiyue , Tian Zhihua , Tang Jingwen , Zhang Peigen , Pan Long , Barsoum Michel W. , Cai Longzhu , Sun ZhengMing 
Published: August 2023

AbstractTwo-dimensional transition metal carbides and nitrides (MXene) have emerged as promising candidates for microwave absorption (MA) materials. However, they also have some drawbacks, such as poor impedance matching, high self-stacking tendency, and high density. To tackle these challenges, MXene nanosheets were incorporated into polyacrylonitrile (PAN) nanofibers and subsequently assembled into a three-dimensional (3D) network structure through PAN carbonization, yielding MXene/C aerogels. The 3D network effectively extends the path of microcurrent transmission, leading to enhanced conductive loss of electromagnetic (EM) waves. Moreover, the aerogel’s rich pore structure significantly improves the impedance matching while effectively reducing the density of the MXene-based absorbers. EM parameter analysis shows that the MXene/C aerogels exhibit a minimum reflection loss (RLmin) value of − 53.02 dB (f = 4.44 GHz, t = 3.8 mm), and an effective absorption bandwidth (EAB) of 5.3 GHz (t = 2.4 mm, 7.44–12.72 GHz). Radar cross-sectional (RCS) simulations were employed to assess the radar stealth effect of the aerogels, revealing that the maximum RCS reduction value of the perfect electric conductor covered by the MXene/C aerogel reaches 12.02 dB m2. In addition to the MA performance, the MXene/C aerogel also demonstrates good thermal insulation performance, and a 5-mm-thick aerogel can generate a temperature gradient of over 30 °C at 82 °C. This study provides a feasible design approach for creating lightweight, efficient, and multifunctional MXene-based MA materials.
Multi-fidelity and multi-objective aerodynamic short nacelle shape optimisation under different flight conditions
Authors: Tao G.C. , Wang W. , Ye Z.T. , Wang Y.N. , Luo J.Q. , Cui J.H. 
Published: August 2023

AbstractThroughout the course of a flight mission, a range of aerodynamic conditions, including design-point conditions and off-design conditions, are encountered. As the bypass ratio increases and the fan-pressure ratio decreases to reduce the engine’s specific fuel consumption, the engine diameters increase, which results in an increase in the nacelle weight and overall drag. To reduce its weight and drag, a shorter nacelle with a length-to-diameter ratio
$L/D = 0.35$
is investigated. In this study, an adaptive cokriging-based multi-objective optimisation method is applied to the design of a short aero-engine nacelle. Two nacelle performance metrics were employed as the objective functions for the optimisation routine. The cruise drag coefficient is evaluated under cruise conditions, whereas the intake pressure recovery is evaluated under takeoff conditions. The cokriging metamodel are refined using an effective infilling strategy, where high-fidelity samples are infilled via the modified Pareto fitness, and low-fidelity samples are infilled via the Pareto front. By combining parameterised geometry generation, automated mesh generation, numerical simulations, surrogate model construction, Pareto front exploration based on the non-dominated sorting genetic algorithm-II and sample infilling, an integrated multi-objective optimisation framework for short aero-engine nacelles is developed. Two-objective and three-objective test functions are used to validate the effectiveness of the proposed framework. After the optimisation process, a set of non-dominated nacelle designs is obtained with better aerodynamic performance than the original design, demonstrating the effectiveness of the optimisation framework. Compared with the kriging-based optimisation framework, the cokriging-based optimisation framework outperforms the single-fidelity method with a higher hypervolume value at the same number of iteration loops.
RNA N6-methyladenosine of DHAPAT and PAP involves in regulation of diapause of Bombyx mori via the lipid metabolism pathway
Authors: Chen Yan-Hua , Jiang Tao , Yasen Ayinuer , Fan Bing-Yan , Zhu Juan , Wang Mei-Xian , Shen Xing-Jia 
Published: August 2023

AbstractEnvironment-induced epigenetics are involved in diapause regulation, but the molecular mechanism that epigenetically couples nutrient metabolism to diapause regulation remains unclear. In this study, we paid special attention to the significant differences in the level of N6-adenosine methylation (m6A) of dihydroxyacetone phosphate acyltransferase (DHAPAT) and phosphatidate phosphatase (PAP) genes in the lipid metabolism pathway of the bivoltine silkworm (Bombyx mori) strain Qiufeng developed from eggs incubated at a normal temperature (QFHT, diapause egg producer) compared to those from eggs incubated at a low temperature (QFLT, non-diapause egg producer). We knocked down DHAPAT in the pupal stage of the QFLT group, resulting in the non-diapause destined eggs becoming diapausing eggs. In the PAP knockdown group, the colour of the non-diapause destined eggs changed from light yellow to pink 3 days after oviposition, but they hatched as normal. Moreover, we validated that YTHDF3 binds to m6A-modified DHAPAT and PAP mRNAs to promote their stability and translation. These results suggest that RNA m6A methylation participates in the diapause regulation of silkworm by changing the expression levels of DHAPAT and PAP and reveal that m6A epigenetic modification can be combined with a lipid metabolism signal pathway to participate in the regulation of insect diapause traits, which provides a clearer image for exploring the physiological basis of insect diapause.
Responses of soil–plant C, N, and P concentrations and stoichiometry to contrasting application rates of biochar to subtropical paddy field
Authors: Jin Qiang , Wang Weiqi , Song Xu , Sardans Jordi , Liu Xuyang , Lin Shaoying , Tariq Akash , Zeng Fanjiang , Peñuelas Josep 
Published: August 2023

Summary
Biochar is increasingly used in crop production as a fertilizer; however, its effects on nutrient cycling and stoichiometry in rice paddy soil–plant systems are unclear. We tested for effects of contrasting rates of biochar on soil and rice plant organ carbon (C), nitrogen (N), and phosphorus (P) concentrations and stoichiometry and soil physicochemical properties in early and late paddies. Overall, biochar reduced soil bulk density by an average of 7.4%, while application at 10, 20, and 40 t ha−1 increased soil C and N concentrations in early paddies by 31.6, 41.3, and 104.2%, respectively, and by 8.0, 5.0, and 21.8%, respectively; in late paddies, there were increases of 23.0, 94.1, and 117.0%, respectively, and 6.7, 15.4, and 18.0%, respectively (P < 0.05). Following biochar application at 10, 20, and 40 t ha−1, soil concentration of P decreased in early paddies by 10.9, 19.0, and 13.9%, respectively, and increased in late paddies by 4.3, 16.4, and 20.1%, respectively. Biochar increased ratios of soil C:N and C:P in early and late paddies (P < 0.05), and there was no effect on concentration and stoichiometry of soil available nutrients. Biochar reduced rice plant organ concentration of N and P in early rice and increased leaf N:P ratios. Despite the biochar application improved nutrient status in plant–soil system, we did not observe a significant increase in yield (P > 0.05). According to the N:P value of leaves between treatments, it was found that biochar alleviated the current situation of N limitation in paddy fields during the mature period and transformed the N limitation of early rice into a joint limitation of N and P. These results show that the addition of biochar to subtropical paddy soils leads to a short-term reduction in soil bulk density and increases in soil C and N concentrations and soil fertility. Thus, biochar applied at optimal rates is likely to improve the sustainability of subtropical paddy rice production.