bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative study on the reasons for failure factors of sustaining operational improvement methodologies in manufacturing enterprises
Authors: Minh Nguyen Dat , Quyen Nguyen Thi Hanh 
Published: June 2023

PurposeThis study aims to present the results of a comparative study on the most key reasons for the failure of sustaining activities of operational improvement (OI) methodologies from the different types of manufacturing enterprises that located in Vietnam.Design/methodology/approachThis study presents survey results from 30 local manufacturing enterprises and 21 foreign direct investment (FDI) enterprises located in Vietnam – a developing country. The authors utilize a combination method to collect data, including online and direct survey. The targeted interviewees selected to answer the questionnaire are manufacturing managers and top managers working in productivity, quality, engineering and other departments in respective firms. The developed questionnaire is verified by five experts to ensure the validity and soundness.FindingsThe study uncover that 21 local enterprises (70%) have not issued standard forms for OI deployment and supervision, while 17 foreign enterprises (81%) have adopted a systematic management and clearly indicators for evaluation of OI outputs. In addition, the top three reasons for OI failure are differences between local and foreign enterprises. In term of OI methodologies, most of participated enterprises implemented Lean tools and principles while only 7.8% of the participated enterprises applied Six Sigma. Three vital findings are uncovered, including, first, 30% of local enterprises standardize and supervise forms of OI.Research limitations/implicationsThere is a limitation in sample size, with the number of participants of 51 enterprises. Among the participants, 27% of local enterprises are small and medium-sized enterprises (SMEs) while 60% of FDI enterprises from large-sized group. This was limited to making a generated conclusion in the comparison of failure factors between two types of enterprises. This partly affects the radical comparison of failure factors between local and FDI enterprises.Originality/valueTo the best of the authors' view, this is the first empirical study that compares the reasons for the failure for sustaining OI between local and foreign enterprises in a developing country. The result from this study will make contributions for further research in considering OI failure factors and then enhance effectiveness of OI methodologies in manufacturing companies.
Impacts of enterprise zones on local households in Vietnam
Authors: Vu Tien Manh , Yamada Hiroyuki 
Published: June 2023

AbstractWe examine the possible impacts of enterprise zones (EZs) on local Vietnamese households between 2002 and 2008, using differences‐in‐differences and a panel‐event study. We layer four waves of household surveys using a census of EZs in 2007, based on the same commune identity for our household and individual analyses. Within 5 years of EZ establishment, we find they are associated with higher household incomes, an increase in private property prices, and an increase in working hours. However, we do not find a significant impact on household living expenditure or school attendance/working probabilities among members aged between 7 and 17 years. Neither do we find a significant impact on health outcomes.
An interlaboratory study to evaluate the utility of gas chromatography‐mass spectrometry and gas chromatography‐infrared spectroscopy spectral libraries in the forensic analysis of fentanyl‐related substances
Authors: Ferguson Kimiko , Perr Jeannette , Tupik Sherri , Gilbert Michael , Newman Reta , Winokur Agnes , Vallejo Ivette , Hokanson Stephen , Pothier Matthew , Knapp Brook , Icard Misty , Kramer Kevin , Almirall Jose 
Published: June 2023

AbstractSynthetic opioids such as fentanyl account for over 71,000 of the approximately 107,000 overdose deaths reported in the United States in 2021. Fentanyl remains the fourth most identified drug by state and local forensic laboratories, and the second most identified drug by federal laboratories. The unambiguous identification of fentanyl‐related substances (FRS) is challenging due to the absence or low abundance of a molecular ion in a typical gas chromatography‐mass spectrometry (GC‐MS) analysis and due to a low number of fragment ions that are similar among the many potential isomers of FRS. This study describes the utility of a previously reported gas chromatography‐infrared (GC‐IR) library for the identification of FRS within a blind, interlaboratory study (ILS) involving seven forensic laboratories. Twenty FRS reference materials, including those with isomer pairs in the library, were selected based on either their presence in the NIST library and/or some similarity of the mass spectra information produced. The ILS participants were requested to use the Florida International University (FIU) GC‐MS and GC‐IR libraries supplied by FIU to search for matches to their unknown spectra generated from in‐house GC‐MS and GC‐IR analysis. The laboratories reported improvement in the positive identification of unknown FRS from ~75% using GC‐MS alone to 100% correct identification using GC‐IR analysis. One laboratory participant used solid phase IR analysis, which produced spectra incompatible with the vapor phase GC‐IR library to generate a good comparison spectrum. However, this improved when searched against a solid phase IR library.
Leachate Lithium Characteristics of Loess‐paleosol Sequences on the Chinese Loess Plateau and their Paleoclimatic Significance
Authors: JIA Peng , FU Chaofeng , HE Maoyong , LIU Junfeng , LIU Na , LI Yulong , YANG Kaiyuan 
Published: June 2023

AbstractThe geochemical components of the leachate from loess‐paleosol deposits can provide information about climate‐related post‐depositional processes. For example, leachate lithium ([Li]leachate) is a potential paleoclimate proxy because lithium is a typical lithophile element that is readily adsorbed by clay minerals during weathering and pedogenesis, and thus stratigraphic variations in [Li]leachate can reflect these processes. We investigated the [Li]leachate values of two loess‐paleosols profiles (the Luochuan and Weinan sections), on a north–south climatic gradient on the Chinese Loess Plateau. Independent paleoclimate information was provided by measurements of magnetic susceptibility, grain size, Rb/Sr ratios, and clay mineral content. During the last glacial‐interglacial period, [Li]leachate increased from 0.39 to 1.97 μg/g at Luochuan and from 0.67 to 2.45 μg/g at Weinan, mainly due to increasing pedogenesis. Based on these results we developed a conceptual model to explain the variations in [Li]leachate. Li+ within loess layers is mainly derived from dust input and the decomposition of primary minerals, influenced by the East Asian winter monsoon, while in paleosol layers Li+ is mainly derived from clay mineral adsorption during pedogenic processes, influenced by the East Asian summer monsoon.
Two New Species of Eretmophyllum (Ginkgoales) from the Jurassic of Eastern Siberia
Authors: FROLOV Andrey , MASHCHUK Irina 
Published: June 2023

AbstractTwo new species of Eretmophyllum Thomas are described from the lower (Toarcian) and upper (Aalenian) Prisayan Formation of the Irkutsk Basin, Eastern Siberia, Russia based on distinct morphological and cuticular features of the leaves that distinguish them from other species of the genus. Eretmophyllum polypapillosum sp. nov. is characterized by the presence of 2–3 papillae on the lower and upper epidermis of ordinary cells. Taphonomically, the leaf burials of E. polypapillosum sp. nov. indicate that it preferred mesophilic forests developed on river terraces and/or low watersheds. Eretmophyllum yershowskiensis sp. nov. is represented exclusively by leaf cuticles extracted by coal maceration, and it probably inhabited the low banks of peat bogs. The presence of the genus Eretmophyllum in the Early Jurassic of France and Eastern Siberia shows that it was already widespread in the territory of Eurasia, distributed from Western Europe to Eastern Siberia. This indicates the possible existence of Eretmophyllum species elsewhere in the Early Jurassic such as Central Asia and Northwest China.
IDEAcology: An interface to streamline and facilitate efficient, rigorous expert elicitation in ecology
Authors: Courtney Jones Stephanie K. , Geange Sonya R. , Hanea Anca , Camac James , Hemming Victoria , Doobov Ben , Leigh Andrea , Nicotra Adrienne B. 
Published: June 2023

AbstractHere, we demonstrate how IDEAcology aids in preparing for and implementing a structured expert elicitation using the IDEA protocol, an iterative quantitative expert elicitation framework.Expert judgement is used to inform decision‐making on environmental assessment and management when imminent decisions are required, and quantitative data are absent or uninformative. Structured elicitation protocols can help improve the final judgements derived from experts, but they can also be administratively heavy and time‐consuming, requiring manual collation of experts' estimates and rationales, construction and dissemination of summary plots for discussion and collating final estimates post‐discussion. These challenges highlight the need for a centralised portal that enables synchronous access by all contributors, real‐time structured facilitation of discussion, whether in person or online, and streamlined data management.To meet this need, we developed the IDEAcology interface (www.ideacology.com) to support data collation, summary, interactions and ultimately the deployment of structured expert elicitation using the IDEA protocol. The IDEAcology interface is designed to be a central portal for scientists and practitioners to easily implement structured expert elicitation projects, while also facilitating data management by providing a reliable and efficient way for elicitation managers to design and run an elicitation, and for experts to input, visualise and cross‐examine estimates.The key advantages that IDEAcology provides include an easy‐to‐use interface with synchronous access to a single platform, reducing logistic difficulties, facilitating transparent discussion, improving the accuracy of estimates, enabling fast and efficient reporting by providing analysis‐ready data outputs and lastly, flexibility in the types of elicitation questions that can be accommodated in the interface.
Sex differences in the subjective and reinforcing effects of smoked cannabis
Authors: Lake Stephanie , Haney Margaret , Cooper Ziva D. 
Published: June 2023

AbstractPreclinical studies have shown sex‐based differences in the reinforcing effects of cannabinoid 1 receptor agonists such as delta‐9‐tetrahydrocannabinol (THC). This study sought to test whether these sex differences translate to humans by assessing the subjective and reinforcing effects of smoked cannabis in male and female volunteers. We pooled data (n = 68; 55M, 13F) from two within‐subject randomized controlled trials of healthy, ≥weekly cannabis users comparing the subjective and reinforcing effects of smoked active (~25 mg THC) versus placebo cannabis (0‐mg THC). Subjective ratings of drug effects and mood were measured using visual analogue scales, and reinforcing effects were measured with a cannabis self‐administration task. Sex‐dependent outcomes were explored using generalized linear mixed models. Under active cannabis conditions, female participants reported greater reductions from baseline in cannabis craving and significantly higher cannabis‐specific ratings of strength, liking, willingness to take again and good effect, compared with males (interaction p < 0.05). Placebo and active cannabis were self‐administered by 22% and 36% of male participants, respectively, and by 15% and 54% of female participants, respectively. Receipt of active cannabis significantly increased likelihood of self‐administration (p = 0.011), but a sex difference was not detected (p = 0.176). Although females were more sensitive to certain positive subjective effects of active cannabis, they were not more likely than males to self‐administer it. These findings highlight the need to test sex differences as a primary objective in experimental studies and may shed light on accelerated trajectories from initiation to cannabis use disorder observed among women.
Lifestyle factors and incident functional disability among a rural ageing population in South Africa
Authors: Pengpid Supa , Peltzer Karl 
Published: June 2023

AbstractObjectiveThe study aimed to assess the relationship between lifestyle factors and incident functional disability in South Africa.MethodsLongitudinal data (N = 4113) from two consecutive waves in 2014/2015 and 2018/2019 in Agincourt, South Africa, were analysed.ResultsModerate sedentary behaviour (AOR: 1.84, 95% CI: 1.31–2.58) and being overweight (AOR: 1.61, 95% CI: 1.10–2.36) increased the odds of incident functional disability among men. Moderate and high sedentary behaviour (AOR: 1.83, 95% CI: 1.31, 2.57, and AOR: 1.83, 95% CI: 1.08–3.10) increased the odds, and frequent fruit intake (AOR: 0.41, 95% CI: 0.19–0.91) and moderate physical activity (AOR: 0.47, 95% CI: 0.30–0.75) decreased the odds of incident functional disability among women.ConclusionsSedentary behaviour and being overweight increased odds, and physical activity and frequent fruit intake decreased odds of incident functional disability among ageing men and/or women in South Africa.
Australian dermatologists' prescribing behaviours for male androgenetic alopecia
Authors: Willems Anneliese , Moussa Anthony , Sinclair Rodney 
Published: June 2023

AbstractAndrogenetic alopecia (AGA) is highly prevalent among Australian men and can have significant psychological impacts. Despite its prevalence, treatment options have traditionally been limited. In this study, we examined the current prescribing patterns of Australian dermatologists for male AGA.
Development and initial validation of the Multidimensional Empathy Scale for Adolescents
Authors: Jung Sujong , Kim Eunha 
Published: June 2023

AbstractAdolescence is a transitional phase in psychosocial development in which individuals learn to navigate their social worlds. The need to socialize, connect with, and empathize with others is especially pronounced in this phase. This study aimed to develop and validate a self‐report empathy measure for adolescents, the Multidimensional Empathy Scale for Adolescents (MESA). Based on the theories and research on empathy, we created 24 items to measure six dimensions of empathy (cognitive, affective, positive, negative, majority, and minority). The dimensional structure of the MESA was examined in two independent samples of adolescents. The hypothesized six‐factor model of the MESA showed a good fit for both samples. Reliability analyses demonstrated that the MESA had high internal consistency and test–retest reliability. Furthermore, the MESA showed high convergent, discriminant, and incremental validity, as indicated by positive correlations with existing measures of empathy, idiocentrism–allocentrism, and social interest scales. The MESA, as a unique measure of six types of empathy, can be a valuable tool to assist adolescents in developing a balanced sense of empathy.
Strategic generosity among local patrons: Place belonging and ethnic exclusion in a transforming lower‐income neighborhood of Tel Aviv
Authors: Shamur Tal 
Published: June 2023

AbstractWorking at the intersection of exchange theory, urban anthropology, and ethnic and racial studies, this article offers an original perspective on the role of local patrons’ exchange networks in constructing place belonging during racial urban change. Inspired by a middle‐ground approach to reciprocity, embodying both solidarity and distrust within the same ethnic community, and manifested in an interracial context, the article proposes the integrative term of strategic generosity. The concept includes two interlinked layers: the combination of altruism and self‐interest in local patrons’ exchange practices within the same ethnic community, and patron exchange circles as mechanisms for the exclusion of racial Others reproducing boundaries between social groups. The case study is HaTikva—a lower‐income neighborhood in downtown Tel Aviv originally inhabited almost exclusively by disadvantaged Mizrahi Jews (of Middle Eastern origin), and more recently transformed by the arrival of African asylum seekers. Based on fieldwork conducted from 2010 to 2013 among long‐term Mizrahi residents, I argue that although local Mizrahi patrons use parental metaphors to describe their unconditioned giving to their own community; in fact, altruist and instrumental actions intermingle in the management of their reciprocity network. The exchange networks help vulnerable agents and enhance Mizrahi place attachment, but at the same time buttress the patrons’ own standing in the neighborhood and exclude the non‐Jewish African Others. These findings are discussed in the context of everyday life in a marginalized ethnic community as well as a barrier to integration and the concept's contribution to exchange theory more broadly. [strategic generosity, ethnic exclusion, exchange theory, place belonging, Mizrahi Jews, Tel Aviv]
Cells of the renin lineage promote kidney regeneration post‐release of ureteral obstruction in neonatal mice
Authors: Nagalakshmi Vidya K. , Li Minghong , Liang Xiuyin , Medrano Silvia , Belyea Brian C. , Gomez R. Ariel , Sequeira‐Lopez Maria Luisa S. 
Published: June 2023

AbstractAimUreteral obstruction leads to significant changes in kidney renin expression. It is unclear whether those changes are responsible for the progression of kidney damage, repair, or regeneration. In the current study, we aimed to elucidate the contribution of renin‐producing cells (RPCs) and the cells of the renin lineage (CoRL) towards kidney damage and regeneration using a model of partial and reversible unilateral ureteral obstruction (pUUO) in neonatal mice.MethodsRenin cells are progenitors for other renal cell types collectively called CoRL. We labeled the CoRL with green fluorescent protein (GFP) using genetic approaches. We performed lineage tracing to analyze the changes in the distribution of CoRL during and after the release of obstruction. We also ablated the RPCs and CoRL by cell‐specific expression of Diphtheria Toxin Sub‐unit A (DTA). Finally, we evaluated the kidney damage and regeneration during and after the release of obstruction in the absence of CoRL.ResultsIn the obstructed kidneys, there was a 163% increase in the renin‐positive area and a remarkable increase in the distribution of GFP+CoRL. Relief of obstruction abrogated these changes. In addition, DTA‐expressing animals did not respond to pUUO with increased RPCs and CoRL. Moreover, reduction in CoRL significantly compromised the kidney's ability to recover from the damage after the release of obstruction.ConclusionsCoRL play a role in the regeneration of the kidneys post‐relief of obstruction.
Population pharmacokinetic/pharmacodynamic target attainment of ceftriaxone 2 g once daily in non‐critically ill hospitalized adult patients during the acute phase of infection
Authors: van den Broek Annemieke K. , van Schip Anne , Visser Caroline E. , Bos Jeannet C. , Prins Jan M. , van Hest Reinier M. 
Published: June 2023

AbstractAimsPharmacokinetic/pharmacodynamic target attainment of ceftriaxone is compromised in intensive care unit (ICU) patients and non‐ICU hospitalized patients in Beira, Mozambique. Whether this also accounts for non‐ICU patients in a high‐income setting is unknown. We therefore assessed the probability of target attainment (PTA) of the currently recommended dosing regimen of 2 g every 24 h (q24h) in this patient group.MethodsWe performed a multicentre population pharmacokinetic study in hospitalized non‐ICU adult patients empirically treated with intravenous ceftriaxone. During both the acute phase of infection (i.e. first 24 h of treatment) and convalescence, a maximum of 4 random blood samples were obtained per patient for ceftriaxone total and unbound concentration measurements. PTA was calculated using NONMEM and was defined as the percentage of patients of which the unbound ceftriaxone concentration exceeded the minimum inhibitory concentration (MIC) for >50% of the first dosing interval of 24 h. Monte Carlo simulations were performed to determine PTA for different estimated glomerular filtration rates (eGFR; CKD‐EPI) and MICs. PTA >90% was considered adequate.ResultsForty‐one patients provided 252 ceftriaxone total and 253 unbound concentrations. The median eGFR was 65 mL/min/1.73 m2 (5th to 95th percentile 36–122). With the recommended dose of 2 g q24h, PTA >90% was achieved for bacteria with an MIC ≤2 mg/L. Simulations showed that PTA was insufficient for an MIC of 4 mg/L in case the eGFR was 122 mL/min/1.73 m2 (PTA 56.9%) and for an MIC of 8 mg/L regardless of eGFR.ConclusionThe PTA of 2 g q24h ceftriaxone dosing is adequate for common pathogens during the acute phase of infection in non‐ICU patients.
Too hot to help or too cold to care? On the links between ambient temperature, volunteerism, and civic engagement
Authors: Ng Henry Kin Shing , Cheung Sing‐Hang 
Published: June 2023

AbstractWe investigated the relationship between ambient temperature and prosocial behaviour in real‐life settings. It was guided by two mechanisms of opposite predictions, namely (1) higher temperatures decrease prosociality by harming well‐being, and (2) higher temperatures increase prosociality by promoting the embodied cognition of social warmth. In Study 1, U.S. state‐level time‐series data (2002–2015) supported the first mechanism, with higher temperatures predicting lower volunteer rates through lower well‐being. Study 2 furthered the investigation by probing the relationship between neighbourhood temperature and civic engagement of 2268 U.S. citizens. The data partially supported the well‐being mechanism and reported findings contradictory to the social embodiment mechanism. Higher temperatures predicted lower interpersonal trust and subsequently lower civic engagement. The unexpected finding hinted at a cognitive effect of heat and a compensatory mechanism in social thermoregulation. We discussed the findings regarding their methodological strengths and weaknesses, with cautions made on ecological fallacies and alternative models.
Understanding the interaction between leukaemia stem cells and their microenvironment to improve therapeutic approaches
Authors: Martinez Leandro M. , Guzman Monica L. 
Published: June 2023

Although chemotherapeutic regimens can eliminate blasts in leukaemia patients, such therapies are associated with toxicity and often fail to eliminate all malignant cells resulting in disease relapse. Disease relapse has been attributed to the persistence of leukaemia cells in the bone marrow (BM) with the capacity to recapitulate disease; these cells are often referred to as leukaemia stem cells (LSCs). Although LSCs have distinct characteristics in terms of pathobiology and immunophenotype, they are still regulated by their interactions with the surrounding microenvironment. Thus, understanding the interaction between LSCs and their microenvironment is critical to identify effective therapies. To this end, there are numerous efforts to develop models to study such interactions. In this review, we will focus on the reciprocal interactions between LSCs and their milieu in the BM. Furthermore, we will highlight relevant therapies targeting these interactions and discuss some of the promising in vitro models designed to mimic such relationship.LINKED ARTICLESThis article is part of a themed issue on Cancer Microenvironment and Pharmacological Interventions. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v181.2/issuetoc