bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anti-PLA2R Antibody Levels and Clinical Risk Factors for Treatment Nonresponse in Membranous Nephropathy
Authors: Barbour Sean J. , Fervenza Fernando C. , Induruwage Dilshani , Brenchley Paul E. , Rovin Brad , Hladunewich Michelle A. , Reich Heather N. , Lafayette Richard , Aslam Nabeel , Appel Gerald B. , Zand Ladan , Kiryluk Krzysztof , Liu Lili , Cattran Daniel C. ,   for the MENTOR Trial Investigators
Published: July 2023

Background
The 2021 Kidney Disease Improving Global Outcomes (KDIGO) guidelines recommend following anti-phospholipase A2 receptor (PLA2R) antibody levels as a marker of treatment response in membranous nephropathy; however, the optimal timing to evaluate antibody levels and how to combine them with other clinical variables are currently unknown.

Methods
We used a cohort of 85 patients from the Membranous Nephropathy Trial Of Rituximab (MENTOR) with anti-PLA2R antibodies ≥14 RU/ml to identify risk factors for not experiencing proteinuria remission after 12 months of treatment with cyclosporine or rituximab. Three landmark times were considered: at baseline and after 3 and 6 months of treatment. Logistic regression model performance was evaluated using C-statistics and model fit (Akaike information criterion [AIC], R2).

Results
The model at baseline that best predicted no remission included anti-PLA2R antibodies >323 RU/ml and creatinine clearance; the best model after 3 months included the change from baseline in both antibody and albumin levels; and the best model after 6 months included antibody levels >14 RU/ml, creatinine clearance, and the change from baseline in albumin. Compared with the model at baseline, the model at 3 months had better model fit (AIC 70.9 versus 96.4, R2 51.8% versus 30.1%) and higher C-statistic (0.93 versus 0.83, P = 0.008). The model at 6 months had no difference in performance compared with the model at 3 months (AIC 68.6, R2 53.0%, C-statistic 0.94, P = 0.67).

Conclusions
In patients with membranous nephropathy treated with cyclosporine or rituximab in the MENTOR trial, we found that the optimal method to evaluate risk factors for the probability of treatment response was to use anti-PLA2R antibody levels combined with albumin levels after 3 months of treatment, which was significantly better than using antibody levels alone or risk factor evaluation at baseline, with no added benefit of waiting until 6 months of treatment.

Podcast
This article contains a podcast at https://dts.podtrac.com/redirect.mp3/www.asn-online.org/media/podcast/CJASN/2023_10_09_CJN0000000000000237.mp3
Pengaruh Status Gizi, Kesegaran Jasmani dan Motivasi Belajar terhadap Hasil Belajar PJOK
Authors: Furnandi Andi , Yudi Alex Aldha , Rifki Muahamad Sazeli , Syahrastani Syahrastani 
Published: July 2023

Penelitian ini bertujuan untuk menganalisis dampak dari status gizi dan kesegaran jasmani serta motivasi belajar sebagai faktor untama yang berpengaruh terhadap hasil belajar pendidikan jasmani. Pembelajaran afektif dilaporkan menjadi salah satu faktor kunci dalam pencapaian hasil belajar pendidikan jasmani. Fokus dalam penelitian ini pada faktor status gizi, kesegaran jasmani, motivasi dan belajar siswa. Kami melakukan survei kepada siswa dalam jumlah 41 orang. Kemudian memeriksa temuan menggunakan statistik deskriptif, dengan memanfaakan IBM SPSS software. Hasil menunjukkan bahwa, terdapat pengaruh secara lansung maupun tidak langsung dari prediktor statu gizi, kesegaran jasmani, dan motivasi belajar terhadap hasil belajar pendidikan jasmani. Kekuatan pengaruh langsung dan tidak langsung mengidentifikasi bahwa secara signifikan perpengaruh positif antara status gizi dan kesegaran jasmani melalui motivasi belajar terhadap hasil belajar PJOK Siswa SD Negeri 11 Silokek Kabupaten Sijunjung.
Analisis waktu penampilan pertandingan pencak silat kategori jurus tunggal pada kejuaraan virtual tingkat pra-remaja & remaja
Authors: Syura Yukta Terate , Rahayuni Kurniati , Taufik Taufik 
Published: July 2023

Masalah: Pencak silat memiliki kategori yang dipertandingkan salah satunya adalah jurus tunggal yang memperagakan 14 jurus yang dibagi menjadi 7 jurus tangan kosong, 3 jurus golok dan 4 jurus toya yang di peragakan selama 3 menit dan belum ada referensi waktu yang efektif untuk peragaannya.
Tujuan: Tujuan dari penelitian ini adalah untuk mengetahui efektifitas waktu yang tepat dalam penampilan jurus tunggal pada pra-remaja dan remaja. Kelebihan dan kekurangan peragaan dapat mempengaruhi nilai peserta dan juga berpengaruh terhadap performa atlet.
Metode: Penelitian ini menggunakan video visual di youtube dan mengambil 40 sampel yang terdiri dari beberapa atlet terbaik di kejuaraan seperti PORPROV, Kejuaraan Virtual Nasional, KEJURPROV Pelajar. Penelitian ini menggunakan analisis statistik deskriptif yaitu perhitungan mean, median, modus untuk mengetahui efektifitas gerakan guna mencapai ketepatan waktu 3 menit yang dicatat melalui excel.
Hasil: Penelitian ini memperoleh hasil tingkat pra-remaja memperagakan waktu rata-rata 2 menit 56 detik. Untuk tingkat remaja memperagakan waktu rata-rata 2 menit 59 detik. Perkiraan sistem energi yang ditemukan untuk jurus tunggal adalah anaerobic sebesar 77% dan aerobic sebesar 22%..
Kesimpulan: Maka dapat disimpulkan bahwa jenjang pra-remaja dan remaja harus diperhatikan dengan baik untuk ketepatan waktu, serta menyusun program latihan yang tepat. Hasil dan saran dari penelitian ini dapat digunakan sebagai referensi untuk mengidentifikasi energi dan membuat latihan yang terprogram sebagai acuan dalam memperagakan jurus jurus tunggal
Kata Kunci: pencak silat, jurus tunggal, durasi waktu
Pengaruh pembelajaran daring terhadap penurunan hasil belajar PJOK siswa SD pada masa pandemi covid-19
Authors: Saputra Peno Eka , Bafirman Bafirman 
Published: July 2023

Masalah: Permasalahan dalam penelitian ini adalah rendahnya hasil belajar PJOK siswa kelas V SDN 22 Ujung Gurun selama pembelajaran di masa pandemi COVID-19.
Tujuan: Penelitian ini bertujuan untuk mengetahui pengaruh pembelajaran daring terhadap penurunan hasil belajar PJOK siswa kelas V Sekolah Dasar Negeri 22 Ujung Gurun.
Metode: Metode penelitian yang digunakan adalah kuantitatif dengan menggunakan analisis jalur. Populasi dalam penelitian ini adalah seluruh siswa SDN 22 Ujung Gurun yang berjumlah 304 orang. Teknik pengambilan sampel dilakukan secara purposive sampling, dengan jumlah sampel 42 orang. Pengumpulan data dilakukan dengan mengamati dan mengisi angket pembelajaran daring. Selanjutnya untuk mengukur hasil belajar PJOK digunakan rata-rata nilai ulangan mingguan dari tanggal 12 Juli-9 Agustus 2021 (semester 1 tahun ajaran 2021/2022)
Hasil: Hasil penelitian dan analisis data menunjukkan bahwa pembelajaran daring berpengaruh terhadap penurunan hasil belajar PJOK sebesar 5,85%.
Kesimpulan: Para guru PJOK sebaiknya melakukan pembelajaran secara langsung karena akan memiliki efek terhadap peningkatan hasil belajar siswa.
Study of Best Practices of Green Energy Development in the EU Countries Based on Correlation and Bagatofactor Autoregressive Forecasting
Authors: Yelisieieva Oksana , Lyzhnyk Yuliya , Stolietova Iryna , Kutova Natalia 
Published: July 2023

Abstract
Russia’s military aggression against Ukraine has undermined the global energy system, leading to high energy prices and increased concerns about the EU’s energy security EU leaders have adopted a number of laws and developed the REPowerEU plan to reduce dependence on Russian energy imports by accelerating the transition to clean energy and creating a more sustainable energy system in Europe. The plan includes measures to save energy, diversify supplies and rapidly replace fossil fuels with clean energy sources, as well as prioritizes equity and solidarity, taking into account the energy balances of each EU member state. It builds on the Fit for 55 proposals and supports the ambitious goal of achieving at least -55% net greenhouse gas emissions by 2030 and climate neutrality by 2050.The aim of the article is to study the use of renewable energy in the European Union, the application of autoregressive models to predict the development of renewable energy.The results and conclusions. As a result of the study, based on the methodology of transients, a model of change in the volume of investment in wind energy was developed in the form of a differential equation. It was proved that the transition process is stable, even with time constraints or reduction of investment in the development of wind energy over time it will return to a stable growing trend (which was obtained by means of bagatofactor autoregressive models).
Evaluation of the Smart Cities Listed in Smart City Index 2021 by Using Entropy Based Copras and Aras Methodology
Authors: Gelmez Emel , Özceylan Eren 
Published: July 2023

Abstract
Smart cities are included in the literature as a technology-based concept that has been on the agenda in recent years and whose framework is constantly changing with the changes in technology. There are different frameworks and indexes to define the smartness of a city. Smart City Index 2021 published by Institute for Management Development (IMD) and Singapore University of Technology and Design (SUTD) is one of the accepted studies in the world. In the report of Smart City Index 2021, 118 cities are evaluated in five criteria namely health & safety, mobility, activities, opportunities (work & school) and governance. To re-evaluate the cities and compare the results, a Multi-Criteria Decision Making (MCDM) process including Entropy based Complex Proportional Assessment (COPRAS) and Addivite Ratio Assessment (ARAS) methodology is applied in this paper. To prioritize the criteria, entropy weight method is used. 118 cities are ranked both technologically and structurally using the COPRAS and ARAS method. As a result of the analyses, according to these methods, the rankings of the smart cities are the same. Also, when technologically smart cities are listed, it is determined that the first three countries are Zhuhai, Shenzhen, Nanjing, and at the same time, Abu Dhabi, Chongqing, Hangzhou in terms of structurally.
The Complexity of the Current operational Environment and the Military Leader'S Ability to Adapt to its Ongoing Challenges
Authors: Badiu Marius-Iulian , Țică Laura-Alexandra 
Published: July 2023

Abstract
The current operational environment is characterized by a high degree of complexity, uncertainty, and ambiguity. Military leaders must be able to adapt to these ongoing challenges in order to succeed in their missions and achieve their objectives. One of the key challenges facing military leaders in the current operational environment is the rapidly changing nature of the threats they face. These threats can come from a wide range of sources, including state and non-state actors, terrorist organizations, and cyber attacks. Additionally, the proliferation of advanced technologies has created new vulnerabilities that military leaders must be able to address. Another challenge facing military leaders is the need to operate in a highly networked and interconnected environment. This requires a deep understanding of the complex systems that underpin modern warfare, as well as the ability to coordinate and collaborate with a wide range of stakeholders across multiple domains. Overall, the complexity of the current operational environment requires military leaders to be highly skilled, adaptable, and flexible. By developing these skills and leveraging new technologies and approaches, they can successfully navigate the challenges they face and achieve their objectives.
Elements of Improving Operational Logistics Planning Specific to Combatant Forces
Authors: Minculete Gheorghe , Monoranu Radu 
Published: July 2023

Abstract
The challenges, threats and regional military actions not far from the borders of NATO's eastern flank has demonstrated and reveals the need to reconfigure the potential and provide adequate, timely and resilient logistical support to operational offers at the tactical and joint levels. In this paper we highlight some aspects of the improvement of operational logistics planning, taking into account some elements such as: particularities of focused logistics, typology of planning, planning-execution correlation, evaluation of planning implementation, new requirements resulting from the lessons identified from the war in Ukraine. All the sequences that will be developed in this communication will be adequately correlated; taking into account the military operations of the future that will be planned and carried out in a national and/or multinational context.
Military Actions Characteristics in Hybrid Operational Environments
Authors: Rațiu Aurelian , CÎrdei Alin , Herman Ramona 
Published: July 2023

Abstract
The theoretical approaches regarding the security/operational environment aimed at a multidimensional and integrative perspective, because its understanding requires not only analysis of the physical terrain, but also the perspective of the actors involved, and of the factors from the informational environment (including cyberspace) and those specific to the civilian population. The field of contemporary military confrontations is extremely difficult to analyze because of the dynamics of the phenomenon and internal processes, of the implemented technologies and, last but not least, as a result of the manifestation of VUCA (Volatility, Uncertainty, Complexity and Ambiguity) characteristics within them. But, the effort of scientific investigations was directed starting from the premise that the identification of the characteristics and of the factors specific to the future confrontational environment serves as a starting point in the approach of conceptual-doctrinal and operational adaptation/transformation of the military forces. An attempt was made to find the answer to the question: which are the conditions, circumstances and factors characteristic of the confrontational environment that influence the efficiency and coherence of the actions of the engaged capabilities?
Strategic Management in a Complex Geopolitical and Economic Context
Authors: Iancu Dumitru , Dinicu Anca 
Published: July 2023

Abstract
After the end of the COVID-19 pandemic, markets and economies were expected to stabilize in the sense of returning to average growth trends so that strategies and strategic management in organizations would be much more straightforward and predictable. Not only has the economic recovery not happened, with dramatic consequences, at least in terms of productivity, trade, and tourism, but developments on the international stage in the post-pandemic period, including the conflict in Ukraine, the failure of Silicon Valley Bank, Signature Bank, and First Republic Bank in the US, the takeover of Credit Suisse by UBS Bank in Switzerland, the social upheavals in France and Israel, do not support this stabilization, but on the contrary create fears of cascading events, contagion and widespread seizure of the international security environment. Thus, we consider the question: Is strategic management still relevant in a complex, fluid, and challenging context?
Landmines Between Banning and a Widespread Use
Authors: Andrei Constantin 
Published: July 2023

Abstract
The use of traps and landmines in military conflicts has its roots in antiquity. The evolution and continuous technological progress, recorded by humanity in all areas of economic and social life, had a special role in the development of new types of explosives with high destructive power, which in turn inevitably determined the diversification and improvement of landmines. Aware of the material damage, but especially of the loss of human life and trauma caused to personnel by landmines, most of the world’s states have agreed to ban their use. However, recent or ongoing military conflicts illustrate a widespread use of landmines. Despite this, the international community must make every effort to ban the use of landmines.
Evaluation of the Efficiency of National Defense, Through the Data Envelopment Analysis Method
Authors: Huseraş Alin Teodor , Balteş Nicolae 
Published: July 2023

Abstract
This paper highlights certain possibilities for measuring the efficiency and performance of organizations, of economic processes or labor productivity, based on a set of input and output values, through the Data Envelopment Analysis (D.E.A.) method. The method is used in many fields of activity, especially in the medical system, education, finance, logistics, military, etc. The model is flexible and can be used for a wide range of activities and areas, allowing organizations to observe the aspects that can be improved and track the progress of the analyzed decision units to achieve the set objectives. The paper presents relevant studies by some prestigious authors who applied the D.E.A method in the defense sector, thus demonstrating that the method is a valuable tool that can be used in the evaluation of the efficiency of the defense sector. The last part of the paper is devoted to the pragmatic presentation of how to use the method.
Severe acute myxedematous psychosis; rare complication of hypothyroidism
Authors: Guerrouj Hasnae , Ennibi Ghizlane 
Published: July 2023

Background:
Severe acute myxedematous psychosis, or myxedema madness, is a rare and serious psychiatric complication of hypothyroidism. It is most often misdiagnosed, but it remains reversible after treatment with thyroid hormones.

Case Presentation:
We report a case of a patient without a known past medical history who underwent total thyroidectomy for papillary thyroid carcinoma. During her withdrawal from thyroid hormone therapy to perform a diagnostic radioiodine whole-body scintigraphy, she presented with anxiety, delirium, and hallucinations, culminating in a suicide attempt. Laboratory testing revealed a high sensible-thyroid stimulating hormone (TSH) value of 35 µIU/ml. The patient was hospitalized in a psychiatric unit, where she received antipsychotic medication and was started on thyroid hormones. After a week, there was a dramatic improvement. Psychiatric symptoms were completely gone a month later justifying the discontinuation of antipsychotics. Recombinant human TSH (rh-TSH) was necessary injected before radioiodine therapy to avoid thyroid hormone therapy suppression and to prevent a second episode of acute psychosis.

Conclusion:
rh-TSH interest is both in the pre Ira therapy stimulation and for the post-treatment monitoring of patients with thyroid cancer, and helps avoiding hormonal treatment suppression.
Sistem Rekomendasi Produk Menggunakan Metode User-Based Collaborative Filtering Pada Digital Marketing
Authors: Suhada Satia , Bahri Saeful , Nugraha Setyo Bagus , Hidayatulloh Taufik , Wintana Dede 
Published: July 2023

Sistem rekomendasi telah diterapkan dalam digital marketing yang digunakan dalam pemasaran produk dan jasa. Sistem rekomendasi digunakan untuk memberikan penawaran barang maupun jasa sesuai dengan kebiasaan dan minat pelanggan terhadap produk dan jasa yang diusulkan, namun pada prakteknya penawaran produk yang tepat untuk pelanggan mengarah pada ide mengembangkan sistem rekomendasi produk. Data pembelian yang didapat dari pelanggan dapat digunakan untuk menganalisis kebutuhan pelanggan dan preferensi produk. Pada sistem rekomendasi, Collaborative Filtering merupakan salah satu algoritma yang paling umum digunakan. Tujuan dari penelitian ini adalah untuk mengetahui seberapa akurat sistem rekomendasi berdasarkan pembelian barang yang serupa antar konsumen menggunakan User-based Collaborative Filtering. Berdasarkan hasil penelitian, User-based Collaborative Filtering menggunakan perhitungan Cosine Similarity dapat diterapkan dan menghasilkan 10 rekomendasi produk dengan nilai RMSE sebesar 0.9.
Network analysis applied to post-concussion symptoms in two mild traumatic brain injury samples
Authors: Faulkner Josh W. , Theadom Alice , Snell Deborah L. , Williams Matt N. 
Published: July 2023

ObjectiveA latent disease explanation cannot exclusively explain post-concussion symptoms after mild traumatic brain injury (mTBI). Network analysis offers an alternative form of explanation for relationships between symptoms. The study aimed to apply network analysis to post-concussion symptoms in two different mTBI cohorts; an acute treatment-seeking sample and a sample 10 years post-mTBI.MethodThe treatment-seeking sample (n = 258) were on average 6 weeks post-injury; the 10 year post mTBI sample (n = 193) was derived from a population-based incidence and outcomes study (BIONIC). Network analysis was completed on post-concussion symptoms measured using the Rivermead Post-Concussion Questionnaire.ResultsIn the treatment-seeking sample, frustration, blurred vision, and concentration difficulties were central to the network. These symptoms remained central in the 10 year post mTBI sample. A Network Comparison Test revealed evidence of a difference in network structure across the two samples (p = 0.045). However, the only symptoms that showed significant differences in strength centrality across samples were irritability and restlessness.ConclusionThe current findings suggest that frustration, blurred vision and concentration difficulties may have an influential role in the experience and maintenance of post-concussion symptoms. The impact of these symptoms may remain stable over time. Targeting and prioritising the management of these symptoms may be beneficial for mTBI rehabilitation.
Energy expenditure and weight-related behaviors in youth with Down syndrome: a protocol
Authors: Polfuss Michele , Bandini Linda G. , Ravelli Michele N. , Huang Zijian , Moosreiner Andrea , Schoeller Dale A. , Huang Chiang-Ching , Ding Dan , Berry Cristen , Marston Emma , Hussain Azeem , Shriver Timothy C. , Sawin Kathleen J. 
Published: July 2023

BackgroundThe consequences of obesity are ominous, yet healthcare professionals are not adequately preventing or treating obesity in youth with Down syndrome (DS). Total daily energy expenditure (TDEE) is the energy expended in 24 h through physical activity and life-sustaining physiologic processes. An individual's TDEE is essential for determining the daily caloric intake needed to maintain or change body weight. Successful prevention and treatment of obesity in youth with DS is severely compromised by the lack of data on TDEE and information on weight-related behaviors for this high-risk population. This manuscript describes the protocol for the federally funded study that is in process to determine daily energy expenditure in a large cohort of children with DS.MethodsThis observational cross-sectional study will include a national sample of 230 youth with DS, stratified by age (5–11 and 12–18 years of age) and sex. Doubly Labeled Water analysis will provide the criterion body fat%, fat-free mass, and TDEE. To increase accessibility and decrease the burden on participants, the entire study, including obtaining consent and data collection, is conducted virtually within the participant's home environment on weekdays and weekends. The study team supervises all data collection via a video conferencing platform, e.g., Zoom. This study will (1) examine and determine average TDEE based on age and sex, (2) develop a prediction equation based on measured TDEE to predict energy requirements with a best-fit model based on fat-free mass, sex, age, and height and/or weight, and (3) use 24-hour dietary recalls, a nutrition and physical activity screener, wearable devices, and sleep questionnaire to describe the patterns and quality of dietary intake, sleep, and physical activity status in youth with DS.DiscussionThe lack of accurate information on energy expenditure and weight-related behaviors in youth with DS significantly impedes the successful prevention and treatment of obesity for this vulnerable population. The findings of this study will provide a further understanding of weight-related behaviors as obesity risk factors, currently not well understood for this population. This study will advance the science of weight management in individuals with disabilities and shift clinical practice paradigms.