bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Potential and Concerns of Using AI in Scientific Research: ChatGPT Performance Evaluation
Authors: Khlaif Zuheir N , Mousa Allam , Hattab Muayad Kamal , Itmazi Jamil , Hassan Amjad A , Sanmugam Mageswaran , Ayyoub Abedalkarim 
Published: July 2023

Background
Artificial intelligence (AI) has many applications in various aspects of our daily life, including health, criminal, education, civil, business, and liability law. One aspect of AI that has gained significant attention is natural language processing (NLP), which refers to the ability of computers to understand and generate human language.

Objective
This study aims to examine the potential for, and concerns of, using AI in scientific research. For this purpose, high-impact research articles were generated by analyzing the quality of reports generated by ChatGPT and assessing the application’s impact on the research framework, data analysis, and the literature review. The study also explored concerns around ownership and the integrity of research when using AI-generated text.

Methods
A total of 4 articles were generated using ChatGPT, and thereafter evaluated by 23 reviewers. The researchers developed an evaluation form to assess the quality of the articles generated. Additionally, 50 abstracts were generated using ChatGPT and their quality was evaluated. The data were subjected to ANOVA and thematic analysis to analyze the qualitative data provided by the reviewers.

Results
When using detailed prompts and providing the context of the study, ChatGPT would generate high-quality research that could be published in high-impact journals. However, ChatGPT had a minor impact on developing the research framework and data analysis. The primary area needing improvement was the development of the literature review. Moreover, reviewers expressed concerns around ownership and the integrity of the research when using AI-generated text. Nonetheless, ChatGPT has a strong potential to increase human productivity in research and can be used in academic writing.

Conclusions
AI-generated text has the potential to improve the quality of high-impact research articles. The findings of this study suggest that decision makers and researchers should focus more on the methodology part of the research, which includes research design, developing research tools, and analyzing data in depth, to draw strong theoretical and practical implications, thereby establishing a revolution in scientific research in the era of AI. The practical implications of this study can be used in different fields such as medical education to deliver materials to develop the basic competencies for both medicine students and faculty members.
Temporal tracheobronchial lymphadenopathy resolution is affected by initial severity and poorly correlated to serologic antibody testing in dogs with pulmonary coccidioidomycosis
Authors: Urion Rebecca , Jaffey Jared A. , Hostnik Eric T. , Hanzlicek Andrew S. , Moore George E. 
Published: July 2023

Abstract

OBJECTIVE
To determine associations between antibody serologic tests and tracheobronchial lymphadenopathy (TBL) in dogs with pulmonary coccidioidomycosis and identify variables associated with time to resolution of TBL.

ANIMALS
32 client owned dogs with newly diagnosed pulmonary coccidioidomycosis from October 2020 to February 2021.

METHODS
Prospective cohort study. Thoracic radiographs and anti–Coccidioides spp antibody serology were performed at baseline and once every 3 months until remission or for a maximum of 12 months. Radiographic tracheobronchial lymph node height, length, and area were measured and recorded as ratios via comparison with the length of the T4 vertebral body (LT4) and length of the manubrium. Severity of TBL was also subjectively categorized as mild, moderate, or severe.

RESULTS
Tracheobronchial lymphadenopathy was identified in 81% (26/32; 95% CI, 64% to 93%) of dogs. There was no relevant association between TBL presence or severity and antibody serology results. Tracheobronchial lymphadenopathy resolved in 72% (n = 18) of dogs at the 3-month evaluation. The median time to resolution of TBL after initiation of fluconazole was 96 days (range, 72 to 386 days). Univariate analysis identified increasing TBL severity (hazard ratio, 0.40; 95% CI, 0.19 to 0.84; P = .02) and length:LT4 ratio (hazard ratio, 0.41; 95% CI, 0.20 to 0.82; P = .01) as variables associated with reduced probability of resolution of TBL.

CLINICAL RELEVANCE
Antibody serologic test results are not clinically useful to predict TBL presence or severity in dogs with pulmonary coccidioidomycosis, and larger tracheobronchial lymph nodes are more likely to take longer to resolve. Resolution of TBL occurs in most dogs within 3 to 6 months after fluconazole administration.
Experimental Study of Thermophysical Properties of TiO2 Nanofluid
Authors: Abdulwahab Majid I. , Thahab S.M. , Dhiaa Asmaa H. 
Published: July 2023

Titanium-dioxide (TiO2) nanoparticles suspended in water, and ethanol based fluids have been prepared using one step method and characterized by scanning electron microscopy (SEM), and UV–visible spectrophotometer. The TiO2 nanoparticles were added to base fluids with different volume concentrations from 0.1% to1.5% by dispersing the synthesized nanoparticles in deionized water and ethanol solutions. The effective thermal conductivity, viscosity and pH of prepared nanofluids at different temperatures from 15 to 30 oC were carried out and investigated. It was observed that the thermal conductivity, pH, and viscosity of nanofluids increases with the increase in TiO2 nanoparticle volume fraction. The thermal conductivity of TiO2 nanofluids significantly increases linearly with increasing particle vol. fraction at different temperature values and also it was found that the viscosity increases with increasing particle vol. fraction and decreases with the increase in temperature.
Validation of a Multivariate Prediction Model of the Clinical Progression of Alzheimer’s Disease in a Community-Dwelling Multiethnic Cohort
Authors: Stallard Eric , Kociolek Anton , Jin Zhezhen , Ryu Hyunnam , Lee Seonjoo , Cosentino Stephanie , Zhu Carolyn , Gu Yian , Fernandez Kayri , Hernandez Michelle , Kinosian Bruce , Stern Yaakov 
Published: July 2023

Background: The major aims of the three Predictors Studies have been to further our understanding of Alzheimer’s disease (AD) progression sufficiently to predict the length of time from disease onset to major disease outcomes in individual patients with AD. Objectives: To validate a longitudinal Grade of Membership (L-GoM) prediction algorithm developed using clinic-based, mainly white patients from the Predictors 2 Study in a statistically representative community-based sample of Hispanic (N = 211) and non-Hispanic (N = 62) older adults (with 60 males and 213 females) from the Predictors 3 Study and extend the algorithm to mild cognitive impairment (MCI). Methods: The L-GoM model was applied to data collected at the initial Predictors 3 visit for 150 subjects with AD and 123 with MCI. Participants were followed annually for up to seven years. Observed rates of survival and need for full-time care (FTC) were compared to those predicted by the algorithm. Results: Initial MCI/AD severity in Predictors 3 was substantially higher than among clinic-based AD patients enrolled at the specialized Alzheimer’s centers in Predictors 2. The observed survival and need for FTC followed the L-GoM model trajectories in individuals with MCI or AD, except for N = 32 subjects who were initially diagnosed with AD but reverted to a non-AD diagnosis on follow-up. Conclusion: These findings indicate that the L-GoM model is applicable to community-dwelling, multiethnic older adults with AD. They extend the use of the model to the prediction of outcomes for MCI. They also justify release of our L-GoM calculator at this time.
Reference Data for Attentional, Executive, Linguistic, and Visual Processing Tests Obtained from Cognitively Healthy Individuals with Normal Alzheimer’s Disease Cerebrospinal Fluid Biomarker Levels
Authors: López-Martos David , Brugulat-Serrat Anna , Cañas-Martínez Alba , Canals-Gispert Lidia , Marne Paula , Gramunt Nina , Suárez-Calvet Marc , Milà-Alomà Marta , Minguillon Carolina , Fauria Karine , Zetterberg Henrik , Blennow Kaj , Gispert Juan Domingo , Molinuevo José Luis , Grau-Rivera Oriol , Sánchez-Benavides Gonzalo ,   for the ALFA study
Published: July 2023

Background: Conventional neuropsychological norms likely include cognitively unimpaired (CU) individuals with preclinical Alzheimer’s disease (AD) pathology (amyloid-β, tau, and neurodegeneration) since they are based on cohorts without AD biomarkers data. Due to this limitation, population-based norms would lack sensitivity for detecting subtle cognitive decline due to AD, the transitional stage between healthy cognition and mild cognitive impairment. We have recently published norms for memory tests in individuals with normal cerebrospinal fluid (CSF) AD biomarker levels. Objective: The aim of the present study was to provide further AD biomarker-based cognitive references covering attentional, executive function, linguistic, and visual processing tests. Methods: We analyzed 248 CU individuals aged between 50–70 years old with normal CSF Aβ, p-tau, and neurodegeneration (t-tau) biomarker levels. The tests included were the Trail Making Test (TMT), Semantic Fluency Test, Digit and Symbol Span, Coding, Matrix Reasoning, Judgement of Line Orientation and Visual Puzzles. Normative data were developed based on regression models adjusted for age, education, and sex when needed. We present equations to calculate z-scores, the corresponding normative percentile tables, and online calculators. Results: Age, education, and sex were associated with performance in all tests, except education for the TMT-A, and sex for the TMT-B, Coding, and Semantic Fluency. Cut-offs derived from the current biomarker-based reference data were higher and more sensitive than standard norms. Conclusion: We developed reference data obtained from individuals with evidence of non-pathologic AD biomarker levels that may improve the objective characterization of subtle cognitive decline in preclinical AD.
Decoupling of Regional Cerebral Blood Flow and Brain Function Along the Alzheimer’s Disease Continuum
Authors: Li Jixuan , Zeng Qingze , Luo Xiao , Li Kaicheng , Liu Xiaocao , Hong Luwei , Zhang Xinyi , Zhong Siyan , Qiu Tiantian , Liu Zhirong , Chen Yanxing , Huang Peiyu , Zhang Minming ,   for the Alzheimer’s Disease Neuroimaging Initiative
Published: July 2023

Background: Alzheimer’s disease (AD) is accompanied with impaired neurovascular coupling. However, its early alteration remains elusive along the AD continuum. Objective: This study aimed to investigate the early disruption of neurovascular coupling in cognitively normal (CN) and mild cognitive impairment (MCI) elderly and its association with cognition and AD pathologies. Methods: We included 43 amyloid-β-negative CN participants and 38 amyloid-β-positive individuals (18 CN and 20 MCI) from the Alzheimer’s Disease Neuroimaging Initiative dataset. Regional homogeneity (ReHo) map was used to represent neuronal activity and cerebral blood flow (CBF) map was used to represent cerebral blood perfusion. Neurovascular coupling was assessed by CBF/ReHo ratio at the voxel level. Analyses of covariance to detect the between-group differences and to further investigate the relations between CBF/ReHo ratio and AD biomarkers or cognition. In addition, the correlation of cerebral small vessel disease (SVD) burden and neurovascular coupling was assessed as well. Results: Related to amyloid-β-negative CN group, amyloid-β-positive groups showed decreased CBF/ReHo ratio mainly in the left medial and inferior temporal gyrus. Furthermore, lower CBF/ReHo ratio was associated with a lower Mini-Mental State Examination score as well as higher AD pathological burden. No association between CBF/ReHo ratio and SVD burden was observed. Conclusion: AD pathology is a major correlate of the disturbed neurovascular coupling along the AD continuum, independent of SVD pathology. The CBF/ReHo ratio may be an index for detecting neurovascular coupling abnormalities, which could be used for early diagnosis in the future.
Effectiveness of eight or more antenatal contacts on health facility delivery and early postnatal care in low- and middle-income countries: a propensity score matching
Authors: Chilot Dagmawi , Aragaw Fantu Mamo , Belay Daniel Gashaneh , Asratie Melaku Hunie , Merid Mehari Woldemariam , Kibret Anteneh Ayelign , Teshager Nahom Worku , Alem Adugnaw Zeleke 
Published: July 2023

BackgroundDespite progress in reducing maternal and child mortality, many low- and middle-income countries (LMICs) still experience an unacceptably high level of the problem. The World Health Organization (WHO) recently recommended pregnant women should have at least eight antenatal care visits (ANC8+) with a trained healthcare provider as a key strategy to promote pregnant women's health. Antenatal care is an imperative factor for subsequent maternal healthcare utilization such as health facility delivery and early postnatal care (EPNC). This study aimed to examine the net impact of ANC8+ visits on health facility delivery and EPNC in LMICs using a propensity score matching analysis.MethodsWe used the recent Demographic and Health Survey (DHS) datasets from 19 LMICs. Women of reproductive age (15–49 years) who had given birth within 1 year preceding the survey were included. A propensity score matching analysis was employed to assess the net impact of eight or more antenatal care visits on health facility delivery and early postnatal care.ResultAfter matching the covariates, women who attended ANC8+ visits had a 14% (ATT = 0.14) higher chance of having their delivery at health facilities compared with women who attended less than eight ANC visits. This study further revealed that women who had ANC8+ visits were associated with a 10% (ATT = 0.10) higher probability of early PNC compared with their counterparts.Conclusion and recommendationThis study confirmed that ANC8+ visits significantly increased the likelihood of health facility-based delivery and early PNC utilization in LMICs. These findings call for public health programs to focus on pregnant women attending adequate ANC visits (according to revised WHO recommendation) as our study indicates that ANC8+ visits significantly improved the chances of subsequent care.
Combined versus sequential penetrating keratoplasty and cataract surgery for herpes simplex keratitis: a retrospective study
Authors: Wang Yani , Cheng Jun , Yang Nannan , Li Ting , Dong Yanling , Xie Lixin 
Published: July 2023

PurposeTo compare the surgical outcomes of combined penetrating keratoplasty (PK) and cataract surgery with those of sequential surgery (cataract surgery after PK) for herpes simplex keratitis (HSK).MethodsThe medical records of consecutive patients diagnosed with HSK who underwent combined or sequential PK and cataract surgery in active and stable stages between June 2015 and June 2022 were reviewed retrospectively. Complications, graft survival, endothelial cell density (ECD), and final BCVA were compared and analyzed between both surgical methods in each stage.ResultsA total of 171 eyes of 171 patients were enrolled, including active stage (69 combined, 46 sequential) and stable stage (34 combined, 22 sequential). The average follow up was 24.2 ± 15.8 months (range, 3 months – 48 months). The final BCVA had obvious improvement and the postoperative ECD was not different in combined and sequential groups of each stage. In sequential group of active stage, 66.7% of persistent epithelial defects and 50% of HSK recurrence occurred within 3 months after cataract surgery; nevertheless, compared to that in sequential group, capsular rupture (p = 0.021), persistent epithelial defects (p = 0.027), and HSK recurrence (p = 0.035) occurred more frequently in combined group, leading to a lower graft survival rate (p = 0.045); at the last visit, 46.4 and 67.4% of grafts remained clear in combined and sequential groups, respectively. By contrary, 82.4 and 50.0% of grafts remained clear in stable stages of combined and sequential groups at the last visit, respectively, and a higher graft survival rate was observed in combined group (p = 0.030).ConclusionAlthough the postoperative ECD is not different between two surgical groups in each stage, sequential surgery in active stage of HSK seems to have advantages in less complications and higher graft survival rate, whereas combined surgery in stable stage has a better outcome than that in sequential surgery.
Cancel culture can be collectively validating for groups experiencing harm
Authors: Traversa Marissa , Tian Ying , Wright Stephen C. 
Published: July 2023

IntroductionSocial psychological research on collective action and intergroup harm has yet to adequately consider the potential role of cancel culture or feelings of collective validation in motivating collective action. The current research will begin to fill this gap and may broaden our understanding of the psychological mechanisms that inspire and maintain collective action in response to intergroup harm. To our knowledge, this research is the first social psychological analysis of the impact of cancel culture on collective action and as means for producing feelings of collective validation.MethodsIn two experimental studies, participants read a story describing an event of discrimination against their group followed by a manipulation of the presence or absence of an episode of cancel culture. Study 1 samples woman university students (N = 520) and focuses on their responses to a sexist incident on campus. Study 2 (pre-registered) assesses the generality of the model in a racism context with a community sample of East Asian Canadians and Americans (N = 237).ResultsStudy 1 showed that an episode of cancel culture had an indirect positive effect on collective action intentions mediated by feelings of collective validation and collective empowerment. Study 2 showed the indirect effect of cancel culture on collective action intentions mediated by feelings of collective validation and collective anger and contempt.DiscussionThe current research offers a novel theoretical and empirical introduction to the concept of collective validation and the understudied context of cancel culture to the existing social psychological research and theory on collective action. Further, cancel culture has been criticized as problematic. However, this perspective centres those in positions of power. Through this research, we hope to shift the focus onto marginalized groups’ perspectives of episodes of cancel culture. This research shows that groups who experience harm find these episodes of cancel culture validating in ways that have yet to be fully explored by intergroup relations research. Further, these findings suggest that collective validation does mediate the relationship between cancel culture and collective action; thus, cancel culture becomes an important contributor to resistance by marginalized groups through collective validation.
Contact dermatitis caused by prevention measures during the COVID-19 pandemic: a narrative review
Authors: Tang Huimiao , Wang Hao , Hamblin Michael R. , Jiang Lu , Zhou Yanjun , Xu Yidan , Wen Xiang 
Published: July 2023

IntroductionDuring the outbreak of Coronavirus disease 2019 (COVID-19), health care workers wore personal protective equipment including masks, gloves and goggles for a long time. In order to reduce the transmission routes of the virus, public places were sprayed with disinfectant. Moreover, the body, hands and clothing were frequently disinfected and washed for hygiene purposes. Studies have shown that these practices could easily irritate the skin and damage the skin barrier. Long-term irritation or exposure to allergens may lead to the occurrence of contact dermatitis (CD).MethodsSubject headings were searched via the National Library of Medicine (PubMed) and web of science databases: COVID-19; contact dermatitis; adverse skin reaction; PPE; dermatitis; mask; glory; hand hygiene, disinfection; face shield; goggle; protect cloth. A total of 246 and 646 articles were retrieved from the two databases, respectively. 402 articles remained after removing duplicates. Reviews, non-English articles, articles that could not be accessed to read or did not conform to our topic were excluded. Finally, a total of 32 cross-sectional studies, 9 case reports and 2 randomized controlled trials were included.DiscussionThis article reviews reports of CD caused by various prevention and hygiene measures during the COVID-19 pandemic. The amount of skin damage caused by COVID-19 prevention measures could be decreased by improved education about skin management.
PENGARUH EDUKASI PROGRAM DUKUNGAN KELUARGA TERHADAP KUALITAS HIDUP PASIEN KANKER PAYUDARA DI MURNI TEGUH MEMORIAL HOSPITAL
Authors: Lase Desni Vidensia , Daniel Hasibuan Muhammad Taufik 
Published: July 2023

Breast cancer is a disease that can affect anyone, various kinds of treatment for the disease can cause physiological, physchological, and social peoblems. Breast cancer is an abnormal growth of cells in the breast which can sometimes be felt as a lump or mass which is often referred to as a tumor. Breast cancer greatly affects a person’s quality of life, this due to changes in physical and psychological terms. One of the factors that greatly affects the quality of life is a family support. Family support is the attitude, action and acceptance of the family towards family members. To identify the effect of family support program education on quality of life of breast cancer patients at murni teguh memorial hospital. This study used a pre-experimental design, using a one group pre-test post test design. Sampling using purposive sampling with a total sample of 44 respondents. The research instrument used was a questionnaire sheet. Analysis of the data used is the Paired Sample T Test. The result showed that there was an influence of family support program education on the quality of life of breast cancer patienst at murni teguh memorial hospital. Paired sample T Test statistic shows p value= 0.00. There is an effect of family support program education on the quality of life of breast cancer patients at murni teguh memorial hospital.

Abstrak
Kanker payudara merupakan suatu penyakit yang dapat menyerang siapa saja, berbagai macam pengobatan penyakit tersebut dapat menyebabkan masalah fisiologis, psikologis, dan sosial. Kanker payudara merupakan pertumbuhan sel yang tidak normal pada payudara yang terkadang dapat dirasakan sebagai benjolan atau massa yang sering disebut dengan tumor. Kanker payudara sangat mempengaruhi kualitas hidup seseorang, ini disebabkan karena terjadinya perubahan dari segi fisik dan segi psikologisnya. Salah satu faktor yang sangat mempengaruhi kualitas hidup adalah dukungan keluarga. Dukungan keluarga merupakan sikap, tindakan dan penerimaan keluarga terhadap anggota keluarganya. Untuk mengidentifikasi pengaruh edukasi program dukunan keluarga terhadap kualitas hidup pasien kanker payudara di murni teguh memorial hospital. Penelitian ini menggunakan rancangan pre eksperimen, dengan menggunakan design one group pre test - post test. Pengambilan sampel menggunakan purposive sampling dengan jumlah sampel sebanyak 44 responden. Instrumen penelitian yang digunakan berupa lembar penilaian kuesioner. Analisis data yang digunakan adalah paired sample T Test. Hasil penelitian menunjukkan ada pengaruh edukasi program dukungan keluarga terhadap kualitas hidup pasien kanker payudara di murni teguh memorial hospital. Statistik paired sample T Test menunjukkan nilai p= 0.00. Ada pengaruh edukasi program dukungan keluarga terhadap kualitas hidup pasien kanker payudara di murni teguh memorial hospital.