bluuebunny/crossref_metadata_2025_split huggingface dataset:
The significance of N-carbamoylglutamate in ruminant production
Authors: McCoard Susan A. , Pacheco David 
Published: April 2023

AbstractImproving the efficiency and production of grazing ruminants to support food and fiber production, while reducing the environmental footprint and meeting the welfare needs of the animals, is important for sustainable livestock production systems. Development of new technologies that can improve the efficiency of nitrogen (N) utilization in ruminants, and that are effective and safe, has important implications for ruminant livestock production. N-carbomoylglutamate (NCG) is a functional micronutrient that stimulates endogenous synthesis of arginine, which can improve survival, growth, lactation, reproductive performance, and feed efficiency in mammals. There is a growing body of evidence to support the potential of dietary NCG supplementation to improve the productive capacity and N utilization efficiency of ruminants. This review summarizes the current literature on the effects of dietary supplementation with NCG in ruminants and impacts on production and potential to reduce the environmental footprint of farmed ruminant livestock. The current literature highlights the potential for commercial application in ruminant livestock to improve productivity and N utilization efficiency.
Experiences of burnout, anxiety, and empathy among health profession students in Qatar University during the COVID-19 pandemic: a cross-sectional study
Authors: Sulaiman Ruba , Ismail Sara , Shraim Mujahed , El Hajj Maguy Saffouh , Kane Tanya , El-Awaisi Alla 
Published: April 2023

Abstract
Background
The prevalence of burnout and anxiety is constantly increasing among health profession students worldwide. This study evaluates the prevalence of burnout and its relationship to anxiety and empathy during the COVID-19 pandemic among health profession students in the main governmental institution in Doha, Qatar using validated instruments.

Methods
A cross-sectional survey of health profession students using validated instruments was employed. The Maslach Burnout Inventory-General Students Survey (MBI-GS(S)) to measure burnout; The Generalized Anxiety Disorder (GAD-7) to measure anxiety; and Interpersonal Reactivity Index (IRI) to measure empathy were utilized. Descriptive statistics and multivariable linear regression were used.

Results
Of the 1268 eligible students, 272 (21.5%) completed the online survey. Burnout was found to be prevalent amongst the students. The mean scores for the MBI-GS(S) subscales of emotional exhaustion, cynicism, and professional efficacy were 4.07, 2.63, and 3.97, respectively. Anxiety was found to be a strong predictor for burnout and burnout was positively associated with empathy.

Conclusions
Findings from this study demonstrated relationships between health profession students’ burnout, anxiety, and empathy. These findings might have an impact on the development of curriculum interventions to enhance student well-being. More burnout awareness and management programs that cater to the specific needs of health profession students are needed. Furthermore, findings of this study may have implications for future educational interventions during times of crisis or how this can be used to improve student experiences in normal times.
Acquisition strategies for in-situ hyperspectral imaging of stained-glass windows: case studies from the Swiss National Museum
Authors: Babini Agnese , Lombardo Tiziana , Schmidt-Ott Katharina , George Sony , Hardeberg Jon Yngve 
Published: April 2023

Abstract
Over the last decade, hyperspectral imaging has become a popular technique for the non-invasive identification and mapping of painting materials in many typologies of artworks, thanks to the possibility of obtaining spectral information over the spatial region. A few attempts have also been made on stained-glass windows to identify the chromophore elements responsible for glass color. Hyperspectral imaging of stained glass can be complex; in most cases, stained-glass windows are an integral part of buildings, and sunlight represents the natural light source for illuminating these artifacts. While it may be considered an advantage, sunlight is not homogeneous throughout the day, and different weather conditions can affect the quality of the hyperspectral images. In addition, the presence of buildings and vegetation in the background could also modify the colors of the stained-glass windows and consequently alter the characteristic peaks of the chromophores in the spectra. This work aims to solve some of these issues and proposes different strategies to improve the results obtainable in situ. The methodology was tested on stained-glass panels displayed in the windows of the Swiss National Museum. Stained-glass panels located in windows of an internal wall were also analyzed, developing a lighting setup to account for the lack of natural light. Hyperspectral images of the selected stained glass were acquired multiple times, choosing different transmittance references for the preprocessing and exposure time to evaluate differences in the collected spectral images. The use of a diffuser sheet to mitigate the effect of external factors was also tested on some panels exposed to sunlight. Results from representative case studies will be presented to discuss the feasibility and limitations of in-situ hyperspectral imaging applications on stained glass and provide some general recommendations to consider during the acquisitions.
Simulated distributions of pumice rafts in Japan following eruptions at volcanic islands and submarine volcanoes
Authors: Nishikawa Haruka , Kuwatani Tatsu , Tada Noriko , Kayama Watanabe Hiromi 
Published: April 2023

AbstractVoluminous pumice rafts produced by the 2021 phreatomagmatic eruption of Fukutoku-Oka-no-Ba, a submarine volcano located in the Izu-Bonin Islands, reached many Japanese ports and islands, damaging fisheries and hindering marine traffic and trade. This event emphasized the necessity for governments and stakeholders to develop plans in advance and prepare disaster mitigation measures before an eruption. To investigate when and to what extent pumice might intersect trade routes and arrive at islands after future eruptions, we conducted particle tracking simulations of eruptions at major volcanic islands and submarine volcanoes near Japan using the velocity field from the ocean reanalysis dataset. Seven major volcanoes that have produced pumice rafts in the past century were selected: the submarine volcano NNE of Iriomote Island, Izu-Tobu Volcanoes, Miyakejima, Bayonnaise Rocks, Nishinoshima, Kaitoku Seamount, and Fukutoku-Oka-no-Ba. We partly reproduced the distribution of pumice arrivals recorded after the 1986 Fukutoku-Oka-no-Ba eruption, demonstrating the potential effectiveness of the simulations. We report likely pumice raft arrivals and drifting durations for the investigated eruptive scenarios, which may aid future risk assessments for pumice arrivals.
The effect of Universal Teacher–Child Interaction Training on Hispanic teachers’ sense of self-efficacy in early childhood education and care settings
Authors: Rivas Alexandra , Mooss Angela , Pontier Christine Hughes , Romillo Jackie , Muñoz Emma 
Published: April 2023

AbstractDisparities exist in the availability of high-quality early childhood education and care settings (ECEC) across communities within the United States. Teachers have an imperative role in fostering children’s socioemotional development; however, when the classroom climate deteriorates due to disruptive behavior, meeting these emotional and learning needs becomes more difficult. Dealing with challenging behaviors can lead to emotional exhaustion which is directly linked to a decrease in teacher sense of efficacy. Teacher–Child Interaction Training-Universal (TCIT-U) targets teachers’ skills to provide quality interactions and decrease child behavior problems. Despite evidence that teacher sense of self-efficacy can inhibit negative teaching practices, a lack of research has explored this construct as related to TCIT-U. The current study is a randomized, wait-list control study measuring the change of teachers’ sense of self-efficacy after participating in TCIT-U, and the first known of its kind. The study included mostly Hispanic (96.4%) teachers (N = 84) of ECEC programs across 13 unique sites serving 900 children ages 2–5 years from low-income, urban areas. Results from inferential statistics and hierarchical linear regression tests demonstrated TCIT-U as an effective intervention to improve teachers’ sense of efficacy in classroom management, instructional strategies, and student engagement. In addition, this study contributes to the effectiveness of TCIT-U as an in-service training which targets teacher communication skills for teachers with diverse backgrounds in ECEC settings with mostly dual language learners.
Minimally invasive cardiac surgery via bilateral thoracotomy in treatment of left ventricle aneurysm: a case report
Authors: Kanazawa Yuta , Saito Shunsuke , Shibasaki Ikuko , Matsuoka Taiki , Hirota Shotaro , Yokoyama Shouhei , Kanno Yasuyuki , Tezuka Masahiro , Tsuchiya Go , Konishi Taisuke , Ogata Koji , Fukuda Hirotsugu 
Published: April 2023

Abstract
Background
Left ventricle aneurysm (LVA) as a sequela to myocardial infarction or iatrogenic injury is required surgical treatment with full median sternotomy. Herein, we report a case of successful surgical treatment of left ventricle aneurysm performed by minimally invasive cardiac surgery (MICS).

Case presentation
We describe a case of a LVA treated by minimally invasive cardiac surgery in an 82-year-old woman who reported to the hospital with the complaint of chest pains at rest. Computed tomography (CT) coronary angiography revealed a left ventricle apical aneurysm. The aneurysm was suspected to be a pseudoaneurysm caused by a previous myocardial infarction. Surgery was performed under general anesthesia, with the patient in a supine position. A small incision was made in the 3rd intercostal space through which an aortic root vent cannula and aortic clamp were inserted, followed by exposing the aneurysm via incision of the left 6th intercostal space. The aneurysm was resected and pathologically examined, revealing it to be a “true” aneurysm. The left ventricle wall was closed using polypropene mattress sutures. Postoperative CT scan revealed successful resection of the aneurysm. Usually, a surgical treatment with full median sternotomy and left ventriculostomy is indicated for LVA. We decided to treat the LVA with bilateral thoracotomy MICS. We preferred to perform this procedure under cardiac arrest to ensure safe and secure closure of the aneurysm. The right small thoracotomy was necessary for aortic cross-clamping and aortic root venting.

Conclusions
The procedure was safe and simple and yielded excellent postoperative outcomes. Therefore, we speculate that this method can be applied to the management of larger aneurysms.
In-silico characterization of the relationship between the Porcine reproductive and respiratory syndrome virus prevalence at the piglet and litter levels in a farrowing room
Authors: Osemeke Onyekachukwu H. , de Freitas Costa Eduardo , Weide Vinicius , Jayaraman Swaminathan , Silva Gustavo S. , Linhares Daniel C. L. 
Published: April 2023

AbstractBackgroundFamily oral fluids (FOF) sampling has been described as a sampling technique where a rope is exposed to sows and respective suckling litters and thereafter wrung to obtain fluids. PCR-based testing of FOF reveals presence of PRRS virus RNA only at the litter level, as opposed to conventional individual-animal-based sampling methods that demonstrate PRRSV RNA at the piglet level. The relationship between the PRRSV prevalence at the individual piglet level and at the litter level in a farrowing room has not been previously characterized. Using Monte Carlo simulations and data from a previous study, the relationship between the proportion of PRRSV-positive (viremic) pigs in the farrowing room, the proportion of litters in the farrowing room with at least one viremic pig, and the likely proportion of litters to be positive by a FOF RT-rtPCR test in a farrowing room was characterized, taking into account the spatial distribution (homogeneity) of viremic pigs within farrowing rooms.ResultsThere was a linear relationship between piglet-level- and litter-level prevalence, where the latter was always larger than the former. When the piglet-level prevalence was 1%, 5%, 10%, 20%, and 50%, the true-litter level prevalence was 5.36%, 8.93%, 14.29%, 23.21%, and 53.57%, respectively. The corresponding apparent-litter prevalence by FOF was 2.06%, 6.48%, 11.25%, 21.60%, and 51.56%, respectively.ConclusionThis study provides matching prevalence estimates to help guide sample size calculations. It also provides a framework to estimate the likely proportion of viremic pigs, given the PRRSV RT-rtPCR positivity rate of FOF samples submitted from a farrowing room.
Anesthetic management of external iliac artery transection in a morbidly obese patient with Klippel-Trenaunay-Weber syndrome: a case report
Authors: Hirai Naoki , Kinoshita Hirotaka , Kitayama Masato , Kushikata Tetsuya , Hirota Kazuyoshi 
Published: April 2023

Abstract
Background
We report the anesthetic management of an external iliac artery transection in a morbidly obese patient with Klippel-Trenaunay-Weber syndrome (KTWS).

Case presentation
A 47-year-old man with KTWS was scheduled for a right external iliac artery transection. Preoperative CT showed a right external iliac artery aneurysm, a right superficial femoral artery aneurysm, and developed collateral vessels. General anesthesia was maintained with desflurane, remifentanil, and rocuronium bromide. After the transection of the right external iliac artery, the regional saturation of oxygen (rSO2) value of the right femoral did not decrease. There was no significant hemodynamic change before or after the transection. A non-ultrasound-guided rectus abdominis sheath block was performed due to the many collateral vessels. After extubation, the patient did not complain of postoperative pain.

Conclusions
In the transection of lower-extremity blood arteries under laparotomy in patients with KTWS, rSO2 monitoring, hemodynamic monitoring, and combined regional anesthesia could be useful.
Infant and young child feeding practices and the factors that influence them: a qualitative study
Authors: Weber Mary Beth , Palmer Wendy , Griffin Monica , Welsh Jean A. 
Published: April 2023

Abstract
Background
Early child feeding is important for healthy growth and forming positive eating behaviors.

Methods
This qualitative study sought to describe early childhood feeding behaviors, challenges, and opportunities through four focus group discussions with a diverse group of mothers of at least one child under two years or pregnant with their first child.

Results
Although providing healthy foods was a priority, feeding behaviors reflected the mothers’ partial understanding of infant and child nutrition. Mothers sought guidance on early child feeding from several sources, including in-person and virtual relationships but made decisions based largely on their own instincts. Participants consulted clinicians the least often, and mothers often felt frustrated by strict guidelines and negative messaging. Mothers were most receptive to suggestions when they felt supported and valued in the decision-making process.

Conclusions
In order to help mothers provide the best nutrition for their young children, clinicians should use positive tones, provide flexibility when possible, and work to create open lines of communication with parents.
γ-tocotrienol regulates gastric cancer by targeting notch signaling pathway
Authors: Xie Ling , Yan Juan 
Published: April 2023

Abstract
Background
Gastric cancer is a common cause of death from cancer and an important global health care issue. Consequently, there is an urgent need to find new drugs and therapeutic targets for the treatment of gastric cancer. Recent studies have shown that tocotrienols (T3) have significant anticancer ability in cancer cell lines. Our previous study found that γ-tocotrienol (γ-T3) induced apoptosis in gastric cancer cells. We further explored the possible mechanisms of γ-T3 therapy for gastric cancer.

Methods
In this study, we treated gastric cancer cells with γ-T3, collect and deposit the cells. γ-T3-treated gastric cancer cells group and untreated group were subjected to RNA-seq assay, and analysis of sequencing results.

Results
Consistent with our previous findings, the results suggest that γ-T3 can inhibit mitochondrial complexes and oxidative phosphorylation. Analysis reveals that γ-T3 has altered mRNA and ncRNA in gastric cancer cells. Significantly altered signaling pathways after γ-T3 treatment were enriched for human papillomavirus infection (HPV) pathway and notch signaling pathway. The same significantly down-regulated genes notch1 and notch2 were present in both pathways in γ-T3-treated gastric cancer cells compared to controls.

Conclusions
It is indicated that γ-T3 may cure gastric cancer by inhibiting the notch signaling pathway. To provide a new and powerful basis for the clinical treatment of gastric cancer.
Utilizing 3D printing to assist pre-procedure planning of transjugular intrahepatic portosystemic shunt (TIPS) procedures: a pilot study
Authors: Richards Lucas , Dalla Shiv , Fitzgerald Sharon , Walter Carissa , Ash Ryan , Miller Kirk , Alli Adam , Rohr Aaron 
Published: April 2023

Abstract
Background
3D (three-dimensional) printing has been adopted by the medical community in several ways, procedure planning being one example. This application of technology has been adopted by several subspecialties including interventional radiology, however the planning of transjugular intrahepatic portosystemic shunt (TIPS) placement has not yet been described. The impact of a 3D printed model on procedural measures such as procedure time, radiation exposure, intravascular contrast dosage, fluoroscopy time, and provider confidence has also not been reported.

Methods
This pilot study utilized a quasi-experimental design including patients who underwent TIPS. For the control group, retrospective data was collected on patients who received a TIPS prior to Oct 1, 2020. For the experimental group, patient-specific 3D printed models were integrated in the care of patients that received TIPS between Oct 1, 2020 and April 15, 2021. Data was collected on patient demographics and procedural measures. The interventionalists were surveyed on their confidence level and model usage following each procedure in the experimental group.

Results
3D printed models were created for six TIPS. Procedure time (p = 0.93), fluoroscopy time (p = 0.26), and intravascular contrast dosage (p = 0.75) did not have significant difference between groups. Mean radiation exposure was 808.8 mGy in the group with a model compared to 1731.7 mGy without, however this was also not statistically significant (p = 0.09). Out of 11 survey responses from interventionists, 10 reported “increased” or “significantly increased” confidence after reviewing the 3D printed model and all responded that the models were a valuable tool for trainees.

Conclusions
3D printed models of patient anatomy can consistently be made using consumer-level, desktop 3D printing technology. This study was not adequately powered to measure the impact that including 3D printed models in the planning of TIPS procedures may have on procedural measures. The majority of interventionists reported that patient-specific models were valuable tools for teaching trainees and that confidence levels increased as a result of model inclusion in procedure planning.
Developing a gamified artificial intelligence educational robot to promote learning effectiveness and behavior in laboratory safety courses for undergraduate students
Authors: Yang Qi-Fan , Lian Li-Wen , Zhao Jia-Hua 
Published: April 2023

AbstractAccording to previous studies, traditional laboratory safety courses are delivered in a classroom setting where the instructor teaches and the students listen and read the course materials passively. The course content is also uninspiring and dull. Additionally, the teaching period is spread out, which adds to the instructor's workload. As a result, students become less motivated to learn. In contrast, artificially intelligent educational robots (AIERs), help students learn while lessening the workload on instructors by enhancing teaching strategies, using robots to substitute for teachers, giving students access to a variety of instructional content, and improving interaction with students through the use of intelligent voice interactions and Q&A systems to promote student engagement in learning. If the robot is used for a long time for learning, it may lead to a decrease in students' interest in learning. Therefore, this study introduces the GAFCC model (the theory-driven gamification goal, access, feedback, challenge, collaboration design model) as an instructional design model to guide the development of a gamified AIER system, aiming to improve students' motivation and learning effectiveness for laboratory safety courses. To test the effectiveness of the system, this study conducted an experimental study at a university in China in the summer of 2022. 53 participants participated in the research, with a random sample taken from each group. Each participant was able to choose the time of their free time to engage in the experiment. There were 18, 19, and 16 participants in experimental group 1, experimental group 2, and the traditional group, respectively. Students in experimental group 1 learned using the gamified AIER system, students in experimental group 2 learned on a general anthropomorphic robot system and the control group received traditional classroom learning. The experimental results showed that compared to the other two groups, the gamified AIER system guided by the GAFCC model significantly improved students' learning achievement and enhanced their learning motivation, flow experience, and problem-solving tendency. In addition, students who adopted this approach exhibited more positive behaviors and reduced cognitive load in the learning process.