bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of educating health promotion strategies model on self-care self-efficacy in elderly with kidney transplantation
Authors: Hoseinian Masoumeh , Mohebi Mahsa , Sadat Zohreh , Ajorpaz Neda Mirbagher 
Published: April 2023

BACKGROUND:
After kidney transplantation, older adults encounter numerous problems which can negatively affect their self-care self-efficacy. According to studies, behavior modeling training has an effect on patient's self-care. Therefore, the present study was conducted to determine the effect of implementing health promotion strategies on self-care self-efficacy in older adults undergoing kidney transplantation.

MATERIALS AND METHODS:
This quasi-experimental study was conducted on 60 older adults undergoing kidney transplantation in Tehran's Shahid Doctor Labbafinejad Hospital in 2020. Patients were randomly divided into intervention and control groups by using block randomization method. For the patients of the intervention group, the educations were provided based on the model of individual health promotion strategies in eight sessions (i.e., 8 weeks, one session per week) for 40–60 minutes. The subjects of the control group received only their routine care. The two groups completed on-line the self-care self-efficacy questionnaire, before, immediately after and one month after the intervention. The results were analyzed by Chi-square, t-test and repeated measures analysis of variance in SPSS v19.

RESULTS:
According to the results, no significant difference was observed between the two groups in terms of demographic characteristics and the mean score of self-care self-efficacy before the intervention (P > 0.05). The mean score of self-care self-efficacy (P = 0.001) and some of its dimensions including stress reduction (P = 0.01) and adaptability (P = 0.01) was significantly different in the two groups in the three time intervals. Moreover, the two dimensions of decision making (P = 0.07) and enjoying the life (P = 0.20) were not significant.

CONCLUSION:
According to the results, education based on health promotion strategies can effectively improve self-care self-efficacy and some its dimensions. Therefore, teaching health promotion strategies as a low-cost and simple method can positively affect self-care self-efficacy in older adults undergoing kidney transplantation.
Malaria treatment failure after Artemisinin-based combination therapy: A case series of children managed at a private tertiary hospital in southwest Nigeria
Authors: Fatunla O.A.T. , Irek E.O.. , Oyebanji A.H. , Adisa S.O. , Jesulana T.E. , Jesulana T.E. , Ajibola T.O. 
Published: April 2023

Malaria treatment failure is the inability to clear parasitaemia after antimalarial drug administration. There are reports of treatment failure with artemisinin-based combination therapy (ACT) in Nigeria but few reported among children. We report three paediatric cases of treatment failure with ACT admitted at a private tertiary hospital in Nigeria in early 2022. All three were ‘under-fives’ admitted for open-heart surgery, major flame burns, and cerebral malaria respectively. They had symptomatic Plasmodium falciparum infection but one had mixed P. falciparum and Plasmodium vivax infections. Cases 1 and 2 were initially given oral artemether-lumefantrine while case 3 received intravenous artesunate. Despite appropriate antimalarial drug compliance, all the 3 still had fever with heavy parasitaemia. They subsequently received intravenous quinine, with improvement within the first 24 hours of therapy, and no longer had fever at the fourth week of follow-up. Although ACT resistance was not established, poor drug quality may have contributed to treatment failure. There is a need for pharmacovigilance of anti-malarial in Nigeria.

French title: Échec du traitement du paludisme après une polythérapie à base d'artémisinine: une série de cas d'enfants pris en charge dans un hôpital tertiaire privé du sud-ouest du Nigeria
L'échec du traitement du paludisme est l'incapacité à éliminer la parasitémie après l'administration d'un médicament antipaludique. Il y a des rapports d'échec de traitement avec la thérapie combinée à base d'artémisinine (ACT) au Nigeria, mais peu ont été signalés chez les enfants. Nous rapportons trois cas pédiatriques d'échec de traitement avec ACT admis dans un hôpital tertiaire privé au Nigeria au début de 2022. Tous trois étaient des « moins de cinq ans » admis pour une chirurgie à cœur ouvert, des brûlures graves par la flamme et un paludisme cérébral, respectivement. Ils avaient une infection symptomatique à Plasmodium falciparum mais un avait des infections mixtes à P. falciparum et Plasmodium vivax. Les cas 1 et 2 ont initialement reçu de l'artéméther-luméfantrine par voie orale tandis que le cas 3 a reçu de l'artésunate par voie intraveineuse. Malgré une bonne observance des médicaments antipaludiques, tous les 3 avaient encore de la fièvre avec une forte parasitémie. Ils ont ensuite reçu de la quinine par voie intraveineuse, avec une amélioration dans les 24 premières heures de traitement, et n'avaient plus de fièvre à la quatrième semaine de suivi. Bien que la résistance à l'ACT n'ait pas été établie, la mauvaise qualité des médicaments peut avoir contribué à l'échec du traitement. Il y a un besoin de pharmacovigilance des antipaludéens au Nigeria.
Rendimiento neuromuscular en niños tenistas de diferentes niveles de práctica: recreativos vs competitivos (Neuromuscular performance in pre-pubertal tennis players of different levels of practice: recreational vs. Competitive)
Authors: Cruz Wendy R. , Parra  Juan E. , Samudio   Laura V. , Trujillo  David R. , Celis-Moreno Mauricio 
Published: April 2023

El tenis es un deporte que depende del rendimiento neuromuscular para tener un mejor desempeño, independientemente del nivel de práctica. El objetivo de este estudio fue describir la asociación entre variables antropométricas y rendimiento neuromuscular niños tenistas (n=36) pre-púberes, en un rango de edad de (10.15-12.77) años, además de compararlos según el nivel de práctica. Los participantes fueron divididos en dos grupos, el primero fue denominado “competitivos”, con ranking nacional (n=18) edad (11.66 ± .72) y el segundo denominado “recreativos” sin ranking nacional (n=18) edad (11.52 ± .82). Se realizó una antropometría básica incluyendo estatura, peso y masa grasa, además se ejecutaron pruebas de CMJ, lanzamientos de balón medicinal de 2kg con tres técnicas diferentes (derecha, revés y por encima de la cabeza), y velocidades de 10m y 20m. En la comparación de grupos se encontraron diferencias (p≤0.01) en la masa grasa, CMJ y la prueba de 20m, y (p≤0.05) en los lanzamientos de balón medicinal y 10m. La estatura y el CMJ se asociaron a las otras variables evaluadas y los jugadores de nivel competitivo tuvieron mejores atributos antropométricos y neuromusculares que sus contemporáneos de nivel recreativo, tal vez por adaptaciones en edades pre-púberas al tiempo dedicado a la práctica, y a la exigencia competitiva.
Palabras clave: Tenis, deporte infanto-juvenil, potencia, velocidad.
Abstract. Tennis is a sport that depends on neuromuscular performance during the game, regardless of the level of practice. This study aimed to describe the association between anthropometric and neuromuscular performance in pre-pubertal children tennis players (n=36) aged (10.15-12.77) years and compare them according to the level of practice. The participants were divided into two groups; the first was called "competitive," with a national ranking (n=18) aged (11.66 ± .72), and the second called "recreational" non-ranked in the national system (n=18) aged (11.52 ± .82). Basic anthropometry, including height, weight, and fat mass, was performed, as well as CMJ tests, 2kg medicine ball throws with three different techniques (forehand, backhand, and overhead), and 10m and 20m distance speeds. The comparison by groups t- student test found differences of (p≤0.01) in fat mass, CMJ, and the 20m test, and (p≤0.05) in the medicine ball throw and 10m. The height and CMJ variables were strongly associated with the other variables evaluated and competitive-level players had fitter anthropometric and neuromuscular attributes than their recreational-level contemporaries, perhaps due to adaptations in pre-pubertal ages to the time dedicated to the practice and the competitive demand.
Keywords: Tennis, youth sports, power, speed.
Inovasi produk TOGA Immunomodulator dan budidayanya
Authors: Kurniawati Darini , Hidayah Nurul , Malahayati Siti 
Published: April 2023

The Covid-19 pandemic has an impact on partners and they want to innovate businesses that are needed by the community, namely herbal products that can increase endurance but are more durable and can be stored. Methods with education and practice of making traditional herbal instant powder preparations by conventional means of crystallization by heating and adding granulated sugar. Jamu powder is packaged and labeled as partners. Business licensing assistance has been carried out and has sold it directly or digital marketing with Instagram and WhatsApp promotional posters. Raw material efforts are assisted by cultivating the immunomodulator TOGA in the partner's yard. Evaluation of education by conducting a pre-test and post-test with the results obtained an increase in the category of good knowledge level by 58%. Evaluation of production that sells a lot is red ginger instant powder, while TOGA cultivation thrives waiting for harvest age. Abstrak: Pandemi Covid-19 berdampak terhadap mitra dan menginginkan berinovasi usaha yang diperlukan masyarakat yaitu produk herbal yang bisa meningkatkan daya tahan tubuh tapi lebih awet dan bisa disimpan. Metode dengan edukasi dan praktek pembuatan sediaan serbuk instan jamu tradisional dengan cara konvensional kristalisasi melalui pemanasan dan penambahan gula pasir. Serbuk jamu dikemas dan diberi label mitra. Pendampingan perijinan usaha sudah dilakukan dan sudah menjualnya secara langsung maupun marketing digital dengan poster propmosi Instagram dan whattshap. Upaya bahan baku dibantu dengan budidaya TOGA imunomodulator di lahan pekrangan mitra. Evaluasi edukasi dengan melakukan pre-test dan post-test dengan hasil diperoleh kenaikan kategori tingkat pengetahuan baik sebesar 58%. Evaluasi produksi yang banyak terjual yaitu serbuk instan jahe merah, sedangkan budidaya TOGA tumbuh subur menunggu usia panen.
Understanding the relationship between domestic and intimate partner violence, adverse childhood experiences, and chronic opioid use disorder: The patient perspective
Authors: Thiesset, PhD, MPH Heather F. , Barber, MS Melinda , Moore Braydonn , Van Komen Amelia , Crandall, PhD AliceAnn 
Published: April 2023

Introduction: Opioid dependence and misuse are a plague of epidemic proportions in our communities and globally. Prior trauma in childhood may contribute to opioid dependence, while one consequence of opioid misuse is increased risk for involvement as both perpetrators and victims in domestic and intimate partner violence (DV and IPV). The aims of this study were to understand the proportion of patients who identified as having an opioid use disorder (OUD), if OUD was associated with higher rates of DV and IPV as both perpetrators and victims, and whether adverse childhood experiences (ACEs) as well as demographic factors related to instability in their social life were higher among those with OUD compared to those without.
Methods: The sample consisted of 124 patients who were identified as having an OUD in their medical records based on ICD-10 codes. Each participant completed an anonymous survey about basic demographics, their alcohol, drug, and opioid intake, and their history of domestic and IPV. Descriptive statistics, univariate, and multivariate regression analyses were conducted in STATA 17.1 software.
Results: A sample of patients with an OUD diagnosis in their medical record found that 64 percent of patients acknowledged having a history of opioid addiction. Patients acknowledging OUD were more likely to not be married (divorced or single) (p < 0.01), younger than 50 years of age (p < 0.01), non-White (p < 0.01), and had higher average ACEs scores (p < 0.0X). Patients who reported OUD were also more likely to be both victims and perpetrators of DV/IPV compared to patients who denied OUD.
Discussion: OUD needs to be treated holistically to ensure that the adverse consequences of DV and IPV do not become a silent disease perpetuated on this population, their families, and society.
As aporias do sagrado e do sublime no cinema de Andrei Tarkovski
Authors: Silva David Thyago Luiz 
Published: April 2023

A contribuição deste artigo reside em uma tentativa de equacionar o problema que envolve os estudos estéticos e sua relação com o sagrado, a partir do aporte teórico de Rudolf Otto sobre o numinoso e dos cânones filosóficos da categoria do sublime, feito Schiller e Longino, desaguando, assim, no potente cinema do diretor russo Andrei Tarkovski, especificamente, em seu filme O espelho (1975); e também por seu pensamento teórico, cuja ideia percebia nas imagens cinematográficas janelas, por assim dizer, em que o homem pode ter acesso a fruições espirituais.Apesar da dificuldade intrínseca do problema, queremos demonstrar, através de exemplos do filme, a relação fronteiriça que a obra do cineasta russo manteve entre uma experiência genuinamente estética e uma experiência que flerte com o sagrado.
Durvalumab (Imfinzi)
Authors: CADTH  
Published: April 2023

CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class.
The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec.
This review assesses durvalumab (50 mg/mL) concentrate for solution for IV infusion, 1,500 mg in combination with chemotherapy every 3 weeks (q.3.w.), followed by 1,500 mg every 4 weeks (q.4.w.) as monotherapy until disease progression or unacceptable toxicity.
Indication: In combination with gemcitabine-based chemotherapy, for the treatment of patients with locally advanced or metastatic biliary tract cancer (BTC).
Estrategia educativa para dar tratamiento a la educación vial en el proceso de formación inicial del estudiante de la Licenciatura en Educación Preescolar
Authors: Ramírez González Yarileisys , Frómeta Griñón Imayasil , Martínez Pacheco Iliana 
Published: April 2023

En los momentos actuales las universidades deben contribuir a la formación de una adecuada cultura vial en los estudiantes, mediante el aprovechamiento de las posibilidades que brinda el proceso docente-educativo, para que aprendan y desarrollen normas de conducta que les permita tener un comportamiento correcto al intervenir en la vía, y una conciencia de responsabilidad ante sus peligros; sin embargo, aún persisten insuficiencias en la preparación y acciones para que este proceso se desarrolle de forma óptima con los estudiantes, pues solo se cuenta con el programa y las orientaciones metodológicas, lo que queda a la creatividad del profesor la elaboración de acciones para lograr este propósito. Se plantea como objetivo: ofrecer una estrategia educativa para dar tratamiento a la educación vial en el proceso de formación inicial del estudiante de la Licenciatura en Educación Preescolar. Se emplearon métodos de investigación científica como el histórico-lógico, analítico-sintético e inductivo-deductivo, que permitieron sintetizar las fuentes más relevantes del tema investigado, así como el desarrollo de la propuesta para su aplicación práctica. Se ofrecen acciones diseñadas desde los componentes académico, laboral, investigativo y extensionista, que propician la identificación afectiva con ellas, y sirve como fundamento de la comprensión de actitudes, hábitos, comportamientos y conductas responsables en la vía pública. Como resultado se demuestra que la propuesta contribuye a la formación vial al favorecer la apropiación del contenido de manera reflexiva y consciente, en una unidad entre la instrucción, la educación y el desarrollo.
Long-term uncertainty quantification in WRF-modeled offshore wind resource off the US Atlantic coast
Authors: Bodini Nicola , Castagneri Simon , Optis Mike 
Published: April 2023

Abstract. Uncertainty quantification of long-term modeled wind speed is essential to ensure stakeholders can best leverage wind resource numerical data sets. Offshore, this need is even stronger given the limited availability of observations of wind speed at heights relevant for wind energy purposes and the resulting heavier relative weight of numerical data sets for wind energy planning and operational projects. In this analysis, we consider the National Renewable Energy Laboratory's 21-year updated numerical offshore data set for the US East Coast and provide a methodological framework to leverage both floating lidar and near-surface buoy observations in the region to quantify uncertainty in the modeled hub-height wind resource. We first show how using a numerical ensemble to quantify the uncertainty in modeled wind speed is insufficient to fully capture the model deviation from real-world observations. Next, we train and validate a random forest to vertically extrapolate near-surface wind speed to hub height using the available short-term lidar data sets in the region. We then apply this model to vertically extrapolate the long-term near-surface buoy wind speed observations to hub height so that they can be directly compared to the long-term numerical data set. We find that the mean 21-year uncertainty in 140 m hourly average wind speed is slightly lower than 3 m s−1 (roughly 30 % of the mean observed wind speed) across the considered region. Atmospheric stability is strictly connected to the modeled wind speed uncertainty, with stable conditions associated with an uncertainty which is, on average, about 20 % larger than the overall mean uncertainty.
RELEVANCE OF SIMPLIFIED TECHNICAL ENGLISH IN KAZAKHSTAN IN THE FIELD OF AVIATION
Authors: Zhandildinova Karlygash , Moldabekov Aidos , Massyukov Bogdan 
Published: April 2023

English is the international language of science and technology. English is not often the first language of technical documentation readers. Most are limited in knowledge of the English language. sentence structure and the large number of meanings and synonyms that many English words possess are complex. Correctly understanding the maintenance and operation documentation is very important in aviation, it also affects the work of safety to protect human lives. The purpose of this article is to highlight the importance of the ASD-STE100 document for students of the Academy of Civil Aviation in Kazakhstan. In this document, we will consider the relevance of applying this document during training in the aviation industry, as well as touch on the requirements for proficiency in technical English and summarize the basic rules aimed at facilitating the study and understanding of the English language.
ПОРТАЛДЫҚ ГИПЕРТЕНЗИЯ (ӘДЕБИ ШОЛУ)
Authors: ТАНАБАЕВА Ш.Б. , АЛМАБАЕВ Ы.А. , АХМАД Н.С. , ФАЗЫЛОВ Т.Р. , КУАНДЫКОВ Е.К. , ФАХРАДИЕВ И.Р. 
Published: April 2023

Портальная гипертензия является следствием повышенного давления воротной вены. Наиболее частой причиной портальной гипертензии является цирроз печени. В этих условиях увеличивается внутрипеченочное сопротивление, что приводит к повышению портального давления. В результате повышенного давления в воротной вене может возникнуть ряд осложнений, в том числе развитие варикозного расширения вен пищевода, желудка, асцит, печеночная энцефалопатия, а также появляется риск развития вторичных осложнений по отношению к дисфункции кровообращения, таких как гепаторенальный синдром, портопульмональный синдром и гепатопульмональный синдром. Увеличивая портальный кровоток, внутренностная вазодилатация еще больше усугубляет гипертензию, устанавливаются новые патогенные пути, которые могут привести к новым терапевтическим стратегиям. В этом обзоре описана классификация портальной гипертензии и ее осложнения. Рассматриваются вопросы диагностики и лечения различных клинических последствий.
Portal hypertension is an important complication of liver diseases. The most common cause of portal hypertension is cirrhosis of the liver. Under these conditions, intrahepatic resistance increases, which leads to an increase in portal pressure. As a result of increased pressure in the portal vein, a number of complications may occur, including the development of varicose veins of the esophagus and stomach, ascites, hepatic encephalopathy, as well as complications secondary to circulatory dysfunction, such as hepatorenal syndrome, portopulmonary syndrome and hepatopulmonary syndrome. By increasing portal blood flow, internal vasodilation further aggravates portal hypertension. New pathogenic pathways are being established that may lead to new therapeutic strategies.This review describes the classification and complications of portal hypertension, as well as some aspects of the diagnosis and treatment of these various important clinical consequences.
Портальды гипертензия бауыр ауруларының маңызды асқынуы болып табылады. Портальды гипертензияның ең көп таралған себебі- бауыр циррозы. Мұндай жағдайларда бауырішілік кедергі артады, бұл қақпа венасындағы қысымының жоғарылауына әкеледі. Қақпа венасындағы жоғары қысымның нәтижесінде бірқатар асқынулар пайда болуы мүмкін, соның ішінде өңеш пен асқазанның варикозды кеңеюі, асцит, бауыр энцефалопатиясы, сондай-ақ қан айналым дисфункциясынан кейінгі асқынулар, мысалы, гепаторенальды синдром, портопульмональды синдром және гепатопульмональды синдром. Қақпа венасындағы қан ағымын жоғарылату, ішкі вазодиляция портальды гипертензияны одан әрі күшейтеді. Осыған орай жаңа терапиялық стратегияға әкелуі мүмкін жаңа патогендік жолдар орнатылуда. Бұл шолуда портальды гипертензияның жіктелуі мен асқынулары, сондай-ақ әртүрлі маңызды клиникалық салдарды диагностикалау мен емдеудің кейбір сәттері сипатталған.