bluuebunny/crossref_metadata_2025_split huggingface dataset:
Are non‐economic goals and financial performance friends or foes in hybrid ventures? A duality perspective on academic spin‐offs
Authors: Minola Tommaso , Hahn Davide , Criaco Giuseppe , Pittino Daniel , Visintin Francesca 
Published: January 2025

AbstractResearch SummaryThis study draws on the behavioral theory of the firm and a duality perspective to investigate the impact of founders' focus on academic goals on the financial performance of academic spin‐offs (ASOs)—a specific type of hybrid venture. We theorize that such relationship follows an inverse U‐shaped curve and is moderated by the degree of academic ownership. These hypotheses are tested using a sample of 179 Italian ASOs. Our findings indicate that when academic ownership is low, the relationship displays an inverted U‐shape. Moreover, as academic ownership increases, the relationship flattens and eventually shifts to a U‐shape. These results challenge the prevailing notion of inherent conflicts between economic and non‐economic logics in hybrid ventures, demonstrating when focusing on non‐economic (e.g., academic) goals enhances financial outcomes.Managerial SummaryAcademic spin‐offs (ASOs) play a pivotal role in science commercialization and often pursue academic goals due to their academic origins. However, the extent to which founders' focus on academic goals benefits or hinders ASOs' financial performance has remained largely underexamined. In this study of 179 Italian ASOs, we investigate the relationship between a focus on academic goals and firm performance. Our findings reveal that at lower levels of academic ownership, a moderate focus on academic goals is optimal for ASOs' financial performance. Conversely, at higher levels of academic ownership, either a low or high focus on academic goals proves optimal for financial performance. These insights can help practitioners improve ASO performance by aligning goal and ownership structures.
Highly Efficient and Stable CsPbI3 Perovskite Quantum Dots Light‐Emitting Diodes Through Synergistic Effect of Halide‐Rich Modulation and Lattice Repair
Authors: Guo Chiyu , Bi Chenghao , Wei Shibo , Ren Ke , Huang Xuexuan , Tao Liang , Wang Xingyu , de Leeuw Nora H. , Wang Wenxin 
Published: January 2025

AbstractCurrently, CsPbI3 quantum dots (QDs) based light‐emitting diodes (LEDs) are not well suited for achieving high efficiency and operational stability due to the binary‐precursor method and purification process, which often results in the nonstoichiometric ratio of Cs/Pb/I. This imbalance leads to amounts of iodine vacancies, inducing severe non‐radiative recombination processes and phase transitions of QDs. Herein, red‐emitting CsPbI3 QDs are reported with excellent optoelectronic properties and stability based on the synergistic effects of halide‐rich modulation passivation and lattice repair. First, a ternary‐precursor method is employed to better control the feed ratio of Cs/Pb/I and create a halide‐rich environment. Second a solvent‐free solid–liquid reaction employing a multifunctional guanidinium iodide (GAI) additive is used after purification to repair iodine vacancies and partially replace surface Cs atoms, thereby effectively modifying its tolerance factor. Additionally, this short‐chain GA+ can be used as the surface ligand to improve the conductivity of the QDs and suppress trap‐assisted non‐radiative Auger recombination. Consequently, PeLEDs based on GAI‐QDs exhibit a great maximum external quantum efficiency (EQE) of 27.1% and an operational half‐lifetime (T50) of 1001.1 min at an initial luminance of 100 cd m−2.
Design of Flavonoid‐Based Lipid Domains as Fusion Inhibitors to Efficiently Block Coronavirus and Other Enveloped Virus Infection
Authors: Dewangan Nikesh , Jana Indrani Das , Yadav Sandeep , Sardar Avijit , Mallick Amirul I. , Mondal Arindam , Tarafdar Pradip K. 
Published: January 2025

AbstractDeveloping a broad‐spectrum antiviral is imperative in light of the recent emergence of recurring viral infections. The critical role of host‐virus attachment and membrane fusion during enveloped virus entry is a suitable target for developing broad‐spectrum antivirals. A new class of flavonoid‐based fusion inhibitors are designed to alter the membrane's physical properties. These flavonoid‐based molecules (MFDA; myristoyl flavonoid di‐aspartic acid) are self‐assembled in the membrane, creating distinct nanodomains and effectively inhibiting membrane fusion by modulating the membrane's interfacial properties. The broad‐spectrum antiviral efficacy of these compounds are established in effectively blocking the entry of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2), Type A Influenza, Human coronavirus OC43 (HCoV‐OC43), and Vesicular stomatitis virus (VSV). A slightly more effectivity of MFDA in coronavirus infection than other enveloped viruses may be attributed to its secondary interaction with the receptor binding domain (RBD) of the SARS‐CoV‐2 spike protein. A membrane nanodomain formation strategy is highlighted with natural‐product‐based fusion inhibitors, effectively thwarting the infection of several enveloped viruses, entailing their broad‐spectrum antiviral functionality.
Recent Advances in Fast‐Charging Sodium‐Ion Batteries
Authors: Chen Yiqing , Yan Shimin , Chen Long , Zhao Dong , Ding Yan , Zeng Yubin , Chen Zhongxue 
Published: January 2025

AbstractSodium‐ion batteries (SIB), stemming from the abundance of sodium resources and their cost‐effectiveness, have positioning them favorably a potential candidate for stationary energy storage and public electric vehicles. As an intermediary of the grid system and output terminals of the charging station, fast‐charging performance has actually become a crucial metric, which greatly relates to the charging station utilization and cost‐ and time‐efficient. Besides, the fast‐charging capacity is also relevant to the long‐term stable operation public transportation. Given the remarkable advancements in fast‐charging SIBs reported recently, a review about this topic and scope is timely and important at present. In this study, the bottlenecks of fast‐charging SIBs are first assessed, after that, a comprehensive overview of the employed strategies for improving the fast‐charging capacities of SIBs from three aspects: structures design, reaction mechanism regulation, and optimization of solvation structure and interfacial property is given. Finally, challenges and prospects for further research toward fast‐charging SIBs are proposed. The authors hope this review will provide a deep understanding of the design principles of fast‐charging SIBs and inspire more endeavors to conquer the practicability issue of SIBs in energy storage fields.
Addressing media and information literacy in engineering design education: Learning to design technologies in the era of science denial and misinformation
Authors: Pérez Greses , Henderson Trevion , Wendell Kristen B. 
Published: January 2025

AbstractEngineering design entails making value‐laden judgments against ill‐defined, ambiguous, and/or competing sociotechnical criteria. In this article, we argue that such conditions make engineering designers particularly susceptible to the potentially deleterious effects of mis/disinformation in the processes and practices of engineering design, their engagement with people and communities, and in the production and evaluations of the artifacts they produce. We begin by critiquing dominant approaches to engineering design education, specifically, engineering education's social‐technical dualism and the ubiquitous ideology of depoliticization, which has exacerbated the effects of mis/disinformation in engineering design. We follow by outlining a framework for developing students' capacity for mitigating its effects in the specific context of engineering design thinking and making value‐laden engineering judgments and decision‐making. We envision three areas of opportunity for engineering design education to teach students strategies for navigating these challenges when engaging with (a) the processes and practices of engineering, which reflect the unique types of information students engage with across the design process, (b) people and their communities, including the strategic and careful performance of activities for gathering information, while mitigating the harms to misinformation and disinformation and maximizing the benefits of community involvement, and (c) the social and technical criteria of engineering design outcomes in the form of artifacts (e.g., products, processes).
CBL and Its Evolution as an Instructional and Pedagogical Practice
Authors: Dikilitaş Kenan , Marshall Tim , Shahverdi Masoumeh 
Published: January 2025

Abstract
This chapter provides a short overview of the history of Challenge-Based Learning (CBK) and its evolution as a pedagogical practice in higher education. We discuss how CBL reshapes pedagogical approaches to learning and teaching as well as student engagement and self-directed learning in collaborative practices. The vignette included compares CBL to other experiential learning methods such as problem-based and project-based learning. The chapter then discusses CBL's origins in both bioengineering at a higher education level and the Apple pilots at a high school level, both in the USA.
CBL Assessment, Feedback, and Evaluation
Authors: Dikilitaş Kenan , Marshall Tim , Shahverdi Masoumeh 
Published: January 2025

Abstract
This chapter presents a comprehensive, practical guide to assessment, feedback, and evaluation in CBL for teachers and practitioners to use. It takes a detailed look at formative and informative methods of assessment and how it can be done in both informal and formal ways. For feedback, it looks at how this is given by all parties in CBL; teachers and practitioners, students, and external stakeholders to ensure a multi-directional learning process. It also examines how to evaluate the successful use of CBL and how to balance this with traditional evaluation methods. It offers practical tips for practitioners throughout the chapter and examples of conversations that illustrate how to conduct effective feedback sessions before concluding with a vignette giving real examples of CBL assessment and evaluation in two courses at Prague University of Economics and Business.
CBL Micro-Level Frame Case Studies
Authors: Dikilitaş Kenan , Marshall Tim , Shahverdi Masoumeh 
Published: January 2025

Abstract
This Chapter contains five micro-level case studies that examine CBL within specific educational practices, for example, within a particular academic discipline. Case Study One explores CBL used in the master's level course Information Management and Digitalization at UiS. Case Study Two presents an innovative approach to learning dubbed “An inGenious Way of Learning,” at Linköping University, alongside a parallel implementation at the University of Stavanger. Case Study Three, also at Linköping University, details the application of CBL in sustainability education. Case Study Four showcases the implementation of CBL in a multidisciplinary integrated project at the Universidad de Sevilla. Finally, Case Study Five, again from Linköping University, explores the integration of CBL in Project Management and Organisation studies.
CBL Meso-Level Frame Case Studies
Authors: Dikilitaş Kenan , Marshall Tim , Shahverdi Masoumeh 
Published: January 2025

Abstract
This chapter contains five meso-level case studies that examine CBL outside of specific educational practices such as extra-curricular CBL implementation with a particular focus on the role of external stakeholders. Case Study Six, from the University of Trento, examines the extra-curricular Alpine Smart Working Challenge, which partners with the local innovation hub. Case Study Seven from Universitat Autònoma de Barcelona details the co-creation of a CBL challenge with local stakeholders. Case Study Eight, a collaboration between Hamburg University of Technology and the University of Twente, investigates the integration of CBL with the writing of a master’s thesis through the pilot of the ECIU strategic challenge. Case Study Nine, from Kaunas University of Technology, explores the utilisation of CBL in a specific extra-curricular model focusing on innovation in CBL. Finally, Case Study Ten presents the unique implementation of CBL in a non-educational context, in a specially designed CBL programme for communications staff at the University of Stavanger.
CBL Future Implications for Teachers, Practitioners, Students, and Stakeholders
Authors: Dikilitaş Kenan , Marshall Tim , Shahverdi Masoumeh 
Published: January 2025

Abstract
This chapter is an exploration of the multi-faceted implications of future CBL implementation for teachers, practitioners, students, and external stakeholders through a close reading of the case studies within the three levels of the ecological framework including micro, meso, and macro. This analysis draws on the details of these CBL implementations in different disciplines and in different ways to reveal contextualised practices and understandings that shape an emerging set of practical implications for those who would like to implement CBL.
CBL Conversations with Colleagues and Students
Authors: Dikilitaş Kenan , Marshall Tim , Shahverdi Masoumeh 
Published: January 2025

Abstract
This chapter gives a direct voice to CBL experiences through transcripts of interviews with colleagues and students shaping the narrative around the implementation of CBL. These conversations are both one-to-one interviews conducted on Teams and a questionnaire answered via Microsoft Forms. Themes discussed throughout the book in earlier chapters are revisited, offering a nuanced perspective on the transformative potential of CBL. Readers are also invited to reflect on questions specific to each interview that can enhance their own teaching practice of CBL.
AIXE. A Method to Evaluate the UX of Systems Integrating AI
Authors: Spallazzo Davide , Sciannamè Martina , Ceconello Mauro 
Published: January 2025

Abstract
The chapter frames the AIXE (AI user eXperience Evaluation) scale, a statistically validated questionnaire to assess the UX of AI-infused products, describing its development process as well as its validation. AIXE is composed by 33 questions with 4 ordinal Likert-scale answers, organized around 12 descriptors related to the UX of the target systems. The questionnaire is meant to be proposed to the intended users of AI-infused products to quantitatively analyse the user experience they convey. The chapter further illustrates how the scale can be applied, its limitations and future opportunities.
Der Einfluss räumlicher Ungleichheit auf nachhaltige Alltagsmobilität am Beispiel formal Höhergebildeter
Authors: George Sarah , Salomo Katja 
Published: January 2025

Zusammenfassung
Um den Klimawandel effektiv zu bekämpfen, ist es von großer Bedeutung, die Bevölkerung zu umweltfreundlichem Verhalten zu motivieren. Dies schließt die Alltagsmobilität ein. Sie zählt zu den größten Quellen von Treibhausgasemissionen. Bisherige Forschungsergebnisse deuten darauf hin, dass Personen mit höherem Bildungsniveau tendenziell umweltfreundlichere Mobilitätsmuster aufweisen, was in der Regel mit einem stärkeren Umweltbewusstsein erklärt wird. Wir untersuchen, inwieweit diese Verhaltensweisen durch sozial-räumliche Faktoren beeinflusst werden. Zum anderen gehen wir belastbaren Hinweisen auf Verhaltensänderungen zugunsten klimaschonender Mobilität nach. Dazu verwenden wir Daten zur Alltagsmobilität aus den Jahren 2002 und 2017, die eine repräsentative Stichprobe der deutschen Bevölkerung im Alter von 18 bis 65 Jahren umfassen. Mithilfe von Mehrebenen-OLS- und logistischen Regressionen sowie fractional multinomial logit-Modellen analysieren wir Veränderungen im Mobilitätsverhalten von Personen mit hohem Bildungsniveau über die Zeit. Unsere Ergebnisse zeigen, dass Hochschulabsolventen nicht nur häufiger in Metropolregionen leben, sondern auch in den zentralen Vierteln dieser Regionen, was zu kürzeren täglichen Pendelstrecken führt. Folglich benötigen sie weniger Reisezeit und können langsamere und nachhaltigere Verkehrsmittel für ihre Arbeitswege, Besorgungen und Freizeitaktivitäten nutzen, ohne dabei höhere Zeitkosten für ihre Alltagsmobilität als andere soziale Gruppen zu haben. Diese Ergebnisse unterstreichen die Notwendigkeit, sozial-räumliche Ungleichheiten zu bekämpfen, um einer breiteren Bevölkerung einen nachhaltigen Lebensstil zu ermöglichen.
Wie verändern Hybrid-DRGs („diagnosis related groups“) die deutsche Urologie?
Authors: Reimold Philipp , Groeben Christer , Borkowetz Angelika , Eisenmenger Nicole , König Frank , Leitsmann Marianne , Witzsch Ulrich , Müller Markus , Schöne Markus , Schultz-Lampel Daniela , Fisch Margit , Kollenbach Peter , Schneider Andreas , Westphal Jens , Borchers Holger , Belusa Axel , Michel Maurice Stephan , Volkmer Björn , Huber Johannes 
Published: January 2025

Zusammenfassung

Hintergrund
Mit der Einführung der Hybrid-DRG („diagnosis related groups“) zum 01.01.2024 sollen Anreize geschaffen werden, bisher stationär erbrachte Leistungen in der Urologie, beispielsweise die Ureterorenoskopie (URS), ambulant durchzuführen und sektorengleich zu vergüten. Die Auswirkungen auf die Versorgungsrealität sind derzeit unklar.

Fragestellung
Ziel der Umfrage war es, ein Stimmungsbild zur Einführung der Hybrid-DRG in der Urologie zu erfassen und erste praktische Erfahrungen sowie zukünftige Perspektiven zu beleuchten.

Material und Methoden
In einer deutschlandweiten Online-Umfrage im Zeitraum Mai bis Juli 2024 wurden 32 Fragen u. a. zur Patientenversorgung, Weiterbildung und weiteren Indikationen gestellt. Zudem wurde eine Einschätzung des ambulanten Potenzials für URS bei Harnleiter- und Nierensteinen sowie Hydrozelenresektionen erfragt.

Ergebnisse
Insgesamt beantworteten 364 Urologinnen und Urologen die Umfrage. 54,5 % waren niedergelassen, 45,5 % in Kliniken tätig. 91,1 % waren operativ aktiv. Das Konzept der Hybrid-DRG wurde von 34 % der operativ Tätigen positiv bewertet, jedoch sahen 68 % keine Erleichterung für den Alltag. 51 % äußerten Bedenken hinsichtlich der negativen Auswirkungen auf die Weiterbildung. Der Anteil der 2023 ambulant erbrachten URS lag bei 21 % (Harnleitersteine) und 11 % (Nierensteine) mit langfristigem Steigerungspotenzial von bis zu 33 %. Hydrozelenresektionen wurden bereits zu zwei Dritteln ambulant durchgeführt, und 74 % der Befragten hielten diesen Eingriff für in einer Hybrid-DRG abrechenbar.

Schlussfolgerung
Die Umfrage zeigt ein differenziertes Meinungsbild zu den Hybrid-DRG in der Urologie, jedoch umfasst die Stichprobe nur etwa 6 % der Urologen in Deutschland und Chefärztinnen und Chefärzte sind überrepräsentiert. Eine Wiederholung der Umfrage zu einem späteren Zeitpunkt wäre sinnvoll, um die Entwicklungen im praktischen Einsatz zu evaluieren.

Graphic abstract
Derandomized Truncated D-vine Copula Knockoffs with e-values to control the false discovery rate
Authors: Vásquez Alejandro Román , Márquez Urbina José Ulises , González Farías Graciela , Escarela Gabriel 
Published: January 2025

Abstract
The Model-X knockoffs is a practical methodology for variable selection, which stands out from other selection strategies since it allows for the control of the false discovery rate, relying on finite-sample guarantees. In this article, we propose a Truncated D-vine Copula Knockoffs (TDCK) algorithm for sampling approximate knockoffs from complex multivariate distributions. Our algorithm enhances and improves features of previous attempts to sample knockoffs under the multivariate setting, with the three main contributions being: (1) the truncation of the D-vine copula, which reduces the dependence between the original variables and their corresponding knockoffs, thus improving the statistical power; (2) the employment of a straightforward non-parametric formulation for marginal transformations, eliminating the need for a specific parametric family or a kernel density estimator; (3) the use of the “rvinecopulib” R package offers better flexibility than the existing fitting vine copula knockoff methods. To eliminate the randomness from the different sets of selected variables in distinct realizations, we wrap the TDCK method with an existing derandomizing procedure for knockoffs, leading to a Derandomized Truncated D-vine Copula Knockoffs with e-values (DTDCKe) procedure. We demonstrate the robustness of the DTDCKe procedure under various scenarios with extensive simulation studies. We further illustrate its efficacy using a gene expression dataset, showing it achieves a more reliable gene selection than other competing methods when the findings are compared with those of a meta-analysis. The results indicate that our Truncated D-vine copula approach is robust and has superior power, representing an appealing approach for variable selection in different multivariate applications, particularly in gene expression analysis.
Value of endometrial biopsy in patients with hysteroscopically atrophic endometrium in patients with postmenopausal bleeding
Authors: Ashmore Ayisha A. , Alao Abayomi I. , Hibbard Amie , Burchnall Libbi , Menic Natalie , Abdul Summi , Asher Viren , Bali Anish , Kolhe Shilpa , Phillips Andrew 
Published: January 2025

Abstract

Purpose
To determine the rate of precancer and cancer in women presenting with PMB who have a visually atrophic endometrium at hysteroscopy and assess the value of endometrial biopsy in this situation and the adequacy of the samples obtained.

Methods
Retrospective reviews of all patients with a visually atrophic endometrium at hysteroscopy who had presented with PMB and had an ET > / = 4 mm or ET < 4 mm with focal changes or irregular features between 2013 and 2024 at University Hospitals of Derby and Burton were included (n = 1096). Patients who had previously had cancer or precancer or had unclear hysteroscopy findings were excluded. The endometrial biopsy histology result was considered the main outcome measure.

Results
188 patients did not have a biopsy performed (17.15%), 660 patients had benign pathology (60.22%), and 239 patients had an inadequate sample result (21.81%). Nine patients had precancerous changes (0.82%). The rate of cancer was 0.00% (n = 0). The NPV of a visually atrophic endometrial cavity at hysteroscopy in detecting precancer or cancer was 99.2%. Patients with an ET < 4 mm pre-hysteroscopy and an atrophic endometrial cavity at hysteroscopy were 2.25 times more likely than those whose ET is > 4 mm to have an inadequate sample (p < 0.001, 95% CI 1.61–3.16). 10 patients who had an inadequate sample at initial biopsy had a repeat inadequate sample (n = 23, 43.48%).

Conclusions
The incidence of precancer/cancer in patients presenting with PMB with a visually atrophic endometrium at hysteroscopy is low. Many patients within this cohort have an inadequate sample at biopsy, and therefore, repeat sampling is of questionable value.