bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mental health and its influencing factors of maintenance hemodialysis patients: a semi-structured interview study
Authors: Wen Junjun , Fang Yuan , Su Zhongyan , Cai Jimin , Chen Zhiyan 
Published: March 2023

Abstract
Background
Maintenance hemodialysis (MHD) is a commonly used renal replacement therapy for end-stage renal disease patients. MHD patients have undergone multiple physiological stressors, which may cause physical problems and affect their mental health; however, few qualitative studies have been done on the mental health of MHD patients. Such qualitative research becomes the basis for further quantitative research and is critical to validating its results. Therefore, the current qualitative study used a semi-structured interview format, and aimed to explore the mental health and its influencing factors of MHD patients who are not receiving intervention treatment to determine how best to ameliorate their mental health.

Methods
Based on the application of Grounded Theory, semi-structured face-to-face interviews were conducted with 35 MHD patients, following consolidated criteria for reporting qualitative studies (COREQ) guidelines. Two indicators (emotional state and well-being) were used to assess MHD patients’ mental health. All interviews were recorded, after which two researchers independently performed data analyses using NVivo.

Results
Acceptance of disease, complications, stress and coping styles, and social support were found to be the influencing factors of MHD patients’ mental health. High acceptance of disease, healthy coping styles, and high social support were positively correlated with mental health. In contrast, low acceptance of disease, multiple complications, increased stress, and unhealthy coping styles were negatively correlated with mental health.

Conclusion
One’s acceptance of the disease played a more significant role than other factors in affecting MHD patients’ mental health.
Homogeneity and heterogeneity in near-infrared FTIR spectra of Ryugu returned samples
Authors: Hatakeda Kentaro , Yada Toru , Abe Masanao , Okada Tatsuaki , Nakato Aiko , Yogata Kasumi , Miyazaki Akiko , Kumagai Kazuya , Nishimura Masahiro , Hitomi Yuya , Soejima Hiromichi , Nagashima Kana , Yoshitake Miwa , Iwamae Ayako , Furuya Shizuho , Usui Tomohiro , Kitazato Kohei 
Published: March 2023

AbstractSurface and subsurface materials of C-type near-Earth asteroid 162173 Ryugu were collected and successfully returned to the Earth in the Hayabusa2 mission. Fourier Transform Infrared Spectroscopy (FTIR) has been conducted to characterize these returned samples as one of the initial descriptions in a non-destructive manner under a purified nitrogen condition without terrestrial contamination. We selected the individual grains and aggregate samples that were not severely influenced by the reflection of incident beam at the sapphire dish and analyzed their reflectance spectra using the primary component analysis (PCA). The result indicates that Ryugu returned samples are highly homogeneous with only a little heterogeneity. The average spectrum of the main PCA group is represented by four absorption bands at 2.7, 3.05, 3.4, and 3.95 μm. The spectral feature is consistent with that obtained from bulk FTIR measurements, indicating potential presence of hydroxyl, organics, and carbonates. Rarely observed types of grains with unique spectra are categorized into three groups: significantly high reflectance, carbonates, and hydroxyl compounds with broad OH absorption.
Graphical Abstract
Income and rural–urban status moderate the association between income inequality and life expectancy in US census tracts
Authors: Cohen Steven A. , Nash Caitlin C. , Byrne Erin N. , Greaney Mary L. 
Published: March 2023

Abstract
Background
A preponderance of evidence suggests that higher income inequality is associated with poorer population health, yet recent research suggests that this association may vary based on other social determinants, such as socioeconomic status (SES) and other geographic factors, such as rural–urban status. The objective of this empirical study was to assess the potential for SES and rural–urban status to moderate the association between income inequality and life expectancy (LE) at the census-tract level.

Methods
Census-tract LE values for 2010–2015 were abstracted from the US Small-area Life Expectancy Estimates Project and linked by census tract to Gini index, a summary measure of income inequality, median household income, and population density for all US census tracts with non-zero populations (n = 66,857). Partial correlation and multivariable linear regression modeling was used to examine the association between Gini index and LE using stratification by median household income and interaction terms to assess statistical significance.

Results
In the four lowest quintiles of income in the four most rural quintiles of census tracts, the associations between LE and Gini index were significant and negative (p between < 0.001 and 0.021). In contrast, the associations between LE and Gini index were significant and positive for the census tracts in the highest income quintiles, regardless of rural–urban status.

Conclusion
The magnitude and direction of the association between income inequality and population health depend upon area-level income and, to a lesser extent, on rural–urban status. The rationale behind these unexpected findings remains unclear. Further research is needed to understand the mechanisms driving these patterns.
Identification of an inhibitor for atherosclerotic enzyme NOX-1 to inhibit ROS production
Authors: Ganguly Rik , Ngoruh Angneh , Ingty Prosperwell , Yadav Shashi Kumar , Bhattacharjee Atanu 
Published: March 2023

Abstract
Background
NOX-1 overexpression has been observed in various studies, persons with diabetes or cardiovascular conditions. NOX-1 orchestrates the disease pathogenesis of various cardiovascular conditions such as atherosclerotic plaque development and is a very crucial biomarker. Therefore, this study was carried out to deduce the three-dimensional modelled structure of NOX-1 using DeepMind AlphaFold-2 to find meaningful insight into the structural biology. Extensive in silico approaches have been used to determine the active pocket, virtually screen large chemical space to identify potential inhibitors. The role of the key amino acid residues was also deduced using alanine scanning mutagenesis contributing to the catalytic process and to the overall stability of NOX-1.

Results
The modelled structure of NOX-1 protein was validated using ERRAT. The ERRAT statistics with 9 amino acids sliding window have shown a confidence score of 96.937%. According to the Ramachandran statistics, 96.60% of the residues lie within the most favoured region, and 2.80% of residues lie in the additionally allowed region, which gives an overall of 99.4% residues in the three quadrants in the plot. GKT-831 which is a referral drug in this study has shown a GOLD interaction score of 62.12 with respect to the lead molecule zinc000059139266 which has shown a higher GOLD score of 78.07. Alanine scanning mutagenesis studies has shown that Phe201, Leu98 and Leu76 are found to be the key interacting residues in hydrophobic interactions. Similarly, Tyr324, Arg287 and Cys73 are major amino acid residues in the hydrogen bond interactions.

Conclusions
NOX-1 overexpression leads to heightened ROS production resulting in catastrophic outcomes. The modelled structure of NOX-1 has a good stereochemistry with respect to Ramachandran plot. The lead molecule zinc000059139266 has shown to have a very high interaction score of 78.07 compared to the referral drug GKT-831 with a score of 62.12. There is an excellent scope for the lead molecule to progress further into in vitro and in vivo studies.
Pulmonary artery reconstruction using a pulmonary vein conduit in case having an imbalanced dissection length during double-sleeve lobectomy
Authors: Fujiwara Toshiya , Okada Kazuhiro , Hirano Yutaka , Maki Yuho , Saiki Munehiro , Yunoki Keiji , Matsuura Motoki 
Published: March 2023

Abstract
Background
Among the types of lung resection procedures, pneumonectomy carries the highest risk for mortality. In recent years, bronchovascular double-sleeve lobectomy has been performed for centrally located non-small cell lung cancer involving both the bronchus and the pulmonary artery (PA) in order to avoid pneumonectomy. The use of an autologous pulmonary vein (PV) conduit for PA reconstruction during lung-sparing resections had first been reported in 2009. Such situations may occur in cases requiring the resection of a long segment of the PA without associated bronchial sleeve resection.

Case presentation
We experienced two cases who underwent PA reconstruction using a PV conduit after double-sleeve resection. In both cases, the tumor was located in the left upper lobe and invaded the long segment of the PA; however, it had not significantly invaded the bronchus. Our strategy for bronchovascular reconstruction involved the use of a PV conduit to avoid high tension on direct anastomosis given the imbalance in the excision length between the PA and the bronchus. The intraoperative and postoperative courses were uneventful, with both cases not receiving anticoagulant agents during the postoperative period. The reconstructed bronchus and PA functioned well during postoperative follow-up visits.

Conclusions
Following sleeve resection, an autologous PV conduit may be indicated for PA reconstruction when an excessive distance exists between the two vascular stumps.
Assessment of Tribo-charging and Continuous Feeding Performance of Direct Compression Grades of Isomalt and Mannitol Powders
Authors: Beretta Michela , Kruisz Julia , Hörmann-Kincses Theresa R. , Magosi Viktoria , Guo Meishan , Naderi Majid , Heupl Sarah , Kastner Johann , Spoerk Martin , Paudel Amrit 
Published: March 2023

Abstract
Tribo-charging is often a root cause of mass flow deviations and powder adhesion during continuous feeding. Thus, it may critically impact product quality. In this study, we characterized the volumetric (split- and pre-blend) feeding behavior and process-induced charge of two direct compression grades of polyols, galenIQ™ 721 (G721) for isomalt and PEARLITOL® 200SD (P200SD) for mannitol, under different processing conditions. The feeding mass flow range and variability, hopper end fill level, and powder adhesion were profiled. The feeding-induced tribo-charging was measured using a Faraday cup. Both materials were comprehensively characterized for relevant powder properties, and their tribo-charging was investigated for its dependence on particle size and relative humidity. During split-feeding experiments, G721 showed a comparable feeding performance to P200SD with lower tribo-charging and adhesion to the screw outlet of the feeder. Depending on the processing condition, the charge density of G721 ranged from -0.01 up to -0.39 nC/g, and for P200SD from -3.19 up to -5.99 nC/g. Rather than differences in the particle size distribution of the two materials, their distinct surface and structural characteristics were found as the main factors affecting their tribo-charging. The good feeding performance of both polyol grades was also maintained during pre-blend feeding, where reduced tribo-charging and adhesion propensity was observed for P200SD (decreasing from -5.27 to -0.17 nC/g under the same feeding settings). Here, it is proposed that the mitigation of tribo-charging occurs due to a particle size-driven mechanism.
Graphical abstract
Lasing features of the ultra-short Fabry–Perot cavity on the basis of a photosensitive Er/Yb-doped multimaterial fiber with a silicophosphate core
Authors: Rybaltovsky A. A. , Bazakutsa A. P. , Denker B. I. , Egorova O. N. , Sverchkov S. E. , Velmiskin V. V. 
Published: March 2023

The lasing properties of a short-cavity laser based on the Er/Yb composite fiber with a silicophosphate core in a silica cladding were investigated in detail. A Fabry–Perot cavity was manufactured on a 25 mm long fiber segment using the ultraviolet (UV) (λ=193nm) excimer laser radiation and phase-mask technique of Bragg grating inscription. The laser with an effective cavity length of 11 mm generated single-frequency radiation centered at 1554.45 nm. This laser demonstrated strictly continuous-wave operation under 974 nm pumping but self-Q-switched operation under 1485 nm pumping. Under 974 nm pumping, the slope efficiency was as high as 4%, and the output power reached 17 mW—a level comparable with the characteristics of commercial single-frequency laser diodes.
Validation of web-based audiometry version of HEARZAP
Authors: P. Pandi Renganath , Ramkumar Vidya 
Published: March 2023

Aim
The purpose of this study was to verify the accuracy of the web-based audiometer HEARZAP in determining hearing thresholds for both air and bone conduction.

Method
Using a cross-sectional validation design, the web-based audiometer was compared to a gold standard audiometer. Participants in the study totaled 50 (100 ears), of which 25 (50 ears) had normal hearing sensitivity and 25 (50 ears) had various types and degrees of hearing loss. All subjects underwent pure tone audiometry, including air and bone conduction thresholds, using the web-based and gold standard audiometers in a random order. A pause between the two tests was allowed if the patient felt comfortable. The testing for the web-based audiometer and gold standard audiometer was done by two different audiologists with similar qualifications in order to eliminate tester bias. Both the procedures were performed in a sound treated room.

Results
For air conduction thresholds and bone conduction thresholds, respectively, the mean discrepancies between the web-based audiometer and the gold standard audiometer were 1.22 dB HL (SD = 4.61) and 0.8 dB HL (SD = 4.1). The ICC for air conduction thresholds between the two techniques was 0.94 and for the bone conduction thresholds was 0.91. The Bland Altman plots likewise indicated excellent reliability between the two measurements, with the mean difference between the HEARZAP and the gold standard audiometry falling within the top and lower limits of agreement.

Conclusion
The web-based audiometry version of HEARZAP produced precise findings for hearing thresholds that were comparable to those obtained from an established gold standard audiometer. HEARZAP, has the potential to support multi-clinic functionality and enhance service access.
ADOECIMENTO MENTAL EM ENFERMEIROS ATUANTES NA ASSISTÊNCIA AOS PACIENTES COM COVID-19
Authors: Silva Williane de Oliveira , Symara Abrantes  Albuquerque de Oliveira Cabral  
Published: March 2023

Resumo: Introdução: Em março de 2020, foi declarada, pela Organização Mundial de Saúde, a pandemia pelo vírus SARS-Cov-2, causador da doença Covid-19. O vírus apresenta alta taxa de transmissão, e é responsável por uma infecção viral, pela qual uma porcentagem importante de indivíduos acometidos irão necessitar de uma assistência hospitalar especializada. Objetivos: Analisar através de uma revisão sistemática, o impacto da pandemia por COVID-19 na saúde mental dos profissionais enfermeiros atuantes nos serviços assistenciais de saúde. Metodologia: Trata-se de uma revisão integrativa da literatura, método que apresenta uma abordagem ampla de sistematização de evidências, na qual é possível incluir uma diversidade maior de estudos, envolvendo pesquisas e revisões. Resultados: após análise dos dados foram selecionados 16 artigos para o estudo final. Conclusões: Muitos fatores influenciaram para o adoecimento mental dos enfermeiros. Diante disso, é claro que os profissionais que exercem o cuidar de outros indivíduos também necessitam de cuidados e estratégias que prezem pela sua saúde mental e física, pois muitos profissionais encontram-se esgotados, com quadros depressivos, de ansiedade e medo em escala mundial, em decorrência da sobrecarga em decorrência da pandemia pelo novo coronavírus.

Palavras-Chave: Saúde Mental, Profissionais de Enfermagem, Covid-19
Enseigner la lecture au primaire et au secondaire au primaire et au secondaire : quelles opérations de lecture, quels types de textes et quels gestes professionnels ?
Authors: Libion Morgane , Mahieu Luc , Pénillon Élodie 
Published: March 2023

Le présent article vise à revenir sur les neuf séances d’analyse collaborative de pratiques d’enseignement de la lecture aux différents niveaux de la scolarité menées par le groupe de recherche CRIPEDIS (Centre de recherche interdisciplinaire sur les pratiques enseignantes et les disciplines scolaires) français dirigé par Jean-Louis Dufays et rassemblant des chercheurs et enseignants de différentes institutions en Fédération Wallonie-Bruxelles. Ce travail vise à valider et affiner l’usage de trois grilles d’analyse (les gestes professionnels, les schèmes et les opérations de lecture) en vue d’en faire des instruments d'(auto)évaluation des pratiques à destinations des formateurs et des enseignants. Ainsi, nous souhaitons observer dans quelle mesure il est possible d’en dégager d’une part une typologie des objectifs des leçons en termes d’opérations de lecture et de choix de texte, et d’autre part une distribution signifiante des gestes professionnels et didactiques, et des schèmes d’action transversaux mis en œuvre dans les différents cas de figure et selon les niveaux d’âge. Au terme de notre analyse, nous mettons en évidence une typologie des objectifs des leçons en termes d’opérations de lecture et de choix de texte, avec une progressivité de la compréhension vers l’interprétation et l’absence de l’appréciation. Concernant les gestes professionnels, des spécificités liées aux niveaux d’âge n’ont pu être observées au sein de notre corpus, ce qui indique peut-être qu’il existe une couverture généralisée des 21 gestes indépendamment des niveaux d’âge établissant alors le caractère curriculaire de la grille d’analyse.
éveil aux langues en Belgique francophone
Authors: Herbinaux Nadège , Van de Vyver Julie , Anckaert Philippe , Meunier Fanny 
Published: March 2023

Dans le cadre des travaux du Pacte pour un enseignement d’excellence en Fédération Wallonie-Bruxelles (FWB), l'éveil aux langues (EAL) a été ajouté au programme des élèves en maternelle depuis septembre 2020. Selon les « Balises de progression de l’éveil aux langues » (Fédération Wallonie-Bruxelles, 2020), les objectifs de sensibilisation et de prise de conscience de phénomènes langagiers impliquent de développer des attitudes d’ouverture à la diversité linguistique et culturelle, de renforcer l’intérêt pour les langues et d’assurer le développement de savoirs relatifs aux langues. Divers projets de recherche de grande ampleur abordant l’EAL ont été menés en Europe, mais la situation en FWB n’a pas encore fait l’objet d’études spécifiques.
Notre recherche met en perspective les visées théoriques de l’EAL (inspirées de Candelier, 2008) et les pratiques enseignantes observées dans quatre classes de maternelle via deux questions de recherche : (1) Les pratiques observées rencontrent-elles les objectifs poursuivis par le document de référence Balises ? (2) Quels sont les freins et difficultés rencontrés dans la mise en œuvre de l’EAL en FWB ?
Les pratiques déclarées récoltées lors d’entretiens semi-dirigés et l’observation des pratiques en classe ont permis l’analyse de la mise en œuvre de l'EAL. En nous basant sur le modèle ouvert de l’analyse de contenu qualitative (L'Écuyer,1990), nous avons identifié des catégories d’informations à partir des données brutes. La grille d’analyse nous permet de dresser une classification finale des freins et difficultés et ainsi de dégager des pistes d’amélioration de l’accompagnement des nouveaux acteurs de l’EAL.
Assessing strategies for enhancing the integration of cultural practices in teaching and learning of chemistry in secondary schools
Authors: Achimugu Lawrence , Fasanya Ayodele Gabriel , Abdulwaheed Ibrahim Opeyemi , Joshua Abel Okpanachi , Ibrahim Samuel , Shaibu Abimaje Etimane 
Published: March 2023

Abstract
The purpose of the study was to assess strategies for enhancing the integration of cultural practices into the teaching and learning of chemistry in secondary schools. The study adopted a descriptive survey research design and the population of the study comprised 19,920 respondents. Two research questions and two hypotheses guided the study. The instrument used for data collection was “Strategies Enhancing Integrating Cultural Practices Questionnaire (SEICPQ)” developed by the researchers. Mean and standard deviation were used to answer the research questions and t-test statistic was used to test the null hypotheses at 0.05 significance. The result revealed that incorporation of cultural practices into the chemistry curriculum content and adequate training of teachers on the integration of cultural practices in teaching chemistry and among others were identified as strategies that could enhance the integration of cultural practices. Non-incorporation of cultural practices into the chemistry curriculum content among others were identified as factors affecting the integration of cultural practices. The results also revealed that teachers and students do not significantly differ on their responses on strategies enhancing as well as the factors militating against the integration of cultural knowledge and practices into teaching of chemistry. Necessary conclusions were made.
Development, physiochemical and sensory evaluation of a new effervescent tablet formulation based on Moringa oleifera leaves extract
Authors: Iwansyah Ade Chandra , Fauzi Hilman , Cahyadi Wisnu , Hariadi Hari , Indriati Ashri , Wardhani Riuh , Abd Hamid Hazrulrizawati 
Published: March 2023

Abstract
New product development of Moringa oleifera effervescent tablet was optimization of the acid-base in the formula by using the D-optimal mix design. Chemical profiling and antioxidant activity of Moringa oleifera extract was evaluated. The physicochemical and sensory characteristics of Moringa oleifera effervescent tablet was measured. The results shows that chemical compounds of aqueous and ethanol extracts of Moringa oleifera extracts were hydrocarbons, esters, alcohols, and fatty acids. Both extracts exhibited high antioxidant by the IC50 value at 240.27 μg/mL and 301.21 μg/mL respectively. The quadratic model was found to be the best fitted for evaluating the solubility time, colour, taste and aroma; meanwhile, the special cubic model appeared to be the best fitting model for assessing the hardness response. The optimization process suggested that citric acid (22.19% w/w), tartaric acid (11.17% w/w), and sodium bicarbonate (33.64% w/w) was the best solution for this combination of variables, with a desirability value of 0.798.
Text World Theory and situation-model research: enhancing validity and tracking world-retrievals
Authors: Gibbons Alison 
Published: March 2023

Abstract
When Paul Werth invented the concept of ‘text-worlds’ (1999), he drew on existing psychological accounts of how the mind processes stimuli, such as the idea of the ‘situation model’ (van Dijk and Kintsch 1983). Yet despite the important advancements to Werth’s approach that have been made in stylistics over the years, situation-model research is rarely, if ever, referenced in what is now called Text World Theory (Gavins 2007). In this article, I consult empirical research on situation models, consequently making two significant contributions: I show how empirical situation-model research bolsters the validity of Text World Theory; I propose a new concept for Text World Theory—‘world-retrieval’—to account for how readers trace the interconnections between text-worlds and attempt to resolve processing difficulties. An analysis of the opening to Ray Loriga’s (2003) novel Tokyo Doesn’t Love Us Anymore demonstrates the value of the ‘world-retrieval’ concept.