bluuebunny/crossref_metadata_2025_split huggingface dataset:
Polyphenols for Preventing Dental Erosion in Pre-clinical Studies with in situ Designs and Simulated Acid Attack
Authors: Leal Isabelly de Carvalho , Rabelo Cibele Sales , de Melo Mary Anne Sampaio , Silva Paulo Goberlânio de Barros , Costa Fábio Wildson Gurgel , Passos Vanara Florêncio 
Published: May 2023

AbstractDental erosion is a chemical process characterized by acid dissolution of dental hard tissue, and its etiology is multifactorial. Dietary polyphenols can be a strategy for dental erosion
management, collaborating to preserve dental tissues through resistance to biodegradation. This study describes a comprehensive review to interpret the effects of polyphenols on dental
erosion of pre-clinical models with in situ designs and simulated acid attacks on enamel and dentin samples. We aim to evaluate evidence about Polyphenolsʼ effects in the type of
dental substrate, parameters of erosive cycling chosen in the in situ models, and the possible mechanisms involved. An evidence-based literature review was conducted using appropriate
search strategies developed for main electronic databases (PubMed, Scopus, Web of Science, LILACS, EMBASE, LIVIVO, CINAHL, and DOSS) and gray literature (Google Scholar). The Joanna Briggs
Institute checklist was used to evaluate the quality of the evidence. From a total of 1900 articles, 8 were selected for evidence synthesis, including 224 specimens treated with polyphenols
and 224 control samples. Considering the studies included in this review, we could observe that polyphenols tend to promote a reduction in erosive and abrasive wear compared to control
groups. However, as the few studies included have a high risk of bias with different methodologies and the estimated effect size is low, this conclusion should not be extrapolated to
clinical reality.
Detecção de Cutibacterium acnes em amostras de tecidos de cirurgias limpas primárias do ombro – Parte II
Authors: Miyazaki Alberto Naoki , Salles Mauro José Costa , Gonçalves Guilherme Vieira , Conte Luiz Henrique Gallego , de Oliveira Thomaz Gê , Santili Ana Beatriz Nappi , Kurihara Mariana Neri Lucas , Santos Ingrid Nayara Marcelino , da Silva Luciana Andrade 
Published: May 2023

Resumo
Objetivo Pesquisa e identificação de Cutibacterium acnes (C. acnes) e de outros microrganismos em amostras de tecidos profundos coletados em cirurgias limpas de ombro em pacientes que não foram submetidos a nenhum procedimento invasivo articular prévio e que não possuíam antecedentes clínicos de infecção.
Métodos Foram analisados os resultados das culturas de amostras de tecidos profundos intraoperatórias de 84 pacientes submetidos à cirurgia limpa primária do ombro. Foram utilizados tubos contendo meio de cultivo para armazenamento e transporte de agentes anaeróbicos, tempo prolongado de incubação e espectrômetro de massa para diagnósticos de agentes bacterianos.
Resultados Foi evidenciado o crescimento de bactérias em 34 pacientes (40,4%) dos 84 incluídos no estudo. Desses, 23 apresentavam crescimento de C. acnes em pelo menos uma amostra de tecido profundo coletada, correspondendo a 27,3% do total de pacientes. O segundo agente mais encontrado foi o Staphylococcus epidermidis, presente em 7,2% do total de indivíduos incluídos. Evidenciamos maior relação da positividade de amostras com o gênero masculino, uma média de idade inferior, a ausência de diabetes mellitus, o escore ASA I e a profilaxia antibiótica na indução anestésica com cefuroxima.
Conclusões Verificou-se um elevado percentual de isolados de diferentes bactérias em amostras de tecidos de ombros de pacientes submetidos a cirurgias limpas e primárias e sem histórico de infecção anterior. A identificação de C. acnes foi elevada (27,6%) e o Staphylococcus epidermidis foi o segundo agente mais frequente (7,2%).
Comparação da perda sanguínea com a utilização do ácido tranexâmico endovenoso e intra-articular versus intra-articular isolado em artroplastia primária de joelho
Authors: Resch Elemar da Silva , Lemos Leandro Silvestro , Santos José Salvador Pantoja dos , Pozzi João Fernando Argento , Konkevicz Ewerton Renato 
Published: May 2023

Resumo
Objetivo O objetivo desse trabalho é comparar a perda sanguínea durante a artroplastia primária de joelho, com a utilização do ácido tranexâmico endovenoso e intra-articular (EV + IA) versus intra-articular (IA) isolado.
Métodos Trata-se de um ensaio clínico randomizado, duplo cego. Pacientes com indicação de artroplastia total primária de joelho foram captados em clínica especializada, onde foram operados pelo mesmo cirurgião, utilizando sempre a mesma técnica cirúrgica. Trinta pacientes foram alocados no grupo ácido tranexâmico EV + IA e 30 pacientes, no grupo IA, conforme randomização. Foi comparada a perda sanguínea através dos níveis de hemoglobina, hematócrito, volume do dreno e estimativa da perda sanguínea (EBL) (cálculo de Gross e Nadler).
Resultados Após a coleta, foram analisados os dados de 40 pacientes, sendo 22 do grupo IA isolado e 18 do grupo EV + IA. Ocorreram 20 perdas por erro de coleta. Entre os grupos IA e EV + IA, não ocorreram diferenças significativas em 24 horas entre os níveis de hemoglobina (10,56 vs. 10,65 g/dL; F1,39 = 0,63, p = 0,429), eritrócito (3,63 vs. 3,73 milhões/mm3; F1,39 = 0,90, p = 0,346), hematócrito (32,14 vs. 32,60%; F1,39 = 1,39; p = 0,240), volume de dreno (197,0 vs. 173,6 mL; F1,39 = 3,38; p = 0,069) e estimativa de perda sanguínea (EBL) (1.002,5 vs. 980,1; F1,39 = 0,09; p = 0,770). O mesmo ocorreu nas comparações realizadas 48 horas pós-operatório. O tempo foi fator significativo para a mudança de todas as variáveis de desfecho. Porém, o tratamento não modificou o efeito do tempo nesses desfechos. Nenhum indivíduo apresentou qualquer evento tromboembólico durante o período do trabalho.
Conclusões O uso do ácido tranexâmico EV + IA não demonstrou vantagem em redução de perda sanguínea quando comparado ao uso de ácido tranexâmico IA isolado nas artroplastias primárias de joelho. Esta técnica demonstrou-se segura, visto que nenhum evento trombo-embólico ocorreu durante o desenvolvimento do trabalho.
A Prospective Study to Evaluate Role of Middle Ear Risk Index in Tympanoplasty with Mastoidectomy as a Prognostic Parameter
Authors: Mathri Archana , Neelamkavi Niya Joseph 
Published: May 2023

Abstract
Introduction Chronic otitis media (COM) is an otological challenge in the developing countries as it is a persistent disease causing severe destruction of middle ear with irreversible sequalae. To assess Middle Ear Risk Index (MERI) score and study its prognostic effect in postoperative outcome following mastoidectomy with tympanoplasty. To evaluate MERI score with respect to graft uptake and A-B gap closure.
Materials and Methods This prospective study comprised 25 patients suffering from COM who presented to the Department of ENT, HSK Hospital, Bagalkot, over a period of 1 year from November 2020 to November 2021. The patients underwent tympanoplasty with mastoidectomy. MERI 2001 was used in the current study, and risk factors were assessed based on pre- and intra-operative findings to obtain the MERI score. Patients were segregated into those with mild (1–3), moderate (4–7), and severe (8–15) MERI. They were evaluated at 1 month follow-up visit.
Results and Conclusion The study reveals the degree to which MERI score can predict the extent of disease and indicate outcome of surgery. In the present study, patients with lower MERI score benefitted more favorably in terms of graft uptake and hearing improvement as compared with success rate of severe MERI score. MERI index is in fact a very reliable predictor of graft uptake and audiological alteration in patients undergoing tympanoplasty with mastoidectomy surgeries for COM.
The Distensibility of Reissner’s Membrane: A Comparative Analysis
Authors: Pender Daniel J 
Published: May 2023

Abstract
Background Distention of Reissner’s membrane in endolymphatic hydrops is a classical otopathologic finding in cases of Meniere’s disease. A recent double hit analysis raised the possibility that the variability in the distensile behavior in Reissner’s membrane may contribute to the vagaries of membrane pathology encountered in this disease. Such distensile variability is suspected to stem from the viscoelastoplastic behavior of the type IV collagen in Reissner’s basement membrane.
Objective To analyze the known distensile characteristics of Reissner’s membrane for evidence of viscoelastoplastic behavior.
Methods Extant data on human Reissner’s membrane were analyzed for distensile characteristics. These features were then compared to the known characteristics of viscoelastoplasticity as manifested by polymers in general as well as a variety of collagenous tissues. These tissues included a synthetic collagen membrane as well as selected mammalian tissues.
Results The limited extant data on human Reissner’s membrane distensile behavior was found to manifest sigmoid load deformation at a lower strain rate of 0.47%/sec and a rigid rupture pattern at a 10-fold higher strain rate of 5.5%/sec. These characteristics were found to be similar to the general characteristics of polymer viscoelasticity, namely a sigmoid load deformation pattern at lower strain rate that stiffens and straightens as strain rate increases. Tensometric data from a synthetic collagen membrane and selected mammalian tissues were found to exhibit comparable load deformation patterns. These findings support the conclusion that human Reissner’s membrane behaves in a viscoelastoplastic manner.
Conclusions Human Reissner’s membrane appears to exhibit viscoelastoplastic behavior comparable to that observed in other collagenous tissues. Such variable distensile behavior provides insight into why the degree of lesion distention before rupture in Meniere’s disease might vary depending on the dynamics of membrane loading and the resultant rate of membrane strain.
Ankle and Foot: Focus on Inflammatory Disease
Authors: Giraudo Chiara , Fichera Giulia , Ganguly Sujata , Arumugam Moorthy , Cecchin Diego , Rennie Winston J. 
Published: May 2023

AbstractThe ankle and foot have numerous bones and complex joints that can be affected by several types of inflammatory arthritis with different patterns and various radiologic signs, depending on the phase of the disease. Involvement of these joints is most frequently seen in peripheral spondyloarthritis and rheumatoid arthritis in adults and juvenile idiopathic arthritis in children. Although radiographs are a mainstay in the diagnostic process, ultrasonography and especially magnetic resonance imaging allow early diagnosis and are crucial diagnostic tools. Some diseases have typical features based on target populations (e.g., adults versus children, men versus women), but others may have overlapping imaging characteristics. We highlight key diagnostic features and describe appropriate investigations to guide clinicians toward the correct diagnosis and provide support during disease monitoring.
Severe Depressive Episode with Psychotic Symptoms: A Homoeopathic Case Study
Authors: Gilla Deepthi , Aswathy B.A. , KR Sreeja 
Published: May 2023

Abstract
Background Global burden of depression has increased in the recent years with reduction in productivity, reduced quality of life, increased morbidity and mortality. Although there is an evidence base for effectiveness of homoeopathy in depression, severe depressive episode (SDE) with psychotic symptoms is challenging for homoeopaths to treat.
Case Summary A 27-year-old female patient presented with dullness, easy fatiguability, withdrawn nature with loathing of life, lack of interest in daily and pleasurable activities. She believed that her body was disfigured and was suspicious that someone was spying on her. The case was diagnosed as SDE with psychotic symptoms (F-32.3 according to International Classification of Diseases, 10th revision). Natrum muriaticum 30 was given as the first prescription and repeated as necessary in the follow-up visits. Carcinosinum 200 was given as intercurrent on the basis of past history of thyroid malignancy. This case presents an example for Hahnemann's concept of Somato-psychic disorder mentioned in §216 of Organon of Medicine.
Results Hamilton Depression Rating Scale score at baseline which was 42 turned to 0 at the end of 6 months and remained the same over a 3 year observation period.
Conclusion Homoeopathic medicines are effective in the management of SDE with psychotic symptoms. Effectiveness of Natrum muriaticum in reducing depressive symptoms and its effect on neurotransmitters is the arena of future research.
Síndrome facetária lombar e a utilização da técnica de ablação por radiofrequência como terapia alternativa: uma revisão sistemática
Authors: Bernardes Anna Luisa Paiva Romano , Correa Renato Ferraz , Trajano Larissa Alexsandra da Silva Neto , Fontes Iberico Alves 
Published: May 2023

ResumoEm um contexto de aumento da prevalência de queixas de dores na coluna, a síndrome facetária se destaca como um importante causador. Alternativas como a ablação por radiofrequência (RF) podem ser uma opção de terapia para alívio da dor crônica que essa patologia pode causar. É necessário analisar a eficácia do tratamento da síndrome facetária pela técnica de ablação por radiofrequência tradicional e o alívio gerado nas dores lombares crônicas (DLC). O presente estudo trata-se de uma revisão sistemática cujo os critérios de inclusão para análise foram: título; estudos observacionais; ensaios clínicos; ensaio clínico controlado; estudos clínicos e publicação nos últimos dezessete anos (2005–2022). Já os critérios de exclusão foram: artigos que abordavam outras temáticas e artigos de revisão. As bases utilizadas para coleta de dados incluíram Medical Literature Analysis and Retrieval System online (Medline), Pubmed, Scientific Electronic Library Online (SciELO), Lilacs, Biblioteca Virtual em Saúde. Os termos utilizados para a pesquisa foram: facet; pain; lumbar; radiofrequency. Aplicando-se os filtros foram encontrados 142 estudos, 12 foram incluídos. Os estudos em sua maioria apontaram ser benéfica a técnica de ablação por radiofrequência tradicional no alívio das dores lombares crônicas refratárias ao tratamento conservador.
Prevalence of Tinnitus and its Characteristics Among Indian Adult Population
Authors: Aryal Sajana , Sharma Yoshita , Prabhu Prashanth 
Published: May 2023

Abstract
Introduction Tinnitus is a sound heard in the ears or head that originates from both external and internal sources. Tinnitus epidemiological data are critical for proper assessment and management of tinnitus sufferers. The study’s goal was to determine the prevalence of tinnitus and its characteristics among middle-aged Indian individuals, as there has been no previous research in this area in India.
Methods A descriptive cross-sectional study was performed in 273 Indian adult populations ranging in age from 18 to 60 years old, utilizing a random sampling approach and an online survey mode. The SPSS 25.0 software was used to conduct the statistical analysis. The descriptive statistics were used to assess the data, and the chi-square test was used to see whether there was any correlation between the variables.
Results Studies related to tinnitus prevalence show larger variability across countries, which may be due to inconsistent research methods used. Our survey found the prevalence of tinnitus to be 6.7% among the Indian adult population, and most of the participants 76 (76%) reported that their tinnitus is of intermittent nature. In our study, we found that 15% of participants have problem with sleep and none of the participants reported perception of tinnitus in their dreams.
Conclusion Tinnitus is the most prevalent otological condition, which may have a great impact on the quality of life of sufferers as well as their family members. As the prevalence of tinnitus is high among adult population, it is very much essential to develop proper assessment and management protocols to help the patient with tinnitus.
Cryogenic sensor enabling broad-band and traceable power measurements
Authors: Girard J.-P. , Lake R. E. , Liu W. , Kokkoniemi R. , Visakorpi E. , Govenius J. , Möttönen M. 
Published: May 2023

Recently, great progress has been made in the field of ultrasensitive microwave detectors, reaching even the threshold for utilization in circuit quantum electrodynamics. However, cryogenic sensors lack the compatibility with broad-band metrologically traceable power absorption measurements at ultralow powers, which restricts their range of applications. Here, we demonstrate such measurements using an ultralow-noise nanobolometer, which we extend by an additional direct-current (dc) heater input. The tracing of the absorbed power relies on comparing the response of the bolometer between radio frequency and dc-heating powers traced to the Josephson voltage and quantum Hall resistance. To illustrate this technique, we demonstrate two different methods of dc-substitution to calibrate the power that is delivered to the base temperature stage of a dilution refrigerator using our in situ power sensor. As an example, we demonstrate the ability to accurately measure the attenuation of a coaxial input line between the frequencies of 50 MHz and 7 GHz with an uncertainty down to 0.1 dB at a typical input power of −114 dBm.
CASPT2 study of the electronic structure and photochemistry of protonated N-nitrosodimethylamine (NDMA-H+) at 453 nm
Authors: Soto Juan , Peláez Daniel , Algarra Manuel 
Published: May 2023

In this work, we have studied the photodissociation of the protonated derivatives of N-nitrosodimethylamine [(CH3)2N–NO] with the CASPT2 method. It is found that only one of the four possible protonated species of the dialkylnitrosamine compound absorbs in the visible region at 453 nm, that is, N-nitrosoammonium ion [(CH3)2NH-NO]+. This species is also the only one whose first singlet excited state is dissociative to directly yield the aminium radical cation [(CH3)2NHN·]+ and nitric oxide. In addition, we have studied the intramolecular proton migration reaction {[(CH3)2N–NOH]+ → [(CH3)2NH–NO]+} both in the ground and excited state (ESIPT/GSIPT); our results indicate that this process is not accessible neither in the ground nor in the first excited state. Furthermore, as a first approximation, MP2/HF calculations on the nitrosamine–acid complex indicate that in acidic solutions of aprotic solvents, only [(CH3)2NH–NO]+ is formed.
Effects of language familiarity, utterance length, and speech quality
in prosodic boundary identification
Authors: Kuo Chen-Hsiu Grace 
Published: May 2023

Abstract
This study investigates the effects of several stimulus sources:
language familiarity, utterance length, and speech quality, on listeners’
predictions of the sizes of the upcoming prosodic boundaries. Experiments with
native Taiwanese speakers were conducted, and the stimuli varied in prosodic
boundary units (i.e., word, phrase, and sentence), languages (i.e., Taiwanese,
English, and Swedish), utterance lengths (i.e., 2-second, and 2 syllables; the
latter is approximately 0.416-second long), and speech qualities (i.e., normal
speech, low-pass filtered speech). Results showed that: (a) listeners performed
better when the utterances were longer; (b) listeners performed better in
low-pass filtered speech when they had no prior knowledge of the target
language; (c) there was a tendency for the language familiarity effect, but this
effect was heavily influenced by the extent of similarity of the phonetic
realizations in different prosodic boundaries, and the listeners’ language
proficiency which was associated with working memory storage capacity.
再談漢語「是」字句及幾類相關結構的語義
Authors: Liu Ying , Cheng Gong 
Published: May 2023

抽象的本文通過兩項實證性的研究，再談漢語分裂式「是」句及幾類相關結構的語義。研究發現(i)不同於Paul & Whitman (2008)、Cheng (2008)等分析，句首、句中「是」字句以及「是」字句和「是……的」結構在焦點標記方式和窮盡性的表達等分裂句相關語義屬性上具有一致性，因此應該進行統一化的處理。(ii)分裂式「是」字句的核心語義表達唯一性識別，其預設焦點候選項集合中有且只有一個唯一為真的候選項並斷言其自身表達的命題(prejacent)為真。「是」字句的窮盡性來自於預設和斷言共同作用下的語義推理，而對比性則來自於語篇在此基礎上的進一步限制作用。(iii)「是」字句同幾類相關結構（如斷言命題句，真值焦點句等等）具有共同的語義內核，即表達唯一性識別，而其區別則主要來自於各類句型中焦點成分屬性的不同。這樣的分析不但有助於更精確的語言事實描寫，也可以幫助我們更加系統化的理解漢語分裂句系統。
上聲來源(< -ʔ)新證
Authors: Mei Tsu-Lin 
Published: May 2023

抽象的本文說明(1)「尾、𤈦、苦、雨、九、子、犬、乳、屎、邇」這10個上聲字在藏緬語(Chepang, Lushai)的同源詞帶著-ʔ。由此可見上古漢語的上聲來自漢藏語的*-ʔ。(2)上古漢語的「虎」字*khlaʔ以及古緬語的klaʔ（老虎）都是借自孟高棉語(Mon-Khmer)*klaʔ（老虎）。*klaʔ的-ʔ就是漢語「虎」字上聲的來源。
Fabrication of low-cost MEMS microfluidic devices using metal embossing technique on glass for lab-on-chip applications
Authors: Madhankumar P , Sujatha L , Sundar R , Viswanadam Gautham 
Published: May 2023

Abstract
This paper discusses a low-cost technology for the fabrication of microfluidic devices on glass substrate using metal embossing technique. The fabrication technique demonstrated is a much simpler approach of embossing on glass using thermo-compression process with a patterned metal layer to define device structure. Well established printed circuit board fabrication photo-process is used to realize the desired planar geometry on metal layer deposited over a glass substrate. The depth of the channel is defined by the thickness of the metal deposited by electro-plating. The embossing technology offers a relatively safer approach conducive to batch processing to enable repeatable, high-yield, low-cost devices fabricated using low-cost equipment. Major challenges of achieving adhesion of the deposited thick nickel layer without peel-off and control of the thermo-compression process to achieve reliable and repeatable embossing without structural distortions were addressed. To prove its suitability for manufacturing, experiments were carried out with full wafer of 6″ × 6″ square glass wafer and optimal process steps for low-cost microfluidic device manufacturing have been well established.
Design and analysis of a metasurface-based wideband wide-angle scanning phased array
Authors: Qi Huanhuan , Liu Haiwen 
Published: May 2023

Abstract
This paper presents a wideband wide-angle scanning phased array, which employs Φ-shaped unit cells to form a metasurface (MS) for achieving wideband impedance matching. To optimize the impedance matching performance, a design procedure based on an equivalent circuit model is proposed. A quasi-analytical model based on the equivalent circuit model and the permittivity ϵ
r and permeability μ
r of the MS properly predicts the scan range of the full structure, and allows for an accelerated design process. The extensive analysis confirms the effectiveness of the MS as the wideband angle impedance matching layer for the antenna array. The MS has demonstrated a positive impact on the wideband wide-angle scanning performance. Finally, a prototype is fabricated and measured, and the experimental results agree well with the simulation results. The proposed array exhibits wide-angle scanning across a 3.5:1 impedance bandwidth (2–7 GHz) with ±60° scan volume in both E-plane and H-plane.
Reproduced out-of-plane ferroelectricity in monolayer SnTe van der Waals heterostructures
Authors: Song Wenjing , Cao Wang , Zhao Wei , Ding Jianwen 
Published: May 2023

Abstract
Due to the shrinking in size of nonvolatile memory devices, the two-dimensional ferroelectric van der Waals (vdW) heterostructures have received huge attention. However, it is still difficult to maintain the out-of-plane (OOP) ferroelectricity. In this work, we have theoretically investigated the relationship between the ferroelectricity and the strain of bulk and few-layer SnTe by first-principles calculations. The results indicate that the α-SnTe can exist stably within the strain between −6% and 6%, and the complete OOP polarization occurs within the strain between −4% and −2%. Unfortunately, the OOP polarization disappears while the bulk α-SnTe is thinned to a few layers. However, the complete OOP polarization recurs in monolayer SnTe/PbSe vdW heterostructures, which is due to the strong interface coupling. Our findings provide an effective way to enhance ferroelectric performance, which is beneficial for the design of ultra-thin ferroelectric devices.