bluuebunny/crossref_metadata_2025_split huggingface dataset:
Case Report: Anesthesia management of a patient that requires lung isolation with tracheal stenosis and an anterior airway
Authors: Raviv Abrar , Kessaris Christos P. 
Published: August 2023

Abstract
Background: Under general anesthesia, double lumen endotracheal tubes are frequently used in the surgical management of cases requiring lung isolation. However, a single lumen endotracheal tube with a bronchial blocker might be necessary in instances of tracheal stenosis or difficult airways.
Case Presentation: We describe a case of a 67-year-old female with a large lung cyst who showed signs of both tracheal stenosis and an anterior airway who underwent cyst removal. Under GlideScope videolaryngoscopy, a transition from a double lumen endotracheal tube to a single lumen endotracheal tube in conjunction with a bronchial blocker was required, which allowed for successful cyst removal from the patient with effective selective lung ventilation with uneventful recovery.
Conclusion: It is an original case report, which demonstrates the transition from a double lumen tube to a single lumen tube in conjunction with a bronchial blocker in the incident of both tracheal stenosis and an anterior airway under the guidance of the GlideScope.
Prevalence, determinants, intervention strategies and current gaps in addressing childhood malnutrition in Vietnam: a systematic review
Authors: Mondon Charlotte , Tan Pui Yee , Chan Chong Ling , Nga Thuy Tran , Gong Yun Yun 
Published: August 2023

Abstract
Background
Childhood malnutrition in all forms is a major public health issue worldwide. This review aimed to systematically examine the prevalence and determinants, and identify the potential interventions and current gap in addressing malnutrition including undernutrition, overnutrition and micronutrient deficiencies (MNDs) in Vietnamese children aged 0–18 years old.
Methods
Embase, Scopus, PubMed, and Web of Science were systematically searched through June 2022 to identify relevant articles published within the past 25 years. Study selection and data extraction were performed by one reviewer and checked for accuracy by the other two reviewers in accordance with PRISMA guideline. Risk of publication bias was assessed using American Dietetic Association Quality Criteria Checklist.
Results
81 studies that met the inclusion criteria were included. Undernutrition have been decreased over time but still 22.4%, 5.2% and 12.2% of children under 5 were stunted, wasted and underweight, respectively. Prevalence of MNDs varied by age, regions or socio-economic groups, with 11.4–89.9%, 11–90%, 23–87%, 11–58% and 8–20% of Vietnamese children were anaemic and iron, zinc, vitamin D and retinol deficient, respectively. Overweight and obesity is now on the rise (7.4–22%). The key determinants of undernutrition/MNDs included living in rural areas, children with low birth weight, and poor socio-economic status, whereas living in urban and affluent areas, having an inactive lifestyle and being a boy were associated with increased risk of overweight or obesity. Nutrition specific intervention studies including supplementation and food fortification consistently showed improvements in anthropometric indices and micronutrient biomarkers, and national nutrition sensitive programmes also provided nutritional benefits on child’s growth and eating behaviours, but lack of data on childhood overweight.
Conclusion
Stunting is still prevalent at 20% in Vietnamese children (< 5years) despite a significant reduction over the decade. MNDs remain to be a serious problem, whilst overweight and obesity are rapidly rising requiring attention and intervention. This finding highlights the needs for double duty actions to simultaneously and effectively address different forms of childhood malnutrition in Vietnam. However, evidence on the potential intervention strategies, especially on MNDs and overnutrition are still limited to inform policy decision, thus future researches are warranted.
Transversotrema patialense var. hafniensis infection in Poecilia reticulata by cercariae released from Melanoides tuberculata in Denmark: Implications for fish health and bioinvasion
Authors: Buchmann Kurt , Kania Per Walter 
Published: August 2023

Abstract
Background
Exotic and ornamental fish are highly popular companion animals in industrialized human societies resulting in a significant transcontinental trade of fish, invertebrates or aquatic plants. A major issue is the diseases associated with these organisms as they have a major impact on health of the fish in both public and private household aquaria. A secondary issue is the trade with these products, which potentially may expand the distribution area and spread a range of diseases to new habitats.
Results
We here describe how Poecilia reticulata Peters, 1859 (guppy), produced in a private household aquarium, were invaded by cercariae of an exotic trematode released by imported snails. The fish presented with severe clinical signs (tremor, flashing, scraping of body against objects). A standard parasitological examination and morphometric identification showed the disease to be caused by scale pocket infections with a species within the genus Transversotrema patialense (Soparkar, 1924), an exotic digenean trematode. Molecular identification by PCR, sequencing and BLAST analysis indicated that the parasite was an undescribed variant and the isolate was therefore named T. patialense var. hafniensis.
Conclusions
GenBank sequences for species within the genus Transversotrema are sparse and fragmented and we here present the entire 2646 bp sequence of encoding ribosomal RNA (partial 18S, ITS1, 5.8 S, ITS2, partial 28S) and a 1107 bp sequence of mitochondrial DNA (CO1). These are recommended for future diagnostics use and separation of sister species within T. patialense sensu lato. The fish were not purchased from a pet shop but produced in the home aquarium. This indicated that an infection pressure existed in the aquarium, where the source of infection was found to be exotic intermediate host snails Melanoides tuberculata (Müller, 1774), which originally were imported and purchased from a pet shop. They were recovered from the facility and shown to release infective cercariae, which infected naïve guppies. We frame that trade with infected snails may not only challenge the health of fish in aquaria but also represent a risk for spread of exotic fish diseases to new geographic regions where climate changes may facilitate their establishment.
Array-Based Statistical Analysis of the MK-3 Customizable Authenticated Encryption Algorithm
Authors: Bajorski Peter , Kaminsky Alan , Kurdziel Michael , Łukowiak Marcin , Radziszowski Stanisław 
Published: August 2023

Abstract
To provide security autonomy capability, such that different users can have independent variants of the encryption algorithm, MK-3 is designed to be customizable. Two levels of customization are supported, Factory Customization and Field Customization. Customization is done by modifying functions and function parameters in the algorithm to yield unique cipher functions while preserving the algorithm’s cryptographic security.
The main goal of this work is to present the results from the statistical analysis of the customizable MK-3 encryption cypher, focusing on field customized mixers. We recall the main components of the MK-3 algorithm and overview a subset of available factory and field customizations for MK-3. We test the main instances of the field customized versions and give a general argument for their desired statistical properties expected from an encryption cypher.
Driving Magnetosphere Convection through the ionosphere
Authors: Dai Lei , Zhu Minghui , Ren Yong , Wang Chi , Gonzales Walter , Samsonov Andrey , Escoubet Philippe , Tang Binbin , Zhang Jiaojiao , Branduardi-Raymont Graziella 
Published: August 2023

Abstract
The Dungey cycle is a fundamental concept in understanding magnetosphere convection in the presence of the interplanetary magnetic field (IMF). It explains that the convection within the closed part of the magnetosphere is primarily driven by magnetic reconnection in the nightside magnetospheric tail. Here we provide evidence that magnetospheric convection can also be driven solely by dayside magnetic reconnection, specifically through the ionosphere's two-cell convection. The enhanced convection progresses from the dayside to the nightside and responds rapidly, within 10-20 minutes, to a southward turning of the IMF. Uncovering this physical process provides new insights into the driving mechanisms behind planetary magnetosphere convection.
A qualitative study of the symptom management in patients with chemotherapy-induced hand-foot syndrome
Authors: Zhang Jie , Wang Chen , He Qian-Yun , Mao Dong-Liang , Huang Lei , Wang Mei , Zhang Jun 
Published: August 2023

Abstract
Purpose
To investigate the ability to self-manage symptoms in patients with chemotherapy-induced HFS and to provide guidance for developing a self-management plan that meets patient needs.
methods
From July 2022 to July 2023, 22 patients with chemotherapy-induced HFS were selected by objective sampling in the oncology department of a tertiary hospital in Shanghai. A semi-structured in-depth face-to-face interview was used to collect the case data, and the content analysis method was used for analysis, and the topic was refined.
Results
Twenty-two patients were interviewed. Three themes and six sub-themes emerged from the analytical interviews: the first theme was "Patient attitude and emotional response to symptoms," which consisted of patients gradually accepting the symptoms of HFS and adapting to some mild manifestations based on the following responses, showing different emotional responses to HFS, symptoms that affected their daily life. The patient feels guilty for his family and suffers from a self-image disorder. The second theme is "symptom experience," with symptoms that vary from patient to patient and have a different impact on the individual's life, including pain and itching. The third theme is "coping strategies," which include patients feeling the effects of limited social interaction and family relationships. The fourth topic, "Expectations for the future," includes gaining relevant knowledge through the website, doctors, and patients, changing habits, demonstrating symptom improvement, and meeting/exceeding the expectations of healthcare providers.
Conclusions
Healthcare providers should provide more education and emotional support to patients with chemotherapy-induced HFS to enable symptom management, elicit positive experiences.
Study Of Epilithic Cyanobacteria On The Walls Of Garh Palace And Abheda Mahal Of Kota, Rajasthan
Authors: Sharma Pooja , Shrivastava Neerja , Scholar Research 
Published: August 2023

Abstract
Cyanobacteria also called Blue Green Algae are gram negative, oxygenic photosynthetic prokaryotes. They show the ability of efficient nutrient uptake mechanism. Ancient monuments and temples are more exposed to sunlight and moisture of the environment and are the easiest sites for microbial colonization. Microbes are able to colonize on the walls of historical monument by forming biofilms or patinas. Biofilms of microbial cells degrade the asthetic value of ancient buildings and require lots of time and investment to eliminate them. The primary colonizers of stone monuments are seen as photosynthetic microorganisms (algae and Cyanobacteria). Many of the species of Cyanobacteria are able to tolerate climate extremes and hence require more attention to be study. It has been seen that Cyanobacteria need only light and water to grow and therefore can grow endolithically (4). They can tolerate extreme climate conditions. Cyanobacteria are able to survive on exposed surfaces of ancient walls and are greatly involved in biodeterioration of monuments (2). This makes more concern about the study of Cyanobacteria as they the agents of stone property degradation in future. Kota city is situated near the bank of river Chambal. Kota have semi-arid climate throughout the year. Garh Palace also known as City palace is a historic place since foundation laid in 1264 C.E by Prince Jait Singh of Bundi. It comprises number of architectural structures of ancient times. It has a huge museum which displays royal arms and ammunitions. Another ancient monument is Abheda Mahal situated near Chambal River, built by Ummed Maharaj. It is also rich in heritage with beautiful pond inside it. Total 12 species isolated from the walls of monuments generally belongs to genus Nostoc (1), of the genera Gloeocapsa (2), Gloeothece (2), Aphanothece (1), Chroocococcus (2), Chroococcidiopsis (1), Tolypothrix (1) and Aulosira (1) of Cyanophyta.
Identification of sialoylation-related genes as a new diagnostic biomarker of atherosclerosis by machine learning
Authors: Song Wei , Xue Jian-feng , Liu Ji-fang , Feng Yue , Yao Na , Yin Lu-hua , Yang Hong-Peng , Sun Hai-peng , Zhang Pu 
Published: August 2023

Abstract
Background:
Atherosclerosis (AS) is a pathological change based on the disorder of lipid metabolism, which is related to the inflammatory process of vascular wall and the high level of low-density lipoprotein. Sialoylation is a post-translational modification controlled by sialyltransferase, transporter and neuraminidase family. This process plays a key role in a variety of biological functions. Abnormal sialylation is related to a variety of diseases, including cancer, pathogen infection and cardiovascular disease (CVD). Therefore, this study aims to explore the role of sialylation related genes in AS.
Methods:
Two AS data sets were obtained from the gene expression comprehensive database (GEO). Based on the differentially expressed genes (DEGs) and the sialylation gene set, the differentially expressed sialylation-related genes (De-SRGs) were found. Then, machine learning method is used to find the core gene. The immune cell infiltration method was established to study the immune cell imbalance in AS. Subsequently, we explored two different subtypes based on core genes using 158 AS samples. Gene ontology (GO), Kyoto Encyclopedia of Genes and Genome (KEGG) pathway enrichment, gene set variation analysis (GSVA) and immunoinfiltration analysis are also used to evaluate the different roles of subtypes.
Results:
A total of 36 De-SRGs were identified. Through machine learning algorithm, 5 core genes were identified and 2 subtypes related to core genes were defined. The results of GSVA showed that type A inflammatory response related pathways were significantly enriched, while type B inflammatory response related pathways were significantly enriched.
Conclusion:
Through this study, we have revealed the relationship between Sialylation-related genes and AS, as well as the heterogeneity of AS patients with different Sialylation subtypes. Selecting a Sialylation-signature based on five genes as the best machine learning model can accurately evaluate the diagnosis of AS and control patients. Our research results reveal the progress of Sialylation in AS for the first time, and provide new insights for its potential pathogenesis and potential treatment strategies.
Association of postoperative adverse events with low skeletal muscle mass measured from the 12th thoracic vertebral skeletal muscle mass in oral cancer patients
Authors: Fujii Arisa , Suzuki Taiki , Sakai Katsuhiko , Matsuura Nobuyuki , Sugahara Keisuke , Katakura Akira , Nomura Takeshi 
Published: August 2023

Abstract
Background
Sarcopenia is characterized by a progressive and generalized loss of skeletal muscle mass and strength. The aim of this study was to investigate the impact of skeletal muscle mass on adverse events in free-flap reconstruction for defects after oral cancer resection.
Methods
The participants were a non-randomized retrospective cohort of 120 patients who underwent this procedure after preoperative diagnostic computed tomography. Cross-sectional areas (cm2) of skeletal muscles in the Th12 region were measured by manual outlining of computed tomography images. Subsequently, the skeletal muscle Cross-sectional areas at level L3 was estimated using the prediction rule described by Matsuyama et al. These areas were then normalized to height (cm2/m2) and defined as the skeletal muscle index.
Results
Recipient-site adverse events occurred in 56 patients (46.7%), and recipient-site surgical site infections occurred in 45 patients (37.5%). Skeletal muscle index was significantly associated with recipient site adverse events in univariate analysis (P < 0.05). Lower body mass index and skeletal muscle index were significantly associated with recipient site surgical site infection in univariate analysis (P < 0.05). In the multiple logistic regression model, a lower skeletal muscle index was a significant risk factor for recipient site adverse events and surgical site infections (adverse events odds ratio; 3.17/P = 0.04; surgical site infection odds ratio; 3.76/P = 0.02).
Conclusions
These results suggest that low skeletal muscle index in Th12 is particularly associated with adverse events and that it is a predictor of surgical site infections.
Random Informative Advertising with Vertically Differentiated Products
Authors: Lahmandi-Ayed Rim , Laussel Didier 
Published: August 2023

Abstract
We study a simple model in which two vertically differentiated firms compete in prices and mass advertising on an initially uninformed market. Consumers differ in their preference for quality. There is an upper bound on prices since consumers cannot spend more on the good than a fixed amount (say their income). Depending on this income and on the ratio between advertising cost and quality differential (relative advertising cost), either there is no equilibrium in pure strategies or there exists one of the following three types: 1) an Interior equilibrium where both firms have positive natural markets and charge prices lower than the consumer’s income; 2) a Constrained interior equilibrium where both firms have positive natural markets and the high-quality firm charges the consumer’s income or 3) a Corner equilibrium where the low-quality firm has no natural market selling only to uninformed customers. We show that no corner equilibrium exists in which the highquality firm would have a null natural market. At an equilibrium (whenever there exists one), the high-quality firm always advertises more, charges a higher price and makes a higher profit than the low-quality one. As the relative advertising cost goes to infinity, prices become equal and the advertising intensities converge to zero as well as the profits. Finally, the advertising intensities are, at least globally, increasing with the quality differential.
JEL classification: D83, L13, M37.
Expression of preference for the disclosure of secondary findings of comprehensive genomic profiling tests by cancer patients and relatives
Authors: Kimbara Shiro , Toyoda Masanori , Kiyota Naomi , Hanafusa Hiroaki , Niwa Yui , Tanaka Keiko , Uchida Megumi , Wada Yui , Komatsu Masato , Imamura Yoshinori , Funakoshi Yohei , Minami Hironobu 
Published: August 2023

Abstract
Background
Secondary findings (SFs) in comprehensive genomic profiling (CGP) testing can affect not only the healthcare of cancer patients but also their first-degree relatives. To date, however, the preferences of first-degree relatives concerning the disclosure of SFs have been not elucidated compared to that of cancer patients.
Methods
We retrospectively investigated the preferences of adult patients who underwent CGP tests and their adult first-degree relatives. Main outcomes were (i) the proportion of patients and first-degree relatives who expressed their preference before the results of CGP tests were disclosed; and (ii) the proportion of patients and first-degree relatives who opted for disclosure of SFs.
Results
Seventy-three patients and 252 first-degree relatives were included. All patients had expressed their preference, and all patients except one opted for disclosure. In contrast, only 41% of the 252 first-degree relatives expressed a preference prior to disclosure: 34% opted for disclosure and 7% refused disclosure. On multivariate analysis, the failure of first-degree relatives to express a preference was associated with old age and absence from pre-test explanatory sessions at the cancer genome clinic. All patients received a pre-test explanation from health professionals; in contrast, only 8% of first-degree relatives received an explanation from health professionals, while a further 35% of first-degree relatives received an explanation from the patient and 36% receive no pre-test explanation of SFs at all.
Conclusion
Our study highlights the difficulty of respecting the autonomy of individual first-degree relatives, particularly for those who do not attend pre-test explanatory sessions or are elderly.
Modified neoadjuvant rectal score as a novel prognostic model for rectal cancer patients who underwent chemoradiotherapy
Authors: Kawai Kazushige , Ozaki Kosuke , Nakano Daisuke , Dejima Akira , Ise Ichiro , Nakamori Sakiko , Kato Hiroki , Natsume Soichiro , Takao Misato , Yamaguchi Tatsuro , Ishihara Soichiro 
Published: August 2023

Abstract
Background: The neoadjuvant rectal score (NAR score) has recently been proposed as a better prognostic model than the conventional TNM classification for rectal cancer patients that have undergone neoadjuvant chemoradiotherapy. We recently developed an apoptosis-detection technique for assessing the viability of residual tumors in resected specimens after chemoradiotherapy. This study aimed to establish an improved prognostic classification by combining the NAR score and the assessment of the apoptosis of residual cancer cells.
Methods: We retrospectively enrolled 319 rectal cancer patients who underwent chemoradiotherapy followed by radical surgery. The recurrence-free survival and overall survival of the four models were compared: TNM stage, NAR score, modified TNM stage by re-staging according to cancer cell viability and modified NAR score also by re-staging.
Results: Down-staging of the ypT stage was observed in 15.5% of cases, whereas only 4.5% showed down-staging of ypN stage. C-index was highest for the modified NAR score (0.715), followed by the modified TNM, TNM, and NAR score. Similarly, Akaike’s information criterion was smallest in the modified NAR score (926.2), followed by modified TNM, TNM, and NAR score, suggesting that the modified NAR score was the best among these four models. The overall survival results were similar: c-index was the highest (0.767) and Akaike’s information criterion was the smallest (383.9) for the modified NAR score among the four models tested.
Conclusions: We established a novel prognostic model, for rectal cancer patients that have undergone neoadjuvant chemoradiotherapy, using a combination of apoptosis-detecting immunohistochemistry and neoadjuvant rectal scores.