bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALISIS FAKTOR – FAKTOR YANG MEMPENGARUHI KEBERLANJUTAN USAHATANI RUMPUT LAUT DI DESA KALIUDA KABUPATEN SUMBA TIMUR
Authors: Retang Elfis Umbu Katongu 
Published: January 2023

penelitian ini bertujuan untuk mengetahui factor – factor yang mempengaruhi keberlanjutan usahatani rumput laut di Desa Kaliuda, Kecamatan Pahunga Lodu, Kabupaten Sumba Timur. lokasi ditentukan secara purposive dengan mempertimbangkan bahwa Desa Kaliuda adalah pusat budidaya rumput laut di Kabupaten Sumba Timur. Penelitian ini merupakan penelitian deskriptif kuantitatif dengan menggunakan 92 orang sampel sebagai responden penelitian. analisis data dalam penelitian ini adalah menggunakan metode deskriptif dan analisis Smart Partial Least Square (PLS) version 2.0 yang digunakan dalam melihat pengaruh faktor teknis, sosial dan ekonomi terhadap keberlanjutan usahatani budidaya rumput laut. hasil dari penelitian ini menunjukan bahwa di Desa Kaliuda, Kecamatan Pahunga Lodu, Kabupaten Sumba Timur keberlanjutan usahatani budidaya rumputlaut dipengaruhi secara positif dan signifikan oleh faktor teknis, sosial dan ekonomi.

Kata Kunci: Rumput laut, keberlanjutan, Desa Kaliuda
MODERN METHODS OF NON-INFLAMMATORY CHRONIC PELVIC PAIN SYNDROME TREATMENT
Authors: Zasieda Yurii 
Published: January 2023

Relevance. Today there is an additional progressive option to apply into the non-inflammatory CPPS, which is presented by regenerative medicine and specifically platelet-rich plasma(PRP) treatment.
Aim – to evaluate efficacy of PRP treatment in combination with pharmacotherapy and ESWT for non-inflammatory CPPS.
Materials and methods. Prospective study was conducted in a group of 40 outpatients with diagnosis of non-inflammatory chronic pelvic pain syndrome in Men’s Health Clinic (Kyiv, Ukraine). Mean age was equal to 46.4±10.2. The set of specific examinations included: trans-rectal prostate scanning, prostate secret sample analysis, visual analogue pain scale (VAS), International Prostate Symptom Score (IPSS) and International Index of Erectile Function (IIEF-5).
Results. Study results showed that there are significant differences in mean VAS scores in time point at 28-th day of treatment where patients of MG demonstrated lower pain level (p<0.05) than patients of CG, meanwhile both groups had significant (p<0.05) decrease of pain levels in comparison with initial data. In 3 months after treatment, we could see elevation of pain in CG to the level that have no significant differences with initial data, while patients of MG still have significantly lower pain level, but difference between groups come insignificant.
IPSS levels at 28-th day of treatment showed significant (p<0.05) efficacy (bringing symptoms from moderate to mild level) in both groups with lack of difference between them. Such situation was observer also in 3 months after treatment with slight increase of symptom intensity in both MG and CG. In 6 months after treatment, we have registered elevation of IPSS mean score in CG up to the level of insignificant difference with initial data.
IIEF-5 data showed significant (p<0.05) improvement of symptoms at 28-th day of treatment in both CG and MG without significant difference between groups. In 3 months after treatment, we observed that in CG the level of symptoms raised to the level that have insignificant difference with initial data, but in MG the improvement was still significant. The same situation was observed in 6 months after treatment.
Conclusions. The efficacy of PRP treatment in combination with pharmacotherapy and ESWT for non-inflammatory CPPS was evaluated. Significant clinical effects were found both for PRP combination with ESWT and NSAID and just ESWT and NSAID directly after course of treatment, meanwhile in 3 and 6 months after treatment the results start to show difference in favor of PRP inclusion.
STRUCTURED PSYCHODIAGNOSTIC INTERVIEW IN PATIENTS WITH BODILY DYSPHORIA (IN CONTEXT OF INTERNET COMMUNICATION)
Authors: Gorodokin Anton , Dyoma Inna , Stolyarenko Andrii 
Published: January 2023

Relevance. Psychological study of the phenomenon of “bodily dysphoria” as a distress caused by abnormal-negative perception of one’s own body. Elaboration of the concept of “bodilydysphoria” requires the establishment of biographical, family, traumatic, social, introspective and behavioral characteristics of a distress.
Aim. To develop the structure of clinical psychodiagnostic’s interview for body-associated distress systematization in patients with gender dysphoria, body dysmorphic disorder and eating disorders.
Materials and methods. Perspective study took place in period of 2018-2021 on the contingent of 116 patients with main diagnosis of GD (36 patients), BDD (38 patients) and ED (42 patients) who were enrolled into the study as volunteers both and underwent semi-structured personal (31 cases) or online-interview (85 cases).
Results. In our approach we used 3 basic affective reactions: frustration (described as a heavy feeling of the need to change the existing circumstances when it is impossible, which is associated with despair, a sense of hopelessness), anxiety (described as an expectation of negative consequences) and adversion (described as disgust, emotional rejection of existing circumstances).
Conclusions. The structured psychodiagnostic interview for distress pattern recognition was developed basing on the psychological study of 116 patients with gender dysphoria, eating disorders and body dysmorphic disorder.
Study population was examined by clinical psychologist and underwent testing for internet addiction that showed levels of addictive pattern of internet use: 66.7% in GD patients; 71.4% in BDD patients; 63.1% in ED patients.
Created the structure of 13 distinct distress categories that analysed by 146 questions, which are aimed to recognize possible personal reactions to correspondent “triggers”. Possible emotional reactions were classified to 3 negative categories – adversion, frustration and anxiety; 1 neutral category and 1 positive category – pleasure. General analysis of distress patterns showed that GD could be characterized as equally presented by all 3 negative categories (adversion, frustration and anxiety); ED presented by anxiety and frustration, BDD presented mostly by adversion and frustration.
ПРОТЕОЛІЗ В ПАТОГЕНЕЗІ АЛЕРГІЧНИХ ЗАХВОРЮВАНЬ
Authors: Kravets Tetiana , Harieiev Oleksii , Lobanova Kateryna 
Published: January 2023

Мета виконаної роботи полягала у прагненні експериментально підтвердити уявлення про запальну природу алергічних реакцій, де флогогеном виступають пептиди зовнішнього середовища зі збереженими епітопними послідовностями внаслідок неповноцінного гідролізу до амінокислот. Виникаючий ефект пов’язаний із вродженою або набутою вибірковою ферментопатією зовнішніх протеолітичних ферментів мікробіома.
Матеріали та методи. В експеримент були взяті 22 штами мікроорганізмів, що становлять транзиторну і нормофлору кишківника людини, що формують групу пробіотичних мікроорганізмів, і широко використовуються як біологічно активні добавки (БАД) різними прописами як засіб терапії. Оцінювалася каталітична дія зовнішніх протеолітичних ферментів досліджуваних мікроорганізмів у реакціях гідролізу білків макронутрієнтів in vitro. Культивування мікроорганізмів проводилося на селективних живильних середовищах із доданими до них екстрактами білків коров’ячого молока, курячого яйця, сої, пшениці, арахісу. Продукти гідролізу фіксувалися з використанням електрофорезу в поліакріламідному гелі. Як контроль враховувався результат електрофорезу компонентів екстрактів досліджуваних білків.
Результати та їх обговорення. Зазначається у досить великому числі випадків каталітична активність ферментів мікроорганізмів з різних таксономічних груп в реакціїгідролізу одного конкретного білка, що дає підставу розцінювати це явище як фактор різноманітності, що забезпечує стійкість такої екосистеми як мікробіом людини.Так само важливо взяти до уваги, що ферментна активність близькоспоріднених мікроорганізмів у гідролізі білків не носить однотипний характер, що робить можливимотримати продукти гідролізу як джерело метаболізму мікробів з багатьох різноманітних білків. Таке явище може мати пристосувальний характер харчового синергізму.
Висновки. Є підстави розцінювати прояви алергії як один із варіантів запальної реакції, тобто синдром, сукупність симптомів запалення, що супроводжують соматичне абофункціональне захворювання, в патогенезі якого присутня ензимопатія щодо окремих протеолітичних ферментів.
ХАРАКТЕРИСТИКА ТИПУ СТАВЛЕННЯ ДО ХВОРОБИ У ХВОРИХ НА ШИЗОТИПОВИЙ РОЗЛАД З АФЕКТИВНОЮ ПАТОЛОГІЄЮ РІЗНОГО СПЕКТРУ
Authors: Плєхов Владислав Андрійович 
Published: January 2023

З метою виявити особливості типу відношення до захворювання хворих на шизотиповий розлад залежно від спектру наявної афективної патології шляхом аналізу її клініко-психопатологічного наповнення, було проведено проспективне дослідження.
Матеріали та методи. Протягом 2019-2020 рр. було досліджено 100 пацієнтів Запорізької регіональної психіатричної лікарні, що знаходились на амбулаторному етапі лікування з приводу шизотипового розладу; для вирішення поставленої мети були використані клініко-анамнестичний, клініко-психопатологічний, психодіагностичний та клініко-статистичний методи. Контингент дослідження було розподілено на три групи: до групи дослідження 1 (Г1) увійшли 52 хворих, у яких була виявлена уніполярна психопатологічна симптоматика депресивного спектру; до групи дослідження 2 (Г2) увійшли 16 хворих, що демонстрували циклічну зміну депресивних та гіпоманіакальних фаз; останні 32 хворих сформували групу дослідження 3 (Г3) – вони виявляли клінічні ознаки афективного сплощення.
За результатами дослідження було встановлено, що для хворих Г1 були більш характерні іпохондричні варіанти реагування на захворювання: значного поши- рення тут набули ізольований іпохондричний (7 хворих) та комбінований тривожно-іпохондричний (10 хворих) типи відношення до захворювання. Для хворих Г2 специфічними були ізольований анозогнозичний (5 хворих) та комбінований ейфорійно-анозогнозичний варіанти відношення до захворювання (2 хворих). Специ- фічним варіантом відношення до захворювання для хворих Г3 був анозогнозичний (18 хворих).
Висновок. Для хворих на шизотиповий розлад із превалюванням уніполярної депресивної симптоматики характерні тривожно-іпохондричні варіанти реагування на захворювання, для хворих із циркулярною зміною афективних фаз ейфорійно-анозогнозичний варіант, для хворих зі станами афективного сплощення – анозогнозичний.
EFFECT FRAUD DIAMOND THEORY DETECTING FINANCIAL STATEMENT FRAUD WITH PANDEMIC AS CONTROL VARIABLE
Authors: Anas Dadio Fiasani , Ismawati Anastasia Filiana 
Published: January 2023

The COVID-19 pandemic has caused nationwide economic losses. This condition forces companies to try keeping financial performance stable. What needs to be watched out for during this pandemic is hiding or manipulating company financial statements to improve investors’ interest in investing on the company during this pandemic. Before the pandemic, financial statement fraud cases had often occurred in Indonesia, such as cases of auditor failure, companies revising financial statements, or manipulating false claims to get rewards. This study aims to determine the relationship between financial stability, external pressure, financial targets, ineffective monitoring, change of auditors, and change of directors on financial statement fraud. The sample of this research is pharmaceutical companies listed on the Indonesia Stock Exchange for the period of 2018–2021.This study uses secondary data sources originating from the company’s financial statements. The results of the study stated that financial stability, financial target, change of auditor, and change of director had no effect onfinancial statement fraud. External pressure has a positive effect on financial statement fraud, while ineffective monitoring has a negative effect on financial statement fraud.
Keywords: financial statement fraud, pandemic, fraud diamond, pharmacy.
THE EFFECT OF USING ELSA (ENGLISH LANGUAGE SPEECH ASSISTANT) SPEAK APPLICATION ON STUDENTS’ SPEAKING ABILITY FOR THE ELEVENTH GRADE OF MAS DARUL AL MUHAJIRIN IN THE ACADEMIC YEAR 2021/2022
Authors: Aswaty Puja , Indari Ayu 
Published: January 2023

This research was conducted to the eleventh grade students of of MAS Darul Al Muhajirin in the academic year 2021/2022. This was an experimental research which used two group pre-test and post-test designs. The sample of research was 40 divided by two classes, XI-MIPA 2 as experimental class and XI-MIPA 1 as control class. This research was conducted to know the positive effect of using ELSA Speak Application on students’ speaking ability. Based on the students’ problems such as students worked hard to produce the English expression, students pronounced the words of the expression in inexact way, student used wrong intonation and stress in sounding the English expression. Having analyzed the data of pre-test and post-test by using t-test, from the result of calculation, it was obtained the value of the t-test was 10,619. The degree of freedom is 38 (df = because there was not df 38 in the t-table, so the writers decide to use df 40 since it was closer to 38 that df 30. The table at df 40 showed that the value of t-table ( was 2,02 for 5% and 2,70 for 1%. This result meant that the value of t-test was not appropriate with the criteria of acceptance of Ho, because the fact showed the value of t-test was higher than t-table (2,02 < 10,619 > 2,70). So, from that explanation, writers concluded that null hypothesis was rejected and alternative hypothesis was accepted. Hence, hypothesis stated that there was a significant effect of using ELSA (English Language Speech Assistant) Speak Application on students’ speaking ability for the eleventh grade of MAS Darul Al Muhajirin in the academic year 2021/2022.
COVID-19 in people living with HIV: a single-center descriptive study
Authors: Pérez-Barragán Edgar , Castillo-Flores José Humberto , Mata-Marín José Antonio , Franco López Sara Gabriela , Morales Martínez Brian Alexis , Pérez Cavazos Samantha 
Published: January 2023

Introduction: People living with human immunodeficiency virus (PLHIV) may suffer more severe symptoms of coronavirus disease 2019 (COVID-19) due to their immunocompromised status, even if they are undetectable. Human immunodeficiency virus (HIV) infection has been reported as an independent factor associated with higher mortality in patients with COVID-19. The present study aims to describe the clinical characteristics of PLHIV and COVID-19 in one center in Mexico.
Methodology: We conducted an observational retrospective monocentric cohort study of PLHIV diagnosed with COVID-19 between 1 March 2020 and 30 April 2021. SARS-CoV-2 was detected by polymerase chain reaction (PCR) of a nasopharyngeal swab sample, clinical features, and epidemiological characteristics.
Results: We identified 55 PLHIV with COVID-19. The median age was 36 years (IQR 25–41.5 years), and 54 patients were men. The median duration of HIV-1 infection was 4.3 years (Interquartile range, IQR 2.6–7.2 years), and 100% were on antiretroviral therapy (ART). The last HIV-1 RNA viral load analysis of the patients was 52/55 (94.5%) indicating that they were in virological suppression. The median CD4+ T-cell count was 734/mm3 (IQR 541.5-921/mm3). The most frequent pre-existing comorbidities found were obesity (21.8%), hypertension (7.2%), and diabetes (5.4%). Only one death was reported (1.8%).
Conclusions: It has been reported that COVID-19/HIV/AIDS co-infection has a higher risk of mortality, admission to intensive care, and complications. However, our study found that people living with HIV-1 with adequate virological control did not present a severe course of COVID -19.
Susceptibility of carbapenem-resistant Enterobacterales isolates to new antibiotics from a tertiary care hospital, Egypt: A matter of hope
Authors: G Badran Shahenda , Malek Mai M , M Ateya Rehab , Afifi Amira H , Magdy Mahmoud M , Elgharabawy Eman S 
Published: January 2023

Introduction: Carbapenem-resistant Enterobacterales (CRE) are particularly worrisome pathogens because of their resistance to last-resort antibiotics, significant morbidity, and mortality. With limited treatment options, new therapeutic choices have become available for the management of CRE infections. Data regarding the efficacy of these novel agents are still limited particularly in a low-middle-income country like Egypt. This study aims to assess the prevalence of different carbapenemase genes among CRE isolates and the susceptibility of these isolates to novel antibiotics for improving antibiotic policy and infection control strategies in Egypt.
Methodology: In this cross-sectional study, 260 Enterobacterales were recovered from patients admitted to intensive care units between January and June 2021. Susceptibility testing was conducted using Kirby-Bauer method. Molecular detection of five carbapenemase genes, namely blaKPC, blaIMP, blaVIM, blaNDM, blaOXA-48 was done using polymerase chain reaction (PCR).
Results: Of the 260 Enterobacterales, 34.6% were found to be carbapenems resistant. All of the CRE isolates were multi-drug resistant exhibiting resistance to most antibiotics. All isolates harbored one or more carbapenemases genes. The most prevalent was blaNDM (84.4%), followed by blaOXA-48 (73.3%), blaKPC (13.3%), blaIMP (2.2%), while blaVIM gene wasn’t detected. Among 62.2% of the CRE isolates, two or more carbapenemase genes co-existed. For the new antibiotics tested, 100% of CRE resisted ceftolozane/tazobactam, 86.7% resisted ceftazidime/avibactam, 51.1% were resistant to eravacyclin, and 42.2% were resistant to cefiderocol.
Conclusions: A high percentage of resistance to carbapenems among Enterobacterales isolates was revealed. blaNDM was found to be the most predominant carbapenemase gene. A high rate of CRE resistance to novel agents signifies a major threat.
Influences of Problem-Based Online Learning on the Learning Outcomes of Learners
Authors: Zhang Chi 
Published: January 2023

Abstract—Influenced by the COVID-19 pandemic, online learning has become a major learning mode for most university students in China. For high-quality online teaching, teachers must optimize the teaching mode and strengthen the enthusiasm of students in classroom learning. In this study, a comparative experiment was carried out based on the course Cross-border E-commerce Customer Services for sophomore E-commerce majors at Huanghuai University in Zhumadian City, Henan Province, China. In the experiment, the teaching effect of the problem-based learning (PBL) mode in higher education was verified and gender differences in learning outcomes of learners who accepted PBL were analyzed. Results showed a significant difference at the 0.01 level between pre- and post-test results of the experimental group (t=−11.367, p=0.000), proving the teaching effect of PBL. The academic performances of the experimental class are significantly better compared with those of the control class, indicating that PBL is more beneficial to improve learning outcomes of students than traditional teaching methods. Gender has significant influences on post-test results at the 0.01 level (p=0.002<0.01). The median of final exam scores of male students is obviously higher than that of female students. Research conclusions can provide important references to test the effectiveness of PBL in learning outcomes of a specific subject, construct a PBL mode that can promote deep learning, and facilitate development of university teaching from knowledge teaching to core quality training of students.
Using New Technologies and Mobiles for Students with Disabilities to Build a Sustainable Inclusive Learning and Development Ecosystem
Authors: Karagianni Eleni , Drigas Athanasios 
Published: January 2023

Nowadays, the educational policy, in many countries, promotes equal access for all students, including those with disabilities, to the general school, against all forms of social exclusion. Inclusion, in an innovative sense of the concept of diversity, focuses on the active participation and interaction of a heterogeneous student population in the general classroom. “E-inclusive” pedagogy refers to teachers’ decisions about the use of technology in the educational process with a view of compensating their developmental deficits and making functional use of their strengths. The aim of this paper is to propose tech tools and e-services for the access and active participation of students with sensory and motor disabilities in the educational procedures of the mainstream school and examine the role of teachers in realizing their inclusion / e-inclusion, as the main facilitators and modulators of the classroom settings to an open learning and development student-centered ecosystem. The results showed that teachers who accept as equal members of the school community all their students and incorporate flexibly new technologies into their teaching strategies to meet their unique needs, providing them with authentic opportunities for interaction and learning, contribute catalytically to their academic and social achievements, preparing them for substantial employment and integration opportunities in community life.
Validating a Nonlethal Method of Aging Endangered Juvenile Lost River and Shortnose Suckers
Authors: Martin Barbara A. , Burdick Summer M. , Paul-Wilson Rachael K. , Bart Ryan J. 
Published: January 2023

Abstract
Populations of imperiled Lost River Deltistes luxatus and Shortnose Chasmistes brevirostris suckers in Upper Klamath Lake, Oregon, are experiencing long-term decreases in abundance due to limited recruitment of juvenile suckers into the adult populations. Researchers use estimated ages based on fin rays to study environmental factors affecting year-class formation, generate annual juvenile sucker survival indices, and study variations in early life history. Biased or imprecise age estimates can lead to erroneous conclusions and have implications for age-based survival estimates, indications of recruitment, and growth estimators. We examined fin rays collected from individual suckers captured on multiple occasions and determined that juvenile suckers deposit a translucent increment on fin rays annually. Size-at-age data for suckers first captured as young as age 0 corroborated our finding of annual increment formation and indicate that the first increments are formed at age 1. We used edge and marginal increment analysis conducted on fin rays to determine the timing of annual increment formation. Our results indicate that increment formation occurs on fin rays of juvenile suckers from October to May and peaks between February and April.