bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bridging distance through zooming? The use of virtual assignments in multinational corporations
Authors: Wicht Luisa , Holtbrügge Dirk 
Published: April 2023

PurposeVirtual assignments, in which the virtual assignees do not relocate to host locations, but work remotely, have several advantages compared to traditional international assignments, such as enhanced flexibility, cost-efficiency and the possibility that virtual assignees can stay in their home communities. However, it is open to question whether virtual assignments are as effective as traditional assignments. The purpose of this study is to compare the ability of virtual vs traditional assignees to bridge the distance between headquarters and subsidiaries.Design/methodology/approachBased on a survey among virtual and traditional assignees, the ability to bridge multiple facets of distance is examined.FindingsThe results indicate that virtual and traditional assignees have similar abilities to bridge geographic, cultural, functional and language distance. However, traditional assignees have a higher ability to bridge emotional and temporal distance.Originality/valueBy applying the distance framework to virtual assignments, a new theoretical perspective is introduced and the importance of clearly disentangling distance-bridging abilities is highlighted. One practical recommendation is that, due to lower costs and reduced coordination efforts required for virtual assignments, this assignment type is preferable if the cultural, language, functional and geographic distances are the most problematic ones during international assignments.
Self-service technology recovery: the importance of psychological need support
Authors: Keating Byron W. , Aslan Marjan 
Published: April 2023

PurposeThe service recovery literature provides little guidance to firms on how users of self-service technology (SST) perceive assistance provided by human and non-human service agents following a service obstacle. This research responds by addressing two important research questions about SST recovery: (1) how are perceptions of assistance provided following a service obstacle influenced by a customer's psychological needs? and (2) does supporting the psychological needs of customers positively impact continuance intentions following a service obstacle?Design/methodology/approachData are collected to address the research questions via five experiments that explore how assistance provided by a non-human (vs human vs no assistance) service agent contributes to perceptions of psychological support and continuance intentions following a service obstacle while volitionally using SST.FindingsThe results show that while users of SST would prefer to do so without an obstacle requiring intervention of a service agent, if assistance is required then the psychological need support elicited from a non-human service agent was vital to an effective recovery. Further, the findings highlight some boundary conditions for this relationship, with the impact of customer perceived need support on continuance intentions found to be sensitive to fit between the task and assistance provided and the complexity of the task being completed.Originality/valueMuch of the prior service recovery literature has emphasized the different types of tactics that can be used (e.g. apologizing, monetary compensation and explaining what happened), failing to appreciate the role of different types of service agents or the underlying psychological process that explain the relative merit of such tactics. The present research shows that for these tactics to influence continuance intentions, they must be provided by a relevant service agent and support a customer's psychological need for autonomy, competence and relatedness. The hypothesized impact of psychological need support on continuance intentions was also observed to be contingent upon the fit between the task and the type of assistance provided, where the level of task complexity attenuated this fit.
Evidence, hints and assumptions for late pregnancy in the Ancient Mediterranean and Near East
Authors: Malamitsi‐Puchner Ariadne , Konstantakos Ioannis M. 
Published: April 2023

AbstractAncient women, who survived childhood mortality, received good and adequate nutrition, did not work hard and escaped death during childbirth could live fairly long lives. Girls started procreation after marriage, usually at 15 years, had on average seven children, childbearing lasted 14–21 or more years and could happen at the age of 35 or more years. Breastfeeding, usually with contraceptive effect, continued for 2–3 years. Limited actual facts, written evidence and findings, but several hints, assumptions and logical conclusions from secular texts, sacred books, narratives and myths suggest the possibility of late childbearing in the Mediterranean and Near‐Eastern ancient world, particularly for the Jews.
Electroacupuncture alleviated depression‐like behaviors in ventromedial prefrontal cortex of chronic unpredictable mild stress‐induced rats: Increasing synaptic transmission and phosphorylating dopamine transporter
Authors: Cai Xiaowen , Wu Mei , Zhang Zhinan , Liu Huacong , Huang Shengtao , Song Jia , Ren Siqiang , Huang Yong 
Published: April 2023

AbstractAimsElectroacupuncture (EA) shows advantages in both clinical practice and depression animal models. Dopaminergic‐related dysfunction in the prefrontal cortex (PFC) may be a hidden antidepressant mechanism of EA, where dopamine transporter (DAT) plays an essential role. This study aimed to investigate the synaptic transmission and DAT‐related changes of EA in depression.MethodsMale Sprague–Dawley rats were subjected to 3‐week chronic unpredictable mild stress (CUMS). The successfully modeled rats were then randomly and equally assigned to CUMS, selective serotonin reuptake inhibitor (SSRI), and EA or SSRI + EA groups, followed by a 2‐week treatment respectively. After monitoring body weight and behavioral tests of all rats, the ventromedial PFC (vmPFC) tissue was collected for electrophysiology and the expression detection of DAT, phosphorylated DAT (p‐DAT), cyclic adenosine monophosphate (cAMP), protein kinase A (PKA), and trace amine‐associated receptor 1 (TAAR1).ResultsDepressive‐like behaviors induced by CUMS were alleviated by EA, SSRI, and SSRI + EA treatments through behavioral tests. Compared with CUMS group, EA improved synaptic transmission in vmPFC by upregulating spontaneous excitatory postsynaptic currents amplitude. Molecularly, EA reversed the increased total DAT and p‐DAT expression as well as the decreased ratio of p‐DAT/total DAT along with the activation of TAAR1, cAMP, and PKA in vmPFC.ConclusionWe speculated that the antidepressant effect of EA was associated with enhanced synaptic transmission in vmPFC, and the upregulated phosphorylation of DAT relevant to TAAR1, cAMP, and PKA may be the potential mechanism.
Including genotypic information in genetic evaluations increases the accuracy of sheep breeding values
Authors: Kaseja Karolina , Mucha Sebastian , Smith Ed , Yates John , Banos Georgios , Conington Joanne 
Published: April 2023

AbstractThe impact of inclusion of genome‐wide genotypes into breeding value predictions for UK Texel sheep is addressed in this article. The main aim was to investigate the level of change in the accuracy values for EBVs when information from animal genotypes is incorporated into the genetic evaluations. New genetic parameters for a range of lamb growth, carcass composition and health traits are described and applied in the estimation of conventional breeding values (EBVs) for almost 822,000 animals as well as genomic breeding values (gEBVs) after adding 10,143 genotypes. Principal component analyses showed that there are no major distinct groups; hence, the population is mainly homogenous and genetically well‐linked. Results suggested that the highest change in accuracy was observed for the animals that are not phenotyped but have good links to the reference population. This was seen especially for the lowly heritable health traits thereby proving that the use of genotypes in breeding values estimation may accelerate the genetic gain by producing more accurate values especially for young, un‐phenotyped animals.
Patient satisfaction and oral health‐related quality of life for four implant‐assisted mandibular overdentures fabricated with CAD/CAM milled poly methyl methacrylate, CAD/CAM‐milled poly ether ether ketone, or conventional poly methyl methacrylate: A crossover clinical trial
Authors: Gomaa Amira M. , Mostafa Aisha Z. H. , El‐Shaheed Noha H. 
Published: April 2023

AbstractBackgroundNew materials for overdenture base construction were evolved. Thus, more clinical trials are needed to validate these materials.ObjectiveThis study aimed to compare the difference between CAD/CAM‐milled poly methyl methacrylate (PMMA), poly ether ether ketone (PEEK) and conventional mandibular implant‐assisted overdentures regarding patient satisfaction and oral health‐related quality of life (OHRQL).MethodsThis randomised, crossover, clinical study included 18 completely edentulous subjects rehabilitated with three mandibular implant‐assisted overdentures with three different denture base materials opposing a maxillary single denture. These materials were as follows: CAD/CAM‐milled PMMA, CAD/CAM‐milled PEEK and conventional PMMA. Every participant first received each mandibular overdenture in a random manner. After 6 months of each overdenture use, patient satisfaction and oral health‐related quality of life were assessed using visual analogue scale (VAS) and Oral Health Impact Profile (OHIP‐EDENT‐19), respectively, and then crossover to other groups was done. The same was repeated to the last group. Comparison of VAS and OHIP‐EDENT‐19 between groups was done using Kruskal–Wallis test followed by Bonferroni test.ResultsRegarding all the VAS items, there were statistically significant higher scores for CAD/CAM‐milled PMMA and PEEK than conventional PMMA base except for speech, aesthetic and smell. Regarding OHIP‐EDENT‐19, many items revealed statistically lower problem scores for CAD/CAM‐milled PMMA, and CAD/CAM‐milled PEEK than conventional PMMA base except psychological discomfort, psychological disability and social disability.ConclusionWithin the limit of this study, CAD/CAM‐milled PMMA and CAD/CAM‐milled PEEK were recommended as implant‐assisted overdenture bases as it revealed higher patient satisfaction and better oral health‐related quality of life in comparison with conventional PMMA implant‐assisted overdenture.
The catalog of the meteorite collection of the Italian Museum of Planetary Sciences in Prato (Italy)
Authors: Morelli Marco , Franza Annarita , Faggi Daniela , Pratesi Giovanni 
Published: April 2023

AbstractFor the first time, this paper presents to the planetary scientists' community the catalog of the meteorite collection preserved at the Italian Museum of Planetary Sciences (Museo Italiano di Scienze Planetarie, henceforth MISP) in Prato (Italy). Founded in 2005, MISP is a type specimen official repository approved by the Nomenclature Committee of the Meteoritical Society. It represents one of the few museums worldwide entirely devoted to planetary sciences. The catalog of its meteorite collection encompasses 430 meteorites for a total of 1536 specimens, including 291 thin sections, 184 thick sections, and 278 specimens that MISP has classified. Furthermore, MISP is currently classifying 57 other meteorites. Some samples were found during meteorite recovery expeditions in hot deserts, promoted by MISP in collaboration with diverse Italian universities and national research institutions. MISP also keeps an impact rocks collection comprising 257 samples. In a country like Italy, where most of the collected meteorites are housed in museums whose catalogs are not available online, the publication of the MISP meteorite collection catalog, together with the catalog of the impact rocks collection, represents not only a significant scientific primary source but also a remarkable tool for disseminating meteoritics to nonresearch audiences in educational activities and citizen science projects.
Toward a critical social ontology
Authors: Thompson Michael J. 
Published: April 2023

AbstractI argue in this paper for a critical social ontology, or an approach to theorizing social reality and social institutions that is more than descriptive of social reality, but is also able to provide practical reasoning with an ontological dimension for judgment. At the heart of this idea is a different take on social metaphysics from most standard current accounts in that it begins with empirical, phylogenetic capacities of human beings for social practices (realizing abstract thought in the world) as well as relationality (the need for attachments to others). The combination of these two essential human capacities, what I call thepractical‐relational nexus, is generative of more complex social reality. The ontogeny of any social reality is the result of the ways that this practical‐relational nexus has been organized and shaped by external social structures and systems, themselves the product of certain kinds of social power. I then explore the metaphysics of social power before considering the ways that this approach to social metaphysics can inform practical reasoning with the capacity for social and political criticism.
Supplementary Tables 1-7 from Krüppel-like Factor 4 Blocks Hepatocellular Carcinoma Dedifferentiation and Progression through Activation of Hepatocyte Nuclear Factor-6
Authors: Sun Hongcheng , Tang Huamei , Xie Dacheng , Jia Zhiliang , Ma Zhenyu , Wei Daoyan , Mishra Lopa , Gao Yong , Zheng Shaojiang , Xie Keping , Peng Zhihai 
Published: April 2023

<p>Supplementary Table S1. Primer Information for and the Genes Studied Using Real-time PCR and RT-PCR Analysis Supplementary Table S2. KLF4 Protein Expression in HCC and Matched Nontumor Tissue Specimens (n= 98*) Supplementary Table S3. Associations Between KLF4 Expression and Clinicopathological Parameters in HCC Patients Who Underwent OLT (n = 98*) Supplementary Table S4. Differences in HNF-6 Protein Expression in HCC and Matched Nontumor Tissue Specimens (n = 99) Supplementary Table S5. Association Between HNF-6 Expression and Clinicopathological Parameters in HCC Patients Who Underwent OLT (n = 99) Supplementary Table S6. Correlation Between KLF4 and HNF-6 Protein Expression in Human HCC Specimens (n = 98â€ ) Supplementary Table S7. Univrariate and Multivariate Analysis of Parameters Related to OS and RFS in HCC Patients After OLT</p>
Supplementary Figure S1-S3 from Concurrent Inhibition of Neurosphere and Monolayer Cells of Pediatric Glioblastoma by Aurora A Inhibitor MLN8237 Predicted Survival Extension in PDOX Models
Authors: Kogiso Mari , Qi Lin , Braun Frank K. , Injac Sarah G. , Zhang Linna , Du Yuchen , Zhang Huiyuan , Lin Frank Y. , Zhao Sibo , Lindsay Holly , Su Jack M. , Baxter Patricia A. , Adesina Adekunle M. , Liao Debra , Qian Mark G. , Berg Stacey , Muscal Jodi A. , Li Xiao-Nan 
Published: April 2023

<p>Supplementary Figure S1-S3 Figure S1. Anti-proliferative effects of MLN8237 on pGBM cell lines. Paired monolayer (Mono) and neurosphere (NS) of IC-4687GBM, IC-3752GBM and ICR0315GBM were seeded at 2,000 cells/well and exposed to MLN8237 (1 - 4,000 nM) and anti-proliferative effect was assessed by staining with 250 Âµg/mL of MTT for 4 hrs at day 11. Viable cells were stained with dark colored intracellular crystal. (Bar=100 Âµm) Figure S2. FCM analysis of cell cycle distribution in vitro and in vivo. A. In vitro analysis was performed in paired monolayer (Mono) and neurosphere (NS) cells of IC-4687GBM, IC-3752GBM and IC-R0315GBM. Both dose-responses (on day 7) (left panel) and time-course change (at 62.5 nM) (right panel) were examined and presented as percentages of G0 /G1 , S and G2 /M phase in alive cells. Â€ P<0.05, *P<0.01 compared to the untreated (0 nM) cells. B. In vivo changes of cell cycle distribution were analyzed in IC-4687GBM cells treated by MLN8237 (30 mg/kg/day for 12 days by gavage). In addition to the recurrent tumors (Recurrent) harvested when the mice became moribund in the survival group, a separate group of tumors harvested 1 hr post the last treatment of MLN8237 (30 mg/kg/day for 12 days by gavage) (End of Treatment samples) were also included. DNA/RNA were stained with Hoechst 33342/Pyronin Y followed by mouse antibody cocktail staining (to gate out mouse cells) and analyzed by FCM. Representative DNA/RNA profiles (upper panel) and percentage of G0 , G1 , S and G2 /M phase in cell cycle (lower panel) were presented. Figure S3. Representative images of IHC of ARUKA. A. Representative images of AURKA in IC-4687GBM xenograft showing the cells with different staining intensity (arrow) (Magnification: x40). B. AURKA protein expression in IC-R0315GBM in the vehicle treated control and in the recurrent tumor (magnification: x40).</p>
Supplementary Table 3 from High <i>BCR–ABL/GUS<sup>IS</sup></i> Levels at Diagnosis of Chronic Phase CML Are Associated with Unfavorable Responses to Standard-Dose Imatinib
Authors: Vigneri Paolo , Stagno Fabio , Stella Stefania , Cupri Alessandra , Forte Stefano , Massimino Michele , Antolino Agostino , Siragusa Sergio , Mannina Donato , Impera Stefana Stella , Musolino Caterina , Malato Alessandra , Mineo Giuseppe , Tomaselli Carmela , Murgano Pamela , Musso Maurizio , Morabito Fortunato , Molica Stefano , Martino Bruno , Manzella Livia , Müller Martin C. , Hochhaus Andreas , Raimondo Francesco Di 
Published: April 2023

<p>Supplementary Table 3.	ROC curves correlating BCR-ABL/ABL levels at diagnosis with 8-year estimates of OS, TFS, FFS, EFS and Optimal Response</p>
Supplementary Table 2 from High <i>BCR–ABL/GUS<sup>IS</sup></i> Levels at Diagnosis of Chronic Phase CML Are Associated with Unfavorable Responses to Standard-Dose Imatinib
Authors: Vigneri Paolo , Stagno Fabio , Stella Stefania , Cupri Alessandra , Forte Stefano , Massimino Michele , Antolino Agostino , Siragusa Sergio , Mannina Donato , Impera Stefana Stella , Musolino Caterina , Malato Alessandra , Mineo Giuseppe , Tomaselli Carmela , Murgano Pamela , Musso Maurizio , Morabito Fortunato , Molica Stefano , Martino Bruno , Manzella Livia , Müller Martin C. , Hochhaus Andreas , Raimondo Francesco Di 
Published: April 2023

<p>Supplementary Table 2.	Outcome comparison in patients recruited to the IRIS, German CML IV and SCREEN studies</p>
Supplementary Figure 5 from High <i>BCR–ABL/GUS<sup>IS</sup></i> Levels at Diagnosis of Chronic Phase CML Are Associated with Unfavorable Responses to Standard-Dose Imatinib
Authors: Vigneri Paolo , Stagno Fabio , Stella Stefania , Cupri Alessandra , Forte Stefano , Massimino Michele , Antolino Agostino , Siragusa Sergio , Mannina Donato , Impera Stefana Stella , Musolino Caterina , Malato Alessandra , Mineo Giuseppe , Tomaselli Carmela , Murgano Pamela , Musso Maurizio , Morabito Fortunato , Molica Stefano , Martino Bruno , Manzella Livia , Müller Martin C. , Hochhaus Andreas , Raimondo Francesco Di 
Published: April 2023

<p>Figure 5.	Nomograms predicting eight-year FFS probabilities according to BCR-ABL/GUSIS expression at diagnosis and the Sokal (panel A) or Hasford (panel B) prognostic scores were generated by stratifying patients for these variables and then using a modified Cox proportional hazard model. Differences observed between the various patient subgroups were statistically significant (p<0.001).</p>
Supplementary Figure 4 from High <i>BCR–ABL/GUS<sup>IS</sup></i> Levels at Diagnosis of Chronic Phase CML Are Associated with Unfavorable Responses to Standard-Dose Imatinib
Authors: Vigneri Paolo , Stagno Fabio , Stella Stefania , Cupri Alessandra , Forte Stefano , Massimino Michele , Antolino Agostino , Siragusa Sergio , Mannina Donato , Impera Stefana Stella , Musolino Caterina , Malato Alessandra , Mineo Giuseppe , Tomaselli Carmela , Murgano Pamela , Musso Maurizio , Morabito Fortunato , Molica Stefano , Martino Bruno , Manzella Livia , Müller Martin C. , Hochhaus Andreas , Raimondo Francesco Di 
Published: April 2023

<p>Figure 4.	Evolution of BCR-ABL/ABL transcripts in CML patients displaying high (A) or low (B) BCR-ABL/GUSIS levels at diagnosis according to the FFS threshold indicated in Table 1. Asterisks in the upper graph indicate confirmed transcript values in two separate samples collected one month apart.</p>
Supplementary Figure 3 from High <i>BCR–ABL/GUS<sup>IS</sup></i> Levels at Diagnosis of Chronic Phase CML Are Associated with Unfavorable Responses to Standard-Dose Imatinib
Authors: Vigneri Paolo , Stagno Fabio , Stella Stefania , Cupri Alessandra , Forte Stefano , Massimino Michele , Antolino Agostino , Siragusa Sergio , Mannina Donato , Impera Stefana Stella , Musolino Caterina , Malato Alessandra , Mineo Giuseppe , Tomaselli Carmela , Murgano Pamela , Musso Maurizio , Morabito Fortunato , Molica Stefano , Martino Bruno , Manzella Livia , Müller Martin C. , Hochhaus Andreas , Raimondo Francesco Di 
Published: April 2023

<p>Figure 3.	Eight-year estimates of OS (A), TFS (B), FFS (C) and EFS (D) in CML patients expressing high or low BCR-ABL/ABL at diagnosis. The endpoint-specific BCR-ABL/ABL thresholds identified in Supplementary Table 3 were used to divide patients in two groups exhibiting high (dashed line) or low (solid line) BCR-ABL transcripts. Higher BCR-ABL levels were associated with significantly inferior rates of FFS (p<0.005) and EFS (p=0.001) but not OS and TFS. Vertical lines indicate censored patients.</p>
FigureS4 from Early Evaluation of Circulating Tumor DNA as Marker of Therapeutic Efficacy in Metastatic Colorectal Cancer Patients (PLACOL Study)
Authors: Garlan Fanny , Laurent-Puig Pierre , Sefrioui David , Siauve Nathalie , Didelot Audrey , Sarafan-Vasseur Nasrin , Michel Pierre , Perkins Geraldine , Mulot Claire , Blons Hélène , Taieb Julien , Di Fiore Frederic , Taly Valerie , Zaanan Aziz 
Published: April 2023

<p>Supplementary Figure 4. Impact on Progression free survival (PFS) of the slope of decrease of ctDNA concentration (SlopeÃ¢Ë†â€ ctDNA, {greater than or equal to}80% or <80%) in the D{greater than or equal to}0.1ng/mL group.</p>
Table S1, Table S2 from Phase Ib Study of Lumretuzumab Plus Cetuximab or Erlotinib in Solid Tumor Patients and Evaluation of HER3 and Heregulin as Potential Biomarkers of Clinical Activity
Authors: Meulendijks Didier , Jacob Wolfgang , Voest Emile E. , Mau-Sorensen Morten , Martinez-Garcia Maria , Taus Alvaro , Fleitas Tania , Cervantes Andres , Lolkema Martijn P. , Langenberg Marlies H.G. , De Jonge Maja J. , Sleijfer Stefan , Han Ji-Youn , Calles Antonio , Felip Enriqueta , Kim Sang-We , Schellens Jan H.M. , Wilson Sabine , Thomas Marlene , Ceppi Maurizio , Meneses-Lorente Georgina , James Ian , Vega-Harring Suzana , Dua Rajiv , Nguyen Maitram , Steiner Lori , Adessi Celine , Michielin Francesca , Bossenmaier Birgit , Weisser Martin , Lassen Ulrik N. 
Published: April 2023

<p>Supplementary Table 1	Downregulation of HER3 membrane protein expression in skin biopsies following treatment with lumretuzumab and cetuximab or erlotinib Supplementary Table 2	Change of tumor biomarkers in tumor biopsies following treatment with lumretuzumab and cetuximab or erlotinib</p>
Supplementary Figure S3 from Validation of the 16-Gene Recurrence Score in Patients with Locoregional, High-Risk Renal Cell Carcinoma from a Phase III Trial of Adjuvant Sunitinib
Authors: Rini Brian I. , Escudier Bernard , Martini Jean-Francois , Magheli Ahmed , Svedman Christer , Lopatin Margarita , Knezevic Dejan , Goddard Audrey D. , Febbo Phillip G. , Li Rachel , Lin Xun , Valota Olga , Staehler Michael , Motzer Robert J. , Ravaud Alain 
Published: April 2023

<p>Kaplan-Meier estimates for RCSS by RS risk group in (A) placebo arm and (B) sunitinib arm. *Log-rank test for high vs low RS risk groups. â€ No events observed by 5 years. Abbreviations: CI, confidence interval; RCCS, renal cancer-specific survival; RS, recurrence score.</p>