bluuebunny/crossref_metadata_2025_split huggingface dataset:
paridad género en los comités editoriales
Authors: Ferrer Carolina 
Published: July 2023

El objetivo de este trabajo fue analizar el rol de la mujer en la gestión editorial de las publicaciones periódicas digitales editadas por la Universidad Nacional del Centro de la Provincia de Buenos Aires (UNCPBA), Argentina. Se realizó un estudio de datos comparativos desde una perspectiva de género en relación con la paridad en el ámbito de la representación y conformación teniendo en cuenta las siguientes dimensiones vinculadas con el ecosistema editorial: a) editoras y editores, b) directoras y directores, c) comités editoriales, d) comités científicos, sobre un total de dieciséis (16) publicaciones periódicas en su mayoría correspondientes a las áreas de las Ciencias Sociales y Humanidades (CSyH) y Ciencias Exactas y de la Tierra (CEyN) pertenecientes a cinco (5) unidades académicas de la Universidad, dado que no todas cuentan con revistas de estas características. Asimismo, se analizaron de las publicaciones las características de accesibilidad, visibilidad integral e indizaciones que acreditan la calidad de sus producciones científicas y editorial visualizadas en la labor de liderazgo y gestión mayoritariamente realizadas por docentes e investigadoras.
Recepción: 13/9/2022. Aceptación: 17/4/2023. Publicación: 27/6/2023
literatura feminista y entrerriana
Authors: Delaloye María Fernanda 
Published: July 2023

Este artículo propone una lectura en clave de crítica feminista de Lengua Montaraz (2021) y Las armas (2021), los títulos más recientes y celebrados de la autora paranaense Belén Zavallo. En el último tiempo mujeres y disidencias han ocupado un lugar preponderante en el campo cultural a nivel latinoamericano, nacional y provincial. Sus textos abren camino y reactualizan los diferentes espacios en los que se insertan mujeres y disidencias dentro del campo de la producción simbólica; constituyen un agenciamiento desde un marco discursivo propio, contrahegémónico y genderizado. En este lugar se inscriben las publicaciones de Zavallo analizadas.
En la poesía y en la narrativa de Zavallo aparecen puntos de fuga que perforan el formato reglamentario de la cultura masculino-paterna-hegemónica a partir diversas esferas: desde la perspectiva de género, puesto que reivindica los lugares tradicionalmente menores, la poesía y la narrativa del Yo; desde el punto de vista temático ya que muestra la violencia sexista desde la singularidad que habilita el uso de la primera persona; y, por último, desde su posicionamiento como intelectual comprometida con la causa feminista. Concibe la literatura como una tecnología, un arma de género que le permite construir un dispositivo de enunciación que articula lo individual con lo colectivo.
Recepción: 5/12/22. Aceptación: 6/4/2023. Publicación: 27/6/2023
Quiste aracnoideo intracraneal a causa de trauma craneoencefálico en paciente pediátrico. Reporte de caso
Authors: Sarango Feijoó Angie Carolina , Ochoa Aucay Jorge Eduardo , Robles Delgado María Cristina 
Published: July 2023

Introducción. Los quistes aracnoideos son lesiones benignas llenos de líquido cefalorraquídeo revestidos por una membrana aracnoidea. Su asociación con traumatismos craneoencefálicos se informa con poca frecuencia. Choi y Kim fueron los primeros en postular que el traumatismo craneoencefálico en la infancia puede en algunos casos contribuir a su patogenia. Objetivo. Describir el caso de un paciente pediátrico con deformidad craneal ósea en región temporal izquierda que se hizo evidente posterior a un traumatismo craneoencefálico en la misma zona, el manejo quirúrgico empleado y su evolución. Metodología. La metodología a utilizar será reporte de caso, la recolección de información se desarrolló de manera retrospectiva por medio del acceso a la historia clínica física y digital del paciente con previa autorización de los representantes legales por medio del consentimiento informado. Resultados. Paciente pediátrico de 2 años 2 meses con deformidad craneal temporal izquierda que se hizo evidente posterior a traumatismo craneoencefálico. En la tomografía de cráneo se observó una lesión quística de gran tamaño en región temporal izquierda que remodela la calota adyacente. La tomografía de control a los 3 meses del posoperatorio mostró reducción significativa y un nuevo hallazgo de un higroma subdural. Conclusión. Un traumatismo craneoencefálico podría ser un factor determinante involucrado en la patogenia del quiste aracnoideo, sin embargo, se requiere de un mayor abordaje del tema. Área de estudio general: Medicina. Área de estudio específica: Neurología.
ANALISIS PERAN BADAN PENGAWAS PEMILU DALAM PENEGAKAN HUKUM PEMILU
Authors: Syafriadi Syafriadi , Santri Selvi Harvia 
Published: July 2023

The Election Supervisory Body (Bawaslu) has a role in maximizing the quality of the implementation of elections so as to provide certainty for the upholding of sovereignty and the pure results of the votes that will be cast by the community. Regulations for regulating the authority regarding Bawaslu in Indonesia are regulated in Law Number. 2 of 2015, this rule regulates the role and duties of Bawaslu, one of which is as a structure in election supervision related to law enforcement in the holding of elections. Bawaslu has very limited duties in carrying out its role as an election organizer, there is always news that mentions the weak supervision carried out by Bawaslu in holding elections. Community expectations for Bawaslu in carrying out their role are very high, but, on the other hand, the limited authority given to Bawaslu makes their role dysfunctional. The ineffectiveness of the duties carried out by Bawaslu will affect the implementation of the election administration. The purpose of this study is to examine and examine the role of Bawaslu in carrying out their duties in supervising the implementation of elections in society. The method used in this research is normative legal research. Bawaslu has roles and duties that have been regulated in laws and regulations, namely overseeing the stages of the election implementation process with regard to efforts to prevent prosecution of violations that occur in elections.AbstrakBadan Pengawas Pemilu (Bawaslu) memiliki peran dalam hal memaksimalkan kualitas pelaksanaan penyelenggaraan Pemilu sehingga memberikan kepastian untuk tegaknya kedaulatan dan murninya hasil suara masyarakat. Peraturan untuk mengatur kewenangan mengenai Bawaslu di Indonesia diatur pada UU Nomor 2 tahun 2015, aturan ini mengatur peran dan tugas Bawaslu, salah satunya sebagai struktur dalam pengawasan Pemilu yang berkaitan dengan hal penegakan hukum pada penyelenggaraan Pemilu. Bawaslu memiliki tugas yang sangat terbatas dalam menjalankan peran sebagai pelaksanaan Pemilu. Ada saja berita yang menyebutkan lemahnya pengawasan yang dilakukan bawaslu dalam penyelenggaaan pemilu. Harapan masyarakat terhadap bawaslu dalam menjalankan perannya sangatlah tinggi, tetapi, di sisi lain, keterbatasan kewenangan yang diberikan kepada Bawaslu menjadikan perannya tidak berfungsi. Ketidakefektifan tugas yang dilakukan Bawaslu akan mempengaruhi pelaksanaan penyelenggaraan Pemilu. Tujuan penelitian ini adalah untuk mengkaji dan menelaah peran Bawaslu dalam melaksanakan tugasnya dalam pengawasan pelaksanaan penyelenggaraan Pemilu di masyarakat. Metode yang digunakan dalam penelitian ini adalah jenis penelitian hukum normatif. Hasil penelitian menunjukkan bahwa Bawaslu memiliki peran dan tugas yang telah diatur dalam peraturan perundang-undangan yaitu mengawasi tahapan proses pelaksanaan Pemilu yang berkenaan dengan upaya pencegahaan penindakan pelanggaran yang terjadi dalam Pemilu.
Pengaruh Pendidikan Kesehatan Pada Tingkat Pengetahuan Ibu Post Partum Tentang Senam Nifas
Authors: Nurbaiti Meta 
Published: July 2023

Salah satu cara agar kontraksi uterus tetap sehat bisa dengan olahraga sederhana, olahraga yang bisa digunakan adalah senam nifas. Karena pada saat senam nifas, otot rahim mengalami kontraksi dan kontraksi yang menyebabkan pembuluh darah di rahim mengencang dan menyempit untuk mencegah pendarahan. Tujuan penelitian ini untuk mengetahui pengaruh Pendidikan Kesehatan Pada Tingkat Pengetahuan Ibu Post Partum Tentang Senam Nifas. Desain penelitian yang digunakan adalah pendekatan one group pre test dan post test only desaign. Sampel dalam penelitian ini yaitu ibu post partum sebanyak 32 orang. Sampel diambil secara accidental samling pengambilan data dengan menggunakan kuesioner. Hasil penelitian ini dianalisis dengan menggunakan analisis bivariat menggunakan uji wilcoxon. Hasil penelitian ini menunjukkan distribusi frekuensi pengetahuan ibu post partum sebelum diberikan pendidikan kesehatan sebagian besar berpengetahuan kurang yaitu sebanyak 20 sampel (62,5%). Distribusi frekuensi pengetahuan ibu post partum sesudah diberikan pendidikan kesehatan sebagian besar berpengetahuan baik yaitu sebanyak 28 sampel (87,5%). Ada perbedaan yang signifikan pengetahuan ibu post partum sebelum dan sesudah diberikan pendidikan kesehatan dengan p value 0,002 (< 0,05). Diharapkan petugas kesehatan lebih banyak memberikan edukasi kepada ibu post partum tentang manfaat senam nifas.
Development and validation of the motivation to publish scale-scientific articles (EMP-AC) for Peruvian university students
Authors: Mamani-Benito Oscar , Torres-Miranda Julio , Apaza-Tarqui Edison Effer , Tito-Betancur Madona , Morales-García Wilter C. , Turpo-Chaparro Josué Edison 
Published: July 2023

ObjectiveTo design and validate the motivation to publish scale-scientific articles (EMP-AC) for Peruvian university students.MethodsThis was an instrumental study in which 653 health, business, humanities and engineering students from private and state universities in the 3 regions of Peru participated. The scale was designed in 5 stages following international standards. The internal structure was assessed through both an Exploratory Factor Analysis (EFA) and Confirmatory Factor Analysis (CFA).ResultsThe content analysis by expert judges also supported the representativeness of the items related to the construction. The internal structure of the 13-item scale was confirmed through the Exploratory Factor Analysis (EFA) and Confirmatory Factor Analysis (CFA) which showed a structure of three factors: commitment, behavior, and intentional state as initially proposed. Previous analyses of goodness of fit indices were satisfactory (χ2 (167) = 276.93, p  &lt;  0.001; CFI = 0.95; TLI = 0.93; RMSEA = 0.07 [0.06–0.08]; SRMR = 0.06).ConclusionThe EMP-AC shows initial evidence of validity and reliability; therefore, it can be applied in the study of the motivation to publish scientific articles by Peruvian university students.
Therapeutic response to pazopanib: case report and literature review on molecular abnormalities of aggressive prolactinomas
Authors: Medina Eduardo J. , Zohdy Youssef M. , Porto Edoardo , Revuelta Barbero Juan M. , Bray David , Maldonado Justin , Rodas Alejandra , Mayol Miguel , Morales Bryan , Neill Stewart , Read William , Pradilla Gustavo , Ioachimescu Adriana , Garzon-Muvdi Tomas 
Published: July 2023

IntroductionAggressive prolactinomas (APRLs) pose a significant clinical challenge due to their high rate of regrowth and potentially life-threatening complications. In this study, we present a case of a patient with an APRL who had a trial of multiple therapeutic modalities with the aim to provide a review of molecular abnormalities and management of APRLs by corroborating our experience with previous literature.MethodsA total of 268 articles were reviewed and 46 were included. Case reports and series, and studies that investigated the molecular and/or genetic analysis of APRLs were included. Special care was taken to include studies describing prolactinomas that would fall under the APRL subtype according to the European Society of Endocrinology guidelines; however, the author did not label the tumor as “aggressive” or “atypical”. Addiontionally, we present a case report of a 56-year-old man presented with an invasive APRL that was resistant to multiple treatment modalities.ResultsLiterature review revealed multiple molecular abnormalities of APRLs including mutations in and/or deregulation of ADAMTS6, MMP-9, PITX1, VEGF, POU6F2, CDKN2A, and Rb genes. Mismatch repair genes, downregulation of microRNAs, and hypermethylation of specific genes including RASSF1A, p27, and MGMT were found to be directly associated with the aggressiveness of prolactinomas. APRL receptor analysis showed that low levels of estrogen receptor (ER) and an increase in somatostatin receptors (SSTR5) and epidermal growth factor receptors (EGFR) were associated with increased invasiveness and higher proliferation activity. Our patient had positive immunohistochemistry staining for PD-L1, MSH2, and MSH6, while microarray analysis revealed mutations in the CDKN2A and POU6F2 genes. Despite undergoing two surgical resections, radiotherapy, and taking dopamine agonists, the tumor continued to progress. The patient was administered pazopanib, which resulted in a positive response and the patient remained progression-free for six months. However, subsequent observations revealed tumor progression. The patient was started on PD-L1 inhibitor pembrolizumab, yet the tumor continued to progress.ConclusionAPRLs are complex tumors that require a multidisciplinary management approach. Knowledge of the molecular underpinnings of these tumors is critical for understanding their pathogenesis and identifying potential targets for precision medical therapy.
Normalization of puberty and adult height in girls with Turner syndrome: results of the Swedish Growth Hormone trials initiating transition into adulthood
Authors: Kriström Berit , Ankarberg-Lindgren Carina , Barrenäs Marie-Louise , Nilsson Karl Olof , Albertsson-Wikland Kerstin 
Published: July 2023

ObjectiveTo study the impact of GH dose and age at GH start in girls with Turner syndrome (TS), aiming for normal height and age at pubertal onset (PO) and at adult height (AH). However, age at diagnosis will limit treatment possibilities.MethodsNational multicenter investigator-initiated studies (TNR 87-052-01 and TNR 88-072) in girls with TS, age 3–16 years at GH start during year 1987–1998, with AH in 2003–2011. Of the 144 prepubertal girls with TS, 132 girls were followed to AH (intention to treat), while 43 girls reduced dose or stopped treatment prematurely, making n=89 for Per Protocol population. Age at GH start was 3–9 years (young; n=79) or 9–16 years (old; n=53). Treatment given were recombinant human (rh)GH (Genotropin® Kabi Peptide Hormones, Sweden) 33 or 67 µg/kg/day, oral ethinyl-estradiol (2/3) or transdermal 17β-estradiol (1/3), and, after age 11 years, mostly oxandrolone. Gain in heightSDS, AHSDS, and age at PO and at AH were evaluated.ResultsAt GH start, heightSDS was −2.8 (versus non-TS girls) for all subgroups and mean age for young was 5.7 years and that of old was 11.6 years. There was a clear dose–response in both young and old TS girls; the mean difference was (95%CI) 0.66 (−0.91 to −0.26) and 0.57 (−1.0 to −0.13), respectively. The prepubertal gainSDS (1.3–2.1) was partly lost during puberty (−0.4 to −2.1). Age/heightSDS at PO ranged from 13 years/−0.42 for GH67young to 15.2 years/−1.47 for GH33old. At AH, GH67old group became tallest (17.2 years; 159.9 cm; −1.27 SDS; total gainSDS, 1.55) compared to GH67young group being least delayed (16.1 years; 157.1 cm; −1.73 SDS; total, 1.08). The shortest was the GH33young group (17.3 years; 153.7 cm: −2.28 SDS; total gainSDS, 0.53), and the most delayed was the GH33old group, (18.5 years; 156.5 cm; −1.82 SDS; total gainSDS, 0.98).ConclusionFor both young and old TS girls, there was a GH-dose growth response, and for the young, there was less delayed age at PO and at AH. All four groups reached an AH within normal range, despite partly losing the prepubertal gain during puberty. Depending on age at diagnosis, low age at start with higher GH dose resulted in greater prepubertal height gain, permitting estrogen to start earlier at normal age and attaining normal AH at normal age, favoring physiological treatment and possibly also bone health, hearing, uterine growth and fertility, psychosocial wellbeing during adolescence, and the transition to adulthood.
Development of a prediction model for neonatal hypoglycemia risk factors: a retrospective study
Authors: Wu Tian , Huang Yi-Yan , Song Wei , Redding Sharon R. , Huang Wei-Peng , Ouyang Yan-Qiong 
Published: July 2023

BackgroundIt’s challenging for healthcare workers to detect neonatal hypoglycemia due to its rapid progression and lack of aura symptoms. This may lead to brain function impairment for the newborn, placing a significant care burden on the family and creating an economic burden for society. Tools for early diagnosis of neonatal hypoglycemia are lacking. This study aimed to identify newborns at high risk of developing neonatal hypoglycemia early by developing a risk prediction model.MethodsUsing a retrospective design, pairs (470) of women and their newborns in a tertiary hospital from December 2021 to September 2022 were included in this study. Socio-demographic data and clinical data of mothers and newborns were collected. Univariate and multivariate logistic regression were used to screen optimized factors. A neonatal hypoglycemia risk nomogram was constructed using R software, and the calibration curve and receiver operator characteristic curve (ROC) was utilized to evaluate model performance.ResultsFactors integrated into the prediction risk nomogram were maternal age (odds ratio [OR] =1.10, 95% CI: 1.04, 1.17), fasting period (OR=1.07, 95% CI: 1.03, 1.12), ritodrine use (OR=2.00, 95% CI: 1.05, 3.88), gestational diabetes mellitus (OR=2.13, 95% CI: 1.30, 3.50), gestational week (OR=0.80, 95% CI: 0.66, 0.96), fetal distress (OR=1.76, 95% CI: 1.11, 2.79) and neonatal body mass index (OR=1.50, 95% CI: 1.24, 1.84). The area under the curve (AUC) was 0.79 (95% confidence interval [CI]: 0.75, 0.82), specificity was 0.82, and sensitivity was 0.62.ConclusionThe prediction model of this study demonstrated good predictive performance. The development of the model identifies advancing maternal age, an extended fasting period before delivery, ritodrine use, gestational diabetes mellitus diagnosis, fetal distress diagnosis and an increase in neonatal body mass index increase the probability of developing neonatal hypoglycemia, while an extended gestational week reduces the probability of developing neonatal hypoglycemia.
Prognosis prediction and comparison between pancreatic signet ring cell carcinoma and pancreatic duct adenocarcinoma: a retrospective observational study
Authors: Zhou Hui , Li Xiao-xue , Huang Yun-peng , Wang Yong-xiang , Zou Heng , Xiong Li , Liu Zhong-tao , Wen Yu , Zhang Zi-jian 
Published: July 2023

BackgroundPancreatic signet ring cell carcinoma (PSRCC) is a rare and aggressive cancer that has been reported primarily as case reports. Due to limited large-scale epidemiological and prognostic analyses, the outcomes of PSRCC patients varies greatly in the absence of recognized first-line treatment strategies. This study aimed to compare the clinical features, treatment, and prognosis of PSRCC and pancreatic ductal cell carcinoma (PDAC), the most common subtype of pancreatic cancer, and to establish predictive models for these subtypes.MethodsThe data on PSRCC and PDAC patients from 1998 to 2018 was obtained from the Surveillance, Epidemiology, and End Results (SEER) database. Thereafter, the clinical, demographic, and treatment characteristics of the two groups and the differences and influencing factors of the two groups were evaluated by propensity score matching (PSM), Kaplan–Meier survival curves, Cox risk regression analyses, and least absolute shrinkage and selection operator (LASSO) analysis. Next, prognosis models were constructed and validated by KM and ROC analysis. Finally, a nomogram was constructed, based on the results of these analyses, to predict survival outcomes of PSRCC and PDAC patients.ResultsA total of 84,789 patients (432 PSRCC and 84357 PDAC patients) were included in this study. The results of the study revealed that, compared to the PDAC patients, PSRCC patients were more likely to be male, aged between 58–72 years, have larger tumor masses, and less likely to undergo chemotherapy. Before PSM, the overall survival and cancer-specific survival of the PSRCC group were significantly lower than those PDAC group, but there was no difference in the prognosis of the two groups after PSM. Additionally, lymph node ratio (LNR), log odds of positive lymph node (LODDS), tumor size, age, T-stage, marital status, and summary stage were found to be independent prognostic factors for PSRCC. Lastly, the prediction model and nomogram based on these prognostic factors could accurately predict the survival rate of the patients in SEER datasets and external validation datasets.ConclusionThe prognosis of PSRCC and PDAC patients is similar under the same conditions; however, PSRCC patients may have more difficulty in receiving better treatment, thus resulting in their poor prognosis.
Kidney function and cardiovascular diseases: a large-scale observational and Mendelian randomization study
Authors: Hu Chang , Li Yiming , Qian Yaoyao , Wu Zhenying , Hu Bo , Peng Zhiyong 
Published: July 2023

BackgroundPrior observational studies have found an association between kidney function and cardiovascular diseases (CVDs). However, these studies did not investigate causality. Therefore, the aim of this study is to examine the causal relationship between kidney function and CVDs.MethodsWe utilized data from the eICU Collaborative Research Database (eICU-CRD) from the years 2014-2015 to evaluate the observational association between renal failure (RF) and CVDs. To investigate the causal effects of kidney function (estimated glomerular filtration rate [eGFR] and chronic kidney disease [CKD]) and CVDs (including atrial fibrillation [AF], coronary artery disease [CAD], heart failure [HF], any stroke [AS], and any ischemic stroke [AIS]), we conducted a two-sample bidirectional Mendelian randomization (MR) analysis.ResultsIn the observational analysis, a total of 157,883 patients were included. After adjusting for potential confounding factors, there was no significant association between baseline RF and an increased risk of developing CVDs during hospitalization [adjusted odds ratio (OR): 1.056, 95% confidence interval (CI): 0.993 to 1.123, P = 0.083]. Conversely, baseline CVDs was significantly associated with an increased risk of developing RF during hospitalization (adjusted OR: 1.189, 95% CI: 1.139 to 1.240, P &lt; 0.001). In the MR analysis, genetically predicted AF was associated with an increased risk of CKD (OR: 1.050, 95% CI: 1.016 to 1.085, P = 0.004). HF was correlated with lower eGFR (β: -0.056, 95% CI: -0.090 to -0.022, P = 0.001). A genetic susceptibility for AS and AIS was linked to lower eGFR (β: -0.057, 95% CI: -0.079 to -0.036, P &lt; 0.001; β: -0.029, 95% CI: -0.050 to -0.009, P = 0.005; respectively) and a higher risk of CKD (OR: 1.332, 95% CI: 1.162 to 1.528, P &lt; 0.001; OR: 1.197, 95% CI: 1.023 to 1.400, P = 0.025; respectively). Regarding the reverse direction analysis, there was insufficient evidence to prove the causal effects of kidney function on CVDs. Outcomes remained consistent in sensitivity analyses.ConclusionOur study provides evidence for causal effects of CVDs on kidney function. However, the evidence to support the causal effects of kidney function on CVDs is currently insufficient. Further mechanistic studies are required to determine the causality.