bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical Evaluation of Bentley 10 Plus Bubble Oxygenator
Authors: Basha J. W. , Sternlieb J.J. , Bjork V.O. , Gabrielson T. W. , Hodges V. 
Published: August 2023

This is the first clinical report evaluating the accuracy, safety and operative simplicity of the new BENTLEY 10 PLUS (B10+) bubble oxygenator to control pO2 and pCO2 independently. Eleven patients undergoing cardiopulmonary bypass (CPB) were randomly selected. The Bentley Gas Stat (BGS) was used to obtain blood gas values during CPB at five-minute intervals, (N = 270). BGS calibration values were recorded. Confirming blood gas samples were sent to the hospital laboratory at approximately 15-minute intervals to ensure accuracy of the BGS. Adjustments to the gas flow controller (GFC) and total gas flow (TGF) were made to maintain the pO2 and pCO2 with predetermined ranges, 100–150 torr and 38–42 torr, respectively. The number of adjustments required to maintain values within ranges, GFC settings, TGF settings, Hemoglobin, and visual signs of hemolysis (hemoglobin-urea) were charted.
The B10+ unique gas flow control mechanism and central filming chamber enables the user to independently control pO2 and pCO2 during CPB: thus, A) maintain blood gases within physiologic ranges, B) reduces microgaseous emboli emission, C) reduces blood trauma and D) allows blood gas control similar to a membrane at significantly less cost. Use of a continuous on-line blood gas analyzer is recommended with this oxygenator.
Intra-Aortic Balloon Counterpulsation for the Treatment of Ischemic Stroke
Authors: Berryessa Richard G. , Tranmer Bruce I. , Tyndal Charles M. , Iacobacci Raymond L. 
Published: August 2023

Colloid volume expansion has been shown to increase cerebral blood flow to ischemic brain in an animal stroke model and improve recovery in patients. It is, however, potentially hazardous to use in older patients because of frequently associated cardiovascular disease.
Intra-Aortic Balloon Counterpulsation might reduce the risks of using volume expansion therapy in the elderly patient.
This study was designed to see if Intra-Aortic Balloon Counterpulsation (without volume expansion), in an animal with a normal heart, would increase cerebral blood flow and EEG activity in the ischemic brain.
Unilateral cerebral ischemia was produced in baboons (n = 9) after right middle cerebral artery occlusion. A 12 ml intra-aortic balloon catheter was introduced into the descending aorta via the femoral artery prior to middle cerebral artery occlusion. The balloon was positioned distal to the origin of the left subclavian artery and following middle cerebral artery occlusion was inflated with each R wave on the ECG. Cardiac output, cerebral blood flow (by Hydrogen wash-out), computer-mapped EEG, and hemodynamic data were collected prior to middle cerebral artery occlusion and following occlusion both before and during counterpulsation.
Intra-Aortic Balloon Counterpulsation produced a significant increase in pulse pressure from 54.7 ± 21 to 70.6 ± 33 mmHg (p = .043). No significant change was seen in cardiac output, mean arterial pressure, or cerebral blood flow. Although the computer- mapped EEG improved and the right (ischemic) hemisphere cerebral blood flow did increase slightly from 16.9 ± 6.5 to 18.3 ± 8.3 ml/100 gm/min, the cerebral blood flow changes were not significant (p=.295).
It is possible that the desired increase in cerebral blood flow was not achieved partly because the animals were only 3-4 years old and were difficult to stroke.
We believe that there is merit to a follow-up study in older primates with colloid volume expansion where Intra-Aortic Balloon Counterpulsation is used to protect the heart from the deleterious effects of volume expansion and where the cardiac effects of volume expansion and counterpulsation are quantified.
Perhaps volume expansion with Intra-Aortic Balloon Counterpulsation will be safer and more effective than either treatment modality alone.
(All data reported as mean ± standard deviation)
Lactic Acid Generation During Pediatric Cardiopulmonary Bypass: A Comparison of Blood and Crystalloid Primes
Authors: McCormick James S. , Berryessa Richard G. , Clarke David R. , Campbell David N. , Tyndal Charles M. 
Published: August 2023

With the increasing concern over patient exposure to donor blood, we undertook a study to determine whether the exclusion of red blood cells from the pump prime for pediatric cardiopulmonary bypass surgical procedures would contribute to the development of metabolic acidosis by either decreasing O2 carrying capacity or diluting plasma buffers with a crystalloid solution. We compared a cellular (blood) prime (fresh-frozen plasma and red blood cells) and a non-cellular prime (Isolyte E and serum albumin).
Lactic acid and venous saturation levels were used to evaluate the effects of the two types of priming solutions. Lactic acid samples were drawn two minutes after bypass was initiated, and two minutes after cross clamp removal (or two minutes after bypass was resumed on circulatory arrest cases) and two minutes before discontinuing bypass. Venous saturation samples were taken at random times during the procedures. For cases using the clear prime, we were more aggressive in our blood conservation techniques.
Two-way analysis of variance revealed that there was a significant increase in lactic acid levels in both groups as a result of circulatory arrest (p = .0000000887, n = 13). There was not a significant difference in lactic acid levels between groups at any period during cardiopulmonary bypass (p =. 7756). The only differences between groups 1 (n = 15) and 2 were the bypass hematocrits, number of donor blood exposures and patient cooling times. The two-way ANOVA "Interaction" p value (p = .6117) strongly suggests that this was a clean study. These findings are supported by the comparability of the exsanguination times and venous saturations.
Our study results indicate that an Isolyte E and serum albumin prime did not increase the pediatric patient's lactic acid levels compared to a blood prime, but it does reduce patient donor blood exposure.
More Than Turning Knobs: The Expanding Role of the Clinical Perfusionist
Authors: Birenbaum Irvin B. , Rivard Dennis C. , Thompson Steven J. , Baldwin Robert C. , Banchieri Candace L. , Harple Michael S. 
Published: August 2023

The practice of clinical cardiovascular perfusion has experienced major changes in scope since its inception over thirty years ago. The tasks of today's clinical perfusionist may include not only the usual life support of patients undergoing cardiac surgery, but also such diverse duties as IABP therapy, VAD life support, artificial heart management, blood salvage for autotransfusion, rapid fluid administration, ECMO therapy, liver transplantation, circulatory support for cardiac arrest, and perfusion for distant heart-lung procurement for transplantation.
All of these duties are practiced by the perfusion team of the Johns Hopkins Medical Institutions. Except for the normal surgical tasks of a perfusion- 1st, these tasks have been assumed by the perfusion team over a recent three year period with no increase in staff. Certain managerial and team strategies were necessary to achieve this without sacrificing either patient safety or staff morale.
Perfusion Error Cause Removal: The Perfusion Case Conference
Authors: Tyndal Charles M. , Berryessa Richard G. 
Published: August 2023

Prevention of accidents is one of the fundamental elements of perfusion quality. Unfortunately, errors and accidents frequently occur during cardiopulmonary bypass. A recent retrospective survey of perfusionists identified some common accidents. We have previously reported a method of developing protocols to prevent and treat the ten most common perfusion related problems.
Until we reach the day when perfusion accidents no longer occur, we need to be able to systematically evaluate failures and prevent their recurrence.
We have developed a non-judgmental forum to discuss, analyze, and prevent variances or unusual circumstances that occur during cardiopulmonary bypass. We hold a monthly case conference where we discuss all cases from which we can learn something–interesting cases and cases during which there was a departure from protocol.
The purpose of this paper is to discuss the development of a case conference and to outline the format and benefits of such an Error Cause Removal program.
Portable Bypass for the Procurement of Organs Used in Heart and Lung Transplants
Authors: Jones P.E. 
Published: August 2023

In July 1985, a method of organ procurement was devised using a portable cardiopulmonary bypass machine. Up to July 1985 all donors were transferred to Harefield Hospital for organ removal. Only 7 were performed by this method. Upon the introduction of the portable device, 25 more organs were transplanted, a significant increase in organ availability. To date, 114 organ procurements have been performed not only in Great Britain and Northern Ireland, but also in Europe with the longest ischemic time being 4 hours and 45 minutes.
The following is a detailed description of what was used to develop the portable machine. We utilized a bubble oxygenator cardiotomy reservoir, and a cooling system, which allows the user to cool down the donor to a temperature of 6 degrees opesophageal and approximately 8 degrees nasopharyngeal. It is believed that this method could help with the procurement of other organs, such as liver and kidneys, because of the total body cooling. This device has also been used on two occasions for the treatment of pulmonary embolism, where the operation was carried out at a non-cardiac hospital, and the transfer of such a patient would have led to the patient's demise.
Hydrogen intensified synthesis processes to valorise process off-gases in integrated steelworks
Authors: Matino Ismael , Dettori Stefano , Conde Amaia Sasian , Colla Valentina , Petrucciani Alice , Zaccara Antonella , Iannino Vincenzo , Mocci Claudio , Hauser Alexander , Kolb Sebastian , Karl Jürgen , Wolf-Zoellner Philipp , Haag Stéphane , Bampaou Michael , Panopoulos Kyriakos , Heracleous Eleni , Kieberger Nina , Rechberger Katharina , Róg Leokadia , Rompalski Przemysław 
Published: August 2023

Integrated steelworks off-gases are generally exploited to produce heat and electricity. However, further valorization can be achieved by using them as feedstock for the synthesis of valuable products, such as methane and methanol, with the addition of renewable hydrogen. This was the aim of the recently concluded project entitled “Intelligent and integrated upgrade of carbon sources in steel industries through hydrogen intensified synthesis processes (i3upgrade)”.
Within this project, several activities were carried out: from laboratory analyses to simulation investigations, from design, development and tests of innovative reactor concepts and of advanced process control to detailed economic analyses, business models and investigation of implementation cases.
The final developed methane production reactors are, respectively, an additively manufactured structured fixed-bed reactor and a reactor setup using wash-coated honeycomb monoliths as catalyst; both reactors reached almost full COx conversion under slightly over-stoichiometric conditions. A new multi-stage concept of methanol reactor was designed, commissioned, and extensively tested at pilot-scale; it shows very effective conversion rates near to 100% for CO and slightly lower for CO2 at one-through operation for the methanol synthesis.
Online tests proved that developed dispatch controller implements a smooth control strategy in real time with a temporal resolution of 1 min and a forecasting horizon of 2 h. Furthermore, both offline simulations and cost analyses highlighted the fundamental role of hydrogen availability and costs for the feasibility of i3upgrade solutions, and showed that the industrial implementation of the i3upgrade solutions can lead to significant environmental and economic benefits for steelworks, especially in case green electricity is available at an affordable price.
Foreign Body Reaction Mimicking Lymph Node Metastasis is Not Rare After Lung Cancer Resection
Authors: Cimenoglu Berk , Dogruyol Talha , Ozdemir Attila , Buz Mesut , Ece Dilek , Comert Sevda Sener , Demirhan Recep 
Published: August 2023

Abstract
Background Mediastinal lymphadenopathies with high 18-fluorodeoxyglucose uptake in patients previously operated on for lung cancer are alarming for recurrence and necessitate invasive diagnostic procedures. Peroperative placement of oxidized cellulose to control minor bleeding may lead to a metastasis-like image through a foreign body reaction within the dissected mediastinal lymph node field at postoperative examinations. In this study, we investigated clinicopathological features and the frequency of foreign body reaction mimicking mediastinal lymph node metastasis.
Methods Patients who underwent surgery for lung cancer between January 2016 and August 2021 and who were subsequently evaluated for mediastinal recurrence with endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) were included. Patients were grouped according to the results of EBUS-TBNA as metastasis, foreign body, and reactive. Clinicopathological features of these patients were compared and characteristics of patients in the foreign body group were scrutinized.
Results EBUS-TBNA was performed on a total of 34 patients during their postoperative follow-up due to suspicion of mediastinal recurrence. EBUS-TBNA pathological workup revealed metastasis in 18 (52.9%), foreign body reaction in 10 (29.4%) and reactive lymph nodes in 6 (17.6%) patients. Mean maximum standardized uptake value (SUVMax) for metastasis group and foreign body group were 9.39 ± 4.69 and 5.48 ± 2.54, respectively (p = 0.022). Time interval between the operation and EBUS-TBNA for the metastasis group was 23.72 ± 10.48 months, while it was 14.90 ± 12.51 months in the foreign body group (p = 0.015).
Conclusion Foreign body reaction mimicking mediastinal lymph node metastasis is not uncommon. Iatrogenic cause of mediastinal lymphadenopathy is related to earlier presentation and lower SUVMax compared with metastatic lymphadenopathy.
Olympic Weightlifting Training for Sprint Performance in Athletes: A
Systematic Review with Meta-analysis
Authors: Crenshaw Kristen , Zeppieri Giorgio , Hung Cheng-Ju , Schmitfranz Tania , McCall Patti , Castellini Greta , Gianola Silvia , Pozzi Federico 
Published: August 2023

AbstractThis systematic review and meta-analysis aimed to determine whether Olympic
weightlifting (OW) exercises would improve sprint performance when compared to a
control intervention, (no training, standard sport-specific training,
traditional resistance training, or plyometric training). Medline, Web of
Science, SportDiscus, CINAHL, and Biological Science from inception to September
2022 was searched. Two authors independently selected the included studies,
extracted data, and appraised the risk of bias. Certainty of the evidence was
assessed using the Grading of Recommendations Assessment, Development, and
Evaluation methodology. The primary meta-analysis combined the results of the
sprint performance over the full length of each sprint test. The secondary
meta-analyses combined the results of the sprint performance at 5, 10, and
20 m distance to capture information about the acceleration phase of the
sprint tests. Eight studies with 206 athletes (female n=10, age range:
18.9–24.2 years) were identified. Sprint performance did not differ
significantly comparing OW to the control intervention, nor at the full length
(standardized mean difference=–0.07, 95%
CI=–0.47 to 0.34, p=0.75,
I2=46%) or during the acceleration phase
(p≥0.26) of the sprint test. OW training does not improve sprint
performance to a greater extent than comparator interventions.
Synthesis and Cytotoxic Evaluation of 2-Aryl-7,8-dihydroquinolin-6(5H)-ones
Authors: Blé González Ever A. , Martínez Roberto , Bautista Diego Díaz , Chávez Santos Rosa María , Ramírez Apán María Teresa , Vilchis Reyes Miguel A. 
Published: August 2023

AbstractHerein we present a facile four-step synthetic method for the synthesis of novel 2-aryl-substituted 7,8-dihydroquinolin-6(5H)-ones as cytotoxic agents. The key step was the use of Mannich salts derived from acetophenones as a Michael acceptor in the reaction with cyclohexane-1,4-dione monoethylene acetal to give 1,5-dicarbonyl compounds that were treated with ammonium acetate to give the 7,8-dihydroquinolin-6(5H)-ones. The cytotoxic activity of the synthesized compounds was evaluated against seven cell lines. The observed data showed good selectivity for chronic myeloid leukemia line K-562. The synthetic route was simple and applicable to various functional group containing substrates. These types of compounds may be utilized as lead compounds in cancer research and drug discovery.
Regional Differences in Education: Can We Bridge that Gap with Simulation-Based Training?
Authors: Kesselman Andrew , Fornazari Vinicius Adami Vayego , Winokur Ronald S. 
Published: August 2023

AbstractInterventional radiology (IR) training is not uniform throughout the world with clear limitations to education, training, and procedural exposure based on regions within different countries and the world. Varying technical exposure can lead to limitations in technical and therapeutic opportunities for patients. Since hands-on exposure to specific procedural skills may not occur in some locations, high fidelity endovascular simulation training can provide an opportunity for technical skills to be learned with an effort to increase patient exposure to care as well as improve technical procedural skill learning.
Reconstruction Of Extensor Apparatus Of Knee By Gracilis
Authors: Sinha Dr. J.K. , Mangal Dr. K.K. 
Published: August 2023

AbstractMarginal excision, wide excision with radieal resection, hip disarticulation and hemipelvectomy are the operative modalities in vogue for the surgical management of lower extremity sarcomas. Leiomyosarcoma of lower one third of thigh is treated by wide excision and resultant defect is filled by gracilis transposition technique.
Peripheral Nerve Injuries of The Upper Extremity - Result of Late Repair
Authors: Chowdhury Dr. Siti Roy , Mukherjee Dr. A. 
Published: August 2023

AbstractOne hundred different types of peripheral nerve injuries of the upper extremity in eighty patients is the subject of study. The results of late repair between 3 months and 1 year and functional recovery thereof has been studied, both clinically and electrophysiologically. Better results are observed in children and teenagers as compared to adults. Clinical evidence of recovery is a better guide than the electrophysiological findings.
Synthesis of Ni2+–Al3+–LDHs with flower-like morphology assembled from an ultrathin platelets structure: Phenomenon of enhanced photocatalytic performance
Authors: Dang Rui , Ren Mengjiao , Zhao Huiming , Guo Wei , Ma Xiang-Rong , Kang Yu-Hong , Gao Yong , Bi Shiqing , Gao Wenwen , Hao Hua-Rui , Bai Rui , Zhang Zhi-Fang , Ma Ya-Jun 
Published: August 2023

This study was initiated to explore a method for producing higher photocatalytic performance in layered double hydroxides (LDHs) through the preparation of ultrathin nanosheets, which would generate higher surface area (SA). Herein, a method is detailed for fabricating Ni2+-Al3+-LDHs with flower-like morphology assembled from an ultrathin nanosheet (Ni2+-Al3+-LDHs-U) employing a low temperature-reflux method together with a surfactant. The resulting products’ structures, morphologies, porous properties, and bandgaps were investigated using a series of characterization techniques, which confirmed the formation of Ni2+-Al3+-LDHs-U with an ultrathin nanosheet structure (4–8 nm) and large SA (151 m2/g), which were nearly three times greater than the Ni2+-Al3+-LDHs comprising a thick nanosheet structure (50 nm, Ni2+-Al3+-LDHs-T). In addition, the bandgaps of these new Ni2+-Al3+-LDHs-U materials were 5.11 electron volts lower than the Ni2+-Al3+-LDHs-T material (5.26 eV). These flower-like morphology assembled from an ultrathin nanosheet exhibited a greatly enhanced light response that utterly decomposed methyl orange and Rhodamine B in water, which represented far better photodegradation under similar conditions compared to the thicker Ni2+-Al3+-LDHs-T and thicker Ni2+-Fe3+-LDHs-T. The increased photoreaction efficiency was explained by higher SA and catalytically active sites of the experimental product.
Fast vs slow physical aging of a glass forming liquid
Authors: Richert Ranko , Gabriel Jan P. 
Published: August 2023

Using electric fields to initiate the process of physical aging has facilitated measurements of structural recovery dynamics on the time scale of milliseconds. This, however, complicates the interesting comparison with aging processes due to a temperature jump, as these are significantly slower. This study takes a step toward comparing the results of field and temperature perturbations by providing data on field-induced structural recovery of vinyl ethylene carbonate at two different time scales: 1.0 ms at 181 K and 33 s at 169 K, i.e., 4.5 decades apart. It is found that structural recovery is a factor of two slower than structural relaxation in equilibrium, with the latter determined via dielectric relaxation in the limit of linear response. The relation between recovery and relaxation dynamics remains temperature invariant across the present experimental range.
对既存并列项的觉察与选择
Authors: Jia Qi 
Published: August 2023

摘要
摘要 本文采用会话分析的研究方法，根据汉语自然会话中“反正”引导的话语出现的序列环境和话轮设计方式，证明“反正”作为一种“表明对既存并列项的察觉和选择”的装置（device）在言谈互动中被广泛使用，其基本功能是，交际者在察觉到前文中显性或者隐性地存在着源自不同交际者话语的两个或数个并列项后，通过“反正”引导的话语表明要在其中做出选择的态度。在此基础上，本文还论证了以往研究中提到的“反正”一语所具有的“对不同意见的坚持”“表示让步”“态度指示”“回归话题”和“总结”等功能都是由上述功能衍生而来的。最后，本文明确了“反正”作为互动行为资源，具有“暗示对比”和“实现对话题的控制”等功能。
From vocal prosody to movement prosody, from HRI to understanding
humans
Authors: Scales Philip , Aubergé Véronique , Aycard Olivier 
Published: August 2023

Abstract
Human–Human and Human–Robot Interaction are known to be
influenced by a variety of modalities and parameters. Nevertheless, it remains a
challenge to anticipate how a given mobile robot’s navigation and appearance
will impact how it is perceived by humans. Drawing a parallel with vocal
prosody, we introduce the notion of movement prosody, which encompasses
spatio-temporal and appearance dimensions which are involved in a person’s
perceptual experience of interacting with a mobile robot. We design a novel
robot motion corpus, encompassing variables related to the kinematics, gaze, and
appearance of the robot, which we hypothesize are involved in movement prosody.
Initial results of three perception experiments suggest that these variables
have significant influences on participants’ perceptions of robot socio-affects
and physical attributes.