bluuebunny/crossref_metadata_2025_split huggingface dataset:
Vocabulary skills of bilingual children: The evidence for context‐dependent performance
Authors: Gómez Franco Ligia E. , Vasilyeva Marina 
Published: May 2023

AbstractMost bilingual children often display greater proficiency and preference for one of their two languages. Researchers refer to this asymmetry as language dominance. However, despite being possible to determine the overall language dominance in bilinguals, there may be substantial flexibility in their language use. In particular, the relative ease of using each language may depend on the sociolinguistic context and the language of the interlocutor which may affect the ease of accessing words in a given language. In the present work, we investigate whether and how the sociolinguistic context in an International English medium school influences bilingual children's vocabulary production. Specifically, we examine whether bilingual first‐grade children's expressive vocabulary skills vary as a function of the linguistic context (Home/School) and the language (English/Spanish) of their conversational partner. Results showed that contextual factors interacted with child's language performance. The participants' ability to name objects in Spanish was affected by the conversational partner's language, and their ability to name Home‐context words varied by language. The findings of this investigation highlight the importance of considering sociolinguistic factors when evaluating bilingual children's language skills.
Student interest in mathematics homework: Do peer interest and homework approaches matter?
Authors: Xu Jianzhong 
Published: May 2023

AbstractThe current investigation examined models of homework interest according to the data from middle school students in China. Homework interest was positively related to homework favorability, feedback quality, deep approach, monitoring motivation, peer interest, self‐concept, teacher control, and family homework help. Additionally, homework interest was negatively associated with the surface approach. At the class level, homework interest was related positively to feedback quality, yet negatively to parent education. Thus, the current study extended prior research on homework, by indicating that student interest in homework was further associated with peer interest and homework approaches. Implications for further investigation and practice are discussed based on these findings.
Apocynin alleviates weight gain and obesity‐induced adipose tissue inflammation in high‐fat diet‐fed C57BL/6 mice
Authors: Park Yea‐Jin , Gil Tae‐Young , Jin Bo‐Ram , Cha Yun‐Yeop , An Hyo‐Jin 
Published: May 2023

AbstractObesity involves chronic low‐grade inflammation within adipose tissue. Apocynin (APO) is a therapeutic agent for the treatment of inflammatory diseases. Therefore, the present study aimed to investigate whether APO can reduce weight gain and obesity‐induced adipose tissue inflammation. C57BL/6 mice were administered APO or orlistat (Orli) as a positive control with a high‐fat diet (HFD) for 12 weeks. Lipopolysaccharide‐stimulated 3T3‐L1 adipocytes were used for the in vitro study. Our results showed a significantly lower white adipose tissue (WAT) mass index in 10 mg/kg APO‐treated mice than in 20 mg/kg Orli‐treated mice. Moreover, the protein expression of adipose triglyceride lipase, fatty acid synthase, sterol regulatory element‐binding transcription factor 1, and peroxisome proliferator‐activated receptor γ was reversed in the WAT of 10 mg/kg APO‐treated mice. Furthermore, APO reduced the expression of the macrophage marker F4/80, decreased the mRNA levels of tumor necrosis factor‐α and monocyte chemoattractant protein‐1, and increased the mRNA levels of interleukin‐10 in WAT. APO decreased the phosphorylation of c‐Jun N‐terminal kinase, extracellular signal‐regulated kinase, and p65 in vivo and in vitro. Notably, APO had a stronger effect on the amelioration of adipose tissue inflammation than Orli did. Our findings lay the foundation for research on the use of APO as an agent to ameliorate weight gain and obesity‐induced inflammatory diseases.
Glycyrrhizae Radix et Rhizoma: The popular occurrence of herbal medicine applied in classical prescriptions
Authors: He Luying , Kang Qianming , Zhang Yang , Chen Man , Wang Zefei , Wu Yonghui , Gao Hetong , Zhong Zhangfeng , Tan Wen 
Published: May 2023

AbstractGlycyrrhizae Radix et Rhizoma is a well‐known herbal medicine with a wide range of pharmacological functions that has been used throughout Chinese history. This review presents a comprehensive introduction to this herb and its classical prescriptions. The article discusses the resources and distribution of species, methods of authentication and determination chemical composition, quality control of the original plants and herbal medicines, dosages use, common classical prescriptions, indications, and relevant mechanisms of the active content. Pharmacokinetic parameters, toxicity tests, clinical trials, and patent applications are discussed. The review will provide a good starting point for the research and development of classical prescriptions to develop herbal medicines for clinical use.
Molecular mechanisms underlying the potential neuroprotective effects of Trifolium pratense and its phytoestrogen‐isoflavones in neurodegenerative disorders
Authors: Al‐Shami Ahmed S. , Essawy Amina E. , Elkader Heba‐Tallah Abd Elrahim Abd 
Published: May 2023

AbstractNeurodegenerative disorders are heterogeneous, debilitating, and incurable groups of brain disorders that have common features including progressive degeneration of the structure and function of the nervous system. Phytoestogenic‐isoflavones have been identified as active compounds that can modulate different molecular signaling pathways related to the nervous system. The main aim is to shed the light on the molecular mechanisms followed by phytoestrogen‐isoflavones profound in the Trifolium pratense and discuss the latest pharmacological findings in the treatment of neurodegenerative disorders. Data were collected using different databases. The search terms used included “Phytoestrogens,” “Isoflavones,” “neurodegenerative disorders,” “Neuronal plasticity,” etc., and combinations of these keywords. As a result, this review article mainly demonstrates the potential neuroprotective properties of phystoestrogen‐isoflavones present in the Trifolium pratense (Red clover), particularly in neurodegenerative disorders. Phytochemical studies have shown that Trifolium pratense mainly includes more than 30 isoflavone compounds. Among them, phytoestrogen‐isoflavones, such as biochanin A, daidzein, formononetin, genistein (Gen), etc.,are characterized by potent neuroprotective properties against different neurodegenerative disorders. There are preclinical and clinical scientific evidence on their mechanisms of action involve molecular interaction with estrogenic receptors, anti‐inflammatory, anti‐oxidative, antiapoptotic, autophagic inducing, and so on. phytoestrogen‐isoflavones are the major bioactive components in the Trifolium pratense that exhibit therapeutic efficacy in the case of neurodegenerative disorders. This review provides detailed molecular mechanisms targeted by phytoestrogen‐isoflavones and experimental key findings for the clinical use of prescriptions containing Trifolium pratense‐derived isoflavones for the treatment of neurodegenerative disorders.
Robot‐assisted nipple‐sparing mastectomy and immediate breast reconstruction with gel implant and latissimus dorsi muscle flap: Our initial experience
Authors: Chen Kuo , Zhang Jin , Beeraka Narasimha M. , Song Dajiang , Sinelnikov Mikhail Y. , Lu Pengwei 
Published: May 2023

AbstractBackgroundThis study reports the preliminary results of da Vinci robot XI robot‐assisted nipple‐sparing mastectomy immediate breast reconstruction (R‐NSMIBR) with gel implant and latissimus dorsi muscle flap.MethodsA total of 15 patients who underwent R‐NSMIBR with gel implant and latissimus dorsi muscle flap surgery for breast cancer between September 2022 and November 2022 were evaluated.ResultsMean total operative time for R‐NSMIBR was 361.9 ± 77.0 min. As the learning curve increased, the robot arm docking time decreased rapidly from the initial 25–10 min. Average total blood loss was 27.8 ± 10.7 mL and posterior surgical margin positivity rate was 0%. Perioperative complications and local recurrences or deaths were not observed at a mean follow‐up of 3 ± 1 month 15 patients were satisfied with postoperative aesthetic results.ConclusionsR‐NSMIBR with a gel implant and latissimus dorsi muscle flap could be a new therapeutic option for breast reconstruction.
On bounded realness for ℋ∞ control design in discrete‐time descriptor systems
Authors: Park Chan‐eun , Park In Seok , Kwon Nam Kyu , Park PooGyeon 
Published: May 2023

AbstractThis article suggests a new necessary and sufficient condition of bounded real lemma (BRL) for discrete‐time descriptor systems (DTDSs). First, a Lyapunov function for DTDSs is designed by using a positive definite matrix whose the dimension equals to the rank of a singular matrix in DTDSs, whereas the existing work in the literature has considered the dimension which equals to the length of the state. By considering the zero constraint which comes from the singular matrix in DTDSs, two slack variables are introduced into the difference of Lyapunov function. Then, a set of linear matrix inequalities (LMIs) is provided to ensure the necessary and sufficient condition of the BRL for DTDSs. Next, an inversion formula is given to apply the proposed BRL to a stabilization problem of DTDSs. Based on the inversion formula, the BRL for the closed‐loop system with state‐feedback control is obtained in terms of non‐convex conditions. Therefore, a sufficient condition of the non‐convex conditions is provided in terms of LMIs. Three numerical examples show the effectiveness of the proposed approaches.
Environmental change, strategic entrepreneurial action, and success: Introduction to a special issue on an important, neglected topic
Authors: Davidsson Per , Recker Jan , Chalmers Dominic , Carter Sara 
Published: May 2023

AbstractResearch SummaryThe two premises that underpin this SEJ Special Issue on Environmental Change, Strategic Entrepreneurial Action, and Success are that all environmental changes provide positive potentials for some ventures, and that this has been under‐emphasized in past theory and research. After stating these premises and illustrating how present research treats the environment, we proceed to explain how the five articles selected for the special issue advance our thinking in this domain. We then broaden our discussion to how future entrepreneurship research can make further progress by studying interaction among environmental changes as well as their links to entrepreneurial agents, contexts (sectoral, spatial, organizational, etc.) and the entrepreneurial artifact (emerging venture). Throughout, the focus is on the enabling rather than constraining role of environmental changes.Managerial SummaryThe COVID‐19 pandemic, the digital revolution, and the sustainability transition forced by climate change demonstrate significant business impact of environmental changes, including potentials for new business initiatives. This editorial and the five vanguard articles included in this SEJ Special Issue on Environmental Change, Strategic Entrepreneurial Action, and Success outline how future research can develop better theory and evidence on this important topic. The articles address matters ranging from how COVID‐19 facilitated some technology firms' recruiting and reignited media firms' dormant initiatives to how environmental degradations sparked entrepreneurial ecosystem development in Kenya, how the level of environmental dynamism at a venture's birth impact its current ability to benefit from change, and the consequences of passing on potentials provided by environmental change.
Boosting the Methanol Oxidation Reaction Activity of Pt–Ru Clusters via Resonance Energy Transfer
Authors: Liang Jiahui , Cheng Heyun , Zhao Bolin , Hu Qiong , Xing Zihao , Zhang Yuwei , Niu Li 
Published: May 2023

AbstractThe sluggish kinetics of the methanol oxidation reaction (MOR) with PtRu electrocatalyst severely hinder the commercialization of direct methanol fuel cells (DMFCs). The electronic structure of Pt is of significant importance for its catalytic activity. Herein, it is reported that low‐cost fluorescent carbon dots (CDs) can regulate the behavior of the D‐band center of Pt in PtRu clusters through resonance energy transfer (RET), resulting in a significant increase in the catalytic activity of the catalyst participating in methanol electrooxidation. For the first time, the bifunction of RET is used to provide unique strategy for fabrication of PtRu electrocatalysts, not only tunes the electronic structure of metals, but also provides an important role in anchoring metal clusters. Density functional theory calculations further prove that charge transfer between CDs and Pt promotes the dehydrogenation of methanol on PtRu catalysts and reduces the free energy barrier of the reaction associated with the oxidation of CO* to CO2. This helps to improve the catalytic activity of the systems participating in MOR. The performance of the best sample is 2.76 times higher than that of commercial PtRu/C (213.0 vs 76.99 ). The fabricated system can be potentially used for the efficient fabrication of DMFCs.
Accelerating Industrial‐Level NO3− Electroreduction to Ammonia on Cu Grain Boundary Sites via Heteroatom Doping Strategy
Authors: Wang Yan , Xia Shuai , Cai Rui , Zhang Jianfang , Wang Jiarui , Yu Cuiping , Cui Jiewu , Zhang Yong , Wu Jingjie , Yang Shize , Tan Hark Hoe , Wu Yucheng 
Published: May 2023

AbstractAlthough the electrocatalytic nitrate reduction reaction (NO3−RR) is an attractive NH3 synthesis route, it suffers from low yield due to the lack of efficient catalysts. Here, this work reports a novel grain boundary (GB)‐rich Sn‐Cu catalyst, derived from in situ electroreduction of Sn‐doped CuO nanoflower, for effectively electrochemical converting NO3− to NH3. The optimized Sn1%‐Cu electrode achieves a high NH3 yield rate of 1.98 mmol h−1 cm−2 with an industrial‐level current density of −425 mA cm−2 at −0.55 V versus a reversible hydrogen electrode (RHE) and a maximum Faradaic efficiency of 98.2% at −0.51 V versus RHE, outperforming the pure Cu electrode. In situ Raman and attenuated total reflection Fourier transform infrared spectroscopies reveal the reaction pathway of NO3−RR to NH3 by monitoring the adsorption property of reaction intermediates. Density functional theory calculations clarify that the high‐density GB active sites and the competitive hydrogen evolution reaction (HER) suppression induced by Sn doping synergistically promote highly active and selective NH3 synthesis from NO3−RR. This work paves an avenue for efficient NH3 synthesis over Cu catalyst by in situ reconstruction of GB sites with heteroatom doping.
Photo‐Rechargeable Li‐Ion Batteries using TiS2 Cathode
Authors: Kumar Amar , Hammad Raheel , Pahuja Mansi , Arenal Raul , Ghosh Kaushik , Ghosh Soumya , Narayanan Tharangattu N. 
Published: May 2023

AbstractPhoto‐rechargeable (solar) battery can be considered as an energy harvesting cum storage system, where it can charge the conventional metal‐ion battery using light instead of electricity, without having other parasitic reactions. Here a two‐electrode lithium‐ion solar battery with multifaceted TiS2–TiO2 hybrid sheets as cathode. The choice of TiS2–TiO2 electrode ensures the formation of a type II semiconductor heterostructure while the lateral heterostructure geometry ensures high mass/charge transfer and light interactions with the electrode. TiS2 has a higher lithium binding energy (1.6 eV) than TiO2 (1.03 eV), ensuring the possibilities of higher amount of Li‐ion insertion to TiS2 and hence the maximum recovery with the photocharging, as further confirmed by the experiments. Apart from the demonstration of solar solid‐state batteries, the charging of lithium‐ion full cell with light indicates the formation of lithium intercalated graphite compounds, ensuring the charging of the battery without any other parasitic reactions at the electrolyte or electrode‐electrolyte interfaces. Possible mechanisms proposed here for the charging and discharging processes of solar batteries, based on the experimental and theoretical results, indicate the potential of such systems in the forthcoming era of renewable energies.
DNA sequences as types: A discussion paper from the Special‐purpose Committee established at the XIX International Botanical Congress in Shenzhen, China
Authors: Thiele Kevin R. , Applequist Wendy L. , Renner Susanne S. , May Tom W. , Dönmez Ali A. , Groom Quentin , Lehtonen Samuli , Maggs Christine A. , Malécot Valéry , Yoon Hwan Su 
Published: May 2023

AbstractA special‐purpose Committee on DNA Sequences as Types was established at the XIX International Botanical Congress (IBC) in Shenzhen, China, in 2017, with a mandate to report to the XX IBC in Madrid in 2024 with recommendations on a preferred course of action with respect to potential amendments of the International Code of Nomenclature for algae, fungi, and plants to allow DNA sequences as types. This is the first in an expected series of papers from the Special‐purpose Committee on this issue. We set out the background to the establishment of the Committee, explore key issues around typification that are pertinent to the question of DNA sequences as types, enumerate pros and cons of allowing DNA sequences as types, and foreshadow options for future discussion and potential recommendations.
[(SIPr)Ag(CF2H)]: A Shelf‐Stable, Versatile Difluoromethylation Reagent
Authors: Zhao Haiwei , Gu Yang , Shen Qilong 
Published: May 2023

AbstractDue to its unique physical and electrophilic properties, the difluoromethyl group (−CF2H) has been playing an irreplaceable role in the field of pharmaceutical and agrochemical industry. Methods that could efficiently incorporate the difluoromethyl group into the target molecules are increasing in the recent years. Developing a stable and efficient difluoromethylating reagent is thus highly attractive. In this review, we describe the development of a nucleophilic difluoromethylation reagent [(SIPr)Ag(CF2H)], including its elemental reaction, difluoromethylation reaction with different types of electrophiles, and its application in the synthesis of a nucleophilic and an electrophilic difluoromethylthiolating reagent.
METTL14 represses osteoclast formation to ameliorate osteoporosis via enhancing GPX4 mRNA stability
Authors: Deng Mingsi , Luo Jia , Cao Heng , Li Yong , Chen Liangjian , Liu Gengyan 
Published: May 2023

AbstractExcessive bone resorption by osteoclasts results in the development of multiple bone disorders including osteoporosis. This study aimed to explore the biological function of methyltransferase‐like14 (METTL14) in osteoclast formation, as well as its related mechanisms. Expression levels of METTL14, GPX4 and osteoclast‐related proteins TRAP, NFATc1, c‐Fos were detected by qRT‐PCR and Western blotting. The osteoporosis model was established in mice by bilateral ovariectomy (OVX). Bone histomorphology was determined by micro‐CT and H&E staining. NFATc1 expression in bone tissues was determined by immunohistochemical staining. Proliferation of primary bone marrow macrophages cells (BMMs) was assessed by MTT assay. Osteoclast formation was observed by TRAP staining. The regulatory mechanism was evaluated by RNA methylation quantification assay, MeRIP‐qPCR, dual luciferase reporter assay, and RIP, respectively. METTL14 was down‐regulated in the serum samples of postmenopausal osteoporotic women, which was positively associated with bone mineral density (BMD). Osteoclast formation was promoted in OVX‐treated METTL14+/− mice as compared with wild‐type littermates. Conversely, METTL14 overexpression repressed RANKL‐induced osteoclast differentiation of BMMs. Mechanistically, METTL14‐mediated m6A modification post‐transcriptionally stabilized glutathione peroxidase 4 (GPX4), with the assistance of Hu‐Antigen R (HuR). Finally, GPX4 depletion‐mediated osteoclast formation in BMMs could be counteracted by METTL14 or HuR overexpression. Collectively, METTL14 inhibits osteoclastogenesis and bone resorption via enhancing GPX4 stability through an m6A‐HuR dependent mechanism. Therefore, targeting METTL14 might be a novel promising treatment strategy for osteoporosis.
Isolation and identification of Mannheimia haemolytica and Pasteurella multocida from symptomatic and asymptomatic sheep and their antibiotic susceptibility patterns in three selected districts of north Gondar zone, Gondar Ethiopia
Authors: Abate Fentahun Mitku , Fentie Kassa Tsegaw 
Published: May 2023

AbstractBackgroundSmall ruminants are the most numerous of man's domestic livestock. Although sheep represent a great resource for Ethiopia, the net rate of productivity per animal is very low due to many factors including respiratory disorders.ObjectivesThe objectives of this work were to isolate and identify M. haemolytica and P. multocida as well as to assess the antibiotic susceptibility patterns of these isolates. Nasal swab samples were collected aseptically by using 70% alcohol as a disinfectant.MethodsA cross‐sectional study was conducted in three selected districts of the north Gondar zone, Ethiopia.ResultsFrom 148 samples collected in 94 (63.5%) asymptomatic and 54 (35.5%) symptomatic sheep, a total of 23 were isolated successfully based on cultural, staining, and biochemical characteristics. Of these isolates, 18 (78.3%) and 5 (21.7%) were M. haeimolytica and P. multocida, respectively. Compared with the total animals examined, the proportion of M. haeimolytica and P. multocida were 12.16 % (n = 18) and 3.38% (n = 5), respectively. All of the isolates were subjected to a panel of 8 antibiotic discs for sensitivity testing. Of the tested antibiotics, chloramphenicol (100%), gentamicin, and tetracycline (82.6%) each and co‐trimoxazole (60.8%) were found to be the most effective drugs whereas, both species were completely resistant to vancomycin and showed a very low degree of susceptibility for the rest drugs.ConclusionsIn conclusion, M. haemolytica was found to be the predominant isolate in all host‐related factors and most of the antibiotics were not fully effective against the isolates. Hence, treatment and/or vaccination of ovine pneumonic pasteurellosis should be emphasised to M. haeimolytica using the most effective drugs along with appropriate herd management practices.
Why Sustainability?
Authors: Fischer Manuel , Foord Daniel , Frecè Jan , Hillebrand Kirsten , Kissling-Näf Ingrid , Meili Rahel , Peskova Marie , Risi David , Schmidpeter René , Stucki Tobias 
Published: May 2023

AbstractOver the past 30 years, sustainable development has become the central term worldwide in discussions about the future development of humanity and planet Earth. The struggle to define what sustainable development really means and how to achieve it, has become a central theme of national and international politics, science, and increasingly also of business and civil society. But why has the concept of sustainable development become central to many disparate debates across the world? In this chapter we discuss the biggest social and environmental challenges facing the world today and the basic processes, causes, and effects of climate change.