bluuebunny/crossref_metadata_2025_split huggingface dataset:
CẬP NHẬT ĐIỀU TRỊ VIÊM GAN VIRUS C 2023
Authors: Trần Xuân Chương 
Published: July 2023

Bệnh viêm gan virus C có ảnh hưởng đáng kể đến tỷ lệ mắc bệnh và tử vong trên toàn thế giới vì đây là nguyên nhân gây xơ gan, ung thư biểu mô tế bào gan, ghép gan và tử vong liên quan đến gan. Ước tính tỷ lệ nhiễm virus viêm gan C (HCV) toàn cầu hiện nay là 1%, tương ứng với 71 triệu người nhiễm bệnh. Ở Việt Nam, nghiên cứu của Tổ chức Y tế Thế giới (2019) ước tính có khoảng hơn 1 triệu người nhiễm HCV.
Các chiến lược sàng lọc hiện nay chủ yếu nhằm vào những người có nguy cơ cao nhiễm HCV: người tiêm chích ma túy, có người thân trong gia đình nhiễm HCV, bệnh nhân được lọc máu chu kỳ... Các loại thuốc kháng virus trực tiếp (DAA) đều chứng tỏ có hiệu quả cao, an toàn và có thể được sử dụng cho tất cả bệnh nhân viêm gan C. Thời gian điều trị ngắn, thuốc dung nạp tốt và ngay cả những bệnh nhân bị xơ gan mất bù hoặc các bệnh nền cũng có thể được điều trị. Tổ chức Y tế Thế giới (WHO) đã phê duyệt Chiến lược Toàn cầu nhằm loại trừ nhiễm HCV vào năm 2030. Bài tổng quan này trình bày những khuyến cáo mới nhất của WHO và AASLD về các chiến lược chẩn đoán, điều trị và điều trị viêm gan C ở các đối tượng đặc biệt.
ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ KẾT QUẢ ĐIỀU TRỊ BỆNH UỐN VÁN TẠI BỆNH VIỆN ĐÀ NẴNG
Authors: Trương Thị Hoa 
Published: July 2023

Đặt vấn đề: Uốn ván là một bệnh nhiễm trùng cấp tính nặng, có khả năng gây tử vong cao do độc tố của vi khuẩn uốn ván (Clostridium tetani) gây ra đặc trưng bởi các cơn co giật trên nền tăng trương lực cơ.
Mục tiêu: Mô tả các đặc điểm lâm sàng, cận lâm sàng và đánh giá kết quả điều trị bệnh uốn ván tại Bệnh viện Đà Nẵng từ tháng 01/2021 đến tháng 5/2023.
Đối tượng và phương pháp: 50 bệnh nhân ≥ 15 tuổi được chẩn đoán uốn ván theo tiêu chuẩn Bộ Y tế, được điều trị tại Khoa Y học nhiệt đới, Bệnh viện Đà Nẵng trong thời gian từ ngày 01/01/2021 đến ngày 31/5/2023. Mô tả cắt ngang kết hợp hồi cứu.
Kết quả và kết luận: Nam giới chiếm 72%, nhóm tuổi ≥ 60 tuổi chiếm 50%; vị trí vết thương ngõ vào chủ yếu hai chi dưới 64%. Thời gian ủ bệnh trung bình 10,2 ± 7,1 ngày. Sốt vào ngày đầu nhập viện 22%; cứng hàm 98%; co cứng cơ cục bộ 24%; co cứng cơ toàn thân 76%; nuốt khó 90%; khó thở 62%; co giật 46%; nhịp tim ≥ 120 lần/phút 38%; vã mồ hôi 48%; bí đại hoặc tiểu tiện 32%; thân nhiệt ≥ 41oC chiếm 18%, mở khí quản: 52%. Tăng creatinin kinase máu 86%. Biến chứng viêm phổi hay gặp nhất 40%. Tỷ lệ tử vong 18%.
Kết luận: Uốn ván thường gặp ở nam giới, lớn tuổi. Đa số có triệu chứng cứng hàm, co cứng cơ, nuốt khó. Tỷ lệ bệnh nhân uốn ván nặng cần mở khí quản cao.
PENGARUH MEKANISME GOOD CORPORATE GOVERNANCE TERHADAP PRAKTIK MANAJEMEN LABA
Authors: Wahyuwidi Syafira Fitri , Lusmeida Herlina 
Published: July 2023

Penelitian ini bertujuan untuk menganalisis dan memberikan bukti secara empiris mengenai pengaruh antara mekanisme good corporate governance yang diproksikan dengan proporsi dewan komisaris independen, jumlah dewan direksi, kepemilikan manajerial, kepemilikan institusional dan kualitas audit terhadap praktik manajemen laba. Penelitian ini menggunakan 39 sampel perusahaan manufaktur sektor industri barang konsumsi yang terdaftar di Bursa Efek Indonesia selama periode 2016 sampai dengan 2019 yang dipilih dengan menggunakan purposive sampling method, sehingga didapatkan 140 data observasi. Pengolahan data dilakukan dengan menggunakan analisis regresi berganda. Hasil penelitian ini mengindikasikan bahwa proporsi dewan komisaris independen, kepemilikan manajerial, dan kualitas audit berpengaruh secara negatif dan signifikan terhadap manajemen laba. Sedangkan kepemilikan institusional berpengaruh secara positif dan signifikan terhadap manajemen laba, dan jumlah dewan direksi tidak berpengaruh secara signifikan terhadap manajemen laba.
Kata kunci: Discretionary accruals, good corporate governance, manajemen laba.
LIKUIDITAS, SOLVABILITAS, DAN PROFITABILITAS PERUSAHAAN KONSTRUKSI
Authors: Sihaloho Cristy Hulda Nauli , Tamauka Asih Christi Pratiwi , Kasingku Frisky Jeremy 
Published: July 2023

Penelitian ini bertujuan untuk menguji pengaruh likuiditas dan solvabilitas terhadap profitabilitas perusahaan konstruksi pada tahun 2016-2018. Data yang digunakan dalam penelitian ini berupa data sekunder. Pengambilan sampel ditentukan berdasarkan metode purposive sampling. Metode penelitian yang digunakan adalah kuantitatif. Lebih lanjut lagi, untuk menjawab masalah penelitian, regresi sederhana dan regresi berganda digunakan. Hasil penelitian menunjukkan bahwa likuditas dan solvabilitas secara simultan berpengaruh signifikan terhadap profitabilitas yang diukur menggunakan Return on Equity.Akan tetapi, secara parsial, masing-masing variabel tidak memiliki pengaruh terhadap profitabilitas. Implikasinya, perusahaan perlu untuk meningkatkan kinerja likuiditas dan profitabilitas agar dapat meningkatkan profitabilitas perusahaan sehingga dapat memaksimalkan kesejahteraan pemilik perusahaan.
Kata kunci: Likuiditas, solvabilitas, profitabilitas
EARNINGS AND CASH FLOW IN PREDICTING FINANCIAL DISTRESS
Authors: Malumbeke Queensly , Kasingku Frisky Jeremy 
Published: July 2023

This study aimed to test the effect of earnings and cash flow to predict the probability of financial distress. This study examines seven years of financial report investigate the prediction ability of earnings and cash flows to financial distress in a longer period. This study uses manufacturing companies listed in Indonesian Stock Exchange as the sample. Earnings before taxes and operating cash flow ratio data on the 2012-2017 is used to predict financial distress. This research used causal descriptive method and data were analyzed with logistic regression models with SPSS. The results of this study show that earnings have a significant influence in predicting financial distress that occurred in manufacturing sector companies. However, cash flow was not able to predict the financial distress.
Keywords: Earnings, cash flow, financial distress
Penelitian ini bertujuan untuk menguji pengaruh laba dan arus kas untuk memprediksi probabilitas terjadinya financial distress. Penelitian ini mengkaji laporan keuangan tujuh tahun dengan menyelidiki kemampuan prediksi laba dan arus kas terhadap financial distress dalam periode yang lebih lama. Penelitian ini menggunakan perusahaan manufaktur yang terdaftar di Bursa Efek Indonesia sebagai sampel. Data laba sebelum pajak dan rasio arus kas operasi tahun 2012-2017 digunakan untuk memprediksi financial distress. Penelitian ini menggunakan metode deskriptif kausal dan data dianalisis dengan model regresi logistik dengan bantuan SPSS. Hasil penelitian ini menunjukkan bahwa laba memiliki pengaruh yang signifikan dalam memprediksi financial distress yang terjadi pada perusahaan sektor manufaktur. Namun, arus kas tidak mampu memprediksi kesulitan keuangan.
Kata kunci: Laba, arus kas, financial distress
Parenteral Corticosteroids After Fragility Fracture Increases the Odds of a Repeat Fracture
Authors: David Justin , Benes Gregory , Dasa Vinod , Krause Peter G. , Leslie Lauren , Jones Deryk , Chapple Andrew G. 
Published: August 2023

Purpose To determine if corticosteroid use is associated with repeat fragility fractures and the trends in corticosteroid usage in this population. Methods 2,643 patients with repeat fractures were identified in the Research Action for Health Network (REACHnet). Each patient had a non-traumatic fracture diagnosis code with at least one year of medical history prior to the fracture and at least two years of follow-up time. Multivariable logistic regression was used to identify corticosteroid trends over time, predictors of a repeat fracture, and the effect of timing and type of corticosteroid on repeat fracture. Results Corticosteroid use was associated with a significantly increased risk of a second fragility fracture (Adjusted Odds Ratio, aOR = 1.39, 95% CI = 1.13-1.71). Parenteral corticosteroids were associated with significantly increased odds of re-fracture (aOR = 1.37. 95% CI = 1.08-1.74). Corticosteroid usage after initial fracture showed significantly increased odds of repeat fracture (aOR = 1.52, 95% CI = 1.20-1.91). Parenteral corticosteroid use after fracture was associated with an increased risk of re-fracture (aOR = 1.52, 95% CI 1.18-1.96).  Increased total dosage of steroids was not associated with an increase in the rate of repeat fractures. Conclusions Parenteral corticosteroid administration, especially if used after the initial fracture, was most likely to be associated with a repeat fracture. If steroids are indicated, the dosage may not alter repeat fracture risk. The method of administration or the timing may play a larger role, especially parenteral steroids after fracture. Physicians should weigh benefits and risk with parenteral corticosteroid use in fragility fracture patients.
Status Quo Pengaturan Pasal Penghinaan Presiden Sebagai Pembatas Hak Konstitusional Terkait Kebebasan Berpendapat Di Indonesia Beserta Potensi Pengaturannya Di Masa Depan: Studi Kasus Penghinaan Presiden Di Media Sosial (Kasus Ruslan Buton)
Authors: Ellandra Athallah Zahran , Faqih Muhammad , Azizi Kemal 
Published: July 2023

ABSTRAK
Tindak pidana penghinaan terhadap Presiden dan/atau Wakil Presiden merupakan bagian dari pidana penghinaan terhadap penguasa, yang diatur dalam pasal 134, 136 bis, dan pasal 137 KUHP. Namun, Putusan MK No.013-022/PUU IV/2006 dan Putusan MK No. 6/PUU-V/2007 telah membatalkan delik penghinaan yang ada. Selain KUHP dan Putusan MK, adanya pasal 217 hingga 220 serta pasal 240 dan pasal 241 RKUHP memberi makna bahwa tindak pidana penghinaan Presiden masih akan diatur di masa depan. Kasus yang menimpa Ruslan Buton merupakan contoh praktis terjadinya penghinaan terhadap Presiden di media sosial. Tujuan penelitian ini adalah untuk mengetahui perbandingan pengaturan tindak pidana penghinaan Presiden saat ini, di masa depan, dan contoh praktis di masyarakat. Metode penelitian yang digunakan adalah yuridis normatif. Hasil penelitian menunjukkan bahwa Pasal 240 dan Pasal 241 RKUHP berpotensi untuk menghambat hak atas kebebasan berpendapat, berpotensi menghalangi upaya komunikasi dan hak untuk memperoleh informasi, serta menimbulkan ketidakpastian hukum dengan adanya persamaan mengenai unsur tindak pidana antara Pasal 134, Pasal 136 bis, Pasal 137, Pasal 154 dan Pasal 155 KUHP yang telah dinyatakan batal demi hukum oleh MK.
Pelatihan dan Pengembangan Obyek Wisata Wisuka di Desa Sukoanyar, Kecamatan Wajak, Kabupaten Malang
Authors: Kholil A Yusuf , Mutiara Farah , Novitawati Retno Ayu Dewi 
Published: July 2023

Subjek dalam pengabdian ini adalah masyarakat, para pemerintah desa, pengelola wisata wisuka. Objek dalam penelitian ini adalah Strategi pengembangan yang dilakukan dalam hal pengembangan wisata di wisata wisuka. Penentuan lokasi penelitian dilakukan secara sengaja (purposive) yaitu Wisata Wisuka yang terletak di Desa Wajak, Kecamatan, Kabupaten Malang dengan pertimbangan bahwa daerah ini memiliki banyak potensi wisata yang memungkinkan untuk keperluan kegiatan pengabdian masyarakat agar dapat mengembangkan potensi wisata yang dimiliki.. Metode pengabdian masyarakat yang digunakan dalam kegiatan ini yaitu memberikan media atau sarana prasarana guna mendukung potensi Wisata Wisuka dalam pengembangannya sebagai daerah wisata.
The subjects in this service are the community, village governments, and Wisuka tourism managers. The object of this research is the development strategy carried out in terms of tourism development in Wisuka tourism. The determination of the research location was carried out purposively, namely Wisuka Tourism which is located in Wajak Village, District, Malang Regency with the consideration that this area has a lot of tourism potential that allows for community service activities so that it can develop its tourism potential. Community service methods which is used in this activity is to provide media or infrastructure to support the potential of Wisuka Tourism in its development as a tourist area.
Penanaman Konsep Manajemen Diri dalam Era Digital di Kalangan Pondok Pesantren Muhammadiyah Takerharjo
Authors: Prayogo Moh Dey 
Published: July 2023

Memahami pentingnya konsep manajemen diri sebagai modal utama untuk menghadapi masa depan bagi pelajar Pondok Pesantren Muhammdiyah di desa Takerharjo Lamongan merupakan suatu tuntutan wajib yang di berikan oleh lembaga tersebut. Keselarasan antara kemampuan akademik dengan moralitas yang baik adalah poin penting yang menjadi perhatian khusus oleh lembaga untuk menyiapkan para siswa-siswi yang akan mengarungi kehidupan yang lebih kompleks setelah mereka menamatkan pendidikan formal mereka di tingkat SLTA. Selama ini kemajuan teknologi digital yang tercermin melalui smartphone mejadi hambatan yang besar yang dapat mengganggu cita-cita dan pembalajaran para siswa yang selama ini di tempuh karena belum di pahaminya cara bijak dalam memanfaatkan kemajuan teknologi di era digital seperti sekarang ini sebagai pendukung pengembangan potensi yang ada pada setiap pelajar. Atas permasalahan tersebut penulis mendapatkan amanah untuk melakukan sosialisasi dan pemaparan sesuai dengan kemampuan penulis terkait bagaimana memanfaatkan perkembangan teknologi di era digital sebagai salah satu instrumen pengembangan diri melalui konsep manajmenen diri yang baik. Hasil yang di dapatkan dalam kegiatan tersebut yakni meningkatnya pemahaman para peserta kegiatan dalam memaknai konsep manajemen diri yang efektif di era digital, antara lain bijak dalam menggunakan smartphone sesuai dengan kebutuhan akademik dan juga sebagai alat untuk mengasah kemampuan diri baik dalam bidang soft-skill ataupun dalam bidang hard-skill.
Understanding the importance of the concept of self-management as the main capital to fight the future for students of the Muhammdiyah Islamic Boarding School in Takerharjo Lamongan village is a mandatory demand given by the institution. The harmony between academic ability and good morality is an important point of special concern by the institution to prepare students who will navigate a more complex life after they finish their formal education at the high school level. So far, the advancement of digital technology reflected through smartphones has become a big obstacle that can interfere with the ideals and learning of students who have been taken because they have not understood how to wisely utilize technological advances in the digital era like today as a support for the development of the potential that exists in every student. For this problem, the author has the mandate to conduct socialization and exposure in accordance with the author's ability related to how to utilize technological developments in the digital era as an instrument of self-development through the concept of good self-management. The results obtained in the activity were an increase in the understanding of the participants in interpreting the concept of effective self-management in the digital era, including being wise in using smartphones in accordance with academic needs and also as a tool to hone self-abilities both in the soft-skill field and in the hard-skill field
Effect of Urea Fertilizer Dosage and Under-Cob Leaf Removal on Growth and Production of Three Maize Varieties
Authors: Kaimuddin Kaimuddin , Kuruseng M.Askari , Ala Ambo 
Published: July 2023

The assimilation products produced by the leaves will be distributed to all parts of the plant that need it. The presence of leaves can help smooth assimilation, but can also be a user of assimilate products. The removal of leaves under the cob is done to streamline the process of photosynthesis that occurs in old leaves that cause moisture, it is also intended to suppress the occurrence of internal competition in assimilation, while the need to be given the right fertilizer or nutrition for the growth and production of corn which is needed, namely Nitrogen in Urea Fertilizer. This study aims to analyze the growth and production of three varieties of corn with the application of different doses of urea fertilizer and leaf shredding under the cob. The research was conducted in the form of a multifactor experiment arranged based on a Split Split Plots Design (SSP) in a Randomized Group Design (RAK) pattern consisting of the Main Plots Factor (MP), namely Maize Variety Type consisting of Agricon, BISI-10,and C7 Varieties. Sub Plots (SP) are doses of urea fertilizer of 250 kg.ha-1 and 350 kg.ha-1 respectively, and Sub Sub Plots (SSP) are the method of leaf trimming under the cob consisting of No trimming. Composting at anthesis, and Composting 1 week after anthesis. The results of the analysis showed that the Bisi-10 variety gave a better response to the dose of urea fertilization at the vegetative growth stage of corn plants and the Agricon variety gave a better response to urea fertilization and pumping time at the generative growth stage, the dose of urea fertilizer 350 kg ha-1 gave a better response to the growth and development of corn plants and corn plant production and the time of pumping the leaves under the cob at the time of pollination was more effective in increasing the quality and quantity of corn plant production.
Ser estoico y hacerse indiferente. El Principio y Fundamento de los Ejercicios Espirituales de san Ignacio de Loyola Observaciones vinculantes y disgregantes
Authors: López Eduard 
Published: July 2023

¿Es posible que la indiferencia en los Ejercicios Espirituales de san Ignacio presente alguna huella de los estoicos como Epicteto o Marco Aurelio? Este artículo analiza algunas observaciones que relacionan el ser estoico y el hacerse indiferente en dos escuelas espirituales totalmente diversas. Tras un estado de la cuestión, analizamos el Principio y Fundamento de los Ejercicios en relación a la indiferencia. Mediante algunos textos de los estoicos, comparamos el modo de comprender la vida, el fin del ser humano y su relación divino-humana. A modo de conclusión, finalizamos con una serie de líneas sobre la indiferencia para el estoicismo y la teología ignaciana.
Novel Impact Model for Mobile Learning Adoption in Higher Education
Authors: Dolawattha D. D. M. , Premadasa H. K. Salinda 
Published: July 2023

In successful mobile learning (ML) integration, factors associated with live-ware, software, and infrastructure are important. The main objective of this study is to investigate and model the influencing factors for learners and teachers at once to adopt ML in higher education. The proposed model consists of five impact factors: teacher, learner, mobile devices, ML tools, ML contents, communication technologies, and higher education institutes. Then the proposed model was implemented using a modified Moodle mobile application and evaluated using 60 teachers and 60 learners attached to the University of Kelaniya, Sri Lanka in 2021. According to the experimental research design approach, the proposed impact model was assessed as pre-test and post-test surveys using seven questionnaires. According to the Pearson correlation coefficient test, the most significant factor for learners and teachers to adopt ML is the mobile device. Learning content and communication technology were elected as the second most significant adoption factors for teachers and learners consecutively. However, higher correlation values were obtained for all factors denoting that they are greatly influenced the participant to adopt ML. The significant influencing factor of each impact factor was also investigated. In conclusion, it was recommended that featured smart devices, quality learning content, user-satisfied communication technology, academic enriched ML tools and higher education institutes with sound educational facilities are crucial for the university community to adopt ML in higher education. These findings help design academic community acceptable ML environments for higher education context.
Evaluation of the Effect of Foliar Nano Nitrogen and Zinc on Chlorophyll (SPAD) and Qualitative Traits of Green Chilli in Comparison with Urea and ZnSO4
Authors: Kanavi G. B. Jayanth , Sunil C. , Salimath Sarvajna B. , Mallikarjuna H. B. , Kadam Praveen V. , Jeevan H. R. 
Published: July 2023

The faulty and imbalanced application of fertilizers to chilli threatens the environment and affects the country's sustainable food and nutritional security. Variation in the method and quantity of N and Zn fertilizer application has a higher impact on the chilli production and quality. An experiment was carried out at AHRS, Bavikere, KSNUAHS, Shivamogga, to study the effect of foliar nano nitrogen and zinc application on green chilli's growth, yield and quality. There were eight treatments which replicated three times using the RCBD design. Treatment combinations of foliar nano nitrogen and zinc and foliar urea and ZnSO4 with different levels of RDN (75%, 100%, 125%) were tested against control (100% RDF). The results revealed that chilli quality parameters significantly varied with applying nano N and Zn compared to the control. Among the treatments, application of RDN (125%) and foliar nano N (0.4%) and Zn (0.4%) at 30 and 45 DAT registered significantly higher chlorophyll, oleoresin, ascorbic acid and TSS. T3 reported significantly superior ascorbic acid and oleoresin content to 14.94 per cent and 22.10 per cent over control.
Impacts of Clinker Storages Heat Transfer, Its Effect on Vertical Roller Cement Performances: A Case Study of Cement Grinding Operations in Nigeria
Authors: Joseph Oyepata Sunday , Baba N. Z. , Idowu E. T. , Adediran A. A. 
Published: July 2023

Operational data indicates that vertical roller cement mills (VRCM) consumed lesser energy when compared to horizontal/ball mills. A case study of a vertical roller cement mills was carried out in Nigeria which was experiencing a lower production output and a higher energy consumption. This research was to investigate reasons behind the low production output on the VRCM. A thorough analysis was carried out on the clinker storage facilities and the heat transfer across the composite cylindrical clinker silo walls (off – spec and main clinker) both silos having the same design but with different dimensions and with different application purpose. The off-spec clinker silo has a design capacity of 1,800 tons and main clinker silo a design capacity of 60, 000 tons and both silo stores hot clinker that left the kiln clinker cooler at approximate temperature of 95oC. The analytical results shows that the rate of heat transfer across the main clinker composite walls was 728 kW and the rate of heat transfer across the off-spec clinker composite walls was 217.15 kW. Numerical simulation was also carried out using ANSYS simulation package and the results obtained were in good agreement with the results obtained theoretically. The ratio of heat loss on the main clinker composite walls to off-spec clinker composite walls was 3.35:1.