bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Genetic Analysis of Potential New HEV-3 Subtype Identified on Pig Farm in Slovakia
Authors: Kočíková Božena , Pavlová Alica , Dudášová Katarína , Mandelík René , Jacková Anna 
Published: June 2023

Abstract
Hepatitis E virus (HEV) represents the causative agent of acute viral hepatitis in the world. The virus belongs to the genus Paslahepevirus, species Paslahepevirus balayani, which contains 8 different genotypes and at least 14 reference HEV-3 subtypes. Recently we have identified three isolates in a Slovakian pig farm as a new unclassified HEV-3 subtype. The aim of this study was to sequence and analyze additional regions of HEV genome for PER5 isolate, a representative isolate of potential new HEV-3 subtype. The phylogenetic analyses of 749 bp and 828 bp DNA fragments amplified from ORF1 revealed that both sequences fall outside two major clades (3abchij and 3efg) of the HEV-3 genotype as well as the other HEV-3 subtypes. The nucleotide identity with other HEV-3 subtypes indicated low values within the range 79.2–84.1 % as well. The results provide further support for the circulation of a new HEV-3 subtype in the pig farm in Slovakia.
Brain Gross Anatomy and Cerebellar Histology of the Cattle Egret (Bubulcus ibis)
Authors: Azeez Idris A. , Omirinde Jamiu O. , Chomo Jerry J. , Olopade James O. 
Published: June 2023

Abstract
The structural parts of brain are similar in all vertebrates, but they differ in their complexity and organization. The avian brain for instance, is organised differently compared to mammals, with variations existing in the relative size and location of their structures. The cattle egret (Bubulcus ibis) is a cosmopolitan avian species native to Africa. Despite their economic importance as excellent sentinels in assessing environmental pollutants, there is a dearth of information on their neuroanatomy. Hence, we here investigated their gross morphological features and morphometric parameters, and the cerebellar histology. Twelve transcardi-ally perfused juvenile cattle egrets were studied, with the body and brain weights and brain linear measurements considered. The brain weight constituted 0.46 % of the total body mass, with a strong positive correlation recorded between the body and brain weights (r = 0.9204). Morphologically, the brain was lissencephalic, with the corpus callosum absent and the olfactory bulbs rudimentary with no discernible division into the olfactory bulb, olfactory tract and olfactory lobe. We observed prominent sagittal eminence and vallecula telencephali, as well as an obvious fovea limbica on the dorsal and lateral surfaces of the cerebral hemispheres, respectively. The diencephalic structures were completely covered by telencephalon, with the pineal gland occupying the polygonal space between cerebrum, optic lobe and cerebellum. The mesencephalic tectum appeared as a large oval bilaterally bulging structure with prominent optic tracts and constituted the bulk of the midbrain. There was a dorsal extension of the fourth ventricle into the cerebellum known as the ventriculus cerebelli and the cerebellar histology presented a persistent external granular layering suggestive of a potential for adult neurogenesis. Our data has added relevant literature on the cattle egret brain and could prove useful in comparative, developmental and evolutionary avian neuroanatomy.
Growth and yield performance of three peanut cultivars on different watering intervals
Authors: Sagala Danner , Sudaryanti Meli , Prihanani  
Published: June 2023

Many peanut planting fields have limited water resources, therefore farmers must use water efficiently. A study aimed to obtain appropriate watering intervals and adaptive peanut cultivars at limited water conditions. The greenhouse study was conducted at Central Bengkulu Regency, Indonesia, from December 2019 to March 2020. Three varieties of peanut (Takar 2, Talam 1, and Kancil) and four watering intervals (1, 3, 6, and 9-day intervals) were arranged using a split-plot design and replicated three times. Results showed that the three varieties evaluated had similar agronomic performance (P≥0.05). The Takar 2 and Kancil had similar growth and yield components to the dry land adaptive variety Talam 1. It indicates that Takar 2 and Kancil cultivars are suitable for cultivation in a water-limited field. Watering every 6 days reduced peanut growth and insignificantly differed from watering every 9 days. Daily watering produced the highest growth and yield of peanut, irrespective of genotypes. Nevertheless, in areas with limited water availability, watering every 3 days was sufficient with yield reduction by about 25.55% of watering daily.
Keywords: drought, irrigation, peanut production
The influence of intraoperative sedation on memory consolidation: a single-blind randomized controlled trial
Authors: Churakov V. O. , Zaitsev A. Yu. , Vzorin G. D. , Bukinich A. M. , Dubrovin K. V. , Anokhin K. V. , Nourkova V. V. 
Published: June 2023

The objective was to evaluate the effect of propofol and dexmedetomidine sedation on the short-term memory and long-term memory consolidation.Materials and methods. 80 patients with small orthopaedic interventions under subarachnoid anesthesia were included in the randomized controlled trial. Three groups were formed depending on the drug used: group P – propofol, group D – dexmedetomidine, group 0 – control. Emotionally neutral sets of words were tapped three times to evaluate the effect of sedation on long-term memory consolidation: stage1/set 1 – immediately before sedation (RASS 0, BIS 95–100), stage 2/set 2 – 5–10 minutes after the start of sedation (RASS «–1» – «–2», BIS 70–90), stage 3/set 3 – 10 minutes after sedation was terminated and consciousness was recovered (RASS 0, BIS 90–100). In addition, the impact of sedation on the ability to hold the received information in short-term memory was conducted 5 minutes after the presentation of the words at stage 2. Reproduction and recognition testing of all words was conducted the next day after operation to evaluate the effect of medical sedation on long-term memory consolidation.Results. Propofol and dexmedetomidine provided an inhibitory effect on the ability to hold information in short-term memory compared to control group (р < 0.001 и р < 0.001, respectively). Propofol had the most effect on short-term memory and the level of its amnesic effect was associated with the cognitive function of patients (p = 0.013, R² = 0.23, β = 0.472). The HADS points were as negative predictor of the reproduction of the word set 1 in control group (p = 0.05, R² = 0.136, β = –0.368) and recognition of the word set 3 in propofol group (р = 0.029, R² = 0.176, β = –0.420). Within 24 hours after operation, reproduction and recognition of word sets 2 depended on the degree of short-term memory impairment during sedation (F(1.65) = 19.317, p < 0.001, ηp2 = 0.229 и F(1.65) = 21.638, p < 0.0031, ηp2 = 0.250, respectively). Short-term memory test acted as a positive predictor of the reproduction of word set 3 in control group (p = 0.05, R² = 0.141, β = 0.376).Conclusion. Propofol and dexmedetomidine impair the ability to retain information in short-term and, consequently, long-term memory, and propofol has a more pronounced amnesic effect, which depends on the cognitive functions of patients. The sensitivity to the amnesic effect of the drugs depends on the individual characteristics of the patients.
Levosimendan in pediatric and neonatal practice – Pro and Contra
Authors: Golomidov A. V. , Zadvornov A. A. , Ivanova A. V. , Kryuchkova O. G. , Grigoriev E. V. , Moses V. G. , Moses K. B. 
Published: June 2023

The problem of intensive shock therapy of various etiologies in neonatology remains relevant. Anatomical and physiological features of the cardiovascular system and changes that occur during the first weeks of life in children affect the choice and dose of drugs to resolve a critical condition. The shortcomings of medications available in neonatology for the correction of arterial hypotension and shock led to the search for new drugs for the treatment of such patients.Levosimendan is a cardiotonic agent that increases the sensitivity of the heart to calcium, has a positive inotropic and vasodilatory effect, reducing preload and postload of the heart. Levosimendan has been used in neonatal practice for more than 15 years, but the lack of major studies to date evaluating its effectiveness and safety in newborns significantly limits its use. Several studies have demonstrated a positive effect of the drug on cerebral, systemic perfusion and oxygenation in newborns with low cardiac output syndrome, safety, low frequency of side effects and reduced time spent in the intensive care unit for newborns after correction of heart defects and in newborns who have suffered asphyxia. However, most of the published results of the clinical use of levosimendan in neonatology are limited to a few observations or poor quality of the study design.The available literature data indicate a good potential of the drug as a means of inotropic support, however, there is no convincing data on the effect of levosimendan on the survival of newborns in critical condition.
Sistem Pemilihan Laptop Berdasarkan Kriteria Kebutuhan Dengan Metode Simple Multi Attribute Rating Technique (Smart) (Studi Kasus: Toko Laptop Guard Yogyakarta)
Authors: Setiawan Herli , Arita Witanti  
Published: June 2023

Dalam proses perdagangan yang terjadi pada Toko Laptop Guard khususnya penjualan laptop, terdapat satu masalah dalam proses pemilihan laptop dimana customer masih bingung menentukan spesifikasi laptop sesuai kebutuhan terkadang hal itu memakan waktu yang cukup lama. Salah satu sistem yang dapat membantu adalah sistem pendukung keputusan dengan metode simple multi attribute rating technique dimulai dari penentuan kriteria, memberikan bobot kriteria, melakukan normalisasi bobot kriteria, penentuan sub kriteria, memberikan bobot sub kriteria, penentuan nilai utility, menghitung nilai total dan penarikan kesimpulan berupa perangkingan atau rekomendasi akhir. adapun kriteria nya adalah jurusan kuliah, merk, aplikasi, processor dan harga. Hasil dari penelitian ini akan memberikan saran laptop yang sesuai dengan kebutuhan dengan tingkat akurasi perhitungan kebutuhan. Hasil uji coba akurasi sistem yang telah dibuat dengan perhitungan yang saat ini dilakukan oleh perusahaan dengan menggunakan sampel data sebanyak 50 data menghasilkan output 100% sesuai dan 0% tidak sesuai. Dalam Penelitian ini laptop Asus memiliki persentase pemilihan terbanyak 60%, Acer 34% dan Lenovo 6%.

Kata kunci: Laptop, Sistem Pendukung Keputusan, SMART.
Sistem Pakar Diganosa Jenis Kecanduan Narkoba Menggunakan Teorema Bayes
Authors: Setiadhi Iqbal Adji 
Published: June 2023

Pada penelitian mengenai rancangan sistem pakar untuk mendiagnosa tingkat kecanduan narkoba pada manusia dengan mengimplementasikan metode teorema bayes sebagai alat ukurnya. Teorema Bayes adalah teorema yang digunakan dalam statistika untuk menghitung peluang suatu hipotesis. Basis pengetahuan sistem pakar diperoleh dari akuisisi pengetahuan pakar yaitu pakar psikologi BNN.
Penelitian ini menggunakan 32 data yang didapat melalui rekam medis, lalu rekam medis yang ada diimplementasikan kedalam sistem. Hasil pada sistem dicocokan dengan pakar hingga mendapatkan angka kecocokan maksimal dan hasil identifikasi yang mendekati.
Berdasarkan dari 32 data yang telah diujikan terhadap pakar dan sistem, sistem dapat mendeteksi 4 jenis kecanduan narkoba yaitu Kanabis, Kokain, Opioida, dan Halusinogen . Untuk pasien yang mengalami jenis kecanduan narkoba dan sesuai dengan validasi pakar adalah 27 pasien dan yang tidak sesuai adalah 5 pasien. Sehingga untuk tingkat akurasi sistem berdasarkan hasil validasi pakar dan sistem adalah 84.38%. Sesuai.
Deteksi Tingkat Kematangan Fermentasi Singkong (Tape Singkong) Menggunakan Convolutional Neural Network (CNN)
Authors: Subayu Abdi , Supatman  
Published: June 2023

Tape merupakan makanan yang proses pembuatannya melibatkan ragi. Tidak seperti makanan-makanan lain, tape memerlukan proses fermentasi menggunakan ragi yang mengandung Kapang Amylomyces Rousi, Mucor sp, Rhizopus sp, Khamir Saccharomycopsis fibuligera, Candida Utilis, Pichia burtonii, Saccharomyces Cerevisiae, Saccharomycopsis Malanga, serta bakteri Pediococcus sp dan Bacillus sp. Tape yang mengandung unsur tersebut salah satunya adalah tape singkong (Manihot Utilissima). Permasalahan muncul ketika masyarakat awam tidak mengetahui kematangan pada fermentasi singkong. Maka dari itu, dikembangkan sebuah sistem syaraf tiruan untuk mendeteksi kematangan fermentasi singkong dengan menggunakan Metode Convolutional Neural Network (CNN). Metode CNN merupakan salah satu metode Deep Learning yang mampu melakukan proses pembelajaran mandiri untuk pengenalan objek yang diekstraksi dan diklasifikasi kemudian dapat diterapkan pada citra yang beresolusi tinggi yang memiliki model distribusi nonparametrik. Hasil dari penelitian dengan membuat 45 data latih mencapai 96.88% dan menggunakan 30 data uji tape singkong memiliki hasil mencapai 90%. Hasil ini memiliki tujuan dapat mengurangi tingkat kekeliruan masyarakat khususnya konsumen dalam menentukan kematangan pada tape singkong.
Pengembangan Geopark Nasional Indonesia menuju UNESCO Global Geopark sebagai Diplomasi Geotourism Indonesia
Authors: Hutabarat Leonard Felix 
Published: June 2023

Geopark telah dikembangkan saat ini untuk dua dekade terakhir, dan sejumlah tahapan dapat dikenal dalam perkembangannya. Bagaimana masa depan geopark global ? Sejak ditetapkan oleh UNESCO, berbagai geopark global meningkat setiap tahun. Pada tingkat negara, Indonesia hanya memiliki kurang dari 6 (enam) UNESCO Global Geoparks dibandingkan dengan kekayaan yang dimiliki dan keanekaragaman geologi yang ada di Indonesia, yang menunjukkan lokasi-lokasi warisan geologi. Pengembangan geopark nasional menuju UNESCO Global Geoparks menunjukkan menjadi salah satu instrumen yang efektif dalam pembangunan kawasan. Pembangunan UNESCO Global Geoparks tidak hanya salah satu upaya dalam mengembangkan geotourism, namun juga meningkatkan pembangunan ekonomi. Pembangunan geopark nasional Indonesia menjadi UNESCO Global Geoparks dapat menjadi salah satu upaya menghasilkan peluang kerja dan manfaat ekonomi, kesejahteraan sosial dan konservasi kawasan. Pengembangan geopark nasional Indonesia menjadi UNESCO Global Geoparks juga akan menjadi salah satu strategi dalam diplomasi geotourism Indonesia.
Kata Kunci : geopark; UNESCO Global Geopark; diplomasi; geotourism
PENERAPAN MODEL SAINTIFIK DALAM KURIKULUM 2013 UNTUK MENINGKATKAN HASIL BELAJAR SISWA
Authors: Munjana Munjana 
Published: June 2023

<p>Penelitian ini dilatar belakangi oleh hasil belajar siswa kelas V Sekolah Dasar Negeri 21 Singkawang yang rendah atau tidak mencapai kriteria ketuntasan minimal. Tujuan penelitian ini yaitu menganalisis penerapan model pembelajaran saitifik dalam kurikulum 2013 untuk meningkatkan hasil belajar siswa. Metode penelitian yang digunakan yaitu kualitatif dengan desain penelitian Tindakan kelas. Penelitian ini menggunakan dua siklus dan setiap siklusnya terdiri dari perecanaan, pelaksanaan, observasi dan refleksi. Subjek penelitian ini adalah siswa kelas V Sekolah Dasar Negeri 21 Singkawang tahun pelajaran 2020/2021 berjumlah 28 siswa. Objek penelitian adalah peningkatan hasil belajar siswa. Teknik pengumpul data yang digunakan yaitu tidak langsung. Instrumen yang digunakan adalah panduan observasi dan lembar tes formatif. Teknik analisis yang digunakan yaitu pengumpulan data, reduksi data, penyajian data dan kesimpulan. Hasil penelitian menunjukkan bahwa terdapat kenaikan rata-rata hasil belajar siswa dari siklus I ke siklus II, yaitu dari rata-rata 77 dengan kategori baik ke rata-rata 87 dengan kategori amat baik. Penelitian ini memberikan kontribusi terhadap proses pembelajaran baik dalam konteks peningkatan hasil belajar siswa maupun dalam membantu guru melaksanakan proses pembelajaran. </p>
Pengaruh Penggunaan Metode Modelling The Way Terhadap Kemampuan Pemahaman Konsep Siswa Pada Pelajaran IPS Kelas IV SDN 88 Singkawang
Authors: Putra Rizky Mandala , Setyowati Rini , Utama Erdi Guna 
Published: June 2023

<p>Penelitian ini bertujuan untuk mendapatkan Perbedaan kemampuan metode <em>Modelling The Way</em> terhadap kemampuan pemahaman konsep IPS siswa antara kelas yang diberikan metode <em>Modelling The Way </em>dengan kelas yang diberikan model pembelajaran langsung. untuk mengetahui pengaruh metode <em>Modelling The Way </em>terhadap pemahaman konsep IPS siswa. untuk mengetahui motivasi belajar siswa setelah menggunakan metode <em>Modelling The Way. </em>Jenis penelitian yang digunakan yaitu kuantitatif dengan metode penelitian eksperimen. Desain penelitian yang digunakan adalah <em>eksperimen semu</em> dengan bentuk <em>the posttest only design with nonequevalent group</em>. Populasi dalam penelitian ini adalah seluruh siswa kelas IV SDN 88 Singkawang. Sampel diambil yaitu <em>Sampling Purposive, </em>jumlah masing-masing kelompok 26 orang dikelompokkan menjadi dua kelas yaitu kelas 4A sebagai kelas eksperimen yang menggunakan metode <em>Modelling The Way</em> dan kelas 4B sebagai kelas kontrol yang menggunakan model pembelajaran langsung. Pengumpulan data menggunakan tes dan non tes. Data hasil penelitian ini dianalisis dengan uji statistic, Uji t, <em>effect size </em>dan rumus persentase. Terdapat perbedaan bahwa nilai <em>t<sub>hitung</sub></em>= 2,208 dengan nilai <em>t<sub>tabel</sub></em> = 2,004 untuk α = 5% dan dk = 50. Hasil penelitian menunjukkan bahwa : 1) untuk mengetahui perbedaan pemahaman konsep siswa antara kelas yang menggunakan metode pembelajaran <em>Modelling The Way </em>dengan kelas yang menggunakan pembelajaran langsung pada pelajaran IPS kelas IV SDN 88 singkawang. 2) pengaruh metode <em>Modelling The Way</em> terhadap kemampuan pemahaman konsep IPS sebesar 0,9 dengan kategori tinggi. 3.) Motivasi siswa berada pada ketegori tinggi dengan rata-rata sebesar 74,615. </p>
Pengaruh Pengunaan Model Pembelajaran Time Token Terhadap Hasil Belajar Siswa
Authors: Maharani Syarina , Syaflin Sylvia Lara , Hermansah Bambang 
Published: June 2023

<p><span lang="EN-US">penelitian ini bertujuan untuk melihat pengaruh pengunaan model pembelajaran <em>time token </em>terhadap hasilbelajar siswa tema 7 kelas V SDN 3 srikaton. Desain penelitian ini ialah penelitian <em>pre exsperimental </em>dengan rancangan <em>the one group pretest-posttest design.</em> Populasi penelitian ini yaitu semua siswa kelas V SDN 3 srikaton yang berjumlah 22 orang. Sampel ini ditentukan dengan menggunakan sampling jenuh. Sampel ini terdiri dari semua siswa kelas IV dengan jumlah kurang 22 siswa. Pengumpulan data dilakukan dengan menggunakan metode tes dalam bentuk tes objektif <em>essay</em>. Data yang diperoleh dianalisis menggunakan uji <em>pired sample t test. </em>Hasil analisis data diperoleh </span><span lang="EN-US"> = 0,000 lebih kecil dari </span><span lang="EN-US"> = 0,432 dengan taraf signifikansi 5%. Hasil penelitian menunjukkan terdapat pengaruh yang signifikan antara model pembelajaran <em>time token </em>terhadap hasil belajar siswa pada tema peristiwa dalam kehidupan di kelas v sdn 3 srikaton tahun pembelajaran 2021/2022.</span></p>
Сognitive Functioning in Patients with the Phenomenon of Anhedonia in the Framework of Affective Pathology and Schizophrenia Spectrum Disorders
Authors: Popov M. M. , Sorokin S. A. , Kananovich P. S. 
Published: June 2023

Background: anhedonia is a transdiagnostic psychopathological phenomenon, which is assessed as “core” for several diseases at once — ﬁrst of all schizophrenic and affective spectrum disorders. The problem of clinical features differentiation and identiﬁcation of anhedonia’s neurobiological mechanisms in the structure of the affective and schizophrenic spectrum disorders is still topical and far from being resolved.The aim of the study: to compare the relationship between the features of neurocognitive functioning and the manifestations of anhedonia among patients with disorders of the schizophrenic and affective spectra.Patients: the sample consisted of 40 patients including 17 patients with schizophrenic spectrum disorders (ICD-10 diagnosis codes F20.01, F20.02, F21.3, F21.4, F25.0, F25.1) and 23 patients with affective disorders (ICD-10 diagnosis code F33, F31).Methods: clinical, psychometric, experimental psychological and statistical.Results: patients with schizophrenia spectrum disorders show lower scores on pleasure anticipation ability and ability to experience pleasure in the social sphere. The affective spectrum group showed a correlation between anticipatory anhedonia and phonetic verbal ﬂuency (r = –0.487; p < 0.01). There was also a correlation between immediate pleasure experience and errors in the Rey ﬁgure test (r = –0.349; p < 0.05). Social anhedonia in these patients was associated with phonetic verbal ﬂuency productivity (r = –0.509; p < 0.01) and performance in visual ﬂuency productivity (r = –0.473; p < 0.01). Patients with schizophrenia spectrum disorders had a correlation between anticipatory anhedonia and the Color-Word Interference Test (r = –0.329; p < 0.05) and the Rey Complex Figure Test (r = –0.307; p < 0.05). Consummatory anhedonia was correlated with verbal ﬂuency test (r = –0.511; p < 0.01) and the Rey Complex Figure Test (r = –0.417; p < 0.01). Social anhedonia was correlated with Color-Word Interference Test (r = –0.656; p < 0.01), verbal ﬂuency (r = –0.523; p < 0.01), and story description (r = –0.421; p < 0.01).Conclusion: manifestations of different parameters of anhedonia demonstrate the differences in schizophrenia and affective spectrum disorders. Patients with schizophrenia spectrum disorders have greater difﬁculties in anticipating pleasure and experiencing pleasure in the social sphere. The ability to anticipate pleasure may be associated with executive function, while the ability to experience pleasure immediately may be associated with memory function. Social anhedonia affects a wide range of cognitive functions.
Catatonia in the Structure of Affective and Schizoaffective Disorders of the Postpartum Period
Authors: Piskarev M. V. , Lobanova V. M. , Rumyantseva E. B. 
Published: June 2023

Background: аt the present stage of psychiatry, within the framework of the dimensional paradigm, catatonia is considered as a transnosological entity that manifests within the clinical space of various affective and schizoaffective disorders. In the 21st century studies, devoted to the analysis of motor disorders that appear in the clinical space of postpartum affective and schizoaffective disorders, become increasingly relevant (J.Y. Lai, T.L. Huang, 2004; A. Nahar and et al., 2017; C. Kamau, 2017; L. Csihi and et al., 2022). However, research on this issue is very limited. The objective: the analysis of catatonic phenomenon, manifesting in the postpartum period, based on the observations of three clinical cases.Patients and methods: 3 clinical cases of patients, undergoing treatment in the clinical department of the FSBSI “Mental Health Research Centre” with established diagnoses of bipolar affective disorder (ICD-10: F31.1; 1 case) and schizoaffective disorder (ICD-10: F25.2; 2 cases) with a predominance of motor disorders in the clinical picture of the disease. The main method was clinical with the use of psychological examination and data from instrumental (EEG) diagnostics.Results: movement disorders registered in the structure of apathoanesthetic depressions within the exacerbation of bipolar affective disorder are represented by the phenomena of hypokinetic catatonia and act as an ampliﬁer of affective disorders. Catatonic symptoms within the clinical space of schizoaffective disorders, are limited by manifestations of parakinetic catatonia, do not have a direct correlation with the structure and severity of affective disorders, and indicate an increase in the progredient endogenous process.Conclusion: the analysis of clinical observations testiﬁes in favor of the heterogeneity of affective-catatonic states not only in terms of the structure of motor phenomena, but also in terms of the psychopathological proﬁle of affective disorders.