bluuebunny/crossref_metadata_2025_split huggingface dataset:
PREPARATION AND CHARACTERIZATION OF HYDROXYAPATITE BY CHEMICAL TREATMENT
Authors: Oyewumi-Musa Rukayat Titilayo , Bello M. O. , Abdus-Salam Nasiru , Olabode Sururat Olaitan 
Published: August 2023

Hydroxyapatite powder (HA) was prepared using the chemical precipitation method using diammonium hydrogen phosphate and calcium nitrate tetrahydrate as the starting materials. The solution was kept stirring for 24hrs at room temperature, white precipitates were dried and calcined at 1000ºC and 1200ºC for 4hrs. The powder sample was characterized by scanning electron microscopy (SEM), Fourier infrared spectroscopy (FTIR), X-ray diffraction (XRD), Elemental dispersive X-ray (EDX). The results showed that obtained HA powders were greatly influenced by synthetic conditions. SEM shows the morphology of crystals structure, large pores sizes were observed at 50µm and 100µm. The FTIR shows the presence of CO32- at 1390 cm-1 and 1384 cm-1 which may be due to the adsorption of atmospheric CO2 on the surface of HA. PO42- was observed at 1046 cm-1 and 1092 cm-1. The EDX shows the presence of C, O, Na, Mg, Al, P, Ca. The histogram of EDX revealed oxygen carbon, phosphorus, and calcium as the major elements, sodium, magnesium, and aluminum were also present.
Efektifitas Video Pembelajaran Bantuan Hidup Dasar pada Henti Jantung dengan Model Selamat terhadap Pengetahuan Masyarakat Kota Pontianak
Authors: Hidayat Uti Rusdian , Hatmalyakin Debby , Alfikrie Fauzan 
Published: August 2023

ABSTRACT The high incidence of Out of Hospital Cardiac Arrest (OHCA) requires not only many prevention programs but also fast and appropriate initial treatment to make victims survive. In fact, the phenomenon of OHCA strongly involves the role of lay people (not medical personnel) who are around the victim's location. This study aims to determine the effectiveness of basic life support learning videos in cardiac arrest with the SELAMAT model on the knowledge of the Pontianak City Community. The research method used quasy experimental with a sample size of 70 respondents. The research data was collected using an online questionnaire with google form Statistical analysis uses the wilcoxon test. The results showed that video media can increase public knowledge in performing basic life support (p=0.000). It is expected that the government or related agencies can work together in socializing the SELAMAT Model learning video to increase public knowledge about basic life support in cardiac arrest victims. Keywords: Video, Cardiac Arrest, Basic Life Support, SELAMAT Model ABSTRAK Tingginya angka kejadian Out of Hospital Cardiac Arrest (OHCA) membutuhkan tidak hanya banyak program pencegahan namun juga penanganan awal yang cepat dan tepat untuk membuat korban tetap dapat bertahan hidup. Faktanya, fenomena OHCA sangat melibatkan peran orang awam (bukan tenaga medis) yang berada di sekitar lokasi korban. Penelitian ini bertujuan untuk mengetahui efektifitas video pembelajaran bantuan hidup dasar pada henti jantung dengan model SELAMAT terhadap pengetahuan Masyarakat Kota Pontianak. Metode penelitian meggunakan quasy experimental dengan jumlah sampel sebanyak 70 responden. Data penelitian dikumpulkan menggunakan kuesioner online dengan google form. Analisis statistik menggunakan uji wilcoxon. Hasil penelitian menunjukkan bahwa media video dapat meningkatkan pengetahuan masyarakat dalam melakukan bantuan hidup dasar (p=0,000). Diharapkan pemerintah atau instansi terkait dapat bekerjasama dalam mensosialisasikan video pembelajaran Model SELAMAT untuk meningkatkan pengetahuan masyarakat tentang bantuan hidup dasar pada korban henti jantung. Kata Kunci: Video, Henti Jantung, Bantuan Hidup Dasar, Model SELAMAT
Abses Epidural sebagai Komplikasi Sinusitis Pada Anak: Laporan Kasus
Authors: Satyanegara William Gilbert , Sampurno Dana Profit , Jatinugroho Yusuf Damar , Surya Guntur , Singh Arwinder , Halim Hendy 
Published: August 2023

ABSTRACT Intracranial complications from sinusitis are rare and can be life-threatening. Children have a higher risk of developing complications and difficult to recognize their signs and symptoms. A 14-year-old child presented with complaints of severe pain in the right ear and fever. The patient had a history of trauma to the right nose 2 years ago, controlled asthma, and an allergy to humid air. Painkillers were given which did not improve, followed by advanced radiology. The results showed an epidural abscess accompanied by sinusitis on the right frontal. Craniotomy followed by antibiotic therapy was performed as well as an evaluation of the patient's symptoms. Epidural abscess is a rare intracranial complication, and its recognition is quite tricky, requiring supporting examination and good teamwork. Early recognition and adequate therapy can prevent morbidity and mortality. Keywords: Epidrual Abscess, Intracranial, Rhinosinusitis ABSTRAK Komplikasi intrakranial dari sinusitis merupakan kejadian yang jarang dan dapat mengancam nyawa. Anak-anak memiliki risiko yang lebih tinggi mengalami komplikasi serta sulit dikenali tanda dan gejalanya. Seorang anak 14 tahun datang dengan keluhan nyeri hebat pada telinga kanan sejak dan demam. Pasien memiliki riwayat trauma pada hidung kanan 2 tahun lalu, asma terkontrol, dan alergi terhadap udara lembab. Pemberian anti-nyeri yang tidak membaik, diikuti dengan radiologi lanjut. Hasilnya menunjukan terdapat abses epidural diserai dengan sinusitis pada frontal kanan. Pembedahan, diikuti dengan terapi antibiotik dilakukan serta evaluasi gejala pasien. Abses epidural merupakan komplikasi intrakranial yang jarang terjadi, dan pengenalannya cukup sulit sehingga membutuhkan pemeriksaan penunjang dan kerjasama tim yang baik. Pemberian terapi yang tepat dan adekuat dapat mencegah kesakitan dan kematian. Kata Kunci: Abses Epidural, Intrakranial, Rinosinusitis
Hubungan Discharge Planning dengan Pengetahuan terhadap Ibu tentang Perawatan Kejang Demam
Authors: Gea Happy Kristiani , Putri Lidia Ayu , Situmorang Juliana Prome , Manik Suriati , Sembiring Roslinda 
Published: August 2023

ABSTRACT Febrile seizures are seizures that occur due to an increase in body temperature (rectal temperature is above 38 ° C) due to an extracranial process in the absence of intracranial infection or other causes. Febrile seizures often occur in children aged 6 months to 5 years because in toddlers the immune system is still low (Wilson, 2016). To find out the Relationship between Dischrage Planning and Knowledge of Mothers About Treatment of Fever Seizures. This type of quantitative research is a quasi-experimental method. Quasi experiment (quasi experiment). The One-Group Pretest-Posttest Design research method was carried out on one group without a control group. The total sample of respondents is 30 people. The research location is at the Dandy Pratama Clinic, Mabar, Medan Deli, North Sumatra. From the results of the chi square test, the asymp.sig value, the p value of 0,000<0.05 means that ho is rejected and ha is accepted because there is a relationship bwtween discharge planning and knowladge of mothers about the treatment of febrile seizures. Keywords: Febrile seizure, Knowledge, Mother ABSTRAK Kejang demam adalah bangkitan kejang yang terjadi karena adanya kenaikan suhu tubuh (suhu rektal berada diatas 38˚ C) akibat suatu proses ekstrakranium tanpa adanya infeksi intrakranial atau penyebab lain. Kejang demam sering terjadi pada anak usia 6 bulan sampai 5 tahun karena pada balita kekebalan tubuh masih rendah (wilson, 2016). Untuk mengetahui Hubungan Dischrage Planning Dengan Pengetahun Terhadap Ibu Tentang Perawatan Kejang Demam. Jenis penelitian kuantitatif dengan metode eksperimen semu (quasi experiment). Eksperimen semu (quasi experiment). Metode penelitian One-Group Pretest-Posttest Design ini dilakukan terhadap satu kelompok tanpa adanya kelompok kontrol. Jumlah sampel responden sebanyak 30 orang. Lokasi penelitian di klinik pratama dandy, mabar, medan deli, sumatera utara. Pengumpulan data dengan memberikan kuesioner dan penyuluhan Dari hasil uji chi square nilai asymp.sig p value 0,000 < 0,05 berarti Ho ditolak dan Ha diterima karena adanya hubungan discharge planning dengan pengetahuan terhadap ibu tentang perawatan kejang demam.Kata Kunci: Kejang Demam, Pengetahuan, Ibu
Perubahan Perilaku Ibu Hamil terhadap Upaya Pencegahan Stunting melalui Edukasi dengan Pendekatan Hipnoterapi
Authors: Rahim Rachmawati , Muslimin Irma 
Published: August 2023

ABSTRACT The prevalence of stunting in Indonesia is still fifth after India, which is 27.7% which means it is still far above the WHO standard, which is below 20%. West Sulawesi still ranks second in the highest stunting rate in Indonesia, therefore various efforts have been made to reduce the incidence of stunting in West Sulawesi. The purpose of this study was to analyze the effect of providing education with a family approach and hypnotherapy on behavioral changes in pregnant women in preventing stunting. The method of research is quasi-experimental using a non-randomized pre-test and post-test with a controlled group design. Sampling using a purposive sampling technique. Data were analyzed using the paired t-test with a significance level of p<0.05. The results of this study indicate that there is a change in behavior in mothers with the hypnotherapy approach when compared to behavior in pregnant women in control cases. There is a change in behavior in mothers with the hypnotherapy approach when compared to behavior in pregnant women in control cases Keywords : Hypnotherapy, Pregnant Mother, Knowledge, Behavior ABSTRAK Prevalensi stunting di Indonesia masih berada apa urutan kelima setelah India yaitu sebanyak 27,7 % dan berarti masih jauh di atas standar WHO yaitu dibawah 20%. Sulawesi Barat masih menduduki urutan kedua dengan prevalensi stunting tertinggi di Indonesia setelah Nusa Tenggara Timur, oleh karena itu pemerintah telah melakukan upaya telah dilakukan untuk menurunkan angka kejadian stunting di Sulawesi Barat. Tujuan penelitian ini adalah adalah menganalisis pengaruh pemberian edukasi dengan pendekatan keluarga dan hipnoterapi terhadap perubahan perilaku ibu hamil dalam pencegahan stunting.Metode Penelitian adalah Quasi eksperimen dengan menggunakan NonRandomized Pre-test Post Test with controlled Group Design. Pengambilan sampel dengan menggunakan teknik purposive sampling. Data dianalisis menggunakan uji paired t test dengan tingkat kemaknaan p<0,05. Hasil penelitian ini membuktikan bahwa terjadi perubahan perilaku pada ibu dengan pendekatan hipnoterapi jika dibandingkan dengan perilaku pada ibu hamil pada kasus kontrol. Bahwa terjadi perubahan perilaku pada ibu dengan pendekatan hipnoterapi jika dibandingkan dengan perilaku pada ibu hamil pada kasus kontrol Kata kunci: Hipnoterapi, Ibu Hamil, Pengetahuan, Perilaku
PROSPEK PENGEMBANGAN USAHATANI LADA (Piper Nigrum L) (Studi Kasus di Desa Pebaloran, Kecamatan Curio, Kabupaten Enrekang)
Authors: Rosida Rosida , Busaeri Sitti Rahbiah , Ilsan Mais 
Published: August 2023

Tujuan penelitian ini adalah: (1) menganalisis tingkat produksi dan pendapatan usahatani lada di Desa Pebaloran, Kecamatan Curio, Kabupaten Enrekang. (2) Menganalisis prospek perkembangan produksi dan luas lahan usahatani lada di Desa Pebaloran, Kecamatan Curio, Kabupaten Enrekang. Penelitian ini dilaksanakan di Desa Pebaloran, Kecamatan Curio, Kabupaten Enrekang, Provinsi Sulawesi Selatan. Pemilihan lokasi penelitian karena merupakan salah satu desa dengan luas areal perkebunan lada yang cukup besar dan merupakan pengembangan wilayah komoditi lada. Waktu penelitian ini dilakukan selama 3 bulan mulai dari Januari sampai dengan Maret 2018. Penentuan sampel penelitian menggunakan metode acak sederhana (Simple Random Sampling). jumlah sampel petani yang dipilih sebanyak 10% dari jumlah populasi. Populasi penelitian adalah petani lada yang aktif dalam kelompok tani berjumlah 296 orang dan jumlah sampel yang digunakan dalam penelitian ini yaitu sebanyak 30 orang. Metode analisis yang digunakan yaitu analisis pendapatan, analisis Trend. Hasil penelitian menunjukkan bahwa: (1) jumlah produksi lada yang didapatkan oleh petani lada yaitu 407 kg/ha, sedangkan besarnya pendapatan yang didapatkan oleh petani adalah Rp 18.413.229/petani. (2) tanaman lada di Desa Pebaloran, Kecamatan Curio, Kabupaten Enrekang mempunyai prospek yang baik untuk pengembangan lada di masa yang akan datang.
Prevalencia de la hemofilia a en la provincia Bolívar
Authors: Castro Naranjo Genesis Alejandra , Naranjo Chávez Gladys Magdalena 
Published: August 2023

Introducción: la hemofilia es un trastorno hereditario que se caracteriza por la deficiencia de los factores de coagulación, las deficiencias del factor VIII (Hemofilia A) y del factor IX (Hemofilia B) son una de las patologías más frecuentes y conocidas en el área de coagulación. Objetivo: el objetivo de investigación Determinar la prevalencia de la Hemofilia A, en el Hospital Alfredo Noboa Montenegro. Métodos: La unidad de análisis: Historia clínica del paciente con hemofilia y atendido en el hospital Alfredo Noboa Montenegro. Metodología: se incluye a los 20 registrados al ser un número óptimo para el estudio. Resultados: los pacientes con Hemofilia A fueron se tiene que el 85% que representan 17 pacientes tienen como antecedente familiar Hemofilia A; 2 (10%) de ellos tienen antecedentes familiares de ECV y solo 1 (5%) de ellos tiene HTA. el 95% que tienen Hemofilia A son hombres, mientras que el 5% que representa a un paciente es mujer. El 70% presentaron riesgo de sangrado leve, un (25%) riesgo moderado y un (5) % con riesgo severo. Conclusiones: la prevalencia de la hemofilia a en el hospital Alfredo Noboa Montenegro es baja, ya que en este estudio se cuenta con solo 20 pacientes. la prevalencia de la hepatitis a fue de 95 % mayoritariamente en varones, y la mayor prevalencia de pacientes se encontró en las edades de 15_24 anos.
S1
Authors: MUQODDAM MUQODDAM MUQODDAM 
Published: August 2023

Pemilihan media pembelajaran dan media berupa buku pelajaran teks biografi yang tepat akan berpengaruh positif terhadap hasil pembelajaran peserta didik. Terlebih dalam pembelajaran bahasa dan sastra Indonesia, masih banyak di jumpai peserta didik yang nilainya rendah. Hal tersebut berkaitan dengan kesalahan dalam memilih media pembelajaran. Terkait dengan permasalahan tersebut maka peneliti berupaya akan mengembangkan suatu media buku pelajaran. Metode pengembangan yang digunakan terdiri dari lima langkah pengembangan yaitu: 1) Analysis, 2) Desaign, 3) Development, 4) Implementation, 5) Evaluation. Produk hasil perkembangan divalidasikan kepada ahli bahasa, ahli materi dan ahli desain untuk mengetahui tingkat kelayakan produk media pada materi teks biografi. Hasil penelitian Pengembangan media pembelajaran teks biografi dengan menggunakan media pembelajran projek based learning yang berbentuk buku pelajaran untuk siswa kelas X MA NU Pakis Malang mendapatkan nilai untuk hasil uji ahli bahasa 3,33, hasil uji ahli materi mencapai 3,45 dan hasil uji ahli desain 3,81. Dari hal tersebut terbukti bahwa bahan ajar teks biografi dengan menggunakan media pembelajaran berbasis project learning sangat efektif di implementasikan untuk kelas X MA NU.
Functional characterization of VirB/VirD4 and Icm/Dot type IV secretion systems from the plant-pathogenic bacterium Xanthomonas euvesicatoria
Authors: Drehkopf Sabine , Scheibner Felix , Büttner Daniela 
Published: August 2023

IntroductionMany Gram-negative plant- and animal-pathogenic bacteria employ type IV secretion (T4S) systems to transport proteins or DNA/protein complexes into eukaryotic or bacterial target cells. T4S systems have been divided into minimized and expanded T4S systems and resemble the VirB/VirD4 T4S system from the plant pathogen Agrobacterium tumefaciens and the Icm/Dot T4S system from the human pathogen Legionella pneumophila, respectively. The only known plant pathogen with both types of T4S systems is Xanthomonas euvesicatoria which is the causal agent of bacterial spot disease on pepper and tomato plants.Results and discussionIn the present study, we show that virB/virD4 and icm/dot T4S genes are expressed and encode components of oligomeric complexes corresponding to known assemblies of VirB/VirD4 and Icm/Dot proteins. Both T4S systems are dispensable for the interaction of X. euvesicatoria with its host plants and do not seem to confer contact-dependent lysis of other bacteria, which was previously shown for the chromosomally encoded VirB/VirD4 T4S system from Xanthomonas axonopodis pv. citri. The corresponding chromosomal T4S gene cluster from X. euvesicatoria is incomplete, however, the second plasmid-localized vir gene cluster encodes a functional VirB/VirD4 T4S system which contributes to plasmid transfer. In agreement with this finding, we identified the predicted relaxase TraI as substrate of the T4S systems from X. euvesicatoria. TraI and additional candidate T4S substrates with homology to T4S effectors from X. axonopodis pv. citri interact with the T4S coupling protein VirD4. Interestingly, however, the predicted C-terminal VirD4-binding sites are not sufficient for T4S, suggesting the contribution of additional yet unknown mechanisms to the targeting of T4S substrates from X. euvesicatoria to both VirB/VirD4 and Icm/Dot T4S systems.
Immune modulation of Th1/Th2/Treg/Th17/Th9/Th21 cells in rabbits infected with Eimeria stiedai
Authors: Chen Xiao-Di , Xie Jing , Wei Yong , Yu Ji-Feng , Cao Ye , Xiao Lu , Wu Xue-Jing , Mao Cong-Jian , Kang Run-Min , Ye Yong-Gang 
Published: August 2023

IntroductionDespite long-term integrated control programs for Eimeria stiedai infection in China, hepatic coccidiosis in rabbits persists. Th1, Th2, Th17, Treg, Th9, and Th21 cells are involved in immune responses during pathogen infection. It is unclear whether Th cell subsets are also involved in E. stiedai infection. Their roles in the immunopathology of this infection remain unknown. Therefore, monitoring these T-cell subsets’ immune responses during primary infection of E. stiedai at both transcriptional (mRNA) and protein (cytokines) levels is essential.MethodsIn experimentally infected New Zealand white rabbits, mRNA expression levels of their transcript—TBX2 (Th1), GATA3 (Th2), RORC (Th17), Foxp3 (Treg), SPI1 (Th9), and BCL6 (Th21)—were evaluated using quantitative real-time polymerase chain reaction (qRT-PCR), whereas Th1 (IFN-g and TNF-a), Th2 (IL4), Th17 (IL17A and IL6), Treg (IL10 and TGF-b1), Th9 (IL9), and Th21 (IL21) cytokines were measured using enzyme-linked immunosorbent assays (ELISAs).ResultsWe found that levels of TBX2, GATA3, RORC, SPI1, and BCL6 in the livers of infected rabbits were elevated on days 5 and 15 post-infection (PI). The concentrations of their distinctive cytokines IFN-g and TNF-a for Th1, IL4 for Th2, IL17A for Th17, IL9 for Th9, IL21 for Th21, and IL10 for Treg IL10 were also significantly increased on days 5 and 15 PI, respectively (p &lt; 0.05). On day 23 PI, GATA3 with its cytokine IL4, RORC with IL17A, Foxp3 with IL10 and TGF-b1, and SPI1 with IL9 were significantly decreased, but TBX2 with IFN-g and IL6 remained elevated.DiscussionOur findings are the first evidence of Th1/Th2/Treg/Th17/Th9/Th21 changes in E. stiedai-infected rabbits and provide insights into immune regulation mechanisms and possible vaccine development.
Prevalence and impact of myocardial injury among patients hospitalized with COVID-19
Authors: Vu Vu Hoang , Nguyen Thanh Cong , Pham Quang Dang Duy , Pham Dan Ngoc , Le Le Bao , Le Khoi Minh 
Published: August 2023

BackgroundMyocardial injury is a prevalent complication observed in patients hospitalized with COVID-19 and is strongly associated with severe illness and in-hospital mortality. However, the long-term consequences of myocardial injury on clinical outcomes remain poorly understood. This study aimed to assess the impact of myocardial injury on both acute-phase and long-term prognosis in COVID-19 patients.MethodsA retrospective, observational study was conducted on all patients who received treatment at the Intensive Care Center for COVID-19 patient, University Medical Center Ho Chi Minh City (UCICC), from August 3rd, 2021, to October 28th, 2021.ResultsA total of 582 patients were enrolled in the study, of which 55.3% were female. The mean age of participants was 63.3 ± 16.2. Out of these patients, 330 cases (56.8%) showed myocardial injury. Compared to patients without myocardial injury, those with myocardial injury were older and had a higher incidence of chronic diseases including hypertension, ischemic heart disease, atrial fibrillation, heart failure, diabetes mellitus, chronic kidney disease. They also presented with more severe respiratory failure upon admission and showed a more pronounced abnormality in inflammation and kidney function tests. Furthermore, the in-hospital mortality rate was significantly higher in the group with myocardial injury (49.7% vs 14.3%, p &lt; 0.001). After adjusting for age, gender, comorbidities, renal function, and disease severity at admission, myocardial injury emerged as an independent risk factor for in-hospital mortality (OR = 3.758, 95% CI 1.854–7.678, p &lt; 0.001). Among successfully discharged COVID-19 patients, the all-cause mortality rate after a median follow-up of 18.4 months was 7.9%. Patients with myocardial injury had a significantly higher long-term mortality rate compared to those without myocardial injury (14.0% vs. 3.2%, p &lt; 0.001). However, multivariable Cox regression analysis did not find myocardial injury to be a significant predictor of long-term mortality (HR = 2.128, 95% CI 0.792–5.712, p = 0.134).ConclusionsMyocardial injury is a common and serious complication in hospitalized COVID-19 patients, associated with increased in-hospital mortality. However, it does not significantly impact long-term mortality in successfully discharged COVID-19 patients.
Incidence of atrioventricular block after isolated coronary artery bypass grafting: a systematic review and pooled-analysis
Authors: Yaghoobian Ramin , Hosseini Dolama Reza , Soleimani Hamidreza , Saeidi Sahar , Mashayekhi Mahtab , Mirzayi Parsa , Alavi Tabatabaei Ghazaal , Hosseini Kaveh 
Published: August 2023

Background and objectivesAtrioventricular block (AVB) is a serious complication following coronary artery bypass grafting (CABG) surgery, and its high-grade form may necessitate the implantation of a permanent pacemaker (PPM). AVB is associated with increased morbidity and mortality rates. This study aims to estimate the incidence of AVB and subsequent PPM implantation after isolated CABG surgery.Material and methodsWe searched electronic databases of PubMed, Embase, and Scopus from inception to 18 November 2022. Clinical trials and observational studies reporting the incidence of post-CABG AVB or subsequent PPM implantation in adult patients were included. The total incidence for all included outcomes was calculated using the inverse variance method, and the I2 statistic was reported to evaluate the heterogeneity of studies.ResultsA total of 28 studies met the inclusion criteria. Four studies [3 cohorts, 1 randomized controlled trial (RCT)] reported AVB without specifying its type; one (cohort) reported different degrees of AVB, 20 (12 cohorts, 8 RCTs) reported complete heart block (CHB) (or AVB requiring temporary pacing), and nine (8 cohorts, 1 RCT) reported the number of PPM inserted due to AVB. The pooled incidence of AVB, CHB (or AVB requiring temporary pacing), and PPM due to AVB was 1.16%, 1.73%, and 0.58%, respectively. Meta-regression analysis revealed that age, gender, diabetes, hypertension, hyperlipidemia, or smoking were not significantly associated with AVB, CHB, or PPM implantation.ConclusionThis study highlights the incidence of AVB and the need for PPM implantation following CABG surgery. The findings emphasize the importance of postoperative monitoring and surveillance to improve patient outcomes.
Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022377181, identifier PROSPERO CRD42022377181.