bluuebunny/crossref_metadata_2025_split huggingface dataset:
Examining energy and nutrient production across the different agroecological zones in rural Ethiopia using statistical methods
Authors: Guja Habtamu , Belgiu Mariana , Embibel Lidya , Baye Kaleab , Stein Alfred 
Published: September 2023

AbstractPoor‐quality diets are of huge concern in areas where consumption is dominated by locally sourced foods that provide inadequate nutrients. In agroecologically diverse countries like Ethiopia, food production is also likely to vary spatially. Yet, little is known about how nutrient production varies by agroecology. Our study looked at the adequacy of essential nutrients from local production in the midland, highland, and upper highland agroecological zones (AEZs). Data were collected at the village level from the kebele agriculture office and at the farm and household levels through surveys in rural districts of the South Wollo zone, Ethiopia. Household data were acquired from 478 households, and crop samples were collected from 120 plots during the 2020 production year. Annual crop and livestock production across the three AEZs was converted into energy and nutrient supply using locally developed crops' energy and nutrient composition data. The total produced energy (kcal) met significant proportions of per capita energy demand in the highland and upper highland, while the supply had a 50% energy deficit in the midland. Shortfalls in per capita vitamin A supply decreased across the agroecological gradient from midland (46%) to upper highland (31%). The estimated shortfall in folate supply was significantly higher in the upper highlands (63%) and negligible in the highlands (2%). The risk of deficient iron and zinc supply was relatively low across all AEZs (<10%), but the deficiency risk of calcium was unacceptably high. Agroecology determines the choice of crop produced and, in this way, affects the available supply of energy and nutrients. Therefore, agroecological variations should be a key consideration when designing food system interventions dedicated to improving diets.
Performances, carcass characteristics, and economic benefit of yearling Hararghe highland rams fed diet containing concentrate mixtures and sugarcane bagasse or rice husk treated with Trichoderma viride and effective microorganisms
Authors: Begna Regasa , Urge Mengistu , Negesse Tegene , Animut Getachew 
Published: September 2023

AbstractThe productivity of small ruminants in Ethiopia is low due to a shortage of feed supply throughout the year, both in terms of quality and quantity. This problem leads to the utilization of locally available lignocellulose by‐products, which encompass high cellulose, hemicellulose, and lignin. It is known that the nutritive value of these lignocellulose by‐products can be improved through biological, chemical, or a combination of both treatments This study was aimed at evaluating body weight change, carcass characteristics, and economic efficiency of rams fed a total mixed diet containing biologically treated rice husk (RH) or sugarcane bagasse (SCB). Thirty‐six sheep, weighing an average initial body weight of 18 ± 1.8 kg were used. Two feeds (SCB and RH) and three biological treatments (Control, Trichoderma viride [Tv], and effective microbes [EM]) were used with a randomized complete block design (RCBD) in 2 × 3 factorial arrangements. Ram fed on RH containing diets had higher dry matter intake (DMI) (g/h/day), DMI (% of BW), DMI (g/kg BW0.75), average daily gain (ADG) (106 vs. 53 g/day), and feed conversion efficiency (FCE) (0.107 vs. 0.076) than SCB containing diets. Ram fed diets containing biologically treated roughages had significantly higher (p < .05) DMI (g/h/day), DMI (% of BW), DMI (g/kg BW0.75), ADG, and FCE. However, no significant differences were observed between sheep fed diets containing EM and Tv in DMI (g/h/day), DMI (% of BW), DMI (g/kg BW0.75), ADG, and FCE. This study also revealed that significantly (p < .05) higher carcass weight, dressing percentage (DP), rib eye muscle area, total non‐carcass fat, and total edible offal components had been recorded for rams fed diets containing RH as roughage source related to rams fed diets containing SCB. While other parameters were unaffected by treatments, sheep fed diets containing biologically treated feed had a higher hot carcass weight plus DP. However, no significant (p > .05) difference was found between diets based on biologically treated roughage. Profitability analysis indicated that sheep fattening on a diet containing RH and by‐products treated with Tv and EM showed greater profitability than untreated SCB. The authors had concluded that fattening sheep on diets containing RH results in higher feed intake, better body weight gain, more carcasses and higher profits, but optimum inclusion levels need further research, for either treated or untreated SCB.
Quality preservation and decay reduction of minimally processed seedless barberry fruit via postharvest ultrasonic treatment
Authors: Saebi Mohammad Reza , Moradinezhad Farid , Ansarifar Elham 
Published: September 2023

AbstractSeedless barberry fruit is one of the important horticultural products of Iran, which has health benefits due to great amounts of phenolic compounds, flavonoids, and antioxidant activity. However, fresh barberry fruit has a short shelf life even at cold storage, mainly due to high water content and thin skin that leads to fungal decay and high postharvest loss. We examined the effectiveness of the postharvest ultrasonic technology on the quality preservation and nutritional value of fresh seedless barberry fruit and their decay reduction during cold storage. Experimental treatments were the time and temperature of ultrasound (US) and included: (1) control, fruit without US, (2) 5 min US at 20°C, (3) 5 min US at 30°C, (4) 5 min US at 40°C, (5) 10 min US at 20°C, (6) 10 min US at 30°C, (7) 10 min US at 40°C, (8) 15 min US at 20°C, (9) 15 min US at 30°C, and (10) 15 min US at 40°C. After applying the treatments, the fruits were sealed in polyethylene bags and stored at 4 ± 1°C for 20 days. The results showed that all US treatments had higher titratable acidity, antioxidant activity, phenol content, and vitamin C content than the control. However, the highest titratable acidity and antioxidant activity values were obtained in US treatments at 40°C and 30°C for 15 min. Also, US treatment significantly reduced the total soluble solids, decay percentage, and microbial load of fresh barberry fruit. As the US treatment temperature increased from 20°C to 40°C, the decay and microbial load of fruit significantly decreased. In conclusion, this study proved the potential application of the US for preserving the quality of fresh seedless barberry fruit, and the most optimal US temperature and its application time was 40°C for 15 min.
It is time to improve the diagnostic workup of oropharyngeal cancer with circulating tumor HPV DNA: Systematic review and meta‐analysis
Authors: Paolini Francesca , Campo Flaminia , Iocca Oreste , Manciocco Valentina , De Virgilio Armando , De Pascale Valentina , Moretto Silvia , Dalfino Gianluca , Vidiri Antonello , Blandino Giovanni , Pimpinelli Fulvia , Venuti Aldo , Pellini Raul 
Published: September 2023

AbstractThe possibility of detecting circulating tumor HPV DNA (ctHPVDNA) in plasma in patients with oropharyngeal cancer has been demonstrated in several reports. However, these data are from small cohorts and available tests for detection of ctHPVDNA are not fully validated. The aim is to evaluate sensitivity, specificity, and accuracy of ctHPVDNA by ddPCR to define its efficacy in the clinical setting for the diagnosis of HPV + OPSCC. A comprehensive search of three different databases: MEDLINE, Embase, and Cochrane Library databases. A total of 998 patients were evaluated from the 13 studies. OPSSC p16+ were 729, while controls p16− were 269. The meta‐analytic study estimated the diagnostic performance of ctHPVDNA as follows: pooled sensitivity and specificity of 0.90 (95% CI: 0.82–0.94) and 0.94 (95% CI: 0.85–0.98), respectively; positive and negative likelihood ratios of 12.6 (95% CI: 4.9–32.1) and 0.05 (95% CI: 0.02–0.13), respectively. ddPCR for ctHPVDNA has good accuracy, sensitivity, and specificity for diagnosis of HPV + OPSCC. ctHPVDNA kinetic represents a great reliable opportunity to improve diagnostic and therapeutic management of cancer patients and could open new perspectives for understanding tumor biology.
A systematic review of the association between job insecurity and work‐related musculoskeletal disorders
Authors: Mateos‐Gonzalez Laura , Rodríguez‐Suárez Julio , Llosa José Antonio 
Published: September 2023

AbstractA number of studies analyze the link between the presence of psychosocial risk factors and work‐related musculoskeletal disorders. The increase in job insecurity (JI) has resulted in a growing focus on its likely role as a risk factor within occupational health. Accordingly, the aim of this research was to carry out a systematic review of studies that include JI among the relevant risk factors, specifically drawing data from this variable to observe the significance of its association with musculoskeletal disorders (MSDs). For this purpose, a literature search was carried out: from a sample of 859 studies found and 23 were selected after applying the eligibility criteria. Fifteen studies (65.2% of the selection) presented statistically significant results regarding the link between JI and MSDs: the upper limbs and back were the body areas most affected by this association. In sum, JI should be considered a potential precursor of MSDs. Therefore, further study on this psychosocial risk and its association with these types of pathologies is necessary.
Esophageal squamous papilloma: Literature review and case–control retrospective study with histopathological exam of human papillomavirus
Authors: Ahmad Akram I , Lee Arielle , Nithagon Pichayut , Ayaz Omair , Altork Nadera , Peppas Spyros , Alzraikat Sayel , Ayoubi Reza , Smith Andrew , Dhanjal Rachna , Jassal Ajay , Rizzo Samantha M , Cho Won Kyoo 
Published: September 2023

AbstractBackground and AimEsophageal squamous papilloma (ESP) is a benign growth in the esophagus with unknown malignant potential. The mechanism underlying ESP formation is unknown, but human papillomavirus (HPV) infection has been proposed as a potential etiology. We sought to investigate the clinical characteristic of ESP in our population, review the current literature, and highlight the role of HPV.MethodsThis is a retrospective case–control study conducted at two referral centers. We selected the ESP population by free‐text search in the pathology department database and selected controls randomly from the general endoscopy population. Immunostains were used to evaluate ESP tissue for HPV.ResultsBetween January 2016 and December 2021, we identified 66 patients with ESP, with a prevalence of 0.72%. ESP patients were younger, with a median age of 52 years (P = 0.021), and more likely African American (34.4 vs 7.5%, P < 0.001) compared to controls. On endoscopy images, the growth was predominantly solitary (92.5%) in the middle of the esophagus (39.4%), with sizes ranging from 0.2 to 2.3 cm. A total of 62 patients had available tissue for HPV immune staining, and none tested positive for HPV. Eighteen patients had a follow‐up endoscopy with an average of 504.5 days follow‐up period. One patient developed esophageal squamous cell carcinoma during follow‐up.ConclusionsWe observed a higher prevalence of ESP compared to previous studies. The formation of ESP is multifactorial and partially explained by HPV infection in selected populations. The malignant potential of ESP is low but not negligible.
Clinical Significance of Background Parenchymal Enhancement in Breast Cancer Risk Stratification
Authors: Murakami Wakana , Mortazavi Shabnam , Yu Tiffany , Kathuria‐Prakash Nikhita , Yan Ran , Fischer Cheryce , McCann Kelly E. , Lee‐Felker Stephanie , Sung Kyunghyun 
Published: September 2023

BackgroundBackground parenchymal enhancement (BPE) is an established breast cancer risk factor. However, the relationship between BPE levels and breast cancer risk stratification remains unclear.PurposeTo evaluate the clinical relationship between BPE levels and breast cancer risk with covariate adjustments for age, ethnicity, and hormonal status.Study TypeRetrospective.Population954 screening breast MRI datasets representing 721 women divided into four cohorts: women with pathogenic germline breast cancer (BRCA) mutations (Group 1, N = 211), women with non‐BRCA germline mutations (Group 2, N = 60), women without high‐risk germline mutations but with a lifetime breast cancer risk of ≥20% using the Tyrer‐Cuzick model (Group 3, N = 362), and women with <20% lifetime risk (Group 4, N = 88).Field Strength/Sequence3 T/axial non‐fat‐saturated T1, short tau inversion recovery, fat‐saturated pre‐contrast, and post‐contrast T1‐weighted images.AssessmentData on age, body mass index, ethnicity, menopausal status, genetic predisposition, and hormonal therapy use were collected. BPE levels were evaluated by two breast fellowship‐trained radiologists independently in accordance with BI‐RADS, with a third breast fellowship‐trained radiologist resolving any discordance.Statistical TestsPropensity score matching (PSM) was utilized to adjust covariates, including age, ethnicity, menopausal status, hormonal treatments, and prior bilateral oophorectomy. The Mann–Whitney U test, chi‐squared test, and univariate and multiple logistic regression analysis were performed, with an odds ratio (OR) and corresponding 95% confidence interval. Weighted Kappa statistic was used to assess inter‐reader variation. A P value <0.05 indicated a significant result.ResultsIn the assessment of BPE, there was substantial agreement between the two interpreting radiologists (κ = 0.74). Patient demographics were not significantly different between patient groups after PSM. The BPE of Group 1 was significantly lower than that of Group 4 and Group 3 among premenopausal women. In estimating the BPE level, the OR of gene mutations was 0.35.Data ConclusionAdjusting for potential confounders, the BPE level of premenopausal women with BRCA mutations was significantly lower than that of non‐high‐risk women.Level of Evidence3Technical EfficacyStage 3
Diversity in the quasi‐biweekly oscillation sources of the daily maximum temperature over South China during summer
Authors: Li Xiaoqi , Chen Ruidan 
Published: September 2023

AbstractThe summer daily maximum temperature (Tmax) over South China features obvious quasi‐biweekly oscillation (QBWO) and its QBWO sources mainly include three types. The first type is influenced by tropical and mid–high‐latitude antiphase coupling QBWO. Successive suppressed and enhanced convection, accompanying with anticyclonic and cyclonic anomalies, propagate northward from the northwest of the Philippines to South China. At the peak warm phase, an anomalous high dominates over South China and causes significant warming. Meanwhile, an anomalous low associated with a southeastward‐propagating wave train occurs to the north and leading to abnormal cooling in situ. The second type originates from the mid–high latitudes. Before the warm phase, an anomalous high around the Ural Mountains triggers two wave trains propagating southeastward along the great circle route and eastward along the westerly jet, respectively, favouring an anomalous high over North–Northeast China. At the peak warm phase, the anomalous high extends southward, causing significant warming over South–Central China. The third type is influenced by tropical and mid–high‐latitude in‐phase coupling QBWO. The tropical anomalies are similar to the first type but the convection anomalies are centred to the northeast of the Philippines and propagate northwestward. The mid–high‐latitude wave trains are similar to the second type but with relatively weaker southeastward‐propagating wave train. At the peak warm phase, the anomalous highs from the Tropics and mid–high latitudes together dominate a large meridional scope and induce wide‐range warming over eastern China. Intrinsically, the QBWO of the convection north of the Philippines and mid–high‐latitude wave trains are important signals of the atmospheric variability and might be applied to the forecast of South China Tmax.
Influence of Cooling Rate on the Temperature Rising Elution Fractionation of One Poly(1‐butene‐co‐ethylene) Resin and Microstructure of Its Fractions
Authors: Zhang Zhenkang , Xue Yanhu , Li Rui , Liu Wei , He Shuang , Ji Xiangling 
Published: September 2023

AbstractTREF (temperature rising elution fractionation) is a method to separate resins based on crystallizability. The influence of TREF cooling rate (V0) on the fractionation process is still unclear. Herein, a poly(1‐butene‐co‐ethylene) resin is fractionated by the TREF method at three different cooling rates (1, 2, and 4 °C h−1), and then the fractions are analyzed by high‐temperature gel permeation chromatography (HT‐GPC), differential scanning calorimetry (DSC), and 13C‐nuclear magnetic resonance spectroscopy (13C‐NMR). The cooling rate V0 affects the crystallization process of the PB‐1 resin, resulting in different fraction contents at the same elution temperature. Furthermore, the cooling rate also affects the chain microstructure of fractions obtained from the same elution temperatures, i.e., the content of 1‐butene and ethylene monomer units, average sequence length and isotacticity. The lower cooling rate is beneficial to the effective separation of the fractions with weak crystallizability. These results have important guidance for optimizing fractionation conditions and obtaining different narrow distribution fractions of poly(1‐butene) (PB‐1) resin.
Deciphering consumer commitment: Exploring the dual influence of self‐brand and self‐group relationships
Authors: Bauer Brittney C. , Carlson Brad D. , Arnold Mark J. 
Published: September 2023

AbstractConsumer‐brand relationships are highly valued as brand‐committed consumers are thought to deliver many positive outcomes for affiliated brands. However, in addition to connections between individuals and brands, consumer‐brand relationships also involve relationships between individuals and other brand users. Little attention has been given to the potential consequences associated with commitment to other brand users as compared to the brand itself. Therefore, our framework establishes two distinct types of consumer‐brand relationships (i.e., self‐brand relationships vs. self‐group relationships) that differentially influence brand commitment versus group commitment, leading to contrasting effects on both desirable and undesirable brand outcomes. Specifically, our studies illuminate that while brand commitment is largely associated with favorable brand‐related outcomes, group commitment does not protect against brand switching and is negatively related to willingness to pay price premiums and positive word‐of‐mouth. Our main contribution is uncovering how consumer‐brand relationships face tradeoffs between brand and group attachments, whereby commitment provides both conditional benefits as well as unintended consequences.
The impact of service robots on customer satisfaction online ratings: The moderating effects of rapport and contextual review factors
Authors: Borghi Matteo , Mariani Marcello M. , Vega Rodrigo P. , Wirtz Jochen 
Published: September 2023

AbstractRecent research has established a positive relationship between the use of service robots powered by artificial intelligence in hospitality firms and customer satisfaction online ratings, a particularly important form of electronic word of mouth. However, it is not clear if and how this relationship is augmented or diminished by moderating factors. In this study, we examined four potential moderators by using machine learning and natural language processing techniques to analyze 20,166 online reviews of hotels that had implemented service robots. We had four key findings. First, a positive service robot‐satisfaction rating relationship was further enhanced by improved customer‐service robot rapport during the service encounter. Second, higher customer effort focused on service robots in a review reduced the service robot‐satisfaction rating relationship. Third, posting reviews using a mobile device (vs. other devices) showed higher satisfaction ratings. Finally, customers' prior experience in writing online reviews was unrelated to the service robot‐satisfaction rating relationship. Taken together, these results suggest that service robots should be designed to be interactive and encourage customers to build rapport, for example, by service robots engaging in conversational flows. Moreover, customers should be nudged to use their mobile devices to post timely reviews on their positive human–robot interactions.
Mutations in CFAP47, a previously reported MMAF causative gene, also contribute to the respiratory defects in patients with PCD
Authors: Ge Haijun , Zhou Wangji , He Miao , Zheng Haixia , Zhao Xinyue , Zhang Ting , Zhang Ying , Shao Chi , Cheng Chongsheng , Liu Yaping , Tian Xinlun , Xu Kai‐Feng , Zhang Xue 
Published: September 2023

AbstractBackgroundPrimary ciliary dyskinesia (PCD) is a genetic ciliopathy characterized by dysfunction of motile cilia. Currently, approximately 50 causative genes accounting for 60%–70% of all PCD cases have been identified in PCD‐affected individuals, but the etiology in approximately 30%–40% of PCD cases remains unknown.MethodsWe analyzed the clinical and genetic data of two PCD individuals who were suspected of having PCD. Whole‐exome sequencing and Sanger sequencing were performed to identify and verify the variants in CFAP47. We also evaluated the expression of CFAP47 by real‐time quantitative PCR and immunofluorescence. Transmission electron microscopy in respiratory epithelial cells was also conducted to analyze ciliary function.ResultsTwo hemizygous missense variants of X‐linked CFAP47 in two unrelated PCD individuals were identified. The expression of CFAP47 in two PCD individuals was significantly reduced in vivo and in vitro assays. A reduction in the amount of epithelial ciliary cells and basal bodies from PCD individuals was also observed.ConclusionsWe describe two hemizygous missense variants of X‐linked CFAP47 in two unrelated PCD individuals and prove CFAP47 variants are related to a reduced number of epithelial ciliary cells. Therefore, we suggest that CFAP47 should be known as a novel pathogenic gene of human PCD.
Miniaturized Q‐band ×8 frequency multiplier with optimized efficiency in 65‐nm CMOS technology
Authors: Lim Jeong‐Taek , Oh Hyun‐Myung , Kim Jae‐Sun , Choi Han‐Woong , Lee Kyeong‐Hyeok , Kim Choul‐Young 
Published: September 2023

AbstractIn this work, a miniaturized Q‐band ×8 frequency multiplier with a structure designed for optimized efficiency is demonstrated. The circuit is fabricated using 65‐nm CMOS technology and designed to operate from 46.4 to 50.4 GHz. The ×8 frequency multiplier consists of three doublers and three amplifiers for the optimization of efficiency and low‐input power. Three doublers are designed using balanced topology for high harmonic suppression. The transformer balun is conjoined as an input balun in the frequency doubler and load inductor in amplifier. The transformer balun used between the first amplifier and first doubler, and between the second amplifier and third doubler to achieve compact size. This ×8 frequency multiplier achieves a maximum output power of −1.9 dBm with an input power of −24 dBm, and harmonic suppressions are over 32.5 dBc between 46.4 and 50 GHz. The ×8 frequency multiplier consumes a maximum power of 50 mW and occupies area of 0.92 mm2.