bluuebunny/crossref_metadata_2025_split huggingface dataset:
Late Miocene to recent tectonic evolution of the Macquarie Triple Junction
Authors: Gasperini Luca , Ligi Marco , Accettella Daniela , Bosman Alessandro , Cuffaro Marco , Lodolo Emanuele , Martorelli Eleonora , Muccini Filippo , Palmiotto Camilla , Polonia Alina 
Published: December 2022

AbstractThe Pacific, Antarctic, and Macquarie lithospheric plates diverge from the Macquarie Triple Junction (MTJ) in the southwestern Pacific Ocean, south of Macquarie Island. Morphobathymetric, magnetic, and gravity data have been used to understand the evolution of the three accretionary/transform boundaries that meet at the MTJ. Plate velocities, estimated near the MTJ and averaged over the past 3 m.y., indicate an unstable ridge–fault–fault triple junction. The long life (&gt;6 m.y.) of this configuration can be attributed to a rapid increase in spreading asymmetry along the Southeast Indian Ridge segment as it approaches the MTJ, and to transtension along the southernmost strand of the Macquarie–Pacific transform boundary. A major change in plate motion triggered the development of the Macquarie plate at ca. 6 Ma and makes clear the recent evolution of the MTJ, including (1) shortening of the Southeast Indian Ridge segment; (2) formation of the westernmost Pacific-Antarctic Ridge, which increased its length over time; and (3) lengthening of the two transform boundaries converging in the MTJ. The clockwise change of the Pacific-Antarctic motion (ca. 12–10 Ma) led to complex geodynamic evolution of the plate boundary to the east of the triple junction, with fragmentation of the long-offset Emerald transform fault and its replacement over a short time interval (1–2 m.y.) with closely spaced, highly variable transform offsets that were joined by short ridge segments with time-varying asymmetries in the spreading rates.
Endovascular therapy for acute ischemic stroke with distal medium vessel occlusion: a systematic review and meta-analysis
Authors: Loh Enver De Wei , Toh Keith Zhi Xian , Kwok Gabriel Yi Ren , Teo Yao Hao , Teo Yao Neng , Goh Claire , Syn Nicholas L , Ho Andrew Fu-Wah , Sia Ching-Hui , Sharma Vijay Kumar , Tan Benjamin YQ , Yeo Leonard LL 
Published: December 2022

AimsEndovascular therapy (EVT) for distal medium vessel occlusions (DMVOs) is a potential frontier of acute ischemic stroke (AIS) treatment, but its efficacy against best medical therapy (BMT) remains unknown. We performed a systematic review and meta-analysis evaluating the efficacy and safety of EVT versus BMT in primary DMVO.MethodsWe systematically searched PubMed, Cochrane Library and Embase, from inception to August 14, 2022, for studies comparing EVT with BMT in DMVO-AIS. We adopted the Distal Thrombectomy Summit Group’s definition of DMVO. Efficacy outcomes were functional independence (90-day modified Rankin Scale (mRS) 0–2) and excellent functional outcomes (90-day mRS 0–1). Safety outcomes were symptomatic intracranial hemorrhage (sICH) and 90-day mortality.ResultsFourteen observational and two randomized-controlled studies were included, with 1202 patients receiving EVT and 1267 receiving BMT. After trim-and-fill correction, EVT achieved significantly better odds of functional independence than BMT (adjusted OR 1.61, 95% CI 1.06 to 2.43). There were no significant differences in overall excellent functional outcomes (OR 1.23, 95% CI 0.88 to 1.71), sICH (OR 1.44, 95% CI 0.78 to 2.66), and mortality (OR 1.03, 95% CI 0.73 to 1.45). Stratified by EVT method, mechanical thrombectomy±intra-arterial thrombolysis achieved more excellent functional outcomes than BMT (OR 1.59, 95% CI 1.13 to 2.23). In mild strokes (National Institutes of Health Stroke Scale score <6), EVT caused significantly more sICH (OR 6.30, 95% CI 1.55 to 25.64).ConclusionsEVT shows promising efficacy benefit over BMT for primary DMVO-AIS. Further randomized controlled trials are necessary to evaluate the efficacy and safety of EVT in DMVO-AIS.
Bavarian: Betweenness Centrality Approximation with Variance-aware Rademacher Averages
Authors: Cousins Cyrus , Wohlgemuth Chloe , Riondato Matteo 
Published: December 2022

“[A]llain Gersten, Hopfen, und Wasser”— 1516 ReinheitsgebotWe presentBavarian, a collection of sampling-based algorithms for approximating the Betweenness Centrality (BC) of all vertices in a graph. Our algorithms use Monte-Carlo Empirical Rademacher Averages (MCERAs), a concept from statistical learning theory, to efficiently compute tight bounds on the maximum deviation of the estimates from the exact values. The MCERAs provide a sample-dependent approximation guarantee much stronger than the state-of-the-art, thanks to its use of variance-aware probabilistic tail bounds. The flexibility of the MCERAs allows us to introduce a unifying framework that can be instantiated with existing sampling-based estimators of BC, thus allowing a fair comparison between them, decoupled from the sample-complexity results with which they were originally introduced. Additionally, we prove novel sample-complexity results showing that, for all estimators, the sample size sufficient to achieve a desired approximation guarantee depends on the vertex-diameter of the graph, an easy-to-bound characteristic quantity. We also show progressive-sampling algorithms and extensions to other centrality measures, such as percolation centrality. Our extensive experimental evaluation ofBavarianshows the improvement over the state-of-the-art made possible by the MCERAs (2–4× reduction in the error bound), and it allows us to assess the different trade-offs between sample size and accuracy guarantees offered by the different estimators.
Examination of Sexual Identity Differences in the Prevalence of Hypertension and Antihypertensive Medication Use Among US Adults: Findings From the Behavioral Risk Factor Surveillance System
Authors: Sharma Yashika , Bhargava Anisha , Doan Danny , Caceres Billy A. 
Published: December 2022

Background:
Recent evidence suggests that sexual minority (eg, gay/lesbian, bisexual) adults might be at increased risk of hypertension compared with heterosexual adults. However, disparities by sexual identity in antihypertensive medication use among adults with hypertension have not been comprehensively examined.

Methods:
We analyzed data from the Behavioral Risk Factor Surveillance System (2015–2019), to examine sexual identity differences in the prevalence of hypertension and antihypertensive medication use among adults. We ran sex-stratified logistic regression models to estimate the odds ratios of diagnosis of hypertension and antihypertensive medication use among sexual minority (ie, gay/lesbian, bisexual, and other) and heterosexual adults (reference group).

Results:
The sample included 420 340 participants with a mean age of 49.7 (±17.0) years, of which 66.7% were Non-Hispanic White. Compared with heterosexual participants of the same sex, bisexual women (adjusted odds ratio, 1.19 [95% CI, 1.03–1.37]) and gay men (adjusted odds ratio, 1.18 [95% CI, 1.03–1.35]) were more likely to report having been diagnosed with hypertension. Among women with diagnosed hypertension, bisexual women had lower odds of current antihypertensive medication use (adjusted odds ratio, 0.71 [95% CI, 0.56–0.90]). Among men with diagnosed hypertension, gay men were more likely than heterosexual men to report current antihypertensive medication use (adjusted odds ratio, 1.39 [95% CI, 1.10–1.78]). Compared with heterosexual participants of the same sex, there were no differences in hypertension or antihypertensive medication use among lesbian women, bisexual men, and participants who reported their sexual identity as other.

Conclusions:
Clinical and public health interventions are needed to reduce the risk of hypertension among bisexual women and gay men. Bisexual women were at higher risk of untreated hypertension, which may be attributed to lower health care utilization due to fear of discrimination from health care providers and socioeconomic disadvantage. Future research is needed to better understand factors that may contribute to untreated hypertension among bisexual women with hypertension.
Decision for tPA Administration, Not Response Time, Contributes Most to Variation in Thrombolysis Times Onboard Mobile Stroke Unit
Authors: Akkipeddi Sajal Medha K. , Ellens Nathaniel R. , Schartz Derrek , Rahmani Redi , Burgett Jason L. , Proper Diana , Pilcher Webster H. , Kelly Adam G. , Benesch Curt G. , Cushman Jeremy T. , Mattingly Thomas K. , Bhalla Tarun , Bender Matthew T. 
Published: December 2022

Background
Hospitals have improved stroke thrombolysis times through rigorous assessment of care delays. However, this same rigor has not yet been applied to the novel setting of mobile stroke units (MSUs).

Methods
We reviewed all cases of intravenous tPA (tissue‐type plasminogen activator) administration onboard our MSU in Rochester, NY, since its first complete year of operation in 2019. The dispatch timeline was divided into 6 intervals: (1) response time, (2) onboarding time, (3) head computed tomography collection, (4) head computed tomography reading, (5) decision time, and (6) intravenous tPA administration.

Results

The mean±SD total time between MSU dispatch and tPA was 42±8.4 minutes (range, 26–60 minutes; N=53). The largest mean duration was in (1), between dispatch and arrival (12.0±4.7 minutes). However, the intercase variation was greatest in (5), between head computed tomography reading and treatment decision (6.3±6.2 minutes). After ranking cases by total time, the mean decision times of first and fourth quartile cases varied the most, by a factor of 2.45, whereas the mean times for the other intervals varied by <1.50. Decision time was the interval most closely correlated with the mean total time (Spearman ρ=0.46;
P
=0.00051), which significantly decreased from 2019 to 2020 (Mann‐Whitney, Z=2.38;
P
=0.02). Decision time was negatively correlated with time since inception of the MSU (Spearman ρ=−0.29;
P
=0.037; Figure 2B), suggesting that decision time drove both variations and improvements in overall thrombolysis time.

Conclusions
The primary driver of variation in total time from emergency alert to tPA administration is provider decision time in our MSU program in Rochester, NY. This observation should be investigated in other settings but may ultimately inform MSU training and staffing to optimize MSU treatment timelines.
From Word Types to Tokens and Back: A Survey of Approaches to Word Meaning Representation and Interpretation
Authors: Apidianaki Marianna 
Published: December 2022

Abstract
Vector-based word representation paradigms situate lexical meaning at different levels of abstraction. Distributional and static embedding models generate a single vector per word type, which is an aggregate across the instances of the word in a corpus. Contextual language models, on the contrary, directly capture the meaning of individual word instances. The goal of this survey is to provide an overview of word meaning representation methods, and of the strategies that have been proposed for improving the quality of the generated vectors. These often involve injecting external knowledge about lexical semantic relationships, or refining the vectors to describe different senses. The survey also covers recent approaches for obtaining word type-level representations from token-level ones, and for combining static and contextualized representations. Special focus is given to probing and interpretation studies aimed at discovering the lexical semantic knowledge that is encoded in contextualized representations. The challenges posed by this exploration have motivated the interest towards static embedding derivation from contextualized embeddings, and for methods aimed at improving the similarity estimates that can be drawn from the space of contextual language models.
Picturing the Tetragrammaton: Moses Cordovero’s Pardes Rimonim from Manuscript to Digital Form
Authors: Matanky Eugene D. 
Published: December 2022

Abstract
This article explores the transformation of the divine word/image—the graphic representation of the Tetragrammaton—that originated in the work of Joseph Hamadan, a thirteenth-century kabbalist, and was incorporated into the work of Moses Cordovero, a sixteenth-century kabbalist. The issue of the divine word/image is an intersection of various theological positions found in kabbalistic thought concerning the corporeality of the divine through the medium of the word. However, alongside the theological positions are technological capabilities. This article demonstrates how various actors—kabbalists, copyists, printers, and even modern-day digital pirates—changed this word/image, intentionally and unintentionally, through their application of their technical skills and technological abilities. This article also raises a methodological point concerning the study of image-laden Jewish texts in our digital age.
“Perhaps The Oldest Piece of Ecclesiastical Furniture in this Country”: The Construction and Destruction of Solomon Schechter’s Cairo Genizah Torah Ark
Authors: Selis David 
Published: December 2022

Abstract
In 1897, Solomon Schechter brought a hoard of Hebrew manuscripts, now known collectively as the Cairo Genizah, to England from Cairo. Along with these manuscripts were several wooden Hebrew inscription fragments from Cairo’s Ben Ezra Synagogue. When Schechter left Cambridge to assume the presidency of the Jewish Theological Seminary of America, these fragments were brought to New York where they were transformed into a Torah Ark. This Torah ark was used at the Seminary for three decades and subsequently exhibited at the Jewish Museum, New York and The Metropolitan Museum of Art. It was featured on numerous postcards and in major works on Jewish art. In 1997, it was deconstructed by the Jewish Museum to extract the medieval inscriptions. This article explores the history, meaning and reception of the Schechter Torah Ark as a window into the complexities of Schechter’s legacy and the history of Jewish scholarship in the twentieth century.
Escalation from intra-aortic balloon pump to axillary impella 5.5 support: Staged removal of the femoral access
Authors: Sosa Carlos Vazquez , Ohira Suguru , Ahmad Hasan , Isath Ameesh , De La Pena Corazon , Spielvogel David , Kai Masashi 
Published: December 2022

Background: With the growing population of advanced heart failure, the use of Impella 5.5 has been increasing. Here, we report an effective strategy of removing the intra-aortic balloon pump (IABP) in the setting of escalation of support to Impella 5.5. Results: From January 1, 2022 to June 30, 2022, a total of 6 patients have undergone IABP removal during Impella 5.5 insertion. The IABP was subsequently removed over the long wire with manual compression on the femoral artery to control bleeding. An 8 or 9 Fr short sheath is inserted over the wire. Staged hemostasis was successfully performed in 4 patients, and the remaining two patients required escalation of support to veno-arterial membrane oxygenation as EC-PELLA utilizing the femoral arterial sheath. Conclusion: This does not only achieve secured hemostasis but also enables a smooth transition to further escalate support such as extracorporeal membrane oxygenation support, if necessary.
Interventions to reduce loss to follow up in common retinal pathology: A systematic review
Authors: Muste Justin C , Russell Matthew W , Iyer Amogh I , Singh Rishi P 
Published: December 2022

Purpose Loss to follow-up or fragmented follow-up episodes (LTFU) may contribute to suboptimal clinical outcomes, especially when comparing real world data to clinical trials. This systemic review gathers available evidence around interventions meant to decrease the LTFU in AMD, RVO, and DME patients Patients and methods PubMed was queried using a literature search strategy and reviewed by the authors. Studies with interventions aimed at reducing lost to follow up were included. Results Ten studies were extracted from 89 candidate publications. Discussion Telephone interventions featuring assistance in scheduling in improving LTFU in urban, African American populations over 50 years old with diabetic retinopathy. The same interventions have shown promise in glaucoma, but remain understudied in AMD, RVO, and other geographic, ethnic, and socioeconomic demographics. Conclusion No sole intervention with efficacy in improving LTFU has been developed. A standardized definition of LTFU, as well as testing interventions across broad age, geography, ethnic, racial, and socioeconomic lines. Longitudinal data would also add credence to the efficacy of purported interventions. Other No sources of funding for this article.
Association of paramagnetic rim lesions and retinal layer thickness in patients with multiple sclerosis
Authors: Krajnc Nik , Dal-Bianco Assunta , Leutmezer Fritz , Kasprian Gregor , Pemp Berthold , Kornek Barbara , Berger Thomas , Rommer Paulus Stefan , Hametner Simon , Lassmann Hans , Bsteh Gabriel 
Published: December 2022

Background: Paramagnetic rim lesions (PRLs) are chronic active lesions associated with a more severe disease course in multiple sclerosis (MS). Retinal layer thinning measured by optical coherence tomography (OCT) is a biomarker of neuroaxonal damage associated with disability progression in MS. Objective: We aimed to determine a potential association between OCT parameters (peripapillary retinal nerve fiber layer (pRNFL) ganglion cell-inner plexiform layer (GCIPL), inner nuclear layer (INL) thickness), and PRLs in patients with MS (pwMS). Methods: In this cross-sectional retrospective study, we included pwMS with both 3T brain MRI and an OCT scan. Regression models were calculated with OCT parameters (pRNFL, GCIPL, INL) as dependent variables, and the number of PRLs as an independent variable adjusted for covariates. Results: We analyzed data from 107 pwMS (mean age 34.7 years (SD 10.9), 64.5% female, median disease duration 6 years (IQR 1–13), median EDSS 1.5 (range 0–6.5)). Higher number of PRLs was associated with lower pRNFL (β = −0.18; 95% CI −0.98, −0.03; p = 0.038) and GCIPL thickness (β = −0.21; 95% CI −0.58, −0.02; p = 0.039). Conclusion: The association between higher number of PRLs and lower pRNFL and GCIPL thicknesses provides additional evidence that pwMS with PRLs are affected by a more pronounced neurodegenerative process.
New Graduate Nurses’ Incivility Experiences: The Roles of Workplace Empowerment, Nursing Leadership and Areas of Worklife
Authors: Blackstock Sheila , Cummings Greta G. , Glanfield Florence , Yonge Olive 
Published: December 2022

Aims To determine what extent are workplace empowerment, New Graduate Nurses’ (NGN) perceptions of nurse leaders, trust in management, and areas of worklife predict coworker incivility experiences? Background NGNs’ perceptions of nursing leaderships’ control over workload contribute to coworker incivility experiences were tested. The relationship between workplace empowerment, authentic leadership, and areas of work life (workload control and fair resource allocation) to coworker incivility experiences were examined. Design Secondary analysis of Starting Out, national survey, Time 1 dataset. Select factors of workplace empowerment, authentic leadership, areas of worklife, trust in management and NGNs’ co- worker incivility experiences were situated within an ecological approach. Multiple linear regression was used to test whether a negative relationship of workplace empowerment, areas of worklife and authentic leadership to NGNs co-worker incivility experiences and important new findings were discovered. Results First, NGNs’ perceptions of workplace empowerment predict coworker incivility experiences when controlling for authentic leadership and trust in management. Second, NGNs’ perceptions of areas of worklife predict coworker incivility experiences when controlling for authentic leadership, trust in management, and workplace empowerment. Third, NGNs’ perceptions of authentic leadership do not predict coworker incivility experiences when controlling for workplace empowerment and trust in management. Finally, NGNs’ perceptions of authentic leadership do predict coworker incivility experiences when trust in management and workplace empowerment are not controlled. Conclusions NGNs’ perceptions of authentic leadership would benefit from workplace empowerment of the nurse leader in workplace environments to mitigate coworker incivility experiences.
Green composites from vanillin-based benzoxazine and silane surface modified chopped carbon fibers
Authors: Derradji Mehdi , Khiari Karim , Mehelli Oussama , Abdous Slimane , Amri Bouchra , Belgacemi Raouf , Ramdani Noureddine , Zegaoui Abdeljalil , Liu Wenbin 
Published: December 2022

By following the rules of green chemistry, a novel composite is developed from a renewable and ecofriendly resource, namely, vanillin. The latter was used as a phenolic precursor for the microwave synthesis of a bio-based benzoxazine resin (Va-BZ). Afterward, high-performance green composites were developed by reinforcing Va-BZ with various amounts of chopped silane surface modified carbon fibers (CFs). The chemical structure of the Va-BZ monomers was confirmed by 1H NMR and Fourier transform infrared spectroscopy. The grafting of the silane moiety on the CF surface was assessed by FTIR and TGA analyses. The autocatalytic ring opening polymerization of the Va-BZ monomers was confirmed by DSC analysis. The mechanical performances of the developed green composites were studied by flexural and tensile investigations. The findings suggested that the maximum amount of 20 wt. CFs afforded the best results, with flexural and tensile strengths of 450 and 462 MPa, respectively. The SEM was used to study the fractured tensile surfaces and elucidated the toughening mechanism. Meanwhile, the TGA showed that the introduction of the CFs markedly improved the thermal stability of the benzoxazine matrix. Overall, this study confirmed that greener approaches can also result in high-performance composites satisfying the needs of exigent applications.
Medicinal cannabis for Australian patients with chronic refractory pain including arthritis
Authors: Schubert Elise A , Johnstone Masego T , Benson Melissa J , Alffenaar Johannes C , Wheate Nial J 
Published: December 2022

Objectives To examine the tolerability and effectiveness of medicinal cannabis prescribed to patients for chronic, refractory pain, with a subset analysis on arthritis. Methods This was an interim analysis of the CA Clinics Observational Study investigating self-reported adverse events (AEs) and changes in health-related quality of life (HRQoL) outcomes over time after commencing medicinal cannabis. Patients were prescribed medicinal cannabis by a medical practitioner, containing various ratios of Δ9-tetrahydrocannabinol (THC) and/or cannabidiol (CBD). Results The overall chronic pain cohort, and specifically the balanced CBD:THC products, were associated with significantly reduced pain intensity scores ( p = 0.003, p = 0.025), with 22% of patients reporting a clinically meaningful reduction in pain intensity. Patients in the arthritis subset ( n = 199) reported significantly reduced pain intensity scores ( p = 0.005) overall, and specifically for those taking CBD-only ( p = 0.018) and balanced products ( p = 0.005). Other HRQoL outcomes, including pain interference and pain impact scores were significantly improved depending on the CBD:THC ratio. Products that contained a balanced ratio of CBD:THC were associated with improvements in the most number of PROMIS-29 domains. Approximately half ( n = 364; 51%) of the chronic pain cohort experienced at least one AE, the most common being dry mouth (24%), somnolence (19%) or fatigue (12%). These findings were similar in the arthritis subset. Discussion Medicinal cannabis was observed to improve pain intensity scores and HRQoL outcomes in patients with chronic, refractory pain, providing real-world insights into medicinal cannabis’ therapeutic potential.