bluuebunny/crossref_metadata_2025_split huggingface dataset:
A VERITAS/Breakthrough Listen Search for Optical Technosignatures
Authors: Acharyya A. , Adams C. B. , Archer A. , Bangale P. , Batista P. , Benbow W. , Brill A. , Capasso M. , Errando M. , Falcone A. , Feng Q. , Finley J. P. , Foote G. M. , Fortson L. , Furniss A. , Griffin S. , Hanlon W. , Hanna D. , Hervet O. , Hinrichs C. E. , Hoang J. , Holder J. , Humensky T. B. , Jin W. , Kaaret P. , Kertzman M. , Kherlakian M. , Kieda D. , Kleiner T. K. , Korzoun N. , Kumar S. , Lang M. J. , Lundy M. , Maier G. , McGrath C. E. , Millard M. J. , Miller H. R. , Millis J. , Mooney C. L. , Moriarty P. , Mukherjee R. , O’Brien S. , Ong R. A. , Pohl M. , Pueschel E. , Quinn J. , Ragan K. , Reynolds P. T. , Ribeiro D. , Roache E. , Ryan J. L. , Sadeh I. , Saha L. , Santander M. , Sembroski G. H. , Shang R. , Tak D. , Talluri A. K. , Tucci J. V. , Vazquez N. , Williams D. A. , Wong S. L. , Woo J. ,   VERITAS Collaboration, DeBoer D. , Isaacson H. , de Pater I. , Price D. C. , Siemion A. 
Published: August 2023

Abstract
The Breakthrough Listen Initiative is conducting a program using multiple telescopes around the world to search for “technosignatures”: artificial transmitters of extraterrestrial origin from beyond our solar system. The Very Energetic Radiation Imaging Telescope Array System (VERITAS) Collaboration joined this program in 2018 and provides the capability to search for one particular technosignature: optical pulses of a few nanoseconds in duration detectable over interstellar distances. We report here on the analysis and results of dedicated VERITAS observations of Breakthrough Listen targets conducted in 2019 and 2020 and of archival VERITAS data collected since 2012. Thirty hours of dedicated observations of 136 targets and 249 archival observations of 140 targets were analyzed and did not reveal any signals consistent with a technosignature. The results are used to place limits on the fraction of stars hosting transmitting civilizations. We also discuss the minimum pulse sensitivity of our observations and present VERITAS observations of CALIOP: a space-based pulsed laser on board the Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations. The detection of these pulses with VERITAS, using the analysis techniques developed for our technosignature search, allows a test of our analysis efficiency and serves as an important proof of principle.
Constraints on Evolutionary Timescales for M Dwarf Planets from Dynamical Stability Arguments
Authors: Teixeira Katie , Ballard Sarah 
Published: August 2023

Abstract
The diversity of dynamical conditions among exoplanets is now well established. Yet, the relevance of orbital dynamical timescales to biological evolutionary timescales is poorly understood. Given that even minor orbital changes may place significant pressure on any organisms living on a planet, dynamical sculpting has important implications for the putative evolution of life. In this manuscript, we employ a Monte Carlo framework to investigate how a range of exoplanetary dynamical sculpting timescales affects timescales for biological evolution. We proceed with minimal assumptions for how dynamical sculpting proceeds and the emergence and persistence of life. We focus our investigation on M dwarf stars, the most common exoplanetary hosts in the Milky Way. We assign dynamical statuses, dependent on stellar age, to a suite of planetary systems, varying the rate of dynamical disruption within limits that are consistent with present-day planet demographics. We then simulate the observed yield of planets according to the completeness of NASA's Kepler and TESS missions, and investigate the properties of these samples. With this simplified approach, we find that systems hosting multiple transiting planets ought to have, on average, shorter dynamically uninterrupted intervals than single-transiting systems. However, depending upon the rate of dynamical sculpting, planets orbiting older stars will exhibit the opposite trend. Even modest constraints on stellar age would help identify older stars for which this holds. The degree of these effects varies, dependent upon both the intrinsic dynamical demographics of exoplanets and whether we consider planets detected by NASA’s Kepler or TESS missions.
Theory and Transport of Nearly Incompressible Magnetohydrodynamic Turbulence: High Plasma Beta Regime
Authors: Adhikari Laxman , Zank Gary P. , Wang Bingbing , Zhao Lingling , Telloni Daniele , Pitna Alex , Opher Merav , Shrestha Bishwas , McComas David J. , Nykyri Katariina 
Published: August 2023

Abstract
Nearly incompressible magnetohydrodynamic (NI MHD) theory for β ∼ 1 (or β ≪ 1) plasma has been developed and applied to the study of solar wind turbulence. The leading-order term in β ∼ 1 or β ≪ 1 plasma describes the majority of 2D turbulence, while the higher-order term describes the minority of slab turbulence. Here, we develop new NI MHD turbulence transport model equations in the high plasma beta regime. The leading-order term in a β ≫ 1 plasma is fully incompressible and admits both structures (flux ropes or magnetic islands) and slab (Alfvén waves) fluctuations. This paper couples the NI MHD turbulence transport equations with three fluid (proton, electron, and pickup ion) equations, and solves the 1D steady-state equations from 1–75 au. The model is tested against 27 yr of Voyager 2 data, and Ulysses and NH SWAP data. The results agree remarkably well, with some scatter, about the theoretical predictions.
Circumgalactic Medium on the Largest Scales: Detecting X-Ray Absorption Lines with Large-area Microcalorimeters
Authors: Bogdán Ákos , Khabibullin Ildar , Kovács Orsolya E. , Schellenberger Gerrit , ZuHone John , Burchett Joseph N. , Dolag Klaus , Churazov Eugene , Forman William R. , Jones Christine , Kilbourne Caroline , Kraft Ralph P. , Lau Erwin , Markevitch Maxim , McCammon Dan , Nagai Daisuke , Nelson Dylan , Ogorzalek Anna , Oppenheimer Benjamin D. , Sarkar Arnab , Su Yuanyuan , Truong Nhut , Veilleux Sylvain , Vladutescu-Zopp Stephan , Zhuravleva Irina 
Published: August 2023

Abstract
The circumgalactic medium (CGM) plays a crucial role in galaxy evolution as it fuels star formation, retains metals ejected from the galaxies, and hosts gas flows in and out of galaxies. For Milky Way–type and more-massive galaxies, the bulk of the CGM is in hot phases best accessible at X-ray wavelengths. However, our understanding of the CGM remains largely unconstrained due to its tenuous nature. A promising way to probe the CGM is via X-ray absorption studies. Traditional absorption studies utilize bright background quasars, but this method probes the CGM in a pencil beam, and, due to the rarity of bright quasars, the galaxy population available for study is limited. Large-area, high spectral resolution X-ray microcalorimeters offer a new approach to exploring the CGM in emission and absorption. Here, we demonstrate that the cumulative X-ray emission from cosmic X-ray background sources can probe the CGM in absorption. We construct column density maps of major X-ray ions from the Magneticum simulation and build realistic mock images of nine galaxies to explore the detectability of X-ray absorption lines arising from the large-scale CGM. We conclude that the O VII absorption line is detectable around individual massive galaxies at the 3σ–6σ confidence level. For Milky Way–type galaxies, the O VII and O VIII absorption lines are detectable at the ∼ 6σ and ∼ 3σ levels even beyond the virial radius when coadding data from multiple galaxies. This approach complements emission studies, does not require additional exposures, and will allow for probing the baryon budget and the CGM at the largest scales.
Three-dimensional SPH Simulations of FU Orionis Star Flares in the Clumpy Accretion Model
Authors: Demidova Tatiana V. , Grinin Vladimir P. 
Published: August 2023

Abstract
One of the early hypotheses about the origin of FU Orionis star (FUORs) outbursts explains them based on the fall of gas clumps from the remnants of protostellar clouds onto protoplanetary disks surrounding young stars. To calculate the consequences of such an event, we make 3D hydrodynamic simulations using the smoothed particle hydrodynamics method. It is shown that the fall of the clump on the disk in the vicinity of the star actually causes a burst of the star’s accretion activity, resembling in its characteristics the flares of known FUORs. In the region of incidence, an inhomogeneous gas ring is formed, which is inclined relative to the outer disk. During several revolutions around the star, this ring combines with the inner disk and forms a tilted disk. In the process of evolution, the inner disk expands, and its inclination relative to the outer disk decreases. After 100 revolutions, the angle of inclination is a few degrees. This result is of interest in connection with the discovery in recent years of protoplanetary disks, the inner region of which is inclined relative to the outer one. Such structures are usually associated with the existence in the vicinity of a star of a massive body (planet or brown dwarf), whose orbit is inclined relative to the plane of the disk. The results of our modeling indicate the possibility of an alternative explanation for this phenomenon.
Correction. <i>Spatial cluster analysis of COVID-19 in Malaysia (Mar-Sep, 2020)</i>
Authors: Publisher The 
Published: August 2023

In the Article titled "Spatial cluster analysis of COVID-19 in Malaysia (Mar-Sep, 2020)." published May 5th, 2021, in Vol. 16(1) of Geospatial Health, an author's name was misspelled. The seventh author's name should be "Alamgir".

Reference:
Ullah S, Mohd Nor NH, Daud H, Zainuddin N, Gandapur MS J, Ali I, Khalil A, 2021. Spatial cluster analysis of COVID-19 in Malaysia (Mar-Sep, 2020). Geospatial Health, 16:961. https://doi.org/10.4081/gh.2021.961
Comparison between ocular biometry parameters in patients with unilateral congenital glaucoma
Authors: Chandran Premanand , Sneha Chavan , Subramanian Sunada , Raman Ganesh V 
Published: August 2023

Purpose:
To compare the axial length (AL) and corneal diameter between glaucomatous eye (GE) and fellow normal eye (NE) in patients with unilateral congenital glaucoma and to obtain a normative database for ocular growth among Indian children below 3 years of age.

Methods:
Retrospective longitudinal study. Patients who had a follow-up of 3 years from diagnosis with ocular biometry parameters being recorded at least thrice (once a year) and fellow eye being normal were included. Data collected were age, gender, intraocular pressure (IOP), AL, corneal diameter, optic disc findings, diagnosis, and surgery details.

Results:
Eleven patients were analyzed. All GE underwent combined trabeculotomy with trabeculectomy. Mean (SD) baseline IOP, AL, and corneal diameter were 17.1 (6.7) mmHg, 18.9 (1.1) mm and 12 (0.91) mm in GE, and 11.1 (3.8) mmHg, 17.8 (0.44) mm, and 10.5 (0.58) mm in NE, respectively. Increase in AL was 3.1 mm in the first year followed by 0.6 mm in second year and 0.4 mm in third year in GE compared to 2.6, 0.6, and 0.5 mm in NE, respectively. Corneal diameter increased by 1.1 mm in GE in the first year and remained stable thereafter compared to 0.7 mm in first year followed by 0.3 mm in second year and stable thereafter in NE. The percentage of success was 73% at 3 years.

Conclusion:
Axial length and corneal diameter were higher in GE than NE at all-time points. With prompt intervention, the growth curve of the GE was made parallel to that of NE.
Comparative proteomics of proliferative diabetic retinopathy in people with Type 2 diabetes highlights the role of inflammation, visual transduction, and extracellular matrix pathways
Authors: Sen Sagnik , Udaya Prithviraj , Jeya Maheshwari Jayapal , Kohli Piyush , Parida Haemoglobin , Kannan Naresh Babu , Ramasamy Kim , Dharmalingam Kuppamuthu 
Published: August 2023

Purpose:
To explore the vitreous humor proteome from type 2 diabetes subjects with proliferative diabetic retinopathy (PDR) in the Indian population.

Methods:
We performed mass spectrometry-based label-free quantitative analysis of vitreous proteome of PDR (n = 13) and idiopathic macular hole (IMH; control) subjects (n = 14). Nine samples of PDR and 10 samples of IMH were pooled as case and control, respectively, and compared. Four samples each of PDR and IMH were analyzed individually without pooling to validate the results of the pooled analysis. Comparative quantification was performed using Scaffold software which calculated the fold changes of differential expression. Bioinformatics analysis was performed using DAVID and STRING software.

Results:
We identified 469 proteins in PDR and 517 proteins in IMH vitreous, with an overlap of 172 proteins. Also, 297 unique proteins were identified in PDR and 345 in IMH. In PDR vitreous, 37 proteins were upregulated (P < 0.05) and 19 proteins were downregulated compared to IMH. Protein distribution analysis clearly demonstrated a separation of protein expression in PDR and IMH. Significantly upregulated proteins included fibrinogen gamma chain, fibrinogen beta chain, and carbonic anhydrase 1 and downregulated proteins included alpha-1-antitrypsin, retinol-binding protein 3, neuroserpin, cystatin C, carboxypeptidase E and cathepsin-D.

Conclusion:
Diabetic retinopathy pathogenesis involves proteins which belong to inflammation, visual transduction, and extracellular matrix pathways. Validation-based experiments using enzyme-linked immunosorbent assay (ELISA) or western blotting are needed to establish cause and effect relationships of these proteins to the disease state, to develop them as biomarkers or drug molecules.
A technological approach to “Reaching the Unreached” – Leveraging teleophthalmology services in Rural Gujarat
Authors: Shah Zalak , Shroff Uma , Gajiwala Uday , Shamanna B R 
Published: August 2023

Purpose:
Early detection of sight-threatening disorders by technological applications like teleophthalmology and prompt treatment can help decrease visual impairment. This study evaluated the role of teleophthalmology in underserved rural areas along with cost-saving estimates for the end user.

Methods:
A prospective, observational, cross-sectional hospital-based study was conducted over 3 months. First 1000 teleconsultations were included. None of the patients denied providing informed consent. The patients were consulted at the eight vision centers and three satellite centers of the hospital in the nearby rural and tribal regions closer to their residential places. These vision and satellite centers were connected to the base hospital like a hub and spoke model with a teleophthalmology network.

Results:
Cataract (n = 301, 30.1%) and refractive error (n = 290, 29%) were the most common diagnosis. 42.1% of patients were referred to base hospital for further evaluation. Thus, a total of 57.9% of patients were not required to visit the base hospital for initial consultation, saving time and money. Furthermore, 15.1% of patients were provided medical treatment at the vision center and satellite center, which helped in making teleophthalmology cost-saving for the patients. An average of Rs. 621/- were saved per patient for the community in our study.

Conclusion:
Networked teleophthalmology model can be an affordable and feasible tool for providing eye care delivery services in rural and tribal regions of Gujarat and the whole country, especially for the end user. Thus, it may be a workable model in ophthalmology practice with substantial cost saving to the community.
Diabetic microaneurysms detected by fluorescein angiography spatially correlate with regions of macular ischemia delineated by optical coherence tomography angiography
Authors: Abdel-Kader Ahmed A , Ramsey David J , Yussuf Wael A , Mohalhal Ahmed A , Eldaly Mohamed A , Elnahry Ayman G 
Published: August 2023

Purpose:
To characterize the relationship between diabetic macular ischemia (DMI) delineated by optical coherence tomography angiography (OCTA) and microaneurysms (MAs) identified by fundus fluorescein angiography (FFA).

Methods:
Patients with diabetic retinopathy (DR) who underwent OCTA and FFA were retrospectively identified. FFA images were cropped and aligned with their respective OCTA images using i2k Align Retina software (Dual-Align, Clifton Park, NY, USA). Foveal avascular zone (FAZ) and ischemic areas were manually delineated on OCTA images, and MAs were marked on the corresponding FFA images before overlaying paired scans for analysis (ImageJ; National Institutes of Health, Bethesda, MD, USA).

Results:
Twenty-eight eyes of 20 patients were included. The average number of MAs identified in cropped FFA images was 127 ± 42. More DMI was noted in the superficial capillary plexus (SCP; 36 ± 13%) compared to the deep capillary plexus (DCP; 28 ± 14%, P < 0.001). Similarly, more MAs were associated with ischemic areas in SCP compared to DCP (92.0 ± 35.0 vs. 76.8 ± 36.5, P < 0.001). Most MAs bordered ischemic areas; fewer than 10% localized inside these regions. As DMI area increased, so did associated MAs (SCP: r = 0.695, P < 0.001; DCP: r = 0.726, P < 0.001). Density of MAs surrounding FAZ (7.7 ± 6.0 MAs/mm2) was similar to other DMI areas (SCP: 7.0 ± 4.0 MAs/mm2, P = 0.478; DCP: 9.2 ± 10.9 MAs/mm2, P = 0.394).

Conclusion:
MAs identified in FFA strongly associate with, and border areas of, DMI delineated by OCTA. Although more MAs are localized to SCP ischemia, the concentration of MAs associated with DCP ischemia is greater. By contrast, few MAs are present inside low-flow regions, likely because capillary loss is associated with their regression.
A pilot non-randomized trial of smartphone-based anaglyph system for treatment of adult amblyopia through VR (Virtual Reality)
Authors: Sutar Samir , Maan Veenu , Chaurasiya Ritesh Kumar , Agarwal Pradeep , Omaer Mossab , Chauhan Lokesh , Sengar Ajay Kumar , Kumari Bhavana 
Published: August 2023

Purpose:
To evaluate the effectiveness of amblyopia treatment through a smartphone-based anaglyph system by virtual reality (VR) in adult patients.

Methods:
A total of 10 subjects diagnosed with anisometropic amblyopia were enrolled during the study period. Best Corrected Visual Acuity (BCVA), stereoacuity, and contrast acuity were evaluated during three visits (at presentation, 3 months and 6 months) of smartphone-based anaglyph video run in the VR mode. All the amblyogenic factors including stereopsis, color vision, and contrast acuity were compared using Friedman two-way analysis of variance. Statistical significance was considered if P < 0.05.

Results:
Mean BCVA in amblyopic eye improved significantly from a logMAR value of 0.73 ± 0.64 before Virtual reality vision therapy (VRVT) to a post-training VRVT value of 0.48 ± 0.44 (P < 0.01). Mean stereoacuity changed from a value of 560.00 ± 301.58 before VRVT to a value of 263.00 ± 143.58 seconds of arc after training (VRVT) (P < 0.01). Mean accommodation changes from a value of 15.00 ± 7.40 before training or VRVT to value of 12.60 ± 6.10 cm after training (P < 0.01). Mean contrast acuity changes from a value of 1.21 ± 0.72 at presentation to a value of 1.52 ± 0.49 log unit after VRVT.

Conclusion:
A smartphone-based anaglyph system using VR vision therapy appears to be an effective treatment option for amblyopia in adults.
Topographic distribution of retinal neovascularization in proliferative diabetic retinopathy using ultra-wide field angiography
Authors: Nidhi Vatsala , Verma Saurabh , Shaikh Nawazish , Azad Shorya V , Chawla Rohan , Venkatesh Pradeep , Vohra Rajpal , Kumar Vinod 
Published: August 2023

Purpose:
To analyze the topographic distribution of neovascularization (NV) and capillary nonperfusion (CNP) using ultra-wide field fluorescein angiography (UWFFA) in patients with proliferative diabetic retinopathy (PDR).

Methods:
This was a prospective, single-center, observational study in which all patients who presented between March 2019 and December 2020 and satisfied the inclusion criteria were recruited. In our study, patients with treatment-naïve PDR without any fibrovascular proliferation underwent UWFFA. The images were analyzed qualitatively for the topographic distribution of NV and the CNP area was quantified. The number of lesions picked by UWFFA was compared with 7 standard field (7SF) image using overlay of 7SF. The main outcome measure was characteristics of neovascularization, such as the number, location, and area of CNP, measured using UWFFA, which was considered with 95% confidence intervals (CI).

Results:
Two hundred and fifty-three eyes of 187 patients with a mean age of 56.03 ± 8 years were included. Mean neovascularization elsewhere (NVE) was 2.91 ± 3.43. Maximum NVEs were seen in the superotemporal (ST; 0.9 ± 1.13) quadrant, followed by the inferotemporal (IT; 0.7 ± 1.08), inferonasal (IN; 0.66 ± 1.02) and superonasal (SN; 0.66 ± 1.01) quadrants. Maximum CNP area was seen in the SN (13.75 ± 8.83 disc diameter square [DD2]) quadrant, followed by the IN (13.48 ± 8.59 DD2), IT (11.34 ± 8.37 DD2), and ST (11.3 ± 8.34 DD2) quadrants. Mean CNP area was maximum in patients with only neovascularization of disc (NVD; 64.99 ± 41.47 DD2), followed by both NVD and NVE (61.37 ± 35.61 DD2), and was minimum in patients with only NVE (36.44 ± 22.03 DD2). Eighty-one (32%) eyes out of 253 had NVE and 189 (75%) out of 253 had CNP area outside 7SF (overlay) of Early Treatment Diabetic Retinopathy Study (ETDRS).

Conclusion:
Diabetic NV lesions and CNP areas are distributed asymmetrically throughout the retina and are not restricted to the posterior pole. Compared to conventional 7SF imaging, UWFFA reveals significantly more retinal vascular pathology in patients with PDR.
Study 3: Anterior segment optical coherence tomography-guided surgical approach in slipped medial rectus muscle
Authors: Pujari Amar , Maddu Sai Vineeth , Batwani Vineet Kumar , Khokhar Sudarshan , Jha Paritosh , Sharma Namrata 
Published: August 2023

Purpose:
To discuss the novel swept-source anterior segment optical coherence tomography (SS-ASOCT)-guided surgical approach in slipped medial rectus muscles.

Methods:
Prospectively (between February 2020 and July 2022), six patients with a clinical suspicion of slipped medial rectus muscle were recruited. After complete ophthalmic and orthoptic evaluation, the missing medial rectus muscle is screened using Anterior Segment Optical Coherence Tomography (ASOCT). In presence of a traceable muscle, its morphology, depth, and distance from a fixed anatomical landmarks were noted; in its absence, the status of other recti was noted. Intraoperatively, the features were confirmed and the intended intervention was performed.

Results:
The mean age of six patients was 25.66 ± 9.72 years, two with surgical trauma and four with penetrating trauma (66.66%). In five patients, the ASOCT traced the slipped medial rectus muscle successfully (83.33%); intraoperatively, the same was confirmed (within 1–2 millimeters) with favorable outcomes. ASOCT made a significant contribution in all subjects by reducing the number of interventions and muscle surgeries.

Conclusions:
In eyes with slipped medial rectus muscle, especially those which are within a finite distance from the angle can be traced using ASOCT. This approach impacts the outcomes in many ways.