bluuebunny/crossref_metadata_2025_split huggingface dataset:
In-vitro Corrosion-Induced Strength-Ductility Degradation in WE43 and ZX10 Magnesium Alloy Fine Wires for Biomedical Applications
Authors: Ulugun Beril , Raguraman Sreenivas , Osei-Owusu Nana Barimah , Raj Sneha , Ramirez Clarence , Griebel Adam , Weihs Timothy P. 
Published: January 2025

Abstract

With an increasing demand for biodegradable structural materials, magnesium (Mg) alloys stand out as promising candidates. Here, we investigate the corrosion-induced mechanical degradation of fine wires made from WE43 and ZX10 Mg alloys, evaluating their suitability for biomedical applications such as scaffolds, stents, and sutures. Both alloys exhibit distinct microstructural features that influence their corrosion and mechanical behavior. WE43 wires, characterized by neodymium-rich precipitates and elongated grains, showed significant axial pitting corrosion and a rapid decline in mechanical properties attributed to micro-galvanic corrosion and potential hydrogen embrittlement. In contrast, ZX10 wires, featuring coarser and heterogeneously distributed Mg2Ca precipitates, demonstrated extensive localized pitting but retained higher ductility and toughness over extended exposure. Micro-CT analyses reveal that precipitate size, distribution, and volume fraction critically influence corrosion morphology and mechanical degradation. The findings emphasize the importance of tailoring alloy microstructures to enhance corrosion resistance and mechanical performance. While WE43's higher corrosion rates and more rapid property degradation limit its potential in applications with fine dimensions, ZX10's lower corrosion rate and higher mechanical resilience make it a more viable candidate. Future research should prioritize developing chemically homogeneous precipitates in ZX10 that are small and uniformly distributed.
Effectiveness of kinesiotherapy for tension-type headache and chronic non-specific back pain: A prospective randomized study
Authors: Golovacheva A. A. , Golovacheva V. A. , Fateeva T. G. 
Published: January 2025

Introduction. Kinesiotherapy is effective in the complex treatment of patients with tension-type headache (TTH) and patients with chronic nonspecific back pain (CNBP). However, few randomized studies have been conducted on the effectiveness of kinesiotherapy in patients with TTH and CNBP.Aim. To evaluate the effectiveness of complex treatment, including kinesiotherapy, in patients with TTH and CNBP.Materials and methods. The study included 100 patients (23 men, 77 women, mean age 38.8 ± 9.3 years). Patients were randomized into two groups. Group 1 received complex treatment (specialized kinesiotherapy, standard drug and non-drug therapy), group 2 – standard therapy. All patients were assessed for clinical and psychological parameters at baseline and after 3 and 6 months of treatment.Results. After 3 months of treatment, the clinical effect (CE) in the treatment of TTH (decrease in headache (H) frequency by 50% or more) and CNBP (decrease in back pain (BP) intensity according to the numeric rating scale, the Oswestry questionnaire indicator by 30% or more) in group 1 was achieved by 88% of patients, which is statistically significantly (p < 0.05) greater than in group 2 (44% of patients). More than a third (36%) of patients in group 1 did not have H and BP after 3 months, while there were no such patients in group 2. After 6 months of observation, all achieved CEs were maintained in group 1, 38% of patients achieved complete remission of H and BP; in group 2, CE was maintained only in 33% of patients, and no patient showed complete regression of HB and BP.Conclusion. Complex treatment, including kinesiotherapy, in patients with TTH in combination with CNBP leads to a rapid (after 3 months) positive effect, which lasts for a long time (6 months).
Synthesis, Characterization and Evaluation of Antimicrobial and Antioxidant Activities of Novel Chalcone Scaffolds
Authors: Mittapalli Sathish Kumar , Parashar Deepesh , S. Roshan , M V Neethu , Mahor Ajay , Gupta Pawan Kumar , Pamu Sagar , Rizwana Iffath 
Published: January 2025

Background:
Synthetic antibiotics are often much more potent than natural alternatives.
They can effectively treat serious and life-threatening bacterial infections.

Methods:
The chalcones were synthesized by Claisen-Schmidt condensation and characterized by
FT-IR, 1HNMR, 13CNMR and MS methods. All the compounds underwent computational and invitro
evaluations for antimicrobial and antioxidant properties.

Results:
The docking studies indicated that all the molecules displayed good binding energy with
their selective targets, with 6g and 6h showing the best affinity among them. The antimicrobial test
results showed that the MIC values ranged from 0.4 to 0.9 mg/ml, and compounds 6g and 6h demonstrated
potential for gram-positive bacteria. At the same time, 6k and 6l displayed good inhibition
activity against gram-negative bacteria. Compound 6k showed potential against Candida albicans,
and compound 6l showed potential against Aspergillus Niger. However, compound 6b showed poor
antimicrobial activity. Compounds 6g and 6f also exhibited ferrous ion chelating activity at 28.69
μg/ml and 29.94 μg/ml, respectively.

Conclusion:
Based on the IC50 values, it was found that only compounds 6g and 6f had superior
against oxidation, which was evaluated using EDTA as a reference. The ADMET properties were
analyzed using SwissADME. Furthermore, the lead likeness results showed that 6g exhibited leadlike
characteristics.
Potentiometric Ion-selective Electrode for the Determination of Antazoline in Different Formulations and Biological Fluids Using Biomimetic Receptors
Authors: Hussein Ola G. , Rostom Yasmin , Mahmoud Amr M. , Abdelkawy Mohamed , Rezk Mamdouh R. , Ahmed Dina A. 
Published: January 2025

Background:
Traditional analysis techniques usually involve separation and pre-treatment
steps prior to analysis, resulting in time and solvent consumption. In contrast, a potentiometric ion
selective electrode is a simple, environmentally friendly, and cost-effective technique that is used as
an alternative analytical technique, utilizing the efficacy of potentiometric sensors used in stability
research and quality control investigations.

Methods:
An innovative Antazoline selective membrane sensor was constructed and evaluated to
detect Antazoline in its pure form, eye drop formulations, degradation products, and biological fluid.
Sensor fabrication was achieved using potassium tetrakis borate and polyvinyl chloride polymeric
matrix plasticized with 2-nitrophenyl octyl ether and using calix[8]arene (CX8) as an ionophore. A
comparative potentiometric study was implemented using two sensors, one using an ionophore and
the other lacking the ionophore.

Results:
Linear responses of Antazoline were obtained utilizing sensors 1 and 2 in concentration
ranges of 1.0×10-2 to 1.0×10-7 mole/L and 1.0×10-2 to 1.0×10-6 mole/L, correspondingly. Nernstian
slopes of 58.486 and 51.2 mV/decade over pH 8.0 were attainted using 1 and 2 sensors, respectively.

Conclusion:
The proposed method was applied to determine antazoline without any need for any
pretreatment or separation steps in both formulated eye drops Trillerg® sterile ophthalmic solution
and Otrivine- Antistin® Eye Drops as well as in rabbit aqueous humor and the presence of its degradation
products. Estimation of the method's greenness was confirmed using several assessment tools.
Safety and Efficacy of Anlotinib-based Regimen in Patients with Unresectable or Metastatic Bone and Soft-tissue Sarcomas: A Retrospective Institutional Study
Authors: Pang Lina , Zhang Shengli , Wang Liye , Gong Shuai , He Wei 
Published: January 2025

Background:
Anlotinib has demonstrated durable clinical benefits in patients with unresectable or
metastatic bone and soft-tissue sarcomas.

Methods:
92 patients treated with chemotherapy combined with or without anlotinib were collected and analyzed.
The objective response rate (ORR) and disease control rate (DCR) were analyzed. Long-term survival was assessed
using the Kaplan-Meier method, including median progression-free survival (mPFS) and overall survival
(mOS).

Results:
Liposarcoma, synovial sarcoma, and rhabdomyosarcoma were the primary pathological subtypes of the
92 patients. The median age was 46 (range, 11–75) years. The ORR and DCR of the anlotinib-chemotherapy
combination used as first-line therapy were 31.9% and 85.1%, respectively. However, the ORR and DCR were
only 6.7% and 57.8% in the chemotherapy alone, respectively. Compared with the chemotherapy group, improvements
were observed in the mPFS and mOS with anlotinib-based regimen (mPFS, 8.3 vs. 3.0 months; mOS,
59.0 vs. 22.0 months). Anlotinib-associated adverse events were well tolerated and mainly occurred in grades I
and II. New anlotinib-related adverse reactions were not noted.

Conclusion:
Anlotinib-based regimen as a first-line therapy showed a positive effect on the treatment of unresectable
or metastatic BSTSs. The anlotinib-associated adverse events were minor and well tolerated.
Awareness of Sexual Partner’s HIV Status Among Men Who Have Sex With Men in China: Cross-Sec. tional Survey Study
Authors: Ma Qian , Jiang Tingting , Chen Wanjun , Jiang Shaoqiang , Zheng Jinlei , Wang Hui , He Lin 
Published: January 2025

Abstract

Background
Men who have sex with men (MSM) constitute a significant proportion of individuals living with human immunodeficiency virus. Over the past few years, China has implemented various strategies aimed at increasing the rate of HIV testing and reducing HIV transmission among MSM. Among these, the disclosure of HIV serostatus is an effective prevention strategy.

Objective
This study aimed to assess HIV serostatus disclosure and identify factors associated with awareness of sexual partners’ HIV status among MSM to provide a scientific basis for promoting HIV testing and reducing HIV transmission.

Methods
A cross-sectional study based on a large-scale web-based survey was conducted among MSM in Zhejiang province, China, between July and December 2023. MSM who were HIV-negative or had an unknown HIV status were recruited from the Sunshine Test, a web-based platform that uses location-based services to provide HIV prevention services. Participants were required to complete a questionnaire on demographic characteristics, sexual behavior, rush popper use, awareness of sexual partners’ HIV status, and knowledge of pre-exposure prophylaxis (PrEP) and postexposure prophylaxis (PEP). A multinomial regression model was used to identify the factors associated with awareness of sexual partners’ HIV status.

Results
A total of 7629 MSM participated in the study, with 45.2% (n=3451) being aware, 35.4% (n=2701) being partially aware, and 19.4% (n=1477) being unaware of their sexual partner’s HIV status. The multinomial logistic regression analysis revealed the following results. Compared to those who were unaware of their sexual partner’s HIV status, participants who were students (adjusted odds ratio [aOR] 1.43, 95% CI 1.09‐1.86), had a monthly income of more than US $1400 (aOR 1.36, 95% CI 1.03‐1.80), had insertive anal sex (aOR 1.35, 95% CI 1.12‐1.63), had only male sexual partners (aOR 1.53, 95% CI 1.28‐1.82), had 1 sexual partner in the past 3 months (aOR 2.36, 95% CI 2.01‐2.77), had used condoms for the past 3 months (aOR 1.72, 95% CI 1.33‐2.22), had frequently used rush poppers in the past 3 months (aOR 2.27, 95% CI 1.81‐2.86), were aware of HIV PrEP (aOR 2.04, 95% CI 1.68‐2.48), were aware of HIV PEP (aOR 1.69, 95% CI 1.39‐2.06), used mail reagent self-testing (aOR 1.19, 95% CI 1.04‐1.36), and had previously undergone HIV testing (aOR 1.40, 95% CI 1.16‐1.69) were associated with increased odds of being aware of their sexual partner’s HIV status.

Conclusions
Overall, 45.2% of MSM who were HIV-negative or had an unknown status were aware of their sexual partners’ HIV status in China. We suggest strengthening targeted interventions through web-based platforms and gay apps to promote the disclosure of HIV serostatus and reduce HIV transmission among MSM.
Recent Advances in Physiotherapy Intervention on Patellofemoral Pain Syndrome - A Systemic Review
Authors: K Aishwarya , Dash Smruti Swagatika , Kachhwaha Rajendra 
Published: January 2025

Background: Patellofemoral Pain Syndrome (PFPS) is a prevalent knee condition characterized by anterior or retro patellar pain, often triggered by activities like climbing stairs, squatting, or prolonged sitting. It arises from multifactorial causes, including malalignment, muscular imbalances, and biomechanical abnormalities. Recent physiotherapy advancements aim to enhance pain management, muscle function, and knee stability, emphasizing patient-centered approaches.
Methodology: Eligible studies included randomized controlled trials (RCTs), cohort studies, and case series focusing on patients with PFPS. Data extraction encompassed patient demographics, intervention protocols, and outcome measures, including the Visual Analog Scale (VAS) and Anterior Knee Pain Scale (AKPS).
Results: The review synthesized findings from 10 RCTs with 1,472 participants. Neuromuscular training, kinesiology taping, high-intensity laser therapy, and patient education were identified as effective short-term interventions. Combined therapies demonstrated superior outcomes in pain reduction, functional improvement, and muscle strength compared to isolated approaches. However, variations in follow-up durations and small sample sizes limited insights into long-term efficacy.
Conclusion: This review highlights the need for a multifaceted, individualized treatment approach for PFPS. Neuromuscular stimulation, targeted exercise, and patient education emerged as effective strategies for pain management and functional recovery. Future research should focus on long-term outcomes and the integration of patient-specific biomechanics into treatment protocols.
Parvovirus B19-associated purpureo-petechial exanthema. Differential diagnosis with non-infectious vasculitis
Authors: Haliullina S. V. , Anohin V. A. , Lutfullin I. Ya. , Dolgovskova D. E. , Nazarova O. A. 
Published: January 2025

Clinical manifestations of parvovirus B19 infection are varied and depend on the age, hematological and immune status of the infected person. Classic manifestations of the disease include infectious erythema in children, arthritis/ arthralgia in adults, severe anemia in patients with impaired erythropoiesis and non­immune hydrops fetalis in case of intrauterine infection. In addition, various types of exanthema associated with parvovirus B19 have been described. These include “papular­purpuric gloves and socks syndrome, PPGSS”, “purpuro­petechial rash associated with parvovirus B19, PAPPE”, “acropethechial syndrome”, “asymmetric periflexural exanthema of children”, etc. In all cases, skin manifestations are characterized by a hemorrhagic rash. A certain difficulty is the differential diagnosis of such variants of parvovirus B19 infection with vasculitis of non­infectious origin, primarily with the most common IgA vasculitis (Henoch­Schonlein purpura) and cutaneous small vessel vasculitis (CSVV). The connection of vasculitis with infection in some cases is obvious and is confirmed by epidemiological observations. Infections can act as a trigger for the development of vasculitis or be its direct cause (vasculitis in this case can be classified as “vasculitis associated with a probable etiology” in the nomenclature system of the Chapel Hill Consensus Conference 2012). Considering that the nature of vasculitis is not completely clear, the question of a possible connection between their occurrence and infection with PVB19 requires further study. From a clinical point of view, the differential diagnosis of hemorrhagic exanthema associated with PVB19 and vasculitis is extremely important primarily because of the need for immediate treatment of the latter. From an epidemiological point of view, this is important, since patients with PPGSS or PAPPE are infectious throughout the period of the rash.Apparently, additional studies, primarily histological, of a sufficient number of samples from patients with purpuric­petechial rash and serologically proven acute parvovirus B19 infection will help solve this problem.
Mandatory IFRS Adoption and Design Innovation
Authors: Chiu Peng-Chia , Hsu Po-Hsuan , Tian Feng , Yi Long 
Published: January 2025

ABSTRACT
We use the mandatory adoption of International Financial Reporting Standards (IFRS) in 2005 as an exogenous change in reporting regulations, examining how it affects design innovation. We find that mandatory IFRS adoption is positively related to firms’ likelihood of winning the iF Product Design Award, which acknowledges excellent product/service designs. We also find that after IFRS adoption, firms attract more international institutional investors who can better monitor and advise on product designs. The impact of this IFRS mandate is more pronounced for firms with expanded international sales, which may benefit more from international markets. Overall, our results enhance our understanding of how mandatory IFRS adoption affects firms’ innovation activities.
Особенности репрезентации концепта жизнь в лирике Н. А. Заболоцкого в свете теории регулятивности
Authors: Исаева Ольга Викторовна 
Published: January 2025

Концепт жизнь, являясь ключевым для национальной картины мира и творчества Н. А. Заболоцкого, находит отражение в творчестве поэта как раннего периода, представленного сборником «Столбцы и поэмы», так и позднего периода («Стихотворения (1932–1958)»). Поскольку содержание и средства репрезентации концепта претерпевают изменения вместе с разным мироощущением автора, представляется актуальным выявление динамики в творчестве известного поэта. Целью статьи является изучение особенностей репрезентации концепта жизнь в лирике Н. А. Заболоцкого на основе теории регулятивности, разработанной в коммуникативной стилистике текста. Представлены результаты анализа стихотворений, написанных в разные годы. Использованы различные методы анализа, включая концептуальный, биографический, сравнительно-сопоставительный, которые позволили выявить регулятивные средства и способы репрезентации ключевого концепта жизнь и отражение в них динамики его поэтической картины мира. В ранней лирике Н. А. Заболоцкий представляет жизнь как череду карнавальных шествий, наполненных одушевленными предметами. В позднем творчестве восприятие жизни поэтом меняется. Под влиянием натурфилософского учения поэт тесно связывает жизнь природы и жизнь человека, которые наделены разумом, чувствами и гармонично дополняют друг друга.
The concept of life, being the key to the national picture of the world and the creations of N. A. Zabolotsky, is reflected in the poet’s creations both of the early period, represented by the collection «Columns and Poems», and of the late period («Poems (1932-1958)»). The content and means of representation of the concept changed with the author’s different worldview, it seems relevant to identify the dynamics in the work of the famous poet. The goal of the article is to study the peculiarities of the representation of the concept of life in N.A. Zabolotsky’s lyrics based on the theory of regularity developed in the communicative style of the text. The article contains the results of the analysis of poems written in different years. Various methods of analysis was used in the research, including conceptual, biographical, comparative, which made it possible to identify regulatory means and ways of representing the key concept of life and reflecting in them the dynamics of his poetic picture of the world. In his early lyrics, N.A. Zabolotsky presents life as a series of carnival processions filled with animate objects; life is turned upside down. In his later creations, the poet’s perception of life changes. Being influenced of natural philosophy, the poet closely connects the life of nature and human life, which are endowed with reason, feelings and harmoniously complement each other.
The Challenges of the Sharia Economy and Businesses In Facing the Coronavirus Endemic and Circular Economy In Indonesia
Authors: Jam'an  , Asdar  , Nur Sandi Marsuni  
Published: January 2025

The outbreak of the coronavirus pandemic has had significant negative effects on various sectors, including the economy in Indonesia. These adverse impacts have also extended to the Sharia-based financial and business sectors. This study aims to identify and explore the challenges faced by the Islamic economy and industry in the aftermath of the coronavirus pandemic and its on going endemic nature. A qualitative research approach was used, drawing from various studies and prior research findings. The study reveals a decline in several Sharia products and challenges in Sharia production, largely due to a heavy dependence on imported raw materials. This issue continues to affect businesses within the Sharia-based economic and financial sector, ultimately limiting investment opportunities. Consequently, with government support, actors in the Sharia economy and business sector need to reassess growth targets and leverage digital technology to recover from the economic disruptions caused by the coronavirus endemic. Research Implications Sharia-based businesses should diversify supply chains to reduce dependence on imports and adopt digital technology to boost resilience and competitiveness. The government can support recovery by providing incentives and fostering innovation in Sharia-compliant products to ensure sustainable growth.
Effect of reduced tillage practices on yield, total protein content and weed infestation of winter barley
Authors: Woźniak Andrzej 
Published: January 2025

A multi-year field experiment aimed to evaluate grain yield, yield structure elements, total protein content, and weed infestation indices of winter barley cultivated in a conventional tillage system (CT) and two no-tillage variants: (i) reduced without glyphosate (RT) and (ii) reduced with glyphosate (RT + G). Common peas served as the previous crop in each study year on all plots. Shallow ploughing and pre-sowing ploughing were applied in the CT system after previous crop harvest. In turn, cultivating instead of shallow ploughing and a cultivation unit (a cultivator + a string roller) instead of pre-sowing ploughing were used on RT plots. Finally, shallow ploughing was replaced by glyphosate treatment, whereas pre-sowing ploughing – by a cultivation unit in the RT + G system. A higher grain yield was determined on CT plots than RT and RT+G plots, i.e., by 18% and 23.3%, respectively. The grain yield was also observed to differ significantly between study years. Spike number and 1000 grain weight were differentiated by tillage practices, whereas plant number after emergence by study years. There were no differences in the protein content of winter barley grain as affected by the variants of tillage practices and study years. In contrast, the weeds produced a higher air-dry weight on RT plots than on CT and RT + G plots. Weed bio-diversity determined at the tillering stage was greater on RT than CT plots, whereas that assessed at the milk maturity stage on CT than RT + G plots. The weed diversity index was determined by study year in both terms of assessment.