bluuebunny/crossref_metadata_2025_split huggingface dataset:
Alport syndrome: an update
Authors: Savige Judy 
Published: January 2025

Purpose of review
The recent widespread availability of genetic testing has resulted in the diagnosis of many more people with Alport syndrome. This increased recognition has been paralleled by advances in understanding clinical consequences, genotype-phenotype correlations and in the development of new therapies.

Recent findings
These include the international call for a change of name to ‘Alport spectrum’ which better reflects the diverse clinical features seen with autosomal dominant and X-linked Alport syndrome; the demonstration of how common Alport syndrome is in people with haematuria, proteinuria, or kidney failure; the inability of current genetic testing to detect all pathogenic variants in suspected Alport syndrome; the different genotype-phenotype correlations for autosomal dominant and X-linked disease; and the novel treatments that are available including SGLT2 inhibitors for persistent albuminuria despite renin-angiotensin-aldosterone blockade, as well as early studies of gene-modifying agents.

Summary
Autosomal dominant Alport syndrome is the commonest genetic kidney disease and X-linked Alport syndrome is the second commonest genetic cause of kidney failure. Both these diseases are frequently seen in the renal clinic, and clinicians should be aware of their likelihood in a person with persistent glomerular haematuria, proteinuria or kidney failure. Autosomal dominant Alport syndrome is so common that it also occurs coincidentally in other kidney diseases especially IgA nephropathy.
Hourglass Constriction of a Single Fascicle of the Anterior Interosseous Nerve
Authors: Sreedharan Sadhishaan , Shukla Lipi , Edmondson Mark , Ferris Scott 
Published: January 2025

Abstract
Hourglass fascicular constrictions have been reported in fewer than 100 cases globally and only in the upper limb. The etiology remains unknown. Patients often present with self-limiting pain in the affected limb followed by flaccid paralysis. As the external architecture of the nerve remains normal on traditional radiological studies, the diagnosis can be missed. The purpose of this case report is to describe this rare clinical entity and a successful treatment approach including ultrasound localization and targeted intraneural microsurgical neurolysis followed by excellent functional recovery.
Predictors for clinically significant prostate cancer detection: Insights from transperineal software-assisted fusion biopsy and transperineal cognitive fusion biopsy
Authors: Jong Bor-En , Lo Chi-Wen , Yang Stephen Shei-Dei , Yu Chih-Chin , Hsu Chun-Kai , Li Ming-Wei , Tseng Shen-Shiou , Tsai Pin-Hsuan , Chou Yi-Ju , Chang Chia-Lun , Tsai Yao-Chou 
Published: January 2025

Purpose:
To compare the effectiveness of transperineal software-assisted fusion biopsy (TSAFB) and transperineal cognitive fusion biopsy (TCFB) in identifying predictors for detecting clinically significant prostate cancer (csPCa).

Materials and methods:
Conducted from December 2022 to December 2023 at a single center, this retrospective cohort study included male patients with prostate-specific antigen levels >4 ng/mL or positive digital rectal examination findings and suspicious lesions on multiparametric magnetic resonance imaging (MRI) (Prostate Imaging and Reporting Data System ≥3). The study compared TSAFB using the KOELIS Trinity MRI TPUS Biopsy System with TCFB. The primary outcome was the detection rate of csPCa. Secondary outcomes included the detection rate of clinically insignificant prostate cancer (cisPCa) and the overall detection rate combining csPCa and cisPCa.

Results:
The study analyzed 31 TSAFB and 17 TCFB procedures. Baseline demographic and clinical parameters showed no significant differences between the cohorts. TSAFB had higher median total and targeted core counts. Both TSAFB and TCFB demonstrated similar detection rates for prostate cancer, csPCa, and cisPCa. Adopting a targeted-only strategy with TCFB led to nearly 20% of cancers going undetected. Logistic regression identified prostate-specific antigen density >15% and lesion/prostate ratio as significant predictors for csPCa detection.

Conclusion:
TSAFB and TCFB are comparably effective in detecting csPCa. Prostate-specific antigen density >15% and lesion/prostate ratio as strong predictors for csPCa detection highlights the importance of high-quality imaging modalities such as 3T MRI for precise volume measurements of the prostate and lesions. Nevertheless, the study underscores the critical importance of incorporating systematic biopsies in TCFB to avoid missing prostate cancer cases.
Phase transitions in
H2−HD−D2
mixtures up to 350 GPa
Authors: Xu Haian , Xu Wan , Wang Pu , Liu Lin , Liu Xiao-Di , Gregoryanz Eugene 
Published: January 2025

Utilizing the high-pressure low-temperature Raman and optical transmission/absorption spectroscopies, we have mapped out the phase diagram of H2-HD-D2 alloy with the initial H:D concentration 50:50 up to 350 GPa between 10 and 300 K. We followed the phase lines between all known solid phases [I, II, III, IV, and IV′ (IV+V)] of pure H2 and D2 constraining their locations in the wide space. We trace the phase boundary separating phases III and IV(IV′)/V demonstrating that this phase line has a steep negative slope (−0.95 K/GPa), which becomes shallower at above 250 GPa (−0.55 K/GPa). The phase line follows the trend observed in the pure species. Additionally, we find that the band gap of the mixture between 300 and 360 GPa is close to those of the pure species suggesting that alloying one isotope by another would not significantly shift the metallization pressure. These observations imply that hydrogen deuteride (HD) has very similar properties to those exhibited by the pure species.

Published by the American Physical Society
2025
Maximally entangled gluons for any
x
Authors: Hatta Yoshitaka , Montgomery Jake 
Published: January 2025

Individual quarks and gluons at small x inside an unpolarized hadron can be regarded as Bell states in which qubits in the spin and orbital angular momentum spaces are maximally entangled. Using the machinery of quantum information science, we generalize this observation to all values 0<x<1 and describe gluons (but not quarks) as maximally entangled states between a qubit and a qudit. We introduce the conditional probability distribution P(lz|sz) of a gluon’s orbital angular momentum lz given its helicity sz. Restricting to the three states lz=0,±1, which constitute a qutrit, we explicitly compute P as a function of x.

Published by the American Physical Society
2025
Understanding the effect of galvanic corrosion on the sulfide stress corrosion cracking of X80/Inconel 625 weld overlay
Authors: Liu Bosheng , Zhang Yan , Wang Qinying , Liu Li , Dong Lijin 
Published: January 2025

Purpose
This study aims to investigate the effect of galvanic corrosion on the sulfide stress corrosion cracking (SSCC) of X80/Inconel 625 weld overlay by altering the cathode/anode area ratios, Na2S2O3 concentrations and temperatures.

Design/methodology/approach
The effects of galvanic corrosion on X80/Inconel 625 weld overlay SSCC were investigated by immersion test, galvanic corrosion current test, electrochemical measurement, four-point bending experiment, hydrogen permeation experiment and scanning electron microscopy.

Findings
The anodic dissolution of the fusion boundary was enhanced as the cathode/anode area ratio increased, which is necessary for the SSCC of the X80/Inconel 625 weld overlay. However, severe galvanic corrosion reduced the SSCC susceptibility. The SSCC susceptibility showed a linear increase with Na2S2O3 concentration in the range of 10−4 ∼ 10−2 mol/L. However, further increasing the Na2S2O3 concentration to 10−1 mol/L resulted in the disappearance of SSCC. This is likely because sufficient hydrogen was required for SSCC initiation even under severe anodic dissolution conditions, which was further supported by the reduced SSCC susceptivity at elevated temperatures.

Originality/value
Limited studies aim to establish the relationship between the galvanic corrosion and SSCC of welded joints through altering the cathode/anode area ratios, Na2S2O3 concentrations and temperatures. This work will pave the way for understanding the effect of galvanic corrosion on the SSCC of dissimilar weld joints.
The role of intuition and rationality in the causation-effectuation decision-making puzzle
Authors: Zimmermann Clarice , de Vasconcellos Silvio Luis , Faccin Kadigia , Tontini Gerson , Parente Ronaldo Couto 
Published: January 2025

PurposeWe aim to explore the role of the interplay between intuition and rationality in the causation-effectuation decision-making processes of small creative businesses during their international expansion.Design/methodology/approachWe developed process research to investigate the causation-effectuation decision-making processes during the internationalization of a creativity-intensive small business located in Brazil. In just three years, its cartoon reached screens in 80 countries.FindingsWe discovered an orthogonal relationship between causation and effectuation moderated by the balance between intuition and rationality, enabling small creative businesses to successfully navigate internationalization by adapting to contractual demands and exploring creative opportunities. To explain these relationships, we offer five process-based propositions for further studies.Research limitations/implicationsWe reconstructed the internationalization process based on retrospective interviews, so eliminating all biases from rationalization may have been impossible. We elucidate the interrelationship between causation-effectuation decision-making logic and demystify that decision-making effectuation logic is predominantly intuitive. We provide evidence that rational thinking permeates the entire decision-making process as a process of building the future.Practical implicationsUnderstanding causation-effectuation decision-making processes in creativity-intensive small businesses can be helpful for other businesses because they nurture production on a large scale.Social implicationsThe study emphasizes the importance of creativity-intensive small businesses to countries’ economies. Creativity-intensive businesses grow in other industries and generate many jobs in mature industries.Originality/valueWe demystify the decision-making assumption that effectuation logic is predominantly intuitive while causation logic is rational. Instead, we show that these logics coexist and interact orthogonally and dynamically.
Understanding novice school leaders’ turnover intentions: the role of leadership dynamics
Authors: Richard Tobias 
Published: January 2025

PurposeThis study investigated how leader characteristics, interpersonal dynamics, and situational context may predict turnover intentions among novice principals and assistant principals.Design/methodology/approachA quantitative survey was administered to 1,945 novice school leaders in Sweden. Linear regression analysis was conducted to identify factors contributing to turnover intentions and to compare the predictive influences between principals and assistant principals.FindingsThe results indicate that leader characteristics such as gender, emotional stability and self-efficacy, interpersonal dynamics like trust and emotional containment and situational context factors including role demands and managerial support, significantly shape turnover intentions. The overall pattern of factors influencing turnover intentions was similar for both principals and assistant principals, with some differences observed.Practical implicationsThe study underscores the limitations of one-dimensional strategies, advocating for a comprehensive approach to enhancing school leader retention. Effective interventions should address individual attributes, foster trust within teams and strengthen organizational support structures.Originality/valueThis research provides fresh insights into the turnover intentions of novice school leaders, emphasizing that a combination of factors across different domains predicts turnover intentions. The findings support the development of multi-faceted, context-sensitive strategies for retaining school leaders.
Examining integrated care training and practice implementation within academic medical settings: perceptions, attitudes and barriers
Authors: Lister Holly , Toto Anna Marie , Marcello Stephanie , O’Kane Thomas , Hilton Katie 
Published: January 2025

PurposeIntegrated care (IC) improves patient outcomes, patient and provider experiences and healthcare costs. Still, education and interprofessional experiential training in IC is limited. There is a lack of studies examining current practices, perceptions and barriers to implementing IC training. Specifically, no studies to date assess training and practice across multiple health professions and roles (student/faculty/clinicians) within an academic medical institution or university, a gap this study sought to address.Design/methodology/approachThis cross-sectional study examined current clinical and training practices, attitudes about IC and barriers to IC practice, learning and training through a survey distributed to faculty, clinicians and students (n = 220) in nine departments of health professions within a large academic health system.FindingsThe majority of respondents reported that activities promoting IC occur often, including consultation with other professions in patient care settings, incorporation of IC concepts into teachings and interprofessional learning opportunities. Respondents endorsed willingness to practice IC, high perceived benefits of IC on patient outcomes and cultural benefits of IC. The most strongly endorsed barriers were related to resources and organizational culture. Knowledge barriers were not strongly endorsed.Originality/valueIn the most comprehensive study of attitudes toward IC to date, clinicians, students and faculty alike endorsed favorable attitudes about IC, supporting the acceptability of incorporating IC education and training into curricula. IC is seen as enhancing experiences, competence and professional marketability of providers-in-training, indicating it is a desired focus of future practice for many healthcare providers.
How do digital knowledge resources affect the carbon emission intensity of the pig industry?
Authors: Xie Yanhua , Yang Yimin , Yang Lulu 
Published: January 2025

Purpose
By exploring the impact of digital knowledge resources (DKR) on the carbon emission intensity of the pig industry (PCEI), this study aims to reveal the role of DKR in reducing PCEI.

Design/methodology/approach
Based on provincial panel data in China from 2011 to 2021, this study uses the entropy and Intergovernmental Panel on Climate Change coefficient methods to calculate the evaluation index system of DKR and PCEI, respectively. Empirical analysis using a panel fixed-effects model examines the influence of DKR on PCEI and its underlying mechanisms.

Findings
DKR can significantly reduce PCEI. This conclusion still holds even after undergoing endogeneity treatment and a series of robustness tests. Mechanism test results indicate that DKR can operate indirectly through the mediation mechanism of rural human capital (RHC) and pig breeding technology innovation (PTI), while environmental regulation intensity (ERI) plays a positive moderating role in the relationship between DKR and PCEI. The magnitude of the impact of DKR on PCEI depends on ERI. Further studies found that the impact of DKR on PCEI has obvious heterogeneity characteristics, and the promotion effect is more obvious in regions with good integration degrees and high development potential.

Practical implications
This paper divides DKR into three dimensions: digital technology knowledge (DTK), digital management knowledge (DMK) and digital application knowledge (DAK), providing a new framework for research and enriching the understanding of the relationship between DKR and PCEI. Furthermore, the research results reveal the application potential of DKR in the pig industry, particularly in terms of resource allocation efficiency. This is of great significance for promoting low-carbon development in the pig industry and provides insights for the low-carbon transformation of other industries. In addition, the study emphasizes the moderating effect of ERI on the mechanism of carbon reduction in the pig industry through DKR. This offers a new perspective for understanding the relationship between knowledge management and environmental governance, providing a reference basis for policy formulation in related fields.

Originality/value
This paper further enriches the role of DKR in the livestock industry. Integrating DKR with traditional industries promotes knowledge innovation, information distribution and utilization and scientific decision-making. This has significant value in promoting the development and application of carbon reduction technologies, enhancing industrial competitive advantages, and other aspects.
Fashion countdown to Halloween: a study of dress practices within American Halloween consumer culture
Authors: Smith-Glaviana Dina Cherise , Shields Delaney 
Published: January 2025

Purpose
This study aims to explore the dress practices of American (US) consumers who wear Halloween fashion products to extend theories related to dress and appearance.

Design/methodology/approach
A qualitative, exploratory study using an online survey with open-ended and close-ended questions. Data were analyzed using qualitative content analysis.

Findings
Sixty-two survey responses were analyzed using qualitative content analysis. The results provided insight into social norms for wearing holiday fashion products and that consumer perceptions of the ideal timing for wearing Halloween fashion products may vary based on individuals’ enthusiasm for Halloween. Rather than the social and physical setting, timing restricted or increased the level at which wearers could express their enthusiasm for Halloween. Earlier in the year, respondents felt their freedom of expression was restricted, driving them to wear subtle Halloween fashion products. As Halloween day approached, respondents experienced more freedom in expressing their enthusiasm for the holiday by wearing clothing and accessories more explicitly related to Halloween.

Research limitations/implications
This study extends theory relating to dress and appearance as it acknowledges timing as an element of social context in which identities are established through appearance.

Practical implications
Retailers may consider selling Halloween fashion items that are small and/or less Halloween-specific, “spooky”, gothic earlier in the year.

Originality/value
This study is original in that it explores the timing in which consumers use holiday fashion products. Except for investigating consumer perceptions regarding the timing of retail promotions, researchers have seldom investigated timing as a consideration in constructing an individuals’ identity and appearance.
Optimizing urban block layouts and density distribution: a generative design framework for neighborhood performance
Authors: Mavahebi Tabatabai Ghazal , Tahsildoost Mohammad , Ardekani Amirreza , Zomorodian Zahra Sadat 
Published: January 2025

PurposeIn many countries, urban block layouts follow rigid and outdated design guidelines; however, these approaches fail to effectively address settlement construction, neighborhood planning, the design of old urban contexts and the rapid development of emerging cities, as seen in the new towns of Iran and various other regions worldwide. Revising these guidelines requires early-stage decision-making to evaluate building layouts based on their impact on the built environment. This study introduces a workflow for optimizing urban block layouts with constant density while considering design constraints, climate and environmental performance. This framework assists planners and policymakers in refining site density distribution and building massing.Design/methodology/approachA computational urban design method was developed utilizing a grasshopper-based algorithm and Python for data generation. It introduces an innovative approach by incorporating buildings’ placement coordinates as design variables alongside dimensions and orientation. The Wallacei tool optimizes layouts by considering energy use intensity (EUI), outdoor thermal comfort and facades’ received radiation employing Ladybug Tools. Spatial daylight autonomy (sDA) and urban heat island (UHI) effects are also integrated into the workflow. The framework is applied to a hypothetical residential district in Tehran, consisting of nine blocks, each containing nine plots.FindingsThe results for a set of optimal solutions demonstrate that beyond existing urban design policies, environmentally prioritized designs are achievable. Radiation differences between the optimal models and the conventional parallel layout range from 41.3 to 61.1%. However, changes in EUI and universal thermal climate index (UTCI) are minimal; significant improvements are observed in sDA, with 7, 8 or all 9 buildings meeting the acceptable threshold compared to none in the parallel layout. These findings highlight the effectiveness of the design method framework proposed in this research, which has the potential to significantly influence urban planning practices across various regions globally.Originality/valueThe methodology of this study provides a flexible decision-making framework for early design phases, enabling policymakers, architects and urban designers to address the gap between current urban design methods and environmentally driven approaches. Sensitivity analysis of optimal solutions further offers valuable insights into the correlation between design variables and evaluation metrics.
Forging a relationship between quality management and sustainable development in higher education institutions: insights from a cross-country Kano study
Authors: Grunwald Guido , Kara Ali , Spillan John E. 
Published: January 2025

PurposeThis study’s objective is to offer a process to adapt the Kano model as a quality management (QM) tool for prioritizing students’ sustainability transformation requirements of higher education institutions (HEIs).Design/methodology/approachData for this study were gathered from business students enrolled in bachelor’s programs at two state universities in the USA and one public university in Germany. In total, 239 students participated in the survey. For the Kano analysis, instead of selectively applying various evaluation rules and quality criteria, an integrative-sequential analysis process involving three steps is employed to enhance classification quality.FindingsResults show that sustainability transformation expectations and their priority orders differ across the countries studied. Although the Kano model as a QM tool has not been extensively used by HEIs to gauge students’ sustainability expectations, it offers significant potential as part of a comprehensive process to translate stakeholder sustainability needs into HEIs’ actions.Originality/valueAs the first study adapting the Kano model as a QM tool for use in HEIs’ sustainability transformations, our study contributes to the growing body of research on incorporating QM tools and customer and stakeholder orientation into the sustainability context at HEIs.