bluuebunny/crossref_metadata_2025_split huggingface dataset:
Probing a $$\textrm{Z}^{\prime }$$ with non-universal fermion couplings through top quark fusion, decays to bottom quarks, and machine learning techniques
Authors: Barbosa Diego , Díaz Felipe , Quintero Liliana , Flórez Andrés , Sanchez Manuel , Gurrola Alfredo , Sheridan Elijah , Romeo Francesco 
Published: May 2023

AbstractThe production of heavy neutral mass resonances, $$\text {Z}^{\prime }$$

Z
′

, has been widely studied theoretically and experimentally. Although the nature, mass, couplings, and associated quantum numbers of this hypothetical particle are yet to be determined, current LHC experimental results have set strong constraints assuming the simplest beyond Standard Model (SM) hypotheses. We present a new feasibility study on the production of a $$\text {Z}^{\prime }$$

Z
′

boson at the LHC, with family non-universal couplings, considering proton–proton collisions at $$\sqrt{s} = 13$$

s

=
13

and 14 TeV. Such a hypothesis is well motivated theoretically and it can explain observed differences between SM predictions and experimental results, as well as being a useful tool to further probe recent results in searches for new physics considering non-universal fermion couplings. We work under two simplified phenomenological frameworks where the $$\textrm{Z}^{\prime }$$

Z
′

masses and couplings to the SM particles are free parameters, and consider final states of the $$\text {Z}^{\prime }$$

Z
′

decaying to a pair of $$\textrm{b}$$
b
quarks. The analysis is performed using machine learning techniques to maximize the sensitivity. Despite being a well motivated physics case in its own merit, such scenarios have not been fully considered in ongoing searches at the LHC. We note the proposed search methodology can be a key mode for discovery over a large mass range, including low masses, traditionally considered difficult due to experimental constrains. In addition, the proposed search is complementary to existing strategies.
Efficient Rendering for Light Field Displays using Tailored Projective Mappings
Authors: Fink Laura , Strobel Svenja , Franke Linus , Stamminger Marc 
Published: May 2023

A standard paradigm when rendering for parallax-based light field displays is to render multiple, slightly offset views first and to interweave these afterwards. In practice, more than 40 views of preferably high resolution need to be rendered per frame to achieve acceptable visual quality. The total amount of rendered pixels may consequently exceed the native resolution of the display by far. Increased memory consumption and sub-optimal render times are direct consequences.
In this paper, we examine where pixels are "wasted" and present novel projective mappings for the virtual camera system that are custom tailored to such displays. Thus, we alleviate the aforementioned issues and show significant performance improvements regarding render time and memory consumption, while having only minor impact on visual quality. As we mainly touch the projective mapping of the virtual camera, our method is lean and can easily be integrated in existing rendering pipelines with minimal side effects.
Evolutions of Anisotropic Hydraulic Properties of Rough-Walled Rock Fractures under Different Shear Displacements
Authors: Lu Dapeng 
Published: May 2023

Four cylindrical sandstone samples were extracted from the original rectangular sample with a rough-walled fracture. Each drilling angle (θ) of cylindrical sandstone samples is different to consider the anisotropies of rough-walled rock fractures. For each sample, different flow velocities ranging from 0 m/s to 13 m/s were designed. For a given flow velocity, a series of different confining pressures (

σ

n

), including 1.5 MPa, 2.5 MPa, and 3.5 MPa, were applied on the fractured samples. The hydraulic properties of each cylindrical sandstone sample were tested under different shear displacements (

u

s

) and

σ

n

. The results show that the hydraulic gradient (

J

) shows an increasing trend with the increment of

σ

n

. With the increment of the Reynolds number (

Re

), the transmissivity (

T

) decreases in the form of the quadratic function. The normalized transmissivity (

T
/

T

0

) decreases with the increment of

J

. The variations in

T
/

T

0

with

J

can be divided into three stages. The first stage is that

T
/

T

0

approximately holds a constant value of 1.0 when

J

is small indicating that the fluid flow is in the linear regime. The last two stages are that

T
/

T

0

decreases with the continuous increase of

J

, and the reduction rate first increases and then decreases. The critical Reynolds’ number (

Re

c

) of the sample angle with a drilling angle of 90° is different from that of other samples. The corresponding

Re

c

is 6.52, 28.73, and 32.1 when the shear displacement

u

s

=
2

mm

, 3 mm, and 4 mm, respectively. The variations in

Re

c

and

J

along different drilling angles are significantly obvious. When the confining pressure is large, the effect of anisotropy on Rec is much greater than that of confining pressure.
Targeting CHAF1B Enhances IFN Activity against Myeloproliferative Neoplasm Cells
Authors: Saleiro Diana , Kosciuczuk Ewa M. , Fischietti Mariafausta , Perez Ricardo E. , Yang G. Sohae , Eckerdt Frank , Beauchamp Elspeth M. , Hou Ye , Wang Qixuan , Weinberg Rona Singer , Fish Eleanor N. , Yue Feng , Hoffman Ronald , Platanias Leonidas C. 
Published: May 2023

Interferons (IFNs) are cytokines with potent antineoplastic and antiviral properties. IFNα has significant clinical activity in the treatment of myeloproliferative neoplasms (MPN), but the precise mechanisms by which it acts are not well understood. Here, we demonstrate that chromatin assembly factor 1 subunit B (CHAF1B), an Unc-51-like kinase 1 (ULK1)-interactive protein in the nuclear compartment of malignant cells, is overexpressed in patients with MPN. Remarkably, targeted silencing of CHAF1B enhances transcription of IFNα-stimulated genes and promotes IFNα-dependent antineoplastic responses in primary MPN progenitor cells. Taken together, our findings indicate that CHAF1B is a promising newly identified therapeutic target in MPN and that CHAF1B inhibition in combination with IFNα therapy might offer a novel strategy for treating patients with MPN.

Significance:
Our findings raise the potential for clinical development of drugs targeting CHAF1B to enhance IFN antitumor responses in the treatment of patients with MPN and should have important clinical translational implications for the treatment of MPN and possibly in other malignancies.
Pulmonary Artery Pressure-Guided Heart Failure Management Reduces Hospitalizations in Patients With Chronic Kidney Disease
Authors: Raval Nirav Y. , Valika Ali , Adamson Philip B. , Williams Christopher , Brett Marie-Elena , Costanzo Maria Rosa 
Published: May 2023

Background:
Hemodynamic-guided heart failure management is a superior strategy to prevent decompensation leading to hospitalization compared with traditional clinical methods. It remains unstudied if hemodynamic-guided care is effective across severities of comorbid renal insufficiency or if this strategy impacts renal function over time.

Methods:
In the CardioMEMS US PAS (Post-Approval Study), heart failure hospitalizations were compared from 1 year before and after pulmonary artery sensor implantation in 1200 patients with New York Heart Association class III symptoms and a previous hospitalization. Hospitalization rates were evaluated in all patients grouped into baseline estimated glomerular filtration rate (eGFR) quartiles. Chronic kidney disease progression was evaluated in patients with renal function follow-up data (n=911).

Results:

Patients with stage 2 or greater chronic kidney disease at baseline exceeded 80%. Heart failure hospitalization risk was lower in all eGFR quartiles ranging from a hazard ratio of 0.35 (0.27–0.46;
P
<0.0001) in patients with eGFR >65 mL/min per 1.73 m
2
to 0.53 (0.45–0.62;
P
<0.0001) in patients with eGFR ≤37 mL/min per 1.73 m
2
. Renal function was preserved or improved in most patients. Survival was different between quartiles and lower in quartiles with more advanced chronic kidney disease.

Conclusions:
Hemodynamic-guided heart failure management using remotely obtained pulmonary artery pressures is associated with lower hospitalization rates and general preservation of renal function in all eGFR quartiles or chronic kidney disease stages.
Reach Out Emergency Department: A Randomized Factorial Trial to Determine the Optimal Mobile Health Components to Reduce Blood Pressure
Authors: Skolarus Lesli E. , Dinh Mackenzie , Kidwell Kelley M. , Lin Chun Chieh , Buis Lorraine R. , Brown Devin L. , Oteng Rockefeller , Giacalone Michael , Warden Kimberly , Trimble Deborah E. , Whitfield Candace , Farhan Zahera , Flood Adam , Borgialli Dominic , Montas Sacha , Jaggi Michael , Meurer William J. 
Published: May 2023

Background:
Mobile health (mHealth) strategies initiated in safety-net Emergency Departments may be one approach to address the US hypertension epidemic, but the optimal mHealth components or dose are unknown.

Methods:
Reach Out is an mHealth, health theory-based, 2×2×2 factorial trial among hypertensive patients evaluated in a safety-net Emergency Department in Flint, Michigan. Reach Out consisted of 3 mHealth components, each with 2 doses: (1) healthy behavior text messaging (yes versus no), (2) prompted self-measured blood pressure (BP) monitoring and feedback (weekly versus daily), and (3) facilitated primary care provider appointment scheduling and transportation (yes versus no). The primary outcome was a change in systolic BP from baseline to 12 months. In a complete case analysis, we fit a linear regression model and accounted for age, sex, race, and prior BP medications to explore the association between systolic BP and each mHealth component.

Results:

Among 488 randomized participants, 211 (43%) completed follow-up. Mean age was 45.5 years, 61% were women, 54% were Black people, 22% did not have a primary care doctor, 21% lacked transportation, and 51% were not taking antihypertensive medications. Overall, systolic BP declined after 6 months (−9.2 mm Hg [95% CI, −12.2 to −6.3]) and 12 months (−6.6 mm Hg, −9.3 to −3.8), without a difference across the 8 treatment arms. The higher dose of mHealth components were not associated with a greater change in systolic BP; healthy behavior text messages (point estimate, mmHG=−0.5 [95% CI, −6.0 to 5];
P
=0.86), daily self-measured BP monitoring (point estimate, mmHG=1.9 [95% CI, −3.7 to 7.5];
P
=0.50), and facilitated primary care provider scheduling and transportation (point estimate, mmHG=0 [95% CI, −5.5 to 5.6];
P
=0.99).

Conclusions:
Among participants with elevated BP recruited from an urban safety-net Emergency Department, BP declined over the 12-month intervention period. There was no difference in change in systolic BP among the 3 mHealth components. Reach Out demonstrated the feasibility of reaching medically underserved people with high BP cared for at a safety-net Emergency Departments, yet the efficacy of the Reach Out mHealth intervention components requires further study.

Registration:

URL:
https://www.clinicaltrials.gov
; Unique identifier: NCT03422718.
License to Cull: A Research Agenda for Investigating the Necropolitics of Countryside Culling and Urban Pest Control
Authors: von Essen Erica , Redmalm David 
Published: May 2023

Abstract
This paper proposes an empirical research agenda for investigating the practices of biosecuritization of wild animal threats in modern society. Previously mostly studied on the lofty biopolitical level of directives on combatting invasive species or culling pests, we outline the conceptual and methodological points of entry for bringing the on-the-ground work of culling out-of-place, unwanted, individual animals and populations. This means a focus on necropolitics as constituted by the norms, everyday professional practices, vernaculars of killing, and identity work by pest controllers in the city and hunters on the countryside. Borrowing from research in the domestic animal killing context, we nevertheless show how wild animal killing is imbued with more spontaneity, remorse, aesthetics, public stigma, and multispecies entanglements, requiring adapted research protocols.
Writings and the Authority of the Church Fathers in Old Polish Apocryphal Texts
Authors: Rojszczak-Robińska Dorota 
Published: May 2023

Abstract
The article presents relations between Old Polish biblical-apocryphal narrations to Church Fathers’ texts. There are numerous questions: which Church Fathers were known to Old Polish authors? What were specific writers’ preferences? Were the choices made by Polish authors different in this respect from the European practice? How were Fathers’ writings translated? Was there any difference in how patristic texts were used compared to other works (canon and non-canon works)? Were Old Polish authors aware that Fathers’ writings were present in texts by other Christian authors? Nonetheless, the two questions I put at the very centre of my research is: 1) what are the writings and the authority of the Church Fathers used for, and what is the purpose of referring to the Fathers; 2) what is the image of the Church Fathers and patristics that is present in the Old Polish authors’ texts.
New biographical data on Adriaen van de Venne (1590-1662) and his family
Authors: Buijsen Edwin , Nijboer Harm 
Published: May 2023

In his biography of Adriaen Pietersz van de Venne in Het gulden cabinet van de edel vry schilderconst (1661-1662) Cornelis de Bie devotes a few lines to the painter’s early years. Until recently, this was all the information we had regarding the origins, childhood and training of this versatile artist. Fresh biographical data for Adriaen van de Venne and his family, however, has recently become available from the digitized archival records of Delft, Leiden, Rotterdam and Zeeland indexed in the online Ecartico database, an initiative of the University of Amsterdam. Combining these archival discoveries enhances our understanding of the milieu in which Adriaen grew up and of his family network.
He is highly likely to have been born in 1590 (rather than 1589 as hitherto assumed) and baptized in the church in ’t Woudt, near Delft. His parents were migrants from the Southern Netherlands: the stocking maker Pieter van de Venne from Lier and Jannetgen Beuvincx from Tournai. Adriaen’s father died before his birth and his mother remarried in Delft in 1594 to the Mechelen weaver Laurens Wittocx. This second marriage produced a son called Salomon Lourens, who became a ‘coarse painter’ and bricklayer in Rotterdam. Adriaen remained in contact with this half-brother for his whole life.
Adriaen relied heavily at first on his older brother Jan, who probably arranged an apprenticeship for him with Simon de Valck, a goldsmith friend in Leiden. He later followed his brother to Middelburg, where they set up a successful printing, publishing and art dealing firm. Shortly before Jan’s death in 1625, Adriaen moved to The Hague, from where he kept in contact with his half-brother Salomon Lourens in Rotterdam. They acted as joint guardians of their nephew Pieter (one of Jan’s sons), who also lived in Rotterdam and worked there as a parchment maker. Archive documents from Rotterdam testify to the close links that persisted between the branches of the family in Rotterdam and The Hague. Adriaen possibly used his Rotterdam family connections to sell his paintings in this city.
Cornelis Tromp’s trophies: The origins of a late portrait (1675-1676) by Ferdinand Bol
Authors: Van Eikema Hommes Margriet , Van Der Werf Inez , Bakker Piet , Kirsch Kathrin 
Published: May 2023

In 2018, Het Scheepvaartmuseum in Amsterdam acquired a portrait of Lieutenant-Admiral Cornelis Tromp (1629-1691), painted by Ferdinand Bol, from a private collection. Previously, this work was only known from a reproduction print by Lambert Visscher. After its acquisition, the portrait was restored in 2019, which is when its material and (art) historical aspects were examined.
In the portrait, Tromp wears two insignia: a diamond portrait medallion on a red ribbon and the badge of the Danish Order of the Elephant. This badge was added to the portrait later, but by Bol himself. Tromp was thus initially depicted wearing only one of the insignia: the diamond medallion with the red ribbon. That Bol regarded this version of the portrait as completed is evidenced by the egg-white varnish he applied to it. At a later stage however, he exchanged this insignia for the badge of the Order of the Elephant. He carefully hid the medallion and ribbon from view by first scraping off their paint and then obscuring the remains of these forms with a layer of grey paint. Finally, he added the insignia of the Order of the Elephant. During a later restoration, the paint Bol used to cover the medallion and ribbon was largely removed, revealing these forms once again.
The ship in the background is the Gouden Leeuw (Golden Lion), Tromp’s flagship during the Third Anglo-Dutch War (1672-1674). Since Tromp had received the portrait medallion from the English king in January 1675, the first portrait version can be dated to February 1675 at the earliest and May 1676 at the latest, when Tromp was appointed commander-in-chief of the Danish fleet in Denmark. After Tromp was elevated to the Order of the Elephant upon his arrival in Copenhagen, Bol altered the portrait to keep it in step with Tromp’s career. This chronology sheds new light on Bol’s artistic practice. which was always assumed to have ended in 1669 when Bol married the wealthy widow Anna van Erckel. However, Tromp’s portrait demonstrates that Bol continued to paint into the second half of the 1670s.
After his elevation to the Order of the Elephant, Tromp only allowed himself to be portrayed with this insignia, which was always depicted correctly. It was only Bol who depicted the badge incorrectly, indicating that he did not make the adjustment at Tromp’s instigation. Presumably Bol did this of his own initiative, or that of his wife’s, Anna van Erckel. Archival evidence strongly suggests that she was the first owner of the portrait and that she also owned a portrait, painted by Bol, of Tromp’s wife Margaretha van Raephorst. It was not previously known that Bol had painted her, however a portrait by him of an anonymous woman is clearly Van Raephorst’s likeness. Archival documents show that Van Erckel and Bol knew the Tromp couple personally and maintained friendly relations with them. In Bol and Van Erckel’s stately canal house, the portraits would have been ‘proof’ of that personal relationship.
Stratosphere–Troposphere Coupling during Sudden Stratospheric Warmings with Different North Atlantic Jet Response
Authors: Martínez-Andradas Verónica , de la Cámara Alvaro , Zurita-Gotor Pablo 
Published: May 2023

Abstract
Sudden stratospheric warmings (SSWs) are extreme disruptions of the wintertime polar vortex that can alter the tropospheric weather for over 2 months. However, the reasons why only some SSWs have a tropospheric impact are not yet clear. This study analyses the tropospheric impact of SSWs over the Atlantic region as measured by the latitudinal displacement of the North Atlantic eddy-driven jet following SSWs. We use reanalysis data for the period 1950–2020 to examine differences in the stratospheric and tropospheric circulation for SSWs with an equatorward (EQ) or a poleward (POLE) shift. Our results show a stronger and more persistent Northern Annular Mode (NAM) signal in the lower stratosphere for EQ than for POLE, beginning 2 weeks before the onset date. In the troposphere, we find precursory signals of the Atlantic jet behavior over Siberia, consistent with previous studies, and also over the central North Pacific and central Europe. In particular, our results suggest that the noncanonical poleward jet shift response to SSWs is in part modulated by circulation anomalies over the central North Pacific, and that these are in turn connected to the cold phase of El Niño–Southern Oscillation. Further analysis of the enhanced predictability given by these precursors suggests that the sign of the lower-stratospheric NAM and the geopotential anomalies over the central North Pacific significantly affect the probability of having an EQ or POLE response of the Atlantic jet.
An atypical presentation of sympathetic ophthalmia following chemical ocular burns
Authors: Bansal Pooja , Singh Maninder , Gupta Yashi , Gotmare Nikhil , Thakar Meenakshi , Arora Ritu 
Published: May 2023

Abstract
Background
Sympathetic ophthalmia is a rare disease that can present as bilateral granulomatous uveitis after a penetrating trauma or surgery in one eye.

Findings
We report a case of a 47-year-old male with history of decreased vision in the right eye, six months after sustaining severe chemical injury in the left eye. He was diagnosed with sympathetic ophthalmia and was treated with corticosteroids and long-term immunosuppressive therapy, leading to complete resolution of intraocular inflammation. Final visual acuity was 20/30 at one year of follow up.

Conclusions
Sympathetic Ophthalmia following chemical ocular burns is extremely uncommon. It can present as a diagnostic and therapeutic challenge. It warrants early diagnosis and management.
Population structure analysis to explore genetic diversity and geographical distribution characteristics of wild tea plant in Guizhou Plateau
Authors: He Limin , Luo Jing , Niu Suzhen , Bai Dingchen , Chen Yanjun 
Published: May 2023

AbstractBackgroundTea, the second largest consumer beverage in the world after water, is widely cultivated in tropical and subtropical areas. However, the effect of environmental factors on the distribution of wild tea plants is unclear.ResultsA total of 159 wild tea plants were collected from different altitudes and geological types of the Guizhou Plateau. Using the genotyping-by-sequencing method, 98,241 high-quality single nucleotide polymorphisms were identified. Genetic diversity, population structure analysis, principal component analysis, phylogenetic analysis, and linkage disequilibrium were performed. The genetic diversity of the wild tea plant population from the Silicate Rock Classes ofCamellia gymnogynawas higher than that from the Carbonate Rock Classes ofCamellia tachangensis. In addition, the genetic diversity of wild tea plants from the second altitude gradient was significantly higher than that of wild tea plants from the third and first altitude gradients. Two inferred pure groups (GP01 and GP02) and one inferred admixture group (GP03) were identified by population structure analysis and were verified by principal component and phylogenetic analyses. The highest differentiation coefficients were determined for GP01 vs. GP02, while the lowest differentiation coefficients were determined for GP01 vs. GP03.ConclusionsThis study revealed the genetic diversity and geographical distribution characteristics of wild tea plants in the Guizhou Plateau. There are significant differences in genetic diversity and evolutionary direction betweenCamellia tachangensiswith Carbonate Rock Classes at the first altitude gradient andCamellia gymnogynawith Silicate Rock Classes at the third altitude gradient. Geological environment, soil mineral element content, soil pH, and altitude markedly contributed to the genetic differentiation betweenCamellia tachangensisandCamellia gymnogyna.