bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lifestyle of medical students
Authors: Žnidarič Matej , Zavodnik Iza , Lučič Šrajer Lucijan 
Published: February 2023

Purpose: Using the World Health Organization definition that a healthy lifestyle is a way of living that lowers the risk of serious illness or early death, our goal was to examine the lifestyle changes made by medical students over the years of study. A healthy lifestyle, which is crucial to maintain and protect health, is determined by many variables, both positive and negative.
Methods: A total of first, third and fifth year medical students at the Faculty of Medicine of the University of Maribor (165 students, 57 males and 108 females) were enrolled in the study during the academic year 2017/18. Lifestyle data, including physical activity, nutrition, sleep hygiene, and drug, tobacco and alcohol use, were collected using a standardized self-assessment questionnaire, the FANTASTIC Lifestyle Assessment Instrument, which had been translated into Slovenian. The questionnaire was supplemented with further questions to explore psychological aspects of lifestyle, such as mental well-being, social inclusion, altruism and student activities.
Results: Our sample of first, third and fifth year medical students revealed unhealthy changes in life habits, which were closely associated with the length of training. For the third year students, the situation had reached a crisis point, probably because the initial enthusiasm over choice of study had worn off, and stress had become less managable in the transition period between preclinical and clinical training. During their third year, the students consumed the largest amount of controlled substances and prescription and OTC drugs (p=0.003), lacked goals and purpose in life, were less connected with the faculty (p=0.000) and showed a decline in altruism (p=0.007).
Conclusions: Our results show that the psychophysical stress burden among medical students increases with duration of training, reaching crisis point during the third year. We recommend that medical students should arrange self-help and support groups to maintain a healthier lifestyle during this challenging period.
Strain indicators in the assessment of systolic myocardial function in aboy with hypertrophic cardiomyopathy: a case report
Authors: Chernykh Nadezhda , Tarasova Alla , Groznova Olga 
Published: February 2023

Purpose: This article is about an unusual clinical case of a 14-year-old boy with hypertrophic cardiomyopathy (HCM).Ejection fraction (EF) and shortening fraction (FS) of the left ventricle in children with HCM remain within a normal range for an extended period of time. Therefore, detection of a decrease in segmental myocardial contractility at the initial stage of the disease presents a diagnostic problem.
Methods: The clinical characteristics of the patient, study results, and analysis of the left ventricular myocardial strain using 2D speckle-tracking mode in an echocardiographic examination are presented.
Results: A decrease in strain indicators in the anterioseptal, anterior, and anterolateral segments of the left ventricular myocardium and a compensatory increase in the contralateral segments were revealed. This served as an indication to start treatment.
Conclusions: A decrease in strain indicators in the 2D speckle- tracking mode is most informatively represented by changes in segmental systolic function of the left ventricle at the initial stage of HCM.
Henoch–Schönlein purpura – obravnava in zdravljenje pediatričnih bolnikov severovzhodnega dela Slovenije
Authors: Močnik Mirjam , Marčun Varda Nataša 
Published: February 2023

Purpose: Henoch–Schönlein purpura (HSP) is the most common type of vasculitis in childhood and has a good prognosis. The aim of our study was to compare the clinical characteristics of children with HSP diagnosed in north–east Slovenia with existing data from other countries.
Methods: We retrospectively reviewed the data of patients with HSP in our department between 2005 and 2018, and assessed their clinical characteristics, laboratory results, and treatment at presentation. We also analysed how many patients relapsed, the causes of this, and the treatment administered. These parameters were compared with previously published research.
Results: During the study period, 123 patients with HSP were treated in our department. The median patient age was 6.0 years (interquartile range: 4–9 years) with a uniform distribution between the sexes. Along with purpura, 52.8% presented with arthropathy, 19.5% with abdominal pain, and up to 10% with renal involvement. Patients received supportive therapy the most frequently. Non–steroidal anti–inflammatory drugs were prescribed to 61.8% of patients and corticosteroids to 13%. Relapse occurred in 15.4% of patients, most presenting with skin purpura and kidney manifestations.
Conclusion: The basic demographic data of our patients were comparable to those of other similar published studies. The order of frequency of individual organ system involvement was also similar, but the percentages were lower. Purpura–accompanying manifestations were reported less often in our study than in previous studies. Compared to other studies, supportive therapy alone was prescribed more frequently to our patients, and corticosteroids were rarely administered. Compared to other studies, a smaller proportion of patients with relapse was recorded.
Report of a rare case: supernumerary tooth between the roots of the permanent maxillary first molar
Authors: Strmšek Lucija , Štamfelj Iztok 
Published: February 2023

Purpose: To present the case of a patient with an inter-radicular supernumerary tooth.
Case report: A 45–year–old male patient presented with sepsis of odontogenic origin. Oral clinical investigation and panoramic radiography revealed the presence of four avital teeth with inadequate root canal fillings, including both maxillary first molars. The right one had periapical radiolucencies, indicating periapical periodontitis. The left one had an unusual radiopaque structure between the roots. Condensing osteitis, odontoma, and benign cementoblastomawere included in differential diagnosis; however, cone-beam computed tomography (CBCT) showed a miniature supernumerary tooth located between the buccal roots of this tooth. Surgical removal of the inter-radicular tooth was not indicated, because there were no associated pathological changes. Subsequently, the right first molar was extracted as the most likely source of systemic infection. The remaining three avital teeth were endodonticallyre-treated.
Conclusion: An inter–radicular supernumerary tooth is a rare occurrence; however, it is important to take into account when evaluating a radiopacity associated with a permanent maxillary molar. Its image on conventional radiographs may be unclear due to overlap with the neighbouring roots. CBCT plays a leading role in radiologic diagnosis and the establishment of anatomical relationships.
The first successful endoscopic atraumatic coronary artery bypass graft for coronary artery disease in Slovenia
Authors: Djordjević Anže , Robič Boris , Jurič Peter , Petrovič Rene , Železnik Jernej , Antonič Miha 
Published: February 2023

Purpose: oronary artery bypass graft (CABG) using median sternotomy remains the standard care for patients with multi-vessel coronary artery disease (CAD). However, median sternotomy considerably affects morbidity and mortality after cardiac surgery. For this reason, less invasive access routes, including mini–thoracotomy or mini–sternotomy, have been developed to avoid full median sternotomy.
Case report: A 42–year–old male patient with a single–vessel CAD was admitted to the Department of Cardiac Surgery, University Medical Centre Maribor for surgical treatment. Endoscopic mammary artery harvesting and direct left internal mammary artery to left anterior descending artery anastomosis via left mini–thoracotomy were performed. The early postoperative course was uneventful and the patient was discharged on the fifth postoperative day.
Conclusion: This report presents the first case of a minimally invasive CABG procedure using endoscopic mammary artery harvesting in Slovenia.
15 let od podelitve prvih 'Dekanovih nagrad' za znanstvenoraziskovalno delo študentov na Medicinski fakulteti Univerze v Mariboru
Authors: Pahor Dušica 
Published: February 2023

Leta 2007 je vodstvo Medicinske fakultete Univerze v Mariboru (MF UM) na predlog prodekanje za raziskovalno delo sklenilo, da je treba spodbujati znanstvenoraziskovalno delo študentov, in uvedlo 'Dekanove nagrade' za najboljše študente na področju raziskovalnega dela na MF UM. S tem smo želeli, da študentje pridobijo izkušnje na področju raziskovanja, hkrati pa možnosti za vrednotenje raziskovalnega dela v času študija. Tako so študentje pridobili možnost, da kandidirajo s svojo raziskovalno nalogo za Perlachovo nagrado UM, ki se podeljuje za najboljše raziskovalne naloge študentom na UM vsako leto na različnih področjih študija.
Prve 'Dekanove nagrade' so bile podeljene pred 15 leti, in sicer 1. decembra 2008 na dan MF UM. Od takrat se nagrade podeljujejo vsako leto. Od leta 2010 se poleg teh nagrad podeljujejo še 'Dekanova priznanja' za vsa raziskovalna dela, ki so pokazala visoko kakovost, a se za nagrade niso uvrstila v najožji izbor. Nagrade in priznanja slovesno podeli vsako leto dekan in prodekan za raziskovalno dejavnost MF UM ob dnevu fakultete. Ob podelitvi nagrad se predstavi življenjepis nagrajenca in raziskovalno delo.
Management of pediatric burn injuries in a tertiary center in North-East Slovenia
Authors: Dukić Vuković Tanja , Gregorič Minja 
Published: February 2023

Purpose: Burns are serious injuries that cause permanent functional, aesthetic, and psychosocial consequences. This study aimed to examine the incidence of pediatric burns requiring hospitalization, and different treatment modalities and outcomes.
Methods: In this retrospective observational study, 28 children with burns (19 boys and nine girls) were admitted between 2014 and 2018 for treatment. We monitored the incidence of burns and analyzed different treatment modalities and treatment outcomes. Children in this study were treated at the Pediatric Intensive Care Unit and the Department of Plastic and Reconstructive Surgery of the University Medical Centre Maribor.
Results: Scalds were found to be the most common type of burns in children (68%). Children younger than 5 years of age were the most affected (75%). The average burned total body surface area was 9%. Furthermore, 89% of children needed surgical treatment. The hospitalization lasted for an average of 14.6 days, with complete healing occurring in 72% of children within 4 weeks.
Conclusions: This study showed that the most vulnerable age group of children with severe burns who required hospitalization was between 1 and 2 years and that the most common type of burn was scalding. We suggested educating parents about burns and burn injuries and how such serious incidence could be prevented, especially among the youngest children.
Cross–testing Symbolic and Connectionist Machine Learning Approaches in Specialized Acute Appendicitis Databases
Authors: Zorman Milan , Pohorec Sandi , Butolen Bojan , Žlahtič Bojan , Kokol Peter 
Published: February 2023

Purpose: In the world of learning with medical supervised machine approaches, we often face a lack of dataset objects suitable for training a classifier. Two of the most common reasons are the lack of funds to perform all of the required tests and dataset gathering, or simply the condition is too rare to collect a suitable number of cases. In this paper we present the results of a very rare opportunity to test and train classifiers on three acute appendicitis datasets with almost identical structures, but from different sources and of different sizes.
Methods: We performed a parallel variant of cross–testing of two types of classifiers (decision trees [DT] and artificial neural networks [ANN]). Our variant of cross–testing focuses on training the classifiers on one dataset and testing all of the remaining available datasets, including the one derived from the same source, as the training set. To compare the three acute abdominal pain databases of different sizes and origins, we selected 18 parameters from patient medical histories, clinical examinations, and the decision attribute/diagnosis, acute appendicitis.
Results: The comparison of results was based on overall accuracy, sensitivity, specificity, and balance.
Conclusion: The results we obtained were quite surprising, and factors such as dataset size and theoretical power of the methods did not prove to be as important as first expected.
Hormesis – an example of astrocyte response after ethanol exposure
Authors: Lipnik–Štangelj Metoda , Šarc Lucija 
Published: February 2023

Purpose: In the present work we describe hormesis and review documented hormetic responses in astroglial cells after exposure to different stressors. We present an example of the astrocyte response to acute and chronic ethanol exposure with hormetic characteristics.
Methods: As an experimental model, newborn rat cortical astrocytes in culture were used. The cells were exposed to ethanol or the primary metabolite of ethanol (acetaldehyde) for 24 h or 7 days. After treatment, the protein content was determined, and the IL–6 levels in the culture medium were measured using an enzyme– linked immunoassay.
Results: Treatment of astroglial cells with ethanol or acetaldehyde led to enhanced protein content and stimulated IL–6 production in the low concentration zone followed by diminished protein content and an inhibition of IL–6 production at higher concentrations. Chronic exposure of astrocytes was more toxic than acute exposure for both compounds, and acetaldehyde was more toxic compared to ethanol.
Conclusion: Ethanol and acetaldehyde represent stressors for cultured astrocytes and evoke a typical hormetic response after acute and chronic exposure.
Nagovor dekana red. prof. dr. Ivana Krajnca ob otvoritvi Medicinske fakultete Univerze v Mariboru 18. september 2013 / The speech of The dean and full-time professor Ivan Krajnc MD at the opening of the Faculty of Medicine of the University of Maribor on
Authors: Krajnc Ivan 
Published: February 2023

Spoštovane gospe, spoštovani gospodje!

V uvodu mi dovolite, da se vam zahvalim, da ste se udeležili naše proslave v tako velikem številu, da ste se udeležili otvoritve nove stavbe Medicinske fakultete Univerze v Mariboru.

Mineva 7 let, ko smo v vodstvu Medicinske fakultete Univerze v Mariboru (MF UM) pričeli razmišljati tudi o svojem domu.

MF je delovala na številnih lokacijah, v prostorih rektorata UM, v prostorih Univerzitetnega kliničnega centra Maribor (UKC MB) in v prostorih Zavod za zdravstveno varstvo Maribor.
La estructura informativa del doblado de predicados
Authors: Muñoz Pérez Carlos , Verdecchia Matías 
Published: February 2023

En este trabajo presentamos un análisis de la estructura informativa de la construcción del doblado de predicados en español rioplatense (por ejemplo, Leer, leyó). Nuestra propuesta es que en este tipo de estructuras el predicado dislocado funciona como un tópico contrastivo en el sentido de Büring (2003, 2016), esto es, es un elemento que evoca un conjunto de preguntas alternativas con las que contrasta. Argumentamos que esta caracterización permite dar cuenta del “efecto de continuidad” que se atestigua en esta construcción, a saber, el hecho de que las oraciones con doblado de predicados sugieren siempre una continuación que involucra otro predicado. Además, mostramos que nuestro análisis predice correctamente la distribución del doblado en contextos de subordinación.
Pengaruh Kepemimpinan, Struktur Organisasi, Lingkungan Kerja Terhadap Motivasi Kerja, dan Kinerja Karyawan Di PT Tanjung Power Indonesia
Authors: Rahmanto Arif , Hadi Rizali , Firdaus Riza 
Published: February 2023

In the current era of globalization, there is economic growth that shares a brilliant perspective, for any party or company that can compete with other companies in the same industry, whether it's a product or service business. In addition, the company certainly wants to get optimal results or in other terms wants to benefit from these business activities.In accordance with the circumstances, the company must be able to have the option to adapt to changes. With the changes - changes will directly or indirectly affect the performance of workers and will also affect the state of the company. The influence of a leader's leadership, organizational structure, and work environment is very influential on the performance or work performance of workers is very valuable for a company both internal conditions and external conditions because it will affect the goals of the company's organization. Human resources in an organization must be maintained competently so that equivalence is developed between the wishes of workers and job claims. It is not uncommon for many workers who are actually highly capable of energy, but cannot perform at work, this situation is possible due to work environment factors. It's a shame, a company that has highly skilled workers but can't work usefully.The test result proves that leadership Effect on job performance with the influence of 47,56%, Job Satisfaction has a significant effect on Job Performance with the influence of 42,3% including very enough category, Organization Structure has significant influence of 49,47%, Work environment on job performance of 46,59%, Work Motivation on job Performance of 50.49% Keywords: Leadership, Organizational Structure, Work Environment
MORINGA OLEIFERA LEAF POWDER FOR TYPE 2 DIABETES: A PILOT CLINICAL TRIAL
Authors: Sissoko Lassana , Diarra Nouhoum , Nientao Ibrahim , Stuart Beth , Togola Adiaratou , Diallo Drissa , Willcox Merlin Luke 
Published: February 2023

Background: Moringa oleifera Lam. (Moringaceae) leaves are commonly used for diabetes in Mali. This pilot clinical study aimed to evaluate its effect on post-prandial blood glucose in preparation for a larger trial.
Methods: Diabetic patients and non-diabetic healthy volunteers (35 each) were asked to fast for 13 hours on three occasions. Blood glucose was measured before and after eating 100g of white bread (at 30, 60, 90, 120, 150 and 180 minutes). On their second and third study visits, they were given 1g and 2g respectively, of M. oleifera leaf powder, 30 minutes after eating the bread. The mean paired reduction in blood glucose at each time interval and the incremental area under the curve were calculated.
Results: Ingestion of Moringa powder had no effect on blood glucose in non-diabetic participants, but in diabetic patients, it lowered blood glucose at 90 minutes. There was a trend towards lower incremental area under the curve when diabetic patients took 2g of Moringa. No side-effects were reported by any participant.
Conclusions: Moringa oleifera leaf powder reduced post-prandial glycaemia in diabetic patients. A larger study is needed to define the optimal dose and to assess whether this translates into longer-term benefits.
Epidemiology of hand, foot, and mouth disease and genetic characteristics of Coxsackievirus A10 in Taiyuan City, Shanxi Province from 2016–2020
Authors: Wang Jitao , Liu Hongyan , Cao Zijun , Xu Jihong , Guo Jiane , Zhao Lifeng , Wang Rui , Xu Yang , Gao Ruihong , Gao Li , Zuo Zhihong , Xiao Jinbo , Lu Huanhuan , Zhang Yong 
Published: February 2023

Abstract

In recent years, the prevalence of hand, foot, and mouth disease (HFMD)caused by enteroviruses other than enterovirus A71 (EV-A71) and coxsackievirus A16 (CVA16) has gradually increased. The throat swab specimens of 2701 HFMD cases were tested, theVP1regions of CVA10 RNA were amplified using RT-PCR, and phylogenetic analysis of CVA10 was performed. Children aged 1–5 years accounted for the majority (81.65%) and boys was more than girls. The positivity rates of EV-A71, CVA16, and other EVs were 15.22% (219/1439), 28.77% (414/1439), and 56.01% (806/1439), respectively. CVA10 is one of the important viruses of other EVs. A total of 52 CVA10 strains were used for phylogenetic analysis based on theVP1region, 31 were from this study, and 21 were downloaded from GenBank. All CVA10 sequences could be assigned to seven genotypes (A, B, C, D, E, F, and G), and genotype C was further divided into C1 and C2 subtypes, only one belonged to subtype C1 and the remaining 30 belonged toC2 in this study. This study emphasized the importance of strengthening the surveillance of the HFMD in order to understand the mechanisms of pathogen variation and evolution, so as to provide a scientific basis for HFMD prevention, control, and vaccine development.
Enhanced Excitation Energy Transfer under Strong Light-Matter Coupling: Insights from Multi-Scale Molecular Dynamics Simulations
Authors: Sokolovskii Ilia , Tichauer Ruth , Feist Johannes , Groenhof Gerrit 
Published: February 2023

Abstract
Transfer of excitation energy is a key step in light harvesting and hence of technological relevance for solar energy conversion. In bare organic materials energy transfer proceeds via incoherent hops, which restrict propagation lengths to nanometers. In contrast, energy transport over several micrometers has been observed in the strong coupling regime where excitations hybridise with confined light modes to form polaritons. Because polaritons have group velocity, their propagation should be ballistic and long-ranged. However, experiments indicate that organic polaritons propagate in a diffusive manner and more slowly than their group velocity. Here, we resolve this controversy by means of molecular dynamics simulations of Rhodamine molecules in a Fabry-Pérot cavity. Our results suggest that polariton propagation is limited by the cavity lifetime and appears diffusive due to reversible population transfers between bright polaritonic states that propagate ballistically at their group velocity, and dark states that are stationary. Furthermore, because long-lived dark states transiently trap the excitation, propagation is observed on timescales beyond the intrinsic polariton lifetime. These atomistic insights not only help to better understand and interpret experimental observations, but also pave the way towards rational design of molecule-cavity systems for achieving long-range coherent energy transport.
Transcriptome profiling of Antrodia cinnamomea fruiting bodies grown on Cinnamomum kanehirae and C. camphora wood substrates
Authors: Wang Yi , Zhang Yi , Yuan Xiaolong , Wang Juan , Yang Yuming , Zheng Yuan 
Published: February 2023

Abstract
Antrodia cinnamomea is a rare medicinal fungus endemic to Taiwan, China. It has a high medicinal value, being rich in bioactive components such as triterpenes and polysaccharides. However, only a few studies have been conducted on A. cinnamomea fruiting bodies grown on Cinnamomum camphora wood culture. In this study, we performed transcriptome sequencing of A. cinnamomea fruiting bodies grown on C. kanehirae (NZF) and C. camphora (XZF) wood substrates. 18391 unigenes were annotated from the obtained reads, including 592 differentially expressed genes (170 up-regulated and 422 down-regulated) mainly enriched in the carbohydrate metabolism, lipid metabolism, and amino acid metabolism pathways. Comparing the transcriptome of NZF and XZF, genes encoding acetyl CoA synthetase and acetyl CoA C-acetyltransferase, involved in the terpenoid backbone biosynthesis, were highly expressed in NZF, while genes encoding glycosyltransferases and cytochrome P450s were highly expressed in XZF. There were no significant differences in the expression of the genes encoding farnesyl diphosphate farnesyltransferase, isopentenyldiphosphate isomerase, 2,3-oxidosqualene cyclase, and terpenoid synthase between NZF and XZF. The transcriptome analysis further supports that C. camphora is feasible as an alternative host of A. cinnamomea.