bluuebunny/crossref_metadata_2025_split huggingface dataset:
Вплив комбінованих занять з фітнесу на фізичну підготовленість та формування постави у дітей молодшого шкільного віку
Authors: Протас Михайло , Іващенко Ольга , Кравчук Тетяна 
Published: September 2023

Мета дослідження – виявити ефективність впливу комбінованих занять з фітнесу для дітей молодшого шкільного віку, побудованих з урахуванням рівня їхньої фізичної підготовленості та особливостей формування постави.
Матеріали і методи. У дослідженні взяли участь 56 дітей, яким на початок експерименту виконалося 8-9 років, серед них 32 дівчини та 24 хлопця. Було сформовано чотири групи: дві експериментальних ЕГ1 (13) та ЕГ2 (16) та дві контрольні КГ1 (11) та КГ2 (16). Досліджувані експериментальних груп відвідували заняття фітнесом, а діти, що увійшли до контрольних груп займалися фізичними вправами лише під час уроків фізичної культури. У дослідженні були використані наступні методи: вивчення й аналіз літератури; аналіз відеозаписів фітнес програм; педагогічне тестування; візуальний скринінг біогеометричного профілю постави; педагогічний експеримент; методи математичної статистики.
Результати. Вимірювання рівня розвитку фізичних здібностей наприкінці експерименту показало їх значне покращення в групах, де діти додатково до основних занять фізичною культурою в школі відвідували спеціально організовані комбіновані заняття з фітнесу. Найбільш позитивними результатами дослідження стали зміни рівня стану біогеометричного профілю постави досліджуваних ЕГ1. Так, якщо на початку експерименту в ЕГ1 було 2 дитини з низьким та 11 дітей з середнім рівнем, то наприкінці вже 6 дітей мали середній, а 7 покращили свій рівень постави до високого.
Висновки. Експериментально доведено, що для дітей з вадами постави та низьким рівнем фізичної підготовленості фітнес заняття мають наповнюватися переважно низькоударними силовими вправами, які мають коригуючий вплив. До змісту комбінованих занять для дітей з нормальними показниками постави варто включати високоударні аеробні вправи та будувати заняття за класичною схемою: розминка, аеробна вершина, заминка, силовий блок та стрейтчинг.
The efficacy of GnRH agonist trigger followed by hCG add-back in normal responders for fresh embryo transfer: a case-control analysis from Vietnam
Authors: Le M.T. , Le N.S.V. , Tran N.Q.T. , Nguyen Q.H.V. , Cao T.N. 
Published: September 2023

Aim: to assess the effects of a dual trigger by gonadotrophin-releasing hormone (GnRH) agonist and low-dose human chorionic gonadotropin (hCG) on in vitro fertilization (IVF) outcomes in women with normal ovarian response.Materials and Methods. This case-control analysis comprised 118 patients who responded normally to ovarian stimulation with a GnRH antagonist protocol at Hue Center for Reproductive Endocrinology and Infertility, Vietnam, between January 2018 and October 2019. Recruitment was achieved through case-control matching: a case (with Dual trigger – group A) was paired with control (with hCG trigger – group B) in a 1:1 ratio. The primary markers of success were the retrieval of oocytes and embryological data, the pregnancy rate, and the incidence of ovarian hyperstimulation syndrome (OHSS).Results. 59 patients in group A and 59 women in group B were recruited. Two groups had comparable patient characteristics and ovarian reserve. The initial dose, total dose, duration of gonadotropin administration, and peak of estradiol level were not statistically different across groups. The number of recovered oocytes (10.3 ± 4.2 vs. 10.0 ± 3.3; p = 0.663), mature oocytes (8.6 ± 3.7 vs.8.1 ± 2.8; p = 0.346), and high-quality embryos (56.2 ± 28.9 vs. 59.8 ± 35.9; p = 0.555) was equivalent. Fertilization, clinical pregnancy, and live birth rates were comparable between the dual trigger and hCG groups. In neither group were any occurrences of OHSS seen.Conclusion. Dual trigger may substitute hCG for final oocyte maturation and fresh embryo transfer in patients with normal responses to GnRH antagonist protocol-induced ovarian stimulation without compromising IVF outcomes.
Homocysteine, cancer and oncothrombosis
Authors: Bitsadze V. O. , Slukhanchuk E. V. , Solopova A. G. , Khizroeva J. Kh. , Shcherbakov D. V. , Yakubova F. E. , Gris J.-C. , Elalamy I. , Degtyareva N. D. , Lazarchuk A. V. , Gileva M. A. , Samburova N. V. , Aslanova Z. D. , Blinov D. V. , Shkoda A. S. , Makatsariya A. D. 
Published: September 2023

Introduction. Hyperhomocysteinemia (HHC) is one of the arms in the pathogenesis of thrombotic complications in female cancer patients.Aim: to assess an HHC-related impact to developing thrombotic complications in patients with malignant neoplasms of the female genital organs and breast cancer.Materials and Methods. There were retrospectively evaluated the data collected from 236 patients: with ovarian tumors (n = 63), cervical cancer (n = 51), breast tumors (n = 64), malignant neoplasms of the uterine body (n = 58). The control group consisted of 50 women without malignant neoplasms. The analysis of homocysteine (HC) concentration, the frequency of polymorphisms of the genes encoding folate cycle enzymes MTHFR C677T, MTHFR A1298C, MTRR A66G, MTR A2756G as well as the rate of thrombotic complications was carried out. A risk of blood HC level-related thrombotic complications was assessed.Results. Plasma HC concentration comprised ≥ 22 μmol/l in 30.5 % of patients. Thrombotic complications within one year after discharge from the hospital were developed in 15.3 % cases. The risk of thrombotic complications turned out to be higher in patients with elevated plasma HC level (≥ 22 μmol/l) (odds ratio = 2.99; 95 % confidence interval = 1.11–8.08). No significantly increased prevalence of polymorphisms in the genes encoding folate cycle enzymes among female cancer patients was detected.Conclusion. Monitoring HC level in female cancer patients contributes separately to predict a likelihood of thrombotic complications. Prescribing drugs that reduce HC level (folic acid) and monitoring its concentration in female cancer patients during therapy, including chemotherapy, can potentially lower an incidence of thrombotic complications.
Magnetic resonance imaging in cervical cancer: current opportunities of radiomics analysis and prospects for its further developmen
Authors: Solopova A. E. , Nosova J. V. , Bendzhenova B. B. 
Published: September 2023

Introduction.Due to the dynamic development of modern imaging technologies in recent years, much attention has been paid to radiomics particularly texture analysis. The complexity of clinically evaluated tumor procession in cervical cancer (CC) accounts for a need to expand knowledge on applying medical imaging technologies in oncologic diagnostics spanning from predominantly qualitative analysis to a multiparametric approach, including a quantitative assessment of study parameters.Aim:to analyze the literature data on the use of radiomics and image texture analysis in diagnostics and prediction of aggressiveness of oncogynecological diseases including СС.Materials and Methods.A 2016–2023 systematic literature search was carried out in the PubМed/MEDLINE, eLibrary, Scopus databases, NCCN, ESUR, ACR resources. All publications on radiomics and image texture analysis used in CC diagnostics and prediction were investigated, with queries for key words and phrases in Russian and English: «cervical cancer», «radiomics»,«texture analysis», «oncology». The study included full-text sources and literature reviews on the study subject. Duplicate publications were excluded.Results.The features and advantages of using radiomics and image texture analysis in CC diagnostics were summarized. The introduction of the radiomic approach has expanded the views on interpretation of medical imaging data. The radiomics-based parameters extracted from digital images revealed high informativeness in some studies that contribute to improving diagnostic accuracy as well as expanding opportunities for predicting therapeutic effectiveness in CC patients.Conclusion.Radiomics used in diagnostics of oncogynecologic diseases including СС is one of the promising actively developing areas of analysis in radiology that requires to be further investigated.
Modification of Ground-Motion Models to Estimate Orientation-Dependent Horizontal Response Spectra in Strike-Slip Earthquakes
Authors: Poulos Alan , Miranda Eduardo 
Published: September 2023

ABSTRACT
A model to estimate the 5% damped response spectra of horizontal components at specific orientations is presented. The model, which explicitly accounts for directionality, is based on prior research by the authors that identified that the orientation of maximum horizontal spectral response at a site in strike-slip earthquakes tends to occur at or close to the transverse orientation with respect to the epicenter. Using a database of 1962 ground motions recorded in shallow crustal earthquakes with strike-slip faulting, it is shown that there is a significantly larger probability of exceeding orientation-independent RotD50 intensities in the transverse orientation than in the radial orientation. Furthermore, the results indicate that, on average, spectral responses in the transverse orientation are significantly larger than those in the radial orientation and that these differences become more significant as the period of the oscillator increases. For example, spectral responses in the transverse orientation are, on average, 12% larger than those in the radial orientation for 1 s oscillators and 78% larger for 10 s oscillators. A period- and orientation-dependent model is developed and calibrated to estimate 5% damped response spectral ordinates at specific orientations by modifying orientation-independent RotD50 intensities. The proposed orientation-dependent model can explicitly account for directionality by modifying the means and standard deviations of any ground-motion model that estimates RotD50 response spectral ordinates for strike-slip earthquakes to obtain probability distributions of response spectral ordinates but now at specific horizontal orientations.
Do medical and paramedical students have a better awareness regarding oral health practices and orthodontic treatment? A KAP study
Authors: Yelchuru Sri Harsha , Gowd Rudragoni Saikiran , Mudunuri Navya , S.D Vasudevan , Kovelakar Ekavenika , Tankala Ravali 
Published: September 2023

oral health is the most important for the wellbeing of the patient. But it is being neglected in the developing and the underdeveloped countries and malocclusion being the third most commonly occurring dental anomaly. Medical and paramedical students have been found to be the point of contact the community on a large scale. Hence, the present study was carried out to evaluate the awareness regarding oral health and orthodontic treratment in KIMS College. A validated self-administered questionnaire, pertaining to demographic data, awareness of oral health knowledge regarding orthodontics as a specialty were included. A total of 42 questions included in the study. The answers from the students were recorded as Yes or No on a 2-point Likert scale.Significantly higher proportions (70.7%) of the dental students were aware of the oral health practices, Orthodontic treatment and the purpose of orthodontic treatment followed by the, medical students. Female students opined with a greater frequency (70.8%) that irregular teeth have a negative impact on self-esteem and quality of life compared to male students. The Dental students have more knowledge than the health care workers on awareness of oral health practices regarding the use of mouthwashes, flossing technique etc. and also regarding the orthodontic treatment and its importance.
VELscope: The challenge for the detection of orally potentially malignant lesions
Authors: Al-Essa Hussein Sh. , Hafth Hanadi A , Fadil Adil G 
Published: September 2023

Early detection of oral cancer is crucial in improving survival rate; Identification and detection of oral potentially malignant disorders (OPMD) allow delivery of interventions to reduce the evolution of these disorders to malignancy. A variety of new and emerging diagnostic aids and adjunctive techniques are currently available to potentially assist in the detection of OPMD such as the autofluorescence technique.Pathologists utilize the autofluorescence approach to investigate body mucosa and screen for changes in tissue, which could lead to the earlier detection of pre-malignant, cancer, or other disease processes. Early identification is the most effective way to ensure treatment effectiveness, boost survival rates, and maintain a high quality of life. Autofluorescence examination of oral tissues using the VELscope has suggested as an adjunctive tool for cancer detection and diagnosis. The aim of our study was to evaluate the efficacy of the VELscope system autofluorescence to image the tissue of potentially malignant oral lesions. Also, to assess the diagnostic accuracy, sensitivity and specificity of this method.
Análise de circuitos elétricos não-lineares: o caso do conversor CA/CC de 6 pulsos
Authors: Trindade Júnior Walmeran José 
Published: September 2023

Neste trabalho é mostrada uma nova metodologia para a análise de circuitos elétricos não-lineares, com aplicação na obtenção da resposta do conversor CA/CC de pulsos. Essa nova metodologia, baseada no método de Newton, é geral no domínio do tempo e pode determinar a resposta desses circuitos tanto em regime transitório como em regime permanente.
Ru-bentonite catalyzed green Knoevenagel condensation of substituted benzaldehydes with ethyl cyanoacetate
Authors: Borah Debasis , Brahma Deepmoni , Basak Dipanwita , Saikia Hemaprobha 
Published: September 2023

The full-text of the article will be published in the English version of the journal "Catalysis in Industry" No. 1, 2024.To develop Ru-incorporated bentonite clay as a heterogeneous base catalyst for use in Knoevenagel condensation as an alternative to hazardous base catalysts like pyridine, piperidine, etc., we purify the naturally occurring bentonite clay and Ru3+ cation incorporated into its interlayers of bentonite clay to improve its porosity and to increase the surface area of bentonite clay. Purified bentonite and Ru-bentonite were characterized by FTIR, PXRD, HRTEM, SEM & EDS, BET surface area analysis, and TGA. Base activation was done to these clays and a comparative study of these clays as recyclable heterogeneous catalysts for Knoevenagel Condensation was undertaken in water as a solvent for the chemical transformation of 2,4-dichlorobenzaldehyde and 4-hydroxybenzaldehyde with ethyl cyanoacetate into their corresponding α,β-unsaturated acids. The products were characterized by FTIR, 1H NMR, and 13C NMR analyses. The essential key points of this reaction are mild reaction conditions, absence of hazardous chemicals as used in classical Knoevenagel condensation, reusability of the catalyst, and high yield percentage of the products.
Exploring the Interplay of Physical Environment and Organizational Climate in Sustainable Innovation: A Multidimensional Framework
Authors: Peng Lei , Jia Ruiying 
Published: September 2023

The intricate relationship between physical and social environments within organizations plays a pivotal role in shaping sustainable innovation endeavors. This paper presents a comprehensive analysis of two key dynamics that have garnered substantial scholarly attention for promoting sustainable innovation: the physical environment and the organizational climate. To elucidate the intricate interplay between these dynamics, we propose a novel three-dimensional framework that guides the modeling of the intricate processes through which the physical environment and innovation climate synergistically influence innovation outcomes. Building on this framework, we delve into an in-depth literature review concerning physical environments that exert a significant impact on innovation. Through this review, we identify and elaborate on four pivotal elements of the physical environment: communality, personalization, comfort, and healthiness. Leveraging insights gleaned from this review, we outline two promising avenues for future research in the realm of the physical environment&#039;s interaction with the innovation climate. Furthermore, we underscore the critical importance of adopting an interdisciplinary approach that seamlessly integrates insights from both the physical and social domains to comprehensively understand the sustainable innovation landscape.
Using analogies for introducing synchrotron light in high school
Authors: Acioly Vitor , Neto Telecio Barbosa , Santos Antonio Carlos Fontes dos 
Published: September 2023

The aim of this paper is to propose the use of analogies for teaching principles of synchrotron radiation for high-school students. Analogy is an important tool for teaching new abstract subjects based on familiar content. In this paper, we suggest the use of Teaching With Analogies Strategy (TWAS), which is an approach to overcome the didactic obstacles in introducing abstract physics content to students. The authors expect that this work may contribute to the students' understanding of synchrotron radiation, reflecting the needs and interests of secondary school teachers.
Role of Cu/ZnO nanostructures doping on the optical behavior of polyvinyl alcohol/polyvinyl pyrrolidone/graphene composites for optoelectronic applications
Authors: Althobaiti M. G. , Badawi Ali 
Published: September 2023

Abstract

The linear/nonlinear optical and dielectric performance of PVA/PVP/graphene composites were enhanced by doping with Cu/ZnO (ZCO) nanoparticles (NPs) for optoelectronic applications. Bare and ZCO polymeric nanocomposites (PNCs) blends were fabricated by the casting method. The structure of the synthesized ZCO NPs and ZCO PNCs were studied by X-ray diffraction (XRD) and Fourier transform infra-red (FT-IR) spectroscopy techniques. The optical performance was characterized on the basis of UV-visible-NIR data. The XRD investigations revealed the wurtzite structure of the ZCO NPs with a crystallite size of 17.8 nm. The FT-IR investigations confirmed the integration of ZCO NPs with the host blend’s structure. The optical analysis exposed that the direct and indirect band gap of the host blend decreased from 5.20 eV and 4.94 eV to 4.36 eV and 4.29 eV for 10 wt% of ZCO PNCs. The Urbach energy rose from 0.62 eV to 1.28 eV for 10 wt% of ZCO PNCs. The refractive index grew from 1.29 (bare blend) to 1.82 for 10 wt% of ZCO PNC at hν= 2.0 eV. In addition, a great enhancement in the nonlinear optical constants was achieved via ZCO doping. The third-order nonlinear susceptibility, χ(3), increased from 1.30 x 10-13 esu (bare) to 9.23 x 10-11 esu for 10 wt% of ZCO PNC at hν = 5.0 eV. We suggest these valuable achievements in the optical behavior of PVA/PVP/graphene blend by ZCO doping nominate it for applications in optical devices improvement.
The role of constitutively inactive isoforms of GrsA in regulating the initiation cascade of gramicidin synthesis
Authors: Roy Raktim , Wheatley Brittany , Novick Scott , Murray Daniel , Joseph Newlyn , Dodes-Traian Martin , Griffin Patrick 
Published: September 2023

Abstract
Non-ribosomal Peptide Synthetases (NRPSs) provide exciting targets for templated drug-design because of their assembly-line like mechanism of action. The non-catalytic conformations of the NRPS, GrsA, are proposed to regulate the activation cascade during the synthesis of the antibiotic peptide, Gramicidin. Previous studies hinted at the possibilities of additional, uncharacterized intermediates from the initiation cascade. Here, we redefined the mechanism of catalytic cycle and identified two new structural intermediates showing ‘near-thiolation’ events. The first structural intermediate formed without the need for dissociation of PPi. HDX-MS also revealed a ‘product-release’ intermediate attained solely from the intramolecular allosteric effects of substrate binding at the Adenylation domain. SAXS allowed us to determine the full-length envelope of GrsA for the first time and showed that its resting state is comprised of two inactive conformations. Calorimetry and molecular dynamics simulations provided further evidence supporting a constitutively inactive regulatory framework opening a new paradigm of NRPS research.
Comparison of the prevalence and associated factors of interdialytic fatigue and post-dialysis fatigue among maintenance hemodialysis patients: A cross-sectional study
Authors: Dou jun-kai , Mei Yan , Yang Liang , Liu Huan , Li Li 
Published: September 2023

Abstract
Objective
Interdialytic Fatigue (IDF) and post-dialysis fatigue (PDF) were the most common complication among maintenance hemodialysis (MHD) patients. However, the differences between IDF and PDF in MHD patients have been reported little and their concepts were easy to be confused by some studies. The purpose of this study was to compare the prevalence of fatigue and investigate the differences in the contributing factors between IDF and PDF in patients receiving MHD therapy.
Methods
In this cross-sectional study, 217 MHD patients, from a comprehensive hospital in China, were recruited and collected from January 2022 to June 2022. The Function assessment of Chronic Illness Therapy-Fatigue (FACIT-F) was adopted to measure IDF and PDF. Psychosocial factors included resilience, quality of sleep, and social support which were estimated by the 10-item Connor-Davidson Resilience Scale(CD-RISC), Pittsburgh Sleep Quality Index(PSQI), and Social Support Rate Scale(SSRS), respectively. Multiple logistic regression analyses were performed to identify influencing factors of IDF and PDF in patients on MHD therapy.
Results
The prevalence of IDF and PDF was 29.0% and 61.8%, respectively, and With 96.8% of MHD patients with IDF suffered from PDF. Multiple logistic regression analysis revealed that the independent factors of fatigue were age(p < .001), resilience(p < .001), and sleep quality(p = .001) and age(p = .007), resilience(p < .001), and intradialytic hypotension (IDH) (p < .001) were contributing factors of PDF.
Conclusion
The prevalence of PDF was significantly higher than IDF among MHD patients. Age and resilience were common independent factors of fatigue and PDF.
Live imaging of the airway epithelium reveals that mucociliary clearance modulates SARS-CoV-2 spread
Authors: Hope Thomas , Becker Mark , Martin-Sancho Laura , Simons Lacy , McRaven Michael , Chanda Sumit , Hultquist Judd 
Published: September 2023

Abstract

SARS-CoV-2 initiates infection in the conducting airways, which rely on mucocilliary clearance (MCC) to minimize pathogen penetration. However, it is unclear how MCC impacts SARS-CoV-2 spread after infection is established. To understand viral spread at this site, we performed live imaging of SARS-CoV-2 infected differentiated primary human bronchial epithelium cultures for up to 9 days. Fluorescent markers for cilia and mucus allowed longitudinal monitoring of MCC, ciliary motion, and infection. The number of infected cells peaked at 4 days post-infection in characteristic foci that followed mucus movement. Inhibition of MCC using physical and genetic perturbations limited foci. Later in infection, MCC was diminished despite relatively subtle ciliary function defects. Resumption of MCC and infection spread after mucus removal suggests that mucus secretion mediates this effect. We show that MCC facilitates SARS-CoV-2 spread early in infection while later decreases in MCC inhibit spread, suggesting a complex interplay between SARS-CoV-2 and MCC.