bluuebunny/crossref_metadata_2025_split huggingface dataset:
A core–shell magnet Mn70Bi30 grown at seeds in magnetic fields and its impacts on its spin-dynamics, Curie point and other tailored properties
Authors: Sharma Sanjeev Kumar , Pradhan Debabrata , Ram Shanker 
Published: May 2023

Abstract
The MnBi alloys is a model series of rare-Earth free magnets for surge of technologies of small parts of automobiles, power generators, medical tools, memory systems, and many others. The magnetics stem primarily at unpaired Mn-3d5 spins (a 4.23 μ
B moment) align parallel via an orbital moment 0.27 μ
B of Bi-5d106s2p3 in a crystal lattice. Thus, using a surplus Mn (over Bi) in a Mn70Bi30 type alloy designs a spin-rich system of duly tailored properties useful for magnetics and other devices. In this view, we report here a strategy of a refined alloy powder Mn70Bi30 can grow into small crystals of hexagonal (h) plates at seeds as annealed in magnetic fields (in H2 gas). So, small h-plates (30 to 50 nm widths) are grown up at (002) facets, wherein the edges are turned down in a spiral (≤2.1 nm thicknesses) in a core–shell structure. The results are described with x-ray diffraction, lattice images and magnetic properties of a powder Mn70Bi30 (milled in glycine) is annealed at 573 K for different time periods, so to the Mn/Bi order at the permeable facets (seeds). Duly annealed samples exhibit an enhanced magnetization, M
s → 70.8 emu g−1, with duly promoted coercivity H
c → 10.810 kOe (15.910 kOe at 350 K), energy–product 14.8 MGOe, and the crystal-field-anisotropy, K
1 → 7.6 × 107 erg cm−3, reported at room temperature. Otherwise, M
s should decline at any surplus 3d5-Mn spins order antiparallel at the antisites. Enhanced Curie point 658.1 K (628 K at Mn50Bi50 alloy) anticipates that a surplus Mn does favor the Mn–Bi exchange interactions. Proposed spin models well describe the spin-dynamics and lattice relaxations (on anneals) over the lattice volume (with twins) and spin clusters.
The early heading growth stage of rice plants in using the SRI method by giving liquid organic fertilizer of coconut husk and banana stems
Authors: Rozen N , Kasim M , Kusumawati A , Ikram H , Sholihat I 
Published: May 2023

Abstract
Coconut husk and banana stem waste can be used as a source of organic material for plants which is utilized in the form of liquid organic fertilizer. This study aims to determine the interaction between types of liquid organic fertilizer and the concentration of liquid organic fertilizer. This research was carried out in Sungai Bangek, Balai Gadang Village, Koto Tangah District, Padang City from June until September 2022. The design used was a split plot in a randomized block design. The main plot is liquid organic fertilizer with 2 levels of coconut husk and banana stem while the subplot is liquid organic fertilizer concentration consisting of 7 levels (0, 50, 100, 150, 200, 250, 300 ml/liter). The data were analyzed through variance analysis using the F test and if significant, it was continued with Duncan New Multiple Range Test (DNMRT) with a significance level of 5%. The data is processed with Stat8 software. The observed variables consisted of plant height, the number of tillers, leaf area index, relative growth rate, and net assimilation rate. The results obtained on the growth variable have not shown significant results in every observed observation. There was a very strong correlation between the number of tillers and the leaf area index which had a unidirectional relationship. There was a fairly strong correlation between the leaf area index and net assimilation rate which has an opposite relationship.
Preliminary results of the scale insects (Hemiptera: Sternorryncha) exploration from West Halmahera, in the Eastern Weber line of Wallacea
Authors: Hidayat P , Subagyo V N O , Maharani Y , Puspasari L T , Encilia  , Suwito A , Fara S B 
Published: May 2023

Abstract
Exploration of scale insects was done in West Halmahera, North Maluku, from May to June 2022 using purposive sampling as many 7,261 individual scale insects, which consist of six families, were collected. Basic information was recorded, such as pictures of insects, host plants, and GPS coordinates. Identification to species level is still ongoing by morphological characters using slide mounting specimens and the mtCO-I DNA sequencing. It is expected to have several new reports on insect species, host plants, and possibly new species. The information will enrich the record of fauna diversity in Indonesia and be useful for agriculture, especially in pest management.
Testing Theory-Based Messages to Encourage Women at Average Risk for Breast Cancer to Consider Biennial Mammography Screening
Authors: Guan Yue , Haardörfer Regine , McBride Colleen M , Escoffery Cam , Lipscomb Joseph 
Published: May 2023

Abstract

Background
The US Preventive Services Task Force does not recommend routine annual mammography screening for women aged 40–49 at average risk. Little research has been done to develop theory-based communication interventions to facilitate informed decision-making about reducing potentially low-value mammography screening.

Purpose
Evaluate the effects of theory-based persuasive messages on women’s willingness to consider delaying screening mammography until age 50 or have mammograms biennially.

Methods
We conducted a randomized controlled communication experiment online with a population-based sample of U.S. women aged 40–49 (N = 383) who screened to be at average risk for breast cancer. Women were randomly assigned to the following messaging summaries: annual mammography risks in 40s (Arm 1, n = 124), mammography risks plus family history-based genetic risk (Arm 2, n = 120), and mammography risks, genetic risk, and behavioral alternatives (Arm 3, n = 139). Willingness to delay screening or reduce screening frequency was assessed post-experiment by a set of 5-point Likert scale items.

Results
Women in Arm 3 reported significantly greater willingness to delay screening mammography until age 50 (mean = 0.23, SD = 1.26) compared with those in Arm 1 (mean = −0.17, SD = 1.20; p = .04). There were no significant arm differences in willingness to reduce screening frequency. Exposure to the communication messages significantly shifted women’s breast cancer-related risk perceptions without increasing unwarranted cancer worry across all three arms.

Conclusions
Providing women with screening information and options may help initiate challenging discussions with providers about potentially low-value screening.
ATTIC is an integrated approach for predicting A-to-I RNA editing sites in three species
Authors: Chen Ruyi , Li Fuyi , Guo Xudong , Bi Yue , Li Chen , Pan Shirui , Coin Lachlan J M , Song Jiangning 
Published: May 2023

Abstract
A-to-I editing is the most prevalent RNA editing event, which refers to the change of adenosine (A) bases to inosine (I) bases in double-stranded RNAs. Several studies have revealed that A-to-I editing can regulate cellular processes and is associated with various human diseases. Therefore, accurate identification of A-to-I editing sites is crucial for understanding RNA-level (i.e. transcriptional) modifications and their potential roles in molecular functions. To date, various computational approaches for A-to-I editing site identification have been developed; however, their performance is still unsatisfactory and needs further improvement. In this study, we developed a novel stacked-ensemble learning model, ATTIC (A-To-I ediTing predICtor), to accurately identify A-to-I editing sites across three species, including Homo sapiens, Mus musculus and Drosophila melanogaster. We first comprehensively evaluated 37 RNA sequence-derived features combined with 14 popular machine learning algorithms. Then, we selected the optimal base models to build a series of stacked ensemble models. The final ATTIC framework was developed based on the optimal models improved by the feature selection strategy for specific species. Extensive cross-validation and independent tests illustrate that ATTIC outperforms state-of-the-art tools for predicting A-to-I editing sites. We also developed a web server for ATTIC, which is publicly available at http://web.unimelb-bioinfortools.cloud.edu.au/ATTIC/. We anticipate that ATTIC can be utilized as a useful tool to accelerate the identification of A-to-I RNA editing events and help characterize their roles in post-transcriptional regulation.
Identification of representative species-specific genes for abundance measurements
Authors: Zachariasen Trine , Petersen Anders Østergaard , Brejnrod Asker , Vestergaard Gisle Alberg , Eklund Aron , Nielsen Henrik Bjørn 
Published: May 2023

Abstract

Motivation
Metagenomic binning facilitates the reconstruction of genomes and identification of Metagenomic Species Pan-genomes or Metagenomic Assembled Genomes. We propose a method for identifying a set of de novo representative genes, termed signature genes, which can be used to measure the relative abundance and used as markers of each metagenomic species with high accuracy.

Results
An initial set of the 100 genes that correlate with the median gene abundance profile of the entity is selected. A variant of the coupon collector’s problem was utilized to evaluate the probability of identifying a certain number of unique genes in a sample. This allows us to reject the abundance measurements of strains exhibiting a significantly skewed gene representation. A rank-based negative binomial model is employed to assess the performance of different gene sets across a large set of samples, facilitating identification of an optimal signature gene set for the entity. When benchmarked the method on a synthetic gene catalog, our optimized signature gene sets estimate relative abundance significantly closer to the true relative abundance compared to the starting gene sets extracted from the metagenomic species. The method was able to replicate results from a study with real data and identify around three times as many metagenomic entities.

Availability and implementation
The code used for the analysis is available on GitHub: https://github.com/trinezac/SG_optimization.

Supplementary information
Supplementary data are available at Bioinformatics Advances online.
STEMSIM: a simulator of within-strain short-term evolutionary mutations for longitudinal metagenomic data
Authors: Zhou Boyan , Li Huilin 
Published: May 2023

Abstract

Motivation
As the resolution of metagenomic analysis increases, the evolution of microbial genomes in longitudinal metagenomic data has become a research focus. Some software has been developed for the simulation of complex microbial communities at the strain level. However, the tool for simulating within-strain evolutionary signals in longitudinal samples is still lacking.

Results
In this study, we introduce STEMSIM, a user-friendly command-line simulator of short-term evolutionary mutations for longitudinal metagenomic data. The input is simulated longitudinal raw sequencing reads of microbial communities or single species. The output is the modified reads with within-strain evolutionary mutations and the relevant information of these mutations. STEMSIM will be of great use for the evaluation of analytic tools that detect short-term evolutionary mutations in metagenomic data.

Availability and implementation
STEMSIM and its tutorial are freely available online at https://github.com/BoyanZhou/STEMSim.
GTExVisualizer: a web platform for supporting ageing studies
Authors: Guzzi Pietro Hiram , Lomoio Ugo , Veltri Pierangelo 
Published: May 2023

Abstract

Motivation
Studying ageing effects on molecules is an important new topic for life science. To perform such studies, the need for data, models, algorithms, and tools arises to elucidate molecular mechanisms. GTEx (standing for Genotype-Tissue Expression) portal is a web-based data source allowing to retrieve patients’ transcriptomics data annotated with tissues, gender, and age information. It represents the more complete data sources for ageing effects studies. Nevertheless, it lacks functionalities to query data at the sex/age level, as well as tools for protein interaction studies, thereby limiting ageing studies. As a result, users need to download query results to proceed to further analysis, such as retrieving the expression of a given gene on different age (or sex) classes in many tissues.

Results
We present the GTExVisualizer, a platform to query and analyse GTEx data. This tool contains a web interface able to: (i) graphically represent and study query results; (ii) analyse genes using sex/age expression patterns, also integrated with network-based modules; and (iii) report results as plot-based representation as well as (gene) networks. Finally, it allows the user to obtain basic statistics which evidence differences in gene expression among sex/age groups.

Conclusion
The GTExVisualizer novelty consists in providing a tool for studying ageing/sex-related effects on molecular processes.

Availability and implementation
GTExVisualizer is available at: http://gtexvisualizer.herokuapp.com. The source code and data are available at: https://github.com/UgoLomoio/gtex_visualizer.
Aerobic exercises regulate the epididymal anion homeostasis of high-fat diet-induced obese rats through TRPA1-mediated Cl− and HCO3− secretion
Authors: Gao Dong-Dong , Ding Nan , Deng Wei-Ji , Li Pei-Lun , Chen Yi-Lin , Guo Lian-Meng , Liang Wen-Hao , Zhong Jia-Hui , Liao Jing-Wen , Huang Jun-Hao , Hu Min 
Published: May 2023

Abstract
Aerobic exercises could improve the sperm motility of obese individuals. However, the underlying mechanism has not been fully elucidated, especially the possible involvement of the epididymis in which sperm acquire their fertilizing capacity. This study aims to investigate the benefit effect of aerobic exercises on the epididymal luminal milieu of obese rats. Sprague–Dawley male rats were fed on a normal or high-fat diet (HFD) for 10 weeks and then subjected to aerobic exercises for 12 weeks. We verified that TRPA1 was located in the epididymal epithelium. Notably, aerobic exercises reversed the downregulated TRPA1 in the epididymis of HFD-induced obese rats, thus improving sperm fertilizing capacity and Cl− concentration in epididymal milieu. Ussing chamber experiments showed that cinnamaldehyd (CIN), agonist of TRPA1, stimulated an increase of the short-circuit current (ISC) in rat cauda epididymal epithelium, which was subsequently abolished by removing the ambient Cl− and HCO3−. In vivo data revealed that aerobic exercises increased the CIN-stimulated Cl− secretion rate of epididymal epithelium in obese rats. Pharmacological experiments revealed that blocking cystic fibrosis transmembrane regulator (CFTR) and Ca2+-activated Cl− channel (CaCC) suppressed the CIN-stimulated anion secretion. Moreover, CIN application in rat cauda epididymal epithelial cells elevated intracellular Ca2+ level, and thus activate CACC. Interfering with the PGHS2-PGE2-EP2/EP4-cAMP pathway suppressed CFTR-mediated anion secretion. This study demonstrates that TRPA1 activation can stimulate anion secretion via CFTR and CaCC, which potentially forming an appropriate microenvironment essential for sperm maturation, and aerobic exercises can reverse the downregulation of TRPA1 in the epididymal epithelium of obese rats.
OC-006 INTRAOPERATIVE FASCIA TRACTION FOR THE TREATMENT OF LARGE ABDOMINAL WALL/INCISIONAL HERNIAS (W3, EHS)
Authors: Niebuhr H , Dag H , Reinpold W 
Published: May 2023

Abstract

Aim
To evaluate the effectiveness, clinical practicability, and complication rate of the fascial traction procedure for the treatment of large ventral hernias.

Method
This observational study evaluated 90 patients from 1 specialised center with an intraoperatively measured fascial distance of more than 10 cm who were treated by Intraoperative Fascia Traction – IFT- (abdominal wall stretching) using the fasciotens® hernia traction procedure.

Results
Fascial gap measured pre-operatively ranged from 10 to 44 cm, with most patients (94%) having a fascial above 15 cm (W3 according to the European Hernia Society classification). The mean fascial distance was reduced from 16.1 ± 0.8 to 5.8 ± 0.7 cm (stretch gain 10.2 ± 0.7 cm, p &lt; 0.0001, Wilcoxon matched-pairs signed-ranks test). A reduction in fascial distance of at minimum 50% was achieved in three quarters of the patients, and in half of the treated patients the reduction in fascial distance amounted to even more than 70% The closure rate achieved by fascial traction after a mean surgical duration of 207.3 ± 11.0 minutes was 90% (81/90).
Postoperative complications occurred in 7 patients (8%). Re-operation was required in 4 patients (4.5%).

Conclusion
This described intraoperative fascia traction (IFT) method is a new, promising procedure for abdominal wall closure in large ventral hernias. The presented results demonstrate a high effectiveness, a good clinical practicability and a low complication rate of the
Intraoperative fascia traction (IFT) method.
OC-012 NATIONWIDE ANALYSIS OF SHORT-TERM OUTCOMES AFTER LAPAROSCOPIC IPOM VS. ROBOT-ASSISTED RETROMUSCULAR REPAIR OF SMALL TO MEDIUM VENTRAL HERNIA
Authors: Jensen K K , Helgstrand F , Henriksen N A 
Published: May 2023

Abstract

Aim
With the introduction of a robot-assisted approach, retromuscular mesh placement is technically more feasible compared to laparoscopic IPOM, with potential gains for the patient, including avoidance of painful mesh fixation and intraperitoneal mesh placement. We aimed to examine the short-term outcomes after laparoscopic intraperitoneal onlay mesh (IPOM) compared to robot-assisted retromuscular repair of small to medium sized ventral hernia.

Material & Methods
This was a nationwide cohort study of all patients undergoing either laparoscopic IPOM or robot-assisted retromuscular repair of a ventral hernia with a horizontal fascial defect &lt;7 cm in the period 2017 to 2022. Outcomes included postoperative hospital length of stay, 90-day readmission, and 90-day operative reintervention, and multivariable logistic regression analysis was performed to adjust for the relevant confounder.

Results
A total of 2,453 patients were included for analysis, of which 389 patients underwent robot-assisted retromuscular hernia repair and 2,064 laparoscopic IPOM repair.
The rate of IPOM repaired patients hospitalized more than 2 days was 4 times higher than after robotic retromuscular repair (18.2% vs. 4.5%, P &lt; 0.001). The incidence of readmission within 90 days postoperatively was significantly higher after laparoscopic IPOM repair (10.9% vs. 6.7%, P = 0.016). There was no difference in the incidence of patients undergoing operative intervention within the first 90 days postoperatively (laparoscopic IPOM 1.8% vs. robot-assisted retromuscular 1.3%, P = 0.579).

Conclusions
Robot-assisted retromuscular ventral hernia repair was associated with a significantly reduced incidence of prolonged length of postoperative hospital stay and risk of 90-day compared to laparoscopic IPOM.
OC-013 MEDIUM-LONG TERM OUTCOMES OF RETROMUSCULAR PARASTOMAL HERNIA REPAIR WITH PAULI MODIFIED SUGAR BARKER PROCEDURE
Authors: Martínez Caballero J , Román García De León L , Medina Pedrique M , Avilés Oliveros A , Morejón Ruiz S , Pérez-Flecha González M , Robin Valle Del Lersundi A , Rodríguez Muñoz J , López Monclús J , Blazquez Hernando L A , García Ureña M Á 
Published: May 2023

Abstract

Objective
We aim to evaluate the outcomes and stoma complication in parastomal hernia repair (PHR) with Pauli procedure.

Material and Methods
18 patients were recruited between 2015–2022 in 2 hospitals. Data were obtained from prospective clinical database. Surgical technique included: posterior component separation (TAR), bowel lateralization according to Pauli modified Sugarbaker and, if necessary, stoma relocation. Quantitative variables are shown as median [interquartile rank] and qualitative as percentage.

Results
22.2% patients had recurrent PH with 2 [3] previous repair attempts. 22.2% underwent bilateral TAR and 11.1% required inlay mesh. Panniculectomy was performed in 17,8% of patients and stoma relocation in 44,4%; 17% required intestinal resection and 11,1% bowel suturing.
Complications &lt; 30days: 17% had surgical site infection (SSIs), 2 deep SSIs and one required surgical management. 22.2% had clinical seroma, one required percutaneous drainage and other surgical intervention. Postoperative complications were adynamic ileus (22,2%), bowel obstruction (5%) which was managed conservatively and anastomotic leakage (5%). No mortality was observed, and hospital-stay length was 8 [7.25] days.
Complications &gt; 30days: 5.5% chronic seroma (grade III), 5.5% PTE and 22.2% bowel obstruction of which one required adhesiolysis and another bowel resection.
27.8% had any stoma-related complication: partial ischemia (5.5%), retraction (11.1%), prolapse (5.5%) and obstruction (5.5%) managed conservatively. One patient required reoperation due to stoma perforation. We found 25% of clinical or radiological recurrence after 24 [20.1] months follow-up.

Conclusion
This technique provides acceptable recurrence rates of the PH, but is still high, with a non-negligible associated comorbidity.
OC-041 TOTALLY EXTRA-PERITONEAL REPAIR VERSUS TRANS-ABDOMINAL PRE-PERITONEAL REPAIR FOR THE LAPAROSCOPIC SURGICAL MANAGEMENT OF SPORTSMAN'S HERNIA: A SYSTEMATIC REVIEW AND META-ANALYSIS
Authors: Kler A , Sekhon N , Antoniou G , Satyadas T 
Published: May 2023

Abstract

Aim
Open and laparoscopic modalities are employed for treatment of sportsman's hernia, with totally extra-peritoneal (TEP) and trans-abdominal pre-peritoneal (TAPP) laparoscopic approaches both currently being utilised. At present, neither subtype has demonstrated superiority for sportsman's hernia repair. The aim of this review was to evaluate current evidence to ascertain whether there was a difference in laparoscopic techniques following sportsman's hernia repair.

Material & Methods
A systematic literature search was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement standards. Databases searched included PubMed, Scopus and Web of Science to identify all randomised controlled trials (RCTs) and observational studies. Risk of bias was assessed using the Cochrane risk of bias tool and Newcastle-Ottawa scale for RCTs and observational studies, respectively. The assessed outcomes included median time to return to sporting activity, complications and the degree of postoperative pain reduction within three months. Random effects model was used to calculate pooled proportion data where feasible. Subgroup analyses were also performed.

Results
28 studies were identified including 2 RCTs and 26 observational studies. No significant differences were observed between techniques in the primary or secondary outcomes. Significant heterogeneity was observed in all outcomes. This was signficant for return to sporting activity; thus meta-analysis was not feasible in this domain. Median time to return to sporting activity was 28 days for both techniques.

Conclusions
There is no difference in the primary and secondary outcomes in either technique. An RCT comparing TEP and TAPP repair is needed to provide definitive data.