bluuebunny/crossref_metadata_2025_split huggingface dataset:
Distributed event‐triggered control for bipartite consensus under complex cyber‐attacks
Authors: Wu Tong , Cai Guangbin , Wang Jie , Mu Chaoxu 
Published: March 2023

AbstractSince complex cyber‐attacks and inter‐agent competition pose security risks to multi‐agent systems (MASs), the problem of bipartite consensus control under complex cyber‐attacks studied in this article is more challenging and practical than normal consensus. Firstly, a sliding surface for designing control inputs is presented to overcome the effects of external disturbances and false data injection attacks. The event‐triggered mechanism is constructed to reduce control consumption, and the avoidance of Zeno behavior is demonstrated by analyzing the trigger interval lower bound. Then, considering the existence of aperiodic denial‐of‐service (DoS) attacks, the attack model is analyzed in detail, and the stability of the MAS under complex cyber‐attacks is proved by adopting an inductive way and selecting an appropriate Lyapunov function. Finally, the effectiveness of the presented event‐based control protocol can be seen by simulation.
Implementation of sustainable development goal 8 in European Union countries–A measurement concept and a multivariate comparative analysis
Authors: Grzebyk Mariola , Stec Małgorzata , Hejdukova Pavlina 
Published: March 2023

AbstractThe study attempts to determine a synthetic measure of the level of implementation of Sustainable Development Goal 8 related to promote sustained, inclusive and sustainable economic growth, full and productive employment and decent work for all and conducts a multivariate comparative analysis of EU countries in terms of its implementation. The statistical database contained all 9 variables characterising this goal, collected for 27 EU countries in the period from 2015 to 2020. The research method used was the method of unitarisation zeroed in the dynamic version. The results of the conducted research confirm that there have been positive changes in the implementation of SDG 8 sustainable development in most EU countries in the examined years. This is indicated by the increasing values of the calculated synthetic measure for individual EU27 countries in the examined years. However, in the last examined year, i.e. 2020, the impact of the crisis caused by the COVID 19 pandemic on the achievement of the examined Sustainable Development Goal was observed. In 2020, compared to 2015, 12 EU countries advanced their positions in the EU27 ranking, 3 countries did not change their positions, while 12 countries dropped down in the ranking. The study also assesses two selected EU countries, namely the Czech Republic and Poland (The Czech Republic and Poland are the countries of origin of the authors of this article, with a similar history, located in Central and Eastern Europe and with similar problems of socio‐economic development. These countries also joined the European Union in the same year, 2004) in terms of achieving Sustainable Development Goal 8.
Boosting multivariate structured additive distributional regression models
Authors: Strömer Annika , Klein Nadja , Staerk Christian , Klinkhammer Hannah , Mayr Andreas 
Published: March 2023

We develop a model‐based boosting approach for multivariate distributional regression within the framework of generalized additive models for location, scale, and shape. Our approach enables the simultaneous modeling of all distribution parameters of an arbitrary parametric distribution of a multivariate response conditional on explanatory variables, while being applicable to potentially high‐dimensional data. Moreover, the boosting algorithm incorporates data‐driven variable selection, taking various different types of effects into account. As a special merit of our approach, it allows for modeling the association between multiple continuous or discrete outcomes through the relevant covariates. After a detailed simulation study investigating estimation and prediction performance, we demonstrate the full flexibility of our approach in three diverse biomedical applications. The first is based on high‐dimensional genomic cohort data from the UK Biobank, considering a bivariate binary response (chronic ischemic heart disease and high cholesterol). Here, we are able to identify genetic variants that are informative for the association between cholesterol and heart disease. The second application considers the demand for health care in Australia with the number of consultations and the number of prescribed medications as a bivariate count response. The third application analyses two dimensions of childhood undernutrition in Nigeria as a bivariate response and we find that the correlation between the two undernutrition scores is considerably different depending on the child's age and the region the child lives in.
Carbon Dots: Classically Defined versus Organic Hybrids on Shared Properties, Divergences, and Myths
Authors: Liang Weixiong , Sonkar Sumit Kumar , Saini Deepika , Sheriff Kirkland , Singh Buta , Yang Liju , Wang Ping , Sun Ya‐Ping 
Published: March 2023

AbstractCarbon dots are defined as small carbon nanoparticles with effective surface passivation via organic functionalization. The definition is literally a description of what carbon dots are originally found for the functionalized carbon nanoparticles displaying bright and colorful fluorescence emissions, mirroring those from similarly functionalized defects in carbon nanotubes. In literature more popular than classical carbon dots are the diverse variety of dot samples from “one‐pot” carbonization of organic precursors. On the two different kinds of samples from the different synthetic approaches, namely, the classical carbon dots versus those from the carbonization method, highlighted in this article are their shared properties and apparent divergences, including also explorations of the relevant sample structural and mechanistic origins for the shared properties and divergences. Echoing the growing evidence and concerns in the carbon dots research community on the major presence of organic molecular dyes/chromophores in carbonization produced dot samples, demonstrated and discussed in this article are some representative cases of dominating spectroscopic interferences due to the organic dye contamination that have led to unfound claims and erroneous conclusions. Mitigation strategies to address the contamination issues, including especially the use of more vigorous processing conditions in the carbonization synthesis, are proposed and justified.
Enzyme‐Activatable Polypeptide for Plasma Membrane Disruption and Antitumor Immunity Elicitation
Authors: Liu Jiahui , Li Rong Sheng , Zhang Lei , Wang Jie , Dong Qi , Xu Zhigang , Kang Yuejun , Xue Peng 
Published: March 2023

AbstractEnzyme‐instructed self‐assembly of bioactive molecules into nanobundles inside cells is conceived to potentially disrupt plasma membrane and subcellular structure. Herein, an alkaline phosphatase (ALP)‐activatable hybrid of ICG‐CF4KYp is facilely synthesized by conjugating photosensitizer indocyanine green (ICG) with CF4KYp peptide via classical Michael addition reaction. ALP‐induced dephosphorylation of ICG‐CF4KYp enables its transformation from small‐molecule precursor into rigid nanofibrils, and such fibrillation in situ causes severe mechanical disruption of cytomembrane. Besides, ICG‐mediated photosensitization causes additional oxidative damage of plasma membrane by lipid peroxidation. Hollow MnO2 nanospheres devote to deliver ICG‐CF4KYp into tumorous tissue through tumor‐specific acidity/glutathione‐triggered degradation of MnO2, which is monitored by fluorescent probing and magnetic resonance imaging. The burst release of damage‐associated molecular patterns and other tumor antigens during therapy effectively triggers immunogenetic cell death and improves immune stimulatory, as demonstrated by the promotion of dendritic cell maturation and CD8+ lymphocyte infiltration, as well as constraint of regulatory T cell population. Taken together, such cytomembrane injury strategy based on peptide fibrillation in situ holds high clinical promise for lesion‐specific elimination of primary, abscopal, and metastatic tumors, which may enlighten more bioinspired nanoplatforms for anticancer theranostics.
Promising Mass‐Productive 4‐Inch Commercial SERS Sensor with Particle in Micro‐Nano Porous Ag/Si/Ag Structure Using in Auxiliary Diagnosis of Early Lung Cancer
Authors: Gao Yuanmei , Zhu Hongyu , Wang Xiaoxiong , Shen Rong , Zhou Xiaoming , Zhao Xiaofei , Li Zhen , Zhang Chao , Lei Fengcai , Yu Jing 
Published: March 2023

AbstractThe construction of commercial surface enhanced Raman scattering (SERS) sensors suitable for clinical applications is a pending problem, which is heavily limited by the low production of high‐performance SERS bases, because they usually require fine or complicated micro/nano structures. To solve this issue, herein, a promising mass‐productive 4‐inch ultrasensitive SERS substrate available for early lung cancer diagnosis is proposed, which is designed with a special architecture of particle in micro‐nano porous structure. Benefitting from the effective cascaded electric field coupling inside the particle‐in‐cavity structure and efficient Knudsen diffusion of molecules within the nanohole, the substrate exhibits remarkable SERS performance for gaseous malignancy biomarker, with the limit of detection is 0.1 ppb and the average relative standard deviation value at different scales (from cm2 to µm2) is ≈16.5%. In practical application, this large‐sized sensor can be further divided into small ones (1 × 1 cm2), and more than 65 chips will be obtained from just one 4‐inch wafer, greatly increasing the output of commercial SERS sensor. Further, a medical breath bag composed of this small chip is designed and studied in detail here, which suggested high‐specificity recognition for lung cancer biomarker in mixed mimetic exhalation tests.
Improving Out‐of‐Plane Charge Mobility and Phase Stability of Dion‐Jacobson Lead‐Free Perovskites via Intercalating π‐Conjugated Aromatic Spacers
Authors: Sun Qian , Shang Ming‐Hui , Fang Zhi , Zheng Yapeng , Hou Xinmei , Yang Weiyou 
Published: March 2023

AbstractThe layered quasi‐2D perovskites are recognized as one of the effective strategies to resolve the big problem of intrinsic phase instability of the perovskites. However, in such configurations, their performance is fundamentally limited due to the correspondingly weakened out‐of‐plane charge mobility. Herein, the π‐conjugated p‐phenylenediamine (PPDA) is introduced as organic ligand ions for rationally designing lead‐free and tin‐based 2D perovskites with the aid of theoretical computation. It is evidenced that both out‐of‐plane charge transport capacity and stability can be significantly enhanced within as‐established quasi‐2D Dion‐Jacobson (DJ) (PPDA)Csn‐1SnnI3n+1 perovskites. The obviously increased electrical conductivity and reduced carrier effective masses are attributed to the enhanced interlayer interactions, limited structural distortions of diamine cations, as well as improved orbital coupling between Sn2+ and I− ions of (PPDA)Csn‐1SnnI3n+1 perovskites. Accordingly, by dimension engineering of the inorganic layer (n), the bandgap (Eg) of quasi‐2D perovskites can be linearly tailored toward the suitable Eg (1.387 eV) with optimal photoelectric conversion efficiency (PCE) of 18.52%, representing their great potential toward promising applications in advanced solar cells.
Tailor‐Made Autophagy Cascade Amplification Polymeric Nanoparticles for Enhanced Tumor Immunotherapy
Authors: Long Xuehua , Wang Huiqi , Yan Jianqin , Li Yifei , Dong Xue , Tian Sijia , Sun Yong , Luo Kui , He Bin , Liang Yan 
Published: March 2023

AbstractChemotherapeutics can induce immunogenic cell death (ICD) by triggering autophagy and mediate antitumor immunotherapy. However, using chemotherapeutics alone can only cause mild cell‐protective autophagy and be incapable of inducing sufficient ICD efficacy. The participation of autophagy inducer is competent to enhance autophagy, so the level of ICD is promoted and the effect of antitumor immunotherapy is highly increased. Herein, tailor‐made autophagy cascade amplification polymeric nanoparticles STF@AHPPE are constructed to enhance tumor immunotherapy. Arginine (Arg), polyethyleneglycol–polycaprolactone, and epirubicin (EPI) are grafted onto hyaluronic acid (HA) via disulfide bond to form the AHPPE nanoparticles and autophagy inducer STF‐62247 (STF) is loaded. When STF@AHPPE nanoparticles target to tumor tissues and efficiently enter into tumor cells with the help of HA and Arg, the high glutathione concentration leads to the cleavage of disulfide bond and the release of EPI and STF. Finally, STF@AHPPE induces violent cytotoxic autophagy and strong ICD efficacy. As compared to AHPPE nanoparticles, STF@AHPPE nanoparticles kill the most tumor cells and show the more obvious ICD efficacy and immune activation ability. This work provides a novel strategy for combining tumor chemo‐immunotherapy with autophagy induction.
Scalable Manufacturing of Environmentally Stable All‐Solid‐State Plant Protein‐Based Supercapacitors with Optimal Balance of Capacitive Performance and Mechanically Robust
Authors: Jiang Shuaicheng , Wei Yanqiang , Li Xiaona , Shi Sheldon Q. , Tian Dan , Fang Zhen , Li Jianzhang 
Published: March 2023

AbstractThe development of advanced biomaterial with mechanically robust and high energy density is critical for flexible electronics, such as batteries and supercapacitors. Plant proteins are ideal candidates for making flexible electronics due to their renewable and eco‐friendly natures. However, due to the weak intermolecular interactions and abundant hydrophilic groups of protein chains, the mechanical properties of protein‐based materials, especially in bulk materials, are largely constrained, which hinders their performance in practical applications. Here, a green and scalable method is shown for the fabrication of advanced film biomaterials with high mechanical strength (36.3 MPa), toughness (21.25 MJ m−3), and extraordinary fatigue‐resistance (213 000 times) by incorporating tailor‐made core–double‐shell structured nanoparticles. Subsequently, the film biomaterials combine to construct an ordered, dense bulk material by stacking‐up and hot‐pressing techniques. Surprisingly, the solid‐state supercapacitor based on compacted bulk material shows an ultrahigh energy density of 25.8 Wh kg−1, which is much higher than those previously reported advanced materials. Notably, the bulk material also demonstrates long‐term cycling stability, which can be maintained under ambient condition or immersed in H2SO4 electrolyte for more than 120 days. Thus, this research improves the competitiveness of protein‐based materials for real‐world applications such as flexible electronics and solid‐state supercapacitors.
Understanding the Role of (W, Mo, Sb) Dopants in the Catalyst Evolution and Activity Enhancement of Co3O4 during Water Electrolysis via In Situ Spectroelectrochemical Techniques
Authors: Tran‐Phu Thanh , Chatti Manjunath , Leverett Joshua , Nguyen Thi Kim Anh , Simondson Darcy , Hoogeveen Dijon A , Kiy Alexander , Duong The , Johannessen Bernt , Meilak Jaydon , Kluth Patrick , Amal Rose , Simonov Alexandr N. , Hocking Rosalie K. , Daiyan Rahman , Tricoli Antonio 
Published: March 2023

AbstractUnlocking the potential of the hydrogen economy is dependent on achieving green hydrogen (H2) production at competitive costs. Engineering highly active and durable catalysts for both oxygen and hydrogen evolution reactions (OER and HER) from earth‐abundant elements is key to decreasing costs of electrolysis, a carbon‐free route for H2 production. Here, a scalable strategy to prepare doped cobalt oxide (Co3O4) electrocatalysts with ultralow loading, disclosing the role of tungsten (W), molybdenum (Mo), and antimony (Sb) dopants in enhancing OER/HER activity in alkaline conditions, is reported. In situ Raman and X‐ray absorption spectroscopies, and electrochemical measurements demonstrate that the dopants do not alter the reaction mechanisms but increase the bulk conductivity and density of redox active sites. As a result, the W‐doped Co3O4 electrode requires ≈390 and ≈560 mV overpotentials to reach ±10 and ±100 mA cm−2 for OER and HER, respectively, over long‐term electrolysis. Furthermore, optimal Mo‐doping leads to the highest OER and HER activities of 8524 and 634 A g−1 at overpotentials of 0.67 and 0.45 V, respectively. These novel insights provide directions for the effective engineering of Co3O4 as a low‐cost material for green hydrogen electrocatalysis at large scales.
Metal‐Organic Framework Materials in Perovskite Solar Cells: Recent Advancements and Perspectives
Authors: Ye Yuxuan , Yin Yongqi , Chen Yan , Li Shuang , Li Lin , Yamauchi Yusuke 
Published: March 2023

AbstractOrganic–inorganic hybrid perovskite solar cells (PSCs) are among the most promising candidates for the next generation of photovoltaic devices because of the significant increase in their power conversion efficiency (PCE) from less than 10% to 25.7% in past decade. The metal‐organic framework (MOF) materials owing to their unique properties, such as large specific surface area, abundant binding sites, adjustable nanostructures, and synergistic effects, are used as additives or functional layers to enhance the device performance and long‐term stability of PSCs. This review focuses on the recent advancements in the applications of MOFs as/in different functional layers of PSCs. The photovoltaic performance, impact, and advantages of MOF materials integrated into the perovskite absorber, electron transport layer, hole transport layer, and interfacial layer are reviewed. In addition, the applicability of MOFs to mitigate leakage of Pb2+ from halide perovskites and corresponding devices is discussed. This review concludes with the perspectives on further research directions for employing MOFs in PSCs.
Thyroid‐Friendly Soft Materials as 3D Cell Culture Tool for Stimulating Thyroid Cell Function
Authors: Jun Indong , Cho Hyunki , Amos Sebastian E. , Choi Youngjun , Choi Yu Suk , Ryu Chang Seon , Lee Sang‐Ah , Han Dong‐Wook , Han Hyung‐Seop , Yang Ji Hun , Jeong Hyun‐Woo , Park Honghyun , Kim Young Jun 
Published: March 2023

AbstractThe disruption of thyroid hormones because of chemical exposure is a significant societal problem. Chemical evaluations of environmental and human health risks are conventionally based on animal experiments. However, owing to recent breakthroughs in biotechnology, the potential toxicity of chemicals can now be evaluated using 3D cell cultures. In this study, the interactive effects of thyroid‐friendly soft (TS) microspheres on thyroid cell aggregates are elucidated and their potential as a reliable toxicity assessment tool is evaluated. Using state‐of‐the‐art characterization methods coupled with cell‐based analysis and quadrupole time‐of‐flight mass spectrometry, it is shown that TS‐microsphere‐integrated thyroid cell aggregates exhibit improved thyroid function. Specifically, the responses of zebrafish embryos, which are used for thyroid toxicity analysis, and the TS‐microsphere‐integrated cell aggregates to methimazole (MMI), a known thyroid inhibitor, are compared. The results show that the thyroid hormone disruption response of the TS‐microsphere‐integrated thyroid cell aggregates to MMI is more sensitive compared with those of the zebrafish embryos and conventionally formed cell aggregates. This proof‐of‐concept approach can be used to control cellular function in the desired direction and hence evaluate thyroid function. Thus, the proposed TS‐microsphere‐integrated cell aggregates may yield new fundamental insights for advancing in vitro cell‐based research.
Imparting Outstanding Dispersibility to Nanoscaled 2D COFs for Constructing Organic Solvent Forward Osmosis Membranes
Authors: Chen Li , Zhou Cailong , Yang Tianyi , Zhou Wei , Chen Ying , Wang Linghao , Lu Chenyang , Dong Lichun 
Published: March 2023

AbstractIn the context of thin‐film nanocomposite membranes with interlayer (TFNi), nanoparticles are deposited uniformly onto the support prior to the formation of the polyamide (PA) layer. The successful implementation of this approach relies on the ability of nanoparticles to meet strict requirements regarding their sizes, dispersibility, and compatibility. Nevertheless, the synthesis of covalent organic frameworks (COFs) that are well‐dispersed, uniformly morphological, and exhibit improved affinity to the PA network, while preventing agglomeration, remains a significant challenge. In this work, a simple and efficient method is presented for the synthesis of well‐dispersed, uniformly morphological, and amine‐functionalized 2D imine‐linked COFs regardless of the ligand composition, group type, or framework pore size, by utilizing a polyethyleneimine (PEI) shielded covalent self‐assembly strategy. Subsequently, the as‐prepared COFs are incorporated into TFNi for the recycling of pharmaceutical synthetic organic solvents. After optimization, the membrane exhibits a high rejection rate and a favorable solvent flux, making it a reliable method for efficient organic recovery and the concentration of active pharmaceutical ingredient (API) from the mother liquor through an organic solvent forward osmosis (OSFO) process. Notably, this study represents the first investigation of the impact of COF nanoparticles in TFNi on OSFO performance.
Optimizing d‐Orbital Electronic Configuration via Metal–Metal Oxide Core–Shell Charge Donation for Boosting Reversible Oxygen Electrocatalysis
Authors: Wu Wei , chen Runzhe , Chen Suhao , Wang Zichen , Cheng Niancai 
Published: March 2023

AbstractTuning the d‐orbital electronic configuration of active sites to achieve well‐optimized adsorption strength of oxygen‐containing intermediates toward reversible oxygen electrocatalysis is desirable for efficient rechargeable Zn‐Air batteries but extremely challenging. Herein, this work proposes to construct a Co@Co3O4 core–shell structure to regulate the d‐orbital electronic configuration of Co3O4 for the enhanced bifunctional oxygen electrocatalysis. Theoretical calculations first evidence that electron donation from Co core to Co3O4 shell could downshift the d‐band center and simultaneously weak spin state of Co3O4, result in the well‐optimized adsorption strength of oxygen‐containing intermediates on Co3O4, thus contributing a favor way for oxygen reduction/evolution reaction (ORR/OER) bifunctional catalysis. As a proof‐of‐concept, the Co@Co3O4 embedded in Co, N co‐doped porous carbon derived from thickness controlled 2D metal‐organic‐framework is designed to realize the structure of computational prediction and further improve the performance. The optimized 15Co@Co3O4/PNC catalyst exhibits the superior bifunctional oxygen electrocatalytic activity with a small potential gap of 0.69 V and a peak power density of 158.5 mW cm−2 in ZABs. Moreover, DFT calculations shows that the more oxygen vacancies on Co3O4 contribute too strong adsorption of oxygen intermediates which limit the bifunctional electrocatalysis, while electron donation in the core–shell structure can alleviate the negative effect and maintain superior bifunctional overpotential.