bluuebunny/crossref_metadata_2025_split huggingface dataset:
BULGAR EDEBİYATINDAKİ İLK İSTANBUL SEYAHATNAMESİ ÜZERİNE BAZI GÖZLEMLER
Authors: MEVSİM Hüseyin 
Published: June 2023

Yüzyıllar boyunca İstanbul; Bulgar siyasi, askerî ve manevi tarihinde tayin edici rol oynamıştır. Günümüzde de her Bulgar, Boğaz kıyısındaki eşsiz şehri kendine çok yakın bulur. Ancak Bulgar edebiyatında İstanbul’u odağına alan ilk seyahatname, oldukça geç, 19. yüzyıl sonlarında kaleme alınır. Bu gecikmenin açıklanabilmesi için Bulgar’ın içindeki seyyahın, Bulgar toplumunun kaçınılmaz sancılar beraberinde modern hayata eklemlenmeye çabaladığı 1890’larda ortaya çıktığının göz önünde bulundurulması gerekir. Daha önceki yıllarda yazılan ve seyahatname türünün başlıca ögelerini barındıran eserlerde yerel coğrafyanın kapsandığı, Osmanlı İmparatorluğu sınırlarının dışına çıkılmadığı görülür.
Bu çalışmada payitahtın Bulgar tarihindeki yeri, ünlü şair ve gazeteci Petko Slaveykov’un İstanbul tasviri (1866) ve ilk doktoralı Bulgar hekim olan Dimitır Mollov’un bir dergide yayınladığı İstanbul izlenimleri (1888) hakkında kısaca bilgi verildikten sonra Bulgar edebiyatında ilk İstanbul seyahatnamesinin yazarı olan Todor Yankov’un hayat hikâyesi ve anılan eserle ilgili bazı gözlemler üzerinde durulmaktadır. Avrupalı bir seyyah yaklaşımı içinde şehrin sadece parıltılı yerlerini ve mekânlarını gezmekle yetinmeyen yazar, İstanbul’un eğri sokaklarına iner, caddelerde sokak köpekleri ve faytonlar arasında yürür, çarşılarda dolaşır, kahvehanede Türk kahvesi yudumlar, tekkede müridin tutkusuna ortak olur. Todor Yankov’un sıradan insana ve tekdüze akan hayatı canlandırmaya yönelik çabası, seyahatnameye ayrı değer katar ve özgünlük kazandırır. Kadim şehirde yalnızca Bulgar millî ve manevi tarihinin iz düşümleriyle ilgilenmemesi ise Avrupa değerlerini benimsemiş, farklı dünya görüşüne sahip bir kuşağı temsil etmesiyle açıklanabilir.
Microscopic Modelling of Car-Following Behaviour: Developments and Future Directions
Authors: He Yinglong , Zhou Quan , Wang Chongming , Li Ji , Shuai Bin , Lei Lei , Xu Hongming 
Published: June 2023

Review Microscopic Modelling of Car-Following Behaviour: Developments and Future Directions Yinglong He 1, * , Quan Zhou 2, * , Chongming Wang 3, Ji Li 2, Bin Shuai 2, Lei Lei 4, and Hongming Xu 2 1 School of Mechanical Engineering Sciences, University of Surrey, Guildford GU2 7XH, UK 2 Department of Mechanical Engineering, University of Birmingham, Birmingham B15 2TT, UK 3 Institutes for Future Transport and Cities, Coventry University, Coventry CV1 5FB, UK 4 College of Information Science and Engineering, Jiaxing University, Jiaxing 314001, China * Correspondence: yinglong.he@surrey.ac.uk (Y.H.); q.zhou@bham.ac.uk (Q.Z.) Received: 17 April 2023 Accepted: 21 June 2023 Published: 27 June 2023 Abstract: The study of driving behaviour has become increasingly important in the development of transport and vehicle technologies. Microscopic traffic models simulate individual driver behaviour to understand and predict traffic flow. One of the key components in microscopic simulation is the car-following (CF) model, which describes the behaviour of vehicles in terms of how they follow the vehicle in front of them. Some excellent reviews of CF models are available, however, to the best of the authors’ knowledge, none of them provides a comprehensive analysis that covers and compares different model categories including kinematics-based, dynamics-based, psychological-based, and learning-based. This paper, therefore, provides an overview of the developments and future directions of CF models, encompassing all the previously mentioned categories. It first introduces the fundamental concepts of traffic models, in particular CF models. It then reviews the progress of CF models, which are classified into the above four categories. The advantages and limitations of existing CF models are discussed. The paper further identifies several research directions for future work, including the integration of emerging vehicle technologies, the incorporation of real-world traffic data, and the calibration and validation of model parameters. It concludes by emphasizing the importance of interdisciplinary collaboration and the need for further research to improve the accuracy and practicality of CF models.
Reactive-Advective-Diffusive Models for the Growth of Gliomas Treated with Radiotherapy
Authors: Machado Bruno da Silva , Alvarez Gustavo Benitez , Cesar Lobão Diomar 
Published: June 2023

Gliomas are malignant brain tumors responsible for 50% of primary human brain cancer cases. They have a combination of rapid growth and invasiveness, and high fatality rates with a median survival time of one year. Mathematical models that describe its growth have helped to improve treatment. In this paper, a combined model formed by terms of two other models known in the literature is analyzed. The combined model is a Reactive-Advective-Diffusive partial differential equation, which is solved by combining the finite difference method, the Crank-Nicolson method and the upwind method. Logistic growth is used for cell proliferation ensuring a saturation threshold for glioma growth, which is crucial to properly estimate patient survival time. The well-known linear-quadratic radiobiological model is used to describe cell death due to radiotherapy treatment. Two initial conditions are compared in the simulations, indicating the need for further studies to have a model as close as possible to reality. Simulation results are shown for four scenarios: no radiotherapy, application of a single dose, and two dose fractionation schemes.
Conciseness and Persuasion in Academic Writings of Native and Non-native Writers: A Comparative Grammatical Metaphor Analysis
Authors: Qasim Hafiz Muhammad , Huma Huma Bukhari , Nawaz Muhammad Shafqat 
Published: June 2023

Academic writing is an integral part of academic success and international demands. It requires concise, persuasive, and contextual construction of sentences. This study aims to investigate the construction of concise, persuasive and generic patterns in twenty-five native and twenty-five Pakistani research articles’ abstracts. Using a mixed-method approach, fifty articles have been collected through a stratified random sampling technique. Five native journals (American Journal of Education, Applied Linguistics Journal, British Journal of Learning Disabilities, Journal of the Acoustical Society of America, and British Journal of Educational Studies) and five Pakistani journals (Pakistani Journal of Language and Translation, Al-Qualm, Humdard Islamic us, NUML Journal of Critical Inquiry, and Pakistan Journal of Social Sciences) are used for data collection. The instruments for analysis include percentages, qualitative analysis, Bitchener’s move model (2010), and AntConc. The study showed that the native and Pakistani writers equally used move structures, but differences occurred in the application of grammatical metaphor (GM) that was high in native writings. The study has provided insights into better and improved writing techniques that are required for concise and formal writing. These implications serve as a useful guide for English teachers and syllabus designers to include GM in course content for better writing skills.
LIBERDADE DE ENSINAR: CONDIÇÃO INDISPENSÁVEL À CONSTRUÇÃO DE UMA NOVA HEGEMONIA
Authors: Forti Lorena 
Published: June 2023

Este ensaio vale-se de reflexões gramscianas como fundamento na defesa da imprescindibilidade da liberdade de ensinar dos/as professores/as da Educação Básica no bojo do projeto de construção de uma nova hegemonia —alicerçada nos interesses do povo. Para isso, percorre o caminho argumentativo de mostrar: em primeiro lugar, a relevância da profissão docente na conformação das sociedades modernas; e, a partir daí, a visão de Gramsci tanto no que tange à importância estratégica da instituição escolar para a autodeterminação das classes subalternas quanto no que se refere ao “tipo” de intelectual que ela deve formar para que uma vontade coletiva de base popular se constitua.
Governance en compliance in de zorg na invoering van de Governancecode Zorg 2022 en de publicatie van het Kader Goed Bestuur 2022
Authors: Oostwouder W.J. , Monsma S. , Peelen A. 
Published: June 2023

Governance en compliance in de zorg na invoering van de Governancecode Zorg 2022 en de publicatie van het Kader Goed Bestuur 2022
Op 1 januari 2022 is de herziene Governancecode Zorg (hierna: de herziene Code) ingevoerd en in mei 2022 is het Kader Goed Bestuur 2022 van de Inspectie Gezondheidszorg en Jeugd (hierna: het nieuwe Kader Goed Bestuur) gepubliceerd. Voorts is in september 2022 het Integraal Zorgakkoord (hierna: IZA) gesloten met het doel om de zorg voor de toekomst goed, toegankelijk en betaalbaar te houden. Daarbij zijn afspraken gemaakt tussen het Ministerie van Volksgezondheid, Welzijn en Sport en een groot aantal partijen in de zorg. Ondertekenaars van het IZA zijn onder meer overkoepelende organisaties van ziekenhuizen, de geestelijke gezondheidszorg en de ouderenzorg. Deze afspraken strekken onder andere tot het bevorderen van samenwerking in de zorg. De auteurs pogen in dit artikel mede aan de hand van de herziene Code en het nieuwe Kader Goed Bestuur de volgende vragen te beantwoorden: (1) hoe kan binnen zorginstellingen een goede governance worden gewaarborgd; en (2) welke rol spelen compliance, strategie en risicomanagement daarbij? En naar aanleiding van het IZA: (3) wie is er verantwoordelijk voor de governance en compliance van een samenwerkingsverband in de zorg?
Pelaksanaan Discharge Planning Pada Pasien Diabetes Mellitus Tipe II Di Rumah Sakit Putri Hijau Medan
Authors: Kurzaini Muhammad Irfan , Syafrinanda Virginia , Olivia Nina 
Published: June 2023

Diabetes Mellitus merupakan suatu kelompok penyakit metabolik pada proses penguraian nutrisi dari makanan menjadi energi yang memiliki karakteristik hiperglikemia kronik yang terjadi karena kelaianan sekresi insulin, kerja insulin, atau kedua-duanya. Menurut International Diabetes Federation (IDF) memperkirakan terdapat 463 juta penderita pada usia 20-79 tahun di dunia tahun 2019 dan akan terus meningkat. Data Riskesdas 2018 menyatakan Kota Medan menempati peringkat ke-4 terbanyak di Sumatera utara. Metode Penelitian ini menggunakan metode deskriptif dengan rancangan studi kasus pemberian discharge planning dengan meliputi tahapan Pengkajian, Diagnosa Keperawatan, Intervensi, Implementasi, Evaluasi. Hasil penelitian diperoleh hasil yang sama antara kasus I dan kasus II pada hari ke - 3 setelah diberikan intervensi keperawatan tentang discharge planning masalah kurang pengetahuan sudah teratasi. Hasil yang didapatkan yaitu tingkat pengetahuan pasien I adalah 87,5% dan pasien II 95%. Kesimpulan pemberian discharge planning dapat mengatasi masalah kurang pengetahuan pada pasien. Saran peneliti menyarankan untuk melakukan discharge planning pada pasien diabetes melitus sebelum kepulangannya.
Effect of Finished Goods Inventory Accounting Information System on Finished Goods Inventory Intern Control at a Textile Company in the City Of Bandung
Authors: Yanuar Kiki , Suzanto Boy , Coenraad Dhea Perdana , Titi Titi , Jannah Annita 
Published: June 2023

The implementation of the research took place at one of the textile companies in the city of Bandung. The
research method used in this study is a quantitative research method with a descriptive method approach
and a verification method (correlation coefficient, simple regression, coefficient of determination). The
population in this study amounted to 30 people. The results showed that the Finished Goods Inventory
Accounting Information System was in the pretty good category with a score of 3.24, and the Internal
Control of Finished Goods Inventory was in the pretty good category with a score of 3.18. The results of
calculating the independent variable, namely the Finished Goods Inventory Accounting Information
System, At the same time, the dependent variable is the Finished Goods Inventory Internal Control.
Therefore, this study has a strong correlation because it shows the results of calculating the correlation
coefficient, which has a value of r = 0.862. Furthermore, simple linear regression that is Y = 1.909 + 0.890
X. Therefore, the coefficient of determination (R2) expressed as a percentage illustrates the magnitude of
the effect of the accounting information system on ready-to-use goods inventory (x) on Finished Goods
Inventory internal control (y) of 0.744 or 74.4%. The remaining 25 are the influence of other factors that
the authors did not examine in this study.
Tutoría entre iguales: una alternativa didáctica enfocada en mejorar el rendimiento académico en Matemáticas
Authors: Plaza Chalco José Luis 
Published: June 2023

Este artículo científico tiene como objetivo implementar una alternativa didáctica enfocada en la técnica de tutoría entre iguales para mejorar el rendimiento académico en Matemáticas en los estudiantes del décimo E de la Unidad Educativa Luis Cordero. Para el cumplimiento de este objetivo, se realiza un estudio cuasiexperimental con enfoque mixto donde se tiene un grupo control y otro experimental lo cual ayuda a medir el impacto de la técnica tutoría entre iguales en comparación de la metodología tradicional. Entre los instrumentos de recolección de datos empleados, destaca el uso de un pretest y postest que sirve para conocer el rendimiento académico inicial y final de la muestra estudiada. La implementación de la técnica antes descrita tiene 3 fases las cuales son: preparación, ejecución y evaluación. Los resultados indican que la técnica tutoría entre iguales es efectiva para mejorar habilidades sociales tales como la comunicación entre estudiantes y la responsabilidad tanto individual como colectiva. Además, tiene un efecto positivo en el rendimiento académico, dado que, el grupo experimental obtuvo mejores resultados en el postest, trabajos en clase y evaluaciones individuales.
KHẢO SÁT TÌNH TRẠNG TĂNG CANXI MÁU Ở NGƯỜI CAO TUỔI BỆNH UNG THƯ
Authors: Nguyễn Ngọc Hoành Mỹ Tiên , Trần Lý Mỹ Châu , Thân Hà Ngọc Thể 
Published: June 2023

Mục tiêu: Khảo sát tình trạng tăng canxi máu ở người cao tuổi bệnh ung thư tại khoa Điều trị giảm nhẹ, bệnh viện Chợ Rẫy.
Đối tượng và phương pháp: Nghiên cứu cắt ngang, mô tả, tiến cứu, tiến hành trên 46 người cao tuổi (≥ 60 tuổi) bệnh ung thư, tại khoa Điều trị giảm nhẹ, bệnh viện Chợ Rẫy từ ngày 11/2020 đến 06/2021, có tăng canxi máu hiệu chỉnh (> 2,6 mmol/L).
Kết quả: Tỷ lệ tăng canxi máu ở người cao tuổi bệnh ung thư chiếm 2%, với u phổi chiếm đa số 17,4%, di căn xương và gan chiếm 37%. Tỷ lệ nhiễm khuẩn lên đến 60,9%. Đa số đều có suy giảm chức năng thận, độ lọc cầu thận từ 15 - < 60 chiếm 34,8%, độ lọc cầu thận giảm nặng < 15, chiếm 58,7%. Diễn tiến nặng chiếm 45,7%, tử vong là 6,5%.
Kết luận: Tỷ lệ tăng canxi máu ở người cao tuổi bệnh ung thư là 2%, với đặc điểm lâm sàng rất đa dạng. Hầu hết đều suy thận nặng, diễn tiến nặng, tử vong là 6,5%.
A preliminary study of the salivary microbiota of young male subjects before, during, and after acute high-altitude exposure
Authors: Zhou Qian , Chen Yuhui , Liu Guozhu , Qiao Pengyan , Tang Chuhua 
Published: June 2023

Background
The microbial community structure in saliva differs at different altitudes. However, the impact of acute high-altitude exposure on the oral microbiota is unclear. This study explored the impact of acute high-altitude exposure on the salivary microbiome to establish a foundation for the future prevention of oral diseases. Methods. Unstimulated whole saliva samples were collected from 12 male subjects at the following three time points: one day before entering high altitude (an altitude of 350 m, pre-altitude group), seven days after arrival at high altitude (an altitude of 4,500 m, altitude group) and seven days after returning to low altitude (an altitude of 350 m, post-altitude group). Thus, a total of 36 saliva samples were obtained. 16S rRNA V3-V4 region amplicon sequencing was used to analyze the diversity and structure of the salivary microbial communities, and a network analysis was employed to investigate the relationships among salivary microorganisms. The function of these microorganisms was predicted with a Phylogenetic Investigation of Communities by Reconstruction of Unobserved States (PICRUSt) analysis.

Results
In total, there were 756 operational taxonomic units (OTUs) identified, with 541, 613, and 615 OTUs identified in the pre-altitude, altitude, and post-altitude groups, respectively. Acute high-altitude exposure decreased the diversity of the salivary microbiome. Prior to acute high-altitude exposure, the microbiome mainly consisted of Proteobacteria, Firmicutes, Bacteroidetes, Fusobacteria, and Actinobacteria. After altitude exposure, the relative abundance of Streptococcus and Veillonella increased, and the relative abundance of Prevotella, Porphyromonas, and Alloprevotella decreased. The relationship among the salivary microorganisms was also affected by acute high-altitude exposure. The relative abundance of carbohydrate metabolism gene functions was upregulated, while the relative abundance of coenzyme and vitamin metabolism gene functions was downregulated.

Conclusion
Rapid high-altitude exposure decreased the biodiversity of the salivary microbiome, changing the community structure, symbiotic relationships among species, and abundance of functional genes. This suggests that the stress of acute high-altitude exposure influenced the stability of the salivary microbiome.
Diferenças clínicas, radiológicas e espirométricas entre os pacientes pós-covid-19 estratificados de acordo com a gravidade inicial da doença
Authors: Mariano Paulo Mateus Madureira Soares , Sarno Filho Marcelo Vincenzo , Neves Rafael Costa Sarno , Jesus Fabíola Ramos , Albuquerque Marcel Lima , Barbosa Sória Ramos , Neves Margarida Célia Lima Costa 
Published: June 2023

Introdução: em março de 2020, a pandemia do SARS-CoV-2 foi declarada pela OMS, contabilizando mais de seis milhões de mortes e 600 milhões de casos confirmados. São necessários estudos para compreender a persistência dos sintomas após a infecção aguda, que podem se correlacionar com a gravidade inicial da doença. Objetivo: avaliar e comparar as características clínicas, espirométricas e radiológicas dos pacientes acometidos pela síndrome pós-COVID, estratificados conforme gravidade da infecção aguda pelo Sars-Cov-2. Metodologia: trata-se de estudo de corte transversal, realizado a partir de consultas ambulatoriais em amostra de conveniência. O estudo incluiu 232 pacientes, atendidos de novembro de 2020 a outubro de 2021. Os pacientes foram divididos em 2 grupos: com COVID-19, sem internamento em unidade de terapia intensiva; e com internamento em unidade de terapia intensiva. Resultados: foram avaliados 232 pacientes acometidos pela COVID-19, sendo 69,4% do sexo feminino; idade média de 50 ± 12,8 anos. As comorbidades mais frequentes foram hipertensão arterial sistêmica (44,0%) e diabetes mellitus (21,1%). Dos pacientes estudados, 45,7% foram internados durante a fase aguda da doença, sendo que cinquenta (21,6%) foram alocados em unidade de terapia intensiva (UTI). Em relação à espirometria, o padrão de distúrbio restritivo foi verificado apenas nos pacientes internados em UTI. Na tomografia de tórax, o padrão de pneumonia em organização foi associado a pacientes que precisaram de internamento em unidade de terapia intensiva. Conclusão: este estudo evidencia que o distúrbio ventilatório restritivo e a presença de pneumonia em organização tiveram associação com quadros iniciais mais graves.
The Design of Metal Complexes to Target the Amyloid‐β Peptide in Alzheimer's Disease
Authors: Webb Michael I. 
Published: June 2023

Abstract
Alzheimer's disease (AD) is a devastating neurological disorder where a pathological hallmark is the occurrence of amyloid‐β (Aβ) peptide deposits, also known as Aβ plaques. The Aβ peptide is known to self‐associate and aggregate in solution, a phenomenon that is accelerated in the presence of metal ions, in particular Fe, Cu, and Zn. Furthermore, these micronutrient metals are found in elevated concentration within Aβ plaques, relative to nearby healthy tissues. Therapeutic approaches have sought to exploit this metalloprotein nature of Aβ by designing metal complexes that can target either the soluble peptide or its pathological aggregate species. Overall, complexes of 27 different metals have been designed to target the Aβ that can detect its presence in biological samples, modulate its aggregation, and/or prevent its neurotoxic activity. This article summarizes these compounds, and the advances made for complexes of each metal.
Iron–Sulfur Clusters in Viral Diseases
Authors: Raza Md Kausar , Karges Johannes 
Published: June 2023

Abstract
Iron–sulfur [Fe–S] clusters are among the oldest cofactors known on earth. These compounds are structurally and functionally highly versatile and therefore used in various biological processes including biochemical catalysis, electron transfer reactions, sulfur donation, as well as sensing. To date, the presence of functioning [Fe–S] clusters has been verified in all types of living organisms including bacteria, archaea, and eukaryotes. Studies have shown that the biological activity of the [Fe–S] cluster is mainly attributed to its highly accessible and reversible redox activity, which can range over several oxidation and spin states. Over the last years, [Fe–S] clusters have been identified as a key component in various viral diseases including but not limited to polyomaviruses, rotaviruses, hepatitis b virus, and coronaviruses. Within this article, the potential role of [Fe–S] clusters in viral diseases is critically reviewed.
Finetuning the Coordination Chemistry of Nontoxic Titanium(IV) for Cancer Therapy and Diagnosis
Authors: Acosta‐Mercado Jemily , Vargas‐Figueroa Adriana I. , García‐Alfonzo Miguel E. , Del Valle‐González Yolmarie L. , Figueroa‐Robles Adrián , Torres‐Martinez Amarilis , Gonzalez‐Dumeng Christian M. , Almánzar Rodríguez Emily J. , Díaz‐Rivera Josean , Boyne‐Mascarell Juan C. , Soto‐Ramos Stephanie A. , Ortiz Colón Yermarie W. , Tinoco Arthur D. 
Published: June 2023

AbstractDeveloping effective strategies to address current cancer treatment and diagnosis challenges is imperative. Research has led to many medical breakthroughs, namely in the use of small molecules for chemotherapy as a major component of the standard of patient care. Following the serendipitous finding of cisplatin as an anticancer agent in the 1960s, titanium(IV) emerged as a metal of medicinal interest given its general nontoxicity. Many researchers have championed the potential clinical use of Ti(IV) compounds as anticancer agents given how manipulation of its coordination chemistry with the judicious selection of ligands leads to impressive cytotoxic properties with different mechanisms of action. By studying the biological speciation of the Ti(IV) compounds and their mechanism of action within cells and in vivo, much insight has been gained about the limitations posed to their therapeutic potential and about how the ligands can be finetuned to play a more active role to increase potency and specificity for cancer cells. In this review, we will take a historical tour of the evolution of titanium(IV) in its application in cancer research, dissecting the chemical properties of the metal ion that confer it with great potential for utility in different areas of cancer treatment and diagnosis. We explore the rich coordination chemistry of Ti(IV) that has led to different library of anticancer compounds and also survey efforts to use visible to activate TiO2nanoparticles as photosensitizers. In the latter part of the manuscript, we revisit the coordination chemistry of Ti(IV) as it illuminates ligand types that may facilitate the use of45Ti for PET imaging and possibly even theranostics. This work elucidates optimal approaches to bringing Ti(IV) to the anticancer market.