bluuebunny/crossref_metadata_2025_split huggingface dataset:
Migration motivation and ethnic identity of migrant couples: tied versus lead movers*
Authors: Monteiro Teresa Freitas 
Published: April 2023

Abstract
This study examines the determinants of the migration status within households (tied or lead mover) and how it affects the ethnic identity of migrant spouses. Tied and lead movers differ in their migration motivations, face different constraints, and opportunities (e.g., social network through work). This is likely to be reflected in different investment strategies and adjustment patterns in the host country. To study the adjustment of tied and lead movers, I rely on the IAB-SOEP migration sample, which asks migrant spouses who were the main driver of the migration decision and measures several socio-economic outcomes in Germany. The results show that women are 42.2 percentage points more likely to be tied movers than men, and spouses without technical college or university before migration is 6.6 percentage points more likely to be tied movers than spouses with a degree. Overall, tied movers in Germany are more likely to be separated and less likely to be integrated and assimilated when compared to lead or equal movers. These findings suggest that for tied movers, the benefits of investing in the host country's culture do not outweigh the costs.
Playing HAVOK on the Chaos Caused by Internet Trolls
Authors: Martynova Elena , Golino Hudson , Boker Steven M. 
Published: April 2023

Abstract
Trump supporting Twitter posting activity from right-wing Russian trolls active during the 2016 United States presidential election was analyzed at multiple timescales using a recently developed procedure for separating linear and nonlinear components of time series. Trump supporting topics were extracted with DynEGA (Dynamic Exploratory Graph Analysis) and analyzed with Hankel Alternative View of Koopman (HAVOK) procedure. HAVOK is an exploratory and predictive technique that extracts a linear model for the time series and a corresponding nonlinear time series that is used as a forcing term for the linear model. Together, this forced linear model can produce surprisingly accurate reconstructions of nonlinear and chaotic dynamics. Using the R package havok, Russian troll data yielded well-fitting models at several timescales, not producing well-fitting models at others, suggesting that only a few timescales were important for representing the dynamics of the troll factory. We identified system features that were timescale-universal versus timescale-specific. Timescale-universal features included cycles inherent to troll factory governance, which identified their work-day and work-week organization, later confirmed from published insider interviews. Cycles were captured by eigen-vector basis components resembling Fourier modes, rather than Legendre polynomials typical for HAVOK. This may be interpreted as the troll factory having intrinsic dynamics that are highly coupled to nearly stationary cycles. Forcing terms were timescale-specific. They represented external events that precipitated major changes in the time series and aligned with major events during the political campaign. HAVOK models specified interactions between the discovered components allowing to reverse-engineer the operation of Russian troll factory. Steps and decision points in the HAVOK analysis are presented and the results are described in detail.
The solutions of the quaternion multiple equality constrained least squares problem
Authors: Zhang Fengxia , Li Ying 
Published: April 2023

Abstract
Many data models of practical problems are related to the quaternion multiple equality constrained least squares (QMELS) problem, which is a generalization of the quaternion equality constrained least squares (QELS) problem. In this paper, by utilizing the MP inverse, the quaternion QR factorization, the quaternion CS factorization and some known results of the QELS problem, we first transform the QMELS problem into an unconstrained least squares (LS) problem. Next, we give a representation formula for solutions of the QMELS problem. After that, we present a real structure-preserving algorithm of its minimum norm solution. Finally, a example is proposed to indicate the validity.
Generative model for learning quantum ensemble with optimal transport loss
Authors: Tezuka Hiroyuki , Uno Shumpei , Yamamoto Naoki 
Published: April 2023

Abstract
Generative modeling is an unsupervised machine learning framework, that exhibits
strong performance in various machine learning tasks.
Recently we find several quantum version of generative model, some of which
are even proven to have quantum advantage.
However, those methods are not directly applicable to construct a generative
model for learning a set of quantum states, i.e., ensemble.
In this paper, we propose a quantum generative model that can learn quantum
ensemble, in an unsupervised machine learning framework.
The key idea is to introduce a new loss function calculated based on optimal
transport loss, which have been widely used in classical machine learning
due to its good properties; e.g., no need to ensure the common support of two
ensembles.
We then give in-depth analysis on this measure, such as the scaling property
of the approximation error.
We also demonstrate the generative modeling with the application to quantum
anomaly detection problem, that cannot be handled via existing methods.
The proposed model paves the way for a wide application such as the health
check of quantum devices and efficient initialization of quantum computation.
On the detection of lateral movement through supervised machine learning and an open-source tool to create turnkey datasets from Sysmon logs
Authors: Smiliotopoulos Christos , Kambourakis Georgios , Barbatsalou Konstantia 
Published: April 2023

Abstract
Lateral movement (LM) is a principal, increasingly common, tactic in the arsenal of advanced persistent threat (APT) groups and other less or more powerful threat actors. It concerns techniques that enable a cyberattacker, after establishing foothold, to maintain ongoing access and penetrate further into a network in quest of prized booty. This is done by moving through the infiltrated network and gaining elevated privileges using an assortment of tools. Concentrating on the MS Windows platform, this work provides the first to our knowledge holistic methodology supported by an abundance of experimental results towards the identification of LM via machine learning (ML) techniques. We not only assess this potential by means of both traditional and deep learning models, but also contribute a publicly available, open-source tool, which can convert Windows system monitor logs to turnkey datasets, ready to be fed into ML models. Vis-`a-vis the relevant literature, and by considering a highly unblalanced dataset and a multiclass classification problem, we report superior scores in terms of the F1 and AUC metrics, 99.41% and 99.84%, respectively.
Evaluation of Immunophenotypic Alterations of Peripheral Blood Lymphocytes and their Sub-Sets in Uncomplicated P. Falciparum Infection
Authors: Antwi-Baffour Samuel , Mensah Benjamin Tetteh , Ahiakonu Simon Aglona , Armah Dorinda Naa Okailey , Ali-Mustapha Samira , Annison Lawrence 
Published: April 2023

Abstract
Background: Malaria is a life-threatening parasitic disease typically transmitted through the bite of an infected Anopheles mosquito. There is ample evidence showing the potential of malaria infection to affect the counts of lymphocyte subpopulations in the peripheral blood, but the extent of alteration might not be consistent in all geographical locations, due to several local factors. Although Ghana is among the malaria endemic countries, there is currently no available data on the level of alterations that occur in the counts of lymphocyte subpopulations during Plasmodium falciparum malaria infection among adults.
Aim: The study was to determine the immunophenotypic alterations in the level of peripheral blood lymphocytes and their subsets in adults with uncomplicated P. falciparum malaria infection and apparently healthy participants.
Methods: The study was a cross-sectional comparative study conducted in two municipalities of the Volta region of Ghana. Blood samples were collected from study participants and taken through serology (P. falciparum/Pan Rapid Diagnostic Kits), microscopy (Thick and thin blood films) and Haematological (Flow cytometric and Full blood count) analysis.
Results: A total of 414 participants, comprising 214 patients with malaria (cases) and 200 apparently healthy individuals (controls) were recruited into this study. Parasite density of the malaria patients ranged from 75/µL to 84,364/µL, with a mean of 3,520/µL. It was also observed that the total lymphocytes slightly decreased in the P. falciparum infected individuals (Mean ± SD: 2.08 ± 4.93 × 109/L) compared to the control group (Mean ± SD: 2.47 ± 0.80 × 109/L). Again, there was a significant medium positive correlation between parasite density and haematocrit levels (r= 0.321, p < 0.001). Apart from CD45+ T-cells, more people in the control group had normal values for the lymphocyte subsets measured compared to the cases.
Conclusions: From the results obtained, there was high parasite density among the malaria patients suggestive of high intensity of infection in the case group. The cases again showed considerable haematological alterations in lymphocyte sub-sets and the parasite density appeared to be strongly associated with CD4+ T-cell reduction. Also, the parasite density significantly associated with decreasing haematocrit levels.
Comparative Evaluation of Vehicle, Dose, and Duration-related Oxidative, Cardiotoxic, Inflammatory and Histologic Responses of Chromium 6+ and Doxorubicin in Rats’ Heart
Authors: Onyedikachi Uchechi Bliss , Egbuonu Anthony Cemaluk Chinedum , Awah Favour Matthew , Ijioma Solomon Nnah , Nkpaa Kpobari W. 
Published: April 2023

Abstract
Doxorubicin (Dox) is cardiotoxicity is established while chromium 6+ compound (Cr[VI]) could be cardiotoxic due to its bioaccumulation capacity. This study compared vehicle, dose, and duration-related oxidative, cardiotoxic, inflammatory and histologic responses of Cr[VI] and Dox intoxication in rats’ heart by standard protocols. The rats were respectively intoxicated with Cr [VI] and Dox in 3 different phases. In the first phase, sixty rats were assigned to six groups of ten each. Group 1 served as the Control while groups 2, 3, and 4 were treated with oral doses of 10, 20, and 30 mg/kg body weight (b.wt) of K2Cr2O7 (Cr[VI]) solution while groups 5 and 6 received intraperitoneal administration of 15 and 20 mg/kg b.wt Dox for two days, respectively, before the sacrifice. The procedure was repeated in the second and third Phases, but for 60 days. Oxidative, cardiotoxic, inflammatory and histologic indices were determined in the rats’ heart. The results indicated that exposure to either Dox or Cr{VI] caused a significant (P < 0.05) dose, vehicle and duration-dependent decrease in Superoxide dismutase (SOD), Glutathione peroxidase (GPx), Catalase (CAT) activities and Nitric Oxide(NO) levels but an increase in Cardiac Troponin (CTnI) levels, Creatinine-kinase (CK-MB), C-reactive protein(CRP), Aspartate-transaminase(AST), Lactate-dehydrogenase (LDH) and Malondialdehyde (MDA) compared to the control. Heart histopathology of Dox- and Cr[VI] treated rats showed dose, vehicle and duration-dependent pulmonary oedema, hyaline necrosis and displacement of adjacent myocytes compared to control. Thus, Cr[VI] compared well with Dox in cardiotoxicity induction accompanied with oxidative stress, inflammatory and histo-hepatic responses in the rats’ heart.
Testing a subset of random effects in linear mixed models A comparative study
Authors: Abdelwahab Nada Mostafa , El-Horbaty Yahia S. , Ibrahim Ibrahim Hassan 
Published: April 2023

Abstract
In linear mixed-effects models, random effects are necessary, especially if the data has two sources of variation. As a result of the importance of random effects, various studies focused on testing the need for random effects. This topic is challenging, and several studies have been proposed for testing a subset of random effects using various approaches to tackling challenges with this problem. Existing tests involve the exact F-test, and other resampling-based tests. In this article, we conduct simulation studies to examine the size and the power of many of the recent tests for a subset of variance components in linear mixed-effects models. The study highlights the tests with the highest empirical power under some commonly used configurations.
CÓMO UTILIZAR LA ENFERMERÍA BASADA EN LA EVIDENCIA.
Authors: Caballero Muñoz Erika , Hernández Cortina Abdul 
Published: April 2023

La Enfermería basada en la evidencia se ha incorporado con fuerza en el mundo sanitario, su aplicación se basa en la necesidad de dar un cuidado de enfermería más seguro y de alta calidad, desafío que se hace necesario en esta sociedad del conocimiento, donde las enfermeras y enfermeros deben poseer competencias de búsqueda, organización, interpretación, evaluación critica y validación de información, aplicación de la evidencia en la práctica y evaluación de la efectividad, eficacia en latoma de decisiones con juicio clínico crítico. Así como competencias para la propia gestión del conocimiento y aprendizaje continuo. El presente artículo conceptualiza la enfermería basada en la evidencia y sus elementos, las limitaciones y la forma de enfrentarlas. Se analizan los pasos metodológicos desde la formulación de la pregunta clínica hasta la evaluación de la implementación de la evidencia.
Caracterización físico-química y microbiológica del agua de un municipio del departamento de Boyacá, Colombia
Authors: Dorado-González Liliana , Dueñas-Celis Mery , Suescún-Carrero Sandra Helena 
Published: April 2023

Introducción. El agua salubre y fácilmente accesible es importante para la salud pública, si se utiliza para beber, uso doméstico, producir alimentos o fines recreativos. El agua contaminada y el saneamiento deficiente están relacionados con la transmisión de enfermedades.
Objetivo. Evaluar las características físico químicas y microbiológicas de la red de distribución del acueducto urbano de un municipio de Boyacá.
Materiales y métodos. Estudio cuantitativo descriptivo transversal, se realizó la toma de muestras de agua en 13 puntos, siete concertados y materializados de la red de distribución, uno en la bocatoma de entrada de la planta, dos pozos y en tres nacimientos, de donde se abastece la población. Se realizaron análisis físicos, químicos y microbiológicos de cada una de las muestras.
Resultados. Las muestras sin tratamiento presentaron niveles altos de unidades platino cobalto y turbiedad. El cloro residual libre en dos muestras de agua tratada estaba por debajo de los límites establecidos. Se detectaron microorganismos heterótrofos y Coliformes en las muestras de agua obtenidas de fuentes de abastecimiento. En dos puntos se encontró quistes de Giardia y ooquistes de Cryptosporidium. De las 13 muestras estudiadas, tres arrojaron un Índice de Riesgo por calidad del agua inviable sanitariamente.
Conclusiones. Se evidencia que el agua se encuentra en un nivel de riesgo inviable sanitariamente, lo cual demuestra que el sistema de tratamiento no es suficiente para garantizar el suministro de agua apta para el consumo humano.
Synthesis of Pneumatic Systems in the Control of the Transport Line of Rolling Elements
Authors: Szcześniak Adam , Szcześniak Zbigniew , Cedro Leszek 
Published: April 2023

Abstract
This paper presents the synthesis of a pneumatic control system for a selected configuration of the transport path for the delivery of rolling elements to spiral storage in inter-operational transport. The sequential control system sets the state of the manifolds to ensure a flow of workpieces to serve the subsequent storage. The essential module of the control system is the memory block. It is developed based on a storage filling sequence graph. The filling level of the storages can be monitored in one or two points using sensors. The rolling element displacement control sensors work together with appropriately designed systems to execute the delay of the rising and falling edge input signal. By using a two-level control of the filling level of the storages, it is possible to control the emptying status of the storages as a function of the technological time of removal of the items from the storage between the two control points. Control systems were synthesised and verified using Festo’s FluidSim computer programme.
PEG-liposomal doxorubicin as a potential agent for canine metastatic osteosarcoma – in vitro and ex ovo studies
Authors: Walewska Magdalena , Małek Anna , Taciak Bartosz , Wojtalewicz Anna , Wilk Sylwia , Wojtkowska Agata , Zabielska-Koczywąs Katarzyna , Lechowski Roman 
Published: April 2023

Abstract

Introduction
Appendicular osteosarcoma (OSA) is a highly aggressive and metastatic primary bone tumour in dogs. Standard therapy is amputation and adjuvant chemotherapy (e.g. with doxorubicin). Liposomal drug delivery may augment therapeutic efficacy and reduce negative side effects. Polyethylene glycol (PEG)-liposomal doxorubicin treats human metastatic cancers effectively. The study aimed was to evaluate PEG-liposomal doxorubicin’s inhibitory effect on canine metastatic proliferation and migration in vitro. It also aimed to appraise the drug’s extravasation inhibition in vivo using the human medicine–proven chick embryo chorioallantoic membrane ex ovo model.

Material and Methods
The canine D-17 OSA cell line was cultured and inoculated with decreasing concentrations of PEG-liposomal doxorubicin and conventional doxorubicin in a 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) test of cell viability, proliferation and cytotoxicity. Flow cytometry with Annexin V and Draq 7 staining confirmed the MTT test results, indicating dead, early and late apoptotic, and live cells. The inhibitory effect of the two preparations on cancer cell migration was investigated with a wound-healing assay. Culture plates seeded with cells were prepared. The cell monolayer was scratched and images of cells migrating to the scratch were captured at 0 h, 12 h and 24 h. Also, embryos were removed from three-day-incubated fertilised chicken eggs. On the 12th day, labelled D-17 cells were injected into each embryo. Embryos in one group received 100 μL of phosphate-buffered saline as controls, those in another group 30 μg/mL of PEG-liposomal doxorubicin, and those in the last group 6 μg/mL of conventional doxorubicin. The effectiveness of the intravascular administration of the D-17 cells was confirmed under a microscope.

Results
PEG-liposomal doxorubicin inhibited the migration of canine OSA cells more effectively than conventional doxorubicin (P ≤ 0.05). The ex ovo model showed that both drugs had similar impacts on canine metastatic OSA.

Conclusion
The liposomal form of the drug may be considered a potentially effective compound in canine metastatic OSA; nevertheless, further in vivo studies are essential to confirm this hypothesis.
Fe en Colombia. Un programa de todos y para todos
Authors: Valencia Valencia Mario Augusto 
Published: April 2023

El artículo presenta un acercamiento general al programa interinstitucional Fe en Colombia, expresando de manera particular los procesos articuladores que enfocan la integración público privada en un ámbito nacional e internacional, con la participación activa y eminentemente social de las Fuerzas Militares.
El propósito es mostrar, a través de los últimos cincuenta años, la evolución del concepto de Acción Integral, la doctrina y las capacidades instaladas para acompañar la institucionalidad en beneficio de las poblaciones vulnerables. Se hace a través de un análisis histórico de las experiencias y lecciones aprendidas de la relación civil-militar que han facilitado los cambios en las Fuerzas para un mayor acercamiento a la población, y una mejor combinación de seguridad y desarrollo social en las regiones más apartadas. El resultado se da mediante la creación de nuevos espacios de convivencia y construcción de confianza; integrando en toda la geografía nacional, la Fuerza Pública, instituciones del gobierno, organizaciones no gubernamentales y entidades del orden privado.
En conclusión, el programa Fe en Colombia, con una acción conjunta, coordinada e interagencial lleva la presencia estatal a las regiones, planteando líneas estratégicas de desarrollo en infraestructura, vías, bienestar y educación, aumentando la credibilidad de la institucionalidad frente a la población civil.
Science Competence Assessment at Middle School: Teacher's Perception and Practice
Authors: Vy Nguyen Thi Phuong , Lien Vu Phuong , Hung Le Thai 
Published: April 2023

Science competence is one of the most vital learning outcomes of Natural Science subjects in general education. The research presents a guideline to develop assessment criteria/toolkits following the science competence components containing science awareness, science inquiry, and scientific problem-solving. A topic titled "how to classify mixtures and separate the mixture" in natural science six is presented to illustrate the guideline. A deep interview method was applied with thirteen natural science teachers to gather information about teachers' perceptions and practices in teaching and assessing activities to support students in enhancing their science competence. Feedback from teachers about the proposed guidelines was also collected. The research results created a picture of implementing Natural Science subjects in secondary schools with information about the challenges and needs of teachers to improve the issues. This paper is expected to provide teachers have more valuable tools in the innovation phase toward competence-based teaching and assessment.
Hiperplasia Adrenal Congênita
Authors: Nunes Neto Sérgio Tavares , Bhering Carlos Alberto , Ouriques Nardo da Silva 
Published: April 2023

Objetivo: Analisar as características da Hiperplasia Adrenal Congênita (HAC). Revisão bibliográfica: A HAC compreende um grupo de doenças autossômicas recessivas causadas por mutações em um dos genes que codificam enzimas envolvidas na esteroidogênese adrenal. Pode resultar da falha de qualquer uma das enzimas envolvidas na cascata de síntese de hormônios esteróides e a forma mais comum é causada pela deficiência do esteroide 21-hidroxilase (21-OHD), afetando cerca de 1:15.000 nascidos vivos. A discriminação da HAC em formas Clássicas e Não Clássicas é baseada no grau de deficiência da 21-hidroxilase, sendo a HAC clássica subdividida em uma forma perdedora de sal e em uma forma virilizante. Considerações finais: A HAC é uma doença genética que possui duas formas principais de apresentação. A HAC clássica, mais grave e potencialmente fatal, pode ser diagnosticada através do teste do pezinho no Brasil, o que pode prevenir crises perdedoras de sal que representam o pior prognóstico da doença. A HAC não clássica é geralmente diagnosticada na puberdade ou adolescência. O manejo desta condição é feito através dos glicocorticóides, tendo em vista todas complicações da administração desse medicamento.
TASAVVUF EDEBİYATINDAKİ İNSAN-I KÂMİL İLE NİETZSCHE NİHİLİZMİNDEKİ ÜSTİNSAN
Authors: ÇAPIN Sema 
Published: April 2023

İdeal insan kimdir, nasıldır sorusu Antik Çağdan günümüze pek çok filozofun zihnini meşgul eden bir sorudur. Her medeniyetin algılayış ve tutumuna, beslendiği kaynağa, değişen zamana göre bu tanımlar değişse de söz konusu arayışın kendisi genelde ortak bir paydada buluşmaktadır. Bu ideal insan arayışı insanlık tarihi boyunca süregidecek olan bir arayış gibi de görünmektedir. Sıradan bir canlı, insanın ve insanlığın özünü, asıl mahiyetini tam olarak yansıtamaz. O halde ideal insan öyle olmalı ki tüm insanlıkta görünür hale gelmesi arzulansın.
Tasavvuf felsefesinde ve edebiyatındaki insan-ı kâmil ile Nietzsche nihilizmindeki üstinsan bu anlayışlarca arzulanan ideal insan tipleridir. Bu çalışmada amaç insan-ı kâmil ile üstinsanın benzer ve farklı yanlarını ortaya koymak, bu kavramlara daha objektif ve geniş bir perspektiften bakmayı sağlamaktır.