bluuebunny/crossref_metadata_2025_split huggingface dataset:
Correlation between Sonoelastographic, Doppler and Histopathological Findings in Chronic Kidney Disease Patients in Tertiary Care Centre
Authors: Jha S. K. , Lohani B. , Pant A. D. , Chataut D. , Regmi D. , Bhatta U. , Gautam N. , Jha G. 
Published: April 2023

Background Ultrasound (USG) with Doppler examination of intrarenal vessels is the imaging modality of choice employed in patients with renal failure and is commonly performed early in the clinical course. The pulsatility index (PI) and the resistive index (RI) of downstream renal artery have been found to correlate with renal vascular resistance, filtration fraction and effective renal plasma flow in chronic renal failure. Pathological process in any tissues alters their elastic properties which can be assessed non-invasively through newer technique like elastography.
Objective To correlate the findings obtained by sonoelastographic, doppler and histopathological studies in chronic kidney disease patients.
Method Study was done in 146 patients referred to Department of Radiodiagnosis and Imaging, TUTH for native renal biopsy. Renal sonographic morphology (length, echogenicity, cortical thickness), Sonoelastography (Young’s modulus) and Doppler parameters (peak systolic velocity, resistive index) were assessed. The grading of estimated GFR (eGFR) was calculated based on chronic kidney disease (CKD) criteria.
Result Among 146 patients, 63 (43.2%) were females and 83 (56.8%) were males. Maximum patients were in age group of 41-50 years (25.3%) followed by age group 51-60 years (24%). Mean age of patient was 42.06±14.70 for males and 39.57±12.54 females. Maximum mean Young’s modulus was seen in eGFR stage G1 with 46.57±19.51 kPa followed by in stage G3a with 36.46±10.01 kPa and observed to be statistically non-significant (p=0.172). However, statistical significance difference was noted between the resistive index and elastographic measurement of Young’s modulus (r=0.462, p=0.0001). Minimum mean cortical thickness was seen in eGFR stage G5 with 4.42±1.48 mm followed by stage G4 with 5.57±1.24 mm (p= 0.0001). Cortical thickness is decreasing as eGFR stage was increasing in our study (p=0.0001). Resistive index is increasing with decrease in renal size (r=-0.202, p=0.015).
Conclusion Ultrasonography along with doppler study and elastography have limited role in diagnosing the pathology of chronic kidney disease, however, it has significant role in the disease progression.
A Point Prevalence Study of the Use of Antibiotics in Six Tertiary Care Hospitals in the Kathmandu Valley, Nepal
Authors: Jha N. , Thapa B. , Pathak S. B. , Pandey A. , Pokhrel S. , Shankar P. R. , Bhandary S. , Mudvari A. , Dangal G. 
Published: April 2023

Background Point prevalence survey (PPS) on antibiotic use developed by the WHO has already been used in many hospitals globally.
Objective To obtain information on antibiotic prescription using point prevalence survey methodology in six private hospitals in the Kathmandu valley.
Method This descriptive cross-sectional study was completed during 20th July to 28th July 2021 using point prevalence survey methodology. The study was conducted among inpatients admitted at or before 8:00 AM on the day of survey in various wards. Data was presented as frequencies and percentages.
Result Maximum number of patients were above 60 years [34 (18.7%)]. Number of male and female participants were equal [91 (50%)]. Only one antibiotic was used in 81 patients (44.5%) followed by two antibiotics in 71 (39%) patients. Duration of prophylactic antibiotic use was one day in 66 (63.7%) patients. Blood, urine, sputum, and wound swabs were the common samples for culture. Cultures were positive for 17 (24.7%) samples. The common organisms isolated were E. Coli, Pseudomonas aeruginosa and Klebsiella pneumoniae. Ceftriaxone was the most used antibiotic. Drug and therapeutics, infection control committee and pharmacovigilance activities were present in 3/6 (50%) study sites. Antimicrobial stewardship was present in 3/6 (50%) and microbiological services was present in all hospitals. Antibiotic formulary and antibiotic guideline were present in 4/6 sites and facilities to audit or review surgical antibiotic prophylaxis choice in 2/6 (33.3%) sites, facility to monitor antibiotic use in 4/6 (66.6%) and cumulative antibiotic susceptibility reports in 2/6 (33.3%) study sites.
Conclusion Ceftriaxone was the most used antibiotic. E. Coli, Pseudomonas aeruginosa and Klebsiella pneumonia were the commonly isolated organisms. Not all parameters for infrastructure, policy and practice and monitoring and feedback were present at the study sites.
Rickettsial Infection amongst Febrile Illness Patient in a Tertiary Care Hospital: A Retrospective Cross-sectional Study
Authors: Gurung R. B. , Gurung R. B. , Sapkota P. , Bhatt S. , Tamang A. , Joshi S. , Khadka S. , Jaisy D. N. , Chalise S. , Shrestha P. 
Published: April 2023

Background Rickettsial infection is an emerging neglected tropical disease in the Southeast Asia. In past few years Nepal is also reporting escalating prevalence of rickettsia. The under evaluation is resulting it as undiagnosed or are simply labeled as pyrexia of unknown origin.
Objective To find out the prevalence of rickettsia in a hospital setting, assess the sociodemographic and other relevant clinical features of the rickettsia patients.
Method This is a hospital based retrospective cross-sectional study from October 2020 to October 2021. This study reviewed the medical records of the department.
Result The study included 105 eligible patients and the prevalence rate was 4.38 per 100 patients. The mean age of the participants was 42 years, and the mean hospital stay was 3 (SD ±2.06) days. More than 55% of the participants had fever for less than or equal to 5 days and 9% had Eschar present. Vomiting, headache, and myalgia were the most common symptoms and hypertension, and diabetes were the common comorbidities. Pneumonia and the acute kidney injury were the two complications of the patients as stated in the study. The severity of the thrombocytopenia deducted from admission time to discharge, and the case fatality was 4%.
Conclusion The future studies shall consider on collaborative clinical and entomological research. This would help in better understanding of the etiology of supposedly unknown febrile illness and the under-investigated field of emerging rickettsia in Nepal.
Évaluation du suivi des recommandations françaises sur la prise en charge des dermohypodermites bactériennes non nécrosantes au CHU de Poitiers : enquête sur l’évolution des pratiques en trois ans
Authors: Bessière L. , Boutin D. , Barbarin C. , Roblot F. Cazenave , Mimoz O. , Hainaut E. , Regnault M. Masson 
Published: April 2023

Objectifs : La Haute Autorité de santé a publié en 2019 des recommandations concernant la prise en charge des dermohypodermites bactériennes non nécrosantes (DHBNN). L’objectif de cette étude était d’évaluer le suivi de ces recommandations au centre hospitalo-universitaire de Poitiers sur les trois années suivant leur publication.
Matériel et méthodes : Étude rétrospective monocentrique sur dossiers de patients admis aux urgences pour prise en charge d’une DHBNN entre avril 2019 et avril 2022.
Résultats : Cent cinquante patients ont été inclus (50 patients par année). Il s’agissait de 87 femmes et 63 hommes d’un âge moyen de 77 ans. Le choix de l’antibiotique était jugé adéquat chez 130 patients (87 %) sans différence significative selon les périodes analysées. La posologie d’amoxicilline était adéquate chez 62 patients (59 %) toutes périodes confondues et dans 49, 62 et 68 % des cas sur les années n + 1, n + 2, n + 3, respectivement (NS). La durée de l’antibiothérapie était de 7 ± 2 jours et conforme aux recommandations dans 67 % des cas toutes périodes confondues. Elle était adéquate dans 56, 69 et 77 % des cas sur les années n + 1, n + 2, n + 3, respectivement. Une différence de pratique statistiquement significative était notée entre la période n + 1 et n + 3 (p = 0,03). Une porte d’entrée cutanée était retrouvée et traitée chez la plupart des patients (80 %). Les mesures associées (surélévation du membre, mise en place de contention veineuse, vaccination antitétanique, conseils diététiques) étaient peu proposées.
Conclusion : Cette étude met en évidence une adhésion croissante aux recommandations qui reste encore modeste concernant la posologie (trop faible) et la durée de l’antibiothérapie (trop prolongée). Il semble également nécessaire de rappeler l’importance des mesures associées et de prévention des récidives. La mise en place d’outils spécifiques (feuilles préremplies, fiche d’informations patient) pourrait favoriser leur application.
Construct-to-construct biplanar cantilever technique for spinal deformity correction: illustrative case
Authors: Sarmiento J. Manuel , Fourman Mitchell S. , Kim Han Jo 
Published: April 2023

BACKGROUND
There is a continued trend toward posterior-only approaches for achieving spinal deformity correction of idiopathic scoliosis. We present a posteriorly based correction technique and en bloc translation reduction maneuver that can be useful in the management of kyphoscoliosis.

OBSERVATIONS
A 50-year-old female with a past medical history of untreated adolescent idiopathic scoliosis since she was 12 years old presented to the clinic for evaluation of progressive thoracolumbar spinal deformity and worsening mid-to-low back pain. Standing scoliosis radiographs shows an 85° left lumbar curve with an apex at the L1–2 disk. There was a compensatory 58° right thoracic curve with an apex at T9, a −1.4 cm central vertical axis, and a focal kyphotic deformity of 86° from T11–L3 with a corresponding apex at the L1–2 disk. She was diagnosed with adult idiopathic scoliosis and indicated for a T9–L4 posterior spinal fusion with T11–L4 Smith-Peterson osteotomies. A simple en bloc reduction maneuver was used to translate the apex of the coronal deformity toward the midline and simultaneously correct the patient’s focal kyphosis.

LESSONS
A construct-to-construct biplanar cantilever technique is ideal for the treatment of kyphoscoliosis and can provide effective deformity correction in both the sagittal and coronal planes.
Clival intraosseous myxoma treated with an endoscopic endonasal approach: illustrative case
Authors: Porwal Mokshal H. , Aaronson Daniel M. , Razzak Abrahim N. , Zwagerman Nathan T. 
Published: April 2023

BACKGROUND
Solitary lesions of the clivus, especially nonchordomatous ones, are exceptionally rare pathologies representing only 0.1%–0.2% of intracranial tumors that may present diagnostic and therapeutic challenges. Intraosseous myxomas are benign tumors arising from mesenchymal cells with an unknown pathophysiology.

OBSERVATIONS
In this article, a 15-year-old male with clival intraosseous myxoma who was treated via an endoscopic endonasal surgical approach is presented. The patient became symptomatic after a baseball struck his head, leading to throbbing headaches and visual difficulties for tracking objects. Examination noted diplopia, cranial nerve VI palsy, and ptosis. After imaging revealed a tumor extending to the left cavernous sinus with bulging of the dorsal clivus against the basilar artery/ventral pons, resection was performed. Postoperatively, the patient noted ocular motility and alignment improvement without further complications.

LESSONS
Clival masses present with symptoms from compromised neurovascular structures including visual disturbances and trigeminal sensory deficits. Given the rarity of these entities, patients may postpone further treatment until workup; this patient was misdiagnosed for possible concussion until several weeks passed. A PubMed database review of cranial myxoma cases was conducted to identify solitary clival intraosseous myxoma cases. This case is one of the few in which this pathology was treated through an endoscopic endonasal operative approach without complications, demonstrating its safety and effectiveness.
Acute traumatic dural arteriovenous fistula of the superior sagittal sinus: illustrative case
Authors: Pryce Mitchell L. , Chung K. H. Carlos , Zeineddine Hussein A. , Dawes Bryden H. 
Published: April 2023

BACKGROUND
Dural arteriovenous fistulas (dAVFs) are aberrant vascular communications between meningeal arteries and venous sinuses or cortical veins. dAVF pathogenesis is incompletely understood; however, formation likely occurs as a result of angioneogensis.

OBSERVATIONS
A 78-year-old man presented after trauma with basal and cortical subarachnoid hemorrhage (SAH). Computed tomography revealed a parietal bone fracture overlying the superior sagittal sinus (SSS). Catheter angiography performed within 24 hours of the injury demonstrated an SSS dAVF supplied by the middle meningeal artery, adjacent to the fracture.

LESSONS
The authors present the case of an acute traumatic dAVF adjacent to a calvarial fracture. In this case, the authors proprose that the underlying pathogenesis is suggestive of direct vessel injury rather than the pathway commonly associated with this pathology.
Mengurai Kesenjangan Layanan Publik bagi Penyandang Disabilitas di Masa Pandemi: Studi Kasus Kabupaten Ponorogo
Authors: Febriyan Deby , Ma'ruf Muhammad Farid , Pradana Galih Wahyu , Megawati Suci 
Published: April 2023

Penyandang disabilitas dengan jenis disabilitas yang berbeda merupakan salah satu kelompok yang rentan terhadap infeksi virus covid-19. Dalam menghadapi covid-19 dan untuk penyandang disabilitas, pemerintah telah mengeluarkan kebijakan pencegahan. Regulasi ini harus diimplementasikan secara benar, dikarenakan individu dengan disabilitas memerlukan bantuan untuk melakukan aktivitas mereka karena keterbatasannya. Sehingga pendidikan mengenai protokol kesehatan menjadi sangat penting bagi penyandang disabilitas. Penelitian ini merupakan penelitian deskriptif kualitatif dengan pengumpulan data melalui studi literature, observasi, focus group discussion dan wawancara mendalam. Tujuan dari penelitian ini adalah untuk menguraikan strategy dari pemerintah daerah untuk mengedukasi protokol kesehatan untuk orang dengan disabilitas mental melalui optimalisasi Lembaga sosial di Ponorogo. Hasil penelitian ini mengungkapkan bahwa pemerintah setempat, termasuk juga penyandang disabilitas, mempunyai peran yang signifikan dalam menjalankan protokol kesehatan masyarakat. Edukasi protokol kesehatan untuk penyandang disabilitas dapat dilakukan antara lain dengan a) mengikutsertakan pembicara bahasa isyarat; (b) menyusun panduan pelaksanaan komunikasi dan penyediaan informasi yang inklusif, dan (c) membuat pedoman layanan untuk kelas daring. Edukasi protokol kesehatan dilakukan secara langsung dan tidak langsung. Partisipasi dari lembaga sosial non pemerintah merupakan salah satu cara untuk menerapkan protokol kesehatan bagi penyandang disabilitas di Kabupaten Ponorogo. Komunitas Rumah Harapan Karangpatihan adalah salah satu lembaga non pemerintah yang secara langsung aktif dalam edukasi penyandang disabilitas untuk protocol kesehatan di desa mereka. Edukasi bagi keluarga penyandang disabilitas dilakukan secara informatif. Dalam rangka membatasi interaksi langsung, aktivis Rumah Harapan sering mengkoordinasikan dukungan sosial dari berbagai pihak. Namun sangat disayangkan, pengoptimalan proses edukasi protokol kesehatan untuk penyandang disabilitas tidaklah terkoordinasi dengan baik antara rumah harapan dengan otoritas terkait yang ada di Kabupaten Ponorogo. Bagaimanapun juga, jelas bahwa penyandang disabilitas dalam aktivitas keseharian mereka tidak menerapkan protokol kesehatan.
The Policy of Coastal Waste Management: Case Study In Demak Regency
Authors: Masrohatun Masrohatun 
Published: April 2023

The excessive amount of waste piles has been a challenge for Indonesia. Moreover, it has worse impact on coastal communities as rob takes place. Hence, this study aims to unveil the forms of coastal community waste management and local government policy. Using qualitative method and case study approach, it was found that coastal communities shared the same understanding of waste. They perceived it as discarded substance, both organic and inorganic, after its primary use. Further, coastal communities disposed of the waste by getting it burnt, buried, thrown into rivers, sold, and saved in waste banks. In dealing with waste problems, the government issued policies by signing cooperation agreements and encouraging residents to have waste management literacy. However, many village governments did not have any specific policy on waste management.
Evolución perinatal y sobrevida a cinco años en niños con diagnóstico prenatal de síndrome de hipoplasia de ventrículo izquierdo
Authors: Cisternas O. Daniela , Terra V. Rodrigo , Aguilera P. Susana , Enríquez G. Gabriela , Rodriguez A. Juan Guillermo 
Published: April 2023

El síndrome de hipoplasia de ventrículo izquierdo (SHVI) es una cardiopatía congénita de baja prevalencia y alta letalidad. Objetivo: determinar la evolución perinatal y sobrevida al año y cinco años de fetos con diagnóstico prenatal de SHVI. Pacientes y Método: Estudio de cohorte prospectivo de todos los fetos con SHVI ingresados al Centro de Referencia Perinatal (CERPO) nacidos entre enero 2008 y diciembre 2017. Se obtuvieron datos demográficos y clínicos perinatales de la base de datos de CERPO. Al año y quinto año de edad, se realizó encuesta telefónica para conocer el tratamiento quirúrgico y sobrevida. Resultados: Se ingresaron 1.573 pacientes a CERPO, 899 con cardiopatías congénitas, confirmándose diagnóstico prenatal de SHVI en 7% (110/1.573). El promedio de edad gestacional al diagnóstico y la mediana al ingreso fue 26+3 y de 32+3 semanas respectivamente. 89% nacieron vivos, 90% a término y 57% por cesárea. La mediana de peso al nacer fue 3.128 gramos. 89% sobrevivió al periodo prenatal, 50% al periodo neonatal precoz, 33% al periodo neonatal tardío, 19% el primer año y 17% a los 5 años. Conclusiones: En este centro, la sobrevida al año y cinco años de fetos con diagnóstico prenatal de SHVI fue 19% y 17% respectivamente. Es importante que la consejería prenatal considere publicaciones basadas en casuísticas locales, con diagnóstico prenatal, postnatal y de aquellos que alcanzan la cirugía, para entregar información más precisa a los padres.
Determinants of Emergency Nurse Readiness for Emerging Infectious Diseases
Authors: Laksmi Ida Ayu Agung , Udaksana I Made Adi Wahyu , Susila I Made Dwie Pradnya 
Published: April 2023

Emerging infectious diseases are infectious diseases that appear and increase so rapidly that they can be said to be epidemics or non-natural disasters. As the front line, nurses are faced with uncertainties that increase the risk of exposure to disease, so preparedness is needed. This study aims to analyze the factors that affect the preparedness of emergency nurses in dealing with patients with emerging infectious diseases. This study is a correlational analytic study involving 109 emergency nurses in Bali. Data were collected through an online survey using a general questionnaire on demographic factors, a questionnaire on nurses' knowledge of EID, and a questionnaire on nurse preparedness in dealing with EID that had been tested for validity and reliability. The results of the bivariate analysis using the Spearman rank test showed that only the availability of personal protective equipment (p-value 0.007, p < α (0.05) and nurses' knowledge had a significant correlation with emergency nurse preparedness in dealing with patients with emerging infectious diseases (p-value 0.005, p < α (0.05). Therefore, it can be suggested to the hospital management in providing opportunities for emergency nurses to receive training related to emergencies in dealing with emerging infectious diseases and increase the assurance of the availability of adequate personal protective equipment (PPE).
Pengaruh Kualitas Pelayanan Dan Harga Terhadap Kepuasan Pelanggan Extra Qilo Laundry Kiloan Di Kota Batam
Authors: Manullang Nelli Riama , Heryenzus Heryenzus 
Published: April 2023

Bisnis Laundry adalah salah satu organisasi yang bergerak di bidang jasa dan saat ini tersebar luas secara lokal, pelayanan yang diberikan ialah mencuci, menyetrika, dan dry cleaning. Kepuasan pelanggan adalah tingkat pelayanan atau kualitas produk. Faktor kepuasan pelanggan yaitu, ada perbedaan harga dan kualitas pelayanan. Penelitian ini bermaksud untuk memutuskan bagaimana pengaruh kualitas pelayanan dan harga terhadap kepuasan pelanggan Extra Qilo Laundry Kiloan Di Kota Batam. Penelitian ini menggunakan analisis deskriptif kuantitatif, populasi berasal dari pelanggan Extra Qilo Laundry Kiloan Di Kota Batam. Adapun pengambilan sampel menggunakan metode accidental sampling, sampel yang diambil peneliti adalah 100 responden. Dalam pengumpulan informasi peneliti menyebarkan kuesioner dengan mengajukan pertanyaan atau pernyataan kepada responden. Teknik analisis dilakukan dengan metode analisis regresi berganda, uji asumsi klasik, uji koefisien determinasi,Uji t dan Uji f dengan pengolahan data menggunakan SPSS versi 25. Analisis hasil peneltian ini dapat di simpulkan bahwa kualitas pelayanan berpengaruh secara parsial dan signifikan terhadap kepuasan pelanggan dengan nilai t hitung 9,194 > t tabel 1,984. Kualitas pelayanan dan harga secara simultan berpengaruh signifikan terhadap kepuasan pelanggan dengan F hitung 109,834 lebih besar F tabel 3,09 dan nilai signifikasi 0,000 < 0,05.
Pengaruh Current Ratio, Return On Assets, dan Total Assets Turnover Terhadap Harga Saham Pada Perusahaan Makanan dan Minuman Yang Terdaftar di Bursa Efek Indonesia (BEI) Periode 2017-2021
Authors: Winata Suryadi , Selfiyan Selfiyan , Suhendra Suhendra , Samara Aldi 
Published: April 2023

Tujuan dari penelitian ini ialah untuk mengetahui pengaruh current ratio (CR), return on assets (ROA) dan total asset turnover (TATO) terhadap harga saham perusahaan makanan dan minuman yang terdaftar di Bursa Efek Indonesia (BEI) di Indonesia. pasar saham 2017 – 2021.
Metode penelitian ini mengadopsi metode kuantitatif. Data dalam penelitian ini didasarkan pada data sekunder yang menggambarkan laporan tahunan perusahaan makanan dan minuman yang terdaftar di Bursa Efek Indonesia (BEI) dari tahun 2017 hingga tahun 2021. Teknik pengambilan sampel dalam penelitian ini menggunakan teknik purposeful sampling. Metode analisis yang digunakan dalam penelitian ini adalah pengujian hipotesis klasik, pengujian regresi linier berganda, pengujian korelasi berganda dan pengujian hipotesis. -tes-t dan tes-F. Berdasarkan hasil yang dianalisis dalam penelitian ini, CR, ROA, dan TATO secara simultan berpengaruh terhadap harga saham perusahaan makanan dan minuman yang terdaftar di Bursa Efek Indonesia (BEI) selama periode 2017-2021. Terkadang CR dan ROA berdampak signifikan terhadap harga saham, sedangkan TATO terkadang berdampak negatif terhadap harga saham.