bluuebunny/crossref_metadata_2025_split huggingface dataset:
Polylactic Acid-Based In-house Three-Dimensional-Printed Intraoperative Surgical Model is a Time- and Cost-efficient Approach for Mandibular Reconstruction
Authors: Bangun Kristaninta , Tania Vika , Cendrick Windy , Halim Jessica , Atmodiwirjo Parintosa , Ramadan Mohamad R. , Kreshanti Prasetyanugraheni 
Published: August 2023

Abstract
Background The advanced development of computer-assisted design/manufacturing (CAD/CAM) technology aids in the process of producing patient-specific template for intraoperative dissection and fixation guide. To date, CAD/CAM technology has been greatly used in reconstructive mandibular cases to enhance accuracy, reduce operation time, and minimize possible complications. However, this technology was believed to be cost- and time-inefficient, limiting widespread use in several institutions.
Methods This study displayed five case series incorporating in-house three-dimensional (3D)-printed models. 3D imaging was retrieved from computed tomography scan Digital Imaging and Communications in Medicine files, which was processed to STL (Stereo-lithography) format to recreate a symmetrical postoperative design. The rendered 3D file was then printed with the in-house printer using polylactic acid (PLA) material. A sterilized 3D-printed model was used as intraoperative guidance for plate bending and positioning. The process, time, and cost of each 3D model production were documented.
Results A total of 100% success rate was observed in processing 3D-printed model in all cases, with no fail in printing. The printing time on average took 7 hours, 39 minutes (ranging from 5 hours 59 minutes up to 9 hours 43 minutes) and cost spent on average was approximately $1.83 on each print (ranging from $1.69 up to $2.10). The in-house 3D printer costs approximately $750, which is compact and can be easily purchased online.
Conclusion CAD/CAM technology is a cost- and time-efficient approach, in addition to its renowned benefits in increasing surgical accuracy, reducing operation time, improving postoperative look, and minimizing complications. We suggest the implementation of in-house printed PLA-based 3D surgical guide for mandibular reconstructions.
Bloqueio supracondilar de nervo radial versus bloqueio de hematoma de fratura. Comparativo de sua eficácia em casos de fraturas do terço distal do rádio
Authors: Maia Guilherme de Albuquerque Souza , Cunha Jean Castro , Feijó Carolina Queiroz , Leal Daniel Mendes , Moreira Juan Javier , Herrero Carlos Fernando Pereira da Silva 
Published: August 2023

Resumo
Objetivo O estudo compara a eficácia analgésica de duas técnicas para realizar redução incruenta: o bloqueio de hematoma da fratura e o bloqueio supracondilar de nervo radial.
Métodos Quarenta pacientes com fraturas do terço distal do rádio, que necessitassem redução, foram selecionados em um ensaio clínico quasi-randomizado, para receber uma das técnicas anestésicas. Todos os pacientes assinaram o termo de consentimento ou assentimento, com exceção daqueles que não desejassem participar do estudo, tivessem lesão neurológica, com contraindicação ao procedimento na sala de emergências, ou com contraindicação ao uso da lidocaína. Para aferir a analgesia foi utilizada a escala numérica da dor em quatro momentos distintos: pré-bloqueio, pós-bloqueio, durante a redução e após a redução; em seguida, foram calculadas três diferenças: a primeira entre antes e após o bloqueio; a segunda entre durante a redução e após o bloqueio; e a terceira entre antes do bloqueio e após a redução.
Resultados Os grupos do bloqueio de hematoma de fratura e bloqueio supracondilar apresentaram respectivamente os seguintes valores médios: 3.90 (1–10) e 3.50 (-6–10) na diferença 1; 4.35 (-5–10) e 5.00 (-3–10) na diferença 2; e 4.65 (1–10) e 3.80 (-3–10) na diferença 3.
Conclusão As duas técnicas se provaram eficientes para analgesia, com discreta superioridade do bloqueio de hematoma, mas sem significância estatística.
Tratamento das pseudoartroses infectadas da tÍbia pelo mÉtodo de Ilizarov associado ao curativo de Orr
Authors: Ferreira Wladimir Querubino , Ferreira Dwilian José , Fontoura Ricardo Stival , Peres João Vieira , Rocha Danilo Simões , Lima João Pedro Leite 
Published: August 2023

Resumo
Objetivo Analisar os resultados e os dados clínicos e epidemiológicos do tratamento das pseudoartroses infectadas da tíbia pelo método de Ilizarov associado ao curativo de Orr.
Métodos Para analisar os dados de n = 43 pacientes com diagnóstico de pseudoartrose infectada da tíbia foram aplicados métodos estatísticos descritivos e inferenciais e os resultados ósseos e funcionais foram avaliados de acordo com os critérios de avaliação de Paley. As variáveis qualitativas foram apresentadas por distribuição de frequências absolutas e relativas. As variáveis quantitativas foram apresentadas pelo teste de DAgostino-Pearson.
Resultados Foi encontrado que 37 (86,04%) eram do sexo masculino, 6 (13,95%) femininos. A faixa etária mais frequente entre os pacientes foi de 50 a 59 anos (25.6%), p-valor = 0.8610. O tempo de tratamento é maior no tratamento trifocal (23.8 meses) quando comparado com o Bifocal (15.6 meses), p-valor =0.0010* (altamente significante). Os resultados ósseos excelentes representaram 72,09%, 23,25% foram de resultados considerados bons. Os resultados funcionais considerados excelentes foram 55,81%, os resultados bons foram 6,97%, resultados regulares foram 27,90. O curativo com gaze vaselinada (curativo de Orr) mostrou-se eficaz, alcançando assim a cicatrização das feridas com cobertura de partes moles em todos os pacientes avaliados.
Conclusões O método de Ilizarov proporcionou uma mudança substancial no tratamentos das infecções ósseas, especialmente das pseudoartroses infectadas. A versatilidade deste método se transformou em uma ferramenta eficaz, permitindo a cura do processo infeccioso, bem como correção das possíveis deformidades e do encurtamento.
Unilateral Repair of an Avulsion Fracture of the Caudal Cruciate Ligament Origin Combined with a Ruptured Cranial Cruciate Ligament in a Dog
Authors: Pike A.A. , Balfour R.J. 
Published: August 2023

AbstractCaudal cruciate ligament (CaCL) femoral avulsion fractures are rarely documented, and a true incidence is unclear. A literature search revealed very few cases of a CaCL avulsion fracture or rupture combined with a cranial cruciate ligament (CrCL) rupture. Only a single case report described surgical treatment of this combination by fragment removal and stifle stabilization with an extracapsular suture. A 1-year-old female spayed Labrador Retriever presented with a hindlimb lameness. Examination revealed cranial drawer of the stifle, consistent with CrCL rupture. Stifle effusion, as well as a bone opacity seen in the trochlear groove, was evident on radiographs. At surgery, arthrotomy revealed a torn CrCL as well as an avulsion fracture of the CaCL origin from the medial femoral condyle. The avulsion fracture was reduced, and three 0.035-inch Kirschner's wires (K-wires) were placed in a divergent fashion through the fragment into the medial femoral condyle. A tibial plateau leveling osteotomy (TPLO) was then performed. Six-week recheck radiographs showed good healing of the TPLO as well as the repaired avulsion fracture, despite breakage of one of the K-wires. The dog was mildly lame at the 6-week follow-up and subsequently improved to clinically normal on the limb at 8-month follow-up with optimal bone healing on radiographs. To the authors' knowledge, this is the first case report to describe a CaCL avulsion fracture repair with K-wires combined with a TPLO for a torn CrCL, with an excellent clinical outcome.
Tratamento das lesões condrais no joelho
Authors: Filho José Paulo Aramburu Gabbi , Sousa Eduardo Branco de 
Published: August 2023

ResumoAs lesões da cartilagem articular são comuns e levam à deterioração precoce da articulação e ao desenvolvimento da osteoartrite. As técnicas de reparo da cartilagem articular visam a formação de um neo-tecido cartilaginoso capaz de suportar carga articular e evitar a progressão da degeneração. Há várias técnicas disponíveis para esse fim, como a microfratura e o transplante de condrócitos. Entretanto muitas vezes o desfecho do procedimento é a formação de fibrocartilagem, que não possui a mesma resistência mecânica do tecido cartilaginoso. Em outros procedimentos, nos quais é realizado enxerto osteocondral autólogo, há risco de morbidade associada ao procedimento, além da disponibilidade limitada de tecido. Por esse motivo, o transplante osteocondral, utilizando enxertos a fresco ou congelados tem sido utilizado para lesões de maior volume. Por fim, novas técnicas utilizando fragmentos de cartilagem picada ou particulada, assim como o uso de células tronco mesenquimais se apresentam como promissores. O objetivo desse artigo é realizar uma atualização dos procedimentos para tratamento das lesões condrais do joelho.
O acetábulo sofre remodelamento após a osteotomia derrotatória varizante em pacientes com doença de Perthes?
Authors: Deo Nitish Bikram , Agarwal Anil 
Published: August 2023

Resumo
Objetivo Investigamos o efeito do estágio da doença, idade do paciente e contorno final da cabeça femoral no contorno do acetábulo após a osteotomia derrotatória varizante (VDRO) do fêmur proximal na doença de Perthes unilateral.
Métodos O estudo é uma análise retrospectiva de prontuários de 23 crianças com idade ≥ 6 anos com doença de Perthes unilateral que foram submetidas ao procedimento primário de VDRO para contenção. O índice acetabular (AI) e o ângulo da borda central (CEA) foram calculados bilateralmente em radiografias pré-operatórias e de acompanhamento e submetidos à comparação estatística.
Resultados Os pacientes eram 15 meninos e oito meninas. À VDRO, seis quadris estavam no estágio de Waldenström modificado Ib, oito no estágio IIa e nove no estágio IIb. A média de idade à intervenção cirúrgica foi de 8,7 anos. A duração média do acompanhamento foi de 3,5 anos. Todas as cabeças femorais estavam consolidadas no último acompanhamento e os graus finais de Stulberg foram I = 3, II = 8, III = 7 e IV = 5. Havia displasia acetabular significativa do lado acometido no período pré-operatório. No acompanhamento, os pacientes operados apresentaram elevação significativa de AI e redução de CEA. Não houve remodelamento acetabular significativo nos quadris acometidos durante o acompanhamento, mesmo em crianças operadas em idade menor (< 8 anos) ou estágios iniciais (estágio Ib ou IIa). O remodelamento do acetábulo também não correspondeu ao grau final de Stulberg.
Conclusão A VDRO do fêmur do quadril acometido não levou à melhora significativa da displasia acetabular, mesmo quando a cirurgia foi realizada nos estágios iniciais da doença ou em pacientes mais jovens. Alterações acetabulares residuais também foram observadas mesmo com graus de Stulberg favoráveis.
A comparison of growth of a vulnerable species, common carp, Cyprinus carpio (Actinopteri: Cyprinidae), from two different reservoir types in the same river basin
Authors: Dereli Hakkı , Bayhan Bahar 
Published: August 2023

Context The mechanisms underlying regional differences in growth parameters of common carp, Cyprinus carpio Linnaeus, 1758 (Actinopteri: Cyprinidae), are not yet fully understood, because comparisons among them have been made post hoc. Aims To simultaneously compare growth of common carp between sexes and between regions: Demirköprü Reservoir (DR) and Marmara Lake (ML), which have different structures (lowland type vs highland type) and are proximate to each other in the same river basin (Gediz River Basin). Methods Length-frequency distributions, length–weight relationships and three growth models (von Bertalanffy growth function (VBGF), Gompertz growth function (GGF) and Robertson growth function (RGF)) were used for both sexes and all individuals in reservoirs. Key results As none of the best-fitting models used among these growth models clearly suggested a ‘clear winner’ (Akaike’s weight (wi) > 0.9), the model-averaged multi-model inference (MMI) was used for the first time for common carp. Conclusions Asymptotic length obtained from MMI for all individuals in ML (lowland type) was statistically higher than that in DR (highland type) (P < 0.05). Implications Based on the maximum observed length and the mean L∞ obtained from MMI, the common carp population in the DR can be considered threatened by overfishing.
Numerical calculation and analysis of a novel complex impedance sensing approach for in-flow droplet detection utilizing the C4D technique
Authors: Nguyen Van Phu , Bao Hoang Anh , Tran Thanh Hang , Nguyen Thu Hang , Bui Thu Hang , Do Quang Loc 
Published: August 2023

Abstract
This study proposed a C4D sensor structure with a novel approach utilizing the complex impedance analysis method, which includes both resistance and reactance analysis. The complex impedance analysis method provides additional information to characterize the electrical properties of solutions and strange objects moving in the fluidic channel, thus enhancing the sensitivity of conventional C4D structure. In addition, the effects of the fluidic properties, object size, excitation frequency, and sensor geometry on the performance of the proposed C4D sensor were investigated. The proposed sensor system used the finite element method analysis to investigate the performance of the proposed method. The simulation results show that the largest resistance change is approximately 27 kΩ while the largest reactance change is about 10 kΩ according to the passage of a 400 μm radius oil droplet over the sensing area in the NaCl solution channel. Furthermore, this work indirectly verifies the possibility and feasibility of the proposed impedance analysis method by utilizing the conventional C4D structure thanks to its advantages and lays a good foundation for future research work.
Exactly self-similar blow-up of the generalized De Gregorio equation
Authors: Zheng Fan 
Published: August 2023

Abstract
We study exactly self-similar blow-up profiles for the generalized De Gregorio model for the three-dimensional Euler equation:

w
t

+
a
u

w
x

=

u
x

w
,

u
x

=
H
w
.

We show that for any

α
∈
(
0
,
1
)

such that

|

a
α

|

is sufficiently small, there is an exactly self-similar C

α
solution that blows up in finite time. This simultaneously improves on the result in Elgindi and Jeong (2020 Arch. Ration. Mech. Anal.
235 1763–817) by removing the restriction

1

/

α
∈

Z

and Chen et al (2021 Commun. Pure Appl. Math.
74 1282–350), which only deals with asymptotically self-similar blow-ups.
Deuterium supersaturated surface layer in tungsten: ion energy dependence
Authors: Nishijima D. , Tokitani M. , Nagata D. , Schwarz-Selinger T. , Založnik A. , Chang F. , Doerner R.P. , Patino M.I. , Simmonds M.J. , Baldwin M.J. , Tynan G.R. 
Published: August 2023

Abstract
Properties of deuterium (D) supersaturated surface layers (DSSLs) formed in tungsten (W), such as thickness, internal microstructures, and D retention, are experimentally investigated as a function of the incident ion energy, E
i. W samples were exposed to D plasmas in the PISCES-A linear plasma device in a range of E
i ∼ 45–175 eV, while other plasma exposure parameters were fixed: sample temperature, T
s, ∼423 K, ion flux, Γi, ∼1.2 × 1021 m−2s−1, and fluence, Φi, ∼3.0 × 1024 m−2. High-resolution, cross-sectional, transmission electron microscopy observations confirm that (1) a DSSL forms even at the lowest E
i ∼ 45 eV, (2) the DSSL thickness, Δt
DSSL, is found to decrease with decreasing E
i from ∼11–12 nm at E
i ∼ 175 eV to ∼5–6 nm at ∼45 eV, and to agree with approximately the maximum implantation depth calculated using SDTrimSP, and (3) high-density D nanobubbles with a diameter of ∼1 nm or less exist inside the DSSL, which is deemed to validate a theory-predicted vacancy stabilization process due to trapping of a solute D atom(s). Utilizing a D areal density of ∼4.2 × 1019 m−2 in the first 14 nm from the surface at E
i ∼ 75 eV from nuclear reaction analysis and the measured E
i dependence of Δt
DSSL, our previous laser-induced breakdown spectroscopy data is updated: both dynamic and static D retention increase with decreasing E
i, and the D/W atomic fraction during plasma exposure reaches ∼0.3 at E
i ∼ 45 eV. A possible DSSL formation mechanism is proposed.
Impact of uterine deformation induced by applicator on brachytherapy dosimetric value: an uterine-mimicking-phantom study
Authors: Seiri Mahnaz , Jaberi Ramin , Solgi Razieh , Shakeri Mahsa , Ghadiri Hossein 
Published: August 2023

Abstract
Brachytherapy (BT) is subjected to uncertainties from
imaging, treatment planning, and anatomical variations. It is
necessary to identify the uncertainties, their magnitude, and their
impact on the overall uncertainty of dose delivery. The aim of the
present phantom-based study is to investigate the deformation of the
uterus anatomy induced by BT applicator insertion and the
relationship between dose and location of the inserted applicator. A
novel flexible phantom was designed based on female pelvic anatomy
by the 3D printing process to simulate the deformation and movement
of the uterine during the BT process. The applicator was inserted
into the uterus and in order to simulate the uterus motion, the
phantom was moved in four directions, right, left, down, and up. The
CT and ultrasound images were obtained. A two-stage registration
algorithm was designed to register the ultrasound and CT images in
order to calculate the applicator displacements map. This map was
used to calculate delivered dose error to uterus and rectum and to
correct the planned dose values in treatment planning procedure. The
results showed that in a planned D90 (dose) of 9.4 Gy for the
uterus and maximum dose of 1.8 Gy to the rectum, movement of
applicator leads to a big deviation in final delivered doses. After
the applicator moved to the right and left directions, the D90
delivered to the uterus was 6.2 Gy and 5.6 Gy, respectively.
Moreover, by moving downwards and upwards, the uterus received 0.4
and 1.2 Gy lower than 9.4 Gy. Similarly, the maximum dose to the
rectum in right, left, down, and up directions after applicator
movement were 3.4 Gy, 3.3 Gy, 3.7 Gy and 3.2 Gy, respectively
which highlighted the higher delivered dose to the rectum. The
results of the study demonstrate that applicator displacement can
lead to uterine underdosing and also increase the risk of rectum
irradiation. Ultimately, image-guided brachytherapy and using image
registration can increase the accuracy of treatment and reduce the
errors of delivered dose to target volume and organs at risk,
especially in uterus cancer.
Bone-mimicking scaffold based on silk fibroin incorporated with hydroxyapatite and titanium oxide as enhanced osteo-conductive material for bone tissue formation: fabrication, characterization, properties, and in vitro testing
Authors: Watcharajittanont Nattawat , Tabrizian Maryam , Ekarattanawong Sophapun , Meesane Jirut 
Published: August 2023

Abstract
Bone-mimicking scaffolds based on silk fibroin (SF) mixed with hydroxyapatite nanoparticles (HA NPs) and titanium oxide (TiO2) nanoparticles were created as materials for bone formation. Six scaffold groups were fabricated: S1 (SF), S2 (Silk + (HA: TiO2; 100: 0)), S3 (Silk, (HA: TiO2; 70: 30)), S4 (Silk + (HA NPs: TiO2; 50: 50)), S5 (Silk + (HA: TiO2; 30: 70)), and S6 (Silk + (HA NPs: TiO2; 0:100)). Scaffolds were characterized for molecular formation, structure, and morphology by Fourier transform infrared spectroscopy, element analysis, and X-ray diffraction. They were tested for physical swelling and compressive modulus. Scaffolds were cultured with MC3T3 and tested in vitro to evaluate their biological performance. The results showed that scaffolds with HA and TiO2 demonstrated molecular interaction via amide I and phosphate groups. These scaffolds had smaller pore sizes than those without HA and TiO2. They showed more swelling and higher compressive modulus than the scaffolds without HA and TiO2. They exhibited better biological performance: cell adhesion, viability, proliferation, alkaline phosphatase activity, and calcium content than the scaffolds without HA and TiO2. Their porous walls acted as templates for cell aggregation and supported synthesis of calcium secreted from cells. S3 were the most suitable scaffolds. With their enhanced osteo-conductive function, they are promising for bone augmentation for oral and maxillofacial surgery.
Tundra fire increases the likelihood of methane hotspot formation in the Yukon–Kuskokwim Delta, Alaska, USA
Authors: Yoseph Elizabeth , Hoy Elizabeth , Elder Clayton D , Ludwig Sarah M , Thompson David R , Miller Charles E 
Published: August 2023

Abstract
Rapid warming in Arctic tundra may lead to drier soils in summer and greater lightning ignition rates, likely culminating in enhanced wildfire risk. Increased wildfire frequency and intensity leads to greater conversion of permafrost carbon to greenhouse gas emissions. Here, we quantify the effect of recent tundra fires on the creation of methane (CH4) emission hotspots, a fingerprint of the permafrost carbon feedback. We utilized high-resolution (∼25 m2 pixels) and broad coverage (1780 km2) airborne imaging spectroscopy and maps of historical wildfire-burned areas to determine whether CH4 hotspots were more likely in areas burned within the last 50 years in the Yukon–Kuskokwim Delta, Alaska, USA. Our observations provide a unique observational constraint on CH4 dynamics, allowing us to map CH4 hotspots in relation to individual burn events, burn scar perimeters, and proximity to water. We find that CH4 hotspots are roughly 29% more likely on average in tundra that burned within the last 50 years compared to unburned areas and that this effect is nearly tripled along burn scar perimeters that are delineated by surface water features. Our results indicate that the changes following tundra fire favor the complex environmental conditions needed to generate CH4 emission hotspots. We conclude that enhanced CH4 emissions following tundra fire represent a positive feedback that will accelerate climate warming, tundra fire occurrence, and future permafrost carbon loss to the atmosphere.
The shape of chromatin: insights from computational recognition of geometric patterns in Hi-C data
Authors: Raffo Andrea , Paulsen Jonas 
Published: August 2023

AbstractThe three-dimensional organization of chromatin plays a crucial role in gene regulation and cellular processes like deoxyribonucleic acid (DNA) transcription, replication and repair. Hi-C and related techniques provide detailed views of spatial proximities within the nucleus. However, data analysis is challenging partially due to a lack of well-defined, underpinning mathematical frameworks. Recently, recognizing and analyzing geometric patterns in Hi-C data has emerged as a powerful approach. This review provides a summary of algorithms for automatic recognition and analysis of geometric patterns in Hi-C data and their correspondence with chromatin structure. We classify existing algorithms on the basis of the data representation and pattern recognition paradigm they make use of. Finally, we outline some of the challenges ahead and promising future directions.