bluuebunny/crossref_metadata_2025_split huggingface dataset:
Health status and behavior influences to sleep quality among community-dwelling elderly in Chanthaburi Province, Thailand
Authors:   , Siripanich Chanisa 
Published: September 2023

Purpose – The trend of sleep disorder is typically more common in aged changes due to health condition changes leading to poor sleep satisfies. Therefore the purpose of this study was to examine the rate and factors associated to sleep quality among Community-Dwelling Elderly in Chanthaburi Province, Thailand. Design/methodology/approach – A cross-sectional was conducted in 208 elderly by multi-stage sampling. All participants were interviewed by the questionnaire. sleep quality was assessed by Pittsburgh sleep quality index (PSQI). Sleep quality score ≥ 5 indicating poor sleep quality. Chi-square tests and Multivariate logistic regression models were performed to find significant associations. Findings – We found that 208 participants found 66.3% were poor sleep quality with score ≥ 5 PSQI. The adjusted odds ratio (AOR) for gender, age, and BMI, the multivariate logistic regression model, presented that elders had never participated social activities was increased poor sleep quality 5.962-fold odds (p.value<0.05; 95% CI 1.459 – 24.361). Elders had never prayed before sleep was increased poor sleep quality 1.478-fold odds (p.value<0.05; 95% CI 0.273 – 0.838). Perception of musculoskeletal problem was increased poor sleep quality 2.288-fold odds (p.value<0.05; 95% CI 1.249 – 4.192). Bladder problem perception was increased poor sleep quality 2.618-fold odds (p.value<0.05; 95% CI 1.084 – 6.327). Depression was increased poor sleep quality 3.275-fold odds (p.value<0.05; 95% CI 1.179 - 9.095). Lastly, smoking was increased poor sleep quality 2.147-fold odds (p.value<0.05; 95% CI 1.062 – 4.340). Originality/value – Promoting intervention regulation strategies particularly improving social participation, health education to prevent chronic diseases, and engages the mental health among elderly are essential.
Integrated Communicative Health Literary(ICHL) among Thai type 2 diabetic patients in SamutSongkram Province Thailand: a case study of CHL towarddiabetes type outcome
Authors:   , Prabsangob Kantapong 
Published: September 2023

This multi –phasing study aimed to develop and evaluate an integrated communicative health literacy program (ICHL Program) for type 2 diabetic patients in Bangkonthee district, Samut Songkram province, Thailand. The study divided into four phases. Phase 1-2 : Cross sectional study was conducted using quantitative (n =415) and qualitative study (n =14) which aimed to assess the level of health literacy of the DM patients aged 50-80 years old and describing providers’ and patients’ perception towards promoting health literacy. Phase 3: Developing and implementing ICHL (based on the findings of cross-sectional study). Phase 4: Evaluating the effect of the ICHL. The cross-sectional study shown that the participants has moderate level of health literacy. The quasi experimental study was employed to evaluate the effect of the ICHL. 70 diabetes patients aged between 50 and 80 years, living in a rural Thai community was purposively selected and divided into two groups of 35 patients. Then, they were selected to be an intervention groups receiving the ICHL program and a control group receiving a regular health literacy promotion program. A questionnaire was used to assess socio-demographic characteristics, and self-care behavior. The 3-level Health Literacy Scale developed by Ishikawa was used to assess health literacy level. Patients’ blood sugars (HbA1c) were retrieved from hospital patient health records. The measurements of dependent variables were conducted three times: at baseline, after the intervention (three months), and during six months follow up. Descriptive statistic, Chi square, t-test, and repeated-measure ANOVA were used for data analysis. The finding showed the significant improvement in health literacy, self-care behavior, and HbA1c after 3 month participation in the program ( p-value <0.05), but not sustainable through 6 month participation. It was concluded that the Integrated Communicative Health Literacy program could enable diabetic patients to control their blood sugar, increase health literacy and enhance their self-care behavior to control their blood sugar.
Effectiveness of a personally-tailored oral care program on improving periodontal status among Thai persons with physical disabilities in Pathum Thani province, Thailand
Authors:   , Sermsuti-anuwat Nithimar 
Published: September 2023

The purpose of this study was to develop and evaluate the Personally-Tailored Oral Care Program on improving periodontal status among Thai persons with physical disabilities.

This quasi-experimental study was conducted at Independent Living Center, a community club for persons with disabilities in Pathum Thani province, Thailand from February to May 2018. Total of 80 members who registered in Ladlumkaeo district (control) and Thanyaburi district (intervention), Pathum Thani Province were included (each group comprising 40 participants). Data were analyzed by using Chi-square test, t-test and repeated measures analysis of variance.

The results, there were strongly significant difference in bleeding on probing (BOP), plaque index (PI) and oral health behavior knowledge mean score (p<0.001) and there was a significant difference in oral health literacy (p = 0.027) between the intervention and control group at the 12-week follow-up. Substantially significant differences in BOP, PI, OHB and OHL mean score were found within the intervention group after they received the Personally-Tailored Oral Care Program (p< 0.001).

The Personally-Tailored Oral Care Program was effective for improving periodontal condition and generated oral health behavior knowledge and oral health literacy among Thai persons with physical disabilities.
Relationship between workload and obesity among dentists in regional health no.8, Northeastern, Thailand
Authors:   , Gaysorn Satianpong 
Published: September 2023

Propose: Primary Objective is to find a relation between dentist’s workload and obesity while secondary objective is to find a relation between other independent factors and Obesity.

Design: This is a descriptive cross-sectional study with population of all 365 dentists in Regional Health no.8 area. From formulation, the sample size need at least 191 but will send out questionnaire to all individual in population in case of people unwillingness or unqualified for the study. Dental Workload questionnaire will adapted from ADA, Iowa, Utah, and Royal College of Dental Surgeons of Thailand. Other than that standardized questionnaires from WHO GPAQ, WHO Audit, WHO MPOWER, Ramathibodi Hospital Sleep Disorder Center, Mahidol University, and Bureau of Health Promotion. All questionnaires were sent to all MOPH hospital within Health Region No.8. There’s an envelope with stamp inside each questionnaire’s sealbag so that the participant or hospital staff will send back to the author without any fee.

Findings: 209 participants sent the survey back. Relationship between overall working time and working time in office hour and BMI are only little positive correlation while working time outside office hour and number of patient doesn't significantly related to BMI at all. Completing all request appointment and felt overworked leads to higher chance of being obesity and abdominal obesity.

Value: This study could be a supporting evidence if there’s an establishment of policy on protecting and improving Thai dentist’s quality of life.
Effects of short-term growth hormone administration on plasma leptin levels in normal and diet-induced obesity rats
Authors:   , Likitnukul Sutharinee 
Published: September 2023

Obesity has related to the alteration of hormonal profiles, i.e. growth hormone (GH), insulin and leptin. Because of the pleiotropic mechanisms of GH, it plays important roles both in the pathophysiological mechanisms and the therapeutic hormonal supplementation, which probably affected plasma leptin. The present research aimed firstly to demonstrate the effect of short-term GH administration on plasma leptin in 3 conditions; basal, meal-induced and fasting condition, from the rats with different adipose tissue mass. Secondly, to investigate short-term effect of GH on insulin sensitivity and body adiposity in control, diet resistant (DR) and diet-induced obesity (DIO) rats. In this regard, the rats were divided to control and hypercaloric (HC) diet-feeding rats. After 6 weeks of feeding period, HC diet-feeding rats were selected for DR and DIO rats. Exogenous GH (1 mg/kg, twice daily) was injected and compared with saline-treated rats. Short-term GH treatment decreased plasma leptin only in DIO rats that significantly occurred at 32 h after the first GH injection. The leptin response probably depended on the higher body adiposity in DIO rats than that of control and DR rats. For meal-induced plasma leptin, short-term GH treatment had no effect in all rats. For fasting condition, GH treatment attenuated the effect of fasting on plasma leptin in control and DR rats, which had the lower adiposity than that of DIO rats. Insulin resistance (IR) was induced by short-term GH treatment, which demonstrated by the higher fasting insulin and increased surrogate indexes of insulin resistance in DR rats, including the homeostasis model IR and adipose tissue IR. Therefore, we conclude that the effect of short-term GH treatment on plasma leptin might depend on body adiposity and energy status. These findings reveal the evidence of short-term GH treatment on plasma leptin and may suggest the short-term GH treatment as adjunctive therapy in obese stage.
Measurement of organisational innovativeness of public agencies in Asean
Authors:   , Thipayang Salinthip 
Published: September 2023

As public sector organisations strive to balance priorities to meet increasing public demands, they need to be more innovative and changes bureaucratic behaviors, administrative methods, and implementing new way of conducting routine work processes. This study combines both qualitative and quantitative empirical research methods with the objectives to 1) review how organisational innovativeness (OI) has been measured and identify the important factors affecting OI of public agencies, 2) develop and validate a suitable measurement framework model and indicators for measuring OI in ASEAN public agencies, 3) to create an online web-based application (POINTinno.com) to adequately measure OI, and 4) test how POINTinno.com was perceived by the potential users and assess its commercialisation potential. In order to be more innovative and competitive, public organisations require 1) innovative culture, 2) strong transformation leadership, 3) innovative strategy with effective followed-through mechanism to mitigate changes, 4) motivated and capable workforce, 5) sufficient resources and funds, 6) innovative management capability and practices, 7) effective performance monitoring and evaluation system, and 8) outreach collaborative networks and supportive external contexts and regulations to foster innovation. POINTinno.com was developed to assess OI across ASEAN and the results showed that the scales have high internal consistency and reliability with Cronbach’s Alpha values of 0.896 – 0.955 (n = 290). First order confirmatory factor analysis results revealed that the latent variables and indicators in POINT fitted the empirical data with indices of comparative fit index (CFI) of 0.997, Tucker-Lewis Index (TLI) of 0.995, chi-square χ2 (14, N = 290) = 20.024, p =.129, root mean square error of approximation (RMSEA) of 0.039, and standardized root mean squared residual (SRMR) of 0.011. Moreover, the observed factor loadings of the eight factors of POINT ranged from 0.662 - 0.902 and were significant at p <.01 indicating that the eight factors are the important indicators of public OI. User technology acceptance test of POINTinno.com revealed that the users were satisfied in using the application as a multi criteria decision analysis and decision support program with high mean average score of 4.12 (SD 0.771). The commercialisation analysis revealed that the NPV of the POINTinn.com was estimated at 1.60 million Baht, IRR=170%, and the estimated payback period of initial total investment at approximately 12 months. This research study contributes to a much needed empirically validated OI framework model as well as the development of a reliable tool to adequately measure, benchmark, and assess public OI in ASEAN developing countries.
Difference of some spermatozoa and seminal plasma proteins in good and poor freezability boar ejaculates
Authors:   , Rungruangsak Janyaporn 
Published: September 2023

The present study was performed to determine the differences of some seminal plasma proteins, i.e., glutathione peroxidase 5 (GPX5) and fibronectin 1 (FN1), and some spermatozoa proteins, i.e., triosephosphate isomerase (TPI) and ACRBP (acrosin binding protein), in the boar semen having good and poor freezability. The study was conducted by including 38 ejaculates in seminal plasma study and 32 ejaculates from spermatozoa study from 27 boars (Duroc=13, Landrace= 8, Yorkshire= 6). The semen was split into two portions. The first portion was centrifuged to separate the pellet of sperm from the seminal plasma. The samples were kept at −80 °C until protein extraction. The second portion was cryopreserved. After thawing, the ejaculates were classified into 3 groups according to their post-thawed sperm motility, i.e., good, moderate and poor. Post-thawed sperm motility in each group were 60.2 ± 1.67%, 29.3 ± 2.02% and 16.6 ± 2.17%, respectively. The samples were determined by using Western blot analysis. It was found that the level of FN1 in seminal plasma was higher in the semen with good than poor freezability (0.08±0.01 vs 0.05±0.01, respectively, P < 0.05), but did not differ significantly compared to semen with moderate freezability (0.07±0.01, P>0.05). Additionally, the level of FN1 in the seminal plasma was positively correlated with the post-thawed sperm progressive motility (r = 0.42, P = 0.009), total motility of the boar spermatozoa (r = 0.43, P = 0.007), VAP (r= 0.34, P=0.04), the proportion of bent tail sperm (r = 0.36, P = 0.03) and the proportion of coil tail sperm (r = 0.31, P = 0.05). GPX5 was not correlated with the post-thawed sperm qualities (P > 0.05). However, the levels of GPX5 was positively correlated with FN1 (r = 0.35, P = 0.03). For spermatozoa proteins, the level of TPI was negatively correlated with the post-thawed sperm progressive motility (r = -0.35, P = 0.05) and total motility (r = -0.43, P = 0.01). Additionally, the level of TPI was higher in moderate (4.4 ± 0.46, P < 0.05) than good (3.2 ± 0.36) and poor (4.1 ± 0.39) freezability ejaculates. The level of ACRBP did not differ significantly among semen freezability groups. However, the level of ACRBP was positively correlated with post-thawed total sperm motility (r = 0.38, P = 0.03). It could be concluded that boar semen containing a high level of FN1 in seminal plasma had a higher freezability than those containing low level of FN1. The post-thawed sperm motility were positively correlated with the level of FN1 in boar seminal plasma and the level of ACRBP in spermatozoa and negatively correlated with TPI in boar spermatozoa.
Optimization of d-lactic acid production by terrilactibacillus laevilacticus SK5-6 and fermentation process scale up in 30 litre-fermentor
Authors:   , Toliang Woraphot 
Published: September 2023

PLA, which is one of biodegradable plastic stereocomplex is made by block polymerization of optically pure L- and D-lactic acid. With stereoblock structure, heat and mechanical properties of PLA products can be improved. Thus, the demand of D-lactic acid has been increased. However, the market supply is still limited. In-house work reported that Terrilactibacillus laevilacticus SK5-6, the novel bacterium has been isolated from soil and later identified as the potent D-lactic acid producer. Moreover, it could produce high D-lactic acid from glucose with high optical purity in flask scale. To improve the fermentation performance, further process optimization was conducted in a 5 L stirred fermentor. The effects of inoculum size, seed age and volume of seed on D-lactic acid production were determined for establishing the platform. This work shows that the novel strain could produce high concentration of D-lactic acid with high yield and optical purity as well as the flask scale production. It was observed that 88.0 g/L of D-lactic acid with yield of 0.87 g/g glucose and productivity of 1.83 g/L/h were obtained with the mid log phase of 1% inoculum size and 10% seed transfer. Furthermore, the high optical purity of 99.3% could also be obtained from this isolate in the 5 L fermentor operation with above conditions. To develop the fermentative process scale up platform for D-lactic acid in the 30 L stirred fermentor. The seed train was developed for fermentation by used the conditions that had optimized in 5 L fermentor. In addition, the engineering parameters were tested as scale up factors by assuming constant mass transfer pattern in both scales. The results of testing scale up in 30 L fermentor show that T. laevilacticus SK5-6 could produce 81.5 g/L of D-lactic acid and productivity of 2.09 g/L/h, which was higher than 5 L scale slightly. They were obtained with 10% preculture seed transfer (seed in 250 mL flask) and using power input per volume (P/V) for agitation criteria. In addition, the high optical purity of 99.3% could also be obtained in the 30 L fermentor as well as production in 5 L scale. Therefore, the novel D-lactic acid producer, T. laevilacticus SK5-6 should be suggested as the potential strain for D-lactic acid production in the industrial scale.
Detection and distribution of Enterotoxin and Adhesin genes of Staphylococcus Pseudintermedius isolated from dog, human, and environment
Authors:   , Phumthanakorn Nathita 
Published: September 2023

To obtain the information of virulence factors associated with Staphylococcus pseudintermedius pathogenicity, host survival and adaptation, the study of staphylococcal enterotoxin (SE) genes and cell wall-associated (CWA) protein genes in S. pseudintermedius isolates from dogs, humans, and environment were performed. Human methicillin-resistant Staphylococcus pseudintermedius (MRSP) harbored the hightes number of SE genes at 12 out of 17 genes compared to those from dogs at 5 and environmental isolates at 3 gene types. For CWA protein genes or S. pseudintermedius surface proteins (sps), there was no an easy and fast method to detect them. Therefore, this study develop the multiplex PCR assays (mPCRs) for detection of 18 sps genes. spsP and spsQ were more frequently detected in the canine isolates from infected sites than from carriage sites with statistically significant. The positive amplicons of spsR gene in three human isolates showed partial gene deletions. Adherence assays were performed to assess the ability of 5 MRSP isolates from different origins and to find the relation with CWA protein gene profiles. Three MRSP-ST45 from dog, human, and environment had the greatest ability to adhere to both canine and human corneocytes without the association to sps gene profiles. This study successfully developed the novel mPCR for sps genes detection. The association between sources and enterotoxin genes were hightlighted in the isolates from humans. The diversity of virulence genes in human isolates are assumed to transfer by mobile genetic elements and might associate with higher pathogenicity than dog, and environmental isolates. Moreover, the diversity of sps may be responsible for host adaptation.
Dual infection between a Thai isolate highly pathogenic porcine reproductive and respiratory syndrome virus and pandemic H1N1swine influenza virus in weanling pigs
Authors:   , Sangpratum Nattaphong 
Published: September 2023

After an introduction of pandemic H1N1 swine influenza virus (pdmH1N1 SIV) in the Thai swine farms, mild clinical outcome is observed and its role in porcine respiratory disease complex (PRDC) is questionable. A highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) has become endemic in the Thai swine farms. This study was conducted to determine the pathogenicity of the pdmH1N1 SIV when co-infected with a HP-PRRSV. Thirty-two weanling pigs from a free PRRSV, SIV, porcine circovirus type 2 (PCV-2) and Mycoplasma spp. commercial farm were randomly divided into 4 groups: Negative, PRRSV, SIV and Co-infection groups. Pigs in PRRSV and Co-infection groups were challenged intranasally with the Thai isolate HP-PRRSV at 0 days post HP-PRRSV challenge (dphc) and pigs in SIV and Co-infection groups were inoculated intratracheally with pdmH1N1 SIV at 6 dphc. The 1st and 2nd necropsies were done at 2 and 4 days post SIV challenge (dsc). A comparison of the lung lesion scores between PRRSV and Co-infection groups at 2 dsc showed no statistical difference, but at 4 dsc, lung lesions score of the Co-infection group had higher average score than that of the PRRSV only group. Also, SIV viral load in the lung of the Co-infection group showed higher viral load at 4 dsc, comparing to the SIV-infected group significantly. The results suggest that the low pathogenic pdmH1N1 SIV could enhance the lung severity when co-infected with the HP-PRRSV possibly leading to porcine respiratory disease complex (PRDC).
Fatigue study of cancellous and cortical stainless steel screws used with polymethymethacrylate and the SOP plate system for the immobilisation of vertebral fracture and luxation in canine cadavers
Authors:   , Mekavichai Mingrath 
Published: September 2023

Globally, vertebral fracture and luxation (VFL) are one of the most common neurological injuries in dogs and cats. The standard care for vertebral body stabilisation of canine VFL are screws with polymethylmethacrylate (PMMA) and the string of pearls (SOP) plate system fixation. The VFL with implants are usually exposed to force in a repetitive or cyclic loading fashion. Indeed, stress on the implant cyclically at a load significantly less than its ultimate tensile strength can cause fatigue failure, one of the major causes of implant breakage. This study aims to compare the failure mode of four different implants using a specifically designed fatigue testing machine. The four different implants were constructed as follows: 3.5 mm cancellous screw with manually applied PMMA (MP), 3.5 mm cancellous screws with syringe application of PMMA (CanP), 3.5 mm cortical screws with syringe application of PMMA (CorP) and 3.5 mm cortical screws with a SOP plate (SOP). The results revealed that the SOP group tolerated the most cycles before failure, followed by the CorP, CanP and MP groups repectively. The point of weakness, as defined by the failure mode, occurred in the middle of the PMMA bridge, 3.5 mm cancellous screw neck, PMMA at the screw neck position and 3.5 mm cortical screw in MP, CanP, CorP and SOP groups respectively. In conclusion, based on fatigue properties of the four implants tested in this study, the SOP plate is recommended as a standard fixation device for VFL in dogs.