bluuebunny/crossref_metadata_2025_split huggingface dataset:
OBTAINING A MODIFYING ADDITIVE FOR BUILDING MIXTURES BASED ON SYNTHETIC FIBER PRODUCTION WASTE
Authors: YAKUBOUSKI S. , BULAUKA Y. , BAKATOVICH A. , ERMAK A. , AZARENKO D. 
Published: September 2023

An analysis was made of the possibility of using technical waste in the production of synthetic fiber Nitron-D
to obtain a modifying additive for building mixtures. An analysis was made of the possibility of using technical waste in
the production of synthetic fiber Nitron-D to obtain a modifying additive for building mixtures. A comprehensive analysis
of the effectiveness of a modifying additive for building mixtures based on waste from the production of synthetic
fibers makes it possible to predict an increase in the plasticity of the mixture and its corrosion resistance, a decrease in
W / C, an increase in the workability of building mixtures and a simplification of their surface machinability; increasing
the cohesiveness and non-separability of building mixtures at low cement consumption, as well as their high pumpability
with concrete pumps. Recycling of waste from the production of synthetic fiber will expand the range of products,
reduce the amount of waste to be disposed of and recycled, which, in turn, will reduce the negative burden on the environment
and will allow organizations to become resource-saving, low-waste and waste-free.
INVESTIGATION OF THE PHASE FORMATION PROCESS
DURING THE SYNTHESIS OF CERAMIC MATERIALS
BASED ON MODIFIED YTTRIUM MANGANITE
Authors: HUNDZILOVICH M. , POPOV R. , DYATLOVA E. , BUKA A. , MARINENKO A. 
Published: September 2023

The aim of this work is to establish the nature and sequence of phase formation processes in the synthesis of ceramic
materials based on yttrium manganite using different manganese oxides and structure modifiers. Differential scanning calorimetry,
X-ray phase analysis, and scanning electron microscopy were used as research methods in the work. The physicochemical
and electrophysical properties of the obtained samples were determined. Samples of modified yttrium manganite
were obtained by solid-phase sintering of the initial components at various temperature-time parameters of heat treatment.
The influence of Bi2O3, CoO and TeO2 additives on the physicochemical and electrophysical properties of prototypes was
studied. Regularities of the structure formation processes and phase composition of ceramic materials are established in
relation to the composition of raw materials and the technological parameters of the synthesis of modified yttrium manganite.
It has been established that the addition of oxides of the RO type contributes to a decrease in the degree of crystallization
of the samples, as evidenced by a decrease in the intensity of the diffraction peaks of the crystalline phases. In this case,
the qualitative composition of the phases practically does not change, but the proportion of the amorphous component in the
structure of the material increases. Bi2O3 has the most effective modifying effect in the synthesis of yttrium manganite.
Its addition into the composition of the raw mixture intensifies the process of formation of the yttrium manganite phase with
a crystal size of 2–4 μm, which is confirmed by the results of DSC, XRD, and electron microscopy. The intensification of the
crystallization process due to the addition of bismuth oxide is explained by the developed mechanism of liquid-phase sintering
and the formation of a significant number of crystallization centers. The developed ceramic materials based on modified
yttrium manganite have a set of electrophysical characteristics that make it possible to recommend them for the manufacture
of various elements of electronic technology.
Ailevi Akdeniz Ateşi Tanısı ile Takipli Hastalarda İlaç Uyumunun Hastalık Seyrine Etkisi
Authors: SÖNMEZ Hafize Emine , AKTAY AYAZ Nuray 
Published: September 2023

Giriş: Ailevi Akdeniz ateşi (AAA), yineleyen ateş ve seröz zarların non-enfeksiyöz enflamasyonu ile karakterize bir hastalıktır. Bu çalışmada AAA hastalarının ilaç uyumunu değerlendirmek ve tedavi uyumunun acil servise başvuru, hastane yatış sayısı, ek ilaç ihtiyacı, okul devamsızlığı ve ebeveynlerin iş devamsızlığına olan etkisinin belirlemesi amaçlanmıştır.
Yöntem: Kasım 2018-Ocak 2019 tarihleri arasında polikliniğe başvuran ve AAA tanısı ile takipli olan hastalar çalışmaya dâhil edildi. Hastalar ilaç uyum durumuna göre iki alt gruba ayrıldı (İlaç uyumu var/ilaç uyumu yok). İlaç uyumu AAA (MASIF) ilaç uyum ölçeği ile değerlendirildi.
Sonuç: Çalışmaya AAA tanısı ile takipli 82 hasta dâhil edildi. Bu hastalardan 49’unun ilaç uyumu tam iken 33 hastanın ilaçlarını düzgün kullanmadığı saptandı. Bu iki grup karşılaştırıldığında ilaç uyumu olmayan hastaların yaş ortalaması daha yüksekti ve bu hastalar daha yüksek dozda kolşisin kullanmaktaydı. İlaç uyumu olmayan hastalarda son altı aydaki atak, hastaneye başvuru, acil servise başvuru ve hastanede yatış sayısı anlamlı olarak fazlaydı. Atak nedeniyle okul devamsızlığının ilaç uyumu olmayan çocuklarda daha çok olduğu saptandı.
Tartışma: İlaç uyumunun olmaması hastaların uzun vadede daha çok doktora başvurusuna neden olmaktadır. Bu durum hem iş gücü kaybı hem de hasta başına düşen tedavi maliyetlerini artırmaktadır. Özellikle ergenlik döneminde ilaç uyumunu azaldığı göz önünde tutulduğunda kronik hastalığa sahip bireylerin ilaç uyumlarını artırmaya yönelik çalışmalar gerekmektedir.
Meme MRG’de Kitlesel Olmayan Kontrastlanma: Benign-Malign Patolojik Tanı ve Meme Kanserinde Moleküler Alt Grupların Dağılım ve Kontrastlanma Paternleri ile Karşılaştırılması
Authors: USLU Hande , TOSUN Mesude , ARSLAN Arzu Serpil 
Published: September 2023

Objective: The aim of our study is to investigate the distribution of lesions (focal, linear, segmental, regional, multiple regions, diffuse) and internal enhancement patterns (IEP) (homogeneous, heterogeneous, clumped, clustered ring) between benign and malignant type of NME and to evaluate the difference between Ki-67 and molecular subtypes (Luminal A, Luminal B, Basal-like, and HER2(+)) in malignant group.
Methods: A total of 923 women who underwent routine breast MRI between January 2015 and May 2018 were retrospectively reviewed. 88 MR images were included in the study. Histopathological results were 46 benign and 35 malignant lesions. We compared the distribution and IEPs between benign and malignant type of NME. In the malignant group, distribution and IEPs of different molecular subtypes and Ki-67 values were compared.
Results: Clustered ring internal enhancement were significantly associated with malignancy, while focal distribution and homogeneous enhancement pattern were associated with benignancy. A binomial logistic regression model explained 52.4% of the variance in benign-malignant status and correctly classified 77.3% of cases. Model sensitivity was 74.3%, specificity was 79.2%, positive predictive value was 70.2% and negative predictive value was 82.3%. There were not statistically significant differences in either distribution type of lesions or IEPs between molecular subtypes of malignant NME with different Ki-67 values.
Conclusion: 3-T MRI findings of focal distribution and homogeneous enhancement pattern were found to be a significant predictor of benign NME. Clustered ring enhancement can predict the probability of malignancy for non-mass like enhancement lesions.
Effect of Intravenous Lipid (SMOFLIPID®) Use along in Vitro Fertilization (IVF) Treatment in Women with Failed IVF Cycles Despite Good Quality Embryo Transfer
Authors: AKAR Bertan , DOĞAN Ozan , KÖLE Emre , ÇALIŞKAN Eray 
Published: September 2023

Objectives: Since recurrent implantation failure (RIF) is a challenging fact, effects of different therapeutic immunomodulatory agents are being investigated to overcome this problem. This study aimed to evaluate the effect of intralipid on pregnancy outcomes of IVF patients with RIF.
Methods: 116 of the participants who received only the short antagonist protocol allocated in the control group, whereas 106 patients were in intralipid group by additionally receiving intravenous lipid (SMOFlipid®). Intralipid was given on the day of embryo transfer, on the day of positive pregnancy test and continued weekly until the tenth week of pregnancy. Implantation rate, biochemical pregnancy rate, clinical pregnancy rate and live birth rate were evaluated.
Results: The positive pregnancy test, clinical pregnancy rate and live birth rate were statistically significantly higher (p0.05).
Conclusions: This study revealed that intralipid therapy has better pregnancy outcomes in patients with RIF compared to patients undergo standard IVF protocol only. Further prospective studies are needed to suggest the routine use of intralipid in patients with RIF.
Benzimidazole-thiazole hybrids; synthesis, structure elucidation and cytotoxic properties
Authors: COŞKUN Göknil , ERDOĞAN Ömer , CEVİK Ozge , ŞAHİN Zafer , DEMİRAYAK Şeref 
Published: September 2023

Aim: Neuroblastoma is one of the leading tumors among the childhood cancers and the treatment of the disease is currently being investigated. As the metastatic ability of the cells is high, current anticancer therapy needs improvement.
Method: Therefore, here five novel benzimidazole-thiazole compounds were synthesized. Their strucutres were elucidated using spectroscopic methods like FTIR, NMR and Mass analysis. The synthesis monitoring and purity of the compounds were performed with chromatographic methods. The compounds biological activity on SH-SY5Y neuroblastoma cell line was investigated using MTT assay.
Results: All of the tested compounds showed moderate cytotoxic activity. The best IC50 was obtained from compound 6b with the IC50 value of 175,02±4,17 µM.
Conclusion: These results indicated that benzimidazole-thiazole core is important for anti neuroblastoma activity, however, the ability of intramolecular hydrogen bonding could block the anticancer activity.
Electronic and topological investigation of antitubercular tryptanthrin analogues and their interaction with the enoyl-ACP reductase
Authors: AKSAKAL DAĞDELEN Fatma 
Published: September 2023

Objective:
This study aimed to investigate the structure-antitubercular activity relationships of a series of tryptanthrin analogues and the binding mechanisms of these analogues with InhA, Mycobacterium tuberculosis enoyl-acyl carrier protein (enoyl-ACP) reductase.
Methods:
Structure-activity relationships were investigated by using Electronic-Topological Method combined with Neural Networks (ETM-NN). Binding energies and non-covalent interactions stabilizing the ligand-InhA complex were obtained from the results of molecular docking. To assess these interactions, frontier molecular orbital analysis of the ligand-InhA complexes were also analysed.
Results:
The results of the ETM-NN application to the series of compounds in view are pharmacophoric and anti-pharmacophoric molecular fragments, which are characteristic of the class of compounds demonstrating activity against Mycobacterium tuberculosis strain H37Rv. The statistical characteristics of five pharmacophores (Phi) and five anti-pharmacophores (APhi) entering the forecasting system, are 0.90 and 0.86, correspondingly. Analysis of the electron density distribution has shown that the more effective binding with receptor was observed for active compounds.
Conclusions:
A system of prognosis for the anti-tubercular activity of Mycobacterium tuberculosis H37Rv was developed on the base of the pharmacophores found, docking results, and electronic structure calculations. This prognosis system allows for designing of new potent antitubercular drugs.
Keywords: Tryptanthrin analogues, mycobacterium tuberculosis H37Rv, InhA electronic-topological method, molecular docking, density functional theory
LÖSEMİ DIŞI ÇOCUKLUK ÇAĞI KANSERLERİNDE FEBRİL NÖTROPENİ ATAKLARININ DEĞERLENDİRİLMESİ
Authors: UÇAK Kübra , AZİZOĞLU Mehmet , DEMİRSOY Uğur , ÇORAPÇIOĞLU Funda 
Published: September 2023

Amaç: Çocukluk çağı solid tümörlerinde febril nötropeni ataklarının klinik seyir ve özelliklerini değerlendirerek uygun bir takip ve tedavi yaklaşımı oluşturmaktır.
Yöntemler: Çalışmamızda, Kasım 2019- Nisan 2020 tarihleri arasında kliniğimizde takip edilen lösemi dışı çocukluk çağı kanseri tanılı 18 yaş altı 30 hastanın 60 febril nötropeni atağı, tedavileri, tedavi yanıtları ve ailelerin sosyo-ekonomik düzeyleri incelendi.
Bulgular: En sık tanılar; nöroblastom (%31,7), Wilms tümörü (%16,7) ve non-Hodgkin lenfoma (%18,3) idi. Ataklar sırasında alınan kültürlerin 15’inde (%25) üreme saptandı. 10 atakta (%16,6) bakteriyemi mevcuttu. Febril atakların %76,7’sinin (46 atak) kemoterapi uygulamasından sonraki ilk 7 gün içinde meydana geldiği saptandı. En fazla atak görülen günler, kemoterapi uygulamasından sonraki 5. ve 6. (%33,4) günlerdi. Başvuru sırasında ateşi daha yüksek olan ve beyaz küre sayısı düşük hastaların ilerleyen süreçte tedavilerinde değişiklik yapılma ihtiyacının diğer hastalara göre daha yüksek olduğu saptandı. Üç hasta (%5) atak sırasında kaybedildi. Aylık geliri 4000 TL üzerinde ve eğitim düzeyi daha düşük olan ailelerin, hastaneye ulaşma sürelerinin anlamlı olarak daha kısa olduğu görüldü.
Sonuç: Febril nötropeni atakları sırasında ailelerin sosyo-kültürel ve ekonomi düzeyleri, iyileşme sürecini doğrudan etkileyebilmektedir.
Empagliflozine Bağlı Gelişen Öglisemik Diyabetik Ketoasidoz; Olgu Sunumu
Authors: KARABACAK Pınar , ÇELİK Süleyman , KÖSEM Ayşe , ÖZCAN Mustafa Soner , ÖZDEN Eyyüp Sabri 
Published: September 2023

Hiperglisemi (Kan şekeri> 250 mg/dL), metabolik asidoz (pH < 7,3), ketozis diyabetik ketoasidozun tanı kriterleri olarak belirtilmektedir. Nadiren kan şekeri 250 mg/dL altında diyabetik ketoasidoz görülebilmektedir. Bu durum öglisemik diyabetik ketoasidoz olarak adlandırılmaktadır. Nadir bir durum olmasına rağmen normal bir glukoz düzeyi tanıdan uzaklaştırabileceği için tedavinin gecikmesine ve bunun sonucunda artmış morbidite ve mortaliteye sebep olabilir. Sodyum-glukoz ko-transporter 2 (SGLT-2) inhibitörleri, diyabetes mellitus tedavisinde kullanılan yeni kuşak oral antidiyabetik ilaçlardır. Öglisemik diyabetik ketoasidoz gibi, nadir fakat ciddi advers etkileri vardır.
Bu olgu sunumunda, nadir görülen bir durum olan empagliflozin kullanımına bağlı gelişen öglisemik diyabetik ketoasidoz olgusunun sunulması amaçlanmıştır.
PROTECTİON FROM AEROSOLS DURİNG MICROSCOPIC MASTOİD SURGERY İN THE COVID-19 PANDEMİC
Authors: MUTLU Fatih , ERŞAHAN Ata Alperen , ÖZTÜRK Murat 
Published: September 2023

Purpose: To design a protective method from aerosols during mastoid surgery in COVID-19 pandemic. Material and
Material and Methods: We designed and applied a barrier tent from microscope to surgical field for four procedures of otologic surgeries
Results: There were neither symptoms nor signs of COVID-19 infection in the surgery team.
Conclusion: This protective method will provide a safe and comfortable way to perform microscopic mastoid surgery.
PRİMER UNİLATERAL OVERYAN KAPİLLER HEMANJİOM: OLGU SUNUMU
Authors: CİVRİZ Esra , VURAL Çiğdem , TURAN Gupse , CİVRİZ Aziz Hakkı 
Published: September 2023

ÖZ:

GİRİŞ
Primer hemanjiomlar, kadın genital traktında oldukça seyrek görülen, genellikle asemptomatik seyir
gösteren benign tümörlerdir.

OLGU SUNUMU
44 yaşında asemptomatik hastada, Ca125 düzeyinin yüksek gelmesi üzerine yapılan transvajinal ultrasonografisinde sağ overinde 68 mm boyutlarında düzensiz heterojen yapı ve douglas poşunda sıvı görülmüş ve sağ unilateral salpingooferektomi yapılmıştır. Morfolojik olarak; genel olarak küçük, bir kısmı küboidal ve basıklaşmış endotelyal hücreler ile döşeli prolifere vasküler yapılardan oluşan tümöral lezyon destekleyici immünhistokimyasal çalışmalar sonucunda “Overyan Kapiller Hemanjiom” tanısı almıştır.

TARTIŞMA
Biz burada; Ca 125 düzeyinin yüksekliği nedeniyle taranırken insidental olarak saptanan ve nadir bir antite olan overyan kapiller hemanjiom olgusunu sunup bu nadir tümörün histopatolojik özelliklerini ve ayırıcı tanısını literatür eşliğinde gözden geçirdik.
Rezension von: Lenz, Hermann, Im Hohenloher Land ...
Authors: Göpfert Eberhard , Lenz Hermann 
Published: September 2023

Hermann Lenz: Im Hohenloher Land. - Freiburg i. Br.: Eulen, 1989. - 48 S.: Ill.
Einladung, Hermann Lenz zu lesen / hrsg. von Rainer Moritz. - Frankfurt a. M.: Suhrkamp, 1988. - 208 S. (Suhrkamp Taschenbuch; 2099)
Rainer Moritz: Schreiben, wie man ist. Hermann Lenz: Grundlinien seines Werkes. - Tübingen: Niemeyer, 1989. - 350 S.
Rezension von: Hampele, Walter (Hrsg.), Gymnasium bei St. Michael Schwäbisch Hall ...
Authors: Akermann Manfred , Hampele Walter 
Published: September 2023

Gymnasium bei St. Michael Schwäbisch Hall. Geschichte und Geschichten / hrsg. von Walter Hampele i. A. des Freundeskreises alter Haller Pennäler Gymnasium bei St. Michael e. V. - Schwäbisch Hall: Mahl, 1990. - 127 S., Ill.
Schulleiterwechsel am 14. Juli 1990 Gymnasium bei St. Michael Schwäbisch Hall. - 68 S. (Synthesis 1990; Sonderh.)
Chitosan improves the efficacy of gentamicin against MDR and biofilm-forming URO pathogenic E. coli
Authors: Khan Fawad , Shah Didar Ali , Ahmad Syed Sohail , Fahimullah Fahimullah , Mazhar Mazhar , Khan Sumia , Mughal Haris Saleem , Khan Farhad , Bukhari Nain Taara 
Published: September 2023

Uropathogenic E. coli is the most common cause of urinary tract infections (UTIs), accounting for 80-90% of community-acquired UTIs and 30-50% of hospital-acquired UTIs. Uropathogenic E. coli that form biofilms are linked to chronic and persistent inflammation, resulting in severe and recurring UTIs. Biofilms promote antibiotic resistance and the horizontal transfer of virulence genes, promoting the formation of multidrug-resistant organisms. This study aimed to combine low-molecular-weight chitosan with aminoglycoside gentamicin to improve its efficacy against biofilm formation and MDR E. coli. Different strains of bacteria were isolated from urine samples of different patients at the Ayub Teaching Hospital, Abbottabad, out of which 16 were identified as E. coli by API (Analytical Profile Index) 20E. The antibiotic sensitivity profile was determined using the disk diffusion method, and the results showed that a total of 10 isolates were found to be multidrug-resistant MDR (N=62.5%). Biofilm formation was tested using the TCP method, a total of 7 isolates were found to be strong biofilm producers (N=44%). Gentamicin exhibited the highest inhibitory activity against 10 isolates of E.coli, with MIC-p ranges of 4 and 2 µg/ml, respectively, while 6 isolates showed resistance to gentamicin with MIC-p ranges >512 µg/ml.
Are Mega-Events Only for Global Cities? Analyzing Host Cities through the Global and World Cities Framework, 1990–2020
Authors: Faure Alexandre , Lauermann John 
Published: September 2023

Abstract
Mega-events have long been promoted as opportunities for cities to become more globalized, thereby enhancing tourism- and consumption-based economic development. But does this mega-event strategy actually work for smaller cities? This article compares the recent history of mega-event planning to cities’ ratings on the Global and World City (GaWC) ranking system, a typology for evaluating cities’ connectivity within the global economy. We surveyed 138 cities that bid on or hosted a variety of multi-sport mega-events. Competition for the most prominent mega-events is dominated by the most globalized “alpha” ranked cities, though less-globalized cities regularly bid for and host smaller mega-events. On average, hosting a mega-event has no significant effect on a city's GaWC ranking. Using a subsample of bids for the Summer Olympics, we further find that there is no specific model of mega-event planning in alpha cities: simply being a large and highly globalized city appears to be central to their success. This suggests mega-events are not a realistic mechanism for smaller and less-globalized cities to advance their global ambitions.
Sosialisasi Perhitungan PPh 21 Asyiknya Hitung PPh 21, Gampang dan Mudah Dipahami pada Karyawan PT Nano Herbaltama Internasional
Authors: Nurholis Nurholis , Misrudi Misrudi , Andini Andini , Lesmana Indra , Ariyanto Dedi 
Published: September 2023

Pengabdian ini berjudul asyiknya hitung PPh 21, gampang dan mudah dipahami yang berdampak pada pengetahuan perpajakan karyawan PT Nano Herbaltama Internasional. Tujuan umum dari kegiatan pengabdian kepada masyarakat ini adalah Memberikan pelatihan dan pengetahuan secara praktis ilmu pajak tentang perhitungan PPh 21. Metode yang digunakan adalah metode presentasi dan penyampaian materi secara langsung serta simulasi dan diskusi mengenai perhitungan PPh 21. Kesimpulan dari pengabdian kepada masyakat ini adalah bahwa akan dilakukan presentasi mengenai perhitungan PPh 21 orang pribadi serta penjelasan tarif terbaru yang digunakan dalam perhitungan, penyampaian materi dalam upaya mewujudkan peningkatan pengetahuan perpajakan karyawan.
Evaluation of the implementation of the reaching every district approach in routine immunisation in Lusaka District, Zambia
Authors: Mwanamwenge A , Masumbu P , Mwansa FD , Masaninga F , Mazaba ML , Songolo P , Kachimba JS , Vwalika B , Mufunda J 
Published: September 2023

Background: In 2003, the Government of Zambia in collaboration with implementing partners in immunisation introduced the Reaching Every District (RED) strategy to improve immunization coverage. The aim of this study is to evaluate the implementation of the RED strategy in Lusaka district.
Methods: A questionnaire was administered among health centres in charge of all governmental health clinics in Lusaka districts (N = 27). RED implementation was quantified by calculating a RED implementation score (IS) for each of the RED components on a scale of 0 (low implementation score) to 5 (high implementation score).
Results: The mean overall RED implementation score was 3.5. The RED component of linking services with community and re-establishing outreach were the two weakest components.
Conclusions and recommendations: This evaluation showed that there are a number of elements of the RED strategy which are well implemented; however, some elements need further improvements. There is need for more research on the implementation of the RED strategy in Zambia in order to identify bottlenecks for improving immunization coverage at larger scale and a wider participation.
GINKGO BILOBANING FLAVONOID TARKIBI
Authors: Asqarov Ibrohimjon Rahmonovich , Razzaqov Nabijon Alijonovich 
Published: September 2023

Serquyosh O‘zbekiston sharoitiga iqlimlashtirilgan Ginkgo biloba o‘simlikning flavonoid tarkibini YUSSX yordamida o‘rganildi. Markaziy asab tizimida kuzatiladigan gipoksiya ( kislorodning tanqisligi) holatlarida miya kapilyarlarining o‘tkazuvchanligini yaxshilash orqali nerv to‘qimalarini kislorod bilan ta’minlash haqida so‘z boradi. Ensefalopatiyani oldini olishda ginkgo biloba o‘simligi tarkibidagi biologik faol flavonoidlarning ta’siri keltirilgan.
Vleermuizen en de vrienden van de rechter
Authors: van der Veen G.A. (Gerrit) 
Published: September 2023

Vleermuizen en de vrienden van de rechter
In dit redactioneel wordt ingegaan op de eerste uitspraak van de Afdeling bestuursrechtspraak van de Raad van State met toepassing van de amicus curiae-regeling. Het betreft de uitspraak omtrent het na-isoleren van spouwmuren en nadelige effecten voor beschermde vleermuizen.