bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of exercise therapy, systemic acupuncture and silicon oxide tablets on muscular strength, lymphedema, and quality of life in breast cancer survivors: randomized clinical trial
Authors: Giron Patricia Santolia , Haddad Cinira Assad Simão , Rizzi Samantha Karla Lopes de Almeida , Elias Simone , Nazário Afonso Celso Pinto , Facina Gil 
Published: July 2023

Abstract
Purpose: To compare three distinct rehabilitation treatments (exercise therapy, acupuncture, and silicon oxide tablets (Stiper®) in women undergoing breast cancer surgery, assessing strength, lymphedema, and quality of life.
Methods: Seventy-nine women with pain above 3 on the visual analogue pain scale (VAS) and with more than 90 days of surgery. Group I was treated with exercise therapy with a duration of 30 minutes, group II treated with 30 minutes of acupuncture using predefined points and group III treated with the same acupuncture points as group II, however, using the silicon oxide in place of needles.
Results: There was an improvement in upper limb muscle strength over time in all groups, except for abduction and internal rotation movements. During treatment, there was no increase in the number of patients with lymphedema and there was no statistical difference between the groups. Regarding the EORTC QLQ-C30 quality of life questionnaire, nine of the fifteen factors analyzed showed significant differences between sessions. The factors that did not have significant differences between the three groups were Social Function, Nausea and Vomiting, Dyspnea, Loss of Appetite, Constipation, and Diarrhea.
Conclusion:The rehabilitation of physical dysfunctions in women who survived breast cancer through exercise therapy, acupuncture, and silicon oxide tablets in upper limb muscle strength, lymphedema, and quality of life, proved to be effective, without difference between groups.
Clinical Trials registry on 01/11/2016, with number NCT02798263.
Generation of a C57Bl/6J mouse strain expressing the CD45.1 epitope to improve HSC engraftment and adoptive cell transfer experiments
Authors: Marvel Jacqueline , Laubreton Daphne , Djebali Sophia , Angleraux Céline , Chain Benny , Dubois Maxence , Henry Farida , Leverrier Yann , Teixeira Marie , Markossian Suzy 
Published: July 2023

Abstract
Adoptive cell transfer between genetically identical hosts is a key tool in the study of the murine immune system. In most models, host and donor differ by a congenic marker, i.e. alleles of a gene coding for a surface protein expressed by immune cells and which allows to trace the donor cells using an epitope specific antibody (Ab). CD45, a glycoprotein expressed by all hematopoietic cells and encoded by the Ptprc gene, constitute one of the main congenic markers used. Its two isoforms, CD45.1 and CD45.2, can be discriminated by flow cytometry using the anti-CD45.1 (clone A20) and anti-CD45.2 (clone 104) Ab. As a consequence, C57BL/6J (B6; CD45.2) and B6.SJL-Ptprca Pepcb/BoyJ (B6.SJL; CD45.1) mice are widely used in adoptive cell transfer experiments, under the presumption that they differ only at the CD45 (Ptprc) locus. However, the B6.SJL congenic mouse was generated by crossing an SJL mouse with a B6 mouse, followed by serial back-crossing on B6 mice with the selection of CD45.1 expressing animals at each generation. Recent studies identified genetic variations between these congenic strains and highlighted, among other, a differential expression of cathepsin E (CTSE). B6.SJL mouse presents a number of functional differences in hematopoietic stem cell (HSC) engraftment-potential or immune cell numbers. We show that B6 and B6.SJL mice also differ in their CD8 T cells compartment and CD8 T cells responses to viral infection compared to B6 mouse. We identified Ctse as the most differentially expressed gene between CD8 T cells of B6 and B6.SJL demonstrate that the differences reported between these two mouse strains are not due to CTSE.
In order to avoid biases associated with known or unknown polymorphisms found in congenic mice, we used CRISPR/Cas9 genome editing to introduce, in the Ptprc gene of B6 mouse (CD45.2 epitope), the point mutation(s) associated with its transformation into the CD45.1 epitope. We show that only one nucleotide mutation (A904G) leading to an amino acid change (K302E) is sufficient for the protein to be recognized by the anti-CD45.1 Ab.
We show that this new B6-Ptprcem(K302E)Jmar/J mouse has similar immune compartment compared to B6 mouse and does not show any difference in HSC engraftment or CD8 antiviral responses.
This new strain resolves the experimental biases reported between B6 and B6.SJL mouse lines and should thus represent the new gold standard for adoptive transfer experiments in B6.
Shedding light on the environmental impact of the decomposition of perovskite solar cell
Authors: Shahroosvand Hashem , Sabahi Negin 
Published: July 2023

Abstract
Perovskite materials, as the heart of perovskite solar cells, attracted great interest in the photovoltaic community since the efficiency of perovskite solar cells (PSC) dramatically increased to over 25%. However, the presence of Pb metal in the perovskite crystalline limits the progress of this new generation of solar cells from environmental aspects. Here, we have systematically investigated the impact of the decomposition of perovskite material on the a special plant, named Coleus. We found that the influence of the decomposition of a perovskite solar cell ( namely p-PbI2) has a three-fold lower destroying than commercial PbI2 which named s-PbI2 on the Coleus pant in the same condition. In particular, the p-PbI2 influenced on the roots and leaf slower and smoother than s-PbI2. Remarkably, the amount of water absorption with the plant′s root from p-PbI2 is two- fold lower than s-PbI2, indicating that s-PbI2 dramatically wasted water from roots and showing the most harmfulity. In following, the atomic absorption spectroscopy (AAS) was measured the lead concentration of the Coleus plants ashe which indicated that the amount of Pb in first week was estimated about 3.2 and 2.1 ppm for synthetic PbI2 (s-PbI2), and decomposed perovskite (p-PbI2), respectively, which for two next weeks the amount of Pb were calculated about relatively close together and finally in the last week decreased to 1.8 ppm for s-PbI2 and increased to 2.4 ppm for p-PbI2. Therefore, we conclude that the Coleus plant absorbed more Pb metal from s-PbI2 than p-PbI2 of a PSC, which is in contrast with recent report in Nature Communication′s paper, as will explain in the following sections. This paper opens new avenues and challenges about the actual scenario on the impact of perovskite materials in PSCs on the plant and live metabolisms.
Assessment of Corporate Social Responsibility Measures in Energy Sector
Authors: Kasradze Mariam , Streimikiene Dalia , Lauzadyte-Tutliene Agne 
Published: July 2023

Abstract
Energy companies are in the spotlight regarding the environmental pressure to address current environmental issues by initiating sets of social responsibilities. Energy sector companies are actively adopting Corporate Social Responsibility (CSR) practices to address the increased pressure and enablement to manage and prevent risks of environmental impact together with concentrating on economic growth. Current study provides a systematic literature review identifying CSR initiative measures toward sustainability and proposes a framework of CSR measurements in the energy sector. The framework combines the Search, Appraisal, Synthesis, and Analysis (SALSA) method together with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and PSALSAR (Protocol, Search, Appraisal, Synthesis, Analysis and Report). Moreover, for setting the research scope PICOC (Population, Intervention, Comparison, Outcome, and Context) is applied. As a result, eleven CSR measures for the energy sector were identified: environmental impact, reduction of GHG emissions, green energy innovations, CSR reporting, competitiveness, stakeholder engagements, branding and reputation, financial performance, the price for green energy, employees' safety and business strategy and corporate culture. The measurements were classified into 4 pillars: Environmental pillar, stakeholder communication and external image, financial pillar, and organizational pillar. Furthermore, research results were discussed and a future research agenda together with policy recommendations were provided.
Application of metagenomic next-generation sequencing in the diagnosis of Bartonella neuroretinitis: A case report and literature review
Authors: Li Pengcheng , Qian Zhuyun , Tao Yong 
Published: July 2023

Abstract
Background: Cat-scratch disease (CSD) is caused by Bartonella henselae infection. In atypical cases of CSD, pathogen determination is challenging. We report a case of Bartonella neuroretinitis with neither a clear history of scratches nor typical general symptoms. The diagnosis was made using metagenomic next-generation sequencing (mNGS), a high-throughput sequencing technology.
Case presentation: A female patient presented to the ophthalmologist with complaint of blurred vision in her right eye. Although with history of raising a cat, she reported no clear history of scratches or typical general symptoms, except a fever of unknown origin which resolved spontaneously. The best corrected visual acuity (BCVA) of the right eye was count fingers. Fundus examination showed optic disc oedema, macular exudates and inferior exudative retinal detachment. Laboratory examination results showed increased value of serum C-reactive protein and erythrocyte sedimentation rate. Ocular involvement of toxoplasmosis, syphilis and tuberculosis were excluded. To identify the possible causative pathogen of the disease, mNGS of aqueous humour sample was performed and 521 reads of B. henselae were identified. Serological test results further showed a positive immunoglobulin G (IgG) titre of 1:64. Taking the contact history, clinical manifestations, mNGS and serological results into consideration, the diagnosis of Bartonellaneuroretinitis (ocular CSD) was made. After appropriate treatment, the BCVA of the right eye improved to 20/25 in the last follow-up. Fundus examination showed a normal optic disc and macula, and the exudates had reduced.
Conclusions:mNGS, a fast and unbiased method, can be used to detect B. henselae (if present) in intraocular fluid samples.; however, the results should be interpreted together with the clinical symptoms and other auxiliary test results.
Delayed Naegleria fowleri diagnosis mimicking macrophage in a patient with seawater swimming
Authors: wang feng , shen fuping , zhao jiwei , chen xiaojuan , liu jinlin 
Published: July 2023

Abstract
This case report describes a 62-year-old male fisherman who presented with persistent vomiting, headache, and behavior changes. Despite initial antibiotic and corticosteroid treatment, his condition worsened, leading to coma and subsequent death. Postmortem macro-genome sequencing of cerebrospinal fluid (CSF) revealed the presence of Naegleria fowleri infection, which had been missed during initial laboratory tests. The patient's exposure history included sea-swimming near Zhoushan island.
Changes in the prevalence of obesity in Czech adolescents between 2018 and 2022 and its non-genetic correlates – HBSC study
Authors: Sigmund Erik , Sigmundová Dagmar , Pavelka Jan , Kalman Michal , Voráčová Jaroslava , Meier Zdeněk , Kopčáková Jaroslava , Badura Petr 
Published: July 2023

Abstract
Background: The main aim of the study is to examine changes in the prevalence of obesity in Czech adolescents between 2018 and 2022 and its non-genetic correlates with respect to the socioeconomic status (SES) of the c in 2022.
Methods: The sample of 24,535 adolescents (n=11,629/12,9062018/2022; boys: 50.4/50.6%2018/2022) aged 10.5-16.5 years that was analysed was drawn from two nationally representative cohorts of Czech youngsters from the last two cycles of the Health Behaviour in School-aged Children (HBSC) online questionnaire survey from 2018 and 2022. Obesity is represented by the >97th percentile interval on the World Health Organization Body Mass Index percentile chart, with distinctions by sex and the age of adolescents. The differences in the prevalence of obesity between boys and girls from all SES family categories in 2018 and 2022 were tested using a chi-square test (χ2). Multiple logistic regression analysis with repeated measures was used to analyse correlates of obesity in 2022.
Results: Between 2018 and 2022, there was no significant difference in the prevalence of obesity in girls or boys in any of the SES categories of families. Adolescents from low-SES families have the highest prevalence of obesity, 11% for boys and 5.8% for girls, significantly higher (p<0.001) than its prevalence among adolescents from high-SES families, by +4.8 percentage points for boys and +3.9 percentage points for girls. Among adolescents from low-SES families, individuals who engaged in moderate-to-vigorous physical activity (PA) daily (p<0.005) or vigorous PA three times per week (p<0.05) were significantly less likely to be obese than their less active peers. Skipping breakfast significantly (p<0.05) increased the odds of obesity, but only among adolescents from low-SES families. Shorter screen time (ST) significantly (p<0.05) reduced the odds of obesity for all categories of adolescent SES.
Conclusions: Obesity is most pronounced in adolescents from low-SES families as a result of a long-term positive energy balance mediated by unbalanced behaviour. Significantly lower odds of obesity in adolescents from low-SES families were confirmed to be associated with regular practice of the recommended PA, shorter ST, and not skipping breakfast.
Relationship between caesarean delivery and weight status in early childhood: a birth cohort study in Japan
Authors: Miyayama Chiharu , Morisaki Naho , Ogawa Kohei , Tanaka Hisako , Shoji Hiromichi , Shimizu Toshiaki , Sago Haruhiko , Horikawa Reiko , Urayama Kevin 
Published: July 2023

Abstract
To examine whether the prevailing hypothesis of an association between caesarean section (CS) delivery method and increased weight status in early childhood is observed in Japanese. A total of 1,277 mother-infant pairs from a prospective hospital-based mother-infant birth cohort that recruited women in their first trimester from May 2010 to November 2013 were included. We assessed the relationship between delivery method and weight status of delivered children at 1, 3 and 6 years of age. In total, 366 children (28.7%) were delivered by CS. Delivery by CS was not associated with body mass index (BMI) z-score (≥ 75 percentile) at age 1 year, (odds ratio (OR) 0.97, 95% confidence interval (CI) 0.69–1.36), 3 years (OR 0.98, 95% CI 0.67–1.42), and 6 years (OR 0.71, 95% CI 0.45–1.12), and also showed no association with low weight status (< 25th percentile). Supplemental evaluations addressing the influence of preterm births, pre-pregnancy BMI, emergency CS, and modification by breastfeeding were consistent with the primary analyses. Our findings do not support the hypothesis that children born by CS are at risk of being overweight in childhood among the Japanese population.
A Soybean bZIP transcription factor GmbZIP71-4 Is Involved in Submergence Resistance in Transgenic Tobacco
Authors: Lin Yanhui , Xia Changjian , Huo Xing , Xu Jing , Li Yapeng , Zhu Honglin , Tang Liqiong , Chen Dexin , Wang Xiaoning 
Published: July 2023

Abstract
Background
Although the role of the basic leucine zipper (bZIP) family of transcription factors in response to various abiotic stresses has been investigated, few studies have been conducted on their function in submergence stress.
Results
In this study, we localized a bZIP gene GmbZIP71-4 in the nucleus of soybean and constructed a GmbZIP71-4overexpressing tabocco line, which showed reduced submergence resistance due to the decreased abscisic acid (ABA) content. GO and KEGG pathway enrichment analysis based on chromatin immunoprecipitation assay sequencing (ChIP-seq) indicated that the most significant differences were the expression levels of the factors in plant hormone signal transduction, especially those in response to ABA. Electrophoretic Mobility Shift Assays (EMSA) demonstrated that GmbZIP71-4 bound to the promoter of GmABF2, which is consistent with the ChIP-qPCR result.
Conclusions
Our study showed that GmbZIP71-4 was a negative regulator of submergence stress tolerance. The findings in this work will set a solid foundation for the understanding of submergence resistance in plants.
The Paradoxical Impact of Diabetes Mellitus on Osteoporosis and Sarcopenia:
The ParaDOS Study
Authors: Tiftik Tülay , Kara Murat , Mülkoğlu Cevriye , Çiftçi İrem , Çiftçi Ömer Faruk , Durmuş Mahmut Esad , Kara Özgür , Kuşkonmaz Şerife Mehlika , Genç Hakan , Kaymak Bayram , Özçakar Levent 
Published: July 2023

Abstract
Purpose
Type 2 diabetes mellitus (T2DM), osteoporosis (OP) and sarcopenia are major public health problems related with higher fall/fracture risks, morbidity and mortality. Due to the lack of a comprehensive analysis among T2DM, OP and sarcopenia; we aimed to explore the impact of T2DM on OP and sarcopenia in postmenopausal women.
Methods
This cross-sectional study included postmenopausal women who admitted to the departments of physical & rehabilitation medicine, and endocrinology and metabolism. Demographic data, nutrition/cognition status and frailty scores were recorded. Sarcopenia-related parameters including SARC-F, anterior thigh muscle thickness, handgrip strength, chair stand test, gait speed, and one-leg stand test for balance were measured. ISarcoPRM algorithm was used for the diagnosis of sarcopenia.
Results
A total of 444 postmenopausal women were consecutively enrolled. T2DM patients (N = 158, 35.6%) had higher frequency of sarcopenia, but lower frequency of OP than controls (both p < 0.05). As regards regression analyses; T2DM - either under the treatment of oral antidiabetic drugs or insulin - had a negative association with presence of OP (about 2 to 3 times lower, respectively). The duration of T2DM had a positive association with sarcopenia and a negative association with balance (all p < 0.05).
Conclusion
T2DM has paradoxical effects on bone, muscle and balance. Although insulin treatment might have anabolic effects on bone (protecting OP), the disease (duration) itself has negative effects on sarcopenia/balance.
Effect of acute exercise on cfDNA levels considering menstrual cycle phases
Authors: Sawai Akemi , Shida Takashi , Hoshikawa Yoshihiro , Ueda Mashiro , Kato Yuri , Tokinoya Katsuyuki , Natsui Hiroaki , Kawakami Yasushi , Takekoshi Kazuhiro 
Published: July 2023

Abstract
This study aimed to determine the effects of exercise on cfDNA levels and concentration changes during the menstrual cycle in normal menstrual cycle participants with no exercise habits. Eleven females with normal menstrual cycles and ovulation performed bicycle exercises at 60% VO2max for 30 min during the menstrual, ovulatory, and luteal phases. Blood samples were collected before (Pre), immediately after (Post 0), 30 min after (Post 30), and 60 min after (Post 60) exercise, and blood concentrations of cfDNA, PGF2α, IL-6, and aromatase were evaluated. Serum estradiol levels were significantly higher in the luteal than those in the menstrual phase, whereas serum progesterone levels were significantly higher in the luteal than those in the menstrual and ovulatory phases. Estradiol levels increased significantly from Pre to Post 0 in the ovulatory and luteal phases, whereas progesterone levels increased in the luteal phase. cfDNA and aromatase concentrations significantly increased from Pre to Post 0 in all phases, but no significant phase differences were observed Pre or Post 0. Progesterone to estradiol level ratio (P4/E2) changes from Pre to Post 0 during the luteal phase were significantly negatively correlated (r = -0.82) to changes in cfDNA from Pre to Post 0.
A Mixed-methods Study of Adaption Challenges and Social Networks of Older Migrants in China
Authors: Wangliu Yiqi , Guo Jing , Hu Yang , Liu Yu 
Published: July 2023

Abstract
Background
Among the growing migrant population in China, older adults who choose to migrate with their children to provide caregiving for grandchildren have attracted scholarly attention. This study explored what challenges they have experienced in sociocultural and psychological adaptation process in host cities and what social support was effective based on the adaptation theory and stress and coping theory.
Methods
The study employed a mixed-method study. Twenty-five older migrants participated in interviews and 376 older migrants completed a set of surveys. Interview responses were analysed with the thematic analysis approach and quantitative data were examined with linear regression analyses.
Results
In the qualitative phase, interviews indicated that older migrants depended on not only social support from host cities, but also support from their hometown to deal with adaptation difficulties, so whether and how these types of support predicted different dimensions of adaptation was examined later through a questionnaire. In the quantitative phase, results of a survey showed that support from co-living children and new friends in the host city was the most effective protective factor to promote both sociocultural and psychological adaptation. Support from community services was positively associated only with sociocultural adaptation, while remote support from family and friends in their hometown was positively associated only with psychological adaptation.
Conclusion
These findings provide a better understanding of how older migrants experienced new lives in host cities, and they could guide professionals to provide older adults with necessary support and promote older adults’ adaptation to the current community.
Exploring the mechanism of grey forecasting models: A perspective from dynamic system modelling
Authors: Wang Xiaolei , Xie Naiming 
Published: July 2023

Abstract
The grey forecasting model has been developed for forty years, but there are various understandings of its modelling ideas. The research motivation of this paper is to provide an insight into the understanding of grey forecasting models and demonstrate how grey forecasting model can solve practical problems. Based on the modelling process of grey forecasting models, this paper first discusses the model mechanism from the perspective of dynamic system modelling and describes the model application using perishable products inventory as an example. Then, we introduced the modelling processes and characteristics of grey forecasting models under traditional and direct methods. The research issue of grey forecasting models is summarized by analysing model characteristics, the complete process of model establishment is presented, and the mechanism of each modelling process is elaborated in detail. Next, taking the inventory of perishable products as an example, we discuss how the grey forecasting model solves practical problems, and illustrate the application process of the grey forecasting model through a numerical example of citrus.