bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cyclin A participates in the TSO1-MYB3R1 regulatory module to maintain shoot meristem size and fertility in Arabidopsis
Authors: Wang Fuxi , Wang Wanpeng , Liu Zhongchi 
Published: February 2023

ABSTRACT
The stem cell pools at the shoot apex and root tip give rise to all the above- and below-ground tissues of a plant. Previous studies in Arabidopsis identified a TSO1-MYB3R1 transcriptional module that controls the number and size of the stem cell pools at the shoot apex and root tip. As TSO1 and MYB3R1 are homologous to components of an animal cell cycle regulatory complex, DREAM, Arabidopsis mutants of TSO1 and MYB3R1 provide valuable tools for investigations into the link between cell cycle regulation and stem cell maintenance in plants. In this study, an Arabidopsis cyclin A gene, CYCA3;4, was identified as a member of the TSO1-MYB3R1 regulatory module and cyca3;4 mutations suppressed the tso1-1 mutant phenotype specifically in the shoot. The work reveals how the TSO1-MYB3R1 module is integrated with the cell cycle machinery to control cell division at the shoot meristem.
Drosophilaembryos spatially sort their nutrient stores to facilitate their utilization
Authors: Kilwein Marcus D. , Johnson Matthew R. , Thomalla Jonathon M. , Mahowald Anthony P. , Welte Michael A. 
Published: February 2023

ABSTRACTAnimal embryos are provided by their mothers with a diverse nutrient supply that is crucial for development. In Drosophila, the three most abundant nutrients (triglycerides, proteins and glycogen) are sequestered in distinct storage structures: lipid droplets (LDs), yolk vesicles (YVs) and glycogen granules (GGs). Using transmission electron microscopy as well as live and fixed sample fluorescence imaging, we find that all three storage structures are dispersed throughout the egg but are then spatially allocated to distinct tissues by gastrulation: LDs largely to the peripheral epithelium, YVs and GGs to the central yolk cell. To confound the embryo's ability to sort its nutrients, we employ Jabba and mauve mutants to generate LD-GG and LD-YV compound structures. In these mutants, LDs are mis-sorted to the yolk cell and their turnover is delayed. Our observations demonstrate dramatic spatial nutrient sorting in early embryos and provide the first evidence for its functional importance.
GAF-RCNN: Grid attention fusion 3D object detection from point cloud
Authors: Li Zheng , Tong Guofeng , Peng Hao , Ma Mingwei 
Published: February 2023

Background: Due to the refinement of region of the interests (RoIs), two-stage 3D detection algorithms can usually obtain better performance compared with most single-stage detectors. However, most two-stage methods adopt feature connection, to aggregate the grid point features using multi-scale RoI pooling in the second stage. This connection mode does not consider the correlation between multi-scale grid features. Methods: In the first stage, we employ 3D sparse convolution and 2D convolution to fully extract rich semantic features. Then, a small number of coarse RoIs are predicted based region proposal network (RPN) on generated bird’s eye view (BEV) map. After that, we adopt voxel RoI-pooling strategy to aggregate the neighborhood nonempty voxel features of each grid point in RoI in the last two layers of 3D sparse convolution. In this way, we obtain two aggregated features from 3D sparse voxel space for each grid point. Next, we design an attention feature fusion module. This module includes a local and a global attention layer, which can fully integrate the grid point features from different voxel layers. Results: We carry out relevant experiments on the Karlsruhe Institute of Technology and Toyota Technological Institute (KITTI) dataset. The average precisions of our proposed method are 88.21%, 81.51%, 77.07% on three difficulty levels (easy, moderate, and hard, respectively) for 3D detection, and 92.30%, 90.19%, 86.00% on three difficulty levels (easy, moderate, and hard, respectively) for BEV detection. Conclusions: In this paper, we propose a novel two-stage 3D detection algorithm named Grid Attention Fusion Region-based Convolutional Neural Network (GAF-RCNN) from point cloud. Because we integrate multi-scale RoI grid features with attention mechanism in the refinement stage, different multi-scale features can be better correlated, achieving a competitive level compared with other well tested detection algorithms. This 3D object detection has important implications for robot and cobot technology.
“« Coffee agroforestry business-driven clusters »: an innovative social and environmental organisational model for coffee farm renovation
Authors: Meter Andrew , Penot Eric , Vaast Philippe , Etienne Hervé , Ponçon Eric , Bertrand Benoit 
Published: February 2023

Background: Worldwide coffee production, especially Arabica coffee, is threatened by climatic change, plants diseases and vulnerability of smallholders. Meanwhile, consumers’ demand for socially and environmentally sustainable products is steadily increasing, driving the engagement of stakeholders in agro-ecological and social initiatives. Here we present a new organizational model, the “Coffee agroforestry business-driven cluster” (CaFC), which aims at preserving ecosystems while offering producers a fair income. Based on an original local micro value-chain dedicated to sustainable production of high-quality Arabica coffee under agroforestry systems, the CaFC model stands out by addressing the issues around plantation renovation, a crucial process that requires considerable investments from producers. Methods: Based on a pilot project in Nicaragua, we illustrate how the operational principles of CaFC can be applied in a real setting. Using data shared by key stakeholders involved in the project, we assess the profitability of the CaFC model by comparing different scenarios and applying sensitivity analysis. We then reflect on the reproducibility of the model in other contexts, building on lessons learned from ongoing implementations in Vietnam and Cameroon. Results: For producers renovating their plantations, the CaFC model consistently outperforms other scenarios, offering high quality premiums coupled with capacity building, access to highly productive varieties that perform well under agroforestry systems and adapted credit with favourable repayment schemes. Implementation in Vietnam and Cameroon show that the model can be successfully replicated with some adaptation to local contexts. These cases also highlight the importance of mutual interests, trust and communication in enabling collaboration between stakeholders. Conclusions: The CaFC model has great potential for positive environmental and economic impact and offers strong incentives for stakeholders involved in its resulting micro value-chain. The concept was initially developed in Nicaragua for coffee but could also be adapted in other countries or even to other commodities such as cocoa.
Investigating the effect of cardio-visual synchrony on prosocial behavior towards a social robot
Authors: Riddoch Katie A. , Cross Emily S. 
Published: February 2023

Background: Robots are being designed to alleviate the burden of social isolation and loneliness, particularly among older adults for whom these issues are more widespread. While good intentions underpin these developments, the reality is that many of these robots are abandoned within a short period of time. To encourage the longer-term use and utility of such robots, researchers are exploring ways to increase robot likeability and facilitate attachment. Results from experimental psychology suggest that interpersonal synchrony (the overlap of movement/sensation between two agents) increases the extent to which people like one another. Methods: To investigate the possibility that synchrony could facilitate people’s liking towards a robot, we undertook a between-subjects experiment in which participants interacted with a robot programmed to illuminate at the same rate, or 20% slower, than their heart rate. To quantify the impact of cardio-visual synchrony on prosocial attitudes and behaviors toward this robot, participants completed self-report questionnaires, a gaze-cueing task, and were asked to strike the robot with a mallet. Results: Contrary to pre-registered hypotheses, results revealed no differences in self-reported liking of the robot, gaze cueing effects, or the extent to which participants hesitated to hit the robot between the synchronous and asynchronous groups. Conclusions: The quantitative data described above, as well as qualitative data collected in semi-structured interviews, provided rich insights into people’s behaviours and thoughts when socially engaging with a humanoid social robot, and call into question the use of the broad “Likeability” measurement, and the appropriateness of the ‘hesitance to hit’ paradigm as a measure of attachment to a robotic system.
Effects of nebulised beta-2 agonists on clinical observations in asthma exacerbations
Authors: Mortimer Craig , Nikoletou Dimitra , Ooms Ann , Williams Julia 
Published: February 2023

Background: Despite concerns over their side effects, short-acting beta-2 agonists are still used in high doses in prehospital care internationally to treat asthma exacerbations. This systematic review set out to identify the physiological effects associated with this treatment and determine their potential impact on the patient's presenting or underlying conditions. Methods: A systematic search of literature published from 2010 to 2020 focusing on asthmatic patients receiving nebulised beta-2 agonists during an acute exacerbation was undertaken and relevant articles reviewed. Findings: Eight out of 897 studies met the inclusion criteria. While the studies were heterogeneous with a range of outcome measures, synthesis showed evidence of bronchodilator action throughout, with reductions in potassium levels and cardiovascular changes reported in several studies. Conclusions: Therapeutic effects demonstrated within the data support the use of nebulised beta-2 agonists in these patients and, while adverse effects are frequently seen in the cardiovascular and endocrine systems, their impact on the patient's overall condition remains unclear.
Synthesis and nonlinear optical properties of polyurethane composites containing a pyrene derivative
Authors: Gao Lijun , Li Liuyang , Li Bin , Yi Haoyue , Zhou Liming , Qu Xiongwei , Fang Shaoming 
Published: February 2023

The pyrene derivative (PD) was synthesized with pyrene-1-carboxaldehyde and p-aminoazobenzene by a Schiff base reaction. Then the obtained PD was dispersed in polyurethane (PU) prepolymer to prepare polyurethane/pyrene derivative PU/PD materials with good transmittance. The nonlinear optical (NLO) performances of the PD and PU/PD materials were studied by the Z-scan technique under picosecond and femtosecond laser pulses. The PD has reverse saturable absorption (RSA) properties under the excitation of 532 nm 15 ps pulses, 650 and 800 nm 180 fs pulses, and a low optical limiting (OL) threshold (0.01J/cm2). The PU/PD has a larger RSA coefficient than that of the PD under 532 nm 15 ps pulses. With the enhanced RSA, the PU/PD materials exhibit excellent OL (OL) performance. Good NLO properties, high transparency, and easy processing performances make the PU/PD an excellent choice for use in OL and laser protection fields.
Development and stability analysis of an S-tapered optical fiber-based sensor structure
Authors: Xiao Lucan , Zhang Wen , Liu Xuecheng , Lang Xianzheng , Singh Ragini , Li Guoru , Xie Yiyan , Zhang Bingyuan , Kumar Santosh 
Published: February 2023

In this paper, three S-tapered fiber (STF) structures with different diameters (40, 60, and 80 µm) are fabricated using conventional single-mode fiber. First, the reproducibility of the proposed S-tapered structure is confirmed through an analysis of the diameter distribution. Considering the transmitted intensities of the three various diameter, S-tapered structures reveal that the STF with a 40 µm diameter produces more evanescent waves and is more sensitive to external refractive index variations. Therefore, the STF structure with a 40 µm diameter was evaluated for the detection of different concentration of glucose solutions, demonstrating that the structure has the potential to be utilized to develop a highly sensitive fiber sensor.
Analysis of image motion for optical remote sensing satellites staring imaging with area-array detectors
Authors: Peng Jiantao , He Yunsheng , Zheng Lianyu , Wang Shijie , Cheng Weiqiang 
Published: February 2023

In this paper, the image motion introduced by the staring action itself during optical remote sensing satellites staring imaging with area-array detectors is studied. The image motion is decomposed into the angle-rotation image motion caused by the change of observation angle, the size-scaling image motion caused by the change of observation distance, and the Earth-rotation image motion caused by the rotation of the ground object with the Earth. The theoretical derivation of the angle-rotation image motion and size-scaling image motion is conducted, and the numerical analysis of the Earth-rotation image motion is carried out. Based on the comparison among the characteristics of the three types of image motions, the conclusion is drawn that, for general staring imaging scenes, the angle-rotation image motion is dominant, followed by the size-scaling image motion and the ignorable Earth-rotation image motion. On the condition that the image motion does not exceed 1 pixel, the allowed maximum exposure time for area-array staring imaging is analyzed. It is found that the large-array satellite is not suitable for long-exposure imaging, as its allowed exposure time decreases rapidly with the increase of roll angle. A satellite with a 12k×12k area-array detector and 500 km orbit is taken as an example. The allowed exposure time is 0.88 s when roll angle of the satellite is 0°; it decreases to 0.02 s when the roll angle increases to 28°.
Beam coupling, bistability, and commutative and noncommutative behavior of self-pumping beams in BaTiO3
Authors: Venkateswarlu Putcha , Jagannath H. , George M. C. , Miahnahri A. 
Published: February 2023

BaTiO3 crystal is self-pumped by coherent beams A1 and A2 from a multilongitudinal-mode Ar+ laser. The self-pumped

A
1
*

and

A
2
*

with a 4800-Å laser showed oscillations whose frequency increases with laser intensity. They are bistable and do not coexist. With 5145 and 4765 Å,

A
1
*

and

A
2
*

coexist and are stable with minor coherent pulsations. When coexisting,

A
2
*

and

A
1
*

are strong with a 5145-Å laser while they are very weak with 4765 Å. A mutually consistent fanning occurs so that a component of each fanned beam (A1 and A2) is incident on the other beam’s grating at the correct Bragg angle to undergo total internal reflection and get into the reverse direction of the other. Thus when A1 is shut off the detector D2 of

A
2
*

shows a sharp intensity drop and similarly the D1 of

A
1
*

, when A2 is off. The counterparts of the images at D1 and D2 are seen outside the crystal between the outgoing directions of A1 and A2. When the beams A1, and A2 with 5145 Å are incoherent, the sequence A1 + A2 does not commute with A2 + A1.
Personal Information Management Systems nach TTDSG
Authors: Bernemann Julian , Kneuper Ralf 
Published: February 2023

ZusammenfassungViele Webpräsenzen nutzen Cookies, um die Interessen der Besucher zu ermitteln und Komfortfunktionen anbieten sowie individualisierte Werbung anzeigen zu können. Rechtliche Voraussetzung für derartige Cookies ist meist eine Einwilligung der Besucher. Die aktuell vorherrschende Praxis zur Einholung von Einwilligungen bei Webpräsenzen in Form von Cookie-Bannern wird aber von den Besuchern oft als nervend angesehen und verfehlt daher das eigentliche Ziel einer informierten und freiwilligen Entscheidung.Um diese Schwierigkeit zu adressieren, wurde 2021 mit dem Telekommunikation-Telemedien-Datenschutz-Gesetz das Konzept der „anerkannten Dienste zur Einwilligungsverwaltung“, meist als PIMS bezeichnet, eingeführt. Der vorliegende Beitrag analysiert dieses Konzept und arbeitet die wesentlichen Herausforderungen bei seiner Umsetzung sowie mögliche Lösungsansätze heraus. Dabei zeigen sich eine Reihe von Herausforderungen aus technischer, rechtlicher und wirtschaftlicher Sicht, für die überzeugende Lösungen derzeit nicht absehbar sind. Insbesondere erscheint der Nutzen der PIMS aus Sicht der Betreiber von Webpräsenzen und Werbenetzwerken, aber auch der Nutzer, unter den derzeitigen rechtlichen Rahmenbedingungen nicht ausreichend, dass derartige Dienste sich in der Breite durchsetzen können.
ADHD and political participation: An observational study
Authors: Waismel-Manor Israel , Kaplan Yael R. , Shenhav Shaul R. , Zlotnik Yair , Dvir Gvirsman Shira , Ifergane Gal 
Published: February 2023

Background and objective
Over the past decade, researchers have been seeking to understand the consequences of adult attention-deficit/hyperactivity disorder (ADHD) for different types of everyday behaviors. In this study, we investigated the associations between ADHD and political participation and attitudes, as ADHD may impede their active participation in the polity.

Methods
This observational study used data from an online panel studying the adult Jewish population in Israel, collected prior the national elections of April 2019 (N = 1369). ADHD symptoms were assessed using the 6-item Adult ADHD Self-Report (ASRS-6). Political participation (traditional and digital), news consumption habits, and attitudinal measures were assessed using structured questionnaires. Multivariate linear regression analyses were conducted to analyze the association between ADHD symptoms (ASRS score <17) and reported political participation and attitudes.

Results
200 respondents (14.6%) screened positive for ADHD based on the ASRS-6. Our findings show that individuals with ADHD are more likely to participate in politics than individuals without ADHD symptoms (B = 0.303, SE = 0.10, p = .003). However, participants with ADHD are more likely to be passive consumers of news, waiting for current political news to reach them instead of actively searching for it (B = 0.172, SE = 0.60, p = .004). They are also more prone to support the idea of silencing other opinions (B = 0.226, SE = 0.10, p = .029). The findings hold when controlling for age, sex, level of education, income, political orientation, religiosity, and stimulant therapy for ADHD symptoms.

Conclusions
Overall, we find evidence that individuals with ADHD display a unique pattern of political activity, including greater participation and less tolerance of others’ views, but not necessarily showing greater active interest in politics. Our findings add to a growing body of literature that examines the impact of ADHD on different types of everyday behaviors.
Endothelial glycocalyx-associated molecules as potential serological markers for sepsis-associated encephalopathy: A systematic review and meta-analysis
Authors: Baby Sheon , Reljic Tea , Villalba Nuria , Kumar Ambuj , Yuan Sarah Y. 
Published: February 2023

BackgroundSepsis-associated encephalopathy (SAE) is characterized by a diffuse cerebral dysfunction that accompanies sepsis in the absence of direct central nervous system infection. The endothelial glycocalyx is a dynamic mesh containing heparan sulfate linked to proteoglycans and glycoproteins, including selectins and vascular/intercellular adhesion molecules (V/I-CAMs), which protects the endothelium while mediating mechano-signal transduction between the blood and vascular wall. During severe inflammatory states, components of the glycocalyx are shed into the circulation and can be detected in soluble forms. Currently, SAE remains a diagnosis of exclusion and limited information is available on the utility of glycocalyx-associated molecules as biomarkers for SAE. We set out to synthesize all available evidence on the association between circulating molecules released from the endothelial glycocalyx surface during sepsis and sepsis-associated encephalopathy.MethodsMEDLINE (PubMed) and EMBASE were searched since inception until May 2, 2022 to identify eligible studies. Any comparative observational study: i) evaluating the association between sepsis and cognitive decline and ii) providing information on level of circulating glycocalyx-associated molecules was eligible for inclusion.ResultsFour case-control studies with 160 patients met the inclusion criteria. Meta-analysis of biomarkers ICAM-1 (SMD 0.41; 95% CI 0.05–0.76; p = 0.03; I2= 50%) and VCAM-1 (SMD 0.55; 95% CI 0.12–0.98; p = 0.01; I2= 82%) revealed higher pooled mean concentration in patients with SAE compared to the patients with sepsis alone. Single studies reported elevated levels of P-selectin (MD 0.80; 95% CI -17.77–19.37), E-selectin (MD 96.40; 95% Cl 37.90–154.90), heparan sulfate NS2S (MD 19.41; 95% CI 13.37–25.46), and heparan sulfate NS+NS2S+NS6S (MD 67.00; 95% CI 31.00–103.00) in patients with SAE compared to the patients with sepsis alone.ConclusionPlasma glycocalyx-associated molecules are elevated in SAE and may be useful for early identification of cognitive decline in sepsis patients.
Self-management of multiple long-term conditions: A systematic review of the barriers and facilitators amongst people experiencing socioeconomic deprivation
Authors: Woodward Abi , Davies Nathan , Walters Kate , Nimmons Danielle , Stevenson Fiona , Protheroe Joanne , Chew-Graham Carolyn A. , Armstrong Megan 
Published: February 2023

Background
Multiple long-term conditions are rising across all groups but people experiencing socioeconomic deprivation are found to have a higher prevalence. Self-management strategies are a vital part of healthcare for people with long-term conditions and effective strategies are associated with improved health outcomes in a variety of health conditions. The management of multiple long-term conditions are, however, less effective in people experiencing socioeconomic deprivation, leaving them more at risk of health inequalities. The purpose of this review is to identify and synthesise qualitative evidence on the barriers and facilitators of self-management on long-term conditions in those experiencing socioeconomic deprivation.

Methods
MEDLINE, EMBASE, AMED, PsycINFO and CINAHL Plus were searched for qualitative studies concerning self-management of multiple long-term conditions among socioeconomically disadvantaged populations. Data were coded and thematically synthesised using NVivo.

Findings
From the search results, 79 relevant qualitative studies were identified after the full text screening and 11 studies were included in the final thematic synthesis. Three overarching analytical themes were identified alongside a set of sub-themes: (1) Challenges of having multiple long-term conditions; prioritisation of conditions, impact of multiple long-term conditions on mental health and wellbeing, polypharmacy, (2) Socioeconomic barriers to self-management; financial, health literacy, compounding impact of multiple long-term conditions and socioeconomic deprivation, (3) Facilitators of self-management in people experiencing socioeconomic deprivation; maintaining independence, ‘meaningful’ activities, support networks.

Discussion
Self-management of multiple long-term conditions is challenging for people experiencing socioeconomic deprivation due to barriers around financial constraints and health literacy, which can lead to poor mental health and wellbeing. To support targeted interventions, greater awareness is needed among health professionals of the barriers/challenges of self-management among these populations.