bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of the COVID-19 pandemic on visits to the hospital emergency service in two hospitals in Spain, from March 14, 2020 to June 21, 2020
Authors: González Iria Sanlés , Valle Héctor Alonso , Abejez Laura Grimal , Molas Anna Carreres , Alonso-Molero Jéssica , Dierssen-Sotos Trinidad , Gómez-Acebo Inés 
Published: June 2023

AbstractThis study will describe trends in the use of emergency departments before and after the Spanish State of Alarm, especially in pathologies not directly related to this infection. A cross-sectional study was conducted of all visits to the emergency departments in two third-level hospitals in two Spanish communities during the Spanish State of Alarm, compared with the same period of the previous year. The variables collected included the day of the week, the time of the visit, the duration of the visit, the final destination of the patients (home, admission to a conventional hospitalization ward, admission to the intensive care unit, and death), and the diagnosis at discharge according to the International Classification of Diseases 10th Revision. During the Spanish State of Alarm period, an overall decrease in care demand of 48% was observed, which reached 69.5% in pediatric emergency departments. We also saw a drop of between 20 and 30% in time-dependent pathologies (heart attack, stroke, sepsis, poisoning). The decrease in overall attendance in the emergency departments and absence of serious pathologies, such as time-dependent diseases, observed during the Spanish State of Alarm compared to the previous year highlights the need to strengthen the messages addressed to the population to encourage them to seek care without delay in case of alarming symptoms and reduce the high morbidity and mortality rate if the diagnosis is delayed.
An annotated checklist of arthropods associated with the root vole Microtus oeconomus
Authors: Karbowiak Grzegorz , Stanko Michal , Rychlik Leszek , Werszko Joanna 
Published: June 2023

AbstractIn the literature, 114 species of arthropods associated to Microtus oeconomus have been reported in the entire area of their occurrence. There are eight species of hard ticks, 52 species of gamasid and chigger mites, 47 species of fleas and seven species of sucking lice. In general, the dominant parasites of the Palearctic and Nearctic root vole populations are either western or entire Palearctic species. The analysis of the geographical range of their occurrence indicates that most of them occur both in Europe and Asia. Throughout Europe, Asia and America (Holarctic realm), root voles share 13 species of mites, seven species of fleas, and three species of sucking lice. Ectoparasite species split between two continents, most of them are found in both Europe and Asia (Palearctic region). Here belong three species of ixodid ticks, sixteen species of mites, seven species of fleas and two species of sucking lice. In Asia and the North American continents (Holarctic realm excluding Europe) populations of root voles share only one tick species, two species of mites, three species of fleas and one species of sucking lice. Of the parasitic species found only in Western Palearctic, excluding Asia, root voles are infested by three ixodid tick species, 14 mite species, and 13 flea species. Among the parasitic arthropods affecting root vole only in Eastern Palearctic, excluding Europe, one tick species, four mite species and seven flea species occur. There are only three mite species, ten flea and one sucking louse species on voles that inhabit North America (Nearctic region). Associated arthropods are obligate and facultative parasites or nidicolic and edaphic species. Seasonal changes in numbers of ticks, parasitic mites, sucking lice, fleas have also been observed.
An Image Catalogue of Micron- and Sub-micron-Sized Constrictions Fabricated with the Femtosecond Laser and Created with the AFM
Authors: Umenne Patrice 
Published: June 2023

AbstractIn this article a series of constrictions in the micron and sub-micron range fabricated with the femtosecond laser on superconducting $${\mathrm{YBa}}_{2}{\mathrm{Cu}}_{3}{\mathrm{O}}_{7}$$

YBa
2

Cu
3

O
7

thin films is scanned with an atomic force microscope (AFM). The AFM images of the resulting constrictions are depicted. The width of the constrictions fabricated range from 1.24 µm micron dimension to 812 nm in the sub-micron range. The laser ablation spot size or diameter is set at 15.8 µm for the femtosecond laser and the separation distance between the centers of the laser ablation spots is varied between (16–17) µm as a result generating the variable constriction widths for the different superconductive bridges. The images of the fabricated micron and sub-micron constrictions are shown as a catalogue in the article. The AFM images give the surface morphology, dimensions, and physical continuity of the fabricated constriction qubits. The I–V characteristics of the constrictions are measured and validate the electrical continuity and superconductivity of the fabricated constrictions.
The Loss of Temporal Muscle Volume is Associated with Poor Outcome in Patients with Subarachnoid Hemorrhage: An Observational Cohort Study
Authors: Kofler Mario , Reitmeir Philipp , Glodny Bernhard , Rass Verena , Lindner Anna , Ianosi Bogdan A. , Gaasch Max , Schiefecker Alois J. , Putnina Lauma , Beer Ronny , Rhomberg Paul , Schmutzhard Erich , Pfausler Bettina , Helbok Raimund 
Published: June 2023

Abstract
Background
Intensive care unit (ICU) acquired weakness is a major contributor to poor functional outcome of ICU patients. Quantification of temporal muscle volume assessed on routine computed tomography (CT) scans may serve as a biomarker for muscle wasting in patients suffering from acute brain injury.

Methods
This is a retrospective analysis of prospectively collected data. Temporal muscle volume was assessed on head CT scans of consecutive patients with spontaneous subarachnoid hemorrhage within prespecified time frames (on admission, then weekly ± 2 days). Whenever possible, temporal muscle volume was assessed bilaterally and averaged for the analysis. Poor functional outcome was defined as a 3-month modified Rankin Scale Score ≥ 3. Statistical analysis was performed using generalized estimating equations to handle repeated measurements within individuals.

Results
The analysis comprised 110 patients with a median Hunt & Hess score of 4 (interquartile range 3–5). Median age was 61 (50–70) years, 73 patients (66%) were women. Baseline temporal muscle volume was 18.5 ± 0.78 cm3 and significantly decreased over time (p < 0.001) by a mean of 7.9% per week. Higher disease severity (p = 0.002), hydrocephalus (p = 0.020), pneumonia (p = 0.032), and bloodstream infection (p = 0.015) were associated with more pronounced muscle volume loss. Patients with poor functional outcome had smaller muscle volumes 2 and 3 weeks after subarachnoid hemorrhage compared with those with good outcome (p = 0.025). The maximum muscle volume loss during ICU stay was greater in patients with poor functional outcome (− 32.2% ± 2.5% vs. − 22.7% ± 2.5%, p = 0.008). The hazard ratio for poor functional outcome was 1.027 (95% confidence interval 1.003–1.051) per percent of maximum muscle volume loss.

Conclusions
Temporal muscle volume, which is easily assessable on routine head CT scans, progressively decreases during the ICU stay after spontaneous subarachnoid hemorrhage. Because of its association with disease severity and functional outcome, it may serve as a biomarker for muscle wasting and outcome prognostication.
Blood Pressure Changes in Association with Nimodipine Therapy in Patients with Spontaneous Subarachnoid Hemorrhage
Authors: Rass Verena , Kindl Philipp , Lindner Anna , Kofler Mario , Altmann Klaus , Putnina Lauma , Ianosi Bogdan-Andrei , Schiefecker Alois J. , Beer Ronny , Pfausler Bettina , Helbok Raimund 
Published: June 2023

Abstract
Background
Nimodipine is recommended to prevent delayed cerebral ischemia in patients with spontaneous subarachnoid hemorrhage (SAH). Here, we studied hemodynamic side effects of different nimodipine formulations (per os [PO] and intravenous [IV]) in patients with SAH undergoing continuous blood pressure monitoring.

Methods
This observational cohort study includes consecutive patients with SAH (271 included in the IV group, 49 in the PO group) admitted to a tertiary care center between 2010 and 2021. All patients received prophylactic IV or PO nimodipine. Hemodynamic responses were evaluated based on median values within the first hour after continuous IV nimodipine initiation or PO nimodipine application (601 intakes within 15 days). Significant changes were defined as > 10% drop in systolic blood pressure (SBP) or diastolic blood pressure from baseline (median values 30 min before nimodipine application). With the use of multivariable logistic regression, risk factors associated with SBP drops were identified.

Results
Patients were admitted with a median Hunt & Hess score of 3 (2–5; IV 3 [2–5], PO 1 [1–2], p < 0.001) and were 58 (49–69) years of age. Initiation of IV nimodipine was associated with a > 10% SBP drop in 30% (81/271) of patients, with a maximum effect after 15 min. A start or increase in noradrenaline was necessary in 136/271 (50%) patients, and colloids were administered in 25/271 (9%) patients within 1 h after IV nimodipine initiation. SBP drops > 10% occurred after 53/601 (9%) PO nimodipine intakes, with a maximum effect after 30–45 min in 28/49 (57%) patients. Noradrenaline application was uncommon (3% before and 4% after nimodipine PO intake). Hypotensive episodes to an SBP < 90 mm Hg were not observed after IV or PO nimodipine application. In multivariable analysis, only a higher SBP at baseline was associated with a > 10% drop in SBP after IV (p < 0.001) or PO (p = 0.001) nimodipine application, after adjusting for the Hunt & Hess score on admission, age, sex, mechanical ventilation, days after intensive care unit admission, and delayed cerebral ischemia.

Conclusions
Significant drops in SBP occur in one third of patients after the start of IV nimodipine and after every tenth PO intake. Early recognition and counteracting with vasopressors or fluids seems necessary to prevent hypotensive episodes.
A demonstration based on multi-omics transcriptome sequencing data revealed disulfidptosis heterogeneity within the tumor microenvironment of esophageal squamous cell carcinoma
Authors: Liu Fuxing , Yuan Donglan , Liu Xia , Zhuo Shichao , Liu Xinyun , Sheng Haihui , Sha Min , Ye Jun , Yu Hong 
Published: June 2023

Abstract
Background
It is of great concern to identify prognostic signatures for the prediction and prediction of esophageal squamous cell carcinoma (ESCC), which is the lethal pathological type of malignancy.

Method
Bulk RNA sequencing and scRNA-seq data were retrieved from GSE53624, GSE53622, and GSE188900. Disulfidptosis-related differentially expressed genes (DEGs) were identified between disulfidptosis-high score and disulfidptosis-low score groups. Functional annotation of DEGs were analyzed by Gene Ontology (GO). Consistent clustering and co-expression modules were analyzed, and then constructed a risk score model via multivariate Cox regression analysis. Immune infiltration and immunotherapy response analyses were conducted based on risk score. qRT-PCR, colony formation assay, and flow cytometry analysis were conducted in KYSE-150 and TE-1 cell lines.

Results
Seven genes (CD96, CXCL13, IL2RG, LY96, TPK1, ACAP1, and SOX17) were selected as marker genes. CD96 and SOX17 are independent prognostic signatures for ESCC patients, with a significant correlation with infiltrated immune cells. ESCC patients had worse response to nivolumab in the high-risk group. Through cellular experiments, we found that CD96 expression was associated with apoptosis and cell cycle ESCC cells.

Conclusion
In a word, the risk score based on disulfidptosis is associated with prognosis and the immune microenvironment, which may direct immunotherapy of ESCC. The key gene of risk score, namely CD96, plays a role in proliferation and apoptosis in ESCC. We offer an insight into the exploration of the genomic etiology of ESCC for its clinical management.
Characterization and performance test of phenolphthalein poly(aryl ether ketone) fractionated by incremental poor solvent fractionation
Authors: Qian Zengxu , Jiang Jingwei , Sun Yunlong , Yuan Qiliang , Wang Zhichao , Wang Zhipeng , Zhou Guangyuan 
Published: June 2023

Abstract
Though phenolphthalein poly(aryl ether ketone) (PEK-C) has gained attention as a special engineering plastic materials by virtue of its good thermal stability and favorable mechanical properties, its applications are limited due to its wide PDI during polymerization, which result in poor mechanical properties of PEK-C. In order to investigate the effect of molecular weight and polydispersity index (PDI) on PEK-C, an incremental poor solvent fractionation method was used to fractionate PEK-C. The process produced a series of grades with decreasing molecular weight and PDI. The LCP (linear cloud point) equation was combined with the grading method to find the optimal PEK-C/DMAc/ Non-solvent additives (NSA) system, which can be used to improve the grading efficiency. The obtained results showed that the incremental poor solvent fractionation method with the PEK-C/DMAc/EA system made the molecular weight distributed in the range of 25 ~ 113 kDa, PDI mostly distributed in the range of 1.1 ~ 1.4, and the narrowest PDI to reach 1.13, which could not be obtained through the condensation reaction. Meanwhile, we can also achieve expanded production. By fractionation, the elastic modulus of PEK-C film could be increased by up to 22.6%, elongation at break by up to 38.3%, the fracture strength by up to 38.2%, and impact strength of the sheest by up to 41.2%, while the polymer still maintained good thermal and UV shielding properties. This unique Polymer/Solution/NSA system can yield an effective design strategy for controlling its molecular weight and PDI and improving its mechanical performance.

Graphical abstract
PEK-C (NM01) was fractionated by incremental poor solvent fractionation. Due to the weak pr ecipitation strength of EA to PEK-C, a large number of grades can be obtained by expanding the classification. Through the method of adding precipitant, NM01 was fractionated into two parts with different molecular weights and PDIs. The impact strength of these grades could be improved well.
Industrial Vestiges: Legacies of Ancillary Impacts of Resource Development
Authors: Venovcevs Anatolijs 
Published: June 2023

AbstractThis article offers a different way to understand the heritage of extractive industries by exploring the material afterlives of what has been termed the “ancillary impacts of resource development”—a variety of quarries, forest cuts, transportation corridors, and power lines that surround industrial operations, especially those created in areas distant from established industrial population centers. To study this, the article expands upon the concept of “vestige” to explore the landscapes around two single-industry mining towns in Kola Peninsula, Russia, and in Labrador, Canada, by specifically focusing on two abandoned quarries located in each. The results highlight the need to explore developments that trail behind industrial settlement of colonial hinterlands. By focusing specifically on the afterlives of such developments, the article demonstrates how chronological and geographical boundaries of resource extraction are blurred over time, creating a deep, unruly, self-perpetuating set of legacies.
Searching for socio-ecological approaches to increase Balanites trees through local small-scale conservation in the conservancies adjoining the Maasai Mara, Kenya
Authors: Grose Margaret J. , Nampaso Moses Titimet 
Published: June 2023

AbstractOn the edges of the Maasai Mara in western Kenya there are 15 conservancies, where herds of wildlife, cattle, sheep, goats, and predators are found with Balanites aegyptiaca, an iconic and much-photographed tree known by many names, such as desert date, or more simply, Balanites. Most individuals are 80–90 years old, yet the tree has a life-expectancy of about 120 years. Lack of young trees is due to grazing and browsing impacts from sheep and goat herding that began about eighty years ago. Protecting young naturally regenerated trees is difficult as they are also grazed by large herbivores such as elephants and giraffe. In this perspective essay we describe botanical and social approaches to enable small-scale conservation in a remote area where no work on Balanites revegetation has been done previously. There are two core approaches. First, collecting seed from both superior mother trees and more widely to achieve a source of genetic diversity and second, to work with landowners and other locals on methods to protect new saplings from sheep and goats. These avenues of action in this poor rural area will set the stage for further practical research and assessment of methods to improve the regional survival of Balanites.
Personal vehicle use and food security among US adults who are primary shoppers for households with children
Authors: Antrum Curtis Jalen , Waring Molly E. , Cooksey Stowers Kristen 
Published: June 2023

AbstractIn 2020, 2.9 million households with children were food secure. Previous studies have demonstrated that reduced car access may contribute to issues of food security. This study examines whether using a personal vehicle by primary shoppers of households with children is associated with food security. Data were from US adults who were primary shoppers for households with children (N = 997) in the National Health and Nutrition Examination Survey 2017–2018. Participants reported their means of transportation to complete grocery shopping, which was categorized as using a personal vehicle or another mode of transportation. Household food security was measured using the US Food Security Survey Module and categorized as full food security, marginal food security, low food security, or very low food security. Multinomial logistic regression models estimated the association between transportation mode and food security. Adjusted models included age, race/ethnicity, education, and poverty-to-income ratio variables. 3.8% (SE: 0.6%) of US adults who are primary shoppers for households with children did not use a personal vehicle for grocery shopping. US adults who used a personal vehicle for grocery shopping were less likely to report very low food security [22.1% (SE: 7.4%) vs. 8.5% (SE: 1.3%), aOR = 0.4, 95% CI 0.1–1.0]. There were no differences in marginal food security [18.3% (SE: 3.3%) vs. 13.1% (SE: 1.7%), aOR = 0.9, 95% CI 0.6–1.5] or low food security [30.6% (SE: 8.7%) vs. 16.1% (SE: 1.7%), aOR = 0.6, 95% CI 0.2–1.7]. Future research and interventions should address how transportation access may contribute to food security in families with children.
UAV-assisted counts of group size facilitate accurate population surveys of the Critically Endangered cao vit gibbon Nomascus nasutus
Authors: Wearn Oliver R. , Trinh-Dinh Hoang , Le Quyet Khac , Nguyen Tho Duc 
Published: June 2023

AbstractGibbons are often difficult to observe in dense forest habitats using traditional ground-based methods. This makes it challenging to estimate group sizes and, in turn, population sizes. This has proven to be a key constraint on accurate monitoring of the last remaining population of the Critically Endangered cao vit gibbon Nomascus nasutus. However, new technologies are beginning to circumvent the problems associated with traditional methods. We hypothesized that, by using an unoccupied aerial vehicle (UAV) equipped with thermal and standard (RGB) cameras, we could obtain more accurate group size counts than by using ground-based observations, as fewer gibbons would be missed. We tested this during a population survey of the cao vit gibbon, finding that the thermal video footage revealed additional individuals that were not counted by ground-based surveyors. Statistically, there was strong evidence (93% probability) that UAV-derived counts were higher (by 41%) than concurrent ground-based counts. We recorded six primate groups of three species (cao vit gibbon, rhesus macaque Macaca mulatta and Assamese macaque Macaca assamensis), including 24 gibbons across four groups (c. 20% of the global population). The RGB video footage also revealed seven female gibbons, two of which were carrying infants, providing vital group composition data. These data have contributed directly to a more accurate population survey of the species than would have been possible using direct observation only. We anticipate more widespread use of UAVs in the study of gibbons and other threatened species, leading to a more robust evidence base for their conservation.
The DIMA Network: Bridging boundaries via shared scientific interests
Authors: van Hardenbroek Maarten , Edwards Mary , Blyakharchuk Tatiana , Lozhkin Anatoly , Bezrukova Elena , Grenaderova Anna , Ryabogina Natalia , Antipina Tatiana , Cherepanova Marina , Anderson Patricia 
Published: June 2023

Abstract
The DIMA Network (Developing Innovative Multi-proxy Analyses – in Siberia and the Russian Far East (SRFE)) started from a small nucleus of palaeoenvironmental researchers in the UK and SRFE at a workshop in 2008 and currently includes researchers from over 25 institutions. The mutual interest in creating long-term records of environmental change was rekindled during workshops in Magadan (2018), Tomsk (2018) and Southampton (2019). These events were organised to connect researchers from the UK and SRFE with these aims: (1) provide training in new techniques and methods, (2) facilitate knowledge transfer about local sites and conditions, (3) stimulate large-scale collaborative projects across SRFE and (4) inspire a new generation of palaeoenvironmental researchers.
The Atlas of Morocco: A Plume‐Assisted Orogeny
Authors: Lanari R. , Faccenna C. , Natali C. , Şengül Uluocak E. , Fellin M. G. , Becker T. W. , Göğüş O. H. , Youbi N. , Clementucci R. , Conticelli S. 
Published: June 2023

AbstractWe explore the connections between crustal shortening, volcanism, and mantle dynamics in the Atlas of Morocco. In response to compressional forces and strain localization, this intraplate orogen has evolved far from convergent plate margins. Convective effects, such as lithospheric weakening and plume‐related volcanism, contributed in important ways to the building of high topography. We seek to better understand how crustal and mantle processes interacted during the Atlas' orogeny by combining multiple strands of observations, including new and published data. Constraints on crustal and thermal evolution are combined with new analyses of topographic evolution, petrological, and geochemical data from the Anti‐Atlas volcanic fields, and a simple numerical model of the interactions among crustal deformation, a mantle plume, and volcanism. Our findings substantiate that: (a) crustal deformation and exhumation accelerated during the middle/late Miocene, contemporaneous with the onset of volcanism; (b) volcanism has an anorogenic signature with a deep source; (c) a dynamic mantle upwelling supports the high topography. We propose that a mantle plume and the related volcanism weakened the lithosphere beneath the Atlas and that this favored the localization of crustal shortening along pre‐existing structures during plate convergence. This convective‐tectonic sequence may represent a general mechanism for the modification of continental plates throughout the thermo‐chemical evolution of the supercontinental cycle.