bluuebunny/crossref_metadata_2025_split huggingface dataset:
Early onset anorexia nervosa: Multidisciplinary hospital intervention in a 1‐year follow‐up study
Authors: Pruccoli Jacopo , Parmeggiani Antonia 
Published: February 2023

AbstractBackgroundEarly onset anorexia nervosa (EOAN) is a subclassification of AN, defined by an onset before 14 years, and characterized by specific demographic, neuropsychological, and clinical features. The present study aims to provide naturalistic data on a wide sample with EOAN, focusing on psychopathological and nutritional changes occurring in the context of a multidisciplinary hospital intervention, as well as the rate of rehospitalizations during a 1‐year follow‐up.MethodObservational, naturalistic study adopting standardized criteria for EOAN (onset before 14 years). EOAN were compared to adolescent‐onset AN (AOAN) patients (onset after 14 years) by demographic, clinical, psycho and treatment variables. Psychopathology was assessed at admission (T0) and discharge (T1) with self‐administered psychiatric scales for children and adolescents (SAFA) subtests for Eating Disorders, Anxiety, Depression, Somatic symptoms, and Obsessions. Then, potential differences of T0–T1 changes in psychopathological and nutritional variables were assessed. Finally, rates of re‐hospitalizations at 1‐year post‐discharge follow‐up were assessed with Kaplan–Meier analyses.ResultsTwo‐hundred thirty‐eight AN individuals (EOAN = 85) were enrolled. When compared to AOAN, EOAN participants were more frequently males (X2 = 5.360, p = .021), more frequently received nasogastric‐tube feeding (X2 = 10.313, p = .001), and risperidone (X2 = 19.463, p < .001), obtained a greater T0‐T1 improvement in body‐mass index percentage (F[1.229] = 15.104, p < .001, η2 = 0.030), with higher 1‐year freedom from re‐hospitalization (hazard ratio, 0.47; Log‐rank: X2 = 4.758, p = .029).ConclusionIn this study, describing the broadest EOAN sample available in literature so far, EOAN patients received specific interventions and obtained better outcomes at discharge and follow‐up when compared to AOAN. Longitudinal, matched studies are required.
Conditional knockout of transient receptor potential melastatin 7 in the enamel epithelium: Effects on enamel formation
Authors: Shin Masashi , Matsushima Aya , Kajiya Hiroshi , Okamoto Fujio , Ogata Kayoko , Oka Kyoko , Ohshima Hayato , Bartlett John D. , Okabe Koji 
Published: February 2023

AbstractTransient receptor potential melastatin 7 (TRPM7) is a unique ion channel connected to a kinase domain. We previously demonstrated that Trpm7 expression is high in mouse ameloblasts and odontoblasts, and that amelogenesis is impaired in TRPM7 kinase‐dead mice. Here, we analyzed TRPM7 function during amelogenesis in Keratin 14‐Cre;Trpm7fl/fl conditional knockout (cKO) mice and Trpm7 knockdown cell lines. cKO mice showed lesser tooth pigmentation than control mice and broken incisor tips. Enamel calcification and microhardness were lower in cKO mice. Electron probe microanalysis (EPMA) showed that the calcium and phosphorus contents in the enamel were lower in cKO mouse than in control mice. The ameloblast layer in cKO mice showed ameloblast dysplasia at the maturation stage. The morphological defects were observed in rat SF2 cells with Trpm7 knockdown. Compared with mock transfectants, the Trpm7 knockdown cell lines showed lower levels of calcification with Alizarin Red‐positive staining and an impaired intercellular adhesion structures. These findings suggest that TRPM7 is a critical ion channel in enamel calcification for the effective morphogenesis of ameloblasts during amelogenesis.
Traumatic brain injury and relationship distress during military deployment and reunion
Authors: Knobloch Leanne K. , Abendschein Bryan 
Published: February 2023

AbstractObjectiveThis study seeks to advance the literature by disentangling the effects of deployment‐acquired traumatic brain injury (TBI) from comorbid postconcussive symptoms and PTSD symptoms on relationship distress.BackgroundBecause TBI poses challenges to military marriages, understanding the predictors of relationship distress after TBI is important for helping service members cope with the effects of the injury.MethodSurvey data from the U.S. Army STARRS Pre–Post Deployment Study, collected from 2,585 married service members before and after a combat deployment to Afghanistan, evaluated predictors of relationship distress 9 months after homecoming.ResultsDeployment‐acquired TBI corresponded with more relationship distress controlling for predeployment brain health, but its predictive power was eclipsed by concurrent postconcussive symptoms and concurrent PTSD symptoms. Concurrent PTSD symptoms accounted for twice as much variance in relationship distress than concurrent postconcussive symptoms.ConclusionTargeting and treating comorbid conditions may be essential for supporting military marriages after TBI.Implications: Military command, policymakers, and medical professionals may find value in broadening support services for TBI to include resources addressing postconcussive symptoms, PTSD symptoms, and relationship distress.
Shrub and precipitation interactions shape functional diversity of nematode communities on the Qinghai–Tibet Plateau
Authors: Zhang Anning , Chen Shuyan , Chen Jingwei , Cui Hanwen , Jiang Xiaoxuan , Xiao Sa , Wang Jiajia , Gao Haining , An Lizhe , Cardoso Pedro 
Published: February 2023

AbstractLand use and climate change alter biodiversity patterns and ecosystem functioning worldwide. Land abandonment with consequent shrub encroachment and changes in precipitation gradients are known factors in global change. Yet, the consequences of interactions between these factors on the functional diversity of belowground communities remain insufficiently explored. Here, we investigated the dominant shrub effects on the functional diversity of soil nematode communities along a precipitation gradient on the Qinghai–Tibet Plateau. We collected three functional traits (life‐history C–P value, body mass, and diet) and calculated the functional alpha and beta diversity of nematode communities using kernel density n‐dimensional hypervolumes. We found that shrubs did not significantly alter the functional richness and dispersion, but significantly decreased the functional beta diversity of nematode communities in a pattern of functional homogenization. Shrubs benefited nematodes with longer life‐history, larger body mass, and higher trophic levels. Moreover, the shrub effects on the functional diversity of nematodes depended strongly on precipitation. Increasing precipitation reversed the effects shrubs have on the functional richness and dispersion from negative to positive but amplified the negative effects shrubs have on functional beta diversity of nematodes. Benefactor shrubs had stronger effects on the functional alpha and beta diversity of nematodes than allelopathic shrubs along a precipitation gradient. A piecewise structural equation model showed that shrubs and its interactions with precipitation indirectly increased the functional richness and dispersion through plant biomass and soil total nitrogen, whereas it directly decreased the functional beta diversity. Our study reveals the expected changes in soil nematode functional diversity following shrub encroachment and precipitation, advancing our understanding of global climate change on nematode communities on the Qinghai–Tibet Plateau.
REDUCING RECOMMENDATION INEQUALITY VIA TWO‐SIDED MATCHING: A FIELD EXPERIMENT OF ONLINE DATING
Authors: Chen Kuan‐Ming , Hsieh Yu‐Wei , Lin Ming‐Jen 
Published: February 2023

AbstractLeading dating platforms usually recommend only a small fraction of users based on users' popularity and similarity, leading to recommendation inequality. We use a stylized matching model from economics to modify existing algorithms to reduce inequality. We evaluate the proposed method through a large‐scale field experiment on a dating platform. Experiment results suggest that our recommender reduces inequality, improves predictive accuracy, and leads to substantially more matched couples than other competing algorithms.
Development and validation of two versions of the Nurse–Patient Mutuality in Chronic Illness scale
Authors: Cilluffo Silvia , Bassola Barbara , Iovino Paolo , Lusignani Maura 
Published: February 2023

AbstractAimsThe aim of the study was to develop and psychometrically test the Nurse–Patient Mutuality in Chronic Illness (NPM‐CI) scale in two versions, one for nurses and one for patients.MethodA multiphase methodological study was conducted. In the first phase, a qualitative investigation was conducted through interviews and an analysis of the content; inductively, the items of two instruments were generated, one for nurses and one for patients. In the second phase, the content and face validity were assessed through the expert consensus method. In the third phase, exploratory factor analysis (EFA), Cronbach's alpha test, intraclass correlation and Pearson correlation coefficients were conducted to estimate construct, criterion validity and instrument reliability. For each phase, the sample included nurses and patients recruited from a large hospital in Northern Italy. Data collection was conducted between June and September 2021.ResultsNurse and patient versions of the NPM‐CI scale were developed. Two rounds of consensus reduced the items from 39 to 20; content validity index ranged between 0.78 and 1, content validity ratio was 0.94. Face validity indicated clarity and comprehensibility of the items. EFA identified three latent factors for both the scales. Internal consistency was satisfactory, with Cronbach's alphas ranging between .80 and .90. Test–retest stability was suggested, with an intraclass correlation coefficient of .96 (nurse scale) and .97 (patient scale). Predictive validity was established, with a Pearson correlation coefficient of .43 (nurse scale) and 0.55 (patient scale) between the mutuality scales and satisfaction in providing and receiving care.ConclusionThe results suggest that the NPM‐CI scales are sufficiently valid and reliable for the clinical practice among chronic illness patients and the nurses caring for them. A more in‐depth exploration of this construct in the context of nursing and patient outcomes is warranted.Patient or Public ContributionPatients were involved in all study phases.ImpactMutuality is fundamental in the relationship between nurse and patient, based on trust, equality, reciprocity, and mutual respect. The NPM‐CI scale was developed and psychometric estimated through a multiphase study in both nurse and patient versions. The NPM‐CI scale measures the factors of ‘developing and going beyond’, ‘being the point of reference’ and ‘deciding and sharing care’. The NPM‐CI scale allows us to measure mutuality in clinical practice and research. Expected outcomes and influencing factors for patients and nurses could be associated.
Association between serum uric acid levels and achievement of target blood pressure among Japanese community residents with hypertension
Authors: Yokokawa Hirohide , Suzuki Mai , Aoki Nozomi , Fukuda Hiroshi , Sato Yuki , Hisaoka Teruhiko , Naito Toshio 
Published: February 2023

AbstractThe authors examined the sex‐specific association between serum uric acid (SUA) levels and achievement of target blood pressure among Japanese patients with hypertension. This cross‐sectional study was conducted between January 2012 and December 2015 and examined 17 113 eligible participants (6499 men; 10 614 women) with hypertension among 66 874 Japanese community residents who underwent voluntary health checkups. Multivariate analysis was used to estimate the association between high SUA level (≥7.0 mg/dL for men and ≥6.0 mg/dL for women) and “therapeutic failure” in achieving target blood pressure (BP) of 140/90 and 130/80 mmHg in both sexes. Multivariate analysis revealed that high SUA level was significantly associated with failure to achieve the 130/80 mmHg treatment goal among men (AOR = 1.24, 95% CI = 1.03–1.50, p = .03). Among women, high SUA level was significantly associated with failure to achieve both the 130/80 and 140/90 mmHg treatment goals (AOR = 1.33, 95% CI = 1.20–1.47, p < .01 and AOR = 1.17, 95% CI = 1.04–1.32, p < .01, respectively). Each increase in SUA quartile was positively associated with increases in systolic BP (SBP) and diastolic BP (DBP) (p < .01 for trend) in both sexes. SBP and DBP in each quartile (Q2–Q4) were also significantly higher compared with those of Q1 in both sexes (p < .01). Our data confirms the difficulties in maintain goal BP control in those with elevated SUA.
Contribution of periodontal health in cardiovascular secondary prevention: Analyses on hospitalized patients in cardiology units
Authors: Hamaya Rikuta , Yonetsu Taishi , Aoyama Norio , Shiheido‐Watanabe Yuka , Tashiro Akira , Niida Takayuki , Isobe Mitsuaki , Maejima Yasuhiro , Iwata Takanori , Sasano Tetsuo 
Published: February 2023

AbstractAimTo investigate the association between dental health and incident cardiovascular disease (CVD) in secondary prevention setting.Materials and MethodsA total of 888 patients with known CVD hospitalized in the cardiology unit were prospectively enrolled. We assessed the association between missing teeth and three variables of periodontitis and major adverse cardiovascular events (MACE), defined as a composite of cardiac death, acute myocardial infarction, stroke and hospital re‐admission for congestive heart failure.ResultsDuring a median (Q1, Q3) follow‐up of 4.6 (1.4, 6.7) years, an additional missing tooth was associated with a 3% (95% confidence interval [CI]: 1%–5%) higher hazard of MACE (p = .004). Compared with patients with 0 to ≤4 missing teeth, periods free from MACE (95% CI) by 5 years of follow‐up were, on average, shorter by 0.17 (−0.04 to 0.37) years, 0.26 (0.04–0.49) years and 0.59 (0.34–0.85) years in patients with 5 to ≤7, 8 to ≤13 and >13 missing teeth, respectively. No significant associations were observed between periodontal measures and MACE incidence.ConclusionsIn hospitalized patients with existing CVD, the total number of missing teeth was associated with incident MACE.
A method for long‐term retention of pop‐up satellite archival tags (PSATs) on small migratory fishes
Authors: Naisbett‐Jones Lewis C. , Branham Creed , Birath Shayla , Paliotti Savannah , McMains Andrew R. , Joel Fodrie Frederick , Morley James W. , Buckel Jeffrey A. , Lohmann Kenneth J. 
Published: February 2023

AbstractAchieving long‐term retention of pop‐up satellite archival tags (PSATs) has proven difficult for all fishes but is particularly challenging for small migrant species due to the relatively large size of tags. In this study, the authors tested the latest and smallest PSAT model on the market, the mark‐report satellite tag (mrPAT), and developed a simple, cost‐effective method of tag attachment on sheepshead Archosargus probatocephalus (Walbaum 1792), a small marine fish. During laboratory trials, the method of tag attachment used in this study outperformed the existing methods with two c. 40 cm fish retaining their tags for 3 months (the duration of the laboratory study). During field deployments, data were successfully obtained for 17 of the 25 tagged fish [37–50 cm fork length (FL)]. Of these, 14 tags (82%) remained on the fish until the pre‐programmed release date resulting in tag retention times of up to 172 days (mean: 140 days). The investigation represents the first extensive study into the feasibility of PSATs for monitoring fishes in this size range. The authors demonstrate that their method of attachment and this latest PSAT model are feasible for c. 5‐month deployments on fishes that are relatively small (c. 45 cm FL). These results with A. probatocephalus represent a potentially significant advance in PSAT methodology for fishes of this size. Future investigations are needed to determine if this method is transferrable to other species in the same size range.
On‐site test and numerical analysis on temperature field of an underground grain silo under static storage
Authors: Jin Libing , Li Chuang , Duan Haijing , Wang Zhenqing , Xue Yaqi , Wu Qiang 
Published: February 2023

AbstractGrain temperature is one of the most important factors affecting grain security. The temperature field of the underground ecological granary was investigated by field experiment and numerical simulation. The experiment was carried out in the underground grain silo (UGS), a full‐scale engineering model. The UGS temperature data for one consecutive year were obtained through daily on‐site periodic monitoring. Based on the boundary conditions of UGS, including ambient air temperature, heat transfer coefficient, and underground constant temperature zone, a two‐dimensional rotational axisymmetric model is constructed. Then the temperature field of UGS was analyzed by numerical method. The simulation results coincide with the test results, and the conclusions are as follows: (1) The average temperature of UGS is maintained at around 20°C, the upper zone is easy to be affected by the outside, but the central and bottom zone are relatively stable. (2) The average temperature of grain is always below 17°C, and the temperature of the surface layer has inevitable fluctuations due to the influence of the ambient air temperature. (3) The average temperature of grain changes significantly in the early stage, but as time goes on, the grain temperature tends to the temperature in the constant temperature zone.Practical ApplicationsCompared with the traditional above‐ground granaries underground granary has the advantages of land saving, grain storage capacity per unit area and long‐term storage of grain at low temperature. Now we have built two large underground granaries to study the various properties of underground granaries, which will be put into normal use later. By studying the temperature field of underground granary, exploring the change of temperature field of long‐term grain storage is beneficial to the popularization and application of underground granary, which is of great significance to ensure food security.
Cryptocurrency, Security, and Financial Intermediation
Authors: GLENN NICHOLAS , REED ROBERT 
Published: February 2023

AbstractIn recent years, the use of cryptocurrencies has increased. As these currencies continue to play a larger role, they eventually will be an important component of banking system activity. Moreover, in addition to the standard role of financial intermediaries to facilitate lending, intermediaries can be valuable firms that help provide safekeeping of tokens. The objective of this paper is to demonstrate these important functions in a microfounded model of monetary exchange. Furthermore, we also consider the possibility that central banks issue their own digital currencies that may affect the level of intermediation in the private banking system.
The effects of mandibular advancement appliance therapy on jaw‐closing muscle activity time‐related to oxygen desaturations: A randomised controlled trial
Authors: Kuang Boyuan , Aarab Ghizlane , Lobbezoo Frank , Tran Buu T. , Arcache Patrick , Lavigne Gilles , Huynh Nelly 
Published: February 2023

AbstractBackgroundPrevious study showed that in individuals with obstructive sleep apnea (OSA), the contractions of masseter muscles after respiratory events can be nonspecific motor phenomena, dependent on the duration of respiratory arousals rather than the occurrence of the respiratory events. However, the role of intermittent hypoxia in the occurrence of jaw‐closing muscle activities (JCMAs) was not taken into consideration. An exposure to intermittent hypoxia has been shown to initiate a series of activities, including muscular sympathetic activity in patients with OSA.ObjectiveTo determine the effects of mandibular advancement appliance (MAA) therapy on JCMA time‐related to oxygen desaturation with and without arousal in individuals with OSA.MethodsEighteen individuals with OSA (age: 49.4 ± 9.8 years, apnea‐hypopnea index (AHI): 10.0|18.4|30.3, JCMA index: 1.7|4.3|5.6), participated in a randomised controlled crossover clinical trial, in which two ambulatory polysomnographic recordings were performed: one with MAA in situ and the other without MAA in situ. JCMAs were recorded bilaterally from both masseter and temporalis muscles.ResultsThere was no significant effect of the MAA on the overall JCMA index (Z = −1.372, p = .170). With the MAA in situ, JCMA index time‐related to oxygen desaturation with arousal significantly decreased (Z = −2.657, p = .008), while there was no significant effect of the MAA on the JCMA index time‐related to oxygen desaturation without arousal (Z = −0.680, p = .496).ConclusionEffective mandibular advancement appliance therapy significantly reduces jaw‐closing muscle activities time‐related to oxygen desaturation with arousal in individuals with OSA.
Network meta‐analysis of platelet‐rich fibrin in periodontal intrabony defects
Authors: Ye Lianmei , Mashrah Mubarak Ahmed , Ge Linhu , Fang Ying , Guo Xueqi , Ge Qing , Wang Liping 
Published: February 2023

AbstractObjectivesTo evaluate the effect of platelet‐rich fibrin alone or in combination with different biomaterials for the treatment of periodontal intra‐bony defect.MethodsUp to April 2022, Cochrane library, Medline, EMBASE, and Web of Science databases were searched for randomized clinical trials. The outcomes of interest were probing pocket depth reduction, clinical attachment level gain, bone gain, and bone defect depth reduction. Bayesian network meta‐analysis with 95% credible intervals was calculated.ResultsThirty‐eight studies with 1157 participants were included. Platelet‐rich fibrin alone or platelet‐rich fibrin +biomaterials showed a statistically significant difference when compared with open flap debridement (p < 0.05, low to high certainty evidence). Neither biomaterials alone nor platelet‐rich fibrin +biomaterials showed a statistically significant difference when compared to platelet‐rich fibrin alone (p > 0.05, very low to high certainty evidence). Platelet‐rich fibrin +biomaterials showed insignificant differences as compared to biomaterials alone (p > 0.05, very low to high certainty evidence). Allograft +collagen membrane ranked the best in probing pocket depth reduction while platelet‐rich fibrin +hydroxyapatite ranked the best in bone gain.ConclusionIt seems that (1) platelet‐rich fibrin with/without biomaterials were more effective than open flap debridement. (2) Platelet‐rich fibrin alone provides a comparable effect to biomaterials alone and platelet‐rich fibrin +biomaterials. (3) Platelet‐rich fibrin +biomaterials provide a comparable effect to biomaterials alone. Although allograft +collagen membrane and platelet‐rich fibrin +hydroxyapatite ranked the best in terms of probing pocket depth reduction and bone gain respectively, the difference between different regenerative therapies remains insignificant, and therefore, further studies are still needed to confirm these results.