bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ni- and Pd-Catalyzed Enantioselective 1,2-Dicarbofunctionalization of Alkenes
Authors: Kang Taeho , Apolinar Omar , Engle Keary M. 
Published: June 2023

AbstractCatalytic enantioselective 1,2-dicarbofunctionalization (1,2-DCF) of alkenes is a powerful transformation of growing importance in organic synthesis for constructing chiral building blocks, bioactive molecules, and agrochemicals. Both in a two- and three-component context, this family of reactions generates densely functionalized, structurally complex products in a single step. Across several distinct mechanistic pathways at play in these transformations with nickel or palladium catalysts, stereocontrol can be obtained through tailored chiral ligands. In this Review we discuss the various strategies, mechanisms, and catalysts that have been applied to achieve enantioinduction in alkene 1,2-DCF.1	Introduction2	Two-Component Enantioselective 1,2-DCF via Migratory Insertion3	Two-Component Enantioselective 1,2-DCF via Radical Capture4	Three-Component Enantioselective 1,2-DCF via Radical Capture5	Three-Component Enantioselective 1,2-DCF via Migratory Insertion6	Miscellaneous Mechanisms7	Conclusion
N-Functionalization of 1,2-Azaborines
Authors: Liu Shih-Yuan , Lee Hyelee , Alvarado Marisol , Ingram Sarah , Li Bo 
Published: June 2023

AbstractGeneral protocols for the N-functionalization of 1,2-azaborines with C(sp3), C(sp2), or C(sp) electrophiles are described. The syntheses of a new parental BN isostere of trans-stilbene and a BN isostere of a lisdexamfetamine derivative were accomplished with the developed methodology.
Dual Responses of Fluorescence and Circular Dichroism for Antibiotics by a Cationic Cage in Water
Authors: Dong Yunhong , Cheng Lin , Cao Liping , Duan Yanjuan , Xu Huiru , Dong Ruonan , Guo Baolin 
Published: June 2023

AbstractA tetraphenylethene (TPE)-based cationic cage (1) can form a 1:2 host–guest complex with antibiotics in water and imparts dual responses of fluorescence and circular dichroism (CD) to antibiotics based on the fluorescence and adaptive chiral conformation of the TPE units. Moreover, the host–guest complexes 1⊃(antibiotic)2 exhibited good antibacterial activity.
Lymphocytic Host Response and other Prognostic Factors in Early Stage Squamous Cell Carcinoma of Tongue: Retrospective Analysis from a Tertiary Cancer Center
Authors: Nagarajan Aswin Anapathoor , Rajaraman Swaminathan , Sundersingh Shirley , Thangarajan Rajkumar 
Published: June 2023

Introduction The tongue is the most common site of malignancy in the oral cavity, and squamous cell carcinoma is the commonest histology. The prognosis remains unfavorable despite treatment, resulting in higher mortality rates. Early stage carcinoma of the tongue is a distinct entity and is primarily treated with either surgery or radiotherapy. Various factors have been implicated in the prognosis of early stage tongue carcinomas. The main objective of this study is to access whether the lymphocytic host response (LHR) and other prognostic factors influence the survival.
Patients and Methods The data of 129 patients with Stage I and Stage II (T1-2, N0) tongue cancer treated in our institute from January 2012 to December 2016 were retrospectively abstracted from the hospital case records. The various clinical and pathological factors were recorded. The Kaplan–Meier model was used for survival analysis. The disease-free survival (DFS) and the overall survival (OS) with respect to stage and LHR were calculated.
Results On multivariate analysis, site of lesion, comorbidities, habits, grade of the tumor, perineural infiltration (PNI) did not influence the survival. The main factor which was found to be significant in DFS was LHR. The DFS was better for the patients who had lymphocytic infiltration of ≥ 70% (strong LHR) when compared with <70%(weak LHR) (p = 0.037). The OS with respect to stage (p = 0.608) and LHR (p = 0.164) was not found to be statistically significant.
Conclusion The patients with weak LHR had less DFS when compared with patients with strong LHR. Larger studies are needed to evaluate whether adding adjuvant therapy may benefit the patients with weak LHR in early stage tongue cancer.
Tumor-Induced Osteomalacia: A Case Report of Rare Disease and Literature review
Authors: Bansal Shivam , Maheshwari Vikas , Niraula Bishwa Bandhu , Regmi Anil , Sridharan Kalyani , Dhingra Mohit 
Published: June 2023

Background Oncogenic osteomalacia term used for tumor-induced osteomalacia (TIO) is a paraneoplastic syndrome of abnormal phosphate metabolism secondary to ectopic endocrine tumors. The diagnosis often becomes difficult due to rarity of occurrence and deficient literature. The reconstruction following resection has its own technical difficulties, which are addressed in this article.
Presentation of Case A 39-year-old female presented with pain in bilateral lower limbs and difficulty in mobilizing. The patient had unexplained hypophosphatemia which was diagnosed due to tumor (arising ectopically in greater trochanter), inducing osteomalacia. She was managed successfully with excision of tumor and reconstruction. The biochemical parameters improved drastically within 5 days and fracture healed in 6 weeks' time.
Conclusion TIO is a debilitating disease with significant morbidity due to prolonged onset to diagnosis interval and difficulty in localizing the causative tumor. So thorough clinico-radiological and laboratory parameter correlation is a necessity. A rapid diagnosis followed by complete surgical excision, which remains the gold standard treatment modality that confers favorable prognosis in most patients, with strict vigilance for recurrence is required.
Being human as praxis: for people with learning disabilities
Authors: Goodley Dan 
Published: June 2023

AbstractThe paper posits that being human as praxis—in relation to the lives of People with Learning Disabilities—offers a significant and original insight into critical and social theory across the social sciences and humanities. Drawing on postcolonial and critical disability theory I suggest that being human as praxis of People with Learning Disabilities is sophisticated and generative but is always enacted in a deeply disablist and ableist world. I explore being human as praxis in (i) a culture of disposability; (ii) the midst of absolute otherness and (iii) the confines of a neoliberal-ableist society. For each theme I start with a provocation, follow up with an exploration and end with a celebration (with the latter referencing the activism of people with learning disabilities). I conclude with some thoughts on simultaneously decolonising and depathologising knowledge production, the importance of recognition and writing for rather than with People with Learning Disabilities.
Techniques for overcoming difficult interdisciplinary dialogue in expert panels: lessons for interactional expertise
Authors: Caby Vincent 
Published: June 2023

AbstractWhich techniques and skills can be used to overcome the obstacle of dialogue between scientists in different disciplines? Drawing on Gorman’s book on trading zones and Collins and Evans’ thinking on interactional expertise, this article analyses the work by individuals to manage five interdisciplinary panels commissioned by French ministries. It observes that these panel managers have different techniques to open, construct and close the debate. These techniques, which condition the submission of the final report, call for skills that managers acquire over the course of their experiences in trading zones. Implications of findings for the formation and management of interdisciplinary expert groups and for the concept of interactional expertise are discussed.
Optoelectronic and thermoelectric properties of Sb2S3 under hydrostatic pressure for energy conversion
Authors: Azadparvar Maliheh , Rahnamaye Aliabad H. A. , Özdemir Evren G. 
Published: June 2023

This study reports the optoelectronic and thermoelectric properties of antimony trisulfide (Sb2S3) under a hydrostatic pressure of up to 20.4 GPa. The properties were computed based on the full-potential linearized augmented plane wave using the generalized gradient approximation by Perdew, Burke, and Ernzerhof as the exchange-correlation potentials. It was shown that increasing the pressure from 0.00 to 20.4 GPa decreases the calculated bandgap from 1.44 to 0.84 eV. There was a discontinuity in the pressure range of 4.82–6.3 GPa due to the isostructural electronic phase transition. The applied pressure increases the inner electrical polarization. At high pressure, the energy of the negative value of ε1 becomes large, and ε1 itself always remains negative. We observed that the high absorption of Sb2S3 also increases with pressure and the plasmon energy shifts to high energy. The applied pressure increases the static dielectric constant and static refractive index. It was found that the Seebeck coefficients increase with increasing temperature and decrease with increasing pressure. The bipolar effect occurs at low doping levels and high pressure. The optical and thermoelectric properties of Sb2S3 obtained under pressure show that it is suitable for clean energy conversion and optoelectronic applications.
Phosphorylation of DNA-PKcs at the S2056 cluster ensures efficient and productive lymphocyte development in XLF-deficient mice
Authors: Zhu Yimeng , Jiang Wenxia , Lee Brian J. , Li Angelina , Gershik Steven , Zha Shan 
Published: June 2023

The nonhomologous end-joining (NHEJ) pathway is a major DNA double-strand break repair pathway in mammals and is essential for lymphocyte development. Ku70 and Ku80 heterodimer (KU) initiates NHEJ, thereby recruiting and activating the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs). While DNA-PKcs deletion only moderately impairs end-ligation, the expression of kinase-dead DNA-PKcs completely abrogates NHEJ. Active DNA-PK phosphorylates DNA-PKcs at two clusters—PQR around S2056 (S2053 in mouse) and ABCDE around T2609. Alanine substitution at the S2056 cluster moderately compromises end-ligation on plasmid-based assays. But, mice carrying alanine substitution at all five serine residues within the S2056 cluster (

DNA-PKcs
PQR/PQR

) display no defect in lymphocyte development, leaving the physiological significance of S2056 cluster phosphorylation elusive. Xlf is a nonessential NHEJ factor.

Xlf
−/−

mice have substantial peripheral lymphocytes that are completely abolished by the loss of DNA-PKcs, the related ATM kinases, other chromatin-associated DNA damage response factors (e.g., 53BP1, MDC1, H2AX, and MRI), or RAG2-C-terminal regions, suggesting functional redundancy. While ATM inhibition does not further compromise end-ligation, here we show that in XLF-deficient background, DNA-PKcs S2056 cluster phosphorylation is critical for normal lymphocyte development. Chromosomal V(D)J recombination from

DNA-PKcs
PQR/PQR
Xlf
−/−

B cells is efficient but often has large deletions that jeopardize lymphocyte development. Class-switch recombination junctions from

DNA-PKcs
PQR/PQR
Xlf
−/−

mice are less efficient and the residual junctions display decreased fidelity and increased deletion. These findings establish a role for DNA-PKcs S2056 cluster phosphorylation in physiological chromosomal NHEJ, implying that S2056 cluster phosphorylation contributes to the synergy between XLF and DNA-PKcs in end-ligation.
Operando analysis reveals potential-driven in situ formation of single-Fe-atom electrocatalysts for green production of ammonia
Authors: Yang Fa , Song Ping , Ge Xin , Wang Yan , Gunji Takao , Zhang Wei , Zhao Xiao , Xu Weilin 
Published: June 2023

As a sustainable approach for N
2
fixation, electrocatalytic N
2
reduction reaction (N
2
RR) to produce ammonia (NH
3
) is highly desirable with a precise understanding to the structure-activity relationship of electrocatalysts. Here, firstly, we obtain a novel carbon-supported oxygen-coordinated single-Fe-atom catalyst for highly efficient production of ammonia from electrocatalytic N
2
RR. Based on such new type of N
2
RR electrocatalyst, by combining operando X-ray absorption spectra (XAS) with density function theory calculation, we reveal significantly that the as-prepared active coordination structure undergoes a potential-driven two-step restructuring, firstly from Fe
SA
O
4
(OH)
1a
to Fe
SA
O
4
(OH)
1a′
(OH)
1b
with the adsorption of another –OH on Fe
SA
at open-circuit potential (OCP) of 0.58 V
RHE
, and subsequently restructuring from Fe
SA
O
4
(OH)
1a′
(OH)
1b
to Fe
SA
O
3
(OH)
1a″
due to the breaking of one Fe-O bond and the dissociation of one –OH at working potentials for final electrocatalytic process of N
2
RR, thus revealing the first potential-induced in situ formation of the real electrocatalytic active sites to boost the conversion of N
2
to NH
3
. Moreover, the key intermediate of Fe-NNH
x
was detected experimentally by both
operando
XAS and in situ attenuated total reflection–surface-enhanced infrared absorption spectra (ATR-SEIRAS), indicating the alternating mechanism followed by N
2
RR on such catalyst. The results indicate the necessity of considering the potential-induced restructuring of the active sites on all kinds of electrocatalysts for such as highly efficient ammonia production from N
2
RR. It also paves a new way for a precise understanding to the structure-activity relationship of a catalyst and helps the design of highly efficient catalysts.
Prosodic marking of contrast in LSFB (French Belgian Sign Language)
Authors: Lombart Clara 
Published: June 2023

AbstractThis paper examines the relationships between information structure and prosody in LSFB (French Belgian Sign Language), focusing on the marking of contrast. A recurrent assertion in the literature is that contrast is always marked by prosodic prominence. We discuss this interaction at the manual level by investigating the connections between the presence or absence of a manual prosodic marker and the contrastive or non-contrastive character of a sign. To explore this connection, we examine data related to the holds, dominance reversals, repetitions, and variations in duration and displacement produced on 977 signs by four native LSFB signers. We also assign a certain degree of prominence to every sign depending on the number of cues employed by a participant. Data are analysed using descriptive and inferential statistics (Chi-squared test, Mann-Whitney U test, or Kruskal-Wallis test). The results show that contrast has its own prosodic marking at the manual level in LSFB and that contrastive signs are more prominent than non-contrastive ones. The prevailing cues used to encode contrast are variations in displacement or relative duration, and combinations of relative duration and displacement. The interactions between prosody, information structure, and articulatory constraints are discussed to explain the different patterns highlighted in the data sample.
Determining ideology through translation*
Authors: Kamyanets Angela 
Published: June 2023

Abstract
Based on the premise that journalistic translation functions as a gatekeeping force, this study uses Thematic
Content Analysis and Critical Discourse Analysis to analyse translation decisions of UNIAN, a leading news agency in Ukraine owned
by oligarch Ihor Kolomoisky, in order to ‘reconstruct’ its ideological agenda. The findings indicate that, as regards
international matters, the ideology promoted by UNIAN is oriented towards Ukrainian national interests. This conclusion follows
from the dominant themes of the translated articles – such as the Russian aggression in the east of Ukraine, Ukraine’s
relationship with the new US administration, and the EU’s attitude to Russia – and from ideological shifts in the target texts.
Domestically, however, UNIAN appears to be at least partially pro-oligarchic, since the corruption and reform theme is downplayed
in the translations, even though it was widely discussed in western press at the time when the corpus for the study was
collected.
Dual gradient method for ill-posed problems using multiple repeated measurement data
Authors: Jin Qinian , Wang Wei 
Published: June 2023

Abstract
We consider determining

-minimizing solutions of linear ill-posed problems

A
x
=
y

, where

A
:

X

→

Y

is a bounded linear operator from a Banach space

X

to a Hilbert space

Y

and

is a proper strongly convex penalty function. Assuming that multiple repeated independent identically distributed unbiased data of y are available, we consider a dual gradient method to reconstruct the

-minimizing solution using the average of these data. By terminating the method by either an a priori stopping rule or a statistical variant of the discrepancy principle, we provide the convergence analysis and derive convergence rates when the sought solution satisfies certain variational source conditions. Various numerical results are reported to test the performance of the method.
Losing the balance in risk-benefit analysis
Authors: Rehani Madan M 
Published: June 2023

Abstract
The idea of a benefit-risk analysis has been used for decades, but no one has probably bothered to see if there is a ratio or even questioned the concept because it does give an intuitive sense. There are situations where the tendency to lose the balance between the risk and benefit has been observed to move either towards benefit alone or risk alone. This may happen in medicine for benefit alone and in the nuclear industry for risk alone when public perceptions are involved. For example, in medicine, when the risk is uncertain and/or may happen in the long term as against the benefit, which may be immediate, the tendency to ignore risk has been observed. On the other hand, accidents in the nuclear industry shadow the benefits of nuclear power, resulting in authorities abandoning nuclear power in some countries. Similarly, tissue reactions to patients in fluoroscopic guided interventions have been highlighted despite the fact that the stochastic risks in the same procedure may be tens of times higher. Attention has been drawn to the analogy of risks in pharmaceuticals as against radiation and better-developed system for drugs for us to learn from. This article describes situations of losing balance and provides motivation for the International Commission on Radiological Protection to develop solutions for situations that entail immediate benefits with long-term radiation risk, commonly encountered in medical exposure.
Shape memory alloy based smart compression stocking and real-time health monitoring app for deep venous thrombosis
Authors: Hua Shuyuan , Liu Yiwen , Jiang Jinhua , Xiao Fei , Hou Ruihang , Li Aijia , Cai Xiaorong , Hu Xiangjun , Ding Xifan , Jin Xuejun 
Published: June 2023

Abstract
Deep venous thrombosis (DVT) is a severe venous disease with high incidence and mortality rate. Patients suffering from DVT have poor quality of life due to continuous sequela. Prophylaxis is applied on high-risk individuals while clinical researches have demonstrated the efficacy of graduated compression stockings (GCSs) in reducing DVT incidence. However, the prophylactic effect of conventional GCS on DVT in daily life does not meet the expectation due to its disadvantages such as low compliance and static pressure. For the purpose of superior prevention, a smart graduated compression stocking (SGCS) based on shape memory alloy (SMA) was designed, prototyped and tested in this research. A related mobile App was designed to modulate dynamic pressure and monitor health conditions such as temperature and pulse during the application of the SGCS. Experimental results showed that the prototype was able to provide clinical-standard pressure (at least 15 mmHg to 21 mmHg), three levels of adjustable dynamic pressure and low dressing difficulty while the App guaranteed the real-time physiological signs monitoring of skin temperature and dorsalis pedis artery pulse.
Deterministic all-versus-nothing proofs of Bell nonlocality based on non-stabilizer states
Authors: Tang Weidong 
Published: June 2023

Abstract
The all-versus-nothing proof of Bell nonlocality is a prominent demonstration of Bell’s theorem without inequalities. There are two kinds of such proofs: the deterministic all-versus-nothing proof and the probabilistic all-versus-nothing proof, which have received extensive research attention. Traditionally, all previous deterministic all-versus-nothing proofs are constructed based on stabilizer states. However, this work presents new deterministic proofs derived from non-stabilizer states, thereby breaking away from this conventional approach. These novel results not only significantly broaden the range of demonstrations of Bell nonlocality without inequalities but also offer valuable resources for certain quantum information processing applications.
Shimmering gravitons in the gamma-ray sky
Authors: Ramazanov S. , Samanta R. , Trenkler G. , Urban F. 
Published: June 2023

Abstract
What is the highest energy at which gravitons can be observed? We address this question by studying graviton-to-photon conversion — the inverse-Gertsenshtein effect — in the magnetic field of the Milky Way. We find that above ∼ 1 PeV the effective photon mass grows large enough to quench the conversion rate.
For sub-PeV energies, the induced photon flux is comparable to the sensitivity of LHAASO to a diffuse γ-ray background, but only for graviton abundances of order Ωgw
h
2
0 ∼ 1. In the future, owing to a better understanding of γ-ray backgrounds, larger effective areas and longer observation times, sub-PeV shimmering gravitons with a realistic abundance of Ωgw
h
2
0 ∼ 0.01 could be detected. We show how such a large abundance is achieved in a cosmologically-motivated scenario of post-recombination superheavy dark matter decay. Therefore, the sub-PeV range might be the ultimate energy frontier at which gravitons can be observed.
Research on General Structure of Double Returns Vertical Wind Tunnel
Authors: Shen Jiang , Zhang Yifei , Qiu Rongkai , YueyinMa  , Liu Bingbin 
Published: June 2023

Abstract
Vertical wind tunnels play very important role in parachute training, helicopter rotor test, flight experience and other aspects, among which the double returns vertical wind tunnel has spread widely due to its low lose and low running cost. By using innovative structure design and finite element method, the general layout, research on design of supports and important sections are completed. The design part mainly describes glass flight section, integrated fan section, wind speed adjust device, ventilation door and the whole raft foundation structure. The dynamic debugging results show that the double return vertical wind tunnel has rational design, little vibration and high efficiency.
Development of a Moving-Least-Square-based Immersed Boundary Method for the simulation of viscous Compressible Flows
Authors: Yi Hang , Wang Yan 
Published: June 2023

Abstract
In this paper, a Moving-Least-Squares (MLS)-based immersed boundary method (IBM) for simulating viscous compressible flows is proposed. For this method, the compressible lattice Boltzmann flux solver (LBFS) is used to solve the flow field on the Eulerian mesh and the MLS-based IBM introduced in present paper is used to implement boundary condition. The discrete Lagrangian points are used to represent the Solid boundaries. A second-order MLS interpolation is used for numerical exchange between two grids of IBM. The forced implicit boundary condition is adopted to ensure that the physical boundary condition can be accurately satisfied. The present method is able to achieve a higher numerical accuracy than traditional IBM, which use the Delta function for interpolation. Some numerical validation tests are used for the validation of proposed method. The order and accuracy of the MLS approximation are tested by using a classical example of flow past a cylinder. Test of flow past the NACA0012 airfoil at different Mach numbers, angles of attack and Reynolds numbers is applied to verified the accuracy.