bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of lightweight expanded clay aggregate as partial replacement of coarse aggregate on the mechanical properties of fire-exposed concrete
Authors: Abdullah Alaa H. , Mohammed Shatha D. 
Published: September 2023

Abstract
As aggregate material typically comprises 65–75% of concrete volume and has a significant effect on its mechanical properties, aggregate type considerably affects concrete behavior at high temperatures. In this study, 80 concrete cylinders and 60 cubes were cast to investigate the residual strength of normal concrete that contains lightweight expanded clay aggregate (LECA) with different volumetric replacement ratios (0, 10, 20, and 30%) of the coarse aggregate. After the fire flame exposure effect of steady-state temperatures (300, 400, 500, and 600°C), and a sudden cooling process, the mechanical tests (compressive strength, tensile strength, and modulus of elasticity; Ec), as well as mass loss and thermal conductivity, were carried out on the specimens. The results indicate that increasing the LECA content in the mixture leads to better strength retention after exposure to fire. After exposure to a steady-state temperature of 600°C, the amount of decrease in mass, residual compressive and tensile strengths, and the residual amount of Ec were 7.61, 7.5, 7.16, and 6.24%; 57.1, 66.8, 69.8, and 72.0%; 22.4, 32.7, 41.8, and 48.6%;, and 16.0, 22.3, 23.4, and 24.3%, respectively, for the considered volumetric replacement ratios of 0, 10, 20, and 30%. Also, the values of the thermal conductivity were 1.4889, 1.1667, 1.0912, and 1.0410 W/m K, respectively.
Congestion control analysis of optical packet switch for optical data center applications
Authors: Shukla Utkarsh , Singh Archana , Singhal Neeraj 
Published: September 2023

Abstract
Optical data centers serve as the backbone of modern networking, facilitating seamless connectivity for users across the globe. The connection between users and the optical data centers is established through various network topologies, which play a critical role in determining the traffic characteristics. The design and implementation of these network topologies, along with the assortment of applications hosted on optical data centers, significantly influence the flow of data within the network. The advent of cloud computing has further revolutionized optical data center operations, leading to the coexistence of a wide range of applications on different optical data center switches. As a result, the traffic characteristics observed on each optical data center switch vary significantly. This diversity in traffic patterns necessitates a comprehensive understanding of how data arrival is managed and handled by the networking infrastructure. In this paper, we explore the concept of a random traffic model for data arrival on Top of Rack (ToR) switches, which represent a crucial component of optical data center networking. In the modeling, small world model is considered. The effect of buffering and packet priorities is observed on traffic shaping. Finally, to evaluate the effectiveness of the traffic shaping techniques, we measure the packet loss performance of ToR switches and found to be as low as 10−4 even at the higher loads. Blocking performance provides valuable insights into how effectively the optical data center network manages incoming data and avoids congestion or bottlenecks.
Down-regulated Wnt7a and GPR124 in early-onset preeclampsia placentas reduce invasion and migration of trophoblast cells
Authors: Shen Yan , Cui Qingyu , Xiao Li , Wang Lifeng , Li Qianqian , Zhang Ruihong , Chen Zhaowen , Niu Jianmin 
Published: September 2023

Abstract

Objectives
Preeclampsia (PE) is a disease specific to pregnancy that causes 9–10 % of maternal deaths. Early-onset PE (<34 weeks’ gestation) is the most dangerous category of PE. Wnt7a and GPR124 (G protein-coupled receptor 124) are widely expressed in the human reproductive process. Especially during embryogenesis and tumorigenesis, Wnt7a plays a crucial role. However, few studies have examined the association between Wnt7a-GPR124 and early-onset PE. The aim of this study was to examine the significance of Wnt7a and GPR124 in early-onset PE as well as Wnt7a’s role in trophoblast cells.

Methods
Immunohistochemistry (IHC), real-time PCR, and western blotting (WB) were used to investigate Wnt7a and GPR124 expression in normal and early-onset PE placentas. Additionally, FACS, Transwell, and CCK-8 assays were used to diagnose Wnt7a involvement in migration, invasion, and proliferation.

Results
In the early-onset PE group, Wnt7a and GPR124 expression was significantly lower than in the normal group, especially in the area of syncytiotrophoblasts (STBs) and extravillous trophoblasts (EVTs). A negative correlation was found between Wnt7a RNA and GPR124 expression (r=−0.42, p<0.01). However, the Wnt7a RNA expression level was positive correlated with PE severity. In further cellular functional experiments, knockdown of Wnt7a inhibits HTR8/SVeno cells invasion and migration but has little effect on proliferation and apoptosis.

Conclusions
Through the Wnt pathway, Wnt7a regulates trophoblast cell invasion and migration, and may contribute to early-onset preeclampsia pathogenesis. A molecular level study of Wnt7a will be needed to find downstream proteins and mechanisms of interaction.
Physical and chemical properties of beads glasses
Authors: Zarkooshi Ahmad Abdulhasan , Kaleli Murat , Tuncel Nina , Akkurt Iskender 
Published: September 2023

Abstract
The chemical and physical characterization of glass beads in different sizes with diameters 3 mm, 4 mm, 5 mm and 6 mm, respectively, have been studied in this paper. The X-ray Diffraction (XRD) analysis exhibited that the structure of glass bead is amorphous, and the diffraction peaks for annealing sample 400 °C and 600 °C, respectively, are seen at 2θ values ranged (26.165°–29.47°). The Scanning Electron Microscopy (SEM) and chemical composition measurement by Energy Dispersive Spectrometer (EDS) system have been conducted; they exhibited that all the samples have the same smooth surface, and the chemical composition analysis showed that the weight percentage of oxygen and silicon were dominant elements in the main structure of glass beads as well as some other elements like Ca, Mg, and Na were observed.
Gigantic blue shift of two-photon–induced photoluminescence of interpenetrated metal–organic framework (MOF)
Authors: Chen Zhihui , Xu Defeng , Zhu Menglong , Wang Yueting , Feng Junfan , Shu Chuancun , Xiao Si , Meng Jianqiao , He Jun 
Published: September 2023

Abstract
As an important means of modern science and technology, multiphoton fluorescence plays an essential role in high-resolution imaging, photochemistry, micro- and nano-processing and clinical diagnosis. Multiphoton fluorescence usually shares the same radiative channel as its intrinsic fluorescence. Under multiphoton excitation, except for red shift fluorescence caused by the reabsorption effect, gigantic blue shift of multiphoton fluorescence is rarely reported. In this work, metal–organic frameworks (MOFs) with 7-fold and 8-fold interpenetration are successfully synthesized. The synthesized 8-fold interpenetrated MOFs show unexpectedly giant blue-shifted (∼40 nm) two-photon–induced fluorescence compared with its fluorescence emission. Specific optical selection rules lead to different final transition states in one-photon absorption and two-photon absorption. The density functional theory (DFT) and time-dependent density functional theory (TDDFT) simulations show that, under two-photon excitation, electrons and holes can be more delocalized, and intermolecular interactions mainly govern the emission process of 8-fold interpenetrated MOFs. Highly excited electronic states of the interpenetrated MOFs are effectively excited and emitted under two-photon excitation, thus generating the inevitable blue-shifted two-photon–induced fluorescence emission. Our work provides a guide for exploring the excitation mechanism of fluorescent MOFs and offers an access to a tunable all-optical single-crystal device.
The crystal structure of catena-[diaqua-(4-acetylphenoxyacetato-κ
2
O,O)-bis(4-acetylphenoxyacetato-κ
3
O,O:O)-dihydrate-lanthanum(III)]–4,4′-bipyridine (2/1), C35H35NO14La
Authors: Ying Liu , Xi-Hai Yan , Yuan-Fang Wang , Xi-Shi Tai 
Published: September 2023

Abstract
C35H35NO14La, triclinic,

P
‾

$\overline{P}$

1 (no. 2), a = 9.06760(10) Å, b = 13.6139(2) Å, c = 15.5964(2) Å, α = 115.2310(10)∘, ß = 97.4010(10)∘, γ = 95.4830(10)∘, V = 1702.65(4) Å3, Z = 2, R

gt
(F) = 0.0431, wR

ref
(F
2) = 0.1059, T = 296.13(10) K.
Nonlinear dynamic responses of ballasted railway tracks using concrete sleepers incorporated with reinforced fibres and pre-treated crumb rubber
Authors: Raj Anand , Ngamkhanong Chayut , Prasittisopin Lapyote , Kaewunruen Sakdirat 
Published: September 2023

Abstract
Damages on railway sleepers due to heavy impact loads induced by the movement of trains can be reduced by improving their impact resistance. Fibre-reinforced/pre-treated crumb rubber concrete sleepers (RCSs) have the potential to display significant impact resistance to withstand a high-magnitude impact load. The ideal proportions of pre-treated crumb rubber, steel fibres, and polypropylene fibres (PFs) can be identified based on the minimum cost-to-impact energy ratio after conducting a drop weight impact test on prisms. The numerical model developed to assess the behaviour of ballasted tracks has been validated using both simulation results and field measurements. Numerical studies have been conducted on ballasted rail tracks with steel and PF-reinforced/pre-treated RCSs using LS-DYNA software. Dynamic strain rate-dependent material parameters are introduced in the numerical simulations. The nonlinear effect of higher train speeds on dynamic track responses has been highlighted in this article. Although the static load-carrying capacity and modulus of elasticity of rubber concrete are low, their dynamic performance controls the track displacements from exceeding permissible limits. The outcome of this study will provide new insights into the effects of railway concrete sleepers incorporated with reinforced fibres and pre-treated crumb rubber on railway track performance in order to ensure safety and reliability before it is put into services.
Long non-coding RNA, FOXP4-AS1, acts as a novel biomarker of cancers
Authors: Yu Liang , Lu Juan 
Published: September 2023

Abstract
Long non-coding RNAs (lncRNAs) are a recently discovered class of non-coding RNAs with a length of more than 200 nucleotides. Dysregulation of lncRNAs has been implicated in the development and progression of various human diseases and has pivotal functions in diverse biological processes, like cell apoptosis, proliferation, migration, and invasion. LncRNAs are increasingly being identified as potential targets for clinical applications based on their functional mechanisms, which are gradually being elucidated. One such disease-related lncRNA is the forkhead box P4-AS1 (FOXP4-AS1), which is abnormally expressed in multiple human diseases, including cancer and non-cancerous diseases. Moreover, FOXP4-AS1’s expression is linked with the clinical characteristics of patients. Mechanistically, FOXP4-AS1 mediates several cellular processes mainly through its target genes. Therefore, FOXP4-AS1 has been extensively investigated for its diagnostic, prognostic, and therapeutic potential. In this review, we discuss the expression patterns, major role, and molecular mechanisms of FOXP4-AS1, along with its association with clinical features and potential applications in clinical settings.
Salzburgs tränenreiche Urgeschichte – Bernstein als Medium sozialer und kultureller Interaktion
Authors: Wendling Holger 
Published: September 2023

Zusammenfassung
Bernstein besitzt als fossiles Baumharz aufgrund seiner spezifischen physischen Eigenschaften eine Aura, die ihn bis heute gleichermaßen als Schmuckstein und magisch-religiöses Amulett begehrt machte. Die überregionale, im antiken Sinne ‚globale‘ Verbreitung des baltischen Succinits findet ihren Niederschlag auch in den Ostalpen. Besonders der zentrale Kommunikationskorridor entlang der Salzach und des anschließenden Tauerntransits besticht während aller Epochen durch eine hohe Dichte von Bernsteinobjekten. Die Region dient deshalb als Modellfall zur Untersuchung zeitlich variabler Aspekte der Aneignung, Nutzung, ideellen Bedeutung und Verbreitung des Bernsteins.
Neben sehr seltenen bronzezeitlichen Objekten und einer häufigeren Verwendung in der frühen Eisenzeit ist der Dürrnberg bei Hallein neben dem benachbarten Salzrevier von Hallstatt einer der europäischen Schwerpunkte der Bernsteinnutzung während der Späthallstatt- und Frühlatènezeit. Hier liefern neue quantitative und qualitative Analysen Indizien für sich wandelnde Muster in Trageweise, Nutzung und symbolisch-magischer Bedeutung von Bernsteinschmuck. In der jüngeren Latènezeit kommt es regional und in weiteren Bereichen Europas zu einem graduellen Rückgang der Bernsteinnutzung. Er setzt sich in der römischen Kaiserzeit im Gebiet des municipium Claudium Iuvavum fort, bevor ein letztes Aufleben des Bernsteinschmucks im Frühmittelalter einsetzte.
In diachroner Perspektive werden zeitspezifische Muster in der Verwendung und Integration des fremdartigen Rohstoffes in die indigene materielle Kultur und magische Vorstellungswelt deutlich. Bernstein erscheint allerdings nicht nur als ‚Beiprodukt‘ rein ökonomischer Kommunikation entlang transregionaler Handels- und Verkehrsbeziehungen der sogenannten ‚Bernsteinstraßen‘. Vielmehr zeigen qualitative und quantitative Analysen, dass der Bernstein zu unterschiedlichen Zeiten bewusst als Medium sozialer Kommunikation gewählt oder verworfen sowie inhaltlich mit konkreten Bedeutungen belegt wurde. In Prozessen intentioneller kultureller Aneignung offenbart das exotische Material damit die differenzierte Entscheidungs- und Handlungskompetenz indigener Gemeinschaften der mitteleuropäischen Ur- und Frühgeschichte.
Some remarks on studies of Prehistoric craft production from the perspective of Gottfried Semper’s ideas
Authors: Palaguta Ilia 
Published: September 2023

Abstract
The approach developed by Gottfried Semper in the mid-19th century seems to be quite productive for studying the evolution of forms and decoration of objects of material culture. Based on the relationship between the properties of materials and technologies, it formed the basis of modern design practices. The use of this approach makes it possible to explain many phenomena, particularly, the emergence of skeuomorphic forms of ornament (so-called ‘technical ornament’), and also to expand our understanding of materials and technologies that have not reached our time. The reconstruction of non-preserved elements of culture can be complemented by studies on their visual representation in fine art. The principle of development of material culture can also be represented as a movement from the archetype to the material embodiment of ideas, which is possible at the corresponding level of technological development.
The potential effect of walking on quantitative sensory testing, pain catastrophizing, and perceived stress: an exploratory study
Authors: Rasmussen Anna Houmøller , Petersen Lærke Kjeldgaard , Kaasgaard Sperling Mette , Bertelsen Maria Møller , Rathleff Michael Skovdal , Petersen Kristian Kjær-Staal 
Published: September 2023

Abstract

Objectives
Studies suggest that a range of pain mechanisms, such as poor quality of sleep, perceived stress, pain catastrophizing or pain sensitivity, are likely to enhance clinical pain. Animal studies suggest that these pain mechanisms can be modulated by increasing physical activity, but human data are needed to support this hypothesis. This exploratory study aimed to investigate the changes in pain mechanisms after a simple self-directed walking program of 8-weeks. Additionally, this exploratory study investigated the interaction between changes over time in assessments of poor quality of sleep, perceived stress, pain catastrophizing or pain sensitivity and how these changes interacted with each other.

Methods
This prospective cohort study included 30 healthy subjects who were assessed at baseline and 4- and 8-weeks after initiating the walking program (30 min walking/day for 8 weeks). Self-report outcomes included: Pain Catastrophizing Scale (PCS), the Perceived Stress Scale (PSS) and Pittsburgh Sleep Quality Index. Pressure pain thresholds, temporal summation of pain and conditioned pain modulation (CPM) were assessed using cuff algometry.

Results
Twenty-four subjects completed all the visits (age: 42.2, SD: 14.9, 16 females). PCS and PSS significantly decreased at the 8-week’s visit compared to baseline (p<0.05). No significant differences were seen for an improvement in quality of sleep (p=0.071) and pain sensitivity (p>0.075) when comparing the 8-week’s visit to the baseline visit. Changes in pain mechanisms comparing baseline and 8-weeks data were calculated and regression analyses found that an improvement in PCS was associated with an improvement in CPM (R2=0.197, p=0.017) and that a higher adherence to the walking program was associated with a larger improvement in PCS (R2=0.216, p=0.013).

Conclusions
The current exploratory study indicates that a simple self-directed walking program of 8-weeks can improve pain catastrophizing thoughts, perceived stress. Higher adherence to the walking program were associated with an improvement in pain catastrophizing and an improvement in pain catastrophizing was associated with an increase in conditioned pain modulation.
ROTA DE INTEGRAÇÃO LATINO AMERICANA: A IMPORTÂNCIA DA GOVERNANÇA CORPORATIVA NO DESENVOLVIMENTO EMPRESARIAL SUL-MATO-GROSSENSE
Authors: Bastos Beatriz Silva , Salazar Milena Barbosa , Shiota Hanae Caroline Quintana , Dorsa Arlinda Cantero 
Published: September 2023

É importante destacar que há a necessidade imperiosa de as empresas atuarem de forma responsável e cidadã, não se limitando apenas aos cuidados previstos com relação às licenças previstas em órgãos regulatórios para seu funcionamento, como também em se preocupar com todos os agentes que estiverem envolvidos ou interessados nas atividades. Sobre esta temática, este artigo discute a importância da governança corporativa no desenvolvimento empresarial sul-mato-grossense com vistas à implantação da Rota Bioceânica. Para tanto, objetiva-se um panorama sobre conhecimento em governança corporativa a fim de influenciar os mais diversos agentes na adoção das melhores práticas, contribuindo para o desempenho sustentável das organizações e, consequentemente, para uma sociedade melhor; e, que possam servir de subsídios teóricos para a implantação da Rota. Neste contexto, esta pesquisa em andamento aborda a esfera de atuação das organizações no mundo atual, sendo relevante destacar o aumento significativo dos desafios sociais e ambientais sejam eles globais, regionais ou locais. Desta forma, pretende-se realizar uma pesquisa exploratória, bibliográfica e documental a partir de uma abordagem qualitativa do material encontrado. Importante salientar que esta pesquisa relaciona-se ao Observatório interdisciplinar ligado à Universidade Católica Dom Bosco e à Rede de Pesquisas de Universidades – UniRila e tem como focalização oferecer um espaço de estudo, pesquisa, organização, difusão de conhecimentos e aplicação dos mais distintos temas a fim de oferecer substratos às ações de interesse público e privado, com vistas à implantação da Rota Bioceânica. Como resultados preliminares, é de suma importância que o estado do MS esteja preparado para uma gestão corporativa e assim possibilitar a estimulação do comércio regional, o aprofundamento das relações de integração entre os quatro países e o fomento do turismo cultural.
Selected Determinants of the Quality of Life of Patients with Degenerative Changes of the Spine
Authors: Krzemińska Sylwia , Nowak Agnieszka , Borodzicz Adriana , Bąk Ewelina , Kostka Anna 
Published: September 2023

Introduction. Degenerative spinal disease is considered one of the most prevalent chronic diseases in Poland and worldwide. Sedentary lifestyle, lack of physical activity, and spinal overload contribute to this state of affairs. The chronic nature of the disease, along with pain and functional limitations of the musculoskeletal system, impact the quality of life.
Aim. To determine the level of life quality and factors influencing the quality of life in patients with degenerative spinal changes.
Material and Methods. The study involved 107 individuals aged between 55 and 65 years. Standardized research tools were utilized, including the Acceptance of Illness Scale (AIS), Oswestry Disability Index (ODI), Neck Disability Index (NDI), Activities of Daily Living scale (ADL), and the World Health Organization Quality of Life-Bref (WHOQoL-BREF) questionnaire.
Results. The level of illness acceptance in the study population was 26.52 points (SD=6.61). All respondents experienced pain symptoms, with an average pain intensity of 7.02 (SD=1.13). The average self-assessed quality of life among the participants was 3.5 points (SD=0.76), while the average self-assessed health rating was 2.54 points (SD=0.7). Spinal disability affected all patients in the lumbar region, whereas no disability was reported in the cervical region by 27.10% of the respondents.
Conclusions. Patients with degenerative spinal changes have a relatively good quality of life and a moderate level of illness acceptance. Age, marital status, occupational activity, body mass, pain intensity, and degree of disability all influence the quality of life. (JNNN 2023;12(1):44–52)
Food Restriction Level and Reinforcement Schedule Differentially Influence Behavior during Acquisition and Devaluation Procedures in Mice
Authors: Chevée Maxime , Kim Courtney J. , Crow Nevin , Follman Emma G. , Leonard Michael Z. , Calipari Erin S. 
Published: September 2023

AbstractBehavioral strategies are often classified based on whether reinforcer value controls reinforcement. Value-sensitive behaviors, in which animals update their actions when reinforcer value is changed, are classified as goal-directed; conversely, value-insensitive actions, where behavior remains consistent when the reinforcer is removed or devalued, are considered habitual. Basic reinforcement schedules can help to bias behavior toward either process: random ratio (RR) schedules are thought to promote the formation of goal-directed behaviors while random intervals (RIs) promote habitual control. However, how the schedule-specific features of these tasks interact with other factors that influence learning to control behavior has not been well characterized. Using male and female mice, we asked how distinct food restriction levels, a strategy often used to increase task engagement, interact with RR and RI schedules to control performance during task acquisition and devaluation procedures. We determined that food restriction level has a stronger effect on the behavior of mice following RR schedules compared with RI schedules, and that it promotes a decrease in response rate during devaluation procedures that is best explained by the effects of extinction rather than devaluation. Surprisingly, food restriction accelerated the decrease in response rates observed following devaluation across sequential extinction sessions, but not within a single session. Our results support the idea that the relationships between schedules and behavioral control strategies are not clear-cut and suggest that an animal’s engagement in a task must be accounted for, together with the structure of reinforcement schedules, to appropriately interpret the cognitive underpinnings of behavior.