bluuebunny/crossref_metadata_2025_split huggingface dataset:
HBs Antigen Seroprevalence of the Hepatitis B Virus in Blood Donors using Enzyme Linked Immunosorbent Assay at the Essos Hospital Centre of Yaounde, Cameroon
Authors: Olinga Zanga , Philippe Salomon Nguwoh  , Taheu Christian Ngounouh , Likeng Julienne Louise Ngo , Nguepidjo Gilbert , Tonmeu Sandrine Chimène Douyong , Folefack Guy Benoit Lekeufack , Sevilor Kekeunou , Tchoffo Désiré , Fokam Joseph 
Published: December 2022

Background: Hepatitis B virus (HBV) is one of the most common infectious pathogens worldwide particularly in sub Saharan African (SSA). In Cameroon, HBV is highly endemic (HBsAg >8%), suggesting a rigorous transfusion safety policy on the national territory. This study aimed to determine HBs antigen (HBsAg) seroprevalence of the HBV in blood donors using Enzyme Linked Immunosorbent (ELISA) at the Essos Hospital Centre (EHC) in Yaounde, Cameroon.
Methods: From January, 18th to May 31st, 2021, we carried out a quantitative, cross-sectional and descriptive study among 326 volunteer blood donors attending EHC of Yaounde, Cameroon. The socio-demographic data of the participants was described while the surface antigen of hepatitis B virus (HBsAg) was determined using qualitative ELISA (Rapid Labs HBsAg) technique in the sera or plasma. The data was analyzed using the IBM Statistical Package for the Social Sciences (SPSS) v. 22. The difference between two proportions was considered significant when the probability of error was less than 0.05 (p<0.05).
Results: The median age of blood donors was 25 years (min-max: 12-52 years), the male were more represented with 96.32% (314/326) and the sex ratio (M/F) was 26.2. Globally, the HBsAg seroprevalence among blood donors was 13.19% (95% CI: 9.7%-17.4%; 43/326). The seroprevalence of HBV (HBsAg) was not statistically associated with sociodemographic characteristics of the study population (p<0.05). Meanwhile, this seroprevalence was high in male (95.35%; n=41), in the blood donors aged between 18 and 26 years old (51.16%; n=22), in single (83.72%; n=36) in blood donors with secondary education (74.42%; n=32). In addition, informal (55.81%; n=24), catholic (100.0%) and family blood donors (100.0%) were more infected.
Conclusion: This study revealed a very high HBs antigen seroprevalence in blood donors attending the EHC in Yaounde, Cameroon. However, none of the sociodemographic characteristics was not significantly associated with HBV infection in the study population. Thus, reducing the frequency of post-transfusion hepatitis B remains a permanent challenge in Cameroon.
A Prospective Observational Study on Evaluating the Efficacy of Bedside Optic Nerve Sheath Diameter in Assessing Clinical Progression of Patients Admitted in Neurosurgical ICU with Comparisons to CT Scans and GCS Score
Authors: Munakomi Sunil , Chaulagain Dipak 
Published: December 2022

Background: Ultrasound Optic nerve sheath diameter ultrasound (ONSD) assessment is a non-invasive, bedside, and easily repeatable tool for dynamic measurement of intracranial pressure with high diagnostic accuracy. The goal of this study was to find out if an ONSD can accurately predict the findings of the progression of intracranial lesions in computed tomography (CT) scans and associated deterioration in Glasgow Coma Scale (GCS) among neurosurgical patients.
Methods: We conducted a prospective analysis of ONSD assessment among 54 patients admitted to neurosurgical intensive care unit for clinical and radiological evaluation of raised intracranial pressure. Both horizontal and vertical optic nerve sheath diameters were measured 3 mm beneath the globe in each eye using a 7.5-10MHz ultrasonography probe. A binocular change in optic nerve sheath diameter of more than 2.00 mm in two consecutive readings in the same patient was deemed abnormal. The accuracy of ONSD was correlated with the concurrent neurological deterioration in the GCS and the progression of lesions in the CT images.

Results: When compared to CT scan progression, ONSD assessment had 86.7% sensitivity and 89.7% specificity for detecting elevated ICP. The Receiver operating curve (ROC) for the change in ONSD had a high ability to predict progression in ICP with the area under curve (AUC) value of 0.882. The drop in GCS with respect to CT progression of lesions has an AUC value of 0.849. The drop in GCS while compared to progressive lesions in CT images had a positive predictive value of 80% and the negative predictive value of 89.7% respectively.

Conclusions: The sensitivity, specificity, and positive predictive value of bedside ONSD ultrasonography in predicting raised intracranial pressure are significant when compared to the progression of lesions in CT images and concurrent drop in GCS. A bedside ONSD measurement is therefore a reliable armamentarium to predict elevated ICP since it is cheap, non-invasive, and repeatable.
Decreased IL-6 Levels more than 9,46 pg/ml and TNF-α Levels more than 14,43 pg/ml as Predictors of Functional Outcome of Oxford Knee Score 6 Weeks Post Total Knee Arthroplasty in Kellgren-Lawrence Grade IV Osteoarthritis Patients
Authors: Maha Putra Agung Gde Duta , Suyasa I Ketut , Karna Made Bramantya 
Published: December 2022

Introduction: Knee osteoarthritis (OA) occurs when there is a disruption of the dynamic balance between degradation and tissue synthesis. Operative management with Total Knee Artrhoplasty (TKA) is considered a late-stage therapeutic option. One of the reasons for the TKA is to reduce pain and improve knee movement function. However, the research has not extensively covered the impact of these proinflammatory cytokines and mechanical variables that emerge after the surgery and it is still unclear how they relate to post-TKA outcomes. This study aims to further prove the relationship between the magnitude of the decrease in inflammatory markers IL-6 and TNF-α with the functional output of post-TKA as measured by the Oxford Knee Score.

Methods: This investigation is a retrospective cohort. With a total of 28 patients of grade IV Knee OA based on Kellgren-Lawrence Classification who were candidates for TKA surgery between January 2022 until April 2022. Blood samples were obtained the day before surgery and six weeks thereafter. The Oxford Knee Score (OKS) was used to evaluate the patient’s functional status after surgery. Subjects were divided into two groups depending on whether or not they had reduced IL-6 and TNF-α levels to below the cut-off point by 6 weeks postoperatively, as calculated using ROC analysis. Chi-square tests were used to demonstrate the test's validity, and Pearson correlation test is also performed.

Results: Average difference in TNF-α levels was 20.19 (CI = 8.58564-31.81007), which is statistically significant at the 0.002 level (p 0.05), according to the findings of a paired t-test. When comparing IL-6 levels using a paired t-test, a mean difference of 10.52 (IC = 3.32833-17.70738) was found, which is statistically significant at the 0.002 level (p 0.05). TNF-α levels were considered to have been reduced at a cut off value of 14.43 pg/mL with an AUC of 0.837. As for IL-6, the threshold for a reduced level was 9.46 pg/mL with an AUC of 0.837. OKS was also associated with a 6.0-fold lower relative risk between lowered TNF-α and IL-6 levels.

Conclusion: There is a positive link between OKS and the reduction in IL-6 and TNF-α serum levels that occurs 6 weeks after surgery. Decreased level of serum IL-6 more than 9,56 pg/mL and TNF- α more than 14,43 pg/mL can be used as a predictor of good OKS after 6 weeks post TKA.
The Pattern of Chromosome Aberrations and Molecular Markers in the Population of Hematological Patients Diagnosed at the University Clinical Center Tuzla
Authors: Mešanović Semir , Perić Milan , Vareškić Aneta , Jahić Azra 
Published: December 2022

Introduction: Besides cardiovascular, malignant diseases are one of the leading causes of death in Bosnia and Herzegovina. At the top of this list are hematological diseases. This research aimed to identify cytogenetic and molecular biomarkers in patients treated for different types of hematological neoplasms. Methods: The retrospective study included 1600 samples of patients with different hematological diseases in the period from January 2006 to May 2022. The Polymerase Chain Reaction (RT-PCR) method was used to determine the presence of genetic rearrangements and to confirm the findings of conventional cytogenetic analysis. Results: Chromosomal aberrations were found in 739 (46,18%) patients. Using the RT-PCR technique, positive cases were increased by 1,5%. The BCR-ABL fusion gene was present in e14-a2 transcript form in 73% of samples, e13-a2 isoform in 21%, e1-a2 in 2%, while e14-a2/e1-a2 transcript coexpression was present in a percentage of 4% of the samples. The PML-RARa fusion gene was found in the form of bcr 1 transcripts in 21%, bcr2 32% and bcr3 59% of the samples. In twelve cases A type of the CBFB-MYH11 fusion transcript was detected. The MLL-AF4 fusion was found in only one case. Conclusion: The obtained percentages of frequency of individual molecular gene isoforms are in accordance with the results of most other researchers. This refers to the Balkan population and the Caucasian ethnic group.
IMPEMENTASI MEDIA RUBAR UNTUK MENINGKATKAN KEMAMPUAN KOGNITIF PADA ANAK KELOMPOK B DI TK BINA KALAM
Authors: Taufiq Linda Wati 
Published: December 2022

Pendidikan anak usia dini adalah pendidikan anak yang di selenggarakan sebelum jenjang pendidikan dasar yang dapat di selenggarakan melalui jalur pendidikan formal, non formal maupun informal. Dimana anak pendidikan usia dini yang di mulai dari usia 0-6 tahun yang dilakukan dengan pemberian stimulus atau rangsaangan pendidikan agar membantu pertunbuhan dan perkembangannya bagaimanakan dampak implementasi media rubar untuk meningkatkan kemampuan kognitif pada anak kelompok B di TK Bina Kalam. Dalam penelitian ini peneliti menggunakan metode penelitian deskriptif kualitatif dengan subjek penelitian peserta didik kelompok B di TK Bina Kalam sebanyak 12 siswa adapun tujuan penetilian ini adalah untuk membantu daya imajinasi dan pengetahuan di TK Bina Kalam. Implementasi media rubar melalui kegiatan menjari jejak, mengelompokkan dan berhitung menggunakn simbol. Adapun dampak dari media rubar dapat memberikan pembelajaran yang menyenangkan bagi anak.Serta dapat merangsang dan menstimulus terhadap kemampuan kognitif anak.
Meningkatkan Kemampuan Kognitif Melalui Kegiatan Mencampur Warna Menggunakan Media Pewarna Di Tk Negeri Pembina Kecamatan Padang Hilir Kota Tebing Tinggi
Authors: Supartik Supartik 
Published: December 2022

Penelitian tindakan kelas ini bertujuan untuk meningkatkan kemampuan kognitif melalui kegiatan mencampur warna menggunakan media pewrana. Subjek dalam penelitian tindakan kelas ini adalah anak taman kanak – kanat kelompk B.1 yang berjumlah 15 orang terdiri dari 9 anak perempuan dan 6 anak laki-laki. Tehnik pengumpulan data adalah dengan menggunakan data kuantitatif berupa tes dan data kualitatif berupa observasi. Hasil observasi menunjukan bahwa siklus I guru (peneliti) sudah dapat meningkatkan kemampuan kognitif anak dengan capaian (43%) dan pada siklus II kemapuan kognitif dapat meningkat dengan sangat baik (88%).
Penerapan Permainan Tradisional Jekka Ka’daro dalam Meningkatkan Perkembangan Motorik Kasar Anak Usia 5-6 Tahun
Authors: Aslinda Aslinda , Damayanti Eka , Khusyairy Umi 
Published: December 2022

Penelitian ini bertujuan untuk mengetahui untuk mengetahui gambaran penerapan permainan tradisional jekka ka’daro dalam meningkatkan perkembangan motorik kasar pada anak usia 5-6 tahun di Lemosusu Kelurahan Limboro Kecamatan Limboro Kabupaten Polewali Mandar selama masa pandemi covid-19. Metode penelitian menggunakan penelitian kuantitatif deskriptif. Teknik pengambilan sampel menggunakan sampel jenuh atau sensus dengan populasi berjumlah 10 anak yang berusia 5-6 tahun yang bertempat tinggal di Lemosusu Kelurahan Limboro Kecamatan Limboro Kabupaten Polewali Mandar. Instrumen penelitian menggunakan pedoman observasi. Teknik analisis data menggunakan statistik deskriptif. Hasil analisis deskriptif menunjukkan terjadinya peningkatan nilai rata-rata perkembangan motorik kasar dari sebelum perlakuan (pre-test) ke setelah perlakuan (post-test) permainan tradisional jekka ka’daro yakni sebesar 28,8. Dapat disimpulkan bahwa permainan tradisional jekka ka’daro dapat membantu meningkatkan perkembangan motorik kasar pada anak usia 5-6 tahun di Lemosusu Kelurahan Limboro Kecamatan Limboro Kabupaten Polewali Mandar selama masa pandemi covid-19.
Alman Gümrük Birliği (Zollverein) ve Osmanlı İmparatorluğu’yla İlişkileri
Authors: ÇITIR Burak 
Published: December 2022

Alman coğrafyasında bir serbest ticari bölge yaratma fikri, bu düşüncenin en aktif savunucusu olan Friedrich List gibi ekonomistlerle 19. yüzyılın başlarında büyük bir ivme kazanmıştır. Prusya, 1818’de tüm iç gümrük vergilerini ortadan kaldıran tarifesiyle serbest ticaret yapma fikrini komşu devletlere açmıştır. On yıl sonra Prusya ve Hessen-Darmstadt arasında ilk anlaşma imzalanırken aynı yıl, 1828’de Bavyera ve Württemberg arasında da bir gümrük birliği kurulmuştur. Her iki gümrük birliğine karşı yine aynı yıl içerisinde Hannover öncülüğünde Mitteldeutscher Handelsverein adında bir ticaret birliği de oluşturulmuştur. 1834’e gelindiğindeyse artık bu gümrük ve ticaret birliklerine dahil olan devletler Prusya’nın öncülüğünde bir gümrük birliği etrafında toplanmaya başlamıştır. Zollverein olarak adlandırılan Alman Gümrük Birliği, Alman İmparatorluğu’nun kuruluşundan on yedi yıl sonra 1888’de Hamburg ve Bremen’in de dahil olmasıyla tüm Alman coğrafyasını kapsar hale gelmiştir.
Bu çalışma, Türkçe literatürde müstakil bir literatürün oluşmadığı Zollverein’in kuruluş süreci ve sonrasında Alman coğrafyasında yaşananların yanı sıra çevre ülkelerle ilişkilerine de değinerek alana katkıda bulunmayı amaçlamaktadır.
Methodological Analysis of Strategies and Tactics in Literary Discourse
Authors: PRIHODKO Ganna , PRYKHODCHENKO Oleksandra , MOROSHKINA Halyna , ZALUZHNA Maryna , MERKULOVA Oksana 
Published: December 2022

The objective of this paper is analysis of the prevalent strategies and tactics of evaluation used in the literary discourse. Evaluation is regarded as a cognitive-communica­tive phenomenon. It is viewed as the essential part of human comprehension and reflection of the outer reality. The pragmatic aspect of strategies and tactics is considered as the major means of expressing the author’s intention and the goal. All evaluation strategies and tactics used in the literary discourse are divided into two groups: semantic and pragmatic. The semantic strategies consist of the persuasion strategy and the discrediting strategy, and the pragmatic ones contain the emotive-tuning strategies and the self-presentation strategy.
The results achieved confirm the idea that strategies and tactics of evaluation must undergo profound and detailed analysis in order to reveal the complex process of communication in the literary discourse.
The Philosophy of External Public Debt Management
Authors: MATEVOSYAN Ashot , GRIGORYAN Ani 
Published: December 2022

The main goal of the presented article is to propose effective solutions in the philosophical context of the management of the foreign public debt of RA. The Government of the RA should adopt as a priority the philosophy of attracting borrowed funds from the domestic market.
Considering also the fact that the Republic of Armenia relied on the philosophy of ensuring double-digit economic growth, having a long-term goal to increase the real GDP indicator, which will ultimately contribute to reducing the volume of debt obligations. As a priority contributing to this goal, the RA Government intends to significantly increase the volume of trade turnover[1], especially in connection with the current geopolitical situation, when Armenia, in particular, is the “gateway of Europe” for Russia, which is the main trading partner.
[1] In 2021, major trading partners of the RA included Russia from the CIS countries (31.4% of trade turnover, compared to 30.6% of the previous year), and from the EU and other countries China (15% and 13.5%, respectively), Iran (6.0% and 5.6 %), Switzerland (4.6% and 6.6%), Germany (3.5% and 4.2%), Italy (3.4% and 3.3%), Bulgaria (2.7% and 2.4%) and the Netherlands (2.7% and 1.8%). Source: RA Ministry of Finance www.minfin.am.
Determinanst of A Customer’s Decision to Choose A Murabaha Contract at Indonesian Sharia Bank
Authors: Kartika Puji Sri 
Published: December 2022

This study aims to analyze the determinants of customers in choosing a murabahah contract at an Islamic bank. This type of research is research quantitatively with a population of all BSI KCP Palopo Ratulangi customers. Taking a sample of 80 respondents using Roscoe's theory and using purposive sampling. The method used to test the hypothesis is the classical assumption test,hypothesis testing, multiple regression testing, and test of the coefficient of determination. The analytical tool in this study uses assistance SPSS versions 22 and 24. From the results of data processing it shows that simultaneously variable internal factors (psychological and personal) and variables external factors (culture and demography) have a positive and significant effect on the customer's decision in choosing a murabahah contract at an Islamic bank with a significance level of 0.000. While partially variable factor internal (psychological and personal) positive and significant effect on the customer's decision in choosing a murabahah contract at an Islamic bank with significance level of 0.004 and the value of tcount>ttable (3.823>1.991), but the variable external factors (culture and demographics) have no positive and significant effect on the customer's decision in choosing a murabahah contract at an Islamic bank with a significance level of 0.21 and tcount<ttable (1.245<1.991).
Pengaruh Corporate Identity terhadap Keputusan Menggunakan Produk Simpanan Mudharabah Khusus Pelajar di Baitul Maal Wat Tamwil (BMT) Madani
Authors: Ningsih Fitriyah , Prabowo Prayudi Setiawan 
Published: December 2022

The purpose of this study was to analyze whether there is an influence between Corporate Identity on the decision to use mudharabah savings products specifically for students in BMT Madani Sepanjang, Sidoarjo. This type of research is associative quantitative. The population used as many as 400 people, while the sample used as many as 200, the determination of the data using the Non Probability Sampling technique. The data collection method using interview, observation and questionnaire. The data analysis method uses simple linear analysis. The results obtained indicate that there is a positive and significant influence between Corporate Identity on the decision to use mudharabah savings products specifically for students. The influence of the Corporate Identity variable on the decision variable is 36.8%, while 63.2% is influenced by other variables.
Medication Related Osteonecrosis of the Jaw (MRONJ). Review and recent advances
Authors: Galiti Dimitra , Karayianni Aikaterini , Tsiklakis Kostas , Psyrri Amanda 
Published: December 2022

Abstract
Medication-Related Osteonecrosis of the Jaw (MRONJ) is defined as a complication, which affects the jawbone of patients that meet all of the following criteria: (a) patients were in the past or are now on treatment with bone targeting agents (BTAs) and/or antiangiogenics, (b) they have exposed bone or bone that can be probed through an intraoral or extraoral fistula for more than 8 weeks, and (c) they have no history of radiotherapy or obvious metastatic disease to the jaws.
Since the first reports, in 2003, plethora of articles on MRONJ significantly increased our knowledge of this potentially serious complication. However, controversies about the definition and clinical presentation, risk factors, radiological findings, staging and early diagnosis, prevention and treatment may affect the successful management and the quality of life of cancer patients. The purpose of this article is to present the current knowledge about MRONJ and the recent advances to best clinical practice and treatment.
Important questions will be discussed, including the following: (1) Should we wait for 8 weeks when a patient on antiresorptive therapy, presents with exposed necrotic jawbone? (2) Can we exclude the diagnosis of osteonecrosis if a patient presents without exposed bone? (3) Is the dental extraction a risk factor for MRONJ? (4) Should we perform the dental extraction, when a patient on antiresorptives, presents with a symptomatic tooth? (5) What is the role of dental or periodontal infection? (6) Shall we re-start the antiresorptives following healing of previous MRONJ?
Regional and temporal changes in demand for geography teachers in Poland. Results of job advert tracking in the years 2019–2020
Authors: Piróg Danuta , Hibszer Adam 
Published: December 2022

Abstract
In the literature, analysing job adverts is considered to be a credible method for collecting data about the real demand for employees with higher education. Studies on the demand for teachers based on this data source have been conducted in many countries, but never in Poland. On this basis, the research objective was to identify regional and temporal changes in the demand for geography teachers. As part of the study we tracked all job adverts addressed to geography teachers which were published online over a period of nearly two years. It turned out there were 3,438 such job vacancies in Poland, which included part-time and full-time positions. The study results indicated vast temporal and regional differences in the demand for teachers, and also a clear imbalance in the demand for geographers between Warsaw – the capital city – and the rest of the country. It should be highlighted that both the methodology and the results presented in the paper are pioneering.
Fabrication of heterojunction MnTiO3–TiO2-decorated carbon nanofibers via electrospinning as an effective multifunctional photocatalyst
Authors: Yousef Ayman , Zouli Nasser I. , Maafa Ibrahim M. , Hadidi Haitham M. , Sallam Sahar , Moosa Majed , El-Halwany M. M. 
Published: December 2022

Abstract
In this paper, we successfully synthesized heterojunction manganese titanate/titanate nanoparticles (MnTiO3–TiO2 NPs)-decorated carbon nanofibers (CNFs) employing the electrospinning process. The morphology, crystallinity, and chemical composition of the MnTiO3/TiO2-decorated CNFs is characterized via SEM, FESEM, STEM, TEM EDX, and XRD techniques. The synthesized nanocomposite exhibits good performance for photodegradation of methylene blue (MB) dye and hydrolysis of ammonia–borane complex for hydrogen releasing experiment in a batch reactor under visible light. A mathematical model was developed to predict the photocatalytic activity of the produced nanocomposite with various parameters. The operational parameters include the effect of the initial concentration, catalyst dosage, light intensity, and reaction temperature, which are studied to validate the mathematical model. The reaction rate constant of MB photodegradation is found to be 0.0153 min−1 for an initial MB concentration of 5 mg·L−1 with a catalytic dosage of 200 mg·L−1 at a reaction temperature of 25°C under a light intensity of 25 W·m−2. Similarly, the H2 generation employing TiO2@CNFs and MnTiO3/TiO2@CNFs under visible light irradiation is observed to be 0.31 mol and 2.95 mol, respectively, corresponding to an exposure of 10 min. We also demonstrated that the yield of hydrogen employing MnTiO3/TiO2@CNFs under visible light increases to 2.95 mol compared with 1.51 mol in darkness. Finally, comparisons were made between the experimental and model-predicted values of the reaction rate constant and final concentrations. Theoretical and experimental data of photocatalytic activity are found to be in good agreement for MnTiO3/TiO2@CNFs.