bluuebunny/crossref_metadata_2025_split huggingface dataset:
Insights into microbe assisted remediation in plants: a brief account on mechanisms and multi-omic strategies against heavy metal toxicity
Authors: Tariq Arneeb , Farhat Fozia 
Published: January 2025

AbstractMercury (Hg), arsenic (As), cadmium (Cd), lead (Pb) and other toxic heavy metals (HM) pose significant risks to the environment, negatively impacting the morpho-physiological and biological traits of plants. At present, toxic elements constitute a significant proportion of the food chain, exerting an impact on human health due to their mobility and biomagnification. The metal exclusion biological technique stands out for its robust performance, even when dealing with extremely low metal concentrations. Its eco-friendly nature and cost-effectiveness further enhance its value. Due to the exponential growth pattern of bacteria, these exhibit high metal persistence and are recommended for metal exclusion processes. Moreover, vacuoles like vesicles present in mycorrhizal fungi can hold extremely high levels of HM. Microbe-assisted phytoremediation primarily occurs through two mechanisms: through the direct provision of the essential nutrients and phytohormones, such as plant growth regulators, siderophores, enzymes, and mineral; or indirectly by modulating the metal detoxification process. This indirect mechanism involves microbes aiding in the accumulation and sequestration of metals in plants through the secretion of specific extracellular substances like organic acids, biosurfactants, and chelators. Moreover, the metal bioavailability and translocation in the rhizosphere are also altered via various mechanisms like acidification, precipitation, complexation or redox reactions. The understanding of the molecular and physiological processes underpinning the functions of arbuscular mycorrhizal fungi (AMF) in reducing HM toxicity, improving plant performance by procuring nutrients under HM-toxicity has significantly improved in recent years. In this review, adaptive and persistent methods related to physiological and cross-protective mechanisms in bacteria and mycorrhizal fungi (MF) resulting from the evolutionary consequences of dealing with HM toxicity have been addressed. Furthermore, the article offers details on the physiological and molecular reactions of host plants with fungi, and bacteria to HM stress, which may be useful for unveiling new knowledge about the strategies of HMs remediation.
Understanding the multifaceted role of ABA signaling in orchestrating plant developmental transition
Authors: Jiang Yupeng , Jiang Shiyu , Liu Lu 
Published: January 2025

AbstractAbscisic acid (ABA), a pivotal plant hormone once primarily associated with stress response, is now increasingly acknowledged for its indispensable role in plant development. This comprehensive review delves into the multifaceted functions of ABA in regulating various aspects of plant growth and development. From inhibiting germination to orchestrating seedling establishment, flowering time, and dormancy induction, ABA emerges as a central player in shaping plant developmental transitions. Unraveling the intricate regulatory mechanisms governing the ABA signaling pathway provides valuable insights into how plants adapt to environmental challenges while effectively managing their growth and reproductive strategies. This expanding knowledge not only highlights the significance of ABA in plant biology but also has profound implications for enhancing agricultural practices.
The Feminized Hero in Second Temple Judaism
Authors: Wills Lawrence M. 
Published: January 2025

The turbulent Second Temple period produced searching biblical texts whose protagonists, unlike heroes like Noah, Abraham, and Moses, were more everyday figures who expressed their moral uncertainties more vocally. Reflecting on a new type of Jewish moral agent, these tales depict men who are feminized, and women who are masculinized. In this volume, Lawrence M. Wills offers a deep interrogation of these stories, uncovering the psychological aspects of Jewish identity, moral life, and decisions that they explore. Often written as novellas, the stories investigate emotions, psychological interiorizing, the self, agency, and character. Recent insights from gender and postcolonial theory inform Wills' study, as he shows how one can study and compare modern and ancient gender constructs. Wills also reconstructs the social fabric of the Second Temple period and demonstrates how a focus on emotions, the self, and moral psychology, often associated with both ancient Greek and modern literature, are present in biblical texts, albeit in a subtle, unassuming manner.
Impact of order set implementation on appropriate treatment of community-acquired pneumonia (CAP)
Authors: Pham Han , Stein Michell J. , Worden Lacy J. 
Published: January 2025

Abstract

Objective:
This study aimed to evaluate appropriate antimicrobial prescribing after implementing a pneumonia order set within a community teaching hospital.

Design:
Retrospective chart review study.

Setting:
450-bed community teaching hospital.

Participants:
Patients who are 18 years of age or older admitted for treatment of community-acquired pneumonia (CAP) between October 1, 2021, and August 1, 2023.

Methods:
This retrospective cohort study aimed to evaluate a composite endpoint of appropriate empiric antimicrobial selection, dosing, and duration in accordance with the national guidelines after the implementation of a CAP order set. Secondary outcomes included comparing hospital length of stay (LOS), readmission rates, mortality rates, and Clostridium difficile infection rates.

Results:
A total of 236 patients were included (118 patients per group). Significantly more patients in the post-implementation group received guideline-concordant therapy for CAP (5.9% vs 35.6%, P < .001). Results were heavily influenced by improvements in appropriate durations of therapy (pre: 6.8% vs post: 39.9%, P < .001). There were no significant differences observed for LOS, 30-day readmission rates, C. difficile infections within 30 days, or mortality rates between groups. The order set was utilized in 66.1% of patients included in the post-implementation group.

Conclusions:
Implementing an order set significantly improved inpatient antibiotic prescribing for CAP with no difference in clinical or safety outcomes. Antibiotic order sets will be a useful tool for antimicrobial stewardship program expansion into other common community-acquired infections.
Food consumption associated with depression, anxiety and stress in students entering a public university
Authors: José Maria Eduarda Ribeiro , Ramos Ivy Evangelista Costa , Sousa Taciana Maia de , Canella Daniela Silva 
Published: January 2025

Abstract
Cross-sectional study investigated the association of fresh or minimally processed foods and ultra-processed food consumption with symptoms of depression, anxiety and stress in students from a Brazilian public university. Undergraduate students admitted in 2022 answered an online questionnaire during their first semester. Consumption of 12 subgroups of fresh or minimally processed foods and 13 of ultra-processed foods on the previous day were investigated (affirmative answer for ≥ 5 subgroups was classified as high consumption). Depression, anxiety and stress were investigated using the DASS-21 and mild to extremely severe symptoms were grouped to be compared with individuals without symptoms. Adjusted logistic regression models estimated the Odds Ratio (OR) of the association between symptoms of depression, anxiety and stress (outcomes) and food consumption (exposures), with a significance level of 5%. A total of 924 students were evaluated, of whom 57.7% presented symptoms of depression, 51.9% of anxiety and 59.4% of stress. A high consumption of fresh or minimally processed foods was observed in 80.3% of the students, with a higher frequency among those without symptoms of depression, anxiety, and stress, while 38.9% showed a high consumption of ultra-processed foods, without differences according to symptoms. High consumption of fresh or minimally processed foods was associated with a lower likelihood of symptoms of depression (OR: 0.62; p=0.011), anxiety (OR: 0.58; p=0.003) and stress (OR: 0.69; p=0.043). No association was found between ultra-processed and mental health outcomes. Actions that support and encourage the consumption of healthy food in the university environment can contribute to mental health outcomes.
They really, really, really don’t like to admit they made mistakes: A critical discourse analysis of appraisal in wrongful convictions
Authors: Ortega-Robles Carmen , Hidalgo-Tenorio Encarnación 
Published: January 2025

Abstract
Besides being unjustly incarcerated, Sabrina Butler, Kristine Bunch, Ru-el Sailor and Larry DeLisle endured various forms of police mistreatment, as detailed in a collection of transcripts from the Wrongful Conviction Podcast (WCP). Understandably enough, their criminalization had a profound impact on their perception of external and internal realities. Given their unique socio-demographic backgrounds, variations in the discursive patterns of their communicative interactions are anticipated. As extensively analyzed in sociolinguistics, both gender and ethnicity influence how individuals construct discourse; particularly, these traits appear to account for how the subjects under study express their emotions and opinions. This is because they are silenced and unable to directly confront their trauma; often, they are incapable of discussing their feelings or identifying those responsible for these traumatic events. Drawing on Appraisal Theory, this paper investigates the language of evaluation used in these texts taken from the WCP. To this end, our analysis of the data is performed using UAM CorpusTool.
Lexical influences on predictive mouse cursor movements
Authors: Kukona Anuenue 
Published: January 2025

Abstract
Two mouse cursor tracking experiments investigated lexical prediction. Participants heard predictive sentences (e.g., “What the librarian will read, which is shown here, is the…”) and viewed visual arrays with predictable targets (e.g., book) and phonological competitors (e.g., bull) or unrelated distractors (e.g., goat). Participants tasked with clicking on the (i.e., target) object referred to in sentences (Experiment 1), or with doing so interleaved with a cloze procedure (e.g., completing “What the librarian will read is this.”; Experiment 2), made predictive mouse cursor movements to targets. However, predictive attraction to phonological competitors was not observed. Implications for theories of predictive sentence processing are discussed.
Upgrading an Old Classic: The Oxford Dictionary of the Christian Church
Authors: MORRIS JEREMY 
Published: January 2025

Is the era of the reference book coming to an end? Publishers evidently don't think so. Not only have we seen an explosion in the number of handbooks, companions and dictionaries produced by the mainstream academic press in recent years, but even older, well-established ‘brands’ continue to flourish. Here is the fourth edition of Oxford University Press's ‘flagship’ Oxford dictionary of the Christian Church (ODCC), considerably expanded and revised from the third edition. Yet although libraries continue to buy works such as this, and academic colleagues to use them and refer to them, students often – if my experience is anything to go by – prefer the easier, cheaper, faster route of online sourcing, and particularly Wikipedia. A review of this edition of the ODCC has to reckon, then, not only with evaluating the content of the work itself, but, more sharply than perhaps was necessary before, with the questions of who exactly is likely to use it, and how it stands up in comparison with the competition.
The welfare-convergence dilemma: why social insurance is objectionable in the convergence conception of public justification
Authors: Li Man-kong , Wong Baldwin 
Published: January 2025

Abstract
Recently, convergence liberals, such as Kevin Vallier, argue that the principle of social insurance could be publicly justified. Our paper challenges this marriage of convergence liberalism and welfare state. We begin by examining Vallier’s three reasons for the principle of social insurance: risk aversion, injustice and the promotion of political trust. We then argue that all these reasons are intelligibly objectionable. After examining five possible responses that convergence liberals may offer, this paper concludes that the principle of social insurance is not conclusively justified in the convergence conception of public justification.
The influence of upward social comparison on social network sites on middle school students’ depression: A two-wave multiple mediation model
Authors: Yuan Mengmeng , Sun Yan , Wang Yijin , Yu Lei 
Published: January 2025

Abstract
There is a lack of longitudinal data on the relationship between upward social comparison on social network sites (SNSs) and depression and its underlying mechanisms. Therefore, this study aimed to examine the relationship between upward social comparison on social network sites and depression and analyze the mediating effects of self-concept clarity and self-esteem in this relationship. We employed a two-wave longitudinal design among 1179 Chinese middle school students. The results indicated that : upward social comparison on SNSs predicted middle school students’ depression; Self-concept clarity and self-esteem sequentially mediated the relationship between upward social comparison on SNSs and middle school students’ subsequent depression. These results suggested that three types of interventions could be effectively used to decrease the risk of depression among middle school students.
‘A little knowledge is a dangerous thing’: Rural realities, professional ideals, and the forgotten history of cottage nursing c. 1880–1939
Authors: Groppo Martha 
Published: January 2025

Abstract
This paper examines the rise and fall of cottage nursing, a controversial approach to rural healthcare that was championed across the United Kingdom from the 1880s to the interwar period. Defying the strategies being used to professionalise nursing in urban centres, cottage nursing supporters argued that nurses for the rural poor should be recruited from the lowest social classes, given only the briefest training, and prepared to do both nursing and menial domestic work. Their critics espoused the noble ideal of providing the rural poor with only the best-trained lady district nurses from the apparent moral high ground, persuasively arguing that the ‘little knowledge’ given to cottage nurses was a ‘dangerous thing’ – both for patients and for the nursing profession. And yet, cottage nursing supporters boldly challenged this position, arguing that noble ideals and excellent standards could simultaneously be pursued on behalf of rural patients and at their expense.
Microfluidic platforms for monitoring cardiomyocyte electromechanical activity
Authors: Wang Wei , Su Weiguang , Han Junlei , Song Wei , Li Xinyu , Xu Chonghai , Sun Yu , Wang Li 
Published: January 2025

AbstractCardiovascular diseases account for ~40% of global deaths annually. This situation has revealed the urgent need for the investigation and development of corresponding drugs for pathogenesis due to the complexity of research methods and detection techniques. An in vitro cardiomyocyte model is commonly used for cardiac drug screening and disease modeling since it can respond to microphysiological environmental variations through mechanoelectric feedback. Microfluidic platforms are capable of accurate fluid control and integration with analysis and detection techniques. Therefore, various microfluidic platforms (i.e., heart-on-a-chip) have been applied for the reconstruction of the physiological environment and detection of signals from cardiomyocytes. They have demonstrated advantages in mimicking the cardiovascular structure and function in vitro and in monitoring electromechanical signals. This review presents a summary of the methods and technologies used to monitor the contractility and electrophysiological signals of cardiomyocytes within microfluidic platforms. Then, applications in common cardiac drug screening and cardiovascular disease modeling are presented, followed by design strategies for enhancing physiology studies. Finally, we discuss prospects in the tissue engineering and sensing techniques of microfluidic platforms.
An ultrasensitive angular interrogation metasurface sensor based on the TE mode surface lattice resonance
Authors: Li Liye , Wu Wengang 
Published: January 2025

AbstractThe localized surface plasmon resonance metasurface is a research hotspot in the sensing field since it can enhance the light-matter interaction in the nanoscale, but the wavelength sensitivity is far from comparable with that of prism-coupled surface plasmon polariton (SPP). Herein, we propose and demonstrate an ultrasensitive angular interrogation sensor based on the transverse electric mode surface lattice resonance (SLR) mechanism in an all-metal metasurface. In theory, we derive the sensitivity function in detail and emphasize the refraction effect at the air-solution interface, which influences the SLR position and improves the sensitivity performance greatly in the wide-angle. In the measurement, a broadband light source substitutes the single-wavelength laser generally used in traditional angular sensing, and the measured SLR wavelength of broadband illuminant at normal incidence is defined as the single wavelength, avoiding the sensitivity loss from the large angle. The experimental sensitivity can reach 4304.35°/RIU, promoting an order of magnitude compared to those of SPP-sensors. This research provides a novel theory as well as the corresponding crucial approach to achieving ultrasensitive angular sensing.
Tunable MEMS-based meta-absorbers for nondispersive infrared gas sensing applications
Authors: Li Kunye , Liang Yuhao , Liu Yuxin , Lin Yu-Sheng 
Published: January 2025

AbstractIn conventional nondispersive infrared (NDIR) gas sensors, a wide-spectrum IR source or detector must be combined with a narrowband filter to eliminate the interference of nontarget gases. Therefore, the multiplexed NDIR gas sensor requires multiple pairs of narrowband filters, which is not conducive to miniaturization and integration. Although plasmonic metamaterials or multilayer thin-film structures are widely applied in spectral absorption filters, realizing high-performance, large-area, multiband, and compact filters is rather challenging. In this study, we propose and demonstrate a narrowband meta-absorber based on a planar metal–insulator–metal (MIM) cavity with a metallic ultrathin film atop. Nearly perfect absorption of different wavelengths can be obtained by controlling the thickness of the dielectric spacer. More significantly, the proposed meta-absorber exhibits angle-dependent characteristics. The absorption spectra of different gases can be matched by changing the incident angle of the light source. We also preliminarily investigate the CO2 gas sensing capability of the meta-absorber. Afterward, we propose a tunable meta-absorber integrated with a microelectromechanical system (MEMS)-based electrothermal actuator (ETA). By applying a direct current (DC) bias voltage, the inclination angle of the meta-absorber can be controlled, and the relationship between the inclination angle and the applied voltage can be deduced theoretically. The concept of a tunable MEMS-based meta-absorber offers a new way toward highly integrated, miniaturized and energy-efficient NDIR multigas sensing systems.
Aurora B inhibition induces hyper-polyploidy and loss of long-term proliferative potential in RB and p53 defective cells
Authors: Vora Shivam , Chatterjee Saptarshi , Andrew Ariel , Kumar Ramyashree Prasanna , Proctor Martina , Zeng Zhen , Bhatt Rituparna , Nazareth Deborah , Fernando Madushan , Jones Mathew J. K. , He Yaowu , Hooper John D. , McMillan Nigel A. J. , Urosevic Jelena , Saeh Jamal , Travers Jon , Cimini Daniela , Chen Jing , Gabrielli Brian 
Published: January 2025

AbstractPolyploidy is a common outcome of chemotherapies, but there is conflicting evidence as to whether polyploidy is an adverse, benign or even favourable outcome. We show Aurora B kinase inhibitors efficiently promote polyploidy in many cell types, resulting in the cell cycle exit in RB and p53 functional cells, but hyper-polyploidy in cells with loss of RB and p53 function. These hyper-polyploid cells (>8n DNA content) are viable but have lost long-term proliferative potential in vitro and fail to form tumours in vivo. Investigation of mitosis in these cells revealed high numbers of centrosomes that were capable of supporting functional mitotic spindle poles, but these failed to progress to anaphase/telophase structures even when AURKB inhibitor was removed after 2–3 days. However, when AURKB inhibitor was removed after 1 day and cells had failed a single cytokinesis to become tetraploid, they retained colony forming ability and long-term proliferative potential. Mathematical modelling of the potential for polyploid cells to produce viable daughter cells demonstrated that cells with >8n DNA and >4 functional spindle poles approach zero probability of a viable daughter, supporting our experimental observations. These findings demonstrate that tetraploidy is tolerated by tumour cells, but higher ploidy states are incompatible with long-term proliferative potential.
Diet-wide analyses for risk of colorectal cancer: prospective study of 12,251 incident cases among 542,778 women in the UK
Authors: Papier Keren , Bradbury Kathryn E. , Balkwill Angela , Barnes Isobel , Smith-Byrne Karl , Gunter Marc J. , Berndt Sonja I. , Le Marchand Loic , Wu Anna H. , Peters Ulrike , Beral Valerie , Key Timothy J. , Reeves Gillian K. 
Published: January 2025

AbstractUncertainty remains regarding the role of diet in colorectal cancer development. We examined associations of 97 dietary factors with colorectal cancer risk in 542,778 Million Women Study participants (12,251 incident cases over 16.6 years), and conducted a targeted genetic analysis in the ColoRectal Transdisciplinary Study, Colon Cancer Family Registry, and Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO). Alcohol (relative risk per 20 g/day=1.15, 95% confidence interval 1.09-1.20) and calcium (per 300 mg/day=0.83, 0.77–0.89) intakes had the strongest associations, followed by six dairy-related factors associated with calcium. We showed a positive association with red and processed meat intake and weaker inverse associations with breakfast cereal, fruit, wholegrains, carbohydrates, fibre, total sugars, folate, and vitamin C. Genetically predicted milk consumption was inversely associated with risk of colorectal, colon, and rectal cancers. We conclude that dairy products help protect against colorectal cancer, and that this is driven largely or wholly by calcium.