bluuebunny/crossref_metadata_2025_split huggingface dataset:
Joint Analysis of the Epidemic Evolution and Human Mobility During the First Wave of COVID-19 in Spain: Retrospective Study
Authors: Steinegger Benjamin , Granell Clara , Rapisardi Giacomo , Gómez Sergio , Matamalas Joan , Soriano-Paños David , Gómez-Gardeñes Jesús , Arenas Alex 
Published: May 2023

Background
The initial wave of the COVID-19 pandemic placed a tremendous strain on health care systems worldwide. To mitigate the spread of the virus, many countries implemented stringent nonpharmaceutical interventions (NPIs), which significantly altered human behavior both before and after their enactment. Despite these efforts, a precise assessment of the impact and efficacy of these NPIs, as well as the extent of human behavioral changes, remained elusive.

Objective
In this study, we conducted a retrospective analysis of the initial wave of COVID-19 in Spain to better comprehend the influence of NPIs and their interaction with human behavior. Such investigations are vital for devising future mitigation strategies to combat COVID-19 and enhance epidemic preparedness more broadly.

Methods
We used a combination of national and regional retrospective analyses of pandemic incidence alongside large-scale mobility data to assess the impact and timing of government-implemented NPIs in combating COVID-19. Additionally, we compared these findings with a model-based inference of hospitalizations and fatalities. This model-based approach enabled us to construct counterfactual scenarios that gauged the consequences of delayed initiation of epidemic response measures.

Results
Our analysis demonstrated that the pre–national lockdown epidemic response, encompassing regional measures and heightened individual awareness, significantly contributed to reducing the disease burden in Spain. The mobility data indicated that people adjusted their behavior in response to the regional epidemiological situation before the nationwide lockdown was implemented. Counterfactual scenarios suggested that without this early epidemic response, there would have been an estimated 45,400 (95% CI 37,400-58,000) fatalities and 182,600 (95% CI 150,400-233,800) hospitalizations compared to the reported figures of 27,800 fatalities and 107,600 hospitalizations, respectively.

Conclusions
Our findings underscore the significance of self-implemented prevention measures by the population and regional NPIs before the national lockdown in Spain. The study also emphasizes the necessity for prompt and precise data quantification prior to enacting enforced measures. This highlights the critical interplay between NPIs, epidemic progression, and human behavior. This interdependence presents a challenge in predicting the impact of NPIs before they are implemented.
A Web-Based Intervention to Address Risk Factors for Maternal Morbidity and Mortality (MAMA LOVE): Development and Evaluation Study
Authors: Amore Alexis Dunn , Britt Abby , Arconada Alvarez Santiago J , Greenleaf Morgan N 
Published: May 2023

AbstractBackgroundMaternal mortality in the United States is a public health crisis and national emergency. Missed or delayed recognition of preventable life-threatening symptoms and untimely treatment of preventable high-risk medical conditions have been cited as key contributors to the nation’s worsening mortality rates. Effective strategies are urgently needed to address this maternal health crisis, particularly for Black birthing populations. Morbidity and Mortality Assessment: Lifting Outcomes Via Education (MAMA LOVE) is a web-based platform that focuses on the identification of maternal morbidity and mortality risk factors.ObjectiveThe purpose of this paper is to present the conceptualization, development, heuristics, and utility evaluation of the web-based maternal mortality risk assessment and educational tool MAMA LOVE.MethodsA user-centered design approach was used to gain feedback from clinical experts and potential end users to ensure that the tool would be effective among groups most at risk for maternal morbidity and mortality. A heuristic evaluation was conducted to evaluate usability and need within the current market. Algorithms describing key clinical, mental health, and social conditions were designed using digital canvas software (Miro) and incorporated into the final wireframes of the revised prototype. The completed version of MAMA LOVE was designed in Figma and built with the SurveyJS platform.ResultsThe creation of the MAMA LOVE tool followed three distinct phases: (1) the content development and creation of an initial prototype; (2) the feedback gathering and usability assessment of the prototype; and (3) the design, development, and testing of the final tool. The tool determines the corresponding course of action using the algorithm developed by the authors. A total of 38 issues were found in the heuristic evaluation of the web tool’s initial prototype.ConclusionsMaternal morbidity and mortality is a public health crisis needing immediate effective interventions. In the current market, there are few digital resources available that focus specifically on the identification of dangerous symptoms and risk factors. MAMA LOVE is a tool that can address that need by increasing knowledge and providing resources and information that can be shared with health care professionals.
Fixation of Sacroiliac Fraktur-Luxation Using Plate 2.0 with screw 2.0 mm cortical self-tapping and 2.7 mm cortical non self-tapping
Authors: . Erwin , . Rusli , . Amiruddin , Karmil Teuku Fadrial , Asjikin Muhammad Fauzih , Kusuma Afif Yuda 
Published: May 2023

The Mixed Shih-Tzu dog, 3 years old and 4.3 kg body weight, had clinical signs of unable to stand, both rear limbs suffer from diplegic lameness so that they are only able to rely on both forelimbs. The owner said that her dog is traumatized by a four-wheeled vehicle. The results of blood profile before surgery showed physiological, only an increase in leukocyte cells 18.83 x103/µL. The radiographic examination with a ventral-dorsal position shows oblique fractures in the pelvic dexter and dislocation of the pelvic sacroiliac sinister bone. The method of handling used was open reduction internal fixation (ORIF) using a 2.0 veterinary cuttable plate (VCP) bone plate with a 2.0 mm cortical self-tapping screw for pelvic fractures and 2.7 mm cortical non-self-tapping for sacroiliac dislocations. The dog walked and showed a good progress in one week after ORIF, based on clinical and post-operative radiographic examinations, sacroiliac fracture-dislocation fixation using VCP with 2.0 mm self-tapping screw cortical for pelvic fracture and 2.7 mm non self-tapping for sacroiliac dislocation provides excellent stabilization and no visible complications.
Presence of Escherichia coli O157:H7 in Chicken Meat at Traditional Markets in Pangkalpinang City
Authors: Nurhakim Ahmad , Lukman Denny Widaya , Pisestyani Herwin 
Published: May 2023

This study was aimed to identify the presence of E. coli O157:H7 and analyze the association between factors and frequency of E. coli in chicken meat sold at Kaget Market, Pagi Market, and Pembangunan Market in Pangkalpinang City. A total of 30 chicken meat samples were collected proportionally using simple random sampling. This study was used a cross sectional method. The examination of E. coli was carried out based on SNI 2897:2008 concerning The Testing Method of Microbial Contamination in Meat, Eggs, and Milk and Their Processed Products. The E. coli O157 was confirmed with O157 latex agglutination test and H7 antiserum test. The data were analyzed using a descriptive test and risk factors were analyzed using chi-square and odds ratio. The results showed that E. coli O157:H7 was found in 2 of 3 samples (66,7%) isolated from Kaget Market. The significant risk factors (P<0,005) for the presence of E. coli were traders with age of more 45 years, kiosk distance of less than 5 meters from the highway, and washing hands using unclean water. The presence of E. coli O157:H7 will be a threat for consumer health.
Successful Combined Treatment of a Patient with Borderline Resectable Liver Metastasis of Colorectal Cancer
Authors: Stukalova O. Yu. , Polikarpov A. A. , Moiseenko A. V. , Granov D. A. 
Published: May 2023

Aim: to present the value of interventional radiology techniques in the treatment of a patient with liver metastasis of colorectal cancer.Key points. In 2013, a 60-year-old patient with stage IIIB sigmoid colon cancer, pT3N2M0 underwent resection of the sigmoid colon with the formation of hardware rectosigmoanastomosis, 6 courses of adjuvant chemotherapy were performed. In 2015, a control examination revealed metastatic liver damage. Liver resection could not be performed due to the small future residual volume, and systemic chemotherapy was not effective. The patient underwent 3 cycles of regional chemotherapy. Taking into account the pronounced positive dynamics, in the form of a decrease in tumor size and a decrease in cancer markers, the patient managed to perform an extended right-sided hemihepatectomy. No progression of the tumor process was detected during the follow-up.Conclusion. Modern possibilities of X-ray endovascular methods allow to achieve results in the treatment of patients with colorectal cancer metastases in the liver such as a decrease in metastases in size, that make liver resection possible.
J&S Publisher Problems: A Diagnostic Analytics Case Exploring Employee Expense Reimbursement
Authors: Hoelscher Jamie , Shonhiwa Trevor 
Published: May 2023

ABSTRACT
This paper aims to help students further understand employee reimbursement schemes, while simultaneously advancing the integration of data analytics in the accounting curriculum. The learning activity takes students through a comprehensive data analytics cycle to determine the root cause of employee expense reimbursement increases. The ability to leverage data analytics and possess technological agility to address business questions is an important skillset. Our paper contributes to the literature by presenting a resource that promotes the acceleration of integrating data analytics across the curriculum. The case topic is applicable to many classes, including audit (both external and internal), accounting information systems (AIS), financial, or forensic accounting, thereby promoting compliance with new accreditation standards requiring analytics throughout the curriculum. This case study helps expand the coverage of data analytics and learning experiences that emphasize the integration of information technology in the accounting curriculum.
JEL Classifications: M40; M41; M42.
Owner Exposure through Firm Disclosure
Authors: Müller Maximilian A. , Peter Caspar David , Urzúa I. Francisco 
Published: May 2023

ABSTRACTWe study whether firms avoid financial disclosures to preserve their owners' financial privacy. We find that firms named after their owner, for whom firm disclosure would more directly expose owner information, are more opaque. Eponymous owners prefer firm opacity when disclosure exposes sensitive owner information with social stigma, in rural and anticapitalist areas, and in insider-oriented settings with high secrecy and distrust. When firms are forced to disclose, eponymous owners more frequently change their firms' names, and new firms are less frequently named after their founding owners. These findings indicate that owner-level privacy concerns dampen firm-level disclosure incentives.Data Availability: The data used in this study are available from public sources listed in the paper.JEL Classifications: D82; L51; M41.
PRMT4 Facilitates White Adipose Tissue Browning and Thermogenesis by Methylating PPARγ
Authors: Zhong Yi , Wang Yilong , Li Xiaoguang , Qin Haojie , Yan Shu , Rao Caijun , Fan Di , Liu Duqiu , Deng Fei , Miao Yanli , Yang Ling , Huang Kai 
Published: May 2023

Obesity is a global health threat, and the induction of white adipose tissue (WAT) browning presents a promising therapeutic method for it. Recent publications revealed the essential role of protein arginine methyltransferase 4 (PRMT4) in lipid metabolism and adipogenesis, but its involvement in WAT browning has not been investigated. Our initial studies found that the expression of PRMT4 in adipocytes was upregulated in cold-induced WAT browning but downregulated in obesity. Besides, PRMT4 overexpression in inguinal adipose tissue accelerated WAT browning and thermogenesis to protect against high-fat diet–induced obesity and metabolic disruptions. Mechanistically, our work demonstrated that PRMT4 methylated peroxisome proliferator-activated receptor-γ (PPARγ) on Arg240 to enhance its interaction with the coactivator PR domain-containing protein 16 (PRDM16), leading to the increased expression of thermogenic genes. Taken together, our results uncover the essential role of the PRMT4/PPARγ/PRDM16 axis in the pathogenesis of WAT browning.

Article Highlights
Protein arginine methyltransferase 4 (PRMT4) expression was upregulated during cold exposure and negatively correlated with body mass of mice and humans. PRMT4 overexpression in inguinal white adipose tissue of mice improved high-fat diet–induced obesity and associated metabolic impairment due to enhanced heat production. PRMT4 methylated peroxisome proliferator-activated receptor-γ on Arg240 and facilitated the binding of the coactivator PR domain-containing protein 16 to initiate adipose tissue browning and thermogenesis. PRMT4-dependent methylation of peroxisome proliferator-activated receptor-γ on Arg240 is important in the process of inguinal white adipose tissue browning.
ANALISIS DEBIT BANJIR DAERAH ALIRAN SUNGAI (DAS) SAMPEAN BONDOWOSO JAWA TIMUR
Authors: Prasetyo Angga , Prawati Eri , Surandono Agus 
Published: May 2023

Daerah Aliran Sungai (DAS) suatu kawasan yang dibatasi oleh titik-titik tinggi di mana air yang berasal dari air hujan yang jatuh, terkumpul dalam kawasan tersebut. Air pada DAS merupakan aliran air yang mengalami siklus hidrologi secara alamiah, sirkulasi air yang tidak pernah berhenti dari atmosfer ke bumi dan kembali ke atmosfer melalui kondensasi, presipitasi, evaporasi dan transpirasi. Selama berlangsungnya daur hidrologi, yaitu siklus air dari permukaan laut ke atmosfer kemudian ke permukaan tanah dan kembali lagi ke laut. Proses terjadinya siklus hidrologi dibedakan menjadi 3 (tiga) yaitu siklus pendek, siklus sedang dan siklus panjang. Debit banjir rancangan merupakan debit banjir terbesar tahunan dengan suatu kemungkinan terjadi kala ulang tertentu, atau debit dengan suatu kemungkinan periode ulang tertentu. Dalam menghitung Analisis Debit banjir rancangan pada penelitian DAS Sampean Kabupaten Bondowoso Jawa Timur yang memiliki luas daerah sebesar 1254,48 km2 dengan panjang sungai 35,12 km dilakukan perhitungan hidrograf banjir dengan metode Hidrograf Satuan Sintetik Nakayasu.
Hasil perhitungan debit banjir rancangan menggunakan HSS Nakayasu di dapat nilai sebesar kala ulang 2 tahun adalah 7759,08 m3/detik, untuk kala ulang 5 tahun adalah 9773,87 m3/detik, untuk kala ulang 10 tahun adalah 11534,87 m3/detik, untuk kala ulang 25 tahun adalah 14273,82 m3/detik, untuk kala ulang 50 tahun adalah 16652,00 m3/detik, untuk kala ulang 100 tahun adalah 19572,58 m3/detik, untuk kala ulang 200 tahun adalah 22875,96 m3/detik, dan untuk kala ulang 1000 tahun adalah 32903,04 m3/detik.
ANALISIS TATA RUANG PARKIR RUMAH SAKIT MARDI WALUYO KOTA METRO
Authors: Gufron Fakhri M , Sriharyani Leni , Hadijah Ida 
Published: May 2023

Pada area parkir Rumah Sakit Mardi Waluyo pun, masih menggunakan tempat parkir yang seharusnya diperuntukkan untuk parkir, contohnya pada pintu masuk UGD (Unit Gawat Darurat), yang memang di peruntukkan untuk pasien yang harus mendapatkan penanganan medis yang cepat, tetapi dengan adanya parkir yang menutupi pada pintu masuk ruang UGD sangat menghambat pasien yang seharusnya membutuhkan penanganan cepat. Pola tata ruang parkir di Rumah Sakit Mardi Waluyo, masih banyak ditemukkan pola parkir / pemodelan parkir yang berbeda – beda yang masih memungkinkan bisa menjadi penyebab terjadinya penumpukkan kendaraan parkir pada Rumah Sakit Mardi Waluyo Kota Metro.
Dari analisis tata ruang parkir rumah sakit mardi waluyo kota metro untuk karakteristik ruang parkir akumulasi parkir roda dua didapat pada hari senin 241 kendaraan dan roda empat didapat pada hari selasa 108 kendaraan, durasi parkir didapat lamanya waktu parkir untuk roda empat terdapat pada hari selasa yaitu 138,42 menit dan roda dua terdapat pada hari rabu 175,41 menit, kapasitas parkir kend/jam didapat hasil terbesar untuk roda empat terdapat pada hari senin 90,93 kend/jam dan roda dua pada hari selasa 52,60 kend/jam. Ketersediaan parkir untuk roda empat terdapar pada hari selasa 1134 kend dan roda dua terdapat pada hari rabu 1438 kend. Indeks parkir didapat hasil terbesar untuk roda empat pada hari selasa 97,2% dan roda dua terdapat pada hari senin 217,1%, untuk turn over pada roda empat terdapat pada hari selasa 0,47 PTO dan roda dua terdapat pada hari senin 0,79 PTO, kebutuhan ruang parkir didapat hasil perhitungan untuk roda empat 732 SRP dan roda dua 1377 SRP, untuk pola sudut parkir Rumah Sakit Mardi Waluyo Kota Metro masih dikatakan cukup dengan menggunakan pola sudut parkir sebelumnya yaitu 45°.
KARAKTERISTIK MARSHALL CAMPURAN ASPHAL CONCRETE –BINDER COURSE (AC-BC) DENGAN BAHAN PENGISI (FILLER) ABU BATU KAPUR (LIMESTONE)
Authors: Vianda Merza Okta , Sriharyani Leni , Kurniawan Septyanto 
Published: May 2023

Jalan merupakan sarana yang sangat penting digunakan untuk transportasi bagi masyarakat. Di Indonesia , kontruksi jalan sudah banyak menggunakan campuran Laston, karna dalam campuran ini akan menghasilkan lapisan perkerasan yang kedap air dan tahan lama, harga relatif murah dibandingkan dengan kontruksi jalan beton. Dalam penelitian ini dicoba menggunakan variasi filler berupa abu batu kapur (Limestone) sebagai alternatif bahan campuran lapis aspal beton AC-BC. (Limestone) sendiri banyak dijumpai di provinsi Lampung, Khususnya di Kabupaten pesawaran yang sebagian besar digunakan untuk bahan bangunan. Jenis penelitian ini adalah penambahan variasi filler (Limestone) kedalam campuran AC-BC dengan penambahan komposisi campuran sebesar 0% (tanpa bahan tambahan), 1%, 2%, 5%, 6% dan kadar aspal 4,5%, 5%, 5,5%, 6%, 6,5%. Hasil penelitian ini menunjukan bahwa karakteristik Marshall seperti nilai VMA, VFA cenderung naik sedang nilai VIM, Flow, Stability, Marshall Quotient cenderung menurun karena pengaruh variasi filler. Di dapat KAO sebesar 5%, 5%, 5,1%, 5,5%, 5,6%, 5,8%, 5,9%, dan 6,4%. Berdasarkan spesifikasi Bina Marga 2010 di dapat penambahan variasi filler 1%, 2% dengan KAO 5,5%..
Digital Generation - Analysis of the Use of ICT by Young Poles
Authors: Stanimir Agnieszka 
Published: May 2023

Abstract
In the Europe 2020 strategy in area of smart growth one of the flagship initiatives is Digital Agenda for Europe. Implementation of this initiative will lead to wide-availability of ICT solutions to society. Young people belonging to Generation Y most often treat the computer as a natural household equipment. Regular use of the Internet is very popular among them. They increasingly use mobile solutions in the field of ICT. The intelligent use of information technology possibilities will lead to sustainable economic growth. The purpose of the study was to cheque changes in the use of ICT among young Poles, and whether related behavioural patterns are similar in other countries of the European Union. The paper concludes with main reasons differencing generations in Poland due to the using the Internet.
A Research Study on Vibrating Elements and Consuming Electricity in Predictive Maintenance
Authors: Erol Salih Seçkin 
Published: May 2023

Abstract
Mechanical looseness is one of the common failures detected on machines and mechanical systems. In this research, resonance effect that is a problem for mechanical systems has been studied within perspective of mechanical looseness failure through a bearing. A test setup has been designed, built and located in laboratory environment. A bearing in the electrical motor, that is one of the elements in the test setup construction, has been chosen for acquiring data throught acoustic, vibration and electrical consumption during the test. The purpose of this research is testing condition monitoring of mechanical looseness failure and resonance for studying comparison of different predictive maintenance perspectives. The test was implemented at the electricity frequency of 40.5 Hz that forced the electrical motor through identified rotation speed. According to the analysis results, inspecting of mechanical looseness failure and resonance problem has been detected as the most effectively by vibration analysis.
Implementing a Simulation Model for the Evaluation of BGP Updates Impact on Real-Time Applications
Authors: Hoxha Ledina 
Published: May 2023

Abstract
Border Gateway Protocol (BGP) is the actual routing inter-domain protocol in the Internet. The size, heterogenity and changebility that characterize todays Internet put always increasing requirements on BGP performance. The research community has already reported the unwanted characteristics of BGP like low integrity and slow convergence through theoretichal analyzes andd empirical measurements. Simulations allow for more realistic and flexible experiments than the theoretichal approach and also lower costs than the measurements in real life environments. The first part of this work describe theoretically characteristics and problems related to BGP nd also expectations of the today Internet users to real time applications (like VoIP). The second part concentrates in identifying and implementing of the elements for creating an integrated simulation environment for evaluating dhe effects of slowconvergence of BGP in these applications. At last it is evaluated the created environement through some small scale simmulations that try to model the now days Internet Structure.
Mandatory COVID-19 Vaccination and Free Self-Determination in the Health Field in Italy
Authors: Furramani Emanuela 
Published: May 2023

Abstract
The COVID-19 pandemic and the issues related to health emergency management have raised concerns about fundamental rights protection. One of the most complex and contentious issues in doctrine and jurisprudence is the introduction of mandatory COVID-19 vaccination for specified categories of subjects, such as healthcare workers and individuals of a specific age range, as occurred in Italy. The debate in Italy over the mandatory COVID-19 vaccination requirement focuses on whether this obligation interferes with the individual’s fundamental right to free self-determination as guaranteed by Article 32 of the Italian Constitution. In jurisprudence and doctrine, conflicting opinions are noted concerning this topic. Part of the doctrine argue that mandatory COVID-19 vaccination compromises some fundamental rights guaranteed by the Italian Constitution, such as the right to free self-determination and respect for human dignity. Other opinions find the basis of the vaccination in the community’s best interests, citing Article 32 of the Italian Constitution, which allows for the imposition of compulsory health treatment to safeguard citizens’ health. In this regard, the issue of mandatory COVID-19 vaccination requires a reflection on the balance of two fundamental rights: the individual right to free self-determination and the community’s interest in terms of protecting public health.