bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative Study of CT and MR Guided Microwave Ablation in the
Treatment of Para-vascular VX2 Liver Tumor Model in Rabbits
Authors: Ziwang Ren , Guiling Feng , Xu Feng , Zhu Liu , Bing Li , Yong Du 
Published: September 2023

Objective:
To analyze the efficacy of microwave ablation (MWA) guided by computed tomography (CT) and 1.5T magnetic resonance (MR) in the treatment of VX2 para-vascular liver tumor model in rabbits.

Materials and Methods:
Sixty para-vascular VX2 liver tumor models in rabbits were randomly divided into CT-guided microwave ablation group (CT group, n=35) and MR-guided microwave ablation group (MR group, n=35). The complete ablation rate, mean operation time, postoperative complication rate and mean survival time were compared between the two groups.

Results:
In the CT group, the rate of complete ablation was 68.6% (24/35), and the mean operation time was 42.1 ± 9.7 minutes. Three cases had ascites and one case had abdominal wall injury. In the MR group, the rate of complete ablation was 94.2% (33/35), and the mean operation time was 53.4 ± 10.9 minutes. One case was complicated with ascites. No serious complications such as pneumothorax, liver abscess, pleural effusion and diaphragm perforation were found in both groups. Between the two groups, the difference in complete ablation rate was statistically significant (P=0.006 ＜ 0.05). A statistically significant difference can also be found in mean operation time (P ＜ 0.01). The follow-up time was 21 days after the operation. As for the postoperative complication rate (11.4% in the CT group and 2.9% in the MR group, P=0.353) and mean survival time (16.9 ± 1.8 days in CT group, 18.3 ± 2.3 days in the MR group, P=0.925), the differences were not statistically significant.

Conclusion:
Compared with CT guidance, although the microwave ablation time under MR guidance was longer, the complete ablation rate under MR guidance was high, which proved that MR guidance was a more effective way of microwave ablation guidance and was worth promoting in the clinic. In this experiment, the postoperative complication rate was lower in the MR group, although the difference was not statistically significant, which may be related to the small sample size, and the subsequent study on the postoperative complication rate can increase the sample content.
Real-time Strain-encoding Cardiovascular MRI for Assessment of Regional
Heart Function in Tetralogy of Fallot Patients
Authors: Ibrahim El-Sayed H. , Agarwal Prachi P. , Ghadimi-Mahani Maryam , Stojanovska Jadranka , Sosa Antonio , Dorfman Adam L. , Lu Jimmy C. 
Published: September 2023

Background:
Tetralogy of Fallot (ToF) is the most common form of cyanotic congenital heart disease, where right ventricular (RV) function is an important
determinant of subsequent intervention.

Objective:
In this study, we evaluate the feasibility of fast strain-encoding (fastSENC; a one-heartbeat sequence) magnetic resonance imaging (MRI) for
assessing regional cardiac function in ToF.

Methods:
FastSENC was implemented to characterize regional circumferential (Ecc) and longitudinal (Ell) strains in the left ventricle (LV) and RV in postrepair
ToF. Data analysis was conducted to compare strain measurements in the RV to those in the LV, as well as to those generated by the MRI
Tissue-Tracking (MRI-TT) technique, and to assess the relationship between strain and ejection fraction (EF).

Results:
Despite normal LVEF (55±8.5%), RVEF was borderline (46±6.4%), but significantly lower than LVEF. RV strains (RV-Ell=-20.2±2.9%, RVEcc=-
15.7±6.4%) were less than LV strains (LV-Ell=-21.7±3.7%, LV-Ecc=-18.3±4.7%), and Ell was the dominant strain component. Strain
differences between fastSENC and MRI-TT were less significant in RV than in LV. There existed moderate and weak correlations for RV-Ecc and
RV-Ell, respectively, against RVEF. Compared to LV strain, RV strain showed regional heterogeneity with a trend for reduced strain from the
inferior to anterior regions. Inter-ventricular strain delay was larger for Ell (64±47ms) compared to Ecc (36±40ms), reflecting a trend for
contraction dyssynchrony.

Conclusion:
FastSENC allows for characterizing subclinical regional RV dysfunction in ToF. Due to its sensitivity for evaluating regional myocardial
contractility patterns and real-time imaging capability without the need for breath-holding, fastSENC makes it more suitable for evaluating RV
function in ToF.
Comprehensive Genomic Analysis of Puerarin in Inhibiting Bladder
Urothelial Carcinoma Cell Proliferation and Migration
Authors: Ma Yu-yang , Zhang Ge-jin , Liu Peng-fei , Liu Ying , Ding Ji-cun , Xu Hao , Hao Lin , Pan Deng , Wang Hai-luo , Wang Jing-kai , Xu Peng , Shi Zhen-Duo , Pang Kun 
Published: September 2023

Background:
Bladder urothelial carcinoma (BUC) ranks second in the incidence of
urogenital system tumors, and the treatment of BUC needs to be improved. Puerarin, a traditional
Chinese medicine (TCM), has been shown to have various effects such as anti-cancer effects, the
promotion of angiogenesis, and anti-inflammation. This study investigates the effects of puerarin
on BUC and its molecular mechanisms.

Methods:
Through GeneChip experiments, we obtained differentially expressed genes (DEGs) and analyzed these DEGs using the Ingenuity® Pathway Analysis (IPA®), Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) pathway enrichment analyses. The Cell Counting Kit 8 (CCK8) assay was used to verify the inhibitory effect of puerarin on the proliferation of BUC T24 cells. String combined with Cytoscape® was used to create the Protein-Protein Interaction (PPI) network, and the MCC algorithm in cytoHubba plugin was used to screen key genes. Gene Set Enrichment Analysis (GSEA®) was used to verify the correlation between key genes and cell proliferation.

Results:
A total of 1617 DEGs were obtained by GeneChip. Based on the DEGs, the IPA® and
pathway enrichment analysis showed they were mainly enriched in cancer cell proliferation and
migration. CCK8 experiments proved that puerarin inhibited the proliferation of BUC T24 cells,
and its IC50 at 48 hours was 218μmol/L. Through PPI and related algorithms, 7 key genes were
obtained: ITGA1, LAMA3, LAMB3, LAMA4, PAK2, DMD, and UTRN. GSEA showed that these
key genes were highly correlated with BUC cell proliferation. Survival curves showed that
ITGA1 upregulation was associated with poor prognosis of BUC patients

Conclusion:
Our findings support the potential antitumor activity of puerarin in BUC. To the
best of our knowledge, bioinformatics investigation suggests that puerarin demonstrates
anticancer mechanisms via the upregulation of ITGA1, LAMA3 and 4, LAMB3, PAK2, DMD,
and UTRN, all of which are involved in the proliferation and migration of bladder urothelial cancer
cells.
Overview of Electric Spindle Cooling Patents
Authors: Bao Yudong , Cui Guanhua , Zhou Zhentao 
Published: September 2023

Background:
The heating caused by the high-speed rotation of the motorized spindle motor and the friction-induced heating of the bearings are inevitable. After the temperature rise, the relative position and size of the spindle and other parts or components of the machine tool will differ from that before the temperature rose, forming different temperature fields and then producing different degrees of thermal expansion, leading to processing errors. This paper analyzes the characteristics and application scenarios of various cooling mechanisms for motorized spindles.

Objective:
By analyzing and discussing the patents related to the cooling methods of motorized spindles, this study aims to explore the factors of temperature variation during the working process of the motorized spindle and seeks to predict future research and development in motorized spindle cooling equipment.

Methods:
The present status of various representative patents related to the cooling device of the motorized spindle was analyzed, and the influence of the cooling device of the motorized spindle on the working effect of the spindle was obtained. According to the classification of the characteristics of the cooling device, the degree of development of the existing cooling device in the cooling effect, temperature control, and other aspects is analyzed, and the latest patent technology is expounded and compared.

Results:
This paper analyzed the characteristics of cooling devices with different structures, analyzed the main problems existing in their development, and discussed solutions to the problems existing in motorized spindle cooling mechanisms and the current and future research directions.

Conclusion:
It is found that the circulating passage cooling device has the broadest application range and cools the motorized spindle effectively. The cooling structure has little influence on the motorized spindle and prolongs its service life. The cooling effect of adaptive and systemic cooling devices is better. However, there are some defects in both of them and so there is room for further development in both the cooling efficiency and machining accuracy.
Experimental and Finite Element Investigations on the Biomechanical Consequences of Meniscectomies in the Knee Joint: A Narrative Review
Authors: Devaraj Ashwin Kumar , Acharya Kiran Kumar V. , Adhikari Raviraja 
Published: September 2023

Background:
The knowledge of the complex biomechanical behaviour of the meniscectomised knee joints is of paramount importance in various clinical situations. A combined review of experimental and finite element analysis studies examining the consequences of meniscectomies on the biomechanics of the knee joint has not been reported in the literature. Therefore, this paper presents a combined review of experimental and finite element analysis studies on the biomechanical consequences of medial and lateral meniscectomies in the knee joint.

Methods:
Experimental and FEA investigations on the association between meniscectomies and the biomechanical response of the knee joint are reviewed. The effects of partial and total meniscectomies in the medial and lateral compartments are included in this paper.

Results:
Subtotal/total medial meniscectomies cause a significant decrease in the contact area and a substantial increase in the contact stress in comparison with that in an intact knee joint. This could give rise to severe degeneration of the cartilage surface. Partial medial meniscectomy causes a modest reduction in the contact area associated with a moderate increase in contact stress. The resection of both leaflets of the meniscus results in a substantial increase in the contact pressure and a significant reduction in contact area compared with inferior leaflet resection.

Conclusion:
This review recommends partial medial meniscectomy over subtotal/ total medial meniscectomy. It also suggests performing resection of the inferior leaflet rather than resection of both the leaflets. Finally, some recommendations for future work are suggested to predict the realistic biomechanical behaviour of meniscectomised knee joints.
Developing a CDY Model for Grapes and Experimentally Validating it with an Android App that Focuses on Agro-climatic and Disease Prevention Aspects
Authors: Eswari A. , Manjunatha JG 
Published: September 2023

Introduction:
Crop development and yield are both influenced by the weather. This study has developed and analytically resolved a general agro-climatic model for grapes.

Methods:
In the field of mathematical biology, researchers, professors, and academics will find this model useful. To create the final version of the model for yield prediction, the CDY model and asymptotic analyses have been performed. Climate, disease, and grape production have been taken into consideration as dependent characteristics during the model construction process. The frequency of infection, the occurrence of disease, seasonality, and the elimination of grape output throughout each harvest cycle have been viewed as distinct qualities. Moreover, the model has been examined, and field-level data have been used to estimate the parameters collected between 2016-2021 from the nearby villages of GRS and Theni.

Results:
A description of this model’s stability analysis has also been provided. An association has been determined between the numerical validity and stability of the given analytical solution analyses. In addition, the developed Android mobile app for grapes has been validated using the proposed model under the climatic scenario.

Conclusion:
It is advised to apply the created model to estimate grape yield based on the findings obtained. A useful technique for forecasting crop yield has thus been proposed in this study.
Advances and Future Challenges in Aircraft Fuselage Section
Crashworthiness: A Critical Review
Authors: Rayhan Saiaf Bin , Chunjin Yu , Rahman Md. Mazedur , Pu Xue 
Published: September 2023

Background:
Crashworthiness studies the safety qualification of a vehicle (both airborne and road transports) to protect its occupants during an impact. Before an aircraft can receive transport certification, it must meet a number of crashworthiness requirements, such as the structure's deformation pattern, absorbed kinetic energy profile, and acceleration responses experienced by the components and human body models. Therefore, in recent times, crashworthiness has emerged as a crucial field of study during the early design stages of aircraft, along with other key parameters like weight reduction, load factor, fatigue life estimation, etc.

Objective:
The main objective of the present article is to undertake an in-depth analysis of the developments in crashworthiness related to the civil aircraft fuselage section. Furthermore, it aims to identify and address the future challenges that must be overcome to ensure the utmost safety of the occupants.

Methods:
Based on the research objectives, the available literature is categorized into three major groups: (i) finite element code validation; (ii) improvement of the crashworthiness criteria; and (iii) impact on different surface models. A methodology to solve fuselage section crashworthiness is briefly described. A review of the research articles discussing general purpose energy absorbers for crashworthy design without any implementation to the fuselage structure is out of the scope of this article.

Results:
Experimental testing of fuselage section crashworthiness is expensive and non-repeatable. Furthermore, the intricate structure of the fuselage, with its numerous components, makes it nearly impossible to devise crashworthy design solutions through classical hand calculations alone. As a result, commercial software codes play a crucial role in the development of fuselage section crashworthiness, offering valuable assistance in overcoming these limitations.

Conclusion:
Future challenges of crashworthy design involve exploring novel materials and devices to mitigate injury during controlled crash conditions. An intriguing area of study would be the analysis of lattice components, as they have the potential to enhance crashworthiness. Furthermore, as newly designed fuselage sections emerge, it will be crucial to investigate and establish the necessary requirements to ensure compliance with crashworthiness certification standards.
Analysis of the Effect of Meteorological Elements on New Energy Power
Prediction Based on Machine Learning
Authors: Shen Haibo , Deng Liyuan , Wang Lingzi , Liu Xianzhuo 
Published: September 2023

Background:
With the gradual construction of new power systems, new energy sources,
such as wind and photovoltaic power, will gradually dominate positions in the power supply structure,
directly leading the new power system to rely heavily on accurate meteorological forecasts.
High-precision and high-resolution meteorological forecasts are important technical methods to improve
the safe, stable, and economic operation of the new power system.

Objective:
Since the analysis of meteorological elements is the basis of meteorological forecasting,
in this paper, the effect of different meteorological elements including temperature, relative humidity,
air pressure, wind speed, wind direction, and radiation on the performance of power forecasting,
was analyzed by using 7 machine learning algorithms in 5 provinces in southern China.

Methods:
About 5 provinces in southern China were selected as the research objects, and 7 typical
machine learning algorithms were applied and compared, including support vector machine (SVM),
decision tree (DT), random forest (RFR), K-nearest neighbor (KNN), Linear Regression (LR),
Ridge Regression (RR), and Lasso Regression (Lasso R). At the same time, the influence of different
meteorological elements, such as temperature, relative humidity, air pressure, wind speed, wind
direction, and radiation amount, on the prediction performance of wind power and photovoltaic
power was considered. Then, the performance of different regression models was further investigated
and analyzed.

Results:
Based on the data of 10 new energy stations in 5 regions, the research on the prediction
performance of 7 machine learning methods shows that the performance of models in different regions
varies greatly. Among the 10 selected new energy stations, the RFR model and KNR model
have superior overall performance.

Conclusion:
This study shows how variable importance and prediction accuracy depend on regression
methods and climatic variables, providing effective methods to assess the interdependence of
meteorological variables and the importance of meteorological variables in predicting output power.
The Conflict between Top-down and Bottom-up Impairments in
Consciousness Disorder in Schizophrenia
Authors: Karbakhsh Hesam , Kouchakzadeh Aliakbar , Gharibzadeh Shahriar 
Published: September 2023

Introduction:
Schizophrenia, a complex psychiatric disorder, is often associated
with consciousness disorders, typically characterized by an elevated threshold of conscious
perception. Over the years, a multitude of research has been dedicated to uncovering the primary
cause of these disorders, leading to the development of several theories.

Methods:
In this article, two central answers to this problem have been reviewed. For this, the
articles that were more related to the topic were selected. Based on the relevance to the subject
of research, the main ideas of targeted articles are reordered to be comprehensible for the readers.
Finally, the judgment and conclusion of the authors about the discussed problem are presented
in this study.

Discussion:
The first theory, which we will explore in this article, suggests that the root cause
of these disorders lies in defects within bottom-up processes. These processes, fundamental to
our understanding of the world, involve the progression of sensory information from low-level
perception to high-level awareness. In individuals with schizophrenia, these processes are believed
to be compromised, leading to a distorted perception of reality. The second theory, in
contrast, attributes the cause to impairments in top-down processes. These processes, which
refer to the influence of high-level cognitive functions on lower-level sensory perception, are
also considered dysfunctional in schizophrenic patients. This dysfunction is thought to disrupt
the integration of sensory information, thereby affecting the individual's consciousness. However,
a third perspective has emerged, suggesting the coexistence of impairments in both bottom-
up and top-down processing. This perspective argues that to fully comprehend the nature
of consciousness disorders in schizophrenia, it is crucial to determine the type and severity of
both bottom-up and top-down impairments.

Conclusion:
In this review, we delve into these theories, examining the evidence supporting
each and discussing their implications for our understanding of schizophrenia. Considering
both bottom-up and top-down impairments, the third perspective offers a more holistic explanation
for these disorders. We further argue that this perspective underscores the need for a
more nuanced approach to studying schizophrenia. It suggests that future research should not
only focus on these processes in isolation but also explore their interaction and the potential
synergistic effects of their impairment. By doing so, we can hope to gain a more comprehensive
understanding of consciousness disorders in schizophrenia, which could ultimately lead to
more effective treatment strategies.
Editorial
Authors: Santacruz Aguilar Milton , Lopera Gloria Patricia , García Roldan Daniel 
Published: September 2023

Desde la invasión de las sociedades europeas al territorio americano a finales del siglo xv, los pueblos originarios han tenido que enfrentar innumerables violencias, crisis y procesos de cambio de manera ininterrumpida hasta el día de hoy. Sin embargo, la resiliencia y la lucha constante por la defensa de sus sociedades, culturas y territorios han hecho de ellos actores cada vez más relevantes en la historiografía colonial y en la historia moderna y contemporánea del continente. Esto, por supuesto, nos obliga a reconocer que cuando hablamos de “lo indígena” en América, no nos referimos a una realidad social con unas características propias que perduran de manera inmutable a lo largo del tiempo; antes bien, dicha denominación está vinculada con diferentes regímenes de alteridad que varían de acuerdo con su lugar de enunciación y su contexto histórico. Es decir, la identificación de los otros como diferentes “…es un efecto de la práctica, de ciertas interacciones específicas, y no su causa”. [1]
[1] Caballero, P. L. (2016). Introducción: los regímenes nacionales de alteridad: contextos, posicionamientos e interacciones en la constitución de la identificación como ‘indígena’. En P. L Caballero y C. Giudicelli (Eds.), Regimes Nationaux d’altérité. États-Nations et Altérités Autochtones en Amérique Latine, 1810-1950 [Regímenes nacionales de alteridad. Estados-nación y alteridades indígenas en América Latina, 1810-1950]. Presses Universitaires de Rennes.