bluuebunny/crossref_metadata_2025_split huggingface dataset:
Maternal and perinatal outcomes of sickle cell disease in pregnancy: A nationwide study in France
Authors: Corsia Alice , Joseph Laure , Beeker Nathanael , Manceau Sandra , Driessen Marine , Meunier Benoit , Cavazzana Marina , Collier Mathis , Treluyer Jean‐Marc 
Published: February 2025

SummaryThis nationwide cohort study provides a comprehensive overview of maternal and perinatal outcomes associated with sickle cell disease (SCD) during pregnancy. Using the French national health database, all singleton pregnancy‐related hospital discharges from 2013 to 2020 in women aged 15–55 (n = 5 752 080) were selected. Of these, 1022 births were to women with SCD, 308 of whom were on long‐term treatment, that is, hydroxyurea (HU) and/or transfusion programme. Pregnancies with SCD were more likely to involve pre‐eclampsia (9.6% vs. 1.7%; p < 0.001), pulmonary embolism (0.70% vs. 0.02%; p < 0.001), caesarean sections (52.8% vs. 18.2%; p < 0.001) and postpartum haemorrhage (8.3% vs. 4.1%; p < 0.001) compared to pregnancies without SCD. Preterm birth (<37 weeks) was much more common in women with SCD (28.5% vs. 5.6%). Infants born to women with SCD faced greater adverse neonatal outcomes (22.4% vs. 8.0%; p < 0.001). Although untreated SCD was linked to fewer complications than long‐term treated SCD, both conditions presented greater risks compared with pregnancies without SCD. Unexpectedly, babies born to women with SCD had a higher incidence of congenital abnormalities (6.3% vs. 3.4%; p < 0.001), not attributed to HU use. Overall, despite advances in SCD management, pregnancy in SCD remains a high‐risk condition, for both mothers and babies.
Immune‐deficient MISTRG mice support expansion of leukaemia‐initiating cells in xenograft models of paediatric acute myeloid leukaemia
Authors: Connerty Patrick , Xie Jinhan , El‐Najjar Fatima , Trahair Toby N. , Jayatilleke Nisitha , Mayoh Chelsea , Lock Richard B. 
Published: February 2025

SummaryAcute myeloid leukaemia (AML) remains a deadly disease, largely due to the persistence of drug‐resistant leukaemia‐initiating cells (LICs) which promote relapse. Therefore, effective therapies must target LICs. Patient‐derived xenografts (PDXs) are valuable for testing new therapies, though establishing AML PDX models is challenging. Two humanized mouse strains, MISTRG and NRGS, have been developed for this purpose. In this study, we show both are suitable strains for the development of AML PDXs; however, MISTRG‐derived PDXs contain 10 times higher LIC frequencies than NRGS‐derived PDXs. These differences have crucial implications for preclinical AML therapy testing and modelling relapse models of the disease.
A general dynamic learning model framework for cognitive diagnosis
Authors: Liu Zichu , Wang Shiyu , Xiao Houping , Zhang Shumei , Qiu Tao 
Published: February 2025

AbstractUnderstanding students' learning trajectories is crucial for educators to effectively monitor and enhance progress. With the rise of computer‐based testing, researchers now have access to rich datasets that provide deeper insights into student performance. This study introduces a general dynamic learning model framework that integrates response accuracy and response times to capture different test‐taking behaviors and estimate learning trajectories related to polytomous attributes over time. A Bayesian estimation method is proposed to estimate model parameters. Rigorous validation through simulation studies confirms the effectiveness of the MCMC algorithm in parameter recovery and highlights the model's utility in understanding learning trajectories and detecting different test‐taking behaviors in a learning environment. Applied to real data, the model demonstrates practical value in educational settings. Overall, this comprehensive and validated model offers educators and researchers nuanced insights into student learning progress and behavioral dynamics.
Tectono‐Sedimentary Evolution of the Distal Paleogene Andean Retroarc at 33° S: New Detrital Zircon U–Pb Geochronology From the Divisadero Largo Formation
Authors: Lothari Lucas , Suriano Julieta , Mescua José , Bertoa del Llano Macarena , Arnous Ahmad , Pingel Heiko , Strecker Manfred R. , Giambiagi Laura , Echaurren Andres , Barrionuevo Matias , Mahoney J. Brian , Cottle John M. 
Published: February 2025

ABSTRACTSedimentary basins in the distal Cenozoic Andean retroarc yield an important geological archive that provides crucial insights into the tectonic and sedimentary processes associated with the different stages of mountain building. At 33° S, the tectonic and sedimentary processes that have operated during the Neogene and Quaternary periods of Andean orogenesis are well documented, whereas information on the Paleogene period remains fragmentary and partly enigmatic. The Paleogene sedimentation in the distal retroarc at this latitude is represented by the Divisadero Largo Formation, a 70‐m‐thick sedimentary unit that has been extensively studied for its fossil content, leading to the controversial definition of the late Eocene Divisaderan South American Land Mammal Age (SALMA). New zircon U–Pb geochronological data provide a valuable age constraint for Paleogene tectonic and sedimentary processes in the Southern Central Andes. Furthermore, we present the first detailed facies analysis of the Divisadero Largo Formation, combined with a sedimentary provenance study and a seismic subsurface characterisation of this unit. Our results indicate that the age of the Divisadero Largo Formation is Palaeocene to early Eocene (~65–41 Ma). Deposition of this unit occurred in a shallow, lacustrine depositional environment with variable water depths and was characterised by a low accumulation rate of 3 m/Myr. During this time, the sediment source was predominately located in the Andean magmatic arc; however, no conclusive evidence of significant Paleogene deformation exists. These characteristics (age, depositional environment, low accumulation rate and provenance) enable a regional correlation with Paleogene deposits farther south in the Neuquén Basin. In addition, based on U–Pb geochronology and sedimentary features, a 20 Myr hiatus could be defined between the Divisadero Largo Formation and overlying synorogenic deposits, as has been proposed farther south, reflecting the northernmost record of this hiatus. Taken together, these new observations help to refine a tectono‐sedimentary model for the evolution of the Southern Central Andes retroarc basin at 33° S that comprises four stages preceding the well‐documented Miocene contraction phase: (i) Late Jurassic–Early Cretaceous extension; (ii) Late Cretaceous contraction; (iii) Palaeocene–middle Eocene tectonic quiescence; and (iv) a renewed phase of late Eocene–Oligocene extension.
Trueness of Customized Abutment Data Superimposition on Incompletely Scanned Impression: An In Vitro Study
Authors: Baek Yeon‐Wha , Kim Bongju , Kim Myung‐Joo , Kwon Ho‐Beom , Lim Young‐Jun 
Published: February 2025

ABSTRACTObjectivesThis study evaluated the feasibility and trueness of superimposing titanium customized abutment library data onto scans of abutments with incomplete areas along margins or proximal surfaces, comparing this approach to the CAD program's hole‐filling function.Material and MethodsA dental model with one implant was used. A titanium customized abutment was scanned to create abutment library data. Reference data were generated using a laboratory scanner (Medit T500) and the abutment and neighboring teeth were scanned 10 times with Medit I500, an intraoral scanner (IOS group). Superimposition with abutment library data was performed for fully scanned (F), margin‐deleted (M1 and M2), and proximal‐deleted scans (P). The “Close holes” function of exocad DentalCAD was applied to create the PF group. Trueness was assessed by comparing root mean square (RMS) and point‐based deviations against reference data using Geomagic control X. Statistical analysis was conducted using one‐way ANOVA and Tukey HSD tests.ResultsSuperimposition improved trueness compared to the IOS group, reducing RMS from 42.11 ± 1.11 to 36.37–36.61 μm in the F, M1, M2, and P groups (p < 0.001). No significant differences were observed among superimposition groups. The PF group exhibited greater deviations than all superimposition groups (p < 0.001). Point‐based analysis showed significant improvement in superimposed groups (p < 0.05), except at marginal ridges (p > 0.05). The hole‐filling function did not enhance trueness (p > 0.05).ConclusionsSuperimposing abutment library data improve the trueness of intraoral scans, even when areas along margins and proximal surfaces are incomplete.
Global Trends of Trait Matching in Avian Frugivory and Its Consequences for the Complementarity and Irreplaceability of Birds
Authors: Morán‐López T. , Campagna M. S. , Schleuning M. , García D. , Morales J. M. 
Published: February 2025

ABSTRACTIt is generally accepted that small birds cannot eat large fruits and that highly frugivorous species prefer lipid‐poor ones (morphological and nutritional trait‐matching). Yet, it is unclear if these rules operate globally and if their strength varies with latitude and on islands. This could have important functional implications for the degree of complementarity and irreplaceability of birds. We analyse avian frugivory in 59 communities across the globe and show that trait‐matching is widespread. The strength of morphological trait‐matching increased with latitude, and especially on islands, leading to high complementarity between large and small birds. However, whether this resulted in irreplaceability depended on the range of fruit sizes available in the community. Nutritional trait‐matching was also common, but did not lead to complementarity or irreplaceability because birds with contrasting diets did not show opposite responses to lipid‐poor fruits. We show that trait‐matching is pervasive, but its functional consequences are complex.
Effect of nitrogen atmosphere during 3D printing on mechanical properties of orthodontic aligners
Authors: Zinelis Spiros , Panayi Nearchos , Polychronis Georgios , Dionysopoulos Dimitrios , Papageorgiou Spyridon N. , Eliades Theodore 
Published: February 2025

AbstractThe aim of this study was to investigate the effect of low oxygen environment during printing on the mechanical properties of 3D printed aligners. Thirty‐six 3D printed rectangular (20 × 20 × 10 mm) specimens were fabricated using the SprintRay Pro 55 printer and equally divided into two groups. Eighteen of them were built under normal atmosphere conditions during printing (CON) and the rest by continuously purging pure (NIT), thereby eliminating the oxygen content. Both groups underwent post‐curing in an illuminated chamber. Three samples from each group were analyzed by attenuated total reflection Fourier‐transform infrared spectroscopy (ATR‐FTIR). The remaining specimens underwent metallographic grinding/polishing followed by nano‐indentation testing. The mechanical properties measured were: Martens Hardness (HM), indentation modulus (EIT), and elastic index (ηIT). Statistically significant differences between groups were assessed using Mann–Whitney tests (α = 0.05). Both groups showed identical ATR‐FTIR spectra and complete C = C conversion. No statistically significant differences in the parameters tested were seen. The medians (interquartile ranges) were HM CON: 68.0 N/mm2 (65.0–71.0 N/mm2), NIT: 73.0 N/mm2 (67.0–83.0 N/mm2); EIT CON: 1999.0 MPa (1952.0–2154.0 MPa); NIT: 2047.0 MPa (1702.0–2104.0 MPa); ηIT CON: 28.0% (27.2%–29.0%) and NIT: 28.9% (27.1%–31.4%). The results of this study showed that elimination of oxygen during printing does not affect the mechanical properties of 3D printed aligners.
Critical socialization in White families: Lessons learned from an antiracist parenting program
Authors: Kerr Margaret L. , Botto Inés , Byer Kay , Duncan Larissa G. 
Published: February 2025

AbstractBackgroundRacial bias develops at an early age, yet most White parents promote color‐evasive racial ideology or do not address race with children. There is a need for White parents to have developmentally appropriate race‐conscious conversations with young children to address bias and facilitate antiracist values.ObjectivesThis paper describes program development, theoretical foundations, implementation challenges, and lessons learned from the pilot of an antiracist parent training program. The program is a six‐session training for White parents of preschool‐aged children. Grounded in family science, it incorporates children's literature and guidance for parent–child communication on race and racism.Applied ExperienceThere was high interest in the program and participants responded well to the opportunity to learn from other parents. Considerable variability in parents' racial awareness impacted complexity of discussions and influenced parents' responses. Notably, child factors influenced parent outcomes, suggesting bidirectionality in racial socialization processes.Conclusion and ImplicationsParent training may be a promising avenue for addressing Whiteness and promoting antiracist action. There is a need to consider program implementation in different settings, such as with different facilitators or in less politically progressive communities. Future programs should consider how to encourage critical self‐reflection and facilitate complex discussions toward antiracist skill building.
Phytoplankton Community Stability Across Eutrophic Gradients: Insights From Annual and Monthly Timescales
Authors: Liya Wang , Zhen Yang , Limei Shi , Yang Yu , Xiaoli Shi , Min Zhang 
Published: February 2025

ABSTRACT

Exploring the response of natural community stability to anthropogenic environmental changes, such as eutrophication, is an important topic in current ecological research. Eutrophication directly affects species dynamics, abundance and succession in phytoplankton communities, potentially leading to shifts in ecological processes in these communities over multiple years. However, it remains unclear how the annual and monthly dynamics of phytoplankton communities shift along eutrophication gradients to maintain stability.

We conducted an 8‐year survey in a large shallow lake, where the entire area exhibited a gradient of eutrophication. Using this dataset, we analysed three dynamic characteristics of phytoplankton communities: biomass stability (BS), composition stability (CS) and species rank‐abundance curve change (Curve_change). These variables were analysed at annual (from 2014 to 2021, with annual data collected at each sampling site) and monthly (extending to 96 months within the same period, with monthly data) scales to examine how they changed in response to the eutrophication gradient.

Annual and monthly BS was only slightly affected by the eutrophication gradient, whereas monthly composition stability and changes in species rank‐abundance curves were significantly altered. BS correlated positively with CS but negatively with changes in the species rank‐abundance curve.

This indicates that phytoplankton can maintain BS through specific adjustments in community structure over shorter timescales, with distinct mechanisms operating across the eutrophication gradient. At high nutrient concentrations, this stability is associated with shifts in the relative abundance of non‐dominant species, which buffer fluctuations in dominant species abundances and ensure functional redundancy. In contrast, at relatively low‐nutrient concentrations, BS is achieved through compensatory dynamics among dominant species, where declines in one species are offset by increases in another with similar ecological functions. However, this internal regulatory mechanism is less evident over longer timescales.

These findings highlight the importance of timescales in studying the impact of eutrophication on phytoplankton community stability, providing important clues for assessing and predicting the response of lake ecosystems to future environmental changes.
Drought‐Induced Decreases in Abundance of Emergent Midge Subsidies Are Offset by Increased Body Size in a Prairie Stream
Authors: Siders Adam C. , Hopper Garrett W. , Whiles Matt R. , Reisinger Alexander J. , Gido Keith B. 
Published: February 2025

ABSTRACT

Emerging aquatic insects can be an important resource subsidy for a variety of terrestrial consumers, including spiders, birds, bats and lizards. Emergence flux is influenced by a variety of abiotic and biotic variables, such as temperature, drying, and predators and these variables can also control the body size of emergent insects. Despite their importance, these variables can change rapidly during drought conditions as water temperatures rise, surface area decreases and predator densities increase.

During 2018, the Konza Prairie Biological Station experienced a record drought: flow ceased in the lower reaches of Kings Creek for the first time in over 40 years of observation, leaving a series of isolated pools. We studied how the drought affected aquatic insect emergence in 12 of these pools via elevated temperatures, decreased surface area, and concentration of predators (e.g. fishes and crayfish) over a four‐week period. We returned in 2020 and sampled emergence in the same pools over 2 weeks under non‐drought conditions to compare emergence between drought and non‐drought conditions.

We found three overall patterns: (1) rates of areal emergence abundance and biomass (number or mg DM m−2 d−1) did not differ between drought and non‐drought conditions. In contrast, pool‐scale emergence abundance, but not biomass (number or mg DM pool−1 d−1), was lower during drought conditions; (2) average midge body size was larger during the drought relative to the non‐drought conditions; (3) environmental variables (e.g. temperature, pool surface area, predator biomass) were not predictive of emergence during drought and non‐drought conditions.

Fewer, but larger emergent midges (as seen under drought conditions) may represent a higher quality resource for terrestrial consumers than many smaller midges due to increased per‐capita energy yield. However, due to the overall decrease in water availability throughout the stream network, the overall emergence flux was concentrated in reaches with remaining water during the drought, making pools emergence subsidy hotspots. Overall, these contrasting responses underscore the complex nature of community responses to shifting climatic conditions.
Effects of Wildfire on Interactions Among Nematode Parasites, Mayfly Hosts and Trout Predators
Authors: Svatos Emma C. , Carvallo Fernando R. , ter Kuile‐Miller Mia K. , Gray Julia L. , Trujillo Jordan L. , Weinstein Sara B. , Fairchild Matthew P. , Kanno Yoichiro , Preston Daniel L. 
Published: February 2025

ABSTRACT

Wildfire activity is increasing globally, highlighting the need to understand how fire disturbance affects species interactions. In particular, few studies have examined how fire influences interactions among parasites, hosts and predators in freshwater streams.

We characterised host–parasite and parasite–predator interactions involving nematode parasites (Family Mermithidae), mayfly hosts (Order Ephemeroptera) and trout predators (Salvelinus fontinalis, Salmo trutta and Oncorhynchus clarkii) at 8 burned and 8 unburned stream sites in the southern Rocky Mountains for 2 years following severe wildfires.

Mayfly density, infection probability, and density of infected mayflies (infected mayflies/m2) were all lower at burned sites 1 year after fire but returned to levels similar to unburned sites after 2 years. Density of infected mayflies increased with overall mayfly density; however, infection prevalence (%) ranged from 0% to 26% across burned and unburned streams, and there was no relationship between mayfly density and infection prevalence.

Based on dissections of > 20,000 mayflies, intermediate‐size (4–6 mm) mayflies in the family Baetidae had the highest infection probability and were also the most common mayfly family and size class found in trout stomachs. Wildfire did not affect the number of mermithids consumed per trout, and infection prevalences of mayflies consumed by trout were significantly lower than in the benthos, suggesting predator‐avoidance behaviour by infected mayflies.

Overall, our results suggest that mermithid nematode responses to fire reflected changes in host density, consistent with the single‐host life cycle of mermithids. These results help integrate host–parasite–predator interactions into our understanding of disturbance ecology in freshwater streams, with implications for parasite roles in energy flow through food webs.
Sound Art Geographies: Listening at the Limits of Audibility
Authors: Burdon George 
Published: February 2025

ABSTRACTThis paper explores the generative yet underexamined relation between human geography and sound art. Sound art has long been concerned with issues of spatiality, place and environment and yet interest in sound art from human geographers has been somewhat sparse, particularly when compared to the wealth of literature on visual art in the discipline. In this context, the paper does three things. First, it reviews debates in sound art theory to highlight how sound art is often discussed as performing critical interventions in perceptions of space. Second, it examines how such interventions have been engaged by human geographers in the limited body of literature currently existing on sound art in the discipline, which suggests that sound art can reveal some of the unheard histories, experiences and voices of spaces. Finally, it suggests that geographic engagements with sound art might productively explore the contention, legible in recent work in sound studies and philosophy, that sound art can create spaces of affect in which an audience is exposed to the limits of prevailing schemas of audibility. Rather than producing a better or more accurate representation of space, the paper argues that sound art instead can provoke affective encounters with alternative temporalities, silences and non‐human life.
Gendered Inequalities: A Comparative Analysis of Gendered Experiences of Inequality in Technology in Egypt and the United Kingdom
Authors: Maatwk Fatima 
Published: February 2025

ABSTRACTInequality experiences are strongly gendered and context‐specific. Drawing on semi‐structured in‐depth interviews with technology industry employees in Egypt and the United Kingdom, this article explores intersectionality and the contextuality of gendered inequalities. It investigates how context shapes gendered experiences of inequality and how this plays out at the workplace. The paper offers a cross‐cultural comparison which shows that the experiences of women in tech reflect the cultural construction of gender roles and the sectoral dynamics. By contrasting the Middle Eastern context of Egypt and the Western context of the United Kingdom, the article unpacks the complicated influence of cultural contexts on the experiences of women in tech and shows that inequality is individually unique, complex, and contextual. The study reveals the mechanisms by which contextual gender dynamics shape the workplace experiences of inequality, and the relational and complex nature of intersectionality.