bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reperfusion measurements, treatment time, and outcomes in patients receiving endovascular treatment within 24 hours of last known well
Authors: Hong Lan , Ling Yifeng , Zhang Yiran , Yang Lumeng , Li Siyuan , Liu Xinyu , Dong Qiang , Cheng Xin 
Published: January 2023

AbstractAimsThe aim of this study was to explore the interaction between reperfusion and treatment time on the outcomes of patients undergoing endovascular treatment presenting within 24 h of last known well, and to compare the predictive ability of different reperfusion measurements on outcomes.MethodsEligible patients from a single‐center cohort were enrolled in this study. Reperfusion was assessed using reperfusion index (decreased volume of hypoperfusion lesion compared with baseline) measured by repeated perfusion imaging, and modified treatment in cerebral ischemia score measured by digital subtraction angiography, respectively. The interactions between reperfusion measurements and treatment time on outcomes were explored using multivariate‐adjusted logistic and linear regression models. The predictive abilities of reperfusion measurements on outcomes were compared using area under the receiver operating characteristic curve (ROC‐AUC) and values of R‐square.ResultsReperfusion index and treatment time had significant interactions on 3‐month modified Rankin Scale (mRS) 0–2 and infarct growth (p for interaction <0.05). Although the AUCs were statistically similar (AUCs of mRS 0–2 prediction, mTICI≥2b:0.63, mTICI≥2c:0.59, reperfusion index≥0.5:0.66, reperfusion index ≥0.9:0.73, P value of any of the two AUCs >0.05), reperfusion index≥0.9 showed the highest R‐square values in outcome prediction (R‐square values of 3‐month mRS 0–2 and infarct growth = 0.21) among all the reperfusion measurements.ConclusionTreatment time mitigated the effect of reperfusion on outcomes of patients receiving endovascular treatment within 24 h of last known well. Reperfusion index≥0.9 might serve as a better proxy of good outcomes compared with other reperfusion measurements.
Effect of sucrose levels on dynamic rheology properties of dough during fermentation process
Authors: Dongdong Xie , Yanan Lei , Xing Li 
Published: January 2023

SummaryThe effect of sucrose levels on the rheo‐fermentation properties of dough were studied. Compared with control group, dough forming time and dough strength were enhanced in the sucrose dough, and the water absorption and development time were significantly reduced. Dough with 10% sucrose had the highest resistance, and 4% and 10% sucrose increased the toughness of the dough. 2% sucrose dough had the better leavening ability. There was lower strong bound water dough and higher weakly bound water in 2% sucrose dough compared with the other sucrose dough. With increasing sucrose levels, the content of free water in dough increased significantly. There was no growth of yeast in the sugar‐free medium (0%), 2% sucrose was much more suitable for yeast growth, while 6% and 10% sucrose levels inhibited yeast growth. Compared with 2% sucrose group, yeast produced more glycerol content and ethanol content in 6% and 10% sucrose medium. In conclusion, 2% sucrose dough had a better and smoother development fermentability, and a better yeast growth, sucrose levels affected the rheological properties of dough by affecting the migration and distribution of water, growth and metabolites of yeast.
Defining ferritin clinical decision limits to improve diagnosis and treatment of iron deficiency: A modified Delphi study
Authors: Naveed Kanza , Goldberg Nicola , Shore Eliane , Dhoot Arti , Gabrielson Denise , Goodarzi Zahra , Lin Yulia , Pai Menaka , Pardy Natasha A. , Robinson Sue , Andreou Roseann , Sood Manish , Price Vicky , Storm Sherri , Verduyn Ashley , Parker Michelle L. , Fralick Michael , Beriault Daniel , Sholzberg Michelle 
Published: January 2023

AbstractBackgroundIron deficiency is highly prevalent worldwide and is an issue of health inequity. Despite its high prevalence, uncertainty on the clinical applicability and evidence‐base of iron‐related lab test cut‐offs remains. In particular, current ferritin decision limits for the diagnosis of iron deficiency may not be clinically appropriate nor scientifically grounded.MethodsA modified Delphi study was conducted with various clinical experts who manage iron deficiency across Canada. Statements about ferritin decision limits were generated by a steering committee, then distributed to the expert panel to vote on agreement with the aim of achieving consensus and acquiring feedback on the presented statements. Consensus was reached after two rounds, which was defined as 70% of experts rating their agreement for a statement as 5 or higher on a Likert scale from 1 to 7.ResultsTwenty‐six clinical experts across 10 different specialties took part in the study. Consensus was achieved on 28 ferritin decision limit statements in various populations (including patients with multiple comorbid conditions, pediatric patients, and pregnant patients). For example, there was consensus that a ferritin <30 μg/L rules in iron deficiency in all adult patients (age ≥ 18 years) and warrants iron replacement therapy.ConclusionConsensus statements generated through this study corresponded with current evidence‐based literature and guidelines. These statements provide clarity to facilitate clinical decisions around the appropriate detection and management of iron deficiency.
How Does the Design Guidelines for Traditional Cultural Artefacts Inspire Design in a Culturally Inspired Design Process? A Comparative Study with Novice Design Students
Authors: Dong Yenan , Zhu Shangshang , Li Wenjie , Lin Minxi 
Published: January 2023

AbstractDesign guidelines for traditional cultural artefacts play an important role in Culturally Inspired Design (CID) activities and design education. In this paper, a comparative study was performed to assess the impact of present‐day design guidelines for traditional Chinese cultural artefacts on novice designers in a CID process. In all, 42 novice designers enrolled in a cultural product design course participated in this study, under two different design conditions: an unaided condition and a guideline‐aided condition. Each condition includes three stages: identification stage, translation stage and implementation stage. In the unaided condition, each participant was asked to finish an investigative report on traditional cultural artefacts without any guidance and then carry out a detailed cultural product design. These results were then compared with those of the participants in the guideline‐aided condition, who received a design guideline for traditional cultural artefacts. The results were assessed by expert raters against six design metrics: breadth, depth, quantity, variety, novelty and quality. They revealed that the design guideline for traditional cultural artefacts in a CID process promoted the analysis of cultural features and increased the novelty and quality of design outcomes but resulted in decreased variety. We propose that the design guideline for traditional cultural artefacts may be useful as part of the design process and as a pedagogical tool in cultural creative design, but the best moment at which to introduce the design guideline should be further examined.
Possible range extension in the endangered and understudied winghead shark (Eusphyra blochii)
Authors: Lubitz Nicolas , Barnett Adam 
Published: January 2023

AbstractHere the authors report on a possible range extension in the rare and understudied winghead shark (Eusphyra blochii). A specimen was captured by recreational fishermen in Moreton Bay, Queensland, Australia, c. 800 km south of its current distribution. As winghead sharks show a clumped distribution in Australia associated with river outflow, Moreton Bay, with its large catchment area, may represent a suitable habitat for the species and previous occurrence may have gone undetected. Alternatively, climate change may have caused a recent southward shift in winghead sharks, as observed in other elasmobranch species along Australia's East Coast.
Evidence of potential establishment of pink salmon Oncorhynchus gorbuscha in Scotland
Authors: Skóra Michał E. , Jones John Iwan , Youngson Alan F. , Robertson Sean , Wells Alan , Lauridsen Rasmus B. , Copp Gordon H. 
Published: January 2023

AbstractIn spring 2022, pink salmon Oncorhynchus gorbuscha smolts were recorded in the UK. Fish were caught in the Rivers Thurso and Oykel in Scotland between 13 and 17 March. To the authors’ knowledge, this is the first observation of O. gorbuscha smolts in Europe outside the Scandinavian and Kola peninsulas, including other tributaries of the White and Barents Seas. It also provides evidence of successful spawning in 2021 and completion of the freshwater phase of the life cycle, and indicates the possibility for potential establishment of an O. gorbuscha population in Great Britain.
Occurrence and seasonality of Gyrodactylus salaris and G. salmonis (Monogenea) on Arctic char (Salvelinus alpinus (L.)) in the Fustvatnet lake, Northern Norway
Authors: Mo Tor Atle , Hansen Haakon , Hytterød Sigurd 
Published: January 2023

AbstractGyrodactylus spp. (Monogenea) were found on 16.9% (233 out of 1376) Arctic char, Salvelinus alpinus (L.), sampled from September 2010 to October 2011 in the Fustvatnet lake, Northern Norway. Two species were identified: G. salaris Malmberg, 1957, and G. salmonis Yin & Sproston, 1948. Gyrodactylus salaris was only found on Arctic char larger than 28 cm and only in samples obtained in the autumn (September and October). Gyrodactylus salmonis was found on Arctic char of all sizes (11–47 cm) and throughout the year, with a small peak in abundance in the late autumn (November). Gyrodactylus salaris was found to prefer the tail and dorsal fin. Based on the results, we recommend that surveys of Arctic char for the presence of G. salaris are based on the examination of the fins of large fish sampled during the spawning season (autumn).
Preparation and characterization of forward osmosis cellulose acetate butyrate/OH‐functionalized multiwalled carbon nanotube membrane for the concentration of bitter orange juice
Authors: Bidaki Ali , Mousavi Seyed Mahmoud , Kiani Shirin , Hosseini Fatemeh 
Published: January 2023

AbstractAs an essential process in food industry, fruit dewatering should have the least impact on the nutritional values of the product. In this research, bitter orange juice was concentrated via the forward osmosis (FO) process for the first time. For this purpose, cellulose acetate butyrate (CAB)/OH‐functionalized multiwalled carbon nanotubes (FMWCNTs) membranes were prepared using various nanofiller concentrations. The obtained membranes were characterized in terms of their morphology, porosity, water contact angle, chemical structure, tensile properties, and pure water flux. During the FO process, NaCl solution was applied as the draw solution (DS), and the concentration of NaCl was varied (1.2, 2.2, and 4.2 M) to assess its effect on the process performance. Increasing FMWCNTs loading in the casting solution up to 0.3 wt% boosted the membrane porosity, hydrophilicity, elastic modulus, and pure water flux. The CAB membrane incorporated with 0.3 wt% nanofiller and the DS with 4.2 M NaCl concentration represented the highest water flux (29.93 L/m2h) in the FO experiment and provided the maximum turbidity (1545 NTU) and viscosity (4.64 cP) of the treated feed. According to the obtained results, the developed CAB/FMWCNTs membrane proved promising in the FO concentration of fruit juice.Practical ApplicationsBitter orange juice was concentrated via the FO process using the developed CAB/OH‐FMWCNTs membranes. According to the results, water flux, and thus the dewatering efficiency increased and reached its highest value using the CAB membrane incorporated with 0.3% FMWCNTs. Since membrane processes operate at low temperatures and do not deteriorate the concentrate quality, FO concentration of bitter orange juice using the membrane modified in this study can be a superior alternative to the conventional thermal methods.
The longitudinal development of students' well‐being in adolescence: The role of perceived teacher autonomy support
Authors: Kleinkorres Ruben , Stang‐Rabrig Justine , McElvany Nele 
Published: January 2023

AbstractAlthough a decline in adolescents' well‐being has repeatedly been reported, longitudinal evidence for this development is rare and time‐varying factors like teacher autonomy support that could be associated with this trend have sparsely been investigated. Therefore, the present study examined how the temporal development of perceived autonomy support from their German language arts teachers is related to changes in four different facets of students' well‐being. Longitudinal data from 3446 adolescents from Germany (NSchools = 178) on five measurement points (Grades 5–9) were analyzed using latent growth curve models. Satisfaction with school, enjoyment of school, and self‐rated health decreased over time, while social integration remained stable. Perceived teacher autonomy support also declined between Grades 5 and 9. Furthermore, baseline levels of perceived teacher autonomy support and facets of well‐being were positively related. Finally and most importantly, our results indicated that changes in perceived teacher autonomy support were positively associated with the development of satisfaction with school, enjoyment of school, and self‐rated health, but not social integration. The findings suggest that perceived teacher autonomy support plays an important role in the development of students' well‐being in adolescence.
The Effect of Gut Microbiota on the Progression of Intervertebral Disc Degeneration
Authors: Yao Bo , Cai Youquan , Wang Weiguo , Deng Jia , Zhao Lei , Han Ziwei , Wan Li 
Published: January 2023

ObjectiveIntervertebral disc degeneration (IDD) is the main cause of back pain, and its treatment is a serious socio‐economic burden. The safety and treatment of fecal microbiota transplantation (FMT) has been established. However, the relationship between FMT and IDD still unclear. We aimed to explore whether FMT plays a role in IDD to provide a reference for the treatment of IDD.MethodsAn experimental model of IDD was established using 2‐month‐old male Sprague–Dawley rats. FMT was performed by intragastric gavage of IDD rats with a fecal bacterial solution. Rat serum, feces, and vertebral disc tissue were collected after surgery for 2 months. The levels of TNF‐α, IL‐1β, IL‐6, matrix metalloproteinase (MMP)‐3, MMP‐13, Collagen II, and aggrecan in the serum or vertebral disc tissue were measured by an enzyme‐linked immunosorbent assay, immunohistochemistry, quantitative real‐time polymerase chain reaction, or western blotting. We also examined the pathology of the vertebral disc tissue using hematoxylin and eosin (HE) and safranin O‐fast green staining. Finally, we examined the gut microbiota in rat feces using 16 S rRNA gene sequencing.ResultsWe found that the expression of TNF‐α, IL‐1β, IL‐6, MMP‐3, MMP‐13, NLRP3 and Caspase‐1 increased in the IDD group rats. In contrast, Collagen II and aggrecan levels were downregulated. Additionally, vertebral disc tissue was severely damaged in the IDD group, with disordered cell arrangement and uneven safranin coloration. FMT reversed the effects of IDD modeling on these factors and alleviated cartilage tissue damage. In addition, FMT increased the gut microbiota diversity and microbial abundance in rats treated with IDD.ConclusionOur findings suggest that FMT has a positive effect in maintaining cellular stability in the vertebral disc and alleviating histopathological damage. It affects the diversity and abundance of gut microbiota in rats with IDD. Therefore, FMT may serve as a promising target for amelioration of IDD.
Incidence and Risk Factors for Postoperative Ileus after Posterior Surgery in Adolescent Idiopathic Scoliosis
Authors: Zhang Zhuang , Hu Bo‐wen , Li Jing‐chi , Yang Hui‐liang , Liu Li‐min , Song Yue‐ming , Yang Xi 
Published: January 2023

ObjectivePostoperative ileus (POI) is a relatively common complication after spinal fusion surgery, which can lead to delayed recovery, prolonged length of stay and increased medical costs. However, little is known about the incidence and risk factors of POI after corrective surgery for patients with adolescent idiopathic scoliosis (AIS). This study was performed to report the incidence of POI and identify the independent risk factors for POI after postoperative corrective surgery.MethodsIn this retrospective cohort study, A total of 318 patients with AIS who underwent corrective surgery from April 2015 to February 2021 were enrolled and divided into two groups: those with POI and those without POI. The Student's t test, Mann–Whitney U test, and Pearson's chi‐square test were used to compare the two groups regarding patient demographics and preoperative characteristics (age, sex and the major curve type), intraoperative and postoperative parameters (lowest instrumented vertebra [LIV], number of screws, and length of stay), radiographic parameters (T5–12 thoracic kyphosis [TK], T10–L2 thoracolumbar kyphosis and height [TLK and T10–L2 height], L1–S1 lumbar lordosis [LL], and L1–5 height). Then, a multivariate logistic regression analysis was used to identify independent risk factors for POI, and a receiver operating characteristic (ROC) curve was performed to assess the predictive values of these risk factors.ResultsForty‐two (13.2%) of 318 patients who developed POI following corrective surgery were identified. The group with POI had a significantly longer length of stay, more lumbar screws, higher proportions of a major lumbar curve and lumbar anterior screw breech, and a lower LIV. Among radiographic parameters, the mean lumbar Cobb angle at baseline, the changes in the lumbar Cobb angle, and T10–L2 and L1–5 height from before to after surgery were significantly larger in the group with POI than in the group without POI. Multivariate logistic regression analysis showed that large changes in T10–L2 (odds ratio [OR] =2.846, P = 0.007) and L1–5 height (OR = 31.294, p = 0.000) and lumbar anterior screw breech (OR = 5.561, P = 0.006) were independent risk factors for POI. The cutoff values for the changes in T10–L2 and L1–5 height were 1.885 cm and 1.195 cm, respectively.ConclusionIn this study, we identified that large changes in T10–L2 and L1–5 height and lumbar anterior screw breech were independent risk factors for POI after corrective surgery. Improving the accuracy of pedicle screw placement might reduce the incidence of POI, and greater attention should be given to patients who are likely to have large changes in T10–L2 and L1–5 height after corrective surgery.
Do these jeans make me feel fat? Exploring subjective fatness, its workplace outcomes, and rethinking the role of subjectivity in the stigmatization process
Authors: Johnson Michael A. , Schminke Marshall , De Cremer David 
Published: January 2023

AbstractPersonal, work, and societal concerns about obesity and body fatness have triggered research on it across multiple domains. However, the organizational literature has been hampered by a significant shortcoming in considering it solely as an objective construct, despite research in other disciplines demonstrating a critical subjective component to how body fatness is experienced. To address this conceptual and theoretical challenge, we draw on stigma theory to explore the workplace implications of subjective fatness, or how big one feels in their own mind. We utilize and extend stigma theory by integrating it with medical research. In doing so, we shed new light on the subjective nature of the self‐devaluation process that occurs in stigmatized individuals. We argue that this self‐devaluation process is the mechanism by which subjective body fatness influences work performance. We test these hypotheses across three studies that constructively replicate results across multiple design types (multi‐rater, time‐lagged, & bivariate latent‐change model) and diverse geographic samples. Results consistently show that subjective fatness exerts a stronger impact on performance than objective fatness, and this influence is mediated by self‐devaluation. In all, our work indicates it is not how big one is but how big one feels that most affects work performance.
Infant sex at birth and long‐term maternal mortality
Authors: Grandi Sonia M. , Hinkle Stefanie N. , Mumford Sunni L. , Sjaarda Lindsey A. , Grantz Katherine L. , Mendola Pauline , Mills James L. , Pollack Anna Z. , Yeung Edwina , Zhang Cuilin , Schisterman Enrique F. 
Published: January 2023

AbstractBackgroundMaternal adaptations may vary by foetal sex. Whether male infants influence long‐term mortality in mothers remains uncertain.ObjectiveThe objective of the study was to examine whether male infants increase the risk of maternal mortality.MethodsThis study included pregnant women enrolled at 12 US sites from 1959 to 1966 in the Collaborative Perinatal Project (CPP). Collaborative Perinatal Project records were linked to the National Death Index and the Social Security Master Death File to ascertain deaths until 2016. Foetal sex was determined by infant sex at birth, defined as the total number of male or female infants in pregnancies prior to or during enrolment in the CPP. In secondary analyses, exposure was defined as infant sex at the last CPP delivery. Outcomes included all‐cause and underlying causes of mortality. We used Cox proportional hazards models weighted by the number of prior live births and stratified our models by parity and race/ethnicity.ResultsAmong 48,188 women, 50.8% had a male infant at their last registered CPP pregnancy and 39.0% had a recorded death after a mean follow‐up of 47.8 years (SD 10.5 years). No linear association was found between the number of liveborn males and all‐cause mortality (primipara women: HR 1.02, 95% CI 0.95, 1.09, multipara women, 1 prior live birth: HR 0.96, 95% CI 0.89, 1.03, multipara women, ≥2 prior live births: HR 0.97, 95% CI 0.85, 1.11). A similar trend was noted for cardiovascular‐ and cancer‐related mortality. At the last delivery, women with a male infant did not have an increased risk of all‐cause or cause‐specific mortality compared to women with a female infant. These findings were consistent across racial/ethnic groups.ConclusionsWomen who give birth to male infants, regardless of number, are not at increased risk of all‐cause and cause‐specific mortality. These findings suggest that giving birth to male infants may not independently influence the long‐term health of women.