bluuebunny/crossref_metadata_2025_split huggingface dataset:
Complications Following Surgical Management of Zenker Diverticulum: A Comparative Analysis of Endoscopic and Open Approaches
Authors: DeKloe Jefferson , Shing Samuel R. , Herzig Lia , Bertoni Dylan , Tibbetts Kathleen M. 
Published: January 2025

AbstractObjectiveWe aim to explore the differences in complication rates in endoscopic versus open transcervical treatment of Zenker diverticulum.Study DesignRetrospective Cohort Study from January 1, 2015 to December 31, 2023.SettingQueries of the TriNetX database's United States Collaborative Network.MethodsA retrospective cohort study was conducted using patients ≥18 years old diagnosed with Zenker diverticulum selected from the TriNetX United States Collaborative Network. Patients undergoing open and endoscopic diverticulectomy between 2015 and 2023 were identified and divided into cohorts and propensity score matched by age, sex, race, ethnicity, and common comorbidities.ResultsPatients that underwent transcervical approach (n = 1033), when compared to patients that underwent endoscopic approach (n = 2182), had higher rates of dysphonia (odds ratio [OR]: 2.44; 95% confidence interval [CI]: 1.47‐4.05; P = .001), long‐term enteral feeding access (OR: 3.08; 1.74‐5.46; P > .001), and infection (OR: 6.65; 3.50‐12.65; P > .001). No significant difference was found in rates of esophageal perforation (OR: 1.60; 0.93‐2.75; P = .087) or persistent postoperative dysphagia (OR: 1.03; 0.86‐1.23, P = .75). There was no significant difference in the number of patients receiving repeat diverticulectomy procedures (OR: 0.83; 0.58‐1.19; P = .314).ConclusionBased on analysis of a large healthcare database, endoscopic Zenker diverticulectomy is associated with rates of postoperative dysphonia, enteral feeding, and soft tissue infection. Both the open and endoscopic approaches offer relative advantages not captured by this population‐level analysis. Thus, judicious selection of patients based on comorbidities and anatomical factors is essential for optimizing outcomes.
Perioperative Caregiver Education Using Animated Videos for Pediatric Tonsillectomy: A Randomized Controlled Study
Authors: Roy Catherine F. , Turkdogan Sena , Nguyen Lily H.P. , McHugh Tobial , Daniel Sam J. , Yeung Jeffrey C. 
Published: January 2025

AbstractObjectiveInformation technologies may enhance our traditional perioperative teaching by providing more comprehensive information beyond the clinical visit. This quality improvement study aims to assess whether the implementation of an animated surgical video improves caregiver satisfaction for children undergoing adenotonsillectomy.Study DesignProspective, single‐blinded randomized‐controlled trial was conducted between March 1 and October 1, 2023.SettingTertiary care academic pediatric hospital.MethodsA consecutive series of patients and their primary caregivers were randomly allocated to either the control arm, in which they received traditional patient education, or the intervention arm, additionally gaining access to the multimedia platform summarizing the surgical pathway for an adenotonsillectomy. Outcomes included caregiver satisfaction using the Care Transitions Measures (CTM‐15) questionnaire, resource utilization, and qualitative feedback analysis.ResultsA total of 100 patients (50 in each arm) completed the postintervention questionnaires (mean age 5.2 ± 3.0 years, female:male: 9:10) after undergoing an adenoidectomy (N = 28), tonsillectomy (N = 3), or both (N = 69). CTM‐15 scores were high in both groups, with no observed difference between the intervention and control groups 85.82 12.91 versus 85.41 16.21, respectively, P = .89). Unplanned postoperative visits were comparable between groups, however, caregivers in the intervention arm were less likely to call a medical professional on more than 1 occasion postoperatively (16% vs 2%, P = .042). Most caregivers within the intervention arm agreed that the animated platform was interesting (94%) and useful (98%).ConclusionAnimated surgical guides are an alluring complementary modality to standard clinician‐led teaching and may help reduce perioperative resource utilization.
Investigation of Third Window Symptoms in Patients With Enlarged Vestibular Aqueduct: A Pilot Study
Authors: Noij Kimberley S. , Huang Emily Y. , Samaha Nadia L. , Walsh Jonathan M. , Ward Bryan K. , Carey John P. , Jenks Carolyn M. 
Published: January 2025

AbstractObjectiveTo assess if patients with enlarged vestibular aqueduct (EVA) experience symptoms characteristic of other third mobile window disorders such as superior semicircular canal dehiscence syndrome (SCDS).Study designCross‐sectional study.SettingTertiary care center.MethodsAdult and pediatric patients with EVA were screened. Patients with additional middle or inner ear pathology were excluded. The included patients and parents of pediatric patients were asked to complete a survey regarding symptoms, including autophony, hyperacusis, and sound‐ and pressure induced dizziness.ResultsOf the 121 patients who met inclusion criteria, 36 patients and parents completed the questionnaire (15 children and 21 adults). Adult EVA patients appeared to suffer from similar rates of hyperacusis (67%), autophony (52%), pressure induced dizziness (38%), ear fullness (62%), and spontaneous dizziness or vertigo (67%) compared to reported rates among SCDS patients. Children with EVA also appeared to have similar rates of hyperacusis (67%), ear fullness (47%), and spontaneous dizziness or vertigo (40%), while pressure induced dizziness (13%) and autophony (20%) seem less common in children and sound induced dizziness appears less common in both children and adults (13% and 14% respectively).ConclusionThis is the first study investigating the prevalence of typical third‐window symptoms in patients with EVA. We found an overlap in the prevalence of several specific and nonspecific third window symptoms for patients with EVA and SCDS.
Methodological description of knowledge translation: Implementation of clinical practice guidelines into clinical practice
Authors: Campione Elizabeth , Wampler Meredith , Newell Alaina 
Published: January 2025

AbstractThis methodological paper explores the intricacies of implementing evidence‐based medicine in the health care sector specifically focusing on the clinical practice guideline (CPG) published by the American Physical Therapy Association's Academy of Oncologic Physical Therapy for diagnosing upper quadrant lymphedema secondary to cancer (diagnosis CPG). Although CPGs are widely available, their implementation into clinical practice remains inconsistent, slow, and complex. To address this challenge, this paper employs the Knowledge‐to‐Action framework, offering a detailed description of the seven stages through the lens of an in‐progress case study on the implementation of the diagnosis CPG. This paper underscores the important role of knowledge translation in identifying both barriers and facilitators to effective CPG implementation. Through targeted strategies, such as stakeholder engagement and adaptation of interventions, this paper offers a framework for aligning clinical practice with evidence‐based recommendations to improve overall workflow and improved patient outcomes.
Visible GeV ALP from TeV Vector‐Like Leptons
Authors: de Giorgi Arturo , Zamoro Marta Fuentes , Merlo Luca 
Published: January 2025

AbstractA model is presented where a GeV axion‐like‐particle (ALP) is predicted in a large portion of the parameter space due to the presence of explicit Peccei–Quinn (PQ) symmetry‐breaking terms in an exotic leptonic sector. The latter provides a solution to the muon anomaly, within the framework of the Linear Seesaw neutrino mechanism. The spectrum is extended by a complex scalar singlet only transforming under the PQ symmetry, which generates the ALP. Its couplings with fermions can continuously span over many orders of magnitude, which constitutes a specific feature of this model in contrast to generic ultraviolet constructions. Interestingly, these couplings are suppressed by the ALP characteristic scale that can be as low as the TeV scale, which represents a novel feature of the model and opens up to several phenomenological consequences.
Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single‐cell RNA sequencing analyses
Authors: Tzec‐Interián Jorge A. , González‐Padilla Daianna , Góngora‐Castillo Elsa B. 
Published: January 2025

AbstractThe transcriptome, the complete set of RNA molecules within a cell, plays a critical role in regulating physiological processes. The advent of RNA sequencing (RNA‐seq) facilitated by Next Generation Sequencing (NGS) technologies, has revolutionized transcriptome research, providing unique insights into gene expression dynamics. This powerful strategy can be applied at both bulk tissue and single‐cell levels. Bulk RNA‐seq provides a gene expression profile within a tissue sample. Conversely, single‐cell RNA sequencing (scRNA‐seq) offers resolution at the cellular level, allowing the uncovering of cellular heterogeneity, identification of rare cell types, and distinction between distinct cell populations. As computational tools, machine learning techniques, and NGS sequencing platforms continue to evolve, the field of transcriptome research is poised for significant advancements. Therefore, to fully harness this potential, a comprehensive understanding of bulk RNA‐seq and scRNA‐seq technologies, including their advantages, limitations, and computational considerations, is crucial. This review provides a systematic comparison of the computational processes involved in both RNA‐seq and scRNA‐seq, highlighting their fundamental principles, applications, strengths, and limitations, while outlining future directions in transcriptome research.
Effect of fertilizer–air‐coupled drip irrigation on soil microbial carbon and nitrogen cycling functions
Authors: Ma Jiaying , Wen Yue , Ma Zhanli , Liu Jian , Wei Chilin , Zhang Jingzhu , Wang Zhenhua 
Published: January 2025

AbstractTo mitigate water shortages, mulched drip irrigation disrupts soil‐air gas exchange, disturbing the balance between gas production and diffusion in the soil. This study explored the effects of nitrogen (N) application and aerated irrigation on the soil microenvironment, greenhouse gas emissions in the root zone, and processing tomato yields. The objective was to offer a theoretical framework and scientific evidence to guide fertilization practices, improve the soil microenvironment, and enhance crop productivity, especially under aerated irrigation. Two irrigation methods (non‐aerated [A0] and aerated [A1]) and two N rates (150 kg·hm⁻2 [N1] and 270 kg·hm⁻2 [N2]) were tested. Results showed that aerated irrigation increased soil organic carbon (SOC), dissolved organic carbon (DOC), total nitrogen (TN), and ammonium nitrogen (NH₄⁺‐N), while N application enriched soil nitrogen content. Both aeration and N application elevated N₂O and CH₄ emissions. Path analysis revealed that fertilization‐coupled drip irrigation indirectly influences carbon‐nitrogen cycling genes by altering soil nutrient levels, affecting greenhouse gas emissions. Soil nutrients and functional gene abundance directly impacted yield, with nitrate nitrogen (NO₃⁻‐N) showing the most substantial direct effect on processing tomato yield (direct path coefficient = −1.047***). Under A1N2 (aerated irrigation with 270 kg hm⁻2 N), soil nutrient levels improved (total carbon: 25.19 g·kg−1, SOC: 18.25 g·kg−1, DOC: 93.65 mg·kg−1, TN: 0.97 g·kg−1, NH₄⁺‐N: 2.64 mg·kg−1, and NO₃⁻‐N: 1.18 mg·kg−1), resulting in a yield of 32.05 t hm⁻2, a 23.69% increase over increase over A0N1. Aerated irrigation combined with moderate nitrogen application is recommended for sustainable production to enhance soil fertility and crop yields. However, mitigation strategies such as nitrification inhibitors or optimized irrigation schedules should be employed to minimize greenhouse gas emissions.
Cellulose‐Supported SnW(S,O)4 Bimetal Sulfo‐Oxide Catalysts for the Catalytic Reduction of Pollutants in the Dark
Authors: Liu Ben , Wu Binghong , Chen Lianghui , Zhang Xinxin , Lin Jinguo , Chen Xiaoyun 
Published: January 2025

AbstractIn this paper, cellulose‐supported SnW(S,O)4 bimetal sulfo‐oxide catalysts (labeled as SnWSO‐C or SW@C) with exceptional catalytic performance in the reduction of MB, RhB, and Cr(VI) in the presence of NaBH4 under dark conditions were synthesized via an in‐situ hydrolysis method. The cellulose‐supported catalyst system with diverse tree species of Pinus massoniana (Pm), Populus tomentosa Carrière (Ptc), Rice hull (Rh), Phyllostachys edulis (Pe) was investigated. The 100 mL solutions of MB (20 ppm), RhB (50 ppm), and Cr(VI) (50 ppm) were completely reduced by SW@Cotton, SW@Pe, SW@Rh, SW@Ptc, and SW@Pm within 10, 7, 13, 4, and 4 min for MB; 7, 7, 8, 10, and 4 min for RhB; and 5, 8, 10, 10, and 8 min for Cr(VI), respectively. Among them, SW@Pe catalyst exhibits the highest catalytic reduction efficiency and excellent stability, maintaining a removal rate of 96% after six cycles. The superior catalytic reduction performance was attributed the unique properties of Phyllostachys edulis cellulose, characterized by low crystallinity (53.25%), minimal ash content (0.15%), and the lowest degree of polymerization (1267). These features facilitated the improved dispersion of the SnWSO bimetal sulfo‐oxide, leading to smaller crystal size, lower electrochemical impedance (2.24 Ω), and a larger electrochemically active surface area (21.86 mF/cm2). This study demonstrates the potential of cellulose‐supported bimetal sulfo‐oxide catalysts for wastewater treatment, which is significant for advancing future research on environmental pollution management using biomass‐based materials.
A Comprehensive Review on the Synthesis and Therapeutic Potential of Cobalt Ferrite (CoFe2O4) Nanoparticles
Authors: Arora Kishika , Ledwani Lalita , Komal  
Published: January 2025

AbstractThe field of nanotechnology is witnessing a remarkable surge in research and applications across various domains, showcasing exponential growth. Considerable progress has been made in the advancement of novel techniques for the synthesis of magnetic nanoparticles (MNPs) with enhanced features. Within this realm, spinel nanoferrites have gained remarkable attention due to their significant characteristics, such as increased magnetic responsiveness, improved stability in biological environments, ease of synthesis, and enhanced surface modification capabilitiesmaking them highly applicable in diverse domains. Cobalt ferrite nanoparticles are considered one of the most investigated MNPs within this range. Owing to their distinct physical, chemical, and magnetic properties, CoFe₂O₄ NPs have emerged as potential candidates in the realm of biomedical applications, highlighting their suitability for innovative healthcare solutions. For a considerable period, the limited effectiveness of current cancer treatment methods such as chemotherapy and radiotherapy has posed many challenges and side effects. This prompted the need for the development of new technologies by incorporating various functional nanomaterials that showed substantial efficacy as effective strategies for treating cancer. This comprehensive review, therefore, introduces the prominent methods for synthesizing these ferrites and significant biomedical applications, particularly focusing on the anticancerand antibacterial properties exhibited by cobalt ferrite nanoparticles.
Freestanding Wide‐Bandgap Semiconductors Nanomembrane from 2D to 3D Materials and Their Applications
Authors: Kim Seung‐Il , Moon Ji‐Yun , Bae Sanggeun , Xu Zhihao , Meng Yuan , Park Ji‐Won , Lee Jae‐Hyun , Bae Sang‐Hoon 
Published: January 2025

AbstractWide‐bandgap semiconductors (WBGS) with energy bandgaps larger than 3.4 eV for GaN and 3.2 eV for SiC have gained attention for their superior electrical and thermal properties, which enable high‐power, high‐frequency, and harsh‐environment devices beyond the capabilities of conventional semiconductors. Pushing the potential of WBGS boundaries, current research is redefining the field by broadening the material landscape and pioneering sophisticated synthesis techniques tailored for state‐of‐the‐art device architectures. Efforts include the growth of freestanding nanomembranes, the leveraging of unique interfaces such as van der Waals (vdW) heterostructure, and the integration of 2D with 3D materials. This review covers recent advances in the synthesis and applications of freestanding WBGS nanomembranes, from 2D to 3D materials. Growth techniques for WBGS, such as liquid metal and epitaxial methods with vdW interfaces, are discussed, and the role of layer lift‐off processes for producing freestanding nanomembranes is investigated. The review further delves into electronic devices, including field‐effect transistors and high‐electron‐mobility transistors, and optoelectronic devices, such as photodetectors and light‐emitting diodes, enabled by freestanding WBGS nanomembranes. Finally, this review explores new avenues for research, highlighting emerging opportunities and addressing key challenges that will shape the future of the field.
Rapid Amplification and Detection of Single‐Stranded Nucleic Acids for Point‐of‐Care Diagnosis
Authors: Fu Jinglin , Zhang Qiaochu , Liu Shiming , Puyat Derek , Shah Akshay , Ebrahimimojarad Alireza , Oh Sung Won 
Published: January 2025

AbstractNucleic acid detection plays a crucial role in various applications, including disease diagnostics, research development, food safety, and environmental health monitoring. A rapid, point‐of‐care (POC) nucleic acid test can greatly benefit healthcare system by providing timely diagnosis for effective treatment and patient management, as well as supporting diseases surveillance for emerging pandemic diseases. Recent advancements in nucleic acids technology have led to rapid assays for single‐stranded nucleic acids that can be integrated into simple and miniaturized platforms for ease of use. In this review, the study focuses on the developments in isothermal amplification, nucleic acid hybridization circuits, various enzyme‐based signal reporting mechanisms, and detection platforms that show promise for POC testing. The study also evaluates critical technical breakthroughs to identify the advantages and disadvantages of these methods in various applications.
Experimental study on shear bearing capacity of Ultra‐high performance concrete bent cap with thin‐walled hollow section
Authors: Lv Wenshu , Jia Junfeng , Yao Xiaofei , Zhang Kaidi , Gu Ranxing , Lai Menggang 
Published: January 2025

AbstractCompared with precast bent caps, high‐performance precast bent caps are shorter and lighter, a well‐designed precast bent cap can improve the construction rate, and guarantee an acceptable shear resistance capacity. Therefore, an ultra‐high‐performance concrete (UHPC) with a thin‐walled hollow bent cap suitable for short and medium spans was designed, and its mechanical performance was studied. Firstly, a UHPC bent cap model with a scale ratio of 1:3 was cast and used in a 4‐point loading test, and its crack propagation pattern, shear resistance capacity, and failure mode of the bent cap were revealed. Then, based on an ABAQUS finite element model verified by the experimental results, the influence of various design parameters on the shear performance of the UHPC bent cap was fully investigated, including longitudinal reinforcement ratio, stirrup ratio, web width, bottom thickness, and the thickness of the top and bottom plates. Finally, a prediction formula of shear bearing capacity suitable for different cross‐section types was developed based on the truss‐arch model. The results indicated that the bridging effect of steel fibers and diaphragm cloud restrained the generation and extension of cracks during the loading process, thus the UHPC bent cap showed good deformability and shear‐resistant capacity. Besides, the shear resistance capacity was improved by the increasing longitudinal reinforcement ratio, stirrup ratio, web width, and the thickness of the top and bottom plates. The accuracy and generalization ability of the established formula was validated by comparing the predicted results with the experimental results derived from this paper and relevant studies. The research can facilitate the application of UHPC and structure lightweight technology in bridge engineering.
Sustaining Rural Livelihoods Through Participatory Water Governance: A Review of Community‐Driven Water Resource Management Models in East and Central Africa
Authors: Lema Meserecordias Wilfred 
Published: January 2025

ABSTRACTThis study reviews experiences across East and Central Africa testing community‐driven arrangements for adaptively managing water resources according to local needs through participatory ownership and inclusive decision‐making, empowering rural water users. An extensive database search identified 100 peer‐reviewed publications related to community‐driven water governance models, and the reviewed literature was analyzed and synthesized to develop an understanding of the topic. This research has revealed a total of nine common community‐driven water resource management models implemented in the East and Central African countries: water user associations (WUAs), water user committees (WUCs), catchment management committees (CMCs), wetland management committees (WMCs), co‐management models (CMMs), integrated community structures (ICSs), NGO‐facilitated models, indigenous water management institutions (IWMIs), and faith‐based organization models (FBOMs). It was also established that these models possess several common aspects, namely, prioritizing high levels of community engagement and democratic governance and ensuring local representation in decision‐making processes. However, these models were found to exhibit distinct differences across several dimensions in that some of them focused on broader management issues, that is, water management associations, while other focused on specific water use issues, that is, WMCs. Key characteristics for the success of various models were identified to be community engagement, local knowledge integration, inclusivity, collaboration among stakeholders, conflicts resolution mechanism, as well as and funding and resources mobilization. WUAs and ICSs were found to be the best models of all. Key lessons for strengthening community‐driven water resource management models in East and Central Africa include empowering communities as stewards, investing in their capacities, fostering multisectoral collaboration, and formulating guidelines on equitable benefit‐sharing.