bluuebunny/crossref_metadata_2025_split huggingface dataset:
Implementation of the SIMPL (Society for Improving Medical Professional Learning) performance assessment tool in the emergency department: A pilot study
Authors: Haas Mary R. C. , Davis Mallory G. , Harvey Carrie E. , Huang Rob , Scott Kirstin W. , George Brian C. , Wnuk Gregory M. , Burkhardt John 
Published: February 2023

AbstractBackgroundFeedback and assessment are difficult to provide in the emergency department (ED) setting despite their critical importance for competency‐based education, and traditional end‐of‐shift evaluations (ESEs) alone may be inadequate. The SIMPL (Society for Improving Medical Professional Learning) mobile application has been successfully implemented and studied in the operative setting for surgical training programs as a point‐of‐care tool that incorporates three assessment scales in addition to dictated feedback. SIMPL may represent a viable tool for enhancing workplace‐based feedback and assessment in emergency medicine (EM).MethodsWe implemented SIMPL at a 4‐year EM residency program during a pilot study from March to June 2021 for observable activities such as medical resuscitations and related procedures. Faculty and residents underwent formal rater training prior to launch and were asked to complete surveys regarding the SIMPL app's content, usability, and future directions at the end of the pilot.ResultsA total of 36/58 (62%) of faculty completed at least one evaluation, for a total of 190 evaluations and an average of three evaluations per faculty. Faculty initiated 130/190 (68%) and residents initiated 60/190 (32%) evaluations. Ninety‐one percent included dictated feedback. A total of 45/54 (83%) residents received at least one evaluation, with an average of 3.5 evaluations per resident. Residents generally agreed that SIMPL increased the quality of feedback received and that they valued dictated feedback. Residents generally did not value the numerical feedback provided from SIMPL. Relative to the residents, faculty overall responded more positively toward SIMPL. The pilot generated several suggestions to inform the optimization of the next version of SIMPL for EM training programs.ConclusionsThe SIMPL app, originally developed for use in surgical training programs, can be implemented for use in EM residency programs, has positive support from faculty, and may provide important adjunct information beyond current ESEs.
Polymer‐based separator for all‐solid‐state batteries produced by additive manufacturing
Authors: Wudy Katrin , Sapishchuk Svitlana , Hofmann Joseph , Schmidt Jochen , Konwitschny Fabian , Töpper Hans‐Christoph , Daub Ruediger 
Published: February 2023

AbstractThe high demand for an efficient energy supply for various applications facilitates the development of innovative storage technologies like all‐solid‐state batteries in addition to novel production technologies. Compared to the conventional manufacturing process, additive manufacturing (AM) is a promising technology used for the rapid and cost‐effective production of battery components containing separators. However, AM technologies like laser‐based powder bed fusion of polymers (PBF‐LB/P) have been neglected so far. The present research aims to fill this research gap and outline a novel approach for processing polymers like polyethylene oxide (PEO) and polyvinylidene fluoride (PVDF) into separators using PBF‐LB/P. Optimal process parameters for manufacturing PVDF and PEO with PBF‐LB/P to generate homogeneous and dense layers represent the key findings of this paper and provide a deeper process understanding. The first proof of concept for producing separator layers by PBF‐LB/P in a scalable process is demonstrated as a result.
Recycling waste polyurethane from the refrigeration industry as filler inSBR/NRcomposites for industrial applications
Authors: Hiranobe Carlos Toshiyuki , Tolosa Gabrieli Roefero , de Almeida Santos Gleyson Tadeu , de Oliveira João Pedro Jenson , Budemberg Eduardo Roque , da Silva Michael Jones , Cabrera Flávio Camargo , Job Aldo Eloizo , Paim Leonardo Lataro , Torres Giovanni Barrera , dos Santos Renivaldo José 
Published: February 2023

AbstractThe refrigeration industry produces millions of tons of waste polyurethane (PU) every year, which can cause environmental damage and human health problems. This article analyzes the use of waste PU as filler in composites made of styrene butadiene rubber (SBR) and natural rubber (NR) to produce shoe soles. The interfacial interaction of said filler was evaluated by the Flory–Rehner method (swelling) using the equation developed by Lorenz–Park. The results of this evaluation were later compared with those obtained by the Mooney–Rivlin method using the data from stress–strain tests. According to the results of the tensile strength tests, the composites filled with waste PU present stress–strain curves that are like those of metallic materials that have low elastic strength but high plastic strength. Using the Lorenz–Park equation, the filled composites examined in this study exhibited values above 0.7, which means a strong filler–rubber interaction. Scanning Electron Microscopy and Fourier‐Transform Infrared Spectroscopy were used to investigate the morphology of the composites in detail.
Benzylic Alcohol Oxidation using Copper Oxide/ZincOxide/Zirconia Nanocomposite Catalysts
Authors: Mokhtar Mohamed , Panja Subir , Alshehri Abdulmohsen , Halawani Wael , Maiti Debabrata 
Published: February 2023

AbstractHerein, we have developed a nanocomposite catalyst for organic transformation. The catalysts are synthesized based on CuO/ZnO/ZrO2 materials through the coprecipitation method followed by calcination in air at 500 °C for 5 h. The physicochemical characterization using TGA, XRD, SEM and N2‐physisorption at −196 °C was carried out for all the prepared catalysts. Nanocomposite catalyst with Cu/Zn=1 : 1 showed the smallest particle size and largest surface area among all the other investigated catalysts. Under ideal reaction conditions, this new heterogenous catalyst has demonstrated its excellent efficacy for the oxidation of benzylic alcohol and can be successfully used in up to three catalytic cycles with little loss of catalytic activity.
Adaptive non‐singular fast terminal sliding mode based on prescribed performance for robot manipulators
Authors: Zhang Yue , Fang Lijin , Song Tangzhong , Zhang Ming 
Published: February 2023

AbstractA fast convergent non‐singular terminal sliding mode adaptive control law based on prescribed performance is formulated to solve the uncertainties and external disturbances of robot manipulators. First, the tracking error of robot manipulators is transformed by using the prescribed performance function, which improves the transient behaviors and steady‐state accuracy of robot manipulators. Then, a novel fast convergent non‐singular terminal sliding mode surface is brought up according to the transformed error, and the control law is derived to meet the stability requirements of robot manipulators. In practice, the upper boundary of the lumped disturbances cannot be accurately obtained. Therefore, an adaptive prescribed performance control (PPC) controller to lumped disturbances is brought up to ensure the stability and finite‐time convergence of robot manipulators. Finally, the system stability of robot manipulators is proved by the Lyapunov theorem. Simulation results and comparative analysis demonstrate the superiority and robustness of the raised strategy.
Scattering‐state solutions to the Dirac spinors with negative‐energy eigenstates in a rotating spheroid
Authors: Zhao Xin‐Jun , Tan Jun , Yang Xiao‐Feng 
Published: February 2023

AbstractBased on the work of Fu et al. (2020), we derive the rest seven scattering‐state solutions to the Dirac equation when and establish a relation between differential scattering cross‐section, , and stellar matter density, , using the long‐wave approximation. It is found that the sensitivity of average scattering cross‐sections to the change in the stellar matter density is proportional to . We find that the average scattering amplitudes , as well as average scattering cross‐sections , are independent of the masses of particles, , for four scattering states , i = 0, 1, 2 and 3, while and depend on , for the rest four scattering states, , i = 0, 1, 2 and 3. By measuring the scattering cross‐section, we can determine the density of the ellipsoid and obtain its gravitational properties. This work will be useful in understanding the properties of anti‐Dirac spinors and the physical effects in a rotating spheroid.
Evidence of item bias in a national flourishing measure for autistic youth
Authors: Ross Samantha M. , Haegele Justin A. , Anderson Kristy , Healy Sean 
Published: February 2023

AbstractFlourishing is a positive health indicator that aligns with strengths‐based perspectives and measures within autism research. Flourishing indicators were recently included in the National Survey of Children's Health (NSCH) and have been used to evidence disparities in flourishing experienced by autistic children compared to non‐autistic peers. Yet, little has been done to examine the utility of standard flourishing items for this population. This study examined the NSCH caregiver‐reported flourishing items for measurement item bias. A cross‐sectional, representative sample of autistic and non‐autistic US children aged 6–17 years (n = 41,691) was drawn from the 2018–2019 NSCH public dataset. A confirmatory factor analysis using a multiple indicators and multiple causes model (MIMIC‐CFA) was conducted to (1) test for differential item functioning (DIF; i.e., measurement bias); and (2) estimate latent mean group differences after controlling for DIF. Findings supported a 3‐factor (social competence, school motivation, and behavioral control), 10‐item model structure consistent with past literature, yet measurement bias was evident for 6 of the 10 items. Persistent group differences, after accounting for DIF and covariates, indicates that caregivers of autistic children perceive their children are experiencing meaningfully lower flourishing outcomes compared to caregivers of non‐autistic children. However, evidence of measurement bias for items related to the social competence dimension calls into question the applicability of this measure for autistic children. Further interpretation of group differences and use of this measure should be approached with caution.
Intensity enhancement of photoluminescence in Tb3+/Eu3+ co‐doped Ca14Zn6Al10O35 phosphor for WLEDs
Authors: Bhelave Samirkumar R. , Kadam Abhijeet R. , Yerpude Atul N. , Dhoble Sanjay J. 
Published: February 2023

AbstractThis article focuses on the effect of monovalent cation doping on the optical properties of rare earth (RE = Eu3+, Tb3+) co‐doped Ca14Zn6Al10O35 which has been synthesized by a low temperature combustion method. Crystalline phase of the Ca14Zn6Al10O35 phosphor was examined and confirmed by X‐ray diffraction measurement. Under near‐ultraviolet light excitation Eu3+‐doped Ca14Zn6Al10O35 phosphor exhibit characterization of Eu3+ emission bands that are located at a maximum wavelength (λmax) of approximately 470 nm and other peaks centred at 593 nm and 615 nm, respectively. With Tb3+‐doped Ca14Zn6Al10O35 phosphor showing a green emission band centred at 544 nm under near‐ultraviolet range. Furthermore, we studied the energy transfer process in Eu3+/Tb3+pair and enhancement in photoluminescence (PL) intensity with doping different charge compensation. Here we obtained the optimum PL emission intensity of the phosphor in broad and intense visible spectral range which may be significant for the fabrication of white light emitting diodes (WLEDs).
Chemical composition, antifungal and antibiofilm activities of essential oils from Glycyrrhiza foetida (Desf.) growing in Tunisia
Authors: AL‐Hmadi Hekmat B. , Majdoub Siwar , Chaabane‐Banaoues Raja , Nardoni Simona , El Mokni Ridha , Dhaouadi Hatem , Piras Alessandra , Babba Hamouda , Porcedda Silvia , Hammami Saoussen 
Published: February 2023

AbstractThis study was designated to investigate the chemical composition, the antifungal activity and antibiofilm properties of Glycyrrhiza foetida (Desf.) growing in Tunisia and recognized for its pharmacological and therapeutic effects. The chemical analysis of essential oil samples prepared via hydrodistillation of the aerial parts was performed by gas chromatography–mass spectrometry (GC–MS). Moreover, the antifungal activity of G. foetida essential oil was developed against three dermatophyte strains, two molds and Candida spp. yeasts using the broth microdilution assay. According to the percentages, the main constituents are δ‐cadinene (13.9%), (E)‐caryophyllene (13.2%) and γ‐cadinene (8.3%). The efficiency of the essential oil in inhibiting Candida albicans biofilms formation was also evaluated in terms of inhibitory percentages. The results showed that C. albicans and Microsporum canis were the most sensitive to G. foetida essential oil with a complete inhibition at 0.4 and 0.2 mg ml−1, respectively. Candida albicans biofilm development was reduced by 80% by the volatile oil at a concentration of 0.8 mg ml−1. The essential oil of G. foetida has a promising role in the control of fungal agents with medical interest and in inhibition of Candida biofilm development.
Studies of Cytotoxicity Effects, SARS‐CoV‐2 Main Protease Inhibition, and in Silico Interactions of Synthetic Chalcones
Authors: Guterres Fernandes Octavio L. , Tizziani Tiago , Dambrós Bibiana P. , Ferreira de Sousa Natália , Mansur Pontes Carime L. , da Silva Layzon A. L. , Escorteganha Pollo Luiz A. , de Assis Francisco F. , Scotti Marcus T. , Scotti Luciana , Braga Antonio L. , Steindel Mario , Sandjo Louis P. 
Published: February 2023

AbstractSARS‐CoV‐2 main protease (Mpro) plays an essential role in proteolysis cleavage that promotes coronavirus replication. Thus, attenuating the activity of this enzyme represents a strategy to develop antiviral agents. We report inhibitory effects against Mpro of 40 synthetic chalcones, and cytotoxicity activities, hemolysis, and in silico interactions of active compounds. Seven of them bearing a (E)‐3‐(furan‐2‐yl)‐1‐arylprop‐2‐en‐1‐one skeleton (10, 28, and 35–39) showed enzyme inhibition with IC50 ranging from 13.76 and 36.13 μM. Except for 35 and 36, other active compounds were not cytotoxic up to 150 μM against THP‐1 and Vero cell lines. Compounds 10, and 35–39 showed no hemolysis while 28 was weakly hemotoxic at 150 μM. Moreover, molecular docking showed interactions between compound 10 and Mpro (PDBID 5RG2 and 5RG3) with proximity to cys145 and His41, suggesting a covalent binding. Products of the reaction between chalcones and cyclohexanethiol indicated that this binding could be a Michael addition type.
Determination of Bacterial Diversity of Propolis Microbiota
Authors: Ersoy Omeroglu Esra , Keriman Arserim‐Uçar Dılhun , Yegin Zeynep , Çağlayan Nevzat , Nur Zafer Yurt Mediha , Busra Tasbasi Behiye , Esma Acar Elif , Ucak Samet , Cengiz Ozalp Veli , Sudagidan Mert 
Published: February 2023

AbstractPropolis is a natural resinous mixture produced by the excretions of honeybees. PCR amplification of the 16S rRNA gene region was achieved using DNA of pre‐enriched propolis samples collected from Apis mellifera production hives (n=37) in Eastern Türkiye (Bingöl and its regions). Next‐generation sequencing and metabarcoding techniques were used to identify bacterial communities in propolis samples. Firmicutes dominated the phylum structure, with Proteobacteria, Actinobacteria, Tenericutes, and Spirochaetes following. The top three bacterial families were Bacillaceae, Enterobacteriaceae, and Enterococcaceae. Bacillus (dominantly B. badius and B. thermolactis at the species level) was recognized at the genus level, followed by Enterococcus and Clostridium sensu stricto. Our study comprehensively identified the bacterial diversity of propolis samples. Further investigations targeting to enlighten the microbiota of propolis and its potential application fields are required to gain better insight into ecological, nutritional, and medicinal perspectives.
Anti‐Inflammatory Activities of Monoterpene and Sesquiterpene Glycosides from the Aqueous Extract of Artemisia annua L.
Authors: Wu Qi‐Guo , Huang Le‐Yi , Fan Ming‐Hui , Chou Gui‐Xin , Wang Yong‐Li 
Published: February 2023

AbstractArtemisia annua L. is a Chinese medicinal herb, but the origin of its pharmacological properties, including its anti‐inflammatory activity, remain unknown. In this study, five new monoterpene glycosides (1–5) and two new sesquiterpene glycosides (6 and 7) were isolated from the aqueous extract of the aerial parts of A. annua. The structures of these glycosides were determined using high‐resolution electrospray ionization mass spectrometry, nuclear magnetic resonance spectroscopy, electronic circular dichroism calculations, and chemical hydrolysis methods. The anti‐inflammatory activities of the isolated compounds were evaluated by down‐regulating interleukin‐6 (IL‐6) in lipopolysaccharide‐stimulated RAW 264.7 macrophages. Notably, all the new compounds significantly inhibited the expression of IL‐6 in a dose‐dependent manner.
Impact of lesion length on the outcomes of chronic total occlusion percutaneous coronary intervention: Insights from the PROGRESS‐CTO registry
Authors: Rempakos Athanasios , Simsek Bahadir , Kostantinis Spyridon , Karacsonyi Judit , Choi James W. , Poommipanit Paul , Khatri Jaikirshan J. , Jaber Wissam , Rinfret Stephane , Nicholson William , Gorgulu Sevket , Jaffer Farouc A. , Chandwaney Raj , Koutouzis Michael , Tsiafoutis Ioannis , Alaswad Khaldoon , Krestyaninov Oleg , Khelimskii Dmitrii , Karmpaliotis Dimitrios , Uretsky Barry F. , Patel Mitul P. , Mahmud Ehtisham , Potluri Srinivasa , Rangan Bavana V. , Mastrodemos Olga C. , Allana Salman , Sandoval Yader , Burke Nicholas M. , Brilakis Emmanouil S. 
Published: February 2023

AbstractBackgroundThe impact of occlusion length on the procedural techniques and outcomes of chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has received limited study.MethodsWe examined the clinical and angiographic characteristics and procedural outcomes of 10,335 CTO PCIs at 42 US and non‐US centers between 2012 and 2022. The cohort was divided into two groups based on lesion length (≥20 mm vs. <20 mm).ResultsLong lesions were present in 7208 (70%) patients. Comorbidities were more common in patients with long CTOs. Compared with short lesions, long lesions had higher J‐CTO score (2.8 ± 1.1 vs. 1.3 ± 1; p < 0.001) and retrograde wiring was more often the initial (15.5% vs. 4.0%; p < 0.001) and successful (22.8% vs. 8.2%; p < 0.001) crossing strategy. Long lesions were more likely to require longer procedure (123 vs. 91 min; p < 0.001) and fluoroscopy (47.1 vs. 32.2 min; p < 0.001) time, larger contrast volume (218 vs. 200 mL; p < 0.001) and higher air kerma radiation dose (2.4 vs. 1.7 Gy; p < 0.001). After adjusting for potential confounders, long lesions were associated with lower technical success (odds ratio [OR]: 0.91 per 10 mm increase; 95% confidence interval [CI]: 0.88, 0.94) and higher major adverse cardiovascular events (MACE) (OR: 1.08 per 10 mm increase; 95% CI: 1.02, 1.15).ConclusionsCTO PCI of long occlusions is independently associated with lower rates of technical success and higher rates of in‐hospital MACE.
Malignant transformation of tailgut cyst to squamous cell carcinoma, a rare case with poor outcome
Authors: Moshtaghian Mahsa , Shahsiah Reza , Jafari Fatemeh , Aghili Mahdi 
Published: February 2023

AbstractTailgut cyst, a type of retro‐rectal cyst, is a rare condition requiring evaluation for malignant transformation. We report a case of squamous cell carcinoma arising in the retro‐rectal cyst, in a 51‐year‐old female who underwent incomplete resection of the cyst and chemo‐radiotherapy, subsequently became locally recurred and metastatic.
Defensive information processing and nonadherence to health‐protective behaviors
Authors: Green Beverly Beth 
Published: February 2023

Plain language summary

In this issue of Cancer, Clarke et al. measure defensive information processing (DIP) to avoid fecal immunochemical testing for colorectal cancer.

DIP is a way of reducing the negative psychological effects of threats such as cancer and may influence health‐protective behaviors such as the completion of recommended cancer screening.

This editorial complements Clarke et al.’s study with a discussion of interventions for decreasing DIP around cancer screening and other health‐protective recommendations.
The role of defensive information processing in population‐based colorectal cancer screening uptake
Authors: Clarke Nicholas , Hayes Louise , McQueen Amy , Gallagher Pamela , Kearney Patricia M. , McNamara Deirdre , O’Morain Colm A. , von Wagner Christian , Mooney Therese , Sharp Linda 
Published: February 2023

AbstractBackgroundInternationally, colorectal cancer screening participation remains low despite the availability of home‐based testing and numerous interventions to increase uptake. To be effective, interventions should be based on an understanding of what influences individuals’ decisions about screening participation. This study investigates the association of defensive information processing (DIP) with fecal immunochemical test (FIT)–based colorectal cancer screening uptake.MethodsRegression modeling of data from a cross‐sectional survey within a population‐based FIT screening program was conducted. The survey included the seven subdomains of the McQueen DIP measure. The primary outcome variable was the uptake status (screening user or nonuser). Multivariable logistic regression was used to estimate the odds ratio (OR) for screening nonuse by DIP (sub)domain score, with adjustments made for sociodemographic and behavioral factors associated with uptake.ResultsHigher scores (equating to greater defensiveness) on all DIP domains were significantly associated with lower uptake in the model adjusted for sociodemographic factors. In the model with additional adjustments for behavioral factors, the suppression subdomains of “deny immediacy to be tested” (OR, 0.53; 95% confidence interval [CI], 0.43–0.65; p < .001) and “self‐exemption” (OR, 0.80; 95% CI, 0.68–0.96; p < .001) independently predicted nonuse of FIT‐based screening.ConclusionsThis is the first study outside the United States that has identified DIP as a barrier to colorectal cancer screening uptake, and it is the first focused specifically on FIT‐based screening. The findings suggest that two suppression barriers, namely denying the immediacy to be tested and self‐exempting oneself from screening, may be promising targets for future interventions to improve uptake.