bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of the institutional model on psychiatric patients in Chile from the 19th to 21st centuries: a scoping review
Authors: Vivaldi Macho Ennio , Gomez Barbieri Gustavo , Lechuga Hernán , Soto-Suazo Mauricio 
Published: September 2023

IntroductionVarious mental health hospital models have been tested in Chile since its foundation. The institutional model with the Asylum and the Madhouse prevailed during the nineteenth century and much of the twentieth. But is deinstitutionalizing all psychiatric patients the solution?Evidence acquisitionA PubMed, Epistemonikos, Lilacs, and Google Scholar Scoping Review was carried out in the last 5 years using the PRISMA-P method and the Scoping review search strategy. The MeSH terms (“Psychiatry/history” AND “Chile”) OR (“Mental disorders” AND “therapy”) were used during the search. Finally, papers focused on clinical trial therapy evaluation were excluded, and we emphasized the effects of historical evidence.Evidence synthesisWe identified 35 primary studies, and we counted the number of articles included in the review that potentially met our inclusion criteria and noted how many studies had been missed by our search. We analyzed 10 primary studies and 10 primary historical resources that were included in this study.ConclusionThe state must become a guarantor and be responsible for its psychiatric patients and provide professional and humanitarian support to its patients, be it through community psychiatry, day hospitals, devices such as mental health clinics, or psychiatric institutes dedicated to teaching and research. Patients should not be left to the free will of their direct relatives, but rather the state should strengthen the primary care system.
Exploring views and experiences of the general public’s adoption of digital technologies for healthy lifestyle in Singapore: a qualitative study
Authors: Roystonn Kumarasan , AshaRani P. V. , Devi Fiona , Wang Peizhi , Zhang Yunjue , Jeyagurunathan Anitha , Abdin Edimansyah , Car Lorainne Tudor , Chong Siow Ann , Subramaniam Mythily 
Published: September 2023

ObjectiveLittle is known about the general adult population’s adoption of digital technology to support healthy lifestyle, especially when they are expected to take greater personal responsibility for managing their health and well-being today. The current qualitative study intended to gain an in-depth understanding of determinants of digital technology adoption for healthy lifestyle among community-dwelling adults in Singapore.DesignA qualitative study design, with thematic framework analysis was applied to develop themes from the data.SettingSemi-structured individual interviews were conducted with participants either face-to-face or online through a videoconferencing platform.Participants14 women and 16 men from the general population who were between the ages of 22 and 71 years.ResultsThree major themes were developed: (1) digitally disempowered (2) safety and perceived risks and harm; (3) cultural values and drives. Adoption of technology among the general population is needs-driven, and contingent on individual, technological and other cross-cultural contextual factors.ConclusionOur findings highlight there is no one solution which fits all individuals, emphasizing the challenges of catering to diverse groups to reduce barriers to adoption of digital technologies for healthy lifestyle. Digital guidance and training, as well as social influences, can motivate technological adoption in the population. However, technical problems as well as data security and privacy concerns should first be adequately addressed. This study provides rich cross-cultural insights and informs policy-making due to its alignment with government public health initiatives to promote healthy lifestyle.
Examining the impact of perceived stress, anxiety, and resilience on depression among medical staff after COVID-19 quarantine: a chain mediation analysis
Authors: Chen Dongyang , Ni Yi , Lu Jiani , Wang Yiwen , Qi Qi , Zhai Hua 
Published: September 2023

IntroductionThe COVID-19 pandemic and subsequent quarantine measures have led to a significant impact on mental health worldwide. Medical staff, in particular, have been exposed to high levels of stress due to their frontline work during the crisis. However, there is still limited research on the psychological mechanism among medical staff after quarantine.MethodsIn this cross-sectional observational study, 150 medical staff from Shanghai YangZhi Rehabilitation Hospital, Shanghai, China, were enrolled in October 2022. SPSS 26.0 and PROCESS 4.0 model 6 were used to analyze the chain mediating effect of perceived stress, anxiety, resilience and depression among medical staff after quarantine. Anxiety and depression were compared during and after the quarantine. All scales have high validity and reliability in a Chinese population.ResultsOur findings revealed a positive correlation between perceived stress and anxiety (r = 0.60, p &lt; 0.001) and depression (r = 0.60, p &lt; 0.001) levels among medical staff. Conversely, resilience was found to have a negative correlation with perceived stress (r = −0.67, p &lt; 0.001), anxiety (r = −0.57, p &lt; 0.001) and depression (r = −0.61, p &lt; 0.001). The score of depression during the quarantine was higher than the score after the quarantine, but the p-value is only marginally significant (p = 0.067). The score of anxiety during the quarantine was significantly higher than the score after the quarantine (p &lt; 0.05). Moreover, the chain mediation model suggested that anxiety and resilience could mediate the association between perceived stress and depression among medical staff following quarantine. Specifically, perceived stress had no direct effect on depression (β = 0.025, t = 0.548, p = 0.59) but positively predicted anxiety (β = 0.381, t = 8.817, p &lt; 0.001) and resilience (β = −1.302, t = −6.781, p &lt; 0.001), which influenced depression levels indirectly through multiple pathways. The three indirect paths: the mediating role of anxiety, the mediating role of resilience, and the chain mediating role of both anxiety and resilience.DiscussionThis study emphasizes the importance of psychological interventions aimed at protecting medical staff’s psychological resilience and promoting coping mechanisms to manage stress during and after crises such as the COVID-19 pandemic. Additionally, our findings suggest that both anxiety and resilience play critical roles in mitigating the detrimental effects of perceived stress on mental health and further highlight the need for continued research to better understand the complex interplay of these factors.
Measuring the healthcare spatial deprivation in multiple perspectives: a case study of Ningbo city
Authors: Qian Yue , Qiao Guanmin , Li Tonglu , Ma Renfeng 
Published: September 2023

BackgroundEqualization of medical services is fundamental to the development of people-centered urbanization in Chinese-style modernization. In the past few decades, the achievements of the Chinese economy have remarkably increased the quantity and quality of healthcare services. Under rapid urbanization, large-scale population floating has led to a mismatch between supply and demand for healthcare services and raised the tension between spatial demographic reorganization and the relative stability of public healthcare service facilities. The current studies of healthcare spatial deprivation (HSD) mainly are focus on either supply, or demand, or accessibility based on census data. Therefore, it is necessary to build a multiple index that could give a physical result by using ordinary indices and mixing them together by relative methods to overcome this problem.MeasureWe chose Ningbo city, Zhejiang province, located in the eastern coastal region of China, as the study area. Moreover, from 2000 to 2020, the urbanization rate of Ningbo rapidly increased from 55.75 to 78.0%. In order to show the HSD in a rapidly urbanizing city, we first consider the subdistrict as the scale, innovatively absolve the medical accessibility to the IRD (Index of Relative Disadvantage), and construct the Index of Healthcare Relative Spatial Deprivation (IHRSD) framework. Based on the seventh national census data, we apply an IHRSD with Entropy Weight Method, 2SFCA (Two-step Floating Catchment Area Method) and GDM (Geographical Detector Model) to measure where and who are vulnerable to deprive in healthcare.ResultMeasured by IHRSD, (1) There is stronger healthcare spatial deprivation in peri-urban and developed-town in Ningbo; (2) Young childhood and fertile-women are vulnerable to healthcare spatial deprivation, in fact, they are spatially deprived in healthcare; (3) The socio-demographic attribute is a significant factor in healthcare spatial deprivation, especially the level of aging and population clustering; and (4) The relationship between healthcare spatial deprivation and accessibility shows an inverted U-shaped structure.ConclusionOur experiments show that the problems of HSD are mainly from the characteristics of the population, the layout of healthcare service institutions, the accessibility of the traffic system and the natural conditions. Although the constructions of equalization of primary medical and health services, hierarchical diagnosis, and treatment, and the “healthcare complex” are currently trying to reduce the phenomenon of HSD. Faced with groups and location, the acquisition of the accurately healthcare service supply is the key to realizing healthcare spatial equity.
Successful CAR-T cell therapy in a refractory MCL patient with bacterial, fungal and COVID-19 infection: a case report
Authors: Radici Vera , Giagulli Cinzia , Accorsi Buttini Eugenia , Farina Mirko , Polverelli Nicola , Brugnoni Duilio , Chiarini Marco , Galvagni Anna , Almici Camillo , Ferrari Emilio , Bianchetti Andrea , Masneri Stefania , Leoni Alessandro , Re Federica , Bernardi Simona , Malagola Michele , Re Alessandro , Caruso Arnaldo , Russo Domenico 
Published: September 2023

BackgroundThe COVID-19 pandemic has had a significant impact on the management and care of onco-hematological patients, particularly those with lymphoproliferative disorders who are at higher risk for COVID-19 associated bacterial and fungal superinfections.Case presentationWe present the successful treatment of a 44-year-old male patient with refractory mantle cell lymphoma treated with chimeric antigen receptor T (CAR-T) cell therapy, despite concurrent COVID-19 infection. The patient developed grade II cytokine release syndrome, requiring admission to the intensive care unit. The CAR-T cells expanded effectively, and the patient achieved complete metabolic remission. During the treatment course, the patient experienced complications including COVID-19-associated pulmonary aspergillosis and a co-infection with Stenotrophomonas maltophilia and the SARS-CoV-2 omicron variant. Prompt antifungal and antibacterial therapy, along with appropriate COVID-19 treatment, led to the resolution of these infections. Dexamethasone was also administered to reduce inflammation and aid hematologic recovery. Despite the presence of multiple infections, the patient achieved complete remission of lymphoma, highlighting the effectiveness of CAR-T cell therapy in this high-risk patient.ConclusionDespite the challenges posed by concurrent infections, the decision to proceed with CAR-T cell therapy in this patient proved to be successful, resulting in complete remission of lymphoma. Early initiation of supportive therapies and the use of dexamethasone contributed to the resolution of complications. This case underscores the importance of individualized decision-making and the potential benefits of CAR-T cell therapy in similar high-risk patients.
A clinical prediction model for predicting the surgical site infection after an open reduction and internal fixation procedure considering the NHSN/SIR risk model: a multicenter case–control study
Authors: Taherpour Niloufar , Mehrabi Yadollah , Seifi Arash , Hashemi Nazari Seyed Saeed 
Published: September 2023

IntroductionSurgical site infection (SSI) is one of the most common surgical-related complications worldwide, particularly in developing countries. SSI is responsible for mortality, long hospitalization period, and a high economic burden.MethodThis hospital-based case–control study was conducted in six educational hospitals in Tehran, Iran. A total of 244 patients at the age of 18–85 years who had undergone open reduction and internal fixation (ORIF) surgery were included in this study. Among the 244 patients, 122 patients who developed SSIs were selected to be compared with 122 non-infected patients used as controls. At the second stage, all patients (n = 350) who underwent ORIF surgery in a hospital were selected for an estimation of the standardized infection ratio (SIR). A logistic regression model was used for predicting the most important factors associated with the occurrence of SSIs. Finally, the performance of the ORIF prediction model was evaluated using discrimination and calibration indices. Data were analyzed using R.3.6.2 and STATA.14 software.ResultsKlebsiella (14.75%) was the most frequently detected bacterium in SSIs following ORIF surgery. The results revealed that the most important factors associated with SSI following an ORIF procedure were found to be elder age, elective surgery, prolonged operation time, American Society of Anesthesiologists score of ≥2, class 3 and 4 wound, and preoperative blood glucose levels of &gt;200 mg/dl; while preoperative higher hemoglobin level (g/dl) was found to be a protective factor. The evidence for the interaction effect between age and gender, body mass index and gender, and age and elective surgery were also observed. After assessing the internal validity of the model, the overall performance of the models was found to be good with an area under the curve of 95%. The SIR of SSI for ORIF surgery in the selected hospital was 0.66 among the patients aged 18–85 years old.ConclusionNew risk prediction models can help in detecting high-risk patients and monitoring the infection rate in hospitals based on their infection prevention and control programs. Physicians using prediction models can identify high-risk patients with these factors prior to ORIF procedure.
Endometrial scratching during hysteroscopy in women undergoing in vitro fertilization: a systematic review and meta-analysis
Authors: Papanikolaou Evangelos , Peitsidis Nikolaos , Tsakiridis Ioannis , Michos Georgios , Skalias Antonios , Patoulias Dimitrios , Poutoglidis Alexandros , Mamopoulos Apostolos , Athanasiadis Apostolos , Grimpizis Grigorios , Najdecki Robert 
Published: September 2023

ObjectiveEndometrial scratching (ES) during hysteroscopy before embryotransfer (ET) remains doubtable on whether it benefits the reproductive outcomes. The optimal technique is not clear and repeated implantation failure as a challenging field in in vitro fertilization (IVF) seems to be the springboard for clinicians to test its effectiveness.MethodsMedline, PMC, ScienceDirect, Scopus, CENTRAL, Google Scholar were searched from their inception up to April 2023 for studies to evaluate the effectiveness of adding endometrial scratching during hysteroscopy before ET.ResultsThe initial search yielded 959 references, while 12 eligible studies were included in the analyses, involving 2,213 patients. We found that hysteroscopy and concurrent ES before ET resulted in a statistically significant improvement in clinical pregnancy rate (CPR) [RR = 1.50, (95% CI 1.30–1.74), p &lt; 0.0001] and live birth rate (LBR) [RR = 1.67, (95% CI 1.30–2.15), p &lt; 0.0001] with no statistically significant difference on miscarriage rate [RR = 0.80 (95% CI 0.52–1.22), p = 0.30]ConclusionOur meta-analysis suggests that hysteroscopy with concurrent ES may be offered in IVF before ET as a potentially improving manipulation. Future randomized trials comparing different patient groups would also provide more precise data on that issue, to clarify specific criteria in the selection of patients.Systematic Review RegistrationPROSPERO (CRD42023414117)
Establishment and Characterization of a Spermatogonial Stem Cell Line from Tiger Puffer Fish (Takifugu rubripes)
Authors: Tan Leilei , Liu Qian , He Yangbin , Zhang Jingjing , Hou Jilun , Ren Yuqin , Ma Wenxiu , Wang Qian , Shao Changwei 
Published: September 2023

Tiger puffer fish (Takifugu rubripes) has become the main fish species cultured in China since the last century because of its high economic value. Male and female tiger puffer fish need 2 and 3 years each to reach sexual maturity, which limits the development of breeding research for this species. In recent years, in vitro culture of fish spermatogonial stem cells (SSCs) have shown potential in aquaculture. In the present study, we established a spermatogenic stem cell line from T. rubripes (TrSSCs). TrSSCs were characterized by polygonal morphology, predominantly retained 44 chromosomes, and grew rapidly at 26 °C and in L-15. TrSSCs were still able to grow stably after more than one year of in vitro culture. TrSSCs showed positive alkaline phosphatase staining. TrSSCs expressed germ cell-associated genes, including dnd, ddx4, piwil, gfra1b, sox2, myca, nanog, ly75, and dazl, as determined by semiquantitative assays, and almost all cells were found to express the germ cell genes ddx4 and gfra1b in a fluorescence in situ hybridization assay. In vitro, induction experiments demonstrated the TrSSCs possessed the ability to differentiate into other types of cells. Our research has enriched the fish spermatogonial stem cell resource bank, which will provide an efficient research model for sex determination and sex control breeding in fish, establishing a foundation for subsequent breeding research.
Negative pressure wound therapy in the treatment of purulent wounds of the maxillofacial superficial cellular spaces
Authors: Morozova M. N. , Demyanenko S. A. , Tofan Yu. V. , Dubrovina-Parus T. A. , Kukharenko A. G. 
Published: September 2023

Relevance. The choice of the method for purulent wound management (open or closed) is a relevant problem in surgery. The way of drainage is the fundamental factor of the effect on the wound. The open-drainage systems are most frequent in maxillofacial surgery, and the drain is passive, combined with various drug administration. It has significant drawbacks: the short action of the injected substances, painful dressing changes, long wound healing time, etc. The instillation drainage therapy is not widely available and is used only in clinics with appropriate equipment. Active draining (negative pressure suction drainage system) allows closed wound management. Though, it is still rarely used in maxillofacial surgery.Purpose. The study aimed to increase the effectiveness of the treatment of maxillofacial purulent wounds formed after the incision of odontogenic soft tissue purulent inflammatory processes using negative pressure wound therapy.Material and methods. The study was a comparative analysis of clinical and laboratory indicators of 303 patients with purulent wounds formed after incision of superficial cellular spaces’ abscesses and phlegmons. The patients formed two groups: the main group had negative pressure wound therapy (NPWT), and the comparison group had wound treatment with the traditional open method. NPWT methodology included the tubular drain placement into the purulent cavity formed after the incision and administration of a surgical film on the wound. The distal tube end was attached to a vacuum source that simultaneously was a canister for exudate collection and analysis. We followed up on clinical manifestations and endointoxication indicators and studied the wound content toxicity and the dynamics of the respiratory enzyme succinate dehydrogenase activity.Results. The negative pressure system appears to allow fast and atraumatic wound management, reducing the inflammatory stage of the wound healing process, promoting quick normalization of endointoxication parameters, which improves the patient’s general condition (fast resolution of the clinical signs), and the effect of vacuum-assisted closure allows avoiding secondary wound closure.Conclusion. Low-dose negative pressure provides the wound healing process with specific characteristics. Continuous exudate aspiration promotes rapid elimination of bacteria and detoxification of the wound and surrounding tissues, normalization of endointoxication parameters, provides anti-oedematous and analgesic effects, early restoration of impaired functions, and the time of wound healing process reaches that of healing by primary tension, which allows us to reduce the number of medications, as well as treatment and rehabilitation time.
Volcanism and Deep Structures of the Moon
Authors: Zhao Jiannan , Qiao Le , Zhang Feng , Yuan Yuefeng , Huang Qian , Yan Jianguo , Qian Yuqi , Zou Yongliao , Xiao Long 
Published: September 2023

Volcanism is the most important endogenic geological process of the Moon, which is closely related to its internal structure and thermal history. Lunar volcanism is one of the most important topics for lunar science and explorations. Recent lunar orbital observations, in situ explorations, and sample return missions have returned a new generation of high-resolution datasets, which greatly enriched our knowledge of lunar volcanism. Here, we summarize recent advances in the duration and spatial distribution of lunar mare volcanism, as well as origin of volcanic landforms such as lava flows, sinuous rilles, lava tubes, domes, and cones. We proposed several outstanding problems in the study of temporal and spatial span of lunar volcanism, the formation mechanism of the varied volcanic landforms, and their relation with deep structures. To solve these problems, more in situ explorations and sample return missions from various volcanic units are needed.
Etika Pemasaran Bank Syariah
Authors: Nurlina Nurlina 
Published: September 2023

Abstract.
Ethics is part of humans and also an important part in the marketing of Islamic banking. This paper examines marketing ethics in Islamic banking with a literature study. The aim is to provide a global explanation of the marketing ethics of Islamic banks. This study uses a type of qualitative research method with a reference-based approach that focuses on text reviews and literature reviews. The results of this study indicate that Islamic banking has many marketing ethics. Such as promoting products with soft words, marketing that is done well, professionalism, integrity, transparency, placing customers as partners, and emulating the Prophet Muhammad in all life activities.

Keywords: Islamic Ethics, Marketing, Islamic Banks
Pengaruh Realisasi Belanja Daerah Dan Upah Minimum Terhadap Tingkat Pengangguran Di Provinsi Lampung Dalam Perspektif Ekonomi Islam
Authors: RAHMAN TAUFIQUR 
Published: September 2023

Abstrak
Pengangguran menjadi salah satu masalah yang berpengaruh terhadap kesejahteraan masyarakat dan perekonomian Indonesia. Salah satunya permasalahan ketenagakerjaan ialah ketidakseimbangan antara permintaan tenaga kerja dan penawaran tenaga kerja. Penelitian ini bertujuan untuk menganalisis pengaruh realisasi Belanja Daerah dan Upah Minimum terhadap tingkat pengangguran di provinsi Lampung dalam perspektif ekonomi islam secara parsial dan keseluruhan. Penelitian ini merupakan penelitian kuantitatif menggunakan teknik analisis regresi linier berganda dengan data Times series dan diolah menggunakan program Eviews 10. Hasil penelitian ini secara keseluruhan (uji F) Belanja Daerah dan Upah Minimum berpengaruh positif dan signifikan terhadap tingkat pengangguran di Provinsi Lampung. Secara parsial (uji T) variabel Belanja Daerah berpengaruh negatif dan signifikan terhadap tingkat pengangguran, variabel Upah Minimuum berpengaruh positif dan tidak signifikan terhadap tingkat pengangguran di Provinsi Lampung, Dalam penelitian ini jika ditinjau menurut perspektif ekonomi islam, Tujuan ekonomi Islam adalah untuk mencapai falah yang direalisasikan melalui optimalisasi maslahat bagi seluruh masyarakat melalui realisasi Belanja Daerah dan Upah Minimum yang ada di provinsi Lampung sesuai perintah Allah SWT.
Kata kunci: Belanja Daerah; Upah Minimum; Pengangguran