bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of using picture books in mathematics teaching and learning: A systematic literature review from 2000–2022
Authors: Zhang Qiaoping , Sun Jin , Yeung Wing‐ying 
Published: January 2023

AbstractUsing picture books in teaching is a popular trend in early childhood education. However, little attention has been paid to such pedagogy in mathematics learning. For this article, we reviewed 16 empirical studies from the past two decades (2000–2022) regarding the use of picture books in mathematics instruction, in order to investigate their effects on mathematics learning in students. We analyse and critically assess approaches used to integrate picture books into mathematics instruction, the overall effects of such integration on the mathematical performance of students, and the factors that inhibit or enhance these effects. The findings of our review reveal that most of the selected studies targeted early mathematics education, with only a minority addressing secondary education. Various approaches are available for the integration of picture books into mathematics teaching, having various positive effects on student attitudes toward mathematics, as well as their academic performance and mathematical representation ability. The reported inhibiting factors for teachers using picture books in teaching included a lack of pedagogical knowledge and confidence, time constraints, resource constraints and doubts regarding the expected outcomes. Conversely, the enhancing factors included early educational stage (especially the pre‐school level), perceived pedagogical benefits, desire to improve teaching and enabling social norms. Suggestions for future research focused on the integration of picture books into classroom teaching are also discussed.
Growing platforms within platforms: How platforms manage the adoption of complementor products in the presence of network effects?
Authors: Agarwal Shiva , Miller Cameron D. , Ganco Martin 
Published: January 2023

AbstractResearch SummaryPlatform owners often use endorsements to actively manage complementor firms. We argue that the direct network effects of complementors' products play a central role in the platform management by its owner. We test our predictions using data on the Apple's promotion of apps. We find that apps with network effects are more likely to receive an award. This likelihood increases when the app is introduced by a developer with a larger market share but declines when introduced in a concentrated segment. The likelihood decreases further if the app is introduced in a concentrated segment by a developer that holds a larger market share. Further, we observe that in concentrated segments, the “challenger” developer has a higher likelihood of receiving the award relative to the leader.Managerial SummaryMany products offered through platforms have their own direct network effects. The value of the product for each user grows with the number of other consumers using the product. Many platform owners also actively manage their platforms to ensure platform growth and often use less traditional tools such as product endorsements to achieve this goal. In the context of video games listed in the iOS App Store and the Editors' Choice Awards as a form of product endorsement, we examine the tradeoffs that products with direct network effects (i.e., multiplayer video games) present to the platform owner (Apple). On the one hand, the platform owner may want to promote apps with direct network effects to help them achieve a momentum in terms of user growth. On the other hand, networked apps may become dominant in the segment with negative implications for future growth of the segment and the platform owner's profitability. We find evidence consistent with this tension and find that it critically depends on the complementor strength and market segment concentration. We also observe that in concentrated segments, the “challenger” developer has a higher likelihood of receiving the award relative to the leader.
Wide‐Field Three‐Dimensional Depth‐Invariant Cellular‐Resolution Imaging of the Human Retina
Authors: Lee ByungKun , Jeong Sunhong , Lee Joosung , Kim Tae Shik , Braaf Boy , Vakoc Benjamin J. , Oh Wang‐Yuhl 
Published: January 2023

AbstractThree‐dimensional (3D) cellular‐resolution imaging of the living human retina over a large field of view will bring a great impact in clinical ophthalmology, potentially finding new biomarkers for early diagnosis and improving the pathophysiological understanding of ocular diseases. While hardware‐based and computational adaptive optics (AO) optical coherence tomography (OCT) have been developed to achieve cellular‐resolution retinal imaging, these approaches support limited 3D imaging fields, and their high cost and intrinsic hardware complexity limit their practical utility. Here, this work demonstrates 3D depth‐invariant cellular‐resolution imaging of the living human retina over a 3 × 3 mm field of view using the first intrinsically phase‐stable multi‐MHz retinal swept‐source OCT and novel computational defocus and aberration correction methods. Single‐acquisition imaging of photoreceptor cells, retinal nerve fiber layer, and retinal capillaries is presented across unprecedented imaging fields. By providing wide‐field 3D cellular‐resolution imaging in the human retina using a standard point‐scan architecture routinely used in the clinic, this platform proposes a strategy for expanded utilization of high‐resolution retinal imaging in both research and clinical settings.
Urchin‐Like Structured MoO2/Mo3P/Mo2C Triple‐Interface Heterojunction Encapsulated within Nitrogen‐Doped Carbon for Enhanced Hydrogen Evolution Reaction
Authors: Xiao Jiamin , Zhang Shishi , Sun Yanyan , Liu Xuetao , He Guangling , Liu Heng , Khan Javid , Zhu Yanlin , Su Yaqiong , Wang Shuangyin , Han Lei 
Published: January 2023

AbstractThe development of highly efficient and cost‐effective hydrogen evolution reaction (HER) catalysts is highly desirable to efficiently promote the HER process, especially under alkaline condition. Herein, a polyoxometalates‐organic‐complex‐induced carbonization method is developed to construct MoO2/Mo3P/Mo2C triple‐interface heterojunction encapsulated into nitrogen‐doped carbon with urchin‐like structure using ammonium phosphomolybdate and dopamine. Furthermore, the mass ratio of dopamine and ammonium phosphomolybdate is found critical for the successful formation of such triple‐interface heterojunction. Theoretical calculation results demonstrate that such triple‐interface heterojunctions possess thermodynamically favorable water dissociation Gibbs free energy (ΔGH2O) of ‐1.28 eV and hydrogen adsorption Gibbs free energy (ΔGH*) of ‐0.41 eV due to the synergistic effect of Mo2C and Mo3P as water dissociation site and H* adsorption/desorption sites during the HER process in comparison to the corresponding single components. Notably, the optimal heterostructures exhibit the highest HER activity with the low overpotential of 69 mV at the current density of 10 mA cm−2 and a small Tafel slope of 60.4 mV dec−1 as well as good long‐term stability for 125 h. Such remarkable results have been theoretically and experimentally proven to be due to the synergistic effect between the unique heterostructures and the encapsulated nitrogen‐doped carbon.
Application of Nanomaterials in Stem Cell‐Based Therapeutics for Cardiac Repair and Regeneration
Authors: Qiu Jie , Liu Xiang‐Ju , You Bei‐An , Ren Na , Liu Hong 
Published: January 2023

AbstractCardiovascular disease is a leading cause of disability and death worldwide. Although the survival rate of patients with heart diseases can be improved with contemporary pharmacological treatments and surgical procedures, none of these therapies provide a significant improvement in cardiac repair and regeneration. Stem cell‐based therapies are a promising approach for functional recovery of damaged myocardium. However, the available stem cells are difficult to differentiate into cardiomyocytes, which result in the extremely low transplantation efficiency. Nanomaterials are widely used to regulate the myocardial differentiation of stem cells, and play a very important role in cardiac tissue engineering. This study discusses the current status and limitations of stem cells and cell‐derived exosomes/micro RNAs based cardiac therapy, describes the cardiac repair mechanism of nanomaterials, summarizes the recent advances in nanomaterials used in cardiac repair and regeneration, and evaluates the advantages and disadvantages of the relevant nanomaterials. Besides discussing the potential clinical applications of nanomaterials in cardiac therapy, the perspectives and challenges of nanomaterials used in stem cell‐based cardiac repair and regeneration are also considered. Finally, new research directions in this field are proposed, and future research trends are highlighted.
Engineering Second‐Order Corner States in 2D Multiferroics
Authors: Bai Yingxi , Mao Ning , Li Runhan , Dai Ying , Huang Baibiao , Niu Chengwang 
Published: January 2023

AbstractThe understanding and manipulate of the second‐order corner states are central to both fundamental physics and future topotronics applications. Despite the fact that numerous second‐order topological insulators (SOTIs) are achieved, the efficient engineering in a given material remains elusive. Here, the emergence of 2D multiferroics SOTIs in SbAs and BP5 monolayers is theoretically demonstrated, and an efficient and straightforward way for engineering the nontrivial corner states by ferroelasticity and ferroelectricity is remarkably proposed. With ferroelectric polarization of SbAs and BP5 monolayers, the nontrivial corner states emerge in the mirror symmetric corners and are perpendicular to orientations of the in‐plane spontaneous polarization. And remarkably the spatial distribution of the corner states can be effectively tuned by a ferroelastic switching. At the intermediate states of both ferroelectric and ferroelastic switchings, the corner states disappear. These finding not only combines exotic SOTIs with multiferroics but also pave the way for experimental discovery of 2D tunable SOTIs.
Super‐Bright Green Perovskite Light‐Emitting Diodes Using Ionic Liquid Additives
Authors: Sadhukhan Priyabrata , Kim Min Seong , Baek Sung‐Doo , Myoung Jae‐Min 
Published: January 2023

AbstractHalide perovskites have potential for use in next‐generation low‐cost, high‐efficiency, and highly color‐pure light‐emitting diodes (LED) that can be used in various applications, such as flat and flexible displays and solid‐state lighting. However, they still lag behind other mature technologies, such as organic LEDs and inorganic LEDs, in terms of performance, particularly brightness. This lag is partly due to the insulating nature of the long‐chain organic ligands used to control the perovskite‐film morphology. Herein, a 1‐butyl‐3‐methylimidazolium tetrafluoroborate ionic liquid (IL) is incorporated as a potential additive with CsPbBr3 perovskite precursors, which results in a super‐bright green perovskite light emitting diode (PeLED) achieving a peak luminance of 3.28 × 105 cd m−2 only at a bias voltage of 6 V, with a peak external quantum efficiency of 13.75%. This achievement is the outcome of multirole support from IL that simultaneously enables superior control over the perovskite‐film morphology, passivates defects, modifies the band energy levels, and prevents ion migration. Hence, this work demonstrates IL as a novel alternative additive with the potential to outperform conventional long‐chain ligands in high‐performance PeLED device fabrication.
Identifying potential stakeholders for the management of Lower Mgeta and Upper Zigi water catchments of Tanzania, East Africa
Authors: Lema Meserecordias W. , Kapinga Agnes G. 
Published: January 2023

AbstractCommunity participation in natural resources management is a basis for sustainable management of these resources. However, the question of which actors/assets within communities are more connected to the natural resources based on their knowledge, skills and talents is not well captured. This study, therefore, combines Asset Based Community Development approach and Bio‐Cultural approach, to identify influential stakeholders in the utilization of catchment resources in Upper Zigi and Lower Mngeta catchments, in the United Republic of Tanzania. Participatory rural appraisal tools; participatory bio‐physical resource mapping (PBRM) and participatory community asset mapping (PCAM) were used for data collection. Similar observations were made in both study sites, that, the most influential community assets were traditional healers, traditional dancers, hunters, Village Government, fishermen, farmers and family, and therefore, these most influential community assets should get involved in the management of catchment resources because they are true representatives of the community.
Continuous and discontinuous contact problem of a functionally graded orthotropic layer indented by a rigid cylindrical punch: Analytical and finite element approaches
Authors: Karabulut Pembe Merve , Çömez İsa 
Published: January 2023

AbstractIn this study, the continuous and discontinuous contact problems of a functionally graded (FG) orthotropic layer lying on a homogeneous and isotropic layer were investigated. The orthotropic layer was indented by a rigid cylindrical punch which was subjected to a concentrated normal force, and a homogeneous isotropic layer was firmly attached to a rigid substrate. For the analytical solution, the general expressions for the stresses and displacements were obtained in the presence of body forces by using elasticity theory and Fourier integral transforms. The continuous and discontinuous contact problems were reduced to the singular integral equations by means of boundary conditions. The system of the singular integral equations was solved using the Gauss‐Chebyshev integration formula. Then, the finite element solution of the two cases was also performed. Analytical results and numerical results (FEM) for critical load, initial separation distance, separation region in discontinuous contact, contact lengths under the punch, and contact stress distributions between the layer‐punch and layer‐layer were obtained for the dimensionless quantities.
Dateninfrastrukturen für die Gesundheitsforschung
Authors: Schickhardt Christoph , Winkler Eva , Sax Ulrich , Buchner Benedikt 
Published: January 2023

ZusammenfassungDie Rolle von Dateninfrastrukturen für die Gesundheitsforschung beschränkt sich nicht allein darauf, als Service oder Schnittstelle für den Datenaustausch zwischen Datenerzeuger:innen und -nutzer:innen zu fungieren. Die Infrastruktur ist vielmehr selbst ein Akteur im Prozess des Datenteilens, der für diesen auch entsprechend Verantwortung trägt.Dies gilt zuallererst für die Rechtmäßigkeit der Verarbeitung personenbezogener Daten. Fußt die Datenverarbeitung auf einer Einwilligung der betroffenen Person, ist auch seitens der Infrastruktur sicherzustellen, dass sämtliche Datenverarbeitungsprozesse von dieser Einwilligung erfasst sind. Stützt sich die Datenverarbeitung auf einen gesetzlichen Erlaubnistatbestand, müssen im Rahmen der Infrastruktur v. a. technische und organisatorische Maßnahmen ergriffen werden, damit ein möglichst hohes Datenschutzniveau sichergestellt ist. Zudem fällt der Infrastruktur eine Verantwortung zu, wenn es um die Umsetzung von Betroffenenrechten wie Auskunft, Berichtigung oder Löschung von Daten geht und um den Umgang mit Zufalls- und Zusatzbefunden.Die Frage, mit welchem Selbstverständnis sich Forscher:innen in Infrastrukturprojekte einbringen und in welcher Form auch privatwirtschaftliche Unternehmen in solcherlei Projekte eingebunden werden sollen, muss sich am Gemeinwohl orientieren. Damit einher geht die Verpflichtung, dass Infrastrukturen so weit wie möglich an den Prinzipien der Partizipation, der Transparenz und der Wissenschaftskommunikation ausgerichtet sind. Die Beachtung all dieser ethischen und rechtlichen Aspekte ist vor allem auch deshalb wichtig, weil nur auf diese Weise das Vertrauen aller Stakeholder gewonnen und damit die zentrale Basis für den erfolgreichen Aufbau und Betrieb einer Dateninfrastruktur geschaffen werden kann.
Traveling Waves Near Couette Flow for the 2D Euler Equation
Authors: Castro Ángel , Lear Daniel 
Published: January 2023

AbstractIn this paper we reveal the existence of a large family of new, nontrivial and smooth traveling waves for the 2D Euler equation at an arbitrarily small distance from the Couette flow in $$H^s$$

H
s

, with $$s<3/2$$

s
<
3
/
2

, at the level of the vorticity. The speed of these waves is of order 1 with respect to this distance. This result strongly contrasts with the setting of very high regularity in Gevrey spaces [see Bedrossian and Masmoudi (Publ Math Inst Hautes Etudes Sci 122:195–300, 2015)], where the problem exhibits an inviscid damping mechanism that leads to relaxation of perturbations back to nearby shear flows. It also complements the fact that there not exist nontrivial traveling waves in the $$H^{\frac{3}{2}+}$$

H

3
2

+

neighborhoods of Couette flow [see Lin and Zeng (Arch Ration Mech Anal 200:1075–1097, 2011)].
PET imaging of animal models with depressive-like phenotypes
Authors: Vazquez-Matias Daniel Aaron , de Vries Erik F. J. , Dierckx Rudi A. J. O. , Doorduin Janine 
Published: January 2023

AbstractMajor depressive disorder is a growing and poorly understood pathology. Due to technical and ethical limitations, a significant proportion of the research on depressive disorders cannot be performed on patients, but needs to be investigated in animal paradigms. Over the years, animal studies have provided new insight in the mechanisms underlying depression. Several of these studies have used PET imaging for the non-invasive and longitudinal investigation of the brain physiology. This review summarises the findings of preclinical PET imaging in different experimental paradigms of depression and compares these findings with observations from human studies. Preclinical PET studies in animal models of depression can be divided into three main different approaches: (a) investigation of glucose metabolism as a biomarker for regional and network involvement, (b) evaluation of the availability of different neuroreceptor populations associated with depressive phenotypes, and (c) monitoring of the inflammatory response in phenotypes of depression. This review also assesses the relevance of the use of PET imaging techniques in animal paradigms for the understanding of specific aspects of the depressive-like phenotypes, in particular whether it might contribute to achieve a more detailed characterisation of the clinical depressive phenotypes for the development of new therapies for depression.
Sleep disordered breathing and its relation to stroke and pulmonary hypertension in children with sickle cell disease: a single-center cross-sectional study
Authors: Tantawy Azza , El-Sherif Nayera , Makkeyah Sara , Eldeen Nahed Salah , Farghal Noura Bahaa El-Din , Soliman Nanies , Ebeid Fatma S. E. 
Published: January 2023

Abstract
Sleep disordered breathing (SDB) is a common underdiagnosed sequela of sickle cell disease (SCD) that has been linked to the frequency of vaso-occlusive crises. To determine the frequency of SDB in children with SCD and its association to SCD-related complications, thirty children and adolescents with SCD at their steady state underwent clinical, laboratory, and radiological assessment using transcranial duplex (TCD) and echo assessment of tricuspid regurge velocity (TRV). All participants had an overnight polysomnography after completing the modified STOP-Bang questionnaire. The mean age of the studied cohort was 10.2 years, with male: female ratio 1.7:1. Six children (20%) had high-risk for obstructive sleep apnea (OSA), while nine (30%) were at intermediate risk. Sleep apnea defined as apnea (AHI) > 1 event/hour was found among 18/30 (60%) subjects (14 males and 4 females). Children with AHI > 5 (moderate to severe OSA) had significantly higher TRV (p = 0.007) and left MCA flow velocity (p = 0.049) when compared to those with AHI < 5. Children with AHI > 5 were at higher risk of OSA according to the modified STOP-Bang questionnaire (p = 0.02). AHI positively correlated with TRV (r = 0.53, p = 0.003), right MCA flow velocity (r = 0.45, p = 0.013), and left MCA flow velocity (r = 0.55, p = 0.002), and negatively correlated to BMI-SDS (r =  − 0.48, p = 0.008). The high frequency of OSA in the studied cohort with SCD and its association with increasing risk of PH and TCD changes highlights the importance of early detection and management of OSA in children with SCD.
To what extent are anorectal function tests comparable? A study comparing digital rectal examination, anal electromyography, 3-dimensional high-resolution anal manometry, and transperineal ultrasound
Authors: Dekker L. , van Reijn-Baggen D. A. , Han-Geurts I. J. M. , Felt-Bersma R. J. F. 
Published: January 2023

Abstract

Background
Anorectal function tests are helpful for objective investigation of anorectal (dys)function. A variety of tests are available, but there is no recommendation when to perform which test. Furthermore, which test is the most accurate is controversial and the correlation between these tests is not very clear. The aim of our study was to examine the correlation of anal pressures and the possibility to diagnose pelvic floor dyssynergia between digital rectal examination (DRE) and several anorectal function tests.

Methods
Between January 2020 and April 2022, all men and women aged 18 to 80 years, treated at the Proctos Clinic, who were referred for pelvic floor physical therapy (PFPT) by the surgeon and underwent anorectal function tests, were included. DRE was performed to establish the anal pressure at rest and during squeeze and straining. Anorectal function tests included 3D high-resolution anal manometry (3D-HRAM), balloon expulsion test (BET), transperineal ultrasound (TPUS), and surface electromyography (s-EMG).

Results
A total of 50 patients, 37 (74%) females, were included. Median age was 51 years. Twenty-three (62%) females had a history of two or more vaginal deliveries. The most frequent reason for referral for PFPT was fecal incontinence in 27 (54%) patients. The assessed pressures and pelvic floor function measured with DRE by the surgeon and the pelvic floor physical therapist during rest, squeeze, and straining correlated in 78%, 78%, and 84%, respectively. Correlation between DRE and 3D-HRAM or s-EMG was better for squeeze pressures than resting pressures. The correlation between s-EMG and 3D-HRAM was better during squeeze than at rest with an agreement of 59% and 37%, respectively.

Conclusion
DRE by an experienced investigator is of sufficient value for daily clinical practice to detect dyssynergia and to measure sphincter tone. Commonly performed anorectal function tests correlate poorly with DRE and with other anorectal function tests. When conservative treatment fails, further investigation is warranted; however, these results should be interpreted with caution.

What does this paper add to the literature?
Anorectal function tests such as the 3D high-resolution anorectal manometry, balloon expulsion test, surface electromyography, and transperineal ultrasound are all frequently performed in the diagnostic workup in patients with defecation disorders. No previous study has compared these tests regarding their outcomes, nor has the interrater agreement been measured regarding the digital rectal examination by two experienced observers. Furthermore, transperineal ultrasound is in all probability not frequently used and therefore underexposed in the diagnostic workup of patients with dyssynergic defecation.