bluuebunny/crossref_metadata_2025_split huggingface dataset:
Culture, ethnicity, and socio‐economic status as determinants of the management of patients with advanced heart failure who need palliative care: A clinical consensus statement from the Heart Failure Association (HFA) of the ESC, the ESC Patient Forum, and the European Association of Palliative Care
Authors: Hill Loreena , Baruah Resham , Beattie James M. , Bistola Vasiliki , Castiello Teresa , Celutkienė Jelena , Di Stolfo Giuseppe , Geller Tal Prager , Lambrinou Ekaterini , Mindham Richard , McIlfatrick Sonja , Strömberg Anna , Jaarsma Tiny 
Published: July 2023

AbstractThe delivery of effective healthcare entails the configuration and resourcing of health economies to address the burden of disease, including acute and chronic heart failure, that affects local populations. Increasing migration is leading to more multicultural and ethnically diverse societies worldwide, with migration research suggesting that minority populations are often subject to discrimination, socio‐economic disadvantage, and inequity of access to optimal clinical support. Within these contexts, the provision of person‐centred care requires medical and nursing staff to be aware of and become adept in navigating the nuances of cultural diversity, and how that can impact some individuals and families entrusted to their care. This paper will examine current evidence, provide practical guidance, and signpost professionals on developing cultural competence within the setting of patients with advanced heart failure who may benefit from palliative care.
Soil–pile interaction in vertical vibration in inhomogeneous soils
Authors: Anoyatis George , François Stijn , Orakci Olgu , Tsikas Aggelos 
Published: July 2023

AbstractThis paper develops a novel reference analytical solution for axially loaded piles in inhomogeneous soils, extending the pioneering elastodynamic model of Nogami and Novak (1976) to piles embedded in vertically inhomogeneous soils. Following the classical earlier model, the pile is modelled as a rod, using the strength‐of‐materials solution, and the soil layer as an approximate continuum, which rest on rigid rock. The approximation lies in reducing the number of dependent variables by eliminating certain stresses and displacements in the governing elastodynamic equations: the vertical normal and vertical shear stresses in the soil are controlled exclusively by the vertical component of the soil displacement. Soil inhomogeneity is introduced via a power law variation of shear modulus with depth, and perfect bonding is assumed at the soil–pile interface. The proposed generalized formulation treats two types of inhomogeneity by employing pertinent eigen expansions of the dependent variables over the vertical coordinate. The response is expressed in terms of generalized Fourier series and includes: (i) displacements and stresses along the pile and the pile–soil interface; and (ii) displacement and stress in the soil. Contrary to available models for homogeneous soils, the associated Fourier coefficients are coupled, obtained as solutions to a set of simultaneous algebraic equations of equal rank to the number of modes considered.
Compositional profiling and sensory analysis of cauliflower by‐products‐enriched muffins
Authors: Tukassar Ammara , Shukat Rizwan , Iahtisham‐Ul‐Haq   , Butt Masood Sadiq , Nayik Gulzar Ahmad , Ramniwas Seema , Al Obaid Sami , Ali Alharbi Sulaiman , Ansari Mohammad Javed , Konstantinos Karabagias Ioannis , Sarwar Nazmul 
Published: July 2023

AbstractCauliflower (Brassica oleracea var. botrytis) by‐products (leaves, stems, stalks) (CBP) were successfully utilized in muffins as a model system and their feasibility of incorporation was investigated. CBP powder‐based muffin formulations were made by the progressive replacement of wheat flour (WF) with 10%, 20%, and 30% of CBP. The physicochemical, pasting properties, antioxidant potential, textural characteristics, and sensorial attributes were analyzed. Substitution of CBP significantly (p < .05) resulted in an upsurge in crude protein, crude fiber, minerals, total phenolics, and total flavonoid contents, as well as total antioxidant activity values of muffins. The pasting properties were influenced by monitoring an increase in peak, breakdown, final, and setback viscosities. Although the addition of an increasing amount of CBP improved the nutritional characteristics, however, the increased level of replacement (>10%) had significant adverse effects on baking and physical characteristics. The specific loaf volume of the developed muffins decreased the crumb color which became darker, and enriched muffins were hardened in texture. Furthermore, sensory evaluation confirmed the positive effects of CBP incorporation only up to 10%. Overall, present results highlighted that supplementation of wheat muffins with 10% CBP is a beneficial approach to enrich them with nutrients and intensify their antioxidant potential.
Operative technique: Tracheal resection and anastomosis in a revision surgery
Authors: Saetti Roberto , Ronzani Guglielmo , Meneghesso Stefano , Silvestrini Marina 
Published: July 2023

AbstractTracheal stenosis is an uncommon pathological condition in which the lumen of the trachea is reduced. Within its management an adequate preoperative workup is crucial to determine the most appropriate procedure for each patient. In this scenario tracheal resection and anastomosis is a viable approach, as a procedure in which part of the trachea is removed and then restored with a tension‐free anastomosis. It is usually indicated for extensive and high‐grade lesions or when previous endoscopic procedures had failed. The patient here presented had already undergone a balloon dilatation twice and a tracheal resection and referred to our clinic with a residual tracheal stenosis graded Myer‐Cotton 3 involving three tracheal rings. We here illustrate step‐by‐step the surgical procedure and highlight a peculiar way to perform the anastomosis, especially in a revision surgery.
Beyond employer brand content: The role of employer brand process attributes in understanding employees' reactions toward their employer
Authors: Kanwal Hira , Van Hoye Greet 
Published: July 2023

AbstractEmployees play a central role in organizational functioning and representation. HR managers thus strive to create an attractive employer image that stimulates employees' attachment and ambassadorship. However, presently, there is limited research about how employees perceive and react toward their organization's employer brand. More importantly, the studies available have focused on content attributes only (i.e., instrumental and symbolic image dimensions). This has resulted in limited (content‐based) understanding of the construct and failure to incorporate its branding‐related aspects (process attributes) which represent the crux of employer branding theory. Thus, using the HRM system strength theory and employer branding literature, this article examines three process characteristics (i.e., employer brand distinctiveness, consistency, and consensus) vis‐à‐vis instrumental and symbolic content attributes to understand employee reactions (i.e., employer attractiveness, organizational identification, and employee ambassadorship). Data were collected at two times through Prolific Academic with 254 UK and US employees. Results suggest that employer brand process attributes are valuable sources to enhance employees' identification with their organization. Moreover, distinctiveness and consistency seem especially instrumental in enhancing employees' attractiveness perceptions and display of positive ambassadorship. In addition, the process attributes explain significant incremental and unique variance beyond content attributes in employee reactions.
Plasma levels of fibrinolytic and coagulation biomarkers in HIV‐infected individuals on highly active antiretroviral therapy: A case‐control study in a Northern Ghanaian population
Authors: Derigubah Charles A. , Nkansah Charles , Mensah Kofi , Appiah Samuel K. , Osei‐Boakye Felix , Odame Enoch , Owusu Michael , Serwaa Dorcas , Hubert Maxwell A. , Bani Simon Bannison , Kuugbee Eugene , Issahaku Razak G. , Debrah Alexander Y. , Addai‐Mensah Otchere 
Published: July 2023

AbstractBackground and AimImpaired coagulation and fibrinolysis have been implicated in thromboembolism in human immunodeficiency virus (HIV)‐infected individuals. This study evaluated the plasma levels of plasminogen activator inhibitor‐1 (PAI‐1) and coagulation biomarkers in HIV‐infected individuals on highly active antiretroviral therapy (HAART).MethodsThis matched case‐control study from March to December, 2020 comprised 76 participants: 38 HIV‐positive individuals on HAART and 38 apparently healthy HIV‐negative individuals as controls. Blood samples were collected for prothrombin time (PT), activated partial thromboplastin time (aPTT), D‐dimers, PAI‐1, and soluble fibrin monomer complex (SFMC) estimations. The data were analysed using SPSS version 22.0 and statistical significance was set at p < 0.05.ResultsActivated partial thromboplastin time was significantly lower in HIV seropositive individuals on HAART compared with HIV seronegative controls (25.90 s vs. 29.0 s, p = 0.030); however, PT, SFMC, D‐dimers, and PAI‐1 were significantly higher among the HIV‐seropositive individuals compared with the controls: PT: (16.29 s ± 2.16 vs. 15.15 s ± 2.60, p = 0.010), SFMC: [8.53 ng/mL (8.03–9.12) vs. 7.84 ng/mL (7.32–8.58), p = 0.005]), D‐Dimer: [463.37 ng/mL (402.70–526.33) vs. 421.11 ng/mL (341.11–462.52), p = 0.015], and PAI‐1: [12.77 ng/mL (10.63–14.65) vs. 11.27 ng/mL (10.08–12.95), p = 0.039]. PAI‐1 showed a moderate positive correlation with D‐Dimer (r = 0.659, p < 0.001) and SFMC (r = 0.463, p = 0.003) among HIV‐positive individuals on HAART. There was a strong positive correlation between the plasma PAI‐1 concentration and the HIV viral load (r = 0.955, p < 0.001).ConclusionHIV‐seropositive individuals on HAART have deranged coagulation and fibrinolytic markers. Higher HIV viral load correlates strongly with elevated plasma levels of PAI‐1 antigens. Periodic assessment of markers of coagulation and fibrinolysis be included in the management of HIV/AIDS in Ghana.
Circ_0058063 regulates cell vitality and proliferation in oesophageal squamous‐cell carcinomas
Authors: Yang Yixuan , Zhu Bing , Ning Zhaofeng , Wang Xiaodong , Li Zhaoxia , Zhang Chunxia , Wen Linchun 
Published: July 2023

AbstractOesophageal squamous‐cell carcinoma (ESCC) is a malignant tumor of the digestive system with a poor prognosis. Recent studies have shown the promoting effect of hsa_circ_0058063 (circ_0058063) on ESCC, but the potential regulatory mechanisms of circ_0058063 in ESCC remain largely unclear. The levels of circ_0058063, microRNA‐4319 (miR‐4319) and mRNA of thrombospondin‐1 (THBS1) were indicated by quantitative real‐time polymerase chain reaction in ESCC tissues and cells. Meanwhile, the level of THBS1 was quantified by western blot analysis. In addition, the cell functions were examined by CCK8 assay, Edu assay, flow cytometry assay and transwell assay. Furthermore, the interplay between miR‐4319 and circ_0058063 or THBS1 was detected by dual‐luciferase reporter assay. Finally, an in vivo experiment was implemented to confirm the effect of circ_0058063. The level of circ_0058063 and THBS1 were increased, and the miR‐4319 level was decreased in ESCC tissues in contrast to that in normal tissues and cells. For functional analysis, circ_0058063 deficiency inhibited cell vitality, cell proliferation, migration and invasion in ESCC cells, whereas promoted cell apoptosis. Moreover, miR‐4319 was confirmed to repress the progression of ESCC cells by suppressing THBS1. In mechanism, circ_0058063 acted as a miR‐4319 sponge to regulate the level of THBS1. Besides, circ_0058063 knockdown also attenuated tumour growth in vivo. Circ_0058063 facilitates the development of ESCC through increasing THBS1 expression by regulating miR‐4319, which also offered an underlying targeted therapy for ESCC treatment.
Taxonomic studies based on leaf epidermal microanatomy using high‐resolution microscopy in Lamiaceous species and their antimicrobial effects
Authors: Ameen Fuad 
Published: July 2023

AbstractThe knowledge of essential oil antimicrobial activity of Lamiaceous species is assessed to describe its effects. The comprehensive foliar trichomes and stomatal morphology of the leaves of essential oil‐bearing plants from the family Lamiaceae revealed diverse antimicrobial properties. The aim of this study was to investigate the foliar anatomical traits of 19 Lamiaceous taxa belonging to different tribes using light and scanning electron microscopy to correctly diagnose the species. The microanatomy of the foliar epidermis, trichomes diversity, and the stomatal apertural complex was visualized. Quantitative measurements were noted to describe the variations and the qualitative aspects for example, polygonal shape epidermal cells were examined. The stomatal aperture of four types and trichomes appendages both non‐glandular and glandular was identified. Significant variation was found in both quantitative and qualitative traits, including unique ornamentation on the trichomes. The taxonomic key was constructed for accurate identification using qualitative morpho‐structural traits. The outcomes of this research explored taxonomically to accurately identify the Lamiaceous species using anatomical characters. This study will provide provides the ecological adaptation linked to evolutionary traits of leaf surfaces that evolve with time to adapt the harsh environmental conditions.Research Highlights
Investigated foliar anatomical traits of 19 Lamiaceous species
The anatomy and antimicrobial activity of essential oil yielding Lamiaceae species.
SEM revealed diverse aspects including peculiar sculptured trichomes
Microscopic identification of different stomatal complex
Biochar impacts on soil nitrogen and carbon dynamics in a Spodosol amended with biosolids and inorganic fertilizer
Authors: Lu Yanyan , Silveira Maria Lucia , Vendramini Joao M. B. , Li Yuncong 
Published: July 2023

AbstractDespite evidence suggesting that biochar can retain nutrients, particularly nitrogen (N), and reduce the risks of transport, research on the co‐application of biochar with organic and inorganic fertilizer sources is limited. Three laboratory studies (herein referred to as static incubation, column leaching, and batch sorption) were conducted to evaluate the impacts of two biochar materials (pine and grass biochar generated at temperatures of 800 and 400°C, respectively) on N and carbon (C) dynamics in soils amended with different N sources (ammonium nitrate, Class B, and Class AA biosolids). Nitrogen sources were applied at an equivalent rate of 180 kg N ha−1 while biochar was applied at a 1% (w/w) rate. Biochar effects on soil N and C dynamics were variable and dependent on biochar and N sources. A negligible but significant effect of pine biochar in reducing NH4 leaching was observed; however, both biochar materials were ineffective in reducing NO3 or inorganic N leaching. Reductions in leachate NH4 by pine biochar were attributed to relative greater ability of this material to retain NH4 than grass biochar. Both biochar materials exhibited no ability to sorb NO3. Similarly, biochar had no effect on soil N2O emissions. Class B biosolids resulted in greater N leaching and soil N2O emissions compared to other fertilizers. This response was likely due to inherently high levels of inorganic N and moisture, which possibly favored denitrification. Further research is warranted to better understand the underlying mechanisms controlling soil N and C dynamics and responses to co‐application with fertilizer sources.
Heterotypic communication as the promoter of phenotypic plasticity of cancer cells: The role of cancer secretomes
Authors: Zelanis André , Barcick Uilla , Racorti Nathália de Vasconcellos , Salardani Murilo 
Published: July 2023

AbstractCellular communication relies on signaling circuits whose statuses are mainly modulated by soluble biomolecules such as carbohydrates, lipids, proteins, and metabolites as well as extracellular vesicles (EVs). Therefore, the active secretion of such biomolecules is critical for both cell homeostasis and proper pathophysiological responses in a timely fashion. In this context, proteins are among the main modulators of such biological responses. Hence, profiling cell line secretomes may be an opportunity for the identification of “signatures” of specific cell types (i.e., stromal or metastatic cells) with important prognostic/therapeutic value. This review will focus on the biological implications of cell secretomes in the context of cancer, as well as their functional roles in shaping the tumoral microenvironment (TME) and communication status of participating cells.
Comparison of uncertainty quantification methods for cloud simulation
Authors: Janjić T. , Lukáčová‐Medviďová M. , Ruckstuhl Y. , Wiebe B. 
Published: July 2023

AbstractQuantification of evolving uncertainties is required for both probabilistic forecasting and data assimilation in weather prediction. In current practice, the ensemble of model simulations is often used as a primary tool to describe the required uncertainties. In this work, we explore an alternative approach, the so‐called stochastic Galerkin (SG) method, which integrates uncertainties forward in time using a spectral approximation in stochastic space. In an idealized two‐dimensional model that couples nonhydrostatic weakly compressible Navier–Stokes equations to cloud variables, we first investigate the propagation of initial uncertainty. Propagation of initial perturbations is followed through time for all model variables during two types of forecast: the ensemble forecast and the SG forecast. Series of experiments indicate that differences in performance of the two methods depend on the system state and truncations used. For example, in more stable conditions, the SG method outperforms the ensemble of simulations for every truncation and every variable. However, in unstable conditions, the ensemble of simulations would need more than 100 members (depending on the model variable) and the SG method more than a truncation at five to produce comparable but not identical results. As estimates of the uncertainty are crucial for data assimilation, secondly we instigate the use of these two methods with the stochastic ensemble Kalman filter. The use of the SG method avoids evolution of a large ensemble, which is usually the most expensive component of the data assimilation system, and provides results comparable with the ensemble Kalman filter in the cases investigated.
Commonly Neglected Ester Groups Enhanced Microwave Absorption
Authors: Jin Haoshan , Zhou Jintang , Tao Jiaqi , Gu Yansong , Yu Chunyi , Chen Ping , Yao Zhengjun 
Published: July 2023

AbstractOxygen‐containing functional groups have high potential to excite polarization loss. The nature and mechanism of the polarization loss brought on by oxygen‐containing functional groups, however, remain unclear. In this study, metal‐organic framework precursors are in situ pyrolyzed to produce ultrathin carbon nanosheets (UCS) that are abundant in oxygen functional groups. By altering the pyrolysis temperature, the type and concentration of functional groups are altered to produce good microwave absorption capabilities. It is demonstrated that the main processes of electromagnetic loss are polarization caused by “field effects and induced effects” brought on by strongly polar ester functional groups. Moreover, links between various oxygen functional groups and structural flaws are established, and their respective contributions to polarization are sharply separated. The sample with the highest ester group content ultimately achieves an effective absorption bandwidth of 6.47 GHz at a pyrolysis temperature of 800°C. This research fills a theoretical hole in the frequently overlooked polarization mechanism in the microwave band by defining the key polarization parameters in chaotic multiple dipole systems and, in particular, redefining the significance of ester groups.
Building a Bridge: Writing and Reading Connections in Early Childhood
Authors: Quinn Margaret F. , Traga Philippakos Zoi A. 
Published: July 2023

AbstractReading and writing are essential components of literacy. Children's initial preschool experiences with literacy set important foundations for later school success. Instruction that can create a bridge between reading and writing to support children's developing understandings in both these areas of literacy has powerful implications for their literacy growth. This teaching and learning in action guide explores meaningful connections between reading and writing by examining the way in which one prekindergarten teacher supports children's reading–writing skills across various components of written language (i.e., sounds, letters, words, sentences, and content) and within various instructional contexts (centers, small groups, large group/read‐aloud). This article shares research‐based approaches in the context of specific examples in which the focal teacher fosters meaningful reading and writing connections using two key read‐alouds as starting points. How do we make reading–writing connections in preschool across contexts and learning experiences to support children's literacy in meaningful, engaging, and developmentally appropriate ways and make connections visible to children? What high‐quality reading and writing experiences influence preschoolers' engagement in activities? What ways are reading and writing addressed in your classroom across various instructional contexts (i.e., whole group, small group, centers)?
Impact of biochar amendments on soil water and plant uptake dynamics under different cropping systems
Authors: Thao Touyee , Arora Bhavna , Ghezzehei Teamrat A. 
Published: July 2023

AbstractApplication of biochar amendments in agricultural systems has received much attention in recent years. In this study, we assess the 5‐year impacts of biochar application on soil water and plant interactions for an irrigated fresh market tomato (Solanum lycopersicum) and a rainfed pasture (Poaceae) cropping system. In particular, we focus on three varieties of locally produced biochar from agricultural waste materials—almond shell, walnut shell, and almond pruning residues that are pyrolyzed using a mobile pyrolysis unit. We used the soil hydrological model HYDRUS‐1D to explicitly track seasonal and annual soil water fluxes through changes in water retention, drainage, evaporation, and plant water uptake under biochar application. Modeling results show that the application of biochar at 5% increased soil water availability within the top 20 cm for a rainfed system, irrespective of biochar amendment type. This is clearly indicative of higher plant water uptake and greater water use efficiency (WUE) under biochar application. In contrast, a similar biochar amendment for the irrigated system did not affect WUE, instead reducing seasonal soil evaporation loss and thereby reducing irrigation demand. In both cropping systems, year‐to‐year variability in precipitation significantly impacted the total amount of water saved under biochar application with certain amendments retaining more water than others. Given that biochar application increased water retention irrespective of cropping systems, we further used a simple approach to determine yield trade‐off, if any, between control and biochar treatments. Our economic balance clearly demonstrates that the water saved by amending soil with biochar does not offset the yield disparity if compensated with carbon credits and therefore, application of biochar should be actively considered for both its direct and indirect benefits to potential greenhouse gas mitigation (e.g., diverting orchard waste from open burning), water savings, and soil health.