bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efficacy of Vitrectomy with Air Tamponade for Rhegmatogenous Retinal Detachment: A Prospective Study
Authors: Nishi Katsuhiro , Nakamura Madoka , Nishitsuka Koichi 
Published: April 2023

Abstract
Rhegmatogenous retinal detachment (RRD) causes a permanent decrease in visual acuity and visual field. During pars plana vitrectomy (PPV) for RRD, long acting gas have been selected for tamponade because gas stays in the eye for a long time. Recently, several studies have showed the efficacy of air tamponade for RRD treatment. Few prospective studies have analyzed the efficacy of air tamponade. We registered 194 eyes from 190 patients who consented to a prospective study of PPV with air tamponade for RRD by a single surgeon from June 2019 to November 2022. These patients were all treated with air tamponade without silicone oil and were followed for > 3 months postoperatively. Primary success rates were 97.9% (190/194) in total cases, with no discernible difference between the uncomplicated (100%:87/87) and complicated (96.3%: 103/107) RRD groups (P = 0.13). There was no considerable difference in primary success rate between upper break (97.9%:143/146) and lower break cases (97.9%:47/48). Proliferative vitreoretinopathy (PVR) grade C was associated with initial failure by multivariate analysis (P = 0.00003). Air tamponade has a sufficient therapeutic effect in cases of RRD less than PVR grade C, regardless of the location of the retinal tear.
The value of EYA1/3/4 in Clear Cell Renal Cell Carcinoma: a study from multiple databases
Authors: Liu Taobin , Nie Jianqiang , Zhang Xiaoming , Deng Xinxi , Fu Bin 
Published: April 2023

Abstract
Background: There is evidence from multiple studies that dysregulation of the Eyes Absent (EYA) protein plays multiple roles in many cancers. Despite this, little is known about the prognostic significance of the EYAs family in clear cell renal cell carcinoma (ccRCC).
Methods: We systematically analyzed the value of EYAs in Clear Cell Renal Cell Carcinoma. Our analysis included examining transcriptional levels, mutations, methylated modifications, co-expression, protein-protein interactions (PPIs), immune infiltration, single-cell sequencing, drug sensitivity, and prognostic values. We based our analysis on data from several databases, including the Cancer Genome Atlas database (TCGA), the Gene Expression Omnibus database (GEO), UALCAN, TIMER, Gene Expression Profiling Interactive Analysis (GEPIA), STRING, cBioPortal and GSCALite.
Results: In patients with ccRCC, the EYA1 gene was significantly highly expressed, while the expression of EYA2/3/4 genes showed the opposite trend. The level of expression of the EYA1/3/4 gene was significantly correlated with the prognosis and clinicopathological parameters of ccRCC patients. Univariate and multifactorial Cox regression analyses revealed EYA1/3 as an independent prognostic factor for ccRCC, establishing nomogram line plots with good predictive power. Meanwhile, the number of mutations in EYAs was also significantly correlated with poor overall survival (OS) and progression-free survival (PFS) of patients with ccRCC. Mechanistically, EYAs genes play an essential role in a wide range of biological processes such as DNA metabolism and double-strand break repair in ccRCC. The majority of EYAs members were related to the infiltration of immune cells, drug sensitivity, and methylation levels. Furthermore, our experiment confirmed that EYA1 gene expression was upregulated, and EYA2/3/4 showed low expression in ccRCC.
Conclusion: The increased expression of EYA1 might play an important role in ccRCC oncogenesis, and the decreased expression of EYA3/4 could function as a tumor suppressor, suggesting EYA1/3/4 might serve as valuable prognostic markers and potential new therapeutic targets for ccRCC.
Method of hydraulic control detection and fault diagnosis of construction machinery based on machine learning
Authors: Ma Jianqiang 
Published: April 2023

Abstract
With the continuous development of the times, the hydraulic system of construction machinery has become one of the important components of the hydraulic system and has been widely used in the construction machinery industry. If the hydraulic pressure of the construction machinery detects a fault, the entire production line will stop working, resulting in heavy losses to the enterprise. The hydraulic system of construction machinery is expensive in terms of its own cost and maintenance cost. Therefore, the control detection and fault diagnosis of hydraulic system of construction machinery has the highest value in engineering applications. In this paper, the neural network model used is based on the classification characteristics of neural network in machine learning. Through extracting and standardizing the sample data processing function, the hydraulic control detection and fault diagnosis of construction machinery have been successfully realized. For the defects of parameter selection in machine learning, such as the difficulty of selecting parameter attributes, and the difficulty of falling into local optimization in the face of complex structure, the diagnosis method based on multi-layer hidden MLP model is adopted. This method can directly extract the feature quantity and input it into the MLP model for proper training, so as to make the learning network more in-depth, so as to ensure the reliability of production and improve the accuracy of model fault diagnosis, and use the neural network diagnosis method to process multi-dimensional data in machine learning.
Broadband High-Efficiency 3-bit Coding Metasurfacein Tramsmission Mode Based on the Polarization Conversion Technique
Authors: Karimipour Majid , Heydari Mohammad Bagher , Aryanian Iman 
Published: April 2023

Abstract
The main drawback of the transmissive focusing metasurface (TFM) is its low operational bandwidth and low aperture efficiencywhich usually the simultaneous increase of these two radiation characteristics is a major challenge in these structures. Thispaper introduces a novel multi-state coding metasurface with an enhanced frequency bandwidth and efficiency exploitingsystem-level and element-level synthesis approaches. Unlike most of the TFMs proposed in this concern, the proposed novelelement consists of only two dielectric layers. The system-level synthesis approach is implemented by the well-establishedbroadband technique named multi-frequency phase synthesis (MFPS) using an optimization algorithm to balance the phaseerror in the whole band in terms of gain and aperture efficiency. At the element design level, a wideband technology based onthe polarization conversion technique (PCT) is adopted and implemented by a subwavelength non-resonant element which iscomposed of three C-shape metallic patterns. The metal layers are printed on two sides of two identical dielectric layers withoutusing any metalized via in the configuration. Eight states of phase quantization are realized by simply changing the angle of arccurves in all layers. The amplitude of the transmitted wave with rotated polarization is larger than 0.9 from 12.3 GHz to 16.5GHz. A 25×25-element TFM is designed, fabricated, and tested by the above broadband technique. The measurement resultsdemonstrate that the 1-dB gain bandwidth of the antenna is 12.3-16.5 GHz which is equal to 29%. The maximum measuredaperture efficiency is 53.6%, which occurs at 12.8 GHz. The proposed metasurface is classified in the group of broadbandhigh-efficiency TFM.
SST interneurons modulate neocortical network through GABAb receptors in a synapse- specific manner
Authors: Kanigowski Dominik , Bogaj Karolina , Barth Alison L. , Urban-Ciecko Joanna 
Published: April 2023

Abstract
The firing activity of somatostatin-expressing inhibitory neurons (SST-INs) can suppress network activity via both GABAa and GABAb receptors (Rs). Although SST-INs do not receive GABAaR input from other SST-INs, it is possible that SST-IN-released GABA could suppress the activity of SST-INs themselves via GABAbRs, providing a negative feedback loop. Here we characterized the influence of GABAbR modulation on SST-IN activity in layer 2/3 of the somatosensory cortex in mice. We compared this to the effects of GABAbR activation on parvalbumin-expressing interneurons (PV-INs). Using in vitrowhole-cell patch clamp recordings, pharmacological and optogenetic manipulations, we found that the firing activity of SST-INs suppresses excitatory drive to themselves via presynaptic GABAbRs. Postsynaptic GABAbRs did not influence SST-IN spontaneous activity or intrinsic excitability. Although GABAbRs at pre- and postsynaptic inputs to PV-INs are modestly activated during cortical network activity in vitro, the spontaneous firing of SST-INs was not the source of GABA driving this GABAbR activation. Thus, SST-IN firing regulates excitatory synaptic strength through presynaptic GABAbRs at connections between pyramidal neurons (Pyr-Pyr) and synapses between pyramidal neurons and SST-INs (Pyr-SST), but not Pyr-PV and PV-Pyr synapses. Our study indicates that two main types of neocortical inhibitory interneurons are differentially modulated by SST-IN-mediated GABA release.
Plicae palmatae on MR in uterus didelphys: the incidence and morphological characteristics
Authors: Sun Zhaonan , He Jiangkai , Huang Wenpeng , Wang Xiaoying 
Published: April 2023

Abstract
Objective: To investigate the incidence of plicae palmatae in uterus didelphys and its morphological characteristics on MR imaging.
Methods: We retrospectively collected 37 consecutive female pelvic MR images diagnosed with uterus didelphys between August 2012 and November 2020. Patients with the following conditions were excluded: (a) repeated examination; (b) poor image quality; (c) cervical disease. Axial and coronal T2-weight images and axial three-dimensional (3D) volumetric isotropic T2-weighted acquisition (VISTA) were used to evaluate the ridge of plicae palmatae (RPP). A multiplanar reformation of the cervical axis from 3D-VISTA sequence was performed to measure the height and width of RPP. Non-normal variables based on the Kruskal-Wallis H test was used for statistical analysis. A two-tailed test where P < 0.05 was considered statistically significant.
Results: Twenty-six cases were finally included in the statistics. The average age was 25.7±9.0 years (range, 10-45 years). RPP was observed on both cervices in 16 patients (61.5%), only on the left cervix in 3 patients (11.5%), and only on the right cervix in 4 patients (15.4%). There were 3 cases with no RPP observed in any of their cervix (11.5%). All RPP appear symmetrically on the anterior and posterior walls of the cervix. There was no statistically significant difference in height, width, and height/width of the RPP in the left and right cervix (p＞0.05).
Conclusions: RPP is encountered in 88.5% patients with duplicated uterine cervices in our cohort. This incidence is similar to that reported in women with normal uterus of reproductive age.
Isolation, characterization and genomic analysis of a novel Arthrobacter sp. phage SWEP2
Authors: Han Miao , Niu Xinyao , Xiong Guangzhou , Ruan Chujin , Chen Guowei , Wu Hanqing , Liu Ying , Zhu Kun , Wang Gang 
Published: April 2023

Abstract
In this study, a virulent phage, designated SWEP2, which infects Arthrobacter sp. 5B strain was isolated from the black soil in Northeast China. The phage SWEP2 has a latent period of 80 min and the burst size of 45 PFU (test on MOI=0.1). Through genomic analyses, this 43,412 bp dsDNA phage SWEP2 was found to consist of 66 open reading frames (ORFs) and 1 tRNA gene. The SWEP2 is closely related to Arthrobacterphage Liebe (82.98% identity, 49% query coverage). Based on its phenotypic and genotypic characterization, the SWEP2 is a novel Arthrobacter phage.
Attentional, emotional, and behavioral response toward spiders, scorpions, crabs, and snakes: Do they all scare us?
Authors: Landová Eva , Štolhoferová Iveta , Vobrubová Barbora , Polák Jakub , Sedláčková Kristýna , Janovcová Markéta , Rádlová Silvie , Frynta Daniel 
Published: April 2023

Abstract
Spiders evoke significant fear and disgust in many people; such a complex response has been formed throughout human evolution. However, most spiders do not present a serious threat, so the evolutionary explanation is controversial. We suggest that other chelicerates, e.g., scorpions, might have been important in the formation and fixation of the spider-like category. In this eye-tracking study, we checked for some aspects of the attentional, behavioral, and emotional response to the spider, scorpion, snake, and crab stimuli used as task-irrelevant distractors. Results showed that spider-fearful participants were selectively distracted by spiders, but also by crabs which were not consciously rated as fear-eliciting. We hypothesize that spider-fearful participants might have mistaken crabs for spiders based on their shared physical characteristics. Contrary, participants with no fear of spiders were distracted the most by snakes and scorpions. No difference between snake and scorpion distractors was found supporting the notion that scorpions are also prioritized, evolutionary relevant stimuli. We conclude that scorpions are evolutionary fear-relevant stimuli, however, the generalization between scorpions and spiders was not supported in spider-fearful participants. This result might be important for a better understanding of the evolution of spider phobia.
Comparison of the applicability of seven calculation equations of glomerular filtration rate among elderly people in China
Authors: Zhu Weiwei , Zhang Yingyu , Chen Shutao , Sui Yang , Wang Xufang , Li Wei , Juan Chenxia , Zhou Yan , Gao Kun 
Published: April 2023

Abstract

Background
The evaluation of kidney injury severity is a crucial aspect of medical practice. At present, glomerular filtration rate (GFR) serves as the primary indicator for this assessment. Estimated GFR (eGFR) remains the most frequently utilized parameter in clinical settings. Numerous equations have been formulated based on serum creatinine (Scr) or serum cystatin C (Cysc) levels. However, there is a lack of consensus regarding the efficacy of these equations in assessing eGFR, particularly for elderly individuals in China. This study aimed to evaluate the applicability of the MDRD, MDRDc, CKD-EPI series, BIS1, and FAS equations within the Chinese elderly population.
Methods
A cohort of 298 elderly patients with measured GFR (mGFR) determined by the dual plasma sample clearance method using 99m-Technetium-diethylenetriamine-pentaacetic acid (99m Tc-DTPA) renal dynamic imaging was enrolled. The patients were categorized into three subgroups based on their mGFR levels. The eGFR performance was examined, taking into account bias, interquartile range (IQR), accuracy P30, and root-mean-square error (RMSE). Bland-Altman plots were employed to verify the validity of eGFR.
Results
The 298 participants had a median age of 71 years, with 167 (56.0%) being male. In reference to mGFR (48.77 ml/min/1.73 m2), the CKD-EPI-Scr, CKD-EPI-Cysc, CKD-EPI-Scr-Cysc, MDRD, MDRDc, FAS, and BIS1 equations estimated GFR at 50.38, 49.08, 45.28, 51.65, 54.00, 38.73, and 48.80 ml/min/1.73 m2, respectively. Overall, no significant differences in bias were observed among the seven equations (P > 0.05). In terms of IQR, P30, and RMSE, the BIS1 equation demonstrated superior accuracy compared to the other equations (14.61, 72.1%, and 13.53, respectively). When mGFR < 30ml/min/1.73m2, all equations underestimated the true GFR, with the highest accuracy reaching only 59%. Bland-Altman plots indicated that the BIS1 equation exhibited the highest accuracy, featuring a 95% confidence interval (CI) width of 52.37 when compared to the other equations.
Conclusions
This study suggested that the BIS1 equation stands out as the most applicable for estimating GFR in Chinese elderly patients with normal renal function or only moderate decline.
Environmental and economic determinants of temporal dynamics of the ruminant movement network of Senegal
Authors: Garcia Katherin Michelle Garcia , Apolloni Andrea , Giacomini Alessandra , Ciss Mamadou , Fall Mathioro , Gaye Adji Maréme , Arsevska Elena , Mesdour Asma , Chevanne Etienne , Rosso Fabrizio , Cardinale Eric , Diaw Cécile Squarzoni , Seck Ismaila , Lo Mbargou , Delabouglise Alexis 
Published: April 2023

Abstract
Our understanding of the divers of the temporal dynamics of livestock mobility networks is currently limited, despite their significant implications for the surveillance and control of infectious diseases. We analyzed the effect of time-varying environmental and economic variables - biomass production, rainfall, livestock market prices and religious calendar - on long distance movements of cattle and small ruminant herds in Senegal in years 2014 and 2019. We used principal component analysis to explore the variation of the hypothesized explanatory variables in space and time and a generalized additive modelling approach to assess the effect of those variables on the likelihood of herd movement between pairs of administrative units. Contrary to environmental variables, the patterns of variation of market prices show significant differences across locations. The explanatory variables at origin had the highest contribution to the model deviance reduction. Biomass production and rainfall were found to affect the likelihood of herd movement for both species on at least one year. Market price at origin had a strong and consistent effect on the departure of small ruminant herds. Our study shows the potential benefits of a regular monitoring of market prices for future efforts at forecasting livestock movements and associated sanitary risks.
A Study on Perioperative Complications of Splenectomy in Emergency &amp; Elective Cases: a Short Term
Authors: NARZARY HIRANMOY NARZARY Dr HIRANMOY , SARKAR AMITABHA SARKAR DR AMITABHA 
Published: April 2023

Abstract
Splenectomy being one commonly performed surgeries throughout the world is well known to have many complications. Heterogeneity exists in presentation, some being hematological or chest infections. Due to advancement of medical science, complications have reduced. Yet still some exist despite precautions and vaguely recorded in literature. We aim to study the incidence of complications of splenectomy in elective & emergency settings during perioperative period to demonstrate the present status and discuss the future changes in preventing or treating complications.
Complex Endoleak Treatment After Failed Endovascular Aortic Repair
Authors: Raupach Jan , Masek Jan , Venugopal Sindharta , Renc Ondrej , Lesko Michal , Maly Radovan 
Published: April 2023

Abstract
Background
Endovascular aneurysm repair (EVAR) has created new possibilities for patients with abdominal aortic aneurysms (AAAs), and in recent years it has become tremendously popular. Use of EVAR in selected groups of patients allows mortality and morbidity to be reduced in comparison to open repair. However, complications such as endoleaks (ELs) can be of great concern and warrant urgent therapy to prevent sac rupture.
Case Presentation
The case report presents urgent endovascular treatment of a high-risk type IA EL in a polymorbid 68-year-old patient 7 years after primary EVAR. The principle of treatment was parallel implantation of the proximal SG extension with the renal SG into the right renal artery (chimney technique). The subsequent type II collateral EL was treated by direct transabdominal AAA sac puncture and thrombin embolization.
Conclusion
EL can be a cause for urgent intervention, but specific anatomic features often require specialized SG types which are not readily available. The chimney technique allows the use of immediately available stent grafts to address endoleak in the setting of impending abdominal aneurysm rupture.
Deformation error compensation by stiffness model of mechanical joint on a flexible track drilling robot for aircraft assembly
Authors: Li Zhihao , Tian Wei , Hu Junshan , Wang Min , Li Bo , Liao Wenhe 
Published: April 2023

Abstract
The level of automation and precision in aircraft assembly determines the effectiveness and quality of aircraft manufacturing. In contrast, the unstable localization accuracy resulting from the layout pattern of flexible track drilling robot has limited their further development and applications in domains with high machining accuracy requirements, such as aircraft assembly. This study begins by presenting the paradox between the need for high-precision drilling tasks during aircraft construction and the lack of accuracy of automated drilling equipment. The problem of self-precision loss due to flexible track drilling devices is examined in a new application scenario where the overall position and pose layout change with the location of the process station. Then, the characteristics of the weak rigidity of the transmission system of the flexible track drilling robot at the joint surface and the variation of the transmission axial load due to variations in the position and pose of the drilling process station are examined. In addition, an equivalent stiffness model is developed to predict the incremental error of the entire process station, and the incremental error conjecture due to the elastic deformation of the coupling surface of the transmission system is proposed as an optimization algorithm for global position accuracy compensation. Finally, the incremental error conjecture is discussed and validated by designing ablation test groups one by one and evaluating the effect of the precision compensation algorithm. Experimental results showed that the incremental error compensation method optimized 68.67 percent of the total error.
Silencing of the Vasa gene by RNA interference affects embryonic development and reproductive output in the sea louse Caligus rogercresseyi
Authors: Bustos Paulina , Schmitt Paulina , Brown Donald I. , Farlora Rodolfo 
Published: April 2023

Abstract
The sea louse Caligus rogercresseyi is a major ectoparasitic copepod that causes significant economic losses in the salmon farming industry. Despite recent advancements, the mechanisms underlying germline and embryo development in this species remain poorly understood. The Vasa gene encodes a highly conserved DEAD-box helicase, that is required for germ cell formation and function in many species. In this study, the Vasa gene was characterized in C. rogercresseyi, and its expression and function were analyzed. Phylogenetic analysis showed that the Cr-Vasa gene product formed clusters in clades with Vasa proteins from closely related species of crustaceans. Cr-Vasa gene expression patterns were assessed by qPCR, and results showed a significantly higher relative expression level in adult females compared to copepodid, chalimus, and adult male stages. Tissue-specific localization of Cr-Vasa mRNA in C. rogercresseyi was determined using chromogenic in situ hybridization, and strong positive signal was observed in male testes, but also in the intestine and cuticle, while in females, it was observed in the ovaries, oocytes, cuticle, intestine, and egg strings. RNAi-mediated gene silencing of Cr-Vasa impacted embryonic development and reproductive output in adult female lice. Females from the dsVasa-treated group displayed unusual phenotypes, including shorter egg strings with numerous extra-embryonic inclusions, irregularly shaped abnormal embryos, and aborted egg strings. This study provides insights into the role of the Vasa gene in C. rogercresseyi embryonic development and reproductive output, which may have implications for the control of this parasitic copepod in the salmon farming industry.