bluuebunny/crossref_metadata_2025_split huggingface dataset:
Knowledge is (Reproductive) Power
Authors: Marks Claire , Prasad Priyanka K. , Stout Julianne 
Published: February 2023

Background:
Recent data suggests female physicians can be up to twice as likely to experience infertility compared to the general population. Despite this, fertility and family planning are rarely incorporated into formal medical education. In this study, medical students’ knowledge and perspectives regarding childbearing were investigated along with how fertility-related information could be presented in medical curricula.

Materials and Methods:
An anonymous, online questionnaire was designed for this study, comprised of multiple choice, open ended, and Likert questions. Respondents were recruited from medical students in all phases of training at a large, Midwest medical school, yielding 184 responses. The survey included sections on knowledge, perspectives, curriculum, and demographics.

Results:
The average score on fertility knowledge was 70%. Most respondents were interested in having biological children (76% agreed/strongly agreed). Students worried about having children during medical education (71% agreed/strongly agreed). About 40% of respondents disagreed/strongly disagreed that their institution would support their decisions regarding family building. Respondents indicated benefits of delayed childbearing are financial stability, career establishment, and increased maturity. Nearly 80% of individuals preferred that fertility education be a required component of the medical curriculum.

Conclusions:
These results suggest many medical students hope to have children and are aware of the logistical challenges associated with childbearing during medical training. However, they may not fully appreciate the impact of biological decline in fertility over time, potentially a factor contributing to increased physician infertility. Further curricular content addressing fertility would be beneficial to undergraduate medical students.
Utility of Three-Dimensional Virtual and Printed Models for Veterinary Student Education in Congenital Heart Disease
Authors: Markovic Lauren E. , Nguyen Sarah , Clouser Sherry 
Published: February 2023

Introduction:
Congenital heart disease (CHD) is a common heart defect that can be present in small and large animals at birth. Student understanding of normal and abnormal cardiac anatomy is imperative for proper diagnosis and management of CHD. Objectives were to create and use three-dimensional (3D) heart models during a workshop to understand veterinary student perception of 3D models for CHD education. We hypothesized that 3D models would enhance student understanding of CHD, and students would prefer 3D models during cardiac education.

Materials and Methods:
Computed tomography angiography datasets from canine patent ductus arteriosus were used to create 3D models. Segmentation and computer-aided design were performed. Virtual overlays of 3D models were displayed onto two-dimensional (2D) thoracic radiographs. Stereolithography files were fabricated by a 3D printer. Students participated in a CHD workshop consisting of 2D and 3D teaching stations. Self-assessment surveys before and after the workshop were completed.

Results:
Twenty-two veterinary students attended the workshop. The 3D-printed models were found to be the most helpful teaching modality based on students’ perception. The 3D-printed model (P < 0.0001) and the 3D digital model (P < 0.0001) were perceived to be significantly more helpful than the 2D radiograph station. All students strongly agreed (15/22) or agreed (7/22) that virtual models overlayed onto 2D radiographs enhanced their spatial recognition of anatomic structures. All students strongly agreed (17/22) and agreed (5/22) that the CHD workshop was a valuable learning opportunity.

Conclusion:
Creation of virtual and fabricated 3D heart models is feasible. Three-dimensional models may be helpful when understanding spatial recognition of cardiovascular anatomy on thoracic radiographs. We advocate using 3D heart models during CHD education.
Treatment satisfaction and medication adherence among hypertensive patients in a teaching hospital in Ekiti State, Nigeria
Authors: AKPOR Oluwaseyi Abiodun , OLOWOLAJU Florence Olutola 
Published: February 2023

Objective:
This study investigates treatment satisfaction and medication adherence among hypertensive patients attending the medical outpatient clinic of a teaching hospital in Ekiti State, Nigeria.

Materials and Methods:
The study design was descriptive and cross-sectional using quantitative research strategy. A systematic sampling technique was used in selecting 270 participants; a structured questionnaire was used for data collection. Medication adherence was assessed using the 8-item Morisky Medication Adherence Scale, and treatment satisfaction was assessed using the 14-item Treatment Satisfaction Questionnaire for Medication.

Results:
The study findings revealed that majority (73.7%) of the study participants had good knowledge of hypertension, while 44.4% had a good level of treatment satisfaction. Test of association of participants' sociodemographic characteristics revealed age (χ
2 = 23.773, P = 0.003) and occupation (χ
2 = 21.251, P = 0.019) to be significantly associated with treatment satisfaction. The level of medication adherence by the participants was observed to be relatively poor (50.4%). The educational status (χ
2 = 23.914, P = 0.001) and monthly income (χ
2 = 10.406, P = 0.034) of the participants showed significant association with medication adherence.

Conclusion:
The study recommends that improving patients' understanding of their disease and treatment with subsidizing hypertensive medications by the government will enhance medication adherence.
Quality of life and psychological impact among chronic disease patients during the COVID-19 pandemic
Authors: AL MAQBALI Mohammed , ALSAYED Ahmad , BASHAYREH Ibrahim 
Published: February 2023

Objective:
Patients diagnosed with chronic disease may experience psychological symptoms including depression, anxiety, insomnia, and fatigue, all of which may adversely affect their quality of life (QoL). The main objective of this study is to identify the level of QoL, to know the prevalence of these symptoms among chronic disease patients in Oman during the third wave of coronavirus disease 2019 (COVID-19) pandemic, and to explore the contributing factors.

Methods:
A cross-sectional and descriptive correlational design was used. Convenience sampling was used to recruit participants. Data were collected using the Functional Assessment of Chronic Therapy (FACT)–General, Hospital Anxiety and Depression Scale, the Insomnia Severity Index, and the FACT–Fatigue subscale via Qualtrics® software. Linear regression analyses were used to explore factors that were associated with QoL.

Results:
Of 990 patients with chronic disease who participated, the mean total QoL score was 67.7 (standard deviation = 16.1). Participants aged above 51, those with a basic education, those with heart disease, or those with more than one comorbidity had a significantly lower QoL. Linear regression revealed that the main factors associated with lower QoL included heart disease (β = 0.05, P = 0.02), diabetes (β = 0.12, P < 0.01), having taken one dose of COVID-19 vaccine (β = 0.05, P = 0.04), anxiety (β = −0.24, P < 0.01), depression (β = −0.31, P < 0.01), insomnia (β = −0.12, P < 0.01), and fatigue (β = 0.27, P < 0.01).

Conclusions:
The COVID-19 pandemic has significantly reduced the individuals' level of QoL and affected the mental health of patients diagnosed with chronic diseases. Appropriate strategies to monitor psychological problems and interventions to prevent and reduce these among such patients are needed.
What We Lost in the Fire: Endemic Tropical Heart Diseases in the Time of COVID-19
Authors: Chang Andrew Y. , Zühlke Liesl , Ribeiro Antonio Luiz P. , Barry Michele , Okello Emmy , Longenecker Chris T. 
Published: February 2023

ABSTRACT.
The COVID-19 pandemic has profoundly influenced the effort to achieve global health equity. This has been particularly the case for HIV/AIDS, tuberculosis, and malaria control initiatives in low- and middle-income countries, with significant outcome setbacks seen for the first time in decades. Lost in the calls for compensatory funding increases for such programs, however, is the plight of endemic tropical heart diseases, a group of disorders that includes rheumatic heart disease, Chagas disease, and endomyocardial fibrosis. Such endemic illnesses affect millions of people around the globe and remain a source of substantial mortality, morbidity, and health disparity. Unfortunately, these conditions were already neglected before the pandemic, and thus those living with them have disproportionately suffered during the time of COVID-19. In this perspective, we briefly define endemic tropical heart diseases, summarizing their prepandemic epidemiology, funding, and control statuses. We then describe the ways in which people living with these disorders, along with the healthcare providers and researchers working to improve their outcomes, have been harmed by the ongoing COVID-19 pandemic. We conclude by proposing the path forward, including approaches we may use to leverage lessons learned from the pandemic to strengthen care systems for these neglected diseases.
In Vitro and In Vivo Validation of CYP6A14 and CYP6N6 Participation in Deltamethrin Metabolic Resistance in Aedes albopictus
Authors: Peng Hui , Wang Haiyang , Guo Xiuxia , Lv Wenxiang , Liu Lijuan , Wang Haifang , Cheng Peng , Liu Hongmei , Gong Maoqing 
Published: February 2023

ABSTRACT.
The extensive use of chemical insecticides for public health and agricultural purposes has increased the occurrence and development of insecticide resistance. This study used transcriptome sequencing to screen 10 upregulated metabolic detoxification enzyme genes from Aedes albopictus resistant strains. Of these, CYP6A14 and CYP6N6 were found to be substantially overexpressed in the deltamethrin-induced expression test, indicating their role in deltamethrin resistance in Ae. albopictus. Furthermore, the corresponding 60-kDa recombinant proteins, CYP6A14 and CYP6N6, were successfully expressed using the Escherichia coli expression system. Enzyme activity studies revealed that CYP6A14 (5.84 U/L) and CYP6N6 (6.3 U/L) have cytochrome P450 (CYP450) enzyme activity. In vitro, the metabolic analysis revealed that the recombinant proteins degraded deltamethrin into 1-oleoyl-sn-glycero-3-phosphoethanolamine and 2′,2′-dibromo-2′-deoxyguanosine. Subsequently, the CYP450 genes in larvae of Ae. albopictus were silenced by RNA interference technology to study deltamethrin resistance in vivo. The silencing of CYP6A14 and CYP6N6 increased the mortality rate of mosquitoes without affecting their survival time, spawning quantity, hatching rate, and other normal life activities. Altogether, CYP6A14 and CYP6N6 belong to the CYP6 family and mutually increase deltamethrin resistance in Ae. albopictus.
A Rapid Point-of-Care Assay for Cysticercosis Antigen Detection in Urine Samples
Authors: Toribio Luz , Handali Sukwan , Marin Yazmin , Perez Erika , Castillo Yesenia , Bustos Javier A. , O’Neal Seth E. , Garcia Hector H. 
Published: February 2023

ABSTRACT.
We report a proof-of-concept study using a dipstick assay to detect Taenia solium antigen in urine samples of 30 patients with subarachnoid neurocysticercosis and 10 healthy control subjects. Strips were read in blind by two readers. The assay detected antigen in 29 of 30 cases and was negative in all 10 control samples. Although this study was performed in samples from individuals with subarachnoid neurocysticercosis who likely had high circulating antigen levels, it provides the proof of concept for a functional urine antigen point-of-care assay that detects viable cysts. Such an assay could serve to support a clinical diagnosis of suspect neurocysticercosis or to identify patients at risk of developing severe disease in areas where medical resources are limited, providing evidence to refer these individuals for imaging and specialized care as needed.
DRIVERS OF ECONOMIC PERFORMANCE: DO INSTITUTIONAL QUALITY AND FINANCIAL LIBERALIZATION MATTER? EVIDENCE FROM SANE AND ASIAN TIGERS
Authors: Nzeh, Innocent Chile  , Ogwuru, Hycenth Oguejiofoalu Richard  , Izuogu, Augustine Chinedu  , Ogaraku, Nneoma Bridget  
Published: February 2023

The aim of this study is to examine the impact of financial liberalization and institutional quality on the economic performance of the Asian Tigers and the SANE countries. The study used annual series that spanned the period from 1996-2020 under the framework of FMOLS. Findings of the study revealed that in the Asian Tigers, FDI inflows, FDI outflows, capital account openness and governance effectiveness had a positive and significant impact on the GDP per capita, but the impact of political stability was negative and significant. Results for the SANE countries indicated that both FDI inflows and trade openness impacted positively and significantly on the GDP per capita, while the impact of capital account openness was negative and significant. Consequently, the study is of the view that while it will be necessary for the SANE countries to upgrade their institutions in order to reap the benefits of financial openness, the Asian Tigers should stabilize their polity to improve their economy.
Keywords: Institutional quality, FDI, GDP per capita, Financial development, Trade openness, Asian Tigers.
JEL Classification: E02, F21, F43
TERAPI AKTIVITAS KELOMPOK SENAM REUMATIK LANSIA DI PANTI JOMPO AL-YUSUFIYAH
Authors: Harahap Mei Adelina , Rangkuti Juni Andriani 
Published: February 2023

Usia lanjut atau lanjut usia bukanlah merupakan suatu penyakit, meskipun hal tersebut dapat menimbulkan masalah sosial. Di beberapa negara, terutama di negara-negara maju umur harapan hidup telah bertambah panjang sehingga warga-warga yang berusia lebih dari 65 tahun juga bertambah. Adanya peningkatan jumlah penduduk usia lanjut tersebut menyebabkan perlunya perhatian pada para lansia agar lansia tidak hanya berumur panjang tetapi juga dapat menikmati masa tuanya dengan bahagia serta meningkatkan kualitas hidup mereka. Tanda-tanda masa tua disertai dengan adanya kemunduran-kemunduran kemampuan kerja panca indera, gangguan fungsi alat-alat tubuh, perubahan psikologi serta adanya berbagai penyakit. Dengan banyaknya perubahan yang terjadi pada lansia banyak pula masalah kesehatan yang dihadapi. Untuk mempertahankan kesehatan lansia-lansia tersebut perlu adanya upaya-upaya baik besifat perawatan, pengobatan, pola hidup sehat dan juga upaya lain seperti senam reumatik. Metode yang di gunakan ceramah dan kegiatan terapi aktivitas kelompok senaam reumatik lansia. Pelaksanaan di lakukan di Panti Jompo Al- Yusufiyah pada bulan Juni 2022 yang diikuti oleh 13 lansia yang menderita reumatik. Kegiatan ini terlaksana dengan dengan baik bahkan para peserta terlihat antusias dan mengharapkan kegiatan terapi aktivitas kelompok senam reumatik ini dapat dijadikan bukan hanya upaya menurunkan skala nyeri tapi juga dapat mencegahan kompikasi pada penderita reumatik.
Old age or old age is not a disease, even though it can cause social problems. In several countries, especially in developed countries, life expectancy has increased so that citizens aged over 65 years are also increasing. The increase in the number of elderly population causes the need for attention to the elderly so that the elderly not only live long but can also enjoy their old age happily and improve their quality of life. Signs of old age are accompanied by declines in the ability of the five senses, impaired function of the organs, psychological changes and the presence of various diseases. With the many changes that occur in the elderly there are also many health problems they face. To maintain the health of the elderly, it is necessary to make good efforts in the form of treatment, medication, a healthy lifestyle and also other efforts such as rheumatic gymnastics. The method used is lectures and group activity therapy activities for the elderly rheumatic gymnastics. The implementation was carried out at the Al-Yusufiyah Nursing Home in June 2022 which was attended by 13 elderly people suffering from rheumatism. This activity was carried out well and even the participants looked enthusiastic and hoped that the therapy activities of the rheumatism exercise group could be used not only as an effort to reduce the pain scale but also to prevent complications in rheumatism sufferers.
PENANAMAN DAN PEMANFAATAN TANAMAN TOGA PADA MASYARAKAT DI DESA PARSALAKAN
Authors: Insan Hafni nur , Nst Nurlaila , Harahap Febri 
Published: February 2023

Upaya Kesehatan Bersumberdaya Manusia merupakan wujud nyata peran serta masyarakat dalam pembangunan kesehatan sebagai pemicu kegiatan pemberdayaan masyarakat, salah satunya adalah TOGA (Tanaman Obat Keluarga). Tanaman obat keluarga (TOGA) merupakan tanaman yang bisa ditanam atau dibudidayakan di pekarangan rumah dan mempunyai manfaat sebagai obat-obatan herbal tradisional. Seiring berjalannya waktu dimana obat-obatan mahal untuk dibeli, masyarakat terdorong kembali menggunakan obat-obat tradisional yang boleh dikatakan bebas dari komponen bahan-bahan kimia yang memungkinkan dapat berakibat fatal bagi kesehatan tubuh. Nama kegiatan pengabdian masyarakat ini adalah Pemberdayaan Masyarakat ”Penanaman dan Pemanfaatan TOGA Pada Masyarakat di Desa Parsalakan”. Tujuan dari kegiatan ini adalah untuk meningkatkan pemahaman dan kemampuan masyarakat mengenai pemanfaatan TOGA. Metode yang digunakan dalam penelitian ini adalah penelitian kualitatif dengan menggunakan teknik pengumpulan data yaitu observasi, wawancara terstruktur, dan dokumentasi. Dari hasil penelitian tersebut peneliti menyimpulkan bahwa pemanfaatan tanaman obat ditengah-tengah kehidupan masyarakat Desa Parsalakan sudah menjadi tradisi leluhur dan merupakan warisan turun temurun hal tersebut karena tanaman obat yang digunakan memiliki khasiat dalam menyembuhkan penyakit. Adapun saran yang ditawarkan oleh peneliti kepada masyarakat Desa Parsalakan untuk membudidayakan tanaman obat keluarga untuk menghindari kepunahan dan hendaknya hasil penelitian ini dapat dijadikan sebagai sumber informasi tentang tanaman obat keluarga.
PENYULUHAN KESEHATAN TENTANG BULLYING PADA REMAJA DI SMAS TAMAN SISWA SUKADAMAI TAHUN 2022
Authors: Sst70 Juliana , Jahriani Nani , - Mahyunidar 
Published: February 2023

ABSTRAK

Salah satu bentuk kekerasan fisik dan emosional yang paling umum pada anak - anak dan remaja adalah perundungan atau bullying. Indonesia adalah salah satu negara yang diduga masih mengalami angka kejadian bullying cukup tinggi, seperti perilaku intimidasi dikalangan remaja. Secara fisik, pelaku bullying tidak hanya didominasi oleh anak yang berbadan besar dan kuat, anak bertubuh kecil maupun sedang yang memiliki dominasi yang besar, secara psikologis di kalangan teman-temannya juga dapat menjadi pelaku bullying. Alasan yang paling jelas mengapa seseorang menjadi pelaku bullying adalah bahwa pelaku bullying merasakan kepuasan apabila ia “berkuasa” di kalangan teman sebayanya. Berdasarkan data diperoleh dari siswa SMAS Taman siswa Sukadamai terdapat adanya bullying antar siswa namun tidak berdampak negatif kepada individunya. Dengan adanya kegiatan penyuluhan bullying siswa mulai memahami dampak negatif dari perilaku bullying. kepada siswa yang terlibat dalam situasi bullying di sekolah, agar tidak membiarkan temannya menjadi korban, sehingga diharapkan agar siswa lebih peka melihat situasi ini dan mengambil peran dalam menghentikan episode bullying di lingkungannya. Kepada pihak sekolah agar menerapkan pendidikan karakter yang berisi penanaman nilai-nilai moral sebagai salah satu wujud dari penanganan bullying.
PELAKSANAAN PENYULUHAN TENTANG BENCANA BANJIR DI BATUNADUA JULU KOTA PADANGSIDIMPUAN
Authors: Antoni Adi , Ahmad Haslinah 
Published: February 2023

Bencana adalah kejadian umum di dunia, dan penyebabnya mungkin alami, buatan manusia, teknologi, atau konflik antar kelompok manusia. Edukasi yang kurang mengenai pencegahan terjadinya banjir bandang menjadi salah satu faktor penyebab berisiko. Tujuan kegiatan Penyuluhan ini untuk memberikan edukasi kepada warga di daerah Lingkungan II kelurahan Batunadua Julu Kecamatan Padangsidimpuan Batunadua Kota Padangsidimpuan tentang pengetahuan terkait bencana banjir. Pengabdian masyarakat ini dilakukan dengan metode ceramah dan aplikasi Leaflet . Kegiatan ini dilakukan selama 2 jam pada Hari Rabu 14 Desember 2022 yang bertempat di daerah Lingkungan II kelurahan Batunadua Julu Kecamatan Padangsidimpuan Batunadua Kota Padangsidimpuan Sumatera Utara. Hasil yang didapatkan setelah kegiatan penyuluhan ini adalah peningkatan pengetahuan masyarakat di daerah Lingkungan II kelurahan Batunadua Julu Kecamatan Padangsidimpuan Batunadua Kota Padangsidimpuan Sumatera Utara akan pencegahan terjadinya bencana banjir bandang.
PENYULUHAN CARA MENGGOSOK GIGI YANG BENAR DI PERSIAPAN MIN 5 KOTA PADANGSIDIMPUAN TAHUN 2022
Authors: Sagala Nanda suryani , Napitupulu Mastiur napitupulu , Napitupulu Natar fitri , Daulay Nanda masraini 
Published: February 2023

Kebiasaan menyikat gigi dengan baik dan benar dapat mempengaruhi kebersihan gigi dan mulut untuk itu dihrapkan siswa/I agar memperhatikan kebersihan gigi dan mulut untuk mencegah terjadinya penumpukan sisa-sisa makanan.Dalam proses ini penyampaian metode penyuluhan yang digunakan adalah demonstrasi yaitu suatu cara penyajian,pengertian dan ide,diskusi dan tanya jawab yang dipersiapkan dengan teliti untuk memperlihatkan bagaimana cara melaksanakan suatu tindakan,adegan atau menggunakan suatu prosedur.Penyuluan ini di ikuti oleh siswa-siswi kelas 5 Persiapan MIN 5 Padangsidimpuan yang berjumlah 73 orang.Hasil penyuluhan didapatkan siswa-siswi melakukan demonstrasi menyikat gigi yang benar secara bersamaan. Siswa-siswi mampu mendemonstrasikan cara menyikat gigi dengan benar dan mampu memjelaskan cara menjaga gigi untuk meningkatkan kesehatan gigi.
APLIKASI SKRINING AUSDRISK (THE AUSTRALIAN TYPE 2 DIABETES RISK ASSESSMENT TOOL) MODIFIKASI PADA KARYAWAN UNIVERSITAS AUFA ROYHAN PADANGSIDIMPUAN
Authors: Ritonga Sukhri Herianto , Rangkuti Juni Andriani 
Published: February 2023

Jumlah penderita diabetes mellitus terus meningkat dari waktu ke waktu, termasuk diabetes mellitus tipe 2. Hal ini membutuhkan perhatian serius dari semua kalangan untuk mencegah pertambahan jumlah penderita diabetes mellitus ini. Salah satunya adalah melalui upaya deteksi dini pada masyarakat dengan kelompok usia kurang dari 40 tahun. Tujuan dari kegiatan ini adalah untuk mendeteksi penderita diabetes mellitus tipe 2 pada karyawan Universitas Aufa Royhan Padangsidimpuan. Metode pelaksanaan kegiatan ini adalah kegiatan pengabdian kepada masyarakat dengan pendekatan aplikasi skrining. Partisipan pada kegiatan ini adalah karyawan Universitas Aufa Royhan Padangsidimpuan yang berusia kurang dari 40 tahun dengan jumlah total yang terlibat adalah 21 orang. Instrumen yang digunakan dalam deteksi dini penderita diabetes mellitus tipe 2 ini AUSDRISK (The Australian Type 2 Diabetes Risk Assessment Tool). Hasil kegiatan ini adalah 8 orang partisipan (38,10%) memiliki resiko tinggi untuk menderita DM tipe 2. Kemudian setelah dikonfirmasi melalui pemeriksaan kadar gula darah sewaktu, diperoleh hasil bahwa 1 partisipan (12,5%) dari kelompok resiko tinggi terkonfirmasi telah menderita diabetes mellitus, sedangkan 6 partisipan (75%) dari kelompok resiko tinggi tersebut belum pasti DM. Skrining menggunakan AUSDRISK ini dapat menjadi upaya dalam pencegahan terjadinya DM tipe 2 pada kelompok usia kurang dari 40 tahun, sehingga dapat memberikan intervensi secepat mungkin pada kelompok yang memiliki resiko tinggi.