bluuebunny/crossref_metadata_2025_split huggingface dataset:
Benefits and Barriers of Technology for Home Function and Mobility Assessment: Perspectives of Older Patients With Blood Cancers, Caregivers, and Clinicians
Authors: Clancy Dillon D. , Revette Anna C. , Bahl Nupur E. , Ho Kristi T. , Manor Bradley , Testa Marcia A. , Dieli-Conwright Christina M. , Hshieh Tammy , Driver Jane A. , Abel Gregory A. , DuMontier Clark 
Published: April 2023

PURPOSE Advances in digital health technology can overcome barriers to measurement of function and mobility for older adults with blood cancers, but little is known about how older adults perceive such technology for use in their homes. METHODS To characterize potential benefits and barriers associated with using technology for home functional assessment, we conducted three semistructured focus groups (FGs) in January 2022. Eligible patients came from the Older Adult Hematologic Malignancies Program at Dana-Farber Cancer Institute (DFCI), which includes adults 73 years and older enrolled during their initial consult with their oncologist. Eligible caregivers were 18 years and older and identified by enrolled patients as their primary caregiver. Eligible clinicians were practicing DFCI hematologic oncologists, nurse practitioners, or physician assistants with ≥2 years of clinical experience. A qualitative researcher led thematic analysis of FG transcripts to identify key themes. RESULTS Twenty-three participants attended the three FGs: eight patients, seven caregivers, and eight oncology clinicians. All participants valued function and mobility assessments and felt that technology could overcome barriers to their measurement. We identified three themes related to potential benefits: making it easier for oncology teams to consider function and mobility; providing standardized, objective data; and facilitating longitudinal data. We also identified four themes related to barriers to home functional assessment: concerns related to privacy and confidentiality, burden of measuring additional patient data, challenges in operating new technology, and concerns related to data improving care. CONCLUSION These data suggest that specific concerns raised by older patients, caregivers, and oncology clinicians must be addressed to improve acceptability and uptake of technology used to measure function and mobility in the home.
Child of the Cranes
Authors: Bennett Steffani 
Published: April 2023

Abstract
The monk-painter Sesshū Tōyō (1420–ca. 1506) is among the most heralded of Japanese artists. This reputation is due in large part to his heroization in art-historical texts of the early modern period. Earlier scholarly emphasis on Sesshū's artistic individualism has obscured our understanding of the professional nature of his activity as a painter in service to a regional military clan. This article reexamines Sesshū's career through consideration of the pair of folding screens known as Birds and Flowers of the Four Seasons. As the only firmly attributed painting in this format in the painter's oeuvre, Birds and Flowers offers illuminating insight into the ways in which Sesshū performed the role of painter-in-attendance for the Ōuchi clan. Sesshū's travel to China as part of an official diplomatic delegation in the fifteenth century was the most defining experience of the painter's career. In style and subject matter, Birds and Flowers provides insight into Sesshū's encounter with imperial painting at the Ming academy during this time. This symbolic analysis also offers a fresh approach to deciphering the heretofore mysterious patronage context surrounding the screens.
The current role of nuclear medicine in breast cancer
Authors: Vaz Sofia C. , Oliveira Carla , Teixeira Ricardo , Arias-Bouda Lenka M. Pereira , Cardoso Maria João , de Geus-Oei Lioe-Fee 
Published: April 2023

Breast cancer is the most common cancer in females worldwide. Nuclear medicine plays an important role in patient management, not only in initial staging, but also during follow-up. Radiopharmaceuticals to study breast cancer have been used for over 50 years, and several of these are still used in clinical practice, according to the most recent guideline recommendations.
In this critical review, an overview of nuclear medicine procedures used during the last decades is presented. Current clinical indications of each of the conventional nuclear medicine and PET/CT examinations are the focus of this review, and are objectively provided. Radionuclide therapies are also referred, mainly summarising the methods to palliate metastatic bone pain. Finally, recent developments and future perspectives in the field of nuclear medicine are discussed. In this context, the promising potential of new radiopharmaceuticals not only for diagnosis, but also for therapy, and the use of quantitative imaging features as potential biomarkers, are addressed.
Despite the long way nuclear medicine has gone through, it looks like it will continue to benefit clinical practice, paving the way to improve healthcare provided to patients with breast cancer.
A polissemia do item lexical ‘cartão’ na ótica da Linguística Cognitiva e suas redes de sentido inerentes
Authors: Oliveira Guilherme Delgado 
Published: April 2023

Este trabalho insere-se na perspetiva da Linguística Cognitiva sob o descurtino da polissemia. Tem como finalidade analisar a polissemia do vocábulo ‘cartão’ em termos lexicográficos e da linguagem em uso. Por isso, através de um corpus linguístico, primeiramente, dicionarístico, discutem-se os sentidos enformadores do item a partir do seu protótipo. De seguida, tenta-se examinar através das primeiras 1000 ocorrências da plataforma CETEMPúblico os mútiplos sentidos que a palavra encerra numa ótica da linguagem experiencialista. Serve-se das análises empreendidas para a elaboração de duas propostas de redes de sentido das quais concluímos categoricamente que (i) a análise lexicográfica é mais restritiva enquanto a da linguagem em uso é mais produtiva e dinâmica; (ii) dois são os principais mecanismos concetuais envolvidos na construção desses sentidos múltiplos – a metáfora e a metonímia, sendo a primeira por similaridade e a segunda por contiguidade.
La batalla de la Fatarella, 1938. Museografia, iconografia, recreació i memòria. Un model transversal de recerca didàctica
Authors: Sospedra Rafel , Feliu Maria , Wilson Ann Elisabeth , Sebares Gemma , Hernàndez Mar 
Published: April 2023

El combat de Raïmats, succeït el darrer dia de la batalla de l’Ebre (15 de novembre de 1938) ha estat investigat des de diverses òptiques per part del grup de recerca DIDPATRI en una perspectiva interdisciplinar i transversal. La recerca va començar amb una petició de l’associació cívica Lo Riu el 2013 a la Universitat de Barcelona que van aconduir a una intensa campanya arqueològica en una clara dinàmica de recerca pública. En els anys posteriors i fins el 2018 les accions sobre Raïmats s’han multiplicat incorporant experiències sobre museografia a l’aire lliure; visites escolars; turisme de camps de batalla; recreació històrica i generació d’iconografia didàctica. Tot plegat la dinàmica no exhaurida, es contextualitza també en una dinàmica pedagògica d’investigació acció en la qual els plantejaments didàctics assoleixen protagonisme. L’experiència transversal de Raïmats incorpora també una vessant explícita de memòria en tant que el lloc s’ha convertit en un referent significatiu de la batalla de l’Ebre.
Les rutes de l’exili del MUME: una dècada connectant espais de memòria a la Catalunya transfronterera
Authors: González David 
Published: April 2023

Els espais de memòria del territori català transfronterer es reparteixen a nord i sud dels Pirineus i estan lligats a la història i la memòria de l’exili republicà, així com a d’altres episodis històrics relacionats com els fugits de la Segona Guerra Mundial, les fortificacions militars de frontera, o la mateixa Guerra Civil espanyola en directa relació amb el territori.Des de la seva apertura al públic al febrer de l’any 2008, el Museu Memorial de l’Exili – MUME de La Jonquera s’ha convertit en l’equipament cultural catalitzador de gairebé totes les iniciatives per a la recuperació i divulgació de la memòria de l’exili republicà. La presentació d’una solvent exposició permanent, una dinàmica programació d’exposicions temporals, la participació activa en activitats relacionades amb la recerca, així com un servei educatiu amb accions cada cop més consolidades, han fet arrelar al MUME dins el teixit social i cultural del país. D’entre totes les activitats dutes a terme de manera regular, les rutes de l’exili, nucli de l’oferta del museu a través del seu servei educatiu, són l’autèntic eix comunicadordel MUME amb el territori. Aquest article abordarà, de manera sintètica, l’anàlisi de les diferents rutes existents en el territori català transfronterer al voltant de la temàtica de l’exili. Des dels seus orígens com a proposta pedagògica a nivell universitari fins l’actual oferta consolidada del servei educatiu del MUME, es mostraran aquells espais establerts com a nodes, així com també seran mencionades les diferents narratives sorgidesde l’execució de les diverses rutes existents. El cas particular aquí analitzat referma la capacitat de les rutes per exercir com una eina molt valuosa per tal d’encetar diferents dinàmiques de valorització del patrimoni.
Factors influencing adoption of oral health promotion by antenatal care providers in Moyo district, North-Western Uganda
Authors: Lulu Patrick Madrama , Nanyingi Miisa 
Published: April 2023

Background
Oral health promotion (OHP) during pregnancy is an important global public health and basic human right issue related to quality of life. Several statements and guidelines have been published emphasizing the need for improved oral health care of pregnant mothers, prenatal care providers have missed this critical opportunity. In this study, we assessed factors influencing adoption of oral health promotion by antenatal care providers.

Materials and methods
A descriptive cross-sectional study design that employed both quantitative and qualitative data collection methods and analysis. 152 samples determined using Yamane’s 1967 and stratified sampling technique was used. Three FGDs and six KI interviews were held. Univariate, bivariate and multivariate analyses were done using SPSS (20.0) and ATLAS Ti for qualitative analysis.

Results
Adoption of OHP was low 28% (42). Factors influencing adoption were age of respondents (OR = 0.066, 95%CI = 0.009–0.465, p = 0.006*), level of care of health facility (OR = 0.050, 95%CI = 0.008–0.322, p = 0.002*), good understanding between dentists and ANC providers (OR = 0.283, 95%CI = 0.084–0.958, p = 0.042*), availability of practice guideline for OHP in ANC (OR = 0.323, 95%CI = 0.108–0.958, p = 0.043*), number of years at work (p = 0.084), being knowledgeable (OR = 2.143, 95%CI = 0.864–5.311, p = 0.100), having skills to advance OHP(OR = 0.734, 95%CI = 0.272–1.984, p = 0.542), Management being good at influencing new practices (OR = 00.477.734, 95%CI = 0.227–2.000, p = 0.477). More emphasis on national and local of oral health issues, continuous staff training on oral health, dissemination of National oral health policy (NOHP) were some of key issues that emerged from the qualitative results.

Conclusion
Adoption of OHP was low. This was attributed to age, number of years spent at work, level of health facility, having good understanding between dentists and ANC providers, availability of practice guidelines, dissemination of National oral health policy, continuous staff training. We recommend the current NOHP to be reviewed, develop prenatal OHC guidelines, enhance the capacity of ANC providers through training, collaboration with dentists and launch official adoption of OHP.
Increased malaria incidence following irrigation practices in the Endorheic Rift Valley Basin of Sidama Region, Ethiopia
Authors: Hawaria Dawit , Kibret Solomon 
Published: April 2023

Background
Water resource development practice such as irrigation is key to ensuring economic growth and food security in developing countries. However, unintended public health problems such as malaria linked to such development projects have been a concern. This study aimed to determine the impact of irrigation on malaria incidence and vector mosquito abundance in southern Ethiopia.

Methods
Eight years’ malaria morbidity data were extracted from the medical registers of health facilities in both irrigated and non-irrigated settings. Additionally, adult and larval malaria vector surveys were carried out in both irrigated and non-irrigated villages. The trend of malaria incidence, case distribution across age and sex, seasonality, parasite species proportion, and mosquito density were analyzed and compared between irrigated and non-irrigated villages.

Results
The result showed that annual mean malaria incidence was 6.3 higher in the irrigated (95% CI: 0.7–33.6) than in the non-irrigated villages (95% CI: 1.2–20.6). Although a remarkable declining trend in malaria incidence was observed for four successive years (2013–2017), a significant resurgence between 2018 and 2020 was noted following the introduction of irrigation schemes. The densities of adult Anopheles mosquitoes were 15-fold higher in the irrigated compared to non-irrigated villages. Of the total potential mosquito-breeding habitats surveyed, the majority (93%) were from irrigated villages.

Conclusion
Higher malaria incidence, adult Anopheles density, and mosquito-breeding habitat were recorded in the irrigated villages compared to non-irrigated villages. These observations have important implications for the effectiveness of existing malaria interventions. Environmental management could help reduce the breeding of malaria vector mosquitoes around irrigation schemes.
Race Against the Clock: An Atypical Cause of Abdominal Pain
Authors: Panagos Katherine , Clinton Joe , Ji Byung , Canakis Andrew , George Lauren 
Published: April 2023

ABSTRACT
Aortoenteric fistula is a rare medical emergency that carries a high risk of mortality. In cases that present without gastrointestinal bleeding, it can be difficult to accurately diagnose and, therefore, properly manage. This case depicts a patient who presented with diffuse abdominal pain and obstipation. After imaging, esophagogastroduodenoscopy, and surgery, he was found to have an aortoduodenal fistula with an infected graft. Our case highlights the importance of maintaining a high index of suspicion for an aortoenteric fistula in a patient with vague abdominal symptoms and a significant history of vascular grafts.
Crystal structure of baryte from Mine du Pradet (France)
Authors: Paulsen Christian , Galéa-Clolus Valérie , Pöttgen Rainer 
Published: April 2023

Abstract
BaSO4, orthorhombic, Pnma (no. 62), a = 8.8806(8) Å, b = 5.4539(5) Å, c = 7.1570(7) Å, V = 346.64(6) Å3, Z = 4, Rgt
(F
2) = 0.0141, wRref
(F
2) = 0.0329, T = 293 K.
RUNX3: A Location-oriented Genome Coordinator
Authors: Xu Tianshu , Liang Yancan , Huang Zhiquan , Huang Zixian 
Published: April 2023

Abstract
Transcription factors are key components in gene expression and are associated with various diseases. Transcription factors maintain the stability of gene transcription and cell function. Among the transcription factors, the Runt-related transcription factor (RUNX) family regulates growth and development in a tissue-specific manner and is involved in tumorigenesis. The function of an important member of the RUNX family, RUNX3, was shown to be closely related to its subcellular localization. Normally, RUNX3 promotes or represses gene transcription in the nucleus; however, when RUNX3 is restricted in the cytoplasm, RUNX3 fails to function and only has a minor effect o gene expression. Hence, the risk of tumorigenesis cannot simply be equated with the level of RUNX3 expression, which makes the diagnosis and treatment of cancer more complicated. The cytoplasmic localization of RUNX3 has been shown to be associated with a variety of tumors. Herein we have summarized the current information on RUNX3 mis-localization and RUNX3 promotion of tumorigenesis, thus providing new insight for future investigations to elucidate the mechanisms by which RUNX3 regulates tumorigenesis.
Radiotherapy-related insufficiency fractures and bone mineral density: what is the connection?
Authors: Chatzimavridou-Grigoriadou Victoria , Barraclough Lisa H , Kochhar Rohit , Buckley Lucy , Alam Nooreen , Higham Claire E 
Published: April 2023

Background
Radiotherapy-related insufficiency fractures (RRIFs) represent a common, burdensome consequence of pelvic radiotherapy. Their underlying mechanisms remain unclear, and data on the effect of osteoporosis are contradictory, with limited studies assessing bone mineral density (BMD) by dual-energy x-ray absorptiometry (DXA).

Methods
BMD by DXA (Hologic) scan and fracture risk following pelvic RRIF were retrospectively assessed in 39 patients (median age 68 years) at a tertiary cancer centre. Patient characteristics and treatment history are presented narratively; correlations were explored using univariate regression analyses.

Results
Additional cancer treatments included chemotherapy (n = 31), surgery (n = 20) and brachytherapy (n = 19). Median interval between initiation of radiotherapy and RRIF was 11 (7.5–20.8) and that between RRIF and DXA 3 was (1–6) months. Three patients had normal BMD, 16 had osteopenia and 16 osteoporosis, following World Health Organization classification. Four patients were <40 years at the time of DXA (all Z-scores > –2). Median 10-year risk for hip and major osteoporotic fracture was 3.1% (1.5–5.7) and 11.5% (7.1–13.8), respectively. Only 33.3% of patients had high fracture risk (hip fracture >4% and/or major osteoporotic >20%), and 31% fell above the intervention threshold per National Osteoporosis Guidelines Group (NOGG) guidance (2017). Higher BMD was predicted by lower pelvic radiotherapy dose (only in L3 and L4), concomitant chemotherapy and higher body mass index.

Conclusion
At the time of RRIF, most patients did not have osteoporosis, some had normal BMD and overall had low fracture risk. Whilst low BMD is a probable risk factor, it is unlikely to be the main mechanism underlying RRIFs, and further studies are required to understand the predictive value of BMD.
Management of hypertension during lenvatinib for advanced thyroid cancer: a suggested diagnostic and therapeutic algorithm
Authors: Colombo Carla , Ceruti Daniele , De Leo Simone , Bilo Grzegorz , Trevisan Matteo , Giancola Noemi , Moneta Claudia , Parati Gianfranco , Persani Luca , Fugazzola Laura 
Published: April 2023

Background
Hypertension (HTN) is the most frequent adverse event during treatment with lenvatinib (LEN), but data on its best management are limited.

Aim
The objective of this study was to assess incidence, features and best management of LEN-related HTN in a consecutive single tertiary-care centre cohort.

Methods
Twenty-nine patients were followed up for a mean time of 29.8 months (6–77 months).

Results
After a mean follow-up of 6.8 months, HTN was recorded in 76% of cases, as a de novo occurrence in half of them. HTN significantly correlated with LEN dose and was of grade 1, grade 2 and grade 3 in 5%, 50% and 45% of patients, respectively. The majority (77%) of patients with HTN developed proteinuria. There was no correlation between HTN and proteinuria or clinical features or best morphological response or any other adverse event (AE), with the exception of diarrhoea. Patients with or without pre-existing HTN or any other cardiovascular disease had a similar incidence of HTN during LEN, thus excluding the impact of this potential predisposing factor. After evaluation by a dedicated cardiologist, medical treatment was introduced in 21/22 patients (polytherapy in 20 of them). The most frequently used drugs were calcium channel blockers (CCBs) due to their effect on vasodilation. In case of poor control, CCBs were associated with one or more anti-hypertensive drug.

Conclusion
HTN is a frequent and early AE in patients on LEN treatment. We suggest a diagnostic and therapeutic algorithm to be applied in clinical practice to allow efficient HTN control and improve patient compliance, reducing LEN discontinuation.
The Terror-Famine Trauma Through the Narrative of Novella "Holodomor" by Yevhen Hutsalo
Authors: Maftyn Natalia 
Published: April 2023

One of the tasks of modern humanities, in particular Ukrainian one, is textualization of trauma as a memory that comes to life in “narratives of national identity”, since all the traumatic experience of previous generations, reflected on the mental map of Ukrainians, still remains not fully textualized, the whole situation is exacerbated by a new genocide, unleashed by Muscovy (Russia) against Ukraine. This article is devoted to the analysis of the novella “Holodomor” by Yevhen Hutsalo as a narrative of the collective trauma of the Holodomor, a terrible crime of the Moscow-Bolshevik dictatorship. The "trauma studies" methodology helps to research the narrative strategy, temporal-spacial modeling, ideological and literary sense of macro- and micro-images.
The work of Ye. Hutsalo was not written not by a direct eyewitness, yet it shows to way future generations inherit traumatic experience. The story's narrative focuses on the adherence to the historical and literary truths regarding the terrible "experiment" of the Moscow executioners and it is emphasized at the chronotope modeling level: " "tightness" of space horizontally - openness vertically; an exit from this locus of suffering is only through the grave. The author depicts the continent of the painful death of Ukrainian peasants, their struggle for life and for the salvation of their souls, the loss (or presence) of faith in the moral values that have been structuring their lives (the theocentric vertical) and all of that becomes a target of ruthless Moscow authorities who eagerly destroy everything, using food as a weapon.
Transitive Phenomena in the Grammatical System of the Language
Authors: Scherbii Natalia 
Published: April 2023

The article deals with the complex issue of transitivity in the parts of the language system, their morphological and syntactic characteristics, and functional variability. It describes the preconditions for the conversion transition, and in particular the peculiar verbal character of the Ukrainian language. The article also characterizes certain typological variants of conversion, in particular, among the so-called hybrid parts of speech – adjectives, infinitives, verb-turned nouns, the grammatical properties of which border on several parts of the language. The hybrid parts of language reveal syncretism at the morphological and semantic-syntactic levels. Transitive phenomena in the parts of speech also include exclamations, in particular verbal sound-imitations which are subject to transformation into an onomatopoeic verb. The article drives to conclusion that transitive phenomena in language testify to profound internal changes in both the semantic structure and the form of the word, and consequently denote the development and changes in the language.
Practical material is taken from the national corpora of the Ukrainian and Polish languages. Using examples from modern fiction and non-fiction, we have held a study of the phenomena of interaction and conversion responsible for semantic changes in words and their structural and grammatical peculiarities.