bluuebunny/crossref_metadata_2025_split huggingface dataset:
A clinical survey of the current status of difficult airway information dissemination
Authors: Shi Yun , Lan Dongyi , Zhang Song , Dong Chenbin 
Published: June 2023

Abstract
Background
Difficult airway is one of the greatest challenges faced by anesthesiologists and is a potential risk factor for increased fatality in patients. To date, there is no well-established and all-around difficult airway notification system in China, which has recently been recommended by existing guidelines to improve the care of patients with known difficult airways. This study aimed to investigate the status of critical information communication concerning difficult airway management and the current knowledge of the difficult airway notification system in our institute.
Methods
Vital information required to establish a difficult airway registry and notification system were collected through a literature review and expert suggestions. After approval by the Research Ethics Board, three online questionnaires were developed and sent to surgeons, anesthesiologists, and proxies of the patients. Knowledge of difficult airways and the status of difficult airway information dissemination among the three groups were investigated. The willingness of the participants to take part in the difficult airway registry and notification system was assessed.
Results
A significant difference was observed between what was expected and what was the reality to when the anesthesiologist retrieved the airway information of a patient with known airway difficulty. A significantly higher proportion of anesthesiologists would verbally disseminate airway information to the surgeons and other anesthesiologists, while a significantly higher proportion of anesthesiologists would disseminate airway information to the patients both verbally and in writing. Furthermore, a significantly higher proportion of anesthesiologists would communicate the detailed information to other anesthesiologists rather than to the patients or the surgeons. Most participants agreed with the necessity of setting up a difficult airway registry and notification system and were willing to take part in developing the system despite the significantly lower percentage in the patient group.
Conclusions
Difficult airway information is currently ineffective, which leads to a large gap between the expectation and reality of the anesthesiologist when caring for a patient with a difficult airway. Thus, a difficult airway registry and notification system that has a solid foundation for patients, surgeons, and anesthesiologists should be developed.
Trial registration:
The study was approved by the Research Ethic Board of Children’s Hospital of Fudan University and was registered at www.chictr.org.cn (registration number: ChiCTR2200063995).
The properties of black cherry tree wood (Prunus serotina Ehrh.) and its susceptibility to fungal decomposition in areas where it is secondary and invasive: a case study in the Kampinos National Park (Poland)
Authors: Marciszewska Katarzyna , Szczepkowski Andrzej , Lachowicz Hubert , Antczak Andrzej , Szadkowska Dominika , Suchodolski Jakub 
Published: June 2023

Abstract
The properties of black cherry wood and its susceptibility to fungal decay were studied in the secondary range of the species, on six trees from two stands growing in poor, acidic soils of the Albic Arenosol and Gleic Albic Podzol type, albeit differing in moisture and organic carbon and nitrogen content. Wood from trees growing in wetter and richer soils had better physical properties: of 95 determined parameters, 80 showed significant differences in favor of this wood – for example, wider rings (3.25 mm) on average and a higher density (662.71 kg/m3 at 12% humidity). The content of extractives in the wood of trees from more moist and rich soil plots was 1.5 times higher than in the case of trees grown in poorer and drier soil. Of 44 extractives determined by gas chromatography with mass spectrometry, six with confirmed antifungal properties were found in the wood of trees grown in wetter and richer soil, and only three in the wood of trees from drier and poorer soil: their percentage share was 62.93% and 8.68% of peak area respectively. This wood also turned out to be less susceptible to fungal decay: in general, however, the degree of decay was low, and of the four basidiomycete species tested, only Trametes versicolor caused a loss of more than 10% of wood mass in the samples from both sites. The obtained results show that black cherry has the ability to benefit from even small differences in the richness of generally poor soils and habitats to which it was introduced in the secondary range, resulting in the diversity of features and properties of its wood.
Prognostic value of peritoneal scar-like tissue in patients with peritoneal metastases of ovarian origin presenting for curative-intent cytoreductive surgery
Authors: Asmar Antoine El , Pop Florin , Helou Etienne El , Demetter Pieter , Veys Isabelle , Polastro Laura , Bohlok Ali , Liberale Gabriel 
Published: June 2023

Abstract

Background Complete cytoreductive surgery (CRS) ± hyperthermic intraperitoneal chemotherapy (HIPEC), remain the gold standard in the treatment of peritoneal metastases of ovarian cancer (PMOC). Given the increasing rate of neoadjuvant chemotherapy in patients with high PCI, prior abdominal surgeries, inflammation and fibrotic changes, the benefit of removing any “peritoneal scar-like tissues” (PST) during CRS, hasn’t been thoroughly investigated. Our objective in this retrospective cohort was to identify the proportion of malignant cells positivity in PST of patients with PMOC, undergoing curative-intent CRS ± HIPEC.Methods This is a retrospective study, conducted at our comprehensive cancer center, including patients with PMOC, presenting for curative-intent CRS. During CRS, benign-looking peritoneal lesions, lacking the typical hard nodular, aggressive, and invasive morphology, were systematically resected or electro fulgurated. PSTs were analyzed for the presence of tumoral cells by our pathologist. Correlations between the presence of PST and their positivity, and the different patients’ variables, were studied.Results In 51% of patients, PST harbored malignant cells. Those were associated with poorly differentiated serous tumors, a high PCI (> 8) and a worse DFS: 17 months in the positive PST group versus 29 months in the negative PST group (p = 0.05), on univariate analysis. Multivariate analysis revealed that PCI > 8 and poorly differentiated primary tumor histology were correlated with a worse DFS, and that higher PCI and advanced FIGO were correlated with a worse OS.Conclusion Benign-looking PST harbors malignancy in 51% of cases. The benefit of their systematic resection and their prognostic value should be further investigated in larger cohorts.
PD-L1-expressing cancer-associated fibroblasts induce tumor immunosuppression and contribute to poor clinical outcome
Authors: Kawasaki Kento , Noma Kazuhiro , Kato Takuya , Ohara Toshiaki , Tanabe Shunsuke , Takeda Yasushige , Matsumoto Hijiri , Nishimura Seitaro , Kunitomo Tomoyoshi , Akai Masaaki , Kobayashi Teruki , Nishiwaki Noriyuki , Kashima Hajime , Maeda Naoaki , Kikuchi Satoru , Tazawa Hiroshi , Shirakawa Yasuhiro , Fujiwara Toshiyoshi 
Published: June 2023

Abstract
The programmed cell death 1 protein (PD-1)/programmed cell death ligand 1 (PD-L1) axis plays a crucial role in tumor immune suppression, while the cancer-associated fibroblasts (CAFs) have various tumor-promoting functions. To determine the advantage of immunotherapy, the relationship between the cancer cells and the CAFs was evaluated in terms of the PD-1/PD-L1 axis. Overall, 140 cases of esophageal cancer underwent an immunohistochemical analysis of the PD-L1 expression and its association with the expression of the α smooth muscle actin (SMA), fibroblast activation protein (FAP), and the CD8, and forkhead box P3 (FoxP3) cells. The relationship between the cancer cells and the CAFs was evaluated in vitro, and the effect of the anti-PD-L1 antibody was evaluated using a syngeneic mouse model. A survival analysis showed that the PD-L1+ CAF group had worse survival than the PD-L1- group. In vitro and in vivo, direct interaction between the cancer cells and the CAFs showed a mutually upregulated PD-L1 expression. In vivo, the anti-PD-L1 antibody increased the number of dead CAFs and cancer cells, resulting in increased CD8+ T cells and decreased FoxP3 + regulatory T cells. We demonstrated that the PD-L1-expressing CAFs lead to poor outcomes in patients with esophageal cancer. The cancer cells and the CAFs mutually enhanced the PD-L1 expression and induced tumor immunosuppression. Therefore, the PD-L1-expressing CAFs may be good targets for cancer therapy, inhibiting tumor progression and improving host tumor immunity.
Non-Adherence with Physiotherapeutic Rehabilitation – A Cross-Cultural Adaption of Compliance Parameters into German
Authors: Hakam Hassan Tarek , Lettner Jonathan , Kersten Sebastian , Hofmann Hannes , Mühlensiepen Felix , Prill Robert , Becker Roland 
Published: June 2023

Abstract
Background: Compliance with rehabilitative physiotherapeutic measures leads to an improvement in outcomes in patients suffering from a variety of musculoskeletal conditions. Till date, a tool in assessing the parameters that lead to non-adherence to physical therapy does not exist in the German language. The objective of this paper is to cross-culturally adapt a non-compliance questionnaire to German.
Methods: In reference to the “Guidelines for the Process of Cross-Cultural Adaption of Self-Reported Measures”, the questionnaire was translated into German followed by a back-translation into the original language. An expert committee met and refined the pre-final version. A preliminary version was handed out to patients for the evaluation of the quality of the resulting German version. A simple statistical analysis was carried out to evaluate the final version.
Results: After the forward and back-translation of the questionnaire, some discrepancies were discovered between the translators on one hand and between the back translations and the original document on the other. The statistical analysis showed satisfactory results regarding the quality of the questionnaire.
Conclusion: The translation and adaption of the items proved to have a high degree of reliability. The German version will also be made available for other German-speaking researchers and used in the evaluation of a mobile application-based physical therapy regimen by the authors of the paper.
Registration: The objective of this paper is the cross-cultural adaption of a questionnaire. No registration was deemed necessary.
Lateral rectus approach versus ilioinguinal approach for acetabular fractures: A retrospective comparative study
Authors: Zhou Yue , Zhou Qingsong , Wang Shengtao , Zhao Ming , Cai Jieyong , Wang Heng , Li Zhengjiang , Deng Wei , Yin Yong 
Published: June 2023

Abstract
Background
The surgical management of acetabular fractures is challenging, and although new minimally invasive surgical approaches are being developed, the optimal surgical approach is still under discussion. We compared the clinical and radiographic findings of two surgical approaches for acetabular fractures: the lateral rectus approach (LRA) and the ilioinguinal approach (IA).
Methods
A consecutive cohort of 42 patients treated by a single surgeon using the LRA or IA from June 2015 to December 2018 with displaced acetabular fractures with a minimum 1-year clinical and radiographic follow-up were included. Clinical data were reviewed for fracture pattern, time to surgery, operative time, blood loss, quality of reduction, and perioperative complications. Fracture reduction quality was evaluated according to the Matta criteria. The Merle D’Aubigne-Postel and Harris Hip Score (HHS) were used for hip function outcomes.
Results
The complications, fracture reduction quality, Merle D’Aubigne-Postel score, and HHS were not significantly different between the approaches. There were statistically significant differences in the mean operative time (P = 0.003), intraoperative blood loss (P = 0.012), wound drainage (P = 0.031), and blood transfusion rate (P = 0.005) between the lateral rectus approach and the ilioinguinal approach.
Conclusion
Compared with the ilioinguinal approach, the lateral rectus approach is promising, especially for fractures in the quadrilateral area. The approach benefits fracture exposure, reduction, and fixation, thus shortening the operative time and reducing intraoperative bleeding.
Trial registration
Chinese Clinical Trial Registry, ChiCTR-2100043982, Registered on 6 March 2021
Level of Evidence: Level IV, retrospective comparative study.
Analysis of Cortical Spread Depression in Rats Induced to Hyperprolactinemia and Treated with Melatonin
Authors: Silva Ewerton Fylipe de Araújo , Gomes José Anderson da Silva , de Oliveira Maria Luísa Figueira , Noya Arthur Gabriel Alves Furtado de Carvalho , Magalhães Carolina Peixoto , Silva João Vitor da , Silva Luíz Henrique da , Tenório Bruno Mendes , Tenorio Fernanda das Chagas Angelo Mendes 
Published: June 2023

Abstract

Introduction: Cortical spreading depression (CSD) is an electrophysiological phenomenon used experimentally to analyze the direct modulation of the electrical activity of cortical neurons, and the dissemination of this wave may be associated with several pathological factors. Hyperprolactinemia is a pathological condition related to high plasma levels of prolactin, which, at normal levels, influences brain functions. However, high levels of this hormone can act differently in the cerebral cortex. Melatonin is an influential hormone in the central and peripheral nervous system, playing a cerebrovascular, neuroendocrine, neuroimmune and neuroprotector regulatory role.
Objectives: The objective was to analyze CSD in rats induced to hyperprolactinemia and treated with melatonin.
Results: 64 rats were used, which were divided into two treatment periods (30 and 60 days), subdivided into 4 groups each: Control, Vehicle, Hiper (rats induced to hyperprolactinemia) and Hiper+mel (rats induced to hyperprolactinemia and treated with melatonin). After treatment, the animals were anesthetized for analysis of the CSD propagation velocity, which was calculated based on the distance between the two recording electrodes, and the time spent by the CSD to cover this distance. The recording was performed at the two parietal points of the right cerebral hemisphere, for a continuous period of 4 hours. The ANOVA results of the animals treated for 30 days showed that the control group had an average speed of 3.43 ± 0.11 mm/min and the vehicle 3.10 ± 0.04 mm/min. In the Hyper group, the mean speed was 3.38 ± 0.16 mm/min, while the Hyper+mel group had a speed of 2.21 ± 0.02 mm/min. As for the animals treated for 60 days, the control group obtained a speed of 3.21 ± 0.22 mm/min, while the vehicle 3.06 ± 0.17 mm/min.
The hyper group 4.65 ± 0.16 mm/min and the hyper+mel 2.34 ± 0.19 mm/min. There was a significant increase in the hyper group compared to the others, and a significant decrease in the hyper+mel group compared to the other groups.
Conclusions:It is concluded that hyperprolactinemia has a direct effect on increasing the speed of CSD, on the other hand, the neuroprotective effects of melatonin were sufficient to establish efficiency against hyperprolactinemia.
A comprehensive investigation on the propagation properties of a Generalized Hermite cosh-Gaussian beam through atmospheric turbulence
Authors: Saad Faroq , Belafhal Abdelmajid 
Published: June 2023

Abstract
The impact of atmospheric turbulence on the properties of a Generalized Hermite cosh-Gaussian beam (GHCGB) is investigated. The formula for the average intensity of the propagated GHCGB in turbulent atmosphere is derived using the extended Huygens-Fresnel integral diffraction and Rytov method. Some graphical representations have examined to study the influences of turbulent atmosphere and incident beam parameters on the average intensity of the considered beam. Results show that the average intensity strongly depends on the structure constant of the turbulent atmosphere and the incident beam parameters such as the Gaussian waist width, the decentered cosh parameter and the beam orders. It’s shown that the initial profile of the beam remains unchanged within shorter propagation distance and spreads more rapidly on a Gaussian like distribution for the lager strong turbulent and the smaller beam parameters, but the reverse behavior will formed on a dark hollow distribution as the incident beam parameters are large. The paper results are useful for the atmospheric optics applications in remote sensing and free-space optical communications.
An Algebraic Optimization Model to Conserve Water Environment by Distributing Manure for Harvesting
Authors: Dione Déthié , Mbainaissem Teubé Cyrille , Koné Bakary 
Published: June 2023

Abstract
An overuse of manure on farmland creates a major environmental problem. When dumping more manure than the crops need as fertilizer, it causes an excess of manure in those fields. Rainwater drains these excessive amounts from the surface into the water reservoirs (rivers and lakes), where they pollute the water, nourish algae, and harm the fish. We develop an algebraic optimization model to formulate for the selection of the right field at the right time so that the environmental damage is limited. We gather instance data from a region of topologically connected reservoirs in northern Senegal and their adjacent farmlands. This mathematical problem then can be tackled by standard solvers for linear optimization problems. When applied in practice, this solution can improve the water quality by reducing the amount of manure and its main components, Nitrogen, Phosphorus, and Potassium.
Generation of doughnut Humbert beam by a gradient-index medium
Authors: Nossir N. , Dalil-Essakali L. , Belafhal A. 
Published: June 2023

Abstract
In this paper, we generate a new doughnut Humbert beam from a Whittaker-Gaussian (WG) beam propagating through a gradient-index medium (GIM). Based on the extended Huygens-Fresnel diffraction integral, the analytical expression of the intensity distribution for doughnut Humbert beam is derived and discussed through numerical examples. The obtained results indicate that the diffracted beam evolves periodically versus the propagation distance in GIM and its behavior depends interestingly on the beam initial parameters and the gradient-index parameter. Our results can be useful for some applications such as in multi-dimensional optical manipulation, remote sensing domain and imaging.
High-Fat Diet and Vitamin D Effects on Contractile Performance of Isolated Mouse Soleus and EDL
Authors: Shelley Sharn P. , James Rob S. , Eustace Steven J. , Eyre Emma L.J. , Tallis Jason 
Published: June 2023

Abstract
Evidence suggests vitamin D (VD) could mitigate adverse effects of obesity on skeletal muscle (SkM) function, however, this is yet to be directly investigated. Therefore, this study used the work-loop technique to examine effects of high dose dietary VD supplementation on contractile performance of isolated SkM. Female mice (N = 37) consumed standard (SLD) or high-fat diet (HFD), with or without VD (20,000 IU/kg− 1) for 12-weeks. Soleus and EDL (N = 8–10) were isolated and absolute and normalised (relative to muscle size and body mass) isometric force and power output (PO) were measured, and fatigue resistance determined. Absolute and normalised isometric force and PO of the soleus were unaffected by diet (P > 0.087). However, PO normalised to body mass was reduced in HFD groups (P < 0.001). Isometric force of the EDL was unaffected by diet (P > 0.588). HFD evoked reduced EDL isometric stress (P = 0.048) and absolute and normalised PO (P < 0.031), but there was no effect of VD (P > 0.493). Cumulative work during fatiguing contractions was lower in HFD treated SkM (P < 0.043), but the rate of fatigue was unaffected (P > 0.060). This study uniquely demonstrated that high dose dietary VD had limited effects on SkM contractile function and did not offset the demonstrated adverse effects of HFD. However, there was non-significant small and moderate effects suggesting improvement in EDL muscle performance and animal morphology in HFD VD groups. Given trends observed, coupled with the proposed inverted U-shaped dose-effect curve, future investigations are needed to determine dose/duration specific responses to VD, which may culminate in improved function of HFD treated SkM.
The clinical features of patients who underwent bladder augmentation of cloacal exstrophy and their functional outcomes: The results of a nationwide survey in Japan
Authors: Yano Keisuke , Sugita Koshiro , Kawano Takafumi , Murakami Masakazu , Harumatsu Toshio , Onishi Shun , Yamada Koji , Muto Mitsuru , Ieiri Satoshi , Kubota Masayuki 
Published: June 2023

Abstract
PURPOSE
Cloacal exstrophy (CE) patients may need bladder reconstruction after initially undergoing surgery to obtain continence and improve their quality of life. This study attempts to clarify the clinical features of CE patients who underwent bladder augmentation (BA) and their urinary functional outcomes based on a nationwide survey in Japan.
METHODS
A questionnaire survey was conducted, and 150 CE patients were enrolled. Their clinical characteristics and urinary outcomes were reviewed.
RESULTS
BA was performed in 52 patients (34.7%). Most cases underwent early bladder closure at initial surgery in neonate period. The age at the BA was performed 6.4 [6–9.0] years old. Among them, the most used organ for BA was ileum (n = 30, 57.7%). Regarding the outcomes, the age when the renal function was evaluated was 14.0 [10.0–20.5] years old and the serum creatinine level was 0.44 [0.36–0.60] (mg/dl). Clean intermittent catheterization was required in 37 (71.2%) patients. On the other hand, no dialysis or kidney transplantation was necessary in any of these patients.
CONCLUSION
The renal function and conditions of patients who underwent BA were relatively well preserved. Individualized management with a stepwise surgical approach for CE patients should thus be considered in the future.
Two classes of inverse problems for dual matrices
Authors: Fan Ranran , Zeng Min , Yuan Yongxin 
Published: June 2023

Abstract
Dual matrices play an important role in robotics, kinematic analysis, spatial synthesis mechanisms, and so on. In this paper, two classes of inverse problems for dual matrices are discussed and the solvability conditions and the general solutions are achieved by applying the singular value decomposition and the generalized inverse. Further, the corresponding approximation problems are considered and the optimal approximate solutions are deduced by using some matrix decompositions and the Kronecker product. Finally, a numerical example is presented to verify the correctness of our results.
15A24, 65F18