bluuebunny/crossref_metadata_2025_split huggingface dataset:
Performing Symmetry in Andean Weather Forecasting: The Practice of Cabañuelas, Beyond Divination and Suffering
Authors: Legoas P Jorge 
Published: June 2023

Abstract
This paper analyzes a practice known as Cabañuelas—an Indigenous way of anticipating the next year’s rainfall by interpreting a series of signs in the current year. The knowledge and gestures associated with this practice have traditionally been understood according to the classical division between pragmatic techniques and magic rituals, an approach that I set aside in favor of considering Cabañuelas as a hybrid practice involving multiple kinds of beings and agents. It can also be understood as part of a complex of practice together with the offerings to the earth in August, and in addition to the reading of the coca leaf and the molten lead—all of these being practices that share an observational, prospecting, and performative character. Based on this, I put forward the idea of empowered agents, challenging the view of suffering Andean actors hopelessly subjected to super/natural forces or idiosyncratic conditions they cannot control.
Effects of dietary zinc/copper ratios on the metabolism of zinc and copper in weaned pigs
Authors: Dalto Danyel Bueno , Audet Isabelle , Roy Caroline , Deschêne Karine , Villeneuve Geneviève , Matte J Jacques , Lapointe Jérôme 
Published: June 2023

AbstractThis study compared the effects of different dietary zinc/copper ratios on zinc (Zn) and copper (Cu) metabolism in weaned pigs. One hundred and sixty piglets (7.81 ± 0.25 kg; 21 d of age) were used in a completely randomized 2 × 2 factorial design composed with high (H) and low (L) levels of added dietary Zn (100 and 3,000 mg/kg) and dietary Cu (6 and 130 mg/kg). Piglets were slaughtered at 21, 28, 35, and 42 d of age for blood and tissues collection. Serum, jejunum mucosa, liver, and kidney concentrations of Zn and Cu were analyzed as well as tissues mRNA abundance of genes related to their metabolism. Serum and liver Zn concentrations increased at days 28, 35, and 42 in HZn groups compared to pre-treatment levels (day 21; P ≤ 0.01) but for LZn animals, values decreased at days 28, 35, and 42 in liver (P ≤ 0.01) but remained stable vs. day 21 levels in serum (P ≥ 0.37). Serum, jejunum mucosa, liver, and kidney Zn concentrations were greater in HZn groups from day 28 (P ≤ 0.01). In jejunum mucosa, the mRNA expression of ZIP4 was lower in HZn piglets at day 28 (P ≤ 0.01) and at day 42 whereas HCu supplementation increased ZIP4 expression in LZn but not in HZn diets (P = 0.05). For ZNT1, MT3, and MT1, values of relative mRNA expression were greater for HZn animals in jejunum mucosa, liver, and kidney (P ≤ 0.01) from day 28. In kidney (P &lt; 0.01) at day 42, HZn supplementation increased MTs expression in both LCu or HCu groups. Serum and liver Cu concentrations decreased at days 35 and 42 in all treatments compared to day 21 (P ≤ 0.04), except LZnHCu in liver that was not different from day 21 (P ≥ 0.17). Serum Cu concentrations were lower in HZn and greater in HCu groups at days 35 and 42 (P ≤ 0.01) whereas hepatic Cu was reduced by HZn diets in both LCu and HCu groups at days 35 and 42 (P ≤ 0.01). Jejunum Cu concentrations were increased by HCu diets in HZn but not in LZn groups at days 28 and 42 (P ≤ 0.04). Renal Cu concentrations were greater in HZn groups at day 28 (P &lt; 0.01) whereas at day 42 HZn diets increased Cu values in both LCu and HCu groups (P ≤ 0.01). The expression of ATP7A in kidney at day 42 was greater for HZn groups (P = 0.02). In conclusion, high dietary Zn levels were not efficiently regulated by homeostatic mechanisms and significantly impaired Cu homeostasis. Low dietary Zn/Cu ratios allow a more efficient regulation of the metabolism of these trace minerals in post-weaning piglets. The current official recommendations for Zn and Cu to post-weaning piglets apparently do not fulfill their requirements.
Structural insights into a bacterial β-glucosidase capable of degrading sesaminol triglucoside to produce sesaminol: toward the understanding of the aglycone recognition mechanism by the C-terminal lid domain
Authors: Yanai Taro , Takahashi Yukino , Katsumura Eri , Sakai Naoki , Takeshita Kohei , Imaizumi Riki , Matsuura Hiroaki , Hongo Shuntaro , Waki Toshiyuki , Takahashi Seiji , Yamamoto Masaki , Kataoka Kunishige , Nakayama Toru , Yamashita Satoshi 
Published: June 2023

Abstract
The sesaminol triglucoside (STG)-hydrolyzing β-glucosidase from Paenibacillus sp. (PSTG1), which belongs to glycoside hydrolase family 3 (GH3), is a promising catalyst for the industrial production of sesaminol. We determined the X-ray crystal structure of PSTG1 with bound glycerol molecule in the putative active site. PSTG1 monomer contained typical three domains of GH3 with the active site in domain 1 (TIM barrel). In addition, PSTG1 contained an additional domain (domain 4) at the C-terminus that interacts with the active site of the other protomer as a lid in the dimer unit. Interestingly, the interface of domain 4 and the active site forms a hydrophobic cavity probably for recognizing the hydrophobic aglycone moiety of substrate. The short flexible loop region of TIM barrel was found to be approaching the interface of domain 4 and the active site. We found that n-heptyl-β-D-thioglucopyranoside detergent acts as an inhibitor for PSTG1. Thus, we propose that the recognition of hydrophobic aglycone moiety is important for PSTG1-catalyzed reactions. Domain 4 might be a potential target for elucidating the aglycone recognition mechanism of PSTG1 as well as for engineering PSTG1 to create a further excellent enzyme to degrade STG more efficiently to produce sesaminol.
Managing collapsed boundaries in global work
Authors: Sivunen Anu , Gibbs Jennifer L , Leppäkumpu Jonna 
Published: June 2023

AbstractGlobal workers have long contended with the challenges of working across geographical, temporal, and cultural boundaries enabled by communication technologies. However, the global work research has rarely intersected with the literature on work–home boundary management—which has been brought to the forefront due to the forced move to remote work during the Covid-19 pandemic. Drawing on a qualitative field study of 55 in-depth interviews with global workers from a large organization headquartered in the Nordics, we found that global workers drew on sociomaterial affordances to manage both global work and work–home boundaries through strategies of boundary support and boundary collapse. Although the shift to remote work created challenges due to boundary collapse, it presented new spatiotemporal affordances that led to unexpected benefits for both global work and work–life boundary management. The findings have implications for global work, remote work, and the future of work more broadly.
Positioning in a collaboration network and performance in competitions: a case study of Kaggle
Authors: Twyman Marlon , Murić Goran , Zheng Weiwei 
Published: June 2023

Abstract
Online innovation competitions are ecosystems where institutions source numerous solutions from knowledge workers through a platform intermediary. By considering how an individual competitor’s performance varies based on their social positioning in a competition ecosystem’s collaboration network, we illustrate the value of social networks for individual outcomes in online competitions. The study reports results from Kaggle, a popular online competition platform for data science, where a sample of 350,956 users participated in 2,789 competitions over 4 years. We investigate how the number of collaborations, membership in the largest connected component in the network, and diversity of collaboration experiences impact the points and medals earned and how quickly competitors earn their first medal. Results show that positioning has a positive relationship with performance in competitive ecosystems. Relevant to the future of work, the study considers how knowledge workers in future workplaces should manage their online collaborations.
Reducing the low-wavenumber dispersion error by building the Lagrange dual problem with a powerful local restriction
Authors: Peng Weiting , Huang Jianping , Shen Yi 
Published: June 2023

Abstract
The broadband finite-difference (FD) coefficients computed by a cost function have been widely applied to suppress of numerical dispersion. Under the same conditions, the FD coefficients with small low-wavenumber dispersion error will produce a more accurate numerical solution in the long-time seismic wave simulation. Thus, how to reduce the low-wavenumber dispersion error becomes a crucial problem. According to the research into the zero-point position at the dispersion curve for three types of cost function, we found that the more zero points concentrate on the low-wavenumber region, the less the dispersion error. Therefore, the concentration of zero points is a good way to reduce dispersion error, which can be implemented by modified wavenumbers of zero points. Then, we design a Lagrange dual problem with a restriction based on the modified wavenumbers. The requirements for constructing the Lagrange dual problem are the optimization function and restricted condition, where the former is based on the dispersion relation, and the latter comprises the modified wavenumbers. The solution of this optimization problem, calculated by the dual ascent method, affords a less low-wavenumber dispersion error than the solution yielded by the alternating direction method of multipliers (ADMM). The theoretical analysis and numerical modeling suggest that the proposed method is superior to the existing optimal FD coefficients in reducing numerical error accumulation in low-frequency simulation.
A computational approach for positive genetic identification and relatedness detection from low-coverage shotgun sequencing data
Authors: Nguyen Remy , Kapp Joshua D , Sacco Samuel , Myers Steven P , Green Richard E 
Published: June 2023

Abstract
Several methods exist for detecting genetic relatedness or identity by comparing DNA information. These methods generally require genotype calls, either single-nucleotide polymorphisms or short tandem repeats, at the sites used for comparison. For some DNA samples, like those obtained from bone fragments or single rootless hairs, there is often not enough DNA present to generate genotype calls that are accurate and complete enough for these comparisons. Here, we describe IBDGem, a fast and robust computational procedure for detecting genomic regions of identity-by-descent by comparing low-coverage shotgun sequence data against genotype calls from a known query individual. At less than 1× genome coverage, IBDGem reliably detects segments of relatedness and can make high-confidence identity detections with as little as 0.01× genome coverage.
Neutrophil responsiveness to IL-10 impairs clearance of Streptococcus pneumoniae from the lungs
Authors: Horn Kadi J , Fulte Sam , Yang Michael , Lorenz Brian P , Clark Sarah E 
Published: June 2023

Abstract
The early immune response to bacterial pneumonia requires a careful balance between pathogen clearance and tissue damage. The anti-inflammatory cytokine interleukin (IL)-10 is critical for restraining otherwise lethal pulmonary inflammation. However, pathogen-induced IL-10 is associated with bacterial persistence in the lungs. In this study, we used mice with myeloid cell specific deletion of IL-10R to investigate the cellular targets of IL-10 immune suppression during infection with Streptococcus pneumoniae, the most common bacterial cause of pneumonia. Our findings suggest that IL-10 restricts the neutrophil response to S. pneumoniae, as neutrophil recruitment to the lungs was elevated in myeloid IL-10 receptor (IL-10R)–deficient mice and neutrophils in the lungs of these mice were more effective at killing S. pneumoniae. Improved killing of S. pneumoniae was associated with increased production of reactive oxygen species and serine protease activity in IL-10R–deficient neutrophils. Similarly, IL-10 suppressed the ability of human neutrophils to kill S. pneumoniae. Burdens of S. pneumoniae were lower in myeloid IL-10R–deficient mice compared with wild-type mice, and adoptive transfer of IL-10R–deficient neutrophils into wild-type mice significantly improved pathogen clearance. Despite the potential for neutrophils to contribute to tissue damage, lung pathology scores were similar between genotypes. This contrasts with total IL-10 deficiency, which is associated with increased immunopathology during S. pneumoniae infection. Together, these findings identify neutrophils as a critical target of S. pneumoniae-induced immune suppression and highlight myeloid IL-10R abrogation as a mechanism to selectively reduce pathogen burdens without exacerbating pulmonary damage.
Sustainability Agreements and First Mover Disadvantages
Authors: Paha Johannes 
Published: June 2023

Abstract
This article presents a model where the managers of two firms decide about adopting a sustainable production technology (or product). It demonstrates under what conditions a firm experiences a first mover disadvantage from going green, which may potentially be overcome by a sustainability agreement serving as a device for equilibrium selection in a coordination game with multiple equilibria. If the technology adoption game is, however, a prisoner’s dilemma, the sustainability agreement must be structured like a hardcore cartel.
Recurrence of digital papillary invasive adenocarcinoma
Authors: Chaudhry Nadeem , Qureshi Abid , Shah Rutva , Razzaq Asad , Clopton Brittni J , Genato Romulo , Xiao Philip 
Published: June 2023

Abstract
Adenocarcinoma is extremely uncommon in the digits with an incidence of 0.08 per 1 000 000 people per year, known as digital papillary adenocarcinoma (DPA). This disease is commonly described pathologically as malignancy of the sweat glands. The fundamental histologic characteristics of DPA are the presence of papillary projections in cystic spaces in a multinodular tumor lined by epithelial cells. DPA are often delayed in diagnosis because of either misdiagnosis for benign lesions or underreporting, which can contribute to poor prognosis and metastasis. This report serves to present a case of recurrence observed in primary digital adenocarcinoma and to bring awareness to the topic as concrete management continues to develop.
Double free flaps for complex oromandibular defects with two teams of head and neck reconstructive surgical oncologists
Authors: Nguyen Khoi A 
Published: June 2023

Abstract
From December 2019 to July 2021, double free flaps were used by two teams of head-and-neck reconstructive surgical oncologists in 10 patients with large composite mandibulofacial defects following malignant tumor (n = 8) and osteoradionecrosis (n = 2) ablation. Our report included 10 patients. All of our patients were reconstructed by two free flaps, a combination of an anterolateral thigh flap (n = 8) or a radial forearm flap (n = 2) with an osteocutaneous fibula flap. The survival rate of these flaps was 100%. The mean operative time was 597 ± 41.7 min (range 545–660 min). There were no patients with major complications. Most of our patients had accepted functional and cosmetic results of both recipient site and donor site after a median follow-up of 22.5 months. Two teams of reconstructive surgical oncologists may shorten the operative time and reduce the rate of major complications.
Main Points:
Huge complex oromandibular defects may require the use of double free flap reconstruction. Double free flaps were used by two teams of head-and-neck reconstructive surgical oncologists. This approach may shorten the operative time and reduce the rate of major complications.
(038) Sexual Issues Due to Comorbidities in Individuals with Fetal Alcohol Spectrum Disorder
Authors: Collins K , Bachmann G 
Published: June 2023

Abstract

Introduction
Fetal alcohol spectrum disorder (FASD) is used to describe the range of conditions associated with prenatal alcohol exposure. FASD is characterized by growth deficits, facial dysmorphia and central nervous system abnormalities. When an individual with an FASD remains undiagnosed and proper interventions are not instituted, secondary disabilities are common. Prenatal exposure to alcohol affects the individual’s development, cognition and learning, which results in characteristic ways of thinking and behaving. Deficits can range from mild cognitive deficits such as subtle effects on executive function, memory and adaptive behavior to profound intellectual disability and severe behavioral problems that result from poor self-regulation.

Objectives
To examine adverse life outcomes regarding sexual behavior in individuals with FASD.

Methods
A literature search was performed using keywords relating to Fetal Alcohol Spectrum Disorder, FASD Development, FASD Cognition and FASD Sexual issues.

Results
Findings showed that one of the strongest correlates of adverse life outcomes including inappropriate sexual behaviors was lack of an early diagnosis. The longer FASD went undiagnosed, the greater the odds of adverse outcomes. One study that examined 415 subjects with FASD of ages ranging from six to fifty-one noted that inappropriate sexual behaviors was the most frequent adverse life outcome increasing with age. Inappropriate sexual behavior was defined by sentencing to a sexual offending treatment program or a persistent pattern of encounters with at least one of these sexual behaviors: obscene phone calls, sex with animals, voyeurism, incest, masturbation in public, compulsions, exposure, promiscuity, sexual advances, and sexual touching. It was concluded that symptoms of FASD may make it challenging to distinguish between inappropriate and appropriate sexual behaviors due to functional and cognitive deficits. For the same reasons, individuals with FASD do not generally improve after standard cognitive behavioral programming for addressing sexually inappropriate behaviors.

Conclusions
There has been very little empirical research on the role of FASD in inappropriate sexual behavior. In addition, environmental factors associated with prenatal alcohol exposure may play a role in the increased incidence of inappropriate sexual behaviors. One study that examined inappropriate sexual behaviors in individuals with FASD found that almost all the females in the study that exhibited these behaviors had also experienced physical, sexual abuse or violence against themselves. Additionally, half of them had alcohol or drug related issues. Further research into sexual issues related to FASD is required to confirm causality in findings so far.

Disclosure
No.
Spinal Cord Stimulation
Authors: Boggan James E. 
Published: June 2023

Abstract
Spinal Cord Stimulation: Percutaneous Implantation Techniques covers percutaneous applications and neuromodulation, which are primarily used for therapeutic effects on human behavior, function, and perception. Moreover, neuromodulation refers to the alteration of neuronal activity by chemical, electromagnetic, or optical stimulation. Physicians manage chronic pain through neuromodulation via electrical stimulation of the central and peripheral nervous systems. Using a minimally invasive, reversible, and non-addicting modality is proven to significantly reduce chronic pain, which often moderates autonomic dysfunction for appropriate patients. The book also addresses patient selection, stimulation targeting disease processes, training in managing chronic pain and neuromodulation techniques, and clinical decision-making.
The Development of Spinal Cord Stimulation
Authors: Kreis Paul G. , Hills Ammon A. , Fishman Scott M. 
Published: June 2023

Abstract
This chapter covers the development of spinal cord stimulation (SCS), which is known to be a well-established therapy for certain types of chronic pain. Moreover, SCS is a non-destructive and mostly reversible treatment since it does not change a patient’s anatomy. Unified resources for SCS remain limited as the information has been dispersed across the literature of numerous disciplines, such as pain medicine, anesthesiology, and neurosurgery. The chapter also discusses the gate theory of pain reduction, which suggests that pain is a complex neurologic and perceptual phenomenon to be modulated. It recognizes the broad categories of pain: nociceptive, neuropathic, and idiopathic.
Complications and Adverse Events
Authors: Singh Naileshni S. , Kreis Paul G. , Fishman Scott M. 
Published: June 2023

Abstract
This chapter tackles the complications and adverse effects recorded following surgery. As patients become increasingly informed and demand assurance for the best care possible, it is possible for patients to pick their provider based on comparative and public data on complication rates and post-operations. Future implanters are encouraged to be prepared regarding avoiding and managing complication when it occurs. To prevent harm to patients, advanced training and seasoned clinical judgment are needed to implant a spinal cord stimulator (SCS). The chapter lists anesthetic, surgical, and hardware complications as the complications linked with SCS. It recognizes wound dehiscence as one of the most dreaded complications of surgeons.
“A Person Is a Person Through Other Persons”
Authors: Di Nicola Vincenzo 
Published: June 2023

Abstract
A critical issue for the field is how to define contemporary social psychiatry for the present day. This chapter addresses this definitional task by breaking it down into three major questions for social psychiatry: (1) What is social about psychiatry? The chapter addresses definitional problems that arise, such as binary thinking, and the need for a common language. (2) What are the theory and practice of social psychiatry? Issues include social psychiatry’s core principles, values, and operational criteria; the social determinants of health and the Global Mental Health Movement; and the need for translational research. This part of the review establishes the minimal criteria for a coherent theory of social psychiatry and the view of persons that emerges from such a theory: the social self. (3) Why has the time come for a manifesto for social psychiatry? The author outlines the parameters for a theory of social psychiatry, based on both the social self and the social determinants of health, to offer an inclusive social definition of health, concluding with a call for action, a manifesto for 21st-century social psychiatry.
A Case Series of Ocular Syphilis Cases at Military Treatment Facility From 2020 to 2021
Authors: Kautz Michelle , Kerbow Christa , Lee Tida , Kronmann Karl C , Dore Michael 
Published: June 2023

ABSTRACT
Syphilis is a sexually transmitted infection, caused by the spirochete Treponema pallidum, that can lead to multi-organ involvement. In 2020, over 138,000 cases were reported in the United States equating to a case report of 40.8 per 100,000 people. Ocular syphilis is a rare manifestation and is defined as the clinical presentation of ocular disease in a person with laboratory-confirmed syphilis infection of any stage, with estimated incidence of 0.6–2% of all cases. Syphilis is known as “The Great Imitator,” and can present as nearly any form of ocular disease, though the most common manifestations are posterior uveitis and panuveitis. The highly variable clinical presentation of ocular syphilis often leads to delayed diagnosis allowing the potential for poor, often preventable outcomes. This highlights the need for providers to have a high level of clinical suspicion and awareness of ocular manifestations of syphilis, especially in high risk populations. We present a case series of five patients diagnosed with ocular syphilis at a military treatment facility. Each patient had different presenting symptoms as well as different ocular manifestations.