bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thermal management using nano coated heat sink for electric vehicle battery cooling
Authors: Thanigaitambi Rajmohan , Ramesh S. , Arulprakasajothi Mahalingam , Devarajan Yuvarajan , Sundaram Madhu , Subbaiyan Naveen 
Published: April 2023

AbstractTransient heat transfer occurs in a wide array of heat exchange devices and those subjected to heat input. Effective control of heat energy during transient heat transfer is vital to increase the operating life and effectiveness of the device and equipment subjected to the heating and cooling cycle. Extended surfaces in the form of pin fins are used to augment cooling in applications like electric vehicle batteries, computers, transformers, drones, and microcontrollers. In this study, an attempt is made to examine the heating and cooling cycle, the time required to attain a target temperature, and the enhancement ratio of finned heat exchangers. The heat sink is provided with graphene nanocoating intended for electric vehicle battery cooling. The performance of the heat sink and its counterparts having two different types of pin fins, that is, circular and square, are compared. Four different heat inputs were considered, that is, 15, 25, 35, and 45 W. Three different target temperatures, that is, 46, 56, and 66°C, were accounted for during the comparison. It is concluded that the graphene nanoparticles facilitated enhanced heat transfer during the heating cycle when the input heat was 25 W and above. The square pin fins exhibited an enhancement ratio of 1.5, irrespective of the input heat energy.
The effects of Avemar treatment on feline immunodeficiency virus infected cell cultures
Authors: Tarcsai Katalin Réka , Hidvégi Máté , Corolciuc Oliga , Nagy Károly , Abbas Anna Anoir , Ablashi Dharam V. , Kövesdi Valéria , Ongrádi József 
Published: April 2023

AbstractIntroductionIn addition to standard highly active antiretroviral therapy protocols, complementary therapies using natural compounds are widely used by human immunodeficiency virus (HIV)‐infected human patients. One such compound is the fermented wheat germ extract (FWGE), named Avemar.Materials and methodsIn this study, we investigate the effects of Avemar in a feline‐acquired immunodeficiency syndrome model. MBM lymphoid cells were acutely infected by the American feline immunodeficiency virus (FIV)‐Petaluma (FIV‐Pet) and the European FIV Pisa‐M2 strains. FL‐4 lymphoid cells, continuously producing FIV‐Pet, served as a model for chronic infection. Crandell Rees feline kidney (CRFK) cells were infected by either FIV‐Pet or feline adenovirus (FeAdV) as a model for transactivation and opportunistic viral infection. Cell cultures were treated pre‐ and post‐infection with serial dilutions of spray‐dried FWGE (Avemar pulvis, AP), a standardized active ingredient in commercial Avemar products. Residual FIV and FeAdV infectivity was quantified.ResultsIn a concentration‐dependent manner, AP inhibited replication of FIV strains in MBM and CRFK cells by 3–5 log. Low AP concentration prevented FIV‐Pet release from FL‐4 cells. Higher concentrations destroyed virus‐producing cells with cytopathic effects resembling apoptosis. AP strongly inhibited FeAdV production inside CRFK cells but not in HeLa cells. Adenovirus particles are then released via the disintegration of CRFK cells.DiscussionThis report is the first to describe the antiviral effects of Avemar. Further studies are required to confirm its in vitro and in vivo effects and to investigate the potential for its use as a nutraceutical in FIV‐infected felines or HIV‐infected humans.ConclusionAvemar, as a single nutraceutical, inhibits FIV replication and destroys retrovirus carrier cells. An important conclusion is that prolonged Avemar treatment might reduce the number of retrovirus‐producing cells in the host.
A ‘Bottom-Up’ Approach to Transcultural Identities: Petra and Women Detectives in Italian TV Crime Drama
Authors: D’Amelio Elena , Re Valentina 
Published: April 2023

AbstractIn her The TV Crime Drama, Turnbull (The TV Crime Drama. Edinburgh: Edinburgh University Press, 2014) argues that “the portrayal of women in the crime drama series has served as an index of women’s changing role in society while providing a catalyst for debate, both in the popular press and in the field of feminist media studies”. Moving from these premises, our aim is to analyse the Italian series Petra (Sky 2020–) within the larger context of contemporary European TV crime productions, to investigate the recurrences, similarities, and differences in the construction, representation, and consumption of TV female detectives, through a conceptualization of what has been called “mediated cultural encounters” (Bondebjerg et al. Transnational European Television Drama: Production, Genres and Audiences. Palgrave Macmillan, 2017). We consider Rosi Braidotti’s claim of the necessity of a “post nationalistic understanding of cultural identity” (2001) as a framework of analysis for the inter-related issues of gender, multiculturalism, and European identities.
Geometrical Analysis of a Brick Vault by Slices from the Aurelian Walls in Rome
Authors: Aliberti Licinia , de-Miguel-Sánchez Manuel , González-Uriel Ana 
Published: April 2023

AbstractThis work focuses on the analysis of a singular case of brick vault by slices from the Aurelian Walls in Rome. The study is based on an accurate survey carried out through automated photogrammetry. This analysis aims to determine the geometry of the vault and compare it with the theoretical model of its type.
On a singular limit as $$\theta \rightarrow 0$$ for a model for the evolution of morphogens in a growing tissue
Authors: Coclite G. M. , Coclite M. 
Published: April 2023

AbstractThis paper is devoted to the singular limit of a model for the regulation of growth and patterning in developing tissues by diffusing morphogens. The model is governed by a system of nonlinear PDEs. The arguments are based on energy estimates and a change of variable that reduces the system into a nonlinear PDE with singular diffusion.
Category $${\mathcal {O}}$$ for Takiff Lie algebras
Authors: Chaffe Matthew 
Published: April 2023

AbstractWe study category$${\mathcal {O}}$$Ofor Takiff Lie algebras$${\mathfrak {g}}\otimes {\mathbb {C}}[\epsilon ]/(\epsilon ^2)$$g⊗C[ϵ]/(ϵ2)where$${\mathfrak {g}}$$gis the Lie algebra of a reductive algebraic group over$${\mathbb {C}}$$C. We decompose this category as a direct sum of certain subcategories and use an analogue of parabolic induction functors and twisting functors for BGG category$${\mathcal {O}}$$Oto prove equivalences between these subcategories. We then use these equivalences to compute the composition multiplicities of the simple modules in the Verma modules in terms of composition multiplicities in the BGG category$${\mathcal {O}}$$Ofor reductive subalgebras of$${\mathfrak {g}}$$g. We conclude that the composition multiplicities are given in terms of the Kazhdan–Lusztig polynomials.
The 10th International Conference on cGMP 2022: recent trends in cGMP research and development—meeting report
Authors: Friebe Andreas , Kraehling Jan R. , Russwurm Michael , Sandner Peter , Schmidtko Achim 
Published: April 2023

AbstractIncreasing cGMP is a unique therapeutic principle, and drugs inhibiting cGMP-degrading enzymes or stimulating cGMP production are approved for the treatment of various diseases such as erectile dysfunction, coronary artery disease, pulmonary hypertension, chronic heart failure, irritable bowel syndrome, or achondroplasia. In addition, cGMP-increasing therapies are preclinically profiled or in clinical development for quite a broad set of additional indications, e.g., neurodegenerative diseases or different forms of dementias, bone formation disorders, underlining the pivotal role of cGMP signaling pathways. The fundamental understanding of the signaling mediated by nitric oxide-sensitive (soluble) guanylyl cyclase and membrane-associated receptor (particulate) guanylyl cyclase at the molecular and cellular levels, as well as in vivo, especially in disease models, is a key prerequisite to fully exploit treatment opportunities and potential risks that could be associated with an excessive increase in cGMP. Furthermore, human genetic data and the clinical effects of cGMP-increasing drugs allow back-translation into basic research to further learn about signaling and treatment opportunities. The biannual international cGMP conference, launched nearly 20 years ago, brings all these aspects together as an established and important forum for all topics from basic science to clinical research and pivotal clinical trials. This review summarizes the contributions to the “10th cGMP Conference on cGMP Generators, Effectors and Therapeutic Implications,” which was held in Augsburg in 2022 but will also provide an overview of recent key achievements and activities in the field of cGMP research.
Low-frequency variability enhancement of the midlatitude climate in an eddy-resolving coupled ocean–atmosphere model. Part I: anatomy
Authors: Kurashina Ryosuke , Berloff Pavel 
Published: April 2023

AbstractThis study investigated the coupling of the wind-driven ocean gyres with the atmospheric westerly jet using an idealised, eddy-resolving, coupled model. An empirical orthogonal function analysis of the low-pass filtered data showed that the ocean gyre variability is dominated by meridional shifts of the western boundary current extension (WBCE) and changes in the strength of the subtropical inertial recirculation zone. On the other hand, the atmospheric potential vorticity (PV) variability is dominated by the growth of standing Rossby wave patterns, while its pressure variability is dominated by a zonally-asymmetric meridional shift of the atmospheric jet. Damping sea surface temperature (SST) variability in the atmosphere was shown to weaken its PV variability and reduce the zonal asymmetry of the jet-shift mode. Singular value decompositions revealed a positive feedback between meridional shifts of the WBCE and the growth of standing Rossby wave disturbances in the atmospheric jet. The atmosphere’s response is controlled by shifts in the meridional eddy heat flux over the SST front which triggers the growth of baroclinic instabilities. This instability growth eventually leads to a large-scale, barotropic pressure response over the eastern ocean basin, or an aforementioned meridional shift of the atmospheric jet. Reduction in the atmospheric resolution inhibits the ability of atmospheric eddies to resolve length scales associated with meridional shifts of the SST front and WBCE. The lack of resolution consequently weakens the influence of ocean gyre variability on the atmospheric jet and reduces the strength of the positive feedback.
Efficacy and predictive factors of endoscopic ultrasound-guided ethanol ablation in benign solid pancreatic tumors
Authors: Choi Jin Ho , Paik Woo Hyun , Lee Sang Hyub , Lee Min Woo , Cho In Rae , Ryu Ji Kon , Kim Yong-Tae 
Published: April 2023

Abstract
Backgrounds and Objectives
Endoscopic ultrasound-guided ethanol ablation (EUS-EA) has recently been introduced for the management of solid pancreatic tumors, including pancreatic neuroendocrine tumors (PNETs) and solid pseudopapillary tumors (SPTs). The study aims to evaluate the efficacy and predictive factors for response of EUS-EA in solid pancreatic tumors.

Methods
Between October 2015 and July 2021, 72 patients who underwent EUS-EA for solid pancreatic tumors were included. The study outcomes were to evaluate the efficacy of EUS-EA with complete remission (CR) and objective response, and their predictive factors.

Results
During follow-up, 47 patients were diagnosed with PNETs and 25 with SPTs. Eight cases reached CR and 48 reached objective response. When compared with SPTs, PNETs showed similar duration to reach CR (median not reached; p = 0.319), but shorter duration to reach objective response (PNETs: median 20.6 months, 95%CI 10.26–30.88; SPTs: median 47.7 months, 95%CI 18.14–77.20; p = 0.018). Ethanol dosage > 0.35 ml/cm3 shortened the duration to reach CR (median not reached; p = 0.026) and objective response (median 42.5 months, 95%CI 25.34–59.66 vs. 19.6 months, 95%CI 10.17–29.09; p = 0.006). CR had no significant predictive factors, but PNETs showed significant predictive factors for objective response (HR 3.34, 95%CI 1.07–10.43; p = 0.038). Twenty-seven patients experienced adverse events, and there were two severe cases.

Conclusion
EUS-EA for pancreatic solid lesions seems feasible as a local treatment for patients who refuse or are unfit for surgery. Additionally, PNETs seem to be the better candidate for EUS-EA.
Co-creative art processes with cancer patients from the artists’ perspective: a qualitative study exploring resonance theory
Authors: Weeseman Yvonne , Scherer-Rath Michael , Christophe Nirav , Dörr Henny , Helmich Esther , Sprangers Mirjam A. G. , van Poecke Niels , van Laarhoven Hanneke W. M. 
Published: April 2023

AbstractPurposeCo-creation, characterised by artists and patients creating a joint work of art, may support patients with the integration of life events into their life story, such as living with cancer. In the process of co-creation, resonance relationships between patients, artists and material may evolve that support integration. We aim to investigate if and if so, how resonance relationships occur from the perspective of the artist.MethodsWe used the first 10 audio recordings of supervision sessions between eight artists and their two supervisors on ongoing co-creation processes with cancer patients. By conducting a qualitative template analysis in AtlasTi, we searched for the presence of resonance, as defined by its four main characteristics,Being affected, touched and moved;Self-efficacy and responding;Moments of uncontrollability; andAdaptive transformation. In addition, two case descriptions are presented.ResultsWe found resonance relationships to be present in the studied co-creation processes where moments of uncontrollability can lead to a next step in the process of co-creation and as such form an important factor within co-creation.ConclusionsThe current study suggests focus on elements of resonance relationships within co-creation, specifically practising with uncontrollability while working with art, could strengthen interventions targeting integration of life events in advanced cancer patients.
Effects of intravascular photobiomodulation on cognitive impairment and crossed cerebellar diaschisis in patients with traumatic brain injury: a longitudinal study
Authors: Lin Yen-Po , Ku Chih-Hung , Chang Cheng-Chiang , Chang Shin-Tsu 
Published: April 2023

Abstract
The association between intravascular photobiomodulation (iPBM) and crossed cerebellar diaschisis (CCD) and cognitive dysfunction in patients with traumatic brain injury (TBI) remains unknown. We postulate that iPBM might enable greater neurologic improvements. The objective of this study was to evaluate the clinical impact of iPBM on the prognosis of patients with TBI. In this longitudinal study, patients who were diagnosed with TBI were recruited. CCD was identified from brain perfusion images when the uptake difference of both cerebella was > 20%. Thus, two groups were identified: CCD( +) and CCD( −). All patients received general traditional physical therapy and three courses of iPBM (helium–neon laser illuminator, 632.8 nm). Treatment assemblies were conducted on weekdays for 2 consecutive weeks as a solitary treatment course. Three courses of iPBM were performed over 2–3 months, with 1–3 weeks of rest between each course. The outcomes were measured using the Rancho Los Amigos Levels of Cognitive Functioning (LCF) tool. The chi-square test was used to compare categorical variables. Generalized estimating equations were used to verify the associations of various effects between the two groups. p < 0.05 indicated a statistically significant difference. Thirty patients were included and classified into the CCD( +) and CCD( −) groups (n = 15, each group). Statistics showed that before iPBM, CCD in the CCD( +) group was 2.74 (exp 1.0081) times higher than that of CCD( −) group (p = 0.1632). After iPBM, the CCD was 0.64 (exp-0.4436) times lower in the CCD( +) group than in the CCD( −) group (p < 0.0001). Cognitive assessment revealed that, before iPBM, the CCD( +) group had a non-significantly 0.1030 lower LCF score than that of CCD( −) group (p = 0.1632). Similarly, the CCD( +) group had a non-significantly 0.0013 higher score than that of CCD( −) after iPBM treatment (p = 0.7041), indicating no significant differences between the CCD( +) or CCD( −) following iPBM and general physical therapy. CCD was less likely to appear in iPBM-treated patients. Additionally, iPBM was not associated with LCF score. Administration of iPBM could be applied in TBI patients to reduce the occurrence of CCD. The study failed to show differences in cognitive function after iPBM, which still serves as an alternative non-pharmacological intervention.
Building trust for sustainable access and benefit-sharing of biological control genetic resources: a CABI case study
Authors: Weyl Philip S. R. , Hinz Hariet L. , Rwomushana Ivan , Mulema Joseph , Diaz-Soltero Hilda , Smith David 
Published: April 2023

AbstractCABI is a not-for-profit international organization with the mission of improving people’s lives worldwide by solving problems in agriculture and the environment, while engendering trust and facilitating science. As an organisation CABI is both a provider and a user of biological control agents and regularly acting as an intermediary between provider and user countries. As a way of building trust between both sides, access and benefit sharing (ABS) policy and ABS best practices developed around the principles of the Nagoya protocol should be publicly accessible. CABI aims to facilitate compliance with national legislation on ABS through its best practices for the countries in which we work and those that we provide genetic resources. CABI adopted the position to share benefits whether the provider country is party to the Nagoya Protocol or not. We use a case study on the biological control of the coffee berry borer (Hypothenemus hampei (Ferrari)) to illustrate the implementation of ABS best practices for the overlap between biological control and ABS. In respect to Digital Sequence Information (DSI) associated with genetic resources CABI contributes to the ongoing global debate and evaluates how this may impact biocontrol research and delivery. The current view is that publishing sequence data is sharing descriptive information and thus delivers benefit-sharing from its generation. However, if DSI is used in a product placed on the market, there is justification for benefit sharing.
Fiscal Costs of Climate Policies: Role of Tax, Political, and Behavioural Distortions
Authors: van der Ploeg Frederick 
Published: April 2023

AbstractHere I review the fiscal costs of carbon pricing and climate policies, paying due attention to second-best as well as first-best polies. This starts with a discussion of when the double dividend hypothesis, i.e. when recycling carbon taxes via lower income taxes boosts employment and lowers the marginal cost of public funds. I propose that recycling carbon tax revenue benefits from considering the income on the whole distribution of households, since this allows one to get a better understanding of the political feasibility of carbon tax reforms. Political feasibility also requires intergenerational and international transfers to ensure all generations and countries benefit from carbon tax reform. The politics of carbon tax reform also requires one to take account of business cycle aspects, heightened salience of carbon taxes, and the propensity of policymakers to procrastinate and prefer subsidies to taxes.
The effect of grassland type and proximity to the city center on urban soil and vegetation coverage
Authors: Mollashahi Hassanali , Szymura Magdalena , Perera Peliyagodage Chathura Dineth , Szymura Tomasz H. 
Published: April 2023

AbstractUrban soils with associated vegetation are important components of urban ecosystems, providing multiple regulating and supporting ecosystem services. This study aimed to analyze the differences in the soil chemistry and vegetation of urban grasslands considering urbanization gradient and urban grassland type (UGT). We hypothesized that the chemical properties of soil, such as metal content, as well as vegetation traits, differ according to grassland type (lawns, grasslands in parks, grasslands on river embankments, and roadsides) and the location of grassland patches (city center versus peripheries). Our samples included 94 UGT patches which each patch represented by four square sampling plots sized 1 m2. The results showed high differentiation of measured traits unrelated to UGT and location. The exception was K content, with a relatively high concentration in lawns, and some metals (Cd, Cu, Pb, Zn), with higher concentrations in the city center than in the peripheries. We found two grassland patches located in the city center where the concentrations of Pb, Zn, and Cu exceeded the level authorized by Polish standards. In the case of vegetation traits, the variability was not structured considering the UGT and location of the patches, except for bare soil cover, which was higher in lawns in the city center compared to embankments in the peripheries. We observed correlations between vegetation traits and soil chemical properties. The vascular plant species richness decreased when N, P, and C content, along with an increase in grass cover and a decrease in herbs.
COVID-19 Vaccination Program for Undocumented Migrants: Notes from the Field of a Regional Center of General Medicine and Public Health, Canton of Vaud, Switzerland
Authors: Morisod Kevin , Nikles Justin , Miauton Alix , Maussang Laurence Bouche , Vermeulen Brigitte Pahud , Bodenmann Patrick 
Published: April 2023

AbstractThe COVID-19 pandemic highlighted health inequities for vulnerable populations and the need for more equitable care and access to vaccination. This article described the implementation of a COVID-19 vaccination program for undocumented migrants in a regional academic center of general medicine and public health (Unisanté). The vaccination program’s specific components included: triple coordination between the health authorities, the regional center and community partners, a walk-in and free service, no health insurance required, qualified nursing and administrative staff with previous experience with vulnerable populations, translated information materials and interpreters, a guarantee of confidentiality and a widespread communication campaign within the communities. In total, 2’351 undocumented migrants from 97 nationalities received at least one dose of mRNA COVID-19 vaccine (Spikevax) and 2242 were considered fully vaccinated. Although it was hard to assess its global effectiveness, the program vaccinated a significant number of undocumented adult migrants in the Canton of Vaud. The difficulties linked to the pandemic context, the heavy workload for healthcare staff and the limited resources were overcome by strong collaborations between the different actors involved throughout the program. Targeted public health policies, such as vaccination programs for undocumented migrants, are essential to guarantee equitable care, especially in pandemic times.