bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dedication to the craft: developing pre-service teachers into social justice advocates through PDS and poetry
Authors: Cormier Kerry 
Published: June 2023

PurposeThe purpose of this poetic inquiry was to understand how the professional development school (PDS) model can help pre-service teachers (PSTs) develop an inclusive philosophy of teaching while positioning themselves as social justice advocates. Four clinical interns collaborated in the research process guided by the university professor-in-residence (PIR).Design/methodology/approachTo conduct this poetic inquiry the interns kept journals, participated in individual interviews and weekly book club discussions to help us understand how education is situated within a broader social justice framework. Transcription poems were created from discussion and interview transcripts to capture the interns' perspectives and experiences in developing their philosophies.FindingsThe findings, shared through transcription poems, indicate that the interns established inclusive beliefs, experienced tensions between their beliefs and practices and emphasize the importance of community in developing as social justice advocates.Originality/valueBy sharing the findings through poetry, this study invites a more focused look into the nuances of PST’s emerging beliefs on inclusive education in a PDS.
Critical ontologies: rethinking relations to other‐than‐humans from the Bolivian Andes
Authors: Winchell Mareike 
Published: June 2023

AbstractDrawing from fieldwork and archival research carried out in Bolivia between 2010 and 2017, this article undertakes a rethinking of Indigenous ontologies in light of Bolivian interlocutors’ efforts to navigate deeply precarious ties to named places and saints. Attention to such instabilities challenges romantic accounts of ontology that presume a stable domain of materiality or religiosity outside of practice. During fieldwork in central Bolivia, I learned about the ways that Quechua farmers negotiated the relational and ecological effects of a divisive history of indentured labour and sexual violence through acts of devotion includingparaman purina(‘walking for rain’), feasting, flute‐play, dance, and chapel prayer each February for the Patron Saint La Virgen de la Candelaria, named places, and the Pachamama. These practices sought to rebuild ties to named places that were interrupted by the forbidding of offerings by the prior hacienda master and reshaped by state projects of Indigenous revivalism. These devotional practices, and participants’ narrations of them, offer insight into the political workings of Indigenous ontologies in twenty‐first‐century Bolivia. I proposecritical ontologiesas a scholarly lens that insists upon placing relations with other‐than‐humans within broader fields of legal and political contestation over rights, nature, and Indigeneity.
RETRACTED: Management of Impacted Fetal Head at Caesarean Birth
Authors: Cornthwaite Katie , Bahl Rachna , Winter Cathy , Wright Alison , Kingdom John , Walker Kate F. , Tydeman Graham , Briley Annette , Schmidt‐Hansen Mia , Draycott Tim ,   the Royal College of Obstetricians & Gynaecologists
Published: June 2023

Plain language summaryOver one‐quarter of women in the UK have a caesarean birth (CB). More than one in 20 of these births occurs near the end of labour, when the cervix is fully dilated (second stage). In these circumstances, and when labour has been prolonged, the baby’s head can become lodged deep in the maternal pelvis making it challenging to deliver the baby. During the caesarean birth, difficulty in delivery of the baby’s head may result – this emergency is known as impacted fetal head (IFH). These are technically challenging births that pose significant risks to both the woman and baby. Complications for the woman include tears in the womb, serious bleeding and longer hospital stay. Babies are at increased risk of injury including damage to the head and face, lack of oxygen to the brain, nerve damage, and in rare cases, the baby may die from these complications.Maternity staff are increasingly encountering IFH at CB, and reports of associated injuries have risen dramatically in recent years. The latest UK studies suggest that IFH may complicate as many as one in 10 unplanned CBs (1.5% of all births) and that two in 100 babies affected by IFH die or are seriously injured. Moreover, there has been a sharp increase in reports of babies having brain injuries when their birth was complicated by IFH.When an IFH occurs, the maternity team can use different approaches to help deliver the baby’s head at CB. These include: an assistant (another obstetrician or midwife) pushing the head up from the vagina; delivering the baby feet first; using a specially designed inflatable balloon device to elevate the baby’s head and/or giving the mother a medicine to relax the womb. However, there is currently no consensus for how best to manage these births. This has resulted in a lack of confidence among maternity staff, variable practice and potentially avoidable harm in some circumstances.This paper reviews the current evidence regarding the prediction, prevention and management of IFH at CB, integrating findings from a systematic review commissioned from the National Guideline Alliance.
Why intrauterine device (IUD) utilization is low in southwestern Ethiopia. A mixed‐method study
Authors: Amenu Demisew , Wakjira Tekle , Tadele Afework , Kebede Alemi , Asefa Zerihun 
Published: June 2023

AbstractIntroductionAn intrauterine device (IUD) is a highly effective long‐acting and reversible contraceptive method widely available around the world. However, only a small proportion of women in developing countries, including Ethiopia, are currently using the method. Therefore, this study aimed to identify why IUD utilization is low in southwestern Ethiopia.Material and methodsA mixed‐method study involving health facilities and communities was conducted. The focus group discussions and key informant interviewees for the qualitative study were selected purposively, whereas 844 women family planning users were selected using systematic random sampling from November 1–30, 2020. Quantitative data was collected using Open Data Kit and analyzed using Stata version 16.0. Multivariable logistic regression analyses were done to identify significant factors influencing IUD use. The qualitative data were tape‐recorded, transcribed, and finally, thematic analyses were done.ResultsA total of 784 participants were involved in the study yielding a response rate of 92.9%. Among all respondents, only 1.3%, 2.4%, and 30.0% had been using an IUD, preferred an IUD, and had the intention to use an IUD, respectively. The main reported barriers to use an IUD among qualitative participants were fear of side‐effects, religious prohibitions of contraception use, husband disapproval, lack of training by health workers, misconceptions, and longer duration of use. IUD information (AOR = 2.19 [CI: 1.56–3.08]), and rich wealth status (AOR = 1.70 [CI: 1.13–2.56]) were associated with the intention to continue or start to use an IUD.ConclusionsIUD use and information on IUDs in the study area was very low. Information about IUDs, wealth status, and partner disapproval were determinant factors for intention to use an IUD. Thus, a regular awareness creation program using accessible media platforms by the government and stakeholders on IUD use is necessary to provide reliable information to the community and resolve misconceptions. In addition, women's empowerment to balance partner dominance on decision‐making of contraception use and health care worker training on long‐acting reversible contraceptives (LARCs) to increase access to LARC services are necessary to increase uptake of LARCs in general and of IUDs, in particular in the study regions.
Les géographes du Québec et la question professionnelle : essai d'interprétation sociohistorique, 1945–2000
Authors: Pelletier Raphaël 
Published: June 2023

RésuméL'étude de l'histoire contemporaine de la géographie au prisme de la sociologie des professions permet de s'intéresser aux « trajectoires professionnelles », et ce, à titre d'objets. Par l'analyse de documents d'archives, trois périodes ont pu être établies, montrant ainsi les particularités contextuelles des débats entourant la présence des géographes dans le milieu professionnel. De 1945 à 1962, on observe la tripartition graduelle de la géographie dans trois catégories d'espaces sociaux distincts, soit les écoles, l'université et le milieu professionnel. De 1963 à 1978, on constate la naissance et le déclin d'un projet collectif équivoque, à savoir celui de la création d'une corporation des géographes du Québec. De 1979 à la fin du 20esiècle, on remarque une valorisation de l'Association des géographes du Québec (AGQ), devenue l'Association professionnelle des géographes du Québec (APGQ) en 1985, à titre de lieu de représentation démocratique et de défense des intérêts professionnels des géographes.
WDR54 exerts oncogenic roles in T‐cell acute lymphoblastic leukemia
Authors: Li Huan , Zhang Danlan , Fu Qiuxia , Wang Shang , Zhang Xin , Lin Zhixian , Wang Zhongyuan , Song Jiaxing , Su Zijie , Xue VivianWeiwen , Liu Shanshan , Chen Yun , Zhou Liang , Zhao Na , Lu Desheng 
Published: June 2023

AbstractWDR54 has been recently identified as a novel oncogene in colorectal and bladder cancers. However, the expression and function of WDR54 in T‐cell acute lymphoblastic leukemia (T‐ALL) were not reported. In this study, we investigated the expression of WDR54 in T‐ALL, as well as its function in T‐ALL pathogenesis using cell lines and T‐ALL xenograft. Bioinformatics analysis indicated high mRNA expression of WDR54 in T‐ALL. We further confirmed that the expression of WDR54 was significantly elevated in T‐ALL. Depletion of WDR54 dramatically inhibited cell viability and induced apoptosis and cell cycle arrest at S phase in T‐ALL cells in vitro. Moreover, knockdown of WDR54 impeded the process of leukemogenesis in a Jurkat xenograft model in vivo. Mechanistically, the expression of PDPK1, phospho‐AKT (p‐AKT), total AKT, phospho‐ERK (p‐ERK), Bcl‐2 and Bcl‐xL were downregulated, while cleaved caspase‐3 and cleaved caspase‐9 were upregulated in T‐ALL cells with WDR54 knockdown. Additionally, RNA‐seq analysis indicated that WDR54 might regulate the expression of some oncogenic genes involved in multiple signaling pathways. Taken together, these findings suggest that WDR54 may be involved in the pathogenesis of T‐ALL and serve as a potential therapeutic target for the treatment of T‐ALL.
FABP5 regulates lipid metabolism to facilitate pancreatic neuroendocrine neoplasms progression via FASN mediated Wnt/β‐catenin pathway
Authors: Lu Feiyu , Ye Mujie , Hu Chunhua , Chen Jinhao , Yan Lijun , Gu Danyang , Xu Lin , Tian Ye , Bai Jianan , Tang Qiyun 
Published: June 2023

AbstractPancreatic neuroendocrine neoplasms (pNENs) are among the most frequently occurring neuroendocrine neoplasms (NENs) and require targeted therapy. High levels of fatty acid binding protein 5 (FABP5) are involved in tumor progression, but its role in pNENs remains unclear. We investigated the mRNA and protein levels of FABP5 in pNEN tissues and cell lines and found them to be upregulated. We evaluated changes in cell proliferation using CCK‐8, colony formation, and 5‐ethynyl‐2′‐deoxyuridine assays and examined the effects on cell migration and invasion using transwell assays. We found that knockdown of FABP5 suppressed the proliferation, migration, and invasion of pNEN cell lines, while overexpression of FABP5 had the opposite effect. Co‐immunoprecipitation experiments were performed to clarify the interaction between FABP5 and fatty acid synthase (FASN). We further showed that FABP5 regulates the expression of FASN via the ubiquitin proteasome pathway and both proteins facilitate the progression of pNENs. Our study demonstrated that FABP5 acts as an oncogene by promoting lipid droplet deposition and activating the WNT/β‐catenin signaling pathway. Moreover, the carcinogenic effects of FABP5 can be reversed by orlistat, providing a novel therapeutic intervention option.
Regional anesthesia for transplantation surgery – A white paper part 1: Thoracic transplantation surgery
Authors: Ander Michael , Mugve Neal , Crouch Cara , Kassel Cale , Fukazawa Kyota , Izaak Robert , Deshpande Ranjit , McLendon Charles , Huang Jiapeng 
Published: June 2023

AbstractTransplantation surgery continues to evolve and improve through advancements in transplant technique and technology. With the increased availability of ultrasound machines as well as the continued development of enhanced recovery after surgery (ERAS) protocols, regional anesthesia has become an essential component of providing analgesia and minimizing opioid use perioperatively. Many centers currently utilize peripheral and neuraxial blocks during transplantation surgery, but these techniques are far from standardized practices. The utilization of these procedures is often dependent on transplantation centers’ historical methods and perioperative cultures. To date, no formal guidelines or recommendations exist which address the use of regional anesthesia in transplantation surgery. In response, the Society for the Advancement of Transplant Anesthesia (SATA) identified experts in both transplantation surgery and regional anesthesia to review available literature concerning these topics. The goal of this task force was to provide an overview of these publications to help guide transplantation anesthesiologists in utilizing regional anesthesia. The literature search encompassed most transplantation surgeries currently performed and the multitude of associated regional anesthetic techniques. Outcomes analyzed included analgesic effectiveness of the blocks, reduction in other analgesic modalities—particularly opioid use, improvement in patient hemodynamics, as well as associated complications. The findings summarized in this systemic review support the use of regional anesthesia for postoperative pain control after transplantation surgeries. Part 1 of the manuscript focuses on regional anesthesia performed in thoracic transplantation surgeries, and part 2 in abdominal transplantations.
Mortality and neurodevelopmental outcome after invasive group B streptococcal infection in infants
Authors: Mynarek Maren , Vik Torstein , Andersen Guro L. , Brigtsen Anne K. , Hollung Sandra Julsen , Larose Tricia L. , Lydersen Stian , Olsen Lene C. , Strøm Marianne S. , Afset Jan E. 
Published: June 2023

AbstractAimTo assess case fatality rate (CFR), infant mortality, and long‐term neurodevelopmental disorders (NDDs) after invasive group B streptococcal (GBS; Streptococcus agalactiae) infection in infants.MethodChildren born in Norway between 1996 and 2019 were included. Data on pregnancies/deliveries, GBS infection, NDDs, and causes of death were retrieved from five national registries. The exposure was culture‐confirmed invasive GBS infection during infancy. Outcomes were mortality and NDDs, the latter at a mean age of 12 years 10 months.ResultsAmong 1 415 625 live‐born children, 866 (87%) of 1007 infants diagnosed with GBS infection (prevalence 0.71 per 1000) were included. The CFR was 5.0% (n = 43). GBS infection was associated with higher infant mortality (relative risk 19.41; 95% confidence interval [CI] 14.79–25.36) than the general population. Among survivors, 169 (20.7%) children were diagnosed with any NDD (relative risk 3.49; 95% CI 3.05–3.98). In particular, GBS meningitis was associated with high risks of attention‐deficit/hyperactivity disorder, cerebral palsy, epilepsy, hearing impairment, and pervasive and specific developmental disorder.InterpretationThe burden of invasive GBS infection during infancy is considerable and continues to affect children beyond infancy. These findings emphasize the need for new preventive strategies for disease reduction, and the need for survivors to be directly included into early detection pathways to access early intervention if required.What this paper adds

The burden of invasive group B streptococcal (GBS) infection in Norway is considerable.
Of GBS infection survivors, 20.7% were diagnosed with neurodevelopmental disorders (NDDs) at mean age 12 years 10 months.
Infants with GBS meningitis were more often diagnosed with NDDs.
Absolute risks associated with GBS infections were highest for pervasive and specific developmental disorder, cerebral palsy, and attention‐deficit/hyperactivity disorder.
Is diabetic retinopathy screening worthwhile among people first diagnosed with diabetes at older ages? A cohort study of Norfolk diabetic retinopathy screening programme
Authors: Brodie James , Misra Aseema , Jones Colin D. , Jenkins Christel , Bachmann Max O. 
Published: June 2023

AbstractAimsEngland's Diabetic Eye Disease Screening Programme offers screening to every resident over age 12 with diabetes, starting as soon as possible after diagnosis and repeated annually. People first diagnosed with diabetes at older ages have shorter life expectancy and therefore may be less likely to benefit from screening and treatment. To inform decisions about whether diabetic eye screening policy should be stratified by age, we investigated the probability of receiving treatment according to age at first screening episode.MethodsThis was a cohort study of participants in the Norfolk Diabetic Retinopathy Screening Programme from 2006 to 2017, with individuals' programme data linked to hospital treatment and death data recorded up to 2021. We estimated and compared the probability, annual incidence and screening costs of receiving retinal laser photocoagulation or intravitreal injection and of death, in age groups defined by age at first screening episode.ResultsThe probability of death increased with increasing age at diagnosis, while the probability of receiving either treatment decreased with increasing age. The estimated cost of screening per person who received either or both treatments was £18,608 among all participants, increasing with age up to £21,721 in those aged 70–79 and £26,214 in those aged 80–89.ConclusionsDiabetic retinopathy screening is less effective and less cost‐effective with increasing age at diagnosis of diabetes, because of the increasing probability of death before participants develop sight‐threatening diabetic retinopathy and can benefit from treatment. Upper age limits on entry into screening programmes or risk stratification in older age groups may, therefore, be justifiable.
Managerial turnover in primary care clinics
Authors: Cole Samuel , Altindag Duha T. 
Published: June 2023

AbstractWe investigate the relationship between primary care clinic performance and managerial turnover. Results show that profit in a year is a strong indicator of whether the administrator will keep their job in the next year, although the clinics are certified as non‐profits. The effect is asymmetric. Positive profits contribute more to an administrator's chance of keeping their job than negative profits reduce it. In an extension analysis, we provide evidence that suggests new clinic managers improve their community's health by increasing access to their clinics and improving the quality of healthcare provision.
Do local expenditures on sports facilities affect sports participation?
Authors: Steckenleiter Carina , Lechner Michael , Pawlowski Tim , Schüttoff Ute 
Published: June 2023

AbstractThis paper contributes to the literature evaluating the performance of local governments by analyzing the effect of local public expenditures on sports facilities on sports participation in Germany. To this end, we use a new data base containing public expenditures at the municipality level and link this information with individual level data. We form locally weighted averages of expenditures based on geographic distances and analyze how effects of sports facility expenditures change with different expenditures levels (“dose‐response relationship”). We find no effect of sports facility expenditures on individual sports participation. These findings are robust across age groups and municipality sizes.
Mutualisms in a warming world
Authors: Cruz Austin R. , Davidowitz Goggy , Moore Christopher M. , Bronstein Judith L. 
Published: June 2023

AbstractPredicting the impacts of global warming on mutualisms poses a significant challenge given the functional and life history differences that usually exist among interacting species. However, this is a critical endeavour since virtually all species on Earth depend on other species for survival and/or reproduction. The field of thermal ecology can provide physiological and mechanistic insights, as well as quantitative tools, for addressing this challenge. Here, we develop a conceptual and quantitative framework that connects thermal physiology to species' traits, species' traits to interacting mutualists' traits and interacting traits to the mutualism. We first identify the functioning of reciprocal mutualism‐relevant traits in diverse systems as the key temperature‐dependent mechanisms driving the interaction. We then develop metrics that measure the thermal performance of interacting mutualists' traits and that approximate the thermal performance of the mutualism itself. This integrated approach allows us to additionally examine how warming might interact with resource/nutrient availability and affect mutualistic species' associations across space and time. We offer this framework as a synthesis of convergent and critical issues in mutualism science in a changing world, and as a baseline to which other ecological complexities and scales might be added.
Risk of a first clinical diagnosis of central nervous system demyelination in relation to human herpesviruses in the context of Epstein–Barr virus
Authors: Lucas Robyn M. , Lay Meav‐Lang J. , Grant James , Cherbuin Nicolas , Toi Cheryl S. , Dear Keith , Taylor Bruce V. , Dwyer Dominic E. ,   Ausimmune Investigator Group, Ponsonby Anne‐Louise 
Published: June 2023

AbstractBackground and purposeEpstein–Barr virus (EBV) is implicated in multiple sclerosis (MS) risk; evidence for other herpesviruses is inconsistent. Here, we test blood markers of infection with human herpesvirus 6 (HHV‐6), varicella zoster virus (VZV), and cytomegalovirus (CMV) as risk factors for a first clinical diagnosis of central nervous system demyelination (FCD) in the context of markers of EBV infection.MethodsIn the Ausimmune case–control study, cases had an FCD, and population controls were matched on age, sex, and study region. We quantified HHV‐6‐ and VZV‐DNA load in whole blood and HHV‐6, VZV, and CMV antibodies in serum. Conditional logistic regression tested associations with FCD risk, adjusting for Epstein–Barr nuclear antigen (EBNA) IgG, EBV‐DNA load, and other covariates.ResultsIn 204 FCD cases and 215 matched controls, only HHV‐6‐DNA load (positive vs. negative) was associated with FCD risk (adjusted odds ratio = 2.20, 95% confidence interval = 1.08–4.46, p = 0.03). Only EBNA IgG and HHV‐6‐DNA positivity were retained in a predictive model of FCD risk; the combination had a stronger association than either alone. CMV‐specific IgG concentration modified the association between an MS risk‐related human leucocyte antigen gene and FCD risk. Six cases and one control had very high HHV‐6‐DNA load (>1.0 × 106 copies/mL).ConclusionsHHV‐6‐DNA positivity and high load (possibly due to inherited HHV‐6 chromosomal integration) were associated with increased FCD risk, particularly in association with markers of EBV infection. With growing interest in prevention/management of MS through EBV‐related pathways, there should be additional consideration of the role of HHV‐6 infection.