bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hantavirus Pulmonary Syndrome: 1993–2018
Authors: Thorp Lauren , Fullerton Lynne , Whitesell Amy , Dehority Walter 
Published: March 2023

OBJECTIVESFrom 1993 to 2018, hantavirus infections were reported in 39 states, with hantavirus pulmonary syndrome (HPS) as the most common and fatal manifestation. To identify differences in the presentation of HPS between children and adults, we hypothesized that children with HPS would be diagnosed later in their illness course given the nonspecific clinical features of HPS.METHODSThis was an evaluation of the clinical and demographic characteristics of national HPS cases from 1993 to 2018. Data were from the Centers for Disease Control and Prevention database and 1 state department of health, comprising 97% of US cases. We compared children (0 to 12 years), adolescents (13 to 18 years), and adults using nonparametric and parametric analyses, with additional exploratory analyses to identify clinical variables associated with mortality.RESULTSAmong 719 HPS patients, 22 (3.0%) were aged ≤12 years, 47 (6.5%) were 13 to 18 years old, and the remaining 650 (90.4%) were adults. Overall mortality was 35.4% and did not differ between age groups (P = .8). The time between symptom onset and death differed by age group, with children living a median of 2 days (interquartile range [IQR] 2 to 3), adolescents 4 days (IQR 3 to 5), and adults 5 days (IQR 4 to 8; P = .001). The mean highest hematocrit and median highest creatinine level were significantly associated with mortality in those 0 to 18 years old but not adults.CONCLUSIONSIn our dataset representing the largest study of HPS in the United States, we found that children with HPS died more quickly than adults and that highest hematocrit and creatinine levels were associated with death only among those &lt;19 years old.
Physical recreation in the structure of students' active recreation
Authors: Zaytzev Viachesla , Prusik Krzysztof , Iermakov Sergii 
Published: March 2023

Background and Study Aim. The aim of the study is to generalize approaches to the concepts of physical recreation and recreational activities; reveal the directions and factors that contribute to the implementation of physical recreation; show the main provisions, means, forms, methods of physical recreation and its pedagogical principles.
Materials and Methods. Sources of information are publications in domestic literature. A total of 26 publications were identified.
Results. The article summarizes the experience of the authors on the problem of "Physical recreation": the concept, means, forms and methods of physical culture used in physical recreation. The basics of physical recreation of students are presented. These include: building a comprehensive program, developing valeological and recreational activities; joint creative activity of teachers and students; use of modern methods of health-forming technologies.
Conclusions. Favorable and unfavorable social factors should be taken into account in the process of motor activity formation. In practical work, the following areas should be taken into account: hygienic, health-improving and recreational, general preparatory and medical.
Methods of studying the cardiovascular system in students of a sports university in the process of recreational rest
Authors: Zaytzev Viacheslav , Iermakov Sergii , Gorner Karol , Prusik Krzysztof 
Published: March 2023

Background and Study Aim. The aim of the study is to develop a methodology for examining the cardiovascular system in students with different levels of physical activity.
Materials and Methods. Students of the Academy of Physical Culture (Kharkiv, Ukraine) took part in the study: 3-4 year full-time and part-time students. A scheme for examining the cardiovascular system in this category of students has been drawn up. A survey was conducted during practical exercises on physical recreation during the years 2006 – 2011. The research methods were taken as the basis: circulatory organs; patients with diseases of the cardiovascular system; circulatory systems.
Results. The definitions of recreation are considered. Its types and functions are shown. Directions for assessing the level of the functional state of the cardiovascular system in students with a high level of physical activity are given. A plan-scheme for studying this system has been drawn up. The peculiarity of the system is to take into account the specifics of the future profession. Assessment of the functional state of the student's cardiovascular system is carried out in a complex manner.
Conclusions. It is necessary to take into account the anamnesis of the entire life of the student. It is necessary to apply sports, clinical, instrumental, laboratory, biochemical research methods. The results of functional trials and tests should be taken into account. Functional tests and tests should reflect the response of the cardiovascular system to the physical load and determine the overall physical performance.
Developing a Comprehensive Physical Education Curriculum in Secondary Schools: Identifying and Exploring the Key Components of Content
Authors: Vaskov Yurij 
Published: March 2023

Background and study aim. This study aims to develop and theoretically justify the content of physical education in general educational institutions, particularly in secondary schools, based on the didactic model of the subject "Physical Culture".
Methodology. A systematic review of relevant literature was conducted using publications from the Vernadskyi National Library and sources in the Google search system. Keywords were used for the search in accordance with the topic of the study, and 26 sources were selected for analysis.
Results. The results of the study reveal that the content of physical education is based on a four-component composition, and a didactic model of the educational subject "Physical Culture" was developed. The model consists of two blocks: main or substantive and procedural, and the composition of each block is specified. The first block includes a theoretical component, methods of activity of an intellectual and practical nature, while the second block includes teaching methods, organizational forms of teaching, and teaching aids. The study clarifies the main components of theoretical knowledge and methods of intellectual and practical activities in physical education, as well as the functions of each component of the content of physical education.
Conclusions. The findings of this study contribute to the development of physical education in general educational institutions, particularly in secondary schools, by providing a comprehensive framework for designing an effective physical education curriculum.
Clinical Case of X-Linked Lymphoproliferative Syndrome Burdened with Hemophagocytic Lymphohistiocytosis and Crohn's Disease
Authors: Matros Ekaterina S. , Karitskaya Alena I. 
Published: March 2023

Background. X-linked lymphoproliferative (XLP) syndrome is hereditary disease with the incidence of 1-3 per 1 million born boys. This clinical case demonstrates a rare picture of XLP type 2 manifestation without prior Epstein-Barr virus.Clinical case description. Boy D., 15 years old, was admitted to Morozovskaya Children's City Hospital with complaints on fever, abdominal pain, loose stools, weight loss. The past medical history included hemophagocytic syndrome (remission) and acute erythema nodosum. We have performed several studies: abdominal ultrasound (hepatomegaly, dynamic changes in the intestine: parts of the small intestine were enlarged and walls were thickened, mass peristalsis, walls of transverse colon and descending colon are thickened up to 5 mm, mesenteric lymphadenopathy), rectosigmoidoscopy (high-activity ulcerative proctosigmoiditis corresponds to Crohn's disease), biochemical and clinical blood tests (active hemophagocytic syndrome), coagulogram (secondary hypocoagulation), myelogram (no data on hemoblastosis or aplastic condition). Virological blood tests (CMV, EBV, HHV-VI): negative. Laboratory and instrumental tests have revealed recurrence of hemophagocytic syndrome and Crohn's disease. The child was consulted by rheumatologist, hematologist, gastroenterologist, geneticist, neurologist, and clinical pharmacologist. The primary immune deficiency disease was suspected in this patient due to his medical history. Molecular genetic study was performed (deletion including the XIAP gene was revealed) and the diagnosis of primary immune deficiency was verified: X-linked lymphoproliferative syndrome type 2. Thus, allogeneic haematopoietic stem cell transplantation (HSCT) was performed.Conclusion. XLP diagnosis and management require multidisciplinary approach. The early diagnosis is crucial due to the high risk of secondary complications development that can significantly worsen the disease's prognosis. Allogeneic HSCT is the only effective treatment for the disease.
Protective Role of Vaccination against Tuberculosis and Hepatitis B in Prevention of Atopic Dermatitis: Report on Intermediate Results of Prospective Cohort Study
Authors: Petrova Veronika A. , Namazova-Baranova Leyla S. , Fedoseenko Marina V. , Rusinova Dina S. 
Published: March 2023

Background. Studies have shown that vaccination in the first hours/days after birth shifts the immune response from intrauterine Th2 towards Th1-type activation and reduces the risk of atopic conditions. However, we did not find published data from prospective studies on this topic.Objective. The aim of the study is to define the presence of negative correlation between vaccination against tuberculosis and hepatitis B in the first hours/days of life and atopic dermatitis development in infants.Methods. Continuous prospective study of children cohort born from April to June 2021 and observed in one outpatient’s clinic was carried out. Data from 307 infant’s records (F. 112/y), vaccination record cards (F. 063/y), prenatal and delivery records (F. 113/y-20, section № 3), and neonatal discharge summaries were analyzed for the decreed period. The child vaccination status (by the time of vaccination against tuberculosis and hepatitis B), presence of risk factors for allergic disease development, and presence of atopic dermatitis were evaluated.Results. Atopic dermatitis (AD) was significantly less likely to be diagnosed by the age of 1 year in infants from the group of BCG-M vaccinated at maternity hospital than in those vaccinated later or not vaccinated at all (15.2% versus 66% and 35.7%, respectively; p < 0,01). AD was less likely to develop in children with risk factors for allergic disease who were vaccinated against tuberculosis in the maternity hospital than in those vaccinated later or unvaccinated at all (18, 75 and 62.5%, respectively; p < 0.01). The ratio of children with diagnosed AD by the age of 12 months was significantly less in the group of children vaccinated against hepatitis B in the maternity hospital than in those vaccinated later or unvaccinated at all (17.6, 44.9 and 31.8%, respectively; p < 0.01). These ratios for children with risk of allergic disease development were 24%, 50% and 44.4%, respectively (p = 0.043). It has also been shown that timely vaccination with both vaccines in the early neonatal period significantly reduces the risk of AD in general infant population compared to non-vaccinated individuals or those who had only one vaccine (odds ratio [OR] 0.374; 95% confidence interval [CI] 0.253-0.552; p < 0.01). Whereas the disease development in children with allergic risk is less likely with timely vaccination (20.8% versus 53.3%; OR = 0.252; 95% CI 0.145–0.440; OR = 0.374; 95% CI 0,253–0,552; p < 0,01).Conclusion. The obtained results may indicate possible risk reduction for AD development due to timely preventive vaccination against tuberculosis and hepatitis B, especially in children with allergic risk. The study is currently ongoing.
Transient deficiency of protein S after past infection process, complications and outcome: clinical case
Authors: Gordeeva Olga B. , Dobrotok Albina V. , Selimzianova Liliia R. , Deeva Valeria A. 
Published: March 2023

Background. Purpura fulminans (PF) – is an acute rapidly progressive thrombosis of small-diameter blood vessels located mainly on the skin of the extremities. PF is characterized by high mortality rates. Patients can have serious consequences, including amputations and loss of fingers, foots or even extremities in general.Clinical case description. A clinical case of developing transient deficiency of protein S complicated by idiopathic PF on the 7th day after acute otitis in a 3-year-old boy due to past infection is presented. The progression of the disease developed within a few hours. The patient became hemorrhagic elements on the skin of extremities, and later — tissue necrosis. The conducted therapy facilitated to stop the pathological process in the form of PF, and also prevented the development of severe disabling complications in the child.Conclusion. Differential diagnosis and treatment should be fast and accurate, as the development of PF occurs in mere hours. Diagnostics should include expanded panel of coagulological tests and instrumental examinations, which determines the justifiability of a multidisciplinary approach in the patient management with disorders in the hemostatic system.
Pengaruh Kesesuaian Kompensasi, Sistem Informasi Akuntansi dan Keefektifan Pengendalian Internal Terhadap Kecenderungan Kecurangan Akuntansi
Authors: Sunaryo Karsam 
Published: March 2023

Abstract. The purpose of this research is to examine the role suitability of compensation, accounting information systems and the effectiveness of internal controls in accounting fraud tendencies. The population used in this research were employees of 3 Bank Companies. Questionnaires were used to collect data from respondents. Questionnaires were distributed to 44 employees of Bank Companies which were chosen by purposive sampling method. Single linear regression and multiple linear regression were used as a method to test the hypothesis in this research. The results of the study show that partially the suitability of compensation, accounting information systems and the effectiveness of internal controls have a significant positive effect on accounting fraud tendencies. In addition, the suitability of compensation, accounting information systems and the effectiveness of internal controls simultaneously influence the tendency of accounting fraud.Keywords. suitability of compensation, accounting information systems, effectiveness of internal controls and accounting fraud tendencies.Abstrak. Penelitian ini bertujuan untuk mengetahui pengaruh kesesuaian kompensasi, sistem informasi akuntansi dan efektifitas pengendalian internal terhadap kecenderungan kecurangan akuntansi. Populasi penelitian ini adalah sektor perbankan di Indonesia dan sampel yang dipilih adalah 3 perusahaan perbankan yang berlokasi di Jakarta dan Tangerang Selatan dengan unit analisis karyawan yang bekerja pada 3 perusahaan sektor perbankan. Pengumpulan data dilakukan dengan cara memberikan kuesioner kepada responden, yang berjumlah 44 karyawan pada bagian yang terkait dengan akuntansi. Uji hipotesis dilakukan dengan menggunakan metode regresi linier. Hasil penelitian menunjukkan bahwa secara parsial kesesuaian kompensasi, sistem informasi akuntansi dan efektifitas pengendalian internal berpengaruh signifikan positif terhadap kecenderungan kecurangan akuntansi. Selain itu, kesesuaian kompensasi, sistem informasi akuntansi dan efektifitas pengendalian internal secara simultan berpengaruh terhadap kecenderungan kecurangan akuntansi.Kata kunci. Kesesuaian Kompensasi, Sistem Informasi Akuntansi, Efektifitas Pengendalian Internal dan kecenderungan kecurangan akuntansi
Pengaruh Biaya Produksi, Debt to equity ratio, dan Perputaran Persediaan Terhadap Profitabilitas
Authors: Ramadita Elke Sonia , Suzan Leny 
Published: March 2023

Abstract. This study aims to investigate the factors that influence profitability among them production costs, debt to equity ratio and inventory turnover on the basic industrial and chemical manufacturing companies listed on the Indonesia Stock Exchange for the period 2014-2017. The sampling technique used is perposive sampling and obtained 26 firms with a research period of 4 years, this obtaining 104 sampel data. The method of data analysis in this study is panel data regression analysis using software eviews 9. The result showed that simultaneous production cost, DER and inventory turnover have a significant effect on profitability. While partially production costs and DER has a negative significant effect on profitability and inventory turnover has no effect on profitability.Keywords. Debt to equity ratio; Inventory turnover; Production cost; Profitability.Abstrak. Penelitian ini bertujuan untuk menginvestigasi faktor-faktor yang mempengaruhi profitabilitas perusahaan diantaranya biaya produksi, debt to equity ratio dan perputaran persediaan pada perusahaan manufaktur sektor industri dasar dan kimia yang terdaftar di Bursa Efek Indonesia periode 2014-2017. Teknik pengambilan sampel yang digunakan yaitu purposive sampling dan diperoleh 26 perusahaan dengan periode penelitian selama 4 tahun, sehingga diperoleh 104 data sampel. Metode analisis data dalam penelitian ini adalah analisis regresi data panel dengan menggunakan software eviews 9. Hasil penelitian menunjukkan secara simultan biaya produksi, DER dan perputaran persediaan berpengaruh signifikan terhadap profitabilitas. Sedangkan secara parsial biaya produksi dan DER berpengaruh negatif signifikan dan perputaran persediaan tidak berpengaruh terhadap profitabilitas.Kata kunci. Biaya produksi; Debt to equity ratio; Perputaran persediaan; Profitabilitas.
Pengaruh Leverage, Pergantian Manajemen, dan Audit Fee Terhadap Auditor Switching
Authors: Adli Syarifah Nadya , Suryani Elly 
Published: March 2023

Abstract. The purpose of this study is to investigate the effect of partial or simultaneous leverage variables, management changes, and audit fees on auditor switching on mining companies listed on the Indonesia Stock Exchange (IDX) for the 2013-2017 period. The population chosen in this study is a mining company listed on the Indonesia Stock Exchange (IDX) for the period 2013-2017. The method used for sampling in this study is to use purposive sampling technique, there are 10 companies that are research samples with a period of 5 years to obtain 50 observation data. Analysis of the data used is logistic regression analysis using SPSS 24 software. The results of this study prove that simultaneously leverage, management change, and audit fee have an effect on auditor switching. Partially, the leverage variable and management turnover have no effect on auditor switching, while the audit fee variable has a negative effect on the auditor switching.Keywords. auditor switching; leverage; management change; audit fee Abstrak. Tujuan dari penelitian ini yaitu menginvestigasi pengaruh secara parsial maupun simultan variabel leverage, pergantian manajemen, dan audit fee terhadap auditor switching pada perusahaan pertambangan yang terdaftar di Bursa Efek Indonesia (BEI) Periode 2013-2017. Adapun populasi yang dipilih dalam penelitian ini adalah perusahaan pertambangan yang terdaftar pada Bursa Efek Indonesia (BEI) periode 2013-2017. Metode yang digunakan untuk pngambilan sampel dalam penelitian ini yaitu menggunakan Teknik purposive sampling, terdapat 10 perusahaan yang menjadi sampel penelitian dengan kurun waktu 5 tahun sehingga diperoleh 50 data observasi. Analisis data yang digunakan adalah analisis regresi logistik dengan menggunakan software SPSS 24. Hasil penelitian ini membuktikan secara simultan leverage, pergantian manajemen, dan audit fee bersama-sama berpengaruh terhadap auditor switching, Secara parsial, variable leverage dan pergantian manajemen tidak berpengaruh terhadap auditor switching, sedangkan variabel audit fee berpengaruh dengan arah negatif terhadap auditor switching.Kata Kunci. auditor switching; leverage; pergantian manajemen; audit fee
Sustainability Reporting : Analisis Kinerja Keuangan dan Nilai Perusahaan
Authors: Anna Yane Devi , Dwi R.T Dita Rari 
Published: March 2023

Abstract. As more companies in Indonesia publish sustainability reports, the trend of research on the relationship between sustainability reports and financial performance has begun to be carried out. However, most of the research that has been done shows results that have not been consistent. The purpose of this study was to examine the effect of sustainability report which was described as economic performance disclosure, environmental performance disclosure, and social performance disclosure on corporate financial performance and its implications for company value. The study was conducted on winner companies based on NCSR categories and also listed as issuers on the Indonesia Stock Exchange (IDX) during 2015-2017. Research analysis using Partial Least Square (PLS). The results of the study show that Sustainability reporting has an effect on the profitability of disclosures related to aspects of economic performance and environmental performance, while aspects of social performance have no effect on profitability. Sustainability reporting based on aspects of economic, environmental and social performance has an effect on company value. Financial performance cannot mediate the effect of sustainability reporting based on aspects of economic performance, social performance and environmental performance on firm value.Keywords. sustainibility reporting; financial performance; firm valueAbstrak. Seiring dengan semakin banyaknya perusahaan di Indonesia yang mempublikasikan sustainability report, maka tren penelitian tentang hubungan antara sustainability report dan kinerja keuangan mulai banyak dilakukan. Namun demikian, sebagian besar penelitian yang telah dilakukan menunjukkan hasil yang belum konsisten. Tujuan dari penelitian ini adalah untuk menguji pengaruh sustainability report yang dijabarkan menjadi economic performance disclosure, environmental performance disclosure, dan social performance disclosure terhadap kinerja keuangan perusahaan serta implikasinya terhadap nilai perusahaan yang dilakukan Penelitian dilakukan terhadap perusahaan winner berdasarkan kategori dari NCSR dan tercatat pula sebagai emiten pada Bursa Efek Indonesia (BEI) selama 2015 -2017. Analisis penelitian menggunakan Partial Least Square (PLS). Hasil penelitian menunjukan bahwa Sustainability reporting yang berpengaruh terhadap profitabilitas pengungkapan yang berkaitan dengan aspek kinerja ekonomi dan kinerja lingkungan, sedangkan aspek kinerja sosial tidak berpengaruh terhadap profitabilitas. Sustainability reporting berdasarkan aspek kinerja ekonomi, lingkungan dan sosial berpengaruh terhadap nilai perusahaan. Kinerja keuangan tidak dapat memediasi pengaruh sustainability reporting berdasarkan aspek kinerja ekonomi, kinerja sosial dan kinerja lingkungan terhadap nilai perusahaan.Kata Kunci. sustainibility reporting; kinerja keuangan; nilai perusahaan