bluuebunny/crossref_metadata_2025_split huggingface dataset:
Microarray Gene Expression Data Generation and Pre-Processing of Moringa Oleifera Leaves for the Improvement of Medicinal Use
Authors: Shittu Umar 
Published: April 2023

Moringa oleifera is a plant species belonging to the family name called Moringaceae widely cultivated for human use. This study aimed to generate microarray gene expression data from the leaves of the Moringa oleifera plant and explore the usage of some tools available in the Bioconductor R package for the quality control. Six (6) young Moringa Oleifera leaves (YMOL) samples and six (6) old Moringa oleifera leaves (OMOL) samples were collected from the plant and processed for microarray data generation. Microarray gene expression raw data from the leaves of the Moringa oleifera plants were generated, each in a CEL file format and the usage of some tools available in R programming Bioconductor open source and development software project were explored for the quality control of the data. Affycoretools were installed in the R environment for pre-processing of microarray raw data. AffyQCReport tools were used to generate a comprehensive quality control (QC) report for the microarray unnormalized raw data in PDF format. It is recommended that Gene chip robust multiarray analysis (GCRMA) method can be used for visual inspection, background correction, normalization and summarization of this microarray raw data. The normalized microarray raw data can be used through the genetic engineering to improve the Moringa oleifera plant medicinal values in order to solve some medical problems especially with patients suffering from diabetes and hypertension and also can be of enormous importance in the fields of pharmacy and medicine at large.
Architecture, Opportunity, and Conflict in Eighteenth-Century Sicily
Authors: Nixon Martin 
Published: April 2023

The catastrophic Sicilian earthquake of 1693 led to the rebuilding of over 60 towns in the island’s south-west. The rebuilding extended into the eighteenth century and gave opportunities for the reassertion and the transformation of power relations. Although eight of the towns are now protected by UNESCO, the remarkable architecture resulting from this rebuilding is little known outside Sicily.
This is the first book-length study in English of this interesting area of early modern architecture. Rather than seek to address all of the towns, five case studies discuss key aspects of the rebuilding by approaching the architecture from different scales, from that of a whole town to parts of a town, or single buildings, or parts of buildings and their decoration. Each case study also investigates a different theoretical assumption in architecture, including ideas of the Baroque, rational planning, and the relegation of decoration in architectural discourse.
Paracentral acute middle maculopathy progressing to central retinal artery occlusion following coronavirus disease vaccination: a multimodal imaging report
Authors: Sanjay Srinivasan , Sharief Shama , Gopikrishna Gadde Santosh , Gowda Poornachandra B 
Published: April 2023

Background: Coronavirus disease (COVID-19) vaccines can cause adverse ocular effects, including vascular insults, acute macular neuroretinopathy, paracentral acute middle maculopathy (PAMM), ophthalmic vein thrombosis, Graves’ disease, arteritic anterior ischemic optic neuropathy (A-AION), and nonarteritic AION. Here, we report a case of unilateral PAMM progressing to central retinal artery occlusion (CRAO) after COVID-19 vaccination, identified using multimodal imaging.
Case Presentation: A 24-year-old healthy man presented with unilateral progressive blurring of vision in the right eye. He had a recent history of fever without rashes 2 weeks after coronavirus disease vaccination. He was diagnosed with PAMM in the right eye at a local hospital and treated with a tapering dose of oral steroids. At presentation, he showed progressive blurring of vision in the right eye and the best-corrected distance visual acuity (BCDVA) was 20/60. The anterior segment was normal. Fundus examination revealed a pale optic disc with arteriolar attenuation and barrage laser scarring at the inferotemporal periphery. CRAO was diagnosed based on the right eye findings. The patient underwent multimodal imaging, including wide-field fundus photography using Optos® (Optos Carfornia®, Optos Inc., Dunfermline, United Kingdom), multicolor imaging with Spectralis™ (Heidelberg Retinal Angiograph; Heidelberg Engineering, Inc., Dossenheim, Germany), fundus fluorescence angiography (Heidelberg Retinal Angiograph; Heidelberg Engineering, Inc., Dossenheim, Germany), and optical coherence tomography angiography (ANGIOVUE, OPTOVUE, Inc., Fremont, CA, USA) using the split-spectrum amplitude-decorrelation angiography algorithm. The condition progressed from PAMM to CRAO during the oral steroid treatment course. At the 2-month follow-up, the right eye BCDVA had improved to 20/50, with fundus findings remaining the same as at the previous visit.
Conclusions: This was the first report of a young patient with PAMM presenting with focal vascular occlusion that evolved to global occlusion in the form of CRAO in the absence of systemic vascular risk factors and with a normal coagulation profile. This case suggests that arterial occlusion may exert a temporary effect secondary to COVISHIELD™ vaccination. Randomized controlled trials and case – control studies on the role of vaccination in precipitating thromboembolic events in healthy individuals would provide insight into the causation.
ANALISIS RESPON SISWA DALAM IMPLEMENTASI MENYUSURI LIKA LIKU SUNGAI KEHIDUPAN MAJAPAHIT PADA SETIAP FASE PLAN, DO, SEE PADA KURIKULUM SMK PUSAT KEUNGGULAN.
Authors: Shofa Nina Ariani 
Published: April 2023

Vocational High School is a vocational school that is able to produce graduates who are competent in certain skills and are absorbed in the business world, industry, and the world of work and can continue to higher education levels, through a program of synchronizing vocational education in a systemic and comprehensive manner with the business world, industry, and the world. working world. The final target of this program is to make reference vocational schools that can function as centers of excellence, quality improvement and referrals for other vocational schools. In the curriculum spectrum in the PK Vocational School program, history subjects are included in the general subject group which focuses on forming students into complete individuals according to the developmental phase, related to the norms of life as beings who believe in YME, individuals, social groups, citizens of the Unitary State of the Republic of Indonesia, and world. The challenge faced by history subjects to achieve the emphasis on general subjects is the growing stigma among students and even the public that history subjects are boring lessons and only contain empty memorization. The river of life was chosen as a learning medium because it describes the flow of a person's life that is not always smooth, full of twists and turns and strategies to face challenges and has a clear end, namely the ocean. This is suitable to be applied as a learning medium for the Hindu-Buddhist kingdoms because the Hindu-Buddhist kingdoms in Indonesia have the same trend pattern, which consists of 3 phases, namely the beginning, the heyday, and the end, namely the period of dim or the period of collapse. The students' responses in the implementation of walking the twists and turns of the Majapahit river of life were very good and made it easier to understand the Majapahit material.
Keyword : , , Do, See, Majapahit, SMK PK
Analisis Partisipasi Masyarakat Dalam Pelaksanaan Pembangunan Desa Untuk Mengoptimalkan Kesejahteraan Masyarakat Di Desa Bandar Klippa, Kecamatan Percut Sei Tuan, Kabupaten Deli Serdang
Authors: Panjaitan Maringan , Pandiangan Evi Phaninora 
Published: April 2023

The role of participation in the implementation of village development is a very important component for the success of the village development program. So that community participation can run optimally. Therefore, the village government should play an active role in developing community participation in the implementation of development programs. The purpose of this study is to find out how community participation in the implementation of village development is to optimize community welfare. This study uses a qualitative descriptive research method using interview and observation techniques. This study uses "key informants, main informants and additional informants".
The result shows that the process of community participation in the implementation of village development is quite good, starting from decision making, implementation of development and evaluation of development. Where the community already has the responsibility in village development, participates in the implementation and participates in the evaluation of development. But there are factors that hinder the process of community participation in the implementation of village development, namely the village government does not have the ability to explain to the community what development will be carried out so that people do not understand and do not understand which results in people not wanting to participate in village development.
The conclusion from the results of this study is that community participation in the implementation of village development in Bandar Klippa Village is quite good, as can be seen from the enthusiasm of the community in implementing village development.
МҮМКІНДІГІ ШЕКТЕУЛІ БАЛАЛАРДЫ ӘЛЕУМЕТТЕНДІРУ ЕРЕКШІЛІКТЕРІ
Authors: Мовкебаева З.А. , Книсарина М.М. , Габиткызы Г.Т. , Женискызы А. , Каримова А.А. 
Published: April 2023

В статье определены особенности социализации детей с ограниченными возможностями. Процесс социализации сложен для детей с различными проблемами развития. Здесь на первый план выдвигается проблема подготовки этих детей к самостоятельной жизни и работе, т.е. интеграция их в окружающий социум, в сообщество обычных детей, что может быть достигнуто специальными мерами, связанными с психолого-педагогическим сопровождением в процессе обучения и воспитания.
Мақалада мүмкіндігі шектеулі балалардың әлеуметтену ерекшеліктері анықталған. Әлеуметтенупроцесі әртүрлі даму проблемалары бар балалар үшін қиын. Мұнда бұл балаларды тәуелсіз өмірге жәнежұмысқа дайындау мәселесі, яғни оларды қоршаған қоғамға, қарапайым балалар қауымдастығына біріктіру, бұған оқыту мен тәрбиелеу процесінде психологиялық-педагогикалық қолдауға байланысты арнайы шаралар қол жеткізуге болады.
СӨЙЛЕУ ТІЛІ ЖАЛПЫ ДАМЫМАҒАН БАЛАЛАРМЕН АРНАЙЫ БАҒЫТТАЛҒАН ТҮЗЕТУ ЖҰМЫСТАРЫ
Authors: Baytokova G.S. 
Published: April 2023

In correctional work with children with speech defects, articulations of pronunciation of sounds, work on working out, distinguishing sounds, game exercises for the development of small movements with words are shown and the organization of speech therapy work is presented. These exercises can be used in the process of training, education, in general and individual types of work.Keywords: articulation, pathology, phonemic hearing, language deafness, phrases
Сөйлеу тілінде кемістігі бар балалармен жүргізілетін түзету жұмысындадыбыстардың айтылу артикуляциялары, дыбыстарды машықтандыру, ажырату жұмыстары, сөзұйқастармен ұсақ қозғалыстардың дамуына ойын жаттығулар көрсетілген және логопедиялық жұмыстың ұйымдастырылуы ұсынылған. Берілген жаттығуларды оқыту, тәрбиелеу үрдісінде, жалпы және жеке жұмыс түрлерінде қолдануға болады.
В коррекционной работе с детьми с дефектами речи показаны артикуляции произношения звуков, работа по отработке, различению звуков, игровые упражнения на развитие мелких движений со словами и представлена организация логопедической работы. Данные упражнения могут быть использованы в процессе обучения, воспитания, в общих и индивидуальных видах работы.
Carbon emissions and radiative forcings from tundra wildfires in the Yukon–Kuskokwim River Delta, Alaska
Authors: Moubarak Michael , Sistla Seeta , Potter Stefano , Natali Susan M. , Rogers Brendan M. 
Published: April 2023

Abstract. Tundra environments are experiencing elevated levels of wildfire, and the
frequency is expected to keep increasing due to rapid climate change in the
Arctic. Tundra wildfires can release globally significant amounts of
greenhouse gasses that influence the Earth's radiative balance. Here we
develop a novel method for estimating carbon loss and the resulting
radiative forcings of gaseous and aerosol emissions from the 2015 tundra
wildfires in the Yukon–Kuskokwim Delta (YKD), Alaska. We paired burn depth
measurements using two vegetative reference points that survived the fire
event – Sphagnum fuscum and Dicranum spp. – with measurements of local organic matter and soil carbon
properties to estimate total ecosystem organic matter and carbon loss. We
used remotely sensed data on fire severity from Landsat 8 to scale our
measured losses to the entire fire-affected area, with an estimated total
loss of 2.04 Tg of organic matter and 0.91 Tg of carbon and an average loss
of 3.76 kg m−2 of organic matter and 1.68 kg m−2 of carbon in the
2015 YKD wildfires. To demonstrate the impact of these fires on the Earth's
radiation budget, we developed a simple but comprehensive framework to
estimate the radiative forcing from Arctic wildfires. We synthesized
existing research on the lifetime and radiative forcings of gaseous and
aerosol emissions of CO2, N2O, CH4, O3 and its
precursors, and fire aerosols. The model shows a net positive cumulative
mean radiative forcing of 3.67 W m−2 using representative concentration pathway (RCP) 4.5 and 3.37 W m−2
using RCP 8.5 at 80 years post-fire, which was dominated by CO2
emissions. Our results highlight the climate impact of tundra wildfires,
which positively reinforce climate warming and increased fire frequency
through the radiative forcings of their gaseous emissions.
Rodríguez Melchor, María Dolores (coord.): La pervivencia y reescritura del mito: adaptación, traducción y recepción. McGraw Hill. 2022, 124 págs. ISBN 9788448634629
Authors: Ortiz de Urbina Sobrino Paloma 
Published: April 2023

Reseña del libro
Rodríguez Melchor, María Dolores (coord.): La pervivencia y reescritura del mito: adaptación, traducción y recepción. McGraw Hill. 2022, 124 págs. ISBN 9788448634629, 124 p.
Persebaran Fungsi Kualitas Quality Function Deployment (QFD) di Bidang Manufaktur: Kajian Literatur
Authors: Setianah Puput , Herlina Lina , Pamenta Markus , Purba Humiras Hardi 
Published: April 2023

Di era globalisasi ini, semua industri harus mampu bersaing di pasar global agar tetap kompetitif. Pasar global yang intense telah mendorong semua industri untuk terus meningkatkan daya saing mereka. Diantara semua sektor industri, industri manufaktur merupakan salah satu industri yang sangat menentukan dalam meningkatkan perekonomian dan pendapatan nasional. Makalah ini bertujuan untuk memberikan tinjauan pustaka tentang penerapan QFD dalam industri manufaktur dan memberikan pengetahuan kontekstual sebagai sarana untuk meningkatkan penerapan QFD dalam industri manufaktur. Metode yang digunakan adalah sistematik literatur review. Hasil penelitian menunjukkan bahwa QFD merupakan suatu pendekatan yang dapat membantu perusahaan meningkatkan kualitas baik layanan maupun produk dengan menerjemahkan keinginan konsumen ke dalam karakteristik teknis perusahaan. Dari hasil kajian literatur yang dianalisis, fokus utama QFD adalah pendekatan yang dapat digunakan untuk meningkatkan produk pada industri manufaktur agar dapat menghasilkan keluaran sesuai dengan selera dan keinginan konsumen dimana QFD telah berkembang menjadi alat yang ampuh untuk meningkatkan kualitas layanan dan produk yang berfokus pada kebutuhan pelanggan.
GASTRITIS Y Helicobacter pylori CORRELACIÓN ENDOSCÓPICA, HISTOPATOLÓGICA Y SEROLÓGICA EN PACIENTES DEL HOSPITAL MILITAR DE ENERO A MARZO 2013 (TRABAJO PRESENTADO EN EL XXI CONGRESO MUNDIAL IOCIM)
Authors: Marañón Zelada María Rosario , Parra Marañón David Eduardo , López Fuentes Verónica , Córdova Marañón Elizabeth , Parra Marañón Juan Diego 
Published: April 2023

El Helicobacter pylori (H pylori) es una bacteria en forma de espiral o en S que se encuentra en la mucosa que recubre el estómago, daña el tejido estomacal y duodenal, causando inflamación y úlceras. El descubrimiento del Helicobacter en 1982 y su implicación clínica en las enfermedades gastrointestinales ha sido considerado uno de los principales hallazgos de la gastroenterología.
La Agencia Internacional para la Investigación del Cáncer (IARC) demostró la asociación entre la infección por Helicobacter pylori y el cáncer gástrico. A pesar de que se ha observado una disminución general de la incidencia de este cáncer, sigue siendo el cuarto tipo más común y la segunda causa de muerte por cáncer en todo el mundo.
El Helicobacter afecta a cerca de dos tercios de la población mundial y su prevalencia está fuertemente relacionada con las condiciones socioeconómicas. En países en vía de desarrollo, afecta a más de 80% de los adultos en contraste con el 20% en países desarrollados.
PESQUISAJE	PRENATAL DE HEMOGLOBINOPATÍAS SS Y CC: 25 AÑOS DE EXPERIENCIA EN LA PROVINCIA DE VILLA CLARA, CUBA
Authors: Taboada Lugo Noel , Gómez Rojo Melba , Algora Hernández Ana E. , Arcas Ermeso Gretsy , Noa Machado María D. , Herrera Martínez Manuela 
Published: April 2023

Hemoglobinopatías es el término médico que designa a un grupo de trastornos que afectan a las células rojas de las sangre. El estado homocigoto para la hemoglobina S es la forma más común y severa, aunque también se incluyen heterocigotos compuestos para la hemoglobina S
Se realizó un estudio observacional, descriptivo y transversal donde se exponen los resultados de 25 años del programa de pesquisaje prenatal de hemoglobinopatías SS y SC en la provincia Villa Clara, Cuba, en el período comprendido de 1988 a 2012.
Se diagnosticaron 4 660 embarazadas portadoras de estas hemoglobinopatías y se estudiaron 4 193 cónyuges. Se identificaron 144 parejas de alto riesgo y 126 de ellas aceptaron procedimientos de diagnóstico prenatal. Se diagnosticaron 24 fetos afectados, de los cuales en 17 casos la pareja decidió la interrupción electiva de la gestación. La tasa de prevalencia ajustada de estas hemoglobinopatías en Villa Clara durante el periodo estudiado fue de 0,95 por 10 000 nacidos vivos.
Papilomas orales: una presentación simultánea de hiperplasia epitelial multifocal y papilomas escamosos en un paciente joven de la Clínica Odontológica UNIVALLE La Paz
Authors: Flores Ramos Janeth Liliam , Salazar Guerra Leonardo , Feraudy Fournier Nelly Carolina , Mollo López Judith Rocío , Choque Gutiérrez Eve , Garnica Guzmán Alejandra 
Published: April 2023

Los papilomas orales son lesiones benignas provocadas por el virus del papiloma humano, que infectan las células epiteliales basales de la piel y las mucosas. Las lesiones orales causadas por la infección del virus del papiloma humano incluyen el papiloma escamoso, la verruga vulgar, el condiloma acuminado y la hiperplasia epitelial multifocal.
Se presenta el caso de un paciente de 16 años con papilomas orales, con una presentación simultánea de papilomas escamosos a nivel de la lengua y una hiperplasia epitelial multifocal en la mucosa labial y retrocomisural. El manejo terapéutico fue realizado en la cátedra de Cirugia Bucal en el quirófano de la Clinica Odontológica de la Universidad del Valle Sede La Paz.
Después de obtener el consentimiento escrito por parte del paciente, se procedió a la biopsia excisional de las lesiones. El examen histopatológico mostr6 un epitelio plano estratificado no queratinizado, con disposición papilar y alteración de la polaridad por presencia de células displásicas y coilocitos que ocupan un tercio del espesor del epitelio, estroma fibromuscular e infiltrado inflamatorio linfocitario disperso.
El profesional del área de la salud debe estar familiarizado con los papilomas orales, para poder identificarlos, evitar contagios y la extensión de los mismos a otros sectores de la cavidad oral y para realizar el tratamiento oportuno de estas lesiones.
Wacana Kritis Karakter Tokoh Marni dan Rahayu dalam Novel Entrok Karya Okky Madasari
Authors: Saputro Muhammad Ricko Aji , Utami Sri 
Published: April 2023

Analisis Wacana Kritis merupakan salah satu metode yang dapat digunakan untuk menganalisis wacana baik lisan maupun tulis. Objek dari analisis wacana kritis (Critical Discourse Analysis) adalah bahasa, sama halnya dengan analisis wacana (Discourse Analysis). Namun dalam analisis wacana kritis, tidak hanya aspek bahasa saja yang diteliti namun termasuk pula konteks yang menyertainya. Model Van Dijk adalah model yang paling banyak dipakai. Hal ini mungkin disebabkan karena Van Dijk menformulasikan elemen-elemen wacana, sehingga bisa dipakai secara praktis. Menurut Van Dijk, penelitian atas wacana tidak cukup hanya didasarkan pada analisis teks semata, karena teks hanya hasil dari suatu praktik produksi yang harus juga diamati. Penelitian ini dilaksanakan dengan tujuan mendiskripsikan suatu hal, yakni mencakup wacana kritis karakter tokoh Marni dan Rahayu dalam novel “Entrok” karya Okky Madasari. Penelitian ini menggunakan metode jenis deskriptif kualitatif. Sumber Data peneltian berupa paparan kebahasan berbentuk kalimat. Pengumpulan data-data menggunakan teknik simak dan catat. Instrumen yang dipergunakan untuk mengumpulkan data berupa manusia, yaitu peneliti sendiri. Demi menjaga keabsahan data, dilakukan kegiatan triangulasi data. Kegiatan analisis data dimulai dari tahap deskripsi data, analisis data, serta pembahasan. Berdasarkan hasil analisis tersebut, simpulan yang bisa didapat dari analisis data wacana kritis karakter tokoh Rahayu adalah berbagai macam karakter (sifat) muncul pada saat sang tokoh mengalami kejadian apapun. Tokoh Rahayu tidak begitu berbanding terbalik dengan ibunya (Marni).
Algunos credos más notables
Authors: Resines Llorente Luis 
Published: April 2023

Con frecuencia, se ha presentado el Credo como una oración que los cristianos han de saber y recitar. Y ha sido menos frecuente presentarlo como una síntesis de la fe poseída, la fe sabida, la fe profesada. En realidad, esta segunda perspectiva es la que le corresponde desde sus orígenes, y cada cristiano, cada comunidad cristiana, ha expresado su fe con frases similares, parecidas, pero no siempre idénticas. Esto no es ruptura de la fe, sino riqueza de la expresión sincera.
El examen de unos cuantos credos, más notables, permite una reflexión, al compararlos, y comprobar de cuántas maneras es posible manifestar la misma fe con fórmulas diferentes en sus frases, pero idénticas en su más honda entraña. Es la riqueza del patrimonio de los cristianos.