bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nano composites of PAM Reinforced with Al2O3
Authors: Al-dabbag Balqees M. , Kadhim Hanaa Jawad 
Published: April 2023

الهدف من هذا البحث هو تحديد مدى تأثير نسب الوزن المختلفة لجسيمات الألومينا النانوية بنسب وزنية مختلفة تشمل 0.02 ، 0.04، و 0.06 في المائة نسبة وزنية على الخصائص الفيزيائية لبولي أكريلاميد (PAAM) . تم استخدام جهاز الخلاط المغناطيسي الحراري للحصول على المحاليل من إذابة 10 غم من مسحوق بولي أكريلاميد في 90 غم من الماء المقطر المؤين لمدة 4 ساعات لإنتاج محلول PAAM بتركيز 0.11 غم / مل . تم تقسيم المحلول الناتج الى أربعة أقسام متساوية من المحلول ، كل منها بحجم 20 مل. تمت إضافة دقائق الالومينا النانوية لكل محلول بشكل مستقل بنسب مختلفة 0.0 ، 0.02 ، 0.04 ، 0.06 لتكوين أربعة محاليل نانوية سائلة بمحتويات مختلفة من جسيمات الألومينا النانوية بناءً على كل نسبة وزن. تم استخدام عملية الصب اليدوي لعينات المركبات النانوية ، والتي تضمنت صب المحلول المحضر في قالب من البلاستيك بحجم مناسب وتركت المحاليل لمدة 24 ساعة لاتمام عملية التصلب لإنشاء أغشية النانو المركبة ، ثم قطع الغشاء الرقيق الناتج وفقًا لكل اختبار ،. تم استخدام اختبار الشد لدراسة قوة الشد ، ومعامل يونك ، والاستطالة ، والمتانة. بالإضافة إلى ذلك ، تم إجراء اختبار الأشعة تحت الحمراء (FTIR) لفحص الروابط الكيميائية والفيزيائية بين بولي أكريلاميد وجسيمات الألومينا النانوية. تم فحص مورفولوجيا السطح باستخدام جهاز المجهر الالكتروني الماسح. تم اختبار زوايا الترطيب للعينات لتحديد السلوك اتجاه الماء لهذه العينات.. أظهرت النتائج أن اضافة جسيمات الألومينا النانوية الى البولي اكريل امايد يحسن الخصائص الميكانيكية للمركبات النانوية الناتجة. تزداد قوة الشد من 1 كيكا باسكال إلى 2.5 كيكا باسكال مع زيادة محتوى الألومينا النانوية من 0 إلى 0.06٪ نسبة وزنية .و بالنسبة لنفس النسب السابقة ، زاد معامل يونك كذلك ، حيث ارتفع من 1.3 إلى 2 كيكا باسكال للنسبة الوزنية لجسيمات الألومينا النانوية 0.04 بالمائة بالوزن ، ترتفع المتانة إلى 240 جول / سم 2. من ناحية أخرى ، أدت إضافة دقائق الألومينا النانوية إلى زيادة زاوية التبلل لسطح PAAM من 55 درجة إلى 67 درجة ، وأظهرت سلوكًا محبًا للماء .
Continuous Methane Monitoring: Equivalency Evaluation of Regulator-Approved Alternative Leak Detection and Repair Program in Alberta, Canada
Authors: Benko Tim , MacGregor Alex , Wen Eric , Fox Thomas , Moorhouse Brendan 
Published: April 2023

Summary
Diverse methods have emerged for methane leak detection and repair (LDAR), alongside a growing interest in continuous monitoring (CM). Novel LDAR programs must demonstrate equivalent (or better) emissions reductions compared to conventional handheld methods to be approved by regulators and trusted by industry. We apply and test a widely accepted equivalency framework and report on a regulatory approved alternative LDAR pilot program to evaluate the performance of CM relative to conventional LDAR. The framework, which has not been formally tested to date, relies on a combination of controlled release testing, simulation modeling, and field piloting. First, controlled release testing at known emission rates is used to establish probability of detection functions and other performance metrics for the CM device. Performance metrics are then used to build a CM module in LDAR Simulator (LDAR-Sim), an open-access modeling framework. Finally, CM devices are deployed as part of a field pilot.
Controlled release testing results and dispersion modeling suggest that the CM devices can reliably detect (i.e., 90% detection probability or greater) a rate of 1 kg/h (~54 scf/hr) from distances of 75–100 m with no false positive detections. A set of work practices were established using the LDAR-Sim framework. The CM program requires close-range follow-up for any detection event and is estimated by LDAR-Sim to reduce aggregate annual fugitive methane emissions by 91.8% relative to the baseline, doubling the reductions anticipated from a conventional regulatory program. For the pilot, 52 devices are deployed across 16 facilities with Enhance Energy. All devices are positioned within 100 m of monitored assets. Each time devices record a detection event, which is defined as a sustained anomaly three standard deviations above a moving average background concentration for 24 hours, 7 days, or 60 days, the operator performs a close-range follow-up inspection. Preliminary results show that the CM devices can detect leaks and that follow-up protocols are effective at immediately finding leaks and avoiding false positives. Confirmed detections include fugitive emissions such as a tank thief hatch leak and vented emissions including high-bleed pneumatics. Both types of emissions were confirmed as repaired or improved by CM. These results indicate that repairing leaks more expeditiously through faster detection can reduce emissions by up to 90%.
Transfer Learning with Prior Data-Driven Models from Multiple Unconventional Fields
Authors: Cornelio Jodel , Mohd Razak Syamil , Cho Young , Liu Hui-Hai , Vaidya Ravimadhav , Jafarpour Behnam 
Published: April 2023

Summary
Constructing reliable data-driven models to predict well production performance (e.g., estimated ultimate recovery, cumulative production, production curves, etc.) for unconventional reservoirs requires large amounts of data. However, when considering unconventional reservoirs in their early stages of development, where data and the wells drilled are limited, one may benefit from leveraging available data and/or pretrained models from other more developed fields. Transfer learning, the process of storing knowledge gained while solving one problem (source data) and applying it to solve a different but related problem (target data), provides a workflow for alleviating data needs in training a data-driven model in fields with limited data. However, a pitfall in the application of transfer learning is the possibility of negative transfer, that is, transferring incorrect or irrelevant knowledge to the target data. In particular, the black-box nature of most data-driven models, e.g., neural networks, support vector machines, and random forest, makes it difficult to completely interpret the contribution of different source models used for knowledge transfer. Hence, ranking the viability of source models for transfer learning can reduce the risk of negative transfer and improve the prediction performance. In this paper, we illustrate the impact of negative transfer and how it can be identified, and present a new approach for ranking multiple source models based on their positive transfer contribution. Finally, we propose a framework to build a reliable model to predict well production performance by combining multiple sources of information into one network to be transferred and retrained with limited data in fields at their early stages of development.
A community-based Advanced Nurse Practitioner-led integrated oncology care model for adults receiving oral anticancer medication: A pilot study
Authors: richmond janice , kelly mary grace , johnston alison , murphy patrick j , O'connor laura , gillespie paddy , hobbins anna , Alvarez-Iglesias alberto , murphy andrew w 
Published: April 2023

Abstract
Oral anti-cancer medications (OAMs) are being used increasingly within cancer care. OAMs offer the potential to improve patient convenience and increase hospital capacity. The clinical assessment for each cycle of OAMs requires specialist patient review often performed in the acute hospital. Consequently, any improvement in patient expediency or increased hospital capacity is not realised. This study aimed to develop and pilot the specialist assessment of patients receiving OAMs by an Advanced Nurse Practitioner (ANP) in a community setting.
The primary aim of this pilot study was to assess the feasibility of a community-based ANP-led integrated oncology care model for adults receiving OAMs in Ireland who met the pre-specified eligibility criteria. The objectives were to determine the feasibility of a definitive trial of this intervention by measuring patient safety, acceptability to patients and staff and cost of the new model of care.
This single-centre pilot study provided patient care (n = 37) to those receiving OAM therapies within a community setting for a 4-month period. Consent rate was high with no attrition other than for clinical reasons. There were 151 contacts with the sample during that time.
Results demonstrated that the ANP-led intervention and new model for OAM care was safe, highly acceptable to patients and staff and that related healthcare costs could be captured. Based on the success of this pilot study the authors conclude that an ANP-led integrated oncology care model for adults receiving OAMs within a community setting is feasible, and a definitive trial is warranted.
Trial Registration
Trial registration: ISRCTN, ISRCTN10401455. Registered 30 November 2020, https://doi.org/10.1186/ISRCTN10401455
Synergistic effects of Li&amp;Na co-doping enabling flexible Cu2ZnSn(S,Se)4 solar cells with over 10% certified efficiency
Authors: Cheng Shuying , Sun Quanzhen , Shi Chen , Xie Weihao , Li Yifan , Li Yaling , Zhang Caixia , Wu Jionghua , Zheng Qiao , Deng Hui 
Published: April 2023

Abstract
Double ion doping is an effective strategy for efficiently flexible Cu2ZnSn(S,Se)4 (CZTSSe) solar cells, simultaneously relieving the adverse effects of various defects. Here, a Li&Na co-doped strategy is applied to synergistically inhibit the detrimental bulk defects in CZTSSe absorbers and improve the devices performances. A power conversion efficiency (PCE) of 10.53% with certified 10.12% for the flexible CZTSSe solar cell has been achieved. The space charge limited current (SCLC) and temperature-dependent conductivity (TDC) characterizations show that Li incorporation passivates harmful CuZn anti-site defects and Na incorporation increases beneficial defects in the CZTSSe films. Synergistic effects of Li and Na incorporations increase carrier concentration and reduce the interfacial defects, thereby enhancing Voc by 19.76% compared with the undoped device. In addition, profiting from the high-performance small-area (0.205 cm2) devices, we achieve a large-area (2.38 cm2) flexible CZTSSe device with a 9.41% PCE. The co-doping investigation to alter the characteristics of detrimental defects provides a new perspective for efficiently flexible CZTSSe solar cells.
An economic decision-making model of anticipated surprise with dynamic expectation
Authors: Chan Ho Ka , Toyoizumi Taro 
Published: April 2023

Abstract
When making decisions under risk, people often exhibit behaviors that classical economic theories cannot explain. Newer models that attempt to account for these ‘irrational’ behaviors often lack neuropsychological bases and require introduction of subjective and problem-specific constructs. Neuroscience findings, like prediction error signals and introspective neuronal replay, as well as psychological theories like affective forecasting, suggest that people mentally simulate outcomes of events and anticipate their potential effects. Inspired by this, we propose a model in which decisions are chosen based on an entity which we call the ‘anticipated surprise’, defined by a nonlinear average of the differences between individual outcomes and a reference point. The reference point is determined by the expected value of the possible outcomes, which we assume to be dynamically changing during the mental simulation of a sequence of events. We illustrate how our model explains prominent economic paradoxes and gambling behaviors by considering the mental simulation of outcome resolution of the corresponding decision-making problems and interpreting those problems as compound lotteries. Our work could point towards an objective, potentially measurable quantity that describes the perceived ‘subjectiveness’ arising from emotional aspects in decision-making processes when evaluating predicted event outcomes.
Linkage to Hospital Pharmacy for Rifaximin Receipt Prior to Discharge from Hospitalization with Hepatic Encephalopathy Reduces Early Readmissions in Patients with Liver Cirrhosis: A Quality Improvement Project
Authors: Nwankwo Eugene , Annakie David , DO Ameya Deshmukh , DO Parth Desai , Jain Ritika , Tripathi Rohan , Qureshi Kamran 
Published: April 2023

Abstract
Background and Aims
Hepatic Encephalopathy (HE) leads to multiple hospitalizations in liver cirrhosis. This imposes a significant burden on patients caregivers, and the healthcare system. Rifaximin reduces HE recurrence and hospitalizations, but many patients are not able to receive Rifaximin promptly after hospitalizations due to gaps in the prior authorization process and insurance coverage. This study shows the results of the Quality Improvement (QI) project aimed at improving access to Rifaximin by utilization of hospital pharmacy to provide Rifaximin at bedside or soon after hospital discharge with HE.
Methods
A retrospective analysis of 124 patients admitted to our hospital with recurrent HE was performed. All selected patients had Rifaximin prescribed for the first time during a hospitalization (index hospitalization). Both 30-day and 60-day liver-related hospitalizations were recorded for these patients. 80 patients were included in the intervention group when the hospital pharmacy was notified of the Rifaximin prescription prior to discharge as part of a QI project (Group A). Control (Group-B) group included 44 patients who had admission and were prescribed Rifaximin at discharge, prior to initiation of our QI project.
Results
The number of patients who had a re-admission after index hospitalization with HE was lower in Group A compared to Group B (48% vs 73%, p=0.002 for re-admission within 30 days; 56% vs 73%, p=0.007 for re-admission within 60 days respectively). Total hospitalizations decreased in Group A (reduced by 32%, and 59% for the 30-day and 60-day time frame, respectively) compared to Group B. The median days to readmission in Group A was 32, compared to 10 in Group B after the index hospitalization.
Conclusion
Providing Rifaximin to patients with recurrent HE before or soon after discharge from HE-related hospitalization reduced readmission rates for liver-related admissions at our hospital. A significantly higher number of patients did not require early readmission when Rifaximin was provided by the hospital pharmacy. This intervention could lead to lower costs, fewer complications related to frequent hospitalization, and thus reduced healthcare burden.
The prevalence and molecular detection of bovine cysticercosis and its impact on slaughtered cattle in Egypt
Authors: El-Dakhly Khaled Mohamed , Hany Shaimaa Ahmed , Arafa Waleed M. , Abdel-Fatah Omima Ramadan , Abdel-Atty Nasser Sayed , El-Nahass El-Shaymaa 
Published: April 2023

Abstract

Cysticercus bovis is the metacestode of the commonly defined foodborne cestode, Taenia saginata. It infects heart, masseter muscles and other muscular sites of cattle causing bovine cysticercosis. So, a retrospective study using archival documents from authorized agencies is done during the period of 2018–2020 with estimating economic losses. Cysts were collected from municipal Beni-Suef and Basatin abattoirs. Molecular approach including cPCR and sequencing analysis is used to prove the species. The prevalence was 0.34% in Beni-Suef abattoir and 5.70% in Basatin abattoir including heads, hearts or all carcasses condemned. Among 27 provinces surveyed, the highest prevalence was recorded in Aswan followed by Cairo, Suez and Red Sea. Moreover, 19 provinces (Cairo, Alexandria, Suez, Dakahlia, Sharkia, Qalyobia, Kafrelsheikh, Gharbia, Menofiya, Ismailia, Giza, Beni-Suef, Assiut, Sohag, Qena, Aswan, Red Sea, South Sinai and El-Wadi El-Gadid) recorded bovine cysticercosis in 2018, 2019 and 2020. On the other hand, Luxor and North Sinai had no infections. The percentages of condemnation among slaughtered cattle were 1.38, 1.49 and 0.87% in 2018, 2019 and 2020, respectively. Condemnations significantly varied among north, middle and south districts of Egypt, and also varied annually. Molecularly, a diagnostic band at an amplicon size 253 bp targeting the COI gene specific for Cycticercus bovis was revealed. The obtained sequences showed 100% identity with the different Taenia saginata COI GB sequence isolates in many countries worldwide. The phylogenetic analysis method showed that the obtained sequences originating from the same clade of Taenia saginata GB isolates globally. Careful meat inspection as well as strict hygienic measures is recommended for both veterinarians and public.
Ocular hypotony precipitated by Tube Trimming in a uveitic eye with Descemet Membrane Stripping Automated Endothelial Keratoplasty and prior tube revision
Authors: Lee Jackson Chee Chea , Chan Geoffrey Zhi Peng , Georgoulas Stylianos 
Published: April 2023

Abstract
Background To describe ocular hypotony precipitated by trimming of a glaucoma shunt tube in an eye with uveitic glaucoma, a failed Descemet Membrane Stripping Automated Endothelial Keratoplasty (DSAEK) and prior tube revisions.Case Presentation: A patient in her thirties with uveitic glaucoma of the right eye had endothelial decompensation of a DSAEK graft secondary to corneal endothelial touch from two previous glaucoma drainage implants. She underwent ab-interno tube trimming and subsequently developed postoperative hypotony with intraocular pressure (IOP) of 2 mm Hg. Intraoperative Trypan blue was effectively utilized to make the diagnosis of an over-filtering glaucoma drainage device, despite the presence of an intraluminal stent. Tube ligation was performed, and the IOP increased to 8 mmHg. IOP has remained stable at a 6-month follow-up review.Conclusions Glaucoma shunt tube trimming may be associated with development of ocular hypotony despite minimal manipulation or removal of the associated intraluminal stent in non-valved glaucoma drainage devices. Trypan blue may be considered as a useful diagnostic adjunct for determining the underlying cause of hypotony in such cases.
A Systematic Overview of Fuzzy Random Option Pricing in Discrete Time and a Binomial Extension to Temporal Structure of Interest Rates
Authors: de Andrés-Sánchez Jorge 
Published: April 2023

Abstract

This paper makes a bibliographical analysis of fuzzy set theory (FST) contributions to option pricing with a fuzzy-random approach with detailed attention to those based in the binomial lattice. Likewise, we extend the fuzzy-random approach to yield curve binomial modelling. The bibliographical analysis was performed by applying PRISMA guidelines in the SCOPUS and WoS databases. We first present a structured report of papers about the more general fuzzy-random option pricing (FROP) field and identify principal outlets. Within FROP, we focus on the more concrete fuzzy random discrete time option pricing (FROPDT) in binomial and trinomial lattices, which is developed in greater detail. We detect that this groundwork has been extended to price options on stocks, stock indexes and real options, but no work has been done in the field of the term structure of interest rates and fixed income securities. Thus, we propose a fuzzy extension of the Ho-Lee model that we apply to the European interbank market and to price caplets.
Comprehensive genomic evaluation of advanced and recurrent breast cancer patients for tailored precision treatments
Authors: Ido Mirai , Fujii Kimihito , Mishima Hideyuki , Kubo Akihito , Saito Masayuki , Banno Hirona , Ito Yukie , Goto Manami , Ando Takahito , Mouri Yukako , Kousaka Junko , Imai Tsuneo , Nakano Shogo 
Published: April 2023

Abstract
Aim: The aim of this study was to investigate genetic alterations within breast cancer in the setting of recurrent or de novo stage IV disease.
Patients and Methods: This study included 22 patients with recurrent breast cancer (n=19) and inoperable de novo stage IV breast cancer (n=3). For next generation sequencing, FoundationOneRCDx (F1CDx) (Foundation Medicine Inc., Cambridge, MA, USA) was performed in 21 patients and FoundationOneRLiquid CDx was performed in 1 patient.
Results: Median age was 62.9 years (range, 33.4–82.1). Pathological diagnoses of specimens included invasive ductal carcinoma (n=19), invasive lobular carcinoma (n=2), and invasive micropapillary carcinoma (n=1). F1CDx detected a median of 4.5 variants (range, 1–11). The most commonly altered gene were PIK3CA (n=9), followed by TP53 (n=7), MYC (n=4), PTEN (n=3), and CDH1 (n=3). For hormone receptor-positive patients with PIK3CA mutations, hormonal treatment plus a phosphoinositide 3-kinase inhibitor was recommended as the treatment of choice. Patients in the hormone receptor-negative and no human epidermal growth factor receptor 2 expression group had significantly higher tumor mutational burden than patients in the hormone receptor-positive group. A BRCA2 reversion mutation was revealed by F1CDx in a patient with a deleterious germline BRCA2 mutation during poly ADP ribose polymerase inhibitor treatment.
Conclusion: Guidance on tailored precision therapy with consideration of genomic mutations was possible for some patients with information provided by F1CDx. Clinicians should consider using F1CDx at turning points in the course of the disease.
Randomized Controlled Trial of Motivational Enhancement Interventions to Increase Pre-Exposure Prophylaxis Use in Sexual Minority Men Who Use Stimulants
Authors: Davis-Ewart Leah , Grov Christian , Verhagen Rachel , Manuel Jennifer , Viamonte Michael , Dilworth Samantha , Valentin Omar , Cherenack Emily M. , Carr Sidney , Doblecki-Lewis Susanne , Nahum-Shani Inbal , Carrico Adam W. 
Published: April 2023

Abstract
Background Although pre-exposure prophylaxis (PrEP) could substantially mitigate HIV risk, sexual minority men (SMM) who use stimulants commonly experience difficulties with engaging in PrEP clinical services. Motivational interviewing (MI) and contingency management (CM) reduce substance use and condomless anal sex in this population, but these motivational enhancement interventions require adaptation to promote engagement along the PrEP care continuum.Methods PRISM is a pilot sequential multiple assignment randomized trial (SMART) testing the feasibility, acceptability, and preliminary effectiveness of distinct combinations of telehealth MI and CM in 70 cisgender SMM who use stimulants that are not currently taking PrEP. A national sample was recruited via social networking applications to complete a baseline assessment and mail-in HIV testing. Those with non-reactive HIV results are randomized to receive either: 1) a 2-session MI intervention focusing on PrEP use (session 1) and concomitant stimulant use or condomless anal sex (session 2); or 2) a CM intervention with financial incentives for documented evidence of PrEP clinical evaluation by a medical provider ($50) and filling a PrEP prescription ($50). At the 3-month follow-up assessment, participants who report they have not filled a prescription for PrEP are randomized a second time to either: 1) Switch to a second-stage intervention (i.e., MI + CM or CM + MI); or 2) Continue with assessments only. Outcomes for both responders and non-responders are reassessed at a 6-month follow-up. The primary outcome is documented evidence of filling a PrEP prescription. Self-reported, secondary outcomes include PrEP clinical evaluation by a medical provider, stimulant use, and condomless anal sex. Qualitative exit interviews are conducted with a sub-group of responders and non-responders to characterize their experiences with the MI and CM interventions.Discussion Implementation of this pilot SMART underscores the challenges in reaching SMM who use stimulants to optimize HIV prevention efforts such that approximately one in ten (104/1,060) eligible participants enrolled. However, 85% (70/82) of enrolled participants with non-reactive HIV results were randomized. Further research is needed to determine the effectiveness of telehealth MI and CM for supporting PrEP use in SMM who use stimulants.Trial Registration: This protocol was registered on clinicaltrials.gov (NCT04205487) on December 19, 2019.