bluuebunny/crossref_metadata_2025_split huggingface dataset:
King penguins adjust their fine-scale travelling and foraging behaviours to spatial and diel changes in feeding opportunities
Authors: Watanabe Hina , Shiomi Kozue , Sato Katsufumi , Takahashi Akinori , Handrich Yves , Bost Charles-André 
Published: January 2023

AbstractCentral place foragers such as pelagic seabirds often travel large distances to reach profitable foraging areas. King penguins (Aptenodytes patagonicus) are well known for their large-scale foraging movements to the productive Antarctic Polar Front, though their fine-scale travelling and foraging characteristics remain unclear. Here, we investigated the horizontal movements and foraging patterns of king penguins to understand their fine-scale movement decisions during distant foraging trips. We attached multi-channel data loggers that can record depth, speed, tri-axis acceleration, tri-axis magnetism, and environmental temperature of the penguins and obtained data (n = 8 birds) on their horizontal movement rates from reconstructed dive paths and their feeding attempts estimated from rapid changes in swim speed. During transit toward main foraging areas, penguins increased the time spent on shallow travelling dives (< 50 m) at night and around midday, and increased the time spent on deep foraging dives (≥ 50 m) during crepuscular hours. The horizontal movement rates during deep dives were negatively correlated with maximum dive depths, suggesting that foraging at greater depths is associated with a decreased horizontal travelling speed. Penguins concentrated their foraging efforts (more deep dives and higher rates of feeding attempts) at twilight during transit, when prey may be more accessible due to diel vertical migration, while they travelled rapidly at night and midday when prey may be difficult to detect and access. Such behavioural adjustments correspond to a movement strategy adopted by avian deep divers to travel long distances while feeding on prey exhibiting diel vertical migration.
Usefulness of nerve-sparing pedicled segmental latissimus dorsi muscle flap combined with lateral thoracic skin flap for partial volume reconstruction in laterally located breast cancer
Authors: Abdelmofeed Ayman M. , Fadey Mohammed A. , Seif Ola , Abdelhalim Mohamed H. , Younes Mohamed T. 
Published: January 2023

Abstract

Background
The latissimus dorsi muscle (LDM) is a flexible muscle that is frequently employed in various reconstructive operations. Breast-conserving surgery is widely acknowledged as an effective treatment for breast cancer, and the latissimus dorsi muscle flap is a straightforward, dependable technique for partial breast reconstruction.

Methods
A pedicled segmental latissimus dorsi muscle flap was employed in 20 patients with laterally situated breast cancer treated at our institution from January 2018 to December 2021. During a 6-month postoperative follow-up period, patients were polled on their overall satisfaction and cosmetic satisfaction. Plastic surgeons assessed the aesthetic and functional outcomes in terms of breast shape and symmetry, as well as muscular function.

Results
The mean operative time was 120 ± 35.2 min while the mean postoperative hospital stay was 2.5 days (range, 1.5–3 days). There were no donor site complications such as intraoperative bleeding, postoperative hematoma, or infection, and postoperative drain removal was done on average after 5 days. The average weight of specimens was 50–160 gm with a mean of 100 gm, and the locations of the masses were the upper lateral quadrant (n = 15), the lower lateral quadrant (n = 2), and the central lateral area (n = 3). Complications developed in 6 of the cases, hematoma in 2 cases, wound seroma developed in the donor site in 2 cases, and weakness in shoulder movement in 2 cases, and the majority of the patients were satisfied with their cosmetic outcomes. No tumor recurrence was reported.

Conclusion
Replacement of 20 to 40% of breast volume in the upper and the lower outer quadrants with a latissimus dorsi muscle flap as nerve-sparing pedicled segmental flap that can be harvested from the same axillary incision of lymphadenectomy is a good alternative reconstruction technique after partial mastectomy. This resulted in an acceptable postoperative scar, less pain, and early upper extremity movement, so this technique is considered a useful and reliable technique in correcting breast deformity after breast-conserving surgery, especially in laterally located breast cancer.

Level of evidence: Level IV, therapeutic study.
Biomarkers in osteoarthritis: current status and outlook — the FNIH Biomarkers Consortium PROGRESS OA study
Authors: Hunter David J. , Collins Jamie E. , Deveza Leticia , Hoffmann Steven C. , Kraus Virginia B. 
Published: January 2023

AbstractCurrently, no disease-modifying therapies are approved for osteoarthritis (OA) use. One obstacle to trial success in this field has been our existing endpoints’ limited validity and responsiveness. To overcome this impasse, the Foundation for the NIH OA Biomarkers Consortium is focused on investigating biomarkers for a prognostic context of use for subsequent qualification through regulatory agencies. This narrative review describes this activity and the work underway, focusing on the PROGRESS OA study.
Real-world multicentre cohort of first-line pembrolizumab alone or in combination with platinum-based chemotherapy in non-small cell lung cancer PD-L1 ≥ 50%
Authors: Pons-Tostivint E. , Hulo P. , Guardiolle V. , Bodot L. , Rabeau A. , Porte M. , Hiret S. , Demontrond P. , Curcio H. , Boudoussier A. , Veillon R. , Mayenga M. , Dumenil C. , Chatellier T. , Gourraud P. A. , Mazieres J. , Bennouna J. 
Published: January 2023

Abstract
Introduction
Pembrolizumab alone (IO-mono) or in combination with platinum-based chemotherapy (CT-IO) is first-line standard of care for advanced non-small cell lung cancer (NSCLC) patients with PD-L1 ≥ 50%. This retrospective multicentre study assessed real-world use and efficacy of both strategies.

Methods
Patients with advanced NSCLC PD-L1 ≥ 50% from eight hospitals who had received at least one cycle of IO-mono or CT-IO were included. Overall survival (OS) and real-word progression-free-survival were estimated using Kaplan–Meier methodology. Cox proportional hazards regression models were used to estimate hazard ratios (HRs) and 95% CIs, and a Cox model with inverse propensity treatment weighting was carried out.

Results
Among the 243 patients included, 141 (58%) received IO-mono and 102 (42%) CT-IO. Younger patients, those with symptomatic disease and brain metastases were more likely to be proposed CT-IO. With a median follow-up of 11.5 months (95% CI 10.4–13.3), median OS was not reached, but no difference was observed between groups (p = 0.51). Early deaths at 12 weeks were 11% (95% CI 4.6–16.9) and 15.2% (95% CI 9.0–20.9) in CT-IO and IO groups (p = 0.32). After adjustment for age, gender, performance status, histology, brain metastases, liver metastases and tobacco status, no statistically significant difference was found for OS between groups, neither in the multivariate adjusted model [HR 1.07 (95% CI 0.61–1.86), p = 0.8] nor in propensity adjusted analysis [HR 0.99 (95% CI 0.60–1.65), p = 0.99]. Male gender (HR 2.01, p = 0.01) and PS ≥ 2 (HR 3.28, p < 0.001) were found to be negative independent predictive factors for OS.

Conclusion
Younger patients, those with symptomatic disease and brain metastases were more likely to be proposed CT-IO. However, sparing the chemotherapy in first-line does not appear to impact survival outcomes, even regarding early deaths.
FAIRagro: Ein Konsortium in der Nationalen Forschungsdateninfrastruktur (NFDI) für Forschungsdaten in der Agrosystemforschung
Authors: Specka Xenia , Martini Daniel , Weiland Claus , Arend Daniel , Asseng Senthold , Boehm Franziska , Feike Til , Fluck Juliane , Gackstetter David , Gonzales-Mellado Aida , Hartmann Thomas , Haunert Jan-Henrik , Hoedt Florian , Hoffmann Carsten , König Patrick , Lange Matthias , Lesch Stephan , Lindstädt Birte , Lischeid Gunnar , Möller Markus , Rascher Uwe , Reif Jochen Christoph , Schmalzl Markus , Senft Matthias , Stahl Ulrike , Svoboda Nikolai , Usadel Björn , Webber Heidi , Ewert Frank 
Published: January 2023

ZusammenfassungFAIRagro ist ein Konsortium in der Nationalen Forschungsdateninfrastruktur (NFDI) in Deutschland um Forschungsdaten der Agrosystemforschung FAIR – d. h. auffindbar (F), zugänglich (A), interoperabel (I) und für andere Forschende domänenübergreifend nachnutzbar (R) zu machen. In der deutschen Forschungslandschaft rund um nachhaltige Agrosysteme werden heterogene Forschungsdaten erhoben und nur zum Teil in existierenden Forschungsdatenrepositorien veröffentlicht. Das Spektrum der Datenformate erstreckt sich beispielsweise von Laborergebnissen, über Satellitenbilder bis hin zu qualitativen Interviews mit Landwirt:innen. Um diese Daten zukünftig für Forschende verschiedener Disziplinen besser auffindbar und nachnutzbar zu machen, wird FAIRagro eine Forschungsdateninfrastruktur (FDI) für die Agrosystemforschung einrichten, in der disziplinäre Dateninfrastrukturen miteinander verknüpft werden. Spezifische Herausforderungen im Forschungsdatenmanagement (FDM) fachlicher Disziplinen wie Pflanzenzüchtung, integrierter Pflanzenschutz oder Agrarrobotik werden als Use Cases in FAIRagro adressiert und für diese Lösungen entwickelt. Darüber hinaus wird FAIRagro ein Netzwerk aus direkten Ansprechpersonen für Fragen zum Forschungsdatenmanagement in der Agrosystem-Community bereitstellen. In Übereinstimmung mit den Zielsetzungen der NFDI und der European Open Science Cloud ist FAIRagro aktiv an der konzeptionellen Implementierung eines interoperablen Datenraums beteiligt.
Dark papillary muscles sign: a novel prognostic marker for cardiac magnetic resonance
Authors: Aquaro Giovanni Donato , De Gori Carmelo , Grilli Giulia , Licordari Roberto , Barison Andrea , Todiere Giancarlo , Ianni Umberto , Parollo Matteo , Grigoratos Crysanthos , Restivo Luca , De Luca Antonio , Faggioni Lorenzo , Cioni Dania , Sinagra Gianfranco , Di Bella Gianluca , Neri Emanuele 
Published: January 2023

Abstract
Objectives
The prognostic role of left ventricular (LV) papillary muscle abnormalities in patients with preserved LV systolic ejection fraction (LVEF) is unknown. We sought to evaluate the prognosis role of LV papillary muscle abnormalities by CMR in patients with ventricular arrhythmias, preserved LVEF with no cardiac disease.

Methods
A total of 391 patients with > 500/24 h premature ventricular complexes and/or with non-sustained ventricular tachycardia (NSVT), preserved LVEF, and no cardiac disease were enrolled. Different features of LV papillary muscles were considered: supernumerary muscles, papillary thickness, the attachment, late gadolinium enhancement (LGE). Dark-Paps was defined as end-systolic signal hypointensity of both papillary muscles in early post-contrast cine CMR images. Mitral valve prolapse, mitral annular disjunction (MAD), and myocardial LGE were considered.

Results
Dark-Paps was found in 79 (20%) patients and was more frequent in females. It was associated with higher prevalence of mitral valve prolapse and MAD. During a median follow-up of 2534 days, 22 hard cardiac events occurred. At Kaplan-Meier curve analysis, patients with Dark-Paps were at higher risk of events than those without (p < 0.0001). Dark-Paps was significantly associated with hard cardiac events in all the multivariate models. Dark-Paps improved prognostic estimation when added to NSVT (p = 0.0006), to LGE (p = 0.005) and to a model including NSVT+LGE (p = 0.014). Dark-Paps allowed a significant net reclassification when added to NSVT (NRI 0.30, p = 0.03), to LGE (NRI 0.25, p = 0.04), and to NSVT + LGE (NRI 0.32, p = 0.02).

Conclusions
In LV papillary muscles, Dark-Paps is a novel prognostic marker in patients with ventricular arrhythmias and preserved ejection fraction.

Key Points
• Papillary muscle abnormalities are seen in patients with ventricular arrhythmias and preserved left ventricular ejection fraction.
• Early post-contrast hypointensity of papillary muscles in end-systolic cine images (Dark-Paps) is a novel prognostic marker in patients with ventricular arrhythmias and preserved ejection fraction.
• Dark-Paps had an additive prognostic role over late gadolinium enhancement and non-sustained ventricular tachycardia.
Shear layers in two-stage compound channels investigated with LS-PIV
Authors: Dupuis Victor , Schraen Laura , Eiff Olivier 
Published: January 2023

AbstractFlow experiments are conducted in a two-stage compound open-channel, with varying intensity of the velocity difference between the main channel (deep part) and the floodplain (shallower part), using a large-scale free surface PIV technique (LS-PIV). For all investigated flows, a shear layer develops at the interface between main channel and floodplain, characterised by a peak of turbulent shear stress. Yet, two different kinds of shear layer could be identified. The first kind is characterised by the presence of large-scale quasi-periodic structures of Kelvin-Helmholtz type which are growing in downstream direction, whereas the second kind is characterised by smaller-scale vortical structures without quasi-periodicity and which do not grow in downstream direction. The shear parameter$$\lambda =(U_2-U_1)/(U_2+U_1)$$λ=(U2-U1)/(U2+U1), where$$U_1$$U1and$$U_2$$U2are defined as the velocities outside the shear layer, is identified as a key parameter to distinguish between these two types of shear layers, supporting a result from Proust et al. (Water Resour Res 53: 3387–3406, 2017). A physical interpretation of the$$\lambda$$λ-criterion is proposed, based on the inhibiting effect of ambient turbulence (the turbulence level outside the shear layer) on the emergence of Kelvin-Helmholtz structures. Accordingly, the threshold value of$$\lambda$$λ, above which large-scale structures can develop, is dependent on the level of the ambient turbulence. Despite their very different behaviours, the two types of shear layer have the same efficiency to generate turbulent shear stress for a given velocity difference across the shear layer, except for$$\lambda$$λ-values close to the threshold value.
Uncertainty and validation of unsteady pressure-sensitive paint measurements of acoustic fields under aero engine-like conditions
Authors: Goessling Jan , Fischer Felix , Seume Joerg R. , Hilfer Michael 
Published: January 2023

Abstract
Fast response pressure-sensitive paint (PSP) allows optical measurements of pressure fluctuations on a surface with high spatial and temporal resolution. This technique is evaluated for aeroacoustic measurements inside an aeroacoustic wind tunnel (AWT). The AWT is a test rig especially designed for investigating the excitation and propagation of sound under conditions typical for turbomachinery. The aim of this work is to compare the results of sound pressure measurements of tonal sound fields in a circular duct conducted with PSP and microphone arrays in order to assess the applicability of PSP in turbomachinery acoustics applications. A data analysis process is presented, which projects the camera image of the PSP data onto a given surface. To analyze the spatial pressure fluctuations, the PSP data are transformed in the frequency domain using pixel-wise fast Fourier transform. Measurements with a mean Mach number up to 0.109 and 5 kHz excitation frequency are conducted. An acoustic mode generator is used to excite the sound field with specific circumferential mode order. The pressure fluctuations obtained with the PSP measurement visualize the measured acoustic field well and allow early interpretation. The pressures of PSP and microphones are in good agreement; for example, the maximum detected deviation in pressure at 2700 Hz is 30 Pa. A preview on using radial mode analysis to decompose the acoustic field, measured by PSP, into acoustic modes is provided. The results are confirmed by a decomposition using conventional arrays of flush-mounted microphones.

Graphical Abstract
Impact-driven cavitation bubble dynamics
Authors: Bao Hengzhu , Reuter Fabian , Zhang Hongchao , Lu Jian , Ohl Claus-Dieter 
Published: January 2023

AbstractThe dynamics of a single cavitation bubble exposed to a transient acceleration is studied experimentally. A single cavitation bubble is seeded with a pulsed laser in a free-falling and impacting water-filled test tube. After impact, a pressure wave containing compression and rarefaction phases is generated and interacts with the bubble. The bubble dynamics is studied with high-speed imaging and compared to numerical simulations using the Keller–Miksis model. The timing of bubble seeding with respect to the pressure wave is varied, and a regime of enhanced collapse strength is found.
Symptoms of older orthopedic and rheumatic patients
Authors: Schiek Susanne , Hintzer Katharina , Dahley Carolin , Wernecke Kathrin , Feindt Birgit , Baerwald Christoph , Spiegl Ulrich J. A. , Bertsche Thilo 
Published: January 2023

Abstract
Background
In older multimorbid orthopedic and rheumatic patients, data on symptoms besides pain or reduced mobility are rarely published.

Objective
We investigated patients’ perspectives on their symptoms after hospital discharge.

Material and methods
Orthopedic and rheumatic patients aged over 70 years were asked via telephone interviews about (i) their symptoms, (ii) communication, (iii) treatment, and (iv) support.

Results
(i) The 60 participants (35 women and 25 men) reported a median of 6 (min-max: 1–14) different symptoms, of which 86% (356 of 415) had existed before hospitalization, (ii) patients did not communicate 28% (117) of symptoms to either healthcare professionals, family or friends and (iii) 52 (87%) patients desired improvement. Of the 280 most impairing symptoms, 19% (52) were not treated at all. (iv) Almost all patients (59; 98%) considered it easy to obtain support.

Conclusion
Remarkably, many symptoms were not communicated or treated despite the patients having been hospitalized.
Effects of anti-inflammatory dietary patterns on non-alcoholic fatty liver disease: a systematic literature review
Authors: Abdallah Jayden , Assaf Samantha , Das Arpita , Hirani Vasant 
Published: January 2023

Abstract
Purpose
Non-alcoholic fatty liver disease (NAFLD) is the leading chronic hepatic condition. Low-grade chronic inflammation contributes to disease progression. Diet has protective effects on hepatic health and inflammatory pathways. The purpose of this review is to systematically review and describe the effects of anti-inflammatory dietary patterns on NAFLD.

Methods
The Cochrane CENTRAL Library, Cumulative Index of Nursing and Allied Health Literature, Embase, MEDLINE and Web of Science databases were searched. A total of 252 records were identified, 7 of which were included in this review. The revised Cochrane risk-of-bias tool was used to conduct a quality assessment for randomised trials. Certainty of evidence was assessed using the grading of recommendations, assessment, development, and evaluation tool.

Results
Of the 7 included studies, 6 were classified as low risk of bias and studies ranged from high to very low certainty of evidence. In the randomised-controlled studies systematically reviewed, either adherence to the Mediterranean, DASH, or FLiO diet was studied, against usual care or energy matched controls, with a total of 255 participants. Anti-inflammatory dietary pattern adherence significantly reduced the severity of most hepatic and inflammatory markers, and secondary outcomes. A minority of outcomes were improved significantly more than controls.

Conclusion
Anti-inflammatory dietary patterns showed benefits to NAFLD risk factors, severity markers and inflammatory markers compared to the control diet. It is unclear whether reductions in the evaluated parameters are related solely to the anti-inflammatory diet or weight loss resulting from caloric restriction, as improvements in control groups were also evidenced. Current limited body of evidence indicates need for further research including isocaloric dietary patterns, longer interventions, measures of inflammatory markers, and studies including normal-weight subjects to confirm findings at higher certainty.

PROSPERO Registration
CRD42021269382.
Performance with a new bone conduction implant audio processor in patients with single-sided deafness
Authors: Wimmer Wilhelm , Zbinden Michael , Gawliczek Tom , Huber Alexander , Caversaccio Marco , Kompis Martin 
Published: January 2023

Abstract
Purpose
The SAMBA 2 BB audio processor for the BONEBRIDGE bone conduction implant features a new automatic listening environment detection to focus on target speech and to reduce interfering speech and background noises. The aim of this study was to evaluate the audiological benefit of the SAMBA 2 BB (AP2) and to compare it with its predecessor SAMBA BB (AP1).

Methods
Prospective within-subject comparison study. We compared the aided sound field hearing thresholds, speech understanding in quiet (Freiburg monosyllables), and speech understanding in noise (Oldenburg sentence test) with the AP1 and AP2. Each audio processor was worn for 2 weeks before assessment and seven users with single-sided sensorineural deafness (SSD) participated in the study. For speech understanding in noise, two complex noise scenarios with multiple noise sources including single talker interfering speech were used. The first scenario included speech presented from the front (S0NMIX), while in the second scenario speech was presented from the side of the implanted ear (SIPSINMIX). In addition, subjective evaluation using the SSQ12, APSQ, and the BBSS questionnaires was performed.

Results
We found improved speech understanding in quiet with the AP2 compared to the AP1 aided condition (on average + 17%, p = 0.007). In both noise scenarios, the AP2 lead to improved speech reception thresholds by 1.2 dB (S0NMIX, p = 0.032) and 2.1 dB (SIPSINMIX, p = 0.048) compared to the AP1. The questionnaires revealed no statistically significant differences, except an improved APSQ usability score with the AP2.

Conclusion
Clinicians can expect that patients with SSD will benefit from the SAMBA 2 BB by improved speech understanding in both quiet and in complex noise scenarios, when compared to the older SAMBA BB.
Surgical therapy of celiac axis and superior mesenteric artery syndrome
Authors: Jonas J. P. , Rössler F. , Ghafoor S. , Kobe A. , Pfammatter T. , Schlag C. , Gutschow C. A. , Petrowsky H. , Müller P. C. , Oberkofler C. E. 
Published: January 2023

Abstract

Introduction
Compression syndromes of the celiac artery (CAS) or superior mesenteric artery (SMAS) are rare conditions that are difficult to diagnose; optimal treatment remains complex, and symptoms often persist after surgery. We aim to review the literature on surgical treatment and postoperative outcome in CAS and SMAS syndrome.

Methods
A systematic literature review of medical literature databases on the surgical treatment of CAS and SMAS syndrome was performed from 2000 to 2022. Articles were included according to PROSPERO guidelines. The primary endpoint was the failure-to-treat rate, defined as persistence of symptoms at first follow-up.

Results
Twenty-three studies on CAS (n = 548) and 11 on SMAS (n = 168) undergoing surgery were included. Failure-to-treat rate was 28% for CAS and 21% for SMAS. Intraoperative blood loss was 95 ml (0–217) and 31 ml (21–50), respectively, and conversion rate was 4% in CAS patients and 0% for SMAS. Major postoperative morbidity was 2% for each group, and mortality was described in 0% of CAS and 0.4% of SMAS patients. Median length of stay was 3 days (1–12) for CAS and 5 days (1–10) for SMAS patients. Consequently, 47% of CAS and 5% of SMAS patients underwent subsequent interventions for persisting symptoms.

Conclusion
Failure of surgical treatment was observed in up to every forth patient with a high rate of subsequent interventions. A thorough preoperative work-up with a careful patient selection is of paramount importance. Nevertheless, the surgical procedure was associated with a beneficial risk profile and can be performed minimally invasive.