bluuebunny/crossref_metadata_2025_split huggingface dataset:
Motivating factors and barriers to help-seeking for casino gamblers: results from a survey in Swiss casinos
Authors: Lischer Suzanne , Schwarz Jürg , Wallimann Hannes , Jeannot Emilien , Mathys Jacqueline 
Published: May 2023

IntroductionGambling can have serious consequences for many aspects of a person’s life. Yet relatively few people with gambling problems seek help. This study examines the extent to which exclusion from casino venues among other factors may act as a motivator for further help-seeking among casino gamblers (both landbased and remote) with at-risk or disordered gambling behavior. In addition, the barriers that prevent gamblers from accepting help are examined.MethodsGamblers from Swiss casinos completed a written questionnaire twice, at 6-month intervals. The questions included whether they had sought help in the past 6 months.ResultsFor those with a SOGS-R rating of 1 or over (n = 173) at the second survey point, a difference in help-seeking was found between the excluded and non-excluded gamblers (p &lt; .001), suggesting that exclusion may be a motivator for help-seeking. Reported differences in levels of debt (p = .006), recognition of gambling problems (p = .010) and severity of gambling-related problems (p = .004) can be taken to suggest that other motivating factors may also influence help-seeking behavior. With regard to the support sought, the most frequently used forms of support were specialized addiction counseling centers (39.5%), followed by self-help groups (21.1%) and remote counseling centers (10.5%). In terms of barriers, reasons relating to attitude, such as denial, appear to pose greater barriers than treatment-related concerns.DiscussionFrom a public health perspective, an overarching strategy is required to increase the share of help-seekers among casino gamblers through targeted measures.
Altered gut microbiota profile in patients with perimenopausal panic disorder
Authors: Lin Shen , Wang Hongjin , Qiu Jingjing , Li Minghong , Gao Ebin , Wu Xiaofeng , Xu Yunxiang , Chen Guizhen 
Published: May 2023

IntroductionFemales in the perimenopausal period are susceptible to mood disorders. Perimenopausal panic disorder (PPD) is characterized by repeated and unpredictable panic attacks during perimenopause, and it impacts the patient's physical and mental health and social function. Pharmacotherapy is limited in the clinic, and its pathological mechanism is unclear. Recent studies have demonstrated that gut microbiota is strongly linked to emotion; however, the relation between PPD and microbiota is limitedly known.MethodsThis study aimed to discover specific microbiota in PPD patients and the intrinsic connection between them. Gut microbiota was analyzed in PPD patients (n = 40) and healthy controls (n = 40) by 16S rRNA sequencing.ResultsThe results showed reduced α-diversity (richness) in the gut microbiota of PPD patients. β-diversity indicated that PPD and healthy controls had different intestinal microbiota compositions. At the genus level, 30 species of microbiota abundance had significantly different between the PPD and healthy controls. In addition, HAMA, PDSS, and PASS scales were collected in two groups. It was found that Bacteroides and Alistipes were positively correlated with PASS, PDSS, and HAMA.DiscussionBacteroides and Alistipes dysbiosis dominate imbalanced microbiota in PPD patients. This microbial alteration may be a potential pathogenesis and physio-pathological feature of PPD. The distinct gut microbiota can be a potential diagnostic marker and a new therapeutic target for PPD.
Usability and acceptability testing of a Plan of Safe Care in a mobile health platform
Authors: Isaacs Krystyna R. , Bajracharya Elina , Taylor Shantae , Chang Katie , Washio Yukiko , Parker Trenee , Paul David A. , Ma Tony X. 
Published: May 2023

PurposeWomen who are pregnant or parenting while recovering from substance use disorder (SUD) are at risk for insufficient recovery support. With the federal mandate, implementation has been left to each state for the Plan of Safe Care (POSC), leading to challenges in providing comprehensive care coordination and meeting federal reporting requirements.MethodsThis research tests the usability and acceptability of a POSC platform, called SAFE4BOTH, which combines a mobile health (mHealth) app for use by mothers with substance use disorder (MSUD) with a web-based case management system for use by stakeholders to reduce the issue of fragmented postnatal maternal and infant care. The platform was designed to enable access to services, improve reporting task workflow, and assist in improving interactions between mothers and service providers.After applying a user-centered design approach, the usability and acceptability of the SAFE4BOTH platform were evaluated using focus groups, interviews, and a System Usability Scale (SUS). The evaluation involved four staff members from a Medication for Addiction Treatment clinic (comprising of three case management workers and one peer counselor), four state employees of the Delaware Division of Family Services, and 20 mothers with MSUD who had delivered infants in need of a POSC.Features tested in the SAFE4BOTH platform included a secure, web-based POSC, a contingency management-based reward system, a micro-learning library, a resources locator, a chat messaging and videoconferencing system, a directory for contact management, a QR code reader, use of an appointment compliance system engaging geofencing, and an enhanced calendar. Family services and treatment center staff accessed SAFE4BOTH from their laptops or tablets, and MSUD accessed SAFE4BOTH from their phones.ResultsFamily services staff, treatment center staff, and MSUD participants rated SAFE4BOTH as usable and acceptable with average System Usability Scale scores of 68.1 (SD 8.5), 92.5 (SD 11.73), and 78.4 (SD 12.5) (respectively).ConclusionThe platform was judged both usable and acceptable by all three target populations (family services staff, treatment center staff, and MSUD). Further studies are planned to explore the efficacy of longitudinally supporting the mother’s recovery and the infant’s healthy development.
Association between metabolically healthy obesity and kidney stones: results from the 2011–2018 National Health and Nutrition Examination Survey
Authors: Chen Weinan , Man Sailimai , Hong Yang , Kadeerhan Gaohaer , Chen Liang , Xu Qingquan , Xiong Liulin , Xu Tao , Wang Bo , Huang Xiaobo 
Published: May 2023

IntroductionThe risk of kidney stones in metabolically healthy obesity (MHO) individuals is largely unexplored. This study using percent body fat (%BF) to categorize obesity, to investigate the association between MHO as well as other metabolic syndrome-obesity combined phenotypes and kidney stones in a national representative population.Materials and methodsThis cross-sectional study included 4,287 participants in the National Health and Nutrition Examination Survey from 2011 to 2018. Metabolically healthy status was defined as not having any component of metabolic syndrome or insulin resistance. Obesity was identified by %BF, which was measured and assessed by dual-energy x-ray absorptiometry (DXA) scan. Participants were cross-classified by metabolic health and obesity status. The outcome was self-report kidney stones. Multivariable logistic regression model was used to examine the association between MHO and kidney stones.ResultsA total of 358 participants had kidney stones [weighted prevalence (SE): 8.61% (0.56%)]. The weighted prevalence (SE) of kidney stones in MHN, MHOW, and MHO groups was 3.13% (1.10%), 4.97% (1.36%), and 8.55% (2.09%), respectively. After adjusting for age, sex, race and ethnicity, education level, smoking status, alcohol consumption, physical activity, daily water intake, CKD stage 3–5, and hyperuricemia, MHO individuals (OR: 2.90, 95% CI: 1.18, 7.0) had a significantly higher risk of kidney stones than those with metabolically healthy normal weight. In metabolically healthy participants, a 5% increment in %BF was associated with a significantly higher risk of kidney stones (OR: 1.60, 95% CI: 1.20, 2.14). Furthermore, a nonlinear dose–response relationship between %BF and the kidney stones was observed in metabolically healthy participants (P for non-linearity = 0.046).ConclusionUsing %BF to define obesity, MHO phenotype was significantly associated with higher risks of kidney stones, suggesting that obesity can independently contribute to kidney stones in the absence of metabolic abnormalities and insulin resistance. Regarding kidney stones prevention, MHO individuals might still benefit from lifestyle interventions aimed at healthy body composition maintenance.
Critical air pollutant assessments and health effects attributed to PM2.5 during and after COVID-19 lockdowns in Iran: application of AirQ+ models
Authors: Ghobakhloo Safiye , Khoshakhlagh Amir Hossein , Mostafaii Gholam Reza , Chuang Kai-Jen , Gruszecka-Kosowska Agnieszka , Hosseinnia Pariya 
Published: May 2023

ObjectivesThe aim of this study was to evaluate changes in air quality index (AQI) values before, during, and after lockdown, as well as to evaluate the number of hospitalizations due to respiratory and cardiovascular diseases attributed to atmospheric PM2.5 pollution in Semnan, Iran in the period from 2019 to 2021 during the COVID-19 pandemic.MethodsDaily air quality records were obtained from the global air quality index project and the US Environmental Protection Administration (EPA). In this research, the AirQ+ model was used to quantify health consequences attributed to particulate matter with an aerodynamic diameter of &lt;2.5 μm (PM2.5).ResultsThe results of this study showed positive correlations between air pollution levels and reductions in pollutant levels during and after the lockdown. PM2.5 was the critical pollutant for most days of the year, as its AQI was the highest among the four investigated pollutants on most days. Mortality rates from chronic obstructive pulmonary disease (COPD) attributed to PM2.5 in 2019–2021 were 25.18% in 2019, 22.55% in 2020, and 22.12% in 2021. Mortality rates and hospital admissions due to cardiovascular and respiratory diseases decreased during the lockdown. The results showed a significant decrease in the percentage of days with unhealthy air quality in short-term lockdowns in Semnan, Iran with moderate air pollution. Natural mortality (due to all-natural causes) and other mortalities related to COPD, ischemic heart disease (IHD), lung cancer (LC), and stroke attributed to PM2.5 in 2019–2021 decreased.ConclusionOur results support the general finding that anthropogenic activities cause significant health threats, which were paradoxically revealed during a global health crisis/challenge.
Understanding the system dynamics of obesity-related behaviours in 10- to 14-year-old adolescents in Amsterdam from a multi-actor perspective
Authors: Luna Pinzon Angie , Stronks Karien , Emke Helga , van den Eynde Emma , Altenburg Teatske , Dijkstra S. Coosje , Renders Carry M. , Hermans Roel , Busch Vincent , Chinapaw Mai J. M. , Kremers Stef P. J. , Waterlander Wilma 
Published: May 2023

Introduction and MethodsTo develop an understanding of the dynamics driving obesity-related behaviours in adolescents, we conducted systems-based analysis on a causal loop diagram (CLD) created from a multi-actor perspective, including academic researchers, adolescents and local stakeholders.ResultsThe CLD contained 121 factors and 31 feedback loops. We identified six subsystems with their goals: (1) interaction between adolescents and the food environment, with profit maximisation as goal, (2) interaction between adolescents and the physical activity environment, with utility maximisation of outdoor spaces as goal, (3) interaction between adolescents and the online environment, with profit maximisation from technology use as goal, (4) interaction between adolescents, parenting and the wider socioeconomic environment, with a goal focused on individual parental responsibility, (5) interaction between healthcare professionals and families, with the goal resulting in treating obesity as an isolated problem, and (6) transition from childhood to adolescence, with the goal centring around adolescents’ susceptibility to an environment that stimulates obesity-related behaviours.DiscussionAnalysis showed that inclusion of the researchers’ and stakeholders’ perspectives contributed to an understanding of how the system structure of an environment works. Integration of the adolescents’ perspective enriched insights on how adolescents interact with that environment. The analysis further showed that the dynamics driving obesity-related behaviours are geared towards further reinforcing such behaviours.
Patient characteristics, symptoms, and urodynamic parameters associated with detrusor contraction duration in women
Authors: Wang Connie N. , Ha Albert , Chung Doreen E. 
Published: May 2023

BackgroundThere is a lack of understanding of the clinical significance of detrusor contraction duration (DCD) measured on urodynamic studies (UDS). We aimed to identify patient characteristics, presenting symptoms and urodynamic parameters associated with DCD in women.MethodsUsing a single-institution database of UDS (2015-2019), 405 female patients with measurable detrusor contractions were identified. Baseline characteristics, presenting symptoms and UDS parameters were analyzed. Bladder outlet obstruction (BOO) was characterized using the Blaivas-Groutz nomogram. Wilcox Rank Sum Tests were used for descriptive statistics, and a univariable generalized linear model conforming to a gamma distribution was used.ResultsMedian age was 65 years (IQR 52-75), BMI was 27.5 kg/m2 (IQR 23.9-31.1) and DCD was 90 seconds (IQR 57-124). On univariable analysis, degenerative disc disease (β = -17.9, p = 0.02), pelvic radiation (β = -31.91, p = 0.04), and stress incontinence (β = -14.11, p = 0.03) were associated with reduced DCD. Black race was associated with longer DCD (β = 22.92, p = 0.01). Analysis of UDS parameters revealed a significant increase in DCD per unit increase of bladder capacity (β = 0.08, p&lt;0.001), detrusor pressure (Pdet) at maximum flow (Qmax) (β = 0.96, p&lt;0.001), and maximum Pdet (β = 1.2, p&lt;0.001). In contrast, a significant decrease in DCD was noted per unit increase in Qmax (β = -1.43, p&lt;0.001). Finally, mild (β = 34.4, p&lt;0.001), moderate (β = 72.52, p&lt;0.001), and severe (β = 64.6, p&lt;0.001) BOO were all associated with increased DCD.ConclusionsMedian DCD in women is 90 seconds. Longer DCD is associated with greater degree of BOO, higher maximum Pdet, Pdet at Qmax, and bladder capacity. Disc disease, irradiation and stress incontinence are associated with reduced DCD. Further studies are needed to evaluate the predictive value of DCD in women.
Direct dotterising or angioplasty of acute stroke due to tandem atherosclerotic occlusions
Authors: Yeo Leonard L. L. , Simonato Davide , Bhogal Pervinder , Gopinathan Anil , Cunli Yang , Ong Samuel W. Q. , Jing Mingxue , Tan Benjamin Y. Q. , Sia Ching-Hui , Jia Tom , Cester Giacomo , Gabrieli Joseph-Domenico , Andersson Tommy 
Published: May 2023

BackgroundTandem occlusions cause 10–15% of LVO acute ischemic strokes but are difficult to treat endovascularly and frequently excluded from clinical trials. The optimum endovascular method is still debated, however going directly through the carotid occlusion can speed up the procedure and reduce procedural risk by eliminating an exchange maneuver.MethodUsing retrospective data from three centers, we compared treating atherosclerotic tandem occlusions using a 0.035'-guidewire and direct dotterisation or angioplasty with a peripheral vascular balloon suitable for the wire, vs. the usual technique of an 0.014'wire. We compared the successful recanalization (mTICI 2b-3) rates, 90 days' functional outcomes (mRS 0–2), and puncture-to-recanalization times between both procedures.ResultsForty-two consecutive patients with atherosclerotic tandem occlusions were included; 25 were treated with the 0.014'wire technique and 17 with the 0.035'-guidewire and direct dotterisation or angioplasty with a peripheral vascular balloon technique. The direct technique achieved a higher rate of successful recanalization (100 vs. 72%, P = 0.018), better functional outcome (88.4 vs. 48.0%, P = 0.044), and faster procedure times (mean 65.1 mins vs. 114.8 mins, P &lt; 0.001). The number of attempts was similar between both groups (median 2 vs 3 attempts, P = 0.101). There was no significant difference in the complication rate between both groups (5.9 vs. 12.0%, P = 0.462).ConclusionCompared to previous endovascular techniques for treating atherosclerotic tandem occlusions, the direct technique using standard 0.035' guidewires and dotterisation or a peripheral vascular balloon is significantly faster with better outcomes. However, this will require further external validation in larger cohorts.
A novel Laennec's capsule tunnel approach for pure laparoscopic left hemihepatectomy: a propensity score matching study
Authors: Lai Jianlin , Wu Junyi , Bai Yannan , Tian Yifeng , Wang Yaodong , Qiu Funan 
Published: May 2023

BackgroundWith the development of laparoscopic hepatectomy, there are different surgical approaches and pedicle anatomical methods for laparoscopic left hepatectomy. Combined with our practical experience, we proposed a method of transhepatic Laennec membrane tunnel for laparoscopic left hemihepatectomy (LT-LLH) and investigated the feasibility by comparison with the extrahepatic Glissonian approach for laparoscopic left hemihepatectomy (GA-LLH).Patients and methodsThe data of patients who underwent laparoscopic left hepatectomy in the Department of Hepatobiliary Pancreatic surgery of Fujian Provincial Hospital from December 2019 to March 2022 were analyzed retrospectively. Among them, 45 cases underwent laparoscopic left hemihepatectomy with an extrahepatic Glissonian approach, and 38 cases underwent laparoscopic left hemihepatectomy via transhepatic Laennec membrane tunnel approach. A 1:1 propensity score matching (PSM) method was performed to compare the perioperative indexes and long-term tumor prognosis between the two groups.ResultsAfter 1:1 PSM, 33 patients in each group were selected for further analysis. Compared with the GA-LLH group, the operation time of the LT-LLH group was shorter. There was no significant difference in the incidence of total complications between the two groups. Moreover, no statistical differences were found in disease-free survival and overall survival between the two groups.ConclusionIt is safe, faster, and convenient for selective appropriate cases to carry out laparoscopic left hemihepatectomy through the hepatic Laennec membrane tunnel, which is suitable for clinical promotion.
Abundance of Non-Native Birds in the City: Spatial Variation and Relationship with Socioeconomics in a South American City
Authors: Silva-Ortega Macarena , Muñoz-Pacheco Catalina B. , Villaseñor Nélida R. 
Published: May 2023

Cities commonly support a high abundance of non-native species that can affect both wildlife and human health; however, their distribution across the urban environment and their relationship with socioeconomics are not well documented. Here, we map the abundance of three non-native birds in a Latin American city—domestic pigeon (Columba livia f. domestica), house sparrow (Passer domesticus), and monk parakeet (Myiopsitta monachus)—and investigate the effect of socioeconomics on their abundance. We found that C. livia f. domestica exhibited a random distribution of abundance across the city but reached its greatest abundance in low-income areas. P. domesticus exhibited an aggregated distribution of abundance, being most abundant in the southern and western areas of the city and in low-income areas. M. monachus exhibited an aggregated distribution of abundance, being most abundant in the northeastern part of the city and reaching its greatest abundance in high-income areas. Low-income areas likely provide high abundance of food, shelter, and nesting sites for both C. livia f. domestica and P. domesticus, whereas high income areas have greater tree cover and larger trees in which M. monachus can build communal nests. Our study finds that the abundance of non-native birds varies across the city and between socioeconomic groups; therefore, targeted management is needed in different city zones to limit negative effects on native species and prevent zoonotic diseases.
X-Ray Endovascular Evaluation of the Effectiveness of Pharmacological Reperfusion in Acute Coronary Syndrome with ST Segment Elevation
Authors: Осипенко Д.В. , Гороховский С.Ю. , Легеза Н.В. , Гончарова Л.В. , Налетько А.Н. , Салихова П.О. 
Published: May 2023

Цель. Оценить число ангиографически подтвержденных реваскуляризаций инфаркт-связанной коронарной артерии у пациентов после фармакологической реперфузии при остром коронарном синдроме с подъемом сегмента ST. Материалы и методы. Произведен анализ карт 194 пациентов, которые были переведены в Гомельский областной клинический кардиологический центр (ЧКВ-центр) из медицинских стационаров города Гомеля и Гомельской области для проведения чрескожного коронарного вмешательства после фармакологической реперфузии миокарда при остром коронарном синдроме с подъемом сегмента ST. Критерием эффективности фармакологической реваскуляризации считалось наличие в инфарктсвязанной артерии коронарного кровотока 3 градации по шкале TIMI (Thrombolysis in Myoсardial Infarction). Результаты. При анализе коронароангиографии (КАГ) получены следующие результаты: кровоток TIMI 0 в инфаркт-связанной артерии отмечался у 45 (23,2 %) пациентов, кровоток TIMI 1 – у 6 (3,1%), TIMI 2 – 11 (5,7%), TIMI 3 – 129 (66,5%). В 3 (1,5%) случаях КАГ не была проведена из-за смерти пациентов. У пациентов с ангиографически эффективной тромболитической терапией (ТЛТ) выявлена достоверно бóльшая фракция выброса левого желудочка в сравнении с пациентами без признаков реканализации коронарной артерии. Выводы. Число ангиографически подтвержденных реваскуляризаций коронарной артерии у пациентов после фармакологической реперфузии при остром коронарном синдроме с подъемом сегмента ST составило 129 (66,5%) из 194 случаев. Наше исследование продемонстрировало достоверное снижение фракции выброса левого желудочка в группе пациентов с ангиографически неэффективной ТЛТ в сравнении с группой пациентов с ангиографически восстановленным кровотоком.
Purpose. To estimate the effectiveness of pharmacological reperfusion in STEMI patients proved by angiographically confirmed blood flow restoration in target coronary artery. Materials and methods. The analysis includes 194 medical records of STEMI patients who were transferred to Gomel Regional Clinical Cardiological Center (PCI-center) from Gomel region hospitals after clinically successful thrombolysis. Coronary angiography and PCI if eligible was performed to all patients after pharmacological treatment within 3 to 24 hours. Results. After analysis of coronary angiography results the following results were obtained: TIMI-0 blood flow in the infarct-related artery was observed in 45 (23.2%) patients, TIMI-1 blood flow in 6 (3.1%) patients, TIMI-2 – 11 (5.7%), TIMI-3 – 129 (66.5%), irrespectively of choice of thrombolysis agent. Conclusions. Amount of angiographycally clarified cases of successful thrombolysis in target vessel counted 129 (66.5%) out of 194 cases. The results show necessity to transfer a patient to PCI-center as soon as possible from the moment of thrombolysis.