bluuebunny/crossref_metadata_2025_split huggingface dataset:
High-Quality Chromosome-Level De Novo Assembly of the Trifolium repens
Authors: Wang Hongjie , Wu Yongqiang , He Yong , Li Guoyu , Ma Lichao , Li Shuo , Huang Jianwei , Yang Guofeng 
Published: March 2023

Abstract
Background: White clover (Trifolium repens L.), an excellent perennial legume forage, is a heterotetraploid native to southeastern Europe and southern Asia. It has high feeding, ecological, genetic breeding, and medicinal values and exhibits excellent resistance to cold, drought, trample, and weed infestation. Thus, white clover is widely planted in Europe, America, and China. However, the lack of reference genome limits white clover breeding and cultivation. This study generated a white clover de novo genome assembly at the chromosomal level and annotated its components.
Results: The PacBio third-generation Hi-Fi assembly and sequencing methods were used to generate a 1096 Mb genome size of T. repens, with contigs of N50 = 14 Mb, scaffolds of N50 = 65 Mb, and BUSCOs value of 98.5%. The newly assembled genome has better continuity and integrity than the previously reported white clover reference genome; thus provides important resources for the molecular breeding and evolution of white clover and other forage. Additionally, we annotated 90,128 high-confidence gene models from the genome. White clover was most closely related to Trifolium pratense and Trifolium medium but distantly related to Glycine max, Vigna radiata, Medicago truncatula, and Cicer arietinum. The expansion, contraction, and GO functional enrichment analysis of the gene families showed that T. repens gene families were associated with biological processes, molecular function, cellular components, and environmental resistance, which explained its excellent agronomic traits.
Conclusions: This study reports a high-quality de novo assembly for white clover obtained at the chromosomal level using PacBio third-generation Hi-Fi sequencing. The generated high-quality genome assembly of white clover provides a key basis for accelerating the research and molecular breeding of this important forage crop. The genome is also valuable for future studies on legume forage biology, evolution, and genome-wide mapping of quantitative trait loci associated with the relevant agronomic traits.
Investigation on Hydrogen Storage Capacity of Spherical Activated Carbons from Ion Exchange Resins
Authors: Kim Tae Gyun , Hong Yeon Soo , Lee Chang Ha , Suh Jeong Kwon 
Published: March 2023

Abstract
In this study, the role of spherical activated carbon from ion exchange resin as an adsorption material for hydrogen storage was researched. Spherical activated carbon samples were prepared from two types of physical activation methods using steam and CO2. The porosity induced by each method and the resulting hydrogen adsorption performance were compared and evaluated. When the samples had similar BET surface areas, steam activation induced microporous spherical activated carbon to increase hydrogen storage performance at low pressure (~1 bar) under low temperature conditions (under 77 K). CO2 activation was able to well formation of the 1-2 nm sized pore ratio in the micropores, thus enhancing hydrogen storage performance at high pressure (~200 bar) under ambient temperature (under 298 K). In conclusion, this indicated that there exists a range of spherical activated carbon pore size favorable for hydrogen adsorption, dependent on the pressure range applied.
Can we determine anterior hip coverage from pelvic anteroposterior radiographs? A study of patients with hip dysplasia
Authors: Cheng Hui , Zhang Zhendong , Sun Wei , Ren Ningtao , Luo Dianzhong , Li Yong , Zhang Jianli , Zhang Hong 
Published: March 2023

Abstract
Purpose: Insufficient coverage causes hip joint instability and results in hip pain. Anterior hip coverage can be determined on both pelvic anteroposterior (AP) radiographs and false profile (FP) radiographs. Four parameters are commonly used to determine the anterior coverage on pelvic AP radiographs: the crossover index, crossover sign, anterior wall index (AWI), and rule of thirds. This study aims to clarify the relationship between these 4 parameters on AP radiographs and the anterior center edge angle (ACEA) on FP radiographs.
Methods: In this study, 53 patients who underwent periacetabular osteotomy for hip dysplasia at our center between July 2020 and October 2020 were retrospectively reviewed. Four parameters on AP radiographs and the ACEA on FP radiographs before surgery and 6 months after surgery were measured and compared for each hip.
Results: Upon examining the 53 hips in this study, there was no correlation between either the crossover index and the ACEA (P=0.66) or the crossover sign before surgery. The postoperative correlation between the crossover index and the ACEA was weak (r=0.36, P=0.007), and that between the crossover sign and the ACEA was moderate (r=0.41, P=0.003). There was a weak correlation between the AWI and ACEA both before (r=0.288, P=0.036) and after (r=0.349, P=0.011) the operation. Evaluation of the anterior coverage by the rule of thirds was also not consistent when determining the anterior coverage with the ACEA.
Conclusion: Anterior coverage on AP radiographs is largely inconsistent with ACEA on FP radiographs, especially before the surgery. It is recommended to take FP radiographs routinely for determining anterior hip coverage.
Chronic low-concentration benzene exposure and hematotoxicity research trends from 1992 to 2022
Authors: 胡 娟 , Sun Qianyu , Xu Fanwei , Zhang Ludi , LI Xiuting , Zhu Baoli , Wang Boshen 
Published: March 2023

Abstract

Background
The purpose of this study was to analyze nearly three decades of academic research on chronic low-level benzene exposure and hematotoxicity with qualitative and quantitative analysis.
Methods
Publications from 1992 to 2022 were extracted from the Science Citation Index Expanded (SCI-E) and the Social Sciences Citation Index (SSCI) of the Web of Science Core Collection (WoSCC) of Thomson Reuters. WoSCC, Microsoft Excel 2016, and Citespace were used to analyze the publication outcomes, journals, countries, institutions, authors, and research areas.
Results
As of July 13, 2022, there have been 521 papers published on chronic low-level benzene exposure and hematotoxicity. Environmental Health Perspectives has published the most articles, the United States is the leading country, Fudan University is the leading institution, Chen Y has published the most articles, Snyder R has co-cited the most articles, and Toxicology is ranked #1 in the research field.
Conclusion
Many high-quality articles have been published in the last three decades. Fudan University and the Chinese Center for Disease Control and Prevention are in the first echelon of research on long-term low-level benzene exposure and hematological toxicity. Chen Y, Ashley D, and Bertazzi P may be good candidates for collaboration in this research area. In the meantime, occupational disease researchers should pay close attention to the studies of hematological and carcinogenicity caused by occupational benzene exposure.
Evaluate the Efficacy of Endodontic Microsurgery on Teeth Having Undeveloped Root Apex Failed in Non-surgical Treatment with Periapical Inflammation
Authors: Tang Yumu , Xu Ke , Chen Yumao , Lu Le 
Published: March 2023

Abstract
Background: To evaluate the efficacy of endodontic microsurgery on teeth with undeveloped root apex and periapical inflammation caused by an abnormal central cusp fracture due to failed nonsurgical treatment.
Methodology: We performed endodontic microsurgery on 80 teeth in 78 patients with undeveloped root apex and periapical inflammation caused by an abnormal central cusp fracture due to failed nonsurgical treatment. All patients were clinically and radiologically examined 1 year after surgery, and the data were statistically analyzed using the SPSS 27.0 software package.
Results: Of 80 teeth in 78 patients, periapical lesions disappeared in 77 teeth at the 1-year postoperative follow-up, with a success rate of approximately 96.3% (77/80). Sex, age, extent of periapical lesions, and the presence of the sinus tractdid not affect the efficacy of endodontic microsurgery. The differences between groups were not statistically significant (P > 0.05).
Conclusions: On failure of nonsurgical treatment in teeth with undeveloped root apexand periapical inflammation caused by an abnormal central cusp fracture, endodontic microsurgery may be a good clinical treatment option.
The impact of the COVID-19 pandemic on the residential aged care sector, responses and recommendations: A systematic scoping review
Authors: Battams Samantha , Martini Angelita 
Published: March 2023

Abstract

Objective:This systematic scoping review sought to identify the impact of the COVID-19 pandemic on the residential aged care (RAC) sector, its system components, and the range of COVID-19 response strategies across the sector.Methods: ProQuest, PubMed, CINAHL, Google Scholar and Cochrane Central were searched April-August 2022 for peer reviewed articles and grey literature. One hundred and forty six articles on the impact of the COVID-19 pandemic on the RAC sector and sector interventions/policy responses are included in this review.Results:The World Health Organization’s (WHO) six building blocks of health systems were used to categorise impacts and interventions. The COVID-19 pandemic generally highlighted poor resourcing of the RAC sector and exacerbated workforce shortages; led to increased workload, changes in job demand and declines in worker mental health; revealed poor integration across health and aged care sectors and reduced advance care and palliative care planning. Social restriction measures led to declines in the physical, mental health and cognitive decline of residents in RACFs, in particular those with cognitive impairment. Innovative care models included the introduction of outreach teams and primary care models for RACFs and increased use of telehealth and videoconferencing for social engagement, although there was mixed evidence on the use of telehealth for people with cognitive impairment.Discussion:Additional funding of the RAC sector is required to boost workforce numbers and training, and support worker mental health, along with policies which attract, maintain and support workers from culturally and linguistically diverse (CALD) backgrounds. COVID-19 response strategies in RACFs need to ensure that all residents have access to resources such as telehealth for health and social engagement, including residents with cognitive impairment. Clear guidelines and additional resourcing are required for utilisation of telehealth during a pandemic. Additional research on appropriate COVID-19 responses for residents with cognitive impairment is required, along with a balance between infection prevention and control and social engagement strategies.
Supportive care and information needs of men following prostate cancer treatment: a qualitative study
Authors: Blackmore Tania , Chepulis Lynne , Burrett Vanessa , Akapita Teresa , Kidd Jacquie , Devcich Glen , Holmes Michael , Lawrenson Ross 
Published: March 2023

Abstract
Purpose

To assess the psychosocial and informational needs of prostate cancer survivors who had attended an information session designed to help men better understand their diagnosis and treatment options.

Methods

We thematically analysed the qualitative interviews of 12 prostate cancer survivors and identified emerging themes related to psychosocial and informational needs following treatment.

Results

The most common source of psychosocial distress was side effects related to androgen deprivation therapy. Young men exhibited higher levels of distress than older men. All men were reluctant to seek psychosocial support, and despite attending the information session, still expressed a desire for more information and clarity around their diagnosis and treatment options.

Conclusions

A minority of prostate cancer survivors experience ongoing psychosocial needs associated with treatment side effects. These men often expressed treatment regret, but did not seek support for their distress, highlighting a barrier that prevents male help-seeking.

Implications for Cancer Survivors

The provision of an additional information session offers a vital service to patients and has the potential to help bridge the difficult period between initial diagnosis and treatment, when prostate cancer patients must make important health decisions. Further investment in information sessions is needed to meet the informational needs of prostate cancer patients.
An in-depth analysis of perinatal related mortality among women of South Asian ethnicity in Aotearoa New Zealand, compared to other ethnic groups
Authors: de Graaff Esti , Sadler Lynn , Lakhdhir Heena , Simon-Kumar Rachel , Peiris-John Roshini , Burgess Wendy , Okesene-Gafa Karaponi , Cronin Robin , McCowan Lesley , Anderson Ngaire 
Published: March 2023

Abstract
Background: International and national New Zealand (NZ) research has identified women of South Asian ethnicity at increased risk of perinatal mortality, in particular stillbirth, with calls for increased perinatal research among this ethnic group. We aimed to analyse differences in pregnancy outcomes and associated risk factors between South Asian, Māori, Pacific, and New Zealand European women in Aotearoa NZ, with a focus on women of South Asian ethnicity, to ultimately understand the distinctive pathways leading to adverse events.
Methods: Clinical data from perinatal deaths between 2008 and 2017 were provided by the NZ Perinatal and Maternal Mortality Review Committee (PMMRC), while national maternity and neonatal data, and singleton birth records from the same decade were linked using the Statistics NZ Integrated Data Infrastructure for all births. Pregnancy outcomes and risk factors for stillbirth and neonatal death were compared between ethnicities with adjustment for pre-specified risk factors.
Results: Women of South Asian ethnicity were at increased risk of stillbirth (aOR 1.51, 95%CI 1.29-1.77), and neonatal death (aOR 1.51, 95%CI 1.17-1.92), compared to NZ European. The highest perinatal related mortality rates among South Asian women were between 20-22 weeks gestation (at 1.3 and 1.1/1,000 ongoing pregnancies; p<0.01 compared to NZ European) and at term, although differences by ethnicity at term were not apparent until ≥41 weeks (p<0.01 compared to NZ European). No major differences in known and collected risk factors for stillbirth and neonatal death were observed between ethnicities. Among perinatal deaths, South Asian women were overrepresented in a range of metabolic-related disorders, such as gestational diabetes, pre-existing thyroid disease, or maternal red blood cell disorders (all p<0.05 compared to NZ European).
Conclusions: Women of South Asian ethnicity in Aotearoa NZ were at increased risk of stillbirth and neonatal death compared to NZ European women. Metabolic-related factors may contribute to adverse pregnancy outcomes in South Asian mothers.
Considering Costs in Health Professions Education: A Scoping Review Protocol
Authors: Yaros J.K. , Mortier C.A. , Egbrink M.G.A. oude , Evers S.M.A.A. , Paulus A.T.G. 
Published: March 2023

Abstract
Background
Profound changes in the healthcare sector and the global shortage of healthcare workers are driving the demand to update and scale-up health professions education (HPE). At the same time, educational institutions are contending with resource scarcity and the decision of where and how to allocate resources must be made conscious of cost. To improve rigor in the economic evidence generated for such decisions, it is necessary to have a better understanding of which costs and costing methods are relevant to HPE. Therefore, this protocol has been developed to outline the rationale and methods for a scoping review of the literature intended to map the current state of cost evidence for HPE.
Methods
This protocol is developed in accordance with the Joanna Briggs Institute Manual for Evidence Synthesis and PRISMA-ScR guidelines. PubMed, ERIC, CINAHL and PsycInfo will be scoped for all types of English language publications from 2012 onward that investigate costs associated with the education of health professionals. Two independent reviewers will assess publications for eligibility. Data will be extracted on the topic of investigation, educational setting, level of education, type of economic evaluation, methods for cost identification, stakeholder perspective and individual cost components.
Discussion
This protocol presents the initial concept for an exploratory review of the costs associated with HPE. This format was chosen for its iterative nature, which allows this relatively unexplored topic to be broadly scoped from multiple educational and economic databases and simultaneously narrowed in focus in response to the discovery of evidence. The results from this planned investigation will provide an overview of the existing evidence on costs and costing methods in HPE, which can be used to set a research agenda on economics of HPE and contribute to cost conscious HPE in practice.
Trial Registration
This protocol was prospectively registered on Open Science Framework (OSF) on June 13, 2022 and is available at https://doi.org/10.17605/OSF.IO/ET4XB.
The neuromorphic Mosaic: in-memory computing and routing for small-world graphical networks
Authors: Dalgaty Thomas , Moro Filippo , Demirağ Yiğit , De Pra Alessio , Indiveri Giacomo , Vianello Elisa , Payvand Melika 
Published: March 2023

Abstract
The connectivity in the brain is locally dense and globally sparse - giving rise to a small-world graph. This is a principle that has persisted during the evolution of many species - indicating a universal solution to the efficient routing of information. However, existing circuit architectures for artificial neural networks neither leverage this organization nor do they efficiently support small-world neural network models. Here, we propose the neuromorphic Mosaic: a non-von Neumann systolic architecture that uses distributed memristors, not only for in-memory computing, but also for in-memory routing, to efficiently implement small-world graph topologies. We design, fabricate, and experimentally demonstrate the building blocks of this architecture, using integrated memristors with 130 nm CMOS technology. We demonstrate that neural networks implemented following this approach can achieve competitive accuracy figures compared to equivalent unconstrained and full-precision networks, for three real-time benchmarks: classification of electrocardiography signals, keyword spotting and motor control via reinforcement learning. The Mosaic shows improvements between one and four orders of magnitude, compared to other event-based neuromorphic architectures for routing events across the network. The Mosaic opens up a new scalable approach for designing edge AI systems based on distributed computing and in-memory routing, offering a natural platform onto which architectures inspired by biological nervous systems can be readily mapped.
Enhancement in ionic conductivity of liquid crystals by graphene/metal-oxide-nanocomposite
Authors: Khodaee M. , Dalir N. , Feghhi F. , Ansari N. , Mohammadimasoudi M. , Goudarzi A. , Nasiri A. Faghih , Kolahdouz M. , Mohseni S. M. 
Published: March 2023

AbstractEnhancing the ionic conductivity of liquid crystal (LC) circumvents challenges for application in advanced electronic components. Toward this, using additives made of different nanostructures that could result in functional LCs is suggested. In this paper, various concentrations of graphene (Gr)/metal-oxide (Fe3O4) nanocomposite (GMN) (0.0001-1 w%) were added to E7 nematic LC. We found that the role of anisotropic Gr flakes, their edges as well as surface-decorated-metal-oxide-additives have significant impact on electrical properties of E7. A range of appropriate additives of such a nanocomposite enhances the electrical conductivity of LCs. This effect can be traced through the decrease in the formation of GMN aggregates in the E7 and increase in the electrostatic field at the edges of the Gr sheets. Moreover, the presence of metal-oxide nanoclusters due to the presence of oxygen vacancies and defects facilitates the construction of conductive network for improving the charge transfer pathways and contributes to a stronger interaction of the Gr surface with charged species. These factors can provide Gr layers as dipole moments and lead to signal propagation in the dielectric medium. Our finding conveys a pathway toward significant enhancement of ionic conductivity in the LC family which can be useful for functional applications.
Individual differences in knowledge network navigation
Authors: Zhu Manran , Yasseri Taha , Kertész János 
Published: March 2023

Abstract
As online information accumulates at an unprecedented rate, it is becoming increasingly important and difficult to navigate the web efficiently. To create an easily navigable cyberspace for individuals across different age groups, genders, and other characteristics, we first need to understand how they navigate the web differently. Previous studies have revealed individual differences in spatial navigation, yet very little is known about their differences in knowledge space navigation. To close this gap, we conducted an online experiment where participants played a navigation game on Wikipedia and filled in questionnaires about their personal information. Our analysis shows that participants' navigation performance in the knowledge space declines with age and increases with foreign language skills. The difference between male and female performance is, however, not significant in our experiment. Participants' characteristics that predict success in finding routes to the target do not necessarily indicate their ability to find innovative routes.
Comparative study of antennal sensilla in irradiated male and female fall armyworm, Spodoptera frugiperda with gamma radiation
Authors: Zahran Nagwan , Hamza Ali , Kandil Mervat 
Published: March 2023

Abstract
Morphology of the Fall Armyworm (FAW) Spodoptera frugiperda adult antenna was photographed by Scanning Electron Microscope (SEM). The type of the antenna is filiform, and consists of three main segments: the scape, pedicel and flagellum. Scanning of antennae revealed the presence of eight types of sensilla in male and seven in female which are Sensillum Squamiformia, Scales, Sensillum Styloconica, Sensillum Trichodea, Sensillum Chaetica lateral and central, Sensillum Coeloconica, Sensillum Auricillica and Sensillum Basiconica which are distributed among the antennal segments. These types of sensilla found in both sexes except Sensillum Styloconica. The effect of four doses of gamma radiation (50, 100, 150 and 200 Gy) on the antennal sensilla were studied. These studies revealed that these higher doses in both sexes have certain malformation features in the sensilla. The magnitude of these malformations was dose dependent as they increased by increment of the doses applied. These malformations in the sensilla and its role in courtship and mating inhibition were discussed.