bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of MCS program on brain-derived neurotrophic factor, interleukin-6, 25-hydroxy vitamin D and depression among office workers with mild depression
Authors:   , Taworntawat Chirra 
Published: April 2023

Background: Globally, major depressive is the primary cause of disability. A large part of cases is reported among the working-class. Literature reviews suggest that the disorder is tied in with immune dysregulation and inflammatory response. This study aimed to assessed MCS (mindfulness meditation + curcumin supplementation + sunlight exposure) program by comparing with a control group among mildly depressed office workers.

Methods: A quasi experiment was conducted with a total of 68 male and female office workers, n=34 being treatment group (TG) and n=34 being control group (CG). The groups were compared in terms of (a) serum brain-derived neurotrophic factor (BDNF), (b) serum interleukin-6 (IL-6), (c) serum 25-hydroxyvitamin D (vitamin D), and (d) depression scores of PHQ-9. Multiple Linear Regression and Fixed Effect Model were used to test effects of the intervention.

Results: BDNF values differ significantly at base line but saw a sudden rise in [day 0, day 30] interval and a decline in [day 30, day 60] interval in CG. IL-6 outcomes at baseline showed no significant differences between groups, and the combined groups saw a modest but significant increase in [day 0, day 30] interval and a decrease in [day 30, day 60] interval. Notably, IL-6 was significantly lower in TG at day 30 than CG (P<0.05). For vitamin D, the rates of increase in both [day 0, day 30] and [day 30, day 60] intervals were significantly higher in TG than CG (P<0.05). In addition, there were significant differences between the groups at day 30 and day 60 with no notable confounding factors for vitamin D. Depression scores of TG demonstrated an appreciable decline in [day 0, day 30] interval and stayed down until the end of the study whereas of CG saw no changes throughout the study. Moreover, lower depression scores were observed for TG at both day 30 and day 60 (P<0.05).

Discussion: MCS program resulted in significant decreases in depression scores, a rise in vitamin D, and a drop in IL-6, thus can be a successful and inexpensive approach to alleviating depressive symptoms for depression among the working-class.
Penerapan Pendekatan Group Problem Solving Untuk Meningkatkan Hasil Belajar Matematika Siswa Kelas VII B Semester 1 SMP Negeri 1 Semarapura Tahun Pelajaran 2022/2023
Authors: Taman Ni Komang 
Published: April 2023

Penelitian ini bertujuan untuk meningkatkan hasil belajar matematika siswa kelas VII B SMP Negeri 1 Semarapura tahun pelajaran 2022/2023 dengan penerapan pendekatan group problem solving. Jenis penelitian ini adalah penelitian tindakan kelas yang dilaksanakan dalam dua siklus. Setiap siklus terdiri dari tahap perencanaan, pelaksanaan tindakan, observasi/evaluasi, dan refleksi. Subjek penelitian ini adalah siswa kelas VII B SMP Negeri 1 Semarapura tahun ajaran 2022/2023 sebanyak 39 orang. Data tentang hasil belajar matematika siswa dikumpulkan melalui tes berbentuk pilihan ganda. data yang dikumpulkan dianalisis menggunakan analisis deskriptif. Hasil penelitian menunjukkan bahwa penerapan pendekatan group problem solving, dapat meningkatkan hasil belajar matematika siswa kelas VII B SMP Negeri 1 Semarapura, yaitu dari nilai rata-rata sebesar 78,38 dengan daya serap 78,38% dan ketuntasan klasikal 76,92% pada siklus I dan rata-rata nilai menjadi 84,59, dengan daya serap 84,59 dan ketuntasan klasikal 92,31% pada siklus II dan berada pada kualifikasi baik. Selain itu, respon belajar siswa terhadap pembelajaran matematika yang diterapkan tergolong tinggi.
Popullsia e kazave Dibër e Epërme dhe Dibër e Poshtme në regjistrat osmanë (1845 - 1858)
Authors: Gjoni Alketa , Saygili Doç. Dr. Hasip 
Published: April 2023

Pas prezantimit të një historie të shkurtër të këtyre regjistrimeve të bëra gjatë shekujve, ky punim shqyrton demografinë e zonës së Dibrës nga Periudha e reformës së Tanzimatit (1839) deri në vitin 1858, periudhë në të cilën Dibra ishte një pjesë administrative e sanxhakut të Ohrit të Vilajetit të Rumelisë dhe ndahej në Kazanë e Dibrës së Sipërme dhe në Kazanë e Dibrës së Poshtme.
Gjithashtu në bazë të këtyre regjistrave është analizuar struktura demografike dhe faktorët ndikues në këtë strukture, ku nëpërmjet të dhënave të këtyre regjistrave bëhet e mundur pasqyra nga numri i përgjithshëm i shtëpive, numri i popullsisë dhe klasifikimi i kësaj popullate në kategori sipas moshës ose pasurisë.
Gjatë analizës, këto të dhëna i kemi llogaritur në përqindje, duke mundësuar krahasimin e demografisë së viteve të marra në studim.
Sa i përket zonës së marrë në studim, mund të thuhet që nuk ka ndodhur regjistrimi i vitit 1831. Regjitrime të popullsisë së kësaj zone në funksion të realizimit të reformave të Tanzimatit, i përkasin periudhës kohore midis viteve 1845-1858, ku Dibra kishte statusin e kazasë dhe administrativisht bënte pjesë në Sanxhakun e Ohrit të Vilajetit të Rumelisë. Në këto deftere Dibra ishte e ndarë në Kazanë e Dibrës së Sipërme dhe në Kazanë e Dibrës së Poshtme.
Mbi disa lloje të ligjërimit në Kuran
Authors: Suma Dr. Rexhep 
Published: April 2023

Libri i shenjtë, Kurani Famëlartë, është fjalë e Allahut (xh.sh.) që e ka zbritur në periudhën kohore prej 23 vitesh mbi të Dërguarin e fundit, Muhamedin (a.s.). Si i tillë, ai ka sfiduar botërat dhe çdo krijesë. Kurani përçon në vetvete jetë, ilustrim dhe frymëzim shpirtëror dhe qenia njerëzore e ka të pamundur të japë shpjegimin mbi sekretin e këtij fenomeni. Fjalët e tij dëshmojnë mjaft mirë, se është e pamundur të imitohet Kurani dhe stili i rrëfimeve të tij është i paarritshëm.
Kurani i dhuron myslimanit vizion të plotë dhe program të qartë, të ngjeshur dhe jetën ia bën të ecë në vijën e ekuilibruar, duke mos u ndeshur me asgjë tërë kohën. Ky vizion, po ashtu, e unifikon diturinë me besimin, duke bërë që njeriu, pas materies, të jetë përsëri me materien. Po ashtu, ky vizion lidh sekretet me emocionet e ndjeshme dhe asnjëherë nuk i lë ato që të ndahen. Është tashmë e ditur që, nëse ne do t’i përmbahemi vizionit kuranor dhe do të meditonim për shenjat e Zotit te krijesat, do të kishim një psikologji e cila do të njihte madhështinë e Krijuesit, që kur e ka krijuar njeriun.
SISTEM INFORMASI AKUNTANSI PENERIMAAN DAN PENGELUARAN KAS BERBASIS WEB PADA STMIK PRIMAKARA
Authors: Purnama Ni Komang Arix , A.A Istri Ita Paramitha  , Ni Made Estiyanti  
Published: April 2023

STMIK Primakara is aInformatics and Computer College which of course cannot be separated from the existence of computerization. Most of the systems that are there are already computerized, including the processing of financial data. Where financial data processing, there is a process of cash receipts and payments like companies in general. This study discusses the development of an information system for cash receipts and disbursements at STMIK Primakara. This researchwas conducted using the Linear Sequential method. This research uses the PHP programming language with a code igniter framework. This research succeeded in developing a cash management information system, especially cash receipts and disbursements at STMIK Primakara. From the results of interviews with users conducted by researchers, responses from those who will use this system are quite positive because it canfacilitate them in the process of managing financial data.
An integrated leaf trait analysis of two Paleogene leaf floras
Authors: Müller Christian , Toumoulin Agathe , Böttcher Helen , Roth-Nebelsick Anita , Wappler Torsten , Kunzmann Lutz 
Published: April 2023

ObjectivesThis study presents the Integrated Leaf Trait Analysis (ILTA), a workflow for the combined application of methodologies in leaf trait and insect herbivory analyses on fossil dicot leaf assemblages. The objectives were (1) to record the leaf morphological variability, (2) to describe the herbivory pattern on fossil leaves, (3) to explore relations between leaf morphological trait combination types (TCTs), quantitative leaf traits, and other plant characteristics (e.g., phenology), and (4) to explore relations of leaf traits and insect herbivory.Material and MethodsThe leaves of the early Oligocene floras Seifhennersdorf (Saxony, Germany) and Suletice-Berand (Ústí nad Labem Region, Czech Republic) were analyzed. The TCT approach was used to record the leaf morphological patterns. Metrics based on damage types on leaves were used to describe the kind and extent of insect herbivory. The leaf assemblages were characterized quantitatively (e.g., leaf area and leaf mass per area (LMA)) based on subsamples of 400 leaves per site. Multivariate analyses were performed to explore trait variations.ResultsIn Seifhennersdorf, toothed leaves of TCT F from deciduous fossil-species are most frequent. The flora of Suletice-Berand is dominated by evergreen fossil-species, which is reflected by the occurrence of toothed and untoothed leaves with closed secondary venation types (TCTs A or E). Significant differences are observed for mean leaf area and LMA, with larger leaves tending to lower LMAin Seifhennersdorf and smaller leaves tending to higher LMAin Suletice-Berand. The frequency and richness of damage types are significantly higher in Suletice-Berand than in Seifhennersdorf. In Seifhennersdorf, the evidence of damage types is highest on deciduous fossil-species, whereas it is highest on evergreen fossil-species in Suletice-Berand. Overall, insect herbivory tends to be more frequently to occur on toothed leaves (TCTs E, F, and P) that are of low LMA. The frequency, richness, and occurrence of damage types vary among fossil-species with similar phenology and TCT. In general, they are highest on leaves of abundant fossil-species.DiscussionTCTs reflect the diversity and abundance of leaf architectural types of fossil floras. Differences in TCT proportions and quantitative leaf traits may be consistent with local variations in the proportion of broad-leaved deciduous and evergreen elements in the ecotonal vegetation of the early Oligocene. A correlation between leaf size, LMA,and fossil-species indicates that trait variations are partly dependent on the taxonomic composition. Leaf morphology or TCTs itself cannot explain the difference in insect herbivory on leaves. It is a more complex relationship where leaf morphology, LMA, phenology, and taxonomic affiliation are crucial.
The Wound Healing Potential of 2,3 Dimethylquinoxaline Hydrogel in Rat Excisional Wound Model
Authors: Elfadil Abdelbagi , Ali Ahmed S. , Alrabia Mohammad W. , Alsamhan Hamoud , Abdulmajed Hind , Abu Ibrahim Ismail Mohammed , Allibaih Mohammad , Ahmed Khalid Hussein Bakheit 
Published: April 2023

Background: 2,3-dimethylquinoxaline (DMQ) is a naturally occurring compound with documented antifungal activity. It showed also good in vitro physicochemical and pharmacokinetic characteristics.
Methods: The wound healing activity of 1% DMQ hydrogel in healthy adult male Wister rats were evaluated using the excision wound model. On day 7, the mean percentage closure of the wound area was determined. The animals were sacrificed on day 7 and skin was isolated for histology research and assessment of some inflammatory & oxidative markers, hydroxyproline and tissue growth factor.
Results and Discussion: Almost complete wound healing was observed after treatment with DMQ 1 % Jell for 7 days. The histological study confirmed marked attenuation of wound-induced histological changes. There was a marked reduction in TNF-α, IL-6 IL-β1 and NF-κB. levels. These data suggest the potential anti-inflammatory effect of DMQ.
Conclusion: DMQ has potential skin wound healing ability likely due to its anti-inflammatory mechanism. Further study is needed to confirm these preliminary findings and explore the molecular mechanism
Association Between Early Prostacyclin Therapy and Extracorporeal Life Support Use in Patients With Congenital Diaphragmatic Hernia
Authors: Ramaraj Akila B. , Rice-Townsend Samuel E. , Foster Carrie L. , Yung Delphine , Jackson Emma O. , Ebanks Ashley H. , Harting Matthew T. , Stark Rebecca A. ,   Congenital Diaphragmatic Hernia Study Group, Lally Kevin , Lally Pam , Boyd Yvette 
Published: April 2023

ImportanceProstacyclin (PGI2) is a therapeutic option to treat congenital diaphragmatic hernia (CDH)–associated pulmonary hypertension in neonates. Its use may decrease the need for extracorporeal life support (ECLS).ObjectiveTo evaluate the association of early PGI2 therapy with ECLS use and outcomes among patients with CDH.Design, Setting, and ParticipantsThis was a cohort study from the CDH Study Group (CDHSG) registry of patients born from January 2007 to December 2019. Patients were from 88 different tertiary pediatric referral centers worldwide that contributed data to the CDHSG. Patients were included in the study if they were admitted within the first week of life. Propensity score matching was performed using estimated gestational age, birth weight, transfer status, 1-minute and 5-minute Apgar scores, highest and lowest partial pressure of arterial carbon dioxide in the first 24 hours of life, and degree of pulmonary hypertension as covariates to generate a matched cohort of exposed and unexposed patients. Data were analyzed from January 2021 to December 2022.ExposuresEarly PGI2 therapy was defined as initiation of PGI2 within the first week of life. Patients who received ECLS were included in the early PGI2 group if PGI2 was started prior to ECLS.Main Outcomes and MeasuresThe primary outcome of the study was the proportion of patients receiving ECLS in the exposed and unexposed groups.ResultsOf 6227 patients who met inclusion criteria (mean [SD] gestational age, 37.4 [2.36] weeks; 2618 [42%] female), 206 (3.3%) received early PGI2 therapy. ECLS was used in 46 of 206 patients who received PGI2 (22.2%) and 1682 of 6021 who did not (27.9%). After propensity score matching, there were 147 patients in the treatment and control groups. Thirty-four patients who received PGI2 (23.3%) and 63 who did not (42.9%) received ECLS. Those who received PGI2 were less likely to receive ECLS (adjusted odds ratio, 0.39; 95% CI, 0.22-0.68) and had shorter mean (SD) duration of ECLS (8.6 [3.73] days vs 12.6 [6.61] days; P &amp;lt; .001), although there was no significant difference in in-hospital mortality.Conclusions and RelevanceIn this study, there was decreased use of ECLS and decreased ECLS duration among patients with CDH who started PGI2 therapy during the first week of life. These results identify a potential advantage of early prostacyclin therapy in this population.
Deconstructing insect herbivore trivial movement in a monoculture and triculture: Limitations of emigration
Authors: Andow David A. 
Published: April 2023

AbstractSignificantly higher population densities of a squash pest beetle, Acalymma vittatum, were observed in a squash monoculture than a triculture of squash, maize, and beans. One hypothesis for such differences is that non‐host plants in the triculture cause the herbivore to move more frequently resulting in higher emigration rates from the tricultures. Plant to plant movement of the beetle was studied in vegetative winter squash to evaluate if differences in components of trivial movement would generate a higher emigration rate from the triculture. Tenure times were shorter on plants in the triculture than on plants in the squash monoculture, there was no movement directionality, movement distances were greater in squash monocultures than in tricultures and were greater during July than August. In the tricultures, plant‐to‐plant transitions were primarily to maize from non‐host plants and to beans or squash from host plants during July, but during August, movement from any plant was primarily to maize. We integrated the values of the movement components from vegetative winter squash into a simple Markov model, and found that during July, emigration was estimated to be faster from the triculture than the monoculture, supporting the hypothesis. However, in August, emigration was estimated to be slower from the triculture. In August, maize plants were tall and, by acting like a fence, greatly reduced the movement distance of beetles. The effect of the differences in emigration rate on beetle population density was greatest for small patches, indicating that emigration may be important only in small‐scale production systems.
Small Molecules, Great Powers: Chemistry of Small Organo‐Chalcogenide Molecules in Rechargeable Li‐Sulfur Batteries
Authors: Zhou Jinqiu , Qian Siyi , Hao Baojiu , Liu Jie , Zhou Xi , Yan Chenglin , Qian Tao 
Published: April 2023

AbstractSmall organic chalcogenides molecules are receiving more attention in conjunction with the development of rechargeable lithium metal batteries (LMBs) especially lithium–sulfur (Li−S) batteries due to their abundant resources, reversible redox, high capacities, tunable structures, unique functional adjustability, and strong interaction with congener polysulfides. In this review, the working principles are generalized of small organo‐chalcogenide molecules in three important parts of batteries: electrolyte, interface, and cathode. First, in terms of regulating kinetics in electrolyte, small organo‐chalcogenide molecules can not only act as redox mediator to accelerate the redox kinetics of sulfur, but also change the inherently slow solid–solid process to form a faster redox pathway, which will bring light to the development of cryogenic Li−S batteries. Second, for interface chemistry, the introduction of small organo‐chalcogenide molecules can construct more elastic and stable anodic single‐SEI or cathodic/anodic dual‐SEI, thus effectively improving the cycling stability of batteries. Third, small organo‐chalcogenide molecules can be used as cathode materials in the form of liquid phase, solid phase, or precursor of polymers. Finally, advised optimizations are proposed about further mechanism deciphering, battery configuration design, machine learning, thereby providing direction to bridge the gap between rational modulation and practical battery implementation for small organo‐chalcogenide molecules.
In Situ Construction of High‐Density Solid Electrolyte Interphase from MOFs for Advanced Zn Metal Anodes
Authors: Xiong Dengyi , Yang Li , Cao Ziwei , Li Fengrong , Deng Wentao , Hu Jiugang , Hou Hongshuai , Zou Guoqiang , Ji Xiaobo 
Published: April 2023

AbstractAqueous zinc anode has been re‐evaluated due to the superiority in tackling safety and cost concerns. However, the limited lifespan originating from Zn dendritic and side reactions largely hamper commercial development. Currently, the coating prepared by simple slurry mixing is leaky and ineffectively isolate sulfate and water. Herein, inspired by the DFT calculations and the easy hydrolysis characteristic of MIL‐125 (Ti), an in‐situ grown high‐dense TiO2‐x solid electrolyte interphase (HDSEI) with rich oxygen vacancies is successfully constructed in an aqueous electrolyte, in which the oxygen vacancies not only strengthen the hydrogen binding force thereby inhibiting the hydrogen precipitation by‐reaction, but also reduce the migration energy barrier of zinc ions and enhance the mechanical properties. Profiting from the HDSEI, symmetric Zn cells survive up to remarkable 4200 h at 1 mA cm−2, nearly 42‐times than that of bare Zn anodes. In situ optical microscopy clearly reveals that the in situ grown HDSEI homogenizes the zinc deposition process, while bare zinc without HDSEI shows significant dendrites, confirming the protective nature of HDSEI. Furthermore, full Zn ion capacitors can deliver excellent electrochemical performance, providing a feasible in situ approach to construct HDSEI to implement dendrite‐free metal anodes.
A Sulfur Heterocyclic Quinone Cathode Towards High‐Rate and Long‐Cycle Aqueous Zn‐Organic Batteries
Authors: Sun Qi‐Qi , Sun Tao , Du Jia‐Yi , Li Kai , Xie Hai‐Ming , Huang Gang , Zhang Xin‐Bo 
Published: April 2023

AbstractOrganic materials have attracted much attention in aqueous zinc‐ion batteries (AZIBs) due to their sustainability and structure‐designable, but their further development is hindered by the high solubility, poor conductivity, and low utilization of active groups, resulting in poor cycling stability, terrible rate capability, and low capacity. In order to solve these three major obstacles, a novel organic host, benzo[b]naphtho[2’,3’:5,6][1,4]dithiino[2,3‐i]thianthrene‐5,7,9,14,16,18‐hexone (BNDTH), with abundant electroactive groups and stable extended π‐conjugated structure is synthesized and composited with reduced graphene oxide (RGO) through a solvent exchange composition method to act as the cathode material for AZIBs. The well‐designed BNDTH/RGO composite exhibits a high capacity of 296 mAh g−1 (nearly a full utilization of the active groups), superior rate capability of 120 mAh g−1, and a long lifetime of 58 000 cycles with a capacity retention of 65% at 10 A g−1. Such excellent performance can be attributed to the ingenious structural design of the active molecule, as well as the unique solvent exchange composition strategy that enables effective dispersion of excess charge on the active molecule during discharge/charge process. This work provides important insights for the rational design of organic cathode materials and has significant guidance for realizing ideal high performance in AZIBs.
MXene‐Based Flexible Sensors: Materials, Preparation, and Applications
Authors: Du Tao , Han Xin , Yan Xiuling , Shang Jiangwei , Li Yao , Song Jianbin 
Published: April 2023

AbstractThe rational design and applications of MXene‐based materials have yielded remarkable progress in flexible sensors, including wearable devices, soft robots, and smart medical equipment. The emerging MXene and substrate materials can be precisely engineered to improve the mechanical properties and sensing sensitivity of the sensors, opening up a wider range of application possibilities for MXene‐based sensors. Therefore, a systematic and comprehensive review summarizing the progress of MXene‐based sensor research based on these backgrounds is necessary. First, we discuss the basic structure of MXene materials and introduce the flexible substrate materials for MXene‐based flexible sensors in detail. Then, we also discuss the different preparation methods of MXene‐based sensors, describe the classifications, and highlight the applications of MXene‐based flexible sensors in various scenarios. Finally, we identify the challenges that need to be overcome to accelerate the development of MXene‐based materials in flexible sensing. This review provides a comprehensive and systematic insight into MXene‐based flexible sensors and it is expected that this review will contribute to the development of higher performance MXene‐based flexible sensors.
Recent Progress in Light‐Scattering Porous Polymers and Their Applications
Authors: Yu Shudong , Chen Junchi , Gomard Guillaume , Hölscher Hendrik , Lemmer Uli 
Published: April 2023

AbstractConventional inorganic‐nanoparticles‐based scattering systems have dominated many practical applications for years. In contrast, the rise of porous polymers is perceived as a game‐changer due to their low cost, facile preparation, and great abundance. One challenging issue to be tackled is the design and fabrication of porous polymers with light‐scattering properties comparable to those of inorganic nanoparticles. Taking inspiration from nature (e.g., from white beetles Cyphochilus), scientists have achieved remarkable progress in the field of light‐scattering porous polymers and their related applications in recent years. Therefore, here, an up‐to‐date review about this emerging field is provided. This overview covers materials for making porous polymer structures, detailed fabrication methods, and applications benefitting from their tailorable light‐scattering properties. It is envisioned that more bioinspired light‐scattering porous polymers will be made to be potential alternatives of conventional nanoparticles‐based scatterers.