bluuebunny/crossref_metadata_2025_split huggingface dataset:
STOPP/START Anti-aggregation and Anticoagulation Alerts in Atrial
Fibrillation
Authors: Salis Francesco , Palimodde Antonella , Rundeddu Samuele , Mandas Antonella 
Published: May 2023

Background:
Atrial Fibrillation (AF) is common in the elderly. A key component of AF
management is Oral Anticoagulant Therapy (OAT), consisting of Vitamin K Antagonists (VKAs) or
Direct Oral Anticoagulants (DOACs). The aim of the present study is to check, using STOPP (Screening
Tool of Older Persons’ Prescriptions)/START (Screening Tool to Alert to Right Treatment) Criteria,
if such drugs are potentially inappropriately prescribed/omitted in an elderly population with AF, and to
determine their impact on mortality.

Methods:
This study included patients (n = 427) with nonvalvular AF consecutively evaluated between
2013 and 2019 at the Geriatric Outpatient Service, University Hospital of Monserrato, Cagliari, Italy,
and followed up for 36 months. The OAT group included 330 patients; the other 97 patients constituted
the non-OAT group. The sample was assessed for STOPP/START criteria.

Results:
We found no difference (p > 0.1) in comorbidity burden, frailty, and cardio-cerebro-vascular
disease prevalence in the two groups, which also did not present a difference in 36-month mortality (p =
0.97). OAT was overall appropriately taken, and 62.4% of OAT-group presented the START criterion
to take antiplatelets but also the STOPP criterion not to take them, because of the simultaneous anticoagulant
intake. In the non-OAT group, 69.1% presented the START criterion to take anticoagulants, and
21.6% the START criterion to take antiplatelets.

Conclusion:
Patients with AF are often prone to under or over-prescription, particularly of antithrombotic
drugs. The STOPP/START criteria are a valid tool to assess and correct wrong therapeutic choices.
In frail and comorbid subjects, survival is not correlated with the assumption of OAT.
Remimazolam and Remifentanil Use Induced Severe Respiratory Depression
and Laryngeal Spasm During Intravenous Sedation and Analgesia: A Case
Report
Authors: Xin Zhijun , Wang Ning , Wang Huaizhou 
Published: May 2023

Introduction:
Intravenous sedation and analgesia are widely used in minor surgeries.
Remifentanil and remimazolam are advantageous in this setting because of their rapid onset of
action, and short duration of action leading to a rapid recovery. However, the two drugs combined
need to be titrated to avoid airway-related adverse events.

Case Presentation:
This article reports a case of severe respiratory depression and severe laryngeal
spasm induced by remifentanil and remimazolam when they were used for analgesia and sedation
in a patient undergoing oral biopsy.

Conclusion:
We aim to improve awareness about the safety of these drugs among anesthesiologists
and increase their ability to manage the risk associated with their use.
Therapeutic Potential of Mesenchymal Stem Cells in PCOS
Authors: Nejabati Hamid Reza , Nikzad Sadeneh , Roshangar Leila 
Published: May 2023

Abstract:
Polycystic ovary syndrome (PCOS) is a major reproductive endocrine disorder affecting different
facets of a woman’s life, comprising reproduction, metabolism, and mental health. Recently, several
research groups have brought attention to the therapeutic capacity of mesenchymal stem cells (MSCs) for
the treatment of female reproductive disorders. It is highlighted that the treatment with bone marrow mesenchymal
stem cells (BMMSCs) considerably diminishes the levels of some inflammatory markers as
well as essential genes for ovarian production of androgens, which are considerably higher in theca cells
of PCOS women than in those of healthy cases. In addition, studies show that BMMSCs improve in vitro
maturation (IVM) of germinal vesicles (GVs) and the number of antral follicles while lessening the number
of primary and preantral follicles in mice with PCOS compared to healthy controls. Regarding adipose-
derived mesenchymal stem cells (AdMSCs), these cells restore the ovarian structure, enhance the
number of oocytes and corpora luteum, and diminish the number of aberrant cystic follicles in PCOS rats.
Some research also indicates that umbilical cord mesenchymal stem cells (UC-MSCs) alleviate the inflammation
of granulosa cells in women with PCOS. Therefore, due to the limited research on MSC therapy
in PCOS, in this review, we summarize the current knowledge on the therapeutic potential of three
types of MSCs: BMMSCs, AdMSCs, UC-MSCs and their secretome in the treatment of PCOS.
Changing Activism: Hal Baron Lays Out Strategy for Civil Rights in Public Housing
Authors: Barbour Katelyn , Ulbert Bridget , Suski Brody 
Published: May 2023

This issue of SourceLab introduces readers to Changing Activism: Hal Baron Lays Out Strategy for Civil Rights in Public Housing, a Civil Rights Era memorandum written by Hal Baron that argues for fair housing in Chicago.
This publication is part of the digital documentary edition series SourceLab, based at the University of Illinois at Urbana-Champaign. Our Editorial Board conducts rigorous peer-review of every edition.
BIOANALYTICAL METHOD VALIDATION FOR DETERMINATION OF ROSMARINIC ACID IN SIMULATED BIOLOGICAL MEDIA USING HPLC
Authors: CHOOLUCK KOTCHAPHAN , ROJSANGA PIYANUCH , PHECHKRAJANG CHUTIMA , JATURANPINYO MONTREE 
Published: May 2023

Objective: This study aims to develop and validate a simple, rapid and accurate HPLC method for the determination of rosmarinic acid (RA), an active marker of Thunbergia laurifolia (TL) tea, in Hank's Balanced Salt Solution (HBSS) using HPLC.
Methods: The separation was performed using a Xterra® C18 reversed-phase column (150 3.9 mm, 5 µm). The mobile phase consisted of 0.5% (v/v) glacial acetic acid (A) and acetonitrile (B). The flow rate was 1 ml/min and detection was carried out at 330 nm with UV-visible spectrophotometer. The method was validated according to the US FDA guidance on bioanalytical method validation in 2018.
Results: The method was successfully validated in the range of 50-500 ng/ml of RA. Intra-and inter-day precision ranged from 1.6 to 2.1% and 1.4 to 4.5%, respectively. Intra-and inter-day relative errors (% bias) were less than 7.6 and 3.6%, respectively. In addition, it was found that the stability of RA in HBSS could be dependent on the pH and temperature.
Conclusion: The developed method met the validation requirements and could be further applied to the permeability study of RA using an in vitro Caco-2 cell monolayer model.
Effect of the quality of orthodontic finishing on the stability of anterior tooth alignment
Authors: Mecenas Paulo , Cardoso Paula Coutinho , Maia Nair Galvão , Maia Francisco Ajalmar , Normando David 
Published: May 2023

ABSTRACT

Objectives
To evaluate whether the quality of orthodontic finishing influences long-term stability of anterior tooth alignment.

Materials and Methods
This retrospective study evaluated 38 patients. Data were obtained at the beginning of treatment (T0), at the end (T1), and at least 5 years after T1 (T2). At this point, the individuals were no longer wearing retainers. Anterior tooth alignment was measured using Little's index (LI). Effect on alignment stability was tested with multiple linear regression using LI–T0, LI–T1, intercanine width difference T1–T0, overbite (T1), overjet (T1), age, gender, time without retention, and presence of third molars as predictor variables. Well-aligned (LI &lt; 1.5 mm) and misaligned (LI &gt; 1.5 mm) cases were compared at T2.

Results
At T2, the alignment stability in the upper arch was inversely associated with the alignment quality (R2 = 0.378, P &lt; .001) and directly associated with overbite (R2 = 0.113, P = .008) at T1. Posttreatment changes caused cases finished with poor alignment to become similar to those finished with excellent alignment (P = .917). In the mandible, posttreatment changes were directly associated only with overjet (R2 = 0.152, P = .015) and well-finished cases displayed better alignment than poorly finished cases (P = .011). Other variables showed no significant association.

Conclusions
In arches without retention, better quality of orthodontic finishing does not guarantee the stability of anterior alignment. In the maxilla, long-term changes were more significant the greater the overbite and the better the quality of alignment at end of treatment. In the mandible, changes were not dependent on the quality of finishing but were associated with greater overbite at T2.
TINJAUAN TENTANG KINERJA KARYAWAN DILIHAT DARI PERSPEKTIF KECERDASAN EMOSIONAL, STRES KERJA, DAN KEPUASAN KERJA
Authors: Nainggolan Roma Novrianti , Duardji Dian Komarsyah , Efendi Nur 
Published: May 2023

This study aims to determine the effect of emotional intelligence, job stress, and job satisfaction on employee performance. This study uses a quantitative approach with the type of explanatory research. The sampling technique is non-probability sampling, with a sample of 85 respondents from Miss Cimory at PT Cimory Bekasi. The data was obtained from questionnaires which were distributed by using a Likert scale. This study used multiple regression analysis with SPSS 25 application for the data analysis tool. This study shows that partially, emotional intelligence and job satisfaction have a positive effect on employee performance. The work stress has a negative effect on employee performance. Simultaneously, there is an influence of emotional intelligence, job stress, and job satisfaction on employee performance. Performance and job satisfaction are variables that have characteristics in the very high category, especially regarding support from leaders and colleagues, as well as internal motivation due to job compatibility.
ABSTRAK
Penelitian ini bertujuan untuk mengetahui pengaruh kecerdasan emosional, stres kerja, dan kepuasan kerja terhadap kinerja karyawan. Penelitian ini menggunakan pendekatan kuantitatif dengan jenis penelitian explanatory research. Teknik pengambilan sampel yang digunakan adalah non-probability sampling, dengan sampel 85 responden Miss Cimory di PT Cimory Bekasi. Data diperoleh dari kuisioner yang disebar dengan menggunakan skala likert. Analisis data pada penelitian ini menggunakan analisis regresi linear berganda, dengan bantuan aplikasi SPSS 25. Penelitian ini menunjukkan bahwa secara parsial, kecerdasan emosional dan kepuasan kerja berpengaruh positif terhadap kinerja karyawan. Adapun stres kerja berpengaruh negatif terhadap kinerja karyawan. Secara simultan, terdapat pengaruh kecerdasan emosional, stres kerja, dan kepuasan kerja terhadap kinerja karyawan terhadap kinerja. Kinerja karyawan dan kepuasan kerja menjadi variabel yang memiliki penilaian dalam kategori sangat tinggi secara deskriptif, khususnya berkenaan dengan dukungan pimpinan dan rekan kerja, serta motivasi internal kecocokan terhadap karakter pekerjaan.
IDENTIFIKASI KOMPETENSI CUSTOMER SERVICE PADA BANK PERKREDITAN RAKYAT DENGAN METODE JOB COMPETENCY ASSESMENT (JCA)
Authors: Hapsari Marlinda Dini , Wulandari Jeni , Saptiani Fenny 
Published: May 2023

This study aimed to identify customer service competencies using the Job Competency Assessment (JCA) Method. This type of research uses a qualitative approach. Qualitative research obtains research subjects from informants using purposive sampling technique, namely the amount of information as much as 9 people according to selected criteria that are relevant to the research problem. Data analysis in this study was obtained from interviews, observation and documentation. At the interview stage the researcher used the Job Competency Assessment (JCA) Method to assess the competencies possessed by individuals. Based on the results obtained, it shows that there are 10 CS competencies in Bank Eka namely attention to clarity of tasks (attention to order), customer orientation (customer service orientation), enthusiasm for achievement (achievement orientation), self-control (self-control), impact and influence (impact and influence), empathy (interpersonal understanding), self-confidence (self-confidence), ability to direct (direction), special skills (personal expertise), cooperation (teamwork), 4 out of 10 competencies appears. The most concerned are clarity of tasks (attention to order), customer oriented (customer service oriented), passion for achievement (achievement orientation), self-control. This competency can later be more challenging, maintained and improved.
ABSTRAK
Penelitian ini bertujuan untuk mengidentifikasi kompetensi customer service dengan menggunakan Metode Job Competency Assesment (JCA). Jenis penelitian ini menggunakan pendekatan kualitatif, dengan jumlah informan sebanyak 9 orang yang ditentukan secara purposive. Teknik pengumpulan data menggunakan Behavioral Event Interview (BEI), observasi dan dokumentasi. Berdasarkan hasil penelitian, terdapat 10 kompetensi pada CS di BPR, dengan kompetensi prioritas pada kompetensi perhatian terhadap kejelasan tugas (concern for order), beriorientasi kepada pelanggan (customer service orientation), semangat untuk berprestasi (achievement orientation), pengendalian diri (self-control). Sementara kompetensi pendukung lain yakni kompetensi dampak dan pengaruh (impact and influence), empati (interpersonal understanding), percaya diri (self-confidence), kemampuan mengarahkan (directiveness), keahlian khusus (personal expertise), dan kerjasama (teamwork),
POTENSI TERJADINYA FINANCIAL DISTRESS DITINJAU DARI ASPEK KEPEMILIKAN SAHAM, STRUKTUR MODAL DAN UKURAN PERUSAHAAN
Authors: Romadona Retno , Damayanti Damayanti , Supriyanto Supriyanto 
Published: May 2023

Financial distress is a condition where the company's finances are in an unhealthy condition or crisis. Financial distress that continues to occur will result in the company going bankrupt. The purpose of this study is to examine and analyze the effect of shareholding, capital structure, and firm size on the potential for financial distress in retail trade companies listed on the Indonesia Stock Exchange for the 2015-2019 period. The data analysis technique used in this research is panel data regression analysis. Based on the results of the study indicate that the variables of managerial ownership, institutional ownership and capital structure have a significant effect on financial distress. While the firm size variable has no significant effect on financial distress. Simultaneously managerial ownership, institutional ownership, capital structure and firm size have a significant effect on financial distress.
ABSTRAK
Financial distress merupakan suatu kondisi dimana keuangan perusahaan berada pada kondisi yang tidak sehat atau krisis. Financial distress yang terus menerus terjadi akan mengakibatkan perusahaan mengalami kebangkrutan. Tujuan dari penelitian ini adalah untuk menguji dan menganalisis pengaruh corporate governance struktur modal dan ukuran perusahaan terhadap potensi terjadinya financial distress pada perusahaan retail trade yang terdaftar di Bursa Efek Indonesia periode 2015-2019. Metode analisis data yang digunakan dalam penelitian ini adalah analisis regresi data panel. Berdasarkan hasil penelitian menunjukkan bahwa variabel kepemilikan manajerial, kepemilikan institusional dan struktur modal memiliki pengaruh signfikan terhadap financial distress. Sedangkan variabel ukuran perusahaan tidak memiliki pengaruh siginifikan terhadap financial distress. Secara simultan kepemilikan manajerial, kepemilikan institusional, struktur modal dan ukuran perusahaan berpengaruh signifikan terhadap financial distress.
PENGARUH NON PERFORMING LOAN, OPERATING LEVERAGE, DAN FINANCIAL LEVERAGE TERHADAP KINERJA KEUANGAN PERUSAHAAN SEKTOR PERBANKAN YANG TERDAFTAR DI BURSA EFEK INDONESIA TAHUN 2016-2020
Authors: Sihaloho Ribka Rumiris , Suripto Suripto , Destalia Mediya 
Published: May 2023

This study aims to analysis whether or not there is an effect of non performing loans, operating leverage, and financial leverage on the financial performance of companies in the banking sector. This sampling technique in this study was using the purposive sampling method and obtained as many as 7 banking sector companies listed on the Indonesian Stock Exchange during 2016 to 2020. This study uses multiple regression analysis techniques panel data model with analysis tools using Eviews 11. The results of this study indicate that non performing loans have a positive and significant effect on the company’s financial performance, operating leverage has a positive and significant effect on the company’s financial performance, and financial leverage has a negative and insignificant effect on the company’s financial performance.
ABSTRAK
Penelitian ini bertujuan untuk menganalisis ada atau tidaknya pengaruh dari non performing loan, operating leverage, dan financial leverage terhadap kinerja keuangan perusahaan sektor perbankan. Teknik pengambilan sampel dalam penelitian ini yaitu menggunakan metode sampling purposive dan diperoleh sebanyak 7 perusahaan sektor perbankan yang terdaftar di Bursa Efek Indonesia selama tahun 2016 hingga 2020. Penelitian ini menggunakan teknik analisis regresi berganda model panel data dengan alat analisis menggunakan Eviews 11. Hasil dari penelitian ini menunjukkan bahwa non performing loan berpengaruh positif dan signifikan terhadap kinerja keuangan perusahaan, operating leverage berpengaruh positif dan signifikan terhadap kinerja keuangan perusahaan, dan financial leverage berpengaruh negatif dan tidak signifikan terhadap kinerja keuangan perusahaan.
ANALISIS DAMPAK COVID-19 TERHADAP ABNORMAL RETURN DAN TRADING VOLUME ACTIVITY
Authors: Panjaitan Priscilla Iranata 
Published: May 2023

This study aims to determine the stock market reaction to the Covid-19 event before and after the national announcement of the first Covid-19 case in 2020 in companies listed on the Indonesian stock exchange, the sub-sector of hotels, restaurants and tourism in Indonesia, whose differences are measured abnormally. return and trading volume activity. The sampling technique in this study used a purposive sampling method and obtained 38 companies that fit the criteria. The observation period was carried out for 30 days before the announcement and 30 days after the announcement. The type of data used is secondary data obtained from idx.co.id. The data analysis technique used is the Wilcoxon Signed Ranks Test and uses the SPSS 26 program analysis tool.The results of this study indicate that only 2 hypotheses have significant differences, this shows that the first Covid-19 case in Indonesia had no significant impact.
ABSTRAK
Penelitian ini bertujuan untuk mengetahui mengenai reaksi pasar saham terhadap peristiwa Covid-19 sebelum dan sesudah pengumuman nasional kasus pertama Covid-19 tahun 2020 pada perusahaan yang terdaftar di bursa efek indonesia sub-sektor hotel, restoran dan pariwisata di Indonesia, yang perbedaannya diukur dengan abnormal return dan trading volume activity. Teknik pengambilan sampel dalam penelitian ini menggunakan metode purposive sampling dan diperoleh 38 perusahaan yang sesuai dengan kriteria. Periode pengamatan dilakukan selama 30 hari sebelum pengumuman dan 30 hari setelah pengumuman. Jenis data yang digunakan adalah data sekunder yang diperoleh dari idx.co.id. Teknik analisis data yang digunakan adalah uji Wilcoxon Signed Ranks Test dan menggunakan alat analisis program SPSS 26. Hasil penelitian ini menunjukan bahwa hanya 2 hipotesis yang memiliki perbedaan yang signifikan, hal ini menunjukan bahwa adanya peristiwa kasus Covid-19 pertama kali di Indonesia tidak memberikan dampak yang signifikan.
KEPUTUSAN PEMBELIAN PRODUK KOSMETIK DAN ISU LINGKUNGAN
Authors: Herawati Desi , Ali Suprihatin , Adistya Diang 
Published: May 2023

The environment is becoming an important issue in companies today—not just products but also marketing processes and the company's commitment to actively participate in environmentally friendly campaigns. One of them is in cosmetic products. In particular, this study provides insight into the effect of green products, green advertising, and green trust on purchasing decisions for cosmetic products. The quantitative approach was applied to 100 samples selected purposefully. Multiple linear regression was used to analyze the data. The results of the study partially show that green advertising has a stronger influence than green products. However, there is no effect of green trust on purchasing decisions for cosmetic products. Aspects that are highly valued when choosing environmentally friendly cosmetic products are product safety, protecting the beauty of the earth, and participating in preserving the environment.
ABSTRAK
Lingkungan menjadi isu penting dalam perusahaan saat ini, tidak hanya sekedar produk, tetapi juga proses pemasaran dan komitmen perusahaan untuk berpartisipasi aktif dalam kampanye ramah lingkungan. Salah satunya pada produk kosmetik. Secara khusus studi ini memberikan wawasan mengenai pengaruh green product, green adverting, dan green trust terhadap keputusan pembelian produk kosmetik. Pendekatan kuantitatif diterapkan terhadap 100 sampel yang dipilih secara purposif. Data dianalisis menggunakan regresi linier berganda. Hasil penelitian secara parsial menunjukkan green advertising memberikan pengaruh yang lebih kuat daripada green product. Walaupun demikian, tidak terdapat pengaruh green trust terhadap keputusan pembelian produk kosmetik. Aspek yang dinilai tinggi untuk memilih produk kosmetik yang ramah lingkungan adalah keamanan produk, menjaga keindahan bumi dan ikut serta melestarikan lingkungan.
Comparison of genetic characteristics among species of Suaeda spp. (Amaranthaceae) in the western Anbar plateau - Iraq
Authors: Alrawi Sameer S. , Buniya Harith K. , AL-abide Naglaa M. M. 
Published: May 2023

Background: Comparison of genetic characteristics among species of Suaeda spp.
Objective: identifying the genetic characteristics among species Suaeda (Amaranthaceae) in Anbar Governorate. (From August 2020 to September 2021 fresh plant samples were collected in the flowering stage for the studied species).
Materials and methods: The genetic diversity of the Suaeda species was studied after DNA extraction and using the Inter Simple Sequence Repeats Reaction method to recorded in the genetic aspects. DNA was extracted from young leaves of the studied species. The concentration and purity of the DNA were determined, and the detection of genetic relationships between the studied plant species as well as finding this genetic fingerprint by ISSR Reaction.
Results: The results showed that the plant samples collected during study belong to species of the genus Suaeda, and these species were: S. aegyptiaca, S. altissima, S. carnosissma, S. fruticosa, S. monoica, S. vera and S. vermiculata symbolized by (S1, S2, S3, S4, S5, S6, S7) respectively for the purpose of brevity. The results showed that there was the highest close between S. aegyptiaca and S. vera which amounted to 0.6319, and the results showed that there was the least closeness between S. aegyptiaca and S. carnosissma which amounted to 0.4231.
Conclusion: Genetic traits are among the stable traits that can be adopted in separating the studied species. The genetic study, especially at the DNA level, is one of the most important modern taxonomic studies that rely on PCR technology for the accuracy of its results and the speed of obtaining results.There are at least seven species of the genus Suaeda in the western province of Anbar Governorate - Iraq.