bluuebunny/crossref_metadata_2025_split huggingface dataset:
Compliance in Review Attendance among Orthodontic Patients attending a Tertiary Level Health Care Centre
Authors: Temisanren O.T. , Ifesanya J.U. , Olatunji A.B. 
Published: August 2023

Objectives: Estimating patient compliance during orthodontic treatment cannot be overemphasized as timely and successful outcome of orthodontic treatment is dependent on it. This study assessed patients' compliance to orthodontic reviews at a tertiary care orthodontic clinic as well as explored various factors that may influence review attendance.Materials and Methods: Data were collected retrospectively from 133 patients' case notes as well as the clinic daily attendance records. Socio-demographic data and type of appliance used by patients was extracted. The pattern of punctuality (in days) to clinic attendance as prescribed by the managing orthodontist was also ascertained. Data were analysed using the SPSS version 22. Level of significance was set at p<0.05.Results: The mean age was 14.65 ± 5.98 years. Sixty-two (46.6%) patients were males while 71(53.4%) were females. Sixteen patients (12%) had removable appliances, 116(87.2%) had fixed appliances while only one person (0.8%) had both fixed and removable appliances. Eighty (60.2%) attendees were resident within the state of the clinic's location while 53 (39.8%) resided outside the state. At the first review visit after treatment commenced, 92(69.2%) presented on time for review while 41 (30.8%) defaulted with a mean lag time of 49.0±49.0 days before presenting at the clinic. The total default time varied significantly with the number of visits and length of treatment time (p<0.001).Conclusion: Rate of default to orthodontic reviews was found to increase gradually from the 2nd visit and imparted negatively on treatment time.
Influence of Dental Education on the Perception of Dental Aesthetics among Undergraduate Dental Students in a Nigerian University
Authors: Ameh G.G. , Enabulele J.E. 
Published: August 2023

Background: Literature has shown the existence of difference in perception of esthetics between dentists and lay people. Could this difference be attributable to undergraduate dental education? This study aims to determine the influence of dental education on the relative perception of dental aesthetics among undergraduate dental students.Materials and methods: A cross-sectional study was carried out amongst all dental students attending a Nigerian University. The dental aesthetics selfperception questionnaire originally designed by Goldstein was administered to subjects. The data were subjected to descriptive analysis. Independent sample t-test and one-way analysis of variance were used to compare means across groups. Due to the multiple comparisons a post-hoc test (Bonferoni) was carried out with the one-way analysis of variance. Chi square was used to determine association between variables with p set at 0.05.Results: A total of 132 students participated in the study. Majority (91.7%) were self-confident about smiling. More than half (54.5%) of the respondents believed there was someone with a better smile. With regards to wish of whiter teeth, 67.4% wished their teeth were whiter. The aesthetic self-perception scores of the respondents ranged from 0-12 with a mean score of 4.28± 2.64. There was no statistically significant association between the mean aesthetic self-perception score and the level of study of the participants.
Conclusion: A positive aesthetic self-perception was observed in dental students when it comes to their smile. However, there was no statistically significant association between the level of study of the respondents and the self-perception of dental student.
Immediate Hypersensitivity Reaction to Composite Restorations
Authors: Oderinu O.H. , Makinde O.E. 
Published: August 2023

Restorative materials used in dentistry are constantly exposed to salivary components like enzymes that have a high impact on the degradation of these materials and subsequent leaching of some of their constituents which may be harmful to the oral tissues in some patients. Released triethyleneglycolmethacrylate, bisphenol A-glycidyl methacrylate (Bis-GMA), diurethanedimethacrylate (UDMA) and formaldehyde have been detected from incompletely polymerized composite and are implicated in occurrence of various adverse reactions. We present a case of a 60 year old female who had composite restorations done. She later presented with complaints of several episodes of intermittent gingival and cheek swellings of sudden onset adjacent to the restored teeth. The filling was taken off and patient was placed on anti-allergy medications with a close follow-up. This presentation highlights the occurrence of a typical allergy to composite material in our centre. It serves to educate dental practitioners about the awareness of such adverse reactions to dental resin materials and the need to be prompt in management of the condition.
Fibrous Dysplasia and Ossifying Fibroma - Solving the Diagnostic Dilemma
Authors: Soyele O.O. , Gbotolorun M.O. , Braimah R.O. , Taiwo A.O. , Ibikunle A.A. 
Published: August 2023

Fibrous dysplasia (FD) and Ossifying fibroma (OF) of the jaws belong to a group of lesions called benign fibro-osseous lesions of the craniofacial skeleton (BFOL). This group of intraosseous disease processes which are comparable in their microscopic features are characterized by hypercellular fibroblastic stroma containing various combinations of bone or cementum-like tissue and other calcified structures. Of these lesions, FD and OF are the most closely related, and although FD is recognized as a harmatomatous lesion and OF a tumour, these lesions are difficult to distinguish both clinically and histologically from each other. This review of current literature aims to highlight emerging features clinically, genetically and histologically that can help in distinguishing these two lesions.
AMELOBLASTOMA WITH INFRATEMPORAL EXTENSION: A REVIEW OF LITERATURE
Authors: Oyeneyin Aliyu Ope , Adekunle Adegbayi 
Published: August 2023

Ameloblastomas are benign tumors of odontogenic epithelium. They are locally aggressive with tendency to recur and sometimes with metastatic behavior. Recurrences often occur due to incomplete treatment and they can occur at difficult sites such as temporal and infratemporal fossa. Recurrences in the temporal area are very rare and are related to the type of primary treatment.
AIM: This literature review aims to answer the question on how common recurrent ameloblastoma entends to the infratemporal fossa and how this is related to the site of the primary lesion.
METHODS; Web search for case reports, case series of ameloblatoma with temporal, infratemporal extension, published in the English literature was carried out. Search results were further scrutinized for age, sex, location of lesion, histology, treatment modalities and recurrence following the adopted treatment modalities and treatment outcome.
RESULT; A total 15 full length articles were included in this study. Twelve were case reports and 3 were case series. Of 28 patients with ameloblastoma in the articles, only 22 were recorded to have presented with ameloblastoma with infratemporal or temporal fossa involvement. All the cases of ameloblastoma involving the infratemporal/temporal fossa were recurrent tumors and the average time from first surgical intervention to recurrence was 11.36 years. Most of the primary cases were seen in the mandible (73%) with body/ramus region being the commonest location. Only 5cases were reported to be primarily maxillary ameloblastoma.
CONCLUSION; This review has shown that temporal/infratemporal extension of ameloblastoma occurs commonly with recurrent lesions, although the overall reported incidence is relatively low. Aggressive primary tumor resection, especially for extensive mandibular lesions may be key to preventing this tumor extension.
`PATTERN OF HISTOLOGIC VARIANTS OF AMELOBLASTOMA IN A SECONDARY HEALTH CARE FACILITY IN LAGOS STATE: A 5-YEAR RETROSPECTIVE STUDY.
Authors: Castano Babalola , OLUWAKUYIDE Remilekun T , ADESHINA Oluwafemi A , Adenaike Funmi S , Ayodele Adeshina , Osobu Oluwatosin , Adegbesan Kayode , Faminu Edward 
Published: August 2023

Background: Ameloblastoma is a benign epithelial odontogenic neoplasm which is common amongst the Yoruba ethinc group. The various histologic types have been elucidated.
Aim: This study aimed to assess the prevalent histologic types of ameloblastoma in a Lagos secondary health care facility.
Methodology: A 5-year retrospective review of histopathologically diagnosed slides were retrieved. Data extracted include the age, gender, location, ethnicity and histologic variants were analysed by SPSS version 26. Percentages, ratio, mean, standard deviation and crude odd ratio were determined, and p-value ⩽ 0.05 is considered significant.
Result: A total of seventy-seven histopathologically diagnosed ameloblastoma slides were retrieved. Males were more affected than females in ratio 1.2:1 with the mean age 33.61±13.3. Ameloblastoma was commonest in the third decade of life and more in the mandible than maxilla. Yoruba ethnic group was most affected. The commonest histologic type was the unicystic type with intraluminal subtype accounting for the largest proportion. There was significant association between histologic types and gender (p= 0.037). Crude odd ratio revealed the odds in the unicystic type between male and female {p=0.041; CI=95%, OR=2.649(1.042-6.733)} and in the follicular between male and female {p=0.013; CI=95%, OR=3.855(1.321-11.288)}.
Conclusion: The unicystic histologic type of ameloblastoma was the commonest, occurring more in females and this was followed by the follicular histologic type which occurred more in males in this Lagos State secondary health care facility.
The Role of Clinical Pharmacists in Patient-Centric Comprehensive Multiple Sclerosis Care
Authors: Bainbridge Jacquelyn , Barnhart Rebecca , Fuller Ryan , Hellerslia Van T. , Kidd Julie , Merrill Steven , Volger Emily , Montgomery Jenelle H. 
Published: August 2023

ABSTRACT

BACKGROUND:
Individuals with multiple sclerosis (MS) may experience a variety of visible and invisible symptoms and, as they age, comorbidities related and unrelated to their MS. This can result in a complex medication regimen that includes disease-modifying therapies, symptom management drugs, and prescriptions for other comorbid disorders.

METHODS:
We reviewed the existing literature to discover how to optimally integrate neurology clinical pharmacists into the MS care team and how clinical pharmacists can directly support both providers and patients through their expertise in pharmacology and medication management.

RESULTS:
With approaches founded on a shared decision-making process alongside neurology providers, patients, and care partners, clinical pharmacists can help meet the complex challenges of MS care in a variety of ways. Especially within MS clinics, they are well positioned to enhance current neurology practices given their extensive training in comprehensive medication management and their ability to identify nuances in medication management to promote pharmacovigilance and patient-centered care.

CONCLUSIONS:
Neurology clinical pharmacists bring multifaceted medication management and patient counseling and education skills to the MS care team and can support the shared decision-making process by serving as an accessible resource for patients and clinicians. By building trusted partnerships between neurology providers and clinical pharmacists, MS care teams can achieve effective and efficient patient care. Future research should compare clinical and patient-reported outcomes between patients receiving standard care and those receiving multidisciplinary, pharmacist-integrated care.
Integrated lipidomic and transcriptomic analysis reveals diacylglycerol accumulation in olive of Longnan (China)
Authors: Hu Wei , Ma Junyi , Zhang Hongjie , Miu Xin , Miao Xin , Deng Yu 
Published: August 2023

Background
Olive (Olea europaea L.) oil accumulate more diacylglycerols (DAG) than mostly vegetable oils. Unsaturated fatty acids-enriched DAG consumption enhanced wellness in subjects. However, the mechanism of DAG accumulation is not yet fully understood.

Methods
In this study, gene network of DAG accumulation and fatty acid composition in the two olive mesocarps (“Chenggu 32” (CG) and “Koroneiki” (QJ)) were investigated by integrating lipidome and transcriptome techniques.

Results
A total of 1,408 lipid molecules were identified by lipidomic analysis in olive mesocarp, of which DAG (DAG36:3, DAG36:4 and DAG36:5) showed higher content, and triacylglycerols (TAG54:3, TAG54:4) exhibited opposite trend in CG. Specifically, DAG was rich in polyunsaturated fatty acids (especially C18:2) at the sn-2 position, which was inconsistent with TAG at the same positions (Primarily C18:1). Transcriptomic analysis revealed that phospholipase C (NPC, EC 3.1.4.3) were up-regulated relative to QJ, whereas diacylglycerol kinase (ATP) (DGK, EC 2.7.1.107), diacylglycerol acyltransferase (DGAT, EC 2.3.1.20), and phospholipid: diacylglycerol acyltransferase (PDAT, EC 2.3.1.158) were down-regulated.

Conclusion
We speculated that the non-acyl coenzyme A pathway played a significant role in DAG biosynthesis. Additionally, fatty acyl-ACP thioesterase B (FATB, EC 3.1.2.14), stearoyl [acyl-carrier-protein] 9-desaturase (SAD, EC 1.14.19.2) and omega-6 fatty acid desaturase (FAD2, EC 1.14.19.6) were highly expressed in CG and may be involved in regulating fatty acid composition. Meanwhile, phospholipase A1 (LCAT, EC 3.1.1.32) involved in the acyl editing reaction facilitated PUFA linkage at the sn-2 position of DAG. Our findings provide novel insights to increase the DAG content, improve the fatty acid composition of olive oil, and identify candidate genes for the production of DAG-rich oils.
Superoxide dismutase ameliorates oxidative stress and regulates liver transcriptomics to provide therapeutic benefits in hepatic inflammation
Authors: Chen Longyan , Liu Yang , Zhang Yonggang , Zhang Yanmin , Wang Wei , Han Hongyu , Yang Chunyu , Dong Xueqian 
Published: August 2023

Background
Oxidative stress refers to the imbalance between oxidants and antioxidants in organisms and often induces hepatic inflammation. Supplementing exogenous superoxide dismutase is an effective way to alleviate oxidative stress; however, the effects and mechanisms by which superoxide dismutase alleviates hepatic inflammation remain unclear.

Methods
This study established a Kunming mouse model to verify and investigate the oxidative stress and hepatic inflammation-alleviating effects of the superoxide dismutase oral supplement that was prepared by our research group in a previous study.

Results
The superoxide dismutase product significantly restored the body weight and liver alanine transaminase, aspartate aminotransferase, superoxide dismutase, catalase, glutathione, and glutathione peroxidase levels of oxidative stress induced mice. Moreover, exogenous superoxide dismutase significantly inhibited interleukin 1β and interleukin 6 mRNA expression in the livers of mice with hepatic inflammation. Transcriptomic analysis indicated that superoxide dismutase had a significant inhibitory effect on Endog expression, alleviating oxidative stress damage, and mediating liver cell apoptosis by regulating the expression of Rab5if, Hnrnpab, and Ifit1.

Conclusion
Our research verified the oxidative stress remediation effects of superoxide dismutase and its therapeutic role against hepatic inflammation. This study can lay a foundation for investigating the mechanism by which superoxide dismutase alleviates hepatic disease.
The moderating and mediating effects of personality on the association between morningness and well-being
Authors: Lee Soo Jin , Jeong Sudong , Chae Han 
Published: August 2023

BackgroundMorningness (morning-eveningness preference or chronotypes) and personality can be both associated with well-being, but few studies have directly compared these two constructs as correlates of well-being. Thus, the first purpose of this study was to test the effects of interactions between stable personality traits (temperaments) and morningness on well-being. Furthermore, personality factors are often composed of both stable biological factors (temperament) and socio-cultural factors (character), and little is known about personality interplay of temperament and character factors with respect to morningness and well-being. The second purpose of this study was therefore to examine the sequential mediating effects of temperament and character factors on the relationship between morningness and well-being.MethodsThe Composite Scale of Morningness, the Korean version of the Temperament and Character Inventory-Revised Short Version (TCI-RS), and the Satisfaction with Life Scale were used to measure morningness, personality dimensions, and well-being, respectively, in 287 Korean university students. Moderating and sequentially mediating effects of temperament and character traits were determined using Hayes’ PROCESS macro in SPSS after controlling for sex and age.ResultsFirst, novelty-seeking (NS) and persistence (PS) temperaments have demonstrated the moderating effect in the association between morningness and well-being. The positive effects of morningness on life satisfaction increased with lower NS and PS, respectively. However, other temperaments such as harm avoidance (HA) and reward dependence (RD) have not shown the moderation in the relationship between morningness on well-being. Second, HA temperament and self-directedness (SD) character sequentially mediated the relationship between morningness and well-being. The combination of low scores of HA and high scores of SD have shown the positive effect on the relationship between morningness and well-being.DiscussionThis study demonstrated that both the interactions between temperaments and morningness, and combination of specific TCI-RS temperament and character traits play important roles in influencing the association between morningness and well-being. The significance of the mature SD character and its implications for well-being are discussed with limitation of the present study.
Screening of Mustard Varieties for Resistance against Mustard Aphid, (Kaltenbach)
Authors: Chand Amar , Khinchi S. K. , Redhu Mandeep , Arvind  , Choudhary Renu , Choudhary Arjun , Nayak Rohit Kumar 
Published: August 2023

The present investigation was conducted at Agronomy Farm and Laboratory, Department of Biochemistry, S.K.N. College of Agriculture, Jobner (Rajasthan) during Rabi, 2019-20 and Rabi, 2020-21 to screen out the varieties of mustard for their resistance to mustard aphid, Lipaphis erysimi. The overall pooled mean aphid population ranged from 42.99 to 80.55 per 10 cm terminal shoots of five plants on different varieties. The minimum aphid infestation (42.99 aphids/ 10 cm terminal shoot) was recorded on Varuna followed by Bio-902 (44.63 aphids/ 10 cm terminal shoot) and both were found statistically same in reaction to aphid incidence. The maximum infestation/ 10 cm terminal shoot was recorded on Kranti (80.55 aphids) followed by GM-2 (79.99 aphids), and RH-30 (79.46 aphids) which remained at par to harbour the aphid population. The variability of resistance in mustard varieties in the decreasing order was Varuna, Bio-902, NRCDR-2, Pusa Bold, Laxmi, NRCHB-101, Rohini, Durgamani, Vardan, RH-9304, GM-1, Maya, RH-30, GM-2 and Kranti. The statistical characterization of results revealed that out of fifteen mustard varieties, two varieties Varuna and Bio-902 were found less susceptible to the mustard aphid, L. erysimi. Nine varieties viz., NRCDR-2, Laxmi, Pusa Bold, NRCHB-101, Rohini, Vardan, RH-9304, Durgamani and GM-1 were categorized as moderately susceptible, whereas, four varieties viz., Maya, RH-30, GM-2 and Kranti were categorized as highly susceptible in both years of the study.
Headpulse Biometric Measures Following Concussion in Young Adult Athletes
Authors: Halabi Cathra , Norton Lynda , Norton Kevin , Smith Wade S. 
Published: August 2023

ImportanceConcussions are common in sports. Return-to-play protocols can be enhanced by objective biometrics.ObjectiveTo characterize temporal changes of headpulse, a digital biometric, in athletes with sports-related concussion; to explore the association of unstructured physical activity with headpulse changes.Design, Setting, and ParticipantsThis cohort study included headpulse measurements from players in the highest level of amateur Australian Rules Football in South Australia. Analysis included feasibility and validation phases, with the feasibility cohort recruited between August 5, 2021, and September 10, 2021, and the validation cohort recruited between May 5, 2022, and September 3, 2022. Data were analyzed October 2022 through January 2023.InterventionsCranial accelerometry detected micromovements of the head following cardiac contraction (what we have described as “headpulse”). Headpulse was serially recorded for 1 month in concussed individuals.Main Outcomes and MeasuresHeadpulse waveforms underwent frequency transformation analysis per prespecified algorithm. Result Z scores were calculated. Headpulse Z scores exceeding 2 (2 SDs from control means) met an abnormality threshold. Headpulse sensitivity, timing, and duration of change were determined.ResultsA total of 59 control and 43 concussed individuals (44 total concussions; 1 control also concussed, 1 concussed individual injured twice) provided headpulse measurements. The feasibility cohort (all male) included 17 control (median [IQR] age, 23 [19-28] years) and 15 concussed individuals (median [IQR] age, 21 [19-23] years). The validation cohort included 25 female (median [IQR] age, 21 [20-22] years) and 17 male (median [IQR] age, 26 [23-29] years) control individuals, and 8 female (median [IQR] age, 28 [20-31] years) and 20 male (median [IQR] age, 21 [19-23] years) concussed individuals. Headpulse reached abnormality threshold in 26 of 32 concussed individuals (81%; 9% on day 0, 50% by day 2, 90% by day 14). Headpulse alterations lasted 14 days longer than symptoms and were exacerbated by return-to-play or unsupervised physical activity.Conclusions and RelevanceIn this study of 101 amateur Australian Rules Football athletes, the digital headpulse biometric was evaluated in 44 sports-related concussions. Compared with controls, new headpulse changes occurred after concussion; this objective metric may complement return-to-play protocols.