bluuebunny/crossref_metadata_2025_split huggingface dataset:
Memprediksi Kawasan Rawan Banjir Berdasarkan Luas Daerah Genangan Banjir di Kota Samarinda
Authors: Sundari Yayuk Sri 
Published: April 2023

ABSTRACTChanges in land use patterns affect the potential decline in the region caused by the increasingly widespread use of land for building. which caused a reduction in water catchment areas occurrence inundation or flooding. The purpose of this study was to predict the flood prone areas in the subzone Karang Mumus. Results are expected to be known biophysical subzone Karang Mumus subzone. Analysis region extensive flooding subzone Karang Mumus of 80.48%, topography of hilly and flat areas in particular there are in the groove river Karang Mumus. Slope is a factor that has a major effect on the level of vulnerability to flooding. Land use affects the determination of the flood prone areas, land use relates to the size of the water runoff. Biophysical conditions in subzone Karang Mumus for the district that are prone to flooding, District of North Samarinda flat slope of 0-8% with an area of 12356.3 hectares of 31.0265%, 25-40% slope class steep slope with a spacious 269.2 hectares area of 0.6760%, slope>40% grade incline is very steep with an area of 12.7 hectares of 0.0319%. For closure / shrub land use 12700.7 hectares of 31.8913%, the mining area of 4.0864% 1627.4 hectares , with an area of 1814.9 hectares settlement amounted 4,557,2%, open land with an area of 781.5 hectares amounting to 1.9623%, with an area of forest land cover 47.1 hectares of 0.1183% and a vast pool of 1,506 hectares of 55.72%.Keywords: slope, flood prone areas, extensive flooding.
An Analysis of Al-Djurjani’s Definition of Identity – huwiyya: The then and Now
Authors: Gokcekuyu Ertugrul 
Published: April 2023

Purpose - This paper aims to answer in what ways such an early account of huwiyya may overlap or have similarities with some of the modern, yet ambiguous depictions of the term.
Design/methodology/approach - The research design is descriptive-qualitative research. The data gained are written words and sentences from al-Djurjani’s works.
Findings - Literature today acknowledges more progressive interpretations of identity, wherein the phrase has been used in ambiguous ways, categorizing the individual in existential, contextual, and perceptual terms attempting to understand the inner and outer workings of the Self. Most definitions of identity in social sciences assume the phrase to be a unit of analysis; a challenging task when the phrase is so heterogeneous. The point of departure in this article is Al-Djurdani’s two-layered live wire definition that connotes a binary reading. While the first layer of this - one of the earliest - Muslim philosophical definitions is existentialist, the second layer merits a reading that is modestly contextual.
Originality/value - The point of departure in this article is Al-Djurdani’s two-layered live wire definition that connotes a binary reading. While the first layer of this - one of the earliest - Muslim philosophical definitions is existentialist, the second layer merits a reading that is modestly contextual.
Paper type – Concept paper
Do we know the normal anterior-posterior diameters of the spinal cord and canal in newborns?
Authors: ÖZBEY Öner , ARSLAN Fatma Zeynep , KÖREZ Muslu Kazım , PAYASLI Müge 
Published: April 2023

Aim: We aim to reveal the normal anterior-posterior diameter of the spinal cord and canal at cervical, thoracic and lumbar levels in newborn with sonographic measurements and to create a reference value. Also, we aim to reveal whether the anterior-posterior diameter at these levels will vary with the newborn's head circumference, gender, height and weight. Thus, we aim to be one of the pioneering studies in the literature
Material and Method: Statistical analysis was performed to determine normal anterior-posterior diameter for the spinal canal and spinal cord at each vertebral level, and their correlations with birth weight, length and head circumference.
Results: 188 newborns were included. The mean anteroposterior spinal canal diameter in male newborns was significantly higher compared to females (9.27±0.83 vs 9.00±0.79, p=.020). There was a positive correlation between spinal cord anterior-posterior diameter and head circumference at thoracic level, which was statistically significant. There was a positive correlation between spinal canal diameter and height at thoracic level. There was a positive correlation between spinal canal diameter and weight at lumbar level.
Conclusion: The establishment of the normal values for anterior-posterior diameters of the spinal cord in healthy newborns may contribute the current literature data.
Can asymptomatic SARS-CoV-2 infection cause spontaneous abortion?
Authors: BENDER Rukiye Ada , AKBULAK Renginar , SENGUL Ali 
Published: April 2023

Aim: The probability of spontaneous abortion is known to increase (15%) in the pregnant women who develop symptomatic and even “Severe Acute Respiratory Syndrome (SARS)” due to maternal infections. It is known that the SARS-CoV-2 virus, one of these infectious agents, enters host cells by binding to angiotensin-converting enzyme 2 (ACE2). New literature data have shown the increased ACE2 receptor in the endometrium during the decidualization phase and the ability of SARS-CoV-2 to enter endometrial stromal cells through ACE2 proteins. This shows that the COVID-19 infection can cause many pathologies such as early pregnancy loss. The aim of this study is to investigate the effects of SARS-CoV-2 virus which are positive in the uterine samples on pregnancy loss.
Material and Method: 13 women who had first trimester pregnancy loss were included in this cross-sectional study. None of these pregnant women had any known symptoms of SARS-CoV-2 infection. SARS-CoV-2 infection was screened in uterus and naso-oropharynx samples by real-time polymerase chain reaction (RT-PCR) test in these pregnant women. Women with positive RT-PCR results will be evaluated for pneumonia by lung tomography. It is planned to evaluate the sample taken from the naso-oropharynx in the partners of these women for SARS-CoV-2 infection by RT-PCR. In addition, in positive cases, RT-PCR was planned from the uterus and naso-oropharynx samples at 7-day intervals until the case turned negative.
Results: RT-PCR test for SARS-CoV-2 was positive only in a sample taken from the uterus of one woman (7.6%). The naso-oropharyngeal sample of the same patient was negative, and the patient had no symptoms of COVID-19. No COVID-19-related lesion was observed in the lung tomography of this patient. The results of the RT-PCR test performed 7 days later with samples taken from the uterus and naso-pharynx were also negative. After the patient's positive RT-PCR result, a naso-oropharyngeal sample was taken from his partner. The RT-PCR test result for SARS-CoV-2 in the patient's partner was negative.
Conclusion: The fact that the SARS-CoV-2 virus was negative in the naso-oropharyngeal sample and positive in the uterine sample in a pregnant woman who had a miscarriage suggests that the endometrium may be an entry route for the virus. These data suggest that the virus can lead to adverse pregnancy outcomes, including early pregnancy loss, even without known symptoms. A large number of studies are needed to evaluate the effects of common viruses on pregnancy beyond the expected and defined symptoms.
Evaluation of polysomnography changes in patients using antidepressants
Authors: KARA Mehmet , KILIÇ Soner 
Published: April 2023

Aim: In patients followed up with sleep disorders and receiving antidepressant treatment, the choice of antidepressant should be appropriate to the characteristics of the patient and the drug. The aim of this study is to show the effects of antidepressant drug selection on polysomnography results.
Material and Method: This study was planned retrospectively and was conducted by scanning patient files. Between 01.06.2018 and 01.06.2022, the files of patients who underwent polysomnography in the sleep laboratory of our hospital and were using antidepressants were scanned. Differences between antidepressant groups and polysomnography results were analyzed with IBM SPSS v23.
Results: 103 patients (43 women/60 men) were included in the study. It was determined that 56 of these patients used selective serotonin reuptake inhibitors and 47 of them used serotonin and norepinephrine reuptake inhibitors. Yates correction was used in the comparison of gender according to the groups, and there was no statistically significant difference between the distributions of gender according to the groups (p=0.248). According to the drug groups, the results of the polysomnography examined in the study do not differ according to the groups.
Conclusion: It was shown that the antidepressant groups examined in the study did not differ in terms of affecting the results of polysomnography. Other clinical characteristics of the patient can be taken into account in the selection of antidepressants in these groups.
Does adolescent pregnancy affect postmenopausal bone mineral density?
Authors: ADIGÜZEL Cevdet , SEYFETTİNOĞLU Sevtap 
Published: April 2023

Aim: This study aims to investigate the effect of adolescent pregnancies on bone mineral density in the postmenopausal period and to contribute to this controversial issue.
Material and Method: Our study included 70 women at postmenopausal ages. The participants were divided into two groups. Thirty-five women with a history of pregnancy in adolescence were considered group 1, and 35 women without a history of pregnancy were considered group 2. The BMD was measured in the total hip, femoral neck, and lumbar spine. The data were compared using SPSS version 26, and p
Short-term effects of horizontal muscle operations on anterior and posterior segment parameters in strabismus patients
Authors: SOYDAN Adem , KAYMAZ Abdulgani , KILIÇ ÜÇGÜL Rukiye , ULAŞ Fatih , ÇELEBİ Serdar 
Published: April 2023

Aim: To evaluate the short-term effects of horizontal muscle resection (Rt) or recession (Rs) surgeries on anterior and posterior segment parameters (ASPs and PSPs) in strabismus patients, using Pentacam HR and optical coherence tomography (OCT) devices.
Material and Method: This prospective study included 21 female and 17 male patients who underwent horizontal muscle surgery (Rt or Rs). ASPs were evaluated with Pentacam HR and PSPs were evaluated with OCT, one day before and one month after surgery.
Results: The mean age of all the patients included in the study was 16.52±7.90 years. Rt surgery was performed on 18 patients and Rs surgery on 20 patients. When the pre- and postoperative measurement values of all patients were compared, statistically significant differences were found in respect of iridocorneal angle (ICA) 90° and anterior chamber depth (ACD) in both the Rt and Rs groups. A significant narrowing was detected in ICA 90° and ACD in Rt patients (p
A biomarker predicting unfavorable prognosis in malignant pleural mesothelioma: systemic immune–inflammation index
Authors: BAYKAL Hüsnü , ÇİMEN Filiz 
Published: April 2023

Aim: Malignant pleural mesothelioma (MPM) is an extremely mortal condition. Only a few prognostic biomarkers have been described for MPM. Our study looked into the association between patient survival and the Systemic Immune Inflammation Index (SII).
Material and Method: A total of 158 patients who were admitted to our hospital between January 2013 and December 2022, and had a histopathologically confirmed diagnosis of MPM were included in the study. Before treatment, hematological parameters and SII were determined. A Spearman's correlation analysis was performed to analyze the correlation of mean survival with hematological parameters.
Results: The study involved 158 patients in all. 70 patients had a history of smoking, the median age was 63 years, the mean survival time was 15.3 months, and 57.6% of the participants were men. The epithelioid type (84.2%) was the most prevalent histological subtype, and 29 patients had stage 4 illnesses. Of the participants, 84% had received chemotherapy, and 22% had received radiotherapy before. Among the 39 patients who had surgery, 5 had an extrapleural pneumonectomy. SII mean±sd was (1427.2±1207.3). The patients with stage 4 disease had significantly shorter survival (p=0.001). The patients who had surgery survived significantly longer (p=0.01). Hemoglobin (Hb) (r:0.21, p:0.01) and Hematocrit (Hct) (r:0.18, p:0.03) values showed weak positive correlations with mean survival. It was evident that mean survival got shorter as SII (r:-0.17, p:0.04) and neutrophil-lymphocyte ratio (NLR) (r:-0.19, p:0.02) values got higher. On the other hand, there was a strong positive association between mean survival and the lymphocyte-monocyte ratio (LMR) (r:0.21, p:0.01). When the parameters that had statistically significant differences among the groups were taken as control variables and the statistical analysis was re-performed, it was found that Hgb and Hct values as well as NLR and LMR ratios lost their significant correlations with survival. However, the SII ratio was still negatively correlated with survival (r:-0.16, p:0.04).
Conclusion: Pretreatment SII is a noninvasive and easy-to-calculate biomarker that predicts the prognosis of MPM. It is negatively correlated with mean survival regardless of the tumor stage and surgical management.
Investigation of the effect of age-related hearing loss on visual memory
Authors: ATİLLA Mahmut Huntürk 
Published: April 2023

Aim: To investigate the effect of age-related hearing loss on visual memory.
Material and Method: 20 participants with normal hearing loss and 38 participants with hearing loss were included in the study. All of the patients were older than 65 years. Pure tone audiometry, speech audiometry and Benton visual retention test were applied to all participants.
Results: Mean Benton test score of the hearing-normal and the hearing loss group were 13.10±1.48 and 8.81±3.27 respectively. Patients were divided into three groups as hearing-normal, hearing loss with WRS greater than 80% and hearing loss with WRS lower than 80%. In terms of Benton scores there was statistically significant difference between groups (p
Changes in nasolabial angle may alter nasal valve morphology and airflow: a computational fluid dynamics study
Authors: ERDOĞAN Mehmet Mustafa , UĞUR Levent 
Published: April 2023

Aim: Nasal valve (NV) dysfunctions are a significant cause of nasal obstruction. Changes in the nasolabial angle (NLA) may also cause changes in NV morphology. The effect of changes in the 3D structure of the nasal valve region (NVR) on nasal airflow has yet to be studied sufficiently. The accuracy of computational fluid dynamics (CFD) simulation results of nasal airflow has been confirmed by in vitro tests. Therefore, this study aimed to evaluate the effect of changes in NV structure and volume on nasal airflow based on the CFD method.
Material and Method: We used CT images to create a 3D structural model of the NVR. First, CT images were transferred to MIMICS® software, and the nasal air passage was modeled. A solid reference model of the NVR was then created using SolidWorks software. Five different solid 3D nasal valve models were created with nasolabial angles of 85˚ in Model 1, 90˚ in Model 2, 95˚ in Model 3, 100˚ in Model 4, and 105˚ in Model 5. To simulate breathing during rest and exercise using the CFD method, the unilateral nasal airflow rates were set at 150 ml/s and 500 ml/s, respectively. The CFD method was then used to calculate each model’s airflow properties. Finally, the volumes of the models, pressure at the NV outlet, and airflow velocity were evaluated and calculated to investigate each model’s NV airflow characteristics.
Results: Our study found a significant correlation between the nasolabial angle (NLA) and NVR volume (r=-0.998, p=0.000), flow rate and velocity (r=0.984, p=0.000), velocity and maximum pressure (r=0.920, p=0.000), velocity and minimum pressure (r=-0.969, p=0.000), flow rate and maximum pressure (r=0.974, p=0.000), and flow rate and minimum pressure (r=-0.950, p=0.000). There was no correlation between NLA increase and nasal airflow velocity. We determined that the highest pressure and lowest airflow velocity values were in the upper angle region and that the lowest pressure and highest airflow velocity values were at the bottom of the NVR in all models.
Conclusion: Using the CFD method, we found a decrease in NVR volume and an increase in airflow velocity with an increase in NLA. In addition, we found that the pressure values in the NVR did not change significantly with the increase in NLA.
PENERAPAN MODEL BLENDED LEARNING PADA MATA PELAJARAN FIKIH KELAS IV DI ERA NEW NORMAL
Authors: Alvin Nadiroh Robiatin 
Published: April 2023

Penelitian ini bertujuan untuk mengetahui perencanaan dan penerapan dalam menggunakan model blended learning pada mata pelajaran Fikih di era new normal. Metode penelitian yaitu metode deskriptif kualitatif dengan bentuk studi kasus. Kemudian untuk teknik pengumpulan data menggunakan wawancara, observasi, dokumentasi.Hasil dari penelitian ini yaitu: 1) Perencanaan model blended learning dilakukan dengan sitematis dari merencanakan waktu, lokasi, materi, metode, media, langkah-langkah pembelajaran, dan pembuatan RPP (Rencana Pelaksanaan Pembelajaran); 2) Penerapan model blended learning di MI Masyhariyah Kebontemu dapat peneliti simpulkan berlangsug dengan baik.
Epidemiological profile of pesticide poisoning cases in the State of Sergipe, Brazil: a retrospective analysis from 2007 to 2021
Authors: Luz Rafael Andersen Alves da Cruz , Oliveira Ana Beatriz Seixas , Garcia Vitor de Carvalho , Rafael Larissa Monteiro , Santos José Ronaldo dos , Lins Lívia Cristina Rodrigues Ferreira 
Published: April 2023

We aimed to characterize the epidemiological profile of reported cases of pesticide poisoning in the state of Sergipe between 2007 and 2021. Secondary data were obtained from the National Database of Notifiable Diseases Information System (SINAN) and National Toxicological Information System (SINITOX), through the Department of Informatics of the Unified Health System (DATASUS) and analysis performed using the free tool Google Sheets. During the studied period, 960 cases of exogenous pesticide poisoning were registered in the state. The municipality of Aracaju had the highest percentage of the number of cases. The incidence prevailed in females, in the 20-39 age group, in the brown race and among those with incomplete primary education. The most used toxic agent was rodenticide, suicide attempt predominated as a circumstance of use. Most cases resulted from a single acute exposure, confirmed by the clinical-epidemiological method, and evolved to a cure without sequelae. This study traced the epidemiological profile of the State of Sergipe with regard to the intoxication of the population and, in addition, brought little explored data and information that directly impacts policies aimed at reducing morbidity and mortality resulting from the use of pesticides.
Orthogonal analysis of variants in APOE gene using in-silico approaches reveals novel disrupting variants
Authors: Li Chang , Hou Ian , Ma Mingjia , Wang Grace , Bai Yongsheng , Liu Xiaoming 
Published: April 2023

Introduction: Alzheimer’s disease (AD) is one of the most prominent medical conditions in the world. Understanding the genetic component of the disease can greatly advance our knowledge regarding its progression, treatment and prognosis. Single amino-acid variants (SAVs) in the APOE gene have been widely investigated as a risk factor for AD Studies, including genome-wide association studies, meta-analysis based studies, and in-vivo animal studies, were carried out to investigate the functional importance and pathogenesis potential of APOE SAVs. However, given the high cost of such large-scale or experimental studies, there are only a handful of variants being reported that have definite explanations. The recent development of in-silico analytical approaches, especially large-scale deep learning models, has opened new opportunities for us to probe the structural and functional importance of APOE variants extensively.Method: In this study, we are taking an ensemble approach that simultaneously uses large-scale protein sequence-based models, including Evolutionary Scale Model and AlphaFold, together with a few in-silico functional prediction web services to investigate the known and possibly disease-causing SAVs in APOE and evaluate their likelihood of being functional and structurally disruptive.Results: As a result, using an ensemble approach with little to no prior field-specific knowledge, we reported 5 SAVs in APOE gene to be potentially disruptive, one of which (C112R) was classificed by previous studies as a key risk factor for AD.Discussion: Our study provided a novel framework to analyze and prioritize the functional and structural importance of SAVs for future experimental and functional validation.
Clinical values of metagenomic next-generation sequencing in patients with severe pneumonia: a systematic review and meta-analysis
Authors: Lv Minjie , Zhu Changjun , Zhu Chenghua , Yao Jing , Xie Lixu , Zhang Changwen , Huang Jianling , Du Xingran , Feng Ganzhu 
Published: April 2023

BackgroundClinical values of metagenomic next-generation sequencing (mNGS) in patients with severe pneumonia remain controversial. Therefore, we conduct this meta-analysis to evaluate the diagnostic performance of mNGS for pathogen detection and its role in the prognosis of severe pneumonia.MethodsWe systematically searched the literature published in PubMed, Embase, Cochrane Library, Web of Science, Clinical Trials.gov, CNKI, Wanfang Data, and CBM from the inception to the 28th September 2022. Relevant trials comparing mNGS with conventional methods applied to patients with severe pneumonia were included. The primary outcomes of this study were the pathogen-positive rate, the 28-day mortality, and the 90-day mortality; secondary outcomes included the duration of mechanical ventilation, the length of hospital stay, and the length of stay in the ICU.ResultsTotally, 24 publications with 3220 patients met the inclusion criteria and were enrolled in this study. Compared with conventional methods (45.78%, 705/1540), mNGS (80.48%, 1233/1532) significantly increased the positive rate of pathogen detection [OR = 6.81, 95% CI (4.59, 10.11, P &lt; 0.001]. The pooled 28-day and 90-day mortality in mNGS group were 15.08% (38/252) and 22.36% (36/161), respectively, which were significantly lower than those in conventional methods group 33.05% (117/354) [OR = 0.35, 95% CI (0.23, 0.55), P &lt; 0.001, I2 = 0%] and 43.43%(109/251) [OR = 0.34, 95% CI (0.21, 0.54), P &lt; 0.001]. Meanwhile, adjusted treatment based on the results of mNGS shortened the length of hospital stay [MD = -2.76, 95% CI (− 3.56, − 1.96), P &lt; 0.001] and the length of stay in ICU [MD = -4.11, 95% CI (− 5.35, − 2.87), P &lt; 0.001].ConclusionThe pathogen detection positive rate of mNGS was much higher than that of conventional methods. Adjusted treatment based on mNGS results can reduce the 28-day and 90-day mortality of patients with severe pneumonia, and shorten the length of hospital and ICU stay. Therefore, mNGS advised to be applied to severe pneumonia patients as early as possible in addition to conventional methods to improve the prognosis and reduce the length of hospital stay.