bluuebunny/crossref_metadata_2025_split huggingface dataset:
Patterns of aeroallergen sensitization in asthma patients identified by latent class analysis: A cross‐sectional study in China
Authors: Zhang Jiale , Luo Wenting , Li Guoping , Ren Huali , Su Jie , Sun Jianxin , Zhong Ruifen , Wang Siqin , Li Zhen'an , Zhao Yan , Ke Huashou , Chen Ting , Xv Chun , Chang Zhenglin , Wu Liting , Zheng Xianhui , Xv Miaoyuan , Ye Qingyuan , Hao Chuangli , Sun Baoqing 
Published: July 2023

AbstractBackgroundThis cross‐sectional study aimed to identify latent sensitization profiles of asthma patients in mainland China, unveiling the association between regional differences and sensitization patterns.Methods1056 asthma participants from 10 medical centers divided into eastern and western cohorts were clustered into four individual sensitization patterns, respectively, by using an unsupervised statistical modeling method, latent class analysis (LCA), based on the levels of 12 aeroallergens specific IgE reactivities. Moreover, differences in clinical characteristics and environmental exposures were compared in different sensitization patterns.ResultsFour distinct sensitization patterns in the two cohorts were defined as follows, respectively. Eastern cohort: Class 1: “High weed pollen and house dust mites (HDMs) sensitization” (8.87%), Class 2: “HDMs dominated sensitization” (38.38%), Class 3: “High HDMs and animal dander sensitization” (6.95%), Class 4: “Low/no aeroallergen sensitization” (45.80%). Western cohort: Class 1: “High weed pollen sensitization” (26.14%), Class 2: “High multi‐pollen sensitization” (15.02%), Class 3: “HDMs‐dominated sensitization” (10.33%), Class 4: “Low/no aeroallergen sensitization” (48.51%). Of note, the significant statistical difference in age, asthma control test score (ACT) and comorbidities were observed within or between different sensitization patterns. Exposure factors in different sensitization patterns were pointed out.ConclusionsAsthmatic patients with distinct sensitization patterns were clustered and identified through the LCA method, disclosing the relationship between sensitization profiles of multiple aeroallergens and geographical differences, providing novel insights and potential strategies for atopic disease monitoring, management and prevention in clinical practice.
Fine‐grained assured insertion and deletion scheme based on onion encryption in cloud storage
Authors: Tian Junfeng , Tian Naxi 
Published: July 2023

SummaryWith the current explosion of data volume and the rapid development of cloud computing, cloud storage is one of the most important services of cloud computing. It greatly reduces the cost of users and improves the convenience of use, but the separation of data control and ownership has led to a series of security problems. This article proposes a fine‐grained assured deletion scheme based on onion encryption (ADOE) to ensure the security of user data and achieve assured deletion of data. In the past, the solution was limited by the credibility of the third party, and due to the limitation of the administrator's computing power, there would be a window period for processing high concurrency. In this article, the third party is abandoned, and most of the work is handed over to the CSP. Through multilayer encryption of data and role‐based access control, flexible and fine‐grained access and deletion are realized. At the same time, with this scheme, Merkle hash tree (MHT) is improved, and a new data verification structure Merkle index hash tree (MIHT) is designed to quickly retrieve data blocks and provide deletion proof. Finally, through experimental comparison and theoretical demonstration, it is proved that ADOE is a safe, efficient, and usable solution.
6‐Endo‐dig versus 5‐exo‐dig: Exploring Radical Cyclization Preference with First‐, Second‐, and Third‐row Linkers using High‐level Quantum Chemical Methods
Authors: Baroudi Abdulkader , Jaradat Khaled , Karton Amir 
Published: July 2023

AbstractAs an expansion upon Baldwin rules, the cyclization reactions of hex‐5‐yn‐1‐yl radical systems with different first‐, second‐, and third‐row linkers are explored at the CCSD(T) level via means of the SMD(benzene)‐G4(MP2) thermochemical protocol. Unlike C, O, and N linkers, systems with B, Si, P, S, Ge, As, and Se linkers are shown to favor 6‐endo‐dig cyclization. This offers fundamental insights into the rational synthetic design of cyclic compounds. A thorough analysis of stereoelectronic effects, cyclization barriers, and intrinsic barriers illustrates that structural changes alter the cyclization preference by mainly impacting 5‐exo‐dig reaction barriers. Based on the high‐level computational modeling, we proceed to develop a new tool for cyclization preference prediction from the correlation between cyclization barriers and radical structural parameters (e. g., linker bond length and bond angle). A strong correlation is found between the radical attack trajectory angle and the reaction barrier heights, i. e., cyclization preference. Finally, the influence of stereoelectronic effects on the two radical cyclization pathways is further investigated in stereoisomers of hypervalent silicon system, which provides novel insight into cyclization control.
NiFe‐Coordination Polymers‐Derived Layered Double Hydroxides as Bifunctional Materials: Effect of the Ni : Fe Ratio on the Electrochemical Performance
Authors: Kumar Trivender , Devi Bandhana , Halder Aditi , Koner Rik Rani 
Published: July 2023

AbstractThe development of an efficient and cost‐effective material is highly desirable for electrochemical devices such as electrolyzers and supercapacitors. Especially, pseudomorphic transformations of metal‐organic frameworks (MOFs)/coordination polymers (CPs) into layered double hydroxides (LDHs) materials endow well‐defined porosities, high surface area, exchangeable interlayer anions and easily adjustable electronic structure that are truly required for oxygen evolution reaction (OER) and high‐performance supercapacitor applications. Herein, we have prepared NiFe‐LDHs of various Ni/Fe ratios via a facile room‐temperature alkaline hydrolysis of NiFe‐CPs precursors. Electrochemical studies reveal that the catalyst having high amount of Fe (Ni1.2Fe1‐LDH) showed the better OER activity with a low Tafel slope (65 mV dec−1) in 1 M KOH. On the other hand, the catalyst containing higher amount of Ni with better layered structure (Ni11.7Fe1‐LDH) showed high performance for supercapacitor (702 F g−1 at 0.25 A g−1) in 3 M KOH. Moreover, a solid‐state asymmetric supercapacitor device Ni11.7Fe1‐LDH/AC was fabricated which exhibited a specific capacitance of 18 F g−1 at a current density of 1 A g−1. The device displayed high cycling stability with 88% of capacitance retention after 7000 cycles. The experimental findings in this work will help in the futuristic development of NiFe‐LDH based electrocatalysts for the enhanced electrochemical performances.
The more the better? Service transition for shaping sustainable development in manufacturing firms and the role of top management team attributes
Authors: Huang Hai , Hao Shengbin , Chen Yu 
Published: July 2023

AbstractAn increasing number of manufacturing firms are actively embracing service transition in pursuit of sustainable competitive advantage. However, the relationship between service transition and sustainability performance (SP) remains unclear. Drawing on resource‐based theory and resource orchestration theory, this study investigates the impact of service transition (i.e., product‐related and product‐unrelated service transition) on SP and examines the moderating role of the top management team (TMT) attributes (i.e., stability and faultlines). We conduct OLS and 2SLS analyses using a unique longitudinal dataset from 522 listed Chinese manufacturing firms. Empirical evidence indicates that the two dimensions of service transition have distinct effects on SP. Product‐related service transition positively impacts SP, whereas product‐unrelated service transition shows an inverted U‐shaped relationship with SP. In addition, TMT stability strengthens the impact of product‐related service transition on SP, whereas TMT faultlines flatten the inverted U‐shaped relationship between product‐unrelated service transition and SP. This study addresses the research inconsistency concerning the implications of service transition on SP by elucidating the heterogeneous effects of different types of service transition on SP and the boundary role of TMT attributes. These findings also help firms revisit their service strategies and their TMT membership structure to enhance sustainability practices.
A 23–29.5 GHz three‐stage mm‐wave GaN power amplifier using arbitrary two‐port complex‐impedance matching method
Authors: Zhao Zi‐Ming , Zhu Xiao‐Wei , Xia Jing , Liu Rui‐Jia , Dong Qin , Chen Peng , Zhang Lei , Jiang Xin , Yu Chao , Hong Wei 
Published: July 2023

SummaryThis paper presents a broadband monolithic millimeter‐wave integrated circuit GaN power amplifier (PA) with arbitrary two‐port complex‐impedance matching method. The proposed matching topology has been applied to interstage matching network design by modifying traditional coupling matrix and synthesizing a desired network. The optimum load traction technique is introduced to provide some more suitable Zopts. After continuous‐wave test, the three‐stage MMIC PA achieves a peak PAE of 39.1% with a 34.9 dBm output power from 23 to 29.5 GHz and the measured S21 is 32.5 dB with a ±2.5 dB gain variation. When driven by a 400 MHz OFDM modulation signal with a PAPR of 8.5 dB, the measured ACPR is improved to −40.6/−40.7 dBc with DPD. In this case, the PA achieves an average PAE of 11.7% and a 26.7 dBm average output power.
A digitally controlled switched‐ring oscillator‐based time domain multiply‐and‐accumulate core for machine learning
Authors: Du Kevin , Abdelaziz Ahmed , Musah Tawfiq 
Published: July 2023

AbstractThis article presents a time domain multiply‐and‐accumulate (MAC) engine used for convolutional neural networks. Time domain is chosen for efficiency as it allows for compact representation of multi‐bit inputs on a single wire. This reduces gate count and switching capacitance (Cdyn) compared to traditional all‐digital implementation. The inputs are encoded by selecting a pulse of varying width depending on input code. The multiplication operation and accumulation is implemented using a digitally controlled switched‐ring oscillator time‐to‐digital converter functioning as a time accumulator. The digital control allows for accumulation and quantization of two signals simultaneously, halving the required time to quantize a certain value. The proposed MAC is designed in a 28 nm CMOS process and can achieve a simulated power efficiency of 0.32 pJ/b, which is 1.8
better than what can be achieved by a single input gated ring oscillator (GRO) design.
Energy‐efficient data transmissions in heterogeneous ultra‐dense networks using a hybrid metaheuristic optimization
Authors: V Varsha. , Prakash S. P. Shiva , Krinkin Kirill 
Published: July 2023

SummaryThe heterogeneous ultra‐dense network (UDN) is a complex network environment where the small cells (SCs) are densely populated to acquire data transmission. The UDN is mainly adopted to deal with the explosive growth of mobile data and its consequential energy consumption issues. The UDN consists of mobile users, restricting the SCs from offering seamless services as the movement may disrupt the transmissions. To provide an effective solution, this paper introduces an energy‐efficient framework that enables effective data transmissions irrespective of the users' mobility. The proposed model considers the clustered SC deployment where the four‐tiered architecture is adopted. The architecture includes a macro base station (BS), microcells, picocells, and femtocells. The SCs are responsible for transferring the data received from the mobile users to the macro BS. The proposed model introduces the hybrid algorithm called the firefly oriented multiverse optimization (FF‐MVO) algorithm to identify the most optimal path for data transmission. This algorithm works iteratively to identify the optimal path to reach the macro BS for each transmission from the user. The proposed model is simulated in the network simulator 3 (NS3) platform, and the results are evaluated with the existing models. The outcomes proved that the proposed algorithm is more optimal than the other models in finding the optimal path to result in energy‐efficient transmissions. The proposed method achieved an average energy consumption of 0.24 J, an average energy efficiency of 10.965 bits/s/J and an average network throughput of 33.907 Gbps.
Identifying important individual‐ and country‐level predictors of conspiracy theorizing: A machine learning analysis
Authors: Douglas Karen M. , Sutton Robbie M. , Van Lissa Caspar J. , Stroebe Wolfgang , Kreienkamp Jannis , Agostini Maximilian , Bélanger Jocelyn J. , Gützkow Ben , Abakoumkin Georgios , Khaiyom Jamilah Hanum Abdul , Ahmedi Vjollca , Akkas Handan , Almenara Carlos A. , Atta Mohsin , Bagci Sabahat Cigdem , Basel Sima , Berisha Kida Edona , Bernardo Allan B. I. , Buttrick Nicholas R. , Chobthamkit Phatthanakit , Choi Hoon‐Seok , Cristea Mioara , Csaba Sára , Damnjanovic Kaja , Danyliuk Ivan , Dash Arobindu , Di Santo Daniela , Enea Violeta , Faller Daiane Gracieli , Fitzsimons Gavan , Gheorghiu Alexandra , Gómez Ángel , Hamaidia Ali , Han Qing , Helmy Mai , Hudiyana Joevarian , Jeronimus Bertus F. , Yu Jiang Ding‐ , Jovanović Veljko , Kamenov Željka , Kende Anna , Keng Shian‐Ling , Kieu Tra Thi Thanh , Koc Yasin , Kovyazina Kamila , Kozytska Inna , Krause Joshua , Kruglanski Arie W. , Kurapov Anton , Kutlaca Maja , Lantos Nóra Anna , Lemay Edward P. , Lesmana Cokorda Bagus Jaya , Louis Winnifred R. , Lueders Adrian , Malik Najma Iqbal , Martinez Anton , McCabe Kira O. , Mehulić Jasmina , Milla Mirra Noor , Mohammed Idris , Molinario Erica , Moyano Manuel , Muhammad Hayat , Mula Silvana , Muluk Hamdi , Myroniuk Solomiia , Najafi Reza , Nisa Claudia F. , Nyúl Boglárka , O'Keefe Paul A. , Olivas Osuna Jose Javier , Osin Evgeny N. , Park Joonha , Pica Gennaro , Pierro Antonio , Rees Jonas , Reitsema Anne Margit , Resta Elena , Rullo Marika , Ryan Michelle K. , Samekin Adil , Santtila Pekka , Sasin Edyta , Schumpe Birga M. , Selim Heyla A. , Stanton Michael Vicente , Sultana Samiah , Tseliou Eleftheria , Utsugi Akira , van Breen Jolien Anne , Van Veen Kees , vanDellen Michelle R. , Vázquez Alexandra , Wollast Robin , Yeung Victoria Wai‐Lan , Zand Somayeh , Žeželj Iris L. , Zheng Bang , Zick Andreas , Zúñiga Claudia , Leander N. Pontus 
Published: July 2023

AbstractPsychological research on the predictors of conspiracy theorizing—explaining important social and political events or circumstances as secret plots by malevolent groups—has flourished in recent years. However, research has typically examined only a small number of predictors in one, or a small number of, national contexts. Such approaches make it difficult to examine the relative importance of predictors, and risk overlooking some potentially relevant variables altogether. To overcome this limitation, the present study used machine learning to rank‐order the importance of 115 individual‐ and country‐level variables in predicting conspiracy theorizing. Data were collected from 56,072 respondents across 28 countries during the early weeks of the COVID‐19 pandemic. Echoing previous findings, important predictors at the individual level included societal discontent, paranoia, and personal struggle. Contrary to prior research, important country‐level predictors included indicators of political stability and effective government COVID response, which suggests that conspiracy theorizing may thrive in relatively well‐functioning democracies.
Downregulation of circular RNA hsa_circ_0087856 sensitizes bladder cancer cells to cisplatin through targeting miR‐1184/CITED2 signaling
Authors: Ju Min , Wu Weiwei , Qu Jingkun , Sun Yang , Li Jun 
Published: July 2023

AbstractCircRNAs are considered as one of the potential therapeutic targets of multiple cancers. According to accumulating evidence, circRNA regulates cancer progression by acting as a miRNA sponge. In the current work, our data discovered that hsa_circ_0087856 and CITED2 expression was increased, while miR‐1184 expression was decreased in BC cell lines and tissues. Hsa_circ_0087856 expression negatively correlated with miR‐1184, whereas positively correlated with CITED2. Hsa_circ_0087856 silencing suppressed BC tumor growth, and contributed to the inhibition of cisplatin to tumor growth. In cellular experiments, hsa_circ_0087856 increasing promoted BC cells proliferation, migration and invasion, and inhibited the cells apoptosis. Hsa_circ_0087856 increasing partly reversed the inhibition of cisplatin to BC cell proliferation and the promotion to cell apoptosis. Oppositely, hsa_circ_0087856 silencing could increase the sensitivity of BC cells to cisplatin. Hsa_circ_0087856 promoted CITED2 expression through binding with miR‐1184 and inhibiting its expression. CITED2 increasing partly reversed the promotion of hsa_circ_0087856 silencing to cisplatin‐induced BC cells apoptosis promotion and proliferation suppression. Overall, our results revealed the role of hsa_circ_0087856 that downregulation its expression could enhance the BC cells sensitivity to cisplatin by facilitating CITED expression via sponging miR‐1184. Moreover, our research provided a potential therapeutic target for BC.
Detoxification activity of bioactive food compounds against ethanol‐induced injuries and hangover symptoms: A review
Authors: Moslemi Masoumeh , Jannat Behrooz , Mahmoudzadeh Maryam , Ghasemlou Mehran , Abedi Abdol‐Samad 
Published: July 2023

AbstractAlcohol drinking is a popular activity among adolescents in many countries, largely due to its pleasant, relaxing effects. As a major concern, ethanol consumption put the drinkers at risk of nutrients' deficiency due to the disordered eating, anorexia, and malabsorption of nutrients. Moreover, alcohol drinking may lead to the development of hangover symptoms including diarrhea, thirsty, fatigue, and oxidative stress. A broad range of functional food components with antioxidant and/or anti‐inflammatory properties including pectin, aloe vera polysaccharides, chito‐oligosaccharides, and other herbal components have been explored due to their detoxification effects against ethanol. The underlying anti‐hangover mechanisms include reducing the intestinal absorption of ethanol or its metabolites, increasing the activity of ethanol metabolizing enzymes, development of fatty acid β‐oxidation in mitochondria, inhibition of inflammatory response, blocking the target receptors of ethanol in the body, and possession of antioxidant activity under the oxidative stress developed by ethanol consumption. Therefore, the development of bioactive food‐based therapeutic formula can assist clinicians and also drinkers in the alleviation of alcohol side effects.
Understanding depression in older Indians using diathesis‐stress framework: The role of neighborhood safety and physical and functional health
Authors: Muhammad Thalil , Thakkar Shriya , Balachandran Arun 
Published: July 2023

AbstractObjectivesThe interplay between an individual's vulnerability and related stressors, effectively termed as diathesis, is an important contributor towards depressive symptoms. Utilizing the diathesis‐stress model, the present study examines the role of perceived neighborhood safety along with specific indicators of health such as activities of daily living (ADL) and self‐rated health (SRH), and their associations with depressive symptoms among older Indian adults.Study designA cross‐sectional study has been conducted.MethodsData were drawn from the Longitudinal Aging Study in India wave 1 that was collected during 2017–18. The present study is conducted on respondents aged 60 years and above and the sample included 31,464 older adults. Depressive symptoms were assessed using the Short Form Composite International Diagnostic Interview (CIDI‐SF).ResultsIn this study, approximately 14.3% of the older participants reported perceiving their neighborhood as unsafe. A total of 23.77% and 24.21% of older adults reported at least one difficulty in ADL and poor SRH, respectively. Older adults who had perceived their neighborhood as unsafe had higher odds of reporting depressive symptoms [AOR: 1.758, CI: 1.497–2.066] than those with the perception of a safe neighborhood. Those with a perceived unsafe neighborhood and low ADL functioning had approximately 3.3 times higher odds of reporting depressive symptoms [AOR: 3.298, CI: 2.553–4.261] than those with a safe perceived neighborhood and high ADL functioning. Further, older adults with unsafe perceived neighborhood, low ADL functioning and poor SRH had much greater odds of reporting depressive symptoms [AOR: 7.725, CI: 5.443–10.960] than those with a safe perceived neighborhood, high ADL functioning and good SRH. Additionally, depressive symptoms were pronounced among older women and those who resided in rural areas with unsafe perceived neighborhood, low ADL functioning and poor SRH than their male peers.ConclusionsThe findings suggest that older women and rural‐dwelling older adults are more prone to have higher prevalence of depressive symptoms than their male and urban‐dwelling peers, especially when they have an unsafe neighborhood and poor functional and physical health, and thus, they should be given focused care and attention by healthcare practitioners.
Change in patient‐centered outcomes of psychological well‐being, sleep, and suicidality following treatment with intravenous ketamine for late‐life treatment‐resistant depression
Authors: Vanderschelden Benjamin , Gebara Marie Anne , Oughli Hanadi Ajam , Butters Meryl A. , Brown Patrick J. , Farber Nuri B. , Flint Alastair J. , Karp Jordan F. , Lavretsky Helen , Mulsant Benoit H. , Reynolds Charles F. , Roose Steven P. , Lenze Eric J. 
Published: July 2023

AbstractObjectiveTo examine whether psychological well‐being, sleep, and suicidality improved with treatment with intravenous (IV) ketamine for late‐life treatment‐resistant depression (TRD).MethodsThis is an analysis of secondary outcomes in an open‐label late‐life TRD study examining the safety, tolerability, and feasibility of IV ketamine infusions. In the acute phase, participants (N = 25) aged 60 years or older received twice‐a‐week IV ketamine for 4 weeks. Then, participants with Montgomery‐Asberg Depression Rating Scale (MADRS) total score <10 or ≥ 30% reduction from baseline proceeded to the continuation phase, an additional four weeks of once‐a‐week IV ketamine. The secondary outcomes analyzed here are based on the National Institute of Health Toolbox Psychological Well‐Being subscales for Positive Affect and General Life Satisfaction, the Pittsburgh Sleep Quality Index, and the Scale for Suicidal Ideation.ResultsPsychological well‐being, sleep, and suicidality improved during the acute phase and those improvements were sustained during the continuation phase. Greater improvements in measures of psychological well‐being and sleep were seen in participants who had greater improvements in MADRS scores and moved onto the continuation phase. All but one of the few participants with high suicidality at baseline improved; there were no cases of treatment‐emergent suicidality.ConclusionsPsychological well‐being, sleep, and suicidality improved in participants with late‐life TRD who received IV ketamine for 8 weeks. A future larger and longer controlled trial is needed to confirm and extend these findings.RegistrationClinicalTrials.gov identifier: NCT04504175.