bluuebunny/crossref_metadata_2025_split huggingface dataset:
Expert Consensus for the Use of Outpatient Rehabilitation Visits After Total Knee Arthroplasty: A Delphi Study
Authors: Graber Jeremy , Churchill Laura , Struessel Tamara , O’Malley Shane , Bade Michael , Stevens-Lapsley Jennifer 
Published: July 2023

OBJECTIVE: There is no consensus for how to use rehabilitation visits after total knee arthroplasty (TKA). We sought to develop expert recommendations for outpatient rehabilitation visit usage after TKA. DESIGN: Delphi study. METHODS: First, we developed a broad list of preliminary visit usage recommendations, which were specific to patients’ recovery status (ie, slow, typical, or fast recovery) and time since surgery. We then invited 49 TKA experts to participate on a Delphi panel. During round 1, we surveyed panelists regarding their level of agreement with each preliminary recommendation. We conducted additional Delphi rounds as needed to build consensus, which we defined using the RAND/UCLA method. We updated the survey each round based on panelist feedback and responses from the previous round. RESULTS: Thirty panelists agreed to participate, and 29 panelists completed 2 Delphi rounds. The panel reached consensus on recommendations related to visit frequency, visit timing, and the use of telerehabilitation. The panel recommended that outpatient rehabilitation should begin within 1 week after surgery at a frequency of 2 times per week for the first postoperative month regardless of recovery status. The panel recommended different visit frequencies depending on the patient’s recovery status for postoperative months 2 to 3. The panel agreed that telerehabilitation can be recommended for most patients after TKA, but not for patients recovering slowly. CONCLUSION: We used the Delphi process to develop expert recommendations for the use of outpatient rehabilitation visits after TKA. We envision these recommendations could help patients decide how to use visits based on their own preferences. J Orthop Sports Phys Ther 2023;53(9):566-574. Epub: 10 July 2023. doi:10.2519/jospt.2023.11840
Complications of Third Molar Extraction done by BDS Interns under Supervision in a Dental College in Central India
Authors: Mujeeb Biswas  , Rohit Punia  , Anam Khan  
Published: July 2023

INTRODUCTION: Third molar is the most commonly observed impacted tooth in the oral cavity, with a higher prevalence among mandibular teeth. AIM: To assess the Complications of Third Molar Extraction done by BDS Interns under Supervision in a Dental College in Central India. MATERIALS AND METHOD: This cross-sectional study was conducted over a period of three years. BDS interns between the years 2016-2018 posted in the department of oral surgery were observed while doing third molar extractions under supervision. All patients underwent standard surgical protocol. Routine follow-up was done after one week and suture was removed. Complications, if any were noted down by the faculty and appropriate management of the same was done by the OPD incharge. Patients not available for follow up were excluded from the analysis. Data was analyzed using SPSS version 23.0. and the student’s independent samples t-test was applied to find out associations between the complications. RESULTS: A total of 1368 patients were included and a total of 2369 third molars were extracted with a majority of the teeth being in the mandibular region (69.8%). Males (62.5%) formed a majority of the population. The most common intra-operative complication was Swelling/pain/ trismus (36.8%) followed by dry socket (14.9%). Whereas the most common intra-operative complication was soft tissue injury (1.9%) followed by bleeding at the extraction site (1.8%). Both soft tissue injury (p=0.02) and swelling/pain/trismus (p=0.03) were found to be significant. CONCLUSION: The low percentages of intra-operative and post-operative complications among interns indicate adherence to proper exodontia protocols.
Rhythm As Creative System In Houses Architecture Comparative Application Study Between Heritage And Contemporary Houses
Authors: M. Nasma Maan , S. Basma A. , Idrees Ebtisam Sameer 
Published: July 2023

Rhythm is considered one of the creative concepts in the recent architectural thought; it has emerged clearly as a mean of creating the highest levels of creativity in architecture, especially in contemporary architectural movements. The importance of rhythm has emerged, especially, when the architecture , its beginnings concentrated on the principle of the links with poetic structures. Many architectural studies deal with concept of rhythm in architecture with different ways various according to the trend of each study, this show the importance of studying the concept of rhythm in the architectural field in general. This study try to focus on the utilization of rhythm as creative system in architecture of heritage and contemporary house because its important in the generation of new architectural models. The paper discusses the importance of this concept and its utilization in the designs, in order to explore the particular problem which has been represented as (The absence of a specific imagination of methods and strategies for achieving rhythm).Thus the objectives of the paper has been formed by building theoretical framework consisting of five main items of detailed theoretical field which specifies rhythm as a concept ,firstly, then the application of the important heritage and contemporary houses in Mosul Architecture as a model, concluding utilization of rhythm as creative system in Heritage and Contemporary Houses in Mosul Architecture, finally, after discussing the results to submit the conclusions in the end. The conclusion is That suitable rhythm creativity in Mosul architecture is by unit and immerge the Mosul cultural elements as new tool in steps of design process of Heritage and Contemporary Houses in Mosul.
أثر المكان على السياحة
Authors: الخفاجي صبا جبار نعمة , الجميلي سعد خضير محمود 
Published: July 2023

Most communities seek, which possesses a cultural legacy to communicate with the past and to reach the best possible legislation to help them protect their cultural. Tourism as the economic development based on the data in light distinct places, including traditional and historical environments requiring activated and revived in my adopting the concept of transnational Revival Tourism. Through the survey data in environments where conventional and (historical - Sensationalism) theoretically and practically, it was drawn from a number of indicators truth spatial phenomenon and the phenomenon depends show and try on a number of variables and interventions including historical and philosophical interpretations of those facts, in addition to theoretical and policy orientations or local government. Those indicators were tested on four samples were Aleppo castle and its surroundings, and the old city of Aleppo and its surroundings, adopted by the state of research as a cultural one and intertwined with historical and archaeological values and traditional surroundings, to explore the values underlying facts percentage-active (frozen), which show depends on the ability and activate planned and designed urban and domestic policies on the understanding and use of historian , archeologist and sociologists. . The percentage values College Library 42% in the four samples relative values but they must be significant and have an impact in increasing the visibility and location in the event activated.
Logika Matematika Sebagai Alternatif Ilmu Mantiq Yang Diaplikasikan Untuk Takarub
Authors: Ananto Al Ninantari  Dimarzio , Syafitri Aidhella , Amalia  Rosa Oktaviani  , Agil Julian Nugroho  , Farhan Syarif  , Aditia Muhammad Noor  
Published: July 2023

This research examines whether mathematics, especially mathematical logic in thinking, can be a replacement way to the exert of mantiq in the concept of getting closer to Allah SWT. Mathematics, which is more accessible than Mantiq, was one of the considerations in writing this study. This study intends to provide benefits and open people's views that mathematics, which precipitates logic, can also be linear with religious knowledge, such as the science of mantiq. So it is aspiration that in the time ahead, by studying the logic of mathematics, humans can apply it to matters related to getting closer to Allah SWT. Library research is the research methodology applied.. This literature research was carried out in a systematic and highly structured manner so that the literature sources in this article that have been published in an approach which guarantees the most effective results as the most relevant literature sources. This article will be written in descriptive-analytical form so that the research results can be described in detail, accurately, and easily understood. The final result of this paper will be published so anyone could directly understand that mathematics is a systematic science and constructing logic can be carry out in line with religious scholarship, where mathematics used to understand the concept of the oneness of Allah SWT. Understanding systems in mathematical logic can also help us understand Islamic concepts such as monotheism, destiny, and the hereafter. The application of mathematical logic can also help someone to think logically and systematically about drawing closer to Allah SWT so that they can avoid going astray.
Efektivitas Pembelajaran CPS (Creative Problem Solving) terhadap Kemampuan Berpikir Tingkat Tinggi Siswa Madrasah Tsanawiyah Plus Nabawi Kedungadem Pada Mata Pelajaran Fiqih
Authors: Shofiyudin Ahmad , Fauziah Zumrotul , Iswati Yulya 
Published: July 2023

Latar belakang penelitian ini adalah rasa bosan siswa dalam pembelajaran Fiqih serta kemampuan peserta didik dalam pemecahan masalah (problem solving) yang tergolong masih rendah. Adapun kemampuan berpikir siswa dapat meningkat dengan adanya penggunaan suatu model pembelajaran. Variabel bebas (independent) dan terikat (dependent) dalam penelitian kuantitatif ini ialah model pembelajaran Creative Problem Solving dan Kemampuan Berpikir Tingkat Tinggi (HOTS). Penelitian kuantitatif ini bertujuan untuk mengetahui Efektif atau tidaknya model pembelajaran Creative Problem Solving (CBS) terhadap kemampuan berpikir tingkat tinggi (HOTS) siswa kelas VIII MTs Plus Nabawi Kedungadem.
Pendekatan kuantitatif pre-eksperimen pada penelitian ini menggunakan desain the one group pre-test post-test design. Yang menjadi sampel dalam penelitian ini ialah siswa kelas VIII MTs Plus Nabawi Kedungadem dengan junlah siswasebanyak 20. Pengukuran Kemampuan Berpikir Tingkat Tinggi Siswa (HOTS) siswa menggunakan Teknik pengumpulan data berupa pre test serta untuk mengukur efektivitas model pembelajaran Creative Problem Solving terhadap kemampuan berpikir tingkat tinggi (HOTS) siswa, peneliti menggunakan teknik pengumpulan data berupa prettets dan post test. Analisis data berupa uji validitas, uji reliabilitas, uji normalitas, uji linieritas, uji hipotesis yaitu Teknik analisis uji t sampel berpasangan.
Berdasarkan penelitian yang dilakukan, penelitian menunjukkan bahwa model pembelajaran Creative Problem Solving efektif terhadap kemampuan berpikir tingkat tinggi (HOTS) siswa kelas VIII, hasilnya diperoleh pada pengujian korelasi yaitu thitung > ttabel atau -7,350 > 2,093. Berdasarkan hal tersebut maka disimpulkan bahwa (Ha) diterima dan (Ho) ditolak.
EXPONENTIAL-SELF-ADAPTIVE RANDOM EARLY DETECTION SCHEME FOR QUEUE MANAGEMENT IN NEXT GENERATION ROUTERS
Authors: Surajo Yusuf , Suleiman Aminu Bashir , Yahaya Usman 
Published: July 2023

ensuring optimal performance in next-generation routers. Active Queue Management (AQM) scheme, has been advocated by the Internet research community for the next generation routers. Random Early Detection (RED) is the most well-known AQM scheme. However, RED lacks self-adaptation mechanism and it is susceptible to parametrization problem. Several variants of RED were developed, however all of them possess a static drop pattern; as such they are severely affected when a traffic load changes. To address the self-adaptation shortcoming of the RED and its variant schemes, Self-Adaptive Random Early Detection (SARED) scheme was developed. However, to avoid congestion, SARED aggressively drops packets once the queue length reached a certain maximum threshold limit, subsequently, this will increase the average queuing delay for networks with high traffic load conditions, therefore, to eliminate the aggressiveness of SARED in such situations, an Exponential version of SARED was proposed in this paper. Results of the simulation experiments carried out have indicated that in high traffic load situations, Exponential-SARED (ESARED) has significantly reduced average queuing delay by 4% and maximized average throughput by 3% compared to SARED and QERED.
Disfunción endotelial en la salud cardiometabólica
Authors: Mera Flores Ronny Richard , Toapanta Pullutasig Isaac , Chasing Vilela Eva María , Murillo Tapia Carolina , Murillo Tapia Catalina 
Published: July 2023

Introducción: las enfermedades cardiometabólicas son de las principales causas de muerte de personas en todo el mundo y disfunción endotelial interrumpe la permeabilidad de la barrera endotelial que forma parte de la respuesta inflamatoria en el desarrollo de estas. Como tal, la anulación de la activación e inflamación de las células endoteliales tiene relevancia clínica, promoviendo este grupo de enfermedades degenerativas. Objetivo: exponer las generalidades del endotelio y la asociación de su disfunción con algunas de las principales enfermedades cardiometabólicas abordadas en el primer nivel de atención. Metodología: revisión narrativa de la literatura que incluyó 52 artículos seleccionados en base a su disponibilidad abierta y ser publicados en inglés y español. Conclusiones: el endotelio, como célula activa en el proceso de inflamación – incluida la inflamación silente o de bajo grado – constituye una diana de profundo estudio por parte de los profesionales de la salud que trabajan con pacientes cardio metabólicos, el enfoque dirigido a esta y a sus productos por y antiinflamatorios, en un futuro no lejano, podría incrementar aún más en el contexto del tratamiento médico y la prevención cardiometabólica.
Prevalencia, factores de riesgo e impacto de la demencia en la República Dominicana
Authors: Acosta Daisy 
Published: July 2023

Introducción: La demencia es la primera causa de discapacidad en adultos mayores y la mayor contribuyente de dependencia, sobrecarga económica y estrés psicológico en el cuidador, sin embargo, aún no recibe la misma prioridad que otras enfermedades crónicas no trasmisibles.
Objetivo: Estimar la prevalencia, asociaciones de riesgo e impacto de la demencia en adultos de 65 años y más en una comunidad de bajos ingresos en Santo Domingo, República Dominicana.
Sujetos y métodos: Se realizó un estudio prospectivo longitudinal de una cohorte de 2011 adultos de 65 años y más, en los sectores de Villa Francisca, San Carlos, Zona Colonial, Mejoramiento Social y zonas aledañas, en dos fases: la primera, un estudio de corte transversal, puerta a puerta, durante el periodo 2003–2006 y la segunda, el seguimiento y evaluación de la cohorte, realizado entre el 2007 y el 2010, con una media de seguimiento de 5.1 años. El diagnóstico de demencia se realizó de acuerdo con los criterios del DSM IV y los criterios propuestos por el Grupo de Investigación 10/66. Se evaluaron los factores de riesgos vasculares y otras enfermedades crónicas según los criterios internacionalmente establecidos. Se utilizaron para evaluar el impacto de la demencia dos indicadores: necesidades de cuidados y morbilidad psicológica del cuidador.

Resultados: La prevalencia de síndrome demencial según los criterios del DSM IV es de 5.4 % y de 11.7 % según los criterios del 10/66 en la población de 65 años y más, asociándose en el estudio transversal a diversos factores de riesgo, en particular edad avanzada, antecedentes de trauma craneal, historia familiar de demencia y antecedentes de ictus. La demencia, en una proporción mayor que el ictus, la depresión y tener enfermedades físicas limitantes, constituyó el mayor contribuyente de necesitar cuidado en la población estudiada.
Conclusión: La prevalencia de la demencia en la República Dominicana es elevada. Se requiere brindar una mayor prioridad a enfermedades crónicas, como la demencia en especial, ya que está asociada a mayores necesidades de cuidados y por tanto a mayor discapacidad, generando esto una alta carga social económica y de salud.
Integrated multiple-microarray analysis and mendelian randomization to identify novel targets involved in diabetic nephropathy
Authors: Fan Chenyu , Gao Yuye , Sun Ying 
Published: July 2023

BackgroundDiabetic nephropathy (DN), which is the main cause of renal failure in end-stage renal disease, is becoming a common chronic renal disease worldwide. Mendelian randomization (MR) is a genetic tool that is widely used to minimize confounding and reverse causation when identifying the causal effects of complex traits. In this study, we conducted an integrated multiple microarray analysis and large-scale plasma proteome MR analysis to identify candidate biomarkers and evaluate the causal effects of prospective therapeutic targets in DN.MethodsFive DN gene expression datasets were selected from the Gene Expression Omnibus. The robust rank aggregation (RRA) method was used to integrate differentially expressed genes (DEGs) of glomerular samples between patients with DN and controls, followed by functional enrichment analysis. Protein quantitative trait loci were incorporated from seven different proteomic genome-wide association studies, and genetic association data on DN were obtained from FinnGen (3676 cases and 283,456 controls) for two-sample MR analysis. External validation and clinical correlation were also conducted.ResultsA total of 82 DEGs (53 upregulated and 29 downregulated) were identified through RRA integrated analysis. The enriched Gene Ontology annotations and Kyoto Encyclopedia of Genes and Genomes pathways of the DEGs were significantly enriched in neutrophil degranulation, neutrophil activation, proteoglycan binding, collagen binding, secretory granule lumen, gluconeogenesis, tricarboxylic acid cycle, and pentose phosphate pathways. MR analysis revealed that the genetically predicted levels of MHC class I polypeptide-related sequence B (MICB), granzyme A (GZMA), cathepsin S (CTSS), chloride intracellular channel protein 5, and ficolin-1 (FCN1) were causally associated with DN risk. Expression validation and clinical correlation analysis showed that MICB, GZMA, FCN1, and insulin-like growth factor 1 may participate in the development of DN, and carbonic anhydrase 2 and lipoprotein lipase may play protective roles in patients with DN.ConclusionOur integrated analysis identified novel biomarkers, including MICB and GZMA, which may help further understand the complicated mechanisms of DN and identify new target pathways for intervention.
Analysis of platelet and monocyte-to-lymphocyte ratio and diabetes mellitus with benign prostatic enlargement
Authors: Chen Guanheng , Feng Leiguang 
Published: July 2023

BackgroundThe etiology of benign prostatic hyperplasia (BPH) is still elusive. The aim of this study was to provide preventive and prognostic parameters associated with diabetes mellitus with benign prostatic enlargement (BPE).MethodsDiabetic patients were collected retrospectively from February 2021 to December 2022, including monocyte-to-lymphocyte ratio (MLR). Diabetic patients were divided into two groups by whether the prostate volume was greater than or equal to 30 ml, which were diabetes mellitus without BPE (DM) and diabetes mellitus with BPE (DM+BPE). The baseline characteristics were compared, the risk and protective factors associated with DM+BPE were determined using univariate and multivariate logistic regression, and the parameters associated with prostate volume were determined using correlation analysis.ResultsOf the 671 patients collected, age and prostate volume were significantly higher in the DM+BPE than in the DM; MLR was higher in the DM+BPE than in the DM; and platelet was significantly lower in the DM+BPE than in the DM. Univariate logistic regression showed that age was a risk factor, while protective factors for DM+BPE were lymphocytes and platelet. Multifactorial logistic regression showed that age was a risk factor, while platelet was the protective factor for DM+BPE. In the total overall (n=671), prostate volume was positively correlated with age. Prostate volume was negatively correlated with lymphocytes and platelet. In DM+BPE (n=142), prostate volume was positively correlated with age and MLR.ConclusionPlatelet was a protective factor for DM+BPE and was negatively correlated with prostate volume, whereas MLR was positively correlated with prostate volume in DM+BPE.
Transcriptome analysis reveals reduced immunity and metabolic level under cold stress in Mauremys mutica
Authors: OuYang Jiahui , Gao Yangchun , Wei Yufeng , Huang Huangping , Ge Yan , Zhao Jun , Gong Shiping 
Published: July 2023

The yellow pond turtle (Mauremys mutica) is widely cultured for food, medicine and for keeping as pets in China. The high risk of disease outbreaks and mortality caused by sudden sharp temperature drop events has significant negative effects on the aquaculture industry of M. mutica. However, the mechanism underlying the damage caused by cold stress is still unclear. To fill this gap, we performed transcriptome sequencing of M. mutica samples collected at three sampling time points (3h, 24h and 48h) during cold treatment, and at a recovery time point (96 h after the end of cold stress). The results showed that immunity and metabolism-related pathways (neuroactive ligand-receptor interactions, cytokine-cytokine receptor interactions and NOD-like receptor signaling pathways) were significantly enriched at both 24h and 48h. The expression of immunity and metabolism-related genes (BS2A1, PIWIL2 and Fads1) significantly decreased at all-time points compared to the control group. These results suggested that impaired immunity and depressed metabolism under cold stress may be the main cause of the massive cold-stress mortality of M. mutica. This study provides novel insights into the molecular mechanisms underlying mass disease and mortality caused by sudden sharp temperature drop events in M. mutica.