bluuebunny/crossref_metadata_2025_split huggingface dataset:
ZBTB7A regulates MDD-specific chromatin signatures and astrocyte-mediated stress vulnerability in orbitofrontal cortex
Authors: Fulton Sasha L. , Bendl Jaroslav , Gameiro-Ros Isabel , Fullard John F. , Al-Kachak Amni , Lepack Ashley E. , Stewart Andrew F. , Singh Sumnima , Poller Wolfram C. , Bastle Ryan M. , Hauberg Mads E. , Fakira Amanda K. , Chen Min , Durand-de Cuttoli Romain , Cathomas Flurin , Ramakrishnan Aarthi , Gleason Kelly , Shen Li , Tamminga Carol A. , Milosevic Ana , Russo Scott J. , Swirski Filip , Blitzer Robert D. , Slesinger Paul A. , Roussos Panos , Maze Ian 
Published: May 2023

SummaryHyperexcitability in the orbitofrontal cortex (OFC) is a key clinical feature of anhedonic domains of Major Depressive Disorder (MDD). However, the cellular and molecular substrates underlying this dysfunction remain unknown. Here, cell-population-specific chromatin accessibility profiling in human OFC unexpectedly mapped genetic risk for MDD exclusively to non-neuronal cells, and transcriptomic analyses revealed significant glial dysregulation in this region. Characterization of MDD-specific cis-regulatory elements identified ZBTB7A – a transcriptional regulator of astrocyte reactivity – as an important mediator of MDD-specific chromatin accessibility and gene expression. Genetic manipulations in mouse OFC demonstrated that astrocytic Zbtb7a is both necessary and sufficient to promote behavioral deficits, cell-type-specific transcriptional and chromatin profiles, and OFC neuronal hyperexcitability induced by chronic stress – a major risk factor for MDD. These data thus highlight a critical role for OFC astrocytes in stress vulnerability and pinpoint ZBTB7A as a key dysregulated factor in MDD that mediates maladaptive astrocytic functions driving OFC hyperexcitability.
Anatomy of interactions among risk factors influencing implementation of building information modeling (BIM): a system dynamics approach
Authors: Zarghami Seyed Ashkan 
Published: May 2023

PurposeThe overarching objective of this paper is to examine the cause–effect relationships among building and information modeling (BIM)-related risk factors and their impact on the implementation of BIM in construction projects.Design/methodology/approachThis paper draws on previous research to identify and categorize BIM-related risk factors. It then develops a system dynamics (SD) model to examine the cause–effect relationships among these factors leading to issues in BIM implementation.FindingsThe proposed SD model illustrates how nine reinforcing feedback loops provide connections between four categories of risks, namely, technical, information, legal and organizational risks and, consequently, create vicious cycles that threaten the successful implementation of BIM.Originality/valueThis paper is among a few studies that depart from reductionism by taking a holistic approach and demonstrating how the interactions between BIM-related risk factors lead to vicious cycles that threaten the successful implementation of BIM.
Transformational leadership and job performance of Maldives Civil Service employees, mediated by organisational commitment
Authors: Sudha Aminath , Azam S.M. Ferdous , Tham Jacquline 
Published: May 2023

PurposeEmerging research on public administration theory has highlighted the need for public sector managers to become better leaders by inspiring and motivating them to align themselves with their organisation's mission and vision. Therefore, transformational leadership has become increasingly appealing in public administration. This study investigates how transformational leadership affects the job performance of those in the Maldives' civil service. Furthermore, it tests the mediation effect of organisational commitment on the relationship between transformational leadership and the job performance of those working in the Maldives' civil service.Design/methodology/approachThis study adopted a quantitative and cross-sectional design to collect data from 370 employees from different Maldives civil service offices. Data were collected through an online questionnaire, and structural equation modelling was used to test the hypotheses. The mediating effect was tested using bootstrapping.FindingsThe results reveal that transformational leadership did not significantly affect job performance. While a mediation effect was present, the effect size was within a small range.Originality/valueThe results of this study has important implications for the Maldives' civil service from a human resource management perspective and provides insights to policymakers on how to improve leadership in Maldives' civil service institutions. Furthermore, this study contributes significantly to the existing research in understanding the effect of transformational leadership on public sector organisations in Asia and from a developing country's perspective.
Do you want to be roasted? The boundaries of using dark humor as a brand-to-brand communication strategy
Authors: Saavedra Torres Jose Luis , Bhattarai Ashok , Dang Anh , Rawal Monika 
Published: May 2023

PurposeThis study examines the use of dark humor in brand-to-brand communications on social media and its impact on consumers' brand perceptions. In particular, this study looks at roasting messages in which a brand humorously insults its peers.Design/methodology/approachThe authors used a sampling method to recruit 286 participants from the United States. They employed an ANOVA and Tukey's post hoc analysis to test the hypotheses, as well as Hayes' PROCESS to test the mediation and moderation effects, including Johnson–Neyman procedure.FindingsThe authors found that not all customers find roasting messages funny. Rather, consumers' personality and age will influence their perceived humor of the messages and their brand evaluations. Customers who are young and extroverted are likely to believe roasting messages to be funny. They thus perceive the brand to be cooler and more sincere when using such a communication approach, compared to when the brand neutrally interacts with others. Meanwhile, brands may find less success with old and introverted customers.Originality/valueThis research sheds light on how the consumers' perception of humor in a roasting type of brand-to-brand communication has an impact on consumers' psychological perceptions of brand coolness and brand sincerity. To guide practitioners, it explored how the interaction between a consumer's personality and age moderates the aforementioned relationship.
Plants stand still but hide: Imperfect and heterogeneous detection is the rule when counting plants
Authors: Perret Jan , Besnard Aurélien , Charpentier Anne , Papuga Guillaume 
Published: May 2023

Abstract

The estimation of population size and its variation across space and time largely relies on counts of individuals, generally carried out within spatial units such as quadrats or sites. Missing individuals during counting (i.e. imperfect detection) results in biased estimates of population size and trends. Imperfect detection has been shown to be the rule in animal studies, and most studies now correct for this bias by estimating detection probability. Yet this correction remains exceptional in plant studies, suggesting that most plant ecologists implicitly assume that all individuals are always detected.

To assess if this assumption is valid, we conducted a field experiment to estimate individual detection probability in plant counts conducted in 1 × 1 m quadrats. We selected 30 herbaceous plant species along a gradient of conspicuousness at 24 sites along a gradient of habitat closure, and asked groups of observers to count individuals in 10 quadrats using three counting methods requiring progressively increasing times to complete (quick count, unlimited count and cell count). In total, 158 participants took part in the experiment, allowing an analysis of the results of 5024 counts.

Over all field sessions, no observer succeeded in detecting all the individuals in the 10 quadrats. The mean detection rate was 0.44 (ranging from 0.11 to 0.82) for the quick count, 0.59 for the unlimited count (range 0.18–0.87) and 0.74 for the cell count (range 0.46–0.94).

Detection probability increased with the conspicuousness of the target species and decreased with the density of individuals and habitat closure. The observer's experience in botany had little effect on detection probability, whereas detection was strongly affected by the time observers spent counting. Yet although the more time‐consuming methods increased detection probability, none achieved perfect detection, nor did they reduce the effect on detection probability of the variables we measured.

Synthesis. Our results show that detection is imperfect and highly heterogeneous when counting plants. To avoid biased estimates when assessing the size, temporal or spatial trends of plant populations, plant ecologists should use methods that estimate the detection probability of individuals rather than relying on raw counts.
‘The best of both worlds’: The Crisis Communication Think Tank (CCTT) approach to the quest for crisis management keystone
Authors: Jin Yan 
Published: May 2023

AbstractThis insight piece features the Crisis Communication Think Tank (CCTT) at the University of Georgia in the United States. As a thought leadership entity joined by leading practitioners and scholars, the CCTT aims to build academia‐industry collaborations through dialogue on emerging topics and cocreation of evidence‐based advice for next‐generation crisis management theory and practice. This case study, written by the CCTT director and cofounder, walks through the origins of the CCTT, its mission and goals, structure and focus areas, as well as core activities and outputs. It discusses the unique value the CCTT approach brings to cross‐sector crisis communication knowledge generation and dissemination, shedding new light to centre‐based model exploration and innovative crisis management thought leadership development.
Food commodity price changes and consumer welfare in Bangladesh: Valuable lessons for today
Authors: Rahman Kazi Tamim , Shanoyan Aleksan , Hovhannisyan Vardges 
Published: May 2023

AbstractThe recent rise in global food prices threatens many countries worldwide, especially the vulnerable populations. Viable coping strategies can only be designed based on the important policy lessons learned from the experiences of these countries in confronting the similar shocks of 2007–2011. However, the disproportionate effects of these events and the impacts of policy responses remain largely unexplored. We examine the impact of a food price surge and the effectiveness of various mitigating policies in Bangladesh, one of the most populous, densely populated countries in the world that is plagued by poverty. Specifically, we combine individual‐level expenditure survey data with recent advances in consumer theory to examine the welfare consequences across income groups and geographic areas of the country over 2000–2016. Our empirical findings lend support to the hypothesis that the brunt of the price surge was borne by relatively less affluent and rural households, and government poverty alleviation programmes were largely ineffective.
A multidecadal oscillation in precipitation and temperature series is pronounced in low flow series from Puget Sound streams
Authors: Georgiadis Nicholas J. , Baker Joel E. 
Published: May 2023

AbstractIn Pacific Northwest streams, summer low flows limit water available to competing instream (salmon) and out‐of‐stream (human) uses, creating broad interest in how and why low flows are trending. Analyses that assumed linear (monotonic) change over the last ~60 years revealed declining low flow trends in minimally disturbed streams. Here, polynomials were used to model flow trends between 1929 and 2015. A multidecadal oscillation was observed in flows, which increased initially from the 1930s until the 1950s, declined until the 1990s, and then increased again. A similar oscillation was detected in precipitation series, and opposing oscillations in surface temperature, Pacific Decadal Oscillation, and Interdecadal Pacific Oscillation series. Multidecadal oscillations with similar periods to those described here are well known in climate indices. Fitted model terms were consistent with flow trends being influenced by at least two drivers, one oscillating and the other monotonic. Anthropogenic warming is a candidate driver for the monotonic decline, and variation in (internal) climatic circulation for the oscillating trend, but others were not ruled out. The recent upturn in streamflows suggests that anthropogenic warming has not been the dominant factor driving streamflow trends, at least until 2015. Climate projections based on simulations that omit drivers of multidecadal variation are likely to underestimate the range, and rate of change, of future climatic variation.
Stress hyperglycemia ratio is associated with systemic inflammation and clinical outcomes in diabetic inpatients with pneumonia on admission
Authors: Liu Bing , Chen Yu , Yu Liping , Zhou Min 
Published: May 2023

AbstractBackgroundsStress hyperglycemia ratio (SHR) reflects the acute blood glucose change in response to acute illnesses or injuries, including pneumonia. We aimed to investigate the associations of SHR with systemic inflammation and clinical outcomes in diabetic inpatients with pneumonia on admission.MethodsA multicenter and retrospective study was conducted among diabetic inpatients with pneumonia on admission via electronic medical records from 2013 to 2019 in Ruijin Hospital, Shengjing Hospital, and China‐Japan Friendship Hospital.ResultsThe study included 1631 diabetic inpatients with pneumonia on admission. Patients of the fourth quartile (Q4) of SHR on admission showed significantly elevated systemic inflammation compared with those of the first quartile (Q1), second quartile (Q2), or third quartile (Q3) of SHR, including more white blood cells (9.1 × 109/L in Q4 vs 7.6 × 109/L in Q1, 7.9 × 109/L in Q2, and 8.0 × 109/L in Q3, p < .001), higher neutrophil‐to‐lymphocyte ratio (7.0 in Q4 vs 3.6 in Q1, 3.8 in Q2, and 4.0 in Q3, p < .001), higher C‐reactive protein (52.8 mg/L in Q4 vs 18.9 mg/L in Q1, p < .001; 52.8 mg/L in Q4 vs 28.6 mg/L in Q2, p = .002), higher procalcitonin (0.22 ng/mL in Q4 vs 0.10 ng/mL in Q1, 0.09 ng/mL in Q2, and 0.11 ng/mL in Q3, p < .001), and higher D‐dimer (0.67 mg/L in Q4 vs 0.47 mg/L in Q1, 0.50 mg/L in Q2, and 0.47 mg/L in Q3, p < .001). Excluding patients with hypoglycemia on admission in the analyses, there were still distinct J‐shaped associations between SHR and adverse clinical outcomes in patients with different severity of pneumonia, especially in those with CURB‐65 score for pneumonia severity (Confusion, blood Urea nitrogen, Respiratory rate, Blood pressure) ≥ 2. In the multivariable regression model, predictive value for adverse clinical outcomes was higher when SHR was taken as a spline term than as quartiles in all patients (area under curve 0.831 vs 0.822, p = .040), and when SHR as a spline term instead of fasting blood glucose was included in patients with CURB‐65 ≥ 2 (area under curve 0.755 vs 0.722, p = .027).ConclusionsSHR was correlated with systematic inflammation and of J‐shaped associations with adverse clinical outcomes in diabetic inpatients with pneumonia of different severity. The inclusion of SHR in the blood glucose management of diabetic inpatients may be beneficial, especially for the prevention of potential hypoglycemia or the recognition of relative glucose insufficiency in those with severe pneumonia or high hemoglobin A1C.
(Re‐)Packaging Knowledge and The Business of Format: Benjamin Martin's The General Magazine of Arts and Sciences (1755–64)
Authors: Schwalm Helga 
Published: May 2023

AbstractBenjamin Martin was an itinerant lecturer, instrument maker, and the author of a substantial number of textbooks mainly in the sciences. His biggest project, however, was The General Magazine of Arts and Sciences (1755–64), dedicated to the dissemination of knowledge to a broad audience. Rather than study Martin's works with regard to the history of science, this article examines his publications in terms of their highly self‐conscious engagement with form and format. While his textbooks are concerned with economic compression, his periodical General Magazine experiments with a special, unwieldy mode of seriality that brings to the fore the role of format as well as the precarious status of seriality for the purposes of knowledge dissemination.
When Peer Recognition Backfires: The Impact of Peer Information on Subsequent Helping Behavior*
Authors: Wang Pei 
Published: May 2023

ABSTRACTPeer recognition systems (PRS) have gained popularity in recent years as a means for organizations to promote employee helping behavior. However, there are theoretical reasons to believe that peer information that is publicly disclosed in PRS may reduce subsequent helping behavior, and I use an experiment to test my theory. Specifically, I examine a three‐employee setting where an employee (the worker) receives no recognition for helping a coworker (the recognizer) but another coworker (the helper) does. I predict and find that the worker's willingness to subsequently help the recognizer/helper is lower when the worker perceives that the worker's initial help exceeds (vs. subceeds) the helper's. I also find that the worker's perception of fairness mediates the process, and the worker's willingness to help the recognizer has a spillover effect on the worker's willingness to help the helper. My study provides the first empirical evidence of the negative impact that PRS have on helping behavior.
Brain modular connectivity interactions can predict proactive inhibition in smokers when facing smoking cues
Authors: Zhao Haichao , Ge Mengjiao , Turel Ofir , Bechara Antoine , He Qinghua 
Published: May 2023

AbstractProactive inhibition is a critical ability for smokers who seek to moderate or quit smoking. It allows them to pre‐emptively refrain from seeking and using nicotine products, especially when facing salient smoking cues in daily life. Nevertheless, there is limited knowledge on the impact of salient cues on behavioural and neural aspects of proactive inhibition, especially in smokers with nicotine withdrawal. Here, we seek to bridge this gap. To this end, we recruited 26 smokers to complete a stop‐signal anticipant task (SSAT) in two separate sessions: once in the neutral cue condition and once in the smoking cue condition. We used graph‐based modularity analysis to identify the modular structures of proactive inhibition‐related network during the SSAT and further investigated how the interactions within and between these modules could be modulated by different proactive inhibition demands and salient smoking cues. Findings pointed to three stable brain modules involved in the dynamical processes of proactive inhibition: the sensorimotor network (SMN), cognitive control network (CCN) and default‐mode network (DMN). With the increase in demands, functional connectivity increased within the SMN, CCN and between SMN‐CCN and decreased within the DMN and between SMN‐DMN and CCN‐DMN. Salient smoking cues disturbed the effective dynamic interactions of brain modules. The profiles for those functional interactions successfully predicted the behavioural performance of proactive inhibition in abstinent smokers. These findings advance our understanding of the neural mechanisms of proactive inhibition from a large‐scale network perspective. They can shed light on developing specific interventions for abstinent smokers.
US state‐level economic freedom during the COVID‐19 pandemic
Authors: Miozzi Vincent J. , Powell Benjamin 
Published: May 2023

AbstractThe COVID‐19 pandemic led to extensive new government regulations and lockdown policies that significantly reduced economic freedom across US states. Many of these new pandemic‐related regulatory restrictions on economic freedom varied significantly from state to state but are largely missed by the existingEconomic Freedom of North America Report(EFNA). This paper adjusts the Our World in DataCOVID‐19 Stringency Indexinto a state‐level measure oflockdown regulatory freedomand then merges it into the EFNA index to better measure relative economic freedom across US states in 2020. We find significant differences in the relative ranking of economic freedom between states once we adjust for lockdown regulatory restrictions.
Open‐label, randomised controlled trial found that a green banana mixed rice suji diet was most effective for persistent diarrhoea in children in Bangladesh
Authors: Sarmin Monira , Hossain Md Iqbal , Islam Shoeb Bin , Shikha Shamima Sharmin , Alam Nur Haque , Sarker Md Shafiqul Alam , Islam M Munirul , Islam S M Rafiqul , Mahfuz Mustafa , Chisti Mohammod Jobayer , Ahmed Tahmeed 
Published: May 2023

AbstractAimPersistent diarrhoea continues for at least 14 days and kills more children than acute diarrhoea. We assessed whether rice suji, green banana mixed rice suji or 75% rice suji improved persistent diarrhoea in young children.MethodsThis open‐labelled randomised controlled trial was carried out between December 2017 and August 2019 at the Dhaka Hospital of icddr,b, Bangladesh, with 135 children aged 6–35 months with persistent diarrhoea. The children were randomly assigned to green banana mixed rice suji, rice suji or 75% rice suji, with 45 in each group. The primary outcome was the percentage who recovered from diarrhoea by day 5 using an intention‐to‐treat analysis.ResultsThe children's median age was 8 months (interquartile range: 7–10 months). By day 5, the recovery rate was 58%, 31% and 58% for children in the green banana mixed rice suji, rice suji and 75% rice suji groups, respectively. The green banana mixed rice suji group had fewer relapses (7%) than the 75% rice suji group (24%). Enteroaggregative Escherichia coli, rotavirus, norovirus, Enteropathogenic Escherichia coli, astrovirus and Campylobacter were the major pathogens for persistent diarrhoea.ConclusionGreen banana mixed rice suji was the most effective option for managing persistent diarrhoea in young children.
Working with the spoken word: A candid conference conversation and some original ideas
Authors: Hitchings Russell , Latham Alan 
Published: May 2023

AbstractThis paper introduces the collection of nine short articles that make up the inaugural special section of the journal on ‘thinking with methods’. It begins by outlining why a fuller conversation about different ways of handling talk in human geography might be worthwhile. Then it describes a series of conference sessions in which a small group of researchers in this field came together to consider some of the most intriguing excerpts of talk generated by their studies. It ends with an overview of how the following articles that came out of these sessions might productively shake up some of our current working conventions.