bluuebunny/crossref_metadata_2025_split huggingface dataset:
Is the home literacy environment different depending on the media? Paper vs. tablet-based practices
Authors: Jáñez Álvaro , Rosales Javier , De Sixte Raquel , Ramos Marta 
Published: August 2023

AbstractThe Home Literacy model predicts different outcomes depending on formal and informal literacy practices carried out at home. However, this model does not explicitly consider the potential differences that the media (paper vs. tablets) in which these practices are carried out can have on performance. The present study explored this issue. Participants were 136 children aged 6–7 years old and their parents. The different activities performed at home were analysed through reports of the parents, and children were assessed at school for their reading performance (decoding and comprehension). Results showed how formal practices using traditional materials predicted reading comprehension, but informal practices did not predict any performance measure. The digital home literacy environment showed no impact on reading performance, suggesting that two different environments (paper and digital) might exist, each one of them having differential impacts on performance. Implications for research and education are discussed.
Coxiella burnetii infections from animals and ticks in South Africa: a systematic review
Authors: Diseko Letlhogonolo J. , Tsotetsi-Khambule Ana M. , Onyiche ThankGod E. , Ramatla Tsepo , Thekisoe Oriel , Gcebe Nomakorinte 
Published: August 2023

AbstractCoxiella burnetii is a zoonotic intracellular bacterium that is widely distributed and affects domestic animals, wildlife, humans and non-mammalian species. This systematic review was aimed at synthesizing research findings on C. burnetii in both domestic and wild animals of South Africa. The systematic review protocol was registered with Open Society Foundations of systematic reviews (https://doi.org/10.17605/OSF.IO/8WS). PRISMA guidelines were followed to collect and evaluate relevant scientific articles published on C. burnetii infecting domestic and wild animals in South Africa. Published articles were sourced from five electronic databases, namely, Google Scholar, PubMed and ScienceDirect, EBSCO and Scopus. Results showed 11 eligible studies involving four domestic animals, three wild animals and one ectoparasite species from seven provinces across South Africa. The occurrence of C. burnetii infection was high in Ceratotherium simum (white rhinoceros) (53.9%), medium in sheep (29.0%) and low in pigs (0.9%). Limpopo province (26%) had the most recorded infections followed by KwaZulu-Natal (19%) and Free State (3%) had the least reported occurrence of C. burnetii. The current study discovered that there is scarcity of published research on prevalence and distribution of C. burnetii infecting domestic and wild animals in South Africa, and this is of concern as this bacterium is an important zoonotic pathogen of “One Health” importance.
Die ärztliche Wahrnehmung von ME/CFS-Erkrankten (myalgische Enzephalomyelitis/chronisches Fatigue-Syndrom) als „schwierige Patienten“
Authors: Habermann-Horstmeier Lotte , Horstmeier Lukas M. 
Published: August 2023

Zusammenfassung
Hintergrund
Vielen Ärzt:innen in Deutschland ist die Erkrankung myalgische Enzephalomyelitis/chronisches Fatigue-Syndrom (ME/CFS) noch unbekannt. Innerhalb des Gesundheitssystems zeigen sich erhebliche Defizite im Umgang mit ME/CFS-Erkrankten. Dabei spielt die Arzt-Patient-Beziehung (AP-Beziehung) eine zentrale Rolle. Ziel der vorliegenden Studie ist es, aus Sicht der Betroffenen das Auftreten und Verhalten der Ärzt:innen als einen wichtigen Faktor der AP-Beziehung bei ME/CFS genauer zu analysieren.

Methode
Im Rahmen eines explorativen qualitativen Surveys wurden 549 ME/CFS-Erkrankte (> 20 Jahre; n = 456 ♀, n = 93 ♂) mit ärztlicher ME/CFS-Diagnose nach ihren subjektiven Erfahrungen im Hinblick auf das Auftreten und Verhalten der behandelnden Ärzt:innen befragt. Das Sampling erfolgte durch Selbstaktivierung und über das Schneeballprinzip. Der Fragebogen war analog zu einem fokussierten, standardisierten Leitfadeninterview aufgebaut. Die Auswertung der Fragebögen erfolgte im Rahmen einer qualitativen Inhaltsanalyse nach Mayring.

Ergebnisse
Die Proband:innen nannten als einen zentralen Faktor einer problematischen AP-Beziehung bei ME/CFS das geringschätzende, als unangenehm empfundene Auftreten und Verhalten der behandelnden Ärzt:innen. Sie berichteten von fehlender Empathie, Sensibilität und Sozialkompetenz. Viele hatten das Gefühl, von den Ärzt:innen nicht ernstgenommen und als „schwierige Patient:innen“ eingeordnet zu werden. Weder würden ihre interaktionellen Grundbedürfnisse berücksichtigt, noch gebe es eine Beziehung auf Augenhöhe. Zudem sei eine Abwehrhaltung den Patient:innen gegenüber spürbar. Darunter leide die AP-Beziehung.

Schlussfolgerungen
Das Auftreten und Verhalten der konsultierten Ärzt:innen ist aus Sicht der ME/CFS-Erkrankten ein zentraler Aspekt einer von ihnen als problematisch erlebten AP-Beziehung. Auf der Basis dieser Erkenntnisse sollen nun weitere Faktoren analysiert werden, die das AP-Verhältnis bei ME/CFS charakterisieren. Zudem sollen die gesundheitlichen Auswirkungen eines problematischen AP-Verhältnisses aus Sicht der Betroffenen untersucht werden.
Vitamin and Mineral Deficiency 12 Years After Roux-en-Y Gastric Bypass a Cross-Sectional Multicenter Study
Authors: Bjerkan Kirsti K. , Sandvik Jorunn , Nymo Siren , Græslie Halvor , Johnsen Gjermund , Mårvik Ronald , Hyldmo Åsne A. , Kulseng Bård Eirik , Sommerseth Sandra , Høydal Kjetil Laurits , Hoff Dag Arne L. 
Published: August 2023

Abstract
Purpose
Micronutrient deficiencies are common after Roux-en-Y gastric bypass (RYGB). This study explores whether vitamin and mineral deficiency was associated with adherence to recommended supplementation 12 years after RYGB.

Materials and Methods
The cross-sectional Bariatric Surgery Observation Study (BAROBS) was conducted in 2018–2020 at three hospitals in Central Norway. We report data on 490 patients’ self-reported adherence to recommended supplements and vitamin and mineral levels in the blood. The patients, who had RYGB between 2003 and 2009, were recommended an over-the-counter multivitamin-mineral supplement, calcium/vitamin D (1000 mg/20 µg) and vitamin B12 injections (reimbursed), since bariatric supplements were not available then.

Results
Mean (SD) age was 40.1 ± 9 years at RYGB, and time to follow-up 11.7 ± 1.6 years. Of 490 patients, 393 (80%) were women. Among 361 (74%) patients’ adherent to multivitamin-mineral supplements; folate, vitamin B2, and vitamin B6 deficiency were present in 39 (11%), 103 (29%), and 63 (17%) patients, respectively. The same deficiencies occurred in 44 (34%), 67 (52%), and 67 (52%) patients’ non-adherent to recommendations. Although 466 (95%) patients reported adherence to vitamin B12 supplements, sub-optimal levels were found in 73 (16%) patients.
Though 336 (69%) patients adhered to calcium/vitamin D supplements (1000 mg/20 µg), sub-optimal vitamin D levels (< 75 nmol/l) were found in 174/336 (52%) adherent patients and 120/154 (78%) non-adherent patients.

Conclusion
Twelve years after RYGB, adherence to supplements, though in sub-optimal doses of new recommendations, decreases the probability of vitamin and mineral deficiency, especially for thiamine, vitamin B2, vitamin B6, folate, vitamin B12, and vitamin D, but does not eliminate it.

Graphical Abstract
Sailboat navigation control system based on spiking neural networks
Authors: Giraldo Nelson Santiago , Isaza Sebastián , Velásquez Ricardo Andrés 
Published: August 2023

AbstractIn this paper, we presented the development of a navigation control system for a sailboat based on spiking neural networks (SNN). Our inspiration for this choice of network lies in their potential to achieve fast and low-energy computing on specialized hardware. To train our system, we use the modulated spike time-dependent plasticity reinforcement learning rule and a simulation environment based on the BindsNET library and USVSim simulator. Our objective was to develop a spiking neural network-based control systems that can learn policies allowing sailboats to navigate between two points by following a straight line or performing tacking and gybing strategies, depending on the sailing scenario conditions. We presented the mathematical definition of the problem, the operation scheme of the simulation environment, the spiking neural network controllers, and the control strategy used. As a result, we obtained 425 SNN-based controllers that completed the proposed navigation task, indicating that the simulation environment and the implemented control strategy work effectively. Finally, we compare the behavior of our best controller with other algorithms and present some possible strategies to improve its performance.
Predicting Changes in Systolic and Diastolic Blood Pressure of Hypertensive Patients in Indonesia Using Machine Learning
Authors: Nuryunarsih Desy , Herawati Lucky , Badi’ah Atik , Donsu Jenita Doli Tine , Okatiranti  
Published: August 2023

Abstract
Purpose of Review
This retrospective study investigated factors that influence the occurrence of decreased systolic and diastolic blood pressure including sociodemographic and economic factors, hypertension duration, cigarette consumption, alcohol consumption, duration of smoking, type of cigarettes, exercise, salt consumption, sleeping pills consumption, insomnia, and diabetes. These factors were applied to predict the reality of systolic and diastolic decrease using the machine learning algorithm Naïve Bayes, artificial neural network, logistic regression, and decision tree.

Recent Findings
The increase in blood pressure, both systolic and diastolic, is very harmful to the health because uncontrolled high systolic and diastolic blood pressure can cause various diseases such as congestive heart failure, kidney failure, and cardiovascular disease. There have been many studies examining the factors that influence the occurrence of hypertension, but few studies have used machine learning to predict hypertension.

Summary
The machine learning models performed well and can be used for predicting whether a person with hypertension with certain characteristics will experience a decrease in their systolic or diastolic blood pressure after treatment with antihypertensive drugs.
Adoption, Fostering, and Parental Absence in Vanuatu
Authors: Brandl Eva , Emmott Emily H. , Mace Ruth 
Published: August 2023

AbstractAlloparenting, wherein people provide care to children who are not their biological offspring, is a key aspect of human child-rearing. In the Pacific, many children are adopted or fostered by custodial alloparents even when both biological parents are still alive. From a behavioral ecology perspective, such behaviors are puzzling: why parent someone else’s child at your expense? Furthermore, little is known about how these arrangements are made in Pacific Islander societies today, who provides care, and what kinds of outcomes fostered children experience. A better understanding of these proximate factors may help reveal the ultimate drivers behind custodial alloparenting. Here, we report findings from a survey carried out with the caregivers of 282 children in rural areas of Vanuatu, an island nation in Melanesia. Most fostered and adopted children lived with relatives such as aunts, uncles, and grandparents (87.5%) rather than unrelated caregivers, with a strong preference for maternal kin. The most common reasons for these arrangements were that the parents had separated (16.7%), were engaging in labor migration (27.1%), or a combination of both (27.1%). Results for investment in children’s education and their educational outcomes were mixed, although children removed from crisis situations did more poorly than children removed for aspirational reasons. Our findings suggest that custodial alloparenting helps families adapt to socioeconomic transitions and changing marriage practices. Outcomes may depend on a range of factors, such as the reason children were transferred out of the natal home to begin with.
Challenges in prevention, early detection, and management of febrile neutropenia in adult patients with solid tumors
Authors: Popov Petar 
Published: August 2023

SummaryFebrile neutropenia (FN) is a common oncologic emergency where quick patient assessment and prompt initiation of antimicrobial treatment is crucial. Guidelines provide detailed recommendations on prevention and treatment; however, their real-world implementation can prove to be difficult. Score systems for outcome risk are effective in identifying low-risk patients with FN. After initiation of therapy, regular re-evaluation of antimicrobial treatment is necessary, and further diagnostic studies should be tailored to each patient. Use of granulocyte colony-stimulating factor (G-CSF) prophylactically in chemotherapy regimens with intermediate FN risk as well as therapeutically in patients with manifest FN is variable in clinical practice and needs to be better defined. Future steps of reducing risk of FN involve investigating underlying genetic factors. Regarding early detection of FN, patient education is paramount. This short review gives an overview of current guidelines and highlights key challenges in management of FN.
Improved Prognostic Performance of Right Atrial Pressure-Corrected Cardiac Power Output in Pulmonary Hypertension and Heart Failure with Preserved Ejection Fraction
Authors: Wu Yihang , Tian Pengchao , Liang Lin , Chen Yuyi , Feng Jiayu , Huang Boping , Huang Liyan , Zhao Xuemei , Wang Jing , Guan Jingyuan , Li Xinqing , Zhang Jian , Zhang Yuhui 
Published: August 2023

AbstractCardiac power output (CPO) is a powerful predictor of adverse outcomes in heart failure (HF). However, the original formula of CPO included the difference between mean arterial pressure and right atrial pressure (RAP). The prognostic performance of RAP-corrected CPO (CPORAP) remains unknown in heart failure with preserved ejection fraction (HFpEF). We studied 101 HF patients with a left ventricular ejection fraction > 40% who had pulmonary hypertension due to left heart disease. CPORAP was significantly more discriminating than CPO in predicting outcomes (Delong test, P = 0.004). Twenty-five (24.8%) patients presented with dis-concordantly high CPORAP and low CPO when stratified by the identified CPORAP threshold of 0.547 W and the accepted CPO threshold of 0.803 W. These patients had the lowest RAP, and their cumulative incidence was comparable with those with concordantly high CPO and CPORAP (P = 0.313). CPORAP might identify patients with right ventricular involvement, thereby providing better prognostic performance than CPO in HFpEF.
Graphical Abstract
A review of acoustofluidic separation of bioparticles
Authors: Hossein Fria , Angeli Panagiota 
Published: August 2023

AbstractAcoustofluidics is an emerging interdisciplinary research field that involves the integration of acoustics and microfluidics to address challenges in various scientific areas. This technology has proven to be a powerful tool for separating biological targets from complex fluids due to its label-free, biocompatible, and contact-free nature. Considering a careful designing process and tuning the acoustic field particles can be separated with high yield. Recently the advancement of acoustofluidics led to the development of point-of-care devices for separations of micro particles which address many of the limitations of conventional separation tools. This review article discusses the working principles and different approaches of acoustofluidic separation and provides a synopsis of its traditional and emerging applications, including the theory and mechanism of acoustofluidic separation, blood component separation, cell washing, fluorescence-activated cell sorting, circulating tumor cell isolation, and exosome isolation. The technology offers great potential for solving clinical problems and advancing scientific research.
Normative Diagrams as a Tool for Representing Legal Systems
Authors: Sasdelli Diogo , Trivisonno Alexandre Travessoni Gomes 
Published: August 2023

AbstractThe paper at hand introduces and discusses a diagrammatic method to represent legal norms first developed by the second author. It is shown how this method can be used to represent not only norms and argument forms originating from classic legal methodology (legal subsumption, analogy, appeal to the contrary), but also more complex legal-theoretical phenomena, especially legal antinomies. Beyond its didactic virtues, the diagram is a useful theoretical tool for investigating how norms interact with each other and how singular actions can be considered as satisfying or violating a given norm.
Force capacity of trunk muscle extension and flexion in healthy inactive, endurance and strength-trained subjects—a pilot study
Authors: Schönau Tim , Anders Christoph 
Published: August 2023

AbstractRecreational sports are becoming increasingly important in overcoming the drawbacks of our modern sedentary lifestyle. We wanted to know whether ambitious strength or endurance training has a systematic effect on the maximum strength capacity of the trunk muscles compared to no sport at all. We investigated two groups of physically active men who practised either endurance (ET; cycling and triathlon, n = 13) or strength training (ST; power lifting, n = 13), and a group of healthy physically inactive men (control [C], n = 12). Training intensity was at competition level in both active groups. All participants performed isometric maximum voluntary contractions in flexion and extension direction. Independent of force direction maximum torque levels were highest for the ST group (p < 0.001 vs. ET and C), but after normalizing to the subject’s upper body weight these differences decreased, together with a drop in significance levels (extension: p < 0.01 vs. C; flexion: p < 0.05 vs. ET; p < 0.01 vs. C). With respect to the ratio between extension and flexion maximum forces due to the small group size no systematic differences could be detected between the groups, but effect sizes imply relevant effects (ET vs. ST: d = 0.588, ST vs C: d = −0.811). The results of this pilot study indicate that ST show higher functional force capacity values for flexion compared to the other groups. For extension, ST and ET did not differ. These results imply relevant differences for the extension to flexion force ratio.
Effects of metalloprotease ADAMTS12 on cervical cancer cell phenotype and its potential mechanism
Authors: Zou Ruanmin , Gu Ruihong , Tu Xinyu , Chen Jiani , Liu Songjun , Xue Xiangyang , Li Wensu , Zhang Yuyang 
Published: August 2023

AbstractADAMTS12 is a gene widely expressed in human tissues. We studied the expression level of ADAMTS12 in cervical cancer tissue and its relationship with clinicopathological features. We also explored the function of ADAMTS12 in cervical cancer cells and its underlying mechanisms. We found the higher expression level of ADAMTS12 in cancer tissues, which was associated with the worse overall survival rate. The immunofluorescence assay showed that the cytoplasm of cervical cancer cells is the main expression site of ADAMTS12. Overexpression of ADAMTS12 in HeLa and CaSki cells prominently promoted the cell proliferation, migration and invasion. We found that 2032 genes were correlated with ADAMTS12, which was mainly related to extracellular matrix, TGF-β signaling pathway. The phosphorylation levels of mTOR and 4E-BP1 were upregulated in ADAMTS12-overexpressing cells. Co-Immunoprecipitation combined with protein mass spectrometry showed that TGF-β signaling pathway-related proteins interacting with ADAMTS12 were screened from HeLa cells with ADAMTS12 overexpression. Therefore, we concluded that ADAMTS12 may affect the mTOR signaling pathway through the interacting with TGF-β1, and then affect the biological function of cervical cancer cells.
One-year safety and effectiveness of the Agent paclitaxel-coated balloon for the treatment of small vessel disease and in-stent restenosis
Authors: Nakamura Masato , Isawa Tsuyoshi , Nakamura Shigeru , Ando Kenji , Namiki Atsuo , Shibata Yoshisato , Shinke Toshiro , Ito Yoshiaki , Fujii Kenshi , Shite Junya , Kozuma Ken , Saito Shigeru , Yamaguchi Junichi , Yamazaki Seiji , Underwood Paul , Allocco Dominic J. 
Published: August 2023

AbstractThe Agent device consists of a semi-compliant balloon catheter, which is coated with a therapeutic low-dose formulation of paclitaxel (2 µg/mm2) blended with an inactive excipient acetyl-tri-n-butyl citrate (ATBC). AGENT Japan SV is a randomized controlled study that enrolled 150 patients from 14 Japanese sites treated with Agent or SeQuent Please paclitaxel-coated balloon. This study also includes a single-arm substudy evaluating the safety and effectiveness of Agent in patients with in-stent restenosis (ISR). Patients with a single de novo native lesion (lesion length ≤ 28 mm and reference diameter ≥ 2.00 to  < 3.00 mm) were randomized 2:1 to receive either Agent (n = 101) or SeQuent Please (n = 49). The ISR substudy enrolled 30 patients with lesion length ≤ 28 mm and reference diameter ≥ 2.00 to  ≤ 4.00 mm. In the SV RCT, target lesion failure (TLF) at 1 year occurred in four patients treated with Agent (4.0%) versus one patient with SeQuent Please (2.0%; P = 1.00). None of the patients in either treatment arm died. There were no significant differences in the rates of myocardial infarction, target lesion revascularization and target lesion thrombosis through 1 year. In the ISR substudy, the 1-year rates of TLF and target lesion thrombosis were 6.7% and 0.0%, respectively. These data support the safety and effectiveness of the Agent paclitaxel-coated balloon in patients with small vessels and ISR.
Assessing surface water uses by water quality index: application of Qalyubia Governorate, Southeast Nile Delta, Egypt
Authors: Gabr Mohamed Elsayed , Soussa Hoda 
Published: August 2023

AbstractIn this study, water quality index (WQI) was applied at one of the most crowded Nile reaches surroundings in Egypt to investigate its impacts on different water uses. Twelve sites are selected for monitoring (S1–S12) within the irrigation system network of the Qalyubia Governorate, and water samples from these locations in 2021 were collected, analyzed, assessed, and compared to analyze water quality data collected in 2014 in light of the Egyptian permissible water quality limits regarding the drinking and irrigation uses. These two main sets of data were chosen to emphasize the change in WQI within this period, denoting the time before the epidemic COVID19 and after the lockdown of the epidemic in 2021 in the study area. Fifteen physicochemical water parameters were measured. The results show that the WQI for the surface water monitoring sites is classified as good quality except for S8, which showed a poor water quality type. In addition, S2 has recorded a BOD concentration of 6.4 mg/L, which is slightly above the Egyptian limit (6 mg/L). Also, S8 recorded a slight increase in Fe, Mn, and F compared to permissible concentrations. TDS varies between 258.08, 318, and (249 ± 18.2) mg/L for minimum, maximum, and average ± standard deviation, respectively, indicating suitable irrigation water. The study suggests that surface water can be used to irrigate crops, but it should be purified before being used for drinking purposes. A comparison of the water quality parameters for the years 2014 and 2021 for the sites S1, S4, S5, S7, S9, and S10 reveals an increase in water quality from poor (2014) to good (2021). Therefore, the poor water quality in 2014 can be referred the effect of inadequate sewage treatment, industrial wastewater flows, and urban runoff discharge, which had been decreased with the decrease in different activities during the epidemic period and lockdown.