bluuebunny/crossref_metadata_2025_split huggingface dataset:
Geometric and Radiometric Recording of Prehistoric Graphic Expression: the case of Peña Tu (Asturias, Spain)
Authors: Teira Luis , Bayarri Vicente , Ontañón Roberto , Castillo Elena , Arias Pablo 
Published: September 2023

Abstract
In the studies on Prehistoric Graphic Expression, there are recurrent discussions about the tracings generated by different observers of the same motif. Methodological issues concerning the role of archaeological imaging are often implied within those debates. Do the tracings belong to the observational data exposition chapter, or are they part of the interpretative conclusions? How can the current technological scenario help solve these problems? In 2017, we conducted new documentation of the Peña Tu rock shelter, a well-known site with an intriguing post-palaeolithic graphic collection documented on several occasions throughout the 20th century. Our objective was to provide quantifiable and, if possible, objective documentation of the painted and engraved remnants on the shelter's surface. To achieve this, we employed two data capture strategies. One strategy focused on analyzing the vestiges of paintings using a hyperspectral sensor, while the other centred on the geometric definition of engravings and the rock support, utilizing photogrammetric techniques and laser scanning. These approaches presented various parallax challenges. Despite these challenges, our results were highly satisfactory. We resolved uncertainties regarding the formal features of specific designs that had been subject to debate for a long time. Additionally, we discovered previously unpublished areas with traces of paintings. Lastly, we developed a map highlighting recent alterations and deteriorations, providing a valuable tool for assessing the site's preservation status. In conclusion, by employing advanced technology and comprehensive documentation methods, we significantly contributed to understanding and preserving the prehistoric graphic expressions at the Peña Tu rock shelter.
Low-Cost and High-Performance Abnormal Trajectory Detection Based on the GRU Model with Deep Spatiotemporal Sequence Analysis in Cloud Computing
Authors: Tang Guohao , Zhao Huaying , Yu Baohua 
Published: September 2023

Abstract
Trajectory anomalies serve as early indicators of potential issues and frequently provide valuable insights into event occurrence. Existing methods for detecting abnormal trajectories primarily focus on comparing the spatial characteristics of the trajectories. However, they fail to capture the temporal dimension's pattern and evolution within the trajectory data, thereby inadequately identifying the behavioral inertia of the target group. A few detection methods that incorporate spatiotemporal features have also failed to adequately analyze the spatiotemporal sequence evolution information; consequently, detection methods that ignore temporal and spatial correlations are too one-sided. Recurrent neural networks (RNNs), especially gate recurrent unit (GRU) that design reset and update gate control units, process nonlinear sequence processing capabilities, enabling effective extraction and analysis of both temporal and spatial characteristics. However, the basic GRU network model has limited expressive power and may not be able to adequately capture complex sequence patterns and semantic information. To address the above issues, an abnormal trajectory detection method based on the improved GRU model is proposed in cloud computing in this paper. To enhance the anomaly detection ability and training efficiency of relevant models, strictly control the input of irrelevant features and improve the model fitting effect, an improved model combining the random forest algorithm and fully connected layer network is designed. Experimental results based on the GeoLife GPS Trajectories dataset demonstrate that the improved GRU network model in cloud computing significantly outperforms other network architectures in terms of training cost, detection performance and generalization ability.
Appraising the impact of automobile mechanic workshop activities on the soil’s heavy metals contamination level in Isoko Community, Niger Delta region of Nigeria
Authors: Akpoedafe Thomas , Owamah T. O. , Atikpo H. O. , Ikpeseni sunday , Alumona Chris , Unuafe SUNDAY , ORUGBA HENRY 
Published: September 2023

Abstract
There is increasing concern on environmental pollution caused by anthropogenic actions. This research was aimed at evaluating the effect of leachates from vehicle mechanic workshops, on the soil’s heavy metals pollution level. A total of 20 soil samples (10 topsoil and 10 subsoil) were collected from 9 active clusters of automobile mechanic workshops, and a reference site. Eight heavy metals – cadmium “Cd”, chromium “Cr”, copper “Cu, iron “Fe”, lead “Pb”, manganese “Mn”, nickel “Ni” and zinc “Zn”- concentration were measured in the soil samples in accordance with ASTM International standard. Thereafter these pollution indices – contamination factor (CF), single pollution index (SPI) and pollution load index (PLI) were used to evaluate the degree of heavy metals pollution in the region’s soil. The results revealed that the mean Cd, Cr, Cu, Fe, Pb, Mn, Ni and Zn concentration in the topsoil samples was 0.172 mg/kg, 0.36 mg/kg, 0.64 mg/kg, 159.40 mg/kg, 0.415 mg/kg, 1.39 mg/kg, 0.745 mg/kg and 2.184 mg/kg respectively. While the Cd, Cr, Cu, Fe, Pb, Mn, Ni and Zn content in the subsoil was 0.139 mg/kg, 0.274 mg/kg, 0.462 mg/kg, 138.90 mg/kg, 0.349 mg/kg, 1.144 mg/kg, 0.586 mg/kg and 1.793 mg/kg respectively. Furthermore, the pollution indices results indicated that the soil had low level of heavy metals contamination, and can be considered safe for plants and animals. Accumulation of toxic metals in the soil is a major environmental threat; therefore there is need to monitor the activities of automobile mechanics in Nigeria by environmental protection agencies.
The effect of sequential embryo transfer on pregnancy outcomes in patients with repeated implantation failure, A meta analysis
Authors: Xingnan Liu , Na Zhang 
Published: September 2023

Abstract
Purpose: This meta-analysis aims to evaluate the effectiveness of sequential embryo transfer (cleavage embryo transfer followed by blastocyst embryo transfer in the same cycle) in patients with repeated implant failure.
Methods: The research was designed in the PICOS format. The search was performed in the PubMed, Web of Science, Cochrance Library and Embase databases. The time range was from library building to June 20, 2023. Ultimately, The randomized controlled trial experiments (RCT) comparing sequential embryo transfer groups and control groups on pregnancy outcomes in RIF patients met the inclusion criteria and were included in the meta analysis. Five RCT studies and 873 repeated implantation failure patients were enrolled. Risk ratio (RR) and 95% confidence interval (CI) were calculated. The primary outcome measures were implantation rate and clinical pregnancy rate. The secondary indicators were miscarriage rate, multiple pregnancy rate, chemical pregnancy rate and ongoing pregnancy rate. The screening of articles was performed with Endnote, and data were analyzed with Review Manager 5.4.
Results: Five RCT articles were finally included. Our results showed that compared with control group, sequential embryo transfer was associated with higher implantation rate (RR= 1.66, 95% CI: 1.34- 2.05, P< 0.00001, I2= 0.0%) and clinical pregnancy rate (RR= 1.58, 95% CI: 1.31- 1.91, P< 0.00001, I2= 18%). And there were no statistically significant differences in miscarriage rate, multiple pregnancy rate, chemical pregnancy rate and ongoing pregnancy rate.
Conclusion: Sequential embryo transfer, contributes to higher implantation rate and clinical pregnancy rate in RIF patients, which is instructive for future clinical work.
Identification novel salty-enhancing peptides from sea cucumber collagen: AlphaFold2 modeling and molecular simulation
Authors: Bu Ying , Zhou Yang , Sun Chaonan , Zhu Wenhui , Li Xuepeng , Li Jianrong 
Published: September 2023

Abstract

This study aimed to extract novel salty-enhancing peptides from the collagen of sea cucumber. The model of the transmembrane channel-like 4 (TMC4) salt taste receptor was constructed by AlphaFold2 de novo model, and the interaction between peptides and salt taste receptor was studied by molecular dynamics (MD) simulation. The results revealed that 99.4% of amino acid residues in the Ramachandran Plot of the TMC4 model resided within the allowed region, thereby substantiating the rationality of the model. The molecular docking results indicated that Gln 279, Glu 92, and Lys 278 may be the key amino acids binding to the TMC4 receptor. The CSRH and KDINNRF showed significant enhancement in saltiness compared to the control group (2.62 ± 0.04), with saltiness values of 3.01 ± 0.00 and 2.86 ± 0.04, respectively. In addition, MD simulation results showed that TMC4 saltiness receptors formed stable RMSD and Rg with salty-enhancing peptides at 0–25 ns simulation time. This study verified that CSRH and KDINNRF are effective salty-enhancing peptides, and also provided a theoretical basis for the discovery of new salty-enhancing peptide resources in marine organisms.
Spontaneous Rupture as the Initial Symptom of Primary Hepatic Carcinosarcoma: A Thorough Case Report with Follow-up Data and Literature Review
Authors: Zhao Zonglei , Wang Tao , Liu Zheng , Zhao Mingwei , Zhang Yang , Cao Xuefeng , Zhang Xingyuan 
Published: September 2023

Abstract
Background
Primary hepatic carcinosarcoma (HCS) is an extremely rare malignant tumor that is composed of a mixture of carcinomatous and sarcomatous elements. However, there have been few reported cases, especially with sufficient records to describe imaging and pathological features, posing the diagnosis, treatment, and prognosis of HCS significant challenges for clinical physicians. Here, we report and review a case of HCS, including combined imaging findings, analysis of pathology and immunohistochemistry, and clinical features, which will be beneficial for future diagnosis, improving clinical management, and exploring effective treatments to improve survival for HCS patients.
Case presentation:
Here, we report a case of HCS with spontaneous rupture as the initial symptom in a 77-year-old elderly male who was admitted with right upper abdominal pain for 8 days. The computed tomography (CT) enhancement scan revealed a massive, enhanced shadow primarily outside of the liver; hypodense fluid was seen around the liver, which was initially considered a spontaneous rupture of giant primary liver cancer. The patient underwent a laparotomy, but postoperative pathology unexpectedly showed an HCS with spontaneous rupture. Although the primary lesion was successfully removed during the surgery, the tumor recurred only 5 months after surgery and was approximately as large as the initial tumor. Unfortunately, the patient was not a candidate to undergo surgery to remove the recurrent tumor. Just 9 days after his second discharge, the patient passed away at home. His postoperative survival time was only 5 months.
Conclusions
HCS is an extremely rare malignant tumor with high malignancy and poor prognosis, for which there is still no effective therapy. This study demonstrates the imaging characteristics and pathological results of an HCS patient whose initial symptom was a spontaneous rupture hemorrhage and reviews the clinical features of HCS previously reported in the literature. Additional similar cases are needed to clarify the exact diagnosis, and treatment of this disease.
Digital Transformation of the Higher Education System: Directions and Risks
Authors: Shelepaeva A. Kh. 
Published: September 2023

Purpose of research. The higher education system is undergoing changes under the influence of an increasing number of IT solutions used. Transformation changes take place at the organizational, technological, legal, and regulatory levels of management. Each of the directions affects the features of the functioning and development of the higher education system. In the process of their implementation, there are also deviations, risks that need to be, if not eliminated, then at least minimized. The article describes four main directions of development: technical, technological, instrumental, and educational. The types of risks associated with each of the described areas are also highlighted.Materials and methods. A set of methods was used in the paper: bibliographic (selection of articles by keywords); bibliometric (quantitative characteristics by time parameters); content analysis (method of studying the content of articles); evaluation of keyword queries using Internet services.Results. An analysis of queries by keywords showed that interest in the issues of digitalization and digital transformation of higher education arose later than in the system of general secondary education. There is a tendency to adapt successful models of digitalization of secondary education and business areas to the activities of the higher education system. Without considering the peculiarities of the functioning and development of the higher education system, we can get negative consequences expressed in different types of risks. The paper highlights financial, form-major, technological, operational, strategic, cognitive, and social risks.Conclusion. One of the key problems highlighted in the process of analyzing developments in the field of digital transformation of the education system is the consideration of digitalization as means, and not as a catalyst for systemic changes in all areas of activity. Point solutions will not allow you to fully realize the potential of digital solutions. When considering the problems of digitalization and digital transformation, higher education systems are often guided by successful models in the field of secondary general education and / or business environment, which can contribute to the formation of negative consequences when adapting approaches without considering their own specifics.
Radiological Features of Rare Non-odontogenic Lesions of the Jaws
Authors: Akkoyunlu Murat , Bulgurcu Emre , Delilbası Cagrı , Sabir Nuran 
Published: September 2023

Background:
The jaws can be affected by several lesions that manifest in the oral cavity, but little is known about non-odontogenic benign and malignant lesions and their radiological findings.

Introduction:
Our aim was to discuss the imaging findings of non-odontogenic jaw lesions to help the surgeon in the diagnosis and formulating a differential diagnosis for this vast spectrum of jaw lesions with overlapping clinical and imaging appearances.

Methods:
CT and MR images of the mandible, maxillofacial region, and neck were retrieved from the archive of the Radiology Department of Pamukkale University for the duration between 2012-2023 and assessed.

Results:
A total of 8125 CT and MR images were retrospectively analyzed. The mean age of the patients was 39.5 years in females and 43.2 in males, with a range varying from 15 to 72 years. Histopathologically approved benign and malignant non-odontogenic lesions were detected in only 19 patients out of 8125 images (0.23%). Osteomyelitis and abscess were the most common (n=3; 0.03%), followed by two cases (n=2; 0.02%) of each fibrous dysplasia, hemangioma, osteosarcoma, squamous cell carcinoma, and multiple myeloma, and one case (n=1; 0.01%) of each ossifying fibroma, osteoma, lymphoma, metastasis, and solitary bone cyst.

Conclusion:
Although non-odontogenic benign and malignant lesions of the jaw are rare, awareness of the radiological features of these lesions plays an important role in their diagnosis and management.
Review of the Efficacy and Safety of Cannabidiol with a Focus on
Children and Adolescents in the Treatment of Psychiatric
Symptoms and Disorders
Authors: Sun Amanda Yuan , Sullivan Aimee , Leffler Jarrod M , Hammond Christopher J , Hulvershorn Leslie , Miller Leslie 
Published: September 2023

Abstract:
Cannabidiol (CBD) is a plant-derived cannabinoid found in cannabis and
hemp plants with broad psychopharmacologic effects and poorly understood
mechanisms of action that may include antioxidant and anti-inflammatory
properties and central nervous system (CNS) modulation of endocannabinoid,
glutamatergic, and serotonergic neurotransmission. This article reviews existing
data on the safety and efficacy of CBD for mental and physical health indications in
the pediatric population and for psychiatric disorders in adults, with a focus on
clinical trials. Searches of PubMed and PsycINFO for articles through October
2021 focused on clinical trials on “cannabidiol” and “seizure” or “psychiatry” in
youth and adults, identifying 686 articles that were then screened and evaluated for
relevance. Research into the safety and efficacy of CBD led to the United States
Food and Drug Administration's approval of Epidolex, a purified pharmaceuticalgrade
CBD medicine, for treating drug-resistant seizures in Dravet syndrome,
Lennox-Gastaut syndrome and tuberous sclerosis complex. Beyond treatment for
rare seizure disorders, CBD has received growing public interest in recent years as
a “natural” treatment for various other medical and psychiatric conditions, resulting
in a rapidly expanding multi-billion-dollar US market for CBD dietary/health
supplements and a growing number of Americans reporting regular use. However,
the growing demand and broad claims of purported benefits have greatly outpaced
the body of literature substantiating its use. Further, limited safety data in pediatric
populations, drug-to-drug interactions between CBD and prescribed medications,
and issues related to mislabeling and contamination have blunted enthusiasm for
CBD in the pediatric healthcare community and indicate a need for additional
research.
¿Desplegando resiliencia?: Agricultura familiar y sistemas alimentarios en contexto de Covid-19
Authors: Rengifo Briceño Gabriela , Loli Meléndez Fiorella 
Published: September 2023

La Municipalidad Provincial de Huancayo participa del Pacto de Milán, un acuerdo para promover sistemas alimentarios sostenibles que promueve la producción agroecológica. Junín es la primera región, a nivel nacional, en que se ejecuta un piloto de compras públicas de productos frescos para el Programa Nacional de Alimentación Escolar Qali Warma.
Durante los meses más críticos de la pandemia, el precio de la papa en el mercado Maltería de Huancayo llegó a caer hasta los 30 céntimos el kilo y el precio en chacra hasta 10 céntimos. A pesar que las personas naturales representan el grueso del número de las unidades agropecuarias, la mayoría de la superficie agropecuaria es manejada por comunidades campesinas. Así el 88.48% de superficie agropecuaria en Concepción es manejada por comunidades campesinas, el 86.52% en Huancayo, el 81.36% en Jauja, el 75.65% en Tayacaja y el 62.99% en Chupaca.
El porcentaje de unidades agropecuarias en las cinco provincias es menor a 3 hectáreas, siendo Tayacaja la que presenta un 83% de tierras menores a 3 hectáreas y Huancayo con un 91%.
Current issues of anti-dumping and safeguard investigations during martial law
Authors: Herasymchuk Ye 
Published: September 2023

The article is devoted to the issues of conducting anti-dumping and safeguard investigations in Ukraine under martial law. The author analyses the current practice of the Ministry of Economy of Ukraine in conducting trade investigations in terms of determining the time limits for procedural stages of investigations within the competence of the authority, which demonstrates that the investigating authority violates the rights of the parties concerned in trade investigations, some of which are still unresolved.The purpose of the article is to study the legality of the actions of the Ministry of Economy of Ukraine with regard to postponement of deadlines within investigations and compliance with the World Trade Organization Agreements governing certain types of trade investigations, and to prepare recommendations for further actions of the Ministry of Economy of Ukraine within its competence.
It is concluded that the Ministry of Economy and the Interdepartmental Commission on International Trade have discretionary powers to determine certain terms of investigations and make decisions based on their results. The author concludes that determining the time limits for procedural stages of investigations remains within the discretionary powers of the Ministry of Economy of Ukraine as long as the time limits for conducting trade investigations set out in Ukrainian legislation are not violated. The author also examines the legal consequences of violation of these deadlines.The author has prepared conclusions and recommendations on conducting trade investigations and making decisions based on their results in case of violation of the time limits established by the legislation of Ukraine, the key of which is that further conduct of an anti-dumping or safeguard investigation after such violation is illegal, therefore, the Interdepartmental Commission on International Trade, upon the submission of the Ministry of Economy of Ukraine, should terminate the investigation without taking any measures.
Regulatory and legal consolidation of the application of digital technologies to ensure the criminology security of society
Authors: Beneskul A. 
Published: September 2023

The article examines the directions of application of digital technologies in various spheres of life of civil society and the state within the framework of ensuring criminological security of the state. Separate legal acts containing norms regarding the necessity of using various digital technologies and their significance in the development of the rule of law have been analyzed. The author noted the need not only to create a legal basis for the use of digital technologies, but also the importance of developing a system of effective measures to effectively combat crimes committed with the use of digital technologies. Attention is drawn to the problem of the lack of sufficient legal bases related to the understanding of digital crime, which requires detailed study and clear regulatory regulation. Also, the article carries out a comprehensive study of the field of use of digital technologies, as well as outlines directions for solving criminological tasks, which involve the definition of «criminal offenses committed with the use of digital technologies» and the search for new forms and means of combating them.
The relationship between the use of digital technologies and the provision of various types of security, namely: informational, economic, national, criminological, cyber security, etc., is investigated. In addition, the current state of the criminal situation in this area is analyzed and socio-economic factors associated with the development of digital technologies, which are actively used by criminals as a mechanism in their criminal activities, are noted. Namely, the author emphasizes that crimes committed with the use of digital technologies are practically hidden from external factors, occur remotely, which, accordingly, allows criminals to be (in another locality or even abroad) at a considerable distance from the object of the criminal offense, which considerably complicates the process of their detection, bringing guilty persons to criminal responsibility, which actualizes the indicated direction of scientific research. Also, specific proposals for improving criminal legislation in the researched area are given.