bluuebunny/crossref_metadata_2025_split huggingface dataset:
Genotoxic and Cytotoxic Effects of Belomycin and Crud Extracts of Mirabilis jalapa Linn in Male White Mice
Authors: WAGDI SABEEH SADEQ  , SHIREEN ABED AL-RAZAQ TAHA  
Published: April 2023

Genotoxicity and cytotoxicity of Belomycin (BLM) have been evaluated in bone-marroww cells by micronucleus test, as well as the analysis of sperm shape abnormalities in male white mice, considering that BLM is the most wide anticancer drug used with patients. Also, the study includes assessment the effect of crude water and alcoholic extracts of the four o'clock flowers (Mirabilis jalapa Linn) in reducing BLM toxicity and the study was carried out in the Genetics Laboratory of the Department of biology for the period from 1-10-2017 to 1-5-2019.So the genotoxicity and cytotoxicity were evaluated independently and in conjunction between two different dosages of BLM 0.8 and 1.6 mg.kg-1.bwt. and three orally dosage of different concentration of crud extracts, which is 39.8, 26.52, 13.26 mg.kg-1 and 7.02, 4.68, 2.34 mg.kg-1 o water and alcohol extract respectively.
The results of assessment of BLM genotoxic effects showed that the drug caused induction of micronuclei, here were significant increase in micronucleated polychromatic erythrocytes (MNIPCEs) and significant increase in micronuclei(MNI) in the groups treated with 0.8 and 1.6 mg.kg-1 of BLM, compare to negative control at the level of significance P <0.05
On the other hand, the results showed that BLM has potential to induce sperm shape abnormalities, which include head and tail abnormalities, It included an increase in the proportion of morphological abnormalities in the head and tail of the sperm when compared to negative control at the significant level of P <0.05.
The results also showed, that treatment with low dosages of four o'clock flower crud extracts didn’t induce neither micronuclei or any increase in PCEs numbers nor sperm shape abnormalities, although some toxic effects do exist with the higher dosages.
Evaluation of results from dependent treatments of BLM and different concentrations of water and alcoholic crud extracts, we observed significant role of these extracts in reducing toxic effects of the drug BLM in bone marrow cells, which caused significant decrease in mean differences of MNIPCEs and MNI. More over the results showed significant decrease in mean differences of sperm shape and tail abnormalities compared to negative control.
Results of the current study suggest that water and alcoholic four o'clock flower crud extracts have a role in reducing genotoxic and cytotoxic effects of BLM in bone-marrow cells and sperms of white mice
Isolation, Identification of Bacterial Species Causing Chronic suppurative Otitis Media and Detection Some of Their Virulence Factors
Authors: Yumna Shaker Mahmood  , Suha Maher Abed  , Amar Mohammed Alwan  
Published: April 2023

The study is conducted to diagnose the aerobic bacterial species causing chronic suppurative otitis media (CSOM), reveal the antibiotic susceptibility pattern and detect some of their virulence factors. Samples were collected during the period from June till December 2018. From a total of eighty-two patients admitted to Samarra Hospital and outpatient clinics of both genders with different age groups, 82 bacterial culture are recovered using a cotton swab. Identification of bacterial isolates is performed depending on micro and macroscopic cultural characteristics and biochemical tests. Results of the current work show that the highest infection rates are at the age groups >1 to 5 and 11 to 20 years by (20%). Among eight bacterial species isolated in the current study (S. aureus, P. aeruginosa, K.pneumonia, S.epidermidis, E.coli, P.vulgaris, C. freundii, E. Cloacae), S. aureus had scored the highest rate (41%) of the total infections while the lowest rate was scored by E.Cloacae(1%). The antibiotic sensitivity test suggests that almost all isolates were sensitive to ciprofloxacin and meropenem (96% and 94% respectively) while they were resistant to Cefixime. The ability of bacteria is isolated from CSOM to produce biofilm and some virulence factors (gelatinase, hemolysin, DNase, urease) are investigated the virulence factor results revealed that. S. aureus, P.aeruginosa, K. pneumonia had the ability to produce biofilm and S. aureus, P. aeruginosa have the ability the highest production for the majority of virulence factors.
Optical dispersion characterization of CZTS thin films prepared by sol gel at different annealing temperature
Authors: Ali Ismail Salih  
Published: April 2023

Thin films of (CZTS) were prepared by the sol–gel method and annealed at a range of temperatures (500, 550, 600, 650oC) under ambient condition. X-ray diffraction chart shows a preferential direction along (112) which was an indacating to the Kesterite structure. The optical properties of annealing thin films were examined by UV-Vis spectroscopy, and the energy gap was determined by the Tauc method. The band gap values increase with increasing the annealing temperature. The dispersion of refractive index of the thin film was analyzed by using the concept of single oscillator in Wemple-DiDomenico model. The average values of the dispersion energy (Ed) and the oscillator energy (Eo) of the interband optical transition were obtained, Ed≈23eV, Eo≈3.775eV and Eg≈2.15eV. The average value of the oscillator energy has a close value to that of the energy gap, for this work Eo≈1.737Eg. It has been concluded that, as the annealing temperature of the CZTS thin films increase the optical transmittance and the energy band gap will be decreased, also there is a blue shift in the shortest optical wavelength of CZTS thin films λCZTS, from 605 to 475nm with increasing annealing temperature from 500 to 600oC.
Dynamical Behavior of some families of cubic functions in complex plane
Authors: Mizal H. Alobaidi  , Omar Idan Kadham  
Published: April 2023

The current study deals with the dynamical behavior of three cubic functions in the complex plane. Critical and fixed points of all of them were studied . Properties of every point were studied and the nature of them was determined if it is either attracting or repelling. First function such that have two critical points and three fixed points such that is attracting when is origin point As shown in figure (2).And are attracting when is the region specified by open disc shown in figure (1.(c)).Second function such that have two critical points and three fixed points such that is attracting when and that its path is to the origin point as shown in figure (4).And are attractive when represents the open disc shown in the figure (3.(c)).Third function such that have one critical point and three fixed points is attracting that is path is the origin point and are repelling as shown in figure (5). And all 2-cycles of are repelling and unstable .
Certain Classes of Univalent Functions With Negative Coefficients Defined By General Linear Operator
Authors: Mazin Sh.Mahmoud  , Abdul Rahman S.Juma  , Raheam A. Mansor Al-Saphory  
Published: April 2023

In this study, a subclass of an univalent function with negative coefficients which is defined by anew general Linear operator have been introduced. The sharp results for coefficients estimators, distortion and closure bounds, Hadamard product, and Neighborhood, and this paper deals with the utilizing of many of the results for classical hypergeometric function, where there can be generalized to m-hypergeometric functions.
A subclasses of univalent functions are presented, and it has involving operator which generalizes many well-known. Denote A the class of functions f and we have other results have been studied.
Protective effect of citrus honey toward the histopathological and biochemical nephrotoxicity damages of gentamicin–induced in local rabbits Oryctolagus cuniculus
Authors: Riyam Ameen Salih  , Abdul–Karim Salim Mahood  , Samira Abdul-Hussain Abdulla  , Mohammed Abdullah Ajeel  
Published: April 2023

Drugs induced nephrotoxicity now considered as an essential reason for kidney failure. Aminoglycoside anti-infection agents, for example, gentamicin, which causes ototoxicity and nephrtotoxicity as a side effect , this research is centered around the utilization of natural materials as an antioxidants against the lethal oxidative activity that applied on the kidney cells ,the most imperative one of these materials is the honey. This work aimed to assess the defensive impact of citrus honey against the histopathological and biochemical harms of gentamicin induced nephrotoxicity .24 locally breed rabbits (Oryctolagus cuniculus) were used and divided into 4 study groups (6 rabbits per each group), group 1 received I.P daily dose of normal saline (control), group 2 received (80 mg/kg/day) I.P dose of gentamicin, group 3 received (80mg/kg/day) of gentamicin I.P dose in combination with oral dose of Citrus Honey625 mg/kg/day for 14 days and group 4 received (80mg/kg/day) of gentamicin I.P dose in combination with extra dose of Citrus Honey orally for 14 days. All animals (at 15th day) were anesthetized by ether and sacrificed; blood samples were gathered for the subsequent measurement of the serum creatinine, urea and albumin while an isolated kidney was kept in 10 % of formaldehyde for the histopathological examination. The results demonstrated that gentamicin causes nephrotoxicity showen by elevation of serum level of creatinine, urea and a decrease in the serum albumin. While the administration of honey in combination with gentamicin reduced the nephro-toxic effect of gentamicin that represented by a reduction of the serum creatinine and urea with improvement of the kidney histological findings.This study concluded that, honey decreased nephrotoxic effect of gentamicin.
Associаtіon of Еpstеіn - Bаrr vіrus іnfеctіon wіth Brеаst Cаncеr іn Kіrkuk cіty
Authors: Sаnаа Еnаm Аmееn  , Nаϳаt Аbdkаdеr Zаmаn  , Monа Sаlаh   Rаshееd  
Published: April 2023

Breast cancer is one of the most common cancers in afflicted Iraqi women. All studіеs іn recant yеаrs have іndіcatеd thаt Еpstеіn - Bаrr vіrus (ЕBV) іs аssocіatеd wіth cеrtaіn cаncеrs, іncludіng brеаst cancеr. Thе еаrly dеtеctіon of brеаst cаncеr іs thе bеst solutіon to control thе dіsеаsе. Thе purposе of thіs study іs to rеvеаl thе rеlatіonshіp bеtwееn ЕBV аnd brеаst cаncеr іn Kіrkuk cіty womеn. Thе study іncludеd thе blood sаmplіng of femаlе wіth brеаst cancеr іn thе аgеs of 23 to 88 yеars for thе pеrіod from Sеptеmbеr 2018 to Aprіl 2019. Thе total numbеr of samplеs was 100 blood samplеs for womеn wіth brеast cancеr and 10 blood samplеs of hеalthy womеn dіd not havе any dіsеasеs іn thе brеast as control to sеrologіcal analysіs was done usіng thе ЕLІSА dеvіcе to dеtеct ЕBNА-1ІgM аnd ЕВNА-1 ІgG in all sample. The results showed that (76%) of breast cancer womensample were positіvе for ЕBNА-1 ІgG While ІgM аppеаrеd nеgаtіvе in all samples, Thе hіghеst іncіdеncе of ЕВNA-1 ІgG іn female with brеаst cancеr іn thе currеnt study wаs аgеd (56 to 65) yеаrs 22% .
Conclusions: Our findings suggest that ЕBV may have а role or а rеlаtіonshіp with brеаst cancer.
Diagnostic potential of soluble TNF alpha receptor 1 in diabetic and hypertensive patients with renal impairment and UTI.
Authors: Fatin Ayoob Hameed  , Ali Mansoor Al Ameri  , Israa Hashim Saadoon  
Published: April 2023

Background: Chronic kidney disease is one of the most common diseases. Health care workers in all countries of the world are concerned with the early detection and prevention of kidney diseases. Several novel diagnostic markers are being under investigation nowadays. Tumor necrosis factor-alpha and its receptors are examples.
Aim: The present study was conducted to evaluate the role of tumor necrosis factor α receptor 1 (TNFR1) as a biomarker for detection of renal dysfunction.
Materials and Methods: The study was carried out for the period from February to June 2019 and included 180 patients (their ages were between 19 and 85 years old) and were divided into 60 patients with renal impairment, 60 hemodialysis patients, and 60 patients with normal renal function (as a control group). Each group included patients with hypertension, patients with diabetes mellitus, and hypertensive- diabetic patients.
The patients were attended to Center of Kidney Disease and Transplantation, Dialysis Unit of Baghdad Teaching Hospital – Medical City , Dialysis Unit of Tikrit Teaching Hospital and private laboratory in Samarra City.
Urine sample was collected from each patient for bacteriological study and detection the level of TNFR1.
Results: The most common pathogen isolated from cultured samples was Escherichia coli. Concentration of urinary TNFR1 in hypertensive and or diabetic with normal kidney function compared with hypertensive or and diabetic renal impairment did not differ statistically significant. Conclusion: Urinary level of tumor necrosis factor receptor 1 (TNFR1) is not important in the diagnosis of renal impairment with the presence of hypertension and or diabetes mellitus. Through statistical comparisons of patients with urinary tract infection (UTI) group and those without UTI group , it seems that UTI does not affect the diagnostic ability of urinary TNFR1. We recommend future studies focusing on serum level of the receptors mentioned above to test their diagnostic potential in renal impairment. In addition, investigating the effect of the immunological causes of renal impairment on the level of TNFR, both in urine and serum.
Synthesis and characterization of new mixed ligand complexes of Zn (II) and Hg (II) with dithiocarbamate and phosphines
Authors: Ola M. Abdul Kareem  , Hayfaa M. Jirjes  
Published: April 2023

Complexes of the type [M (Et2DTC)2]2 [M= Zn(1) or Hg(2)] were prepared from the reaction of mercury acetate or zinc acetate with sodium diethyldithiocarbamate trihydrate (NaEt2DTC.3H2O) in (1:2) molar ratio (metal: ligand) in mixture of MeOH and H2O as a solvent. Treatment equal molar of (1) or (2) with diphosphine ligands {where diphos: bis (diphenylphosphino) methane (dppm), 1,2-bis (diphenylphosphino) ethane (dppe) and 1,3-Bis (diphenylphosphino) propane (dppp)} afforded complexes of the type [Zn(Et2DTC)2(dppeO)] (3); [Zn(Et2DTC)2(dpppS)] (4a); [Zn(Et2DTC)2(dppp)] (4b); [Hg(Et2DTC)2(dppm)] (6a); [Hg(Et2DTC)2(µ-dppm)]2(6b); [Hg(Et2DTC)2(dppe)](7) and [Hg(Et2DTC)2(dppp)](8), or with two moles of triphenylphosphine (PPh3) afforded a complexes of the type [M(κ1-Et2DTC)2(PPh3)2] (5a, 9a) and [M(κ2-Et2DTC)2(PPh3)2] (5b, 9b) {M= Zn, Hg}. The prepared complexes were fully characterized by different technics such as IR, NMR (1H and 31P) spectroscopy, elemental analysis, and molar conductivity. Characterization data showed that the (Et2DTC) ligand in all of the prepared complexes was coordinated with metal through the sulfur atoms of CSS- group. The geometry of the complexes (1-9) were tetrahedral around the Zn(II) and Hg(II) ions, except isomers 5b and 9b are octahedral geometry. .
Determination of Meropenem by Spectrophotometric-Application to Pharmaceutical Preparations
Authors: Nada A. Khalil  , Walada H. Ibrahim  
Published: April 2023

A simple and sensitive spectrophotometric method was described for the determination of Meropenem in pure and in pharmaceutical formulations. 2,3 dichloro 5,6 dicyano 1,4 benzoquinone(DDQ)has been used for determination of meropenem by formation of charge transfer complex measured at 345 nm.Beer᾽s law is obeyed in the concentration range of (0.625-12.5µg/ml) The molar absorptivity (2.3889×104)l.mol1-.cm1-,Sandellʹs sensitivity index is 0.0161µg.cm2-,The method is precise (relative standard deviation RSD% is better than ±3.32%) and accurate (relative error in the range of -0.97 to-0.60%) depending on the concentration level.
The method was applied succefully to the assay of Meropenem in pharmaceutical preparation in the form of injection.
Effect of spraying of GA3 and Some Micronutrients on the growth and Mineral content of Cress plant (Lepidium sativum L.)
Authors: Jamel Y. Ali Altememe  , Noor E.M. Hachim  
Published: April 2023

This study is conducted in aspicial farm in Adujail city\Salahaddin Governorate at the season 2015 on the cress plant. Afactorial experiment has conducted with two factors, the first is spraying with GA3 (G0 without spraying, G1 spraying with 50 mg.L-1, G2 spraying with 100 mg.L-1of GA3).the second factor is spraying with Micro Nutrients (T0 without spraying, T1spraying with 50 mg.L-1 of Fe,T2 spraying with 50 mg.L-1 of Mn, T3 spraying with amixture of 50+50 mg.L-1from Fe and Mn). The experiment is designed with (RCBD), the treatments were replicated 4 times and Duncuns Multiple Range Test at the probability 5% is used and the results are as fellowed:
GA3 spraying causes asignificant increase in all Vegetative growth characters compared with the others which are not sprayed and also the Macro Nutrients concentration. Micro Nutrients sprayes on the Cress plants also causes asignificant increase in most Vegetative characters and Macro and Micro Nutrients content, specially the treatment of Fe and Mn mixture. Interaction between GA3 and Micronutrient is significant in all the treatment specially the treatment (100 mg.L-1 of GA3 + amixture of 50+50 mg.L-1 of Fe + Mn ) which give ahighest values of Vegetative growth and Macro and Micro Nutrients content .
Silver and Cobalt nanoparticles as potential antibacterial agents Staphylococcus aureus isolated from wound infections
Authors: Wisam F. Hameed1  , Yassien H. Owaid  , Bashar S. Noomi  , Aswad H. Nada  
Published: April 2023

The present study aimed to isolate and diagnose S. aureus from patients with wound infection after collecting (100) clinical samples of patients attending Salah Al-din General Hospital from the beginning of April to the end of September 2019 from different wound areas, and to study the effect of silver nanoparticles and cobalt on them. The results of the study showed that the two nanoparticles used have the ability to inhibit growth of S. aureus at different concentrations, The molecular study included the observation of the most important molecular changes at the level of DNA after treatment with nanomaterials, where many variations were observed on the bacteria studied, including these changes the emergence and disappearance of packages of DNA and different numbers when treated with nanomaterials, The results of the study showed that the laboratory rats when infected with S.aureus, appeared after about a week and the symptoms which include; clear skin scaling and hair loss at the site of infection. It is also clear that the recovery time was rapid in group of infected rats which treated with nanomaterials
New 3- hydrazonoindolin-2-one Cd(II) complexes with amino pyridine ligands, Synthesis, Characterization and biological activity evaluation
Authors: Lubna W. Mohammed  , Ahmed A. Irzoqi  
Published: April 2023

This research includes synthesis and characterization of some of Cd(II) complexes with (3-hydrazonoindolin-2-one)(HZI) ligand and amino pyridine ligands.
Treatment equialmolar of CdCl2.2.5H2O and (HZI) ligand with two moles of n-aminopyridine (n-amp) (n:2,3,4) ligands afford a tetrahedral complexes of the type [Cd(HZI)(n-amp)2]Cl2, where (HZI) ligand behaves as a bidentate chelating fashion through the N atom of azomethine group and O atom of carbonyl group. Whereas the (n-amp)(n: 2,3,4) was bonded monodentate mode through the N atom of heterocyclic ring.
The prepared complexes have been characterized by molar conductivity, elemental analysis, infrared spectra and 1H-NMR and 13C-NMR spectra.
Also the evaluation of biological activity of the prepared complexes against two types of gram positive bacteria (Staphylococcus Epidermidis and Staphylococcus aureus) and (Citrobacer Freundii) and gram negative, all prepared complexes showed activity against Staphylococcus aureus more than amikacin, while the [Cd(HZI)(3-amp)2]Cl2 complex showed high activity against Staphylococcus Epidermidis and Citrobacter freundii more than another prepared complexes
genotoxicity produced in the epithelial cells of the oral cavity and Comet assay in urinary tract of workers in aluminum factories
Authors: Sarab Dalaf Khalaf  , Wajdi Sabeeh Sadeq  
Published: April 2023

Whilst being environmentally abundant, aluminum is not essential for life. On the contrary, aluminum is a widely recognized neurotoxin that inhibits more than 200 biologically important functions and causes various adverse effects in plants, animals, and humans. The acute toxicity of aluminum is low. No acute effects due to dietary exposure to aluminum have been observed in the general population. A compendium is provided of aluminum compounds used in industrial settings, and as pharmaceuticals, food additives, cosmetics and as other household products. In our current study, the genotoxicity of aluminum was evaluated in epithelial cells by Micronucleus assay in buccal cells and Comet assay in urinary tract cells, 50 samples were taken from the workers in the aluminum factory and 50 samples as control. The results showed significant increased in the average of the affected cells (8.86 ± 1.36) and the average total cell total (51.66 ± 18.19) in urinary tract while the average of damage cells (72.02 ± 8.99) and It is noted that the mean micronuclei (1.61±29.80) and the average abnormality in all cells (3.06 ±92.54) while the Mni(51.28 ±10.61). These results suggest that the estimation of cellular genetic damage in epithelial cells by Micronucleus assay and Comet assay estimation is important to know the toxic effects of aluminum.
Comparison of prevalence of head lice Pediculus humanus capitis among male and female students of some primary schools in Tikrit City
Authors: Alaa Emad Tawfeeq  
Published: April 2023

A study was conducted to evaluate the prevalence of pediculus humanus capitis (De Geer, 1767) among male and female students of five primary schools in Tikrit (Abu Musa Al-Ash'ari for Boys and Fara'a schools for girls in Al-Shuhada neighborhood, and Hawa for girls ’school in Al-Qadisiyah / Al-Duibbat neighborhood, and a school Sincerely, first born for boys in Al-Asri neighborhood, and Madar mixed school in Shishen district).
The results showed prevalence of infection with parasite among the five school students, with a total injury rate of 21.9%, of which 13.8% for males and 80.11% for females. Consequently, the prevalence of parasite among students in 6-7 age group was higher than in rest of age groups, reaching 23.23% and lowest in 10-year age group and over, which reached 16.03%.
The study showed length and nature of hair (tribe or curly) in percentage of infection with parasite, as percentage of infection in females with short hair reached 12.14%, while weakness in females with long hair reached 23.12%, and percentage of injury among students of lower hair was 36.32% for those with Curly hair and 11.81% for tribute hair.