bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thirteen Nonpharmacological Interventions for Increasing the Quality of Life in Patients with Advanced Cancer
Authors: Tang Ying , Wang YuYang , Tian JinHui , Zhou ShuRong 
Published: February 2023

Background
A variety of nonpharmacological interventions that improve the quality of life of patients with advanced cancer have been difficult for medical staff to select through randomized controlled trials or traditional meta-analyses. Thus, a network meta-analysis is necessary.

Objective
This study used network meta-analysis to analyze the effect of 13 different nonpharmacological interventions on improving the living quality of patients with advanced cancer.

Methods
Five English databases were searched up to January 2019. The search strategy only included terms relating to or describing the intervention.

Results
The study included 13 different nonpharmacological interventions. The overall efficacy was summarized through a holistic study of quality of life. The study found that the combined effect sizes of 13 nonpharmacological interventions crossed the invalid line (weighted mean difference, −13 [95% confidence interval, −33 to 8.5] to 1.7 [95% confidence interval, −18 to 22]), indicating that none of the intervention was significantly different from each other. By evaluating the heterogeneity of this outcome, no significant evidence of heterogeneity (P > .05) was observed. Probability ranking according to the surface under the cumulative ranking curve showed that there was a great possibility for the CanWalk intervention and structured multidisciplinary intervention to improve outcomes for cancer patients.

Conclusions
Thirteen nonpharmacological interventions did not significantly impact quality of life. Regarding the probability rank, CanWalk intervention may be the most promising way that advanced cancer patients can help themselves to a better life. Because of the limitations of the current studies, the conclusion needs further evidence.

Implications for Practice
Nurses should consider recommending moderate physical activity for patients with advanced cancer.
Patient-Family Caregiver Concordance of Symptom Assessment for Esophageal Cancer Patients Undergoing Esophagectomy
Authors: Chen Yu-qing , Zhong Jiu-di , Hong Yu-tong , Yuan Juan , Zhang Jun-e 
Published: February 2023

Background
Esophageal cancer patients suffer from multiple and severe symptoms during the postoperative recovery period. Family caregivers play a vital role in assisting patients to cope with their symptoms.

Objective
To examine the concordance of esophageal cancer patients and their caregivers on assessing patients’ symptoms after surgery and identify predictors associated with the symptom concordance.

Methods
In this cross-sectional study, 213 patient-caregiver dyads completed general information questionnaires, the Memorial Symptom Assessment Scale, the Depression Subscale of Hospital Anxiety and Depression Scale, the Mutuality Scale, and the Zarit Burden Interview (for caregivers). Data were analyzed using intraclass correlation coefficients, paired t tests, and binary logistic regression.

Results
At the dyad level, agreement of patients’ and caregivers’ reported symptoms ranged from poor to fair. At the group level, patients reported significantly higher scores than caregivers in most symptoms. Of the 213 dyads, 119 (55.9%) were identified as concordant on symptom assessment. Patients’ nasogastric tube, perceived mutuality, caregivers’ educational background, and dyad’s communication frequency with each other could predict their concordance of symptom assessment.

Conclusions
There were relatively low agreements between esophageal cancer patients and caregivers on assessing patients’ symptoms, and caregivers tended to underestimate patients’ symptoms. The dyad’s symptom concordance was influenced by patient-, caregiver-, and dyad-related factors.

Implications for Practice
Having an awareness of the incongruence on assessing symptoms between esophageal cancer patients and caregivers may help healthcare professionals to comprehensively interpret patients’ symptoms and develop targeted dyadic interventions to improve their concordance, contributing to optimal symptom management and health outcomes.
Demographic Differences in Satisfaction and Work-Life Balance of Prelicensure Nursing Faculty
Authors: Crawford Ryan P. , Barbé Tammy , Randolph Justus 
Published: February 2023

Background:
A need exists to recruit and retain nursing faculty of differing generations, races/ethnicities, and genders.

Purpose:
The purpose of this study was to examine whether generational cohort, race/ethnicity, and gender predicted job satisfaction, life satisfaction, or work-life balance for full-time faculty teaching in prelicensure, baccalaureate nursing programs.

Methods:
Faculty (N = 363) from multiple schools of nursing in the United States completed a survey that included demographics, the Job Satisfaction Scale, the Satisfaction with Life Scale, and the Work-Life Balance Self-Assessment.

Results:
Significant relationships and differences were noted for nursing faculty. Faculty of color reported lower job and life satisfaction than their White counterparts.

Conclusions:
As calls to increase diversity among nursing faculty increase, continued research should focus on differences in the experience of faculty of color.
Nurse Educators' Perceptions and Self-efficacy in Response to COVID-19
Authors: Riess Dawn , Mersiovsky Amy , Gruhn Carole 
Published: February 2023

Background:
During the COVID-19 pandemic, nurse educators had to adapt quickly to required changes in nursing education following isolation mandates. Educators worked diligently to provide a quality remote/online educational experience with limited resources.

Purpose:
The purpose of this review was to explore nurse educators' perceptions and self-efficacy toward the transformation from the traditional face-to-face teaching to remote/online teaching and simulation/laboratory modifications in response to the COVID-19 pandemic.

Methods:
A scoping review, informed by PRISMA-SCR guidelines, was performed in PubMed, Web of Science, CINAHL Complete, OVID MEDLINE, and Google Scholar.

Results:
There were 34 articles included in the final review, with 7 themes identified: teaching pedagogy, technology challenges, online teaching role, learning environment, leadership, clinical education, and well-being.

Conclusions:
The review is relevant to nursing faculty across the globe. Planning for future pandemics should include self-care, use of evidence-based practices, protocols, and increased communication.
Strategies to Evaluate and Enhance Accelerated Second-Degree Nursing Pathways
Authors: Jones Kim Dupree , Hayes Rose , McCauley Linda 
Published: February 2023

Background:
Health systems are facing historic staffing crises, and they require efficient pipelines of qualified students into practice. Accelerated second-degree students are helping to address pressing health care market needs.

Problem:
Few publications have assessed the second-degree program landscape or offered comparisons of second-degree pathways.

Approach:
This article discusses the second-degree program landscape, including challenges in second-degree education; compares graduate-level second-degree entry against other pathway options; and presents strategies to optimize and sustain second-degree student pipelines based on these insights.

Findings:
The second-degree program landscape is characterized by variability. Challenges include inconsistent program nomenclature and limited national data collection. Graduate-level second-degree pathways offer financial and career advantages compared with other pathways.

Conclusion:
Nursing education should standardize second-degree nomenclature, refine national data capture mechanisms, standardize program scope and requirements, and encourage second-degree pathways at the graduate level or above.
Exploring the Use of Common Strict Search Criteria in Nursing Literature Searches
Authors: Truex Eleanor Shanklin , Spinner Emily , Hillyer Jean , Ettien A'Llyn , Wade Sarah , Calhoun Courtney , Wolf Grace , Hedreen Rebecca , Heimlich Layla , Nickum Annie , Vonderheid Susan C. 
Published: February 2023

Background:
Health sciences librarians and nursing journal contributors have expressed concern about the impact of using strict parameters when searching the literature.

Purpose:
The purpose of this study was to explore the use of strict search criteria (eg, 5-year rule, “nurse as author”) by direct care nurses and nursing students.

Methods:
Fourteen online focus groups were conducted with 54 participants: direct care nurses, health sciences librarians, nursing faculty, and nursing students. Nursing faculty and health sciences librarians were included as participants to add perspective to the origins and effects of the use of stringent search criteria.

Results:
The majority of the nurses viewed the 5-year rule and nurse as author search limits favorably, while noting that a strict date range may hamper successful searching. Librarians viewed these search criteria more unfavorably but recognized the value of topic-appropriate search limits.

Conclusion:
Reliance on strict limits can be detrimental to pertinent results; however, appropriate use is essential for relevant results. Pedagogy focused on searching the nursing literature needs to emphasize that limits are tools to be used judiciously.
Factors Associated With Willingness to Use Daily Antibiotics as Sexually Transmitted Infection Prophylaxis Among HIV Preexposure Prophylaxis–Experienced Gay and Bisexual Men in Australia
Authors: Arapali Tyson , Grulich Andrew E. , Heywood Anita E. , Chan Curtis , Fraser Doug , Zablotska Iryna B. , Holt Martin , Vaccher Stefanie J. , Bavinton Benjamin R. 
Published: February 2023

Background
Gay and bisexual men (GBM) who use HIV preexposure prophylaxis (HIV-PrEP) have high rates of bacterial sexually transmitted infections (STIs). The use of daily antibiotics as STI preexposure prophylaxis (STI-PrEP) may be appealing to GBM who are using or have previously used HIV-PrEP (HIV-PrEP–experienced) for the prevention of bacterial STIs.

Methods
We examined willingness to use daily STI-PrEP among a cross-sectional sample of HIV-PrEP–experienced GBM in Australia who participated in an observational online cohort study from August 2018 to March 2020. Factors associated with willingness to use daily STI-PrEP were determined using bivariate and multivariate logistic regression.

Results
Of the 1347 participants, half (54.3%) were willing to use daily STI-PrEP. Factors independently associated with greater willingness to use daily STI-PrEP included having >10 sexual partners in the last 6 months, using methamphetamine in the last 6 months, being more conscious about avoiding STIs, having a greater number of STIs since commencing HIV-PrEP, being willing to take HIV-PrEP for as long as they were at risk of acquiring HIV, and only using condoms when a sexual partner requested them. Conversely, factors associated with less willingness to use daily STI-PrEP included being university educated, using nondaily dosing regimens of HIV-PrEP, preferring event-driven HIV-PrEP, and being concerned about long-term HIV-PrEP adverse effects.

Conclusions
Sexually transmitted infection PrEP is likely to be appealing to many HIV-PrEP–experienced GBM, especially those who engage in activities associated with a higher risk of STI transmission. However, they are less likely to be willing to use STI-PrEP unless it aligns with their HIV-PrEP dosing regimen, suggesting that research into the safety and efficacy of alternative STI prophylaxis dosing options should be prioritized.
Testing Technologies as Enhancers of Disease Intervention Specialist Activities: Applying Lessons From COVID-19
Authors: Van Der Pol Barbara 
Published: February 2023

Abstract
Disease intervention specialists are often at the forefront of adoption of new technologies in support of sexually transmitted infection (STI) contact tracing efforts. Newer technology for detection of treatable STI includes point-of-care molecular tests for detection of chlamydia, gonorrhea, and trichomonas and syphilis serology point-of-care tests. Other additions to our case finding toolbox are the use of telemedicine and the proliferation of direct-to-consumer offerings, both of which rely on remote sample collection involving self-collection of specimens in nonclinical settings. Finally, on the near horizon are over-the-counter tests that will support self-testing without the involvement of a medical professional. Each of these new developments is discussed and contextualized in experiences resulting from the COVID-19 pandemic response. Many options are now available, or will be soon, for detection of STIs in nontraditional settings, and we need to consider the processes involved as we move toward adoption of these new tools.
HIV Testing Preferences and Characteristics of Those Who Have Never Tested for HIV in the United States
Authors: Patel Shilpa N. , Emerson Brian P. , Pitasi Marc A. , Tripp Natalie E. , Marcus Ruthanne , Delaney Kevin P. , Chavez Pollyanna R. 
Published: February 2023

Background
The initial phase of the federal Ending the HIV Epidemic in the U.S. (EHE) initiative prioritized efforts in 57 geographic areas. The US Centers for Disease Control and Prevention recommends persons aged 13 to 64 years be tested for HIV at least once as part of routine health care; however, it is unclear how effectively these testing recommendations have been implemented in EHE priority areas.

Methods
In 2021 to 2022, we analyzed data from a Web-based, nationally representative survey of adults fielded in 2021. HIV testing preferences were compared by testing history, demographic characteristics, behaviors, and geography.

Results
An estimated 72.5% of US adults had never tested for HIV. Never testing was most prevalent among those aged 18 to 29 or those 50 years or older, non-Hispanic White persons, and those living in the Midwest. Among persons living in EHE priority areas and persons reporting at least one behavior that increases risk of HIV transmission, 69.1% and 48.0%, respectively, had never tested for HIV. The top 3 HIV testing preferences among never testers were as follows: testing for HIV during a routine health care visit (41.2%), testing at an urgent care or walk-in clinic (9.6%), and self-testing (8.1%).

Conclusions
Most adults had not been tested for HIV, confirming that US Centers for Disease Control and Prevention recommendations are not being fully implemented, even in EHE priority areas. Moreover, most adults who never tested preferred testing in clinical settings, highlighting missed opportunities. As the EHE initiative continues to advance, it is critical to leverage preferred HIV testing modalities, such as routine testing in clinical settings or HIV self-testing.
The PrEP Care Continuum Among Mexican Men Who Have Sex with Men and Transwomen: a Qualitative Study
Authors: Aguilera-Mijares Santiago , Martínez-Davalos Araczy , Bautista-Arredondo Sergio , Vermandere Heleen 
Published: February 2023

ABSTRACT

Background
This article describes perceptions and experiences related to the pre-exposure prophylaxis (PrEP) care continuum of Mexican men who have sex with men (MSM) and transwomen (TW).

Methods
Between June and July 2020, we applied 24 online semi-structured interviews regarding PrEP use with 10 PrEP users, six ex-users, and eight potential users (at risk, not enrolled).

Results

Awareness: TW did not always receive the information they needed from trusted people. Acceptability: Potential users were reluctant to use PrEP due to fear of side effects, and only a few participants worried about stigma. Uptake: Potential users missed their enrollment visit and did not know how to reschedule. Adherence: Barriers included routine changes interfering with PrEP-taking habits (arriving home later, traveling, etc.) while feeling protected was reported as a facilitator. Retention: Ex-users quit PrEP services, mostly without reducing their HIV risk, because of difficulties keeping appointments and fearing long-term effects.

Conclusion
Inclusive awareness activities, tackling misbeliefs regarding side effects, and more flexible services may improve PrEP usage and enhance its impact.
Economic Evaluation of a Point-of-Care Test for Bacterial Vaginosis Among Women With Vaginal Symptoms
Authors: Jiao Boshen , Fredricks David N. , Srinivasan Sujatha , Hansen Ryan 
Published: February 2023

Background
There is an unmet need for a clinical diagnostic technology to detect bacterial vaginosis (BV) rapidly and accurately. Novel point-of-care (POC) tests have the potential to fulfill this gap. Our objective was to determine the cost-effectiveness of a hypothetical clinician-administered POC test for diagnosing BV in the United States.

Methods
We developed a state-transition microsimulation model to evaluate the cost-effectiveness of using the POC test versus usual care among women of reproductive age with vaginal symptoms. We adopted a healthcare sector perspective that included relevant healthcare costs and a societal perspective that further incorporated productivity costs. Model parameters were empirically estimated based on commercial insurance claims data or derived from published literature. The primary model outcome was incremental cost-effectiveness ratio. We started with analyzing a hypothetical POC test with a sensitivity and specificity of 0.9 and a cost of $40, followed by extensive sensitivity analyses.

Results
Using the hypothetical POC test to diagnose BV increased costs by $16 and quality-adjusted life-years by 0.0005 per person compared with the usual care, leading to an incremental cost-effectiveness ratio of $31,108 per quality-adjusted life-year gained. When also capturing the productivity costs, the POC test resulted in an average cost savings of $57. The sensitivity analyses showed that the POC test's sensitivity was more influential on its cost-effectiveness than specificity.

Conclusions
Using the POC test to diagnose BV is likely to be cost-effective relative to usual care, especially with a high sensitivity or a substantial positive effect on productivity.
Two Models for Increasing the Scope and Activities of Human Immunodeficiency Virus Partner Services Programs: Preliminary Findings From the Fast Track Project
Authors: Golub Sarit A. , Price Devon M. , Starbuck Lila , Kim Christine , Strock Leah , Misra Kavita , Mikati Tarek , Udeagu Chi-Chi 
Published: February 2023

Background
We sought to develop a novel strategy for expanding an existing human immunodeficiency virus (HIV) partner services (PS) model to provide comprehensive sexual health services, including sexually transmitted infection testing, a virtual telemedicine visit, and access to immediate start medication (antiretroviral treatment, preexposure or postexposure prophylaxis). Fast Track was a National Institutes of Health–funded implementation science trial in New York City to pilot and refine the new strategy, and examine its feasibility, acceptability, and impact.

Methods
Over the course of 1 year, health department staff collaborated with the academic research team to develop Fast Track protocols and workflows, create a cloud-based database to interview and track patients, and train disease intervention specialists to deliver the new program. The initial field-based program (Fast Track 1.0) was piloted March to December 2019. A modified telephone-based program (Fast Track 2.0) was developed in response to COVID-19 pandemic constraints and was piloted August 2020 to March 2021.

Results
These 2 pilots demonstrate the feasibility and acceptability of integrating comprehensive sexual health services into HIV PS programs. Disease intervention specialists were successfully trained to conduct comprehensive sexual health visits, and clients reported that the availability of comprehensive sexual health services made them more willing to engage with PS. Key lessons for scale-up include managing collaboration with a licensed provider, navigating technical and technological issues, and challenges in client engagement and retention.

Conclusions
The success of this integrated strategy suggests that telehealth visits may be a critical gateway to care engagement for PS clients. This model is an innovative strategy for increasing engagement with HIV testing, prevention, and treatment for underserved populations.
Multiple Organ Dysfunction and Critically Ill Children With Acute Myeloid Leukemia: Single-Center Retrospective Cohort Study
Authors: Gaugler Mary , Swinger Nathan , Rahrig April L. , Skiles Jodi , Rowan Courtney M. 
Published: February 2023

OBJECTIVES:
To describe the prevalence of multiple organ dysfunction syndrome (MODS) and critical care utilization in children and young adults with acute myeloid leukemia (AML) who have not undergone hematopoietic cell transplantation (HCT).

DESIGN:
Retrospective cohort study of MODS (defined as dysfunction of two or more organ systems) occurring any day within the first 72 hours of PICU admission.

SETTING:
Large, quaternary-care children’s hospital.

PATIENTS:
Patients 1 month through 26 years old who were treated for AML from 2011–2019.

INTERVENTIONS:
None.

MEASUREMENTS AND MAIN RESULTS:
Eighty patients with AML were included. These 80 patients had a total of 409 total non-HCT-related hospital and 71 PICU admissions. The majority 53 of 71 of PICU admissions (75%) were associated with MODS within the first 72 hours. MODS was present in 49 of 71 of PICU admissions (69%) on day 1, 29 of 52 (56%) on day 2, and 25 of 32 (78%) on day 3. The organ systems most often involved were hematologic, respiratory, and cardiovascular. There was an increasing proportion of renal failure (8/71 [11%] on day 1 to 8/32 [25%] on day 3; p = 0.02) and respiratory failure (33/71 [47%] to 24/32 [75%]; p = 0.001) as PICU stay progressed. The presence of MODS on day 1 was associated with a longer PICU length of stay (LOS) (β = 5.4 [95% CI, 0.7–10.2]; p = 0.024) and over a six-fold increased risk of an LOS over 2 days (odds ratio, 6.08 [95% CI, 1.59–23.23]; p = 0.008). Respiratory failure on admission was associated with higher risk of increased LOS.

CONCLUSIONS:
AML patients frequently require intensive care. In this cohort, MODS occurred in over half of PICU admissions and was associated with longer PICU LOS. Respiratory failure was associated with the development of MODS and progressive MODS, as well as prolonged LOS.