bluuebunny/crossref_metadata_2025_split huggingface dataset:
Green Tea and Decaffeinated Light Roasted Green Coffee Extract Combination Improved Cardiac Insulin Resistance through Free Fatty Acids and Adiponectin/FAS Pathways Amelioration in Metabolic Syndrome Rat Model
Authors: Lukitasari Mifetika , Rohman Mohammad Saifur , Nugroho Dwi Adi , Nur Kholis Mukhamad , Wahyuni Nila Aisyah , Widodo Nashi 
Published: September 2023

Background: Insulin resistance has been independently associated with cardiac diseases. Free fatty acids are recently known to induce cardiac insulin resistance due to low-grade inflammation. Therefore, the improvement of free fatty acid levels can also improve cardiac insulin resistance. This study investigated the combination of green tea and decaffeinated-light roasted green coffee extract in the improvement of free fatty acid-induced cardiac insulin resistance by improving the adiponectin/FAS pathways. Methods: This study used 25 males Sprague-Dawley rats induced by a high-fat high sucrose diet and injection of low dose streptozotocin to make a metabolic syndrome (MS) rat model and standard chow as healthy control rats. The MS rats were treated with green tea (200 mg/ b. w.), decaffeinated-light roasted green coffee (300 mg/ b. w.), and the combination of both extracts in 9 weeks. Experimental groups in this study were divided into 5 groups: 1) MS (HFHS diet + STZ) group, 2) NC (normal chow) group, 3) GT (green tea extract) group, 4) GC (decaffeinated-light roasted green coffee extract), 5) CM (combination of both extracts) group. Adiponectin and HOMA-IR level was analysed using ELISA, and the gene expression of Adipo-R1, FAS, PI3K, PDK1, Akt, GLUT4 was measured by RT-PCR. Results: The combination of green tea and decaffeinated-light roasted green coffee showed synergistic effects in improving FFA levels. The adiponectin/FAS pathways was attenuated in the CM group. Moreover, the combination also showed improvement in cardiac insulin resistance markers such as IRS1/2, PI3K, PDK1, Akt, and GLUT4. Conclusions: The combination of green tea and decaffeinated-light roasted green coffee extract improved cardiac insulin resistance better than green tea and green coffee extract administration alone by reducing free fatty acids levels through adiponectin/FAS pathways modulation.
FEATURES OF THE AUSTRIAN VARIETY OF GERMAN IN ACADEMIC DISCOURSE
Authors: Kostina Daria M. , Sidorova Elizaveta N. , Shirlina Elena N. 
Published: September 2023

The article deals with the main approaches to the study of the Austrian variant of the German language as a means of oral and written communication in the academic discourse. The authors focus on the lexical and pragmatic features of the Austrian variant of the German language that distinguish it from the language of the academic communication in Germany.
Background. Though today much attention is given to the German variants, their functioning in institutional discourse haven’t been explored enough yet, which can lead to errors in cross-lingual communication and translation.
Purpose. The aims of this paper are to analyze the main approaches and methods used in the study of the Austrian version of the German language in the academic discourse and to identify its main features on the lexical and pragmatic levels based on the results of the author’s research and the works of Austrian linguists.
Materials and methods. The methods of continuous sampling and lexicographic analysis were used to describe the lexical and pragmatic features of the written academic discourse.
Results. The paper describes the main methods for studying the Austrian variant of the German language in the academic discourse (lexicographic method, corpus analysis and sociolinguistic method) and identifies such features of the Austrian variant as terminological austriacisms, Latin words, gender-fair language, peculiarities of address and use of academic titles as well as internal multilingualism.
Practical implications. The results of the study can be used for further, deeper study of academic discourse and other institutional discourses, for further analysis of the specific features of the Austrian variant of the German language, and will also be useful for translators and participants in international academic events and academic exchange.
When did the substantial loss of child linear growth occur?
Authors: Kumala Putri Dwi Sisca , Widodo Yekti , Gunardi Hartono , Kusharisupeni  , Besral  , Djahari Abas Basuni , Syafiq Ahmad , Achadi Endang L. , Bhutta Zulfiqar A. 
Published: September 2023

Background
Epidemiological studies show that the height-for-age Z-scores (HAZ) falter dramatically shortly after birth until the end of the first two years. Understanding these changes in linear growth in the first two years can help us understand the critical period of child linear growth and propose interventions.

Objectives
This study objectives were to describe the pattern of linear growth faltering and analyze the changes in length-for-age Z-scores (LAZs) throughout the first two years based on birthweight and length status.

Methods
This study analyzed 408 children, participants in Longitudinal Study on Child Growth and Development in Bogor, Indonesia. The linear growth pattern was described based on birthweight and length status. Birthweight and length status was categorized into normal and Small for Gestational Age (SGA). Changes in LAZs (Δ LAZs) in 0–6 months, 6–12 months, and 12–23 months were calculated. General Linear Model Univariate analysis was conducted to analyze the difference of Δ LAZ between SGA and normal children.

Results
Though full-term SGA children have significantly higher linear growth velocity during the first 6 months of the infancy period, full-term SGA children could not catch up with the attained growth/height of normal children throughout the first two years. Thus, full-term SGA children ended up with a higher prevalence of stunted. Both in SGA and normal children, the substantial loss of LAZ occurred between 0–6 months.

Conclusion
The finding in this study showed that the first 1000 days of life is still the best period in stunting prevention; however, the stunting prevention program should start earlier, focusing on the first 500 days of life, and potentially the prenatal period.
Novel Raviart–Thomas Basis Functions on Anisotropic Finite Elements
Authors: Bertrand Fleurianne 
Published: September 2023

Abstract
Recently,

H
⁢

(
div
)

\mathbf{H}(\mathrm{div})

-conforming finite element families were proven to be successful on anisotropic meshes, with the help of suitable interpolation error estimates.
In order to ensure corresponding large-scale computation, this contribution provides novel Raviart–Thomas basis functions, robust regarding the anisotropy of a given triangulation.
This new set of basis functions on simplices uses a hierarchical approach, and the orientation of the basis functions is inherited from the lowest-order case.
In the higher-order case, the new basis functions can be written as a combination of the lowest-order Raviart–Thomas elements and higher-order Lagrange-elements.
This ensures robustness regarding the mesh anisotropy and assembling strategies as demonstrated in the numerical experiments.
Determination of viscosity and critical concentrations of commercial low methoxyl pectin
Authors: Purnomo Eko Hari , Nabilah Uray Ulfah , Sitanggang Azis Boing 
Published: September 2023

Abstract
Determining viscosity and critical concentrations is essential for industrial application of pectin solution. Critical concentration can be determined rheologically based on zero shear viscosity, apparent viscosity, specific viscosity, and consistency index of dilute polymer solution. Direct experimental comparison of the aforementioned methods for critical concentration determination is still lacking. Therefore, this study aims to experimentally compare different viscosity methods to determine critical concentration of three different pectin solutions (sun flower, citrus, and apple). The three pectin sources at concentrations of 0.1–3.0 % (w/v) showed Newtonian to shear thinning behavior. The critical concentration ranges of pectin, from the lowest to highest, was sunflower (0.6792−0.9589 % (w/v)), citrus (0.7172−1.0347 % (w/v)), and apple (0.7645−1.1233 % (w/v)). Critical concentration determined based on consistency index was relatively close to the result obtained from zero shear viscosity. Whereas critical concentrations of the pectin solutions determined from specific viscosity and apparent viscosity were significantly different from critical concentration determined from zero shear viscosity.
Recomposition of work and attitudes of family assistants within Covid-19 in Poland: A pilot study
Authors: Budnik Monika Anna 
Published: September 2023

Abstract
This article presents reflections on the consequence of remote work in social welfare professions in the case of family assistants. Web surveys focused on changes that came with the pandemic crisis in social welfare programs, such as family assistants. The article presents conclusions from the pilot web survey study among family assistants in June 2020 using the Survey Monkey online web survey questionnaire. Family assistants of Lower Silesia (part of the region in Poland) represent a category of professions in the social welfare system in Poland. They are employed in social welfare centers and work in the local community. The assistant has different tasks and eligibility than social workers. The family assistant knows the background of family problems, and, with them, he composes a working plan for better-functioning families. Personal contact with families before the epidemiological crisis has been replaced by remote work, replaced by changed tools, indirect contact with clients, and changing attitudes among workers. All changes have led to a transformation of daily work and organization in the workplace.
Wärmepumpen in der Fertigung
Authors: Sadjjadi-Ortlieb Bijan , Eboumbou Ebongue Yvonne , Sauer Alexander 
Published: September 2023

Abstract
Dieser Beitrag analysiert und bewertet Integrationsmöglichkeiten einer Wärmepumpe in eine bestehende Fernwärmeversorgung mit einem Fernwärme- und einem Verbraucherkreislauf. Technische Ziele der Integration der Wärmepumpe sind es, die Rücklauftemperatur der Fernwärme und den Energiebezug über die Fernwärme zu senken. Dafür wird ein dynamisches Simulationsmodell zur Bewertung der Integrationskonzepte erstellt, das im Referenzfall den Fernwärme- und den Verbraucherkreislauf sowie in den Anwendungsfällen eine zusätzliche Wärmepumpe abbildet. Durch die Einbindung der Wärmepumpe in den Produktionsprozess kann die Fernwärmebereitstellung gesenkt werden und so Primärenergie eingespart werden.
Grenzen des Working Capital Management
Authors: Bauer Daniel , Lohmann Christian 
Published: September 2023

Abstract
Die Verminderung des Working Capital erhöht unter der Ceteris-paribus-Bedingung stets den Residualgewinn. Im Rahmen einer wertorientierten Unternehmensführung besteht der Zweck des Working Capital Management in der Erhöhung des Unternehmenserfolges oder in der Verringerung von Unternehmensverlusten. Die quantitativen Grenzen des Working Capital Management werden in diesem Beitrag mithilfe eines wertorientierten Unternehmensmodells untersucht. Die Ergebnisse dienen einer realistischen Einschätzung der Erfolgswirkungen des Working Capital Management.
Pediatric ADHD Medication Errors Reported to United States Poison Centers, 2000 to 2021
Authors: DeCoster Mikaela M. , Spiller Henry A. , Badeti Jaahnavi , Casavant Marcel J. , Rine Natalie I. , Michaels Nichole L. , Zhu Motao , Smith Gary A. 
Published: September 2023

OBJECTIVES
To investigate the characteristics and trends of out-of-hospital attention-deficit/hyperactivity disorder (ADHD) medication-related therapeutic errors among youth &lt;20 years old reported to US poison centers.

METHODS
National Poison Data System data from 2000 through 2021 were analyzed. Population-based rates were calculated using US census data.

RESULTS
There were 124 383 ADHD medication-related therapeutic errors reported to US poison centers from 2000 through 2021, with the annual frequency increasing by 299.0% during that period. Two-thirds (66.6%) of the 87 691 first-ranked exposures involved children 6 to 12 years old, three-fourths (76.4%) were among males, and half (50.5%) involved amphetamines and related compounds. Most (79.7%) therapeutic errors were single-substance exposures. Although most (82.7%) individuals did not receive treatment in a health care facility (HCF), 2.3% were admitted to a HCF and 4.2% had a serious medical outcome. Children &lt;6 years old were more likely to experience a serious medical outcome (odds ratio = 2.1; 95% confidence interval: 1.9–2.3) or be admitted to a HCF (odds ratio = 3.4; 95% confidence interval: 3.0–3.7) than 6 to 19-year-olds. The most common scenarios were “inadvertently taken or given medication twice” (53.9%), followed by “inadvertently taken or given someone else’s medication” (13.4%), and “wrong medication taken or given” (12.9%).

CONCLUSIONS
The frequency of cases reported to poison centers of pediatric out-of-hospital therapeutic errors related to ADHD medications increased by almost 300% during the 22-year study period and is likely attributable to increased prescribing of these medications. Because therapeutic errors are preventable, more attention should be given to patient and caregiver education and development of improved child-resistant medication dispensing and tracking systems.
Getting psyched up: Developing the field of Sport and Exercise Psychiatry in South Africa
Authors: Burger James , Mafuze Bonginkosi 
Published: September 2023

Elite athletes and their entourage are exposed to intense stressors and commonly experience mental health symptoms and disorders. While there is limited literature on prevalence rates in a South African setting, initial data show that both current and retired athletes may experience these symptoms, but with low treatment rates. There is a need to improve mental health literacy and mental health care in athletes. Athletes may benefit from systematic mental health surveillance and additional screening during high-risk periods, such as injury or retirement. This commentary brings athlete mental health into focus and advocates for the inclusion of sport and exercise psychiatry into the athlete entourage and broader mental health team, in order to close the treatment gap. We provide seven recommendations for the initial way forward for sport and exercise psychiatry in South Africa.
Epigenetics in migraine: A review
Authors: Kumar Parvinder , Sudershan Amrit , Bharti Shikha , Sheikh Javaid Hassan , Wani Showkat Ahmad , Kumar Hardeep 
Published: September 2023

Genetic diseases are not only caused by direct mutations in "genes," but also consequences of heritable change other than mutation referred to as epigenetics and the science called epigenomics. In the present study, we aimed to review epigenetics, where we covered a quick overview of epigenetics, diseases that are caused by epigenetic modification, epigenetic as risk factors linked with migraine a cause leads to the neurodegenerative condition, and most accepted mechanisms of epigenetics. A structured research article and review of the literature was searched in the electronic databases of Google Scholar, PubMed, Springer, and Elsevier until Nov 2022 using multiple keywords. Aberrant DNA methylation pattern including hypermethylation in genes such as SLC6A5, SLC2A9, and SLC38A4, , DOCK6, COMT, GIT2, ZNF234, SOCS1. EZH2, a DNMTs enzyme is generally associated with the downregulation of gene expression but in the case of microglial, it is responsible for the upregulation of various genes including TRAF3IP2, BCL2L11, ITGAM, DAB2, NLRP12, WNT3, ADAM10. Increased expression of miRNAs such as miR-34a-5p, miR-29c-5p, miR-382-5p, miR-155, miR-126, Let-7g, hsa-miR-34a-5p, hsa-miR-375. Migraine is not only caused by non-genetic factors/ environmental factors or by brain structural alterations or genetic variations but also by alteration in epigenetics and their interaction too with other elements.
Clinical profile of longitudinally extensive transverse myelitis: A study in a tertiary care hospital in Western Rajasthan
Authors: Khichar Shubhakaran , Kaushal Nitti Kapoor , Bhargava Amit 
Published: September 2023

As there are wide differentials for longitudinally extensive transverse myelitis (LETM), its aetiology should be found to optimise therapy.Clinical profile of LETM.ambispective observational study.73 patients with acute to subacute myelitis involving 3 or more vertebral segments were properly investigated.Student t test and Mann-whitney test used, and comparison of data done using SPSS version 22.0The etiology found were in form of neuromyelitis optica spectrum disorder (NMO-SD) in 18(24.6%), para-infectious in 13(17.8%), idiopathic in 17(23.2%), infectious in 9(12.3%), and rest were acute disseminated encephalomyelitis (ADEM), subacute combined degeneration (SACD), infarct, radiation myelitis etc.It is important to find etiology of LETM to optimise the therapy as the in inflammatory myelitis other than NMOSD, the line of management differs. Relapsing nature of some myelitides is an important aspect in management
Disability, quality of life enjoyment and satisfaction of patients with bipolar affective disorder in remission
Authors: Benerji Therissa , Lella Srikanth , Kodali Madhavi , Miyan Roshan , Parvathaneni Krishna Mohan 
Published: September 2023

Bipolar affective disorders (BPAD) can lead to impaired quality of life (QOL) through intense personal suffering and disrupted familial, social and occupational functioning.Self‐report of QOL in patients with BPAD is likely to be influenced by ‘mood bias’ or cognitive distortions regarding self‐concept and functioning. Improving the QOL of patients with BPAD is one of the valued goals of treatment. This study is undertaken with the aim to evaluate quality of life and disability in patients with BPAD in remission. Patients diagnosed with BPAD, currently in remission were taken as subjects for the study. HAM-D and YMRS were applied to assess depression and mania, respectively. Fifty patients who were in remission were included and Quality of Life Enjoyment and Satisfaction Questionnaire – short form (Q-LES-Q-SF) and IDEAS were applied to evaluate quality of life and disability, respectively. Mean age of the sample was 42±3.55 years. Of the total sample, 29 (58%) were males, and 21 (42%) were females. Statistically significant association was found between number of years spent ill and quality of life (p&#60;0.05), and between number of years spent ill and disability (p&#60;0.05). Short/just significant association was also found between quality of life and disability (p&#60;0.05). No association was found between age at onset of illness and quality of life.Taken together, our results have indicated that many patients with BPAD in remission have significant disability and poorer QOL. There is a need to develop interventions to reduce the disability thereby enhancing the QOL.
Nota técnica sobre la formulación de la Estrategia Nacional de Bioeconomía en Costa Rica
Authors: Barboza Arias Luis Miguel 
Published: September 2023

El artículo describe el contexto institucional en el que se formuló la Estrategia Nacional de Bioeconomía (ENB) en Costa Rica. Se discute su potencial de articulación con las Acciones de Mitigación Nacionalmente Apropiadas (NAMAs), al considerarse que una integración adecuada de estos instrumentos puede servir a una política de desarrollo de mayor alcance. Se realiza una descripción y recopilación de información de la política pública sobre bioeconomía en Costa Rica, basada en una revisión documental. Se concluye que la ENB puede contribuir al cumplimiento de los objetivos de transición sostenible, por lo que resulta necesario la incorporación de un marco operativo que estimule la creación de nichos estratégicos de bioeconomía, en consonancia con esquemas de gobernanza y de creación de capacidades locales.
Addition of CaCO3 to culture media at the salinity of 3 g/L for freshwater tambaqui growth
Authors: Hastuti Yuni Puji , Yudistira Chandra , Nirmala Kukuh , Nurusallam Wildan , Faturochman Kurnia 
Published: September 2023

ABSTRACT Increasing of freshwater tambaqui Colossoma macropomum demand makes the farmers increase the production of the consumption fish and seed. Acceleration of the production cycle can increase total production level, and reduce the level of osmotic work can be used to improve fish growth. This study aimed to analyze the effect of the addition of calcium carbonate (CaCO3) in the saline medium of 3 g/L on the growth of freshwater tambaqui juvenile. Tambaqui used has a body length of 1.93 ± 0.1 cm and weight of 0.26 ± 0.03 g. The experiment used 15 units of aquarium at size of 30×15×25 cm3 and filled with 9 L of saline water, then added lime CaCO3 according to treatment. The treatments were control (0 mg/L CaCO3), A (50 mg/L CaCO3), B (100 mg/L CaCO3), C (150 mg/L CaCO3), and D (200 mg/L CaCO3). The study was conducted for 30 days of maintenance. Fishes were fed on bloodworms ad libitum or provided three times a day. The results showed that survival, daily growth rate, and absolute length growth of the CaCO3 treatments significantly higher (P<0.05) that that of control. Furthermore, survival, daily growth rate, and absolute length growth among the CaCO3 treatments were the same. Thus, addition CaCO3 of 50 mg/L saline water of 3 g/L can be applied to increase culture performance of freshwater tambaqui. Keywords: freshwater tambaqui, CaCO3, salinity ABSTRAK Permintaan terhadap ikan bawal air tawar Colossoma macropomum yang semakin meningkat membuat pembudidaya menambah produksi ikan konsumsi dan benih. Percepatan siklus produksi dapat meningkatkan total produksi budidaya, dan energi dari optimasi kerja osmotik dapat dialokasikan untuk pertumbuhan. Penelitian ini bertujuan untuk menganalisis pengaruh penambahan kalsium karbonat (CaCO3) pada media bersalinitas terhadap pertumbuhan benih ikan bawal air tawar. Benih ikan bawal yang digunakan memiliki panjang 1,93±0,1 cm dengan bobot 0,26±0,03 g. Akuarium yang digunakan berukuran 30×15×25 cm3 sebanyak 15 unit dan diisi air bersalinitas 3 g/L sebanyak 9 L, kemudian ditambahkan kapur CaCO3 sesuai perlakuan. Dosis setiap perlakuan terdiri atas kontrol (0 mg/L CaCO3), A (50 mg/L CaCO3), B (100 mg/L CaCO3), C (150 mg/L CaCO3), dan D (200 mg/L CaCO3). Penelitian dilakukan selama 30 hari pemeliharaan dengan pemberian pakan cacing sutra secara ad libitum atau diberikan tiga kali sehari. Hasil penelitian menunjukkan bahwa derajat kelangsungan hidup, laju pertumbuhan harian, dan panjang mutlak pada perlakuan penambahan kapur CaCO3 lebih tinggi (P<0,05) daripada kontrol. Sementara itu, derajat kelangsungan hidup, laju pertumbuhan harian, dan panjang mutlak antarperlakuan penambahan kapur CaCO3 tidak berbeda. Dengan demikian, penambahan CaCO3 sebanyak 50 mg/L air dapat diterapkan untuk perbaikan performa budidaya ikan. Kata kunci: ikan bawal air tawar, CaCO3, salinitas