bluuebunny/crossref_metadata_2025_split huggingface dataset:
Observations of convection effects on particles and heat transport in liquid metals under plasma bombardment and infrared heat radiation
Authors: Hirooka Yoshi , Bi Hailin 
Published: March 2023

Abstract
To resolve technical issues associated with the plasma-facing components (PFCs) such as divertor installed in a steady state magnetic fusion DEMO reactor, employing high-temperature metals such as tungsten for the surface component, the use of liquid metals (LMs) such as lithium has been proposed, and evaluated as a possible resolution over the past two or so decades, using plasma confinement devices as well as laboratory-scale experimental facilities.
The present work is intended to explore the effect of forced convection in liquid metals on the transport behavior of particles and heat from divertor plasma bombardment. Laboratory-scale experiments have been conducted, using GaInSn and molten lithium as the liquid metal targets to be exposed to steady state plasmas and infrared irradiation. Data clearly indicate that electromagnetically induced convection can enhance particles and heat transport in these liquid metals, proof-of-principle data for convected LM-PFCs.
A Distributed Homological based Sensor Selection and Scheduling in Wireless Sensor Networks
Authors: Varposhti Marzieh 
Published: March 2023

Abstract
One of the fundamental problems in randomly deployed sensor networks is to enhance the network lifetime along with providing full area coverage. The problem is more challenging when location information is not available. Scheduling the activities of sensor nodes in a way that each point of the area of interest is covered by at least one sensor node is a promising way when a smaller set of sensor nodes is scheduled autonomously. This autonomous sleep scheduling of sensor nodes can be efficiently done based on the topological properties of the sensor network in a distributed fashion. In this paper, we address the problem of autonomous scheduling of sensor nodes for providing full area coverage in wireless sensor networks in a distributed manner when there is no location information available. The goal is to prolong the network lifetime. The proposed method is based on homology. The idea is autonomous selection of the minimum number of active sensors with the highest level of energy based on the properties of the simplicial complex of the network. We formulate this problem as an integer programming problem. Then, we propose a distributed algorithm, which does not require the knowledge of the location of nodes or distance between them. Finally, we provide simulation results demonstrating the performance of the proposed algorithm.
Language-dependent Cue weighting in Distinctive Feature: Evidence from the Perception of Mandarin High Vowels by Native English Speakers
Authors: Zhu Wen-Hui , Lee Sun-Hee , Zhang Xin-Ting 
Published: March 2023

Abstract
This study investigates the perception of the three Mandarin high vowels /i, u, y/ after dental, retroflex and palatal fricatives and affricates /s/-/ʦ/-/ʦʰ/; /ʂ/-/tʂ/-/tʂʰ/, and /ʨ/, /ʨʰ/, /ɕ/) by native English speakers. The results of the perceptual identification and categorization experiments show that among the three target vowels, the high front rounded vowel /y/ presents the greatest challenge for native English speakers. They have a significantly higher tendency to confuse /y/ with the Mandarin high back rounded vowel /u/ compared to the Mandarin high front unrounded vowel /i/, as they perceptually classified /y/ and /u/ into the same English vowel category /u/. The findings of the study suggest that native English speakers adopt a perceptual strategy that differs from that of native Japanese and Korean speakers, relying heavier on the feature of roundness as opposed to backness in perceiving the Mandarin /y/. This study contributes to the perceptual cue weighting field by examining the weighting of phonological cues (i.e. distinctive feature) in Mandarin high vowels by native English speakers. These results hold pedagogical significance as they highlight the importance of targeted perception training for learners of different language backgrounds to enhance both their recognition and reproduction of second language sounds.
Enhanced Recovery after Surgery (ERAS) in the treatment of congenital duodenal obstruction: A single center cohort study
Authors: Treider Martin Alavi , Røkkum Henrik , Børke Wenche Bakken , Lassen Kristoffer , Bjørnland Kristin 
Published: March 2023

Abstract
Purpose:
This study aimed to investigate to what extent perioperative routines for treating neonates with congenital duodenal obstruction (CDO) aligned with the proposed Enhanced Recovery After Surgery (ERAS) recommendations for neonates and whether treatment highly corresponding with ERAS improves postoperative outcomes.
Method:
This is a cohort study of neonates undergoing surgery for CDO at Oslo University Hospital (2009-2020). Data were reviewed in 2022 and compared with the ERAS recommendations; high correspondence was defined as treatment corresponding with >70% of the recommendations.
Results:
Of 69 included neonates with CDO, 19 (28%) received treatment highly corresponding with the ERAS recommendations, and the overall median correspondence rate was 62.5 (14-88) %. Forty-two (65%) neonates received opioid treatment postoperatively; median total morphine equivalents were 0.1 mg/kg. Neonates in the high correspondence group received fewer morphine equivalents (p=0.027), but no significant differences were seen in terms of postoperative length of stay and complication rate. The overall correspondence with ERAS recommendations increased during the study period (p<0.001).
Conclusion:
Many of the ERAS recommendations have been a part of the treatment of neonates with CDO during the last decade. Neonates with treatment highly corresponding to ERAS recommendation received less opioid treatment than neonates with low correspondence.
Changing temperature trends at subtropical mountains in southeastern China
Authors: Qin Yihui , Wei Yuxing , Lu Jiayi , Mao Jiahui , Deng Haijun , Chen Xingwei , Gao Lu , Chen Ying , Liu Meibing 
Published: March 2023

Abstract
In the context of global warming, mountain warming has significantly elevation-dependent. Currently, most studies focusing on high-altitude mountainous areas lack examples of middle and low-altitude mountainous areas. Southeastern China's Fujian Province has the Wuyi Mountains in the northwest and coastal plains in the southeast, making it an ideal place to study temperature warming change with elevation. Therefore, based on 64 meteorological stations' daily observation data in Fujian Province from 1961 to 2018, the Mann-Kendall nonparametric test method was used to analyze the spatial-temporal patterns of temperatures and their elevation-dependent warming characteristics. The results show that (1) Fujian Province has experienced significant warming from 1961 to 2018, where the mean temperature is 0.20°C/decade, the maximum temperature is 0.17°C/decade, and the minimum temperature is 0.26°C/decade. The mean, maximum, and minimum temperatures abruptly changed around 1997, 2000, and 1998, respectively. (2) In 1961-1990, more than 63% of stations experienced a decline in annual mean temperature, mainly because the maximum temperature decreased during this period, whereas for 1971-2000, 1981-2010, and 1991-2018, the maximum, minimum and mean temperatures have been increasing. (3) In Fujian Province, there are significant spatial differences in temperature variations, with the maximum warming trend of mean temperature occurring in the southeast coastal plains, the maximum warming trend of maximum temperature occurring in the northwestern mountainous region, and the minimum temperature is warming faster in the southeast coast and northwestern mountains than in the central region. (4) In the study area, no elevation-dependent warming of mean, maximum, and minimum temperatures was observed, indicating that middle and low-altitude mountainous regions of the subtropics do not experience elevation-dependent warming of temperatures.
Construction of Invariant Relations of $n$ Symmetric Second-Order Tensors
Authors: Aguiar Adair Roberto , Rocha Gabriel Lopes da 
Published: March 2023

Abstract
methodology is presented to find either implicit or explicit relations between invariants in a minimal integrity basis for n symmetric secondorder tensors defined on a three-dimensional euclidean space. The implicit relations are called syzygies. The methodology i) allows the construction of a set of 6 n−3 independent invariants, ii) yields explicit non-polynomial expressions for certain invariants in terms of the remaining invariants in the integrity basis, and iii) allows the construction of syzygies. The results of this investigation are important in modeling biological structures, which, in general, are non-homogeneous and made of anisotropic viscoelastic materials that are subjected to large deformations and are modeled through constitutive relations that depend on symmetric tensors.
The Intervention of oil constituents from Garcinia kola against epidermal growth factor receptor in breast cancer using in-silico analysis
Authors: Folayan A. D. , Akintunde J. K. , Akamo A. J. , Oyelakin A. S 
Published: March 2023

Abstract
The most common form of cancer among women worldwide and the leading cause of cancer death among black women is breast cancer (BC). Important biological targets in the therapy of cancer, epidermal growth factor receptors (EGFR) have been found to be substantially expressed in cases of triple-negative breast cancer (TNBC). Thus, drugs that focus on this receptor may reduce the incidence of breast cancer. This study, therefore, aims at investigating the inhibitory potential of oil constituents from Garcinia kola against epidermal growth factor receptors in breast cancer using in-silico approaches. Human EGFR structure was obtained from Maestro module version 11.8. Docking of Garcinia kola oil constituents against human EGFR was done using Auto/Vina in Pymol 4.2 while physicochemical and pharmacokinetic parameters were assessed using Qikprop. Phytochemical analysis was carried out with GC-MS. This study revealed the presence of twenty phytocompounds in Garcinia kola oil. Docking of isolated compounds against EGFR showed that 1,2-Benzenediol, 3,5- bis (1,1-dimethyl ethyl)- and Phyto acetate had the best docking scores of -7.309 and -6.326 respectively. Many of the components of Garcinia kola oil may be eligible as oral medications because they met the criteria for drug-likeness while still being within allowable limits. A significant portion of the chemicals in Garcinia kola oil may act as novel EGFR inhibitors and may be a potent anti-breast cancer drug, according to in-silico data from molecular docking scores, binding free energy, projected pIC50 values, and ADMET evaluation. To confirm the oil components of Garcinia kola as an anticancer agent, however, more research is needed.
Photocatalytic Properties of Molybdenum Oxide Photoelectrode Synthesized by Spray Pyrolysis Method
Authors: Jubu Peverga R. , Yusuf Bashir , Yusof Y. , McAsule A. A. , Aondoakaa S. I. , Tsaviv N. J. , Chahul H. F. , Shiada M. S. , Gundu A. A. , Erukaa M. 
Published: March 2023

Abstract
The present work reports the photocatalytic properties of pyrolyzed molybdenum oxide thin film. Microstructural analysis reveals clustered nanoaggregates. Structural analysis shows polycrystalline 𝛼-MoO3 phase. The crystallite size, dislocation density, microstrain and stacking faults are found to be 41.27 nm, 5.87 ×10−4 lines/cm2, 8.41 ×10−4 and 1.78, respectively. The optical bandgap is found to be 3.20 eV. Linear sweep voltammetry measurement in 1 M KOH electrolyte reveal significant photocurrent density of 992.39 𝜇A/cm2 at bias of 1 V vs. Ag/AgCl. The reasonable performance of the device suggest that the spray pyrolysis method is promising for preparing photosensitive MoO3 films for photoelectrochemical measurement.
Occipital artery-posterior inferior cerebellar artery bypass: a cadaveric feasibility study
Authors: Yuan Yong , Wang Xiaolong , Han Li , Tuo Yuanzhao , Wu Bomeng , Ding Xinmin 
Published: March 2023

Abstract
Pupose: To demonstrate that the occipital artery(OA)-p1 posterior inferior cerebellar artery(PICA) bypass can be an alternative for complex posterior circulation aneurysms.
Methods: A far-lateral approach to craniotomy was performed on 10 adult head and neck specimens(a total of 20 sides occipital artery), and the OA was obtained 'in-line.' Its length, diameter, and the number of p1/p2 and p3 segmental perforators were determined, and the relationship between caudal loop and cerebellar tonsil position was also assessed. The distance between the PICA’s origin and the cranial nerve XI (CN XI), the buffer length above the CN XI after dissection, the OA length required to complete the OA-p1/p3 PICA bypass, and the p1 and p3 segment diameters were all measured.
Results: All specimens underwent OA-p1 PICA end-to-end bypass, 15 sides underwent OA-p3 PICA end-to-side bypass, and the other bypass protocols were less common. The buffer length above the CN XI after dissection, the distance between the PICA’s origin and the CN XI, and the first perforator were all of sufficient length. The direct length of the OA needed to complete the OA-p1 PICA end-to-end bypass was significantly less than the available length and the OA-p3 PICA end-to-side bypass, with the OA matching the p1 segment diameter. The number of p1 perforators was less than that of p3, and the OA diameter was equal to that of the p1 segment.
Conclusion: OA-p1 PICA end-to-end bypass is a feasible alternative in cases which p3 segment has high caudal loops or anatomic anomalies.
An Optimization Method For Pruning Rates of Each Layer in CNN Based on the GA-SMSM
Authors: Dong Xiaoyu , Li Binqi , Song Yuantao 
Published: March 2023

Abstract
Parameter pruning is one of the main methods for compressing CNN models. It can reduce the redundant parameters, the complexity of time and space, and calculation resources of the network while ensuring the minimal loss of the network's performance. Currently, most existing parameter pruning methods have equal pruning rates in all layers. Unlike previous methods, this paper focuses on the optimal combination of each layer’s pruning rates for a given pruning rate of the whole model. First, we use the genetic algorithm to obtain the pruning rate for each layer, where the pruning rate for each layer is not necessarily the same, but the average of the pruning rates is no more than the given pruning rate. Then, we order the similarity of filters to determine the pruning objects, using the sum of matrix similarity based on cosine similarity. We use VGGNet and ResNet for experimental validation on CIFAR10 and ImageNet ILSVRC2012.The results show that the accuracy loss of the pruned model using GA-SMSM is lower than that of previous methods.
Functional Outcomes of Hirschsprung's Disease in Children - A Single Center Study Done at The Children's Hospital Lahore
Authors: Saleem Muhammad , Butt Jamaal , Shoukat Zubair , Hashim Imran , Muhammad Moeezah , Majeed Fatima , Saleem Umer , Kamran Muhammad 
Published: March 2023

Abstract
Aim: Hirschsprung’s Disease (HD) is a congenital bowel disorder resulting in functional dysmotility. Advancement in surgical techniques has improved outcomes but recent studies have identified problems having significant impact on patient's quality of life. The aim of this study is to analyze post-operative functional outcome after definitive surgery for Hirschsprung’s disease.
Method:A retrospective study was conducted in the department of Pediatric Surgery, The Children's Hospital Lahore. The record of 64 patients was reviewed from the year 2009 - 2019. Parents were interviewed on phone calls and a predesigned questionnaire was filled. Degree of constipation, incontinence and voluntary bowel movements was analyzed according to Krickenbeck Classification.
Results: Median age at initial presentation was 11 days, with male to female ratio of 3.9:1. Most common presentation was delayed passage of meconium (38%). Diagnosis was made on biopsy in 70.3%, while contrast enema and biopsy in 29.7 %. Aganglionosis was limited to short segment in 81.3% & long segment in 14.5%. Decompressing enterostomy was made in 63% at mean age of 191 days. Definitive surgery included Duhamel pull through in 89.1%. The mean age at follow up was 10.6±4.19 years and alive patients are 95.4%. Post-operative enterocolitis was reported by 27%, while 35.5% reported fecal incontinence and 16.1% had complained of constipation. For voluntary bowel movements, 80% could hold bowel movement, among which 5% with feeling of urge and 15% had the capacity to verbalize. In 25 % of patients, fecal incontinence was a constant social problem and in 25% of these patients, constipation was resistant to diet and laxatives.
Conclusion: On long term follow up; fecal incontinence was more worrisome affecting quality of life requiring help of bowel management program. Such patients need close follow up after definitive procedure, so that they have normal stooling habits in their adulthood and lead a normal life.
Volume Fractional Change of Nano-Particle for Enhanced Localization Probability in Surface Plasmon Polariton Dispersion Relation at AgSiO2-Cesium Atomic Interface
Authors: khan Zakir , Bilal Muhammad , Khan Majid , Khan Aizaz , Bacha B. A. 
Published: March 2023

Abstract
This manuscript investigates atomic microscopy at the interface ofa silver silica $AgSiO_2$ nano-composite and cesium atomic mediumusing surface plasmon polariton dispersion relation. The studyreveals the measurement of sharp localization peaks on both thereal and imaginary parts of the dispersion relation of SPPs. Asharp single localization peak is reported in sub-half wave lengthdomain having minimum uncertainty in position with high precisionprobability. The study also reveals double, triple, four, and evenfive localized peaks in one wavelength domain with the highintensity of control field. The localization probability at theimaginary part ranges from $30-35\%$, while the real part rangesfrom $96-98\%$ on the dispersion relation of SPPs. Thesignificance of this work is that the localization probability isenhanced with the volume fractional change of the nano-particlewithout disturbing the position uncertainty.
Phase I study of repeated peripheral infusions of anti-EGFRvIII CAR T cells in combination with pembrolizumab in patients with newly diagnosed, MGMT-unmethylated glioblastoma
Authors: Bagley Stephen J. , Binder Zev A. , Desai Arati S. , Nasrallah Maclean P. , Maloney Eileen , Brem Steven , Lustig Robert , Kurtz Goldie , Alonso-Basanta Michelle , Mohan Suyash , Hwang Wei-Ting , Tang Oliver Y. , Logun Meghan , Bhattacharyya Meghna , Markowitz Kelly , Delman Devora , Marshall Amy , Alanio Cecile , Beatty Gregory L. , Brogdon Jennifer L. , Hexner Elizabeth , O'Rourke Donald M. 
Published: March 2023

Abstract
Treatment efficacy with chimeric antigen receptor (CAR) T cell therapy in glioblastoma (GBM) is undermined by an immunosuppressive tumor microenvironment (TME). We previously showed that CAR T cell therapy targeting epidermal growth factor receptor variant III (EGFRvIII) produces anti-tumor activity against recurrent GBM and causes upregulation of programmed death-ligand 1 (PD-L1) in the TME. Here, we conducted a phase I trial to study the impact of CART-EGFRvIII cells administered concomitantly with the PD-1 inhibitor pembrolizumab in patients (n = 7) with newly diagnosed, EGFRvIII + GBM. Treatment was well tolerated without incidence of dose-limiting toxicity. However, no signal of efficacy was detected with a median progression-free survival of 5.2 months (90% CI, 2.9–6.0 months) and median overall survival of 11.8 months (90% CI, 9.2–14.2 months). In addition, PD-1 expression in the CART-EGFRvIII infusion product did not correlate with outcomes, and peripheral CAR T cell engraftment was relatively short-lived. Together, these findings show the safety of combining CAR T cells and PD-1 inhibition in GBM but given the lack of efficacy, also indicate a need to consider alternative combinatorial strategies. ClinicalTrials.gov registration: NCT03726515.
Relativistic Particle Measurements in Jupiter’s Magnetosphere with Pix.PAN
Authors: Hulsman Johannes , Wu Xin , Azzarello Philipp , Bergmann Benedikt , Campbell Michael , Clark George , Cadoux Franck , Ilzawa Tomoya , Kollmann Peter , Llopart Xavier , Nénon Quentin , Paniccia Mercedes , Roussos Elias , Smolyanskiy Petr , Sukhonos Daniil , Thonet Pierre Alexandre 
Published: March 2023

Abstract
Pix.PAN is a compact cylindrical magnetic spectrometer, intended to provide excellent high energy particle measurements under high rate and hostile operating conditions in space. Its principal design is composed of 2 Halbach-array magnetic sectors and 6 Timepix4-based tracking layers; the latest hybrid silicon pixel detector readout ASIC designed. Due to Pix.PAN's compact and relatively simple design, it has the potential to be used for space missions exploring with measurements of unprecedented precision, high energy particles in radiation belts and the heliophere (solar energetic particles, anomalous and galactic cosmic rays). In this white paper, we discuss the design and expected performance of Pix.PAN for COMPASS (Comprehensive Observations of Magnetospheric Particle Acceleration, Sources, and Sinks), a mission concept submitted to NASA’s Call "B.16 Heliophysics Mission Concept Studies (HMCS)" in 2021 that targets the extreme high energy particle environment of Jupiter's inner radiation belts. We also discuss PixPAN's operational conditions and interface requirements. The conceptual design shows that is possible to achieve an energy resolution of <12% for electrons in the range of 10MeV-1GeV and <35% for protons between ~200MeV to a few GeV. Due to the timestamp precision of Timepix4, a time resolution (on an instrument level) of about 100ps can be achieved for time-of-flight measurements. In the most intense radiation environments of the COMPASS mission, Pix.PAN is expected to have a maximum hit rate of 44MHz/cm2 which is below the design limit of 360MHz/cm2 of Timepix4. Finally, a sensor design is proposed which allows the instrument to operate with a power budget of 20W without the loss of scientific performance.