bluuebunny/crossref_metadata_2025_split huggingface dataset:
Handwashing among caregivers of young children in a protracted and complex refugee and immigration context: a mixed methods study on the Thai–Myanmar border
Authors: Pooseesod Kasama , Umezaki Masahiro , Phetrak Athit , Phuanukoonnon Suparat 
Published: July 2023

IntroductionProtracted refugee situations create complex contexts that present significant health risks for young children. Effective hand hygiene practices by caregivers can reduce respiratory infections and diarrhoeal disease, the two largest contributors to mortality among children between 1 month and 5 years of age. This study documented handwashing patterns and access to water, sanitation and hygiene (WASH) infrastructure among caregivers of young children living along the Thai–Myanmar border, one of the world’s most protracted and complex refugee and immigration contexts. It also examined the association between handwashing and socio-demographic variables and captured participants’ explanations for when and how hands are washed. The study broadened the scope of previous research by also including the large number of caregivers living outside formal camps.MethodsCaregivers of children attending 11 preschools in Tak province, Thailand participated in a mixed-methods cross-sectional study. Quantitative questionnaire data (n = 384) were supplemented by a thematic analysis of data from in-depth interviews (n = 9).ResultsFewer than half the caregivers reported routinely washing their hands before preparing meals or after using the latrine/toilet. Fewer than one-in-five routinely used soap in these situations. Interviewees explained that handwashing was only necessary when a substance could be felt or seen, in which case wiping with a cloth or a rinsing with water were sufficient to clean hands. However, their explanations also suggested some potential avenues for culturally appropriate and feasible interventions to improve hand hygiene.ConclusionThe results confirmed previous research on the multi-dimensional barriers to good hand hygiene in protracted refugee situations and other low-resource settings. Additional investment to overcome shortages in the infrastructure necessary to support good hand hygiene and creative means of drawing on and developing human capital will be necessary to realize the potential hand hygiene holds for reducing ill-health and mortality among young children living in these contexts.
COVID-19 or threat of a nuclear war in Europe? A cross-sectional study of anxiety levels in adults living in Portugal
Authors: Prazeres Filipe , Maricoto Tiago , Lima Inês Sampaio , Simões Pedro , Simões José Augusto 
Published: July 2023

BackgroundSince 2019, Europe has experienced ongoing stressors with the emergence of the COVID-19 pandemic and the Russian–Ukrainian War, which have had social, financial, physical, and psychological impacts. Studies suggest that anxiety, fear, post-traumatic stress disorder, depression, and other psychological disorders are common in such situations, and there is a need for more research on the impact of the war on mental health in Portugal. The main goal of the present study was to assess the impact of the fear of COVID-19 and anxiety related to nuclear war on the general anxiety levels of adult individuals living in Portugal.MethodsA cross-sectional study was conducted from May to July 2022 using an online questionnaire built on the Google Forms platform. Portuguese-speaking male and female individuals aged 18 years or older, who provided informed consent and agreed to participate, were included. The outcome variable was defined using the Portuguese version of the GAD-7 scale, while the main predictors were the FCV-19S and the NWA Scale in Portuguese. Linear and logistic regression models were used to test associations between predictors and outcome variable.ResultsThe study included 1,182 participants, with a mean age of 46.5 (±11.7) years, mostly women (80.6%). The global mean GAD-7 score was 5.8 (±4.5) points, and 17.9% of the participants scored above the 10-point cutoff. Higher scores were found in both the FCV-19S and the NWA scale among participants with anxiety, as measured by both a 10-point cutoff (p &lt; 0.001), and GAD-7 scale mean scores (p &lt; 0.001). The study showed that fear of COVID-19 [OR of 1.133 (95%CI: 1.097–1.170)] and, at a lesser extent, nuclear war anxiety [OR of 1.020 (95%CI, 1.009–1.031)] contribute to anxiety in the general population. This is also true for those with a personal history of anxiety, revealed by multiple regression.DiscussionThis study contributes to the research on COVID-19’s impact on anxiety and provides the first comprehensive assessment of nuclear war anxiety in Portugal. Results highlight the need for long-term care for anxiety, as prevalence is expected to increase due to the pandemic and war, even in non-conflict areas like Portugal.
Stakeholders’ views and experiences on implementing new diagnostics in primary care to support management of community-acquired acute respiratory tract infections: a qualitative study
Authors: Hoste Melanie Eugenie , Colman Elien , Wanat Marta , Hayward Gail , Tissier Jean-Louis , Postma Maarten , Goossens Herman , Anthierens Sibyl , Tonkin-Crine Sarah ,   on behalf of the VALUE-Dx study team
Published: July 2023

BackgroundThe majority of antibiotics are prescribed in primary care for respiratory tract infections. Point-of-care tests (POCTs) for the management of community-acquired acute respiratory tract infections (CA-ARTI) have been developed to help optimize antibiotic prescribing. While some countries in Europe have adopted these tests in primary care settings, most have not. Stakeholders, such as policy-makers, regulators, the diagnostic industry, and scientific associations, have roles in the implementation of new diagnostics in primary care. The aim of this study is to explore these stakeholders’ views and experiences, and identify areas of unmet need relating to POCT implementation.MethodsStakeholders were recruited using purposive sampling and snowballing. Between March 2021 and May 2022, semi-structured interviews were conducted online with stakeholders in Belgium, the UK and from European Union (EU) -level organizations. Interviews were audio recorded and transcribed verbatim. Transcripts were analysed inductively and deductively using thematic analysis.ResultsTwenty-six stakeholders participated: eleven from EU-level organizations, seven from Belgium, and eight from the UK. Five themes were identified. Stakeholders felt a balance of top-down and bottom-up approaches were an optimal strategy to the implementation of POCTs. Stakeholders stressed the need to engage with clinicians to act as champions for tests to help raise awareness and generate new evidence on how tests are used. While acknowledging the potential of POCTs for improving patient outcomes and impacting antibiotic prescribing behavior, some raised concerns on how tests would be used in practice and wished to see national data on effectiveness. COVID-19 catalyzed the use of tests, but stakeholders were pessimistic that processes for approving diagnostics during the pandemic would be replicated in the future.ConclusionStakeholders provided recommendations for research and practice. Robust reimbursement policies could alleviate financial burden from clinicians and patients, encouraging practices to adopt POCTs. Industry is likely to benefit from engaging as early on as possible with other stakeholders. Due to uncertainty among stakeholders on the impact of POCTs on antibiotic prescribing, further evidence is needed to understand how practices adopt POCTs and the implications for stewardship. Monitoring how POCTs are used can inform future guidelines on successful diagnostic implementation.
The international platform of registered systematic review and meta-analysis protocols (INPLASY) at 3 years: an analysis of 4,658 registered protocols on inplasy.com, platform features, and website statistics
Authors: Canellas João Vitor dos Santos , Ritto Fabio Gamboa , Rodolico Alessandro , Aguglia Eugenio , Fernandes Gustavo Vicentis de Oliveira , Figueredo Carlos Marcelo da Silva , Vettore Mario Vianna 
Published: July 2023

BackgroundINPLASY® is an international platform for registering systematic reviews and meta-analysis protocols that was launched in March 2020. INPLASY® provides an online database in which the protocols are maintained as permanent public records and can be accessed on its website (www.inplasy.com).MethodsWe described the database features and registered information of all records published since the launch of the registry on March 31, 2023. Additionally, we analyzed the website statistics dataset to explore user experience and promote data transparency.ResultsFour thousand six hundred fifty-eight records were registered in INPLASY®, and more than 94% of the protocols were published within 24 h. Most of the submissions were from China, followed by Portugal, Taiwan, Malaysia, and Brazil. The INPLASY® website received 386,395 page views from 64,568 visitors during the first three years. The accesses were obtained from 170 countries. Most of the accesses were from China, followed by the US, the UK, and Portugal. The review status “completed and published” was observed in 898 protocols, and these studies were published in 372 different scientific peer-reviewed journals. The features of INPLASY® include the following: (i) INPLASY® identifier, a unique protocol number; (ii) the digital object identifier (DOI) number, the URL of the protocol linked to a specific DOI; (iii) ORCID update, INPLASY® automatically updates authors' ORCID page, including their protocol; and (iv) search tools, the protocols are freely accessible on www.inplasy.com.ConclusionsINPLASY® has several practical and useful features that should be considered when planning the registration of a systematic review protocol. Furthermore, the sharp increase in the number of protocols registered in INPLASY® in the first three years and the database statistics demonstrate that INPLASY® has become an important source of systematic review protocols. Therefore, authors should access INPLASY® before planning a future review study to avoid unintended duplication of efforts and to obtain timely registration.
The Antibacterial Effect of the Films Coated with the Layers Based on Uncaria tomentosa and Formitopsis betulina Extracts and ZnO Nanoparticles and Their Influence on the Secondary Shelf-Life of Sliced Cooked Ham
Authors: Ordon Magdalena , Burdajewicz Weronika , Sternal Józef , Okręglicki Marcin , Mizielińska Małgorzata 
Published: July 2023

Microbial surface contamination of the cooked ham sliced by shop assistants has an influence on its potential secondary shelf-life. Active packaging may be the solution. The first goal of the work was to obtain coatings based on Formitopsis betulina and Uncaria tomentosa extracts (separately), with the addition of nanoparticles of ZnO (as a synergetic agent to increase plant extracts’ antimicrobial effectiveness), that could be active against selected bacterial strains. Another aim of the work was to determine the influence of obtained active layers on microbial purity and texture of the samples. The results of the study demonstrated that the layers containing F. betulina or U. tomentosa extracts with the addition of ZnO nanoparticles inhibited Staphylococcus aureus, Bacillus atrophaeus, and Escherichia coli growth completely and decreased the number of Pseudomonas syringae cells. Analyzing microbial purity of sliced cooked ham portions after storage, it was observed that the active packaging based on U. tomentosa extracts had a greater influence on the total count than the coatings containing F. betulina extracts and that both active packaging materials affected the microbial purity of the cooked ham. Analyzing the textural parameter changes after 48 h of storage, a decrease in the gumminess, chewiness and cohesiveness values was noted, but only for the ham portions stored in bags covered with the coating based on U. tomentosa. The effectiveness of the active packaging on textural parameters after 96 h of storage was not noticed.
Adsorption of Sc on the Surface of Kaolinite (001): A Density Functional Theory Study
Authors: Zhao Zilong , Wang Kaiyu , Wu Guoyuan , Jiang Dengbang , Lan Yaozhong 
Published: July 2023

The adsorption behavior of Sc on the surface of kaolinite (001) was investigated using the density functional theory via the generalized gradient approximation plane-wave pseudopotential method. The highest coordination numbers of hydrated Sc3+, ScOH2+, and ScOH2 + species are eight, six, and five, respectively. The adsorption model was based on ScOH2H2O5+, which has the most stable ionic configuration in the liquid phase. According to the adsorption energy and bonding mechanism, the adsorption of Sc ionic species can be categorized into outer layer and inner layer adsorptions. We found that the hydrated Sc ions were mainly adsorbed on the outer layer of the kaolinite (001)Al-OH and (00−1)Si-O surfaces through hydrogen bonding while also being adsorbed on the inner layer of the deprotonated kaolinite (001)Al-OH surface through coordination bonding. The inner layer adsorption has three adsorption configurations, with the lying hydroxyl group (Ol) position having the lowest adsorption energy (−653.32 KJ/mol). The adsorption energy for the inner layer is lower compared to the outer layer, while the extent of deprotonation is limited. This is because the deprotonation of the inner adsorption layer is energetically unfavorable. We speculate that Sc ions species predominantly adsorb onto the surface of kaolinite (001) in an outer layer configuration.
Hydrogen-Assisted Microdamage of Eutectoid Pearlitic Steel in the Presence of Notches: The Tearing Topography Surface
Authors: Toribio Jesús 
Published: July 2023

This paper studies the hydrogen-assisted microdamage (HAMD) in fully-pearlitic steel. A detailed analysis is provided of the HAMD region in axisymmetric round-notched samples of high-strength eutectoid pearlitic steel under hydrogen embrittlement environmental conditions. The microscopic appearance and evolution of the hydrogen affected region is analyzed from the initiation (sub-critical) to the fracture (critical) situations. The use of very distinct notched samples and their associated stress distributions in the vicinity of the notch tip allows for a study of the key role of the triaxial stress state on hydrogen diffusion and micro-cracking (or micro-damage). The microscopic appearance of the hydrogen-affected zone (the so-called tearing topography surface) resembles micro-damage, micro-cracking or micro-tearing at a micro- or nano-scale due to hydrogen degradation, thus affecting the notch tensile strength and producing hydrogen embrittlement. A micromechanical model is proposed to explain these hydrogen effects on the material on the basis of the lamellar micro- and nano-structure of the pearlitic steel.
Camellia oleifera CoSWEET10 Is Crucial for Seed Development and Drought Resistance by Mediating Sugar Transport in Transgenic Arabidopsis
Authors: Ye Zhihua , Du Bingshuai , Zhou Jing , Cao Yibo , Zhang Lingyun 
Published: July 2023

Sugar transport from the source leaf to the sink organ is critical for seed development and crop yield, as well as for responding to abiotic stress. SWEETs (sugar will eventually be exported transporters) mediate sugar efflux into the reproductive sink and are therefore considered key candidate proteins for sugar unloading during seed development. However, the specific mechanism underlying the sugar unloading to seeds in Camellia oleifera remains elusive. Here, we identified a SWEET gene named CoSWEET10, which belongs to Clade III and has high expression levels in the seeds of C. oleifera. CoSWEET10 is a plasma membrane-localized protein. The complementation assay of CoSWEET10 in SUSY7/ura3 and EBY.VW4000 yeast strains showed that CoSWEET10 has the ability to transport sucrose, glucose, and fructose. Through the C. oleifera seeds in vitro culture, we found that the expression of CoSWEET10 can be induced by hexose and sucrose, and especially glucose. By generating the restoration lines of CoSWEET10 in Arabidopsis atsweet10, we found that CoSWEET10 restored the seed defect phenotype of the mutant by regulating soluble sugar accumulation and increased plant drought tolerance. Collectively, our study demonstrates that CoSWEET10 plays a dual role in promoting seed development and enhancing plant drought resistance as a sucrose and hexose transporter.
Evaluación de sílabos por competencias del programa de estudios de enfermería en una universidad pública, Perú
Authors: Herrera García Yamira Iraisa , Gutiérrez de Carrillo Carmen Inés , Ojeda Pérez José Miguel , Maizondo Saldaña Ferrer Robinson , Medina Yera Elena del Carmen , Tejada Muñoz Sonia 
Published: July 2023

Objetivo: Esta investigación se realizó con el objetivo de evaluar en dos momentos los elementos estructurales del sílabo con enfoque de competencias y la articulación con el perfil de egreso del programa de estudios de Enfermería de la Universidad Nacional Toribio Rodríguez de Mendoza de Amazonas, 2021. Método: La metodología usada fue de enfoque cuantitativo, técnica de revisión documental, diseño observacional, comparativo y transversal. La muestra estuvo representada por 42 sílabos. El instrumento fue una lista de cotejo, con una validez adecuada (VC=4.7>de VT=1.64). Para el procesamiento de datos se utilizó el paquete estadístico IBM SPSS v.25 y para el análisis, la prueba estadística no paramétrica de WILCOXON con 95% de confianza y 0.05 margen de error. Resultados principales: Los resultados fueron; en el primer momento el 69.00% de los sílabos no cumplían con los requisitos de revisión de los elementos: información general, sumilla, competencias genéricas, competencias del curso, criterios de evaluación, programación de contenidos, indicadores y evaluación de los aprendizajes, estrategias de enseñanza–aprendizaje, asistencia e inhabilitación, recursos educativos, evaluación y comunicación de los resultados, instrumentos de evaluación y referencias bibliográficas y el 31.00% de los silabos evidenciarion los elementos; sin embargo, en el segundo momento el 95.20% de los sílabos cumplieron con los requisitos estimados y descritos para la revisión. Conclusión general: Concluyéndose que el segundo momento de la evaluación de los sílabos difiere de manera significativa del primero, debido al acompañamiento pedagógico sistematizado del equipo multidisciplinario en la formación académica de enfermería.
Formulasi Dan Penetapan Nilai SPF Sediaan Losion Tabir Surya Mengandung Ekstrak Daun Jambu Biji Berdaging Putih (Psidium guajava L.) Secara In Vitro
Authors: Amsiyah Seftinur , Mardiyanti Siti 
Published: July 2023

Latar Belakang : Salah satu tanaman yang memiliki potensi sebagai tabir surya adalah tanaman jambu biji. Daun jambu biji berdaging buah putih (Psidium guajava L.) mengandung senyawa metabolit sekunder seperti flavonoid kuersetin. Tujuan: Penelitian ini bertujuan untuk memformulasikan dan menentukan nilai SPF sediaan losion dari ekstrak daun jambu biji berdaging putih. Metode: Ekstraksi, Fraksinasi, Uji nilai SPF, Evaluasi karakteristik fisik losion, Uji stabilitas dengan cycling test. Hasil: Hasil pengujian SPF secara in vitro dari ekstrak etil asetat daun jambu biji berdaging putih (Psidium guajava L.) pada konsentrasi 250 ppm adalah 15,17 dengan kategori proteksi ultra. Nilai SPF sediaan losion yang mengandung ekstrak daun jambu biji berdaging putih dengan konsentrasi 1,25% pada formula 1, formula 2, dan formula 3, berturut-turut yaitu 13.33; 13.32; 13.29. Hasil evaluasi losion tabir surya yaitu berwarna hijau muda, bau lemah, homogen, pH 6, tipe emulsi m/a, dan daya sebar 5,025-6,075 cm. Uji stabilitas dengan cycling test menunjukkan hasil bahwa ketiga fomula sediaan losion tabir surya mengandung daun jambu biji berdaging putih stabil. Kesimpulan: Dari hasil tersebut dapat disimpulkan bahwa sediaan losion tabir surya yang dibuat memiliki efektivitas sebagai tabir surya dengan karakteristik fisik dan stabilitas yang baik.
Kata kunci: daun jambu biji, losion, tabir surya, SPF, stabilitas.
Analisis Kesalahan Siswa Dalam Menyelesaikan Soal Cerita SPLTV Ditinjau Dari Motivasi Belajar
Authors: Nopiana Rida , Ratnaningsih Nani 
Published: July 2023

Soal cerita matematika sangat penting dipahami oleh siswa, karena soal cerita matematika berkaitan dengan kehidupan. Namun, masih banyak siswa yang kesulitan dalam menyelesaikan soal cerita matematika. Tingkat motivasi belajar yang berbeda-beda, dapat mempengaruhi kesalahan siswa dalam menyelesaikan soal cerita matematika. Penelitian ini menggunakan metode deskriptif kualitatif. Subjek penelitian ini adalah 18 siswa kelas XI IPS 3 MAN 5 Tasikmalaya dan dipilih 3 subjek dengan pemilihan secara purposive dengan pertimbangan hasil skor angket dari masing-masing kategori dan banyaknya kesalahan. Hasil dari penelitian ini, subjek dengan kategori motivasi tinggi hanya melakukan 2 kesalahan hanya pada jenis kesalahan memahami (Comprehension Error), yaitu tidak menuliskan apa yang diketahui dan tidak menuliskan apa yang ditanyakan dalam soal. Subjek dengan kategori motivasi sedang melakukan 5 kesalahan pada jenis kesalahan memahami (Comprehension Error), kesalahan keterampilan (Process Skill Error), dan kesalahan penulisan akhir (Enconding Error), yaitu tidak menuliskan apa yang diketahui, tidak menuliskan apa yang ditanyakan, tidak menuliskan permisalan, salah dalam melakukan perhitungan, dan salah dalam menuliskan kesimpulan akhir. Sedangkan pada subjek dengan kategori motivasi rendah melakukan 7 kesalahan pada semua jenis kesalahan, yaitu tidak menuliskan apa yang diketahui, tidak menuliskan apa yang ditanyakan, tidak menuliskan permisalan, salah menyusun persamaan dari soal, tidak melanjutkan proses penyelesaian, salah dalam melakukan perhitungan, dan tidak menuliskan kesimpulan akhir. Untuk peneliti selanjutnya disarankan melakukan wawancara kepada subjek penelitian untuk mendapatkan informasi yang lebih mendalam
Analisis Kondisi Psikologis Siswa Dalam Pembelajaran Matematika Melalui Asesmen Diagnostik
Authors: Hidayat Yandi Wahyu , Maharani Anggita 
Published: July 2023

Penelitian ini bertujuan untuk mengetahui kondisi psikologi siswa dalam pembelajaran matematika. Kondisi psikologi siswa penting untuk diketahui sebagai pedoman dalam menyusun perencanaan pembelajaran. Penelitian ini merupakan penelitian deskriptif dengan pendekatan kuantitatif. Penelitian ini mengdeskripsikan hasil analisis psikologi siswa SMA Negeri 1 Beber yang meliputi: emosi, keyakinan diri, minat, dan motivasi. Subjek penelitian ini sebanyak 30 siswa SMA Kelas XII IPS SMA Negeri 1 Beber. Berdasarkan analisis hasil angket psikologi dapat disimpulkan bahwa kesiapan siswa dalam belajar matematika dari aspek psikologi mencapai angka 66% atau masuk kategori sedang. Penerapan belajar kelompok pada proses belajar matematika dapat dijadikan pilihan oleh guru untuk dapat meningkatkan minat siswa dalam belajar. Pemberian tugas berbasis projek dapat diberikan untuk mengurangi kebosanan siswa dalam mengerjakan soal-soal matematika dan untuk menambah pengalaman siswa dalam proses pembelajaran.