bluuebunny/crossref_metadata_2025_split huggingface dataset:
Single-Stage Posterior Vomerine Ostectomy and Primary Cheiloplasty in Patients with Bilateral Cleft Lip & Palate and Protuberant Premaxilla
Authors: Hamdan Usama S. , Younan Robert A. , Haddad Mario , Melhem Antonio M. , Najjar Wassim , Hussein Sara , Kantar Rami S. , Annan Beyhan , Johnson Adam , Liau James 
Published: May 2023

Objective A protruded premaxilla has always been challenging to care for by cleft care professionals. This study aims to fortify the use of a single-stage premaxillary setback, with posterior vomerine ostectomy and primary cheiloplasty to achieve proper care for patients with bilateral cleft lip and palate (BCLP) and protruded premaxilla. Design Longitudinal retrospective analysis. Setting Twenty-three outreach programs to four countries (Ecuador, Lebanon, Peru, and El-Salvador) between 2016-2022. Patients/Participants Sixty-five patients between the ages of 3 months and 6 years and 5 months, with BCLP and severely protruded premaxilla underwent premaxillary setback via posterior vomerine ostectomy and primary cheiloplasty. Patients with diagnosed syndromes and inaccessible vomer bone due to fused palates were excluded from the study. Interventions Premaxillary setback with posterior vomerine ostectomy, bilateral gingivoperiosteoplasties (GPP), and primary cheiloplasty. Main Outcome Measure(s) Postoperative complications and aesthetic outcomes. Results The mean age at surgery was 13.17 ± 14.1 months, with an average follow-up time of 26 ± 17 months. Patients underwent their procedures in Ecuador (72%), Peru (9%), Lebanon (8%) and El-Salvador (1%). The majority of patients were aged 1 year or less (66.7%) and were males (58.5%). All patients were operated on successfully and had good aesthetic outcomes. Only one patient developed partial necrosis. Conclusion Patients with BCLP and severe premaxillary protrusion have always carried immense social, psychological, and financial burdens, especially in outreach settings. Our described single-stage technique has proven to be safe and effective with good aesthetic results. Further follow-up after primary repair should be done to document and ensure proper facial growth and normal nasolabial maturation.
An unusual case of checkpoint-inhibitor-induced pleuropericarditis
Authors: Suarez Zoilo K , Finke Ana C , Hospedales Emilio , Perez Ernesto , Sharifzadeh Arya , Foster Jennifer , Ferris Allison 
Published: May 2023

Introduction Pembrolizumab is an immune checkpoint inhibitor that promotes effector T-cell functions on malignant cells by binding to programmed cell death protein 1 (PD-1). Pembrolizumab is well tolerated in most cases with an adverse event profile consisting mainly of pruritus, fatigue, and anorexia. Cardiotoxicity comprises 1% of the total adverse events. Case report We present a case of a 64-year-old female with non-small cell lung cancer (NSCLC) who developed pleuropericarditis following pembrolizumab therapy. Management & outcome The patient was successfully managed with colchicine, furosemide, and timely initiation of methylprednisolone with the improvement of her symptoms. The decision to discontinue pembrolizumab was made, and six months after this intervention, the patient has remained asymptomatic. Discussion Clinicians should recognize these potential immune-mediated adverse effects to provide effective and timely management and optimize patient care.
Correlation Between Attention Deficit Hyperactivity Disorder, Internet Gaming Disorder or Gaming Disorder
Authors: Hong Ji Sun , Bae Sujin , Starcervic Vladan , Han Doug Hyun 
Published: May 2023

Objective: Individuals with internet gaming disorder (IGD) or gaming disorder (GD) had a higher prevalence of ADHD than individuals without IGD or GD. The overpathologizing of excessive gaming behaviors may be associated with the functional impairment due to ADHD in individuals with GD. Methods: The present study was designed to compare the gaming patterns, accompanying psychopathology, and co-occurring psychiatric disorders, especially ADHD, between clinical and general gamer samples (17–29 years old). Results: Out of the nine IGD criteria, the item “functional impairment” had low diagnostic accuracy in participants with IGD or GD. The IGD (GD) group had a higher prevalence of ADHD compared to the general gamer group. Conversely, there was a higher prevalence of IGD (GD) in the ADHD group compared to the non-ADHD group. Discussion: The possibility of ADHD should be considered when IGD or GD is diagnosed in patients with problematic Internet gaming.
The Injuries of Competitive Irish Dancers
Authors: McGuinness Donna , Doody Catherine 
Published: May 2023

Objectives The purpose of this study was to determine the rate and types of injury in competitive dancers of Irish Dance, establish the injury prevention measures used by dancers, and investigate any relationships between prevention measures and incidence of injury. There are no in depth published studies on injury rates or injury prevention strategies for Irish dance. Methods One hundred and fifty nine Irish dancers who were participants at the North American Irish Dance Championships (July 2-7, 2004) took part in this descriptive epidemiology study. Each participant completed a self administered questionnaire. The subjects were aged from 15 to 24 years (mean: 17.8; SD: 2.9). The number of years dancing ranged from 1 to 20 years (mean: 10.8; SD: 3.8). Results The results showed 79% (n = 125) of dancers had one or more injuries. The ankle (31%, n = 60) and foot (25%, n = 48) were the most frequently injured. Sixty-three percent (n = 121) of the dancers took over 21 days to recover from their injuries. Use of shock absorbent dance shoes significantly reduced the incidence of ankle injury (p < 0.0001). In addition warm up and cool down were associated with a decreased incidence of ankle injury (p < 0.0001 and p < 0.0001 respectively). Conclusions A variety of lower limb and in particular ankle injuries was reported by the competitive Irish dancers in this study. Injury prevention methods for ankle injury such as warm up, cool down, and use of shock absorbing dance shoes were associated with a decreased incidence of injury and warrant further investigation.
Assessment of the Knowledge, Prevalence, and Control Strategies of Malaria Among Households in Sunyani Municipality, Bono Region, Ghana
Authors: Agyemang-Badu Samuel Yaw , Awuah Esi , Oduro-Kwarteng Sampson , Dzamesi Justice Yao Woelinam , Azure Simon Agongo 
Published: May 2023

Background: Malaria remains a global public health concern for centuries. The study assessed the knowledge, prevalence and control strategies of malaria among households in the Sunyani Municipality, Bono Region, Ghana. Method: A simple random sampling method was used to administer semi-structured questionnaires to the respondents (n = 422). STATA version 14.0 was used to analyse the data and the results were presented in charts, graphs, and tables. Result: The study shows that the knowledge level of malaria, its vector of transmission and mosquitoes breeding sites among the respondents was quite high. Among the respondents, 43% reported to have been infected by malaria once in a year and 94% indicated that, their relatives have been infected with malaria parasites previously. Also, majority, 65% of the respondents selected environmental management and sanitation (EMS), followed by settlement (building houses) away from wetlands, 20.0% as alternative vector control methods to be employed to supplement the core vector control methods in the Municipality. Further, majority, 69% of the respondents indicated that enforcement of environmental sanitation bye-laws will compel residents to clean their environment, and this is likely to eliminate most mosquito breeding sites, whiles 46% called on Government to support, and employ more Environmental Health Officers and Sanitary Labourers, and adequately resource them to work effectively. Conclusion: Health authorities in the Sunyani Municipality must intensified education on malaria at all levels with the aim to influence the attitudes of households towards its prevention and control. Central and Local Government must employ more Environmental Health Officers, and empower and adequately resourced them to strictly enforce the environmental sanitation bye-laws. Malaria control authorities in the study area must consider employing environmental management and sanitation (EMS) and application of larvicides for mosquito larval control as alternative/supplementary malaria prevention and control methods to compliments the current core vector control methods.
Fabrication of multifunctional cotton textile with battery waste- derived graphene oxide for enhanced joule heating and electromagnetic interference shielding
Authors: Suryaprabha Thirumalaisamy , Park Seungkyung 
Published: May 2023

Nowadays, the research on wearable electronics have received tremendous attraction because of their potential applications in personalized health monitoring and treatment, energy conversion and storage, and human-machine interface system. Herein, we report a facile route for the fabrication of electrically conductive cotton fabric with excellent joule heating and high electromagnetic shielding performances using graphene oxide (GO) and silver nitrate (AgNO3). The GO used in this study is exclusively synthesized from spent batteries in order to minimize the environmental pollution. The surface morphology, elemental analysis, electrical conductivity, thermo-heating behavior and electromagnetic shielding performance have been studied systematically. Due to the high electrical conductivity, the GO-Ag coated cotton with 5 wt% of GO reached high surface temperature of 117.8°C within 35 s, and also it exhibits high electromagnetic interference shielding efficiency value of 79.08 dB. The high flexibility, excellent conductivity, electromagnetic shielding efficiency and joule heating performance of GO-Ag coated cotton fabric suggesting that the GO synthesized from spent batteries will be a potential and valuable resource for the new generation of wearable electronics.
Activation of neurons and satellite glial cells in the DRG produces morphine-induced hyperalgesia
Authors: Yamakita Shunsuke , Fujita Daisuke , Sudo Kazuki , Ishikawa Daiki , Kushimoto Kohsuke , Horii Yasuhiko , Amaya Fumimasa 
Published: May 2023

Activation of neurons and glial cells in the dorsal root ganglion is one of the key mechanisms for the development of hyperalgesia. The aim of the present study was to examine the role of neuroglial activity in the development of opioid-induced hyperalgesia. Male rats were treated with morphine daily for 3 days. The resultant phosphorylation of extracellular signal-regulated kinase (ERK) 1/2 in the dorsal root ganglion was analyzed by immunohistochemistry and Western blotting. Pain hypersensitivity was analyzed using behavioral studies. The amount of cytokine expression in the dorsal root ganglion was also analyzed. Repeated morphine treatment induced hyperalgesia and marked induction of phosphorylated ERK1/2 in the neurons and satellite glial cells on day 3. An opioid receptor antagonist, toll like receptor-4 inhibitor, MAP/ERK kinase (MEK) inhibitor and gap junction inhibitor inhibited morphine-induced hyperalgesia and ERK1/2 phosphorylation. Morphine treatment induced alteration of cytokine expression, which was inhibited by the opioid receptor antagonist, toll like receptor-4 inhibitor, MEK inhibitor and gap junction inhibitor. Dexamethasone inhibited morphine-induced hyperalgesia and ERK1/2 phosphorylation after morphine treatment. The peripherally restricted opioid receptor antagonist, methylnaltrexone, inhibited hyperalgesia and ERK1/2 phosphorylation. Morphine activates ERK1/2 in neurons and satellite glial cells in the dorsal root ganglion via the opioid receptor and toll like receptor-4. ERK1/2 phosphorylation is gap junction-dependent and is associated with the alteration of cytokine expression. Inhibition of neuroinflammation by activation of neurons and glia might be a promising target to prevent opioid-induced hyperalgesia.
The landscape of biomedical research progress, challenges and prospects in Saudi Arabia-A systematic review
Authors: Uddin Mohy , Alharbi Naif Khalaf 
Published: May 2023

Introduction The main objective of this review was to synthesize the progress, challenges and prospects of biomedical research in Saudi Arabia in order to provide a holistic view to all stakeholders, such as policy makers, decision makers, and local researchers along with external collaborators interested in the field of biomedical research in this region. Methods A systematic review was conducted using the scientific literature for bibliometric studies in the field of biomedical research in Saudi Arabia that comprehensively covered past few decades using PubMed. The search was performed by combining verified Medical Subject Heading (MeSH) terms: “biomedical research”, “bibliometrics”, “Saudi Arabia” using boolean operator “AND”. The data collection was done from January to June 2022 by both authors. Results Out of 202 articles yielded from initial search, 13 articles met all of the inclusion criteria and were examined in details. The outcome of analysis showed that with the augmentation of Research and Development (R&D) globalization in Saudi Arabia, researchers are publishing internationally and collaborating globally, academic and research centers are enriching research environment and policies, and government is taking many initiatives to bolster biomedical research; but still more improvements needs to be achieved by Saudi Arabia to be in the list of strong competitive leading nations in the global biomedical research field. Conclusions There were various key challenges related to biomedical publications and bibliometric aspects for Saudi Arabia that included: publishing preferences, quality of publications, indexing services, international scientific community, and importantly barriers related to planning, funding, training, resources and support at institutional and national levels. This review provided some insights and recommendations to enhance biomedical research in Saudi Arabia that included: effective policies, health priorities, building infrastructures, greater investments, high incentives, skilled recruitment, competitive training and engagement of community that can play a vital role in this context.
Individual and Organizational Factors Associated With Breastfeeding Practices in Employed Mothers
Authors: Ray Robin 
Published: May 2023

Background: Breastfeeding is recommended for infants through 6 months of age, when solid foods are introduced, and continued until 12 months of age. However, many mothers in the United States discontinue breastfeeding at an early age and return to work following childbirth. The purpose of this study was to identify individual and organizational factors associated with breastfeeding practices in a sample of employed mothers who participated in the Infant Feeding Practices Study II. Methods: A secondary analysis was conducted on a sample of 953 employed mothers who completed the Infant Feeding Practices Study II between 2005 and 2007. The analysis compares infant feeding status (breastfeeding/feeding pumped milk vs. not breastfeeding/feeding pumped milk) over a 12-month period, using generalized linear mixed modeling (GLMM). Findings: Generalized linear mixed modeling (GLMM) revealed that working mothers who were employed part-time (≤34 hours/week) were 97% more likely to continue breastfeed compared with mothers employed full-time over the 12-month follow-up period ( OR = 1.97, p = .002). Mothers who perceived high levels of breastfeeding support in the workplace were 178% more likely to continue breastfeeding compared with those with low levels of perceived support ( OR = 2.78, p < .001). Conclusions: Prenatal breastfeeding only feeding intentions, non-smoking, part-time employment, and higher levels of perceived breastfeeding support in the workplace were significant predictors of breastfeeding/feeding pumped milk at all time points. Application to Practice: Occupational health nurses may be able to address barriers to breastfeeding in the workplace and improve supportive workplace practices to promote continued breastfeeding in employed mothers consistent with national and international recommendations.
The Femoral Nerve Block Setting the Agenda for Nursing Care of Older Patients With hip Fractures—A Qualitative Study
Authors: Unneby Anna , Olofsson Birgitta , Lindgren Britt-Marie 
Published: May 2023

Introduction Hip fractures among older people are common worldwide, and it is often associated with preoperative pain. Due to increased comorbidity and high age, traditional pain relief can be a challenge. An alternative to traditional pain relief is a femoral nerve block, which is safe and suitable for anesthesia and analgesia for hip fractures among patients with or without dementia. It is essential to provide adequate pain management, and nurses report negative attitudes toward opioids and seem to prefer alternative pain management. To our knowledge, no study has focused on staff's experiences of nursing care for patients treated with femoral nerve block. Aim To describe staff's experiences providing nursing care in preoperative pain and pain management to older patients with a hip fracture who received a femoral nerve block. Design A qualitative exploratory design. Method Semistructured interviews with 19 nurses or assistant nurses in an orthopedic ward or emergency department. They were experienced in caring for patients with hip fractures who received treatment with a femoral nerve block. The interviews were subjected to qualitative content analysis. Results Staff described the femoral nerve block as setting the agenda when caring for older patients with hip fractures in the preoperative phase. The outcome of the femoral nerve block affected nursing care, depending on if the femoral nerve block was successful or not. Nursing care requires timing, with a need for staff orienting to time and customizing their communication. Further, staff faced ethical challenges regarding doing good and not harm, relieving pain, and avoiding side effects. Conclusions The femoral nerve block was an important issue for nursing staff in patients with hip fractures in the preoperative phase. Our results point toward the benefits of giving femoral nerve blocks as soon as possible to facilitate nursing care, however, this should be studied in future research.
Alternative Clinical Practice During the COVID-19 Pandemic: A Qualitative Study of Nursing Students’ Potential Loss of Experience
Authors: Malones Bente Dale , Susanne Melbye Marita Christina , Eines Trude Fløystad , Alteren Johanne 
Published: May 2023

Introduction During the COVID-19 pandemic, the lockdown of nursing institutions changed nursing students’ learning conditions in clinical practice. They were removed from their ordinary clinical practice and isolated in their homes for one week before resuming an alternative clinical practice. Owing to the changed learning conditions, nursing students had to readjust and find new and different solutions to manage their own learning. Objectives This study aimed to investigate the impact of removing first-year nursing students from clinical practice during the COVID-19 pandemic on their perceived learning and development. Methods A qualitative descriptive and interpretative design based on group and individual interviews was used. Eleven first-year nursing students from a university college in Norway participated in the study. They were interviewed from their homes, after completing their first 10-week clinical practice. Three group interviews and two individual interviews were recorded using the digital live video aid Zoom and analyzed using systematic text condensation. Results The main theme “loss of experience,” summarized how the nursing students experienced their first clinical practice during the COVID-19 lockdown. The nursing students shifted from a predictable to an unpredictable clinical practice without supervision from the nurse supervisor or the nurse educator. The organization and planning of the practice were left to the students, who bore the responsibility of achieving the learning outcomes. Three categories were identified: unpredictable learning situations, compensating learning activities, and achieving learning outcomes. Conclusions Nursing students faced difficulties in their first clinical practice during the COVID-19 lockdown, which made a challenging study situation. Too much autonomy and responsibility for their own learning reinforced a loss of experience. The uncertainty of the study situation potentially harmed their professional development, learning outcomes, and self-efficacy, especially concerning basic nursing skills.
The Effect of Family-Centered and Peer-Centered Education on the Sleep Quality of Hemodialysis Patients: A Randomized Clinical Trial
Authors: Mardanpour Maryam , Rezaei Jahangir , Vaisi Raygani Ali Akbar , Abdi Alireza , Salari Nader , Khaledi-Paveh Behnam , Mohammadi Mohammad Mehdi 
Published: May 2023

Introduction Sleep disorders in hemodialysis patients are of high prevalence affecting the lives of these patients. Objective The present study was conducted to investigate the effect of family-centered and peer-centered education on the sleep quality of hemodialysis patients. Methods In this controlled clinical trial, 90 patients were randomly assigned to three groups (control, family-centered, and peer-centered). All three groups completed Pittsburgh Sleep Quality Index before the intervention. The intervention included five training sessions conducted by the researcher according to the patients’ needs to improve their sleep quality. Routine ward interventions were performed for the control group. At the end of the study, the Pittsburgh Sleep Quality Index was completed by all three groups once again. Data were collected and analyzed using SPSS version 24 software and statistical tests. Results No significant difference was found between the two intervention and control groups regarding demographic variables and variables related to sleep quality before the intervention ( p < .05). However, based on the results of the Wilcoxon test, there was a statistically significant difference between the mean rank of sleep quality in the intervention and control groups after the intervention ( p-value = .008), indicating that sleep hygiene education was effective in the two intervention groups. Conclusion According to the findings, the mean rank of sleep quality in the two intervention groups was significant after the training, indicating the effectiveness of family-centered and peer-centered education. Accordingly, medical healthcare managers, policymakers, and planners, including nurses, are recommended to employ these convenient, safe, and cost-free training methods and provide better sleep quality and more comfort to patients by spending a short period of time for training.