bluuebunny/crossref_metadata_2025_split huggingface dataset:
Disagreement between mothers' and fathers' rating of health-related quality of life in children with cancer
Authors: Meryk Andreas , Kropshofer Gabriele , Hetzer Benjamin , Riedl David , Lehmann Jens , Rumpold Gerhard , Haid Alexandra , Schneeberger-Carta Verena , Salvador Christina , Rabensteiner Evelyn , Rothmund Maria-Sophie , Holzner Bernhard , Crazzolara Roman 
Published: January 2023

AbstractPurposeSerial assessment of health condition based on self-report made by children and their proxies has consistently shown a lack of congruence. The study explored the discrepancies between mother’s, father’s, and children’s reports on health-related quality of life (HRQOL) during the first two months of pediatric cancer treatment.MethodsIn this cohort study, children and parents completed the generic and cancer-specific Pediatric Quality-of-Life Inventory (PedsQL) questionnaires at initial diagnosis and in the subsequent months. Evaluation of discrepancies included intraclass correlations between mother–child and father–child dyads at different domain levels.ResultsThirty-six children with a diagnosis of cancer between May 2020 and November 2021 and their parents were included in this study. At diagnosis, mother–child dyads showed better agreement on more domains of the PedsQL Generic Core Scale than father–child dyads; moderate agreement persisted for both parents at subsequent time points on the physical domain. The disease-specific PedsQL Cancer Module revealed moderate and better agreement for mother–child dyads during active cancer therapy. In particular, agreement of mother–child dyads was pronounced for domains such as worry (0.77 [95% CI 0.52–0.89,P < 0.001]), whereas fathers tended to overestimate the child’s symptom burden for most of the remaining domains of the PedsQL Cancer Module.ConclusionThis cohort study shows that both parent proxy reports can provide valid information on child’s HRQOL, but that fathers tend to overestimate, particularly for non-observable domains. Proxy reports derived from mothers more closely agreed with children’s HRQOL and might be more weighted, if there is uncertainty between parents.
Meta-analytic connectivity modelling of functional magnetic resonance imaging studies in autism spectrum disorders
Authors: Goodwill Alicia M. , Low Li Tong , Fox Peter T. , Fox P. Mickle , Poon Kenneth K. , Bhowmick Sourav S. , Chen S. H. Annabel 
Published: January 2023

AbstractSocial and non-social deficits in autism spectrum disorders (ASD) persist into adulthood and may share common regions of aberrant neural activations. The current meta-analysis investigated activation differences between ASD and neurotypical controls irrespective of task type. Activation likelihood estimation meta-analyses were performed to examine consistent hypo-activated and/or hyper-activated regions for all tasks combined, and for social and non-social tasks separately; meta-analytic connectivity modelling and behavioral/paradigm analyses were performed to examine co-activated regions and associated behaviors. One hundred studies (mean age range = 18–41 years) were included. For all tasks combined, the ASD group showed significant (p < .05) hypo-activation in one cluster around the left amygdala (peak − 26, -2, -20, volume = 1336 mm3, maximum ALE = 0.0327), and this cluster co-activated with two other clusters around the right cerebellum (peak 42, -56, -22, volume = 2560mm3, maximum ALE = 0.049) Lobule VI/Crus I and the left fusiform gyrus (BA47) (peak − 42, -46, -18, volume = 1616 mm3, maximum ALE = 0.046) and left cerebellum (peak − 42, -58, -20, volume = 1616mm3, maximum ALE = 0.033) Lobule VI/Crus I. While the left amygdala was associated with negative emotion (fear) (z = 3.047), the left fusiform gyrus/cerebellum Lobule VI/Crus I cluster was associated with language semantics (z = 3.724) and action observation (z = 3.077). These findings highlight the left amygdala as a region consistently hypo-activated in ASD and suggest the potential involvement of fusiform gyrus and cerebellum in social cognition in ASD. Future research should further elucidate if and how amygdala-fusiform/cerebellar connectivity relates to social and non-social cognition in adults with ASD.
Effects of edible chitosan coating containing Salvia rosmarinus essential oil on quality characteristics and shelf life extension of rabbit meat during chilled storage
Authors: El Bayomi Rasha M. , Shata Rania H. M. , Mahmoud Abdallah Fikry A. 
Published: January 2023

AbstractRabbit meat is one of the most consumed meats throughout the world and is extremely susceptible to spoilage due to its high protein and moisture content. Natural preservatives with antioxidant and antibacterial properties are needed to maintain meat quality and increase its shelf life. This study examined the effect of 1% chitosan (CH), 0.2% rosemary (Salvia rosmarinus) essential oil (REO), and their combination on pH, total volatile basic nitrogen (TVB-N) and thiobarbituric acid (TBA) levels, and the microbial profile of rabbit meat stored over 12 days at 4 °C. During this time, changes in appearance, odor, and texture were also noted. The shelf lives of samples treated with only 1% CH coating, or in combination with 0.2% REO, were longer than those of untreated samples. These results showed that samples treated with both CH and REO were still acceptable until the 12th day and resulted in significantly lower meat demerit scores in these treated groups compared with untreated meat. In all groups, the pH, TVB-N, and TBA values increased over time, but these values were significantly higher (p < 0.05) in untreated samples. Microbial analysis results showed that chilled rabbit meat samples treated with combined 1% CH and 0.2% REO reduced Enterobacteriaceae, Pseudomonas, and Psychrotrophic counts. The experimental results demonstrated that using CH coating in combination with REO improved the quality of rabbit meat and could be an effective approach to reduce rabbit meat deterioration during chilled storage.
Spectrofluorimetric assay of amlodipine and perindopril in their raw materials, pharmaceutical formulations and spiked human plasma through the formation of complexes with Eosin Y
Authors: Salem Hesham , Abdelaziz Amany , Derayea Sayed , Nagy Dalia M. , El-Din Khalid M. Badr 
Published: January 2023

AbstractFor quantitation of amlodipine (AML) and perindopril (PER) in their authentic, pharmaceutical formulations and spiked human plasma, a simple, sensitive, validated and inexpensive spectrofluorimetric method has been developed. The proposed method is developed to be based on quantitative quenching effect of two antihypertensive drugs on Eosin Y's native fluorescence which was achieved by developing binary complexes between each of the cited drugs in an acidic environment using acetate buffer (pH 4.4) with Eosin Y. Fluorescence quenching was recorded at 544 nm after excitation at 425 nm. For AML and PER, calibration curves were obtained over the range of 0.3–3.0 µg/mL and 0.2–2.0 µg/mL, respectively, with correlation coefficients of 0.9993 and 0.9995, respectively. The developed method was validated according to ICH guidelines. The proposed spectrofluorimetric method is regarded new and sensitive. As a result, the proposed method might be used to estimate the quality of the cited drugs in their pharmaceutical formulations and biological fluid.
Affective landscapes!
Authors: Althans Birgit 
Published: January 2023

ZusammenfassungDer Beitrag erläutert zunächst einen breiten Kulturbegriff und die Transformationen des ländlichen Raums durch den globalen Kapitalismus, die den ländlichen Raum härter treffen als die Städte. Er skizziert die vermehrt auftretenden politisch gerahmten Kulturkämpfe und zeigt, wie Institutionen, Initiativen und Projekte Kultureller Bildung wie auch die Forschung zu Kultureller Bildung versuchen, nicht nur zu vermitteln, sondern neue Wege zu gehen.
Imaging the distribution of bitumen contaminants in shallow coastal plain sands in southwestern Nigeria using electrical resistivity
Authors: Jekayinfa Solomon M. , Oladunjoye Michael A. , Doro Kennedy O. 
Published: January 2023

AbstractNaturally occurring bitumen seeps migrating within the shallow subsurface contaminates soil and groundwater in communities within the eastern segment of the Dahomey Basin in southwestern Nigeria. Managing these contaminations require an understanding of the distribution of the bitumen seeps to isolate contaminated regions to avoid farming activities or drilling shallow drinking water wells within them. Several studies have assessed the shallow occurrence of bitumen in the region, focusing on their economic potentials but ignores the challenges with soil and groundwater contamination in these communities. This study focuses on using electrical resistivity imaging techniques with limited soil cores to delineate the distribution of bitumen seeps within the shallow subsurface in Imakun-Omi community in southwestern Nigeria. We used both 1D and 2D numerical and field approaches in this study. 13 vertical electrical soundings using a Schlumberger electrode array were first acquired to obtain the bulk resistivities and layer thicknesses. The 1D resistivity alongside well lithologic data served as prior data for a forward modelling study to assess the capability of resolving the bitumen seeps within electrically resistive coastal sands. Results of the forward modelling studies guided the acquisition of five 2D electrical resistivity profiles used to image the distribution of bitumen seeps using a Wenner electrode array with a unit electrode spacing of 2 m. Results of this study show that bitumen seeps with resistivities greater than 3000 Ohm-m are distributed within the top 4 m in the area and extends down to 10 m in some locations. Our numerical studies show that despite difficulties in imaging bitumen seeps within sediments overlain by higher electrical resistivity layers, reliable results can be derived, thus proving the versatility of electrical resistivity in delineating areas contaminated by bitumen seeps within shallow coastal sands.
Novel Cytocompatible Chitosan Schiff Base Derivative as a Potent Antibacterial, Antidiabetic, and Anticancer Agent
Authors: Omer Ahmed M. , Eltaweil Abdelazeem S. , El-Fakharany Esmail M. , Abd El-Monaem Eman M. , Ismail Magda M. F. , Mohy-Eldin Mohamed S. , Ayoup Mohammed S. 
Published: January 2023

AbstractThis study intends to develop a novel bioactive chitosan Schiff base (CTS-SB) derivative via coupling of chitosan (CTS) with 4-((5, 5-dimethyl-3-oxocyclohex-1-en-1-yl) amino) benzene-sulfonamide. The alteration in the chemical structure of CTS-SB was verified using1H NMR and FT-IR analysis, while the thermal and morphological properties were inspected by TGA and SEM characterization tools, respectively. Ion exchange capacity of the developed CTS-SB derivative recorded a maximal value of 12.1 meq/g compared to 10.1 meq/g for pristine CTS. In addition, antibacterial activity of CTS-SB derivative was greatly boosted againstEscherichia coli(E coli) andStaphylococcus aureus(S. aureus) bacteria. Minimum inhibition concentration of CTS-SB derivative was perceived at 50 µg/mL, while the highest concentration (250 µg/mL) could inhibit the growth ofS. aureusup to 91%. What’s more, enhanced antidiabetic activity by CTS-SB derivative, which displayed higher inhibitory values of α-amylase (57.9%) and α-glucosidase (63.9%), compared to those of pure CTS (49.8 and 53.4%), respectively Furthermore, cytotoxicity investigation on HepG-2 cell line revealed potential anticancer activity along with good safety margin against primary human skin fibroblasts (HSF cells) and decent cytocompatibility. Collectively, the gained results hypothesized that CTS-SB derivative could be effectively applied as a promising antibacterial, anticancer and antidiabetic agent for advanced biomedical applications.
Sustainability Transitions in E-commerce Research—Academic Achievements and Impediments
Authors: Zhang Mengzhen 
Published: January 2023

AbstractTo date, the COVID-19 pandemic has led to the blossoming of e-commerce, which has brought both advantages and impediments to a more sustainable future. The central aim of sustainability transitions (ST) research conceptualizes and explains how radical changes can occur in the way that societal and environmental functions are fulfilled. Embedding ST logic with e-commerce could help us understand the current standing of e-commerce, and lead to solutions applied from its implications. However, there is a lack of research that pivots ST into the context of e-commerce. Thus, this paper fills the gap by conducting a comprehensive literature review to look into how the current e-commerce research fits into the ST framework. We find that the current sustainable e-commerce research is unevenly scattered alongside different dimensions, and there is an urgency to employ government power and drive public awareness. This paper extends the scope of ST into the e-commerce context; solutions for practitioners to achieve effective governance have been particularly emphasized.
Ultra-broadband pulse generation via hollow-core fiber compression and frequency doubling for ultra-intense lasers
Authors: Li Yanyan , Shao Beijie , Peng Yujie , Qian Junyu , Li Wenkai , Wang Xinliang , Liu Xingyan , Lu Xiaoming , Xu Yi , Leng Yuxin , Li Ruxin 
Published: January 2023

Abstract
We demonstrate an ultra-broadband high temporal contrast infrared laser source based on cascaded optical parametric amplification, hollow-core fiber (HCF) and second harmonic generation processes. In this setup, the spectrum of an approximately 1.8 μm laser pulse has near 1 μm full bandwidth by employing an argon gas-filled HCF. Subsequently, after frequency doubling with cascaded crystals and dispersion compensation by a fused silica wedge pair, 9.6 fs (~3 cycles) and 150 μJ pulses centered at 910 nm with full bandwidth of over 300 nm can be generated. The energy stability of the output laser pulse is excellent with 0.8% (root mean square) over 20 min, and the temporal contrast is >1012 at –10 ps before the main pulse. The excellent temporal and spatial characteristics and stability make this laser able to be used as a good seed source for ultra-intense and ultrafast laser systems.
The Spirit of Christianity and Law
Authors: Domingo Rafael 
Published: January 2023

AbstractThis essay offers an analysis John Witte, Jr.’s contribution to the study of the relationship between Christianity and law as an autonomous branch within the broad field of law and religion. The author discusses Witte as a Christian jurist educated in Reformed Protestantism and influenced by Abraham Kuyper and Harold J. Berman, among others, and describes and evaluates the interdisciplinary, interdenominational, and international project on Christianity and law headed by Witte, to which more than five hundred scholars (jurists, theologians, philosophers, historians, and sociologists) are contributing. Witte analyzes the interaction between Christianity and law from a relational, biographical, and jurisprudential perspective, and underlying his project is the idea that the relationship between Christianity and law is not merely accidental, but has a metahistorical significance and an enduring value for the development of humanity. Although the project has already borne much fruit, there is room for further maturity and methodological purity as it is still in its early stages.
Free Riding, Network Effects, and Burden Sharing in Defense Cooperation Networks
Authors: Kinne Brandon J. , Kang Stephanie N. 
Published: January 2023

AbstractHow do states distribute the burdens of collective defense? This paper develops a network theory of burden sharing. We focus on bilateral defense cooperation agreements (DCAs), which promote cooperation in a variety of defense, military, and security issue areas. Using a computational model, we show that DCA partners’ defense spending depends on the network structure of their agreements. In bilateral terms, DCAs increase defense spending by committing states to defense activities and allowing partners to reciprocally punish free riding. However, as a state's local network of defense partnerships grows more densely connected, with many transitive “friend of a friend” relations, DCAs have the countervailing effect of reducing defense spending. The more deeply integrated states are in bilateral defense networks, the less they spend on defense. We distinguish two potential mechanisms behind this effect—one based on efficiency improvements, the other on free riding. An empirical analysis using multilevel inferential network models points more to efficiency than to free riding. Defense networks reduce defense spending, and they do so by allowing countries to produce security more efficiently.
Impact of the COVID-19 pandemic on pregnancy postponement – evidence from Japan
Authors: Matsushima Midori , Yamada Hiroyuki , Kondo Naoki , Arakawa Yuki , Tabuchi Takahiro 
Published: January 2023

AbstractJapan has faced a decline in fertility since the coronavirus disease 2019 (COVID-19) pandemic. This study aimed to investigate the rate of pregnancy postponement and its contributing factors, with a particular focus on economic- and COVID-19 infection-related indicators. This study used data from 768 observations of married women aged 18 to 50 years with pregnancy intentions. The data were obtained from two rounds of a large web-based survey conducted by the Japan COVID-19 and Society Internet Survey (JACSIS) in 2020 and 2021. A generalised estimating equation (GEE) model was employed, as well as Poisson regression models for sub-sample analysis divided by year to estimate the year differential magnitude of the contributing factors’ impacts. Approximately 20% of married women with childbearing intentions postponed their childbearing. The analyses revealed that declining income and anxiety about future household finances were significantly related to delayed childbearing, while fear of COVID-19 and infection rate were not. Additionally, the adverse effects of unfavourable economic conditions were stronger in 2021. Notably, age did not influence the decision of pregnancy postponement. Older women postponed pregnancy just as much as younger women. In conclusion, this study confirmed that the COVID-19 pandemic, particularly its related adverse economic conditions, contributed to Japan’s current baby bust. Considering that advanced maternal age is already common in Japan, this decreased fertility may result in the long-term negative consequence of further population decline.
Spatial parasitology and the unmapped human helminthiases
Authors: Schluth Catherine G. , Standley Claire J. , Bansal Shweta , Carlson Colin J. 
Published: January 2023

AbstractHelminthiases are a class of neglected tropical diseases that affect at least 1 billion people worldwide, with a disproportionate impact on resource-poor areas with limited disease surveillance. Geospatial methods can offer valuable insights into the burden of these infections, particularly given that many are subject to strong ecological influences on the environmental, vector-borne or zoonotic stages of their life cycle. In this study, we screened 6829 abstracts and analysed 485 studies that use maps to document, infer or predict transmission patterns for over 200 species of parasitic worms. We found that quantitative mapping methods are increasingly used in medical parasitology, drawing on One Health surveillance data from the community scale to model geographic distributions and burdens up to the regional or global scale. However, we found that the vast majority of the human helminthiases may be entirely unmapped, with research effort focused disproportionately on a half-dozen infections that are targeted by mass drug administration programmes. Entire regions were also surprisingly under-represented in the literature, particularly southern Asia and the Neotropics. We conclude by proposing a shortlist of possible priorities for future research, including several neglected helminthiases with a burden that may be underestimated.
JUSTIN CONNOLLY IN INTERVIEW
Authors: Kurowski Andrew 
Published: January 2023

AbstractIn this transcription of an interview between the former Editor of New Music at BBC Radio 3 and the composer Justin Connolly, Connolly discusses his life as a composer. He traces his development from childhood to studies at the Royal College of Music and Yale University and the influence of the composer Roberto Gerhard. Connolly's Poems of Wallace Stevens IV, his most recent work at the time of the interview, is considered in particular detail. The interview took place at the former British Music Information Centre in Stratford Place, London on 14 April 1993. TEMPO gratefully acknowledges the work of the Estate of Justin Connolly in transcribing the interview and permitting its publication.
(Im)mobile ageing: risks of exclusion in later life in liminal urban peripheries
Authors: Nagesh Prajwal , Bailey Ajay , George Sobin , Hyde Martin , Subaiya Lekha 
Published: January 2023

AbstractDespite the recent policy impetus for age-friendly cities, there is still scope for more geographical insights into ageing in low- and middle-income countries (LMICs). Cities in LMICs, such as Bengaluru (India), are witnessing an increase in the size of the older population in their peripheral urban regions, but there is relatively little understanding of the risks of exclusion in later age in these liminal zones. This study, set in a peripheral ward of Bengaluru, focuses on the experiences of exclusion/inclusion of socio-economically marginalised older adults and their access to work, health care and leisure. The research uses a multidimensional old-age exclusion framework to highlight how the domains of neighbourhood, material resources, mobility infrastructure and social relations influence the risks for social exclusion. We use a qualitative approach by combining behavioural mapping and in-depth interviews. Our findings highlight some ways in which institutionalised exclusion from civic infrastructure accentuates the precariousness of ageing. The rigidity of traditional hierarchies in peri-urban regions has meant that older adults who were poor, women and belonged to marginalised castes experience constrained mobilities to access labour markets, health care and social life, compounding their place-based exclusion. Despite social networks and solidarities, older adults on the periphery faced individualisation of risks while trying to access the basic amenities, thereby falling between the gap of the urban–rural milieu and governance. Age-friendly cities need to accommodate such hybrid transitionary urban processes, in the absence of which, active ageing in these rising peripheries can be impeded.