bluuebunny/crossref_metadata_2025_split huggingface dataset:
Energy-efficient high-fidelity image reconstruction with memristor arrays for medical diagnosis
Authors: Zhao Han , Liu Zhengwu , Tang Jianshi , Gao Bin , Qin Qi , Li Jiaming , Zhou Ying , Yao Peng , Xi Yue , Lin Yudeng , Qian He , Wu Huaqiang 
Published: April 2023

AbstractMedical imaging is an important tool for accurate medical diagnosis, while state-of-the-art image reconstruction algorithms raise critical challenges in massive data processing for high-speed and high-quality imaging. Here, we present a memristive image reconstructor (MIR) to greatly accelerate image reconstruction with discrete Fourier transformation (DFT) by computing-in-memory (CIM) with memristor arrays. A high-accuracy quasi-analogue mapping (QAM) method and generic complex matrix transfer (CMT) scheme was proposed to improve the mapping precision and transfer efficiency, respectively. High-fidelity magnetic resonance imaging (MRI) and computed tomography (CT) image reconstructions were demonstrated, achieving software-equivalent qualities and DICE scores after segmentation with nnU-Net algorithm. Remarkably, our MIR exhibited 153× and 79× improvements in energy efficiency and normalized image reconstruction speed, respectively, compared to graphics processing unit (GPU). This work demonstrates MIR as a promising high-fidelity image reconstruction platform for future medical diagnosis, and also largely extends the application of memristor-based CIM beyond artificial neural networks.
Metagenome and metabolome insights into the energy compensation and exogenous toxin degradation of gut microbiota in high-altitude rhesus macaques (Macaca mulatta)
Authors: Zhao Junsong , Yao Yongfang , Li Diyan , Zhu Wei , Xiao Hongtao , Xie Meng , Xiong Ying , Wu Jiayun , Ni Qingyong , Zhang Mingwang , Xu Huailiang 
Published: April 2023

AbstractThere have been many reports on the genetic mechanism in rhesus macaques (RMs) for environmental adaptation to high altitudes, but the synergistic involvement of gut microbiota in this adaptation remains unclear. Here we performed fecal metagenomic and metabolomic studies on samples from high- and low-altitude populations to assess the synergistic role of gut microbiota in the adaptation of RMs to high-altitude environments. Microbiota taxonomic annotation yielded 7471 microbiota species. There were 37 bacterial species whose abundance was significantly enriched in the high-altitude populations, 16 of which were previously reported to be related to the host’s dietary digestion and energy metabolism. Further functional gene enrichment found a stronger potential for gut microbiota to synthesize energy substrate acetyl-CoA using CO2 and energy substrate pyruvate using oxaloacetate, as well as a stronger potential to transform acetyl-CoA to energy substrate acetate in high-altitude populations. Interestingly, there were no apparent differences between low-altitude and high-altitude populations in terms of genes enriched in the main pathways by which the microbiota consumed the three energy substrates, and none of the three energy substrates were detected in the fecal metabolites. These results strongly suggest that gut microbiota plays an important energy compensatory role that helps RMs to adapt to high-altitude environments. Further functional enrichment after metabolite source analysis indicated the abundance of metabolites related to the degradation of exogenous toxins was also significantly higher in high-altitude populations, which suggested a contributory role of gut microbiota to the degradation of exogenous toxins in wild RMs adapted to high-altitude environments.
A history of mild shocks experienced by the regolith particles on hydrated asteroid Ryugu
Authors: Tomioka Naotaka , Yamaguchi Akira , Ito Motoo , Uesugi Masayuki , Imae Naoya , Shirai Naoki , Ohigashi Takuji , Kimura Makoto , Liu Ming-Chang , Greenwood Richard C. , Uesugi Kentaro , Nakato Aiko , Yogata Kasumi , Yuzawa Hayato , Kodama Yu , Hirahara Kaori , Sakurai Ikuya , Okada Ikuo , Karouji Yuzuru , Okazaki Keishi , Kurosawa Kosuke , Noguchi Takaaki , Miyake Akira , Miyahara Masaaki , Seto Yusuke , Matsumoto Toru , Igami Yohei , Nakazawa Satoru , Okada Tatsuaki , Saiki Takanao , Tanaka Satoshi , Terui Fuyuto , Yoshikawa Makoto , Miyazaki Akiko , Nishimura Masahiro , Yada Toru , Abe Masanao , Usui Tomohiro , Watanabe Sei-ichiro , Tsuda Yuichi 
Published: April 2023

AbstractMicrometeorites, a possible major source of Earth’s water, are thought to form from explosive dispersal of hydrated chondritic materials during impact events on their parental asteroids. However, this provenance and formation mechanism have yet to be directly confirmed using asteroid returned samples. Here, we report evidence of mild shock metamorphism in the surface particles of asteroid Ryugu based on electron microscopy. All particles are dominated by phyllosilicates but lack dehydration textures, which are indicative of shock-heating temperatures below ~500 °C. Microfault-like textures associated with extensively shock-deformed framboidal magnetites and a high-pressure polymorph of Fe–Cr–sulfide have been identified. These findings indicate that the average peak pressure was ~2 GPa. The vast majority of ejecta formed during impact on Ryugu-like asteroids would be hydrated materials, larger than a millimetre, originating far from the impact point. These characteristics are inconsistent with current micrometeorite production models, and consequently, a new formation mechanism is required.
Structural basis of centromeric cohesion protection
Authors: García-Nieto Alberto , Patel Amrita , Li Yan , Oldenkamp Roel , Feletto Leonardo , Graham Joshua J. , Willems Laureen , Muir Kyle W. , Panne Daniel , Rowland Benjamin D. 
Published: April 2023

AbstractIn the early stages of mitosis, cohesin is released from chromosome arms but not from centromeres. The protection of centromeric cohesin by SGO1 maintains the sister chromatid cohesion that resists the pulling forces of microtubules until all chromosomes are attached in a bipolar manner to the mitotic spindle. Here we present the X-ray crystal structure of a segment of human SGO1 bound to a conserved surface of the cohesin complex. SGO1 binds to a composite interface formed by the SA2 and SCC1RAD21 subunits of cohesin. SGO1 shares this binding interface with CTCF, indicating that these distinct chromosomal regulators control cohesin through a universal principle. This interaction is essential for the localization of SGO1 to centromeres and protects centromeric cohesin against WAPL-mediated cohesin release. SGO1–cohesin binding is maintained until the formation of microtubule–kinetochore attachments and is required for faithful chromosome segregation and the maintenance of a stable karyotype.
CRAFTED: An exploratory database of simulated adsorption isotherms of metal-organic frameworks
Authors: Oliveira Felipe Lopes , Cleeton Conor , Neumann Barros Ferreira Rodrigo , Luan Binquan , Farmahini Amir H. , Sarkisov Lev , Steiner Mathias 
Published: April 2023

AbstractGrand Canonical Monte Carlo is an important method for performing molecular-level simulations and assisting the study and development of nanoporous materials for gas capture applications. These simulations are based on the use of force fields and partial charges to model the interaction between the adsorbent molecules and the solid framework. The choice of the force field parameters and partial charges can significantly impact the results obtained, however, there are very few databases available to support a comprehensive impact evaluation. Here, we present a database of simulations of CO2 and N2 adsorption isotherms on 690 metal-organic frameworks taken from the CoRE MOF 2014 database. We performed simulations with two force fields (UFF and DREIDING), six partial charge schemes (no charges, Qeq, EQeq, MPNN, PACMOF, and DDEC), and three temperatures (273, 298, 323 K). The resulting isotherms compose the Charge-dependent, Reproducible, Accessible, Forcefield-dependent, and Temperature-dependent Exploratory Database (CRAFTED) of adsorption isotherms.
Product, building, and infrastructure material stocks dataset for 337 Chinese cities between 1978 and 2020
Authors: Li Xiang , Song Lulu , Liu Qiance , Ouyang Xin , Mao Ting , Lu Haojie , Liu Litao , Liu Xiaojie , Chen Weiqiang , Liu Gang 
Published: April 2023

AbstractReliable city-level product, building, and infrastructure material stocks data are essential for understanding historical material use patterns, benchmarking material efficiency, and informing future recycling potentials. However, such urban material stocks data are often limited, due primarily to unavailable, inconsistent, or noncontinuous city-level statistics. Here, we provided such an Urban Product, Building, and Infrastructure Material Stocks (UPBIMS) dataset for China, a country that has undergone a remarkable urbanization process in the past decades, by collating different official statistics and applying various gap-filling methods. This dataset contains the stock of 24 materials contained in 10 types of products, buildings, and infrastructure in all 337 prefecture-level cities in China from 1978 to 2020. This quality controlled and unified dataset is the first of its kind with such a full coverage of all prefecture-level Chinese cities and can be used in a variety of applications, for example in urban geography, industrial ecology, circular economy, and climate change mitigation. Every piece of data is tagged with its source and the dataset will be periodically updated.
The intracellular domain of major histocompatibility class-I proteins is essential for maintaining excitatory spine density and synaptic ultrastructure in the brain
Authors: Lazarczyk Maciej J. , Eyford Brett A. , Varghese Merina , Arora Hitesh , Munro Lonna , Warda Tahia , Pfeifer Cheryl G. , Sowa Allison , Dickstein Daniel R. , Rumbell Timothy , Jefferies Wilfred A. , Dickstein Dara L. 
Published: April 2023

AbstractMajor histocompatibility complex class I (MHC-I) proteins are expressed in neurons, where they regulate synaptic plasticity. However, the mechanisms by which MHC-I functions in the CNS remains unknown. Here we describe the first structural analysis of a MHC-I protein, to resolve underlying mechanisms that explains its function in the brain. We demonstrate that Y321F mutation of the conserved cytoplasmic tyrosine-based endocytosis motif YXXΦ in MHC-I affects spine density and synaptic structure without affecting neuronal complexity in the hippocampus, a region of the brain intimately involved in learning and memory. Furthermore, the impact of the Y321F substitution phenocopies MHC-I knock-out (null) animals, demonstrating that reverse, outside-in signalling events sensing the external environment is the major mechanism that conveys this information to the neuron and this has a previously undescribed yet essential role in the regulation of synaptic plasticity.
Uncovering spatial and social gaps in rural mobility via mobile phone big data
Authors: Liu Zhengying , Zhao Pengjun , Liu Qiyang , He Zhangyuan , Kang Tingting 
Published: April 2023

AbstractRural mobility inequality is an important aspect of inequality-focused Sustainable Development Goals. To reduce inequality and promote global sustainable development, more insight is needed into human mobility patterns in rural areas. However, studies on rural human mobility are scarce, limiting our understanding of the spatial and social gaps in rural human mobility and our ability to design policies for social equality and global sustainable development. This study, therefore, explores human mobility patterns in rural China using mobile phone data. Mapping the relative frequency of short-distance trips across rural towns, we observed that geographically peripheral populations tend to have a low percentage of short-distance flows. We further revealed social gaps in mobility by fitting statistical models: as travel distances increased, human movements declined more rapidly among vulnerable groups, including children, older people, women, and low-income people. In addition, we found that people living with low street density, or in rural towns in peripheral cities with long distances to city borders, are more likely to have low intercity movement. Our results show that children, older adults, women, low-income individuals, and geographically peripheral populations in rural areas are mobility-disadvantaged, providing insights for policymakers and rural planners for achieving social equality by targeting the right groups.
Long-term impact of pulses and organic amendments inclusion in cropping system on soil physical and chemical properties
Authors: Nath C. P. , Dutta Asik , Hazra K. K. , Praharaj C. S. , Kumar Narendra , Singh S. S. , Singh Ummed , Das Krishnashis 
Published: April 2023

AbstractMono-cropping of maize–wheat, mechanical disintegration of soils, and continuous chemical fertilization have deteriorated soil health in the Indo-Gangetic Plains. We studied the long-term impact of pulse-based cropping systems with integrated nutrient management on soil physical and chemical properties and yield sustainability. We evaluated four different cropping systems: (1) maize–wheat (M–W), (2) maize–wheat–mungbean (M–W–Mb), (3) maize–wheat–maize–chickpea (M–W–M–C), (4) pigeonpea–wheat (P–W) each with three degrees of soil fertilization techniques: (1) unfertilized control (CT), (2) inorganic fertilization (RDF), and (3) integrated nutrient management (INM). The field experiment was undertaken in a split-plot design with three replications each year with a fixed layout. P–W and M–W–Mb systems enhanced soil properties such as volume expansion by 9–25% and porosity by 7–9% (p < 0.05) more than M–W, respectively. P–W and M–W–Mb increased soil organic carbon by 25–42% and 12–50% over M–W (RDF). P–W system enhanced water holding capacity and gravimetric moisture content by 10 and 11% (p < 0.05) than M–W. Pulse-based systems (P–W and M–W–Mb) had higher available nitrogen (8–11%), phosphorus (42–73%), and potassium (8–12%) over M–W (p < 0.05). M–W–Mb increased 26% maize yield and 21% wheat yield over M–W (p < 0.05) at the thirteenth crop cycle. P–W system had a higher sustainable yield index (p < 0.05) of wheat over the M–W. Thus, pulse inclusion in the cropping system in combination with INM can enhance physical and chemical properties vis-à-vis sustainable yield index over the cereal-cereal system.
Encoding of speech in convolutional layers and the brain stem based on language experience
Authors: Beguš Gašper , Zhou Alan , Zhao T. Christina 
Published: April 2023

AbstractComparing artificial neural networks with outputs of neuroimaging techniques has recently seen substantial advances in (computer) vision and text-based language models. Here, we propose a framework to compare biological and artificial neural computations of spoken language representations and propose several new challenges to this paradigm. The proposed technique is based on a similar principle that underlies electroencephalography (EEG): averaging of neural (artificial or biological) activity across neurons in the time domain, and allows to compare encoding of any acoustic property in the brain and in intermediate convolutional layers of an artificial neural network. Our approach allows a direct comparison of responses to a phonetic property in the brain and in deep neural networks that requires no linear transformations between the signals. We argue that the brain stem response (cABR) and the response in intermediate convolutional layers to the exact same stimulus are highly similar without applying any transformations, and we quantify this observation. The proposed technique not only reveals similarities, but also allows for analysis of the encoding of actual acoustic properties in the two signals: we compare peak latency (i) in cABR relative to the stimulus in the brain stem and in (ii) intermediate convolutional layers relative to the input/output in deep convolutional networks. We also examine and compare the effect of prior language exposure on the peak latency in cABR and in intermediate convolutional layers. Substantial similarities in peak latency encoding between the human brain and intermediate convolutional networks emerge based on results from eight trained networks (including a replication experiment). The proposed technique can be used to compare encoding between the human brain and intermediate convolutional layers for any acoustic property and for other neuroimaging techniques.
Searching for sliding surfaces in multi-level loess slopes based on the brachistochrone
Authors: Yang Kui-bin , Zhu Yan-peng 
Published: April 2023

AbstractAs a key problem in slope-stability analysis, searching for potential sliding surfaces has attracted the attention of experts and scholars for a long time. However, the commonly used sliding surface curves are only considered in terms of shape approximation and lack physical significance. The search process involved in stability analysis of multi-level slopes is complex and a large amount of calculation is required. In order to solve this problem, this paper proposes a new sliding surface form based on physical interpretation of the brachistochrone, and establishes a search model for the brachistochrone sliding surface of a multi-level loess slope. At the same time, in order to further expand the search range and find a more ideal potential sliding surface curve shape and position with a lower safety factor, we recommend continuing the sliding-surface search after the brachistochrone is improved. We compared the calculation results for the position of the potential sliding surface and the stability safety factor with the corresponding results for an arc sliding surface (in combination with a calculation example) to verify its rationality. The approach offered here not only provides a new choice of sliding surface curve form for slope-stability analysis, but also significantly improves search efficiency for potential sliding surfaces of multi-level loess slopes.
Highly sensitive low-frequency-detectable acoustic sensor using a piezoresistive cantilever for health monitoring applications
Authors: Okamoto Yuki , Nguyen Thanh-Vinh , Takahashi Hidetoshi , Takei Yusuke , Okada Hironao , Ichiki Masaaki 
Published: April 2023

AbstractThis study investigates a cantilever-based pressure sensor that can achieve a resolution of approximately 0.2 mPa, over the frequency range of 0.1–250 Hz. A piezoresistive cantilever with ultra-high acoustic compliance is used as the sensing element in the proposed pressure sensor. We achieved a cantilever with a sensitivity of approximately 40 times higher than that of the previous cantilever device by realizing an ultrathin (340 nm thick) structure with large pads and narrow hinges. Based on the measurement results, the proposed pressure sensor can measure acoustic signals with frequencies as low as 0.1 Hz. The proposed pressure sensor can be used to measure low-frequency pressure and sound, which is crucial for various applications, including photoacoustic-based gas/chemical sensing and monitoring of physiological parameters and natural disasters. We demonstrate the measurement of heart sounds with a high SNR of 58 dB. We believe the proposed microphone will be used in various applications, such as wearable health monitoring, monitoring of natural disasters, and realization of high-resolution photoacoustic-based gas sensors. We successfully measured the first (S1) and second (S2) cardiac sounds with frequencies of 7–100 Hz and 20–45 Hz, respectively.
Effect of remdesivir post-exposure prophylaxis and treatment on pathogenesis of measles in rhesus macaques
Authors: Peart Akindele Nadine A. , Katamoni Laharika Dasharath , Brockhurst Jacqueline , Ghimire Shristi , Suwanmanee San , Pieterse Lisa , Metcalf Pate Kelly A. , Bunyan Elaine , Bannister Roy , Cihlar Tomas , Porter Danielle P. , Griffin Diane E. 
Published: April 2023

AbstractMeasles is a systemic disease initiated in the respiratory tract with widespread measles virus (MeV) infection of lymphoid tissue. Mortality can be substantial, but no licensed antiviral therapy is available. We evaluated both post-exposure prophylaxis and treatment with remdesivir, a broad-spectrum antiviral, using a well-characterized rhesus macaque model of measles. Animals were treated with intravenous remdesivir for 12 days beginning either 3 days after intratracheal infection (post-exposure prophylaxis, PEP) or 11 days after infection at the onset of disease (late treatment, LT). As PEP, remdesivir lowered levels of viral RNA in peripheral blood mononuclear cells, but RNA rebounded at the end of the treatment period and infectious virus was continuously recoverable. MeV RNA was cleared more rapidly from lymphoid tissue, was variably detected in the respiratory tract, and not detected in urine. PEP did not improve clinical disease nor lymphopenia and reduced the antibody response to infection. In contrast, LT had little effect on levels of viral RNA or the antibody response but also did not decrease clinical disease. Therefore, remdesivir transiently suppressed expression of viral RNA and limited dissemination when provided as PEP, but virus was not cleared and resumed replication without improvement in the clinical disease parameters evaluated.
Comparison of the neuromuscular response to three different Turkish, semi-professional football training sessions typically used within the tactical periodization training model
Authors: Garrett Joel M. , Leduc Cedric , Akyildiz Zeki , van den Hoek Daniel J. , Clemente Filipe Manuel , Yildiz Mehmet , Nobari Hadi 
Published: April 2023

AbstractThis study examined the neuromuscular responses to three typical football (soccer) training sessions and the reliability of peak speed (PS) measured during a submaximal running test (SRT) for identifying neuromuscular fatigue (NMF) status. Jump height (CMJH) and peak velocity (CMJPV) were collected from a CMJ test, while peak speed (PS) was collected during an SRT before and after each training session. Large effect size (ES) decreases were observed in each variable post-training (ES; − 1.42 to − 2.32). Significant differences (> 0.001) were detected between each football session's external load variables. Coefficients of variations were small (< 10%) with moderate (CMJPV; 0.53, PS; 0.44) and strong (CMJH; 0.72) intraclass correlation coefficients between pre-test measures. The demands of each football session aligned with the principles of tactical periodization and were sufficient to produce the fatigue necessary to elicit physiological adaptations. PS was also shown to be a viable measure of monitoring NMF status.
Some new soliton solutions of a semi-discrete fractional complex coupled dispersionless system
Authors: Abdel Kader A. H. , El Bialy F. , Nour H. M. , Abdel Latif M. S. 
Published: April 2023

AbstractIn this paper, a semi-discrete fractional derivative complex coupled dispersionless system is proposed. The properties of M-fractional derivative are utilized to convert discrete M-fractional derivative system to a classical discrete differential system. Then the invariant subspace method (ISM) is utilized to find dark, bright, kink and W-shaped soliton solutions for the proposed system.