bluuebunny/crossref_metadata_2025_split huggingface dataset:
Identifying developmental QTL alleles with favorable effect on grain yield components under late‐terminal drought in spring barley MAGIC population
Authors: Afsharyan Nazanin P. , Sannemann Wiebke , Ballvora Agim , Léon Jens 
Published: August 2023

AbstractBarley is the fourth most cultivated cereal worldwide, and drought is a major cause of its yield loss by negatively affecting its development. Hence, better understanding developmental mechanisms that control complex polygenic yield‐related traits under drought is essential to uncover favorable yield regulators. This study evaluated seven above‐ground yield‐related traits under well‐watered (WW) and late‐terminal drought (TD) treatment using 534 spring barley multiparent advanced generation intercross double haploid (DH) lines. The analysis of quantitative trait loci (QTL) for WW, TD, marker by treatment interaction, and drought stress tolerance identified 69, 64, 25, and 25 loci, respectively, for seven traits from which 15 loci were common for at least three traits and 17 were shared by TD and drought stress tolerance. Evaluation of allelic effects for a QTL revealed varying effect of parental alleles. Results showed prominent QTL located on major flowering time gene Ppd‐H1 with favorable effects for grain weight under TD when flowering time was not significantly affected, suggesting that this gene might be linked with increasing grain weight by ways other than timing of flowering under late‐terminal drought stress. Furthermore, a desirable novel QTL allele was identified on chromosome 5H for grain number under TD nearby sucrose transporter gene HvSUT2. The findings indicated that spring barley multiparent advanced generation intercross population can provide insights to improve yield under complex condition of drought.
A review of electromyography techniques of the cervical paraspinal muscles
Authors: McGuire Tyler , Haig Andrew J. 
Published: August 2023

AbstractElectrodiagnosis for cervical radiculopathy often involves exploration of the cervical paraspinal muscles. Accurate and reproducible results require a technique with specific anatomic localization, direction of insertion, extent of insertion, scoring system for insertion, and criteria for determining abnormality. We sought to understand if a published technique met these criteria. A Medline search found 39 articles with original research and 10 review articles involving the cervical paraspinals. A library search found 19 textbooks since 2000, but 9 were not available. Only two studies were specific to the question. Neither had reproducible techniques and they contradicted each other. Studies in which the paraspinals were used for comparison or inclusion did not provide any specific technique. The review articles and textbooks typically met none of our criteria and the few that discussed technique at all provided no reproducible methods. Despite 80 years of electrodiagnostic testing, there is no useful, reproducible technique for exploring the cervical paraspinal muscles. Yet such a paraspinal mapping technique has proven invaluable in the lumbar region. For cervical electromyography to be of value, the next step is to understand the anatomy and propose a reproducible technique. Subsequent research will determine whether the neck muscles are helpful in the diagnosis of cervical radiculopathy. The absence of a valid reproducible cervical paraspinal technique impedes clinical and scientific understanding of cervical radiculopathy.
Diisocyanate‐based chain extension via Mg(II) catalyzed amide formation to high‐molecular‐weight poly(lactic acid)
Authors: Kawashima Nobuyuki , Usugi Shin‐ichi , Ogawa Ryohei 
Published: August 2023

AbstractA simple chain‐extension reaction using diisocyanate as a chain extender was adopted to increase the molecular weight of low‐molecular‐weight (LMW) poly(lactic acid) (PLA) synthesized via direct polycondensation and to recover the molecular weight of commercial PLA after service life. The slow reaction between diisocyanate and the carboxylic acid terminus of PLA was successfully accelerated using a Mg(II) catalyst, affording a linear chain‐extended PLA (cePLA) connected through amide bonds. To increase the number of amide bonds, which exhibit higher thermal stability than the urethane bonds that are formed in the more common chain‐extension reactions between isocyanates and the hydroxy terminus of PLA, a telechelic LMW‐PLA having carboxylic acid groups at both termini was prepared. Subsequent reaction of this LMW‐PLA with diisocyanate in the presence of a Mg(II) catalyst afforded a cePLA with high molecular weight (Mw > 180 × 103 g/mol) and enhanced stability against thermal degradation, while showing identical mechanical properties and biodegradability as commercial PLA.
Universal assessment and tiered intervention: A model of care to meet the pediatric oncology psychosocial standard of care for school support
Authors: Kirkpatrick Kathryn , Irwin Mary Kay , Young‐Saleme Tammi , Brown Najah N. , Vannatta Kathryn 
Published: August 2023

AbstractObjectiveThe feasibility and acceptability of a tiered intervention model of school intervention services was investigated in response to the publication of evidence‐based Psychosocial Standards of Care for Children with Cancer and their Families.MethodChildren with newly diagnosed malignancy or transitioning to long‐term survivorship care were eligible. Families received universal school needs assessment and intervention targeted at the level of risk identified. Academic risk and resource utilization data collected over 1 year were used to evaluate model feasibility and surveys evaluated family and medical provider satisfaction with the model.ResultsOne hundred and eight children were enrolled and had academic risk assessed at enrollment as high (25%), moderate (44.4%) or low (30.6%) risk. School liaison staff time spent providing intervention was related to the level of risk. 54.6% of patients reported a decrease in risk status at the end of 1 year of intervention. Parents (94%) and medical providers (100%) chose responses of “agree” or “strongly agree” when asked if they were satisfied with the intervention received over the year.ConclusionsThe tiered model of care identifies the students with the highest need for intervention, allows for more targeted use of resources, and successfully meets the Psychosocial Standard of Care for academic needs.
The association between PM2.5 concentration and the severity of acute asthmatic exacerbation in hospitalized children: A retrospective study in Chongqing, China
Authors: Zhang Yueming , Xu Ximing , Zhang Guangli , Li Qinyuan , Luo Zhengxiu 
Published: August 2023

AbstractBackgroundAmbient PM2.5 is associated with asthma exacerbation. The association between the concentration of PM2.5 and the severity of asthma exacerbation has yet to be thoroughly clarified. The study aims to explore the association between the piror 30 days average concentration of PM2.5 and the severity of acute asthma exacerbation in hospitalized children.MethodsA total of 269 children with acute exacerbation of asthma were enrolled and divided into three groups according to the PM2.5 exposure concentrations: group 1 (PM2.5: <37.5 μg/m3), group 2 (PM2.5: 37.5–75 μg/m3), group 3 (PM2.5: ≥75 μg/m3), respectively. The ordered logistic regression modeling was conducted to explore the influence of daily PM2.5 concentration on the clinical severity of children's asthma exacerbation. Multiple linear regression was conducted to explore the association between the concentration of PM2.5 and the length of stay in the hospital (LOS). We also conducted a receiver operating characteristic (ROC) curve analysis to explore the cutoff value of PM2.5 to predict the children's asthma exacerbation.ResultsThere was no statistical difference among the three groups of children in gender, age, body mass index, ethnicity, the first diagnosis of asthma, allergic history, passive smoke exposure, or family history of asthma. There was a statistically significant difference in many hospitalization characteristics (p < 0.05) among the three groups of children. Significant differences were found in terms of accessory muscles of respiration (p = 0.005), respiratory failure (p = 0.012), low respiratory tract infectious (p = 0.020), and the severity of asthma exacerbation (p < 0.001) among the three groups. PM2.5 concentration was primarily positively correlated to neutrophile inflammation. The ordered multivariate logistic regression model showed that higher PM2.5 concentrations were significantly associated with greater odds of more severe asthma exacerbation in one and two‐pollutant models. The adjusted odds ratio of severe asthma exacerbation was 1.029 (1.009, 1.049) in the one‐pollutant model. The most significant odds ratio of severe asthma exacerbation was 1.050 (1.027, 1.073) when controlling NO2 in the two‐pollutant models. Multiple linear regression showed that PM2.5 concentration was significantly associated with longer LOS in both one‐pollutant and two‐pollutant models. By performing ROC analysis, the average daily concentration of 44.5 µg/m3 of PM2.5 (AUC = 0.622, p = 0.002) provided the best performance to predict severe asthma of children exacerbation with a sensitivity of 59.2% and a specificity of 63.8%.ConclusionThe increased prior 30 days average concentration of PM2.5 was associated with greater asthma exacerbation severity and longer length of stay in the hospital of children with asthma exacerbation.
A meta‐analysis and mapping of global mpox infection among children and adolescents
Authors: Suvvari Tarun Kumar , Sandeep Mokanpally , Kumar Jogender , Satapathy Prakasini , Chenchula Santenna , Gandhi Aravind P. , Shamim Muhammad Aaqib , Schlagenhauf Patricia , Rodríguez‐Morales Alfonso J. , Sah Ranjit , Pradhan Keerti Bhusan , Rustagi Sarvesh , Hermis Alaa Hamza , Padhi Bijaya K. 
Published: August 2023

AbstractMonkeypox (mpox) is a significant health concern affecting children and adolescents globally. This systematic review and meta‐analysis aims to synthesise the available evidence on the proportion of children and adolescents affected by the mpox virus. A comprehensive search was conducted in seven electronic databases (PubMed, Scopus, Web of Science, EMBASE, ProQuest, EBSCOHost, and Cochrane) to identify the original reports on mpox cases in children and adolescents till 15 January 2023. Descriptive reports on probable or laboratory‐confirmed mpox in children and adolescents (0–17 years old) were considered eligible. Studies not providing separate data for the above age group and case‐control studies were excluded. The primary outcome was pooled proportion of mpox cases among children and adolescents. Proportion meta‐analysis and heterogeneity between studies were determined using a restricted maximum likelihood estimator, and a random‐effects model was fitted to the data. Sensitivity analysis and subgroup analysis were also conducted. A drapery plot was also provided as a complementary figure to the forest plot. The protocol was prospectively registered with PROSPERO (CRD42023392475). A total of 440 studies were identified, of which 37 were included in the review and 25 in the meta‐analysis (62,701 participants with 3306 children and adolescents). The pooled proportion of children and adolescents was 0.46 (95% CI: 0.30–0.63, I2:100%). The proportion of children and adolescents was significantly lower (p < 0.001) in the ongoing pandemic 0.04 (95% CI: 0.00–0.32) than before 2022 0.62 (95% CI: 0.49–0.74). The meta‐regression showed that the higher the study's sample size, the lower the proportion of children among the mpox cases. Both overall and subgroup heterogeneity were high. Adolescents and children below 5 years are commonly affected by the ongoing pandemic. In conclusion, the high proportion of children affected by the mpox virus highlights the need for increased research and targeted interventions to prevent and control the spread of the virus in this population.
Sustainable energy development through non‐residential rooftop solar photovoltaic adoption: Empirical evidence from India
Authors: Kumar Pradeep , Gupta Sanjeev , Dagar Vishal 
Published: August 2023

AbstractEnvironmental deterioration and climate change are the key issues nowadays that hinder sustainable development, and the consumption of fossil fuel‐based energy sources significantly contributes to the issues. To achieve Sustainable Development Goal‐7 concerning sustainable and clean energy development, deploying non‐conventional energy sources is crucial. Solar energy is considered a significantly clean and sustainable energy source among renewable energy sources. Therefore, the present study attempted to investigate the key factors affecting the adoption of non‐residential Rooftop Solar Photovoltaic (RSPV) systems in Chandigarh, India. The researchers used a descriptive research design to examine the current phenomena. The current study is premised on the perceptions of the users of the non‐residential RSPV system. The data was acquired through a self‐administered survey questionnaire. A complete response from 207 participants was used for analysis purposes. The researchers have used the Partial Least Square‐Structural Equation Modeling strategy to estimate measurement and structural models. The study found that nodal agencies and environmental organizations are crucial in disseminating information and motivations concerning RSPV adoption. The study revealed that the environmental concerns of the users, compatibility, environmental benefits, the immediacy of reward, and trialability were found to be significant drivers of the diffusion and adoption of non‐residential RSPV systems. The study concluded that a paucity of financial incentives and high upfront expenses had been significant blockades to the diffusion and adoption of non‐residential RSPV.
Manufacturing reshoring and sustainable development goals: A home versus host country perspective
Authors: Di Stefano Cristina , Fratocchi Luciano , Martínez‐Mora Carmen , Merino Fernando 
Published: August 2023

AbstractAfter decades of offshoring their manufacturing activities, an increasing number of companies are revising their location strategies and implementing reshoring decisions, including backshoring (relocation in the home country) and nearshoring (relocation in the home region) alternatives. It has been recognized that reshoring strategies are consistent with the sustainable production approach, since they allow companies to produce goods in a manner that is socially beneficial, economically viable, and environmentally less harmful over the whole life cycle of those goods. Additionally, there are early indications that reshoring can also promote and support sustainable consumption approaches. Consequently, reshoring has a wide range of impacts in both the home and the host countries, also in terms of the Sustainable Development Goals (SDGs). However, this topic has received little attention in the extant reshoring literature. This paper seeks to contribute to the discussion by adopting a two‐step approach. Initially, we analyze the very few contributions available on this topic; then, we identify and discuss which of the 17 SDGs are impacted by reshoring decisions at both the home and the host country level. It emerges that reshoring decisions have several and differentiated impacts in terms of SDGs. In general, these impacts are positive for home countries and negative for host ones. For this reason, a trade‐off emerges when a single relocation decision is taken and implemented. Based on this evidence, implications for scholars, managers and policy makers are presented and discussed.
Multi‐Component PtFeCoNi Core‐Shell Nanoparticles on MWCNTs as Promising Bifunctional Catalyst for Oxygen Reduction and Oxygen Evolution Reactions
Authors: Braun Tobias , Dinda Sirshendu , Karkera Guruprakash , Melinte Georgian , Diemant Thomas , Kübel Christian , Fichtner Maximilian , Pammer Frank 
Published: August 2023

AbstractThe development of commercially viable fuel cells and metal‐air batteries requires effective and cheap bifunctional catalysts for the oxygen reduction reaction (ORR) and the oxygen evolution reaction (OER). Multi‐component Pt−Fe−Co−Ni nanoparticles on multi‐walled carbon nanotubes (MWCNTs) were synthesized by wet chemistry route via NaBH4 reduction of metal salts, followed by sintering at different temperatures. The catalyst demonstrates an excellent ORR activity and a promising OER activity in 0.1 m KOH, with a bi‐functional over‐potential, ΔE of 0.83 V, which is comparable to the values of Pt/C or RuO2. Furthermore, it shows outstanding long‐term stability in ORR and OER, namely diffusion limited current density at a potential of 0.3 V decreased just by 5.5 % after 10000 cycles in ORR. The results of the PFCN@NT300 indicate a significant effect of the substitution of Pt by the transition metal (TM) and the formation of nanoparticles on the catalytic performance, especially in the OER.
Oxygen Electrocatalysis by Transition Metal Nitrides: History, Current Trends and Future Prospects
Authors: Ayasha Nadeema , Ahuja Aakash , Mitra Sagar 
Published: August 2023

AbstractThe oxygen reduction and evolution reactions are considered the bottleneck in many electrochemical devices, i. e., fuel cells, water electrolyzers, and metal‐air batteries. The continuous focus has been on inventing and exploring cost‐effective and robust electrocatalysts. Few developed non‐precious metal/metal‐free materials, in fact, outperformed state‐of‐the‐art catalysts during the half‐cell study. However, most of these materials show limited activity during the full cell demonstration, restricting their deployment in commercial energy devices. In this direction, transition metal nitrides (TMNs) have emerged as a potential alternative with peculiar electronic properties and the ease of tuning their intrinsic as well as extrinsic properties. High hardness, refractory nature, d‐band modulation ability and comparatively lower energy for the nitride formation are the other motivations to explore their effectiveness in oxygen electrocatalysis. Considering this, the minireview attempts first to present the properties of catalytic interest, followed by the most viable synthesis approaches in nanoengineering of the TMNs. Next, we provide key trends toward catalytic property modulation for oxygen electrocatalysis, the role of TMNs as potential catalytic support, followed by the effect of TMNs′ in situ autoxidation on the performance. Finally, we state the current limitations of TMNs toward oxygen electrocatalysis, followed by our vision for further advancements.
Polyaniline‐Coated Magnesium Ferrite Nanocomposite: Synthesis, Characterization, Fabrication Cost Analysis and Dye Sorption Behavior with Scale‐Up Design
Authors: Das Subhajit , Pal Anwesha , Debnath Animesh 
Published: August 2023

AbstractIn this research, polyaniline‐based magnesium ferrite nanocomposite (Pan−MgF−NC) was synthesized for the sequestration of cationic brilliant green (BG) dye. The Pan−MgF−NC revealed surface area of 56.19 m2/g and pore volume of 0.056 cc/g, with 20 to 40 nm of pore diameter. The impact of numerous parameters namely, solution pH, sorbent dose, dye initial concentration, and sonication time were explored and maximum dye abatement (90.28 %) was detected at solution pH of 8.0. The dominant mechanisms for the sequestration of BG onto Pan−MgF−NC were π‐π interactions, H‐bonding, and electrostatic attraction. The sorption kinetics of experimental data well fitted to pseudo second order analysis and Langmuir isotherm was the most consistent isotherm model with maximum uptake capability of 294.12 mg/g. Response surface methodology (RSM) was exhibited that the experimental BG removal (88.70 %) and model assimilated BG removal (89.13 %) are close to each other. Investigation related to scale‐up design also studied for large volume of industrial effluent. The laboratory scale fabrication cost of Pan−MgF−NC was found to be ∼85.00 USD/kg. The BG elimination efficacy with Pan−MgF−NC decreases from 90.13 % to 81.93 % after the fifth cycle, demonstrating the strong stability and reusability of Pan−MgF−NC.
Chiral Metal Salen Complexes as Chiral Electrocatalysts for Asymmetric Electrochemical Carboxylation of Acetophenone
Authors: Xiong Rui , Wang Ying , Zhu Jing‐Wei , Li Meng‐Han , Lu Jia‐Xing , Wang Huan 
Published: August 2023

AbstractAsymmetric electrochemical carboxylation is the direct and effective method to fix and utilize CO2, and the selection of chiral catalysts is crucial. In this paper, a series of chiral metal salen complexes are prepared as chiral catalysts to achieve enantioselective conversion of acetophenone with CO2 to synthesis chiral 2‐hydroxy‐2‐phenylpropionic acid under electrochemical conditions. Under the catalysis of NiIIL1, the enantiomeric excess (ee) value of 90 % and yield of 59 % are obtained. By cyclic voltammetry and potentiostatic electrolysis, the effects of metal centers and tert‐butyl groups in ligand structures on the catalytic results are studied and the possible reaction mechanism is proposed.
Synthesis of Coumarin Derivatives Through Pechmann Condensation Reaction of Phenols and β‐Ketoesters using Basalt Fiber Functionalized with 7‐aminonaphthalene‐1,3‐disulfonic acid as a New, Environment Friendly and Recyclable Catalyst
Authors: Bagheri‐Harsini Shoele , Ghorbani‐Vaghei Ramin , Kharazmi Azin 
Published: August 2023

AbstractIn this paper, a series of coumarin derivatives were synthesized, through the Pechmann condensation reaction using basalt fiber functionalized with 7‐aminonaphthalene‐1,3‐disulfonic acid (BF@(CH2)3‐Cl‐ANDSA) as environmentally friendly and heterogeneous catalyst. The structure of the catalyst was identified by FT‐IR, XRD, EDS‐Mapp, FE‐SEM, and TGA analysis. The catalyst was found to be efficient for the synthesis of coumarin derivatives through Pechmann condensation. phenols were treated with β‐ketoesters to give coumarin derivatives, under green conditions. The current method has several advantages, such as non‐toxic, short reaction time, high thermal stability, recyclability, and reusability of the catalyst.
Comprehensive Biological, Photodegradation, Density Functional Theory, and Docking Exploration of Zn(II) and Mn(II) complexes of Piroxicam
Authors: Maha Nasir , Tajammal Affifa , Samra Malka M. , Irfan Ahmad , Laraib Nadeem , Basra Muhammad Asim Raza 
Published: August 2023

AbstractThe biological evaluation of coordination complexes is an active research area ascribed to structural modification and synergistic action due to metal ions. The mononuclear complexes of Zn(II) and Mn(II) piroxicam were evaluated for their encyclopedic biological activities, DFT, and docking exploration. Different antioxidant methods were used to assess their antioxidant potential. DNA cleavage and protein binding properties of the complexes were monitored through gel electrophoresis and UV‐visible spectrophotometry. The low IC50 value of both complexes implies more potency than the piroxicam. The percent cleavage and binding constant values indicated that the complexes bind with DNA and BSA more efficiently than the piroxicam. In SD rats, complexes were screened for analgesic, anti‐anxiety, anti‐inflammatory, and anti‐hyperglycemic effects. The complexes demonstrated statistically significant results for in‐vivo analysis. Photodegradation results of the metal complexes under UV lamp exhibited abrupt degradation than the piroxicam. Docking results also validate a better propensity of both complexes to bind with DNA and BSA. Hydrogen bonding and Van der Waals forces play a key role in stabilizing complexes in DNA and BSA binding pockets. These metal complexes have evident therapeutic potential more than piroxicam and could be promising drugs for relieving pain, anxiety, inflammation, and associated comorbidities with good pharmacodynamic properties.