bluuebunny/crossref_metadata_2025_split huggingface dataset:
COMPETITIVIDADE DA AGROPECUÁRIA BRASILEIRA: UMA ANÁLISE JUSECONÔMICA
Authors: Delgado Joedson de Souza 
Published: December 2022

Este artigo analisa os aspectos juseconômicos da política macroeconômica relativa a competitividade no setor agropecuário brasileiro com base em dados de produção e do mercado agropecuário no período de 2009 a meados de 2014 e 2015. A pesquisa bibliográfica pressupõe que o crescimento setorial e suas políticas macroeconômicas interferem diretamente na vida das pessoas. Analisa-se aspectos dos dados do panorama e representação do agronegócio nas macrorregiões do País incluindo as interferências das exportações no desenvolvimento da economia e geração de empregos formais. Os resultados evidenciam que o País é um dos principais players com a produção de grãos no mercado internacional.
GOBERNABILIDAD Y GOBERNANZA DEL AGUA COMO BIEN COMÚN DE LA NATURALEZA
Authors: VICTORIA Maria Adriana , VICTORIA María Adriana , VICTORIA María Adriana 
Published: December 2022

El agua es un elemento transversal del desarrollo sostenible y en el desafío de erradicar la pobreza. Los recursos hídricos son indispensables para todos los seres vivos y para vivir en armonía y en equilibrio con el planeta y sus ecosistemas, que algunas culturas reconocen como "Madre Tierra". Por ello reviste importancia la implementación de una política pública del agua como bien común (BC) de la naturaleza, la que puede hacerse desde la gobernanza (concepto dinámico), en tanto trata sobre los procesos y mecanismos de interacción entre los actores gubernamentales y no gubernamentales, y la gobernabilidad, que se refiere al estado resultante de la aplicación de estos mecanismos y procesos, como un fin de la administración. De ahí la importancia por plantear un análisis comparativo entre gobernanza y gobernabilidad del agua como BC, a partir de diversas conceptualizaciones. Con ello se pretende orientar la política del agua. No hay un modelo universal de gobernanza o de gobernabilidad, cada sociedad y relaciones institucionales imponen el modelo más adecuado para su funcionamiento, por lo que el debate sobre estos conceptos sigue abierto.
O DESAFIO DA CONCRETIZAÇÃO E EFETIVA PROTEÇÃO DOS DIREITOS FUNDAMENTAIS EM TEMPOS DE CRISE DA PÓS MODERNIDADE
Authors: Amorim Renata Alves 
Published: December 2022

A realidade global contemporânea, seus novos rearranjos sócias, políticos econômicos permitiram novos debates sobre a compreensão da performance do Estado Democrático de Direito, do conteúdo constitucional e da sistemática de proteção de direitos fundamentais, pois embora o princípio da preservação da dignidade da pessoa humana tenha adquirido o status normativo mais significativo já percebido, os desafios da modernidade como o agravamento de desigualdades, de mazelas sociais, e instabilidades econômicas e políticas, acabam por fomentar frustrações sistemáticas quanto às expectativas democráticas frente à realidade social, que geram inquietações relevantes quanto ao desafio da efetiva concretização e proteção dos direitos fundamentais na sociedade. Busca-se portanto, evidenciar a paulatina recepção desses direitos fundamentais no ordenamento jurídico ocidental, sua essencialidade e progressiva positivação como guião emancipatórios em prol do desenvolvimento social, com a finalidade de propor uma releitura paradigmática conforme o posicionamento de Boaventura de Sousa dos Santos e sua interpretação crítica sobre tal problemática, na tentativa de corroborar o papel fundamental tanto do Estado Democrático de Direito como da sociedade civil na renovação do caráter emancipatório do direito.
POLITICAL, LEGAL AND ORGANIZATIONAL TENDENSIES IN THE EXECUTION OF PUNISHMENT IN THE FORM OF IMPRISONMENT IN RELATION TO CONVICTED WOMEN IN POST-SOVIET CORRECTIONAL COLONIES PERIOD
Authors: Вера Александровна Щетнева, 
Published: December 2022

В постсоветский период (с 1991 г.) в уголовно-исполнительной системе России происходили как позитивные, так и негативные изменения. В статье исследуется определенные тенденции, которые сложились в политико-правовом и организационном аспекте в отношении правового положения осужденных женщин, особенностей порядка исполнения наказания в виде лишения свободы в исправительных учреждениях в указанный промежуток времени (более чем 30 лет). Автором в ходе подготовки научной статьи использованы теоретические методы исследования (анализ, синтез, аналогии, индукции, дедукции, обобщения), практические (частные) методы исследования (наблюдение, беседа и интервьюирование, сравнительно-правовой, историко-правовой). В завершение делается вывод о том, что специфику исполнения наказания в исправительных учреждениях в отношении осужденных женщин определяет психофизиологический фактор.
The post-Soviet period (since 1991) for the penal system of Russia is characterized by both positive and negative moments. Under these conditions, the formation and development of the institution of execution of punishment in the form of imprisonment against convicted women in correctional colonies took place. The period of time we are studying (more than 30 years) allows us to trace certain trends that have developed in the political, legal and organizational aspect in relation to the legal status of convicted women, the peculiarities of the procedure for the execution of sentences in the form of imprisonment in correctional institutions. During the preparation of the scientific article, the author used theoretical research methods (analysis, synthesis, analogies, induction, deduction, generalization), practical (private) research methods (observation, conversation and interviewing, comparative legal, historical and legal).
Coopération, autonomie et territoire politique : les Systèmes alimentaires locaux aux États-Unis
Authors: Nasr Clémence 
Published: December 2022

Au sein de la tendance des circuits courts alimentaires, les Systèmes alimentaires locaux (SAL) se distinguent en raison de l’importance attachée à l’échelle locale et à la proximité géographique entre producteurs et consommateurs. Aux États-Unis, ils pointent également la revitalisation de la communauté. La littérature se concentre précisément sur les risques inhérents à cette échelle : idéalisation et, surtout, repli identitaire et sécession par rapport à la société nationale. Si cette analyse est justifiée, elle n’épuise pas la réalité des SAL. Nous voulons montrer, en les considérant depuis le point de vue de la philosophie sociale, que ceux-ci renferment la possibilité que se mettent en place de véritables rapports coopératifs débouchant sur la maîtrise collective du cycle alimentaire. Dès lors, le territoire agri-alimentaire local revêt une dimension politique qui ne relève pas de l’identité, mais bien de l’aspiration à une forme d’autonomie.
La souveraineté alimentaire au cœur des mobilisations décoloniales et anti-capitalistes : le cas de la communauté autochtone Navajo pendant la pandémie de covid-19
Authors: Clément-Picos Eugénie 
Published: December 2022

Cet article analyse l’évolution du rôle des fermier·es Dinés * de la réserve amérindienne Navajo, dans le Sud-ouest des États-Unis. La nation Navajo cristallise les problèmes du sud-ouest du pays : accès à l’eau, à l’alimentation, manque d’emplois, crise climatique et gouvernance. Dans une perspective ethnographique, les différentes formes de violence rencontrées sont analysées à partir des pratiques et discours des fermier·es. Entre négociations et tensions avec les ONG, les autorités tribales et fédérales, les fermier·es doivent combiner un idéal d’autonomie en interdépendance avec les attentes de la communauté Navajo et la réalité économique. Cet article propose un matériau original pour l’examen et la compréhension des luttes environnementales et défis alimentaires pendant la pandémie de covid-19.
La cinquième branche : mythe, réalité, objectif ? Une analyse, deux ans après…
Authors: Ferras Benjamin 
Published: December 2022

La « branche autonomie » a été créé en 2020, au terme de revendications constantes des représentants des personnes âgées et des personnes handicapées. Revenir sur cette revendication et les conséquences des réformes introduites à partir de 2005, à la suite de la création de la Caisse nationale de solidarité pour l’autonomie, est plus que jamais nécessaire. Identifier les chausse-trappes des notions de « branche » et de « risque » permet de cerner la spécificité des prises en charge de ces publics. L’intégration de cette branche en LFSS constitue une avancée souhaitable. Elle n’est cependant en aucun cas un deus ex machina . Au-delà, la question technique et l’approche principielle sont secondaires. Il s’agit avant tout d’apprécier les modalités dans lesquelles, aujourd’hui et demain, nos aînés et nos concitoyens les plus fragiles et frappés par le sort seront protégés et les conditions dans lesquelles ils peuvent accéder à une dignité qui ne manque que quand on ne peut pas ou plus y prétendre. La réflexion propose donc plusieurs jalons pour relever les défis qui s’offrent à nous.
L’exemple des Ehpad, quels besoins, quelle attractivité ?
Authors: Verger Philippe 
Published: December 2022

Les temps modernes connaissent une transformation profonde des lieux et une optimisation des moyens consacrés à l’accompagnement des grands âgés et des personnes en situation de handicap. Au fil des siècles et des décennies, nous sommes passés des « maisons d’hospitalité » tenues par des religieux aux iv e et v e siècles qui accueillaient des « malheureux » et des malades trop âgés, et après plusieurs étapes, aujourd’hui, à des établissements spécialisés avec un bâtimentaire et des technologies adaptées et des personnels professionnalisés. Notre regard se portera plus particulièrement sur les organisations contemporaines des forces vives mises en œuvre pour l’accompagnement et l’hébergement des personnes âgées.
À la fin de l’éclipse, le visage sort de l’ombre
Authors: Fleury Vincent 
Published: December 2022

Le progrès scientifique donne parfois l’impression d’être linéaire, orienté dans le sens d’un accroissement constant de la précision, au fil du travail des chercheurs. Cependant, dans certaines circonstances, des explications alternatives, ou concurrentes, d’un même phénomène se succèdent avec des éclipses et des réapparitions d’idées anciennes. C’est le cas en embryologie où se font concurrence l’approche physique, morphologique, et l’approche biologique ou génétique. Ce ballet conceptuel est lié fondamentalement à une dualité irréductible de l’univers : la multiplicité des phénomènes observés s’explique par un ensemble très réduit de lois, qui expliquent tout, mais pas dans le détail. Ainsi la physique démontre que les visages, par exemple, se rapportent à un visage idéal universel, sans pouvoir prédire aucun visage particulier.
La dimension affective de l’éducation au changement climatique : étude mixte au cycle 3 de l’enseignement primaire français
Authors: Déduit Camille , Polo Claire 
Published: December 2022

Dans le contexte actuel du dérèglement global du climat, l’école ne peut faire l’impasse sur ce changement majeur et ses risques. En France, la rentrée 2020 a donc été caractérisée par un renforcement de l’éducation relative à l’environnement dans les programmes scolaires, plus spécifiquement d’une éducation au changement climatique. Or, une telle éducation comporte une dimension émotionnelle importante ; elle peut générer par exemple de l’anxiété ou de la colère. Nous nous interrogeons donc sur la façon dont l’éducation au changement climatique est appréhendée au plan émotionnel auprès des élèves. Issus d’une double approche qualitative (analyse du cadrage affectif des ressources pour l’enseignement) et quantitative (questionnaire auprès des élèves), les résultats de notre recherche montrent un positionnement paradoxal des supports didactiques, présentant une tonalité émotionnelle certaine, mais sans mention explicite des émotions. Par ailleurs, on retrouve des émotions intenses dans les déclarations des élèves, parfois associées à leur compréhension des phénomènes ou à leur propension à l’action. Nous pointons de possibles effets spécifiques de l’inquiétude ou de la colère, à confirmer dans des travaux futurs.
Chagas’ disease among school students from Chiapas, Mexico
Authors: Guadalupe Vidal-López Dolores , Martha Bucio Torres , Margarita Cabrera Bravo , Elia Torres Gutiérrez , Adelina Schlie-Guzmán María , Adrián Pérez-Vargas , María Salazar-Schettino Paz 
Published: December 2022

Background & objectives:
Chagas disease is a vector-borne life-threatening illness originally confined to the Americas. Seroprevalence studies have been reported in the Mexican state of Chiapas; nevertheless, no clinical/cardiological studies have been conducted to detect underage cases. The aim of the present work was to detect underage cases in the Mexican state of Chiapas.

Methods:
A serological screening by ELISA was conducted on 1556 blood samples from school pupils; seropositiv- ity was confirmed by indirect ELISA and indirect immunofluorescence. Seropositive cases were clinically assessed in a hospital, and electrocardiographic and echocardiographic studies were performed. Descriptive statistics were used for analysis.

Results:
Seropositivity was confirmed in three cases in the population under study (0.19%). Cardiological studies confirmed the presence of alterations associated to Chagasic cardiomyopathy in two of the three patients.

Interpretation & conclusion:
The conditions for an active transmission of T. cruzi infection are met in the rural localities under study. Additionally, the presence of Chagasic cardiomyopathy in underage patients highlights the relevance of an early detection of cases to provide specific treatment at the onset of the infection and to implement epidemiological surveillance as suggested by PAHO/WHO.
Clinical profile and severity of Plasmodium vivax and falciparum malaria in hospitalized children from North India
Authors: Badugu Venkatesh , Gaur Bablu Kumar , Maini Baljeet 
Published: December 2022

Background & objectives:
Malaria is the most common parasitic infection in children and the most common cause of mortality by vector-borne disease in tropical countries. In these endemic countries there is limited published literature on the clinical profile and severity of Plasmodium vivax malaria in children. We highlight the clinical presentations and severity of malaria in children belonging to Uttar Pradesh, North India

Methods:
This observational study was conducted in a tertiary care hospital, in Moradabad, western Uttar Pradesh, India. Children (aged 6 months–18 years) hospitalized from June 2019 to May 2020 with a clinical picture consistent with malaria along with a positive rapid malaria antigen test (RMAT) and/or positive peripheral blood smear for malaria were enrolled. All data about the clinical profile and laboratory features were recorded. Results were analyzed for significance using appropriate statistical tests for continuous and categorical data.

Results:
One hundred children were enrolled in this study; 59 cases had Plasmodium vivax (PV) malaria, 33 cases had Plasmodium falciparum (PF) malaria, and 8 cases had mixed infections (both PV and PF). Among 59 children with P V malaria, 44 (74%) had severe malaria and 15 (26%) had uncomplicated malaria. Severe malarial anaemia (43.2%), followed by jaundice (36.4%), impaired renal function (21.6%), significant bleeding (18.9%), shock (18.9%), and prostration (16.2%), were the main severity parameters of malaria among these hospitalised children. Impaired renal function (P-value = 0.01) and unconsciousness (P-value = 0.02) were more frequent in Plasmodium falciparum cases. Other severity parameters were not significant between the vivax and falciparum species.

Interpretation & conclusion:
We conclude that a significant proportion of severe malaria was caused by Plasmodium vivax in this region, where both species coexist. Plasmodium vivax malaria is no longer the benign entity it was around ten years ago in hospitalised children. Severe malarial anaemia was the most common severity parameter found in both Plasmodium vivax and P. falciparum species. The clinical presentation and a change in the severity parameters in vivax malaria indicate a recent shift in the disease severity from benign to fatal.
Elucidation of the Mechanism of Gualou-Xiebai-Banxia Decoction for the Treatment of Unstable Angina Based on Network Pharmacology and Molecular Docking
Authors: Tan Yu , Chen Li , Qu Hua , Shi Da-Zhuo , Ma Xiao-Juan 
Published: December 2022

Objective:
The aim of this study was to identify the potential pharmacological mechanisms of Gualou-Xiebai-Banxia decoction (GLXBBX) against unstable angina (UA).

Materials and Methods:
The active compounds of GLXBBX were collected from the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform, and their targets were predicted using the SwissTargetPrediction database. The targets associated with UA were obtained from the Online Mendelian Inheritance in Man, GeneCards, and Therapeutic Target Database. Individual targets associated with UA and GLXBBX were cross-checked to identify the targets of GLXBBX involved in the treatment of UA. A protein–protein interaction network was built using the STRING online database. Cytoscape 3.7.2 software was used to screen out hub genes. Additional gene ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analyses were performed using the clusterProfiler package in R.

Results:
A total of 28 bioactive compounds and 320 protein targets of GLXBBX associated with UA were screened out. Enrichment analysis indicated that the therapeutic effect of GLXBBX may be mediated through the PI3K/AKT, MAPK, and HIF-1 signaling pathways. Molecular docking suggested that the active compounds including Vitamin E, cavidine, and baicalein can bind to their protein receptors.

Conclusions:
This research confirmed the multifactorial effects of GLXBBX in the treatment of UA and laid the foundation for the experimental research on GLXBBX.
Factors Related to Seeking Health Services in People with Mental Disorders and Psychological Problems
Authors: Adianti Talia Puspita , Wardani Tusy Novita Dwi , Wulandari Ratna Dwi 
Published: December 2022

ABSTRACT

Introduction:
Mental disorders are the inability to deal with stressors that interfere with social functions. The public health center seeks to improve the social functions of people with mental disorders (PWMDs) and psychological problems (PWPPs) through the integrated healthcare center. This study aimed to determine the effect of the ability to perceive, approachability, and health care needs on selecting health care facilities for PWMDs and PWPP.

Methods:
The research method used was observational with a cross-sectional design. The sampling technique was a multistage sampling technique with a stratified random sampling method. The research sample size was 16 public health centers, and the respondents were 177 families of PWMDs and PWPPs. The independent variables were the ability to perceive, approachability, and the need for health services. The dependent variable was the selection of health services. Data were obtained by the questionnaire and analyzed using the partial least square measurement.

Results:
A total of 59 families of PWMDs and PWPPs were categorized in the middle adulthood. Most of the people were male with mental disorders and psychological problems (63.1%) than the female gender (37.9%). The results of this study showed that the ability to perceive (11.622), approachability (3.903), and the need for health services (9.127) affect the desire for health services.

Conclusion:
The ability to perceive, approachability, and the need for health services significantly affect the desire for health services. Advocacy and health education are the necessary recommendations for handling mental health problems.
Total Leukocyte Count in Rattus norvegicus after Duffy Binding-Like 2β-Plasmodium falciparum Erythrocyte Membrane Protein 1 Recombinant Protein Injection: The way to a Peptide-based Malaria Vaccine Development
Authors: Putri Dwi Ari Santi , Sulistyaningsih Erma , Kusuma Irawan Fajar , Dewi Rosita 
Published: December 2022

ABSTRACT

Introduction:
Severe malaria caused by Plasmodium falciparum is mediated by the P. falciparum erythrocyte membrane protein 1 (PfEMP1). It has a DBL2β domain that specifically binds to the intercellular adhesion molecule-1 (ICAM-1) receptor that lies in endothelial cells of many vital organs and is involved in malaria pathogenesis. Antibody against the DBL2β-PfEMP1 protein correlates with a reduced risk of severe malaria, making it a potential malaria vaccine candidate. This study aimed to examine total leukocytes after serial DBL2β-PfEMP1 recombinant protein injection to determine its immunogenicity. Settings and Design: This was an experimental study using pre-post control groups design.

Methods:
Samples were male rats aged 2-3 months with a weight of 150-350 g. Rats were injected 3x with 100 µg, 150 µg, and 200 µg of the purified DBL2β-PfEMP1 recombinant protein in the three-weeks interval. Blood samples were collected on days 0, 8, 29, and 50, and total leukocytes were counted using the improved Neubauer counting chamber and observed under a microscope. The data were analyzed using the Friedman test, Kruskal Wallis test, and Mann-Whitney test.

Results:
The lowest leukocyte level was at the pre-injection, and the highest level was after the third injection. There was a significant increase in leukocytes (P < 0.05) in all treatment groups but no increase in the control group. A dose of 100 µg of DBL2β-PfEMP1 recombinant protein showed the best response in inducing the increase of total leukocytes.

Conclusion:
The DBL2β-PfEMP1 recombinant protein could induce the higher leukocyte level in each injection, especially after the third injection.
Evaluation of the effect of intravitreal antivascular endothelial growth factor versus medical treatment in acute central serous chorioretinopathy
Authors: Sallam Moataz A. 
Published: December 2022

Objective
To assess the effectiveness of intravitreal ranibizumab or aflibercept versus medical therapy for treatment of patients presented with acute central serous chorioretinopathy.

Patients and method
This comparative controlled clinical trial involved 45 eyes of 45 patients having acute central serous chorioretinopathy. Patients were divided into three equal groups: the first patient group received intravitreal aflibercept, the second one received intravitreal ranibizumab, and the third one, control group, received medical therapy: oral spironolactone 100 mg once daily and topical bromfenac 0.09% q.i.d. All groups were observed over a duration of 6 months and assessed for best-corrected visual acuity (BCVA), pattern on fundus fluorescein angiography, duration of visual recovery, recurrence rate, and possible complications after intravitreal injections. The central macular thickness (CMT), the subfoveal choroidal thickness (CT), the subretinal fluid (SRF), and the foveal vascular density were compared across the groups.

Results
By the end of the follow-up, BCVA significantly (P<0.01) improved in all groups. However, group comparison revealed no significant differences (P>0.05). A significant reduction in the CMT due to resolution of the SRF existed at 2 weeks after treatment in all groups till complete resolution at 6 months. For subfoveal CT, within-group analysis reported nonsignificant (P>0.05) differences in the intravitreal injection groups, whereas a significant (P<0.05) reduction in CT was recorded in the control group at 3 and 6 months. The foveal vascular density showed nonsignificant differences (P<0.05) within and among study groups.

Conclusion
Intravitreal injections had similar effects as medical treatment in improving BCVA, CMT, and SRF but had weaker action on CT.