bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Pesticide Decision Support Tool to guide the selection of less environmentally harmful pesticides for the sugar cane industry
Authors: St. John Warne Michael , Neale Peta A. , Macpherson Michael J. 
Published: September 2023

AbstractPesticides applied to agricultural land have been shown to decrease the quality of water entering the Great Barrier Reef lagoon. This issue is addressed by the Reef 2050 Water Quality Improvement Plan which includes a pesticide reduction target. As part of a wider educational strategy, one method that could help meet the target is to provide stakeholders with information that assists in the selection and use of pesticide active ingredients (PAIs) that pose a lower risk to aquatic environments compared to those currently used. This study developed a Pesticide Decision Support Tool (PDST) in collaboration with stakeholders for the sugar cane industry. The PDST covers all PAIs registered and applied to sugar cane in Australia and four additional PAIs registered for use on crops grown in rotation with sugar cane. The PDST incorporates both the measure of mobility and persistence of a PAI and the measure of effect, which is based on the PAI application rate and ecotoxicity threshold value. The aquatic risk, which is the product of the measure of effect and the measure of mobility and persistence, is a measure of the likelihood that a PAI will reach the aquatic environment and cause harmful effects. Insecticide active ingredients (e.g., cadusafos, chlorpyrifos) posed the greatest aquatic risk, followed by herbicide active ingredients (e.g., MSMA, metolachlor), while fungicide AIs typically had a lower aquatic risk. An interactive spreadsheet allows characteristics, including application rate and tank mixes, to be considered when assessing the potential risk. While focusing on sugar cane, the results are equally appropriate to other crops that use the same PAIs provided the application rates are corrected to the new crop. In addition, the approach used in the PDST can be applied internationally and to any PAIs with sufficient toxicity, mobility, and persistence data.
Functional network disorganization and cognitive decline following fractionated whole-brain radiation in mice
Authors: Seitzman Benjamin A. , Reynoso Francisco J. , Mitchell Timothy J. , Bice Annie R. , Jarang Anmol , Wang Xiaodan , Mpoy Cedric , Strong Lori , Rogers Buck E. , Yuede Carla M. , Rubin Joshua B. , Perkins Stephanie M. , Bauer Adam Q. 
Published: September 2023

AbstractCognitive dysfunction following radiotherapy (RT) is one of the most common complications associated with RT delivered to the brain, but the precise mechanisms behind this dysfunction are not well understood, and to date, there are no preventative measures or effective treatments. To improve patient outcomes, a better understanding of the effects of radiation on the brain’s functional systems is required. Functional magnetic resonance imaging (fMRI) has shown promise in this regard, however, compared to neural activity, hemodynamic measures of brain function are slow and indirect. Understanding how RT acutely and chronically affects functional brain organization requires more direct examination of temporally evolving neural dynamics as they relate to cerebral hemodynamics for bridging with human studies. In order to adequately study the underlying mechanisms of RT-induced cognitive dysfunction, the development of clinically mimetic RT protocols in animal models is needed. To address these challenges, we developed a fractionated whole-brain RT protocol (3Gy/day for 10 days) and applied longitudinal wide field optical imaging (WFOI) of neural and hemodynamic brain activity at 1, 2, and 3 months post RT. At each time point, mice were subject to repeated behavioral testing across a variety of sensorimotor and cognitive domains. Disruptions in cortical neuronal and hemodynamic activity observed 1 month post RT were significantly worsened by 3 months. While broad changes were observed in functional brain organization post RT, brain regions most impacted by RT occurred within those overlapping with the mouse default mode network and other association areas similar to prior reports in human subjects. Further, significant cognitive deficits were observed following tests of novel object investigation and responses to auditory and contextual cues after fear conditioning. Our results fill a much-needed gap in understanding the effects of whole-brain RT on systems level brain organization and how RT affects neuronal versus hemodynamic signaling in the cortex. Having established a clinically-relevant injury model, future studies can examine therapeutic interventions designed to reduce neuroinflammation-based injury following RT. Given the overlap of sequelae that occur following RT with and without chemotherapy, these tools can also be easily incorporated to examine chemotherapy-related cognitive impairment.
Problematic Pornography Use: Can It Be Accurately Measured via the Problematic Pornography Use Scale?
Authors: Zarate Daniel , Allen Andrew , Kannis-Dymand Lee , Karimi Leila , Stavropoulos Vasileios 
Published: September 2023

AbstractPornography use has increased its popularity worldwide, raising concerns about potential disordered use. Considering the lack of recognition in diagnostic manuals, conceptual clarification and the validation of robust instruments assessing this problem are much needed. The current study is aimed at assessing the psychometric properties of the Problematic Pornography Use Scale (PPUS). Exploratory and confirmatory analyses (EFA and CFA) were used to assess a four-factor and a bifactor solution. Additionally, this study used latent profile (LPA) and sensitivity analyses to determine suggested cut-off values to identify at-risk users. A large sample of adult pornography users completed the PPUS online (N = 1149). A four-factor solution as proposed by Kor and colleagues (Addictive Behaviors, 39(5), 861-868, Kor et al., Addictive Behaviors 39:861–868, 2014) was identified as the optimal factorial structure. Participants were classified into five profiles, with 3.9% identified as at-risk users, 19.9% as moderate to high risk. A cut-off value of 33 was suggested to accurately identify at-risk users. The PPUS is a multidimensional instrument, showing good adept ability to detect users at risk of problematic pornography use.
Comparative Study of Numerical Methods for Predicting Wave-Induced Motions and Loads on a Semisubmersible
Authors: Gao Qian , Jiang Changqing , Yang Youjun , Ritschel Uwe 
Published: September 2023

AbstractNumerical simulation tools based on potential-flow theory and/or Morison’s equation are widely used for predicting the hydrodynamic responses of floating offshore wind platforms. In general, these simplified approaches are used for the analysis under operational conditions, albeit with a carefully selected approach to account for viscous effects. Nevertheless, due to the limit hydrodynamic modelling to linear and weakly nonlinear models, these approaches severely underpredict the low-frequency nonlinear wave loads and dynamic responses of a semisubmersible. They may not capture important nonlinearities in severe sea states. For the prediction of wave-induced motions and loads on a semisubmersible, this work systematically compares a fully nonlinear viscous-flow solver and a hybrid model combining the potential-flow theory with Morison-drag loads in steep waves. Results show that when nonlinear phenomena are not dominant, the results obtained by the hybrid model and the high-fidelity method show reasonable agreement, while larger discrepancies occur for highly nonlinear regular waves. Specifically, regular waves with various steepness over different frequencies are focused in the present study, which supplements the understanding in applicability of these two groups of method.
Recommendations for the management of yttrium-90 radioembolization in the treatment of patients with colorectal cancer liver metastases: a multidisciplinary review
Authors: González-Flores Encarna , Zambudio Natalia , Pardo-Moreno Pedro , Gonzalez-Astorga Beatriz , de la Rúa Jorge Roldán , Triviño-Ibáñez Eva M. , Navarro Pablo , Espinoza-Cámac Nataly , Casado Miguel Ángel , Rodríguez-Fernández Antonio 
Published: September 2023

Abstract
Purpose
Strategies for the treatment of liver metastases from colon cancer (lmCRC) are constantly evolving. Radioembolization with yttrium 90 (Y-90 TARE) has made significant advancements in treating liver tumors and is now considered a potential option allowing for future resection. This study reviewed the scientific evidence and developed recommendations for using Y-90 TARE as a treatment strategy for patients with unresectable lmCRC.

Methods
A multidisciplinary scientific committee, consisting of experts in medical oncology, hepatobiliary surgery, radiology, and nuclear medicine, all with extensive experience in treating patients with ImCRC with Y-90 TARE, led this project. The committee established the criteria for conducting a comprehensive literature review on Y-90 TARE in the treatment of lmCRC. The data extraction process involved addressing initial preliminary inquiries, which were consolidated into a final set of questions.

Results
This review offers recommendations for treating patients with lmCRC using Y-90 TARE, addressing four areas covering ten common questions: 1) General issues (multidisciplinary tumor committee, indications for treatment, contraindications); 2) Previous process (predictive biomarkers for patient selection, preintervention tests, published evidence); 3) Procedure (standard procedure); and 4) Post-intervention follow-up (potential toxicity and its management, parameters for evaluation, quality of life).

Conclusions
Based on the insights of the multidisciplinary committee, this document offers a comprehensive overview of the technical aspects involved in the management of Y-90 TARE. It synthesizes recommendations for applying Y-90 TARE across various phases of the treatment process.
Fabrication of sub-20 nm MoS2 horizontal nanowire on silicon substrates by inclusion of precursors into polystyrene-b-polyethylene oxide nanopatterns: Detailed structural investigation
Authors: Ghoshal Tandra , Morris Michael A. 
Published: September 2023

AbstractHerein, we demonstrate the fabrication of sub-20 nm MoS2 horizontal nanowire arrays on silicon substrates using a self-assembled block copolymer assisted in situ inclusion approach. Microphase separated long-range ordered polystyrene-b-polyethylene oxide (PS-b-PEO) block copolymer (BCP) line-space nanopatterns were achieved through thermo-solvent annealing. The patterns produced had long-range order and domain sizes > 1 µm. The BCP structures were lightly etched and modified by anhydrous ethanol to facilitate insertion of molybdenum precursor within the film maintaining the parent BCP arrangements. Horizontal ordered molybdenum oxide nanowire arrays were then fabricated by ultraviolet (UV)/ozone treatment at room temperature. The oxides were converted to sulphides by thermal evaporation at different temperatures in Ar/H2 environment. X-ray photoelectron spectroscopy revealed the composition and phases of the molybdenum oxide and sulphide nanowires. Elemental mapping was performed to investigate the interfaces between the oxide and sulphide nanowires with the substrate surface. The formation and stability of the sulphide nanowires were studied at different temperatures. The photoluminescence and Raman properties were studied at different formation temperatures to investigate defects and estimate the number of layers.
Personality Enhanced Emotion Generation Modeling for Dialogue Systems
Authors: Ma Zhiqiang , Jia Wenchao , Zhou Yutong , Xu Biqi , Liu Zhiqiang , Wu Zhuoyi 
Published: September 2023

AbstractEmotion plays a crucial role in human communication, as it adds depth and richness to conversations. In recent years, there has been growing interest in developing conversation systems with the ability to generate emotions. However, to create more engaging and realistic interactions, it is essential to consider the influence of personality on emotion generation. This paper proposes a novel approach that combines personality modeling with emotion generation for conversation systems. By incorporating personality traits into the emotion generation process, we aim to create more personalized and contextually appropriate emotional responses. Drawing from BigFive model and emotion computation techniques, our model takes into account individual differences in personality to generate emotions that align with each user’s unique characteristics. Experiments show that combining emotion modeling with personality in a dialogue system helps improve the performance of emotion generation models. Additionally, it is also verified that our approach outperforms other baselines on several metrics.
Reliable measurement methods for the isovolumic relaxation time: comparisons of dual gate Doppler and seven other methods
Authors: Kimura Noriko , Toide Hiroyuki , Kobayashi Sayuki , Tsujimoto Emi , Honda Asuka , Sawada Kenta , Higashi Ayako , Koshikawa Yuri , Hana Shinsei , Itabashi Yuji 
Published: September 2023

Abstract
Purpose
Isovolumic relaxation time (IVRT) is a useful indicator of diastolic dysfunction. However, a measurement method for IVRT has not been established. The Dual Gate Doppler method, which can record two separate pulse-wave Doppler signals simultaneously using two sample gates, may be ideal for measuring IVRT. This study aimed to evaluate the accuracy of IVRT measured using conventional methods versus that measured using the Dual Gate Doppler method.

Methods
A total of 104 patients (mean age 58 ± 21 years, 48 women) were examined using ultrasound equipment with Dual Gate Doppler at our hospital. In addition to Dual Gate Doppler method, IVRTs were measured using seven different methods: pulsed Doppler (PW method), continuous wave Doppler (CW method), and other methods. The IVRT values obtained using the Dual Gate Doppler method were compared with those measured using other methods.

Results
All IVRTs measured using conventional methods showed a strong correlation with the that measured using the Dual Gate Doppler method. However, there were slight deifferences among the IVRTs depending on the method. The PW method and the PW time difference method using only the PW showed small statistical bias and were not complicated. The IVRT measured using the CW method was significantly longer than that measured using the Dual Gate Doppler method.

Conclusions
Among the conventional methods, the PW method was the simplest and most practical method for measuring the IVRT in any conditions as arrhythmias. It is important to recognize the characteristics of IVRTs based on the measurement method.
Body Checking in Anorexia Nervosa: from Inquiry to Habit
Authors: Steglich-Petersen Asbjørn , Varga Somogy 
Published: September 2023

AbstractBody checking, characterized by the repeated visual or physical inspection of particular parts of one’s own body (e.g. thighs, waist, or upper arms) is one of the most prominent behaviors associated with eating disorders, particularly Anorexia Nervosa (AN). In this paper, we explore the explanatory potential of the Recalcitrant Fear Model of AN (RFM) in relation to body checking. We argue that RFM, when combined with certain plausible auxiliary hypotheses about the cognitive and epistemic roles of emotions, is able to explain key characteristics of body checking, including how body checking behavior becomes habitual and compulsive.
Sensorless motor control for electro-mechanical flight control actuators
Authors: Kowalski Robert , Juchmann Patrick 
Published: September 2023

AbstractElectro-mechanical flight control actuators have become a viable option as a replacement for conventional hydraulic actuators in future more electric aircraft. A rotor angle measurement is generally required for field-oriented control of the electrical machine and usually obtained from a safety-critical resolver. It contributes, however, to a rising local hardware complexity with a negative impact on space allocation, weight, motor inertia, reliability, and cost. This paper investigates sensorless control strategies that might substitute the resolver with an accurate estimate value. A hybrid observer is implemented that allows position control without an angle sensor at all speeds. In the high speed domain, the extended electromotive force of the permanent magnet synchronous machine is used for angle estimation. In the low speed domain, including standstill, anisotropy properties of the motor are exploited by applying the alternating injection method. The performance of the control algorithm is evaluated on an aileron actuator test rig for a large civil aircraft.
Hemoglobin A1c Serum Level Predicts 5-year Mortality in Patients with Cognitive Impairment
Authors: Dreier J. , Schernhammer E. , Haslacher H. , Stögmann E. , Lehrner J. 
Published: September 2023

Abstract
Background
Subjective cognitive decline (SCD) and mild cognitive impairment (MCI) may occur as preclinical stages of Alzheimer's disease (AD), ultimately leading to dementia. Glycated hemoglobin A1c (HbA1c) is a diagnostic marker for diabetes mellitus and indicates mortality risk.

Objectives
This university-based, exploratory retrospective study examined the impact of HbA1c serum level on 5-year mortality among individuals with cognitive impairment.

Methods
Included were 1076 subjects aged at least 50 years who visited the Memory Outpatient Clinic of the Medical University of Vienna due to memory problems. Participants were diagnosed with SCD, MCI, or AD subsequent to neurological examination, standard laboratory blood tests, and neuropsychological testing. Survival was compared between diagnostic subgroups and with respect to HbA1c categories using log-rank tests based on Kaplan–Meier functions. The Neuropsychological Test Battery Vienna (NTBV) was dimensionally reduced, and a principal component analysis (PCA) was performed to further analyze results. Corresponding factor scores, HbA1c values, and baseline characteristics were included in Cox proportional hazards models to assess 5-year mortality risk.

Results
During the observation period, 323 patients (30%) died at a mean age comparable between diagnostic subgroups (SCD 84.2 ± 10.1, MCI 81.2 ± 8.3, AD 82.2 ± 7.4 years). Individuals with normal serum HbA1c levels had significant advantages in survival within the MCI (12.9 ± .3 vs. 10.0 ± .8 years) and the AD subgroups (8.2 ± .4 vs. 5.5 ± .6 years), and metric HbA1c predicted 5-year mortality (HR 1.24).

Conclusion
This study demonstrates an association between abnormal HbA1c serum levels and increased mortality.
Oral Health-Related Quality of Life in Celiac Portuguese Children: a cross-sectional study
Authors: Coelho M. , Bernardo M. , Mendes S. 
Published: September 2023

Abstract
Purpose
Celiac Disease (CD) presents a wide variety of clinical signs and symptoms, including oral manifestations. This study pretended to characterize Oral Health-Related Quality of Life (OHRQoL) and reported oral manifestations in children with CD.

Methods
Target-population were children with CD. An online questionnaire, applied to children’s parents, collected information about OHRQoL (using the Early Childhood Oral Health Impact Scale—ECOHIS), oral health behaviours, and history of oral manifestations. Data analysis included descriptive statistics, Mann–Whitney, Kruskall-Wallis, and Spearman correlation tests (α = 0.05).

Results
The sample included 146 celiac patients, with a mean age of 10.5 years (sd = 4.1). Mean ECOHIS score was 5.2 (sd = 6.8). The most frequently reported oral manifestations were recurrent aphthous stomatitis (46.6%), dental caries (45.2%) and dental opacity (39%). About one third of the participants mentioned improvements in oral health when a gluten-free diet was introduced. Most of the reported oral manifestations had a significant association with the ECOHIS score (p < 0.05).

Conclusions
The OHRQoL of children was good, however oral manifestations had a negative impact on OHRQoL. The most reported oral manifestations were recurrent aphthous stomatitis, dental caries, and dental opacities. Oral health professionals must be aware about the heterogeneity of the disease, to recognize oral manifestations associated and their importance in the early diagnosis to reduce complications and to an improvement in the OHRQoL of these patients.
Marketing at UNSW Sydney: Building Marketing Capability in Australasia
Authors: Roberts John H. , Uncles Mark , van Heerde Harald J. , Melnyk Valentyna , Dong Maggie Chuoyan 
Published: September 2023

AbstractThis paper traces the evolution of the marketing discipline within the University of New South Wales (UNSW) Sydney, the home of Australasia’s pioneering university-based marketing school. It contrasts how marketing has evolved in Australasia compared to North American and European schools. The early emphasis on industry engagement and practice and specialized education and research have given UNSW Sydney a number of advantages which it has leveraged through its education programs and impactful research. After detailing the development of the discipline of Marketing within UNSW and providing examples of where it has contributed to marketing thought and practice, the paper looks to the future, outlining how the School is moving forward.
Peritoneal dialysis discontinuation: to the root of the problem
Authors: Piarulli Paola , Vizzardi Valerio , Alberici Federico , Riva Hilary , Aramini Marta , Regusci Luca , Cippà Pietro , Bellasi Antonio 
Published: September 2023

AbstractAs the global burden of chronic kidney disease continues to increase, the use of peritoneal dialysis is often advocated as the preferred initial dialysis modality. Observational studies suggest a survival advantage for peritoneal dialysis over hemodialysis for the initial 2–3 years of dialysis. Peritoneal dialysis has been associated with better graft survival after kidney transplantation and has a reduced cost burden compared to hemodialysis. However, several medical and non-medical reasons may limit access to peritoneal dialysis, and less than 20% of patients with end-stage kidney disease are treated with peritoneal dialysis worldwide. In this narrative review, we sought to summarize the recent medical literature on risk factors for peritoneal dialysis discontinuation, distinguishing the early and the late phase after peritoneal dialysis initiation. Although the definition of clinically relevant outcomes varies among studies, we observed that center size, older age, and the presence of many comorbidities are risk factors associated with peritoneal dialysis discontinuation, regardless of the phase after peritoneal dialysis initiation. On the contrary, poor technique training and late referral to nephrology care, as opposed to the need for a caregiver, patient burnout and frequent hospitalizations, are related to early and late peritoneal dialysis drop-out, respectively. The aim of the review is to provide an overview of the most relevant parameters to be considered when advising patients in the selection of the most appropriate dialysis modality and in the clinical management of peritoneal dialysis patients. In addition, we wish to provide the readers with a critical appraisal of current literature and a call for a consensus on the definition of clinically relevant outcomes in peritoneal dialysis to better address patients' needs.
Graphical abstract