bluuebunny/crossref_metadata_2025_split huggingface dataset:
Girls and Boys Typically Have Similar Math Value Beliefs: Replication Evidence Across Historical Time, High School, and Racial/Ethnic Groups
Authors: Starr Christine R. , Lee‐Poon Glona , Rubach Charlott , Gao Yannan , Safavian Nayssan , Dicke Anna‐Lena , Eccles Jacquelynne S. , Simpkins Sandra D. 
Published: January 2025

ABSTRACTIntroductionIndividuals' math value beliefs are theorized to influence who persists in STEM. However, the existing findings on gender differences in adolescents' math value beliefs are inconsistent. The goal of this study was to use three existing datasets to help clarify when gender differences emerge for high school adolescents and for whom (i.e., adolescents across historical time, grade level, and race/ethnicity). Specifically, we examined the extent to which gender differences in adolescents' math value beliefs (i.e., interest, utility, and attainment) replicated (1) across three datasets spanning the 1990s to 2010s, (2) from 9th–12th grade, and (3) within each of the four largest U.S. racial/ethnic groups (i.e., Asian, Black, Latine, and White adolescents).MethodsWe tested these aims with three existing longitudinal U.S. datasets: the California Achievement Motivation Project (CAMP) (n = 8855), the Childhood and Beyond Study (CAB) (n = 582), and the High School Longitudinal Study (HSLS) (n = 21,000). Students were in high school (9th–12th grade) and half were girls (49%–53%). All three datasets included measures with the same or similar math value belief items, making conceptual replication possible.Results and ConclusionsOverall, we did not find strong evidence for meaningful gender differences in adolescents' math value beliefs overall. We did find meaningful gender differences in the oldest data set (CAB). When examined within each racial/ethnic group, we found no evidence of gender differences in math value beliefs among Black or Latine adolescents, but some differences among Asian and White adolescents. The findings align with the gender similarities hypothesis, suggesting adolescent girls and boys had similar math value beliefs.
The Role of Perceived Neighborhood Factors and the Built Environment on Depression and Stress Among Latinas on US‐Mexico Border
Authors: Petruzzi Liana J. , Errisuriz Vanessa L. , Valdez Carmen R. , Parra‐Medina Deborah 
Published: January 2025

ABSTRACTNeighborhood factors and the built environment (e.g., sidewalks, bike lanes and public transportation) are important social determinants of mental health. Yet scarce research explores their impact on Latinx mental health in Colonias (unincorporated, rural communities with limited access to basic utilities like water and electricity) along the U.S.‐Mexico border. Secondary analysis of baseline data from a promotora‐led, physical activity intervention in Colonias examined relationships between neighborhood environment and mental health among Spanish‐speaking Latinas (N = 620) mostly born in Mexico (86%). The Physical Activity Neighborhood Environment Scale (PANES) assesses the perceived neighborhood environment such as neighborhood safety, infrastructure, and access to destinations. Multivariate linear regressions assessed associations between the PANES, the Built Environment Index (BEI), stress (PSS‐10) and depression (CESD‐10), controlling for age, marital status, education, income, and nativity. Most participants (90%) reported moderate to high stress (PSS ≥ 14), and approximately 30% were at risk for clinical depression (CESD ≥ 10). Analyses indicated that higher PANES total scores were significantly associated with lower depression (β = −0.88, p < 0.05) and stress (β = −1.67, p < 0.001). Similarly, higher BEI total scores were significantly associated with lower stress (β = −0.53, p < 0.001). Individual BEI items, including greater housing density (β = −1.26) and neighborhood access to recreation facilities (β = −0.97), were significantly associated with lower depression scores (p < 0.05). The built environment had a significant impact on mental health among Latinas residing in Colonias. Neighborhood density and access to recreation facilities were particularly important, potentially serving as protective factors for mental health. Investment in the built environment in Colonias could improve mental health.
Link between children's oppositional behaviors and parental quality of life post‐ASD diagnosis: Mediating role of parental stress and coping strategies
Authors: Rattaz Cécile , Pickles Andrew , Vernhet Christelle , Michelon Cécile , Picot Marie‐Christine , Baghdadli Amaria 
Published: January 2025

AbstractBackgroundOppositional behaviors are often an important issue for parents who have a child with autism spectrum disorder (ASD), and have been shown to be related to their Quality of Life (QoL). The present study examines the possible mediation and moderation effects of parenting stress and coping in the relationship between oppositional behaviors in the child with ASD and parental QoL.MethodParental stress, coping strategies, parental QoL and children's challenging behaviors (CBCL oppositional problem domain) were studied through parent‐report (335 mothers and 230 fathers) over two occasions in a cohort of 485 children and adolescents with ASD (398 boys and 87 girls) with a mean age of 6.14 years (SD = 3.46) at baseline. Mediation and moderation effects were examined using structural equation modeling.ResultsStrong associations between child behaviors, parental stress and parental QoL were evidenced. Parental stress mediated the relationship between opposition in the child and parental QoL at diagnosis, but this effect was much smaller 3 years after diagnosis. Surprisingly, problem solving and social support, two commonly recommended coping strategies, had little or no effect on reducing impact on QoL 3 years later.ConclusionsLongitudinal analysis allowed us to estimate the causal pathway between child oppositional behaviors, parental stress and impact on parental QoL. Our findings emphasize the crucial role of parental stress, which can mediate the impact of the children's oppositional behaviors on parental QoL. They argue for the need to develop specific interventions for parents focusing on parental stress and child's behavior management.
Anxiety, mental suffering, and bruxism in dental students in the COVID‐19 postpandemic moment
Authors: Perosso Bruna , da Silva Patrícia , Kinalski Mateus de Azevedo , Adalberto Rodrigues‐Junior Sinval 
Published: January 2025

AbstractObjectivesThe COVID‐19 pandemic was devastating, causing deaths, economic and social problems, and mental disorders in the lives of many people. After 3 years, the mental repercussions caused by the pandemic are unclear, especially in young adults. This study assessed the occurrence of mental disorders, anxiety, and bruxism in dental students during the postpandemic moment and determined the factors that influenced the occurrence of bruxism.MethodsThe cross‐sectional study enrolled 126 dental students. Sociodemographic information, COVID‐19 experience, and remote teaching/learning were collected using questionnaires. Mental state and disorders were collected using the State‐Trait Anxiety Inventory (STAI‐T) and the Self‐Reporting Questionnaire‐20 (SRQ‐20) of mental disorders. Bruxism was self‐reported. Data were analyzed using chi‐square test, bivariate and multivariate logistic regression (α = 0.05).ResultsModerate anxiety manifested in 62.7% of the students. Common mental disorders and bruxism were identified in 35.7% and 59.5% of the students. The odds ratio for bruxism self‐report was 6.44 (95% confidence interval [CI] 2.49–16.66) times higher for those who suffered economic impact during the pandemic and 2.39 (95% CI 1.04–5.47) times higher for those reporting anxiety during the pandemic. Bad sleep was also associated with the occurrence of bruxism.ConclusionIn the postpandemic period, dental students exhibited high rates of common mental disorders, anxiety, and bruxism. The increased occurrence of bruxism was linked to the economic impacts experienced during the pandemic, self‐perceived anxiety during the pandemic, and poor sleep.
Trend of Representation of Women in Gastroenterology, Hepatology, and Endoscopy Conferences in Asia
Authors: Devi Jalpa , Chantarojanasiri Tanyaporn , Hang Dao Viet , Lui Rashid , Ali Raja Affendi Raja , Butt Amna Subhan , Raja Rohan , To Tram Trinh , Chan Ting Ting ,   Women in GI Focus Group, Emerging Leaders Committee, Asian Pacific Association of Gastroenterology
Published: January 2025

ABSTRACTObjectivesDespite progress in promoting gender equality, gender bias remains a significant obstacle for women and hinders their academic advancement. We aim to survey and critically analyze women's representation in conferences and changes over time in various regions of Asian countries.MethodsAn international survey was conducted with representatives from East Asia (Hong Kong, China, and Japan), South Asia (India and Pakistan), and Southeast Asia (Vietnam and Thailand). The survey collected data on faculty members serving as chairpersons, moderators, speakers, and organizing committee members of annual scientific meetings held between 2018 and 2022.ResultsA total of 33 conferences were held between 2018 and 2022: 24 in gastroenterology, 5 in hepatology, and 4 in endoscopy across East, South, and Southeast Asia, respectively. The total number of invited faculty members was 4106. Out of 4106, the number of women involved as chairperson, moderator, speakers, and organizing committee was 105, 78, 290, and 146, respectively. The representation of women faculty ranged from 3.8% to 25% in East Asia, 9.2% to 13.5% in South Asia, and 11.8% to 34.3% in Southeast Asia. Overall, the increase in women's participation was minor and statistically non‐significant. However, there was an increase of women's participation as chairpersons, moderators, speakers, and organizing committee members from 14.1% in 2018 to 15.2% in 2022.ConclusionParticipation of women in Asian annual conferences in the capacity of chairperson, moderator, speaker, and/or organizing committee member was significantly under‐represented. This under‐representation necessitates targeted measures to enhance women's roles in these meetings, thereby supporting their career advancement.
Questionnaire on the surgical indications for intrahepatic cholangiocarcinoma administered to Japanese board‐certified expert hepatobiliary and pancreatic surgeons and instructors
Authors: Kuroda Shintaro , Kobayashi Tsuyoshi , Hatano Etsuro , Kubo Shoji , Endo Itaru , Ohdan Hideki ,   JSHBPS2024‐ICC survey consortium
Published: January 2025

AbstractBackgroundTreatment of intrahepatic cholangiocarcinoma (ICC) remains challenging owing to the lack of clear guidelines on surgical resection. The 2021 ICC guidelines have not fully resolved the ongoing debate between surgical and nonsurgical treatment options. This study aimed to identify trends and issues in ICC treatment strategies in the clinical field by surveying the attitudes of hepatobiliary and pancreatic (HBP) surgeons.MethodsA survey was conducted among 235 board‐certified HBP surgeons affiliated with the Japanese Society of Hepato‐Biliary‐Pancreatic Surgery. This survey explored the perspectives on tumor conditions that define resectable, borderline resectable, and unresectable diseases, focusing on tumor size, number, and vascular invasion.ResultsNotable variability was observed in the criteria for oncological resectability. While 42.1% of the respondents considered a maximum tumor diameter of 5 cm as resectable, 37.5% indicated no size limit for resectability. Opinions regarding the resectability of tumors with lymph node involvement and vascular invasion vary widely, highlighting the need for standardized criteria.ConclusionThis survey revealed diverse approaches for defining resectability in ICC, emphasizing the necessity for more precise guidelines. Further research and expert consensus are required to establish standardized criteria that can guide clinical decision‐making and improve patient outcomes.
How Does Earmarked Foreign Aid Affect Recipient‐Country Ownership?
Authors: Reinsberg Bernhard , Taggart Jack 
Published: January 2025

ABSTRACTHow does earmarked foreign aid affect country ownership, a central principle of the aid effectiveness agenda? Although earmarking was initially purported to reduce donor fragmentation and enhance aid effectiveness, recent evidence suggests that it may undermine ownership. Despite formal commitments to ownership by multilateral institutions and bilateral donors within the Development Assistance Committee (DAC), earmarking potentially strengthens the responsiveness and accountability of international organizations to donors, thereby undermining recipient countries' ownership in formulating policy objectives, use of country‐led results frameworks, and implementation of aid through national systems. We test this expectation through a mixed‐methods approach. We first employ latent factor analysis on new data from two monitoring rounds of the Global Partnership for Effective Development Cooperation, covering 80 donors and 92 recipient countries, to measure ownership by the degree of donor−recipient alignment. Our multivariate regression analysis then demonstrates that earmarked aid significantly reduces recipient‐country ownership. Further examination of institutional and DAC donor policies and discourses reveals limited recognition of the adverse effects of earmarked funding on ownership. We find evidence to support the notion that bilateral donors employ earmarking to both enhance their influence within international development organizations and to pursue national interests, inadvertently sidelining ‘old’ concerns about aid effectiveness and ownership. Our findings thus expose a clear disconnect between donor rhetoric and practice, with significant implications for aid effectiveness and aid allocation more broadly.
Severe neonatal hypotonia due to SLC30A5 variant affecting function of ZnT5 zinc transporter
Authors: Dolgin Vadim , Chabosseau Pauline , Bistritzer Jacob , Noyman Iris , Staretz‐Chacham Orna , Wormser Ohad , Hadar Noam , Eskin‐Schwartz Marina , Kanengisser‐Pines Bibi , Narkis Ginat , Abramsky Ramy , Shany Eilon , Rutter Guy A. , Marks Kyla , Birk Ohad S. 
Published: January 2025

AbstractThe tightly‐regulated spatial and temporal distribution of zinc ion concentrations within cellular compartments is controlled by two groups of Zn2+ transporters: the 14‐member ZIP/SLC39 family, facilitating Zn2+ influx into the cytoplasm from the extracellular space or intracellular organelles; and the 10‐member ZnT/SLC30 family, mobilizing Zn2+ in the opposite direction. Genetic aberrations in most zinc transporters cause human syndromes. Notably, previous studies demonstrated osteopenia and male‐specific cardiac death in mice lacking the ZnT5/SLC30A5 zinc transporter, and suggested association of two homozygous frameshift SLC30A5 variants with perinatal mortality in humans, due to hydrops fetalis and hypertrophic cardiomyopathy. We set out to decipher the molecular basis of a severe hypotonia syndrome. Combining homozygosity mapping and exome sequencing studies of consanguineous Bedouin kindred, as well as transfection experiments and zinc monitoring in HEK293 cells, we demonstrate that a bi‐allelic in‐frame 3bp deletion variant in SLC30A5, deleting isoleucine within the highly conserved cation efflux domain of the encoded ZnT5, results in lower cytosolic zinc concentrations, causing a syndrome of severe non‐progressive neonatal axial and limb hypotonia with high‐arched palate and respiratory failure. There was no evidence of hydrops fetalis, cardiomyopathy or multi‐organ involvement. Affected infants required nasogastric tube or gastrostomy feeding, suffered from various degrees of respiratory compromise and failure to thrive and died in infancy. Thus, a biallelic variant in SLC30A5 (ZnT5), affecting cytosolic zinc concentrations, causes a severe hypotonia syndrome with respiratory insufficiency and failure to thrive, lethal by 1 year of age.
Vascular and Osteological Morphology of Expanded Digit Tips Suggests Specialization in the Wandering Salamander (Aneides vagrans)
Authors: Brown Christian E. , Goldenberg William P. , Hinds Olivia M. , O'Donnell Mary Kate , Staub Nancy L. 
Published: January 2025

ABSTRACTFor over a century researchers have marveled at the square‐shaped toe tips of several species of climbing salamanders (genus Aneides), speculating about the function of large blood sinuses therein. Wandering salamanders (Aneides vagrans) have been reported to exhibit exquisite locomotor control while climbing, jumping, and gliding high (88 m) within the redwood canopy; however, a detailed investigation of their digital vascular system has yet to be conducted. Here, we describe the vascular and osteological structure of, and blood circulation through, the distal regions of the toes of A. vagrans using histology in tandem with live‐animal videos. Specifically, we sectioned a toe of A. vagrans at 0.90 μm, embedded it in Spurrs resin, and stained the tissue with toluidine blue. An additional three toes were sectioned at 10 μm, embedded in paraffin, and after sectioning and mounting, treated with Verhoeff and Quad stains. For living salamanders, we recorded real‐time videos of blood flowing within individual toes upon a translucent surface oriented both horizontally (0°) and vertically (90°) to simulate both prostrate and vertical clinging scenarios, then analyzed the image sequences using ImageJ. We found that the vascularized toe tips have one large sinus cavity that is divided more proximally into two chambers via a septum, and there are mucous and granular glands in the dorsal and dorsolateral integument of the digit tips. Live‐animal trials revealed variable sinus‐filling both within and between toes, seemingly associated with variable pressure applied to the substrate when standing, stepping, clinging, and climbing. We conclude that A. vagrans, and likely other climbing salamanders, can functionally fill, trap, and drain the blood in their vascularized toe tips to optimize attachment, detachment, and complex arboreal locomotion (e.g., landing after gliding flight). Such an adaptation could provide insights for bioinspired designs.
Computer‐Aided Detection (CADe) and Segmentation Methods for Breast Cancer Using Magnetic Resonance Imaging (MRI)
Authors: Jannatdoust Payam , Valizadeh Parya , Saeedi Nikoo , Valizadeh Gelareh , Salari Hanieh Mobarak , Saligheh Rad Hamidreza , Gity Masoumeh 
Published: January 2025

Breast cancer continues to be a major health concern, and early detection is vital for enhancing survival rates. Magnetic resonance imaging (MRI) is a key tool due to its substantial sensitivity for invasive breast cancers. Computer‐aided detection (CADe) systems enhance the effectiveness of MRI by identifying potential lesions, aiding radiologists in focusing on areas of interest, extracting quantitative features, and integrating with computer‐aided diagnosis (CADx) pipelines. This review aims to provide a comprehensive overview of the current state of CADe systems in breast MRI, focusing on the technical details of pipelines and segmentation models including classical intensity‐based methods, supervised and unsupervised machine learning (ML) approaches, and the latest deep learning (DL) architectures. It highlights recent advancements from traditional algorithms to sophisticated DL models such as U‐Nets, emphasizing CADe implementation of multi‐parametric MRI acquisitions. Despite these advancements, CADe systems face challenges like variable false‐positive and negative rates, complexity in interpreting extensive imaging data, variability in system performance, and lack of large‐scale studies and multicentric models, limiting the generalizability and suitability for clinical implementation. Technical issues, including image artefacts and the need for reproducible and explainable detection algorithms, remain significant hurdles. Future directions emphasize developing more robust and generalizable algorithms, integrating explainable AI to improve transparency and trust among clinicians, developing multi‐purpose AI systems, and incorporating large language models to enhance diagnostic reporting and patient management. Additionally, efforts to standardize and streamline MRI protocols aim to increase accessibility and reduce costs, optimizing the use of CADe systems in clinical practice.Level of EvidenceNATechnical EfficacyStage 2
Dynamic Changes and Trends of SARS‐CoV‐2 Antibodies Induced by Infection and Vaccination Across Multiple Time Points
Authors: Zhang Shihan , Kong Xiaoxiao , Zhen Qian , Wei Ye , Shi Chao , Ding Songning , Chen Liling , Dong Chen , Tian Hua , Li Chuchu , Zhou Lu , Zhang Yazhen , Zhu Fengcai , Hu Jianli , Bao Changjun , Jin Hui , Xu Ke , Zhu Liguo 
Published: January 2025

ABSTRACTAs the COVID‐19 pandemic continues, increasingly complex vaccination and infection histories have made it urgent to investigate the antibody dynamics in populations with hybrid immunity. This study aimed to explore the multi‐time‐point dynamics of SARS‐CoV‐2 IgG antibody levels in a community‐based population in Jiangsu Province, China, following the Omicron BA.5 wave, as well as the long‐term persistence of IgG antibodies nearly 2 years postinfection. A total of 2737 participants across Jiangsu Province were followed up at three different time points over a 6‐month period (December 2022–June 2023). Additionally, a cross‐sectional serological survey was conducted in October 2024, involving 230 participants to assess long‐term antibody persistence. We used generalized additive models to fit antibody dynamics curves, generalized linear mixed models to explore factors influencing antibody levels, and Kaplan‐Meier survival analysis to estimate cumulative seroreversion rates. Our findings revealed that, following the large‐scale Omicron BA.5 infections, over 85% of the population initially exhibited seropositive IgG levels. Older individuals (> 65 years) had significantly lower antibody levels and faster rates of decline compared to younger participants. Booster immunization reduced the risk of seroreversion by 59.79% (95% CI: 29.63%–76.46%), while individuals with multiple infections experienced slower antibody decay. In the cross‐sectional survey conducted 22 months postinfection, the IgG seropositivity rate remained high, exceeding 98%, indicating sustained immunity at the population level. This study provides valuable insights into the dynamics and persistence of IgG antibody levels following large‐scale infection. The results underscore the importance of tailored booster immunization strategies to sustain long‐term immunity, especially in vulnerable groups like the elderly. Additionally, ongoing serological monitoring is essential for assessing population immunity and informing future vaccination strategies.