bluuebunny/crossref_metadata_2025_split huggingface dataset:
Setting a foundation for Indigenous knowledge systems‐guided boreal caribou (tǫdzı) conservation planning in the Western Boreal Region of Canada: A systematic map protocol
Authors: Saturno Jacquelyn , Boeckner Matthew , Haché Samuel , Hodson James , McAuley Emily , McIntire Eliot , Micheletti Tatiane , Polfus Jean , Sliwa Sophie , Teed Trevor , Westwood Alana R. 
Published: February 2023

Abstract

In recent years, researchers have increasingly recognized the need to bridge Western and Indigenous knowledge systems to strengthen research in wildlife conservation. Historically, this arena has not made space for Indigenous knowledge holders to share components of their knowledge systems with agency and to support their own self‐determination as equal partners.

Since time immemorial, Indigenous Peoples have been developing, maintaining and refining their own knowledge systems, based on intimate knowledge and relationships with the lands, airs, and waterways. There remains enormous potential for Western scientists to engage in equitable knowledge exchange and co‐production with Indigenous Peoples. This applies to species such as boreal caribou Rangifer tarandus caribou, known by the Dene name, tǫdzı; which hold ecological value and cultural importance for both Indigenous and non‐Indigenous people in the boreal region of Canada.

To gain an overarching perspective of this species, we will create a systematic literature map that will examine peer‐reviewed and grey literature involving spatial mapping of all species of caribou Rangifer tarandus based on Indigenous knowledge. This map will (a) characterize available data and previously engaged knowledge holders and (b) identify positive experiences that exemplify best practices for knowledge co‐production.

Searches will be conducted in English in selected databases. Search strings will be tested against a collection of benchmark papers of documents previously chosen to determine strings with maximum sensitivity and specificity. Results will be reviewed through the: (1) title and abstract; and (2) full text.

All screening decisions will be recorded in a database, with 10% of full‐text screening decisions validated. Items retained for inclusion in the systematic map will be coded using a list of coding questions. Ten percent of coding outcomes will be validated by a second reviewer.

The systematic map will employ a narrative synthesis approach that will compare retained studies against a list of best practices from the current proposal. It will examine case studies that performed well according to the list and contribute to a repository of previously documented Indigenous knowledge about caribou to support projects involving Indigenous and Western knowledge co‐production.
Acute Exposure to Pyridostigmine Bromide Disrupts Cholinergic Myenteric Neuroimmune Function in Mice
Authors: Collier Claudia A. , Foncerrada Steven , Clevenger Abigail J. , Shetty Ashok , Raghavan Shreya A. 
Published: February 2023

AbstractGulf War Illness (GWI) results from chemical exposure during the Gulf War, with notable impacts on gastrointestinal motility. Due to the limited demographic impacted by this ailment, an in‐depth investigation of the GWI has yielded little regarding the underlying pathophysiological mechanisms. Here, the hypothesis that exposure to pyridostigmine bromide (PB) results in severe enteric neuro‐inflammation, that cascades to disruptions in colonic motility, is tested. The analyses are performed on male C57BL/6 mice that are treated with physiologically similar doses of PB given to GW veterans. When colonic motility is assessed, GWI colons have significantly reduced forces in response to acetylcholine or electrical field stimulation. GWI is also accompanied by high levels of pro‐inflammatory cytokines and chemokines, associated with increased numbers of CD40+ pro‐inflammatory macrophages within the myenteric plexus. Enteric neurons responsible for mediating colonic motility reside within the myenteric plexus, and PB exposure reduced their numbers. Significant smooth muscle hypertrophy is also observed due to increased inflammation. Together, the results show that PB exposure caused functional and anatomical dysfunction, promoting impaired motility within the colon. Achieving a greater understanding of the mechanisms of GWI will allow more refinement in therapeutic options that improve veterans’ quality of life.
Dual‐Atom‐Site Sn‐Cu/C3N4 Photocatalyst Selectively Produces Formaldehyde from CO2 Reduction
Authors: Kim Bupmo , Kwon Dayoung , Baeg Jin‐Ook , Austeria P Muthu , Gu Geun Ho , Lee Jeong‐Hyeon , Jeong Jeehun , Kim Wooyul , Choi Wonyong 
Published: February 2023

AbstractThe solar‐driven catalytic reduction of CO2 to value‐added chemicals is under intensive investigation. The reaction pathway via *OCHO intermediate (involving CO2 adsorbed through O‐binding) usually leads to the two‐electron transfer product of HCOOH. Herein, a single‐atom catalyst with dual‐atom‐sites featuring neighboring Sn(II) and Cu(I) centers embedded in C3N4 framework is developed and characterized, which markedly promotes the production of HCHO via four‐electron transfer through the *OCHO pathway. The optimized catalyst achieves a high HCHO productivity of 259.1 µmol g−1 and a selectivity of 61% after 24 h irradiation, which is ascribed to the synergic role of the neighboring Sn(II)–Cu(I) dual‐atom sites that stabilize the target intermediates for HCHO production. Moreover, adsorbed *HCHO intermediate is detected by in situ Fourier transform infrared spectroscopy (CO stretches at 1637 cm−1). This study provides a unique example that controls the selectivity of the multi‐electron transfer mechanisms of CO2 photoconversion using heteronuclear dual‐atom‐site catalyst to generate an uncommon product (HCHO) of CO2 reduction.
High‐Performance Aqueous Zn2+/Al3+ Electrochromic Batteries based on Niobium Tungsten Oxides
Authors: Wu Cong , Shi Hongsheng , Zhao Lianqi , Chen Xin , Zhang Xinshui , Zhang Chang , Yu Jiameng , Lv Yinjie , Wei Ran , Gao Tianyi , Xie Jin , Yu Yi , Liu Wei 
Published: February 2023

AbstractElectrochromic energy storage devices (EESDs) are incorporating electrochromic and energy storage functions, which can visually display energy storage levels in real‐time to promote the next generation of transparent battery development. However, their performances are still limited for practical applications. Herein, a self‐powered EESD based on complex niobium tungsten oxide is designed using aqueous Zn2+ and hybrid Zn2+/Mn+ (Mn+ = Al3+, Mg2+, and K+) electrolytes. The results reveal that the use of Zn2+/Al3+ hybrid electrolyte achieves superior electrochromic performances including a short self‐coloring time, high optical contrast, and excellent cyclic stability. Furthermore, it is also found that the self‐coloring process is accompanied by a high discharged capacity of niobium tungsten oxide, with high optical modulation in the Zn2+/Al3+ hybrid electrolyte. The detailed mechanism on the performances of EESD using various electrolytes is systematically studied. This work provides a simple and effective strategy for an aqueous and self‐powered EESD with high optical contrast and good cycle stability.
Modular Design of a Polymer‐Bilayer‐Based Mechanically Compliant Worm‐Like Robot
Authors: Muff Livius F. , Mills Austin S. , Riddle Shane , Buclin Véronique , Roulin Anita , Chiel Hillel J. , Quinn Roger D. , Weder Christoph , Daltorio Kathryn A. 
Published: February 2023

AbstractSoft earthworm‐like robots that exhibit mechanical compliance can, in principle, navigate through uneven terrains and constricted spaces that are inaccessible to traditional legged and wheeled robots. However, unlike the biological originals that they mimic, most of the worm‐like robots reported to date contain rigid components that limit their compliance, such as electromotors or pressure‐driven actuation systems. Here, a mechanically compliant worm‐like robot with a fully modular body that is based on soft polymers is reported. The robot is composed of strategically assembled, electrothermally activated polymer bilayer actuators, which are based on a semicrystalline polyurethane with an exceptionally large nonlinear thermal expansion coefficient. The segments are designed on the basis of a modified Timoshenko model, and finite element analysis simulation is used to describe their performance. Upon electrical activation of the segments with basic waveform patterns, the robot can move through repeatable peristaltic locomotion on exceptionally slippery or sticky surfaces and it can be oriented in any direction. The soft body enables the robot to wriggle through openings and tunnels that are much smaller than its cross‐section.
Rendering Polyurethane Hydrophilic for Efficient Cellulose Reinforcement in Melt‐Spun Nanocomposite Fibers
Authors: Redondo Alexandre , Bast Livia K. , Djeghdi Kenza , Airoldi Martino , Jang Daseul , Korley LaShanda T. J. , Steiner Ullrich , Bruns Nico , Gunkel Ilja 
Published: February 2023

AbstractMany commodity plastics, such as thermoplastic polyurethanes (PUs), require reinforcement for use as commercial products. Cellulose nanocrystals (CNCs) offer a “green” and scalable approach to polymer reinforcement as they are exceptionally stiff, recyclable, and abundant. Unfortunately, achieving efficient CNC reinforcement of PUs with industrial melt processing techniques is difficult, mostly due to the incompatibility of the hydrophobic PU with hydrophilic CNCs, limiting their dispersion. Here, a hydrophilic PU is synthesized to achieve strong reinforcement in melt‐processed nanocomposite fibers using filter paper‐sourced CNCs. The melt‐spun fibers, exhibiting smooth surfaces even at high CNC loading (up to 25 wt%) indicating good CNC dispersion, are bench‐marked against solvent‐cast films—solvent processing is not scalable but disperses CNCs well and produces strong CNC reinforcement. Mechanical analysis shows the CNC addition stiffens both nanocomposite films and fibers. The stress and strain at break, however, are not significantly affected in films, whereas adding CNCs to fibers increases the stress‐at‐break while reducing the strain‐at‐break. Compared to earlier studies employing a hydrophobic (and stiffer) PU, CNC addition to a hydrophilic PU substantially increases the fiber stiffness and strength. This work therefore suggests that rendering thermoplastics more hydrophilic might pave the way for “greener” polymer composite products using CNCs.
Smooth and Compact All‐Inorganic Perovskite Based Heterojunction Films Enabled by Nanocomposite‐Buffered Thermal Imprint for Highly Sensitive X‐Ray Detection
Authors: Li Liqi , Li Yuyang , Li Jiawen , Fang Yanjun , Yang Deren 
Published: February 2023

AbstractChemical vapor deposition (CVD) is a promising way to fabricate perovskite polycrystalline films for optoelectronic device applications. However, it remains challenging to prepare thick yet smooth and compact all‐inorganic perovskite films by this method, which is of paramount importance for efficient X‐ray detection. In this work, a nanocomposite‐buffered thermal imprint strategy is proposed to improve the surface roughness and eliminate pinholes in CVD‐processed cesium‐lead‐bromide perovskite films with thickness above 40 µm, which is realized by spray‐coating a soft layer composed of organic semiconductors and perovskite quantum dots on top of the perovskite layer and then perform the thermal imprint to prepare the heterojunction films. It is demonstrated that the thermal imprint process can reduce the dark current and noise, enhance the carrier transport properties, as well as improve the spatial uniformity of the devices. Consequently, the optimal detectors show a large sensitivity up to 2 × 104 µC Gyair−1 cm−2 and a very low detection limit of 15 nGyair s−1 that represents one of the most sensitive polycrystalline perovskite X‐ray detectors to date, which highlights the great potential of thermal‐imprinted heterojunction films for realizing high performance X‐ray detection and imaging.
Highly Sensitive and Stable Self‐Powered UV Photodetector Based on Amorphous ZnGa2O4/NiO Type‐II p–n Heterojunction via Low‐Temperature and Band Alignment
Authors: Ling Kang , Li Kuangkuang , Zhang Wanli , Liu Xingzhao 
Published: February 2023

AbstractAn effective p–n heterojunction fabrication strategy of amorphous ZnGa2O4/NiO self‐powered ultraviolet (UV) photodetector is reported to consider both the low‐temperature and band alignment. Owing to the excellent photovoltaic effect, the device exhibits an ultralow dark current of 1.81 pA, a satisfactory response sensitivity of 48.19 mA W−1, a specific detectivity of 1.9 × 1012 Jones, and a high rise/decay speed of 41/22 ms under 255 nm light irradiation at 0 V bias. Compared with previously reported UV photodetectors, the proposed photodetector exhibits a high responsivity of 1.88 A W−1 and an excellent detectivity of 7.1 × 1013 Jones under an applied voltage of −5 V, indicating its ability to detect weak signals. This remarkable photoelectric detection capability is attributed to the strong absorption of UV light by the amorphous ZnGa2O4 and typical type‐II band alignment at the heterojunctions. Moreover, the photodetector continues to function stably without degradation, even after two months without an external power supply. This work not only provides an effective reference for the manufacture of high performance ZnGa2O4‐based UV photodetectors, but also offers the opportunity for practical industrial production and flexible applications.
Deep‐Learning Assisted Polarization Holograms
Authors: Xi Jiawei , Shen Jian , Chow Man To , Li Tan , Ng Jack , Li Jensen 
Published: February 2023

AbstractMultiplexing holography with metasurfaces using different degrees of freedom of light has enabled recent applications in display and information processing. In terms of polarization‐multiplexed holograms, the most general form is an arbitrary Jones matrix profile in storing the maximum amount of information. It requires a relaxation to bianisotropic metasurfaces from a conventional single‐layer implementation of nanostructures, but it will also complicate both the inverse design of the nanostructures and the hologram generation algorithm. Here, an integrated neural network approach, being extended from the recent DeepCGH algorithm, is developed to obtain metasurface structural profiles directly from independent holograms from an arbitrary set of polarizations to another, with maximally four different co‐ and cross‐polarization conversion channels. Such an information‐driven approach enables designing complex polarization holograms directly from an existing metamaterial library without detailed physical knowledge on the constraints, and can be extended to other multiplexing holograms to further facilitate an efficient usage of the information stored on a metasurface.
Bright and Photostable TADF‐Emitting Zirconium(IV) Pyridinedipyrrolide Complexes: Efficient Dyes for Decay Time‐Based Temperature Sensing and Imaging
Authors: Russegger Andreas , Debruyne Angela C. , Berrio Daniel Carvajal , Fuchs Stefanie , Marzi Julia , Schenke‐Layland Katja , Dmitriev Ruslan I. , Borisov Sergey M. 
Published: February 2023

AbstractLuminescence thermometry represents a technique of choice for measurements in small objects and imaging of temperature distribution. However, most state‐of‐the‐art luminescent probes are limited in spectral characteristics, brightness, photostability, and sensitivity. Molecular thermometers of the new generation utilizing air and moisture‐stable zirconium(IV) pyridinedipyrrolide complexes can address all these limitations. The dyes emit pure thermally activated delayed fluorescence without any prompt fluorescence and show a unique combination of attractive features: a) visible light excitation and emission in the orange/red region, b) high luminescence brightness (quantum yields ≈0.5 in toluene and 0.8–1.0 in polystyrene matrix), c) excellent photostability, d) suitability for two‐photon excitation and e) mono‐exponential decay on the order of tens to hundreds of microseconds with strongly temperature‐dependent lifetimes (between −2.5 and −2.9% K−1 in polystyrene at 25 °C). Immobilization in gas‐blocking polymers yields sensing materials for self‐referenced decay time read‐out that are manufactured in two common formats: planar optodes and water‐dispersible nanoparticles. Positively charged nanoparticles are demonstrated to be suitable for nanothermometry in live cells and multicellular spheroids. Negatively charged nanoparticles represent advanced analytical tools for imaging temperature gradients in samples of small volumes such as microfluidic devices.
Stable CsPbX3 (X = Cl, Br, I) Nanocrystal‐in‐Glass Composite (NGC) for Solid‐State Laser‐Driven White Light Generation
Authors: Li Guozhen , Pan Qiwen , Zhou Zhihao , Gu Ranran , Zhang Hao , Huang Xiongjian , Dong Guoping , Xiao Xiudi 
Published: February 2023

AbstractPerovskite CsPbX3 (X = Cl, Br, I) nanocrystals with advantages of high quantum yield, narrow emission peaks, and tunable fluorescence are considered as the next generation of light‐emitting sources. However, fluorescence degradation due to the poor stability of perovskite nanocrystals in moisture, high temperature, and illumination remains one of the greatest challenges in their further development. In this work, a fully dense coating strategy is proposed to improve the overall stability of perovskite nanocrystals, especially under high‐density laser irradiation. A mesoporous silica SiO2 layer is introduced to construct a stable coating for isolating the perovskite from external environment. To eliminate the pores of the CsPbX3@SiO2, an inorganic glass is also employed via solution‐combustion technique to generate a fully compact encapsulation for further stability promotion. The as‐prepared nanocrystal‐in‐glass composite exhibits efficient and stable fluorescence performance in luminous efficiency, chromaticity, and long‐term reliability in the conditions of thermal shock, humidity, and blue laser irradiation. With the integration of red/green/blue emitting nanocrystals, the color gamut of the white laser lighting source covers 134% of the National Television Standards Committee standard, providing exciting opportunity for high performance laser‐driven white light generation.
DBFN: Double Branch Fusion Network for Vital Components and Defect Detection of Transmission Line
Authors: Xu Wenxiao , Chu Shengguang , Yang Shanshan 
Published: February 2023

AbstractA double branch fusion network is proposed based on unmanned aerial vehicle (UAV) inspection images to increase the detection accuracy of vital components and defects in transmission lines. The backbone feature extraction network comprises a combination of a convolutional neural network (CNN) and a Transformer network. To be specific, the CNN should extract local information, and the Transformer network is responsible for the extraction of global information. Besides, global information and local information have semantic differences, while resulting in feature aliasing after fusion. To solve this problem, a multiscale convolution module and a multiscale pooling module are proposed to solve semantic differences and feature aliasing through the interaction between two types of information. In general, the enhanced feature extraction network comprises a residual‐like convolution module, which can reduce the loss of detailed information (e.g., edge contours) and further extract high‐level semantic information from the deep network. Besides, it performs feature fusion in multiple regions in the enhanced feature extraction network, such that the multi‐scale adaptability of the neural network is effectively enhanced. Last, the fused feature information at different scales is decoded, and the final detection results are yielded.
Mesenteric Adipose Tissue‐Derived Klebsiella variicola Disrupts Intestinal Barrier and Promotes Colitis by Type VI Secretion System
Authors: Gong Junli , Yu Jing , Yin Shengmei , Ke Jia , Wu Jinjie , Liu Chen , Luo Zhanhao , Cheng Wai Ming , Xie Yaozu , Chen Yuan , He Zhen , Lan Ping 
Published: February 2023

AbstractMesenteric adipose tissue (MAT) in Crohn's disease (CD) is associated with transmural inflammation. Extended mesenteric excision can reduce surgical recurrence and improve long‐term outcomes, indicating that MAT plays an important role in the pathogenesis of CD. Bacterial translocation has been reported to occur in the MAT of patients with CD (CD‐MAT), but the mechanisms by which translocated bacteria lead to intestinal colitis remain unclear. Here it is shown that members of Enterobacteriaceae are highly enriched in CD‐MAT compared with non‐CD controls. Viable Klebsiella variicola in Enterobacteriaceae is isolated exclusively in CD‐MAT and can induce a pro‐inflammatory response in vitro and exacerbates colitis both in dextran sulfate sodium (DSS)‐induced colitis mice model and IL‐10−/− spontaneous colitis mice model. Mechanistically, active type VI secretion system (T6SS) is identified in the genome of K. variicola, which can impair the intestinal barrier by inhibiting the zonula occludens (ZO‐1) expression. Dysfunction of T6SS by CRISPR interference system alleviates the inhibitory effect of K. variicola on ZO‐1 expression and attenuated colitis in mice. Overall, these findings demonstrate that a novel colitis‐promoting bacteria exist in the mesenteric adipose tissue of CD, opening a new therapeutic avenue for colitis management.
Lipid Nanoparticles Deliver the Therapeutic VEGFA mRNA In Vitro and In Vivo and Transform Extracellular Vesicles for Their Functional Extensions
Authors: Nawaz Muhammad , Heydarkhan‐Hagvall Sepideh , Tangruksa Benyapa , González‐King Garibotti Hernán , Jing Yujia , Maugeri Marco , Kohl Franziska , Hultin Leif , Reyahi Azadeh , Camponeschi Alessandro , Kull Bengt , Christoffersson Jonas , Grimsholm Ola , Jennbacken Karin , Sundqvist Martina , Wiseman John , Bidar Abdel Wahad , Lindfors Lennart , Synnergren Jane , Valadi Hadi 
Published: February 2023

AbstractLipid nanoparticles (LNPs) are currently used to transport functional mRNAs, such as COVID‐19 mRNA vaccines. The delivery of angiogenic molecules, such as therapeutic VEGF‐A mRNA, to ischemic tissues for producing new blood vessels is an emerging strategy for the treatment of cardiovascular diseases. Here, the authors deliver VEGF‐A mRNA via LNPs and study stoichiometric quantification of their uptake kinetics and how the transport of exogenous LNP‐mRNAs between cells is functionally extended by cells’ own vehicles called extracellular vesicles (EVs). The results show that cellular uptake of LNPs and their mRNA molecules occurs quickly, and that the translation of exogenously delivered mRNA begins immediately. Following the VEGF‐A mRNA delivery to cells via LNPs, a fraction of internalized VEGF‐A mRNA is secreted via EVs. The overexpressed VEGF‐A mRNA is detected in EVs secreted from three different cell types. Additionally, RNA‐Seq analysis reveals that as cells’ response to LNP‐VEGF‐A mRNA treatment, several overexpressed proangiogenic transcripts are packaged into EVs. EVs are further deployed to deliver VEGF‐A mRNA in vitro and in vivo. Upon equal amount of VEGF‐A mRNA delivery via three EV types or LNPs in vitro, EVs from cardiac progenitor cells are the most efficient in promoting angiogenesis per amount of VEGF‐A protein produced. Intravenous administration of luciferase mRNA shows that EVs could distribute translatable mRNA to different organs with the highest amounts of luciferase detected in the liver. Direct injections of VEGF‐A mRNA (via EVs or LNPs) into mice heart result in locally produced VEGF‐A protein without spillover to liver and circulation. In addition, EVs from cardiac progenitor cells cause minimal production of inflammatory cytokines in cardiac tissue compared with all other treatment types. Collectively, the data demonstrate that LNPs transform EVs as functional extensions to distribute therapeutic mRNA between cells, where EVs deliver this mRNA differently than LNPs.