bluuebunny/crossref_metadata_2025_split huggingface dataset:
Subseasonal prediction framework for tropical cyclone activity in the Solomon Islands region
Authors: Haruhiru Alick , Chand Savin S. , Sultanova Nargiz , Ramsay Hamish , Sharma Krishneel K. , Tahani Lloyd 
Published: July 2023

AbstractRecently, we developed seasonal prediction schemes with improved skill to predict tropical cyclone (TC) activity up to 3 months in advance for the Solomon Islands (SI) region (5°–15°S, 155°–170°E) using sophisticated Bayesian regression techniques. However, TC prediction at subseasonal timescale (i.e., 1–4 weeks in advance) is not being researched for that region despite growing demands from decision makers at sectoral level. In this paper, we first assess the feasibility of developing subseasonal prediction frameworks for the SI region using a pool of predictors that are known to affect TC activity in the region. We then evaluate multiple predictor combinations to develop the most appropriate models using a statistical approach to forecast weekly TC activity up to 4 weeks in advance. Predictors used include indices of various natural climate variability modes, namely the Madden–Julian Oscillation (MJO), the El Niño–Southern Oscillation (ENSO), the Indian Ocean Dipole (IOD) and the Interdecadal Pacific Oscillation (IPO). These modes often have robust physical and statistical relationships with TC occurrences in the SI region and the broader southwest Pacific territory as shown by preceding studies. Additionally, we incorporate TC seasonality as a potential predictor given the persistence of TCs occurring more in certain months than others. Note that a model with seasonality predictor alone (hereafter called the “climatology” model) forms a baseline for comparisons. The hindcast verifications of the forecasts using leave‐one‐out cross‐validation procedure over the study period 1975–2019 indicate considerable improvements in prediction skill of our logistic regression models over climatology, even up to 4 weeks in advance. This study sets the foundation for introducing subseasonal prediction services, which is a national priority for improved decision making in sectors like agriculture and food security, water, health and disaster risk mitigation in the Solomon Islands.
Quantitative proteomic analysis of tomato fruit ripening behavior in response to exogenous abscisic acid
Authors: Wu Qiong , He Yanan , Cui Chunxiao , Tao Xiaoya , Zhang Dongdong , Zhang Yurong , Ying Tiejin , Li Li 
Published: July 2023

AbstractBACKGROUNDTo determine how abscisic acid (ABA) affects tomato fruit ripening at the protein level, mature green cherry tomato fruit were treated with ABA, nordihydroguaiaretic acid (NDGA) or sterile water (control, CK). The proteomes of treated fruit were analyzed and quantified using tandem mass tags (TMTs) at 7 days after treatment, and the gene transcription abundances of differently expressed proteins (DEPs) were validated with quantitative real‐time polymerase chain reaction.RESULTSPostharvest tomato fruit underwent faster color transformation and ripening than the CK when treated with ABA. In total, 6310 proteins were identified among the CK and treatment groups, of which 5359 were quantified. Using a change threshold of 1.2 or 0.83 times, 1081 DEPs were identified. Among them, 127 were upregulated and 127 were downregulated in the ABA versus CK comparison group. According to KEGG and protein–protein interaction network analyses, the ABA‐regulated DEPs were primarily concentrated in the photosynthesis system and sugar metabolism pathways, and 102 DEPs associated with phytohormones biosynthesis and signal transduction, pigment synthesis and metabolism, cell wall metabolism, photosynthesis, redox reactions, allergens and defense responses were identified in the ABA versus CK and NDGA versus CK comparison groups.CONCLUSIONABA affects tomato fruit ripening at the protein level to some extent. The results of this study provided comprehensive insights and data for further research on the regulatory mechanism of ABA in tomato fruit ripening. © 2023 Society of Chemical Industry.
Utilization of gallic acid‐crosslinked soy proteins as wall material for chia oil microencapsulation
Authors: Gimenez Paola A. , Bergesse Antonela E. , Mas Agustín Lucini , Martínez Marcela L. , González Agustín 
Published: July 2023

AbstractBackgroundChia oil represents the vegetable source with the highest content of omega‐3 fatty acids. However, the incorporation of polyunsaturated fatty acids into food is limited due to their susceptibility toward oxidation. This investigation aimed to study the microencapsulation of chia oil (CO), using gallic acid (GA) crosslinked‐soy protein isolate (SPI) as a wall material and its effect on its oxidative stability.ResultsMicrocapsules presented a moisture content, water activity, and encapsulation efficiency of around 2.95–4.51% (wet basis); 0.17 and 59.76–71.65%, respectively. Rancimat tests showed that with higher GA content, the induction period increased up to 27.9 h. The storage test demonstrated that the microencapsulated oil with crosslinked wall material has lower values of hydroperoxides and higher induction times concerning the non‐crosslinked oil. Finally, the fatty acid profile at this storage time indicated that microcapsules with GA did not have significant changes. In vitro digestion exhibited a reduction in the percentage of bioavailable oil for crosslinked microcapsules, but with no variations in its chemical quality, and an increase in the total polyphenols amount and antioxidant activity.ConclusionThe results obtained demonstrated that the microencapsulation of CO using SPI crosslinked with GA as wall material exerted a very important protective effect since a synergistic effect could be described between the microencapsulation effect and the antioxidant power of GA. © 2023 Society of Chemical Industry.
Direct analysis in real time of high‐quality extra virgin olive oils for the rapid and automatic identification of origin trademark
Authors: Mangraviti Domenica , Cafarella Cinzia , Rigano Francesca , Dugo Paola , Mondello Luigi 
Published: July 2023

AbstractBackgroundFollowing our previous research on the differentiation of Italian extra virgin olive oils (EVOOs) by rapid evaporative ionization mass spectrometry coupled to a tandem high resolution mass analyser, the present study deals with the evaluation of another direct mass spectrometry (direct‐MS) approach for the rapid and automatic discrimination of EVOOs. In particular, direct analysis in real time (DART‐MS) was explored as an ambient MS (AMS) source for the building of a top‐quality Italian EVOOs database and fast identification of unknown samples. A single quadrupole detector (QDa) was coupled with DART, taking advantage of a cost‐saving, user‐friendly and less sophisticated instrumental setup. Particularly, quickstrip cards, located on a moving rail holder, were employed, allowing for the direct analysis of 12 EVOO spots in a total analysis time of 6 min. The aim was to develop a reliable statistical model by applying principal component and linear discriminant analyses to clusterize and classify EVOOs according to geographical origin and cultivar, as main factors determining their nutritional and sensory profiles.ResultsSatisfactory results were achieved in terms of identification reliability of unknown EVOOs, as well as false positive risk, thus confirming that the use of AMS combined with chemometrics is a powerful tool against fraudulent activities, without the need for mass accuracy data, which would increase the analysis cost.ConclusionA DART ionization source with a compact and reliable QDa MS analyser allowed for rapid fingerprinting analysis. Furthermore, MS spectra provided quali‐quantitative information successfully related to EVOO differentiation. © 2023 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Is It Possible to Diagnose Surgical Uterine Prolapse With Transperineal Ultrasound? Multicenter Validation of Diagnostic Software
Authors: García‐Mejido José Antonio , Martín‐Martinez Alicia , González‐Diaz Enrique , Núñez‐Matas María José , Fernández‐Palacín Ana , Carballo‐Rastrilla Sonia , Fernández‐Fernández Camino , García‐Jimenez Rocío , Sainz‐Bueno José Antonio 
Published: July 2023

ObjectivesTo validate an ultrasound software that uses transperineal ultrasound to diagnose uterine prolapse (UP).MethodsMulticenter, observational and prospective study with 155 patients that had indications for surgical intervention for dysfunctional pelvic floor pathology. Each patient underwent an examination with Pozzi tenaculum forceps was performed in the operating room with the patient anesthetized, followed by surgical correction of stages II–IV UP. Transperineal ultrasound was used to assess the difference in the pubis–uterine fundus measurement. With a multivariate logistic regression binary model (with the measurement ultrasound at rest, the Valsalva maneuver and age) using nonautomated methods to predict UP. With the purpose of evaluating the model, a table with coordinates of the receiver operating characteristic (ROC) curve, after which sensitivity and specificity were assessed.ResultsA total of 153 patients were included (73 with a diagnosis of surgical UP). It was obtained from the AUC (0.89) of the probabilities predicted by the model (95% confidence interval, 0.84–0.95; P < .0005). Based on the ROC curve for the model, obtaining a sensitivity of 91.8% and a specificity of 72.7%, values that were superior to those for the clinical exam for surgical UP (sensitivity: 80.8%; specificity: 71.3%).ConclusionsWe validated software that uses transperineal ultrasound of the pelvic floor and patient age to generate a more reliable diagnosis of surgical UP than that obtained from clinical examinations.
Simulated effects of roadkill and harvest on the viability of a recovering bobcat population
Authors: Dyck Marissa A. , Shoemaker Kevin T. , Dennison Catherine C. , Popescu Viorel D. 
Published: July 2023

AbstractBobcats (Lynx rufus) were extirpated from many midwestern states in the mid‐1800s owing to habitat loss and overharvesting. Recently, bobcats have recolonized Ohio, USA, and neighboring states and given their furbearer status elsewhere, there is interest in opening a harvest season; however, demographic factors and viability of this population are currently unknown. We developed a spatial population simulation model to assess the long‐term viability of the bobcat population in Ohio in the face of 2 human‐induced factors limiting population growth: potential harvest and road mortality. We combined habitat suitability and road mortality risk data with vital rates for bobcats from Ohio and other populations to simulate possible scenarios for Ohio's population. Our baseline scenario simulations showed no risk of extinction for Ohio's bobcat population in the next 40 years, but population trajectories were lower and exhibited greater uncertainty when we modeled the population with a lower maximum density of animals per cell. At low harvest intensity (αh = 0.05), the bobcat population also exhibits low risk of extinction. When harvest intensity increases (αh = 0.1, 0.15) or when adults (≥2 yr) are targeted by harvest, simulations show declining populations, greater uncertainty in projections, and possible risk of extirpation. Our models indicated that if harvest and road mortality are additive, then the bobcat population could withstand marginal increases in road mortality (αr = 0.1) at low harvest intensity (αh = 0.05). Future increases in road mortality with higher harvest intensity (αh = 0.1, 0.15) were unsustainable. Our results can be used by wildlife managers to assist with decisions on population‐level management. This simulation model can easily be adapted for other large mammals and can be modified to assess a variety of ecological and anthropogenic influences to wildlife populations.
Effects of vegetation and topography on snowshoe hare relative abundance at the southern range periphery
Authors: McNitt David C. , Latta Emily M. , McMahon Jordan D. , Rustand Matthew C. 
Published: July 2023

AbstractThe conservation of snowshoe hares (Lepus americanus) and their habitat is a major focus in the American West, largely because of their importance to the federally threatened Canada lynx (Lynx canadensis). Understanding the habitat relationships of snowshoe hare populations at the southern periphery of their distribution is particularly important because a warming climate is reducing the mesic forests and persistent snow cover they require. Using fecal pellet density as an index, we examined the factors influencing snowshoe hare relative abundance at 2 study areas in the Southern Rocky Mountains by comparing suites of candidate models containing fine‐scale vegetation and topographical covariates. The Birdseye Gulch study area is within an extensive area containing high elevations, mesic forests, and Canada lynx occurrence. The Three Peaks study area consists of an isolated zone of high elevation and mesic forests surrounded by inadequate habitat and is absent of Canada lynx. Mean hare pellet density in Birdseye Gulch was 2.48 pellets ± 0.46 (SE)/ (n = 49) versus 2.24 ± 0.48/m2 (n = 57) at Three Peaks. Models containing fine‐scale vegetation variables best explained pellet densities at Birdseye Gulch. Pellet densities at Three Peaks were best explained by topographical variables, with much unexplained variation within all models. The differing trends in these areas may be due to the absence of resident Canada lynx at Three Peaks and differences in topography between the areas. Our results indicate that snowshoe hare populations can persist in the type of isolated habitat that is increasingly common at the southern range periphery; however, the use of vegetation management to conserve habitat in these areas may be less effective because of weaker associations with vegetation structure.
The Role of Parotid Gland Invasion in Adenoid Cystic Carcinoma of the External Auditory Canal
Authors: Li Feitian , Wang Jing , Feng Yisi , Shi Xunbei , Hsueh Chi‐Yao , Wu Qianru , Kong Dedi , Li Wei , Zhang Yibo , Dai Chunfu 
Published: July 2023

ObjectiveThis study aimed to investigate the significance of parotid gland invasion in predicting distant metastasis of adenoid cystic carcinoma in the external auditory canal.Study DesignSingle‐institution retrospective cohort study.MethodsA retrospective review of patients with adenoid cystic carcinoma of the external auditory canal who underwent surgery was performed. Information on patient demographics, parotid gland invasion, tumor stage, perineural invasion, lymphovascular invasion, and follow‐up data were collected and analyzed.ResultsOne hundred twenty‐nine patients were identified for review. Parotid gland invasion was noted in 45 patients (34.9%). Parotid gland invasion was significantly associated with tumor stage, perineural invasion, distant metastasis, and postoperative adjuvant therapy. Distant metastasis was noted in 30 patients (23.3%). Multivariate Cox proportional hazards analysis identified parotid gland invasion as an independent risk factor for predicting distant metastasis. The 5‐year distant metastasis‐free survival rate was 83.6% for patients without parotid gland invasion and 61.8% for patients with parotid gland invasion (p = 0.010).ConclusionsThe parotid gland invasion rate is relatively high in adenoid cystic carcinoma of the external auditory canal and is significantly related to tumor stage. Parotid gland invasion is associated with worse distant metastasis‐free survival.Level of Evidence4 Laryngoscope, 134:419–425, 2024
Identification of circulating T‐cell immunoglobulin and mucin domain 4 as a potential biomarker for coronary heart disease
Authors: Wang Mengyao , Gong Ke , Zhu Xinran , Chen Shasha , Zhou Jie , Zhang Hui , Han Jihong , Ma Likun , Duan Yajun 
Published: July 2023

AbstractEfferocytosis, the process of engulfing and removing apoptotic cells, is attenuated in vulnerable plaques of advanced atherosclerosis. T‐cell immunoglobulin and mucin domain 4 (TIMD4) is a recognition receptor protein for efferocytosis that has been implicated in atherosclerosis mouse models. However, the role of serum‐soluble TIMD4 (sTIMD4) in coronary heart disease (CHD) remains unknown. In this study, we analyzed serum samples collected from two groups: Group 1 (36 healthy controls and 70 CHD patients) and Group 2 (44 chronic coronary syndrome [CCS]) and 81 acute coronary syndrome [ACS] patients). We found that sTIMD4 levels in patients with CHD were significantly higher than those in healthy controls and were also higher in ACS than in CCS patients. The area under the receiver operating characteristic curve was 0.787. Furthermore, our in vitro results showed that low‐density lipoprotein/lipopolysaccharide activated p38 mitogen‐activated protein kinase, which in turn enhanced a disintegrin and metalloproteinase 17, resulting in increased secretion of sTIMD4. This impairment of macrophage efferocytosis promoted inflammation. Thus, this study is not only the first identification of a potential novel biomarker of CHD, sTIMD4, but also demonstrated its pathogenesis mechanism, providing a new direction for the diagnosis and treatment of CHD.
Molecular characterization of phenylketonuria patients from the North Region of Brazil: State of Pará
Authors: Bonfim‐Freitas Pedro E. , Andrade Roseani S. , Ribeiro‐dos‐Santos Ândrea K. , Silva Luiz C. Santana‐da 
Published: July 2023

AbstractBackgroundPhenylketonuria (PKU) is an autosomal recessive disease resulting from a deficiency of the enzyme phenylalanine hydroxylase (PAH). Hyperphenylalaninemias (HPA) due to PAH deficiency are accompanied by a wide variety of clinical, biochemical, and molecular features. To identify and characterize pathogenic variants in the PAH gene and establish a correlation between genotype and biochemical phenotype in patients with PKU from state of Pará in the North Region of Brazil.MethodsAll 13 exons of the PAH gene from 32 patients (21 PKU and 11 non‐PKU HPA) were amplified by PCR and submitted to DNA sequencing (Sanger). Biochemical data were obtained from the patients' medical records.ResultsMolecular analysis identified 17 pathogenic variants and 3 nonpathogenic variants. The most frequent pathogenic variants were IVS10‐11G>A (7.9%), p. Arg261Gln (7.9%), p. Val388Met (6.3%) and p. Ile65Thr (4.7%). Was observed correlations and inconsistencies between genotype and biochemical phenotype.ConclusionIn PKU patients from state of Pará, North Region of Brazil, a heterogeneous mutation spectrum was revealed, in which the most frequent mutations are variants commonly observed in other Brazilian studies and in the region of the Iberian Peninsula.
A dual‐band filtering crossover with large frequency ratio for microwave and millimeter‐wave applications
Authors: Wei Huanjie , Zhu Fang 
Published: July 2023

AbstractModern wireless communication systems require components that can support microwave and millimeter‐wave bands simultaneously. However, it is difficult for the existing dual‐band crossover configurations to achieve a frequency ratio larger than 5. In this letter, a dual‐band filtering crossover with a frequency ratio larger than 10 is presented for the first time. To implement such a large frequency ratio, a microstrip filtering crossover operating at microwave band and a substrate integrated waveguide filtering crossover operating at millimeter‐wave band are combined through the aperture coupling mechanism. As the two elements almost have no influence on each other, a high degree of design freedom over two bands can be obtained. For demonstration, a dual‐band filtering crossover operating at 2.4 and 28 GHz was designed, fabricated, and measured. Measured results are in good agreement with simulated ones, which validates the proposed structure.
Clinical and neurophysiological recovery of ulnar nerve conduction block at the elbow
Authors: Podnar Simon , Omejec Gregor 
Published: July 2023

AbstractIntroduction/AimsAn important mechanism of peripheral nerve motor and sensory dysfunction is conduction block (CB). However, recovery from mechanically induced CB has been rarely studied in humans. The aim of this study was to describe clinical, electrodiagnostic (EDx), and ultrasonographic (US) characteristics of CB recovery in ulnar neuropathy at the elbow (UNE).MethodsWe recruited a group of consecutive patients presenting to our EDx laboratory with UNE and >50% motor CB. Patients' histories were obtained and neurologic, EDx, and US examinations were repeated every 1–3 mo for at least 12 mo.ResultsWe studied 10 patients (5 men), with a mean age of 63 y (range, 51–81 y). In all affected arms CB was localized to the retrocondylar groove. Following conservative management, myometrically measured index finger abduction improved from a median of 49% to 100% relative to the contralateral index finger, and ulnar nerve CB decreased from a median of 74% to 6%. Most of the improvement took place within 8 mo of symptom onset, and 6 mo after receiving treatment instructions. Mean motor nerve conduction velocity improved from 15 to 27 m/s in the most affected 2‐cm ulnar nerve segment.DiscussionThe resolution of CB after typical chronic compression may take longer than after acute compression. This should be considered by clinicians when estimating prognosis for discussions with patients.
Self‐efficacy in the context of nursing education and transition to practice as a registered practitioner: A systematic review
Authors: Abusubhiah Mousa , Walshe Nuala , Creedon Rena , Noonan Brendan , Hegarty Josephine 
Published: July 2023

AbstractAimThe aim of this systematic review is to identify, describe and synthesize evidence from experimental studies conducted to measure and conceptualize self‐efficacy within the context of nursing education and the transition of nursing students to practice as a registered practitioners.DesignSystematic review.MethodsPapers were screened by four independent reviewers, and data were extracted using a standardized data extraction tool. The Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) guidance and checklists were used to guide this review.ResultsThe review included 47 studies, using a quasi‐experimental pre‐test–post‐test design (n = 39) and randomized control trials (n = 8). Various teaching and learning interventions were used to enhance self‐efficacy; however, there is no definitive conclusion to be drawn regarding the most effective educational interventions. Various instruments were used in the studies to measure self‐efficacy. 10 of these were related to general self‐efficacy, while 37 instruments measured self‐efficacy in the context of specific skills.