bluuebunny/crossref_metadata_2025_split huggingface dataset:
Two-year outcome of half-time photodynamic therapy for chronic central serous chorioretinopathy with and without choroidal neovascularization
Authors: Kamimura Aya , Miki Akiko , Kishi Maya , Okuda Mina , Hayashida-Hirano Mayuka , Sakamoto Mari , Matsumiya Wataru , Imai Hisanori , Kusuhara Sentaro , Nakamura Makoto 
Published: May 2023

Purpose
To compare the two-year outcome of half-time photodynamic therapy (htPDT) in chronic central serous chorioretinopathy (cCSC) with and without choroidal neovascularization (CNV).

Methods
In this retrospective study, we included 88 eyes of 88 patients with cCSC who underwent htPDT and were followed up for more than 24 months. Patients were divided into two groups with (21 eyes) or without (67 eyes) CNV before htPDT treatment. The best-corrected visual acuity (BCVA), central retinal thickness (CRT), subfoveal choroidal thickness (SCT), and the presence of subretinal fluid (SRF) were evaluated at baseline and at 1, 3, 6, 12, and 24 months after PDT.

Results
A significant intergroup difference was noted in terms of age (P = 0.038). Significant improvements in the BCVA and SCT were found at all time points in eyes without CNV but only at 24 months in eyes with CNV. CRT was significantly reduced in both groups at all time points. No significant intergroup differences were noted in terms of BCVA, SCT and CRT at all time points. There were significant differences in the rate of recurrent and persistent SRF between groups (22.4% (without CNV) vs. 52.4% (with CNV), P = 0.013, and 26.9% (without CNV) vs. 57.1% (with CNV), P = 0.017, respectively). The presence of CNV was significantly associated with the recurrence and persistence of SRF after initial PDT (P = 0.007 and 0.028, respectively). Logistic regression analyses showed that the baseline BCVA, and not the presence of CNV, was significantly associated with BCVA at 24 months after initial PDT (P < 0.01).

Conclusions
A htPDT for cCSC was less effective in eyes with CNV than in those without CNV regarding the recurrence and persistence of SRF. Additional treatment might be required in eyes with CNV during 24-month follow-up periods.
Health inequalities for older people from minority ethnic groups receiving palliative care and end of life care: A scoping review protocol
Authors: Aker Narin , Frost Rachael , Walters Kate , West Emily , Davies Nathan 
Published: May 2023

Objective
The proposed scoping review aims to explore international literature on how older people from minority ethnic groups engage with and utilise palliative and end of life care, investigate the barriers and facilitators, and compare how this varies between ethnicities and health conditions.

Introduction
Minority ethnic groups make up substantial parts of the populations of many countries around the world. Research has found that there are disparities in access to palliative care and end of life care among minority ethnic groups. Language barriers, cultural values, and socio-demographic factors have been cited as preventing access to quality palliative and end of life care. However, it is unclear how these barriers and inequalities differ across different minority ethnic groups in different countries, and across different health conditions within these groups.

Inclusion criteria
The population will be older people of different minority ethnic groups who are receiving palliative or end of life care, family caregivers, and health and social care professionals. The sources of information will include quantitative, qualitative and mixed methods research, and sources that focus on minority ethnic groups’ interactions with palliative and end of life care.

Methods
A scoping review guided by the Joanna Briggs Institute Manual for Evidence Synthesis. Searches of MEDLINE, Embase, PsycInfo, CINAHL, Scopus, Web of Science, Assia, and the Cochrane Library will be conducted. Citation tracking, reference list checking and grey literature searches will be undertaken. Data will be extracted, charted and summarised descriptively.

Implications
This review will highlight the health inequalities present in palliative and end of life care, the research gaps in understudied minority ethnic populations, locations where further study is required, and how barriers and facilitators differ across different ethnic groups and health conditions. The results of this review will be shared with stakeholders and will provide evidence-based recommendations for inclusive palliative and end of life care.
Re-Focus: The Films of Shyam Benegal, Sneha Kar Chaudhuri and Ramit Samaddar (Eds) (2022)
Authors: Dutta Subham 
Published: May 2023

Review of: Re-Focus: The Films of Shyam Benegal, Sneha Kar Chaudhuri and Ramit Samaddar (Eds) (2022)
Edinburgh: Edinburgh University Press, 255 pp.,
ISBN 978-1-47445-286-1, h/bk, £90
Potential of B-Cell Epitopes Protein Ag85 Complex Mycobacterium Tuberculosis as Serodiagnostic Antigen of Tuberculosis by in Silico Study
Authors: Mufida Diana Chusna , Aziz Ayu Munawaroh , Misturiansyah Nurrul Izza 
Published: May 2023

Background: The high case of tuberculosis which isn't followed by good detection becomes an urgency for the diagnostic developments. One of them with immunodiagnostic principle uses B-cell Ag85 complex epitope. The design of the diagnostic epitope was performed by mapping the B cell epitope used in silico studies.Objective: The purpose of this research is to analyze antigenicity, physicochemical which affect immunogenicity, and homology of B-cell Ag85 complex epitope with the strain which circulates in Indonesia. Methods: The samples used were taken from the NCBI protein bank with access numbers P9WQP3 for Ag85A, P9WQP1 for Ag85B, and P9WQN9 for Ag85C. The sequences were analyzed using IEDB (Bepipred) software as the epitope prediction, VaxiJen as antigenicity prediction, ProtParam as physicochemical properties prediction, and BLASTP NCBI as sequence alignment.Results: Twenty seven epitopes were antigenic with 0.4297 to 2.6007 scores and the molecular weight was from 619.59 Da to 3145.36 Da. This research also obtained eleven stable and hydrophilic epitopes. The alignment of 11 candidate epitopes with the strain which circulates in Indonesia, had a similarity percentage of 85.71%-100% and 3 epitopes had a more significant score.Conclusion: Three epitopes of Ag85 complex; Ag85A (212-235), Ag85B (209-237), and Ag85C (283-310), were universal antigens and can be developed into diagnostic antigens in Indonesia.
Effect of Probiotic Supplementation on FSH, LH Levels and Folliculogenesis
Authors: Rahman Nur , Hidayat Syarief Thaufik , Adi Pramono Besari , Soerjo Hadijono Raden , Oerip Poerwoko Agoes , Anityo Mochtar Arufiadi 
Published: May 2023

Background: Polycystic ovary syndrome (PCOS) is an endocrine disorder that often occurs in women of reproductive age. The main therapy currently used to treat PCOS patients is insulin sensitizer. In PCOS, there is an imbalance in the intestinal flora which causes activation of the immune system and an inflammatory response that leads to insulin resistance. The effect of probiotic supplementation on insulin resistance can have an impact on changes in reproductive hormone levels in PCOS women. Objective: Analyze the effect of probiotic supplementation on levels of FSH, LH, and folliculogenesis in a study of PCOS Wistar rats. Methods: Experimental research with a post-test only controlled group design. The research sample was 35 Wistar rats which were divided into 5 groups, (K-) were healthy rats, (K+) were PCOS rats without treatment, (P1) were PCOS rats received Metformin, (P2) were PCOS rats received Probiotics, and (P3) were PCOS rats that received Metformin + Probiotics. The intervention was carried out for 14 days. The dependent variables were levels of FSH, LH and folliculogenesis. Research data were analyzed using one-way ANOVA test, Fisher Exact test. Differences between groups and controls were tested with Dunnett's post hoc test. Significant p<0.05Results: Metformin + probiotic supplementation resulted in increased FSH levels, decreased LH levels and increased folliculogenesis when compared to the PCOS rats without treatment (K+).Conclusion: Metformin + probiotic supplementation causes levels of FSH, LH and folliculogenesis activity in PCOS rats to resemble healthy rats.
A generalized fractional Pohozaev identity and applications
Authors: Djitte Sidy Moctar , Moustapha Mouhamed , Weth Tobias 
Published: May 2023

Abstract
We prove a fractional Pohozaev-type identity in a generalized framework and discuss its applications. Specifically, we shall consider applications to the nonexistence of solutions in the case of supercritical semilinear Dirichlet problems and regarding a Hadamard formula for the derivative of Dirichlet eigenvalues of the fractional Laplacian with respect to domain deformations. We also derive the simplicity of radial eigenvalues in the case of radial bounded domains and apply the Hadamard formula to this case.
A novel Beta matrix function via Wiman matrix function and their applications
Authors: Khan Nabiullah , Husain Saddam 
Published: May 2023

Abstract
Many authors defined and extended the beta function in various forms because the beta function has wide uses in different fields of science and applied science. In this article, we define a new more generalized form of the extended beta matrix function via the Wiman matrix function and describe their significant properties and special cases. Furthermore, we define an extension of the Gauss hypergeometric and confluent hypergeometric matrix functions by adopting a novel type of beta matrix function. We also derive their Laplace transform, derivative formula and transformation formulae.
A Cost-Efficient Space-Time Adaptive Algorithm for Coupled Flow and Transport
Authors: Bruchhäuser Marius Paul , Bause Markus 
Published: May 2023

Abstract
In this work, a cost-efficient space-time adaptive algorithm based on the Dual Weighted Residual (DWR) method is developed and studied for a coupled model problem of flow and convection-dominated transport.
Key ingredients are a multirate approach adapted to varying dynamics in time of the subproblems, weighted and non-weighted error indicators for the transport and flow problem, respectively, and the concept of space-time slabs based on tensor product spaces for the data structure.
In numerical examples, the performance of the underlying algorithm is studied for benchmark problems and applications of practical interest.
Moreover, the interaction of stabilization and goal-oriented adaptivity is investigated for strongly convection-dominated transport.
A comprehensive review on synergistic and individual effects of erosion–corrosion in ferrous piping materials
Authors: Sekar Annamalai , Bennet Anand Ronald 
Published: May 2023

Abstract
The degradation of materials due to erosion–corrosion occurs on the components that handle particle-laden corrosive slurry. The combined attack of mechanical erosion and corrosion shows increased material loss than the individual action of erosion and corrosion. The synergy accelerates material removal by eroding the corroded surface layer and corroding the surface due to the elimination of the passivating oxide layer by erosion. The synergism of erosion–corrosion is found to be more complex. Further, the coupled effect of mechanical erosion and electrochemical corrosion and the factors influencing erosion–corrosion still needs to be fully investigated. This review aims to provide a general and detailed summary of the interaction between erosion and corrosion of materials for the applications of pump impellers, pipelines for desalination, and oil and gas transportation. Importance is also given to the factors influencing erosion–corrosion, such as erodent particle properties (hardness, size, and shape), slurry properties (particle concentration, pH value, temperature), and flow characteristics (impingement angle, velocity). The various erosion models and the most used apparatus have also been reviewed.
Common best proximity points for a pair of mappings with certain dominating property
Authors: Charoensawan Phakdi , Dangskul Supreedee , Varnakovida Pariwate 
Published: May 2023

Abstract
This article introduces a type of dominating property, partially inherited from L. Chen’s, and proves an existence and uniqueness theorem concerning common best proximity points. A certain kind of boundary value problem involving the so-called Caputo derivative can be formulated so that our result applies.
Reliability Estimation of Parallel Repairable System under Uncertainty in Lifetime Data
Authors: K. Sruthi , Kumar Mahesh 
Published: May 2023

Abstract
Reliability is a popular concept that has been used in the manufacturing industry. In this paper, we consider a parallel system containing n non-identical and independent components in which each component is repairable except when all components are failed. As a special case, estimating the reliability of the system with identical components is considered. In real life, the data obtained for repair rate and failure rate could be subject to uncertainty. Here, to address this situation, failure and repair rates are considered as fuzzy numbers to estimate the reliability of the system. Fuzzy system reliability is estimated using fuzzy failure and repair rates, which are obtained by using confidence intervals and point estimators of failure rate and repair rate.
Joint distribution of the cokernels of random p-adic matrices
Authors: Lee Jungin 
Published: May 2023

Abstract
In this paper, we study the joint distribution of the cokernels of random p-adic matrices.
Let p be a prime and let

P
1

⁢

(
t
)

,
…
,

P
l

⁢

(
t
)

∈

ℤ
p

⁢

[
t
]

{P_{1}(t),\ldots,P_{l}(t)\in\mathbb{Z}_{p}[t]}

be monic polynomials whose reductions modulo p in

𝔽
p

⁢

[
t
]

{\mathbb{F}_{p}[t]}

are distinct and irreducible.
We determine the limit of the joint distribution of the cokernels

cok
⁡

(

P
1

⁢

(
A
)

)

,
…
,

cok
⁡

(

P
l

⁢

(
A
)

)

{{\operatorname{cok}}(P_{1}(A)),\ldots,{\operatorname{cok}}(P_{l}(A))}

for a random

n
×
n

{n\times n}

matrix A over

ℤ
p

{\mathbb{Z}_{p}}

with respect to the Haar measure as

n
→
∞

{n\rightarrow\infty}

.
By applying the linearization of a random matrix model, we also provide a conjecture which generalizes this result.
Finally, we provide a sufficient condition that the cokernels

cok
⁡

(
A
)

{{\operatorname{cok}}(A)}

and

cok
⁡

(

A
+

B
n

)

{{\operatorname{cok}}(A+B_{n})}

become independent as

n
→
∞

{n\rightarrow\infty}

, where

B
n

{B_{n}}

is a fixed

n
×
n

{n\times n}

matrix over

ℤ
p

{\mathbb{Z}_{p}}

for each n and A is a random

n
×
n

{n\times n}

matrix over

ℤ
p

{\mathbb{Z}_{p}}

.
Topological group actions by group automorphisms and Banach representations
Authors: Megrelishvili Michael 
Published: May 2023

Abstract
We study Banach representability for actions of topological groups on groups by automorphisms (in particular, an action of a group on itself by conjugations). Every such action is Banach representable on some Banach space. The natural question is to examine when we can find representations on low complexity Banach spaces.
In contrast to the standard left action of a locally compact second countable group G on itself, the conjugation action need not be reflexively representable even for

SL
2

⁡

(
ℝ
)

{\operatorname{SL}_{2}(\mathbb{R})}

.
The conjugation action of

SL
n

⁡

(
ℝ
)

{\operatorname{SL}_{n}(\mathbb{R})}

is not Asplund representable for every

n
≥
4

{n\geq 4}

.
The linear action of

GL
n

⁡

(
ℝ
)

{\operatorname{GL}_{n}(\mathbb{R})}

on

ℝ
n

{{\mathbb{R}}^{n}}

, for every

n
≥
2

{n\geq 2}

, is not representable on Asplund Banach spaces. On the other hand, this action is representable on a Rosenthal Banach space (not containing an isomorphic copy of

l
1

{l_{1}}

).
The conjugation action of a locally compact group need not be Rosenthal representable (even for Lie groups).
As a byproduct, we obtain some counterexamples about Banach representations of homogeneous G-actions

G
/
H

{G/H}

.
Antioxidant, antibacterial, and cytotoxicity potential of synthesized silver nanoparticles from the Cassia alata leaf aqueous extract
Authors: Sivasubramanian Kanagasabapathy , Sabarinathan Shanmugam , Muruganandham Moorthy , Velmurugan Palanivel , Arumugam Natarajan , Almansour Abdulrahman I. , Kumar Raju Suresh , Sivakumar Subpiramaniyam 
Published: May 2023

Abstract
The current research focuses on the silver nanoparticles (AgNPs) synthesis from the Cassia alata aqueous leaf extract. Various production parameters like pH (4, 5, 6, 7, 8, 9, and 10), metal ion concentration (1, 2, 3, 4, and 5 mM), and substrate (leaf extract) concentration (0.5, 1, 1.5, 2 and 2.5 mL) were optimized. UV-visible spectroscopy was used to identify the production by scanning the wavelength from 200 to 800 nm. Visual color change from light green to brown was designated as prior confirmation of the AgNP production. Physical characterization of AgNPs was carried out using scanning electron microscopy, Fourier-transform infrared spectroscopy, X-ray energy-dispersive spectroscopy, and X-ray diffraction. Furthermore, the obtained AgNPs show significant antibacterial activity for Staphylococcus aureus, Pseudomonas sp. Klebsiella sp., Proteus sp., and Enterobacter sp. The antioxidant potential was determined by α,α-diphenyl-β-picrylhydrazyl assay and cytotoxicity by (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) tetrazolium reduction assay on human lung cancer cell lines (A549). AgNPs confirmed potent antibacterial activity against skin infections, demonstrating their medicinal significance and are therefore crucial for creating a medicinal formulation with antibacterial properties.
Numerical analysis of a new mound-shaped extensional mixing element designed based on a sine curve in single-screw extrusion
Authors: He Hezhi , Li Weijie , Huang Zonghai , Tian Guidong , Zhu Zhiwen 
Published: May 2023

Abstract
The rapid development of polymer blends and nanocomposites has put forward new requirements for the mixing performance of extruders. In comparison with shear flow field, extensional flow field has been shown to have unique advantages in improving dispersive mixing performance and reducing energy consumption. However, building an extensional flow field in a conventional single-screw extruder remains challenging. In this work, a new mound-shaped extensional mixing element (M-EME) was designed based on the geometric characteristics of a sine curve. To investigate the effect of this M-EME on the mixing properties of a conventional single-screw extruder, a numerical simulation analysis of this M-EME was performed. The results showed that the proportion of the region with a mixing index greater than 0.55 in the M-EME was higher than 43 %, and that the highest mixing index of the M-EME reached around 0.9, confirming the dominance of the extensional flow field in the M-EME. Moreover, it was observed that the changes in amplitude and period of the sine function have no significant effect on the distribution of the mixing index. The findings from this work provide a viable way to generate extensional flow fields in conventional screw extruders.
Optimizing multi-level ReRAM memory for low latency and low energy consumption
Authors: Hosseinzadeh Shima , Klemm Marius , Fischer Georg , Fey Dietmar 
Published: May 2023

Abstract
With decreasing die size and the ability to store multiple bits in a single cell, resistive random access memory (ReRAM) can be used to increase storage density, making it a promising technology for the next generation of memory. However, multi-level write operations suffer from impairments such as large latency, high energy consumption, and reliability issues. In this paper, we study different mechanisms affecting the “multi-level incremental step pulse with verify algorithm” (M-ISPVA) on a 1-transistor-1-resistor (1T1R) model in transient simulation at the component and the circuit level with focus on resistance control and energy consumption during the entire process of state transitions. By dividing the M-ISPVA into a triggering and a controlling period, we discovered the transistor to operate in the ohmic region during the triggering period as a voltage-controlled resistance and in the saturation region during the controlling period as a voltage-controlled current limiter. Controlling the gate voltage in the triggering period can move the triggering point to a desired write voltage and in the controlling period can increase or decrease resistance steps per pulse to attain a desired speed of resistance change. In addition, the major energy portion is consumed for reset operation during triggering and for set operation during the controlling period. To optimize write performance, extra precaution must be taken when defining resistance states with target read-out current and gate voltage with the focus on evenly balanced latencies between all transitions. A direct multi-level write operation shows 67.5 % latency and 62.5 % energy saving compared to indirect ones, but suffers from only unidirectional control, making it non-feasible. In case of a 4 k bit memory, the more reliable M-ISPVA faces almost 37 % higher latency and energy compared to the basic ISPVA.
From Tractatus to Later Writings and Back – New Implications from Wittgenstein’sNachlass
Authors: de Queiroz Ruy J. G. B. 
Published: May 2023

AbstractAs a celebration of theTractatus100th anniversary it might be worth revisiting its relation to the later writings. From the former to the latter, David Pears recalls that “everyone is aware of the holistic character of Wittgenstein’s later philosophy, but it is not so well known that it was already beginning to establish itself in theTractatus” (The False Prison, 1987). From the latter to the former, Stephen Hilmy’s (The Later Wittgenstein, 1987) extensive study of theNachlasshas helped removing classical misconceptions such as Hintikka’s claim that “Wittgenstein in thePhilosophical Investigationsalmost completely gave up the calculus analogy.” Hilmy points out that even in theInvestigationsone finds the use of the calculus/game paradigm to the understanding of language, such as “in operating with the word” (Part I, §559) and “it plays a different part in the calculus”. Hilmy also quotes from a late (1946) unpublished manuscript (MS 130) “this sentence has use in the calculus of language”, which seems to be compatible with “asking whether and how a proposition can be verified is only a particular way of asking ‘How do you mean?’” Central in this back and forth there is an aspect which seems to deserve attention in the discussion of a semantics for the language of mathematics which might be based on (normalisation of) proofs and/or Hintikka/Lorenzen game-dialogue: the explication of consequences. Such a discussion is substantially supported by the use of the open and searchableThe Wittgenstein Archives at the University of Bergen. These findings are framed within the discussion of the meaning of logical constants in the context of natural deduction style rules of inference.