bluuebunny/crossref_metadata_2025_split huggingface dataset:
Studi Komparasi Pengelasan Tandem dan Multi-run terhadap Sifat Mekanis pada Sambungan Las Aluminium Paduan AA5083
Authors: Fatchunni'am Muhammad Afif , Ilman M. Noer 
Published: June 2023

ABSTRAK Aluminium paduan AA5083 banyak digunakan dalam industri konstruksi, otomotif dan perkapalan karena memiliki sifat-sifat fisik dan mekanis yang baik, yaitu bobot yang ringan, kekuatan tarik tinggi, sifat mampu las (weldability) yang baik dan tahan terhadap korosi. Salah satu metode penyambungan yang banyak digunakan di industri manufaktur untuk aluminium adalah teknik pengelasan metal inert gas (MIG) karena dapat menghasilkan sambungan las dengan kekuatan mekanik yang tinggi dibandingkan dengan teknik penyambungan lainnya. Pengelasan MIG memiliki keterbatasan apabila pelat yang akan disambung cukup tebal karena membutuhkan pengelasan beberapa kali (multi-run) sehingga memakan waktu yang relatif lama. Penggunaan metode pengelasan tandem dinilai dapat mempersingkat waktu produksi. Penelitian ini bertujuan untuk melakukan studi komparasi antara pengelasan multi-run dan tandem dengan jarak antar torch 50 mm dalam hal sifat-sifat mekanis las. Pengelasan dilakukan dengan menggunakan teknik las MIG dan elektroda ER5356. Hasil penelitian menunjukkan bahwa pengelasan tandem dapat mempercepat proses pengelasan namun memiliki kekuatan mekanis yang lebih rendah karena ukuran butiran las yang kasar dibandingkan pengelasan multi-run. Selain itu, distorsi yang terjadi pada pengelasan tandem lebih besar dibandingkan dengan pengelasan multi-run akibat masukan panas (heat input) pada las tandem yang tinggi. Kata kunci : AA5083, las tandem, multi-run, heat input, MIG. ABSTRACT Aluminum alloy AA5083 is widely used in the construction, automotive, and shipbuilding industries because it has good physical and mechanical properties, namely lightweight, high tensile strength, good weldability, and corrosion resistance. One of the joining methods widely used in the manufacturing industry for aluminum is the metal inert gas (MIG) welding technique because it can produce welded joints with high mechanical strength compared to other joining techniques. MIG welding has limitations if the plate to be joined is quite thick because it requires multiple welding (multi-run) so it takes a relatively long time. The use of the tandem welding method is considered to be able to shorten production time. This study aims to conduct a comparative study between multi-run and tandem welding with a torch distance of 50 mm in terms of the mechanical properties of the weld. Welding is done using MIG welding technique and ER5356 electrode. The results showed that tandem welding can increase the welding speed process but has lower mechanical strength due to the coarser grain size of the weld compared to multi-run welding. In addition, the distortion that occurs in tandem welding is greater than that of multi-run welding due to the high heat input of tandem welding. Keywords : AA5083, tandem welding, multi-run, heat input, MIG
Impact Factors on Subcontractor's Cash Flow Management
Authors: Youssef Medhat A. , Ibrahim Ahmed H. , El-Badawy Hafez M. El-Sayed 
Published: June 2023

Objective: This study aims to define how to maintain and protect the subcontractor firms' cash flow from economic fluctuation through legally sustainable solutions. Methods/Analysis: We conducted a case study in the Eastern Delta Region of Egypt. A questionnaire containing a list of 22 impact factors on subcontractors' cash flow was distributed across multiple subcontractor firms with an 82% response rate. It was designed to explore the factors causing cash flow instability and analyze them using SPSS statistics. Findings: The study finds that inflation, late payments, non-compensation for late payments, poor subcontractor cash flow management, subcontractor firms' inclination to avoid disputes, material price fluctuation, and non-compensation terms, as well as suppliers rejection of payment delays, are the most critical factors of subcontractor cash flow problems. Novelty/Improvement:The study suggests adding three sub-articles to Article 57 in "Tender Law" as legally sustainable solutions to protect and maintain the firm's growth rate from inflation, late payment, and the inclination to avoid disputes. Also, the study recommends that the owner ensure that cash is available before procuring the general contractors, as stated in Egyptian Law 182 of 2018. This study will contribute to establishing a sustainable win-win relationship between subcontractors and general contractors. Doi: 10.28991/CEJ-SP2023-09-08 Full Text: PDF
La huella ecológica dietética de los animales domésticos en Guayaquil, Ecuador
Authors: Sáenz De Viteri Anzules Cristian , Torres Lasso Pablo 
Published: June 2023

Como indicador de desarrollo sostenible, la huella ecológica ha logrado proporcionar una base para discutir los impactos ambientales del consumo humano. Los seres humanos son el origen de numerosas actividades contaminantes en la Tierra y son los principales impulsores del cambio climático. Sin embargo, se han realizado muy pocas investigaciones sobre los impactos ambientales de los animales, especialmente los animales domésticos, como perros y gatos, quienes necesitan cantidades significativas de comida para mantener sus necesidades energéticas diarias. Por lo tanto, la huella ecológica animal (HEA) dietética podría servir como un indicador útil para evaluar los impactos de las mascotas en el medio ambiente. En el presente artículo, explicamos el impacto ambiental de los perros y gatos de compañía cuantificando su HEA y las emisiones de gases de efecto invernadero (GEI) de acuerdo con los datos primarios recopilados en los tres Distritos de la ciudad Guayaquil en coordinación con la Facultad de Medicina Veterinaria y Zootecnia de la Universidad de Guayaquil y de la Unidad de Bienestar Animal de la Alcaldía de Guayaquil; los resultados muestran que la HEA dietética de perros y gatos de compañía con comida seca comercial en el distrito 3 o en el distrito 1 era aproximadamente dos veces mayor que el de los distrito 2. Se concluye que la mayoría de los perros y gatos de compañía en los Distritos 1, 2 y 3 de Guayaquil consumen más energía de la que realmente necesitan para mantener una actividad normal, lo que afecta en las emisiones de GEI y la HEA de la dieta.
DEPRESIÓN PERCIBIDA EN ADOLESCENTES Y ADICCIÓN AL INTERNET EN TIEMPOS DE PANDEMIA COVID-19
Authors: Mayorga-Benavides Yadira Jessenia , Larzabal-Fernández Aitor 
Published: June 2023

RESUMEN: El desarrollo de la pandemia COVID 19 ha interrumpido significativamente las actividades normales a nivel mundial. Durante este tiempo muchas personas en todo el mundo enfrentaron varios problemas de salud mental. En el presente estudio se analiza la relación entre la adicción al internet y la depresión en adolescentes durante el brote de COVID-19, en una muestra de 166 estudiantes de Bachillerato General Unificado de una unidad educativa en Quito-Ecuador. Se utiliza la escala Chen - Internet Addiction Scale, el 6-ITEM Kutcher Adolescent Depression Scale - KADS-6 y un Cuestionario Socio demográfico, incluye un diseño de tipo no experimental, enfoque cuantitativo, alcance correlacional y corte transversal. Los resultados en el análisis de correlación Pearson (r=.541), permitieron observar una relación positiva media y significativa entre la adicción al internet y la depresión. Se realizó un análisis de regresión lineal, con un valor de R2 de ,293 lo que indica que el 29 % de la varianza de la depresión adolescentes explicado por la adicción al internet. Debido al surgimiento del COVID-19 y al encierro ocasionado por el mismo, se ha observado que los adolescentes incrementen la cantidad de uso del internet, causando aislamiento y otros problemas mentales como depresión. Se sugiere posibles investigaciones a futuro en las cuales se indague más a fondo las secuelas psicológicas ocasionadas por la pandemia y la relación directa al abuso del internet.
Pengaruh Media Boneka Tangan Terhadap Kemampuan Mengendalikan Emosi Anak Kelompok B Di RA Al Almourky Kecamatan Telaga Kabupaten Gorontalo
Authors: Mbayang Wahyuningsih , Puspa Ardini Pupung , Sutisna Icam 
Published: June 2023

Kemampuan mengendalikan emosi adalah suatu kemampuan seseorang dalam menyadari dan mengontroll perasaannya baik positif maupun negatif untuk diarahkan kepada tindakan yang benar. Tujuan penelitian ini adalah untuk mengetahui apakah terdapat pengaruh media boneka tangan terhadap kemampuan mengendalikan emosi anak di Raudhatul Athfal Almourky. Penelitian ini merupakan penelitian eksperimen jenis One Group Pre-Test Post-Test Design. Populasi dalam penelitian ini berjumlah 124 anak. Sampel penelitian inii terdiri dari 20 anak kelas B2. Hasil penelitian menunjukan bahwa data Pre-Test memiliki rata-rata 15,4 dan standar deviasi 2,458. Sementara itu, data Post-Test memperoleh rata-rata 28,75 dan standar deviasi 3,462. Hal ini menunjukan bahwa skor rata-rata responden yang diuji dalam penelitian ini mengalami peningkatan dari tes awal hingga tes akhir. Dan diperoleh hasil thitung sebesar 2,411, dengan ttabel sebesar 2,093. Dapat diartikan bahwa media boneka tangan berpengaruh terhadap kemampuan mengendalikan emosi anak. Penelitian ini menegaskan bahwa media boneka tangan dapat diaplikasikan sebagai media pembelajaran yang dapat mengendalikan kemampuan emosi anak.
Menumbuhkan Budaya Literasi Bahasa Indonesia Melalui Metode Bernyanyi Gerak Dan Lagu Anak Usia 4-6 Tahun Di Sanggar Bimbingan Kepong Kuala Lumpur Malaysia
Authors: Safitri Linda , Pujiati Desti 
Published: June 2023

Penelitian ini membahas mengenai budaya literasi dan tujuan dari penelitian ini adalah untuk mengetahui keadaan pendidikan literasi di Sanggar Bimbingan Kepong Malaysia, serta pembiasaan dalam Menumbuhkan Budaya Literasi Bahasa Indonesia. Metode yang digunakan pada penelitian ini adalah kualitatif deskriptif. Subjek penelitian ini adalah anak usia 4-6 tahun, di Desa Kepong, Kuala Lumpur, Malaysia, berjumlah 10. Teknik pengumpulan data yang digunakan dalam penelitian ini adalah observasi, wawancara, dan data angket. Instrumen penilaian yang digunakan yaitu lembar observasi menumbuhkan budaya liteasi bahasa indonesia. Kondisi warga imigran yang tidak memiliki dokumen resmi membuat anak-anak imigran tidak bisa mendaftar sekolah formal di Malaysia. Untuk mengatasi hal tersebut, maka dari pihak Pimpinan Muhammadiyah Malaysia membuka sekolah Sanggar Bimbingan Kepong yang bertujuan supaya anak-anak imigran yang tidak memiliki dokumen bisa bersekolah disana. Peneliti tergerak hatinya untuk meneliti keadaan literasi di Sanggar Bimbingan Kepong, Kuala Lumpur, Malaysia.
The Effect of Learning Leadership Managerial at the State of Cikande Elementary School
Authors: Laela Siti , Hanafi Muhammad Syadeli , Sudadio Sudadio 
Published: June 2023

This study purpose is determined how to describe or provide an overview and relationship between learning leadership managerial at the state of Cikande Elementary School. The research method use a descriptive correlational research. It reveals whether there is a relationship between various variables based on the size of the correlation coefficient. The data obtained in the form of descriptive and numerical processing using statistical methods used and then interpreted. In this study, the population or research targets were all teachers at State Elementary Schools in Cikande District, Serang Regency. Based on data from the Department of Education and Culture of Serang Regency, there are 32 public elementary schools in the education sector, consisting of 306 teachers. The sample size calculation uses a table developed. From this calculation, 171 samples were obtained. The total population of 464 and the sampling technique used is proportional random sampling. This study uses SEM analysis tools using the Lisrel program. The methodologically of the research design is causal and simultaneous, has a relatively complicated relationship, so testing using this method is to be able to test what the objectives of this study are.The result show the managerial ability of the principal affects the quality of the school, learning leadership affects school quality and the feasibility of the facilities affects the quality of the school.
Reflective Language Teaching: Practical Applications for TESOL Teachers. Thomas S. C. Farrell (2018). Bloomsbury Publishing. 292 pages. ISBN: 9781350021365 and 978-1350021358
Authors: Yukselir Ceyhun 
Published: June 2023

Book review:
Reflective Language Teaching: Practical Applications for TESOL Teachers. Thomas S. C. Farrell (2018). Bloomsbury Publishing. 292 pages. ISBN: 9781350021365 and 978-1350021358
REALISASI KESANTUNAN BERBAHASA DALAM KEGIATAN PRESENTASI DALAM PROSES PEMBELAJARAN BAHASA INDONESIA KELAS XI MAS BAHRUL ULUUM AL-KAMAL TA. 2022/2023
Authors: Sirait Zulkarnain , Akmal Akmal 
Published: June 2023

Kesantunan berbahasa merupakan aspek yang sangat penting dalam membentuk kebahasaan dan karaktersiswa. Oleh sebab itu, perlu diperhatikan aspek kesantunandalamberbahasasiswa.Penelitianinibertujuanuntuk mendeskripsikan penyimpangan dan pematuhan prinsip kesantunan berbahasa yang terjadi dalam kegiatan presentasi kelas pada siswa kelasXI MAS Bahrul Uluum Al-Kamal dalam hal pemilihan katadan cara berdiskusi yang santun. Metode yang digunakan dalam penelitian ini adalah metode deskriptif. Teknik yang digunakan dalam mengumpulkan data menggunakan teknik rekam danteknik simak dan catat. Analisis data menggunakan model analisis interaktif. Penentuan penyimpangan dan pematuhan prinsip kesantunan berbahasa didasarkan pada indikator kesantunan berbahasa yang diturunkan dari teori Leech.Hasil penelitian pada siswa kelasXI MAS Bahrul Uluum Al-Kamal menunjukkanbahwa jumlah penyimpangan prinsip kesantunan berbahasa yang terjadi pada kegiatan presentasi kelaslebihbesar dibandingkan dengan pematuhannya. Hal itu dibuktikan dengan hasil penelitian yang menunjukkan bahwa pentimbangan pada prinsip kesantunan berbahasa dalam kegiatan presentasi kelassiswa kelas XI MAS Bahrul Uluum Al-Kamal sebanyak 13 tuturan,sedangkan pematuhannya sebanyak 12 tuturan. Data penyimpangan prinsip kesantunan berbahasa berupa penyimpangan satu maksim dan dua maksim sekaligus dalam satu tuturan.Data penyimpangan prinsip kesantunan berbahasa satu maksim terdiri dari maksim kebijaksanaan, penerimaan, kemurahan dan kesimpatian. Penyimpangan dua maksim terdiri atas penyimpangan maksim penerimaan dan kesimpatian, maksim penerimaan dan kerendahan hati, serta maksim kebijaksanaan dan kemurahan.Sementaraitu, data pematuhan prinsip kesantunan berupa pematuhan satu maksim dan dua maksim sekaligus dalam satu tuturan terdiridarimaksim kebijaksanaan, kemurahan, dan kecocokan. Pematuhan dua maksim terdiri atas maksim kebijaksanaan dan kecocokan, maksim kebijaksanaan dan kemurahan, maksim kebijaksanaan dan penerimaan, serta maksim penerimaan dan kecocokan
De novo expansion formation in the outer curvature of the internal carotid artery after flow diverter deployment for an infectious cavernous carotid aneurysm: illustrative case
Authors: Osuki Takuya , Ikeda Hiroyuki , Uezato Minami , Kinosada Masanori , Kurosaki Yoshitaka , Chin Masaki 
Published: June 2023

BACKGROUND
Infectious aneurysms very rarely occur in the cavernous carotid artery. Recently, treatment by flow diverter implantation with preservation of the parent artery has been the treatment of choice.

OBSERVATIONS
A 64-year-old woman presented with stenosis at the C5 segment of the left internal carotid artery (ICA), followed by ocular symptoms within 2 weeks, with a de novo aneurysm in the left cavernous carotid artery and wall irregularity with stenosis from the C2 to C5 segments of the left ICA. Antimicrobial therapy was given for 6 weeks, and a Pipeline Flex Shield was implanted. Angiography 6 months after treatment showed complete obliteration of the infectious aneurysm and improvement of the stenosis. However, de novo expansions were formed in the outer curvature of C3 and C4 segments of the ICA where the Pipeline device had been deployed.

LESSONS
Aneurysms that develop rapidly and show shape changes over time, accompanied by fever and inflammation, may be associated with an infection. Because of the fragility in the irregular wall of the parent vessel associated with infectious aneurysms, de novo expansion may form in the outer curvature of the parent vessel after flow diverter placement; thus, careful follow-up is necessary.
The effect of Fas/FasL pathway blocking on apoptosis and stemness within breast cancer tumor microenvironment (preclinical study)
Authors: Abou Shousha Seham , Baheeg Suzan , Ghoneim Hossam , Zoheir Malak , Hemida Mahmoud , Shahine Yasmine 
Published: June 2023

Evasion of the immune system is the tumor’s key strategy for its maintenance and progression. Thus, targeting the tumor microenvironment (TME) is considered one of the most promising approaches for fighting cancer, where immune cells within the TME play a vital role in immune surveillance and cancer elimination. FasL is one of the most important death ligands expressed by tumor-infiltrating lymphocytes (TILs) and plays a vital role in eliminating Fas-expressing cancer cells via Fas/FasL pathway-induced apoptosis. However, tumor cells can express elevated levels of FasL inducing apoptosis to TILs. Fas/FasL expression is linked to the maintenance of cancer stem cells (CSCs) within the TME, contributing to tumor aggressiveness, metastasis, recurrence, and chemoresistance. This study is considered the first study designed to block the overexpressed FasL on the tumor cells within TME mimicking tissue culture system using rFas molecules and supplementing the Fas enriched tissue culture system with blocked Fas - peripheral blood mononuclear cells PBMCs (using anti-Fas mAb) to protect them from tumor counterattack and augment their ability to induce tumor cell apoptosis and stemness inhibition. A significantly increased level of apoptosis and decreased expression of CD 44 (CSCs marker) was observed within the east tumor tissue culture system enriched with Fas molecules and anti-Fas treated PBMCs and the one enriched with Fas molecules only compared to the breast tumor tissues cultured alone (p < 0.001). Accordingly, we can consider the current study as a promising proposed immunotherapeutic strategy for breast cancer.
circ_0058063 promotes breast cancer progression by upregulating DLGAP5 via sponging miR-557
Authors: Zhu Kongjun , Yi Cen , Tong Chuanming 
Published: June 2023

OBJECTIVE: Accumulating evidence indicates that circular RNAs (circRNAs) contribute to breast cancer (BC) development and progression. However, the role of circ_0058063 in BC and its underlying molecular processes remain unclear. METHODS: The expression of circ_0058063, miR-557, and DLGAP5 in BC tissues and cells was determined using real time quantitative PCR or western blotting. The functions of circ_0058063 in BC cells were detected using CCK-8, Transwell, caspase-3 activity, and xenograft tumor assays. The specific binding of circ_0058063/miR-557 and DLGAP5/miR-557 was verified using RNA immunoprecipitation (RIP) and dual-luciferase reporter assays. RESULTS: circ_0058063 expression was upregulated in BC tissues and cells. circ_0058063 knockdown inhibited proliferation and migration but promoted apoptosis in MCF-7 and MDA-MB-231 cells in vitro. In vivo studies further validated that the knockdown of circ_0058063 repressed tumor growth. Mechanistically, circ_0058063 directly sponged miR-557 and negatively regulated its expression. Additionally, miR-557 inhibition reversed the tumor-suppressive effects of the circ_0058063 knockdown on the survival of MDA-MB-231 and MCF-7 cells. Moreover, miR-557 directly targeted DLGAP5. DLGAP5 knockdown suppressed MCF-7 and MDA-MB-231 cell growth, and these effects were reversed by miR-557 downregulation. CONCLUSION: Our findings verify that circ_0058063 acts as a sponge for miR-557 to upregulate DLGAP5 expression. These findings suggest that the circ_0058063/miR-557/DLGAP5 axis is an important regulator of oncogenic function and may be a promising therapeutic target for BC.
Cerebrospinal Fluid Diagnostics of Alzheimer’s Disease in Patients with Idiopathic Normal Pressure Hydrocephalus
Authors: Vanninen Aleksi , Lukkarinen Heikki , Kokkola Tarja , Koivisto Anne M. , Kokki Merja , Musialowicz Tadeusz , Hiltunen Mikko , Zetterberg Henrik , Leinonen Ville , Herukka Sanna-Kaisa , Rauramaa Tuomas 
Published: June 2023

Background: Alzheimer’s disease (AD) is the most common cause of dementia worldwide and a frequent comorbidity in idiopathic normal pressure hydrocephalus (iNPH). The presence of AD pathology is associated with worse outcomes after a shunt procedure in iNPH. Preoperative diagnosis of AD is challenging in patients with iNPH, which involves reduced concentrations of the cerebrospinal fluid (CSF) AD biomarkers. Objective: Our aim was to estimate the effect size of iNPH as a factor in CSF levels of AD biomarkers and to test if correction could be used to improve diagnostic value. Methods: Our cohort included 222 iNPH patients with data in the Kuopio NPH registry and brain biopsy and CSF samples available. We divided the patients into groups according to AD pathology per brain biopsy. For control cohorts, we had CSF samples from cognitively healthy individuals (n = 33) and patients with diagnosed AD and no iNPH (n = 39). *-31pt Results: Levels of all investigated biomarkers differed significantly between groups, with the exception of t-Tau levels between healthy individuals and iNPH patients with AD pathology. Applying a correction factor for each biomarker (0.842*Aβ1 - 42, 0.779*t-Tau, and 0.610*P-Tau181) for the effect of iNPH yielded a sensitivity of 2.4% and specificity of 100%. The ratio of P-Tau181 to Aβ1 - 42 was moderately effective in aiding recognition of AD pathology in iNPH patients (sensitivity 0.79, specificity 0.76, area under the curve 0.824). Conclusion: Correcting for iNPH as a factor failed to improve diagnostic effectiveness, but the P-Tau181/Aβ1 - 42 ratio showed some utility in the diagnosis of AD in iNPH patients.
What Patients Say: Large-Scale Analyses of Replies to the Parkinson’s Disease Patient Report of Problems (PD-PROP)
Authors: Marras Connie , Arbatti Lakshmi , Hosamath Abhishek , Amara Amy , Anderson Karen E. , Chahine Lana M. , Eberly Shirley , Kinel Dan , Mantri Sneha , Mathur Soania , Oakes David , Purks Jennifer L. , Standaert David G. , Tanner Caroline M. , Weintraub Daniel , Shoulson Ira 
Published: June 2023

Background: Free-text, verbatim replies in the words of people with Parkinson’s disease (PD) have the potential to provide unvarnished information about their feelings and experiences. Challenges of processing such data on a large scale are a barrier to analyzing verbatim data collection in large cohorts. Objective: To develop a method for curating responses from the Parkinson’s Disease Patient Report of Problems (PD-PROP), open-ended questions that asks people with PD to report their most bothersome problems and associated functional consequences. Methods: Human curation, natural language processing, and machine learning were used to develop an algorithm to convert verbatim responses to classified symptoms. Nine curators including clinicians, people with PD, and a non-clinician PD expert classified a sample of responses as reporting each symptom or not. Responses to the PD-PROP were collected within the Fox Insight cohort study. Results: Approximately 3,500 PD-PROP responses were curated by a human team. Subsequently, approximately 1,500 responses were used in the validation phase; median age of respondents was 67 years, 55% were men and median years since PD diagnosis was 3 years. 168,260 verbatim responses were classified by machine. Accuracy of machine classification was 95% on a held-out test set. 65 symptoms were grouped into 14 domains. The most frequently reported symptoms at first report were tremor (by 46% of respondents), gait and balance problems (>39%), and pain/discomfort (33%). Conclusion: A human-in-the-loop method of curation provides both accuracy and efficiency, permitting a clinically useful analysis of large datasets of verbatim reports about the problems that bother PD patients.