bluuebunny/crossref_metadata_2025_split huggingface dataset:
Distribution, pollution levels, and health risk assessment of heavy metals in groundwater in the main pepper production area of China
Authors: Eziz Mamattursun , Sidikjan Nazupar , Zhong Qing , Rixit Atiyagul , Li Xinguo 
Published: June 2023

Abstract
Heavy metal pollution of groundwater can have severe potential impacts on human health and the environment. The aim of this study was to evaluate the spatial distribution, pollution, and health risk of heavy metals in groundwater in the main pepper production area of China. A total of 67 groundwater samples were collected, and the concentrations of cadmium (Cd), chromium (Cr), copper (Cu), nickel (Ni), manganese (Mn), and zinc (Zn) elements were analyzed. The results indicated that the average concentrations of Cd, Cr, Cu, Mn, Ni, and Zn in groundwater are lower than the limits of the Standard for Groundwater Quality of China (Class III). However, the maximum concentrations of Mn, Cd, and Ni surpass the Standard for Groundwater Quality of China. The spatial distribution patterns of the concentrations and pollution levels of the six heavy metals in groundwater to be substantially heterogeneous. Furthermore, the pollution level of heavy metals in groundwater decrease in the following order: Mn > Cd > Ni > Cr > Zn > Cu, and the collected groundwater samples are found to be slightly polluted by heavy metals. Overall, the non-carcinogenic risk of the investigated metals, instigated primarily by oral ingestion of groundwater, are found to be higher than the acceptable range for children, and Cd poses the most significant health risk among the investigated metals.
Green synthesis of strontium-doped tin dioxide (SrSnO2) nanoparticles using the Mahonia bealei leaf extract and evaluation of their anticancer and antimicrobial activities
Authors: Aloufi Abeer S. 
Published: June 2023

Abstract
In this study, a simple green method was employed to produce strontium (Sr)-doped-tin-dioxide (SnO2) nanoparticles (SrSnO2 NPs) using the Mahonia bealei leaf extract. The synthesized NPs were characterized with XRD, FE-SEM, FTIR, and PL spectroscopy measurements. SrSnO2 NPs were analysed for antimicrobial and anticancer activities. The XRD analysis revealed that the synthesized samples exhibited a tetragonal rutile crystal structure type of tin oxide. The EDX spectrum conforms to the chemical composition and elemental mapping of SrSnO2 NP synthesis. At 632 cm−1, the O–Sn–O band was observed and chemical bonding was confirmed using an FTIR spectrum. The PL spectrum identified surface defects and oxygen vacancies. The SrSnO2 NPs were tested against both Gram-positive and Gram-negative human pathogens. The synthesized nanoparticles exhibited effective antibacterial properties. The anticancer effects of SrSnO2 nanoparticles were also assessed against MCF-7 cells, and growth was decreased with increasing concentrations of the nanoparticles. Dual staining revealed high apoptosis in SrSnO2 NP-treated MCF-7 cells, proving its apoptotic potential. To conclude, we synthesized and characterized potential SrSnO2 nanoparticles using a green approach from the Mahonia bealei leaf extract. Further, green SrSnO2 nanoparticles showed significant antibacterial and anticancer properties against breast cancer cells (MCF-7) through apoptosis, which suggests a healthcare application for these nanoparticles.
Association of health predictors with quality of life in children and adolescents
Authors: Visser Pâmela Mello , Enes Carla Cristina , Nucci Luciana B. 
Published: June 2023

Abstract

Objectives
To evaluate the association of health-related quality of life (HRQOL) with physical activity, food consumption, sleep duration and screen time in children and adolescents.

Methods
Cross-sectional study with 268 students aged 10–17 years from a public school in Brazil. The outcome variable was HRQOL score, evaluated by the Pediatric Quality of Life Inventory™ (PedsQL™). Exposure variables were habitual physical activity, food consumption, sleep duration, and screen time. A general linear model was used to estimate age-adjusted means and 95 % confidence interval (95 % CI) of HRQOL scores, and a multivariable analysis of variance to identify factors associated with lower/higher HRQOL scores. The study was approved by the Human Research Ethics Committee of the Pontifical Catholic University of Campinas.

Results
Overall HRQOL score was 70.3 (95 % CI: 68.0–72.6). Multivariable analyses showed lower HRQOL scores for those adolescents who: 1-were physically inactive (67.3; p=0.014); 2-sleep less than 6 h per night (66.8; p=0.003); 3-eat fruits and vegetables less than five days/week (68.9; p=0.027); and 4-eat fast food twice/week or more (68.6; p=0.036) when compared to their opposite groups. Screen time was not statistically significantly associated with total HRQOL.

Conclusions
The joint association found in our study suggests that at least three habits must change to improve the HRQOL of children and adolescents (physical activity, food consumption, and sleep duration). Therefore, interventions in schools to promote a healthy lifestyle to achieve a better HRQOL should include a multidisciplinary team to properly guide children and adolescents about these habits simultaneously.
Numerical investigations on sc-CO2 gas sequestration in layered heterogeneous deep saline aquifers
Authors: Pavan Tummuri Naga Venkata , Devarapu Srinivasa Reddy , Kudapa Vamsi Krishna , Govindarajan Suresh Kumar 
Published: June 2023

Abstract
Carbon capture and storage (CCS) technology is regarded as the feasible solution to mitigate CO2 emissions from the burning of fossil fuels in large-scale industries to meet energy demand. The storage of CCS requires the injection of CO2 gas captured from bulk sources into geological formations. Deep saline aquifers are the largest identified storage potential formations for injecting high volumes of gas. The safe storage of CO2 gas requires a better understanding of the gas migration and pore pressure buildup in the aquifer. In the present work, a numerical has been developed to study the various factors impacting the CO2 gas migration in the formation of both homogeneous and multi-layered deep saline aquifers. The numerical model has been history matched with an analytical solution and the plume thickness data reported by Nordbotten, J. M., M. A. Celia, and S. Bachu. (2005). “Injection and Storage of CO2 in Deep Saline Aquifers: Analytical Solution for CO2 Plume Evolution during Injection.” Transport in Porous Media 58 (3): 339–60. The saturation distribution and pressure buildup in the aquifer are different for each case. The relative permeability of gas increases in the homogeneous case. The drainage efficiency increases along with injection time in any formation. However, the drainage process is less in layered formation compared with homogeneous formation. The parameterized storage efficiency factor (Ɛ) is calculated to understand the storage capacity of the aquifer along the lateral direction near to injection well. The formations having low permeability in the top and below layers of the aquifer, the storage efficiency factor is high indicating more amount of gas is stored.
Harmony of Asymmetric Variants of the Filbert and Lilbert Matrices inq-form
Authors: Kiliç Emrah , Ersanli Didem 
Published: June 2023

ABSTRACTWe define a new matrix whose entries are defined by the idea of combining two different asymmetric rules. We will derive explicit formulæ for the matricesLandUcome fromLU-decomposition,L−1,U−1, inverse of the main matrix as well as its determinant. To prove the claimed results, we use backward induction method.
Dimension dependence of current injection path in GaInN/GaN multi-quantum-shell (MQS) nanowire-based light-emitting diode arrays
Authors: Katsuro Sae , Lu Weifang , Ito Kazuma , Nakayama Nanami , Inaba Soma , Shima Ayaka , Yamamura Shiori , Jinno Yukimi , Sone Naoki , Huang Kai , Iwaya Motoaki , Takeuchi Tetsuya , Kamiyama Satoshi 
Published: June 2023

Abstract
To light emitting diodes (LEDs), solving the common non-uniform current injection and efficiency degradation issues in (0001) plane micro-LED is essential. Herein, we investigated the light emission characteristics of various mesa sizes and different p-electrode areas toward the realization of coaxial GaInN/GaN multi-quantum-shell (MQS) nanowires (NWs)-based micro-LEDs. As the mesa area was reduced, the current leakage decreases, and further reduction of the area showed a possibility of realizing micro-LED with less current leakage. The large leakage path is mainly associated with the defective MQS structure on the (0001) plane area of each NW. Therefore, more NWs involved in an LED chip will induce higher reverse leakage. The current density-light output density characteristics showed considerably increased electroluminescence (EL) intensity as the mesa area decreased, owing to the promoted current injection into the efficient NW sidewalls under high current density. The samples with a mesa area of 50 × 50 µm2 showed 1.68 times higher light output density than an area of 100 × 100 µm2 under a current density of 1000 A/cm2. In particular, the emission from (1-101) and (10-10) planes did not exhibit an apparent peak shift caused by the quantum-confined Stark effect. Furthermore, by enlarging the p-electrode area, current can be uniformly injected into the entire chip with a trade-off of effective injection to the sidewall of each NW. High performance of the MQS NW-based micro-LED can be expected because of the mitigated efficiency degradation with a reducing mesa area and an optimal dimension of p-electrode.
Influence of Long-Lasting Static Stretching Intervention on Functional and Morphological Parameters in the Plantar Flexors: A Randomized Controlled Trial
Authors: Warneke Konstantin , Keiner Michael , Wohlann Tim , Lohmann Lars H. , Schmitt Tina , Hillebrecht Martin , Brinkmann Anna , Hein Andreas , Wirth Klaus , Schiemann Stephan 
Published: June 2023

Abstract
Warneke, K, Keiner, M, Wohlann, T, Lohmann, LH, Schmitt, T, Hillebrecht, M, Brinkmann, A, Hein, A, Wirth, K, and Schiemann, S. Influence of long-lasting static stretching intervention on functional and morphological parameters in the plantar flexors: a randomised controlled trial. J Strength Cond Res 37(10): 1993–2001, 2023—Animal studies show that long-lasting stretching training can lead to significant hypertrophy and increases in maximal strength. Accordingly, previous human studies found significant improvements in maximal voluntary contraction (MVC), flexibility, and muscle thickness (MTh) using constant angle long-lasting stretching. It was hypothesized that long-lasting stretching with high intensity will lead to sufficient mechanical tension to induce muscle hypertrophy and maximal strength gains. This study examined muscle cross-sectional area (MCSA) using magnetic resonance imaging (MRI). Therefore, 45 well-trained subjects (f: 17, m: 28, age: 27.7 ± 3.0 years, height: 180.8 ± 4.9 cm, mass: 80.4 ± 7.2 kg) were assigned to an intervention group (IG) that stretched the plantar flexors 6 × 10 minutes per day for 6 weeks or a control group (CG). Data analysis was performed using 2-way ANOVA. There was a significant Time × Group interaction in MVC (p < 0.001–0.019, ƞ2 = 0.158–0.223), flexibility (p < 0.001, ƞ2 = 0.338–0.446), MTh (p = 0.002–0.013, ƞ2 = 0.125–0.172), and MCSA (p = 0.003–0.014, ƞ2 = 0.143–0.197). Post hoc analysis showed significant increases in MVC (d = 0.64–0.76), flexibility (d = 0.85–1.12), MTh (d = 0.53–0.6), and MCSA (d = 0.16–0.3) in IG compared with CG, thus confirming previous results in well-trained subjects. Furthermore, this study improved the quality for the morphological examination by investigating both heads of the gastrocnemius with MRI and sonography. Because stretching can be used passively, an application in rehabilitation settings seems plausible, especially if no commonly used alternatives such as strength training are applicable.
Feasibility Study of an ASTM Standard in Determining the Mixed-Mode I-II Fracture Toughness of Asphalt Concrete Materials
Authors: Erarslan Nazife 
Published: June 2023

Abstract
The American Society for Testing and Materials (ASTM) has proposed ASTM D8044, Standard Test Method for Evaluation of Asphalt Mixture Cracking Resistance Using the Semi-circular Bend Test (SCB) at Intermediate Temperatures, to test the tensile fracture toughness (mode I) of asphalt concrete materials using semicircular disk bend specimens. However, one of the main objectives of this study is to investigate the feasibility of the ASTM D8044 standard for analyzing the mixed-mode I-II (tensile and shear) fracturing of asphalt concrete materials. This study is a comparative evaluation of experimental, analytical, and numerical analysis. The stress distribution and cohesive crack growth analysis were performed using the fracture mechanics program FRANC2D. Experimental results showed that the notched cracks opened at a 30° inclination angle (β) and kept opening up to β of 45°. The mode I fracture toughness (KIC) of asphalt concrete specimens was found to be 0.37 MPa√m. The KIC value, on the other hand, was determined to be 0.44 MPa√m for the 30° inclined crack and 0.40 MPa√m for the 45° inclined notch crack. The critical crack length was found to be 2–2.5 mm using critical crack threshold analysis. On the other hand, the critical crack length was found between 8 mm and 10 mm for the mixed-mode (I-II) loading. It is believed that this study could be considered an initial research on the use of semicircular disk bend geometry for asphalt concrete materials, not only for mode I test but also for mixed-mode loading tests and for the establishment of an international standard test.
Analysis of Hydrothermal Coupling Effect of Asphalt Pavement between Tunnels in Seasonally Frozen Area
Authors: Yang Enhui , Pang Chenxi , Luo Lei , Zhang Haopeng , Di Haibo , Yuan Feiyun , Qiu Yanjun 
Published: June 2023

Abstract
At present, research on the icing process of asphalt pavement between tunnels in seasonally frozen areas still relies on historical weather or laboratory simulation data to predict the occurrence of icing. However, these methods are time-consuming and the experimental data are discrete. In this article, according to the phase-change heat transfer, moisture migration, and stress-strain equations, the hydro-thermal-mechanical coupling models of asphalt pavement in seasonal frozen area under saturated water conditions were constructed through the secondary development of general finite element software. Additionally, an indoor icing experimental system was independently developed to verify the effectiveness of prediction model. The results show that the rutting plate temperatures of indoor experiment are close to the simulated results of prediction model. The influence level of ice-water phase transition on temperature field at the road surface becomes smaller as the water film freezes gradually, and the temperature change of road surface tends to be smooth after the water film is completely frozen. The moisture inside the SMA-13 subgrade surface section between the tunnels first freezes, then melts, and finally freezes again. The times when the ice content reaches maximum and minimum coincide with the times when the temperatures reach minimum and maximum. The stress variation amplitudes of the road surface and the top surface of the middle, lower, base, and sub-base layers are weakened in turn. The subgrade section between tunnels basically does not produce vertical displacements when the soil foundation is not subject to frost heave. Interestingly, the relatively obvious vertical displacements have occurred above soil foundation when the frost heave of soil foundation is considered, and the vertical displacement of the surface and base layers are relatively consistent. Therefore, the hydro-thermal-mechanical coupling models proposed in this article are effective for predicting the occurrence of icing for asphalt pavement.
Diş Çekiminden Sonra Gelişen Alveolit Vakalarının Değerlendirilmesi
Authors: AKKURT Oğulcan , TOPAL Olgun 
Published: June 2023

Amaç: Bu çalışmada, diş çekimi sonrası gelişen en sık komplikasyonlardan biri olan alveolar osteitis (alveolit) olgularının farklı parametreler kullanılarak değerlendirilmesi amaçlanmıştır.
Gereç ve Yöntemler: Çalışmaya 2019 ile 2022 tarihleri arasında Afyonkarahisar Sağlık Bilimleri Üniversitesi, Diş Hekimliği Fakültesi, Ağız, Diş ve Çene Cerrahisi Anabilim Dalına başvuran ve diş çekimi yapıldıktan sonra klinikte alveolit teşhisi konan 71 hasta dahil edilmiştir. Yaş, cinsiyet, diş çekimi yapılan bölge, sistemik hastalık varlığı, sigara kullanımı ve mevsim değişkenlerine göre alveolit görülmesi retrospektif olarak değerlendirilmiştir. Çalışmanın istatistiksel analizleri SPSS paket programı ile yapılmıştır.
Bulgular: Alveolit olgusu gelişen hastaların % 62’sinin kadın, % 38’inin erkek olduğu bulunmuş, cinsiyetler arasındaki dağılım anlamlı farklılık göstermiştir. Genç ve orta yaş gruplarında (21-60) alveolitin daha fazla görüldüğü bulunmuştur (p
[SPA] ESTAMPAS Y MODELOS: COPIA, PROCESO Y ORIGINALIDAD EN EL ARTE HISPANOAMERICANO Y ESPAÑOL DEL SIGLO XVIII // PRINTS AND MODELS: COPIES, PROCESS AND ORIGINALITY IN SPANISH AMERICAN AND SPANISH ART OF THE EIGHTEENTH CENTURY
Authors: Mues Orts Paula 
Published: June 2023

En la tradicional historiografía sobre arte novohispano, las influencias artísticassolían interpretarse como un proceso unidireccional, de Europa a la Nueva España,donde se recibían tardía y pasivamente. Este texto cuestiona esta visión y explorados casos principales de circulación de modelos artísticos: la influencia de tiposiconográficos y estilísticos italianos, en particular de Carlo Maratta, Carlo Dolce y IlSassoferrato; y en segundo, la de modelos franceses de Charles Le Brun, tanto delas estampas de las batallas de Alejandro Magno como de su teoría de lasexpresiones del alma. Se aborda la posibilidad de que estos modelos se compartieranen fechas muy próximas en los dos lados del océano, tomado como ejemplo la obrade pintores novohispanos de la capital virreinal, así como la del escultor murcianoFrancisco Salzillo.PALABRAS CLAVE: pintura novohispana, siglo XVIII, influencia italiana, influencia francesa, Francisco Salzillo, circulación de modelos ** The historiography of New Spanish art has traditionally analyzed influence asa one-directional process, from Europe to New Spain, and has worked on theassumption that models arrived late and were received passively. This articlequestions this view through the exploration of two major examples of circulation: in thefirst place, the influence of iconographic and stylistic typologies from Italy, especiallythrough the work of Carlo Maratta, Carlo Dolce, and Il Sassoferrato; and in the secondplace, the French models of Charles Le Brun, both through the series of prints of the Battles of Alexander the Great and his artistic theories of human expressions. The possibility that these sources were used early on both sides of the Atlantic is raised through an analysis of examples of the works of New Spanish painters from the viceregal capital and of the sculptor from Murcia, Francisco Salzillo.KEYWORDS: New Spanish painting, eighteenth century, Italian influence, Frenchinfluence, Francisco Salzillo, circulation
HPV16/18 Antibody Responses After a Single Dose of Nonavalent HPV Vaccine
Authors: Zeng Yi , Moscicki Anna-Barbara , Woo Heide , Hsu Chiu-Hsieh , Kemp Troy J. , Pinto Ligia A. , Szabo Eva , Dimond Eileen , Bauman Julie , Sahasrabuddhe Vikrant V. , Chow H-H Sherry 
Published: June 2023

OBJECTIVES
A single dose of human papillomavirus (HPV) vaccine would simplify logistics and reduce costs of vaccination programs worldwide. We conducted a phase IIa trial to determine the stability of HPV type-specific antibody responses after a single dose of the nonavalent HPV vaccine, Gardasil9.

METHODS
Two hundred-and-one healthy 9 to 11-year-old girls and boys were enrolled at 2 centers in the United States to receive a prime dose of the nonavalent vaccine at baseline, a delayed dose at month 24, and an optional third dose at month 30. Blood samples were collected to measure HPV type-specific antibodies at baseline and at 6, 12, 18, 24, and 30 months after the prime dose. The primary outcomes were serum HPV16 and HPV18 antibody responses.

RESULTS
In both girls and boys, geometric mean concentrations of HPV16 and HPV18 antibodies increased at 6 months, declined between months 6 to 12, and then remained stable and high (at 20- and 10-times those at baseline for HPV16 and HPV18, respectively) throughout months 12, 18, and 24 (prebooster) visits. Both HPV16 and HPV18 antibody responses demonstrated anamnestic boosting effect at 30-months after the delayed (24-month) booster dose.

CONCLUSIONS
A single dose of the nonavalent HPV vaccine induced persistent and stable HPV16 and HPV18 antibody responses up to 24 months. This study contributes important immunogenicity data to inform feasibility of the single dose HPV vaccination paradigm. Further research is needed to assess the long-term antibody stability and individual clinical and public health benefit of the single dose schedule.
The epidemiology of benzodiazepine-related toxicity in Ontario, Canada: a population-based descriptive study
Authors: Campbell Tonya J. , Men Siyu , Shearer Dana , Ebejer Terry , Joosse Matt , Quercia Josephine , Sanders Jane , Tadrous Mina , Antoniou Tony , Gomes Tara ,   on behalf of the Ontario Drug Policy Research Network Citizens’ Panel
Published: June 2023

Abstract
Objectives
Despite the widespread use of prescription benzodiazepines, there are few studies examining trends and patterns of benzodiazepine-related toxicity. We describe the epidemiology of benzodiazepine-related toxicity in Ontario, Canada.

Methods
We conducted a population-based, cross-sectional study of Ontario residents who had an emergency department visit or hospitalization for benzodiazepine-related toxicity between January 1, 2013 and December 31, 2020. We reported annual crude and age-standardized rates of benzodiazepine-related toxicity overall, by age, and by sex. In each year, we characterized the history of benzodiazepine and opioid prescribing among people who experienced benzodiazepine-related toxicity, and reported the percentage of encounters with opioid, alcohol, or stimulant co-involvement.

Results
Between 2013 and 2020, there were 32,674 benzodiazepine-related toxicity encounters among 25,979 Ontarians. During this period, the crude rate of benzodiazepine-related toxicity declined overall, from 28.0 to 26.1 per 100,000 population (age-standardized rate: 27.8 to 26.4 per 100,000), but increased among young adults aged 19 to 24 (39.9 to 66.6 per 100,000 population). Moreover, by 2020, the percentage of encounters associated with active benzodiazepine prescriptions had declined to 48.9%, while the percentage of encounters that had opioid, stimulant, or alcohol co-involvement rose to 28.8%.

Conclusion
Benzodiazepine-related toxicity has declined in Ontario overall, but has increased among youth and young adults. Furthermore, there is growing co-involvement of opioids, stimulants, and alcohol, which may reflect the recent emergence of benzodiazepines in the unregulated drug supply. Multifaceted public health initiatives comprising harm reduction, mental health supports, and promotion of appropriate prescribing are needed to reduce benzodiazepine-related harm.