bluuebunny/crossref_metadata_2025_split huggingface dataset:
Liebe Leserinnen und Leser der Klinischen Neurophysiologie,
Authors: Baum Petra , Metelmann Moritz 
Published: March 2023

wir begrüßen Sie sehr herzlich zum Schwerpunktheft
„Amyotrophe Lateralsklerose“.Bei der Amyotrophe Lateralsklerose (ALS) hat es in den letzten Jahren zahlreiche neue
Erkenntnisse gegeben. Die vereinfachten und für die klinische Praxis besser
geeigneten Gold Coast-Diagnosekriterien wurden eingeführt und die
Muskelsonographie hat Einzug in die Detektion von Faszikulationen gehalten. Daher
stellen wir in diesem Schwerpunktheft die Diagnostik der ALS in den Fokus.
Ophthalmologische Befunde durch Enzephalitozoon cuniculi
(Stamm III) bei einem Hund
Authors: Neuber Claudia , Koch Ulrike , Nell Barbara 
Published: March 2023

ZusammenfassungEine 2 Jahre alte Mischlingshündin wurde aufgrund chronischer Uveitis
vorgestellt. Die Hündin stammte aus Namibia. Es konnten sowohl ein
positiver Serum Antikörper-Titer als auch eine positive PCR aus dem
Kammerwasser auf Enzephalitozoon cuniculi nachgewiesen werden. Am linken
Auge zeigte sich eine immature anteriore fokale, kortikale Katarakt in der
Peripherie mit Verdacht einer Linsenkapselruptur und deutlichen Anzeichen einer
chronischen Uveitis. Am rechten Auge war eine inzipiente anteriore fokale,
kortikale Katarakt sichtbar. Trotz lokaler Therapie mit nicht-steroidalen
Antiphlogistika und Kortikoiden sowie einer systemischen Therapie mit Carprofen,
Prednisolon und Fenbendazol kam es zu wiederkehrenden Uveitiden. Das
Linsenmaterial wurde daraufhin durch Phakoemulsifikation entfernt. Die PCR des
Linsenmaterials war positiv auf Enzephalitozoon cuniculi Stamm III. Das
linke Auge ist durch eine erneute Uveitis mit sekundärem Glaukom 10
Monate nach der Phakoemulsifikation nicht mehr sehfähig. Beide Augen
sind zum Zeitpunkt der letzten Kontrolluntersuchung (31 Monate nach der
Phakoemulsifikation) reizlos und werden weiterhin entzündungshemmend
behandelt. Dieses ist der erste beschriebene Fall von einem durch
Enzephalitozoon cuniculi Stamm III hervorgerufenen Katarakt beim
Hund.
Vollstationäre Komplexbehandlung rheumatischer Krankheitsbilder
Authors: Adermann Jens , Holtschmit Jan Holger 
Published: March 2023

ZUSAMMENFASSUNGZur vollstationären Behandlung von Patienten mit rheumatologischen Erkrankungen, die eine hohe Krankheitsintensität haben, stehen verschiedene multimodale OPS-Codes zur Verfügung. Im Vordergrund steht der OPS 8-983 (multimodale rheumatologische Komplexbehandlung). Darüber hinaus werden in dem Artikel weitere Komplextherapiemöglichkeiten vorgestellt, die für Rheumapatienten geeignet sind.
Abschätzung der ambulanten Versorgungskapazitäten der internistischen Rheumatologie
Authors: Muth Theresia , Sollacher Anna , Froschauer Sonja , Bredow Laura 
Published: March 2023

ZUSAMMENFASSUNGDer vorliegende Artikel versucht anhand öffentlich zugänglicher Daten sowie Daten des Projekts „Versorgungsatlas Rheumatologie“ (VA) des Berufsverbandes Deutscher Rheumatologen e. V. die (ambulanten) Versorgungskapazitäten der internistischen Rheumatologie zu beschreiben. Unterschiedliche Definitionen und Datenquellen erschweren jedoch eine präzise Darstellung der Versorgungssituation. Dennoch kann gezeigt werden, dass die Anzahl der internistisch tätigen Rheumatologen jährlich weiter steigt – insbesondere im ambulanten Bereich. Die Ambulantisierung in der Rheumatologie wird auch durch das Angebot der ambulanten spezialfachärztlichen Versorgung (ASV) vorangetrieben. Allerdings zeigen die Daten des VA, dass über ⅓ der Rheumatologen in den nächsten 2 bis 5 Jahren in Rente gehen möchte. Zudem arbeiten 12 % der Befragten in Teilzeit. Das verdeutlicht, dass die Versorgungskapazitäten über die reine Anzahl an Rheumatologen nicht adäquat dargestellt werden kann. Insgesamt ist daher anzunehmen, dass der Mangel an internistisch tätigen Rheumatologen ohne zielgerichtete Gegenmaßnahmen weiterhin eine der wesentlichen Herausforderungen in der Versorgung bleiben wird.
Der Einsatz von Patient-reported Outcome Measures (PROM) und die
Perspektive digitaler Biomarker bei der Amyotrophen
Lateralsklerose
Authors: Maier André , Münch Christoph , Meyer Thomas 
Published: March 2023

ZusammenfassungDie systematische Erfassung des klinischen Zustands sowie der Erfahrung mit
Behandlung oder Versorgung durch einen strukturierten Bericht des Patienten wird
als „Patient-reported Outcome Measures“ (PROM) bezeichnet. Bei
der Amyotrophen Lateralsklerose (ALS) haben sich PROM insbesondere zur
Dokumentation funktioneller Defizite, z. B. mit der ALS-Funktionsskala,
und weiterer komplexer Symptome im Rahmen von klinischer Forschung etabliert. In
der Behandlungspraxis werden PROM dazu genutzt, den Verlauf und die Prognose der
Erkrankung einzuschätzen. Mit PROM werden neue biologische Biomarker
(z. B. Neurofilamente) und digitale Biomarker (z. B. durch den
Einsatz von Sensorik) auf ihre patientenzentrierte Relevanz evaluiert. Durch die
digitale Anwendung von PROM und die Verknüpfung mit digitalen Biomarkern
kann eine engmaschigere Erhebung von zu Hause aus erfolgen und damit die
Datenqualität erhöht werden. Patienten können selbst den
Gesundheitszustand monitorieren sowie Behandlungs- und Versorgungsergebnisse
dokumentieren. Damit nehmen sie zunehmend eine aktive Rolle in der individuellen
Behandlung und Versorgung ein.
Bedeutung der Muskelsonographie in der Detektion von Faszikulationen
bei der ALS
Authors: German Alexander , Türk Matthias , Schramm Axel , Regensburger Martin 
Published: March 2023

ZusammenfassungBei der amyotrophen Lateralsklerose sind Faszikulationen häufig bereits
in frühen Stadien in mehreren Körperregionen vorzufinden und
haben daher Eingang in die entsprechenden Leitlinien und Diagnosekriterien
gefunden. Während die invasive EMG-Diagnostik unverzichtbar zum Nachweis
von akut- und chronisch-neurogenen Veränderungen des elektrischen
Signalverhaltens motorischer Einheiten und zur Bestätigung von
Faszikulationspotenzialen bleibt, bietet die Muskelsonographie ein
hochsensitives Verfahren, um schnell und nicht-invasiv Faszikulationen in den
verschiedenen Muskel-Etagen zu erfassen. In dieser Übersichtsarbeit
stellen wir die bisherigen Daten zum Einsatz der Muskelsonographie zur
Faszikulationsdetektion dar. Durch ihren Einsatz ermöglicht die
Muskelsonographie im klinischen Alltag eine zielgerichtete und hierdurch
aussagekräftigere EMG-Diagnostik. Aktuelle Forschungsstudien zielen
darauf ab, Faszikulationen sonomorphologisch genauer zu charakterisieren, zu
quantifizieren und als Verlaufsparameter zu untersuchen.
Endoscopic Evacuation of Putaminal Hemorrhage Using the Trans-Middle Temporal Gyrus Approach: Technical Notes and Case Presentations
Authors: Yamazaki Ken , Ogiwara Toshihiro , Kitamura Satoshi , Fujii Yu , Yamazaki Daisuke , Kuwabara Haruki , Funato Kohei , Hanaoka Yoshiki , Horiuchi Tetsuyoshi 
Published: March 2023

Abstract
Background The development of minimally invasive endoscopic neurosurgery has enabled widespread application of endoscopic surgery via the ipsilateral transfrontal approach for putaminal hematoma evacuation. However, this approach is unsuitable for putaminal hematomas that extend into the temporal lobe. We adopted the endoscopic trans-middle temporal gyrus approach, instead of the conventional surgical approach, for the management of these complicated cases and determined its safety and feasibility.
Methods Twenty patients with putaminal hemorrhage underwent surgical treatment at the Shinshu University Hospital between January 2016 and May 2021. Of these, two patients with left putaminal hemorrhage that extended into the temporal lobe underwent surgical treatment using the endoscopic trans-middle temporal gyrus approach. The procedure entailed the use of a thinner transparent sheath to reduce the technique's invasiveness, a navigation system to determine the location of the middle temporal gyrus and the sheath's trajectory, and an endoscope with a 4K camera for higher image quality and utility. The sylvian fissure was compressed superiorly using our novel “port retraction technique” (i.e., by tilting the transparent sheath superiorly) to avoid damage to the middle cerebral artery and Wernicke's area.
Results The endoscopic trans-middle temporal gyrus approach allowed sufficient hematoma evacuation and hemostasis under endoscopic observation without any surgical complexities or complications. The postoperative course was uneventful in both patients.
Conclusion The endoscopic trans-middle temporal gyrus approach for putaminal hematoma evacuation helps avoid damage to normal brain tissue, which could result from the wide range of motion of the conventional technique, particularly when the hemorrhage extends to the temporal lobe.
Postherpetic Trigeminal Neuralgia of the V2 Branch Treated with Electrodes Placed through the Foramen Ovale: A Case Report
Authors: Cheng Sitong , Zhang Yue , Ou Cehua , Li Fubo 
Published: March 2023

AbstractVaricella-zoster virus (VZV) is a deoxyribonucleic acid (DNA) virus that causes both primary and recurrent viral infections. Herpes zoster (HZ), also known as shingles, is a unique condition that is induced by VZV reactivation. Neuropathic pain, malaise, and sleep disruption are prodromal symptoms in such cases. Postherpetic trigeminal neuralgia is a neuropathic pain caused by VZV infection of the trigeminal ganglion or branches, which remains or reappears after herpes crusting. In this report, we present a case of post-herpetic trigeminal neuralgia of the V2 branch, exhibiting findings of unusual involvement of the trigeminal nerve. Notably, the patient was treated using electrodes placed through the foramen ovale.
Feasibility and Results of a Mobile Haemophilia Outpatient Care Pilot Project
Authors: Schleicher Christian , Heine Sabine , Graf Norbert , von Mackensen Sylvia , Eichler Hermann 
Published: March 2023

Introduction Regular visits at haemophilia treatment centres (HTCs) in rural regions are often dependent on the access to a private car due to lack of or limited availability of public means. Therefore, a mobile haemophilia outpatient care (MHOC) concept providing home visits to haemophilia patients has been developed by the Saarland HTC, which is located in a rural German region.Methods Haemophilia patients and their parents were home visited at least twice (baseline, follow-up) by trained medical staff. Socio-demographic and clinical data were collected and interviews were performed asking the patients and parents about their needs and expectations towards such a MHOC.Results Seventy-nine patients were enrolled (56 adults, 23 children), 62.0% severely affected, 48.1% on prophylaxis, with a mean age of 37.4 ± 16.4 years (17–78) and 9.8 ± 4.2 years (3–16), respectively. Median travel distance to the HTC was 43.5 km (3–200). Note that 92.4% considered an intense binding to the HTC and a MHOC concept as ‘rather/very important’ (88.6%). They expected from a MHOC to provide consulting and educating activities, support in elderhood issues and treatment. For 35.4%, a MHOC could currently provide additional support, mainly due to patient's immobility and need of consultancy. They mainly used services in terms of consultancy in social–legal affairs and support in contacting authorities.Conclusion The results of this study support the hypothesis that a MHOC concept is a needful supplement in haemophilia comprehensive care and will improve the challenging haemophilia treatment, especially for those with limited access to HTCs or with disabilities.
Role of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy in the Management of Colorectal Peritoneal Metastases
Authors: Shah Rupen , Gangi Alexandra 
Published: March 2023

AbstractPeritoneal metastases from colon cancer are a particularly challenging disease process given the limited response to systemic chemotherapy. In patients with isolated peritoneal metastases, cytoreductive surgery with hyperthermic intraperitoneal chemotherapy offers a potential treatment option to these patients with limited peritoneal metastases as long as a complete cytoreduction is achieved. Decision about a patient's candidacy for this treatment modality should be undertaken by a multidisciplinary group at expert centers.
Low serum uric acid levels and levodopa-induced dyskinesia in Parkinson's disease
Authors: Soares Nayron Medeiros , Pereira Gabriela Magalhães , Dutra Ana Carolina Leonardi , Artigas Nathalie Ribeiro , Krimberg Júlia Schneider , Monticelli Bruno Elkfury , Schumacher-Schuh Artur Francisco , Almeida Rosa Maria Martins de , Rieder Carlos Roberto de Mello 
Published: March 2023

Abstract
Background Levodopa is the most used and effective medication for motor symptoms of Parkinson disease (PD), its long-term use is associated with the appearance of levodopa-induced dyskinesia (LID). Uric acid (UA) is believed to play an important neuroprotective role in PD.
Objective To investigate if serum UA levels are related with the presence of LIDs in PD patients. Also, we investigated the associations among UA levels and clinical features of PD.
Methods We enrolled 81 PD patients (dyskinesia = 48; no dyskinesia = 33) in the present study. A blood sample was collected to evaluate serum UA levels, clinical evaluation included the following instruments: Montreal Cognitive Assessment (MoCA), Beck Depression Inventory II (BDI-II), MDS-Unified Parkinson's Disease Rating Scale (MDS-UPDRS), Hoehn and Yahr (HY), and the sub-item 4.1 of MDS-UPDRS IV (score ≥ 1). Additional relevant clinical information was obtained by a clinical questionnaire.
Results Serum UA levels were lower in the dyskinesia group when compared with the no dyskinesia group. The same result was found in the UA levels of both men and women. The multivariate analysis showed lower uric acid levels were significantly associated with having dyskinesia (odds ratio [OR] = 0.424; 95% confidence interval [CI]: 0.221–0.746; p = 0.005). Additional analysis verified that serum UA levels are inversely correlated with depressive symptoms, disease duration, MDS-UPDRS IV and time spent with dyskinesia. A positive correlation was found with age at onset of PD symptoms.
Conclusions The present study provides a possible role of serum UA levels in LID present in PD patients.
Influence of the temperature on growth by ammonia source molecular beam epitaxy of wurtzite phase ScAlN alloy on GaN
Authors: Elias Caroline , Nemoz Maud , Rotella Hélène , Georgi Frédéric , Vézian Stéphane , Hugues Maxime , Cordier Yvon 
Published: March 2023

Due to its large piezoelectric and spontaneous polarization coefficients combined with the possibility of being grown lattice-matched with GaN, wide bandgap ScAlN is becoming a promising material in III-nitride semiconductor technology. In this work, and for the first time, ScAlN growth has been performed by molecular beam epitaxy with ammonia source as nitrogen precursor. High electron mobility transistor heterostructures with a 26 nm thick Sc0.15Al0.85N barrier have been grown on GaN-on-sapphire substrates. The effect of growth temperature, ranging between 620 and 800 °C, was carefully investigated. A smooth surface morphology with a mean roughness below 0.5 nm is obtained whatever the temperature while for 670 °C the (0002) and (101̄3) x-ray diffraction rocking curves show minimum full-width at half-maximum of 620 and 720 arc sec, respectively. Furthermore, two-dimensional electron gases with a high density of 3-3.5 × 1013/cm2 were evidenced in the heterostructures grown below 720 °C.
Idioms, proverbs and body part expressions onYiedie“wellbeing” in Akan
Authors: Agyekum Kofi 
Published: March 2023

AbstractThis paper investigates the interaction between language, culture, body and emotions. It is an aspect of cognitive semantics that discusses the Akan somatic nature of their body and therefore have existing lexical items, idioms and proverbs to comment on “wellbeing”. It is based on Conceptual Metaphor Theory byLakoff and Johnson (1980)and Ethnopragmatics byGoddard (2006). A great parts of Akan expressions for “wellbeing” are tapped from body parts through their physical, cognitive, and emotional representations. The nature of the derived semantic patterns and how the Akans consider these somatic expressions, idioms and proverbs as important aspects of their language and culture are discussed. This paper argues that “wellbeing” as an emotion is transitional like a pendulum; one can be enjoying aspects of “wellbeing” for a moment and be in “distress” and “depression” a moment later.1
Cognitive load and cognitive effort
Authors: Gieshoff Anne Catherine , Heeb Andrea Hunziker 
Published: March 2023

Abstract
The cognitive demands associated with performing a task involve at least two dimensions: (1) the load dimension
that is related to the assumed task difficulty and (2) the effort dimension that reflects the resources invested in a task. This
study considers whether this distinction is actually relevant to translators and interpreters when they report load and effort
and, if so, how the assumed psychological reality of these two dimensions is related to task performance. In this study,
professional translators and interpreters performed naturalistic tasks with comparable stimuli, working from English into German.
After each task, they were asked to rate their experienced load and effort as part of the NASA Task Load Index. Their performance
was measured by analysing process and product indicators that correspond in interpreting and translation. Results indicate that
while self-reported load and effort are highly correlated, their relationships to process or product measures appear to be more
complex.
Optimal Strategy of Primary Frequency Regulation for Wind-Storage System Considering Adaptive Parameter Control
Authors: Liu Yang , Yang Zhihao , Zhang Zhenan , Sun Xin , Wei Wenrong , Miao Shihong 
Published: March 2023

Abstract
For the problem that the power system has different demands on the frequency response characteristics in different segments of dynamic frequency response, this paper proposes an optimal primary frequency regulation strategy for the wind-storage system considering adaptive parameter control. Firstly, the dynamic frequency response processes of the system under single, continuous disturbances are analyzed to obtain the frequency regulation demand of the system in different segments. Secondly, the frequency response model of the power system is established to obtain the transfer function of the system’s primary frequency regulation. Finally, the adaptive parameter adjustment strategy of the wind-storage system is proposed, and the optimal primary regulation strategy of the wind-storage system is established. The result of the case study indicates that the proposed optimal primary frequency regulation strategy can effectively improve the performance of the power system in the dynamic frequency response process, especially when a continuous disturbance occurs.
Nano-TiO2/MWCNT composite coating with high DC flashover strength and super hydrophobicity
Authors: Liu Xi-Ying , Yao Hai-Bin , Jiang Tao , Zhu Chen , Song Da-Wei , Liu Zong-Jie , Xu Guo-Qiang , Wang Cheng-Quan , Li Bin , Song Wei-Ting , Qi Xiao-Wu 
Published: March 2023

Abstract
Epoxy resin (EP) materials are frequently used in high voltage power equipment because of their excellent electricity, force, and heat properties. However, under the condition of DC high voltage, the surface of EP insulation material is more likely to accumulate charge, which distorts the nearby electric field and causes flashover along the surface. In this article, a nanocomposite coating was prepared by spraying through the nanoparticles (TiO2 with carbon nanotubes) dispersed in the polydimethylsiloxane (PDMS) elastomers solution. Micro-nano porous structures are introduced in the spraying process, which hinders the development of collision ionization and increases the flashover strength of the coating. At the same time, the change in surface morphology makes the hydrophobic properties of the coating improve and enhances the anti-icing and anti-fouling capacity. Spraying nano filler provides a general method for improving hydrophobicity and flashover strength.
Research on High-angle operation Capability of Converter Valve Based on Thyristor Control Unit Optimization
Authors: Wan Quan , Yuan Hongtao , Huang Yongrui , Wei Zhuo , Xiang Guanteng , Wu Shuang , Tian Zhong , Yang Wen , Yang Nan , Shao Zhuke 
Published: March 2023

Abstract
When the converter valve operates at a high angle, the voltage stress borne by the internal electrical components increases, the loss of the damping circuit increases, and the junction temperature of the thyristor increases. For the influence of the harmonic component of valve voltage on thyristor energy extraction at a high angle, the thyristor control unit energy extraction circuit was optimized. Aiming at several typical high-angle operation conditions of ± 800kV hybrid cascade converter valve, the high-angle operation capability of the converter valve was studied and tested. Firstly, the electrical stress of the converter valve under different operating conditions of high angle was analyzed. Secondly, based on the engineering parameters of the Baihetan-Jiangsu UHVDC project, the operating parameters of the converter valve at high angles were calculated, and the most severe stress of the converter valve at high angles was extracted. Finally, based on the principle of the converter valve synthetic test circuit, the high-angle test parameters of the converter valve were calculated, and the high-angle operation test was carried out. The theoretical analysis and test results show that the electrical stress of the converter valve under high-angle working conditions is slightly higher than the rated operating condition, and the converter valve can withstand this stress, which can meet the requirements of long-term operation at a high angle.
Simulation Research of three phase bridge PWM Inverter based on MATLAB
Authors: Zhang Yusheng , Sun Lijiang 
Published: March 2023

Abstract
The sole method available to humans for precise control of power energy is power electronic technology, which is also a key trend in developing the future power system and the entire energy structure. PWM control technology regulates the pulse signal’s width, and this circuit can alter the fundamental amplitude and form of the input voltage. This study will evaluate the three-phase inverter circuit’s operating principle, develop its control strategy, create a SIMULINK simulation model, and do a rough analysis using an LC filter.
Research and Analysis of Equivalent Circuit Model for Core Snubber
Authors: Li Zhiheng , Ma Shaoxiang , Wang Yongmao , Zhu Bangyou , Zhang Hongqi , Zhang Ming , Pan Yuan , Yu Kexun 
Published: March 2023

Abstract
The ion source is the key to the NBI. It is very sensitive to overvoltage and overcurrent, and the breakdown frequently occurs between the acceleration grid. The core snubber is the most suitable surge suppression device to achieve DC fault protection. This paper introduces some basic concepts, comparing the core snubber’s material properties and important parameters. It also introduces the basic concept of an equivalent circuit model for snubber, including the derivation process and theoretical analysis. Then the characteristics of the snubber and surge suppression analysis are introduced. Finally, this paper looks forward to the future research direction of the snubber.