bluuebunny/crossref_metadata_2025_split huggingface dataset:
TiO2 nanotubes promote osteogenic differentiation of human bone marrow stem cells via epigenetic regulation of RMRP/DLEU2/EZH2 pathway
Authors: Li Shuangqin , Deng Qing , Si Qiqi , Li JinSheng , Zeng Huanghe , Chen Song , Guo Tailin 
Published: July 2023

Abstract
TiO2 nanotubes (TNTs) significantly promote osteogenic differentiation and bone regeneration of cells. Nevertheless, the biological processes by which they promote osteogenesis are currently poorly understood. Long non-coding RNAs (lncRNAs) are essential for controlling osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs). Epigenetic chromatin modification is one of the pathways in which lncRNAs regulate osteogenic differentiation. Here, we reported that TNTs could upregulate lncRNA RMRP, and inhibition of lncRNA RMRP in human BMSCs (hBMSCs) grown on TNTs could decrease runt-related transcription factor 2 (RUNX2), alkaline phosphatase, osteopontin, and osteocalcin (OCN) expression. Furthermore, we discovered that inhibiting lncRNA RMRP elevated the expression of lncRNA DLEU2, and lncRNA DLEU2 knockdown promoted osteogenic differentiation in hBMSCs. RNA immunoprecipitation experiments showed that lncRNA DLEU2 could interact with EZH2 to induce H3K27 methylation in the promoter regions of RUNX2 and OCN, suppressing gene expression epigenetically. According to these results, lncRNA RMRP is upregulated by TNTs to promote osteogenic differentiation through DLEU2/EZH2-mediated epigenetic modifications.
Wigner function dynamics with boundaries expressed as convolution
Authors: Seidov S S 
Published: July 2023

Abstract
In the present paper a method of finding the dynamics of the Wigner function of a particle in an infinite quantum well is developed. Starting with the problem of a reflection from an impenetrable wall, the obtained solution is then generalized to the case of a particle confined in an infinite well in arbitrary dimensions. It is known, that boundary value problems in the phase space formulation of the quantum mechanics are surprisingly tricky. The complications arise from nonlocality of the expression involved in calculation of the Wigner function. Several ways of treating such problems were proposed. They are rather complicated and even exotic, involving, for example, corrections to the kinetic energy proportional to the derivatives of the Dirac delta–function. The presented in the manuscript approach is simpler both from analytical point of view and regarding numerical calculation. The solution is brought to a form of convolution of the free particle solution with some function, defined by the shape of the well. This procedure requires calculation of an integral, which can be done by developed analytical and numerical methods.
Rotational vector-based analysis of turbulent structures in channel flow using large eddy simulation simulation
Authors: Zhang Shen , Gui Nan , Yang Xingtuan , Tu Jiyuan , Jiang Shengyao 
Published: July 2023

Abstract
Even with modern measurement techniques and data from direct numerical simulation (DNS), it is very difficult to identify the individual attached eddies and understand their dynamical behavior due to the multi-scale nature of the eddies in wall-bounded flows, which puts these issues at the center of the current debate. However, Liutex vector (
L
for short), a rotational vector field with information on both the rotation axis and swirling strength, has recently been developed by Prof. Liu’s group as a more accurate and clear definition of a vortex. Combining conventional and
L
methods may provide more detailed information about the complex flow structures as well as insights into the flow’s mixing and transport features. We simulated the channel flow in large eddy simulation by implementing an inflow condition based on the box turbulence. After validating the results with DNS data, we used
L
isosurfaces and their vector profiles to track ordered flow structures in wall-bounded turbulence. Based on the data, we observe numerous turbulent phenomena that have been described in other works with different visualization techniques. Moreover, the shear contamination on the wall is the most severe while all the root-mean-square
L
component variations are negligible. Due to the presence of background shear, the peak location of vorticity fluctuation is closer to the wall than the corresponding
L
fluctuation, and the displacement of peak location brought on by shear contamination is greatest for the spanwise component (z-component) of the vorticity fluctuation. According to the two-point correlation of
L
components, the streamwise size of turbulent structures does not vary considerably with

y
+

, however, the spanwise size of turbulent structures increases gradually as

y
+

increases.
Synthesis and characterization of wood-based phase change material with high photothermal conversion efficiency
Authors: Weng Lu , Lin Xianxian , Chen Xinyu , Liu Pengwei , Zhu Zezheng , Chen Yulian , Qiu Chendong , Lu Tonghua , Wei Renzhong , Zhang Yi , Sun Weisheng , Guo Xi 
Published: July 2023

Abstract
Phase change materials attract tremendous interest for building energy conservation due to their auto-temperature regulation and thermal energy storage capacity. However, its practical application is hindered due to the leakage problem and poor photothermal conversion efficiency. To address these issues, a scalable wood-based phase change material was prepared by impregnating polyethylene glycol (PEG) into wood particles doped with Fe3O4 and subsequent a hot press in this study. PEG was encapsulated by wood particles through its abundant pore structure and leakage rate of prepared wood-based phase change material (FWPCM) was only 2.9%, which solved the leakage problem effectively. FWPCM presented high latent heat of 73 J g−1 and slowed down the temperature change obviously. Addition of Fe3O4 powder endowed FWPCM a high photothermal conversion efficiency and thermal conductivity (0.3545 W/(m*K) was increased by 125% compared to PW. So FWPCM had potential to be used as building engineering material for energy collecting, storage and conversion benefited by its great thermal performance, superior durability, simple preparing process and acceptable mechanical property.
Gradient self-organized dislocation in expanded austenite layer during low-temperature nitriding
Authors: Che H L , Yang X , Liu H Y , Lei M K 
Published: July 2023

Abstract
A typical nitrogen expanded austenite layer is formed by plasma-based low-energy nitrogen ion implantation (PBLEII) on AISI 304L austenitic stainless steel at a moderate temperature of 380 °C. The dislocation self-organization structure in the nitrogen expanded austenite layer is characterized as an evolution from partial and Lomer-Cottrell dislocations in the inner layer near the interface to multilayer stacking faults in the outer nitrided layer. The self-organized dislocation density and forms are essentially dependent on the plastic deformation, strain-gradient, and nitrogen-related stacking fault energies, respectively, due to the constrained expansion in the nitrided layer. As the nitrogen concentration in the austenitic matrix increases, the stacking fault energy gradually decreases, resulting in the transformation of the defect from Lamer-Cottrell dislocations to multilayer stacking faults. The appropriate stress, which is associated with orderly stress relief during dislocation self-organization, preserves the integrity of the nitrided layer with a combinedly improved in wear and corrosion resistance. Nitriding-induced dislocation self-organization is basically explored as the formation mechanism of the nitrogen expanded austenite layer, contributing to the development of the specific low-temperature nitriding austenitic steel.
Efficient measurement schemes for bosonic systems
Authors: Gu Tianren , Yuan Xiao , Wu Bujiao 
Published: July 2023

Abstract
Boson is one of the most basic types of particles and preserves the commutation relation. An efficient way to measure a bosonic system is important not only for simulating complex physics phenomena of bosons (such as nuclei) on a qubit based quantum computer, but for extracting classical information from a quantum simulator/computer that itself is built with bosons (such as a continuous variable quantum computer). Extending the recently proposed measurement schemes for qubits, such as shadow tomography and other local measurement schemes, here we study efficient measurement approaches for bosonic systems. We consider truncated qudit and continuous variable systems, corresponding to simulated bosons on a discrete quantum computer and an inherent boson system, respectively, and propose different measurement schemes with theoretical analyses of the variances for these two cases. We numerically test the schemes for measuring nuclei vibrations simulated using a discrete quantum computer and a continuous variable Gaussian state, and the simulation results show great improvement of the performance of the proposed method compared to conventional ones.
Contrail radiative dependence on ice particle number concentration
Authors: De León Rubén Rodríguez , Lee David S 
Published: July 2023

Abstract
Recent studies on low aromatic fuels have shown that lower soot number emissions may reduce contrail ice particle number concentrations (N
ice). Here we implemented, in a sophisticated radiative transfer model, two ice particle size distribution schemes in order to estimate the contrail radiative forcing’s (RFs) dependence on these prospective N
ice reductions resulting from the introduction of sustainable aviation fuels. The results show that an 85% contrail N
ice reduction produces a 35% smaller contrail RF, while neglecting all non-radiative effects. This estimate of an RF reduction only considers the effects of the N
ice change assumed here, and neglects other potentially important microphysical mechanisms that may change the relationship between soot number emissions and N
ice. A comparison of our results with previous published estimates from full climate model simulations, shows similar RF reductions to those which also take into account non-radiative mechanisms, evidencing the need for more studies in order to allocate the contribution from radiative and non-radiative changes, as this would guide possible mitigation implementations. Despite these modeled contrail RF reductions being largely independent of the assumed ice water content (IWC), it is only through simultaneous improvement of the IWC and N
ice representation in models that contrail RF estimates can be better constrained. This is because our calculated RF varied by a factor of 3 when assuming a ±30% IWC range; and by a factor of 5 if a, still conservative, ±60% IWC range was prescribed, suggesting that the differences in the prescribed IWC and N
ice values in different models may explain the large discrepancies amongst published RF estimates. Recent estimates of higher N
ice values, and lower IWCs found in contrails even after several hours, compared to surrounding cirrus under similar atmospheric conditions, were assessed to conclude that it is mainly the differences in IWC that make young contrails have a smaller RF, and to reduce our previous estimate for linear contrail RF for year 2006 by 65%.
Barriers and Facilitators to Gender-affirming Hormone Therapy in the Veterans Health Administration
Authors: Wolfe Hill L , Boyer Taylor L , Shipherd Jillian C , Kauth Michael R , Jasuja Guneet K , Blosnich John R 
Published: July 2023

Abstract

Background
In 2011, the Veterans Health Administration (VHA) established a policy for the delivery of transition-related services, including gender-affirming hormone therapy (GAHT), for transgender and gender diverse (TGD) patients. In the decade since this policy’s implementation, limited research has investigated barriers and facilitators of VHA’s provision of this evidence-based therapy that can improve life satisfaction among TGD patients.

Purpose
This study provides a qualitative summary of barriers and facilitators to GAHT at the individual (e.g., knowledge, coping mechanisms), interpersonal (e.g., interactions with other individuals or groups), and structural (e.g., gender norms, policies) levels.

Methods
Transgender and gender diverse patients (n = 30) and VHA healthcare providers (n = 22) completed semi-structured, in-depth interviews in 2019 regarding barriers and facilitators to GAHT access and recommendations for overcoming perceived barriers. Two analysts used content analysis to code and analyze transcribed interview data and employed the Sexual and Gender Minority Health Disparities Research Framework to organize themes into multiple levels.

Results
Facilitators included having GAHT offered through primary care or TGD specialty clinics and knowledgeable providers, with patients adding supportive social networks and self-advocacy. Several barriers were identified, including a lack of providers trained or willing to prescribe GAHT, patient dissatisfaction with prescribing practices, and anticipated or enacted stigma. To overcome barriers, participants recommended increasing provider capacity, providing opportunities for continual education, and enhancing communication around VHA policy and training.

Conclusions
Multi-level system improvements within and outside the VHA are needed to ensure equitable and efficient access to GAHT.
Common Dyadic Coping Mediates the Associations Between We-Disease Appraisal and Relationship Satisfaction and Quality of Life in HIV Serodiscordant Couples: The Common Fate Mediation Model
Authors: Hou Jianhua , Fu Rong , Jiang Taiyi , Yu Nancy Xiaonan 
Published: July 2023

Abstract

Background
Since HIV has evolved into a lifelong but manageable condition, improving the quality of life (QoL) of persons living with HIV (PLWHs) has become increasingly important. Living with HIV is life-altering and poses substantial challenges for both PLWHs and their partners, so identifying how HIV serodiscordant couples cope with HIV together is crucial. Here, Bodenmann’s Systemic Transaction Model highlights common dyadic coping (CDC), which refers to both partners working together to alleviate the negative effects of stress.

Purpose
We examined the mediating role of CDC in linking we-disease appraisal with relationship satisfaction and QoL.

Methods
We recruited a convenience sample of 231 HIV serodiscordant couples via local grassroots organizations between June and October 2022. Participants completed measures of we-disease appraisal, CDC, relationship satisfaction, and QoL. We examined the mediation effect of CDC on the association between we-disease appraisal and outcomes using the common fate mediation model.

Results
The mean age of PLWHs was 32.18 years (standard deviation = 8.61 years), and that of their partners was 32.55 years (standard deviation = 9.24 years). The average time since HIV diagnosis was 4.18 years. Most couples were same-sex male couples. We found that CDC mediated the effect of we-disease appraisal on relationship satisfaction. Moreover, CDC significantly mediated the effect of we-disease appraisal on the QoL of PLWHs and their partners.

Conclusions
Our findings highlight the importance of CDC in dyadic illness management among Chinese HIV serodiscordant couples.
Acquisitive Prescription of Artwork and Other High-Value Movables: A Comparative Case Study of Litigation and Legislation in Louisiana, Germany, and Russia
Authors: Puder Markus G , Rudokvas Anton D 
Published: July 2023

Abstract
Using artwork and other valuables as a high-stakes case study, the Article discusses the law governing acquisitive prescription of movable property in Louisiana, Germany, and Russia. Rather than merely depicting what the law is from the perspective of a legal system’s respective silo, the Article develops a unique screen of test questions that have been intensely discussed by the courts and literature of the three sample jurisdictions when confronting prescription cases. What barriers, if any, does a jurisdiction erect with regard to the operations of prescription law? How are evidentiary burdens allocated with regard to good faith? Does the jurisdiction recognize tolling doctrines that do not reside in legislated law? What is the relationship between prescription and unjust enrichment? Controversies over art work and other high-value movables have inserted a powerful dose of drama into the discussion of these topics, which would have otherwise not received much attention in the public space. The Article concludes with the diagnosis that prescription law, one of property law’s core staples, is a fertile area of scholarly research with a particularly rich comparative yield. Louisiana, Germany and Russia differ widely as to the designs and operations of their prescription laws, which ultimately reflects distinct policies with regard to balancing the protection of ownership with the transformative effects of possession over time.
Immigrant Outreach and Language Access During First Year of the COVID-19 Pandemic
Authors: Dávila Liv T 
Published: July 2023

Abstract
This article applies cultural translation (Kramsch and Hua 2020) and geohistorical frameworks (Braudel 1949; Scott 2018) to analyze the interplay between linguistic, cultural, physical, and ideological proximities and distances in immigrant advocacy and outreach efforts. Data are taken from ‘small stories’ (Georgakopoulou 2010, 2015) shared by directors of immigrant-serving organizations in a small metropolitan area in the USA during the first year of the COVID-19 pandemic. These stories demonstrate directors’ situated perspectives on new and changing demands for communicating information in the face of persistent challenges associated with the digital divide, reaching clients with limited literacy and who speak indigenous languages of Central America and Africa, and cultivating trust among staff and between staff and clients around COVID-19 mitigation and relief. Findings trace how local, state, and national policies were taken up by individual participants and the communities they serve and bring to light the value of applied linguistics research in amplifying the complexities of language access in times of crisis as well as community resilience that are often hiding in plain sight.
Mastectomy Skin Flap Stability Prediction Using Indocyanine Green Angiography: A Randomized Prospective Trial
Authors: Kim Min Ji , Mok Jung Ho , Lee Il Jae , Lim Hyoseob 
Published: July 2023

Abstract

Background
The first step in successful breast reconstruction is obtaining a stable skin flap. Indocyanine green (ICG) angiography has recently been studied for its value and usefulness in predicting the stability of skin flaps; however, relevant prospective studies of its clinical efficacy are limited.

Objectives
The aim of this study was to prospectively investigate the clinical impact on breast reconstruction outcomes of the intraoperative use of ICG angiography.

Methods
Between March and December 2021, 64 patients who underwent immediate breast reconstruction at the authors’ institution were prospectively enrolled. They were classified into an experimental group (n = 39; undergoing ICG angiography) and a control group (n = 25; undergoing gross inspection alone). In the absence of viable skin, debridement was performed at the surgeon's discretion. Skin complications were categorized as skin necrosis (the transition of the skin flap to full-thickness necrosis) or skin erosion (a skin flap that did not deteriorate or become necrotic but lacked intactness).

Results
The 2 groups were matched in terms of basic demographic characteristics and incision line necrosis ratio (P = .354). However, intraoperative debridement was significantly more frequent in the experimental group (51.3% vs 48.0%, P = .006). The authors additionally classified skin flap necrosis into partial- and full-thickness necrosis, with a higher predominance of partial-thickness necrosis in the experimental vs control group (82.8% vs 55.6%; P = .043).

Conclusions
Intraoperative ICG angiography does not directly minimize skin erosion or necrosis. However, compared to gross examination alone, it enables surgeons to perform a more active debridement during surgery, thereby contributing to a lower incidence of advanced skin necrosis. In breast reconstruction, ICG angiography may be useful for assessing the viability of the postmastectomy skin flap and could contribute to successful reconstruction.

Level of Evidence
4
A Systematic Review of Outcomes and Complications of Tuberous Breast Surgery
Authors: Alvaro Anton I , Willet Jake W , Dounas George D , Jeeves Amy , Lodge Michelle , Javed Muhammad U 
Published: July 2023

Abstract

Background
Tuberous breast is a complex congenital breast anomaly that can be challenging to correct surgically.

Objectives
The authors conducted a systematic review with pooled analysis of data, with the aim of determining the effectiveness and complications related to operative management of the deformity.

Methods
Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines were adopted in performing this systematic review. A simplified classification system for tuberous breast deformity was developed to accurately compare data and guide analysis.

Results
The review identified 38 studies, reporting a total of 897 patients undergoing tuberous breast surgery. The mean age of patients was 24 years (range 13-53 years). Mean follow-up was 39 months. A combination of tissue rearrangement and implant augmentation was the most common technique (73% of patients) followed by fat transfer alone (9%). Breast implants were employed in 83% of patients. The mean implanted volume per breast was 263 cc. Fat grafting was performed in 13% of patients and mean volume of fat grafted per breast was 185 cc. An overall complication rate of 20% was reported. Subjective assessment of patient satisfaction was 99%, and the mean score on BREAST-Q for satisfaction with clinical outcome was 86.7. Future studies should focus on robust study designs including randomized and cohort studies, use of patient-reported outcome measures, and long-term follow-up.

Conclusions
The surgical techniques to correct tuberous breast deformity are safe, effective, and have a high satisfaction rate. Fat transfer has the capacity to provide promising results in treating tuberous breast deformity.

Level of Evidence: 4
Assessing the Efficacy of Hyperbaric Oxygen Therapy on Facelift Outcomes: A Case–Control Study Comparing Outcomes in Patients With and Without Hyperbaric Oxygen Therapy
Authors: Neel Omar Fouda , Mousa Ahmed Hafez , Al-Terkawi Reem Abdulmonem , Bakr Moamen M , Mortada Hatan 
Published: July 2023

Abstract

Background
Wound healing remains among the most concerning complications in aesthetic surgery. The use of hyperbaric oxygen therapy (HBOT) is an accepted method of supporting wound healing.

Objectives
The aim of this study is to assess the role of HBOT in postoperative healing and complication rates following facelift surgery.

Methods
This case–control study comprised facelift patients who received HBOT and those who did not between 2019 and 2022. Data were extracted from the patients’ medical records, with the primary outcomes being the presence of complications, wound-healing duration, and patient satisfaction.

Results
The authors recruited 20 female patients who underwent facelift for this study, with 9 patients in the HBOT group and 11 patients in the control group. The average number of HBOT sessions received was 7.22, and each session lasted an average of 78 ± 5 min. The duration of wound healing in the HBOT group ranged from 7 to 30 days (mean of 13.3 days), whereas the control group ranged from 6 to 90 days (mean of 36.9 days). This indicates a statistically significant shorter time to wound healing in the HBOT group compared to the control group (P &lt; .001).

Conclusions
Future prospective randomized controlled trials with larger sample sizes and blinding are needed to further evaluate the potential benefits of HBOT in the postoperative period. Nonetheless, our findings suggest that HBOT may be a promising adjunctive therapy for patients undergoing facelift surgery.

Level of Evidence: 3