bluuebunny/crossref_metadata_2025_split huggingface dataset:
Justice, Equity, and Inclusion in a School of Nursing: A Quality Improvement Program
Authors: Gona Clara M. , Pusey-Reid Eleonor , Reidy Patricia A. , Truong Kimberly A. , Tagliareni M. Elaine 
Published: January 2023

Background:
Despite the increased racial and ethnic diversity in the general population of the United States, the nursing workforce remains mostly White. Schools of nursing (SON) have increased recruitment and enrollment; however, students who represent racial and ethnic minoritized groups experience microaggressions, injustice, and social exclusion. This quality improvement program sought to equip faculty with skills to create a just and inclusive SON. The program was guided by the Institute for Healthcare's Model for Improvement.

Method:
Five workshops were developed and implemented during two semesters. Workshops were led and moderated by a diversity, equity, and inclusion consultant.

Results:
After the workshops, participants committed to create an inclusive environment, intervene when microaggressions occurred, implement curricular changes, and recognize themselves as members of a privileged group. Postworkshop discussions and reflections led to new initiatives in the SON.

Conclusion:

This faculty development program demonstrates programs to enhance justice, equity, and inclusion can be implemented successfully within SON.

[
J Nurs Educ
. 2023;62(1):20–27.]
Final-Year Nursing Students' Experiences During the COVID-19 Pandemic: A Scoping Review
Authors: El Hussein Mohamed Toufic , Dosani Aliyah , Al-Wadeiah Nada 
Published: January 2023

Background:
The transitional experience from final-year nursing students (FYNS) to newly graduated RNs (NGRN) challenges individuals' professional and personal identities. Multiple studies have documented the experiences of FYNS graduating in the pandemic, but no studies have synthesized the findings.

Method:
This scoping review examined the barriers and facilitators FYNS experience as they transitioned to become NGRN during the coronavirus disease 2019 (COVID-19) pandemic. Databases were searched for relevant articles, and articles published in peer-reviewed journals between 2019 and 2021 that focused on the support of FYNS in clinical settings in North America, Europe, and Australia were included.

Results:
Three themes were identified: emotional turmoil and coping, clinical competence and readiness for practice, and teaching strategies.

Conclusion:

This review revealed important insight on how the pandemic affected FYNS' transition to practice and identified gaps in the literature for future research.

[
J Nurs Educ
. 2023;62(1):6–11.]
L’intégration sociale des élèves de classe d’accueil : Une approche écologique
Authors: Richard Dominik 
Published: January 2023

J’ai construit cet article en m’appuyant sur mon expérience de recherche doctorale qui a mis en évidence l’importance d’adopter une approche écologique pour la compréhension par les enseignants titulaires de classe d’accueil du processus d’intégration sociale des élèves immigrants. Le but de cette recherche était de comprendre le phénomène d’appropriation du nouveau « milieu de vie » par une démarche permettant d’en montrer la face cachée et toute la complexité. La dimension compréhensive et collaborative de celle-ci s’est avérée fondamentale dans la démarche socio-constructiviste adoptée, « pour, par et avec » les participantes et l’enseignante du milieu d’accueil où s’est déroulée cette recherche. Les résultats indiquent, entre autres, que les élèves privilégient l’usage de stratégies d’appropriation à caractère transgressif par rapport à l’institution d’accueil. Le cadre scolaire, disposant de peu de moyens, a recours en effet à une démarche administrative d’intégration qui semble aller à l’encontre des principes appropriatifs. Dans ce contexte, la pratique théâtrale a pu contribuer à réduire l’écart ainsi créé en établissant une dynamique de socialisation horizontale entre les élèves et l’enseignante. À l’issue de cette recherche, je suis en mesure de suggérer aux établissements scolaires qui accueillent des élèves immigrants de diversifier les modalités de socialisation et d’institutionnaliser leur accueil dans une perspective trans-systémique en établissant, entre autres, un trialogue entre enseignants, élèves et familles. En guise de conclusion, j’apporterai quelques éléments de réponse à la question suivante : ce projet de recherche s’inscrit-il dans une optique d’éducation relative à l’environnement ?
Nicolas Laurence, La contestation portée par les innovations monétaires comme moteur de changement institutionnel. Le cas des monnaies locales et des cryptomonnaies
Authors: Laurence Nicolas 
Published: January 2023

Certaines innovations monétaires portent en elles une contestation du système monétaire existant. Les monnaies locales et les cryptomonnaies participent à cette dynamique. Les monnaies locales véhiculent une contestation monétaire axée sur les aspects sociaux et l’écologie à l’échelon territorial et local, alors que les cryptomonnaies, dont le Bitcoin est l’initiative la plus emblématique, remettent en cause le système monétaire en proposant des alternatives transnationales grâce à une technologie – la blockchain. La thèse vise à démontrer que ces deux innovations monétaires radicalement différentes véhiculent des projets politiques alternatifs qui participent à un même processus d’émergence de nouveaux espaces monétaires potentiellement porteurs de changement institutionnel.La contestation portée par ces innovations monétaires est d’abord saisie dans sa dimension discursive, avant d’être analysée à travers des entretiens semi-directifs et des actes juridiques, lorsqu’elle prend la forme d’actions collectives. Le recours à une économie politique de la monnaie nous permet de questionner la place des rapports de force et des conflits dans le processus de changement de l’institution monétaire.
Le rôle des acteurs de la société civile dans le déploiement des projets économiques et politiques alternatifs : l’expérience mexicaine de la 4T
Authors: Bertoli Max-Amaury , Morvant-Roux Solène , Bizberg Ilán 
Published: January 2023

Alors qu’en 2018, la vague d’indignation causée par les décennies de politiques néolibérales et corporatistes se fédère autour du projet de réforme d’Andrés Manuel López Obrador, les mesures mises en place par le nouveau président mexicain rompent rapidement sa promesse post-néolibérale. En effet, l’imposition de l’austérité républicaine, la centralisation opérationnelle de l’appareil public et la négation des organisations de la société civile sur lesquelles se base le nouveau gouvernement, toutes justifiées par la lutte contre la corruption, réduisent fortement sa portée transformatrice. À partir d’une approche socio-économique articulant différentes échelles d’analyse, cet article propose un regard critique sur les traits principaux de ce projet politique à travers l’étude d’un de ses programmes publics phares : Sembrando Vida. Malgré une approche agroécologique innovante, nous montrons que ce programme tombe dans une vision réductrice et homogénéisante des territoires et des communautés en refusant de prendre en compte le rôle primordial de la réciprocité, de la solidarité horizontale et des dynamiques collectives préexistantes, au même titre que la politique générale de López Obrador, tous deux ne parvenant pas à sortir d’une opposition stérile entre l’État et le Marché.
Crises, informalité et reconfigurations du marché du travail : quatre décennies de bouleversements économiques au Brésil
Authors: Razafindrakoto Mireille , Roubaud François , Saludjian Alexis 
Published: January 2023

Cet article analyse les ajustements du marché du travail brésilien sur longue période, notamment lors des épisodes de crise macroéconomique, qui s’étendent sur plus du tiers des quarante dernières années. L’un des objectifs est de soumettre les différentes théories de l’informel à l’épreuve des faits, et tout particulièrement l’hypothèse du rôle anticyclique que lui attribue la thèse dualiste. Sur le plan empirique, notre approche est basée sur un important travail d’« archéologie statistique » de reconstitution de séries historiques et de traitement de première main de millions d’observations de microdonnées d’enquêtes ou de registres administratifs. Les trois angles d’analyse adoptés convergent. Nous montrons entre autres la formidable résilience du marché du travail brésilien qui s’inscrit dans l’histoire et les disparitions progressives depuis les années 1990 des mécanismes de la crise « canonique », supplantée par un processus d’exclusion multiforme, et des frontières entre formel et informel, en défaveur des droits des travailleurs. Cependant, les crises ne sont pas toujours le meilleur point d’observation : la phase de croissance des années 2000, par exemple, apparaît comme la seule période « transformative » qui a laissé une empreinte positive et durable sur le monde du travail.
Performance et rareté des coopératives de travailleurs : contributions empiriques à partir du cas français (Scop)
Authors: Mirabel Thibault 
Published: January 2023

La thèse compare la performance des coopératives de travailleurs (Scop) et des entreprises conventionnelles. Ces deux types d’entreprise diffèrent par leur distribution des droits de propriété et leur mode de gouvernance. Au sein des Scop, les travailleurs ont le contrôle ultime de leur entreprise, tandis qu’au sein des entreprises conventionnelles, les investisseurs ont ce contrôle. Les Scop instituent la démocratie dans le monde économique. Malgré leur attractivité, elles représentent une fraction minuscule des entreprises dans le monde (2 400 en France). Cette thèse entend apporter des éléments nouveaux pour comprendre la rareté des Scop. Le chapitre 1 montre que la probabilité de créer une Scop est maximale lorsque le coût irrécupérable en travail est dominant et que le coût irrécupérable en capital est négligeable. Le chapitre 2 montre que les Scop survivent plus longtemps que les entreprises conventionnelles, indépendamment du fait que leurs ressources à l’entrée diffèrent ou non. Le chapitre 3 montre que les reprises en Scop, même d’entreprises en difficulté, survivent plus longtemps que les Scop nouvellement créées. Dans l’ensemble, cette thèse suggère que la rareté des Scop est due à des barrières à l’entrée spécifiques aux Scop, plutôt qu’à leur prétendue moindre performance vis-à-vis des entreprises conventionnelles.
Concomitant Hodgkin’s Lymphoma in a Patient with Tuberculous Spondylitis
Authors: Reddy Ravikanth 
Published: January 2023

Abstract
Concomitant Hodgkin’s lymphoma with tuberculosis is an exceedingly rare clinical scenario and a condition that is difficult to manage due to similar clinical presentation. This case report describes the same in a 44-year-old male patient diagnosed with Koch’s and initiated on antituberculosis therapy, based on confirmation of findings from the spine biopsy and culture. The patient’s clinical condition worsened despite being on treatment for tuberculosis. Hence, further work up of the patient was done which included mediastinoscopy and endobronchial ultrasound. Biopsy samples from a conglomerate mass in the lower cervical region and mediastinum revealed Hodgkin’s lymphoma of the nodular sclerosis type. This time, the patient showed significant improvement following treatment with chemotherapy and radiotherapy along with antituberculosis therapy.
Utility of Hematological and Biochemical Parameters as a Screening Tool for Assessing Coronavirus Disease 2019 Infection and its Severity
Authors: Alam Sana , Khan Sabina , Jain Vineet , Kashyap Varun , Kapur Prem 
Published: January 2023

Abstract

Background:
The rapidly evolving pandemic of Coronavirus disease 2019 (COVID-19) has presented with clinical severity, which varies from asymptomatic cases to being fatal in others. The need of the hour is to find meaningful and cost-effective COVID-19 biomarkers out of conventional hematological and biochemical parameters, which will help in the early identification of patients with a poor prognosis, leading to timely intervention.

Aim:
The aim was to analyze different biochemical and hematological parameters in COVID-19 patients and also to study the association of these parameters with disease severity.

Materials and Methods:
Cross-sectional observational study was carried out on 100 COVID-19 patients from a hospital from July to October 2020. Based on saturation of oxygen (SpO2), admitted patients were grouped into mild–moderate (SpO2 ≥90%) and severe groups (SpO2 <90%). Hematological and biochemical parameters were studied in both groups, and association with disease severity was analyzed.

Results:
Out of 100 patients, 57 patients were seen in the mild–moderate group (SpO2 ≥90%), while 43 patients (SpO2 <90%) belonged to the severe category. Males were predominant in both mild–moderate and severe groups. Among the hematological parameters, statistically significant higher values of absolute neutrophil count (P = 0.046) and significantly lower absolute lymphocyte count (P = 0.003) values were observed. With regard to biochemical parameters, increased urea and decreased total protein were found in the severe category and this association was statistically significant.

Conclusion:
To conclude, early identification and monitoring of hematological and biochemical parameters, especially those associated with higher disease severity, may contribute toward improving disease outcomes.
Cell of Origin Classification of Diffuse Large B-Cell Lymphoma
Authors: Dhar Lity , Singh Sarika , Jain Shyam Lata , Vindal Anubhav , Sinha Pallavi , Gautam Rashmi 
Published: January 2023

Abstract

Context:
Diffuse large B-cell lymphoma (DLBCL) is a neoplasm of medium-to-large B lymphoid cells with diffuse growth patterns. Although it is a potentially curable disease, around 40% of the cases are either refractory to primary treatment or relapse. Based on gene expression profiling (GEP), DLBCL can be classified as germinal center B-cell subtype (GCB) and activated B-cell subtype (ABC). About 10%–15% of cases do not convincingly fall into either of the two subtypes and hence remain unclassified. Most widely used and suggested by WHO is Hans algorithm comprising immunohistochemical markers CD10, B-cell lymphoma6 (BCL6), and IRF4/MUM1, which classifies CD10+ and CD10-/BCL6+/MUM1-DLBCL as GCB, while CD10-/BCL6+/MUM1 + and BCL6-DLBCL as non-GCB.

Aims:
The aim of this study was to classify DLBCL into GCB and non-GCB subtypes using Hans Algorithm.

Settings and Design:
This was a retrospective study.

Materials and Methods:
Twenty-eight histologically diagnosed cases of nodal (71.4%), as well as extranodal (28.6%) DLBCL, were taken over the period of 2 years with age ranging between 10 and 65 years with 19 males and 9 females. M: F = 2.1:1. Depending upon the site involved, a primary panel of immunohistochemistry (IHC) markers, namely CD20, CD3, LCA, EMA, and CK, followed by a secondary panel comprising CD10, CD19, CD30, LMP1, BCL2, BCL6, MUM1, MYC, and FOXP1 was used.

Results:
In this study, it was found that the non-GCB subtype was more common than the GCB subtype in Indian population.

Conclusions:
Although the gold standard of GEP to assign cells of origin is using RNA microarray analysis, however, due to resource constraints and other limitations such as long turnaround times, IHC is the next acceptable alternative.
Giant Placental Chorioangioma in a Young Patient Causing Adverse Fetal Outcome
Authors: Wadhwa Shagun , Dixit Sonali , Sharma Sonal 
Published: January 2023

Abstract
Chorioangiomas are benign vascular tumors of the placenta originating from chorionic tissue. They are also known as hemangiomas of the placenta. They occur in approximately 0.5%–1% of all pregnancies. Large chorioangiomas are rare and may lead to serious fetal and maternal complications. Here, we are describing a case of giant placental chorioangioma in a 19-year-old young female (G2A1) who presented to us at 39 weeks of gestation with decreased fetal movements. Ultrasound examination revealed an enlarged placenta with a well-defined 9.4 cm × 9.3 cm heteroechoic area with increased vascularity. Cesarean section was performed in view of fetal distress and a female baby weighing 1.6 kg was delivered. The newborn died within 2 weeks due to pulmonary hypoplasia and hemodynamic failure. The diagnosis of chorioangioma was confirmed with histopathology. This case depicts the necessity of early diagnosis, close fetal monitoring, and timely intervention in achieving a favorable pregnancy outcome.
Dendritic Cell-Based Immunity: Screening of Dendritic Cell Subsets in Breast Cancer-Bearing Mice
Authors: Aldahlawi Alia M , Zaher Kawther Sayed Ali 
Published: January 2023

Abstract

Background:
Breast cancer (BC) is the most devastating disease, particularly the lethal invasive form. It is the most underlying cause of death among women worldwide. The expansion of BC is controlled by a variety of alterations in the tumor cells themselves, in addition to the state of the immune system, which has a direct influence on the tumor microenvironment. Numerous receptors expressed by T-cells interact with ligands on antigen-presenting cells to provide activation signals results in mounting effector anti-tumor T-cell responses. On the other hand, there is a dearth of information about the actual interactions and reactions of T-cells and dendritic cells (DCs) all through the progression of tumor development.

Aim:
Immune system response against BC was investigated through tumor induction in mice. The size and volume of the tumor were calculated. Moreover, the phenotypical profile of T-cells and DCs from lymph nodes (LN) and spleens of BC-bearing mice was investigated. In addition, the levels of Transforming growth factor-β, Interferon-gamma (IFN-γ), Interleukin IL-2, IL-10, IL-4, IL-12, and tumor necrosis factor (TNF)-α were determined.

Materials and Methods:
MDA231 cells were utilized to induce BC in 30 white BALB/C mice, whereas the other 30 mice acted as healthy controls and were not treated with any cancer-causing agents. The impact of malignancy was evaluated using flow cytometry based on the marking surface molecules, as well as the titer of specific cytokines of the mice’s LN culture using the ELISA method. These cytokines included transforming growth factor-β (TGF-β), IFN-γ, IL-2, IL -10, IL -4, IL -12, and TNF-α.

Results:
The findings showed that the maturation of DCs was inhibited, followed by an accumulation of immature DCs. These immature DCs increase the release of TGF-β and cytokines like IL-10 and inhibit the release of IFN-γ and IL-12 in the culture supernatant of nodal lymph and spleen suspension of BC-bearing mice compared to control. In addition, there was a low expression of CD80 and CD86 on DCs, which indicates a low maturation process.

Conclusion:
According to the findings, the tumor microenvironment may have been responsible for preventing the maturation of DCs. This, in turn, weakened the immune response and facilitated the ability of the tumor to proliferate. Furthermore, the tumor microenvironment increased the number of immature DCs by inhibiting their stimulation by overexpression of TGF-β-produced by regulatory T lymphocytes and stimulation of tumor cells. In addition, the tumor microenvironment stimulated the secretion of cytokines such as IL-10, and CD4 and decreased the secretion of IFN-γ-and IL-12 in tumor-induced mice cultured LN and spleen.
Edaravone Oral Suspension (Radicava)
Authors: CADTH  
Published: January 2023

CADTH recommends that Radicava should be reimbursed by public drug plans for the treatment of patients with amyotrophic lateral sclerosis (ALS), if certain conditions are met.
Radicava oral suspension should only be covered to treat patients with ALS provided that it is covered for a similar patient population and in a similar way to the IV formulation of Radicava for the treatment of adult patients with ALS.
Radicava oral suspension should only be reimbursed if prescribed in a similar manner as the IV formulation of Radicava is prescribed, and that the cost of Radicava oral suspension does not exceed the drug program cost of IV formulation of Radicava.
O passado como distração
Authors: H. de Faria Pereira Mateus , Lopes de Araujo Valdei 
Published: January 2023

Neste ensaio analisamos como o movimento populista encarnado por Bolsonaro se engaja com a história de uma forma que ativa sua base política heterogênea. Esses engajamentos parecem ser diferentes de alguns aspectos das cronossofias modernas, como o abandono da sincronização e a apresentação coerente de uma história nacional. Em vez disso, a nova historicidade populista da extrema direita brasileira se baseia mais no apego afetivo, uma performance histórica pragmática e altamente fragmentada que, como defendemos, mais se assemelha a uma historicidade que chamamos de “atualismo”. Para demonstrar a afinidade que vemos entre essa historicidade chamada de atualismo e a versão específica bolsonarista do chamado neopopulismo, este artigo está dividido em três partes. Primeiro, apresentamos o conceito e a teoria do atualismo. Em seguida, caracterizamos as dimensões neopopulistas do bolsonarismo, ou seja, o movimento cultural e político representado por Jair Bolsonaro. Por fim, analisamos o novo populismo brasileiro em seus engajamentos com a história, especialmente as atuações da história pelos três secretários de cultura do governo Bolsonaro e como a desfactualização da realidade ganha força, criando as condições de possibilidade de o passado ser como um grande guarda-roupa cheio de imagens e modelos de prêt-à-porter.
Развитие методического инструментария оценки и выбора высокотехнологичных инвестиционных проектов в рамках научно-образовательных центров (НОЦ) мирового уровня
Authors: Лавриненко Елена Александровна , Бондарева Яна Юрьевна , Лыщикова Юлия Владимировна 
Published: January 2023

В сложившихся условиях значительную актуальность приобретает интенсификация процессов импортозамещения, особенно в высокотехнологичных сферах и секторах экономики. При этом реализация венчурных инвестиционных проектов в области развития высоких технологий связана со значительными и высокорисковыми инвестиционными затратами, а также необходимостью согласования интересов широкого круга стейкхолдеров проекта, таких как индустриальные партнеры, органы государственной власти и разнообразные институты развития. Несмотря на то, что создаваемые в России с 2019 года научно-образовательные центры (НОЦ) мирового уровня способствуют генерации большого числа качественных научных идей, на данный момент отсутствуют четкие методические рекомендации по отбору высокотехнологичных проектов в рамках НОЦ, что и определяет актуальность темы исследования. В статье авторами представлена дорожная карта отбора и реализации высокотехнологичных инвестиционных проектов. В развитие методического инструментария оценки и выбора высокотехнологичных инвестиционных проектов разработана скоринговая модель отбора проектов, представляющая собой набор критериев, в соответствии с которыми происходит оценка проектов и им присваиваются баллы, которые после суммирования позволяют отнести проект к одному из трех представленных классов.
Благодарности: исследование выполнено в рамках государственного задания НИУ «БелГУ» FZWG-2020-0016, тема проекта «Фундаментальные основы глобальной территориально-отраслевой специализации в условиях цифровизации и конвергенции технологий».