bluuebunny/crossref_metadata_2025_split huggingface dataset:
The pathway from sensory processing sensitivity to physical health: Stress as a mediator
Authors: Kenemore Jordan , Chavez Juliana , Benham Grant 
Published: April 2023

AbstractSensory processing sensitivity (SPS) has been proposed as an innate trait associated with differences in the processing and reactivity to internal and external stimuli. To date, there has been limited research on the association between SPS and physical health and only one study examining mediators of this relationship. The aim of this study was to examine psychological stress as a mediator of the SPS‐health relationship in a predominately Hispanic sample of 923 adult undergraduates attending university between 2018 and 2020. We identified three SPS factors, each of which were associated with poorer physical health as assessed through two psychometrically validated self‐report measures of physical symptoms. Additionally, we demonstrate that this relationship is mediated by perceived stress, suggesting that treatments focussed on stress reduction might be an avenue through which the impact of SPS on physical health can be modified.
Dual‐Functional Super‐Assembled Mesoporous Carbon‐Titania/AAO Hetero‐Channels for Bidirectionally Photo‐Regulated Ion Transport
Authors: Zhou Shan , Zhang Xin , Xie Lei , He Yanjun , Yan Miao , Liu Tianyi , Zeng Hui , Jiang Lei , Kong Biao 
Published: April 2023

AbstractPhoto‐regulated nanofluidic devices have attracted great attention in recent years due to their adjustable ion transport in real time. However, most of the photo‐responsive nanofluidic devices can only adjust the ionic current unidirectionally, and cannot simultaneously increase or decrease the current signal intelligently by one device. Herein, a mesoporous carbon‐titania/ anodized aluminum hetero‐channels (MCT/AAO) is constructed by super‐assembly strategy, which exhibits dual‐function of cation selectivity and photo response. The polymer and TiO2 nanocrystals jointly build the MCT framework. Polymer framework with abundant negatively charged sites endows MCT/AAO with excellent cation selectivity, and TiO2 nanocrystals are responsible for the photo‐regulated ion transport. High photo current densities of 1.8 mA m−2 (increase) and 1.2 mA m−2 (decrease) are realized by MCT/AAO benefiting from the ordered hetero‐channels. Significantly, MCT/AAO can also achieve the bidirectionally adjustable osmotic energy by alternating the configurations of concentration gradient. Theoretical and experimental results reveal that the superior photo‐generated potential is responsible for the bidirectionally adjustable ion transport. Consequently, MCT/AAO performs the function of harvesting ionic energy from the equilibrium electrolyte solution, which greatly expands its practical application field. This work provides a new strategy in constructing dual‐functional hetero‐channels toward bidirectionally photo‐regulated ionic transport and energy harvesting.
Stabilizing Liquid in Precise Nonequilibrium Shapes via Fast Interfacial Polymerization
Authors: Lian Xiaodong , Liao Shenglong , Han Wenwen , Song Chenhao , Wang Yapei 
Published: April 2023

AbstractDue to the minimization of interface area caused by surface tension, the stabilization of liquid in complex and precise nonequilibrium shapes is challenging. In this work, a simple, surfactant‐free, and covalent strategy to stabilize liquid in precise nonequilibrium shapes via fast interfacial polymerization (FIP) of highly reactive n‐butyl cyanoacrylate (BCA) monomer triggered by water‐soluble nucleophiles is described. Full interfacial coverage can be achieved instantly, and the resultant polyBCA film anchored at the interface can support the unequal interface stress, which allows the production of non‐spherical droplets with complex shapes. Notably, the formulation of internal aqueous phase is nearly unaffected since no specific additive is required. Moreover, considering the excellent biocompatibility of BCA and polyBCA, the produced droplets can be used as micro‐bioreactor for enzyme catalysis and even bacterial culture, which well mimic the morphology of cells and bacteria to achieve the biochemical reaction in non‐spherical droplets. The present work not only opens a new sight for the stabilization of liquid in nonequilibrium shapes, but may also promote the development of synthetic biology based on non‐spherical droplets, and tremendous potential applications are anticipated.
Sodium Stoichiometry Tuning of the Biphasic‐NaxMnO2 Cathode for High‐Performance Sodium‐Ion Batteries
Authors: Zhang Yiming , Tang Dafu , Liu Yuanyuan , Wang Jin , Li Zhipeng , Li Xin , Han Guang , Wei Qiulong , Qu Baihua 
Published: April 2023

AbstractSodium‐ion batteries (SIBs) are promising alternatives for large‐scale energy storage owing to the rich resource and cost effectiveness. However, there are limitations of suitable low‐cost, high‐rate cathode materials for fast charging and high‐power delivery in grid systems. Herein, a biphasic tunnel/layered 0.80Na0.44MnO2/0.20Na0.70MnO2 (80T/20L) cathode delivering exceptional rate performance through subtly regulating the sodium and manganese stoichiometry is reported. It delivers a reversible capacity of 87 mAh g−1 at 4 A g−1 (33 C), much higher than that of tunnel Na0.44MnO2 (72 mAh g−1) and layered Na0.70MnO2 (36 mAh g−1). It proves that the one‐pot synthesized 80T/20L is able to suppress the deactivation of L‐Na0.70MnO2 under air‐exposure, which improves the specific capacity and cycling stability. Based on electrochemical kinetics analysis, the electrochemical storage of 80T/20L is mainly based on pseudocapacitive surface‐controlled process. The thick film of 80T/20L cathode (a single‐side mass loading over 10 mg cm−2) also has superior properties of pseudocapacitive response (over 83.5% at a low sweep rate of 1 mV s−1) and excellent rate performance. In this sense, the 80T/20L cathode with outstanding comprehensive performance could meet the requirements of high‐performance SIBs.
Effective Surface Modification of 2D MXene toward Thermal Energy Conversion and Management
Authors: Bark Hyunwoo , Thangavel Gurunathan , Liu Rui Jun , Chua Daniel H. C. , Lee Pooi See 
Published: April 2023

AbstractThermal energy management is a crucial aspect of many research developments, such as hybrid and soft electronics, aerospace, and electric vehicles. The selection of materials is of critical importance in these applications to manage thermal energy effectively. From this perspective, MXene, a new type of 2D material, has attracted considerable attention in thermal energy management, including thermal conduction and conversion, owing to its unique electrical and thermal properties. However, tailored surface modification of 2D MXenes is required to meet the application requirements or overcome specific limitations. Herein, a comprehensive review of surface modification of 2D MXenes for thermal energy management is discussed. First, this work discusses the current progress in the surface modification of 2D MXenes, including termination with functional groups, small‐molecule organic compound functionalization, and polymer modification and composites. Subsequently, an in situ analysis of surface‐modified 2D MXenes is presented. This is followed by an overview of the recent progress in the thermal energy management of 2D MXenes and their composites, such as Joule heating, heat dissipation, thermoelectric energy conversion, and photothermal conversion. Finally, some challenges facing the application of 2D MXenes are discussed, and an outlook on surface‐modified 2D MXenes is provided.
Wordless but not silent: Unlocking the power of wordless picture books
Authors: Honaker Jennifer D. , Miller Ryan T. 
Published: April 2023

AbstractTeaching literacy skills that require critical reading and linguistic output can feel like an insurmountable challenge when presented with students of varying language proficiencies. One valuable but often unused tool to surmount these challenges is wordless picture books (WPBs). WPBs can be used to develop literacy skills more equitably among learners with varying language proficiencies, even when in class with native‐speaking peers. They transcend language and cultural barriers often found in traditional literature and can be a tool for exploring multicultural perspectives. However, WPBs are often underrated and misunderstood by teachers and students, and frequently relegated to classrooms with young, pre‐emergent readers. We argue for the power of WPBs for literacy development among English learners (ELs) of all ages by addressing common misconceptions, highlighting unique benefits of WPBs to ELs, and suggesting practical pedagogical implications.
Diagnosis and treatment of a novel Mycobacterium haemophilum associated pneumonia in an African pygmy hedgehog (Atelerix albiventris)
Authors: Vecere Gina , Malka Shachar , Garner Michael M. , Dennison Sophie , Sanchez Susan 
Published: April 2023

AbstractAn unknown age (at least 1.5‐year old), male, entire African pygmy hedgehog (Atelerix albiventris) was presented for decreased appetite, lethargy and laboured breathing. Pulmonary radiographic lesions consistent with pneumonia were noted in serial computed tomography scans. The hedgehog initially responded well to treatment with azithromycin and orbifloxacin for several months, but its health declined upon discontinuation of treatment. After continued decline despite resumed antibiotic therapy, the patient was humanely euthanised. A postmortem examination was performed, and histologic examination identified severe granulomatous bronchointerstitial pneumonia with intralesional acid‐fast staining bacteria. Samples from the lung and liver were positive for Mycobacterium haemophilum by PCR and further DNA sequencing. This report describes the clinical presentation, diagnosis, treatment and outcome of a pulmonary infection caused by M. haemophilum in a hedgehog.
Intelligent Bayesian regularization‐based solution predictive procedure for hybrid nanoparticles of AA7072‐AA7075 oxide movement across a porous medium
Authors: Awan Saeed Ehsan , Ali Faizan , Awais Muhammad , Shoaib Muhammad , Raja Muhammad Asif Zahoor 
Published: April 2023

AbstractThe research community has shown great interest for investigation in the nanofluids models involving Aluminum Alloys AA7072 and AA7072 +AA7075 due to their advantageous impact on heat transfer, physical and mechanical characteristic exploiting in broad engineering applications such as manufacturing of spacecraft, aircraft parts and building testing. The hybrid nanomaterial AA7072‐AA7075 based fluidic system is investigated in this paper using an artificial neural network with Bayesian regularization scheme (ANNs‐BRS). The derived partial differential equations (PDEs) are transformed into ordinary differential equations system ODEs and obtained the reference datasets for the estimated solution dynamics of hybrid nanofluidic system. For prominent parameters, the influence of flow on the temperature distribution and velocity plot are investigated. The performance on 80% training samples, 5% testing and 15% validation dataset for ANNs‐BRS is well‐established in terms of error histogram plots, regression analysis, and MSE based statistics. The results for entropy generation, Eckert number Ec, magnetic interaction parameter M, suction parameter S, and heat generation parameter Q are also discussed. The results show that the Eckert number Ec has the effect of slowing down the rate of heat transfer while increasing the temperature and increases in suction parameter causes decrease in temperature while increase in temperature profile due to enhancement of suction parameter.
Adenoide Vegetationen – Diagnostik und Therapie – die neue S2k-Leitlinie
Authors: Ahmad Z. , Krüger K. , Lautermann J. , Lippert B. , Tenenbaum T. , Tigges M. , Tisch M. 
Published: April 2023

ZusammenfassungEine Hyperplasie der Tonsilla pharyngealis ist als Erkrankung zu bewerten, wenn durch mechanische Obstruktion und/oder chronische Entzündungen des Nasenrachens Krankheitssymptome auftreten. Aus einer chronischen Tubenventilationsstörung können unterschiedliche Mittelohrerkrankungen wie Schallleitungsschwerhörigkeit, Cholesteatom und rezidivierende akute Otitis media entstehen. Während der Inspektion ist das Augenmerk auf das Vorliegen einer Facies adenoidea mit dauerhaft offenem Mund und sichtbarer Zungenspitze zu legen. Bei starken Beschwerden und/oder frustranen konservativen Therapieversuchen erfolgt die Adenotomie in der Regel ambulant. Die herkömmliche Kürettage gilt nach wie vor als etablierte Standardmethode in Deutschland. Bei klinischen Hinweisen auf Mukopolysaccharidose ist die histologische Untersuchung indiziert. Wegen des Blutungsrisikos wird auf den Gerinnungsfragebogen, der obligat vor jedem operativen Eingriff im Kindesalter durchzuführen ist, hingewiesen. Trotz ordnungsgemäßer Adenotomie kann es zu einem Rezidiv der adenoiden Vegetationen kommen. Vor Entlassung in das häusliche Umfeld sollte eine HNO-ärztliche Kontrolle durch Inspektion des Rachens auf Nachblutung und eine anästhesiologische Freigabe erfolgen.
Depletion of abundant plasma proteins for extracellular vesicle proteome characterization: benefits and pitfalls
Authors: Reymond Sandrine , Gruaz Lyssia , Sanchez Jean-Charles 
Published: April 2023

AbstractBlood extracellular vesicles (EVs) play essential roles in cell–cell communication and their molecular cargo is a promising source of disease biomarkers. However, proteomic characterization of plasma-derived EVs is challenged by the presence of highly abundant plasma proteins, which limits the detection of less abundant proteins, and by the low number of EVs in biological fluids. The aim of this study was to investigate if the removal of abundant plasma proteins prior to EV isolation could improve plasma-derived EV characterization by LC–MS/MS and expand the proteome coverage. Plasma depletion was performed using a single-use spin column and EVs were isolated from only 100 µL of non-depleted and depleted plasma by size exclusion chromatography. Afterwards, EVs were characterized by nanoparticle tracking analysis and mass spectrometry–based proteomics using a data-independent acquisition approach. Depleted plasma-derived EVs had higher particle concentrations and particle-to-protein ratios. Depletion did increase the protein coverage with a higher number of identifications in EVs from depleted plasma (474 proteins) than from non-depleted (386 proteins). However, EVs derived from non-depleted plasma carried a slightly higher number of common EV markers. Overall, our findings suggest that plasma depletion prior to EV isolation by size exclusion chromatography provides higher yield and protein coverage, but slightly lower identification of EV markers. This study also showed the possibility to characterize the proteome of EVs derived from small plasma volumes, encouraging the clinical feasibility of the discovery of EV biomarkers.
Clinical outcomes and survival comparison between NexGen all-poly and its metal-backed equivalent in total knee arthroplasty
Authors: Apostolopoulos Vasileios , Nachtnebl Luboš , Mahdal Michal , Pazourek Lukáš , Boháč Petr , Janíček Pavel , Tomáš Tomáš 
Published: April 2023

Abstract

Purpose
This study aims to compare total knee replacement (TKA) with NexGen All-Poly (APT) and NexGen Metal-Backed (MBT) in terms of implant survivorship, reasons leading to implant failure and functional results of defined age categories.

Methods
A single-centre, retrospective evaluation of 812 patients who underwent knee replacement with NexGen CR between 2005 and 2021, comparing a modern congruent APT component to a modular MBT equivalent component using a similar surgical technique at a notable mean follow-up duration. Implant survival, functional outcomes using the Knee Society Score and range of motion were evaluated and compared in different age categories.

Results
Of the 812 NexGen CR TKAs performed at our institution, 410 (50.4%) used APT components and 402 (49.6%) MBT components. The survival rate of NexGen APT was 97.1% and that of NexGen MBT was 93.2% (p = 0.36). Removal of the implant occurred overall in 15 cases, for MBT in ten cases, and for APT in four cases. The FS was proved to be significantly higher when APT components were implanted in younger patients than for MBT (p = 0.005). A similar range of motion between the components was recorded (p = 0.1926).

Conclusion
Under defined conditions, we measured the clinical results of implants from a single manufacturer implanted in a single department using a similar surgical technique. Considering the limitations, we suggest that all-polyethylene tibial components are equal or even superior to metal-backed ones across the examined age categories.
Quantitative Analysis of Temporal Parameters Correlated with Aspiration and Lesion Location in Stroke Patients
Authors: Kim Jeong Min , Park Ji Eun , Baek Seung Jun , Yang Seung Nam 
Published: April 2023

AbstractThe purpose of this study was to identify differences in temporal parameters correlating to the presence of aspiration and the severity of penetration-aspiration scale (PAS) in patients with dysphagia after stroke. We also investigated whether there was a significant difference in temporal parameters based on the location of the stroke lesion. A total of 91 patient videofluoroscopic swallowing study (VFSS) videos of stroke patients with dysphagia were retrospectively analyzed. Various temporal parameters including oral phase duration, pharyngeal delay time, pharyngeal response time, pharyngeal transit time, laryngeal vestibule closure reaction time, laryngeal vestibule closure duration, upper esophageal sphincter opening duration and upper esophageal sphincter reaction time were measured. Subjects were grouped by the presence of aspiration, PAS score, and location of the stroke lesion. Pharyngeal response time, laryngeal vestibule closure duration, and upper esophageal sphincter opening duration were significantly prolonged in the aspiration group. These three factors showed positive correlation with PAS. In terms of stroke lesion, oral phase duration was significantly prolonged in the supratentorial lesion group, while upper esophageal sphincter opening duration was significantly prolonged in the infratentorial lesion group. We have demonstrated that quantitative temporal analysis of VFSS can be a clinically valuable tool identifying dysphagia pattern associated with stroke lesion or aspiration risk.
“The communication I had with him back then is still stuck in my mind.” Bereaved families of cancer patients’ experiences for end-of-life communication
Authors: Jeon Heejung , Kim Sanghee , Lee Ilhak 
Published: April 2023

Abstract
Purpose
Communication with family members is important to end-of-life care for patients with cancer. It is an interactive engagement between terminally-ill cancer patients and their families through which they expand their mutual understanding to cope with losses and find meaning in death. This study aimed to describe the experiences of end-of-life communication between patients with cancer and their family members in South Korea.

Methods
This is a qualitative descriptive study using in-depth semi-structured interviews. Ten bereaved family members with end-of-life communication experience with terminal cancer patients were recruited through purposive sampling. Data were analyzed using qualitative content analysis.

Results
A total of 29 constructed meanings, 11 sub-categories, and the following 3 categories were derived: “Offering a space for patients to reminisce and reflect,” “Building a bond,” and “Reflections on what we need.” End-of-life communication primarily centered on the patients, with families struggling to share their stories with them. Although the families coped well, they also regretted the lack of meaningful communication with the patients, indicating a need for support to facilitate effective end-of-life communication.

Conclusion
The study highlighted concrete communication for finding meaning at the end-of-life for cancer patients and their families. We found that the families have the potential to communicate appropriately to cope with the patients’ end-of-life. Nevertheless, end-of-life presents a unique challenge in which families require adequate support. Given the increasing number of patients and families dealing with end-of-life care in hospitals, healthcare providers should be mindful of their needs and help them cope effectively.
Rapid or Immediate ART, HIV Stigma, Medical Mistrust, and Retention in Care: An Exploratory Mixed Methods Pilot Study
Authors: Mgbako Ofole , Loughran Claire , Mathu Rachel , Castor Delivette , McLean Jacob , Sobieszczyk Magdalena E. , Olender Susan , Gordon Peter , Lopez-Rios Javier , Remien Robert H. 
Published: April 2023

AbstractRapid or immediate antiretroviral therapy (iART) after HIV diagnosis improves linkage to care and time to viral suppression. However, iART may affect or be affected by HIV-related stigma and medical mistrust. In this mixed-methods pilot study, we examined the bi-directional role of HIV stigma, medical mistrust, and visit adherence (VA) in the context of iART in a diverse, newly diagnosed patient population. Participants were recruited from an HIV clinic in New York City and we utilized a convergent parallel design integrating quantitative data from demographic surveys, the HIV Stigma Survey (HIVSS), the Medical Mistrust Index (MMI) and electronic medical records, and qualitative data from in-depth interviews. Among the sample (N = 30), 26% (N = 8) initiated ART same-day or within 3 days, while the majority (N = 17) initiated between 4 and 30 days, and 17% (N = 5) initiated ART > 30 days. The median (range) age was 35, and most were English-speaking, Black or Hispanic men and identified as gay. Time to ART initiation was associated with time to linkage to care and time to viral suppression. Day 0–3 group’s major theme was iART as stigma prevention, and they had the highest mean HIVSS, lowest MMI score, and a visit adherence of 0.86. Day 4–30 group’s major theme was alleviation of internalized stigma, and they had the lowest mean HIVSS score, and highest visit adherence of 0.91. Day > 30 group’s major theme was exacerbation of perceived or anticipated stigma, had the highest MMI score and a visit adherence of 0.85. iART implementation requires equitable strategies that address HIV-stigma and mistrust.
Comprehensive In Vivo and In Vitro Studies for Evaluating the Bone-Bonding Ability of Na2O–CaO–SiO2–B2O3–Ag2O Glasses for Fracture Healing Applications
Authors: Youness Rasha A. , Amer Mohammed Said , Taha Mohammed A. 
Published: April 2023

AbstractIn the present investigation, Na2O–CaO–SiO2–B2O3–Ag2O glasses were prepared using the traditional melt-quenching process, with Ag2O content progressively raised from 0 to 4 wt.%, at the expense of B2O3, in the chemical composition of these glasses. The created glasses’ physical, mechanical and electrical characteristics were measured. The bone bonding capacity of the as-prepared specimens was evaluated not only by in vitro studies with treatment in simulated body fluid but also by in vivo studies using the albino rat model at different time intervals up to 28 days. The obtained findings revealed that increasing the Ag2O content gradually improved the fracture toughness of the samples by approximately 3.94, 11.84, 27.63, 50%, but fortunately with slight decreases in the microhardness, i.e. 1.02, 2.73, 8.90 and 16.43% and other mechanical properties. All samples had electrical conductivities of 2.36, 2.65, 2.84, 3.59, and 4.23 × 10‒5 S/m when the frequency was 1 MHz, compared to 1.36, 1.58, 1.72, 2.10, and 2.42 × 10‒4 S/m for the same samples at 20 MHz. Furthermore, the addition of Ag2O had a favorable function in improving the bioactivity of the glass samples, as evidenced by in vitro and in vivo data, and no cytotoxicity was seen. Based on these attractive findings, it is possible that the produced glass samples would be suitable for orthopedic applications at load-bearing-sites.
Graphical Abstract