bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Pilot study on thyroid status, lipid profile creatine kinase in human cardiac patients
Authors: Pancholi Boskey , Gautam Manish 
Published: February 2023

Background: The progression of Coronary Heart Disease (CHD) is linked to a multitude of comorbidities, such as thyroid dysfunction, dyslipidemia. Objectives were to determine the thyroid and serum lipid profile, cholesterol, triglycerides and creatin kinase profile of CHD patients and to establish correlation between severity of cardiac disease with these two metabolic parameters.
Methods: This was a prospective study conducted among 55 CHD patients over 1 year admitted in the department of cardiology, General Government Hospital, Bikaner.
Results: There are 66% male and 36% female patients among the 55 study cases. Majority of the patients (54/55) exhibited higher T3 concentration, whereas one patient has low T4 value accompanied by 14 patients with high TSH value. Three patients have higher value of cholesterol with 17 patients of higher triglycerides levels. Among the patients eleven demonstrated higher creatine kinase values.
Conclusions: The numbers of patients increasing with decreasing T3 and increasing thyroid stimulating hormone (TSH) proportionate to the severity of the cardiac failure. In addition, hypothyroidism is becoming more common in people with chronic cardiac disease. Serum triglycerides, LDL and HDL levels rise statistically significantly in CHD patients.
Keywords: Dyslipidemia, CHD, Cholesterol, triglycerides, TMB.
Transferosomes: A Novel Topical Approach
Authors: Kodi Shruti Rao , Reddy M. Sunitha 
Published: February 2023

Transdermal drug delivery technologies have gained attention in recent years due to their advantages over conventional drug delivery systems. Transdermal drug delivery is limited because the stratum corneum functions as a barrier. Transferosomes are ultradeformable vesicles consisting of a lipid bilayer with phospholipids and an edge activator. After topical treatment, transferosomes can deliver larger quantities of active ingredients to deeper skin layers than liposomes. Generally, molecules with a molecular weight of more than 500 Daltons cannot penetrate through skin. As a result, this route can only be used to give a few medications. Therefore, this issue can be solved by encapsulating the medicine in a transferosome. Drugs that are hydrophilic, lipophilic or amphiphilic can be enclosed in transferosomes, which have a bilayer structure and a higher penetration efficiency than traditional liposomes. The most prevalent lipid found in a cell membrane, phosphatidylcholine, is found in high concentrations in the majority of transferosomes. Surfactants including sodium deoxycholate, Tween 80, and span 80 are frequently utilized as edge activators since they increase skin tolerance and reduce the chance of unfavorable effects. Due to their elastic nature, transferosomes can bend and squeeze themselves as a complete vesicle through tiny pores that are much smaller than their size.
Keywords: Transferosomes, Transdermal drug delivery, stratum corneum
Pengaruh kualitas pelayanan dan produk terhadap kepuasan konsumen di the rice table indonesian restaurant desamuda villas seminyak bali
Authors: Heryana I Putu Agus , Aprinica Ni Putu Isha , Wardana Miko Andi 
Published: February 2023

Kepuasan konsumen menjadi hal penting terhadap kinerja hotel. Untuk itu dalam memperoleh kepuasan konsumen dapat dilihat dari jumlah penjualan produk dan kualitas dari suatu produk, serta tingkat kepuasan konsumen terhadap pelayanan. Kepuasan konsumen dipengaruhi oleh kualitas pelayanan dan kualitas produk yang dilakukan oleh karyawan baik waiter dan waitress dalam memberikan pelayanan kepada konsumen. Penelitian ini dilakukan di The Rice Table Indonesian Restaurant Desamuda Villas Seminyak Bali. Teknik yang digunakan dalam pengambilan sampel adalah proportionate stratified random sampling. Sampel yang digunakan adalah konsumen The Rice Table Indonesian Restaurant dengan jumlah sebenyak 50 responden. Metode penelitian yang digunakan adalah kuantitatif dengan IBM SPSS Statistics 24. Hasil dari penelitian ini menunjukkan bahwa: 1) Pengaruh kualitas pelayanan berpengaruh positif dan signifikan terhadap kepuasan konsumen. 2) Pengaruh kualitas produk berpengaruh positif dan signifikan terhadap kepuasan konsumen. Manfaat dari penelitian ini adalah untuk mengetahui kualitas pelayanan dan kualitas produk yang diberikan waiter atau waitress terhadap kepuasan konsumen.

Consumer satisfaction is important to hotel performance. For this reason, in obtaining consumer satisfaction, it can be seen from the number of product sales and the quality of a product, as well as the level of customer satisfaction with services. Consumer satisfaction is influenced by the quality of service and product quality carried out by employees both waiters and waitresses in providing services to consumers. This research was conducted at The Rice Table Indonesian Restaurant Desamuda Villas Seminyak Bali. The technique used in sampling is proportionate stratified random sampling. The sample used is the consumer of The Rice Table Indonesian Restaurant with a total of 50 respondents. The research method used is quantitative with IBM SPSS Statistics 24. The results of this study indicate that: 1) The effect of service quality has a positive and significant effect on customer satisfaction. 2) The effect of product quality has a positive and significant effect on consumer satisfaction. The benefit of this study is to determine the quality of service and product quality provided by the waiter or waitress on customer satisfaction.
Pengaruh pemahaman konsep standard operating procedure terhadap produktivitas kerja room service di melia bali hotel spa and resort
Authors: Sandinata I Wayan Raditya Wira , Purnantara I Made Hadi , Arnawa I Gst Made Suka 
Published: February 2023

Penelitian ini bertujuan untuk mengetahui pengaruh Standard Operating Procedure (SOP) terhadap Produktivitas Room service di Melia Bali Hotel SPA and Resorts. Penelitian dilakukan di Melia Bali Hotel SPA and Resorts dengan mengambil responden adalah karyawan bagian Food and Beverages Service. Penelitian dilakukan dengan menyebar kuesioner kepada karyawan. Teknik analisis yang digunakan untuk menganalisis data, yaitu analisis regresi linier sederhana, uji T, dan uji koefesien determinasi. Analisis regresi linier sederhana dilakukan untuk mengetahui ada atau tidaknya pengaruh SOP terhadap produktivitas kerja. Metode penelitian yang digunakan adalah statistik deskriptif kuantitatif. Hasil dari penelitian menunjukkan bahwa SOP berpengaruh positif dan signifikan terhadap produktivitas Room Service. Dalam peningkatan produktivitas karyawan alangkah baiknya pihak manejemen hotel tetap memberikan sosialisasi atau mengingatkan kepada karyawannya untuk lebih menerapkan Standard Operating Procedure sesuai dengan tujuan pihak organisasi dan manajemen

This study aims to determine the effect of Standard Operating Procedure (SOP) on Productivity Room service at Melia Bali Hotel SPA and Resorts. The research was conducted at Melia Bali Hotel SPA and Resorts by taking respondents who were employees of the Food and Beverages Service. The research was conducted by distributing questionnaires to employees. The analytical technique used to analyze the data, namely simple linear regression analysis, T test, and coefficient of determination test. Simple linear regression analysis was conducted to determine whether or not the influence of SOP on work productivity. The research method used is quantitative descriptive statistics. The results of the study indicate that SOP has a positive and significant effect on the productivity of Room Service. In increasing employee productivity, it would be better if the hotel management continued to provide socialization or remind employees to better implement Standard Operating Procedures in accordance with the goals of the organization and management.
Pengaruh brand image dan promosi traveloka terhadap minat beli kamar hotel di kabupaten badung
Authors: Sia Irena Eldryanti Ating , Yani Ni Wayan Mega Sari Apri , Susanti Luh Eka 
Published: February 2023

Kehadiran Online Travel Agent (OTA) memudahkan konsumen untuk mencari, membandingkan harga sampai akhirnya melakukan pemesanan kamar sebelum melakukan perjalanan wisata. Salah satu website yang berperan penting dalam industri pariwisata adalah Traveloka. Penelitian ini bertujuan untuk mengetahi pengaruh brand image dan promosi terhadap minat beli kamar hotel di Kabupaten Badung. Jenis sampling yang digunakan adalah non-probability sampling dengan teknik purposive sampling dengan jumlah sampel penelitian sebanyak 100 respoden. Teknik analisis menggunakan uji validitas, uji reabilitas, uji asumsi klasik, analisis regresi linear berganda, pengujian hipotesis melalui uji F dan uji T, serta analisis koefisien determinasi. Brand image dan promosi Traveloka berpengaruh positif dan signifikan terhadap minat beli kamar hotel di Kabupaten Badung dengan hasil F hitung secara simultan adalah sebesar 91,892 > F tabel = 3,09. Brand image berpengaruh positif dan signifikan terhadap minat beli kamar hotel di Kabupaten Badung dengan nilai t hitung sebesar 2,565 > t tabel = 1,661. Promosi Traveloka berpengaruh positif dan signifikan terhadap minat beli kamar hotel di Kabupaten Badung dengan diperoleh nilai t hitung sebesar 6,728 > t tabel = 1,661.

compare prices and finally make a room reservation before traveling. One website that plays an important role in the tourism industry is Traveloka. This study aims to determine the effect of brand image and promotion on the purchase intention of hotel rooms in Badung Regency. The type of sampling used is non-probability sampling with purposive sampling technique with a total sample of 100 respondents. The analysis technique uses validity test, reliability test, classical assumption test, multiple linear regression analysis, hypothesis testing through F test and T test, and coefficient of determination analysis. Traveloka's brand image and promotions have a positive and significant effect on buying interest in hotel rooms in Badung Regency with the results of the calculated F simultaneously being 91.892 > F table = 3.09. Brand image has a positive and significant effect on buying interest in hotel rooms in Badung Regency with a t-count value of 2.565 > t table = 1.661. Traveloka promotions have a positive and significant effect on buying interest in hotel rooms in Badung Regency with the obtained t value of 6.728 > t table = 1.661.
Pengaruh gaya kepemimpinan transformasional dan kepuasan kerja terhadap turnover intention karyawan di golden tulip jineng resort bali
Authors: Prabawa Made Bagus Setya , Wiyasha Ida Bagus Made , Muliadiasa I Ketut 
Published: February 2023

Turnover intention merupakan suatu pemikiran yang dimiliki oleh setiap karyawan untuk berhenti bekerja. Pada Golden Tulip Jineng Resort Bali terdapat permasalahan yaitu tingginya tingkat turnover karyawan. Tujuan penelitian ini adalah untuk mengetahui pengaruh gaya kepemimpinan transformasional dan kepuasan kerja secara parsial turnover intention. Populasi yang digunakan dalam penelitian ini adalah seluruh karyawan non manajerial Golden Tulip Resort Bali sebanyak 64 orang karyawan dengan menggunakan teknik non probability sampling menggunakan sampel jenuh. Pengumpulan data dilakukan dengan metode observasi, wawancara, dan kuisioner. Teknik analisis yang digunakan yaitu menggunakan uji asumsi klasik, analisis regresi linier berganda, koefisien determinasi, uji t, dan uji F. Hasil analisis menunjukan bahwa gaya kepemimpinan transformasional berpengaruh negative dan signifikan terhadap turnover intention karyawan dengan koefisiesn regresi sebesar - 0,233. Kepuasan kerja berpengaruh negatif dan signifikan terhadap turnover intention karyawan dengan koefisiesn regresi sebesar -0,348. Secara stimultan gaya kepemimpinan transformasional dan kepuasan kerja berpengaruh signifikan terhadap turnover intention karyawan. Manajemen Golden Tulip Jineng Resort Bali perlu meningkatkan kenyamanan karyawan dalam bekerja dan kepada pemimpin untuk lebih memperhatikan karyawan sehingga karyawan tidak memiliki keinginan untuk pergi meninggalkan perusahaan.

Turnover intention is a thought possessed by every employee to stop working. The purpose of this study is to determinate the effect of transformational leadership style partially and job satisfaction partialy and simultaneously on turnover intention. The population used in this study were all non- managerial employees of Golden Tulip Jineng Resort Bali, totaling to 64 employees by using non probability sampling and saturate sample.. Data collection is done through observation, interviews, and questionnaires. The analysis technique used is the classical assumption test, multiple linear regression analysis, coefficient of determination analysis, t-test, and f test. The result of analysis shows that transformational leadership style has a negative and significant effect on turnover intention with regression coefficient of -0,233. Job satisfaction has a negative and significant effect on turnover intention with regression coefficient of -0,348. While simultaneously transformational leadership style and job satisfaction significantly influence turnover intention. Golden Tulip Jineng Resort Bali management need to improve employees comfort at work and for the leaders to pay more attention to employees so the employees don’t have the desire to leave the company.
EVALUATION ENERGY SAVINGS AT MALUKU PROVINCE OFFICE BUILDING IN JAKARTA
Authors: Syauta Tommy Martin , Khaerudini Deni Shidqi 
Published: February 2023

The electricity is very important to support activities in office building .The equipment like AC ( Air conditioning ) needs more electricity to be operated. The is almost 60% is use to support this system (AC). This percentage describe that air condition system is an equipment that needs more electricity in the office and its become inefficiency in using electricity. To take overcome for this problem we need to efficiency in using energy. One of the method that now used to efficient that energy is called “ energy conversation” This method is using to saving the energy There is one thing that must be done in this activity which is “ energy audit “. Audit energy is one of method calculate IKE ( Intension Consumption Energy) at on the building.The first preliminary audit shown that more energy, which 60% is use to operated the air conditioning (AC) system and 30% to operate lighting system. IKE for the lighting system is still below from maximum standard which is 15 watt/m²The opportunity of saving energy on audit energy in AC system is done by cleaning up consist of : cleaning up filter, propeller corner fin of the evaporator, and the grill of in door unit.
Service Quality And Brand Awareness Intervention In Affecting Customer Satisfaction At The Bri Bank Pomalaa Unit
Authors: Titing Andry Stepahnie , Sudarnice Sudarnice , Wonua Almansyah Rundu 
Published: February 2023

This study aims to determine the effect of service quality and Brand Awareness toward customer satisfaction of Bank BRI Unit Pomalaa. The type of research used is Explanatory Research with a quantitative approach. The population in this study are the customers of Bank BRI Unit Pomalaa. The data collected using a questionnaire with samples taken as many as 74 respondent. In analyzing the data in this study using SmartPLS. The result of the partial analysis showed that service quality and Brand Awareness has a positive and significant influence on customer satisfaction. Variables of service quality and Brand Awareness has a positive and significant on customer satisfaction of 82,1%
Analysis of Intervening Variables of New Product Performance affected by Tacit Knowledge and Strategic Flexibility
Authors: Hamdani Nizar Alam , Ridwan Muhammad , Maulani Galih Abdul Fatah , Permana Intan 
Published: February 2023

Objectives: Global Innovation Index revealed that the innovation performance of Indonesia is relatively poor compared to several ASEAN countries. The lowest indicator of innovation performance is related to business sophistication. In business activities, some experts identify innovation as the key factor in company competitiveness. The author plans to analyze product innovation, innovation processes, and organizational innovations as intervening variables.Methodology: This study is causal research with a 95% confidence interval in collecting and constructing data structures to evaluate the cause-and-effect relationship of the variables. The primary data was obtained through a survey of 90 small-scale leather apparel companies in Indonesia. Subsequently, the data was analyzed using a structural equation model and multiple.Finding: Compared to the previous studies, the results of this study indicated a novelty, product innovation, and process innovation can be intervening variables if there is strategic flexibility as exogenous variables and new product performance. To improve new product performance, every leather apparel industry in Indonesia must first increase tacit knowledge, strategic flexibility, product innovation, and process innovation.Conclusion: Based on the findings, the researcher suggests further research to examine the path analysis research framework are exogenous variables (strategic flexibility and tacit knowledge), endogenous variables (organizational innovation and new product performance), and intervening variables (product innovation and process innovation).
Effects of hyperbaric oxygen therapy on periodontal disease: a literature review
Authors:   Department of Pediatric Otolaryngology, Head and Neck Surgery, Chairs of Pediatric Surgery, The Independent Public Clinical Hospital No. 6 of the Medical University of Silesia in Katowice John Paul II Upper Silesian Child Health Centre, Katowice, Poland, Latusek Katarzyna , Słotwińska Adrianna ,   Department of Pediatric Otolaryngology, Head and Neck Surgery, Chairs of Pediatric Surgery, The Independent Public Clinical Hospital No. 6 of the Medical University of Silesia in Katowice John Paul II Upper Silesian Child Health Centre, Katowice, Poland, Michniak Anna ,   Dental office for Periodontal and Mucosa Diseases Dental Clinic Zbigniew Zak, Cracow, Poland, Orzechowska-Wylęgała Boguslawa ,   Department of Pediatric Otolaryngology, Head and Neck Surgery, Chairs of Pediatric Surgery, The Independent Public Clinical Hospital No. 6 of the Medical University of Silesia in Katowice John Paul II Upper Silesian Child Health Centre, Katowice, Poland
Published: February 2023

Background and objective: Hyperbaric oxygen (HBO2) has been the subject of research in many areas of dentistry. HBO2 seems to be a useable, additional treatment method. However, there are still no certain conclusions and clear guidelines for procedures. The aim of the study was to collect current literature assessing the use of hyperbaric oxygen therapy in the treatment of periodontitis. Materials and Methods: The following review was performed using medical databases Medline via PubMed and Google Scholar. The review presents articles which assess the effect of hyperbaric oxygen therapy in combination with non-surgical scaling and root planing (SRP) in patients with periodontitis as an adjunctive method to standard protocols. Results: There are potentially plausible mechanisms by which HBO2 could be beneficial. Further welldesigned science research and clinical trials are needed. Due to a small body of literature, differences in methodology and observation periods the data are not sufficient for statistical analysis. Conclusion: The use of HBO2 seems to be reasonable as an adjunct method of the periodontitis treatment. However, authors of this literature review could not unambiguously state that hyperbaric oxygen therapy could be commonly recommended as a potential method of periodontitis treatment. It is essential to develop consistent protocols for the procedure and further research in this area. DOI: 10.22462/01.01.2023.17
UPAYA PERLINDUNGAN ANAK MELALUI PENGEMBANGAN KOMUNITAS PEDULI ANAK DI KABUPATEN SUKABUMI, PROVINSI JAWA BARAT
Authors: Jems Alfro 
Published: February 2023

Abstrak
Perlindungan terhadap anak setiap hari semakin kompleks, hal ini dapat terlihat dengan kekerasan khususnya kekerasan seksual yang terjadi pada anak yang semakin memprihatinkan, oleh karena itu diperlukan sebuah langkah konkrit untuk dapat mencegah terjadinya kekerasan seksual sekaligus mempersiapkan masyarakat untuk dapat memiliki sikap yang tepat dalam menghadapi kekerasan seksual. Terhadap anak. Salah satu pilar yang paling tepat dalam menanggulangi permasalahan ini adalah masyarakat dalam sebuah komunitas, dimana komunitas dapat menjadi wadah yang tepat untuk dapat menyalurkan pengetahuan, nilai dan keterampilan kepada masyarakat agar mampu dalam menganggulangi kekerasan seksual yang terjadi pada anak. Berdasarkan latarbelakang ini maka pertanyaan pada penelitian ini adalah bagaimana membentuk komunitas peduli anak. Sesuai dengan pertanyaan tersebut maka metode penelitian yang dilakukan bersifat kualitatif dengan jenis tindakan. Hasil dari penelitian ini menunjukkan bahwa untuk melakukan upaya perlindungan terhadap anak dapat dilakukan melalui pembentukan sebuah komunitas peduli anak, oleh karena itu diperlukan tahapan berupa memulai, mengorganisasi, membangun profil, membuat rencana dan menerapkan serta mengevaluasi.

Kata kunci: Kekerasan Seksual, Perlindungan Anak, Komunitas.

Abstract
Protection of children is increasingly complex every day, this can be seen by the increasing concern of sexual violence against children, therefore a concrete step is needed to prevent sexual violence from occurring as well as to prepare people to have the right attitude in dealing with sexual violence. Against the child. One of the most appropriate pillars in overcoming this problem is the community in a community, where the community can be the right place to be able to transmit knowledge, values ​​and skills to the community so that they are able to overcome sexual violence against children. Based on this background, the question in this study is how to form a child care community. In accordance with these questions, the research method used is qualitative with the type of action. The results of this study indicate that to make efforts to protect children can be done through the formation of a community caring for children, therefore it takes the stages of starting, organizing, building profiles, making plans and implementing and evaluating.

Keywords: Sexual Violence, Child Protection, Community.