bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of molecular sieve addition on methanol synthesis from CO2 and H2 through alcohol assisted method over CU/ZnO catalyst
Authors:   , Boonamnuay Tanawut 
Published: March 2023

Low-temperature methanol synthesis from CO2 and H2 was carried out using ethanol as catalytic solvent. The alcohol-assisted method reduced synthesis temperature and enhanced methanol yield (35.8%) at 150 oC (5.0 MPa, Cu/ZnO catalyst). However, ethyl acetate and water were generated as byproducts from the reaction. The byproducts formed azeotrope mixture with methanol and led to a complex product purification. Therefore, in this study, molecular sieves (MS) were introduced to adsorb the byproducts. The effect of different MS (3A and 5A) was studied. It was found that MS helped enhancing methanol yield. The highest methanol yield (42.6%) was obtained when adding MS_3A to adsorb water. The MS_5A could separate methanol and ethyl acetate, providing high methanol purity. The effect of operating temperature was also investigated. When reducing temperature, methanol yield decreased but methanol selectivity significantly increased. The optimum temperature was 130 oC where the pleasant methanol yield (30.6%) and selectivity (>98%) were obtained. Controlling temperature and using MS could help enhance the yield and selectivity of methanol.
EVALUATION OF ENDOMETRIAL Bcl-2 EXPRESSION AND Ki-67 PROLIFERATIVE INDEX IN INFERTILE PATIENTS WITH AND WITHOUT POLYCYSTIC OVARY SYNDROME
Authors: KARADEMİR Dilay , USTA Akın , ALTUN Eren 
Published: March 2023

Objective: In women of reproductive age, polycystic ovary syndrome (PCOS) is the most prevalent cause of infertility. The purpose of this study is to compare the Bcl-2 and Ki-67 values between infertile patients with and without PCOS.
Material and methods: The study included twenty-seven infertile patients diagnosed with PCOS and another twenty-eight infertile patients who did not meet the criteria for PCOS. Smoking, pelvic infection symptoms, endometrial polyps and submucosal myomas during a transvaginal ultrasound, pituitary insufficiency, hyperprolactinemia, congenital adrenal hyperplasia, having had adnexal surgery and having a male factor that will result in infertility are all considered exclusion criteria. All patients' data were collected, including age, the length of their infertility, body mass index (BMI), waist-to-hip ratio (WHR), hirsutism score, blood pressure, total testosterone, triglyceride, total cholesterol, LDL, and HDL values, as well as Homa-IR and Hs-CRP readings. The pathology specialist in the examples evaluated Bcl-2 and Ki-67 levels.
Results: We found that BMI, WHR, total testosterone level, blood pressure, total cholesterol, HOMA-IR, and hs-CRP values were significantly higher in infertile cases with PCOS. We also found that the Ki-67 and Bcl-2 values were higher in endometrial cells in sterile PCOS cases than in the control group.
Conclusions: Ki-67 and Bcl-2 levels rise in PCOS patients, preventing apoptosis, limiting the formation of a suitable endometrial environment, and preventing embryo implantation. PCOS patients may frequently experience infertility and recurrent pregnancy losses. The cause of this problem may be the increased activity of estrogen. The primary treatment for PCOS will depend on further investigation into the variables affecting estrogen synthesis and GnRH release. The care plan should be built around this goal.
PROPERTIES OF EARNINGS AND CASH FLOWS IN ALGERIAN COMPANIES
Authors: KIMOUCHE Bilal 
Published: March 2023

This paper aims to analyze the properties of earnings compared to cash flows based on persistence and predictive ability as fundamental attributes of relevance. Therefore, we collected financial data of 20 Algerian companies from 2011 to 2020, where 200 observations were employed using the model of Sloan (1996) that was adjusted by sales. According to the results, the earnings of Algerian companies are highly persistent, but their predictability is weak. However, cash flows are not persistent and have no predictive ability. Consequently, earnings quality in Algerian companies is better than the quality of cash flows. Based on our results, users of financial reports in Algerian companies should focus on earnings when making decisions and be cautious when using cash flows.
Exploring Species Extraction Volume and Residues of Illegal and Conventional Logging Operations
Authors: Boateng Ransford Kwasi , Agyeman Justice Duah , Inyong Stephen , Agbadzah Edmund Senam Kwame , Adjarko Harold 
Published: March 2023

Governments, policymakers, at most public fora, condemn activities of chainsaw operations as illegal and in fact, it has been criminalized with an explanation that it is wasteful and destructive to the environment. The study compared species, diameter distribution, extracted, volume, and residues generated during conventional and illegal logging operations in the forest communities. Using quantitative design approach, the researchers estimated the volume of waste generated by illegal logging and that of conventional loggers and also identified the species targeted. In order to determine the diameter distribution of exploited species, and the recovery rate of logs in both reserves, the researchers measured both ends, diameter, and length of stump wood and merchantable branch wood left as waste using the smallian's formula. The total volume of logs utilized per tree (logvol) was then calculated as the sum of the volume of each log. Twenty-five commercial timber species were identified to have been felled on farmlands compared to 34 commercial species which were felled in the TBFR. On both the farmlands and in the TBFR, the number of species felled by chainsaw operators far exceeded those felled by the conventional loggers. On farmlands, only four (17%) out of the 25 timber species were felled by conventional loggers. The most dominant timber species felled by the conventional loggers on farmlands was ceiba which comprised more than half (53%) of the total trees felled, followed by yaya (32%), watapuo (Cola gigantea), and akasaa (Chrysophyllum albidum). The study concluded that not only do chainsaw operators target a variety of lumber species but they also exploit timber species that are near extinction, therefore, making their activities pose danger to species diversity and conservation. The study proposed that strengthening the policy regime on compensation payment could help reduce the Incidence of illegal logging.
Pathogenicity of Aspergillus fumigatus in Experimental Infection of Different Developmental Stages of Clarias gariepinus
Authors: Owolabi Margaret Omotayo , Anifowose Olayinka Remilekun , Oladosu Gbolahanmi Akinola , Owolabi Oluwaseyi Oyeniyi 
Published: March 2023

Aims: This study aimed to investigating the pathogenicity of Aspergillus fumigatus in the experimental infection of Clarias gariepinus fingerlings and juvenile catfish.
Experimental Procedure: Aspergillus fumigatus used for this study was isolated from the gills and liver of infected juveniles presented for microbial diagnostic examination, cultured on Sabouraud dextrose agar for 3 – 4 days, and identified at the Aquatic Animal and Wildlife Laboratory (AAWL), Department of Veterinary Medicine, University of Ibadan.
Methodology: One hundred and forty healthy eight-week old Clarias gariepinus fingerlings (average weight of 4g) and 140 healthy sixteen-week old juvenile (average weight of 10g) were purchased from a commercial fish farms in Ibadan. The fingerlings and juveniles were randomly divided into seven groups, each with 20 fish in five litters of water. The fungal suspension containing 3.2 X 106 spores/ml of Aspergillus fumigatus was used for the pathogenicity test. Six groups were infected by immersion in water containing fungal spores at the rates of 2ml/L and 5ml/L for fingerlings and juveniles respectively. The clinical signs, skin lesions and mortality were observed daily for 14 days.
Results: Aspergillus fumigatus isolated in this study has green spiked conidia; and the size of the conidia is 2.5µm. The conidia have a smooth surface and small spikes covering their surface. Moreover, the mortality rate was significantly (p = 0.40) higher in infected fingerlings (80%) than juveniles (62%) at fourteen days post-infection. The gross lesions observed during experimental infection of fingerlings and juveniles included exophthalmia, atrophied barbel, congested trunk kidney, hyperemia of gill filaments, and skin depigmentation. The histopathological organ changes caused by Aspergillus fumigatus were obvious in the liver and gills. Vacuolar degeneration of hepatocytes and necrosis of some melanomacrophage cells, in addition, severe erosion of the primary and secondary lamellae, were observed in infected juveniles.
Conclusion: Aspergillus fumigatus causes high mortality in fingerlings and juvenile of African Catfish (Clarias gariepinus).
Association of Nonconcussive Repetitive Head Impacts and Intense Physical Activity With Levels of Phosphorylated Tau181 and Total Tau in Plasma of Young Elite Soccer Players
Authors: Cente Martin , Perackova Janka , Peracek Pavol , Majdan Marek , Toth Igor , Mikulic Martin , Hanes Jozef , Porubska Sara , Spajdel Marian , Kazickova Barbora , Jurisica Igor , Filipcik Peter 
Published: March 2023

ImportanceHead impacts resulting in traumatic brain injury (TBI) lead to the elevation of phosphorylated tau protein (p-tau181) in plasma. To our knowledge, this study is the first to investigate dynamics of p-tau181 levels and the ratio of p-tau181 to total tau in individuals after nonconcussive head impacts.ObjectiveTo determine the association of repetitive low-intensity head impacts on p-tau181 and total tau protein levels in the plasma of young adult elite soccer players and assess the possible association of head impacts with focused attention and cognitive flexibility.Design, Setting, and ParticipantsIn this cohort study, young elite soccer players performed intense physical activity with and without heading the ball. The study was conducted at a university facility in Slovakia from October 1, 2021, to May 31, 2022. Eligible participants were selected based on similarities in demographic variables, excluding those with a history of TBI.Main Outcomes and MeasuresThe primary study outcomes were the levels of total tau protein and p-tau181 in plasma samples and the cognitive status of the study participants.ResultsA total of 37 male athletes participated in the study (mean [SD] age: exercise group, 21.6 [1.6] years; heading group, 21.2 [1.5] years). We found significantly elevated levels of total tau and p-tau181 in the plasma of soccer players 1 hour after physical exercise (tau, 1.4-fold; 95% CI, 1.2-1.5; P &amp;lt; .001; p-tau181, 1.4-fold; 95% CI, 1.3-1.5, P &amp;lt; .001) and repetitive head impacts (tau, 1.3-fold; 95% CI, 1.2-1.4; P &amp;lt; .001; p-tau181, 1.5-fold; 95% CI, 1.4-1.7 P &amp;lt; .001). The ratio of p-tau181 to tau was significantly higher 1 hour after exercise and heading training, and remained elevated specifically in the heading group even after 24 hours (1.2-fold; 95% CI, 1.1-1.3; P = .002). Performance in cognitive tests revealed a significant decline in focused attention and cognitive flexibility after physical exercise and heading training; physical exercise of higher intensity without heading training was associated with a greater negative cognitive performance than heading only.Conclusions and RelevanceIn this cohort study of young elite soccer players, the elevation of p-tau181 and tau was observed after acute intense physical activity and nonconcussive repetitive head impacts. The increase of p-tau181 levels relative to tau after 24 hours indicated an acute enrichment of phosphorylated tau fraction in the periphery when compared with preimpact levels; an imbalance of tau proteins may have long-lasting consequences in the brain of head-impacted individuals.
2D Materials‐Based Electrochemical Triboelectric Nanogenerators
Authors: Pace Giuseppina , del Rio Castillo Antonio Esau , Lamperti Alessio , Lauciello Simone , Bonaccorso Francesco 
Published: March 2023

AbstractThe integration of 2D materials in triboelectric nanogenerators (TENGs) is known to increase the mechanical‐to‐electrical power conversion efficiency. 2D materials are used in TENGs with multiple roles as triboelectric material, charge‐trapping fillers, or as electrodes. Here, novel TENGs based on few‐layers graphene (FLG) electrodes and stable gel electrolytes composed of liquid phase exfoliated 2D‐transition metal dichalcogenides and polyvinyl alcohol are developed. TENGs embedding FLG and gel composites show competitive open‐circuit voltage (≈ 300 V), instant peak power (530 mW m−2), and stability (> 11 months). These values correspond to a seven‐fold higher electrical output compared to TENGs embedding bare FLG electrodes. It is demonstrated that such a significant improvement depends on the high electrical double‐layer capacitance (EDLC) of FLG electrodes functionalized with the gel composites. The wet encapsulation of the TENGs is shown to be an effective strategy to increase their power output further highlighting the EDLC role. It is also shown that the EDLC is dependent upon the transition metal (W vs Mo) rather than the relative abundance of 1T or 2H phases. Overall, this work lays down the roots for novel sustainable electrochemical‐(e)‐TENGs developed exploiting strategies typically used in electrochemical capacitors.
Insights into the Pseudocapacitive Behavior of Sulfurized Polymer Electrodes for Li–S Batteries
Authors: Sapkota Nawraj , Chiluwal Shailendra , Parajuli Prakash , Rowland Alan , Podila Ramakrishna 
Published: March 2023

AbstractPractical applications of sulfurized polymer (SP) materials in Li–S batteries (LSBs) are often written off due to their low S content (≈35 wt%). Unlike conventional S8/C composite cathodes, SP materials are shown to function as pseudocapacitors with an active carbon backbone using a comprehensive array of tools including in situ Raman and electrochemical impedance spectroscopy. Critical metric analysis of LSBs containing SP materials with an active carbon skeleton shows that SP cathodes with 35 wt% S are suitable for 350 Wh kg−1 target at the cell level if S loading >5 mg cm−2, electrolyte‐to‐sulfur ratio <2 µL mg−1, and negative‐to‐positive ratio <5 can be achieved. Although 3D current collectors can enable such high loadings, they often add excess mass decreasing the total capacity. An “active” carbon nanotube bucky sandwich current collector developed here offsets its excess weight by contributing to the electric double layer capacity. SP cathodes (35 wt% S) with ≈5.5 mg cm−2 of S loading (≈15.8 mg cm−2 of SP loading) yield a sulfur‐level gravimetric capacity ≈1360 mAh gs−1 (≈690 mAh gs−1), electrode level capacity 200 mAh gelectrode−1 (100 mAh gelectrode−1), and areal capacity ≈7.8 mAh cm−2 (≈4.0 mAh cm−2) at 0.1C (1C) rate for ≈100 cycles at E/S ratio = 7 µL mg−1.
Optimally Configured Optical Fiber Near‐Field Enhanced Plasmonic Resonance Immunoprobe for the Detection of Alpha‐Fetoprotein
Authors: Jing Jianying , Liu Kun , Jiang Junfeng , Xu Tianhua , Xiao Lu , Zhan Xiaohan , Liu Tiegen 
Published: March 2023

AbstractThe detection of trace biomarkers is an important supplementary approach for early screening and diagnoses of tumors. An optical fiber near‐field enhanced plasmonic resonance immunoprobe is developed for the detection of the hepatocellular carcinoma biomarker, i.e., the alpha‐fetoprotein. Generic principles based on dispersion models and finite element analysis (FEA) models are developed to realize the optimized configuration of spectral characteristics of the immunoprobe. Dispersion models provide theoretical guidance for the design of the multilayer sensing structure from the perspective of the ray optics theory. FEA models provide theoretical guidance for the selection of coating materials from the perspective of the self‐defined dielectric constant ratio, i.e., the ratio of the real part to the imaginary part. The optimized configuration of the antibody coupling further improves the biosensing performance of the immunoprobe. The limit of detection (LOD) can reach down to 0.01 ng mL−1, which is one order of magnitude lower than those relevant reported works. Such a low LOD can more effectively avoid the accuracy degradation of detection results due to measurement errors. Human serum samples have also been detected, with the good precision achieved. This work shows promising prospects in applications of label‐free, low‐cost, rapid, and convenient early screening of tumors.
Nanographene‐Based Heterojunctions for High‐Performance Organic Phototransistor Memory Devices
Authors: Bai Shaoling , Yang Lin , Haase Katherina , Wolansky Jakob , Zhang Zongbao , Tseng Hsin , Talnack Felix , Kress Joshua , Andrade Jonathan Perez , Benduhn Johannes , Ma Ji , Feng Xinliang , Hambsch Mike , Mannsfeld Stefan C. B. 
Published: March 2023

AbstractOrganic phototransistors can enable many important applications such as nonvolatile memory, artificial synapses, and photodetectors in next‐generation optical communication and wearable electronics. However, it is still a challenge to achieve a big memory window (threshold voltage response ∆Vth) for phototransistors. Here, a nanographene‐based heterojunction phototransistor memory with large ∆Vth responses is reported. Exposure to low intensity light (25.7 µW cm−2) for 1 s yields a memory window of 35 V, and the threshold voltage shift is found to be larger than 140 V under continuous light illumination. The device exhibits both good photosensitivity (3.6 × 105) and memory properties including long retention time (>1.5 × 105 s), large hysteresis (45.35 V), and high endurance for voltage‐erasing and light‐programming. These findings demonstrate the high application potential of nanographenes in the field of optoelectronics. In addition, the working principle of these hybrid nanographene‐organic structured heterojunction phototransistor memory devices is described which provides new insight into the design of high‐performance organic phototransistor devices.
Traffic Lights for Catalysis: Stimuli‐Responsive Molecular and Extended Catalytic Systems
Authors: Thaggard Grace C. , Haimerl Johanna , Fischer Roland A. , Park Kyoung Chul , Shustova Natalia B. 
Published: March 2023

AbstractThe advances made in the field of stimuli‐responsive catalysis during the last five years with a focus on the novel recently‐emerged directions and applications have been surveyed. Metal‐free catalysts and organometallic complexes, as well as biomimetic systems and extended structures, which display switchable catalytic activity for a variety of organic transformations, are discussed. Light‐activated systems comprised of photochromic molecules capable of modulating reaction rate, yield, or enantioselectivity based on geometric and electronic changes associated with photoisomerization are the focus of the detailed discussion. Alternative stimuli, including pH and temperature, which could be applied either alone or in combination with light, are also addressed. Recent advances clearly demonstrate that the capability to finely tune catalyst behavior via an external stimulus is a powerful tool that could alter the landscape of sustainable chemistry.
Recent advances in mesenchymal stem/stromal cells (MSCs)‐based approaches for osteoarthritis (OA) therapy
Authors: Hassanzadeh Ali , Vousooghi Nasim , Rahimnia Ramin , Razeghian Ehsan , Rajaeian Simin , Seyhoun Iman , Sharif Shiva , Verdi Javad 
Published: March 2023

AbstractRecently, mesenchymal stem/stromal cells (MSCs) transplantation has been introduced as a promising option to support cartilage structure and improve its function in preclinical models and patients suffering from osteoarthritis (OA). MSCs strongly provoke their preferred influence in vivo by inhibiting the inflammatory responses and applying immunomodulation by releasing anti‐inflammatory mediators such as transforming growth factor‐β and interleukin‐10. Such mediators downregulate fibroblast‐like synoviocytes growth and migration, leading to chondroprotection. Furthermore, improving the chondrocyte proliferation and extracellular matrix hemostasis in addition to the suppression of the matrix metalloproteinases activities can support cartilage tissue organization. In this light, various published results have demonstrated that MSCs therapy can considerably decrease pain and restore knee function in OA patients. In the current review, we have concentrated on recent advances in MSCs‐based therapeutics to elicit both chondrogenic and chondroprotective impacts in OA patients, focusing on the last decade in vivo results.
Measures of social deprivation and outcomes after percutaneous coronary intervention
Authors: Torabi Asad J. , Von der Lohe Elisabeth , Kovacs Richard J. , Frick Kyle A. , Kreutz Rolf P. 
Published: March 2023

AbstractBackgroundDisparities in socioeconomic status are a frequently cited factor associated with worse cardiovascular outcomes. The social deprivation index (SDI) can be used to quantify socioeconomic resources at the population level.ObjectivesThe aim of this study was to assess the association of SDI with clinical outcomes following percutaneous coronary interventions (PCI).MethodsThis was a retrospective observational analysis of patients who underwent PCI and were included in a multicenter cardiac catheterization registry study. Baseline characteristics, congestive heart failure (CHF) readmission rates and survival were compared between patients with the highest and lower SDI. SDI was calculated based on the US community survey census tract‐level data.ResultsPatients within the highest SDI quintile (n = 1843) had more comorbidities and a higher risk of death [hazard ratio (HR): 1.22 (95% confidence interval, CI: 1.1–1.39, p = 0.004); log rank: p = 0.009] and CHF readmission [HR: 1.56 (1.39–1.75, p < 0.001); log rank: p < 0.001) as compared with those in the lower quintiles (n = 10,201) during mean follow‐up of 3 years. Increased risk of highest SDI for all‐cause mortality and CHF remained significant after adjustment in multivariable analysis for factors associated with highest SDI.ConclusionsPatients within the highest SDI quintile had a greater proportion of comorbidities as well as higher risk for adverse outcomes as compared with patients with a lower SDI following PCI.
Professional identity development of international counseling doctoral students: A hybrid approach of deductive and inductive thematic analysis
Authors: Li Dan , Liu Yanhong 
Published: March 2023

AbstractWe explored the professional identity development of nine international counseling doctoral students. Our findings broadly corroborated Dollarhide et al.’s general model but revealed further nuances that need to be carefully contextualized at the intersection of a constellation of identities and experiences that international students bring to the counseling profession.
Magnetic Peroxidase Nanozyme Gears Up for Microplastic Removal and Deconstruction
Authors: Palliyarayil Ansari , Kumar Borah Rajani , Vernekar Amit A. 
Published: March 2023

AbstractPlastic is an important commodity that is used in several sectors. However, plastic waste generation is a pressing issue and needs attention as it risks the environment. While methods such as landfilling, incineration and recycling are known for handling plastic waste, they have their own limitations like generation of secondary pollutants and the low quality of the recycled plastic. In this scenario, new methods and technologies for efficiently handling plastic waste are the need of the hour as it is aggravating the concern of pollution and its health risks. This highlight article predominantly focuses on the recently reported combinatorial approach (Angew. Chem. Int. Ed. 2022, 61, e202212013), where it has been shown that integrating the magnetic property of bare Fe3O4 nanoparticles and nanozyme technology can be used for microplastic removal and degradation with nearly 100 % efficiency.