bluuebunny/crossref_metadata_2025_split huggingface dataset:
A comparative study of the two leadless pacemakers in clinical practice
Authors: Shantha Ghanshyam , Brock Jonathan , Singleton Matthew J. , Schmitt Alexander Joseph , Kozak Patrick , Bodziock George , Bradford Natalie , Whalen Patrick , Bhave Prashant 
Published: July 2023

AbstractIntroductionAVEIR‐VR leadless pacemaker (LP) was recently approved for clinical use. Although trial data were promising, post‐approval real world data with regard to its effectiveness and safety is lacking. To report our early experience with AVEIR‐VR LP with regard to its effectiveness and safety and compare it with MICRA‐VR.MethodsThe first 25 patients to undergo AVEIR‐VR implant at our institution between June and November 2022, were compared to 25 age‐ and sex‐matched patients who received MICRA‐VR implants.ResultsIn both groups, mean age was 73 years and 48% were women. LP implant was successful in 100% of patients in both groups. Single attempt deployment was achieved in 80% of AVEIR‐VR and 60% of MICRA‐VR recipients (p = 0.07). Fluoroscopy, implant, and procedure times were numerically longer in the AVEIR‐VR group compared to MICRA‐VR group (p > 0.05). No significant periprocedural complications were noted in both groups. Incidence of ventricular arrhythmias were higher in the AVEIR‐VR group (20%) compared to the MICRA‐VR group (0%) (p = 0.043). At 2 and 8 weeks follow‐up, device parameters remained stable in both groups with no device dislodgements. The estimated battery life at 8 weeks was significantly longer in the AVEIR‐VR group (15 years) compared to the MICRA‐VR group (8 years) (p = 0.047). With 3−4 AVEIR‐VR implants, the learning curve for successful implantation reached a steady state.ConclusionOur initial experience with AVEIR‐VR show that it has comparable effectiveness and safety to MICRA‐VR. Larger sample studies are needed to confirm our findings.
Genotypic and phenotypic analysis ofElizabethkingia meningosepticain bullfrogRana catesbeianaisolated in Taiwan
Authors: Tsai Ming‐An , See Ming She , Chiu Cheng‐Hsun , Wang Pei‐Chi , Chen Shih‐Chu 
Published: July 2023

AbstractElizabethkingia meningosepticais a hazardous bacterium for agriculture production and human health. The present study identifiedE. meningosepticafrom the bullfrog, human and reference strain BCRC 10677 by API 20NE, 50S ribosome protein L27 sequencing and pulse field gel electrophoresis to differentiate isolates ofE. meningosepticafrom aquatic animals and humans. All isolates from bullfrogs and humans were identified asE. meningosepticaby DNA sequencing with 98.8%–100% sequence identity.E. meningosepticadisplayed significant genetic diversity when analysed using pulsed‐field gel electrophoresis (PFGE). There were six distinct pulsotypes, including one pulsotype found in bullfrog isolates and five pulsotypes found in human isolates. However,E. meningosepticafrom bullfrog exhibited one genotype only by PFGE. Overall, molecular epidemiological analysis of PFGE results indicated that the frogE. meningosepticaoutbreaks in Taiwan were produced by genetically identical clones. The bullfrog isolates were not genetically related to otherE. meningosepticafrom human and reference isolates. This research provided the first comparisons of biochemical characteristics and genetic differences ofE. meningosepticafrom human and bullfrog isolates.
Establishing a time‐varying flood‐wave impulse function combined with a dynamic machine‐learning technique in response to the disturbance of boundary conditions
Authors: Huang Pin‐Chun 
Published: July 2023

AbstractTo seek other alternative approaches besides numerical methods, the linearized Saint Venant equations were utilized to derive the channel response functions for simulating streamflow. This study advocates developing a new approach to make the temporal distribution of response functions more flexible by introducing time‐varying reference parameters which depend on both the upstream inflow and the downstream boundary conditions. Moreover, to expand the model applicability in natural channels with irregular cross‐sectional shapes affected by the unsteady inflow, lateral flow, and the variation of tide level, a dynamic neural network algorithm is jointly applied to determine more appropriate time‐varying hydraulic parameters which are adopted in the channel flow response functions respectively derived from upstream and downstream boundary conditions. The tidal level at the estuary and the upstream inflow discharge are simultaneously considered influential factors to determine an optimal set of reference parameters by applying a machine learning technique, and this prediction can further be provided for updating the channel response functions. The novelty of this study is to propose a complete methodology to combine channel response functions with the machine learning algorithm for ameliorating the accuracy of channel flow simulation and resolving the uncertainty of model parameters. Therefore, by using the proposed method, not only the physical mechanism of Saint Venant equations can be preserved, but also the optimal hydraulic parameters can be specified. The problem of numerical instability during channel flow routing can be eliminated by using the proposed new model and therefore the reliability of real‐time flood forecasting can be reinforced.
The Effects of the Jump‐In Whole‐School Intervention on the Weight Development of Children in Amsterdam, the Netherlands
Authors: Busch Vincent , Steenkamer Ilona , van Nassau Femke , van Opdorp Paul , van Houtum Lieke , Verhoeff Arnoud , Twisk Jos 
Published: July 2023

ABSTRACTBACKGROUNDThis study assessed the effects of the “Jump‐in” whole‐school intervention in Amsterdam, the Netherlands, on children's weight development by comparing children exposed to the intervention and controls from 3 other large Dutch cities. Jump‐in is a comprehensive intervention that aims to stimulate healthy nutrition and physical activity in children at primary schools in Amsterdam. In addition, the relationship between the intervention's implementation degree and its effectiveness was studied.METHODSDemographic and anthropometric data, collected by youth health care professionals via routine health checks at T0 (2014) and T1 (2019), were used to analyze possible intervention effects by comparing the weight development of children exposed to the Jump‐in intervention versus unexposed controls. Implementation logs from health promotion professionals were used to determine intervention effects per implementation degree. Multilevel regression analyses were used for all analyses.RESULTSIn total, 4299 children were included mean age ± 5.5 years (T0), 10.6 years (T1), and ≈50% boys/girls at both times. Receiving the fully implemented intervention resulted in a decline in standardized body‐mass index (zBMI) compared to the controls (−0.23, confidence interval [CI] −0.33, −0.13). It also led to higher odds to move into a healthier weight category over time (odds ratio [OR] 1.36, CI 1.06, 1.74), yet no statistically significant shift towards a healthy weight was found.CONCLUSIONSRelative to the controls, children exposed to the intervention showed positive zBMI developments, with stronger effects when the implementation degree was higher. Despite positive results, creating more impact might require the further integration of school‐based programs into whole‐systems approaches that include other energy‐balance behaviors.
Cigarette smoke exposure of hospitalised children: Prevalence of smoking in parents or carers and admission practices of health services
Authors: Slattery Breanna , Dimond Renee , Went Grace , Ugalde Anna , Wong Shee Anna 
Published: July 2023

AimThe aim of this study is to understand the exposure to second‐hand tobacco smoke in the homes of hospitalised children through: (i) understanding the prevalence of smoking in adults or carers and (ii) examining the health services' approach to identifying parental smoking status.MethodsThis prospective observational study consisted of two surveys: one administered to parents/carers of hospitalised children and one to health services. The first cross‐sectional survey aimed to elicit the proportion of children requiring admission to a regional Victorian general paediatric unit who live with adults who smoke cigarettes. The survey was delivered to participating parents/carers during the standard nursing admission process. The second survey was administered across 15 public health services to determine if identification of parent/carer's smoking status is a routine part of their standard paediatric admission practice.ResultsFor the parental survey, 453 responses were obtained from 782 consecutive new admissions. Nearly a third (n = 136, 30%) requiring hospital admission were found to be living with at least one parent/carer who identified as a current cigarette smoker. Of the 15 health services surveyed, only four (27%) nursing units reported routinely asking parents/carers about their smoking status as part of their standard admission process.ConclusionAdmission to hospital provides an opportunity to enhance care for children by addressing nicotine dependence within their families. Findings suggest routine recording of smoking status can be improved, to drive smoking cessation and brief intervention conversations with parents and carers of children admitted to hospital.
Parasympathetic Nervous System Activity During Measures of Volitional Self‐regulation Predicts School Readiness
Authors: Holochwost Steven J. , Coffman Jennifer L. , Wagner Nicholas J. , Gomes Lindsay A. , Propper Cathi B. 
Published: July 2023

ABSTRACTSelf‐regulation is an essential component of school readiness. Although in educational contexts self‐regulation is typically defined in terms of volitional processes, it also encompasses the activity of neurophysiological systems, including the parasympathetic nervous system (PNS). In a prospective longitudinal study, 102 preschoolers (Mage = 4.82 years; 52% female) completed two measures of volitional self‐regulation (the gift‐wrap task and a battery of EF tasks) at the beginning of their final preschool year, and then completed the Bracken School Readiness Assessment (BSRA) at year's end. Larger increases in parasympathetic function (indexed by respiratory sinus arrythmia, or RSA) during both the gift‐wrap and EF tasks were correlated with better performance on the BSRA at levels approaching significance, and subsequent regression models that controlled for relevant covariates revealed robust associations between increases in RSA and improved BSRA performance (gift wrap: B = 5.49, p = .012; EF: B = 7.77, p = .001). We interpret these results in light of polyvagal theory and discuss their implications for incorporating measures of parasympathetic activity into future educational neuroscience research.
Addendum: Central‐Auckland rainfall, 1853–2020—Sites histories and implications for developing a long‐term rainfall record
Authors: Fowler Anthony M. 
Published: July 2023

AbstractFowler (2021a, New Zealand Geographer, 77, 16–31) supplemented the site histories of four central‐Auckland climate observatories by mining two searchable online historical archives (Papers Past, DigitalNZ). Photographic and map evidence was found for three of the sites, but not for the Auckland Domain observatory. Additional information (a map) has now been found which allows a more accurate determination of that site's location. The new information is presented here and the implications for the central‐Auckland rainfall record are noted.
Does Immediate Postoperative Early Ambulation Affect Clinical Results of Full‐Endoscopic Lumbar Discectomy? A Historical Control Study of Daytime Operation with a 8‐Hour Hospital Stay versus Inpatient Operation
Authors: Yu Lingjia , Zhu Bin , Dong Huajun , Li Xiang , Liu Xiaoguang , Yang Yong , Yi Zuling 
Published: July 2023

ObjectiveFull‐endoscopic lumbar discectomy (FELD) is a popular operation for the treatment of lumbar disc herniation (LDH) and day surgery mode is increasingly popular. However, only a few studies have reported about day surgery patients undergoing Percutaneous endoscopic lumbar discectomy (PELD). This retrospective study was to evaluate and analyze the clinical outcomes of patients undergoing FELD for LDH as day surgery versus inpatient surgery.MethodsFrom January 2020 to January 2022, a retrospective analysis of LDH patients treated with FELD either in day surgery unit (within 8‐h hospital stay) or inpatient unit was carried out. All these patients were followed‐up for at least 12 months, and were categorized into a FELD‐I (inpatient surgery) group or a FELD‐D (day surgery) group, according to where the surgical procedures were performed. We assessed and compared the postoperative stand and walk time, postoperative hospitalization stays, time of return to work, modified MacNab criteria, willingness to recommend surgery, complications, revision rate, as well as the visual analogue scale (VAS) and the Oswestry disability index score (ODI). Student t‐test was used for continuous variables and chi‐square test or Fisher's exact test was used for categorical variables.ResultsThere was no statistically significant difference in demographic data and baseline characteristics between two groups. And no significant differences were found in MacNab criteria between two groups. Postoperative VAS and ODI scores at one‐day postoperation and final follow‐up both improved significantly in both groups, as compared to the preoperative data (p < 0.001). However, no significant difference was found between the two groups on the pre, postoperative, or the last follow‐up score for VAS and ODI (p > 0.05). The postoperative first ambulation time and postoperative hospital stays was much longer in FELD‐I group than FELD‐D group (p < 0.001). However, there were no significant differences in the perioperative complications, revision rate as well as satisfaction rate between two groups (p > 0.05). The overall time of return to work of young patients (<60 years‐old) in the FELD‐D group was significantly shorter than that in the FELD‐I group (p = 0.001). Patients in the FELD‐D group were more likely to recommend this kind of surgical model.ConclusionThese data suggest that FELD‐D can be effectively performed as day surgery (within 8 h hospital stay). Early ambulation after FELD‐D did not affect the clinical outcomes and the revision rates. Day surgery patients are more likely to recommend this surgery mode to other patients and younger patients may be able to return to work earlier.
Arthroscopy Confers Favorable Clinical Outcomes in Asian Patients with Borderline Developmental Dysplasia of the Hip
Authors: Yang Fan , Zhou Zheng , Zhang Xin , Huang Hongjie , Ju Xiaodong , Wang Jianquan 
Published: July 2023

ObjectiveHip arthroscopy has recently appeared as a successful therapy in treating borderline developmental dysplasia of the hip (BDDH). This study aimed to describe the minimal 2‐year follow‐up after hip arthroscopy for patients with BDDH in the Asian population and use the combination of lateral center edge angle (LCEA) and alpha angles to detect the appearance of impingement in the BDDH population.MethodsThis retrospective investigation was conducted utilizing information from arthroscopically treated BDDH patients in 2018 and 2019. The following patient‐reported outcomes were reported: modified Harris Hip Score, Hip Outcome Score‐Activities of Daily Living, International Hip Outcome Tool 12‐component form, and Visual Analog Scale. We also considered the clinical data regarding radiological measurements, intraoperative findings, interventions, complications, and subsequent surgical revisions, in the analysis of combination angles in detecting the occurrence of impingement. Patients with asymptomatic contralateral hips from traumatic hip injury (pelvic fracture) served as the control group. A 2:1 propensity score matching was based on age, sex, and BMI. A receiver operating characteristic curve (ROC) was used to identify the thresholds of combination angles and their accuracies.ResultsA total of 77 hips met the inclusion and exclusion requirements. After the follow‐up period, most patients showed a considerable improvement in patient‐reported outcomes compared to their preoperative values (P < 0.001 for all). The overall rate of complications was 5.2%, whereas the rate of revisions was 3.9%. Increasing preoperative alpha angle age was significantly positively correlated with improving patient‐reported outcomes. The combined angle cut‐off was determined to be 80.5° (AUC, 0.858; 95% CI: 0.757–0.938; sensitivity (SE), 98.1%; specificity (SP), 74.1%; P < 0.001) for the occurrence of impingement in BDDH population.ConclusionGood patient‐reported outcomes and low revision rates can be expected in the BDDH population with careful selection of patients in Asian populations. A combination angle >80.5° could be a reliable predictive factor of impingement in BDDH populations.
Plantar keratoderma‐like crusted scabies in an immunocompetent infant after topical steroids
Authors: Segado Sánchez Marta , Lova Navarro Miguel , Martínez Ortega Francisco José , Parra García José Juan , López Martínez Diego , Sánchez‐Pedreño Guillén Paloma 
Published: July 2023

AbstractA healthy 6‐month‐old girl presented with plantar keratoderma‐like lesions unresponsive to topical corticosteroids. Nocturnal pruritus in 13 relatives, presence of burrows on clinical exam, and the positive scabies preparation led to the diagnosis of crusted scabies. She was successfully treated with topical and oral scabicides. Crusted scabies is a severe form of Sarcoptes scabiei infection uncommon in immunocompetent subjects, in whom previous corticosteroid use may favor its occurrence.
Increased incidence of mitral valve prolapse in children with pectus chest wall deformity
Authors: Karabulut Muhammed 
Published: July 2023

AbstractBackgroundPectus anomalies constitute 95% of chest anomalies. Pectus carinatum (PC) and excavatum (PE) are often asymptomatic in childhood. However, symptoms and signs such as chest pain, dyspnea, and mitral valve prolapse (MVP) can be seen in pectus anomalies. Demographic characteristics and accompanying cardiac signs in children with pectus deformity were investigated.MethodsIn this study, the clinical findings for children with pectus deformity, and the incidence of MVP and other concomitant heart diseases detected in echocardiographic examinations were evaluated.ResultsEighty‐two children with PE, 27 with PC, and 107 healthy children were included in this study. In the echocardiographic examination of PE, PC patients, and healthy children, MVP was detected with frequencies of 25%, 33%, and 2% respectively.ConclusionsThe study showed that pectus anomalies were associated with an increased incidence of MVP. All patients with pectus deformity should therefore undergo a screening echocardiogram in adolescence to assess for the presence of MVP.
ABA spray on Arabidopsis seedlings increases mature plants vigor under optimal and water‐deficit conditions partly by enhancing nitrogen assimilation
Authors: Khoshniat Parisa , Rafudeen Muhammad Suhail , Seifi Alireza 
Published: July 2023

AbstractHere, we report the effects of a single abscisic acid (ABA) spray on Arabidopsis seedlings on growth, development, primary metabolism, and response to water‐deficit stress in adult and next‐generation plants. The experiments were performed over 2 years in two different laboratories in Iran and South Africa. In each experiment, fifty 7‐day‐old Arabidopsis seedlings were sprayed with 10 μM ABA, 1 mM H2O2, distilled water, or left without spraying as priming treatments. Water‐deficit stress was applied on half of the plants in each treatment by withholding water 2 days after spraying. Results showed that a single ABA spray at the cotyledonary stage significantly increased plant biomass and delayed flowering. The ABA spray significantly enhanced drought tolerance so that the survival rate after rehydration was 100 and 33% in the first and the second experiments, respectively, for ABA‐treated plants compared to 35 and 0% for water‐sprayed plants. This enhanced drought tolerance was not inheritable. Metabolomics analyses suggested that ABA probably increases the antioxidant capacity of the plant cells and modulates tricarboxylic acid cycle toward enhanced nitrogen assimilation. Strikingly, we also observed that the early water spray decreases mature plant resilience under water‐deficit conditions and cause substantial transient metabolomics perturbations.
Permaculture and back‐to‐the‐land migration: Pursuing self‐sufficiency in Czech rural areas
Authors: Kolářová Marta 
Published: July 2023

AbstractThis article focuses on the contemporary back‐to‐the‐land migration of permaculture practitioners in post‐socialist (1989–) Czechia. It explores the ideals and practices of self‐sufficiency among back‐to‐the‐land migrants as they relate to their migration motives and post‐migration life, including the fulfilment of a dream of self‐sufficiency and local community integration. This article deals with individual in‐rural migrant projects and the experiences of permaculturists who live in intentional eco‐communities. It draws upon data from in‐depth interviews with back‐to‐the‐land migrants and analysis of documents and field notes. The article concludes that the self‐sufficient vision, part of a ‘family homestead’ concept promoted by permaculture teachers, is difficult to achieve for rural newcomers who must reformulate their visions to match the lived reality. The post‐migration life of this group is further complicated by disillusionment with local community relations and difficulties integrating within their migration destination because of their distinctive lifestyle. Czech back‐to‐the‐land migration related to permaculture differs from its western version in its inclination towards nature‐based spirituality and a specific land structure still influenced by the forced collectivisation of the communist era.
The interplay of post‐translational protein modifications in Arabidopsis leaves during photosynthesis induction
Authors: Giese Jonas , Eirich Jürgen , Walther Dirk , Zhang Youjun , Lassowskat Ines , Fernie Alisdair R. , Elsässer Marlene , Maurino Veronica G. , Schwarzländer Markus , Finkemeier Iris 
Published: July 2023

SUMMARYDiurnal dark to light transition causes profound physiological changes in plant metabolism. These changes require distinct modes of regulation as a unique feature of photosynthetic lifestyle. The activities of several key metabolic enzymes are regulated by light‐dependent post‐translational modifications (PTM) and have been studied at depth at the level of individual proteins. In contrast, a global picture of the light‐dependent PTMome dynamics is lacking, leaving the response of a large proportion of cellular function undefined. Here, we investigated the light‐dependent metabolome and proteome changes in Arabidopsis rosettes in a time resolved manner to dissect their kinetic interplay, focusing on phosphorylation, lysine acetylation, and cysteine‐based redox switches. Of over 24 000 PTM sites that were detected, more than 1700 were changed during the transition from dark to light. While the first changes, as measured 5 min after onset of illumination, occurred mainly in the chloroplasts, PTM changes at proteins in other compartments coincided with the full activation of the Calvin–Benson cycle and the synthesis of sugars at later timepoints. Our data reveal connections between metabolism and PTM‐based regulation throughout the cell. The comprehensive multiome profiling analysis provides unique insight into the extent by which photosynthesis reprograms global cell function and adds a powerful resource for the dissection of diverse cellular processes in the context of photosynthetic function.