bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effectiveness of online advanced C.A.R.E suicide prevention gatekeeper training program among healthcare lecturers and workers in national university of Malaysia: A pilot study
Authors: Roslan Amran Fadzrul , Pheh Kai Shuen , Mahadevan Raynuha , Bujang Siti Mariam , Subramaniam Ponnusamy , Yahya Hanieza Fadzlina , Chan Lai Fong 
Published: January 2023

BackgroundSuicide is a major cause of death among adolescents and young adults, especially students. This is particularly true for healthcare students with a higher risk and more access to lethal means. Thus, it is vital for healthcare educators who have regular contact with these healthcare students to be trained as gatekeepers in preventing suicide. Evidence of the effectiveness of such gatekeeper training, mainly using an online module, is lacking predominantly in Malaysia. This study aims to investigate the effectiveness of an online gatekeeper suicide prevention training program that is conducted for healthcare lecturers.MethodsA single-arm interventional pre-and post-pilot study was conducted on a sample of healthcare lecturers and workers who are involved in supervising healthcare students. A purposive sampling technique was used to recruit 50 healthcare educators in Malaysia. The program was conducted by trained facilitators and 31 participants completed a locally validated self-rated questionnaire to measure their self-efficacy and declarative knowledge in preventing suicide; immediately before and after the intervention.ResultsSignificant improvement was seen in the overall outcome following the intervention, mostly in the self-efficacy domain. No significant improvement was seen in the domain of declarative knowledge possibly due to ceiling effects; an already high baseline knowledge about suicide among healthcare workers. This is an exception in a single item that assesses a common misperception in assessing suicide risk where significant improvement was seen following the program.ConclusionThe online Advanced C.A.R.E. Suicide Prevention Gatekeeper Training Program is promising in the short-term overall improvement in suicide prevention, primarily in self-efficacy.
A meta-analytic review of the associations between dimensions of religious coping and psychological symptoms during the first wave of the COVID-19 pandemic
Authors: Cheng Cecilia , Ying Weijun 
Published: January 2023

IntroductionIn the first wave of the COVID-19 pandemic, the unknown etiology and treatment of the highly transmissible coronavirus posed considerable threats to public mental health. Many people around the globe turned to religion as an attempt to mitigate their heightened psychological distress, but mixed findings have been obtained regarding the association between the use of religious coping and two psychological symptoms—anxiety and depressive symptoms—widely reported in the initial wave.ObjectiveThe present meta-analysis was conducted to resolve the empirical inconsistency by synthesizing this body of studies and identifying both individual and national-level factors that accounted for the inconsistent findings.MethodsFollowing PRISMA guidelines, the literature search and data screening procedures yielded 42 eligible studies, with 25,438 participants (58% females, average age = 36.50 years) from 24 countries spanning seven world regions.ResultsOverall, the results showed that only negative religious coping was positively associated with psychological symptoms (r= 0.2886,p&lt; 0.0001). Although the associations of both general and positive religious coping with psychological symptoms were non-significant (rs = 0.0425 and −0.0240,ps &gt; 0.39), the moderation analysis revealed significant positive associations between positive religious coping and psychological symptoms in two demographic groups who experienced greater pandemic distress than their counterparts: younger participants and female participants.DiscussionThis meta-analysis provides a nuanced understanding of the complex nature of religious coping in the initial wave of the COVID-19 pandemic when the levels of public anxiety and stress were heightened. The exclusive use of religious coping may not be associated with low levels of psychological symptoms, implying the importance of supplementing the deployment of this strategy with an array of other strategies. Therapists of mental health interventions should show their clients how to make good use of positive religious coping together with other strategies, and how to avoid the use of negative religious coping, to handle their psychological problems.Systematic review registrationhttps://osf.io/shb32/
The impact of psychological capital on green and organizational performance: Empirical research measuring psychological and subjective health of green building industries
Authors: Chen Si-Xu , Tang Yuan 
Published: January 2023

IntroductionGreen building (GB) technologies have been introduced to reduce the negative effect of the building and construction industry on the economy, the ecosystem, and society. A more thorough and accurate knowledge of the factors for implementation is required to stimulate the wider adoption of GB technologies. The theoretical framework for this study is developed using psychological capital (PC), self-determination theory (SDT), and green theory. The study addresses gaps in the research in this field. The effect of PC on psychological health (PH), green innovation ambidexterity (GIA), and subjective health (SH), and the impact of GIA on green performance (GP) are determined. The effect of PH and SH on organizational performance (OP) is also determined.MethodsThe information for this study is collected from a variety of sources in the Chinese GB industry. The subjects for this study are Chinese employees of GB-based companies. Using a convenience sampling method, a total of 504 employees were selected. The employees' answers to a restricted, self-administered survey are used to generate the data.ResultsData from this study shows that PC has a significant effect on GIA, SH, and PH and that GIA has a substantial impact on GP. Both SH and PH significantly affect OP.DiscussionThis study encourages managers in the green building industry to support fresh concepts in order to gain a competitive edge by implementing and promoting innovative cultures, especially in terms of service delivery and customer understanding, because innovation plays a critical role in these industries.
The prevalence and county-level socioeconomic correlates of visual impairment and glasses ownership among rural students in Western China
Authors: Guan Hongyu , Zhang Yunyun , Wang Zhijie , Chen Xiangzhe , Xue Jing , Ding Yuxiu 
Published: January 2023

ObjectivesVision health has been a major issue in public health care. The vision problems of children in rural China are of particular concern. Effective policies for children's vision health should consider the heterogeneity of individual health levels and regional differences in healthcare services. This study systematically explored the relationship of student visual impairment and glasses ownership with county-level socioeconomic status (namely, county-level per capita GDP, population density and industrial structure) in rural China.MethodsThe study sample included 99,670 students in grades 4–9 from 445 schools in 13 counties in Shaanxi Province. From 2014 to 2020, students took school-based vision screening tests and completed sociodemographic questionnaires. Multivariate regressions were used for empirical analysis.ResultsThe prevalence of visual impairment was 30.4% in the total sample, and the rate of visual impairment in girls (34.3%) was higher than that in boys (27.0%). Among visually impaired students, the rate of glasses ownership was only 39.7%, with girls (40.6%) higher than boys (38.8%). The study also found that the visual impairment was significantly correlated with county-level average income, population density and industrial structure, and the glasses ownership was significantly correlated with population density and industrial structure (all p &lt; 0.001).ConclusionsThe study found that the county-level socioeconomic status was positively and significantly correlated with visual impairment and glasses ownership, respectively. The vision health management services for students should be jointly carried out by the education, medical and public health departments, and additional investment is needed to increase the accessibility and affordability of vision care services, with special focus on poor regions and disadvantaged groups, so as to narrow the gap in vision health services.
The regional implications of just transition in the world's most coal-dependent economy: The case of Mpumalanga, South Africa
Authors: Nel Etienne , Marais Lochner , Mqotyana Zolile 
Published: January 2023

IntroductionSouth Africa has had an extraordinarily heavy reliance on coal to fuel its economy, and it is one of the highest carbon dioxide emitters per capita globally. Current moves aligned with COP26 and recently announced Western support for a Just Transition Partnership to support decarbonisation in South Africa and replace coal fired power stations with renewables are to be welcomed. That said, the majority of South Africa's coal mines, thermal power stations and the currently important coal export industry are located in Mpumalanga's Coal-Belt, an area which has and will continue to experience significant social and economic trauma as mines close and workers needs to be reskilled. There are currently over 100,000 workers in the coal and related industries in this region.MethodsThis paper draws on international and South African evidence of the effects and responses to mine closure, regional resilience theory and evolutionary economic geography theory to analyse the implications and prospects for economic renewal as the coal industry winds down. Evidence is sourced form secondary material including government and industry policy statements and media articles, while primary material was sourced from key informant interviews.ResultsTransitioning this region of South Africa from its virtual mono-economy based on coal presents challenges which this paper highlights. While support from international sources to help make this transition into renewables will be of considerable benefit, significant challenges need to be addressed to ensure that difficulties are overcome, and the risks of the resource curse experienced in many developing countries are minimized.DiscussionProcesses may need to be put in place to ensure that the ambitious goal of transitioning from coal to renewables can be achieved, finances and management well-targeted, and a sense of security given to outside investors to help fund the transition, but also broader economic diversification. In parallel to ensure the “transition is just” mechanisms also need to be put in place, by the state and the investors, to ensure that those citizens unable to transition are empowered and engaged in their community to stem the risk of the inevitable frustration and social disturbance that exclusion from the economy and living with declining services creates. Whom should be putting these processes into place also needs consideration given that existing organizations are already struggling. Though not an easy task, it is hoped that this paper sheds some light on the various issues and encourages consideration of the ways to address them.
Factors related to the postoperative recurrence of lumbar disc herniation treated by percutaneous transforaminal endoscopy: A meta-analysis
Authors: Li Honglin , Deng Wei , Wei Faqiang , Zhang Liangmin , Chen Fan 
Published: January 2023

ObjectiveTo explore factors related to the postoperative recurrence of lumbar disc herniation treated by percutaneous transforaminal endoscopy.MethodsPubMed, EMBASE, Cochrane Library, CNKI, Wanfang database and VIP database were systematically searched from the time of each library's construction to October 20, 2022. The studies that compared the influencing factors of recurrent lumbar disc herniation were included based on the PICO search structure. The Newcastle–Ottawa Scale was used to evaluate the quality of observational studies. The effects of the patient's age, gender, BMI, smoking, drinking, hypertension, diabetes, course of the disease, Pfirrmann grade, and the surgical segment on recurrent lumbar disc herniation were systematically evaluated using Revman 5.3. The odds ratio (OR) and 95% confidence interval (CI) were calculated.ResultsThirteen studies involving 3,393 patients (323 patients with recurrent lumbar disc herniation) treated with percutaneous transforaminal endoscopy were included in this study. The results of the systematic evaluation showed that the effects of gender, smoking, drinking, hypertension, type of lumbar disc herniation and the surgical segment on recurrent lumbar disc herniation were not statistically significant. However, age ≥60 years (OR = 2.23; 95% CI: 1.13, 4.41), BMI ≥25 (OR = 2.89; 95% CI: 1.23, 6.80), diabetes (OR = 1.73; 95% CI: 1.18, 2.55), course of disease ≥4 years (OR = 2.93; 95% CI: 1.58, 5.43), Pfirrmann grades 3–4 (OR = 3.10; 95% CI: 2.18, 4.40), incomplete removal of nucleus pulposus (OR = 3.26; 95% CI: 1.69, 6.27) and intraoperative fibre breakage (OR = 3.18; 95% CI: 1.56, 6.50) increased the risk of recurrence after treatment.ConclusionThe recurrence of lumbar disc herniation after percutaneous transforaminal endoscopic treatment is related to demographic characteristics, disease history and surgical conditions. In the future, more high-quality studies are needed to explore the influencing factors of recurrent lumbar disc herniation.
High expression of TMEM200A is associated with a poor prognosis and immune infiltration in gastric cancer
Authors: Deng Hongyang , Li Tengfei , Wei Fengxian , Han Wei , Xu Xiaodong , Zhang Youcheng 
Published: January 2023

Background: Gastric cancer (GC) is one of the global malignant tumors with high incidence and poor prognosis. Exploring new GC molecular markers is important to improve GC prognosis. Transmembrane protein 200A (TMEM200A) is a member of the family of transmembrane proteins (TMEM). This study is the first to investigate the potential function of TMEM200A and its relationship with immune infiltration in GC.Methods: The differential expression of TMEM200A was determined through the Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. The receiver operating characteristic (ROC) curve was drawn to assess the diagnostic value of TMEM200A for GC. The relationship between TMEM200A and the clinical characteristics of patients with GC was investigated using the Wilcoxon test and the Kruskal-Wallis test. The effect of TMEM200A on overall survival (OS) was identified using the Kaplan-Meier method, the Log-rank test, the univariate/multivariate Cox regression analysis, and the nomogram prediction model. The co-expressed genes and gene set enrichment analysis (GSEA) were used to explore the potential biological functions of TMEM200A. We used the Tumor Immune Estimation Resource (TIMER) database and the ssGSEA algorithm to estimate the relationship between TMEM200A and immune cell infiltration. Furthermore, we investigated the correlation of TMEM200A with immune checkpoint/immune cell surface markers using the TCGA-STAD data set. Finally, we identified prognosis-related methylation sites in TMEM200A using MethSurv.Results: TMEM200A was highly expressed in GC tissues. TMEM200A had a good diagnostic value for GC. High expression of TMEM200A may shorten the OS of GC patients and may be an independent risk factor for OS in GC patients. TMEM200A participates in the construction of a predictive model with a good predictive effect on the survival rate of GC patients at 1, 3, and 5 years. Co-expressed genes and GSEA indicated that TMEM200A may be an adhesion molecule closely associated with tumor invasion and metastasis. In addition, TMEM200A may be significantly associated with immune cell infiltration and immune checkpoint expression. We also found that TMEM200A contains three methylation sites associated with a poor prognosis.Conclusion: Upregulated TMEM200A may be a promising prognostic marker for GC and is closely associated with the tumor microenvironment (TME).
Genome-Wide Identification of Kiwifruit SGR Family Members and Functional Characterization of SGR2 Protein for Chlorophyll Degradation
Authors: Luo Juan , Abid Muhammad , Zhang Yi , Cai Xinxia , Tu Jing , Gao Puxin , Wang Zupeng , Huang Hongwen 
Published: January 2023

The STAY-GREEN (SGR) proteins play an important role in chlorophyll (Chl) degradation and are closely related to plant photosynthesis. However, the availability of inadequate studies on SGR motivated us to conduct a comprehensive study on the identification and functional dissection of SGR superfamily members in kiwifruit. Here, we identified five SGR genes for each of the kiwifruit species [Actinidia chinensis (Ac) and Actinidia eriantha (Ae)]. The phylogenetic analysis showed that the kiwifruit SGR superfamily members were divided into two subfamilies the SGR subfamily and the SGRL subfamily. The results of transcriptome data and RT-qPCR showed that the expression of the kiwifruit SGRs was closely related to light and plant developmental stages (regulated by plant growth regulators), which were further supported by the presence of light and the plant hormone-responsive cis-regulatory element in the promoter region. The subcellular localization analysis of the AcSGR2 protein confirmed its localization in the chloroplast. The Fv/Fm, SPAD value, and Chl contents were decreased in overexpressed AcSGR2, but varied in different cultivars of A. chinensis. The sequence analysis showed significant differences within AcSGR2 proteins. Our findings provide valuable insights into the characteristics and evolutionary patterns of SGR genes in kiwifruit, and shall assist kiwifruit breeders to enhance cultivar development.
Progress and Prospects of the Molecular Basis of Soybean Cold Tolerance
Authors: Tsegaw Mesfin , Zegeye Workie Anley , Jiang Bingjun , Sun Shi , Yuan Shan , Han Tianfu , Wu Tingting 
Published: January 2023

Cold stress is a major factor influencing the geographical distribution of soybean growth and causes immense losses in productivity. Understanding the molecular mechanisms that the soybean has undergone to survive cold temperatures will have immense value in improving soybean cold tolerance. This review focuses on the molecular mechanisms involved in soybean response to cold. We summarized the recent studies on soybean cold-tolerant quantitative trait loci (QTLs), transcription factors, associated cold-regulated (COR) genes, and the regulatory pathways in response to cold stress. Cold-tolerant QTLs were found to be overlapped with the genomic region of maturity loci of E1, E3, E4, pubescence color locus of T, stem growth habit gene locus of Dt1, and leaf shape locus of Ln, indicating that pleiotropic loci may control multiple traits, including cold tolerance. The C-repeat responsive element binding factors (CBFs) are evolutionarily conserved across species. The expression of most GmDREB1s was upregulated by cold stress and overexpression of GmDREB1B;1 in soybean protoplast, and transgenic Arabidopsis plants can increase the expression of genes with the DRE core motif in their promoter regions under cold stress. Other soybean cold-responsive regulators, such as GmMYBJ1, GmNEK1, GmZF1, GmbZIP, GmTCF1a, SCOF-1 and so on, enhance cold tolerance by regulating the expression of COR genes in transgenic Arabidopsis. CBF-dependent and CBF-independent pathways are cross-talking and work together to activate cold stress gene expression. Even though it requires further dissection for precise understanding, the function of soybean cold-responsive transcription factors and associated COR genes studied in Arabidopsis shed light on the molecular mechanism of cold responses in soybeans and other crops. Furthermore, the findings may also provide practical applications for breeding cold-tolerant soybean varieties in high-latitude and high-altitude regions.
Doença de crohn: uma revisão da literatura
Authors: Franco Carlos Augusto Santos , Marques Sílvia Fernanda Pereira , Gomes Eriston Vieira 
Published: January 2023

Introdução: A Doença de Crohn (DC) foi descrita no ano de 1932 pelo Dr Burril B. Crohn na cidade de Nova York. Trata-se de uma condição inflamatória afetando o sistema digestivo, principalmente íleo e cólon intestinais. Acomete de maneira difusa o trato gastrointestinal, podendo gerar estenose, fístula e perfuração. Há, portanto, uma alteração do mecanismo de controle do sistema imune da mucosa intestinal, aumentando de maneira significativa os sinais pró-inflamatórios e consequentemente danos teciduais. Metodologia: Foi realizada uma revisão narrativa da literatura com o intuito de abordar a história da doença de Crohn e sua fisiopatologia. Resultado: A DC, também denominada de colite granulomatosa, é capaz de afetar o sistema digestivo, desde a boca ao ânus, acometendo mais frequentemente o íleo e cólon intestinal, além de manifestar em outros órgãos proximais. As partes afetadas possuem aspecto de paralelepípedos intercalados por segmentos sadios. Tal condição decorre da integração entre fatores genéticos, ambientais e enteropatógenos que modificam a microbiota intestinal do indivíduo acometido. Consequentemente, sinais e sintomas como cólica abdominal, diarreia, perda ponderal, êmese e febre são notáveis. A doença se desenvolve de maneira lenta e progressiva, afetando, principalmente, os homens. Na DC, ocorrem alterações no intestino delgado, provenientes do processo inflamatório tais como obstrução e edema, formando uma parede intestinal espessa, com passagem mais estreita. Em casos de obstrução em alça fechada, é recomendado o tratamento cirúrgico imediato. Conclusão: A partir do reconhecimento das características físicas e clínicas da DC, é possível obter um diagnóstico precoce e assertivo, consequentemente, uma intervenção e tratamento adequados e melhor qualidade de vida ao paciente.
Nutrient and energy intake of modern university students
Authors: Gritsina O. P. , Yatsenko A. K. , Trankovskaya L. V. , Tarasenko G. A. , Mironenko Yu. K. , Sheparev A.  A. , Kovalchuk V. K. 
Published: January 2023

Aim. To study the nutrient and energy intake of modern university students. Materials and methods. 244 students aged 18–23 enrolled in specialist degree programmes were surveyed using a 24-hour dietary recall method adapted for online Google form surveying. The food intake was analysed based on the following aspects: meal frequency, intervals between meals and energy intake.Results. According to the obtained results, 38.93 ± 3.12% of the respondents follow a 3–4 meal-a-day diet, with 3 main meals (breakfast, lunch and dinner) adhered by 71.31 ± 2.9% of students. In comparison with male respondents, female students were found to be more likely to keep main meals (74.87 ± 3.17% versus 59.65 ± 6.50%, χ2 = 4.94, p = 0.027). Additional meals (second breakfast, afternoon tea, overnight snack) were observed in 64.75 ± 3.06% of the students, with this share being significantly larger among male students (78.95 ± 5.40% versus 60.43 ± 3.58%, χ2 = 6.56, p = 0.011). About 68.44 ± 2.98% of the respondents reported long intervals between meals, which was found to be more typical of female students (71.66 ± 3.30% versus 56.14 ± 6.57%, χ2 = 4.84, p = 0.028). The energy intake of young people was established to correspond to the recommended norm in 27.40 ± 3.69% of cases.Conclusions. The findings emphasize the importance of developing healthy eating habits in modern students, which can contribute to improving their health and increasing their educational performance.