bluuebunny/crossref_metadata_2025_split huggingface dataset:
Accurate Optical Metrology of van der Waals Monolayers and Heterostructures from the Interference of Interface Polariton Waves
Authors: Qin Kang , Zuo Zong‐yan , Peng Sheng , Liu Kai , Yang Hui , Zhang Qi‐hang , Lu Yan‐qing , Zhu Yong‐yuan , Zhang Xue‐jin 
Published: August 2023

AbstractNew two‐dimensional (2D) van der Waals materials are emerging, and their optical parameters urgently need to be acquired experimentally. Most of the reported results come from traditional metrologies used in the past for bulk materials. This unavoidably causes controversy regarding the correctness and accuracy of results, as well as the physical model. Surface/interface plasmon polariton waves are sub‐diffraction‐limited and very sensitive to surroundings. Here, 2D van der Waals materials with metal embodied are presented. Surface/interface exciton‐plasmon polaritons come into being with excitons in 2D transition‐metal dichalcogenides (TMDCs), which are physically taken as the boundary conditions with complex optical conductivities at the interfaces. Complex optical conductivities of 2D TMDCs are measured by means of interference behavior of surface/interface polariton waves. The size requirement of 2D van der Waals materials becomes relaxed, and complex optical conductivities can be measured for single‐crystalline WS2 and MoS2 monolayers with small sizes. Furthermore, a remarkable capability is manifested by yielding complex optical conductivity of van der Waals heterostructures. The proposed metrology can apply to other newly developed materials with modified underlying physical models, as well as various types of 2D van der Waals materials.
Spiro Boron‐Nitrogen Molecules Based Thermally Activated Delayed Fluorescence Emitter for Highly Efficient Solution‐Processed Organic Light‐Emitting Diodes
Authors: Liao Guanming , Lei Jinyu , Li Shuxin , Liu Meiyan , Qiao Yali , Liu Kanglei , Wang Nan , Niu Quan , Yin Xiaodong 
Published: August 2023

AbstractSpiro compounds with unique structural and electronic properties are beneficial for thermally activated delayed fluorescence (TADF) emitters. Herein, a series of spiro boron‐nitrogen (B‐N) compounds are reported with donor–acceptor (D‐A) interaction through homoconjugation. Three phenyl acridine‐containing spiro B‐N compounds exhibit highly efficient photoluminescence (PL) in degassed toluene and solid‐state with obvious TADF character. The separation of HOMO and LUMO for these compounds is confirmed by theoretical calculations, as is the small ΔEST of phenyl acridine‐containing compounds. These three compounds are used as emitting layers in solution‐processed organic light‐emitting diodes (OLEDs), resulting in deep‐blue to green emission colors with different acceptor moieties. Impressively, an excellent external quantum efficiency (EQE) of 22.1% is recorded for the TPA‐s‐FMesBF‐based OLED device, which is comparable with the highest value from solution‐processed OLEDs based on spiro D‐A emitting materials. This work presents a facile synthetic route to novel B, N‐substituted spiro compounds, as well as the structure‐property relationship of spiro D‐A compounds for highly efficient TADF emitters.
A Versatile Synthetic Method for Photophysically and Chemically Stable [5]Rotaxane‐Type Fluorescence Dyes of Various Colors by Using a Cooperative Capture Strategy
Authors: Ohishi Yuki , Nishioki Kohei , Miyaoka Yuta , Serizawa Keita , Sugawara Souma , Hayashi Koichiro , Inoue Daichi , Iwamura Munetaka , Yokoyama Satoru , Chiba Junya , Inouye Masahiko 
Published: August 2023

AbstractRotaxane‐type fluorescence dyes promise applications of optical and biological interest because their inner fluorescence cores are protected in inseparable host–guest systems. However, there are few relevant reports of such rotaxane‐type fluorescence dyes due to the difficulty of their syntheses. Here, a versatile synthetic method is established for [5]rotaxane‐type fluorescence dyes by employing a cooperative capture strategy. Using this method, [5]rotaxanes with emission colors ranging from blue to red are synthesized successfully. These [5]rotaxanes show higher emission quantum yields than the corresponding naked fluorescence dyes in water and even in the solid state. Furthermore, these rotaxanes show photostability and chemical stability, demonstrating the high applicability of [5]rotaxane‐type fluorescence dyes for a variety of emitting materials.
Amorphous/Crystal Heterostructure Coupled Oxygen Vacancies‐Sensitized TiO2 with Conspicuous Charge‐Transfer Resonance for Efficient SERS Detection of Chloramphenicol
Authors: Quan Yingnan , Tang Xiang‐Hu , Lu Wenjing , Huo Wang , Song Zongyin , Shen Wei , Yang Meng , Huang Xing‐Jiu , Liu Wen‐Qing 
Published: August 2023

AbstractAntibiotic environmental pollutants, such as chloramphenicol (CAP), have attracted global attention. They usually show a complex background, low concentration, and weak chemical activity in water bodies, making their rapid and on‐site detection a scientific challenge. Surface‐enhanced Raman spectroscopy (SERS) technology can facilitate the practical application of CAP detection; however, it is important to match substrate materials with excellent SERS properties. The most challenging aspect of SERS substrate design is the realization of energy level matching and charge‐transfer resonance. Herein, a crystal‐amorphous TiO2 substrate material rich in oxygen vacancies, CA‐V‐TiO2, is proposed. Through the cooperative regulation of vacancies and amorphous state, the bandgap structure can be optimized, the charge‐transfer efficiency can be improved, and finally the energy level matching between CA‐V‐TiO2 substrate and molecules can be realized and the conspicuous charge‐transfer resonance phenomenon can be generated, effectively optimizing the performance of SERS substrate. In addition, CA‐V‐TiO2 substrate is used for sensitive detection of CAP, showing multiple advantages such as low detection limit, good reproducibility, and high stability, which can realize trace CAP detection in actual water environments. This work provides a reliable platform for SERS on‐site detection of CAP in the field of food and environmental monitoring.
Nitric Oxide: Physiological Functions, Delivery, and Biomedical Applications
Authors: Andrabi Syed Muntazir , Sharma Navatha Shree , Karan Anik , Shahriar S. M. Shatil , Cordon Brent , Ma Bing , Xie Jingwei 
Published: August 2023

AbstractNitric oxide (NO) is a gaseous molecule that has a central role in signaling pathways involved in numerous physiological processes (e.g., vasodilation, neurotransmission, inflammation, apoptosis, and tumor growth). Due to its gaseous form, NO has a short half‐life, and its physiology role is concentration dependent, often restricting its function to a target site. Providing NO from an external source is beneficial in promoting cellular functions and treatment of different pathological conditions. Hence, the multifaceted role of NO in physiology and pathology has garnered massive interest in developing strategies to deliver exogenous NO for the treatment of various regenerative and biomedical complexities. NO‐releasing platforms or donors capable of delivering NO in a controlled and sustained manner to target tissues or organs have advanced in the past few decades. This review article discusses in detail the generation of NO via the enzymatic functions of NO synthase as well as from NO donors and the multiple biological and pathological processes that NO modulates. The methods for incorporating of NO donors into diverse biomaterials including physical, chemical, or supramolecular techniques are summarized. Then, these NO‐releasing platforms are highlighted in terms of advancing treatment strategies for various medical problems.
Non‐Fermi‐Liquid Behavior of Superconducting SnH4
Authors: Troyan Ivan A. , Semenok Dmitrii V. , Ivanova Anna G. , Sadakov Andrey V. , Zhou Di , Kvashnin Alexander G. , Kruglov Ivan A. , Sobolevskiy Oleg A. , Lyubutina Marianna V. , Perekalin Dmitry S. , Helm Toni , Tozer Stanley W. , Bykov Maxim , Goncharov Alexander F. , Pudalov Vladimir M. , Lyubutin Igor S. 
Published: August 2023

AbstractThe chemical interaction of Sn with H2 by X‐ray diffraction methods at pressures of 180–210 GPa is studied. A previously unknown tetrahydride SnH4 with a cubic structure (fcc) exhibiting superconducting properties below TC = 72 K is obtained; the formation of a high molecular C2/m‐SnH14 superhydride and several lower hydrides, fcc SnH2, and C2‐Sn12H18, is also detected. The temperature dependence of critical current density JC(T) in SnH4 yields the superconducting gap 2Δ(0) = 21.6 meV at 180 GPa. SnH4 has unusual behavior in strong magnetic fields: B,T‐linear dependences of magnetoresistance and the upper critical magnetic field BC2(T) ∝ (TC – T). The latter contradicts the Wertheimer–Helfand–Hohenberg model developed for conventional superconductors. Along with this, the temperature dependence of electrical resistance of fcc SnH4 in non‐superconducting state exhibits a deviation from what is expected for phonon‐mediated scattering described by the Bloch‐Grüneisen model and is beyond the framework of the Fermi liquid theory. Such anomalies occur for many superhydrides, making them much closer to cuprates than previously believed.
Root Cause Analysis of Degradation in Protonic Ceramic Electrochemical Cell with Interfacial Electrical Sensors Using Data‐Driven Machine Learning
Authors: Wu Wei , Wang Congjian , Bian Wenjuan , Hua Bin , Gomez Joshua Y. , Orme Christopher J. , Tang Wei , Stewart Frederick F. , Ding Dong 
Published: August 2023

AbstractProtonic ceramic electrochemical cells (PCECs) offer promising paths for energy storage and conversion. Despite considerable achievements made, PCECs still face challenges such as physiochemical compatibility between componenets and suboptimal solid–solid contact at the interfaces between the electrolytes and electrodes. In this study, a novel approach is proposed that combines in situ electrochemical characterization of interfacial electrical sensor embedded PCECs and machine learning to quantify the contributions of different cell components to total degradation, as well as to predict the remaining useful life. The experimental results suggest that the overpotential induced by the oxygen electrode is 48% less than that of oxygen electrode/electrolyte interfacial contact for up to 1171 h. The data‐driven machine learning simulation predicts the RUL of up to 2132 h. The root cause of degradation is overpotential increase induced by oxygen electrode, which accounts for 82.9% of total cell degradation. The success of the failure diagnostic model is demonstrated by its consistency with degradation modes that do not manifest in electrolysis fade during early real operations. This synergistic approach provides valuable insights into practical failure diagnosis of PCECs and has the potential to revolutionize their development by enabling improved performance prediction and material selection for enhanced durability and efficiency.
Highly Efficient Photothermal Icephobic/de‐Icing MOF‐Based Micro and Nanostructured Surface
Authors: Zhang Lei , Luo Bingcai , Fu Kun , Gao Chunlei , Han Xuefeng , Zhou Maolin , Zhang Tiance , Zhong Lieshuang , Hou Yongping , Zheng Yongmei 
Published: August 2023

AbstractPhotothermal materials have gained considerable attention in the field of anti‐/de‐icing due to its environmental friendliness and energy saving. However, it is always significantly challenging to obtain solar thermal materials with hierarchical structure and simultaneously demonstrate both the ultra‐long icing delay ability and the superior photothermal de‐icing ability. Here, a photothermal icephobic MOF‐based micro and nanostructure surface (MOF‐MNS) is presented, which consists of micron groove structure and fluorinated MOF nanowhiskers. The optimal MOF‐M250NS can achieve solar absorption of over 98% and produce a high temperature increment of 65.5 °C under 1‐sun illumination. Such superior photothermal‐conversion mechanism of MOF‐M250NS is elucidated in depth. In addition, the MOF‐M250NS generates an ultra‐long icing delay time of ≈3960 s at −18 °C without solar illumination, achieving the longest delay time, which isn't reported before. Due to its excellent solar‐to‐heat conversation ability, accumulated ice and frost on MOF‐M250NS can be rapidly melted within 720 s under 1‐sun illumination and it also holds a high de‐icing rate of 5.8 kg m−2 h−1. MOF‐M250NS possesses the versatility of mechanical robustness, chemical stability, and low temperature self‐cleaning, which can synergistically reinforce the usage of icephobic surfaces in harsh conditions.
Regioselective Electrophilic Addition to Propargylic B(MIDA)s Enabled by β‐Boron Effect
Authors: Li Yin , Chen Zhi‐Hao , Lin Shuang , Liu Yuan , Qian Jiasheng , Li Qingjiang , Huang Zhi‐Shu , Wang Honggen 
Published: August 2023

AbstractElectrophilic addition reaction to alkynes is of fundamental importance in organic chemistry, yet the regiocontrol when reacting with unsymmetrical 1,2‐dialkyl substituted alkynes is often problematic. Herein, it is demonstrated that the rarely recognized β‐boron effect can confer a high level of site‐selectivity in several alkyne electrophilic addition reactions. A broad range of highly functionalized and complex organoborons are thus formed under simple reaction conditions starting from propargylic MIDA (N‐methyliminodiacetic acid) boronates. These products are demonstrated to be valuable building blocks in organic synthesis. In addition to the regiocontrol, this study also observes a drastic rate enhancement upon B(MIDA) substitution. Theoretical calculation reveals that the highest occupied molecular obital (HOMO) energy level of propargylic B(MIDA) is significantly raised by 0.3 eV, and the preferential electrophilic addition to the γ position is due to its higher HOMO orbital coefficient and more negative natural bond orbital (NBO) charge compared to the β position. This study demonstrates the potential of utilizing the β‐boron effect in stereoelectronic control of chemical transformations, which can inspire further research in this area.
Catalytic Undirected Meta‐Selective C–H Borylation of Metallocenes
Authors: Zheng Hao , Liu Chang‐Hui , Wang Xiao‐Yu , Liu Yan , Chen Bing‐Zhi , Hu Yan‐Cheng , Chen Qing‐An 
Published: August 2023

AbstractMetallocenes are privileged backbones in the fields of synthetic chemistry, catalysis, polymer science, etc. Direct C–H functionalization is undoubtedly the simplest approach for tuning the properties of metallocenes. However, owing to the presence of multiple identical C(sp2)‐H sites, this protocol often suffers from low reactivity and selectivity issues, especially for the regioselective synthesis of 1,3‐difunctionalized metallocenes. Herein, an efficient iridium‐catalyzed meta‐selective C–H borylation of metallocenes is reported. With no need of preinstalled directing groups, this approach enables a rapid synthesis of various boronic esters based on benzoferrocenes, ferrocenes, ruthenocene, and related half sandwich complex. A broad range of electron‐deficient and ‐rich functional groups are all compatible with the process. Notably, C–H borylation of benzoferrocenes takes place exclusively at the benzene ring, which is likely ascribed to the shielding effect of pentamethylcyclopentadiene. The synthetic utility is further demonstrated by easy scalability to gram quantities, the conversion of boron to heteroatoms including N3, SePh, and OAc, as well as diverse cross‐coupling reactions.
Beckwith–Wiedemann syndrome with multiple hepatic and cutaneous hemangiomas in a female patient of Albanian origin: Diagnostic and therapeutic considerations
Authors: Moutafi Maria , Gkiourtzis Nikolaos , Ververi Athina , Kavga Maria , Morichovitou Anthi , Papadopoulou‐Legbelou Kyriaki , Fotoulaki Maria , Panagopoulou Paraskevi 
Published: August 2023

AbstractWe describe a 2‐month‐old female infant with macroglossia, macrosomia, omphalocele, neonatal hypoglycemia, earlobe creases, low nasal bridge, midface retrusion, syndromic facies and multiple cutaneous and hepatic hemangiomas (HH). Genetic evaluation confirmed the diagnosis of Beckwith–Wiedemann Syndrome (BWS) with mosaic uniparental disomy 11 as the underlying genetic mechanism suggested by partial hypermethylation of H19/IGF2:IG‐DMR and partial hypomethylation of KCNQ1OT1:TSS‐DMR on chromosome 11p15.5. Pediatric endocrinology and cardiology assessments were normal. No malignant liver or renal tumors were detected during the follow‐up period. Treatment with propranolol was started for the multiple HH, according to international recommendations. At 3‐, 6‐, and 9‐month follow up, a gradual decrease in the size of the hemangiomas and AFP levels was observed, without side effects. This is the fifth case in the literature combining HH and BWS, and among these, the third case with this specific genetic defect suggesting a possible association between HH and BWS caused by 11 paternal uniparental disomy [upd(11)pat]. The case also highlights that if treatment is warranted, then oral propranolol can be used for the management of infantile HH in BWS patients similarly to non‐BWS patients.
The Holocene record of the slow loris (Nycticebus sp.) in Java (Indonesia)
Authors: Gruwier Ben , Amano Noel 
Published: August 2023

AbstractObjectives(Sub)fossil lorises are rare in Southeast Asia. Their taxonomic relationship with extant populations, and the extent to which their distribution and morphology are influenced by changing environmental conditions, remains poorly understood. This study provides a synthesis of Nycticebus occurrences in Holocene Java. A morphometric analysis of a sample of craniodental remains aims to improve our understanding of their taxonomic status. Morphometrics were also used to explore potential size changes during the Holocene.Materials and MethodsBased on the literature and a review of museum catalogs, a synthesis was compiled of (sub)fossil slow loris occurrences in Java. Morphometric data on the mandible and maxilla of 10 (sub)fossil lorises were compared with a dataset of extant specimens to assess variation in size and shape.ResultsFive Holocene Nycticebus occurrences were identified in eastern Java. All specimens fall in the range of N. javanicus and N. coucang. The specimens from Hoekgrot, Gua Jimbe, and Sampung suggest an affinity to N. javanicus. The remains from Gua Jimbe and Hoekgrot gave values close to the largest N. javanicus specimens, but the (presumably older) Song Terus specimen was of average size.Discussion and ConclusionsThe distribution of Nycticebus suggests that it originally occurred throughout the island. The remains are probably best identified as N. javanicus or N. coucang, but the Neolithic finds from Hoekgrot and Gua Jimbe are presumably N. javanicus. Size variation in Nycticebus was clinal, but although some large specimens were present, no evidence was found for size diminution during the Holocene.
Rapid visualization molecular fluorescence detection of methicillin‐resistant Staphylococcus aureus using the multiplex MIRA‐qPCR method
Authors: Heng Pengfei , Shi Bo , Li Dongmei , Ou Hua , He Yang , Zhou Lili 
Published: August 2023

AbstractMultidrug‐resistant (MDR) bacterial infections constitute a major public health problem worldwide. A rapid method for the detection of methicillin‐resistant Staphylococcus aureus (MRSA) is critical for the timely prevention of bacterial infections and the accurate clinical use of drugs. The nuc and mecA genes are potentially indicative of MRSA infection and in this study, a multiplex molecular fluorescence multi‐enzyme isothermal rapid amplification visual assay was proposed and established. The method is capable of detecting MRSA at 17 min, 40°C amplification, and is well differentiated from common clinical bacteria in specific assays, with 500 colony‐forming units (CFU) mL−1 of MRSA detected under optimal conditions. This method has excellent diagnostic capabilities versus classical methods to detect clinical samples and shows potential in the identification of pathogenic microorganisms in a clinical setting.
Electrospinning of bovine serum albumin‐based nano‐fibers: From synthesis to medical prospects; Challenges and future directions
Authors: Hayat Minahil , Bukhari Sayyad Ali Raza , Irfan Muhammad 
Published: August 2023

AbstractBovine serum albumin (BSA) is a globular non‐glycoprotein that has gotten a lot of attention because of its unique properties like biocompatibility, biodegradability, non‐immunogenicity, non‐toxicity, and strong resemblance to the natural extracellular matrix (ECM). Given its robust mechanical properties, such as interfacial tension, conductivity, swelling resistance, and viscoelasticity, it can be concluded that it is an appropriate matrix for producing novel BSA‐based nanoconstructs. Thus, simple analytic methods are required for accurately detecting BSA as a model protein in medical sciences and healthcare. Furthermore, the characteristics mentioned above aid BSA in the electrospinning process, which results in fibers conjugated with other polymers. Electrospun synthesis has recently received much attention for its ability to produce stable, biomimicking, highly porous, 3D BSA‐derived nano‐fibers. As a result, BSA‐based nano‐fibers have achieved exclusive developments in the medical sector, such as tissue engineering for the remodeling of damaged tissue or organ repair by creating artificial ones. Meanwhile, they could be used as drug delivery systems (DDS) for target‐specific drug delivery, wound dressings, and so on. This study illustrates the structural and physicochemical properties of BSA and the determination of BSA using various methods, by citing recent reports and current developments in the medical field. Furthermore, current challenges and future directions are also highlighted.
A solid‐phase microextraction gas chromatography–mass spectrometry technique for urinary metabolomics of human samples infected with schistosomiasis—Case of the Okavango Delta, Botswana
Authors: Tawana‐Ndolo Sedireng M. , Zachariah Matshediso , Phaladze Nthabiseng A. , Sichilongo Kwenga F. 
Published: August 2023

AbstractWe present a GC–MS metabolomics workflow for analyzing metabolites in urine samples infected with schistosomiasis. Schistosomiasis, a neglected tropical disease, affects 85% of the global population, with the majority residing in Sub‐Saharan Africa. The workflow utilized in this study involved the utilization of the AMDIS freeware, Metab R for pre‐processing, and multivariate statistical classification through partial least squares‐discriminant analysis (PLS‐DA). This classification aimed to categorize volatile metabolites found in urine samples from humans infected with schistosomiasis. All samples were collected from individuals in Botswana. A solid‐phase microextraction–fused silica fiber was used to adsorb volatile metabolites from the urine samples and inserted into the GC–MS injection port for data acquisition. The acquired data were then subjected to AMDIS auto‐deconvolution, Metab R pre‐processing, and statistical evaluation for metabolite mining. A total of 12 metabolites, including 3‐chloropropionic acid and heptadecyl ester with an AMDIS match factor of 96% at an approximated amount of 0.35% and cyclohexylamine with an AMDIS match factor of 100% and approximated amount of 0.39%, were identified. PLS‐DA was used for the classification of the metabolites. The method showed good sensitivity and specificity as indicated by the receiver operating characteristic measured by the areas under the curves. Results indicated that metabolomics is a useful tool for mining metabolites because of the variance in metabolite composition of infected and non‐infected urine samples.