bluuebunny/crossref_metadata_2025_split huggingface dataset:
Taking Stock of Knowledge Transfer Studies: Finding Ways Forward
Authors: Lundmark Carina , Nilsson Jens , Krook-Riekkola Anna 
Published: September 2023

AbstractKnowledge transfer (KT) from academia to practice is important in many fields, but comprehensive studies on identifying the most effective forms of KT are scarce. This paper aims to provide an overview of KT theory and presents a cross-disciplinary scoping review of empirically oriented peer-reviewed articles. The review offers guidance for researchers seeking to communicate effectively with practitioners. It explores the effects of research communications, delves into the understanding and measurement of these effects, attempts to identify the most effective forms of communication, and highlights important considerations when designing KT strategies. Few studies in our sample (eight of 27) systematically measured effects of KT, and merely four studies compared multiple forms of KT. Nevertheless, most studies estimated effects from KT, regardless of the chosen form (e.g., workshops or lectures). Most studies estimated knowledge change as the primary outcome. Additionally, several studies explored altered beliefs such as increased self-efficacy. A third of the studies addressed how the knowledge was applied, ranging from sharing information to developing new habits. The identified effects were, however, both small and volatile. Our findings underscore the significance of continuity and repeated interactions to enhance the impact of KT initiatives. Furthermore, researchers need to develop a comprehensive set of tools to facilitate successful KT, considering factors such as expertise, communication skills, trust-building, and participant-centered approaches. By employing these strategies, researchers can effectively bridge the gap between academia and practice, facilitating successful KT in various fields.
Quantifying endolithic bioerosion rates on remote coral reefs in the Central Indian Ocean
Authors: Lloyd Newman Jake E. , Perry Chris T. , Lange Ines D. 
Published: September 2023

AbstractBioerosion of calcium carbonate is a fundamental process that impacts net coral reef accretion. Besides large grazers, endolithic organisms play a major role in carbonate removal. Here we provide the first rate data for both macro- and microendolithic bioerosion in the remote Chagos Archipelago, Indian Ocean. Based on analysis of experimental blocks using computer tomography, we show similar macrobioerosion rates at 5 m (0.086 ± 0.026 kg m−2 yr−1) compared to at 10 m depth (0.066 ± 0.016 kg m−2 yr−1) after three years of exposure, with a succession from worm to sponge bioeroders over time. Microbioerosion rates analysed with scanning electron microscopy were 2–5 × higher than macrobioerosion rates at 5 m (0.187 ± 0.028 kg m−2 yr−1) and 10 m depth (0.313 ± 0.049 kg m−2 yr−1), but the microborer community was dominated by cyanobacteria in all samples. Total endolithic erosion was small compared to external erosion by parrotfishes, which increased over time, but did not show significant differences between 5 m (0.74 ± 0.11) and 10 m depth (1.12 ± 0.16 kg m−2 yr−1) after three years of exposure. These erosion rates are indicative of the oligotrophic and remote reef setting in the Chagos Archipelago (clear water, low nutrients, high fish biomass). The data will help to improve local carbonate budget estimates and provide a context for wider regional and environmental comparisons.
Spina bifida and cardiorespiratory profile: the impact of leisure sport activities on physical fitness
Authors: Monti Riccardo , Mariani Francesco , Mastricci Rosanna , Nifosì Francesco Maria , Palmieri Vincenzo , Manes Gravina Ester , Capriati Margherita , Rendeli Claudia 
Published: September 2023

Abstract
Purpose
The aim of the present study is to evaluate a population of young patients affected by Spina Bifida (SB) to describe their cardiorespiratory function and bone mineral density profile, analyzing any differences between people performing and those who do not perform sports activity. The study also aimed to rule out possible congenital heart disease associated with spina bifida, considering the common origin of certain cardiac structures with those found to be altered in SB patients.

Methods
Thirty-four young patients, aged between 12 and 22 years, diagnosed with spinal dysraphism (SD), have been clinically described and, in order to evaluate their physical fitness, functional capacity and bone mass, almost all of them underwent a complete cardiorespiratory assessment, including electrocardiogram (ECG), echocardiogram, Cardiopulmonary Exercise Test (CPET), body composition analysis using bioimpedance analysis (BIA) and Dual Energy X-ray Absorptiometry (DEXA), as well as the estimation of bone mineral density (BMD) with Computerized Bone Mineralometry (CBM).

Results
Collected data demonstrated that only 35% of the subjects practiced physical activity during the week. BMI and percentage FM values were pathological in at least 50% of the population. On cardiological investigations (ECG and echocardiogram), no significant alterations were found. In all patients who performed CPET (79.4%), pathological values of the main functional capacity parameters were revealed, especially peak oxygen consumption (VO2 peak), even when corrected for BCM or FFM estimated at BIA and DEXA, respectively. In the CBM analysis, out of 27 patients in whom the femoral T-score was evaluated, a condition of osteopenia was revealed in 40.7% of the patients (11/27) and osteoporosis in 18.5% (5/27); out of 27 patients in whom the lumbar T-score was evaluated, 37% of the patients showed osteopenia (10/27) and 29.6% osteoporosis (8/27). When the comparison between exercising and non-exercising patients was performed, the only statistically significant difference that emerged was the median lumbar T-score value, which appeared lower in the group not performing physical activity (p = 0,009).

Conclusions
The extensive cardiorespiratory evaluation, including CPET, of our cohort of spina bifida patients showed altered values of the main parameters related to cardiorespiratory fitness and is the only study in the literature that analysed bone mineralization values in physically active and sedentary spina bifida patients and demonstrated a statistically significant difference. Furthermore, it is the only study to date that investigated the possible association of congenital heart diseases with SD, without demonstrating the existence of pathological conditions.
SLA2 is a prognostic marker in HNSCC and correlates with immune cell infiltration in the tumor microenvironment
Authors: Wu Zhongbiao , You Chengkun , Zhu Zhongyan , Wu Weikun , Cao Jian , Xie Qiang , Deng Chengcheng , Huang Xinmei , Hu Shiping 
Published: September 2023

Abstract
Purpose
To investigate Src-like adaptor 2 gene (SLA2) expression in head and neck squamous cell carcinoma (HNSCC), its potential prognostic value, and its effect on immune cell infiltration.

Methods
Through a variety of bioinformatics analyses, we extracted and analyzed data sets from the Cancer Genome Atlas (TCGA), Tumor Immune Estimation Resource (TIMER), and Gene Expression Profile Interaction Analysis (GEPIA) to analyze the correlation between SLA2 and the prognosis, immune checkpoint, tumor microenvironment (TME) and immune cell infiltration of HNSCC, and to explore its potential oncogenic mechanism. To further explore the potential role of SLA2 in HNSCC by Gene ontology (GO) functional annotation and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis.

Results
SLA2 messenger ribonucleic acid (mRNA) levels were increased in HNSCC tumor tissues compared with normal tissues. In addition, we found that SLA2 may be an independent prognostic factor for HNSCC, and high SLA2 expression is associated with favorable prognosis in HNSCC. SLA2 expression was positively correlated with B cells, cluster of differentiation 8-positive T cells (CD8 + T cells), cluster of differentiation 4-positive T cells (CD4 + T cells), macrophages, neutrophil and dendritic cells infiltration. SLA2 has also been shown to co-express immune-related genes and immune checkpoints. Significant GO term analysis by Gene Set Enrichment Analysis (GSEA) indicated that genes correlated with SLA2 were located mainly in the side of membrane, receptor complex, secretory granule membrane, endocytic vesicle, membrane region, and endosome membrane, where they were involved in leukocyte cell–cell adhesion, response to interferon-gamma, and regulation of immune effector process. These related genes also served as antigen binding, cytokine receptor activity, phosphatidylinositol 3-kinase activity, peptide receptor activity, Src homology domain 3 (SH3) domain binding, and cytokine receptor binding. KEGG pathway analysis demonstrated that these genes related to SLA2 were mainly enriched in signal pathways, such as hematopoietic cell lineage, cell adhesion molecules (CAMs), natural killer cell mediated cytotoxicity, measles, and chemokine signaling pathway.

Conclusions
SLA2 is increased in HNSCC, and high SLA2 expression is associated with favorable prognosis. SLA2 may affect tumor development by regulating tumor infiltrating cells in TME. SLA2 may be a potential target for immunotherapy.
Biphenyls and dibenzofurans of the rosaceous subtribe Malinae and their role as phytoalexins
Authors: Busnena Belnaser A. , Beerhues Ludger , Liu Benye 
Published: September 2023

Abstract
Main conclusion
Biphenyl and dibenzofuran phytoalexins are differentially distributed among species of the rosaceous subtribe Malinae, which includes apple and pear, and exhibit varying inhibitory activity against phytopathogenic microorganisms.

Abstract
Biphenyls and dibenzofurans are specialized metabolites, which are formed in species of the rosaceous subtribe Malinae upon elicitation by biotic and abiotic inducers. The subtribe Malinae (previously Pyrinae) comprises approximately 1000 species, which include economically important fruit trees such as apple and pear. The present review summarizes the current status of knowledge of biphenyls and dibenzofurans in the Malinae, mainly focusing on their role as phytoalexins. To date, 46 biphenyls and 41 dibenzofurans have been detected in 44 Malinae species. Structurally, 54 simple molecules, 23 glycosidic compounds and 10 miscellaneous structures were identified. Functionally, 21 biphenyls and 21 dibenzofurans were demonstrated to be phytoalexins. Furthermore, their distribution in species of the Malinae, inhibitory activities against phytopathogens, and structure–activity relationships were studied. The most widely distributed phytoalexins of the Malinae are the three biphenyls aucuparin (3), 2ʹ-methoxyaucuparin (7), and 4ʹ-methoxyaucuparin (9) and the three dibenzofurans α-cotonefuran (47), γ-cotonefuran (49), and eriobofuran (53). The formation of biphenyl and dibenzofuran phytoalexins appears to be an essential defense weapon of the Malinae against various stresses. Manipulating phytoalexin formation may enhance the disease resistance in economically important fruit trees. However, this approach requires an extensive understanding of how the compounds are formed. Although the biosynthesis of biphenyls was partially elucidated, formation of dibenzofurans remains largely unclear. Thus, further efforts have to be made to gain deeper insight into the distribution, function, and metabolism of biphenyls and dibenzofurans in the Malinae.
Ecosystem engineering and leaf quality together affect arthropod community structure and diversity on white oak (Quercus alba L.)
Authors: Reinhardt Jason R. , Marquis Robert J. 
Published: September 2023

AbstractShelter building caterpillars act as ecosystem engineers by creating and maintaining leaf shelters, which are then colonized by other arthropods. Foliage quality has been shown to influence initial colonization by shelter-building caterpillars. However, the effects of plant quality on the interactions between ecosystem engineers and their communities have yet to be studied at the whole plant level. We examined how leaf tying caterpillars, as ecosystem engineers, impact arthropod communities on Quercus alba (white oak), and the modifying effect of foliage quality on these interactions. We removed all leaf tying caterpillars and leaf ties on 35 Q. alba saplings during the season when leaf tying caterpillars were active (June–September), and compared these leaf tie removal trees to 35 control trees whose leaf ties were left intact. Removal of these ecosystem engineers had no impact on overall arthropod species richness, but reduced species diversity, and overall arthropod abundance and that of most guilds, and changed the structure of the arthropod community as the season progressed. There was an increase in plant-level species richness with increasing number of leaf ties, consistent with Habitat Diversity Hypothesis. In turn, total arthropod density, and that of both leaf tying caterpillars and free-feeding caterpillars were affected by foliar tannin and nitrogen concentrations, and leaf water content. The engineering effect was greatest on low quality plants, consistent with the Stress-Gradient Hypothesis. Our results demonstrate that interactions between ecosystem engineering and plant quality together determine community structure of arthropods on Q. alba in Missouri.
Implementation of the Enhanced Recovery After Surgery (ERAS®) program in neurosurgery
Authors: Belouaer Amani , Cossu Giulia , Papadakis Georgios E. , Gaudet John G. , Perez Maria-Helena , Chanez Vivianne , Boegli Yann , Mury Caroline , Peters David , Addor Valérie , Levivier Marc , Daniel Roy Thomas , Demartines Nicolas , Messerer Mahmoud 
Published: September 2023

Abstract
Background
Over the past decade, Enhanced Recovery After Surgery (ERAS®) guidelines have been proven to simplify postoperative care and improve recovery in several surgical disciplines. The authors set out to create and launch an ERAS® program for cranial neurosurgery that meets official ERAS® Society standards. The authors summarize the successive steps taken to achieve this goal in two specific neurosurgical conditions and describe the challenges they faced.

Methods
Pituitary neuroendocrine tumors (Pit-NET) resected by a transsphenoidal approach and craniosynostosis (Cs) repair were selected as appropriate targets for the implementation of ERAS® program in the Department of Neurosurgery. A multidisciplinary team with experience in managing these pathologies was created. A specialized ERAS® nurse coordinator was hired. An ERAS® certification process was performed involving 4 seminars separated by 3 active phases under the supervision of an ERAS® coach.

Results
The ERAS® Pit-NET team included 8 active members. The ERAS® Cs team included 12 active members. Through the ERAS® certification process, areas for improvement were identified, local protocols were written, and the ERAS® program was implemented. Patient-centered strategies were developed to increase compliance with the ERAS® protocols. A prospective database was designed for ongoing program evaluation. Certification was achieved in 18 months. Direct costs and time requirements are reported.

Conclusion
Successful ERAS® certification requires a committed multidisciplinary team, an ERAS® coach, and a dedicated nurse coordinator.
Solvothermal synthesis of cobalt PCP pincer complexes from [Co2(CO)8]
Authors: Schratzberger Heiko , Himmelbauer Daniel , Eder Wolfgang , Weiser Michael , Stöger Berthold , Kirchner Karl 
Published: September 2023

AbstractTreatment of [Co2(CO)8] with the ipso-substituted P(C-X)PY ligands (X = Br, Cl; R = iPr, tBu) bearing Y = NH and CH2 linkers under solvothermal conditions affords the five-coordinate Co(I) and Co(III) complexes [CoI(PCPY-R)(CO)2] and [CoIII(PCPY-R)X2]. The later are paramagnetic exhibiting a solution magnetic moment in the range of 3.0–3.3 μB which is consistent with a d6 intermediate spin system corresponding to two unpaired electrons. In the case of P(C-X)PY ligands (X = Br, Cl; R = tBu; Y = NH) the formation of the square planar Co(II) complex [Co(PCPNH-tBu)X] was favored. This complex gives rise to a magnetic moment of 1.8 μB being consistent with a d7 low spin system corresponding to one unpaired electron. All complexes are characterized by means of spectroscopic techniques (NMR, IR), HR-MS. Representative complexes were also characterized by X-ray crystallography.
Graphical abstract
River benthic macroinvertebrates and environmental DNA metabarcoding: a scoping review of eDNA sampling, extraction, amplification and sequencing methods
Authors: Vourka Aikaterini , Karaouzas Ioannis , Parmakelis Aristeidis 
Published: September 2023

AbstractThere is a growing body of literature on the use of molecular methods for the ecological assessment of rivers based on benthic macroinvertebrates. Previous research has established the benefits of the use of environmental DNA (eDNA) to assess benthic macroinvertebrate communities as being more efficient, less subjective, and non-invasive compared to traditional methods. The aim of this review is to synthesize the existing knowledge on eDNA sampling, extraction, amplification and sequencing methods regarding river benthic macroinvertebrate metabarcoding studies. Literature searches were performed using two online databases, and following a screening process, 46 papers published between 2012 and 2022 met the eligibility criteria to be included in the review. Since the use of river macrobial eDNA in ecology is a fast-evolving field, the results showed that the methodologies used vary considerably among studies. A variety of filters are used for capturing eDNA from water or preservative ethanol and different sources of eDNA (i.e., sediment, biofilm) are also explored. This review identified 12 different extraction methods and 15 different primer pairs that were used more than once in benthic macroinvertebrate eDNA metabarcoding studies. Therefore, there is a need for standardization of some key steps of the eDNA metabarcoding process to increase the comparability of the results and the robustness of the methods for further implementation into large-scale monitoring programs.
Resource recovery and reduction of tidal waste to produce cellulose through sulphur-free pulping
Authors: Moral Ana , Greyer Valeria , Aguado Roberto J. , Tijero Antonio 
Published: September 2023

AbstractThe transition towards a sustainable cellulose industry needs more environmentally friendly technologies, including the use of lignocellulosic waste as alternative raw materials. This work shows the potential of dead biomass from the Andalusian Mediterranean coastline to obtain cellulosic pulp. With this purpose, predominant species in onshore residues (mainly Posidonia oceanica) were prepared, characterized, and subjected to a soda-anthraquinone pulping process. A central composite design was defined in order to relate the process conditions to the composition and characteristics of the cellulose pulp. It was concluded that polynomial models encompassing linear, quadratic, and binary effect parameters reproduce the experimental results satisfactorily. Results allowed to choose high anthraquinone dosage, alkali charge and temperature, low liquid/solid ratio and short time as a compromise solution, by which the brightness, ethanol–benzene extractives content, kappa number, lignin content and viscosity were near their optimal. Low values of liquid/solid ratio reduce water consumption, which is of utmost importance in cellulose industries likewise short time treatments to save energy.
“Missing the Community for the Dots”: Newspaper Crime Maps, Territorial Stigma and Visual Criminology
Authors: Schwarze Tilman 
Published: September 2023

AbstractBy drawing on research on territorial stigmatization, critical cartography, and visual criminology, this article develops a critical literacy of crime maps to scrutinize their ability to function as adequate representations of crime. Focusing on online newspaper crime maps of homicides published by one of Chicago’s major newspapers, the Chicago Sun-Times, this article argues that crime maps assign a criminogenic character to urban spaces by spatially inscribing homicides onto community maps. In particular, this article devotes attention to the power of crime visualizations through cartography, developing strategies to educate readers about how to critically think about and read crime maps’ visualizations of the spatiality of crime. This article is intended as both a critique of crime maps’ spatio-visual practices as well as an attempt to develop a critical literacy of crime maps.
Who Identifies with the Aggregates? Philosophical Implications of the Selected Khandha Passages in the Nikāyas
Authors: Polak Grzegorz 
Published: September 2023

AbstractIn this paper, I discuss some philosophical problems connected with the notion of regarding the aggregates (khandha) as self in the Nikāyas. In particular, I focus on the attitude represented by the formula “I am this” (esohamasmi) which may be labeled as that of identifying with the aggregates. In the first part of the paper, I point out and analyze certain similes contained in the Nikāyas which may be read as implying the existence of a distinction between the aggregates and the individual who regards them as self. Then, I consider a hypothesis that the aggregates are not objective constituents of a human being but subjectively experienced representational phenomena. I argue that several Nikāya texts imply the existence of important aspects of a human being, in particular cognitive ones, which are not conceptualized in the terms of the five aggregates. I also discuss the possibility of interpreting khandhas as not active in character but as resultant of other cognitive processes. In the last part of the paper I offer a hypothesis that one of the key aspects of regarding the aggregates as self lies in the identification of a human individual with one’s own phenomenal self-representation which results in a mistaken projection of the notions of agency, identity and subjectivity onto something that is inherently devoid of it. I also consider certain parallels between the ideas present in the Nikāyas and the concepts of the modern philosophy of mind.
More insect species are supported by green roofs near public gardens
Authors: Hussain Raja Imran , Frank Thomas , Kratschmer Sophie 
Published: September 2023

AbstractRapid urbanization is among the factors that decrease insect diversity. However, by offering suitable habitats, green roofs could lessen this adverse effect. Certain factors, like a nearby public garden, could be useful predictor variables to analyze to what extent green roofs can support insect communities. The study aimed to measure the insect diversity on intensive green roofs located near public gardens and on more isolated green roofs, within an urban setting. Insect species richness, abundance, and assemblages on the green roofs near public gardens differed from those on isolated green roofs. Results indicate that green roofs near public gardens will host more species, especially pollinators, consequently lessening urbanization’s negative effect. To properly understand how landscape factors impact insect communities on green roofs, future studies on green roofs’ biodiversity should consider public gardens and their influence on urban biodiversity.Implications for insect conservationThe planning and establishment of a green roof near public gardens would probably enhance biodiversity conservation in an urban setting.