bluuebunny/crossref_metadata_2025_split huggingface dataset:
ACORDO DE ESCAZÚ E DEMOCRACIA AMBIENTAL NA GOVERNANÇA DAS ÁGUAS DO RIO MAMORÉ VERSUS EXPANSÃO ENERGÉTICA
Authors: Silva Jose Irivaldo Alves Oliveira , Nascimento Leonardo Leite , Farias Talden 
Published: September 2023

A presente proposta traz a perspectiva dos direitos de participação popular nas decisões de uso das águas do rio Mamoré, visando sua governança e segurança hídrica frente aos riscos sociais e ambientais do projeto da hidrelétrica binacional, entre Brasil e Bolívia, em estudo. Pretende-se: 1) Verificar o direito dos usos dos rios internacionais e certas decisões sobre conflitos de uso de águas transfronteiriças; 2) Avaliar a democracia ambiental na governança de águas de rios da Pan-Amazônia; e 3) Analisar como o Acordo de Escazú pode contribuir para garantir a democracia ambiental nas decisões de uso das águas do rio internacional Mamoré frente ao projeto de desenvolvimento de hidrelétrica binacional planejado no Complexo do Madeira. Para ser alcançada a conciliação entre desenvolvimento e meio ambiente na Pan-Amazônia é necessário serem limitadas as forças globais de exploração dos bens ambientais existentes, entre os quais o uso dos recursos hídricos para geração de energia elétrica.
CLINICOPATHOLOGIC VALUE OF IMMUNOHISTOCHEMICAL PINCH/LIMS-1 ANTIBODY EXPRESSION IN OVARIAN SEROUS CARCINOMA AND BORDERLINE SEROUS TUMOR
Authors: ERTUNÇ Onur , ERDEM Özlem , KAYMAK Zümrüt Arda 
Published: September 2023

Objective
Particularly interesting cys-his rich protein (PINCH/
LIMS-1), a protein implicated in cell adhesion, is
assumed to oversee the development and invasion of
cancer cells in tumors and tumor-associated stroma.
This study aimed to assess PINCH-1 expression in
serous borderline tumor (SBT) and serous carcinoma
(SC) in the tumor and peritumoral stroma and
scrutinize any associations between its expression
and various clinical and pathological parameters.
Material and Method
In this study, the expression of the PINCH-1 antibody
was analyzed in 21 cases of SBT and 89 cases of
SC using the indirect immunoperoxidase technique
with streptavidin/HRP-biotin. The staining pattern of
PINCH-1 in the tumor and peritumoral stroma was
evaluated using a semiquantitative scoring method.
The staining procedure used in the study allowed for
the accurate identification of PINCH-1 expression,
and the data obtained through the semiquantitative
scoring method provided a reliable of assessing
the degree and intensity of PINCH-1 staining. Thus,
the correlation between PINCH-1 expression and
various pathologic factors such as patient age, tumor
size, FIGO stage, intra-abdominal washing cytology,
capsule invasion, tumor location in the ovary, tumor
grade, and cancer antigen 125 (CA125) levels at the
time of diagnosis was examined.
Results
The study found that PINCH-1 was more prevalent
in cases of SC than in SBT cases. The tumors in SC
cases had stronger staining than those in SBT cases
(p
Práticas de cuidado multiprofissional durante a pandemia da COVID-19
Authors: Bezerra Nayara Kalila dos Santos , Silva Gleidilene Freitas da , Araújo Rejane Cristina de , Sousa Natália Carvalho Barbosa de , Oliveira Thalyta Ketlen de Melo , Silva Paulo Sergio da 
Published: September 2023

Objetivo: Descrever sobre as práticas de cuidado multiprofissional durante a pandemia da COVID-19. Método: Trata-se de revisão integrativa. A busca na literatura foi realizada nas seguintes bases de dados: National Library of Medicines; Base de dados bibliográficas especializada na área de Enfermagem; Literatura Latino-Americana em ciências da saúde. Foram adotados os seguintes critérios de inclusão dos materiais: artigos originais com abordagens metodológicas qualitativas, quantitativas, mistas, relatos de experiência, revisões integrativas e de escopo publicados nos anos de 2020-2021, manuscritos completos, idioma de base português brasileiro e que retrate práticas multiprofissionais de cuidar realizadas na pandemia da COVID-19. Para análise dos treze artigos selecionados foi utilizado o referencial teórico de Bardin. Resultados: Foram criadas duas categorias intituladas: Cuidados multiprofissionais envolvendo medidas de biossegurança e educação em saúde” e “Gestão do ambiente de cuidado e atendimento multiprofissional por teleconsultas”. Conclusões: As descrições sinalizam para práticas de cuidados multiprofissionais relacionadas a biossegurança dos profissionais, envolvendo o uso de equipamentos de proteção individual na prestação de cuidado seguro, lavagem das mãos, paramentação e desparamentação correta, elaboração de protocolos para enfrentamento da pandemia, gerenciamento de ambientes de cuidar, educação em saúde a partir de diálogos compartilhados entre os membros da equipe de saúde, educação permanente em saúde, capacitações para o enfrentamento da pandemia e redução de aglomerações por meio das teleconsultas.
Palavras-chave: Assistência Integral à Saúde; Infecções por coronavírus; Saúde Pública.
ДОСВІД ВИКЛАДАННЯ НАВЧАЛЬНОЇ ДИСЦИПЛІНИ БУХГАЛТЕРСЬКИЙ ОБЛІК В УМОВАХ ВОЄННОГО СТАНУ
Authors: Чук Олена 
Published: September 2023

У статті розглянуто проблеми та інноваційні підходи в сучасній освіти. Розкрито досвід викладання бухгалтерського обліку в умовах воєнного стану.
A COMPETENCY-BASED CURRICULUM AS THE BASIS FOR THE FORMATION OF FUTURE COMPETENT SPECIALISTS
Authors: Alver Jaan , Alver Lehte 
Published: September 2023

The process of globalization sets new requirements for the professional qualification of accountants and auditors. In the business world globalized investment market demands consistent high quality financial information across borders; investors are looking for a global accounting profession to provide it. Over the last two decades, academics and practitioners have questioned whether academia is keeping up with the needs of the accounting profession. There is more pressure on accounting professionals to expand and enhance their knowledge, skills, and abilities beyond what they are currently likely to possess. Providers of accounting education must take into account the changed world and create contemporary curricula. The paper gives a brief overview of competency-based approach in building up an accounting curriculum.
The relevance of financial inclusion on social problems, a causality demonstration
Authors: Vera Sánchez Fernando 
Published: September 2023

This study aims to contribute to the literature by assessing the causal relation among financial inclusion and social variables. Using Generalized Method of Moments and Directed Acyclic Graphs, on data for 92 countries for the year 2019, from the World Bank, we can prove that variables like number of automated teller machines and commercial bank branches (financial inclusion variables), have an impact on child mortality and education (social variables). This study´s limitations include the availability of data for every country, on this manner, we recommend a panel data analysis where we can incorporate time series analysis for the available data set, and other econometric techniques like Vector Autoregressive and Cointegration. To our knowledge, this is the first study to use the technique of Directed Acyclic Graphs to estimate causality in any research related with financial inclusion.
Blanqueamiento externo en dientes con discromía: una serie de casos
Authors: Melendez Diego , Solar Cesar , Delgado-Cotrina Leyla , Yileng Tay Lidia 
Published: September 2023

La discromía de piezas dentarias es un problema clínico frecuente en la práctica dental que llega a ser una preocupación estética que puede afectar a la autoestima del paciente. Aunque la técnica de blanqueamiento interno está asociada a resultados óptimos a largo plazo, existen casos en donde no es posible realizar una apertura cameral. Por lo tanto, el presente reporte de casos muestra el uso del blanqueamiento externo con las técnicas en consultorio y domiciliaria en dientes oscurecidos donde se consiguió con éxito restaurar el color natural de forma conservadora.
Managing and Reporting of Shari’ah Non-Compliant Income in Malaysian Islamic Banks: A Methodology Perspectives
Authors: Johari Norhanizah , Kasim Nawal , Ali Nor , Arshad Roshayani 
Published: September 2023

Shari’ah Compliance and Governance Framework is essential to guide the banks on the regulatory requirement as it supports the growth and development of the Islamic finance industry. Section 28(1) and Section 28(3) of the Islamic Financial Services Act (IFSA) 2013, states that IFI needs to comply with the Shari’ah principles in all of their activities religiously. Managing and reporting Shari’ah Non-Compliance (SNC) for instance, are crucial operational matters to the banks. In most cases, Islamic banks could be exposed to SNC incidents due to Shari’ah non-compliance events (SNCE) or Shari’ah Non-Compliant Income (SNCI). This study will be focusing on SNCI, unblessed income that should be de-recognized from the bank’s income. To investigate the end-to-end process of managing and reporting SNCI in Malaysian Islamic banks, the insight of the key functions, and the Shari’ah scholars were obtained. Besides in-depth interviews, documentation review of relevant policy documents, and content analysis on the annual reports of ten Islamic banks were also performed to fulfill the delineated research objectives. Besides data source and methods triangulation, ‘The Six Phases of Reflexive Thematic Analysis’ was also applied to explore and develop an understanding of patterned meaning across the datasets, eased by Atlas.ti. Finally, a guideline of best practices in managing and reporting the SNCI is proposed to Malaysian Islamic banks.

Keywords: Non-complaint income; financial reporting; disclosure; Islamic banks; triangulation
The Blinking Test (Faheem’s Approach) : A Promising Tool for Assessing Tubal Patency and Blockage
Authors: Faheem Hossam , Elswesy Abdo , Essam Reham , Ezzat Laila 
Published: September 2023

Abstract
Objective
To evaluate the specificity and sensitivity of hysteroscopic tubal patency assessment using the tubal ostium movement (blinking test).
Method
This cross-sectional study was conducted at the Aswan Specialized Hospital, Aswan. Egypt and involved 55 infertile patients in the period from Jan 2022 to Mars 2022. Participants were recruited from the outpatient population visiting the gynecological clinic at ABC Fertility Center. Those who underwent hysteroscopy were further offered laparoscopic chromopertubation to complete the assessment, all within the same setting.
Results
The blinking test showed a sensitivity of 82.50% for detecting right tubal patency and 92.31% for detecting left tubal patency, along with a specificity of 100% for both right and left tubal patency. Both the positive predictive value and negative predictive value were 100%. The overall accuracy of the blinking test was 87.27% for right tubal patency and 94.55% for left tubal patency. Furthermore, the blinking test's diagnostic value was supported by the favorable area under the curve (AUC) values, ranging from 0.87 to 0.961 in the ROC curve analysis.
Conclusion
The blinking test has shown promising results as a diagnostic method for assessing tubal patency in infertile patients. It is a useful tool for assessing tubal factor infertility because of its excellent sensitivity, specificity, positive predictive value, negative predictive value, and accuracy.
Impact of early preeclampsia prediction on medication adherence and behavior change: a survey of pregnant and recently-delivered individuals
Authors: Cowan Alison , Haverty Carrie , MacDonald Reece , Khodursky Arkady 
Published: September 2023

Abstract
Background: Behavior change and medication adherence represent potential barriers to optimal prevention of pregnancy complications including preeclampsia. We sought to evaluate baseline sentiments on pregnancy care and medication amenability, and how these measures would be impacted by early predictive testing for preeclampsia.
Methods: We developed a digital survey to query participants’ baseline sentiments on pregnancy care, knowledge about pregnancy complications, and views on a hypothetical test to predict preeclampsia. The survey was administered online to pregnant and recently-delivered individuals in the United States. Survey data were analyzed using pooled two-sample proportion z-tests with adjustment for multiple comparisons.
Results: 1022 people completed the survey. 84% reported they were satisfied with their pregnancy care. Self-assessed knowledge about preeclampsia was high, with 75% of respondents reporting they have a “good understanding” of preeclampsia, but measured knowledge was low, with only 10% able to identify five common signs/symptoms of preeclampsia. 91% of participants desired early pregnancy predictive testing for preeclampsia. 88% reported they would be more motivated to follow their provider’s medication recommendations and 94% reported they would desire home blood pressure monitoring if found to be at high risk for preeclampsia. Increased motivation to follow clinicians’ medication and monitoring recommendations was observed across the full spectrum of medication amenability. Individuals who are more medication-hesitant still reported high rates of motivation to change behavior and adhere to medication recommendations if predictive testing showed a high risk of preeclampsia.
Conclusion: While satisfaction with care is high, participants desire more information about their pregnancy health, would value predictive testing for preeclampsia, and report they would act on this information. Participants across the spectrum of medication amenability reported that they would be more likely to adhere to medication and behavioral changes if they had an early predictive test for preeclampsia.
Uptake of hepatitis B treatment eligibility tests among hepatitis B patients; The case of Yumbe regional referral hospital, Uganda
Authors: Mutaryebwa Felix , Mutyoba Joan Nakya , Ssekamatte Tonny , Frances Acheng , Jerry Aleku , Nasur Mubarak , Naziru Rashid 
Published: September 2023

Abstract
Background:Despite hepatitis B virus infection being a vaccine preventable liver disease, 257 million people are estimated to be chronically infected globally making it one of the commonest infections, causing more than 820,000 deaths annually worldwide. Uganda is one of the SSA that continues to be highly endemic with a prevalence of 4.3%, associated with poor clinical management of those infected.
Objectives:Assess factors associated with uptake of recommended HBV treatment eligibility tests among HBV patients at YRRH.
Methods: Data was collected using both quantitative and qualitative approaches. Chi square and modified Poisson regression analyses were undertaken to determine association of factors. 01 FGD and 04 KI interviews were conducted to explore factors affecting the provision of recommended hepatitis B treatment eligibility tests. Data was analyzed using inductive thematic analysis.
Results. 1.01% patients took all 4 tests and 26.6% received at least one test. CBC was mostly consumed, 38.2% while USS was the least -7%, 7.5% patients were screened for HIV with 33.3% being HIV/HBV coinfected. 61.3% patients did not take any main test and 31.2% had a main test taken. Only 7.5% had both main tests. Uptake of main tests was associated with timing of tests (χ2 = 94.9, P< 0.000), HIV/HBV coinfection (χ2 = 20.46, P<0.000), duration in care, (χ2=68.9, P<0.000), average distance to hospital (χ2 = 15.5, P<0.017). Timing of tests was the only factor statistically associated with uptake of main recommended tests (PR = 0.44, 95% CI 0.210 – 0.92). Facilitators for provision of HBV tests included availability of commodities, HCWs’ knowledge of the treatment guidelines and good infrastructure while barriers were insufficient human resource, commodity stock outs and language barrier.
Conclusion. There was poor uptake of recommended tests by HBV patients at YRRH. HCWs should endeavor to provide all recommended tests before HBV treatment initiation.
Husband's Participation in Family Planning Program through Post Placental IUD in Malang Regency: A Qualitative Study
Authors: Sulistiyanto Henri , Soetrisno Soetrisno , Subijanto A.A , Setyowati Retno 
Published: September 2023

Abstract
From the method's selection to its application, the main issue with the application of contraceptives tends to be directed at women, and if there is a risk, the woman becomes the one who has to endure it. On the other side, the low coverage of family planning, particularly in postpartum, is a result of inadequate knowledge, a lack of information and counseling, and an absence of support from the husband. Health education, especially family planning, is more aimed at pregnant women, but in reality the culture of society in Indonesia adheres to a patriarchal culture. The patriarchal culture's emphasis on the husband's role as the decision-maker made it challenging to convince spouses regarding the roles of contraception, particularly Post-Placental IUD. This study aims to investigate how the husband influences pregnant women's preference for Post-Placental IUD contraception in Malang Regency. The research method used is "research that produces descriptive data from people and observed behaviour and in the form of written and oral. This study is considered as a qualitative research with a phenomenological approach. The informants in this study were husbands and pregnant women, health centre midwives, coordinating midwives, and persons in charge of the family planning program at the Health Office of Malang Regency. This research was conducted in July-December 2022. Data collection was performed by interview. The results in this study concluded that the low participation of husband in Post Placental IUD is due to husband's inadequate knowledge as well as lack of information and counselling. Therefore, it is hoped that health workers could provide counselling and home visits to families especially to husbands.
Redox Dynamics and Surface Structures of an Active Palladium Catalyst during Methane Oxidation
Authors: Huang Xing , Yue Shengnan , Praveen C. , Klyushin Alexander , Hashimoto Masahiro , Li Qian , Jones Travis , Liu Panpan , Yu Wenqian , Willinger Marc 
Published: September 2023

Abstract

Catalysts based on palladium are among the most effective in the complete oxidation of methane. Despite extensive studies, the nature of their catalytically active species and conceivable structural dynamics remains elusive. Here, we combine operando transmission electron microscopy (TEM) with near-ambient pressure X-ray photoelectron spectroscopy (NAP-XPS) and density functional theory (DFT) calculations to investigate the active state and catalytic function of Pd nanoparticles (NPs) under methane oxidation conditions. By direct imaging we show how the particle size, phase composition and dynamics respond to changes of the gas-phase chemical potential and how Pd catalysts transform from a static state to a highly dynamic, catalytically active state that is characterized by phase coexistence and oscillatory phase transition in a reactive atmosphere. Aided by DFT calculations, we rationalize the origin for the observed redox dynamics and provide atomistic insights into the active structures and the underlying reaction mechanism.
Association of Serum Albumin with Heart Failure Mortality with NYHA Class IV in Chinese Patients: Insights from PhysioNet Database
Authors: Chen Yun , Cai Xian-bin , Yao Xin , Zhang Shao-hui , Cai Min-hua , Li Hao-peng , Jing Xu-bin , Zhang Yong-gang , Ding Qia-feng 
Published: September 2023

Abstract
Aims
Studies have proved that low albumin level is associated with increased mortality in most diseases, such as chronic kidney disease and hepatic cirrhosis. However, the relationship between albumin and all-cause death in heart failure patients in China is still unclear. We aimed to investigate the association between albumin levels and 28-day mortality in Chinese hospitalized patients with NYHA IV heart failure.
Methods
A total of 2008 Chinese patients were included. The correlation between serum albumin level and mortality was tested using a cox proportional hazards regression model. The smooth curve fitting was used to identify non-linear relationships between serum albumin and mortality. The Forest plot analysis was used to assess the association between albumin and 28-day mortality in different groups.
Results
Compared with patients with NYHA II-III, patients with NYHA IV had lower albumin levels and higher mortality within 28 days. The albumin on admission was independently and inversely associated with the endpoint risk, which remained significant (hazard ratio: 0.80; 95% confidence interval: 0.66 to 0.96; p = 0.0196) after multivariable adjustment. The smooth curve fitting showed with the increase of albumin, the mortality within 28 days would decrease. A subgroup analysis found that the inverse association between the albumin levels and risk of the mortality was consistent across the subgroup stratified by possible influence factors.
Conclusion
Serum albumin level is negatively associated with 28-day mortality in hospitalized heart failure patients within NYHA IV in China, which can be used as an independent predictor.
Mitigating non-genetic resistance to checkpoint inhibition based on multiple states of immune exhaustion
Authors: Kareva Irina , Gevertz Jana 
Published: September 2023

Abstract
Despite the revolutionary impact of immune checkpoint inhibition on cancer therapy, the lack of response in a subset of patients, as well as the emergence of resistance, remain significant challenges. Here we explore the theoretical consequences of the existence of multiple states of immune cell exhaustion on response to checkpoint inhibition therapy. The emerging understanding is that T cells can exist in various states: fully functioning cytotoxic cells, reversibly exhausted cells with minimal cytotoxicity, and terminally exhausted cells. We hypothesize that it is inflammation induced by drug activity that triggers transitions between these phenotypes, which can lead to non-genetic resistance to checkpoint inhibitors. We introduce a conceptual mathematical model, coupled with a standard 2-compartment pharmacometric (PK) model, that incorporates these mechanisms. Simulations of the model reveal that, within this framework, the emergence of resistance to checkpoint inhibitors can be mitigated through altering the dose and the frequency of administration. Our analysis also reveals that standard PK metrics do not correlate with treatment outcome. However, we do find that levels of inflammation that we assume trigger the transition from the reversibly to terminally exhausted states play a critical role in therapeutic outcome. A simulation of a population that has different values of this transition threshold reveals that while the standard high-dose, low-frequency dosing strategy can be an effective therapeutic design, it is likely to fail a significant fraction of the population. Conversely, a metronomic-like strategy that distributes a fixed amount of drug over many doses given close together, is predicted to be effective across the entire simulated population, even at a relatively low cumulative drug dose. Our theoretical analyses demonstrate the potential of mitigating resistance to checkpoint inhibitors via dose modulation.