bluuebunny/crossref_metadata_2025_split huggingface dataset:
Eight weeks of aerobic exercise, but not four, improves insulin sensitivity and cardiovascular performance in young women
Authors: Sellami Maha , Almuraikhy Shamma , Naja Khaled , Anwardeen Najeha , Al-Amri Hadaia Saleh , Prince Mohammad Shoaib , Aden Amina Ali , Doemling Alexander , Elrayess Mohamed A. 
Published: January 2025

Abstract
Regular aerobic exercise has a significant impact on glucose metabolism and lipid profiles, contributing to overall health improvement. However, evidence for optimal exercise duration to achieve these effects is limited. This study aims to explore the effects of 4 and 8 weeks of moderate-intensity aerobic exercise on glucose metabolism, lipid profiles, and associated metabolic changes in young female students with insulin resistance and varying body mass, seeking to determine the optimal duration for physiological adaptations. Twenty-eight physically semi-active female students were randomly assigned to 4-week (G4, n = 13, age = 23.31 ± 5.19, BMI = 24.78 ± 5.87) and 8-week (G8, n = 15, age = 21.8 ± 2.56, BMI = 24.95 ± 4.81) training groups. The aerobic intervention maintained an intensity of 40–70% of maximum heart rate (HRmax). 6-min-walk test (6MWT), handgrip strength tests, insulin, HOMA-IR, lipid profiles, and metabolic profiles were assessed pre- and post-intervention. Following the intervention, G8, but not G4, exhibited a significant decrease in HOMA-IR (-14.59%, p = 0.047). The improvement in HOMA-IR was accompanied by notable improvements in 6-MWT (+ 38.18%, p < 0.001) and handgrip strength (+ 11.62, p = 0.027 and + 17.59%, p = 0.013), and increased levels of bilirubin degradation products, ribose, and glutarate. The elevated levels of bilirubin degradation products, known for their antioxidant properties, suggested a potential antioxidative response triggered by prolonged aerobic exercise. Additionally, an increase in ribose and glutarate indicated improved metabolic flexibility and enhanced utilization of alternative energy substrates. The 8-week aerobic exercise regimen demonstrated enhanced insulin sensitivity, upper body strength, and cardiovascular performance in young females compared to a 4-week regimen by triggering specific metabolic adaptations. These findings emphasize the complex relationship between exercise duration, metabolic adaptations, and overall well-being in young women, providing valuable insights for optimizing exercise prescriptions in promoting metabolic health.
Enantioselective OTUD7B fragment discovery through chemoproteomics screening and high-throughput optimisation
Authors: Vuorinen Aini , Kennedy Cassandra R. , McPhie Katherine A. , McCarthy William , Pettinger Jonathan , Skehel J. Mark , House David , Bush Jacob T. , Rittinger Katrin 
Published: January 2025

Abstract
Deubiquitinating enzymes (DUBs) are key regulators of cellular homoeostasis, and their dysregulation is associated with several human diseases. The ovarian tumour protease (OTU) family of DUBs are biochemically well-characterised and of therapeutic interest, yet only a few tool compounds exist to study their cellular function and therapeutic potential. Here we present a chemoproteomics fragment screening platform for identifying novel DUB-specific hit matter, that combines activity-based protein profiling with high-throughput chemistry direct-to-biology optimisation to enable rapid elaboration of initial fragment hits against OTU DUBs. Applying these approaches, we identify an enantioselective covalent fragment for OTUD7B, and validate it using chemoproteomics and biochemical DUB activity assays.
Comparative Outcomes Between Three Different Techniques in the
Fixation of Ulnar Styloid Fractures
Authors: Acar Bariş , Orman Osman , Baydar Mehmet , Oruç Sevinç Ödül , Uzun Baki Avşar 
Published: January 2025

Abstract
Purpose This study aims to compare the clinical and radiological outcomes
of three different techniques used in the surgical treatment of ulnar styloid
fractures.
Material and Method Ulnar styloid fractures treated surgically between
2012 and 2022 were evaluated retrospectively. There were three groups in the
study: Group I (Kirschner wire, N= 19), Group II (tension band, N= 27) and Group
III (headless compression screw, N= 25). The Gaulke classification was applied
to categorise the fractures. After a follow-up period of at least one year,
range of motion, Modified Mayo Wrist Score (MMWS), Quick Disabilities of the
Arm, Shoulder and Hand Score (QDASH), Visual Analogue Scale (VAS) and grip
strength were measured. In addition, radiological union, bone resorption and
dorsal subluxation of the DRUJ were evaluated.
Results There was no difference between the three groups in terms of
demographic data. Gaulke type 2 A was more frequently observed in all three
groups (47.4%, 74.1%, 64%, respectively). Range of motion (flexion, extension,
supination, pronation) was similar in all three groups (p>0.05). QDASH and
MMWS were similar in all three groups. Grip strength was significantly lower in
Group I than in Group II (p=0.039). Radiological outcomes (nonunion, dorsal
subluxation, bone resorption) were similar in all three groups. Implant
irritation was significantly higher in Group II (p=0.026).
Conclusion K-wires, tension band wiring and headless compression screws
yield similar clinical and radiological outcomes in the surgical treatment of
unstable ulnar styloid fractures. However, the need for secondary surgery is
more frequent when a tension band is used. Level of Evidence: Level IV.
Recent Progress in Base-Metal-Catalyzed Dearomative Reaction of N-Heteroarenes
Authors: Ni Qian , Chen Yaqi , Ma Yuanhong 
Published: January 2025

AbstractThree-dimensional nitrogen-containing heterocyclic compounds widely exist in many natural products and drugs. The dearomatization of N-heteroarenes and their derivatives have been recognized as one of the most important and powerful strategies for the rapid and efficient synthesis of various three-dimensional nitrogen-containing heterocyclic compounds. In this short review, the recent and representative advances in base-metal-catalyzed dearomatization of N-heteroarenes are summarized and discussed.1	Introduction2	Dearomatization of Indoles2.1	Copper Catalysis2.2	Nickel Catalysis2.3	Cobalt Catalysis2.4	Other Catalysts3	Dearomatization of Pyridines, Quinolines, Isoquinolines, and Pyrazine3.1	Copper Catalysis3.2	Nickel Catalysis3.3	Cobalt Catalysis3.4	Other Catalysts4	Summary and Outlook
Personalizing Perioperative Chemotherapy in Colon Cancer
Authors: Pang Joyce H. , Baldi Charles A. , Herzig Daniel O. 
Published: January 2025

AbstractThe traditional, surgery-first approach for colon cancer is increasingly challenged by our evolving understanding of tumor biology and a growing number of measurable tumor features that can help guide contemporary treatment plans. Certain tumor characteristics now make it practical to challenge locally advanced colon cancer with neoadjuvant chemotherapy or immunotherapy, and allow for targeted postoperative therapies. The contemporary data supporting these tailored approaches to integrating systemic therapy before or after resection are summarized in this article.
Phononic Resonant Relaxation in Magnetic Hysteresis of Single-Molecule Magnets
Authors: Gu Lei , Luo Jia , Luo Qiancheng , Zhai Yuanqi , Zheng Yan-Zhen , Zhao Guoping 
Published: January 2025

Abstract
Lanthanide-based single-molecule magnets can exhibit broad magnetic hysteresis which basically manifests slow magnetic relaxation in strong magnetic fields. However, the cause of numerous nontrivial hysteresis behaviors remain debated. Here, we put forward two influential mechanisms: the activation of optical-phonon-mediated direct transitions within the ground-state doublet and resonant Raman process. These discoveries, coupled with the g-factor anisotropy, can account for observed hysteresis behaviors in the regimes of fast magnetic relaxation. Our findings substantially complement the recognized mechanisms used to interpret the magnetic hysteresis of single molecule magnets.
Position and orientation determination using quadric fitting optimization for object’s motion analyzing
Authors: Ni Yubo , Wang Xiangjun , Zhang Zonghua , Meng Zhaozong , Gao Nan 
Published: January 2025

Abstract
The accurate determination of the position and orientation of moving objects from images is a critical challenge in visual sensing, with significant implications for robotics, augmented reality and computer vision. Traditional pose estimation methods often fail in complex scenarios due to inconsistent and imprecise feature extraction. This research introduces a novel quadric fitting optimization framework that exploits the compact representation of ellipsoids for robust motion analysis. We propose Manhattan and Euclidean norm-based solvers, designed to optimize quadric fitting for varying object scales and distances. A hybrid approach is developed to strategically fuse these solvers to maximize accuracy and efficiency in various practical applications. Theoretical analysis and extensive experimental validation demonstrate the significant improvements offered by our method over conventional techniques, particularly under challenging conditions. This work not only advances the state of the art in object pose determination, but also provides a solid foundation for improved manipulation and understanding of moving objects in dynamic environments.
Engineered ionic polymer metal composites (eIPMCs) under dynamic compression loading conditions: theory and experiments
Authors: Fakharian Omid , Nagel William S , Leang Kam K , Aureli Matteo 
Published: January 2025

Abstract
Engineered Ionic Polymer Metal Composites (eIPMCs) represent the next generation of IPMCs, soft electro-chemo-mechanically coupled smart materials used as actuators and sensors. Recent studies indicate that eIPMC sensors, featuring unique microstructures at the interface between the ionic polymer membrane and the electrode, exhibit enhanced electrochemical behavior and sensitivity under compression, as compared to traditional IPMCs. However, a complete and experimentally-validated model of how eIPMCs behave under dynamic compression loads is currently missing. In this paper, we develop an analytical model for eIPMC sensors, elucidating the role of the engineered interface, modeled as a separate material layer with unique mechanical and electrochemical properties. Theoretical predictions focus on the mechanical-to-electrochemical transduction response under dynamic compressive loads. Experimental verification is conducted on conventional IPMC and novel eIPMC samples fabricated using the polymer abrading technique. Electrochemical impedance spectroscopy is performed to study the effect of the engineered interface on the electrochemical properties. Open-circuit (OC) voltage and short-circuit (SC) current are measured under external compressive loads in different loading scenarios to demonstrate sensing performance. Results show good qualitative agreement between experimental trends and model predictions. Experiments over the frequency range 1–

18

Hz

demonstrate an increase of 220%–290% in open-circuit voltage and 17%–166% in SC current sensitivity for eIPMCs over IPMCs.
Magneto-nonlinear Hall effect in time-reversal breaking system
Authors: Zhang Anwei , Rhim Jun-Won 
Published: January 2025

Abstract
Magneto-nonlinear Hall effect is known to be intrinsic and requires time-reversal symmetry. Here we show that a new type of magneto-nonlinear Hall effect can occur in the time-reversal breaking materials within the second-order response to in-plane electric and vertical magnetic fields. Such a Hall response is generated by the oscillation of the electromagnetic field and has a quantum origin arising from a geometric quantity associated with the Berry curvature and band velocity. We demonstrate that the massive Dirac model of LaAlO3/LaNiO3/LaAlO3 quantum well can be used to detect this Hall effect. Our work widens the theory of the Hall effect in the time-reversal breaking system by proposing a new kind of nonlinear electromagnetic response.
Imaging reionization's last phases with I-front Lyman-α emissions
Authors: Wilson Bayu , D'Aloisio Anson , Becker George D. , Cain Christopher , Visbal Eli 
Published: January 2025

Abstract
Long troughs observed in the z > 5.5 Lyα and Lyβ forests are thought to be
caused by the last remaining neutral patches during the end phases of reionization — termed
neutral islands. If this is true, then the longest troughs mark locations where we are most
likely to observe the reionizing intergalactic medium (IGM). A key feature of the neutral islands
is that they are bounded by ionization fronts (I-fronts) which emit Lyman series lines. In this
paper, we explore the possibility of directly imaging the outline of neutral islands with a
narrowband survey targeting Lyα. In a companion paper, we quantified the intensity of
I-front Lyα emissions during reionization and its dependence on the spectrum of incident
ionizing radiation and I-front speed. Here we apply those results to reionization simulations to
model the emissions from neutral islands. We find that neutral islands would appear as diffuse
structures that are tens of comoving Mpc across, with surface brightnesses in the range ≈ 1
- 5× 10-21 erg s-1 cm-2 arcsec-2. The islands are brighter if the
spectrum of ionizing radiation driving the I-fronts is harder, and/or if the I-fronts are moving
faster. We develop mock observations for current and futuristic observatories and find that,
while extremely challenging, detecting neutral islands is potentially within reach of an ambitious
observing program with wide-field narrowband imaging. Our results demonstrate the potentially high
impact of low-surface brightness observations for studying reionization.
Free energy equivalence between mean-field models and nonsparsely diluted mean-field models
Authors: Okuyama Manaka , Ohzeki Masayuki 
Published: January 2025

Abstract
We studied nonsparsely diluted mean-field models that differ from sparsely diluted mean-field models, such as the Viana–Bray model. When the existence probability of each edge follows a Bernoulli distribution, we rigorously prove that the free energy of nonsparsely diluted mean-field models with appropriate parameterization coincides exactly with that of the corresponding mean-field models in ferromagnetic and spin-glass models composed of any discrete spin S in the thermodynamic limit. Our results is a broad generalization of the result of a previous study (Bovier and Gayrard 1993 J. Stat. Phys.
72 643), where the densely diluted mean-field ferromagnetic Ising model (diluted Curie–Weiss model) with appropriate parameterization was analyzed rigorously, and it was proven that its free energy was exactly equivalent to that of the corresponding mean-field model (Curie–Weiss model).
SymbolNet: neural symbolic regression with adaptive dynamic pruning for compression
Authors: Tsoi Ho Fung , Loncar Vladimir , Dasu Sridhara , Harris Philip 
Published: January 2025

Abstract
Compact symbolic expressions have been shown to be more efficient than neural network (NN) models in terms of resource consumption and inference speed when implemented on custom hardware such as field-programmable gate arrays (FPGAs), while maintaining comparable accuracy (Tsoi et al 2024 EPJ Web Conf.
295 09036). These capabilities are highly valuable in environments with stringent computational resource constraints, such as high-energy physics experiments at the CERN Large Hadron Collider. However, finding compact expressions for high-dimensional datasets remains challenging due to the inherent limitations of genetic programming (GP), the search algorithm of most symbolic regression (SR) methods. Contrary to GP, the NN approach to SR offers scalability to high-dimensional inputs and leverages gradient methods for faster equation searching. Common ways of constraining expression complexity often involve multistage pruning with fine-tuning, which can result in significant performance loss. In this work, we propose

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y
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, a NN approach to SR specifically designed as a model compression technique, aimed at enabling low-latency inference for high-dimensional inputs on custom hardware such as FPGAs. This framework allows dynamic pruning of model weights, input features, and mathematical operators in a single training process, where both training loss and expression complexity are optimized simultaneously. We introduce a sparsity regularization term for each pruning type, which can adaptively adjust its strength, leading to convergence at a target sparsity ratio. Unlike most existing SR methods that struggle with datasets containing more than

O

(
10
)

inputs, we demonstrate the effectiveness of our model on the LHC jet tagging task (16 inputs), MNIST (784 inputs), and SVHN (3072 inputs).
1968
Authors: Palomares-Salas Claudio 
Published: January 2025

Abstract
Chapter 4 marks Canto Nuevo’s birth during the 1968 student movement. It explores the emergence of a repertoire of national militant songs focused on the Mexican context but in tune with the Latin American Militant Song movement. Following Jorge Velasco’s previous studies, the chapter explores three ways in which singers, singer-songwriters, and groups used songs during the student movement: first, by collecting popular militant songs; second, by resignifying these songs using the contrafacta; and third, by creating an original militant song repertoire. At this moment, the first Canto Nuevo generation arose. It included Judith Reyes, José de Molina, León Chávez Teixeiro, Óscar Chávez, the group Los Nakos, Margarita Bauche, and Enrique Ballesté. The chapter thoroughly explores their works.
Peak and Decline (1982–1989)
Authors: Palomares-Salas Claudio 
Published: January 2025

Abstract
Chapter 7 explores the peak and decline of Canto Nuevo in the years 1982–1989. It discusses important Nueva Canción festivals held in Mexico City (1982), Managua (1983), Quito (1984) and Lima (1986), and the emergence of the Comité Internacional de la Nueva Canción and the Comité Mexicano de la Nueva Canción. It explores the appearance of the Rupestre movement and the so-called Mexican Trova, which exemplify the depoliticization processes occurring in the 1980s. It then discusses the 1985 earthquake, the OTI festival, and the creation of the Canto Nuevo series by RCA Victor, which prelude the movement’s decline. Finally, it discusses the 1988 controversial presidential election and how the fall of the Berlin Wall and the ensuing downfall of the Soviet Union marked the end of Canto Nuevo’s more relevant period in the country’s cultural history, as the Marxist/humanist structures that sustained it since the 1960s collapsed.
Is access to crisis teams associated with changes in behavioral health mortality?
Authors: Newton Helen , Beetham Tamara , Busch Susan H 
Published: January 2025

Abstract
Behavioral health–related mortality—deaths from suicide, drug overdose, and acute alcohol injury—are leading causes of death among US adults. Crisis teams, trained behavioral health professionals who serve as first responders to assess and stabilize clients in crisis, as well as refer to treatment as necessary, have been shown to reduce psychiatric hospitalizations, but whether crisis teams reduce behavioral health mortality has not been studied. We assessed the association between changes in access to crisis team programs and changes in county-level suicide, drug overdose, and acute alcohol injury mortality from 2014 through 2019. We found that 250 (9%) of counties experienced crisis team program entry and another 237 (9%) experienced crisis team program closure. Access to crisis team programs was associated with significant changes in county-level drug overdose deaths, but not suicide or acute alcohol injury. Compared with counties with no change in access, crisis team program entry was associated with a 7% reduction in county-level drug overdose death rates, and crisis team program closure was associated with a 13% increase in drug overdose death rates. These findings may support the use of crisis teams as 1 intervention to address substance use disorder treatment gaps in the United States.
Chromosome-scale and haplotype-resolved genome assembly of Populus trichocarpa
Authors: Gao Wentao , Wang Sui , Jiang Tao , Hu Heng , Gao Runtian , Zhou Murong , Wang Guohua 
Published: January 2025

Abstract
Populus trichocarpa, a pivotal model organism for woody transgenic research, not only garners substantial scientific interest but plays an integral role in forestry economics. Previous genomic assemblies of P. trichocarpa predominantly treated its heterozygous genome as homozygous, thereby neglecting crucial haplotypic diversity. Leveraging the high fidelity (HiFi) sequencing capabilities of PacBio sequencing and the chromosome conformation capture insights provided by Illumina's Hi-C technique, this study is the first to achieve a near telomere-to-telomere assembly of both paternal and maternal haplotypes in P. trichocarpa. Comparative genomic analysis between these haplotypes has uncovered several allelic variants and pathways critical for trait determination through allele-specific expression. Furthermore, utilizing RNA-seq data from multiple tissues, this investigation has detailed the tissue-specific expression patterns of the leucine-rich repeat (LRR) gene family, which are essential in mediating plant signal transduction and developmental regulation. Our results not only illuminate the functional genomics landscape of P. trichocarpa but also provide invaluable theoretical underpinnings for the genetic improvement of woody plants and a robust framework for exploring genetic variability and allelic expression disparities in arboreal species.
Quality parameters and shelf life of strawberry (cv. Centenary) fruits as affected by active modified atmosphere packaging
Authors: Mulla Mehraj Fatema Z , Shonte Tigist , Pathania Shivani 
Published: January 2025

Abstract
Modified Atmosphere Packaging (MAP) has gained attention from commercial horticulturalists, in extending the shelf life of bulk and retail packaged fresh produce such as strawberries. Storing strawberries in an atmosphere with optimized gas composition containing carbon dioxide concentration from 15 to 30% and the oxygen concentration from 7.5 to 10% can provide an optimized condition to maintain quality and extend shelf life of strawberries at low temperatures. Therefore this study aimed to investigate the effect of active MAP, three different gas mixes namely: MAP1 (10 O2, 15% CO2, 75% N2); MAP2 (7.5 O2, 17.5% CO2, 75%.N2); MAP3 (30% CO2, 70%.N2) and Passive MAP as a control conventional packaging on changes in gas composition, total soluble solid, colour, electrolyte leakage and density of fresh strawberries during 15 days storage period at 4 °C and 99.9% RH. Strawberries packaged in commercial packaging PET (Polyethylene terephthalate) punnet and PET lidding with macro perforated, a mix of three 8 mm diameter hole with four 5 mm x 15 mm rectangular holes on PET lidding film under normal atmosphere was studied as a control sample. Freshly harvested strawberries were packaged in a PET punnet with PET/PE (Polyethylene terephthalate/Polyethylene) as lidding film using an automatic tray sealer. The packaged strawberries were stored at 4 °C. Storage studies revealed that significantly higher CO2 and negligible O2 concentration in MAP3 compared to the control packaging system. Greater electrolyte leakage was observed for the treatment with higher (30%) CO2 and commercial packaged sample with higher O2 concentration on 13th day of storage (P &lt; 0.05). No significant difference in density value was observed for all the treatments. L* value showed a decreasing trend in strawberries stored in commercial package with higher O2 concentration for 13 days, while it was well maintained in the MAP2 and MAP1 treatments containing 7.5 and 10% O2 up to 15 days.