bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pattern of macronutrients intake among type-2 diabetes mellitus (T2DM) patients in Malaysia
Authors: Md Isa Zaleha , Ismail Noor Hassim , Mohd Tamil Azmi , Jaafar Mohd Hasni , Ismail Rosnah , Mohamed Noor Khan Nor Ashikin , Mat Nasir Nafiza , Ab Razak Nurul Hafiza , Zainol Abidin Najihah , Yusof Khairul Hazdi 
Published: January 2023

Abstract
Background
The incidence of type 2 diabetes mellitus (T2DM) is rising rapidly in Malaysia. Modifying dietary intake is key to both the prevention and treatment of T2DM. This study aims to investigate the pattern of macronutrient intake among T2DM patients in Malaysia.

Methods
This study was carried out on adults aged between 35 and 70 years, residing in urban and rural Malaysian communities. A series of standardised questionnaires was used to assess the sociodemographic information, dietary intake and physical activity level of 15,353 respondents who provided informed consent to participate in this study. Blood sampling (finger prick test) and physical examination were performed to obtain blood glucose and anthropometric data, respectively. The Chi-square test was used to assess differences in the trends of macronutrient intake among T2DM patients.

Results
The total number of participants diagnosed with T2DM in this study was 2254. Of these, 453 (20.1%) were newly diagnosed, 1156 (51.3%) were diagnosed for ≤5 years and 645 (28.6%) were diagnosed for > 5 years. Male patients show that there were significant differences among the three groups of T2DM according to the following variables: age, BMI, residency, participant comorbidity of hypertension, family history of T2DM and hypertension, and active smoker. Meanwhile, female patients show significant differences among the three groups of T2DM according to the following variables: age, BMI, marital status, education level, residency, participant comorbidity of hypertension and family history of T2DM. Most of the male patients consumed appropriate proportions of carbohydrate (458, 60.7%) and protein (618, 81.9%). However, female patients did not show any significant differences of the macronutrients intake among the three groups of T2DM patients.

Conclusions
The pattern of dietary intake among T2DM patients in this study showed consumption of carbohydrate and protein within the range of Malaysian RNI, coupled with high fat intake. Compliance with the Recommended Nutrient Intake (RNI) was satisfactory for both carbohydrate and protein but not for fat. The pattern indicated a preference for fat rather than protein when carbohydrate intake was restricted.
Prediction of end-dialysis serum sodium concentration in severely hyponatremic kidney failure patients undergoing conventional hemodialysis using sodium kinetic equation
Authors: Gharib Mohamed Sary 
Published: January 2023

Abstract
Background and Objectives
Conventional hemodialysis (HD) for kidney failure patients with severe hyponatremia may be complicated by rapid correction of hyponatremia, which increases the risk of osmotic demyelination syndrome. A simple sodium kinetic equation was effective in prediction of end-dialysis serum Na+ in severely hyponatremic kidney failure patient treated with continuous venovenous hemofiltration, but was not tested in conventional HD. The aim of this study was to assess the validity of this equation when used in conventional HD.

Methods
Twenty conventional HD sessions were delivered to 12 kidney failure patients with severe hyponatremia (serum Na+  < 120 mEq/L). The target change in serum Na+ was 4 mEq/L. The DNa.t/V that obtained this change was predetermined according to the sodium kinetic equation and monitored in real time by online clearance monitoring software embedded in dialysis machine. The dialysis session was terminated once the target DNa.t/V was achieved.

Results
The mean observed and predicted serum Na+ were 119.80 ± 3.42 mEq/L and 119.45 ± 3.12 mEq/L, respectively. Bland–Altman plot analysis revealed a mean difference ± SD of 0.33 ± 1.26 mEq/L, and 95% limits of agreement of − 2.13 to 2.83. The imprecision in prediction of end-dialysis serum Na+ was 2.52 mEq/L. The small difference and clinically insignificant 95% limits of agreement indicate a good agreement between the observed and predicted serum Na+.

Conclusion
The sodium kinetic equation was effective in prediction of end-dialysis serum Na+ in kidney failure patients with severe hyponatremia.
A novel method for predicting hepatocellular carcinoma response to chemoembolization using an intraprocedural CT hepatic arteriography-based enhancement mapping: a proof-of-concept analysis
Authors: Taiji Ryosuke , Lin Yuan-Mao , Chintalapani Gouthami , Lin Ethan Y. , Huang Steven Y. , Mahvash Armeen , Avritscher Rony , Liu Chien-An , Lee Rheun-Chuan , Resende Vivian , Nishiofuku Hideyuki , Tanaka Toshihiro , Kichikawa Kimihiko , Klotz Ernst , Gupta Sanjay , Odisio Bruno C. 
Published: January 2023

Abstract
Background
To evaluate the feasibility of a novel approach for predicting hepatocellular carcinoma (HCC) response to drug-eluting beads transarterial chemoembolization (DEB-TACE) using computed tomography hepatic arteriography enhancement mapping (CTHA-EM) method.

Methods
This three-institution retrospective study included 29 patients with 46 HCCs treated with DEB-TACE between 2017 and 2020. Pre- and posttreatment CTHA-EM images were generated using a prototype deformable registration and subtraction software. Relative tumor enhancement (TPost/pre-RE) defined as the ratio of tumor enhancement to normal liver tissue was calculated to categorize tumor response as residual (TPost-RE > 1) versus non-residual (TPost-RE ≤ 1) enhancement, which was blinded compared to the response assessment on first follow-up imaging using modified RECIST criteria. Additionally, for tumors with residual enhancement, CTHA-EM was evaluated to identify its potential feeding arteries.

Results
CTHA-EM showed residual enhancement in 18/46 (39.1%) and non-residual enhancement in 28/46 (60.9%) HCCs, with significant differences on TPost-RE (3.05 ± 2.4 versus 0.48 ± 0.23, respectively; p < 0.001). The first follow-up imaging showed non-complete response (partial response or stable disease) in 19/46 (41.3%) and complete response in 27/46 (58.7%) HCCs. CTHA-EM had a response prediction sensitivity of 94.7% (95% CI, 74.0–99.9) and specificity of 100% (95% CI, 87.2–100). Feeding arteries to the residual enhancement areas were demonstrated in all 18 HCCs (20 arteries where DEB-TACE was delivered, 2 newly developed collaterals following DEB-TACE).

Conclusion
CTHA-EM method was highly accurate in predicting initial HCC response to DEB-TACE and identifying feeding arteries to the areas of residual arterial enhancement.
Using the free listing technique to study consumers’ representations of traditional gastronomy in Argentina
Authors: Cuffia Facundo , Rojas-Rivas Edgar , Urbine Ayelen , Zaragoza-Alonso Jazmin 
Published: January 2023

AbstractThe aims of this research were (i) to study with a sample of Argentine consumers the representations of traditional gastronomy through the free listing method; (ii) to identify consumers’ typologies according to their representation of traditional gastronomy; and (iii) to establish some methodological implications using the free listing in the study of the gastronomic field. A survey was conducted in which 249 Argentines from the Littoral area were recruited. Through a free listing task, participants were asked to mention the main foods or dishes of Argentina’s gastronomy. Twenty-eight foods, dishes or food categories were obtained that are part of the representations of Argentina’s gastronomy. The results showed a strong connection between gastronomy and the representations of the consumers with the “Asado” (CSI = 0.289, Smith = 0.613), the traditional and characteristic food of Argentine gastronomy. Three groups of consumers were identified, presenting differences in the representation of traditional gastronomy (p < 0.05). This work is pioneering for studying gastronomy representations from the consumers’ language through the free listing method using the case of traditional Argentine gastronomy. Future directions of free listing in the gastronomic field are identified and discussed.
The effect of military spending on economic growth in MENA: evidence from method of moments quantile regression
Authors: Raifu Isiaka Akande , Aminu Alarudeen 
Published: January 2023

Abstract
This study adopted a novel quantile regression via moments to explore the effects of military spending on the distribution of economic growth of 14 MENA countries over the period from 1981 to 2019. The method, apart from enabling us to investigate the effects of military spending on the distribution of economic growth at different quantiles, also helps to address issues of heterogeneity and endogeneity characterising the panel studies. Our results showed that irrespective of measures of military spending and economic growth, an upsurge in military spending leads to a positive effect on economic growth at different quantiles, suggesting that military spending is productive and growth-enhancing in the MENA countries.
Non-neoplastic disorders in an aging gut: concise review
Authors: Dawra Saurabh , Behl Pradeep , Srivastava Sharad , Manrai Manish , Chandra Alok , Kumar Anupam , Kumar Ankit , Tevatia Manveer Singh 
Published: January 2023

AbstractThe spectrum of gastrointestinal (GI) issues in the older population varies from common physiological age-related changes to devastating, less common sinister pathological illness. GI system has direct exposure to external environment. Thus, it is modeled to embrace the pathophysiological changes that occur due to interaction with external factors. Gastrointestinal tract (GIT) per se is more resilient to aging as compared to other organ systems. On the other hand, elderly may present with a large plethora of GI symptoms. This presents a challenge to all echelons of medical consultation for accurate attribution for the aging process or pathophysiological causation of GI symptoms. This dichotomy leads to hindrance in adequate and appropriate treatment of GI ailments. In GI system, non-neoplastic disorders are far more common than neoplastic disorders. Hence, it becomes imperative to understand the aging evolution of the GI system and management of GI disorders in the older population.
Assessment of vascular endothelial growth factor a serum level in pediatric hemophilic arthropathy
Authors: Saboony Omar Ahmed M. N. , Sebaie Mona Abdullah El , Mikkawy Dalia Mohamed Ezz El Din El , Ragab Iman Ahmed Mohamed , Labib Hossam Salaheldin Abdelmohsen 
Published: January 2023

Abstract
Background
Children with hemophilia have serious, recurrent joint bleeding that causes disabilities. Regular factor VIII concentrate replacements have not yet completely stopped intra-articular subclinical hemorrhages and permanent joint damage. The prevention of joint damage requires the early detection and management of this hemorrhage. Neoangiogenesis is crucial in the development of synovitis after recurrent hemophilic joint bleeding. This study assessed the level of serum Vascular endothelial growth factor A (VEGF-A) as a vascular biomarker in children with hemophilia A to determine its possible role as a diagnostic biomarker for hemophilic arthropathy.

Result
A case–control study with 30 male children who had hemophilia A and 30 healthy controls was conducted. Patients had significantly higher serum VEGF-A levels than the control group (specificity was 70.0% and sensitivity was 83.3%). Hemophilia severity and Hemophilia Joint Health Score had a significant positive correlation with VEGF-A.

Conclusion
Children with hemophilia A had significantly higher levels of VEGF-A in their serum. Additionally, VEGF-A had a significant positive correlation with Hemophilia Joint Health Score as well as the severity of the disease. In children with hemophilia A, VEGF-A can be used as a marker for early hemophilic arthropathy detection.
Migrant-Native Disparities in Obstetric Neuraxial Analgesia Use: The Role of Host-Country Language Proficiency
Authors: Hamwi Sousan , Barros Henrique , Lorthe Elsa 
Published: January 2023

BACKGROUND:
Neuraxial analgesia (NA) is the most effective modality in managing labor pain with widespread availability in high-income countries. Previous research has reported a differential obstetric NA use among migrant and native women, but the contribution of language barriers is not well understood. We aimed to investigate whether host-country language proficiency among migrant women influences NA use and satisfaction with pain management during labor, when compared to natives.

METHODS:
We conducted a secondary analysis of data collected from 1024 native and 1111 migrant women who had singleton vaginal deliveries between 2017 and 2019 and were enrolled in the nationwide Portuguese baMBINO prospective cohort study. Obstetric NA use, satisfaction with labor pain management, and migrants’ Portuguese language proficiency were self-reported. Data were analyzed using robust multilevel Poisson regression, adjusted for maternal region of birth (characterized by the Human Development Index), age, and education.

RESULTS:
Overall, 84.4% of native women gave birth with NA, compared to 81.6%, 71.3%, and 56.9% of migrant women with full, intermediate, and limited language proficiency, respectively. Compared to native women, migrants with intermediate (adjusted risk ratio [aRR] = 0.91 [95% confidence interval {CI}, 0.82–0.99]) and limited (aRR = 0.73 [95% CI, 0.56–0.94]) proficiency were less likely to receive NA. However, no significant differences were observed in pain management satisfaction by language proficiency level.

CONCLUSIONS:
Compared to native women, we observed a differential obstetric NA use across migrant women with different host-country language proficiency levels in Portugal, without affecting satisfaction with labor pain management. Although defining the mechanisms underlying NA use discrepancies requires further research, our findings support systematically evaluating pregnant migrant women’s linguistic skills and ensuring their access to adequate obstetric analgesia-related information and interpretation services.
Germ granules in development
Authors: Thomas Laura , Putnam Andrea , Folkmann Andrew 
Published: January 2023

ABSTRACT
A hallmark of all germ cells is the presence of germ granules: assemblies of proteins and RNA that lack a delineating membrane and are proposed to form via condensation. Germ granules across organisms share several conserved components, including factors required for germ cell fate determination and maintenance, and are thought to be linked to germ cell development. The molecular functions of germ granules, however, remain incompletely understood. In this Development at a Glance article, we survey germ granules across organisms and developmental stages, and highlight emerging themes regarding granule regulation, dynamics and proposed functions.
Polarization sensitivity and decentralized visual processing in an animal with a distributed visual system
Authors: Chappell Daniel R. , Speiser Daniel I. 
Published: January 2023

ABSTRACT
The marine mollusc Acanthopleura granulata (Mollusca; Polyplacophora) has a distributed visual array composed of hundreds of small image-forming eyes embedded within its eight dorsal shell plates. As in other animals with distributed visual systems, we still have a poor understanding of the visual capabilities of A. granulata and we have yet to learn where and how it processes visual information. Using behavioral trials involving isoluminant looming visual stimuli, we found that A. granulata demonstrates spatial vision with an angular resolution of 6 deg. We also found that A. granulata responds to looming stimuli defined by contrasting angles of linear polarization. To learn where and how A. granulata processes visual information, we traced optic nerves using fluorescent lipophilic dyes. We found that the optic nerves innervate the underlying lateral neuropil, a neural tissue layer that circumnavigates the body. Adjacent optic nerves innervate the lateral neuropil with highly overlapping arborizations, suggesting it is the site of an integrated visuotopic map. Using immunohistochemistry, we found that the lateral neuropil of A. granulata is subdivided into two separate layers. In comparison, we found that a chiton with eyespots (Chiton tuberculatus) and two eyeless chitons (Ischnochiton papillosus and Chaetopleura apiculata) have lateral neuropil that is a singular circular layer without subdivision, findings consistent with previous work on chiton neuroanatomy. Overall, our results suggest that A. granulata effectuates its visually mediated behaviors using a unique processing scheme: it extracts spatial and polarization information using a distributed visual system, and then integrates and processes that information using decentralized neural circuits.
Epaxial and hypaxial co-contraction: a mechanism for modulating strike pressure and accuracy during suction feeding in channel catfish
Authors: Jimenez Yordano E. , Parsons Jake W. , Brainerd Elizabeth L. 
Published: January 2023

ABSTRACTMost fish species use concentric epaxial and hypaxial contractions to suction feed, whereby both muscle groups produce cranial expansion and negative intraoral pressures. In contrast, channel catfish (Ictalurus punctatus) suction feed with little to no cranial elevation and epaxial shortening, generating suction power primarily with hypaxial shortening and pectoral girdle retraction. We hypothesized that channel catfish (1) actively anchor the head via isometric contraction of the epaxials and (2) vary feeding performance by modulating the absolute and relative outputs of the co-contracting muscles. We used a combination of electromyography, intraoral pressure recordings and specimen manipulation, and developed a new dual-lever model to explore this idea. We detected epaxial and hypaxial co-contraction prior to suction force development in all strikes. Our model revealed that the differential between the co-contracting muscles may be used to modulate suction pressure and strike accuracy.
Investigating the influence of artificial intelligence on quality management in healthcare centers
Authors: AlJarallah Nasser Ali 
Published: January 2023

Background: New emerging technologies enable healthcare centers to enhance their information technology (IT) infrastructure, which offers an opportunity to provide adequate services to patients. In Saudi Arabia, the government has initiated artificial intelligence-based technologies to increase productivity in organizations. However, recent studies demand innovative approaches for quality management in healthcare centers. In addition, there is a scarcity of techniques for evaluating the performance of healthcare professionals. Methods: The study intended to investigate the role of IT in quality management in Saudi Arabian healthcare centers. A set of hypotheses were proposed to identify the relationship between IT and quality management. A web-based questionnaire was used and interviews were conducted in the healthcare centers of Riyadh and Eastern provinces. A total of 233 healthcare professionals and management employees participated in the survey. A mixed-method approach was applied to evaluate the responses. Furthermore, exploratory and confirmatory factor analyses were used to draw insights from the data. Results: The outcome reveals a positive relationship between IT and quality management. Moreover, the thematic findings outline the importance of IT competence in healthcare centers. Conclusions: The study's findings can support healthcare centers to deploy valuable tools and techniques to improve the quality of service.
Nieznana chorągiew procesyjna z dziedzictwa kongregacji chełmińskiej w zbiorach Muzeum Diecezjalnego w Toruniu
Authors: Raczkowski Juliusz , Bucław Katarzyna 
Published: January 2023

W zbiorach Muzeum Diecezjalnego w Toruniu (MDT) znajduje się rzadki parament z XVII wieku – dwustronnie malowana (olej na płótnie) i na awersie haftowana (nici jedwabne i złote na kanwie płóciennej) chorągiew procesyjna, ukazująca świętą z zakonu benedyktynek (św. Gertrudę lub Scholastykę) i św. Biskupa (Wojciecha?). Obiekt zachował się w stanie destruktu, a jego dokładna proweniencja ani dzieje nie są znane. Na podstawie ikonografii oraz cech rękodzieła, mających analogie w innych nowożytnych haftowanych tekstyliach z regionu, można z dużym prawdopodobieństwem zakładać, że jest to element spuścizny po benedyktynkach kongregacji chełmińskiej, prawdopodobnie z Torunia. Artykuł referuje wyniki badań (ikonograficznych, zabytkoznawczych technologicznych – IR, UV, XRF), jakim poddano zabytek przy okazji przygotowania go na ekspozycję na wystawie czasowej „Diocesis nostrae patroni. Wspólne dziedzictwo diecezji chełmińskiej i toruńskiej” w MDT w 2022 roku i później, podczas trwania wystawy. Autorzy podkreślają jego unikatowy walor w zakresie funkcji i historyczną wartość jako dziedzictwa pokasacyjnego. Zwracają także uwagę na poważne związane z nim wyzwanie konserwatorsko-ekspozycyjne, którego podjęcie mogłoby wywołać szereg dylematów, ale i przynieść nowe rozwiązania dla praktyki konserwacji zabytkowych tekstyliów oraz zagadnień w dziedzinie projektowania ekspozycji muzealnej.
Product Design Enhancement for Fashion Retailing
Authors: Wang Yiwei , Choudhary Vidyanand , Yin Shuya 
Published: January 2023

As the fashion industry increasingly embraces artificial intelligence (AI), we investigate how a fast-fashion retailer should choose between using a manual design strategy or an AI-assisted design strategy to enhance existing products. A manual design is a traditional and basic approach that involves human designers only, whereas an AI-assisted design is a more innovative approach that involves both human designers and AI technologies. In this paper, the overall product enhancement is measured by two key attributes: product quality and product trendiness. Product quality can be measured by the product’s longevity as reflected by the quality of the materials and types of fabric and stitching used, where the product’s improvement level can be determined by the retailer in a continuous range. Consequently, the retailer may choose different levels of product quality under different design strategies. The two design approaches also lead to different natures of product trendiness, which is reflected by features such as styles, new materials, and colors, to name just a few. Specifically, we assume that the traditional manual design can predict well how trendy or popular the new product is. Hence, the trendiness attribute under the manual design is deterministic. However, given the uncertain nature of the AI-assisted design technology and the needed coordination between human designers and the adopted technologies, the trendiness of the new product designed under the AI-assisted approach is assumed uncertain. Two sets of designing costs are considered in product enhancement: the fixed design cost that is irrespective of the production volume and the variable marginal cost. Our analysis of the base model highlights the importance of decomposing different costs in determining the optimal design strategy. Specifically, the manual design is preferred when the fixed cost carries more weight, whereas the AI-assisted design is preferred when the marginal cost is a more important factor. Moreover, a higher level of innovation uncertainty under the AI-assisted design gives this strategy an advantage over the manual design. In our extended models, we demonstrate that (1) these results are robust even if the retailer does not have the flexibility to offer the existing product when the AI-assisted design is unpopular, and (2) the relative position of human designers in the two design approaches has an impact on the effects of these costs. Supplemental Material: The online appendix is available at https://doi.org/10.1287/serv.2023.0315 .