bluuebunny/crossref_metadata_2025_split huggingface dataset:
BCL11B and the NuRD complex cooperatively guard T‐cell fate and inhibit OPA1‐mediated mitochondrial fusion in T cells
Authors: Liao Rui , Wu Yi , Qin Le , Jiang Zhiwu , Gou Shixue , Zhou Linfu , Hong Qilan , Li Yao , Shi Jingxuan , Yao Yao , Lai Liangxue , Li Yangqiu , Liu Pentao , Thiery Jean Paul , Qin Dajiang , Graf Thomas , Liu Xingguo , Li Peng 
Published: September 2023

AbstractThe nucleosome remodeling and histone deacetylase (NuRD) complex physically associates with BCL11B to regulate murine T‐cell development. However, the function of NuRD complex in mature T cells remains unclear. Here, we characterize the fate and metabolism of human T cells in which key subunits of the NuRD complex or BCL11B are ablated. BCL11B and the NuRD complex bind to each other and repress natural killer (NK)‐cell fate in T cells. In addition, T cells upregulate the NK cell‐associated receptors and transcription factors, lyse NK‐cell targets, and are reprogrammed into NK‐like cells (ITNKs) upon deletion of MTA2, MBD2, CHD4, or BCL11B. ITNKs increase OPA1 expression and exhibit characteristically elongated mitochondria with augmented oxidative phosphorylation (OXPHOS) activity. OPA1‐mediated elevated OXPHOS enhances cellular acetyl‐CoA levels, thereby promoting the reprogramming efficiency and antitumor effects of ITNKs via regulating H3K27 acetylation at specific targets. In conclusion, our findings demonstrate that the NuRD complex and BCL11B cooperatively maintain T‐cell fate directly by repressing NK cell‐associated transcription and indirectly through a metabolic‐epigenetic axis, providing strategies to improve the reprogramming efficiency and antitumor effects of ITNKs.
Programa de salud cardiovascular: atenciones en Santiago de Chile en contexto de pandemia
Authors: Torres Reyes Wladimir Esteban , De La Fuente Álvarez Felipe , Benavides Carla , Montecinos-Guiñez Daniela 
Published: September 2023

Introducción: Las enfermedades cardiovasculares son una de las principales causas de morbilidad y mortalidad en las Américas y en Chile. La pandemia por COVID-19 ha impactado la oferta de servicios de salud en la atención primaria, afectando el cuidado de las comunidades con alta prevalencia de enfermedades crónicas. En Chile, el Programa de Salud Cardiovascular brinda atención multiprofesional a personas con estas enfermedades en la atención primaria.
Objetivo: Describir la variación de las prestaciones de servicios del Programa de Salud Cardiovascular en las comunas de la provincia de Santiago de Chile, durante el periodo 2014-2020 y su relación con la pobreza multidimensional en el periodo de pandemia.
Método: Estudio descriptivo y ecológico. Se analizó la variación porcentual de las atenciones de enfermería, medicina y nutrición para cada comuna de la provincia de Santiago durante 2014-2020, utilizando registros del Ministerio de Salud de Chile. Se indagó en la variación 2019-2020 como descripción de la provisión de servicios del Programa de Salud Cardiovascular durante el primer año de pandemia y se analizó su asociación con la pobreza multidimensional.
Resultados: La pandemia por COVID-19 impactó fuertemente en las atenciones del Programa de Salud Cardiovascular en la provincia de Santiago. Los controles disminuyeron en promedio un 60.43 %. Los controles de nutrición fueron los más afectados y los menos afectados los controles por medicina. Este impacto no se asoció con el nivel de pobreza multidimensional de cada comuna.
Conclusiones: La magnitud en la disminución de atenciones revela la importancia de realizar vigilancia a la oferta de atenciones y ofrece una oportunidad para adelantarse a las consecuencias que esto implica.
MANDİBULAR SUBKONDİLER KIRIKLARDA TEDAVİ YAKLAŞIMLARI İLE KOMPLİKASYONLAR ARASINDAKİ İLİŞKİ
Authors: TAPAN Mehmet , ERGANİ Hasan Murat 
Published: September 2023

Amaç
Mandibula kondil kırıkları, mandibulada en sık görülen
kırık türlerinden biri olmasına rağmen tedavisi
tartışmalıdır. Bu çalışmanın amacı tedavi yönteminin
güvenliğini belirlemek, postoperatif komplikasyonları
azaltmak ve klinik deneyimimizi anlatmaktır.
Gereç ve Yöntem
Subkondiler mandibular kırığı olan 53 hasta dahil edildi.
Hastalar kapalı redüksiyon (KR) veya açık redüksiyon
ve internal fiksasyon (ARIF) ile tedavi edildi. Tüm
hastalarda intermaksiller fiksasyon (IMF) için arch bar
veya intermaksiller vidalar ve lastik kullanıldı. Ardından
istatistiksel analiz yapıldı.
Bulgular
Çalışmaya toplam 37 erkek hasta ve 16 kadın hasta
dahil edildi. Çalışmada mandibula kırıklarının en sık
nedeni düşmelerdi (n=23; %43,3). Ameliyat sonrası
komplikasyonlar arasında maloklüzyon, temporomandibular
disfonksiyon (ağız açıklığının 30 mm'den az
olması), fasiyal sinir nöropraksisi ve enfeksiyon yer
alıyordu. Ameliyat sonrası maloklüzyon komplikasyonu
açısından KR ve ARIF grupları arasında istatistiksel
olarak anlamlı bir fark yoktu.Maloklüzyona sahip
hastaların tamamında (n=8) eşlik eden kırıklar (n=23)
mevcuttu. Ameliyat sonrası maloklüzyon komplikasyonu
açısından alt gruplar (eşlik eden kırığı olan grup ve
eşlik eden kırığı olmayan grup) arasında istatistiksel
olarak anlamlı fark vardı. Ortalama 21 günlük bir süre
de her zaman temporomandibular disfonksiyon ile ilişkilendirilmiştir
Sonuç
Bu çalışma, uygun tedavi seçiminin belirlenmesinde
avantaj ve dezavantajları dengelemenin gerekliliğini
ortaya koymuştur. ARIF'in birçok avantajı vardır; ancak
ameliyat sonrası komplikasyonlar da eşlik edebilir.
IMF'nin kullanım süresi fonksiyonel bozukluklara yol
açabileceğinden hastaların tedavi kararında hekimlerle
iş birliği yapması gerekmektedir.
Sistem Informasi Berbasis Bot Telegram Sebagai Media Sosialisasi Keselamatan Berkendara
Authors: Reynaldi Muhammad , Al Khairi Syihan , Hendarman Naufal Geraldi , Nugroho Fityandhiya Islam 
Published: September 2023

Keselamatan berkendara merupakan perilaku berkendara secara ideal yang harus dipahami oleh pengguna kendaraan. Perilaku ini sering dikampanyekan pemerintah indonesia kepada seluruh lapisan masyarakat. Sampai saat ini banyak orang mengendarai kendaraan tapi tidak semua orang memahami cara mengendarai kendaraan dengan baik dan benar serta memperhatikan sisi keamanan dan keselamatan. Baik itu keamanan untuk diri sendiri maupun sisi keamanan bagi pengguna jalan lainnya. Hal ini dikarenakan banyak masyarakat Indonesia yang belum sadar akan pentingnya pengetahuan mengenai keselamatan berkendara. Oleh karena itu, perlu suatu cara yang efektif untuk mengedukasi masyarakat tentang pentingnya pengetahuan keselamatan berkendara sehingga dapat mengimplementasikanya dalam berkendara dengan baik dan aman. Di sisi lain, masyarakat Indonesia banyak yang menjadi pengguna aplikasi Telegram sebagai media komunikasi. Dengan memanfaatkan potensi tersebut, maka kami mengusulkan sebuah sistem informasi keamanan berkendara yang diberi nama “Safety Riding Advice System (SRAS)”. Sistem informasi ini dibangun dengan memanfaatkan fitur Bot pada aplikasi Telegram. SRAS dapat memberikan informasi kepada pengguna mengenai hal-hal terkait keamanan dan keselamatan berkendara. Metode perancangan sistem informasi SRAS menggunakan yang model prototype’ yang terdiri dari beberapa tahapan diantarannya yaitu (1) analisis kebutuhan sistem, (2) perancangan sistem, dan (3) evaluasi.
Analisis User Interface Terhadap Website Badan Pusat Statistik Kota Balikpapan Dengan Menggunakan Metode Heuristic Evaluation
Authors: Auliya Ridha , Natasia Sri Rahayu , Nur Rachma Intan Wahyu , Ma’arif Mahiza Imam , Faizah Maulidhiyah , Ibnu Azmi Moch. Fattah 
Published: September 2023

Badan Pusat Statistik adalah Lembaga Pemerintah Non Kementerian yang bertanggung jawab langsung kepada Presiden. Website Badan Pusat Kota Balikpapan menyediakan data statistic berkualitas untuk Indonesia maju. Tentunya website Badan Pusat Statistik Kota Balikpapan menjadi salah satu interaksi bagi penggunanya. Beberapa fitur-fitur dari website Badan Pusat Statistik Kota Balikpapan yang ditampilkan seperti berita, informasi kependudukan, informasi ekonomi dan masih banyak fitur yang berguna bagi pengguna. Unstuck melakukan analisis terhadap website Badan Pusat Statistik Kota Balikpapan, penelitian ini menggunakan metode Heuristic Evaluation. Permasalahan terhadap user interface yang ada pada website tersebut ialah fitur pencarian yang sulit digunakan dan rumit karena harus menggunakan captcha. Selain itu, saat mengubah tampilan website menjadi berbahasa inggris, terdapat data informasi terbaru yang tidak ditampilkan dan tampilan user interface yang kurang efisien seperti navigasi yang kurang rapi, fitur ekspansi sidebar dengan 2 tombol yang memiliki fungsi sama, terdapat media gambar yang tidak muncul pada tampilan, dan beberapa dokumen publikasi yang tidak dapat diunduh. Hal ini membuat pengguna merasa kurang nyaman dengan user interface pada website balikpapankota.bps.go.id. Penelitian ini memperoleh tingkat permasalahan pengguna berdasarkan severity rating pada heuristic evaluation, sehingga menghasilkan sebanyak 4 rekomendasi desain tampilan perbaikan untuk desktop website balikpapankota.bps.go.id, dan 6 rekomendasi desain tampilan perbaikan untuk mobile website balikpapankota.bps.go.id dan rekomendasi perbaikan tampilan berupa rancangan mockup dan prototype yang telah dievaluasi oleh kelompok atau evaluator untuk dijadikan sebagai acuan referensi dalam melakukan proses redesign website balikpapankota.bps.go.id
VISIBILIDAD DE LO INDÍGENA O LA INDEPENDENCIA DE PENSAMIENTO DE EUGENIO DÍAZ CASTRO EN MANUELA
Authors: Neira Raúl 
Published: September 2023

Díaz Castro denuncia en Manuela la posición que la élite neogranadina había adoptado sobre el indígena como miembro de la sociedad que se deseaba conformar, ubicándolo entre la antigüedad y la alteridad. Con su representación narrativa sobre esta situación, explicita la grave problemática social que enfrentaba la Nueva Granada al continuar con la injusticia y el desequilibrio social; así reclama la necesidad de efectuar cambios legales y sociales.
ENTONACIÓN DEL ENUNCIADO INTERROGATIVO EN EL ESPAÑOL DE LA CIUDAD DE MEDELLÍN
Authors: Osorio Gloria Matilde , Muñoz Builes Diana 
Published: September 2023

El presente artículo expone los patrones entonativos obtenidos mediante rastreos televisivos en enunciados interrogativos elípticos y no elípticos de los hablantes de español de la ciudad de Medellín. Los resultados obtenidos permiten afirmar que la entonación en los enunciados interrogativos parciales y totales es cadente, contrario a las interrogativas elípticas que presentan una inflexión final ascendente. Esta investigación contribuye a tener un conocimiento de la diversidad lingüística característica de los diferentes grupos culturales que conforman la identidad nacional.
Carbonatogénesis induced in a profile of tropical soil
Authors: Valencia González Yamile , Camapum de Carvalho Jose , Lara Valencia Luis Augusto 
Published: September 2023

In soils can be generated a natural process called “biomineralization” or “bioprecipitation” by which living organisms produce crystalline or amorphous mineral precipitates. This process is very important in geotechnical engineering because the mineral precipitates can fill the gaps or link soil particles to improve geological and geotechnical properties of the material; however, the process can take many years to occur naturally. Is for this reason that this study seeks to induce in few days (15 days) the calcium carbonate minerals precipitation, based on the addition of a nutrient precipitator over existing native bacteria in a tropical soil profile, improving their engineering properties through the reduction of the void index, shrinkage, permeability, collapse, erodibility and breakdown, and the increase of friction angles and cohesion, producing less environmental impact than other techniques commonly used in engineering.
Impact of wind power in middle–termed hydrothermal dispatch
Authors: Martínez-Ramírez María Victoria , Garcés Alejandro , Ramos Sandro 
Published: September 2023

This paper describes a linear programming model and Monte Carlo simulation which solve a middle-termed hydrothermal dispatch problem for three different scenarios of wind power penetration. Transmission line effects are neglected. The fuel cost in thermal plants varies in each time period. The test system has two thermal and three hydroelectric plants that can continuously operate during the twelve-months planning term. Wind generation is modeled by using Weibull Distribution Functions particular to the Colombian system, while hydro-generation is modeled by Normal Distribution Functions. Results show costs reduction for the three scenarios of wind power penetration. The main contribution of this paper is to simultaneously introduce the stochastic effect of wind and hydrology in the hydrothermal dispatch.
Air Watch: An Ample Design of Indoor Air Quality Monitoring System
Authors: Theresa W. Gracy , Tamilselvi T. , Florence M. Mary Victoria , Revathi K. 
Published: September 2023

The environment is getting contaminated drastically by introducing harmful materials into the atmosphere through the excessive activities of human in adding comfort and luxurious style in their living. The pollutant level in air has high impact of healthiness of the person inhaling it. Air not outside as well indoor is infected by various hazardous particles and gases. To assess the air quality in the particular environment, it stimulates the need to monitor the hazardous elements listed. The internet of things (IoT) and artificial intelligence (AI) became the part of human life by adding smartness in their daily routines from facilitating control over appliances to own health factor as well automate operations. The primary objective of the effort is to identify the gases that cause air pollution, measure the air quality, and assess the level of pollution so that we can determine which gases cause pollution and at what place is the air being impacted. An IoT based indoor air quality monitoring system is built through incorporating carbon monoxide (CO), carbon dioxide (CO2), Ozone (O3), particulate matters (PM) and volatile organic components (VOC) sensors into Arduino board. The design ensures a complete air monitor, extends reliable service at low cost. A rule based system is developed to automate events upon the estimated air quality index (AQI) out of the sensory circuit.
Optimal and Efficient Searchable Encryption with Single Trapdoor for Multi-Owner Data Sharing in Federated Cloud Computing
Authors: Veerabhadram Vadlamani , Arul Dalton Gregory 
Published: September 2023

Cloud computing, an Internet based computing model, has changed the way of data owners store and manage data. In such environment, data sharing is very important with more efficient data access control. Issuing an aggregate key to users on data enables and authorizes them to search for data of select encrypted files using trapdoor or encrypted keyword. The existing schemes defined for this purpose do have certain limitations. For instance, Cui et al. scheme is elegant but lacks in flexibility in access control in presence of multiple data owners sharing data to users. Its single trapdoor approach needs transformation into individual trapdoors to access data of specific data owner. Moreover, the existing schemes including that of Cui et al. does not support federated cloud. In this paper we proposed an efficient key aggregate searchable encryption scheme which enables multiple featuressuch as support for truly single aggregate key to access data of many data owners, federated cloud support,query privacy, controlled search process and security against cross-pairing attack. It has algorithms for setup, keygen, encrypt, extract, aggregate, trapdoor, test and federator. In multi-user setting it is designed to serve data owners and users with secure data sharing through key aggregate searchable encryption The proposed scheme supports federated cloud. Experimental results revealed that the proposed scheme is provably secure withrelatively less computational overhead and time complexity when compared with the state of the art.
Optimized Ensemble Approach for Multi-model Event Detection in Big data
Authors: Swapnika K. , Vasumathi D. 
Published: September 2023

Event detection acts an important role among modern society and it is a popular computer process that permits to detect the events automatically. Big data is more useful for the event detection due to large size of data. Multimodal event detection is utilized for the detection of events using heterogeneous types of data. This work aims to perform for classification of diverse events using Optimized Ensemble learning approach. The Multi-modal event data including text, image and audio are sent to the user devices from cloud or server where three models are generated for processing audio, text and image. At first, the text, image and audio data is processed separately. The process of creating a text model includes pre-processing using Imputation of missing values and data normalization. Then the textual feature extraction using integrated N-gram approach. The Generation of text model using Convolutional two directional LSTM (2DCon_LSTM). The steps involved in image model generation are pre-processing using Min-Max Gaussian filtering (MMGF). Image feature extraction using VGG-16 network model and generation of image model using Tweaked auto encoder (TAE) model. The steps involved in audio model generation are pre-processing using Discrete wavelet transform (DWT). Then the audio feature extraction using Hilbert Huang transform (HHT) and Generation of audio model using Attention based convolutional capsule network (Attn_CCNet). The features obtained by the generated models of text, image and audio are fused together by feature ensemble approach. From the fused feature vector, the optimal features are trained through improved battle royal optimization (IBRO) algorithm. A deep learning model called Convolutional duo Gated recurrent unit with auto encoder (C-Duo GRU_AE) is used as a classifier. Finally, different types of events are classified where the global model are then sent to the user devices with high security and offers better decision making process. The proposed methodology achieves better performances are Accuracy (99.93%), F1-score (99.91%), precision (99.93%), Recall (99.93%), processing time (17seconds) and training time (0.05seconds). Performance analysis exceeds several comparable methodologies in precision, recall, accuracy, F1 score, training time, and processing time. This designates that the proposed methodology achieves improved performance than the compared schemes. In addition, the proposed scheme detects the multi-modal events accurately.
Impact of Feature Representation on Remote Sensing Image Retrieval
Authors: Mahajan Monali P. , Kamalapur S. M. 
Published: September 2023

Remote sensing images are acquired using special platforms, sensors and are classified as aerial, multispectral and hyperspectral images. Multispectral and hyperspectral images are represented using large spectral vectors as compared to normal Red, Green, Blue (RGB) images. Hence, remote sensing image retrieval process from large archives is a challenging task. Remote sensing image retrieval mainly consist of feature representation as first step and finding out similar images to a query image as second step. Feature representation plays important part in the performance of remote sensing image retrieval process. Research work focuses on impact of feature representation of remote sensing images on the performance of remote sensing image retrieval. This study shows that more discriminative features of remote sensing images are needed to improve performance of remote sensing image retrieval process.
Security and Privacy in Smart Farming: Challenges and Opportunities
Authors: Rao N. Raghava , Kovoor Madhuri , Kumar G. Nanda Kishor , Parameswari D.V. Lalita 
Published: September 2023

Agriculture is basic source of livelihood of people in india. It plays major role in economy of country. But now a days due to migration of people from rural to urban there is hindrance in agriculture.Monitoring the environmental factor is not the complete solution to increase the yield of crops.There are number of factors that decrease the productivity to a great extent. Hence automation must be implemented in agriculture to overcome these problems.An automation Irrigation system there by saving time ,money and power of farmer.The traditional farm land irrigation techniques require manual intervention.With the automated technology of irrigation,the human intervention can be minimized.Continuous sensing and monitoring of crops by convergence of sensors with Internet Of Things(IOT) and making farmers aware about crops growth,harvest time periodically and in turn making high productivity of crops and also ensuring correct delivery of products to end,consumers at right place and right time. So to overcome this problem we go for smart agriculture technique using IOT.This project includes sensors such as temperature,humidity,soil moisture for collection of field data and processed.These sensors are combined with well established web technology in the form of wireless sensor networks to remotely control and monitor data from the sensors.