bluuebunny/crossref_metadata_2025_split huggingface dataset:
A novel hybrid deep learning approach for 5G network traffic control and forecasting
Authors: Dangi Ramraj , Lalwani Praveen 
Published: December 2022

Summary5G is planned to link not just traditional devices such as tablets and smartphones, but also smart devices, smart homes, autonomous vehicles, and industry 4.0 which significantly increases the amount of traffic over the network. Network function virtualization and software defined networks will be used heavily to create scalably and on‐demand 5G architecture using virtual network functions. In this article, we proposed a unique approach to scaling 5G core network resources by predicting traffic load fluctuations using a hybrid model. Most researchers have presented deep learning models to anticipate regular traffic to improve services, however, these recommended models have failed to estimate traffic load during festivals to unexpected changes in traffic conditions. To solve this issue, we introduced CNN+LSTM, a hybrid model that combines CNN, and LSTM to forecast cumulative network traffic across particular intervals to scale up and properly estimate the availability of 5G network resources by leveraging traffic load variations. The suggested model surpasses the other tested deep learning models and existing techniques that forecast the output in both normal and abnormal traffic conditions, according to a comparison of the produced output with existing techniques.
Better Accounting Needed to Solve Looming Groundwater Crisis
Authors: Sever Megan 
Published: December 2022

AbstractAcross the U.S., we are withdrawing water far faster than our aquifers are naturally replenished. One of the challenges of determining how much water is left in aquifers is that decline rates are extremely variable over space and time and regulations governing groundwater withdrawal are highly localized. Over the long term, pumping water out of the ground faster than it’s replenished is like deficit spending; it will catch up with you. Earn 1 CEU in Soil & Water Management by reading this article and taking the quiz at https://web.sciencesocieties.org/Learning‐Center/Courses.
A case of esophageal carcinoma on esophageal varices treated by endoscopic submucosal dissection after endoscopic injection sclerotherapy
Authors: Nakachi Kenichiro , Maekita Takao , Deguchi Hisanobu , Kimura Masatomo , Iguchi Mikitaka , Yoshida Satoshi , Kitano Masayuki 
Published: December 2022

AbstractEsophageal varices (EVs) are often treated using endoscopic injection sclerotherapy. Endoscopic submucosal dissection (ESD) has been used for early esophageal epithelial neoplasia worldwide. We report a case of early esophageal squamous cell carcinoma (ESCC) that occurred over EVs, in which the EVs were treated with endoscopic injection sclerotherapy before the early ESCC was treated with endoscopic submucosal dissection. Argon plasma coagulation was finally performed to prevent the recurrence of varices. No serious complications, such as severe bleeding or perforation, were observed. Histopathological examination revealed submucosal veins occluded with an organized thrombus for which endoscopic injection sclerotherapy with an intravariceal injection of sclerosant had been performed, but no fibrosis was observed outside the blood vessels. This explains that the injected sclerosant into EVs did not cause any tissue reaction like fibrosis in the submucosa surrounding the vein, which may have made endoscopic submucosal dissection safer and easier. Varices have not recurred, and ESCC has also not recurred for 5 years. We demonstrated a successful treatment of ESCC on EVs and no submucosal fibrosis other than inside the occluded vessels and verified it histologically.
An environmental, energy, and economic efficiency analysis for the energy market in European Union
Authors: Gökgöz Fazıl , Yalçın Engin 
Published: December 2022

AbstractEnergy and environmental issues have been high on agendas of European Union members since they are intertwined with efforts to mitigate climate change and expand the economy. We intend to analyze the energy and environmental efficiency of EU countries using enhanced data envelopment analysis techniques. First, our study investigates energy efficiencies using the bootstrap DEA technique, which addresses the problem of statistical noise. Further, we examine the environmental and eco‐innovation efficiency of EU countries by employing the two‐stage super‐slack‐based DEA technique, which is one of the most suitable approaches for modeling undesired output. According to the environmental efficiency findings, the Nordic countries are primarily more efficient whereas, in terms of eco‐innovation efficiency, Germany is ranked as the top‐performing country. In addition, substantial prospects for improvements exist in the efficiency of the EU countries We may conclude that this research will help policymakers in this area.
Influence of environmental factors on electricity generation performance of electricity‐producing bacteria from oily sludge microbial fuel cells
Authors: Guo Haiying , Huang Chunfeng , Jia Xinlei , Geng Xiaoheng , Huo Hongjun , Yang Zhaoyang , Han Binpeng 
Published: December 2022

AbstractElectricity‐generating bacteria are used as the biocatalysts of microbial fuel cells (MFCs). The power‐generating properties of electricity‐generating bacteria play an important role in organic matter degradation and electricity generation of MFCs. However, there are few electricity‐producing bacteria isolated from the anode biofilm of microbial fuel cells containing oily sludge. More importantly, the adaptability of nitrogen‐to‐phosphorus ratio, temperature and pH of the electricity‐generating bacteria were adjusted by controlled variable method. The results of this study showed that the isolated electricity‐producing bacteria (Citrobacter freundii) with a rod‐shaped cell, wrinkled surface, about 0.5–1.0 μm in length. The optimal nitrogen‐to‐phosphorus ratio, temperature and pH of MFCs are 5.67:1, 25°C, and pH = 7.5, Its maximum voltage and power density was up to 143.01 mV and 65 mW·m−3, respectively. Furthermore, the growth rate of the electricity‐producing bacteria is the highest. This lays the foundation for inoculating electricity‐generating bacteria into oily sludge MFCs to improve the oil removal and power generation performance.
Particle swarm optimization of phase change and indoor setpoint temperatures in a phase change material‐air heat exchanger for free cooling of two climate zones
Authors: Dastmalchi Majid , Boyaghchi Fateme Ahmadi 
Published: December 2022

AbstractThe simulation and free‐cooling economic optimization of a phase change material (PCM)‐air heat exchanger (PAHX), including containers filled with fictitious SiO2 nano‐enhanced PCM (NEPCM), are investigated. The airside, PCM side and heat balance governing equations are solved numerically by employing analytical solutions during the 3‐month summer from June 22 to September 22. Two climate zones of Tehran and Mashhad have been selected due to temperature contrast, especially at off‐peak times. Particle swarm optimization is employed to determine indoor setpoint temperatures (SPTs) and phase change temperatures (PCTs) to optimize the total cooling energy cost of a residential building. The effects of local climate, airflow rate, nanoparticle concentrations, and SPT range on optimization variables are studied. Two SPTs for day and night and two PCTs for melting and solidifying are between 22°C and 26°C. The mass percentage of nanoparticles is considered to be from 0% to 14%. Based on optimization analysis, Toff‐peak = 22°C, and Tpeak = 26°C are considered the best SPTs for both cities, for Mashhad Ts = 24.05°C, Tl = 18.97°C while for Tehran Ts = 24.83°C, Tl = 25.35°C are considered as the best PCTs. The optimum electrical cost increases significantly with increasing airflow rate and SPT range, while nanoparticle concentration has a low influence of up to about 3% for all desired days.
Altered lateralization of the cingulum in deployment‐related traumatic brain injury: An ENIGMA military‐relevant brain injury study
Authors: Dennis Emily L. , Newsome Mary R. , Lindsey Hannah M. , Adamson Maheen , Austin Tara A. , Disner Seth G. , Eapen Blessen C. , Esopenko Carrie , Franz Carol E. , Geuze Elbert , Haswell Courtney , Hinds Sidney R. , Hodges Cooper B. , Irimia Andrei , Kenney Kimbra , Koerte Inga K. , Kremen William S. , Levin Harvey S. , Morey Rajendra A. , Ollinger John , Rowland Jared A. , Scheibel Randall S. , Shenton Martha E. , Sullivan Danielle R. , Talbert Leah D. , Thomopoulos Sophia I. , Troyanskaya Maya , Walker William C. , Wang Xin , Ware Ashley L. , Werner John Kent , Williams Wright , Thompson Paul M. , Tate David F. , Wilde Elisabeth A. 
Published: December 2022

AbstractTraumatic brain injury (TBI) in military populations can cause disruptions in brain structure and function, along with cognitive and psychological dysfunction. Diffusion magnetic resonance imaging (dMRI) can detect alterations in white matter (WM) microstructure, but few studies have examined brain asymmetry. Examining asymmetry in large samples may increase sensitivity to detect heterogeneous areas of WM alteration in mild TBI. Through the Enhancing Neuroimaging Genetics Through Meta‐Analysis Military‐Relevant Brain Injury working group, we conducted a mega‐analysis of neuroimaging and clinical data from 16 cohorts of Active Duty Service Members and Veterans (n = 2598). dMRI data were processed together along with harmonized demographic, injury, psychiatric, and cognitive measures. Fractional anisotropy in the cingulum showed greater asymmetry in individuals with deployment‐related TBI, driven by greater left lateralization in TBI. Results remained significant after accounting for potentially confounding variables including posttraumatic stress disorder, depression, and handedness, and were driven primarily by individuals whose worst TBI occurred before age 40. Alterations in the cingulum were also associated with slower processing speed and poorer set shifting. The results indicate an enhancement of the natural left laterality of the cingulum, possibly due to vulnerability of the nondominant hemisphere or compensatory mechanisms in the dominant hemisphere. The cingulum is one of the last WM tracts to mature, reaching peak FA around 42 years old. This effect was primarily detected in individuals whose worst injury occurred before age 40, suggesting that the protracted development of the cingulum may lead to increased vulnerability to insults, such as TBI.
Sex disparity of cerebral white matter hyperintensity in the hypertensive elderly: The Shanghai Changfeng study
Authors: Wang Liangqi , Lin Huandong , Zhao Zehua , Chen Lingyan , Wu Li , Liu Ting , Li Jing , Huang Chu‐Chung , Peng Yifeng , Lo Chun‐Yi Zac , Gao Xin 
Published: December 2022

AbstractWhite matter hyperintensity (WMH) is associated with vascular hemodynamic alterations and reflects white matter injury. To date, the sex difference of tract‐specific WMH and the relationship between high blood pressure (BP) and tract‐specific WMH remain unclear. We recruited 515 subjects from the Shanghai Changfeng study (range 53–89 years, mean age 67.33 years). Systolic and diastolic blood pressure (SBP and DBP) were collected and used to calculate pulse pressure (PP). Magnetic resonance T1 and T2 FLAIR images were acquired to measure WMH and calculate WMH index. The ANCOVA test was performed to test the difference between sexes, and the linear regression model was used to examine the associations between BP and WMH index. Men showed higher WMH index than women in all white matter tracts (p < .001, respectively) except for the bilateral superior longitudinal fasciculus (SLF) and its left temporal part (tSLF). High SBP and PP was associated with a lower WMH index on the left corticospinal tract (CST), SLF, tSLF and right cingulum in hippocampus (p ≤ .001, respectively) in women, while high DBP was associated with a higher WMH index on the bilateral CST (left p < .001; right p = .001), left inferior longitudinal fasciculus (p < .001) and inferior fronto‐occipital fasciculus (p = .002) in men. Men tend to have more WMH compared to women. A high SBP/PP relates to a lower WMH burden in women. This suggests that women could benefit from higher blood pressure in older age.
Childhood exposure to birth registration laws and old‐age mortality
Authors: Noghanibehambari Hamid , Fletcher Jason 
Published: December 2022

AbstractThis paper studies the effects of the enactment of birth registration laws, as the official universal and uniform method of recording births, across US states in the first decades of the 20th century on old‐age longevity for children affected by these laws. We show that establishing birth registration laws has long‐term benefits for old‐age health. The benefits are primarily driven by states with an effective child labor policy, suggesting that registering births helps the enforcement of child labor laws which in turn operate as the mechanism channel to improve old‐age longevity. A treatment‐on‐treated calculation suggests an increase of 0.6 years of longevity from not working during childhood due to the birth registration law.
Characterization of the aroma profile of quinoa (Chenopodium quinoa Willd.) and assessment of the impact of malting on the odor‐active volatile composition
Authors: Almaguer Cynthia , Kollmannsberger Hubert , Gastl Martina , Becker Thomas 
Published: December 2022

AbstractBackgroundQuinoa (Chenopodium quinoa Willd.) is a gluten‐free pseudocereal, rich in starch and high‐quality proteins. It can be used as a cereal. Recently, a variety of nontraditional food products were developed; however, the sharp bitterness and the earthy aroma of unprocessed quinoa interfered with the acceptance of these products. Malting of cereals is known to improve their processing properties and enhance their sensory quality. To evaluate the acceptance and potential of quinoa malt as a raw material for beverage production, malt quality indicators (e.g., soluble protein) and the aroma profiles of different quinoa malts were compared.ResultsInitial sensory assessment of quinoa in its native and malted state identified differences in their aroma profiles and revealed that pleasant nutty and caramel aromas were formed by malting. Subsequently, three complementary isolation techniques and gas chromatography‐olfactometry/mass spectrometry (GC‐O/MS) were used for volatile analysis. Instrumental analysis detected 34 and 62 odor‐active regions in native quinoa and quinoa malt, respectively. In the second part, storage and the impact of three malting parameters on volatile formation were examined. By varying the malting parameters, seven additional odor‐active malting byproducts were revealed.ConclusionThree naturally occurring methoxypyrazines were identified as important contributors to the characteristic quinoa aroma. In all fresh quinoa malts a similar number of volatile compounds was perceived but their intensity and composition varied. Higher germination temperature promoted the formation of lipid oxidation products. Fatty smelling compounds and carboxylic acids, formed during storage, were classified as aging indicators of quinoa malt. © 2022 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Audiometric and Otologic Findings in Children and Young Adults with Neurofibromatosis Type 1 and Plexiform Neurofibromas
Authors: Idowu Victoria , Christensen Julie , Gross Andrea M. , Dombi Eva , Miles Jennifer R , King Kelly , Chisholm Jennifer , Zalewski Christopher , Baldwin Andrea , Whitcomb Patricia , Burgess Crystal , Widemann Brigitte C , Brewer Carmen C , Kim Hung Jeffrey 
Published: December 2022

ObjectivesTo characterize otologic and audiologic manifestations in our NF1 cohort and explore the relationship between otologic and audiologic findings in a subset of patients with ear‐related plexiform neurofibromas (PNs).MethodsAudiologic and otologic clinical evaluations were conducted on 102 patients with NF1 in a natural history study (5–45 years; M = 14.4 years; Mdn = 14). Testing included pure tone and speech audiometry, middle ear function, neurodiagnostic auditory brainstem response (ABR), auditory processing, and MRIs of the head and neck region. Patients referred to this study had an overall higher incidence and burden of PNs than the overall NF1 population.ResultsThe majority of subjects in this cohort had normal hearing sensitivity (81%) and normal middle ear function (78%). Nineteen participants had hearing loss that ranged in degree from mild to profound, with the majority in the mild range. Hearing loss was twice as likely to be conductive than sensorineural. In patients with ear‐related PNs (n = 12), hearing loss was predominantly conductive (60%). Seventy‐five percent of ears with PNs had atypical tympanometric tracings that could not be characterized by the classic categories. In all 20 patients with a PN in the temporal bone, the ear canal was affected, and the PNs often extended to the surrounding soft tissue regions.ConclusionsPeople with NF1‐related PNs in the temporal bone and adjacent skull base should have audiometric and otologic monitoring. Addressing hearing concerns should be part of routine clinical evaluations in patients with NF1. Magnetic resonance imaging (MRI) should be performed in patients with NF1 who have hearing loss.Level of Evidence3 Laryngoscope, 133:2770–2778, 2023
Simplified method for three‐dimensional slope stability analysis based on rigorous limit equilibrium
Authors: Zhu Dayong , Wang Linghui , Lu Kunlin 
Published: December 2022

AbstractA simplified procedure is presented for calculating the factor of safety of a slope with a 3‐D slip surface, which satisfies all the six equilibrium conditions for the 3‐D sliding body. By assuming an initial normal stress distribution on the 3‐D slip surface which is then modified by a polynomial function involving five correcting parameters, the six equilibrium equations are established with a prescribed value of factor of safety, which is linear with the five correcting parameters as well as the horizontal seismic coefficient Kc. An iterative procedure is proposed for determining the factor of safety with a prescribed value of Kc, and ensuring that the normal stresses are positive on the whole slip surface. The method is suitable for analyzing 3‐D slope stability, especially with unsymmetric 3‐D shapes, and its application in practical engineering is given, which demonstrates the effectiveness of the present method.
Polyimide dielectric nanocomposites containing functional nanofillers based on multilayer structure: Design, preparation, and properties
Authors: Zhang Ai Ping , Li Xin Kang , Lin Hai Lan , Zhang Zhao Xin , Yang Shang Ke , Zhang Xun Tao , Xiao Liu Xin , Bian Jun , Chen Dai Qiang 
Published: December 2022

AbstractPolyimide (PI) dielectric nanocomposites containing functional nanofillers based on layered structure (single‐layer: BT@Al2O3@PI, double‐layer: PI/BT@Al2O3@PI, three‐layer: PI/BT@Al2O3@PI/PI) were designed and prepared by using PI as matrix, barium titanate (BT)@alumina (Al2O3) as nanofillers through in‐situ polymerization compounding technology. FTIR tests indicated that PI and PI dielectric nanocomposites have been synthesized successfully. The molecular mass of BaTiO3@Al2O3@PAA oligomer was higher than that of pure PAA when BT and Al2O3nanofillers were incorporated simultaneously, as verified by GPC and intrinsic viscosity tests. XRD analysis showed that the addition of nanofillers destroyed the order of PI molecular structure and reduced the arrangement density of PI molecular chains. Both FESEM and HRTEM observations showed that the nanofillers were homogeneously dispersed in the PI matrix, contributing to the property improvements of PI dielectric nanocomposites. TGA results indicated that adding nanofillers improved the thermal stability and heat resistance of PI dielectric nanocomposites. The dielectric constant of PI/BT@Al2O3@PI double‐layer nanocomposites was between the single‐layer nanocomposites and pure PI. Due to the effective medium theory, the dielectric constant of three‐layer PI/BT@Al2O3@PI/PI nanocomposites containing 5 wt% BT@Al2O3reached 5.43. This work can be expected to provide an effective strategy to fabricate PI dielectric nanocomposite films for energy storage applications.
Total saponins of panax ginseng via the CX3CL1/CX3CR1 axis attenuates neuroinflammation and exerted antidepressant‐like effects in chronic unpredictable mild stress in rats
Authors: Qin Meng , Chen Chen , Wang Ning , Yu Di , Yu Shangmin , Wang Xinying , Liu Tongyan , Lv linlin , Guan Qingxiang 
Published: December 2022

AbstractTotal saponins of Panax ginseng (TSPG) have antidepressant effects. However, the underlying antidepressant mechanism of TSPG remains not clear. This study aimed to predict the mechanism of TSPG by bioinformatics analysis and to verify it experimentally. Bioinformatics analysis showed that the antidepressant effects of TSPG may be related to inflammation, and CX3CL1/CX3CR1 may play a key mediating role. Wistar rats were exposed to chronic unpredictable mild stress (CUMS) for 6 weeks, and TSPG (50 mg/kg/d, 100 mg/kg/d) was administered throughout the modeling period. It was found that TSPG improves depressive behavior and reduces neuropathic damage in the hippocampus in rats. Meanwhile, TSPG decreased mRNA and protein expression of pro‐inflammatory cytokines and CX3CL1/CX3CR1 and inhibited P38 and JNK protein phosphorylation in the hippocampus. Rat astrocytes were employed to explore further the potential mechanism of TSPG in regulating CX3CL1/CX3CR1. The results showed that CX3CL1 small interfering RNA (siRNA‐CX3CL1) and CX3CR1 inhibitor (JMS‐17‐2) had similar effects to TSPG, that is, reduced inflammatory response, reactive oxygen species (ROS), and phosphorylation of P38 and JNK proteins, while overexpression of CX3CL1 (pcDNA‐CX3CL1) counteracted the above effects of TSPG. It is suggested that the antidepressant effect of TSPG may be achieved through inhibition of CX3CL1/CX3CR1.
Echocardiographic estimation of pulmonary vascular resistance in advanced lung disease
Authors: DesJardin Jacqueline T. , Svetlichnaya Yana , Kolaitis Nicholas A. , Hays Steven R. , Kukreja Jasleen , Schiller Nelson B. , Zier Lucas S. , Singer Jonathan P. , De Marco Teresa 
Published: December 2022

AbstractNoninvasive assessment of pulmonary hemodynamics is often performed by echocardiographic estimation of the pulmonary artery systolic pressure (ePASP), despite limitations in the advanced lung disease population. Other noninvasive hemodynamic variables, such as echocardiographic pulmonary vascular resistance (ePVR), have not been studied in this population. We performed a retrospective analysis of 147 advanced lung disease patients who received both echocardiography and right heart catheterization for lung transplant evaluation. The ePVR was estimated by four previously described equations. Noninvasive and invasive hemodynamic parameters were compared in terms of correlation, agreement, and accuracy. The ePVR models strongly correlated with invasively determined PVR and had good accuracy with biases of <1 Wood units (WU), although with moderate precision and wide 95% limits of agreement varying from 5.9 to 7.8 Wood units. The ePVR models were accurate to within 1.9 WU in over 75% of patients. In comparison to the ePASP, ePVR models performed similarly in terms of correlation, accuracy, and precision when estimating invasive hemodynamics. In screening for pulmonary hypertension, ePVR models had equivalent testing characteristics to the ePASP. Mid‐systolic notching of the right ventricular outflow tract Doppler signal identified a subgroup of 11 patients (7%) with significantly elevated PVR and mean pulmonary artery pressures without relying on the acquisition of a tricuspid regurgitation signal. Analysis of ePVR and determination of the notching pattern of the right ventricular outflow tract Doppler flow velocity envelope provide reliable insights into hemodynamics in advanced lung disease patients, although limitations in precision exist.