bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perceptions of women enrolled in a cardiovascular disease screening and prevention in HIV study
Authors: Hanley Sherika , Ndlazi Galaletsang J. , Maddocks Stacy T. , Chetty Verusia 
Published: May 2023

Background: The ISCHeMiA (integration of cardiovascular disease screening and prevention in the human immunodeficiency virus [HIV] management plan for women of reproductive age) study is an ongoing, 3-year, prospective, quasi-experimental study comparing usual care to a primary health care intervention plan guided by the World Health Organization Package of Essential Non-Communicable (WHO-PEN) disease interventions. Sixty eight percent of women were overweight or obese at baseline in the ISCHeMiA study, many of whom reported nonadherence to interventions at 6 months post enrolment. This study explores the perceptions of women living with HIV (WHIV) towards their participation in the ISCHeMiA study to understand the barriers and facilitators to lifestyle modification interventions for cardiovascular disease (CVD) risk prevention.Methods: A qualitative enquiry using semistructured interviews was conducted with 30 overweight WHIV at one year post-enrolment in the WHO-PEN intervention arm of the ISCHeMiA study. Data were transcribed verbatim following the interviews and analysed using conventional content analysis.Results: Four major themes emerged from the data, namely perceived body image, benefits barriers and recommendations to improve adherence to WHO-PEN lifestyle modification management.Conclusion: Women in the ISCHeMiA study believed that HIV associated stigma hindered access to care. Financial limitations and the lack of social support posed barriers to adherence to programme participation. They were further challenged by poor body image perception. Participants believed that such interventions offered them hope and feelings of improved well-being. Women recommended that lifestyle modification interventions such as those studied in the ISCHeMiA study should include partners and family to improve adherence through social support.
Effect of HIV on mortality among hospitalised patients in South Africa
Authors: Lamprecht Dirk J. , Martinson Neil , Variava Ebrahim 
Published: May 2023

Background: HIV and AIDS continues to impose substantial healthcare challenges in sub-Saharan Africa, but there are limited local data comparing inpatient outcomes between people with HIV (PLWH) and those uninfected.Objectives: To compare cause-specific mortality among hospitalised adolescents and adults, stratified by HIV-serostatus.Method: A cross-sectional analysis was performed, analysing cause-specific inpatient mortality data and total admissions, from 01 January 2017 to 30 June 2020, at Tshepong Hospital, North West province, South Africa.Results: The overall inpatient mortality rate decreased from 14.5% (95% confidence interval [CI]: 13.4–16.0) in 2017, to 11.3% (95% CI: 10.6–11.9) in 2020; P 0.001. People living with HIV accounted for 53.9% (n = 2342) of inpatient deaths, 22.6% (n = 984) were HIV-seronegative patients and 23.5% (n = 1020) patients with unknown HIV-serostatus. People with HIV died at younger ages (median: 44 years, interquartile range [IQR]: 35.8–54.2) compared to HIV-seronegative inpatients (median: 64.4 years, IQR: 55.5–73.9); P 0.001. Leading causes of death were pneumonia (19.9%, n = 863), then pulmonary and extrapulmonary tuberculosis (15.0%, n = 654). People with HIV who had CD4+ counts 350 cells/mL or viral load ≥ 1000 copies/mL had increased risk of death from tuberculosis compared to virally suppressed patients (adjusted relative risk: 2.10 [95% CI: 1.44–3.04, P 0.009] and 1.56 [95% CI: 1.22–2.00, P 0.001]).Conclusion: Our study, conducted in a regional hospital in South Africa, showed PLWH had higher mortality rates and died at younger ages compared to HIV-seronegative patients.
Non-small-cell lung cancer and survivin −31G/C promoter polymorphism relation
Authors: Khalaf Asmaa R. , Foad Amira M. , Hemdan Shimaa B. , Nabil Emad E. , Esmaeel Hend M. 
Published: May 2023

Background
Lung cancer is known as one of the commonest cancers globally. It is considered an important cause of mortality all over the world. Survivin, a member of the family of inhibitor of apoptosis proteins, is involved in cell division regulation and apoptosis inhibition. The survivin gene is located on the human chromosome 17q25 and consists of 142 amino acids. Cancer risk was shown to be affected by the survivin promoter −31G/C genetic polymorphism. Such genetic variance was found to be associated with aberrant survivin expression in malignant cell at both protein and mRNA levels. One of the tumor suppressor gene is the p53 protein that induces cell apoptosis. Therefore, survivin polymorphism and p53 antibodies level association was considered in non-small-cell lung cancer (NSCLC).

Aim
To assess survivin promoter −31G/C polymorphisms in NSCLC, with detection of p53 antibodies level and the association between it and the gene polymorphism in those patients.

Patients and methods
In 2019–2020, a case–control designed research work was performed at Sohag University Hospital, Egypt. A total of 60 study participants were included in our study and categorized into 15 control group and 45 histopathologically confirmed NSCLC case group. The blood samples were collected into an EDTA tube and preserved frozen till DNA extraction.

Results
Our study shows a highly significant variation in the prevalence of the surviving gene promoter −31G/C polymorphism between cases and control groups (P<0.001). Moreover, regarding the level of p53 antibodies, it was higher in cases (17.01±5.97) than the control group (45.9±46.01), but the difference was not statistically significant (P=0.59). In our study, survivin −31G/C polymorphism was accompanied by epidermal growth factor receptor mutations detected in 33.3% of the cases, whereas 66.7% of the cases showed no mutation (wild type) of epidermal growth factor receptor.

Conclusion
Survivin promoter −31G/C gene polymorphism might have an association with lung cancer risk.
Predictors of extubation failure in mechanically ventilated patients with chronic obstructive pulmonary disease
Authors: Elkholy Maha M. , Sadek Samiaa H. , Elmorshedy Reham M. , Abdulmoez Marwa S. 
Published: May 2023

Background
Extubation failure is defined as the need for reinstitution of artificial airway within 48–72 h after planned extubation. It is associated with prolonged ICU and hospital stay and is more liable to serious complications and mortality.

Objectives
To evaluate the frequency of incidence and predictors of extubation failure in mechanically ventilated patients with chronic obstructive pulmonary disease (COPD) and its effect on their outcome.

Patients and methods
This observational descriptive cross-sectional study was carried out on 150 mechanically ventilated patients with COPD. All patients were assessed regarding the severity of the disease using both acute physiology and chronic health evaluation (APACHE) II and simplified acute physiology score scores and cough strength by white card test, with assessment of the amount of the secretion. All ventilatory parameters were monitored, with more attention given to the following: rapid shallow breathing index, negative inspiratory force (NIF), airway occlusion pressure, and weaning indices. Duration of sedation, complications, length of ICU stay, and also mortality rate were recorded.

Results
According to outcome of extubation, patients were classified into two basic groups: successfully extubated and failed extubation. Extubation failure occurred in 14.7% of the studied patients. Independent predictors of extubation failure were APACHE II more than 26, NIF less than −19, negative white card, CROP less than 11.5, large amount of secretions, and need for sedation more than 2 days. There were significant increases in the incidence of ventilator-associated pneumonia, mortality, ICU, and hospital stay among reintubated group.

Conclusion
APACHE II more than 26, NIF less than −19, negative white card, CROP less than 11.5, large amount of secretions, and need for sedation more than 2 days are good predictors of extubation failure in patients with COPD. Extubation failure is associated with more frequent morbidity and mortality.
Factors affecting survival in patients with lung cancer
Authors: Esmaeel Hend M. , Atta Kamal A. , Nabil Emad E. , Naom Mariam A. , Ali Abdellah H. 
Published: May 2023

Background
Lung cancer mortality is high all over the globe. A total of three million deaths are expected to be reached in 2035. There is a rising effort nationally for cancer data documentation and networking. This study is in line with this effort.

Purpose
This study aimed at assessment of the survival of patients with lung cancer in the regional locality and assessing factors affecting mortality in the studied population.

Patients and methods
This retrospective study included patients with lung cancer who were diagnosed and received treatment in the Oncology Department, Sohag University Hospital and Sohag Oncology Institute during the period from January 2016 to June 2019. The available data in patients’ records were collected, and it included medical history, clinical finding, diagnostic and metastatic workup, treatment, and follow-up for outcome.

Results
A total of 160 patients were enrolled in this study. Their median survival time was 1.21 year. Nonsmall-cell lung carcinoma, squamous subtype, showed higher 3-year survival (35.67%) than other histopathological subtype. Earlier tumor stage, stage II B, showed better survival than more advanced stages. Presence of positive local signs, current smoking status, and poorly differentiated tumor were significant risk factors for mortality in final multivariate analysis.

Conclusion
The study documented bad prognosis of lung cancer in our regional locality. It emphasized the worse prognosis for advanced stage of tumor and confirmed the role of smoking not only in development of lung cancer but also as mortality risk factor, which highlights the importance of smoking cessation programs to be initiated with focus on public awareness about it.
Placental expression of striatin & endothelial nitric oxide synthase in women with & without pre-eclampsia
Authors: Viveka M , Chaturvedula Latha , Ram Amit Kumar , Vairappan Balasubramaniyan 
Published: May 2023

Background & objectives:
Striatin is a multi-domain scaffolding protein essential for activating endothelial nitric oxide synthase (eNOS). However, its role in pre-eclampsia remains use explored. Hence, this study aimed to investigate the association between striatin and eNOS in regulating nitric oxide (NO) production in the placenta of women with and without pre-eclampsia.

Methods:
Forty pregnant women each without (controls) and with pre-eclampsia (cases) were enrolled in the study. Blood striatin and NO concentrations were detected by the ELISA. Protein expression of striatin, phosphorylated eNOS (peNOS), inducible NOS (iNOS) and phosphorylated NF-κB were measured in the placental tissues by Western blot. Twenty four hour urinary protein and serum urea, uric acid and creatinine were analyzed as an autoanalyzer. Placental histology was analyzed by haematoxylin and eosin staining.

Results:
Compared to normotensive pregnant women, the levels of serum NO and striatin were decreased in pre-eclamptic women. The protein expression of striatin and peNOS was significantly reduced (P<0.05) while p65NF-κB and iNOS were upregulated considerably (P<0.05) in the placenta of cases compared to controls.

Interpretation & conclusions:
Our results show for the first time that decreased striatin expression was associated with decreased peNOS protein expression in the placental tissue of pre-eclamptic women. Interestingly, no significant difference was found in blood striatin or NO levels between controls and cases. Thus, therapies that improve placental striatin expression are attractive possibilities, both for prevention as well as treatment of endothelial dysfunction in pre-eclampsia.
Impact of Lockdown and Psychological First Aid
Authors: Varma Ruchi , Yannawar Pravin B , Antony Reshma 
Published: May 2023

Introduction:
The COVID-19 pandemic and the subsequent lockdown declared by the Indian Government in March 2020 lead to an unexpected turn of events for many, causing a huge psychosocial impact on them.

Methodology:
The study focused on evaluating a family from Kerala with major language difficulties and the distress being faced by them during their stay in the government provided shelter home in Delhi. The family was assessed by the multidisciplinary team from the Institute of Human Behavior and Allied Sciences visiting various shelter homes across the state. The study was aimed to assess the importance of psychological first aid (PFA) on the individual and the family in distress.

Results:
The family was assessed by the student counselor, who was well versed in their native language Malayalam. They were able to connect well, and hence, an appropriate psychosocial intervention was provided to them under the guidance of her supervisor. The family was highly distressed and had almost developed xenophobia. They were very happy to get a Malayalam-speaking counselor and were provided with all possible support. The authorities were also explained about their specific needs, which was not possible earlier due to the language barrier. They were ultimately successfully integrated with the other residents and returned to their home state, i.e., Kerala.

Conclusion:
Although PFA is definitely not a substitute for mental health care, ample research and experience has shown that it is a useful tool to assist people in acute distress when applied with a truly professional yet sensitive, empathetic approach.
Analisis Kepuasan Penggunaan Aplikasi Classroom Pada Pembelajaran di Masa Pandemic Covid-19 menggunakan Metode Pieces
Authors: Cahyono Nur , Jaya Joy Nashar Utama 
Published: May 2023

During the current Covid-19 Pandemic, there are many changes that occur in the learning process, the use of online learning media is currently widely used by all students in Indonesia. Media Knowledge Management System (KMS) is a must in every online learning. Online learning media is very much an option, one of which is google classroom. Google classroom is one of the most popular and used learning media. This study aims to find out the application of the google classroom as a learning media during the covid-19 pandemic, to analyze and know the level of google classroom user satisfaction by student of SMK Muhammadiyah 1 Balikpapan Information System in the learning process. This research uses PIECES framework method consisting of Performance, Informations and data, Economics, Control and security, Efficiency and Service. The results of this study obtained the average value of each domain, namely the Performance domain got a value of 4.037 (Satisfied), Informations and data got a value of 3.995 (Satisfied), Economics got a value of 3.958 (Satisfied), Control and security got a value of 3.866 (Satisfied) , Efficiency got a value of 3.855 (Satisfied) and Service got a value of 3.868 (Satisfied). Meanwhile, the total average level of satisfaction from all domains is 3.929 (Satisfied).
A Review on the Natural Treatments of Allergic Rhinitis
Authors: Zhang Sissi , Cannata Angela 
Published: May 2023

Allergic rhinitis affects millions of people and can significantly lower an individual’s quality of life. The most common treatment for allergic rhinitis lies in over-the-counter medications. However, most over-the-counter antihistamines are either sedating, interfere with an individual’s life, and make them more prone to accidents or are non-sedating, but less researched. An increasing distrust of pharmaceuticals alongside the development of tolerance and even eventual withdrawal to treatment has made it necessary to evaluate other avenues of allergy treatment, including herbal medications.
An analysis of 9 clinical trials on three herbs, butterbur, astragalus membranaceus, and tinospora cordifolia, determined that the butterbur’s efficacy is the most well-established. Meanwhile, astragalus membranaceus features the most potential for success in treating allergies, but confidence within its clinical trials is also the lowest. These herbs are generally more cost effective and incur fewer side effects than current antihistamines, but more research is necessary to ensure the safety of their consumption.
The Interior Plan
Authors: Rengel Roberto J. 
Published: May 2023

The Interior Plan is an introductory-level text introducing students to the process of interior design space planning. Topics include the design of effective spatial sequences, functional relationships among project parts, arrangement of furniture, planning effective circulation systems, making spaces accessible, and designing safe environments with efficient emergency egress systems. Exercises throughout the book facilitate learning by encouraging students to apply ideas and concepts immediately after reading about them. In the third edition, the author expands on the evolution of design ideas and how they affect interior environments and the people who use them, thinking sustainably, and how interior elevations and reflective ceilings affect the plan.
New to This Edition
-New and updated examples in residential, commercial, retail, and hospitality planning
-New spreads addressing interior elevations, reflected ceiling plans, and interior planning for sustainability
-New pedagogical features in every chapter, including learning objectives, discussion questions, and key terms
Instructor Resources
-Instructor’s Guide provides suggestions for planning the course and using the text in the classroom, supplemental assignments, and lecture notes
-PowerPoint® presentations include images from the book and provide a framework for lecture and discussion
STUDIO Features Include:
-Download examples of common design pitfalls and how to avoid them
-Review concepts with flashcards of essential vocabulary and design strategies
Inventory of ectoparasites and molecular identification of pathogenic bacteria on bonylip barb (Osteochilus vittatus) cultivated in Banyumas District
Authors: Ekasanti Anandita , Syakuri Hamdan , Nugrayani Dewi , Listiowati Emyliana , Nurhafid Muhammad Nurhafid , Maulana Alvin 
Published: May 2023

The aims were to do an ectoparasite and pathogenic bacteria inventory of Bonylip barb reared in Banyumas district. Total of 118 fish were randomly taken from Singasari (30 individual), Pabuaran (30 individual), Beji (30 individual) and Jipang (28 individual) villages. This work observed ectoparasite species, prevalence, and intensity as well as pathogenic bacteria species. Ectoparasites were identified based on morphological characteristics observed microscopically and their prevalence and intensity were calculated. Bacterial pathogen was isolated from fish samples showing symptoms of bacterial disease and identified molecularly based on 16s rDNA sequence using BLAST dan phylogenetic analysis. Results showed Trichodina sp. and Monogeneans were found infected fish samples from all location with prevalence was 70-100%. Ichthyophthirius multifiliis was found from all location except Singasari village. Some of fish samples showed fin necrosis and five bacterial isolates were obtained. 16s rDNA marked gene was successfully amplified and sequenced. Based on sequence analysis, five isolates could be clustered into two groups, the first was found only in Singasari village and the second was found in Singasari and Beji villages. Similarity value of 16s rDNA gene sequence these two groups was 99,8%. Result of BLAST and phylogenetic analysis showed that the bacterial pathogens were identified as group of Aeromonas hydrophila complex.
Letter from the Editor
Authors: Au Scarlet , Oraedu Kairaluchi 
Published: May 2023

Dear Reader,
In 2023, the Columbia University Journal of Global Health continued to impact the Columbia campus community and beyond. Through leading discussions in public health and engaging with faculty across institutions, we strive to share research perspectives from around the world that confront the challenges of achieving equitable and accessible healthcare. We continue to celebrate the importance of research and the underlying rigor of the scientific process. We are excited to share our newest Spring 2023 issue with our readers.
Our community engagement efforts in New York resulted in multiple collaborations with Columbia University Mailman School of Public Health faculty and the New York City Fire Department, which has engaged the Columbia University student body in relevant and timely global health topics. We distributed fentanyl testing kits and partnered with the New York City Fire Department for a CPR training event to educate students with useful skills in addressing health emergencies. In February, we hosted a panel discussion titled “Black Professionals in Public Health”, which featured guest speakers Dr. Paris Adkins-Jackson–Assistant Professor at the Columbia Department of Epidemiology and Sociomedical Sciences–and Dr. Kiros Berhane–Chairman of Biostatistics at the Columbia Mailman School of Public Health. Adkins-Jackson and Berhane addressed how they designed research studies to investigate racial disparities in access to care and navigated public health and academia from a personal perspective.
In recognizing the importance of having accessible and open scientific communication between the scientific community and the general public, our “What is Global Health?” podcast and blog has served as an active online platform to foster discussions with Columbia faculty. Our recent blog posts share perspectives on topics from women’s menstrual health to global hunger. The newest episode of the podcast features a discussion on utilizing data science to inform public health with Dr. Mary Beth Terry from Columbia University’s Mailman School of Public Health.
This Spring 2023 issue explores public health topics including a novel community participatory approach to violence intervention programs for Latino youth, challenges in accessing maternity care for immigrants and medical interpretation. We would like to express our gratitude towards our journal team, faculty advisors Esther Jackson and Professor James Colgrove, authors and peer reviewers for their submissions and contributions without which our journal could not exist.
Sincerely,Scarlet Au & Kairaluchi OraeduCo-Editors-in-Chief, The Columbia University Journal of Global Health
Microanalysis of E-Money Transfer Services through E-Servqual Approach: A Basis for Enhanced Customer Satisfaction Strategy
Authors: Santillan Cyrene Joy P. , Mendoza Xavier Lawrence D. , Tadeo Jerico B. 
Published: May 2023

Adopting various technologies in enterprises was vital since it provided a quick service process. E-money transfer services study aimed to evaluate customer satisfaction with e-money transfer services using E-SERVQUAL Approach. The researchers used a descriptive-correlational research design and purposive sampling to select 100 e-money transfer service customers in selected Cavite municipalities. The study's results revealed that the participants were primarily young adult females, commonly single. The results showed that most participants were college undergraduates with a monthly income of Php 10,000 and below. The study showed that the customers were highly satisfied with e-money transfer services regarding reliability, security, website design, accessibility, and personalization. In contrast, in terms of responsiveness, the customers were satisfied. The study found that the biggest challenges in utilizing e-money transfer services were lack of prompt responses, slow money processing, the possibility of committing fraud, lack of creativity of the website, not an accessible website, and lack of expertise. This study showcased that the age of customers has a significant difference to the reliability of e-money transfer services. This study recommended that e-money transfer services improve the e-service quality for customer satisfaction.
Keywords: E-money transfer services, customer satisfaction, online services, E-SERVQUAL