bluuebunny/crossref_metadata_2025_split huggingface dataset:
The carcinogenicity of opium consumption: a systematic review and meta-analysis
Authors: M. Filho Adalberto , Turner Michelle C. , Warnakulasuriya Saman , Richardson David B. , Hosseini Bayan , Kamangar Farin , Pourshams Akram , Sewram Vikash , Cronin-Fenton Deirdre , Etemadi Arash , Glass Deborah C. , Rahimi-Movaghar Afarin , Sheikh Mahdi , Malekzadeh Reza , Schubauer-Berigan Mary K. 
Published: February 2023

AbstractThe carcinogenicity of opium consumption was recently evaluated by a Working Group convened by the International Agency for Research on Cancer (IARC). We supplement the recent IARC evaluation by conducting an extended systematic review as well as a quantitative meta-analytic assessment of the role of opium consumption and risk for selected cancers, evaluating in detail various aspects of study quality on meta-analytic findings. We searched the published literature to identify all relevant studies on opium consumption and risk of selected cancers in humans through 31 October, 2022. Meta-relative risks (mRRs) and associated 95% confidence intervals (CIs) were estimated using random-effects models for studies of cancer of the urinary bladder, larynx, lung, oesophagus, pancreas, and stomach. Heterogeneity among studies was assessed using the I2 statistic. We assessed study quality and conducted sensitivity analyses to evaluate the impact of potential reverse causation, protopathic bias, selection bias, information bias, and confounding.
In total, 2 prospective cohort studies and 33 case–control studies were included. The overall pooled mRR estimated for ‘ever or regular’ versus ‘never’ use of opium ranged from 1.50 (95% CI 1.13–1.99, I2 = 0%, 6 studies) for oesophageal cancer to 7.97 (95% CI 4.79–13.3, I2 = 62%, 7 studies) for laryngeal cancer. Analyses of cumulative opium exposure suggested greater risk of cancer associated with higher opium consumption. Findings were robust in sensitivity analyses excluding studies prone to potential methodological sources of biases and confounding. Findings support an adverse association between opium consumption and cancers of the urinary bladder, larynx, lung, oesophagus, pancreas and stomach.
Phosphorus sustainability through coordinated stakeholder engagement: a perspective
Authors: Deviney Alison , Grieger Khara , Merck Ashton , Classen John , Marshall Anna-Maria 
Published: February 2023

AbstractIn this Perspective we take an in-depth look at what coordinated stakeholder engagement could entail for phosphorus sustainability. The element phosphorus is critical to life on Earth and to the continued functioning of society as we know it. Yet, how society uses phosphorus is currently unsustainable, both as a resource in support of global food production where inequitable distribution creates food security challenges, but also from an environmental aspect, where mismanagement has led to negative impacts on the quality of agricultural soils, human health, and freshwater and marine ecosystems. A number of initiatives and cross-sector consortia have come together to address sustainable phosphorus management at either global or regional scales. However, these efforts could benefit from a more coordinated approach to stakeholder engagement to identify the diversity of needs and perspectives involved in this complex challenge. Herein we examine some examples of different approaches to developing such coordinated stakeholder engagement in other areas of environmental sustainability. We consider how to apply the lessons learned from those efforts toward stakeholder coordination in the realm of phosphorus sustainability. Particularly, we discuss the value of a coordinating body to manage the communications and knowledge sharing necessary to develop trust and cooperation among diverse stakeholder groups and to transition society to more sustainable phosphorus use.
Measuring scientific reasoning in kindergarten and elementary school: validating the Chinese version of the Science-K Inventory
Authors: Osterhaus Christopher , Lin Xiya , Koerber Susanne 
Published: February 2023

AbstractScientific reasoning is a twenty-first century skill that is important for economic growth and social prosperity. A growing body of research documents that basic scientific reasoning skills develop much earlier than initially assumed, with many young elementary school and even kindergarten-aged children showing emergent scientific reasoning skills. Many studies on early scientific reasoning have been conducted in Western countries, and there is a lack of validated instruments that can be used in cross-cultural work. The present paper reports on the findings of a study assessing the psychometric properties of the shortened Chinese version of the Science-K(indergarten) Inventory (SC-SKI). The SC-SKI consists of 10 items that assess children’s understanding of the nature of science, as well as their experimentation and data interpretation skills. Sixty-nine 6- to 7-year-olds from urban and rural schools in the Hunan province (China) participated in the study. The results showed an acceptable reliability of the SC-SKI (McDonald’s ωt = 0.60). The ability estimates obtained for children’s scientific reasoning (average performance was 47.5% correct) were comparable to those measured in German 6-year-olds (45.1% correct), and the urban sample outperformed the rural sample, supporting the ability of the SC-SKI to detect expected performance differences in young children’s scientific reasoning. A significant correlation between scientific reasoning and language skills (r = 0.54, p < 0.05) confirms earlier findings and indicates construct validity. Taken together, the present study shows that the SC-SKI is a reliable and valid instrument that can be used to measure scientific reasoning in Chinese-speaking 6- to 7-year-olds.
The Village, the Elephant, and the State: Land Access and Vulnerability in Rural Botswana
Authors: Redmore Lauren , Katholo Ipolokeng , Sene-Harper Aby , Songhurst Anna , McCulloch Graham , Stronza Amanda 
Published: February 2023

Abstract
Throughout the world, people resettle to reduce vulnerability to potentially dangerous wildlife, including elephants. In turn, they may become subject to development policies and practices that can either exacerbate or alleviate their vulnerability. Our ethnographic study in the Okavango Delta of Botswana, where 18,000 elephants share territory with 16,000 people, examines how resettlement decisions and settlement policies impacted vulnerability to elephants. We found that people who came into regular conflict with elephants frequently relocated from cattleposts to villages. Although people historically resettled near family, in 2015 a newly introduced “first-come, first-served” residential plot allocation policy spatially separated families within the village, creating further vulnerability for households relying on kinship networks. We found that government planning that incorporates locally available strategies, such as the ability to access support from kinship networks, may reduce vulnerability for those forced to resettle by elephant encroachment on their land.
Bioactive fraction from Plumeria obtusa L. attenuates LPS-induced acute lung injury in mice and inflammation in RAW 264.7 macrophages: LC/QToF-MS and molecular docking
Authors: Eloutify Yousra T. , El-Shiekh Riham A. , Ibrahim Khaled Meselhy , Hamed Ahmed R. , Al-Karmalawy Ahmed A. , Shokry Aya A. , Ahmed Yasmine H. , Avula Bharathi , Katragunta Kumar , Khan Ikhlas A. , Meselhy Meselhy R. 
Published: February 2023

AbstractIn this study, the anti-inflammatory effects of the methanolic extract (TE) of Plumeria obtusa L. (aerial parts) and its fractions were evaluated in vitro, and active fraction was evaluated in vivo. Among tested extracts, dichloromethane fraction (DCM-F) exhibited the strongest inhibition of lipopolysaccharide (LPS)-induced nitric oxide (NO) in RAW 264.7 macrophages. The effect of DCM-F on LPS-induced acute lung injury (ALI) in mice was studied. The animals were divided into five groups (n = 7) randomly; Gp I: negative control, GP II: positive control (LPS group), GP III: standard (dexamethasone, 2 mg/kg b.wt), GP IV and V: DCM-F (100 mg/kg), and DEM-F (200 mg/kg), respectively. DCM-F at a dose of 200 mg/kg suppressed the ability of LPS to increase the levels of nitric oxide synthase (iNOS), NO, tumor necrosis factor-α (TNF-α), and interleukin 6 (IL-6), as measured by ELISA. In addition, the expression of cyclooxygenase-2 (COX-2) was reduced (determined by immunohistochemistry) and the level of malondialdehyde (MDA) was decreased while that of catalase was restored to the normal values. Furthermore, the histopathological scores of inflammation induced by LPS were reduced. Twenty-two compounds were tentatively identified in DCM-F using LC/ESI-QToF with iridoids, phenolic derivatives and flavonoids as major constituents. Identified compounds were subjected to two different molecular docking processes against iNOS and prostaglandin E synthase-1 target receptors. Notably, protoplumericin A and 13-O-coumaroyl plumeride were the most promising members compared to the co-crystallized inhibitor in each case. These findings suggested that DCM-F attenuates the LPS-induced ALI in experimental animals through its anti-inflammatory and antioxidant potential.
Color tuneability behaviour and energy transfer analysis on Dy3+-Eu3+ co-doped glasses for NUV-WLEDs application
Authors: Monisha M. , Sayyed M. I. , Mazumder Nirmal , Arayro Jack , Kamath Sudha D. 
Published: February 2023

AbstractA series of Dy3+ and Eu3+ co-doped zinc aluminoborosilicate (ZABS) glasses were synthesized by a high-temperature melt-quenching method. Visible and NIR transitions of Dy3+-Eu3+ ions are observed through absorption spectra. A reverse trend in the optical band gap values and Urbach energy are seen with addition of Eu3+ ions. Photoluminescence studies recorded under different excitation wavelengths showed a variation in the emission intensities and prevailed the color tuneability behaviour of dopants. The energy transfer between Dy3+ and Eu3+ ions are studied through emission profiles, energy level diagram, and decay curves. The type of multipolar interaction between Dy3+ and Eu3+ are understood via Inokuti-Hirayama (IH) model and Dexter energy model. The CIE chromaticity coordinates, and correlated color temperature (CCT) values suggest that the prepared glasses can be used for light emitting diode application when excited at near-ultraviolet region.
The Role of Attachment Styles on Quality of Life and Distress Among Early-Stage Female Breast Cancer Patients: A Systematic Review
Authors: Karveli Spyridoula , Galanis Petros , Mitropoulou Eirini Marina , Karademas Evangelos , Markopoulos Christos 
Published: February 2023

AbstractCancer patients’ quality of life (QoL) and distress are affected by dispositional factors such as attachment anxiety or avoidance. In this review, we aimed to provide a thorough overview of the relationship between attachment dimensions and QoL and distress among early-stage breast cancer patients. Following PRISMA guidelines, we conducted a systematic search using PubMed, PsycINFO, Scopus, Cinahl, Google Scholar, and PMC Europe. We reviewed 8 eligible studies describing 1180 patients. Insecure attachment appeared to be related to poorer QoL and higher distress levels. Avoidant attachment was more frequent and was more often associated with more negative outcomes. Healthcare providers should consider investigating modifiable personality traits in the immediate post diagnosis period to identify patients more vulnerable to mental health problems, deliver personalized care, and reduce emotional burden.
Hydrogen Sulphide-Based Therapeutics for Neurological Conditions: Perspectives and Challenges
Authors: Sharif Amir H. , Iqbal Mohammed , Manhoosh Bahareh , Gholampoor Negin , Ma Dan , Marwah Mandeep , Sanchez-Aranguren Lissette 
Published: February 2023

AbstractCentral nervous system (CNS)-related conditions are currently the leading cause of disability worldwide, posing a significant burden to health systems, individuals and their families. Although the molecular mechanisms implicated in these disorders may be varied, neurological conditions have been increasingly associated with inflammation and/or impaired oxidative response leading to further neural cell damages. Therefore, therapeutic approaches targeting these defective molecular mechanisms have been vastly explored. Hydrogen sulphide (H2S) has emerged as a modulator of both inflammation and oxidative stress with a neuroprotective role, therefore, has gained interest in the treatment of neurological disorders. H2S, produced by endogenous sources, is maintained at low levels in the CNS. However, defects in the biosynthetic and catabolic routes for H2S metabolism have been identified in CNS-related disorders. Approaches to restore H2S availability using H2S-donating compounds have been recently explored in many models of neurological conditions. Nonetheless, we still need to elucidate the potential for these compounds not only to ameliorate defective biological routes, but also to better comprehend the implications on H2S delivery, dosage regimes and feasibility to successfully target CNS tissues. Here, we highlight the molecular mechanisms of H2S-dependent restoration of neurological functions in different models of CNS disease whilst summarising current administration approaches for these H2S-based compounds. We also address existing barriers in H2S donor delivery by showcasing current advances in mediating these constrains through novel biomaterial-based carriers for H2S donors.
Dynamics of a mechanical system with a spherical pendulum subjected to fractional damping: analytical analysis
Authors: Freundlich Jan , Sado Danuta 
Published: February 2023

AbstractIn the paper, nonlinear vibrations of a system with three degrees of freedom having a spherical pendulum are considered. The system comprises a mass element suspended from a linear spring and a viscous damper, and a spherical pendulum swung from the mass element. It is assumed that the fractional viscous damping occurs in the viscous damper and at the pendulum pivot point. The viscoelastic properties of damping are assumed to be described using the Riemann–Liouville fractional derivative. The fractional derivative of an order of $$ 0 < \alpha \le 1$$

0
<
α
≤
1

is assumed. The nonlinear vibrations of the system near internal and external resonances are analyzed. The equations of motion of the analyzed system are solved using the multiple-scale method. The steady-state approximate solution is studied. The effect of a fractional-order derivative on the system vibrations is examined.
Pharmacists’ clinical roles and activities in inpatient hospice and palliative care: a scoping review
Authors: Wernli Ursina , Hischier Désirée , Meier Christoph R. , Jean-Petit-Matile Sibylle , Kobleder Andrea , Meyer-Massetti Carla 
Published: February 2023

Abstract
Background
Pharmacists contribute to medication safety by providing their services in various settings. However, standardized definitions of the role of pharmacists in hospice and palliative care (HPC) are lacking.

Aim
The purpose of this scoping review was to provide an overview of the evidence on the role of pharmacists and to map clinical activities in inpatient HPC.

Method
We performed a scoping review according to the PRISMA-ScR extension in CINAHL, Embase, and PubMed. We used the American Society of Hospital Pharmacists (ASHP) Guidelines on the Pharmacist’s Role in Palliative and Hospice Care as a framework for standardized categorization of the identified roles and clinical activities.

Results
After screening 635 records (published after January 1st, 2000), the scoping review yielded 23 publications reporting various pharmacy services in HPC. The articles addressed the five main categories in the following descending order: ‘Medication order review and reconciliation’, ‘Medication counseling, education and training’, ‘Administrative Roles’, ‘Direct patient care’, and ‘Education and scholarship’. A total of 172 entries were mapped to the subcategories that were added to the main categories.

Conclusion
This scoping review identified a variety of pharmacists’ roles and clinical activities. The gathered evidence will help to establish and define the role of pharmacists in inpatient hospice and palliative care.
Plant-soil feedback: incorporating untested influential drivers and reconciling terminology
Authors: De Long Jonathan R. , Heinen Robin , Heinze Johannes , Morriën Elly , Png G. Kenny , Sapsford Sarah J. , Teste François P. , Fry Ellen L. 
Published: February 2023

Abstract
Background
Plants condition the soil in which they grow, thereby altering the performance of subsequent plants growing in this soil. This phenomenon, known as plant-soil feedback (PSF), has garnered increasing interest. Experiments are moving from single species soil pairings in the glasshouse to community-level field trials. Consequently, our knowledge of the role PSF plays in shaping ecosystem functions has advanced. However, knowledge gaps remain.

Scope
Here, we explore intrinsic and extrinsic abiotic and biotic drivers of PSF such as maternal effects, plant functional traits, self-DNA, plant-plant competition, herbivory, interactions between soil organisms, temperature, drought, flooding, greenhouse gases, (micro)nutrients, plant-litter-soil feedback and priority effects. These drivers have begun to feature in experiments, thereby increasing our mechanistic understanding of PSF. Nonetheless, many of these topics have received insufficient coverage to determine general principles across larger temporal and spatial scales. Further, conflicting terminology has excluded PSF studies from reviews and meta-analyses. We review terms such as soil sickness, Janzen-Connell hypothesis, soil-related invasive species work, soil legacies, allelopathy and soil-related succession that overlap with PSF but are generally not named as such.

Conclusion
Holistic experimental designs that consider the continual reciprocal feedback between the extrinsic environment, plants and soil, as well as the unification of terminologies are necessary if we are to realise the full potential of PSF for understanding and steering ecosystem processes. Here, we compile outstanding questions related to PSF research that emphasis the aforementioned topics and suggest ways to incorporate them into future research in order to advance plant-soil ecology.
Impact of the number and rank of coauthors on h-index and π-index. The part-impact method
Authors: Vinkler Péter 
Published: February 2023

AbstractThe publication activity of 20 Price-medallists was analysed by calculating several scientometric indices from data of elite sets of their publications. The following elite sets (i.e. most cited papers within the total) were obtained:π-set (where the number of papers is equal to √P, andPis the number of total papers),h-set (in which the number of papers equals to the Hirsch index), 2π-set, 2h-set, and the set of papers (ECP) which are cited more frequently than the average. The percentage share of papers and citations was found to increase in the mentioned rank of the elite sets, except ECP-set. The number of publications and citations in the elite sets was calculated also by different part-impact methods forsharing credit among the coauthors.The applied methods take into account the number or number and rank of coauthors in the by-line of the papers. It was demostrated that any of the methods changes bothπandh-index significantly related to the value calculated by attributing total credit to the evaluated individual. The changes strongly depend on the number of coauthors and rank of the studied author in the by-line of the papers. Consequently, in assessing personal contribution of scientists by scientometric indices, sharing credit of publications and citations among the coauthors of publications seems to be highly relevant. Selecting the appropriate impact sharing method depends on the purpose of the evaluation.
Empirical relationship between the number of review and research articles
Authors: Praus Petr 
Published: February 2023

AbstractIn this contribution, an empirical relationship between the number of review and research articles published per year was searched. The simple idea based on proportionality (linearity) between the numbers of both kinds of articles was expressed in terms of a quadratic relationship, in which the quadratic member can reflect negative or positive deviations from the assumed linearity. The quadratic relationship was able to describe beginning periods of research fields as well as their mature phases and to detect the unpredictably high number of review articles. It was verified by the articles published in 20 various research fields taken from the Web of Science during different time spans.
Novel inducible promoter DREB1G cloned from date palm exhibits high fold expression over AtRD29 to drought and salinity stress
Authors: Kodackattumannil Preshobha , Whitley Kenna , Sasi Shina , Lekshmi Geetha , Krishnan Saranya , Al Senaani Salima , Kottackal Martin , Amiri Khaled M. A. 
Published: February 2023

AbstractRight and timely expression of the stress regulatory genes is required for plants to compete against abiotic stresses; it necessitates the isolation and characterization of stress-responsive promoters for improving crops' tolerance to abiotic stresses. Dehydration Responsive Element Binding (DREB) regulates the expression of numerous stress-responsive genes in plants and leads an inevitable role in the adaptation of plants to abiotic stresses. In this study, the promoter region of Phoenix dactylifera (Date palm, a major fruit crop of the arid region) PdDREB1G gene was isolated and characterized for the first time. A comparison of the activity of two promoter fragments, 880 bp (DS) and 1.6 kb (DF) of PdDREB1G to AtRD29A was performed. Histochemical assay displayed remarkable GUS staining and RT-qPCR analysis confirmed the induction of GUS expression in T3 plants of transformed tobacco subjected to different abiotic stresses. Furthermore, compared with the widely used AtRD29A promoter, the relative expression of GUS in leaves by DS and DF was three and twofold higher under salt stress, respectively, while it was twofold in polyethylene glycol (PEG) and abscisic acid (ABA) for DS. Under SA stress, DF and DS displayed 1.5 and onefold expression in leaves, respectively. In the root, DS showed a fourfold increased expression in salt, threefold in PEG and ABA, and twofold in SA. Hence, the DS promoter characterized in the present study becomes a choice over RD29A for abiotic stress responses and is useful to develop stress-tolerant transgenic plants by inducing the expression of stress-inducible genes on stress.