bluuebunny/crossref_metadata_2025_split huggingface dataset:
First evidence for non 1− pygmy dipole resonance in neutron-rich nuclei
Authors: Li R. , Ponomarev V. Yu. , Harakeh M. N. , Ayoubi L. , Falou H. Al , Benzoni Giovanna , Blanc F. , Bozkurt V. , Ciemala Michal , Delafosse Clement , Deloncle I. , Didierjean F. , Ebata S. , Fallot M. , Gaulard C. , Gottardo Andrea , Guadilla V. , Guillot J. , Hadyńska-Kl˛ek K. , Ibrahim F. , Jovancevic Nikola , Kankainen Anu , Lebois Mathieu , Matea I. , Napiorkowski P. , Roussiere B. , Sobolev Yu. , Stefan I. , Stukalov S. , Thisse D. , Tocabens G. , Verney D. 
Published: August 2023

Abstract
We predict the existence of medium spin PDR and find experimental evidence in 80Ge using β-decay of 80Ga. This nucleus was produced in the photo-fission of 238U. A hybrid γ-ray spectrometer was developed using a plastic detector for β-tagging, HPGe detectors for low-energy γ rays detection and phoswich detectors of PARIS for high-energy γ rays. The low-high energy coincidence spectrum shows two peaks at 7181(53) and 7337(53) keV in the β-decay of the 80mGa isomeric state only, in coincidence with the 21+ → 0+ transition of 80Ge. Combined with decay information, electric dipole character (E1) were assigned to these γ rays which de-excite 7.84 MeV and 7.996 MeV states. Based on this fact and the comparison with theoretical calculations, we conclude that these enhanced E1 transitions are driven by neutron-skin oscillation of 80Ge. The oscillation is triggered by a conversion of a deeply-bound neutron from the Z=N=28 proton-neutron saturated core into a proton in the Fermi surface. These results provide an evidence for a PDR state with spin different from 1− and built on a low-energy excited state. Consequently, it extends the PDR’s boundary along spin dimension for the first time and provides experimental data for testing the validity of the Brink-Axel hypothesis in the PDR region.
Interventions to increase vaccination in vulnerable groups: rapid overview of reviews
Authors: Norman Gill , Kletter Maartje , Dumville Jo 
Published: August 2023

Abstract
Objective
Groups which are marginalised, disadvantaged or otherwise vulnerable have lower uptake of vaccinations. This differential has been amplified in COVID-19 vaccination compared to (e.g.) influenza vaccination. This overview assessed the effectiveness of interventions to increase vaccination in underserved, minority or vulnerable groups.
Methods
In November 2022 we searched four databases for systematic reviews including RCTs of interventions to increase vaccination in underserved, minority or vulnerable groups. We used rapid review methods to screen, extract data and assess risk of bias in identified reviews. We undertook narrative synthesis using an approach modified from SWiM guidance. We categorised interventions as being high, medium or low intensity, and as targeting vaccine demand, access, or providers.
Results
We included 23 systematic reviews, including studies in high and low or middle income countries, focused on children, adolescents and adults. Groups were vulnerable based on socioeconomic status, minority ethnicity, migrant/refugee status, age, location or LGBTQ identity. Pregnancy/maternity sometimes intersected with vulnerabilities. Evidence supported interventions including: home visits to communicate/educate and to vaccinate, and facilitator visits to practices (high intensity); telephone calls to communicate/educate, remind/book appointments (medium intensity); letters, postcards or text messages to communicate/educate, remind/book appointments and reminder/recall interventions for practices (low intensity). Many studies used multiple interventions or components.
Conclusion
There was considerable evidence supporting the effectiveness of communication in person, by phone or in writing to increase vaccination. Both high and low intensity interventions targeting providers showed effectiveness. Limited evidence assessed additional clinics or targeted services for increasing access; only home visits had higher confidence evidence showing effectiveness. There was no evidence for interventions for some communities, such as religious minorities which may intersect with gaps in evidence for additional services. None of the evidence related to COVID-19 vaccination where inequalities of outcome are exacerbated.
Prospero registration: CRD42021293355
The Effect of Cuff Arthropathy Stage on Sleep Disturbance and Kinesiophobia in Reverse Shoulder Arthroplasty Patients
Authors: ILYAS Gokhan , EGELI Ercument , IPCI Fikri Burak , GOKALP Oguzhan 
Published: August 2023

Abstract
Background
The aim of the current study was to determine the changes in pre-and postoperative Pittsburg sleep quality index (PSQI) and Tampa scale of kinesiophobia (TSK) values ​​according to the Hamada classification in patients who underwent reverse shoulder arthroplasty (RSA) for rotator cuff tear arthropathy (RCTA).
Methods
One hundred and eight patients who underwent RSA for RCTA were reviewed retrospectively. The patients were divided into two groups with low grade (stages 1-2-3) (n = 49) and high grade (stages 4a-4b-5) (n = 59) according to the Hamada classification, which is the radiographic evaluation of RCTA. PSQI and TSK values ​​were calculated preoperatively, and post-operatively at the 6th week, 6th month, and 1st year. The change in PSQI and TSK values ​​between the evaluations and the effect of staging according to the Hamada classification on this change was examined.
Results
When compared in preoperative evaluations, PSQI and TSK scores were found to be lower in low-grade group 1 (7.39 ± 1.56, 51.88 ± 4.62, respectively) than in high-grade group 2 (10.47 ± 2.39, 57.05 ± 3.25, respectively) according to Hamada classification (both p < 0.001). In the postoperative evaluations, PSQI and TSK results decreased gradually compared to the preoperative evaluations, and there was a dramatic decrease in both parameters between the 6th-week and 6th-month evaluations (both p < 0.001). Preoperatively, 102 (95%) patients had sleep disturbance (PSQI ≥ 6), and 108 (100%) patients had high kinesiophobia (TSK > 37). In the 1st year follow-ups, sleep disturbance was observed in 5 (5%) patients and kinesiophobia in 1 (1%) patient. When the Hamada stages were compared, it was seen that there was a significant difference before the operation (both p < 0.001), but the statistically significant difference disappeared in the PSQI value in the 1st year (p = 0.092) and in the TSK value in the 6th month (p = 0.164) post-operatively. It was observed that Hamada staging caused significant differences in PSQI and TSK values ​​in the preoperative period but did not affect the clinical results after treatment.
Conclusions
RSA performed based on RCTA improves sleep quality and reduces kinesiophobia. RCTA stage negatively affects PSQI and TSK before the operation but does not show any effect after the treatment.
A methodology for multiple performances optimization of computer numerical controlled (CNC) machining process based on design of experiment, multi-criteria decision-making and multiple regression model
Authors: Ryang Si-Ho , Yang Won-Chol , Kuon Chang-Hyok , Kim Chol-Sok , Kim Yong-Il 
Published: August 2023

Abstract
This paper proposes multiple performances optimization methodology for computer numerical controlled (CNC) machining based on Taguchi method, multi-criteria decision making (MCDM) and multiple regression (MR) model. It consists of the following steps: (1) setting levels of process parameters and selecting appropriate orthogonal array (OA), (2) arranging the parameters on OA and measuring machining performance values at every trials, (3) calculating comprehensive performance (CP) by integrating the multiple performances using a reasonable MCDM, (4) developing MR model between CP and process parameters, (5) analyzing influence of process parameters using correlation analysis and Taguchi method, and (6) determining optimal process parameters using Taguchi and grid search methods. The methodology is applied to determine optimal turning process parameters for optimizing multiple machining performances in the high speed CNC turning of AISI P20 tool steel. It may be widely applicable to solve many practical multiple performances optimization problems in manufacturing.
Impact of KRAS Mutations and Co-mutations on Clinical Outcome in Pancreatic Ductal Adenocarcinoma
Authors: Zhao Dan , Yousef Abdelrahman , Yousef Mahmoud , Chowdhury Saikat , Abdilleh Kawther , Knafl Mark , Edelkamp Paul , Alfaro-Munoz Kristin , Chacko Ray , Peterson Jennifer , Smaglo Brandon , Wolff Robert A. Wolff , Pant Shubham , Lee Michael , Willis Jason , Overman Michael , Doss Sudheer , Matrisian Lynn , Hurd Mark , Snyder Rebecca , Katz Matthew , Wang Huamin , Maitra Anirban , Shen John Paul 
Published: August 2023

Abstract
The relevance of KRAS mutation alleles to clinical outcome remains inconclusive in pancreatic adenocarcinoma (PDAC). We conducted a retrospective study of 803 PDAC patients (42% with metastatic disease) at MD Anderson Cancer Center. Overall survival (OS) analysis demonstrated that KRAS mutation status and subtypes were prognostic (p<0.001). Relative to patients with KRAS wildtype tumors (median OS 38 months), patients with KRASG12R had a similar OS (median 34 months), while patients with KRASQ61 and KRASG12D mutated tumors had shorter OS (median 20 months [HR: 1.9, 95% CI 1.2-3.0, p=0.006] and 22 months [HR: 1.7, 95% CI 1.3-2.3, p<0.001], respectively). There was enrichment of KRASG12D mutation in metastatic tumors (34% vs 24%, OR: 1.7, 95% CI 1.2-2.4, p=0.001) and enrichment of KRASG12R in well and moderately differentiated tumors (14% vs 9%, OR: 1.7, 95% CI 1.05-2.99, p=0.04). Similar findings were observed in the external validation cohort (PanCAN’s Know Your Tumor® dataset, n=408).
Ethnicity-specific BRCA1, BRCA2, PALB2, and ATM pathogenic alleles in breast and ovarian cancer patients from the North Caucasus
Authors: Sokolenko Anna P. , Bakaeva Elvina Kh. , Venina Aigul R. , Kuligina Ekaterina Sh. , Romanko Alexandr A. , Aleksakhina Svetlana N. , Belysheva Yana V. , Belogubova Evgeniya V. , Stepanov Ilya A. , Zaitseva Olga A. , Yatsuk Olga S. , Togo Alexandr V. , Khamgokov Zaur M. , Kadyrova Azinat O. , Pirmagomedov Albert Sh. , Bolieva Marina B. , Epkhiev Alexandr A. , Tsutsaev Aslan K. , Chakhieva Madina D. , Khabrieva Khalimat M. , Khabriev Idris M. , Murachuev Mirza A. , Buttaeva Bella N. , Baboshkina Liliya S. , Bayramkulova Fatima I. , Katchiev Islam R. , Alieva Lina Kh. , Raskin Grigory A. , Orlov Sergey V. , Khachmamuk Zarema K. , Levonyan Karine R. , Gichko Dariya M. , Kirtbaya Dmitriy V. , Degtyariov Alexey M. , Sultanova Luisa V. , Musayeva Hedi S. , Belyaev Alexey M. , Imyanitov Evgeny N. 
Published: August 2023

Abstract
Background
Mountain areas of the North Caucasus host several large ethnic communities that preserved their national identity over the centuries.
Methods
This study involved high-grade serous ovarian cancer (HGSOC) and breast cancer (BC) patients from Dagestan (HGSOC: 37; BC: 198), Kabardino-Balkaria (HGSOC: 68; BC: 155), North Ossetia (HGSOC: 51; BC: 104), Chechnya (HGSOC: 68; BC: 79), Ingushetia (HGSOC: 19; BC: 103), Karachay-Cherkessia (HGSOC: 13; BC: 47), and several Armenian settlements (HGSOC: 16; BC: 101). The group of BC patients was enriched by young-onset and/or family history-positive and/or bilateral and/or receptor triple-negative cases. The entire coding region of BRCA1, BRCA2, PALB2, and ATM genes was analyzed by next-generation sequencing.
Results
A significant contribution of BRCA1/2 pathogenic variants (PVs) in HGSOC and BC development was observed across all North Caucasus regions (HGSOC: 18.8–38.5%; BC: 6.3–13%). Founder alleles were identified in all ethnic groups studied, e.g., BRCA1 c.3629_3630delAG in Chechens, BRCA2 c.6341delC in North Ossetians, BRCA2 c.5351dupA in Ingush, BRCA1c.2907_2910delTAAA in Karachays, etc. Some BRCA1/2alleles, particularly BRCA2c.9895C>T, were shared by several nationalities. ATM PVs were detected in 14 patients, with c.1673delG and c.8876_8879delACTG alleles occurring twice each. PALB2 heterozygosity was observed in 5 subjects, with one variant seen in 2 unrelated women.
Conclusion
This study adds to the evidence for the global-wide contribution of BRCA1/2 genes to BC and HGSOC morbidity, although the spectrum of their PVs is a subject of ethnicity-specific variations. The data on founder BRCA1/2alleles may be considered when adjusting the BRCA1/2 testing procedure to the ethnic origin of patients.
Exploring the Impact of COVID-19 Information Acquisition on University Students' Psychological Capital: The Mediating Roles of Risk Perception and Emotional Coping in a Chain Model
Authors: Han Bingxu 
Published: August 2023

Abstract
Background
University students in the 2022 Shanghai epidemic went through monthslong city-wide lockdowns, during which period, social media platforms were primary ways for this population to acquire COVID-19 related information. Psychological health of young adults on campus is concerned throughout this research. This study integrated the theory of psychological capital (PsyCap) in research whether and how social media information overload could impact students’ psychological capital under the context of 2022 COVID-19 outbreak in Shanghai. Findings from this research shed light on the underpinning mechanism of whether and how social media information overload shapes risk perception in the student population within Shanghai, and explore how students’ correspondingly emotional coping associates with their psychological inner being.
Methods
A cross-sectional study among students who encountered with emergency outbreaks in Shanghai from March to June, 2022 was conducted. Over 400 valid samples were used to construct the following analysis. Hierarchical linear regression analysis was conducted using SPSS Statistics Version 26. The chain mediated model was verified using PROCESS.
Results
Information overload is positively related to personal risk perception and societal risk perception. Risk perception leads to emotional coping in university students, which correspondingly predicts the psychological capital of these individuals in face of public health emergencies. Though information overload caused by social media is negatively related to students’ mental well-being, it contributes to emotional coping in a positive sense.
Conclusions
Information overload due to social media usage accounts for risk perception on both a personal-level and a societal-level, which encourages students’ adoption of emotional coping strategies, thus leading to predictions of students’ psychological capital. This study identifies a chain mediated model structured by variables including information overload, risk perception, emotional coping, and psychological capital of university students during the 2022 outbreak in Shanghai.
Preparation and Characterization of FTO/nZnO/CH3NH3PbI3/C/Cu Perovskites Solar Cell
Authors: ElMohamady Noha , Taher Fatema abdel-Rahman , El-sayed Galila M , Elshikh Salah , Mahdy Iman A. 
Published: August 2023

Abstract

Nano ZnO is prepared by the sol-gel method and acts as a conductive seed layer in perovskite solar cells. Methylamine lead iodide CH3NH3PbI3 (MAPbI3) was prepared by two steps method of methylamine iodide CH3NH3I/nZnO/FTIO glass and nPbI2. The effect of ZnO semiconductors nanostructure was studied due to its physical properties arising from quantum confinement. Also, it is considered problematic for Perovskite solar-cells due to the notorious instability of the nZnO/perovskite interface, particularly in the case of using MAPbI3 and its effect on the cell efficiency. The nanostructure is characterized using different techniques. The nZnO was introduced into the Perovskite solar cells structure to improve the electron extraction efficiency of Perovskite solar cells, and to increase the stability of Perovskite solar cells using Commercial Carbon is used as whole transparent material. The current-voltage curves of the FTO/nZnO/CH3NH3PbI3/C/Cu solar cell with a perovskite structure have high conversion efficiencies and stability η = 80.41%.
TRIM2, S100A14, CYP4B1, LMO7, and SFN are signature genes in the progression of idiopathic pulmonary fibrosis epithelial cells to their lung adenocarcinoma comorbidities: a comprehensive analysis based on single-cell RNA sequencing data and RNA transcriptome data
Authors: Zhou Xianqiang , Tan Fang , Zhang Tiansong 
Published: August 2023

Abstract
Background
Patients with idiopathic pulmonary fibrosis (IPF) have a significantly higher prevalence of lung adenocarcinoma (LUAD) than normal subjects, but the underlying association is unclear. This study aims to reveal the potential mechanisms by which IPF progresses to LUAD comorbidity.
Methods
The raw data involved in the study were obtained from the Gene Expression Omnibus (GEO) database. Sc-RNA seq data were applied to identify specific cell types for disease. Differential expression analysis and Weighted Gene Co-Expression Network Analysis (WGCNA) were used to screen for differentially expressed genes (DEGs) and modular signature genes (MSGs) shared by IPF and LUAD. Genes intersecting DEGs and MSGs were considered hub genes. After performing 3 kinds of machine learning algorithms on epithelial cell-derived hub genes, we captured epithelial cell-derived signature genes (EDSGs) shared. External cohort data were exploited to validate the robustness of EDSGs. We adopted immunohistochemical staining to reveal the protein expression levels of EDSGs. K-M plots denoted the survival prognosis of EDSGs in LUAD patients. Based on EDSGs, we constructed a TF-Gene-miRNA regulatory network and predicted the candidate drugs. Molecular docking can validate the strength of action between candidate drugs and EDSGs.
Results
Epithelial cells were a specific cell type shared by IPF and LUAD. And then we obtained 650 DEGs and 1773 MSGs, which were shared by IPF and LUAD. As for 379 hub genes, we performed pathway and functional enrichment analysis, aiming to explore the molecular mechanisms shared. By analyzing sc-RNA seq data, we identified 1234 marker genes of IPF epithelial cell-derived and 1481 of LUAD. And these epithelial cell-derived marker genes shared 8 genes with 379 hub genes. Furthermore, through the machine learning algorithm, we got 5 EDSGs, including TRIM2, S100A14, CYP4B1, LMO7, and SFN. The ROC curves validated that EDSGs have high accuracy in predicting the onset of LUAD comorbidity in IPF patients. The TF-Gene-miRNA network revealed potential regulatory mechanisms of EDSGs. And molecular docking suggested strong binding activity between Thalidomide, Docetaxel, and Imatinib and their corresponding targets.
Conclusion
Our study preliminarily identified potential mechanisms for the progression of IPF to its LUAD comorbidity, which will inform subsequent studies.
Development and Evaluations of the Broadband Ocean Bottom Seismometer (Yardbird-BB OBS) in Taiwan.
Authors: Ching-ren Lin , Liao Yi-Chun , Kuo Ban-Yuan , Wang Chau-chang , Chen Hsin-Hung , Jang Jia-pu , Chen Po-chi , Lin Feng-Sheng , Chang Kun-Hui , Chang Hsu-kuang 
Published: August 2023

Abstract

This study focuses on the development and evaluation of the Broadband Ocean Bottom Seismometer (called Yardbird-BB OBS) in Taiwan. The Yardbird-BB OBS is a critical instrument used to recording seismic signals in deep-sea environments. Rigorous testing and evaluation methods are employed to ensure optimal performance and data recording capabilities. Components such as the data logger, seismic sensor leveling mechanism, acoustic device, and internal wiring undergo thorough performance evaluations prior to assembly. This guarantees the selection of high-performance components and verifies their functionality, preventing issues like data loss or incomplete recording. Once assembled, the Yardbird-BB OBS undergoes a deployment test in the deep sea, typically lasting 3–6 months, to record seismic signals from various sources worldwide. Recorded data from deployments in the Okinawa Trough in 2016 and 2017 are analyzed, highlighting significant seismic events such as a magnitude 7.8 earthquake in New Zealand and a magnitude 6.3 earthquake resulting from a nuclear test by North Korea. The OBS's performance is assessed through waveform analysis, specifically focusing on P-wave arrival times and waveform quality. The results showcase successful automatic leveling adjustment for the seismometer. These high-quality data recordings have valuable research applications, including the study of plate tectonics, estimation of crustal ages, determination of seafloor ambient noise, and improvement of earthquake location accuracy. Additionally, the study presents methods for verifying instrumental self-noise, dynamic range, digitization sensitivity, linearity error, clock drift, and power consumption of the data logger. Calibration procedures and evaluation methods provide valuable insights into the performance characteristics of the Yardbird-BB OBS. The comprehensive evaluations and testing methods outlined in this study contribute to a better understanding and enhancement of the Yardbird-BB OBS, enabling its effective deployment for long-term underwater data recording and valuable scientific research.
Transcription factor TFAP2B exerts neuroprotective effects targeting BNIP3 mediated mitophagy in ischemia/ reperfusion injury
Authors: Peng Yong , Jia Jiaoying , Zhang Mingming , Ma Wenjia , Cui Yan , Yu Mengqiang 
Published: August 2023

Abstract
Cerebral ischemia-reperfusion injury (CIRI) leads to malignant brain edema, blood-brain barrier destruction and neuronal apoptosis. N6-methyladenosine (m6A) RNA modification in CIRI has still limited. MeRIP and RNA-sequencing were performed of middle cerebral artery occlusion and reperfusion (MCAO/R) rats to find novel potential molecular targets. Transcription factor TFAP2B, was standed out of which its m6A abundance decreased associated with a marked reduction of its mRNA based on joint interactive bioinformatics analysis of the MeRIP and RNA-Sequencing data. It was suggeted TFAP2B could have an role in CIRI. Functionally, overexpression of TFAP2B in cultrued primary neurons could effectively improve the cell survival and pro-survival autophagy in parallel with reduced cell apoptosis during OGD/R in vitro. Through the RNA-sequencing of TFAP2B overexpressed primary neurons and subsequent validation experiments, it was found that mitophagy receptor BNIP3 was one of an important target of TFAP2B in OGD/R neurons through which TFAP2B could bind to its promoter region for further transcriptional activation of BNIP3, thereby enhancing BNIP3 mediated mitophagy to protect against OGD/R injury of neurons. Lastly, TFAP2B was demonstrated to alleviated the MCAO/R damage to a certain extent in vivo. Although it was failed to confirm TFAP2B dysregulation was m6A dependent in current research, this is the first study of TFAP2B in CIRI field with important guiding significance.