bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recycling ABS from WEEE with peroxo- modified surface of titanium dioxide particles: alteration on antistatic and degradation properties
Authors: Oliveira Iago. M. , Gimenez Jessica C. F. , Xavier Gabriela T. M. , Ferreira Marco A. B. , Silva Caio M. P. , Camargo Emerson R. , Cruz Sandra A. 
Published: June 2023

Abstract
The increasing concern about plastic disposal and its impact on the environment has led to the necessity to reuse these materials, completing their life cycle within the circular economy mentality: production, use, recycling, and reuse. One of the residues that has caused great concern is the so-called waste electrical and electronic equipment (WEEE). The reintroduction of a recycled material back into the market requires some type of modification since the recycling process lightly alters the general properties of those materials. In this work, we studied the recycling of ABS - one of the polymers most found in waste electrical and electronic equipment - and its modification through commercial titanium dioxide (TiO2) and modified with peroxide groups (TiO2 – OPM). The TiO2 – OPM have interesting electrical properties due to their lower band gap values, which results in them being good candidates for the modification of recycled polymers for WEEE applications. For this, different percentages of particles were incorporated into ABS from the electro-electronic industry. Aspects of degradation, rheology, and antistatic were analyzed. A good interaction between the particle and polymer is observed, especially for those modified with the peroxo group. Nevertheless, it is observed that this modification promotes a reduction in the initiation of exothermic reactions for the butadiene phase, which seems to be a positive aspect because it preserves the acrylonitrile-styrene phase. The interaction is observed rheologically, indicating the formation of a percolated network that favors antistatic characteristics, even with a reduced amount of TiO2-OPM. This work presents a framework for the development of more sustainable materials with concepts of a circular production system.
Prehospital treatment targets for patients with traumatic brain injury requiring tracheal intubation. A retrospective analysis of 308 patients
Authors: Knapp Jürgen , Doppmann Pascal , Huber Markus , Meuli Lorenz , Albrecht Roland , Sollid Stephen , Pietsch Urs 
Published: June 2023

Abstract
Background
Traumatic brain injury (TBI) remains one of the main causes of mortality and long-term disability worldwide. Maintaining physiology of brain tissue to the greatest extent possible through optimal management of blood pressure, airway, ventilation, and oxygenation, improves patient outcome. We studied the quality of prehospital care in TBI patients by analyzing adherence to recommended target ranges for ventilation and blood pressure, prehospital time expenditure, and their effect on mortality, as well as quality of prehospital ventilation assessed by arterial partial pressure of CO2 (paCO2) at hospital admission.
Methods
This is a retrospective cohort study of all TBI patients requiring tracheal intubation on scene who were transported to one of two major level 1 trauma centers in Switzerland between January 2014 and December 2019 by Swiss Air Rescue (Rega). We assessed systolic blood pressure (SBP), end-tidal partial pressure of CO2 (petCO2), and paCO2 at hospital admission as well as prehospital and on-scene time. Quality markers of prehospital care (petCO2, SBP, prehospital times) and prehospital ventilation (paCO2) are presented as descriptive analysis. Effect on mortality was calculated by multivariable regression analysis and a logistic general additive model.
Results
Of 557 patients after exclusions, 308 were analyzed. Adherence to blood pressure recommendations was 89%. According to petCO2 45% were normoventilated, and 29% had a SBP ≥ 90 mmHg and were normoventilated. Due to the poor correlation between paCO2 and petCO2, only 33% were normocapnic at hospital admission. Normocapnia at hospital admission was strongly associated with reduced probability of mortality. Prehospital and on-scene times had no impact on mortality.
Conclusions
paCO2 at hospital admission is strongly associated with mortality risk, but normocapnia is achieved only in a minority of patients. Therefore, the time required for placement of an arterial cannula and prehospital blood gas analysis may be warranted in TBI patients requiring on-scene tracheal intubation.
Reclassification of Adolescent Ambulatory Prehypertension and Unclassified Blood Pressures by 2022 American Heart Association Pediatric Ambulatory Blood Pressure Monitoring Guidelines
Authors: Hill-Horowitz Taylor , Merchant Kumail , Reyes Laura Castellanos , Singer Pamela , Dukkipati Haripriya , Frank Rachel , Sethna Christine B , Basalely Abby 
Published: June 2023

Abstract
Background
The 2022 American Heart Association (AHA) pediatric ambulatory blood pressure monitoring (ABPM) guidelines eliminated the prehypertension phenotype and blood pressure loads in ABPM interpretation criteria. Adolescents who were prehypertensive or unclassified according to the 2014 AHA pediatric ABPM guidelines will be reclassified as having hypertension or normotension. The epidemiology and association of reclassification phenotype with target organ damage (TOD) is not yet known.
Methods
A single center retrospective review of adolescents ages 13–21 years old between 2015–2022 was performed. Adolescents diagnosed with prehypertension or unclassified by the 2014 AHA pediatric ABPM guidelines were reclassified by the 2022 definitions. Logistic regression models adjusted for body mass index z-score evaluated the association of reclassification phenotype with left ventricular hypertrophy (LVH).
Results
Among 88 adolescents with prehypertension, 68% (N = 60) were reclassified as hypertensive. The majority (58%, N = 35) of hypertensive reclassification was based on isolated nocturnal blood pressures ≥ 110/65 mmHg. Taller males were more likely to reclassify as hypertensive. Adolescents reclassified as hypertensive had a greater-than-six-fold increased odds of LVH in adjusted models [OR 6.4 95%CI 1.2–33.0, p = 0.027]. Of 40 adolescents with unclassified blood pressures, 37.5% (N = 15) reclassified to normotension. There were no significant clinical or demographic variables associated with reclassification category nor was there an association with LVH.
Conclusions
The new ABPM guidelines effectively reclassify adolescents who were previously prehypertensive as normotensive or hypertensive based on risk of TOD. Further studies are needed to describe the long-term outcomes of ABPM phenotypes with the implementation of these guidelines.
Using Experience-based Co-design to develop mobile/tablet applications to support a person-centred and empowering stroke rehabilitation
Authors: Marwaa Mille Nabsen , Guidetti Susanne , Ytterberg Charlotte , Kristensen Hanne Kaae 
Published: June 2023

Abstract
Aim To investigate and describe the process of using Experience-based Co-design (EBCD) to adapt and develop mobile/tablet applications to support a person-centred and empowering stroke rehabilitation.
Setting Two cross-sectoral stroke rehabilitation settings in Denmark comprising six rehabilitation units.
Participants Stroke survivors (n=23), significant others (n=18), occupational therapists (n=12), physiotherapists (n=9), representative of a patient organization (n=1), application developers (n=3) and researchers (n=2).
Method A structured, facilitated EBCD approach comprising six stages was used to co-produce a service that aimed to address the priorities and needs of all relevant end-users. Data were collected by interviews, participant observations, notes on “flip sheets” and written feedback on the content in the apps and on the instruction pages. Data were analyzed descriptively and with a constructivist grounded theory analysis.
Results The application platforms “Mit Sygehus” and “Genoptræn.dk” were adapted and new functions were developed to support the needs identified by all end-users. Relevant evidence-based knowledge, person-centred exercises and guidelines using video recordings were the most important among the developed solutions in the applications to support person-centred and empowering stroke rehabilitation. Furthermore, easy, and seamless communication were considered important.
Conclusions EBCD facilitated the adaptation and development of applications to support a person-centred and empowering stroke rehabilitation. Participants experienced that their contribution was considered important and valued.
In vitro and in vivo assessment of the safety and applications of potential probiotics isolated from Egyptian fermented food products
Authors: Tawab Fatma I. Abdel , kadr Menna H. Abd El , Sultan Amany M. , Hamed Ehdaa O. , El-Zayat Ayatollah S. , Ahmed Marwa N. 
Published: June 2023

Abstract
Lactic acid bacteria are of major concern due to their health benefits. Fermented food products comprise variable lactic acid bacterial isolates demonstrating probiotic properties. In this study, we isolated and functionally characterized lactic acid bacterial strains isolated from different Egyptian fermented food sources as probiotics. Only four isolates showed probiotic attributes and are considered to be safe for their implementation as feed or dietary supplements. Additionally, they were shown to exert antimicrobial activities against pathogenic bacteria and anticancer effects against the colon cancer cell line Caco-2. The Enterococcus massiliensis IS06 strain was exclusively reported in this study as a probiotic strain with high antimicrobial, antioxidant, and anti-colon cancer activity. Hitherto, few studies have focused on elucidating the impact of probiotic supplementation in vivo. Therefore, in the current study, the safety of the four isolates was tested in vivo through the supplementation of rats with potential probiotic strains for 21 days. The results revealed that probiotic bacterial supplementation in rats did not adversely affect the general health of rats. The Lactiplantibacillus plantarum IS07 strain significantly increased the growth performance of rats. Furthermore, the four strains exhibited increased levels of antioxidants such as superoxide dismutase and glutathione in vivo. Consistently, all strains also showed high antioxidant activity of the superoxide dismutase enzyme in vitro. Overall, these findings demonstrated that these isolated potential probiotics harbor desirable characteristics and can be applied widely as feed additives for animals or as dietary supplements for humans to exert their health benefits and combat serious diseases.
Sub-Region Model for Flux-Switching Permanent Magnet Machine with Outer Rotor and Inner Rotor Distinctly to Calculate Cogging Torque, Electromagnetic Torque and Inductance (self and mutual)
Authors: Shirzad Ehsan 
Published: June 2023

Abstract
This paper presents a general analytical subdomain model for the computation of magnetic field distribution in any number of stator slots and rotor poles in presence of only permanent magnet (PM) and excitation (2-layer) for flux switching permanent magnet machines (FSPMMs) with outer and inner rotor. The target of this work is to elaborate an analytical general method based on subdomain model for prediction of magnetic field, cogging torque, electromagnetic torque and inductance (mutual and self) by solving Maxwell law. To evaluate subdomain model, the effect of saturation is neglected due to considering infinite permeability for cores. The presented general subdomain method is comparable to finite element method (FEM) where the mesh elements can be compared to the number of harmonic terms used in each subdomain. To validate, the proposed model results are compared with those obtained from FEM.
Identification of COVID-19 Cuproptosis-Related Gene Subtypes and Construction of Prediction Models Using Multiple Machine Learning Methods
Authors: Hu Renwang , Liu Can , Li Dan 
Published: June 2023

Abstract
Objective
To identify the subtypes of cuproptosis-related genes associated with COVID-19 and construct prediction models with multiple machine learning methods.
Methods
Whole-genome sequencing data of normal people and COVID-19 patients (GSE163151 dataset, GSE156063 dataset) were downloaded from GEO database, and the differentially expressed cuproptosis-related genes were screened. Consistent clustering typing was used to divide the COVID-19 patients into two types (C1, C2). The correlation between the infiltration of 22 kinds of immune cells and the expression of cuproptosis-related genes in different typing COVID-19 patients was studied. GSVA method was used to study the gene variation set of different typing COVID-19 patients. WGCNA clustering method was used to construct gene co-expression network between normal people and COVID-19 patients, and between different typing (C1, C2) COVID-19 patients respectively, and the gene modules with the largest correlation coefficient and statistical significance were selected to screen out the key genes. Multiple machine learning methods (GLM, RF, SVM, XGB) were used to construct prediction models for the key gene sets, and the models with the highest accuracy and stability were selected.
Results
Thirteen differentially expressed cuproptosis-related genes (FDX1, LIPT1, DLD, DLAT, PDHA1, PDHB, GLS, ATP7B, SLC31A1, ATP7A, DLST, DBT, GCSH) were screened. Based on these 13 genes, 138 COVID-19 patients were divided into two types (C1, C2). There were obvious differences in the infiltration of immune cells, expression of cuproptosis-related genes and gene pathway variation sets (GSVA) between different typing COVID-19 patients. Finally, 11 genes that were significantly correlated with COVID-19 patients and different typing were selected by WGCNA method. The prediction model constructed by SVM method with 5 key genes (RSAD2, AIM2, ZBP1, DDX60L, GBP1) had strong predictive ability (training group AUC = 0.956, validation group AUC = 0.931).
Conclusion
Multiple cuproptosis-related genes expressions are significantly correlated with COVID-19 subtypes (C1, C2) and the amount of immune cells infiltration; The prediction model constructed by SVM method can predict the probability of patient infection with COVID-19 well.
The impact of regular taxation on non-oil economic growth: Evidence from a PANEL-ARDEL study in the Arab Gulf Cooperation Council countries – during the period 1990-2019
Authors: ASSMA GUERFI 
Published: June 2023

Abstract
This study aimed to identify the contribution of fiscal ordinary to achieving economic growth outside of hydrocarbons in the GCC countries during the period 1990–2019. By using the PMG method and by taking GDP outside of hydrocarbons as a dependent variable, and fiscal regular revenues as the main independent variable, in addition to other independents variables. The study found that the decline in oil prices harmed the sample countries during the study period which made them implement many reforms to their tax structures to ensure the sustainability of public revenues outside the fiscal petroleum.
Jel Classification: E62, O47, C22.
Autoimmune Encephalitis and Other Neurological Syndromes With Rare Neuronal Surface Antibody in Children after hematopoietic stem cell transplantation
Authors: Zhang Ming-min , Wang Jing , Sun Dan , Wang Jing-xuan , Zhang Jun-hong , Xu Jia-wei 
Published: June 2023

Abstract
Introduction:
Neuronal surface antibody syndromes (NSAS) are an expanding group of autoimmune neurological diseases, whose most frequent clinical manifestation is autoimmune encephalitis (AE). Anti-N-methyl-D-aspartate receptor (NMDAR) autoimmunity represent the most described form, while other NSAS such as anti-metabotropic glutamate receptor-5 (mGluR5) are rarer and less well-characterized, especially in children.
Case description:
Here, we carried out a case of a 7-year-old girl with abnormal behavior after hematopoietic stem cell transplantation (HSCT). She was diagnosed as anti-mGluR5 AE and the Electroencephalogram (EEG) showed increased number of generalized slow waves in the waking-period. Intravenous injection of gamma globulin and methylprednisolone followed by oral administration of prednisone tablets. During hormone shock therapy, levetiracetam was given anti epileptic treatment. The abnormal behaviors improved significantly after treatment.
Discussion and Evaluation:
The mechanism of anti-mGluR5 AE after HSCT is unclear. Impairment of glutamatergic synaptic transmission by anti-neuronal surface GluR antibodies is increasingly recognized as a major cause of AE in humans.
Conclusions:
To our knowledge, this is the first report on rare pediatric NSAS of anti-mGluR5 AE after HSCT. An improved characterization may aid our recognition and treatment in children. Serum antibody testing in HSCT patients with negative cerebrospinal fluid autoimmune antibodies may allow the early identification and treatment of anti-mGluR5 AE.
The association between urinary lead and risk of kidney stones: A population-based study
Authors: Liu Chang , Liang Dan 
Published: June 2023

Abstract
Background The negative effects of lead exposure on human health have attracted widespread attention. Our present study focused on assessing the relationship between urinary lead levels (ULL) and the risk of kidney stones in US adults.Methods We used data from NHANES 2007–2018 for this cross-sectional study, where participants had complete data on ULL and kidney stones. The correlation between ULL and kidney stones was explored by weighted multiple logistic regression analysis. In addition, we also performed subgroup analysis and interaction tests.Results A total of 8325 subjects were included, and the prevalence of kidney stones was 9.90%. In the fully adjusted model, we observed a positive association between ULL and the risk of kidney stones (OR:1.07, 95% CI: 1.01–1.14, p = 0.03). Participants in the highest quartile of ULL had a 64% higher risk of kidney stones than those in the lowest quartile of ULL (OR:1.64, 95% CI: 1.05–2.57, p = 0.03). Subgroup analysis and interaction test indicated that the association between ULL and the risk of kidney stones was similar in different population settings.Conclusion ULL was associated with an increased likelihood of kidney stones.
Adaptive resistance to cefiderocol in carbapenem-resistant Acinetobacter baumannii (CRAB): microbiological and clinical issues
Authors: Desmoulin Anissa , Sababadichetty Loïk , Kamus Laure , Daniel Marion , Feletti Lucie , Allou Nicolas , Potron Anais , Leroy Anne-Gaëlle , Jaffar-Bandjee Marie-Christine , Belmonte Olivier , Garrigos Thomas , Miltgen Guillaume 
Published: June 2023

Abstract

Purpose: Determining the best available therapy for carbapenem-resistant Acinetobacter baumannii (CRAB) infections is a challenge. Cefiderocol is an attractive alternative drug effective against many resistance mechanisms in Gram-negative bacteria. However, its place in the treatment of Acinetobacter baumannii infections remains unclear and much debated, with contradictory results.
Methods: We describe here the case of a 37-year-old man with ventilator-associated bacteraemic CRAB pneumonia in an intensive care unit. He was initially treated with a combination of colistin and tigecycline, and was then switched onto colistin and cefiderocol. We then used a new accessible protocol to test 30 CRAB isolates (OXA-23/OXA-24/OXA-58/NDM-1) for adaptive resistance to cefiderocol (ARC) after exposure to this drug.
Results: After clinical failure with the initial combination, we noted a significant clinical improvement in the patient on the second combination, leading to clinical cure. No ARC was detected in the two OXA-23 case-CRAB isolates. All NDM CRAB isolates were resistant to cefiderocol in standard tests; the OXA-23, OXA‑24 and OXA‑58 CRAB isolates presented 84.2%, 50% and 0% ARC, respectively.
Conclusions: ARC is not routinely assessed for CRAB isolates despite frequently being reported in susceptible isolates (69.2%). Subpopulations displaying ARC may account for treatment failure, but this hypothesis should be treated with caution in the absence of robust clinical data. The two main findings of this work are that (i) cefiderocol monotherapy should probably not be recommended for OXA-23/24 CRAB infections and (ii) the characterisation of carbapenemases in CRAB strains may be informative for clinical decision-making.
Transforming Telecom Revenue- The impact of OTT Service
Authors: Dahal Madhu Sudan 
Published: June 2023

Abstract
The telecom industry's primary revenue streams used to be voice and SMS, but with the rise of Over the Top (OTT) services, this scenario is changing. This paper aims to analyze the transition from the voice and SMS era of cellular communication to a data-centric business. The study uses ten years data of voice traffic, data traffic and SMS count and their respective revenue of Telecom operators of Nepal. The research explores how user behavior is shifting from voice and SMS to data usage patterns, provides valuable insights into the changing landscape of the telecom industry and impact of OTT services on traditional revenue streams. It also highlights the need for telecom operators to adapt to these changes by embracing new technologies and providing innovative products to meet the evolving needs of their customers. Finally, the paper provides the various strategies to be implemented by telecom operators in response to revenue loss due to OTT services. It demonstrates that embracing OTTs and providing different products that resemble flat-rate pricing will be the most successful strategy for mobile operators to retain revenues. Additionally, the research reveals that the regulator should resist the push for regulating OTTs and instead facilitate the evolution to flat access pricing.
Clinical impact of timing of surgery on outcomes in preterm infants with surgical necrotizing enterocolitis
Authors: Garg Parvesh Mohan , Riddick Robin , Ansari Md Abu Yusuf , Pittman Isabella , Hillegass William 
Published: June 2023

AbstractBackground:The clinical impact of the timing of surgery on outcomes in preterm infants with surgical necrotizing enterocolitis (NEC) is not well defined.Aim:We sought to investigate the impact of the different timing of surgery from the day of NEC diagnosis on clinical outcomes in preterm infants with surgical NEC.Study Design:Retrospective Cohort Study.Subjects:Preterm 75 infants admitted between January 2013 and December 31, 2018, with an NEC (Bell stage III) diagnosis.Outcomes:Comparison of clinical information by the timing of surgery at three different time points (less and more than 48 hours, 96 hours, and 168 hours) in preterm infants with surgical NEC.Results:75 infants were included in the analysis. Those who received surgery after 48 hours (n= 29/75) had lower median gestational age, lower birth weight, had less pneumoperitoneum, were out born less frequently, had higher acute kidney injury, were intubated and ventilated more frequently, and had higher hemorrhagic and reparative lesions on histopathology than those receiving surgery after 48 hours. Infants receiving surgery after 96 hours had similar trends expect had significantly lower hematocrit and more prolonged parenteral nutrition dependence than less than 96 hours group. The infants receiving surgery after one week had significantly lower birth weight and had higher reparative changes and cholestasis than those receiving surgery < 1 week. There was no significant impact of surgery timing on the length of bowel loss, surgical morbidity, Bronchopulmonary dysplasia, white matter injury, and mortality.Conclusion:The infants receiving surgery later were young and smaller and received parenteral nutrition longer with no significant impact on morbidities and mortality. Our data point out that there are advantages of operating early with fewer morbidities which need further confirmation and evaluation in large multicentric prospective studies or clinical trials.