bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perceptions and practices surrounding the perioperative management of frail emergency surgery patients: a WSES-endorsed cross-sectional qualitative survey
Authors: Viswanath Mallaika , Clinch Darja , Ceresoli Marco , Dhesi Jugdeep , D’Oria Mario , De Simone Belinda , Podda Mauro , Di Saverio Salomone , Coccolini Federico , Sartelli Massimo , Catena Fausto , Moore Ernest , Rangar Deepa , Biffl Walter L. , Damaskos Dimitrios 
Published: January 2023

Abstract
Background
Frailty is associated with poor post-operative outcomes in emergency surgical patients. Shared multidisciplinary models have been developed to provide a holistic, reactive model of care to improve outcomes for older people living with frailty. We aimed to describe current perioperative practices, and surgeons’ awareness and perception of perioperative frailty management, and barriers to its implementation.

Methods
A qualitative cross-sectional survey was sent via the World Society of Emergency Surgery e-letter to their members. Responses were analysed using descriptive statistics and reported by themes: risk scoring systems, frailty awareness and assessment and barriers to implementation.

Result
Of 168/1000 respondents, 38% were aware of the terms “Perioperative medicine for older people undergoing surgery” (POPS) and Comprehensive Geriatric Assessment (CGA). 66.6% of respondents assessed perioperative risk, with 45.2% using the American Society of Anaesthesiologists Physical Status Classification System (ASA-PS). 77.8% of respondents mostly agreed or agreed with the statement that they routinely conducted medical comorbidity management, and pain and falls risk assessment during emergency surgical admissions. Although 98.2% of respondents agreed that frailty was important, only 2.4% performed CGA and 1.2% used a specific frailty screening tool. Clinical frailty score was the most commonly used tool by those who did. Screening was usually conducted by surgical trainees. Key barriers included a lack of knowledge about frailty assessment, a lack of clarity on who should be responsible for frailty screening, and a lack of trained staff.

Conclusions
Our study highlights the ubiquitous lack of awareness regarding frailty assessment and the POPS model of care. More training and clear guidelines on frailty scoring, alongside support by multidisciplinary teams, may reduce the burden on surgical trainees, potentially improving rates of appropriate frailty assessment and management of the frailty syndrome in emergency surgical patients.
Surgical and perioperative management of flail chest with titanium plates: a French cohort series from a thoracic referral center
Authors: Féray Sarah , Blayau Clarisse , Masmoudi Hicham , Haddad Samuel , Quesnel Christophe , Assouad Jalal , Fartoukh Muriel 
Published: January 2023

Abstract
Background
The development of titanium claw plates has made rib osteosynthesis easy to achieve and led to a renewed interest for this surgery. We report the management of patients referred to the intensive care unit (ICU) of a referral center for surgical rib fracture fixation (SRFF) after chest trauma.

Methods
We performed a retrospective observational cohort study describing the patients’ characteristics and analyzing the determinants of postoperative complications.

Results
From November 2013 to December 2016, 42 patients were referred to our center for SRFF: 12 patients (29%) had acute respiratory failure, 6 of whom received invasive mechanical ventilation. The Thoracic Trauma Severity Score (TTSS) was 11.0 [9–12], with 7 [5–9] broken ribs and a flail chest in 92% of cases. A postoperative complication occurred in 18 patients (43%). Five patients developed ARDS (12%). Postoperative pneumonia occurred in 11 patients (26%). Two patients died in the ICU. In multivariable analysis, the Thoracic Trauma Severity Score (TTSS) (OR = 1.89; CI 95% 1.12–3.17; p = 0.016) and the Simplified Acute Physiology Score II without age (OR = 1.17; CI 95% 1.02–1.34; p = 0.024) were independently associated with the occurrence of a postoperative complication.

Conclusion
The TTSS score appears to be accurate for determining thoracic trauma severity. Short and long-term benefit of Surgical Rib Fracture Fixation should be assessed, particularly in non-mechanically ventilated patients.
A rare coexistence: Poland’s syndrome and cardiac angiosarcoma
Authors: Kizilyel Fatih , Gunay Rafet , Rum Mehmet , Yilmaz Mehmet , Ketenci Bulend 
Published: January 2023

AbstractPoland’s syndrome, a rare genetic disorder that accompanies malignancies, musculoskeletal disorders, cardiac and genitourinary syndromes. There is no study that represents the association between cardiac angiosarcoma and Poland’s syndrome. A 24-year-old female patient previously diagnosed with Poland’s syndrome was admitted to our hospital complaining of dyspnea. Diagnostic imaging showed an irregular mass in the right atrial cavity. After successful surgery, she was discharged uneventfully and the 3rd month oncologic follow-up reveals none of residual mass. The coexistence has not been diagnosed and treated in a cardiac surgery department before. With this presentation, we aimed to contribute to the literature with this presentation, for the right and early diagnosis and management of possible new cases in the future can be diagnosed and treated correctly and early.
Double blind control trial of vitamin D fortified milk on the expression of lncRNAs and adiponectin for patients with metabolic syndrome
Authors: Rashidmayvan Mohammad , Sahebi Reza , Avan Amir , Sharifan Payam , Esmaily Habibollah , Afshari Asma , Nattagh-Eshtivani Elyas , Najar Sedghdoust Fatemeh , Aghasizadeh Malihe , Ferns Gordon A. , Ghayour-Mobarhan Majid 
Published: January 2023

Abstract
Background
Metabolic syndrome (Mets) is a common metabolic disorder in which hypoadiponectinemia is one of the consequences for the body caused by inflammation, and vitamin D may help improve inflammatory symptoms. LncRNAs (long non-coding RNA) play several different regulatory roles in the body. The goal of this study was to see how adding vitamin D to milk affected the levels of adiponectin and inflammatory lncRNAs in the serum of people with Mets.

Methods
This clinical trial was conducted on staff and students between the ages of 30 and 50 at Mashhad University of Medical Sciences and met the International Diabetes Federation’s criteria for Mets. Eighty-two Mets were assigned randomly to one of two groups for ten weeks: fortified milk (FM) with 1500 IU vitamin D or non-fortified milk (NFM). Total RNA was extracted from both frozen clinical samples using Trizol reagent. APQ AS and MALAT1 lncRNA gene expression were measured by Real-Time PCR.

Results
Serum adiponectin levels in the FM group increased significantly compared to the NFM group (p = 0.01). Also, the expression of APQ AS and MALAT1 genes decreased after ten weeks, which showed a significant decrease in APQ AS (p = 0.036).

Conclusion
As in FM, vitamin D may have anti-inflammatory effects and increase adiponectin levels in people with Mets via decreasing APQ AS gene expression.
On new Milne-type inequalities for fractional integrals
Authors: Budak Hüseyin , Kösem Pınar , Kara Hasan 
Published: January 2023

AbstractIn this study, fractional versions of Milne-type inequalities are investigated for differentiable convex functions. We present Milne-type inequalities for bounded functions, Lipschitz functions, functions of bounded variation, etc., found in the literature. New results are established in the area of inequalities. This article is the first to study Milne-type inequalities for fractional integrals.
Significance of Fib4 index as an indicator of alcoholic hepatotoxicity in health examinations among Japanese male workers: a cross-sectional and retrospectively longitudinal study
Authors: Shinoda Hideki , Watanabe Yuya , Fukai Kota , Kasuya Kayoko , Furuya Yuko , Nakazawa Shoko , Honda Toru , Hayashi Takeshi , Nakagawa Toru , Tatemichi Masayuki , Korenaga Masaaki 
Published: January 2023

Abstract
Background
Fib4 index (Fib4) is clinically used as a noninvasive marker of liver fibrosis. In this study, we aimed to preliminarily investigate whether Fib4 can be used to detect individuals who need assessment for alcoholic liver disease (ALD) in the general population by clarifying the detailed association of Fib4 with alcohol consumption and gamma-glutamyl transferase (GGT) among male workers.

Methods
We analyzed data sets on the comprehensive medical examinations of male workers as cross-sectional and retrospectively longitudinal studies. We enrolled 10 782 males (mean age: 52.2 ± 10.2 years) in FY2019 and 7845 males (mean follow-up: 12.6 ± 6.7 years) who could be consecutively followed up for 20 years from FY2000 to FY2019. Data were evaluated using logistic regression and COX proportional analysis.

Results
In the cross-sectional setting, the rate of Fib4 ≥ 2.67 in heavy drinkers (≥ 40 g of ethanol/day) was increased dose dependently in those over 65 years old, and that of body mass index ≥ 30 kg/m2 was increased in those over 60 years old, but not in those with fatty liver. The odds ratio (OR) (95% confidence interval [CI]) for heavy drinking was 4.30 (95% CI = 1.90–9.72), and GGT ≥ 200 IU/L was considerably high (OR = 29.05 [95% CI = 17.03–49.56]). In the longitudinal setting, heavy drinkers and those with GGT ≥ 200 IU/L at 10 years after the baseline showed an increased risk for Fib4 ≥ 2.67 (hazard ratio = 2.17 [95% CI = 1.58–2.98] and 7.65 [95% CI 5.26–11.12], respectively).

Conclusions
The development of Fib4 ≥ 2.67 after 10 years was associated with heavy alcohol drinking and GGT level ≥ 200 IU/L. Therefore, Fib4 combined with GGT could indicate high risk of ALD. However, clinical examinations and course observations are essentially needed.
Evaluation of bacteriological profile of meat contact surfaces, handling practices of raw meat and its associated factors in butcher shops of Arba Minch town, southern Ethiopia-A facility based cross sectional study
Authors: Kanko Tesfaye , Seid Mohammed , Alemu Mathewos 
Published: January 2023

Abstract
Background
Meat is subjected to contamination from a range of sources throughout animal slaughter and its sale. The demand for meat products in Ethiopia has been increased dramatically; especially the consumption of fresh chilled meat becomes a status of symbol.

Objectives
This study aimed to evaluate the bacteriological profile of meat contact surfaces, raw meat handling practices, and its associated factors in butcher shops located in Arba Minch town, southern Ethiopia.

Methods and Materials
A facility-based cross-sectional study was carried out among meat handlers in butcher shops in Arba Minch town from November to December 2020. A pre-tested and semi-structured interviewer-administered questionnaire was used to collect the data on workers meat handling practices and the sterile swab was used to collect samples from selected meat contact surfaces for bacteriological analysis. Statistical Package for Social Sciences (SPSS) version 21 was used for data analysis. Binary logistic regression analysis was utilized to assess the presence and degree of association between raw meat handling practice and independent variables. Adjusted odds ratio with a 95% confidence interval at P-value < 0.05 was considered statistically significant.

Result and Conclusion
This study revealed the knowledge and handling practice gap among meat handlers of butcher shops. Knowledge of food handling hygiene has shown significant association with handling practice [AOR = 4.5 (1.182,17.202)]. The median total viable count of bacterial loads from the swab samples of butchers’ hands, knives, and the tables was 5.60 ± 0.80, 5.60 ± 1.00, 5.70 ± 1.00 log10 Colony-forming unit (CFU)/cm2, respectively. Escherichia coli was the predominant isolate 34(68%) followed by Staphylococcus species 28(56%) and Salmonella species 19(38%). The median total bacterial load obtained from the samples exceeds the acceptable value of less than 5.0 log10 CFU/cm2 on fresh meat. This indicates the need for improvement in the meat handling and processing chain to safeguard the public health against the risks of foodborne bacterial infections.
Which return regime induces overconfidence behavior? Artificial intelligence and a nonlinear approach
Authors: Alp Coşkun Esra , Kahyaoglu Hakan , Lau Chi Keung Marco 
Published: January 2023

AbstractOverconfidence behavior, one form of positive illusion, has drawn considerable attention throughout history because it is viewed as the main reason for many crises. Investors’ overconfidence, which can be observed as overtrading following positive returns, may lead to inefficiencies in stock markets. To the best of our knowledge, this is the first study to examine the presence of investor overconfidence by employing an artificial intelligence technique and a nonlinear approach to impulse responses to analyze the impact of different return regimes on the overconfidence attitude. We examine whether investors in an emerging stock market (Borsa Istanbul) exhibit overconfidence behavior using a feed-forward, neural network, nonlinear Granger causality test and nonlinear impulse-response functions based on local projections. These are the first applications in the relevant literature due to the novelty of these models in forecasting high-dimensional, multivariate time series. The results obtained from distinguishing between the different market regimes to analyze the responses of trading volume to return shocks contradict those in the literature, which is the key contribution of the study. The empirical findings imply that overconfidence behavior exhibits asymmetries in different return regimes and is persistent during the 20-day forecasting horizon. Overconfidence is more persistent in the low- than in the high-return regime. In the negative interest-rate period, a high-return regime induces overconfidence behavior, whereas in the positive interest-rate period, a low-return regime induces overconfidence behavior. Based on the empirical findings, investors should be aware that portfolio gains may result in losses depending on aggressive and excessive trading strategies, particularly in low-return regimes.
Mapping the output of the global literature on the links between gut microbiota and COVID-19
Authors: Zyoud Sa’ed H. , Shakhshir Muna , Abushanab Amani S. , Koni Amer , Shahwan Moyad , Jairoun Ammar A. , Al-Jabi Samah W. 
Published: January 2023

Abstract
Background
The term “human microbiota” refers to populations of microorganisms that live harmoniously in co-existence with humans. They contribute significantly to the host's immunological response when confronted with a respiratory viral infection. However, little is known about the relationship between the human microbiome and COVID-19. Therefore, our objective is to perform a bibliometric analysis to explore the overall structure and hotspots of research activity on the links between microbiota and COVID-19 at the global level.

Methods
The research literature on the microbiota and COVID-19 published between 2020 and 2022 was obtained from the Scopus database. Bibliometric analysis and network visualization were performed with VOSviewer.

Results
Of the 701 publications selected, the USA contributed the most (n = 157, 22.40%), followed by China (n = 118, 16.83%) and Italy (n = 82, 11.70%). Hotspots in this field were “COVID-19 is associated with an altered upper respiratory tract microbiome,” “the effect of antibiotics on the gut microbiome,” as well as “patient nutrition and probiotic therapy in COVID-19.”

Conclusions
The links between microbiota and COVID-19 remain an urgent concern at present, and the use of probiotics or/and antibiotics during the pandemic needs to be further improved. This landscape analysis of the links between the microbiota and COVID-19 will provide a basis for future research.
Is the post-COVID-19 syndrome a severe impairment of acetylcholine-orchestrated neuromodulation that responds to nicotine administration?
Authors: Leitzke Marco 
Published: January 2023

AbstractFollowing a SARS-CoV-2 infection, many individuals suffer from post-COVID-19 syndrome. It makes them unable to proceed with common everyday activities due to weakness, memory lapses, pain, dyspnea and other unspecific physical complaints. Several investigators could demonstrate that the SARS-CoV-2 related spike glycoprotein (SGP) attaches not only to ACE-2 receptors but also shows DNA sections highly affine to nicotinic acetylcholine receptors (nAChRs). The nAChR is the principal structure of cholinergic neuromodulation and is responsible for coordinated neuronal network interaction. Non-intrinsic viral nAChR attachment compromises integrative interneuronal communication substantially. This explains the cognitive, neuromuscular and mood impairment, as well as the vegetative symptoms, characterizing post-COVID-19 syndrome. The agonist ligand nicotine shows an up to 30-fold higher affinity to nACHRs than acetylcholine (ACh). We therefore hypothesize that this molecule could displace the virus from nAChR attachment and pave the way for unimpaired cholinergic signal transmission. Treating several individuals suffering from post-COVID-19 syndrome with a nicotine patch application, we witnessed improvements ranging from immediate and substantial to complete remission in a matter of days.
Magnetic resonance imaging with perfusion and diffusion in assessment of intra-spinal lesions
Authors: Foaad Maryam Hamdy , El Rakhawy Mohamed , Mohsen Mohamed 
Published: January 2023

Abstract
Background
MRI is the imaging modality of choice in detecting and evaluating spinal lesions. However, advanced techniques as diffusion and perfusion studies can help more in differentiation between neoplastic and non-neoplastic lesions. Our study aimed to detect the role of diffusion and T2* perfusion weighted imaging in characterization of different spinal lesions by measuring the relative cerebral blood volume (rCBV) and apparent diffusion coefficient value (ADC) of all lesions, comparing perfusion of lesion in relation to normal cord and detection of diffusion pattern of each lesion by observing its signal intensity at diffusion images and ADC map.

Results
Fifty patients were included in this study. Twenty-five patients were with non-neoplastic lesions and twenty-five patients were with neoplastic lesions. The cutoff value of rCBV was 1.2 in differentiation between neoplastic and non-neoplastic lesions with 92% sensitivity and 100% specificity. The cutoff value of ADC was 1 in differentiation between neoplastic and non-neoplastic lesions with 56% sensitivity and 80% specificity.

Conclusions
Diffusion and perfusion weighted images help in differentiation between neoplastic and non-neoplastic spinal lesions.
Critiquing the Global Clothing Chain in Mauritius
Authors: Brevik-Zender Heidi 
Published: January 2023

Abstract
In The Lives of Loréna (Les vies de Loréna, 2020), the Mauritian novelist Christine Duvergé chronicles the unraveling of her titular protagonist’s seemingly ideal existence while weaving together a double critique of the global fashion industry and Trump-era conservatism in the American heartland. This article focuses on the novel’s sociopolitical critiques, which find expression in expensive fashions and the abusive labor practices of the American overseas apparel industry. Described by Duvergé as a “subversive fairytale,” the novel illuminates a transnational network of capitalist greed, which powers the global clothing chain in which Mauritius has served historically as a vital, if exploited, link. Duvergé humanizes the poverty and physical suffering of garment workers in Mauritius, foregrounding imbalances and interdependencies characterizing today’s global apparel industry. As a North-South border-crossing narrative that integrates the protagonist’s memories of her homeland into how she experiences life in the United States, The Lives of Loréna is a timely addition to contemporary Indian Ocean French-language literature, which is, as Françoise Lionnet and Emmanuel Bruno Jean-François have stated, “producing locally grounded writing with global ambitions.”
Η σχέση της πολυδυναμικότητας και της αυτοαποτελεσματικότητας στα χαρισματικά παιδιά ηλικίας 15-18 στην Ελλάδα
Authors: Σαμψωνίδης Δημήτριος 
Published: January 2023

Η έρευνα αποσκοπεί στην ταυτοποίηση των χαρακτηριστικών της πολυδυναμικότητας στην Ελλάδα, στην επίδραση των δημογραφικών στοιχείων στην μεταβλητή και στην εκτίμηση της σχέση της πολυδυναμικότητας και της αυτοαποτελεσματικότητας στα χαρισματικά παιδιά ηλικίας 15-18. Στην έρευνα συμμετείχαν 103 χαρισματικά παιδιά από τους συλλόγους Mensa και τον Σύλλογο γονέων και κηδεμόνων χαρισματικών και ταλαντούχων παιδιών. Από τα αποτελέσματα, προέκυψαν υψηλά επίπεδα γενικευμένης αυτοαποτελεσματικότητας. Ο Κοινωνικός τύπος επαγγελματικών ενδιαφερόντων βρέθηκε ως επικρατέστερος ακολουθούμενος από τον Πρακτικό και τον Καλλιτεχνικό τύπο. Από τους παράγοντες στατιστικά σημαντική σχέση με την πολυδυναμικότητα βρέθηκε να έχει ο τύπος σχολείου και η ηλικία.
Structured Decision Making to Prioritize Regional Bird Monitoring Needs
Authors: Fournier Auriel M. V. , Wilson R. Randy , Gleason Jeffrey S. , Adams Evan M. , Brush Janell M. , Cooper Robert J. , DeMaso Stephen J. , Driscoll Melanie J. L. , Frederick Peter C. , Jodice Patrick G. R. , Ottinger Mary Ann , Reeves David B. , Seymour Michael A. , Sharuga Stephanie M. , Tirpak John M. , Vermillion William G. , Zenzal Theodore J. , Lyons James E. , Woodrey Mark S. 
Published: January 2023

Conservation planning for large ecosystems has multiple benefits but is often challenging to implement because of the multiple jurisdictions, species, and habitats involved. In addition, decision making at large spatial scales can be hampered because many approaches do not explicitly incorporate potentially competing values and concerns of stakeholders. After the Deepwater Horizon oil spill, establishing baselines was challenging because of (1) variation in study designs, (2) inconsistent use of explicit objectives and hypotheses, (3) inconsistent use of standardized monitoring protocols, and (4) variation in spatial and temporal scope associated with avian monitoring projects before the spill. Herein, we show how the Gulf of Mexico Avian Monitoring Network members used structured decision making to identify bird monitoring priorities. We used multiple tools and techniques to clearly define the problem and stakeholder objectives and to identify bird monitoring priorities at the scale of the entire northern Gulf of Mexico region. Although our example is specific to the northern Gulf of Mexico, this approach provides an example of how stakeholder values can be incorporated into the coordination process of broad-scale monitoring programs to address management, restoration, and scientific questions in other ecosystems and for other taxa. History: This paper was refereed. This paper was accepted for the Special Issue of INFORMS Journal on Applied Analytics—Decision Analysis. Funding: Thanks to the National Fish and Wildlife Foundation [Grant 324423], which supported A. Fournier as a postdoctoral research associate at Mississippi State University. M. Woodrey was supported by the U.S. Department of Agriculture, National Institute of Food and Agriculture, Hatch Project funds, the Mississippi Agricultural and Forestry Experiment Station, National Oceanographic and Atmospheric Administration [Grant NA16NOS4200088 to the Mississippi Department of Marine Resources’ Grand Bay National Estuarine Research Reserve], and the Mississippi Department of Marine Resources [Grant 8200025414]. This publication is a contribution of the Mississippi Agricultural and Forestry Experiment Station. T. Zenzal was supported by the National Oceanic and Atmospheric Administration RESTORE Act Science Program [Grant NA17NOS4510092].