bluuebunny/crossref_metadata_2025_split huggingface dataset:
The influence of stress on the neural underpinnings of disinhibited eating: a systematic review and future directions for research
Authors: Giddens Emily , Noy Brittany , Steward Trevor , Verdejo-García Antonio 
Published: June 2023

AbstractDisinhibited eating involves overconsumption and loss of control over food intake, and underpins many health conditions, including obesity and binge-eating related disorders. Stress has been implicated in the development and maintenance of disinhibited eating behaviours, but the mechanisms underlying this relationship are unclear. In this systematic review, we examined how the impact of stress on the neurobiological substrates of food-related reward sensitivity, interoception and cognitive control explains its role in disinhibited eating behaviours. We synthesised the findings of functional magnetic resonance imaging studies including acute and/or chronic stress exposures in participants with disinhibited eating. A systematic search of existing literature conducted in alignment with the PRISMA guidelines identified seven studies investigating neural impacts of stress in people with disinhibited eating. Five studies used food-cue reactivity tasks, one study used a social evaluation task, and one used an instrumental learning task to probe reward, interoception and control circuitry. Acute stress was associated with deactivation of regions in the prefrontal cortex implicated in cognitive control and the hippocampus. However, there were mixed findings regarding differences in reward-related circuitry. In the study using a social task, acute stress associated with deactivation of prefrontal cognitive control regions in response to negative social evaluation. In contrast, chronic stress was associated with both deactivation of reward and prefrontal regions when viewing palatable food-cues. Given the small number of identified publications and notable heterogeneity in study designs, we propose several recommendations to strengthen future research in this emerging field.
Expressions of emotion as perceptual media
Authors: Rowson Rebecca 
Published: June 2023

AbstractExpressions of emotion pose a serious challenge to the view that we perceive other people’s emotions directly. If we must perceive expressions in order to perceive emotions, then it is only ever the expressions that we are directly aware of, not emotions themselves. This paper develops a new response to this challenge by drawing an analogy between expressions of emotion and perceptual media. It is through illumination and sound, the paradigmatic examples of perceptual media, that we can see and hear objects around us. Instead of screening these objects from view, however, they enable our perception while being transparent to us. With reference to perceptual constancy and transparency, I show how expressions show up in our experience of emotions in a surprisingly similar way. Given this, we can understand expressions as the media through which we perceive emotions and overcome the above challenge to an otherwise attractive view.
Efficient and rapid system of plant regeneration via protoplast cultures of Fagopyrum esculentum Moench
Authors: Zaranek Magdalena , Pérez-Pérez Reneé , Milewska-Hendel Anna , Grzebelus Ewa , Betekhtin Alexander 
Published: June 2023

AbstractIn the present study, a high yield of isolated protoplasts from the agronomically important crop Fagopyrum esculentum was obtained by applying a mixture of cellulase, pectolyase, and driselase. We demonstrated that the yield of morphogenic callus-derived protoplasts was 1 × 106 protoplasts per g of fresh tissue. For hypocotyls used as the protoplast source, the number of released cells was twice lower. The protoplasts, embedded in an agarose matrix and cultured in a modified Kao and Michayluk media supplemented with phytosulfokine, re-enter the cell cycle and start to develop, forming microcalli. The plating efficiency was about 20% in the case of hypocotyl- and morphogenic callus-derived protoplasts. For plant regeneration, the medium was supplemented with different combinations of cytokinin. Somatic embryogenesis and organogenesis occur during the cultivation of the protoplast-derived tissues, depending on the applied protoplast source. For the first time, an effective protoplast-to-plant system for F. esculentum has been developed.
On Experiential Loneliness
Authors: Schmidt Philipp 
Published: June 2023

AbstractPresumably, everyone has, at some point in their lives, felt lonely. Loneliness is, in that particular sense, omnipresent. What it feels like to be lonely can, however, vary significantly. Loneliness is far from being a homogeneous phenomenon. Different kinds of loneliness need to be distinguished, considering its causes, contexts, a person’s capacities to cope with it, and many other factors. This paper introduces the notion of a specific kind of loneliness: experiential loneliness. Experiential loneliness, it will be argued, consists in particular ways of experiencing the world, oneself, and others. Although feelings of being lonely in one way or another can emanate from one’s experience of the world being structured in a particular manner, such kinds of loneliness need not—at least, not always and the whole time—lead to emotional feelings that are concerned with one’s loneliness or the lack of meaningful social relationship. Loneliness can give rise to quite different emotional feelings that sometimes even cover up their provenience from underlying experiential loneliness. The notion of experiential loneliness, it is suggested, helps to tie back certain styles of thinking, desires, feelings, and behaviors to contexts of loneliness. Moreover, it will be argued that the notion can also elucidate the development of feelings of being lonely in contexts in which others are not only around but also available. To develop and enrich the notion of experiential loneliness as well as to exemplify its usefulness, a closer look will be taken at the case of borderline personality disorder, a condition in which sufferers are often plagued by loneliness.
Phytophthora, Nothophytophthora and Halophytophthora diversity in rivers, streams and riparian alder ecosystems of Central Europe
Authors: Corcobado Tamara , Cech Thomas L. , Daxer Andreas , Ďatková Henrieta , Janoušek Josef , Patra Sneha , Jahn Daniella , Hüttler Christine , Milenković Ivan , Tomšovský Michal , Jung Marília Horta , Jung Thomas 
Published: June 2023

AbstractWaterways are ideal pathways forPhytophthoradispersal and potential introduction to terrestrial ecosystems. While manyPhytophthoraspecies from phylogenetic clades 6, 9 and 10 are predominant oomycetes in watercourses due to their adaptation to a lifestyle as saprotrophs and opportunistic pathogens of riparian plants, species from clades 2, 7 and 8 are predominantly soil- or airborne using aquatic habitats as temporal niches for spreading and invading terrestrial sites along the watercourses. In contrast to forest ecosystems, knowledge ofPhytophthoradiversity in watercourses in Central Europe is limited. Between 2014 and 2019 extensive surveys of streams and rivers were undertaken across Austria, in South Moravia, Czech Republic and Žilina province, Slovakia to unveil the diversity and distribution ofPhytophthoraand related oomycetes. In addition, in Austria riparian forests of black alder (Alnus glutinosa) and grey alder (A. incana) in lowlands and in the Alps were examined. A variety ofPhytophthoraspecies from clades 2, 6, 7, 8, 9 and 10 were isolated, with clade 6 species showing the widest distribution and abundance. Furthermore, interspecific clade 6 hybrids and other oomycetes such asHalophytophthora fluviatilisand undescribedNothophytophthoraspp. were also obtained. In riparian alders, symptoms ofPhytophthorainfections were associated with species from theP. × alnicomplex andP. plurivora.Phytophthora plurivorawas most common in alder stands whereasP. uniformiswas the oomycete species occurring at the highest altitude in alpine riparian areas.
Klimawandel ganz nah: Hitzewellen
Authors: Nidens N. , Huber V. , Matthies-Wiesler F. , Schneider A. 
Published: June 2023

ZusammenfassungHintergrundZunehmende Temperaturextreme und Hitzewellen stellen eines der wichtigsten klimawandelbedingten Gesundheitsrisiken für Menschen in Deutschland dar. Sie haben Auswirkungen auf die Mortalität und Morbidität, den Schwangerschaftsverlauf sowie die mentale Gesundheit. Zu den besonders gefährdeten Bevölkerungsgruppen zählen ältere Menschen, Vorerkrankte sowie Säuglinge, Schwangere und Personen, die im Freien körperlich schwer arbeiten oder Sport treiben. Obwohl sich die Mehrheit der hitzebedingten Sterbefälle auf kardiovaskuläre und respiratorische Erkrankungen zurückführen lässt, sind auch nierenbedingte Todesursachen möglich.ProblemstellungWährend Hitzewellen steigt das Risiko für nierenbedingte Morbidität und Mortalität an. Insbesondere treten akute Nierenschädigungen, Harnsteine, Elektrolytentgleisungen und Harnwegsinfektionen auf. Auch chronische Nierenerkrankungen werden als eine mögliche Folge des Klimawandels diskutiert. Für Nierenpatient:innen stellt das Zusammenspiel von Hitze, Luftschadstoffen und anderen Umweltfaktoren eine besondere Belastung dar.SchlussfolgerungNephrolog:innen können durch hitzespezifische Beratung und Behandlung maßgeblich zum Schutz von vulnerablen Patient:innen beitragen. Es ist daher wichtig, dass sie sich entsprechend informieren und weiterbilden und so Hitzeschutzmaßnahmen zum Schutz ihrer Patient:innen und Mitarbeiter:innen in Praxen und Kliniken adäquat umsetzen können.
Utility of eco-friendly microwave-assisted nitrogen-doped carbon dots as a luminescent nano-sensor for the ultra-sensitive analysis of tigecycline in dosage form and biological samples
Authors: Salman Baher I. 
Published: June 2023

AbstractIn the presented work, simple, green, sensitive, and selective nitrogen-doped carbon quantum dots (N-CQDs) were developed as nano-sensor for quantification of tigecycline (TIG) in different matrices. The proposed method is based on microwave synthesis of green nitrogen-doped carbon quantum dots with a high quantum yield (41.39%) and size diameter equal to 2.0 nm from the green juice of Eruca sativa leaves. The relative fluorescence intensity (RFI) of the green synthesized quantum dots (N-CQDs) was quenched at emission 512 nm (excitation 445 nm) after the addition of TIG drug. A good linear range between TIG concentration and quenched fluorescence intensity of N-CQDs in the range 20–300 ng mL−1, with the lower limit of quantitation (LOQ) equal to 8.51 ng mL−1. The proposed method was validated using the international conference of harmonization (ICH) recommendation and bio-analytical validation using U.S. food and drug administration (US-FDA) guidelines. The N-CQDs have been fully characterized using a transmission electron microscope (TEM), dynamic light scattering (DLS), X-Ray photoelectron spectroscopy (XPS), and Fourier-transform infrared spectrometer (FTIR). The suggested technique is a straightforward analytical procedure that can be used in clinical laboratories. Under the optimum condition, TIG was estimated in human plasma with a high percentage of recovery ranging from 96.95 to 98.54%. In addition, the proposed method was applied effectively in milk samples with percentage of recovery equal to 98.90 ± 1.55.
Does national culture impact management control systems? A systematic literature review
Authors: Mitter Christine , Kuttner Michael , Duller Christine , Sommerauer Petra 
Published: June 2023

AbstractThis paper reviews findings on how different dimensions of national culture influence management control systems (MCS). It is based on a comprehensive sample of 43 peer-reviewed journal articles that were identified in a systematic literature search. For the categorization of the results, we refer to Malmi and Brown’s (Manag Account Res;19:287–300, 2008. https://doi.org/10.1016/j.mar.2008.09.003) frequently quoted framework. Our systematic literature review offers a detailed analysis of the sample’s bibliographical characteristics, including the chronological order of publications, journal metrics, article type, and country focus. Our results reveal that the research field is dominated by Hofstede's cultural dimensions theory and that the majority of the sample articles explicitly mention or confirm the influence of national culture on MCS. We demonstrate that the cultural influences on a wide range of different MCS practices, tools and methods are examined, and show that a holistic and comprehensive analysis of the interplay of national culture and the elements of the MCS is mostly missing. Moreover, diverging research designs and contextual factors, different understandings of national culture and especially the often too superficial classification of national culture complicates and inhibits the comparability of the different results. Findings show that the underlying motivations and effectiveness of MCSs differ across national cultures, suggesting that MCSs require adaptation to different national cultures.
Encapsulation of Hydrophobic Apigenin into Small Unilamellar Liposomes Coated with Chitosan Through Ethanol Injection and Spray Drying
Authors: Ang San-San , Thoo Yin Yin , Siow Lee Fong 
Published: June 2023

AbstractDespite the multiple health benefits, natural flavonoid apigenin has poor aqueous solubility that restricts its delivery in foods. This study investigated the potential of spray-dried chitosan-coated liposomes prepared from scalable methods for the food industry as the delivery carriers for apigenin. Apigenin-loaded small unilamellar liposomes produced from ethanol injection had an encapsulation efficiency of 74.88 ± 5.31%. They were electrostatically stabilised via chitosan coating (0.25% w/v) and spray-dried. Spray-dried chitosan-coated apigenin liposomes (SCAL) exhibited the following powder characteristics: yield 66.62 ± 3.08%, moisture content 4.33 ± 0.56%, water activity 0.2242 ± 0.0548, particle size 10.97 ± 1.55 μm, nearly spherical morphology with wrinkles and dents under microscopic observation. Compared with the unencapsulated apigenin, SCAL demonstrated improved aqueous solubility (10.22 ± 0.18 mg/L), higher antioxidant capacity, and stability against simulated gastrointestinal digestion. The chitosan coating gave a slower in-vitro release of apigenin in SCAL (77.0 ± 6.2%) than that of uncoated apigenin liposomes (94.0 ± 5.3%) at 12 h. The apigenin release kinetics from SCAL could be represented by the Korsmeyer-Peppas model (R2 = 0.971). These findings suggest that SCAL could be a promising delivery system of apigenin for functional food applications.
Telepresence in live-stream shopping: An experimental study comparing Instagram and the metaverse
Authors: Barta Sergio , Gurrea Raquel , Flavián Carlos 
Published: June 2023

AbstractAdvances in digital platforms allow influencers to use live shows to showcase products, which has given rise to live-stream shopping. Moreover, new communication forms have emerged, such as the metaverse. The social interactions that occur in these immersive environments foster influencer-follower interactions. This research compares the impact of live-stream shopping on followers’ experiences and behaviors on two communication channels (live shows on Instagram and in the metaverse) and analyses the moderating role of content involvement in telepresence. Data were collected in a between-subjects quasi-field experiment. Two scenarios that differed in degree of telepresence were created, a live show on Instagram and a live show in the metaverse. The results showed that telepresence is an important part of the user experience and in the success of live shows. Telepresence was seen to have a major influence on experiential value, but not on instrumental value. Both values provided followers with satisfaction with the experience. This satisfaction generated stickiness intention and intention to recommend the influencers’ live shows. The effect of telepresence on experiential value was greater for followers less involved with the influencer’s content. This research is pioneering in comparing an established platform, Instagram, with the metaverse. Despite the greater experiential value provided by the metaverse, to increase its instrumental value metaverse spaces needs to be further developed.
Experiencing Data on Location: A Case Study of Visualizing Air Quality for Citizens
Authors: Huber Christoph , Nagel Till , Stuckenschmidt Heiner 
Published: June 2023

AbstractVisualizing urban data has different purposes. Besides more traditional goals such as supporting experts to decide on smart city policies, supporting citizens to understand aspects of the city relevant to one’s everyday life needs different visualization approaches. In contrast to urban dashboards, which typically show various data sources in a more or less unified way, visualizations tailored for one specific task may be more appropriate for citizens. This paper introduces data experience points where people can experience data on location on their own device, and explore and understand urban phenomena through visualizations. Based on an expert workshop, we propose a set of design goals for these data experience points, and demonstrate the concept through a case study of visualizing air quality data. We designed and implemented multiple prototypes in this case study, and gathered feedback at a public outreach event.
Freedom and Anxiety: A Psychoanalytic Exploration of the Super-ego in the Postmodern Era
Authors: Jesus Sofia 
Published: June 2023

AbstractThe purpose of this study is to explore how the postmodern era may have altered the functioning of the Freudian super-ego. The aim of this paper is to create a discussion about which super-ego features may have disappeared, which may have been modified and which may have remained unaltered. Some of the hypotheses are illustrated through the discussion of the COVID-19 pandemic. The analysis suggests that postmodernity has modified aspects of the super-ego, promoting emancipation and the reduction of repression, while it generated uncertainty, new anxieties and an unconditional obligation to conform to unrealistic ideals of happiness and freedom.
Changes in tropospheric air quality related to the protection of stratospheric ozone in a changing climate
Authors: Madronich S. , Sulzberger B. , Longstreth J. D. , Schikowski T. , Andersen M. P. Sulbæk , Solomon K. R. , Wilson S. R. 
Published: June 2023

AbstractUltraviolet (UV) radiation drives the net production of tropospheric ozone (O3) and a large fraction of particulate matter (PM) including sulfate, nitrate, and secondary organic aerosols. Ground-level O3 and PM are detrimental to human health, leading to several million premature deaths per year globally, and have adverse effects on plants and the yields of crops. The Montreal Protocol has prevented large increases in UV radiation that would have had major impacts on air quality. Future scenarios in which stratospheric O3 returns to 1980 values or even exceeds them (the so-called super-recovery) will tend to ameliorate urban ground-level O3 slightly but worsen it in rural areas. Furthermore, recovery of stratospheric O3 is expected to increase the amount of O3 transported into the troposphere by meteorological processes that are sensitive to climate change. UV radiation also generates hydroxyl radicals (OH) that control the amounts of many environmentally important chemicals in the atmosphere including some greenhouse gases, e.g., methane (CH4), and some short-lived ozone-depleting substances (ODSs). Recent modeling studies have shown that the increases in UV radiation associated with the depletion of stratospheric ozone over 1980–2020 have contributed a small increase (~ 3%) to the globally averaged concentrations of OH. Replacements for ODSs include chemicals that react with OH radicals, hence preventing the transport of these chemicals to the stratosphere. Some of these chemicals, e.g., hydrofluorocarbons that are currently being phased out, and hydrofluoroolefins now used increasingly, decompose into products whose fate in the environment warrants further investigation. One such product, trifluoroacetic acid (TFA), has no obvious pathway of degradation and might accumulate in some water bodies, but is unlikely to cause adverse effects out to 2100.
Graphical abstract
Patient Waiting Time at Primary Healthcare Centers in Riyadh Region, Saudi Arabia: A Cross-sectional Study
Authors: Almusawi Mona Ahmed , Radwan Nashwa Mohammed , Mahmoud Nagla Eltigani , Haji Alhan Mohammedamin , Alabdulkareem Khaled Ibrahim 
Published: June 2023

Abstract
Background
Patient waiting time can adversely affect health services utilization and continuity of care, impacting patient satisfaction. In Saudi Arabia, there is limited information about the average waiting time at primary healthcare centers. Therefore, this study quantifies patient waiting time for services offered in Ministry of Health primary healthcare centers in Saudi Arabia.

Materials and methods
A cross-sectional study utilizing secondary data from the Health Information System at primary healthcare centers in Riyadh was conducted in December 2020. Ten primary healthcare centers were selected. All patients visiting the selected centers during the study period were included, except those who needed emergency care or came for services without seeing the physician. Data regarding patient waiting time in minutes for different stages of primary healthcare services were collected.

Results
The median total waiting time was 23 min. The median waiting time for pre-consultation and consultation were 6.00 and 6.78 min, respectively. The waiting time for pharmacies in rural primary healthcare centers was 22.1 min, while there was no recorded information regarding pharmacy waiting time in urban primary healthcare centers. The total waiting time at urban primary healthcare centers was longer than at rural primary healthcare centers, with a significant difference between both groups (t =  − 15.5, P < 0.001). Patient age, marital status, educational level, occupation, and weekdays were significant factors influencing waiting time (P < 0.05).

Conclusion
This study reveals positive outcomes regarding the average waiting time in primary healthcare centers in the Riyadh region. Further primary research is recommended.