bluuebunny/crossref_metadata_2025_split huggingface dataset:
Short-term Effects of Cadmium Exposure on Blood Pressure and Vascular Function in Wistar Rats
Authors: Rossi Karoline Alves , Almenara Camila Cruz Pereira , Simões Rakel Passos , Sepulchro Lorraine Christiny Costa , Krause Maiara , Carneiro Maria Tereza W. D. , Padilha Alessandra Simão 
Published: August 2023

Abstract
Chronic cadmium exposure is known to be associated with vascular changes and increased blood pressure, but its short-term effects on the cardiovascular system remain poorly understood. This study aimed to investigate the pressoric and vascular effects of a 7-day exposure to CdCl2 in Wistar rats. The rats were divided in control group (Ct), which received tap water, and the Cd group, which received a 100 mg/L CdCl2 solution via drinking water for 7 days. We analyzed body weight, plasma Cadmium concentration, systolic blood pressure (SBP), and vascular responses. Despite relatively low plasma Cadmium concentration, the Cd group exhibited elevated SBP and increased contractile response to phenylephrine. Endothelium removal and NOS inhibition increased contractions in both groups. In the Cd group's aorta, we observed enhanced levels of phospho-eNOS (Ser1177) and basal NO release. Cd group showed reduced Catalase expression and increased basal release of H2O2, with catalase reducing the contractile response. In arteries pre-contracted with phenylephrine, Cd group showed impaired endothelium-dependent (Acetylcholine) and independent (sodium nitroprussiate - SNP) relaxation responses. However, responses to SNP were similar after pre-contraction with KCl in both groups. These data suggest early effects of Cadmium on blood pressure and aortic function, indicating impaired H2O2-scavenging by catalase. Increased H2O2 due to Cadmium exposure might explain heightened responses to phenylephrine and weakened relaxation responses mediated by the NO-K+-channels pathway. Our findings shed light on Cadmium's short-term impact on the cardiovascular system, providing insights into potential mechanisms underlying its effects on blood pressure regulation and vascular function.
Experimental Mechanical Characterization of Silica Fume-based No-fines Concrete Reinforced by Steel or Nylon Fibers
Authors: Hussain Saddam , Ahmed Zaheer , Ahmed Aqeel , Bedon Chiara 
Published: August 2023

Aims:
In this study, the mechanical characterization of no-fines concrete solutions is addressed experimentally, with the purpose of possibly increasing their strength by using silica fume and embedded fibers (steel and nylon fibers) as possible efficient reinforcement.

Background:
Due to competition between developed and advanced countries, the contemporary construction sector is currently experiencing a shortage of fundamental building materials. In this regard, no-fines concrete is becoming increasingly popular, and it has been proven in the literature that it can offer some advantages as an economic and lightweight solution compared to conventional concrete. However, experiments and investigations are still needed to investigate the potential mechanical advantages for its efficient use in buildings, given that the major limitation compared to normal concrete is represented by limited strength.

Objective:
The primary objective of the present study is to assess the mechanical strength of no-fines concrete samples in which steel fibers, nylon fibers, and partial cement replacement with silica fume are used. For this purpose, no-fines concrete specimens are produced with fixed mix proportions of 1:6 cement-aggregate (c-a) ratio, various coarse aggregate gradations ((20-10) mm and (10-5) mm), and fixed w/c ratio (0.42).

Methods:
The experiments are carried out on cubes, cylinders and prisms of concrete samples with various aggregate solutions. The nominal length of both types of fibers is fixed at 20 mm. Steel fibers with 1 mm in diameter and nylon fibers with 0.3 mm, 0.4 mm, 0.5 mm, or 0.6 mm diameters, respectively, are taken into account to explore their effects on compressive strength, split tensile strength, and flexural strength.

Results:
The presented experimental results showed various mechanical advantages, such as increased compressive, splitting tensile and flexural strength parameters, for most of the examined samples. Nylon fibers, in particular, proved to significantly increase compressive, splitting tensile, and flexural strength values, compared to normal concrete, with additional benefits compared to steel fibers (for the examined arrangements and configurations).

Conclusion:
Overall, the examined compositions and mixtures of silica fume-based no-fines concrete samples encourage further investigations for the optimization of these solutions. In this regard, in addition to mechanical capacities, further key parameters (such as weight, cost, impact on concrete microstructure, etc.) will be taken into account.
Resilience, Burnout and Wellbeing of Nurses during the Third Wave of COVID-19 in Cyprus
Authors: Prodromou Maria , Stylianou Neophytos , Protopapas Andreas , Leontiou Ioannis 
Published: August 2023

Background:
Burnout is a state of physical and emotional exhaustion, and when experienced among healthcare workers, it is a sign of major concern for the health system. COVID-19 has induced a plethora of negative consequences, like extra workload on nurses, emotional stress, risk of infection to close family, and factors leading to burnout.

Aim:
This study aimed to measure the prevalence of burnout and resilience among nurses in Cyprus.

Materials and Methods:
An online questionnaire-based survey using Copenhagen Burnout Inventory and the Conor Davidson scale was carried out among all registered nurses in Cyprus. Burnout and resilience were defined at a cut-off score of 50 for each domain.

Results:
The prevalence of overall burnout was 54.26%. No significant difference was identified between the different demographics collected and burnout prevalence. Burnout was lower in the category of patient-related burnout (32.77%) compared to personal or work-related burnout (68.30% and 66.81%, respectively).

Conclusion:
There has been a significant prevalence of burnout found during the COVID-19 pandemic among nurses. On the contrary, our findings reflect that nurses have high resilience, something that is a benefit to the system as they never stop working. Nurses experiencing burnout have a higher tendency to leave their department/organization and their job, a fact that their management should have in mind. We suggest that management should be proactive and supportive in improving working conditions and providing assurance to employees. The long-term effects of the current pandemic need to be assessed later.
Analisis Pengaruh Penyumbatan Aliran Fluida pada Pipa dengan Metode Fast Fourier Transform
Authors: Wicaksono Fikri , Subekti Subekti 
Published: August 2023

Instalasi perpipaan memiliki peranan yang penting diberbagai industri modern. Perencanaan yang baik sangat penting dalam mendesain sebuah instalasi perpipaan. Salah satu jenis pipa yang paling sering digunakan adalah pipa carbon steel yang memiliki ketahanan dan kekuatan yang baik. Namun disamping kekuatan pipa carbon steel yang baik, tingkat kekerasan pipa jenis ini juga tinggi sehingga cenderung tidak lentur yang mana akan menimbulkan getaran yang cukup kuat dalam pengaplikasiannya. Getaran yang timbul karena adanya fluida (dalam hal ini air) akan menimbulkan masalah serius apabila tidak ditangani dengan benar. Kerusakan struktur pipa dan bangunan dapat terjadi akibat getaran pipa yang ditimbulkan. Untuk itu perlu sebuah perencanaan yang baik dalam membuat desain instalasi perpipaan. Salah satu cara untuk mengurangi getaran yang terjadi pada pipa besi adalah dengan memasang support atau penyangga pada posisi yang benar dan jumlah yang tepat, selain itu debit fluida yang mengalir juga harus diperhitungkan untuk mengurangi getaran yang terjadi pada instalasi perpipaan. Pada eksperimen ini akan dilakukan pengujian menggunakan metode Fast Fourier Transform (FFT) terhadap sebuah instalasi pipa besi dengan variasi bukaan katup untuk mengatur debit air yang mengalir dan jumlah support yang menjadi penyangga pipa untuk mengatasi getaran yang terjadi.Piping installations have an essential role in various modern industries. Good planning is crucial in designing a piping installation. One of the most commonly used pipe types is carbon steel pipe which has good resistance and strength. In addition to the excellent strength, the hardness level is also high, where it tends to be stiff and causing vibrations in its application. The vibrations arising from the presence of fluids (in this case, water) will cause severe problems if not handled properly. Pipe vibration can damage pipe structures and buildings. That is why a good plan in piping installation design is needed. One way to reduce vibrations in metal pipes is to install supports in the correct position and the right amount. The fluid flow must also be taken into account to minimize vibrations in piping installations. In this experiment, testing will be carried out using the Fast Fourier Transform (FFT) method on an iron pipe installation with various valve openings to regulate the water flow and the number of pipe support to minimize vibrations.
Pengaruh Penambahan Unsur Aluminium Murni pada Bahan Aluminium Scrap Terhadap Ketangguhan Impak dan Struktur Mikro Hasil Pengecoran Velg Motor Honda
Authors: Dahlan Ahmad , Rusiyanto Rusiyanto 
Published: August 2023

Tujuan penelitian ini adalah untuk megetahui pengaruh penambahan aluminium murni pada bahan aluminium scrap terhadap ketangguhan impak dan struktur mikro. Paduan yang digunakan nantinya adalah scrap dengan penambahan unsur aluminium murni yang divariasikan. Presentase komposisi didapatkan dari perbandingan unsur aluminium pada velg sepeda motor original market sebesar 92% dan scrap sebesar 81%. Varian material yang diteliti adalah variasi penambahan aluminium sebesar 4%, 8% dan 12%, serta material velg sepeda motor. Sering dikeluhkan karena mengalami beban kejut dan retak karena benturan. Proses pembuatan menggunakan peleburan dengan penambahan aluminium murni. Selanjutnya hasil peleburan diuji secara mekanis menggunakan pengujian kekuatan impak dan stuktur nikro dengan standart ASTM. Hasil dari pengujian diperoleh bahwa penambahan unsur aluminium 12% pada scrap memiliki kekuatan impak terbesar yaitu 0.0347 J/mm2dibandingkan dengan velg sepeda motor sebesar 0,0336 J/mm2. Aluminium yang ditambahkan berfungsi untuk memberikan sifat keuletan pada suatu material sehingga mempengaruhi perubahan sifat mekanis. Terlihat pada hasil struktur mikro memiliki fasa eutetik yang semakin rapat dan hampir memiliki kesamaan dengan velg sepeda motor. Dapat disimpulkan bahwa penambahan aluminium mampu mempengaruhi kekuatan impak yang menyebabkan kerapatan fasa aluminium silikon pada material.This study aimed to determine the effect of pure aluminum addition to aluminum scrap material on impact toughness and microstructure. This experiment studied an alloy of scrap aluminum and the addition of pure aluminum into it in various amounts. A spectrotest yields the aluminum element composition is 92% on the original motorcycle rim and 81% on the scrap aluminum. The studied variation of pure aluminum addition is 4%, 8%, and 12%. The manufacturing process uses smelting, and pure aluminum was added during the process. The smelting products were tested mechanically using impact strength and microstructure according to ASTM standard. The results show that the highest impact strength is from the addition of 12% pure aluminum. The impact strength is 0.0347 J/mm2, compared to the original motorcycle rim of 0.0336 J/mm2. The added aluminum serves to provide ductility to the alloy, increasing its mechanical properties. Test results show that the microstructure has an increasingly tight eutectic phase and has almost the same characteristics as the original motorcycle rim. It can be concluded that the addition of aluminum affects the impact strength, in which it causes a dense aluminum-silicon phase of the material.
Pengembangan Bahan Ajar pada Mata Kuliah Perawatan dan Perbaikan Mesin di Pendidikan Vokasional
Authors: Ardian Aan , Ristadi Febrianto Amri , Elisananda Victor 
Published: August 2023

Penelitian ini bertujuan untuk: (1) Menghasilkan produk media bahan ajar yang sesuai dengan kebutuhan Jurusan Pendidikan Teknik Mesin Universitas Negeri Yogyakarta, (2) Mengetahui kelayakan bahan ajar mata kuliah Perawatan dan Perbaikan Mesin Jurusan Pendidikan Teknik Mesin Universitas Negeri Yogyakarta. Peneliti menggunakan penelitian pengembangan Research and Development (RD). Subjek penelitian dan pengembangan bahan ajar ini yaitu 4 dosen ahli materi, 4 dosen ahli media, dan 46 mahasiswa Jurusan Pendidikan Teknik Mesin Universitas Negeri Yogyakarta. Penelitian ini menghasilkan produk bahan ajar mata kuliah Perawatan dan Perbaikan Mesin Jurusan Pendidikan Teknik Mesin. Bahan Ajar mata kuliah Perawatan dan Perbaikan Mesin ini dinyatakan layak berdasarkan penilaian produk yang rerata keseluruhan mendapat nilai 3,35 dengan klasifikasi “Sangat Baik”. This paper reports a study that examined the design and evaluation process of a learning object material (LOM) in Machinery Maintenance and Repair. The study's main objective is: (1) to develop a LOM that is most suitable for the Mechanical Engineering Education study program and (2) to evaluate the LOM per the Study Program's requirements. The study implements the Research and Development method. Research Subjects are material experts comprising 4 lecturers, four learning media experts, and 46 students. The research output is a LOM for Machinery Maintenance and Repair qualified for teaching and learning in the Mechanical Engineering Study Program. The study's results suggested that the LOM is suitable and classified as "Very Good," averaging a total point of 3,35.
PERUBAHAN BUDAYA KERJA INDUSTRI DENGAN MODEL-BASED DEFINITION
Authors: Ristadi Febrianto Amri , Ngadiyono Yatin , Surono Surono 
Published: August 2023

Pendekatan Definisi Berbasis Model atau Model-based Definition (MBD) semakin populer di berbagai industri yang sebelumnya telah berhasil memanfaatkan Computer-aided Design (CAD) secara optimal. Dengan integrasi anotasi, keterangan gambar dan informasi keteknikan lain pada model 3 dimensi (3D) secara langsung, proses desain, manufaktur dan inspeksi akan lebih cepat dan efisien. Namun, pendekatan ini belum banyak diterapkan di industri nasional dan artikel penelitian skala nasional tentang MBD pun tidak ditemukan. Metode yang digunakan dalam penelitian ini adalah artikel review dengan penelusuran artikel pada database ilmiah menggunakan kata kunci, rentang waktu publikasi, serta kesesuaian dan kelayakan artikel. Hasil dari artikel review ini menunjukkan berbagai manfaat dari inisiatif MBD yang mampu mentransformasikan budaya kerja di industri dan sangat potensial untuk diterapkan di industri skala nasional. Artikel ini juga membahas mengenai kekurangan yang masih ada pada implementasi MBD. Dengan pendekatan MBD diharapkan dapat meningkatkan kualitas desain, kualitas produk, efektivitas biaya, serta mengurangi waktu dari tahap desain hingga tahap pemasaran produk. Selain itu MBD diharapkan dapat bersinergi dengan metode lain yang digunakan dalam daur hidup produk.
TANGGAPAN CIVITAS AKADEMIK SEKOLAH TERHADAP PENGENDALIAN RESIKO DI BENGKEL TEKNIK MESIN SMK PIRI SLEMAN
Authors: Multazam Ahmad Muhyi , Djatmiko Riswan Dwi 
Published: August 2023

Penelitian ini memiliki tujuan untuk mengetahui upaya pengendalian risiko Kesehatan dan Keselamatan Kerja (K3) di bengkel teknik mesin SMK PIRI Sleman ditinjau dari tanggapan civitas akademik sekolah. Penelitian ini merupakan penelitian deskriptif dengan pendekatan kuantitatif. Populasi dalam penelitian ini adalah civitas akademik sekolah yang berjumlah 16 responden. Metode pengumpulan data menggunakan angket, dengan jumlah 50 butir pernyataan mengenai pengendalian resiko. Hasil penelitian menunjukan bahwa usaha pengendalian resiko eliminasi dan substitusi yang diberikan kepada kepala jurusan memiliki nilai 69,44 dan 58,33; pada usaha pengendalian teknik yang diberikan kepada kepala bengkel memiliki nilai 79,16; pada usaha pengendalian administratif yang diberikan kepada guru kelas memiliki rata-rata nilai 71,87; sedangkan nilai rata-rata siswa kelas XI pada usaha penggunaan APD adalah 72,62. Hasil rata-rata keseluruhan nilai yaitu 70,28. Dengan demikian, usaha pengendalian resiko yang dilakukan di bengkel teknik mesin SMK PIRI Sleman belum tercapai secara keseluruhan dalam menghilangkan potensi bahaya yang dapat terjadi.
Analisa Gaya Potong Minimal pada Alat Kupas Singkong Sistem Vertikal
Authors: Kurniawan Perwita , Putra Ivanda Bintang Cahya , Saputra Tri Hannanto , Hutama Adhi Setya 
Published: August 2023

Proses pengupasan singkong bukanlah hal yang mudah apabila dilakukan secara otomatis. Bentuk singkong yang tidak seragam merupakan tantangan tersendiri dalam mendesain sebuah mesin pengupas singkong. Ketidakseragaman bentuk ini menyebabkan rendahnya efisiensi pengupasan, baik dari segi waktu maupun volume daging yang ikut terkupas. Berdasarkan hal tersebut, maka perlu dikembangkan sebuah model pengupasan yang efisien dan efektif. Salah satu model yang dikembangkan adalah model alat pengupas singkong sistem vertikal. Pada desain alat pengupas ini, dikembangkan sebuah prototype untuk menguji pengaruh desain pisau terhadap gaya yang mempengaruhi ketebalan kupas ketela. Metode untuk penelitian ini dimulai dari pembuatan desain, dilanjutkan dengan pembuatan purwarupa alat pengupas untuk menguji desain. Penelitian pengambilan gaya potong dilakukan dengan menggunakan pisau potong purwarupa yang memiliki ketebalan 2,00 mm. Pengujian dilakukan secara berulang dengan diferensiasi gaya sebesar 1 N hingga kulit singkong dikupas dengan gaya 20 N. Berdasarkan data hasil pengujian, tampak bahwa untuk mengupas singkong lokal hingga bersih dengan alat kupas kulit singkong sistem vertikal, dibutuhkan gaya potong minimal sebesar 10 N, dengan ketebalan kupas rata-rata 0,43 mm.
Kinerja pengawas sekolah yayasan pada jenjang pendidikan menengah pertama: perspektif guru dan kepala sekolah
Authors: Safitri Heriani Dhia Ayu , Putri Nia Amanda , Prasetyo Gian Bagus , Sumekar Panji Adipura , Maisyaroh Maisyaroh 
Published: August 2023

Fungsi pengawasan dalam manajemen pendidikan menjadi salah satu peran penting, guna mencapai tujuan pendidikan agar berjalan sesuai yang ditetapkan. Sayangnya, pelaksanaan pengawasan sekolah di Indonesia ternyata masih menemui hambatan dan kendala yang menyebabkan program tidak berjalan dengan efektif. Penelitian ini bertujuan untuk mencari tahu kinerja pengawas di jenjang sekolah yayasan menengah pertama ditinjau dari perspektif guru dan kepala sekolah. Penelitian dilakukan menggunakan metode deskriptif kuantitatif dengan melibatkan 54 orang diantaranya 51 guru, 2 kepala sekolah, 1 wakil kepala sekolah dari dua sekolah yang berbeda. Hasil penelitian menunjukkan bahwa secara umum, kinerja pengawas di jenjang sekolah menengah pertama mendapat respon yang positif dari guru dan kepala sekolah. Namun masih ada beberapa ruang lingkup tugas pengawas yang perlu perbaikan seperti pemantauan dalam elaborasi kemampuan peserta didik, pemantauan pengelolaan keuangan, dan pembimbingan dalam meningkatkan kompetensi pengelolaan kelas bagi guru.
Parents’ Perceptions of a Serious Game for Educating Families on Prescription Opioid Safety: Qualitative Pilot Study of MedSMARxT: Adventures in PharmaCity
Authors: Abraham Olufunmilola , Nixon Grace Ann , Seitz Laura Louise 
Published: August 2023

Background
Opioid misuse is a pervasive, worsening problem that affects the health of people throughout the United States, including adolescents. There are few adolescent-focused interventions designed to educate them about opioid medication safety. The MedSMARxT: Adventures in PharmaCity, is a serious educational video game that teaches parents and their youths about safe opioid practices.

Objective
This study aimed to elucidate parent’s perceptions of MedSMARxT: Adventures in PharmaCity and its potential use by parents and their adolescents.

Methods
Parents of adolescents aged 12 to 18 years who live in the United States were recruited from April to October 2021 via Qualtrics research panels, social media, email listserves, and snowball sampling. The study participants played MedSMARxT: Adventures in PharmaCity for 30 minutes and then participated in a 30-minute postgame interview via WebEx (Cisco). Questions were developed and piloted to examine adults’ perceptions of the game. Participants were asked three sets of open-ended questions: (1) questions about the game and elements of the game, (2) what they learned from the game, and (3) questions about their experience with games. Audio recordings were transcribed verbatim. Interview transcripts were coded using content and thematic analysis by study team members to identify major themes and subthemes from the data.

Results
Parent participants (N=67) played MedSMARxT: Adventures in PharmaCity and completed a postgame interview. Analysis extrapolated four primary themes from the data: (1) participant gaming experience, (2) perception of game features, (3) educational purpose of the game, and (4) future use of the game. Most participants (n=56, 84%), had at least some experience with video games. More than half of the participants (n=35, 52%) participants, had positive reactions to the game characters and scenes depicted in MedSMARxT: Adventures in PharmaCity and stated they were realistic for adolescents. Most participants (n=39, 58%), would recommend the game to others. Significant difficulties with gameplay navigation were reported by 38 (57%) participants, as well as a slow game pace. All participants were able to accurately identify the overarching goal of the game: opioid or medication safety. The game reinforced existing knowledge for participants, though many (n=15, 22%), reported a new awareness of the need to store opioid medications in a locked area and the availability of medication disposal drop boxes at pharmacies. Participants stated that they would recommend the game for future use by families and youths in various health care and non–health care settings.

Conclusions
The use of a tailored serious game is a novel, engaging tool to educate adolescents on opioid safety. MedSMARxT: Adventures in PharmaCity can be used as a tool for parents and adolescents to facilitate meaningful dialogue about safe and appropriate opioid use.