bluuebunny/crossref_metadata_2025_split huggingface dataset:
Consideration of Flame-Retardant Hook-and-Loop Fasteners Using Phosphate Ester Flame Retardants and the Influence of Their Dispersibility on Flame Retardancy
Authors: Sakai Tomoki , Tabata Isao , Hori Teruo , Hirogaki Kazumasa 
Published: January 2025

Abstract
Generally, organic fibers are flammable due to their molecular structure. However, highly flame-retardant textile products are required for firefighting uniforms and uniforms used in areas where there is a risk of fire, as well as in enclosed spaces such as automobiles, trains, and airplanes. PET fibers made by melt spinning have excellent physical properties and dyeability. And organic phosphorus-based flame retardants generate less toxic gas than halogen-based flame retardants but are inferior in terms of flame retardancy. Most flame retardants are designed to be easily decomposed; thus, they could decompose during melt spinning. Furthermore, crystallization of resins can be inhibited, causing deterioration of physical properties. We utilized ScCO₂ processing technology makes it possible to swell the amorphous parts of resin and impregnate them with functional agents at low temperatures. (e.g., 31.1–120 °C). Utilizing this technology, a hook-and-loop fastener was impregnated with a large amount of a flame retardant to achieve high flame retardancy while maintaining the engagement force. In addition, the decomposition temperatures of flame retardants and their distribution in fibers were analyzed and considered that.
Clinical utility of tumor-infiltrating lymphocyte evaluation by two different methods in breast cancer patients treated with neoadjuvant chemotherapy
Authors: Nagahashi Masayuki , Ishikawa Eri , Nagai Takahiro , Kanaoka Haruka , Oshiro Aoi , Togashi Yusa , Hattori Akira , Tsuchida Junko , Higuchi Tomoko , Nishimukai Arisa , Murase Keiko , Takatsuka Yuichi , Kihara Takako , Ling Yiwei , Okuda Shujiro , Hirota Seiichi , Miyoshi Yasuo 
Published: January 2025

Abstract

Purpose
The aim of this study was to examine the clinical utility of tumor-infiltrating lymphocytes (TILs) evaluated by “average” and “hot-spot” methods in breast cancer patients.

Methods
We examined 367 breast cancer patients without neoadjuvant chemotherapy (NAC) by average and hot-spot methods to determine the consistency of TIL scores between biopsy and surgical specimens. TIL scores before NAC were also compared with the pathological complete response (pCR) rate and clinical outcomes in 144 breast cancer patients that received NAC. TIL scores evaluated by the two methods were predicted from clinicopathological data using random forest regression.

Results
Surgical specimens showed higher TIL scores than biopsy specimens using the hot-spot method (p < 0.001), while biopsy and surgical specimens showed similar TIL scores using the average method. There was a linear relationship between the pCR rate and TIL scores determined using hot-spot (p < 0.001) and average methods (p = 0.001). Patients without pCR and low TILs by the average method had significantly worse overall survival compared to other patients (p = 0.02). The root mean squared errors of the predicted TIL score for the test set were 19.662 (hot-spot) and 10.955 (average).

Conclusion
The average method may have an advantage for breast cancer patients receiving NAC, since the TIL score using this method is more consistent between biopsy and surgical specimens, and it associates better with clinical outcomes. Our exploratory study showed that machine learning from clinicopathological data may better predict TIL scores assessed by the average, rather than hot-spot, method.
Differentially Expressed Nedd4-binding Protein Ndfip1 Protects Neurons Against Methamphetamine-induced Neurotoxicity
Authors: Asanuma Masato , Miyazaki Ikuko , Cadet Jean Lud 
Published: January 2025

Abstract
To identify factors involved in methamphetamine (METH) neurotoxicity, we comprehensively searched for genes which were differentially expressed in mouse striatum after METH administration using differential display (DD) reverse transcription-PCR method and sequent single-strand conformation polymorphism analysis, and found two DD cDNA fragments later identified as mRNA of Nedd4 (neural precursor cell expressed developmentally downregulated 4) WW domain-binding protein 5 (N4WBP5), later named Nedd4 family-interacting protein 1 (Ndfip1). It is an adaptor protein for the binding between Nedd4 of ubiquitin ligase (E3) and target substrate protein for ubiquitination. Northern blot analysis confirmed drastic increases in Ndfip1 mRNA in the striatum after METH injections, and in situ hybridization histochemistry showed that the mRNA expression was increased in the hippocampus and cerebellum at 2 h-2 days, in the cerebral cortex and striatum at 18 h-2 days after single METH administration. The knockdown of Ndfip1 expression with Ndfip1 siRNA significantly aggravated METH-induced neurotoxicity in the cultured monoaminergic neuronal cells. These results suggest that drastic increases in Ndfip1 mRNA is compensatory reaction to protect neurons against METH-induced neurotoxicity.
Individuals with disabilities in grassroots football clubs: volunteering and social capital
Authors: Scharfenkamp Katrin , Wicker Pamela , Davies Larissa E. 
Published: January 2025

Abstract
Volunteering might be a leisure activity that supports the development of social capital of individuals with disabilities in organized sports. This study investigates the link between having a disability (i.e., physical, mental, or both), the likelihood and extent of volunteering, and the level of social capital in grassroots football clubs. We further examine a moderating effect of volunteering hours on the relationship between having a disability and social capital. Drawing on leisure constraints theory, individuals with disabilities are assumed to have a lower probability to volunteer than able-bodied individuals. Also, we hypothesize that individuals with disabilities perceive their social capital as lower than able-bodied individuals. Based on the motivational model, we assume that sport volunteers with disabilities perceive a higher social capital if they volunteer more hours. Data were collected via an online survey in seven European countries and targeted at adult volunteers and members in football clubs (n = 16,989 volunteers). Results of regressions show that having a physical disability is significantly negatively associated with the probability to volunteer in a football club. Further, having either a physical or mental disability is significantly negatively related to an individuals’ social capital level. The moderation analyses indicate that volunteers having both types of disabilities perceive a higher social capital if they volunteer more hours per month.
Alarms management with fuzzy logic using wind turbine SCADA systems
Authors: Garcia Márquez Fausto Pedro , Benmessaoud Tahar , Mohammedi Kamal , Marugán Alberto Pliego 
Published: January 2025

Abstract
Supervisory Control and Data Acquisition (SCADA) systems are employed to collect data from sensors and monitor the condition of wind turbines. Thresholds are commonly used to set the alarms, generating many false alarms, downtimes, costs, etc. A real case study is presented to validate the approach. This paper proposes a novel approach based on Fuzzy Logic to analyse the main variables of the SCADA. Pearson’s correlation between variables is employed to reduce the number of variables that are used as inputs in the Fuzzy Logic system. The variables with perfect and strong correlations have been selected as inputs of the Fuzzy system. The signal is studied by considering the difference between the signal and the moving average value because it shows if the signal is close or not to the value in conditions free of faults. The thresholds are used to cluster the data into three groups by a statistical analysis of the new variables, i.e., the variables obtained by the difference between the signal and the moving average value. The approach helps decrease false alarms by using a Fuzzy system. The approach is capable of processing large datasets online. The results have been validated by employing SVM, where the MAPE is analysed between both methods.
Können mit „kraftvoller Erinnerung“ und „absoluter Unordnung“ Museen überhaupt dekolonisiert werden?
Authors: LeGall Yann 
Published: January 2025

Zusammenfassung
Dekolonisierung kann kein friedlicher Prozess sein. Sie bedeutet Proteste, Zusammenstöße und Gegenreaktionen, Gespräche, Vereinbarungen und Misserfolge; sie erfordert ein scharfes Verständnis von den und eine radikale Positionierung gegen die Mechanismen des imperialen Extraktivismus, des Rassenkapitalismus und der neoliberalen Kooptation sozialer Bewegungen. In diesem globalen Kontext der Kämpfe um die Anerkennung indigener Rechte, gegen intersektionale Gewalt und um emanzipatorische und Empowerment-Prozesse spielen auch die kulturellen Institutionen eine Rolle. Lange Zeit behaupteten sie, neutral und universell zu sein, aber ihre auf Lügen aufgebaute Autorität bröckelt. Aktivist_innen und Künstler_innen haben die Museen als eifersüchtige Hüter eines (manchmal mit Blutgeld finanzierten) geplünderten Erbes, die ihre historischen Verbindungen zu Versklavung, rassistischer Wissenschaft und kolonialer Eroberung lange bereitwillig verschwiegen haben, gegeißelt. Sie haben sie aufgefordert, ihre ideologischen Positionen zu ändern und ihre unmoralisch erworbenen Sammlungen zurückzugeben. Aber sollten sie auch verschwinden? Im Rahmen einer lebhaften Debatte über die Zukunft der Museen stellen sich zwei Bücher der schwierigen Aufgabe, daran zu erinnern, was die Entkolonialisierung von Museen und Denkmälern bis heute bedeutet hat und was sie ankündigt.
Prevalence of metal hypersensitivity in pediatric spine surgery
Authors: Emmert A. Scott , Ruan Tiffany , Sherenian Michael G. , Assa’ad Amal H. , Leitsinger Nichole , Schultz Lindsay , Jain Viral V. , Sturm Peter F. , Jones Alvin C. 
Published: January 2025

Abstract

Purpose
Delayed metal hypersensitivity reactions can cause complications in spine surgery. Currently, there is no information on the prevalence of metal hypersensitivity in pediatric patients undergoing spine surgery. The objective of this study is to determine the prevalence of metal hypersensitivity in pediatric patients undergoing spinal instrumentation.

Methods
Retrospective chart review of patients who underwent spinal instrumentation with or without fusion at a single institution, from January 1, 2014, to December 31, 2020, was performed. Patients were pre-screened for history of allergic diseases, including previous reaction to metals, prior to surgery. Patch metal allergy testing (PMAT) for metal hypersensitivity was also performed.

Results
Of the 796 pediatric patients who underwent spinal instrumentation procedures from 2014 to 2020, 118 (15%) screened positive for metal hypersensitivity. However, the number of patients with documented evidence of metal hypersensitivity diminished to 26 (3%) after PMAT verification. Nickel hypersensitivity was most prevalent, with 20 patients (16.9% of positive screening; 2.5% of all instrumented patients) demonstrating positive skin patch tests. The other most prevalent metal hypersensitivities included cobalt in 9 patients (7.6%; 1.1%), manganese in 3 patients (2.5%; 0.4%), and copper in 1 patient (0.8%; 0.1%). with a number needed to treat (NNT) of 5.

Conclusions
This study suggests that routine pre-operative PMAT is not necessary in all pediatric spine patients yet should be considered if patients report a history of prior metal hypersensitivity reactions.
Associations between the Strengths and Difficulties Questionnaire (SDQ) and Tests of Variables of Attention (TOVA) in rural school-aged children in Benin Africa
Authors: Zoumenou Roméo , Costet Nathalie , Boivin Michael J. , Wendland Jaqueline , Bodeau-Livinec Florence 
Published: January 2025

Abstract
Sub-Sahara Africa (SSA) children are at high-risk neurodevelopmentally due to the prevalence of infectious disease, nutritional deficiencies and compromised caregiving. However, few mental health screening measures are readily available for general use. The Strengths and Difficulties Questionnaire (SDQ) has been used as a mental health screening measure in the SSA, but its psychometric properties are not well understood. Five hundred and sixty-six mothers completed the SDQ for their 6-year-old children in rural Benin north of Cotonou. These were mothers who had been part of a malarial and intestinal parasite treatment program and micronutrient fortification intervention program during pregnancy for these children. Their study children (N = 519) completed the computerized Tests of Variables of Attention (TOVA-visual) as a performance-based screening assessment of attention deficit and hyperactivity disorders. In evaluating the relationship between the SDQ and TOVA, we controlled for maternal risk factors such as depression, poor socioeconomic status and educational level, along with the child’s schooling status. TOVA measures of impulsivity were significantly related to SDQ emotional and hyperactivity/inattention difficulties. TOVA inattention was related to SDQ emotional difficulties. The triangulation of maternal risk factors (e.g., depression), the SDQ and the TOVA can provide effective screening for mental health issues in SSA children.
A Tale of Two Jubas: Metastasian Opera and Racialized Difference
Authors: PERITZ JESSICA GABRIEL 
Published: January 2025

AbstractPietro Metastasio’s opera Catone in Utica (Rome, 1727) represents ancient Roman imperial politics through the recurring trope of ‘enslavement’. Reading Catone alongside Metastasio’s sources, from Lucan to Addison, reveals how the poet’s de-particularizing representational code converted historical modes of racialization into a generalizing Cartesian moral framework, and thereby demonstrates how the continuing influence of post-Enlightenment constructs of biological race has obscured the multiplicity of racialisms in earlier contexts. Turning from a physiological episteme to an earlier, ‘unassimilated space’ limned by poetics, sentimentality, and song, this article takes Metastasian opera seria as a window onto historically contingent conceptions of racialized difference.
The “One Carceral State”: Mass Incarceration and Carceral Citizenship in Palestine/Israel
Authors: Ben-Natan Smadar , Boulus Dana , Le Penne Shirley 
Published: January 2025

AbstractUsing the concept of the carceral state, this article articulates how Israel’s control of the West Bank and the Gaza Strip has shifted to a nondemocratic one-state paradigm. While, initially, Israel operated a separate military carceral system for these areas, between 2000 and 2006 it dismantled the military system, transferred most Palestinian prisoners into Israel, and rebranded its civilian prison service as the National Prison Authority, making it the sole agency responsible for the incarceration of Palestinians. This reorganization consolidated a single carceral system inside Israeli territory—the one carceral state— which serves as crucial evidence of the de facto one-state paradigm and forms a centerpiece of this new regime in Israel/Palestine. By analyzing a broad range of archival and administrative documents and 168 Supreme Court decisions on the management of prisons and Palestinian prisoners, this study reveals how the massive “exclusionary inclusion” of the Palestinian prisoner population in Israeli state law and its administrative mechanisms changes the entire landscape of the Israeli settler-colonial citizenship regime. Palestinian prisoners become “carceral citizens” of the “one state” and are subject to a parallel, alternate legality, in which they expand their repertoire of resistance against the wider racialized and repressive regime across Palestine/Israel.
Ion‐Mediated Tearing and Kink Instabilities in the Earth's Magnetosphere: Hybrid‐Vlasov Simulations
Authors: Zaitsev I. , Cozzani G. , Alho M. , Horaites K. , Zhou H. , Kit A. , Pfau‐Kempf Y. , Hoilijoki S. , Ganse U. , Battarbee M. , Papadakis K. , Suni J. , Dubart M. , Tesema‐Kebede F. , Workayehu A. , Tarvus V. , Kotipalo L. , Koikkalainen V. , Turc L. , Palmroth M. 
Published: January 2025

AbstractWe explore the three‐dimensional structure of ion‐kinetic instabilities in a thin current layer using a hybrid‐Vlasov simulation of the Earth's magnetosphere. The simulation shows the simultaneous growth of tearing and kinking instabilities, which develop in the Sun‐Earth and dawn‐dusk directions, respectively, within the magnetotail current sheet. The formation of flux ropes indicates the development of the tearing instability, while flapping‐type cross‐tail oscillations arise from the kink instability. We consider both instabilities as independent polarizations, albeit sharing a common source: demagnetized ions forming crescent‐shape distributions at the center of the current layer. These oscillations exhibit spatiotemporal characteristics within the proton‐scale range, featuring a growth time on the order of 40–80 proton gyroperiods and a wavelength of approximately 15–30 proton skin depths.
DNA replication stress underpins the vulnerability to oxidative phosphorylation inhibition in colorectal cancer
Authors: Zhao Xiao Hong , Han Man Man , Yan Qian Qian , Yue Yi Meng , Ye Kaihong , Zhang Yuan Yuan , Teng Liu , Xu Liang , Shi Xiao-Jing , La Ting , Feng Yu Chen , Xu Ran , Narayana Vinod K. , De Souza David P. , Quek Lake-Ee , Holst Jeff , Liu Tao , Baker Mark A. , Thorne Rick F. , Zhang Xu Dong , Jin Lei 
Published: January 2025

Abstract
Mitochondrial oxidative phosphorylation (OXPHOS) is a therapeutic vulnerability in glycolysis-deficient cancers. Here we show that inhibiting OXPHOS similarly suppresses the proliferation and tumorigenicity of glycolytically competent colorectal cancer (CRC) cells in vitro and in patient-derived CRC xenografts. While the increased glycolytic activity rapidly replenished the ATP pool, it did not restore the reduced production of aspartate upon OXPHOS inhibition. This shortage in aspartate, in turn, caused nucleotide deficiencies, leading to S phase cell cycle arrest, replication fork stalling, and enrichment of the p53 pathway, manifestations of replication stress. The addition of purine nucleobases adenine and guanine along with the pyrimidine nucleoside uridine restored replication fork progression and cell proliferation, whereas the supplementation of exogenous aspartate recovered the nucleotide pool, demonstrating a causal role of the aspartate shortage in OXPHOS inhibition-induced nucleotide deficiencies and consequently replication stress and reductions in proliferation. Moreover, we demonstrate that glutamic-oxaloacetic transaminase 1 (GOT1) is critical for maintaining the minimum aspartate pool when OXPHOS is inhibited, as knockdown of GOT1 further reduced aspartate levels and rendered CRC cells more sensitive to OXPHOS inhibition both in vitro and in vivo. These results propose GOT1 targeting as a potential avenue to sensitize cancer cells to OXPHOS inhibitors, thus lowering the necessary doses to efficiently inhibit cancer growth while alleviating their adverse effects.
The green hydrogen ambition and implementation gap
Authors: Odenweller Adrian , Ueckerdt Falko 
Published: January 2025

Abstract
Green hydrogen is critical for decarbonizing hard-to-electrify sectors, but it faces high costs and investment risks. Here we define and quantify the green hydrogen ambition and implementation gap, showing that meeting hydrogen expectations will remain challenging despite surging announcements of projects and subsidies. Tracking 190 projects over 3 years, we identify a wide 2023 implementation gap with only 7% of global capacity announcements finished on schedule. In contrast, the 2030 ambition gap towards 1.5 °C scenarios has been gradually closing as the announced project pipeline has nearly tripled to 422 GW within 3 years. However, we estimate that, without carbon pricing, realizing all these projects would require global subsidies of US$1.3 trillion (US$0.8–2.6 trillion range), far exceeding announced subsidies. Given past and future implementation gaps, policymakers must prepare for prolonged green hydrogen scarcity. Policy support needs to secure hydrogen investments, but should focus on applications where hydrogen is indispensable.
Phylogeographic analyses reveal recent dispersal and multiple Wolbachia infections of the bright-eyed ringlet Erebia oeme within the European mountain systems
Authors: Mewis Valentine , Wendt Martin , Schmitt Thomas 
Published: January 2025

Abstract
The genus Erebia comprises numerous species in Europe. Due to preference of cold environments, most species have disjunct distributions in the European mountain systems. However, their biogeographical patterns may differ significantly. The Bright-eyed ringlet Erebia oeme is widespread in high-altitude grasslands of the European high mountains, hence showing a disjunct distribution pattern. Over its distribution, E. oeme shows high morphological variability indicating pronounced intraspecific differentiation. We analysed two mitochondrial (COI, Cytb) and eight nuclear markers as well as the Wolbachia surface protein-coding gene (WSP). A total of four lineages were identified: two Balkan lineages, one Slovenian lineage as well as one lineage containing all other individuals (Alps, Massif Central, Pyrenees). COI data only indicate a fifth lineage in the southern Carpathians. The region of origin of E. oeme is most likely the western Balkans. From here, E. oeme spread to the eastern Balkan area and further to the southern Carpathians as well as to Slovenia, from where it rapidly crossed the Alps to Massif Central and Pyrenees. Wolbachia was found to be highly prevalent with multiple strains, partly within one population. However, recent Wolbachia impact on the mitochondrial DNA and consequently influence on the intraspecific genetic structure was not detected.