bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of feeding mustard oil cake and soybean meal alone or in combination in calf starter on growth and blood metabolites of dairy calves
Authors: Sarker Md. Abid Hasan , Hossain Nobin , Arefin Sumaiya , Bari Md. Sadakatul , Habib Md. Rezwanul , Khandakar Md. Mehedi Hasan , Islam Md. Zakirul , Islam Mohammad Ashiqul , Rashid Md. Harun-ur- , Siddiki Mohammad Shohel Rana 
Published: July 2023

Abstract

The study was designed to envisage the changes in growth measurements and blood metabolites of crossbred dairy calves in response to calf starters feeding with different protein sources. All calves were fed colostrum until they were three days old. Then, calves were given 2.5 L of fresh whole milk for up to 10 days and 3 L of fresh whole milk for up to 56 days. Calves were fed a farm starter (control), other dietary groups starter containing mustard oil cake (MOC), soybean meal (SM), and a mixture of MOC and SM as MOCSM protein sources. Starting on day 21, all of the calves received starter feeds. On day 56, they were weaned, and the study included calves until day 70. Data were recorded on dry matter intake, growth measurements and blood nutrients profile. Calves consumed greater DM when MOC in the starter was supplied, which was 22.5% more than that of the control-fed group. Calves feeding with SM and MOCSM consumed almost similar quantities of DM at 220.87 and 224.87 g/head/day, respectively. The BWG of calves increased significantly by 5.04 and 4.06% more in the MOC-fed group than in the SM and MOCSM groups. MOC, SM, and MOCSM-fed calves had similar (p>0.05) BLG; however, the control diet had significantly lower BLG. Blood glucose levels did not vary among the calves fed the control, MOC, SM, and MOCSM diets. Significantly higher serum albumin, urea, and BUN concentrations were found in MOC diet-fed calves than in others. Calcium and phosphorus concentration varied significantly among dietary groups and was noticeably lower in the control group compared to the other dietary groups. The results revealed that calf starters endowed with MOC as a protein source and in combination with SM were found advantageous in improving body growth and development.
APVC2021 Automated failure diagnostic system for a cylinder of the hydraulic pressing machine
Authors: LI Zhe , Terashima Osamu , Takeda Naoyuki , Shige Koki 
Published: July 2023

Abstract
Due to the impact of the COVID-19 pandemic and declining working-age populations in certain countries, manufacturing and production sites have actively enhanced production efficiency and labor productivity by incorporating digital technologies. In light of these trends, we have developed a system aimed at swiftly assessing the operational status of machinery in order to optimize production efficiency within a manufacturing company, thereby reducing the time required for machine inspection and repair. To efficiently identify failures and anomalies in hydraulic presses, we have implemented a machine learning-based failure diagnostic system. Vibrational acceleration sensors were installed on the cylinder, the primary component of the press machine, and continuous signal data was collected. By establishing a model based on standard deviation, crest factor, and maximum signal values for normal operation, deviations and temporal changes in the data were utilized to detect failures and anomalies. Consequently, it is feasible to predict the occurrence of failures by monitoring these variations.
Absence of sympathetic innervation hampers the generation of tertiary lymphoid structures upon acute lung inflammation
Authors: Riffard Clémence , Letaïef Laïla , Azar Safa , Casrouge Armanda , Brunet Isabelle , Teillaud Jean-Luc , Dieu-Nosjean Marie-Caroline 
Published: July 2023

Abstract
Background Tertiary lymphoid structures (TLS) are lymphoid organs present in inflammatory non-lymphoid tissues. Studies have linked TLS to favorable outcomes for patients suffering from cancers and infectious diseases, but the mechanisms underlying their formation are poorly elucidated. In particular, the innervation of secondary lymphoid organs raises the question of the involvement of sympathetic nerve fibers in TLS organogenesis.
Methods We established a model of lipopolysaccharide-induced pulmonary inflammation based on 5 daily intranasal instillations in which lymphoid aggregates form and evolve toward mature TLS. Sympathetic nerve fibers were systemically depleted using 6-OHDA injections. TLS were analyzed and quantified using immunohistochemistry and immunofluorescence on lung tissue sections. Lung immune populations were assessed by flow cytometry, and the systemic primary immune response of denervated mice was analyzed by ELISA on plasma samples.
Results Intranasal instillation of LPS in immunocompetent mice induced the transient formation of mature TLS in inflamed lungs. TLS disappeared when acute inflammation resolved. 6-OHDA treatment of LPS-treated animals provoked sympathetic fiber depletion that was associated with a decrease in pulmonary TLS density and with a reduction in lung alveolar space, although the depletion did not fully inhibit TLS formation. We showed a drop in the proportions of naive B cells in the lungs of denervated LPS-treated mice that also exhibited a decrease in their systemic primary antibody response.
Conclusions These data support the existence of neuroimmune crosstalk involved in TLS neogenesis and function and in the control of the naive B-cell pool. Sympathetic nerve fibers could participate not only in TLS formation but also in the in situ mounting of strong primary antibody responses.
Pattern of Cognitive Impairment Among Community Dwelling Elderly in Egypt and Its Relation to Socioeconomic Status
Authors: Tawfik Amany Abass , Adly Nermien Naim , Hamza Sarah Ahmed , Kader Radwa Magdy Abdel 
Published: July 2023

Abstract
Background
Cognitive decline is one of the aging health problems that strongly affects daily functioning and quality of life of older adults and threatening their independence with different levels of cognitive health among people from different socioeconomic groups.
Objective
To assess the prevalence and pattern of cognitive impairment among community dwelling elderly in Egypt and the contribution of socioeconomic status to inequality in cognitive impairment.
Material and Methods
This study involved 470 elderly participants ≥ 60 years, males and females. The Montreal Cognitive Assessment (MoCA) was used to assess the prevalence of cognitive impairment, Hachinski ischemic score (HIS) to investigate type of cognitive impairment, Ain Shams Cognitive Assessment (ASCA) to assess pattern of specific cognitive domain affection, and an Egyptian Socioeconomic status (SES) scale was used to describe the SES of participants.
Results
The prevalence of cognitive impairment was 50.2% that was distributed as 37.7% for MCI and 12.5% for Dementia. The most common type of cognitive impairment was degenerative type (47.8%). Pattern of specific domain affection among cognitively impaired subjects, ranged from 94% for visuospatial function to 12.7% for abstraction. Cognitive impairment was significantly associated with increasing age, female sex, marital status single or widow, low education and with increasing total number of comorbidities and positive family history of cognitive impairment. Cognitive impairment was mainly concentrated in the economically disadvantaged population (low educational level, non-occupied, limited computer use, low income and bad sanitation).
Conclusion
In Egypt, cognitive impairment is significantly prevalent and concentrated among those who are in low socioeconomic status. Increasing educational level of low SES population and improving their access to healthcare services will help to improve the inequity of cognitive impairment.
Major cardiovascular risk factors such as diabetes, high blood pressure and obesity in the municipality of Niakhene in 2020 in Senegal
Authors: Diallo Amadou Ibra , Bassoum Oumar , Sow Polele , Drame Serigne Mbacke , Ba Mouhamadou Faly , Diongue Fatoumata Binetou , Ndiaye Ibrahima , Ba Ndèye Amy , Tine Jean Augustin Diègane , Faye Adama , Seck Ibrahima 
Published: July 2023

Abstract
INTRODUCTION
Non-communicable diseases such as diabetes and high blood pressure are a heavy health and economic burden in low-income countries. This work aimed to study the prevalence of diabetes, arterial hypertension, and obesity as well as their associated factors in the Niakhene commune in rural Senegal.
METHOD
This was a cross-sectional, descriptive, and analytical survey among subjects aged at least 18 years and residing in the municipality of Niakhene carried out in October 2020. A systematic random survey, stratified according to sex and sections was carried out. The questionnaire was constructed from the framework of the STEPS 2015 World Health Organization tools and a literature review. This questionnaire was associated with anthropometric, blood sugar and blood pressure measurements. Descriptive and analytical analyzes were performed with R 4.0.2 software.
RESULTS
A total of 300 individuals were surveyed. They had a mean age of 35.3 years (SD:16.9), female (52.3%), married (65.7%), and uneducated (67.7%).
The main family history was high blood pressure (42.0%), diabetes (9.0%), and stroke (5.7%). The prevalence of diabetes was 3.7% including 0.7% newly diagnosed. Factors associated with diabetes were advanced age over 60 (ORaj =10.6 95% CI [1.32-232]) and family history of diabetes (ORaj =10.6 95% CI 8 .77 [1.16-65.7]).
On arterial hypertension, the prevalence was 47.7% of which 16.3% were newly diagnosed. It was associated with age and areas of overweight-obesity. Subjects aged 40 to 59 had a 4.1 ORaj (95% CI [1.9-9.3]) times greater risk of being hypertensive and this risk increases with age and people aged 60 and over had a risk of 5.6 ORaj (95% CI [2.37-13.9]). Overweight and obese people with a BMI greater than 25 Kg/m2 were 2.6 ORaj (95% CI [1.25-5.76]) times more at risk of being hypertensive
Overweight was noted in 10.7% and obesity in 3.7%. They were mainly associated with age with people aged 25-39 being 7.5 (95% CI [2.35-33.9]) more at risk than young people aged 18-25.
CONCLUSION
The increasing development of major cardiovascular risk factors should lead health authorities to give crucial importance to the fight against the burden of non-communicable diseases in the context of epidemiological transition.
Systematic review and cumulative analysis of clinical properties of BRAF V600E mutations in PLNTY histological samples
Authors: Baumgartner Michael E , Lang Shih-Shan , Tucker Alexander M , Madsen Peter J , Storm Phillip B , Kennedy Benjamin C 
Published: July 2023

Abstract
Polymorphous low-grade neuroepithelial tumors of the young (PLNTY) represent a rare pediatric-type tumor that most commonly presents as medically refractory epilepsy. PLNTY has only recently been recognized as a distinct clinical entity, having been first described in 2016 and added to the World Health Organization classification of CNS tumors in 2021. Molecular studies have determined that PLNTY is uniformly driven by aberrant MAPK pathway activation, with most tumors carrying either a BRAF V600E mutation or activating FGFR2 or FGFR3 fusion protein. Although it is known that these driver mutations are mutually exclusive, little is known about differences in clinical presentation or treatment outcomes between PLNTY cases driven by these distinct mutations. In this study, we performed a systematic review and cumulative analysis of PLNTY cases to assess whether or not PLNTY tumors carrying the BRAF V600E mutation exhibit different clinical behaviors. By searching the literature for all cases of PLNTY wherein BRAF V600E status was characterized, we compiled a dataset of 62 unique patient instances. Using a logistic regression-based approach, we assessed a primary outcome of what factors of a clinical presentation were associated with BRAF V600E mutations and a secondary outcome of what factors predicted total seizure freedom post-surgical resection. PLNTY cases carrying BRAF V600E mutations in the literature were strongly positively associated with adult patients (p=0.0055, OR=6.556; 95% Conf. Int. = 1.737 – 24.742). BRAF V600E status was also positively associated with tumor involvement of the temporal lobe (p=0.0046, OR=11.036; 95% Conf. Int. = 2.100 – 58.006). Male sex was also positively associated with BRAF V600E status, but the result did not quite achieve statistical significance (p=0.0731). BRAF V600E status was not found to be associated with post-operative seizure freedom. These findings indicate that BRAF V600E-positive PLNTY exhibit characteristic clinical presentations but are not necessarily different in treatment responsiveness.
Neonatal outcomes and follow-up of children born to women with pregnancy- associated cancer: a prospective observational study
Authors: Capozza Michele Antonio , Romano Alberto , Mastrangelo Stefano , Attinà Giorgio , Maurizi Palma , Rivetti Serena , Costa Simonetta , Vento Giovanni , Scambia Giovanni , Ruggiero Antonio 
Published: July 2023

Abstract
Background
During the last decade, there has been a growing number of cases of children born from pregnancy-associated cancer (PAC), however there are currently insufficient data on the follow up to be observed in this category of newborns. Objective of the study was to evaluate the neonatal outcomes of infants born to mother with PAC and the potential adverse effect of chemotherapy during pregnancy.
Methods
Maternal clinical data and neonatal outcomes of child born to mothers diagnosed with PAC were collected; infants were divided into those were and were not exposed to chemotherapy during fetal life and their outcomes were compared.
Results
A total of 37 newborn infants from 36 women with PAC were analyzed. Preterm delivery occurred in 83.8% of the cases. No significant differences in neonatal outcomes were found between infants who were and were not exposed to chemotherapy during pregnancy. The median follow-up period was 12 months.
Conclusions
PAC treatment during the second or third trimester does not seem to be dangerous for the fetus, however infants born from PAC must be carefully evaluated for to rule out the consequences of chemotherapy. Long-term follow-up, especially in children exposed to chemotherapy, should be encouraged to obtain relevant data on long-term toxicity.
Assessing Photovoltaic Power Uncertainty in Low-income Smart Home Energy Management using Geographic Information Systems Data
Authors: Elazab Rasha , Saif Omar , Metwally Amr , Daowd Mohamed 
Published: July 2023

Abstract

Solar-powered homes can be an optimal solution for the lack of continuous power sources problem in initial low-income communities. However, the challenge of PV uncertainty can make it difficult to coordinate this vital solar energy in real-time. This paper proposes a new, low-cost solution for assessing the uncertainty of photovoltaic power generation in smart home energy management systems. The proposed index, inspired by the well-known clearness index, is an adaptive deterministic indicator that only requires free Geographic Information System GIS models and PV power measurement, without the need for expensive high-tech controllers or expert engineers/programmers. The proposed index successfully predicts the daily PV energy with errors of less than 3% for more than 93% of studied days, according to the 2020 measured solar radiation of the studied case.
Lay Healthcare Worker Financial Toxicity Intervention: A Pilot Financial Toxicity Screening and Referral Program
Authors: Parikh Divya Ahuja , Rodriguez Gladys M. , Ragavan Meera , Kerr Elizabeth , Ascuncion Khay , Hansen Jennifer , Srini Sandy , Fan Alice , Shah Sumit , Patel Manali I. 
Published: July 2023

Abstract
Purpose
Financial toxicity is a source of significant distress for patients with urologic cancers, yet few studies have addressed financial burden in this patient population.
Methods
We developed a financial toxicity screening program using a lay health worker (LHW) and social worker (SW) to assess and mitigate financial toxicity in a single academic medical clinic. As part of a quality improvement project, the LHW screened all newly diagnosed patients with advanced stages of prostate, kidney, or urothelial cancer for financial burden using 3 COST tool questions and referred patients who had significant financial burden to a SW who provided personalized recommendations. The primary outcome was feasibility defined as 80% of patients with financial burden completing the SW consult. Secondary outcomes were patient satisfaction, change in COST Tool responses, and qualitative assessment of financial resources utilized.
Results
The LHW screened a total of 185 patients for financial toxicity; 82% (n = 152) were male, 65% (n = 120) White, and 75% (n = 139) reported annual household income > $100,000 US Dollars; 60% (n = 114) had prostate cancer. A total of 18 (9.7%) participants screened positive for significant financial burden and were referred to the SW for consultation. All participants (100%) completed and reported satisfaction with the SW consultation and had 0.83 mean lower scores on the COST Tool post-intervention assessment compared to pre-intervention (95% confidence interval [0.26, 1.41]).
Conclusion
This multidisciplinary financial toxicity intervention using a LHW and SW was feasible, acceptable, and associated with reduced financial burden among patients with advanced stages of urologic cancers. Future work should evaluate the effect of this intervention among cancer patients in diverse settings.
Does The Level of Intercultural Sensitivity of Nurses Affect Their Attitudes Towards The Elderly?
Authors: JAFAROV Gülşah ÜNSAL , RASHİDİ Mahruk , KARAMAN Funda , ÇAKMAK Sultan , Elkin Nurten 
Published: July 2023

Abstract
Aim: The study aimed to examine the relationship between the intercultural sensitivity levels of nurses and their attitudes towards the elderly.
Method: The study was a descriptive research, examining relationships among variables design and was conducted with 202 nurses working in a private, public and university hospital in Istanbul, between the dates of 15 March and 15 June 2023, who volunteered to participate in the research (n=202). In collection of the data “Personal Information Form”, “Intercultural Sensitivity Scale” and “Kogan's Attitudes Toward Old People Scale” were used. Descriptive statistics, independent groups t-test and one-way ANOVA, Kruskal Wallis and Mann Whitney U, spearman correlation tests were used in the analysis of the data.
Results: The mean score of the intercultural sensitivity level of the nurses was 78.21±8.49, the mean score of the attitude level towards the elderly was 127.85±14.93, and a significant negative correlation was found between them. It was determined that there was a statistically significant difference between the nurses' professional experience, the place where they lived for a long time, their recognition and knowledge of the culture of the patient they care for, and their scale scores (p<0.05).
Conclusion: In the study, it was found that the nurses' attitudes towards the elderly were at a good level, their intercultural sensitivity levels were above the average score of the scale, and there was a significant negative correlation with each other. It is recommended to determine the strategies to increase and develop the intercultural sensitivity of nurses and their attitudes towards the elderly in a positive way.
Preparation and Properties of Cellulose Nanofiber/Ti3C2Tx/Polylactic Acid Composite Film
Authors: Yan Xiaofei , Gao Zhaoyang , Wang Chen , Zhu Chenyan , Qi Dongming , Tu Lexi 
Published: July 2023

Abstract
Polylactic acid (PLA), a new renewable and environmentally friendly polymer material, has gained significant attention in recent years. However, its application is limited by challenges such as poor thermal stability, brittleness and limited impact resistance. At present, PLA is predominantly modified through blending, filling and copolymerization methods. The above modification methods can effectively improve the properties of PLA to meet the needs of different applications. In this work, CNF/Ti3C2Tx/PLA composites were prepared by impregnating cellulose nanofibers (CNF) and the novel two-dimensional material Ti3C2Tx into PLA. The effects of CNF and Ti3C2Tx incorporation on the thermal, mechanical and electromagnetic shielding properties of PLA were investigated using various characterization techniques including FT-IR, XRD, DSC, TGA, tensile testing and electromagnetic test characterization. The results showed that CNF and Ti3C2Tx can improve the crystallinity of PLA with a maximum crystallinity of 2.52%. Furthermore, these modifications improved its thermal stability and increase the tensile strength by 177.2%. The addition of Ti3C2Tx not only synergistically enhances the mechanical properties of PLA with CNF, but also imparts electromagnetic shielding performance to the polylactic acid composites. The fundings expand the application of PLA composites in the field of electromagnetic shielding.
Development and application of the online initial graft tension measurement system for anterior cruciate ligament reconstruction
Authors: Chen Yu , Chen Jihang , Zhao Chen , Liao Shiyao , Cui Ze , Zhu Danjie 
Published: July 2023

Abstract
The initial graft tension during ACL reconstruction is an essential mechanical parameter. We established a viscoelastic lateral mechanical measurement model. Based on this model, we designed the online measurement system for the initial graft tension during ACL reconstruction. 22 patients with chronic ACL deficiency were treated by single-bundle ACL reconstruction. 12 patients underwent single-bundle ACL reconstruction (group 1), whereas 10 underwent single-bundle ACL reconstruction using the online tension measurement system (group 2). All patients were followed up with the Lysholm score and International Knee Documentation Committee (IKDC) score to evaluate knee joint function. The Lysholm scores and the IKDC scores of the two groups were significantly higher at 1 month and 3 months after the operation with a significant difference, and the Lysholm scores and the IKDC scores of the instrument group (group 2) was significantly higher than those of the control group with significant difference (group 1). In the same ACL single-bundle reconstruction, the application of the online initial graft tension measurement system can provide quantification for the initial graft tension of ACL, improving the current situation in which only experience can be used to estimate the initial graft tension.