bluuebunny/crossref_metadata_2025_split huggingface dataset:
Real-time contrast enhanced ultrasound-guided percutaneous biopsy in diagnosing gallbladder carcinoma metastasising to the ovaries:a case report
Authors: Wang Jing , Liu Yanjun , Sang Liang , Wan Weina 
Published: February 2023

Abstract
Introduction：Multiple-organ primary tumors can invade the ovary through lymphatic and hematogenous routes presenting as ovarian Krukenberg tumors (KT);however they rarely originate from the gallbladder and are often present as primary ovarian tumors;however,their treatments are totally different.
Patient concerns:A 62-year-old Chinese woman presented with abdominal distension for Six months and a weight loss of 5 kg for two months.
Diagnoses: Base on multiple imaging examinations,the patient was preliminarily diagnosed with a malignant tumor of unknown origin with multiple metastases(liver,gallbladder,right-adnexal,omentum).To identify the origin of the malignancy,the patient received real-time contrast enhanced ultrasound-guided (CEUS-guided) percutaneous biopsy.The postsurgical pathologic examination showed perihepatic hypoecho and right-adnexal mass were both metastatic adenocarcinoma from the gallbladder.
Interventions: The patient received chemotherapy with gemcitabine and cisplatin instead of surgery,however,after six cycles, the lesion increased after reexamination, so the treatment was changed to combination with duvariumab regimen for 5 cycles.
Outcomes:At present, the treatment process went smoothly with no recurrence or obvious progress during follow-up.
Conclusions: Differential diagnosis between primary and metastatic ovarian tumors is important.Early diagnosis and effective treatment options are essential for patient survival.The punch biopsy is significant for patients with multiple metastases that cannot tolerate surgery.
Ethical compliance: All procedures performed in studies involving human participants comply with the ethical standards of the institutional and / or national research committees and with the 1964 Helsinki Declaration and its later amendments or similar ethical standards.
Data Access Statement: The research data supporting this publication is available from the NN repository at www.NNN.org/download/
Estimation of Heterogeneous Population Variance using Memory-type Estimators based on EWMA statistic in the presence of Measurement Error for Time-Scaled Surveys
Authors: Qureshi Muhammad Nouman , Tariq Muhammad Umair , Xiong Yeng , Hanif Muhammad 
Published: February 2023

Abstract

In this present article, we have suggested memory-type ratio, exponential ratio, product and exponential product estimators based on exponentially weighted moving average statistic for the estimation of heterogeneous population variance using stratified sampling design in presence of measurement error for time-scaled surveys. Mathematical expressions of approximate mean square error are derived using Taylor and exponential expansions for the proposed memory-type estimators. We have also discussed the situations in which the memory-type estimators would perform efficiently than the conventional estimators. The results of extensive simulation study revealed that the proposed memory-type estimators based exponentially weighted moving average statistic would perform better than the conventional estimators in the presence measurement error for time-scaled surveys under certain condition.
Perceptions and motivations for healthy lifestyles among first-degree relatives of colorectal cancer patients: A qualitative study
Authors: Wang Wenxia , Fang Shuyan , Zhang Shuang , He Meng , Zhu Xiangning , Dong Yueyang , Ma Dongfei , Zhao Yanjie , Meng Xiangfei , Gao Shizheng , Zhi Shengze , Sun Juanjuan , Song Dongpo , Sun Jiao 
Published: February 2023

Abstract
Background
Compelling data indicate that adherence to healthy lifestyles can potentially prevent 20–70% of colorectal cancer (CRC) cases and deaths. As a major population in the development of CRC, the lifestyle behaviour of first-degree relatives (FDRs) of CRC patients is attracting more attention.
Objective
To understand the knowledge of first-degree relatives (FDRs) about colorectal cancer (CRC) and healthy lifestyles and explore their perceptions of and motivations for healthy lifestyles for CRC prevention.
Methods
A qualitative descriptive study using inductive thematic analysis was performed. Sixteen FDRs of CRC patients were recruited using purposive sampling. Face-to-face semi-structured interviews were conducted to gain insight into FDRs’ perceptions and motivations regarding healthy lifestyles for CRC prevention.
Results
Limited knowledge of CRC makes FDRs less likely to emphasise the prevention of CRC through a healthy lifestyle. Influenced by the culture of Chinese medicine and life experience, the participants gradually developed a perception of healthy lifestyles with Chinese characteristics. The participants’ ability to maintain a healthy lifestyle was greatly influenced by family duty-related factors.
Conclusions
Social culture and family duty-related factors should be taken into consideration when undertaking health interventions or education programmes on healthy lifestyles for FDRs of CRC patients. Encouraging nurses to act as liaisons between the government, hospitals, and the community and providing them with professional and communication skills to enhance their skills has great potential for nurses to deliver health education and management for communities at risk of CRC.
The role of lysosomal membrane stability, malondialdehyde levels and DNA damage as pollution biomarkers of terrestrial environments using Eobania vermiculata
Authors: Aikaterini Itziou 
Published: February 2023

Abstract
The current work investigates the role of neutral red retention assay, malondialdehyde contents and DNA damage through comet assay as biomarkers of terrestrial environmental pollution using the land snail Eobania vermiculata. Snails were collected near a lignite power station located about 6 km near the city of Ptolemaida in the district of Kozani. The results of the study showed significantly lower neutral red retention times, higher malondialdehyde contents and higher formation of single-stranded DNA fragments in the haemolymph of snails collected from the polluted area compared to control animals. In support of our data, the values of pollution biomarkers showed significant correlations, thus encouraging their use in terrestrial pollution biomonitoring studies and highlighting the effects of pollution in terrestrial environments.
Influence on the Magnetic Field on the Scale Formation in a Microfluidic Channel under A Low Reynolds Number Flow
Authors: Huang Chiung-Yi , Lin Che-Hsin 
Published: February 2023

Abstract

This study presents an external magnetic array to rapidly investigate the calcium carbonate formation in a microfluidic channel. The system was made by a copper coil capillary as the heat exchanger, a high-precision thermostatic water tank, a magnetic drive pump, and an external magnetic array. Different concentrations (3 mM and 10 mM), magnetic treated efficiency (magnet length 4.0 cm and 14.0 cm, treatment time 24 hr and 72 hr), and temperature (25oC to 50oC) of test solution were discussed during the experiment. The concentration of calcium ion, electrical conductivity, and pH value were measured to record the subtle change during water treatment. In addition, the SEM and the XRD were used to analyze the particle size distribution and morphology of calcium carbonate under different magnetic treatments. As the results of the experiments, (1) the particle size of calcium carbonate decreased when a magnetic field was applied to the solution in a microfluidic channel under a low Reynolds number flow, (2) the aragonite didn’t appear in the microfluidic channel, and (3) the physicochemical properties of the solution weren’t altered by the magnetic treatment. Consequently, the small particle size can inhibit microchannel from blocking, and the outcome of this study provides an alternative method to minimize the scale problem in micro heat exchangers.
Automatic apraxia detection using Deep Convolutional Neural Networks and similarity methods
Authors: Bringas Santos , Nieto-Reyes Alicia , Vicedo Cristina , Duque Rafael , Lage Carmen , Montaña José Luis 
Published: February 2023

Abstract
Dementia represents one of the great problems to be solved in medicine for a society that is becoming increasingly long-lived. One of the main causes of dementia is Alzheimer’s disease, which accounts for 80% of cases. There is currently no cure for this disease, although there are treatments to try to alleviate its effects, which is why detecting Alzheimer’s disease in its early stages is crucial to slow down its evolution and thus help sufferers. One of the symptoms of the disease that manifests in its early stages is apraxia, difficulties in carrying out voluntary movements. In the clinical setting, apraxia is typically assessed by asking the patient to imitate hand gestures that are performed by the examiner. To automate this test, this paper proposes a system that, based on a video of the patient making the gesture, evaluates its execution. This evaluation is done in two steps, first extracting the skeleton the skeleton of the hands and then using a similarity function to obtain an objective score Automatic apraxia detection using Deep CNNs and similarity methods of the execution of the gesture. The results obtained in an experiment with several patients performing different gestures are shown, showing the effectiveness of the proposed method. The system is intended to serve as a diagnostic tool, enabling medical experts to detect possible mobility impairments in patients that may be signs of Alzheimer’s disease.
Decentralized Classification in Sensor Networks via Sparse Representation and Constrained Fractional Programming
Authors: Ye Zhonghua , Zhu Hong , Fang Xueyi 
Published: February 2023

Abstract
This paper investigates the problem of decentralized classification algorithm in sensor networks, i.e., the data about the agriculture are sensitive (or private) stored in the sensor network nodes without sharing or collecting them together. The contributions of this paper are: i) two new classification algorithms are proposed based on the sparse representation and constrained fractional programming. One is for the centralized environment while the other is for the decentralized environment, where the decentralized network node is able to process its own data to extract useful information by implementing some local computation, communication, and storage operations. Especially, by collaborating with its neighbors, it can achieve the same classification result compared with that of the centralized algorithm; ii) to reduce the redundance of the original data, we form a new classification strategy by combining the sparsity transform with the classifier; iii) to improve the robustness of the classifiers, we construct a constrained fractional programming to enforce the discriminant ability of the classifier so that the transformed coefficient vector should be closer to the class center of itself but being far away from centers of other class; iv) to handle the proposed centralized/decentralized classification problems, we decouple the constrained fraction via the Dinkelbach algorithm and alternating minimization. Especially, we cast the decentralized classification problem as a set of subproblems with consensus constraints so that it can be solved in the network environment via the inherent information communication and local computation ability of alternating direction method of multiplier. Finally, numerical examples are provided to verify the effectiveness of the proposed algorithms.
MYD88L265P and MYD88other variants show different molecular characteristics and prognostic significance in diffuse large B-cell lymphoma
Authors: Qin Yan , Qiu Tian , Xie Zucheng , Chen Xinrui , Liu Peng , Yang Jianliang , He Xiaohui , Gui Lin , Zhou Shengyu , Jiang Hongxin , Zhang Changgong , Yang Sheng , Tang Le , Shi Yuankai 
Published: February 2023

Abstract
Purpose
This study aims to investigate the clinical and molecular differences between diffuse large B-cell lymphoma (DLBCL) patients with MYD88L265P and MYD88other.
Methods
DLBCL patients with MYD88 variations were collected from the Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College (CHCAMS), and Suzhou Municipal Hospital from February 6th, 2007 to May 20th, 2022. Clinicopathological parameters and treatment outcomes between MYD88L265P and MYD88other were investigated.
Results
A total of 132 patients with MYD88 variations from a cohort of 475 DLBCL patients were included, among which, 78 were MYD88L265P, while 54 were MYD88other. MYD88L265P was more common in non-GCB subtype than MYD88other (83% vs. 60%, P = 0.004). Besides, MYD88L265P was significantly related to higher proportion of testicle/ central nervous system involvement (31% vs. 6%, P < 0.001), PIM1 mutation (71% vs. 39%, P < 0.001), and PIM1 hypermutation (28% vs. 11%, P = 0.018), compared with MYD88other. Compared with MYD88L265P, MYD88other were more likely to have higher percentage of advanced stage (60% vs. 42%, P = 0.044), extranodal site ≥ 2 (45% vs. 28%, P = 0.044), elevated LDH (55% vs. 35%, P = 0.033), positive CD10 expression (36% vs. 16%, P = 0.009), BCL-6 translocation (20% vs. 8%, P = 0.033), and NOTCH pathway gene alteration (24% vs. 13%, P = 0.040). In non-GCB DLBCL subtype, patients with MYD88other were significantly associated with worse PFS than those with MYD88L265P (P = 0.010).
Conclusion
The findings of this study indicate that DLBCL patients with MYD88L265P and MYD88other are likely to be two subgroups with different clinical and molecular characteristics. The survival of patients with MYD88other is not superior than those with MYD88L265P, even poorer when focusing on the non-GCB subtype.
Correction to: There is at most one continuous invariant mean
Authors: Boros Zolt\'an , Lovas Rezső L. , Pasteczka Paweł 
Published: February 2023

Abstract
A mistake in the formulation of Lemma~1 has been corrected. A preliminary section to the proof of Theorem~1 is added.
Mathematics Subject Classification (2010). Primary 26E60, Secondary 39B12, 39B22.
Altruistic behavior and International Environmental Agreements
Authors: Sacco Armando 
Published: February 2023

Abstract
In the last three decades International Environmental Agreements (IEAs) has been widely analyzed. Classical models predict that only coalitions formed by few countries can be stable, generating a rich literature devoted to solve the small coalition puzzle. The fundamental idea behind the great part of the literature is that players are selfish: to achieve a large stable coalition it is necessary to design an agreement that include a credible system of incentives or punishment.
The aim of this model is to study the effects on equilibrium strategies and on the stability of an IEA when players do not look at their on interests only, but they take care of the wellness of the other players in coalition. Following the approach of the Paris Agreement in 2015, countries that join the coalition do not decide the emission collectively, but each country sets its own emission. The model is the usual two-step game: first the players has to choose if they want to join the coalition or not, in the second step they solve a Nash differential game to find the optimal emissions. The stability of the coalition is studied in two cases: i) with the classic internal and external stability, ii) defining an altruistic stability condition.
The Move From Fujita Type Exponent to a Shift of It for a Class Of semilinear Evolution Equations With Time-dependent Damping
Authors: Ebert Marcelo Rempel , Marques Jorge , NASCIMENTO Wanderley NUNES DO 
Published: February 2023

Abstract
Note: Please see pdf for full abstract with equations.
In this paper, we derive suitable optimal Lp−Lq decay estimates, 1 ≤ p ≤ 2 ≤ q ≤ ∞, for the solutions to the σ-evolution equation, σ > 1, with scale-invariant time-dependent damping and power nonlinearity |u|p,
utt + (−Δ)σu + μ/1 + t ut = |u|p, t ≥ 0, x ∈ Rn,
where μ > 0, p > 1. The critical exponent p = pc for the global (in time) existence of small data solutions to the Cauchy problem is related to the long time behavior of solutions, which changes accordingly μ ∈ (0, 1) or μ > 1. Under the assumption of small initial data in Lm(Rn) ∩ L2(Rn),m = 1, 2, we find the critical exponent at low space dimension n with respect to σ, namely,
pc = max {¯p(γm), ¯p(γm + μ − 1)}, γm :=n/mσ, μ > 1 − γm,
where ¯p(γ) := 1+ 2/γ is the well known Fujita exponent. Hence, pc = ¯p(γm) if μ > 1, whereas pc = ¯p(γm +μ−1) is a shift of Fujita type exponent if μ ∈ (0, 1).
2010 Mathematics Subject Classification. 35L15, 35L71, 35A01, 35B33, 35E15, 35G25.
A New Method for Calculating the Inductance of Planar Spiral Square Coils Used in Wireless Power Transfer
Authors: Cetin Ramazan , Agcal Ali 
Published: February 2023

Abstract
The planar spiral square coil (PSC) is one of the most common structures used in wireless power transfer (WPT) applications. In this paper, a new self-inductance calculation method is proposed for PSC. The self-inductance of the coil should be calculable in order to comprehend the interaction between the coil and the WPT system. In this paper, A new self-inductance calculation method for PSC is proposed by using Greenhouse's method of calculating the inductance between the conductors. The proposed new greenhouse method has been tested for various square sizes, spaces between conductors, the number of turns, and conductor widths. Also, the proposed new method was compared with Current sheet method, modified Wheeler method, and Ansys Maxwell 3D simulation results in terms of calculation error rate. The self-inductance calculation error rate of this method was lower than in all other studies and was below 0.4% in all cases.
Synergetic Antibacterial Activity of CuO-Ag Janus Like Nanoparticles
Authors: Fomina Marina , Sizova Elena , Nechitailo Кseniya 
Published: February 2023

Abstract
This work provides a comparative evaluation of the antibacterial activity of CuO-Ag Janus particles and a bicomponent mixture of CuO and Ag particles against a recombinant strain Escherichia coli K12 TG1 with cloned luxCDABE genes of marine bacteria Photobacterium leiognathi 54D10. An original method for the preparation CuO-Ag nanoparticles by simultaneous electrical explosion of twisted Cu and Ag wires in a mixture of argon and oxygen gases was used. The CuO-Ag Janus nanoparticles have been found to be the most bioactive with respect to the studied biosensor, causing 50% inhibition of bioluminescence (EC50 = 0.03 ± 0.001 mg/ml) (p < 0.05). At the same time, an order of magnitude less pronounced inhibitory effect was observed with CuO particles doped with 70 nm silver nanoparticles (EC50 = 0.25 ± 0.002 mg/ml) (p < 0.05). Against this background, the nominal toxicity values of CuO and Ag as monocomponent nanoparticles were 2–32 times lower compared with the bicomponent nanoparticles. A dose-dependent inhibition of bacterial luminescence developed over time was noted. Thus, as a result of the contact of E. coli with CuO-Ag Janus particles, 100% suppression of bacterial luminescence from the first minutes of contact occured, starting with a content of 2.0 mg/ml, and within the next 180 minutes, the effect of bioactivity prolonged in the final concentration of nanopowder (EC100 = 0.0625 ± 0.002 mg/ml) (p < 0.05). CuO-Ag Janus particles exhibit more pronounced antibacterial activity compared to CuO, Ag nanoparticles and their mechanical mixture.
Identification of Potential Biomarkers for Nonsurvivor Sepsis Patients via Microarray Technology: A Study Based on GEO Datasets
Authors: Ma Yan , Shan Shichao , Luo Cheng , Mo Jianlan , Hu Zhaokun , Jing Ren 
Published: February 2023

Abstract
Background: The mechanism of sepsis especially non-survivors has not yet been identified.
Objective: To identify the key genes concerned with non-survivor sepsis (NSS) and analyze its molecular mechanism.
Methods: The original data were obtained from the GEO database and then screened deferentially expressed genes (DEGs). GO and KEGG analysis were performed to analyze the functional annotation of DEGs. The protein‑protein interaction (PPI) network and related analysis of hub genes were then carried out. Further, potential hub genes were confirmed in the lipopolysaccharide (LPS)-induced septic mice by western blotting and immunohistochemistry.
Results: we obtained 188 DEGs and 32 hub genes between NSS patients and healthy volunteers. Among of them, the top 10 hub genes including STAT1, ISG15, HERC1, EIF2AK2, RPL27, LY6E, IFI44L, XAF1, RSAD2 and HERC6 were studied, which predict sepsis based on receiver operator characteristic curve analysis. GO analysis found that these hub genes were enriched in positive regulation of biomedical process including translation, response to virus and suppression of mitochondrial depolarization, etc.;cell component including mitochondrial inner membrane; molecular function containing ligase activity, etc. The KEGG pathway analysis showed that these hub genes are obviously enriched in influenza A infection and leukocyte trans-endothelial migration. Furthermore, 20 mg/kg of LPS injection up-regulated the expression of ISG15, RPL27, LY6E and HERC6 in the lung tissues compared with control mice.
Conclusion: These identified 188 DEGs and 10 hub genes were associated with NSS, especially ISG15, RPL27, LY6E and HERC6 genes expressed in the lung as the most vulnerable organ.
The importance of environmental and disturbance conditions in different growth stages of plants of temperate forest in the Sierra Norte of Oaxaca, Mexico
Authors: Gutiérrez Erick , Flores-Galicia Nihaib , Trejo Irma 
Published: February 2023

Abstract
Environmental conditions and disturbances are important factors that could influence ecological processes. For this reason, it is essential to know the relationship between them. The objective of this study was to analyze the effect of environmental conditions and disturbance on three growth stages (adults, germinated individuals, and seeds) of conifers, oaks, and other broadleaf species that compose the temperate forests of the highlands of the Sierra Norte of Oaxaca, Mexico. For this purpose, we established 0.1 ha plots along an altitudinal gradient ranging from 1950 m to 3250 m asl where we sampled vegetation, placed traps for seed rain, and quantified seed germination. We recorded climatic, edaphic, topographic, light, and disturbance conditions. We recorded a positive influence of anthropogenic disturbances on conifers in all their growth stages analyzed. For oaks and other broadleaf species, climatic variables such as temperature and precipitation showed a negative effect on adults and seeds, while disturbance showed no effect. Our results indicate that environmental conditions and anthropogenic disturbances have a differential effect on the biological groups that compose these forests and depending on the growth stage of the biological groups.