bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of linewidth enhancement factor of laser diode and fiber dispersion management on high-speed optical fiber links performance and use in WDM systems
Authors: Mahmoud Alaa , Fouad Nada , Ahmed Moustafa , Mohamed Tarek 
Published: January 2023

AbstractWe present a numerical simulation study on the effect of the linewidth enhancement factor (α) of semiconductor laser and dispersion management methods of optical fibers on the performance of 40-Gb/s directly-modulated fiber links and their application in WDM systems. The dispersion management methods include the use of non-zero dispersion-shifted fiber (NZ-DSF), dispersion-compensating fiber (DCF), and fiber Bragg grating (FBG). The optimal values of the α-parameter and the best dispersion management method are applied to design and simulate a four-channel × 40-Gb/s WDM fiber system. The obtained results show that the increase in the α-parameter and/or fiber length reduces the performance of both the 40-Gb/s optical link and the WDM system. Regarding the 40-Gb/s optical link, when α = 1, using –NZ-DSF or + NZ-DSF, DCF with SSMF, and FBG with SSMF work to increase the transmission length from 1.6 km of a standard single-mode fiber (SSMF) to 7.2, 26.5, and 40 km, respectively. Whereas at α = 3.5, the maximum transmission length reaches 1.2 km when using SSMF, –NZ-DSF, or + NZ-DSF, while it increases to 13 and 35 km when using DCF with SSMF, and FBG with SSMF, respectively. In the designed WDM system, the use of FBG with SSMF is predicted as the most effective method for dispersion management. The maximum transmission length reaches 25 km when α = 1, but reduces to 12 km when α = 3.5.
Steady-State Two-Phase Flow of Compressible and Incompressible Fluids in a Capillary Tube of Varying Radius
Authors: Cheon Hyejeong L. , Fyhn Hursanay , Hansen Alex , Wilhelmsen Øivind , Sinha Santanu 
Published: January 2023

AbstractWe study immiscible two-phase flow of a compressible and an incompressible fluid inside a capillary tube of varying radius under steady-state conditions. The incompressible fluid is Newtonian and the compressible fluid is an inviscid ideal gas. The surface tension associated with the interfaces between the two fluids introduces capillary forces that vary along the tube due to the variation in the tube radius. The interplay between effects due to the capillary forces and the compressibility results in a set of properties that are different from incompressible two-phase flow. As the fluids move towards the outlet, the bubbles of the compressible fluid grows in volume due to the decrease in pressure. The volumetric growth of the compressible bubbles makes the volumetric flow rate at the outlet higher than at the inlet. The growth is not only a function of the pressure drop across the tube, but also of the ambient pressure. Furthermore, the capillary forces create an effective threshold below which there is no flow. Above the threshold, the system shows a weak nonlinearity between the flow rates and the effective pressure drop, where the nonlinearity also depends on the absolute pressures across the tube.
Anti-Skepticism Under a Linguistic Guise
Authors: Grindrod Jumbly 
Published: January 2023

AbstractIn this paper I consider the plausibility of developing anti-skepticism by framing the question in linguistic terms: instead of asking whether we know, we ask what falls within the extension of the word “know”. I first trace two previous attempts to develop anti-skepticism in this way, from Austin (particularly as presented by Kaplan) and from epistemic contextualism, and I present reasons to think that both approaches are unsuccessful. I then focus on a recently popular attempt to develop anti-skepticism from the “function-first” approach associated with Craig, which I also show to be problematic. I then argue that the apparentprima facieplausibility of fighting skepticism on linguistic grounds is due to a methodological spill-over from linguistics. Once we recognize this, it becomes clear that the skepticism debate should not be conducted in linguistic terms.
Engaging with Colonial Knowledge on African Associational Life: Angola Case Study from 1860 to 1974
Authors: Dias Pereira Joana 
Published: January 2023

AbstractDespite growing interest in African civil society and the enduring legacy of colonialism, studies on this theme with a historical perspective are still few. This article analyses the evolution of associational life in Luanda from its origins in the mid-nineteenth century until the decolonisation in 1974. It is based on a complete census of the officially recognised bylaws, which confirmed that formal associationism was exclusive to settlers and a minority of ‘assimilated’ natives. Modern associations among the ‘detribalised’ urban populations, never recognised by the colonial authorities, were considered by analysing ethnographic research. Historical empirical evidence sustains the idea that the colonial encounter determinately shaped civil society and the public sphere, determining the inequality in access and exercise of citizenship while illustrating the strategies used by native people to overcome legal and political constraints to associationism.
Cyclic Superelastic Behavior of Iron-Based Fe-Ni-Co-Al-Ti-Nb Shape Memory Alloy
Authors: Lauhoff C. , Remich V. , Giordana M. F. , Sobrero C. , Niendorf T. , Krooß P. 
Published: January 2023

AbstractIron-based shape memory alloys came into focus as promising candidate materials for large-scale structural applications owing to their cost-efficiency. In the present work, the superelastic properties of a recently introduced Fe-Ni-Co-Al-Ti-Nb shape memory alloy are investigated. For 〈001〉-oriented single-crystalline material in aged condition (650 °C/6 h), an incremental strain test reveals excellent superelasticity at −130 °C with fully reversible strains up to about 6%. Under cycling loading at different test temperatures, however, the alloy system investigated suffers limited functional stability.
Evaluation of aerial vehicle configurations for high-range Mars missions
Authors: Zappek Victor , Rinker Markus , Daxer Lukas , Hajek Manfred 
Published: January 2023

AbstractAs part of an envisioned autonomous swarm exploration mission in Valles Marineris on Mars a design investigation of a high-range scout UAV is performed in this work. Two VTOL configurations, a coaxial helicopter and a transition tailsitter, are examined to assess their suitability. A preliminary design framework using Python and the optimization framework OpenMDAO is created using the preliminary design software NDARC. To model the rotor performance, comprehensive analysis simulations are executed using CAMRAD II. Structural 2D-FEM beam models are created for the rotor blades and the wing for weight modeling. Design sizings are executed for operation in the extremely thin atmosphere and the mission performance for a scouting mission as part of the robotic Valles Marineris Explorer (VaMEx) swarm is examined. A behavioral model is created to evaluate the controllability of the configurations. The results for a mission with a cruise flight of 30 km and 1.4 kg of payload show that for such a mission the transition configuration does not offer advantages over a more conventional coaxial helicopter design. To understand design sensitivities and to evaluate the respective effects on vehicle performance parameter sweeps are conducted.
Catalpol Mitigates Alzheimer's Disease Progression by Promoting the Expression of Neural Stem Cell Exosomes Released miR-138-5p
Authors: Meng Shengxi , Chen Huize , Deng Chunjun , Meng Zeyu 
Published: January 2023

AbstractAlzheimer’s disease (Alzheimer’s disease, AD) is a neurodegenerative disease characterized by senile plaque deposition and neurofibrillary tangles. The pathogenesis of AD is complicated and the drugs used to treat AD are single-targeted drugs, which can only improve or alleviate the symptoms of patients, but cannot delay or prevent the progress of the disease. Because of its ability to act on multiple targets, multiple systems, multiple links, and multiple pathways, Chinese herbal compound prescriptions have shown unique advantages in the research and treatment of AD. Our previous study has demonstrated the protect role of the Chinese medicine Rehmannia in AD. However, the underlying mechanism remains unclear. In the present study, both in vitro and vivo experiments were employed, and we found Catalpol (Ca), the main extract of Rehmannia, could mitigate AD progression both in vitro and in vivo by promoting miR-138-5p level in neural stem cell secreted exosomes
Untargeted metabolomics to evaluate antifungal mechanism: a study of Cophinforma mamane and Candida albicans interaction
Authors: Triastuti Asih , Vansteelandt Marieke , Barakat Fatima , Amasifuen Carlos , Jargeat Patricia , Haddad Mohamed 
Published: January 2023

AbstractMicrobial interactions between filamentous fungi and yeast are still not fully understood. To evaluate a potential antifungal activity of a filamentous fungus while highlighting metabolomic changes, co-cultures between an endophytic strain of Cophinforma mamane (CM) and Candida albicans (CA) were performed. The liquid cultures were incubated under static conditions and metabolite alterations during the course were investigated by ultra-performance liquid chromatography–tandem mass spectrophotometry (UPLC–MS/MS). Results were analyzed using MS-DIAL, MS-FINDER, METLIN, Xcalibur, SciFinder, and MetaboAnalyst metabolomics platforms. The metabolites associated with catabolic processes, including the metabolism of branched-chain amino acids, carnitine, and phospholipids were upregulated both in the mono and co-cultures, indicating fungal adaptability to environmental stress. Several metabolites, including C20 sphinganine 1-phosphate, myo-inositol, farnesol, gamma-undecalactone, folinic acid, palmitoleic acid, and MG (12:/0:0/0:0) were not produced by CA during co-culture with CM, demonstrating the antifungal mechanism of CM. Our results highlight the crucial roles of metabolomics studies to provide essential information regarding the antifungal mechanism of C. mamane against C. albicans, especially when the lost/undetected metabolites are involved in fungal survival and pathogenicity.
Graphical Abstract
Effect of glucagon-like peptide-1 receptor agonist on insulin secretion index and serum Wnt5a protein in patients with new-onset type 2 diabetes mellitus
Authors: Xu Wei , Sang Y. Q. , Liu X. K. , Geng H. F. , Wang Ben , Shi Li , Qiu Q. Q. , Yu T. P. , Zhang Yan , Zhang Xia , Li Lin , Li Qing , Liang Jun 
Published: January 2023

AbstractObjectivePrevious studies have found that wnt5a promotes β-cell insulin secretion and reduced concentrations in patients with type 2 diabetes. GLP-1RA (Glucagon-like peptide-1 receptor agonists) can regulate insulin secretion. However, the evidence that GLP-1RA affect insulin secretion through the Wnt5a is inconclusive. Therefore, this study aimed to evaluate the effect of GLP-1 RA on wnt5a levels in patients with type 2 diabetes.MethodsA total of 56 onset diabetics were selected our study, 29 of them were treated by GLP-1RAs (1.2mg subcutaneous injection once a day, liraglutide, Novo Nordisk), the rest (27 case) treated by Metformin (0.5 g twice a day, Glucophage, Merck). Individuals who were using medications to manage platelet (Aspirin) and cholesterol (Statins) were enrolled and continued treatment throughout the study.ResultsOur study found that the waist circumference and insulin secretion index in the GLP-1RA intervention group were significantly increased, and the insulin resistance index was lower than that of the control group. More interestingly, the serum Wnt5a protein level increased dramatically after the GLP-1RA intervention, and the level of Secreted frizzled-related protein 5 (Sfrp5) decreased compared with the control group. Multivariate linear regression analysis showed that the change of HOMA-β (Homeostasis model assessment- β) was significantly correlated with the changes of Wnt5a and Sfrp5, and the change of Wnt5a protein was positively correlated with HOMA-β.ConclusionOur results confirmed that GLP-1RA may improve HOMA-β in patients with type 2 diabetes by affecting the level of Wnt5a protein.
Semi-Empirical Astronomical Light Pollution Evaluation of Satellite Constellations
Authors: Hall Doyle T. 
Published: January 2023

AbstractSeveral commercial organizations have recently launched or plan to launch constellations containing thousands of satellites. Such large constellations potentially adversely affect astronomical observations. This study formulates a set of indicators that assess the impact of light pollution from different constellations on ground-based visible band astronomy. These include the statistically expected number of visible and sunlit satellites above ground-based observers, as well as the number that are also expected to be brighter than the currently recommended limit for constellation satellites. The latter indicator provides a consolidated means to evaluate the potential for a constellation to affect ground-based astronomy too severely, by simultaneously accounting for the effects of constellation population, orbital distribution as well as brightness magnitude and variability. For existing constellations, the evaluation process incorporates actual satellite photometric brightness measurements, which are becoming increasingly available in web-accessible databases and repositories. For proposed constellations, a semi-empirical method allows rough approximations of pre-launch light pollution levels, based on observed brightness distributions observed of currently orbiting analog satellites.
On GVC and innovation: the moderating role of policy
Authors: Eissa Yasmine , Zaki Chahir 
Published: January 2023

AbstractThis paper empirically investigates the association between global value chains (GVC) participation and countries’ innovation performance. Highlighting the learning effect of foreign knowledge embedded in imported intermediate goods counters the argument that GVC participation is biased towards developed countries with skilled labor abundance. We construct a GVC knowledge spillovers index by merging data on GVC from the EORA26 dataset with R&D of the trade partner. Results show positive association between the GVC knowledge spillovers index and innovation measured by resident patent per capita. Likewise, we show that trade policy, intellectual property rights’ agreements, and competition policy constitute moderating factors in the nexus between GVC participation and innovation. Our results remain robust when we use alternative measures for our two variables of interest and when we control for foreign knowledge spillovers in imported final goods.
Coupling Effects of Potassium Fertilization Rate and Application Time on Growth and Grain Yield of Wheat (Triticum aestivum L.) Plants Grown Under Cd-Contaminated Saline Soil
Authors: El-Mageed Taia A. Abd , Semida Wael M. , Abdou Nasr M. , El-Mageed Shimaa A. Abd 
Published: January 2023

AbstractPotassium is an essential macronutrient, where its availability regulates numerous biochemical, phenological, and physiological responses in plants. Synchronizing potassium supply with plant demand is a key factor to enhance growth and grain production of wheat grown in cadmium-contaminated saline soils. Field experiments were conducted in El Fayoum province, Egypt, between latitudes 29° 02′ and 29° 35′ N and longitudes 30° 23′ and 31° 05′ E, during the cropping seasons of 2017–2018 and 2018–2019 to determine the influence of different applied potassium rates and times on nutrient uptake and wheat yield grown under Cd-contaminated saline soil (ECe = 8.53 dS m−1and Cd = 18 mg kg−1soil). Four K levels (K0, K40, K80, and K120representing 0, 40, 80, and 120 kg ha−1) were applied at different application times [full dose (basal) at sowing (100% S), two equal split doses at sowing and flowering stage (50% S + 50% F), and full dose at flowering stage (100% F)]. The experimental treatments were arranged in a randomized split complete block design and replicated three times. The applied K rates, times, and their interaction induced significant differences in nutrient uptake and physiological responses which in turn improved the growth and yield of the wheat crop. Potassium addition with 120 kg ha−1at two equal split doses (50% S + 50% F) resulted in the highest values of plant height (97 cm), Fv/Fm (0.83), PI (5.49), SPAD (58.63), MSI (34.57), seed yield (5.04 t ha−1), straw yield (9.04 t ha−1), and water productivity (0.99 kg m−3). Similarly, the uptake of N, P, K, Ca, Mg, Fe, Mn, and Zn was increased, while the uptake of Na and Cd decreased as the K supply increased under the split application. The addition of potassium by 120 kg ha−1in two equal split doses at the sowing and flowering stage could be a valuable approach to improve yield and yield quality of wheat crop grown under cadmium-contaminated saline soils.
Role and Clinical Significance of Monocarboxylate Transporter 8 (MCT8) During Pregnancy
Authors: Thomas Jinsu , Sairoz  , Jose Anmi , Poojari Vidyashree G. , Shetty Sahana , K Shama Prasada , Prabhu R V Krishnananda , Rao Mahadev 
Published: January 2023

AbstractThe review aims to summarize the available research focusing on the importance of monocarboxylate transporter (MCT8) in thyroid hormone trafficking across the placenta and fetal development. A systematic search was carried out in PubMed; studies available in English related to “monocarboxylate transporter”, “adverse pregnancy”, “fetal development,” and “thyroid hormone” were identified and assessed. The references within the resulting articles were manually searched. MCT8 is a highly active and selective thyroid hormone transporter that facilitates the cellular uptake of triiodothyronine (T3), thyroxine (T4), reverse triiodothyronine (rT3), and diiodothyronine (T2) in different tissues. MCT8 is expressed in the placenta from the first trimester onwards, allowing the transport of thyroid hormone from mother to fetus. Mutations in MCT8 cause an X-linked disorder known as Allan-Herndon-Dudley syndrome (AHDS), characterized by severe psychomotor impairment and peripheral thyrotoxicosis. Hence, any maternal thyroid dysfunction may cause severe consequences for the fetus and newborn. Further research regarding MCT8 gene expression, polymorphic variation, and adverse pregnancy outcomes must be done to establish that MCT8 is a novel prognostic marker for the early detection of pregnancy-related complications.
A strengthened Orlicz–Pettis theorem via Itô–Nisio
Authors: Sussman Ethan 
Published: January 2023

AbstractIn this note, we deduce a strengthening of the Orlicz–Pettis theorem from the Itô–Nisio theorem. The argument shows that given any series in a Banach space which is not summable (or more generally unconditionally summable), we can construct a (coarse-grained) subseries with the property that—under some appropriate notion of “almost all”—almost all further subseries thereof fail to be weakly summable. Moreover, a strengthening of the Itô–Nisio theorem by Hoffmann–Jørgensen allows us to replace ‘weakly summable’ with ‘$$\tau$$
τ
-weakly summable’ for appropriate topologies $$\tau$$
τ
weaker than the weak topology. A treatment of the Itô–Nisio theorem for admissible $$\tau$$
τ
is given.
Petrology of Palaeoarchaean mafic–ultramafic rock suites of the western Iron Ore Group, Singhbhum Craton, eastern India, using the chemistry of minerals
Authors: Paul Madhuparna , Ray Jyotisankar , Koeberl Christian , Patel Suresh C. , Sheikh Janisar M. , Manikyamba C. , Gayen Moumita , Bhattacharjee Nibedita 
Published: January 2023

AbstractThe petrogenesis of Palaeoarchaean mafic–ultramafic rock suites from the western Iron Ore Group, Singhbhum Craton, eastern India, has been evaluated based on the chemistry of constituent mineral phases. The rock suites include basaltic rocks and mafic (gabbro) to ultramafic (serpentinized peridotite) intrusive rocks, which occur in host rocks covering phyllite, ferruginous shale, banded haematite quartzite and jasper. The constituent clinopyroxene shows dominant uralitization, whereas plagioclase grains are generally saussuritized, being marked by relatively tiny granular aggregates of albite, chlorite, epidote and K-feldspar. The ultramafic intrusive rocks are overwhelmingly serpentinized. Clinopyroxene compositions are augitic, whereas relict plagioclase is typically bytownite. Amphiboles of the investigated rock suites are divisible into the ‘uralite’ type (occurring peripherally to clinopyroxene) and the ‘completely changed-over amphibole’ type (with no traces of initial clinopyroxene). Both the amphibole types belong to the ‘calcic group’, showing a compositional spectrum from actinolite–magnesiohornblende–ferrohornblende–ferroactinolite. Opaque minerals include magnetite (both Cr-magnetite and Al-magnetite), chromite (Al-chromite) and ilmenite, whereas serpentine (belonging to the ultramafic intrusive rocks) corresponds to lizardite. Looking at the mineral compositions of the pyroxene, glass and amphibole, the studied rock suites show a wide equilibration temperature–pressure domain range (∼750 °C to ∼1400 °C at ∼0.26 kbar to ∼21 kbar), which corresponds to an ascending magma that underwent a ‘hydration event’ at a shallow level. The assessment of the clinopyroxene and spinel chemistry characteristically suggests an arc setting for the parent magma that has undergone both equilibrium and fractional crystallization in the course of magmatic evolution. During differentiation, the magmatic density remains almost constant, with variable oxygen fugacity.
IL GOVERNO ELETTRONICO: VISIONI, PRIMI RISULTATI E UN'AGENDA DI RICERCA
Authors: Calise Mauro , De Rosa Rosanna 
Published: January 2023

IntroduzioneSul governo elettronico (e-government per gli addetti ai lavori) pesa, dalle origini, un'ambivalenza — e ambiguità. Terminologica ma, al tempo stesso, politologica. Nella quasi totalità degli studi, sia di presentazione che di implementazione, l'e-government viene indicato come un processo di trasformazione tecnologica (più o meno radicale) di alcune prassi amministrative, con l'obiettivo principale (dichiarato) di rendere più trasparente, efficiente e interattiva l'erogazione di alcuni servizi e l'accesso a molte informazioni. In tale accezione, l'e-government si collocherebbe tra i processi di ammodernamento della macchina burocratica rientrando nell'affollata categoria dei tentativi di riforma della pubblica amministrazione. Coerentemente con tale impostazione, numerose definizioni sottolineano l'ambito strettamente implementativo e policy-oriented dei principali progetti di e-government, collegandoli — e condizionandoli — alle potenzialità tecnologiche offerte dallo sviluppo delle ICT e di Internet in particolare.
UNA BIOGRAFIA INTELLETTUALE E DI VITA DEL «MAESTRO-COMPOSITORE» JUAN J. LINZ
Authors: Schmitter Philippe 
Published: January 2023

IntroduzioneSe per «maestro» intendiamo qualcuno che mette insieme un ampio gruppo di subordinati e fa eseguire loro la musica di qualcun altro, Juan José Linz non è, e non è mai stato tale. È sempre stato un «compositore» — qualcuno che scrive e suona la propria musica. E, tuttavia, dato che ha spesso riunito un certo numero di collaboratori, e scritto e diretto musica insieme a loro, chiamiamolo il «maestro-compositore» della scienza politica.