bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of kharif rainfed rice yield predictability using Extended Range Forecast System over Madhya Pradesh, India
Authors: A MEHNAJ THARRANUM. , D.R. Pattanaik , Goroshi Sheshakumar 
Published: September 2023

Abstract

The estimation of rice yields using weather observations of three consecutive seasons: 2019, 2020 and 2021, and comparing them with spliced up extended range forecasts of every week from Southwest monsoon seasons JJAS-2019, 2020 and 2021, respectively, gives a glimpse into usability of ERF in future, for the purpose of agriculture. The performance assessment in effectively simulating rainfed rice yields has been done for over 10 districts of Madhya Pradesh, using crop simulation model DSSAT v.4.8, for the seasons 2019, 2020 and 2021, covering JJAS (June, July, August and September) monsoon season. The correlations carried between Yield, Harvest Index (HI) forecasts obtained using category 1 dataset (only observed weather) and category 2 (observed + ERF +Normal) and category 3 (observed + Normal) shows that replacing climatological normal with ERF at vegetative phase of the rainfed rice crop doesn’t show much improvement in its performance, except for season 2019 HI. In reproductive phase, only in 2021 season, yield and HI forecasts obtained with category 2 dataset with ERF splicing, were found to have better correlation coefficients with those obtained with category 1 dataset. Yield forecast obtained by splicing ERF data during October were better correlated to that obtained using observation weather, in ripening phase of the crop. It was also observed that only in 2021 season, stage 2 (End of Juvenile -Panicle Initiation phase) rainfall accumulation with ERF splicing was found to be better correlated with observed rainfall than that without ERF. Rainfall accumulated in Panicle Initiation -End of Leaf Growth phase (stage 3) achieved by splicing ERF data, was significantly correlated to observed rainfall than category 3 weather dataset rainfall without ERF, in season 2019. Rainfall accumulated in grain filling phase (stage 5) by splicing ERF data, was significantly correlated to observed rainfall only in season 2020 at date 14th October as initial (r= 0.922**), and was better than category 3 dataset whose correlation coefficient was 0.663* to observed rainfall.
Efficacy of MTwo-R Compared with M3-RT re-treatment files in Removing Obturation Material from Moderated Curved Root Canals: An ex-vivo Micro–Computed tomography study
Authors: Zhao-Wei TAI , Du Rong , Zhu Ya-Qin 
Published: September 2023

Abstract
Background: Comparing the advantages and drawsback of MTwo-R and M3-RT re-treatment files in root canal fillings removal in terms to provide references for clinical application.
Methods: After Twenty-eight mesial root canal with moderate curvature of extracted first mandibular permanent molar were collected, M3-PRO preparation files were used for root canal glide path and shaping preparation. All the samples were then underwent root canal obturation. MTwo-R and M3-RT re-treatment files were used to remove the root canal fillings. Micro-CT scan was used before and after the removal of root canal fillings. All data including time required and clearance rate of root canal fillings removal, apical transportation and deformation of re-treatment files were recorded. Independent sample t-test and chi-square testwere used to compare the differences between groups.
Results: M3-RT group exhibited a higher efficiency and clearance rate in root canal fillings removal; Apical transportation occurred at apical 1mm, 3mm and 5mm in both M3-RT and MTwo-R groups; MTwo-Rgroup exhibited a higher instruments deformation rate in re-treatment files.
Conclusion: M3-RT re-treatment files showed higher efficiency and clearance rate in root canal fillings removal, as well as the lifespan and safety coefficientwhen compared with MTwo-R system. Thus, M3-RT is more suitable for root canal fillings removal in moderate curved root canals when apical transportation rate is not significant.
Spatial Distribution of Drought Vulnerability Mapping: Introducing a new methodology
Authors: Li HeYu , Meng XiangJie , Arabameri Alireza , santosh M , Arora Aman 
Published: September 2023

Abstract
Droughts as a natural calamity have wreaked havoc on human health, environment, and the economy around the world. Due to its complex and multi-faceted nature, the risk assessment of drought requires the analysis of diverse parameters and machine learning techniques provide an effective tool to approach this problem. In the present work, we have employed four machine learning models, Naïve Bayes (NB), Rotational tree- Forest by Penalizing Attributes (RF-FPA), Multi-Layer Perceptron (MLP), and Linear Discriminant Analysis (LDA) for the drought vulnerability mapping in the Najafabad watershed, Isfahan Province, Iran. The country faces serious challenge from hydrological and meteorological drought conditions. A total of 20 conditioning factors comprising of 3 topographical (slope, elevation, geomorphology), 6 environmental (NDVI, soil depth, LU/LC, soil texture, EC, soil moisture), 4 hydrological (groundwater level, drainage density, distance to stream, TWI), 4 meteorological (annual precipitation and temperature, evaporation, humidity), and 3 socio-economic (ADP, deep tune, population density) were included for the drought vulnerability mapping. The collinearity effects were checked with multicollinearity analysis prior to the spatial modelling. The variable importance of the different parameters was analysed using AdaBoost model. The results show that soil moisture is the most important parameters among all variables. It also came into the results that the RF-FPA, among all four models, is the most successful model during training (AUC = 0.976) and validation (AUC = 0.968).
Short-term and long-term efficacy of accelerated transcranial magnetic stimulation for depression: A systematic review and meta-analysis
Authors: Shi Ruifeng , Wang Zuxin , Yang Dong , Hu Yujie , Zhang Zhongyang , Lan Daotao , Su Yihan , Wang Yunqiong 
Published: September 2023

Abstract
Background
In recent years, accelerated transcranial magnetic stimulation (aTMS) has been developed, which has a shortened treatment period. The aim of this study was to evaluate the efficacy and long-term maintenance effects of aTMS in patients with major depressive disorder (MDD).
Methods
We systematically searched online databases for aTMS studies in patients with MDD published before February 2023 and performed a meta-analysis on the extracted data.
Results
Four randomized controlled trials (RCTs) and 10 before-and-after controlled studies were included. The results showed that depression scores were significantly lower after the intervention than before (SMD = 1.80, 95% CI (1.31, 2.30), P < 0.00001). There was no significant difference in antidepressant efficacy between aTMS and standard TMS (SMD = -0.67, 95% CI (-1.62, 0.27), P = 0.16). The depression scores at follow-up were lower than those immediately after the intervention postexperimental based on the depression rating scale (SMD = 0.22, 95% CI (0.06, 0.37), P = 0.006). This suggests that there may be a long-term maintenance effect of aTMS. The results of the subgroup meta-analysis suggest that the delayed effect of aTMS may be related to the stimulation pattern of TMS, that there may be a delayed effect of the rTMS pattern in that depressive symptoms continue to remit after cessation of stimulation (SMD = 0.29, 95% CI (0.10, 0.49), I2 = 22%, p = 0.003) and that the iTBS pattern may only maintain the posttreatment outcome (SMD = 0.01, 95% CI (-0.45, 0.47), I2 = 66%, p = 0.98).
Conclusions
aTMS can rapidly improve depressive symptoms, with no significant drop in efficacy compared to standard TMS. aTMS may also have long-term maintenance effects, but longer follow-up periods are needed to evaluate this possibility.
Trial registration:
This article is original and not under simultaneous consideration by another publication. The study has been registered on PROSPERO (https://www.crd.york.ac.uk/prospero/) (Number: CRD42023406590)
δ98/95 Mo records in ferromanganese crust suggest downward movement of Oxygen Minimum Zones in the early Eocene
Authors: Li Jie , Yin Lu , Zhang Jing , Yao Huiqiang , Lin Zhiyong , Zhao Pei-Pei , Long Xiaoping , Xu Yigang 
Published: September 2023

Abstract

The seawater Molybdenum isotopic composition has been thought to have undergone little change over the Cenozoic Era, compared to other redox sensitive isotope systems, such as Carbon and Sulfur. However, newly reconstructed Cenozoic Era seawater δ98/95 Mo values, based on analysis of a hydrogenic ferromanganese (Fe-Mn) crust obtained from the Pacific Ocean, reveal a significant decrease in seawater δ98/95Mo values from 2.80% at 53 Ma to 2.34% at 36.7 Ma. By utilizing a steady-state mass balance model, we observed that the primary factor contributing to this decline was likely the shrinkage of oxygen minimum zones (OMZ) in shallow shelf environments. OMZ sediments on shallow shelves typically exhibit lighter Mo isotope signatures than those on deep slopes and reduced burial of lighter Mo isotopes would reduce the seawater δ98/95Mo value. Coincidentally, this decline temporally coincided with the initial arc collision and subsequent closure of the foreland basin between India and Asia. Therefore, we consider that the seawater δ98/95 Mo may reflect the gradual contraction of the shallow shelf and downward migration of sediment along the continental margin in the early Eocene.
The influence of systemic condition and medications on alveolar bone loss and tooth attrition
Authors: Tagger-Green‬‎ Nirit , Refael Asaf , Szmukler-Moncler Serge , Nemcovsky Carlos , Chaushu Liat , Kolerman Roni 
Published: September 2023

Abstract
Background
Periodontitis is an infectious disease leading to reduced periodontal support, reflected radiographically as marginal bone loss (MBL). Periodontitis is linked to systemic conditions like cardiovascular disease, diabetes, arthritis, etc. Periodontitis elevates the bacterial load and spreads systemic inflammation through infection and inflammation. Risk factors, including medications, smoking, age, and gender, can influence periodontal health. Tooth wear, characterized by irreversible enamel and dentin changes like wear facets, cracks, or fractures, has limited documented systemic conditions and medication associations.
Aim
To assess the influence of systemic conditions and medication on radiographic signs of tooth wear (TW) and marginal bone loss (MBL).
Materials and methods
A retrospective analysis encompassed 3900 patients with detailed medical documentation, including systemic diseases and medication, and a full-mouth radiographic survey. Odds ratio and logistic regression analysis were applied to ascertain the correlation between systemic conditions and medication on MBL and TW.
Results
Most systemic conditions exhibited a significant effect on TW and/or MBL. Age, gender, and smoking exhibited an elevated odds ratio for TW occurrence. Age, gender, smoking, diabetes, and psychiatric conditions were associated with an increased odds ratio for MBL.
Conclusion
Most systemic conditions and medications notably impacted MBL, with TW showing a less pronounced impact.
The lightening Secret of Halosydnella punctulata (Grube, 1856)
Authors: Miranda Vinicius Rocha , Brasil Ana Claudia dos Santos 
Published: September 2023

Abstract
Animals use two pathways to emit light: bioluminescence and fluorescence. Bioluminescence occurs through chemical reactions, while fluorescence is a physical response where light energy is absorbed and reflected in a different spectrum. Bioluminescence has been reported in several polychaete species, especially in Polynoidae, while fluorescence is relatively unknown. Halosydnella, a genus of Polynoidae, has six valid species occurring in South and Central America, and none of them were known to produce light. Here we report the occurrence of fluorescence in the elytra of the anterior region of H. punctulata that can be observed in living specimens illuminated with Ultra Violet light, as well as in preserved specimens.
A New Method to Evaluate Lower Esophageal Distension Capacity in Eosinophilic Esophagitis by using functional lumen imaging probe (Endoflip™)
Authors: Casabona-Francés Sergio , Sanz-García Ancor , Ortega Guillermo , Santander Cecilio , Perez-Fernandez Teresa , Majano Pedro , Olalla José María , Juárez-Tosina Rocío , Mueller Ralph , Attwood Stephen , Lucendo Alfredo 
Published: September 2023

Abstract
Background
Endoluminal functional lumen impedance planimetry (EndoflipTM) has become the gold standard to evaluate esophageal distensibility, although the study itself and its analysis present challenges. We propose here a new method to assess lower esophageal distension capacity, which overcomes several limitations of prior approaches including incomplete and corrupted EndoflipTM recordings.
Methods
Esophageal distension capacity was evaluated with a 16-channel EndoflipTM in 10 controls and 14 patients with Eosinophilic Esophagitis (EoE). Controls were evaluated once. EoE patients were evaluated at baseline and after at least six weeks treatment with budesonide orodispersible tablet 1mg bd.
Balloon volumes were increased 5-mL stepwise either reaching maximum volume of 60 mL, or maximum balloon pressure of 60mmHg. Recordings were analyzed with a home-made R script. The mean esophageal diameter at 60 mL D(60mL) was calculated or extrapolated depending on whether the 60 mL volume was reached.
Results
By fitting a Michaelis-Menten curve across all measured diameters throughout all constant volume steps, mean D(60mL) was estimated. For control subjects, the mean±SD value of diameter at D(60mL) was 17.08±1.69 mm and for EoE patients at baseline D(60mL) was 14.51±2.68 mm. After six weeks of treatment of EoE patients, D(60mL) significantly increased to 16.22±1.86mm (paired Wilcoxon signed test: p=0.0052), although the values for control subjects were not reached.
Conclusions
Estimated mean esophageal diameter at 60 mL is a good proxy for esophageal distension capacity, which correlates with clinical outcomes in EoE. The method presented in this study overcome difficulties encountered during the standard measurement protocol, allowing analysis of recordings from incomplete and corrupted registries.
Pan-cancer Analysis of the Prognostic and Immunological Effects of PIK3C3
Authors: Xie Qianxin , Zhou Jie , Guan Junfeng , She Siqi , Li Junfeng , Liu Wenhong , Xu Ye , Hu Mengjiao , Tao Fangfang 
Published: September 2023

Abstract
Background
Autophagy-related protein plays a pivotal role in cancer development, progression, and prognosis. Among these proteins, PIK3C3 holds significant importance as it is involved in canonical autophagy, endocytosis, and vesicle trafficking, thereby exerting influential effects on various types of cancer progression. However, the diverse biological significance of PIK3C3 in pan-cancer has not been systematically and comprehensively studied.
Methods: Data from The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) were utilized, and bioinformatics approaches were also employed to explore the potential mechanisms of PIK3C3 in diverse cancers.
Results: PIK3C3 exhibited upregulation in several tumors and showed prognostic associations. Low expression of PIK3C3 predicted poorer overall survival (OS) in kidney renal clear cell carcinoma patients, while high expression of PIK3C3 predicted poorer OS in adrenocortical carcinoma, bladder urothelial carcinoma, brain lower grade glioma, and liver hepatocellular carcinoma. Additionally, PIK3C3 expression significantly correlated with immune infiltrating cells and tumor mutational burden, microsatellite instability and neoantigens in several cancer types. Furthermore, knockdown of PIK3C3 in colorectal cancer cells lines significantly suppressed cell proliferation and metastasis.
Conclusion: PIK3C3 can be used as an auxiliary indicator for early tumor diagnosis and a prognostic marker for many types of tumors.
ARDS patients with CRS less than 45 cm/H2O and small body sizes may not be fit for high-PEEP levels: A secondary analysis of a randomized controlled trial
Authors: Zhang Ximu , Cao Chongfeng , Ma LeWei , Zhang Shi 
Published: September 2023

Abstract
Object: Identification of respiratory mechanics phenotypes could provide novel information for the selection of suitable positive end-expiratory pressure (PEEP) in specific ARDS patients.
Methods: Patient information data and other data in the current study were downloaded from a randomized controlled trial (low-PEEP vs. high-PEEP for ARDS) on the ARDS network public database (http://www.ardsnet.org/). Based on respiratory mechanics characteristics, phenotypes were identified through an unsupervised clustering algorithm applied to routinely available respiratory mechanics features within 24 hours of hospital presentation before the patients were treated with lower-PEEP or higher-PEEP. The respiratory mechanics characteristics included direct or indirect lung injury, respiratory rate, mean airway pressure, inhaled oxygen concentration, arterial partial pressure of oxygen, arterial partial pressure of carbon dioxide, respiratory system compliance (CRS) and plateau pressure. Statistical analysis of 60-day mortality was utilized to identify specific patients with ARDS who could benefit (or could be harmed) from a lower versus a higher PEEP, with a P<0.05 cut-off.
Results: A total of 549 patients with ARDS were enrolled in the current secondary analysis, of which 273 patients had a low-PEEP (8.3±3.2 cm/H2O), and 276 patients had a high-PEEP (13.2±3.5 cm/H2O). Three respiratory mechanics phenotypes were identified, and phenotype I was classified as the “higher-PEEP not fit for” phenotype since higher-PEEP resulted in a significant increase in 60-day mortality compared with low-PEEP (39.0% vs 23.1%). Patients with phenotype I showed a worse CRS (29.8±16.1 ml/cm/H2O), were more commonly female (67.3%) and were more commonly characterised by a lower height (164.5±7.5 cm) and/or a decreased weight (76.8±20.3 kg). Statistical analysis of the mortality indicated that there were no significant differences between the high-PEEP groups and low-PEEP groups in the cohorts with other phenotypes.
Conclusion: ARDS patients with CRS less than 45 cm/H2O and a small body size may not be good candidates for a high-PEEP strategy.
Effect of mental illness stigma upon the quality of life among families with schizophrenic patients in Mental Health Centre, Sulaimaniyah, Iraq
Authors: Abdulkarim Araz Mohammed 
Published: September 2023

AbstractBackground:Family caregivers of members with schizophrenia are subjected to stigmatization that significantly affects the quality of life (QoL) and causes delays in caregiving and treatment seeking for schizophrenic patients.Objective:To assess the stigma of mental illness and QoL levels and to determine its association among family caregivers of schizophrenic patients.Patients and Methods:A quantitative cross-sectional study was performed on 100 family caregivers with schizophrenia in 100 patients selected at the Mental Health Center, General Teaching Hospital in Sulaimaniyah, Iraq, from December 2022 to February 2023. A questionnaire used for data collection by interviewing the caregivers was composed of three parts; socio-demographic characteristics of family caregivers and patients, the stigma of mental illness scale, and QoL-BREF.Results:Most family caregivers of patients with schizophrenia were males (72%) and siblings (49%). Moderate prevalence of stigma (78%) and low level of life (91%) levels were observed among caregivers. The likelihood ratio test results indicated that stigma was significantly associated with QoL (LR=4.912, P<0.05). The multinomial logistic regression model analysis showed that family caregivers with a high level of stigma were significantly four times lower QoL (P<0.05, odds ratio=4.43).Conclusions:Family caregivers experienced a moderate level of stigma and low QoL that reflects a failure to use practical approaches to prompt and satisfy their needs in the community.
Low mercury concentrations in a Greenland glacial fjord attributed to oceanic sources
Authors: Lindeman Margaret , Straneo Fiammetta , Adams Hannah , Nelson Monica , Schartup Amina 
Published: September 2023

Abstract

High mercury concentrations found in meltwater from the southwest Greenland Ice Sheet and surface waters of nearby fjords, including neurotoxic and bioaccumulative methylmercury (MeHg), have raised concerns about regional ecosystem and community health. We present full water column profiles of MeHg and total mercury (THg) from Sermilik Fjord, a large glacial fjord in southeast Greenland, fed by multiple marine-terminating glaciers. We measured THg concentrations of 0.23-1.1 pM and MeHg of 0.02-0.17 pM, similar to nearby coastal waters and 1-3 orders of magnitude lower than reported in southwest Greenland. We show that the dominant source of mercury species to the fjord is inflowing ocean waters from the continental shelf, while the exported glacially-modified waters are relatively depleted in inorganic mercury (Hg(II)). We deduce that Hg(II) is removed from the water column within the fjord, implying that the fjord is a net sink of oceanic mercury.
Physical activity and sleep changes among children with obesity during a period of school closures related to the COVID-19 pandemic
Authors: Dunn Jessilyn , Singh Karnika , Armstrong Sarah , Wagner Brooke , Counts Julie , Skinner Asheley , Kay Melissa , Li Jennifer , Shah Svati , Zucker Nancy , Neshteruk Cody , Suarez Lilianna , Kraus William , Zizzi Alexandra 
Published: September 2023

Abstract
Daily routines, including in-person school and extracurricular activities, are important for maintaining healthy physical activity and sleep habits in children. The COVID-19 pandemic significantly disrupted daily routines as in-person school and activities closed to prevent spread of SARS-CoV-2. We aimed to examine and assess differences in objectively measured physical activity levels and sleep patterns from wearable sensors in children with obesity before, during, and after a period of school and extracurricular activity closures associated with the COVID-19 pandemic. We compared average step count and sleep patterns (using the Mann Whitney U Test) before and during the pandemic-associated school closures by using data from activity tracker wristbands (Garmin VivoFit 3). Data was collected from 94 children (aged 5-17) with obesity, who were enrolled in a randomized controlled trial testing a community-based lifestyle intervention for a duration of 12-months. During the period that in-person school and extracurricular activities were closed due to the COVID-19 pandemic, children with obesity experienced objectively-measured decreases in physical activity, and sleep duration. From March 15, 2020 to March 31, 2021, corresponding with local school closures, average daily step count decreased by 1,655 steps. Sleep onset and wake time were delayed by about an hour and 45 minutes, respectively, while sleep duration decreased by over 12 minutes as compared with the pre-closure period. Step counts increased with the resumption of in-person activities. These findings provide objective evidence for parents, clinicians, and public health professionals on the importance of in-person daily activities and routines on health behaviors, particularly for children with pre-existing obesity. We demonstrate the utility of wearable sensors in objectively measuring longitudinal physical activity and sleep behavior patterns in children with obesity and in quantifying changes in their health behaviors due to disruption of structured, daily routines following in-person school closures during the COVID-19 pandemic.
Trial Registration: Clinical trial registration: NCT03339440.