bluuebunny/crossref_metadata_2025_split huggingface dataset:
Can SARS‐CoV‐2 screening in oral biopsies aid epidemiological surveillance?
Authors: Martins‐Chaves Roberta Rayra , Diniz Marina Gonçalves , Miguita Lucyene , Felix Fernanda Aragão , Rocha Fernanda Faria , Fonseca Paula Luize Camargos , Geddes Victor Emmanuel Viana , Menezes Diego , Moreira Rennan Garcias , Liborio‐Kimura Tatiana , Câmara Jeconias , da Costa Mendes Tássia Caroline , Pontes Hélder Antônio Rebelo , Pontes Flavia Sirotheau Correa , de Freitas Gonçalves Thayanne Oliveira , Fonsêca Thamyres Campos , Abrahão Aline Corrêa , Romañach Mário José , Alves Ana Paula Negreiros Nunes , Pereira Karuza Maria Alves , da Cruz Perez Danyel Elias , de Amorim Carvalho Elaine Judite , dos Santos Jean Nunes , de Aquino Xavier Flávia Caló , Giffoni Fernando Costa , de Souza Alessandra Hubner , Gomes Carolina Cavaliéri , de Sousa Sílvia Ferreira , Fonseca Felipe Paiva , de Souza Renan Pedra , Aguiar Renato Santana , Gomez Ricardo Santiago 
Published: May 2023

AbstractBackgroundThree years after the first confirmed COVID‐19 case in Brazil, the outcomes of Federal government omissions in managing the crisis and anti‐science stance heading into the pandemic have become even more evident. With over 36 million confirmed cases and nearly 700 000 deaths up to January 2023, the country is one of the hardest‐hit places in the world. The lack of mass‐testing programs was a critical broken pillar responsible for the quick and uncontrolled SARS‐CoV‐2 spread throughout the Brazilian population. Faced with this situation, we aimed to perform the routine SARS‐CoV‐2 screening through RT‐qPCR of oral biopsies samples to aid in the asymptomatic epidemiological surveillance during the principal outbreak periods.MethodsWe analyzed 649 formalin‐fixed paraffin‐embedded oral tissue samples from five important oral and maxillofacial pathology laboratories from the north, northeast, and southeast geographic regions of Brazil. We also sequenced the whole viral genome of positive cases to investigate SARS‐CoV‐2 variants.ResultsThe virus was detected in 9/649 analyzed samples, of which three harbored the Variant of Concern Alpha (B.1.1.7).ConclusionAlthough our approach did not value aiding asymptomatic epidemiological surveillance, we could successfully identify a using FFPE tissue samples. Therefore, we suggest using FFPE tissue samples from patients who have confirmed diagnosis of SARS‐CoV‐2 infection for phylogenetic reconstruction and contraindicate the routine laboratory screening of these samples as a tool for asymptomatic epidemiological surveillance.
Effect of abiotic factors on progress and severity of sheath rot (Sarocladium oryzae) in rice
Authors: Mehta Amritpal , Singh S. K. , Wani Owais Ali , Ahanger Shafat Ahmad , Basu Umer , Vaid Amrish , Sharma Sonali , Basandrai Ashwani Kumar 
Published: May 2023

AbstractSheath rot, caused by Sarocladium oryzae, is an emerging serious threat in rice cultivating regions especially in Union Territory of Jammu & Kashmir, causing yield losses of 20%–85%. Little and scattered information is available on the epidemiology of the disease. Hence, the field experiments were conducted during the cropping seasons of 2019 and 2020 to find out the effect of weather factors on the development of the disease as well as computation of predictive model for its initiation and spread in the field in five popular and commercially grown rice varieties viz. PB‐1509, PB‐1401, PR‐114, PB‐1121 and Arize 6444 Gold. The higher mean percent disease index (PDI) of 37.3% was recorded during 2019, whereas it was 33.8% during 2020. The effect of cropping seasons (years) on PDI, area under disease progress curve (AUDPC) and infection rate (r) was significant. Significant and negative correlation was observed between PDI and selected meteorological parameters, that is maximum and minimum temperature and relative humidity in the evening during both the cropping seasons The PDI had positive and significant correlation with relative humidity in the morning during the cropping season 2020. Rainfall showed significant and negative correlation with PDI in all the varieties during 2019 whereas it was non‐ significant and positive during 2020 in all the varieties except PR‐114 where, it was positive and significantly correlated. Minimum temperature, morning and evening relative humidity and sunshine hours resulted in ~92%–95% and 97%–99% variation for PDI in all the varieties during the cropping seasons 2019 and 2020, respectively. Sheath rot was the maximum recorded at minimum temperature (11.5–20.0°C), high morning relative humidity (74.0%–94.0%) and moderate evening relative humidity (26.0%–75.0%) and sunshine hours of 2.8–9.3 h, respectively. All the assumptions related to the developed model were acceptable as the global stat, skewness, kurtosis, link function and heteroscedasticity tests had the least p‐values in all the varieties during both the cropping seasons. Hence the model may be used for the prediction of sheath rot, which would be helpful in the early adoption, precise and judicious management practices.
Serum insulin concentration in dogs with insulinoma as a clinical marker for presence of metastasis at the time of diagnosis
Authors: Petrelli Andrea , German Alexander J. , O'Connell Erin M. , Silvestrini Paolo 
Published: May 2023

AbstractBackgroundInformation regarding serum insulin concentration in dogs newly diagnosed with insulinoma and its association with clinical stage and survival time is lacking.ObjectiveExamine association between serum insulin concentration and survival and clinical disease stage in dogs with insulinoma.Animals.Fifty‐nine client‐owned dogs with a diagnosis of insulinoma from 2 referral hospitals.MethodRetrospective observational study. The χ2 test was used to compare the proportion of dogs with increased insulin concentration in groups with or without metastasis at the time of diagnosis. Linear mixed‐effect models were built to compare differences in insulin concentration between dogs with and without evidence of metastasis at the time of original diagnosis. Cox's proportional hazards regression and Kaplan‐Meier graphs were used to evaluate the association between insulin concentration and insulin groups and survival.ResultsMedian serum insulin concentration was 33 mIU/L (range, 8‐200 mIU/L) in dogs with World Health Organization (WHO) stage I disease and 45 mIU/L (range, 12‐213 mIU/L) in dogs with WHO stage II and III disease. No difference was found in the proportion of dogs with increased insulin concentration with or without metastasis (P = .09). No association was identified between insulin concentration and survival (P = .63), and between dogs grouped by insulin concentration and survival (P = .51).Conclusions and Clinical ImportanceSerum insulin concentrations were not different between dogs with or without metastasis at diagnosis. The degree of insulinemia does not provide further information regarding the stage of the disease and is not associated with survival time in dogs with insulinoma.
The macroeconomic effects of endogenous credit and money creation under Basel III regulations
Authors: Li Boyao 
Published: May 2023

AbstractBank regulations affect the behaviour of credit and money creation; hence, they are essential for economic growth and stability. This paper develops an analytical model of the monetary circuit to show the macroeconomic effects of money creation under bank regulations. It describes the equilibrium in which banks create money in accordance with capital adequacy ratios or net stable funding ratios. This study reveals the equilibrium economic growth rate and debt level. In addition, this paper demonstrates how bank regulations influence firm capital structures, and the conditions for firms using debt and filing for bankruptcy. Results show that bank regulations can transfer risk from banks to firms. In fact, this study identifies a channel through which banks actively influence the macroeconomy through their money creation.
From grasses to succulents – development and function of distinct stomatal subsidiary cells
Authors: Cheng Xin , Raissig Michael T. 
Published: May 2023

SummaryStomata are breathing pores on leaves that balance photosynthetic carbon dioxide uptake and water vapor loss. Stomatal morphology and complexity are rather diverse when considering stomatal subsidiary cells (SCs). Subsidiary cells are adjacent to the central guard cells (GCs) and are morphologically distinct from other epidermal cells. Yet, how various SCs develop and whether and how they support stomatal gas exchange physiology outside of the grass family is largely unknown. Here, we discuss the development, ontogeny, and putative function of paracytic vs anisocytic SCs, which can be found in grasses and Crassulaceae succulents, respectively. First, we highlight recent advances in understanding how grasses form stomatal SCs. We then summarize novel insights into stomatal development in SC‐less Arabidopsis to speculate on how this stomatal program might be rewired to enable anisocytic SC formation. Finally, we discuss the functional relevance of paracytic SCs in grasses and the putative roles of anisocytic SCs in succulents.
Fertility Intentions During the Covid‐19 Pandemic: An Analysis of Individual‐ and Municipality‐Level Determinants
Authors: Marteleto Letícia J. , Kumar Sneha , Dondero Molly , Gustavo Fernandes Sereno Luiz 
Published: May 2023

AbstractRecognizing the prolonged, uneven, and evolving nature of the Covid‐19 pandemic, this study provides one of the first dynamic, multilevel perspectives of women's fertility intentions in response to the pandemic and its multifaceted impacts. We examine how evolving individual‐ and community‐level Covid‐19 risk mechanisms and socioeconomic and life‐course conditions are associated with continuity and change in women's fertility intentions. We combine individual‐level panel data from a population‐based sample of women aged 18–34 in Pernambuco, Brazil in 2020 and 2021 with corresponding administrative data from 94 municipalities. We use multinomial logit regressions to model continuity and change in fertility intentions across waves. We then estimate fixed effect models to highlight the time‐varying determinants of changing fertility intentions while accounting for unobserved, time‐invariant individual factors. We find that high and/or increasing individual and community‐level Covid‐19 exposure is associated with a greater likelihood of abandoning initial childbearing plans and a greater likelihood to maintain intentions to forego versus to intend having additional children. We advance the literature by highlighting how individual‐level Covid‐19 infection risk perceptions matter for fertility intentions, net of community‐level exposure, and the necessity of dynamic perspectives for understanding how fertility intentions have changed (or not) in response to the pandemic.
Identification of quantitative trait loci and candidate genes controlling the tocopherol synthesis pathway in soybean (Glycine max)
Authors: Park Cheolwoo , Liu Dequan , Wang Qingyu , Xu Donghe 
Published: May 2023

AbstractA recombinant inbred line (RIL) population was used to identify quantitative trait loci (QTLs) and their candidate genes controlling the tocopherol (Toc) synthesis pathway. The RIL population was cultivated in field conditions in 3 years. A genetic map constructed using 1624 DNA markers was used for QTL analysis. We identified 22 QTLs for seed tocopherol contents and their ratios, of which two QTL clusters on chromosomes (Chr) 9 and 14 exerted consistent large effects on tocopherol composition across the 3 years. The QTL cluster localized on Chr 9 might correspond to γ‐TMT3, which controls the conversion of γ‐Toc into α‐Toc. The QTL cluster localized on Chr 14 was novel, which might regulate the conversion of MPBQ (a precursor of δ‐Toc) into DMPBQ (the precursor of γ‐Toc). The effect of the QTL cluster on Chr 14 was validated in a pair of near isogenic lines, and its candidate gene was mined. The identified QTLs and their candidate genes might be used in breeding programmes to improve α‐Toc content in soybean seeds.
What analytic metaphysics can do for scientific metaphysics
Authors: Lee Chanwoo 
Published: May 2023

AbstractThe apparent chasm between two camps in metaphysics, analytic metaphysics and scientific metaphysics, is well recognized. I argue that the relationship between them is not necessarily a rivalry; a division of labour that resembles the relationship between pure mathematics and science is possible. As a case study, I look into the metaphysical underdetermination argument for ontic structural realism, a well‐known position in scientific metaphysics, together with an argument for the position in analytic metaphysics known as ontological nihilism. I argue that we can ascribe the same schema to both arguments, which indicates that analytic metaphysics can offer an abstract model that scientific metaphysics may find useful.
Safety first, but for whom? Shifts in risk perception for self and others following COVID‐19 vaccination
Authors: Choi Soyeon , Merrell Wilson N. , Ackerman Joshua M. 
Published: May 2023

AbstractVaccines can affect the mind as well as the body. Research on the psychological impact of vaccines has largely focused on risk‐related judgments and behaviors involving the recipient. Here, we extend this work to risk‐related judgments of others. In a prospective cohort study involving three samples and two timepoints (N = 588 adults), we tested competing hypotheses about the effects of receiving a COVID‐19 vaccine on perceived risks to the unvaccinated: (1) a self/other differentiation hypothesis (vaccination will lead to estimation of lower risk for the self but higher risk for others) versus (2) a self/other correspondence hypothesis (vaccination will lead to estimation of lower risk from contracting COVID‐19 for both self and others). Results revealed risk estimates as well as preferences for COVID‐related social policies more consistent with the former hypothesis. We discuss potential psychological mechanisms and implications of these findings.
Laser‐assisted blepharoplasty: An innovative safe and effective technique
Authors: Bonan Paolo , Fusco Irene , Bruscino Nicola , Madeddu Francesca , Troiano Michela , Verdelli Alice , Piccolo Domenico , Rampino Giuseppe 
Published: May 2023

AbstractBackgroundBlepharoplasty is one of the most popular esthetic procedures with an acceptable risk profile and a relatively quick procedure.MethodsThe aim was to evaluate the efficacy and safety of a new CO2 and 1540‐nm laser‐assisted blepharoplasty technique applied to the upper and lower eyelids. A total of 38 patients were enrolled. Photographs were taken before the treatment and at 6‐month follow‐up. One “blind” observer assessed the performance of this technique by ranking the results in four categories of eyelid esthetic: 1 = no or poor results (0%–25%), 2 = slight improvement (25%–50%), 3 = moderate improvement (50%–75%) and 4 = marked improvement (75%–100%). All possible complications were monitored.ResultsThirty‐two patients (84 %) achieved marked improvement, four patients (11%) moderate improvement, two patients (5 %) slight improvement, while zero subjects (0%) poor or no improvement. No serious adverse effects were observed.ConclusionsOur results from clinical evaluations suggest that the CO2 and 1540‐nm laser assisted blepharoplasty is proved to be a sophisticate intervention efficacious in improving the treatment of patients with various degrees of eyelid and periocular aging and also in reducing downtime.
Identifying Suitable Three-Dimensional Bio-Printed Scaffold Architectures to Incubate in a Perfusion Bioreactor: Simulation and Experimental Approaches
Authors: Mankowsky Jack , Quigley Connor , Clark Scott , Habib Ahasan 
Published: May 2023

Abstract
Traditional cell culturing methods are limited in their ability to supply growth medium to cells within scaffolds. To address this, we developed a custom perfusion bioreactor that allows for dynamic medium supply to encapsulated or seeded cells. Our custom-designed bioreactor improves the in vivo stimuli and conditions, which may enhance cell viability and proliferation performance. Some of the efforts include using dual medium tanks to replace the medium without stopping perfusion and a newly designed perfusion chamber that can accommodate an array of cassettes allowing for a wide assortment of scaffold shapes and sizes. In this paper, we explored the response of fluid flow to certain types of scaffold pore geometries and porosities using simulation and experimental approaches. Various pore geometries were considered, such as uniform triangular, square, diamond, circular, and honeycomb having uniform and variable sizes. Finally, bone tissue architecture was mimicked and simulated to identify the impact of fluid flow. Based on the results, optimum pore geometry for scaffolds were determined. We explored real-time fluid flow response on scaffolds fabricated with 8% Alginate, 4% Alginate-4% Carboxymethyl Cellulose (CMC), and 2% Alginate-6% CMC incubated, allowing a constant fluid flow for various periods such as 1, 2, 4, and 8 h. The change of fabricated scaffolds was determined in terms of swelling rate, i.e., change of filament width and material diffusion, i.e., comparison of dry material weight before and after incubation. This comparative study can assist in application-based materials selection suitable for incubating in a perfusion bioreactor.
Crack Identification by Digital Image Correlation Method Using Crack Shape as Prior Information
Authors: Hana Norihiko , Umeda Masaki , Akiyoshi Masao , Mitamura Kazushi , Amaya Kenji 
Published: May 2023

Abstract
A new crack identification method that estimates the cracks in invisible locations based on the surface deformation measured by digital image correlation (DIC) is developed. An inverse problem is setup to estimate such invisible cracks from surface deformations. The inverse problem has an ill-condition because of noise contained in surface deformations. Our proposed regularization method uses prior information and Expectation a Posteriori (EAP) estimation. Prior information includes candidate crack shapes and surface deformations due to cracks. The candidate crack shapes are created by determining a crack's starting point and propagating it based on the force at its perimeter (ligament). A prior distribution is the surface deformations due to the candidate crack shapes. The likelihood distribution is a surface deformation measured by the DIC method. A posterior distribution is defined from the prior and likelihood distributions. In this study, the estimated result is the expected value of the posterior distribution. The validation test was performed, and the result shows that the proposed method superior to the conventional L1-norm regularization method.
Effects of MFI Zeolite Crystal Size on Light Olefins Production in Catalytic Cracking of Hydrocarbon Feedstocks
Authors: Bachurina D. O. , Yurtaeva A. S. , Koveza V. A. , Potapenko O. V. , Ivanova I. I. 
Published: May 2023

Abstract
The paper describes the physicochemical characterization and catalytic testing of MFI zeolites with crystal sizes ranging from 0.15 to 6 μm supplied by different manufacturers. The physicochemical properties were examined by atomic absorption spectrometry, X-ray fluorescence analysis, scanning electron microscopy, low-temperature nitrogen adsorption, and ammonia temperature-programmed desorption. The MFI zeolites were then added to a cracking catalyst and subjected to catalytic testing in the conversion of cyclohexane and hydrotreated vacuum gas oil (HTVGO). It was found that the conversion of the model cyclohexane feedstock was significantly enhanced when the crystal size of the MFI zeolite added to the cracking catalyst was reduced from the micro- to submicro-scale; on the other hand, an equal downsizing had almost no effect on the conversion of the real HTVGO feed. However, the use of submicrosized MFI crystals in HTVGO cracking decreased the contribution of hydrogen transfer reactions, thus reducing coke deposits.
GAIA Arguments for and against a Hypothetical Sun Companion
Authors: Malkov O. Yu. 
Published: May 2023

Abstract
The hypothesis that the Sun is a component of a binary star system has been around for about a hundred years. Assumptions about the nature of the companion continue to be published as new observational data become available. The paper shows that the results of the work of the Gaia space observatory impose certain restrictions on the nature and location of the companion. The fact that the companion is not registered by the observatory leaves the following marginal possibilities: a cool brown dwarf (Y3 and later) in an orbit inside the Oort cloud, or an L/T brown dwarf in a higher orbit (from $$a \approx $$ 105 AU). At the same time, the companion is quite likely cataloged in the 2MASS and WISE surveys. We also provided estimates for the absolute G-magnitudes of brown dwarfs of late spectral types.
Vitamin D testing in children and adolescents in Victoria, Australia: are testing practices in line with global recommendations?
Authors: Zurynski Yvonne , Munns Craig Frank , Sezgin Gorkem , Imai Chisato , Georgiou Andrew 
Published: May 2023

ObjectiveTo describe changing primary care ordering of serum 25-hydroxyvitamin D (25OHD) tests in Australian children.DesignLongitudinal, population-based descriptive study of 25OHD testing using a large administrative dataset of pathology orders and results, 2003–2018.Setting and participantsThree primary health networks in Victoria, Australia. Patients aged ≤18 years with a serum 25OHD test ordered by the general practitioner (GP).Main outcome measuresTrends over 15 years in the number of 25OHD tests ordered, proportion indicating low levels or vitamin D deficiency and details of repeat testing.ResultsOf 970 816 laboratory tests, 61 809 (6.4%) included an order for a 25OHD test. The 61 809 tests were performed in 46 960 children or adolescents. The odds of ordering a 25OHD test in 2018 was 30.4 times higher compared with 2003 (95%CI 22.6 to 40.8, p<0.001). The odds of detecting a low 25OHD (<50 nmol/L) compared with the baseline in 2003 remained steady (adjusted OR<1.5) over time. Repeat tests (14 849) were undertaken in 9626 patients (median intertest interval 357 days, IQR 172–669 days). A total of 4603 test results indicated vitamin D deficiency (<30 nmol/L), but in only 180 (3.9%) of these was a repeat test performed within 3 months as recommended.ConclusionTesting volumes increased 30-fold, but the odds of detecting low 25OHD remained steady. Current Australian policy and the Global Consensus Recommendations for the prevention and management of nutritional rickets do not support routine 25OHD testing. Education and electronic pathology ordering tools may assist GPs to better align practice with current recommendations.