bluuebunny/crossref_metadata_2025_split huggingface dataset:
Revealing Surfactant Effect of Trifluoromethylbenzene in Medium‐Concentrated PC Electrolyte for Advanced Lithium‐Ion Batteries
Authors: Qin Mingsheng , Zeng Ziqi , Liu Xiaowei , Wu Yuanke , He Renjie , Zhong Wei , Cheng Shijie , Xie Jia 
Published: February 2023

AbstractDespite wide‐temperature tolerance and high‐voltage compatibility, employing propylene carbonate (PC) as electrolyte in lithium‐ion batteries (LIBs) is hampered by solvent co‐intercalation and graphite exfoliation due to incompetent solvent‐derived solid electrolyte interphase (SEI). Herein, trifluoromethylbenzene (PhCF3), featuring both specific adsorption and anion attraction, is utilized to regulate the interfacial behaviors and construct anion‐induced SEI at low Li salts’ concentration (<1 m). The adsorbed PhCF3, showing surfactant effect on graphite surface, induces preferential accumulation and facilitated decomposition of bis(fluorosulfonyl)imide anions (FSI−) based on the adsorption–attraction–reduction mechanism. As a result, PhCF3 successfully ameliorates graphite exfoliation‐induced cell failure in PC‐based electrolyte and enables the practical operation of NCM613/graphite pouch cell with high reversibility at 4.35 V (96% capacity retention over 300 cycles at 0.5 C). This work constructs stable anion‐derived SEI at low concentration of Li salt by regulating anions–co‐solvents interaction and electrode/electrolyte interfacial chemistries.
An “AND” Molecular Logic Gate as a Super‐Enhancers for De Novo Designing Activatable Probe and Its Application in Atherosclerosis Imaging
Authors: Sang Mangmang , Huang Yibo , Wang Lu , Chen Lei , Nawsherwan  , Li Gang , Wang Yan , Yu Xiu , Dai Cuilian , Zheng Jinrong 
Published: February 2023

AbstractDeveloping activatable fluorescent probes with superlative fluorescence enhancement factor (F/F0) to improve the signal‐to‐noise (S/N) ratio is still an urgent issue. “AND” molecular logic gates are emerging as a useful tool for enhanced probes selectivity and accuracy. Here, an “AND” logic gate is developed as super‐enhancers for designing activatable probes with huge F/F0 and S/N ratio. It utilizes lipid‐droplets (LDs) as controllable background input and sets the target analyte as variable input. The fluorescence is tremendously quenching due to double locking, thus an extreme F/F0 ratio of target analyte is obtained. Importantly, this probe can transfer to LDs after a response occurs. The target analyte can be directly visualized through the spatial location without a control group. Accordingly, a peroxynitrite (ONOO−) activatable probe (CNP2‐B) is de novo designed. The F/F0 of CNP2‐B achieves 2600 after reacting with ONOO−. Furthermore, CNP2‐B can transfer from mitochondria to lipid droplets after being activated. The higher selectivity and S/N ratio of CNP2‐B are obtained than commercial probe 3'‐(p‐hydroxyphenyl) fluorescein (HPFin vitro and in vivo. Therefore, the atherosclerotic plaques at mouse models are delineated clearly after administration with in situ CNP2‐B probe gel. Such input controllable “AND” logic gate is envisioned to execute more imaging tasks.
Brain‐Penetrating and Disease Site‐Targeting Manganese Dioxide‐Polymer‐Lipid Hybrid Nanoparticles Remodel Microenvironment of Alzheimer's Disease by Regulating Multiple Pathological Pathways
Authors: Park Elliya , Li Lily Yi , He Chunsheng , Abbasi Azhar Z. , Ahmed Taksim , Foltz Warren D. , O'Flaherty Regan , Zain Maham , Bonin Robert P. , Rauth Andrew M. , Fraser Paul E. , Henderson Jeffrey T. , Wu Xiao Yu 
Published: February 2023

AbstractFinding effective disease‐modifying treatment for Alzheimer's disease remains challenging due to an array of factors contributing to the loss of neural function. The current study demonstrates a new strategy, using multitargeted bioactive nanoparticles to modify the brain microenvironment to achieve therapeutic benefits in a well‐characterized mouse model of Alzheimer's disease. The application of brain‐penetrating manganese dioxide nanoparticles significantly reduces hypoxia, neuroinflammation, and oxidative stress; ultimately reducing levels of amyloid β plaques within the neocortex. Analyses of molecular biomarkers and magnetic resonance imaging‐based functional studies indicate that these effects improve microvessel integrity, cerebral blood flow, and cerebral lymphatic clearance of amyloid β. These changes collectively shift the brain microenvironment toward conditions more favorable to continued neural function as demonstrated by improved cognitive function following treatment. Such multimodal disease‐modifying treatment may bridge critical gaps in the therapeutic treatment of neurodegenerative disease.
Prognostic significance of osteosarcopenia in older adults with colorectal cancer
Authors: Takano Yasuhiro , Kodera Keita , Tsukihara Shu , Takahashi Sumika , Kobayashi Yasunobu , Koyama Muneyuki , Kanno Hironori , Ishiyama Satoshi , Hanyu Nobuyoshi , Eto Ken 
Published: February 2023

AbstractAimOsteopenia and sarcopenia, features of the aging process, are recognized as major health problems in an aging society. This study investigated the prognostic impact of osteosarcopenia, the coexistence of osteopenia and sarcopenia, in older adults undergoing curative resection for colorectal cancer.MethodsWe retrospectively reviewed data of older adults aged 65–98 y who had undergone curative resection for colorectal cancer. Osteopenia was evaluated by bone mineral density measurement in the midvertebral core of the 11th thoracic vertebra on preoperative computed tomography images. Sarcopenia was evaluated by measuring the skeletal muscle cross‐sectional area at the third lumbar vertebra level. Osteosarcopenia was defined as the coexistence of osteopenia and sarcopenia. We explored the relationship of preoperative osteosarcopenia with the disease‐free and overall survival after curative resection.ResultsAmong the 325 patients included, those with osteosarcopenia had significantly lower overall survival rates than those with osteopenia or sarcopenia alone (P < 0.01). In the multivariate analysis, male sex (P = 0.045), C‐reactive protein‐to‐albumin ratio (P < 0.01), osteosarcopenia (P < 0.01), pathological T4 stage (P = 0.023), and pathological N1/N2 stage (P < 0.01) were independent predictors of disease‐free survival, while age (P < 0.01), male sex (P = 0.049), C‐reactive protein‐to‐albumin ratio (P < 0.01), osteosarcopenia (P < 0.01), pathological T4 stage (P = 0.036), pathological N1/N2 stage (P < 0.01), and carbohydrate antigen 19–9 (P = 0.041) were independent predictors of overall survival.ConclusionOsteosarcopenia was a strong predictor of poor outcomes in older adults undergoing curative resection for colorectal cancer, suggesting an important role of osteosarcopenia in an aging society.
Synthesis of BaZrS3 and BaHfS3 Chalcogenide Perovskite Films Using Single‐Phase Molecular Precursors at Moderate Temperatures
Authors: Pradhan Apurva A. , Uible Madeleine C. , Agarwal Shubhanshu , Turnley Jonathan W. , Khandelwal Shriya , Peterson Jonas M. , Blach Daria D. , Swope Ryan N. , Huang Libai , Bart Suzanne C. , Agrawal Rakesh 
Published: February 2023

AbstractChalcogenide perovskites have garnered interest for applications in semiconductor devices due to their excellent predicted optoelectronic properties and stability. However, high synthesis temperatures have historically made these materials incompatible with the creation of photovoltaic devices. Here, we demonstrate the solution processed synthesis of luminescent BaZrS3 and BaHfS3 chalcogenide perovskite films using single‐phase molecular precursors at sulfurization temperatures of 575 °C and sulfurization times as short as one hour. These molecular precursor inks were synthesized using known carbon disulfide insertion chemistry to create Group 4 metal dithiocarbamates, and this chemistry was extended to create species, such as barium dithiocarboxylates, that have never been reported before. These findings, with added future research, have the potential to yield fully solution processed thin films of chalcogenide perovskites for various optoelectronic applications.
Stable Ketenyl Anions via Ligand Exchange at an Anionic Carbon as Powerful Synthons**
Authors: Wei Rui , Wang Xin‐Feng , Ruiz David A. , Liu Liu Leo 
Published: February 2023

AbstractUnder an atmosphere of carbon monoxide (CO), a (phosphino)diazomethyl anion salt [[P]‐CN2][K(18‐C‐6)(THF)] (1) ([P]=[(CH2)(NDipp)]2P; 18‐C‐6=18‐crown‐6; Dipp=2,6‐diisopropylphenyl) undergoes a facile N2/CO exchange reaction giving the (phosphino)ketenyl anion salt [[P]‐CCO][K(18‐C‐6)] (2). Oxidation of 2 with elemental Se affords the (selenophosphoryl)ketenyl anion salt [P](Se)‐CCO][K(18‐C‐6)] (3). These ketenyl anions feature a strongly bent geometry at the P‐bound carbon and this carbon atom is highly nucleophilic. The electronic structure of the ketenyl anion [[P]‐CCO]− of 2 is examined by theoretical studies. Reactivity investigations demonstrate 2 as a versatile synthon for derivatives of ketene, enolate, acrylate and acrylimidate moieties.
Operando Stability of Single‐Atom Electrocatalysts
Authors: Bae Geunsu , Han Sunghoon , Oh Hyung‐Suk , Choi Chang Hyuck 
Published: February 2023

AbstractSingle‐atom catalysts (SACs) are appealing next‐generation catalysts for various electrochemical technologies. Along with significant breakthroughs in their initial activity, SACs now face the next challenge for their viable applications, insufficient operational stability. In this Minireview, we summarize the current knowledge of SAC degradation mechanisms mainly based on Fe−N−C SACs, some of the most investigated SACs. Recent studies on isolated metal, ligand, and support degradations are introduced, and the underlying fundamentals of each degradation path are categorized into active site density (SD) and turnover frequency (TOF) losses. Finally, we discuss the challenges and prospects for the future outlook of stable SACs.
Photo‐responsive cellulose nanocrystal modified fluorinated polyacrylate based on coumarin chemistry
Authors: Zhou Jianhua , Liu Xiuqing , Wang Xueli 
Published: February 2023

AbstractPhoto‐responsive cellulose nanocrystal modified fluorinated polyacrylate was synthesized by environmentally friendly RAFT‐mediated Pickering emulsion polymerization using amphiphilic block copolymer modified cellulose nanocrystal poly(acrylic acid)‐g‐CNC‐g‐poly (hexafluorobutyl acrylate‐co‐7‐(2‐methacryloyloxyethoxy)‐4‐methylcoumarin) PAA‐g‐CNC‐g‐P (HFBA‐co‐CMA) (MCNC) as a stabilizer, and the photo‐responsive coumarin groups were introduced to endow it with self‐healing function. This paper mainly studied the effect of MCNC dosage on emulsion polymerization and latex film properties. The latex particle size and its distribution decreased as the MCNC dosage increased from 0.4 wt% to 1.0 wt%, and then increased afterwards. The mechanical property and thermal stability of latex films could be significantly improved by introducing MCNC. And the surface scratches of latex films with MCNC exceeding 0.4 wt% could be completely repaired after 7 h UV irradiation. Furthermore, the photo‐responsive cellulose nanocrystal modified fluorinated polyacrylate emulsion was applied to fabric finishing by dip‐rolling treatment. And the finished fabric had good hydrophobicity, oleophobicity and surface repair performance.
Influence of E‐beam irradiation on compounds from linear low density polyethylene and thermoplastic vulcanized rubber consisting of a polypropylene and ethylene propylene diene monomer rubber phase
Authors: Krieg David , Sergeieva Olena , Jungkind Sabine , Rennert Mirko , Nase Michael 
Published: February 2023

AbstractLinear low‐density polyethylene (LLDPE) crosslinks under irradiation in the range of up to 250 kGy. Crosslinking leads to better chemical and thermal resistance but causes reduction in mechanical performance. To counter this reduction, compounds of LLDPE with thermoplastic elastomers (TPV) were made. Specimens were irradiated with doses reaching from 99 to 231 kGy. Gel content shows a decrease of around 12% for compounds with 20 wt% of TPV compared to pure LLDPE. It is also found that compounds containing 10 wt% TPV experience a 4% higher gel content than predicted. For higher amounts of TPV elongation at break increases from 689% for pure LLDPE to 769% and tensile strength decreases from 31.9 to 30.5 MPa. Under irradiation, a trend to lower elongations and tensile strengths is observed. Elongation at break decreased around 200% and tensile strength around 5 MPa under irradiation. Thermal analysis of TPV showed that while the melting temperature decreases, its crystallinity first rises for doses up to 165 kGy before decreasing. Infrared spectroscopy was used to identify changes in the chemical structure, where evidence of surface oxidation under irradiation is found for all compounds with LLDPE.
Inverse Electron‐Demanding Diels–Alder Reactions in the Chemical Synthesis of Prenylated Indole Alkaloids Containing a Bicycle[2.2.2]diazaoctane Moiety: A Theoretical Study
Authors: Xu Wenqiang , Sun Tian‐Yu , Di Yingtong , Hao Xiaojiang , Wu Yun‐Dong 
Published: February 2023

AbstractThe Diels–Alder reaction is believed to be a key step in the biosynthesis of prenylated indole alkaloids containing a bicycle[2.2.2]diazaoctane moiety. Many chemical syntheses of bicyclic structures by Diels–Alder reactions have been reported, but the reaction mechanism remains underexplored. We have carried out DFT calculations on both acid‐ and base‐promoted Diels–Alder reactions in these syntheses and reveal that the reactions occur through an inverse‐electron demand mechanism. We hope that the new mechanism is helpful for the mechanistic understanding of the biosynthesis of this class of important natural products.
Non‐approximation‐based outputs stabilization for switched large‐scale nonlinear systems with quantized inputs and sensor uncertainties
Authors: Wang Wanli , Lin Yan 
Published: February 2023

AbstractA non‐approximation‐based output feedback control strategy for a class of switched large‐scale nonlinear systems with quantized inputs and sensor uncertainties is proposed. A dynamic gain, which is shared by the state observers and controllers of all the subsystems, is designed so that the effects of sensor uncertainties, quantized inputs, unknown parameters, and external disturbances can be compensated. By constructing some common Lyapunov functions (CLFs) shared by the switched systems, it is proved that with the proposed scheme, the closed‐loop system stability can be guaranteed under arbitrary switching, and the outputs of all the subsystems can be steered to within arbitrarily small neighborhoods of the origin.
Robust H∞ sliding mode control scheme for uncertain fractional stochastic systems: Nonlinear analysis and design
Authors: Parvizian Majid , Khandani Khosro 
Published: February 2023

AbstractThis paper investigates the
sliding mode control (SMC) design for fractional stochastic systems. We study a very general category of stochastic systems that are nonlinear and driven by fractional Brownian motion (fBm). A robust
SMC scheme is presented for a fractional stochastic model with external disturbance, state‐ and disturbance‐dependent noise, and uncertainties, which ensures that the closed‐loop system is stochastically stable. We propose a novel sliding surface and then prove its reachability in the state space. Furthermore, the conditions for the stochastic stability of the sliding motion are derived via nonlinear Hamilton–Jacobi (HJ)‐type inequalities. In addition, an
SMC method is developed for a special class of fractional stochastic models, and two sets of linear matrix inequality (LMI) conditions are obtained, which are sufficient for stochastic stability. Eventually, the validity of the results is validated via a simulation example.
Antifungal Activity, Structure‐Activity Relationship and Molecular Docking Studies of 1,2,4‐Triazole Schiff Base Derivatives
Authors: Dong Yangming , Li Moucui , Hao Yun , Feng Yunrui , Ren Yinghui , Ma Haixia 
Published: February 2023

AbstractFourteen novel Schiff base compounds (AS‐1∼AS‐14) containing 5‐amino‐1H‐1,2,4‐triazole‐3‐carboxylic acid and substituted benzaldehyde were successfully synthesized, and their structures were verified by melting point, elemental analysis (EA) and spectroscopic techniques (Fourier Transform Infra‐Red (FT‐IR) and Nuclear Magnetic Resonance (NMR)). In vitro hyphal measurements were used to investigate the antifungal activities of the synthesised compounds against Wheat gibberellic, Maize rough dwarf and Glomerella cingulate. The preliminary studies indicated that all compounds had good inhibitory effect on Wheat gibberellic and Maize rough dwarf, among which the compounds of AS‐1 (7.44 mg/L, 7.27 mg/L), AS‐4 (6.80 mg/L, 9.57 mg/L) and AS‐14 (5.33 mg/L, 6.53 mg/L) showed better antifungal activity than that of the standard drug fluconazole (7.66 mg/L, 6.72 mg/L); while inhibitory effect against Glomerella cingulate was poor, only AS‐14 (5.67 mg/L) was superior to that of fluconazole (6.27 mg/L). The research of structure‐activity relationship exhibited that the introduction of halogen elements on the benzene ring and electron withdrawing groups at the 2,4,5 positions on the benzene ring was beneficial to the improvement of the activity against Wheat gibberellic, while the large steric hindrance was not conducive to the improvement of the activity. Additionally, except for AS‐1, AS‐3 and AS‐10, the other compounds had one or several ratio systems to achieve synergistic effect after recombination with pyrimethamine, among which AS‐7 had significant synergistic effect and was expected to be a combinated agent with application prospects. Finally, the molecular docking results of isocitrate lyase with Wheat gibberellic displayed that the presence of hydrogen bonds enabled stable binding of compounds to receptor proteins, and the residues of ARG A: 252, ASN A: 432, CYS A: 215, SER A: 436 and SER A: 434 were the key residues for their binding. Comparing the docking binding energy and biological activity results, it was revealed that the lower the docking binding energy was, the stronger the inhibitory ability of the Wheat gibberellic, when the same position on the benzene ring was substituted.
A soldier's return to duty after minimally invasive correction of complex congenital cardiovascular disease
Authors: Phillips Tarin , Kisling Adam , Gallagher Robert 
Published: February 2023

AbstractWe report a case of incidental detection of severe aortic coarctation, severe secundum atrial septal defect, and bicuspid aortic valve in an active‐duty military service member. A single complex minimally invasive procedure successfully corrected his coarctation and atrial septal defect allowing this patient to continue military service.
Incorporation of Hydrophobic Silica in a Polyvinylidene Fluoride Membrane: Membrane Development and Performance Modeling
Authors: Sze Yin Grace Gan , Aqilah Nur Fatin , Mat Nawi Normi Izati , Mohd Hizam Shafiq , Md Nordin Nik Abdul Hadi , Bilad Muhammad Roil , Adi Putra Zulfan , Jaafar Juhana , Yusof Norhaniza , Hamid Nurfaizey Abdul , Mokhtar Nadzirah Mohd 
Published: February 2023

AbstractMembrane distillation (MD) performance in seawater desalination can be improved by enhancing the material properties (hydrophobicity, porosity) and process parameters (feed flow rate, temperature). In this study, the effects of hydrophobic silica loading on the properties and MD performance of a polyvinylidene difluoride‐based membrane in seawater desalination were investigated, and a sensitivity analysis (temperature gradient, feed flow rate, salinity) was performed. Incorporation of hydrophobic silica improved the hydrophobicity of the membrane. Higher filler loading increased the number of surface pores while maintaining their size. This resulted in improved flux compared with the neat membrane while maintaining high salt rejection. The optimized membrane was 73 % more efficient than the neat membrane.
Assessing Combinations of B(C6F5)3 and N2‐Derived Molybdenum Nitrido Complexes for Heterolytic Bond Activation
Authors: Coffinet Anaïs , Specklin David , Le Dé Quentin , Bennaamane Soukaina , Muñoz Luna , Vendier Laure , Clot Eric , Mézailles Nicolas , Simonneau Antoine 
Published: February 2023

AbstractTwo different dinitrogen‐derived molybdenum nitrido complexes varying by their geometry, ligand spheres and oxidations states were shown to engage their N ligand in dative bonding with the strong Lewis acid B(C6F5)3. The stable adducts were assessed for frustrated Lewis pair‐type heterolytic E−H bond splitting of hydrosilanes (E=Si) and HB(C6F5)2. Whereas Si−H bond activation was achieved, HB(C6F5)2 was shown to substitute B(C6F5)3 in a quantitative or equilibrated fashion, depending on the nature of the nitrido complex. No B−H bond splitting was observed. Thermodynamics of these reactions, computed by DFT, are in agreement with the experimental outcomes.
Is repeat sentinel lymph node biopsy possible for surgical axillary staging among patients with ipsilateral breast tumor recurrence?
Authors: Lu Xunxi , He Mengting , Yu Luoting , Gou Zongchao 
Published: February 2023

AbstractBackgroundThere is a lack of studies assessing the survival of repeat sentinel lymph node biopsy (rSLNB) versus axillary lymph node dissection (ALND) for surgical axillary staging among patients with ipsilateral breast tumor recurrence (IBTR).MethodsWe retrospectively identified patients with IBTR from the Surveillance, Epidemiology, and End Results database from 2000 to 2017. The primary outcome was overall survival (OS) between the rSLNB and ALND groups.ResultsOf the 2141 women with IBTR after lumpectomy and SLNB, 524 did not receive surgical axillary staging (nonsurgery group) and 1617 patients who did undergo axilla surgery received either rSLNB or ALND as axillary staging (1268 with rSLNB and 349 with ALND). The 10‐year OS rates were 61.9% for the nonsurgery and 73.8% for axilla surgery groups (p = .001). In the 1:1 matched cohorts, the 10‐year OS rates were 61.4% for the nonsurgery and 69.1% for axilla surgery groups (p = .072). After adjusting for other factors, axillary surgery treatment of IBTR was an independent favorable factor for OS (hazard ratio [HR], 0.71; 95% CI, 0.56–0.90; p = .004). Within the axilla surgery group, rSLNB presented a comparable 10‐year OS to the ALND cohort (log‐rank test p = .054). Multivariate Cox analysis, as well as subgroup analysis, showed that rSLNB had a similar benefit to ALND (10‐year OS; HR, 1.18; 95% CI, 0.88–1.58; p = .268).ConclusionsThe results of this cohort study suggested that receiving surgical axillary staging was associated with better survival of IBTR patients, and rSLNB had a similar long‐term survival outcome as ALND. rSLNB might be considered for surgical axillary staging among patients with IBTR after lumpectomy and initial SLNB.