bluuebunny/crossref_metadata_2025_split huggingface dataset:
Feasibility study on a longer side-alternating vibration therapy protocol (15 min per session) in children and adolescents with mild cerebral palsy
Authors: Adaikina Alena , Derraik José G. B. , McMillan Janene , Colle Patricia , Hofman Paul L. , Gusso Silmara 
Published: August 2023

ObjectivePrevious studies on side-alternating vibration therapy (sVT) have usually used a 9 min intervention protocol. We performed a feasibility study aimed at assessing the safety, acceptability, and potential effectiveness of a longer sVT protocol (15 min per session) in children and adolescents with cerebral palsy (CP).MethodsFifteen participants aged 5.2–17.4 years (median = 12.4 years) with CP GMFCS level II underwent 20 weeks of sVT consisting of 15 min sessions 4 days/week. Participants were assessed at baseline and after the intervention period, including mobility (six-minute walk-test; 6MWT), body composition (whole-body dual-energy x-ray absorptiometry scans), and muscle function (force plate).ResultsAdherence level to the 15 min VT protocol was 83% on average. There were no adverse events reported. After 20 weeks, there was some evidence for an increase in the walking distance covered in 6MWT (+43 m; p = 0.0018) and spine bone mineral density (+0.032 g/cm2; p = 0.012) compared to baseline.ConclusionsThe 15 min sVT protocol is feasible and well tolerated. The results also suggest potential benefits of this protocol to mobility and bone health. Randomized controlled trials are needed to reliably ascertain the potential effectiveness of a longer sVT protocol on physical function and body composition in young people with CP.
Analysis of adverse drug reactions/events of cancer chemotherapy and the potential mechanism of Danggui Buxue decoction against bone marrow suppression induced by chemotherapy
Authors: Yu Bin , Yan Xida , Zhu Yuanying , Luo Ting , Sohail Muhammad , Ning Hong , Xu Hui 
Published: August 2023

Objective: To analyze the clinical characteristics of adverse reactions/events based on chemotherapy in cancer patients, and then explore the potential mechanism of Danggui Buxue Decoction (DBD) against chemotherapy-induced bone marrow suppression (BMS).Methods: Retrospectively collected and evaluated were the clinical data of patients in a hospital who experienced adverse reactions/events brought on by chemotherapeutic medications between 2015 and 2022. We explored the potential mechanism of DBD against BMS using network pharmacology based on the findings of the adverse reactions/events analysis.Results: 151 instances (72.25%) experienced adverse reactions/events from a single chemotherapy medication. Besides, platinum-based medications produced the most unfavorable effects. The study also found that chemotherapy caused the highest number of cases of BMS, including platinum drugs. Consequently, BMS is the most prevalent adverse reaction disease caused by chemotherapy found in this part. According to network pharmacology findings, DBD can prevent BMS primarily involving 1,510 primary targets and 19 key active ingredients. Based on the enrichment analysis, PI3K-AKT, TNF, MAPK, and IL-17 signaling pathways made up the majority of the DBD-resisting BMS pathways. Molecular docking displayed that kaempferol, the major active ingredient of DBD, had the highest binding energy (−10.08 kJ mol-1) with PTGS2 (a key target of BMS).Conclusion: Cancer patients who received chemotherapy had a risk to develop BMS. Regular blood tests should be performed while taking medicine; early discovery and treatment can reduce a patient’s risk of experiencing adverse reactions/events. Additionally, this study demonstrated that DBD, through a variety of targets and pathways, may be crucial in avoiding BMS.
Management staff’s perspectives on intervention strategies for workplace violence prevention in a tertiary health facility in Nigeria: a qualitative study
Authors: Agu Adaoha Pearl , Azuogu Benedict Ndubueze , Una Alfred F. , Ituma Benard , Eze Irene Ifeyinwa , Onwe Francis I. , Oka Onyinyechukwu Uzoamaka , Igwe-Okomiso Dorathy O. , Agbo Urudinachi N. , Ewah Richard , Uneke Jesse C. 
Published: August 2023

IntroductionHealth workers have increasingly become victims of workplace violence. However, negligible action has been given to developing workplace violence (WPV) prevention programs in hospital settings in low-middle-income countries. An effective workplace violence prevention program is crucial for preventing violence and managing the consequences of incidents. This study assessed management staff perspectives on intervention strategies for workplace violence prevention in a tertiary health facility in Nigeria.MethodsA qualitative study design was employed to explore the intervention strategies for preventing and managing workplace violence at a tertiary health facility in southeast Nigeria. Six focus group discussions were conducted with thirty-eight management-level staff. The interview transcripts were manually coded according to six predefined constructs of workplace violence: creating interdisciplinary harmony and WPV experiences, causes, prevention, program/policy contents, and implementation strategies. A manual thematic analysis approach was adopted, and the results were presented as narratives.ResultsThe findings revealed recognition, welfare, administrative control, and security as vital strategies for the WPV prevention program. The participants agreed that unanimity among staff could be promoted through respect for all cadres of staff and for people’s perspectives (creating interdisciplinary harmony). Assaults and staff intimidation/victimization (experiences), attributed to unethical/poor health workers’ behaviour and ethnic discrimination (causes), were viewed as preventable by ensuring patients’/caregivers’ welfare through respectful and timely care and staff’s welfare through incentives/remunerations and discouraging intimidation (prevention strategies). Furthermore, the staff expressed that the WPV program should employ administrative controls, including instituting WPV policy/unit, codes of ethics, and standard operating procedures across all workplace facets (program/policy contents), which should be implemented through awareness creation, enforcement of sanctions, and provision of appropriate and adequate security presence in the hospital (policy implementation strategies).ConclusionRespect, patient/staff welfare, administrative control, and security are strong mechanisms to prevent workplace violence in tertiary hospitals. Hospital management should institutionalize workplace violence prevention programs/policies and ensure compliance.
Розробка UX/UI дизайну сайту факультету мистецтв ХНПУ імені Г.С. Сковороди
Authors: Житєньова Наталя 
Published: August 2023

В роботі розглянуто тенденції UX/UI дизайну освітніх сайтів закладів вищої освіти в Україні. Проаналізовано сайти факультетів мистецької освіти щодо юзабіліті та структурних елементів. Виокремлено необхідні аспекти для розробки дизайну сайту факультету мистецтв Харківського національного педагогічного університету імені Г.С. Сковороди. Використовувалися такі методи дослідження, як предметно-аналітичний для вивчення структурних та ілюстративних джерел; термінологічний прийом для однозначного розуміння істотних ознак дизайну; психологічний метод вербального визначення характеру зорового відчуття від фінальної стадії розробки дизайну сайту.
Наукова новизна статті полягає в комплексному аналізі освітніх сайтів ЗВО України у напрямку мистецької освіти. Виявленні сучасних тенденцій UX/UI дизайну у розробці сайтів мистецького спрямування. Виокремленні необхідних структурних елементів розробки сайту факультету мистецтв Харківського національного педагогічного університету імені Г.С. Сковороди.
Результати дослідження довели, що для розробки UX/UI дизайну сайту факультету мистецтв ХНПУ імені Г.С. Сковороди необхідно використовувати різні структурні елементи такі як: емоційний дизайн (використання візуально «живих» елементів для спонукання виникнення почуттів та реакції від користувачів); геометрична структура (використання класичних геометричних елементів для акцентуації); дизайн із розділеним екраном (використання умовно розділеного екрану на дві панелі контенту, що згортається у вертикальний блок в адаптивному дизайну); збільшення змісту тексту (повернення багаторівневих заголовків тощо); нові шрифти (уникнення класики і використання засічок, зміна розміру від слова до слова, використання напівпрозорого шрифту із перекриттям непрозорого, додавання жирного та курсивного нарису); адаптація під нові гаджети (забезпечення якісними збільшеними зображеннями для адаптивного дизайну); унікальна мікровзаємодія (наявність тактильних оглядів у адаптивному дизайні, тобто можливість змінювати відтінок для різних станів програми, візуалізацію завантаження потрібної сторінки, додавання анімації під час переходу, наявність оригінальної реакції на натискання певних кнопок на сайті).
PENETAPAN KADAR FENOLIK DAN FLAVONOID FRAKSI DAUN INSULIN (Smallanthus sonchifolius) SECARA SPEKTROFOTOMETRI UV-Vis
Authors: Saputri Alip Desi Suyono , Sa'ad Muhammad 
Published: August 2023

Indonesia merupakan negara kaya akan sumber daya alam nabati yang banyak digunakan sebagai alternatif pengobatan. Salah satunya tanaman insulin (Smallanthus soncifolius). Tanaman insulin memiliki kandungan senyawa kimia yang berkhasiat bagi kesehatan tubuh (Amanatie et al., 2015). Antara lain flavonoid dan fenol, yang bertanggungjawab terhadap aktivitas antibakteri pada bakteri Staphylocpcus aureus dengan diameter zona hambat sebesar 2,528 mm pada konsentrasi 15% (Ramonah et al., 2020). Tujuan penelitian untuk mengetahui kadar total flavonoid dan fenolik dari fraksi air, etil asetat dan n-heksan pada daun insulin. Metode penetapan kadar flavonoid dan fenolik total menggunakan spektrofotometri UV-Vis pada panjang gelombang 350-500nm untuk senyawa flavonoid dan 760nm untuk senyawa fenolik serta operating time pada 0 sampai 60 menit. Baku pembanding yang digunakan penelitian ini yaitu asam galat sebagai baku penetapan kadar fenolik dan kuersetin sebagai baku penetapan kadar flavonoid total. Hasil penelitian diperoleh kadar fenolik pada fraksi n-heksan sebesar 0,45975 mgGAE/100ml, etil asetat sebesar 0,716428 mgGAE/100ml dan fraksi air sebesar 0,37866 mgGAE/100ml dengan. Kadar flavonoid total dari fraksi etil asetat, sebesar 4,20964 % mgQE/100ml, fraksi n-Heksan yaitu 4,02734% mgQE/100ml dan fraksi air yaitu 3,66276 mgQE/100ml. Berdasarkan hasil tersebut dapat disimpulkan kadar flavonoid total dan fenolik tertinggi terdapat pada fraksi etil asetat dibandingkan dengan fraksi lainnya.
Methodological aspects of assessing the scale of IUU fishing in inland water bodies by the example of individual regions of Russia
Authors: Leontiev S. Yu. , Piyanova S. V. , Ulchenko V. A. , Kamshukov S. V. 
Published: August 2023

Purpose of work: comparative analysis of the available methodological approaches to the assessment of the amount of commercial fish species taken by IUU fishing and IUU bycatch in the implementation of fisheries on the example of individual regions of the Russian Federation, including inland water bodies of different fishery basins. Methods used: comparative analysis of methodological materials on assessment of IUU fishing, used in different branches of VNIRO. Novelty: for the first time an analysis of various methods for assessing the extraction of commercial fish species by IUU fishing has been conducted; the presented generalized data on the assessment of illegal catches in different fishery basins of the Russian Federation show that the amount of IUU fishing is the volume which often exceeds the values of the total allowable catches (TAC) and the recommended volumes of production (catch) of aquatic bioresources. Practical significance: Refinement of methodical approaches of estimation of IUU fishing and IUU bycatch will allow receiving a characteristic picture of size of IUU fishing for various fishery basins taking into account specifics of fishery basins, species composition of catches and applied gears of catch. The resulting data on the value of IUU-catch of commercial fish species will be used to clarify (adjust) the projected volume of production (catch) of commercial fish in Russia.
On the Improvement of Pink Salmon Fishery Management (on the Sakhalin- Kuril Region as an example)
Authors: Kaev A. M. , Samarsky V. G. , Glubokovsky M. K. 
Published: August 2023

Purpose: Assess the current state of the pink salmon fishery management and determine ways to improve the scientific support of the pink salmon fishing to ensure the rational usage of its stocks. Methods used: Analysis of historical data and methods used to assess the state of pink salmon stocks and develop recommendations for their usage. Results: Over the past decade, discrepancies between expected and actual returns of pink salmon, to the eastern coast of Sakhalin in particular, have averaged more than double. Those inconsistencies are associated both with many uncertainties in the development of forecasts and with the representativeness of the data used. Wrong estimates form the basis of the submitted fishing strategies, which negatively affects operational fishing management. Using the returns of pink salmon in 2021–2022 as an example, it is shown that the accuracy of forecasting could be higher when using standardized primary data, for which it is necessary to restore the corresponding database, the support of which was interrupted in 2015. It is also proposed to focus on strengthening operational forecasting as a basis for the development of fishery management measures. Practical significance: Restoration of the primary database and return to previously well-established methods of fishery management should increase the effectiveness of scientific part in pink salmon fishery of the region.
A Single-Event Transient (SET) Tolerant Dynamic Bias Comparator in 65-nm CMOS
Authors: Ash Andrew , Hu John 
Published: August 2023

<p>A single-event transient (SET) tolerant dynamic bias comparator leveraging path-splitting is presented in this paper. The dynamic bias structure with a tail capacitor is found to be vulnerable to positive and negative SET transients. A negative transient on the tail transistor doubles the energy per conversion. A positive transient on the tail MOS capacitor reduces the preamplifier gain by 35.7%, which increases the metastability error rate in the subsequent latch. A path splitting technique is applied to mitigate the positive SET. Simulations in a 65-nm CMOS process showed that a two path split can recover the comparator output voltage swing by 12.7%. Compared with the state-of-the-art CMOS radiation-hardened by design (RHBD) dynamic comparators, this circuit achieved the lowest energy per comparison while maintaining low input referred noise and gaining SET tolerance in the evaluation phase. </p>
Em Homenagem ao PPGG pelos seus 50 Anos: Relatos e Comentários
Authors: Marques Jorge Soares 
Published: August 2023

Em caráter de homenagem, este trabalho apresenta uma contribuição de comentários e relatos sobre os 50 anos do Programa de Pós-Graduação em Geografia (PPGG) da Universidade Federal do Rio de Janeiro (UFRJ). Destaca a atuação dos professores que criaram e contribuíram para uma trajetória importante e de sucesso na formação no Brasil de Mestres e Doutores em Geografia.
A Geoinformação na Pesquisa em Geografia no Contexto do PPGG/UFRJ
Authors: De Menezes Paulo Márcio Leal , Cruz Carla Bernadete Madureira , Fernandes Manoel Do Couto 
Published: August 2023

A geoinformação sempre fez parte de nossa vida, acompanhando-nos em toda nossa evolução civilizatória. Atualmente, ela ganha destaque pois se apresenta como parte do cotidiano social, refletindo-se em diferentes cenários de planejamento e gestão nos mais diversos segmentos sociais, políticos, econômicos e ambientais. A necessidade da utilização de modelos de análise espaciais e temporais, inerentes à ciência geográfica, foi o atrativo para o desenvolvimento das pesquisas de geoinformação no âmbito do Programa de Pós-Graduação em Geografia da UFRJ (PPGG/UFRJ). O presente artigo busca apresentar uma leitura histórica de pesquisas desenvolvidas no PPGG/UFRJ, resgatando os primeiros passos do geoprocessamento no Brasil, à luz de pesquisadores do PPGG, além de apresentar a contribuição de pesquisas na área da geoinformação que vêm sendo desenvolvidas ao longo dos 50 anos do programa. Como conclusão é apresentada uma reflexão sobre esse histórico e as perspectivas de consolidação do PPGG/UFRJ como um polo de pesquisas nacional e internacional da Geoinformação.
Identificação de Áreas de Eucalipto a Partir de Segmentação Espacial e Temporal de Série Temporal Landsat
Authors: Ferraz Debora Da Paz Gomes Brandão , Sanchez Vicens Raul 
Published: August 2023

A conversão de sistemas naturais em sistemas antropizados vem causando sobrecarga nos ecossistemas e alterações na paisagem. O Brasil é um dos maiores praticantes da silvicultura, mas as informações sobre o setor são bastante conflitantes. É necessário entender como essas mudanças ocorrem e o Sensoriamento Remoto multitemporal emerge como ferramenta de análise. O objetivo do presente trabalho é testar uma metodologia de detecção de áreas de eucalipto utilizando o algoritmo LandTrendr na plataforma Google Earth Engine combinado com análise orientada a objetos a partir da série temporal do satélite Landsat, entre 1985 e 2020, e identificar a idade dos segmentos encontrados utilizando o mesmo. A matriz de confusão mostrou uma acurácia global de 0.990 com o algoritmo Area² e um Kappa de 0.959, apresentando um resultado bastante satisfatório. Já a identificação da moda do primeiro ano de ganho de cada segmento obteve um Kappa de 0.643.
Análise das Diferenças de Identificação e Delimitação de Áreas Verdes Intraurbanas do Rio de Janeiro pela Perspectiva em Mesoescala do MapBiomas
Authors: Pedreira João Pedro Das Neves Cardoso , Cruz Carla Bernadete Madureira 
Published: August 2023

Contribuindo com a qualidade ambiental na paisagem urbana, as áreas verdes apresentam funções aliadas ao resgate de espaços coletivos nas cidades. Através do Sensoriamento Remoto e de Sistemas de Informações Geográficas é possível mapear e monitorar o verde urbano em diferentes escalas. A iniciativa MapBiomas apresenta potencial para acompanhar a evolução anual da cobertura e uso da terra em todo o território nacional, sendo um desafio a adaptação desta base para escalas em nível municipal. Neste sentido, o presente trabalho busca analisar o verde urbano na cidade do Rio de Janeiro, trazendo uma avaliação da representatividade destes dados e análises referentes à dimensão e distribuição espacial das áreas verdes em seu contexto. Apesar da escala de representação não ser ideal, o uso deste conjunto de dados justifica-se pela riqueza de 35 anos de mapas anuais. Os dados também viabilizam diagnósticos socioambientais, como a elaboração do Índice e do Percentual de Áreas Verdes, que no município alcançaram em 2014 valores de 49,46 m²/habitantes e 26,05%, respectivamente.
MOTIVASI SISWA DALAM MENGIKUTI KEGIATAN EKSTRAKURIKULER SEPAK BOLA DI SMP PEMDES TOROH GROBOGAN TAHUN 2022
Authors: Adiwangsa Dewandaru  , Arif Rohman Hakim  , Agustanico Dwi Muryadi  
Published: August 2023

Tujuan dari penelitian ini adalah untuk mengetahui motivasi siswa dalam mengikuti kegiatan ekstrakurikuler sepak bola di SMP Pemdes Toroh Grobogan, mengetahui faktor-faktor yang mempengaruhi motivasi siswa dalam mengikuti kegiatan ekstrakurikuler sepak bola, dan memberi masukan bagi siswa bahwa motivasi merupakan salah satu faktor penting yang dapat mempengaruhi prestasi. Metode penelitian yang digunakan adalah deskriptif kuantitatif. Subyek dalam penelitian ini adalah siswa yang mengikuti ekstrakurikuler sepak bola di SMP Pemdes Toroh Grobogan Tahun 2022. Teknik pengumpulan data yang digunakan dalam penelitian ini adalah angket kuesioner. Teknik analisis data menggunakan teknik analisis deskriptif kuantitatif yang dituangkan dalam bentuk persentase. Berdasarkan hasil analisis data dan pembahasan dapat diambil kesimpulan, bahwa motivasi siswa dalam mengikuti ekstrakurikuler sepak bola di SMP Pemdes Toroh Grobogan berada pada kategori “sangat rendah” sebesar 4,44% (2 siswa), “rendah” sebesar 1,11% (5 siswa), “cukup” sebesar 1,11% (2 siswa), “tinggi” sebesar 60% (27 siswa), dan “sangat tinggi” sebesar 13,33% (6 siswa).
Bartter Syndrome: A Case Report
Authors: Supriyani Yayik , Deka Viotra  , Putri Deas Hadilofyani  
Published: August 2023

Background: Bartter's syndrome refers to a group of genetic disorders that affect the renal tubular system, which is responsible for reabsorbing various substances such as sodium, potassium, and chloride from the urine into the blood. This study aimed to present a clinical case related to Bartter syndrome.
Case presentation: A 52-year-old male patient in the internal medicine department of Dr. M. Djamil General Hospital Padang with the main complaint of weakness in both legs increasing since 1 day ago. On laboratory examination, the patient found potassium 1.7 mmol/L, indicating hypokalemia. Renal function examination showed normal kidney function. Examination of blood gas analysis showed results of metabolic alkalosis. Examination of urine potassium obtained potassium levels of 22 mmol/day, urine osmolarity of 140 mOsm/kgH2O at serum osmolarity of 274 mOsm/kgH2O, with TTKG (transtubular potassium gradient) = 28. The patient was diagnosed with Bartter syndrome. Treatment is carried out by administering KSR tablets 3x600 mg orally while monitoring electrolytes regularly.
Conclusion: This patient has hypokalemia, metabolic alkalosis, normal magnesium and calcium, and hypercalciuria. This patient is diagnosed with Bartter syndrome.
Infiltration Between Popliteal Artery and Capsule of the Knee Combined with Adductor Canal Block as Analgesic Adjuvant During and Postoperative in Total Knee Replacement Surgery
Authors: Mahardika David Rendra , Tjokorda Gede Agung Senapathi  , I Made Subagiartha  
Published: August 2023

Background: Infiltration between the popliteal artery and capsule of the knee (iPACK) is one method that has been proposed in recent years as a potential alternative to peripheral nerve block as analgesia in total knee replacement (TKR) procedures. This study presents anesthetic management using spinal anesthesia combined with iPACK and adductor canal block (ACB) in patients with grade IV osteoarthritis who underwent TKR of the right knee.
Case presentation: A woman, a housewife aged 50 years, was planning to undergo TKR surgery. The patient came with complaints of pain in the right knee 1 year before entering the hospital. The patient was given supplemental oxygen with a nasal cannula at 3 liters per minute. Prior to spinal anesthesia, the patient was given fentanyl 25 mcg iv, ketamine 10 mg iv, and midazolam 1.5 mg IV as premedication. The patient was positioned on the right side, and a 27G Quincke needle was inserted at the level of L3-L4 and given bupivacaine heavy 0.5% 7.5 mg, then lateralized for 15 minutes. After lateralization, the patient was positioned supine and used ultrasound to direct ACB action with a regimen of ropivacaine 0.25% + dexamethasone 5 mg a volume of 20 ml, then iPACK was performed with a regimen of Ropivacaine 0.375% + dexamethasone 5 mg a volume of 20 ml. After surgery, the patient is treated in the recovery room for 1 hour until bromage score is 0. The patient received the PCA Morphine analgesic demand only 1 mg/mL, 1 mg per dose, max 5 mg over 4 hours, lockout interval 6 minutes; Paracetamol 500 mg every 6 hours PO; Ibuprofen 400 mg every 8 hours PO.
Conclusion: TKR patients who were given analgesia using the ACB peripheral nerve block technique combined with iPACK experienced a decrease in pain levels and lower use of postoperative morphine so that patient mobilization was faster and reduced the patient's length of stay.