bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE SITUATION OF SHARPS INJURIES AMONG IN MEDICAL STAFFS AT DUC GIANG GENERAL HOSPITAL IN 2022
Authors: Huy Nga Nguyen , Tuong Vy Mai , Van Xuyen Dang , Tuan Anh Tran 
Published: April 2023

The study aimed to: (1) Describe the situation of damage caused by sharp waste in medical staffs and (2) Identify association factors at Duc Giang General Hospital in 2022. The study is a cross-sectional descriptive research on 121 health care workers. The results showed that 24,8% of healthcare workers injuried by medical sharp waste, of which the wounds on finger and hand accounted for the most with 96,7%, the skin and mucous lesions wounds accounted for the majority with 63,3%, the damage related to patients who may have HIV, hepatitis B other infectious diseases accounted for 16,7%, 13.3% and 30%, respectively. Factors associated with sharp waste injury in healthcare workers include age, training in medical solid waste, and knowledge of medical solid waste management (p<0.05). Conclusion: The rate of damage caused by sharp waste among healthcare workers is still high, especially among young people, those who have not been trained in medical waste, and those with poor knowledge of medical waste management.
EVALUATION THE RESULTS OF PHAKIC ICL SURGERY AFTER ONE MONTH IN 23 PATIENTS AT SAIGON - CAN THO EYE HOSPITAL FROM JULY 2020 TO DECEMBER 2021
Authors: Van Ket Tran , Quoc Tung Mai , Viet Phap Le 
Published: April 2023

Objectives: To evaluate the results of Phakic ICL surgery after one month at Saigon Can Tho Eye Hospital. Subjects and methods: A retrospective descriptive study evaluated one-month results in 45 eyes of 23 patients undergoing Phakic ICL surgery with Visian Staar Lens of Staar Surgical Company, from July 2020 to December 2021. Ocular biometry was evaluated using the Anterior Chamber Depth index (ACD), the White-to-White measurement (WTW), and the Vault index. Patient satisfaction was evaluated using a visual analogue scale ranging from 0 (very dissatisfied) to 10 (very satisfied). Results: The pre- and postoperative equivalent sphericalness were: -9.26 ± 2.91 (-16 to -3.75) and -1.15 ± 1.06, respectively, which was statistically significant (P<0.0001). The number of incremental postoperative glassless visual rows after 1-week and 1-month surgery were 7.16 and 7.25 rows, respectively. Patient satisfaction was 96%. No postoperative complication was reported. Conclusions: Phakic ICL surgery is highly effectively, safely, and accurately in treatment of refractive errors, including nearsightedness and astigmatism, which results in very good vision after surgery. Patient satisfaction was very high (96%). Phakic ICL could minimize postoperative dry eyes. The techinique is simple and quick technique with simple postoperative care but requires high precision.
PERCEIVED ORGANIZATIONAL SUPPORT AS A PANACEA FOR GOOD EMPLOYEE PERFORMANCE: A BANKING CONTEXT
Authors: Agbasi Obianuju Emmanuela  , Onyekwelu Njideka Phina  , Nwosu Chike  
Published: April 2023

Perceived Organization Prestige (POS) defines how employees feel that the organization(s) they work in appreciate and value their effort, and hence determines their performance and that of the organization at large. Therefore, this study examined POS as measured by employee recognition and how it impacts employees' task performance in selected deposit money banks in Southeast Nigeria. A survey research design was adopted by the study. A total of 10 banks were selected for this study with a population of 789 and it had a sample size of 257. A structured questionnaire was used in data collection and analyzed using correlation analysis, while the hypothesis was tested at a 5% level of significance. Findings showed that employee recognition has a statistically significant positive nexus with task performance in the selected deposit money banks in South East Nigeria (r = .974, p-value < 0.05). It is, therefore, concluded that POS is positively and significantly related to employee task performance. The study recommended that the management of the studied banks need to be recognizing exceptional performance in the presence of others as it will motivate them to continue while encouraging others to put in more effort so as to also get recognized.
Keywords: Perceived Organizational Support, Employee Task Performance, Employee Recognition, Banks and Nigeria.
Life Science Research and Drug Discovery at the Turn of the 21st Century: The Experience of SwissBioGrid
Authors: Den Besten Matthijs , Thomas Arthur J. , Schroeder Ralph 
Published: April 2023

Background
It is often said that the life sciences are transforming into an information science. As laboratory experiments are starting to yield ever increasing amounts of data and the capacity to deal with those data is catching up, an increasing share of scientific activity is seen to be taking place outside the laboratories, sifting through the data and modelling “in silico” the processes observed “in vitro.” The transformation of the life sciences and similar developments in other disciplines have inspired a variety of initiatives around the world to create technical infrastructure to support the new scientific practices that are emerging. The e-Science programme in the United Kingdom and the NSF Office for Cyberinfrastructure are examples of these. In Switzerland there have been no such national initiatives. Yet, this has not prevented scientists from exploring the development of similar types of computing infrastructures. In 2004, a group of researchers in Switzerland established a project, SwissBioGrid, to explore whether Grid computing technologies could be successfully deployed within the life sciences. This paper presents their experiences as a case study of how the life sciences are currently operating as an information science and presents the lessons learned about how existing institutional and technical arrangements facilitate or impede this operation.
Results
SwissBioGrid gave rise to two pilot projects: one for proteomics data analysis and the other for high-throughput molecular docking (“virtual screening”) to find new drugs for neglected diseases (specifically, for dengue fever). The proteomics project was an example of a data management problem, applying many different analysis algorithms to Terabyte-sized datasets from mass spectrometry, involving comparisons with many different reference databases; the virtual screening project was more a purely computational problem, modelling the interactions of millions of small molecules with a limited number of protein targets on the coat of the dengue virus. Both present interesting lessons about how scientific practices are changing when they tackle the problems of large-scale data analysis and data management by means of creating a novel technical infrastructure.
Conclusions
In the experience of SwissBioGrid, data intensive discovery has a lot to gain from close collaboration with industry and harnessing distributed computing power. Yet the diversity in life science research implies only a limited role for generic infrastructure; and the transience of support means that researchers need to integrate their efforts with others if they want to sustain the benefits of their success, which are otherwise lost.
Tracking the Current Rise of Chinese Pharmaceutical Bionanotechnology
Authors: Lenoir Tim , Herron Patrick 
Published: April 2023

Background: The Context and Purpose of the Study

Over the last decade China has emerged as a major producer of scientific publications, currently ranking second behind the US. During that time Chinese strategic policy initiatives have placed indigenous innovation at the heart of its economy while focusing internal R&D investments and the attraction of foreign investment in nanotechnology as one of their four top areas. China’s scientific research publication and nanotechnology research publication production has reached a rank of second in the world, behind only the US. Despite these impressive gains, some scholars argue that the quality of Chinese nanotech research is inferior to US research quality due to lower overall times cited rates, suggesting that the US is still the world leader. We combine citation analysis, text mining, mapping, and data visualization to gauge the development and application of nanotechnology in China, particularly in biopharmananotechnology, and to measure the impact of Chinese policy on nanotechnology research production.

Results, the main findings
Our text mining-based methods provide results that counter existing claims about Chinese nanotechnology research quality. Due in large part to its strategic innovation policy, China’s output of nanotechnology publications is on pace to surpass US production in or around 2012.A closer look at Chinese nanotechnology research literature reveals a large increase in research activity in China’s biopharmananotechnology research since the implementation in January, 2006 of China’s Medium & Long Term Scientific and Technological Development Plan Guidelines for the period 2006-2020 (“MLP”).

Conclusions
Since the implementation of the MLP, China has enjoyed a great deal of success producing bionano research findings while attracting a great deal of foreign investment from pharmaceutical corporations setting up advanced drug discovery operations. Given the combination of current scientific production growth as well as economic growth, a relatively low scientific capacity, and the ability of its policy to enhance such trends, China is in some sense already the new world leader in nanotechnology. Further, the Chinese national innovation system may be the new standard by which other national S&T policies should be measured.
Concepts and Synonymy in the UMLS Metathesaurus
Authors: Merrill Gary 
Published: April 2023

This paper advances a detailed exploration of the complex relationships among terms, concepts, and synonymy in the UMLS Metathesaurus,
and proposes the study and understanding of the Metathesaurus from a model-theoretic perspective.
Initial sections provide the background and motivation for such an approach, and a careful informal treatment of these notions is offered as a context and basis for the formal analysis.
What emerges from this is a set of puzzles and confusions in the Metathesaurus and its literature pertaining to synonymy and its relation to terms and concepts.
A model theory for a segment of the Metathesaurus is then constructed, and its adequacy relative to the informal treatment is demonstrated.
Finally, it is shown how this approach clarifies and addresses the puzzles educed from the informal discussion, and how the model-theoretic perspective may be employed to evaluate some fundamental criticisms of the Metathesaurus.
Recall and bias of retrieving gene expression microarray datasets through PubMed identifiers
Authors: Piwowar Heather , Chapman Wendy 
Published: April 2023

Background: The ability to locate publicly available gene expression microarray datasets effectively and efficiently facilitates the reuse of these potentially valuable resources. Centralized biomedical databases allow users to query dataset metadata descriptions, but these annotations are often too sparse and diverse to allow complex and accurate queries. In this study we examined the ability of PubMed article identifiers to locate publicly available gene expression microarray datasets, and investigated whether the retrieved datasets were representative of publicly available datasets found through statements of data sharing in the associated research articles.
Results: In a recent article, Ochsner and colleagues identified 397 studies that had generated gene expression microarray data. Their search of the full text of each publication for statements of data sharing revealed 203 publicly available datasets, including 179 in the Gene Expression Omnibus (GEO) or ArrayExpress databases. Our scripted search of GEO and ArrayExpress for PubMed identifiers of the same 397 studies returned 160 datasets, including six not found by the original search for data sharing statements. As a proportion of datasets found by either method, the search for data sharing statements identified 91.4% of the 209 publicly available datasets, compared to only 76.6% found by our search carried out using PubMed identifiers. Searching GEO or ArrayExpress alone retrieved 63.2% and 46.9% of all available datasets, respectively. There was no difference in the type of datasets found by PubMed identifier searches in terms of research theme or the technology used. However, the studies identified were more likely to have larger sample sizes, were more frequently cited, and published in higher impact journals. Conclusions: Searching database entries using PubMed identifiers can identify the majority of publicly available datasets, but caution is required when this method is used to collect data for policy evaluation since studies in low impact journals are disproportionately excluded. We urge authors of all datasets to complete the citation fields for their dataset submissions once publication details are known, thereby ensuring their work has maximum visibility and can contribute to subsequent studies.
NEMO: Extraction and normalization of organization names from PubMed affiliations
Authors: Jonnalagadda Siddhartha Reddy , Topham Philip 
Published: April 2023

Background: We are witnessing an exponential increase in biomedical research citations in PubMed. However, translating biomedical discoveries into practical treatments is estimated to
take around 17 years, according to the 2000 Yearbook of Medical Informatics, and much information is lost during this transition. Pharmaceutical companies spend huge sums to identify opinion leaders and centers of excellence. Conventional methods such as literature search, survey, observation, self‐identification, expert opinion, and sociometry not only need much human effort, but are also non‐comprehensive. Such huge delays and costs can be reduced by “connecting those who produce the knowledge with those who apply it”. A humble step in this direction is large‐scale discovery of persons and organizations involved in specific areas of research. This can be achieved by automatically extracting and disambiguating author names and affiliation strings retrieved through Medical Subject Heading (MeSH) terms and other keywords associated with articles in PubMed. In this study, we propose NEMO (Normalization Engine for Matching Organizations), a system for extracting organization names from the affiliation strings provided in PubMed abstracts, building a thesaurus (list of synonyms) of organization names, and subsequently normalizing them to a canonical organization name using
the thesaurus.
Results: We used a parsing process that involves multi‐layered rule matching with multiple dictionaries. The normalization process involves clustering based on weighted local sequence
alignment metrics to address synonymy at word level, and local learning based on finding connected components to address synonymy. The graphical user interface and java client library
of NEMO are available at http://lnxnemo.sourceforge.net.
Conclusion: NEMO associates each biomedical paper and its authors with a unique organization name and the geopolitical location of that organization. This system provides more accurate
information about organizations than the raw affiliation strings provided in PubMed abstracts. It can be used for : a) bimodal social network analysis that evaluates the research relationships
between individual researchers and their institutions; b) improving author name disambiguation; c) augmenting National Library of Medicine (NLM)’s Medical Articles Record
System (MARS) system for correcting errors due to OCR on affiliation strings that are in small fonts; and d) improving PubMed citation indexing strategies (authority control) based on
normalized organization name and country.
EpiphaNet: An Interactive Tool to Support Biomedical Discoveries
Authors: Cohen Trevor , Whitfield G Kerr , Schvaneveldt Roger W , Mukund Kavitha , Rindflesch Thomas 
Published: April 2023

Background. EpiphaNet (http://epiphanet.uth.tmc.edu) is an interactive knowledge discovery system, which enables researchers to explore visually sets of relations extracted from MEDLINE using a combination of language processing techniques. In this paper, we discuss the theoretical and methodological foundations of the system, and evaluate the utility of the models that underlie it for literature‐based discovery. In addition, we present a summary of results drawn from a qualitative analysis of over six hours of interaction with the system by basic medical scientists.
Results: The system is able to simulate open and closed discovery, and is shown to generate associations that are both surprising and interesting within the area of expertise of the researchers concerned.
Conclusions: EpiphaNet provides an interactive visual representation of associations between concepts, which is derived from distributional statistics drawn from across the spectrum of biomedical citations in MEDLINE. This tool is available online, providing biomedical scientists with the opportunity to identify and explore associations of interest to them.
Legislative base for regulation of the number of hunting resources on the example of the Leningrad Region
Authors: Chekhovskikh I. A. , Ol E. M. 
Published: April 2023

Federal Law No. 209-FZ of July 24, 2009 “On hunting and on the conservation of hunting resources and on amendments to certain legislative acts of the Russian Federation” establishes the basis for regulating the number of hunting resources, which are specified by subordinate regulatory legal acts and norms of veterinary legislation.The article discusses the requirements that determine the procedure for organizing and conducting activities to regulate the number of hunting resources, explains the essence and necessity of this activity, provides materials and research methods. Particular attention is paid to the condition of the hunting resources of the Leningrad Region and the justification for the need to regulate their numbers in accordance with regional environmental and economic needs.
On the issue of licensing pharmaceutical activities carried out in the field of circulation of medicinal products for veterinary use
Authors: Zakhodnova D. V. , Poyarkova R. V. , Shershneva I. I. 
Published: April 2023

The article analyzes data on the provision of public services for licensing pharmaceutical activities in the field of circulation of medicines for veterinary use.Studied regulatory legal documents on the procedure for licensing. The register of licensees and making appropriate changes to it is maintained by the Federal Service for Veterinary and Phytosanitary Surveillance. In accordance with the established procedure, the Service provides interested persons with information from the Register and other information in this field of activity. Through the Unified Portal of Public Services of the Federal State Information System, applications for the provision of licenses are sent. In electronic form, a request is also made to the licensing authority to amend the Register and terminate the licenses. The use of EPGU for this purpose was introduced from March 1, 2022.The data of the North-Western Interregional Department of Rosselkhoznadzor in the assigned field of activity for granting licenses, suspension of their validity, renewal and termination of licenses are analyzed.
Antibiotic resistance of Klebsiella pneumoniae and practical significance for veterinary medicine
Authors: Makavchik S. A. , Borisova M. S. 
Published: April 2023

For successful pharmacotherapy of animals, species identification of pathogens, analysis of antibiograms and interpretation of the results, and laboratory monitoring of the mechanisms of antibiotic resistance are important. This is necessary for veterinarians to rationally select antibacterial drugs and predict their clinical effectiveness. In veterinary clinics, antimicrobial therapy requires review of therapeutic efficacy more often than other treatments.Klebsiella are widely distributed in nature. These microorganisms are often etiological factors in septicemia in cattle, birds, horses, pigs, as well as in the development of infectious diarrhea in young farm animals.The purpose of the study is to study the antimicrobial resistance of Klebsiella pneumoniae isolated from dogs and its practical significance for veterinary medicine.Materials and methods. The microorganism K. pneumoniae was isolated from wound contents in a dachshund dog. The dog was observed in the intensive care unit in the veterinary clinic.The sensitivity to antibacterial drugs was assessed by the method of diffusion of antibiotics into agar.Research results. In the period from 2021 to 2022, a total of 100 isolates were isolated from dogs with purulentinflammatory processes, among which 18% are gram-negative and 82% are gram-positive microorganisms, and the case of Klebsiella pneumoniae isolation is 1%.The isolates of Klebsiella pneumonia were characterized by resistance to aminoglycosides (gentamicin, tobramycin, amikacin), III generation cephalosporins (cefotaxime, ceftriaxone, ceftazidime), IV cephalosporins (cefepime), penicillins (Amoxicillin/clavulanic acid), carbapenems (imipenem, meropenem, doripenem, ertapenem). ), fluoroquinolones (ciprofloxacin, ofloxacin, levofloxacin, moxifloxacin), aminoglycosides (gentamicin, amikacin, tobramycin) and a number of other antimicrobial drugs (sulfamethoxazole trimethoprim). Klebsiella was highly sensitive only to fosfomycin.When analyzing this antibiogram of Klebsiella pneumoniae, it is necessary to conduct additional laboratory studies in order to establish the minimum inhibitory concentrations of antibiotics and to study the mechanisms of resistance.Conclusion. Among strains of Klebsiella pneumoniae isolated from wound exudate in dogs, there is a spread of resistance to most antibiotics, as well as an increase in resistance to cephalosporins and carbapenems. It is necessary to carry out laboratory control of antibiotic resistance for further rational use of antibacterial drugs.