bluuebunny/crossref_metadata_2025_split huggingface dataset:
Treatment of iron deficiency in patients scheduled for pancreatic surgery: implications for daily prehabilitation practice in pancreatic surgery
Authors: Wijma Allard G. , Eisenga Michele F. , Nijkamp Maarten W. , Hoogwater Frederik J. H. , Klaase Joost M. 
Published: July 2023

Abstract
Background
Preoperative anemia is a frequent complication in pancreatic surgical patients, and it adversely affects morbidity, mortality, and postoperative red blood cell (RBC) transfusion rates. Iron deficiency (ID) is often the underlying cause of anemia and constitutes a modifiable risk factor.

Methods
Single-center, longitudinal prospective cohort study conducted between May 2019 and August 2022 at the University Medical Center Groningen in the Netherlands. Patients scheduled for pancreatic surgery were referred to the outpatient prehabilitation clinic for preoperative optimization of patient-related risk factors. Patients were screened for anemia (< 12.0 g/dL in women and < 13.0 g/dL in men) and ID (either absolute [ferritin < 30 µg/L] or functional [ferritin ≥ 30 µg/L + transferrin saturation < 20% + C-reactive protein > 5 mg/L]). Intravenous iron supplementation (IVIS) (1,000 mg ferric carboxymaltose) was administered to patients with ID at the discretion of the consulting internist. Pre- and postoperative hemoglobin (Hb) levels were assessed, and perioperative outcomes were compared between patients receiving IVIS (IVIS-group) or standard care (SC-group).

Results
From 164 screened patients, preoperative anemia was observed in 55 (33.5%) patients, and in 23 (41.8%) of these patients, ID was the underlying cause. In 21 patients, ID was present without concomitant anemia. Preoperative IVIS was administered to 25 patients, out of 44 patients with ID. Initial differences in mean Hb levels (g/dL) between the IVIS-group and SC-group at the outpatient clinic and one day prior to surgery (10.8 versus 13.2, p < 0.001, and 11.8 versus 13.4, p < 0.001, respectively) did not exist at discharge (10.6 versus 11.1, p = 0.13). Preoperative IVIS led to a significant increase in mean Hb levels (from 10.8 to 11.8, p = 0.03). Fewer SSI were observed in the IVIS-group (4% versus 25.9% in the SC-group, p = 0.02), which remained significant in multivariable regression analysis (OR 7.01 (1.68 – 49.75), p = 0.02).

Conclusion
ID is prevalent in patients scheduled for pancreatic surgery and is amendable to preoperative correction. Preoperative IVIS increased Hb levels effectively and reduced postoperative SSI. Screening and correction of ID is an important element of preoperative care and should be a standard item in daily prehabilitation practice.
Dietary inflammatory index (DII) is correlated with the incidence of non-alcoholic fatty liver disease (NAFLD): Fasa PERSIAN cohort study
Authors: Valibeygi Adib , Davoodi Ali , Dehghan Azizallah , Vahid Farhad , Hébert James R. , Farjam Mojtaba , Homayounfar Reza 
Published: July 2023

Abstract
Background
Non-alcoholic fatty liver disease (NAFLD) is a prevalent liver disease predisposing patients to life-threatening conditions, including cirrhosis. There is evidence that the incidence of NAFLD is related to the individuals’ dietary patterns; however, it is still remaining unknown whether the inflammatory potential of various foods/dietary patterns can directly predict a higher incidence of NAFLD.

Methods
In this cross-sectional cohort study, we investigated the relationship between the inflammatory potential of various food items and the incidence/odds of NAFLD. We used data from Fasa PERSIAN Cohort Study comprising 10,035 individuals. To measure the inflammatory potential of diet, we used the dietary inflammatory index (DII®). Fatty liver index (FLI) was also calculated for each individual to identify the presence of NAFLD (cut-off = 60).

Results
Our findings showed that higher DII is significantly associated with increased incidence/odds of NAFLD (OR = 1.254, 95% CI: 1.178—1.334). Additionally, we found out that higher age, female gender, diabetes mellitus, hypertriglyceridemia, hypercholesterolemia, and hypertension are other predictors of developing NAFLD.

Conclusions
It can be concluded that consuming foods with a higher inflammatory potential is associated with a greater risk of developing NAFLD. Additionally, metabolic diseases, including dyslipidemia, diabetes mellitus, and hypertension, can also predict the incidence of NAFLD.
Alternative Reimbursement Models for Health Providers in High-Performance Sport: Stakeholder Experiences and Perceptions
Authors: Carter Hannah E. , Allen Michelle J. , Toohey Liam A. , McPhail Steven M. , Drew Michael K. 
Published: July 2023

Abstract
Background
Value-based healthcare provider reimbursement models have been proposed as an alternative to traditional fee-for-service arrangements that can align financial reimbursement more closely to the outcomes of value to patients and society. This study aimed to investigate stakeholder perceptions and experiences of different reimbursement systems for healthcare providers in high-performance sport, with a focus on fee-for-service versus salaried provider models.

Methods
Three in-depth semi-structured focus group discussions and one individual interview were conducted with key stakeholders across the Australian high-performance sport system. Participants included healthcare providers, health managers, sports managers and executive personnel. An interview guide was developed using the Exploration, Preparation, Implementation, Sustainment framework, with key themes deductively mapped to the innovation, inner context and outer context domains. A total of 16 stakeholders participated in a focus group discussion or interview.

Results
Participants identified several key advantages of salaried provider models over fee-for-service arrangements, including: the potential for more proactive and preventive models of care; enhanced inter-disciplinary collaboration; and the ability for providers to have a deeper understanding of context and how their role aligns with a broader set of priorities for an athlete and the organisation. Noted challenges of salaried provider models included the potential for providers to revert to reactive care delivery when not afforded adequate capacity to provide services, and difficulties for providers in demonstrating and quantifying the value of their work.

Conclusions
Our findings suggest that high-performance sporting organisations seeking to improve primary prevention and multidisciplinary care should consider salaried provider arrangements. Further research to confirm these findings using prospective, experimental study designs remains a priority.
A comparative analysis of the skilled use of automated feedback tools through the lens of teacher feedback literacy
Authors: Buckingham Shum Simon , Lim Lisa-Angelique , Boud David , Bearman Margaret , Dawson Phillip 
Published: July 2023

AbstractEffective learning depends on effective feedback, which in turn requires a set of skills, dispositions and practices on the part of both students and teachers which have been termed feedback literacy. A previously published teacher feedback literacy competency framework has identified what is needed by teachers to implement feedback well. While this framework refers in broad terms to the potential uses of educational technologies, it does not examine in detail the new possibilities of automated feedback (AF) tools, especially those that are open by offering varying degrees of transparency and control to teachers. Using analytics and artificial intelligence, open AF tools permit automated processing and feedback with a speed, precision and scale that exceeds that of humans. This raises important questions about how human and machine feedback can be combined optimally and what is now required of teachers to use such tools skillfully. The paper addresses two research questions: Which teacher feedback competencies are necessary for the skilled use of open AF tools? and What does the skilled use of open AF tools add to our conceptions of teacher feedback competencies? We conduct an analysis of published evidence concerning teachers’ use of open AF tools through the lens of teacher feedback literacy, which produces summary matrices revealing relative strengths and weaknesses in the literature, and the relevance of the feedback literacy framework. We conclude firstly, that when used effectively, open AF tools exercise a range of teacher feedback competencies. The paper thus offers a detailed account of the nature of teachers’ feedback literacy practices within this context. Secondly, this analysis reveals gaps in the literature, signalling opportunities for future work. Thirdly, we propose several examples of automated feedback literacy, that is, distinctive teacher competencies linked to the skilled use of open AF tools.
Scarcity in abundance? Spatial inequalities in Rheumatoid Arthritis in a health system with financial equity
Authors: Maldonado Norman , Camacho Sandra , Prada Sergio I. , Hormaza-Jaramillo Andrés , Soto Victoria , García William , Paredes Nelcy , Cardona Fabián 
Published: July 2023

Abstract
Background
This paper estimates spatial inequalities of Rheumatoid Arthritis (RA) in Colombia and explores correlates of those disparities from a health system perspective.

Methods
We apply descriptive epidemiology to healthcare administrative records for estimation of crude and age-standardized prevalences, and health systems thinking for identification of barriers to effective access in RA diagnosis.

Results
The crude and age-standardized RA prevalence for Colombia in 2018 is estimated at 0.43% and 0.36%, respectively. In the contributory regime, the binding constraint is effective access to rheumatologists in rural and sparsely populated areas; this constraint in workforce affects service delivery, and ultimately comes from the lack of a differentiated model for effective provision of healthcare in those areas (governance).

Conclusions
There are opportunities for implementation of public health policies and health system interventions that would lead to a better identification of RA patients and the subsequent more precise estimation of RA prevalence, and most importantly, to reduce exposition to risk factors and accurate diagnosis and treatment of RA patients.
Impact of the Mean Cochlear Biologically Effective Dose on Hearing Preservation After Stereotactic Radiosurgery for Vestibular Schwannoma: A Retrospective Longitudinal Analysis
Authors: Tuleasca Constantin , Toma-Dasu Iuliana , Duroux Sebastien , George Mercy , Maire Raphael , Daniel Roy Thomas , Patin David , Schiappacasse Luis , Dasu Alexandru , Faouzi Mohamed , Levivier Marc 
Published: July 2023

BACKGROUND AND OBJECTIVES:
Stereotactic radiosurgery (SRS) is a useful alternative for small- to medium-sized vestibular schwannoma. To evaluate whether biologically effective dose (BEDGy2.47), calculated for mean (BEDGy2.47 mean) and maximal (BEDGy2.47 max) cochlear dose, is relevant for hearing preservation.

METHODS:
This is a retrospective longitudinal single-center study. Were analyzed 213 patients with useful baseline hearing. Risk of hearing decline was assessed for Gardner–Robertson classes and pure tone average (PTA) loss. The mean follow-up period was 39 months (median 36, 6-84).

RESULTS:
Hearing decline (Gardner–Robertson class) 3 years after SRS was associated with higher cochlear BEDGy2.47 mean (odds ratio [OR] 1.39, P = .009). Moreover, BEDGy2.47 mean was more relevant as compared with BEDGy2.47 max (OR 1.13, P = .04). Risk of PTA loss (continuous outcome, follow-up minus baseline) was significantly corelated with BEDGy2.47 mean at 24 (beta coefficient 1.55, P = .002) and 36 (beta coefficient 2.01, P = .004) months after SRS. Risk of PTA loss (>20 dB vs ≤) was associated with higher BEDGy2.47 mean at 6 (OR 1.36, P = .002), 12 (OR 1.36, P = .007), and 36 (OR 1.37, P = .02) months. Risk of hearing decline at 36 months for the BEDGy2.47 mean of 7–8, 10, and 12 Gy2.47 was 28%, 57%, and 85%, respectively.

CONCLUSION:
Cochlear BEDGy2.47 mean is relevant for hearing decline after SRS and more relevant as compared with BEDGy2.47 max. Three years after SRS, this was sustained for all hearing decline evaluation modalities. Our data suggest the BEDGy2.47 mean cut-off of ≤8 Gy2.47 for better hearing preservation rates.
Pakistan National Guidelines for Pediatric High-Grade Gliomas
Authors: Bashir Farrah , Qureshi Bilal Mazhar , Minhas Khurram , Tabori Uri , Bouffet Eric , Hawkins Cynthia , Enam Ather , Mushtaq Naureen 
Published: July 2023

Pediatric high-grade glioma (pHGG) is highly malignant central nervous system tumor and constitute 10% of the pediatric gliomas. Effective treatment needs a functioning multi-disciplinary team including pediatric neuro oncologist, neurosurgeon, neuroradiologist, neuropathologist and radiation oncologist. Despite surgical resection, radiotherapy and chemotherapy, most HGG will recur resulting in early death. A significant proportion of HGG occurs in context of cancer predisposition syndromes like Constitutional Mismatch Repair Deficiency (CMMRD) also known as Biallelic Mismatch Repair Deficiency (bMMRD) characterized by high mutational burden. The incidence of HGG with CMMRD is one per million patients. bMMRD is caused by homozygous germline mutations in one of the four Mis Match Repair (MMR) genes (PMS2, MLH1, MSH2, and MSH6). The use of TMZ is now avoided in CMMRD related HGG due to its limited response and known ability to increase the accumulation of somatic mutations in these patients, increasing the risk of secondary tumors. HGG should be managed under the care of multidisciplinary team to receive optimum treatment. This is particularly important for low middle-income countries (LMIC) with limited resources like Pakistan.
doi: https://doi.org/10.12669/pjms.39.5.6300
How to cite this: Bashir F, Qureshi BM, Minhas K, Tabori U, Bouffet E, Hawkins C, et al. Pakistan National Guidelines for Pediatric High-Grade Gliomas. Pak J Med Sci. 2023;39(5):---------. doi: https://doi.org/10.12669/pjms.39.5.6300
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Comparative evaulation of condylar guidance obtained by digital panoramic radiographic images with that of obtained during jaw relation and try-in using two different interocclusal record material in completely edentulous patients: an in vivo study
Authors: Doshi Khushbu , Sathe Seema 
Published: July 2023

Background: In completely edentulous patients, maintaining the patient's TMJ health and intraoral components is very important. This can be achieved by an accurate interocclusal record, which can we taken by various materials and also at various stages. Simulation of the temparomandibular joint anatomy and mandibular movements is possible on a semi adjustable articulator which is use widely in prosthodontics. Transferring the record on articulator is a critical step in fabrication of complete dentures so it should be done precisely to reduce chair side time and also to avoid complications for patients. This study examines which material is more accurate and also records which stage gives more precision, by comparing the Condylar guidance on radiographs. This is because it has consistent bony landmarks and is comparable to clinical methods in terms of standardisation. The objective will be to determine the inter occlusal records created during Jaw Relation stage and Try-in using reinforced wax and Polyvinyl siloxane and compare these values to the condylar guidance obtained by OPG. Methods: Recording the Condylar Guidance value on OPG, obtained with tracing Glenoid fossa, Articular eminence and the Frankfurt Horizontal Plane. Followed with conventional steps in making complete dentures, at jaw relation and try-in stage. we will record values of condylar guidance with the two different Interocclusal record materials. Expected result: It will help the clinicians to get knowledge about obtaining precise condylar inclination angle by using right interocclusal record materials. Conclusions: This study will help us to obtain condylar inclination which inturn helps the patients satisfaction as it maintains the patient's TMJ health and intraoral components.
Effectiveness of pelvis and trunk stabilization exercises over conventional physiotherapy to improve dynamic trunk balance in cerebellar ataxia: a randomized controlled trial
Authors: Sasun Anam , Qureshi Mohammad Irshad , Raghuveer Raghumahanti , Harjpal Pallavi 
Published: July 2023

Cerebellar ataxia is caused by several hereditary or acquired aetiologies that eventually lead to abnormalities in the cerebellum. Patients with cerebellar ataxia may experience balance issues, eye movement abnormalities, limb incoordination, gait instability, and speech impairment as a result. The available treatment options for cerebellar ataxia are rather limited, causing many patients to struggle with daily activities. Although the success rate of a range of therapeutic interventions has been determined, evidence-based exercise guidelines for the treatment of balance disorders and associated problems in people with cerebellar ataxia are currently unavailable. Thus, physiotherapists must explore novel approaches to successfully manage the symptoms of ataxia and further improve the quality of life of patients. The current study protocol will provide new insight as no article available to date has looked at trunk and pelvis stabilization exercise programme as an intervention for treating cerebellar ataxia. We hereby propose a study, which aims to investigate the impact of conventional exercises and trunk and pelvis stabilization exercises along with conventional exercises on subjects with Cerebellar ataxia in a two-arm randomized controlled trial on improving SARA, TIS, BBS, Barthel Index, WHOQOL The total participants will be divided into two-arm parallel groups and the intervention will be given for complete 6 weeks, 5 days in a week. The outcome measure will be evaluated at baseline and the end of 6 weeks. The results will be evaluated after 6 weeks. If the hypothesis of our study proves to be effective, then this physiotherapy intervention could be included in the management of cerebellar ataxia
Genome sequence for the thick topshell, Phorcus lineatus (da Costa, 1778)
Authors: Mieszkowska Nova , Mrowicki Rob ,   Marine Biological Association Genome Acquisition Lab,   Darwin Tree of Life Barcoding collective,   Wellcome Sanger Institute Tree of Life programme,   Wellcome Sanger Institute Scientific Operations: DNA Pipelines collective,   Tree of Life Core Informatics collective,   Darwin Tree of Life Consortium
Published: July 2023

We present a genome assembly from an individual Phorcus lineatus (the thick topshell; Mollusca; Gastropoda; Trochida; Trochidae). The genome sequence is 958 megabases in span. Most of the assembly (99.9%) is scaffolded into 18 chromosomal pseudomolecules. The mitochondrial genome has also been assembled and is 19.1 kilobases in length.
História, resistências e conexões no agrário mexicano: da globalização da agricultura à formação do EZLN
Authors: Da Silva Émerson Neves 
Published: July 2023

O presente trabalho analisa a conexão histórica do estabelecimento do Exército Zapatista de Libertação Nacional (EZLN) com o processo de globalização da agricultura no México. A inserção dependente no capitalismo global provocou profundas mudanças tecnológicas e a submissão da agricultura mexicana ao capital financeiro e industrial. Nesse contexto é gestado historicamente o EZLN. A análise utiliza a abordagem teórica da história global para compreender a interação dialética dos sujeitos sociais com a modernização capitalista da agricultura. O movimento é compreendido enquanto uma experiência de resistência social no território latino-americano, constituída a partir da dialética do conflito, ou seja, da capacidade dos atores sociais mobilizarem saberes populares e científicos no processo de luta social ao enfrentamento das contradições econômicas, sociais e políticas originadas pela globalização da agricultura. Nesse fazer histórico, os zapatistas produziram a identidade coletiva e o ideário do grupo.
Legar ao além: uma análise das propriedades da Santa Casa de Misericórdia do Rio de Janeiro
Authors: Machado Karoline Marques 
Published: July 2023

O presente artigo visa compreender a relação entre a Irmandade de Nossa Senhora da Misericórdia, como receptora de legados pios, e o imaginário da salvação das almas que possibilitou o acúmulo de bens imóveis pelos irmãos de caridade. As propriedades recebidas pela Misericórdia foram, em sua maioria, amealhadas através de doações estipuladas em testamento por indivíduos que almejavam alcançar o Paraíso. A Misericórdia recebeu o privilégio de manter sob o seu controle alguns dos bens de raiz doados por homens e mulheres que buscavam a remissão dos pecados ao buscarem a salvação eterna. A correlação entre salvação e caridade representa um caminho para entender o papel da Misericórdia e, principalmente, como a Irmandade virou uma das principais detentoras de terras urbanas no Rio de Janeiro durante o período colonial.
Bedeutung und Management von Cloud Computing, Multi-Cloud und Cloud Brokerage in Unternehmen
Authors: Günther Jochen , Praeg Claus-Peter 
Published: July 2023

ZusammenfassungCloud Computing hat sich in den letzten Jahren dynamisch entwickelt. Eine Vielzahl von Unternehmen nutzen Cloud-basierte Lösungen für verschiedenste Anwendungszwecke. Die Virtualisierung und Zusammenlegung von IT-Ressourcen wie Speicher, Anwendungen und Servern verbessert die Flexibilität und Verfügbarkeit von IT-Services. Dies ermöglicht eine schnellere und hochverfügbare Bereitstellung von digitalen Diensten und Anwendungen sowie eine einfache gemeinsame Nutzung von IT-Innovationen. Der Beitrag hebt die Vorteile des Cloud Computing hervor, darunter schnelle Elastizität, messbarer Service, Ressourcenpooling und Selbstbedienung auf Abruf. Allerdings kann Cloud Computing zu höheren Kosten führen, insbesondere bei datenintensiven Anwendungen. Darüber hinaus müssen Cloud-Services in das IT-Service-Management eines Unternehmens integriert werden, um unbeabsichtigte Schatten-IT zu vermeiden und die zunehmende Komplexität bei der Verwaltung externer Service-Provider zu kontrollieren. Etablierte Frameworks für das IT-Service-Management, wie ITIL und COBIT, bieten Referenzprozesse und Managementpraktiken für wertorientierte Ansätze. Der Beitrag empfiehlt Unternehmen, ihre Multi-Cloud-Strategie und -Richtlinien zu definieren, die Auswahl von Cloud-Anbietern anhand von geschäftlichen und technischen Kriterien zu priorisieren.