bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of Genetic Variability, Correlation and Path for Yield and Its Attributing Traits in Wheat (Triticum aestivum L.)
Authors: Meherbabu Atluri , Kumar V. S. Varun , Janeja Harmeet Singh , Talekar Nilesh , Sandal Sanjeet Singh 
Published: June 2023

The current study was undertaken to analyze the genetic variability, correlation and path for yield and its attributing traits at agriculture research farm, Department of Genetics and Plant Breeding, School of Agriculture, Lovely Professional University, Punjab during during Rabi 2021-22 and 2022-23. Augmented design with F2 seeds planted in ear to row fashion in 4 rows were used to study variability, correlation and path including 2 parent and its 6 F2’s for the 9 traits viz. plant height, spike length, number of tillers per plant, number of spikes per plant, number of spikelets per ear, number of grains per ear, biological yield, harvest index and grain yield. Finding revealed that grain yield revealed positive and highly significant correlation with number of tillers per plant (rp= 0.8387, rg= 0.8709) and biological yield (rp= 0.9671, rg= 0.9965) while positive and significant correlation with Number of spikes per plant (rp= 0.7168, rg= 0.7253) at both phenotypic and genotypic level. Biological yield per plant revealed highest positive direct effect (1.0642, 0.8700) with significant association with grain yield (0.9965, 0.9671) whereas Number of tillers reveals least positive direct effect on grain yield (0.0183, 0.0834) at both genotypic and phenotypic level. PCV was higher than GCV for all the traits indicated an influence of environment over the traits. Number of spikelets per ear recorded highest PCV and GCV followed by Grain yield. Heritability (h2b) found higher for grain yield (84.2) followed by Number of spikelets per ear (83.4), Number of Grains per ear (82.7) and Plant height (80.1). Genetic advance (GA) recorded higher Number of spikelets per ear (35.07) followed by Grain yield (11.93). Moderate GA recorded for Plant Height (7.67) and Biological yield (6.88) whereas Spike length (0.62) recorded lowest GA. Hence, selection for these mentioned characters could bring improvement in yield and yield components.
Tea Quality and Value-Added Marketing Potential of Safe and Sustainable Tea in Indian Domestic Market: Consumers Choice for Conventional vis-a-vis Sustainable Tea
Authors: Bhattacharyya S. , Bera R. , Seal A. 
Published: June 2023

Now a days consumers are more intended to sustainable products. Especially when it is promoted as health drink, its quality and sustainable background specially the environment in which it is produced have special significance for present day consumers. This study was done to assess whether sustainable initiative in tea and value added marketing can impact the consumer behavioural pattern w.r.t. selection of sustainable product over their conventional counterpart. The study showed that, adoption of Inhana Rational Farming Technology towards safe and sustainable tea initiatives called ‘Clean Tea Program’ has influenced tea quality specially polyphenols which have specific health relevance. On the other hand, study of value added marketing potential of safe and sustainable tea in Indian domestic market was done among people representing diversity of our social cluster in terms of age, education, professions and income. However irrespective of this variability, most people prefer ecofriendly products whereas pricing of the sustainable tea also plays a major crucial factor for final decision-making process. Education and age group have also significant influence on decision making process and at the same time different other factors viz environmental concern, health aspects, effect of electronic and social media, promotional activities and marketing offers influence consumers towards their purchasing decision. Finally it may be concluded that sustainable initiatives along with value added marketing and maintaining a competitive price range can influencing consumer’ choice. And to make the product more competitive, it will be essential to develop it under a sustainable environment and without increasing the cost of production.
Comparing Risk for Second Primary Cancers After Intensity-Modulated vs 3-Dimensional Conformal Radiation Therapy for Prostate Cancer, 2002-2015
Authors: Pithadia Kishan J. , Advani Pragati G. , Citrin Deborah E. , Bekelman Justin E. , Withrow Diana R. , Berrington de Gonzalez Amy , Morton Lindsay M. , Schonfeld Sara J. 
Published: June 2023

ImportanceCompared with 3-dimensional conformal radiotherapy (3DCRT), intensity-modulated radiotherapy (IMRT) can spare nearby tissue but may result in increased scatter radiation to distant normal tissue, including red bone marrow. It is unclear whether second primary cancer risk varies by radiotherapy type.ObjectiveTo evaluate whether radiotherapy type (IMRT vs 3DCRT) is associated with second primary cancer risk among older men treated for prostate cancer.Design, Setting, and ParticipantsIn this retrospective cohort study of a linked database of Medicare claims and Surveillance, Epidemiology, and End Results (SEER) Program population-based cancer registries (2002-2015), male patients aged 66 to 84 diagnosed with a first primary nonmetastatic prostate cancer from 2002 to 2013, as reported to SEER, and who received radiotherapy (IMRT and/or 3DCRT without proton therapy) within the first year following prostate cancer were identified. The data were analyzed from January 2022 through June 2022.ExposureReceipt of IMRT and 3DCRT, based on Medicare claims.Main Outcomes and MeasuresThe association between radiotherapy type and development of a subsequent hematologic cancer at least 2 years after prostate cancer diagnosis or a subsequent solid cancer at least 5 years after prostate cancer diagnosis. Hazard ratios (HRs) and 95% CIs were estimated using multivariable Cox proportional regression.ResultsThe study included 65 235 2-year first primary prostate cancer survivors (median [range] age, 72 [66-82] years; 82.2% White patients) and 45 811 5-year survivors with similar demographic characteristics (median [range] age, 72 [66-79] years; 82.4% White patients). Among 2-year prostate cancer survivors (median [range] follow-up, 4.6 [0.003-12.0] years), 1107 second hematologic cancers were diagnosed (IMRT, 603; 3DCRT, 504). Radiotherapy type was not associated with second hematologic cancers overall or any specific types evaluated. Among 5-year survivors (median [range] follow-up, 3.1 [0.003-9.0] years), 2688 men were diagnosed with a second primary solid cancer (IMRT, 1306; 3DCRT, 1382). The overall HR for IMRT vs 3DCRT was 0.91 (95% CI, 0.83-0.99). This inverse association was restricted to the earlier calendar year period of prostate cancer diagnosis (HR2002-2005 = 0.85; 95% CI, 0.76-0.94; HR2006-2010 = 1.14; 95% CI, 0.96-1.36), with a similar pattern observed for colon cancer (HR2002-2005 = 0.66; 95% CI, 0.46-0.94; HR2006-2010 = 1.06; 95% CI, 0.59-1.88).Conclusions and RelevanceThe results of this large, population-based cohort study suggest that IMRT for prostate cancer is not associated with an increased risk of second primary cancers, either solid or hematologic, and any inverse associations may be associated with calendar year of treatment.
Acceptance and transformation of the housing “ladder” in slum resettlement projects in Colombo, Sri Lanka
Authors: Maeda Masahiro 
Published: June 2023

AbstractThis study focuses on the Sustainable Township Development Programme, a slum resettlement project that represents a recent housing policy shift in Sri Lanka. Through the actual housing improvement activities of the residents of Sahaspura, a resettlement housing complex, and the slum residents in the surrounding area, the response of the beneficiaries to the housing “ladder” was clarified. Policy makers and planners intended to merge slum dwellers into the formal housing market through the provision of “ladders,” a set of regular ownership and dwelling units in Sahaspura. However, residents have responded in a variety of ways, including house extensions and renovations and informal housing transactions according to their daily needs. As a result, the original intention of the planners was distorted and the “ladder” was incorporated into the indigenous housing market in the slum, revealing a “transformation” from legal tenure to de facto tenure. Factors contributing to this transformation include the location of resettlement sites near urban areas, the looseness of housing environment management, the possibility of choosing the multiple form of tenure, and the existence of actors and social relations that guarantee access to land.
Unbiased recursive least squares identification methods for a class of nonlinear systems with irregularly missing data
Authors: Liu Wenxuan , Li Meihang 
Published: June 2023

SummaryMissing data often occur in industrial processes. In order to solve this problem, an auxiliary model and a particle filter are adopted to estimate the missing outputs, and two unbiased parameter estimation methods are developed for a class of nonlinear systems (e.g., bilinear systems) with irregularly missing data. Firstly, an auxiliary model is constructed to estimate the unknown output, and an auxiliary model‐based multi‐innovation recursive least squares algorithm is presented by expanding the scalar innovation to an innovation vector. Secondly, according to the bias compensation principle, an auxiliary model‐based bias compensation multi‐innovation recursive least squares algorithm is proposed to compensate the bias caused by the colored noise. Thirdly, for further improving the parameter estimation accuracy, the unknown true output is estimated by a particle filter, and a particle filtering‐based bias compensation multi‐innovation recursive least squares algorithm is developed. Finally, a numerical example is selected to validate the effectiveness of the proposed algorithms. The simulation results indicate that the proposed algorithms have good performance in identifying bilinear systems with irregularly missing data.
Precision X‐Ray Time‐Lapse Flexible Imaging from Fluoride Nanocrystals with the Constructed Deep Traps
Authors: Peng Songcheng , Chen Luwei , Lu Lan , Zhang Peng , Wen Hongyu , Yan Shuangpeng , Wang Wei , Xiong Yuanyuan , Lu JinKang , Qiu Jianbei , Yu Jie , Yu Xue , Xu Xuhui 
Published: June 2023

AbstractX‐ray time‐lapse imaging allows for precise radiographic imaging of the item after X‐ray has been terminated, which is important for simplifying legacy X‐ray detectors and avoiding health hazards caused by ionizing radiation during the imaging process. However, the premature discharge of carriers from shallow traps at room temperature over time leads to the loss of imaging information, making an accurate representation of the recorded information to achieve accurate time‐lapse imaging still a challenge. Here, it is demonstrated that monodispersed NaLuF4: Tb3+ nanocrystals with the replacement of Na+ by Cs+ ions in the lattice matrix realize a superior X‐ray time‐lapse imaging. It is found that the incorporation of Cs+ ions amplifies the deep trap storage capacity, which ensures the stable presence of carriers under thermal perturbation at room temperature. Imaging information with a spatial resolution of 12.0 lp mm−1 can be accurately represented even after the irradiation of the X‐ray has been terminated for 192 h. X‐ray time‐lapse imaging not only allows accurate reading of long‐term stored imaging information but also endows the visualization of X‐ray imaging independent of the dangerous radiation, which will offer great opportunities for X‐ray inspection on a larger scale.
High‐Speed Broadband Hybrid Perovskite Nanocrystals /Ge Photodetector from UV to NIR
Authors: Yang Yazhou , Liu Xiangquan , Liu Taoran , Chen Dan , Ye Zhenglan , Li Jiayi , Huang Qinxing , Zhu Yupeng , Pang Yaqing , Zhang Diandian , Liu Zhi , Cheng Buwen , Zheng Jun , Zuo Yuhua 
Published: June 2023

AbstractHigh speed broadband photodetectors (PDs) have attracted significant interest for many applications such as imaging, gas sensing, and night vision. In this study, the widest reported detection range is achieved from 254 nm to 1800 nm by integrating CsPb(BrCl)3: Yb3+ nanocrystals (NCs) with Germanium (Ge) on a Si substrate. To overcome the persistent photoconductance (PPC) effect that limits the detector response speed in the UV region, this study proposes a down conversion technology to convert UV light to 980 nm infrared light by applying a CsPb(BrCl)3: Yb3+ NCs. The response time of the hybrid PD at 275 nm decreased significantly from several hundred seconds to 1.21 µs. Moreover, benefiting from the CsPb(BrCl)3: Yb3+ NCs antireflection layer, the responsivity of a hybrid CsPb(BrCl)3: Yb3+ NCs /Ge metal semiconductor metal (MSM) PD has enhanced the whole detection band, especially at 1310 nm, which increased by 80% from 0.16 to 0.29 A W−1. This work promotes the development of perovskite integrated optoelectronic devices and provides a feasible route for broad‐band PD from the UV to near infrared (NIR) band.
Modulation of Autophagy Direction to Enhance Antitumor Effect of Endoplasmic‐Reticulum‐Targeted Therapy: Left or Right?
Authors: Shen Xinran , Deng Yudi , Chen Liqiang , Liu Chendong , Li Lian , Huang Yuan 
Published: June 2023

AbstractStrategies that induce dysfunction in the endoplasmic reticulum (ER) hold great promise for anticancer therapy, but remain unsatisfactory due to the compensatory autophagy induction after ER disruption. Moreover, as autophagy can either promote or suppress cell survival, which direction of autophagy better suits ER‐targeting therapy remains controversial. Here, a targeted nanosystem is constructed, which efficiently escorts anticancer therapeutics into the ER, triggering substantial ER stress and autophagy. Concurrently, an autophagy enhancer or inhibitor is combined into the same nanoparticle, and their impacts on ER‐related activities are compared. In the orthotopic breast cancer mouse model, the autophagy enhancer increases the antimetastasis effect of ER‐targeting therapy and suppresses over 90% of cancer metastasis, while the autophagy inhibitor has a bare effect. Mechanism studies reveal that further enhancing autophagy accelerates central protein snail family transcriptional repressor 1 (SNAI1) degradation, suppressing downstream epithelial–mesenchymal transition, while inhibiting autophagy does the opposite. With the same trend, ER‐targeting therapy combined with an autophagy enhancer provokes stronger immune response and tumor inhibition than the autophagy inhibitor. Mechanism studies reveal that the autophagy enhancer elevates Ca2+ release from the ER and functions as a cascade amplifier of ER dysfunction, which accelerates Ca2+ release, resulting in immunogenic cell death (ICD) induction and eventually triggering immune responses. Together, ER‐targeting therapy benefits from the autophagy‐enhancing strategy more than the autophagy‐inhibiting strategy for antitumor and antimetastasis treatment.
Synergistic Effect of Crown Ether and Main‐Chain Engineering for Boosting Hydrogen Evolution of Polymer Photocatalysts in Seawater
Authors: Chang Chih‐Li , Huang Tse‐Fu , Lin Wei‐Cheng , Ting Li‐Yu , Shih Chin‐Hsuan , Chen Yan‐Heng , Liu Jia‐Jen , Lin Yu‐Tung , Tseng Yuang‐Ting , Wu Yi‐Hsiang , Sun Yu‐En , Elsayed Mohamed Hammad , Chen Chin‐Wen , Yu Chi‐Hua , Chou Ho‐Hsiu 
Published: June 2023

AbstractPhotocatalytic hydrogen evolution from natural seawater faces the severe challenges of abundant salts, which adsorb on the active sites and result in undesirable side reactions and photocatalyst poisoning. Herein, a series of main‐chain‐engineered discontinuously conjugated polymer (DCP) photocatalysts is presented with bifunctional crown ether (CE) structures for hydrogen evolution from seawater. The hydrophilic CE can significantly inhibit the aggregation of DCPs induced by salts. Meanwhile, cyclic CE can effectively adsorb cations to uncover the active sites to increase their interaction with protons, which can increase the hydrogen evolution rates and significantly reduce the efficiency roll‐off in natural seawater. Through atomistic studies, the formation of hydrogen bonds with bifunctional CE is elucidated and further analysis of the microscale mechanisms is also conducted using molecular dynamics and ab initio techniques. This work suggests that CE‐based polymer has the potential to enhance its ability to produce hydrogen through photocatalysis using seawater.
Design of a rainfall simulator for classroom demonstration and field research
Authors: Jaqueth Aubrey L. , Marshall Melanie M. , Ciampaglio Chuck N. 
Published: June 2023

AbstractRainfall is a key abiotic factor of ecosystems that can both provide benefits and contribute to negative environmental impacts. Due to spring precipitation levels increasing in the Midwest, there has been increased interest in developing and evaluating practices that can mitigate the effects of heavy rainfall. As this is an area of interest for both agriculture and environmental sciences, demonstrating the actions of severe rainfall can be a powerful tool in the natural sciences classroom as well as in the field. Rainfall simulators are ideal for this demonstration as they can create repeated, uniform rainfall events while introducing limited variability between events. Building on previous literature, we constructed a cost‐effective, easily transportable design that can be utilized in the classroom, the lab, and the field. Here, tests were conducted to measure flow rate, rain droplet size, and uniformity of water dispersion on the cost‐effective and easily obtained solid cone‐style herbicide nozzle. We found no statistically significant differences among rainfall dispersion metrics or in raindrop uniformity analyses. This demonstrates the capability of constructing this type of teaching and research equipment at little cost while producing highly consistent and size‐relevant artificial rainfall.
The examination of Kraepelin's diagnoses of dementia praecox and manic‐depressive insanity in pedigrees: Studies of Schuppius in 1912 and Wittermann in 1913
Authors: Kendler Kenneth S. , Klee Astrid 
Published: June 2023

AbstractIn the first two decades of the 20th century, a new approach to psychiatric genetics research emerged in Germany from three roots: (i) the wide‐spread acceptance of Kraepelin's diagnostic system, (ii) increasing interest in pedigree research, and (iii) excitement about Mendelian models. We review two relevant papers, reporting analyses of, respectively, 62 and 81 pedigrees: S. Schuppius in 1912 and E. Wittermann in 1913. While most prior asylum based studies only reported a patient's “hereditary burden,” they examined diagnoses of individual relatives at a particular place in a pedigree. Both authors focused on the segregation of dementia praecox (DP) and manic‐depressive insanity (MDI). Schuppius reported that the two disorders frequently co‐occurred in his pedigrees while Wittermann found them to be largely independent. Schuppius was skeptical of the feasibility of evaluating Mendelian models in humans. Wittermann, by contrast, with advice from Wilhelm Weinberg, applied algebraic models with proband correction to DP in his sibships with results consistent with autosomal recessive transmission. While he had less data, Wittermann suggested that MDI was likely an autosomal dominant disorder. Both authors were interested in other disorders or traits appearing in pedigrees dense with DP (e.g., idiocy) or MDI (e.g., highly excitable individuals).
Autosomal dominant genodermatoses in adults being heralded by superimposed skin lesions in children
Authors: Happle Rudolf 
Published: June 2023

AbstractIn autosomal dominant skin disorders, pronounced mosaic involvement may sometimes occur in the neonate, originating in a heterozygous embryo from early loss of heterozygosity, probably during the first week after fertilization. In biallelic phenotypes, such overlaying mosaic involvement may coexist with disseminated mosaicism, for example, in neurofibromatosis or tuberous sclerosis. In other phenotypes, however, classical nonsegmental involvement tends to appear much later, which is why the superimposed mosaic is a heralding feature. In Brooke–Spiegler syndrome (eccrine cylindromatosis), a large pedigree documented a 5‐year‐old boy with multiple, congenital small eccrine cylindromas along the lines of Blaschko. Disseminated cylindromas were absent because they usually appear in adulthood. ̶ In Hornstein–Knickenberg syndrome, an affected woman had an 8‐year‐old son with a nevus comedonicus‐like lesion exemplifying a forerunner of the syndrome. (“Birt‐Hogg‐Dubé syndrome” represents a nonsyndromic type of hereditary perifollicular fibromas.) In glomangiomatosis, neonatal superimposed mosaicism is a heralding feature because disseminated lesions appear during puberty or adulthood. Linear porokeratosis is a harbinger of disseminated porokeratosis that develops 30 or 40 years later. ̶ Cases of superimposed linear Darier disease were forerunners of nonsegmental manifestation. ̶ In a case of Hailey–Hailey disease, neonatal mosaic lesions heralded nonsegmental involvement that began 22 years later.
Thermally Crosslinked F‐rich Polymer to Inhibit Lead Leakage for Sustainable Perovskite Solar Cells and Modules
Authors: Zhang Jiakang , Li Zhipeng , Guo Fengjuan , Jiang Haokun , Yan Wenjian , Peng Cheng , Liu Ruixin , Wang Li , Gao Hongtao , Pang Shuping , Zhou Zhongmin 
Published: June 2023

AbstractHigh‐performance perovskite solar cells have demonstrated commercial viability, but still face the risk of contamination from lead leakage and long‐term stability problems caused by defects. Here, an organic small molecule (octafluoro‐1,6‐hexanediol diacrylate) is introduced into the perovskite film to form a polymer through in situ thermal crosslinking, of which the carbonyl group anchors the uncoordinated Pb2+of perovskite and reduces the leakage of lead, along with the −CF2− hydrophobic group protecting the Pb2+from water invasion. Additionally, the polymer passivates varieties of Pb‐related and I‐related defects through coordination and hydrogen bonding interactions, regulating the crystallization of perovskite film with reduced trap density, releasing lattice strain, and promoting carrier transport and extraction. The optimal efficiencies of polymer‐incorporated devices are 24.76 % (0.09 cm2) and 20.66 % (14 cm2). More importantly, the storage stability, thermal stability, and operational stability have been significantly improved.
A Humidity‐Induced Large Electronic Conductivity Change of 107 on a Metal‐Organic Framework for Highly Sensitive Water Detection
Authors: Deng Wei‐Hua , Li Qiao‐Hong , Chen Jie , Wang Chuan‐Zhe , Fu Zhi‐Hua , Ye Xiao‐Liang , Wang Guan‐E , Xu Gang 
Published: June 2023

AbstractThe electronic conductivity (EC) of metal–organic frameworks (MOFs) is sensitive to strongly oxidizing guest molecules. Water is a relatively mild species, however, the effect of H2O on the EC of MOFs is rarely reported. We explored the effect of H2O on the EC in the MOFs (NH2)2‐MIL‐125 and its derivatives with experimental and theoretical investigations. Unexpectedly, a large EC increase of 107 on H2SO4@(NH2)2‐MIL‐125 by H2O was observed. Brønsted acid–base pairs formed with the −NH2 groups, and H2SO4 played an important role in promoting the charge transfer from H2O to the MOF. Based on H2SO4@(NH2)2‐MIL‐125, a high‐performance chemiresistive humidity sensor was developed with the highest sensitivity, broadest detection range, and lowest limit of detection amongst all reported sensing materials to date. This work not only demonstrated that H2O can remarkably influence the EC of MOFs, but it also revealed that post‐modification of the structure of MOFs could enhance the influence of the guest molecule on their EC to design high‐performance sensing materials.