bluuebunny/crossref_metadata_2025_split huggingface dataset:
HORIZONTAL CIRCULAR PUMPING WELLS TO MINIMIZE SALINE WATER UPCONING: WATER RESOURCE DEVELOPMENT MEASURE FOR TROPICAL SAVANNA CLIMATIC NINH THUAN AREA, VIETNAM
Authors: Нгуен Ван Хоанг , Тинь Хоа Ту , Шакиров Ренат Белалович , Сырбу Надежда Сергеевна , Тран Тхи Тхуи Хуонг , Ли Наталья Сергеевна 
Published: April 2023

Link for citation: Nguyen Van Hoang, Trinh Hoai Thu, Shakirov R.B., Syrbu N.S., Tran Thi Thuy Huong, Lee N.S. Horizontal circular pumping wells to minimize saline water upconing: water resource development measure for tropical savanna climatic Ninh Thuan area, Vietnam. Bulletin of the Tomsk Polytechnic University. Geo Аssets Engineering, 2023, vol. 334, no. 4, рр.209-220. In Rus.
The relevance. The Southern central region of Vietnam, including Ninh Thuan province, has a tropical savanna climate and has been heavily suffering from drought and water salinization. Ninh Thuan province has faced severe droughts in recent years because of the increase of the frequency and intensity of extreme weather conditions, the water scarcity, and the salinity of the groundwater. The distribution of fresh and saline groundwater in Ninh Thuan plain has three zones: 1) zone of entire profile with fresh groundwater; 2) zone of the upper profile's with fresh groundwater and of the lower profile's with saline groundwater, and 3) zone of entire profile with saline groundwater. The groundwater abstraction facilities in the first zone are vulnerable to salinization from surrounding saline water, while in the second zone are vulnerable to the upconing saline water from below. The aim: to determine the optimal groundwater pumping in respect to given water level drawdown, to show that the horizontal circular wells are the best for minimization of saline water upconing, to determine the relationship between the saline water upconing height and the radii of the horizontal circular wells. Objects: tropical savanna climate, coastal plain, fresh and saline groundwater, aquifer with fresh water in the upper profile and saline water in the lower profile, circular groundwater wells, saline water upconing. Methods: finite element method, dynamic programming, Dagan–Bear model of saline water upconing, superimposition principle in dealing with multiple pumping points for identification of overall saline water upconing. Results. Different schemes of pumping fields with either vertical wells or horizontal circular wells with different radii were analyzed for saline water upconing. The time of saline upconing height in all the alternative schemes were determined. A very well regression curve of the relationship between the time saline water upconing to the horizontal circular wells and the circular well radii was obtained. The analysis results are extremely useful supporting well design in terms of minimization of saline water upconing.
The impact of integrated technology on students' logical thought in mathematics: A case study of Kazakhstan
Authors: Ontuganova Shynar , Zhumabayeva Zhazira , Abilkhairova Zhanar , Akzholova Aktoty , Zhunusbekova Aziza 
Published: April 2023

This study aims to assess the impact of integrative technology on the improvement of the logical thinking of students in mathematics, their goals and the appropriate technological process. The study used mixed research methods. Participants included third-grade students attending elementary schools No. 12 and Ataturk in Kentau (Kazakhstan) during 2019-2022. The results indicated that primary school teachers do not pay attention to the improvement of the logical thinking of lower-grade students in mathematics. The research findings suggest that integrative technology improved logical thought in lower-grade students in the experimental group in mathematics. Finally, the study offers suggestions to improve the work of primary school teachers in developing the logical thinking of children in mathematics in Kazakhstan to increase the effectiveness of this process without increasing the burden on students or changing the curriculum.
CARACTERÍSTICAS DAS PESSOAS ACOMETIDAS PELA COVID-19 EM PORTO NACIONAL (29/04/2020 – 31/08/2021)
Authors: Macêdo Daniela Pereira de , Foschiera Atamis Antonio 
Published: April 2023

A pandemia é a disseminação mundial de uma doença que se espalha em vários países e que atinge mais que um continente. O Coronavírus (SARS-CoV-2), descoberto em 2019, causa infecções respiratórias, desenvolvendo a doença denominada Covid-19. O Brasil entrou em momento de tensão devido a esse vírus em março de 2020. As principais portas de entradas do Coronavírus foram os aeroportos com ligação internacional, acessados por pessoas que chegavam de diferentes países. Já presente no Brasil, o Coronavírus vai se disseminar internamente por aeroportos regionais, rodovias e hidrovias. No Tocantins a Covid-19 vai ter sua disseminação inicial por aeroportos regionais e rodovias. Porto Nacional registrou o primeiro caso de Covid-19 em 29 de abril de 2020. O presente trabalho trata de uma análise quantitativa/descritiva dos dados ocorridos em Porto Nacional desde o registro do primeiro caso de Covid-19 até 31 de agosto de 2021. Para a realização desse trabalho utilizou-se dados dos boletins epidemiológicos e de controle diário das pessoas com notificação da doença. Os dados foram obtidos junto à Vigilância Epidemiológica de Porto Nacional. As pessoas de sexo feminino foram as que mais apresentaram casos positivos de Covid-19, enquanto as do sexo masculino foram as que mais tiveram óbitos. O período de maior número de óbito se deu durante a segunda onda da doença no município. A grande maioria das pessoas hospitalizadas por Covid-19 estavam internadas em hospitais públicos.
Palavras-Chave: Geografia da Saúde; Covid-19; Porto Nacional.
Pengembangan Learning Object untuk Mata Pelajaran Ekonomi
Authors: Nurul Nabilah  , Uwes Anis Chaeruman  , Diana Ariani  
Published: May 2023

Penelitian ini bertujuan untuk menghasilkan Learning object Mata Pelajaran Ekonomi, dengan topik Keseimbangan Pasar dan Struktur Pasar untuk siswa kelas X SMA Labschool Jakarta. Prosedur pengembangan yang digunakan adalah Model Rapid Prototyping oleh Tripp & Bichelmeyer. Evaluasi Learning object dilakukan melalui expert review dan one-to-one evaluation yang melibatkan 2 ahli materi, 1 ahli desain pembelajaran, 2 ahli media, dan 2 pengguna, yang diukur berdasarkan aspek penilaian pada Learning object Review Instrument (LORI) oleh John Nesbit. Nilai rata-rata yang diperoleh dari ahli materi sebesar 3,65 (sangat baik), ahli media 3,50 (sangat baik) dan ahli desain pembelajaran 3,70 (sangat baik). Hasil evaluasi pengguna dengan skala Guttman, memperoleh respon setuju dari 10 indikator. Berdasarkan hasil evaluasi tersebut dinyatakan Learning object sudah layak untuk digunakan sesuai dengan kebutuhan, serta tujuan pembelajaran. Hasil evaluasi oleh siswa sebagai pengguna, menyatakan bahwa Learning object memiliki tampilan yang menarik, inovatif, kreatif dan dapat digunakan oleh siswa.

This development research aims to produce a Learning object for Economics Subject, with the topic of Market Balance and Structure for class X students of SMA Labschool Jakarta. The development procedure used is the Rapid Prototyping Model by Tripp & Bichelmeyer. Learning object evaluation was carried out through expert review and one-to-one evaluation involving 2 material experts, 1 learning design expert, 2 media experts, and 2 users, which were measured based on the assessment aspects of the Learning Object Review Instrument (LORI) by John Nesbit. The average value obtained from the material expert is 3.65, the media expert is 3.50 and the learning design expert is 3.70. The results of the user evaluation with the Guttman scale, obtained an agree response from 10 indicators. Based on the results of the evaluation, it was stated that the Learning object was feasible to be used according to the needs and learning objectives. The results of the evaluation by students as users, stated that the Learning object has an attractive, innovative, creative appearance and can be used by students.
Multiple parallel origins of parasitic Marine Alveolates
Authors: Holt Corey C. , Hehenberger Elisabeth , Tikhonenkov Denis V. , Jacko-Reynolds Victoria K. L. , Okamoto Noriko , Cooney Elizabeth C. , Irwin Nicholas A. T. , Keeling Patrick J. 
Published: May 2023

Abstract
Microbial eukaryotes are important components of marine ecosystems, and the Marine Alveolates (MALVs) are consistently one of the most abundant and diverse groups of eukaryotes in global environmental sequencing surveys. Relatives of the dinoflagellates, MALVs are thought to be parasites of animals and other protists but the absence of data beyond ribosomal RNA gene sequences from all but two species means much of their biology and evolution remain unknown. Here we show that MALVs evolved independently from two distinct, free-living ancestors and that parasitism evolved twice, in parallel, prior to the divergence of the core dinoflagellates. Phylogenomics shows one subgroup (MALV II and IV, or Syndiniales) to be related to a novel lineage of free-living, eukaryovorous predators, the eleftherids, while the other (MALV I, now the Ichthyodiniales) is related to Oxyrrhis marina. Reconstructing the evolution of photosynthesis, plastids, and parasitism in early-diverging dinoflagellates show a number of parallels with the evolution of their sister group, the parasitic apicomplexans. In both groups, similar forms of parasitism evolved multiple times, photosynthesis was lost many times, and the plastid organelle was lost infrequently, leaving no trace in the genome that they ever existed.
Association analysis of nursing humanistic care demands and psychological distress in cancer surgery patients: A cross-sectional study
Authors: Ma Fengyan , Zhu Yajing , Liu Yan , Liu Lu 
Published: May 2023

Abstract
Objective To explore the associations between psychological distress and nursing humanistic care demands
Methods
A total of 432 cancer patients were recruited and surveyed using the General Questionnaire, the Distress Management Screening Measure, and Nursing Humanistic Care Demands Questionnaire. Pearson correlation analysis was applied in SPSS.24 to test the relationship between psychological distress and nursing humanistic care demands.
Results
The average psychological distress score of cancer patients was (3.95±2.71), of which 212 cases of significant psychological distress (DT≥4) were detected, with a detection rate of 49.1%. The main problems in the problem list that caused psychological distress to the patients were worrying in 226 cases (52.3%), financial problems in 176 cases (40.7%), and surroundings in 176 cases (40.7%). The average score of nursing humanistic demands was （147.02±19.88）, There was a positive correlation between the level of patient psychological distress and nursing humanistic care demands (r=0.418, P<0.001). The multiple stratified regression analysis results showed that the nursing humanistic care demands were included in the model of factors influencing psychological distress (F= 82.749, P＜0.001). It could independently explain 27.5% of the variance in psychological distress.
Conclusion
Cancer patients have a high detection rate of psychological distress and a high level of nursing humanistic care demands. Nursing staff should pay attention to the psychological state of patients and alleviate their psychological distress by carrying out measures of personalized humanistic care.
Insulin signaling is critical for sinoatrial node maintenance and function
Authors: Kim Jaetaek , Ock Sangmi , Lee Wang Soo , Choi Seung Hee , Kang Hyun , Kim Sung Joon , Choi Seong Woo 
Published: May 2023

Abstract
Background
Insulin and insulin-like growth factor 1 (IGF-1) signaling regulate cellular growth and glucose metabolism in the myocardium. However, their physiological role in cardiac conduction cells has never been explored. Therefore, we sought to determine the spatiotemporal function of insulin/IGF-1 receptors in the sinoatrial node (SAN).
Methods
We generated cardiac conduction cell-specific inducible IGF-1 receptor (IGF-1R) knockout (KO) (CSIGF1RKO), insulin receptor (IR) KO (CSIRKO), and IR/IGF-1R double KO (CSDIRKO) mice and evaluated their phenotypes.
Results
Telemetry measured electrocardiography found regular sinus rhythm in CSIGF1RKO mice, indicating that IGF-1R is dispensable for normal pacemaking. In contrast, CSIRKO and CSDIRKO mice exhibited profound sinus bradycardia. CSDIRKO mice showed a typical sinus node dysfunction characterized by junctional rhythm and sinus pauses on electrocardiography. Interestingly, the lack of an insulin receptor in the SAN cells of CSIRKO and CSDIRKO mice caused sinus nodal fibrosis. Mechanistically, hyperpolarization-activated cyclic nucleotide-gated channel 4 (HCN4) protein expression significantly decreased in the CSIRKO and CSDIRKO mice relative to the controls. A patch-clamp study of the SAN cells of CSIRKO mice marked a significant decrease in the funny current, which is responsible for spontaneous diastolic depolarization in the SAN. This result suggested that insulin receptor loss reduces the heart rate via downregulation of the HCN4 channel. Additionally, HCN1 expression was decreased in CSDIRKO mice explaining sinus node dysfunction.
Conclusion
Our results reveal a previously unrecognized insulin/IGF-1 signaling role in the sinus node structural maintenance and pacemaker function.
Assessment of war impact on concentrations of pollutants and heavy metals and their seasonal variations in water and sediments of the Tigris River in Mosul / Iraq
Authors: Altahaan Zena Fakhri , Dobslaw Daniel 
Published: May 2023

Abstract
War-related contamination of water and sediment of the Tigris River within the urban area of Mosul leads to seasonally independent exceedances of the WHO limit values for Cd, Pb, Cr, and Ni up to a factor of 100 in water and sediments. Furthermore, exceedances consistently occur for conductivity, PO43-, and SO42-, as well as sporadically for salinity and COD in water samples, and consistently for salinity in sediment samples, highlighting the direct impact of war (amunition, ignition of sulfur fields) as well as indirect effects (destroyed wastewater infrastructure). Conflict-related emissions from the former conflict zone (S5-S7) are highlighted by the sudden increases in load from S4 to S5, although partially masked by discharge of highly polluted water from the Khosr River (between S3 and S4). Due to sorption to sediments and presumed wind-borne discharge of highly polluted particles into the Tigris River, sediments at S10 on the southern edge of Mosul showed the highest pollutant loads. Significant statistical differences were observed by T-test analyses for E.C., TDS, salinity, COD, PO43-, NO3-, SO42-, Cd, Pb, Zn, Cr, and Ni for water samples as well as salinity, Cd, Pb, Zn, and Cr for the sediment samples for seasonal comparison. Since the percentage difference of water samples at S4-S7 is smaller than upstream and downstream, contaminant input is not limited to rainwater, but also via year-round infiltration of highly polluted wastewater from the surrounding valleys or suburban areas as well as presumably polluted groundwater or windblown particulate input.
Knowledge, attitude and practices of healthcare-seeking behaviour in leptospirosis among farmers in a Medical Officer of Health area in Sri Lanka – a cross sectional study in lower-middle income country
Authors: Dhanasinghe Chiranthi , Gamage Deepa 
Published: April 2023

Abstract
Background Leptospirosis is with a relatively high disease burden with significant mortality mainly affecting working age population in Sri Lanka. In its secondary prevention, early health-care seeking is given priority. The aim of the study was to describe the knowledge, attitude and practices of healthcare-seeking behaviour in leptospirosis among farmers in Pelmadulla Medical Officer of Health (MOH) area.Methods A community-based cross-sectional study was conducted among paddy farmers in the Pelmadulla MOH area. The cluster-sampling method was used taking a farming community as a cluster unit. Pre-tested interviewer-administered questionnaire was utilized by trained interviewers. Scoring systems for knowledge, attitude and practices were developed using expert inputs. Descriptive statistics were used.Results The response rate was 97% with 426 farmers being recruited. The majority of farmers were between 40 to 59 years. Male to female ratio was 10 to 1. The mean (SD) knowledge, attitudes and practice scores on health care seeking were; 7.17(1.59), 5.14(2.96) and 7.78 (2.7) respectively. The majority, 66% (n = 281) of the study sample had the good knowledge of healthcare-seeking behaviour in leptospirosis, out of all the participants, 13.6% (n = 58) had zero total attitude score, with 50% categorized as poor, while 50% (n = 213) of the study sample had a good attitude. Only, 25.1% (n = 107) of the study sample had a good practice score.Conclusion About half of the study population had good knowledge and attitudes but evident poor practice of healthcare-seeking behaviour in the study sample. The identified deficiencies need to be addressed through targeted programs.
Spectral coherence of soil thermal conditions and a stochastic inverse solution for thermal conductivity in the shallow vadose zone of Quaternary gravel formation
Authors: Shih David Ching-Fang 
Published: May 2023

Abstract
Due to the heterogeneity in the unsaturated or vadose zone, it is challenging to represent the analytical mechanism and actual in-situ water content in the soil layer. However, in the shallow layers, thermal conditions quickly change with surface temperature evolution. It expects that the water content can, more or less, be affected by the in situ heat mechanism. This research, therefore, suggests a novel design to theoretically discover the thermal conditions, such as soil temperature, soil temperature gradient, and heat flux in the shallow Quaternary gravel layer at various depths using spectral analysis of temporal observations. In addition, this research proposes a stochastic inverse solution of thermal conductivity using spectral estimation of soil heat flux and temperature gradient. It suggests that the most apparent periodic fluctuations of the thermal condition are in the diurnal process for 24 hours. The soil temperature gradient and heat flux at 10, 30, 60, and 120 cm depths can catch soil temperature and air temperature changes to some degree in the frequency domain. The thermal conductivity ranges from about 0.41 to 5.44 W/(m°C) for the soil depths from 10 to 120 cm using the inverse spectral solution. Thus, using spectral analysis, assessing the soil layer's thermal conductivity and other thermal conditions becomes feasible and achievable.
A comparison of surgical procedure cognitive skills acquisition between the traditional apprenticeship and a digital approach
Authors: Motsumi Mpapho Joseph , Brand Martin , Lubbe irene , Mokgatlhe Lucky 
Published: May 2023

Abstract
Background: The apprenticeship model of surgical training is the gold standard worldwide. However, increasing evidence shows that its traditional method of teaching surgical procedures covers cognitive skills inadequately. Therefore, the traditional teaching method for surgical procedures may be liable for producing surgeons who are not fully proficient in cognitive decision-making. This study designed a digital teaching method for surgical procedure cognitive skills and compared it to the traditional teaching method.
Methods: This was a quantitative experimental study conducted in two phases. Participants were novice medical officers and general surgery residents at the Universities of Botswana and Pretoria. Ethical approval was obtained. The digital teaching method was designed using the ADDIE model and compared to the traditional teaching method. ADDIE is an iterative instructional design model composed of five stages: Analysis, Design, Development, Implementation and Evaluation. A crossover-repeated-measures study design was used to determine the difference in knowledge gain and retention between the two teaching methods. A satisfaction level survey was also conducted.
Results: The digital teaching method for surgical procedure cognitive skills was designed and hosted on Moodle. Twenty-nine participants completed the study. The paired sample t-test showed that the mean differenced score for the digital teaching method (M = 3.59, SD = 1.48) was significantly greater than that of the traditional teaching method (M = 1.93, SD = 1.28), t (28) = -10.950, p < 0.001. Likewise, the mean differenced retention score for the digital teaching method (M = 2.96, SD = 1.480) was significantly higher than that of the traditional teaching method (M = 1.48, SD = 1.087). Seventy-two percent preferred the digital teaching method over the traditional one.
Conclusion: Students taught surgical procedure cognitive skills using the digital teaching method had better knowledge gain and retention than those taught using the traditional teaching method. Participants rated the digital teaching method highly compared to the traditional method. We recommend the adoption of the digital teaching method for teaching surgical procedure cognitive skills to produce surgeons competent in decision-making. The assumption is that this would lead to improved surgical outcomes.
The role of Interleukin-18 and interleukin-18 binding protein in K/BxN serum transfer- induced arthritis
Authors: Fauteux-Daniel Sebastien , Pich Laura M. Merlo , Girard-Guyonvarc’h Charlotte , Caruso Assunta , Rodriguez Emiliana , Gabay Cem 
Published: May 2023

Abstract
Background: Interleukin-18 is a proinflammatory cytokine, the activity of which is regulated by its natural inhibitor IL-18 binding protein (IL-18BP). Elevated circulating levels of IL-18 have been observed in patients with systemic juvenile idiopathic arthritis (sJIA) and adult-onset Still’s disease (AOSD), two conditions associated with dysregulated innate immune responses. This study examines the expression and function of IL-18 and IL-18BP in K/BxN serum transfer arthritis (STA), a model that is uniquely dependent on innate immune responses.
Methods: Naïve and STA wild-type (WT) mice were used to examine the articular levels of IL-18 and IL-18BP mRNA by RT-qPCR. The cellular sources of IL-18BP in the joints were determined by using Il18bp-tdTomato reporter knock-in mice. The incidence and severity of arthritis, including mRNA levels of different cytokines, were compared in IL-18BP or IL-18 knock-out (KO) mice and their WT littermates.
Results: IL-18 and IL-18BP mRNA levels were significantly increased in arthritic as compared to normal joints. Synovial neutrophils, macrophages and endothelial cells represented the cellular sources of IL-18BP in arthritic joints, whereas IL-18BP production was limited to endothelial cells in non-inflamed joints. The incidence and severity of arthritis was similar in IL-18BP KO and IL-18 KO compared to their WT littermates. Transcript levels of different inflammatory cytokines were not different in the two KO mouse lines compared to WT mice.
Conclusion: Although IL-18 and IL-18BP levels were increased in arthritic joints, our results show that the IL-18/IL-18BP balance is not involved in the regulation of STA.