bluuebunny/crossref_metadata_2025_split huggingface dataset:
Co-occurring ripple oscillations facilitate neuronal interactions between cortical locations in humans
Authors: Verzhbinsky Ilya A. , Rubin Daniel B. , Kajfez Sophie , Bu Yiting , Kelemen Jessica N. , Kapitonava Anastasia , Williams Ziv M. , Hochberg Leigh R. , Cash Sydney S. , Halgren Eric 
Published: May 2023

SUMMARYSynchronous bursts of high frequency oscillations (‘ripples’) are hypothesized to contribute to binding by facilitating integration of neuronal firing across cortical locations. We tested this hypothesis using local field-potentials and single-unit firing from four 96-channel microelectrode arrays in supragranular cortex of 3 patients. Neurons in co-rippling locations showed increased short-latency co-firing, prediction of each-other’s firing, and co-participation in neural assemblies. Effects were similar for putative pyramidal and interneurons, during NREM sleep and waking, in temporal and Rolandic cortices, and at distances up to 16mm. Increased co-prediction during co-ripples was maintained when firing-rate changes were equated, and were strongly modulated by ripple phase. Co-ripple enhanced prediction is reciprocal, synergistic with local upstates, and further enhanced when multiple sites co-ripple. Together, these results support the hypothesis that trans-cortical co-ripples increase the integration of neuronal firing of neurons in different cortical locations, and do so in part through phase-modulation rather than unstructured activation.
Spider: a flexible and unified framework for simulating spatial transcriptomics data
Authors: Yang Jiyuan , Qu Yang , Wei Nana , Hu Congcong , Wu Hua-Jun , Zheng Xiaoqi 
Published: May 2023

AbstractSpatial transcriptomics technology provides a valuable view for studying cellular heterogeneity due to its ability to simultaneously acquire gene expression profile and cell location information. However, benchmarking these rapidly accumulating spatial transcriptomics analysis tools is challenging owing to the limited diversity and accuracy of “gold standard” data sets annotated by pathologists. To address this issue, we proposed Spider, a flexible and unified simulator for spatial transcriptomics data guided by cell type proportion and transition matrix of adjacent cell types. Taking advantage of a heuristic batched simulated annealing algorithm (BSA) in assigning simulated cell type labels, Spider can generate spatial transcriptomics data for one million cells in just five minutes. Furthermore, Spider can generate various types of spatial transcriptomics data, including immune hot/cold tumor samples by specifying different immune cell proportions and transition matrices and layered tissue samples via an interactive interface. In addition, Spider is also a unified framework for ST data simulation in which we have implemented diverse simulators proposed by other researchers as special cases. We have systematically evaluated the performance of Spider and competing tools, and demonstrated Spider’s remarkable power to capture the spatial pattern of the reference dataset. Spider is available athttps://github.com/YANG-ERA/Artist.
IL-1β promotes MPN disease initiation by favoring early clonal expansion ofJAK2-mutant hematopoietic stem cells
Authors: Rai Shivam , Zhang Yang , Grockowiak Elodie , Kimmerlin Quentin , Hansen Nils , Stoll Cedric B. , Usart Marc , Hao-Shen Hui , Bader Michael S. , Passweg Jakob R. , Dirnhofer Stefan , Farady Christopher J. , Schroeder Timm , Méndez-Ferrer Simón , Skoda Radek C. 
Published: May 2023

AbstractJAK2-V617F is the most frequent somatic mutation causing myeloproliferative neoplasm (MPN). However,JAK2-V617F can also be found in healthy individuals with clonal hematopoiesis of indeterminate potential (CHIP) with a frequency much higher than the prevalence of MPN. The factors controlling the conversion ofJAK2-V617F CHIP to MPN are largely unknown. We hypothesized that IL-1β mediated inflammation is one of the factors that favors this progression. We examined mono- or oligoclonal evolution of MPN by performing bone marrow transplantations at limiting dilutions with only 1-3JAK2-mutant HSCs per recipient. Genetic loss ofIL-1βinJAK2-mutant hematopoietic cells or inhibition by a neutralizing anti-IL-1β antibody restricted the early clonal expansion of theseJAK2-mutant HSCs resulting in a reduced frequency of a CHIP-like state and a lower rate of conversion to MPN. The MPN disease-promoting effects of IL-1β were associated with damage to sympathetic innervation leading to loss of nestin-positive mesenchymal stromal cells and required the presence ofIL-1R1on bone marrow stromal cells. The anti-IL-1β antibody protected these mesenchymal stromal cells from IL-1β mediated damage and limited the expansion of theJAK2-mutant clone. Our results identify IL-1β as a potential therapeutic target for preventing the transition fromJAK2-V617F CHIP to MPN.Brief summaryIn a mouse model of oligo-clonal myeloproliferative neoplasm (MPN), IL-1β produced byJAK2-mutant cells favored expansion of sub-clinicalJAK2-V617F clones and initiation of MPN disease.
The effect of rising food prices on nutrient intake among rural–urban migrants in China
Authors: Li Lei , Bai Junfei , Zhu Qiubo 
Published: May 2023

PurposeThe purpose of this study is to assess the impact of rising food prices on food demand and nutrient intake among rural–urban migrants and whether such impact varies across income classes.Design/methodology/approachUsing data from the China Health and Nutrition Survey (CHNS), this study adopts a quadratic almost ideal demand system (QUAIDS) for food demand elasticity and an indirect estimation method for nutrient elasticity to investigate the effects of rising food prices on food demand and nutrient intake among rural–urban migrants.FindingsThe estimated results indicate that an increase in the price of pork alone would lead to a larger reduction in most nutrients among rural–urban migrants than other single targeted food group, and a simultaneous rise in the price of all food groups would have a remarkably adverse effect on the nutritional status of rural–urban migrants in comparison to the nutritional effects of a rise in one targeted food group. In addition, the nutritional effects of food prices across income classes show that the nutritional status is particularly vulnerable to rising food prices among low-income rural–urban migrants.Originality/valueThis paper focuses on analyzing the impact of rising food prices on the nutritional status of rural–urban migrants, a topic that is very limited in the literature. This study provides a fresh look at the effect of volatile food prices on food demand and nutrient intake among rural–urban migrants. The results indicate that income growth would have a remarkable positive effect on nutrient intake for rural–urban migrants, especially for low-income rural–urban migrants. However, an increment in nutrients due to a growth in income would not be far from enough to cover the reduction in nutrients as a result of a simultaneous rise in price of all the studied food categories at the same rate.
Stakeholder theory, risk-taking and firm performance
Authors: Dao Thi Thanh Binh , Phan Minh Chau 
Published: May 2023

Purpose
This study, using stakeholder approach, aims to examine the impact of corporate governance and risk-taking on the performance of the top 100 nonfinancial listed firms in Vietnam from 2015 to 2019.

Design/methodology/approach
The theoretical and empirical studies are reviewed for rational hypotheses development. Firm performance is represented by return on assets, return on equity and Tobin’s Q.

Findings
Specifically, concentrated ownership structure, large workforce, being a great workplace, quick sales growth, high receivables turnover, being funded by both the state and foreigners and high-risk exposure positively affect firm performance. However, a high level of state ownership or foreign ownership, more independent members on board, large board size and chief executive officer (CEO) duality show an inverse effect. Besides, an inverted U-shaped relationship with firm performance is recognized for liquidity ratios.

Originality/value
This study uses three triangles, including governance, risk, and performance. The paper offers some evidence-based recommendations to improve firm performance in Vietnamese businesses.
Design advantages and analysis of a novel five-phase doubly-fed induction generator
Authors: Ryndzionek Roland , Michna Michal , Kutt Filip , Kostro Grzegorz , Blecharz Krzysztof 
Published: May 2023

Purpose
The purpose of this paper is to provide an analysis of the performance of a new five-phase doubly fed induction generator (DFIG).

Design/methodology/approach
This paper presents the results of a research work related to five-phase DFIG framing, including the development of an analytical model, FEM analysis as well as the results of laboratory tests of the prototype. The proposed behavioral level analytical model is based on the winding function approach. The developed DFIG model was used at the design stage to simulate the generator’s no-load and load state. Then, the results of the FEM analysis were shown and compared with the results of laboratory tests of selected DFIG operating states.

Findings
The paper provides the results of analytical and FEM simulation and measurement tests of the new five-phase dual-feed induction generator. The use of the MATLAB Simscape modeling language allows for easy and quick implementation of the model. Design assumptions and analytical model-based analysis have been verified using FEM analysis and measurements performed on the prototype. The results of the presented research validate the design process as well as show the five-phase winding design advantage over the three-phase solution regarding the control winding power quality.

Research limitations/implications
The main disadvantage of the winding function approach-based model development is the simplification regarding omitting the tangential airgap flux density component. However, this fault only applies to large airgap machines and is insignificant in induction machines. The results of the DFIG analyses were limited to the basic operating states of the generator, i.e. the no-load state, the inductive and resistive load.

Practical implications
The novel DFIG with five phase rotor control winding can operate as a regular three-phase machine in an electric power generation system and allows for improved control winding power quality of the proposed electrical energy generation system. This increase in power quality is due to the rotor control windings inverter-based PWM supply voltage, which operates with a wider per-phase supply voltage range than a three-phase system. This phenomenon was quantified using control winding current harmonic analysis.

Originality/value
The paper provides the results of analytical and FEM simulation and measurement tests of the new five-phase dual-feed induction generator.
The supportability evaluation of cross-regional major infrastructure projects based on the combination weighting of the game theory–cloud model
Authors: Zhang Minggong , Xue Xiaolong , Luo Ting , Li Mengmeng , Tang Xiaoling 
Published: May 2023

PurposeThis study aims to establish an evaluation method for cross-regional major infrastructure project (CRMIP) supportability. The focus is to identify evaluation indicators from a complexity perspective and develop an evaluation model using qualitative and quantitative methods. Case studies are carried out to verify the reliability of the evaluation model, thereby providing theoretical and practical guidance for CRMIP operations and maintenance (O&M).Design/methodology/approachGuided by the idea of complexity management, the evaluation indicators of CRMIP supportability are determined through literature analysis, actual O&M experience and expert interviews. A combination of qualitative and quantitative methods, consisting of sequential relationship analysis, entropy weighting, game theory and cloud model, is developed to determine the indicator weights. Finally, the evaluation model is used to evaluate the supportability of the Hong Kong–Zhuhai–Macao Bridge (HZMB), which tests the rationality of the model and reveals its supportability level.FindingsThe results demonstrate that CRMIPs' supportability is influenced by 6 guideline-level and 18 indicator-level indicators, and the priority of the influencing factors includes “organization,” “technology,” “system,” “human resources,” “material system,” and “funding.” As for specific indicators, “organizational objectives,” “organizational structure and synergy mechanism,” and “technical systems and procedures” are critical to CRMIPs' O&M supportability. The results also indicate that the supportability level of the HZMB falls between good and excellent.Originality/valueUnder the guidance of complexity management thinking, this study proposes a supportability evaluation framework based on the combined weights of game theory and the cloud model. This study provides a valuable reference and scientific judgment for the health and safety of CRMIPs' O&M.
The self-perceived age of GenX women: prioritising female subjective age identity in marketing
Authors: Gillooley Sharon-Marie , Resnick Sheilagh Mary , Woodall Tony , Allison Seamus 
Published: May 2023

Purpose
This study aims to examine the phenomenon of self-perceived age (SPA) identity for Generation X (GenX) women in the UK. Squeezed between the more ubiquitous “boomer” and “millennial” cohorts, and now with both gender and age stigma-related challenges, this study looks to provide insights for understanding this group for marketing.

Design/methodology/approach
This study adopts an existential phenomenological approach using a hybrid structured/hermeneutic research design. Data is collected using solicited diary research (SDR) that elicits autoethnographic insights into the lived experiences of GenX women, these in the context of SPA.

Findings
For this group, the authors find age a gendered phenomenon represented via seven “age frames”, collectively an “organisation of experience”. Age identity appears not to have unified meaning but is contingent upon individuals and their experiences. These frames then provide further insights into how diarists react to the stigma of gendered ageism.

Research limitations/implications
SDR appeals to participants who like completing diaries and are motivated by the research topic. This limits both diversity of response and sample size, but coincidentally enhances elicitation potential – outweighing, the authors believe, these constraints. The sample comprises UK women only.

Practical implications
This study acknowledges GenX women as socially real, but from an SPA perspective they are heterogeneous, and consequently distributed across many segments. Here, age is a psychographic, not demographic, variable – a subjective rather than chronological condition requiring a nuanced response from marketers.

Originality/value
To the best of the authors’ knowledge, this is the first formal study into how SPA identity is manifested for GenX women. Methodologically, this study uses e-journals/diaries, an approach not yet fully exploited in marketing research.
Anti-corruption disclosure quality and earnings management in the United Kingdom: the role of audit quality
Authors: Salem Rami Ibrahim A. , Ghazwani Musa , Gerged Ali Meftah , Whittington Mark 
Published: May 2023

Purpose
Building upon institutional pressures on firms to deal with corruption, this study aims to investigate the association between a firm's engagement with anti-corruption disclosure quality (ACD_Q) and earnings management (EM). Also, this study examines the moderating role of audit quality in the association between ACD_Q and EM.

Design/methodology/approach
The authors constructed an ACD_Q index based on the 2010 UK Bribery Act and taking into account a wide range of rules on corruption and bribery, including those of the OECD, World Bank, UNCTAD, UNGC, UNCAC and GRI. Generalized method of moments and panel regression were used to examine the association between ACD_Q and EM.

Findings
Using a sample of 2,695 firm‐year observations of the UK’s FTSE-350 from 2008 to 2018, this study finds ACD_Q is negatively associated with EM. In addition, this negative relationship is contingent on audit committee independence and audit committee expertise. This finding is supported by additional robustness and sensitivity analysis.

Practical implications
The empirical evidence reiterates the crucial need for more concerted efforts to ensure corporate engagement in anti-corruption practices with a view to reducing earnings manipulations.

Originality/value
This study contributes to the limited evidence that investigates how ACD Q influences EM in the UK after the introduction of the UK Bribery Act in 2010. Furthermore, by considering the period from 2008 to 2019, this study investigates the potential moderating role of UK corporate governance reforms in EM reduction. In particular, to the best of the authors’ knowledge, this study assesses for the first time the moderating effect of audit committee mechanisms on the ACD Q and EM nexus.
The impact of maritime service quality on employee satisfaction by seafarers rank: evidence from a global survey grounded on ERG theory
Authors: Pantouvakis Angelos , Vlachos Ilias , Polemis Dionysios 
Published: May 2023

PurposeThis study aims to reveal the constituents of seafaring service quality (physical and social environment) and their effects on seafarer employee satisfaction (job satisfaction and turnover intention) and analyse any differences among seafarer ranks. Literature on service quality has overlooked the transportation sector and seafaring in particular.Design/methodology/approachSeafaring service quality is measured by the workplace environment constituted of physical and social environments. Two types of employee (job) satisfaction were explored: overall job satisfaction and turnover intention. This study is based on a unique, large survey based on the Existence-Relatedness-Growth (ERG) needs theory. An exploratory factor analysis revealed four physical environment factors (Ship conditions, Communication facilities, Nautical health and Living conditions) and four social environment factors (Social fit, Team cohesion, Ship company support and Intercultural environment). Multi-group regression analysis assessed the effects of seafaring service quality on employee satisfaction.FindingsThe social environment has stronger effects than the physical environment on job satisfaction but not on employee retention. Team cohesion has strong effects on employee retention, while social fit has stronger effects on overall job performance. Seafarer ranks showed significant variations. The physical environment matters for 2nd engineers' and cadets’ job satisfaction but not for ratings, masters and chief officers. Team cohesion is significant to master, chief officer, engineer and cadet ranks but not for junior officers and ratings. Social fit has stronger effects on overall job performance than employee retention, particularly for ratings, cadets, master, chief officer and chief engineer ranks. Ship company support has the stronger effect on overall job satisfaction among all workplace factors; this is also observed across all ranks.Research limitations/implicationsMotivation theories like the ERG theory can help understand service quality and employee satisfaction in the maritime sector; future studies should examine more behaviour variables/constructs from these theories.Practical implicationsMaritime companies can offer better services to seafarers, who are considered as key workers, by customising their interventions to specific seafarer ranks and developing a supportive culture that improves seafarer well-being.Originality/valueThis study examined the overlooked topic of maritime service quality based on a large-scale survey grounded on ERG theory and reveals how the physical and social environment has different effects on seafarer job satisfaction and retention.
Value-added service investment and pricing decisions in two-sided platform: the role of user expectations
Authors: Gui Yunmiao , Zhai Huihui , Dong Feng , Liu Zhi 
Published: May 2023

PurposeThis paper aims to investigate how user expectations affect value-added service (VAS) investment and pricing decisions of two-sided platforms. It draws on the information asymmetry theory and offers suggestions on how platform operators can manage user expectations.Design/methodology/approachAccording to the game theory, this study considers three user expectations (responsive, passive and wary). By framing the Hotelling duopoly model and comparing the VAS investment, price and platform profits, the optimal platform decision is analyzed and discussed.FindingsThe conclusions demonstrate that the monopolistic two-sided platform obtains more profits from the informed users with responsive expectations than uninformed users with passive or wary expectations. The marginal investment cost and cross-network externalities are two key factors that determine the platform's VAS investment and pricing strategies of passive or wary users. Furthermore, considering the expectation preferences, i.e. the uniformed users hold wary expectations with more information and hold passive expectations with less or no information, the results suggest that the proportion of wary users to all uninformed users increases the platform's VAS investment, profits and the price of informed users, and increase (decrease) the price of uninformed users when the cross-network externalities of informed users are relatively small (larger).Practical implicationsThese results can provide insightful enlightenment into how platform operators utilize bilateral users' expectations and information level to guide their VAS investment and pricing decisions.Originality/valueThis paper is one of the first to explore the impact of three user expectations and the heterogeneity of preferences in informing users' passive or wary expectations, based on different levels of information on the decision-making of two-sided platforms regarding VAS.