bluuebunny/crossref_metadata_2025_split huggingface dataset:
Europe against Revolution
Authors: Lok Matthijs 
Published: March 2023

Abstract
The revolutionary thesis of this book is that the European past and the idea of Europe as an essentially ‘historical continent’ was (re)invented by the critics of the French Revolution as part of their ideological struggle against the Revolution. The counter-revolutionary authors and statesmen were both conservative and cosmopolitan at the same time. In their writings they drew on the works of the eighteenth-century Enlightenment as well as criticized its alleged revolutionary legacy. This study seeks to uncover the roots of historically informed ideas of Europe and of European history, while at the same time underlining the fundamental differences between the writings of the older counter-revolutionary Europeanists and their self-appointed successors in the twenty-first century.
Vienna as a Missed Opportunity
Authors: Lok Matthijs 
Published: March 2023

Abstract
The eighth chapter (‘Vienna as a Missed Opportunity’) treats the collapse of the Napoleonic Order in 1814–15 as a moment for European renewal and regeneration. The Vienna Congress is situated in the context of the ‘European moment’ of 1814–15, when writers from all geographical backgrounds and political convictions believed that a new European political and religious order was imminent. It will be argued that the Vienna order was inspired by enlightened cosmopolitan ideals of peace, as well as by pluralist historical narratives of Europe. Rather than a moment of spiritual and religious regeneration, Vienna turned out, in the eyes of counter-revolutionary Europeanists such as Joseph de Maistre, to be a disappointing pragmatic compromise with revolutionary ideals.
Bits, Bytes, Searches, and Hits: Logging-in Accountability for EU Data-led Security
Authors: Curtin Deirdre , Goede Marieke de 
Published: March 2023

Abstract
EU data-led and interoperable security poses profound challenges to democratic control and to the normative principles of legal protection and accountability. This chapter analyses the ad hoc practices of accountability that are developing in relation to the actors and instruments in a number of EU security programmes and assesses their ‘loggedness’ in relation to data. The aim is twofold. First, the chapter offers a mapping exercise in relation to accountability practices in a selection of established and emerging database configurations in the EU security realm. The focus is on four security programmes that operate across national boundaries and across public and private spheres: EU-TFTP, TERREG, ETIAS, and ECRIS-TCN. Second, it assesses the extent to which the selected mechanisms are ‘logged-in’ to the work of data analysis that they are expected to give account of. In conclusion, the authors reflect on what a fuller, more meaningful ‘logged-in’ accountability in relation to data-led security could and should look like, both in terms of institutions and digital practices.
A New Latin Poem by Joseph Addison
Authors: Davis Paul 
Published: March 2023

Abstract
Known almost exclusively now as the author of The Spectator and Cato, Joseph Addison was also highly regarded throughout the eighteenth and nineteenth centuries as a Latin poet. This article presents a new addition to the canon of Addison’s Latin verse: a 57-line hexameter poem entitled Arcus Triumphalis which survives in a unique manuscript copy recently acquired by Addison’s alma mater Magdalen College, Oxford. The article begins by describing the manuscript (scans of the leaves containing Addison’s poem are included), detailing its likely genesis and confirming its attribution of the poem to Addison. Then it reconstructs the contexts of the poem, which describes a firework display put on in St James’s Square on the evening of 2 December 1697 to celebrate William III’s triumphal return to London after concluding the Peace of Ryswick. A third section provides a critical reading of the poem, concentrating on its surprising presentation of William III and its bold use of ekphrasis. The article concludes by assessing the place of Arcus Triumphalis in Addison’s career, in relation to the early development of his Whiggism and as a forerunner of several of his definitive concerns in The Spectator: privacy and the public sphere, urban spectacle, and the aesthetics of looking. An edited text of the poem and an English translation are provided in an appendix.
Anti-nutritional and gas chromatography-mass spectrometry (GC-MS) analysis of ethanol root extract and fractions of Sphenocentrum jollyanum
Authors: Ugwu Okechukwu Paul-Chima , Alum Esther Ugo , Okon Michael Ben , Aja Patrick M , Obeagu Emmanuel I , Onyeneke E C 
Published: March 2023

Abstract

Objectives
The anti-nutritional composition and gas chromatography-mass spectrometry (GC-MS) analysis of ethanol root extract and fractions of Sphenocentrum jollyanum (SJ) were carried out.

Methods
The anti-nutritional factors and GC-MS were analysed using standard methods.

Key findings
The anti-nutritional constituents of the samples were in the order of phenols &gt; terpenoids &gt; flavonoids &gt; tannins &gt; glycosides &gt; alkaloids &gt; hydrogen cyanide &gt; saponins &gt; steroids. The phytochemicals were significantly (P &lt; 0.05) higher in extract than fractions, the terpenoids value obtained as 1904.72 mg/100 g from ethanol extract is significantly higher (P &lt; 0.05) than the values of 935.80 mg/100 g and 968.92 mg/100 g gotten from it ethyl acetate and methanol fractions, respectively. There is no significant difference (P &gt; 0.05) for the ethyl acetate 0.74 mg/100 g and methanol 0.79 mg/100 g fractions of steroids. However, the methanol fraction of tannins, phenols, glycosides, saponins and hydrogen cyanide were significantly higher than its ethyl acetate fractions.

Conclusion
Chromatogram of GC-MS analysis of the samples of SJ showed 49, 43 and 24 peaks for crude ethanol extract, ethyl acetate and methanol fractions, respectively. GC-MS analysis of the crude ethanol root extract and fractions as shown in Tables 2–4 contain hexadecanoic acid, oleic acid and nonanoic acid methyl ester. The ethyl acetate and methanol fractions of SJ contain 16.9 and 10.1% of 1, 2-benzenedicarboxylic acid, bis (8-methylnonyl) ester, respectively.
Emergency management capacity assessment for urban rail transit—an example of Beijing Metro Line 13
Authors: Liu Jiao , Qi Yun , Wang Wei 
Published: March 2023

Abstract
In order to improve the emergency management capability of urban rail transit system and reduce accidents during metro operation, an emergency management capability evaluation method combining analytic hierarchy process (AHP) and technique for order preference by similarity to ideal solution (TOPSIS) is proposed. Based on the Prevention Preparation Response Recovery (PPRR) model, factors influencing the emergency management capability of the urban rail transit system are summarized from the perspective of ‘human, machine, environment and management’. Then, an emergency management capability evaluation index system containing of 20 secondary indicators is constructed in four stages: emergency prevention, emergency preparation, emergency response and emergency recovery. The weights of indicators are calculated using the AHP method, and the closeness of each indicator to the optimal solution is analysed with the TOPSIS method. Finally, take the Beijing Metro Line 13 as an example to investigate the level of emergency management capability of urban rail transit. The results show that the emergency management capability of Beijing's urban rail transit system is ‘well’, among which hazard prevention measures (0.31) and emergency response team (0.34) have a greater weight on the emergency management capability of rail transit. The model can more accurately assess the emergency management capability of urban rail transit and provide a basis for emergency management.
Discovery of novel CDK2 inhibitors using multistage virtual screening and in vitro melanoma cell lines
Authors: Yang Lihong , Wang Mukuo , Li Beibei , Xu Shangqin , Lin Jianping 
Published: March 2023

AbstractCyclin‐dependent kinases 2 (CDK2) is a serine/threonine‐protein kinase, which plays a key role in the regulation of cell cycle and is related to the occurrence and development of melanoma. In this study, we identified potent inhibitors for CDK2 by combining a multistage virtual screening strategy with bioassay validations. The biochemical activity of compounds was validated with ADP‐Glo™ Kinase assay in vitro, and the results indicated that the biochemical activity of compound 1 (C1) was better than other selected compounds. Cell viability assay showed that the minimum inhibition concentration of C1 for CDK2 was lower than 4 μM. Further functional test results showed that C1 exerted significant antiproliferative, pro‐apoptosis, and anti‐migration activity in melanoma cell lines (A375 cells, WM35 cells, and A875 cells). Our findings suggested that the C1, virtually screened from compound libraries, as the novel inhibitor of CDK2, may be further developed as an effective therapeutic agent in the treatment of melanoma lines.
Back Pain and Quality of Life 10 Years After Segmental Pedicle Screw Instrumentation for Adolescent Idiopathic Scoliosis
Authors: Ahonen Matti , Syvänen Johanna , Helenius Linda , Mattila Mikko , Perokorpi Tanja , Diarbakerli Elias , Gerdhem Paul , Helenius Ilkka 
Published: March 2023

Study Design.
Comparative cohort study.

Objective.
The aim of the present study was to evaluate pain and health-related quality of life (HRQoL) in surgically managed patients with a minimum follow-up of 10 years compared with patients with untreated adolescent idiopathic scoliosis (AIS) and a healthy control group.

Summary of Background Data.
Posterior spinal fusion with pedicle screws is the standard treatment for AIS, although it remains unclear whether this procedure results in improved long-term HRQoL compared with untreated patients with AIS.

Patients and Methods.
Sixty-four consecutive patients at a minimum follow-up of 10 years, who underwent posterior pedicle screw instrumentation for AIS were prospectively enrolled. Fifty-three (83%) of these patients completed Scoliosis Research Society (SRS) 24 questionnaires, clinical examination, and standing spinal radiographs. Pain and HRQoL were compared with age and sex-matched patients with untreated AIS and healthy individuals.

Results.
The mean major curve was 57° preoperatively and 15° at the 10-year follow-up. SRS-24 self-image domain score showed a significant improvement from preoperative to 2 years and remained significantly better at the 10-year follow-up (P < 0.001). Patients fused to L3 or below had lower pain, satisfaction, and total score than patients fused to L2 or above (P < 0.05), but self-image, function, and activity scores did not differ between groups at 10-year follow-up. Pain, self-image, general activity, and total SRS domains were significantly better at 10-year follow-up in the surgically treated patients as compared with untreated patients (all P < 0.05). Healthy controls had significantly higher total scores than those surgically treated at 10-year follow-ups (P < 0.001).

Conclusion.
Patients undergoing segmental pedicle screw instrumentation for AIS maintain high-level HRQoL during a 10-year follow-up. Their HRQoL was significantly better than in the untreated patients with AIS, except for the function domain. However, HRQoL remained at a lower level than in healthy controls.
Fluconazole-Resistant Candida albicans Vaginal Infections at a Referral Center and Treated With Boric Acid
Authors: File Brittany , Sobel Ryan , Becker Mariel , Nyirjesy Paul 
Published: March 2023

Objective
The authors investigate the incidence of clinical and mycological resistance of Candida albicans vulvovaginitis (VVC) at the Jefferson Vulvovaginal Health Center. They also review their experience with boric acid in the treatment of fluconazole-resistant VVC.

Methods
The authors conducted a retrospective chart review of all patients with C. albicans VVC diagnosed at the Jefferson Vulvovaginal Health Center between November 2019 and December 2021. Patients with clinically defined fluconazole resistance were identified. Information about demographics, in vitro susceptibility testing, and treatment outcomes with boric acid was obtained.

Results
Of 970 patients with vaginal C. albicans isolates, 71 (7.3%) with clinically defined fluconazole-resistant C. albicans infections were identified. Relevant demographics included 45.1% African American, 43.7% aged younger than 30 years, and 43.7% with body mass index less than 25. Of the 71 patients, 58 (81.7%) received vaginal boric acid treatment. The mycological and clinical cure rates were 85.7% and 73.7%, respectively. After successful boric acid treatment and negative yeast cultures, 14.3% of patients had a mycological recurrence within 3 months. Of 31 isolates with antifungal susceptibility testing, 83.9% (26/31) were found to have minimal inhibitory concentration results consistent with fluconazole resistance.

Conclusions
In a tertiary care vulvovaginal health center, fluconazole-resistant Candida albicans VVC is by no means uncommon and usually responds in the short term to treatment with boric acid. However, in the absence of maintenance boric acid, recurrence of culture-positive VVC is likely.
Fibrin Glue–Coated Collagen Complex Patch: A Novel Material for Surgical Repair of Spontaneous Temporal Bone Cerebrospinal Fluid Leak and Encephalocele
Authors: Symms John Thomas , Dabecco Rocco , Ballard Daniel , Yu Alexander , Chen Douglas , Hillman Todd 
Published: March 2023

Objective
To compare outcomes of surgical repair of temporal bone encephalocele and cerebrospinal fluid (CSF) leak using fibrin glue–coated collagen (FGCC) complex patch versus other materials for repair of dura.

Study Design
Retrospective chart review.

Setting
Tertiary care hospital.

Patients
Fifty-two adult patients undergoing transmastoid (TM), middle fossa (MF) or combined approach repair of spontaneous MF CSF leak between 2016 and 2020.

Interventions
Exposure of bony defect via TM approach, MF craniotomy, or combined TM/MF, and repair of the associated dura defect with FGCC complex patch, or other materials (acellular collagen matrix, bovine collagen, autologous fascia, fibrin tissue sealant).

Main Outcome Measures
Successful repair without recurrent CSF leak or encephalocele throughout follow-up. Cost of materials used in duraplasty.

Results
Sixty-four percent of patients were female. Mean (standard deviation) age at repair was 61.4 (12.1) years. Mean (standard deviation) body mass index was 35.0 (8.3) kg/m2. Forty-nine (94%) patients had successful repair without known recurrence of CSF leak or encephalocele over a median follow-up interval of 11.7 months. Average duraplasty material cost was significantly lower with FGCC in comparison with other nonautologous materials (FGCC+: $1259.94, FGCC−: $1652.58; p = 0.004). No significant differences in recurrence risk (FGCC+: 6.9%, FGCC−: 6.9%; p > 0.999) or operative time (FGCC+: 153.7 min, FGCC−: 155.4 min; p = 0.88) were detected based on material used for duraplasty.

Conclusions
All materials studied demonstrate effective and sustained means of repair for MF CSF leak and encephalocele, including in the presence of multiple defects. Use of FGCC for duraplasty produces noninferior surgical results to other nonautologous materials in repair of spontaneous CSF leaks of the temporal bone and may be more cost-effective.
Maternal voice reduces procedural pain in neonates: A meta-analysis of randomized controlled trials
Authors: Jin Lingwen , Zhang Jing , Yang Xin , Rong Hui 
Published: March 2023

Background:
Procedural pain management is a very important part in the clinical care of neonates. We aimed to conduct a meta-analysis to evaluate the effects of maternal voice on neonatal procedural pain, to provide insights to the clinical pain care of neonates.

Methods:
Two researchers independently searched PubMed, EMBASE, The Cochrane Library, CINAHL, Web of Science, China Biomedical Literature Database, China National Knowledge Infrastructure, Wanfang and Weipu Database for randomized controlled trials (RCTs) involving the effects of maternal voice on the procedural pain of neonates up to October 25, 2022. Two investigators screened the literature based on the inclusion and exclusion criteria and evaluated the methodological quality of the inclusion study. RevMan 5.3 software was used for the meta-analysis.

Results:
A total of 8 RCTs with a total of 584 neonates were included. Our meta-analysis indicated that maternal voice reduces the pain score (SMD = −0.60, 95% CI: −0.81 to −0.39) and heart rate (SMD = −0.81, 95% CI: −1.44 to −0.18) and increases the comfort level (SMD = −0.47, 95% CI: −0.83 to −0.11) and blood oxygen saturation (SMD = 0.70, 95% CI: 0.03–1.38) during procedure (all P < .05). Moreover, maternal voice reduces the pain score (SMD = −0.58, 95% CI: −0.88 to −0.28) and heart rate (SMD = −0.44, 95% CI: −0.75 to −0.12) and increases the blood oxygen saturation (SMD = 0.41, 95% CI: 0.00 to −0.82) after procedure (all P < .05). No publication biases were detected by the funnel plots and Egger tests (all P > .05).

Conclusion:
Maternal voice is beneficial to reduce procedural pain and improve the physiological indicators in neonates. It is still necessary to conduct high-quality, large sample studies in the future to further elucidate the effect of maternal voice on neonatal pain care.
The effect of a gait and balance training program on an unstable mudflats surface in older adults: A randomized controlled pilot study
Authors: Lee Junekyung , Chun Min Ho , Lee Jiyeon 
Published: March 2023

Background:
Balance training on an unstable support surface has been known to improve postural control. The aim of this study was to investigate the effect of a gait and balance training program on an unstable mudflats surface in older adults.

Methods:
A total of 28 older people were assigned to participate in a gait and balance training program on an unstable mudflats surface (experimental group) or on firm ground (control group). All participants received the training program for 55 minutes per session, 2 sessions per day for 5 days. The primary outcomes were the Berg Balance Scale (BBS) and single-leg stance (SLS) test. Secondary outcomes were Timed Up and Go (TUG), 10-meter walk test (10MWT), Modified Falls Efficacy Scale (MFES), Motricity Index (MI) of the lower extremities, and medical research council (MRC) scale of lower extremities.

Results:
SLS with eyes open and the MRC of the left and right ankles showed a large effect size whereas the MI of the left and right lower extremities and MRC of the left and right knees showed a medium effect size in the experimental group. Intergroup differences in changes from baseline to after the exercise program included a large effect size of the SLS with eye open and MI of the right lower extremity and a medium effect size of the MI of the left lower extremity and MRC of the right ankle and left hip.

Conclusions:
Muscle strength and balance of older people could be improved with gait and balance training on an unstable mudflat surface.
The MRI features of renal inflammatory pseudotumor: A case report and literature review
Authors: Han Yang , Yang Guoqiang , Du Jiangfeng , Tan Yan , Zhang Hui 
Published: March 2023

Rationale:
Inflammatory pseudotumor is rare observed in renal immunoglobulin G4-related disease.

Patient concerns:
A 65-year-old female presented with a mass in the right kidney which was found in physical examination.

Diagnoses:
Based on the imaging findings and clinical manifestations, we preliminarily judged that the mass of the right kidney was renal cell carcinoma.

Interventions:
The patient finally underwent total nephrectomy.

Outcomes:
The final result of microscopic pathological examination is renal inflammatory pseudotumor.

Lessons:
There are some characteristics on magnetic resonance imaging of renal inflammatory pseudotumor, which can improve diagnosis rate by combining with medical history and clinical manifestations.
Efficacy and safety of early chest tube removal after selective pulmonary resection with high-output drainage: A systematic review and meta-analysis
Authors: Zhu Junwei , Xia Xueyang , Li Rongyao , Song Weikang , Zhang Zhiqiang , Lu Huawei , Li Zhiwei , Guo Qingwei 
Published: March 2023

Background:
There is controversy over the drainage threshold for removal of chest tubes in the absence of significant air leakage after selective pulmonary resection.

Methods:
A comprehensive search of online databases (PubMed, Web of Science, Embase, Cochrane Library, Scopus, Ovid, Elsevier, Ebsco, and Wiley) and clinical trial registries (WHO-ICTRP and ClinicalTrials.gov) was performed to investigate the efficacy and safety of early chest tube removal with high-output drainage. Primary outcome (postoperative hospital day) and secondary outcomes (30-day complications, rate of thoracentesis, and chest tube placement) were extracted and synthesized. Subgroup analysis, meta-regression, and sensitivity analysis were used to explore the potential heterogeneity. Study quality was assessed with the Newcastle-Ottawa Scale, and evidence was graded using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) assessment by the online GRADEpro Guideline Development Tool.

Results:
Six cohort studies with a total of 1262 patients were included in the final analysis. The postoperative hospital stay in the high-output group was significantly shorter than in the conventional treatment group (weighted mean difference: −1.34 [−2.34 to −0.34] day, P = .009). While there was no significant difference between 2 groups in 30-day complications (relative ratio [RR]: 0.92 [0.77–1.11], P = .38), the rate of thoracentesis (RR: 1.93 [0.63–5.88], P = .25) and the rate of chest tube placement (RR: 1.00 [0.37–2.70], P = .99). According to the sensitivity analysis, the relative impacts of the 2 groups had already stabilized. Subgroup analysis revealed that postoperative hospital stay was modified by Newcastle-Ottawa Scale score. The online GRADEpro Guideline Development Tool presented very low quality of evidence for the available data.

Conclusions:
This meta-analysis revealed that it is feasible and safe to remove a chest tube with high-output drainage after pulmonary resection for selected patients.