bluuebunny/crossref_metadata_2025_split huggingface dataset:
Disseminated Mycobacterium avium Complex Infection in a Patient Treated With Immunosuppressants
Authors: Ito Yuki , Watanabe Daisuke , Ikeda Sayaka , Okamoto Norihiro , Miyazaki Haruka , Tokunaga Eri , Ku Yuna , Ooi Makoto , Hoshi Namiko , Kodama Yuzo 
Published: April 2023

ABSTRACT

Mycobacterium avium complex (MAC) is an important cause of opportunistic infections in immunosuppressed hosts, such as patients with HIV infection and solid organ transplant recipients. MAC disease usually presents in 4 distinct clinical categories: chronic pulmonary disease, disseminated disease, skin/soft-tissue infection, and superficial lymphadenitis. However, clinical reports on gastrointestinal (GI) MAC disease are rare, especially in patients without HIV infection or a history of organ transplantation. We describe a case of non-HIV-associated GI MAC disease in a patient with long-term mycophenolate mofetil use. In this case, MAC organisms in the GI tract and ascites were observed. Endoscopy revealed a unique colonic image with large, deep epithelial denudations. This suggests that apart from patients with HIV infection or transplant recipients, those treated with immunosuppressants can have disseminated MAC. Therefore, internal physicians need to monitor patients undergoing mycophenolate mofetil immunosuppressant therapy.
A comprehensive review of non-alkaloidal metabolites from the subfamily Amaryllidoideae (Amaryllidaceae)
Authors: Ibrakaw Abobaker S. , Akinfenwa Akeem O. , Hussein Ahmed A. 
Published: April 2023

Abstract
Amaryllidoideae is a subfamily belonging to the Amaryllidaceae and is widely distributed in the southern hemisphere. The subfamily is well known for its content of pharmacologically active alkaloids and represents an important epicenter of Amaryllidaceae-alkaloid diversity. Other metabolites from Amaryllidoideae such as phenolics including flavonoids, lignans, chromones, and acetophenones, in addition to terpenoids and ceramides, have been reported and received less attention compared to alkaloids. Currently, 224 non-alkaloidal compounds have been isolated and identified from ∼7% of the subfamily members. Many of the isolated compounds showed interesting biological activities. Isolation of certain compounds such as flavans and phytosterols from Amaryllidoideae has significant taxonomical value among the Amaryllidaceae subfamilies. This article represents an extensive review of the non-alkaloidal chemical constituents of Amaryllidoideae and their biological activities including a brief discussion of their chemotaxonomical importance.
Heteropolyacid-loaded MOF-derived mesoporous zirconia catalyst for chemical degradation of rhodamine B
Authors: Wang Jialu , Yu Rongfei , Li Zhenying , Yang Fen , Luo Linmin , Wang Dandan , Cheng Huan , Zhang Yutao , Zhang Qiuyun 
Published: April 2023

Abstract
In this article, silicotungstic acid (STA)-loaded metal–organic framework (MOF)-derived composites (C-STA@ZrO2) were successfully synthesized by simple strategies. X-ray diffraction, Fourier transform infrared, scanning electron microscopy, energy-dispersive X-ray, N2 physisorption, UV-vis diffuse reflection spectroscopy, and X-ray photoelectron spectroscopy techniques were used to characterize the as-obtained composites. Intriguingly, C-STA@ZrO2 exhibits excellent photocatalytic performance, and rhodamine B (RhB) (40 mg·L−1) in water can be degraded to 93.9% after 120 min of irradiation. Moreover, various catalysts, catalyst dosage, and dye concentrations on RhB degradation were evaluated. Besides, the reusability of C-STA@ZrO2 was also investigated. This work may provide a new and significant guideline for exploring excellent performance of MOF-derived hybrid material for wastewater purification.
Visual representation of ASUU strikes in Nigeria: a semiotic analysis of cartoons in selected Nigerian newspapers
Authors: Makinde Peter Oyewole 
Published: April 2023

Abstract
Until recently, the study of language and meaning of cartoons, the media discourses they generate, and their analysis as a creative means of exploring meaning-making processes as semiotic resources have not received much scholarly attention in Nigeria. Although cartoons that involve the use of satire and humour as visual representations of reality have gained prominence across many media platforms in Nigeria, only a few scholars have examined this from a social semiotics perspective. This has created a gap in the literature, thus creating room for a paradigm shift in the field of social semiotics. This study explores the semiotics of cartoons in selected Nigerian newspapers to examine the meaning-making resources employed in the visual representation of ASUU strikes in Nigeria. The study, therefore, examines how cartoonists manipulate symbols, signs, and other semiotic resources to convey specific meanings through visual and textual representations. The study adopts a qualitative research design; data comprising cartoons sourced from selected Vanguard Newspapers and websites are analyzed using Kress and Van Leeuwen’s visual semiotics and interpreted from the standpoints of Halliday’s Systematic Functional Linguistics (SFL) approach and O’Halloran’s position on metaphorical constructions of meaning. Here, metaphorical manipulation and representation of visual elements in the selected cartoons are interrogated. Findings from the study show the use of semiotic resources in the portrayer of reality in the context of the seemingly intractable ASUU strikes and their consequences on academic activities in Nigeria. This scholarly intervention deserves attention as it significantly contributes to the field of social semiotics through its visual representation in portraying challenges faced by the educational systems in Nigeria vis-à-vis poor government funding.
Organic photoredox catalysts: tuning the operating mechanisms in the degradation of pollutants
Authors: Blázquez-Moraleja Alberto , Cabezuelo Oscar , Martinez-Haya Rebeca , Schmidt Luciana C. , Bosca Francisco , Marin Maria Luisa 
Published: April 2023

Abstract
Photocatalysis is an emerging area of chemistry that takes advantage of light as the primary source of energy to carry out chemical transformations. In this context, organic photocatalysts appear as an alternative that has proven to be efficient in treating polluted effluents. Although organic photocatalysts are not able to generate hydroxyl radical, their photoactivated excited states generated using visible light can act as strong oxidants in most cases. In fact, pollutant photooxidation can be produced from an initial electron transfer between an excited state of an organic photocatalyst and the contaminant, generating their respective radical anion and cation (Type I mechanism). However, as most of the organic photocatalysts are able to generate singlet oxygen, pollutant degradation can also be initiated from this oxidative species (Type II mechanism). Moreover, the heterogenization of the photocatalysts seems the straightforward step to boost photostability and facilitate recovery after the reaction. In the present review, we chronicle our research progress and how interestingly, it cannot be assumed that the main reaction pathways of a photocatalyst are the same under homogeneous conditions as in heterogeneous media. Herein we have selected Rose Bengal (RB), Riboflavin (RF), and a perylene diimide derivative (PDI) to illustrate the different modes of action of these organic photocatalysts under homogeneous/heterogeneous conditions.
Room temperature X-ray absorption spectroscopy of metalloenzymes with drop-on-demand sample delivery at XFELs
Authors: Bogacz Isabel , Makita Hiroki , Simon Philipp S. , Zhang Miao , Doyle Margaret D. , Chatterjee Ruchira , Fransson Thomas , Weninger Clemens , Fuller Franklin , Gee Leland , Sato Takahiro , Seaberg Matthew , Alonso-Mori Roberto , Bergmann Uwe , Yachandra Vittal K. , Kern Jan , Yano Junko 
Published: April 2023

Abstract
X-ray crystallography and X-ray spectroscopy using X-ray free electron lasers plays an important role in understanding the interplay of structural changes in the protein and the chemical changes at the metal active site of metalloenzymes through their catalytic cycles. As a part of such an effort, we report here our recent development of methods for X-ray absorption spectroscopy (XAS) at XFELs to study dilute biological samples, available in limited volumes. Our prime target is Photosystem II (PS II), a multi subunit membrane protein complex, that catalyzes the light-driven water oxidation reaction at the Mn4CaO5 cluster. This is an ideal system to investigate how to control multi-electron/proton chemistry, using the flexibility of metal redox states, in coordination with the protein and the water network. We describe the method that we have developed to collect XAS data using PS II samples with a Mn concentration of <1 mM, using a drop-on-demand sample delivery method.
A study of the distribution of classes of lexical aspect in Spanish by Chinese learners of Spanish in oral narration
Authors: Sun Yuliang , Rodríguez Lourdes Díaz 
Published: April 2023

Abstract
This paper aims to analyze the non-native use of Spanish verbs of different aspectual classes by Mandarin Chinese speakers performing oral narrative tasks. In this work, we adopt Vendler’s (Vendler, Zeno. 1967. Linguistics in philosophy. Ithaca: Cornell University Press) lexical-aspect classification (states, activities, accomplishments, and achievements), and we analyze the Spanish L2 acquisition of these categories by sinophones both at the level of the lexical form acquisition and at the semantic level. Based on data obtained from two oral narrative tasks elicited from storyboard vignettes performed by three groups of learners of L2/L3 Spanish (ranging from B1 to C1 levels of the CEFR), this work supports Jiang’s (Jiang, Nan. 2000. Lexical development and representation in a second language. Applied Linguistics 21(1). 47–77) L2 lexical acquisition pattern at the lexical form level, as our sinophone learners show a similar pattern to the one observed in native speakers in the use of aspectual class of compositional form (accomplishments)and aspectual classes of individual form (states, activities and achievements). However, at the lexical semantic level, we found that, besides L2 proficiency, the properties of lexical semantics may also impact learners’ L2 lexical processing.
Measurement of Fatigue Crack Growth in Compact Tension Specimen Using an Optical Extensometer
Authors: Zhang Shuiqiang , Zhu Qirui 
Published: April 2023

Abstract
In this investigation, fatigue crack growth (FCG) tests are performed on transformation induced plasticity steels to characterize the relevance of stress intensity and crack growth rates with standard compact tension (CT) specimens. An optical extensometer that can achieve real-time displacement measurement is developed based on digital image correlation. Instead of a displacement gauge, the optical extensometer is adopted in FCG tests to measure CT specimen crack opening displacement (COD). Compared with stress intensity, it is difficult to calculate crack growth rates with COD. Therefore, the compliance equation and incremental polynomial method are programmed with C++ languages to obtain the steady crack growth curve directly. The proposed method is verified with experimental results obtained by the displacement extensometer. In addition, the precision of the displacement measurement is assessed, and the error induced by displacement output rates is discussed.
Noradrenergic Input from Nucleus of the Solitary Tract Regulates Parabrachial Activity in Mice
Authors: Ji Yadong , Onwukwe Chimdiya , Smith Jesse , Laub Hanna , Posa Luca , Keller Asaf , Masri Radi , Cramer Nathan 
Published: April 2023

AbstractThe parabrachial complex (PB) is critically involved in aversive processes, and chronic pain is associated with amplified activity of PB neurons in rodent models of neuropathic pain. Here, we demonstrate that catecholaminergic input from the caudal nucleus of the solitary tract (cNTScat), a stress responsive region that integrates interoceptive and exteroceptive signals, causes amplification of PB activity and their sensory afferents. We used a virally mediated expression of a norepinephrine (NE) sensor, NE2h, fiber photometry, and extracellular recordings in anesthetized mice to show that noxious mechanical and thermal stimuli activate cNTS neurons. These stimuli also produce prolonged NE transients in PB that far outlast the noxious stimuli. Similar NE transients can be evoked by focal electrical stimulation of cNTS, a region that contains the noradrenergic A2 cell group that projects densely on PB.In vitro, optical stimulation of cNTScatterminals depolarized PB neurons and caused a prolonged increase the frequency of excitatory synaptic activity. A dual opsin approach showed that sensory afferents from the caudal spinal trigeminal nucleus are potentiated by cNTScatterminal activation. This potentiation was coupled with a decrease in the paired pulse ratio (PPR), consistent with an cNTScat-mediated increase in the probability of release at SpVc synapses. Together, these data suggest that A2 neurons of the cNTS generate long lasting NE transients in PB which increase excitability and potentiate responses of PB neurons to sensory inputs. These reveal a mechanism through which stressors from multiple modalities may potentiate the aversiveness of nociceptive stimuli.
Information Practices of University’s Civil Servants in Managing Family Archives for Asset Declarations
Authors: Farhah Rufaidah , Lawanda Ike Iswary 
Published: April 2023

PurposeThis study aims to elaborate on the information practices carried out by university’s civil servants in managing and preparing family archives for asset declaration purposes by applying a theory of everyday information practices. This study uses McKenzie’s two-dimensional model which consists of Active Seeking, Active Scanning, Non-directed Monitoring, and By Proxy modes, along with the Connecting and Interacting phases in each mode. MethodThis study is a descriptive qualitative study and utilizes the data analysis method. Research data was collected through semi-structured online interviews. The informants were selected based on purposive sampling. Results/FindingsThe results of this study indicate that only three modes of information practices were applied by the university’s civil servants for asset declaration purposes. The three modes are Active Seeking, Active Scanning, and By Proxy. ConclusionInformation practices for archive management are a part of daily life. It cannot be separated from context such as the type of archive and for what purpose. It is clear that archival study is related to information practices.
Journal Article Writing Assistance Program: An Effort to Improve Publication in Islamic University
Authors: Farkhan Muhammad , Rahma Awalia , Nisa Mauidlotun , Azwar Muhammad 
Published: April 2023

PurposeThis mixed-methods study aimed to explore how the Faculty of Humanities carried out Journal Article Writing Assistance Program (JAWAP) in 2021, and determine its contribution to the participants’ English articles. MethodThis mixed methods research used a convergent mixed methods design that relied on 17 participants’ perception towards its implementation as the main data collected using questionnaire, interview, and document analysis. The quantitative data were analyzed using correlational statistics and compared with qualitative data to confirm or dis-confirm each other. FindingsThe study revealed that JAWAP worked in an online scheme where the communication between the participants and reviewers did not occur intensively. The study identified weaknesses in the review process, such as the article’s compliance with the author guidelines, lack of interdisciplinary discussion and collaboration with others, and the deservedness to be published in internationally journals. However, the study shows the JAWAP contributed significantly to the participants’ English articles. ConclusionJAWAP as an assistance program can help the participants to write quality English articles. To increase its contribution to the English article quality, the faculty should conduct the program intensively during the writing process openly in an intensive communication between reviewers and participants in small groups.
What Residents Want: Perceptions of Learning During a Pediatrics Night Float Rotation
Authors: Torwekar Beth L. , Robinson Margaret , Durham Megan , Cooper Dawn , Wurster William , Bowen Judith L. 
Published: April 2023

OBJECTIVE
Most efforts to improve the educational value of night shifts focus on delivering content through structured sessions. Less is known about aligning curricular efforts with inherent nighttime learning. This study explored interns’ nighttime experiences to better understand how learning works for the purpose of designing a curriculum to best support interns’ learning at night.

METHODS
The authors employed a constructivist grounded theory approach. They conducted semistructured interviews with 12 Family Medicine and Pediatric interns recruited during their first-night float rotation at a tertiary care children’s hospital between February 2020 and August 2021. Interviews elicited stories about nighttime experiences on the basis of a modified critical incident technique. Four authors used an inductive approach to data analysis and codebook development, then all authors participated in a thematic review.

RESULTS
The authors identified distinctions between interns’ perceptions of teaching and learning, with participants reporting rich instances of experiential learning at night. The authors discovered that interns do not want a didactic teaching curriculum at night. Rather, they want support to optimize workplace learning: the opportunity to independently initiate patient assessments, informal teaching arising from patient care, reassurance that support from supervisors is readily available, orientation to resources, and feedback.

CONCLUSIONS
Findings suggest informal workplace learning is already occurring at night and historical attempts to implement formal curricula may have a low return on investment. A curricular frameshift is recommended to support learning at night that emphasizes informal teaching responsive to learning needs that arise from patient care, integrating but not emphasizing formal didactics when necessary.
A relação entre fobias específicas com ansiedade, impulsividade e depressão
Authors: Lemos Vasconcellos Silvio José , Rocha da Cas1 Andressa , Mossmann Ferreira Stephane , Schneider Juliana Thais , Bevilacqua Vedoin Carolina , Pereira Barbosa Thamires 
Published: April 2023

Uma fobia específica é um medo irreal ou extremo de uma situação, objeto ou ambiente específico. Teorias iniciais sobre aquisição de fobias específicas favoreceram uma explicação no condicionamento do medo. Este artigo quantificou medos com um potencial ofensivo maior e menor para as espécies em uma amostra de 148 estudantes com média de idade de 21,5 anos (DP = 2,6). Além das diferenças estatisticamente significantes entre as duas categorias de medo, houve uma correlação de medos de uma menor ofensa potencial para humanos com ansiedade e depressão, estresse e impulsividade. Este trabalho pode ajudar a elucidar problemas relacionados a incidência de certas fobias.
PELATIHAN KOMUNIKASI UNTUK MENINGKATKAN KERJASAMA ANTAR TIM PADA OSIM MAN 1 PESSEL
Authors: Juniartika Rifa , Saputri Meza 
Published: April 2023

Pelatihan merupakan hal yang sangat penting terutama mengembangkan sumber daya manusia di perusahaan, organisasi, instansi pendidikan ataupun lembaga lain untuk meningkatkan kualitas kinerja karyawan. Tujuan pelatihan ini adalah membantu peserta untuk memahami maksud dari kerjasama dan komunikasi serta implikasi kerjasama dan komunikasi di dalam organisasi, meningkatkan kesadaran diri peserta akan pentingnya kerjasama dan komunikasi antar tim, membantu peserta untuk memahami pentingnya komunikasi yang baik dari masing-masing anggota organisasi, membangun komunikasi antar anggota organisasi agar terciptanya efektivitas dalam bekerja sama dan membuat peserta mampu mengaplikasikan kemampuan bekerjasama dan komunikasi antar anggota di OSIS MAN 1 PESSEL. Sampel pada pelatihan ini berjumlah 12 orang. Metode pada pelatihan ini yaitu metode kuantitatif eksperimen dengan menggunakan metode awal penelitian wawancara, focus group discussion, dan observasi. Lalu metode pelatihannya menggunakan metode cognitive method, case study, dan action learning. Alat ukur yang digunakan adalah skala lembaran evaluasi reaksi kegiatan, skala peningkatan pengetahuan, dan skala evaluasi perilaku. Hasil pelatihan ini yaitu Pre-Test dan Post-Test dapat nilai signifikansi yang >0,05 maka ini menunjukkan bahwa test yang dilaksanakan berdistribusikan norma. Serta uji signifikan dari evaluasi pembelajaran ini menunjukkan <0,05 yang artinya juga bahwa pelatihan yang dilakukan begitu efektif, dan dapat disimpulkan bahwa modul kerjasama dan komunikasi yang telah diberikan dalam pelatihan ini dapat meningkatkan perilaku kerjasama dan komunikasi dari pribadi yang berada dalam OSIS MAN 1 PESSEL.Kata Kunci: Pelatihan Komunikasi, Meningkatkan Kerjasama
PELATIHAN PENGUATAN PENDIDIKAN KARAKTER SANTRI DI LINGKUNGAN PONDOK PESANTREN TAHFIDZ DI ERA DIGITAL
Authors: Salsabillah A. Aisyah , Zainuddin Zainuddin 
Published: April 2023

Pendidikan karakter menjadi alternatif dalam membangun karakter anak bangsa yang saat ini telah mengalami persoalan serius terutama di era digital saat ini. Adapun tujuan pelatihan penguatan pendidikan karakter adalah mempertahankan nilai-nilai karakter santri, yakni keikhlasan, kesederhanaan, kemandirian, persaudaraan yang kuat, dan mengamalkan amar ma’ruf nahi munkar yang berpedoman pada Al Qur’an dan Hadits. Pondok Pesantren ini merupakan Pondok Pesantren Tahfid. Santri sudah mempunyai bekal dalam mengamalkan perilaku kehidupan sesuai dengan Al-Qur’an dan sunnah. Berpedoman pada Al-Qur’an di era digital sekarang dapat membantu orang tua dalam pembentukan karakter masing-masing anak. Era digital sekarang ini memiliki pengaruh yang besar bagi karakter, pendidikan, serta perilaku anak di zaman sekarang. Pada saat ini, banyak remaja yang terjerumus keluar syari’at dikarenakan pergaulan bebas. Salah satunya adalah pemanfaatan telepon genggam, karena sudah seperti benda yang wajib dimiliki, tak terkecuali anak-anak di bawah umur yang bahkan belum bisa membaca ataupun menulis, mereka sudah mengenal yang namanya telepon genggam. Adapu salah satu kontribusi pembentukan karakter dalam pelatihan ini adalah mengajarkan kepada santri, tentang bagaimana cara mengunakan handphone dengan benar, membekali siswa terkait dengan kenakalan remaja saat ini dan juga untuk mengajarkan kepada anak anak cara untuk mengkaji dan mengamalkan Al-Qur’an dalam kehidupan sehari-hari. Salah satu bentuk pemanfaatan telepon genggam yang dilakukan pada pelatihan ini adalah sebagai sarana entrepreneur dan juga Al Qur’an yang menjadi pedoman dalam usaha. Santri bisa memanfaatkan fasilitas berbasis digital menjadi sesuatu yang lebih bermanfaat bagi hidupnya dan membangun jiwa Al Qur’an dalam hatinya.Kata Kunci: Pondok pesantren tahfidz, Era digital, Telepon genggam, Al-Qur’an, Entrepreneur