bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multi-Stage optimization under uncertainty in reverse logistics operations: An industrial scenario
Authors: Das Prasun , Ghosh Sayantan 
Published: June 2023

The major concern of reverse logistics operations involves reducing logistics costs, improving after sales service, waste disposal and providing good quality service in today's green environment. Process optimization involving uncertainty under reverse logistics set-up is a major challenge. There is a need to consider the dynamics of the real situation because of the variation of product/process characteristics to make the system more robust. A comparative analysis and the need for multi-stage optimization are illustrated here based on a single stage optimization model after performing its sensitivity analysis. Accordingly, a multi-stage optimization problem is formulated here to solve the cost optimization problem of charge mix under a reverse logistics set-up of a foundry business and to deal with the uncertainties involved in a practical business scenario. The proposed framework can be effectively implemented in a similar reverse logistics environment considering uncertainties of the process parameters/product characteristics.
Design of hybrid power system for COMSATS University Islamabad using homer pro software
Authors: Rashid Amir , Ehsan Muhammad , Rashid Javid 
Published: June 2023

More than a billion people do not have access o electricity, so it is important to find ways to generate power close to where they live. Hybrid energy systems can be made and used to generate electricity for homes and businesses that are not connected to national or regional power grids. Hybrid energy systems yield greater environmental and economic returns than stand-alone geothermal, solar, wind, or bigenerational systems. The goal of this paper is to simulate a hybrid power system for COMSATS University in Islamabad that is both technically and economically feasible and plays a big part to support clean energy production and safeguard the environment from toxic emissions. This paper provides a case study of COMSATS University Islamabad. The results showed that a hybrid system with a grid and a wind turbine that produced 1 MWh/yr was the best option. This study also provides a cost summary of PV panels, batteries, diesel generators, capital value, replacement, operation and maintenance (OM), fuel cost, and salvage value in dollars. In this study, a hybrid power system is designed that can provide us with a detailed analysis of power generation and consumption for the case study.
Characterisation of cementitious composite materials based on calcined clay activated by silicate from rice husk ash and Ingessil silicate - activator: sodium hydroxide (NaOH)
Authors: Nkotto Ludovic Ivan Ntom , Kamgang Gaëlle Dounbissi , Nkengue Lionel Pierre , Kanda Judicaël Sandjong , Metekong Jordan Valdès Sontia 
Published: June 2023

The ever-increasing cost of cement and its production of harmful carbone dioxide (CO2) has led development actors to continuously search for less environmentally polluting and low-cost binders. Hence the interest in the valorisation of agricultural resources through the production of different binders such as silicate for the elaboration of geopolymers at low manufacturing temperatures (<100 °C). In this study, Ingessil industrial silicate and rice husk ash silicate were used as pozzolan raw materials to prepare geopolymers with sodium hydroxide as activator at a concentration of 12 M. Two types of samples were developed: geopolymer mortars based on Ingessil silicate and geopolymer concretes based on Ingessil industrial silicate and rice husk ash silicate. Sand and gravel were used as fine and coarse aggregates for the production of geopolymer concretes. They were represented 80% of the mass of the geopolymer concretes according to the standards of elaboration.The porosity values obtained were of the order of 30%, i.e. water absorption values of about 18%, apparent specific weight of about 5% and bulk density of 1.7%. The mechanical values of BGAC-RHA samples are higher than those of BGAC-I. The physico-chemical properties of geopolymer mortars and concretes were similar.
Comparative bioactive compounds and antifungal potential evaluation of Mentha longifolia (L.) Hudson (Lamiaceae) extracts against plant pathogenic fungi
Authors: Ali Javid , Abbas Javed 
Published: June 2023

The present study was design to evaluate the Mentha longifolia stem, flower and leaves infusion, decoction and hydroalcoholic extracts to determine the bioactive molecules and antifungal activities by zone of inhibition technique, Minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) were assay by broth dilution technique and spore germination assay using Light Compound Microscope against plant pathogenic fungi (Fusarium oxysporum, Aspergillus parasiticus, Rhizoctonia solani and Alternaria alternata). The Mentha longifolia phytochemicals were found in the range flavonoids 3.8 - 2.4%, saponins were 5.6-3.4%, alkaloids 0.7-0.1% and total phenolic were 40-15 mg Gallic acid/g. The maximum zone of inhibition 23±1 mm and 22±1 mm were found by hydroalcoholic leaves extract against Fusarium oxysporum and Aspergillus parasiticus respectively. The MIC range of hydroalcoholic were 12.5-100 mg/mL, infusion were 25-100 mg/mL and decoction were 25-200 mg/mL. While MFC range of hydroalcoholic were 25-200 mg/mL, infusion were 50- 200 mg/mL and decoction were 50-200 mg/mL. Spore germination assay reaveled that increse in the extract concenetration decrese the spore germination. The results revealed that Mentha longifolia chemical composition might be build up as latent bio- fungicides against plant pathogenic fungi.
Geophysical assessment of groundwater contaminations from leachate intrusion in Amoyo dumpsite
Authors: Olatunji S. , Fauzan A.O. 
Published: June 2023

The work aims to map the extent of leachate intrusion in near-surface rocks around a reclaimed dumpsite (40 years old) in Amoyo town. Sixteen very low- frequency electromagnetic (VLF - EM) profiles were distributed in the four cardinal directions around the site. Twenty-nine (29) points were sounded, using Schlumberger approach, at all identified VLF anomalous points. The analyzed VLF-EM data revealed the presence of conductive pollutants (leachate plumes) at the subsurface. The geo-electric sections generated from the processed VES data supported the VLF-EM results. It is concluded that (i) leachate is still present in the rock formation of the reclaimed dumpsite several years after the abandonment and excavation of the waste materials (ii) the shallow aquifer is at risk of contamination (iii) the low resistivity of the basement rocks signified presence of leachates.
Monitoring the maturity of Ahmeur Bouamer Autochtonous variety and determining of the optimum harvest date
Authors: Ghouila Z. , Baaliouamer A. 
Published: June 2023

Morphological ampelography characteristics, technological, phenolic and tannic maturities were studied over four seasons (from 2009 to 2012) of Ahmeur Bouamer autochtonous Algerian variety. During the four harvests, Ahmeur Bouamer's cluster has showed a high quality of morphological parameters (weight, size, number of seeds/ berries per cluster).The weight was proportional to the size of the cluster which was moderately compact, thus avoiding the deformation and the bursting of the berries. As For the maturity index (MI), Ahmeur Bouamer grape recorded values ranging from 31.07 to 54.95 for the four seasons; values which would make it possible to consider that the harvest would be of excellent quality (when 30 <MI <50). As well as for total anthocyanin potential (TAP) exceeding 1000 mg / L and total polyphenol index (TPI) with values greater than 50, these values confirm that the cluster presents high level of maturity. The monitoring of the MI every week in the phase of ripening (september-october) for 2010 and 2011 have showed that the maximum ripeness index was reached on September 27th with highest level of maturity for both harvests, date that can be considered by the winemaker as optimal date of harvest.
Integration of remote sensing and geophysical methods for structural and lithological mapping in a part of Precambrian Basement Rocks, northern Nigeria
Authors: Olatunji S. 
Published: June 2023

Landsat 8 OLI data, Aeromagnetic data, and Radial Vertical Electrical Sounding (RVES) survey data were integrated to map lithology, delineate structures and their trends, and delineate possible mineralized zones in the area. Landsat 8 OLI data yielded a color composite image, and surface lineaments map of the area. The aeromagnetic maps were utilized to map lithology, and subsurface structures. A radial survey confirmed the fractures derived from the structural maps. Results classified the area into three geological units viz: migmatite, banded gneiss, and quartzite. The banded gneiss is the most deformed and contains series of structures that are significant for mineral and groundwater explorations. Clay alteration is the most dominant in the area, followed by iron oxide alterations. Lineament alignments are N-S, NNW-SSE, NNE-SSW, NE-SW, and E-W directions.
Fetal distress and the levels of malondialdehyde (MDA): A meta-analysis
Authors: Liu Yongli , Chi Xiuping , Qiang Zhe 
Published: June 2023

Purpose: To estimate the effect of malondialdehyde (MDA) level on fetal distress.
Methods: Meta-analyses of randomized controlled interventions were performed by searching 8 electronic databases (CNKI, VIP, CBM, WANFANG, Embase, PubMed, Cochrane, and Web of Science) from 1980 – to date for randomized controlled trials to determine any intrapartum fetal distress. A metaanalysis within a frequentist framework was performed and the quality and inconsistency of the trials were assessed. Dual selection and data abstraction were conducted. The methodological quality of the meta-analyses was assessed using AMSTAR, and the quality of evidence was assessed using GRADE. Random-effect models were used to pool results from individual studies included in each meta-analysis.
Results: A total of 1720 patients received MDA tests, and the results showed that MDA value of experimental group was 1.66 higher than that of control group. Heterogeneity between the two groups was high, suggesting that the choice of blood source significantly affected the result of meta-analysis (p < 0.05). The group of blood samples collected from mothers was highly heterogeneous, and combined with the results of 16 groups, the effective amount reached (2.08) was significant (z = 4.29, p < 0.05). This means that MDA increase in maternal blood during maternal-fetal distress. Secondly, cord blood samples were highly heterogeneous in the collection group, and the random effect was insignificant (z = 0.94, p > 0.05).
Conclusion: Malondialdehyde level in maternal and cord blood reflects the relationship between fetal distress and adverse outcomes. Further research is needed to confirm the extent to which they are related.
Elemene inhibits the growth and promotes apoptosis of bladder cancer cells through PTEN-Akt signaling pathway
Authors: Pei Yuhan , He Yuying , Geng Shen , Tang Cai , Dai Jiaxin , Ji Zhenshuai , Xie Cheng , Zhi Yunlai , Cai Chengkuan , Sun Fanghu 
Published: June 2023

Purpose: To investigate the influence of elemene on growth and apoptotic changes in bladder cancer cells, and the involvement of the phosphatase and tensin homologous protein (PTEN)-serine/threonine kinase (Akt) signal pathway in the process.
Methods: Human bladder cell line SV-HUC-1 and human bladder cancer cell line T24 were randomly assigned to blank control group and elemene groups. Protein expression levels of apoptosis-related factors (Bcl-2, Bax, and caspase-3] and PTEN, Akt, and p-Akt in both cells were determined using western blot assay.
Results: In T24 cells, the protein level of Bcl-2 was significantly higher in elemene group than in blank control, while the protein expression levels of Bax and caspase-3 in elemene group were significantly lower than the corresponding levels in blank control group (p < 0.05). The protein expression of PTEN level in T24 cells was significantly higher in elemene group than in blank control group, while protein expression level of p-Akt was significantly lower in elemene group than in blank control (p < 0.05). The Akt protein expression was comparable in elemene and blank control groups.
Conclusion: Elemene inhibits the growth and enhances apoptosis of bladder cancer cells through a mechanism involving up-regulation of the expression of PTEN and suppression of the expression of pAkt.
Knockdown of VAMP8 attenuates atherosclerosis and enhances the effect of simvastatin in APOE-deficient mice
Authors: Zhan Lei , Zhao Hua 
Published: June 2023

Purpose: To investigate the regulatory effects of vesicle-associated membrane protein 8 (VAMP8) in atherosclerosis (AS).
Methods: VAMP8 expression was assessed using quantitative real time-polymerase chain reaction (qRT-PCR) and western blot, while H&E staining was used to examine the morphology of arterial glandular tissues in AS mice. Lipid accumulation in mice was determined with the aid of Oil Red O staining, whereas the apoptosis of aortic cells was evaluated by TUNEL assay.
Results: VAMP8 was highly expressed in the advanced-stage AS samples, and was also elevated in AS mice (p < 0.01). VAMP8 protein level rose in AS mice (p < 0.01). Moreover, the aorta showed atherosclerotic lesions with intima thickening and atherosclerotic plaques in AS group (p < 0.01). However, these changes were alleviated in VAMP8-silenced group (p < 0.01). VAMP8 silencing decreased lipid accumulation and alleviated inflammation and oxidative stress in AS mice (p < 0.01). It was observed that depletion of VAMP8 reduced aortic cell apoptosis in AS mice (p < 0.05). Furthermore, VAMP8 knockdown enhanced the effect of simvastatin on atherosclerosis (p < 0.01).
Conclusion: Knockdown of VAMP8 alleviates AS in ApoE-deficient mice. This finding suggests that this might be a potential strategy for the prevention and treatment of AS.
HUBUNGAN TEKANAN DARAH DANN KREATININ SERUM PADA ANGGOTA GYMNASTIK DI PUSAT KEBUGARAN KOTA KENDARI
Authors: Balaka Kemal Idris , Annisaa Nur 
Published: June 2023

ABSTRACT
Creatinine is the end product of muscle creatine metabolism, synthesized in the liver, and is found in skeletal muscle, blood, and excreted in the urine. Blood pressure is a condition that describes a person's health condition. High blood pressure can be the cause of various health problems, such as heart failure, stroke, and kidney disorders. Several factors that affect creatinine levels in the blood include lifestyle such as excessive physical activity, age, habits of consuming energy drinks and lack of drinking water are trigger factors, so it is suspected that there is a correlation between blood pressure and serum creatinine. Type of research used is observational analytic, namely research that looks for variable relationships to determine whether there is a relationship between variables to be studied and then to obtain results, statistical analysis is carried out. The correlation test used is non-parametric correlation with Chi-Squareto see the correlation between blood pressure and serum creatinine, and the samples used were gymnastics members as many 30 people taken by random sampling method. The test results found that there was a relationship between blood pressure and serum creatinine, with a low significance level of 0.036 (contingency coefficient value).
Keywords: Blood pressure, creatinine, correlation, gymnastic member.
ABSTRAK
Kreatinin merupakan produk akhir dari metabolisme kreatin otot disintesis dalam hati, dan ditemukan dalam otot rangka, darah, dan dieksresikan dalam urin. Tekanan darah adalah suatu keadaan yang menggambarkan kondisi kesehatan seseorang. Tekanan darah yang tinggi dapat menjadi penyebab munculnya berbagai masalah kesehatan, seperti gagal jantung, stroke, dan gangguan pada ginjal. Beberapa faktor yang mempengaruhi kadar kreatinin dalam darah diantaranya ialah gaya hidup seperti aktivitas fisik berlebihan, usia, kebiasan mengonsumsi minuman berenergi dan kurangnya minum air putih menjadi faktor pemicu, sehingga di duga ada korelasi antara tekanan darah dan kreatinin serum. Jenis penelitian yang digunakan adalah observasional analitik yaitu penelitian yang mencari hubungan variabel untuk menentukan ada tidaknya hubungan antar variabel yang akan diteliti kemudian untuk memperoleh hasil dilakukan analisis statistik. Uji korelasi yang digunakan ialah korelasi non parametrik dengan Chi-Square untuk melihat korelasi antara tekanan darah dengan kreatinin serum. Sampel yang digunakan ialah anggota gymnastik sebanyak 30 orang yang diambil dengan metode random sampling. Hasil uji di dapatkan bahwa terdapat hubungan antara tekanan darah dan kreatinin serum, dengan tingkat signifikansi yang rendah yaitu sebesar 0.036 (nilai contingency coefficient).
Kata kunci: Tekanan darah, kreatinin, Anggota Gymnastik.
UJI DAYA HAMBAT EKSTRAK ETANOL BINTANG LAUT BERTANDUK (Protoreaster nodosus) TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus
Authors: Fauziah Yulianti , Wulaisfan Randa 
Published: June 2023

ABSTRAK
Bintang laut bertanduk merupakan salah satu biota laut yang digunakan sebagai obat tradisional. Salah satunya adalah pengobatan infeksi. Infeksi merupakan salah satu penyebab penyakit yang sering terjadi di daerah yang beriklim tropis khususnya Indonesia. Salah satu infeksi yang sering terjadi adalah infeksi pada kulit yang disebabkan oleh bakteri Staphylococcus aureus. Penelitian ini bertujuan untuk mengetahui apakah ekstrak etanol bintang laut bertanduk dapat menghambat pertumbuhan bakteri Staphylococcus aureus.
Jenis penelitian yang digunakan dalam penelitian ini adalah penelitian eksperimental yang terdiri atas lima perlakuan dan tiga kali pengulangan dengan menggunakan metode pengujian paper disk. Sampel uji yang diteliti adalah bintang laut bertanduk (Protoreaster nodosus) yang dilarutkan dalam DMSO 10% hingga didapatkan varian konsentrasi 5%, 10%, dan15% kemudian dilakukan uji daya hambat terhadap bakteri Staphylococcus aureus.
Hasil penelitian menunjukkan bahwa ekstrak bintang laut bertanduk menghambat pertumbuhan bakteri Staphylococcus aureus masing-masing konsentrasi 5%, 10% dan 15% yakni 5,99mm, 6,69mm dan7,64mm. Berdasarkan hasil tersebut dapat disimpulkan bahwa ekstrak etanol bintang laut bertanduk (Protoreaster nodosus) dapat menghambat pertumbuhan bakteri Staphylococcus aureus secara signifikan.
Kata kunci :Zonahambat, Bintang Laut Bertanduk, Staphylococcus aureus.
ABSTRACT
Horned starfish are one of the marine biota used as traditional medicine. One of them is the treatment of infections. Infection is one of the causes of diseases that often occur in the tropics, especially Indonesia. One infection that often occurs is an infection of the skin caused by Staphylococcus aureus. This study aims to determine whether the horned starfish ethanol extract can inhibit the growth of Staphylococcus aureus bacteria. This type of research used in this study is an experimental study consisting of five treatments and three repetitions using a diskette testing method. The test sample studied was a horned starfish (Protoreasternodosus) dissolved in DMSO 10% to 5%, 10%, and 15% of the variant of concentration was obtained then the inhibitory test was performed on Staphylococcus aureus bacteria. The results showed that the horned starfish extract inhibited the growth of Staphylococcus aureus, each concentrations of 5%, 10% and 15% respectively 5.99 mm, 6.69 mm and 7.64 mm. Based on these results it can be concluded that the ethanol extract of the horned starfish (Protoreasternodosus) can significantly inhibit the growth of Staphylococcus aureus bacteria.
Keywords: Inhibited zone, Horn Star, Staphylococcus aureus.
UJI EFEKTIVITAS EKSTRAK DAUN TEMBELEKAN (Lantana camara Linn) DALAM BENTUK GRANUL PADA BUNGA PINK TERHADAP KEMATIAN LARVA Aedes SP
Authors: Apriyanto Apriyanto , Balaka Kemal Idris , Zulkarnain Riska Amelia 
Published: June 2023

Dengue Hemorrhagic Fever (DHF) is a public health problem that appears mostly in the tropics and subtropics in the world. DHF including acute diseases caused by viral infections under the mosquitoes of Aedes aegypti and Aedes Albopictus. In Tembelekan leaves (Lantana camara Linn) contain active compounds namely flavonoids, alkaloids, saponins and tannins which can inhibit the development of mosquitoes and larvae. The purpose of this study was to determine the results of the effectiveness of the extract of the Tembelekan leaf (Lantana camara Linn) in the form of granules as larvicide against the death of larvae of Aedes sp. This research was conducted experimentally with variations in the concentration of 7%, 8%, 9%. 220 Aedes sp larvae were used, divided into 3 concentrations of granules simplicia of the Tembelekan leaves, 7%, 8%, and 9% with 3 repetitions. Abate 1% is used as a positive control. Each concentration contains 20 larvae in 100 mL of water. Observations were made by counting the number of dead larvae. The results of the study showed that the total mortality of larvae using granules simplicia Tembelekan leaves (Lantana camara Linn) at a concentration of 7% by (26%), concentration of 8% as big (53%) at a concentration of 9% by (81%)
Keywords: larvae of Aedes sp, Leaves tembelekan, Larvasida
Developing Task Persistence Skills in College Students with Hard of Hearing Using Strategic Content Learning
Authors: Onyishi Charity Neejide 
Published: June 2023

Poor task persistence is a major inhibitor of effective learning among students with hearing impairment. This study investigated the effect of strategic content learning (SCL) on poor task persistence of students with hearing loss in Nigeria. The study adopted a pretest-posttest control group design. A total of 117 participants from four special schools for hearing impaired in South-East Nigeria completed a task persistence scale at pre-treatment, post-treatment, and follow-up. Intervention was carried out for nine weeks using strategic content learning program manual. Data collected were analyzed using repeated-measures analysis of variance, chi-square, and t-test. Results revealed that task persistence of hearing impaired college students of SCL group were significantly improved compared to those in waitlist control group at the end of the intervention. Follow-up tests conducted after three months and six months revealed that the significant improvement in task persistence of participants in the experimental group was sustained. Result of the current study show that SCL is an effective strategy straining approach that can improve students’ task persistence in different areas of learning. Further studies could be conducted in Nigeria and other countries to investigate the efficacy of SCL in improving self-efficacy and volition among diverse populations of students.