bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pulmonary artery aneurysm
Authors: Bhattacharya Deepanjan , Sasikumar Deepa , Anoop Ayyappan , Valakada Jineesh , Naik Nitin , Dharan Baiju Sasi 
Published: February 2023

ABSTRACT
An 11-year-old girl presented with chronic cough and recurrent hemoptysis. On examination, she had features of right heart failure and cyanosis, with severe pulmonary hypertension on echocardiogram. Computed tomography pulmonary angiography showed aneurysmal dilatations of the pulmonary artery with elevated erythrocyte sedimentation rate and C-reactive protein and positive human leukocyte antigen B51. A diagnosis of Hughes–Stovin syndrome (vascular variant of Behcet's syndrome) was confirmed, and she was started on immunosuppression, on which there was improvement.
Sinoatrial nodal disease presenting with tachy-bradycardia syndrome in a fetus of anti-SSA/SSB-positive mother
Authors: Karmegaraj Balaganesh 
Published: February 2023

ABSTRACT
Tachy-bradycardia syndrome (TBS) has been reported rarely in the fetus. We present here an unusual dominant involvement of sinoatrial node in a fetus presenting with TBS of anti-Sjögren'syndrome-related antigen A (SS-A) and antigen B (SS-B) autoantibodies positive mother. Prenatal imaging findings, Doppler hemodynamics, and outcomes are described.
Effects of Different Regimens of Insulin on Body Mass Index Commonly Used in Type 2 Diabetes Mellitus
Authors: Islam Tazin , Das Adhir Kumar , Rahaman Md. Arifur , Nahar Sharifun , Jahan Quazi Alifa , Ansari M A Jalil , Prasad Indrajit , Saifuddin Mohammad , Islam Moinul , Sharifuzzaman Mirza 
Published: February 2023

Background:
Weight gain is an ongoing challenge when initiating insulin therapy in patients with Type 2 diabetes mellitus. The aim of this study is to observe and compare the effect of commonly used regimens of insulin on body mass index (BMI) among Type 2 diabetes patients.

Methods:
An observational study was conducted in two diabetic centers in Dhaka starting from July 2018 to June 2019. During the 12 weeks of the data collection period, a total of 100 patients were included according to selection criteria and then divided into two equal groups. Patients who were prescribed with premixed (conventional or analog) 30/70 insulin twice daily with or without oral Antidiabetic drugs were included in Group I (n = 50) and the patients who were prescribed with insulin glargine once daily with a bolus insulin (conventional or analog) three times before large meals with or without oral Antidiabetic drugs were included in Group II (n = 50). BMI was calculated from the height and weight of the patients initially as baseline data and again after 12 weeks of treatment in both groups. Fiber Bragg grating, 2 h ABF, and hemoglobin A1C (HbA1c) change were also observed among the patients of both insulin groups from diagnostic reports during the study period.

Results:
After 12 weeks of treatment, mean body weight (±standard deviation [SD]) was increased significantly from 59.82 ± 12.33 kg to 60.40 ± 13.38 kg in Group I (P = 0.01) and from 59.00 ± 12.36 kg to 60.33 ± 12.97 kg in Group II (P = 0.02). Mean BMI (±SD) increased significantly from 23.71 ± 4.69 kg/m2 to 24.10 ± 4.17 kg/m2 in Group I (P = 0.01) and from 24.00 ± 4.30 kg/m2 to 24.43 ± 4.59 kg/m2 in Group II (P = 0.02) during the study period. The mean BMI compared between two study groups (24.10 ± 4.17 vs. 24.43 ± 4.59) kg/m2 m+ after 12 weeks of treatment was not statistically significant (P = 0.816). About 64.0% of patients in Group I and 68.0% in Group II have shown weight gain and BMI change after 12 weeks. Mean HbA1c (±standard deviation [SD]) reduced significantly from 10.40% ± 2.17% to 7.76% ± 1.41% in Group I and from 10.41% ± 1.80% to 7.63% ± 1.37% in Group II. About 48.0% of patients in Group I and 56.0% of patients in Group II achieved glycemic target <7%. About 28.0% of patients in Group I and 20.0% of patients in Group II had hypoglycemia.

Conclusion:
From the current study, it can be concluded that both insulin regimens significantly cause weight gain, BMI change and also significantly effective in glycemic control. However, in comparison between the two groups, there was no significant difference. Hence, both premixed and glargine-based basal-bolus regimen can be prescribed as per patient need. This result may provide some preliminary information for further investigation
Validation of Deauville Score for Response Evaluation in Hodgkin's Lymphoma
Authors: John Junita Rachel , Oommen Regi , Hephzibah Julie , Mathew David , Korula Anu , Shanthly Nylla , Eapen Anu 
Published: February 2023

Context:
Positron emission tomography (PET) using F-18 fluorodeoxyglucose (FDG) for treatment monitoring in patients with lymphoma is one of the most well-developed clinical applications. Deauville five-point score (DS) is recommended for response assessment in international guidelines. DS gives the threshold for adequate or inadequate response to be adapted according to the clinical context or research question.

Aims:
We aimed to validate DS in Hodgkin's lymphoma (HL) by retrospectively assigning this score to F-18 FDG PET-computed tomography (CT) studies done before 2016 and analyzing its concordance with the line of management. The secondary aim was to assess the reproducibility of DS in the interpretation of PET-CT scans.

Subjects and Methods:
A total of 100 eligible consecutive patients underwent F-18 FDG PET-CT scans between January 2014 and December 2015. Their interim, end of treatment, and follow-up PET scans were retrospectively visually analyzed and assigned DS by three nuclear medicine physicians. Concordance was defined as agreement between the DS assigned and the line of treatment. Interobserver variability was calculated using weighted Kappa and presented with 95% confidence interval.

Results:
Among 212 scans assigned DS, 165 scans showed agreement between the DS and line of treatment. Of these, 95.2% of scans scored DS 1–3 were kept on following or the same treatment plan was continued and patients did well. Among the scans that showed discordance, 24 scans scored DS 4/5 were continued on the same treatment regimen and the next assessment showed disease progression.

Conclusions:
Our study confirmed that DS is a useful tool to aid in reporting F-18 FDG PET-CT in the management of HL with good positive and negative predictive values. This study also demonstrated good interobserver agreement.
99m-Tc MDP Bone Scan Image Enhancement using Pipeline Application of Dynamic Stochastic Resonance Algorithm and Block-Matching 3D Filter
Authors: Pandey Anil Kumar , Kaur Gagandeep , Chaudhary Jagrati , Hemrom Angel , Jaleel Jasim , Sharma Param Dev , Patel Chetan , Kumar Rakesh 
Published: February 2023

Introduction:
In this pilot study, we have proposed and evaluated pipelined application of the dynamic stochastic resonance (DSR) algorithm and block-matching 3D (BM3D) filter for the enhancement of nuclear medicine images. The enhanced images out of the pipeline were compared with the corresponding enhanced images obtained using individual applications of DSR and BM3D algorithm.

Materials and Methods:
Twenty 99m-Tc MDP bone scan images acquired on SymbiaT6 SPECT/CT gamma camera system fitted with low-energy high-resolution collimators were exported in DICOM format to a personal computer and converted into PNG format. These PNG images were processed using the proposed algorithm in MATLAB. Two nuclear medicine physicians visually compared each input and its corresponding three enhanced images to select the best-enhanced image. The image quality metrics (Brightness, Global
Contrast
Factor (GCF), Contrast
per
pixel (CPP), and Blur) were used to assess the image quality objectively. The Wilcoxon signed test was applied to find a statistically significant difference in Brightness, GCF,
CPP,
and
Blur of enhanced and its input images at a level of significance.

Results:
Images enhanced using the pipelined application of SR and BM3D were selected as the best images by both nuclear medicine physicians. Based on Brightness, Global Contrast Factor (GCF), CPP, and Blur, the image quality of our proposed pipeline was significantly better than enhanced images obtained using individual applications of DSR and BM3D algorithm. The proposed method was found to be very successful in enhancing details in the low count region of input images. The enhanced images were bright, smooth, and had better target-to-background ratio compared to input images.

Conclusion:
The pipelined application of DSR and BM3D algorithm produced enhancement in nuclear medicine images having following characteristics: bright, smooth, better target-to-background ratio, and improved visibility of details in the low count regions of the input image, as compared to individual enhancements by application of DSR or BM3D algorithm.
Study of Coverage and Barriers of Immunisation Among Children of Age 12–23 Months in Urban Areas of Rishikesh
Authors: Asha T. J. , Singh Mahendra , Aggarwal Pradeep , Sharma Nandita , Narayanan Ajun Unnikochan , Anjali M. , Namitha R. S. 
Published: February 2023

Background:
Ensuring high immunisation coverage and its acceptance among the beneficiaries are crucial for a healthy society. Hence, this study aimed to estimate vaccine coverage and barriers of immunisation among children of age 12–23 months in urban areas of Rishikesh, Uttarakhand.

Aims:
To estimate the immunization coverage rate among children of age 12-23 months in urban area of Rishikesh.

Objectives:
To identify the barriers towards immunization in children of age 12-23 months in urban area of Rishikesh.

Materials and Methods:
A community-based cross-sectional study was done in urban areas of Rishikesh for 1 year, including 210 children, using the WHO's 30 × 7 cluster sampling technique to collect data on immunisation status.

Results:
About 92% of the children were fully immunised. Bacillus Calmette–Guérin has the highest coverage rate (99.5%), whereas the coverage was the lowest for the measles vaccine (93.8%). Full immunisation coverage was found to be statistically significant with the education of the respondent, socio-economic status (SES) of the family and birth order of the child. Additional vaccines uptake showed a significant association between SES of the family and the place of vaccination.

Conclusion:
There were significant variations in childhood immunisation coverage across socio-economic and demographic factors. These findings emphasize on the need for regular monitoring and evaluation of immunisation coverage to achieve the benefits of vaccination in all strata of society.
The Role of the Pro-Inflammatory Cytokine Interferon-Gamma in Type 2 Diabetes and Its Correlation with Atherosclerosis
Authors: Jasim Al-Tamimi Marwa Naeem , Al-Shawk Refif Sabih , Al-Karawi Isam Noori Salman 
Published: February 2023

Background:
Immunity plays a major role in the development of atherosclerosis in type 2 diabetes mellitus (T2DM). Pro-inflammatory cytokines, such as interferon gamma (IFN-γ), play an important role in atherosclerosis-related inflammation.

Aims:
This study aims to determine whether IFN-γ level and AIP in patients with T2DM are associated with atherosclerosis development and the effect of IFN-γ concentration level in disease progression.

Materials and Methods:
This study involved 60 Iraqi T2DM patients (30 with dyslipidemia and 30 without dyslipidemia) with an age range of 35–70 years. For the purpose of comparison, 22 healthy participants comparable for T2DM were included in the study.

Results:
this study shows a significant increase in IFN-γ level in the patient groups as compared to the control group (P < 0.009). There was a gradualincrease of AIP in the three studied groups with a significant difference (P < 0.001). Conclusion: The level of IFN-γ and the AIPmay reflect the progression atherosclerosis which may give an alarming sign in studying group patients.
Subtle but Pervasive; the Impact of Stakeholders Interest on Radio Programing Diversity in Kenya
Authors: Wekesa Allan , Mberia Hellen , Omoke Lilian 
Published: February 2023

Purpose: Radio stations in Kenya are confronted with financial problems due to the business model still grounded on advertising. The advertiser as a major stakeholder has potential influence over any medium which seeks his patronage, through his control of the purse strings. People listen to the radio for the programmes rather than advertisements and radio advertisements are not heard in isolation, but generally appear within the context of programmes. The subtle pressures on media enterprises by advertisers lead to the assumption that decisions concerning radio programming are much more frequently taken under the influence of economic principles shaped by the advertising industry and not under the perspective of journalistic news values. The study was anchored on the political economy of the media theory
Methodology: The study adopted a mixed research design method, data was gathered through questionnaires and interviews and analysed using descriptive and inferential statistics.
Findings: The study established that there was a statistically significant positive relationship between stakeholders and radio programming diversity. The study found that through his control of the purse strings, the advertiser as a stakeholder has potential influence over radio programming decisions.
Unique Contribution to Theory, Practice and Policy: The empirical findings contribute to our understanding of the subtle influence of the advertisers on radio programming decisions due to their ability to withhold sponsorship. The study also contributes to our understanding of the question of how media organizations specifically radio are funded.
TÌNH TRẠNG NHIỄM KHUẨN TIẾT NIỆU VÀ KHÁNG KHÁNG SINH TẠI BỆNH VIỆN ĐA KHOA TỈNH KIÊN GIANG NĂM 2021
Authors: Trần Quốc Huy , Trần Thị Mộng Lành , Lý Ngọc Trâm , Lê Văn Chương , Trần Duy Thảo 
Published: February 2023

Đặt vấn đề: Nhiễm khuẩn đường tiết niệu là một trong những bệnh truyền nhiễm do vi khuẩn, chiếm tỉ lệ mắc bệnh cao đáng kể trong các trường hợp nhiễm khuẩn tại bệnh viện. Việc giám sát phát hiện sớm và ngăn ngừa NKTN là rất quan trọng đối với bác sĩ lâm sàng giúp chẩn đoán và điều trị hiệu quả. Mục tiêu: Khảo sát vi khuẩn gây nhiễm trùng đường tiết niệu, xác định mức độ kháng kháng sinh của từng chủng vi khuẩn phân lập được. Phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang những bệnh nhân nội trú có chẩn đoán lâm sàng là nhiễm khuẩn đường tiết niệu, được chỉ định cấy nước tiểu cho kết quả dương tính (>100.000 vi khuẩn/mL) và thực hiện kháng sinh đồ. Kết quả: E. coli có tỉ lệ cao nhất 54,5%, kế đến là K. pneumoniae 15,6%, Pseudomonas spp 9,9%, Enterococcus faecalis 6,0%. Về tỉ lệ đề kháng kháng sinh E. coli có tỉ lệ để kháng cao với Cefazolin (100%), Ampicillin (97,9%), Ciprofloxacin (91,7%). K. pneumoniae đề kháng với Ampicillin, Cefazolin khá cao (100%), Ciprofloxacin (96,4%), Ampicillin/sulbactam (92,7%), Ceftazidime (90,9%). Pseudomonas spp có tỉ lệ đề kháng với Nitrofurantoin cao (91,2%), Ceftazidime, Ciprofloxacin (88,6%), Meropenem (85,7%). Enterococcus faecalis đề kháng với Tetracycline (81,0%), Levofloxacin (71,4%) và chưa phát hiện đề kháng với Vancomycin, Nitrofurantoin, Linezolid. Staphylococcus spp tỉ lệ đề kháng kháng sinh với Ampicillin, Penicillin G (100%), Gentamicin (90%), Oxacillin (80%), Ciprofloxacin (70%), chưa phát hiện sự đề kháng đối với Nitrofurantoin, Vancomycin. Kết luận: E. coli là vi khuẩn gây nhiễm khuẩn đường tiết niệu cao nhất. Tình trạng đề kháng kháng sinh của các loại vi khuẩn ngày càng cao trong bệnh viện.
THAY ĐỔI LÂM SÀNG TRÊN BỆNH NHÂN CẮN NGƯỢC VÙNG CỬA TRONG ĐỘ TUỔI RĂNG HỖN HỢP GIAI ĐOẠN SỚM KHI ĐIỀU TRỊ BẰNG HÀM THÁO LẮP CHỨC NĂNG
Authors: Phạm Thu Trang 
Published: February 2023

Mục tiêu: Đánh giá sự thay đổi trước sau điều trị trên lâm sàng sau khi điều trị cắn ngược vùng cửa trên hàm răng hỗn hợp giai đoạn sớm bằng hàm tháo lắp chức năng. Đối tượng và phương pháp nghiên cứu: Nghiên cứu được thực hiện trên 30 bệnh nhân có cắn ngược vùng cửa trong độ tuổi răng hỗn hợp đến khám và điều trị bằng hàm chức năng Myobrace i3 tại bệnh viện răng hàm mặt trung ương Hà Nội, sử dụng kết quả thăm khám lâm sàng. Kết quả: Chiều cao tầng mặt dưới tăng 0,37 ± 0,37 mm, độ cắn chìa tăng -3,73 ± 1,50 mm; Thói quen xấu đẩy lưỡi đã được loại bỏ 85,7% , Phanh lưỡi bám thấp được loại bỏ hoàn toàn 100%, vị trí lưỡi đặt thấp loại bỏ 80%. Thời gian điều trị trung bình đến khi hết ngược là 14,47 ± 1,31 tháng. Bệnh nhân tuân thủ tốt các bước điều trị. Kết luận: Các bệnh nhân có khớp cắn ngược vùng cửa trên hàm răng hỗn hợp giai đoạn sớm có vị trí lưỡi đặt thấp, hay kèm theo thói quen xấu đẩy lưỡi, chiều cao tầng mặt dưới thấp và tương quan răng 6 theo Angle chủ yếu loại III sau đó đến loại I và không có tương quan loại II
Nabilone for the Treatment of Posttraumatic Stress Disorder: A 2023 Update
Authors: Young Calvin , MacDougall Danielle , Hamson Angie 
Published: February 2023

One relevant systematic review of high methodological quality did not include any randomized controlled trials (RCTs) on the effectiveness of nabilone for the treatment of posttraumatic stress disorder (PTSD).
We did not find any evidence-based guidelines on the use of nabilone for adults with PTSD.
CERTAIN ASPECTS OF THE DEPRIVATION AND RESTRICTION OF PARENTAL RIGHTS AS A MEASURE OF LEGAL INFLUENCE
Authors:   Higher School of Judges under the Supreme  Judicial Council of the Republic of Uzbekistan, Khayitov Muzaffar 
Published: February 2023

Maintaining a reasonable ratio of parental and child relationships in the family environment is one of the important tasks of each society. The development of a child as a perfect person is inextricably linked with a healthy atmosphere in the family, as well as the correct relationship between parents and children. In this regard, the fulfilment of parental obligations in relation to the child, established by Family Law, plays an important role. Nevertheless, in society, due to the unhealthy environment in some families, parental obligations are not fulfilled to the proper extent, and the norms of the law on the relationship between parent and child are not observed. This entails certain measures of responsibility in the field of family law. For this reason, this socially negative situation that exists in society is studied by scientists and specialists as an object of research. The article considers the deprivation of parental rights, its restriction and its grounds as a measure of family legal influence. The grounds for deprivation of parental rights are based on the fact that the parent or one of them has committed an unlawful act or inaction. At the same time, it was emphasized that the deprivation of parental rights, and its restriction is at the same time a measure to defend and protect the child from the negative impact of the parent, and the family environment, to ensure the rights and legitimate interests of the child.
Concentrations of dissolved dimethyl sulfide (DMS), methanethiol and other trace gases in context of microbial communities from the temperate Atlantic to the Arctic Ocean
Authors: Gros Valérie , Bonsang Bernard , Sarda-Estève Roland , Nikolopoulos Anna , Metfies Katja , Wietz Matthias , Peeken Ilka 
Published: February 2023

Abstract. Dimethyl sulfide (DMS) plays an important role in the atmosphere by influencing the formation of aerosols and cloud condensation nuclei. In
contrast, the role of methanethiol (MeSH) for the budget and flux of reduced sulfur remains poorly understood. In the present study, we
quantified DMS and MeSH together with the trace gases carbon monoxide (CO), isoprene, acetone, acetaldehyde and acetonitrile in
North Atlantic and Arctic Ocean surface waters, covering a transect from 57.2 to 80.9∘ N in high spatial resolution in May–June
2015. Whereas isoprene, acetone, acetaldehyde and acetonitrile concentrations decreased northwards, CO, DMS and MeSH retained
substantial concentrations at high latitudes, indicating specific sources in polar waters. DMS was the only compound with a higher average concentration in
polar (31.2 ± 9.3 nM) than in Atlantic waters (13.5 ± 2 nM), presumably due to DMS originating from sea ice. At
eight sea-ice stations north of 80∘ N, in the diatom-dominated marginal ice zone, DMS and chlorophyll a markedly correlated
(R2 = 0.93) between 0–50 m depth. In contrast to previous studies, MeSH and DMS did not co-vary, indicating decoupled
processes of production and conversion. The contribution of MeSH to the sulfur budget (represented by DMS + MeSH) was on
average 20 % (and up to 50 %) higher than previously observed in the Atlantic and Pacific oceans, suggesting MeSH as an important
source of sulfur possibly emitted to the atmosphere. The potential importance of MeSH was underlined by several correlations with bacterial
taxa, including typical phytoplankton associates from the Rhodobacteraceae and Flavobacteriaceae families. Furthermore, the
correlation of isoprene and chlorophyll a with Alcanivorax indicated a specific relationship with isoprene-producing
phytoplankton. Overall, the demonstrated latitudinal and vertical patterns contribute to understanding how concentrations of central marine trace
gases are linked with chemical and biological dynamics across oceanic waters.
STUDY ON PERCEPTION OF CITY GOVERNMENTS REGARDING INNOVATION IN FINANCING OF URBAN INFRASTRUCTURE
Authors: Tamara Dewi , Djonoputro Bernardus , Wibawa Arie 
Published: February 2023

This paper aims to study the perception from city government regarding the financing innovation of city’s infrastructure. Cities need to provide basic infrastructure services—clean water, power and electricity, roads, public transit, sewage systems, telecommunications, schools, hospitals, to name a few — to support growth. Infrastructure is capital-intensive and expensive to build and, once built, lasts a long time. Apart from the fiscal aspect, the readiness of Indonesian cities to expedite urban infrastructure developments varies from one city to another. In this regard, city administrations need to increase the human resource capacity to support infrastructure development. With the high-demand of infrastructure provisions, high numbers of employees are needed to meet the demand as the current government priority sets ambitious targets in developing the infrastructure.
There are dominant factors that hinder infrastructure development in Indonesian cities:
Lack of financial capacity, matching private sector with financially viable projects, lack of capacity in human resources, regulatory and political risks, and land dispute and land acquisition. To overcome this, city governments need to innovate around financing methods in a highly regulated finance regime. Moreover, this study seek to understand the challenges faced by five Indonesian city governments in finding innovative ideas in financing the needed infrastructure.