bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perbedaan Tingkat Kepatuhan Penggunaan APD (Alat Pelindung Diri ) Dan Tingkat Higiene Tenaga Di Instalasi Gizi (Studi di dua Rumah Sakit Swasta di Kota Banjarmasin Tahun 2018)
Authors: Sari Yulianti Nur Wulan , Abdurrachim Rijanti 
Published: March 2023

Latar Belakang : Penjamah makanan sebagai salah satu kontributor terjadinya kontaminasi makanan. Higiene tenaga perlu diperhatikan dalam pengolahan makanan. Dalam pencapaian dan terlaksananya higiene tenaga penyelenggaraan makanan, perlunya penggunaan alat pelindung diri (APD) yang berguna agar keamanan makanan pasien terjamin serta menghindari kecelakaan kerja saat bekerja. Tujuan dari penelitian ini untuk mengetahui perbedaan tingkat kepatuhan penggunaan APD dan tingkat higiene tenaga di Instalasi Gizi Rumah Sakit A dan Rumah Sakit B Banjarmasin. Metode : Jenis penelitian adalah observasional analitik menggunakan penelitian komparatif. Populasi dalam penelitian ini adalah petugas di Ruang Instalasi Gizi Rumah Sakit Bdan Rumah Sakit Islam Banjarmasin. Sampelnya yaitu 42 orang yang terdiri dari kriteria inklusi yang diambil dengan menggunakan teknik total sampling. Analisis data menggunakan uji Mann-Whitney. Hasil : tingkat kepatuhan penggunaan APD di Instalasi Gizi Rumah SakitAjumlah terbanyak dikategori cukup patuh yaitu 39% dan di Rumah Sakit B Banjarmasin dikategori tidak patuh yaitu 54%. Pada tingkat higiene tenaga di Instalasi Gizi Rumah SakitAkategori baik sebesar 78% dan kategori sedang sebesar 22% dan di Rumah Sakit B Banjarmasin kategori baik sebesar 63% dan kategori sedang sebesar 38%. Kesimpulan : Tidak ada perbedaan pada tingkat kepatuhan penggunaan APD dan higiene tenaga di Instalasi Gizi Rumah SakitAdan Rumah Sakit BBanjarmasin. Saran : Bagi kedua Rumah Sakit disarankan untuk lebih tegas dalam hal pengawasan dan sanksi agar tenaga penyelenggaraan makanannya lebih mematuhi dalam peraturan atau SOP yang telah ditetapkan.

Kata Kunci : Kepatuhan Penggunaan APD, Higiene Tenaga, Instalasi Gizi,Tenaga Penyelengaraan
Makanan
RELATIONSHIP OF FOOD CONSUMPTION PATTERNS AND INSTANT BEVERAGES, VEGETABLE CONSUMPTION AND FRUIT, PHYSICAL ACTIVITIES, STRESS LEVELS WITH NUTRITIONAL STATUS OF HYPERTENSION PATIENTS (Study in Banjarbaru Sungai Besar Health Center Work Area)
Authors: Yanti Helda , Dewi Zulfiana 
Published: March 2023

Hipertensi merupakan PTM atau salah satu penyakit sistem kardiovaskuler yang paling banyak ditemui dibandingkan dengan penyakit sistem kardiovaskuler lain. Tujuan untuk mengetahui hubungan pola konsumsi makanan dan minuman instan, sayur buah, aktivitas fisik, tingkat stres dengan status gizi pada penderita hipertensi di wilayah kerja Puskesmas Sungai Besar Banjarbaru Tahun 2019.
Metode ini bersifat observasional analitik dengan rancangan cross sectional. Populasi penelitian adalah semua pasien hipertensi yang ada di wilayah kerja Puskesmas Sungai Besar Banjarbaru sebanyak 160 dan sampel sebanyak 62 orang diambil dengan teknik purposive sampling. Data primer dikumpulkan dengan cara wawancara dan pengukuran sedangkan data sekunder dengan cara pencatatan langsung arsip Puskesmas. Analisis data dengan uji Korelasi Rank Sperman dengan tingkat kepercayaan 95% (Î±=0,05)
Hasil penelitian menjukkan 50% pada usia â‰¥ 36 tahun, 69,4% lebih banyak pada perempuan, 61,3% sering mengkonsumsi makanan dan minuman instan, 56,5% jarang mengkonsumsi sayur dan buah, 51,6% aktivitas ringan, 43,5% tingkat stres sedang, 38,7% status gizi gemuk. Ada hubungan yang bermakna antara pola konsumsi makanan dan minuman instan dengan status gizi, ada hubungan antara pola konsumsi sayur dan buah dengan status gizi, ada hubungan aktivitas fisik dengan staus gizi, dan tidak ada hubungan antara tingkat stres dengan status gizi.
Saran kepada responden agar mengurangi konsumsi makanan dan minuman instan diganti dengan makanan yang bergizi seimbang dan perbanyak buah dan sayur serta berolahraga secara rutin. Bagi Puskesmas diharapkan agar meningkatkan pelayanan kesehatan khususnya bagi penderita hipertensi
Ervandashat : résumé d’une étude archéologique de 2005-2014
Authors: Parsamyan Arevik , Gabrielyan Armine 
Published: March 2023

Le site d’Ervandashat se situe entre les villages d’Ervandashat et de Bagaran, près du confluent de l’Araxe et de l’Akhurian, dans la région d’Armavir (carte n° 1). Le territoire entre ces deux villages est non seulement riche en monuments historiques, mais fait aussi partie de ces territoires uniques où il est possible de trouver des matériaux ethnographiques remarquables. Ici, les monuments historiques, les sites archéologiques, les khatchkars et les stèles cultuelles, auxquels il faut ajouter le paysage magnifique, créent un remarquable ensemble culturel.
Substitusi Tepung Sagu dan Modified Cassava Flour (Mocaf) pada Produk Makanan Tradisional Ilepa’o
Authors: Zainuddin Asniwati , Xyzquolyna Deyvie , Laboko Asriani I , Anto Anto , Mokoginta Sri Yuniati 
Published: March 2023

Tujuan penelitian ini untuk menganalisis kadar air, kadar abu, kadar protein dan tingkat penerimaan panelis terhadap produk tradisional Ilepa’o yang diolah dengan mensubstitusi tepung mocaf pada tepung sagu. Penelitian ini menggunakan rancangan acak lengkap atau (RAL) dengan 4 perlakuan dan 3 ulangan. Perlakuan penelitian diperoleh yaitu P1 = 50g tepung sagu, P2 = 50g tepung mocaf, P3= 10g tepung sagu+40g tepung mocaf, dan P4=25g tepung sagu+25g tepung mocaf. Hasil analisa yang di peroleh adalah kadar air P1= 50,41%, P2= 58,90%, P3= 57,86%, dan P4= 55,02%. Kadarabu P1= 1,16%, P2= 2,15%, P3=2,38%, dan P4=2,33%. Kadar protein P1= 11,84%, P2= 11,87%, P3= 9,16%, dan P4= 9,56%. Hasil uji organoleptikpada makanan tradisional ilepao yang paling di sukai oleh panelis (dari segi rasa, aroma, dan tekstur) adalah perlakuan P4 yaitu dengan formulasi 25gtepung sagu+25g tepung mocaf. Penambahan tepung mocaf memberikan pengaruh yang tidak nyata terhadap kadar air dan kadar protein, sedangkan pada kadar abu memberikan pengaruh yang nyata pada produk ilepa’o.
El estado emocional y el rendimiento académico una aproximación a la realidad actual
Authors: Moreano Núñez Emily Estefania , Saltos Salazar Lenin Fabián , Gavilanes López Wilma Lorena , Andrade Alban Jorge Rodrigo 
Published: March 2023

Introducción. Los estados emocionales están relacionados fundamentalmente con procesos cognitivos como la atención, la percepción, la memoria y el aprendizaje, la importancia de su inserción en el contexto educativo es esencial, con el fin de proponer a los estudiantes, alternativas y estrategias para que la modulación de las emociones no afecte el rendimiento académico. Objetivo. Esta investigación tiene como objetivo analizar la relación entre el estado emocional y el rendimiento académico y proponer una alternativa para contribuir al desarrollo de los procesos de reconocimiento y regulación de los estados emocionales, reduciendo el fracaso académico y el bajo rendimiento. La investigación se llevó a cabo en el Colegio Belisario Quevedo de Pujilí. Metodología. Se realizó una investigación de campo, descriptiva, experimental y cuantitativa. El universo total es de 278 alumnos, de los cuales mediante la fórmula de muestreo y el muestreo aleatorio simple dieron como resultado una muestra de 161 alumnos que fueron evaluados mediante el Cuestionario del Test de Eysenck y la Escala de Autoconcepto Académico (EAA). Resultados. Los resultados mostraron un nivel significativo de Inestabilidad Emocional y dificultades en Autoestima, Felicidad, Autonomía, tendencias hacia la Depresión, Ansiedad, Obsesividad, Dependencia, Hipocondría y Sentimiento de Culpa; En el caso del Rendimiento Académico: el Rendimiento Académico está presente, así como el Autoconcepto Académico, la Autoeficacia es considerada como baja. Conclusión. Existe una relación directa con tendencia fuerte - moderada entre la autoestima, la ansiedad y el rendimiento académico; la ansiedad y la autoeficacia y la culpa y el autoconcepto académico. Esto demuestra que el estado emocional afecta significativamente al rendimiento académico.
INHERITANCE DISTRIBUTION FOR "KHUNTHA MUSHKIL" (SISSY) IN ISLAM:
Authors: Abizar Mukhammad Hafidz 
Published: March 2023

This article is result of library research with a normative legal approach. Legal materials and data were obtained from Islamic legal norms regarding inheritance and khuntsa obtained from the texts of the Qur'an and Hadith, as well as the opinions of the jurists. This thesis discusses the distribution of khuntsa inheritance based on the opinion of Imam Ali As-Shobuni and Imam Abu Hanifah. People who do not have a clear gender status, not male and not female, are called khuntsa in Islamic law. One of the problems of khuntsa is in determining the right of inheritance. The Qur'an does not clearly state the portion of khuntha inheritance. This study concludes that in the unclear gender of khuntsa, it can be determined by two things, namely first, signs of maturity and second, where does urine come from. This argument is put forward using the istidlal theory used by Imam Ali As-Shobuni and Imam Abu Hanifah. If a khuntsa has a clear gender status, then this status follows the law of inheritance
Keyword : Khuntha mushkil, sissy, inheritance.

Abstrak
Artikel ini adalah hasil dari penelitian kepustakaan dengan pendekatan hukum normatif. Bahan hukum dan data diperoleh dari norma- norma hukum Islam tentang kewarisan dan khuntsa yang diperoleh dari nash al-Qur‟an dan Hadits, serta pendapat para fuqaha‟. Tesis ini mendiskusikan pembagian warisan khuntsa berdasarkan pendapat Imam Ali As-Shobuni dan Imam Abu Hanifah. orang yang tidak mempunyai status jenis kelamin yang jelas, bukan laki-laki dan bukan perempuan disebut dengan istilah khuntsa dalam hukum islam. Salah satu dari permasalahan khuntsa adalah dalam hal menentukan hak kewarisannya. Al-Qur‟an tidak menyebutkan secara jelas bagian waris khuntha. Penelitian ini menyimpulkan bahwa dalam ketidak jelasan jenis kelamin khuntsa, dapat ditentukan dengan dua hal, yaitu pertama, tanda-tanda kedewasaannya dan kedua, darimana ia mengeluarkan air kencing. Argumen ini diajukan dengan menggunakan teori istidlal yang digunakan oleh Imam Ali As-Shobuni dan Imam Abu Hanifah. Bila seorang khuntsa telah jelas status jenis kelaminnya, maka status ini mengikuti pada hukum kewarisannya.
Kata Kunci : Khuntha mushkil, banci, pembagian waris
Strength of a cement-based dental material: Early age testing and first micromechanical modeling at mature age
Authors: Dohnalík Petr , Hellmich Christian , Richard Gilles , Pichler Bernhard L. A. 
Published: March 2023

The compressive strength evolution of 37 centigrade-cured Biodentine, a cement-based dental material, is quantified experimentally by crushing cylindrical specimens with length-to-diameter ratios amounting to 1.84 and 1.34, respectively, at nine different material ages ranging from 1 h to 28 days. After excluding strength values significantly affected by imperfections, formulae developed for concrete are i) adapted for inter- and extrapolation of measured strength values, and ii) used for quantification of the influence of the slenderness of the specimens on the compressive strength. The microscopic origin of the macroscopic uniaxial compressive strength of mature Biodentine is investigated by means of a micromechanics model accounting for lognormal stiffness and strength distributions of two types of calcite-reinforced hydrates. The following results are obtained: The material behavior of Biodentine is non-linear in the first few hours after production. After that, Biodentine behaves virtually linear elastic all the way up to sudden brittle failure. The strength evolution of Biodentine can be well described as the exponential of a function involving the square root of the inverse of the material age. The genuine uniaxial compressive strength evolution can be quantified using a correction formula taken from a standard for testing of concrete, which accounts for length-to-diameter ratios of cylindrical samples deviating from 2. Multiscale modeling suggests that 63% of the overall material volume, occupied by dense calcite-reinforced hydration products, fail virtually simultaneously. This underlines the highly optimized nature of the studied material.
Investigating the induction of polyphenol biosynthesis in the cultured Cycolocarya paliurus cells and the stimulatory mechanism of co-induction with 5-aminolevulinic acid and salicylic acid
Authors: Ling Li-Juan , Wang Meng , Pan Chuan-Qing , Tang Dao-Bang , Yuan En , Zhang Yuan-Yuan , Chen Ji-Guang , Peng Da-Yong , Yin Zhong-Ping 
Published: March 2023

Background: Plant cell culture technology is a potential way to produce polyphenols, however, this way is still trapped in the dilemma of low content and yield. Elicitation is regarded as one of the most effective ways to improve the output of the secondary metabolites, and therefore has attracted extensive attention.Methods: Five elicitors including 5-aminolevulinic acid (5-ALA), salicylic acid (SA), methyl jasmonate (MeJA), sodium nitroprusside (SNP) and Rhizopus Oryzae Elicitor (ROE) were used to improve the content and yield of polyphenols in the cultured Cyclocarya paliurus (C. paliurus) cells, and a co-induction technology of 5-ALA and SA was developed as a result. Meanwhile, the integrated analysis of transcriptome and metabolome was adopted to interpret the stimulation mechanism of co-induction with 5-ALA and SA.Results: Under the co-induction of 50 μM 5-ALA and SA, the content and yield of total polyphenols of the cultured cells reached 8.0 mg/g and 147.12 mg/L, respectively. The yields of cyanidin-3-O-galactoside, procyanidin B1 and catechin reached 28.83, 4.33 and 2.88 times that of the control group, respectively. It was found that expressions of TFs such as CpERF105, CpMYB10 and CpWRKY28 increased significantly, while CpMYB44 and CpTGA2 decreased. These great changes might further make the expression of CpF3′H (flavonoid 3′-monooxygenase), CpFLS (flavonol synthase), CpLAR (leucoanthocyanidin reductase), CpANS (anthocyanidin synthase) and Cp4CL (4-coumarate coenzyme A ligase) increase while CpANR (anthocyanidin reductase) and CpF3′5′H (flavonoid 3′, 5′-hydroxylase) reduce, ultimately enhancing the polyphenols accumulationConclusion: The co-induction of 5-ALA and SA can significantly promote polyphenol biosynthesis in the cultured C. paliurus cells by regulating the expression of key transcription factors and structural genes associated with polyphenol synthesis, and thus has a promising application.
Geographically weighted linear combination test for gene-set analysis of a continuous spatial phenotype as applied to intratumor heterogeneity
Authors: Amini Payam , Hajihosseini Morteza , Pyne Saumyadipta , Dinu Irina 
Published: March 2023

Background: The impact of gene-sets on a spatial phenotype is not necessarily uniform across different locations of cancer tissue. This study introduces a computational platform, GWLCT, for combining gene set analysis with spatial data modeling to provide a new statistical test for location-specific association of phenotypes and molecular pathways in spatial single-cell RNA-seq data collected from an input tumor sample.Methods: The main advantage of GWLCT consists of an analysis beyond global significance, allowing the association between the gene-set and the phenotype to vary across the tumor space. At each location, the most significant linear combination is found using a geographically weighted shrunken covariance matrix and kernel function. Whether a fixed or adaptive bandwidth is determined based on a cross-validation cross procedure. Our proposed method is compared to the global version of linear combination test (LCT), bulk and random-forest based gene-set enrichment analyses using data created by the Visium Spatial Gene Expression technique on an invasive breast cancer tissue sample, as well as 144 different simulation scenarios.Results: In an illustrative example, the new geographically weighted linear combination test, GWLCT, identifies the cancer hallmark gene-sets that are significantly associated at each location with the five spatially continuous phenotypic contexts in the tumors defined by different well-known markers of cancer-associated fibroblasts. Scan statistics revealed clustering in the number of significant gene-sets. A spatial heatmap of combined significance over all selected gene-sets is also produced. Extensive simulation studies demonstrate that our proposed approach outperforms other methods in the considered scenarios, especially when the spatial association increases.Conclusion: Our proposed approach considers the spatial covariance of gene expression to detect the most significant gene-sets affecting a continuous phenotype. It reveals spatially detailed information in tissue space and can thus play a key role in understanding the contextual heterogeneity of cancer cells.
Peroxidase-like MoS2/Ag nanosheets with synergistically enhanced NIR-responsive antibacterial activities
Authors: Chen Huiying , Zhao Xinshuo , Cui Bingbing , Cui Haohao , Zhao Mengyang , Shi Jun , Li Jingguo , Zhou Zhan 
Published: March 2023

Pathogenic microbial infections have been threatening public health all over the world, which makes it highly desirable to develop an antibiotics-free material for bacterial infection. In this paper, molybdenum disulfide (MoS2) nanosheets loaded with silver nanoparticles (Ag NPs) were constructed to inactive bacteria rapidly and efficiently in a short period under a near infrared (NIR) laser (660 nm) in the presence of H2O2. The designed material presented favorable features of peroxidase-like ability and photodynamic property, which endowed it with fascinating antimicrobial capacity. Compared with free MoS2 nanosheets, the MoS2/Ag nanosheets (denoted as MoS2/Ag NSs) exhibited better antibacterial performance against Staphylococcus aureus by the generated reactive oxygen species (ROS) from both peroxidase-like catalysis and photodynamic, and the antibacterial efficiency of MoS2/Ag NSs could be further improved by increasing the amount of Ag. Results from cell culture tests proved that MoS2/Ag3 nanosheets had a negligible impact on cell growth. This work provided new insight into a promising method for eliminating bacteria without using antibiotics, and could serve as a candidate strategy for efficient disinfection to treat other bacterial infections.
Effects of emergency/nonemergency cervical cerclage on the vaginal microbiome of pregnant women with cervical incompetence
Authors: Xiao Yunshan , Huang Shiting , Yu Weiwei , Ni Yan , Lu Danni , Wu Quanfeng , Leng Qin , Yang Ting , Ni Meilan , Xie Jingxian , Zhang Xueqin 
Published: March 2023

BackgroundEvaluation of the therapeutic effects of cerclage on preterm birth (PTB) caused by cervical incompetence remains challenging. The vaginal microbiome is associated with preterm births. Thus, this study aimed to analyse the vaginal microbiota of patients with cervical incompetence, explore the relationship between the composition of the vaginal microbiota before cervical cerclage and at term delivery, and assess the effect of cervical cerclage on the vaginal microbiota.MethodsPatients (n = 30) underwent cerclage performed by the same surgical team. Vaginal swabs were obtained pre-surgery and seven days post-surgery. A gestational age-matched cohort of healthy pregnant women (n = 20) (no particular abnormality during pregnancy, delivery at term) was used as the control group and sampled during a comparable pregnancy. All collected vaginal swabs were analysed by 16S rRNA gene sequencing.ResultsWhen comparing the healthy control and cervical cerclage groups, the enriched microorganism in the healthy controls was G. Scardovia, and the enriched microorganism of the cerclage was G. Streptococcus. α diversity was significantly increased in patients who received cerclage with preterm delivery compared with those with full-term delivery, and the enriched microorganism was F. Enterococcus. A comparison before and after nonemergency cerclage suggested that the enriched microorganisms were G. Lactobacillus and F. Lactobacillaceae before surgery. After nonemergency cerclage, the enriched microorganisms were F. Enterobacteriaceae and C. Gammaproteobacteria. Vaginal microbiota diversity significantly increased, and the proportion of women with Lactobacillus spp.-depleted microbiomes increased after emergency cerclage. Significant differences in β diversity were found between the groups. Before the emergency cerclage, the enriched microorganisms were G. Lactobacillus, O. Alteromonadales, and P. Firmicutes. After emergency cerclage, the enriched microorganisms were P. Actinobacteria, C. Actinobacteria, P. Proteobacteria, F. Bifidobacteriaceae, O. Bifidobacteriales, G. Gardnerella, and G. Veillonella.ConclusionCerclage (particularly emergency cerclage) may alter the vaginal microbiota by increasing microbiota diversity, decreasing vaginal Lactobacillus abundance, and increasing the abundance of pathogenic bacteria that are not conducive to pregnancy maintenance, thereby affecting surgical efficacy. Therefore, the role of the vaginal microbiome should be considered when developing treatment strategies for pregnant women with cervical incompetence.Clinical trial registrationhttps://www.chictr.org.cn, identifier ChiCTR2100046305.
The effect of argon cold atmospheric plasma on the metabolism and demineralization of oral plaque biofilms
Authors: Zhao Haowei , Wang Xu , Liu Zhuo , Wang Ye , Zou Ling , Chen Yu , Han Qi 
Published: March 2023

ObjectiveThe aim of this study was to design and optimize a cold atmospheric plasma (CAP) device that could be applied in an oral environment and to study its effects on plaque biofilm metabolism and regrowth, as well as microbial flora composition and enamel demineralization.MethodCAP was obtained through a dielectric barrier discharge device; the optical properties were analyzed using emission spectroscopy. The electrochemical analysis of plasma devices includes voltametric characteristic curves and Lissajous. The Streptococcus mutans (UA159) and saliva biofilms were treated in vitro, and the effects of CAP on biofilm metabolism were investigated using MTT and lactate dehydrogenase assays. The duration of antibacterial activity on biofilms was examined, scanning electron microscopy was used to observe the morphology of biofilms, and 16S rRNA sequencing was used to explore the influence of CAP on the microbial flora composition of saliva biofilms. An in vitro model of biofilm-enamel demineralization was designed, and the effect of CAP on enamel demineralization was evaluated by micro surface hardness and micro-CT analysis.ResultsCAP had antibacterial proliferative ability toward Streptococcus mutans biofilms and saliva biofilms and was stronger than ultraviolet under the same tested conditions. After 24 h, the antibacterial effect disappeared, which proved the short-term timeliness of its bactericidal ability. CAP can inhibit the acid production of biofilms, and its inhibitory effect on saliva biofilms can be extended to 24 h. CAP had a strong ability to regulate the composition of plaque biofilms, especially for Lactococcus proliferation, a major acid-producing bacterium in microcosm biofilms. The CAP-treated enamels were more acid-tolerant than non-treated controls.ConclusionCAP had an explicit bactericidal effect on caries-related biofilms, which is a short-term antibacterial effect. It can inhibit the acid production of biofilms and has a downregulation effect on Lactococcus in saliva biofilms. CAP can help reduce demineralization of enamel.