bluuebunny/crossref_metadata_2025_split huggingface dataset:
The fuzzy Kullback–Leibler divergence for estimating parameters of the probability distribution in fuzzy data: an application to classifying Vietnamese Herb Leaves
Authors: Le Hoa , Sang Vu Ngoc Thanh , Lam Thuy Le Nhi , Bao Pham The 
Published: September 2023

AbstractIn this paper, we address the challenge of estimating probability distributions which are typically represented by parameter-based values. However, this estimation is prone to errors and does not comprehensively capture the nature of real-world data. Additionally, real-world data often follows a mixed form of probability distributions, where sub-datasets may contain incomplete information. To enhance flexibility, especially in classification problems, we propose a new method for describing parameters estimated through Bayesian statistics. Our method introduces fuzzy parameters and assesses the similarity between probability distributions using the fuzzy extended Kullback–Leibler divergence. We demonstrate the practical application of our approach in Vietnamese Herb Leaves classification. By incorporating fuzzy parameters and leveraging Bayesian statistics, our method provides more robust estimations of probability distributions and enables improved flexibility in classification tasks.
Ecology and resistance to UV light and antibiotics of microbial communities on UV cabins in the dermatology service of a Spanish hospital
Authors: Molina-Menor Esther , Carlotto Nicolás , Vidal-Verdú Àngela , Pérez-Ferriols Amparo , Pérez-Pastor Gemma , Porcar Manuel 
Published: September 2023

AbstractMicroorganisms colonize all possible ecological habitats, including those subjected to harsh stressors such as UV radiation. Hospitals, in particular the UV cabins used in phototherapy units, constitute an environment in which microbes are intermittently subjected to UV irradiation. This selective pressure, in addition to the frequent use of antibiotics by patients, may represent a threat in the context of the increasing problem of antimicrobial resistance. In this work, a collection of microorganisms has been established in order to study the microbiota associated to the inner and outer surfaces of UV cabins and to assess their resistance to UV light and the antibiotics frequently used in the Dermatology Service of a Spanish hospital. Our results show that UV cabins harbor a relatively diverse biocenosis dominated by typically UV-resistant microorganisms commonly found in sun-irradiated environments, such as Kocuria, Micrococcus or Deinococcus spp., but also clinically relevant taxa, such as Staphylococcus or Pseudomonas spp. The UV-radiation assays revealed that, although some isolates displayed some resistance, UV is not a major factor shaping the biocenosis living on the cabins, since a similar pool of resistant microorganisms was identified on the external surface of the cabins. Interestingly, some Staphylococcus spp. displayed resistance to one or more antibiotics, although the hospital reported no cases of antibiotic-resistance infections of the patients using the cabins. Finally, no association between UV and antibiotic resistances was found.
Thermal tolerance and vulnerability to warming differ between populations of wild Oncorhynchus mykiss near the species’ southern range limit
Authors: Dressler T. L. , Han Lee V. , Klose K. , Eliason E. J. 
Published: September 2023

AbstractFish habitat temperatures are increasing due to human impacts including climate change. For broadly distributed species, thermal tolerance can vary at the population level, making it challenging to predict which populations are most vulnerable to warming. Populations inhabiting warm range boundaries may be more resilient to these changes due to adaptation or acclimatization to warmer temperatures, or they may be more vulnerable as temperatures may already approach their physiological limits. We tested functional and critical thermal tolerance of two populations of wild Oncorhynchus mykiss near the species’ southern range limit and, as predicted, found population-specific responses to temperature. Specifically, the population inhabiting the warmer stream, Piru Creek, had higher critical thermal maxima and higher functional thermal tolerance compared to the population from the cooler stream, Arroyo Seco. Arroyo Seco O. mykiss are more likely to experience a limitation of aerobic scope with warming. Piru Creek O. mykiss, however, had higher resting metabolic rates and prolonged exercise recovery, meaning that they could be more vulnerable to warming if prey or dissolved oxygen become limited. Temperature varies widely between streams near the O. mykiss southern range limit and populations will likely have unique responses to warming based on their thermal tolerances and metabolic requirements.
Pedogenesis of typical zonal soil drives belowground bacterial communities of arable land in the Northeast China Plain
Authors: Hou Meng , Zhao Xiaorui , Wang Yao , Lv Xuemei , Chen Yimin , Jiao Xiaoguang , Sui Yueyu 
Published: September 2023

AbstractBelowground bacterial communities play essential roles in maintaining ecosystem multifunction, while our understanding of how and why their distribution patterns and community compositions may change with the distinct pedogenetic conditions of different soil types is still limited. Here, we evaluated the roles of soil physiochemical properties and biotic interactions in driving belowground bacterial community composition across three typical zonal soil types, including black calcium soil (QS), typical black soil (HL) and dark brown soil (BQL), with distinct pedogenesis on the Northeast China Plain. Changes in soil bacterial diversity and community composition in these three zonal soil types were strongly correlated with soil pedogenetic features. SOC concentrations in HL were higher than in QS and BQL, but bacterial diversity was low, and the network structure revealed greater stability and connectivity. The composition of the bacterial community correlated significantly with soil pH in QS but with soil texture in BQL. The bacterial co-occurrence network of HL had higher density and clustering coefficients but lower edges, and different keystone species of networks were also detected. This work provides a basic understanding of the driving mechanisms responsible for belowground bacterial biodiversity and distribution patterns over different pedogenetic conditions in agroecosystems.
Boosting the adsorptive and photocatalytic performance of MIL-101(Fe) against methylene blue dye through a thermal post-synthesis modification
Authors: Fattahi Mehdi , Niazi Zohreh , Esmaeili Fatemeh , Mohammadi Ali Akbar , Shams Mahmoud , Nguyen Le Binh 
Published: September 2023

AbstractPhotocatalytic degradation under ultra-low powered light is a viable advanced oxidation process technique against extensive emerging contaminants. As a new and remarkable class of nanoporous materials, metal-organic frameworks (MOFs), attract interest for the supreme adsorptive and photocatalytic functionalities. An outstanding MOF, MIL-101(Fe) chosen as a photocatalyst template for the synthesis of α-Fe2O3 by a simple thermal modification to improve the structural properties toward methylene blue (MB) eradication. Octahedron-like α-Fe2O3 photocatalyst (Modified MIL-101(Fe), M-MIL-101(Fe)) was superior in dispersion and separation properties in aqueous medium. Moreover, the adsorptive and catalytic performance was increased for modified form by ~ 7.3% and ~ 17.1% compared to pristine MIL-101(Fe), respectively. Synergistic improvement of MB removal achieved by simultaneous adsorption/degradation under 5-W LED irradiation. Parametric study indicated an 18.1% and 44.5% improvement in MB removal was observed by increasing pH from 4 to 10, and M-MIL-101(Fe) dose from 0.2 to 1 g L−1, respectively. MB removal followed the pseudo-second-order kinetics model and the process efficiency dropped by 38% as MB concentration increased from 5 to 20 mg L−1. Radical trapping tests revealed the significant role of $${\mathrm{OH}}^{.}$$

OH

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and electron radicals as the major participants in dye degradation. A significant loss in the efficiency of M-MIL-101(Fe) was observed in the reusability tests that is good to study further. In conclusion, a simple thermal post-synthesis modification on MIL-101(Fe) improved its structural, catalytic, and adsorptive properties against MB.
Script-driven imagery of socially salient autobiographical memories in major depressive disorder
Authors: Gillard Julia , Werner-Seidler Aliza , Dalgleish Tim , Stretton Jason 
Published: September 2023

AbstractCues of social rejection and affiliation represent proximal risk and protective factors in the onset and maintenance of depression. Such cues are thought to activate an evolutionarily primed neuro-cognitive alarm system, alerting the agent to the benefits of inclusion or the risk of social exclusion within social hierarchies focused on ensuring continued access to resources. In tandem, autobiographical memory is thought to be over-general and negatively biased in Major Depressive Disorder (MDD) which can contribute to maintenance and relapse. How memories of social rejection and affiliation are experienced and processed in MDD remains unexplored. Eighteen participants with recurrent and chronic MDD and 18 never-depressed controls listened to and vividly revisited autobiographical social experiences in an ecologically valid script-driven imagery paradigm using naturalistic memory narratives in an fMRI paradigm. Memories of Social Inclusion and Social Rejection broadly activated a common network of regions including the bilateral insula, thalamus and pre/postcentral gyrus across both groups. However, having a diagnosis of MDD was associated with an increased activation of the right middle frontal gyrus irrespective of memory type. Changes in positive affect were associated with activity in the dorsal ACC in the MDD group and in the insular cortex of the Control group. Our findings add to the evidence for complex representations for both positive and negative social signals in MDD and suggest neural sensitivity in MDD towards any socially salient information as opposed to selective sensitivity towards negative social experiences.
A leader supply-demand-based optimization for large scale optimal power flow problem considering renewable energy generations
Authors: Daqaq Fatima , Hassan Mohamed H. , Kamel Salah , Hussien Abdelazim G. 
Published: September 2023

AbstractThe supply-demand-based optimization (SDO) is among the recent stochastic approaches that have proven its capability in solving challenging engineering tasks. Owing to the non-linearity and complexity of the real-world IEEE optimal power flow (OPF) in modern power system issues and like the existing algorithms, the SDO optimizer necessitates some enhancement to satisfy the required OPF characteristics integrating hybrid wind and solar powers. Thus, a SDO variant namely leader supply-demand-based optimization (LSDO) is proposed in this research. The LSDO is suggested to improve the exploration based on the simultaneous crossover and mutation mechanisms and thereby reduce the probability of trapping in local optima. The LSDO effectiveness has been first tested on 23 benchmark functions and has been assessed through a comparison with well-regarded state-of-the-art competitors. Afterward, Three well-known constrained IEEE 30, 57, and 118-bus test systems incorporating both wind and solar power sources were investigated in order to authenticate the performance of the LSDO considering a constraint handling technique called superiority of feasible solutions (SF). The statistical outcomes reveal that the LSDO offers promising competitive results not only for its first version but also for the other competitors.
The transition from field emission to collisional space-charge limited current with nonzero initial velocity
Authors: Breen Lorin I. , Loveless Amanda M. , Darr Adam M. , Cartwright Keith L. , Garner Allen L. 
Published: September 2023

AbstractMultiple electron emission mechanisms often contribute in electron devices, motivating theoretical studies characterizing the transitions between them. Previous studies unified thermionic and field emission, defined by the Richardson-Laue-Dushman (RLD) and Fowler–Nordheim (FN) equations, respectively, with the Child-Langmuir (CL) law for vacuum space-charge limited current (SCLC); another study unified FN and CL with the Mott-Gurney (MG) law for collisional SCLC. However, thermionic emission, which introduces a nonzero injection velocity, may also occur in gas, motivating this analysis to unify RLD, FN, CL, and MG. We exactly calculate the current density as a function of applied voltage over a range of injection velocity (i.e., temperature), mobility, and gap distance. This exact solution approaches RLD, FN, and generalized CL (GCL) and MG (GMG) for nonzero injection velocity under appropriate limits. For nonzero initial velocity, GMG approaches zero for sufficiently small applied voltage and mobility, making these gaps always space-charge limited by either GMG at low voltage or GCL at high voltage. The third-order nexus between FN, GMG, and GCL changes negligibly from the zero initial velocity calculation over ten orders of magnitude of applied voltage. These results provide a closed form solution for GMG and guidance on thermionic emission in a collisional gap.
Autonomic function and motor subtypes in Parkinson’s disease: a multicentre cross-sectional study
Authors: Gu Si-Chun , Shi Rong , Gao Chen , Yuan Xiao-Lei , Wu You , Liu Zhen-Guo , Wang Chang-De , Zhao Shao-Rong , Chen Xiqun , Yuan Can-Xing , Ye Qing 
Published: September 2023

AbstractAutonomic symptoms (AS) are critical in Parkinson’s disease (PD). We aimed to determine the relative significance of clinical factors allowing predictions about incidence of AS, and examine AS profiles among PD patients by motor subtype and its relation to AS. The cross-sectional data of a multicentre sample, including 714 PD patients and 194 healthy controls from Parkinson’s Progression Marker Initiative study and Pingchan granule study were analyzed, stratified by PD subtypes [postural instability and gait disturbances (PIGD), tremor dominant (TD), and indeterminate] and domain autonomic dysfunction. Compared with healthy controls, PD patients scored higher in the total Scales for Outcomes in Parkinson's Disease-Autonomic dysfunction score and in several domain scores in particular, and there was a significant overlap in domain AS. Risk factors of individual domain autonomic dysfunction were heterogeneous. PIGD and indeterminate were the predominant subtypes in pupillomotor and thermoregulatory symptoms. TD and indeterminate were more likely to suffer from cardiovascular problem. The odd in sexual dysfunction was significant for PIGD. Gastrointestinal and urinary symptoms seemed not to be associated with a specific subtype. Our study demonstrated that AS were highly heterogeneous and 3 subtypes differed in autonomic performance, providing clues to understand mechanisms underlying AS in PD.
Robust analysis of a novel PANoptosis-related prognostic gene signature model for hepatocellular carcinoma immune infiltration and therapeutic response
Authors: Wei Yongguang , Lan Chenlu , Yang Chengkun , Liao Xiwen , Zhou Xin , Huang Xinlei , Xie Haixiang , Zhu Guangzhi , Peng Tao 
Published: September 2023

AbstractPANoptosis, an interplay between pyroptosis, apoptosis, and necroptosis, is deeply involved in cancer development and immunity. However, the influence of PANoptosis in hepatocellular carcinoma (HCC) remains to be further investigated. The differentially expressed PANoptosis-related genes (PANRGs) was screened in The Cancer Genome Atlas (TCGA) database. Accordingly, mutation, bioinformatics, and consensus clustering analyses were performed. Then, a prognostic risk model was developed by least absolute shrinkage and selection operator (LASSO) Cox regression. Furthermore, the prognostic value, immunity correlation and therapeutic response prediction ability of risk model were explored. A total of 18 PANRGs were differently expressed in the TCGA-HCC cohort and were mainly involved in cancer- and cell death-related signal pathways. Using unsupervised clustering method, we identified two PANRGs-mediated clustering patterns. The remarkable differences between the two clusters on overall survival (OS) and clinical features were demonstrated respectively. Based on the five-gene prognostic risk model, the calculated PANRG-scores were used to categorize the subgroups as high- and low-risk. Notably, the high-risk subgroup had a dismal prognosis and exhibited much lower immune infiltration levels of mast cells, nature killer cells and pDCs, but higher levels of aDCs, iDCs and Treg cells than those in the low-risk subgroup. Furthermore, we constructed a reliable nomogram combining clinical traits and PANRG-score to predict the OS of HCC patients. The significantly negative correlation between PANoptosis and tumor mutation burden (TMB), ferroptosis were revealed. In drug sensitivity analysis, the high-risk subgroup had a considerably lower TIDE score, suggesting a preferable response to immunotherapy, and may be more sensitive to Tipifarnib, Imatinib, Doxorubicin, and Gemcitabine. The upregulated mRNA expressions of FADD were validated in 16 paired HCC tissues of Guangxi cohort. Based on PANoptosis-related genes, an integrated risk signature was constructed to provide a roadmap for patient stratification and predict HCC patient's prognosis. The patients with the higher PANRG-score may carry a dismal survival and relatively low immune infiltration, but a potential better immunotherapy response. Therefore, future HCC therapy perspectives should emphasize the setting of PANoptosis to achieve a personalized, practicable and effective therapeutic regimen.
EEG feature selection method based on maximum information coefficient and quantum particle swarm
Authors: Chen Wan , Cai Yanping , Li Aihua , Su Yanzhao , Jiang Ke 
Published: September 2023

AbstractTo reduce the dimensionality of EEG features and improve classification accuracy, we propose an improved hybrid feature selection method for EEG feature selection. First, MIC is used to remove irrelevant features and redundant features to reduce the search space of the second stage. QPSO is then used to optimize the feature in the second stage to obtain the optimal feature subset. Considering that both dimensionality and classification accuracy affect the performance of feature subsets, we design a new fitness function. Moreover, we optimize the parameters of the classifier while optimizing the feature subset to improve the classification accuracy and reduce the running time of the algorithm. Finally, experiments were performed on EEG and UCI datasets and compared with five existing feature selection methods. The results show that the feature subsets obtained by the proposed method have low dimensionality, high classification accuracy, and low computational complexity, which validates the effectiveness of the proposed method.
Physical function and mental health trajectories in COVID-19 patients following invasive mechanical ventilation: a prospective observational study
Authors: Yamamoto Hiromasa , Tanaka Shinya , Kasugai Daisuke , Shimizu Miho , Tsuchikawa Yohei , Hori Yuto , Fugane Yuki , Inoue Takayuki , Nagaya Motoki , Omote Norihito , Higashi Michiko , Yamamoto Takanori , Jingushi Naruhiro , Numaguchi Atsushi , Goto Yukari , Nishida Yoshihiro 
Published: September 2023

AbstractThis prospective observational cohort study was performed to investigate the physical function and mental health trajectories of novel coronavirus disease 2019 (COVID-19) patients requiring invasive mechanical ventilation (IMV) after discharge from the intensive care unit (ICU). The study population consisted of 64 patients (median age, 60 years; 85.9% male; median IMV duration, 9 days). At ICU discharge, 28.1% of the patients had Medical Research Council (MRC) sum score < 48 points, and prolonged IMV was significantly associated with lower MRC sum score and handgrip strength. Symptoms were similar between groups at ICU discharge, and the symptoms most commonly reported as moderate-to-severe were impaired well-being (52%), anxiety (43%), tiredness (41%), and depression (35%). Although muscle strength and mobility status were significantly improved after ICU discharge, Edmonton Symptom Assessment System score did not improve significantly in the prolonged IMV group. EuroQol five-dimension five-level summary index was significantly lower in the prolonged than short IMV group at 6 months after ICU discharge. We found substantial negative physical function and mental health consequences in the majority of surviving COVID-19 patients requiring IMV, with prolonged period of IMV showing greater negative effects not only immediately but also at 6 months after discharge from the ICU.
Expression of hypoxia-inducible genes is suppressed in altered gravity due to impaired nuclear HIF1α accumulation
Authors: Aboouf Mostafa A. , Thiel Cora S. , Borisov Sergey M. , Tauber Svantje , Bönzli Eva , Schetle Nelli , Ullrich Oliver , Gassmann Max , Vogel Johannes 
Published: September 2023

AbstractExtravehicular activities, the backbone of manned space exploration programs, set astronauts into mild hypoxia. Unfortunately, microgravity aggravates threatening symptoms of hypoxia such as vision impairment and brain edema. Hypoxia-inducible factors (HIFs) sense cellular hypoxia and, subsequently, change the cells’ expression profile instantaneously by rapidly translocating—most likely cytoskeleton-dependently—into the nucleus and subsequently forming transcription complexes with other proteins. We tested the hypothesis that this fundamental process could be altered by sudden changes in gravitational forces in parabolic flights using a newly developed pocket-size cell culture lab that deoxygenizes cells within 15 min. Sudden gravity changes (SGCs 1g–1.8g–0g–1.8g–1g) during hypoxic exposure suppressed expression of the HIF1α-dependent genes investigated as compared with hypoxia at constant 1g. Normoxic cells subjected to SGCs showed reduced nuclear but not cytoplasmatic HIF1α signal and appeared to have disturbed cytoskeleton architecture. Inhibition of the actin-dependent intracellular transport using a combination of myosin V and VI inhibitors during hypoxia mimicked the suppression of the HIF1α-dependent genes observed during hypoxic exposure during SGCs. Thus, SGCs seem to disrupt the cellular response to hypoxia by impairing the actin-dependent translocation of HIF1α into the nucleus.