bluuebunny/crossref_metadata_2025_split huggingface dataset:
Treatment of mild to severe acne with 1726 nm laser: A safe alternative to traditional acne therapies
Authors: Goldberg David J. , Andriessen Anneke , Bhatia Ashish C. , Gold Michael H. , Lewis Amy B. , Lolis Margarita S. , Miller Jason H. , Ros Adriana 
Published: August 2023

AbstractIntroductionAcne is the most common reason for dermatology consultation in adolescents and young adults. Consultation is often delayed despite unsuccessful self‐treatment. Postponing effective treatment places acne sufferers at higher risk for permanent acne scars and post‐inflammatory pigment changes.AimThis review discusses clinical challenges with present therapeutic options for acne treatment and the role of a 1726 nm laser for acne.MethodsCurrent acne treatment guidelines were reviewed. A literature review was conducted for trials of light‐based acne therapy. The selectivity of previous light‐based therapies was reviewed.ResultsAvailable acne therapy is effective, but treatment‐related side effects are common. Acne treatment guidelines do not include recommendations for light‐based treatments. Different types of light‐based treatments have been tried but until now no wavelength specifically targeted sebaceous glands.ConclusionThe 1726 nm laser is safe and effective for treating mild to severe acne in all Fitzpatrick skin types. Acne resolution is apparent within the first month and improves for up to 2 years beyond treatment.
Self‐reported dignity and factors that influence dignity in hospitalised older adults: A cross‐sectional survey
Authors: Fuseini Abdul‐Ganiyu , Rawson Helen , Redley Bernice , Ley Lenore , Mohebbi Mohammadreza , Kerr Debra 
Published: August 2023

AbstractObjectiveThis study examined levels of self‐reported dignity and explored factors expected to influence dignity experienced by older adults during acute hospitalisation in Ghana.BackgroundDignified care has been recognised as inseparable from quality nursing care and maintaining patients' dignity has been highlighted in professional codes of conduct for nurses. However, there is a lack of research on self‐reported dignity and the factors that influence the dignity of older adults during acute hospitalisation in Africa.SettingA large teaching hospital in the northern region of Ghana.ParticipantsHospitalised older adults.MethodsA cross‐sectional survey was used to gather data from a convenience sample of 270 older inpatients, using the Hospitalized Older Adults’ Dignity Scale. Data were analysed using descriptive statistics and stepwise ordinal logistic regression to investigate stratified dignity outcomes. The study was reported following the STROBE checklist.ResultsMore than half of the older adults surveyed reported low to moderate levels of dignity. Demographic characteristics such as age, marital status, religious status, occupation, level of education and type of hospital ward did not show any significant associations with dignity levels. However, there was a significant association found between dignity levels and sex and the number of hospitalisations.ConclusionMost older adults in a Ghanian hospital experienced loss of dignity during their acute hospitalisation. Male older adults reported higher dignity levels during acute hospitalisation than their female counterparts. Further, older adults who were admitted to hospital for the second time reported less dignity compared to those admitted three or more times.Relevance to clinical practiceThe results emphasise the importance of healthcare professionals having the necessary knowledge and skills to provide gender‐sensitive care, which ultimately promotes the dignity of all patients. Additionally, the results underscore the urgency of implementing measures that guarantee patients' dignity during all hospital admissions.Patient or public contributionSurvey questionnaires were completed by hospitalised older adults at the study setting.
Does the timing of neuraxial analgesia initiation in elective induction of multiparous women prolong the duration of delivery?
Authors: Mukai Yuki , Takita Hiroko , Tokunaka Mayumi , Odaki Chihiro , Kato Rie , Hosokawa Yuki , Matsuoka Ryu , Sekizawa Akihiko 
Published: August 2023

AbstractAimTo investigate whether the early initiation of neuraxial analgesia prolongs the duration of electively induced labor in Japanese multiparous women.MethodsThis retrospective study included multiparous term women who underwent elective induction of labor using combined spinal‐epidural analgesia at the Showa University Hospital between October 2018 and March 2021. The participants were divided into two groups: early and late. If neuraxial analgesia was initiated when the cervical dilation was ≤3 cm, the patient was included in the early group. The remaining patients were included in the late group. The obstetric and neonatal outcomes were compared between the two groups. The primary outcome was the duration of delivery. The secondary outcomes were the rates of instrumental and cesarean deliveries.ResultsTwo hundred and ninety‐seven women (early group = 139, late group = 158) were included in the analysis. The duration of the first stage of labor did not differ significantly between the early and late groups (median: 232 vs. 260 min, p = 0.35). Similarly, there was no significant difference in the duration of the second stage (37 vs. 40 min, p = 0.20). Moreover, the rates of instrumental and cesarean deliveries did not differ significantly between the groups, and the neonatal outcomes were comparable.ConclusionEarly initiation of neuraxial analgesia in the elective induction of parous Japanese women did not prolong the duration of delivery. Our results suggest that neuraxial analgesia may be initiated whenever a parturient desires it.
Copolymer liquid embolization of dural arteriovenous fistulas: A 20‐year single‐center experience
Authors: Voldřich Richard , Charvát František , Netuka David 
Published: August 2023

AbstractBackground and PurposeDural arteriovenous fistulas (DAVFs) with cortical venous drainage (CVD) carry significant risks of cerebral ischemia and intracranial hemorrhage. Endovascular treatment (EVT) using Onyx, a copolymer‐based liquid embolic material, has become the preferred approach. However, the optimal treatment strategy for anterior cranial fossa DAVFs remains debated.MethodsThis retrospective study analyzed outcomes of EVT for DAVFs in a single center from 2002 to 2023. Patient data including demographics, clinical status, angiographic findings, embolization techniques, and outcomes were recorded. The results of the anterior fossa malformations were analyzed separately afterward.ResultsA total of 195 DAVFs were included in the study. The most common presenting symptom was hemorrhage (41%), most fistulas were located in the transverse and sigmoid sinus region (48%), and the majority of DAVFs had direct CVD (78%). Transarterial embolization with Onyx was the preferred treatment strategy in majority of cases (92%). Overall, 94% of patients showed improvement or stability on the modified Rankin Scale. Two patients died due to rebleeding after partial DAVF embolization. Onyx demonstrated higher immediate complete occlusion rate compared to other embolic materials (88% vs. 35%). Overall, 91% of fistulas were closed at the last follow‐up. Ten anterior fossa DAVFs were treated, resulting in clinical improvement and complete occlusion in all cases.ConclusionBased on the results of our study, we believe that a cure of DAVFs, including those in the anterior fossa, can be achieved in more than 90% of cases through transarterial Onyx embolization, given long‐term clinical experience.
Isometric tongue endurance and incomplete laryngeal vestibule closure in Parkinson's disease
Authors: da Costa Flavia Pereira , Casseb Raphael Fernandes , de Lima Daniella Priscila , Ponsoni Adriana , Guimarães Rachel Paes , Mourão Lucia Figueiredo 
Published: August 2023

AbstractBackgroundDysphagia is a common symptom of Parkinson's disease (PD). A delay in laryngeal vestibule closure (LVC) and a reduction in tongue pressure, may affect swallowing safety and increase the risk of pulmonary aspiration.ObjectiveTo verify the relationship between tongue pressure and airway protection in PD patients: (1) comparing tongue pressure measures and physiological events in the pharyngeal phase of swallowing between PD and controls and (2) analysing the association between tongue pressure and LVC in the PD group.MethodsTwenty‐three patients with idiopathic PD (64.9 years) and 24 healthy controls (64.1 years) participated in this study. All participants underwent the following procedures to verify tongue pressure measurements using the Iowa Oral Performance Instrument: maximum anterior and posterior pressure, isotonic and isometric tongue endurance and anterior and posterior tongue pressure during saliva swallowing. To verify swallowing safety, videofluoroscopic swallowing studies focusing on the pharyngeal phase were performed based on the MBSImP protocol.ResultsCompared to healthy controls, PD exhibited a statistically significant decline in tongue pressure tasks: posterior maximum pressure, isotonic endurance, anterior and posterior isometric endurance and tongue pressure during posterior swallowing. Patients with PD had worse pharyngeal scores, including LVC scores, than controls. PD and incomplete LVC had lower anterior isometric endurance scores when compared to those with complete LVC.ConclusionPD with incomplete LVC scored lower in the anterior isometric endurance task. We observed a potential clinical use of this task for the assessment and management of dysphagia in patients with PD.
Differentiation of T cells producing interleukin‐17 (Th17) against the background of exogenous melatonin during pregnancy
Authors: Glebezdina Natalya Sergeevna , Nekrasova Irina Valerievna , Olina Anna Alexandrovna , Sadykova Gulnara Kamilyevna , Kuklina Elena Michajlovna 
Published: August 2023

AbstractThe population of T lymphocytes producing IL‐17 (Th17) plays a dual role during pregnancy and its activity is tightly controlled during this period. One of the factors involved in this process may be the pineal hormone melatonin, which can effectively regulate this T cell population. Here we have shown that exogenous melatonin in pharmacological concentrations is able to enhance the differentiation of Th17 cells of pregnant women in vitro. The stimulatory effects of melatonin were limited to in the first trimester of pregnancy and were apparently mediated by both membrane and nuclear melatonin receptors. Since exogenous melatonin is currently considered as a promising drug in solving various problems associated with reproduction, it is necessary to take into account its immunoregulatory effects.
Changing the geographic scope of collaboration: Implications for product innovation novelty and commercialization
Authors: Kesidou Effie , Love James H. , Ozusaglam Serdal , Wong Chee Yew 
Published: August 2023

AbstractPrior research points out the benefits of external collaboration for innovation, yet little is known of: (a) the changes in the scope of external collaboration over time (i.e., firms increasing, seeking stability, or decreasing the geographic scope of their collaboration), and (b) how such changes in the geographic scope of collaboration affect product innovation novelty and commercialization. Here, we build on organizational learning theory, with the objective of exploring how changes in the geographic scope of collaboration over time affect the novelty of product innovation and its commercial success. Econometric analysis of a large panel of UK firms reveals three novel findings: First, while stability in the geographic scope of collaboration is common, there is a marked incidence of change, that is, firms are increasing or decreasing the geographic scope of collaboration. Second, while moving toward more geographically distant collaboration is beneficial mostly for radical innovation, maintaining stability in the geographic scope of collaboration is particularly beneficial for incremental innovation. Third, we demonstrate that becoming less international in the geographic scope might be beneficial for innovation commercialization. Finally, we identify six pathways to geographic collaboration that map to innovation outcomes.
Autumn grass treated with a hydrolysable tannin extract versus lactic acid bacteria inoculant: Effects on silage fermentation characteristics and nutritional value and on performance of lactating dairy cows
Authors: Van den Bossche Tine , Goossens Karen , Haesaert Geert , Wambacq Eva , Vandaele Leen , De Boever Johan L. 
Published: August 2023

AbstractHydrolysable tannins (HT) show potential as silage additive for autumn herbage silages, high in (rumen degradable) protein, as they may reduce proteolysis. Additionally, they have abilities to form pH‐reversible tannin–protein complexes, non‐degradable in the rumen but degradable in the abomasum and intestines of ruminants. Therefore they can improve milk N efficiency and shift N excretions from urine to faeces, possibly mitigating the environmental impact of ruminants. In this study, two small bunker silos were filled with autumn grass. One was treated with 20 g/kg DM HT extract (TAN) (TannoSan‐L), the other with 8 mg/kg DM inoculant containing lactic acid bacteria (INO) (Bonsilage Fit G). Secondly, micro‐silos (2.75 L) were filled with four treatments; (1) grass without additive (CON) (n = 5); (2) TAN (n = 5); (3) INO (n = 5); and (4) TAN + INO (n = 5). The bunker silos were used in a cross‐over feeding experiment with periods of 4 weeks involving 22 lactating Holstein cows (average ± SD: 183 ± 36.3 days in milk, 665 ± 71.0 kg body weight, and 33.8 ± 3.91 kg/day milk yield). The HT dose was insufficient to reduce proteolysis or alter chemical composition and nutritional value in the micro‐ and bunker silages. Including grass silage added with TAN (3.2 g HT/kg DM) in the diet, did not affect feed intake nor fat and protein corrected milk yield in comparison to feeding the grass silage added with INO in a similar diet. The TAN‐fed cows had an increased faecal N excretion and decreased apparent total‐tract N and organic matter digestibility, but no improvement in the cows’ N utilization could be confirmed in milk and blood urea levels. Overall, feeding an autumn grass silage treated with 20 g/kg chestnut HT extract did not affect the performance of dairy cows in comparison to feeding an autumn grass silage treated with a lactic acid bacteria inoculant.
Kidney transplantation in people living with human immunodeficiency virus: An overview of the Australian experience
Authors: McMullen Lucy , Drak Douglas , Basu Gopal , Coates P. Toby , Goodman David J. , Graver Alison , Isbel Nicole , Lim Wai H. , Luxton Grant , Sciberras Frederika , Toussaint Nigel D. , Wong Germaine , Gracey David M. 
Published: August 2023

AbstractKidney transplantation in people living with HIV (PLWHIV) is occurring with increasing frequency. Limited international data suggest comparable patient and graft survival in kidney transplant recipients with and without HIV. All PLWHIV aged ≥18 years who received a kidney transplant between 2000 and 2020 were identified by retrospective data initially extracted from Australia and New Zealand Dialysis and Transplant Registry (ANZDATA), with additional HIV‐specific clinical data extracted from linked local health‐care records. Twenty‐five PLWHIV and kidney failure received their first kidney transplant in Australia between January 2000 and December 2020. Majority were male (85%), with median age 54 years (interquartile range, IQR 43–57). Focal segmental glomerulosclerosis was the most common primary kidney disease (20%), followed by polycystic kidney disease (16%). 80% of patients underwent induction with basiliximab and none with anti‐thymocyte globulin (ATG). Participants were followed for median time of 3.5 years (IQR 2.0–6.5). Acute rejection occurred in 24% of patients. Two patients lost their allografts and three died. Virological escape occurred in 28% of patients, with a maximum viral load of 190 copies/mL. In conclusion, kidney transplantation in PLWHIV in Australia is occurring with increasing frequency. Acute rejection is more common than in Australia's general transplant population, but this does not appear to be associated with higher rates of graft failure or mortality out to four years.
Laparoscopic observations of adhesions between peritoneal dialysis catheters and intraperitoneal organs: A retrospective, observational study
Authors: Maeda Takuya , Io Hiroaki , Hara Kazuaki , Nakata Junichiro , Ishizaka Masanori , Shimizu Yuki , Shirotani Yuka , Fukuzaki Haruna , Suzuki Yusuke 
Published: August 2023

AbstractLaparoscopy provides extensive data for the decannulation of a peritoneal dialysis catheter and is being increasingly used to diagnose encapsulating peritoneal sclerosis. However, there are few reports on the methods of decannulation of peritoneal dialysis catheters. In this study, we examined the laparoscopic findings and postoperative complications of patients undergoing peritoneal dialysis catheter removal. A total of 119 laparoscopic decannulations of peritoneal dialysis catheters were performed between 2003 and 2018 at the Juntendo University Hospital and Juntendo University Nerima Hospital. Laparoscopy was performed during peritoneal dialysis catheter removal by a gastrointestinal surgeon. Patient characteristics such as age, sex, duration of peritoneal dialysis, history of peritonitis and age at the time of peritoneal dialysis termination were assessed. Of these 119 cases, 19 (16.0%) showed adhesion between the peritoneal dialysis catheter and intraperitoneal organs. There were 13 (10.9%) cases involving a tangled omentum, 4 (3.4%) cases involving the small intestine and 2 (1.7%) cases of adhesions extending from the bowels to the abdominal wall. No postoperative complications were associated with the laparoscopic surgery. In these cases, blind decannulation of the peritoneal dialysis catheter may result in injury to the gastrointestinal tract in patients with adhesions. Therefore, we need to pay attention to adhesions between peritoneal dialysis catheters and intraperitoneal organs, and laparoscopy could be a valuable tool in detecting such adhesions and ensuring patient safety.
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Wound‐response jasmonate dynamics in the primary vasculature
Authors: Morin Hugo , Chételat Aurore , Stolz Stéphanie , Marcourt Laurence , Glauser Gaëtan , Wolfender Jean‐Luc , Farmer Edward E. 
Published: August 2023

Summary

The links between wound‐response electrical signalling and the activation of jasmonate synthesis are unknown. We investigated damage‐response remodelling of jasmonate precursor pools in the Arabidopsis thaliana leaf vasculature.

Galactolipids and jasmonate precursors in primary veins from undamaged and wounded plants were analysed using MS‐based metabolomics and NMR. In parallel, DAD1‐LIKE LIPASEs (DALLs), which control the levels of jasmonate precursors in veins, were identified.

A novel galactolipid containing the jasmonate precursor 12‐oxo‐phytodienoic acid (OPDA) was identified in veins: sn‐2‐O‐(cis‐12‐oxo‐phytodienoyl)‐sn‐3‐O‐(β‐galactopyranosyl) glyceride (sn‐2‐OPDA‐MGMG). Lower levels of sn‐1‐OPDA‐MGMG were also detected. Vascular OPDA‐MGMGs, sn‐2‐18:3‐MGMG and free OPDA pools were reduced rapidly in response to damage‐activated electrical signals. Reduced function dall2 mutants failed to build resting vascular sn‐2‐OPDA‐MGMG and OPDA pools and, upon wounding, dall2 produced less jasmonoyl‐isoleucine (JA‐Ile) than the wild‐type. DALL3 acted to suppress excess JA‐Ile production after wounding, whereas dall2 dall3 double mutants strongly reduce jasmonate signalling in leaves distal to wounds.

LOX6 and DALL2 function to produce OPDA and the non‐bilayer‐forming lipid sn‐2‐OPDA‐MGMG in the primary vasculature. Membrane depolarizations trigger rapid depletion of these molecules. We suggest that electrical signal‐dependent lipid phase changes help to initiate vascular jasmonate synthesis in wounded leaves.
Citizen science approaches to crowdsourcing food environment data: A scoping review of the literature
Authors: Monaghan Jacqueline , Backholer Kathryn , McKelvey Amy‐Louise , Christidis Rebecca , Borda Ann , Calyx Cobi , Crocetti Alessandro , Driessen Christine , Zorbas Christina 
Published: August 2023

SummaryGlobally, the adoption and implementation of policies to improve the healthiness of food environments and prevent population weight gain have been inadequate. This is partly because of the complexity associated with monitoring dynamic food environments. Crowdsourcing is a citizen science approach that can increase the extent and nature of food environment data collection by engaging citizens as sensors or volunteered computing experts. There has been no literature synthesis to guide the application of crowdsourcing to food environment monitoring. We systematically conducted a scoping review to address this gap. Forty‐two articles met our eligibility criteria. Photovoice techniques were the most employed methodological approaches (n = 25 studies), commonly used to understand overall access to healthy food. A small number of studies made purpose‐built apps to collect price or nutritional composition data and were scaled to receive large amounts of data points. Twenty‐nine studies crowdsourced food environment data by engaging priority populations (e.g., households receiving low incomes). There is growing potential to develop scalable crowdsourcing platforms to understand food environments through the eyes of everyday people. Such crowdsourced data may improve public and policy engagement with equitable food policy actions.
Extended brief interventions for weight management and obesity prevention in children: A rapid evidence review
Authors: Grey Elisabeth , Griffin Tania , Jolly Kate , Pallan Miranda , Parretti Helen , Retzer Ameeta , Gillison Fiona 
Published: August 2023

SummaryUptake of child weight management (CWM) support is typically low, and services are not available in all areas. Extended brief interventions (EBIs) have been proposed as an affordable way to provide enhanced support, at a level between one‐off brief advice and intensive CWM programs. This rapid systematic review sought to synthesize evidence on the efficacy of EBIs for weight management and obesity prevention in children (2–18 years). Embase and Web of Science were searched from January 2012 to January 2022. Nineteen studies, reporting on 17 separate EBIs, were included. The quality of studies was variable, and the EBIs were heterogeneous. The majority of EBIs (n = 14) were based on motivational interviewing. Five of the included studies reported significant improvements in parent or child determinants of health behavior change. However, robust measures of behavioral determinants were rarely used. No studies reported significant positive effects on child weight. No clear patterns in outcomes were identified. There is currently insufficient evidence for EBIs to be adopted as part of CWM services. To improve the evidence base, EBIs that are currently being implemented by local health services, should be evaluated to establish the most effective content, how it should be delivered, and by whom.
Creation, intersubjectivity and the novel: Unamuno on life in Cómo se hace una novela
Authors: Andersen Katrine Helene 
Published: August 2023

AbstractThis article shows that, in Miguel de Unamuno, both philosophy and literature contribute to an intellectual project that has to do with life. I will argue that Unamuno, in Cómo se hace una novela, presents a philosophy of life that understands human life as an intersubjective creation. We create life in the same way we do a novel, that is to say, through intersubjective dialectics. Cómo se hace una novela reveals an idea about life in which our ontological potential manifests itself in the novelistic creation and where the text becomes an intersubjective common ground.