bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Chemistry Triangle-Based Multimedia to Build A Good Impression: A Design-Based Research
Authors: Sausan Inas , Saputro Sulistyo , Indriyanti Nurma Yunita 
Published: March 2023

<p>Science teachers need to pay attention when introducing chemistry to junior high school students hence they don't have low perceptions of chemistry. Multimedia which based on the chemistry triangle can be a solution in helping teachers explains the relationships among macroscopic, sub-microscopic, and symbolic level of chemistry so students can understand the scientific contents better and have a good perceptions. This research aimed to develop a chemistry triangle-based multimedia to build a good impression on junior high school students about chemistry. The design of chemistry triangle-based multimedia was developed through a design-based research (DBR). The participants in the research were three schools of seventh-grade students in Pekalongan Regency, Indonesia. The data were collected through interviews, observations, questionnaires, and tests. The results of this research were in the form of the complete cycles of DBR carried out to produce a chemistry triangle-based multimedia that meets the criteria in helping teachers introduce chemistry in a way that is more easily accepted by students and gives a positive impression about chemistry. This article describes the four phases of the DBR process in the development of chemistry triangle-based multimedia.</p><p> </p>
Surgical Treatment of Severe Sprengel's Deformity
Authors: Li Haichong , Zhang Hanwen , Zhang Xuejun , Yao Ziming , Gao Jingchun , Liu Haonan , Guo Dong , Zhang Wenyan 
Published: March 2023

Update
This article was updated on May 19, 2023, because of a previous error. One of the authors, Ziming Yao, MD, was accidently left off of the article pdf.
An erratum (JBJS Case Connect. 2023;13[2]:e22.00648ER) has been published for this article.

Case:
An adolescent girl who presented with obviously impaired shoulder abduction due to untreated severe Sprengel's deformity underwent deformity correction surgery. Intraoperative neuromonitoring was used to warn of potential brachial plexus injury during a modified Woodward procedure. At 3-month follow-up, range of shoulder abduction had improved significantly.

Conclusion:
Sprengel's deformity is a rare congenital shoulder deformity, and the Woodward procedure could cause nerve injury in patients with severe Sprengel's deformity. Neuromonitoring can be performed intraoperatively to avoid brachial plexus injury.
Downlink Channel Performance Assessment of Time Division Duplex (TDD) and Frequency Division Duplex (FDD) for multiple Transmission Modes of Fifth Generation Communication System
Authors: Saxena Ankit 
Published: March 2023

Abstract
The requirement of the wireless network is increasing with the developments in every field of society. As it helps to use contactless controls and communications with different applications. From the fifth generation and beyond, the need of wireless networks is to fulfil the capacity requirement and offered better connectivity between peer entities. To offer high throughput within the wireless network, beamforming is one among the optimum solutions that provides better connectivity and bandwidth among peer entities. In the work, we assessed the wireless capacity of beamforming wireless network using the Frequency Division Duplexing (TDD) and Time Division Duplexing (TDD) type for multiple Transmission Modes (TM) under different radio conditions. We modify the channel properties with respect to varying the Signal to Noise Ratio (SNR) and measured the performance of both systems independently in terms of throughput, and Block Error for both the duplexing using quantitative and ratio analysis. Further, we conclude that the beamforming for higher TMs offered high throughput in best to worst channel conditions.
Privacy Prevention and Nodes Optimization, Detection of IoUT based on Artificial Intelligence
Authors: Gaur Rajkumar , Prakash Shiva 
Published: March 2023

Abstract

Transportation, temperature control, and the production of pharmaceuticals all rely on 71 percent of the Earth's surface, which is covered by water. Valuable things, including minerals, metals, corals, and coral reefs, can be identified with the help of the IoUT, among other applications. One of the crucial uses is in preventing damage caused by natural disasters. The IoT boosted concepts for a new undersea network (IoUT). Underwater networks have many drawbacks, including a lack of dependability, limited bandwidth, long propagation delays, high processing demands, high energy costs, and node detection with secure communication. Real-time, secure data communication is a significant area of research for us, along with node identification and dynamic network configuration. IoUT faces severe obstacles in the form of these issues. Our strategy involves a dynamic graph for network design, an AFA algorithm based on AI for node recognition, and ECC for a secure communication mechanism. In order to increase discretion and provide the undersea network with adequate robust security.
Research on 5G millimeter wave dynamic rain attenuation and adaptive modulation coding scheme
Authors: yang ruike , Jinxiu Han , xia gao , Linlin Liang , Fuping Wu 
Published: March 2023

Abstract

In order to study the effect of rainfall on 5G millimeter-wave (MMW) communication, a new modified MMW dynamic rain attenuation time series model based on the Weibull distribution rainfall model and the EMB time series model is proposed. The analysis for the subtropical Haikou 78GHz rainfall link performance shows that the simulating time series by newly modified model can effectively characterize the dynamic and statistical properties of MMW rain attenuation. According to this model, an adaptive modulation coding scheme (MCS) is induced which can be applied to rainfall fading links. On the 78G MMW rainfall link, the BER, the spectral efficiency are analyzed. The MCS transform algorithm is presented. Through the simulation analysis, the adaptive MCS for mitigating the effects of rain attenuation is recommended. The scheme can effectively mitigate the effect of rainfall on the MMW link and improve the system spectrum utilization and availability.
Lacticaseibacillus rhamnosus GG encapsulation with milk proteins-based matrix preserves SpaCBA pili integrity after spray-drying and improves resistance to subsequent in vitro gastrointestinal digestion
Authors: GAIANI claire , Morais Raphael Dos Santos , BORGES Frederic , AMARA Sawsan , Mohamed Loubiana Cvetkovska-Ben , SEILER Aurélie , Burgain Jennifer 
Published: March 2023

Abstract

Lacticaseibacillus rhamnosus GG, or LGG, is one of the most studied probiotic bacterium worldwide. The health benefit properties of LGG are mainly ensured by SpaCBA pili, which are polymeric proteins located at the cell surface. These pili confer the ability to interact with the surrounding environment and notably to adhere to intestinal cells mainly through interactions with mucin glycoproteins. For an expected probiotic effect, cell viability is an essential parameter. Nevertheless, the stability and the integrity of the pili is of paramount importance, from the conservation process of bacteria to the subsequent gastrointestinal digestion. One way to preserve bacterial viability is to encapsulate them within a matrix made of milk proteins where bacteria-matrix interactions occur and play an essential role. In the present study, nanoDSF and MST analyses revealed the remarkable thermal and detergent stability, respectively, of purified native SpaCBA pili and of the corresponding recombinant pilins. Crosslinking experiments have shown that SpaC can directly interact with β-lactoglobulin, the most abundant whey protein in the matrix with a dissociation constant (Kd) around 100 µM. The preservation of SpaCBA pili on protected LGG after spray drying was evidenced. Finally, the improved survival rate of protected LGG by resisting to simulated human digestion was shown compared to unprotected LGG. This study demonstrated that LGG encapsulation in a relevant matrix is mandatory to preserve bacteria viability and functionality after spray drying and to guarantee its preservation during the subsequent human digestion.
How the Experience of California Wildfires Shapes Twitter Climate Change Framings
Authors: Ko Jessie W. Y. , Ni Shengquan , Taylor Alexander K. , Chen Xiusi , Huang Yicong , Kumar Avinash , Alsudais Sadeem , Wang Zuozhi , Liu Xiaozhen , Wang Wei , Li Chen , Hopfer Suellen 
Published: March 2023

Abstract
Climate communication scientists search for effective message strategies to engage the ambivalent public in support of climate advocacy. The personal experience of wildfire is expected to render climate change impacts more concretely, pointing to a potential message strategy to engage the public. This study examined Twitter discourse related to climate change during the onset of 20 wildfires in California between years 2017-2021. We content analyzed tweets geographically and temporally proximal to the occurrence of wildfires to discover framings and examined how mean frequencies in climate framings changed before and after fires. Results identified three predominant climate framings: making explicit links between wildfire and climate change, suggesting climate actions, and attributing climate change to adversities besides wildfires. Mean tweet frequencies linking wildfire with climate change and attributing adversities increased significantly after the onset of fire while urging climate action tweets did not. Temporal analysis of tweet frequencies of tweets linking wildfires to climate change showed that discussion increased after the onset of a fire but persisted typically no more than one to two weeks. External real-world events happening simultaneously during wildfires also triggered climate discussions. Our findings contribute to identifying how the personal experience of wildfire shapes Twitter discussion related to climate change, and how these narratives change over time before and after wildfires, leading to insights into critical time points after wildfire for implementing message strategies to increase public engagement on climate change impacts and policy.
Improving lake chlorophyll-a interpreting accuracy by combing spectral and texture features of remote sensing
Authors: Yang YuFeng , Zhang Xiang , Gao Wei , Zhang Yuan , Hou XiKang 
Published: March 2023

Abstract

Cyanobacterial blooms in lakes fueled by increasing eutrophication have garnered global attention, and high-precision remote sensing retrieval of chlorophyll-a (Chla) is essential for monitoring the blooms. Previous studies have focused on the spectral features extracted from remote sensing images and their relationship with chlorophyll-a concentrations in water bodies, ignoring the texture features in remote sensing images which is beneficial to improve interpreting accuracy. This study explores the texture features in remote-sensing images. It proposes a retrieval method for estimating lake Chla concentration by combining spectral and texture features of remote sensing images. Remote sensing images from Landsat 5, and 8 were used to extract NIR-Red, GREEN-BLUE, MNDWI, and KIVU bands ratio. The gray-level co-occurrence matrix (GLCM) of remote sensing images was used to obtain a total of 8 texture features; then three texture indices were calculated using texture features. Finally, a random forest regression was used to establish a retrieval model of in-site Chla concentration from texture and spectral index. Results showed that texture features are significantly correlated with lake Chla concentration, and they can reflect the temporal and spatial distribution change of Chla. The retrieval model combining spectral and texture indices has better performance (R2 = 0.801, RMSE = 16.0 µg·L− 1) than the model without texture features(R2 = 0.746, RMSE = 16.2 µg·L− 1). The proposed model performance varies in different Chla concentration ranges and is excellent in predicting higher concentrations. This study evaluates the potential of incorporating texture features of remote sensing images in lake water quality estimation and provides a novel remote sensing method to better estimate lake Chla concentration.
Gait characteristics of individuals with incomplete cervical spinal cord injury by the wearable gait analysis system
Authors: Tanaka Yousuke , Kadoya Ken , Harmon Satoko Matsumoto , Kikuchi Jun , Nakamura Sachiko , Sato Kiichi , Suda Kota 
Published: March 2023

Abstract
Study design: Quantitative cross-sectional study.
Objectives: Individuals with incomplete cervical spinal cord injury (ICSCI) have balance function. However, the details of the correlation between spatiotemporal gait variables and balance function in ICSCI people remain to be clarified. The objectives of this study were to investigate (1) the difference in gait performance between individuals with ICSCI and control participants, and (2) the correlation between the gait variables and walking speed or the balance function in the ISCI group.
Setting: Hokkaido Spinal Cord Injury Center, Japan.
Methods: Nineteen CSCI individuals who can walk without any devices or assistance and nine control participants performed a 15m walking test and/or the mini-BESTest. The wearable sensor system (Physilog®5) were attached on feet for the analysis of the spatiotemporal gait variables.
Results: While walking speed was not significantly different between the groups, the phase times of loading, foot-flat, and pushing were significantly different. The results of correlation and multivariate regression analysis revealed the loading and foot-flat phases were associated with the balance function, and the pushing phase was an important factor in producing propulsion.
Conclusion: The findings of the present study suggest that individuals with CSCI increased dynamic stability rather than propulsion during the stance phase to achieve a comparable walking speed to healthy individuals.
Identification of key genes associated with age difference in osteoarthritis under weight loss intervention: based on bioinformatics analysis
Authors: Luo Ziyu , Sun Yuyan , Ling Huixian , Zhou Haiqi , Wu Sha , Ngo Namanh , Zhang Changjie , Shen Hongwei , Kong Ying 
Published: March 2023

Abstract
Background
The aim of this study was to identify the key genes that changed after weight loss intervention in patients with osteoarthritis (OA) at different ages by identifying differentially expressed genes (DEGs).
Methods
GSE114007 and GSE158850 gene expression data were downloaded from Gene Expression Omnibus (GEO) database, DEGs were found using R software, and overlapping DEGs were obtained. The results were screened and validated by receiver operating characteristic (ROC) curve and boxplot. The immune cell infiltration and Gene Set Enrichment Analysis (GSEA) of the two genes were analyzed.
Results
There were two overlapping DEGs between OA dataset with the young group of obese men who had weight loss intervention, after screening, MAFB was remaining. There were two overlapping DEGS with the aged group, and the remaining one was BPGM. The results of immunological cell infiltration showed that these two genes were associated with macrophages. Enrichment analysis showed that MAFB was associated with the “Linoleic acid metabolism” pathway in both datasets.
Conclusion
MAFB and BPGM may be the therapeutic targets for obese patients with OA, and may be the indicators for evaluating the effectiveness of intervention.
South Asian women’s lived experiences of health care after disclosure of family violence: A qualitative meta-synthesis review
Authors: Baloch Surriya , McLindon Elizabeth , Hameed Mohajer , Hegarty kelsey 
Published: March 2023

Abstract

Introduction: Given the high prevalence of family violence (FV) amongst South Asian women, the experiences and expectations of addressing FV in health care settings is of policy, practice and research interest. Whilst FV is shaped and influenced by various interconnected sociodemographic and cultural factors, it can be addressed in health care settings through identification and response. Methods: This review utilized a systematic methodology to search nine databases up to July 2022. A total of 6,685 records were screened by two reviewers independently based on a priori inclusion and exclusion criteria. A thematic analytical approach guided integration of findings from thirteen qualitative studies. Results: Thematic synthesis of the articles generated three themes (1) I was afraid to share, (2) They just walk away, (3) Understand and listen to my pain. These themes represented the perspectives, feelings, and expectations of South Asian women survivor participants living in South Asia as well as migrant South Asian women. Cultural factors and social obstacles may prevent South Asian women from seeking and using appropriate support services. Additional barriers may include health care providers’ reluctance to address FV with South Asian women because of a lack of cultural knowledge and/or appropriate methods to address FV. South Asian women participants reflected they want health care providers to understand them, acknowledge their discomfort, and provide culturally appropriate strategies and solutions. Conclusion: It is highly recommended that policymakers and health-care providers continue to be mindful of the social and cultural challenges which face South Asian women who experience family violence.
Inhibition of DNMT3B expression in activated hepatic stellate cells overcomes chemoresistance in the tumor microenvironment of hepatocellular carcinoma
Authors: Song Yeonhwa , Kim Namjeong , Heo Jinyeong , Shum David , Heo Taemoo , Seo Haeng Ran 
Published: March 2023

Abstract
Hepatocellular carcinoma (HCC) is a complex disease associated with a plethora of environmental and genetic/hereditary causative risk factors, more so than other oncological indications. Additionally, patients with HCC exhibit fibrosis, cirrhosis, and liver-related disease. This complicated etiology can affect the disease course and likely contributes to its poor prognosis. In this study, we aimed to improve HCC therapy by evaluating combination treatment using anti-cancer and anti-fibrosis drugs via identification of novel anti-fibrosis drugs. We performed high-throughput screening of 10,000 compounds to identify hepatic fibrosis inhibitors through morphometry analysis of multicellular hepatic spheroid (MCHS) models and identified CHIR-99021 as a candidate anti-fibrotic drug. Treatment with CHIR-99021 induced loss of cell-cell interactions and suppression of extracellular matrix-related protein expression via reprogramming of hepatic stellate cell (HSC) activation in MCHSs. In particular, CHIR-99021 regulated DNMT3B expression only in activated HSCs. Moreover, CHIR-99021 markedly improved the efficacy of sorafenib in HCC- multicellular tumor spheroids in vitro and through induction of apoptosis by decreasing DNMT3B expression in vivo. In summary, these findings suggest that targeting HSC reprogramming by attenuation of DNMT3B expression in the tumor environment might represent a promising therapeutic strategy for liver fibrosis and HCC.
Engineering of the temperate Burkholderia phage Milagro for use as a therapeutic
Authors: Yao Guichun , Le Tram , Korn Abby , Peterson Hannah , Liu Mei , Gonzalez Carlos , Gill Jason 
Published: March 2023

Abstract
The Burkholderia cepacia complex (Bcc) causes life-threatening respiratory tract infections in persons with cystic fibrosis (CF). In CF patients, end-stage pulmonary disease often requires lung transplantation. However, pre-transplant colonization with antibiotic-resistant strains of Burkholderia is predictive of poor post-transplant outcomes. To address this issue, phage therapy has been proposed as a treatment of multiple drug resistant bacterial infections. However, the majority of characterized Bcc phages are temperate and are therefore unsuitable for phage therapeutics. Moreover, the few virulent (obligately lytic) phages that have been isolated have extremely limited host ranges, usually restricted to the original host used for isolation. To overcome this limitation, we have engineered a virulent, broad-host range derivative of the temperate phage Milagro, designated Milagro vir gp20:Milo Δcl. The engineered phage has a mutation in the predicted lysogenic repressor binding site, a deletion of the lysogenic repressor gene, and a fusion of the phage tail fiber with the receptor-binding domain of the broad-host range tailocin (bacteriocin) BceTMilo. Phage Milagro vir gp20:Milo Δcl has a substantially expanded host range and is able to infect multiple Bcc species including B. cenocepacia, B. multivorans, B. gladioli and B. vietnamensis. To establish a platform for phage engineering, a CRISPR/Cas9 system was developed in Burkholderia that system allows for direct gene editing of virulent phage.
Assessment of some urban ornamental plants in southern Iran revealed that they choose one of the two enzymatic or non-enzymatic antioxidants defensive strategies against heavy metals
Authors: Amareh Reza , Kaviani Behzad , Sedaghathoor Shahram , Allahyari Mohammad Sadegh 
Published: March 2023

Abstract
Heavy metals (HMs) are one of the most important environmental contaminants. One of the effective approaches to reduce this contamination is phytoremediation. The concentration of ten heavy metals (HMs) including arsenic (As), cadmium (Cd), chromium (Cr), cobalt (Co), copper (Cu), iron (Fe), lead (Pb), nickel (Ni), tin (Sn), and zinc (Zn) were measured in ten ornamental plants consisting Ficus religiosa, Ficus elastica, Syzygium cumini, Azadirachta indica, Clerodendrom inerme, Conocarpus erectus, Bougainvillea sp., Delonix regia, Dodonaea viscosa, and Phoenix sp. grown in the city of Bushehr, located in southern Iran. The concentration of HMs was determined by ICP-MS. Some physiological parameters (relative leaf water, dry matter, vitamin C, pH, chlorophyll a, b, and total, carotenoid, anthocyanin, total flavonoid, total protein, total soluble carbohydrates, and proline), and antioxidant enzymes [peroxidase (POD) and superoxide dismutase (SOD)] activity were measured. Bougainvillea had greater amount of Zn (61.86 mg/kg D.W.), Cu (45.52 mg/kg D.W.), and Cr (14.71 mg/kg D.W.) than the other HMs. Greatest amount of Co (0.686 mg/kg D.W.), Fe (428.00 mg/kg D.W.), and Ni (6.44 mg/kg D.W.) was obtained in C. erectus. Also, C. inerme had maximum As (0.0087 mg/kg D.W.) and Sn (2.516 mg/kg D.W.). The highest percentage of dry matter (46.03%) in Phoenix, the highest amount of vitamin C (8.50 mg/100 g F.W.), chlorophyll b (7.63 µg/ml), and total flavonoid (3.92 M/g) in S. cumini, and the highest amount of chlorophyll a (14.61 µg/ml), total chlorophyll (21.86 µg/ml), carotenoid (20.83 µg/g F.W.), and anthocyanin (18.81 mg/100 g F.W.) in F. elastica were obtained. The POD activity (1.462 and 1.214 U/g F.W./min) was highest in leaves of C. inerme and F. elastica containing the highest concentrations of As, Sn and Pb, respectively. The SOD activity was high in these two species. Synthesis of osmolytes increased under Co and Sn stresses. D. viscosa was found to contain most total soluble carbohydrates (24.94%) and proline (1.14 µM/g F.W.) concentration compared to other species. The selected plant species followed a defensive strategy (enzymatic or non-enzymatic) against excess of HMs. Overall, shrubs were much more suitable than trees for absorption of HMs, and C. inerme, F. elastica and Bougainvillea are the best plant species in this connection, respectively.