bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ethnic differences in respiratory disease for Native Hawaiians and Pacific Islanders: Analysis of mediation processes in two community samples
Authors: Wills Thomas A. , Kaholokula Joseph Keawe’aimoku , Pokhrel Pallav , Pagano Ian 
Published: August 2023

Objective
The prevalence of asthma and chronic obstructive pulmonary disorder (COPD) is elevated for Native Hawaiians but the basis for this differential is not well understood. We analyze data on asthma and COPD in two samples including Native Hawaiians Pacific Islanders, and Filipinos to determine how ethnicity is related to respiratory disease outcomes.

Methods
We analyzed the 2016 and 2018 Behavioral Risk Factor Surveillance Survey (BRFSS), a telephone survey of participants ages 18 and over in the State of Hawaii. Criterion variables were a diagnosis of asthma or COPD by a health professional. Structural equation modeling tested how five hypothesized risk factors (cigarette smoking, e-cigarette use, second-hand smoke exposure, obesity, and financial stress) mediated the ethnic differential in the likelihood of disease. Age, sex, and education were included as covariates.

Results
Structural modeling with 2016 data showed that Native Hawaiian ethnicity was related to higher levels of the five risk factors and each risk factor was related to a higher likelihood of respiratory disease. Indirect effects were statistically significant in almost all cases, with direct effects to asthma and COPD also observed. Mediation effects through comparable pathways were also noted for Pacific Islanders and Filipinos. These findings were replicated with data from the 2018 survey.

Conclusions
Native Hawaiian and Pacific Islander ethnicity is associated with greater exposure to five risk factors and this accounts in part for the ethnic differential in respiratory disease outcomes. The results support a social-ecological model of health disparities in this population. Implications of the findings for preventive interventions are discussed.
A Tissue Systems Pathology Test Outperforms the Standard of Care Variables in Predicting Progression in Patients with Barrett’s Esophagus
Authors: Davison Jon M. , Goldblum John R. , Duits Lucas C. , Khoshiwal Amir M. , Bergman Jacques J. , Falk Gary W. , Diehl David L. , Khara Harshit S. , Smolko Christian , Arora Meenakshi , Siegel Jennifer J. , Critchley-Thorne Rebecca J. , Thota Prashanthi N. 
Published: August 2023

ABSTRACT

Background:
Objective risk stratification is needed for patients with Barrett’s esophagus (BE) to enable risk-aligned management to improve health outcomes. This study evaluated the predictive performance of a tissue systems pathology test (TissueCypher, TSP-9) versus current clinicopathologic variables in a multi-center cohort of BE patients.

Methods:
Data from 699 BE patients from five published studies on the TSP-9 test was evaluated. 509 patients did not progress during surveillance, 40 were diagnosed with HGD/EAC within 12 months, and 150 progressed to HGD/EAC after 12 months. Age, sex, segment length, hiatal hernia, original and expert pathology review diagnoses, and TSP-9 risk classes were collected. The predictive performance of clinicopathologic variables and TSP-9 was compared, and TSP-9 was evaluated in clinically relevant patient subsets.

Results:
The sensitivity of the TSP-9 test in detecting progressors was 62.3% compared to 28.3% for expert-confirmed LGD, while the original diagnosis abstracted from medical records did not provide any significant risk stratification. The TSP-9 test identified 57% of progressors with NDBE (P<0.0001). NDBE patients who scored TSP-9 high risk progressed at a similar rate (3.2%/year) to patients with expert-confirmed LGD (3.7%/year). The TSP-9 test provided significant risk stratification in clinically low-risk patients (NDBE, female, short-segment) and clinically high-risk patients (IND/LGD, male, long-segment) (p<0.0001 for comparison of high- vs. low-risk classes).

Conclusions:
The TSP-9 test predicts risk of progression to HGD/EAC independently of current clinicopathologic variables in BE patients. The test provides objective risk stratification results that may guide management decisions to improve health outcomes for BE patients.
Investigating Themes That Are Embedded in Dagaaba Proverbs
Authors: Kogri Eugene Naah , Aduko Patrick Atanga 
Published: August 2023

A plethora of literature exist about proverbs in general and Dagaaba proverbs in particular but, little is said about the themes that are embedded in them with particular reference to the central dialect of Dagaare. It is very important to note that, the central dialect or otherwise the standard dialect of Dagaare is used for academic and examination purposes. This paper therefore seeks to investigate the concept and functions of proverbs and critically examine the themes that are embedded in Dagaaba proverbs. The functions of proverbs are put into two; didactic and aesthetic. The themes have been clearly explained in the work. A purposive sampling technique was implemented and the design of the research was qualitative. The research framework was content analysis since the data analysis was mainly descriptive. The sample population for the study was focused on three (3) language communities in Ulkpong Traditional area of the Upper West Region of Ghana. The instruments used for data collection were unstructured interview and participatory observation. Eight themes were identified in the proverbs. The theme of patience and perseverance, appreciation, unity, laziness, indiscipline, ignorance, hard work and greed were chosen because of their importance to human and national development. Proverbs are general seen as a cultural heritage, which is held in high regard since it is generally believed that the philosophy, value system, wisdom and knowledge of the society are embedded in them. The findings confirmed that Dagaaba proverbs have various themes as far as their contextual usage is concerned.
Auto-Tables: Synthesizing Multi-Step Transformations to Relationalize Tables without Using Examples
Authors: Li Peng , He Yeye , Yan Cong , Wang Yue , Chaudhuri Surajit 
Published: August 2023

Relational tables, where each row corresponds to an entity and each column corresponds to an attribute, have been the standard for tables in relational databases. However, such a standard cannot be taken for granted when dealing with tables "in the wild". Our survey of real spreadsheet-tables and web-tables shows that over 30% of such tables do not conform to the relational standard, for which complex table-restructuring transformations are needed before these tables can be queried easily using SQL-based tools. Unfortunately, the required transformations are non-trivial to program, which has become a substantial pain point for technical and non-technical users alike, as evidenced by large numbers of forum questions in places like StackOverflow and Excel/Tableau forums.
We develop an Auto-Tables system that can automatically synthesize pipelines with multi-step transformations (in Python or other languages), to transform non-relational tables into standard relational forms for downstream analytics, obviating the need for users to manually program transformations. We compile an extensive benchmark for this new task, by collecting 244 real test cases from user spreadsheets and online forums. Our evaluation suggests that Auto-Tables can successfully synthesize transformations for over 70% of test cases at interactive speeds, without requiring any input from users, making this an effective tool for both technical and non-technical users to prepare data for analytics.
Fetoscopic endoluminal tracheal occlusion (FETO) and bilateral congenital diaphragmatic hernia
Authors: Khawash Adrita , Kronfli Rania , Arasu Anusha , Gandhi Rashmi , Nicolaides Kypros , Greenough Anne 
Published: August 2023

Abstract

Objectives
Bilateral congenital diaphragmatic hernias (CDH) occur in one to two percent of CDH patients. There is a lower survival due to the greater likelihood of lung hypoplasia and associated anomalies. We report an infant with bilateral CDH and duodenal atresia who was successfully treated by fetoscopic endoluminal tracheal occlusion (FETO).

Case presentation
The fetus was diagnosed with CDH at 23 weeks of gestation. Her mother was referred to our tertiary centre as the observed to expected lung-to-head ratio (O/E LHR) at 26 weeks of gestation was only 17 %. The fetus was treated by FETO with an increase in the LHR. The mother had polyhydramnios and underwent amniotic fluid drainage at 26 and 31 weeks of gestation. She had preterm, premature rupture of the membranes at 31+3 weeks of gestation. The FETO balloon was punctured and the mother received corticosteroids. She underwent spontaneous labour at 35+6 weeks of gestation when the LHR was 55 %. At birth, the female infant was electively intubated and ventilated. After successful stabilisation, surgical intervention was undertaken on day six when the defects were identified as bilateral, type C posterolateral CDHs. Bilateral patch repair of the CDHs was undertaken using ‘domed’ Goretex patches. Type one duodenal atresia (DA) was identified and repaired with enterotomy and diamond duodenoduodenostomy. There was partial and then full abdominal closure on days 12 and 15 respectively. The infant is now four months of age and requires no respiratory support.

Conclusions
FETO can improve prognosis in infants with bilateral CDH.
16th ECFR-Symposium Discussion Report: Panel on Supply Chain Due Diligence
Authors: Knaier Ralf 
Published: August 2023

Abstract

240The last part of the afternoon session of the 16th annual ECFR Symposium in Leuven focused on a Panel on Supply Chain Due Diligence with Pierre-Henri Conac, Eva-Maria Kieninger and Harm-Jan de Kluiver. The discussion initially took place among the panel members themselves. Subsequently, further comments and questions were contributed by the audience.
Strigolactones promote plant freezing tolerance by releasing the WRKY41‐mediated inhibition of CBF/DREB1 expression
Authors: Wang Xi , Li Zhuoyang , Shi Yiting , Liu Ziyan , Zhang Xiaoyan , Gong Zhizhong , Yang Shuhua 
Published: August 2023

AbstractCold stress is a major abiotic stress that adversely affects plant growth and crop productivity. The C‐REPEAT BINDING FACTOR/DRE BINDING FACTOR 1 (CBF/DREB1) transcriptional regulatory cascade plays a key role in regulating cold acclimation and freezing tolerance in Arabidopsis (Arabidopsis thaliana). Here, we show that max (more axillary growth) mutants deficient in strigolactone biosynthesis and signaling display hypersensitivity to freezing stress. Exogenous application of GR245DS, a strigolactone analog, enhances freezing tolerance in wild‐type plants and strigolactone‐deficient mutants and promotes the cold‐induced expression of CBF genes. Biochemical analysis showed that the transcription factor WRKY41 serves as a substrate for the F‐box E3 ligase MAX2. WRKY41 directly binds to the W‐box in the promoters of CBF genes and represses their expression, negatively regulating cold acclimation and freezing tolerance. MAX2 ubiquitinates WRKY41, thus marking it for cold‐induced degradation and thereby alleviating the repression of CBF expression. In addition, SL‐mediated degradation of SMXLs also contributes to enhanced plant freezing tolerance by promoting anthocyanin biosynthesis. Taken together, our study reveals the molecular mechanism underlying strigolactones promote the cold stress response in Arabidopsis.
Mefloquine targets NLRP3 to reduce lipopolysaccharide‐induced systemic inflammation and neural injury
Authors: Jiang Si‐Yuan , Tian Tian , Li Wen‐Jie , Liu Ting , Wang Cong , Hu Gang , Du Ren‐Hong , Liu Yang , Lu Ming 
Published: August 2023

AbstractThe NLR family pyrin domain containing 3 (NLRP3) inflammasome plays an important role in the pathogenesis of a wide variety of human diseases. So far, drugs directly and specifically targeting the NLRP3 inflammasome are not available for clinical use since the safety and efficacy of new compounds are often unclear. A promising approach is thus to identify NLRP3 inhibitors from existing drugs that are already in clinical use. Here, we show that mefloquine, a well‐known antimalarial drug, is a highly selective and potent NLRP3 inhibitor by screening a FDA‐approved drug library. Mechanistically, mefloquine directly binds to the NLRP3 NACHT and LRR domains to prevent NLRP3 inflammasome activation. More importantly, mefloquine treatment attenuates the symptoms of lipopolysaccharide‐induced systemic inflammation and Parkinson's disease‐like neural damage in mice. Our findings identify mefloquine as a potential therapeutic agent for NLRP3‐driven diseases and migth expand its clinical use considerably.
Experimental Investigation and Analysis on Composite Brake Lining for Heavy Loading Crane
Authors: Ashish R. Pawar, Vikaskumar K. Mehtre Ganesh E. Kondhalkar, Mahesh P. Kumbhare, 
Published: August 2023

An ideal brake lining, which provides uniform and stable friction under all the operating conditions without any fade. The significance of friction material in material handling and earth moving machinery, commonly used friction material earlier contained asbestos as the base material mainly because of its property to resist deformation under action of heat generated due to friction. This review focuses on analysis of the brake friction lining material and other materials for band brake application. The measurement of friction force and the calculation of the coefficient of friction, coefficient of friction COF are critical for many industrial applications, e.g. Brakes, valves, clutches, similarly power and motion control mechanisms. High friction during machine operation not only generates heating that might cause failure of a machine part, but also consume a large amount of energy. It is estimated that one-third to one-half of the world’s energy production is wasted through friction.
Cochlear implant: factors that impact hearing outcomes
Authors: Casanova Maria J. , Castro Afonso , Lino João V. , Bernardes Cátia , Magalhães António , Meireles Luís 
Published: August 2023

Background: Cochlear implant has been providing hearing rehabilitation to patients with severe hearing loss. However, not all patients achieve optimal results, and the goal of this study was to evaluate the factors that influence hearing outcomes in cochlear implantation.
Methods: This was a retrospective analysis of the patients who underwent cochlear implantation in our institution between 2018 and 2021. Review of clinical files and complementary tests, and analysis of hearing outcomes and complications were performed.
Results: Sixty-nine cochlear implants were placed in 64 patients, with an average age of 49.3 years. In initial evaluation post activation and 1 year after implantation, the average pure tone average (PTA) was 37 dB, with a vocal discrimination of 48.7% at 50 dB, and 28, 6 dB, with a discrimination of 73.8% at 50 dB, respectively. Patients with postlingual deafness had better hearing outcomes at 1 year post surgery, in both PTA (27.9 compared to 33 dB) and discrimination at 50 dB (76.5 compared to 56.1%). Only one case had a major complication.
Conclusions: In conclusion, we found that increased implant use by the patient, postlingual deafness, and in-creased surgeon experience, were factors that improved hearing outcomes in patients undergoing cochlear implantation.
La traduction en français d’un message audiovisuel, le sous- titrage et la médiation interculturelle autour de la Fête de la moisson en Pologne – aspects théoriques et pratiques
Authors: Krupa Renata 
Published: August 2023

L’article aborde la problématique liée à la traduction d’un message audiovisuel polonais en français dans une classe de langue à l’université. L’objet du travail est de sensibiliser les étudiants aux aspects complexes de la traduction, compte tenu de la spécificité de la traduction audiovisuelle, plus précisément du sous-titrage, ainsi que de son adaptation technique à l’écran. Cet exercice a permis d’améliorer les compétences des apprenants en matière de techniques de traduction, de transfert culturel ainsi qu’en communication et médiation interculturelles.
Nous pouvons dire que la traduction audiovisuelle est une sorte de manipulation du texte source dont les contraintes techniques de présentation sont à prendre en compte.
Le thème du pain dans les albums de jeunesse documentaires : termes, contextes et défis pour la traduction
Authors: Grycan Magdalena 
Published: August 2023

Le thème du pain dans des albums documentaires pour la jeunesse choisis : termes, contextes et défis pour la traduction
Notre article a pour but de présenter le thème du pain tel qu’il est abordé dans des albums documentaires pour la jeunesse choisis. La présentation du lexique sur la fabrication du pain et sur la culture des céréales qui y est utilisé est complétée par l’analyse critique de la traduction polonaise de l’un des albums choisis Wiem co jem ! Chlebek i bułeczki (Je sais ce que je mange : Le pain). L’objectif de cette étude est de montrer les difficultés de nature terminologique, stylistique, culturelle et idéologique de ce type de traduction ainsi que de présenter comment et avec quel résultat elles ont été affrontées.
Mots clés : le pain, livre documentaire, album de jeunesse, traduction de la littérature de jeunesse, CLTS (Children Literature Translation Studies), adaptation, domestication
« Pain azyme » – c’est-a-dire ? Comment comprendre la caracteristique essentielle du pain eucharistique
Authors: Słowikowska Anna , Wojciechowski Grzegorz 
Published: August 2023

Dans le Droit Canon de 1983, le législateur définit des exigences canoniques par rapport à la validité de la matière eucharistique. Dans le can. 924 § 2 on trouve une disposition concernant le pain, qui doit être purement constitué de blé et bien frais. Alors que dans l’Introduction générale du Missel romain ces exigences ont été complétées par une indication des caractéristiques du pain eucharistique selon lesquelles il devrait être sans levain (n° 320).
Le but de cet article est de montrer cette dernière caractéristique comme essentielle et symbolique mais pas absolument nécessaire dans le contexte de la validité de la matière eucharistique dans l’Église catholique, car dans la liturgie latine, pour célébrer l’Eucharistie on utilise justement du pain azyme (sans levain), tandis que dans certaines Églises catholiques de rite oriental, on célèbre la Divine Liturgie avec du pain au levain.
Des réponses au problème de recherche ainsi posé seront précédées d’une analyse linguistique dans laquelle l’origine de l’adjectif polonais przaśny (‘sans levain’) sera expliqué avec des références à la source grecque ἄζυμος d’où vient le mot latin azymus et son équivalent français azyme (‘sans levain’).
Ultrasound-Guided Lumbar Peri-Facet Joint Blocks: A Therapuetuic Approach to Chronic Lower Back and Referred Leg Pain Management
Authors: Inklebarger James , KZ Syed 
Published: August 2023

Intra-articular fluoroscopically-guided facet joint (FJ) blocks are performed with diagnostic-therapeutic aims, whereas the main focus of ultrasound guided peri-facet joint blocks (USG-PFJB) is pain relief. USG-PFJB will therefore typically utilize higher injection volumes to potentially offer injection spread to other pain-generating structures. This study explores the potential role of USG-PFJBs in the outpatient management of chronic low back pain with our without leg symptoms in patients with MRI-confirmed mild to severe lower lumbar FJ arthrosis. USG-PFJBs were performed on 19 patients, (4 male and 15 females, mean age 55) at the L4/5 and/or L5/S1 segments at paraspinal points of palpable focal pain. All procedures were performed by the same clinician. One patient was lost to follow up and telephone reviews at 2-6 months on the remaining 18 patients, noted that 59.73% experienced significant & sustained pain relief. In conclusion, lower lumbar segment USG-PFJBs appear to be effective treatment option in patients with mild to severe MRI-confirmed FJ degeneration and palpable paraspinal lower back pain and with or without lower limb pain.
Revision of the Genus <em>Sycanus</em> Amyot & Serville, 1843 (Heteroptera: Reduviidae: Harpactorinae) from China Based on DNA Barcoding and Morphological Evidence
Authors: Zhao Ping , Chen Suyi , Wang Jianyun , Chen Zhuo , Li Hu , Cai Wanzhi 
Published: August 2023

Due to the variation of the body coloration and the similarity of the related species, there are still some unresolved problems and debates in the taxonomic study of the genus Sycanus in China. We conducted the inter-specific phylogenetic analyses and the species delimitation for Sycanus in China based on DNA barcoding dataset of the mitochondrial cytochrome c oxidase subunit I gene of 81 samples and partial 28S rDNA sequences of 31 samples. The result showed that all the samples were divided into twelve species by integrating the results of DNA barcoding and morphological comparison. In the present paper, the genus Sycanus in China was reviewed systematically, all species were described or re-described, keyed, illustrated and photographed, among them, Sycanus taiwanensis Zhao &amp;amp; Cai sp. nov., Sycanus hsiaoi Li &amp;amp; Cai sp. nov. and Sycanus hainanensis Wang &amp;amp; Cai sp. nov. were described as new to science. The biological informations of Sycanus falleni Stål, 1863 and Sycanus croceus Hsiao, 1979 were briefly recorded.
ASESMEN KOMPETENSI MINIMUM (AKM) KELAS SEKOLAH DASAR SEBAGAI SARANA EVALUASI KEMAMPUAN LITERASI DAN NUMERASI SISWA
Authors: Chesa Nabilla , Binti Azizatun Nafi’ah  
Published: August 2023

Salah satu kebijakan pemerintah yang dikeluarkan oleh Kementerian Pendidikan dan Kebudayaan untuk meningkatkan mutu pendidikan di Indonesia adalah melalui kebijakan kurikulum merdeka belajar. Pada kebijakan ini berisi pokok penilaian yang meliputi literasi dan numerasi. Seperti yang diketahui pandemi membawa dampak yang signifikan terhadap kualitas pendidikan di Indonesia, oleh sebab itu dalam kebijakan ini pemerintah mengadakan Asesmen Kompetensi Minimum (AKM) Kelas yang merupakan alat yang dapat digunakan oleh guru dalam menganalisis hasil belajar setiap siswa disekolah dasar. Hal ini tentu penting untuk mengetahui kompetensi yang dimiliki siswa setelah melaksanakan pembelajaran jarak jauh. Penelitian ini menggunakan metode penelitian kuantitatif. Penelitian ini memiliki tujuan untuk menganalisis dan mengetahui hasil dari penerapan Asesmen Kompetensi Minimum (AKM) Kelas. Hasil dari penelitian ini diharapkan berdasarkan pelaksanaan program ini dapat mempermudah guru dalam mengevaluasi hasil belajar siswa dan dapat mempermudah guru untuk menyusun pembelajaran sesuai dengan kebutuhan siswa yang berdasarpada hasil assesmen.
PENGELOLAAN DANA BANTUAN OPERASIONAL SEKOLAH (BOS) DI SD NEGERI SENDANGHARJO NGASEM KABUPATEN BOJONEGORO
Authors: Susanti Putri , Nafi’ah Binti Azizatun 
Published: August 2023

Kebijakan pemerintah dalam upaya peningkatan Pendidikan di Indonesia adalah dengan kebijakan Bantuan Operasional Sekolah (BOS). Pengelolaan BOS sendiri merupakan tanggung jawab dari Kepala Sekolah, Bendahara Sekolah dan juga Komite Sekolah. Tujuan dari penelitian ini adalah untuk menganalisis pengelolaan dana Bantuan Operasional Sekolah (BOS) di SD Negeri Sendangharjo Ngasem Kabupaten Bojonegoro dari tahap perencanaan, pelaksanaan dan juga pelaporan. Metode penelitian yang digunakan penulis adalah jenis pendekatan deskriptif dengan pendekatan kualitatif, yaitu data yang diperoleh penulis merupakan dari pengumpulan data dan literatur lainnya. Mendeskripsikan keadaan SD Negeri Sendangharjo Ngasem Kabupaten Bojonegoro dalam mengelola dana Bantuan Operasional Sekolah (BOS). Jenis data yang digunakan adalah data primer dan sekunder. Data primer merupakan data yang diperoleh dari wawancara dengan bendahara sekolah. Data sekunder merupakan data yang sudah pernah dikumpulkan sebelumnya bisa melalui buku, artikel, jurnal dan lainnya. Hasil penelitian menunjukkan bahwa pengelolaan dana BOS di SD Negeri Sendangharjo Ngasem Kabupaten Bojonegoro sudah sesuai dengan arahan dari Dinas Pendidikan Kabupaten Bojonegoro.