bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationship between Vedic personality traits (Sattva, Rajas, and Tamas) with life satisfaction and perceived stress in healthy university students
Authors: Sharma Shubham , Bhargav Praerna Hemant , Singh Pooja , Bhargav Hemant , Varambally Shivarama 
Published: March 2023

Introduction:

Trigunas are three basic mental attributes of a personality according to Indian Vedic literature that explains the relationship between mental attributes and human behavior. The three attributes are Tamas (tendency toward lethargy and rigidity), Rajas (tendency toward ambition and activity) and Sattva (tendency toward selfless service), respectively. Satisfaction with life and perceived stress are the important determinants of one's quality of life.

Aim:
A cross-sectional study assessed the relationship between Trigunas, life satisfaction and perceived stress.

Materials and methods:
The study recruited 121 willing healthy university students (75 females) with general health questionnaire scores ≤3. All participants were assessed using standardized psychometric tools.

Results:
Spearman two-tailed correlation test revealed Sattva to have positive correlation with life satisfaction (r = 0.503) and negative correlation with perceived stress (r = −0.302) and other two Gunas (Tamas: R = −0.77; Rajas: R = −0.75), respectively. On the other hand, both Rajas and Tamas correlated positively with perceived stress (Rajas: R = 0.183; Tamas: R = 0.321) and negatively with life satisfaction (Rajas: R = −0.40; Tamas: R = −0.36).

Conclusion:
This cross-sectional study on university students in India suggests an association of Vedic personality traits (Sattva, Rajas and Tamas Gunas) with life satisfaction, and perceived stress.
Early Experience Managing Complex Deformities Using Autostrut™ Robotic-Controlled Hexapod External Fixators
Authors: Hoellwarth Jason Shih , Rozbruch S. Robert , Reif Taylor J. , Geffner Adam Daniel , Fragomen Austin T. 
Published: March 2023

Context:
Hexapod circular external fixators allow bone manipulation in all planes to correct complex deformities. However, the patient must perform the strut adjustments consistently and correctly, often multiple times daily for weeks or months, to achieve intended corrections. This presents a potential source of variability, error, and anxiety to the patient. A computer-programmed, robotic automated motorized strut adjustment technology (Maxframe Autostrut™ Multi-Axial Correction System, Orthospin Ltd., Yoqneam, Israel) has been developed which automatically adjusts the struts without patient or clinician involvement.

Aims:
The aims of this study were as follows: first, to determine whether the motors performed the programmed initial and residual schedules and, second, to identify technology-specific problems and their management.

Settings and Design:
This was a retrospective observational study of a consecutive series of the first 16 patients who had the motorized hexapod frame applied.

Subjects and Methods:
A chart review was performed to record demographic information, indications and goals for hexapod frame care, whether the care goals were achieved, and whether unexpected and/or adverse events occurred (such as technical difficulties and medical complications) and the management of those issues.

Statistical Analysis Used:
Not applicable.

Results:
All patients achieved the index and residual adjustments as programmed.

Conclusions:
The Autostrut™ system appears reliable and safe. It executes programmed index and residual adjustments as well as strut change scenarios as directed. The system recognizes unexpected mechanical or programming issues and ensures patient safety by halting progress and alerting the patient. Future versions of the technology may benefit from added features such as remote reprogramming or current strut position monitoring.
Design and Fabrication of a Device for Reducing Hand Tremor in Parkinson Patients during Eating
Authors: Talaei Fereshteh , Kargar Seyed Mohammad 
Published: March 2023

Background:
In this paper, the method of designing a noninvasive device for eliminating hand tremors in Parkinson's patients is presented. The designed device measures the tremors of the patient's hand and implements the tremor control accordingly. Since Parkinson's disease reduces patients’ abilities to perform daily activities, this device is designed as an electronic spoon. The inertial measurement units are used to measure hand tremors.

Method:
The signals got from motion sensors are passed through Butterworth's second order low pass filters to attenuate signals amplitude at frequencies higher than the human hand's natural frequency. The signals are sent to a proposed Proportional Integral (PI) fuzzy controller as a set point signal, and appropriate control signals are applied to two actuators installed orthogonal. Besides motion sensors, a microcontroller is installed inside the spoon handle that implements a PI fuzzy controller and provides control signals for two high speed servo motors installed perpendicularly.

Results:
As such, the spoon can minimize the tremor effect. In this system, no damper or mass is added to the hand, and the patients are not required to wear an orthosis. The contribution of this paper is twofold. First, we use sensor data fusion to increase measurement accuracy. In this paper, we use accelerometer and gyroscope sensors. Second, we proposed a robust PI fuzzy controller to compensate for the uncertainties and reduce the tremor.

Conclusion:
The test results show that the hand tremor of Parkinson's patients during eating is reduced up to 75% using this method.
A Novel Texture Extraction-Based Compressive Sensing for Lung Cancer Classification
Authors: Irawati Indrarini Dyah , Hadiyoso Sugondo , Budiman Gelar , Fahmi Arfianto , Latip Rohaya 
Published: March 2023

Background:
Lung cancer images require large memory storage and transmission bandwidth for sending the data. Compressive sensing (CS), as a method with a statistical approach in signal sampling, provides different output patterns based on information sources. Thus, it can be considered that CS can be used for feature extraction of compressed information.

Methods:
In this study, we proposed a novel texture extraction-based CS for lung cancer classification. We classify three types of lung cancer, including adenocarcinoma (ACA), squamous cell carcinoma (SCC), and benign lung cancer (N). The classification is carried out based on texture extraction, which is processed in 2 stages, the first stage to detect N and the second to detect ACA and SCC.

Results:
The simulation results show that two-stage texture extraction can improve accuracy by an average of 84%. The proposed system is expected to be decision support in assisting clinical diagnosis. In terms of technical storage, this system can save memory resources.

Conclusions:
The proposed two-step texture extraction system combined with CS and K- Nearest Neighbor has succeeded in classifying lung cancer with high accuracy; the system can also save memory storage. It is necessary to examine the complexity of the proposed method so that it can be analyzed further.
A GU-Net-Based Architecture Predicting Ligand–Protein-Binding Atoms
Authors: Nazem Fatemeh , Ghasemi Fahimeh , Fassihi Afshin , Rasti Reza , Dehnavi Alireza Mehri 
Published: March 2023

Background:
The first step in developing new drugs is to find binding sites for a protein structure that can be used as a starting point to design new antagonists and inhibitors. The methods relying on convolutional neural network for the prediction of binding sites have attracted much attention. This study focuses on the use of optimized neural network for three-dimensional (3D) non-Euclidean data.

Methods:
A graph, which is made from 3D protein structure, is fed to the proposed GU-Net model based on graph convolutional operation. The features of each atom are considered as attributes of each node. The results of the proposed GU-Net are compared with a classifier based on random forest (RF). A new data exhibition is used as the input of RF classifier.

Results:
The performance of our model is also examined through extensive experiments on various datasets from other sources. GU-Net could predict the more number of pockets with accurate shape than RF.

Conclusions:
This study will enable future works on a better modeling of protein structures that will enhance knowledge of proteomics and offer deeper insight into drug design process.
Prediction of Biceps Muscle Electromyogram Signal Using a NARX Neural Network
Authors: Khodadadi Vahid , Rahatabad Fereidoun Nowshiravan , Sheikhani Ali , Dabanloo Nader Jafarnia 
Published: March 2023

Background:
This study was conducted to compare the response between the results of experimental data and the results achieved by the NARX neural network model to predict the electromyogram (EMG) signal on the biceps muscle in nonlinear stimulation conditions as a new stimulation model.

Methods:
This model is applied to design the controllers based on functional electrical stimulation (FES). To this end, the study was conducted in five stages, including skin preparation, placement of recording and stimulation electrodes, along with the position of the person to apply the stimulation signal and recording EMG, stimulation and recording of single-channel EMG signal, signal preprocessing, and training and validation of the NARX neural network. The electrical stimulation applied in this study is based on a chaotic equation derived from the Rossler equation and on the musculocutaneous nerve, and the response to this stimulation, i.e., the EMG signal, is from the biceps muscle as a single channel. The NARX neural network was trained, along with the stimulation signal and the response of each stimulation for 100 recorded signals from 10 individuals, and then validated and retested for trained data and new data after processing and synchronizing both signals.

Results:
The results indicate that the Rossler equation can create nonlinear and unpredictable conditions for the muscle, and we also can predict the EMG signal with the NARX neural network as a predictive model.

Conclusion:
The proposed model appears to be a good method to predict control models based on FES and to diagnose some diseases.
Echocardiographic Assessment of Left Ventricular Ejection Fraction Recovery after Primary Percutaneous Coronary Intervention in Patients Under 40 Years of Age
Authors: Balouch Iram Jehan , Khan Kamran Ahmad , Shaikh Sajid Ali , Rasheed Shazia , Khalid Muhammad Rahman , Ahmed Iftikhar , Sial Jawaid Akbar , Qamar Nadeem 
Published: March 2023

Context:
The context of this study was acute coronary syndrome.

Aims:
The purpose of the study was to evaluate left ventricular ejection fraction (LVEF) recovery in postprimary percutaneous coronary intervention (PPCI) patients under the age of 40 years.

Settings and Design:
Observational study, Hyderabad Satellite Center of National Institute of Cardiovascular Disease (NICVD), Pakistan.

Subjects and Methods:
This study was conducted on 104 patients at “NICVD, Hyderabad Satellite Center.” ST segment elevation myocardial infarction (STEMI) patients of both genders, between 18 and 40 years of age, and those who underwent coronary angiography were included in this study. LVEF of post-PPCI patients was assessed at admission, 40 and 90 days post-PPCI.

Statistical Analysis Used:
The McNemar–Bowker test was conducted to assess the variations in the distribution of LVEF at 40 and 90 days as compared to the baseline.

Results:
A total of 104 patients were included in this study. The mean age of the patients was 34.84 ± 4.82 years. The most common risk factors were hypertension 38.5% (40) and smoking 18.3% (19). At 6 weeks, 18.3% of patient's EF was 40%–50%. At 90 days, 23.1% EF was at 40%–50%. Maximum improvement in EF was seen in patients who timely underwent PPCI.

Conclusion:
A significant improvement in LVEF was observed in young STEMI patients after 40 and 90 days of PPCI. Timely intervention by PPCI not only preserves LV function at baseline but is also associated with better improvement in the short term in premature STEMI patients.
Acute pancreatitis due to hypertriglyceridemia
Authors: Sahin Gonca Koksaldi , Gulen Muge , Acehan Selen , Unlu Nurdan , Celik Yilmaz , Satar Deniz Aka , Segmen Mustafa Sencer , Satar Salim 
Published: March 2023

OBJECTIVE:
Hypertriglyceridemia (HTG) is the third-most common cause of acute pancreatitis. Plasmapheresis is an extracorporeal treatment method used for treatment. This study aimed to investigate the efficacy of medical treatment and plasmapheresis in patients with acute pancreatitis due to HTG.

METHODS:
This was a retrospective cross-sectional study. The patients were divided into two groups according to the treatment they received as those who received only medical treatment and those who performed plasmapheresis with medical treatment. According to the treatment received by the patients; clinical, demographic, and laboratory data, Ranson scores, and bedside index of severity in acute pancreatitis (BISAP) scores, decrease in triglyceride levels in 24 h, length of hospital stay, and outcomes were recorded.

RESULTS:
Forty-seven patients were included in the study. The level of triglyceride decreases at the 24th h was 59.7% ±17.3% in those who received medical treatment and was 70.4% ±15.1% in those who received plasmapheresis (P = 0.032). Receiver operating characteristic curve analysis was performed to predict the need for plasmapheresis treatment, area under the curve (AUC) value of the triglyceride level was the highest (AUC: 0.822, 95% confidence interval: [0.703–0.940]; P < 0.001), the sensitivity and specificity were 83.3% and 72.4%, respectively, and the cut-off value of triglyceride was accepted as 3079.5 mg/dL.

CONCLUSION:
Plasma triglyceride levels and BISAP score on admission may help physicians to predict the need for plasmapheresis. Plasmapheresis helps to rapidly reduce triglyceride levels in patients with HTG-associated acute pancreatitis.
An Analysis of Urban Household Earning Determinants: A Case Study of District Multan
Authors: Ahmad Rashid , Farooq Fatima , Rehman Saba , Faheem Muhammad 
Published: March 2023

The present study examined urban earning determinants in the district of Multan. For this purpose, primary cross-sectional data was collected from District Multan urban areas. Data was collected from district Multan through a structured questionnaire in which 385 respondents from urban areas were interviewed randomly. This study was analyzed through Elementary and Econometric analysis. The strict MEF was calculated by busing variables like education, experience and experience square. It was found that education and experience have a positive effect on earning while experience square negatively affected earning. Extended Mincerian Earning Function was calculating by using taking variables like education, experience, experience square, age, age square, spouse participation, migration, employment, and marital status. Education, experience, age, spouse participation, marital status, and migration positively effect on earnings while experience square, age square, and employment sector negatively affect earnings. The pairwise correlation analysis indicated a moderate problem of collinearity. Overall variables like (education, experience, age, migration, and spouse participation) have a higher impact on earnings in urban areas. The study suggests that the emphasis should be on improvement of education by investing in human capital as a result the quality of education, skill development, and the spread of knowledge can be improved which in turn can increases household earnings.
The Influence of Communication Participants on Adoption of Contagious Bovine Pleuropneumonia (CBPP) Vaccine among Arid and Semi-Arid Lands (ASAL) Pastoralists in Kenya
Authors: Ndungu Virginia Wangari , Mberia Hellen K , Wa Ngula Kyalo , Othieno Joseph 
Published: March 2023

Purpose: The purpose of this study was to establish the influence of communication participants on adoption of Contagious Bovine Pleuropneumonia (CBPP) Vaccine among Arid and Semi-Arid Lands (ASAL) pastoralists in Kenya.
Methodology: The study population was pastoralists in Narok South Sub-county. Sample size was 468 respondents inclusive of qualitative and quantitative samples where 440 responded to questionnaire, 24 in focus group discussions, and 4 in key informant interviews. Cross-sectional research design entailing collection of qualitative and quantitative data was used to assess association between variables. Multi stage, purposive, simple random, systematic and stratified sampling techniques were then employed to come up with respondents. Data derived from 468 respondents was analyzed using statistical Package for Social Scientists (SPSS) version 20.0 and presented using regression coefficients and ANOVA.
Findings: All respondents engaged in discussions with others before vaccinating cattle against CBPP. This is because as members of social groups, they interacted with each other through networks, a dominant mechanism for diffusion. Within parameters of experts, veterinary officers and agro-veterinary sales people were influential. In the community, family and neighbours were equally influential and among peers were elders and herders. These influencers were effective because of their attributes and social qualities; trustworthiness and credibility, accessibility, knowledgeability, government authority, advised on many issues, related easily with others and were friendly.
Unique contribution to theory, practice and policy: Some people have influence over others in CBPP vaccine adoption among ASAL pastoralists. Governments, veterinary researchers, and communication experts need to leverage on them to encourage diffuse of the vaccine. These influencers could also be trained on some basic aspects of disease reporting, control and eradication.
Single Stage Reconstructive Surgery to Treat Anorectal Malformations in Neonates; Ten Years Experience
Authors: Mumtaz Hussain Khan  , Naila Yaqub  
Published: March 2023

Objective: To present single surgeonâ€™s ten yearsâ€™ experience of Single stage reconstructive surgery in 26 neonates born with anorectal malformations (ARMs) and review of literature.
Methodology: This is a retrospective study of 26 neonates admitted in NICU with diagnosis of ARMs between period of June 2011 to Oct 2021 and managed by single stage reconstructive surgery with an average follow up of three years. All these patients were full term. The diagnosis was confirmed on clinical examination supported by cross table lateral film in prone position after 24 hours and ultrasound evaluation of level of rectal pouch. Single stage reconstructive surgery was done under general anesthesia within 24 to 48 hours after birth. The outcome of single stage reconstruction of neonates with anorectal malformations is evaluated post operatively during an average regular follow up of 3 years.
Results: All the 26 neonates are treated by single stage reconstructive surgery between 24 to 48 hours after birth during the period from June 2011 to Oct 2021 who were admitted with anorectal malformations in NICU after excluding associated congenital anomalies. Â All the patients had excellent cosmetic and functional outcome without significant problem of wound infection. Only 3 female patients with recto-vestibular fistula had mild superficial wound infection and were managed conservatively.
Conclusion: Single stage reconstructive surgery to treat ARMs in neonates I effective, safe and feasible with good continence. It avoids morbidity and higher cost associated with three stage surgeries and colostomy. This fact may further be confirmed through multi-institutional experience in large number of patients.
miR-10b-5p regulates venous endothelial cells in deep venous thrombosis by targeting MFG-E8
Authors: Li Ping , Liu Qingyun , Huang Zhenhua , Liu Yakun , Tang Feifei , Gao Sihai 
Published: March 2023

IntroductionDeep vein thrombosis (DVT) is a common venous thromboembolic disease with an unclear pathogenesis. miR-10b-5p expression was increased in DVT patients and this study aims to determine the functional mechanism of miR-10b-5p in DVT development.Material and methodsRats were injected with miR-10b-5p and MFG-E8 related plasmids before DVT model establishment. The thrombus length, weight and size were measured. TUNEL staining was used to detect apoptosis of vascular endothelial cells. Cell transfection on HUVECs was performed to achieve miR-10b-5p suppression or/and MFG-E8 suppression. The cell viability, migration, angiogenesis ability and cell apoptosis of HUVECs were measured. The expression levels of miR-10b-5p, MFG-E8, JAK/STAT signal pathway related proteins in peripheral blood of DVT patients, rats, and HUVECs were detected by RT-qPCR and Western blot.ResultsDVT patients increased expression of miR-10b-5p and decreased expression of MFG-E8. miR-10b-5p expression was negatively correlated with MFG-E8. Rats with inhibition of miR-10b-5p or overexpression of MFG-E8 had less deteriorated thrombus, decreased thrombus length and weight, cell apoptosis and suppressed ratio of p-JAK/JAK and p-STAT3/STAT3. miR-10b-5p can negatively regulate and target MFG-E8 in HUVECs. HUVECs transfected with miR-10b-5p inhibitor had increased cell viability, migration and angiogenesis ability as well as suppressed cell apoptosis and decreased p-JAK/JAK and p-STAT3/STAT3 ratio, while co-transfection of miR-10b-5p inhibitor and MFG-E8 suppression can partially counteract the miR-10b-5p inhibitor.ConclusionsElevated expression of miR-10b-5p and decreased MFG-E8 expression were found in peripheral blood of DVT patient and inhibition on miR-10b-5p or overexpression of MFG-E8 can attenuate DVT in rat models.
5E-led hospital-community-family care in patients with lung cancer surgery: it does work
Authors: Jiang Lingyan , Sun Fengqiu , Li Juan , Tang Yingying , Zhu Lingling , Gu Ju 
Published: March 2023

IntroductionPostoperative pulmonary rehabilitation is a very important part in the treatment and nursing care of patients with lung cancer. We aimed to evaluate the effects of 5E (encouragement, education, exercise, employment and evaluation)-led hospital-community-family care model in patients with lung cancer.Material and methodsPatients with lung cancer undergoing surgery treatment in our hospital from January 1, 2021 to February 15, 2022 were selected. The patients were randomly assigned to the control and 5E group. The cardio-pulmonary function, quality of life and psychosocial adjustment level were evaluated and compared.ResultsA total of 154 patients with lung cancer involving 78 patients in the control group and 76 patients in the 5E groups were included. There were significant differences in the forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC) at the one month, three months and six months follow-up between two group (all p<0.05). There were significant differences in the FEV1/FVC and peak expiratory flow (PEF) at six months follow-up between control group and 5E group (all p<0.05). There were significant differences in the 6 min walking test (6MWT), World Health Organization Quality of Life-100 Scale (WHOQOL-100) score and Self-report Psycho-social Adjustment to Illness Scale (PAIS-SR) score at the one month, three months and six months follow-up between two groups (all p<0.05).Conclusions5E-led hospital-community-family care model is beneficial to improve the cardiopulmonary function and quality of life in patients with lung cancer, which may worth promoting and using in clinical care of patients with lung cancer.