bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of the database of the collections of the Geological museum named after A. A. Chernov
Authors: Popvasev K. 
Published: June 2023

In modern museums, information and analytical systems complete many tasks related to museum activities. The application of generally accepted software systems, developed for subordinate museums of the Ministry of Culture of the Russian Federation, is limited in natural science museums. Often, natural science museums develop their own databases and information systems.
This article describes the development of a database of collections of the Geological Museum named after A. A. Chernov. We present main results of study — the design of a datalogical model.
The problem of loneliness in the urban environment: experience of cities in Russian Far East
Authors: Panfilova Anna 
Published: June 2023

The article deals with the phenomenon of human loneliness in the city. The ever-increasing role of the city as a living space causes changes both in the way of life of a person and in his inner world. Loneliness, being at all times an immanent companion of being, is also distinguished by specific features in modern social realities. Their formation was influenced by dynamic social factors and agents. The purpose of the article is to outline the social contour of urban loneliness by analysing relevant theoretical, methodological and empirical data.
The methodology for researching the issue was determined by the urban discourse in sociology (G.Simmel, R.Park, A.Lefebvre); social concepts of loneliness (N.Pokrovsky, Zh.Puzanova, E.Klinenberg); the concept of a modern complex society (Z.Bauman, S.Kravchenko), as well as elements of the socio-spatial approach. The empirical basis of the research is represented by a series of semi-formalised focused interviews with respondents - residents of large cities of the Far Eastern Federal District of the Russian Federation using the narrative principle of data processing, as well as elements of content analysis.
The results of the study are presented by empirically identified narratives of loneliness, the interpretation of their social context. The grounds for the analysis of loneliness as a phenomenon receiving additional development in the conditions of multidirectional and non-linear processes of urban life are noted. A factor social role in this process is played by the diversity and differentiation of public life, social anomie and individualisation of life practices, the crisis of the institution of trust as a value of collective interactions, and the ongoing “atomisation” of households. Also of major importance are the fundamental shifts in the mass consciousness, that led to the perception of a voluntary solitary lifestyle as beneficial and valuable. The social contours of loneliness are affiliated with the intensity of the urban lifestyle, individualism, and uncertainty about the future.
The author formulates a conclusion about the low level of social capital of respondents as one of the significant factors of loneliness, as well as about the resource nature of the city in the development of loneliness as a personal experience, and in the practice of a lonely lifestyle.
The phenomenon of network-centrism in conditions of modern cognitive opposition: on the example of the analysis of the Kherson case
Authors: Yarmak Olga , Bakulin Alexander , Bakulin Dmitry 
Published: June 2023

The presented article discusses a new social phenomenon of network-centrism and its manifestations in the conditions of modern cognitive confrontation on the example of the analysis of the Kherson information space. This research topic is currently of particular relevance due to the introduction of new tools of network warfare in the physical, informational, cognitive and social spheres of life of individuals through the functioning of information impact centкes in post-conflict societies.
Network-centrism in terms of cognitive confrontation is understood as a completely new social and civilisational phenomenon. Network-centric operations are understood by the authors as a kind of postmodern analogue of colonisation and subjugation, carried out in new conditions, in new formats and using new communication technologies. The main feature of the strategy of network wars using network-centric mechanisms is to achieve a damaging effect in all spheres of society, including its civilisational foundations. At the same time, not the power mechanisms of influence are used, but a wide range of factors - from civilisational and informational to social and cognitive ones.
The analysis of network-centric operations is carried out through the prism of the classical concepts of network societies, the theory of &amp;quot;controlled chaos&amp;quot;, as well as taking into account applied domestic ones - the doctrine of he USSR Marshal N.V. Ogarkov and foreign developments - the concept of network-centric wars by Vice Admiral of the US Navy A. Cebrowski, Pentagon researcher J. Garstka and Admiral J. Johnson.
The idea of the study was to analyse the network structures of the content units of the information field of the Kherson region, that form military, crisis and post-crisis discourses.
The results obtained by the authors indicate the presence of two information impact centres that use network-centric mechanisms of work in the cognitive field. In addition, the analysis of the work of network information centres showed that today the social media segment, primarily the Telegram segment, is a space for active network-centric influence on the mass consciousness of a conflict society, that creates an experimental platform for testing new tools of cognitive confrontation and forms an Internet audience, that is exposed to direct information impact and manifestations of network centrism in society.
Research of mutual perception of the Republic of Korea and Russia in the period 2016-2021
Authors: Choi Wooik 
Published: June 2023

The study of the mutual perception of Korea and Russia can be considered an important form of cultural exchange for understanding the perception of the people and culture of another country. In addition, this project explores obstacles to the development of bilateral relations and possible points of contact for cooperation, that helps to determine the direction for strengthening the strategic partnership. This article is based on the results of the 2021 study, with particular attention to the differences in perceptions of the peoples of both countries and its changes since 2016.
Koreans still associate Russia with images of the past - the Soviet Union, a communist country, and communism. Russians associate South Korea with modern concepts such as the development of industry and technology and Korean culture. Both peoples express a desire to visit another country, while the interest in culture is slightly higher among Russians.
There are no significant changes in the perception of Koreans in bilateral relations. The proportion of Korean respondents expressing a positive attitude towards political cooperation has slightly decreased, positive sentiments can also be observed in relation to cooperation in the economic sphere. There are also no significant changes in Russians' perception of relations between the two countries. The proportion of those who positively assess the prospects for current bilateral relations has slightly decreased, just like the Koreans, the Russians have a positive attitude towards economic cooperation.
As the analysis of the survey results showed, cooperation between South Korea and the United States as allies and confrontation between Russia and the United States is the main obstacle to the development of relations between Russia and Korea. Foreign policy problems remain a decisive factor in the development of cooperation. Thus, in public opinion, a practical and effective way to develop bilateral relations can be an exchange in the field of economy, medicine, tourism and culture at the level of the private sector and local authorities, rather than political and diplomatic cooperation at the state level.
Structural and functional state of postinfarction myocardium and vascular endothelial growth factor: is there a connection?
Authors: Vorob'ev A. M. , Ruzov V. I. , Salmin A. S. , Mel'nikova M. A. 
Published: June 2023

Purpose of the study. To reveal the relationship between the serum concentration of vascular endothelial growth factor and the structural and functional state of the myocardium in patients in the post-infarction period at the stage of rehabilitation.Materials and methods. We examined 94 patients at the outpatient stage of rehabilitation after ad hoc stenting 6 weeks after myocardial infarction, 10 healthy volunteers without somatic pathology. All participants in the study underwent standard transthoracic echocardiography with assessment of thickness of epicardial fat, assessment of the concentration of vascular endothelial growth factor (VEGF) in peripheral blood by ELISA.Results and discussion. VEGF values above the median values were associated with lower left ventricular ejection fraction and left ventricular fraction shortening, which indirectly may indicate a more pronounced expression of VEGF in patients with left ventricular systolic dysfunction. Assessing the parameters of LV diastolic dysfunction in groups with different levels of VEGF, no significant differences were found in patients after myocardial infarction. Correlation relationships between the content of VEGF and the thickness of epicardial adipose tissue were not found either among patients or in the control group.Conclusions. Elevated VEGF values in patients with coronary artery disease at the 6th week of rehabilitation were accompanied by left ventricle systolic dysfunction, in contrast to diastolic dysfunction. There was no direct correlation between the thickness of epicardial fat and the concentration of VEGF in the blood serum in patients with coronary artery disease.
Characteristics of the manifestations of the epidemic process of actual natural focal infections in the Samara region
Authors: Chupakhina L. V. , Vandysheva T. V. , Bilev A. E. , Bileva N. A. 
Published: June 2023

Features of the landscape and geographical conditions of the Samara region, the rich world of flora and fauna create favorable conditions for the existence of natural foci of infectious and parasitic diseases. The high population density, the presence of megacities (Samara, Togliatti), the passion of the inhabitants of the region for country recreation, together with developed agriculture, determine a high risk of infection of people with pathogens of natural focal infections.Objectives: to analyze the manifestations of the epidemic and epizootic processes of natural focal infections in the Samara region for its zoning according to the degree of danger of infection of the population with actual zoonoses.Methods. We used information on the incidence of the population (form No. 2 "Information on infectious and parasitic diseases") for the period from 2019 to 2021, data from an immunological examination of residents of municipalities using enzyme immunoassay, results of examination of environmental objects in natural foci (indication of genomes and antigens of viruses and bacteria) in vertebrates and their pellets (litter), arthropods using polymerase chain reaction and enzyme immunoassay. Cluster analysis was performed using the Statgraphics plus for Windows application program for a personal computer.Results. Territories with high, moderate and low risk of infection of the population of the Samara region with hemorrhagic fever with renal syndrome, viral tick-borne encephalitis, tularemia, leptospirosis, Q fever and West Nile fever were identified. It is shown that the most relevant zoonosis is hemorrhagic fever with renal syndrome.Discussion. Compiled cartographic mapping of the administrative formations of the Samara region with different risks of infection and disease of people with natural focal infections is relevant for planning preventive measures.
Development of a spectrophotometric method for assessment of the relative reactivity of monocarbonyl analogs of curcumin with 2-(dimethylamino)ethanethiol
Authors: Lozanovski Zlatko , Petreska Stanoeva Jasmina , Bogdanov Jane 
Published: June 2023

In order to improve the bioavailability of curcumin, studies have been undertaken to prepare the so-called monocarbonyl analogs of curcumin (MACs) and assess their biological activity. These analogs contain an electrophilic α,β-unsaturated carbonyl moiety (Michael acceptor). Several key biological processes are connected/controlled with thiol alkylation (glutathione, cysteine, cysteine peptide residues). The most likely reaction is the Michael addition between the α,β-unsaturated acceptor and a corresponding thiol. 2,6-Bisarylidenecyclohexanone and 3,5-bisarylidenepiperidin-4-one scaffolds offer convenient tunability of electrophilicity and redox properties of the Michael acceptor by the introduction of various substituents. In this study, several MACs were prepared by Claisen-Schmidt condensation reaction, and their reactivity with 2-(dimethylamino)ethanethiol was evaluated. For this purpose, based on the UV-Vis spectra of the analogs and thiol(s), a proper method for spectrophotometric evaluation of their reactivity with 2-(dimethylamino)ethanethiol was optimized. The relative reactivity of the analogs was 7 > 2 > 5 > 4 > 1 ≈ 6. The developed method is simple, and it can be extended to assess the reactivity of other MACs.
SЕNSORS BASED ON POLYCRYSTALLINE 3C-SiC: IMPACT OF BORON DOPING
Authors: Rodionov Volodymyr , Bratus Тatjana , Bubulis Algimantas 
Published: June 2023

As a chemically inert wide bandgap semiconductor material with high hardness and thermal conductivity, stable electrical characteristics, silicon carbide SiC is attractive for harsh environment electronics and sensors applications. The concept of harsh environment includes extremes of temperature, pressure, shock loads, radiation and chemical attacks those arise in aircraft and automotive engines, industrial gas turbines, during oil and gas exploration, etc.
Lower growing temperatures of polycrystalline cubic silicon carbide, pc-3C-SiC, compared to monocrystalline allow to significantly reduce its cost and expand the possibilities of application. It follows from previous works that the thermal sensitivity of pc -3C-SiC can be significantly increased by doping with an acceptor impurity of boron during the growth of the material. The purpose of this work is to determine the properties of pc-3C-SiC doped with boron for the creation of photosensors and thermosensors, as well as thermal anemometers for extreme operating conditions.
It is shown that pс-3C-SiC doping with a boron impurity in the growth process causes the formation of acceptor-type centers in the band gap and the appearance of features in the photosensitivity spectrum, which may be of practical interest for photovoltaics. For temperatures T > 150K, the conductivity of the doped sample increases almost exponentially with an activation energy of 0.28 eV, which is close to the activation energy of the photoconductivity of the same sample. This indicates that the ionization process of equilibrium and non-equilibrium charge carriers occurs from the same impurity centers. Boron doping causes the appearance of a broad photoconductivity band with a maximum at 1.7 eV in the impurity absorption region of pc-3C-SiC, similar to the situation in single crystal 3C-SiC.
It was determined that the temperature coefficient of resistance for boron-doped pc-3C-SiC is 3.0´10-2 K-1 at T=300K and 1.1´10-2 K-1 at T=700K, which is almost an order of magnitude higher than for thermocouples, as well as for metals from which anemometer threads are made. The discussion of the obtained results allows to associate the value of the activation energy E=0.28 eV with the level of shallow boron in pc-3C-SiC and to assume this center is a point defect containing a boron atom that replaces a silicon atom in the 3C-SiC lattice, i.e. BSi.
Photosensors that can be used as solar cells in the near-IR range of 0.6 - 1.8 μm, and as photocells in the visible range of 0.4 - 0.6 μm are proposed. The ability of pc-3C-SiC to work in extreme operating conditions, as well as the low cost of device manufacturing technology based on it, compared to other SiC polytypes, allow it to be considered a suitable material for creating temperature sensors, thermo-anemometers and photosensors, as well as detectors for monitoring nuclear facilities.
NEW THIOPHENE BASED MATERIALS FOR EMISSIVE LAYERS OF ORGANIC LIGHT-EMITTING DIODES
Authors: Dudin Vladyslav , Ivanova Vita , Gordiiko Nataliia , Ponomarenko Sergiy , Monastyrsky Gennady 
Published: June 2023

Optoelectronic display devices have gained an important role in the modern world. Digital displays based on organic light-emitting diodes are taking one of the leading places among other displays due to high contrast and high-quality color gamut. The relative novelty of the technology is the reason for the insufficient number of researched materials for use in layers of organic light-emitting diodes. This paper analyzes the properties of molecular structures based on thiophene heterocycles, as well as the feasibility of their use for displays on exclusively organic light-emitting diodes and in complex technologies, such quantum dots color converter.
Three thiophene structures of type T (thiophene), TB (thiophene-benzene), TPy (thiophene-pyrrole) were chosen for the study. Modeling and computing of characteristics of molecular structures was performed with the software for quantum chemical calculations Gaussian 09 due to the wide range of quantum chemical methods implemented in it, as well as high efficiency and convenient user interface.
With the help of the selected software, modeling of molecules, optimization by B3LYP methods, and the values of HOMO and LUMO energy levels were calculated. Emission and absorption spectra of T, TB and TPy type structures were obtained. Based on the obtained results, the possible application of structures in the emitting layers of organic LEDs was determined. T-type molecules can be used as a material for creating a self-emitting layer for organic light-emitting diodes in the visible wavelength range. Molecules of the TB-type are suitable for creating devices with radiation in the ultraviolet range. Molecules of the TPy-type have no prospects for use in direct OLED radiation, but their characteristics allow us to propose these structures as sources of exciting radiation for the creation of devices with light color conversion technologies.
Guest Editorial: Europe and North America’s Widening Transition Trajectory
Authors: Govindji Al-Karim 
Published: June 2023

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High energy prices and a greater focus on energy security will not slow the world’s long-term ambition for a low-carbon future. However, annual analysis by DNV believes unprecedented pressure is reinforcing a two-speed energy transition.
Despite the turbulence across energy markets and the crisis in Ukraine, the company’s latest Energy Transition Outlook states that the cost of solar and wind energy and rising carbon costs, hitting EUR 100 ($109) in Europe, will outweigh the present short‑term shocks to the energy system. For the first time, the forecast sees non‑fossil energy nudge slightly above 50% of the global energy mix by 2050, largely due to the growth and “greening” of electricity production.
While global intentions to abate carbon emissions and curtail global warming are aligned, lower‑income regions, where cost is the main driver of energy policy, are seeing a totally different trend.

Europe—The Leader of the Decarbonization Pack
Europe is the clear frontrunner as it looks to double down on renewables and energy efficiency to achieve net zero and strengthen its energy security to attain energy independence in the longer term.
Final energy demand will change profoundly in the next 3 decades and will decrease by 21%, influenced by energy‑efficiency gains and rapid electrification. For instance, due to the COVID‑19 pandemic and supply shock emanating from the invasion of Ukraine, gas consumption will fall dramatically in the short term to almost half the amount in 2050. Gas will meet just 10% of Europe’s energy demand in 2050 compared with 25% today (Fig. 1).
Fossil fuel use will be more confined to a few sectors representing only 28% of the primary energy mix by 2050. Oil demand will decrease from 19 exajoule (EJ) in 2020 to 8 EJ in 2050 and will mainly come from nonenergy use in the petrochemical industry (40%) and transport (37%). The strong decrease in demand will mean that total imports will decrease by 61% for oil and 64% for natural gas from 2020 to 2050.
Meanwhile, the share of renewable energy will rise from 40 to 45%. EU targets include:
- 320 GW of solar PV capacity by 2025 and almost 600 GW by 2030
- Half of electricity to come from wind by 2050. This will see onshore wind expand from 173 GW today to 1,000 GW. Offshore wind will rise fivefold from 60 GW wind by 2030 to 300 GW by mid‑century.
The REPowerEU strategy explicitly ties energy independence from Russia with increasing clean power and energy efficiency. With a host of initiatives aimed at ending the dependence on imported Russian fossil fuels by 2027, around EUR 210 billion ($229 billion) additional investment is needed over the next 4 years. The plan builds on the full implementation of the Fit for 55 proposals and suggests going further with higher renewable energy targets, including hydrogen and nuclear, and more meaningful energy efficiency efforts.
5-hydroxymethylcytosine features of portal venous blood predict metachronous liver metastases of colorectal cancer and reveal phosphodiesterase 4 as a therapeutic target
Authors: Lin Jian , Xu Nuo , Gao Zhaoya , Wu Deyan , Chen Hangyu , Zhang Zijian , Zhu Haichuan , Zhang Lei , Wang Yuchen , Lu Xuyang , Yao Xu , Liu Xuelan , Huang Yiyou , Wang Sen , Huang Dandan , Shi Jingyi , Huang Wensheng , Lei Fuming , Yang Zeruo , Chen Long , He Chuan , Luo Haibin , Gu Jin 
Published: June 2023

Abstract
Metachronous liver metastases (MLM) are characterized by high incidence and high mortality in clinical colorectal cancer treatment. Currently traditional clinical methods cannot effectively predict and prevent the occurrence of metachronous liver metastasis in colorectal cancer. Based on 5hmC-Seal analysis of blood and tissue samples, this study found that portal venous blood was more relevant to tumor gDNA than peripheral blood. We performed a novel epigenetic liquid biopsy strategy using the 10 5hmC epigenetic alterations, to accurately distinguish MLM patients from patients without metastases. Among these epigenetic alterations, phosphodiesterase 4 (PDE4D) was highly increased in MLM patients and correlated with poor survival. Moreover, our studies demonstrated that PDE4D was a key metastasis-driven target for drug development. Interfering with the function of PDE4D significantly repressed liver metastases. Similarly, roflumilast, a PDE4 inhibitor approved for Chronic obstructive pulmonary disease (COPD) also inhibits liver metastases. Roflumilast treatment significantly inhibited the protein levels of HIF-1α, CCN2, p-AKT and p-ERK, thus suppressing metastases. To develop a more efficient PDE4D inhibitor and reduce the occurrence of adverse events, we also designed several new compounds based on 2-arylbenzofurans and discovered lead L11 with potent affinity for PDE4D and significant suppression of liver metastases. Interestingly, we further found that compound L11 was better tolerated in terms of emetic activity on beagle dogs than roflumilast. Summarily, our study provides a promising strategy for predicting metachronous liver metastasis and discovers roflumilast as a potential repurposed drug for inhibiting liver metastasis, which have the potential to benefit patients with CRC in the future.