bluuebunny/crossref_metadata_2025_split huggingface dataset:
On solving the kinematics and controlling of origami box-shaped robot
Authors: Thai Phuong Thao , Nguyen Ngoc Hai 
Published: January 2023

<span lang="EN-US">Nowadays, there are various research on transformable robot. The use of origami pattern for transformable robot can be found in many research. The disadvantages of traditional origami model are the suitable material for folding is zero thickness, complicated patterns and overconstrained mechanism. In this paper, the idea of designing 1 degree-of-freedom box-shaped robot is proposed and two types of robot design have been analyzed. The first design is the waterbomb robot, that uses the traditional origami pattern. The second model takes the Sarrus linkage as the main mechanism for the mobile robot. In both designs, only one motor is required for the transformation of the robot, making the robot light-weight and portable. This paper analyzes the kinematic and dynamic properties of two transformable robots by using MATLAB. The comparison of the torque required for forming 3D shape has been done for optimizing robot design. Finally, the real model optimized design is introduced to illustrate the proposed method. </span>
Prediction Model Based on Easily Available Markers for Aberrant Cardiac Remodeling in Women After Pregnancy
Authors: Mohseni-Alsalhi Zenab , B.N.J. Janssen Emma , Delmarque Jil , van Kuijk Sander M.J. , Spaanderman Marc E.A. , Ghossein-Doha Chahinda 
Published: January 2023

BACKGROUND:
Preeclampsia is strongly associated with left ventricular concentric remodeling (LVCR) and left ventricular hypertrophy (LVH) up to 10 years after delivery. This predisposes to heart failure later in life. Adequate detection and prediction of LVCR or LVH is expected to decrease the risk of developing clinical heart failure within this high-risk female population. Therefore, we developed and internally validated a prediction model for aberrant cardiac remodeling in formerly pregnant women.

METHODS:
This large cohort study included women with a history of preeclampsia or normotensive pregnancy within a postpartum interval of 6 months to 30 years. Cardiovascular assessment was performed, including echocardiography, 30-minute blood pressure measurements, and circulating biomarkers. Aberrant cardiac remodeling based on echocardiographic findings was defined as either LVCR or LVH. Discriminative performance was evaluated by the area under the receiver operating characteristic curve.

RESULTS:
A total of 1397 women were included, of which 139 (10%) with LVCR or LVH (mean±SD age, 43±9 years) and 1258 (90%) without LVCR or LVH (40±8 years). The final prediction model was established based on the predictors age, waist circumference, systolic blood pressure, glycated hemoglobin, antihypertensive medication use, and early onset preeclampsia (yes/no). After internal validation, the prediction model showed accurate discriminative ability with an area under the receiver operating characteristic curve of 0.702 (95% CI, 0.657–0.756).

CONCLUSIONS:
Based on the conventional predictors, we developed a prediction model for women who are on average 8 to 12 years postpartum. Internal validation showed accurate discriminative ability. Upon external validation, this model may aid clinicians to initiate further diagnostic testing or clinical follow-up.

REGISTRATION:

URL:
https://www.clinicaltrials.gov
; Unique identifier: NCT02347540.
Long‐Term Visit‐to‐Visit Glycemic Variability as a Predictor of Major Adverse Limb and Cardiovascular Events in Patients With Diabetes
Authors: Hsu Jung‐Chi , Yang Yen‐Yun , Chuang Shu‐Lin , Huang Kuan‐Chih , Lee Jen‐Kuang , Lin Lian‐Yu 
Published: January 2023

Background
Peripheral arterial disease (PAD) is a severe complication in patients with type 2 diabetes. Glycemic variability (GV) is associated with increased risks of developing microvascular and macrovascular diseases. However, few studies have focused on the association between GV and PAD.

Methods and Results

This cohort study used a database maintained by the National Taiwan University Hospital, a tertiary medical center in Taiwan. For each individual, GV parameters were calculated, including fasting glucose coefficient of variability (FGCV) and hemoglobin A1c variability score (HVS). Multivariate Cox regression models were constructed to estimate the relationships between GV parameters and composite scores for major adverse limb events (MALEs) and major adverse cardiovascular events (MACEs). Between 2014 and 2019, a total of 45 436 adult patients with prevalent type 2 diabetes were enrolled for analysis, and GV was assessed during a median follow‐up of 64.4 months. The average number of visits and time periods were 13.38 and 157.87 days for the HVS group and 14.27 and 146.59 days for the FGCV group, respectively. The incidence rates for cardiac mortality, PAD, and critical limb ischemia (CLI) were 5.38, 20.11, and 2.41 per 1000 person‐years in the FGCV group and 5.35, 20.32, and 2.50 per 1000 person‐years in HVS group, respectively. In the Cox regression model with full adjustment, the highest FGCV quartile was associated with significantly increased risks of MALEs (hazard ratio [HR], 1.57 [95% CI, 1.40–1.76];
P
<0.001) and MACEs (HR, 1.40 [95% CI, 1.25–1.56];
P
<0.001). Similarly, the highest HVS quartile was associated with significantly increased risks of MALEs (HR, 1.44 [95% CI, 1.28–1.62];
P
<0.001) and MACEs (HR, 1.28 [95% CI, 1.14–1.43];
P
<0.001). The highest FGCV and HVS quartiles were both associated with the development of PAD and CLI (FGCV: PAD [HR, 1.57;
P
<0.001], CLI [HR, 2.19;
P
<0.001]; HVS: PAD [HR, 1.44;
P
<0.001], CLI [HR, 1.67;
P
=0.003]). The Kaplan‐Meier analysis showed significantly higher risks of MALEs and MACEs with increasing GV magnitude (log‐rank
P
<0.001).

Conclusions
Among individuals with diabetes, increased GV is independently associated with the development of MALEs, including PAD and CLI, and MACEs. The benefit of maintaining stable glycemic levels for improving clinical outcomes warrants further studies.
High Plasma Levels of Soluble Lectin‐like Oxidized Low‐Density Lipoprotein Receptor‐1 Are Associated With Inflammation and Cardiometabolic Risk Profiles in Pediatric Overweight and Obesity
Authors: Stinson Sara E. , Jonsson Anna E. , Andersen Mette K. , Lund Morten A. V. , Holm Louise Aas , Fonvig Cilius E. , Huang Yun , Stankevič Evelina , Juel Helene Bæk , Ängquist Lars , Sørensen Thorkild I. A. , Ongstad Emily L. , Gaddipati Ranjitha , Grimsby Joseph , Rhodes Christopher J. , Pedersen Oluf , Christiansen Michael , Holm Jens‐Christian , Hansen Torben 
Published: January 2023

Background
Lectin‐like oxidized low‐density lipoprotein (ox‐LDL) receptor‐1 is a scavenger receptor for oxidized low‐density lipoprotein. In adults, higher soluble lectin‐like ox‐LDL receptor‐1 (sLOX‐1) levels are associated with cardiovascular disease, type 2 diabetes, and obesity, but a similar link in pediatric overweight/obesity remains uncertain.

Methods and Results

Analyses were based on the cross‐sectional HOLBAEK Study, including 4‐ to 19‐year‐olds from an obesity clinic group with body mass index >90th percentile (n=1815) and from a population‐based group (n=2039). Fasting plasma levels of sLOX‐1 and inflammatory markers were quantified, cardiometabolic risk profiles were assessed, and linear and logistic regression analyses were performed. Pubertal/postpubertal children and adolescents from the obesity clinic group exhibited higher sLOX‐1 levels compared with the population (
P
<0.001). sLOX‐1 positively associated with proinflammatory cytokines, matrix metalloproteinases, body mass index SD score, waist SD score, body fat %, plasma alanine aminotransferase, serum high‐sensitivity C‐reactive protein, plasma low‐density lipoprotein cholesterol, triglycerides, systolic and diastolic blood pressure SD score, and inversely associated with plasma high‐density lipoprotein cholesterol (all
P
<0.05). sLOX‐1 positively associated with high alanine aminotransferase (odds ratio [OR], 1.16,
P
=4.1 E‐04), insulin resistance (OR, 1.16,
P
=8.6 E‐04), dyslipidemia (OR, 1.25,
P
=1.8 E‐07), and hypertension (OR, 1.12,
P
=0.02).

Conclusions
sLOX‐1 levels were elevated during and after puberty in children and adolescents with overweight/obesity compared with population‐based peers and associated with inflammatory markers and worsened cardiometabolic risk profiles. sLOX‐1 may serve as an early marker of cardiometabolic risk and inflammation in pediatric overweight/obesity.

Registration

The HOLBAEK Study, formerly known as The Danish Childhood Obesity Biobank,
ClinicalTrials.gov
identifier number NCT00928473,
https://clinicaltrials.gov/ct2/show/NCT00928473
(registered June 2009).
Prognostic Impact of Cardiac Diastolic Function and Coronary Microvascular Function on Cardiovascular Death
Authors: Hong David , Lee Seung Hun , Shin Doosup , Choi Ki Hong , Kim Hyun Kuk , Ha Sang Jin , Joh Hyun Sung , Park Taek Kyu , Yang Jeong Hoon , Song Young Bin , Hahn Joo‐Yong , Choi Seung‐Hyuk , Gwon Hyeon‐Cheol , Lee Joo Myung 
Published: January 2023

Background
Coronary microvascular dysfunction (CMD) has been considered as a possible cause of cardiac diastolic dysfunction. The current study evaluated the association between cardiac diastolic dysfunction and CMD, and their prognostic implications in patients without significant left ventricular systolic dysfunction and epicardial coronary stenosis.

Methods and Results

A total of 330 patients without left ventricular systolic dysfunction (ejection fraction ≥50%) and significant epicardial coronary stenosis (fractional flow reserve >0.80) were analyzed. Cardiac diastolic dysfunction was defined by echocardiographic parameters (early diastolic transmitral flow velocity/early diastolic mitral annular velocity, e' velocity, tricuspid regurgitation velocity, and left atrial volume index). Overt CMD was defined as coronary flow reserve <2.0 and index of microcirculatory resistance ≥25 U. The primary end point was cardiovascular death or admission for heart failure during 5 years of follow‐up. In patients without left ventricular systolic dysfunction and significant epicardial coronary stenosis, prevalence of cardiac diastolic dysfunction and overt CMD was 25.5% and 11.2%, respectively. Overt CMD was independently associated with cardiac diastolic dysfunction (adjusted odds ratio, 3.440 [95% CI, 1.599–7.401];
P
=0.002). Patients with cardiac diastolic dysfunction showed significantly higher risk of the primary outcome than those without (adjusted hazard ratio [HR], 2.996 [95% CI, 1.888–4.755];
P
<0.001). Patients with overt CMD also showed significantly higher risk of the primary outcome than those without (adjusted HR, 2.939 [95% CI, 1.642–5.261];
P
<0.001). Presence of overt CMD was associated with significantly increased risk of cardiovascular death among the patients with cardiac diastolic dysfunction (43.8% versus 14.5%;
P
=0.006) but not in patients without cardiac diastolic dysfunction (interaction
P
<0.001). Inclusion of overt CMD into the model with cardiac diastolic dysfunction significantly improved predictive ability for cardiovascular death or heart failure admission (conconrdance index, 0.719 versus 0.737;
P
for comparison=0.034).

Conclusions
There was significant association between the presence of cardiac diastolic dysfunction and overt CMD. Both cardiac diastolic dysfunction and overt CMD were associated with increased risk of cardiovascular death or admission for heart failure. Integration of overt CMD into cardiac diastolic dysfunction showed improvement of the risk stratification in patients without significant left ventricular systolic dysfunction and epicardial coronary stenosis.

Registration
DIAST‐CMD (Prognostic Impact of Cardiac Diastolic Function and Coronary Microvascular Function) registry; Unique identifier: NCT05058833.
Trends in Incidences and Survival Rates in Pediatric In‐Hospital Cardiopulmonary Resuscitation: A Korean Population‐Based Study
Authors: Choi Jaeyoung , Choi Ah Young , Park Esther , Moon Suhyeon , Son Meong Hi , Cho Joongbum 
Published: January 2023

Background
Although the outcome of cardiopulmonary resuscitation (CPR) is still unsatisfactory, there are few studies about temporal trends of in‐hospital CPR incidence and mortality. We aimed to evaluate nationwide trends of in‐hospital CPR incidence and its associated risk factors and mortality in pediatric patients using a database of the Korean National Health Insurance between 2012 and 2018.

Methods and Results

We excluded neonates and neonatal intensive care unit admissions. Incidence of in‐hospital pediatric CPR was 0.58 per 1000 admissions (3165 CPR/5 429 471 admissions), and the associated mortality was 50.4%. Change in CPR incidence according to year was not significant in an adjusted analysis (
P
=0.234). However, CPR mortality increased significantly by 6.6% every year in an adjusted analysis (
P
<0.001). Hospitals supporting pediatric critical care showed 37.7% lower odds of CPR incidence (
P
<0.001) and 27.5% lower odds of mortality compared with other hospitals in the adjusted analysis (
P
<0.001), and they did not show an increase in mortality (
P
for trend=0.882).

Conclusions
Temporal trends of in‐hospital CPR mortality worsened in Korea, and the trends differed according to subgroups. Study results highlight the need for ongoing evaluation of CPR trends and for further CPR outcome improvement among hospitalized children.
Impact of Achieving Blood Pressure Targets and High Time in Therapeutic Range on Clinical Outcomes in Patients With Atrial Fibrillation Adherent to the Atrial Fibrillation Better Care Pathway: A Report From the COOL‐AF Registry
Authors: Krittayaphong Rungroj , Winijkul Arjbordin , Methavigul Komsing , Lip Gregory Y. H. 
Published: January 2023

Background
We aimed to determine the effect of integrating Atrial Fibrillation Better Care pathway compliance in relation to achievement of systolic blood pressure (SBP) targets and good control of time in therapeutic range (TTR) on clinical outcomes in patients with atrial fibrillation.

Methods and Results
We prospectively enrolled patients with nonvalvular atrial fibrillation from 27 hospitals in Thailand. All clinical outcomes were recorded. Main outcomes were the composite of all‐cause death or ischemic stroke/systemic embolism (SSE), as well as secondary outcomes of all‐cause death, SSE, major bleeding, intracranial hemorrhage, and heart failure. An SBP of 120 to 140 mm Hg was considered good blood pressure control. Target TTR was a TTR ≥65%. A total of 3405 patients were studied (mean age 67.8 years, 41.8% female). Full ABC pathway compliance was evident in 42.7%. For blood pressure control, 41.9% had SBP within target, whereas 35.9% of those on warfarin had TTR within target. The incidence rates of all‐cause death/SSE, all‐cause death, SSE, major bleeding, intracranial hemorrhage, and heart failure were 5.29, 4.21, 1.51, 2.25, 0.78, and 2.84 per 100 person‐years respectively. Adjusted hazard ratios and 95% CI of Atrial Fibrillation Better Care pathway compliance for all‐cause death/SSE, all‐cause death, and heart failure were 0.76 (0.62–0.94), 0.79 (0.62–0.99), and 0.69 (0.51–0.94), respectively, compared with noncompliance. Patients with Atrial Fibrillation Better Care compliance and SBP within target had a better outcome or TTR within target had better outcomes.

Conclusions
In COOL‐AF (Cohort of Antithrombotic Use and Optimal International Normalized Ratio Level in Patients With Non‐Valvular Atrial Fibrillation in Thailand), a multicenter nationwide prospective cohort of patients with atrial fibrillation, achieving SBP within target and TTR ≥ 65% has added value to Atrial Fibrillation Better Care pathway compliance in the reduction of adverse clinical outcomes in patients with atrial fibrillation.
Redescription of the type species of the genus Cypretta (Ostracoda, Crustacea), with notes on the taxonomy of the genus
Authors: FERREIRA VITOR GÓIS , HIGUTI JANET , MARTENS KOEN 
Published: January 2023

With 53 formally described species, the genus Cypretta is one of the most common freshwater ostracod genera in the world. It has a mainly circumtropical distribution. The type species, Cypretta tenuicauda (Vávra, 1895), was described from Zanzibar (Africa) in a superficial way. Therefore, the morphology and identity of this species and of the genus remained problematic until today.
Here, we redescribe Cypretta tenuicauda from the original type material and discuss the morphology of the species and the diagnosis of the genus. The species is characterized by the presence of anterior marginal septa in both valves, the sub-triangular carapace shape in lateral view, the right valve overlapping the left valve, the generally wide carapace and the presence of a serrated posteroventral inner list in the right valve. In addition, both α and β setae on the mandibular palp are long and thin, claws Ga and Gp on the caudal ramus are elongated and seta-like, while the caudal ramus itself is equally slender. The caudal ramus attachment is reduced to a simple branch.
The present redescription of the type species will assist in creating order in what is now a taxonomically confused genus.
Wind and Turbulence Effects on Raindrop Fall Speed
Authors: Testik Firat Y. , Bolek Abdullah 
Published: January 2023

Abstract
Wind and turbulence effects on raindrop fall speeds were elucidated using field observations over a 2-yr time period. Motivations for this study include the recent observations of raindrop fall speed deviations from the terminal fall speed predictions (Vt) based upon laboratory studies and the utilizations of these predictions in various important meteorological and hydrological applications. Fall speed (Vf) and other characteristics of raindrops were observed using a high-speed optical disdrometer (HOD), and various rainfall and wind characteristics were observed using a 3D ultrasonic anemometer, a laser-type disdrometer, and rain gauges. A total of 26 951 raindrops were observed during 17 different rainfall events, and of these observed raindrops, 18.5% had a subterminal fall speed (i.e., 0.85Vt ≥ Vf) and 9.5% had a superterminal fall speed (i.e., 1.15Vt ≤ Vf). Our observations showed that distributions of sub- and superterminal raindrops in the raindrop size spectrum are distinct, and different physical processes are responsible for the occurrence of each. Vertical wind speed, wind shear, and turbulence were identified as the important factors, the latter two being the dominant ones, for the observed fall speed deviations. Turbulence and wind shear had competing effects on raindrop fall. Raindrops of different sizes showed different responses to turbulence, indicating multiscale interactions between raindrop fall and turbulence. With increasing turbulence levels, while the raindrops in the smaller end of the size spectrum showed fall speed enhancements, those in the larger end of the size spectrum showed fall speed reductions. The effect of wind shear was to enhance the raindrop fall speed toward a superterminal fall.
Optimal Design of a Surface Precipitation Network in Canada
Authors: Brunet Dominique , Milbrandt Jason A. 
Published: January 2023

Abstract
The surface precipitation network in Canada suffers from large data gaps due to the challenge of covering a large country with a low population density. A proof-of-concept for an optimal network design is proposed to more efficiently estimate precipitation in Canada with the design goal of minimizing the interpolation uncertainty. The network design is based on a statistical model of precipitation that accounts for intermittency and non-Gaussianity of precipitation. Our results indicate that the greatest needs for new stations are in British Columbia, where coastal and mountain climate leads to more uncertainty in precipitation amounts, while the Prairie Provinces (Alberta, Saskatchewan, and Manitoba) could gain efficiencies by reducing their network size. Despite the current low density of stations in the territories north of Canada, these drier and colder regions only have a moderate need for more stations, mostly in the mountainous regions of Yukon. However, from a spatially varying wind undercatch measurement error model, it is shown that these northern regions have greatest need for higher-accuracy measurements.

Significance Statement
The proposed methodology can guide in the optimal placement of precipitation gauges across a large country such as Canada, which will provide value for money in how rain and snow are monitored.
Bernardevansite, Al2(Se4+O3)3⋅6H2O, dimorphous with alfredopetrovite and the Al-analogue of mandarinoite, from the El Dragón mine, Potosí, Bolivia
Authors: Yang Hexiong , Gu Xiangping , Jenkins Robert A. , Gibbs Ronald B. , Downs Robert T. 
Published: January 2023

AbstractA new mineral species, bernardevansite (IMA2022-057), ideally Al2(Se4+O3)3⋅6H2O, has been discovered from the El Dragón mine, Potosí Department, Bolivia. It occurs as aggregates or spheres of radiating bladed crystals on a matrix consisting of Co-bearing krut'aite–penroseite. Associated minerals are Co-bearing krut'aite–penroseite, chalcomenite and ‘clinochalcomenite’. Bernardevansite is colourless in transmitted light, transparent with white streak and vitreous lustre. It is brittle and has a Mohs hardness of 2½–3. Cleavage is not observed. The measured and calculated densities are 2.93(5) and 2.997 g/cm3, respectively. Optically, bernardevansite is biaxial (+), with α = 1.642(5), β = 1.686(5) and γ = 1.74(1) (white light). An electron microprobe analysis yielded an empirical formula (based on 15 O apfu) (Al1.26Fe3+0.82)Σ2.08(Se0.98O3)3⋅6H2O, which can be simplified to (Al,Fe3+)2(SeO3)3⋅6H2O.Bernardevansite is the Al-analogue of mandarinoite, Fe3+2(SeO3)3⋅6H2O or dimorphous with P$\bar{6}$2c alfredopetrovite. It is monoclinic, with space group P21/c and unit-cell parameters a = 16.5016(5), b = 7.7703(2), c = 9.8524(3) Å, β = 98.258(3)°, V = 1250.21(6) Å3 and Z = 4. The crystal structure of bernardevansite consists of a corner-sharing framework of M3+O6 (M = Al and Fe) octahedra and Se4+O3 trigonal pyramids, leaving large voids occupied by the H2O groups. There are two unique M3+ positions: M1 is octahedrally coordinated by (4O + 2H2O) and M2 by (5O + H2O). The structure refinement indicates that Al preferentially occupies M1 (= 0.692Al + 0.308Fe) over M2 (= 0.516Al + 0.484Fe). The substitution of the majority of Fe in mandarinoite by Al results in a significant reduction in its unit-cell volume from 1313.4 Å3 to 1250.21(6) Å3 for bernardevansite. The discovery of bernardevansite begs the question whether the Fe3+ end-member, Fe3+2(SeO3)3⋅6H2O, has two polymorphs as well, one with P21/c symmetry, as for mandarinoite and the other P$\bar{6}$2c, as for alfredopetrovite.