bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integrated Management of Corn Marigold (Glebionis segetum) in Tef Field at Western and Southwestern Shewa Zones in Ethiopia
Authors: Hundessa Niguse , Dechassa Nagassa , Bedada Shashitu , Bekele Getachew , Duguma Mosisa 
Published: June 2023

Background: Corn marigold (Glebionis segetum (L.) Frourr.) is a serious weed species of agricultural crops in many parts of Ethiopia. However, there is a lack of information on its management in tef fields in the country. Therefore, the current work was designed with the objectives of evaluating integrated management of the weed and determining the most economical integrated weed management options in tef fields. Methods: The field experiments were conducted in naturally corn marigold infested fields of Cheliya and Woliso districts of West and Southwest Shewa Zones in Ethiopia, respectively, during 2020 to 2021 cropping seasons. Results: Different corn marigold management practices exhibited different responses to different parameters of the target weed and the test crop differently. Application of Pyroxsulam 45g L-1 at a rate of 0.40 l ha -1 supplemented with once-hand weeding and Halauxifen-methyl 100g kg-1 + Florasulam 100g kg-1 sprayed at a rate of 50 g ha -1 supplemented with once-hand weeding increased grain yield by about 70 and 50%, respectively, over the weedy check. The marginal revenue and benefit-cost ratio obtained from the marketing of goods for the application of Pyroxsulam 45g L-1 with one supplementary hand weeding of corn marigold increased by110 89%, respectively, as compared to the weedy check. Conclusions: The present study revealed the role of integrated management of corn marigold in improving tef production and productivity by combating the weed. Future research should be directed towards scaling up and popularizing these technologies among the growers.
Charging Station Location and Sizing for Electric Vehicles Under Congestion
Authors: Kınay Ömer Burak , Gzara Fatma , Alumur Sibel A. 
Published: June 2023

This paper studies the problem of determining the strategic location of charging stations and their capacity levels under stochastic electric vehicle flows and charging times taking into account the route choice response of users. The problem is modeled using bilevel optimization, where the network planner or leader minimizes the total infrastructure cost of locating and sizing charging stations while ensuring a probabilistic service requirement on the waiting time to charge. Electric vehicle users or followers, on the other hand, minimize route length and may be cooperative or noncooperative. Their choice of route in turn determines the charging demand and waiting times at the charging stations and hence, the need to account for their decisions by the leader. The bilevel problem reduces to a single-level mixed-integer model using the optimality conditions of the follower’s problem when the charging stations operate as M/M/c queues and the followers are cooperative. To solve the bilevel model, a decomposition-based solution methodology is developed that uses a new logic-based Benders algorithm for the location-only problem. Computational experiments are performed on benchmark and real-life highway networks, including a new eastern U.S. network. The impact of route choice response, service requirements, and deviation tolerance on the location and sizing decisions are analyzed. The analysis demonstrates that stringent service requirements increase the capacity levels at open charging stations rather than their number and that solutions allowing higher deviations are less costly. Moreover, the difference between solutions under cooperative and uncooperative route choices is more significant when the deviation tolerance is lower. History: This paper has been accepted for the Transportation Science Special Issue on 2021 TSL Workshop: Supply and Demand Interplay in Transport and Logistics. Funding: This research was supported by the Ontario Graduate Scholarship when Ö. B. Kınay was a PhD candidate at the University of Waterloo, and this support is acknowledged. Supplemental Material: The online appendix is available at https://doi.org/10.1287/trsc.2021.0494 .
Cord care practices and use of chlorhexidine gel among mothers in a hospital in southwest Nigeria
Authors: Olubiyi Simeon K , Anyebe Emmanuel E , Adeyinka Morohunkeji K , Ololade Ruth O , Gambari Yusuf A , Ojo Funmilayo E , Adeola Richard , Bello Cecilia B , Akingbade Oluwadamilare 
Published: June 2023

Background/Aims Using chlorhexidine gel for neonates during the first week of life is an important strategy for preventing sepsis and achieving optimal cord care. This study aimed to assess knowledge and practice of cord care and the use of chlorhexidine gel among mothers attending a hospital in southwest Nigeria. Methods A descriptive survey was carried out, using random sampling to select 184 mothers attending antenatal and postnatal clinics in Lagos State General Hospital, Shomolu, Lagos. Associations between variables were tested using Pearson's correlation at 0.05 significance. Results Almost two-thirds (64.1%) of participants understood that the soiled umbilical stump should not be cleaned with water and over half (52.7%) disagreed with the use of substances such as methylated spirit, toothpaste and hot water for cord care. In practice, 97.8% cleaned the baby's umbilical cord and 84.8% cleaned the umbilical stump with chlorhexidine gel. Almost a fifth (19%) of participants applied other substances such as alcohol (methylated spirit), herbal preparations or hot water to the umbilical cord. A statistically significant association was found between knowledge and practice of cord care (P<0.001). Conclusions This study suggests that the use of chlorhexidine gel in cord care among mothers has improved compared to previous studies. More studies are needed to confirm this finding. Some participants used unhealthy cord care practices, including herbal preparations and hot water, implying a need for further interventions to address misconceptions.
Innovative protocol of an exploratory study evaluating the acceptability of a humanoid robot at home of deaf children with cochlear implants
Authors: Stiti Sabrina , Caroux Loïc , Gaillard Pascal , Paubel Pierre-Vincent , Deguine Olivier 
Published: June 2023

The purpose of this paper is to introduce a research methodology for the assessment of the acceptability of a humanoid robot at home for children with cochlear implants (CI). The quality of audiology rehabilitation for cochlear implanted child administrated at the hospital with pluri-weekly sessions is a major prognostic factor in the outcome on communications abilities, but represents also a constraint for families related to the access to care that are more difficult. Further, home training with tools would balance the equitable distribution of care in the territory and promote the child’s progress. The humanoid robot should allow an ecological approach to this complementary training. Before developing this approach, it is necessary to study the acceptability of the humanoid robot at home, both by cochlear implanted child and their families. Ten families were chosen to have a humanoid robot at home, to explore their acceptability of the humanoid robot Pepper. The study lasts for 1 month per participants (i.e. cochlear implemented children and parent). Participants were invited to use the robot at home as much as they want. The humanoid robot Pepper was able to communicate and proposed activities not related to rehabilitation. Once a week during the study, data were collected from participants (questionnaires and robot’s logs) and the smooth running of the study was checked. Questionnaires are used to evaluate the acceptability of the robot by children and parents. User data from the robot’s logs are used to quantify the time and the actual use of the robot over the period of the study. Results of the experimentation will be reported, once all 10 participants have completed their passation. The robot is anticipated to be used and accepted by children with cochlear implants and their families.
Clinical trial registration: Clinical Trials ID: NCT04832373; https://clinicaltrials.gov/.
The impact of COVID-19 lockdown on nursing higher education at Chengdu University
Authors: Cai Peiling , Shi Ya , Cui Jianing , Wang Junren , Ren Juan , Hambly Brett D. , Bao Shisan , Xu Zhongqing 
Published: June 2023

Background
To combat/control the COVID-19 pandemic, a complete lockdown was implemented in China for almost 6 months during 2020.

Purpose
To determine the impact of a long-term lockdown on the academic performance of first-year nursing students via mandatory online learning, and to determine the benefits of online teaching.

Methods
The recruitment and academic performance of 1st-year nursing students were assessed between 2019 [prior to COVID-19, n = 195, (146 women)] and 2020 [during COVID-19, n = 180 (142 women)]. The independent sample t test or Mann-Whitney test was applied for a comparison between these two groups.

Results
There was no significant difference in student recruitment between 2019 and 2020. The overall performance of the first-year students improved in the Biochemistry, Immunopathology, Traditional Chinese Medicine Nursing and Combined Nursing courses via mandatory online teaching in 2020 compared with traditional teaching in 2019.

Conclusion
Suspension of in-class learning but continuing education virtually online has occurred without negatively impacting academic performance, thus academic goals are more than achievable in a complete lockdown situation. This study offers firm evidence to forge a path for developments in teaching methods to better incorporate virtual learning and technology in order to adapt to fast-changing environments. However, the psychological/psychiatric and physical impact of the COVID-19 lockdown and the lack of face-to-face interaction on these students remains to be explored.
Evaluaciones sobre la eficacia clínica de la ivermectina en el control de los pequeños estróngilos equinos (Cyathostoma spp). Status de susceptibilidad o resistencia en establecimientos del área central de la Argentina
Authors: Cooper Laura Gabriela , Paz Benard Benjamín José , Caffe Gabriel , Fernández Llanos Ignacio , Anziani Oscar Sergio 
Published: June 2023

Los pequeños estróngilos (o grupo Ciatostoma) comprenden a más de 50 especies y son los parásitos más comunes de los caballos adultos en todo el mundo. El control está basado en el uso masivo de antihelmínticos lo cual está permitiendo el desarrollo de fenómenos de resistencia. El Test de Reducción en el conteo de huevos (TRCH) es actualmente el método más utilizado para detectar la resistencia antihelmíntica, mientras que el Período de Reaparición de Huevos (PRH) puede actuar como un indicador temprano de la misma. Este estudio evaluó la actividad de lactonas macrocíclicas (ivermectina y moxidectina) en 192 equinos de 15 establecimientos del área central de la Argentina utilizando el TRCH y un modelo jerárquico Bayesiano para el análisis de los datos. La misma metodología se utilizó sobre la semana 7 post tratamiento para detectar posibles acortamientos en el PRH. La eficacia general de ambas lactonas evaluada 14 días post tratamiento fue muy alta en todos los establecimientos (99,8%-100 %) y en uno sólo de estos se observó un acortamiento del PRH. Es necesario un uso más selectivo de estas drogas para preservar su vida útil y demorar el desarrollo de resistencia.
Online-Ausstellungen. Bedeutung, Herausforderungen und Potenziale für Literaturarchive und Nachlassinstitutionen
Authors: Rettenwander Susanne 
Published: June 2023

Zusammenfassung
Der Beitrag widmet sich dem neuen Format der Online-Ausstellung mit besonderem Fokus auf die Bedeutung, die Herausforderungen und die Potenziale für Literaturarchive und Nachlassinstitutionen. Zudem werden die Online-Ausstellungen an der Österreichischen Nationalbibliothek (ÖNB) inhaltlich vorgestellt.
Proteins turn “Proteans” – The over 40-year delayed paradigm shift in structural biology: From “native proteins in uniquely defined configurations” to “intrinsically disordered proteins”
Authors: Frixione Eugenio , Ruiz-Zamarripa Lourdes 
Published: June 2023

Abstract
The current millennium brought up a revolutionary paradigm shift in molecular biology: many operative proteins, rather than being quasi-rigid polypeptide chains folded into unique configurations – as believed throughout most of the past century – are now known to be intrinsically disordered, dynamic, pleomorphic, and multifunctional structures with stochastic behaviors. Yet, part of this knowledge, including suggestions about possible mechanisms and plenty of evidence for the same, became available by the 1950s and 1960s to remain then nearly forgotten for over 40 years. Here, we review the main steps toward the classic notions about protein structures, as well as the neglected precedents of present views, discuss possible explanations for such long oblivion, and offer a sketch of the current panorama in this field.
Comparison and commutability study among four faecal immunochemical tests (FIT) systems
Authors: Deprez Liesbet , Piggott Carolyn , van der Hagen Eline A.E. , Frasa Marieke , Benton Sally C. 
Published: June 2023

Abstract

Objectives
Faecal immunochemical tests for haemoglobin (FIT) are used in colorectal cancer screening programs around the world and increasingly for triage of symptomatic patients. FIT results are currently not traceable to a common reference standard and results obtained on various FIT systems may not be equivalent. The size of the bias between the systems is difficult to quantify due to the complex pre-analytical aspects of FIT.

Methods
This study aimed to quantify the bias and the correlation between four FIT systems by measuring a panel of 38 faecal samples while limiting the effect of the pre-analytical aspects. In addition, the commutability of seven candidate reference materials (RM) was assessed.

Results
Pairwise method comparisons based on faecal samples demonstrated Pearson correlation coefficients ranging between 0.944 and 0.970 and an average proportional bias of −30 to −35 % for one FIT system compared to the other three. The relative standard deviation among biases of the individual samples was around 20 %. Due to these sample specific differences, no decisive conclusions could be drawn in the commutability study. However, two candidate RMs, prepared in the FIT system-specific storage/extraction buffers, had a better commutable profile than the other five.

Conclusions
The use of a common threshold for all FIT systems is currently not possible due to the presence of a proportional bias. We have identified potential commutable RMs to take to further studies on the production of a common calibrator, with the aim being to reduce the analytical bias observed on different FIT systems.
Perinatal, obstetric and parental risk factors for asthma in the offspring throughout childhood: a longitudinal cohort study
Authors: Caparros-Gonzalez Rafael A. , Essau Cecilia , Gouin Jean-Philippe , Pemau Andres , Galvez-Merlin Alejandra , de la Torre-Luque Alejandro 
Published: June 2023

Abstract

Objectives
Asthma is a common chronic and burdensome disease which typically begins in childhood. The aim of this study was to assess perinatal and obstetric factors which may increase the risk of developing asthma in the offspring.

Methods
Data from five consecutive waves (n=7,073 children, from birth to 15 years old) from a nationally-representative birth cohort of people born in the United Kingdom between 2000 and 2002, the Millennium Cohort Study (MCS), were used. The Kaplan–Meier survival curve was used to graphically display the risk of developing asthma from early childhood to adolescence. The Z-based Wald test was used to prove significant covariate loading.

Results
Cox regression analyzing the influence of covariates on asthma development risk showed a significant likelihood ratio test, χ2(18)=899.30, p<0.01. A parent with asthma (OR=2.02, p<0.01), a younger maternal age at delivery (OR=0.98, p<0.05), and the use of assisted reproductive technology (OR=1.43, p<0.05) were associated with an increased risk of developing asthma in the offspring.

Conclusions
Perinatal factors (a younger maternal age, assisted reproductive technology) and a parental factor (a parent with asthma) increased the risk for developing asthma in the offspring.
Velamentous cord insertion in monochorionic twin pregnancies: a step forward in screening for twin to twin transfusion syndrome and birthweight discordance?
Authors: Pinho Beatriz B. , Neves Mafalda , Pasion Rita , Matias Alexandra 
Published: June 2023

Abstract

Objectives
Two major complications of monochorionic diamniotic (MCDA) twin pregnancies are twin to twin transfusion syndrome (TTTS) and birthweight discordance. The current screening ultrasound test for these pathologies combines the detection of nuchal translucency discrepancy and abnormal ductus venosus in at least one twin, in the first trimester. We aim to determine whether combining the presence of velamentous cord insertion in at least one twin increases screening efficiency.

Methods
This was a retrospective cohort with a sample of 136 MCDA twin pregnancies followed at Centro Hospitalar Universitário São João, during a 16-year period.

Results
The combination of abnormal ductus venosus in at least one twin and nuchal translucency discrepancy is associated with the development of TTTS with an OR of 10.455, but not with birthweight discordance. The combination of these first trimester markers with velamentous cord insertion is not associated with the development of either outcome.

Conclusions
The presence of velamentous cord insertion in MCDA pregnancies is not associated to TTTS development. Therefore, the addition of this marker to the first trimester screening would not effectively predict the development of birthweight discordance or TTTS. However, a positive currently used screening test increases the risk of developing TTTS by about ten times.
Subjective well-being in informal caregivers during the COVID-19 pandemic
Authors: Guedes Daniela Alves , Gomes Nadirlene Pereira , Carvalho Amâncio António de Sousa 
Published: June 2023

Abstract
The study of subjective well-being (SWB) is important as it is related to the reduction of morbidity and mortality, with the maintenance of functionality and autonomy in the elderly population. The impact of the formative intervention on the SWB of informal caregivers (ICGs) during the pandemic crisis of COVID-19 was analyzed. This study is a quasi-experimental single-group, longitudinal study with a sample of 31 ICGs and their dependents. A form was used for data collection, and data processing was performed using IBM SPSS (Statistical Package for the Social Sciences), using descriptive statistics and inferential statistics. Of the total sample, the majority were female (90.3%). The difference between the mean of positive affection and negative affection at Moment 1 (M1) was –0.0581 ± 0.71590 and 0.04645 ± 0.53326 at Moment 2 (M2). The mean rank ordering of the difference between the two types of affection differed significantly between M2 and M1 (Wilcoxon: p < 0.000), with that of M2 being higher than M1 (16.93 > 2.50). The formative intervention, within the scope of community nursing, had a significant impact on increasing the SWB of the ICG in this sample. This study may contribute to improving the SWB of ICG and their dependents.
Effect on orofacial pain in patients with chronic pain participating in a multimodal rehabilitation programme – a pilot study
Authors: Holmström Anna-Karin , Vallin Simon , Wänman Anders , Lövgren Anna , Stålnacke Britt-Marie 
Published: June 2023

Abstract

Objectives
Orofacial pain in patients taking part in a multimodal rehabilitation programme (MMRP) due to chronic bodily pain is common but it is not known whether such a rehabilitation programme can also have an effect on the presence of orofacial pain. The first aim of this study was to evaluate the effect of an MMRP on orofacial pain frequency. The second aim was to evaluate differences in the effect on quality of life and on psychosocial factors related to chronic pain.

Methods
MMRP was evaluated through validated questionnaires from the Swedish Quality Registry for Pain Rehabilitation (SQRP). Fifty-nine patients participating in MMRP filled out the two screening questions for orofacial pain in addition to the SQRP questionnaires before and after participation in MMRP during the period August 2016 to March 2018.

Results
Pain intensity decreased significantly after the MMRP (p=0.005). Fifty patients (69.4 %) reported orofacial pain before MMRP and no significant decrease after the programme (p=0.228). Among individuals with orofacial pain, the self-reported level of depression decreased after participation in the programme (p=0.004).

Conclusions
Even though orofacial pain is common among patients with chronic bodily pain, participation in a multimodal pain programme was not enough to reduce frequent orofacial pain. This finding implies that specific orofacial pain management including information about jaw physiology could be a justified component of patient assessment prior to a multimodal rehabilitation programme for chronic bodily pain.
Neural Signatures of Hierarchical Linguistic Structures in Second Language Listening Comprehension
Authors: Lu Lingxi , Deng Yating , Xiao Zhe , Jiang Rong , Gao Jia-Hong 
Published: June 2023

AbstractNative speakers excel at parsing continuous speech into smaller elements and entraining their neural activities to the linguistic hierarchy at different levels (e.g., syllables, phrases, and sentences) to achieve speech comprehension. However, how a nonnative brain tracks hierarchical linguistic structures in second language (L2) speech comprehension and whether it relates to top-down attention and language proficiency remains elusive. Here, we applied a frequency-tagging paradigm in human adults and investigated the neural tracking responses to hierarchically organized linguistic structures (i.e., the syllabic rate of 4 Hz, the phrasal rate of 2 Hz, and the sentential rate of 1 Hz) in both first language (L1) and L2 listeners when they attended to a speech stream or ignored it. We revealed disrupted neural responses to higher-order linguistic structures (i.e., phrases and sentences) for L2 listeners in which the phrasal-level tracking was functionally related to an L2 subject’s language proficiency. We also observed less efficient top-down modulation of attention in L2 speech comprehension than in L1 speech comprehension. Our results indicate that the reduced δ-band neuronal oscillations that subserve the internal construction of higher-order linguistic structures may compromise listening comprehension in a nonnative language.