bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development and validation of gas chromatography with electron capture detection method using QuEChERS for pesticide residue determination in cucumber
Authors: Sofi Javid A. , Dar Alamgir A. , Jan Ishrat , Hassan Ghulam I. , Dar Shahnawaz R. , Mughal Arshad H. , Dar Naseer Ahmad 
Published: April 2023

AbstractA modified quick, easy, cheap, efficient, rugged, and safe (QuEChERS) method coupled to gas chromatography with electron capture detection was developed for the simultaneous determination of selected electronegative pesticides, namely, chlorpyrifos‐methyl (1), chlorpyrifos (2), quinolphos (3), profenofos (4), myclobutanil (5), ethion (6), fenpropathrin (7), and cypermethrin (8), in vegetables with high water content. The selected compounds and some of their metabolites have even been found in human body fluids. In addition, some of them are known or suspected carcinogens according to the World Health Organization. Extraction and cleanup parameters were optimized; thus, the original QuEChERS method was modified to minimize solvent usage by making the study eco‐friendly. The developed method was validated for selectivity, specificity, linearity, precision, and accuracy using SANTE guidelines. Calibration curves showed good linearity (r > 0.99) within the test range. Precision was evaluated by intra‐ and inter‐day experiments with an acceptable range of less than 20.0% of relative standard deviation. Recovery was evaluated at limit of quantification and was found to be in the range of 70–120%, with relative standard deviations lower than 4.21%. The proposed method is applicable for detection and monitoring of selected pesticides in one run not only in fruits and vegetables with high water content but also in samples containing large quantities of pigments/dyes.
China's manufacturing firms' willingness to pay for carbon abatement: A cost perspective
Authors: An Yunfei , Shi Xunpeng , Wang Qunwei , Yu Jian , Zhou Dequn , Zhou Xiaoyong 
Published: April 2023

AbstractThe existing studies of emissions reduction focus mainly on the technical potential and abatement costs while overlooking firms' willingness to pay (WTP) for emissions reduction. Yet WTP is a key parameter in a firm's decision to carry out emissions reduction while maximizing its profits. This paper estimates China's manufacturing industry (CMI) firms' maximum WTP for carbon abatement—defined as the cumulative product between the marginal abatement cost and corresponding abatement potential—using a large sample from a data envelopment analysis model. The results show that (a) the maximum WTP is significantly constrained by an isocost carbon abatement curve at RMB 8.65 million for the representative CMI firm; (b) the representative firms' WTP for carbon abatement varies among the sub‐sectors; and (c) profitability and production scales both positively affect firms' WTP for carbon abatement in all of CMI sub‐sectors, while innovation investment has a negative effect. The results suggest that the cost of carbon reduction technology for CMI firms should be below RMB 8.65 million for a representative CMI firm. The government should formulate subsidies or tax relief policies to help firms reduce their abatement costs. Further, the division of tasks in different sub‐sectors, between carbon emissions reduction on the one hand, and ongoing innovation on the other, should be clearly distinguished by policy bias to promote the transformation of industrial structure.
The cardioprotective effect of human glucagon‐like peptide‐1 receptor agonist (semaglutide) on cisplatin‐induced cardiotoxicity in rats: Targeting mitochondrial functions, dynamics, biogenesis, and redox status pathways
Authors: Atef Marwa Mohamed , Hafez Yasser Mostafa , El‐Deeb Omnia Safwat , Basha Eman H. , Ismail Radwa , Alshenawy Hanan , El‐Esawy Rasha Osama , Eltokhy Amira Kamel 
Published: April 2023

AbstractThe cardiotoxic effect of chemotherapeutic agents as cisplatin has become a major issue recently. Interference with mitochondrial dynamics, biogenesis, redox status, and apoptosis are the most possible underlying mechanisms. Semaglutide is a human glucagon‐like peptide‐1 receptor agonist (GLP‐1R), which is used primarily for the treatment of DM. Various recent studies have investigated (GLP‐1R) role in cardiovascular diseases due to antiapoptotic and antioxidant effects. The current study aimed to investigate the curative role of semaglutide's against cisplatin‐ induced cardiotoxicity and its relation to mitochondrial functions, dynamics, biogenesis, apoptosis, and redox status pathways. The study included 30 male rats divided into three groups: control, cisplatin‐induced cardiotoxicity, and cisplatin‐induced cardiotoxicity treated with semaglutide. At the end of the experiment heart index, serum cardiotoxicity markers, SOD, GPX activities and H2O2 level were estimated. Mitochondrial transmembrane potential, complex I and citrate synthase enzyme activities, ATP level, Mfn2 in addition to PGC‐1 α levels were assessed as biogenesis markers. Mitophagy markers PINK1 and Parkin mRNA gene expression were estimated. Histopathological examination of cardiac muscles of all studied groups and immunoassay of P53 and caspase 3 in cardiac tissue were examined to assess apoptosis. Cisplatin has disturbed mitochondrial function and dynamics, dysregulate redox status and induced mitophagy and apoptosis, in the other hand semaglutide treatment has normalized dysregulated mitochondrial function and dynamics, redox status and suppressed mitophagy and apoptosis. Semaglutide has ameliorative effect against cisplatin‐ induced cardiotoxicity via modulation of mitochondrial functions, dynamics, biogenesis, apoptosis, and redox status pathways.
SCF‐ChemBio: Chemical Biology Tour de France
Authors: Lopez Marie , Wong Yung‐Sing , Biot Christophe , Vauzeilles Boris 
Published: April 2023

AbstractChemical biology is a steadily growing field that has traditionally struggled to clearly define its boundaries in a short sentence. However, it can be stated that through the development of chemical and physicochemical tools, concepts and methods, chemical biology aims to address or stimulate biological questions at the molecular level in living organisms. Chemical biologists design and develop molecular tools that can probe or modulate biological processes, in order to understand their function, and sometimes to modify it for specific applications, but also to observe and analyze these tools in complex biological environments. Essentially positioned as a fundamental approach, chemical biology often remains very close to potential applications as it builds molecular objects capable of reacting to a significant biological stimulus. Chemical biology therefore finds natural development in fields such as health for the design of drugs and diagnostic systems or the environment for applications in crop science and ecology.
Electrochemical Oxidation and Functionalization of Low‐Density Polyethylene
Authors: Rahimzadeh Rasoul , Ortega‐Ramos Jessica , Haque Zenifar , Botte Gerardine G. 
Published: April 2023

AbstractPlastic waste is a serious environmental issue, and polyethylene (PE) is a significant component. The chemically inert nature of PE makes its recycling/upcycling process challenging. Thus, a novel method was demonstrated that enables the selective electrochemical functionalization and deconstruction of low‐density polyethylene (LDPE) by using low‐cost transition metal electrocatalysts at room temperature (23±2 °C) and low cell voltage (±1 V). Three different electrode and electrolyte combinations were studied for the oxidation of LDPE: copper metal/copper (II) ions, nickel metal/nickel (II) ions, and stainless steel/iron (II) and (III) ions. The copper and nickel electrode/electrolyte pairs showed a promising capability for oxidation and chain‐scission of LDPE. In contrast, the stainless‐steel and iron electrode/electrolyte pair showed no activity towards LDPE oxidation or depolymerization. The electrolysis of LDPE offers a new vista for the depolymerization and upcycling of plastics, further understanding of the process is needed.
The Interplay between Different Stimuli in a 4D Printed Photo‐, Thermal‐, and Water‐Responsive Liquid Crystal Elastomer Actuator
Authors: Cremonini Alessio , Sol Jeroen A. H. P. , Schenning Albert P. H. J. , Masiero Stefano , Debije Michael G. 
Published: April 2023

AbstractMulti‐stimuli responsivity in 3D‐printed objects is receiving much attention. However, the simultaneous interplay between different environmental stimuli is largely unexplored. In this work, we demonstrate direct ink writing of an oligomeric ink containing an azobenzene photo‐switch with an accessible hydrogen bond allowing triple responsivity to light, heat, and water. The resulting printed liquid crystal elastomer performs multiple actuations, the specific response depending on the environmental conditions. Bilayer films formed by printing on a static substrate can rapidly change shape, bending almost 80 degrees if irradiated in air or undergoing a shrinkage of about 50 % of its length when heated. The bilayer film assumes dramatically different shapes in water depending on combined environmental temperature and lighting conditions.
Deep Anomaly Detection on Tennessee Eastman Process Data
Authors: Hartung Fabian , Franks Billy Joe , Michels Tobias , Wagner Dennis , Liznerski Philipp , Reithermann Steffen , Fellenz Sophie , Jirasek Fabian , Rudolph Maja , Neider Daniel , Leitte Heike , Song Chen , Kloepper Benjamin , Mandt Stephan , Bortz Michael , Burger Jakob , Hasse Hans , Kloft Marius 
Published: April 2023

AbstractThis paper provides the first comprehensive evaluation and analysis of modern (deep‐learning‐based) unsupervised anomaly detection methods for chemical process data. We focus on the Tennessee Eastman process dataset, a standard litmus test to benchmark anomaly detection methods for nearly three decades. Our extensive study will facilitate choosing appropriate anomaly detection methods in industrial applications. From the benchmark, we conclude that reconstruction‐based methods are the methods of choice, followed by generative and forecasting‐based methods.
High serum magnesium is associated with lower risk of hepatocellular carcinoma among patients with nonalcoholic fatty liver disease
Authors: Yu Yi‐Chuan , Paragomi Pedram , Wang Renwei , Liang Feiran , Luu Hung N. , Behari Jaideep , Yuan Jian‐Min 
Published: April 2023

AbstractBackgroundNonalcoholic fatty liver disease (NAFLD) is a major contributor to the rising incidence of hepatocellular carcinoma (HCC). Magnesium is a major cation in cellular activities. Epidemiological data on magnesium level and its relation to HCC are sparse. This study aimed to examine the associations between serum levels of magnesium and the risk of HCC among patients with NAFLD.MethodsA total of 26,053 patients with NAFLD were identified in the University of Pittsburgh Medical Center Electronic Health Records from 2004 through 2018. After an average of 5.15 years of follow‐up, 395 patients developed HCC after the first measurement of serum magnesium. Cox proportional hazards regression model was used to calculate hazard ratios (HRs) and 95% CIs of HCC incidence associated with quartile levels of serum magnesium after adjustment for age, sex, race, body mass index, diuretics use, history of type 2 diabetes, history of hypertension, history of hyperlipidemia, and tobacco smoking.ResultsPatients with NAFLD who developed HCC had a significantly lower mean (± standard deviation) serum magnesium (0.769 ± 0.131 mmol/L) than those who remained free of HCC (0.789 ± 0.125 mmol/L; p = .003). Compared with the lowest quartile, the HRs (95% CIs) of HCC second, third, and fourth quartiles of serum magnesium were 0.87 (0.67–1.12), 0.77 (0.57–1.04), and 0.73 (0.56–0.96), respectively, after adjustment for multiple potential confounders (P
trend = .02).ConclusionThis finding suggests higher levels of serum magnesium were significantly associated with decreased risk of HCC among patients with NAFLD.
Missing finance in social impact bond research? A bibliometric overview between past and future research
Authors: Carè Rosella , Carè Stella , Lévy Nathalie , Fatima Rabia 
Published: April 2023

AbstractThis paper provides a bibliometric review of 156 articles published between 2011 and 2021 on social impact bonds (SIBs). We identified five research streams, namely studies that: (i) place the origins of SIBs in the neo‐liberalism framework; (ii) consider SIBs as an evolution of the new public management approach; (iii) focus on conceptualizing SIBs as an impact investment approach rooted in the social finance landscape; (iv) look at SIBs as a funding source for social entrepreneurship; and (v) detect an emerging phenomenon labeled as sustainable financial partnerships for the SDGs. Our results suggest that the current literature is strongly based on those that we have defined as a sort of UK influence, which is dominating the scientific perspective and the current use of SIBs, and that there is still less “finance‐based” research in this field. We conclude by proposing areas for future research.
Exact analysis of maximal ratio transmission‐based decode‐and‐forward relaying with arbitrary number of co‐channel interferers
Authors: Aladwani Awfa , Gucluoglu Tansal 
Published: April 2023

SummaryThis paper analyzes the performance of maximal ratio transmission (MRT)‐based cooperative communication system over Nakagami‐
fading channels in the existence of co‐channel interference which is becoming a critical factor since the limited spectrum bands are shared by growing number of devices. In particular, a dual‐hop decode‐and‐forward relaying is investigated when multiple interferers affect the relay and the destination nodes. Firstly, the cumulative distribution function (CDF) and the probability density function (PDF) of the signal‐to‐interference‐plus‐noise ratio (SINR) are derived. Then, the exact expressions for the outage probability (OP), average bit error probability (ABEP), and ergodic capacity are obtained. Furthermore, asymptotic expressions for OP and ABEP are provided to find the diversity and coding gains. Finally, simulation results are presented to validate our theoretical findings.
Extending single‐session interventions to target parents as agents of change in adolescent eating disorders
Authors: Loeb Katharine L. , Dimitropoulos Gina 
Published: April 2023

AbstractSchleider et al. (2023, International Journal of Eating Disorders, current issue) propose multiple applications of single‐session intervention (SSI) models to the eating disorders (EDs) intervention spectrum. In this commentary, we propose extending the potential of SSIs to target parents as agents of change for youth with restrictive EDs, particularly anorexia nervosa (AN). Directing SSIs to parents of children with AN can circumvent psychological barriers to care while capitalizing on the unique level of motivation in a parent to protect a child and advance their capacity to thrive. Key design components of effective SSIs map well onto the core principles of family‐based treatment (FBT), which can be distilled to inform the development of SSIs for parents of youth at risk or exhibiting emerging or diagnostic AN. The participatory action research framework highlighted by Schleider et al. (2023) speaks to the importance of developing SSIs using co‐design methodologies with parents. Doing so reflects the FBT principle of parent empowerment, acknowledges the research on parental self‐efficacy as a mediator of FBT, and recognizes parents as both key stakeholders in the prevention and treatment of child and adolescent EDs, and as the intended recipients of the SSIs created for this population.Public SignificanceSchleider et al. (2023, International Journal of Eating Disorders, current issue) propose multiple applications of single‐session intervention (SSI) models to eating disorders (EDs). In this commentary, we extend the potential of SSIs to target parents as agents of change for youth with restrictive EDs. Parent‐focused SSIs can circumvent psychological barriers to care while capitalizing on the unique level of motivation in a parent to advance their child's capacity to thrive.
Armed to the teeth: The underestimated diversity in tooth shape in snakes and its relation to feeding behavior and diet
Authors: Segall Marion , Houssin Céline , Delapré Arnaud , Cornette Raphaël , Herrel Anthony , Milgram Joshua , Shahar Ron , Dumont Maïtena 
Published: April 2023

AbstractThe structure, composition, and shape of teeth have been related to dietary specialization in many vertebrate species, but comparative studies on snakes' teeth are lacking. Yet, snakes have diverse dietary habits that may impact the shape of their teeth. We hypothesize that prey properties, such as hardness and shape, as well as feeding behavior, such as aquatic or arboreal predation, or holding vigorous prey, impose constraints on the evolution of tooth shape in snakes. We compared the morphology of the dentary teeth of 63 species that cover the phylogenetic and dietary diversity of snakes, using 3D geometric morphometrics and linear measurements. Our results show that prey hardness, foraging substrate, and the main feeding mechanical challenge are important drivers of tooth shape, size, and curvature. Overall, long, slender, curved teeth with a thin layer of hard tissue are observed in species that need to maintain a grip on their prey. Short, stout, less curved teeth are associated with species that undergo high or repeated loads. Our study demonstrates the diversity of tooth morphology in snakes and the need to investigate its underlying functional implications to better understand the evolution of teeth in vertebrates.
A novel electrochemical sensor based on AuNPs/Co‐CNs for the simultaneous detection of acetaminophen and 4‐aminophenol
Authors: Zhang Jinjin , Liu Wenjing , Wang Qi , Qu Jianying 
Published: April 2023

AbstractIn this work, two‐dimensional cobalt metal organic framework nanosheets (CoTP) were prepared by the simple hydrothermal reaction of cobalt nitrate hexahydrate with terephthalic acid, and then calcined at a high temperature under the environment of nitrogen to obtain cobalt carbon nanomaterials (Co‐CNs). The gold nanomaterials (AuNPs) were prepared by redox reaction. The prepared materials were characterized and analyzed by XRD, SEM and IR. A novel electrochemical sensor (AuNPs/Co‐CNs) was constructed successfully on a glassy carbon electrode combining Co‐CNs with AuNPs, which showed significant electrocatalytic activities for acetaminophen (PA) and 4‐aminophenol (4‐AP) and could be used to detect them simultaneously. Under the optimal conditions, the linear ranges for determination of PA and 4‐AP were 0.50–250.00 μM and 0.50–350.00 μM with the detection limits of 0.11 μM and 0.10 μM, respectively. Compared with other related reports, the proposed sensor exhibits a wider linear ranges, good sensitivity, accuracy and selectivity with potential applications in real sample analysis.
Reduction of hexavalent chromium using sulphonated polyether ether ketone as proton exchange membrane in microbial fuel cells
Authors: Gnanarathinam Vijay Samuel , Balakrishnan Abirami , Rajendran Govindarajan , Arivarasu Anitha , Dharmalingam Sangeetha , Thalaivarisai Balasundaram Sridharan , Narayanaswamy Venkatesan Prabhu , Ulagalantha Perumal Elaya Perumal 
Published: April 2023

AbstractHexavalent chromium (Cr(VI)) is a major source of environmental pollutants from tannery effluents. Reduction of hexavalent chromium was performed in a 500 mL working volume dual chamber microbial fuel cell (MFC). Synthetic wastewater containing Cr(VI) was used as anolyte and substrate for mixed microbial consortia to release electrons. The ions produced were transferred to cathodic chamber via a Proton Exchange Membrane (PEM). In this study, sulphonated polyether ether ketone (SPEEK) was used as PEM and compared with Nafion 117 for Cr(VI) reduction. The microbial consortia that aided the treatment were isolated and identified to belong to Enterobacter, Acinetobacter, Stenotrophomonas and Pseudomonas species. The Cr(VI) reduction observed were 14.4% and 51% for MFCs with Nafion 117 and SPEEK as PEM, respectively. The wastewater analysis also showed improved percentage removal for SPEEK than for Nafion 117. The cost analysis shows that Nafion was 2 times higher than SPEEK to be used as PEM. This study highlights that SPEEK as PEM in MFC will be an efficient method for reduction of Cr(VI) from tannery effluents.
Global climate change and commodity markets: A hedging perspective
Authors: Jia Shanghui , Chen Xinhui , Han Liyan , Jin Jiayu 
Published: April 2023

AbstractThis paper aims to measure the tail‐risk dependence between climate change and commodity futures markets. We utilize Morgan Stanley Capital International Climate Change Index (CCI) to serve as a proxy indicator of the stock market climate change for examining the tail‐risk spillover effect among 16 major commodity futures. Using GARCH–Copula–CoVaR framework, we show that extreme climate change has a significant tail‐risk spillover effect on commodity futures markets, in which agricultural and energy futures are affected by climate change most. We then adopt the copula‐based generalized autoregressive conditional heteroskedasticity (GARCH) model to compute the optimal hedge ratio among each pair of CCI with commodity futures, which performs well economic advantages for all 16 commodities. Compared with hedging against commodity index, CCI has a more significant hedging effect on metal and energy subindex futures. Therefore, we finally suggest an effective hedging portfolio composed of CCI and subindex futures in a significant economic sense.
The relationship between resting‐state amplitude fluctuations and memory‐related deactivations of the default mode network in young and older adults
Authors: Kizilirmak Jasmin M. , Soch Joram , Schütze Hartmut , Düzel Emrah , Feldhoff Hannah , Fischer Larissa , Knopf Lea , Maass Anne , Raschick Matthias , Schult Annika , Yakupov Renat , Richter Anni , Schott Björn H. 
Published: April 2023

AbstractThe default mode network (DMN) typically exhibits deactivations during demanding tasks compared to periods of relative rest. In functional magnetic resonance imaging (fMRI) studies of episodic memory encoding, increased activity in DMN regions even predicts later forgetting in young healthy adults. This association is attenuated in older adults and, in some instances, increased DMN activity even predicts remembering rather than forgetting. It is yet unclear whether this phenomenon is due to a compensatory mechanism, such as self‐referential or schema‐dependent encoding, or whether it reflects overall reduced DMN activity modulation in older age. We approached this question by systematically comparing DMN activity during successful encoding and tonic, task‐independent, DMN activity at rest in a sample of 106 young (18–35 years) and 111 older (60–80 years) healthy participants. Using voxel‐wise multimodal analyses, we assessed the age‐dependent relationship between DMN resting‐state amplitude (mean percent amplitude of fluctuation, mPerAF) and DMN fMRI signals related to successful memory encoding, as well as their modulation by age‐related hippocampal volume loss, while controlling for regional grey matter volume. Older adults showed lower resting‐state DMN amplitudes and lower task‐related deactivations. However, a negative relationship between resting‐state mPerAF and subsequent memory effect within the precuneus was observed only in young, but not older adults. Hippocampal volumes showed no relationship with the DMN subsequent memory effect or mPerAF. Lastly, older adults with higher mPerAF in the DMN at rest tend to show higher memory performance, pointing towards the importance of a maintained ability to modulate DMN activity in old age.