bluuebunny/crossref_metadata_2025_split huggingface dataset:
Monitoring of sustainable land management using remotely sensed vegetation cover and variable tolerable soil erosion targets across New South Wales, Australia
Authors: Gray Jonathan M. , Leys John F. , Yang Xihua , Zhang Mingxi 
Published: December 2022

AbstractThe monitoring of land management practices is vital for the protection of soil resource and the environment. Here, we present a new approach to monitor sustainable land management using widely available remotely sensed data, such as MODIS fractional vegetation cover data. The method is based on the concept of maintaining sufficient vegetation cover to prevent hillslope water erosion beyond tolerable soil erosion targets. The targets were based on long‐term natural erosion rates plus a small constant and are spatially and temporally variable, not static as in most reported studies to date. Where vegetation cover is more than that required to prevent nontolerable erosion under normal conditions for that calendar month, the site (pixel) is deemed to be managed sustainably. Monthly indices are then combined to form a yearly sustainable land management index (SLMI), presented as raster maps with a spatial resolution of 100 m. We explored this new method through case studies over New South Wales (NSW), Australia, over the period 2010 to 2021, with a particular examination of 2020. Results were further stratified by land uses and natural resource management regions, which revealed useful data and trends. The method is offered as an example of the potential use of readily available vegetation cover data to quantitatively assess and monitor levels of sustainable land management across landscapes. We believe it overcomes the limitations of previous methods to monitor vegetation cover and land management from remote‐sensed data alone. Other users are encouraged to adapt the broad approach to meet local requirements.
The Aronsson equation for absolute minimizers of supremal functionals in Carnot–Carathéodory spaces
Authors: Pinamonti Andrea , Verzellesi Simone , Wang Changyou 
Published: December 2022

AbstractGiven a family of vector fields which induces a continuous Carnot–Carathéodory distance, we show that any absolute minimizer of a supremal functional defined by a quasiconvex Hamiltonian , allowing ‐variable dependence, is a viscosity solution to the Aronsson equation
Functional basis for calmodulation of the TRPV5 calcium channel
Authors: Zuidscherwoude Malou , van Goor Mark K. , Roig Sara R. , Thijssen Niky , van Erp Merijn , Fransen Jack , van der Wijst Jenny , Hoenderop Joost G. 
Published: December 2022

AbstractWithin the transient receptor potential (TRP) superfamily of ion channels, TRPV5 is a highly Ca2+‐selective channel important for active reabsorption of Ca2+ in the kidney. Its channel activity is controlled by a negative feedback mechanism involving calmodulin (CaM) binding. Combining advanced microscopy techniques and biochemical assays, this study characterized the dynamic lobe‐specific CaM regulation. We demonstrate for the first time that functional (full‐length) TRPV5 interacts with CaM in the absence of Ca2+, and this interaction is intensified at increasing Ca2+ concentrations sensed by the CaM C‐lobe that achieves channel pore blocking. Channel inactivation occurs without requiring CaM N‐lobe calcification. Moreover, we show a Ca2+‐dependent binding stoichiometry at the single channel level. In conclusion, our study proposes a new model for CaM‐dependent regulation – calmodulation – of this uniquely Ca2+‐selective TRP channel TRPV5 that involves apoCaM interaction and lobe‐specific actions, which may be of significant physiological relevance given its role as gatekeeper of Ca2+ transport in the kidney.
imageKey points
The renal Ca2+ channel TRPV5 is an important player in maintenance of the body's Ca2+ homeostasis.
Activity of TRPV5 is controlled by a negative feedback loop that involves calmodulin (CaM), a protein with two Ca2+‐binding lobes.
We investigated the dynamics of the interaction between TRPV5 and CaM with advanced fluorescence microscopy techniques.
Our data support a new model for CaM‐dependent regulation of TRPV5 channel activity with CaM lobe‐specific actions and demonstrates Ca2+‐dependent binding stoichiometries.
This study improves our understanding of the mechanism underlying fast channel inactivation, which is physiologically relevant given the gatekeeper function of TRPV5 in Ca2+ reabsorption in the kidney.
Simulations of cortical networks using spatially extended conductance‐based neuronal models
Authors: Haufler Darrell , Ito Shinya , Koch Christof , Arkhipov Anton 
Published: December 2022

AbstractThe Hodgkin–Huxley model of action potential generation and propagation, published in the Journal of Physiology in 1952, initiated the field of biophysically detailed computational modelling in neuroscience, which has expanded to encompass a variety of species and components of the nervous system. Here we review the developments in this area with a focus on efforts in the community towards modelling the mammalian neocortex using spatially extended conductance‐based neuronal models. The Hodgkin–Huxley formalism and related foundational contributions, such as Rall's cable theory, remain widely used in these efforts to the current day. We argue that at present the field is undergoing a qualitative change due to new very rich datasets describing the composition, connectivity and functional activity of cortical circuits, which are being integrated systematically into large‐scale network models. This trend, combined with the accelerating development of convenient software tools supporting such complex modelling projects, is giving rise to highly detailed models of the cortex that are extensively constrained by the data, enabling computational investigation of a multitude of questions about cortical structure and function.
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Improving paediatric antimicrobial stewardship in remote and regional Queensland hospitals: development and qualitative evaluation of a tailored intervention for intravenous-to-oral antibiotic switching
Authors: Sharman Leah S , Avent Minyon L , Lyall Vivian , Fejzic Jasmina , Clark Julia E , Irwin Adam , Graham Nicolette , van Driel Mieke L 
Published: December 2022

ObjectivesTimely intravenous-to-oral antibiotic switching for children is important for paediatric antimicrobial stewardship (AMS). However, low decision-making confidence and fragmentation of patient care can hamper implementation, with difficulties heightened regionally where AMS programmes for children are lacking. The aim of this study was to develop and evaluate user-led creation and implementation of an intervention package for early intravenous-to-oral switching at regional hospitals in Queensland, Australia.DesignGuided by theory, a four-phase approach was used to: (1) develop multifaceted intervention materials; (2) review materials and their usage through stakeholders; (3) adapt materials based on user-feedback and (4) qualitatively evaluate health workers experiences at 6 months postintervention.SettingSeven regional hospitals in Queensland, Australia.ParticipantsPhase 2 included 15 stakeholders; health workers and patient representatives (patient-guardians and Indigenous liaison officers). Phase 4 included 20 health workers across the seven intervention sites.ResultsContent analysis of health worker and parent/guardian reviews identified the ‘perceived utility of materials’ and ‘possible barriers to use’. ‘Recommendations and strategies for improvement’ provided adjustments for the materials that were able to be tailored to individual practice. Postintervention interviews generated three overarching themes that combined facilitators and barriers to switching: (1) application of materials, (2) education and support, and (3) team dynamics. Overall, despite difficulties with turnover and problems with the medical hierarchy, interventions aided and empowered antibiotic therapy decision-making and enhanced education and self-reflection.ConclusionsDespite structural barriers to AMS for switching from intravenous-to-oral antibiotics in paediatric patients, offering a tailored multifaceted intervention was reported to provide support and confidence to adjust practice across a diverse set of health workers in regional areas. Future AMS activities should be guided by users and provide opportunities for tailoring tools to practice setting and patients’ requirements.
Hospital-based patient navigation programs for patients who experience injury-related trauma and their caregivers: a scoping review
Authors: Doucet Shelley , Luke Alison , Anthonisen Grailing 
Published: December 2022

ObjectiveThis review’s objective is to map the literature on the characteristics, impact, barriers and facilitators of hospital-based patient navigation programmes that support patients who experience injury-related trauma and their caregivers. Patients who experience injury-related trauma frequently require support from multiple care teams and face many challenges to care, both in hospital and when transitioning across settings and services. Patient navigation can improve their care.DesignThis review is conducted according to JBI methodology for scoping reviews. The initial database search took place on 6 June 2021 and the grey literature search took place between September and October 2021. The results are presented in a Preferred Reporting Items for Systematic Reviews and Meta-analyses for Scoping Reviews flow diagram.SettingThis review considered materials where the patient navigation programmes were delivered in hospital settings. There was no geographical limit to this study.ParticipantsThis review focused on hospital-based patient navigation programmes for patients who experience injury-related trauma and/or their caregivers.ResultsThis review captured 11 records that describe 10 programmes. All programmes were based in the USA. Most programmes provided education, care coordination, discharge planning, and referrals to resources, services, and programmes to assist patients and/or their families in the hospital or the community. Half the programmes were based in level 1 trauma centres. Common impacts included decreases in readmission rates and increases in satisfaction rates. Barriers included difficulty recruiting or enrolling patients with short hospital stays and hospital administrators’ and healthcare providers’ lack of understanding of the navigator role. Navigator background, either professional or experiential, was identified as a facilitator, as was flexibility in programme delivery and communication methods.ConclusionsEleven records show a small but distinct sample. Reported characteristics, impact, barriers and facilitators were consistent with findings from other patient navigation studies. The results can inform the development and implementation of similar programmes in trauma centres and support changes in policy to improve the delivery of care.
Incidence and characteristics of adverse events in paediatric inpatient care: a systematic review and meta-analysis
Authors: Dillner Pernilla , Eggenschwiler Luisa C , Rutjes Anne W S , Berg Lena , Musy Sarah N , Simon Michael , Moffa Giusi , Förberg Ulrika , Unbeck Maria 
Published: December 2022

BackgroundAdverse events (AEs) cause suffering for hospitalised children, a fragile patient group where the delivery of adequate timely care is of great importance.ObjectiveTo report the incidence and characteristics of AEs, in paediatric inpatient care, as detected with the Global Trigger Tool (GTT), the Trigger Tool (TT) or the Harvard Medical Practice Study (HMPS) method.MethodMEDLINE, Embase, Web of Science and Google Scholar were searched from inception to June 2021, without language restrictions. Studies using manual record review were included if paediatric data were reported separately. We excluded studies reporting: AEs for a specific disease/diagnosis/treatment/procedure, or deceased patients; study protocols with no AE outcomes; conference abstracts, editorials and systematic reviews; clinical incident reports as the primary data source; and studies focusing on specific AEs only. Methodological risk of bias was assessed using a tool based on the Quality Assessment Tool for Diagnostic Accuracy Studies 2. Primary outcome was the percentage of admissions with ≥1 AEs. All statistical analyses were stratified by record review methodology (GTT/TT or HMPS) and by type of population. Meta-analyses, applying random-effects models, were carried out. The variability of the pooled estimates was characterised by 95% prediction intervals (PIs).ResultsWe included 32 studies from 44 publications, conducted in 15 countries totalling 33 873 paediatric admissions. The total number of AEs identified was 8577. The most common types of AEs were nosocomial infections (range, 6.8%–59.6%) for the general care population and pulmonary-related (10.5%–36.7%) for intensive care. The reported incidence rates were highly heterogeneous. The PIs for the primary outcome were 3.8%–53.8% and 6.9%–91.6% for GTT/TT studies (general and intensive care population). The equivalent PI was 0.3%–33.7% for HMPS studies (general care). The PIs for preventable AEs were 7.4%–96.2% and 4.5%–98.9% for GTT/TT studies (general and intensive care population) and 10.4%–91.8% for HMPS studies (general care). The quality assessment indicated several methodological concerns regarding the included studies.ConclusionThe reported incidence of AEs is highly variable in paediatric inpatient care research, and it is not possible to estimate a reliable single rate. Poor reporting standards and methodological differences hinder the comparison of study results.
Effects of PCSK9 Inhibition on Coronary Atherosclerosis Regression of Nontarget Lesions after Primary Percutaneous Coronary Intervention in Acute Coronary Syndrome Patients
Authors: Li Yongjun , Yang Mingming , Chen Xi , Zhang Rui , Li Jing , Zhang Xiaoguo , Zuo Pengfei , Ma Genshan 
Published: December 2022

Aims. To evaluate the regression of coronary atherosclerosis with proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibition in acute coronary syndrome (ACS) patients following primary percutaneous coronary intervention (PPCI). Methods and Result. We examined 40 nontarget lesions in 17 ACS patients who underwent PPCI and were treated with PCSK9 inhibitors. At 1 year, total cholesterol, low-density lipoprotein cholesterol (LDL-C), and atherogenic index (AI) decreased significantly by 2.5 mmol/L, 2.01 mmol/L, and 1.86, respectively. On quantitative coronary angiography, treatment with PCSK9 inhibitors reduced significantly the atherosclerotic area stenosis in nontarget lesions (61.18 ± 14.55 at baseline vs. 52.85 ± 15.51 at 1 year,

P

< 0.001). Conclusions. After 1 year of PCSK9 inhibition treatment for ACS patients, the area stenosis of non-TLR was considerably reduced.
Middle Meningeal Artery Embolization to Treat Chronic Subdural Hematoma
Authors: Rudy Robert F. , Catapano Joshua S. , Jadhav Ashutosh P. , Albuquerque Felipe C. , Ducruet Andrew F. 
Published: December 2022

Background
Chronic subdural hematoma is associated with high rates of perioperative complications and recurrence.

Methods
The classic treatments are observation or surgical evacuation. Middle meningeal artery embolization is a recently emerging procedure that has evolved as the neuroendovascular community has gained collective experience. This review summarizes the pathophysiology of chronic subdural hematoma, reviews the classic treatment strategies, discusses the advent and use of middle meningeal artery embolization, and describes the contemporary technical approach to middle meningeal artery embolization.

Results
Embolization has the advantages of targeting the vascular supply of the neomembranes implicated in chronic subdural hematoma pathophysiology and avoiding surgical or bedside drainage in a population associated with significant comorbidities.

Conclusions
Middle meningeal artery embolization is increasingly used both as an adjunct treatment to surgical evacuation and as a stand‐alone method for managing this challenging entity.
Artemidorus, Dream Exegesis, and the Case of the Interpolating Expert Dreamer
Authors: Hall Claire 
Published: December 2022

Abstract
This article makes the following case: according to Artemidorus of Daldis’ Oneirocriticon one main task of the dream interpreter is to identify, through knowledge of the dreamer, which components of a dream are internal in order to assess—as far as possible—the external components of a dream. I argue that very similar hermeneutic issues were being extensively theorised in Artemidorus’ period by Jewish and Christian writers who were concerned with the problem of prophetic interpolation: in particular, cases in the Bible in which prophecies do not come true. In making this comparison, I hope to clarify a number of features of Artemidorus’ hermeneutic, including the relationship between the origin and structure of dreams and the exegetical practice of the dream-interpreter.
Dis/Ability: A Discussion on Creating More Accessible Employment for Assistance Dog Instructors with Disabilities
Authors: Warda Tiamat 
Published: December 2022

Abstract
Disabled individuals can and do lead successful careers as assistance dog instructors. However, the international percentage of professional disabled instructors is significantly lower than their able-bodied colleagues. This paper takes an initial step in questioning the benefits and challenges of creating more accessible and inclusive career paths for disabled assistance dog instructors, hopefully acting as a springboard for future research, and initiating conversation within the assistance dog sector itself, as well. Some disabled individuals may have a disability, or combinations of more than one, which could challenge the welfare and wellbeing of the dogs they educate. Others may have a greater aptitude for educating assistance dogs and offering deeper empathy at times. This paper was inspired by the author’s six years working as a guide dog instructor. It questions what the implications of a disabled trainer’s career might be for the disabled individual, assistance dog, employer, and client.
How to Make the Moment Last?
Authors: Plaetzer Niklas 
Published: December 2022

Abstract
Massimiliano Tomba’s Insurgent Universality traces a global history of revolutionary institution-building as ‘theory in action’, pushing radical democracy beyond an ontology of the political. This contribution aims to clarify the place of ‘insurgent institutions’ in Tomba’s work and suggests that an unresolved tension persists between insurgent universality as popular institutions on the one hand, and as a negative dis-ordering on the other. Exploring the promise and limitations of ‘insurgent institutions’ in light of their durability, its first part reads Insurgent Universality alongside Santi Romano, the legal pluralist whose concept of the institution Tomba adopts. Secondly, the article turns to Hannah Arendt’s understanding of authority and Miguel Abensour’s discussion of ‘insurgent institutions’ as two potentially helpful accounts of democratic practice within durational time. Where Tomba remains focused on constellations between moments of rupture, Arendt and Abensour offer a politically generative understanding of durability specific to radical-democratic institutions.
K.H. Miskotte’s Efforts toward a Renewed Relationship with Judaism
Authors: Reeling Brouwer Rinse H. 
Published: December 2022

Abstract
K.H. Miskotte’s dissertation on The Essence of Judaism (1932) at once involved constructing a phenomenological Wesensschau, preparation for Jewish-Christian encounter, and engagements in intra-Protestant disputes. Around the Second World War, Miskotte’s writings simultaneously showed unconditional solidarity with the persecuted Jewish people and warned against Jewish influences on Protestantism. At the end of his life, Miskotte reflected with distress on the book of Rabbi Ignaz Maybaum, The Face of God after Auschwitz, and he returned to his initial judgment on liberal Judaism.
The Making of Christian Toryism: The Public Faith of Harold Macmillan
Authors: Wood Benjamin J. 
Published: December 2022

Abstract
This article considers the significance of the public Christianity of the British Prime Minister Harold Macmillan (1894–1986). By excavating the socially conscious faith of the Edwardian upper classes, it locates Macmillan as the advocate of a unique synthesis of Disraelian Toryism and Christian Socialism. The discussion opens with an exploration of the origins of Macmillan’s politics. Drawing on the medievalism of William Morris, the Anglo-Catholicism of Ronald Knox, and Augustinian pessimism, Macmillan arrives at a sin-sensitive politics which seeks to tame capital and the state. The argument then considers how Macmillan’s rich articulation of Toryism has the capacity to challenge contemporary British Conservatives to recover and deepen their traditions of community-spirit and social justice. In an effort to contest a narrow description of British Toryism as a purely economic theory, I argue for a generous reassessment of a profoundly religious Toryism
Demonstratives in Musandam Arabic: Distinctive Archaisms and Innovations
Authors: Anonby Erik , Bettega Simone , Procházka Stephan 
Published: December 2022

Abstract
This study introduces and analyzes proximal and distal singular demonstratives in fourteen varieties of Musandam Arabic, a little-documented dialect group located on Musandam Peninsula in northern Oman and neighbouring areas of the United Arab Emirates. Following an overview of the dialect group in its regional context, the study provides a description of singular demonstratives from the point of view of phono-logy, morphology, and geographical distribution. The study then focuses on two salient features found in several of the varieties under investigation: gender distinction based on consonantal alternation (d-based masculine forms vs t-based feminine forms); and gemination of the feminine t-element. While the former is attested, albeit rarely, in other Arabic dialects, the latter is unheard of. In the last section of the article, some hypotheses are put forward as to how these forms could have developed from a historical point of view, in light of data from different Arabic and Semitic varieties. While the gemination of the t-element is best regarded as a Musandam-internal innovation, the d : t consonantal alternation reinforces the putative historical link between south-western Arabia and Oman.
“Rescued Women”
Authors: Isgrigg Daniel D. 
Published: December 2022

Abstract
This article traces the history of early pentecostal responses to sex trafficking and the related issue of prostitution. It documents the stories of Pentecostal Rescue missions recorded in pentecostal papers such as The Bridegroom’s Messenger, Apostolic Faith, Weekly Evangel, and the Pentecostal Holiness Advocate. This study explores pentecostal views of society and culture as well as rhetoric about trafficked women, especially the concepts of victimhood, guilt, and culpability for “fallen women.” It demonstrates how ministry to trafficked women positively and negatively shaped pentecostal attitudes toward women and dress in the pentecostal tradition.