bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sex differences in wrist torque and endurance—Biomechanical factors associated with developing lateral epicondylitis of the humerus
Authors: Ikeda Kazuhiro , Yoshii Yuichi , Kohyama Sho , Ikumi Akira , Ikeda Reimi , Yamazaki Masashi 
Published: December 2022

AbstractSince eccentric contractions contribute to the development of tendinopathy, sex differences in wrist torque and endurance may be involved in the pathophysiology of lateral epicondylitis and its refractoriness. Therefore, the present study investigated sex differences in wrist torque and endurance. The wrist extension and flexion torques of the 100 wrists of 25 males and 25 females were measured. The following parameters were assessed: muscle strength at the starting‐ and end point for the measurement, Δ muscle strength, that is, the amount of a loss over time, and the muscle endurance ratio, that is, the decrease rate over time. Each parameter in males and females was statistically analyzed. In wrist extension, muscle strength at the starting point was 6.1 Nm for males and 3.3 Nm for females (p < 0.001); Δ Muscle strength was −0.052 Nm/s for males and −0.038 Nm/s for females (p = 0.036); The muscle endurance ratio was 99.1%/s for males and 98.8%/s for females (p = 0.015). In wrist flexion, muscle strength at the starting point and absolute value of Δ muscle strength were significantly larger in males than in females; No significant difference was observed in the muscle endurance ratio in wrist flexion between males and females. These results revealed sex differences in wrist torque and endurance. The muscle endurance ratio of the wrist extensors was lower in females than in males, which suggests that females need to exert more effort to maintain the wrist extension position under resistance. This may predispose the wrist extensor muscles in females to eccentric contractions.
Lack of radiosensitivity predicts poor disease specific survival in myxoid liposarcoma
Authors: Houdek Matthew T. , Mallett Katherine E. , Heidenreich Mark J. , Ahmed Safia K. , Wenger Doris E. , Smith John‐Rudolph H. , Siontis Brittany L. , Robinson Steven I. , Folpe Andrew L. , Petersen Ivy A. , Rose Peter S. 
Published: December 2022

AbstractBackgroundCompared to other sarcomas, myxoid liposarcoma (ML) is known to be radiosensitive, with improved oncologic outcomes. Although these tumors “shrink” following radiotherapy, there is a paucity of data examining the degree of radiosensitivity and oncologic outcome. The purpose of the study was to evaluate pre‐ and postradiotherapy tumor volume to determine if size reduction impacts outcome.MethodsWe reviewed 62 patients with ML undergoing surgical resection combined with preoperative radiotherapy, with pre‐ and postradiotherapy MRI. This included 34 (55%) males, with a mean age of 47 ± 14 years. All tumors were deep to the fascia, and 12 (19%) patients had tumors with a >5% round‐cell component.ResultsThe mean volume reduction was 54% ± 29%. Compared to patients with >25% volume reduction, patients with reduction ≤25% had worse 10‐year disease specific survival (86% vs. 37%, p < 0.01), in addition to an increased risk of metastatic disease (HR 4.63, p < 0.01) and death due to disease (HR 4.52, p < 0.01).ConclusionLack of volume reduction is a risk factor for metastatic disease and subsequent death due to disease in patients with extremity ML treated with combined preoperative radiotherapy and surgery. This data could be used to stratify patients for adjuvant therapies and follow‐up intervals.
Colloidal Quantum Dots: Synthesis, Composition, Structure, and Emerging Optoelectronic Applications
Authors: Zhang Jian , Zhang Shaohui , Zhang Yule , Al‐Hartomy Omar A. , Wageh Swelm , Al‐Sehemi Abdullah G. , Hao Yabin , Gao Lingfeng , Wang Hao , Zhang Han 
Published: December 2022

AbstractIn recent decades, quantum dots (QDs) with tunable bandgap, large absorption coefficient, high quantum yield, multiexciton effect, and easy solution processing have unparalleled advantages in photoelectric conversion. Optoelectronic devices based on QDs of different composition have made great progress. However, there is still a lack of reviews on comparing the optoelectronic application level of semiconductor quantum dots (SQDs), perovskite quantum dots (PQDs), and carbon quantum dots (CDs), and also rarely providing a comprehensive summary of photocatalysis. First, this review almost completely summarizes advantages and disadvantages of common synthesis methods for QDs, especially pointing out the importance of optimization strategies for preparing high‐quality QDs such as ligand engineering, ion exchange, and purification separation. Then, compositions of SQD, PQD, CD, and corresponding optoelectronic properties are introduced, respectively. Next, the strengths and weaknesses of the four QDs structures are compared in detail. Finally, the flourishing development in various optoelectronic applications is separately demonstrated, and development degree of SQDs, PQDs, and CDs is compared to discover the most suitable application scenarios for each. On these bases, bottlenecks and opportunities are also put forwarded, hoping to stimulate more breakthroughs in this field.
Corrosion behavior and kinetics model of rare earth low‐alloy steel in a soil simulation solution
Authors: Zhang Jinling , Dong Yuanneng , Ding Cong , Yu Yanchong , Wang Shebin 
Published: December 2022

AbstractThe corrosion behavior of rare earth (RE) low‐alloy steel in soil simulation solution was investigated by immersion test, electrochemical experiment, scanning electron microscopy, and X‐ray diffraction, compared with Q450 weathering steel. The kinetics model of all steels in soil simulation solution was established. The pitting corrosion mechanism of nonmetallic and RE inclusions was discussed. The results revealed that the RE improved the corrosion resistance of low‐alloy steel by modifying inclusions and promoting the formation of a dense protective film. The steel containing 0.0047% RE achieved the best corrosion resistance. The corrosion product layers were mainly composed of γ‐FeOOH, α‐FeOOH, Fe3O4, and Fe(OH)3. The results of the kinetic model showed that the dissolution of the anode was the restricted link of the whole process. The lowest apparent corrosion rate constant k of the sample containing 0.0047% RE was 2.359 × 10−4 μm/h in the soil simulation solution. The kinetic model could serve as a method to predict the service life of steel parts.
Influence of Tacticity on the Structure Formation of Poly(methacrylic acid) in Langmuir/Langmuir–Blodgett and Thin Films
Authors: Hasan Nazmul , Nguyen Thi Minh Hai , Busse Karsten , Kressler Jörg 
Published: December 2022

AbstractA perfect isotactic poly(methacrylic acid) (it‐PMAA) is synthesized and characterized by NMR spectroscopy. Surface pressure versus mean area per repeat unit (π−A) isotherms are recorded and compared with atactic poly(methacrylic acid) (at‐PMAA). it‐PMAA exhibits a π−A isotherm, indicating the formation of a stable Langmuir film. The isotherm has a characteristic pseudo‐plateau at π of ≈11–14 mN m−1 attributed to the creation of worm‐like entities confirmed by atomic force microscopy (AFM) in Langmuir–Blodgett (LB) films. These structures transform into spherical nanoparticles of ≈40 to 80 nm seen in LB films transferred at the end of the pseudo‐plateau of the isotherm. Grazing incidence wide‐angle X‐ray scattering (GI‐WAXS) shows a broad scattering signal (halo‐like) at a q position of ≈11.12 nm−1, revealing the amorphous nature of the nanoparticles. An ordered morphology, however, is observed in thin films prepared by precipitating it‐PMAA from dimethylformamide (DMF) solution under vigorous stirring and coating them on a solid support. Optical microscopy (OM), AFM, and GI‐WAXS reveal more details about the structure. Finally, various structural modifications of PMAAs are explained based on their tacticity and the subsequent hydrogen bonding effects between the carboxylic acid groups.
Three‐Dimensional Mesh Recovery from Common 2‐Dimensional Pictures for Automated Assessment of Body Posture in Camptocormia
Authors: Wolke Robin , Gavriliuc Olga , Granert Oliver , Deuschl Günther , Margraf Nils G. 
Published: December 2022

ABSTRACTBackgroundThree‐dimensional (3D) human body estimation from common photographs is an evolving method in the field of computer vision. It has not yet been evaluated on postural disorders. We generated 3D models from 2‐dimensional pictures of camptocormia patients to measure the bending angle of the trunk according to recommendations in the literature.MethodsWe used the Part Attention Regressor algorithm to generate 3D models from photographs of camptocormia patients' posture and validated the resulting angles against the gold standard. A total of 2 virtual human models with camptocormia were generated to evaluate the performance depending on the camera angle.ResultsThe bending angle assessment using the 3D mesh correlated highly with the gold standard (R = 0.97, P < 0.05) and is robust to deviations of the camera angle.ConclusionsThe generation of 3D models offers a new method for assessing postural disorders. It is automated and robust to nonperfect pictures, and the result offers a comprehensive analysis beyond the bending angle.
Using Downgaze Palsy Progression Rate to Model Survival in Progressive Supranuclear Palsy–Richardson Syndrome
Authors: Xie Tao , Wills Anne‐Marie , Liao Chuanhong , Dale Marian L. , Ramsden David B. , Padmanaban Mahesh , Abou Chaar Widad , Pantelyat Alexander , Golbe Lawrence I. 
Published: December 2022

ABSTRACTBackgroundRapid development of downgaze palsy, the most specific symptom of progressive supranuclear palsy (PSP), has been associated with shorter survival in small studies.ObjectiveWe hypothesized that the progression rate of downgaze palsy and other disease features could predict survival if assessed soon after the onset of downgaze palsy in a large data set.MethodsWe used a longitudinal database of 414 patients with probable PSP‐Richardson syndrome from 1994 to 2020. The data set comprised demographics and, for each visit, 28 PSP Rating Scale (PSPRS) items and PSP stage scores. We calculated the rate of progression of each PSPRS item as its item score when the downgaze item first reached 1 or more (on a 0–4 scale) divided by disease duration at that point. Multivariate Cox regression was applied to identify variables independently associated with survival. We also explored the progression pattern of total PSPRS and downgaze palsy scores with disease course.ResultsIndependently associated with shorter survival were older onset age and faster progression of downgaze palsy, dysphagia for liquids, difficulty in returning to seat, and PSP stage. Patients with survival duration within 1 year of the median survival (6.58 years) showed approximately linear progression of the PSPRS score and downgaze palsy score during years 2 through 6 of the disease course.ConclusionsOlder onset age and faster progression of downgaze palsy and several axial features are associated with shorter survival. The disease typically progresses in approximately linear fashion during years 2 through 6. These results may aid study design and patient counseling. © 2022 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Optical coherence tomography for dynamic investigation of mammalian reproductive processes
Authors: Umezu Kohei , Larina Irina V. 
Published: December 2022

AbstractThe biological events associated with mammalian reproductive processes are highly dynamic and tightly regulated by molecular, genetic, and biomechanical factors. Implementation of live imaging in reproductive research is vital for the advancement of our understanding of normal reproductive physiology and for improving the management of reproductive disorders. Optical coherence tomography (OCT) is emerging as a promising tool for dynamic volumetric imaging of various reproductive processes in mice and other animal models. In this review, we summarize recent studies employing OCT‐based approaches toward the investigation of reproductive processes in both, males and females. We describe how OCT can be applied to study structural features of the male reproductive system and sperm transport through the male reproductive tract. We review OCT applications for in vitro and dynamic in vivo imaging of the female reproductive system, staging and tracking of oocytes and embryos, and investigations of the oocyte/embryo transport through the oviduct. We describe how the functional OCT approach can be applied to the analysis of cilia dynamics within the male and female reproductive systems. We also discuss the areas of research, where OCT could find potential applications to progress our understanding of normal reproductive physiology and reproductive disorders.
A pilot study of MRI radiomics for high‐risk prostate cancer stratification in 1.5 T MR‐guided radiotherapy
Authors: Zhou Yihang , Yuan Jing , Xue Cindy , Poon Darren M. C. , Yang Bin , Yu Siu Ki , Cheung Kin Yin 
Published: December 2022

PurposeTo investigate the potential value of MRI radiomics obtained from a 1.5 T MRI‐guided linear accelerator (MR‐LINAC) for D'Amico high‐risk prostate cancer (PC) classification in MR‐guided radiotherapy (MRgRT).MethodsOne hundred seventy‐six consecutive PC patients underwent 1.5 T MRgRT treatment were retrospectively enrolled. Each patient received one or two pretreatment T2‐weighted MRI scans on a 1.5 T MR‐LINAC. The endpoint was to differentiate high‐risk from low/intermediate‐risk PC based on D'Amico criteria using MRI‐radiomics. Totally 1023 features were extracted from clinical target volume (CTV) and planning target volume (PTV). Intraclass correlation coefficient of scan–rescan repeatability, feature correlation, and recursive feature elimination were used for feature dimension reduction. Least absolute shrinkage and selection operator regression was employed for model construction. Receiver operating characteristic area under the curve (AUC) analysis was used for model performance assessment in both training and testing data.ResultsOne hundred and eleven patients fulfilled all criteria were finally included: 76 for training and 35 for testing. The constructed MRI‐radiomics models extracted from CTV and PTV achieved the AUC of 0.812 and 0.867 in the training data, without significant difference (P = 0.083). The model performances remained in the testing. The sensitivity, specificity, and accuracy were 85.71%, 64.29%, and 77.14% for the PTV‐based model; and 71.43%, 71.43%, and 71.43% for the CTV‐based model. The corresponding AUCs were 0.718 and 0.750 (P = 0.091) for CTV‐ and PTV‐based models.ConclusionMRI‐radiomics obtained from a 1.5 T MR‐LINAC showed promising results in D'Amico high‐risk PC stratification, potentially helpful for the future PC MRgRT. Prospective studies with larger sample sizes and external validation are warranted for further verification.
The osteoarthritis knowledge scale
Authors: Darlow Ben , Krägeloh Chris , Abbott J. Haxby , Bennell Kim , Briggs Andrew M. , Brown Melanie , Clark Jane , Dean Sarah , French Simon , Hinman Rana S. , Lawford Belinda J. , O’Brien Daniel , Whittaker Jackie L. , Stanley James 
Published: December 2022

AbstractObjectiveAccurate knowledge is central to effective self‐care of osteoarthritis (OA). This study aimed to assess the measurement properties of the Osteoarthritis Knowledge Scale (OAKS) with versions for the hip and knee.MethodsParticipants with hip OA (n = 144), knee OA (n = 327), and no OA (n = 735) were recruited. Rasch analysis was conducted to assess psychometric properties using data from all participants with hip OA and 144 randomly selected participants with either knee OA or no OA. Test‐retest reliability and measurement error were estimated among those with hip (n = 51) and knee (n = 142) OA.ResultsFour items from the draft scales were deleted following Rasch analysis. The final 11‐item OAKS was unidimensional. Item functioning was not affected by gender, age, educational level, or scale version (hip or knee). Person separation index was 0.75. Test‐retest intraclass correlation coefficient was 0.81 (95% CI 0.74, 0.86; hip version 0.66 [0.47, 0.79]; knee version 0.85 (0.79, 0.90)). Smallest detectable change was 9 points (scale range 11–55; hip OA version 11 points; knee OA version 8 points).ConclusionThe OAKS is a psychometrically adequate, unidimensional measure of important OA knowledge that can be used in populations with and without hip and knee OA. Caution is needed when using with populations with only hip OA as test‐retest reliability of the hip version did not surpass the acceptable range.
The RISE FOR HEALTH study: Methods for in‐person assessment and biospecimen collection
Authors: Brubaker Linda , Barthold Julia , Fitzgerald Colleen M. , Kenton Kimberly , Lewis Cora E. , Lowder Jerry , Lukacz Emily S. , Markland Alayne , Meister Melanie , Miller Janis , Mueller Elizabeth R. , Rudser Kyle , Smith Ariana L. , Newman Diane K. ,   The Prevention of Lower Urinary Tract Symptoms (PLUS) Research Consortium
Published: December 2022

AbstractObjectivesTo describe the methods for the in‐person assessment of the RISE FOR HEALTH (RISE) study, a population‐based multicenter prospective cohort study designed to identify factors that promote bladder health and/or prevent lower urinary tract symptoms in adult women, conducted by the Prevention of Lower Urinary Tract Symptoms Research Consortium (PLUS).Methods and resultsA subset of RISE participants who express interest in the in‐person assessment will be screened to ensure eligibility (planned n = 525). Eligible consenting participants are asked to complete 15 physical assessments in addition to height and weight, to assess pelvic floor muscle function, musculoskeletal (MSK) status, and pain, and to provide urogenital microbiome samples. Pelvic floor muscle assessments include presence of prolapse, strength, levator attachment integrity (tear) and myofascial pain. MSK tests evaluate core stability, lumbar spine, pelvic girdle and hip pain and function. Participants are asked to complete the Short Physical Performance Battery to measure balance, lower extremity strength, and functional capacity. All participants are asked to provide a voided urine sample and a vaginal swab for microbiome analyses; a subset of 100 are asked to contribute additional samples for feasibility and validation of a home collection of urinary, vaginal, and fecal biospecimens.ResultsOnline and in‐person training sessions were used to certify research staff at each clinical center before the start of RISE in‐person assessments. Standardized protocols and data collection methods are employed uniformly across sites.ConclusionsThe RISE in‐person assessment is an integral portion of the overall population‐based RISE study and represents an innovative approach to assessing factors hypothesized to promote bladder health and/or prevent lower urinary tract symptoms. Data collected from this assessment will be used to prioritize future research questions and prevention strategies and interventions. This description of the assessment methods is intended to provide methodologic transparency and inform other researchers who join efforts to understand and improve bladder health.
Exploring the relationship between lateral violence and nursing professionalism through the mediating effect of professional identity: A cross‐sectional questionnaire study
Authors: Xu Huiwen , Xue Mengxin , Takashi En , Kitayama Akio , Zhu Pingting , Liu Yongbing 
Published: December 2022

AbstractAimThis study aimed to investigate the prevalence of lateral violence (LV) experienced by nursing students during their internship, explore the difference between professional identity and professionalism among nursing students who had or had not experienced LV and analyse the mediating effect of professional identity on the relationship between LV and professionalism.DesignA cross‐sectional survey was used.MethodsAn online anonymous survey was distributed to nursing students (N = 298) in Jiangsu province, China from June to July 2021. The questionnaire consisted of sections on lateral violence, professional identity and nursing professionalism.ResultsApproximately 49.7% of the nursing students experienced LV behaviour during the internship period. Students who experienced LV had lower professional identity and professionalism than those who did not. Among the students, LV was negatively correlated with professional identity (r = −0.333, p < 0.001) and professionalism (r = −0.418, p < 0.001). The relationship effect of LV on nursing professionalism was partly mediated by professional identity.ConclusionNearly half of the nursing students suffered from LV in the workplace, and this condition remarkably influenced nursing professionalism through professional identity. Both quantitative and qualitative studies are needed to investigate the factors that influence LV development in detail.
Attention‐deficit hyperactivity symptoms and risk of alcohol use relapse
Authors: Kawata Takahiro , Sugihara Genichi , Kakibuchi Yoichi , Tomitaka Midori , Miyajima Miho , Matsushima Eisuke , Takeuchi Takashi , Takahashi Hidehiko 
Published: December 2022

AbstractAimAlcohol use disorder (AUD) is frequently accompanied by comorbid attention‐deficit hyperactivity disorder (ADHD). Comorbid ADHD has been reported to increase the severity of AUD. We investigated whether ADHD severity also influences AUD relapse risk at baseline and after inpatient treatment.MethodsIn this study, 187 AUD patients admitted to Narimasu Kosei Hospital from October 2019 to March 2021 were included in the analysis. According to the Adult ADHD Self‐Report Scale (ASRS), participants were divided into two groups: ASRS+ with ADHD characteristics (n = 43) and ASRS− with low/no ADHD characteristics (n = 144). Groups were compared for AUD relapse risk at the start of treatment (baseline) and before hospital discharge using the multidimensional Alcohol Relapse Risk Scale (ARRS). The change in relapse risk during hospitalization was also compared by assessment of the interaction between groups (ASRS+ vs. ASRS−) and time (at discharge vs. baseline).ResultsThe total ARRS score and dimension subscores for stimulus‐induced vulnerability and emotionality problems were significantly higher in the ASRS+ group at baseline and before discharge compared to the ASRS− group. There was a significant group × time interaction indicating less improvement of stimulus‐induced vulnerability during inpatient treatment among the ASRS+ group compared to the ASRS− group.ConclusionsOur findings suggest that AUD patients with ADHD characteristics have a higher risk of relapse both at baseline and after inpatient treatment. Stimulus‐induced vulnerability to relapse is less likely to improve with treatment in patients with ADHD characteristics.