bluuebunny/crossref_metadata_2025_split huggingface dataset:
Physical Versus Virtual Reality–Based Calm Rooms for Psychiatric Inpatients: Quasi-Randomized Trial
Authors: Ilioudi Maria , Lindner Philip , Ali Lilas , Wallström Sara , Thunström Almira Osmanovic , Ioannou Michael , Anving Nicole , Johansson Viktor , Hamilton William , Falk Örjan , Steingrimsson Steinn 
Published: March 2023

Background
Interest in sensory rooms or so-called “calm rooms” in psychiatric inpatient care has increased significantly. In a hospital setting, their purpose is to introduce a relaxing environment to increase well-being as well as to decrease anxiety and aggressive behaviors. Calm rooms can also be used as a tool to provide self-help through a convenient environment for the patients and, at the same time, strengthen the therapeutic relationship between the patient and the professional. Recent developments in virtual reality (VR) have made virtual calm rooms possible, but these have not yet been evaluated in psychiatric inpatient care.

Objective
This study aimed to compare the effects of VR and physical calm rooms on self-reported well-being and physiological markers of arousal.

Methods
The study was conducted in 2 inpatient psychiatric wards specializing in bipolar disorder from March 2019 to February 2021. Patients who were already admitted were asked if they were interested in using a calm room and willing to provide ratings. This study relied on the quasi-randomized allocation of patients to the wards, which either had a physical or VR calm room. Self-assessment scales (Montgomery-Åsberg Depression Rating Scale-Self Assessment [MADRS-S], Beck Anxiety Scale, and Clinical Global Impression) were used to determine the participants' baseline level of depressive and anxiety symptoms before their use of the physical or VR calm room. The study determined the state of well-being measured using an 11-point visual analog scale (VAS) as well as arousal measured by blood pressure (systolic and diastolic) and heart rate before and after the use of the calm rooms. The primary end point was self-reported well-being using the VAS.

Results
A total of 60 participants were included—40 used the VR calm room and 20 used the physical calm room. The mean age of participants was 39 years and the majority were women (35/60, 58%). Analysis of VAS measurement showed improved well-being at the group level from before to after the intervention (P<.05), with no statistically significant difference in effects between the 2 different interventions. Effects were not moderated by baseline depression levels (dichotomized as MADRS-S >20 or ≤20) despite an overall difference in reported well-being between subgroups.

Conclusions
Although the power in this study was low, the findings of this first study indicate comparable effects with respect to well-being and arousal of a VR calm room and a physical calm room. This suggests that a VR calm room can be a viable alternative when the use of a physical calm room is not an option for logistic or other reasons.

Trial Registration
ClinicalTrials.gov NCT03918954; https://clinicaltrials.gov/ct2/show/NCT03918954
THE DEVELOPMENT AND STUDY OF THE TOXICITY OF SUPPOSITORIES WITH A MODIFIED SUBSTANCE OF INTERFERON ALFA-2B
Authors: ANUROVA MARIA N. , BAKHRUSHINA ELENA O. , SHUMKOVA MARINA M. , DEMINA NATALIA B. , KRASNYUK IVAN I. 
Published: March 2023

Objective: To develop a stable composition with the substance of PEGylated interferon alfa-2b, to study technological and biopharmaceutical characteristics of the dosage form, and to conduct preclinical studies on the chronic toxicity and local irritating effect.
Methods: Solid fats Witepsol® H15, Witepsol® W 35, Suppocire® BS2X, and Suppocire® BM brands were used as the suppository bases. Polysorbate 80 was used as an emulsifier. Citric acid, ascorbic acid, sodium tetraborate, lactic acid, ethylenediaminetetetraacetic acid, tocopherol acetate was also introduced into the experimental samples. Fourteen experimental samples were screened for biological and technological indicators. Preclinical studies were performed for the optimal composition on the indicators of chronic toxicity and local irritant effect.
Results: The study examined the cytotoxic effects on the Vero cell line of selected suppository bases and excipients, namely, pH regulators and antioxidants. With excipients that did not have cytotoxicity we obtained suppository compositions with the following quality indicators: cytotoxicity, specific activity of interferon, time of complete deformation of suppositories and their melting temperature. A total of 14 compositions were studied, of which 5 were selected on the basis of the results for the study of stability. Only one composition turned out to be stable for the time studied.
Conclusion: The most stable in terms of “specific activity” was sample 7, its composition: Witepsol® H15/W35 70/30, polysorbate-80 0.15%, ethylenediaminetetraacetic acid (EDTA) 0.15%, sodium tetraborate 0.15%, tocopherol acetate 3.0%. Preclinical studies, that showed the absence of chronic toxicity and local irritant effect, were performed for this composition.
Lev Tikhomirov: overcoming the revolution and criticizing democracy
Authors: Smolin M. B. 
Published: March 2023

The French Revolution, having raised the idea of “the people’s will” to its banners, for several centuries determined human society itself as the center of the application of human efforts. The European peoples, brought up in Christian idealism, with its absolute moral requirements, were reoriented to the social world, with its extremely limited possibilities for retribution of justice.L.A. Tikhomirov systematically revised the views on democracy that had developed in European political philosophy. His thinking surprisingly combined both a critical perception of other people’s conclusions and the ability to build his own positive constructions. He could both introduce doubts into seemingly well-established postulates, and convince of the correctness of his positive political constructions.Considering revolutionary ideas to be largely artificially introduced, L.A. Tikhomirov, argued that their influence in Russia is largely due to the “lack of Russian national intelligentsia”. The extreme lack of independence of the social sciences in Russia, unable to study their national political experience and give recommendations on the development of the country for the future. In his understanding of the evolution of social experiences, L.A. Tikhomirov, blamed the “new era” opened by the French Revolution of the 18th century for their futility. It is from her that he sees the violation of the spiritual balance that has put people on the path of fruitless chimeras.Assuming that the hypertrophied individualism of liberalism, as a reaction to it, could be replaced by socialism with its all-consuming collectivism, L.A. Tikhomirov recognized this possibility only through revolutionary upheavals. He saw such a radical upheaval as useless and dangerous, due to the fact that in his criticism of democracy the main point was his denial of the possibility of building a society in which the Supreme Power can really and directly be the people’s will.
La interpretación en el ámbito sanitario en un destino turístico y de inmigración irregular en España: los efectos de la pandemia acentúan las carencias del servicio
Authors: Pérez-Luzardo Díaz Jessica , Santana García Mónica del Carmen 
Published: March 2023

Este estudio pretende averiguar cómo ha afectado la COVID-19 a la comunicación entre el personal hospitalario y los pacientes extranjeros en los centros sanitarios públicos de Gran Canaria, un destino turístico y de inmigración irregular. Tras contextualizar la situación de la COVID-19 en España, abordamos la situación de la interpretación en Canarias. Se explica un estudio descriptivo realizado mediante cuestionarios al personal de los dos hospitales públicos de la isla de Gran Canaria. Tras analizar los resultados obtenidos, se hace visible el problema de comunicación existente debido a la falta de un servicio de interpretación sanitario. La mayoría del personal manifiesta tener problemas de comunicación y el cincuenta por ciento considera que durante la pandemia los problemas de comunicación son mayores. No obstante, se pone de manifiesto un problema que trasciende el contexto pandémico.
De la novela al cine y a la ficción televisiva
Authors: Rosales García Cristina 
Published: March 2023

El presente volumen es un compendio de cinco artículos en los que se trabajan los conceptos de adaptación múltiple y reescritura, es decir, cuando una obra literaria es llevada a la gran y a la pequeña pantalla en más de una ocasión. Así pues, a lo largo de estos artículos se establece un diálogo entre el hipotexto y los diferentes hipertextos que enriquece la relación entre el medio literario y el audiovisual. En primer lugar se ofrece un estado de la cuestión y dos corpus selectivos para dar paso al análisis de las diferentes adaptaciones de novelas como Mujercitas de Louisa May Alcott, Nada de Carmen Laforet, La ciudad y los perros de Mario Vargas Llosa y los trasvases televisivos del comisario Montalbano, el célebre personaje de Andrea Camilleri. Gracias a las múltiples miradas y perspectivas que aquí se presentan se abren nuevas vías de investigación dentro del ámbito de la adaptación.
Patterns of Cooperation in the European Defence Sector – A Network-Approach-Based Investigation of EU Projects
Authors: Balogh Péter 
Published: March 2023

Abstract
In this paper, we introduce research results from our network-approach-based investigation of the European Union defence cooperation projects. After brief remarks on the background, the research problem, the conceptual and methodological issues, we focus on the structure of the cooperation network and introduce the territorial, institutional, and (sub)regional patterns of partnerships. The data analyses illustrate that an integrated but fragmented cooperation network could be explored, and in several aspects remarkable differences can be measured on country-, regional, and sub-regional levels implying that territorial and institutional factors might have an important role in this specific area as well.
Exploitation of Narrow-Gauge Railways for Tourism in the South Transdanubian Region
Authors: Pavletits Peter 
Published: March 2023

Abstract
Since the 1980s, almost all of the Hungarian narrow-gauge railway lines underwent a complete change of function. About 120-140 years ago, narrow-gauge railways were created mainly for economic purposes. Nowadays, with a few exceptions, freight operation is completely eliminated and replaced by tourism. In my study, I deal with two questions: on the one hand, I will examine the place of the existing narrow-gauge railways in the tourism system. In this context, I will present the tourism potential of narrow-gauge railways. These include, for example, the availability of narrow-gauge railways, their inclusion in the wider tourism system, the material conditions of the basic infrastructure of narrow-gauge railways, etc. On the other hand, by presenting four railway lines from South Transdanubia, I will examine how well the opportunities offered by tourism have been exploited at the local level, what the impact of narrow-gauge railways is on tourism, and what the tourism-related significance of these lines is at all. Based on my analysis, it can be concluded that the narrow-gauge railway sector is developing within the tourism system, and compared to the period before the COVID-19 pandemic (2020–2021), investments, technical developments, and attendance have also increased. It is also clear from the South Transdanubian cases that the narrow-gauge railway system is becoming more and more important especially where it can be connected to other tourist attractions (natural parks, forest schools, etc. ), which is also evident in the attendance indicators.
Knowledge and attitude of young female population toward early diagnosis of polycystic ovary syndrome
Authors: Naz Saima , Asghar Farhana , Iqbal Yusra , Naseem Zulekha , jathol Mahnoor 
Published: March 2023

<p>Background and Objective: The heterogeneous illness known as polycystic ovary syndrome (PCOS) causes multisystem morbidities and is one of the major causes of female infertility. This study aimed at assessing the knowledge and attitude of the young female population towards the early diagnosis of PCOS in Pakistan.</p>
<p>Methods: This cross-sectional questionnaire-based survey study was carried out at the Lahore Wapda Hospital Complex, Pakistan over a period of 1 year (January 2021 to 2022). A total of 1,278 females with active PCOS from 18-23 years of age were selected for the study from all provinces of Pakistan. A total of 96 responses were excluded because of inconsistency, incompletion, or duplication while the remaining 1,182 respondents were finally included in the study. Regression analysis, analysis of variance, and t-test were applied for statistical inferences.</p>
<p>Results: Only 45.3% of the patients had significant knowledge (p-value = 0.001) or a positive attitude about the early diagnosis of PCOS. The participants who were diagnosed with abdominal ultrasonography scored significantly higher in attitude towards earlier diagnosis than those who were diagnosed with serum gonadotropins and/or androgens levels (p = 0.001).</p>
<p>Conclusion: Lack of appropriate information and awareness regarding PCOS and its complications while bearing a poor attitude concerning the early diagnosis of this syndrome leads to higher disease burden and morbidity in our younger female population.</p>
MENGGALI POTENSI DIRI DAN MOTIVASI INTRINSIK UNTUK MEMBENTUK MINAT BERWIRAUSAHA
Authors: Amran Ellyana , Syofyan Syofriza , Tanuwijaya Justine , Zahra Parinduri Aina 
Published: March 2023

Peran wirausaha dalam perekonomian merupakan penggerak ekonomi yang penting dengan menumbuhkan jiwa wirausaha, yang dapat dipercaya sebagai solusi keterbatasan kesempatan kerja dan pengentasan kemiskinan. Menggali potensi diri dan motivasi intrinsk menjadi perhatian santri, karena sudah saatnya santri menentukan keberhasilannya sebagai pendakwah yang mempunyai kemampuan berwirausaha. Metode yang digunakan adalah metode partsipatif, yang dianalisis secara deskriptif kualitatif. Hasil penelitian menunjukkan bahwa secara umum peserta memiliki minat berwirausaha yang cukup tinggi, karena sudah dibentuk melalui ketrampilan, pengalaman serta budaya kewirauashaan dalam kegiatan di pondok pesantren. Akan tetapi masih belum optimal dalam menggali potensi diri serta pemahaman terkait pengetahuan kewirausahaan yang masih rendah.
Dampak Sosialisasi Pengolahan Limbah Cangkang Kelapa Sawit Sebagai Bahan Bakar Alternatif di Kelurahan Sidomukti, Kisaran Barat
Authors: Dalimunthe Yusraida Khairani , Satiawati Listiana , Wijayanti Puri , Wijaya Budi 
Published: March 2023

Telah terlaksana Pengabdian Kepada Masyarakat (PKM) dengan tema sosialisasi limbah dari cangkang kelapa sawit yang dijadikan sebagai bahan bakar alternatif di Kelurahan Sidomukti, Kisaran Barat. Adapun tujuan dilakukannya kegiatan PKM ini yakni agar pengetahuan dari warga masyarakat di Kelurahan Sidomukti mengenai energi terbarukan salah satunya yakni biomass dari limbah cangkang kelapa sawit menjadi meningkat. Kegiatan PKM ini sendiri terlaksana pada tanggal 15 Januari 2022 yang bertempat di kediaman ketua pelaksana dan diikuti oleh warga setempat. Penyebaran angket pra sosialisasi dilakukan di awal dimana guna dari angket ini yakni untuk melihat bagaimana tingkat pengetahuan warga terkait energi terbarukan sebelum sosialisasi dilaksanakan. Selanjutnya dilaksanakan pemaparan kepada warga mengenai apa itu energi terbarukan, briket serta cara pembuatannya dari limbah cangkang kelapa sawit, kegunaannya hingga nilai ekonominya melalui presentasi dan juga video. Diakhir kegiatan dilakukan kembali pemberian angket guna mengevaluasi sejauh mana peningkatan pengetahuan warga setelah diadakannya sosialisasi. Dari hasil penelitian didapatkan bahwa 100% masyarakat merasakan manfaat dari peningkatan pengetahuan mereka terkait briket dari limbah cangkang kelapa sawit dan 20 dari 29 responden yang menyatakan keinginannya untuk menerapkan briket ini sebagai pengganti bahan bakar rumah tangga atau bahan bakar di industri makanan dan industri manufaktur lainnya ketika mereka memiliki bisnis terkait di masa depan.
SOSIALISASI JARINGAN GAS PERKOTAAN BAGI MASYARAKAT
Authors: Ristawati Arinda , Prima Andry , Yulia Prayang Sunny , Kurniawati Riskaviana , Puspitosari Meldinar Riska , Fattahanisa Aqlyna , Wijayanti Puri , Aryanto Reza 
Published: March 2023

Sosialisasi Gas Perkotaan merupakan PKM yang memiliki tujuan agar masyarakat dapat Memahami tentang pertumbuhan pada sektor distribusi gas kota di Indonesia dan Memberikan Informasi kepada masyarakat tentang Sumber Energi yang Ekonomis untuk Menggantikan LPG. Jaringan gas untuk rumah tangga yaitu dialirkannya gas melalui jaringan – jaringan pipa yang terpasang sehingga dapat didistribusikan ke rumah tangga. Masih terbatasnya ketersediaan jargas rumah tangga di DKI Jakarta, yang membuat tema sosialisasi ini diangkat, Metode yang dilakukan yaitu memberikan sosialisasi mengenai jaringan gas perkotaan yang dikembangkan pemerintah untuk keperluan gas rumah tangga, sosialisasi di lakukan melalui online dengan fasilitas zoom dan Sebagian lainnya secara ofline di masyarakat dengan tetap mengenakan prokes yang ada. Hasil Kegiatan PKM ini masyarakat mampu mengenal dan memahami keberadaan jargas yang pengembangan infrastrukturnya sedang diperluas oleh pemerintah melalui PT PGN Tbk. Dalam sosialisasi juga dibahas mengenai manfaat, satunya Penyerapan Tenaga Kerja, Mendukung Pertumbuhan Ekonomi Mengurangi Impor LPG Mendukung Pertumbuhan Ekonomi Mengurangi Impor LPG. Keunggulan yang menarik dari penggunaan Jargas yaitu penyaluran gas menggunakan pipa sehingga dapat optimal dari sisi ruang, pengukuran yang akurat dan system pembayaran pasca bayar, pasokan gas terjaga tanpa risiko kehabisan gas, dan memiliki fitur keamanan yang lebih terjamin. PKM ini membuat masyarakat mengetahui secara jelas alur dalam program pengembangan jargas.
HUBUNGAN INDEKS MASSA TUBUH DENGAN KADAR HBA1C PADA PENDERITA DIABETES MELITUS TIPE-2
Authors: Adriani Donna , Hurin Salsabila , Amani Patwa 
Published: March 2023

BACKGROUND
Diabetes mellitus (DM) is a state of increased sugar levels in the blood vessels. DM can interfere with organ function and cause death. One of the criteria for diagnosing DM based on ADA is HbA1c. In 2019, 463 million people with DM aged 20 to 79 years worldwide. DM sufferers are estimated to increase every year due to risk factors: race, age, gender, lack of physical activity, unhealthy and unbalanced diet, overweight or obesity. Overweight or obesity is detected by calculating the Body Mass Index. The purpose of this study was to determine the relationship between body mass index and HbA1c levels in patients with type-2 diabetes mellitus.

METHODS
Observational analytic study with cross-sectional design. The total sample is 90 respondents obtained from medical record data at RSUD dr. Soekardjo Tasikmalaya City in type-2 DM patients. Data analysis was performed using Fisher's exact test on the SPSS version 25 program.

RESULTS
Characteristics of respondents who are >45 years old (82.2%) and female (71.1%). There was no significant relationship between age and HbA1c (p-value = 0.633). There was no significant relationship between BMI and HbA1c (p-value = 0.011).

CONCLUSIONS
In this study, there was no significant relationship between body mass index and HbA1c levels in patients with type-2 diabetes mellitus. BMI should be considered when using the HbA1c assay to diagnose and manage type-2 diabetes.
PREDIKTOR KETIDAKHADIRAN IBU PADA KUNJUNGAN NIFAS SELAMA PANDEMI COVID-19
Authors: Sinaga Evi Susanti , Luthfi Aziz  , Pierre Christoper H  , Zulfa Febri Sofyani  , Kartika Putri Pertiwi  , Rina K. Kusumaratna  
Published: March 2023

Kematian ibu merupakan ukuran yang digunakan salah satunya dalam menilai tingkat kesehatan dan keberhasilan pembangunan kesehatan. Kematian ibu, berdasarkan Organisasi Kesehatan Dunia, merupakan kematian yang terjadi selama masa kehamilan, persalinan, dan nifas disebabkan karena kehamilan, persalinan, dan nifas ataupun pengelolaannya tetapi bukan disebabkan hal lain seperti kecelakaan. Salah satu upaya pencegahan kematian ibu adalah melalui pelayanan masa nifas. Cakupan kunjungan nifas di Kelurahan Bukit Duri belum mencapai target (80,26%) selama pandemi Covid-19. Penelitian ini bertujuan menganalisis faktor yang berhubungan dengan kepatuhan kunjungan ibu nifas di Puskesmas Bukit Duri pada saat pandemi Covid-19. Desain penelitian ini menggunakan desain cross sectional. Teknik pengambilan sampel menggunakan total population sampling yaitu seluruh ibu nifas di kelurahan Bukit Duri yang tercatat pada bulan November 2021 menjadi sampel yaitu sebanyak 49 orang. Analisis data dilakukan secara bivariat dengan menggunakan uji statistik chi square. Faktor-faktor yang berhubungan dengan kepatuhan kunjungan nifas adalah dukungan keluarga (p-value= 0,000), kepercayaan terhadap mitos (p-value= 0,003), dan pandemi Covid-19 (p-value= 0,006). Sedangkan tingkat pendidikan, usia, status ibu bekerja, dan jumlah paritas tidak berhubungan secara statistik dengan kepatuhan kunjungan nifas (p-value > 0,05).
ANALISIS FAKTOR-FAKTOR DALAM PILIHAN BERKARIR SEBAGAI AKUNTAN PUBLIK BAGI MAHASISWA AKUNTANSI UNIVERSITAS TANJUNGPURA PONTIANAK
Authors: Rachmadiyanti Risdiandini , Pratiwi Anggita Dwi , Ramadini Puput Artha , Puspitasari Ayu , Yunita Khristina 
Published: March 2023

Perkembangan dunia kerja yang sangat pesat memiliki dampak yang positif namun juga menjadi tantangan bagi semua orang. Tak terkecuali bagi mahasiswa yang mempersiapkan diri untuk terjun dalam dunia kerja. Perkembangan profesi akuntan publik di Indonesia berbanding terbalik dengan kebutuhannya yang semakin banyak. Berdasarkan Institut Akuntan Publik Indonesia (IAPI) terdapat 6.208 anggota Akuntan Publik (KAP) yang aktif, dan terdapat 464 Kantor Akuntan Publik (KAP) dengan izin dari Kementerian Keuangan per 3 Oktober 2022. Data tersebut menunjukkan kurangnya minat dalam profesi Akuntan Publik, yang dipengaruhi oleh faktor orangtua, motivasi, dan gender.Penelitian bertujuan menganalisa faktor-faktor dalam pilihan berkarir sebagai akuntan publik bagi mahasiswa akuntansi Universitas Tanjungpura. Variabel yang diuji dalam penelitian adalah orang tua, gender, dan motivasi. Data menggunakan data primer dengan penyebaran kuesioner. Populasi penelitian mahasiswa jurusan akuntansi angkatan 2019. Pemilihan sampel menggunakan teknik purposive sampling dan sampel 61 responden. Teknik analisis menggunakan regresi linear berganda dibantu software SPSS 23. Hasil menunjukkan variabel orang tua berpengaruh signifikan terhadap pilihan berkarir sebagai akuntan publik dan variabel motivasi berpengaruh signifikan terhadap pilihan berkarir sebagai akuntan publik. Sedangkan variabel gender tidak berpengaruh signifikan terhadap pilihan berkarir sebagai akuntan publik.Kata kunci: Orang Tua, Gender, Motivasi, Pilihan Berkarir Sebagai Akuntan Publik.