bluuebunny/crossref_metadata_2025_split huggingface dataset:
Refinement of Spatio-Temporal Finite Element Spaces for Mean Sea Surface and Sea Level Anomaly Estimation
Authors: Borlinghaus Moritz , Neyers Christian , Brockmann Jan Martin 
Published: July 2023

AbstractThe mean sea surface (MSS) is an important reference surface for oceanographic or geodetic applications such as sea level studies or the geodetic determination of the steady-state ocean circulation. Models of the MSS are derived from averaged along-track radar altimetry which provides instantaneous measurements of the sea surface heights (SSH). SSH observations corrected for tides and other physical signals and can be modeled as the sum of the MSS and sea level anomalies (SLA) which describe the temporal variability of the ocean. The typical MSS products are defined as grids of heights at a specific reference epoch and result from spatial and temporal prediction and filtering of the along-track SSH observations, whereas SLA products are computed with respect to an MSS model and are also defined as e.g. daily or averaged monthly grids.In this contribution a one-step least-squares approach is used to estimate a continuous spatio-temporal model of the MSS and filtered SLAs from along-track altimetric SSH measurements using
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-smooth finite element spaces for the spatial representation. The finite elements are defined on triangulations with different edge lengths and, thus, different spatial resolutions for MSS and SLA modeling. To model the temporal ocean variability finite B-Splines base functions are combined with the spatial finite elements to construct a spatio-temporal model. This contribution presents a concept to adapt the triangulations to the spatial characteristics of the signal of the MSS and SLA in a study region south of Africa. Least-squares residuals are studied to detect areas which show unmodeled spatial signal. These serve as input for the refinement of the triangulation. The results show that the residuals are indeed a good indicator for unmodeled signal, but as they are significantly influenced by unmodeled temporal signals as well, the refinement has only a small local impact on the obtained MSS and SLA models.
Dual-attention Network for View-invariant Action Recognition
Authors: Kumie Gedamu Alemu , Habtie Maregu Assefa , Ayall Tewodros Alemu , Zhou Changjun , Liu Huawen , Seid Abegaz Mohammed , Erbad Aiman 
Published: July 2023

AbstractView-invariant action recognition has been widely researched in various applications, such as visual surveillance and human–robot interaction. However, view-invariant human action recognition is challenging due to the action occlusions and information loss caused by view changes. Modeling spatiotemporal dynamics of body joints and minimizing representation discrepancy between different views could be a valuable solution for view-invariant human action recognition. Therefore, we propose a Dual-Attention Network (DANet) aims to learn robust video representation for view-invariant action recognition. The DANet is composed of relation-aware spatiotemporal self-attention and spatiotemporal cross-attention modules. The relation-aware spatiotemporal self-attention module learns representative and discriminative action features. This module captures local and global long-range dependencies, as well as pairwise relations among human body parts and joints in the spatial and temporal domains. The cross-attention module learns view-invariant attention maps and generates discriminative features for semantic representations of actions in different views. We exhaustively evaluate our proposed approach on the NTU-60, NTU-120, and UESTC large-scale challenging datasets with multi-type evaluation metrics including Cross-Subject, Cross-View, Cross-Set, and Arbitrary-view. The experimental results demonstrate that our proposed approach significantly outperforms state-of-the-art approaches in view-invariant action recognition.
Graph-based feature extraction on object-centric event logs
Authors: Berti Alessandro , Herforth Johannes , Qafari Mahnaz Sadat , van der Aalst Wil M. P. 
Published: July 2023

AbstractProcess mining techniques have proven crucial in identifying performance and compliance issues. Traditional process mining, however, is primarily case-centric and does not fully capture the complexity of real-life information systems, leading to a growing interest in object-centric process mining. This paper presents a novel graph-based approach for feature extraction from object-centric event logs. In contrast to established methods for feature extraction from traditional event logs, object-centric logs present a greater challenge due to the interconnected nature of events related to multiple objects. This paper addresses this gap by proposing techniques and tools for feature extraction specifically designed for object-centric event logs. In this work, we focus on features pertaining to the lifecycle of the objects and their interaction. These features enable a more comprehensive understanding of the process and its inherent complexities. We demonstrate the applicability of our approach through its implementation in two significant areas: anomaly detection and throughput time prediction for objects in the process. Our results, based on four problems in a Procure-to-Pay process, affirm the potential of our proposed features in enhancing the scope of process mining. By effectively transforming object-centric event logs into numeric vectors, we pave the way for the application of a broader range of machine learning techniques, such as classification, prediction, clustering, and anomaly detection, thereby extending the capabilities of process mining.
Subjective and objective sleep alterations in medication-naïve children and adolescents with autism spectrum disorder: a systematic review and meta-analysis
Authors: Kim Heeyeon , Kim Jae Han , Kim Junghwan , Kim Jong Yeob , Cortese Samuele , Smith Lee , Koyanagi Ai , Radua Joaquim , Fusar-Poli Paolo , Carvalho Andre F. , Salazar de Pablo Gonzalo , Shin Jae Il , Cheon Keun-Ah , Solmi Marco 
Published: July 2023

Abstract

Aims
This study aimed to summarize the evidence on sleep alterations in medication-naïve children and adolescents with autism spectrum disorder (ASD).

Methods
We systematically searched PubMed/Medline, Embase and Web of Science databases from inception through March 22, 2021. This study was registered with PROSPERO (CRD42021243881). Any observational study was included that enrolled medication-naïve children and adolescents with ASD and compared objective (actigraphy and polysomnography) or subjective sleep parameters with typically developing (TD) counterparts. We extracted relevant data such as the study design and outcome measures. The methodological quality was assessed through the Newcastle-Ottawa Scale (NOS). A meta-analysis was carried out using the random-effects model by pooling effect sizes as Hedges’ g. To assess publication bias, Egger’s test and p-curve analysis were done. A priori planned meta-regression and subgroup analysis were also performed to identify potential moderators.

Results
Out of 4277 retrieved references, 16 studies were eligible with 981 ASD patients and 1220 TD individuals. The analysis of objective measures showed that medication-naïve ASD patients had significantly longer sleep latency (Hedges’ g 0.59; 95% confidence interval [95% CI] 0.26 to 0.92), reduced sleep efficiency (Hedges’ g −0.58; 95% CI −0.87 to −0.28), time in bed (Hedges’ g −0.64; 95% CI −1.02 to −0.26) and total sleep time (Hedges’ g −0.64; 95% CI −1.01 to −0.27). The analysis of subjective measures showed that they had more problems in daytime sleepiness (Hedges’ g 0.48; 95% CI 0.26 to 0.71), sleep latency (Hedges’ g 1.15; 95% CI 0.72 to 1.58), initiating and maintaining sleep (Hedges’ g 0.86; 95% CI 0.39 to 1.33) and sleep hyperhidrosis (Hedges’ g 0.48; 95% CI 0.29 to 0.66). Potential publication bias was detected for sleep latency, sleep period time and total sleep time measured by polysomnography. Some sleep alterations were moderated by age, sex and concurrent intellectual disability. The median NOS score was 8 (interquartile range 7.25–8.75).

Conclusion
We found that medication-naïve children and adolescents with ASD presented significantly more subjective and objective sleep alterations compared to TD and identified possible moderators of these differences. Future research requires an analysis of how these sleep alterations are linked to core symptom severity and comorbid behavioural problems, which would provide an integrated therapeutic intervention for ASD. However, our results should be interpreted in light of the potential publication bias.
On the Dynamics of Water Transportation and Magmatism in the Mid‐Mantle
Authors: Yang Jianfeng , Faccenda Manuele 
Published: July 2023

AbstractThe distribution of water within the Earth's mantle has significant implications for the Earth's dynamics and evolution. Recent mineral physics experiments indicate that dense hydrous magnesium silicates can contain large amounts of water stable up to 60 GPa or even beyond along slab geotherms. Here we perform petrological‐thermomechanical numerical simulations of water transportation by deep slab subduction and related magmatism in the mid‐mantle. Key parameters including those defining the slab thermal parameter and the water storage capacity in the oceanic lithosphere and surrounding mantle are explored. The results show two major dehydration events of ultramafic rocks at around 150 and 750 km by dehydration of serpentine at 600°C and superhydrous phase B in the entrained wet upper mantle, respectively. Large amounts of water, ∼1.5 wt% at least locally, are carried down to the mantle transition zone and lower mantle. We estimate an upper limit of slab water flux into the mid‐mantle of 0.1–0.28 × 1012 kg/yr, which is ∼13%–37% of the input water from the serpentinized mantle. Moreover, a substantial fraction of the water released by the slab is absorbed by the entrained mantle and overlying mid‐mantle portions, such that ∼30%–70% of the water injected at the trench could be delivered to the lower mantle. The deepest magmatism is observed at ∼1,500 km in case of phase H breakdown (MgO‐SiO2‐H2O system), coinciding with the depth of strong seismic attenuation. Overall, these simulations suggest that up to 0.2 ocean mass per billion years could be transported down to the mid‐mantle and beyond.
circRNF13, a novel N6-methyladenosine-modified circular RNA, enhances radioresistance in cervical cancer by increasing CXCL1 mRNA stability
Authors: Shi Junyu , Rui Xiaohui , Han Chunxiao , Wang Chaoping , Xu Lei , Jiang Xiping 
Published: July 2023

Abstract
Background
Circular RNAs (circRNAs) and N6-methyladenosine (m6A) have been shown to play an increasingly critical role in the development of different cancers. However, there is limited evidence on how circRNAs and m6A interact to affect the radiosensitivity of cervical cancer (CC). This study provides a mechanistic understanding of the novel m6A-regulated circRNF13 in enhancing radioresistance in CC.

Methods
Differentially expressed circRNAs were identified from radiosensitive and radioresistant CC tissues. Meanwhile, these circRNAs were subjected to methylated RNA immunoprecipitation (Me-RIP). Finally, the effects of these circRNAs on radiosensitivity were characterized.

Results
CircRNF13 was poorly expressed in CC patients that were sensitive to concurrent radiochemotherapy. Experiments conducted both in vitro and in vivo confirmed that the knockdown of circRNF13 potentiated the radiosensitivity of CC cells. Further mechanistic studies revealed that METTL3/YTHDF2 promoted the degradation of circRNF13 and subsequently affected the stability of CXC motif chemokine ligand 1 (CXCL1), ultimately enhancing the radiosensitivity of CC cells.

Conclusion
This study identified circRNF13 as a novel m6A-modified circRNA and validated the METTL3/YTHDF2/circRNF13/CXCL1 axis as a potential target for CC radiotherapy.
Eye-brain axis in microgravity and its implications for Spaceflight Associated Neuro-ocular Syndrome
Authors: Stern Claudia , Yücel Yeni H. , zu Eulenburg Peter , Pavy-Le Traon Anne , Petersen Lonnie Grove 
Published: July 2023

AbstractLong-duration human spaceflight can lead to changes in both the eye and the brain, which have been referred to as Spaceflight Associated Neuro-ocular Syndrome (SANS). These changes may manifest as a constellation of symptoms, which can include optic disc edema, optic nerve sheath distension, choroidal folds, globe flattening, hyperopic shift, and cotton wool spots. Although the underpinning mechanisms for SANS are not yet known, contributors may include intracranial interstitial fluid accumulation following microgravity induced headward fluid shift. Development and validation of SANS countermeasures contribute to our understanding of etiology and accelerate new technology including exercise modalities, Lower Body Negative Pressure suits, venous thigh cuffs, and Impedance Threshold Devices. However, significant knowledge gaps remain including biomarkers, a full set of countermeasures and/or treatment regimes, and finally reliable ground based analogs to accelerate the research. This review from the European Space Agency SANS expert group summarizes past research and current knowledge on SANS, potential countermeasures, and key knowledge gaps, to further our understanding, prevention, and treatment of SANS both during human spaceflight and future extraterrestrial surface exploration.
Kirigami fog nets: how strips improve water collection
Authors: Bintein Pierre-Brice , Cornu Axel , Weyer Floriane , De Coster Nicolas , Vandewalle Nicolas , Terwagne Denis 
Published: July 2023

AbstractAs scarcity of water is expected to intensify with global warming, unconventional water sources such as advective fogs may become essential. In numerous arid regions, nets are used to harvest such water droplets. However, many current fog nets are either not durable or expensive, and have poor performances for short time or low intensity fog events. With a dedicated test bench, we show here that a low-cost net with kirigami design offers a higher and faster fog collecting ability than the usual fibers nets. This kirigami fog net consists of a continuous network of strips where water quickly forms a stable film, accounting for its superior capture efficiency. We rationalize this mechanism with a simplified structure composed of disconnected strips whose optimization paves the way to the shaping of original fog nets such as the kirigami one.
Screening for chitin degrading bacteria in the environment of Saudi Arabia and characterization of the most potent chitinase from Streptomyces variabilis Am1
Authors: Kotb Essam , Alabdalall Amira H. , Alghamdi Azzah I. , Ababutain Ibtisam M. , Aldakeel Sumayh A. , Al-Zuwaid Safa K. , Algarudi Batool M. , Algarudi Sakina M. , Ahmed Asmaa A. , Albarrag Ahmed M. 
Published: July 2023

AbstractForty-six promising chitinolytic isolates were recovered during a screening for chitinolytic bacteria in the environment of Saudi Arabia. The top three isolates belonged to the genus Streptomyces. Streptomyces variabilis Am1 was able to excrete the highest amount of chitinases, reaching the maximum at 84 h with 0.5% yeast extract and nitrogen source and 2% galactose as a carbon source. Purification of chitinase by DEAE-Cellulose and Sephadex G75 improved the specific activity to 18.6-fold and the recovery to 23.8% and showed a mass at 56 kDa. The optimal catalysis of the purified chitinase was at 40 °C and pH 8 with high thermostability and pH stability as reflected by a midpoint temperature value of 66.6 °C and stability at pH 4–9. The protein reagents SDS, EDTA, and EGTA significantly inhibited the enzyme and the EDTA-chelated chitinase restored its activity after the addition of Fe2+ ions suggesting a metallo-chitinase type with ferric ions as cofactors. Chitinase exerted high antifungal activity against some phytopathogenic fungi. Interestingly, the tested Streptomyces were able to produce chitosan nanocubes along with chitosan from chitin degradation which may be an additional power in their antifungal activity in nature. This work also reveals the importance of unexplored environments as a pool of promising microorganisms with biotechnological applications.
A study on the effect of radiographic angles on clubfoot’s recurrence
Authors: Tahririan Mohammad Ali , Kheiri Sara , Jannesari Ladani Mohammadreza , Piri Ardakani Mohammadreza 
Published: July 2023

AbstractClubfoot is one of the common orthopaedic deformities. However, regardless of its’ treatment high success rate, recurrence of the deformity is a serious issue. The aim of this study is to evaluate if radiographic angles can be used for clubfoot recurrence prediction. This is a prospective study on 91 patients (134 feet) with mean age of 9.5 ± 2.3 days and male/female ratio of 2/1 on patients with congenital clubfoot admitted to our hospital. Pre and one-year post-tenotomy tibiocalcaneal (TIC-L), talocalcaneal (TC-L) and calcaneal-first metatarsal angles (C1M-L) in the lateral view of the patients' radiographs, and their recurrence status until three years were measured. Ten feet experienced relapse. The mean pre and one-year follow-up measurements of TC-L, C1M-L, and TIC-L angles were significantly different between patients who experienced relapse and others (P < .05). The cut-off points of 1.75 and 6.5 for one-year follow-up Pirani and Dimeglio scores for recurrence prediction were suggested respectively. Also, cut-off points of 26.5 and 79.5 for one-year follow-up TC-L and TIC-L angles for recurrence prediction were calculated, respectively. We demonstrated that the pre-tenotomy and one-year follow-up TIC-L, TC-L, and C1M-L angles are helpful in clubfoot recurrence prediction after Ponseti treatment.
Hemorrhage from Adrenal Vein Rupture during Adrenal Vein Sampling
Authors: Quencer Keith B. , Massouh Alan , Anand Keshav 
Published: July 2023

AbstractWe describe a case of right adrenal hemorrhage from adrenal vein sampling treated conservatively with overnight admission and pain control. We review the existing literature on rates of this complication, typical clinical outcomes, and practical tips to avoid its occurrence.
Corruption, anti-corruption, and economic development
Authors: Zhang Miao , Zhang Houli , Zhang Li , Peng Xu , Zhu Jiaxuan , Liu Duochenxi , You Shibing 
Published: July 2023

AbstractCorruption and anti-corruption efforts are intertwined with political and economic concerns. From an economic and political perspective, as the government strives to enhance its governance capabilities, it becomes crucial to consider the costs of anti-corruption supervision and the losses incurred from corruption. This evaluation is essential for formulating a scientifically sound anti-corruption strategy that maximizes government benefits. To address this issue, the paper presents a model that incorporates levels of supervision and associated costs. The findings reveal that in the case of homogeneous officials, the optimal level of supervisory input, which maximizes government benefit, is nearly zero when per capita income is low due to budgetary constraints on anti-corruption control. However, as per capita income reaches a certain threshold, the optimal level of supervisory input suddenly rises to its maximum and decreases as per capita income increases. Alternatively, if the government adopts a zero-tolerance approach towards corruption and provides adequate remuneration to its employees, ensuring that all competent authorities can resist corruption, then corruption can be eliminated. Moreover, when officials exhibit heterogeneity in terms of their honesty levels, certain conditions give rise to a middle per capita income range, resulting in an optimal level of supervisory input that leads to a phenomenon known as “partial corruption.” During this phase, the wages paid by the government to its employees promote honesty, preventing them from engaging in corruption. However, they are unable to curb the corrupt activities of more dishonest officials. To some extent, this model also explains the challenges associated with eradicating corruption in several middle-income countries.
A comparison of physical image quality of two hologic digital mammography systems that utilise linear and 2D anti-scatter grids
Authors: Moore Craig S , Wood Tim J , Saunderson John R , Beavis Andrew W 
Published: July 2023

Abstract

Objective. Full-field digital mammography (FFDM) systems manufactured by Hologic that utilise either a 2D or linear anti-scatter grid have recently been installed in our clinic. The manufacturer advise that for matched dose, both grids deliver comparable image quality. The aim of this study was to test the manufacturer’s claim using advanced physical image quality metrics and to inform whether the different grids are indeed dose neutral. Approach. Effective detective quantum efficiency (eDQE), effective noise equivalent quanta (eNEQ) and effective dose efficiency (eDE) were measured on a Hologic Dimensions (2D grid) and a Hologic 3Dimensions (linear grid) FFDM system, both calibrated at installation to provide matched threshold contrast, according to the EUREF protocol. eDQE, eNEQ and eDE were calculated and compared using 2, 4, 6 and 7 cm thicknesses of poly (methyl methacrylate) (PMMA) to simulate a clinically appropriate range of breast thicknesses. The beam qualities (target/filter and kilovoltage) chosen were identical between the two systems. Main results. All image quality metrics investigated show that the 2D grid outperforms the linear grid across all spatial frequencies. Furthermore, mean glandular dose (MGD) must be increased by up to 38% on those units that utilise the linear grid if eNEQ is to be matched, although MGD to the standard breast remains within NHSBSP tolerance and below the UK diagnostic reference level. The gradient and shape of each curve was the same irrespective of which grid was used, suggesting that subtle lesions (low frequency information) and micro-calcifications (high frequency information) will be imaged just as efficiently with a linear or 2D grid. Significance. If image quality is to be matched between those units utilising 2D and linear grids, dose must be increased on the latter. This information will be useful to the medical physicist tasked with the optimisation and standardisation of Hologic FFDM units.