bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effect of Activity Participation in Middle-Aged and Older People on the Trajectory of Depression in Later Life: National Cohort Study
Authors: Gao Yan , Jia Zhihao , Zhao Liangyu , Han Suyue 
Published: March 2023

Background
More activity participation is an important means of handling depression and promoting positive aging, but the impact of changes in activity participation on the developmental trajectory of depression has not been fully studied.

Objective
The purpose of this study is to study the relationship between current activity participation and depression in middle-aged and older people (≥45 years old) and the relationship between activity participation and the developmental trajectory of depression in later life in China.

Methods
This study used data from the China Health and Retirement Longitudinal Study (CHARLS) across 7 years and included a total of 4818 middle-aged and older people (≥45 years old). Controlling for relevant control variables, the latent growth curve model and the cross-lag model were used to assess the effect of changes in activity participation on the depression trajectory in later life and the main lag relationship between activity participation and depression. Activity participation as well as depression were measured using the self-reported activity and health status based on the CHARLS questionnaire.

Results
Among the 4818 respondents, the mean values of physical activity participation, social leisure activity participation, and depression ranged from 76.98 (SD 15.16) to 83.95 (SD 5.72), from 7.43 (SD 8.67) to 9.25 (SD 10.16), and from 7.61 (SD 5.72) to 8.82 (SD 6.51), respectively. Our findings revealed that activity participation could be related to depression. Physical activity participation predicted initial depression (β=–0.631, P<.001) and its trajectory (β=0.461, P<.001). However, social leisure activity participation predicted initial depression (β=–0.223, P<.001) but did not predict its trajectory (β=0.067, P=.159). Finally, cross-lag regression analysis further demonstrated the predictive effect of activity participation on depression.

Conclusions
This study demonstrates the prediction of activity participation for future depression in the Chinese middle-aged and older populations. The data showed that activity participation is significantly associated with changes in depression and future depression among middle-aged and older people in China. The Chinese government should encourage middle-aged and older people to participate in various activities, which can effectively prevent the aggravation of depression and also have a positive significance for positive aging.
Vivir aquí, pero con la mirada hacia afuera. Entrevista a Gerardo Michelín
Authors: Alpern Giuliana 
Published: March 2023

Gerardo Michelín es una persona a quien le gusta meter las narices en muchos proyectos. Con el tiempo aprendió a ser menos disperso para poder concretar mejor sus propósitos. Considera que haber pasado por varias fases de la comunicación resultó una buena forma de aprendizaje, por más que el éxito quede a un lado por momentos.
Texto de Martín Natalevich. <i>La hermana</i>
Authors: Natalevich Martín 
Published: March 2023

Le había prometido que la próxima vez la iba a besar. Se lo dije, o lo hice para mis adentros, cuando bajé del auto. El vértice inferior de la puerta se trancó contra el cordón y yo me deslicé con el mismo sacrificio de las madres a punto de parir.
"Deixa eu te contar uma coisa...": Possibilidades do uso de narrativas e sua análise nas pesquisas em organizações
Authors: Zaccarelli Laura Menegon , Godoy Arilda Schmidt 
Published: March 2023

Let me tell you something ...": possible uses of narrative analysis in organizational research O artigo busca a compreensão e reflexão sobre o uso de análise de narrativas em pesquisas no contexto organizacional. Para atingir este objetivo esclarece e situa o conceito de narrativa e apresenta as possibilidades, cuidados e perspectivas ao se trabalhar com a sua análise no âmbito dos estudos organizacionais. Apresenta teoricamente o conceito de narrativas, os pressupostos que estão contidos nesta abordagem, e as orientações metodológicas. Trata a seguir do uso de narrativas nas pesquisas em organizações, apresentando um exemplo ilustrativo retirado de uma pesquisa de campo. Ao final o texto discute a utilidade do emprego da análise de narrativas no contexto da pesquisa organizacional.
CERTIFICAÇÃO DE SISTEMA DE GESTÃO AMBIENTAL: ALTERNATIVAS POSSÍVEIS
Authors: Aguiar Helder de Souza , Mello Adriana Marotti de , Nascimento Paulo Tromboni de Souza 
Published: March 2023

Os stakeholders cada vez mais pressionam as organizações a adotarem práticas voltadas a Gestão Ambiental. De forma a satisfazer seus anseios e se resguardar algumas adotam as certificações ambientais. A certificação ISO 14001 é a mais conhecida e utilizada. A pergunta que orientou este estudo foi se há uma necessidade de sempre se certificar o Sistema de Gestão Ambiental (SGA) da organização. Com base em um estudo qualitativo de caráter exploratório foram usadas três organizações com históricos diferentes que serviram de objeto da investigação. Nessas organizações encontramos uma certificada ISO 14001, uma segunda que abandonou a certificação e uma terceira, representante setorial, onde seus membros adotam uma certificação alternativa. Podemos afirmar que na amostra o mercado atendido é quem exerce a maior influência no momento da certificação. Como achado secundário, e relevante do ponto de vista dos praticantes, podemos argumentar que as certificações setoriais são uma alternativa tanto para as empresas que buscam acreditar-se quanto para as empresas compradoras.
Олон ханатай нүүрстөрөгчийн нанохоолой хүчилтэй харилцан үйлчлэх
Authors: Л Баярчимэг , Р Галбадрах , Ц Бямбасүрэн , Г Шилагарди 
Published: March 2023

Бид энэ ажлаар устөрөгчийн давхар исэл (H2O2 ) ба давсны хүчлийн(HCl) уусмалд нанохоолойгуусгахад азотын хүчлийн адил нанохоолойн битүү төгсгөлийг задалдаг болохыг ажиглав.
escola e eu
Authors: Cândido Renata Marcílio , Martins Edna 
Published: March 2023

Os altos índices de trabalhadores informais que ocupam as ruas dos grandes centros urbanos têm sido um fenômeno historicamente ligado à pobreza e às desigualdades socioeconômicas que ampliam a vulnerabilidade social. Com base nisso, o artigo apresenta a experiência de pesquisa que investigou trajetórias de escolarização de jovens e adultos em situação de trabalho informal. A partir de metodologia qualitativa, utilizando procedimentos de histórias de vida por meio de entrevistas, buscou-se compreender os sentidos atribuídos por trabalhadoras aos seus processos de escolarização. A análise dos dados indicou a ausência de vínculos entre as entrevistadas e os saberes e as culturas escolares, assim como a significação do fracasso escolar como algo individualizado com pouca ligação com o mundo da escola.
The clinical use of cannabidiol and cannabidiolic acid–rich hemp in veterinary medicine and lessons from human medicine
Authors: Ukai Masayasu , McGrath Stephanie , Wakshlag Joseph 
Published: March 2023

ABSTRACT
The endocannabinoid system (ECS) is an integral neuromodulatory system involved in neuronal development, synaptic plasticity, and homeostasis regarding immunity, as well as brain and other physiological functions such as anxiety, pain, metabolic regulation, and bone growth. Cannabis is a plant that contains exogenous cannabinoids, which have the potential for profound interplay within the ECS as enzymatic inhibitors or receptor-mediated interactions. Activation of cannabinoid receptors leads to various intracellular signaling processes that are involved in cellular functions, but those interactions are diverse due to different affinities of each cannabinoid with relevant receptors. Among the exogenous cannabinoids, cannabidiol (CBD) has drawn attention due to its potential anticancer, antiangiogenic, anti-inflammatory, and antiseizure properties using in vitro and in vivo models. Although scientific evidence is limited in dogs, there appears to be cautious optimism regarding the utilization of CBD in conjunction with other therapeutics for a range of disorders. This review will primarily focus on current scientific research on the efficacy of CBD on seizure, anxiety, osteoarthritis, and atopic dermatitis, following a brief discussion of endo- and exogenous cannabinoids, ECS, their molecular mechanism, and potential side effects in veterinary medicine. Cannabinoid pharmacology and pharmacokinetics will be addressed in the companion Currents in One Health by Schwark and Wakshlag, AJVR, May 2023.
Candida Auris: What do We Know about the Most Enigmatic Pathogen of the 21st Century?
Authors: Bogut Agnieszka 
Published: March 2023

Abstract

Candida auris is a new fungal pathogen whose clinical significance has dramatically increased within recent years. Major issues related to this species include its rapid global spread and high epidemic potential, resilience and persistence in the hospital environment favoured by its resistance against certain disinfectants, horizontal transmission; possibility of persistent colonization, challenging laboratory identification based on conventional biochemical methods, multidrug resistance as well as the need for implementation of restrictive and expensive prevention and control measures. This review raises the above mentioned issues and compiles recent findings regarding this microorganism.
Lipopolysaccharide Pantoea Agglomerans and Atopic Dermatitis, Allergic Contact Dermatitis and Wound Healing
Authors: Kiecka Aneta , Szczepanik Marian 
Published: March 2023

Abstract
Lipopolysaccharide (LPS) is found in most Gram-negative bacteria and induces innate responses by binding to toll-like receptor 4 (TLR4). LPS isolated from Pantoea agglomerans species is an interesting issue. On the one hand, it is a risk factor for diseases such as wounds, abscess, bacteremia, pneumonia, urinary tract infections, septic arthritis, osteomyelitis and peritonitis. On the other, its health-promoting properties in atherosclerosis, Alzheimer’s disease, and osteoporosis are increasingly observed. Studies in humans and animal models show that LPS from P. agglomerans may have beneficial effects in the treatment of certain diseases. A huge challenge today is the prevention and treatment of skin diseases, including atopic dermatitis (AD), allergic contact dermatitis (ACD), and hard-to-heal wounds. Reports show that LPS from P. agglomerans may be useful in the treatment of skin diseases through its effects on the immune response. Studies show that LPS acts on Langerhans cells and leads to suppression of the allergic response.
Microbial Culture Collections and Microbiological Biobanks in the Context of New ISO Standards
Authors: Jaroszewska Ewelina , Nasiłowska Justyna , Sokołowska Barbara 
Published: March 2023

Abstract
In order to meet the growing needs of the world economy for biotechnology, culture collections must transform the way they operate from passive storage of microbial resources to active microbial resource centers whose services should go beyond the provision of microbes. The protection and conscious use of microorganisms aims to co-create a strategy for responsible and sustainable development, based on expert knowledge. This article deals with the subject of the recently developed panel of biobank-specific standards and the requirements that must be met by culture collections to transform into modern microbial biobanks.
Innovative Dynamics and Structural Changes in the Manufacturing Industry of the Volga-Ural Macro-Region
Authors: Preobrazhensky Yu. V. 
Published: March 2023

The article discusses formation of an innovation system within the Volga-Ural macro-region. The scientific novelty of the work lies is the methodology for determining the flexibility of innovative component of the manufacturing industry in the region. The relevance of the research is determined by the need for a paradigm shift to the analysis of horizontal integration of regions, including in terms of innovation. Such integration will create prerequisites for an active flow of knowledge and the spread of innovations. The main properties of the territorial innovation system are formulated, including openness, innovation orientation, structural flexibility, and internal connectivity. The requirements for the functions and regional parameters in such a system are justified, and the advantages of large regions-subjects of the Russian Federation as innovative cores are emphasized.The main research methods, in addition to structural and spatial analysis and synthesis, were the calculation of structural coefficients in the economy and scientific and applied sphere for the Volga-Ural macro-region (Orenburg, Penza, Saratov, Samara and Ulyanovsk regions and the Republic of Bashkortostan). In particular, we use the Ryabtsev index, the coefficient of specialization (per capita production), and the coefficient of the use of advanced production technologies. The article analyzes structural shifts in innovative production in the manufacturing industries of these regions in the period 2010– 2019. This tool allows us to study the degree of manufacturing flexibility of the RF subjects of the Volga-Ural macro-region and the dynamics of their innovative development (ascending or descending) as well as the degree of its co-directionality.The analysis shows heterogeneity of the macro-region in economic and innovative terms. The regions that differ most from others in the structure of the innovation industry are identified (Bashkortostan and the Orenburg region). It is shown that the most positive dynamics is typical of Bashkortostan whereas a number of other regions face innovation degradation. The article considers the prospects of Ulyanovsk and Samara regions as generators of knowledge and innovation in the macro-region.The results of the study can be used in business (identifying the region with the most flexible economic structure as an innovative attractive one) and in state spatial planning (determining the composition of macro-regions). Such research is relevant for any macro-regions in the country.
Problems of Implementing National Projects at Municipal Level
Authors: Goryachenko E. E. , Malov K. V. 
Published: March 2023

The article analyzes the problems of implementing national projects at the municipal level. Based on the materials of the next wave of the annual expert survey of heads of municipalities conducted by the authors in March-April 2020 as part of monitoring the socio-economic situation in Russian municipalities. The author assesses the current situation, shows its distinctive features and trends in the context of the dynamics of the last decade, identifies the main problems that arise in municipalities in modern conditions during the implementation of national projects and possible ways to solve them. It is shown that serious barriers to the implementation of national projects at the municipal level, in addition to the wellknown problem of financial support, are the imperfection of the regulatory framework, insufficient methodological and information support, organizational difficulties, as well as personnel problems that significantly complicate the implementation of specific activities. The main obstacles to the implementation of national projects at the local level are weak coordination, inconsistency of actions of various bodies, centralization of managerial influences, as well as limited and insufficient certainty of the powers of local self-government bodies in the implementation of national projects. It is concluded that it is necessary to improve the mechanisms of interaction between regional and local authorities, aimed at significantly increasing the role assigned to local governments in the implementation of national projects. An important basis for decision-making in the development and evaluation of the effectiveness of national projects should be taking into account the opinions of heads of municipalities on the basis of sociological monitoring of the socio-economic situation and evaluating the effectiveness of measures taken to resolve problems at the municipal level.
The Study on Knowledge Self-Organization and Technological Structure of the Russian Regions by Means of Kohonen’s Self-Organizing Maps
Authors: Zabolotsky A. A. 
Published: March 2023

The article proposes a novel model for assessing the quality of technological development which differs from the similar spillovers by introducing a fundamentally new parameter of knowledge selforganization. Unlike spillovers measuring financial R&D flows, knowledge spillover measures structural similarities presented in patents, articles and other quantized units. Being the results of the reactions on the emergence of technological tasks and absorbing new technologies themselves, patents reflect real industrial picture of distribution of new technologies in any particular area. Implementation of selforganizing neural maps unveiled strong self-organized structural patterns distributed across the Russian Federation which were undetectable by means of conventional spatial econometric methods. Furthermore, neural maps exposed serious drawbacks of the Russian knowledge flow system, which is a drastic lack of flow in several high tech areas such as biotechnology. Self-organization indicator can be applied for evaluation of Megascience projects or other programs on both regional and federal levels. The structure of regional technologies based on 24 technological areas is studied and mapped on neural model, thereby it has been hypothesized that self-organization has an effect on qualitative processes of technological development. The study presents validation model of this hypothesis based on Kohonen’s self-organizing maps. Enhancement of this model on the further spatial studies is shown. Knowledge self-organization variable is developed to indicate technology integration and emergence.
The Influence of Cost Leadership Strategy, Difference and Focus on the Performance of the Company at PT. Pwi
Authors: Restiana Ina 
Published: March 2023

The purpose of this study is to determine the effect of cost leadership strategy, differentiation strategy and focus strategy on company performance. The case study in this study was taken from PT. PWI, which is a manufacturing company engaged in the production of shoes and footwear. The population taken in this study, namely the employees of PT. PWI with a sample of 96 respondents who work within the scope of PT. PWI.
The dependent variable (Y) in this study is company performance, while the independent variable (X) includes: Cost advantage strategy (X1), Differentiation Strategy (X2) and Focus Strategy (X3). Data analysis method using path analysis with IBM SPSS statistics 16 program which is fully carried out by the author and also related parties. The results of this study indicate that the cost advantage strategy, differentiation strategy and focus strategy have a positive and significant impact on company performance. The differentiation strategy is the most influential strategy compared to the other two strategies.
Strategi Inovasi dalam Media Pembelajaran Model Daring dalam Menanggulangi Covid-19
Authors: Maulani Emi , Yulisda Desvina , Ula Mutammimul , Saputra Eri , Pratama Angga , Zurhijjah Zurhijjah 
Published: March 2023

Peningkatan kualitas program pembelajaran perlu dilandasi dengan kegiatan belajar-mengajar yang efisien dan efektif. Strategi dalam pendidikan merupakan suatu proses untuk meningkatkan kecerdasan siswa pada masa pandemi ini. Perkembangan teknologi dan komunikasi pada dunia pendidikan membutuhkan proses pelatihan dan pembelajaran menggunakan berbagai metode (E-Learning, Zoom, Google Classroom, Schoology, dan Edmodo). Proses ini menggunakan kegiatan pelatihan dan pengajaran. Prosesnya ini tidak terkendala apapun karena dapat diakses dan diproses kapan saja dan di mana saja. Proses ini mendukung kebijakan Kementerian Pendidikan dan Kebudayaan Indonesia terkait proses pembelajaran dan mendeka belajar selama pandemic covid-19. Permasalahan yang sering dihadapi pada dunia pendidikan, pembelajaran selama ini yang kurang efektif. Metode penyampaian materi yang diberikan belum efektif dalam pemanfaatan sumber belajar, penyampaian materi oleh guru secara jadwal mengajar kurang baik sehingga penyerapan materi untuk siswa kurang diterima. Metode pelaksanaan pengabdian ini dengan menggunakan teori dan praktik. Hasil dari proses pelatihan ini dapat memberikan inovasi pembelajaran secara daring dengan penggunaan berbagai tools berbagai tools yang digunakan dan meningkatkan kemampuan guru untuk mengimplementasikannya dapat meningkatkan proses belajar mandiri.
Peningkatan Pengetahuan dan Ketrampilan Hospitality pada Kelompok Wisata di Desa Budo, Kecamatan Wori Kabupaten Minahasa Utara
Authors: Towoliu Benny Irwan , Polii Bernadain Dainty , Mandulangi Jufrina 
Published: March 2023

Sikap hospitality sangat dibutuhkan oleh masyarakat lokal ketika desa tempat tinggal mereka akan dijadikan sebagai desa wisata. Sikap ini sangat berhubungan dengan cara masyarakat dalam menyambut tamu yang datang bahkan menginap di desa wisata. Tujuan dari program pelatihan ini adalah untuk meningkatkan pengetahuan dan ketrampilan hospitality pada kelompok wisata di Desa Budo, kecamatan wori Kabupaten minahasa utara. Metode pelatihan dillakukan dalam bentuk: system pengajaran, simulasi melalui bermain peran, dan pada akhir pelatihan dilakukan evaluasi terhadap keseluruhan materi yang diajarkan. Hasil yang diharapkan adalah peningkatan pengetahun dan ketrampilan dari kelompok wisata dan berdampak secara secara luas bagi masyarakat local di Desa Budo.
O CEFAPRO E A FORMAÇÃO PERMANENTE NO CONTEXTO DA ESCOLA PÚBLICA
Authors: Carvalho Ademar de Lima 
Published: March 2023

O presente texto tem como objetivo produzir uma reflexão sobre a importância do Centro de Formação e Atualização dos profissionais da educação básica (CEFAPRO), enquanto instrumento de mediação no processo de formação permanente no contexto da escola pública. Refletir sobre a formação de professor centrada na escola no contexto do Centro de Formação, necessariamente, precisa estar articulada a um projeto político de formação consubstanciada a uma concepção de mundo, ser humano, professor, educação e escola na dimensão da qualidade social.Como pressuposto teórico o texto se fundamenta no pensamento educativo de Paulo Freire. Para análise sobre a formação permanente a reflexão embasa no diálogo pedagógico de autores freiriano. Como resultado da reflexão, tem-se a intenção que o texto possa contribuir com a produção da crítica, problematização e afirmação sobre a importância do CEFAPRO como centro de formação permanente de política e pedagógica dos trabalhadores da educação pública.
EDUCAÇÃO POPULAR E TRABALHO ASSOCIADO NUM PROGRAMA DE PÓS-GRADUAÇÃO STRICTO SENSU EM EDUCAÇÃO-NÍVEL MESTRADO NO INTERIOR DO BRASIL: UM DIÁLOGO NECESSÁRIO
Authors: Sguarezi Sandro Benedito , Dutton Aline Pereira , Martins Elei Chavier 
Published: March 2023

O objetivo do artigo foi verificar a importância da disciplina Educação Popular e Trabalho Associado ofertada no Programa de Pós-graduação Stricto Sensu em Educação – Mestrado na Universidade do Estado de Mato Grosso (UNEMAT), alocada na Linha de Pesquisa: Educação e Diversidade. O estudo questiona quais os limites e possibilidades da disciplina na formação política dos mestrandos matriculados no período de 2013 a 2015? É uma pesquisa qualitativa e usou técnicas de: pesquisa bibliográfica, observação documental e questionário. Foi possível inferir que a disciplina contribuiu com pesquisas para aprofundar o diálogo sobre o tema, tornando-se uma possibilidade para a construção da autonomia e conhecimento dos mestrandos, o que evidencia a disciplina como instrumento de reflexão e formação. Contudo, existem limites a serem superados para atingirmos uma educação emancipatória, que cumpra os pressupostos da Educação Popular e do Trabalho Associado. Isto posto, há muito o que aprender com as experiências de autogestão.