bluuebunny/crossref_metadata_2025_split huggingface dataset:
Wissensstand und Fehlvorstellungen zu Vorsorgedokumenten – Ergebnisse einer Bürgerbefragung
Authors: Fleischmann Carolin , Henking Tanja , Neuderth Silke 
Published: August 2023

Zusammenfassung
Einleitung
Vorsorgedokumente wie Patientenverfügung oder Vorsorgevollmacht sind bedeutsame Instrumente der Vorausplanung für Situationen, in denen ein Mensch nicht mehr für sich selbst entscheiden kann. Obwohl immer mehr Bürger:innen in Deutschland solche Dokumente erstellen, ist über ihr Wissen zu Zweck, Arten und Anwendung von Vorsorgedokumenten wenig bekannt. Nach über 10 Jahren seit der gesetzlichen Verankerung der Patientenverfügung soll diese Studie das Wissen von Bürger:innen erfassen und Wissenslücken detektieren.

Methoden
In der Stadt und im Landkreis Würzburg wurde 2021 eine Querschnittsbefragung von volljährigen Bürger:innen u. a. zu Besitz, Umgang mit und Wissensstand zu Vorsorgedokumenten durchgeführt. Die Rekrutierung erfolgte über Werbeanzeigen und lokale Netzwerke.

Ergebnisse
Von den 282 Befragten (MAlter = 50 J., zu 2 Drittel weiblich) hatten 43,4 % nach Selbstangabe zumindest ein Vorsorgedokument verfasst. Im Wissenstest wurden im Mittel 22/34 Punkten erreicht. Fragen zur konkreten Anwendung von Vorsorgedokumenten anhand eines Fallbeispiels sowie zu Sterbehilfearten wurden häufig korrekt beantwortet, wohingegen beim Faktenwissen zu den einzelnen Dokumenttypen größere Wissensdefizite bestanden. Objektiv getestetes Wissen und Variablen zum subjektiven Wissensstand korrelieren positiv.

Diskussion
Die relativ hohe Quote an erstellten Dokumenten in dieser Stichprobe ist Ausdruck ihrer raschen Verbreitung in den letzten Jahren. Das Wissensniveau ist als niedrig einzuschätzen und zeigt Fehlvorstellungen zu Rechten und Pflichten der verfassenden Person sowie der beteiligten Akteure. Das gemessene Wissen der Bürger:innen steht in Diskrepanz zum häufig geäußerten Wunsch, durch informiertes Erstellen von Vorsorgedokumenten ihre Selbstbestimmung zu wahren.
Grain yield and adaptation of spring wheat to Norwegian growing conditions is driven by allele frequency changes at key adaptive loci discovered by genome-wide association mapping
Authors: Mroz Tomasz , Dieseth Jon Arne , Lillemo Morten 
Published: August 2023

Abstract
Key message
Adaptation to the Norwegian environment is associated with polymorphisms in the Vrn-A1 locus. Historical selection for grain yield in Nordic wheat is associated with TaGS5-3A and TaCol-5 loci.

Abstract
Grain yields in Norwegian spring wheat increased by 18 kg ha−1 per year between 1972 and 2019 due to introduction of new varieties. These gains were associated with increments in the number of grains per spike and extended length of the vegetative period. However, little is known about the genetic background of this progress. To fill this gap, we conducted genome-wide association study on a panel consisting of both adapted (historical and current varieties and lines in the Nordics) and important not adapted accessions used as parents in the Norwegian wheat breeding program. The study concerned grain yield, plant height, and heading and maturity dates, and detected 12 associated loci, later validated using independent sets of recent breeding lines. Adaptation to the Norwegian cropping conditions was found to be associated with the Vrn-A1 locus, and a previously undescribed locus on chromosome 1B associated with heading date. Two loci associated with grain yield, corresponding to the TaGS5-3A and TaCol-5 loci, indicated historical selection pressure for high grain yield. A locus on chromosome 2A explained the tallness of the oldest accessions. We investigated the origins of the beneficial alleles associated with the wheat breeding progress in the Norwegian material, tracing them back to crosses with Swedish, German, or CIMMYT lines. This study contributes to the understanding of wheat adaptation to the Norwegian growing conditions, sheds light on the genetic basis of historical wheat improvement and aids future breeding efforts by discovering loci associated with important agronomic traits in wheat.
Utilization of by-products for preparation of Pickering particles
Authors: Muiz Abdul , Klojdová Iveta , Stathopoulos Constantinos 
Published: August 2023

AbstractThe processing of foods yields many by-products and waste. By-products are rich in bioactive components such as antioxidants, antimicrobial substances, polysaccharides, proteins, and minerals. A novel use of by-products is as materials for the preparation of Pickering particles. Pickering particles are considered appropriate materials for the stabilization of emulsions. Conventionally, emulsions are stabilized by the addition of stabilizers or emulsifiers which decrease the surface tension between phases. Emulsifiers are not always suitable for some applications, especially in foods, pharmaceuticals, and cosmetics, due to some health and environmental problems. Instead of emulsifiers, emulsions can be stabilized by solid particles also known as Pickering particles. Pickering emulsions show higher stability, and biodegradability, and are generally safer than conventional emulsions. Particle morphology influences emulsion stability as well as the potential utilization of emulsions. In this review, we focused on the by-products from different food industries (cereal and dairy) that can be used as materials for preparing Pickering particles and the potential of those Pickering particles in stabilizing emulsions.
Surgical treatment of internal hernia after Roux–en-Y gastric bypass — impact of institutional standards and surgical approach
Authors: Kollmann Lars , Lock Johan F. , Kollmann Cathérine , Vladimirov Miljana , Germer Christoph-Thomas , Seyfried Florian 
Published: August 2023

Abstract
Introduction
Internal hernia is one of the most frequent long-term complications after laparoscopic gastric bypass surgery (RYGB). Surgical treatment of an internal hernia itself has risks that can largely be avoided by the implementation of institutional standards and a structured approach.

Material and methods
From 2012 until 2022, we extracted all consecutive bariatric cases from the prospectively collected national database (StuDoQ). Data from all patients undergoing internal hernia repair were then collected from our hospital information management system and retrospectively analyzed. We compared patient characteristics and surgical outcome of patients before and after the implementation of standard operating procedures for institutional and perioperative aspects (first vs. second time span).

Results
Overall, 37 patients were identified (median age 43 years, 86.5% female). Internal hernia was diagnosed after substantial weight loss (17.2 kg/m2) and on average about 34 months after RYGB. Baseline characteristics (age, sex, BMI, achieved total weight loss% and time interval to index surgery were comparable between the two groups). After local standardization, the conversion rate decreased from 52.6 to 5.6% (p = 0.007); duration of surgery from 92 to 39 min (p = 0.003), and length of stay from 7.7 to 2.8 days (p = 0.019).

Conclusion
In this study, we could demonstrate that the surgical therapy of internal hernia after gastric bypass can be significantly improved by implementing institutional and surgical standards. The details described (including a video) may provide valuable information for non-specialized surgeons to avoid pitfalls and improve surgical outcomes.
The molecular weight of hyaluronic acid influences metabolic activity and osteogenic differentiation of periodontal ligament cells
Authors: Frasheri Iris , Tsakiridou Nikoletta Dimitra , Hickel Reinhard , Folwaczny Matthias 
Published: August 2023

Abstract
Objective
While HA is present naturally in periodontal tissues, its molecular weight can vary widely in vivo. The objective of this study was to directly compare the biological reactions of periodontal ligament cells to four distinct molecular weights of hyaluronic acid (HA).

Materials and methods
Immortalized human periodontal ligament cells (PDL-hTERT) were cultured for 21 days in culture medium alone (control) or enriched with osteogenic supplements (OS group). Other 4 experimental groups were cultured in OS medium with the addition of HA with different molecular weights (HMW, MMW, LMW, and ULMW). The cell morphology was examined daily. WST1 assays were performed to evaluate metabolic activity. Von Kossa staining and calcium deposition assay were used to analyze osteogenic differentiation and mineralization.

Results
Cell morphology remained unaltered in all groups. Cells stimulated with OS alone or with the addition of hyaluronan showed all the typical microscopic appearance of osteogenic differentiation. Metabolic activity increased in all groups over time. Hyaluronan stimulated greater metabolic activity than the control group, with LMW HA and MMW HA showing the most significant increase. All groups showed mineral deposits and calcium deposition after 21 days of stimulation.

Conclusion
Our results suggest that hyaluronan can promote metabolic activity and mineralization of PDL-hTERT cells, with LMW HA being the most effective.

Clinical relevance
These results shed light on how the various molecular weight fractions of HA promote tissue regeneration and repair, as well as help to identify an optimal molecular weight range for this application in periodontal tissues.
The investigation of treatment design parameters on carbon integration networks
Authors: Alnouri Sabla Y. , Al-Mohannadi Dhabia M. 
Published: August 2023

AbstractCarbon Integration methods help identify the appropriate allocation of captured carbon dioxide (CO2) streams into CO2-using sinks, and are especially useful when a number of CO2 sink options are present simultaneously. The method helps identify CO2 allocation scenarios when subjected to an emission target on the CO2 overall network. Many carbon dioxide sink options are costly, and more often than not, require a high purity carbon dioxide source to satisfy the sink demand. Hence, it is imperative to effectively incorporate treatment units in such networks, to obtain high-purity CO2 streams. In fact, it has been previously reported in many studies that the most expensive step in Carbon Capture, Utilization and Sequestration (CCUS) is the treatment system. As a result, this paper focuses on reassessing the performance of carbon integration networks using a more rigorous cost model for the treatment design stage. The effect of utilizing different treatment operating conditions on the overall cost of the treatment stage of CO2 (before allocation) is first captured using a detailed cost model. Subsequently, this information is then fed into a network design problem that involves a CO2 source-sink allocation network problem, and different CO2 net capture targets within the network. For this, an enhanced treatment model that captures all necessary treatment design parameters has been utilized alongside the original model. The original carbon integration formulation has been adopted from previous work. Many of the cost items have been lumped into single parameters in the original formulation, and lack the necessary depth required to carry out the necessary investigations for this work. Hence, the treatment model introduced in this paper is more rigorous, as it accounts for important technical performance constraints on the system to be assessed. Utilizing a more detailed cost model was found to be very helpful in understanding several effects of varying parameters on the overall source-sink allocations, when subjected to different CO2 net emission reduction targets. The cost of the carbon network increases when the solvent temperatures are increased. However, there was a noticeable linear trend at lower temperatures compared to higher temperatures, where the increase became non-linear. Furthermore, it was discovered that for net capture targets of 20% and 25%, no revenue from carbon storage could be generated beyond a solvent temperature of 25 °C. Additionally, the optimal diameter of the treatment column was more responsive to changes in solvent temperature for cases with low net capture targets (below 10%), while its sensitivity decreased for higher capture targets (above 10%).
Graphical Abstract
Long-term safety and efficacy of a foldable iris-fixated phakic intraocular lens for the correction of myopia
Authors: Royo Mariano , Jiménez Ángel , Piñero David P. 
Published: August 2023

Abstract
Purpose
To analyze and report the long-term outcomes in terms of efficacy and safety of eyes implanted with the spherical version of a foldable iris-fixated phakic intraocular lens (pIOL) for the correction of myopia.

Methods
Retrospective analysis of the results of 56 eyes of 32 patients (age, 19–45 years) who underwent implantation of the spherical model of the Artiflex pIOL (Ophtec B.V., Groningen, The Netherlands) for the correction of myopia. Visual, refractive, biometric, intraocular pressure (IOP) and corneal endothelial changes were evaluated during a long-term follow-up: 2, 7, 10 and 12 years for more than 50, 30, 20 and 10 eyes, respectively.

Results
At 4 weeks postoperatively, a significant reduction of manifest sphere and spherical equivalent (SE), with a significant improvement of uncorrected distance visual acuity were found (all p < 0.001). No significant changes were found during the rest of follow-up in sphere (p ≥ 0.072). The percentage of eyes with SE within ± 1.00 D was over 83% during the whole follow-up. A non-significant trend to IOP increase was observed at 4 weeks postoperatively (p = 0.530), with a significant reduction at 1 year after (p = 0.039) and no significant changes during the rest of follow-up (p = 0.180). There was a significant reduction of anterior chamber depth at 4 weeks after surgery (p < 0.001), with no significant changes during the following 9 years of follow-up (p = 0.118). However, an additional significant decrease of this parameter was observed between 10 and 13 years after surgery (p = 0.027). Mean endothelial cell loss changed from 2.01 ± 4.49% at 4 weeks after surgery to 9.11 ± 2.24% at the end of the follow-up. No complications were reported during the follow-up.

Conclusions
Myopia correction with the Artiflex pIOL is an effective and safe procedure in the long term.
Digitalization, inter-organizational collaboration, and technology transfer
Authors: Adomako Samuel , Nguyen Nguyen Phong 
Published: August 2023

AbstractIn this study, we explore the impact of business process digitalization on technology transfer intensity through the mediating mechanism of inter-organizational collaboration. Using data collected from 211 firms in Vietnam, we find that: (1) digitalization positively influences inter-organizational collaboration, (2) inter-organization collaboration positively affects technology transfer intensity, (3) the effect of inter-organizational collaboration on technology transfer intensity is amplified when technology commercialization potential is high, and (4) the effect of digitalization on technology transfer intensity is mediated by inter-organizational collaboration. These findings suggest that technology commercialization potential is a critical moderating factor that needs to be considered in the context of technology transfer, and its interaction with inter-organizational collaboration should be carefully managed to maximize the benefits of technology transfer. The study provides practical implications for technology firms seeking to enhance their technology transfer outcomes.
Values, decision-making and empirical bioethics: a conceptual model for empirically identifying and analyzing value judgements
Authors: Mertz Marcel , Prince Ilvie , Pietschmann Ines 
Published: August 2023

AbstractIt can be assumed that value judgements, which are needed to judge what is ‘good’ or ‘better’ and what is ‘bad’ or ‘worse’, are involved in every decision-making process. The theoretical understanding and analysis of value judgements is, therefore, important in the context of bioethics, for example, to be able to ethically assess real decision-making processes in biomedical practice and make recommendations for improvements. However, real decision-making processes and the value judgements inherent in them must first be investigated empirically (‘empirical bioethics’). For this to succeed, what exactly a ‘value judgement’ is and of what components it might consist must initially be theoretically clarified. A corresponding conceptual model can then support or even enable empirical data collection and analysis and, above all, subsequent ethical analysis and evaluation. This paper, therefore, presents a value judgement model with its theoretical derivation. It also illustrates its application in an interview study of decision-making between animal experimentation and alternative methods in the context of biomedical research. Though the model itself can be theoretically deepened and extended, the application of the model works in general and helps to uncover what value judgements can enter into decision-making. However, the empirical methods, for example, qualitative interviews, can also be better oriented towards eliciting value judgements (as understood according to the model). Further applications of the model to other topics or by means of other empirical methods are conceivable.
Soliton, periodic and superposition solutions to nonlocal (2+1)-dimensional, extended KdV equation derived from the ideal fluid model
Authors: Rozmej Piotr , Karczewska Anna 
Published: August 2023

AbstractWe present new (2+1)-dimensional extended KdV (KdV2) equation derived within an ideal fluid model. Next, we show several families of analytic solutions to this equation. The solutions are expressed by functions of argument $$\xi = (k x +l y-\omega t)$$

ξ
=
(
k
x
+
l
y
-
ω
t
)

. We found the soliton solutions in the form $$A\,\text {sech}^{2}(\xi )$$

A

sech
2

(
ξ
)

, periodic solutions in the form $$A\,\text {cn}^{2}(\xi ,m)$$

A

cn
2

(
ξ
,
m
)

and superposition solutions in the form $$\frac{A}{2}[\text {dn}^{2}(\xi ,m)\pm \sqrt{m}\,\text {cn}(\xi ,m)\text {dn} (\xi ,m)]$$

A
2

[

dn
2

(
ξ
,
m
)

±

m

cn

(
ξ
,
m
)

dn

(
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,
m
)

]

analogous to the solutions of (1+1)-dimensional, extended KdV equation and to the solutions to ordinary Korteweg-de Vries equation. On the other hand, the existence of these families of analytical solutions for the highly nonlinear non-local (2+1)-dimensional, extended KdV equation is astounding. The existence of essentially one-dimensional solutions to the (2+1)-dimensional extended KdV equation explains the enormous success of the one-dimensional nonlinear wave equations for the shallow water problem.
In Defence of Necessity
Authors: Uniacke Suzanne 
Published: August 2023

AbstractThis paper disputes Uwe Steinhoff’s view that a jus ad bellum requirement of necessity can be merged with a condition of proportionality. It argues that the proposed merger detracts from a conceptual and moral understanding of the structure and rationale of both the necessity and the proportionality considerations applicable in a range of moral contexts, including those of war and so-called lesser evils cases, where these conditions are intended as action-guiding.
Decision-making in the capital budgeting context: effects of type of decision aid and increases in information load
Authors: Hartmann Maren , Weißenberger Barbara E. 
Published: August 2023

AbstractThis paper sheds light on the question of whether a rules-based or general principles-based decision aid is preferable in the context of increased information load by experimentally investigating how different types of decision aids interact with increases in information load in a structured capital budgeting decision-making task. The experiment employed a 2 × 2 between-subjects design and was run in a course on management control systems with 136 master’s degree students at a German university. Subjects were tasked with reviewing investment proposals that contained differing amounts of information (low vs. high information load, i.e., irrelevant information cues in addition to those relevant for the decision). The second manipulation referred to the type of decision aid—either a detailed, rules-based capital budgeting guideline with clear cut-off rates, or the advice to employ generally accepted criteria for investment decision-making. The dependent variables investigated were perceived task complexity, decision accuracy, and decision confidence. Increases in information load and provision of a decision aid based on general principles led to an increase in perceived task complexity. There was only limited evidence for experimental conditions affecting decision accuracy, but the group of subjects relying on the rules-based capital budgeting guideline reported significantly higher decision confidence.
Wavelength and texture feature selection for hyperspectral imaging: a systematic literature review
Authors: Rogers Mitchell , Blanc-Talon Jacques , Urschler Martin , Delmas Patrice 
Published: August 2023

AbstractOver the past two decades, hyperspectral imaging has become popular for non-destructive assessment of food quality, safety, and crop monitoring. Imaging delivers spatial information to complement the spectral information provided by spectroscopy. The key challenge with hyperspectral image data is the high dimensionality. Each image captures hundreds of wavelength bands. Reducing the number of wavelengths to an optimal subset is essential for speed and robustness due to the high multicollinearity between bands. However, there is yet to be a consensus on the best methods to find optimal subsets of wavelengths to predict attributes of samples. A systematic review procedure was developed and applied to review published research on hyperspectral imaging and wavelength selection. The review population included studies from all disciplines retrieved from the Scopus database that provided empirical results from hyperspectral images and applied wavelength selection. We found that 799 studies satisfied the defined inclusion criteria and investigated trends in their study design, wavelength selection, and machine learning techniques. For further analysis, we considered a subset of 71 studies published in English that incorporated spatial/texture features to understand how previous works combined spatial features with wavelength selection. This review ranks the wavelength selection techniques from each study to generate a table of the comparative performance of each selection method. Based on these findings, we suggest that future studies include spatial feature extraction methods to improve the predictive performance and compare them to a broader range of wavelength selection techniques, especially when proposing novel methods.
Cardiac Arrhythmias in Oncological Patients—Epidemiology, Risk Factors, and Management within the Context of the New ESC 2022 Guidelines
Authors: Gawlik Michał , Zimodro Jakub Michal , Gąsecka Aleksandra , Filipiak Krzysztof J. , Szmit Sebastian 
Published: August 2023

Abstract
Purpose of Review
To provide an update on epidemiology, risk factors, and management of cardiac arrhythmias in oncological patients within the context of the new European Society of Cardiology 2022 guidelines on cardio-oncology.

Recent Findings
One of the side effects of different chemotherapeutics is their pro-arrhythmic activity. Both atrial and ventricular arrhythmias may be induced by cancer itself or by anticancer treatment. Recent studies report on the cardiotoxic activity of such promising therapies as BRAF and MEK inhibitors, or CAR-T therapy.

Summary
Risk factors of arrhythmias in oncological patients overlap with cardiovascular diseases risk factors, but there are some groups of anticancer drugs that increase the risk of cardiotoxicity. It is crucial to be aware of the risks associated with the oncological treatment and know how to act in case of cardiotoxicity.