bluuebunny/crossref_metadata_2025_split huggingface dataset:
The role of the glycome in symbiotic host-microbe interactions
Authors: Aminov Rustam , Aminova Leila 
Published: September 2023

Abstract
Glycosylation plays a crucial role in many aspects of cell biology, including cellular and organismal integrity, structure-and-function of many glycosylated molecules in the cell, signal transduction, development, cancer, and in a number of diseases. Besides, at the inter-organismal level of interaction, a variety of glycosylated molecules are involved in the host-microbiota recognition and initiation of downstream signalling cascades depending on the outcomes of the glycome-mediated ascertainment. The role of glycosylation in host-microbe interactions is better elaborated within the context of virulence and pathogenicity in bacterial infection processes but the symbiotic host-microbe relationships also involve substantive glycome-mediated interactions. The works in the latter field have been reviewed to a much lesser extent, and the main aim of this mini-review is to compensate for this deficiency and summarise the role of glycomics in host-microbe symbiotic interactions.
Body mass index effect on long-term survival after coronary artery bypass surgery: a competing risk analysis
Authors: Abreu Armando , Máximo José , Saraiva Francisca , Leite-Moreira Adelino 
Published: September 2023

Abstract

OBJECTIVES
The aim of this sudy was to investigate the presence of an obesity paradox on the long-term mortality of patients undergoing primary isolated coronary artery bypass surgery and to uncover whether any discrepancy found could be attributable to cardiovascular or noncardiovascular causes.

METHODS
Retrospective analysis of 5242 consecutive patients with body mass index (BMI) over 18.5 kg/m2 undergoing primary isolated coronary artery bypass surgery, performed from 2000 to 2015, in a Portuguese level III Hospital. The primary end point was long-term all-cause mortality. Secondary outcomes were long-term cause-specific mortality (cardiovascular and noncardiovascular). We fitted overall, and cause-specific hazard models, with BMI forced both as a categorical (using World Health Organization predefined cutoffs) and as a continuous variable.

RESULTS
Follow-up was 99.7% complete. The median follow-up time was 12.79 years (interquartile range, 9.51–16.61). The cumulative incidence functions failed to uncover any difference in 15-year all-cause (log-rank test, P = 0.400), cardiovascular (Gray's test, P = 0.996) and noncardiovascular mortality (Gray's test, P = 0.305) between BMI categories. Likewise, extensive multivariable-adjusted Cox regression and cause-specific hazards models failed to demonstrate in-between category differences, with BMI forced as a categorical variable. On the other hand, using BMI as a continuous variable, the model identified the optimal BMI as between 25.8 and 30.3 kg/m2 (nadir around 28.9 kg/m2), albeit this was dependent on the definition of the reference value.

CONCLUSIONS
In this longitudinal, population-level analysis of patients undergoing isolated primary coronary artery bypass grafting, we could not attest to any protective effect of obesity on long-term survival.
The Fading of the Mpox Outbreak Among Men Who Have Sex With Men: A Mathematical Modelling Study
Authors: Xiridou Maria , Miura Fuminari , Adam Philippe , Op de Coul Eline , de Wit John , Wallinga Jacco 
Published: September 2023

Abstract

Background
In the Netherlands, the number of mpox cases started declining before mpox vaccination was initiated. Most cases were men who have sex with men (MSM). We investigated whether the decline in mpox could be attributed to infection-induced immunity or behavioral adaptations.

Methods
We developed a transmission model and accounted for possible behavioral adaptations: fewer casual partners and shorter time until MSM with mpox refrain from sexual contacts.

Results
Without behavioral adaptations, the peak in modelled cases matched observations, but the decline was less steep than observed. With behavioral adaptations in the model, we found a decline of 16%–18% in numbers of casual partners in June and 13%–22% in July 2022. Model results showed a halving of the time before refraining from sex. When mpox vaccination started, 57% of MSM with very high sexual activity in the model had been infected. Model scenarios revealed that the outbreak could have waned by November 2022 even without vaccination.

Conclusions
The limited duration of the mpox outbreak in the Netherlands can be ascribed primarily to infection-induced immunity among MSM with high sexual activity levels. The decline was accelerated by behavioral adaptations. Immunity among those most sexually active is essential to impede mpox resurgence.
Optical fiber sensors in infrastructure monitoring: a comprehensive review
Authors: Chen Bangkuang , Zhu Zirui , Su Ziteng , Yao Wang , Zheng Shijie , Wang Ping 
Published: September 2023

Abstract
The purpose of this article is to review and further promote the application of optical fiber sensor technology in infrastructure monitoring. Compared with traditional sensors, optical fiber sensors have low maintenance costs and are small in size; consequently, they have gradually become a future development direction of sensors. This paper introduces the basic principles of several commonly used optical fiber sensors and the progress of optical fiber sensors in the monitoring of physical, mechanical, and chemical parameters and demonstrates the applications of optical fiber sensors in infrastructure.
Optimization of a Solid-Phase Extraction Coupled with a High-Performance Liquid Chromatography and Diode Array Ultraviolet Detection Method for Monitoring of Different Antibiotic Class Residues in Water Samples
Authors: Mahmoud Rania A , Hadad Ghada M , Abdel Salam Randa A , Mokhtar Hatem I 
Published: September 2023

Abstract

Background
The increased use of cephalosporin antibiotics in the last few years as well as the detection of their residues in wastewater treatment plants and hospital wastewater poses a risk for infiltration of their residues into environmental water samples.

Objective
A simplified, sensitive, and convenient solid-phase extraction (SPE) procedure coupled with either HPLC or fast HPLC methods with diode array detection was developed and validated to screen the residues of six different cephalosporin antibiotics: cefoperazone, cefipime, ceftazedime, ceftriaxone, cefdinir, and cefotaxime, along with amoxicillin, levofloxacin, and ciprofloxacin in water samples.

Methods
An HPLC–diode array detector (HPLC–DAD) method and a fast HPLC method, based on a core-shell stationary phase, were developed for the fast screening of the antibiotic compounds. In addition, the SPE step was optimized to enable the extraction of the studied drugs with high accuracy of the recovered amounts of residues.

Results
The method sensitivity was enhanced by the coupling of SPE with HPLC–DAD and fast HPLC to achieve low LODs; from 0.2 to 3.8 ng/mL and from 0.65 to 12.2 ng/mL, respectively. The developed methods were augmented by LC–MS/MS determination for confirmation of identity and quantity of any positively identified sample. The method was applied to the analysis of water samples collected from a rural site. In Addition, an example application of cleaning validation of cefotaxime-contaminated stainless-steel surfaces was provided.

Conclusion
The method’s simplicity and high sensitivity encourage its application in monitoring of antibiotic residues in different types of water samples such as environmental samples and samples from cleaning validation activities.

Highlights
HPLC–DAD and fast HPLC methods were developed for separation of nine different antibiotics. The combination with the SPE procedure achieved low detection limits; from 0.2 to 3.8 ng/mL for SPE–HPLC–DAD and from 0.65 to 12.2 ng/mL for SPE–fast HPLC.
Prevalence and potential evolutionary significance of color variants in freshwater crayfishes (Decapoda: Astacidea)
Authors: Graham Zackary A 
Published: September 2023

Abstract
Mutations may lead to the evolution and diversification of color phenotypes in animals. Much of the research on this topic, however, has been conducted on vertebrates. I compile here records of color variants in freshwater crayfishes (Decapoda: Astacidea). I found color variants to be surprisingly common, with 115 documented occurrences. The overwhelming majority of these variants were blue-colored (71.3%), although there are records of document red and orange variants, among others. Whether these variants are all due to mutations or can lead to adaptive evolution in crayfishes is unknown. Some crayfish species exhibit conspicuous colors like blue, orange, and red in nature. Many of these conspicuously colored species are also semi-terrestrial burrowers, which have limited migration potential, smaller population sizes, and thus reduced gene flow compared to aquatic burrowing crayfishes. I speculate that in at least some species, conspicuous colors may be a neutral color trait that faces little to no selective pressure. This is one potential explanation as to why semi-terrestrial burrowing species are more likely to be conspicuously colored. Genetic studies and behavioral experiments are required to test this hypothesis.
Seismic random noise attenuation using DnCNN with stratigraphic dip constraint
Authors: Yang Wei , Chen Xuehua , Rao Ying 
Published: September 2023

Abstract
In this paper, a method for seismic random noise detection and suppression using a denoising convolutional neural network (DnCNN) is presented. Thanks to the residual learning and batch normalization, deep learning networks can converge faster, the gradient descent and disappearance due to the increase of network layers are solved, and the residual results can be predicted more accurately. For seismic data, the variance estimation method is useful for obtaining an accurate noise distribution model and statistical parameters that provide a useful assessment of the noise level. With the variance estimation method based on weak texture blocks, a noise distribution model and statistical parameters can be derived with high accuracy, and this method effectively estimates seismic noise levels. The DnCNN networks are trained, and non-Gaussian noise reduction technology is used to achieve blind noise reduction at unknown levels, improving the noise reduction of seismic data. In addition, stratigraphic dip characteristics related to layer structure are used as DnCNN training network constraints to prevent effective signals in seismic data from being corrupted by conventional DnCNN noise reduction methods. Geological features such as faults and fracture-cavities can be effectively protected. Carbonate faults in the Tarim Basin in China are affected by the desert surface and the depth at which reservoirs are buried. The seismic data has a low signal-to-noise ratio, and the effective signals of the reservoir are low resolution. The seismic data can be effectively enhanced with this method for noise reduction in this area, the fracture-cavity is effectively displayed, and the fault features are also highlighted.
Exploring the Impact of Automation Bias and Complacency on Individual Criminal Responsibility for War Crimes
Authors: Coco Antonio 
Published: September 2023

Abstract
With advancing technology, complex decision-making in warfare, including targeting, is increasingly assisted by machines. Although involving humans in decision-making is often seen as a safeguard against machine errors, it does not always prevent them. Machines can make incorrect determinations or delay them when time is critical. In these cases, human operators, influenced by automation bias (excessive trust in machines’ determinations, despite the availability of contradicting or different information from other sources) or complacency (excessive trust in machines’ determinations, leading to reduced vigilance), may fail to recognize machine errors, potentially resulting in conduct amounting to a war crime. Considering the role of automation bias and complacency in the determination of the criminal responsibility of systems’ operators is crucial, especially, for understanding the accountability framework for war crimes involving autonomous weapon systems (AWS). By exploring how automation bias and complacency affect the determination of criminal responsibility for humans who operate AWS, this article offers insights for lawmakers at the national and international levels to understand complexities and effectively shape legislative responses with respect to criminal responsibility. This article also examines automation bias and complacency in psychology, their relevance in military operations employing AWS, and their potential to exonerate human operators from criminal responsibility. It concludes by advocating for legislative, organizational, and technical measures to counteract automation bias and complacency.
A rapid multiplex loop-mediated isothermal amplification (mLAMP) assay for detection of Entamoeba histolytica and Giardia duodenalis
Authors: Mewara Abhishek , Khunger Sandhya , Sharma Chayan , Krishnamoorthi Sivanantham , Singh Shreya , Yadav Rakesh , Khurana Sumeeta , Sehgal Rakesh 
Published: September 2023

Abstract
We developed a rapid multiplex loop-mediated isothermal amplification (mLAMP) assay for two common intestinal parasites—Entamoeba histolytica and Giardia duodenalis, where early detection may be helpful. The mLAMP assay was optimized for the detection of DNA of E. histolytica (18S rRNA gene) and G. duodenalis (Elongation factor 1 alpha gene) from standard strains by using six specific primers FIP (forward inner primer), BIP (backward inner primer), F3 (forward outer primer), B3 (backward outer primer), loopF (forward loop primer), and loopB (backward loop primer) for each gene target. The amplification time was 16–26 min for E. histolytica and 10–15 min for G. duodenalis, and the parasites could be distinguished based on melting-curve analysis for specific annealing temperatures (Tm) of 84°C–86°C and 88°C–90°C for E. histolytica and G. duodenalis, respectively. The analytical sensitivity was one fg, and no cross-reactivity with other intestinal pathogens was observed. Thus, the mLAMP assay could detect and clearly distinguish E. histolytica and G. duodenalis with a rapid turnaround time and excellent analytical sensitivity and specificity.
Influence of three parameters on maximum mass and stability of strange star under linear f(Q) − action
Authors: Lohakare Santosh V , Maurya S K , Singh Ksh Newton , Mishra B , Errehymy Abdelghani 
Published: September 2023

ABSTRACT
This study simulates strange stars in f(Q) gravity with an additional source under an electric field using gravitational decoupling by means of the complete geometric deformation (CGD) technique. By employing the Tolman ansatz and the MIT bag model equation of state (EOS), we explore bounded star configurations derived from the $\theta _0^0 = \rho$ and $\theta _1^1 = p_r$ sectors within the CGD formalism. Our models are subjected to physical viability tests, and we analyse the impact of anisotropy and the electric charge parameter E0 as well as the coupling parameters α and β1. Comparisons are made with observational constraints, including GW190814, neutron stars PSR J1614-2230, PSR J1903 + 6620, Cen X-3, and LMC X-4. Notably, we achieve the presence of a lower ‘mass gap’ component by adjusting parameters α and β1. Our models exhibit well-behaved mass profiles, internal regularity, and stability, along with the absence of gravitational collapse verified through the Buchdahl–Andréasson’s limit. In addition, we present a detailed physical analysis based on three parameters, α (decoupling strength), β1 (f(Q)–coupling), and Q (surface charge). This study provides insights into the behaviour of compact objects in f(Q) gravity and expands our understanding of strange star configurations within this framework.
Massive dark matter haloes at high redshift: implications for observations in the JWST era
Authors: Chen Yangyao , Mo H J , Wang Kai 
Published: September 2023

ABSTRACT
The presence of massive galaxies at high z as recently observed by JWST appears to contradict the current ΛCDM cosmology. Here, we aim to alleviate this tension by incorporating uncertainties from three sources in counting galaxies: cosmic variance, error in stellar mass estimation, and backsplash enhancement. Each of these factors significantly increases the cumulative stellar mass density ρ*(&gt;M*) at the high-mass end, and their combined effect can boost the density by more than one order of magnitude. Assuming a star formation efficiency of ϵ* ∼ 0.5, cosmic variance alone reduces the tension to a 2σ level, except for the most massive galaxy at z = 8. Additionally, incorporating a 0.3 dex lognormal dispersion in the stellar mass estimation brings the observed ρ*(&gt;M*) at z ∼ 7–10 within 2σ. The tension is completely eliminated when we account for the gas stripped from backsplash haloes. These results highlight the importance of fully modelling uncertainties when interpreting observational data of rare objects. We use the constrained simulation, ELUCID, to investigate the descendants of high-z massive galaxies. Our findings reveal that a significant portion of these galaxies ultimately resides in massive haloes at z = 0 with $M_{\rm halo} \gt 10^{13}\, h^{-1}{\rm M_\odot }$. Moreover, a large fraction of local central galaxies in $M_{\rm halo} \geqslant 10^{14.5} \, h^{-1}{\rm M_\odot }$ haloes are predicted to contain substantial amounts of ancient stars formed in massive galaxies at z ∼ 8. This prediction can be tested by studying the structure and stellar population of central galaxies in present-day massive clusters.
Glass-like random catalogues for two-point estimates on the light-cone
Authors: Schulz Sebastian 
Published: September 2023

ABSTRACT
We introduce grlic, a publicly available Python tool for generating glass-like point distributions with a radial density profile n(r) as it is observed in large-scale surveys of galaxy distributions on the past light-cone. Utilizing these glass-like catalogues, we assess the bias and variance of the Landy–Szalay (LS) estimator of the first three two-point correlation function (2PCF) multipoles in halo and particle catalogues created with the cosmological N-body code gevolution. Our results demonstrate that the LS estimator calculated with the glass-like catalogues is biased by less than 10−4 with respect to the estimate derived from Poisson-sampled random catalogues, for all multipoles considered and on all but the smallest scales. Additionally, the estimates derived from glass-like catalogues exhibit significantly smaller standard deviation σ than estimates based on commonly used Poisson-sampled random catalogues of comparable size. The standard deviation of the estimate depends on a power of the number of objects NR in the random catalogue; we find a power law $\sigma \propto N_\mathit{R}^{-0.9}$ for glass-like catalogues as opposed to $\sigma \propto N_\mathit{R}^{-0.48}$ using Poisson-sampled random catalogues. Given a required precision, this allows for a much reduced number of objects in the glass-like catalogues used for the LS estimate of the 2PCF multipoles, significantly reducing the computational costs of each estimate.
Statistics of pressure fluctuations in turbulent kinetic plasmas
Authors: Adhikari S , Matthaeus W H , Parashar T N , Shay M A , Cassak P A 
Published: September 2023

ABSTRACTIn this study, we explore the statistics of pressure fluctuations in kinetic collisionless turbulence. A 2.5D kinetic particle-in-cell simulation of decaying turbulence is used to investigate pressure balance via the evolution of thermal and magnetic pressure in a plasma with β of order unity. We also discuss the behaviour of thermal, magnetic, and total pressure structure functions and their corresponding wavenumber spectra. The total pressure spectrum exhibits a slope of −7/3 extending for about a decade in the ion-inertial range. In contrast, shallower −5/3 spectra are characteristic of the magnetic pressure and thermal pressure. The steeper total pressure spectrum is a consequence of cancellation caused by density-magnetic field magnitude anti-correlation. Further, we evaluate higher order total pressure structure functions in an effort to discuss intermittency and compare the power exponents with higher order structure functions of velocity and magnetic fluctuations. Finally, applications to astrophysical systems are also discussed.
Can envelope backwarming of discs explain mm-bright, extended protostellar structures?
Authors: Han Fiona , Hartmann Lee , Calvet Nuria , Franco-Hernández Ramiro 
Published: September 2023

ABSTRACT
We construct simple models to explore in principle whether the backwarming by radiation from infalling envelopes can significantly heat and change the structure of protoplanetary discs. The motivation for this investigation is the recent study of a small subset of Orion protostars by Karnath et al., who argued that the bright, extended, and irregular sub-mm and mm emission did not arise from protostellar discs because the images were not elongated as expected. We therefore constructed simple disc models to see whether heating from the envelope surrounding a disc could in principle significantly increase disc scale heights and thus produce less-elongated images. We assume steady accretion and solve the radiative transfer self-consistently. For central luminosities and envelopes roughly comparable to the Karnath et al. protostars, we find that while envelope irradiation can significantly heat the discs, the magnitude of the effect only increases scale heights by modest factors, and so our models cannot easily account for the observed morphologies. We speculate that dynamical perturbations by companion protostars might be responsible for the observed complex structure.
Hydrodynamical simulations of circumbinary accretion: balance between heating and cooling
Authors: Wang Hai-Yang , Bai Xue-Ning , Lai Dong , Lin Douglas N C 
Published: September 2023

ABSTRACT
Hydrodynamical interaction in circumbinary discs (CBDs) plays a crucial role in various astrophysical systems, ranging from young stellar binaries to supermassive black hole binaries in galactic centres. Most previous simulations of binary-disc systems have adopted locally isothermal equation of state. In this study, we use the grid-based code Athena++ to conduct a suite of two-dimensional viscous hydrodynamical simulations of circumbinary accretion on a Cartesian grid, resolving the central cavity of the binary. The gas thermodynamics is treated by thermal relaxation towards an equilibrium temperature (based on the constant − β cooling ansatz, where β is the cooling time in units of the local Keplerian time). Focusing on equal mass, circular binaries in CBDs with (equilibrium) disc aspect ratio H/R = 0.1, we find that the cooling of the disc gas significantly influences the binary orbital evolution, accretion variability, and CBD morphology, and the effect depends sensitively on the disc viscosity prescriptions. When adopting a constant kinematic viscosity, a finite cooling time (β ≳ 0.1) leads to a binary inspiral as opposed to an outspiral and the CBD cavity becomes more symmetric. When adopting a dynamically varying α-viscosity, binary inspiral only occurs within a narrow range of cooling time (corresponding to β around 0.5).