bluuebunny/crossref_metadata_2025_split huggingface dataset:
Structuring reconstructions: recognising the advantages of interdisciplinary data in methodical research
Authors: Malcolm-Davies Jane 
Published: August 2023

Abstract
A theoretical framework for reconstruction as an integrated scholarly research method across a range of disciplines is long overdue. This paper discusses the usefulness of reconstructed textiles and dress as a template for it. It also argues that there is a need to integrate methods from the arts and humanities with analytical techniques from the natural sciences. The aim is to show how interdisciplinary research not only enriches a reconstruction but provides the mechanism through which cross-disciplinary collaboration takes place. Experimental remaking of historical textiles and dress has tended to be undertaken on an ad hoc basis. For reconstruction to be scientific, it must systematically employ soundly researched evidence from a variety of sources. The triangulation of data—well established in natural and social science—rigorously cross references primary evidence using a range of investigative methods. It produces a firm fix on the material under scrutiny and more credible results than those reliant on only one or two sources. The challenge is that different types of evidence demand specialist approaches, including quantitative and qualitative methods, which are not the traditional tools of dress history. Accurate reconstruction also demands interdisciplinary collaboration: the interrogation of fibres at the molecular level; the collection of observational data at the micro level; and the study of how garments were made and worn at the macro level. This calls for new ways of working with integrated methodologies in pragmatic multidisciplinary teams, which include experts from the humanities, sciences and craft.
Male sex is an independent risk factor for patellar osteochondral fractures following acute patellar dislocation in pediatric patients
Authors: Retzky Julia S. , Uppstrom Tyler J. , Chipman Danielle E. , Bovonratwet Patawut , Green Daniel W. 
Published: August 2023

AbstractPurposeAlthough most patellar dislocations are associated with medial patellofemoral ligament (MPFL) injury, many patients also sustain concomitant patellar osteochondral fractures following a patellar dislocation. Few prior studies have described or evaluated risk factors for patellar osteochondral fractures in pediatric patients. The purpose of the present study was to describe the incidenceand location of patellar osteochondral fractures following acute patellar dislocation in pediatric patients. In addition, we described risk factors for patellar osteochondral fractures in this population. We hypothesized that most fractures would occur at the inferomedial quadrant of the patella following a traumatic injury mechanism.MethodsFollowing Institutional Review Board approval, the electronic medical record was queried to identify pediatric patients ≤ 18 years old who underwent MPFL reconstruction (MPFLR) or non‐operative treatment for patellar instability between July 2016 and February 2020. Osteochondral fractures were defined as full‐thickness chondral injuries with attached subchondral bone or purely osseous injuries measuring ≥ 3 mm (mm) in at least two magnetic resonance imaging (MRI) planes. Patients were included in the study if they had complete preoperative x‐ray and MRI studies with minimum 6‐month follow‐up. Patients were excluded if they had incomplete imaging, isolated chondral fractures, or less than 6 months follow‐up. Univariate analysis was used to identify patient factors associated with osteochondral fractures. Multivariate regression analysis was used to identify risk factors for osteochondral fractures.ResultsSixty patients (63 knees) were included in the study, 15 (23.8%) of whom had a patellar osteochondral fracture. The majority of osteochondral fractures (87%) involved the inferomedial quadrant of the patella. Univariate analysis showed an association between male sex (p = 0.041), skeletal immaturity (p = 0.028), and decreased patellar tilt (p = 0.021) and patellar osteochondral fractures. Multivariate regression analysis identified male sex as an independent risk factor for osteochondral fractures (relative risk: 4.8, 95% confidence interval [CI]: 1.08–20.9, p = 0.039). No patients had recurrent dislocation at minimum 6‐month follow‐up. All patients with osteochondral fractures returned to sports at most recent follow up.ConclusionIn this study, 23% of pediatric patients with acute patellar dislocations have a concomitant patellar osteochondral fracture. The majority of patellar osteochondral fractures involve the inferomedial quadrant of the patella. Male sex is an independent risk factor for patellar osteochondral fractures, and skeletal immaturity is associated with patellar osteochondral fractures in this population.Level of evidenceLevel III.
The FLY-project: study protocol for mixed methods research to explore the complex social dynamics of sustainable food-related lifestyles in youth in practical education
Authors: van Etten Soraya , Jansen Lonneke , Bal Michèlle , Dermody Brian J. , Müller Eggo , de Wit John , Stok Marijn 
Published: August 2023

Abstract
Background
The present-day food system is a key driver of climate change and biodiversity loss, making it imperative for populations to shift towards more sustainable diets. The involvement of youth in this transition is vital because they are in a formative period where their identities, values, and norms, including their food behaviours, are being shaped. Special attention should be paid to youth in practical education because they are often overlooked in existing studies, yet evidence suggests they may lack the necessary resources to support dietary changes, resulting in lower levels of pro-environmental food-related behaviours. The aim of the FLY (Food-related Lifestyles in Youth) project is to study how sustainable food-related lifestyles and underlying factors develop in early adolescence, particularly in Dutch youth in practical education, how these spread in social networks, and to develop community-level intervention strategies to support youths’ transition to sustainable food-related behaviours.

Methods/design
The FLY-project adopts a mixed-method approach. First, two literature reviews are conducted. A systematic review assesses how capabilities, opportunities and motivation are associated with sustainable food behaviours in youth, and how these elements interrelate in determining sustainable food-related lifestyles. A scoping review studies community-level interventions that target sustainable and healthy food-related behaviours. Second, focus groups are conducted to explore the barriers and facilitating factors concerning capabilities, opportunities, and motivations that Dutch youth in practical-level education experience to transition to more sustainable food-related lifestyles. Third, a cohort survey study is conducted to track the dynamic interplay between capabilities, opportunities, motivation, and changes in specific sustainable food behaviours over time, and to assess the diffusion of sustainable food-related lifestyles via social (media) networks. Fourth, an experimental research programme tests promising intervention approaches, some of which are co-created with youth, targeting relevant underlying factors.

Discussion
This paper describes the rationale, conceptual framework, design and methods of the FLY-project. The FLY-project contributes to an understanding of underlying factors of sustainable food-related behaviours in adolescence and results in a multi-component intervention toolkit, with a particular focus on youth in practical education programmes.
Usefulness of intraoperative transesophageal echocardiography for hemodynamic management of liver transplantation in a patient with massive polycystic liver disease: a case report
Authors: Ueda Yudai , Kawaji Takahiro , Komura Hidefumi , Hara Yoshitaka , Kuriyama Naohide , Nakamura Tomoyuki , Nishida Osamu 
Published: August 2023

Abstract
Background
Hemodynamic management during anesthesia in liver transplantation for patients with polycystic liver disease (PLD) can be more challenging because of the bleeding and hemodynamic alterations due to the markedly enlarged liver. We hereby report a case of PLD wherein transesophageal echocardiography (TEE) was employed for optimal hemodynamic monitoring during liver transplantation.

Case presentation
A 61-year-old man was scheduled to undergo liver transplantation for massive PLD. Hemodynamic instability was associated with mechanical displacement of the giant cystic liver. TEE results revealed the collapse of the inferior vena cava due to liver displacement. TEE also detected intrathoracic hemorrhage triggered by detachment from the markedly enlarged liver.

Conclusion
TEE is a valuable monitoring tool for sharing information with surgeons and diagnostic modality for finding the source of bleeding in liver transplantation for PLD and may contribute majorly to the quality of perioperative management.
Association of angiotensin-converting enzyme I/D polymorphism and apolipoprotein B with cardiometabolic abnormalities among young adults: a pilot study from Delhi
Authors: Suokhrie Seyielenuo , Chaudhary Vineet , Mishra Sumit , Murry Benrithung , Devi Naorem Kiranmala 
Published: August 2023

Abstract
Background
Angiotensin-converting enzyme (ACE) gene polymorphism and elevated apolipoprotein B (apoB) are important risk factors for several cardiometabolic abnormalities. However, much less attention has been given to the relationship between these risk factors and cardiometabolic abnormalities among young adults. Considering this gap, the present study explored the association of ACE I/D polymorphism and apoB with cardiometabolic abnormalities among young adults of Delhi, India.

Methods
This cross-sectional study was conducted among young adults (aged 18–30) of either sex residing in Delhi, India. A total of 330 individuals were invited to participate in the study, and data on the socio-demographic variables were collected using a pre-tested interview schedule. Somatometric and physiological measurements were obtained using standard protocols. However, blood sample collection and biochemical and genetic analyses could successfully be performed for 178 individuals. Fasting blood glucose (FBG), total cholesterol (TC), triglyceride (TG), high-density lipoprotein (HDL), and low-density lipoprotein (LDL) levels were estimated using Erba XL-640 biochemical analyzer. LDL and TG values were used to calculate apoB levels. Genotyping for ACE I/D polymorphism was performed by allele-specific PCR amplification followed by electrophoresis. Statistical analysis was done using SPSS v.20.

Results
ACE I/D polymorphism was not found to be associated with hypertension, obesity, and abnormal FBG, TG, and HDL levels. However, DD and ID genotypes and D allele, with II as the reference genotype, significantly reduced the risk for high TC (OR, p value = 0.14, 0.01*; 0.29, 0.04*; 0.22, < 0.01*, respectively) and high LDL (OR, p value = 0.17, 0.03*; 0.20, 0.03*; 0.19, < 0.01*, respectively). Except for abnormal FBG, the prevalence of all the studied cardiometabolic abnormalities was significantly higher in the 4th quartile of apoB when compared to other quartiles. Linear regression model revealed a significant positive association of apoB levels with diastolic blood pressure, studied obesity parameters, TC, TG, and LDL levels.

Conclusion
The D allele of ACE I/D polymorphism was not associated with most of the studied cardiometabolic abnormalities in the present study. Further, the association of high apoB with cardiometabolic abnormalities hints toward the importance of apoB in the early diagnosis of CVDs.
Accuracy and Survival Outcomes after National Implementation of Sentinel Lymph Node Biopsy in Early Stage Endometrial Cancer
Authors: Cabrera Silvia , Gómez-Hidalgo Natalia R. , García-Pineda Virginia , Bebia Vicente , Fernández-González Sergi , Alonso Paula , Rodríguez-Gómez Tomás , Fusté Pere , Gracia-Segovia Myriam , Lorenzo Cristina , Chacon Enrique , Roldan Rivas Fernando , Arencibia Octavio , Martí Edo Marina , Fidalgo Soledad , Sanchis Josep , Padilla-Iserte Pablo , Pantoja-Garrido Manuel , Martínez Sergio , Peiró Ricard , Escayola Cecilia , Oliver-Pérez M. Reyes , Aghababyan Cristina , Tauste Carmen , Morales Sara , Torrent Anna , Utrilla-Layna Jesus , Fargas Francesc , Calvo Ana , Aller de Pace Laura , Gil-Moreno Antonio ,   on behalf of the Spain-GOG and the MULTISENT Study Group
Published: August 2023

Abstract
Background
Sentinel lymph node (SLN) biopsy has recently been accepted to evaluate nodal status in endometrial cancer at early stage, which is key to tailoring adjuvant treatments. Our aim was to evaluate the national implementation of SLN biopsy in terms of accuracy to detect nodal disease in a clinical setting and oncologic outcomes according to the volume of nodal disease.

Patients and Methods
A total of 29 Spanish centers participated in this retrospective, multicenter registry including patients with endometrial adenocarcinoma at preoperative early stage who had undergone SLN biopsy between 2015 and 2021. Each center collected data regarding demographic, clinical, histologic, therapeutic, and survival characteristics.

Results
A total of 892 patients were enrolled. After the surgery, 12.9% were suprastaged to FIGO 2009 stages III–IV and 108 patients (12.1%) had nodal involvement: 54.6% macrometastasis, 22.2% micrometastases, and 23.1% isolated tumor cells (ITC). Sensitivity of SLN biopsy was 93.7% and false negative rate was 6.2%. After a median follow up of 1.81 years, overall surivial and disease-free survival were significantly lower in patients who had macrometastases when compared with patients with negative nodes, micrometastases or ITC.

Conclusions
In our nationwide cohort we obtained high sensitivity of SLN biopsy to detect nodal disease. The oncologic outcomes of patients with negative nodes and low-volume disease were similar after tailoring adjuvant treatments. In total, 22% of patients with macrometastasis and 50% of patients with micrometastasis were at low risk of nodal metastasis according to their preoperative risk factors, revealing the importance of SLN biopsy in the surgical management of patients with early stage EC.
Brugada syndrome is still a current clinical problem. What do we know today - a literature review
Authors: Misiło Adriana , Sosna Monika , Mordoń Krzysztof 
Published: August 2023

Brugada syndrome (BrS) is a rare congenital arrhythmia syndrome. BrS is characterized by a tendency to syncope, ventricular arrhythmias and sudden cardiac death. These symptoms occur mainly at night and can occur spontaneously or as a result of provocation by, for example, fever, stress or medication. Based on the differences in electrocardiography, three types were distinguished. Genetic studies are being conducted, which have shown a significant defect of the SCN5A gene, which in turn leads to disturbances in the functioning of the sodium channel NaV1.5 has a negative impact on the course of depolarization of myocardial cells. Patients with symptoms of the disease are subjected to implantation of a cardioverter-defibrillator, which protects them against sudden death. Data was obtained from the PubMed and Google Scholar platforms.
Cutaneous recurrence of long term pulmonary sarcoidosis - literature review and case report
Authors: Bargieł Julia , Cabaj Justyna , Chmielewska Izabela , Adamczyk-Korbel Marta , Grzywa-Celińska Anna 
Published: August 2023

Sarcoidosis is a systemic granulomatous disease, the exact etiology of which is unknown. This paper presents a case of a patient with a long course of pulmonary sarcoidosis with exacerbation of the disease in the form of skin lesions.
A 50-year-old female patient was admitted to the Department of Tuberculosis and Lung Diseases, Medical University of Lublin, because of cervical lymphadenopathy. Based on the histopathological examination, she was diagnosed with sarcoidosis. The patient reported constant fatigue, throat tightness and difficulty swallowing, as well as decreased exercise tolerance. Computed tomography studies revealed small nodular changes in both lungs and mediastinal lymphadenopathy. The patient was actively monitored. The results of spirometry tests improved spontaneously and remained at a satisfactory level for years. After 15 years of follow-up, the patient reported skin lesions that are constantly progressing. Examination of the cut from the skin lesion confirmed skin sarcoidosis.
This case report highlights the varied course of sarcoidosis, which, as a multi-system disease, may show various manifestations. In clinical practice, therefore, one should consider the possibility of disease progression and transmission to multiple organs. It is important that the patient is under constant observation and that new lesions undergo differential diagnosis and histopathological examination.
Depression - the first symptom of a brain tumor or a consequence of the process neoplastic process - a review of the literature
Authors: Antkowiak Klaudia , Ciecierski-Koźlarek Hubert , Żurek Urszula , Tołwiński Ignacy , Kędzierska Zofia , Dadas Klaudia , Świercz Aleksandra , Małachowska Dominika , Shved Kateryna 
Published: August 2023

Introduction and objective
CNS malignancies account for about 1.6% of all diseases today. In people diagnosed with abrain tumor with a poor prognosis, we often see disorders from the psychiatric spectrum,most often depressive disorders. In this paper, we want to focus on whether depression occursas a sequel to cancer or perhaps is the first of the symptoms of a CNS tumor.
Review methods
For the analysis, the PubMed medical database was searched, and articles containing studiesand case reports of people with CNS tumor and depressive disorders that occurred eitherbefore diagnosis or at any time during the course of the disease were selected
Abbreviated description of the state of knowledge
CNS tumors produce symptoms such as epilepsy, visual disturbances, paresis, but alsobehavioral disorders. This is determined by the location of the tumor. Depression is a mentaldisorder manifested mainly by lowered mood. This disorder can coexist with tumorsoccurring in the frontal lobe or be present regardless of the location of the tumor, in peoplediagnosed with a tumor with a poor prognosis.
Summary
Analyzing the selected articles, we see that in people who were diagnosed with a tumorlocated in the frontal lobe, often the first symptom was depressive disorders, which evenpreceded neurological symptoms. When depression is diagnosed, appearing suddenly andrefractory to treatment, one should consider whether there is an underlying pathologicallesion in the CNS. Unfortunately, there are no specific guidelines for imaging studies indepressive disorders. People who suffer from malignant tumors with a poor prognosis shouldbe cared for by a psychologist, because as the disease progresses, the symptoms worsen,affecting the prognosis.
The tobacco epidemic – pharmacological interventions for smoking cessation
Authors: Sergiel Natalia , Maj Patrycja , Włodarczyk-Cybulska Karolina , Kania Agata , Gonet Malwina , Miszczyk Karolina , Serwik-Trandasir Aleksandra , Mozer Piotr , Maternia Jakub , Lazar Michał 
Published: August 2023

Introduction: One of the biggest public health threats in the world is tobacco epidemic. According to WHO in the world cigarette smoking is the most common form of tobacco use. In the 2018 report of the World Health Organization (WHO), smoking was recognized as one of the main risk factors responsible for premature mortality due to non-communicable diseases. According to the Global Burden of Disease, estimates smoking causes almost 8 million deaths in 2019 worldwide. In Poland about one-quarter of adults smoke cigarettes. As a result, scientists are constantly looking for medications that could help people quit smoking.
The aim of the study: The aim of our study is to present medication which are used for treating nicotine dependence nowadays. Moreover, we give attention to social and economic consequences of tobacco use.
Materials and methods: The literature available on PubMed and Google Scholar was reviewed using the words: “smoking”, “smoking cessation”, “nicotine”, “nicotine replacement therapy”.
Description of the state of knowledge: Exposure to tobacco smoke is a dominant factor in the incidence of many cancers as well as cardiovascular and respiratory diseases. Therefore, improving smoking cessation interventions is critical to reducing tobacco use and helping to minimize the burden of cancer and other diseases for example chronic obstructive pulmonary disease.
Conclusions: Smoking cessation has a positive effect on health. Nicotine replacement therapy, Bupropion, Varenicline and Cytisine are used to reduce nicotine withdrawal symptoms in regular smokers who abstain from smoking.
Conventional and biological therapies in atopic dermatitis – a literature review
Authors: Włodarczyk-Cybulska Karolina , Sergiel Natalia , Maj Patrycja , Mozer Piotr , Maternia Jakub , Lazar Michał , Kania Agata , Serwik-Trandasir Aleksandra , Gonet Malwina , Miszczyk Karolina 
Published: August 2023

Introduction: Atopic dermatitis is a chronic, relapsing disease with a multifactoral etiology. The basic disorder of the atopic dermatitis is the disruption of the epidermal barrier. The family history of atopy is a high risk factor of the development of the disease. The clinical manifestations are heterogeneous and vary depending on patient’s age, disease duration and current disease activity according to the SCORAD scale.

Objective: The aim of the review is to analyze the latest information on the characteristics, diagnosis and treatment of atopic dermatitis, including new biological medications.

Methods and materials: The sources available in PubMed database have been analyzed using the keywords: „atopic dermatitis”, „epidermal barrier”, „SCORAD index”, „topical treatment”, „biological therapy”, „Janus kinase inhibitors”.

Current state of knowledge: Atopic dermatitis is only treated symptomatically. The greatest therapeutic challenge is to reduce the pruritus which significantly impairs the quality of life. Topical corticosteroids may cause local side effects. The most severe cases of the disease require systemic treatment with immunosuppressants.

Conclusions: The complex pathogenesis of atopic dermatitis is the object of research. Understanding the immunological mechanisms responsible for the development of the disease allows to introduce new therapeutic options. Previous studies have confirmed the effectiveness of biological medications in reducing disease activity, which is a chance to improve the quality of live of the patients suffering from atopic dermatitis.