bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative study of different lithium salts as electrolyte additives of Li/SiOx–Si–C half-cells for lithium sulfur batteries
Authors: Mathew Deepa Elizabeth , Dhanalakshmi R. Baby , Sathya S. , Kathiresan M. , Thomas Sabu , Alkordi Mohamed H. , Stephan A. Manuel 
Published: July 2023

AbstractSilicon oxide and its derivatives (SiOx, 0 < x < 2) are drawing significant interest as electrode material for Li-ion and Li–S batteries owing to their unique properties of high specific capacity, low working potential, high abundance, and environmental friendliness. In-depth research is done on the effects of electrolyte additives on the electrochemical and interfacial characteristics of SiOx-based anodes for Li–S batteries. Two different electrolyte additives namely lithium bis (fluorosulfonyl imide) (LiFSI) and lithium bis (oxalatoborate) (LiBOB) were incorporated in the supporting electrolyte containing 1 M lithium bis (trifluoromethanesulfonyl imide) (LiTFSI) in tetraethylene glycol dimethyl ether (TEGDME): 1,3 dioxolane (DOL) in the ratio of 1:1 (v/v). The Li/SiOx–Si–C 2032-type half-cells were assembled, and their charge–discharge properties were explored at 0.1 C-rate. Surface morphology and electrochemical impedance investigations of the electrode materials have been performed after cycling. The interfacial properties of SiOx-based electrodes were examined by FTIR and XPS. Among the electrolytes studied LiFSI-added electrolytes offer superior charge–discharge properties, which was attributed to the formation of a stable solid electrolyte interphase (SEI) layer on the electrode surface. The surface chemistry studies revealed the formation of Li2CO3 and ROCO2Li peaks on the lithium metal surface. The formation of Li2CO3 and ROCO2Li compounds are identified on lithium surface by XPS data and complemented by NMR analysis.
Distinction between low-barrier hydrogen bond and ordinary hydrogen bond: a case study of varying nature of charge assisted hydrogen bonds of diglycine perchlorate crystal
Authors: Choudhury Rajul Ranjan , Chitra R , Panicker Lata 
Published: July 2023

Abstract
Hydrogen bonding is a complex phenomenon that is a resultant of many energy components like the electrostatic, dispersive, covalent, charge cloud overlap repulsion etc, nature of hydrogen bond (H-bond) depends on which of these components play a dominant role. Low barrier hydrogen bond (LBHB) constitutes a special category of hydrogen bonds characterized by near delocalization of proton between donor and acceptor groups of the H- bond unlike an ordinary hydrogen bond (OHB) having proton clearly localized near the donor group. The significance of LBHBs in macromolecular interactions has been highly controversial, despite may attempts the existence and potential importance of protein LBHBs remains debatable. In order to answer questions like whether or not a distinct class of LBHBs exists and if they do exist under what conditions they are formed and how do they behave differently from OHBs, a detailed study of H-bonding in Diglycine Perchlorate (DGPCl) crystal containing five unique hydrogen bonded glycinium-glycine pairs is undertaken. All O-H–O bonds of DGPCl are between the carboxyl (-COOH) and carboxylate (-COO−) groups with slightly different electron distributions resulting in observable variations in the H-bond geometries, this is an indication of varying strength of these short strong H-bonds. It is found that LBHB nature of the five O-H—O bonds between glycinium-glycine pairs (P1-P5) varies as P1 < P4 < P2 < P3 < P5. This study gives an experimental evidence of the existence of LBHBs and demonstrates that the behaviour of LBHBs is very different from that of strong OHBs.
Protection Without Discrimination
Authors: Rebeyrol Vincent 
Published: July 2023

Abstract
This paper shows that non-tariff measures may fully respect the non-discrimination principle of the World Trade Organisation and still act as a protectionist device. Non-tariff measures that raise costs of all firms induce some exit, reallocating market shares towards the most efficient firms. The paper analyses when this mechanism generates protectionism. With political economy motives, trade liberalisation increases the use of non-tariff measures in the non-cooperative equilibrium and a trade agreement may be welfare reducing if governments care about the most efficient firms only. Moreover, a Pareto improving agreement may require an income redistribution between countries if firm average productivity differs across countries.
A new haplotype-resolved turkey genome to enable turkey genetics and genomics research
Authors: Barros Carolina P , Derks Martijn F L , Mohr Jeff , Wood Benjamin J , Crooijmans Richard P M A , Megens Hendrik-Jan , Bink Marco C A M , Groenen Martien A M 
Published: July 2023

Abstract

Background
The domesticated turkey (Meleagris gallopavo) is a species of significant agricultural importance and is the second largest contributor, behind broiler chickens, to world poultry meat production. The previous genome is of draft quality and partly based on the chicken (Gallus gallus) genome. A high-quality reference genome of M. gallopavo is essential for turkey genomics and genetics research and the breeding industry.

Results
By adopting the trio-binning approach, we were able to assemble a high-quality chromosome-level F1 assembly and 2 parental haplotype assemblies, leveraging long-read technologies and genome-wide chromatin interaction data (Hi-C). From a total of 40 chromosomes (2n = 80), we captured 35 chromosomes in a single scaffold, showing much improved genome completeness and continuity compared to the old assembly build. The 3 assemblies are of higher quality than the previous draft quality assembly and comparable to the chicken assemblies (GRCg7) shown by the largest contig N50 (26.6 Mb) and comparable BUSCO gene set completeness scores (96–97%). Comparative analyses confirm a previously identified large inversion of around 19 Mbp on the Z chromosome not found in other Galliformes. Structural variation between the parent haplotypes was identified, which poses potential new target genes for breeding.

Conclusions
We contribute a new high-quality turkey genome at the chromosome level, benefiting turkey genetics and other avian genomics research as well as the turkey breeding industry.
Jujube witches’ broom phytoplasmas inhibit ZjBRC1-mediated abscisic acid metabolism to induce shoot proliferation
Authors: Ma Fuli , Zhang Shanqi , Yao Yu , Chen Mengting , Zhang Ning , Deng Mingsheng , Chen Wei , Ma Chi , Zhang Xinyue , Guo Chenglong , Huang Xiang , Zhang Zhenyuan , Li Yamei , Li Tingyi , Zhou Junyong , Sun Qibao , Sun Jun 
Published: July 2023

Abstract
Jujube witches’ broom (JWB) phytoplasmas parasitize the sieve tubes of diseased phloem and cause an excessive proliferation of axillary shoots from dormant lateral buds to favour their transmission. In previous research, two JWB effectors, SJP1 and SJP2, were identified to induce lateral bud outgrowth by disrupting ZjBRC1-mediated auxin flux. However, the pathogenesis of JWB disease remains largely unknown. Here, tissue-specific transcriptional reprogramming was examined to gain insight into the genetic mechanisms acting inside jujube lateral buds under JWB phytoplasma infection. JWB phytoplasmas modulated a series of plant signalling networks involved in lateral bud development and defence, including auxin, abscisic acid (ABA), ethylene, jasmonic acid, and salicylic acid. JWB-induced bud outgrowth was accompanied by downregulation of ABA synthesis within lateral buds. ABA application rescued the bushy appearances of transgenic Arabidopsis overexpressing SJP1 and SJP2 in Col-0 and ZjBRC1 in the brc1-2 mutant. Furthermore, the expression of ZjBRC1 and ABA-related genes ZjHB40 and ZjNCED3 was negatively correlated with lateral main bud outgrowth in decapitated healthy jujube. Molecular evidence showed that ZjBRC1 interacted with ZjBRC2 via its N-terminus to activate ZjHB40 and ZjNCED3 expression and ABA accumulation in transgenic jujube calli. In addition, ZjBRC1 widely regulated differentially expressed genes related to ABA homeostasis and ABA signalling, especially by binding to and suppressing ABA receptors. Therefore, these results suggest that JWB phytoplasmas hijack the ZjBRC1-mediated ABA pathways to stimulate lateral bud outgrowth and expansion, providing a strategy to engineer plants resistant to JWB phytoplasma disease and regulate woody plant architecture to promote crop yield and quality.
Proteomic analysis revealed the function of PoElp3 in development, pathogenicity, and autophagy through the tRNA-mediated translation efficiency in the rice blast fungus
Authors: Liu Yuanhao , Sun Ting , Li Yuyong , Huang Jianqiang , Wang Xianjun , Bai Huimin , Hu Jiayi , Zhang Zifan , Wang Shuai , Zhang Dongmei , Li Xiuxiu , Wang Zonghua , Zheng Huakun , Lin Guifang 
Published: July 2023

AbstractThe Elongator complex is conserved in a wide range of species and plays crucial roles in diverse cellular processes. We have previously shown that the Elongator protein PoELp3 was involved in the asexual development, pathogenicity, and autophagy of the rice blast fungus. In this study, we further revealed that PoElp3 functions via tRNA-mediated protein integrity. Phenotypic analyses revealed that overexpression of two of the tRNAs, tK(UUU) and tQ(UUG) could rescue the defects in ΔPoelp3strain. TMT-based proteomic and transcriptional analyses demonstrated that 386 proteins were down-regulated in ΔPoelp3strain compared with wild type strain Guy11, in a transcription-independent manner. Codon usage assays revealed an enrichment of Glutamine CAA-biased mRNA in the 386 proteins compared with the 70-15 genome. In addition to those reported previously, we also found that PoErp9, a sphingolipid C9-methyltransferase, was down-regulated in the ΔPoelp3strain. Through anILV2-specific integration ofPoERP9-GFPinto the wild type and ΔPoelp3strain, we were able to show that PoErp9 was positively regulated by PoElp3 translationally but not transcriptionally. Functional analyses revealed that PoErp9 was involved in the fungal growth, conidial development, pathogenicity, and TOR-related autophagy homeostasis inP. oryzae. Taken together, our results suggested that PoElp3 acts through the tRNA-mediated translational efficiency to regulate asexual development, pathogenicity, and autophagy in the rice blast fungus.
Coping with abnormal organizational behaviors in complex project based on network attack theory
Authors: Yang Lin , Lv Xiaoyue , Zhao Xianbo 
Published: July 2023

PurposeAbnormal behaviors such as rework, backlog, changes and claims generated by project organizations are unavoidable in complex projects. When abnormal behaviors emerge, the previously normal state of interactions between organizations will be altered to some extent. However, previous studies have ignored the associations and interactions between organizations in the context of abnormal organizational behaviors (AOBs), making this challenging to cope with AOBs. As a result, the objective of this paper is to explore how to reduce AOBs in complex projects at the organizational level from a network perspective.Design/methodology/approachTo overcome the inherent limitations of a single case study, this research integrated two data collection methods: questionnaire survey and expert scoring method. The questionnaire survey captured the universal data on the influence possibility of AOBs between complex project organizations and the expert scoring method got the influence probability scores of AOBs between organizations in the case. Using these data, four organizational influence network models of AOBs based on a case were developed to demonstrate how to destroy AOBs networks in complex projects using network attack theory (NAT).FindingsFirst, the findings show that controlling AOBs generated by key organizations preferentially and improving the ability of key organizations can weaken AOBs network, enabling more effective coping strategies. Second, the owners, government, material suppliers and designers are identified as key organizations across all four influence networks of AOBs. Third, change and claim behaviors are more manageable from the organizational level.Practical implicationsProject managers can target specific organizations for intervention, weaken the AOBs network by applying NAT and achieve better project outcomes through coping strategies. Additionally, by taking a network perspective, this research provides a novel approach to comprehending the associations and interactions between organizations in the context of complex projects.Originality/valueThis paper proposes a new approach to investigating AOBs in complex projects by simultaneously examining rework, backlog, change and claim. Leveraging NAT as a novel tool for managing the harmful effects of influence networks, this study extends the knowledge body in the field of organizational behavior (OB) management and complex project management.
Drivers of China’s outward foreign direct investment: a comprehensive panel data analysis
Authors: Tong Tong , Singh Tarlok , Li Bin , Liu Lewis 
Published: July 2023

Purpose
This paper aims to investigate the primary motivations for China’s outward foreign direct investment (ODI) decisions.

Design/methodology/approach
Using a panel data sample covering the period 2003–2012 and a comprehensive set of 176 host countries.

Findings
This study finds that market size, trade variables and natural resource variables are strongly related to the Chinese ODI stocks. This indicates that Chinese ODI decisions are driven by both market- and resource-seeking motives. The subperiod sample test results lend even stronger support to the market-seeking motive for ODI.

Originality/value
These results seem to emerge from the policy changes that were undertaken during the sample period. Consistent with subgroup tests, this study finds that the main purposes of China’s ODI in the top 100 countries are natural resource explorations and production line replacements.
Cortisol synergizing with endoplasmic reticulum stress induces regulatory T‐cell dysfunction
Authors: Luo Jiangping , Zhou Caijie , Wang Shiqi , Tao Shuang , Liao Yun , Shi Zhaohui , Tang Zhiyuan , Wu Yongjin , Liu Yu , Yang Pingchang 
Published: July 2023

AbstractThe dysfunction of regulatory T cell (Treg) is associated with the pathogenesis of many immune diseases. The regiments used to re‐establish Treg's function are currently unsatisfactory and need to be improved. The purpose of this study is to elucidate the synergistic effects of cortisol and endoplasmic reticulum (ER) stress on impairing regulatory T cell functions. In this study, blood samples were collected from patients with food allergy (FA). Immune cells were purified from blood specimens by flow cytometry. A mouse model of FA was established with ovalbumin as a specific antigen. We observed that serum cortisol levels of FA patients were negatively correlated with peripheral Treg counts. Overwhelmed ER stress status was detected in Tregs of FA patients. The antigen‐specific immune response induced ER stress in Tregs, which was exacerbated by concurrent cortisol exposure. ER stress mediated the effects of cortisol on impairing the immune suppressive ability of Tregs. The expression of Rnf20 was observed in Tregs upon exposure to cortisol. Rnf20 reduced the expression of Foxp3 and transforming growth factor (TGF)‐β in Tregs. Rnf20 inhibition re‐established the immunosuppressive functions of Tregs obtained in patients with FA. The experimental FA in mice was attenuated by inhibition of Rnf20 in Tregs. In summary, specific immune response in synergy with cortisol to induce the expression of Rnf20 in Tregs. Rnf20 reduces the levels of Foxp3 and TGF‐β to impair the immune suppressive function. Inhibition of Rnf20 can restore the immune suppressive ability of Tregs obtained from FA patients.
Climatic adaptation explains responses to Pleistocene oscillations and diversification in European vipers
Authors: Lucchini Nahla , Kaliontzopoulou Antigoni , Lourdais Olivier , Martínez‐Freiría Fernando 
Published: July 2023

AbstractAimAllopatric speciation is the primary mode of diversification in the Mediterranean Basin. However, the contribution of climatic adaptation during this process is contradictory. In this work, we investigate the eco‐evolutionary processes that drove diversification in this region, using European vipers as a case study. We describe the climatic requirements of different lineages to compare their responses to the Pleistocene climatic oscillations and tackle the evolutionary mechanisms underlying their diversification.LocationEurasia and North Africa.TaxonEuropean vipers (genus Vipera).MethodsWe used ecological niche modelling (ENM) to identify the climatic requirements of 24 Vipera lineages and infer past range dynamics associated with their diversification during the Pleistocene. To test whether climatic niches varied across lineages, we calculated the phylogenetic signal of different climatic variables and examined the relationship with phylogenetic relatedness. To investigate climatic niche evolution and test for phylogenetic niche conservatism (PNC), we quantified pairwise niche overlap in sister phylogenetic units under a 3D hypervolume approach.ResultsENM identified temperature annual range, precipitation of wettest month and precipitation of driest quarter as the most important climatic variables related to the distribution of most lineages, validating Pelias clade as cold‐adapted, and Vipera 1 and Vipera 2 as warm‐adapted clades. Projections to past conditions varied among clades, with Pelias and Vipera 1 having more similar responses, while Vipera 2 exhibited greater variability. We found significant phylogenetic signal in one temperature‐related and two humidity‐related climatic variables and detected high complexity in ecological niche evolution across the phylogeny, both rejecting the hypothesis of PNC.Main ConclusionsClimatic adaptation played a significant role in driving diversification among European vipers. Cold‐adapted and warm‐adapted lineages presented similar climatic requirements and remarkable responses to Pleistocene stages, resulting in an intricate pattern of niche divergence along the phylogeny that favours local adaptation rather than PNC.
The regulation of chromatin configuration at AGAMOUS locus by LFR‐SYD‐containing complex is critical for reproductive organ development in Arabidopsis
Authors: Lin Xiaowei , Yuan Tingting , Guo Hong , Guo Yi , Yamaguchi Nobutoshi , Wang Shuge , Zhang Dongxia , Qi Dongmei , Li Jiayu , Chen Qiang , Liu Xinye , Zhao Long , Xiao Jun , Wagner Doris , Cui Sujuan , Zhao Hongtao 
Published: July 2023

SUMMARYSwitch defective/sucrose non‐fermentable (SWI/SNF) chromatin remodeling complexes are evolutionarily conserved, multi‐subunit machinery that play vital roles in the regulation of gene expression by controlling nucleosome positioning and occupancy. However, little is known about the subunit composition of SPLAYED (SYD)‐containing SWI/SNF complexes in plants. Here, we show that the Arabidopsis thaliana Leaf and Flower Related (LFR) is a subunit of SYD‐containing SWI/SNF complexes. LFR interacts directly with multiple SWI/SNF subunits, including the catalytic ATPase subunit SYD, in vitro and in vivo. Phenotypic analyses of lfr‐2 mutant flowers revealed that LFR is important for proper filament and pistil development, resembling the function of SYD. Transcriptome profiling revealed that LFR and SYD shared a subset of co‐regulated genes. We further demonstrate that the LFR and SYD interdependently activate the transcription of AGAMOUS (AG), a C‐class floral organ identity gene, by regulating the occupation of nucleosome, chromatin loop, histone modification, and Pol II enrichment on the AG locus. Furthermore, the chromosome conformation capture (3C) assay revealed that the gene loop at AG locus is negatively correlated with the AG expression level, and LFR‐SYD was functional to demolish the AG chromatin loop to promote its transcription. Collectively, these results provide insight into the molecular mechanism of the Arabidopsis SYD‐SWI/SNF complex in the control of higher chromatin conformation of the floral identity gene essential to plant reproductive organ development.
Systematic literature review informing the 2022 update of the EULAR recommendations for the management of ANCA-associated vasculitis (AAV): part 1—treatment of granulomatosis with polyangiitis and microscopic polyangiitis
Authors: Schirmer Jan Henrik , Sanchez-Alamo Beatriz , Hellmich Bernhard , Jayne David , Monti Sara , Luqmani Raashid Ahmed , Tomasson Gunnar 
Published: July 2023

ObjectiveTo summarise and update evidence to inform the 2022 update of the EULAR recommendations for the management of antineutrophil cytoplasm antibody-associated vasculitis (AAV).MethodsA systematic literature review (SLR) was performed to identify current evidence regarding treatment of AAV. PubMed, EMBASE and the Cochrane library were searched from 1 February 2015 to 25 February 2022. The evidence presented here is focused on the treatment of granulomatosis with polyangiitis and microscopic polyangiitis.Results3517 articles were screened and 175 assessed by full-text review. Ninety articles were included in the final evidence synthesis. Cyclophosphamide and rituximab (RTX) show similar efficacy for remission induction (level of evidence (LoE) 1a) but RTX is more effective in relapsing disease (LoE 1b). Glucocorticoid (GC) protocols with faster tapering result in similar remission rates but lower rates of serious infections (LoE 1b). Avacopan can be used to rapidly taper and replace GC (LoE 1b). Data on plasma exchange are inconsistent depending on the analysed trial populations but meta-analyses based on randomised controlled trials demonstrate a reduction of the risk of end-stage kidney disease at 1 year but not during long-term follow-up (LoE 1a). Use of RTX for maintenance of remission is associated with lower relapse rates compared with azathioprine (AZA, LoE 1b). Prolonged maintenance treatment results in lower relapse rates for both, AZA (LoE 1b) and RTX (LoE 1b).ConclusionThis SLR provides current evidence to inform the 2022 update of the EULAR recommendations for the management of AAV.
Genomic analysis of the MLST population structure and antimicrobial resistance genes associated with Salmonella enterica in Mexico
Authors: Gómez-Baltazar Adrián , Godínez-Oviedo Angélica , Vázquez-Marrufo Gerardo , Vázquez-Garcidueñas Ma. Soledad , Hernández-Iturriaga Montserrat 
Published: July 2023

Salmonella enterica is one of the most commonly reported foodborne pathogens by public health agencies worldwide. In this study, the multilocus sequence typing (MLST) population structure and frequency of antimicrobial resistance (AMR) genes were evaluated in S. enterica strains from Mexico ( n = 2561). The most common sources of isolation were food (44.28%), environment (27.41%), animal-related (24.83%), and human (3.48%). The most prevalent serovars were Newport (8.51%), Oranienburg (7.03%), Anatum (5.78%), Typhimurium (5.12%), and Infantis (4.57%). As determined by the 7-gene MLST scheme, the most frequent sequence types were ST23, ST64, and ST32. The core genome MLST scheme identified 132 HC2000 and 195 HC900 hierarchical clusters, with the HC2000_2 cluster being the most prevalent in Mexico ( n = 256). A total of 78 different AMR genes belonging to 13 antimicrobial classes were detected in 638 genomic assemblies of S. enterica. The most frequent class was aminoglycosides (31.76%), followed by tetracyclines (12.53%) and sulfonamides (11.91%). These results can help public health agencies in Mexico prioritize their efforts and resources to increase the genomic sequencing of circulating Salmonella strains. Additionally, they provide valuable information for local and global public health efforts to reduce the impact of foodborne diseases and AMR.