bluuebunny/crossref_metadata_2025_split huggingface dataset:
Andrological aspects of prolactin secretion disorders
Authors: Tyuzikov I. A. , Grekov E. A. , Smirnov A. V. 
Published: September 2023

Since the discovery of prolactin, scientific and practical interest in it has been focused exclusively from the standpoint of female endocrinology and reproductology. At the same time, the physiology and pathophysiology of prolactin in men, due to the historically established interpretation of the functions of this hormone only as an endocrine regulator of the female reproductive system, have remained insufficiently studied for a long time. However, in recent decades, convincing scientific evidence has begun to accumulate that prolactin is just as important for men as for women. It has been shown that in both sexes prolactin not only exhibits important classical (reproductive) effects, but has a wide range of non-productive physiological functions in many organs and cells. In particular, to date, not only reproductive, but various hormonal-metabolic, psychosomatic, immune-inflammatory, sexual disorders caused by disorders of prolactin secretion (hypo- and hyperprolactinemia) have been described.The review article, based on the available modern literature, examines the general issues of endocrinology and physiology of prolactin in men, as well as the main andrological manifestations of disorders of its secretion by male reproduction, male sexual function and prostate gland.
Can evaluation of seminal plasma and serum anti-Müllerian hormone be useful in the diagnosis of male infertility? (Literature review)
Authors: Ryzhkov A. I. , Sokolova S. Yu. , Shormanov I. S. 
Published: September 2023

Background. Anti-Müllerian hormone (AMH) is secreted in men by Sertoli cells and plays an important role in the development of the male reproductive organs. High expression of AMH during embryonic development contributes to the regression of the Müllerian (paramesonephric) ducts; in the absence of AMH, the Müllerian ducts develop into the female internal genital organs. In adulthood, the clinical value of measuring AMH in serum and seminal plasma remains controversial. It is assumed that AMH, as a marker of the functional state of Sertoli cells, can be useful in the diagnosis of male infertility.Aim. To determine the clinical value of measuring serum and seminal plasma AMH levels in the diagnosis of male infertility by examining the current evidence base in the world literature.Materials and methods. A search was made for publications devoted to the study of the role of AMH in the diagnosis of male infertility in the international database PubMed, in the scientific electronic library eLIBRARY.RU and in the Google Scholar search engine. There were no restrictions regarding the status and period of publication.Results and conclusion. The results of the analysis indicate the absence of a significant relationship between the parameters of the ejaculate and the serum concentration of AMH, which does not allow using this indicator to assess male fertility. Serum AMH is of no value in the differential diagnosis of obstructive and non-obstructive azoospermia, the prediction of assisted reproductive technologies outcomes, and the prediction of testicular biopsy outcomes in the general non-obstructive azoospermia patient population. It is likely that serum AMH may be useful in predicting testicular biopsy results in patients with Klinefelter’s syndrome and idiopathic non-obstructive azoospermia.The clinical application of measuring the level of AMH in seminal plasma is limited by the high variability of this indicator, probably due to the dependence on the volume of the ejaculate and exposure to semen proteolytic enzymes. This indicator may be useful for the differential diagnosis of obstructive and non-obstructive azoospermia. In obstructive azoospermia, AMH is not detected in seminal plasma, but undetectable AMH concentrations can also be observed in patients with non-obstructive azoospermia, which reduces the differential value of this indicator. A promising direction is the use of AMH concentration in seminal plasma to predict the recovery of sperm motility after cryopreservation.
Surgical correction of vestibulo-vaginal frictional dislocation of urethra in postcoital cystitis
Authors: Komyakov B. K. , Shevnin M. V. , Tarasov V. A. , Nazarov T. Kh. , Shpilenya E. S. , Rychkov I. V. 
Published: September 2023

Aim. To improve the results of surgical treatment of patients with recurrent postcoital cystitis.Material and methods. From 2005 to 2023, extravaginal transposition of the urethra according to the method developed by us (patent No. RU2408296C1 from 10.01.2011) and its modification (patent No. RU2686948C1 from 18.06.2018) was performed in 502 women aged from 18 to 61 years (average age 29.6 ± 7.2 year) at the Urology Department of the I.I. Mechnikov Northern State Medical University. The main part of patients was operated at the Center of Urology of the City Multidisciplinary Hospital No. 2 (St. Petersburg).Results. Out of 502 women we operated on, 370 (73.7 %) were examined in the distant postoperative period. A satisfactory result was observed in 338 (91.4 %) of them. The operation proved to be ineffective in 32 (8.6 %) women. Repeated transposition of the urethra was performed in 17 patients (3.4 %).Сonclusion. The indication for extravaginal urethral transposition is the association of sexual intercourse with episodes of cystitis exacerbations. The high efficacy of this operation for the prevention and treatment of postcoital cystitis is achieved through the correct selection of women as well as compliance with all technical features of the proposed surgical intervention.
Renal hemodynamics in patients with resistant hypertension and type 2 diabetes mellitus
Authors: Manukyan M. A. , Falkovskaya A. Yu. , Zyubanova I. V. , Solonskaya E. I. , Lichikaki V. A. , Ryabova T. R. , Vtorushina A. A. , Khunkhinova S. A. , Skomkina I. A. , Yevtukh A. A. , Gusakova A. M. , Mordovin V. F. 
Published: September 2023

Aim To study renal hemodynamics in patients with resistant arterial hypertension (RAH) in combination with type 2 diabetes mellitus (DM2) and to identify factors involved in the increase in intrarenal vascular resistance.Material and methods This study included 59 patients (25 men) with RAH in combination with DM2. Mean age of patients was 60.3±7.9 years; 24-h blood pressure (24-BP) (systolic, diastolic, SBP/DBP) was 158.0±16.3 / 82.5±12.7 mm Hg during the treatment with 4.3 [4.0;5.0] antihypertensive drugs; glycated hemoglobin (HbA1c) was 7.5±1.5 %; estimated glomerular filtration rate (eGFR) was 73.1±21.8 ml/min / 1.73 m2 (CKD-EPI equation). Measurement of office BP, 24-h BP monitoring, renal artery (RA) Doppler, routine lab tests including determination of GFR (CKD-EPI), 24-h urine albumin excretion, and ELISA measurement of blood lipocalin-2, cystatin C, high-sensitive C-reactive protein (hsCRP), and asymmetric dimethylarginine (ADMA) were performed for all patients.Results Incidence of increased RA resistive index (RI) was 39% despite the high rate of vasodilator treatment (93% for renin-angiotensin-aldosterone system inhibitors, 78% for calcium antagonists). According to a correlation and regression analysis, RA RI values were correlated with the kidney function (r=-0.46, p<0.001 for eGFR, r=0.56; p=0.006 for lipocalin-2), age (r=0.54, p<0.001), increases in concentrations of hsCRP (r=0.35, p<0.001) and ADMA (r=0.39, p=0.028), the increase in vascular stiffness (r=0.59, p<0.001 for pulse BP (PBP) as well as DM2 duration, and HbA1c (r=0.33, p<0.001 for both). The independent association of RA RI with the age, PBP, and duration of DM2 was confirmed by the results of multivariate regression analysis. According to the ROC analysis, the threshold level of RA RI corresponding to a decrease in GFR <60 ml / min / 1.73 m2 was ≥0.693 conv. units.Conclusion In more than one third of patients with RAH in combination with DM2, increased renal vascular resistance was documented, which was closely associated with impaired kidney function, age, DM2 duration and severity, and markers of low-grade inflammation, endothelial dysfunction, and vascular stiffness. The value of RA RI ≥0.693 conv. units was a threshold for the development of chronic kidney disease (CKD).
On the methodological approach to the development of federal state educational standards of higher education of the fourth generation in terms of universal competencies
Authors: Мартынов В.Г. , Душин А.В. , Иванова А.Д. 
Published: September 2023

Рассматривается проблема неудовлетворительного состояния действующих образовательных стандартов в части универсальных компетенций. Показано, что практико-ориентированный компетентностный подход привел к снижению уровня социально-гуманитарной подготовки в вузах, фактическому отказу от научной методологии, формирования научного мировоззрения и общероссийской гражданской идентичности обучающихся. Выражается мнение, что использование soft skills в качестве универсальных компетенций не в полной мере соответствует задачам современного высшего образования. Предложен методологический подход к определению наименований и структуры универсальных компетенций, их формулировок и результатов обучения для образовательных стандартов четвертого поколения, основанный на формах общественного сознания.
The problem of the unsatisfactory state of the current educational standards in terms of universal competencies is considered. It is shown that the practice-oriented competence-based approach has led to a decrease in the level of social and humanitarian training in universities, the actual rejection of scientifi c methodology, the formation of a scientifi c worldview and the all-Russian civic identity of students. The opinion is expressed that the use of soft skills as universal competencies does not fully correspond to the tasks of modern higher education. A methodological approach is proposed to determine the names and structure of universal competencies, their formulations and learning outcomes for the fourth generation educational standards, based on the forms of social consciousness.
The concept and composition of word-combination readiness as an aspect of the formation of communicative competence of cadets in teaching a foreign language
Authors: Крылова О.В. 
Published: September 2023

Определяются понятия «словосочетание» и «словосочетательная готовность» с позиций ряда гуманитарных наук, включая фреймологию и искусственный интеллект. Представлена типология фреймов (фраз, коллокаций) применительно к курсам иностранного (английского) языка для инженерных профилей. Доказывается важность использования многокомпонентных единиц для моделирования речи. Описан процесс формирования фразовой готовности, даны теоретические и практические рекомендации по организации обучения иностранному языку с целью совершенствования коммуникативной компетенции. Показаны перспективы запуска многокомпонентного категориально-комбинаторного мультимедийного словарного приложения.
The concepts of “phrase” and “collocation readiness” are defi ned from the standpoint of a number of humanities, including frameology and artifi cial intelligence. A typology of frames (phrases, collocations) is presented in relation to foreign (English) language courses for engineering profi les. The importance of using multicomponent units for speech modeling is proved. The process of formation of phrasal readiness is described, theoretical and practical recommendations are given on the organization of teaching a foreign language in order to improve communicative competence. The prospects for launching a multicomponent categorical-combinatorial multimedia dictionary application are shown.
Tables and diagrams as a teaching tool for additional professional education programs
Authors: Дьяченко Н.В. , Масалева М.В. 
Published: September 2023

Рассматривается использование в образовательном процессе таблиц и схем как инструментов наглядного представления учебных материалов по программам дополнительного профессионального образования. Представлен генезис проблемы их применения, начиная с древности. Обоснована ее актуальность в условиях современности. Выделяются особенности реализации программ дополнительного образования, ряд проблем, решение которых возможно благодаря использованию таблиц и схем в процессе обучения. Подробно рассмотрены положительные и отрицательные стороны, условия эффективного использования таблиц и схем. Представлены результаты проведенного исследования.
The use of tables and diagrams in the educational process as tools for visual presentation of educational materials on programs of additional professional education is considered. The genesis of the problem of their application, starting from antiquity, is presented. Its relevance in modern conditions is substantiated. The features of the implementation of additional education programs, a number of problems, the solution of which is possible due to the use of tables and diagrams in the learning process, are highlighted. The positive and negative sides, the conditions for the eff ective use of tables and diagrams are considered in detail. The results of the conducted research are presented.
THE CORRELATION OF THE NOTIONS “ISKUSSTVO” AND “KRA SOTA” / “ART” AND “BEAUTY”
Authors: Банькова Н.В. 
Published: September 2023

Выявляется соотношение объемов значений понятий «искусство» и «красота» / “art” и “beauty”. Предпринята комплексная попытка рассмотреть вышеупомянутые понятия. Впервые сопоставлены результаты их этимологического анализа, проведен анализ их значений; на основе изучения лексикографических источников и контекстного исследования обнаружены совпадающие значения. Проведенный анализ выявил значительное расхождение в количестве созначений русского слова «искусство» (пять созначений) и английского аналога “art” (шестнадцать созначений) и незначительное различие (шесть созначений) слова «красота» и слова “beauty” (семь созначений).
The article aimed to reveal the volume of the notions “iskusstvo” and “krasota” / “art” and “beauty” in the Russian and the English languages. Th e scientifi c novelty is that a complex approach to the study of the above-mentioned notions allowed to compare the results of etymological analysis of these lexemes, analyse their meanings. On the basis of the study of dictionaries and contexts there were revealed coinciding meanings. Th e comparative analysis of the words “iskusstvo” and “krasota” / “art” and “beauty” revealed the diff erence between the meanings’ volume. Th e study demonstrated that the volume of the notion «iskusstvo» (5 meanings) / “art” (16 meanings) doesn’t coincide with the volume of the notion “krasota” (6 meanings) / “beauty” (7 meanings).
TEMPORAL CHARA CTERISTICS OF “AGGRESSION”, “LACK OF SPIRITUAL VALUES” AS RUSSIAN CULTURE REPRESENTATIVES’ ANTI-VALUES
Authors: Ильина В.А. , Ракушина Е.А. 
Published: September 2023

Рассматривается темпоральная характеристика антиценностей «агрессия» и «бездуховность» с опорой на темпоральные шкалы, используемые в качестве инструмента анализа содержания антиценностей в языковом сознании носителей русской культуры. Материалом исследования являются две базовые антиценности, данные психосемантического эксперимента. Шкалирование применяется в качестве метода исследования. Сопоставительный анализ темпоральных характеристик двух антиценностей – «агрессия» и «бездуховность» – позволяет выявить зоны совпадения и зоны расхождения в области их характеристик. В зону совпадения входит признак «долговременность», а в зону расхождения – такие признаки, как непрерывность («бездуховность»), сиюминутность («агрессия»), кратковременность («агрессия»).
The article considers the temporal characteristics of the anti-values aggression and lack of spiritual values based on temporal scales used as a tool for analyzing the content of anti-values in the linguistic consciousness of Russian culture representatives. Two basic anti-values and the data of a psychosemantic experiment became the research material of the study. Scaling is used as a research method. Based on the results of the comparative analysis of the temporal characteristics of two anti-values aggression and lack of spiritual values, the authors identify the areas of coincidence and areas of divergence of their characteristic features. Th e zone of coincidence includes such sign as long-term, and the zone of discrepancy includes signs as continuous (lack of spiritual values), spontaneous (aggression), short-term (aggression).
THE PHENOMENON OF «HAPPINESS» AND ITS LINGUO - CULTUROLOGICAL REPRESENTATION IN RUSSIAN AND CHINESE IDIOMS
Authors: Цзя М. 
Published: September 2023

Определяются образная и ценностная составляющие концепта «счастье» в русской и китайской лингвокультуре. Понятие концепта раскрывается с позиции отображения в нем связи языка, мышления и культуры. Анализируются способы вербализации концепта «счастье» в идиоматических единицах русского и китайского языков, актуализируются его лингвокогнитивные и прагматические характеристики, внутренняя структура. В результате проведенного исследования выяснено, что эти два языка следуют фактически одному и тому же метонимическому принципу, говоря о счастье и описывая преимущественно физиологические эффекты эмоций, возникающие в результате переживания состояния счастья.
The article focuses on the defi nition of the fi gurative and value component of the concept of «happiness» in Russian and Chinese linguistic culture. Th e notion of the concept is revealed from the position of displaying in it the connection of language, thinking and culture. Th e article analyzes the ways of verbalizing the concept of «happiness» in the idiomatic units of the Russian and Chinese languages, updates its linguo-cognitive and pragmatic characteristics and internal structure. As a result of the study, it has been found that these two languages follow the same metonymic principle when speaking about happiness, describing mainly the physiological eff ects of emotions arising from experiencing a state of happiness.
«STUDENT – TEACHER» INTERNET COMMUNICATION: FROM TRA DITIONAL FORMULAS OF POLITENESS TO A NEW NETWORK ETIQUETTE
Authors: Попова О.А. , Соболева О.В. 
Published: September 2023

Рассматривается вопрос реализации принципов и норм сетевого этикета на современном этапе интернет-коммуникации, а также важности их соблюдения при взаимодействии студента и преподавателя. Формулируются основные принципы и правила сетевого этикета, способствующие успешной коммуникации и уберегающие от коммуникативных неудач. Выделяются и анализируются наиболее частотные отклонения от норм сетевого этикета в переписке «студент – преподаватель». Обозначаются основные тенденции, свойственные современному сетевому взаимодействию. В результате доказывается, что в настоящее время происходит формирование нового молодежного (студенческого) сетикета, для которого характерны прагматичность, ориентация на оперативность передачи информации и широкое использование визуальных средств, однако отказ от традиционных правил и принципов сетевого этикета может стать причиной коммуникативных неудач.
The article addresses the question of how the principles and norms of network etiquett e (netiquett e) are implemented at the present stage of Internet communication and how important it is to follow them in student-teacher interactions. Th e basic principles and rules of netiquett e that contribute to successful communication and protect from communication failures are formulated. Th e most frequent deviations from the norms of netiquett e in the correspondence “student – teacher” are identifi ed and analyzed. Th e main trends characteristic of modern network interaction are outlined. As a result, it is proved that a new youth (student) netiquett e is currently being formed, which is characterized by pragmatism, focus on the promptness of information transmission and the widespread use of visual means, but the rejection of traditional rules and principles of netiquett e can cause communication failures.
On the Stability of a Cournot Dynamic Game Under the Influence of Information
Authors: Sarafopoulos G , Papadopoulos K 
Published: September 2023

In this paper we study the impact of information on the stability of a dynamic Cournot – type duopoly game. We suppose that one player searches for information about his rival before he makes his decision. We study how the amount of information acquired by player, influences the stability of Nash equilibrium. The game is modeled with a system of two difference equations. Existence and stability of equilibrium of this system are studied. We show numerically that the model gives chaotic and unpredictable trajectories as a consequence of change in the information parameter, but in our case there are also stable trajectories for each value of the information parameter. To provide some numerical evidence for the chaotic behavior of the system we present various numerical results including bifurcation diagrams, strange attractors, Lyapunov numbers and sensitive dependence on initial conditions.

Keywords: Cournot dynamic game, Nash equilibrium, Stability, Chaos.
Human Capital Capabilities for Sustainable Competitive Advantage in Tourism Industry
Authors: Črnjar K 
Published: September 2023

The aim of this article is to discuss the main Travel and Tourism competitiveness indicators which take into consideration human capital capabilities as a key factor when determining competitiveness. Human capital competitiveness in the tourism industry will be analyzed based on the internationally accepted methodology Travel and Tourism Competitiveness Index (TTCI). Analysis will focus on the globally most competitive countries in tourism and on countries in the Southern European region. The research shows that even though human capital is not always emphasized when competiveness evaluation is carried out in the tourism industry, human capital capabilities are a key factor taken into account in the competitiveness assessment data. In many countries the competitiveness of human capital in tourism is lower than desired, providing opportunities for additional investment in competitiveness through education and more-efficient labor market practices. Research methods used in the study include the systematic and logical analysis of scientific literature and synthesis.

Keywords: human capital, labor market, travel & tourism competitiveness, tourism industry
The Effective Personnel Selection Via Multi-criteria Decision-making Method Analytic Hierarchy Process (AHP): A Web-based Application
Authors: Özbek D , Yaralioğlu K , Karagöz E 
Published: September 2023

Decision-making is a process that people encounter in their daily or business lives. The process aims at reaching a conclusion depending on the aims of the people. Multiple factors affect the process of decision-making depending on the characteristics of these factors. These factors that affect the process of decision-making complicate encountered problems, and in this stage as a solution, multi-criteria decision-making methods are preferred to use by the decision-makers. Decision-making methods are categorized according to specific goals served to give the best results to decisionmakers. Certainly, the most important goal for organizations is to ensure that the right person works in the right job in line with his/her goals. The problems that are encountered by human resources managers is decision-making problems. A small mistake made by human resource department during the personnel selection can cause negative consequences in short or long term for companies. In this study, a web-based application was developed in order to solve the personnel-selection problems of human resources management. A model that is based on multi-criteria selection has been developed to ensure the elimination of candidates through the program based on solution algorithm of Analytic Hierarchy Process (AHP), which is one of the most widely used decision-making methods designed as a web-based application so far.

Keywords: multi-criteria decision-making, analytic hierarchy process, human resources management, personnel selection, web-based application