bluuebunny/crossref_metadata_2025_split huggingface dataset:
Inanspruchnahme einer Spezialsprechstunde für psychisch
kranke Eltern
Authors: Brandl Eva Janina , Reiche Susanne , Hullmeine Lisa , Mick Inge , Hadzibegovic Jasmina , Zerbe Lena-Karoline , Bermpohl Felix , Schouler-Ocak Meryam 
Published: January 2023

Zusammenfassung
Hintergrund Eltern mit psychischen Erkrankungen haben in der Peripartalzeit
einen großen Unterstützungsbedarf. Bislang gibt es nur wenige
spezialisierte Angebote. In dieser Untersuchung wird eine Spezialsprechstunde
für psychisch kranke Eltern ausgewertet.
Methoden Es wurden demographische und krankheitsbezogene Daten der
Patient*innen der Elternsprechstunde in der Psychiatrischen
Universitätsklinik der Charité im St. Hedwig Krankenhaus
(N=279) aus dem Zeitraum 06/2017 bis 12/2021
ausgewertet.
Ergebnisse Die Sprechstunde wurde vor allem von Personen mit affektiven
Störungen, hohem Bildungsgrad und guter Therapieadhärenz in
Anspruch genommen. Personen mit Migrationshintergrund erhielten seltener eine
ambulante Psychotherapie.
Diskussion Die Daten zeigen eine hohe Inanspruchnahme des ambulanten
Angebots, jedoch eher durch eine Population mit höherem
sozioökonomischem Status. Aufgrund der klinischen Relevanz wäre
ein Ausbau von Angeboten für Eltern wünschenswert.
Synthesis of the CDF Ring System of Hexacyclinic Acid
Authors: Prunet Joëlle , Audic Alexandre 
Published: January 2023

AbstractDiverse approaches to prepare the nine-membered ring precursor of the DEF fragment of hexacyclinic acid are described, culminating in the synthesis of the CDF ring system of this natural product. The key steps are a Michael addition/elimination sequence and an original intramolecular Tsuji–Trost reaction of an enol with an allylic alcohol.
Uterine Scar Evaluation during the Postpartum: Pleading for Extradecidual Suturing during Cesarean Section
Authors: Kesrouani Assaad K. , Abdelkhalek Yara , Abdallah Wael , Chaccour Christian , Hatoum Inaam , Richa Freda 
Published: January 2023

Objective Our objective is to evaluate ultrasound differences in uterine scar between techniques using extramucosal suturing and full thickness suturing of the uterine incision.
Study Design A retrospective observational study included cases of primary cesarean section. At 6-week postpartum, we evaluated by endovaginal ultrasound two elements in the sagittal view: the thickness of the uterine scar and the surface of defect (niche). Hysterotomy sites closed using a running full-thickness technique including the uterine mucosa (group 1) were compared to hysterotomies operated by the same surgeon but with extramucosal suturing (group 2). The operator switched from the running suture technique to extramucosal in 2013.
Results The study included 241 patients (115 cases in group 1 that were compared to 126 cases in group 2). There were no significant differences in age or body mass index between the two groups. Cesarean scar and niche were detectable in the entire studied population. There was a significant difference in both uterine scar thickness (5.8 vs. 6.2 mm, p = 0.02) and the presence and size of the niche (49 vs. 40 mm2, p = 0.001) in transvaginal ultrasound performed at 6-week postpartum.
Conclusion Extramucosal suturing of the uterine scar seems to be associated with a better outcome on the postpartum ultrasound evaluation.
Key Points
Indian Perspective of Burnout Among Plastic Surgeons
Authors: Karanjkar Ankur , Panse Nikhil , Panse Smita , Sahasrabudhe Parag 
Published: January 2023

Abstract
Introduction Over the last decade, the term “Burnout” has become familiar term in all walks of life, particularly medicine. Emotional exhaustion, depersonalization, and a low sense of personal accomplishment make up the triad. At least a third of plastic surgeons are having burnout according to the western literature. Data on burnout in Indian plastic surgeons is lacking. We have made an attempt to analyze the incidence and factors responsible for burnout among plastic surgeons in India.
Materials and Methods An online survey was conducted in India to assess burnout among plastic surgeons from June to November 2019. Consent, demographic information, stress-related factors, the abbreviated Maslach Burnout Inventory (aMBI), and Satisfaction with Medicine were all included section wise in the survey. Both used scales were validated. Data were gathered using Google forms, then uploaded to an Excel file and analyzed. A multivariable and univariable analysis of factors associated with burnout was carried out.
Results Twenty-two percent of 330 plastic surgeons who responded were assessed to have moderate to high emotional exhaustion, 5% had moderate to high depersonalization, and 3% had low personal accomplishment. The overall burnout rate was 8.2%. Seventy-three percent of plastic surgeons enjoyed a good to very good quality of life. Great over-volume of work, mid-career practicing plastic surgeons and professional satisfaction with work were found to have a significant association with burnout on multivariate analysis.
Conclusions Plastic surgeons in India suffer an overall burnout rate of 8.2% with a multifactorial etiology. This occupational hazard is preventable and reversible. Plastic surgeons need to be vigilant about this and seek help whenever required.
External Validation of Three Burn-Specific Mortality Prediction Models in Adult Burn Patients at a Tertiary Care Hospital in India
Authors: Sharma Sneha , Tandon Raman 
Published: January 2023

Abstract
Background Several burn-specific mortality prediction models have been formulated and validated in the developed countries. There is a dearth of studies validating these models in the Indian population. Our objective was to validate three such models in the Indian burn patients.
Methods A prospective observational study was performed after ethical clearance on consecutive eligible consenting burn patients. Patient demographics, vitals, and results of hematological workup were collected. Using these. the Abbreviated Burn Severity Index (ABSI), the revised Baux score (rBaux), and the Fatality by Longevity, APACHE II score, Measured extent of burn, and Sex score (FLAMES) were calculated. The discriminative ability of the ABSI, rBaux, and the FLAMES was tested using the receiver operating characteristic (ROC) curve at 30 days and the area under the ROC curve (AUROC) compared. A p-value ≤ 0.05 was considered significant. Probability of death was calculated using these models. Hosmer–Lemeshow goodness of fit test was run.
Results The ABSI (AUROC 0.7497, 95% CI 0.67796–0.82141), rBaux (AUROC 0.7456, 95% CI 0.67059–0.82068) and FLAMES (AUROC 0.7119, 95% CI 0.63209–0.79172), had fair discriminative ability. The Hosmer–Lemeshow test reported that ABSI and rBaux were a good fit for the Indian population, while FLAMES was not a good fit.
Conclusion The ABSI and rBaux had a fair discriminative ability and were a good fit for the adult patients with 30 to 60% thermal and scald burn patients. FLAMES despite having fair discriminative ability was not a good fit for the study population.
Comparative Evaluation of the Increase in Enamel Hardness Post-External Bleaching after Using Casein Phosphopeptide Amorphous Calcium Phosphate Fluoride (CPP-ACPF) and 5% Sodium Fluoride (NaF) Remineralizing Agents
Authors: Irmaleny Irmaleny , Hidayat Opik Taofik , Yolanda Yolanda , Tobing Elisabeth Lumban 
Published: January 2023

Abstract
Objective The purpose of this study was to analyze the increase in enamel hardness post-external bleaching after remineralized with casein phosphopeptide amorphous calcium phosphate fluoride (CPP-ACPF) and 5% sodium fluoride (NaF) and the difference in increased enamel hardness between CPP-ACPF and NaF materials.
Materials and Methods The study was true experimental in vitro using 30 samples of mandibular premolars. All samples were bleached using 40% hydrogen peroxide. The samples were divided into three groups of 10 samples each; group I as a control without application of remineralization material, group II was given an application of CPP-ACPF (GC Tooth Mousse Plus: GC Europe, Lot #201130B), and group III was given an application of 5% NaF (Clinpro White Varnish: 3M ESPE, Lot #NA62322) Then the entire samples were stored in artificial saliva. The hardness of the samples was measured using a Vickers hardness tester before bleaching, after bleaching, and after remineralization for 7, 14, and 21 days.
Statistical Analysis Analysis of the data used was an analysis of variance test to assess differences in the increase in enamel hardness between groups and paired t-tests and to determine differences in enamel hardness in each group.
Results This study showed that there was an increase in the enamel hardness after bleaching which was remineralized with CPP-ACPF and 5% NaF. There was a difference in the increased enamel hardness between teeth remineralized with CPP-ACPF and 5% NaF. The enamel hardness of CPP-ACPF was higher compared with 5% NaF after remineralization of 7, 14, and 21 days.
Conclusion There was an increase in the enamel hardness after external bleaching that was remineralized with CPP-ACPF and 5% sodium fluoride (NaF). There was a difference in the increased enamel hardness between teeth remineralized with CPP-ACPF and 5% sodium fluoride (NaF). CPP-ACPF showed a higher enamel hardness value than 5% NaF.
Occupational and Functional Outcomes following Patellofemoral Arthroplasty in U.S. Military Servicemembers
Authors: Fisher Tuesday F. , Rider Danielle E. , Waterman Brian R. , Belmont Philip J. 
Published: January 2023

AbstractThe functional outcomes in patients undergoing patellofemoral arthroplasty (PFA) with high occupational demands have not been fully examined. This study assessed return to work and conversion to TKA rates following PFA in a young, military cohort. Patient demographics, pain scores, and surgical information were retrospectively collected for all active-duty military members who underwent PFA over a 4-year period. The data were then analyzed to calculate return to work, conversion to TKA, and perioperative complications rates. A total of 48 servicemembers with 60 total PFAs (36 unilateral, 12 bilateral) were included, with a mean follow up of 2.2 years. At the final follow-up, 83% of servicemembers returned to military service or completed their service obligation after PFA. Conversion to TKA occurred in three (6.2%) patients at an average of 2.4 years after PFA, resulting in a PFA annual revision rate of 2.3%. The mean numeric rating scale for pain improved from 4.9 ± 2.6 at baseline to 2.5 ± 2.0 postoperatively (p < 0.001). Servicemembers with at least one prior ipsilateral knee procedure had a significantly decreased odds ratio (OR) for both occupational outcome failure (OR, 0.03; 95% confidence interval [CI], 0–0.29) and overall failure (OR, 0.13; 95% CI, 0.02–0.78). At an average of 2 years following PFA, 83% of military members returned to duty, with a low rate of revision to TKA. Prior ipsilateral knee procedure decreased the probability of medical separation.
Level of Evidence IV
Heterotopic Digital Replantation in Mutilating Hand Injuries: An Algorithmic Approach Based on 53 Cases and Literature Review
Authors: Chang Tommy Nai-Jen , Hsu Chung-Chen , Dafydd Hywel , Sachanandani Neil S. , Chen Lisa Wen-Yu , Chen Yi-Chieh , Lin Yu-Te , Lin Chih-Hung , Lin Cheng-Hung 
Published: January 2023

Abstract
Background Reconstruction of the mutilated hand is one of the most difficult challenges for hand microsurgeons. When multiple digits are amputated, orthotopic digital replantation of the available remnants may not adequately restore the hand function. In such cases, heterotopic digital replantation may provide a more functional reconstruction.
Methods Between 1997 and 2018, 53 patients with mutilating hand injuries were treated with heterotopic digital replantation at our institution. A retrospective chart review was conducted to determine the details of the injury, indications for heterotopic digital replantation, and functional outcomes.
Results In total, 173 digits were amputated from 53 patients (one patient suffered from bilateral hand injuries, so totally 54 hands). Sixty-eight digits underwent heterotopic digital replantation, 30 digits had orthotopic digital replantation, and 75 stumps were terminalized. The survival rate of digits treated by heterotopic digital replantation and orthotopic digital replantation was 83.8% (57/68) and 86.7% (26/30), respectively (p = 1). Tripod grip was achieved in 83.3% (45/54) of patients following replantation and optional secondary reconstructive surgeries.
Conclusion Heterotopic digital replantation is a practical and reliable method for achieving optimal hand function following mutilating hand injuries. The basic principles are to restore a functional thumb in the first instance, followed by at least two adjacent fingers against which the thumb can oppose. This method is particularly indicated when orthotopic digital replantation of the available amputated parts would yield a suboptimal result.
Trends in Indian Ocean marine fisheries since 1950: synthesis of reconstructed catch and effort data
Authors: Zeller D. , Ansell M. , Andreoli V. , Heidrich K. 
Published: January 2023

Context Contrary to other ocean basins, Indian Ocean catches have increased consistently since 1950, although reported data are known to be incomplete. Fish is a crucial food source in the Indian Ocean; however, ineffective management often empowers over-exploitation. Aims We synthesised and reviewed Indian Ocean reconstructed catch and effort data by fishing sector and fishing country at the ocean-basin scale. Methods We aggregated reported and reconstructed unreported catch and effort data for the Indian Ocean and derived catch-per-unit-effort (CPUE) time-series by sector. Key results Indian Ocean rim country catches dominated in the Indian Ocean. Small-scale catches in the Indian Ocean have grown continuously by over 300% from 1.9 × 106 tonnes (Mg) year−1 in 1950 to 6.5 × 106 tonnes year−1 by 2018. By contrast, total industrial catches from the Indian Ocean have reached a plateau at ~8.5 × 106 tonnes year−1 since the late 1990s, after having steadily risen from very low levels in the early 1960s. Unreported catches declined from 45 to 25% of total catches. Total fishing effort, driven by the industrial sector, has increased 30-fold since 1950 from 0.4 × 109 to 11 × 109 kW-days by 2010, whereas CPUE has declined 78%, with steeper declines in the small-scale (>80% since 1950) than in the industrial sector (65% from its 1981 peak). Conclusions The different sectoral patterns in the Indian Ocean compared with other ocean basins are likely to be due to the region’s high dependence on small-scale fisheries and the later onset but swift growth of industrial fishing. The declining CPUE suggests strong decreases in stock biomass caused by strongly increasing fishing effort, especially in the industrial sector. Implications Indian Ocean countries should prioritise lower-impact well-managed domestic small-scale fisheries to maximise long-term, sustainable nutrient supply for local livelihoods.
Generation and analysis of context-specific genome-scale metabolic models derived from single-cell RNA-Seq data
Authors: Gustafsson Johan , Anton Mihail , Roshanzamir Fariba , Jörnsten Rebecka , Kerkhoven Eduard J. , Robinson Jonathan L. , Nielsen Jens 
Published: January 2023

Single-cell RNA sequencing combined with genome-scale metabolic models (GEMs) has the potential to unravel the differences in metabolism across both cell types and cell states but requires new computational methods. Here, we present a method for generating cell-type-specific genome-scale models from clusters of single-cell RNA-Seq profiles. Specifically, we developed a method to estimate the minimum number of cells required to pool to obtain stable models, a bootstrapping strategy for estimating statistical inference, and a faster version of the task-driven integrative network inference for tissues algorithm for generating context-specific GEMs. In addition, we evaluated the effect of different RNA-Seq normalization methods on model topology and differences in models generated from single-cell and bulk RNA-Seq data. We applied our methods on data from mouse cortex neurons and cells from the tumor microenvironment of lung cancer and in both cases found that almost every cell subtype had a unique metabolic profile. In addition, our approach was able to detect cancer-associated metabolic differences between cancer cells and healthy cells, showcasing its utility. We also contextualized models from 202 single-cell clusters across 19 human organs using data from Human Protein Atlas and made these available in the web portal Metabolic Atlas, thereby providing a valuable resource to the scientific community. With the ever-increasing availability of single-cell RNA-Seq datasets and continuously improved GEMs, their combination holds promise to become an important approach in the study of human metabolism.
Coherence in translation
Authors: Sanders José , Evers-Vermeul Jacqueline 
Published: January 2023

AbstractWhen comparing old and new Bible translations, differences are striking at all discourse levels. This paper concentrates on variations in the representation of subjective cognition and reasoning of subjects in the discourse. A corpus-based analysis was conducted that compared the domains of use of causal fragments in Dutch Bible translations that were either old, contemporary and loyal, or “easy”. In a close comparison of Bible translations, differences between domains of use are analysed in more detail. In old translations, the character’s subjective reasoning is clearly separated from the narrator’s utterances. By contrast, in modern translations, causal reasoning is more intertwined between character and narrator, resulting in shared reasoning.
Evolution is an arc along a timeline
Authors: Andorno Cecilia 
Published: January 2023

AbstractGrowing evidence shows the role of teachers gestures not only in L2 learning (Stam & Tellier, 2021) but also in supporting learning in the L1 classroom (Alibali et al., 2014;Crowder, 1996;Wilson et al., 2014). The current study aims at contributing to this last perspective. Based on data from a 3rd grade plurilingual classroom in an Italian school, it observes the ‘catchments’ (McNeill, 2000) in teacher’s gesticulation during a cycle of lessons on “The origin of life”. The analysis identifies conceptual components based on thetime is spacemetaphor associated with gestures, and observes their alignment with lexical items – either technical or common words (evolution, ages, ancestors, archaic;change, back, old) – in speech. The gesture-word association supports both the conceptualization of the notions and the acquisition of the related lexicon: gestures connect recurring concepts to their different verbalisations, ensuring a conceptually coherent representation over the lesson; they establish synonimic relations between technical and common words; and they can also work as memory triggers towards and between concepts and lexical units.
Bodily engagement in the learning and teaching of grammar
Authors: Suñer Ferran , Roche Jörg , Van Vossel Liesbeth 
Published: January 2023

Abstract
Cognitive Linguistics claims that language is not purely abstract and arbitrary, but meaningful and grounded in
concepts arising from our embodied experiences (Oakley, 2007). The potential of using
imagery and bodily representations to explain the conceptual motivation of grammar has been widely recognized in the context of
language acquisition and teaching. This study investigates whether an increase of learners’ bodily engagement through the
performance of bodily movements and locomotion produces even greater learning outcomes. To this end, we refer to Talmy’s (2000) Force Dynamic System to conduct a pretest-posttest interventional study
with two groups of learners dealing with the German modal verb system. Whereas the first group watched multimedia animations (low
bodily engagement), the second group was asked to perform bodily movements in line with the force-dynamic notions underlying the
different modal verbs (high bodily engagement). The results show that both groups produced similar learning gains and that an
increased bodily engagement could not be associated directly with a significantly better performance.
Road surface and inventory extraction from mobile LiDAR point cloud using iterative piecewise linear model
Authors: Zeybek Mustafa , Biçici Serkan 
Published: January 2023

Abstract
Roads are one of the main characteristics of cities, and their data should be updated periodically. In this study, a new automatic method is proposed for extracting road surface information and road inventory from a Mobile LiDAR System-based point cloud. The proposed method consists of four steps. First, a three-dimensional point cloud is acquired using the mobile LiDAR scanning raw data. To improve the extraction accuracy, irrelevant points are removed from the point cloud. Piecewise linear models are used in the third step to classify the road surface. Road geometric characteristics such as centerline, profile, cross-section, and cross slope are extracted in the final step. The manually obtained road boundary is compared with the extracted road boundary to assess the classification results. Completeness, correctness, quality, and accuracy measures are range from

97
%

to

99
%

. When comparing these measures with previous studies, the proposed method produces one of the highest ones.
Cardio-respiratory interactions in response to lower-body negative pressure
Authors: Fadil Rabie , Verma Ajay Kumar , Sadeghian Farshid , Blaber Andrew Philip , Tavakolian Kouhyar 
Published: January 2023

Abstract
Objective: The goal of this study is to investigate the potential of the physiological interaction between heart rate and blood pressure, and cardiorespiratory coupling to track the progression of simulated hemorrhage, as well as differentiate individuals with low tolerance (LT) from the ones with high tolerance (HT) to hypovolemia. Approach: Wavelet transform coherence and convergent cross-mapping techniques were employed to study the physiological interdependence and the causal relationship between heart rate, blood pressure, and respiration in nineteen subjects who underwent a progressive lower body negative pressure (LBNP) protocol. Main results: The interaction between blood pressure and heart rate to maintain homeostasis was higher in the LT group during baseline, and LBNP simulated mild, moderate, and severe hemorrhage. The significant time of interaction between blood pressure, and respiration, and the causal effect of blood pressure on respiration were higher in the HT group during baseline compared to the LT group. HT participants also had a higher causal effect of respiration on blood pressure compared to LT. The calculated metrics to distinguish LT from HT subjects achieved a sensitivity of 58–83%, accuracy of 63-84%, and an area under the ROC curve of 74–86%, while the overlap of LT individual responses with HT was 0-33%. Significance: The outcomes of this study indicate the potential of cardiorespiratory coupling, and heart rate and blood pressure interaction toward tracking the progression of hemorrhage and distinguishing individuals with low tolerance to hypovolemia from those with high tolerance. Measurements of such interactions could improve clinical outcomes for patients with low tolerance to hypovolemia and therefore reduce morbidity and mortality through early implementation of life-saving interventions.