bluuebunny/crossref_metadata_2025_split huggingface dataset:
High-output heart failure following gunshot injury and traumatic arteriovenous fistula
Authors: Palić Benjamin , Mandić Ante , Prskalo Zrinko , Brizić Ivica 
Published: February 2023

Background Heart failure due to high cardiac output rarely occurs. Few cases of post-traumatic arteriovenous fistula (AVF) as a cause of high-output failure were reported in the literature. Methods Herein, we report a case of 33-year-old male who was admitted to our institution due to symptoms of heart failure. He reported a gunshot injury of the left thigh 4 months earlier, when he had been shortly hospitalized and discharged 4 days later. Since the gunshot injury he had exertional dyspnea and left leg edema, so the diagnostic procedures were performed. Results Clinical examination revealed distended neck veins, tachycardia, slightly palpable liver, left leg edema, and thrill over the left thigh. Due to high clinical suspicion, duplex ultrasonography of the left leg was performed that verified femoral AVF. Operative treatment of AVF was made with prompt resolution of symptoms. Conclusions This case wants to emphasize the importance of proper clinical examination, and duplex ultrasonography in all cases of penetrating injuries.
Over-accrual in Bayesian adaptive trials with continuous futility stopping
Authors: Barrado Leandro Garcia , Burzykowski Tomasz 
Published: February 2023

Background: We explore frequentist operating characteristics of a Bayesian adaptive design that allows continuous early stopping for futility. In particular, we focus on the power versus sample size relationship when more patients are accrued than originally planned. Methods: We consider the case of a phase II single-arm study and a Bayesian phase II outcome-adaptive randomization design. For the former, analytical calculations are possible; for the latter, simulations are conducted. Results: Results for both cases show a decrease in power with an increasing sample size. It appears that this effect is due to the increasing cumulative probability of incorrectly stopping for futility. Conclusion: The increase in cumulative probability of incorrectly stopping for futility is related to the continuous nature of the early stopping, which increases the number of interim analyses with accrual. The issue can be addressed by, for instance, delaying the start of testing for futility, reducing the number of futility tests to be performed or by setting stricter criteria for concluding futility.
Dual plate fixation of proximal humerus fractures: Retrospective review and surgical technique
Authors: Alqahtani Saad M , Aljamaan Yousef , Abusultan Ammar , Alzahrani Mohammad M 
Published: February 2023

Introduction Recent interest has been directed towards dual plate fixation for comminuted proximal humerus fractures, with an aim to improve construct stability and thus improve patient outcomes while decreasing the risk of fracture-associated complications. We present our experience with this technique in a case series of patients with proximal humerus fractures and describe our surgical technique. Methodology This was a single-center retrospective case series of patients presenting with an acute (<6 weeks) proximal humerus fracture who underwent ORIF with dual plating fixation. Patient, fracture, and surgical data were collected. All patient outcomes were evaluated using Constant–Murley shoulder score and Single Assessment Numeric Evaluation. Results Our series included nine patients with a mean age of 46.2 years (range: 27–70 years old). All fractures healed within 4 months and no complications were encountered. At 1 year follow-up, the mean SANE score was 69.4% and the mean Constant Murley shoulder score was 78.9 (range: 70–96). Conclusion Our current series shows that applying the dual plating technique in severely comminuted proximal humerus fractures provides adequate fixation and thus good patient outcomes. Further research is required before this technique can be strongly recommended for management of these complex fractures. Level of Evidence Level 5.
The quality of informational social support in online health communities: A content analysis of cancer-related discussions
Authors: Petrič Gregor , Cugmas Marjan , Petrič Rok , Atanasova Sara 
Published: February 2023

Objective Informational social support is one of the main reasons for patients to visit online health communities (OHCs). Calls have been made to investigate the objective quality of such support in the light of a worrying number of inaccurate online health-related information. The main aim of this study is to conceptualize the Quality of Informational Social Support (QISS) and develop and test a measure of QISS for content analysis. A further aim is to investigate the level of QISS in cancer-related messages in the largest OHC in Slovenia and examine the differences among various types of discussion forums, namely, online consultation forums, online support group forums, and socializing forums. Methods A multidimensional measurement instrument was developed, which included 20 items in a coding scheme for a content analysis of cancer-related messages. On a set of almost three million posts published between 2015 and 2019, a machine-learning algorithm was used to detect cancer-related discussions in the OHC. We then identified the messages providing informational social support, and through quantitative content analysis, three experts coded a random sample of 403 cancer-related messages for the QISS. Results The results demonstrate a good level of interrater reliability and agreement for a QISS scale with six dimensions, each demonstrating good internal consistency. The results reveal large differences among the social support, socializing, and consultation forums, with the latter recording significantly higher quality in terms of accuracy (M = 4.48, P < .001), trustworthiness (M = 4.65, P < .001), relevance (M = 3.59, P < .001), and justification (M = 3.81, P = .05) in messages providing informational social support regarding cancer-related issues. Conclusions This study provides the research field with a valid tool to further investigate the factors and consequences of varying quality of information exchanged in supportive communication. From a practical perspective, OHCs should dedicate more resources and develop mechanisms for the professional moderation of health-related topics in socializing forums and thereby suppress the publication and dissemination of low-quality information among OHC users and visitors.
Anti-vaccination attitude trends during the COVID-19 pandemic: A machine learning-based analysis of tweets
Authors: To Quyen G , To Kien G , Huynh Van-Anh N , Nguyen Nhung TQ , Ngo Diep TN , Alley Stephanie , Tran Anh NQ , Tran Anh NP , Pham Ngan TT , Bui Thanh X , Vandelanotte Corneel 
Published: February 2023

Objective Vaccine hesitancy has been ranked by the World Health Organization among the top 10 threats to global health. With a surge in misinformation and conspiracy theories against vaccination observed during the COVID-19 pandemic, attitudes toward vaccination may be worsening. This study investigates trends in anti-vaccination attitudes during the COVID-19 pandemic and within the United States, Canada, the United Kingdom, and Australia. Methods Vaccine-related English tweets published between 1 January 2020 and 27 June 2021 were used. A deep learning model using a dynamic word embedding method, Bidirectional Encoder Representations from Transformers (BERTs), was developed to identify anti-vaccination tweets. The classifier achieved a micro F1 score of 0.92. Time series plots and country maps were used to examine vaccination attitudes globally and within countries. Results Among 9,352,509 tweets, 232,975 (2.49%) were identified as anti-vaccination tweets. The overall number of vaccine-related tweets increased sharply after the implementation of the first vaccination round since November 2020 (daily average of 6967 before vs. 31,757 tweets after 9/11/2020). The number of anti-vaccination tweets increased after conspiracy theories spread on social media. Percentages of anti-vaccination tweets were 3.45%, 2.74%, 2.46%, and 1.86% for the United States, the United Kingdom, Australia, and Canada, respectively. Conclusions Strategies and information campaigns targeting vaccination misinformation may need to be specifically designed for regions with the highest anti-vaccination Twitter activity and when new vaccination campaigns are initiated.
Polyurethane Scaffold vs Fascia Lata Autograft for Hip Labral Reconstruction: Comparison of Femoroacetabular Biomechanics
Authors: Capurro Bruno , Tey-Pons Marc , Carrera Anna , Marqués-López Fernando , Marín-Peña Oliver , Torres-Eguía Raúl , Monllau Joan Carles , Reina Francisco 
Published: February 2023

Background: The integrity of the acetabular labrum is critical in providing normal function and minimizing hip degeneration and is considered key for success in today’s hip preservation algorithm. Many advances have been made in labral repair and reconstruction to restore the suction seal. Purpose/Hypothesis: To compare the biomechanical effects of segmental labral reconstruction between the synthetic polyurethane scaffold (PS) and fascia lata autograft (FLA). Our hypothesis was that reconstruction with a macroporous polyurethane implant and autograft reconstruction of fascia lata would normalize hip joint kinetics and restore the suction seal. Study Design: Controlled laboratory study. Methods: Ten cadaveric hips from 5 fresh-frozen pelvises underwent biomechanical testing with a dynamic intra-articular pressure measurement system under 3 conditions: (1) intact labrum, (2) reconstruction with PS after a 3-cm segmental labrectomy, then (3) reconstruction with FLA. Contact area, contact pressure, and peak force were evaluated in 4 positions: 90º of flexion in neutral, 90º of flexion plus internal rotation, 90º of flexion plus external rotation, and 20º of extension. A labral seal test was performed for both reconstruction techniques. The relative change from the intact condition (value = 1) was determined for all conditions and positions. Results: PS restored contact area to at least 96% of intact (≥0.96; range, 0.96-0.98) in all 4 positions, and FLA restored contact area to at least 97% (≥0.97; range, 0.97-1.19). Contact pressure was restored to ≥1.08 (range, 1.08-1.11) with the PS and ≥1.08 (range, 1.08-1.10) with the FLA technique. Peak force returned to ≥1.02 (range, 1.02-1.05) with PS and ≥1.02 (range, 1.02-1.07) with FLA. No significant differences were found between the reconstruction techniques in contact area in any position ( P > .06), with the exception that FLA presented greater contact area in flexion plus internal rotation as compared with PS ( P = .003). Suction seal was confirmed in 80% of PSs and 70% of FLAs ( P = .62). Conclusion: Segmental hip labral reconstruction using PS and FLA reapproximated femoroacetabular contact biomechanics close to the intact state. Clinical Relevance: These findings provide preclinical evidence supporting the use of a synthetic scaffold as an alternative to FLA and therefore avoiding donor site morbidity.
Reverse Shoulder Arthroplasty for Patients with Massive Rotator Cuff Tears or Cuff Tear Arthropathies at a Minimum Follow-up of 7 Years
Authors: De La Selle Hugues , Lascar Tristan , Clappaz Pascal , Decrette Edouard , van Rooij Floris , Saffarini Mo , Obert Laurent 
Published: February 2023

Purpose To evaluate indications and factors that influence long-term clinical outcomes and revision rates for reverse shoulder arthroplasty (RSA) in shoulders with irreparable massive rotator cuff tears (mRCTs) or cuff tear arthropathies (CTAs). Methods The authors retrospectively evaluated a consecutive series of shoulders with no fracture sequelae that underwent primary RSA between 2011 and 2013. Independent observers collected demographic data, surgical techniques, and implant types, as well as primary outcome measures such as American Shoulder and Elbow Society (ASES) score and Constant score (CS). Study design Case series, level IV. Results From the initial series of 123 patients that underwent RSA, 29 patients died (24%) for reasons unrelated to the shoulder arthroplasty, 11 were lost to follow-up (9%), and 4 required revision surgery (3%). The final cohort of 79 patients comprised 55 women (70%), and 24 men (30%), aged 72.7 ± 7.0. At a final follow-up of 8.9 ± 0.6 years (range: 7.4-10.3) the absolute CS was 59.0 ± 16.2, the age-/sex-adjusted CS was 76.6 ± 41.2, and ASES was 77.1 ± 20.3. Univariable analysis revealed no associations for absolute CS, but revealed that age-/sex-adjusted CS was significantly lower for patients with high blood pressure (β = −15.8, p = .025). Conclusions At a minimum follow-up of 7.4 years, the absolute CS was 59.0 ± 16.2, the age-/sex-adjusted CS was 87.4 ± 24.1 and ASES was 77.1 ± 20.3. When stratifying the outcomes of RSA by indication, there were no significant differences in patients with mRCTs versus CTA in terms of absolute CS, age-/sex-adjusted CS, and ASES. Univariable analysis revealed no association with absolute and age-/sex-adjusted CS for type of indication or surgical approach.
Influence of Cavitation on Unsteady Vortical Flows in a Side Channel Pump
Authors: Wang Yefang , Zhang Fan , Yuan Shouqi , Chen Ke , Hong Feng , Appiah Desmond 
Published: February 2023

AbstractPrevious investigation on side channel pump mainly concentrates on parameter optimization and internal unsteady vortical flows. However, cavitation is prone to occur in a side channel pump, which is a challenging issue in promoting performance. In the present study, the cavitating flow is investigated numerically by the turbulence model of SAS combined with the Zwart cavitation model. The vapors inside the side channel pump firstly occur in the impeller passage near the inlet and then spread gradually to the downstream passages with the decrease of NPSHa. Moreover, a strong adverse pressure gradient is presented at the end of the cavity closure region, which leads to cavity shedding from the wall. The small scaled vortices in each passage reduce significantly and gather into larger vortices due to the cavitation. Comparing the three terms of vorticity transport equation with the vapor volume fraction and vorticity distributions, it is found that the stretching term is dominant and responsible for the vorticity production and evolution in cavitating flows. In addition, the magnitudes of the stretching term decrease once the cavitation occurs, while the values of dilatation are high in the cavity region and increase with the decreasing NPSHa. Even though the magnitude of the baroclinic torque term is smaller than vortex stretching and dilatation terms, it is important for the vorticity production along the cavity surface and near the cavity closure region. The pressure fluctuations in the impeller and side channel tend to be stronger due to the cavitation. The primary frequency of monitor points in the impeller is 24.94 Hz and in the side channel is 598.05 Hz. They are quite corresponding to the shaft frequency of 25 Hz (fshaft = 1/n = 25 Hz) and the blade frequency of 600 Hz (fblade = Z/n =600 Hz) respectively. This study complements the investigation on cavitation in the side channel pump, which could provide the theoretical foundation for further optimization of performance.
Fatigue Life Prediction for SiC/Al Materials Based on Path Planning Algorithm Considering Residual Stress
Authors: Shang Wenqian , Liu Xintian , Wang Xu , Wang Xiaolan 
Published: February 2023

AbstractTo explore the influence of path deflection on crack propagation, a path planning algorithm is presented to calculate the crack growth length. The fatigue crack growth life of metal matrix composites (MMCs) is estimated based on an improved Paris formula. Considering the different expansion coefficient of different materials, the unequal shrinkage will lead to residual stress when the composite is molded and cooled. The crack growth model is improved by the modified stress ratio based on residual stress. The Dijkstra algorithm is introduced to avoid the cracks passing through the strengthening base and the characteristics of crack steps. This model can be extended to predict crack growth length for other similarly-structured composite materials. The shortest path of crack growth is simulated by using path planning algorithm, and the fatigue life of composites is calculated based on the shortest path and improved model. And the residual stress caused by temperature change is considered to improve the fatigue crack growth model in the material. The improved model can well predict the fatigue life curve of composites. By analyzing the fatigue life of composites, it is found that there is a certain regularity based on metal materials, and the new fatigue prediction model can also reflect this regularity.
Force Analysis of the Overconstrained Mechanisms Based on Equivalent Stiffness Considering Limb Axial Deformation
Authors: Guo Jinwei , Zhao Yongsheng , Chen Bo , Zhang Guoxing , Xu Yundou , Yao Jiantao 
Published: February 2023

AbstractOverconstrained mechanism has the advantages of large bearing capacity and high motion reliability, but its force analysis is complex and difficult because the mechanism system contains overconstraints. Considering the limb axial deformation, taking typical 2SS+P and 7-SS passive overconstrained mechanisms, 2SPS+P and 7-SPS active overconstrained mechanisms, and 2SPS+P and 7-SPS passive-input overconstrained mechanisms as examples, a new force analysis method based on the idea of equivalent stiffness is proposed. The equivalent stiffness matrix of passive overconstrained mechanism is derived by combining the force balance and deformation compatibility equations with consideration of axial elastic limb deformations. The relationship between the constraint wrench magnitudes and the external force, limb stiffness is established. The equivalent stiffness matrix of active overconstrained mechanism is derived by combining the force balance and displacement compatibility equations. Here, the relationship between the magnitudes of the actuated wrenches and the external force, limb stiffness is investigated. Combining with the equivalent stiffness of the passive overconstrained mechanism, an analytical relationship between the actuated forces of passive-input overconstrained mechanism and the output displacement, limb stiffness is explored. Finally, adaptability of the equivalent stiffness to overconstrained mechanisms is discussed, and the effect of the limb stiffness on overconstrained mechanisms force distribution is revealed. The research results provide a theoretical reference for the design, research and practical application of overconstrained mechanism.
Spatio-temporal dynamics of resting-state brain networks are associated with migraine disability
Authors: Zhou Yan , Gong Liusheng , Yang Yushu , Tan Linjie , Ruan Lili , Chen Xiu , Luo Hua , Ruan Jianghai 
Published: February 2023

Abstract
Objective
The changes in resting-state functional networks and their correlations with clinical traits remain to be clarified in migraine. Here we aim to investigate the brain spatio-temporal dynamics of resting-state networks and their possible correlations with the clinical traits in migraine.

Methods
Twenty Four migraine patients without aura and 26 healthy controls (HC) were enrolled. Each included subject underwent a resting-state EEG and echo planar imaging examination. The disability of migraine patients was evaluated by Migraine Disability Assessment (MIDAS). After data acquisition, EEG microstates (Ms) combining functional connectivity (FC) analysis based on Schafer 400-seven network atlas were performed. Then, the correlation between obtained parameters and clinical traits was investigated.

Results
Compared with HC group, the brain temporal dynamics depicted by microstates showed significantly increased activity in functional networks involving MsB and decreased activity in functional networks involving MsD; The spatial dynamics were featured by decreased intra-network FC within the executive control network( ECN) and inter-network FC between dorsal attention network (DAN) and ECN (P < 0.05); Moreover, correlation analysis showed that the MIDAS score was positively correlated with the coverage and duration of MsC, and negatively correlated with the occurrence of MsA; The FC within default mode network (DMN), and the inter-FC of ECN- visual network (VN), ECN- limbic network, VN-limbic network was negatively correlated with MIDAS. However, the FC of DMN-ECN was positively correlated with MIDAS; Furthermore, significant interactions between the temporal and spatial dynamics were also obtained.

Conclusions
Our study confirmed the notion that altered spatio-temporal dynamics exist in migraine patients during resting-state. And the temporal dynamics, the spatial changes and the clinical traits such as migraine disability interact with each other. The spatio-temporal dynamics obtained from EEG microstate and fMRI FC analyses may be potential biomarkers for migraine and with a huge potential to change future clinical practice in migraine.
Reduced knee laxity and failure rate following anterior cruciate ligament reconstruction compared with repair for acute tears: a meta-analysis
Authors: Migliorini Filippo , Vecchio Gianluca , Eschweiler Jörg , Schneider Sarah-Marie , Hildebrand Frank , Maffulli Nicola 
Published: February 2023

AbstractBackgroundFollowing anterior cruciate ligament (ACL) tears, both repair and reconstruction may be performed to restore joint biomechanics and proprioception. The present study compared joint laxity, patient-reported outcome measures (PROMs), and rate of failure following primary repair versus reconstruction for ACL ruptures.MethodsThis meta-analysis followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Pubmed, Google scholar, Embase, and Web of Science were accessed in September 2022. All the clinical investigations comparing repair versus reconstruction for primary ACL tears were accessed. Studies reporting data on multiple ligament injuries settings were not eligible.ResultsData from eight articles (708 procedures) were collected. The mean length of the follow-up was 67.3 ± 119.4 months. The mean age of the patients was 27.1 ± 5.7 years. Thirty-six percent (255 of 708 patients) were women. The mean body mass index (BMI) was 24.3 ± 1.1 kg/m2. The mean time span from injury to surgery was 36.2 ± 32.3 months. There was comparability at baseline with regards to instrumental laxity, Lachman test, International Knee Document Committee (IKDC), and Tegner Scale (P > 0.1). Similarity between ACL reconstruction and repair was found in IKDC (P = 0.2) and visual analog scale (VAS) satisfaction (P = 0.7). The repair group demonstrated greater mean laxity (P = 0.0005) and greater rate of failure (P = 0.004).ConclusionACL reconstruction may yield greater joint stability and lower rate of failure compared with surgical repair. Similarity was found in PROMs.Level of evidence:III