bluuebunny/crossref_metadata_2025_split huggingface dataset:
Das Gesetz zur Versorgung mit Cannabis zu medizinischen und medizinisch-wissenschaftlichen Zwecken (Medizinal- Cannabisgesetz – MedCanG)
Authors: Ratzel Rudolf 
Published: January 2025

Zusammenfassung
Von der breiten Öffentlichkeit weniger beachtet als die unter bestimmten Rahmenbedingungen begrenzte Freigabe von Cannabis durch das KCanG, hat der Gesetzgeber mit dem MedCanG einen im Vergleich zur vorherigen Rechtslage vereinfachten Zugang zu medizinischem Cannabis geschaffen. Wahrgenommene Verordnungspraxis und ein genauer Blick ins Gesetz werfen die Frage auf, ob der Gesetzgeber nicht etwas über das Ziel der medizinisch indizierten und ärztlich verantworteten Versorgung mit medizinischem Cannabis hinausschießt. und letztlich zum 1.4.2024 in Kraft getreten ist, ist das MedCanG3 quasi in seinem Windschatten weitgehend unbeachtet ebenfalls zum 1.4.2024 in Kraft getreten. Dies ist umso bemerkenswerter als es faktisch und in Teilen wohl auch rechtlich zu einer weitgehenden Freigabe der Verordnung und damit des Vertriebs von Cannabis zu medizinischen Zwecken jedenfalls dann führt, wenn die Verordnung außerhalb der GKV, also auf Privatrezept (auch als E-Rezept) erfolgt. Außer Nabilon fallen diese Cannabisprodukte nicht mehr unter das BtMG. Eine Genehmigungspflicht der Krankenkasse, wie sie § 31 Abs. 6 SGBV mit hohen Hürden vorschreibt, existiert außerhalb der GKV nicht.4 Ob die Verordnung indiziert ist, entscheidet alleine der die Verordnung ausstellende Arzt (§ 3 Abs. 1 MedCanG). Eine besondere Qualifikation benötigt der verordnende Arzt nicht. Er muss jedenfalls nach dem MedCanG keine Praxis betreiben oder in einer medizinischen Einrichtung tätig sein, weil unterstellt werden kann, dass ein Großteil dieser Verordnungen ohnehin nicht zur Erstattung eingereicht werden. Ob der Arzt aus berufsrechtlichen Gründen in eigener Niederlassung oder in einer medizinischen Einrichtung tätig sein muss, steht auf einem anderen Blatt.5 Über den Botendienst einer Apotheke oder eine Versandapotheke kann man sich „sein“ Cannabis bequem nach Hause schicken lassen.6 Die Hürden sind niedrig und einschlägige Vertriebswege werden im Netz aggressiv beworben.7 Die nachfolgenden Ausführungen verstehen sich als Ergänzung zu Jacoby, Die Abgabe von medizinischem Cannabis im System der gesetzlichen Krankenversicherung, GesR 2024, 681 ff.
Towards the cosymplectic topology
Authors: Tchuiaga Stéphane 
Published: July 2023

Abstract
In this article, the cosymplectic analogue of the symplectic flux homomorphism of a compact connected cosymplectic manifold

(

M
,
η
,
ω

)

\left(M,\eta ,\omega )

with

∂
M
=
∅

\partial M=\varnothing

is studied. This is a continuous map with respect to the

C

0

{C}^{0}

-metric, whose kernel is connected by smooth arcs and coincides with the subgroup of all weakly Hamiltonian diffeomorphisms. We discuss the cosymplectic analogue of the Weinstein’s chart, and derive that the group

G

η
,
ω

(

M

)

{G}_{\eta ,\omega }\left(M)

of all cosymplectic diffeomorphisms isotopic to the identity map is locally contractible. A study of an analogue of Polterovich’s regularization process for co-Hamiltonian isotopies follows. Finally, we study Moser’s stability theorems for locally conformal cosymplectic manifolds.
Vilnius Editions from the End of the 16th and the Beginning of the 17th Century in Bulgaria
Authors: Polimirova Mariya 
Published: July 2023

The aim of this paper is to present the publications of the printing houses in Vilnius from the end of the 16th and the 17th century which have been preserved in the larger Bulgarian libraries and in the archives in Sofia, Plovdiv, and Rila Monastery. These are some of the liturgical books published by Peter Mstislavets, the Mamonichi brothers, and the printing house of the Holy Spirit Monastery. We are offering systematic information with brief descriptions of the preserved copies. We are tracing the distribution of these printed books and the ways of their penetration into the Bulgarian lands in the 16th –17th century, as well as their usage in the following centuries.
Wie mächtig sind Archive?
Authors: Maurus Heinz , Rennert Martin , Kretzschmar Robert , Bacia Jürgen , Talkenberger Heike , Bergman Eleonora , Sielemann Jürgen , Buchholz Matthias 
Published: July 2023

Im Oktober 2011 war die Vertretung des Landes Schleswig-Holstein beim Bund Gastgeberin der Tagung „Macht und Ohnmacht der Archive“. Kultur- und Archivwissenschaftlerinnen und -wissenschaftler, Archivarinnen und Archivare debattierten über Auftrag und Nutzen, Verantwortung und Leistung der Archive in einer weithin digitalisierten Wissensgesellschaft.
Die Archivwissenschaft in Deutschland ist auf die Herausforderung, die durch das von Kulturwissenschaftlerinnen und -wissenschaftlern in der Atmosphäre der Postmoderne geformte Verständnis des Archivs entstanden ist, bislang nicht ausführlich eingegangen. Mit dem hier dokumentierten Symposium wird die überfällige Auseinandersetzung mit diesen Positionen nun begonnen. Die Diskussion wurde dabei betont praxisorientiert und pragmatisch geführt. Die Beiträge verbinden archivwissenschaftliche Überlegungen mit der Präsentation ausgewählter Einzelthemen aus archivarischer Praxis und Archivgeschichte.
Optimalisasi Fungsi Masjid Sebagai Sentra Pemberdayaan Ekonomi Umat
Authors: Afiat Fathur , Wediawati Besse , Enggrani Fitri Lucky 
Published: July 2023

Judul skripsi dalam penelitian ini adalah Optimalisasi Fungsi Masjid Sebagai Sentra Pemberdayaan Ekonomi Umat. Tujuan penelitian ini adalah Untuk mengidentifikasi kelebihan dan kelemahan internal serta peluang dan kendala eksternal masjid Jami Assalam. Kemudian merumuskan strategi bagi Masjid Jami Assalam dalam kegiatan pemberdayaan ekonomi umat melalui masjid kampus. penelitian ini mengunakan metode observasi langsung dan wawancara mendalam yang selanjutnya dianalisa untuk mengetahui faktor internal dan eksternalnya. Berikutnya faktor-faktor tersebut dianalisa dengan menggunakan analisis SWOT. Hasil penelitian yang digambarkan pada diagram matriks SWOT menunjukan strategi yang dapat digunakan masjid Jami Assalam dalam melakukan kegiatan pemberdayaan ekonomi umat melalui masjid. Dengan cara memanfaatkan kelebihan dalam hal sumber dana yang berkelanjutan dari infak jumat, serta didukung dengan peluang adanya visi misi Universitas Jambi Untuk menjadi World Class Entrepreneur University maka dengan ini, dapat menjalin kerjasama antara pihak kampus dan masjid Jami Assalam untuk membuat program pemberdayaan ekonomi umat melalui masjid.
Kata Kunci: Fungsi Masjid, Pemberdayaan Ekonomi Umat
The Effectiveness of Group Guidance With Role-Playing Techniques to Reduce the Negative Impact of Smartphones
Authors: Aisyah Matahari Citra Prabawani Nurul , Nurmala Meila Dwi , Wibowo Bangun Yoga 
Published: July 2023

A smartphone is a form of technological development that can now assist various processes in human life, such as communicating, shopping, obtaining information, and learning. Students who use smartphones excessively tend to show negative behavior, such as decreased focus and learning outcomes. This study aims to determine the effectiveness of group counseling with the role-playing technique to reduce the negative impact of smartphones on class IX students of junior high school. This research belongs to the type of experimental research, with a total sample of 66 students of class IX junior high school. Sampling in this study was carried out using a purposive sampling technique so that the final sample was obtained, eight students in the high category as the research sample. The data collection technique uses a questionnaire, an instrument for smartphones' negative impact. The data obtained in the study were then analyzed using analytical techniques using the Wilcoxon signed rank test. The results showed a decrease from 77% to 62%. Based on these results, group guidance with role-playing techniques effectively reduces the negative impact of students' smartphones.
Pengaruh empon-empon dan prebiotik terhadap pertumbuhan benur Udang Vaname (Litopenaeus vannamei) dalam mengontrol bakteri Vibrio (Vibrio sp.)
Authors: Sumardi Sumardi , Handayani Kusuma , Susanto G. Nugroho , Oktavia Nuri , Prihadi Eko 
Published: July 2023

Udang vaname (Litopenaeus vanamei) merupakan salah satu udang yang berasal dari Pantai Pasifik Timur dari Sanora (Meksiko Utara) hingga Amerika Tengah dan Selatan Tumbes Peru. Udang vaname mempunyai nilai ekonomi dan dapat dibudayakan di Indonesia. Udang tersebut mampu beradaptasi pada kisaran salinitas yang lebar dan dapat dibudidayakan dengan padat tebar yang tinggi, sehingga akibat dari padat tebar udang yang semakin tinggi dapat menyebabkan timbulnya penyakit oleh bakteri, salah satunya Vibrio sp. Tujuan penelitian ini adalah untuk mengetahui pengaruh pemberian empon-empon dan prebiotik terbaik terhadap larva udang vaname stadium pots larva 1-post larva 8, dalam mengontrol bakteri vibrio (Vibrio sp.) di hatchery. Metode yang digunakan melalui pengukuran parameter yang meliputi tingkat kelangsungan hidup pertumbuhan panjang harian, kualitas air dan perhitungan Vibrio sp. Hasil penelitian menunjukan bahwa tingkat kelangsungan terbaik terdapat pada perlakuan D (Prebiotik 2 ppm + jahe 0,5 ppm + kunyit putih 0,5 ppm + jinten hitam 0,5 ppm) sebesar (75 %) dan E (Jahe 0,5 ppm + kunyit putih 0,5 ppm + jinten hitam 0,5 ppm) sebesar (76 %), pertumbuhan panjang harian tertinggi pada perlakuan E (Jahe 0,5 ppm + kunyit putih 0,5 ppm + jinten hitam 0,5 ppm) sebesar (0,47mm/hari), total bakteri vibrio terbaik terdapat pada perlakuan E (Jahe 0,5 ppm + kunyit putih 0,5 ppm + jinten hitam 0,5 ppm)sebesa (0,39 log CFU/ml). Kualitas air dari ke lima perlakuan tersebut menunjukan masih dalam kondisi normal mengikuti Standar Nasional Indonesia SNI 8037.1: 2014.
Extracción de ficocianina para uso como colorante natural: optimización por metodología de superficie de respuesta
Authors: Ruiz-Hernández Y.A. , Garza-Valverde E. , Márquez-Reyes J.R , García-Gómez C. 
Published: July 2023

La aplicación de Spirulina maxima para la formulación de alimentos utilizándola como pigmento ha aumentado en los últimos años por sus propiedades y beneficios a la salud. Además, es de interés la utilización de la ficocianina por sus efectos antinflamatorios, antioxidantes y anticancerígenos, actuando directamente en la reducción del estrés oxidativo, la apoptosis y los procesos inflamatorios en modelos in vivo. Sin embargo, uno de los problemas del uso de la ficocianina en alimentos es optimizar la extracción a una máxima concentración y con una buena estabilidad. En este estudio se utilizó un método de extracción en buffer de fosfatos con agitación como objetivo la optimización de los parámetros del proceso tales como pH, cantidad de biomasa y concentración de buffer para maximizar la concentración de ficocianina extraída, pureza y obtención de polvos de interés comercial, utilizando un análisis de superficie de respuesta. El estudio mostró que un incremento de la cantidad de biomasa y baja concentración de buffer de extracción potencializaba la producción de ficocianina, estos resultados dirigen hacia el uso de colorantes naturales en la industria alimentaria.
Extracción de pectina a partir de bagazo de manzana y su análisis
Authors: Vázquez-Chávez L. , Zarazúa-Sánchez Z. 
Published: July 2023

La extracción de pectina a partir de bagazo de manzana fue estudiada. La influencia del pH temperatura y tiempo de extracción sobre las variables rendimiento, fuerza del gel y grado de esterificación fue determinada utilizando análisis de varianza a un nivel de significancia del 0.05%. Se encontró que el pH y la temperatura influyen significativamente en el rendimiento sin embargo se observó que la fuerza del gel disminuyo paralelamente con el aumento del rendimiento. Se determinó un intervalo óptimo para la extracción de pectina pH 2.2 y 2.6, temperatura 60-87°C y tiempo de proceso 60 y 90 min. Se determinó peso molecular mediante viscosidad intrínseca obteniendo valores de entre 30000-50000 g/mol se observó una correlación positiva entre peso molecular y fuerza del gel de la pectina obtenida.
Bio-inspired algorithm-based hyperparameter tuning for drug-target binding affinity prediction in healthcare
Authors: Sharma Moolchand , Deswal Suman 
Published: July 2023

The greatest challenge for healthcare in drug repositioning and discovery is identifying interactions between known drugs and targets. Experimental methods can reveal some drug-target interactions (DTI) but identifying all of them is an expensive and time-consuming endeavor. Machine learning-based algorithms currently cover the DTI prediction problem as a binary classification problem. However, the performance of the DTI prediction is negatively impacted by the lack of experimentally validated negative samples due to an imbalanced class distribution. Hence recasting the DTI prediction task as a regression problem may be one way to solve this problem. This paper proposes a novel convolutional neural network with an attention-based bidirectional long short-term memory (CNN-AttBiLSTM), a new deep-learning hybrid model for predicting drug-target binding affinities. Secondly, it can be arduous and time-intensive to tune the hyperparameters of a CNN-AttBiLSTM hybrid model to augment its performance. To tackle this issue, we suggested a Memetic Particle Swarm Optimization (MPSOA) algorithm, for ascertaining the best settings for the proposed model. According to experimental results, the suggested MPSOA-based CNN- Att-BiLSTM model outperforms baseline techniques with a 0.90 concordance index and 0.228 mean square error in DAVIS dataset, and 0.97 concordance index and 0.010 mean square error in the KIBA dataset.
Syzygy of Sexual Polarities: A Juginan Psychological Elucidation of Ode to Grecian Urn
Authors: Khan Imdad Ullah , Ali Akbar , Hakeem Memoona 
Published: July 2023

This study examines the psychological symbolism in Keatsian poetry using analytical psychology. John Keats ‘Ode on a Grecian Urn’ is steeped in psychological, symbolic, and analytical perspectives, which are essential components of Jungian psychology/archetypal analysis. The current study aims to scrutinize the psychological and symbolic perspectives of Keats’s poem to understand the depth of psychic integration and archetypes in the text. This study analyzes ‘Ode on a Grecian Urn’ by deploying Carl Jung’s concepts of syzygy or complementation of psychic energies of anima in the males and animus in the females. The term syzygy signifies a union of opposites like anima and animus and the conscious or collective unconscious. This process of complementation or complementary opposite of integration in the ode has symbolic interaction between the conscious male persona (animus) and the collective unconscious female persona (anima). Based on a close reading of the poem from a Jungian perspective, the current study provides a psychological understanding of poetic creation by underlying the conscious acts and thinking of the author as psychic interactions. This study aims to understand the symbolic representation of opposing psychic energies in Keatsian poetry. Moreover, the study analyzes the interpretation and the balance of male and female energies in Keats' poetry mean for the conscious and unconscious parts of the mind, and its effect on the poetic creativity and inner peace of the author. Thereby, the study elaborated that Keatsian poetry is a true depiction of Jungian psychology.
OER interoperability educational design: enabling research-informed improvement of public repositories
Authors: Romero-Ariza Marta , Abril Gallego Ana M. , Quesada Armenteros Antonio , Rodríguez Ortega Pilar Gema 
Published: July 2023

IntroductionAccording to UNESCO, open educational resources (OERs) could be tools for meeting Objective for Sustainable Development 4, as long as they have the appropriate characteristics and sufficient quality to promote citizen education.MethodsThis work presents a quality analysis of OERs in a public repository using mixed methods techniques and a participatory approach.Results &amp; DiscussionThough the quantitative results show high mean values in all the dimensions, the qualitative analysis provides a better understanding of how key stakeholders perceive particular aspects and how we can take a step forward to enhance usability and improve OER psychopedagogical and didactic design. The triangulation of information from different sources strengthens consistency and reliability and provides a richer perspective to inform future work.
Serum BDNF levels and state anxiety are associated with somatic symptoms in patients with panic disorder
Authors: Li Jiaxin , Li Ru , Li Dazhi , Zhang Jian , Luo Xingguang , Zhang Yong 
Published: July 2023

BackgroundWe aimed to explore the predictive role of serum BDNF and anxiety-related variables in changes in somatic symptoms post-escitalopram treatment in panic disorder (PD) patients.MethodsNinety PD patients and 99 healthy controls (HCs) were enrolled. PD patients received an 8-week escitalopram treatment. All patients were administered the Panic Disorder Severity Scale–Chinese Version (PDSS-CV) and State-Trait Anxiety Inventory (STAI) to assess panic and anxiety-related symptoms, respectively. Patient Health Questionnaire 15-item scale (PHQ-15) was performed to measure somatic symptoms, and the blood sample was collected to detect serum BDNF levels in all participants. We performed partial correlation analysis and multiple linear regression to explore correlates of PHQ-15 and predictors of PHQ-15 changes post-escitalopram treatment after controlling for age, gender, education levels (set as a dummy variable), the current duration, comorbid AP, and/or GAD.ResultsCompared to HCs, PD patients had lower serum BDNF levels and higher PHQ-15 scores that could be improved post-escitalopram treatment. Lower baseline STAI state (b = −0.07, p = 0.004), and PDSS-CV scores (b = −0.25, p = 0.007), but higher baseline serum BDNF levels (b = 0.35, p = 0.007) contributed to the prediction of PHQ-15 changes post-escitalopram treatment.ConclusionState anxiety, serum BDNF levels, and panic severity could predict changes in somatic symptoms post-escitalopram treatment, our results highlighted that serum BDNF could serve as a biological indicator for improving somatic symptoms in PD patients.
A Pragma-stylistic Study of Using the Present Tense in Narratives
Authors: العكيلي خالد 
Published: July 2023

It is normally known that '' literary language '' is different from '' ordinary language '' . That is , it is full of deviation , while, Prat,(1977:80) maintains that '' ordinary language '' is accompanied by ordinary rules , and outlines the work of Grice (1975 ) concerning the appropriate conditions that accepting a particular illocution-conditions which language users assume to be in effect. In this study , the present tense is not referred to as an indication to the moment of speaking or action . Rather , in narratives , it signals that this genre is '' unmediated '' . As such , the present tense is heavily used by writers , regardless of the time being , to signify that a text can be read at any time. Moreover, it can be noted , that the shift from the past to the simple present tense offers readers an opportunity to think seriously of what is being said . It, thus,invites thought and suspense . As far as the writer is concerned , it seems that the writer resorts to the simple present tense just to comment , highlight and criticize some incidents or events within the story.
Implementasi Forward Chaining untuk Mendiagnosis Kerusakan Motor Vespa Klasik pada Bengkel Skuter Ombur
Authors: Husain Husain , Herlinda Herlinda , Kasmawaru Kasmawaru , Nurdiansah Nurdiansah , Erna Erna , Putra Andi Hasriadi 
Published: July 2023

Vespa menjadi skuter legendaris yang tak lekang oleh waktu. Populasi Vespa dengan mesin 2 tak, alias Vespa lawas masih banyak berseliweran dan sangat mudah dijumpai. Banyak pengguna sepeda motor vespa klasik yang tak paham mengenai perbaikan kendaraan sehingga, butuh mekanik atau bengkel jika kendaraan mereka mengalami masalah ataupun kerusakan. Apabila kendaraan motor mereka mengalami kerusakan maka perlu dibawa ke bengkel untuk diperbaiki oleh ahlinya. Namun masih adanya kendala yang dialami mekanik yaitu harus mencari tahu apa permasalahannya, dikarenakan banyak mekanik atau teknisi baru yang belum paham tentang kerusakan-kerusakan motor vespa tersebut. Pada penelitian ini penulis membuat sistem pakar berbasis web untuk mendiagnosis kerusakan pada motor vespa klasik. Metode penelitian menggunakan forward chaining untuk mengukur suatu fakta berdasarkan gejala-gelaja kerusakan pada motor vespa klasik. Pada sistem ini diinput tujuh jenis kerusakan dan masing-masing kerusakan memiliki minimal empat gejala kerusakan sebagai basis pengetahuan ahli. Adapun proses analisis kerusakan digunakan metode forward chaining dan penentuan kerusakannya. Dengan adanya aplikasi sistem pakar ini, dapat memudahkan pemilik motor untuk mengetahui gejala kerusakan motornya, dan untuk montir atau mekanik pemula dapat memudahkan menganalisa/memperbaiki kerusakan motor vespa klasik. Vespa is a legendary scooter that is timeless. The population of Vespas with 2 stroke engines, aka old Vespas, is still a lot around and very easy to find. Many Users of classic Vespa motorbikes do not understand vehicle repair, so they need a mechanic/workshop if their vehicle is damaged. And if their motor vehicle is damaged, it needs to be taken to a garage to be repaired by an expert. However, there are still obstacles where mechanics have to find out what the problem is, because many new mechanics or technicians don't understand about the damage to the Vespa motorbike. In this study, the authors created a web-based expert system to diagnose damage to classic Vespa motors. The research method uses forward chaining to measure a fact based on the symptoms of damage to the classic Vespa motor. In this system, seven types of damage are input and each damage has at least four damage symptoms as an expert knowledge base. The damage analysis process uses the forward chaining method and determines the damage. With this expert system application, it can make it easier for motorbike owners to find out symptoms of motorbike damage, and for beginner mechanics or mechanics it can make it easier to analyze/repair damage to classic Vespa motorbikes.