bluuebunny/crossref_metadata_2025_split huggingface dataset:
Wet‐Etching‐Boosted Charge Storage in 1D Nitride‐Based Systems for Imitating Biological Synaptic Behaviors
Authors: Huang Chang‐Hsun , Wu Chia‐Yi , Lin Yen‐Fu , Chou Yi‐Chia , Lee Ko‐Tao 
Published: September 2023

AbstractNitride materials for memristors are benefited from their high response speed and high power density. The memristive effects on 1D nitride structures has not yet been elucidated. Hence, the activation of the memristive capability of nanowire (NW)‐based nitride memristors using an uncomplicated fabrication as single‐step anisotropic wet etching is proposed. Among nitrides, gallium nitride, a third‐generation semiconductor, exhibits properties potentially suitable for neuromorphic applications. The wet etchant considerably alters the chemisorbed molecules and dangling bonds associated with the surface states of the nanowires. A device based on such NWs which exhibits low power consumption with no required compliance current and forming voltage for operation is demonstrated. It can integrate all memristive capabilities, including multiple state switching, nonvolatile bipolar memory, and Ca2+ dynamics‐imitating synaptic actions. The examination of the memristive process also highlights the significance of altering surfaces in the devices, in addition to the shared principles that underlie biological and artificial synapses. The operating mode of the nitride‐nanowire devices can be controlled by controlling the formation/dissolution of the oxygen‐conductive path along the nanowires. Thus, the study realizes nanowire memristors based on a nitride material framework, that is promising for application in the 1D–1D system downsizing required for the bio‐inspired artificial synapse.
Hierarchically Porous Cellulose Membrane via Self‐Assembly Engineering for Ultra High‐Power Thermoelectrical Generation in Natural Convection
Authors: Sun Haodong , Tang Fengjie , Bi Yinghao , Sun Hao , Huang Liulian , Jiang Feng , Chen Lihui , Li Jianguo 
Published: September 2023

AbstractRenewable heat‐to‐power conversion based on thermoelectric strategy holds strong prospect toward clean electricity generation in low‐carbon society, in which its conversion performance is mainly decided by the temperature gradient. However, achieving a high temperature gradient spontaneously throughout the day in natural convection remains a significant challenge. Herein, cost‐effective, sustainable, and hierarchically porous cellulose membrane (HPCM) created through a simple self‐assembly engineering of cellulose molecules is proposed. Such HPCM boasts a unique structure of layered micro‐ and nanoscaled pores with ≈95% porosity, and correspondingly demonstrates >94% solar reflectance and >0.9 mid‐infrared emissivity. As a result, HPCM enables average temperature gradient of 14.5 °C and 76 mV output voltage of thermoelectric module during daytime natural convection, which are 17‐ and 30‐time higher than those of pristine device, respectively. Note that HPCM‐based thermoelectric module consistently generates an average output voltage of 44.2 mV all day. Such modules are seamlessly integrated into thermoelectric arrays to achieve high output voltage of ≈1.5 V and power density of ≈3 W m−2 over 90‐d period. The prepared HPCM marks a significant advancement in environmentally friendly, scalable, and viable thermoelectric conversion to power the low‐carbon society.
Sustained Release of Nitric Oxide‐Mediated Angiogenesis and Nerve Repair by Mussel‐Inspired Adaptable Microreservoirs for Brain Traumatic Injury Therapy
Authors: Liu Hsiu‐Ching , Huang Chu‐Han , Chiang Min‐Ren , Hsu Ru‐Siou , Chou Tsu‐Chin , Lu Tsai‐Te , Lee I‐Chi , Liao Lun‐De , Chiou Shih‐Hwa , Lin Zhong‐Hong , Hu Shang‐Hsiu 
Published: September 2023

AbstractTraumatic brain injury (TBI) triggers inflammatory response and glial scarring, thus substantially hindering brain tissue repair. This process is exacerbated by the accumulation of activated immunocytes at the injury site, which contributes to scar formation and impedes tissue repair. In this study, a mussel‐inspired nitric oxide‐release microreservoir (MINOR) that combines the features of reactive oxygen species (ROS) scavengers and sustained NO release to promote angiogenesis and neurogenesis is developed for TBI therapy. The injectable MINOR fabricated using a microfluidic device exhibits excellent monodispersity and gel‐like self‐healing properties, thus allowing the maintenance of its structural integrity and functionality upon injection. Furthermore, polydopamine in the MINOR enhances cell adhesion, significantly reduces ROS levels, and suppresses inflammation. Moreover, a nitric oxide (NO) donor embedded into the MINOR enables the sustained release of NO, thus facilitating angiogenesis and mitigating inflammatory responses. By harnessing these synergistic effects, the biocompatible MINOR demonstrates remarkable efficacy in enhancing recovery in mice. These findings benefit future therapeutic interventions for patients with TBI.
Liquid Metal‐Based Stable and Stretchable Zn‐Ion Battery for Electronic Textiles
Authors: Pu Jie , Cao Qinghe , Gao Yong , Wang Qiangzheng , Geng Zeyu , Cao Leiqing , Bu Fan , Yang Nute , Guan Cao 
Published: September 2023

AbstractElectronic textiles harmoniously interact with the human body and the surrounding environment, offering tremendous interest in smart wearable electronics. However, their wide application faces challenges due to the lack of stable and stretchable power electrodes/devices with multifunctional design. Herein, an intrinsically stretchable liquid metal‐based fibrous anode for a stable Zn‐ion battery (ZIB) is reported. Benefiting from the liquid feature and superior deformability of the liquid metal, optimized Zn ion concentration distribution and Zn (002) deposition behavior are observed, which result in dendrite‐free performance even under stretching. With a strain of 50%, the ZIB maintains a high capacity of 139.8 mAh cm−3 (corresponding to 83.0% of the initial value) after 300 cycles, outperforming bare Zn fiber‐based ZIB. The fibrous ZIB seamlessly integrates with the sensor, Joule heater, and wirelessly charging device, which provides a stable power supply for human signal monitoring and personal thermal management, holding promise for the application of wearable multifunctional electronic textiles.
Multicrystalline, Highly Oriented Thick‐Film Silicon from Reduction of Soda‐Lime Glass
Authors: Schall Ingrid , Ebbinghaus Stefan G. , Strelow Christian , Peiner Erwin 
Published: September 2023

AbstractThe study describes synthesis and characterization of > 10 µm thick multicrystalline (mc), highly oriented,p‐doped silicon layers by aluminothermic reduction of low‐cost soda‐lime glass. X‐ray diffraction shows a highly preferred (111)‐orientation and excellent crystallinity. Low compressive stress and very good crystallinity are confirmed by the peak position and width of the Raman LO‐phonon line, approaching the one of bulk single‐crystalline wafer material. Due to strong bonding to the glass substrate layer, spalling is not observed. A conductive aluminum‐rich oxide layer is formed underneath the silicon, serving as an electrical back‐contact for electronic devices. Using secondary ion mass spectrometry very low concentrations of 1014–1015 cm−3of impurities are found originating from the soda‐lime glass with an iron content below the detection limit. Furthermore, a plateau‐like, very homogenous Al concentration of ≈4 × 1018 cm−3over a thickness of ≈10 µm is found, which corresponds to the solubility of Al in Si at the process temperature. Complete electronic activation within the plateau region is confirmed by carrier concentration measurements using electrochemical capacitance–voltage profiling and Raman spectroscopy. Hole concentrations in the range of few 1018 cm−3are beneficial for thep‐type base material of full‐emitter cell mc‐silicon photovoltaic devices.
Resorbable Layered Double Hydroxides‐Based Composite Implants Synergistically Accelerates Critical‐Sized Defect Closure
Authors: Mohan Vimala Devi , V. K. Anupama Devi , Haridoss Pushkin Raj , Uthirappan Mani , Thada Raja Rajeshwari , Manikantan Syamala Kiran , Tiruchirapalli Sivagnanam Uma 
Published: September 2023

AbstractThe study focuses on the fabrication of a composite implant composed of MgAl layered double hydroxides (LDH), gelatin, and diosgenin and its regeneration potential in experimentally‐induced tibial defect in rabbits. The implant is fabricated by blending and lyophilization technique and eventually cross‐linked using glutaraldehyde. The implant is characterized by attenuated total reflectance (ATR) spectroscopy, scanning electron microscopy (SEM), atomic force microscopy (AFM), and compressive strength. A sustained release of diosgenin occurs over a period of 28 days. The osteogenic activity is analyzed by alkaline phosphatase activity and alizarin red S staining; that aid in determining the extent of biomineralization. The results also demonstrate that LGD100 implant stimulates the expression of genes associated with osteoblastic activities in MG‐63 cells, namely type I collagen, osteocalcin, and osteopontin. The bone regeneration capacity of diosgenin‐loaded gelatin‐based LDH implant is then tested by creating critical bone defects in the tibia of rabbits by using empty bone defects as controls. Periodic radiographs are taken which show promising results. Histological and immunohistochemical staining confirm that after treatment with LGD100, new bone is formed at the defect site. This study suggests that LGD100 implant aids in faster bone formation as it mimics the natural properties of bone.
Adipose‐Derived Mesenchymal Stem Cell‐Derived Exosomes Biopotentiated Extracellular Matrix Hydrogels Accelerate Diabetic Wound Healing and Skin Regeneration
Authors: Song Yanling , You Yuchan , Xu Xinyi , Lu Jingyi , Huang Xiajie , Zhang Jucong , Zhu Luwen , Hu Jiahao , Wu Xiaochuan , Xu Xiaoling , Tan Weiqiang , Du Yongzhong 
Published: September 2023

AbstractWound healing is an urgent clinical challenge, particularly in the case of chronic wounds. Traditional approaches to wound healing have limited therapeutic efficacy due to lengthy healing times, risk of immune rejection, and susceptibility to infection. Recently, adipose‐derived mesenchymal stem cell‐derived exosomes (ADSC‐exos) have emerged as a promising modality for tissue regeneration and wound repair. In this study, the development of a novel extracellular matrix hydrogel@exosomes (ECM@exo) is reported, which entails incorporation of ADSC‐exos into an extracellular matrix hydrogel (ECM hydrogel). This solution forms a hydrogel at physiological temperature (≈37 °C) upon local injection into the wound site. ECM@exo enables sustained release of ADSC‐exos from the ECM hydrogel, which maintains high local concentrations at the wound site. The ECM hydrogel displays good biocompatibility and biodegradability. The in vivo and in vitro results demonstrate that ECM@exo treatment effectively reduces inflammation and promotes angiogenesis, collagen deposition, cell proliferation, and migration, thereby accelerating the wound healing process. Overall, this innovative therapeutic approach offers a new avenue for wound healing via a biological hydrogel with controlled exosome release.
Deep Electronic State Regulation through Unidirectional Cascade Electron Transfer Induced by Dual Junction Boosting Electrocatalysis Performance
Authors: Zhang Wenlin , Shu Chonghong , Zhan Jiayu , Zhang Shenghu , Zhang Lu‐Hua , Yu Fengshou 
Published: September 2023

AbstractUnidirectional cascade electron transfer induced by multi‐junctions is essential for deep electronic state regulation of the catalytic active sites, while this advanced concept has rarely been investigated in the field of electrocatalysis. In the present work, a dual junction heterostructure (FePc/L‐R/CN) is designed by anchoring iron phthalocyanine (FePc)/MXene (L‐Ti3C2‐R, R═OH or F) heterojunction on g‐C3N4 nanosheet substrates for electrocatalysis. The unidirectional cascade electron transfer (g‐C3N4 → L‐Ti3C2‐R → FePc) induced by the dual junction of FePc/L‐Ti3C2‐R and L‐Ti3C2‐R/g‐C3N4 makes the Fe center electron‐rich and therefore facilitates the adsorption of O2 in the oxygen reduction reaction (ORR). Moreover, the electron transfer between FePc and MXene is facilitated by the axial Fe─O coordination interaction of Fe with the OH in alkalized MXene nanosheets (L‐Ti3C2‐OH). As a result, FePc/L‐OH/CN exhibits an impressive ORR activity with a half‐wave potential (E1/2) of 0.92 V, which is superior over the catalysts with a single junction and the state‐of‐the‐art Pt/C (E1/2 = 0.85 V). This work provides a broad idea for deep regulation of electronic state by the unidirectional cascade multi‐step charge transfer and can be extended to other proton‐coupled electron transfer processes.
An atypical Aymé‐Gripp phenotype detected by exome sequencing
Authors: Caiazza Martina , Budillon Alberto , Monda Emanuele , Aruta Giustina , Esposito Augusto , Del Vecchio Blanco Francesca , Piluso Giulio , Nigro Vincenzo , Scarano Gioacchino , Limongelli Giuseppe 
Published: September 2023

AbstractAymé‐Gripp Syndrome (AGS) is an ultra‐rare syndrome characterized by peculiar facial traits combined with early bilateral cataracts, sensorineural hearing loss, and variable neurodevelopmental abnormalities. Only a few cases carrying a pathogenic variant in MAF have been described to date. A significant effort is then required to expand the genotypic and phenotypic spectrum of this condition. In this paper, we report the peculiar case of a 6‐year‐old girl carrying a de novo missense pathogenic variant in MAF, being the first case reported to show a milder phenotype with no cataracts and deafness displayed. Furthermore, we performed a systematic review of previously published cases, focusing on clinical manifestation and genotype.
Copper‐Catalyzed Asymmetric Acylboration of 1,3‐Butadienylboronate with Acyl Fluorides
Authors: Gao Shang , Liu Jiaming , Troya Diego , Chen Ming 
Published: September 2023

AbstractWe report herein a Cu‐catalyzed regio‐, diastereo‐ and enantioselective acylboration of 1,3‐butadienylboronate with acyl fluorides. Under the developed conditions, the reactions provide (Z)‐β,γ‐unsaturated ketones bearing an α‐tertiary stereocenter with high Z‐selectivity and excellent enantioselectivities. While direct access to highly enantioenriched E‐isomers was not successful, we showed that such molecules can be synthesized with excellent E‐selectivity and optical purities via Pd‐catalyzed alkene isomerization from the corresponding Z‐isomers. The orthogonal chemical reactivities of the functional groups embedded in the ketone products allow for diverse chemoselective transformations, which provides a valuable platform for further derivatization.
Aldol Condensation for the Construction of Organic Functional Materials
Authors: Zhu Xiuyuan , Duan Jiayao , Chen Junxin , Liu Riping , Qin Ze , Chen Hu , Yue Wan 
Published: September 2023

AbstractAldol condensation is a cost‐effective and sustainable synthetic method, offering the advantages of low complexity, substrate universality, and high efficiency. Over the past decade, it has become popular for creating next‐generation organic functional materials, particularly rigid‐rod conjugated (semi)conductors. This review focuses on conjugated small molecules, oligomers, and polymeric (semi)conductors synthesized through aldol condensation, with emphasis on their remarkable features in advancing n‐type organic field‐effect transistors (OFETs), organic electrochemical transistors (OECTs), organic photovoltaics (OPVs), and organic thermoelectrics (OTEs) as well as NIR‐II photothermal conversion. Coherence character, optical properties, microstructure, and chain conformation are investigated to understand material‐property relationships. Future applications and challenges in this area are also discussed.
Relative Local Electron Density Tuning in Metal‐Covalent Organic Frameworks for Boosting CO2Photoreduction
Authors: Zhang Mi , Huang Pei , Liao Jia‐Peng , Yang Ming‐Yi , Zhang Shuai‐Bing , Liu Yu‐Fei , Lu Meng , Li Shun‐Li , Cai Yue‐Peng , Lan Ya‐Qian 
Published: September 2023

AbstractThe high local electron density and efficient charge carrier separation are two important factors to affect photocatalytic activity, especially for the CO2photoreduction reaction. However, the systematic studies on the structure‐functional relationship regarding the above two factors based on precisely structure model are rarely reported. Herein, as a proof‐of‐concept, we developed a new strategy on the evaluation of local electron density by controlling the relative electron‐deficient (ED) and electron‐rich (ER) intensity of monomer at a molecular level based on three rational‐designed vinylene‐linked sp2carbon‐covalent organic frameworks (COFs). As expected, the as‐prepared vinylene‐linked sp2carbon‐conjugated metal‐covalent organic framework (MCOFs) (VL‐MCOF‐1) with molecular junction exhibited excellent activities for CO2‐to‐HCOOH conversion (283.41 μmol g−1 h−1) and high selectivity of 97.1 %, much higher than the VL‐MCOF‐2 and g‐C34N6‐COF, which is due to the synergistic effect of the multi‐electronic metal clusters (Cu3(PyCA)3) (PyCA=pyrazolate‐4‐carboxaldehyde) as strong ER roles and cyanopyridine units as ED roles and active sites, as well as the boosted photo‐induced charge separation efficiency of vinyl connection and increased light utilization ability. These results not only provide a strategy for regulating the electron‐density distribution of photocatalysts at the molecular level but also offers profound insights for metal clusters‐based COFs to effective CO2conversion.
Function of revolute zygapophyses in the lumbar vertebrae of early placental mammals
Authors: Kort Anne E. , Jones Katrina E. 
Published: September 2023

AbstractThe unique morphology of mammalian lumbar vertebrae allows the spine to flex and extend in the sagittal plane during locomotion. This movement increases stride length and allows mammals to efficiently breathe while running with an asymmetric gait. In extant mammals, the amount of flexion that occurs varies across different locomotor styles, with dorsostable runners relying more on movement of long limbs to run and dorsomobile runners incorporating more flexion of the back. Although long limbs and a stabilized lumbar region are commonly associated with each other in extant mammals, many “archaic” placental mammals with short limbs had lumbar vertebrae with revolute zygapophyses. These articulations with an interlocking S‐shape are found only in artiodactyls among extant mammals and have been hypothesized to stabilize against flexion of the back. This would suggest that archaic placental mammals may not have incorporated dorsoventral flexion into locomotion to the same extent as extant mammals with similar proportions. We tested the relative mobility of fossil lumbar vertebrae from two early placental mammals, the creodonts Patriofelis and Limnocyon, to see how these vertebrae may have functioned. We compared range of motion (ROM) between the original vertebrae, with revolute morphology and digitally altered vertebrae with a flat morphology. We found that the revolute morphology had relatively little effect on dorsoventral flexion and instead that it likely prevented disarticulation due to shear forces on the spine. These results show that flexion of the spine has been an important part of mammalian locomotion for at least 50 million years.
Proprioceptive innervation of the human lips
Authors: Martín‐Cruces José , Cuendias Patricia , García‐Mesa Yolanda , Cobo Juan L. , García‐Suárez Olivia , Gaite Juan J. , Vega José A. , Martín‐Biedma Benjamín 
Published: September 2023

AbstractThe objective of this study was to analyze the proprioceptive innervation of human lips, especially of the orbicularis oris muscle, since it is classically accepted that facial muscles lack typical proprioceptors, that is, muscle spindles, but recently this has been doubted. Upper and lower human lips (n = 5) from non‐embalmed frozen cadavers were immunostained for detection of S100 protein (to identify nerves and sensory nerve formations), myosin heavy chain (to label muscle fibers within muscle spindles), and the mechano‐gated ion channel PIEZO2. No muscle spindles were found, but there was a high density of sensory nerve formations, which were morphologically heterogeneous, and in some cases resemble Ruffini‐like and Pacinian sensory corpuscles. The axons of these sensory formations displayed immunoreactivity for PIEZO2. Human lip muscles lack typical proprioceptors but possess a dense sensory innervation which can serve the lip proprioception.
Regioselective Synthesis of 3‐Substituted Isocoumarin‐1‐imines via Palladium‐Catalyzed Denitrogenative Transannulation of 1,2,3‐Benzotriazin‐4(3H)‐ones and Terminal Alkynes
Authors: Balakrishnan Madasamy Hari , Sureshbabu Popuri , Korivi Ramaraju , Mannathan Subramaniyan 
Published: September 2023

AbstractA palladium‐catalyzed denitrogenative transannulation strategy to access various 3‐substituted isocoumarin‐1‐imine frameworks using 1,2,3‐benzotriazin‐4(3H)‐ones and terminal alkynes is described. The reaction is highly regioselective and tolerates a wide range of functional groups. The reaction is believed to proceed via a five‐membered palladacycle intermediate extruding environmentally benign molecular nitrogen as a by‐product. The utility of this method was showcased through the one‐pot synthesis of biologically relevant 3‐substituted isocoumarin scaffolds.
Synthesis of Naphthalene‐ and Phenanthrene‐Fused Smaragdyrins and Their BF2Complexes
Authors: Liu Pingting , Wang Kaisheng , Xu Ling , Rao Yutao , Zhou Mingbo , Osuka Atsuhiro , Song Jianxin 
Published: September 2023

AbstractNaphthalene‐ and phenanthrene‐fused [22]smaragdyrin BF2‐complexes were synthesized by 1) Suzuki‐Miyaura coupling ofβ‐brominated [22]smaragdyrin BF2complexes with 2‐formylarylboronates, 2) Witting‐type methoxymethylenation of the formyl group, and 3) methanesulfonic acid‐catalyzed cyclization reaction. Subsequently these BF2complexes were deboronized and oxidized to the corresponding antiaromatic [20]smaragdyrin free bases. The installed fused structures led to decrease of the aromatic characters of the [22]smaragdyrin BF2complexes and the antiaromatic characters of the [20]smaragdyrin free bases.