bluuebunny/crossref_metadata_2025_split huggingface dataset:
Are more retractions due to more scrutiny?
Authors: Brembs Björn 
Published: August 2023

In the last “Science Weekly” podcast from the Guardian, the topic was retractions. At about 20:29 into the episode, Hannah Devlin asked, whether the reason ‘top’ journals retract more articles may be because of increased scrutiny there. The underlying assumption is very reasonable, as many more eyes see each paper in such journals and the motivation to shoot down such high-profile papers might also be higher.
The Willgerodt-Kindler Reaction: mechanistic reality check 3. A peek under the hood for transition state location.
Authors: Rzepa Henry 
Published: August 2023

The two previous surveys of the potential energy surface for this, it has to be said, rather obscure reaction led to energy barriers that were rather to high to be entirely convincing. So here is a third possibility. The red section corresponds to the previous exploration, in which a 3-membered sulfur ring intermediate was mooted. Here we go back to a 3-ring with nitrogen instead.
Non-covalent-interaction (NCI) surfaces for two large annulenes (revisited).
Authors: Rzepa Henry 
Published: August 2023

The last post addressed the concept of “steric clashes” in a pericyclic reaction transition state as an extension of the time honoured practice of building molecular models to analyse reaction outcomes. A modern computer generated model might express this in terms of a NCI (non-covalent-interaction) surface.
Please address these concerns before we can accept your #OA proposal
Authors: Brembs Björn 
Published: August 2023

Below, I’ve taken the liberty to “peer-review” recent proposals to ‘flip’ subscription journals to open access The applicants have provided an interesting proposal of how to ‘flip’ the current subscription journals to an article processing charges (APC)-based ‘gold’ open access […] ↓ Read the rest of this entry...
Dimethyl ketal hydrolysis catalysed by hydroxide and hydronium ions
Authors: Rzepa Henry 
Published: August 2023

In the preceding post, I looked at a computed mechanism for the hydrolysis of a ketal by water. Of course, pure water consists of three potential catalysts, water itself or [H
<sub>
2
</sub>
O], and the products of autoionisation, [OH
<sup>
–
</sup>
] and [H
<sub>
3
</sub>
O
<sup>
+
</sup>
]. The latter are in much smaller concentration, equivalent to a penalty of ~11.9 kcal/mol on any free energy barrier.
Um estudo sobre a consciência em Kierkegaard
Authors: Protasio Myriam Moreira 
Published: August 2023

Este texto visa estabelecer um percurso na obra de Søren Kierkegaard sobre a questão da consciência. Vamos partir da verdade e da dúvida no texto Johannes Climacus ou É preciso duvidar de tudo. Em seguida consideraremos alguns textos da obra Ou...Ou, finalizando com considerações acerca do eu em Doença até a morte, assinada pelo pseudônimo Anticlimacus. Desta forma, estaremos apresentando um estudo inicial acerca da problemática da consciência em Kierkegaard. Referências bibliográficasFERRO, Nuno. Estudos sobre Kierkegaard. São Paulo: LiberArs, 2012.FONNEGRA, Sérgio Muñoz. “La ética em la formación de la personalidad”, Revista Portuguesa de Filosofia: Horizontes existenciários da filosofia de Søren Kierkegaard and Philosophy Today,v. LXIV, n. 2-4, 2008, p. 131 -- 147.KEARNEY, Richard. “Deus após Deus: uma tentativa anateísta de reimaginar Deus”. Trad. Maria Helena Silvia Soares. Ekstasis: revistade hermenêutica e fenomenologia, v. IV, n. 2, 2015, p. 214 -- 229.KIERKEGAARD, Søren Aybe. Ponto de Vista explicativo da minha obra como escritor. Trad. João Gama. Porto: Edições 70, 1996._____. Johannes Climacus ou É preciso duvidar de tudo. Trad. Silvia Saviano Sampaio e Álvaro Luiz Montenegro Valls. São Paulo: Martins Fontes, 2003._____. O lo uno o lo outro: um fragmento de vida I.Trad. Dario Gonzalez. Madrid: Editorial Trotta, 2006._____. “Los estádios eróticos inmediatos, o el erotismo musical” In: KIERKEGAARD, Søren Aybe, O lo uno o lo outro: um fragmento de vida I.Trad. Dario Gonzalez. Madrid: Editorial Trotta, 2006a, p. 71 a 155._____. “Diario del Seductor” In KIERKEGAARD, Søren Aybe, O lo uno o lo outro: um fragmento de vida I.Trad. Dario Gonzalez. Madrid: Editorial Trotta, 2006b, p. 309-439._____. O lo uno o lo outro: um fragmento de vida II. Trad. Dario Gonzalez. Madrid: Editorial Trotta, 2007._____. “El equilibrio entre ló estético y lo ético en la formación de la personalidad” In: KIERKEGAARD, Søren Aybe, O lo uno o lo outro: um fragmento de vida II.Trad. Dario Gonzalez. Madrid: Editorial Trotta, 2007a, p. 147-297._____. A Repetição. Trad. José Miranda Justo. Lisboa: Relógio D'Água Editores, 2009._____. Temor e Tremor. Trad. Elisabete M. de Sousa. Lisboa: Relógio D'Água Editores, 2009a._____. Desespero Humano - doença até a morte.Trad. Adolfo Casais Monteiro. São Paulo: Editora Unesp, 2010._____. O Conceito de Angústia. Trad. Álvaro Luiz Montenegro Valls. Petrópolis, RJ: Vozes; São Paulo, SP: Editora Universitária São Francisco, 2010a._____. Ou -- Ou Um fragmento de Vida (Primeira parte). Trad. Elisabete M. de Sousa. Lisboa: Relógio D'Água Editores, 2013. LAFARGE, Jacques. “Prefácio” In: KIERKEGAARD, Søren Aybe, Johannes Climacus ou É preciso duvidar de tudo. Trad. Silvia Saviano Sampaio e Álvaro Luiz Montenegro Valls. São Paulo: Martins Fontes, 2003, p. V-XXVI.
Incidence of Sacroiliac Screw Implant Pain and Results of Screw Removal
Authors: Gurnea Taylor P , Gonzalez Miguel A , Turner Alexander R , Moody Alastair E , Althausen Peter 
Published: August 2023

Introduction: Percutaneous sacroiliac(SI) screw fixation of pelvic fractures has become commonplace. Routine removal of SI screws has been recommended by some physicians while others remove only symptomatic implants citing risks associated with this procedure. Few publications exist documenting the incidence of SI screw related hardware pain, rates of SI screw removal, the results of implant removal and the risks and complications associated with this procedure. Our objective is to document the incidence and clinical impact of symptomatic sacroiliac drew removal at a community level II trauma centers over a 12-year period. Methods: Operative records were queried to identify 250 patients with pelvic ring injuries treated with SI screw placement at our institution. Records were analyzed to identify fracture classification, implant removal, reason for implant removal, analogue pain scales before and after implant removal and complications after implant removal. Results: During the 12 year study period from 2006-2018, 300 posterior pelvic ring screws were placed in 250 patients. 46/250 (18.4%) patients underwent implant removal, accounting for 66 screws. 43 patients cited painful hardware as the reason for removal and 3 patients cited infection. Average time to removal was 6.7 months. Mean analog pain scales were 4.91 and 0.51 before and after removal respectively. No intra-operative or post-operative complications were encountered. All patients reported improvement in pain with screw removal Conclusions: Postoperative pain following SI screw placement attributed to retained implant occurs in 18% of patients. Despite the previously documented proximity of neuromuscular structures, no intra-operative or postoperative complications were observed in patients who underwent screw removal. All patients reported significant relief of symptoms following implant removal. In patients experiencing pain following SI screw placement, screw removal 6 months following initial fixation is a safe and effective procedure.
Wound complications, infections and nonunions do not increase with open reduction of tibia shaft fractures treated with intramedullary devices
Authors: Will Ryan 
Published: August 2023

Introduction: Tibia shaft fractures on common injuries and commonly treated with intramedullary implants. The effect of open reduction on fracture healing and wound healing is not well described. Methods: A retrospective chart review of 32 cases of open or closed tibia shaft fractures treated by a single surgeon at a Level 3 trauma center with open reduction and use of an intramedullary implant. Re-operation rates for any reason, deep and superficial infection rate and fracture healing were recorded. Results: All 32 patients healed their fractures and 4 patients require removal of painful hardware. Two cases superficial infection occurred, and no cases of deep infection occurred. Conclusion: Open reduction of tibia shaft fractures can be done safely and effectively using appropriate technique in a diverse set of patients that present in a community type setting.
Management of a Lateral Meniscus Tear with Bucket-Handle Displacement in a Seven-Year-Old with Lateral Discoid Meniscus Morphology: A Case Report
Authors: Combs Kristen , Soppe Clint , Muffly Matthew 
Published: August 2023

Background: Lateral meniscus tears in patients less than ten years old are exceedingly rare. Displaced bucket handle tears of the lateral meniscus are even less commonly encountered. Hypothesis/Purpose: This case report details the presentation, treatment, and recovery of a seven year old female who presented with a bucket handle lateral meniscus tear and was found to have underlying discoid meniscus morphology. Methods: This case report details the pre-operative, arthroscopic findings, repair technique, and post-operative outcome of a single patient presenting with a rare injury pattern. Results: The lateral meniscus was torn along the periphery at the meniscocapsular junction involving zones I-III with displacement into the notch. The meniscal tissue appeared hypertrophied and was noted to be a Wrisberg type discoid variant. A saucerization and repair was performed using sutures utilizing a combination of all-inside and outside-in repair techniques. The patient regained full range of motion and returned to full unimpeded activity at three months post-operatively. Conclusions: This is a unique case of a pediatric patient less than ten years old presenting with a bucket-handle tear of a discoid lateral meniscus who underwent surgical repair. The case details the saucerization and repair technique with successful recovery of this pediatric patient to date. It highlights a technique for meniscus repair in lieu of partial meniscectomy which is of particular benefit in the pediatric population.
Multicenter Survey of Resident Education in Professional Development and the Business of Orthopaedics: Are Residents Ready for Transition to Practice?
Authors: Vallier Heather , Sagi Henry Claude , Quinnan Stephen , Obremskey William , Meinberg Eric , Mauffrey Cyril , Whiting Paul , Kweon Chris , Only Arthur , Okelana Bandele , Flagstag Ilexa , Vang Sandy , Ghasem Alexander , Friess Darin , Parikh Harsh , Blaschke Breanna , Gorman Tiffany , Bhatt Etasha , Cunningham Brian 
Published: August 2023

Background Systems-based practice is a core competency of orthopaedic residency, yet there is no defined curriculum to address this area, which may leave residents with gaps in knowledge. Objective The aim of this study was to assess residents’ understanding of systems-based practice and interest in incorporating these principles into curricula. Methods In 2018 a survey was emailed to residents in programs across the United States evaluating comprehension in systems-based practice, and interest in specific domains of curriculum development: personal finance, value of orthopaedics, practice dynamics, transition to practice, work life balance, research, professional development, leadership development, international medical work, and law. Residents were categorized into subgroups based on years of training: junior (1-3) and senior (4-5), and nonparametric chi-squared analysis was performed between the groups. Results Of 275 residents surveyed, 151 completed the survey for an overall response rate of 55%. Self-rated understanding of systems-based practice was statistically identical (p=1.00) between junior and senior residents; 91.4% of both groups indicated low comprehension of the systems-based practice competency. There was strong interest by the majority of respondents in further training in many domains. When subcategorized as junior and senior residents, the only significant differences in interest were in professional development (p=0.04) and transition to practice (p = 0.01) domains, with more junior residents expressing strong interest in further training in these topics. Conclusions This study indicated that there is a gap in resident education in systems-based practice and that orthopaedic residents are interested in the enhancement of education in this domain.
The Impact of the COVID-19 Pandemic on Physicians’ Perception of Digital Health in Orthopedics
Authors: McGrath Mikayla , Spira Bronwyn , Grady-Benson John , Bruning Paul , Kress Kenneth , Belniak Robert , Golladay Gregory J , Damodar Dhanur 
Published: August 2023

Digital health and technology have been growing in healthcare over the past 10 years as they have allowed for health systems to remotely deliver virtual care at scale. Despite this, providers and healthcare systems have traditionally viewed technology as an additional asset, or even a burden in some cases, rather than a necessity. Due to the impact of COVID-19 on in-person treatment options for millions of patients, a rapid adoption of telemedicine and virtual healthcare services has been seen across the country and the globe. A survey (Appendix A) was conducted that included respondents from all roles within leading healthcare organizations - from surgeons to nurses to administrators & more. By analyzing data from various healthcare personas, we aimed to paint a complete picture of the orthopedic healthcare industry. COVID-19 has challenged the healthcare system and physicians to reimagine the ways they have traditionally delivered care to patients. While barriers to adoption exist – including reimbursement and operational efficiencies – the orthopedic community is on track to have virtual care and telemedicine as a new normal long after the pandemic has come to an end. Forward-thinking healthcare systems and physician groups that rise to the challenge and adapt to this change will continue to make strides in improving patient care and driving this forward momentum, wherein healthcare can be a true hybrid of virtual and in-person care that best suits the needs of all patients.
Immediate Weight Bearing After Fixation of Humeral Shaft Fractures with Small Fragment Hybrid Plating: A Biomechanical Analysis
Authors: Bledsoe J. Gary , Geraud Simone , Cannada Lisa K. 
Published: August 2023

Background This study evaluates the stiffness of both 4.5 mm dynamic compression plates (DCP) and 3.5 mm hybrid locking-compression plates (LCP) for treatment of humeral shaft fractures in a simulated weight bearing model. Methods Testing was performed on 16 4th generation Sawbones humeri. Initial axial and torsional stiffness were determined. Plates were placed and a 5 mm defect was produced. Specimens were subjected to 90,000 loading cycles to simulate 90 days of crutch walking and then loaded to failure. Statistical analysis was performed using a t-test with significance at P < 0.05. Findings Comparison reveals a significant difference between the intact axial and torsional stiffness of 4.5 mm DCPs and 3.5 mm LCPs. The 3.5 mm plates provided 80% of the axial stiffness and 75% of the torsional stiffness of the 4.5 mm plates. The 3.5 mm plated bones failed at 79% of the mean failure load of the 4.5 mm plated bones. The 3.5 mm plated bones failed due to incidental torsion during axial loading; the 4.5 mm plated bones failed as a result of gap closure. Interpretation Our results followed expectations due to differences in plate dimensions. There were no apparent differences between constructs following cyclic loading. Our model includes a fracture gap, which requires the plate to carry the entire load. This does not simulate the actual clinical scenario wherein healing would tend to improve construct performance. While the constructs performed differently, both appear to support loads that are anticipated in the clinical setting.
Ambulatory Hip and Knee Replacement Outcomes During COVID-19 Outbreak in Washington State
Authors: Jabbouri Sahir , Jones Brett , Song Christian , Dasa Vinod , McAllister Craig 
Published: August 2023

Introduction The first case of COVID-19 in the U.S. was diagnosed on January 19th, 2020 in Washington State and evidence suggested that the virus was circulating in Washington prior to this. Elective joint replacements were suspended on March 19th, 2020 with the goal of preserving resources and protecting patients and workers. This pilot study evaluates a group of patients who underwent elective joint replacement during the initial surge of COVID-19 and before the shutdown of elective surgeries to examine the patient experience of elective joint arthroplasty during a COVID-19 surge. All patients participated in an outpatient joint replacement program utilizing a dedicated patient engagement platform which enabled the investigation of Patient Reported Outcome Measures (PROMs), COVID-19 surveys, as well as patient satisfaction outcomes. Methods This observational study reviewed 282 patients who underwent hip and knee arthroplasty in Washington State during the COVID-19 surge between January and March 2020. Surgeries were done by surgeons experienced in outpatient techniques using a standardized protocol. Patients registered on a dedicated cloud platform (The SwiftPath Program, LLC). Patient education emphasized the benefits of early discharge and recovery at home. The patient experience included shared-decision-making and a vetted risk stratification algorithm. Homecare monitoring allowed for notifications to the care team as well as opiate tracking, recovery milestones, and PROs. Patients responded to postoperative homecare queries, satisfaction surveys, and standardized PROs surveys (HOOS JR., KOOS JR., PROMIS) at baseline and routine post-op intervals out to 6 weeks. A follow-up “COVID-19 survey” was also used to specifically evaluate exposure to and complications from potential COVID-19 infection. Results There were 254 patients out of 282 (90.0%) who registered and had partially completed the data collection. The average age of patients was 67.7 years old (range 30 – 91). Fifty-nine patients (23.2%) completed HOOS JR. and KOOS JR. data, and of these patients, 46 were knee replacements, and 13 were hip replacements. Every patient who responded both to the preoperative and postoperative HOOS JR. and KOOS JR. questionnaires had improved scores by six weeks postoperatively. Of the 180 patients who responded to the COVID-19 survey, none reported viral symptoms or developed COVID-19. Patients indicated limited physical therapy access, but recovery was not impacted. The average surgery satisfaction during the pandemic was 9.3/10.0. Conclusion An online patient engagement platform can help monitor the clinical course, PROs as well as any virus-related illnesses in patients undergoing TJA. Information from PROs can be used to evaluate outcomes during a pandemic. Additional studies should focus on larger numbers of patients and compare PROs with clinical outcomes to help document the safety of performing elective surgeries during pandemics.
Complete Traumatic Laceration of the Sciatic Nerve Secondary to Acetabular Fracture: A Case Report
Authors: John Mitchell , Taylor Shea , Ahmed Adil , Mir Hassan 
Published: August 2023

BACKGROUND Sciatic nerve injury in acetabular fractures is a rare event, with the majority of cases being transient neuropraxias. To date there are no published cases of complete traumatic sciatic nerve lacerations due to acetabular fracture with associated hip dislocation. We describe a case of such an event confirmed at the time of acetabular fracture fixation. CASE PRESENTATION The patient was a 37-year-old polytraumatized victim involved in a motor vehicle accident who presented with multiple injuries including left acetabular fracture with associated femoral head dislocation. The patient had absent function of both divisions of the sciatic nerve on initial evaluation. She was hemodynamically unstable on arrival requiring multidisciplinary intervention and transfer to the intensive care unit after temporization of her multiple system injuries. Following adequate resuscitation and improved hemodynamic status she was taken to the operating room for definitive orthopaedic fixation of her pelvis, acetabulum, and multiple long bones. Intraoperatively the sciatic nerve was identified, found to be completely lacerated. Direct repair was performed. Following discharge to a long term rehabilitation facility on post-trauma day 53 she was lost to follow up for 6 months when she presented to the emergency department for abdominal pain. Her pelvic and acetabular hardware was radiographically stable showing fracture union, and her lower extremity neurological examination was unchanged from her preoperative exam. CONCLUSION Injury to the sciatic nerve associated with pelvic and acetabular trauma is relatively rare and is most often neuropraxic. To our knowledge there is no reports in the literature on complete lacerations in this context, and there is a paucity in the literature on managing such injuries. Orthopaedic traumatologist must be aware of the possibility of this presentation in order to manage it appropriately and counsel patients accordingly.
Percutaneous Coracoclavicular Tightrope Reduction of a Displaced Distal Clavicular Fracture: A Case Report
Authors: Yang Xiuyi A. , Vermeijden Harmen D. , O'Brien Robert , Van der List Jelle P. , Difelice Gregory S. 
Published: August 2023

Case A 34-year-old male presented with a Neer type IIa clavicle fracture after a direct fall on the right shoulder following a cycling accident. The patient subsequently underwent percutaneous reduction and fixation with a coracoclavicular TightRope. The postoperative course was uncomplicated, and radiographic union was noted at 12 weeks postoperatively. The patient reported no further complaints with full range of motion of his shoulder and had a QuickDASH, SANE, ASES, and Constant Murley score of 100 at one year post-operatively. Conclusion Neer type II clavicle fractures can be notoriously unstable when managed non-operatively. Although multiple treatment modalities have been utilized, there remains some debate regarding the optimal surgical approach. Due to its minimally invasive nature and avoiding the risk for future hardware removal, coracoclavicular TightRope placement might be an excellent treatment option for patients with distal clavicle fractures.