bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigation of the low‐temperature properties and oil resistance of peroxide‐cured epichlorohydrin rubber and nitrile butadiene rubber blends
Authors: He Chunjiang , Gao Ming , Chen Chuanzhi , Ji Yuan , Zhao Jingcun , Pei Dingfeng , Wang Wei 
Published: August 2023

AbstractLow‐acrylonitrile nitrile butadiene rubbers (NBRs) are seriously degraded by No. 15 oil in the hydraulic system of aircraft. The present work aims to prepare rubber materials with excellent low‐temperature and No. 15 aviation hydraulic oil resistance. Terpolymerization epichlorohydrin rubber (ECO) and low‐acrylonitrile NBR were blended. The blends were vulcanized using peroxide. The effects of the ECO/NBR blending ratio on the oil resistance and low‐temperature, physical and mechanical, hot air aging, and ozone aging properties were investigated using a multitechnique approach. The results showed that ECO had double bonds and could be vulcanized by peroxide. The percentage of volume swelling of ECO in No. 15 oil was about 1/7 of that of NBR. As the ECO content increased, the oil and ozone resistance and brittle temperature were gradually improved. The coefficient of cold resistance under compression and glass transition temperature peaked at a ratio of 50/50 due to the migration of dicumyl peroxide from ECO to NBR. Further, vulcanization, hot air aging, and other physical properties are also discussed. This work provides a reference for the development of ultra‐low‐temperature performance and No. 15 oil‐resistant sealing rubber materials.Highlights
ECO EPION 301 could be cured by peroxide.
The blends of ECO and low‐acrylonitrile NBR could be cured by peroxide.
The blends exhibited better oil resistance and low‐temperature performance.
Some dicumyl peroxide migrated from ECO to NBR in the blends.
Obviously Enhanced Fluorescent Signal of Core‐Shell Nanostructures through Simultaneous Regulation of Spectral Overlap and Shell Thickness for Imaging and Photothermal Therapy of Ovarian Cancer Cells
Authors: Li Xianyang , Huang Jingyuan , Wu Xin , Piao Xianling , Lv Danning , Zhang Gude , Ahn Dong June , Cui Chunzhi 
Published: August 2023

AbstractIn this research, by simultaneously regulating the two major factors affecting the plasmonic enhanced fluorescence (PEF), spectral overlap and the distance between the fluororophores and the noble metal nanoparticles, a significantly enhanced fluorescent signal is achieved. Core‐shell nanostructures composed of aspect ratio (AR) adjustable gold nanorods (GNRs) and various thickness of SiO2 are prepared and the decorated fluorophores are realized optimized PEF. A typical stimuli‐responsive conjugated polymer, polydiacetylene (PDA), and a near‐infrared (NIR) dye Cy5.5 are selected as fluorophores and their fluorescent signal are enhanced 7.26 and 4.41 times, respectively. Based on the optimized optical properties, a multifunctional antibody modified Mab‐Cy5.5‐GNRs@SiO2 is successfully demonstrated the targeting, imaging, and photothermal therapy (PTT) effects on SKOV‐3 ovarian cancer cells.
Improving mass accuracy in matrix‐assisted laser desorption ionization time‐of‐flight mass spectrometry analysis of pathogenic proteins using 6xHIS‐tagged internal calibration
Authors: Lee Saeyoung , Park Ju‐Ri , Hwang Seohyun , Yang Won Suk , Baek Je‐Hyun 
Published: August 2023

RationaleLinear mode of matrix‐assisted laser desorption ionization time‐of‐flight mass spectrometry (MALDI‐TOFMS) has been routinely used for bacterial identification in the clinic, depending on the pattern analysis of spectral libraries rather than accurate mass measurement of ribosomal proteins (10–15 kDa). However, a demand for more accurate mass analysis of pathogens (e.g. KPC‐2 carbapenemase) has been recently increasing for diagnostic purposes.MethodsWe introduced a 6xHIS‐tagged KPC‐2 (i.e. hKPC‐2) and used it as an internal mass calibrator for the mass calibration of target proteins. After internal mass calibration (In‐Cal), we evaluated the observed mass of KPC‐2 against the theoretical mass of hKPC‐2, which has 823 Da mass difference from the target protein. We further assessed the accuracy and precision of our calibration method regarding the identification of KPC‐2 and other pathogens in clinical isolates (n = 42).ResultsAmong several candidates for internal mass calibrators, the In‐Cal using a 6xHIS‐tagged protein on the target showed the highest mass accuracy and precision in the detection of target proteins (e.g. KPC‐2). The application of hKPC‐2 as an internal calibrator showed substantial improvement of mass accuracy, mass precision and also quantification of KPC in linearity and repeatability for KPC detection in the clinical isolates.ConclusionsOur In‐Cal method using 6xHIS‐tagged protein in MALDI‐TOFMS allows successful mass calibration (<3.5 Da) of pathogenic proteins (>20 kDa) and provides high mass accuracy as much as that of medium‐ and high‐resolution mass spectrometry.
Deep learning‐based training data augmentation combined with post‐classification improves the classification accuracy for dominant and scattered invasive forest tree species
Authors: Likó Szilárd Balázs , Holb Imre J. , Oláh Viktor , Burai Péter , Szabó Szilárd 
Published: August 2023

AbstractSpecies composition of forests is a very important component from the point of view of nature conservation and forestry. We aimed to identify 10 tree species in a hilly forest stand using a hyperspectral aerial image with a particular focus on two invasive species, namely Ailanthus tree and black locust. Deep learning‐based training data augmentation (TDA) and post‐classification techniques were tested with Random Forest and Support Vector Machine (SVM) classifiers. SVM had better performance with 81.6% overall accuracy (OA). TDA increased the OA to 82.5% and post‐classification with segmentation improved the total accuracy to 86.2%. The class‐level performance was more convincing: the invasive Ailanthus trees were identified with 40% higher producer's and user's accuracies (PA and UA) to 70% related to the common technique (using a training dataset and classifying the trees). The PA and UA did not change in the case of the other invasive species, black locust. Accordingly, this new method identifies well Ailanthus, a sparsely distributed species in the area; while it was less efficient with black locust that dominates larger patches in the stand. The combination of the two ancillary steps of hyperspectral image classification proved to be reasonable and can support forest management planning and nature conservation in the future.
Phosphorus availability and corn (Zea mays L.) response to application of P‐based commercial organic fertilizers to a calcareous soil
Authors: Kodaolu Busayo , Mohammed Ibrahim , Gillespie Adam W. , Audette Yuki , Longstaffe James G. 
Published: August 2023

AbstractRecycling of organic wastes for agricultural production has been recommended as a sustainable way to close the phosphorus (P) cycle. This study seeks to characterize the P forms in organic fertilizers derived from agricultural and nonagricultural source materials to understand how these organic fertilizers will affect corn growth and soil available P. Organic fertilizers including turkey litter compost (TLC), biosolid pellets (BSP), and source separated organic compost (SSO) were applied to a sandy loam soil and compared to controls that received no nutrients or chemical fertilizer. Results from sequential chemical extractions and X‐ray absorption near edge structure spectroscopy revealed that most of the P species are inorganic, with SSO and TLC containing primarily Ca‐P and Mg‐P forms, while the P in the BSP treatments was mostly associated with aluminium (Al). The two chemical fertilizer treatments had the greatest impact on corn height at the initial growth stage; however, after 42 days, corn height was similar for the organic fertilizers and chemical treatment. This initial slow response from the organic fertilizer treatments reduced the grain yield compared to chemical treatment. The results of this study suggest that priority should be given to sufficient P availability at the initial growth stage. Overall, organic fertilizer is a promising P source for grain crop production, but calibration and correlation studies are needed to ensure optimum supply of P for the initial growth stage.
Coupled effect of waste glass powder and glass fibers on mechanical properties of concrete: A step towards the elimination of non‐biodegradable waste
Authors: Ahmed Tauqir , Ali Muhammad , Akmal Usman , Aslam Fahid , Abbass Wasim , Aziz Mubashir , Hamza Muhammad , Shah Ihsanullah , Shah Hammad Ahmed 
Published: August 2023

AbstractSilica, a principal component of waste glass powder (GP) reacts with calcium hydroxide to form the hydration products, and the process is affected by the fineness of GP and the percentage of cement replaced. This study investigates the structural behavior of concrete incorporating GP in reinforced concrete members by 0%–25% (by weight) replacement of cement with GP along with 0%–0.45% addition of glass fibers (GFs). The compressive and tensile strengths, strength activity index (SAI), and failure mode of treated concrete mixtures have revealed the optimum values as 15% replacement of cement with GP with 0.3% of GF. In the second stage of experiment, reinforced concrete beams were cast at various percentages of GP and GF to investigate the load–deflection response. It was observed that the beam specimen treated with GP exhibited considerably less mid‐span deflection (14.8 mm) at failure as compared to the control beam (with no GP and GF) which failed at 29.4 mm. The beam specimen treated with GP only showed significant degradation in stiffness after the peak load due to the fact that a part of GP remains unreacted and acts as a filler. Moreover, the beam specimen cast at optimum percentages of GP (15%) and GF (0.3%) showed large mid‐span deflection and higher failure load as compared to the control beam. These results suggest that the partial replacement of cement with GP should be accompanied by the addition of fibers to avoid unwanted brittle responses of GP concrete, with the additional advantage of reducing the non‐biodegradable waste.
Genes associated with N6‐methyladenosine regulators provide insight into the prognosis and immune response to renal clear cell carcinoma
Authors: Fan Guobin , Wu Dejun , Chen Huaping , Wen Zhi , Liao Linhui , He Shuming , Yang Jie 
Published: August 2023

AbstractAs one of the most common messenger ribonucleic acid modifications in eukaryotic organisms, N6‐methyladenosine (m6A) is involved in a wide variety of biological functions. The imbalance of m6A RNA modification may be linked to cancer and other disorders, according to a growing body of studies. Its effects on clear cell renal cell carcinoma (KIRC) have not been well discussed, though. Here, we acquired the expression patterns of 23 important regulators of m6A RNA modification and assess how they might fare in KIRC. We observed that 17 major m6A RNA modification regulatory factors had a substantial predictive influence on KIRC. Using the “ConsensusCluster” program, we defined two groupings (Cluster 1 and Cluster 2) depending on the expression of the aforementioned 17 key m6A RNA methylation regulators. The Cluster 2 has a less favorable outcome and is strongly related with a lesser immune microenvironment, according to the findings. We also developed a strong risk profile for three m6A RNA modifiers (METTL14, YTHDF1, and LRPPRC) using multivariate Cox regression analysis. According to further research, the aforementioned risk profile could serve as an independent predicting factor for KIRC, and the chemotherapy response sensitivity was analyzed between two risk groups. Moreover, to effectively forecast the future outlook of KIRC clients, we established a novel prognostic approach according to gender, age, histopathological level, clinical stage, and risk score. Finally, the function of hub gene METTL14 was validated by cell proliferation and subcutaneous graft tumor in mice. In conclusion, we discovered that m6A RNA modifiers play an important role in controlling KIRC and created a viable risk profile as a marker of prediction for KIRC clients.
Serological survey of Toxoplasma gondii infection in the one‐humped camels (Camelus dromedarius) in the south of Iran
Authors: Yektaseresht Azadeh , Ghane Mohsen , Atashbar Fatemeh , Aliabadi Jalal 
Published: August 2023

AbstractBackgroundToxoplasmosis, an important zoonotic disease, is caused by Toxoplasma gondii. Camels are one of several host species for T. gondii parasites and play an important role in the transmission of T. gondii to humans.ObjectivesThe present study aimed to describe the seroprevalence of T. gondii in dromedary camels (Camelus dromedarius) from three provinces (Fars, Bushehr and Hormozgan), southern Iran first for this host.MethodsA total of 180 serum samples were analysed for the presence of anti‐Toxoplasma IgG antibodies using the enzyme‐linked immune‐sorbent assay.ResultsOur results showed an overall seroprevalence of T. gondii in 15% of animals. Antibodies to T. gondii were found in sera of 27 of 180 dromedary camels from Fars, Bushehr and Hormozgan provinces, southern Iran. Age or the gender of the camel did not significantly affect the seroprevalence (p > 0.05). There was no significant association between herd‐level seroprevalence of T. gondii infection and abortion history, province location residence, history of animal keeping and history of contact with other animals (p > 0.05).ConclusionsThe results of this study showed the presence of T. gondii antibodies among camels in Southern Iran, which could be a public health concern. According to the prevalence of T. gondii infection in camel, the implementation of control measures to reduce infection in both definitive and intermediate hosts is needed.
Anti‐microbial resistance and aging—A design for evolution
Authors: Nepalia Amrita , Fernandes Sheryl Erica , Singh Harpreet , Rana Shweta , Saini Deepak Kumar 
Published: August 2023

AbstractThe emergence of resistance to anti‐infective agents poses a significant threat to successfully treating infections caused by bacteria. Bacteria acquire random mutations due to exposure to environmental stresses, which may increase their fitness to other selection pressures. Interestingly, for bacteria, the frequency of anti‐microbial resistance (AMR) seems to be increasing in tandem with the human lifespan. Based on evidence from previous literature, we speculate that increased levels of free radicals (Reactive Oxygen Species‐ROS and Reactive Nitrosative Species‐RNS), elevated inflammation, and the altered tissue microenvironment in aged individuals may drive pathogen mutagenesis. If these mutations result in the hyperactivation of efflux pumps or alteration in drug target binding sites, it could confer AMR, thus rendering antibiotic therapy ineffective while leading to the selection of novel drug‐resistant variants.This article is categorized under:
Immune System Diseases > Genetics/Genomics/Epigenetics
Infectious Diseases > Environmental Factors
Metabolic Diseases > Environmental Factors
Automorphisms and strongly invariant relations
Authors: Börner Ferdinand , Goldstern Martin , Shelah Saharon 
Published: August 2023

AbstractWe investigate characterizations of the Galois connection $${{\,\textrm{Aut}\,}}$$

Aut

-$${{\,\textrm{sInv}\,}}$$

sInv

between sets of finitary relations on a base set A and their automorphisms. In particular, for $$A=\omega _1$$

A
=

ω
1

, we construct a countable set R of relations that is closed under all invariant operations on relations and under arbitrary intersections, but is not closed under $${\textrm{sInv Aut}}$$

sInv Aut

. Our structure (A, R) has an $$\omega $$
ω
-categorical first order theory. A higher order definable well-order makes it rigid, but any reduct to a finite language is homogeneous.
Homogenised governing equations for pre-stressed poroelastic composites
Authors: Miller Laura , Di Stefano Salvatore , Grillo Alfio , Penta Raimondo 
Published: August 2023

AbstractWe propose the governing equations for a pre-stressed poroelastic composite material. The structure that we investigate possesses a porous elastic matrix with embedded elastic subphases with an incompressible Newtonian fluid flowing in the pores. Both the matrix and individual subphases are assumed to be linear elastic and pre-stressed. We are able to apply the asymptotic homogenisation technique by exploiting the length-scale separation that exists between the porescale and the overall size of the material (the macroscale). We derive the novel macroscale model which describes a poroelastic composite material where the elastic phases possess a pre-stress. We extend the current literature for poroelastic composites by addressing the role of the pre-stresses in the functional form of the new system of derived partial differential equations and its coefficients. The latter are computed by solving appropriate periodic cell differential problems which encode the specific contribution related to the pre-stresses. The model in the first instance is derived in the most general scenario and then specified for a variety of particular cases which are associated with different macroscale behaviour of materials.
Alcohol and morality: one alcoholic drink is enough to make people declare to harm others and behave impurely
Authors: Paruzel-Czachura Mariola , Pypno Katarzyna , Sorokowski Piotr 
Published: August 2023

AbstractWe aimed to understand if alcohol intoxication affects the willingness to violate moral foundations (care, fairness, authority, loyalty, and purity). We conducted a laboratory study (N = 387) with three randomized groups: alcohol intoxication, placebo, and control, measuring the sacralization of moral foundations via the Moral Foundations Sacredness Scale. The study showed intoxicated participants sacralized moral foundations of care and purity more often than participants from control and placebo groups. It means participants declared more willing to physically harm other people and animals and behave impurely, e.g., doing deviant sexual behaviors or selling their souls. No differences related to fairness, authority, and loyalty were found. Our study helps to understand the decision processes underlying immoral behaviors, including crimes. We showed that even one drink makes people change their judgments about what is right and wrong (in the cases of harmful and impure behaviors), and because this kind of judgment precedes immoral behaviors, our results may help explain why some people under the influence of alcohol break the rules by doing things which they would never do when sober.
Functional gene composition and metabolic potential of deep-sea coral-associated microbial communities
Authors: Pratte Zoe A. , Stewart Frank J. , Kellogg Christina A. 
Published: August 2023

AbstractOver the past decade, an abundance of 16S rRNA gene surveys have provided microbiologists with data regarding the prokaryotes present in a coral-associated microbial community. Functional gene studies that provide information regarding what those microbes might do are fewer, particularly for non-tropical corals. Using the GeoChip 5.0S microarray, we present a functional gene study of microbiomes from five species of cold-water corals collected from depths of 296–1567 m. These species included two octocorals, Acanthogorgia aspera and Acanthogorgia spissa, and three stony corals: Desmophyllum dianthus, Desmophyllum pertusum (formerly Lophelia pertusa), and Enallopsammia profunda. A total of 24,281 gene sequences (representing different microbial taxa) encoding for 383 functional gene families and representing 9 metabolic gene categories were identified. Gene categories included metabolism of carbon, nitrogen, phosphorus, and sulfur, as well as virulence, organic remediation, metal homeostasis, secondary metabolism and phylogeny. We found that microbiomes from Acanthogorgia spp. were the most functionally distinct but also least diverse compared against those from stony corals. Desmophyllum spp. microbiomes were more similar to each other than to E. profunda. Of 383 total gene families detected in this study, less than 20% were significantly different among these deep-water coral species. Similarly, out of 59 metabolic sub-categories for which we were able to make a direct comparison to microbiomes of tropical corals, only 7 were notably different: anaerobic ammonium oxidation (anammox), chitin degradation, and dimethylsulfoniopropionate (DMSP) degradation, all of which had higher representations in deep-water corals; and chromium homeostasis/resistance, copper homeostasis/resistance, antibiotic resistance, and methanogenesis, all of which had higher representation in tropical corals. This implies a broad-scale convergence of the microbial functional genes present within the coral holobiont, independent of coral species, depth, symbiont status, and morphology.
Separating Polynomial $$\chi $$-Boundedness from $$\chi $$-Boundedness
Authors: Briański Marcin , Davies James , Walczak Bartosz 
Published: August 2023

AbstractExtending the idea from the recent paper by Carbonero, Hompe, Moore, and Spirkl, for every function $$f:\mathbb {N}\rightarrow \mathbb {N}\cup \{\infty \}$$

f
:
N
→
N
∪
{
∞
}

with $$f(1)=1$$

f
(
1
)
=
1

and $$f(n)\geqslant \left( {\begin{array}{c}3n+1\\ 3\end{array}}\right) $$

f

(
n
)

⩾

3
n
+
1

3

, we construct a hereditary class of graphs $${\mathcal {G}}$$
G
such that the maximum chromatic number of a graph in $${\mathcal {G}}$$
G
with clique number n is equal to f(n) for every $$n\in \mathbb {N}$$

n
∈
N

. In particular, we prove that there exist hereditary classes of graphs that are $$\chi $$
χ
-bounded but not polynomially $$\chi $$
χ
-bounded.
Influence of gender and sexual hormones on outcomes after pituitary surgery: a systematic review and meta-analysis
Authors: Theiler Sven , Hegetschweiler Saskia , Staartjes Victor E. , Spinello Antonio , Brandi Giovanna , Regli Luca , Serra Carlo 
Published: August 2023

AbstractBackgroundAlthough there is an increasing body of evidence showing gender differences in various medical domains as well as presentation and biology of pituitary adenoma (PA), gender differences regarding outcome of patients who underwent transsphenoidal resection of PA are poorly understood. The aim of this study was to identify gender differences in PA surgery.MethodsThe PubMed/MEDLINE database was searched up to April 2023 to identify eligible articles. Quality appraisal and extraction were performed in duplicate.ResultsA total of 40 studies including 4989 patients were included in this systematic review and meta-analysis. Our analysis showed odds ratio of postoperative biochemical remission in males vs. females of 0.83 (95% CI 0.59–1.15,P = 0.26), odds ratio of gross total resection in male vs. female patients of 0.68 (95% CI 0.34–1.39,P = 0.30), odds ratio of postoperative diabetes insipidus in male vs. female patients of 0.40 (95% CI 0.26–0.64,P < 0.0001), and a mean difference of preoperative level of prolactin in male vs. female patients of 11.62 (95% CI − 119.04–142.27,P = 0.86).ConclusionsThere was a significantly higher rate of postoperative DI in female patients after endoscopic or microscopic transsphenoidal PA surgery, and although there was some data in isolated studies suggesting influence of gender on postoperative biochemical remission, rate of GTR, and preoperative prolactin levels, these findings could not be confirmed in this meta-analysis and demonstrated no statistically significant effect. Further research is needed and future studies concerning PA surgery should report their data by gender or sexual hormones and ideally further assess their impact on PA surgery.