bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH APLIKASI EDUKASI E-BOOK DALAM PENCEGAHAN DIABETES MELLITUS TYPE II (DMT II) PADA REMAJA DI ERA PANDEMI COVID 19
Authors: Lundy Fiashriel , Suryani Pudji , Halis Farida 
Published: June 2023

Latar Belakang: Pandemi COVID-19 menjadi tantangan dalam pendidikan kesehatan khususnya dalam pencegahan Diabetes Melitus Tipe2. E-Book merupakan salah satu metode alternatif yang dapat digunakan oleh tenaga kesehatan untuk menginformasikan atau mengedukasi klien. Penelitian ini bertujuan untuk mengetahui pengaruh aplikasi e-book terhadap pencegahan Diabetes Melitus tipe II di era pandemi covid 19.
Subjek dan Metode: Penelitian ini menggunakan desain quasy eksperiment pada remaja di mojolangu kota malang. Sampel peneltian ini sebanyak 60 responden, dibagi menjadi 2 kelompok dengan menggunakan tehnik purposive sampling. Variabel Independent pada penelitian ini adalah Aplikasi Edukasi E-Book pada Remaja dan Variabel Dependentnya adalah Upaya Pencegahan Penyakit Diabetes Mellitus Tipe II melalui Monitoring Kadar Gula darah dan IMT.Pengumpulan data dilakukan dengan kuesioner. Selanjutnya Data dianalisis dengan Uji Wilcoxon.
Hasil: Dari Hasil uji Wilcoxon diperoleh p-value sebesar <0,001 sehingga artinya terdapat perubahan signifikan antara sebelum dan sesudah perlakuan terhadap pengetahuan dengan pemberian edukasi dengan menggunakan aplikasi e-book. Sedangkan pada kelompok kontrol didapatkan hasil adanya peningkatan pengetahuan tetapi tidak diikuti perubahan IMT dan kadar gula darah. Dari Hasil Uji Wilcoxon menunjukkan pengaruh Edukasi menggunakan booklet terhadap pengetahuan, indeks massa tubuh dan kadar gula darah, antara sebelum dan sesudah perlakuan didapatkan hasil p-value sebesar 0,317 pada IMT dan 0.362 terhadap kadar gula darah dengan kriteria apabila p-value < 0,05 maka dinyatakan terdapat perubahan signifikan antara sebelum dan sesudah perlakuan, sedangkan apabila p-value > 0,05 maka dinyatakan tidak terdapat perubahan signifikan antara sebelum dan sesudah perlakuan.
Kesimpulan: Model Edukasi menggunakan Aplikasi E-Book dapat digunakan sebagai alternatif model Edukasi pada remaja dalam meningkatkan upaya pencegahan Diabetes Mellitus Tipe II
O perfil da tipicidade no direito tributário brasileiro: tipicidade aberta ou fechada?
Authors: Medeiros João Maria Pegado 
Published: June 2023

This article aims to answer, albeit provisionally, whether the Brazilian Tax Law supports a principle that demands an exhaustive list of all elements to calculate a tax in a law voted by the parliament or if some elements could be fixed by the Executive Branch or administrative agencies. In Brazil and Portugal, this principle is called typicality and for some authors, it demands the first one option quoted. To try answer the question, the article departs from the conception bequeathed by Alberto Xavier, Portuguese author who greatly influenced Brazilians authors and court decisions. The hypothesis is that, despite the terminological impropriety, resulting from the use of the terms type and typicality, the requirement is not for defined types, but the principle demands that the elements to calculate the tax must be in a law voted by the parliament with by use of determined or determinable concepts. Keywords: Tax law, Taxability. JEL: Tax Law K34
ANALISIS KEBUTUHAN LKPD FISIKA BERBASIS POE (PREDICT, OBSERVE, EXPLAIN) DI SMP SABILILLAH KABUPATEN MUSI RAWAS
Authors: Arini Wahyu , Sulistiyono Sulistiyono 
Published: June 2023

Penelitian ini dilaksanakan untuk mengembangkan bahan ajar berupa lembar kerja peserta didik berbasis POE, sehingga diperlukan studi pendahuluan yang terdiri atas studi literatur dan studi lapangan. Jenis penelitian yang dilakukan adalah penelitian deskriptif kualitatif. Instrumen pengumpulan data penelitian ini berupa lembar wawancara analisis kebutuhan guru, dan angket analisis kebutuhan peserta didik. Media pembelajaran yang akan dikembangkan berupa LKPD Fisika berbasis POE. Analisis kebutuhan dilakukan untuk mengetahui bahan ajar digunakan guru, kendala saat pembelajaran berlangsung, dan bahan ajar diperlukan peserta didik. Hasil analisis kebutuhan 32 peserta didik kelas VIII SMP Sabililah diperoleh 84,4% memiliki buku pegangan untuk belajar fisika akan tetapi, 97,7% peserta didik materi getaran dan gelombang di dalam buku pegangan sulit dipahami. Sehingga menurut 87,5% peserta didik buku pegangan yang digunakan belum mencukupi sebagai sumber belajar dan 95,5% peserta didik membutuhkan bahan ajar lain untuk menunjang kegiatan belajar serta 93,7% peserta didik membutuhkan bahan ajar lain yang dapat meningkatkan keterampilan berpikir tingkat tinggi. Hasil tersebut menunjukkan perlunya dikembangkan bahan ajar berupa LKPD berbasis POE materi getaran dan gelombang.
Searching for an ‘Authentic Encounter’
Authors: Lengauer Dayana 
Published: June 2023

Abstract
By attending to the conceptualisations of interfaith student and youth groups in Bandung, Indonesia, in response to state ideologies and regulatory policies, this article examines new approaches to the concept of pluralism – approaches that recognise the affective economies of how people construe and deal with difference. Conceptualisations of ‘authentic encounter’ not only pose a direct critique to the dividing effects of the legal codification and categorisation of difference – a critique that anthropologists working in societies characterised by ethnic and religious diversity voiced alongside feminist thinkers – but also reveal great potential for theoretical reflections from below. By drawing on contemporary anthropological work on pluralism in Southeast Asia and leaning on the anthropological literature on affect, this article shows how conceptualisations of ‘authentic encounter’, which circulate among groups of predominantly young activists, situate feelings and emotional states directly into ideas of how diversity should be dealt with. By doing so, they not only challenge the limits of pluralism as a politico-legal category but also espouse a concept of pluralism that is essentially embedded in the emotional life and social activities of those living with difference.

Résumé
Cet article propose une nouvelle approche du concept de pluralisme. Il propose une enquête sur les conceptions des groupes étudiants et de jeunesse interreligieux en réponse aux idéologies d’État et aux politiques de contrôle à Bandung en Indonésie. Je suis intéressons particulièrement aux « économies affectives » qui permettent aux personnes d'interpréter et de mieux comprendre la différence. Les conceptualisations de la rencontre authentique ne posent pas seulement une critique directe aux effets de démarcation liés à la codification juridique et au classement de la différence – les anthropologues qui travaillent dans des sociétés caractérisées par la diversité religieuse et ethnique, ainsi que les chercheurs féministes, ont déjà exprimé cette critique. Ces mêmes conceptualisations possèdent également un potentiel pour la réflexion théorique, notamment sur le pluralisme en Asie du sud-est et pour l'anthropologie des affects. Je montre comment les conceptualisations de la rencontre authentique, qui circulent parmi des groupes activistes majoritairement jeunes, transposent des sentiments et des états émotionnels en idées pour interpréter la diversité. En agissant ainsi, ces groupes contestent les limites de pluralisme en tant que catégorie politique et légale. Ils expriment aussi un concept de pluralisme ancré dans la vie émotionnelle et les activités sociales de ceux qui vivent avec la différence.
Metabolism changes during direct revascularization in moyamoya disease: illustrative case
Authors: Arikan Fuat , Chocron Ivette , Calvo-Rubio Helena , Santos Carlos , Gándara Dario 
Published: June 2023

BACKGROUND
Cerebral revascularization is recommended for patients with moyamoya disease (MMD) with reduced cerebral perfusion reserve and recurrent or progressive ischemic events. The standard surgical treatment for these patients is a low-flow bypass with or without indirect revascularization. The use of intraoperative monitoring of the metabolic profile using analytes such as glucose, lactate, pyruvate, and glycerol has not yet been described during cerebral artery bypass surgery for MMD-induced chronic cerebral ischemia. The authors aimed to describe an illustrative case using intraoperative microdialysis and brain tissue oxygen partial pressure (PbtO2) probes in a patient with MMD during direct revascularization.

OBSERVATIONS
The patient’s severe tissue hypoxia situation was confirmed by a PbtO2:partial pressure of oxygen (PaO2) ratio below 0.1 and anaerobic metabolism by a lactate:pyruvate ratio greater than 40. Following bypass, a rapid and sustained increase in PbtO2 up to normal values (PbtO2:PaO2 ratio between 0.1 and 0.35) and the normalization of cerebral energetic metabolism with a lactate/pyruvate ratio less than 20 was observed.

LESSONS
The results show a quick improvement of regional cerebral hemodynamics due to the direct anastomosis procedure, reducing the incidence of subsequent ischemic stroke in pediatric and adult patients immediately.
Delayed myelopathy after remote C1–2 sublaminar wire fixation: illustrative case
Authors: Miller Aaron , Paul David A. , Romiyo Prasanth , Stone Jonathan J. 
Published: June 2023

BACKGROUND
Atlantoaxial sublaminar wiring complications, both early and delayed, have been documented. However, delayed neurological compromise 27 years after successful fusion is a rare but possible occurrence.

OBSERVATIONS
A 76-year-old male, who had undergone C1–2 sublaminar wire fusion for atlantoaxial instability in 1995, presented with symptoms of progressive right arm weakness, falls, and incontinence of bowel and bladder over a 1-week period. Initial imaging workup revealed bowing of the C1–2 sublaminar wires resulting in cervical spinal cord compression and T2-weighted signal changes. A C1–2 laminectomy was performed to remove the wires and decompress the spinal cord with improvement in the patient’s neurological status.

LESSONS
This rare case highlights the potential for delayed cervical myelopathy and cord compression from sublaminar wires, even after a successful fusion. In patients with a history of sublaminar wiring who experience new neurological deficits, it is essential to evaluate the hardware for migration.
Cronobacter brain abscess and refractory epilepsy in a newborn: role of epilepsy surgery. Illustrative case
Authors: Yang Meredith , Tsiang John , LoPresti Melissa A. , Lam Sandi 
Published: June 2023

BACKGROUND
Neonatal meningitis due to Cronobacter is associated with powdered infant formula. Prompt recognition of this rare but aggressive infection is critical.

OBSERVATIONS
The authors report a unique case of neonatal Cronobacter meningoencephalitis complicated by brain abscess and status epilepticus, requiring surgical intervention in a preterm 4-week-old male and related to contaminated powdered infant formula. They discuss the medical and surgical management in this patient, as well as the role of epilepsy surgery in acute drug-resistant epilepsy. This is paired with a literature review examining Cronobacter infections in infants to provide a summative review of the existing literature.

LESSONS
Cronobacter contamination in powdered infant formula and breast pumps is rare but can cause life-threatening infections. When evaluating patients with Cronobacter central nervous system infections, serial neuroimaging, infection control, and prompt surgical management are essential. Future studies are needed regarding the role of epilepsy surgery in the acute infectious period.
Multifocal primary central nervous system angiosarcoma: illustrative case
Authors: Hirai Satoshi , Tao Yoshifumi , Nishimura Hirotake , Nakazaki Kiyoshi , Uno Masaaki 
Published: June 2023

BACKGROUND
Angiosarcoma is a malignant mesenchymal tumor derived from vascular endothelial cells in which a primary intracranial origin is extremely rare. Most previous reports of primary central nervous system (CNS) angiosarcoma have been solitary cases.

OBSERVATIONS
The authors report a case of primary CNS angiosarcoma that caused the development of multiple disseminated cerebral hemorrhagic lesions within a short period of time. This rapid progression of symptoms resulted in the death of the patient. During surgery, several nodules suggestive of a tumor were removed from just below the surface of the brain, mixed into the hematoma. A pathological examination revealed atypical cells mimicking blood vessels in the subarachnoid space that were positive for specific vascular endothelial markers.

LESSONS
In this case, multifocal angiosarcoma occurred on the brain surface and ventricles, suggesting cerebrospinal fluid dissemination. If multiple cerebral hemorrhages are found on the brain surface, multifocal angiosarcoma should also be considered.
Direct withdrawal of a retained foreign body bisecting the thoracic spinal canal in a neurologically intact pediatric patient: illustrative case
Authors: Peters David R. , VanHorn Trent , Karimian Brandon , Pruden Benjamin , Wait Scott D. , Daniel Roy T. , Tuleasca Constantin 
Published: June 2023

BACKGROUND
Nonmissile penetrating spinal cord injury (NMPSCI) with a retained foreign body (RFB) is rare and usually results in permanent neurological deficits. In extremely rare cases, patients can present without significant neurological deficits despite an RFB that traverses the spinal canal. Given the rarity of these cases, a consensus has not yet been reached on optimal management. In a patient with an RFB and a neurologically normal clinical examination, the risk of open surgical exploration may outweigh the benefit and direct withdrawal may be a better option.

OBSERVATIONS
A 10-year-old female suffered an NMPSCI to the thoracic spine with an RFB that bisected the spinal canal but remained neurologically intact. Direct withdrawal of the RFB was chosen instead of open surgical exploration, leading to an excellent clinical outcome. The literature was reviewed to find other examples of thoracic NMPSCI with RFB and neurologically normal examinations. Management strategies were compared.

LESSONS
For NMPSCI with RFB and without significant neurological deficits, direct withdrawal is a viable and possibly the best treatment option. The use of fast-acting anesthesia without intubation minimizes patient manipulation, speeds up recovery, and allows early assessment of neurological status after removal.
Rathke’s cleft cyst presenting with recurrent aseptic meningitis and inflammatory apoplexy: illustrative case
Authors: Murayi Roger , Trivedi Megh M. , Almeida Joao Paulo , Yeaney Gabrielle , Isada Carlos , Kshettry Varun R. 
Published: June 2023

BACKGROUND
Rathke’s cleft cyst (RCC) is a benign sellar/suprasellar lesion often discovered incidentally. Rarely, symptomatic cases can present with headache and may exhibit concomitant aseptic meningitis or apoplexy. The authors describe a patient with an RCC presenting with recurring episodes of aseptic meningitis and ultimately inflammatory-type apoplexy.

OBSERVATIONS
A 30-year-old female presented with three episodes of intractable headaches over 2 months. Each episode’s clinical picture was consistent with meningitis though cerebrospinal fluid cultures, and viral tests remained negative. Imaging demonstrated a sellar lesion, initially thought to be coincidental. On the third presentation, there was rapid interval growth of the lesion, adjacent cerebritis, and new endocrinopathy. Resection was then performed via an endoscopic endonasal approach. Pathology showed an RCC with acute and chronic inflammation and no evidence of hemorrhage. Cultures were negative for organisms. The patient received several weeks of antibiotic treatment with the resolution of all symptoms and no recurrence.

LESSONS
Recurrent aseptic meningitis with apoplexy-like symptoms is a rare presentation of RCC. The authors propose the term inflammatory apoplexy to describe such a presentation without evidence of abscess, necrosis, or hemorrhage. The mechanism is unclear although may be due to intermittent microleakage of cyst contents into the subarachnoid space.
Determining the effect of seaweed intake on the microbiota: a systematic review
Authors: Hagan Miriam , Fungwe Thomas 
Published: June 2023

The human gut microbiota is dominated by bacteria, and the host dietary intake is one factor that can modulate the diversity of the gut microbiota to health or diseases. According to the FAO, there is an annual steady decline in agricultural practices of over one percent. There has been an anticipation that algae production will be increased to supplement the use of vegetables from terrestrial land. Seaweed is a sustainable crop that offers a rich source of bioactive compounds, yet its potential is not fully exploited. Seaweeds) has been part of the staple diets of East Asian populations for a long time, and their bioactive compounds have the potential to be functional foods. As such, it has become pertinent to explore how seaweed can modulate gut microbial composition and function to improve host health. The purpose of the study is to conduct an extensive literature review to ascertain what is known about the effects of seaweed on the microbiota. A systematic search was conducted using relevant databases to find studies looking at the effects of green seaweed on the microbiota. From all 8,951 search results, 7 publications were included in this systematic review. The result showed that seaweed has a prebiotic effect in vitro digestive systems and a significant increase in SCFA production. Studies indicated that oligosaccharides and polysaccharides gotten from seaweed can regulate intestinal metabolism and could manage inflammatory bowel disease. The results of this review showed that consumption of seaweed is beneficial to the host and the gut microbiota.Keywords: Seaweed, algae, marine algae, flora, microbiota
The anti-tumor activity and critical active compounds of polyphenols from Chinese dwarf cherry (Cerasus humilis)
Authors: Zhang Yushi , Gu Jinrui , Wang Yu , Zhao Zihan , Wang Zhanjun , Li Weidong 
Published: June 2023

BACKGROUND: Cerasus humilis (Bge.) Sok. fruit ( C. humilis) is rich in polyphenols and has a potential anti-tumor effect. However, its anti-tumor functional compositions and mechanism remain unclear. OBJECTIVE: This study aims to investigate the antitumor activity and chemical composition of polyphenols from C. humilis, and to identify the critical antitumor substances and potential mechanisms. METHODS: Polyphenols of 14 germplasms were extracted and purified; the inhibitory effects of C. humilis polyphenols on the proliferation of liver cancer HepG2 cells, colon cancer HCT116 cells, and gastric cancer BGC823 cells were evaluated by MTT assay; polyphenol compounds were identified by ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry; partial least squares were utilized to build chemometrics models for selecting anti-tumor compounds; the key targets and pathways of antitumor effects of C. humilis were predicted by network pharmacology. RESULTS: The total polyphenol content ranged from 275.9 to 598.2 mg/100 g fresh weight, with an average of 381.2 mg/100 g FW; C. humilis polyphenols has potent inhibitory effects on liver, colon, and gastric cancer cells; twenty-three polyphenols were identified; a total of 12, 17, and 18 components were anti-liver cancer, anti-colon cancer, and anti-gastric cancer active polyphenols, respectively; TP53, MAPK3, MAPK1, RELA, AKT1, PIK3R1 and other 16 genes are the key anti-tumor targets; pathway in cancer, lipid and atherosclerosis, colorectal cancer, microRNAs in caner, HIF-1 signaling pathway and other pathways are the key pathways for anti-tumor effects of C. humilis. CONCLUSIONS: C. humilis polyphenols can be developed as a functional natural product to intervene in liver, stomach, and colon cancers.
АНАЛІЗ ОБЛАДНАННЯ ДЛЯ ГАСІННЯ ЕЛЕКТРОМОБІЛІВ ТА РОЗРОБКА РЕКОМЕНДАЦІЙ З ЇХ ГАСІННЯ
Authors: Parkhomenko V.-P. O. , Lazarenko O. V. , Sukach R. Yu. 
Published: June 2023

Вступ. Завдяки науково-технічному прогресу широкого використання набули транспортні засоби, що працюють на альтернативних джерелах енергії. Використання таких транспортних засобів є значно дешевшим, для користувача порівняно із транспортними засобами, що працюють на двигунах внутрішнього згорання. Одним із таких перспективних транспортних засобів є електричні.Мета та задачі дослідження. Метою роботи є висвітлення закордонного досвіду гасіння електричних транспортних засобів та розроблення рекомендації для особового складу пожежно-рятувальних підрозділів щодо їхніх дій під час гасіння загорань електромобілів.Для досягнення поставленої мети необхідно: провести аналіз обладнання з гасіння цього типу транспортних засобів, розробити рекомендації пожежно-рятувальним підрозділам щодо дій за призначенням на подібних транспортних засобах та схеми розташування сил та засобів при проведенні їх гасіння.Методи. Для досягнення поставленої мети та задач дослідження було використано теоретичні методи дослідження, що включали аналіз дій особового складу пожежно-рятувальних підрозділів з гасіння електромобілів та узагальнення отриманих результатів дослідження з подальшою їх систематизацією для досягнення поставленої мети дослідження.Результати. За результатами огляду літературних джерел було здійснено аналіз обладнання для гасіння електромобілів. З метою забезпечення безпечних умов праці та швидкого реагування особового складу пожежно-рятувальних підрозділів на ліквідації імовірних НС було розроблено рекомендації щодо дій пожежно-рятувальних підрозділів на місці події під час гасіння електричних транспортних засобів та схеми розташування сил та засобів залежно від місця виникнення пожежі.Висновки. Представлені результати дають підґрунтя для розроблення подальшої єдиної нормативної бази для України та країн ЄС, загальноприйнятих методичних рекомендацій щодо дій особового складу пожежно-рятувальних підрозділів з гасіння літій-іонних батарей електромобілів, подальшого дослідження ефективності представлених способів гасіння та розробки нових.