bluuebunny/crossref_metadata_2025_split huggingface dataset:
Labor Secretary Frances Perkins Reorganizes Her Department’s Immigration Enforcement Functions, 1933–1940: “Going against the Grain”
Authors: HERNANDEZ NEIL V. 
Published: December 2022

AbstractLabor Secretary Frances Perkins championed liberal immigration policies between 1933 and 1940. Some efforts were successful, but most were not due to political, economic, and social constraints on immigration policy making, especially in Congress. Yet, she reorganized the enforcement functions of her department when she created the Immigration and Naturalization Service. Narratives abound about the period, though few delve into this reorganization. In this article, I share an analytical framework that I developed, “policy innovation through bureaucratic reorganization,” to explain how Perkins temporarily eased the debarments, as well as deportations, of newcomers by adjusting agency resources, including staffing, budget, and infrastructure. I describe how she responded to pressures from immigration restrictionists by tightening these functions. My narrative adds to the literature on immigration policy history, which has not fully appreciated the role of bureaucratic reorganization. This research bolsters the perspective in political control theory that bureaucratic structure merits as much attention as does legislation as a tool for control.
Flecainide administration in children: dosage, drug levels, and clinical effect
Authors: Thomas Shôn A. L. , Ferguson Richard , Wilson Dirk G. 
Published: December 2022

AbstractTherapeutic drug monitoring of flecainide in children using plasma concentration measurements is undertaken by some clinicians. There is very little published evidence surrounding factors which influence plasma flecainide concentration, particularly in paediatric populations. We undertook a retrospective study of 45 children receiving flecainide to identify factors that influence its plasma concentration. Patients receiving a dose of 6 mg/kg/day had a higher mean plasma flecainide concentration than those receiving lower doses. Younger age and lighter weight were also associated with higher plasma flecainide concentrations. Children aged younger than 1 year receiving flecainide three times a day had a higher mean plasma flecainide concentration than older children who received flecainide twice a day. All supratherapeutic levels occurred in children aged less than 1 year who were receiving flecainide three times a day. Supratherapeutic levels were more common in those receiving 6 mg/kg/day while subtherapeutic levels were more common in those receiving 2 mg/kg/day. A supratherapeutic level did not correlate with adverse effects or clinical toxicity. Our results would suggest the need for a change of practice from prescribing flecainide at a frequency of three times a day in children aged younger than 1 year to twice a day in line with other ages.
SEN: A subword-based ensemble network for Chinese historical entity extraction
Authors: Yan Chengxi , Wang Ruojia , Fang Xiaoke 
Published: December 2022

AbstractUnderstanding various historical entity information (e.g., persons, locations, and time) plays a very important role in reasoning about the developments of historical events. With the increasing concern about the fields of digital humanities and natural language processing, named entity recognition (NER) provides a feasible solution for automatically extracting these entities from historical texts, especially in Chinese historical research. However, previous approaches are domain-specific, ineffective with relatively low accuracy, and non-interpretable, which hinders the development of NER in Chinese history. In this paper, we propose a new hybrid deep learning model called “subword-based ensemble network” (SEN), by incorporating subword information and a novel attention fusion mechanism. The experiments on a massive self-built Chinese historical corpus CMAG show that SEN has achieved the best with 93.87% for F1-micro and 89.70% for F1-macro, compared with other advanced models. Further investigation reveals that SEN has a strong generalization ability of NER on Chinese historical texts, which is not only relatively insensitive to the categories with fewer annotation labels (e.g., OFI) but can also accurately capture diverse local and global semantic relations. Our research demonstrates the effectiveness of the integration of subword information and attention fusion, which provides an inspiring solution for the practical use of entity extraction in the Chinese historical domain.
Boundary Currents at the Northern Edge of the Chukchi Sea at 166°W
Authors: Li Min , Pickart Robert S. , Lin Peigen , Woodgate Rebecca A. , Wang Guiyuan , Xie Lingling 
Published: December 2022

AbstractData from two moorings deployed at 166°W on the northern Chukchi shelf and slope from summer 2002 to fall 2004, as part of the Western Arctic Shelf‐Basin Interactions program, are analyzed to investigate the characteristics and variability of the flow in this region. The depth‐mean velocity at the outer‐shelf mooring is northeastward and bottom‐intensified, while that at the upper‐slope mooring is northwestward and surface‐intensified. This, together with results from a high resolution ocean and sea ice reanalysis, indicates that the outer‐shelf mooring sampled the seaward edge of the Chukchi Shelfbreak Jet, while the upper‐slope mooring sampled the shoreward edge of the Chukchi Slope Current. The coupled variability in velocity at both sites is related to the wind stress curl over the Chukchi Sea shelf, likely via Ekman dynamics and geostrophic set up, analogous to the dynamics of both currents closer to Barrow Canyon near 157°W. Hydrographic signals are analyzed to elucidate the origin of the water masses present at this location. It is argued that the annual appearance of Pacific‐origin warm water at the outer‐shelf (upper‐slope) mooring in late‐fall and winter originates from Herald (Barrow) Canyon some months earlier. Our results constitute the first robust evidence that the westward‐flowing Chukchi Slope Current persists this far west of Barrow Canyon.
Geomorphological Map of the Soi Crater Region on Titan
Authors: Schoenfeld A. M. , Solomonidou A. , Malaska M. J. , Lopes R. M. C. , Birch S. P. D. , Le Mouélic S. , Florence M. , Verlander T. , Wall S. D. , Elachi C. 
Published: December 2022

AbstractWe mapped the Soi crater region at 1:800,000 scale and produced a geomorphological map using methodology presented by Malaska, Lopes, Williams, et al. (2016), https://doi.org/10.1016/j.icarus.2016.02.021 and Schoenfeld et al. (2021), https://doi.org/10.1016/j.icarus.2021.114516. This region spans longitude 110° to 180°W and latitude 0° to 60°N and is representative of the transition between the equatorial, mid‐latitude, and high‐latitude northern regions of Titan. We used Cassini Synthetic Aperture Radar (SAR) as our primary mapping data set. For areas where SAR was not available, we used lower resolution data from the Imaging Science Subsystem, the Visible and Infrared Mapping Spectrometer, radiometry, and high‐altitude SAR for complete mapping coverage of the region. We identified 22 geomorphological units, 3 of which have been discussed in existing literature but have not yet been incorporated into our mapping investigations. These include sharp‐edged depressions (bse), ramparts (brh), and bright gradational plains (pgh). All six major terrain classes are represented in this region: Craters, Labyrinth, Hummocky/mountainous, Plains, Dunes, and Basin and Lakes. We find that plains dominate the surface of the Soi crater region, comprising ∼73% of the mapped area, followed by dunes (∼14%), mountains/hummocky terrains (∼12%), basin and lakes (∼0.7%), labyrinth terrains (∼0.5%), and crater terrains (∼0.4%). We also observe empty lakes as far south as 40°N. The Soi crater region largely has the same collection and proportion of geomorphological units to other mapped regions on Titan. These results further support the hypothesis that surface processes are, broadly speaking, the same across Titan's middle and equatorial latitudes, with the exception of Xanadu.
Salt Marsh Response to Inlet Switch‐Induced Increases in Tidal Inundation
Authors: Yellen Brian , Woodruff Jonathan D. , Baranes Hannah E. , Engelhart Simon E. , Geyer W. Rockwell , Randall Noa , Griswold Frances R. 
Published: December 2022

AbstractThere is widespread concern that rapidly rising sea levels may drown salt marshes by exceeding the rate at which these important ecosystems can build elevation. A significant fraction of marshes reside within backbarrier estuaries, yet little attention has been paid to how changes in inlet geometry influences estuarine tides and marshes. In 1898, a coastal storm eroded a new inlet through the barrier beach that fronts the North‐South Rivers Estuary in Massachusetts, USA. The new inlet shortened the North River by 5.6 km and lengthened the South River channel by the same amount. Modern measurements of tidal attenuation suggest that channel shortening abruptly increased mean high tide along the North River by at least 30 cm. Foraminifera communities within North River marsh sediments indicated an environmental change from infrequent to frequent inundation at the time of the 1898 switch in inlet location, which supports this hypothesis. Increased mineral sediment deposition after the inlet switch played a dominant role in allowing marshes along the North River channel to adjust to greater inundation. Following the inlet switch, sediment accreted in North River marshes at 2–5 times the rate of sea level rise (SLR). The North River channel widened by an average of 18% relative to pre‐1898 conditions to accommodate the increased tidal prism. The role of mineral sediment accretion in making this marsh resilient to an abrupt increase in inundation depth highlights the importance of maintaining adequate sediment supplies in coastal regions as SLR accelerates.
Drivers of Variation in Winter and Spring Groundwater Recharge: Impacts of Midwinter Melt Events and Subsequent Freezeback
Authors: Hyman‐Rabeler Katrina A. , Loheide Steven P. 
Published: December 2022

AbstractIn areas with seasonal snowfall, the spring snowmelt often accounts for a large percentage of annual groundwater recharge. As climates warm, midwinter snowmelts are becoming more common. Although midwinter melt events can cause discrete recharge events, they can also increase soil water content and leave the ground exposed to subsequent cold periods. Without the insulating effects of snow, frozen ground can develop, which can prevent infiltration during subsequent melt events, reducing recharge, and increasing overland flow. We investigated relationships between winter precipitation, the soil thermal regime, and recharge to determine the factors that contribute to variation in winter‐spring recharge. We found that statistically significant predictors of variation in winter‐spring recharge, controlling for precipitation, were amount and cover of snow, evapotranspiration/sublimation, air temperature, and number of freezeback events occurring between two melt events. We observed that midwinter snowmelt followed by freezeback and subsequent melt events correlated with lower than expected recharge. We quantify the occurrence of this sequence of events (snowmelt followed by freezeback and another melt) and demonstrate its effect in reducing recharge in a multiyear, multilocation statistical analysis. This finding indicates that frozen ground plays a role the partitioning of precipitation between recharge and runoff, but the effect is sensitive to the magnitude and temporal sequence of precipitation events and temperature fluctuations. Understanding the complex relationships between snow, midwinter melt and freezeback events, frozen ground, and recharge is critical for predicting how climate change will affect groundwater resources in the future.
Entanglement-assisted quantum communication with simple measurements
Authors: Piveteau Amélie , Pauwels Jef , Håkansson Emil , Muhammad Sadiq , Bourennane Mohamed , Tavakoli Armin 
Published: December 2022

AbstractDense coding is the seminal example of how entanglement can boost qubit communication, from sending one bit to sending two bits. This is made possible by projecting separate particles onto a maximally entangled basis. We investigate more general communication tasks, in both theory and experiment, and show that simpler measurements enable strong and sometimes even optimal entanglement-assisted qubit communication protocols. Using only partial Bell state analysers for two qubits, we demonstrate quantum correlations that cannot be simulated with two bits of classical communication. Then, we show that there exists an established and operationally meaningful task for which product measurements are sufficient for the strongest possible quantum predictions based on a maximally entangled two-qubit state. Our results reveal that there are scenarios in which the power of entanglement in enhancing quantum communication can be harvested in simple and scalable optical experiments.
Greenstone burial–exhumation cycles at the late Archean transition to plate tectonics
Authors: Ivan Zibra , Anthony I S Kemp , R Hugh Smithies , Daniela Rubatto , Fawna Korhonen , Johannes Hammerli , Tim E Johnson , Klaus Gessner , Roberto F Weinberg , Jeff D Vervoort , Laure Martin , Sandra S Romano 
Published: December 2022

AbstractConverging lines of evidence suggest that, during the late Archean, Earth completed its transition from a stagnant-lid to a plate tectonics regime, although how and when this transition occurred is debated. The geological record indicates that some form of subduction, a key component of plate tectonics—has operated since the Mesoarchean, even though the tectonic style and timescales of burial and exhumation cycles within ancient convergent margins are poorly constrained. Here, we present a Neoarchean pressure–temperature–time (P–T–t) path from supracrustal rocks of the transpressional Yilgarn orogen (Western Australia), which documents how sea-floor-altered rocks underwent deep burial then exhumation during shortening that was unrelated to the episode of burial. Archean subduction, even if generally short-lived, was capable of producing eclogites along converging lithosphere boundaries, although exhumation processes in those environments were likely less efficient than today, such that return of high-pressure rocks to the surface was rare.
Switchable Na+ and K+ selectivity in an amino acid functionalized 2D covalent organic framework membrane
Authors: Cao Li , Chen I-Chun , Li Zhen , Liu Xiaowei , Mubashir Muhammad , Nuaimi Reham Al , Lai Zhiping 
Published: December 2022

AbstractBiological cell membranes can efficiently switch Na+/K+ selectivity in response to external stimuli, but achieving analogous functions in a single artificial membrane is challenging. Here, we report highly crystalline covalent organic framework (COF) membranes with well-defined nanochannels and coordinative sites (i. e., amino acid) that act as ion-selective switches to manipulate Na+ and K+ transport. The ion selectivity of the COF membrane is dynamic and can be switched between K+-selective and Na+-selective in a single membrane by applying a pH stimulus. The experimental results combined with molecular dynamics simulations reveal that the switchable Na+/K+ selectivity originates from the differentiated coordination interactions between ions and amino acids. Benefiting from the switchable Na+/K+ selectivity, we further demonstrate the membrane potential switches by varying electrolyte pH, miming the membrane polarity reversal during neural signal transduction in vivo, suggesting the great potential of these membranes for in vitro biomimetic applications.
Slight compositional variation-induced structural disorder-to-order transition enables fast Na+ storage in layered transition metal oxides
Authors: Shi Yuansheng , Jiang Pengfeng , Wang Shicheng , Chen Weixin , Wei Bin , Lu Xueyi , Qian Guoyu , Kan Wang Hay , Chen Huaican , Yin Wen , Sun Yang , Lu Xia 
Published: December 2022

AbstractThe omnipresent Na+/vacancy orderings change substantially with the composition that inevitably actuate the ionic diffusion in rechargeable batteries. Therefore, it may hold the key to the electrode design with high rate capability. Herein, the influence of Na+/vacancy ordering on Na+ mobility is demonstrated firstly through a comparative investigation in P2-Na2/3Ni1/3Mn2/3O2 and P2-Na2/3Ni0.3Mn0.7O2. The large zigzag Na+/vacancy intralayer ordering is found to accelerate Na+ migration in P2-type Na2/3Ni1/3Mn2/3O2. By theoretical simulations, it is revealed that the Na+ ordering enables the P2-type Na2/3Ni1/3Mn2/3O2 with higher diffusivities and lower activation energies of 200 meV with respect to the P3 one. The quantifying diffusional analysis further prove that the higher probability of the concerted Na+ ionic diffusion occurs in P2-type Na2/3Ni1/3Mn2/3O2 due to the appropriate ratio of high energy ordered Na ions (Naf) occupation. As a result, the interplay between the Na+/vacancy ordering and Na+ kinetic is well understood in P2-type layered cathodes.
The electric field cavity array effect of 2D nano-sieves
Authors: Xu Fan , Li Yuke , Zou Qing , He Yu Shuang , Shen Zijia , Li Chen , Zhang Huijuan , Wang Feipeng , Li Jian , Wang Yu 
Published: December 2022

AbstractFor the upsurge of high breakdown strength ($${{{{{{\rm{E}}}}}}}_{{{{{{\rm{b}}}}}}}$$

E

b

), efficiency ($${{{{{\rm{\eta }}}}}}$$
η
), and discharge energy density ($${{{{{{\rm{U}}}}}}}_{{{{{{\rm{e}}}}}}}$$

U

e

) of next-generation dielectrics, nanocomposites are the most promising candidates. However, the skillful regulation and application of nano-dielectrics have not been realized so far, because the mechanism of enhanced properties is still not explicitly apprehended. Here, we show that the electric field cavity array in the outer interface of nanosieve-substrate could modulate the potential distribution array and promote the flow of free charges to the hole, which works together with the intrinsic defect traps of active Co3O4 surface to trap and absorb high-energy carriers. The electric field and potential array could be regulated by the size and distribution of mesoporous in 2-dimensional nano-sieves. The poly(vinylidene fluoride-co-hexafluoropropylene)-based nanocomposites film exhibits an $${{{{{{\rm{E}}}}}}}_{{{{{{\rm{b}}}}}}}$$

E

b

of 803 MV m−1 with up to 80% enhancement, accompanied by high $${{{{{{\rm{U}}}}}}}_{{{{{{\rm{e}}}}}}}$$

U

e

= 41.6 J cm−3 and $${{{{{\rm{\eta }}}}}}\,$$
η
≈ 90%, outperforming the state-of-art nano-dielectrics. These findings enable deeper construction of nano-dielectrics and provide a different way to illustrate the intricate modification mechanism from macro to micro.
MicroRNAs within the Basal-like signature of Quadruple Negative Breast Cancer impact overall survival in African Americans
Authors: Angajala Anusha , Raymond Hughley , Muhammad Aliyu , Uddin Ahmed Md Shakir , Haleema Saadia , Haque Monira , Wang Honghe , Campbell Moray , Martini Rachel , Karanam Balasubramanian , Kahn Andrea G. , Bedi Deepa , Davis Melissa , Tan Ming , Dean-Colomb Windy , Yates Clayton 
Published: December 2022

AbstractWe previously found that QNBC tumors are more frequent in African Americans compared to TNBC tumors. To characterize this subtype further, we sought to determine the miRNA–mRNA profile in QNBC patients based on race. Both miRNA and mRNA expression data were analyzed from TCGA and validated using datasets from the METABRIC, TCGA proteomic, and survival analysis by KMPLOT. miRNA–mRNAs which include FOXA1 and MYC (mir-17/20a targets); GATA3 and CCNG2 (mir-135b targets); CDKN2A, CDK6, and B7-H3 (mir-29c targets); and RUNX3, KLF5, IL1-β, and CTNNB1 (mir-375 targets) were correlated with basal-like and immune subtypes in QNBC patients and associated with a worse survival. Thus, QNBC tumors have an altered gene signature implicated in racial disparity and poor survival.
Predictive analysis of lower limb fractures in the orthopedic complex operative unit using artificial intelligence: the case study of AOU Ruggi
Authors: Scala Arianna , Borrelli Anna , Improta Giovanni 
Published: December 2022

AbstractThe length of stay (LOS) in hospital is one of the main parameters for evaluating the management of a health facility, of its departments in relation to the different specializations. Healthcare costs are in fact closely linked to this parameter as well as the profit margin. In the orthopedic field, the provision of this parameter is increasingly complex and of fundamental importance in order to be able to evaluate the planning of resources, the waiting times for any scheduled interventions and the management of the department and related surgical interventions. The purpose of this work is to predict and evaluate the LOS value using machine learning methods and applying multiple linear regression, starting from clinical data of patients hospitalized with lower limb fractures. The data were collected at the "San Giovanni di Dio e Ruggi d’Aragona" hospital in Salerno (Italy).
Confounders mediate AI prediction of demographics in medical imaging
Authors: Duffy Grant , Clarke Shoa L. , Christensen Matthew , He Bryan , Yuan Neal , Cheng Susan , Ouyang David 
Published: December 2022

AbstractDeep learning has been shown to accurately assess “hidden” phenotypes from medical imaging beyond traditional clinician interpretation. Using large echocardiography datasets from two healthcare systems, we test whether it is possible to predict age, race, and sex from cardiac ultrasound images using deep learning algorithms and assess the impact of varying confounding variables. Using a total of 433,469 videos from Cedars-Sinai Medical Center and 99,909 videos from Stanford Medical Center, we trained video-based convolutional neural networks to predict age, sex, and race. We found that deep learning models were able to identify age and sex, while unable to reliably predict race. Without considering confounding differences between categories, the AI model predicted sex with an AUC of 0.85 (95% CI 0.84–0.86), age with a mean absolute error of 9.12 years (95% CI 9.00–9.25), and race with AUCs ranging from 0.63 to 0.71. When predicting race, we show that tuning the proportion of confounding variables (age or sex) in the training data significantly impacts model AUC (ranging from 0.53 to 0.85), while sex and age prediction was not particularly impacted by adjusting race proportion in the training dataset AUC of 0.81–0.83 and 0.80–0.84, respectively. This suggests significant proportion of AI’s performance on predicting race could come from confounding features being detected. Further work remains to identify the particular imaging features that associate with demographic information and to better understand the risks of demographic identification in medical AI as it pertains to potentially perpetuating bias and disparities.