bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluación de la escala Status Epilepticus Severity Score (STESS) como predictor de la mortalidad intrahospitalaria en pacientes con estado: Estudio observacional retrospectivo
Authors: Vidal-Mayo José de Jesús , Guzmán Ramírez Uriel , Hernández-Gilsoul Thierry , Kammar-García Ashuin , Pérez Méndez Ayari , Mancilla-Galindo Javier 
Published: August 2023

Antecedentes. El estado epiléptico (EE) es una emergencia médica caracterizada por actividad epiléptica continua o recurrente con una alta mortalidad. La escala STESS (Status Epilepticus Severity Score) permite evaluar el pronóstico de pacientes con EE.
Objetivo. Describir las características clínicas de los pacientes con EE en nuestro centro, determinar las variables asociadas a mortalidad y determinar la capacidad predictora de la escala STESS para mortalidad intrahospitalaria.
Material y métodos. Estudio de cohorte retrospectivo. Se incluyeron pacientes con diagnóstico de EE durante el periodo de 2000-2020. Se aplicó la escala pronóstica STESS a todos los pacientes. Se obtuvieron datos de las características clínicas y mortalidad intrahospitalaria. Se aplicó un análisis de regresión de Cox para determinar el riesgo de mortalidad por cada punto de la escala STESS, y se calculó el área bajo la curva ROC para determinar la capacidad de discriminación de la escala.
Resultados. Fueron incluidos 60 pacientes. La presentación clínica predominante fue el EE convulsivo generalizado en 51.7%, las etiologías más frecuentes fueron sintomáticas agudas (46.7%). La mortalidad hospitalaria fue 40%. El riesgo de mortalidad se incrementa un 38% por cada punto de STESS (B=0.38, HR=1.48, IC95%:1.13-1.94, p=0.005). El área bajo la curva ROC de la escala STESS fue 0.72 con un punto de corte óptimo ≥3 puntos para discriminación de mortalidad hospitalaria.
Conclusiones. La escala STESS se asocia significativamente con la mortalidad intrahospitalaria y puede ser usada como predictor de los desenlaces adversos en pacientes con EE.
Pengaruh Brand Image, Persepsi Harga, Dan Lifestyle Terhadap Keputusan Pembelian Pakaian Preloved Di Thriftshop Online Instagram (Studi Pada Konsumen @kenangan.mantann Di Kota Kendal)
Authors: Latifah Vika Ulfiana , Maskur Ali 
Published: August 2023

ABSTRAK
Riset ini mempunyai tujuan guna menganalisi dampak Brand Image, Persepsi Harga, serta Lifestyle pada keputusan pembelian pada Thriftshop @Kenangan.mantann. Populasi pada kajian ini ialah konsumen thriftshop @kenagan.mantann yang tinggal dikota Kendal dengan total sampel sebanyak 100 responden yang memakai pakaian preloved di thriftshop @kenangan.mantann. Penggumpulan informasi pada risrt ini memakai kuesioner dengan media Google Form. Kajian ini menerapkan metode analisa Regresi linier berganda. Riset ini bisa disimpulkan: Brand Image, Persepsi Harga dan Lifestyle mempunyai dampak positif serta signifikan pada keputusan Pembelian. Dampak paling besar pada keputusan pembelian ada pada variabel brand image dibandingkan dengan persepsi harga dan Lifestyle.
Kata kunci : Brand Image, Persepsi Harga, Lifestyle, Keputusan Pembelian

ABSTRACT
This research aims to analyze the impact of Brand Image, Perceived Price, and Lifestyle on purchasing decisions at Thriftshop @Kenangan.mantann. The population in this study are thriftshop @kenagan.mantann consumers who live in the city of Kendal with a total sample of 100 respondents who wear preloved clothes at thriftshop @kenangan.mantann. The collection of information in this research uses a questionnaire with the media Google Form. This research utilizes the technique of multiple linear regression analysis. This research can be concluded: Brand Image, Perceived Price and Lifestyle have a positive and significant impact on Purchase Decision. The biggest impact on purchasing decisions is on brand image variables compared to price perceptions and Lifestyle.
Keywords: Brand Image, Perceived Price, Lifestyle, Purchase Decision
Pengaruh Kualitas Produk , Citra Merek Dan Celebrity Endorser Terhadap Minat Beli (Studi kasus pada pengguna produk wardah kosmetik di Kota Kendal)
Authors: Lestari Yuni , Hayuningtias Kristina Anindita 
Published: August 2023

ABSTRAK
Penelitian ini bertujuan untuk menganalisis bagaimana kosmetik Wardah di Kendal, dipengaruhi oleh endorsement selebriti. Konsumen yang tertarik untuk membeli kosmetik wardah merupakan demografi penelitian ini. Seratus orang disurvei secara keseluruhan. Regresi linier berganda digunakan dalam metodologi ini. Studi ini menemukan bahwa kualitas produk dan dukungan selebriti secara signifikan meningkatkan keinginan konsumen untuk membeli produk yang diteliti. Ketertarikan terhadap kosmetik Wardah tidak berkorelasi dengan persepsi konsumen terhadap merek.
Kata kunci : kualitas produk,citra merek,celebrity endorser,minat beli.

ABSTRACT
The goal of this research is to analyze how product quality, brand image, and celebrity endorsements all work together to affect sales of wardah cosmetics in Kendal. Participants in the research are made up of those who have shown an interest in buying wardah cosmetics. In all, one hundred persons were asked their opinion. This approach relies on multiple linear regression. This study found that both product quality and celebrity endorsements significantly increased consumers' desire to buy the studied products. Interest in Wardah cosmetics does not correlate with consumers' perceptions of the brand.
Keywords: product quality, brand image, celebrity endorser, purchase intention.
Serum level of adiponectin and leptin in type 2 diabetic Cigarette smokers.
Authors: Al-Kadium Tahrir E. , Hammed Ikhlas K. , Rashid Nada F. 
Published: August 2023

Background: Cigarette smoking is the leading avoidable cause of morbidity and mortality in the general population; however its effects on people with diabetes are even more profound. The adipocytokines leptin and adiponectin play an important role in regulating glycemia, lipidemia, endothelial dysfunction, and proinflammatory mechanisms .
Objective: We aimed to investigate the profile of adiponectin and leptin in type 2 diabetic smokers and non- smokers.
Patient and Methods: Ninety overweight males attending the Teaching Laboratories, Medical City were enrolled in this study, they were arranged as 30 diabetics non smoker, 30 diabetics smokers and 30 age matched apparently healthy control group, the mean age of participants was 48.3 ± 5 years.Results: Serum adiponectin and leptin level were significantly lower in the diabetics group as compared to age and BMI matched control group (7.25 ± 0.5 Vs 9.15±0.3 and7.1 ±0.6 vs.23.5±6.3 respectively), Serum adiponectin and leptin level were significantly lower in diabetics who were smokers compared to the non smokers (5.5 ±0.7 Vs 8.8 ±0.9; p=0.005) and ( 5.02 ±0.6 Vs 8 ± 0.9;p=0.01 respectively), Adiponectin correlate negatively with BMI and positively with age .Fasting venous blood samples were collected from all the subjects. The serum was used for analyzing Fasting Blood Glucose (FBG), Total cholesterol (TC), HDL-cholesterol (HDL-C), Triglycerides (TG).HbA1c was estimated by high performance liquid chromatography, LDL-cholesterol was calculated by Friedwald and Frederickson formula. Enzyme linked immune assay were used to measure Insulin, Adiponectin and leptin . BMI was calculated as weight in kilograms divided by height in meters squared. Insulin resistance was calculated using HOMA-IR 1 Analysis of data was performed using the statistically package for social science (SPSS) version 17.0.
Conclusion: The level of serum leptin and adiponectin were lower in diabetics who were cigarette smokers
The effects of growth hormone replacement therapy on insulin, lipid profile and calcium in children with growth hormone deficiency
Authors: AL-Salami Rawia M. , AL-Jewari Majid M. , Abduljabbar Hanaa A. 
Published: August 2023

Background: Growth hormone has multiple effects on the overall form and function of growing body. Aside from these growth stimulating functions, it has marked effects on energy metabolism, it acts on fat cells to reduce the amount of stored fats, promotes protein synthesis in cells and plays a role in regulating the sugar levels in the blood.
Objective: to investigate the effect of growth hormone replacement on lipid profile, insulin level, glucose and calcium level in patients with growth hormone deficiency (GHD).
Method: A prospective study of 49 children; 37 boys and 12girls with a mean age(13.5±3.3)years attending the Children Welfare Teaching Hospital/ department of endocrinology with short stature proved to have an isolated growth hormone deficiency (other causes of short stature were excluded), with 20 healthy children as control were studied over a period of 11 months( from Oct. 2007 to Aug 2008). . Insulin level ,serum lipid ,blood glucose and serum calcium were estimated for control group and for those with isolated( GHD) prior to and post 11 months of growth hormone replacement therapy(GHRT) .
Result: Insulin levels were ( 8.1 µIU/L) in patients with GHD and elevated significantly to( 17.4 µIU/L) after GHRT, without any unfavorable effects on blood glucose. Pre treatment lipid profile values were higher (total cholesterol T-C 4.1 mmol/L ,triglyceride TG 1.5 mmol/L ,low density lipoprotein LDL 2.5 mmol/L, very low density lipoproteins VLDL 0.7mmol/L, than the control group ( T-C 3.9, TG 1, LDL 1.8, VLDL 0.5) .
Significant improvement was occurred after treatment (T-C=3.6 , TG=1.2, LDL=1.6 , VLDL=0.5); while pretreatment high density lipoproteins HDL was significantly lower (1 mmol/L) than in control (1.6) which improved significantly post treatment to (1.5) mmol/L.
Significant decrement of Post-treatment serum Ca mmol/L (2) noticed as compared to controls (2.3) and to its baseline values (2.2). Significant improvement of height= -3.7 and body mass index {BMI} =-1.1 Z score to-2.9and 0, 7 respectively were noticed post- treatment.
Conclusion: Several metabolic derangements are associated with (GHD) which could be managed effectively with (GHRT).
An analysis of the sample size requirements for acceptable statistical power in water quality monitoring for improvement detection
Authors: Wellen Christopher , Van Cappellen Philippe , Gospodyn Larissa , Thomas Janis L. , Mohamed Mohamed N. 
Published: August 2023

<p>Many water quality managers seek to demonstrate reductions in pollutants after a remedial program or policy change of some sort is implemented, but there is little information in the literature to help guide the extent of water quality sampling that is required to be confident that a change has occurred. Statistical power refers to the likelihood of avoiding a Type II error in hypothesis testing. It is critical to examine statistical power levels to ensure results are not unduly influenced by insufficient quantity of data. This study presents the first published record, to the best of our knowledge, on sample size requirements to achieve acceptable levels of statistical power in hypothesis testing of annual water quality (nutrients) in streams. We examined 13 temperate agricultural watersheds spanning a gradient of size from 11 to 16,000 km2 using data synthesized from long-term flow and water quality records. We found that achieving commonly accepted levels of statistical power (0.8) after reductions of 20% in load or flow-weighted mean concentration (FWMC) required an inordinate quantity of data (50–250 years for load, 10–120 years for FWMC), while achieving statistical power of 0.8 after reductions of 80% of load or FWMC required very little data (2–4 years for FWMC, 2–7 years for load). Load reductions of 40% required a range of 8–50 years of data depending on analyte, while FWMC reductions of 40% required 3–10 years of total phosphorus (TP) data, 5–25 years for soluble reactive phosphorus (SRP), and 2–6 years for nitrate (NO3). We examined relationships among times to achieve statistical power and a number of common landscape descriptors (discharge, baseflow index, basin size, concentration-discharge slope) and found no discernable relationships for either TP or SRP, whereas catchments with higher baseflow indices were found to have lower data requirements for achieving statistical power of 0.8 for NO3. We also show through subsampling experiments that higher frequency sampling tended to reduce data requirements to achieve acceptable statistical power, though these gains diminish as the sample frequency increases. The information presented will help those tasked with watershed monitoring to design appropriate sampling regimes to ensure adequate data are obtained to detect change.</p>
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The Role of the Nurul Hayat Gresik Amil Zakat Institute (Laz) in Empowering Rural Communities During the Covid-19 Pandemic
Authors: Hamzah Rabani Muhammad , Yasin Ach. 
Published: August 2023

The spread of the pandemic-19 has resulted in the increasing of poor residents in Gresik Regency and East Java Province, up to 2021 (gresikkab.bps.go.id and jatim.bps.go.id). seeing the magnitude impact of the Covid-19 in all aspect, efforts are needed concrete solutions that can solve these problems in the form of empowerment village community (Aprilianto, et al, 2021). This problem requires support from institutions referred to Lembaga Amil Zakat (LAZ) Nurul Hayat (Rohmah, 2021). This institution is an that collect Zakat, Infaq, and Shadaqah (SIZ) funds f rom the community (muzakki) and redistributed to the community (mustahiq) according to islamic law. The purpose of this research is to find out of the role of Lembaga Amil Zakat Nurul Hayat Gresik institution in empowering village communities during the pandemic covid-19. This research is a descriptive qualitative techniques of taking the subject using purposive sampling. Data collection techniques from interviews, observations, and documentations. The results of this study indicate that the existance of LAZ Nurul Hayat Gresik empowerment program has made the community more advanced and developed in their socio-economic field, the village community feels that they have gained more scientific insight related to entrepreneurship practices. The empowerment program from LAZ Nurul Hayat: namely Ternak Desa Sejahtera (TDS) program, and Micro, Small, Medium Enterprises (MSMEs) program.
The Effect of Project Based Learning on Digital Literacy Skills and Conceptual Understanding in an Online-Based Flipped Classroom Environment
Authors: Surur Miftahus , Dian Nurtjahyani Supiana , Agusti Agusti , Yana Indah 
Published: August 2023

The purpose of this study was to determine the effect of project-based learning on digital literacy skills and concept understanding in an online-basedflipped classroom environment. Methods used by researchers quantitative research methods. The methodological steps used by researchers are. First, researchers designed a learning design that is in accordance with the concept of PBL and online-based flipped classrooms. The research location is at STKIP PGRI Situbondo. For the population and research sample, researchers used a saturated sample of 105 students. Next, the data will be collected using test instruments. Instrument trials include: validity, reliability, difficulty, and differentiating power and continue with hypothesis testing. The results of this study are based on the results of the analysis and discussion of Project-Based Learning (PBL) learning methods that affect digital literacy skills and concept understanding in an online-based flipped classroom environment with a score of 0. 02 and 0. 03 < 0.05 then it can be concluded that there is an influence of variable X on variables Y1 and Y2. These findings also prove temporarily that PBL is suitable for use in learning through the digital world, in accordance with the main purpose of PBL whichprioritizes constructivist learning which involves the use of classical and digital books and activities in the field.
STRATEGI MANAJEMEN PRODUKSI TIM KREATIF PROGRAM ACARA PENCARIAN BAKAT Dâ€™ACADEMY ASIA DI INDOSIAR
Authors: Putra Dias Suminta Suria , Nurohmat Nurohmat , Ingratubun Adrian 
Published: August 2023

Indosiar merupakan stasiun televisi yang secara konsisten mengangkat musik dangdut, tidak saja secara nasional tetapi sudah mencapai level Asia. Program Dâ€™ Academy Asia, yang melibatkan peserta dari berbagai negara di Asia Tenggara, bahkan sudah berhasil mencapai musim ke-4. Penelitian ini bertujuan untuk menjelaskan bagaimana manajemen produksi tim kreatif program acara pencarian bakat Dâ€™Academy Asia di Indosiar. Paradigma penelitian ini adalah kontruktivis dengan pendekatan kualitatif, dan menggunakan studi kasus. Data primer diperoleh dari hasil wawancara dengan executive produser, associate produser, dan tim kreatif produksi Indosiar. Selain itu, metode analisa data dalam penelitian ini adalah secara kualitatif yang bersumber dari data primer melalui hasil wawancara dengan tim kreatif.
Untuk mendukung hasil penelitian, digunakan data sekunder dari hasil kaji pustaka. Hasil penelitian menemukan bahwa tim kreatif mempertimbangkan beberapa hal berikut ini ; pembaharuan konten dan gimmick, pemilihan bintang tamu, dan pemilihan juri. Kesimpulan yang bisa diambil berdasarkan hasil penelitian tersebut adalah manajemen produksi TV sangat penting bagi keberlangsungan suatu program TV, terutama yang disiarkan secara langsung (live). Pada akhirnya, manajemen tim kreatif tersebut mampu mempertahankan rating dan share Dâ€™ Academy Asia sampai musim ke 4.

Kata kunci : Manajemen, Produksi, Tim Kreatif, Pencarian Bakat, Dâ€™Academy.
Lactobacillus acidophilus NCFM and Lactiplantibacillus plantarum Lp-115 inhibit Helicobacter pylori colonization and gastric inflammation in a murine model
Authors: Shen Siqi , Ren FeiFei , Qin Haiming , Bukhari Ihtisham , Yang Jing , Gao Dafang , Ouwehand Arthur C. , Lehtinen Markus J. , Zheng Pengyuan , Mi Yang 
Published: August 2023

PurposeTo determine the role of Lactobacillus strains and their combinations in inhibiting the colonization of H. pylori and gastric mucosa inflammation.MethodsHuman gastric adenocarcinoma AGS cells were incubated with H. pylori and six probiotic strains (Lactobacillus acidophilus NCFM, L. acidophilus La-14, Lactiplantibacillus plantarum Lp-115, Lacticaseibacillus paracasei Lpc-37, Lacticaseibacillus rhamnosus Lr-32, and L. rhamnosus GG) and the adhesion ability of H. pylori in different combinations was evaluated by fluorescence microscopy and urease activity assay. Male C57BL/6 mice were randomly divided into five groups (uninfected, H. pylori, H. pylori+NCFM, H. pylori+Lp-115, and H. pylori+NCFM+Lp-115) and treated with two lactobacilli strains (NCFM and Lp-115) for six weeks. H. pylori colonization and tissue inflammation statuses were determined by rapid urease test, Hematoxylin-Eosin (HE) staining, immunohistochemistry, and qRT-PCR and ELISA.ResultsL. acidophilus NCFM, L. acidophilus La-14, L. plantarum Lp-115, L. paracasei Lpc-37, L. rhamnosus Lr-32, and L. rhamnosus GG reduced H. pylori adhesion and inflammation caused by H. pylori infection in AGS cells and mice. Among all probiotics L. acidophilus NCFM and L. plantarum, Lp-115 showed significant effects on the H. pylori eradication and reduction of inflammation in-vitro and in-vivo. Compared with the H. pylori infection group, the mRNA and protein expression levels of IL-8 and TNF-α in the six Lactobacillus intervention groups were significantly reduced. The changes in the urease activity (ureA and ureB) for 1-7h in each group showed that L. acidophilus NCFM, L. acidophilus La-14, L. plantarum Lp-115, and L. rhamnosus GG effectively reduced the colonization of H. pylori. We observed a higher ratio of lymphocyte and plasma cell infiltration into the lamina propria of the gastric mucosa and neutrophil infiltration in H. pylori+NCFM+Lp-115 mice. The infiltration of inflammatory cells in lamina propria of the gastric mucosa was reduced in the H. pylori+NCFM+Lp-115 group. Additionally, the expression of IFN-γ was decreased significantly in the NCFM and Lp-115 treated C57BL/6 mice.ConclusionsL. acidophilus NCFM and L. plantarum Lp-115 can reduce the adhesion of H. pylori and inhibit the gastric inflammatory response caused by H. pylori infection.
Highly effective adsorption and passivation of Cd from wastewater and soil by MgO- and Fe3O4-loaded biochar nanocomposites
Authors: Ding Hua , Liu Jie , Li Qibiao , Liu Zhichen , Xia Kai , Hu Ling , Wu Xiaoxu , Yan Qian 
Published: August 2023

Introduction: The application of Fe- (BC-Fe) and Mg-modified (BC-Mg) biochars for the remediation of heavy-metal-contaminated soil has become a research hotspot in recent years. It is critical to select suitable biochar for soil rejuvenation under the same pollution condition.Methods: In this study, the biochars were characterized by Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), and scanning electron microscopy (SEM). In addition, the adsorption and passivation effects of BC-Fe and BC-Mg were comprehensively evaluated through batch adsorption experiments and soil incubation experiments, and the effects of Cd-contaminated soil on plant growth were also demonstrated by pot experiments.Results: SEM, FTIR, and XRD showed that MgO and Fe3O4 nanoparticles were successfully loaded on the biochar surface. The maximum adsorption efficiencies of BC-Fe and BC-Mg for Cd were 52.63 and 66.23 mg g−1, which was 9.05 and 7.19 times higher than that of the original biochar (7.32 mg g−1), respectively. Soil culture experiment showed that 5% BC-Fe and BC-Mg significantly reduced soil DTPA-Cd content by 38.86% and 50.85% at 120 days, respectively. In addition, BC-Fe and BC-Mg promoted the conversion of acid-soluble Cd to the oxidizable and residual states. Pot experiments revealed that BC-Fe and BC-Mg reduced the Cd content in shoots of the maize by 3.97 and 6.09 times, respectively, and both significantly increased the dry and fresh weights of the shoots and roots of the maize plants. Moreover, BC, BC-Fe, and BC-Mg provided nutrients required for plant growth to the soil and increased the activities of soil dehydrogenase, urease, and peroxidase. The adsorption–passivation mechanism of BC-Fe on Cd mainly included electrostatic attraction, while the adsorption–passivation mechanism of BC-Mg on Cd included precipitation and ion exchange.Discussion: Overall, the results showed that BC-Mg can be used as an efficient functional material for heavy-metal pollution remediation, and this study provided guidance on the selection of passivator materials for heavy-metal-contaminated soil remediation.