bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between the quality of plant‐based diets and periodontitis in the U.S. general population
Authors: Li An , Qiu Bingjiang , Goettsch Marjolein , Chen Yuntao , Ge Shaohua , Xu Shulan , Tjakkes Geerten‐Has E. 
Published: February 2023

AbstractAimTo investigate the relationship between plant‐based diet indices (PDIs) and periodontitis and serum IgG antibodies against periodontopathogens in the U.S. population.Materials and MethodsWe analysed cross‐sectional data on 5651 participants ≥40 years of age from the Third National Health and Nutrition Examination Survey. Food frequency questionnaire data were used to calculate the overall PDI, healthy plant‐based diet index (hPDI), and unhealthy plant‐based diet index (uPDI). Periodontitis was defined using a half‐reduced Centers for Disease Control and Prevention and American Academy of Periodontology case definition. Serum antibodies against 19 periodontopathogens were used to classify the population into two subgroups using hierarchical clustering. Survey‐weighted multivariable logistic regressions were applied to assess the associations of PDI/hPDI/uPDI z‐scores with periodontitis and hierarchical clusters after adjusting for potential confounders.ResultsA total of 2841 (50.3%) participants were defined as having moderate/severe periodontitis. The overall PDI z‐score was not significantly associated with the clinical and bacterial markers of periodontitis. By considering the healthiness of plant foods, we observed an inverse association between hPDI z‐score and periodontitis (odds ratio [OR] = 0.925, 95% confidence interval [CI]: 0.860–0.995). In contrast, higher uPDI z‐score (adherence to unhealthful plant foods) might increase the risk of periodontitis (OR = 1.100; 95% CI: 1.043–1.161). Regarding antibodies against periodontopathogens, the participants in cluster 2 had higher periodontal antibodies than those in cluster 1. The hPDI z‐score was positively associated with cluster 2 (OR = 1.192; 95% CI: 1.112–1.278). In contrast, an inverse association between uPDI z‐score and cluster 2 was found (OR = 0.834; 95% CI: 0.775–0.896).ConclusionsPlant‐based diets were associated with periodontitis, depending on their quality. A healthy plant‐based diet was inversely related to an increased risk of periodontitis but positively related to elevated antibody levels against periodontopathogens. For an unhealthy plant‐based diet, the opposite trends were observed.
Risk of fetal undergrowth in the management of gestational diabetes mellitus in Japan
Authors: Kawasaki Maki , Arata Naoko , Sugiyama Takashi , Moriya Tatsumi , Itakura Atsuo , Yasuhi Ichiro , Uchigata Yasuko , Kawasaki Eiji , Sone Hirohito , Hiramatsu Yuji ,   DREAMBee study gestational diabetes mellitus group
Published: February 2023

AbstractAims/IntroductionIn Japan, the increasing frequency of underweight among women of reproductive age and the accompanying increase in the rate of low birth weight (LBW) are social issues. The study aimed to establish a prospective registry system for gestational diabetes mellitus (GDM) in Japan and to clarify the actual status of GDM according to the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria.Materials and MethodsPregnant women with gestational diabetes mellitus and those in the normal glucose tolerance (NGT) group were enrolled in the Diabetes and Pregnancy Outcome for Mother and Baby study from October 2015. Pregnant women with positive glucose screening in early and mid‐to‐late pregnancy underwent a 75 g oral glucose tolerance test by gestational week 32. Gestational diabetes mellitus was diagnosed according to IADPSG criteria. Women with a positive glucose screening test at mid‐to‐late pregnancy but NGT were enrolled as references (NGT group). Treatment for gestational diabetes mellitus and maternal and neonatal pregnancy data were prospectively collected on outcomes.ResultsIn total 1,795 singleton pregnancies (878 women with GDM and 824 NGT women) were analyzed. The risk of LBW and small‐for‐gestational age in the GDM group was significantly higher than in the NGT group. A similar relationship was found for LBW risk in the non‐overweight/obese group but not in the overweight/obese group.ConclusionsWe established a prospective GDM registry system in Japan. In the management of GDM in Japan, suppression of maternal weight gain may be associated with reduced fetal growth, especially in non‐overweight/obese women with GDM; however, further investigation is required.
Insights of Parents and Parents‐To‐Be in Using Chatbots to Improve Their Preconception, Pregnancy, and Postpartum Health: A Mixed Studies Review
Authors: Chua Joelle Yan Xin , Choolani Mahesh , Chee Cornelia Yin Ing , Chan Yiong Huak , Lalor Joan Gabrielle , Chong Yap Seng , Shorey Shefaly 
Published: February 2023

IntroductionChatbots, which are also known as conversational or virtual agents, are digital programs that can interact with humans using voice, text, or animation. They have shown promise in providing preconception, pregnancy, and postpartum care. This review aims to consolidate the insights of parents and parents‐to‐be in using chatbots to improve their preconception, pregnancy, and postpartum health.MethodsSeven electronic databases were searched from their inception dates until April 2022 (PubMed, Embase, CINAHL, PsycINFO, Web of Science, Scopus, and ProQuest Dissertations and Theses Global) for relevant studies. English language primary studies that were conducted on parents or parents‐to‐be aged ≥18 years old who had undergone interventions involving the use of any type of chatbot were included in this review. The quality of included studies was appraised using the Mixed Methods Appraisal Tool. A convergent qualitative synthesis design for mixed studies reviews was used to synthesize the findings, and results were thematically analyzed.ResultsFifteen studies met the inclusion criteria: quantitative (n = 11), qualitative (n = 1), and mixed method (n = 3). Three main themes were identified: (1) welcoming a new health resource, (2) obstacles blocking the way, and (3) moving toward a digital health era.DiscussionParents and parents‐to‐be appreciated the informational, socioemotional, and psychological support provided by chatbots. Recommendations for technological improvements in the functionality of the chatbots were made that include training sessions for health care providers to familiarize them with this new digital technology. Multidisciplinary chatbot development teams could also be established to develop more comprehensive chatbot‐delivered health programs for more diverse populations.
Retrospective study of ovarian reaction and fertility in women with discordant antimullerian hormone and follicle‐stimulating hormone/luteinizing hormone ratios during in vitro fertilization
Authors: Wang Jingjing , Lv Yuzhen , Wang XingLing , Zhu Guangli , Zhao Fang 
Published: February 2023

AbstractObjectiveThe objective of this study was to examine the predictive ability of follicle‐stimulating hormone (FSH)/luteinizing hormone (LH) ratio and antimullerian hormone (AMH) levels in the same cohort when both are inconsistent and to identify which has an excellent ability to predict live birth and ovarian response to in vitro fertilization (IVF).MethodsA retrospective cohort study was performed within 6096 IVF cycles executed between January 2016 and August 2019 at the Center for Assisted Reproduction, The Third Affiliated Hospital of Zhengzhou University, and Jiaozuo Maternity and Child Health Care Hospital. Initially, IVF cycles were classified according to basal FSH/LH ratio and AMH values, and the primary outcome was a comparison of live birth rate per cohort. Secondary outcomes included characteristics of the study individuals such as body mass index (BMI), age, antral follicle count, ovarian sensitivity index, cycle cancellation rate, and cycle outcome data.Result(s)Women with FSH/LHhigh ratio and AMHnormal levels had a meaningly higher live birth rate compared with those with FSH/LHnormal ratio and AMHlow levels (46.59% vs. 21.21%, p < 0.001). In addition, women with FSH/LHnormal ratio and AMHlow levels were found to have a higher cancellation rate in their IVF cycles (80.98%). In women with FSH/LHnormal ratio, further multivariate analysis revealed that AMH level, age, number of retrieved oocytes, and FSH dosage were relevant risk factors for live birth. The relative risk of live birth was 0.11 (95% [CI] 0.06–0.20, p < 0.001) in patients with AMHlow compared with patients with AMHnormal. It also suggested that the probability of AMHlow level may be higher as the women's age (≥35 years, odd ratio [OR] 1.94, 95% [CI] 1.44–2.61; p < 0.001) and increasing BMI (≥28 kg/m2, OR 2.38, 95% [CI] 1.33–4.27; p = 0.004). Receiver operating characteristic curve analysis indicated that AMH had higher sensitivity and specificity to predict live birth compared with FSH/LH (AUC 0.627 vs. 0.539).Conclusion(s)AMH levels can be an excellent predictor of the discrepancy between FSH/LH ratio and AMH levels regarding living birth rates in women undergoing IVF.
Publicly housed Black mothers' experiences of structural racism in their everyday lives
Authors: Letiecq Bethany L. , Williams Joseph M. , Vesely Colleen K. , Lee Jocelyn Smith 
Published: February 2023

AbstractObjectiveDrawing upon critical race and feminist theories, the objective of this qualitative study was to understand, through Black mothers' narratives, how structural racism operates within a public housing system located on the outskirts of Washington, D.C.BackgroundStructural racism has been identified as a root cause of racialized housing segregation, concentrated poverty, and health inequity—factors that disproportionately affect Black mother‐headed families living in public housing. Yet, more research is needed to delineate the underlying mechanisms of structural racism at play in public housing systems.MethodUsing a community‐based participatory action research (CBPAR) approach, the research team partnered with public housing residents and staff of a non‐profit organization to guide the study. From 2017 to 2019, community partners co‐developed the research protocol, recruited participants for in‐depth interviews (N = 15), and assisted with data analysis, interpretation, and local dissemination of findings.ResultsBlack mothers' narratives depicted in detail the structural manifestations of racism perpetuated in public housing systems, including: (a) systemic neglect; (b) economic oppression; (c) eviction threat; and (d) community surveillance. Findings suggest that structural racism is enacted and enforced by many dispersed agents of power, including street‐level bureaucrats (e.g., caseworkers and maintenance workers) and White and wealthier neighbors.ConclusionCritical perspectives and community‐driven research approaches can deepen understanding of how structural racism and institutional power relations operate to reproduce Black family marginalization within complex social systems like public housing. Directions for future research are discussed.
Depression with obstructive sleep apnea lead to high cardiovascular disease morbidity/all‐cause mortality: Findings from the SHHS cohort
Authors: Liu Hui , Peng Wanda , Zhou Lin , Shen Yi , Xu Bin , Xie Jun , Cai Tingting , Zhou Jun , Li Chong 
Published: February 2023

SummaryThe aim of this study is to explore the association between depression and obstructive sleep apnea, and cardiovascular disease morbidity/all‐cause mortality using Sleep Heart Health Study data. This post hoc analysis of a prospective study used patient data from the Sleep Heart Health Study conducted between 1995 and 1998. The association between depression and obstructive sleep apnea, and cardiovascular disease morbidity/all‐cause mortality was explored using multivariable Cox proportional hazard models. A total of 4918 participants, 656 (13.3%) with obstructive sleep apnea (obstructive sleep apnea group), 1614 (32.8%) with depression (depression group), 482 (9.8%) with depression and obstructive sleep apnea (depression and obstructive sleep apnea group), and 2166 (44%) with neither obstructive sleep apnea nor depression (health group), were included. The incidence of cardiovascular disease was 24.5%, 31.0%, 31.6% and 41.7% for healthy, depression, obstructive sleep apnea, and depression and obstructive sleep apnea groups, respectively. The risk of cardiovascular disease in depression and obstructive sleep apnea participants was increased compared with that in healthy participants, which was consistent across various definitions of obstructive sleep apnea (hazard ratio [95% confidence interval]: 1.24 [1.06–1.47]; 1.25 [1.05–1.49]; 1.28 [1.06–1.54]; 1.55 [1.22–1.96] for apnea–hypopnea index ≥ 10 per hr, 15 per hr, 20 per hr, 30 per hr, respectively). The risk of all‐cause mortality was increased in the depression and obstructive sleep apnea participants (hazard ratio: 1.46; 95% confidence interval: 1.07–1.99) compared with that in healthy participants when the definition of obstructive sleep apnea was apnea–hypopnea index ≥ 30. Participants with depression and obstructive sleep apnea might be at a greater risk of cardiovascular disease, and those with higher apnea–hypopnea index might be at a greater risk of all‐cause mortality.
CLASSIC Utterance Boundary: A Chunking‐Based Model of Early Naturalistic Word Segmentation
Authors: Cabiddu Francesco , Bott Lewis , Jones Gary , Gambi Chiara 
Published: February 2023

AbstractWord segmentation is a crucial step in children's vocabulary learning. While computational models of word segmentation can capture infants’ performance in small‐scale artificial tasks, the examination of early word segmentation in naturalistic settings has been limited by the lack of measures that can relate models’ performance to developmental data. Here, we extended CLASSIC (Chunking Lexical and Sublexical Sequences in Children; Jones et al., 2021), a corpus‐trained chunking model that can simulate several memory and phonological and vocabulary learning phenomena to allow it to perform word segmentation using utterance boundary information, and we have named this extended version CLASSIC utterance boundary (CLASSIC‐UB). Further, we compared our model to the performance of children on a wide range of new measures, capitalizing on the link between word segmentation and vocabulary learning abilities. We showed that the combination of chunking and utterance‐boundary information used by CLASSIC utterance boundary allowed a better prediction of English‐learning children's output vocabulary than did other models.
Imagining God
Authors: Wolfe Judith 
Published: February 2023

AbstractThis article interrogates the role of the human imagination in ordinary perception and orientation, in encounters with art, and in practices of faith. Philosophers and psychologists have long argued that perception is irreducibly imaginative, in the sense that to perceive intelligibly is, in part, to integrate sensory data into forms or wholes that are not simply given. The ability to do this is what continental philosophy calls ‘the imagination’, and the imagination in this sense is central to how humans apprehend and orient themselves in the world. This centrality introduces an element of risk into all human apprehension of the world, other people, and the divine, which cannot be overcome by spiritual or epistemological safeguards. Rather, such risk is inalienable, not least to a life of faith. The article discusses ways to understand and engage this dynamic, especially through theological encounters with art.
Comparing ocular biometry and autorefraction measurements from the Myopia Master with the IOLMaster 700 and the Huvitz HRK‐8000A autorefractor
Authors: Pedersen Hilde R. , Svarverud Ellen , Hagen Lene A. , Gilson Stuart J. , Baraas Rigmor C. 
Published: February 2023

AbstractPurposeTo compare axial length (AL) and corneal radius (CR) measured with the Oculus Myopia Master and the Zeiss IOLMaster 700, and cycloplegic refractive error measured with the Myopia Master and the Huvitz Auto Ref/Keratometer (HRK‐8000A).MethodsThe study included both eyes of 74 participants (16 male), with a mean (SD) age of 22.8 (3.7) years. The parameters indicated were measured under cycloplegia with these instruments: Myopia Master (AL, CR and refractive error), IOLMaster 700 (AL and CR) and HRK‐8000A (refractive error and CR). Bland–Altman plots with mixed effects 95% limits of agreement (LoA) and corresponding 95% confidence intervals were used to assess the agreement in ocular biometry between the Myopia Master and the IOLMaster 700, and for refractive error between the Myopia Master and the HRK‐8000A.ResultsThe analysis included 139 eyes, of which 52 were myopic (spherical equivalent refractive error, SER ≤ −0.50 D), 32 emmetropic and 55 hyperopic (SER ≥ 0.50 D). The 95% LoA for AL between the Myopia Master and IOLMaster 700 was −0.097 to 0.089 mm. There was no mean difference in AL [mean (SD) = −0.004 (0.047) mm, p = 0.34]. There was a significant difference in mean CR, with that measured with the Myopia Master being flatter than that found with the IOLMaster 700 [0.035 (0.028) mm, p < 0.001]. The 95% LoA for CR was −0.02 to 0.09 mm. Compared with HRK‐8000A, the Myopia Master measured a significantly more negative SER [−0.19 (0.33) D, p < 0.001], with 95% LoA of −0.86 to 0.46 D.ConclusionThe LoA for measurements of SER, CR and AL when comparing the Myopia Master with the HRK‐8000A and the IOLMaster 700 were wider than deemed acceptable for making direct comparisons. This indicates that the instruments cannot be used interchangeably in clinical practice or research.
Strategic types, implementation, and capabilities: Sustainability policies of local governments
Authors: Lee Heewon 
Published: February 2023

AbstractThe success of strategic plans is dependent on strategy implementation, yet little research has been conducted on strategy implementation relative to the strategy formulation stage. This article casts research questions on how organizational capabilities and resources affect strategy implementation, and how the implementation differs by strategic type. To address the climate change problem, local governments mobilize and allocate capabilities and resources and implement policy actions. Utilizing Miles and Snow's strategic typology, the article examines the factors for variation in implementation patterns among cities, with some implementing policies as “defenders” and others as “prospectors” across multiple policy domains. Analysis of energy policy action data from US cities reveals the distinct capabilities and resources required for the implementation of each strategic type.
Blue Light Inhibits Proliferation of Metastatic Cancer Cells by Regulating Translational Initiation: A Synergistic Property with Anticancer Drugs
Authors: Oh Phil‐Sun , Kim Eun‐Mi , Boud Fatima , Lim SeokTae , Jeong Hwan‐Jeong 
Published: February 2023

AbstractThe aim of this study was to examine the inhibitory effect of blue light (BL) on the proliferation of metastatic cancer cells and synergistic properties with chemo‐drugs. BL significantly inhibited the proliferation of B cell lymphoma (A20 and RAMOS) cells in a dose‐dependent manner. Anti‐proliferative effect of BL irradiation was identified to be associated with the inhibition of proliferating‐cell nuclear antigen expression and cell cycle by decreasing S‐phase cells. Consistent with its inhibitory effects, BL irradiation at 20 J/cm2 daily for 10 days inhibited metastasis of cancer cells which were distributed and invaded to other organs including bone marrow, liver, kidney, etc., and induced paraplegia, thereby leading to an increased survival rate of tumor‐bearing mice. Anti‐proliferative activity of BL was expanded in solid tumor cells including pancreatic carcinoma (Mia PaCa‐2, PANC‐1), lung carcinoma A549 and colorectal carcinoma HCT116 cells. Additionally, combination with chemo‐drugs such as 5‐FU and gemcitabine resulted in an increase in the anti‐proliferative activity after BL irradiation accompanied by regulating mRNA translational process via inhibition of p70S6K, 4EBP‐1 and eIF4E phosphorylation during cellular proliferation. These results indicate the anti‐metastatic and photo‐biogoverning abilities of BL irradiation as a potent therapeutic potential for repressing the progression of tumor cells.
Real‐world effectiveness of preemptive therapy (PET) for cytomegalovirus (CMV) disease prevention in CMV high‐risk donor seropositive/recipient seronegative (D+R‐) liver transplant recipients (LTxR)
Authors: Doss Kathleen M. , Kling Catherine E. , Heldman Madeleine R. , Singh Nina , Wagener Marilyn , Rakita Robert M. , Fisher Cynthia E. , Limaye Ajit P. 
Published: February 2023

AbstractBackgroundDespite superiority of preemptive therapy (PET) compared to universal prophylaxis for prevention of cytomegalovirus (CMV) disease in the CAPSIL randomized trial among CMV D+R‐ liver transplant recipients (LTxRs), real‐world effectiveness may be lower because of logistical concerns about feasibility of PET.MethodsWe retrospectively assessed PET as standard clinical care at a single transplant center among 50 consecutive adult CMV D+R‐ LTxRs undergoing a first liver transplant between 4/4/2019 and 5/18/2021 and compared outcomes and adherence to those randomized to PET in the CAPSIL study (N = 100). The primary outcome was CMV disease and secondary outcomes were biopsy‐confirmed acute allograft rejection, retransplant, invasive fungal infections, and death, all assessed by 1‐year post‐transplant. Exploratory outcomes included virologic parameters and measures of adherence to protocol‐specified CMV qPCR monitoring.ResultsBaseline characteristics were similar between groups. The cumulative incidence of CMV disease at 1‐year post‐transplant was 4/50 (8%) versus 9/100 (9%) in the real‐world and CAPSIL cohorts, respectively, p = 1.0. The rate of breakthrough CMV disease during the 100‐day PET period was low (2/50 [4%]) and similar to the PET cohort from the CAPSIL study (3/100 [3%]). All secondary and exploratory outcomes were not significantly different between the real‐world and CAPSIL PET cohorts.ConclusionsIn this first reported study of real‐world PET, the feasibility and effectiveness for CMV disease prevention and for other clinical outcomes in CMV D+R‐ LTxRs were similar to those reported with PET in a clinical trial. Additional studies to confirm feasibility and generalizability in other settings are warranted.
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