bluuebunny/crossref_metadata_2025_split huggingface dataset:
Inclusiveness of Financial Activities of Hotel Institutions during the Covid-19 Pandemic
Authors: Melnychuk Yuliia , Chvertko Liudmyla 
Published: December 2022

Scientific work on “Inclusiveness of Financial Activities of Hotel Institutions During the Covid-19 Pandemic” aims to conduct a financial analysis of the state of the hotel services market in Ukraine and the world during the period of active progression of the Covid-19 virus infection. The purpose of the article. The aim of the work was to study the peculiarities of the financial development of the hotel industry in the pandemic in the world and in Ukraine. The methodology. The totality of research methods is a methodology for analyzing and organizing the main legislative acts and laws, namely the methods of generalization, comparison, chronology, analysis and generalization. Segment diagramming, elements of financial analysis, as a digital display of the state of the economic level of development are used to visualize the state of the hotel business market. The results of the research. The study analyzes the level of change in sales revenue from the hotel business in Ukraine. The regions of Ukraine were divided into the main tourist regions and the structure of accommodation facilities by types and specialized accommodation facilities have been developed. The scientific work considers the hotel industry as elements of the market of services of Ukraine, so the distribution of accommodation is divided into in the following regions: central region, northern region and western and southern regions. The location of hotel business establishments is appropriately structured. Conclusions that were made indicate the need to improve the quality of services while expanding their range, which is due to the ever-increasing demands of consumers in accordance with the requirements of advanced technologies. A significant expansion of the range of accommodation (apartments, villas, holiday homes, country and guest houses, chalets, etc.) will best guide different groups of tourists and diversify the types of recreation. The presented paper depicts relevant and necessary research that will help hotel business leaders to respond in a timely manner to financial threats. During the Covid-19 pandemic, it is important to monitor the state of the Ukrainian services market, timely implement all possible security measures and prevent the impact of adverse factors on the development of the hotel business.
Heatstroke and brachycephalic dogs – is there an increased risk?
Authors: Ewers Clark Anna 
Published: December 2022

PICO question
Do dogs that are brachycephalic have an increased risk for developing heat-related illness compared to dogs that are not brachycephalics?

Clinical bottom line
Category of research
Risk.
Number and type of study designs reviewed
Four studies were critically appraised. Three of these were cohort studies, one was a case-control study.
Strength of evidence
Moderate.
Outcomes reported
Brachycephalic dogs are at increased risk of developing heat-related illness and brachycephalic breeds are over-represented in presentations for heatstroke. Other factors named, such as body weight, also contributed to the risk of developing heat-related illness.
Conclusion
Dogs that are brachycephalic are likely to have an increased risk for developing heat-related illness compared to non-brachycephalic dogs.

How to apply the evidence in practice
The application of evidence into practice should take into account multiple factors, not limited to: individual clinical expertise, patient’s circumstances and owners’ values, country, location or clinic where you work, the individual case in front of you, the availability of therapies and resources.
Knowledge Summaries are a resource to help reinforce or inform decision making. They do not override the responsibility or judgement of the practitioner to do what is best for the animal in their care.
PROSPECTS OF INTEGRATION OF NANOTECHNOLOGY TO ANTIMALARIAL HERBAL REMEDIES FOR IMPROVED THERAPEUTIC EFFICACY – A CONCISE REVIEW
Authors: ONYEJI Cyprian   .O. 
Published: December 2022

Background: The therapeutic utility of herbal medicinal products including antimalarial herbal remedies has been hampered by some unfavorable biopharmaceutical properties of the bioactive constituents such as low aqueous solubility, poor oral bioavailability, poor intestinal permeability and large molecular size. Al these biopharmaceutical issues are responsible for observed reduced in vivo efficacy of some herbal products compared to their in vitro efficacy. These drawbacks can by countered by the integration of nanotechnology. The present article identified the various documented nanosystems and examined the recent efforts in the deployment of nanotechnology in formulations of antimalarial herbal medicines for improved therapeutic efficacies. Also safety considerations in clinical applications of nanoformulations were highlighted.
Methods: The information was acquired from an extensive literature searching of electronic databases such as Science-Direct, PubMed, and Google-Scholar to obtain appropriate articles made in the English language which were published up to 2022, using a combination of relevant keywords.
Results: Only very few herbal antimalarial remedies such as extracts of Azadirachta indica, Momordica charantia, Curcuma longa, and Artemisia species have been nanoformulated and evaluated for antimalarial efficacy. In all these studies, the drug-loaded nanoformulations exhibited significantly higher in vitro and/or in vivo antimalarial efficacy. The different nanoformulations of antimalarial herbal remedies that have been reported include nanoparticles of lipid-based, cyclodextrin, chitosan/lecithin , liposomes, nanosuspension, nanoemulsions, and metal-based nanoparticles..
Conclusion: Different types of nanoformulations of herbal antimalarial drugs have been reportedly prepared by different techniques and these offer advantages of improved efficacies. Safety concerns present a hurdle to clinical applications.
A Review of Abductor Tendon Tears
Authors: Dove James H. , Lemme Nicholas J. , Modest Jacob M. , Talley-Bruns Rachel C. , Tabaddor Ramin R. , Fadale Paul D. 
Published: December 2022

» Greater trochanteric pain syndrome consists of a group of associated conditions involving the lateral hip that can be debilitating to patients, mostly women between ages 40 and 60 years.» Abductor tendon tears are becoming a more recognized cause of lateral hip pain in patients without hip osteoarthritis.» Diagnosis of this condition is critical to patient care because misdiagnosis often leads to unnecessary prolonged pain and even unnecessary procedures that address different pathologies.» Treatment strategies consists of nonoperative modalities such as nonsteroidal anti-inflammatory medications, corticosteroid injections, and physical therapy, but for refractory cases, surgical techniques including repair, augmentation, and reconstruction have been well-described in the literature providing patients with acceptable outcomes.
TINGKAT PENGEMBALIAN INVESTASI PENDIDIKAN PADA LULUSAN FAKULTAS EKONOMI DAN MANAJEMEN (Studi Kasus Lulusan yang Bekerja pada Sektor Formal)
Authors: Gusparima Hilma , Darmawan Refianto Damai , Kartika Lindawati 
Published: December 2022

Pengembalian investasi pendidikan di Indonesia menunjukkan angka yang konsisten dan semakin meningkat untuk jenjang pendidikan yang semakin tinggi. Namun jika melihat data, Angka Partisipasi Kasar (APK) di Indonesia mengalami penurunan pada jenjang pendidikan. Sehingga tujuan penelitian ini adalah untuk mengetahui hasil Return on Higher Education Investment (ROHEI) dan kelayakannya pada lulusan Fakultas Ekonomi dan Manajemen IPB sebagai perguruan tinggi negeri di wilayah Jabodetabek. Jenis data yang digunakan dalam penelitian adalah data kuantitatif dan kualitatif melalui data primer dan sekunder. Metode penentuan dan penarikan sampel yang digunakan adalah nonprobability sampling dan purposive sampling. Jumlah sampel dalam penelitian ini sebanyak 150 orang. Metode analisis yang digunakan adalah analisis deskriptif dan pengembalian investasi. Analisis deskriptif digunakan untuk mengolah data pada karakteristik responden. Adapun analisis pengembalian investasi berupa benefit cost ratio (BCR), rate of return (ROR), cost benefit analysis (CBA), Payback Period (PP), net present value (NPV), dan internal rate of return (IRR) serta analisis loyalitas lulusan menggunakan net promoter score (NPS). Hasil penelitian ini menunjukkan, bahwa kelayakan investasi pendidikan dari gaji responden dinyatakan layak namun hasil penghitungan terkait nilai manfaat berdasarkan tabungan dinyatakan tidak layak. Loyalitas responden terhadap Fakultas Ekonomi dan Manajemen mayoritas berada dalam kategori passive. Kata Kunci: Investasi, Lulusan, Pendapatan Pendidikan, ROHEI, Tabungan
Evaluation of the Autof ms1000 mass spectrometry for rapid clinical identification of filamentous fungi
Authors: Ao Keping , Li Xiaohan , Zhang Weili , Chen Zhixing , Liu Ya , Shu Ling , Xiao Yuling , Wu Siying , Xie Yi , Kang Mei 
Published: December 2022

Abstract
Background
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has revolutionized microbial identification; however, there is a paucity of data on its performance characteristics to identify filamentous fungi. The objective of our study was to evaluate the accuracy of the Autof ms1000 mass spectrometry for filamentous fungi identification in the clinical microbiology laboratory.
Results
Among 95.28% (101/106) that were identified using Autof ms1000 systems at Genus/Species, 76.41% (81/106) were correctly identified at the species level. In addition, a new rapid formic acid extraction method with simple pretreatment for filamentous fungi was developed to save time and obtain accurate results.
Conclusions
The Autof ms1000 mass spectrometer showed to be a useful instrument for filamentous fungi identification. Nevertheless, up-gradation of the database is recommended for the correct identification of rare strains.
Synthesis of Vitamin D Conjugated Calcium Carbonate Nanoparticles and Their Application on Selected Cell Lines
Authors: Shaukat Khazaima , Riaz Naveeda , Manzoor Sobia , Urooj Sidra , Fatima Moaiz 
Published: December 2022

Abstract

Cancer is a worldwide conundrum and the leading cause of death. Drug delivery to cancer cells has been changed thanks to nanotechnology. In this study, calcium carbonate nanoparticles were used to provide Vitamin D to the breast cancer cell line MCF-7. The nanoparticles that are used, were prepared by using binary solvents as precipitates and swirling them continuously with a magnetic stirrer. FTIR and XRD measurements confirmed the production of nanoparticles. SEM analysis revealed that nanoparticles have a spherical morphology. According to a UV-Visible spectrophotometer, calcium carbonated nanoparticles had an encapsulation effectiveness of 80% for vitamin D. At a dosage of 2000g/ml, vitamin D conjugated nanoparticles showed a good cytotoxic activity, reducing the viability percentage of cancer cells by up to 11%. As a result, it was found to be helpful in slowing cancer cell development. The findings showed that CaCO3 nanoparticles can effectively supply vitamin D to cancer cells while also inhibiting cancer cell proliferation.
Putting numbers on timber illegality risk: the case of ipê in Pará
Authors: França Caroline Sartorato Silva , Persson Martin , Carvalho Tomás , Lentini Marco 
Published: December 2022

Abstract
Illegal logging remains widespread across the tropics, causing extensive forest degradation and trade in illegal timber products. By adapting environmentally extended input-output modeling to timber originating from Brazilian native forests, we demonstrate how distinct illegality risks can be mapped and quantified at species-level, across the supply-chain. We focus on high-value ipê from the Amazon state of Pará, a leading producer of timber and contested forest frontier. Data on logging permits and state- and national-level Document of Forest Origin are used to estimate illegality risks due to missing or invalid logging permits, overstated ipê yields, and discrepancies resulting from missing inflows of legal timber. We find that less than one fourth of all ipê volume entering supply-chains between 2009-2019 is risk-free and highlight diversified strategies for laundering of illegal timber are across geographies, information that can be leveraged to improve implementation and enforcement of existing forest regulations.
The International Spinal Cord Injury Pain Basic Data Set (Version 3.0)
Authors: Widerstrom-Noga Eva , Biering-Sørensen Fin , Bryce Thomas , Cardenas Diana , Finnerup Nanna , Jensen Mark , Richards John Scott , Rosner Jan , Taylor Julian 
Published: December 2022

Abstract
Study design: Expert opinion, feedback, revisions, and final consensus.
Objectives: To update the International Spinal Cord Injury Pain Basic Data Set (ISCIPBDS version 2.0) and incorporate suggestions from the SCI pain clinical and research community with respect to overall utility.
Setting: International
Methods: The ISCIPBDS working group evaluated these suggestions and made modifications. The revised ISCIPBDS (Version 3.0) was then reviewed by members of the International SCI Data Sets Committee, the American Spinal Injury Association (ASIA) Board, the International Spinal Cord Society (ISCoS) Executive and Scientific Committees, individual reviewers and societies, and posted on the ASIA and ISCoS websites for one month to elicit comments before final approval by ASIA and ISCoS.
Results: The ISCIPBDS (Version 3.0) was updated in order to make the dataset more flexible and useful: 1. The assessment can be based on the patient’s perception of several of his/her “worst” pain(s) or based on the International SCI Pain (ISCIP) Classification-defined or other pain types, depending on the specific research questions or clinical needs. 2. Pain interference should usually be rated for overall pain but may also be used for specific pain problems if needed. 3. An optional pain drawing was added to complement the check box documentation of pain location. 4. Data categories consistent with the Extended Pain Dataset list of current treatments were added. 5. Several new training cases were added.
Allele-specific hormone dynamics in highly transgressive F2 biomass segregants in sugarcane (Saccharum species)
Authors: Ain Noor-ul-Ain , Zhang Xingtan , Habiba Habiba , Lin Jishan , Ming Ray 
Published: December 2022

Abstract
Background
Sugarcane is a competitive candidate to serve as feedstock for biofuel production worldwide. Plant hormones play an important role in growth and development and regulate biomass yield. Understanding hormonal dynamics and their regulation is critical for increasing sugarcane biomass. To enhance our understanding of biological pathways involved in biomass accumulation, transcriptome analysis of highly segregating F2 introgression hybrids derived from the cross of Saccharum officinarum'LA Purple' and wild S. robustum 'MOL5829' was performed in this study. Recently sequenced information rich allele-specific genome of S. officinarumserved as a reference to identify differentially regulated genes in two groups of extreme segregants of biomass.
Results
Overall, 8059 differentially expressed genes (log2FC > 2) were grouped into distinct categories viz. Gene Models (21.5%) (GMs), alleles (68%), paralogs (10%) and tandemly duplicated genes (0.14%). KEGG analysis showed enrichment of auxin (IAA), jasmonic acid (JA) and abscisic acid (ABA) related pathways and interesting regulatory roles of three hormone repressor gene families (Aux/IAA, PP2C, and JAZ) of IAA, ABA and JA, respectively. Signaling pathways of these hormones indicated down-regulation of AUX/IAA and PP2C and up-regulation of JAZ repressor genes in high biomass group controlling the expression of downstream growth and development genes. Endogenous hormone levels show higher IAA and ABA contents in high biomass and vice versa for JA. Weighted co-expression network analysis (WGCNA) demonstrated high connectivity between identified hormones related key genes and cell wall structural genes in high biomass genotypes. FPKM and RT-PCR based expression analysis showed the up-regulation of carbohydrate structural genes and down regulation of inflorescence and senescence related genes, which indicated an extended vegetative growth phase in high biomass genotypes. Furthermore, high biomass group displayed modulated regulation of hormones which was achieved by the cumulative expression of Gene Models (GMs), dominant alleles, paralogs, and tandemly duplicated genes.
Conclusion
Our data revealed that activators and repressors of disparate hormone (IAA, JA, and ABA) signaling pathways are the points of hormone crosstalk in contrasting biomass F2 segregants and could be applied for engineering high biomass acquiring varieties.
Comparative Evaluation of RBPT, I-ELISA, and CFT for the Diagnosis of Brucellosis and PCR Detection of Brucella species from Ethiopian Sheep, Goats, and Cattle sera
Authors: Legesse Abinet , Mekuriaw Aregitu , Gelaye Esayas , Abayneh Takele , Getachew Belayneh , Weldemedhin Wubet , Tesgera Takele , Deresse Getaw , Birhanu Kenaw 
Published: December 2022

Abstract
Method: Brucella is an intracellular bacterium that affects both animals and humans. The aim of this study was to compare brucellosis diagnostic methods such as RBPT, I-ELISA, CFT and PCR detection of Brucella species. A total of (552) Sheep, (1345) Goats, and (420) Cattle sera samples were collected with no history of vaccination from brucellosis reported regions of Ethiopia. All sera samples were subjected to comparative serological assays. Post- cross tabulation, sensitivity and specificity were determined using Receiver Operating Characteristics (ROC) curve analyses software. Fifty-four sero-positive sera samples were also subjected to PCR amplification targeting Brucella Genus-specific, as well as B. abortus, and B. melitensis species specific primers.
Results: Among 2317 sera samples subjected to comparative serological diagnostic tests (RBPT, I-ELISA and CFT), 189 (8.16 %) for RBPT, 191 (8.24 %) for I-ELISA and 48 (2.07 %) on CFT were found to be positive. Sensitivity on RBPT was 100 % with (95%) in Sheep, 100% (95%) Goats and 74% (95%) Cattle. Specificity on RBT was 98.69% (95%), 99.28% (95%), 100 (95%) in Sheep, Goats and Cattle, respectively. Sensitivity on CFT was 4% with (95) in Sheep 9.65 (95%) Goats and 72 (95%) Cattle. Specificity on CFT was 100 % (95%) for each Sheep, Goats and Cattle. In PCR amplified product analyses, a 223bp in Brucella genus-specific and 156bp B.abortus species specific were detected from all study animals. However, B. melitensis was not detected in all sera samples.
Conclusion: In this study Indirect-ELISA was found to be the most sensitive and specific test. RBPT was also sensitive enough to detect all Brucellosis-infected Sheep and Goats. However, this test showed false positive in Sheep and Goats and false negative results in cattle. Therefore, RBT should be complemented with ELISA to solve problems associated with sensitivity and specificity of RBT. PCR assay employed in this study confirmed the presence of B. abortus in small and large ruminants consistent to the study sites. This study is the first report on the detection of B.abortus on small ruminants’ serum in Ethiopia. We could detect B. abortus in non-preferred hosts. The findings suggest further extensive works are required to determine the genetic diversity of Brucella species and understand their molecular epidemiology at national level to design cost effective prevention and control methods.
Can digital finance alleviate the resource curse? Evidence from Resource-based Cities in China
Authors: Huang Xinpeng 
Published: December 2022

Abstract
This paper investigates how digital finance alleviates the resource curse effect from resource-based cities in China. This paper selects the data from 88 resource-based cities in China from 2011 to 2019 to construct the econometric model test hypothesis. The results show that: (1) Resource curse does exist in Chinese resource-based cities. (2) Digital finance can alleviate the resource curse of resource-based cities in China, and this effect has two significant thresholds. (3) The heterogeneity test results show that digital finance's mitigation effect on the resource curse significantly differs in cities with different environmental regulation intensities and resource abundance. (4) Using the implementation of the broadband China strategy as the proxy variable of digital finance for the robustness test, the above conclusions are still robust. This paper considers the impact of digital upgrading on the financial industry and further studies the mitigation effect of digital finance on the resource curse. It provides a new perspective to study the recent changes in traditional issues in the digital era.
Unconventional quantum criticality in a non-Hermitian extended Kitaev chain
Authors: S Rahul , Roy Nilanjan , R Ranjith Kumar , Kartik Y R , Sarkar Sujit 
Published: December 2022

Abstract
We investigate the nature of quantum criticality and topological phase transitions near the critical lines obtained for the extended Kitaev chain with next nearest neighbor couplings and non-Hermitian chemical potential. We surprisingly find multiple gap-less points, the locations of which in the momentum space can change along the critical line unlike the Hermitian counterpart. The interesting simultaneous occurrences of vanishing and sign flipping behavior by real and imaginary components, respectively of the lowest excitation is observed near the topological phase transition. Introduction of non-Hermitian factor leads to vanishing of a critical line and hence, reduced number of multi-critical points as compared to the Hermitian case. The critical exponents obtained for the multi-critical and bi-critical points show a very distinct behavior from the Hermitian case. Interestingly, we further observe violation of Lorentz invariance throughout the criticality in our non-Hermitian model.
Expectations of nursing home residents and their family members during the COVID-19 epidemic: A qualitative study
Authors: Cui Baojuan , Li Hui , Cheng Yan , Wang Jinmei , Sun Qiangsan , Jia Yuxiu 
Published: December 2022

Abstract
Background
COVID-19 has spread worldwide. Older people are at the greatest risk of contracting and dying from the virus. Nursing homes are densely populated places for older adults who are generally vulnerable and at high-risk. Although Chinese nursing homes have been trying to protect their residents, the needs and expectations of the residents and their families have been ignored. The aim of this study was to explore and better understand the expectations of nursing home residents and their family members during the COVID-19 epidemic in China.
Methods
Data was collected via face-to-face semi-structured interviews with nursing home residents and focus group online interviews with family members between June 2021 and February 2022. Data analysis followed inductive content analysis.
Results
16 residents and 24 family members were interviewed. Four themes with 11 sub-themes were identified from the descriptions of participants. Their expectations were mainly focus on prevention and control measures for COVID-19, medical capacity of nursing homes, health education and expectations for some aged care policies.
Conclusions
In the face of concerns about the impact of COVID-19 on nursing homes, we sought to bring firsthand perspectives to the forefront by interviewing residents and their family members about their expectations to address this issue. Our findings provide important areas on which should be focused and may improve the sense of gain, happiness, and security of nursing home residents during the COVID-19 epidemic.