bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk factors analysis of hypokalemia after radical resection of esophageal cancer and establishment of a nomogram risk prediction model
Authors: Yan Guanqiang , Li Jingxiao , Su Yiji , Li Guosheng , Feng Guiyu , Liu Jun , Gao Xiang , Zhou Huafu 
Published: January 2025

ObjectiveThis study aimed to explore the risk factors of hypokalemia after radical resection of esophageal cancer (EC) and establish a nomogram risk prediction model to evaluate hypokalemia risk after esophagectomy. Thus, this study provides a reference for the clinical development of intervention measures.MethodsClinical data of EC patients who underwent radical surgery from January 2020 to November 2022 in the First Affiliated Hospital of Guangxi Medical University were retrospectively collected. The relevant variables were screened using multivariate logistic regression analysis with IBM SPSS 25.0 and R 4.2.0 software, and a nomogram for predicting hypokalemia risk was established. The established nomogram was evaluated by receiver operating characteristic (ROC), calibration, and decision curves. The model was also internally validated by 1000 bootstrap resampling methods.ResultsAfter radical EC resection, the incidence rate of hypokalemia in 213 patients was 19.2% (41/213). The hemoglobin levels, total serum protein, serum albumin, calcium ion concentration, direct bilirubin, prothrombin time (PT), and activated partial thromboplastin time (APTT) were related (p &lt; 0.05). The multivariate logistic analysis showed that the white blood cell count, serum albumin level, direct bilirubin, and operation time were risk factors for hypokalemia after radical EC resection (p &lt; 0.05). The area under the ROC curve (AUC) was 0.764, demonstrating the good discriminative ability of the established nomogram for hypokalemia prediction. The calibration curve showed a good fit between the predicted and actual observed probabilities. The model maintained a high C-index in the internal validation (C-index = 0.758), supporting that the nomogram can be widely used for hypokalemia prediction.ConclusionThe prediction model for hypokalemia risk with individualized scores based on the patient's white blood cell count, serum albumin level, direct bilirubin, and operation time can screen out high-risk patients who might develop hypokalemia. It is of certain reference value for clinicians to screen and follow up with patients with emphasis and to formulate preoperative and postoperative intervention strategies.
Documentation of ethnoveterinary knowledge and alternative practices for cattle tick control in Sekhukhune District, Limpopo Province, South Africa
Authors: Phaahla Confidence Semakane , Shai Jeremiah Leshweni , Maduna Vincent , Moropeng Resoketswe Charlotte , Magano Solomon Ramagoai 
Published: January 2025

IntroductionThe integration of traditional plant-based methods for controlling ectoparasites in the primary healthcare of livestock is progressively emerging as a crucial intervention to enhance livestock productivity in regions with limited resources, particularly in smallholder farming areas facing resource constraints. In Sekhukhune District, where livestock plays a vital role in rural livelihoods, cattle ticks present a significant challenge to cattle farming. This study aimed to document the ethnoveterinary practices employed by local communities to control cattle ticks, highlighting the use of alternative methods rooted in indigenous knowledge (IK).MethodsData were collected using a purposive sampling method to select traditional livestock keepers, herders, and community elders to uncover the plant-based treatments and management strategies used in tick control. In addition, a semi-structured questionnaire and a guided field survey were employed to collect data.ResultsA total of 250 participants, with an age range from 18 to over 60 years, were recruited. The result revealed that the elder participants, over 60 years of age, were more knowledgeable compared to the youth and adults. Furthermore, 28 plant species with potential acaricidal properties and other methods aimed at controlling cattle tick infestations were documented. Cissus quadrangularis was the most frequently cited species, which was widely distributed throughout the district.ConclusionIn addition, these results are framed within the larger context of sustainability, promoting eco-friendly cattle farming practices in Sekhukhune District while reducing reliance on conventional acaricides. By documenting this ethnoveterinary knowledge, the study contributes to the preservation of indigenous knowledge while advocating for sustainable approaches to livestock health management in rural areas. The study concludes with valuable insights into the selected local community’s traditional methods of managing tick infestations. Furthermore, the study underscores the significance of preserving and understanding indigenous knowledge in livestock health management, particularly in regions where conventional veterinary approaches may face challenges.
Does perioperative electroacupuncture reduce postoperative pain in dogs undergoing ovariohysterectomy?
Authors: Iwe Celine , Schiele Anika , Passenegg Vanessa , Corona Daniele , Bettschart-Wolfensberger Regula , Heitzmann Vanessa 
Published: January 2025

IntroductionThis study aimed to investigate the analgesic efficacy of perioperative electroacupuncture in fifty-six healthy female dogs undergoing ovariohysterectomy as part of a catch-neuter-release project.Materials and methodsTen minutes after sedation with 20 μg/kg medetomidine combined with 0.3 mg/kg butorphanol intramuscularly, the dogs were randomly allocated into two groups and received either electroacupuncture (EA, n = 27) or sham acupuncture (C, n = 29) treatment for 10 min (after sedation until the end of the surgery) at 6 different acupuncture points LI-4 (Large intestine 4), LIV-3 (Liver 3), ST-36 (Stomach 36), SP-6 (Spleen 6) bilateral. After administration of 0.2 mg/kg meloxicam and anesthesia induction with 2 mg/kg ketamine intravenously, ovariohysterectomy was performed by the same experienced surgeon using a midline surgical approach in dorsal recumbency. Pain was evaluated by two blinded and independent anesthetists using the Short Form of the Multimodal Glasgow Composite Pain Scale (mCMPS-SF) before sedation (T0), and three (T3), six (T6), and 24 h (T24) after anesthesia induction.ResultsPostoperative pain scores did not differ significantly between the groups (p = 0.36), but increased significantly three (T3) (p = 0.001) and six (T6) (p = 0.001) hours after surgery compared to before sedation and 24 h postoperative in both groups. Three hours after surgery (T3), 89.4% and six hours postoperatively (T6), 71.4% of the dogs in both groups exceeded the analgesic intervention threshold of the mCMPS-SF, indicating the need for rescue analgesia.DiscussionThe results of the study indicate that perioperative electroacupuncture treatment did not improve postoperative pain in dogs undergoing ovariohysterectomy. Therefore, a 10-min electroacupuncture treatment may be insufficient to provide effective postoperative analgesia. The pain assessment in feral dogs was notably impacted by anxious behavior, which may have influenced the final outcome The pain threshold was exceeded in ¾ of the dogs in the early postoperative phase (T3, T6), suggesting that the widely used anesthesia protocol consisting of butorphanol, ketamine and medetomidine in combination with meloxicam may not provide long-lasting and sufficient pain relief.
Pleurotus ostreatus: Nutritional Enhancement and Antioxidant Activity Improvement Through Cultivation on Spent Mushroom Substrate and Roots of Leafy Vegetables
Authors: Melanouri Eirini-Maria , Diamantis Ilias , Dedousi Marianna , Dalaka Eleni , Antonopoulou Paraskevi , Papanikolaou Seraphim , Politis Ioannis , Theodorou Georgios , Diamantopoulou Panagiota 
Published: January 2025

Agricultural residues, including Pleurotus ostreatus spent mushroom substrate (SMS) and roots of (hydroponic) leafy vegetables (RLV), were tested in various proportions as substrates in new P. ostreatus cultivations, where wheat straw was the control. The impact of SMS and RLV was first evaluated by the mycelial growth rate (Kr, mm/day). Afterwards, mushroom cultivation was conducted in bags, where production characteristics like earliness (the time from substrate inoculation to first harvest) and biological efficiency (BE %, the ratio of fresh mushroom weight to dry substrate weight × 100) were examined. The study also evaluated mushroom quality, nutritional composition and bioactive content. The highest intra-cellular polysaccharide (IPS) value (50.93%, w/w) was observed in the substrate containing SMS 90%, while combining SMS with RLV resulted in higher IPS values compared to mixtures that also included wheat bran (WB) and soybean flour (SF). Furthermore, the use of RLV reduced the fat content compared to the control substrate, except in the case of the SMS 50%–RLV 40% substrate, where the highest fat content was observed in the produced mushrooms (4.68% w/w). Additionally, the protein content increased with the use of RLV. The highest triterpene content was found in the SMS 90%–RLV 10% (11.52 ursolic acid mg/g d.w.). However, the control substrate exhibited the fastest Kr (6.5 mm/d), as well as the highest BE (87.8%) and total phenolic compound value (30.31 mg GAE/g d.w.). Significant antioxidant activity was observed in all extracts, while the total flavonoid content was low. Glucose was the dominant monosaccharide (over 51.5%, w/w), and linoleic acid (18:2; over 57.05%, w/w) was the primary fatty acid across all mushrooms. This study also enhances our knowledge by which SMS and RLV influence the NFE2L2/HMOX-1 molecular pathway, thereby affecting specific antioxidant-related genes. These effects were observed through the impact of P. ostreatus protein and carbohydrate extracts on LPS-challenged THP-1-derived macrophages. A positive impact on the gene expression of HMOX1, CAT and NFE2L2 during incubation with the aforementioned samples was observed. These findings support the sustainable use of agricultural by-products in mushroom cultivation, offering an environmentally friendly approach while producing valuable products like mushrooms.
Electron-beam induced electro-force field display for a dynamical biomanipulation system
Authors: Ichinohe Kain , Sasaki Ken , Hoshino Takayuki 
Published: January 2025

Abstract
Molecular-computer interfaces are expected to provide valuable biomolecular applications by interconnecting the nanoscale molecular world to cyber space. We proposed an electron beam (EB)-induced dynamical display of pure electrophoretic-force field, and experimentally demonstrated interactive motion control with the nano resolution electro-force field display. The displayed electro-force fields were performed with nanoscale resolution and instantaneously changed the geometrical form by EB scanning trajectory, which is named the virtual cathode (VC). The surface modification of the display successfully suppressed electroosmotic flows and improved nanoscale precision control via geometric form effects owing to the sharp edge part of the VC patterns, which enhanced the electrophoretic-force field at the sharp edge parts. Finally, we demonstrated the performance of the dynamically displaying force field by implementing an interactive nano video game on the display. These results indicate that the intuitive electrophoretic-force field display represents a powerful nanotool for enhancement of real-time biomolecular machining technology.
Problematika Keterwakilan Perempuan Paling Sedikit 30% dalam Pencalonan Anggota Legislatif
Authors: Agatha Insani Tiara , Mustafid Mustafid , Anwar Alfiansyah 
Published: January 2025

Permasalahan gender telah menjadi diskursus tersendiri dalam sistem hukum Indonesia, yang bahkan telah menyentuh aspek keanggotaan dan keterwakilan perempuan di parlemen akibat fenomena relatif rendahnya keterwakilan anggota perempuan di parlemen. Oleh karena itu, pemerintah berupaya mewujudkan keterwakilan perempuan di parlemen yang kemudian dirumuskan dalam berbagai kerangka hukum. Namun, kebijakan afirmatif ini justru menimbulkan permasalahan dalam implementasinya. Penelitian ini menggunakan jenis penelitian kepustakaan (library research) dengan metode penelitian yuridis normatif yang menggunakan pendekatan konseptual dan peraturan perundang-undangan. Hasil dari penelitian ini adalah ketentuan mengenai keterwakilan perempuan minimal 30% dalam pencalonan anggota legislatif sudah tidak relevan lagi diterapkan di Indonesia, karena terdapat disorientasi dalam pelaksanaannya.
Development Of Nutrition Education Media Using Video About Knowledge Of Snack Selection Among Adolescents
Authors: Putri Qori' Selviana , Rakhma Luluk Ria 
Published: January 2025

Background: Adolescents aged 13-18 years experience rapid growth, leading to increased nutritional needs. This age group often seeks additional snacks outside of meal times due to heightened appetite. However, not all snacks are nutritious. Another issue is the low food safety level of snacks sold freely in school canteens and the surrounding environment, which may not meet adolescents’ nutritional needs. This study aims to develop, determine the suitability, and assess the acceptability of video-based nutrition education media about adolescent snack selection.
Method: This research utilized the Research and Development (R&D) method, encompassing analysis, design, development, implementation, and evaluation stages. The subjects included material experts, media experts, and target audience acceptability tests. The research object was video media.
Results: The media suitability test by material experts averaged 4.37, with a CVI of 1.00. Media experts rated it at 4.47 with a CVI of 0.96. The acceptability test scored an average of 4.5 with a CVI of 1.00.
Conclusion: The video media is highly suitable and highly suitable for use as an information tool to increase knowledge about snack selection among adolescents.

Keywords: Adolescents; Snacks; Video Media.
INFLUENCE OF CURRENT RATIO, DEBT TO EQUITY RATIO, NET PROFIT MARGIN AND RETURN ON INVESMENT ON PROFIT GROWTH IN FOOD & BEVERAGE COMPANIES LISTED ON THE INDONESIAN STOCK EXCHANGE
Authors: Handoyo Ugroseno Damara Prasadhana , Nurdianah Nurdianah 
Published: January 2025

Perusahaan makanan dan minuman merupakan sektor usaha yang terus mengalami pertumbuhan. Penelitian ini bertujuan untuk mengetahui apakah secara simultan Current Ratio, Debt to Equity Ratio, Net Profit Margin dan Return On Investment berpengaruh signifikan terhadap pertumbuhan laba pada perusahaan makanan dan minuman yang terdaftar di Bursa Efek Indonesia. Penelitian ini menggunakan metode penelitian kuantitatif dengan uji statistik regresi linier berganda dan menggunakan program Static Package for Social Sciences (SPSS) versi 26.0. Teknik pengambilan sampel yang digunakan dalam penelitian adalah purposive sampling dan menghasilkan 6 (enam) perusahaan Food & Beverages yang menjadi populasi penelitian di Bursa Efek Indonesia (BEI). Teknik analisis data yang digunakan adalah uji asumsi klasik, analisis regresi linier berganda dan uji hipotesis melalui uji F dan uji t. Hasil penelitian membuktikan bahwa secara simultan Current Ratio, Debt to Equity Ratio, Net Profit Margin dan Return On Investment berpengaruh signifikan terhadap Pertumbuhan Laba pada Perusahaan Food & Beverages yang terdaftar di Bursa Efek Indonesia.

Kata Kunci: Current Ratio, Debt to Equity Ratio, Net Profit Margin dan Return On Investment serta Pertumbuhan Laba.
The Polish Current of Criticism of Fascism in the Years 1918-1939. Bibliography of Sources
Authors: Kostkiewicz Janina 
Published: January 2025

The aim of the article is to show the existence of a Polish current of scientific - mainly political, but also co-occurring with philosophical, theological and pedagogical - criticism of fascism and the selection of its sources. It was not as deep and unequivocal as the criticism of Bolshevism and Nazism. For fascism maintained a semblance of conformity with Christianity in religious, moral and social terms. In addition to journalistic articles most often treating fascism as a barrier against Bolshevism, scientific analyses were published. This was done by Rev. Jan Piwowarczyk, Rev. Stefan Wyszyński, Rev. Józef Pastuszka, Rev. Henryk Weryński, Adam Romer, Adolf Kliszewicz and others.
Fascism was seen as preparing the ground - of an individual man and the entire nation - for the coming of Bolshevism. It was seen as undermining the rights of freedom and intensifying police surveillance in the state. The regimentation of freedom and the questioning of democracy were seen together with the expansion of the administration as a ruling caste.
As políticas de formação de professores na Educação de Jovens e Adultos (EJA):
Authors: De Almeida Guenther Carlos , Desire´é Ribeiro de Castro Mad' Anna , Claudio Barbosa Sebastiäo 
Published: January 2025

O presente artigo analisou os desafios e as conquistas formativas da inserção da disciplina EJA nas licenciaturas do IFG a partir do trabalho desenvolvido pelas docentes. É uma pesquisa de natureza qualitativa, fundamentada no materialismo histórico e dialético, pois buscou apreender as contradições históricas da formação inicial dos professores voltadas para a EJA. Foram entrevistadas cinco docentes, responsáveis pela disciplina de EJA, tendo como base um roteiro inicial de questões. Os dados levantados foram confrontados com as orientações sobre a formação de professores instituídas pela legislação e as formulações teóricas sobre a temática da EJA. Apreendeu-se que há um apagamento da EJA nas últimas políticas educacionais instituídas para a formação inicial do docente. Contudo, observou-se que, onde é realizada, há um grande ganho formativo, segundo as docentes.
Desain sistem informasi data produk finish good dengan pendekatan RAD
Authors: Wahyudi Pauji , Suherman  , Muhamad Fatchan  
Published: January 2025

Dalam suatu perusahaan, di perlukan adanya pemeriksaan yang kontinyu terhadap data produk finish good. Hal ini di maksudkan untuk peningkatan kualitas dan efisiensi dari produksi perusahaan. Salah satunya pada PT. Nitigura Indonesia seringkali menghadapi permasalahan pada pengelolaan data produk finish good. Dalam pengolahan data produk finish good yang dilakukan oleh bagian produksi masih memiliki beberapa kekurangan yaitu proses pencatatan laporan data produk finish good yang dilakukan oleh bagian produksi masih menggunakan metode manual dan tidak bisa melakukan penginputan laporan data produk finish good di hari yang sama karena laporan data produk finish good dicatat di lembar kerja hasil produksi menggunakan kertas sehingga membutuhkan waktu yang cukup lama, dalam penyimpanan data saat ini tidak memiliki keamanan dan organisasi yang tepat, yang menyebabkan data kurang aman dan tidak terorganisir dengan baik seperti kertas laporan produksi yang ditumpuk di atas meja, sehingga laporan data produk finish good berpotensi hilang serta tercampur dengan laporan hasil produksi lainnya. Berdasarkan masalah di atas maka penulis mengusulkan membuat aplikasi sistem informasi data produk finish good yang mudah dioperasikan dengan cepat, Metode yang digunakan dalam penelitian ini adalah Rapid Application Development (RAD) dengan tahapan perencanaan kebutuhan, desain sistem, pengembangan dan implementasi.
When group grievances become personal: The neural correlates of group and personal rejection
Authors: Marcos-Vidal Luis , Gil-Buitrago Helena , Cisma Irene , Hendricks Rosamunde C. , Atran Scott , Pretus Clara 
Published: January 2025

AbstractWitnessing rejection against one’s group can have similar impacts on psychological distress and aggression as experiencing rejection personally. In this study, we investigated the neural activity patterns of group rejection and whether they resemble those of personal-level rejection. We first identified the neural correlates of social rejection (exclusion based on negative attention) compared with ostracism (exclusion based on lack of social connection) and then compared group-level to personal-level rejection. We employed a novel social exclusion task, “RateME,” to induce group and personal rejection and Cyberball to evoke ostracism during fMRI scans. Our results showed that personal rejection increased activity in regions associated with autobiographical memory and self-identity, such as the dorsomedial prefrontal cortex and the lingual gyrus, whereas ostracism engaged areas related to social pain and salience, including the anterior cingulate cortex and the insula. Additionally, group and personal-level rejection elicited similar neural activity patterns, regardless of participants’ fusion with the rejected groups. Therefore, group membership seems sufficient for group rejection to trigger self-referential processing pathways similar to those activated by personal rejection. Our findings highlight the overlapping neural mechanisms underlying personal and group-level grievances, which may explain the detrimental effects of group rejection on aggression, extremism, and intergroup conflict.
Observed Steep and Shallow Spectra, Narrow and Broadband Spectra, Multifrequency Simultaneous Spectra, and Statistical Fringe Spectra in Fast Radio Bursts: Various Faces of Intrinsic Quasi-periodic Spectra?
Authors: Zhong Shu-Qing , Xie Wen-Jin , Gu Jia-Hong 
Published: January 2025

Abstract
Through analysis, modelings, and simulations, we show that if the spectra of fast radio bursts (FRBs) are intrinsically quasi-periodic, and likely produced by coherent curvature radiation from quasi-periodic structured bunches, then the observed steep and shallow spectra, narrow and broadband spectra, multifrequency simultaneous spectra, as well as possible statistical fringe spectra in FRBs, could all be various manifestations of them. If so, the period properties of the structured bunches, as inferred from the observed multifrequency simultaneous spectra and potential statistical fringe spectra, may provide valuable insights into the mechanisms behind the formation of such structured bunches.
An Extreme Stellar Prominence Eruption Observed by LAMOST Time-domain Spectroscopy
Authors: Lu Hong-Peng , Tian Hui , Zhang Li-Yun , Chen He-Chao , Li Ying , Yang Zi-Hao , Wang Jia-Sheng , Zhang Jia-Le , Sun Zheng 
Published: January 2025

Abstract
We report the detection of an extreme stellar prominence eruption on the M dwarf Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST) J044431.62+235627.9, observed through time-domain Hα spectroscopy with the LAMOST. This prominence eruption was accompanied by a superflare lasting over 160.4 minutes. The Hα line profile exhibits significant blue-wing enhancement during the impulsive phase and near the flare peak, with a projected bulk blueshift velocity of −228 ± 11 km s−1 and a maximum blueshift velocity reaching −605 ± 15 km s−1. Velocity analysis of the eruptive prominence at various heights above the stellar surface indicates that some of the projected ejection velocities along the line of sight exceed the corresponding escape velocities, suggesting a potential coronal mass ejection (CME). The equivalent width (EW) of the Hα blue-wing enhancement in this eruption appears to be the largest observed to date and is comparable to the EW of the Hα line profile during the quiescent phase of the host star. We performed a two-cloud modeling for the prominence and the associated flare, which suggests that the eruptive prominence has a mass ranging from 1.6 × 1019 to 7.2 × 1019 g. More importantly, the mass ratio of the erupting prominence to its host star is the largest among all reported stellar prominence eruptions/CMEs.