bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rising trends in the predicted 10-year risk of cardiovascular diseases among Royal Thai Army personnel from 2017 to 2021
Authors: Sakboonyarat Boonsub , Poovieng Jaturon , Jongcherdchootrakul Kanlaya , Srisawat Phutsapong , Hatthachote Panadda , Mungthin Mathirut , Rangsin Ram 
Published: January 2023

AbstractDeaths from cardiovascular diseases (CVD) are becoming a growing threat to global health, including in Thailand. The aim of the present study was to identify the recent trends in the predicted 10-year risk of CVD among Royal Thai Army (RTA) personnel from 2017 to 2021. The predicted 10-year risk for CVD was calculated through the use of the 2008 updated version of the risk algorithm derived from the Framingham Heart Study data. The current study included 346,355 active-duty RTA personnel aged 30–60 years. The age- and sex-adjusted mean of the predicted 10-year risk for CVD significantly increased from 10.8% (95% CI: 10.8–10.9%) in 2017 to 11.7% (95% CI: 11.6–11.7%) in 2021 (p for trend < 0.001). The overall age- and sex-adjusted prevalence of intermediate-to-high predicted 10-year risk for CVD remarkably surged from 24.9% (95% CI: 24.4–25.4%) in 2017 to 29.5% (95% CI: 29.0–30.0%) in 2021 (p for trend < 0.001). The modifiable risk factors for CVD, including high systolic blood pressure, high body mass index, and current smoking in this population, should be alleviated to mitigate the risk for CVD in the future.
Production of diamond using intense heavy ion beams at the FAIR facility and application to planetary physics
Authors: Tahir Naeem Ahmad , Bagnoud Vincent , Neumayer Paul , Piriz Antonio Roberto , Piriz Sofia Ayelen 
Published: January 2023

AbstractDiamonds are supposedly abundantly present in different objects in the Universe including meteorites, carbon-rich stars as well as carbon-rich extrasolar planets. Moreover, the prediction that in deep layers of Uranus and Neptune, methane may undergo a process of phase separation into diamond and hydrogen, has been experimentally verified. In particular, high power lasers have been used to study this problem. It is therefore important from the point of view of astrophysics and planetary physics, to further study the production processes of diamond in the laboratory. In the present paper, we present numerical simulations of implosion of a solid carbon sample using an intense uranium beam that is to be delivered by the heavy ion synchrotron, SIS100, that is under construction at the Facility for Antiprotons and Ion Research (FAIR), at Darmstadt. These calculations show that using our proposed experimental scheme, one can generate the extreme pressure and temperature conditions, necessary to produce diamonds of mm3 dimensions.
Oceanic SACZ produces an abnormally wet 2021/2022 rainy season in South America
Authors: Pezzi Luciano P. , Quadro Mario F. L. , Souza Everaldo B. , Miller Arthur J. , Rao Vadlamudi B. , Rosa Eliana B. , Santini Marcelo F. , Bender Andréia , Souza Ronald B. , Cabrera Mylene J. , Parise Claudia K. , Carvalho Jonas T. , Lima Luciana S. , de Quadros Maria Rita L. , Nehme Douglas M. , António Jaime F. 
Published: January 2023

AbstractThe oceanic South Atlantic Convergence Zone (SACZ) has played a major role during South America’s 2021/2022 summer extreme rainy season, being responsible for more than 90% of the precipitation in some regions of Southeast Brazil and in some regions of the Southwestern Atlantic Ocean (SWA). The summer of 2021/2022 was unique and rare and considered an abnormally humid season as verified by official Brazilian Institutes. First, the unusual number of cases of SACZ episodes (seven), was the highest recorded in the last decade. Second, all the cases that occurred were oceanic SACZ that assumed characteristics of an Atmospheric River and produced an excessively anomalous amount of precipitation during this period. Excess precipitation along with the regions located in mountainous and very uneven relief, which by orographic effects favors high precipitation volumes, were responsible for amplifying the observed impacts, such as landslides and floods that caused several losses to society. We also showed the main effects of coupling and interaction between the waters of the surface layer of the SWA and the atmosphere. Our learning from this study ends with the unprecedented results of how the marine atmospheric boundary layer (MABL) is locally modulated by the sea surface temperature (SST) that lies just below it. Until the present moment, we emphasize that this important mechanism has not been widely highlighted in the literature, showing that even though the ocean is colder than before oceanic SACZ is established, it is still warmer than the overlying air, thus, the ocean continues to be an active source of heat and moisture for the atmosphere and enhances the MABL instability process.
Adaptive resistance to lorlatinib via EGFR signaling in ALK-rearranged lung cancer
Authors: Katayama Yuki , Yamada Tadaaki , Tanimura Keiko , Tokuda Shinsaku , Morimoto Kenji , Hirai Soichi , Matsui Yohei , Nakamura Ryota , Ishida Masaki , Kawachi Hayato , Yoneda Kazue , Hosoya Kazutaka , Tsuji Takahiro , Ozasa Hiroaki , Yoshimura Akihiro , Iwasaku Masahiro , Kim Young Hak , Horinaka Mano , Sakai Toshiyuki , Utsumi Takahiro , Shiotsu Shinsuke , Takeda Takayuki , Katayama Ryohei , Takayama Koichi 
Published: January 2023

AbstractAnaplastic lymphoma kinase (ALK)-tyrosine kinase inhibitors rarely elicit complete responses in patients with advanced ALK-rearranged non-small cell lung cancer (NSCLC), as a small population of tumor cells survives due to adaptive resistance. Therefore, we focused on the mechanisms underlying adaptive resistance to lorlatinib and therapeutic strategies required to overcome them. We found that epidermal growth factor receptor (EGFR) signaling was involved in the adaptive resistance to lorlatinib in ALK-rearranged NSCLC, activation of which was induced by heparin-binding EGF-like growth factor production via c-Jun activation. EGFR inhibition halted ALK-rearranged lung cancer cell proliferation by enhancing ALK inhibition-induced apoptosis via suppression of Bcl-xL. Xenograft models showed that the combination of EGFR inhibitor and lorlatinib considerably suppressed tumor regrowth following cessation of these treatments. This study provides new insights regarding tumor evolution due to EGFR signaling after lorlatinib treatment and the development of combined therapeutic strategies for ALK-rearranged lung cancer.
Vertrauen ist gut – Kontrolle ist besser
Authors: Comploj Evi , Ferro Federica , D'Elia Carolina , Trenti Emanuela , Palermo Salvatore , Pycha Armin 
Published: January 2023

ZusammenfassungWir berichten über den Fall einer 39-jährigen Patientin, die unter dem Verdacht eines Nebennierenadenoms hospitalisiert und operiert werden sollte und schlussendlich die seltene Diagnose eines Magendivertikels der Magenhinterwand erhielt.
Telemedizinische Unterstützung der feto-neonatalen Versorgung
in einer Region – Teil II: Strukturelle Voraussetzungen und
Anwendungsbereiche in der Neonatologie
Authors: Eckart Falk , Kaufmann Maxi , Rüdiger Mario , Birdir Cahit , Mense Lars 
Published: January 2023

ZusammenfassungTelemedizinische Infrastruktur zur Patientenbeurteilung, -versorgung und
-nachbetreuung sowie dem interdisziplinären Austausch kann dazu
beitragen, auch außerhalb von spezialisierten Zentren eine wohnortnahe,
höchsten Qualitätsansprüchen genügende
Patientenversorgung sicherzustellen. In der Neonatologie wird die
einrichtungsübergreifende, synchrone audio-visuelle Kommunikation
insbesondere im anglo-amerikanischen Raum bereits seit vielen Jahren angewandt.
Anwendungsgebiete umfassen dabei die Gebiete der erweiterten neonatalen
Erstversorgung und Reanimation, spezifischer diagnostischer Anwendungen, z.B.
des ROP-Screenings und der Echokardiografie sowie der elterlichen Betreuung,
regelmäßiger telemedizinischer Visiten und der fachlichen
Weiterbildung medizinischen Personals, insbesondere unter Nutzung von
Simulationstrainings. Für die Implementierung solcher telemedizinischen
Infrastrukturen müssen bestimmte organisatorische, medizinrechtliche und
technische Anforderungen an Hardware, Software und Struktur- bzw.
Prozessorganisation, erfüllt sein. Die konkrete Umsetzung einer aktuell
in Implementierung befindlichen telemedizinischen Infrastruktur für die
Region Ostsachsen wird hier am Beispiel des Zentrum für
Feto/Neonatale Gesundheit (SCFNH) demonstriert. Im Rahmen feto-neontaler
Kompetenzverbünde wie dem SCFNH kann mittels einer
flächendeckend, gut strukturierten und etablierten telemedizinischen
Infrastruktur die medizinische Versorgungsqualität, Patientensicherheit
und -zufriedenheit in einer Region erhöht werden.
Synthesis of 1-Thiaphenalene Derivatives via Radical Cyclization of 1-Naphthalenesulfonyl Chlorides with Alkynes
Authors: Wei Youhao , Liu Jige , Zhu Chen , Wu Xinxin , Chen Yasu 
Published: January 2023

AbstractFunctionalized thiaphenalene derivatives are of high synthetic value, yet their preparation remains underexplored. Herein, we report an efficient approach for the synthesis of 1-thiaphenalene derivatives through radical cyclization of 1-naphthalenesulfonyl chlorides with alkynes. A variety of 1-thiaphenalene derivatives are readily furnished that are otherwise difficult to prepare by present methods. The protocol features mild photocatalytic conditions, broad functional-group compatibility, and high product diversity.
Recent Advances in Electro- or Photochemical Driven Transformations via Cleavage of the C–N Bond of Quaternary Ammonium Salts
Authors: Kong Xianqiang , Cao Zhong-Yan , Chen Xiaohui , Wang Neng-Zhong , Cheng Ya-Min 
Published: January 2023

AbstractSelective functionalization via cleavage of the C–N bond of amines has proven to be challenging partly because of its relatively high bond dissociation energy, even though amines are abundant and readily available. To meet this challenge, many new transformations based on the pre-activation of the C–N bond before the cleavage have been developed. Among them, the conversion of amines into quaternary ammonium salts has certain advantages, such as easy preparation from primary, secondary, or tertiary amines, as well as stable storage and usage. Although transition metal catalysis has been frequently applied for developing new transformations via oxidative addition of the C–N bond of quaternary ammonium salts, recent studies have shown a new dimension by using green electro- or photochemical tools. In this short review, recent advances in electro-, photo-, or photoelectrochemical driven synthetic applications of quaternary ammonium salts have been summarized and discussed.1	Introduction2	Electrochemical Driven Transformations3	Photochemical Driven Transformations4	Photoelectrochemical Driven Transformations5	Conclusion and Outlook
Non-Symmetric Bispyrrolotetrathiafulvalene Building Blocks
Authors: Jeppesen Jan O. , Neumann Mathias S. 
Published: January 2023

AbstractThe use of redox-responsive compounds has received a lot of research attention in the field of molecular nanotechnology. Tetrathiafulvalene (TTF) is one of the key redox units that has been used to construct redox-active materials. A wide variety of TTF derivatives have been reported including the monopyrroloTTF (MPTTF) and the bispyrroloTTF (BPTTF) derivatives. However, the use of BPTTF as a building block is still limited, despite several favorable properties of its highly π-extended structure. Herein, the synthesis and functionalization of two novel non-symmetric BPTTF building blocks are reported. The key intermediates in these new synthetic protocols are 4,6-dimethyl-5-tosyl-5H-[1,3]dithiolo[4,5-c]pyrrole-2-thione and 5-(4-iodophenyl)-4,6-dimethyl[1,3]dithiolo[4,5-c]pyrrole-2-thione, which can be obtained in moderate to high yields in a two- or three-step synthetic procedure from 2,5-dimethyl-3,4-dithiocyanato-1-tosyl-1H-pyrrole and 1-(4-iodo­phenyl)-2,5-dimethyl-1H-pyrrole, respectively.
Recent Advances in the Trifluoromethylation Reactions of Isonitriles To Construct CF3-Substituted N-Heterocycles
Authors: Kiss Loránd , Aradi Klára 
Published: January 2023

AbstractDue to the increasing need for fluorine-containing drugs, the synthesis of organofluorine scaffolds has become a highly researched area of synthetic organic chemistry. The introduction of the trifluoromethyl group into the structure of an organic molecule has considerable potential and several advantages concerning the characteristics of the fluorinated pharmaceuticals. The incorporation of a CF3 group at multiple bonds containing a nitrogen heteroatom is a relatively new field and currently it is an expanding area of synthetic chemistry. This short review summarizes, for the first time, recent developments in trifluoromethylation reactions of isonitriles.1	Introduction2	Trifluoromethylation Reactions of Isonitriles2.1	Synthesis of Trifluoromethylated Phenanthridine Derivatives2.2	Synthesis of Trifluoromethylated Quinoline Derivatives2.3	Synthesis of Trifluoromethylated Isoquinoline Derivatives2.4	Synthesis of Trifluoromethylated Indole Derivatives2.5	Synthesis of Trifluoromethylated Pyridine Derivatives3	Summary and Outlook
Report on the AFRIMETS.M.T-S1 supplementary torque comparison for 500 N·m and 1000 N·m between NIS (Egypt) and PTB (Germany)
Authors: Khaled K M , Brüge Andreas , Kumme Rolf 
Published: January 2023

Main text
The AFRIMETS.M.T-S1 supplementary comparison has been conducted between NIS (Egypt) and PTB (Germany) at the torque of 500 N·m and 1000 N·m in both clockwise and anticlockwise directions. The comparison results revealed the equivalence of torque realized by the 1000 N·m DWTSMs of NIS and of PTB within their measurement uncertainties.
To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database https://www.bipm.org/kcdb/.
The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
High-performance transparent electromagnetic interference shielding film based on metal meshes
Authors: Chung Sung-il , Kim Pan Kyeom , Ha Tae-gyu 
Published: January 2023

Abstract
Transparent electromagnetic interference (EMI) shielding films have gained considerable attention for the commercialization of the 5G wireless technology based on electromagnetic waves in the GHz range. In this study, transparent EMI shielding films with embedded metal meshes on a 100 μm thick polyethylene terephthalate film for EMI shielding were fabricated using ultraviolet imprinting and Ag paste filling techniques. The various EMI shielding film types were fabricated by varying the width, aperture size, and height of the mesh electrode to evaluate the efficiency of the EMI shielding according to the incident electromagnetic wave frequency and morphology of the mesh metallic electrodes. The results indicate that the EMI shielding efficiency (SE) increased with a decrease in the aperture size of the metal mesh electrodes and an increase in their height. The average EMI SE values of the fabricated film in the 0.5–18 GHz range reached 48.3 dB and 59.6 dB at a light transmittance of approximately 90% and 77%, respectively. The fabricated EMI shielding films can be used for various applications, such as communications, aerospace, medical equipment, and military.
Homodyne nonclassical area as a nonclassicality indicator
Authors: Rohith M , Kannan S , Sudheesh C 
Published: January 2023

Abstract
We propose a legitimate and easily computable nonclassicality indicator for the states of the electromagnetic field based on the standard deviation in the measurement of the homodyne rotated quadrature operator. The proposed nonclassicality indicator is the nonclassical area projected by the optical tomogram of the quantum state of light on the optical tomographic plane. If the nonclassical area projected by the optical tomogram of a quantum state is greater than zero, the state is nonclassical, and the area is zero for the pure classical state. It is also noted that the nonclassical area of a quantum state increases with an increase in the strength of nonclassicality-inducing operations on the state, such as squeezing, photon addition, etc. We have tested the validity of the nonclassical area measure by calculating the same for certain well-known nonclassical states, and found that essential features of the nonclassicality shown by the states are captured in the nonclassical area. We also show that the nonclassical area is robust against environment-induced decoherence of the states. The nonclassical area projected by the optical tomogram of a quantum state of light is experimentally tractable using the balanced homodyne detection of the quadrature operator of the field, avoiding the reconstruction of the density matrix or the quasiprobability distribution of the state.
N2O5 in air discharge plasma: energy-efficient production, maintenance factors and sterilization effects
Authors: Wang Zifeng , Zhu Mengying , Liu Dingxin , Liu Linbo , Wang Xiangyu , Chen Jinkun , Guo Li , Liu Yunen , Hou Mingxiao , Rong Mingzhe 
Published: January 2023

Abstract
N2O5, a reactive species produced by air discharge plasma, has recently attracted much attention. Due to its high reactivity and solubility, N2O5 is a key molecule in nitrogen fixation processes and exhibits promising prospects in plasma biomedicine. However, thus far, it is not well known how to produce N2O5 efficiently and then maintain its concentration under the action of fast removal reactions. In view of this, N2O5 production by dielectric barrier discharge (DBD) alone and by the combination of DBD and gliding arc discharge is compared in this paper. It is found that the combination method can yield over three times the concentration of N2O5 compared to the single DBD method with the optimum discharge power. Moreover, the concentration of N2O5 in the effluent gas can be maintained once O3 also exists because O3 can continually produce N2O5 to compensate for its reduction. Finally, the sterilization effects of both the plasma effluent gas and plasma-activated water have trends similar to the trend of the gaseous N2O5 concentration, implying that N2O5 plays an important role in sterilization. This paper enhances the understanding of N2O5 chemistry in air discharge plasma and provides an effective way to produce and maintain N2O5 for subsequent applications.
Performance improvement of Hf0.45Zr0.55O
x
ferroelectric field effect transistor memory with ultrathin Al–O bonds-modified InO
x
channels
Authors: Meng Wei , Xiao Dong-Qi , Luo Bin-Bin , Wu Xiaohan , Zhu Bao , Liu Wen-Jun , Ding Shi-Jin 
Published: January 2023

Abstract
Ferroelectric field effect transistor (FeFET) memories with hafnium zirconium oxide (HZO) ferroelectric gate dielectric and ultrathin InO
x
channel exhibit promising applicability in monolithic three-dimensional (M3D) integrated chips. However, the inferior stability of the devices severely limits their applications. In this work, we studied the effect of single cycle of atomic-layer-deposited Al–O bonds repeatedly embedded into an ultrathin InO
x
channel (∼2.8 nm) on the Hf0.45Zr0.55O
x
FeFET memory performance. Compared to the pure InO
x
channel, three cycles of Al–O bonds modified InO
x
channel (IAO-3) generates a much larger memory window (i.e. drain current ratio between the programmed and erased devices) under the same program conditions (+5.5 V/500 ns), especially after post-annealing at 325 °C for 180 s in O2 (1238 versus 317). Meanwhile, the annealed IAO-3 FeFET memory also shows quite stable data retention up to 104 s, and much more robust program/erase stabilities till 105 cycles. This is because the modification of strong Al–O bonds stabilizes the oxygen vacancies and reduces the bulk trap density in the channel. Furthermore, it is indicated that the program and erase efficiencies increase gradually with reducing the channel length of the memory device. By demonstrating markedly improved performance of the HZO FeFET memory with the ultrathin IAO-3 channel, this work provides a promising device for M3D integratable logic and memory convergent systems.
Shell effects and free-electrons in electromigrated oxidized Cu-nanocontacts
Authors: Hauser Julia , Rothhardt Daniel , Pfender-Siedle Robert , Hoffmann-Vogel Regina 
Published: January 2023

Abstract
Electromigration in interconnects continues to be an important field of study in integrated circuits as the interconnects are planned to shrink in size at comparable pace as the semiconductor functional elements. Through shrinking the interconnects approach the regime where quantum size effects become important. The observation of quantum size and shell effects is usually restricted either to low-temperatures or vacuum conditions or to chemically inert materials such as Au. Here, we show that in electromigrated Cu nanocontacts such effects can be observed at room temperature and room pressure even in the presence of oxidation. Our data provide evidence that the nanocontacts are nearly spherical objects with a triangular-cylindrical symmetry of their electronic wave functions with a stronger free-electron-like character compared to previous results. We do not observe a detrimental effect of oxygen. The presence of shell effects has implications for the technological use of Cu nanocontacts as interconnects in integrated circuits and could lead to the use of electronic wave functions of shells in such interconnects.
Acoustic Doppler effect experiment: integration of frequency sound generator, tracker and visual analyser
Authors: Sam Hun Hanisah , Che Abu Bakar Siti Norulakmal , Mat Daud Anis Nazihah 
Published: January 2023

Abstract
This study was conducted to design an acoustic Doppler effect experimental setup by integrating the frequency sound generator application, tracker and visual analyser. The experimental setup was evaluated by determining the frequency of the sound source in four cases; (a) a stationary observer and a moving sound source, (b) a stationary sound source and a moving observer, (c) a sound source and an observer are moving in the same direction and (d) a sound source and an observer are moving in the opposite direction. The findings showed that the percentage errors for the calculated values of the sound source frequency were less than 0.40% compared to the reference values for all four cases. Hence, the proposed acoustic Doppler effect experimental setup can be used to improve the acoustic Doppler effect concept among students.
A thermo-viscoelastic constitutive model addressing the cyclic shape memory effect for thermo-induced shape memory polymers
Authors: Li Jian , Liang Zhihong , Liu Junjie , Yu Chao , Zhang Xuelian , Kan Qianhua 
Published: January 2023

Abstract
The cyclic shape memory effect of thermo-induced shape memory polymers (TSMPs) is a typical thermo-mechanical process that can be affected by thermo-mechanical loading histories. During the deformation stage of the cyclic shape memory effect, polymer chains exhibit the initial dissociation of sub-entanglements, slipping and orientation with the increase in the deformation. The strain can be recovered with the internal rotation of the dihedral angle due to the enhancing motion of polymer chains during the reheating. Based on the rheological theory, a thermo-viscoelastic model is proposed to capture the cyclic shape memory effect of TSMPs. A temperature-dependent stress threshold value is introduced to reflect the slipping of polymer chains. In order to take into account how orientation affects the cyclic shape memory effect, a relationship between the strain and orientation is constructed and introduced into the evolution equations of elastic modulus, viscosity and irrecoverable strain. By comparing the experimental and simulated results at different loading levels and numbers of cycles, the proposed model is verified. The results show that the proposed model can reasonably predict the cyclic shape memory effect of TSMPs.