bluuebunny/crossref_metadata_2025_split huggingface dataset:
Aortocoronary dissection during percutaneous coronary interventions for chronic total occlusion: Insights from the PROGRESS‐CTO registry
Authors: Kostantinis Spyridon , Rempakos Athanasios , Simsek Bahadir , Karacsonyi Judit , Allana Salman S. , Alaswad Khaldoon , Basir Mir Babar , Krestyaninov Oleg , Khelimskii Dmitrii , Gorgulu Sevket , Davies Rhian E. , Benton Stewart M. , Khatri Jaikirshan J. , Poommipanit Paul , Choi James W. , Jaber Wissam A. , Rinfret Stephane , Nicholson William , Aygul Nazif , Altunkeser Bulent Behlul , ElGuindy Ahmed M. , Abi Rafeh Nidal , Goktekin Omer , Mastrodemos Olga C. , Rangan Bavana V. , Sandoval Yader , Burke M. Nicholas , Brilakis Emmanouil S. 
Published: May 2023

AbstractBackgroundAortocoronary dissection is a potentially serious complication of chronic total occlusion (CTO) percutaneous coronary intervention (PCI).MethodsWe examined the incidence, mechanisms, treatment, and outcomes of aortocoronary dissection among 12,117 CTO PCIs performed between 2012 and 2022 in a large multicenter CTO PCI registry.ResultsThe incidence of aortocoronary dissection was 0.2% (n = 27). Most aortocoronary dissections occurred in the right coronary artery (96.3%, n = 26). The baseline clinical characteristics of patients with and without aortocoronary dissection were similar, except for dyslipidemia, which was less common in patients with aortocoronary dissection (70.4% vs. 86.0%; p = 0.019). The retrograde approach was used more commonly among cases complicated by aortocoronary dissection (59.3% vs. 31.0%; p = 0.002). Technical (74.1% vs. 86.6%; p = 0.049) and procedural (70.4% vs. 85.2%; p = 0.031) success rates were lower among aortocoronary dissection cases, with a similar incidence of in‐hospital major adverse cardiovascular events (3.7% vs. 2.0%; p = 0.541). Of the 27 patients with aortocoronary dissection, 19 (70.4%) were treated with ostial stenting and 8 (29.6%) were treated conservatively without subsequent adverse clinical outcomes. No patients required emergency surgery. Follow‐up was available for 22 patients (81.5%): during a mean follow up of 767 (±562) days, the incidence of in‐stent restenosis was 11.1% (n = 3).ConclusionsAortocoronary dissection occurred in 0.2% of CTO PCIs performed by experienced operators, was associated with lower technical and procedural success, and was treated most commonly with ostial stenting. None of the patients required emergency cardiac surgery.
Quantitative flow ratio modulated by intracoronary optical coherence tomography for predicting physiological efficacy of percutaneous coronary intervention
Authors: Ding Daixin , Tu Shengxian , Li Yingguang , Li Chunming , Yu Wei , Liu Xun , Leone Antonio Maria , Aurigemma Cristina , Romagnoli Enrico , Vergallo Rocco , Trani Carlo , Wijns William , Burzotta Francesco 
Published: May 2023

AbstractBackgroundThe combination of coronary imaging assessment and blood flow perturbation estimation has the potential to improve percutaneous coronary intervention (PCI) guidance.ObjectivesWe aimed to evaluate a novel method for fast computation of Murray law‐based quantitative flow ratio (μQFR) from coregistered optical coherence tomography (OCT) and angiography (OCT‐modulated μQFR, OCT‐μQFR) in predicting physiological efficacy of PCI.MethodsPatients treated by OCT‐guided PCI in the OCT‐arm of the Fractional Flow Reserve versus Optical Coherence Tomography to Guide RevasculariZAtion of Intermediate Coronary Stenoses trial (FORZA, NCT01824030) were included. Based on angiography and OCT before PCI, simulated residual OCT‐μQFR was computed by assuming full stent expansion to the intended‐to‐treat segment. Plaque composition was automatically characterized using a validated artificial intelligence algorithm. Actual post‐PCI OCT‐μQFR pullback was computed based on coregistration of angiography and OCT acquired immediately after PCI. Suboptimal functional stenting result was defined as OCT‐μQFR ≤ 0.90.ResultsPaired simulated residual OCT‐μQFR and actual post‐PCI OCT‐μQFR were obtained in 76 vessels from 74 patients. Simulated residual OCT‐μQFR showed good correlation (r = 0.80, p < 0.001), agreement (mean difference = −0.02 ± 0.02, p < 0.001), and diagnostic concordance (79%, 95% confidence interval: 70%–88%) with actual post‐PCI OCT‐μQFR. Actual post‐PCI in‐stent OCT‐μQFR had a median value of 0.02 and was associated with left anterior descending artery lesion location (β = 0.38, p < 0.001), higher baseline total plaque burden (β = 0.25, p = 0.031), and fibrous plaque volume (β = 0.24, p = 0.026).ConclusionsThis study based on patients enrolled in a prospective OCT‐guidance PCI trial shows that simulated residual OCT‐μQFR had good correlation, agreement, and diagnostic concordance with actual post‐PCI OCT‐μQFR. In OCT‐guided procedures, OCT‐μQFR in‐stent pressure drop was low and was significantly predicted by pre‐PCI vessel/plaque characteristics.
Behavior of Constitutional Dynamic Networks: Competition, Selection, Self‐sorting in Cryptate Systems
Authors: Osypenko Artem , Cabot Rafel , Armao Joseph J. , Kovaříček Petr , Santoro Antonio , Lehn Jean‐Marie 
Published: May 2023

AbstractUnderstanding dynamic systems is a crucial step toward the design of complex matter. Here, we aim to study the behavior of Constitutional Dynamic Networks (CDNs) in conditions of dynamic competition, taking cryptands and metal cations as a test bed. The CDNs of cryptates were analyzed by NMR spectroscopy. The experimental results were complemented by extensive numerical simulations, based on a large amount of thermodynamic and kinetic data available in the literature for cryptates. Although the CDN′s output is a result of the interplay between the individual stability constants of the complexes in a mixture, the overall effect may be governed by only one – the most thermodynamically stable member of a network. Significantly, these findings indicate that an increase in complexity (multiplicity and connectivity) of a system may, in conditions of dynamic competition, result in “simplexity”, i. e. a simplification of the output of the system.
Pillar[5]arene‐Based AIE Supramolecular Polymer Networks Exhibiting Various Fluorescence to Achieve Visible Surveillance
Authors: Sheng Lan , Liu Hui , Hu Ziqing , Ji Xiaofan 
Published: May 2023

AbstractSupramolecular polymer networks (SPNs) based on pillar[n]arene are widely studied and it is known that evolution from linear polymers to SPNs occurs as a progressive process, which is of importance to monitor the detailed morphology throughout the process. Yet, the current reports related to that distinction by employing fluorescence approach have realized confined success, it still remains a challenge to distinguish the various states visually. Herein, a fluorescent group of the pyrene benzohydrazonate‐based (PBHZ‐based) derivative is introduced into the pillar[5]arene based SPNs gained from host–guest recognition, enabling the visual monitoring during the formation of SPNs. The whole visual detection was based on the fluorescence color transition ranging from blue to green relying on the gradual aggregated PBHZ molecules upon the increasing cross‐linking degree. Besides, the stimuli‐responsiveness of this SPNs was confirmed that increasing the temperature or adding a reducing agent would reduce the cross‐linking degree.
Isoform‐Selective Fluorescent Labeling of 14‐3‐3σ by Acrylamide‐Containing Fusicoccins
Authors: Tanaka Kenta , Hatano Yoshiya , Ohkanda Junko 
Published: May 2023

AbstractThe 14‐3‐3 family of proteins is central to the regulation of signaling pathways driven by serine/threonine kinases. In humans, 14‐3‐3 consists of seven highly conserved isoforms, yet the function of each isoform remains to be fully elucidated. Synthetic agents capable of isoform‐specific fluorescent labeling of 14‐3‐3 would provide a useful tool for studying in depth the biological roles of isoforms. In this study, the 14‐3‐3σ isoform was evaluated, which possesses a unique Cys38, and a natural product‐based fluorescent labeling agent was designed by introducing an acrylamide group and a fluorescent dye to fusicoccin (FC). In vitro evaluation demonstrated that 12‐hydroxy 1 and 2 exhibit 14‐3‐3σ selective labeling activity over 14‐3‐3ζ in the presence of a mode‐3 phospholigand. Furthermore, 2 was shown to label 14‐3‐3σ in cell lysate in the presence of a C‐terminal mode‐3 phosphopeptide derived from ERα, with no apparent nonspecific labeling. These results indicate that 2 is capable of selective fluorescent detection of 14‐3‐3σ upon binding to mode‐3 phospholigand under biologically relevant conditions.
Efficient resource allocation algorithms for multihop D2D approach in 5G network
Authors: Chauhan Srishti , Gupta Amol , T Velmurugan , S Nandakumar 
Published: May 2023

SummaryNow the 5G network systems are expected to enhance their throughput. Device‐to‐device (D2D) communication is one such technique that offers an effective solution. The existing cellular user (CU) communication must be ensured that this solution had minimized its interference with it. Hence, designing methods for resource allocation for D2D transmission is also important. Such allocation will maximize network throughput without causing much interference with the present communication. Apart from these, it ensures delay minimization and achieves fairness among user data rates. But when distance is increased, an extension from direct D2D communication (single‐hop) to multi‐hop is necessary. At the same time, its objectives shall be retained. In the proposed work, initially, a comparative study is done on different algorithms for multi‐hop (two‐hop) D2D communication pairs. While studying different algorithms such as random allocation (RA), graph allocation (GA), particle swamp optimization (PSO), and technique for order preference by similarity to the ideal solution (TOPSIS), they are also analyzed, looking for the possibility of a particular combination of them to achieve specific objectives. The realized method has improved performance even in the situation of an increase in distance. The arrived two methods also support a better data rate. The first method allocates resources based on orthogonal sharing. The second method is for allocating resources to them that have cellular orientation. The simulated results exhibit the improved capability of the proposed methods. The method based on the graph to allocate the mentioned resources functions better. Finally, for throughput and data rates, PSO and TOPSIS techniques are implemented.
Early diagnostic value of high‐sensitivity cardiac troponin T for cancer treatment‐related cardiac dysfunction: a meta‐analysis
Authors: Lv Xinfang , Pan ChenLiang , Guo Huan , Chang Juan , Gao Xiang , Wu Xue , Zhi Xiaodong , Ren Chunzhen , Chen Qilin , Jiang Hugang , Zhao Xinke , Liu Kai , Li Yingdong 
Published: May 2023

AbstractEarly diagnosis of cancer treatment‐related cardiac dysfunction (CTRCD) is important as cancer therapy increases the risk of cardiac dysfunction. High‐sensitivity cardiac troponin T (hs‐cTnT) is a highly specific marker of myocardial injury. However, its diagnostic value for CTRCD has not been systematically evaluated. This meta‐analysis aimed to evaluate whether hs‐cTnT could be used as an early diagnostic biomarker for CTRCD. We systematically surveyed PubMed, Embase, Cochrane Library, and Web of Science databases for studies of hs‐cTnT for the diagnosis of CTRCD before 1 April 2022. Patients of all ages and all cancer types who underwent echocardiographic left ventricular ejection fraction assessment and blood hs‐cTnT and received anticancer therapy (including chemotherapy, radiotherapy, targeted therapy, immune checkpoint inhibitors, and other treatments) were included in this study, resulting in a total of eight studies with 1294 patients. The occurrence of CTRCD was associated with elevated hs‐cTnT [sensitivity: 0.78, 95% confidence interval (CI): 0.64–0.88; specificity: 0.75, 95% CI: 0.59–0.86; area under the curve (AUC): 0.83, 95% CI: 0.80–0.86]. We further performed subgroup analysis and found that the AUC of hs‐cTnT elevation for the diagnosis of CTRCD increased from 0.83 to 0.90 (95% CI: 0.87–0.92) at 3–6 months, suggesting a higher early diagnostic value of hs‐cTnT compared with echocardiography for CTRCD. In terms of clinical applicability, the Fagan plot showed pre‐test and post‐test probabilities of 51% and 9%, respectively, indicating that hs‐cTnT testing can improve the accuracy of clinical diagnosis of CTRCD. However, it was not possible to determine the optimal cut‐off value for early diagnosis of CTRCD with hs‐cTnT. The Deeks funnel plot was largely symmetrical (P = 0.74); hence, publication bias was not observed. Hs‐cTnT allowed early CTRCD diagnosis at 3–6 months. However, further high‐quality research is needed to determine the optimal cut‐off value for early CTRCD diagnosis with this biomarker.
Adsorption Behavior of U(VI) and Re(VII) on Iron Sulfide Nanoparticles Modified with Titanate Nanotubes: Mechanism and Performance Insights
Authors: Pan Yixin , Zhang Pengkun , Huang Rui , Kou Jisheng 
Published: May 2023

AbstractA novel nanocomposite (TNTs‐FeS) was developed by anchoring ferrous sulfide (FeS) nanoparticles immobilized on titanate nanotubes (TNTs) by hydrothermal method to remove U(VI) and Re(VII) from aqueous solution, and the removal mechanism and efficiency were examined. The experimental results showed that the TNTs can effectively improve the dispersibility and stability of FeS. The environmental conditions, including initial solution pH, initial concentration, equilibrium time, and dosage, played an important role in the remediation process, which can affect the immobilization efficiency significantly. The maximum quantity removal of U(VI) and Re(VII) was 291.67 and 226.23 mg/g at pH of 6.0 and 12.0. The adsorption kinetics and the equilibrium isotherms of U(VI) and Re(VII) all fitted well with the pseudo‐second‐order model (R2>0.99) and the Freundlich model (R2>0.99). The main mechanism of removal by TNTs‐FeS was electrostatic attraction, chemical reduction, and surface complexation. Thus, TNTs‐FeS composites exhibited a high potential to remove U(VI) and Re(VII) heavy metal ions from the surface and groundwater.
Optimization of Mn‐Mg‐Al Mixed Oxides Composition on their Activity towards the Total Oxidation of Aromatic and Oxygenated VOCs
Authors: El Khawaja Rebecca , Rochard Guillaume , Genty Eric , Poupin Christophe , Siffert Stéphane , Cousin Renaud 
Published: May 2023

AbstractA series of mixed oxides (Mn‐Mg‐Al) is prepared by coprecipitation via a hydrotalcite route with different manganese ratios. Structural, textural, and redox properties are studied by XRD, N2‐sorption, H2‐TPR, and XPS techniques. MnxMg6‐xAl2‐O mixed oxides (with 0≤x≤6) are tested in the total oxidation of ethanol and toluene, two probe molecules representing respectively oxygenated and aromatic VOCs. Catalysts with higher manganese contents have shown the best catalytic performance for the oxidation of both ethanol and toluene. The surface activity of the materials is mainly related to the presence of manganese species in three different oxidation states (+II, +III, and +IV) in the bulk and on the material's surface. Since high Mn‐content catalysts showed similar physicochemical properties and catalytic activity, Mn4Mg2‐O is selected as the optimal composition of these materials. Furthermore, its aging test is compared to that of noble metal‐based commercial catalysts (Pd/γ‐Al2O3).
Differential electrochemical behaviour of phytofabricated and chemically synthesized silver nanoparticles towards hydrogen peroxide sensing**
Authors: Mahato Kuldeep , Baranwal Anupriya , Kumari Rohini , Srivastava Ananya , Pratap Azad Uday , Chandra Pranjal 
Published: May 2023

AbstractSilver nanoparticles (AgNPs) are one of the most widely used nanomaterials for biomedical applications. However, the impact of its synthesis by chemical and plant‐mediated routes on its differential electrochemical behaviour has not been examined till date. Here, we report for the first time the differential study of the electrochemical behaviour of the AgNPs synthesized by different routes. First, the AgNPs were obtained by different routes (chemical and phytofabrication) and extensively characterized to compare their physical properties. Thereafter, a comparison of electron transfer kinetics between chemically synthesized (Ag−C) and phyto‐fabricated (Ag‐Phy) nanoparticles (NPs) has been studied by electrochemical techniques such as potentiodynamic cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). To further investigate the electrocatalytic properties of both types of AgNPs, we have used the peroxide moieties (H2O2), and the Ag−C NPs‐based sensor probe has been reported to have four times better sensitivity than the Ag−Phy NPs‐based sensor. The AgNPs modified sensor probes have also been tested in real‐world environments to explore the consistency of their performance in complex matrices by using clinical urine samples, where we found comparable sensitivity to the standard conditions.
Diffusion kinetics of CuCo2O4 nanorods for next‐generation solid state sodium‐ion hybrid supercapacitor
Authors: Jhankal Deependra , Khan Mohammad Saquib , Yadav Bhanu , Shakya Preeti , Bhardwaj Nikita , Jhankal K. K. , Sachdev K. 
Published: May 2023

AbstractIn the current study, we report a straightforward and affordable sol‐gel preparation approach for the fabrication of spinel CuCo2O4 nanorods for sodium ion‐based hybrid supercapacitor. The morphological and structural analysis shows that appropriate purity nanorods of CuCo2O4 are formed with good stoichiometry. The electrochemical study of CuCo2O4 nanorods reveals that the electrode has highest specific capacitance of 367 F g−1 at 1 A g−1 in 1 M Na2SO4 electrolyte. Evaluation of the diffusion kinetics of sodium ions through detailed electrochemical evaluations of cyclic voltammogram (CV) showing the charge storage kinetics of CuCo2O4 is primarily performed through the diffusive limited mechanisms, suggesting the battery‐like behavior of CuCo2O4 electrode. Hybrid supercapacitor (HSC) device is fabricated by utilizing CuCo2O4 for positive and reduced graphene oxide (rGO) for negative electrodes material. The polymer gel electrolyte is used in the form of hydrogel membrane made of PVA and Na2SO4, and the HSC device (rGO || CuCo2O4) exhibits energy density of 9.18 Wh kg−1. Therefore, sodium‐ion hybrid supercapacitor electrode materials for this investigation are established using a comprehensive electrochemical kinetics.
Dose and time–response effect of photobiomodulation therapy on glycemic control in type 2 diabetic patients combined or not with hypoglycemic medicine: A randomized, crossover, double‐blind, sham‐controlled trial
Authors: Scontri Clara Maria Cobra Branco , de Castro Magalhães Flávio , Damiani Ana Paula Moraes , Hamblin Michael R. , Zamunér Antonio Roberto , Ferraresi Cleber 
Published: May 2023

AbstractPhotobiomodulation therapy (PBMt) combined or not with oral hypoglycemic medication has not been investigated in type 2 diabetes (T2DM) patients. All 10 T2DM patients were assessed randomly at 6 different occasions (3 with and 3 without regular oral hypoglycemic medication). Capillary glycemia was assessed after overnight fast (pre‐prandial), 1 h postprandially (standardized meal, 338 kcal), and 30 min, 3 h, 6 h, 12 h post‐PBMt (830 nm; 25 arrays of LEDs, 80 mW/array). Three doses (0 J—sham, 100 J, 240 J per site) were applied bilaterally on quadriceps femoris muscles, hamstrings, triceps surae, ventral upper arm and forearm; and randomly combined or not with oral hypoglicemic medication, totaling six different therapies applied for all 10 TDM2 patients (PBMt sham, PBMt 100 J, PBMt 240 J, PBMt sham + medication, PBMt 100 J + medication, PBMt 240 J + medication). Cardiac autonomic control was assessed by heart rate variability (HRV) indices. Without medication, there was reduction in glycemia after all PBMt doses, with 100 J as the best dose that persisted until 12 h and presented lower area under the curve (AUC). With medication, glycemia decreased similarly among doses. No differences between 100 J and sham + medication, but AUC was significantly lower after 100 J, suggesting better glycemic control. Low frequency component of HRV increased after sham + medication and 100 J, suggesting higher sympathetic activation. PBMt showed time– and dose–response effect to reduce glycemia in T2DM patients. Effects on HRV were consistent with glycemic control.
Trapped in housing insecurity: Socioecological barriers to housing access experienced by intimate partner violence survivors from marginalized communities
Authors: Kulkarni Shanti J. , Notario Heidi 
Published: May 2023

AbstractHomelessness and intimate partner violence (IPV) do not impact all communities equally. Survivors from marginalized communities—that is communities that have been historically and structurally excluded from social, economic, and political resources—face additional challenges weathering IPV and housing crises. Understanding the housing experiences of marginalized survivors is necessary to achieve housing equity for all survivors. Community‐based participatory research methods were utilized to convene 14 listening sessions (7 primary/7 validation) with Black and Latinx IPV survivors with intersectional identities (n = 92). Listening sessions were held in community‐based locations including a church, health clinic, social service agency, and private residence. The last five validation sessions were conducted virtually on Zoom due to COVID pandemic protocols. All listening sessions were digitally recorded and transcribed verbatim. Latinx population listening sessions were conducted in Spanish and were implemented and translated with attention to linguistic justice principles. The research team used a modified constructivist grounded theory approach for data analysis. Four overarching themes (and seven subthemes) related to survivors' housing experiences emerged: (1) safety and healing challenges, including living in unhealthy physical environments, not being safe in their homes, and contending with community violence, sexual exploitation threats, and eviction fears; (2) formal service fragmentation/bureaucracy that hampered access to housing resource information and resources; (3) resource scarcity associated with limited affordable housing stock; and (4) systemic oppression resulting from discriminatory treatment and gentrification. Comprehensive multileveled approaches are needed to disrupt the cycle of housing insecurity for IPV survivors from marginalized communities.
Compressed 4‐day workweek for dental faculty retention and recruitment
Authors: Afshari Fatemeh S. , Guajardo Leticia , Kramer Jill M. , Musawi Ammar , Regasamy Venugopalan Shankar , Sykes‐Smith Anita 
Published: May 2023

AbstractFaculty recruitment and retention are major concerns faced by dental schools across the country. This increase in faculty shortage impacts training the next generation of clinicians and oral health care delivery in dental institutions, which together will exacerbate challenges related to access to dental care. The objective of this paper is to propose a compressed workweek as an incentive to improve recruitment, retention, and faculty well‐being. There are several well‐documented benefits of the 4‐day workweek which include employee wellness, increased job satisfaction, happiness, and improved perception of personal worth. Cost savings may be also realized with this schedule, as expenses related to transportation and dependent care costs could potentially decrease. Altogether, these benefits have been shown to lead to reduced absenteeism, anxiety, stress, and burnout. This perspective piece will discuss how the 4‐day workweek could be implemented in dental institutions, along with the benefits and challenges. Given the shortage of clinical faculty throughout the United States, we recommend this approach not only as a means to attract recent graduates to academia but also to ensure the retention of those who provide clinical instruction.