bluuebunny/crossref_metadata_2025_split huggingface dataset:
Title: Healthcare center wastewaters in Burkina Faso: sources of ESBL, AmpC-β-lactamase and carbapenemase producing Escherichia coli and Klebsiella pneumoniae
Authors: Garba Zakaria , Bonkoungou Isidore O.J. , Millogo Nadège O. , Natama H. Magloire , Vokouma Patrick P. A. , Bonko Massa dit A. , Karama Ibrahima , Tiendrebeogo Alix L. W. , Haukka Kaisa , Tinto Halidou , Sangaré Lassana , Barro Nicolas 
Published: January 2023

Abstract

Background
Extended-spectrum β-lactamase (ESBL), plasmid-mediated AmpC-β-lactamase and carbapenemase producing Escherichia coli and Klebsiella pneumoniae have spread into environment worldwide posing a possible public health threat. However, the prevalence data in low- and middle-income countries are still scarce. The aim of this study was to assess the occurrence of ESBL, AmpC-β-lactamase and carbapenemase producing and multidrug-resistant E. coli and K. pneumoniae in wastewater collected from healthcare centers in Burkina Faso.
Methodology
Eighty-four (84) wastewater samples were collected from 5 healthcare centers and bacterial counts on ESBL ChromAgar were performed. E. coli and K. pneumoniae isolates were identified using API20E. ESBL production was confirmed using the double disc synergy test (DDST). AmpC-β-lactamase detection was performed on Muller Hinton (MH) agar supplemented with cloxacillin (4µg/l). Carbapenemase testing was carried out using O.K.N.V.I. RESIST-5 immunochromatography test.
Result
E. coli and/ or K. pneumoniae strains were isolated from 82 wastewater samples (97.6%). In total, 170 strains were isolated, E. coli more commonly (64%). Average concentrations of ESBL producing bacteria per hospital varied from 1.10x105 to 5.23x106 CFU/ml. Out of 170 presumptive ESBL producing isolates and 51 presumptive AmpC-β-lactamase producing isolates, 95% and 45% were confirmed, respectively. Carbapenemase production was detected in 10 isolates, 6 were NDM producers, 3 were OXA-48 producers and 1 was NDM and OXA-48 producer. All isolates were multidrug resistant and, furthermore, all of them were resistant to all β-lactams tested. Also, resistance to ESBL inhibitors was common, up to 66% E. coli and 62% in K. pneumoniae. Amikacin, fosfomycin and nitrofurantoin were the antibiotics for which least resistance was detected.
Conclusion
This study showed that wastewater from healthcare centers constitutes a reservoir of multidrug-resistant bacteria in Burkina Faso, including those capable of producing carbapenemases, which may disseminate into environment and further back to humans. Therefore, following the microbiological quality of the wastewaters released from healthcare centers is important to include in the future national AMR surveillance program.
Transport in non-Hermitian quantum systems
Authors: Lima L. S. 
Published: January 2023

Abstract
Transport in non-Hermitian quantum systems is studied. The goal is a better understanding of transport in non-Hermitian systems like the Lieb lattice due to its flat bands and the integrability of the Ising chain which allows transport in that model to be computed analytically. This is a very special feature that is not present in a generic non-Hermitian system. We obtain the behaviour of the spin conductivity as a function of the non-Hermitian parameters of each system with aim to verify the influence of variation them on conductivity. For all models analyzed: Ising model as well as noninteracting fermion models, we obtain a little influence of the non-Hermitian parameters on conductivity and thus, a small effect over transport coefficients. Furthermore, we obtain an influence of opening of the gap in the spectrum in these models on longitudinal conductivity as well.
PACS numbers: 75.10.Pq, 75.40.Mg
Design of a Compact Dual-band Antenna for 2.4/5.8 GHz WLAN/WiFi Applications using Signal Interference Technique
Authors: Kumari Sadhana , Maurya Naveen Kumar 
Published: January 2023

Abstract
This manuscript presents a compact dual-band monopole antenna for WLAN/WiFi. The proposed antenna is comprised of a wideband monopole antenna integrated with a wideband bandstop filter (BSF). Within the proposed frequency band of operation, the proposed antenna exhibits good selectivity and low reflection loss. The measured results show that the proposed antenna can provide two separate impedance bandwidths; 290 MHz (about 12% centered at 2.4 GHz) and 500 MHz (about 9% centered at 5.5 GHz), making it suitable for WLAN operation in the 2.26-to-2.55GHz band and 5.3-to-5.8GHz. The observed VSWR is less than 2.2 and the peak antenna gain is 1.5 dBi within the frequency range. Performance analysis of the ultrawideband monopole antenna, BSF and their integrated counterpart has been carried out methodically in this paper. A consistency has been found between simulated and experimental results. Furthermore, the size of the proposed antenna is 35 x 27 x 1.6 mm3, which is quite compact and suitable for the WLAN/WiFi application.
Novel M-PCR assay for simultaneous detection of gastroenteritis associated viruses
Authors: Brar Basanti , Minakshi Prasad , Ikbal Ikbal , Ranjan Koushlesh , Misri Jyoti 
Published: January 2023

Abstract
Bovine Viral diarrheal virus (BVDV), bovine corona virus (BCV), and bovine picobirnavirus (BPBV) group I and II are most common viral infections in cattle that cause a huge economic loss across the world. A rapid and novel multiplex-PCR assay (M-PCR) was developed for simultaneous detection of BVDV, BCV and BPBV. Three primer pairs specific for each virus were used in the assay. Out of these three primer pairs, two pairs from M and 5’ UTR gene specific primer for BCV and BVDV respectively were self designed and .used for amplification. To evaluate the reliability of the multiplex assay, 300 buffalo faecal samples were tested by multiplex PCR assay. The results showed that 54(18%) samples were detected positive with multiple viruses including 50 samples were infected with BVDV, twenty eight samples were infected with BCoV and thirty nine samples were found infected with BPBV by M-PCR assay. In conclusion the developed assay is found highly specific, sensitive, high throughput and quick method for the detection of three viruses in a single reaction tube. This multiplex assay is successful tool that can be used for quick detection of these three viral infections for epidemiological investigation and in screening of clinical samples. To the best of our knowledge, this is the first time reported multiplex assay for the detection of BVDV, BCoV and BPBV throughout the world. This novel assay will be helpful for detecting mixed infections of GITs.
Classification of objects in Thermal Videos using a Dynamic STP and TTP based FCNN
Authors: D Sasireka , Juliet Ebenezer , D Jeyabharathi , D Kesavaraja 
Published: January 2023

Abstract

In today’s modern technology the thermal camera plays a major role in all security applications, surveillance applications, etc. And, in pandemic situations the thermal camera plays a major role, because of its nature of picture the scene based on the thermal radiation emitted by the objects in a scene. Hence, regardless of any weather conditions and lighting conditions, an object can be visualized. So, in general, there is huge demand for effective object classification system in thermal videos. The proposed system uses Dynamic STP (Spatial-Temperature Pattern) & TTP (Temporal-Temperature Pattern) based FCNN (Fully Convolutional Neural Network) for object classification in thermal videos. There are two novel methods used in the proposed system. First one is Temperature histogram-based object detection and another one is Dynamic STP & TTP based FCNN for object classification. The nature of FCNN cannot be fully utilized in thermal videos due to the lack of texture information. The dynamic STP & TTP is designed for each object as a kernel to extract the STP, TTP feature map of thermal videos. The fully connected layer with soft max classification is used for classification of objects. The experimental result shows that the proposed system outperforms the state of art methods.
Identification of small molecule inhibitors of CXCR4 – an important drug target in renal fibrosis
Authors: Kumar Senthil , E Elakkiya , Gupta Krishna Kant 
Published: January 2023

Abstract
The final stage of almost all chronic kidney diseases is renal fibrosis (CKD). Following tissue inflammation, the healing process leads to fibrosis. Simple wounds or persistent inflammation can cause tissue inflammation, which, in the case of the kidney, results in scarring. Vascular sclerosis, tubulointerstitial fibrosis, and glomerular fibrosis are all types of kidney fibrosis. Tubular atrophy, tubular dilatation, interstitial leukocyte infiltration, fibroblast accumulation, vascular rarefaction, and persistent matrix protein deposition make up the tubulointerstitial fibrosis histological appearance. Renal damage will therefore be exacerbated and fibrosis will be encouraged by persistently elevated Cxcr4 expression (on tubules or immune cells like macrophages). Since various effector cells, including tubular and infiltrating lymphoid cells, are involved in fibrosis, blocking this pathway should reduce it. This study aimed to identify possible pharmacological agents which could bind to and inhibit isoform I of CXCR4 and determine their strength of interactions. The I-TASSER, Phyre and Robetta were used to predict and refine the structure of the CXCR4 protein. ModBase was used to improve the loops, and then the quality was evaluated using the ERRAT value. The improved 3D structure was subjected to small molecule database docking using Maestro (from Schrodinger) and the glide module. GROMACS was used to simulate molecules with the lowest glide scores and the best ADME properties. For docking studies, we employed the CXCR4 refined structure, which had an ERRAT score of 92.15.%. The maximum glide score was achieved by the ligand 1-[(4-ETHYLPHENYL)METHYL]-4-[(3-NITROPHENYL)METHYL]PIPERAZINE, which was followed by 1-CYCLOHEXYL-4-[(2-NITROPHENYL)METHYL]PIPERAZINE. GROMACS simulation simulations revealed that 1-[(4-ETHYLPHENYL)METHYL]-4-[(3-NITROPHENYL)METHYL]PIPERAZINE and CIITA-I interacted in a more stable manner.
A Common Fixed Points Results for Multi-Valued Mappings in Hausdorff Modular Fuzzy b-Metric Spaces with Application Volterra-Type Integral Inclusion
Authors: MAKRAN Noreddine 
Published: January 2023

Abstract
The modular fuzzy b-metric space is defined in this study, and we are interested in proving a general common fixed point theorem for a pair multi-valued mappings in Hausdorff modular fuzzy b-metric spaces. The findings in this work generalize the findings in [15] and produce additional specific findings that are supported by examples. An application toprove the existence of an integral inclusion equation’s solution is shown to demonstrate theimportance of our result.
2010 Mathematics Subject Classification. Primary 47H10; Secondary 54H25.
“The Peripheral Perfusion Index Discriminates Haemodynamic Responses to Induction of General Anaesthesia”
Authors: Højlund Jakob , Petersen David René , Agerskov Marianne , Foss Nicolai Bang 
Published: January 2023

Abstract
Purpose: Induction of general anaesthesia is often accompanied by hypotension. Standard haemodynamic monitoring during anaesthesia relies on intermittent blood pressure and heart rate. Continuous monitoring systemic blood pressure requires invasive or advanced modalities creating a barrier for obtaining important information of the circulation. The Peripheral Perfusion Index (PPI) is obtained non-invasively and continuously by standard photoplethysmography. We hypothesized that different patterns of changes in systemic haemodynamics during induction of general anaesthesia would be reflected in the PPI.
Methods: PPI, stroke volume (SV), cardiac output (CO), and mean arterial pressure (MAP) was evaluated in 107 patients by either minimally invasive or non-invasive means in a mixed population of surgical patients. 2 minutes after induction of general anaesthesia relative changes of SV, CO and MAP was compared to the relative changes of PPI.
Results: After induction total cohort mean(±st.dev.) MAP, SV, and CO decreased to 65(±16)%, 74(±18)%, and 63(±16)% of baseline values. In the 38 patients where PPI decreased MAP was 57(±14)% , SV was 63(±18)%, and CO was 55(±18)% of baseline values 2 minutes after induction. In the 69 patients where PPI increased the corresponding values were MAP 70(±15)%, SV 80(±16)%, and CO 68(±17)% (all differences: p < 0,001).
Conclusion: During induction of general anaesthesia changes in PPI discriminated between the degrees of reduction in cardiac stroke volume and -output, and blood pressure. As such, the PPI has potential to be a simple and non-invasive indicator of the degree of post-induction haemodynamic changes.
Phylogenetic relationship among species of Rubus L. (Rosaceae) from southern Western Ghats of India: Morphological data aligns with the combined dataset of plastid and nuclear markers
Authors: Narayanan Bhavadas , Thara Umesh B. , Ramanujan Rahul P. 
Published: January 2023

Abstract

The present study explores the taxonomic delineation of Rubus taxa within south Western Ghats of India. Most of the species are aligned in two major subgenera, Idaeobatus and Malachobatus but were lacking systematic botany. The external morphological study developed fine dichotomous key characters for the discrimination of Rubus under study, but it was inadequate for the closely allied species. Therefore, the delineation of the taxa was studied by using the alignment of molecular sequences from three barcode regions (matK, rbcL, and nrITS) and phylogenetic tree of plastid (matK + rbcL), nuclear (nrITS), and combined (plastid + nuclear) genome was constructed for taxa discrimination. Fifteen Rubus collections were comparatively analyzed for the phylogenetic analysis including the inter-specific distance of eleven taxa and the intra-specific distance of four species. It was observed that the nuclear ITS marker had much higher sequence variations compared to the other loci. Phylogenetic relationship within Rubus is well resolved in combined datasets than nuclear and plastid data separately and in this study, the analyzed samples included in both Idaeobatus and Malachobatus formed a polyphyletic clade in all datasets except plastid phylogeny. Wherein the plastid genome, subgenus Malachobatus have shown more conserved sequences than subgenus Idaeobatus. Whereas, subgenus Malachobatus had shown limited species resolution than Idaeobatus in all barcode markers because a group of species belonging to subgenus Malachobatus has shown inadequate genetic variations within species similar to its limited morphological variability. Hence we considered this group a complex species among southern Western Ghats Rubus and it is recommended further clarification.
Quantum interference effects in graphene based side-coupled quantum ring: A non-equilibrium Green's function approach
Authors: Seyfizadeh P. , Phirouznia A. 
Published: January 2023

Abstract
The present study investigates the I-V and spin-transport characteristics of a side-coupled graphene nano-ring. Where, non-equilibrium Green's function approach has been employed as computational framework. Meanwhile the effect of substrate induced Rashba interaction has been considered as a source of spin-dependent processes in the transport phenomena. Calculations have been performed within the coherent regime in which the electric and spin currents of the system are given as a function of bias voltage and Rashba coupling strength. Results show that Aharonov-Bohm oscillations and Fano factor could be changed by the Rashba coupling strength. The Rashba interaction can change the Fano factor from the Poisson to sub-Poisson regime in the case of armchair leads.
Microbial detoxification of Pyrethroid insecticide Bifenthrin by selected Fungal strains and Optimizing conditions using Response Surface Methodology
Authors: Majid Sara , Ahmad Khuram , Ali Daoud 
Published: January 2023

Abstract
Bifenthrin is broad spectrum type I pyrethroid insecticide, used broadly for agricultural and urban purposes, yet very little is reported about its biodegradation. Five fungal strains named Aspergillus niger (Asp-N), Aspergillus flavus (Asp-F), Aspergillus fumigatus (Asp-Fu), Penicillium chrysogenum (PC) and Lasiodiplodia theobromae (LD) were utilized to degrade bifenthrin for 35 days incubation time. PC is found to be extremely effective in degrading Bifenthrin up to 85%. Furthermore, response surface methodology (RSM) with Box-Behnken design is applied to optimize the degradation conditions with varying pH, temperature (℃) and incubation time (days). The response surface design and analysis of variance depicted the p-value below 0.05 indicating the significance of reaction parameters. The optimal ranges for degrading BF (10 mg/L) by PC were determined to be 30 oC, pH-7 and 24-days incubation period. This fungal strain co-metabolized BF in eutrophic condition within glucose rich medium. The PC degrade BF by hydrolytic cleavage of carboxyl-ester linkage as chromatogram obtained by GCMS with four metabolites. This research provides new insights into the biodegradation of BF by strain Penicillium chrysogenum (PC).
Micromechanical based model for predicting aged rubber fracture properties
Authors: Kadri R. , Abdelaziz M. Nait , Fayolle B. , Ayoub G. , Hassine M. Ben , Nziakou Y. 
Published: January 2023

Abstract

Environmental aging induces a slow and irreversible alteration of the rubber material’s macromolecular network. This alteration is triggered by two mechanisms which act at the microscale: crosslinking and chain scission. While crosslinking induces an early hardening of the material, chain scission leads to the occurrence of dangling chains responsible of the damage at the macromolecular scale. Consequently, the mechanical behavior as well as the fracture properties are affected. In this work, the effect of aging on the mechanical behavior up to fracture of elastomeric materials, and the evolution of their fracture properties are first experimentally investigated. Further, a modeling attempt using an approach based upon a micro-mechanical but physical description of the aging mechanisms is proposed to predict the mechanical and fracture properties evolution of aged elastomeric materials. The proposed micro-mechanical model incorporates the concepts of residual stretch associated with the crosslinking mechanism and a so-called “healthy” elastic active chain (EAC) density associated with chain scission mechanism. The validity of the proposed approach is assessed using a wide set of experimental data either generated by the authors or available in the literature.
Pseudoaneurysm after aortopulmonary window repair and bilateral lung transplantation for Eisenmenger syndrome: a case report
Authors: Nagashima Toshiaki , Taira Masaki , Hasegawa Moyu , Kugo Yosuke , Watanabe Takuji , Yoshioka Daisuke , Shimamura Kazuo , Ueno Takayoshi , Miyagawa Shigeru 
Published: January 2023

Abstract
Background
Aortopulmonary window (APW) is a rare congenital cardiac anomaly characterized by communication between the main pulmonary artery and ascending aorta.
There are various surgical techniques, and the short- and long-term results are excellent if the surgical repair is performed early in life. To the best of our knowledge, there have been no reports of pseudoanuerysm after APW repair. Herein, we present a case of a 30-year-old woman with an ascending aortic pseudoanuerysm found at the site of APW repair nine months after the APW repair and bilateral lung transplantation.
Case presentations
A 30-year-old woman presented with APW and Eisenmenger syndorome. The patient underwent APW repair and bilateral lung transplantation. We transected the communication between the aorta and pulmonary artery and closed the aortic side directly with strips of felts.
Nine months after the surgery, the patient complained of chest pain. Cardiac computed tomography revealed an ascending aortic pseudoanyeurysm at the anastomotic site.
Emergent graft replacement of the ascending aorta was performed and the postoperative course was uneventful.
Conclusions
We have experienced a case of a pseudoaneurysm at the anastomotic site after APW repair and bilateral lung transplantation.
The choice of surgical technique should be based on the patient’s background requiring lung transplantation, and close postoperative follow-up is required.
Design and evaluation of performance dashboard for paramedical faculty of Army University of Medical Sciences: Protocol for a mixed method study
Authors: Almasi Sohrab , Mehrabi Nahid , Ghorbani Mahdi 
Published: January 2023

Abstract

Background
Faculty, as an educational system, comprises a combination of various educational groups, faculty members, researchers, students, and administrative staff. Each group of faculty members contributes to different fields. The management of data records related to the performance and activities of the faculty and its members leads to better monitoring, identification of weaknesses and strengths, and, ultimately, promotion of the performance of the faculty. In fact, the dashboard is a data management tool that can be used for monitoring and evaluating a faculty’s performance.
Objectives
Therefore, the aim of this study was to design a functional dashboard for the faculty of paramedical sciences and evaluate its functionality using the approach of sequential mixed methods.
Methods
This is a mixed methods study with sequential mixed designs that will be conducted in four main phases. In the first phase, all the resources related to the functional dashboard are reviewed in order to identify its operational requirements. In the second phase, the requirements and necessities of the software are determined by both qualitative (interview) and quantitative (Delphi) methods. In this phase, eight people will be interviewed during the qualitative phase, and thematic analysis will be used to analyze the data. For the quantitative step, the two- round Delphi technique will be conducted by the purposeful selection of 21 individuals. In the third phase, code writing of the software is performed using C-Sharp programming language in the Visual Studio environment. Finally, 15 people among faculty members and managers, who are users of the dashboard software, are selected to evaluate the software. Users’ satisfaction with the dashboard software is assessed using the Dashboard Assessment Usability Model. The data will be analyzed using descriptive statistics and SPSS version 21 software.
Conclusion
The final product of this study is a dashboard for monitoring, evaluating performance, and managing resources at the faculty level. The steps of designing this dashboard can be a basis for developing better dashboards for evaluating other faculties or universities.