bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE EXAMINATION OF DOODLE ILLUSTRATION STUDIES BY BARTHES' SEMIOTIC ANALYSIS METHOD
Authors: KUM Özlem 
Published: December 2022

Semiotics is a branch of science that includes the processes of examining, interpreting and re-interpreting signs with the system of "Signifier", "Signifier", "signified". In semiotic analysis, besides the direct messages, the messages that are wanted to be conveyed indirectly are revealed. In this article, it is aimed to examine 10 randomly selected Doodle illustrations from the Doodle archive of 2022 using Barthes' semiotic analysis method. Azah Aziz's birthday, Indonesian Independence Day, Japan's Mountain Day, Kimiko Tsumura's 120th birthday, India Independence Day, Doodle designed for “Google”, Seiki Kuroda's 156th birthday, Qixi Festival, Luisa de Medrano's 538th birthday, Singapore National Day illustration works are analyzed.
In the article, literature review was used to obtain theoretical information about Doodle illustration works, and Barthes' semiotic analysis method was used for the analysis of randomly selected Doodle illustration works.
While the Google company used to publish Doddles only for important days, today it has gone to design diversification in different categories; It includes designs in its corporate image for birthdays of famous people, holidays, festivals, special days of countries (independence day, mountain day, etc.), national days as animation and video content, not just visuals.
It has been concluded that the birthdays of famous people, independence days of countries, mountain days, festivals, national days are thematically analyzed in Doodle studies, which are analyzed semiotically. It is noteworthy that typographic arrangements are frequently used in Doodle works, and that typographies are deformed and adapted to the design in an integrated manner with the visual. It has been concluded that the use of color directly reflects the subject it deals with or the characteristics of the culture it represents, and that Doodle impersonates the theme in the context of technical and color use.
Optimization of Process Parameters for L-Glutaminase Production by Pseudomonas Species ALG3
Authors: Okpalla J. , Dim L. O. , Onyekuru D. A. , Duru I. E. , Mba T. O. 
Published: December 2022

The present study reports the optimization of process parameters for L-glutaminase production by Pseudomonas species ALG3. The L-glutaminase –producing bacterium had already been isolated from soil at a location within Chukwumemeka Odumegwu Ojukwu University, Uli in Anambra state. It was identified using cultural, biochemical and molecular characteristics. Optimization of L-glutaminase production was done by assessing the effect of various parameters using mineral salt medium contained in 250 ml flasks. The parameters included various bivalent metals, pH, surfactants, growth promoters, amino acids and fermentation time. The Results showed that the addition of FeSO4 stimulated optimum L-glutaminase yield of 38.36 U/ml by Pseudomonas species ALG3, while the least production was observed with MnSO4. Enhanced L-glutaminase yield of 30.73 U/ml was recorded at pH 8.0, while the lowest enzyme accumulation was observed at pH 9.0. The highest L-glutaminase accumulation of 82.25 U/ml was achieved with Tween 80, while the lowest yield was recorded with stearic acid. Urea, stimulated maximum L- Glutaminase yield of 43.82 U/ml, while minimum accumulation was observed with peptone. Proline stimulated highest L- glutaminase yield of 42.63U/ml, while the lowest yield was observed with tyrosine. Highest L- glutaminase yield (91.88 U/ml) was observed after 72h, the yield decreased thereafter. The results obtained in the study illustrated that the optimization of process parameters, increased appreciably the L-glutaminase yield of Pseudomonas species ALG3. This suggest that Pseudomonas species can be used for large scale production of L- glutaminase, which can offer great potential for applications in Medicine and food industry.
Calculation of Cohesive Energies of 3-D Bismuth Selenide (Bi2Se3) and Bismuth Antimony BiSb Topological Insulators: DFT Study
Authors: Hemba E. C. , Ikyumbur T. J. , Trisma E. A. , Gbaorun F. , Aungwa F. 
Published: December 2022

The cohesive energies of 3-dimensional (3-D) topological insulators bismuth antimony (BiSb) and bismuth selenide (Bi2Se3) were calculated. The Fritz Haber Institute Ab-initio molecular simulations (FHI-aims) code was employed for this calculation. The output files of the FHI-aims code were used during the computation and the total energies at each number of iterations for single free atoms and bulk were then calculated. The results from this work revealed that bismuth atom becomes stable at 3rd iteration meanwhile both selenium and antimony atoms gain stability at the 5th iteration. The results also showed that bismuth antimony acquire stability at the 3rd iteration and bismuth selenide gain stability at 9th iteration. This implies that among the free atoms studied in this work bismuth atom is more stable and for the bulk bismuth antimony is more stable. The cohesive energies of BiSb and Bi2Se3 were calculated using the optimized parameters. The results obtained from the calculation of the cohesive energies in this work were 1.02eV and 1.76eV for BiSb and Bi2Se3 respectively. This results compared reasonably well with experimental results and have little percentage errors of 1.30% for bismuth antimony and 29.55% for bismuth selenide. The deviation observed in this work may be due to the DFT calculation of the solid rather than the atoms themselves.
Successful Surgical Treatment of Stage IVB Immature Teratoma Involving the Liver and Thoracic Cavity, With Combination Chemotherapy: A Case Report
Authors: Park Eun-Kyu , Song Sang Hwa , Koh Yang Seok 
Published: December 2022

Introduction
Immature teratomas are very rare tumors, representing only 1% of ovarian cancers. Distant metastases to the liver effect late disease manifestation, rendering chemotherapy the only viable option.

Case presentation
Here, we report the successful surgical management of stage IVB immature teratoma after cisplatin-based chemotherapy. A 20-year-old woman presented with a huge abdominal palpable mass and dyspnea. Postoperative pathology confirmed immature teratoma with metastases to the liver, diaphragm, and thoracic cavity (stage IVB). The patient underwent right hemihepatectomy, diaphragm resection, thoracic mass resection, and diaphragm repair using aortic artificial graft. She did not receive postoperative adjuvant chemotherapy. After the complete surgical resection of the tumor, the patient had no recurrence during the 44-month follow-up period.

Conclusion
No established treatment modalities have been developed for further treatment, once the first-line combination chemotherapy achieves unfavorable results in stage IVB immature teratoma. Surgical resection may offer hope for excellent disease control in this dismal stage. To obtain best possible outcomes, coordinated care between oncologists and general surgeons is required.
Multifold Fermions and Fermi Arcs Boosted Catalysis in Nanoporous Electride 12CaO·7Al2O3
Authors: Meng Weizhen , Zhang Xiaoming , Liu Ying , Dai Xuefang , Liu Guodong , Gu Yuantong , Kenny E. P. , Kou Liangzhi 
Published: December 2022

AbstractTopological materials have been recently regarded as ideal catalysts for heterogeneous reactions due to their surface metallic states and high carrier mobility. However, the underlying relationship between their catalytic performance and topological states is under debate. It has been discovered that the electride 12CaO·7Al2O3 (C12A7:4e−) hosts multifold fermions and Fermi arcs on the (001) surface near the Fermi level due to the interstitial electrons. Through the comparison of catalytic performance under different doping and strain conditions, based on the hydrogen evolution process, it has been demonstrated that the excellent catalytic performance indeed originates from topological properties. A linear relationship between the length of Fermi arcs, and Gibbs free energy (ΔGH*) has been found, which not only provides the direct evidence to link the enhanced catalytic performance and surface Fermi arc states, but also fully clarifies the fundamental mechanism in topological catalysis.
Avoiding bias in artificial intelligence
Authors: Gudis David A. , McCoul Edward D. , Marino Michael J. , Patel Zara M. 
Published: December 2022

AbstractArtificial intelligence (AI) is ubiquitous and expanding, and the healthcare industry has rapidly adopted AI and machine learning for numerous applications. It is essential to understand that AI is not immune to the biases that impact our clinical and academic work, and in fact may inadvertently amplify rather than reduce them. As we harness the power of AI, it is our obligation to our patients to ensure that we address these concerns. We must take responsibility for proactive stewardship to protect against bias, not only for new AI algorithms, but also for our research studies that may one day provide data for those algorithms.
An Atomically Precise Pyrazolate‐Protected Copper Nanocluster Exhibiting Exceptional Stability and Catalytic Activity
Authors: Wang Yu‐Mei , Lin Xiao‐Chun , Mo Kai‐Ming , Xie Mo , Huang Yong‐Liang , Ning Guo‐Hong , Li Dan 
Published: December 2022

AbstractThe synthesis of atomically precise copper nanoclusters (Cu‐NCs) with high chemical stability is a prerequisite for practical applications, yet still remains a long‐standing challenge. Herein, we have prepared a pyrazolate‐protected Cu‐NC (Cu8), which exhibited exceptional chemical stability either in solid‐state or in solution. The crystals of Cu8 are still suitable for single crystal X‐ray diffraction analysis even after being treated with boiling water, 8 wt % H2O2, high concentrated acid (1 M HCl) or saturated base (≈20 M KOH), respectively. More importantly, the structure of Cu8 in solution also remained intact toward oxygen, organic acid (100 eq. HOAc) or base (400 eq. dibutylamine) confirmed by 1H NMR and UV/Vis analysis. Taking advantage of high alkali‐resistant, Cu8 illustrates excellent catalytic activity for the synthesis of indolizines, and it can be reused for at least 10 cycles without losing catalytic performance.
β‐Ketoenamine‐Linked Covalent Organic Framework with Co Intercalation: Improved Lithium‐Storage Properties and Mechanism for High‐Performance Lithium‐Organic Batteries
Authors: Wang Han , Zou Wentao , Liu Chao , Sun Yi , Xu Yi , Sun Weiwei , Wang Yong 
Published: December 2022

AbstractAs a new kind of crystalline porous polymers, covalent organic frameworks (COFs) exhibit great potential as electrode materials for rechargeable metal‐ion batteries due to their stable and adjustable structure, high porosity and abundant electrochemical active centers. In this paper, facile one‐step synthesis process is proposed to obtain the cobalt ion intercalated two‐dimensional β‐ketoenamine‐linked COF (Co−DAAQ−TFP‐COF, denoted as Co‐COF). The intercalation of Co ion in adjacent two layered structure of COF via coordination effects can activate the Li+ storage ability of aromatic ring in the original COF, greatly improve the utilization of redox active sites, shorten the migration length of electrons and ions, and promote fast lithium reaction kinetics. Adopted as the anode for lithium‐ion batteries, substantial improvement on the reversible capacity and cycling performance can be achieved for the obtained Co intercalated COF electrode (780 mAh g−1 after 200 cycles at 100 mA g−1) compared to original COF electrode (120 mAh g−1 under the same condition). The two‐dimensional COF materials with morphology justification and/or performance improvement via metal ion intercalation would promote the application of COF related electrodes for other energy‐storage fields.
2021 U.S. Virgin Islands Zika health brigade: Providing recommended pediatric health screenings for children born to mothers with laboratory evidence of possible Zika virus infection during pregnancy
Authors: de Wilde Leah H. , Harrison Cosme Jeremy , Ceesay Binta E. , Mayers Charmaine S. , Ferrol‐Hawley Janney , Canton Jacqueline , Godfred‐Cato Shana , Reynolds Megan R. , Brown‐Shuler Lessely , Randhawa Sukhdeep , Schoelles Dan , Hillman Braeanna , Carlos Maria Paz , Ambrose Tracey , Bitner Derek , Holgado Sandra , Jones Cristie , Lattin Daniel J. , Mulkey Sarah B. , Nguyen Angeline , Payne Mary , Prakalapakorn S. Grace , Shue Ann , Ellis Esther M. 
Published: December 2022

AbstractBackgroundThe United States Virgin Islands (USVI) Department of Health (DOH) conducted a second Zika health brigade (ZHB) in 2021 to provide recommended Zika‐related pediatric health screenings, including vision, hearing, neurologic, and developmental screenings, for children in the USVI. This was replicated after the success of the first ZHB in 2018, which provided recommended Zika‐related pediatric health screenings to 88 infants and children exposed to Zika virus (ZIKV) during pregnancy.MethodsTen specialty pediatric care providers were recruited and traveled to the USVI to conduct the screenings. USVI DOH scheduled appointments for children included in CDC's U.S. Zika Pregnancy and Infant Registry (USZPIR). During the ZHB, participants were examined by pediatric ophthalmologists, pediatric audiologists, and pediatric neurologists. We report the percentage of participants who were referred for additional follow‐up care or given follow‐up recommendations in the 2021 ZHB and compare these referrals and recommendations to those given in the 2018 ZHB.ResultsThirty‐three children born to mothers with laboratory evidence of ZIKV infection during pregnancy completed screenings at the 2021 ZHB, of which 15 (45%) children were referred for additional follow‐up care. Ophthalmological screenings resulted in the highest number of new referrals for a specialty provider among ZHB participants, with 6 (18%) children receiving referrals for that specialty. Speech therapy was the most common therapy referral, with 10 (30%) children referred, of which 9 (90%) were among those who attended the 2018 ZHB.ConclusionsThirty‐three children in a jurisdiction with reduced access to healthcare specialists received recommended Zika‐related pediatric health screenings at the ZHB. New and continuing medical and developmental concerns were identified and appropriate referrals for follow‐up care and services were provided. The ZHB model was successful in creating connections to health services not previously received by the participants.
C3 – Carbon Concrete Composite – Vom größten Bauforschungsprojekt zum bedeutendsten Verband für Carbonbetonbau
Authors: Kranich Sandra , Schladitz Frank 
Published: December 2022

AbstractCarbonbeton findet zunehmend Anwendung in der Praxis: im Neubau und im Bereich der Sanierung. Zahlreiche Unternehmen, Verbände und Institutionen arbeiten unter der Dachmarke von C3 – Carbon Concrete Composite daran, den Einsatz der Carbonbetontechnologie zu erleichtern, die zahlreichen Vorteile von Carbonbeton zu nutzen und somit einen wesentlichen Beitrag zur Klimaneutralität zu leisten. Dieser Aufsatz beschreibt die Anfänge der in den 1990er‐Jahren abwegig klingenden Idee und skizziert die Entwicklungsphasen von einem Bauforschungsprojekt zum bedeutendsten Verband auf dem Gebiet des Bauens mit Carbonbeton.
Repurposing antimalarial artesunate for the prophylactic treatment of depression: Evidence from preclinical research
Authors: Huang Shihao , Galaj Ewa , Wang Jinfeng , Guo Yi , Wang Shuang , Shi Mengxu , Yin Xueyong , Liu Keyao , Luo Yixiao , Meng Li , Shi Haishui 
Published: December 2022

AbstractIntroductionSeveral studies have linked inflammation and oxidative stress with the pathogenesis of depression. Artesunate is a commonly used medication to treat malaria and has been shown to produce antioxidant, anti‐inflammatory, and immunomodulatory effects. However, its prophylactic effects on depression and depression‐related brain pathology are unknown.MethodsIn Experiment 1, using a PC12 cell line, we investigated whether artesunate can prevent hydrogen peroxide (H2O2)‐induced oxidative injury that mimics oxidative stress commonly observed in the depressed brain. Next, using lipopolysaccharide (LPS)‐induced mouse model of depression, we investigated whether artesunate can prevent behavioral deficits observed in the open field test, novelty‐suppressed feeding test, sucrose preference test, forced swimming test, and tail suspension procedure.ResultsWe found that artesunate significantly prevented a H2O2‐induced reduction in PC12 cell activity, suggesting its antioxidant potential. We also found that mice pretreated with artesunate (5, 15 mg/kg) intraperitoneally (i.p.) prior to the LPS (.8 mg/kg, i.p.) treatment showed fewer and less severe depression‐ and anxiety‐like behaviors than the LPS‐treated control mice.ConclusionOur findings indicate that artesunate produces antioxidant effect, as well as antidepressant and anxiolytic effects. Importantly, our findings first demonstrate that artesunate can prevent LPS‐induced depression‐ and anxiety‐like symptoms, strongly suggesting its prophylactic potential in the treatment of depression and, perhaps, other psychiatric disorders associated with inflammation and oxidative stress.
Deciphering the Antimicrobial Potential of Taxus wallichiana Zucc: Identification and Characterization Using Bioassay‐Guided Fractionation
Authors: Adhikari Priyanka , Agnihotri Vasudha , Suman Sunil Kumar , Pandey Anita 
Published: December 2022

AbstractTaxus wallichiana Zucc. is a high valued medicinal plant and has been mainly studied for its anti‐cancer properties. However, research on its other important biological activities, such as its antimicrobial potential, still needs attention. The focus of the present study is to investigate the antimicrobial activity of secondary metabolites of T. wallichiana needles against 3 different groups of microorganisms, i. e., bacteria, actinobacteria, and fungi. Bioactive compounds from T. wallichiana needles were separated through column chromatography, and, TLC‐bioautography. Mobile phases were optimized using Snyder's selectivity triangle. Antimicrobial spots were fractionated and compounds were identified by gas chromatography‐mass spectroscopy (GC/MS) and liquid chromatography‐mass spectrometry (LC/MS). Functional groups were characterized using Fourier transform infrared spectrometry (FTIR) and nuclear magnetic resonance (NMR) was used to identify the molecular structures. GC/MS and LC/MS data analysis confirm the presence of fatty acids (arachidic acid, behenic acid, palmitic acid, and stearic acid), vitamins (nicotinamide), and alkaloids (cinchonine, timolol), aminobenzamides (procainamide), carbocyclic sugar (myoinositol), and alkane hydrocarbon (hexadecane), having antimicrobial activity in the needles of T. wallichiana. To the best of our knowledge, this is the first report on the isolation and characterization of antimicrobial compounds from the needles of Taxus wallichiana (Himalayan yew). The data obtained from the present study will be supportive to the new drug discoveries in modern medicine with various combinations of medicinal plant's active constituents that can be used for curing many diseases.
Renal vein thrombosis after COVID‐19: A case report
Authors: Janbazi Roudsari Hamid , Negaresh Mohammad , Shirzadeh Vida , Mohammadzadeh Germi Bahman , Mirzaei Arezoo 
Published: December 2022

AbstractSevere cases of coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome‐Coronavirus‐2, can lead to pneumonia or acute respiratory distress syndrome. Non‐respiratory manifestations of COVID‐19 include venous and arterial thrombosis. The disease can affect all organs and even the kidneys and lead to renal vein thrombosis where renal veins or their branches become thrombotic leading to symptoms such as flank pain, hematuria, or acute kidney damage. In this study, a case of renal vein thrombosis after COVID‐19 is introduced and the causes and complications of this disease are analyzed.
An adaptive phase‐locked loop‐less control strategy for LCL‐filtered grid‐connected inverter under complex grid conditions
Authors: Huang Min , Chen Fan , Wu Weimin , Yao Zhilei 
Published: December 2022

SummaryThe phase‐locked loop, as a method to extract grid voltage phase angle, is commonly used for grid‐connected inverter to synchronize the injected grid current with the grid. However, the phase‐locked loop will also bring some problems. The current loop controller, the phase‐locked loop, and the grid impedance are coupled together under the weak grid. Then, the phase angle of the inverter output impedance will be reduced, causing the system to be unstable. Moreover, the output phase angle of the phase‐locked loop participates in the coordinate transformation under the unbalanced grid voltage condition, which degrades the quality of the injected grid current generated by the inverter with high harmonic content. Therefore, a vector current control strategy without phase‐locked loop derived from direct power control is used in this paper. An adaptive linear Kalman filter algorithm is also applied to observe the voltage information and avoid the harmonic problems caused by power calculation. Finally, simulations and experiments are conducted to verify that the proposed method is effective, and the results are consistent with the theoretical analysis.
Volunteer Angling and Technology-Based Solutions Provide the First Estimate of Sea Lice Infections for Wild Coastal Cutthroat Trout Oncorhynchus clarkii clarkii
Authors: Losee James P , Dapp Derek R , Madel Gabe , Shimek Greg 
Published: December 2022

Abstract
Anadromous Coastal Cutthroat Trout Oncorhynchus clarkii clarkii are one of the least studied salmonids but are a highly prized target in sport fisheries in coastal waters of the Pacific Northwest. Despite an observed high prevalence of ectoparasite infections, described by sport anglers as “sea lice,” there is a paucity of data available on the spatial and temporal occurrence of infections on Coastal Cutthroat Trout. We collaborated with the angling community through social media engagement and an online application to report ectoparasites observed on sport catch. In 2018, we received voluntary reports for 1,493 Cutthroat Trout and 416 salmon catch events in marine waters from the province of British Columbia and the states of Washington, Oregon, and California. These data demonstrated that the number of argulids and copepods per trout varied according to body size, capture month, and area. To evaluate accuracy of voluntary parasite counts, we compared results to parasite counts on cutthroat from sampling events conducted by trained biologists. For both voluntary angler reports and those of biologists, spring months had a lower prevalence of argulids and copepods, argulids were common on trout, but absent on salmon, and larger trout were associated with an increased number of argulid and copepod infections.