bluuebunny/crossref_metadata_2025_split huggingface dataset:
Formation of Students’ Legal Consciousness and Civic Position in Higher Education Institutions
Authors: Abakumova I. V. , Matveeva O. A. 
Published: July 2023

Introduction.The principles and values, which form and keep functioning the civil society, should be a priority for all the present and future generations of citizens of the country. At the same time, the theoretical understanding of these categories should be backed up by their practical implementation. Therefore, the article aims at conducting the experimental pedagogical study of the problematic aspects of legal consciousness development for enabling a comprehensive assessment of the civic position maturity level of higher education teachers and students.Materials and Methods.The pedagogical activity management process in a Higher Education Institution and the work of tutors served the material for the present research. The research was conducted using a set of general scientific and specific scientific methods targeted at analysis and systematisation of the relevant materials, as well as at practical and experimental investigation.Results.The content of educators’ and students’ work on development of self-consciousness was considered during both in-class and extracurricular activities. Among the fundamental principles of the pedagogical activity management, the principles of legal consciousness and citizenship, democracy, as well as tolerance and civic actions engagement experience were defined. The features of tutors' work targeted at students’ legal consciousness and civic position formation were also analysed. In addition, the article focused at the need to form and strengthen partnerships with the general public, educational institutions, authorities and business.Discussion and Conclusions.The manageability of the civic self-consciousness development process has been revealed as the main result of the authors’ analytical research. The essential pedagogical requirements for this process have been distinguished: setting up interaction among all participants of this process both during educational as well as extracurricular activities, considering student professional training specifics and involvement of the general public into the process of self-consciousness development. The need to sensitize the teaching methods fostering students’ legal consciousness and citizenship formation has also been mentioned among the pedagogical requirements. The efficiency has been proved of setting up the temporary pedagogical communities of experts working directly with students and elaborating the specialised approaches designated to form the above-mentioned qualities in students through promotion of the special topics and issues within the curricula courses, the study of which can multiply the efficiency of the civil legal consciousness development efforts. The tutor activities programme aimed at students’ civic position formation has been worked out and suggested; step-by-step monitoring of students’ civic position formation process has also been envisaged.
Remote Sensing Detection and Resource Utilisation of Urban Sewage Sludge Based on Mobile Edge Computing
Authors: Hu Weijie , Zhou Youfei , Lu Junying , Sheng Jun , Jin Zechen 
Published: July 2023

Abstract
Improper disposal of municipal sewage sludge poses a significant threat to effective environmental protection. With the continuous advancement of artificial intelligence technology and the Internet of Things (IoT), remote sensing detection technology is emerging as a promising research avenue to address this issue. However, the current state of real-time detection technology is inadequate, hindering comprehensive and stable monitoring operation. Additionally, the rational use of network resources remains suboptimal. To address this challenge, this study proposes a resource optimisation technology for the current insufficient intelligent monitoring system of urban sewage sludge. By leveraging IoT and wireless technology, water meter data can be collected with minimal earth construction compared to traditional PLC collection. This is followed by utilising Faster R-CNN to plan the network transmission of sewage remote sensing information resources. Finally, the architecture collection module’s scalability is enhanced by incorporating edge computing and reserving sensor ports to meet future plant expansion demands. The experiment demonstrates the significant potential of this technology in application and resource optimisation. In actual parameter tracking tests, the proposed method effectively monitors sewage sludge, providing policy guidance and measure optimisation for relevant authorities, ultimately contributing to pollution-free urban development.
Correspondence distribution over a network in designing public urban passenger transportation tasks
Authors: Fadeev A. I. , Iliankov A. M. , Ukaderov V. V. 
Published: July 2023

Introduction. The process of planning public transport is divided into a few number of tasks in strategic, tactical and operational levels, which include the development route system, the establishment of traffic intensity along routes, the design of the structure of road transport vehicles, the distribution of the current road transport vehicles along the routes, determining the required amount of the subsidies, etc. Materials and methods. The article presents a multi-criteria mathematical model of transportation design, according to which the tasks have been solved by distributing (limited or unlimited) transport resources between the permissible routes of the transport network in accordance with a variety of efficiency criteria, which can be the subject to appropriate restrictions. The formation acceptable routes on the transport network can be carried out by means of the algorithms developed, for example, in the framework of solving TNDP and TNDFSP tasks. The routes can also be adjusted by experts. Transport demand is set by a matrix of passenger correspondence generated for the entire period of traffic on a weekday, to ensure that all passenger flows along the route network are taken into account, and not only the periods of the greatest traffic intensity. The calculation of the parameters of the transport offer in the process of solving the problems of transportation design is carried out based on the results of the passenger correspondence distribution on the route network (PAP), which is a complex problem unsolved today. The article describes the developed PAP methodology based on a flexible passenger strategy that takes into account the waiting time for transport, the proximity of the route through an empirical model of dividing demand by the length of trips, the preferences of transport modes, the possible redistribution of passenger flows between the stopping points of the network located within a walking distance. Results. The tasks of designing public transport transportation have been formulated, a multi-criteria mathematical model of their solution has been developed. The method of distribution of passenger flows on the route network based on a flexible passenger strategy has been described. The effectiveness of the developed PAP methodology is shown on test calculations, which were carried out using passenger correspondence, an average weekday in October 2019, obtained by processing validations of e-tickets of urban passenger transport in Krasnoyarsk. Discussion and conclusion. The practical implementation of the described methodology for the distribution of passenger flows on the route network using relational database management systems (DBMS) MS SQL Server has been carried out.
Indonesian Version of DREEM Short Form Construct Validity Test in Measuring Student Perception of Distance Learning Environment
Authors: Lutfiana Aviva , Salim Rose Mini Agoes 
Published: July 2023

English: The learning environment is very important to support student achievement. During the COVID-19 pandemic until the new normal transition, students are faced with a changing learning environment, starting from online, hybrid, to full offline. Dundee Ready Education Environment Measure (DREEM) is an instrument that measures students' perceptions of their learning environment in medical institutions developed by Roff, et.al. (1997). DREEM initially consist of 50-item to measure five domains, it was later developed into a 12-item short version by Jeyashree, Shewade, and Kathrivel (2018). There is no adapted version of DREEM short-form for non-medical institutions in Indonesia. Therefore, this study aims to adapt and validate the DREEM short-form measurement tool for a wider range of institutions. The population of this instrument testing are students in Indonesia with a sample of 160 people. The results show that the instrument has good internal consistency (α= 0.896), able to distinguish individuals in groups based on discrimination items, and valid in measuring constructs (Model Fit CFI = 0.922; GFI = 0.901; SRMR = 0.055, and have a good factor loading). Thus, Indonesian version of DREEM short-form is a valid and reliable tool for use in research in the field of education in a wider range of institutions.Indonesian: Lingkungan pembelajaran sangatlah penting untuk mendukung prestasi mahasiswa. Pada masa pandemi COVID-19 hingga transisi new normal, mahasiswa dihadapkan dengan lingkungan pembelajaran yang berubah-ubah, dimulai dari daring, hybrid, hingga full luring. Dundee Ready Education Environment Measure (DREEM) merupakan instrumen yang mengukur persepsi mahasiswa terhadap lingkungan pembelajarannya dalam institusi medis yang dikembangkan oleh Roff, et.al. (1997). Awalnya DREEM berjumlah 50-item untuk mengukur lima domain, kemudian dikembangkan dalam versi singkat (short-form) 12-item oleh Jeyashree, Shewade, dan Kathrivel (2018). Selama ini belum ada alat ukur dalam Bahasa Indonesia untuk DREEM short version 12-item untuk institusi di luar medis. Maka penelitian ini bertujuan untuk membuat adaptasi dan validasi alat ukur DREEM Short-Form 12-item untuk institusi yang lebih luas. Populasi dari pengujian alat ukur ini adalah mahasiswa di Indonesia dengan sampel sebanyak 160 orang. Hasilnya menunjukkan bahwa alat ukur yang telah diadaptasi memiliki konsistensi internal yang baik (reliabilitas α= 0.896), mampu membedakan individu dalam kelompok berdasarkan item discrimination, dan valid dalam mengukur konstruk (Model Fit CFI = 0,922; GFI = 0,901; SRMR = 0,055, dan memiliki muatan faktor yang baik). Dengan begitu, DREEM-12 Bahasa Indonesia merupakan alat ukur yang valid dan reliabel untuk digunakan dalam penelitian di bidang pendidikan pada setting yang lebih luas.
Kinetics, Equilibrium and Thermodynamic Studies on Removal of Oleic Acid from Sunflower Oil onto Amberlyst A21
Authors: Ilgen Oguzhan , Tümkor Elif 
Published: July 2023

Amberlyst A21 was used for the oleic acid adsorption from sunflower oil (SFO). The impacts of parameters such as contact time, temperature, and mass ratio of adsorbent on oleic acid adsorption were studied. The characterization of Amberlyst A21 before and after adsorption was performed by using Fourier transform infrared spectrometer (FTIR) and scanning electron microscope (SEM). The adsorption reached equilibrium 480 minutes later. The increase in temperature and the amount of adsorbent caused an increase in the amount of adsorbed oleic acid. The adsorption kinetics, isotherms, and thermodynamics were studied. The pseudo-first order kinetics well described the adsorption for all studied temperatures. The Langmuir, Freundlich, and Dubinin−Radushkevich isotherms and thermodynamic analysis were investigated at equilibrium. The suitability of the Langmuir and Freundlich isotherms indicated that the adsorption takes place under monolayer and heterogeneous surfaces. Thermodynamical results showed that adsorption occurs spontaneously and endothermic.
Dose- and application route-dependent effects of betahistine on behavioral recovery and neuroplasticity after acute unilateral labyrinthectomy in rats
Authors: Antons Melissa , Lindner Magdalena , Eilles Eva , Günther Lisa , Delker Astrid , Branner Christina , Krämer Anja , Beck Roswitha , Oos Rosel , Wuehr Max , Ziegler Sibylle , Strupp Michael , Zwergal Andreas 
Published: July 2023

IntroductionBetahistine is widely used for the treatment of various vestibular disorders. However, the approved oral administration route and maximum daily dose are evidently not effective in clinical trials, possibly due to a major first-pass metabolism by monoamine oxidases (MAOs). The current study aimed to test different application routes (i.v./s.c./p.o.), doses, and concurrent medication (with the MAO-B inhibitor selegiline) for their effects on behavioral recovery and cerebral target engagement following unilateral labyrinthectomy (UL) in rats.MethodsSixty rats were subjected to UL by transtympanic injection of bupivacaine/arsanilic acid and assigned to five treatment groups: i.v. low-dose betahistine (1 mg/kg bid), i.v. high-dose betahistine (10 mg/kg bid), p.o. betahistine (1 mg/kg bid)/selegiline (1 mg/kg once daily), s.c. betahistine (continuous release of 4.8 mg/day), and i.v. normal saline bid (sham treatment; days 1–3 post-UL), respectively. Behavioral testing of postural asymmetry, nystagmus, and mobility in an open field was performed seven times until day 30 post-UL and paralleled by sequential cerebral [18F]-FDG-μPET measurements.ResultsThe therapeutic effects of betahistine after UL differed in extent and time course and were dependent on the dose, application route, and selegiline co-medication: Postural asymmetry was significantly reduced on 2–3 days post-UL by i.v. high-dose and s.c. betahistine only. No changes were observed in the intensity of nystagmus across groups. When compared to sham treatment, movement distance in the open field increased up to 5-fold from 2 to 30 days post-UL in the s.c., i.v. high-dose, and p.o. betahistine/selegiline groups. [18F]-FDG-μPET showed a dose-dependent rCGM increase in the ipsilesional vestibular nucleus until day 3 post-UL for i.v. high- vs. low-dose betahistine and sham treatment, as well as for p.o. betahistine/selegiline and s.c. betahistine vs. sham treatment. From 1 to 30 days post-UL, rCGM increased in the thalamus bilaterally for i.v. high-dose betahistine, s.c. betahistine, and p.o. betahistine/selegiline vs. saline treatment.DiscussionBetahistine has the potential to augment the recovery of dynamic deficits after UL if the administration protocol is optimized toward higher effective plasma levels. This may be achieved by higher doses, inhibition of MAO-based metabolism, or a parenteral route. In vivo imaging suggests a drug-target engagement in central vestibular networks.
Estimation of minimal detectable change in the 10-meter walking test for patients with stroke: a study stratified by gait speed
Authors: Hosoi Yuichiro , Kamimoto Takayuki , Sakai Katsuya , Yamada Masanari , Kawakami Michiyuki 
Published: July 2023

ObjectiveThis study aimed to classify and calculate the minimal detectable changes (MDC) in gait time and gait speed in a 10-meter walking test (10MWT) in patients with stroke classified according to their gait speed.MethodsThe participants were 84 patients with stroke. Their gait times were measured twice each at their comfortable gait speed (CGS) and maximum gait speed (MGS) on a 10-meter straight track, and gait speed was calculated using gait time. Participants were assigned to three speed groups based on their CGS: low-speed (&lt;0.4 m/s; n = 19); moderate-speed (0.4–0.8 m/s; n = 29); and high-speed (&gt;0.8 m/s; n = 36). For each group, first and second retest reliability and MDC of CGS and MGS were calculated using gait time and gait speed in the 10MWT.ResultsMDCs in the 10MWT at CGS were: low-speed group, gait time 5.25 s, gait speed 0.05 m/s; moderate-speed group, gait time 2.83 s, gait speed 0.11 m/s; and high-speed group, gait time 1.58 s, gait speed 0.21 m/s. MDCs in the 10MWT at MGS were: low-speed group, gait time 7.26 s, gait speed 0.04 m/s; moderate-speed group, gait time 2.48 s, gait speed 0.12 m/s; and high-speed group, gait time 1.28 s, gait speed 0.19 m/s.ConclusionSince the MDC of gait speed and gait time differ depending on the participant’s gait speed, it is necessary to interpret the results according to the participant’s gait speed when judging the effectiveness of therapeutic interventions.
Sex differences in intuitive eating and its relationship with body mass index among adults aged 18–40 years in Saudi Arabia: a cross-sectional study
Authors: Albajri Eram , Naseeb Manal 
Published: July 2023

IntroductionIntuitive eating (IE) is eating without judgment, relying only on physiological hunger and satiety. Sex differences in IE have been reported; however, none of the studies have explicitly examined IE and its relationship with body mass index (BMI) in the Saudi Arabian population. Thus, this study aimed to investigate sex differences in IE and its relationship with BMI in the Saudi population.Subjects/methodsA cross-sectional online survey of 360 participants (18 years or older) with self-reported weight and height was conducted. IE was measured using the Intuitive Eating Scale-2 (IES-2). Separate multiple linear regression analyses were conducted to determine if total IE and its subscale scores differed across sexes. It was also conducted to assess the relationship between IE and BMI across sexes.ResultsWomen had higher total IE score, eating for physical rather than emotional reasons (EPR), and body-food choice congruence (BFCC) scores compared to men (p = 0.013, p = 0.01, p &lt;0.001, respectively). The analysis showed a significant negative association between total IE, BFCC, EPR scores, and BMI in women compared to men (p = 0.023, p = 0.01, p = 0.003, respectively).ConclusionThe data on the sex differences in IE and its subscales and their different association with BMI encourage tailing nutrition-related recommendations in the context of intuitive eating based on sexes. Future studies are needed to explore how intuitive eating functions differently in women compared to men and explore the causal relationship between IE and BMI in this population.
A cuproptosis-related lncRNA signature predicts the prognosis and immune cell status in head and neck squamous cell carcinoma
Authors: Zheng Xiwang , Zheng Defei , Zhang Chunming , Guo Huina , Zhang Yuliang , Xue Xuting , Shi Zhaohui , Zhang Xiangmin , Zeng Xianhai , Wu Yongyan , Gao Wei 
Published: July 2023

IntroductionThe incidence of head and neck squamous cell carcinoma (HNSCC), one of the most prevalent tumors, is increasing rapidly worldwide. Cuproptosis, as a new copper-dependent cell death form, was proposed recently. However, the prognosis value and immune effects of cuproptosis-related lncRNAs (CRLs) have not yet been elucidated in HNSCC.MethodsIn the current study, the expression pattern, differential profile, clinical correlation, DNA methylation, functional enrichment, univariate prognosis factor, and the immune effects of CRLs were analyzed. A four-CRL signature was constructed using the least absolute shrinkage and selection operator (LASSO) algorithm.ResultsResults showed that 20 CRLs had significant effects on the stage progression of HNSCC. Sixteen CRLs were tightly correlated with the overall survival (OS) of HNSCC patients. Particularly, lnc-FGF3-4 as a single risk factor was upregulated in HNSCC tissues and negatively impacted the prognosis of HNSCC. DNA methylation probes of cg02278768 (MIR9-3HG), cg07312099 (ASAH1-AS1), and cg16867777 (TIAM1-AS1) were also correlated with the prognosis of HNSCC. The four-CRL signature that included MAP4K3-DT, lnc-TCEA3-1, MIR9-3HG, and CDKN2A-DT had a significantly negative effect on the activation of T cells follicular helper and OS probability of HNSCC. Functional analysis revealed that cell cycle, DNA replication, and p53 signal pathways were enriched.DiscussionA novel CRL-related signature has the potential of prognosis prediction in HNSCC. Targeting CRLs may be a promising therapeutic strategy for HNSCC.
Non-selective beta-blockers and the incidence of hepatocellular carcinoma in patients with cirrhosis: a meta-analysis
Authors: He Xinyi , Zhao Zimo , Jiang Xi , Sun Yan 
Published: July 2023

Background: Hepatocellular carcinoma (HCC) is a serious complication of cirrhosis. Currently, non-selective beta-blockers (NSBBs) are commonly used to treat portal hypertension in patients with cirrhosis. The latest research shows that NSBBs can induce apoptosis and S-phase arrest in liver cancer cells and inhibit the development of hepatic vascular endothelial cells, which may be effective in preventing HCC in cirrhosis patients.Aim: To determine the relationship between different NSBBs and HCC incidence in patients with cirrhosis.Methods: We searched the Cochrane database, MEDLINE, EMBASE, PubMed, and Web of Science. Cohort studies, case‒control studies, and randomized controlled trials were included if they involved cirrhosis patients who were divided into an experimental group using NSBBs and a control group with any intervention. Based on heterogeneity, we calculated odds ratio (OR) and 95% confidence interval (CI) using random-effect models. We also conducted subgroup analysis to explore the source of heterogeneity. Sensitivity analysis and publication bias detection were performed.Results: A total of 47 studies included 38 reporting HCC incidence, 26 reporting HCC-related mortality, and 39 reporting overall mortality. The HCC incidence between the experimental group and the control group was OR = 0.87 (0.69 and 1.10), p = 0.000, and I2 = 81.8%. There was no significant association between propranolol (OR = 0.94 and 95%CI 0.62–1.44) or timolol (OR = 1.32 and 95%CI 0.44–3.95) and HCC incidence, while the risk of HCC decreased by 26% and 38% with nadolol (OR = 0.74 and 95%CI 0.64–0.86) and carvedilol (OR = 0.62 and 95%CI 0.52–0.74), respectively.Conclusion: Different types of NSBB have different effects on the incidence of patients with cirrhosis of the liver, where nadolol and carvedilol can reduce the risk. Also, the effect of NSBBs may vary in ethnicity. Propranolol can reduce HCC incidence in Europe and America.Systematic Review Registration: identifier https://CRD42023434175, https://www.crd.york.ac.uk/PROSPERO/.
Cavity ring-down spectroscopy with a laser frequency stabilized and locked to a reference target gas absorption for drift-free accurate gas sensing measurements
Authors: Liu Ying , He Yabai , Hu Mai , Chen Bing , Xu Zhenyu , Yao Lu , Wang Xingping , Kan Ruifeng 
Published: July 2023

A new gas sensor system with fast response and ultra-high sensitivity has been developed based on a combination of frequency modulation spectroscopy (FMS) and cavity ring-down spectroscopy (CRDS). The system consisted of two distributed feedback laser diodes (DFB-LDs) emitting at frequencies 6251.761 cm-1 (Laser-1) and 6257.762 cm-1 (Laser-2), respectively. A portion of Laser-1’s output was used by a frequency modulation spectroscopy technique to lock its frequency precisely at a CO2 absorption peak, while the rest of its output was coupled to an optical ring-down cavity, together with the Laser-2 output. The Laser-2 operated at a non-absorbing frequency for real-time correction of any baseline ring-down time drift caused by environmental changes (e.g., temperature, pressure). Laser frequency stabilization achieved a 5-fold improvement in CRDS detection sensitivity. This new system was able to make measurements at a data rate of 9 Hz. Based on Allan deviation analysis, the absorbance detection limit of the system was 4.4 × 10−11 cm-1 at an optimum averaging time of ∼5 s, whereas the time-normalized sensitivity at 1 s was 7.3 × 10−11 cm-1/Hz1/2. Measurements of atmospheric CO2 mole fraction were conducted and demonstrated its good performance and reliability. This sensor will be particularly suitable for making drift-free measurements over long periods, in the fields of environmental and industrial gas sensing.