bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lower urinary tract dysfunction in cases of anorectal malformations
Authors: Saxena Gaurav 
Published: May 2023

Association of genitourinary anomalies in patients with ano-rectal malformations (ARM) is well known and its incidence is reported to be 30 -50%. Many of these anomalies either have less number of functioning renal units or have conditions with risk of continuous damage to renal units, increasing the risk of developing End stage renal disease (ESRD) in adolescence or adulthood. Although frequently described as associated malformations but few of these entities like Vesico ureteric reflux (VUR) could be the result of lower urinary tract dysfunctions.: To study incidence and spectrum of Lower urinary tract dysfunction in toilet trained patients of ARM. To find whether LUTD is the cause of worsening of VUR/HUN/ renal functions in patients with ARM.

2 years (October 2018 to 30 September 2020): Department of Paediatric surgery, Chacha Nehru Bal Chikitsalaya, Geeta Colony Delhi Prospective observational study. : Forty-two patients of ARM, meeting all inclusion criteria were enrolled in the study. All the following criteria were checked for enrolment of patient in the study. 1. Patients of all categories of anorectal malformations who were toilet trained; 2. Age more than 4 years; 3. Completed set of investigations planned for diagnosis of LUTD. 4. Consented to participate in the study and for follow up as and when required.Central cause of neurological deficits.A total of 125 patients who underwent PSARP during our study period. However only 42 patients met the inclusion criteria and got their work up completed for urological problems. 1.LUTD and renal failure can be seen even in absence of spinal malformations in patients with ARM; 2. Severity of LUTD in absence of neurological involvement changes with time; 3. Thorough history and clinical evaluation may provide important clues in suspecting presence of occult LUTD.
The US Congress 118th: a Gender Portrait
Authors: Shvedova Nadezhda 
Published: May 2023

Senator Patty Murray of Washington was solemnly sworn in by Vice President Kamala Harris in the Old Senate Hall on Capitol Hill in Washington on January 3, 2023, in front of Murray&apos;s husband, Rob Murray. She became the first woman to temporarily become President of the Senate. The episode is like a historical symbol of the conquest of heights of power by American women in the first quarter of the 21st century: a duet of American women perform a &quot;routine&quot; action in the procedure for transferring power.
The American press, not without reason, interprets the results of the election of women to various levels during the 2022 midterm elections as “new records”.
The 118th US Congress (2022-2024) has a record number of women. The point of view that it was the issue of abortion that helped &quot;limit the losses of the Democrats&quot; in the last election cycle was widely accepted among specialists. The Supreme Court&apos;s dismissal of Roe v. Wade has placed abortion at the center of the election debate, along with the economy, inflation and immigration. The election took place amid a global financial downturn and a notable rise in the cost of living in the United States. In addition, they are the first since the June 2022 Supreme Court ruling overturned the 1973 Roe v. Wade decision.
The Democrats retained control of the Senate. The Republican Party won a majority in the House of Representatives. In thinking about expanding the political power and representation of American women, it is necessary to consider the barriers to women&apos;s retention in office and how to remove those barriers, recognizing the full range of diversity among them—and, in particular, the diversity of their political experiences and opportunities—in political institutions.
The gubernatorial level of power demonstrates the same trend. Nearly a quarter of all US governors are women. Moreover, there are twice as many women democrats among them. In total, 12 American women occupy this level of office: 8 of them are Democrats, 4 - Republicans.
Evaluation of Potential Drug-Drug Interactions in Hospitalized Pediatric Patients with Bronchitis Diagnosis: A Retrospective Study
Authors: Taner Neda , Eskitoğlu Müferiye , Şirin Betül 
Published: May 2023

Background: Acute bronchitis is one of the most common infectious diseases in children and a major cause of hospital admissions. Treatment of acute bronchitis is usually symptomatic, analgesics and antipyretics are often used. The simultaneous intake of drugs brings pharmacological interactions with it. These interactions are important for the success of the treatment. The aim of our investigation is to determine the prevalence and severity of possible drug interactions; draw attention to drug interactions in children and adolescents.

Methods: This study was conducted on 99 patients, 48 ​​males and 51 females, with bronchitis hospitalized between 2019 and 2021 in Rize, Turkey. Patient records were retrospectively evaluated, and drug interactions were determined using database Medscape data by clinical pharmacists. Data was analyzed by SPSS 15.0v. statistical program p<0.05 was considered significant. The severity of the interactions was assessed as an alternative to serious use, close monitoring and minor interactions.
Results: In this study, it was found that the mean age of the patients was 5.17 ± 2.31 years. A total of 69 drug-drug interactions were identified, most of which (63.6%) were identified on the ‘Close Monitor', and the interaction rate at the 'Serious Use Alternative' level was found to be 16.2%. There was no interaction in some patients in this study; but some patients experienced up to 4 interactions.
Conclusion: Healthcare professionals should be more cautious about polypharmacy and more aware of the rational use of drugs. By raising awareness of drug interactions among healthcare professionals, drug interactions can be minimized.
Worldwide Efficiency of Bioremediation Techniques for Organic Pollutants in Soil: A Brief Review
Authors: Akhtar Sana , Mohsin Ayesha , Riaz Aiman , Mohsin Farhan 
Published: May 2023

Soil pollution is a major human and environmental issue. Among the several components of soil degradation, organic contaminant in soil is regarded as a significant factor that causes considerable damage to the environment along with several health dangers to humans. Polychlorinated biphenyls, polycyclic aromatic hydrocarbons, polychlorinated dibenzofurans, poly-brominated biphenyls, organic fuels particularly gasoline and diesel, herbicides, insecticides (carbamate and organophosphorus) are by far the most common forms of organic pollutants identified in soils. The employment of living organisms such as microorganisms and plants in bioremediation technology reduces/degrades, eliminates, and transforms pollutants found in soils, sediments, and water. This review examine and critically view the efficiency of bioremediation techniques for the polluted sites. The most common bioremediation technologies for the treatment of organic pollutants are bioventing, bio-sparging, bio-slurping, bio-augmentation, phytoremediation, bio-immobilization, bio-sorption, composting, land farming, aerobic degradation, co-metabolic and natural attenuation. The efficiency of these techniques depends on the pH, type of soil, level of oxygen, any other electron acceptors, temperature, and the nutrients. Selection of the treatment process depends upon the type of pollutant, concentration of the contaminant, site and source of pollution. All the treatment techniques are not good for all type of pollutants. Cost-effective techniques are mostly used worldwide as they have more public acceptance. Pump and treat methods were mostly used in Past but due to its non-reliability and excessive cost, these techniques are no longer in use.
Keywords: Bioremediation Techniques; Soil Pollution; Organic Pollutants; Efficiency, Environmental Contamination

Copyright (c) 2023 Geosfera Indonesia and Department of Geography Education, University of Jember
This work is licensed under a Creative Commons Attribution-Share A like 4.0 International License
MITIGATION VOLTAGE SAG USING DVR WITH HYSTERESIS-ANN CONTROL ON DISTRIBUTION SYSTEM PUJON FEEDER LINE
Authors: Suryo Arief Trisno Eko 
Published: May 2023

This paper discusses the mitigation of voltage sag in distribution systems. Voltage sag often occurs due to a single line-to-ground short circuit fault. The fault has a major impact on load damage in the Pujon feeder line. Voltage sag can be mitigated by using Dynamic Voltage Restorer (DVR). DVR is one type of custom device that is effective in overcoming voltage sag. DVR requires control in regulating voltage recovery on the Pujon line. This research proposes DVR control using Hysteresis combined with ANN to mitigate voltage sag on Pujon line. Simulation results show that the Hysteresis-ANN control is able to recover the load voltage in phase R on average by 97% due to voltage sag that occurs on the Pujon feeder line.
The Concept of Malakah Ibn Khaldun in the Context of Teaching that Applies High Order Thinking Skills (HOTS)
Authors: Othman Mohd Syaubari Bin , Hoshan Hasrul , Yusof Abu Bakat , Abdullah Zaini , Mohamed Abd Talib 
Published: May 2023

ABSTRACT:
The high order thinking skills (HOTS) is a transformation in the education system in Malaysia this century in line with the implementation of the Malaysia Education Blueprint 2013-2025. The practice of implementing HOTS has outperformed the entire subject content concept by focusing on several HOTS theories in particular the Bloom and Taksnomi Marzano taxonomy. However, for the Islamic Education subjects based on the Quran and As-Sunnah, the implementation of this HOTS element needs to be translated through the basis of the Islamic Education Philosophy that puts the perfectional of the intellectual education as the main thrust in driving this thinking thinking culture. The emergence of figures such as Ibn Khaldun, which speaks thoroughly of the mind-based concept of Malakah, has sparked diversity in the perspective of the understanding of HOTS understanding. For this reason, this study uses the analysis process by analyzing the literature by examining the contents of a synonymity or summarized in the meaning of the poor concept of Ibn Khladun in the context of the teaching of Islamic education subjects. The results of this study resulted in four basic concepts in the application of HOTS through the use of Malakah combined with the use of aql tamyizi, aql tajribi, aqal nazori and insaniyah fact. In general, the implementation of Islamic Education PdP which implements HOTS should focus on the process and philosophy of teaching that Ibn Khaldun has established to ensure that students' understanding, appreciation and practice assesses the requirements set out on the basis of the Islamic Education Philosophy.
Exploration study of indigenous civet (Paradoxorus hermaphroditus) bacteria: isolates characterization and molecular identification
Authors: Muzaifa Murna , Abubakar Yusya , Febriani Febriani , Abubakar Amhar 
Published: May 2023

Biochemistry of civet coffee fermentation in the digestive tract of civets until now is not fully known. This study aims to isolation, characterization and identification of bacteria molecularly from the civet's digestive tract. Analysis of bacteria begins with the civet surgery to obtain fluid from three parts of the civet's digestive tract. Isolation of bacteria conducted by pour plate method using nutrient agar media. Single and different colonies (shape, colour, margin, elevation, size) were separated and purified by streaking method. The pure isolate was further characterized biochemically. The biochemical characteristics of the bacteria observed were Gram staining, catalase, protease and pectinase activity. Identification of the bacteria was carried out molecularly by identifying the 16S rRNA gene. The results of molecular identification showed that the bacteria from the civet were identified as Alcaligenes faecalis strain LHW 1749, Ochrobactrum anthropi, Stenotrophomonas sp. 262 and Bacillus sp.
Oxidative stress, DNA damage, and gene expression in earthworms (Eisenia fetida) exposure to ethiprole
Authors: zhou min , Zhang Caixia , Wang Fuhao , Hao Peipei , Liu Ziqi , Cheng Youpu 
Published: May 2023

Abstract

To evaluate the potential ecotoxicity of ethiprole and early warning to earthworms (Eisenia fetida), different concentrations (0, 416, 625, and 1 000 mg kg− 1) of ethiprole were added to artificial soil. The key bioindicators were measured and screened at 3, 7, 14, 21, and 28 d. The results show that the activity of catalase (CAT) was inhibited for all treatments during the whole exposure period. Besides, the olive tail moment (OTM) value increased gradually as the concentration got higher, which exhibited a dose-time-dependent relationship. Superoxide dismutase (SOD) gene reaching the maximum on the 7th d. Mitochondrial large ribosomal subunit (l-rRNA) gene was always in a down-regulated state as the concentration increased. Our results show that different concentrations of ethiprole induced certain oxidative stress, DNA damage, and genotoxicity in earthworms. The CAT activity, OTM, and SOD gene could be the most sensitive biomarkers to monitor the toxicity of ethiprole in the soil.
Safety and Efficacy of Intra-arterial Mesenchymal Stem Cell Therapy in an Endovascular Canine Model of Ischemic Stroke
Authors: Yavagal Dileep , Thakkar Roshni , Guada Luis , Watanabe Mitsuyoshi , Bates Karen , Nishimura Kengo , Saini Vasu , Raval Ami , Bhattacharya Pallab , Pedraza Diego Ojeda , Torress Amanda , Garza Phillip , Ramdas Kevin , Sidani Charif , khan Aisha , Rundek Tatjana , Hare Joshua 
Published: May 2023

Abstract
The safety and benefit of intra-arterial (IA) allogeneic Mesenchymal Stem Cells (MSCs) administered within 1-2 days of stroke in rodent models hold transformative potential for treating acute ischemic stroke (AIS). However, the lack of large animal studies of this approach is a significant gap in predicting success in human clinical trials, given the small size of the rodent brain and arterial vasculature and the lower white-to-gray-matter ratio. Another critical gap is the inability to extrapolate IA MSC dose ranges of MSCs and their therapeutic index from rodent models in a predictable manner. Here we employed an endovascular canine stroke model to evaluate the safety and efficacy of escalating IA doses of allogeneic MSCs at 10, and 40 million (m), and 80m MSCs versus phosphate buffer saline (PBS) controls. The IA MSC group showed safety on the primary endpoints of no worsening of neurological deficit and no new ischemia on imaging up to 40m dose. There was a significantly higher improvement in the treatment group in primary efficacy endpoints of neurological function and reduction in infarct volume on MRI and on the secondary endpoint of recovery of corticospinal tract caliber and fractional anisotropy on DTI compared to controls at 15- and 30-days post-stroke. A significant increase in neuronal survival was also seen in the IA MSC group vs the PBS control. Upon further dose escalation to 80m, there was worsened neurological score and worsened infarct at 4 days post-injection. Thus this study shows the safety and efficacy of IA MSCs over a dose range of 10-40m in a large animal model and its therapeutic index. In conclusion, these findings suggest a high translational success of IA allogeneic MSCs for AIS and provide critical information for the design of future clinical trials.
Sensibility pulp testing in Multiple Sclerosis, considering disease duration, sensory/motor symptoms, age and gender: A cross-sectional study
Authors: Owlia Fatemeh , Noori Fereshteh , zarchi Marzieh Abutorabi , Kazemipoor Maryam 
Published: May 2023

Abstract
Introduction: The evaluation of the pulpal threshold to sensibility tests, as a side effect of possible neuropathy in Multiple Sclerosis (MS) patients, is a novel issue. This research extended prior work on evaluation of the response to electric pulp testing in multiple sclerosis patients without a history of trigeminal neuralgia. This survey has made an attempt to investigate the relationship between some sensibility pulp tests thresholds and the disease duration in MS patients.Materials and Methods: One hundred twenty-four maxillary central incisors belonging to relapsing-remitting MS patients were encompassed in this survey. The patients were unified, the age range was 18–50 years old, suffered from relapsing-remitting MS, and no history of trigeminal neuralgia. Electric and cold pulp sensibility tests were performed for all teeth. Electric pulp testing (EPT) results were recorded based on the pulp tester's grade that evoked a response. Data were analyzed with paired T-test, Fisher exact test, and spearman correlation. The significance level was set as p < 0.05.Results: Based on these findings, the mean value of response to EPT was 2.69 ± 1.17 and the time of the response to the cold test was 2.61 ± 1.03 seconds, respectively. Males and the older group significantly responded to a cold test in a longer time. No significant difference was recognized between the pulpal response to EPT and the cold test in patients with and without sensory-motor involvement (p > 0.05). According to spearman analysis, there was a significant positive correlation between electrical pulp threshold and the duration time to respond to the cold test (P = 0.025, r = 0.2).Conclusions: The application of the pulpal sensibility test in MS patients would lend itself well for use by clinicians. Patients with longer disease duration bared significantly higher threshold for EPT and the cold test in their maxillary central incisors.
Supporting people and nature across neighboring nations with land-sea planning at multiple scales
Authors: Delevaux Jade , Silver Jessica , Winder Samantha , Bood Nadia , Chevez Luis , Velásquez Pilar , Vela Alejandra Calzada Vázquez , Barlett Ryan , Porta Maria Amalia , Wolny Stacie , Bailey Allison , McField Melanie , Muñiz-Castillo Aarón , Arkema Katie 
Published: May 2023

Abstract
Deforestation impacts the benefits coral reefs provide to coastal communities in multiple ways. Yet, connections between terrestrial and marine ecosystems are generally assessed at a single scale and from an ecological perspective alone. This limits understanding of societal outcomes and the distributional effects of watershed interventions. We employ linked land-sea ecosystem service models in the Mesoamerican Reef region to explore how watershed management (restoration, protection, and sustainable agriculture) at regional and country scales influences where to prioritize actions and the delivery of coastal and marine benefits. With a regional perspective, interventions are prioritized in larger transboundary watersheds, resulting in more sediment retention and healthier coral reefs for neighboring nations. At the country scale, non-transboundary, often smaller, watersheds are targeted, leading to decreased coastal risk, and increased tourism and fisheries benefits for each nation individually. Our findings highlight the effect of scale on social and ecological outcomes across and within nations. We identify win-win strategies that can improve forests and coral health while generating increased benefits to coastal communities.
Unveiling Scientific Articles from Paper Mills with Provenance Analysis
Authors: Cardenuto João Phillipe , Moreira Daniel , Rocha Anderson 
Published: May 2023

Abstract

The increasing prevalence of fake publications created by paper mills poses a significant challenge to maintaining scientific integrity. While integrity analysts typically rely on textual and visual clues to identify fake articles, determining which papers merit further investigation can be akin to searching for a needle in a haystack, as these fake publications have non-related authors and are published on non-related venues. To address this challenge, we developed a new methodology for provenance analysis, which automatically tracks and groups suspicious figures and documents. Our approach groups manuscripts from the same paper mill by analyzing their figures and identifying duplicated and manipulated regions. These regions are linked and organized in a provenance graph, providing evidence of systematic production. We tested our solution on a paper mill dataset of hundreds of documents and also on a larger version of the dataset that deliberately included thousands of documents intentionally selected to distract our method. Our approach successfully identified and linked systematically produced articles on both datasets by pinpointing the figures they reused and manipulated from one another. The technique herein proposed offers a promising solution to identify fraudulent manuscripts, and it could be a valuable tool for supporting scientific integrity. All datasets, annotations, trained models, and implementations from this research are freely available at https://github.com/phillipecardenuto/upm.
Preparation of bacterial cellulose-g-poly(methyl methacrylate) porous sheet for PLA lamination
Authors: Phetchara Thapani , Kampeerapappun Piyaporn , Srikul Kawee 
Published: May 2023

Abstract
Bacterial cellulose-g-poly(methyl methacrylate) (BC-g-PMMA) porous sheet was prepared by grafting colloidal BC with PMMA using K2S2O8 as initiator. BC-g-PMMA representatives were prepared for PLA/BC laminates. The grafting was carried out using BC: MMA monomer ratios of 1:1 and 1:5 using K2S2O8 as initiator at 70 ºC for 4 h. Oil-in-water BC-g-PMMA colloid was cast and oven-dried into porous sheet. FTIR spectrum of BC-g-PMMA (BC1:5) showed strong intensity peak at 1725 cm-1, corresponding to PMMA absorption band. SEM images showed that BC1:5 exhibited open porous structure due to the effect of water as the physical blowing agent. TGA and DSC were performed. The results showed that BC-g-PMMA (BC1:5) exhibited stepwise degradation and Tg at 117 °C which confirmed the successful grafting reaction. Then, PLA/BC-g-PMMA/PLA laminate sheets were prepared using compression machine and characterized by SEM to confirm good adhesion at the interface. Mechanical, thermal, and biodegradable properties were evaluated. Interestingly, the laminate having porous BC sheet exhibited good thermal stability which is suitable for high temperature application.
Urban-rural disparities in hypertension prevalence and its influencing factors among Chinese middle-aged and older adults: Results from the China Health and Retirement Longitudinal Study (CHARLS), 2018
Authors: Yin Minghui , Liu Caiping 
Published: May 2023

Abstract
The urban-rural disparity in the prevalence of hypertension among middle-aged and older in China remains unclear. We used the data collected from the fourth wave (2018) of the China Health and Retirement Longitudinal Study (CHARLS) (n = 12,245) and analyzed using probit regression. Firstly, the prevalence of diagnosed, measured, total and undiagnosed hypertension is higher in urban areas than in rural areas (25.9% vs. 21.6%, 35.2% vs. 31.2%, 46.1% vs. 40.7%, and 20.2% vs. 19.1%, respectively). Past smokers and current smokers, compared with non-smokers, had a higher probability of total hypertension in rural areas (12.5% and 4.9%, respectively), and the difference was significant (p < 0.01). Compared with Sedentary exercisers, regular exercisers had a lower probability of total hypertension in rural areas than in urban areas (41.5% and 38.3%, respectively), and the difference was significant (p < 0.01). Our study shows that, Firstly, smoking is a significant risk factor for the urban-rural disparity of hypertension, which is significantly worse in rural areas. Secondly, though regular exercise helps prevent hypertension in both areas, urban residents need to exercise more.