bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ultra-efficient generation of time-energy entangled photon pairs in an InGaP photonic crystal cavity
Authors: Chopin Alexandre , Barone Andrea , Ghorbel Inès , Combrié Sylvain , Bajoni Daniele , Raineri Fabrice , Galli Matteo , De Rossi Alfredo 
Published: April 2023

AbstractThe typical approaches to generate heralded single photons rely on parametric processes, with the advantage of generating highly entangled states at the price of a random pair emission. To overcome this limit, degenerate spontaneous Four-Wave-Mixing is a reliable technique which combines two pump photons into a pair of signal and idler photons via Kerr nonlinear optical effect. By exploiting the intrinsic small confinement volume and thermally tuning the resonances of a 20 μm-long Photonic Crystal cavity, we efficiently generate time-energy entangled photon pairs and heralded single photons at a large maximum on-chip rate of 22 MHz, using 36 μW of pump power. We measure time-energy entanglement with net visibility up to 96.6 % using 1 second integration time constant. Our measurements demonstrate the viability of Photonic Crystal cavities to act as an alternative and efficient photon pair source for quantum photonics.
Thermochronometry constraints on south West Greenland passive continental margin development
Authors: Danišík Martin , Kirkland Christopher L. 
Published: April 2023

AbstractPassive continental margins (PCMs) represent the interface between the marine and terrestrial realms. However, topographic evolution of PCMs is often difficult to decipher due to paucity of the preserved geological record. Here, we report uranium-thorium-helium ((U-Th)/He) analysis of the Precambrian crystalline basement from southern West Greenland that help constrain the process of rifting between Greenland and North America and contributes to the debate about the West Greenland PCM development. The majority of zircon (U-Th)/He dates (220-580 Ma) imply several kilometres of burial of the basement by Paleozoic (and potentially Mesozoic) sediments. Apatite (U-Th)/He dates (80-230 Ma) record thermal processes associated with extensional tectonism starting in the Late Triassic and passive margin formation in the Early Cretaceous. Our data provide no evidence of thermal activity during Cenozoic times, suggesting that the thermal effects of Paleogene rifting and break-up were negligible and the magnitude of Cenozoic erosion was <3.5 km in the study area.
Examining equity in access and utilization of a freely available meditation app
Authors: Jiwani Zishan , Tatar Raquel , Dahl Cortland J. , Wilson-Mendenhall Christine D. , Hirshberg Matthew J. , Davidson Richard J. , Goldberg Simon B. 
Published: April 2023

AbstractDigital interventions have the potential to alleviate mental health disparities for marginalized and minoritized communities. The current study examined whether disparities in access and utilization of meditation in the United States (US) were reduced for a freely available meditation app. We analyzed demographic and usage data from US-based users of the Healthy Minds Program (HMP; N = 66,482) between October 2019 and July 2022. College education was associated with a greater likelihood of accessing (65.0% of users vs. 32.9% of the US population) and continuing to utilize the app (β = 0.11–0.17). Conversely, identifying as African American was associated lower likelihood of accessing (5.3% vs. 13.4% of the US population) and continuing to utilize the app (β = −0.02–0.03). African Americans were more likely to access content from an African American meditation teacher, but this did not appear to increase utilization. Additional efforts are warranted to identify factors that might reduce disparities.
Speech Entrainment in Adolescent Conversations: A Developmental Perspective
Authors: Wynn Camille J. , Barrett Tyson S. , Berisha Visar , Liss Julie M. , Borrie Stephanie A. 
Published: April 2023

Purpose:
Defined as the similarity of speech behaviors between interlocutors, speech entrainment plays an important role in successful adult conversations. According to theoretical models of entrainment and research on motoric, cognitive, and social developmental milestones, the ability to entrain should develop throughout adolescence. However, little is known about the specific developmental trajectory or the role of speech entrainment in conversational outcomes of this age group. The purpose of this study is to characterize speech entrainment patterns in the conversations of neurotypical early adolescents.

Method:
This study utilized a corpus of 96 task-based conversations between adolescents between the ages of 9 and 14 years and a comparison corpus of 32 task-based conversations between adults. For each conversational turn, two speech entrainment scores were calculated for 429 acoustic features across rhythmic, articulatory, and phonatory dimensions. Predictive modeling was used to evaluate the degree of entrainment and relationship between entrainment and two metrics of conversational success.

Results:
Speech entrainment increased throughout early adolescence but did not reach the level exhibited in conversations between adults. Additionally, speech entrainment was predictive of both conversational quality and conversational efficiency. Furthermore, models that included all acoustic features and both entrainment types performed better than models that only included individual acoustic feature sets or one type of entrainment.

Conclusions:
Our findings show that speech entrainment skills are largely developed during early adolescence with continued development possibly occurring across later adolescence. Additionally, results highlight the role of speech entrainment in successful conversation in this population, suggesting the import of continued exploration of this phenomenon in both neurotypical and neurodivergent adolescents. We also provide evidence of the value of using holistic measures that capture the multidimensionality of speech entrainment and provide a validated methodology for investigating entrainment across multiple acoustic features and entrainment types.
Attention Modulates the Role of Speakers' Voice Identity and Linguistic Information in Spoken Word Processing: Evidence From Event-Related Potentials
Authors: Ma Yunxiao , Yu Keke , Yin Shuqi , Li Li , Li Ping , Wang Ruiming 
Published: April 2023

Purpose:
The human voice usually contains two types of information: linguistic and identity information. However, whether and how linguistic information interacts with identity information remains controversial. This study aimed to explore the processing of identity and linguistic information during spoken word processing by considering the modulation of attention.

Method:
We conducted two event-related potentials (ERPs) experiments in the study. Different speakers (self, friend, and unfamiliar speakers) and emotional words (positive, negative, and neutral words) were used to manipulate the identity and linguistic information. With the manipulation, Experiment 1 explored the identity and linguistic information processing with a word decision task that requires participants' explicit attention to linguistic information. Experiment 2 further investigated the issue with a passive oddball paradigm that requires rare attention to either the identity or linguistic information.

Results:
Experiment 1 revealed an interaction among speaker, word type, and hemisphere in N400 amplitudes but not in N100 and P200, which suggests that identity information interacted with linguistic information at the later stage of spoken word processing. The mismatch negativity results of Experiment 2 showed no significant interaction between speaker and word pair, which indicates that identity and linguistic information were processed independently.

Conclusions:
The identity information would interact with linguistic information during spoken word processing. However, the interaction was modulated by the task demands on attention involvement. We propose an attention-modulated explanation to explain the mechanism underlying identity and linguistic information processing. Implications of our findings are discussed in light of the integration and independence theories.
Secure wireless communications for STAR‐RIS‐assisted millimetre‐wave NOMA uplink networks
Authors: Liu Ya , Huang Kaizhi , Sun Xiaoli , Yang Jie , Zhao Jianlei 
Published: April 2023

AbstractThis paper explores the potential application of simultaneously transmitting and reflecting reconfigurable intelligent surface (STAR‐RIS) in improving the physical layer security (PLS) of millimetre wave (mmWave) non‐orthogonal multiple access (NOMA) uplink communications. In particular, the legitimate users on both sides of STAR‐RIS send confidential information simultaneously to the base station (BS) while keeping it secret from the eavesdroppers near the BS by exploiting the STAR‐RIS to proactively regulate the electromagnetic propagation environment. By jointly designing the transmit power, the active beamforming at the BS, and the reflecting/transmitting coefficients at the STAR‐RIS, the authors' goal is to maximize the minimum secrecy capacity subject to the successive interference cancellation decoding order constraints. Due to the non‐convexity of the formulated problem, an efficient algorithm is proposed by capitalizing on alternating optimization, a penalty‐based approach, successive convex approximation, and semi‐definite relaxation. Firstly, a two‐layer iterative algorithm based on the penalty for the joint beamforming optimization sub‐problem is proposed. Then, the non‐convex problem is transformed into a convex positive semi‐definite programming problem for the transmit power sub‐problem. Numerical simulation results reveal that the STAR‐RIS‐aided system has more tremendous advantages and effectiveness in improving the PLS of mmWave NOMA uplink communication compared with the benchmark schemes.
Direct observation of solar wind proton heating from in situ plasma measurements
Authors: Mozer F. S. , Agapitov O. V. , Kasper J. C. , Livi R. , Romeo O. , Vasko I. Y. 
Published: April 2023

Aims. We determine the perpendicular and parallel proton heating rate in the solar wind, which is one of the primary goals of the Parker Solar Probe mission.
Methods. To estimate the perpendicular and parallel proton heating rates from direct particle measurements by the SPAN electrostatic analyzers, the strong correlation between the proton temperature and the solar wind speed must be removed. This speed dependence is removed by normalization factors that convert the instantaneous temperature to the value it would have if the solar wind speed were 400 km s−1. One-hour and five-hour averages of the normalized perpendicular and parallel temperatures, measured on orbits 6–9, between 20 and 160 solar radii, are compared to the radial dependence they would have if there were no heating.
Results. For the first time, perpendicular proton heating has been measured between 20 and 160 solar radii while there is neither heating nor cooling of the parallel protons below 70 solar radii. The extrapolated proton perpendicular temperature at one AU in a 400 km s−1 solar wind is 25 eV, which compares well with several earlier measurements. This result attests to the quality of the temperature measurements made by the particle detectors on the Parker Solar Probe. The heating rates, in ergs cm−3 s−1, that produced the observed perpendicular temperature are 6e−12 at 20 solar radii, 1e−13 at 50 solar radii, and 5e−14 at 160 solar radii.
Best Practice Guideline – Empfehlungen der DEGUM zur Durchführung und Beurteilung der Mammasonografie
Authors: Vogel-Minea Claudia Maria , Bader Werner , Blohmer Jens-Uwe , Duda Volker , Eichler Christian , Fallenberg Eva Maria , Farrokh André , Golatta Michael , Gruber Ines , Hackelöer Bernhard-Joachim , Heil Jörg , Madjar Helmut , Marzotko Ellen , Merz Eberhard , Müller-Schimpfle Markus , Mundinger Alexander , Ohlinger Ralf , Peisker Uwe , Schäfer Fritz KW , Schulz-Wendtland Ruediger , Solbach Christine , Warm Mathias , Watermann Dirk , Wojcinski Sebastian , Dudwiesus Heiko , Hahn Markus 
Published: April 2023

ZusammenfassungDie Mammasonografie hat sich seit vielen Jahren neben der Mammografie als wichtige Methode
zur Abklärung von Brustbefunden etabliert.Der Arbeitskreis Mammasonografie der DEGUM beabsichtigt mit der „Best Practice Guideline“
den senologisch tätigen Kolleginnen und Kollegen neben dem in Teil I publizierten aktuellen
Dignitätskriterien- und Befundungskatalog in dem vorliegenden Teil II die additiven und
fakultativen Anwendungsmodalitäten zur Abklärung von Brustbefunden zu beschreiben und dazu
DEGUM-Empfehlungen zu äußern, um die Differenzialdiagnose von unklaren Läsionen zu
erleichtern.Die vorliegende „Best Practice Guideline“ hat sich zum Ziel gesetzt, den Anforderungen zur
Qualitätssicherung und der Gewährleistung einer qualitätskontrollierten Durchführung der
Mammasonografie nachzukommen. Die wichtigsten Aspekte der Qualitätssicherung werden in diesem
Teil II der Best Practice Guideline erläutert.
Identification of High Platelet Reactivity Despite ADP P2Y12 Inhibitor Treatment: Two Populations in the Vasodilator-Stimulated Phosphoprotein Assay and Variable PFA-P2Y Shapes of Curve
Authors: Mariethoz Cyril , Scala Emmanuelle , Matthey-Guirao Elena , Rossel Jean-Benoît , Gomez Francisco Javier , Grandoni Francesco , Marcucci Carlo , Alberio Lorenzo 
Published: April 2023

Introduction Response to ADP P2Y12 receptor inhibition by clopidogrel can be evaluated by various techniques. Here, we compared a functional rapid point-of-care technique (PFA-P2Y) with the degree of biochemical inhibition assessed by the VASP/P2Y12 assay.
Methods Platelet response to clopidogrel was investigated in 173 patients undergoing elective intracerebral stenting (derivation cohort n = 117; validation cohort n = 56). High platelet reactivity (HPR) was defined as PFA-P2Y occlusion time <106 seconds or VASP/P2Y12 platelet reactivity index (PRI) >50%.
Results In the derivation cohort, receiver operator characteristics analysis for the ability of PFA-P2Y to detect biochemical HPR showed high specificity (98.4%) but poor sensitivity (20.0%) and a very low area under the curve (0.59). The VASP/P2Y12 assay revealed two coexisting platelet populations with different levels of vasodilator-stimulated phosphoprotein (VASP) phosphorylation: a fraction of highly phosphorylated, inhibited platelets and another of poorly phosphorylated, reactive platelets. Analysis of the PFA-P2Y curve shape revealed different types, categorized by time of occlusion (<106 seconds, 106 to 300 seconds, >300 seconds), and pattern (regular, irregular, and atypical). Noteworthy, curves with late occlusion and permeable curves with an irregular or atypical pattern correlated with VASP-PRI >50% and smaller sizes of the inhibited platelet subpopulation. Considering the PFA-P2Y shape of the curve for the detection of HPR improved sensitivity (72.7%) and preserved specificity (91.9%), with a rather high AUC (0.823). The validation cohort confirmed the VASP/P2Y12 assay data and the usefulness of considering the PFA-P2Y curve shape.
Conclusion In patients treated with acetylsalicylic acid and clopidogrel for 7-10 days, the VASP/P2Y12 assay reveals two coexisting subpopulations of differentially inhibited platelets, whose relative sizes predict global PRI and distinct PFA-P2Y curve patterns, indicating incomplete clopidogrel efficacy. The detailed analysis of both VASP/P2Y12 and PFA-P2Y is necessary for optimal detection of HPR.
Endoscopic Management of Benign Airway Stenosis in Coronavirus Disease 2019 Patients
Authors: Fiorelli Alfonso , Pecoraro Alfonso , Failla Giuseppe , Blasio Francesco De , Rendina Erino Angelo , Venuta Federico , Andreetti Claudio 
Published: April 2023

Background The aims of this study were to evaluate the results of endoscopic dilation for simple benign airway stenosis in coronavirus disease 2019 (COVID-19) patients and whether COVID-19 infection was associated with higher rate of recurrence compared with a control group.
Methods It was an observational multicenter study including consecutive patients with simple benign airway stenosis undergoing endoscopic dilatation with at least 6 months of follow-up. The outcome of patients with COVID-19 infection was compared with that of a control group in relation to patient and stenosis characteristics, and procedure type. Then, univariable and multivariable analyses identified the risk factors for recurrence.
Results Seventy-nine patients were included in the study; 56 (71%) of these developed airway stenosis after COVID-19 infection. COVID-19 patients presented a higher rate of stenosis due to prolonged intubation (82 vs. 43%; p = 0.0014); no other differences were found regarding demographic data, characteristics of stenosis, and procedure type. Twenty-four (30%) patients had recurrence after first dilatation (32% for No-COVID-19 vs. 26% for COVID-19 group; p = 0.70), and in 11 (35%) of these, the stenosis recurred after repeated endoscopic treatment (65% for No-COVID-19 vs. 45% for COVID-19 group; p = 0.40). Subglottic stenosis (p = 0.013) and the use of laser (p = 0.016) were significant predictive factors for stenosis recurrence.
Conclusion COVID-19 infection did not affect the outcome of endoscopic treatment of simple airway stenosis, and the treatment of these subsets of patients should not differ from that of general population.
Molecular Farming Strategy for the Rapid Production of Protein-Based Reagents for Use in Infectious Disease Diagnostics
Authors: Shanmugaraj Balamurugan , Jirarojwattana Perawat , Phoolcharoen Waranyoo 
Published: April 2023

AbstractRecombinant proteins are a major breakthrough in biomedical research with a wide range of applications from diagnostics to therapeutics. Strategic construct design, consistent expression
platforms, and suitable upstream and downstream techniques are key considerations to produce commercially viable recombinant proteins. The recombinant antigenic protein production for use
either as a diagnostic reagent or subunit vaccine formulation is usually carried out in prokaryotic or eukaryotic expression platforms. Microbial and mammalian systems dominate the
biopharmaceutical industry for such applications. However, there is no universal expression system that can meet all the requirements for different types of proteins. The adoptability of any
expression system is likely based on the quality and quantity of the proteins that can be produced from it. The huge demand of recombinant proteins for different applications requires an
inexpensive production platform for rapid development. The molecular farming scientific community has been promoting the plant system for nearly 3 decades as a cost-effective alternative to
produce high-quality proteins for research, diagnostic, and therapeutic applications. Here, we discuss how plant biotechnology could offer solutions for the rapid and scalable production of
protein antigens as low-cost diagnostic reagents for use in functional assays.
Management of Oral Parafunctional Habits: A Case Report
Authors: PS Murali , Achalli Sonika , Chandragiri Sandeep , Shetty Sameep 
Published: April 2023

AbstractOne of the most common problems seen in dental practice is oral parafunctional habits. Thumb sucking and tongue thrusting habits are by far the most common ones encountered. These have adverse effects on the dentition and the orofacial structure. Habit breaking appliances can be used to stop these habits and give best results if used at an early stage. Here we present two cases, one each of digit sucking and tongue thrusting treated effectively with habit breaking appliance.
Factors Associated with Recurrence in Chronic Subdural Hematoma following Surgery
Authors: Buakate Kritsada , Tunthanathip Thara 
Published: April 2023

Abstract
Background Recurrence is a frequent complication after surgery in a chronic subdural hematoma (CSDH). This study aimed to describe the recurrent rate of CSDH after surgery. In addition, a secondary objective aimed to explore factors associated with the recurrence of CSDH after surgery.
Methods A total of 141 surgical CSDH patients were analyzed in this retrospective study. The Cox regression method was used to conduct both univariate and multivariate analyses of variables associated with recurrence. As a result, the cumulative incidence of recurrence for each covariate survival curve was built after the final model.
Results Twenty-two percent of the patients showed evidence of recurrence. Initially, four variables (Glasgow coma scale score 3–8, clopidogrel, operative time, and amount of irrigated saline) had potential factors in univariate analysis but only clopidogrel and amount of saline irrigation were significantly associated with CSDH recurrence.
Conclusion Preoperative clopidogrel and the amount of saline irrigation were found to be associated with the recurrence rate. Factors associated with CSDH recurrence should be developed and validated as the clinical prediction tool for implication in general practice.
Benign Hepatic Neoplasms: An Imaging Review
Authors: Behera Rajendra Kumar , Chandola Stuti , Goyal Ankur , Sharma Raju 
Published: April 2023

AbstractBenign liver neoplasms are commonly encountered in clinical practice. Lesions like typical hemangioma may be confidently diagnosed on ultrasound, but for the majority of other liver lesions, multiphasic computed tomography (CT) and magnetic resonance imaging (MRI) are usually warranted. In lesions like adenomas, making the diagnosis alone is not sufficient; rather subcategorization is important to optimally manage these cases. Additionally, commonly observed variant lesions like the inflammatory subtype of hepatocellular adenoma and focal nodular hyperplasia mimic each other, which exacerbates the diagnostic dilemma. When observing cystic lesions, mucinous cystic neoplasm of the liver (MCN-L) needs to be differentiated from the more common non-neoplastic etiologies like hydatid cysts. Radiologists should also be acquainted with features of rare hepatic neoplasms like angiomyolipoma, paraganglioma, and inflammatory pseudotumor. In this review, we discuss the salient features and differentiating points to suggest the most likely diagnosis.
The Use of Ultrasound Contrast in Interventional Radiology
Authors: Tantrige Priyan , Ballal Khalid , Kelly Michael , Stefanidis Konstantinos , Huang Dean , Sidhu Paul S. , Yusuf Gibran Timothy 
Published: April 2023

AbstractUltrasound contrast agents have gained increasing popularity due to the high level of safety, real-time improved visualization, and ability to detect vascularity. As a result, contrast-enhanced ultrasound lends itself well to interventional radiology including in preprocedure assessment, intraprocedural guidance, and postprocedure evaluation. The authors aim to demonstrate the wide utility of contrast-enhanced ultrasound in both vascular and nonvascular intervention.