bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hubungan Pengetahuan Perawat dengan Penanganan Awal Pasien Cidera Kepala di IGD RSUD M.M Dunda Limboto
Authors: Yunus Pipin , Umar Arifin , Damansyah Haslinda , Tangahu Kristin 
Published: February 2025

ABSTRACT Head injury is a condition where there is an injury to the head which can cause damage to brain tissue due to trauma. Head injuries are the most common neurological disease among other neurological diseases which are usually caused by accidents. Handling head injuries requires good knowledge from nurses. Apart from that, age, gender, education and length of work are related to the initial treatment of head injuries. Objective: to determine the relationship between nurses' knowledge and initial treatment of head injury patients. Method: quantitative research design with analytical observational with a cross sectional approach, total population of 38 people with a total sample of 38 people or total sampling. Results: The results of the study showed that the highest knowledge of nurses was good knowledge at 34 people and the highest initial treatment for head injuries was good at 35 people with a value of pValue=0.000<0.05. Conclusion: there is a relationship between nurses' knowledge and the initial treatment of head injury patients, while there is no relationship between gender and length of work of nurses in the initial treatment of head injury patients. Suggestion: for nurses to increase their knowledge by attending several trainings in handling head injuries or exchanging information with fellow nurses to increase knowledge. Keywords: Head Injury, Knowledge, Initial Treatment ABSTRAK Cedera kepala merupakan suatu kondisi terjadinya cedera pada kepala yang dapat menyebabkan kerusakan jaringan otak akibat adanya trauma. Cedera kepala merupakan penyakit neurologis yang paling sering terjadi diantara penyakit neurologis lainnya yang biasa disebabkan oleh kecelakaan. Dalam penanganan cidera kepala membutuhkan pengetahuan yang baik dari perawat selain itu umur, jenis kelamin, pendidikan serta lama kerja berhubungan dengan penanganan awal cidera kepala. Tujuan penelitian ini untuk mengetahui hubungan pengetahuan perawat dengan penanganan awal pasien cidera kepala. Desain penelitian kuantitatif dengan observasional analitik dengan pendekatan cross sectional, jumlah populasi sebanyak 38 orang dengan jumlah sampel sebanyak 38 orang atau total sampling. Hasil: hasil penelitian menunjukan pengetahuan perawat tertinggi yaitu pengetahuan baik sebanyak 34 orang dan penanganan awal cidera kepala yang tertinggi yaitu baik sebanyak 35 orang dengan nilai pValue=0.000<0.05. Kesimpulan: terdapat hubungan pengetahuan perawat dengan penanganan awal pasien cidera kepala sedangkan tidak terdapat hubungan jenis kelamin dan lama kerja perawat dalam penanganan awal pasien cidera kepala. Saran: untuk perawat agar dapat meningkatkan pengetahuan dengan cara mengikuti beberapa pelatihan dalam penanganan cidera kepala atau saling bertukar informasi dengan sesama perawat dalam meningkatkan pengetahuan. Kata Kunci: Cidera Kepala, Pengetahuan, Penanganan Awal
Analisis Faktor yang Berhubungan dengan Janin Letak Sungsang
Authors: Yulianita Esti Dwi , Rosyidah Rafhani 
Published: February 2025

ABSTRACT Breech presentation is one of the leading causes of maternal mortality, although it occurs in only 2-3% of pregnancies, it carries significant risks of complications, including an increased risk of maternal death by 20-30%. The purpose of this study is to analyze the factors associated with breech presentation. This study uses an analytical design with a Cross-Sectional approach to analyze the relationship between several factors such as age, parity, polyhydramnios, maternal height, and placenta previa with the incidence of breech presentation. The study population consists of third-trimester pregnant women with a gestational age of 36-42 weeks who meet the inclusion criteria. The sample size of this study is 114 pregnant women in each group, calculated using the Lemeshow formula. Data was collected secondarily from medical records and analyzed using univariate analysis through frequency distribution tables, bivariate analysis using the chi-square test with a significance level of 0.05, and the prevalence of breech delivery was calculated using Prevalence Ratio (PR). Keywords: Breech Presentation, Pregnancy, Risk Factors. ABSTRAK Sungsang menjadi salah satu penyebab utama angka kematian ibu, yang walaupun hanya terjadi pada 2-3% kehamilan, tetapi memiliki risiko komplikasi yang signifikan, termasuk peningkatan risiko kematian ibu hingga 20-30%. Tujuan penelitian ini adalah menganalisis faktor yang berhubungan dengan janin letak sungsang. Penelitian ini menggunakan desain analitik dengan pendekatan Cross Sectional untuk menganalisis hubungan antara beberapa faktor seperti usia, paritas, hidramnion, tinggi badan ibu, dan placenta previa dengan kejadian letak sungsang. Populasi penelitian adalah ibu hamil trimester III dengan usia kehamilan 36-42 minggu yang memenuhi kriteria inklusi. Biesar sampiel pienielitian ini adalah 114 ibu hamil tiap kielompok yang di hitung mienggunakan rumus Liemieshow. Data dikumpulkan secara sekunder dari rekam medis dan dianalisis menggunakan analisis univariat dengan menggunakan tabel distribusi frekuensi, analisis bivariat dengan menggunakan uji chi – square dengan tingkat kemaknaan 0,05 serta besar prevalensi persalinan sungsang dihitung menggunakan RP (Rasio Prevalensi). Kata Kunci: Letak Sungsang, Kehamilan, Faktor Resiko.
Hubungan Antara Diabetes Melitus Tipe 2, Kadar High Density Lipoprotein dan Kadar Low Density Lipoprotein dengan Tipe Stroke di Rumah Sakit Umum Daerah Praya
Authors: Putri Baiq Shareny Aprina , Setiarini Rohmania , Azmi Fahriana , Tunjung I Wayan 
Published: February 2025

ABSTRACT Stroke is still one of the major health problems, not only in Indonesia but in the world. Stroke is the second leading cause of disability and death in the world. This study aims to analyze the relationship between type 2 diabetes mellitus (DM), high density lipoprotein (HDL) levels, and low density lipoprotein (LDL) levels with stroke type at Praya Regional General Hospital. This study used analytic observational method with cross-sectional design. The population was stroke patients who were hospitalized. The sampling technique was purposive sampling. The sample consisted of 91 respondents who met the inclusion and exclusion criteria. Data analysis was performed using the chi-square test. The results showed there was no significant relationship between type 2 diabetes mellitus and stroke type with a p-value of 0.684 (p-value ≥ 0.05). There is a significant relationship between HDL levels and stroke type with a p-value of 0.005 (p-value < 0.05). There is a significant relationship between LDL levels and non-hemorrhagic stroke type with a p-value of 0.031 (p-value < 0.05). In conclusion, there was no significant association between type 2 diabetes mellitus and stroke type, but there was a significant association between high density lipoprotein and low density lipoprotein levels with stroke type in Praya Regional General Hospital. Keywords: Stroke, Type 2 DM, HDL, LDL ABSTRAK Stroke masih menjadi salah satu masalah utama kesehatan, bukan hanya di Indonesia namun di dunia. Stroke menjadi penyebab utama kecacatan dan penyebab kematian nomor dua di dunia. Penelitian ini bertujuan untuk menganalisis hubungan antara diabtes melitus (DM) tipe 2, kadar high density lipoprotein (HDL), dan kadar low density lipoprotein (LDL) dengan tipa stroke di Rumah Sakit Umum Daerah Praya. Penelitian ini menggunakan metode observasional analitik dengan desain cross-sectional. Populasi adalah penderita penyakit stroke yang rawat inap. Teknik pengambilan sampel yaitu purposive sampling. Sampel terdiri dari 91 responden yang memenuhi kriteria inklusi dan eksklusi. Analisis data dilakukan menggunakan uji chi-square. Hasil penelitian menunjukkan tidak terdapat hubungan yang signifikan antara diabetes melitus tipe 2 dengan tipe stroke dengan p-value 0,684 (p-value ≥ 0,05). Terdapat hubungan yang signifikan antara kadar HDL dengan tipe stroke dengan p-value 0,005 (p-value < 0,05). Terdapat hubungan yang signifikan antara kadar LDL dengan tipe stroke non hemoragik dengan p-value 0,031 (p-value < 0,05). Kesimpulannya tidak ditemukan hubungan signifikan antara diabetes melitus tipe 2 dengan tipe stroke, tetapi terdapat hubungan signifikan antara kadar high density lipoprotein dan low density lipoprotein dengan dengan tipe stroke di Rumah Sakit Umum Daerah Praya. Kata Kunci: Stroke, DM Tipe 2, HDL, LDL
First Algerian artificial reef O.R.1 in Oran coastline: Construction, immersion and scientific monitoring
Authors: Hussein Kais Boumediene , Bensahla-Talet Lotfi , Chakouri Amine 
Published: February 2025

The first Algerian implantation of artificial reefs in Oran coastline was carried out on an experimental basis with the main objective to diversify and increase fishing potentialities along the Algerian coasts. University Oran1 Ahmed BENBELLA, the marine ecology association Barbarous, the Directorate of Fisheries and Fishery Resources of Oran (DPRH), and the Ministry of Fisheries and Fish Resources (MPRH) sought to direct fishing to a more sustainable fishing with more appropriate resource management. To this end, an artificial reef was implanted in order to increase biodiversity and fish biomass. O.R.1 (Oran Reef one) consisted of 68 modules, with two structures of 34 modules; each structure had a superposed form to create a chaotic structure (one to the East, and one to the West), with a total surface of 15 m2. Immersion was at 30m depth on a sandy substrate, with the immersion campaign lasting for 4 months, from April to July 2015. The scientific monitoring of the artificial reef allowed the authors to follow the evolution of structures (e.g., siltation) and biomass estimation of fauna and flora inhabiting the structure. After six months of immersion, monitoring in and around both structures reported the presence of more than 37 species, distributed among algae, mollusks gastropods, sponges and fish. Also, it was noticed that the number of species inventoried near the reef had been increasing since the beginning of monitoring, especially the biomass of fish such as red porgy, common two-banded seabream, black head seabream, amberjacks, scorpionfish, rainbow wrasse, and comber.
HighlightsThe study successfully located and marked the submerged reef by installing measuring devices to facilitate future management efforts. After six months of scientific monitoring, the findings revealed significant ecological and economic improvements. The overall richness of the reef increased by a factor of 9.25, indicating substantial ecological recovery. Additionally, the number of fish species observed on the reef has grown, accompanied by a notable recruitment of new individuals. Furthermore, the biomass of three economically valuable fish species increased by approximately 35 kilograms, yielding an economic benefit of 26,100 Algerian dinars per kilogram, equivalent to 144.73 euros per kilogram. These results underscore the reef's ecological recovery and its potential economic contribution to local fisheries.
Deciphering the anticancer potential of Lannea coromandelica targeting apoptosis signal-regulatory kinase 1 via advanced computational biology approaches
Authors: Ahmed Sheikh Sunzid , Rahman M Oliur 
Published: February 2025

Colorectal cancer (CRC) is one of the leading causes of cancer-related mortality globally. The rising expenses, significant side effects, and increasing resistance to traditional CRC treatments suggest the critical need for new and more effective therapeutic options. This study explored the anticancer potential of Lannea coromandelica (Houtt.) Merr. phytocompounds targeting the promising apoptosis signal-regulatory kinase 1 (ASK1) protein using computational biology approaches including molecular docking, ADMET analysis, molecular dynamics (MD) simulation, and MM/GBSA calculations. Virtual screening of the 17 phytoconstituents identified two lead compounds: ellagic acid and physcion, with binding affinities of -9.6 kcal/mol and -9.3 kcal/mol, respectively. ADMET analysis revealed favorable pharmacokinetic, pharmacodynamic, and toxicity profiles for the lead compounds. MD simulations supported the stability and compactness of the two leads in comparison to the control drug erbitux for 200 ns. The lead compounds displayed fewer rotatable bonds compared to Erbitux, resulting in lower torsional flexibility and greater stability during the simulations. PCA-based essential dynamics analysis demonstrated highly similar global motions in phase space for both lead compounds and erbitux, indicating comparable dynamic properties. Free binding energy calculations identified ellagic acid (-69.20 kcal/mol) as the superior lead compound over physcion (-65.68 kcal/mol). These results may open new avenues for the development of novel drug candidates targeting colorectal cancer.
Dhaka Univ. J. Biol. Sci. 34(1): 1-23, 2025 (January)
Psychological Impact and Anxiety in Pregnant Women During the COVID-19 Pandemic in the Southeastern Region of Bangladesh
Authors: Sattar Md Abdus , Rashid Fahmida , Akter Farhana , Das Rinku , Subrina Meher Subrina , Siddique Nargis , Sharmin Shahnaj , Begum Mosammat Rashida 
Published: February 2025

Introduction:The COVID-19 Pandemic has had a profound effect on the psychology of people around the world. It posed fear and anxiety to all, and pregnant women became more vulnerable. Various factors and the scarcity of treatment and hospital facilities during the lockdown worsened the mental state.
Aim:The study was performed to assess pregnant women's psychological impact and anxiety during the COVID-19 pandemic using a preset validated questionnaire.
Methodology:This cross-sectional study was conducted among 553 pregnant women, who visited for antenatal care in the outpatient department of Obstetrics and Gynecology, Chittagong Medical College Hospital, and private chambers of researchers from October to December 2020.
The psychological impact of the COVID-19 pandemic on pregnant women was assessed by the Italian version of the Impact of Event Scale (IES-R) questionnaire. A score of >24 was taken as significant. A six-item short-form of the Spielberger State-Trait Anxiety Inventory (STAI-6) scale was used to measure anxiety, and a score >36 was considered significant. Data were analyzed with SPSS-22 using the Chi-square test (for categorical data) and t-test (for numerical data) as appropriate. The NOVA test was done to calculate the significance between the groups. The P values <0.5 were taken as significant.
Results: Among the participants(N-553), more than half (54%) of the participants had different grades (mild-27%, moderate-09%, and severe-18%) of psychological impact during the COVID-19 pandemic. The Mean (±SD) total IES-R score was 25.65(± 12.334) (range: 0-68); the STAI-6 score was above the cut-off value (i.e., > 36) [40.50 (± 15.027)] (range: 5-77). Severe IES-R scores were observed in women who attended private chambers than in government hospitals (p<0.001), and also in women among urban patients (p=0.001), middle-income group (p=0.001), and women who did not contact a doctor (p=0.001).
Conclusion: The study revealed that more than half of the pregnant women experienced psychological impact during pregnancy. A subset of them might be vulnerable to PTSD. Almost all of the pregnant women in the study developed anxiety during COVID-19. Identifying protective factors targeted to eliminate the psychological impact and anxiety of pregnant women is warranted.
J MEDICINE 2025; 26: 5-12
Admission Blood Pressure as Predictors of Thirty Days Mortality in Community Acquired Pneumonia in a Tertiary Care Hospital of Bangladesh
Authors: Islam Md Khairul , Hossain Md Monoar , Khatun Sheikh Jamila , Hossain Fahima Sharmin , Zuhora Fatematuz , Rashid Md Mamunur , Zaman Mohammad Monir uz 
Published: February 2025

Background: Assessing admission blood pressure (BP) is crucial in predicting mortality community acquired pneumonia.
Methodology: This was a prospective longitudinal study at DMCH to explore hemodynamic predictors of the 30-day all-cause mortality, including deaths during hospital stay and after discharge in community-acquired pneumonia. Statistical analyses included the Z-proportion test, multivariate logistic regression, and ROC curve analysis. A p-value of less than 0.05 was considered statistically significant.
Results: The study's hospital mortality rate in community-acquired pneumonia was 14%. However, the all-cause mortality rate after 30 days of hospital admission increased to 22.6%. This was significantly associated with systolic blood pressure below 90 mmHg, diastolic pressure of 60 mm Hg or less, pulse of 40 mm Hg or less, and mean arterial pressure below 70 mm Hg (p<0.001). The multivariate logistic regression analysis indicated a significant association between blood pressure parameters and 30-day mortality in community-acquired pneumonia (CAP) patients. Systolic blood pressure (<90 mmHg) was found to be a significant predictor, with an Odds Ratio (OR) of 5.439 (95% CI: 1.565 to 18.895) and a p-value of 0.004. This suggests a significantly higher risk of mortality for subjects with systolic blood pressure below 90 mmHg compared to those with higher readings. However, diastolic blood pressure (<60 mmHg) did not show any significant association, as indicated by an OR of 0.871 (95% CI: 0.336 to 2.256) and a p-value of 0.775. Similarly, pulse pressure (<40 mmHg) did not exhibit any significant relationship with mortality, with an OR of 0.756 (95% CI: 0.090 to 6.377) and a p-value of 0.797. On the other hand, mean arterial pressure (<70 mmHg) emerged as another significant predictor, with an OR of 4.465 (95% CI: 1.280 to 15.579) and a p-value of 0.012. This suggests a significantly higher risk of mortality among subjects with mean arterial pressure below 70 mmHg compared to those with higher values.
Conclusion: Low systolic blood pressure (<90 mmHg) and mean arterial pressure (<70 mmHg) are associated with increased mortality risk in CAP patients.
J MEDICINE 2025; 26: 13-19
A Clinico-Epidemiological Study on Green Pit Viper Bite Attending Chittagong Medical College Hospital
Authors: Khurshid Tazrian , Alam Muhammed Syedul , Ely Naznin Fatema , Chowdhury Abul Faisal MD Nuruddin , Nahar Najmun , Nazir Nayana , Ghose Aniruddha 
Published: February 2025

Background: Snakebites are a neglected public health issue, particularly in rural tropical areas. In Bangladesh, Green Pit Viper bites are common, causing pain, swelling, and coagulopathy, leading to morbidity. Epidemiology of Green Pit Viper biting, frequency of coagulopathy and proper description of clinical features from Green Pit Viper bite is lacking. This study aims to describe clinical features, coagulopathy patterns, pre-hospital management, and outcomes of patients admitted with Green Pit Viper bite in Chittagong Medical College Hospital. Method: This study was cross-sectional and observational, analyzing medical records and data from the Snakebite Clinic at Chittagong Medical College Hospital (CMCH) in Bangladesh from 1st May 2017 to 30th April 2018. Informed written consent was obtained from patients, and their epidemiological data and clinical findings were recorded in a predefined case report form. The swelling extent was measured by comparing it to the non-bitten limb, and a 20-minute whole blood clotting test (WBCT) was performed in all patients to detect and monitor coagulopathy. Lab coagulation profiles were used to confirm coagulopathy and its reversal. Statistical analysis was conducted using SPSS-23. Results: The study included 112 patients with a median age of 32 years, predominantly adult males from rural areas. Bites commonly occur during outdoor activities. Pre-hospital management practices were widespread, with tourniquets and herbal remedies being common. Swelling was the primary local effect. Notably, 43% of patients developed coagulopathy, often with delayed onset. Most patients reached the hospital within 5 hours of the bite. Coagulopathy reversal was observed, and the majority of patients improved. Conclusions: This study sheds light on Green Pit Viper bites in Bangladesh, emphasizing coagulopathy's significance and the need for specific antivenom.
J MEDICINE 2025; 26: 28-35
Evaluation of Hematological Changes in Dengue Fever: experience of 2023 outbreak from Jashore, Bangladesh
Authors: Khan Tosdikur Rahman , Acherjya Goutam Kumar , Hossain Jahangir , Reza Selim , Nasrin Tahera 
Published: February 2025

Background: Dengue fever is a painful febrile illness caused by a mosquito-borne Arbovirus. Epidemic episodes often occur during the rainy season. Complete blood count (CBC) is essential in patients with dengue fever and serological tests are necessary to confirm it. This study aimed to evaluate the hematological changes in dengue fever patients in Jashore Medical College Hospital, Bangladesh. Methods: This prospective cross-sectional study was conducted in the Department of Medicine, Jashore Medical college Hospital, Bangladesh from July 2023 to Decembar 2023. The study involved 177 dengue fever patients identified through NS1 and/or IgM antibody tests. Purposive sampling was used for patient selection, and data analysis utilized SPSS version 23.0. Results: Analysis of hematological parameters on the 1st and 3rd days indicated significant shifts in platelet, leucocyte, neutrophil, and lymphocyte counts. Platelet count decreased from 99.67±96.17 x 109/L to 82.72±60.84 x 109/L (p=0.048). Leucocyte count rose from 6.43±3.01 x 109/L to 7.85±5.58 x 109/L (p=0.003), while neutrophil count decreased from 6.31±1.38 x 109/L to 5.44±1.36 x 109/L (p<0.001). Lymphocyte count also increased from 3.06±1.80 x 109/L to 3.78±1.19 x 109/L (p<0.001). No significant shifts were observed in hemoglobin (p=0.579) or hematocrit (p=0.639) levels. Conclusion: Among dengue fever patients, platelet and neutrophil counts decrease while leukocyte and lymphocyte counts increase significantly between the 1st and 3rd days. However, there are no significant shifts observed in hemoglobin or hematocrit levels in the same tenure.
J MEDICINE 2025; 26: 43-47
A 45 years old woman with biloptysis – A case report of broncho-billiary fistula
Authors: Dhar Uma , Islam Smaprity 
Published: February 2025

A bronchobiliary fistula or a biliobronchial fistula is a uncommon condition which occurs from an abnormal connection between the bronchial trees and biliary channel.It presents with pathognomonic bilious sputum or biloptysis with suspicious pneumonia.Broncho-biliary fistula is associated with Hydatid infection but recently found in patients with tumours.This case report presents a patient who had bronchobiliary fistula who had history of Adenocarcinoma of gall bladder with multiple space occupying lesions in liver and she underwent cholecystectomy.
J MEDICINE 2025; 26: 71-73