bluuebunny/crossref_metadata_2025_split huggingface dataset:
«14-ШІ БЕСЖЫЛДЫҚ» КЕЗІНДЕ ҚЫТАЙ – ЕУРОПА КОНТЕЙНЕРЛІК ПОЙЫЗДАРЫНА АРНАЛҒАН ҚХР-ДАҒЫ ИННОВАЦИЯЛЫҚ ӘЗІРЛЕМЕЛЕР МЕН БАЛАМАЛАРДЫ ЗЕРТТЕУ
Authors: ИЗТЕЛЕУОВА М.С. , СУЛЕЙМЕНОВА Д.Б. 
Published: February 2023

Контейнерные поезда Китай – Европа (далее – КП КНР – Европа) – это образцовый проект Китая по продвижению инициативы «Один пояс, один путь». В статье рассмотрена система управления государственными отраслями, механизмы распределения рыночных элементов, система услуг в рамках цепочки поставок в КНР, новые пути и возможности, открывшиеся в мировых переменах. Приведены вырезки из Плана «14-й пятилетки» коммунистической партии Китая, в котором пусть не указаны конкретные целевые показатели, но обозначены приоритетные направления развития, такие как улучшение управления и качества работы КП КНР – Европа, а также его продвижение, как на территории КНР, так и во всем мире, что поможет и железнодорожной отрасли, и экономике страны в целом.
Қытайдан Еуропаға контейнерлік пойыздарын (бұдан әрі – ҚХР – Еуропа КП) Қытайдың «Бір белдеу, бір жол» бастамасын ілгерілетуге арналған үлгілі жобасы. Мақалада мемлекеттік секторларды басқару жүйесі, нарықтық элементтерді бөлу механизмдері, ҚХР-да жабдықтау тізбегі шеңберіндегі қызметтер жүйесі, әлемдік өзгерістерде ашылған жаңа жолдар мен мүмкіндіктер қарастырылған. Қытай Коммунистік партиясының «14-ші бесжылдық» жоспарынан алынған кесінділер бар, онда нақты мақсаттар көрсетілмеген, бірақ дамудың басым бағыттары көрсетілген, мысалы, ҚХР – Еуропа КП менеджменті мен жұмысының сапасын жақсарту сияқты, сонымен қатар оны ҚХР аумағында және бүкіл әлемде жылжыту, бұл теміржол саласына да, жалпы ел экономикасына да көмектеседі.
Block trains from China to Europe (hereinafter – China – Europe BT) is an exemplary project of China to promote the "One Belt, One Road" initiative. The article examines the system of management of public sectors, mechanisms for the distribution of market elements, the system of services within the supply chain in China, new ways and opportunities that have opened up in world changes. There are clippings from the Chinese Communist Party's "14th Five-Year Plan", which does not indicate specific targets, but outlines priority areas of development, such as improving the management and quality of work of China – Europe BT, as well as its promotion, as in the territory of China and all over the world, which will help the railway industry and the country's economy.
МЕХАНИКАЛЫҚ ӘСЕРЛЕР-ЭЛЕКТР БЕРУ ЖЕЛІЛЕРІ МЕН ТЕМІР ЖОЛДАРДЫҢ БАЙЛАНЫС ЖЕЛІЛЕРІНІҢ ТІРЕКТЕРІНЕ ІЛІНГЕН ТАЛШЫҚТЫ-ОПТИКАЛЫҚ КАБЕЛЬДІҢ НЕГІЗГІ МӘСЕЛЕСІ
Authors: КЕМЕЛЬБЕКОВ Б.Ж. , БАТЫРБАЕВ Р. 
Published: February 2023

В статье представлен анализ технологии подвешивания оптоволоконного кабеля на опорах линий электропередачи или электрифицированных железнодорожных линиях, в очень агрессивной среде и сложных динамических неблагоприятных воздействиях внешней среды. Приведены сравнительные исследования технологии подвешивания оптоволоконного кабеля на линиях связи электрифицированных железных дорог. Результаты исследования и международный опыт в области построения и эксплуатации магистральных оптических сетей связи показывает, что наиболее эффективной в настоящее время является технология укладки волоконно-оптических линий связи в пластиковых коллекторах вдоль железных и автомобильных дорог.
Бұл мақалада электр берілісі желісінің тіректерінде немесе электрлендірілген теміржолдың байланыс желілерінде аспалы талшықты-оптикалық кабельдің технологиясы өте агрессивті ортада және сыртқы ортаның күрделі және динамикалық жағымсыз әсеріне ұшырау технологиясының талдауы келтірілген. электрлендірілген теміржолдың байланыс желілерінде аспалы талшықты-оптикалық кабельдің технологиясы жер астындагы талшықты-оптикалық байланыс желілерін құру технологиясы салыстырма зертеулері қарастырылган. Зертеу нәтижесінде магистральдық оптикалық-байланыс желілерін салу және пайдалану саласындағы зерттеулер мен халықаралық тәжірибелерден көрінеді: қазіргі кезде ең тиімдісі – бұл жол бойында пластикалық канализацияларда талшықты-оптикалық байланыс желілерін құру технологиясы. теміржол және автомобиль жолдарында тиімді.
This article presents an analysis of the technology of suspended fiber-optic cable in the poles of power transmission lines or electrified railway communication lines in a very aggressive environment and the complex and dynamic adverse effects of the external environment. Comparative studies of the technology of suspension fiber-optic cable in the communication lines of electrified railways, the technology of construction of underground fiber-optic communication lines are provided. The results of the study show that research and international experience in the field of construction and operation of backbone optical communication networks: the most effective at present is the technology of fiber-optic communication lines in plastic sewers along the road. effective on railways and highways.
ЖӨНДЕУАРАЛЫҚ АТҚАРЫМНЫҢ ЖҮК ВАГОНДАРЫНЫҢ ПАЙДАЛАНУ ҚАУІПСІЗДІГІНЕ ӘСЕРІ
Authors: ОМАРОВ А.Д. , ИСАЕНКО Э.П. , ОМАРОВА Г.А. , СУЛЕЕВА Н.З. 
Published: February 2023

В настоящее время задача научного обоснования указанных межремонтных нормативов обладает первостепенной значимостью. Под межремонтными нормативами понимаются календарный срок эксплуатации вагонов и пробег в межремонтном периоде, заявленные производителем в конструкторской документации на вагоны. В статье предложена методика определения показателей межремонтной наработки узлов и деталей вагонов, оказывающих влияние на безопасность грузовых вагонов в эксплуатационных условиях.
Қазіргі уақытта аталған жөндеу аралық нормативтерді ғылыми негіздеу міндеті бірінші дәрежелі мәнге ие. Жөндеу аралық нормативтер деп вагондарға арналған конструкторлық құжаттамада өндіруші мәлімдеген вагондарды пайдаланудың күнтізбелік мерзімі және жөндеу аралық кезеңдегі жүріс түсініледі. Мақалада пайдалану жағдайларында жүк вагондарының қауіпсіздігіне әсер ететін вагондардың тораптары мен бөлшектерінің жөндеуаралық жұмыс істеуінің көрсеткіштерін анықтау әдістемесі ұсынылған.
At present, the task of scientific substantiation of these inter-repair standards is of paramount importance. Inter-repair standards are understood as the calendar period of operation of cars and the mileage in the inter-repair period, declared by the manufacturer in the design documentation for cars. The article proposes a method for determining the indicators of inter-repair operation of components and parts of cars that affect the safety of freight cars in operational conditions.
AI-Powered Biomolecular-Specific and Label-Free Multispectral Imaging Rapidly Detects Malignant Neoplasm in Surgically Excised Breast Tissue Specimens
Authors: Pandey Rishikesh , Fournier David , Root Gary , Riccio Machele , Shirvalkar Aditya , Zamora Gianfranco , Daigneault Noel , Sapack Michael , Zhong Minghao , Harigopal Malini 
Published: February 2023

Context.—
Repeated surgery is necessary for 20% to 40% of breast conservation surgeries owing to the unavailability of any adjunctive, accurate, and objective tool in the surgeon’s hand for real-time margin assessment to achieve the desired balance of oncologic and cosmetic outcomes.

Objective.—
To assess the feasibility of using a multispectral autofluorescence imaging device for discriminating malignant neoplasm from normal breast tissue in pathology as a critical step in the development of a device for intraoperative use, and to demonstrate the device’s utility for use in processing and prioritizing specimens during frozen section and in the pathology grossing room.

Design.—
We performed a preliminary assessment of our device, called the TumorMAP system, on 172 fresh tissue blocks from 115 patients obtained from lumpectomy specimens at the time of initial gross examination and compared the device results with gold standard pathology evaluation.

Results.—
The preliminary results demonstrate the potential of our device in detecting breast cancer in fresh tissue samples with a sensitivity of 82%, a specificity of 91%, a positive predictive value of 84%, and a negative predictive value of 89%.

Conclusions.—
Our results suggest that the TumorMAP system is suitable for the detection of malignant neoplasm in freshly excised breast specimens and has the potential to evaluate resection margins in real time.
Reduction in Antibiotic Delivery Time Following Improving Pediatric Sepsis Outcomes Quality Improvement Initiative at a Major Children's Hospital
Authors: Gill Meghan , Raghu Vikram , Ferguson Elizabeth , Marcinick Adrienne , Rosen Johanna , Butler Gabriella , Horvat Christopher , Crowley Kelli 
Published: February 2023

OBJECTIVE
Sepsis causes morbidity and mortality in pediatric patients, but timely antibiotic administration can improve sepsis outcomes. The pharmacy department can affect the time from order to delivery of antibiotics. By evaluating the pharmacy process, this study aimed to decrease the time from antibiotic order to delivery to within 45 minutes.

METHODS
All antibiotic orders placed following a positive sepsis screen for acute care patients at a freestanding children's hospital from April 1, 2019, to December 31, 2019, were reviewed. Lean Six Sigma methodology including process mapping was used to identify and implement improvements, including educational interventions for providers. Outcome measures included time from antibiotic order placement to delivery and to administration. Additional assessment of process measures included evaluation of order priority, PowerPlan (an internally created order set) use, and delivery method.

RESULTS
Ninety-eight antibiotic orders for 85 patients were evaluated. In an individual chart of antibiotic delivery time, a trend towards faster delivery time was observed after interventions. Stat orders (40.5 minutes [IQR, 19.5–48]) were delivered more quickly than routine orders (51 minutes [IQR, 45–65]; p &lt; 0.001). Orders using the PowerPlan (20.5 minutes [IQR, 18.5–38]) were delivered more quickly than those that did not (47 minutes [IQR, 34–64]; p &lt; 0.01). Shorter time to administration was observed with pneumatic tube delivery (41 minutes [IQR, 20–50]) than with direct delivery to a health care provider (51 minutes [IQR, 31–83]; p &lt; 0.05) or to the automated dispensing cabinet's refrigerator (47 minutes [IQR, 41–62]; p &lt; 0.0001).

CONCLUSIONS
Multifactorial coordinated interventions within the pharmacy department improve medication delivery time for pediatric sepsis antibiotic orders.
Review of Tobramycin Dosing in Pediatric Patients With Cystic Fibrosis
Authors: Imburgia Taylor A. , Seagren Ryan M. , Christensen Hanna , Lasarev Michael R. , Bogenschutz Monica C. 
Published: February 2023

OBJECTIVEAn institution's tobramycin pharmacokinetics (PK) database was reviewed to evaluate the efficacy and safety of empiric tobramycin dosing and monitoring strategies used in pediatric patients with cystic fibrosis (CF). The relationship between patient age and tobramycin dosing needed to achieve the area under the curve (AUC) goal was investigated.METHODSRetrospective chart review was performed for patients who received tobramycin during a CF exacerbation from 2009 to 2019 who received PK monitoring by pediatric pharmacists. Tobramycin dosing needed to achieve an AUC of 100 mg·hr/L was calculated for each patient. Serum creatinine and concomitant nephrotoxin use were collected as surrogate nephrotoxicity endpoints to evaluate safety.RESULTSGoal AUC (100 ± 15 mg·hr/L) was achieved based on initial or repeat PK calculations in 43.5% (95% CI, 37.7–49.3) of 85 unique patients across 326 encounters. Patients with calculated recommended doses of 9.5 to 11.9 mg/kg every 24 hours empirically achieved goal AUC in 77% (78/101) of encounters. The odds of achieving goal AUC were 56% higher for children aged 10 vs 5 years (OR = 1.56; 95% CI, 1.04–2.34; p = 0.033) and 32% higher for children aged 15 vs 10 years (OR = 1.32; 95% CI, 1.07–1.61; p = 0.008). Overall rates of acute kidney injury and concomitant nephrotoxin use were 10.8% (95% CI, 6.2–15.5) and 80.7% (95% CI, 74.3–87.1), respectively.CONCLUSIONSDesired AUC was achieved by 43.5% of pediatric patients with CF using tobramycin 10 mg/kg every 24 hours. Older patient age was associated with higher initial AUC attainment and fewer dose modifications. Younger children may require higher weight-based dosing to meet AUC goals.
Development of Basic Physics Experimental Props 1 on Fluid Viscosity Material
Authors: Rahmani Yunita 
Published: February 2023

This research objectives were to Describe students' perception of the readability test of arduino-based basic physics experiment props on fluid viscosity material. The method used in this research is the Research and Development (R&D) method with ADDIE development model. Products are made using Arduino Uno and Arduino IDE software with C++ programming language. The data samples used in this study were 42 students of JPMIPA FKIP Unib (Physics Education, Chemical Education, Biology Education and Science Education). The instruments used in this student perception questionnaires. The student perception was interpreted by Likert Scale. Student perception was reviewed from 7 aspects, namely the efficiency aspects of the tool, the association with the lecture material, containing the value of education, tool durability, aesthetics, technical components and tool safety. The results obtained from this study showed that the props developed fall into the category of is the best with an average score of 87%
A prática de análise linguística na alfabetização por meio do projeto Ananse durante a pandemia da Covid 19
Authors: Giovani Fabiana , Machado Ana Lúcia 
Published: February 2023

Ao considerar a narrativa como um caminho de pesquisa e de se fazer ciência, bem como delegar a ela um fundamental papel na formação humana, objetivamos, neste texto, refletir como um projeto de leitura denominado Ananse contribuiu para a prática de análise linguística e como foi o processo de domínio e manuseio da linguagem escrita por uma criança de uma turma de 2° ano, de uma escola pública federal, a qual denominaremos L. A reflexão ganha destaque, uma vez que a experiência vivida ocorreu nas aulas remotas, num período singular que foi a pandemia da Covid-19. Desse modo, a partir do saber de experiência, narramos como uma criança em fase de alfabetização está dialogando com a literatura e com os conhecimentos que vem construindo com/sobre os textos escritos por meio da prática de análise linguística. Fundamentamos a nossa reflexão teórico-metodológica em autores como Bakhtin (1992), Geraldi (2004) e Larrosa (2002). A reflexão narrada explicita, através da experiência de L, como a prática de análise linguística advinda do Ananse possibilita a construção de um caminho possível e viável para contribuir com a alfabetização através da interação com textos e com a vida, sendo esta mediada pela linguagem.
First Report of the Crapemyrtle Aphid Tinocallis kahawaluokalani (Hemiptera : Aphididae) and its Relate Natural Enemies in Gabon
Authors: René Noel Poligui , Emelie Arlette Apinda Legnouo , Henri Nzandi 
Published: February 2023

A study was carried out among some green spaces in Gabon, mainly in Libreville, Lambarene, Mouila, Franceville and Mitzic, from August 2019 to October 2021. The aim was to assess the presence and impact of the japanese aphid Tinocallis kahawaluokalani Kirkaldy (Hemiptera : Aphididae), and its relate natural enemies, using one time visual observations on Crapemyrtle shrubs. This ornamental plant pest was recorded, occurring on leaves of Lagerstroemia indica (L.) Pers. (Lythraceae). Seven local beneficial insect species were observed predating on this aphid, mainly three hoverflies Ischiodon aegyptius Wiedemann, Paragus borbonicus Macquart, Asarkina sp. (Diptera : Syrphidae), three ladybird species Platynaspis capicola Crotch, Scymnus interruptus Goeze and Chilocorus nigritus Fabricus (Coleoptera : Coccinellidae), and the brown lacewing Micromus sp. (Neuroptera : Hemerobiidae), as natural enemies of T. kahawaluokalani, hilighting a local promizing way for biocontrol of this pest. These findings are a new record for this insect pest from the Gabon and Africa.
The Use of Dimethyl Biguanide as a Potential Treatment for Alzheimer's Disease in Rats
Authors: A. Abosharaf Hamed , Elsonbaty Yasmin , Tousson Ehab , M. Mohamed Tarek 
Published: February 2023

Amis: Alzheimer’s disease (AD) is one of the most rapidly growing diseases in recent times. Despite extensive research to find an appropriate medicine, there has been no effective drug until now.
Study Design: The present study was designated to investigate the therapeutic impact of antihyperglycemic dimethyl biguanide on Alzheimer’s disease symptoms.
Methodology: Alzheimer’s disease was induced in male rats by AlCl3 and D-galactose at doses of 50 and 120 mg/kg daily for one month. Then, for the next four weeks, rats were given oral dimethyl biguanide (200 mg/kg daily).
Results: The obtained data indicated an increase in the arrival time of the AD rat group (G2) compared to the control group (G1). In addition, the AD rat group showed an elevation in glucose level, oxidative stress, liver, and kidney function. Importantly, dimethyl biguanide was able to ameliorate these unpleasant outcomes in G3. Interestingly, dimethyl biguanide was able to reduce GFAB immunoreactivity in the dimethyl biguanide -treated group (G3) compared to the AD group (G2).
Conclusion: In fact, dimethyl biguanide can delay the symptomatology of AD.
Evaluation of Subsoil Competence for Foundation Design in Rumuokwuta, Port Harcourt, Eastern Niger Delta
Authors: Morrison Tammy , Ekine Esonanjor Erefama 
Published: February 2023

Aim: A subsurface geotechnical investigation was carried out for the purpose of establishing the depth of competent soil for foundation design and construction of a one-storey building.
Study Design: The study was aimed at assessing the subsoil competence for a foundation design in the Eastern Niger Delta using engineering geology and geotechnics.
Place and Duration of Study: The research was conducted in three locations along the Rumuokwuta axis of Port Harcourt (the eastern Niger Delta) between April and September 2019.
Method: The study involved both field sampling and laboratory analysis. This involved soil boring for the retrieval of disturbed and relatively undisturbed samples for analysis, which involves grain size analysis, the Atterberg limits, moisture content, and unit weights. Also, Oedometer consolidation Oedometer and undrained, unconsolidated triaxial tests were carried out.
Results: The study revealed two main stratigraphic layers that are mostly fine within the shallow foundation level (0.0–3.0m). From the results, the soil exhibited the following geotechnical properties: liquid limit (41-46%), plastic limit (21-23%), plasticity index (18-24%), and moisture content range (20.6-24.7%). The undrained cohesion value is 55 kPa, and the average frictional angle is 5o. The coefficients of compression (Mv) and consolidation (Cv) were 0.20 m2 /MN and 40.7 m2/yr, respectively.
Conclusion: With the moderate bearing and settlement values within the shallow foundation level, the feasibility of adopting a shallow foundation for the purposed structure is tolerable. A shallow foundation (1.4m minimum) with an allowable bearing pressure of 100 kPa is therefore recommended.
Ocular Surface Alterations Related to Cataract Surgery
Authors: Mohamed Alyaa Ismail , Nassar El-Sayed Abbas , Elsoht Rabab Mohamed , Shaheen Mohamed Abdlfattah 
Published: February 2023

Background: Dry eye syndrome is a multifactorial disease of pre-corneal tear film that results in ocular discomfort, visual disturbance and tear film instability, with potential damage to the ocular surface. The aim of the work was to evaluate the ocular surface alterations related to cataract surgery either phacoemulsification or extracapsular cataract extraction surgeries.
Methods: This prospective observational study included 60 patients with cataract. Patients were divided into 2 equal groups: Group1 included patients who had scheduled for phacoemulsification. Group 2 included patients who had scheduled for extracapsular cataract extraction surgery. All patients were subjected to full history taking, complete ophthalmic evaluation, OSDI score test, Schirmer tests, invasive break up time tests (IBUT), and non- invasive break up time tests (NIBUT).
Results: Postoperative BCVA test in both groups was significantly better compared to preoperative tests after 1 week, 1 month, and 3 months while postoperative Schirmer test, IBUTT test, non IBUTT test, and OSDI test were significantly worse compared to preoperative in both groups after 1 week, 1month and 3 months (P value = 0.05).
Conclusions: Patients who had scheduled for phacoemulsification showed a significantly better BCVA test, OSDI test, Schirmer test, IBUTT test, and non IBUTT test after 1 week,
1month and 3 months compared to extracapsular cataract extraction group.
Seropositivity for Viral Infectious Diseases in Leukemia Patients and Its Relationship with Cytogenetic Changes
Authors: Eslami Mohammad , Falahati Vahid , Siroosbakht Soheila , Nikoohemmat Mahdi , Kianifar Farzaneh , Arabi Nahid 
Published: February 2023

Introduction: Leukemias are involving the bone marrow and the soft tissues in the inner parts of the bones. This malignancy is the most common pediatric cancer, and its etiologic causes are not well understood. This multifactorial disease is believed to be linked to genetic and non-hereditary environmental factors. Cytogenic analyses of chromosomal abnormalities provide diagnostic and prognostic values in leukemia patients. Given the high prevalence of viral diseases and clinical suspicions of the relationship between certain viral infections and leukemia, it is necessary to investigate this possible relationship, especially in third-world countries. The present study recruited 65 children with leukemia (AML, CML, or ALL) who were presented to two tertiary hospitals. At first, all the patients underwent testing for HBV, HCV, CMV, EBV, and HIV. Bone marrow specimens were studied for identifying possible chromosomal abnormalities in cytogenic investigations. According to our findings, there was a relationship between the incidence of leukemia, the 12:21 chromosomal translocation, and CMV infection. Therefore, preventing CMV infection can lead to a reduced incidence of leukemia. It is expected that the findings of this study enlighten scientists to conduct more extensive research on the relationship between viral diseases and leukemia in third-world countries.
Materials and Methods: The present study recruited 65 children with leukemia (AML, CML, or ALL) who were presented to two tertiary hospitals. At first, all the patients underwent testing for HBV, HCV, CMV, EBV, and HIV. Bone marrow specimens were studied for identifying possible chromosomal abnormalities in cytogenic investigations.
Results: According to our findings, there was a relationship between the incidence of leukemia, the 12:21 chromosomal translocation, and CMV infection. Thus, CMV infection is highly suspected to cause a chromosomal abnormality and predispose children to leukemia . Therefore, preventing CMV infection can lead to a reduced incidence of leukemia.
Conclusion: In this study, we demonstrated that acute Lymphoblastic Leukemia is relevant to the 12:21 chromosomal translocation and CMV virus infections, So the reduction in leukemia prevalence is dependent on the prevention of CMV disease. It is expected that the findings of this study enlighten scientists to conduct more extensive research on the relationship between viral diseases and leukemia in third-world countries.