bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thermal and Dielectric Behaviour of Polymer-Based Nanocomposites Flexible Sheets as Highly Stable Dielectric Materials
Authors: Pervaiz S. , Kanwal N. , Shahzad A. , Saleem M. , Khan I. A. 
Published: January 2023

The silica zinc oxide nanoparticles filled poly-vinylidene-fluoride (PVDF)-based nanocomposite flexible sheets (NC FSs) are synthesized by co-precipitation method. The X-ray diffraction patterns reveal the development of various diffraction planes related to zinc oxide (ZnO) and SiO2 phases. The crystallinity of ZnO phase is decreased with increasing weight percent (wt.%) of silica nanofillers (NFs). The scanning electron microscope microstructure of synthesized PVDF-based NCs FSs is changed with increasing wt.% of silica NFs. The energy-dispersive X-ray spectroscopy and Fourier-transform infrared spectroscopy analyses confirm the presence of different elements and the formation of chemical bonding between them. In high temperature region, the weight-loss of synthesized PVDF-based NCs FSs is decreased from 89.90% to 49.26% with increasing wt.% of silica NFs. The values of dielectric permittivity, loss-factor, impedance, and AC-conductivity of PVDF-based NC FSs synthesized for maximum amount of silica NFs are found to be 13.7, 0.03, 0.16 MΩ, and

19.9
×

10

−
6

S/m, respectively. Results show that the synthesized PVDF-based NC FSs are the potential candidates of light emitting diodes and energy storage devices.
PHD2 Constrains Antitumor CD8+ T-cell Activity
Authors: Bisilliat Donnet Charlotte , Acolty Valérie , Azouz Abdulkader , Taquin Anaëlle , Henin Coralie , Trusso Cafarello Sarah , Denanglaire Sébastien , Mazzone Massimiliano , Oldenhove Guillaume , Leo Oberdan , Goriely Stanislas , Moser Muriel 
Published: January 2023

AbstractThe prolyl hydroxylase domain/hypoxia-inducible factor (PHD/HIF) pathway has been implicated in a wide range of immune and inflammatory processes, including in the oxygen-deprived tumor microenvironment. To examine the effect of HIF stabilization in antitumor immunity, we deleted Phd2 selectively in T lymphocytes using the cre/lox system. We show that the deletion of PHD2 in lymphocytes resulted in enhanced regression of EG7-OVA tumors, in a HIF-1α–dependent manner. The enhanced control of neoplastic growth correlated with increased polyfunctionality of CD8+ tumor-infiltrating lymphocytes, as indicated by enhanced expression of IFNγ, TNFα, and granzyme B. Phenotypic and transcriptomic analyses pointed to a key role of glycolysis in sustaining CTL activity in the tumor bed and identified the PHD2/HIF-1 pathway as a potential target for cancer immunotherapy.
Inhibiting IGF1R-mediated Survival Signaling in Head and Neck Cancer with the Peptidomimetic SSTNIGF1R
Authors: Stueven Noah A. , Beauvais DeannaLee M. , Hu Rong , Kimple Randall J. , Rapraeger Alan C. 
Published: January 2023

Previous studies have shown that the type I IGFR (IGF1R) suppresses apoptosis when it is autoactivated by coupling its extracellular domain to a matrix adhesion receptor complex consisting of syndecan-1 (Sdc1) and αvβ3 or αvβ5 integrin. We now report that head and neck squamous cell carcinoma (HNSCC) relies on this receptor complex. Disruption of the complex in HNSCC cells in vitro with a peptide mimetic of the organizer site in Sdc1 (called SSTNIGF1R) inactivates IGF1R, even in the presence of IGF1, and relieves the suppression of apoptosis signal-regulating kinase-1 (ASK1), dramatically reducing tumor cell survival. Normal epithelial cells do not assemble this receptor complex, require IGF1 to activate the IGF1R, and are refractory to SSTNIGF1R. In vivo, SSTNIGF1R reduced the growth of patient-derived HNSCC tumors in immunodeficient mice by 85%–95%. IGF1R's assimilation into the matrix receptor complex, which is detected in these tumors using the proximity ligation assay (PLA), is quantitatively disrupted by SSTNIGF1R, coinciding with ASK1 activation. PLA also detects the IGF1R-containing receptor complex in the archival sections of tonsil carcinomas, whereas the adjacent benign epithelium is negative. Likewise, PLA screening of oropharyngeal and adenoid cystic tumor microarrays demonstrated that over 95% of the tumors contained this unique receptor complex with no detectable expression in benign tissue. These findings suggest that HNSCC upregulates and is highly dependent on IGF1R signaling via this adhesion receptor complex. Targeting this mechanism with novel therapeutics, including highly specific SSTNIGF1R, is likely to offer promising outcomes for patients with carcinoma.Significance:A newly developed biomarker reveals upregulation of an antiapoptotic IGF1R-integrin-syndecan receptor complex in head and neck cancer and documents disruption of the complex in patient-derived tumor xenografts (PDX) treated with the inhibitor SSTNIGF1R. A corresponding blockade in PDX growth in the presence of this inhibitor demonstrates that therapies designed to target this mechanism will likely offer promising outcomes for patients with head and neck cancer.
Effects of Blood Pressure and Arterial Stiffness on Retinal Neurodegeneration: Cross-Sectional and Longitudinal Evidence From UK Biobank and Chinese Cohorts
Authors: Huang Yining , Yuan Yixiong , Wang Yujie , Hui Ziwen , Shang Xianwen , Chen Yanping , Zhang Shiran , Liao Huan , Chen Yifan , He Mingguang , Zhu Zhuoting , Wang Wei 
Published: January 2023

Background:
Hypertension might be a modifiable risk factor for neurodegeneration diseases. However, the associations between blood pressure (BP), arterial stiffness index and retinal neurodegeneration remain unclear.

Methods:
This study used cross-sectional data from the United Kingdom BioBank (UKB) and longitudinal data from the Chinese Ocular Imaging Project (COIP). The macular ganglion cell-inner plexiform layer thickness (mGCIPLT) and macular retinal nerve fiber layer thickness were measured using spectral domain optical coherence tomography imaging. Swept-source optical coherence tomography was performed to obtain the longitudinal trajectory of the mGCIPLT and peripapillary retinal nerve fiber layer thickness in the COIP cohort. Multivariable linear models were used to analyze the associations between BP and retinal measurements.

Results:

In a cross-sectional analysis of 22 801 participants from UKB, thinner mGCIPLT was related to higher systolic BP (β: −0.103 [−0.146 to −0.061];
P
<0.001), and higher diastolic BP (β: −0.191 [−0.265 to −0.117];
P
<0.001), and was significantly associated with higher mean arterial pressure (β: −0.174 [−0.238 to −0.109];
P
<0.001) and higher mean pulse pressure (β: −0.080 [−0.139 to −0.020];
P
=009). In a longitudinal analysis of 2012 eligible COIP participants, higher levels of baseline systolic BP, diastolic BP, mean arterial pressure, and mean pulse pressure were associated with faster thinning in mGCIPLT and peripapillary retinal nerve fiber layer thickness (all
P
<0.001). The strongest association was the effect of mean arterial pressure on mGCIPLT (β: −0.118 [−0.175 to −0.061];
P
<0.001). The results of the analysis of macular retinal nerve fiber layer thickness and peripapillary retinal nerve fiber layer thickness were consistent with those of mGCIPLT.

Conclusions:
BP levels were independently and consistently associated with various retinal neurodegenerative exacerbations.
Adult Age Differences in the Temporal Dynamics of Motivated Attention
Authors: Sullivan Margot D. , Kudus Farrah , Dyson Benjamin J. , Spaniol Julia 
Published: January 2023

Abstract
Reward-based motivation modulates attention and cognitive control across the life span, but little is known about age differences in the temporal dynamics of motivated attention. The current study examined the effects of financial incentives on visual attention using ERPs. Participants (26 younger, aged 18–33 years; 24 older, aged 65–95 years) completed an incentivized flanker task in which trial-level incentive cues signaled the availability of performance-contingent reward, and subsequent alerting cues signaled the onset of the flanker target. ERP components of interest included cue-related components (incentive-cue P2 and contingent negative variation, and alerting-cue N1) as well as target-related components (target N1 and P3). Transient effects of incentives were assessed by comparing ERP amplitudes across incentive and non-incentive trials from mixed-incentive blocks. Sustained effects of incentives were assessed by comparing ERP amplitudes across non-incentive trials from mixed-incentive blocks and non-incentive trials from pure non-incentive blocks. Younger adults showed transient effects of incentives on all components, whereas older adults showed these effects for incentive-cue P2 and alerting-cue N1 only. Both age groups showed sustained effects of incentives on cue-locked ERPs, but only younger adults showed sustained effects on target-locked ERPs. RT patterns mirrored the ERP findings, in that younger adults showed greater incentive-based modulation than older adults, but at a greater cost to accuracy. Overall, these findings reveal widespread age differences in the dynamics of incentive-motivated attention and cognitive control, particularly at longer timescales.
Transcranial Direct Current Stimulation Modulates Working Memory Maintenance Processes in Healthy Individuals
Authors: Nikolin Stevan , Martin Donel , Loo Colleen K. , Boonstra Tjeerd W. 
Published: January 2023

AbstractThe effects of transcranial direct current stimulation (tDCS) at the pFC are often investigated using cognitive paradigms, particularly working memory tasks. However, the neural basis for the neuromodulatory cognitive effects of tDCS, including which subprocesses are affected by stimulation, is not completely understood. We investigated the effects of tDCS on working memory task-related spectral activity during and after tDCS to gain better insights into the neurophysiological changes associated with stimulation. We reanalyzed data from 100 healthy participants grouped by allocation to receive either sham (0 mA, 0.016 mA, and 0.034 mA) or active (1 mA or 2 mA) stimulation during a 3-back task. EEG data were used to analyze event-related spectral power in frequency bands associated with working memory performance. Frontal theta event-related synchronization (ERS) was significantly reduced post-tDCS in the active group. Participants receiving active tDCS had slower RTs following tDCS compared with sham, suggesting interference with practice effects associated with task repetition. Theta ERS was not significantly correlated with RTs or accuracy. tDCS reduced frontal theta ERS poststimulation, suggesting a selective disruption to working memory cognitive control and maintenance processes. These findings suggest that tDCS selectively affects specific subprocesses during working memory, which may explain heterogenous behavioral effects.
The management of scientific and technological infrastructures: The case of the Mexican National Laboratories
Authors: Munguía Leonardo , Robles-Belmont Eduardo , Escalante Juan Carlos 
Published: January 2023

Abstract
The effectiveness of research units is assessed on the basis of their performance in relation to scientific, technological, and innovation production, the quality of their results, and their contribution to the solution of scientific and social problems. We examine the management practices employed in some Mexican National Laboratories to identify those practices that could explain their effectiveness in meeting their objectives. The results of other research that propose common elements among laboratories with outstanding performance are used and verified directly in the field. Considering the inherent complexity of each field of knowledge and the sociospatial characteristics in which the laboratories operate, we report which management practices are relevant for their effectiveness, how they contribute to their consolidation as fundamental scientific and technological infrastructures, and how these can be translated into indicators that support the evaluation of their performance.
Field, capital, and habitus: The impact of Pierre Bourdieu on bibliometrics
Authors: Schirone Marco 
Published: January 2023

AbstractThis study is a critical review aimed at assessing the reception received in bibliometric research by the theories and concepts developed by the sociologist Pierre Bourdieu. The data set consists of 182 documents, including original articles, editorial material, review articles, conference papers, monographs, and doctoral dissertations. A quantitative analysis was used to establish the authors and countries that most frequently make use of Bourdieu’s theories, as well as the most popular concepts, which were identified as “field,” followed by “symbolic capital” and “social capital.” Then, the article discusses the impact of Bourdieusian key concepts such as “field.” Among the findings, the following are noteworthy: the integration of his field theory into pre-existing bibliometric conceptualizations of research fields, especially when power relations are problematized; the use of “symbolic capital” in connection with citation analysis and altmetrics; and greater interest in Bourdieu’s theories compared to his methods, although some sources have used Bourdieu’s preferred statistical method, correspondence analysis. Moreover, Bourdieu’s theoretical impact is noticeable in research on journals, university rankings, early career researchers, and gender. The paper’s conclusions point to future research paths based on concepts less used in the bibliometric literature, such as “delegation.”
Impact of the 2022 OSTP memo: A bibliometric analysis of US federally funded publications, 2017–2021
Authors: Schares Eric 
Published: January 2023

AbstractOn August 25, 2022, the White House Office of Science and Technology Policy (OSTP) released a memo regarding public access to scientific research. Signed by Director Alondra Nelson, this updated guidance eliminated the 12-month embargo period on publications arising from U.S. federal funding that had been allowed from a previous 2013 OSTP memo. Although reactions to this updated federal guidance have been plentiful, to date there has not been a detailed analysis of the publications that would fall under this new framework. The OSTP released a companion report along with the memo, but it only provided a broad estimate of total numbers affected per year. Therefore, this study seeks to more deeply investigate the characteristics of U.S. federally funded research over a 5-year period from 2017–2021 to better understand the updated guidance’s impact. It uses a manually created custom filter in the Dimensions database to return only publications that arise from U.S. federal funding. Results show that an average of 265,000 articles were published each year that acknowledge US federal funding agencies, and these research outputs are further examined by publisher, journal title, institutions, and Open Access status. Interactive versions of the graphs are available at https://ostp.lib.iastate.edu/.
Dating Medieval Ghent (Belgium): Dendrochronological and Typological Survey of the Roofs of Saint Nicholas’ Church
Authors: Debonne Vincent , Haneca Kristof 
Published: January 2023

Abstract
Roof construction is a key element while documenting and studying building traditions in historical towns. In the city centre of Ghent (Belgium), numerous roofs of large monuments (churches, merchants’ halls, town halls) as well as historical houses from the pre-industrial era are still in place. Tree-ring research has been carried out on several intact roof constructions since the 1990s. The dated roofs range from the mid-13th to the 17th century. Recent research has revealed the presence of historical roofs in the church of St. Nicholas, an iconic building in the city’s historical centre. Tree-ring research has dated the roof constructions of the nave and the choir to the first and second quarters of the 13th century, which makes them the oldest preserved examples of carpentry in Ghent and among the oldest in Flanders (northern Belgium). These and other such dating results for the Ghent region allow for the development of a typology for (late) medieval and early modern roof constructions and provide context for a better understanding of the procurement, trade, and transport of building timber from the early 13th century to the early modern era.
Mummy Labels: A Witness to the Use and Processing of Wood in Roman Egypt
Authors: Blondel François , Huebner Sabine R. , Pearson Charlotte , Stoffel Markus 
Published: January 2023

Abstract
Mummy labels are relics found in large quantities in Egypt, often in an excellent state of preservation (like most woods preserved in arid environments). As a result, they are widespread in Roman Egyptian collections of many museums. These labels reflect funerary practices that possess Egyptian and Roman influences and are an important source of historical and archaeological information. These corpora of mummy labels offer several possibilities for investigation. The inscriptions on these labels have been the subject of an international project (Death on the Nile) in which all accessible objects were recorded in a database. However, the potential of these funerary objects extend beyond the inscriptions to the methods of manufacturing and cutting, the choice of species used, and their dendrochronological potential to better define their chronology and possibly their provenance. The study of mummy labels allows us to propose a new typology, some forms of which seem to be limited to certain necropolises. Mummy labels, whether made by the family of the deceased or by specific workshops, show that their realizations vary greatly, ranging from coarse specimens to others with beautiful detailing. They are made from endemic as well as imported species, which are symbolic of long-distance trade, especially for conifer trees, which are well represented. Their dendrochronological potential has also been demonstrated in numerous studies, some of which have allowed the identification of labels from the same tree, supported by inscriptions attesting to the same family relationship.
Enhanced Impact of Autumn North Tropical Atlantic Sea Surface Temperature Anomalies on Subsequent Winter Snowfall in Northeast China after 2001
Authors: Xu Shiqi , Fang Yihe , Lin Yitong , Sun Xuguang , Yang Xueyan , Gong Zhiqiang 
Published: January 2023

Abstract
This study reveals that the relationship between autumn north tropical Atlantic (NTA) sea surface temperature (SST) anomalies and Northeast China’s winter snowfall (NECWS) undergoes a remarkable interdecadal enhancement after 2001. Previous research confirmed that the relationship between the NTA SST anomaly and atmospheric circulation experienced interdecadal changes after the 2000s and suggested various reasons for this phenomenon. During 1961–2000, the NTA SST anomaly has a significantly positive correlation with other oceans, especially the tropical Indian Ocean (TIO), and the latter modulates the former’s impact on atmospheric circulations over the Eurasian continent with a cancelling effect, which results in a weaker relationship of the NTA SST anomaly and NECWS. In contrast, the warm NTA SST anomaly is relatively independent from other oceans during 2001–20, and it proves to be the forcing factor for NECWS since its solo influence on the winter atmospheric circulations initiated from the North Atlantic to East Asia is more robust, featuring the negative phase of the North Atlantic Oscillation and a downstream quasi-barotropic Rossby wave train over the mid- to high latitudes of Eurasian continent. Accordingly, together with the deepened East Asian trough and the strongly northward transported humid and warm air from the western Pacific, the local significantly enhanced ascending motions with cooling temperature favor much more NECWS. The linear baroclinic model simulates the effects of NTA and TIO SST anomalies on winter atmospheric circulations, corroborating the aforementioned results. Such results can be used for the prediction of NECWS with respect to the precursor of the autumn NTA SST anomaly.
Distributional Effects of Trade Liberalisation on Wages in India
Authors: Dhamija Nidhi 
Published: January 2023

There is a high level of policy interest on the effect of trade liberalisation on inequality, especially in developing countries, because of their large vulnerable populations. India also initiated the process of liberalisation as a response to the severe balance of payments crisis of 1991. However, both rural and urban inequality has been increasing since the period 1993–1994, with urban inequality increasing at a higher rate. This study empirically examines the impact of trade openness on wage inequality using panel data for Indian states (separately for rural and urban areas). The results of this study indicate that trade openness does not lead to decrease in the wage inequality in the states and their rural areas. However, urban wage inequality is found to be increasing due to trade openness. These results are analysed and explained by various factors present in the Indian economy such as, skill biased technological changes; trade in intermediate goods; barriers to domestic labour mobility; and pattern and composition of India’s exports. An interesting aspect emerging is that higher education levels lead to increase in wage inequality as returns to education and inequality are increasing and the increase is also attributed to liberalisation. JEL Codes: F16, O18, C23
Ageism and Type D Personality: The Protective Role of Self-Esteem and Perceived Social Support
Authors: Piterman David , Mazor Bar , Zohar Ada H. 
Published: January 2023

Background: This study examined the relationship between Type D personality and ageism in young adults, and evaluated the role of protective and risk factors. Methods: Two hundred and forty-seven community volunteers ( M age = 31.8 years) reported online on age-related attitudes, Type D personality, and on measures of well-being. Results: A significant correlation was found between ageist attitudes and the tendency toward Type D personality. Both Type D personality and ageism correlated negatively with all the well-being measures. Perceived social support (PSS) partially down-mediated the association between Type D personality and ageism. A three-way interaction was found among individuals with Type D personality. Low PSS and low self-esteem were associated with an elevation of ageism compared to those with low PSS and high self-esteem. Discussion: The current research suggests that self-esteem and PSS are protective against ageism, and might be good targets for psychological interventions in order to mitigate ageism, particularly among individuals with Type D personality.
Thyroid Abscess: A Case Series and Literature Review
Authors: Lesh Randy , Hellums Ryan , Pichardo Priscilla , Wong Jeff , Pellitteri Phillip , Purdy Nicholas , Stavrides Kevin , Haugen Thorsen W 
Published: January 2023

Objective In this retrospective case series, we chronicle six patients presenting with acute suppurative thyroiditis (AST) with progression to thyroid abscess in a single institution. Methods Patients ranged in age from 16 to 74 years of age. The most common presenting symptoms were progressive unilateral neck pain, swelling, and odynophagia. Other symptoms included hoarseness and systemic signs of infection. Diagnosis of thyroid abscess was made with a CT scan of the neck, fine needle aspiration, and/or incision and drainage (I&D). Results Management included antibiotic therapy, I&D, and thyroidectomy. All patients were successfully treated except for one who developed mediastinitis and died. Conclusion A complete literature review was performed to determine etiologies, common findings, and management of similar cases.