bluuebunny/crossref_metadata_2025_split huggingface dataset:
A REVIEW ON THE EFFECT OF SEASONS AND POLLUTION ON PLANKTON DIVERSITY IN INDIAN FRESHWATERS
Authors: RAHIM SAMIYA ABDUL , RADHIKA R. , MATHEW SOJOMON 
Published: July 2023

Plankton diversity serve as a good bio indicator of the overall health status of the water body. In most of the studies, the plankton diversity was found to be higher during pre monsoon and post monsoon seasons with comparison to monsoon season. These fluctuations are dependent on various environmental factors like pH, light, temperature, turbidity, salinity, dissolved oxygen content etc. Plenty of sunlight, temperature and clear water in pre monsoon and post monsoon seasons are significant reasons for plankton abundance. Monsoon season is characterized by inflow of water, nutrients, silt, and the resultant turbid waters will in turn prevent light penetration and affect the productivity of the aquatic ecosystem. During monsoon season, nutrients were washed off to the water bodies resulting in the diversity of planktons. In the review, it was noted that some planktons are sensitive whereas others are tolerant to environmental stress. Phytoplankton belonging to Cyanophyceae, Euglenophyceae, Chlorophyceae, Bacillariophyceae and Myxophyceae are predominantly seen on polluted waters indicating organic load and eutrophication, whereas zooplanktons like rotifers, copepods and calanoids are abundantly seen in most studies. This review deals with the studies done on plankton diversity with respect to degradation of water quality in freshwater bodies of India.
THE INTERNATIONAL EVENT “DAYS OF MOUNTAIN WATER”, TETEVEN, BULGARIA, MICROBIOLOGICAL AND PHYSICOCHEMICAL RESEARCH OF MOUNTAIN SPRING WATER
Authors: IGNATOV IGNAT , IGNATOV ALEXANDER I. , ANGELCHEVA MARIANA , ANGUSHEV IVAN 
Published: July 2023

In Bulgaria there are the following mountains – Stara Planina (Balkan), Rila, Pirin, Rodope etc. The name of the Balkan Peninsula is from the old name of the mountain Stara Planina – Balkan. In Bulagria there are 139 peaks more than 2000 m above sea level. The biggest peak in Balkan Peninsula is Mousala (2925 m). Teteven municipally has big part of Stara planina mountain with the highest peak Vezhen (2198 m).
The event “Days of mountain water” is one of a kind in Bulgaria. It takes place on 11th June and lasts for several days in the Municipality of Teteven, Bulgaria. Its beginning dates from 2010, and it is a joint undertaking between Ignat Ignatov, Scientific Research Center of Medical Biophysics and Municipality of Teteven, Bulgaria.
The event is connected with research of microbiological and physicochemical parameters of mountain spring waters from Municipality of Teteven, Bulgaria. The applied spectral method is „NES“. The analyses show the optimum quantity among the minerals of Calcium (Са2+), Magnesium (Mg2+), Potassium (K+), Sodium (Nа+), Manganese (Mn2+) and Zinc (Zn2+) that provide the right balance in the human body for health and longevity.
Considered is the history of the event and what is achieved by the organizers. The emphasis is on the main objectives set out by the event, and the accomplished tasks for its successful delivering. Representatives of 15 states have participated in it – Bulgaria, Austria, Germany, Switzerland, Russia, USA, France, Israel, Czech Republic, Denmark, Turkey, Greece, Hungary and Serbia.
A survey was conducted regarding the event “Days of mountain water” in the Facebook group “Teteven Balkan”. 66 people responded on a random basis. The aim of the survey was the people to estimate how useful stay in Teteven municipality is.
In the present article are listed in more detail the natural assets of municipal area of Teteven, located in “Fore-Balkan” in the central part of Stara planina Balkan range. The possibilities are shown for development of tourism in the region, its particular characteristics and specific features. Analyzed are the water resources, the mountain water as a factor for health and longevity. The information helps for development of tourism in the region. Described are the springs and fountains of mountain water in Teteven and its surrounding municipal areas. It is conducted quantitative and qualitative analysis of the chemical and physical parameters of the springs. On six of the springs are placed information signs about the chemical composition, physical parameters and properties relating to health.
A PRELIMINARY SURVEY OF HUMAN MORPHOGENETIC TRAITS WITH SIMPLE INHERITANCE PATTERNS IN GRADUATE STUDENTS OF SKR AND SKR GOVERNMENT COLLEGE FOR WOMEN, KADAPA, ANDHRA PRADESH, INDIA
Authors: DEVI P. SACHI , VANKARA ANU PRASANNA 
Published: July 2023

Many factors such as gene flow, genetic drift, migration, natural selection and temporal variation are responsible for the genetic variation in humans. The present pilot study was conducted to screen a random population of 194 female Indian graduate students for 13 different morphogenetic traits i.e., tongue rolling, tongue folding, polydactyly, hitchhiker's thumb, bent little finger, widow's peak, cleft chin, dimpled cheeks, mid-phalangeal hair, earlobe attachment, crossing of arms, right handedness and arched foot through questionnaires and datasheets. The prevalence of these morphogenetic traits was observed as dominant traits such as tongue rolling ability (75.3%) and tongue folding ability (96.4%), single-jointed hitchhiker’s thumb (76.3%), straight little finger (93.3%), free ear lobe (62.4%), arched foot (88.7%), right handedness (99%), right arm crossing over left arm (99.5%) etc. are expressed more recurrently in the population. However, recessive characters like absence of polydactyly (97.9%), absence of dimples (87.6%), absence of widow’s peak (77.8%), round chin (87.1%), absence of mid-phalangeal hair (77.1%), etc. are expressed more commonly in the population. We analyzed whether a trait is dominant or recessive. The survey result shows a disparity of this argument, it shows that some typical dominant character was not expressed but the expression of recessive character was prevalent as in the case of widow’s peak (absent), smooth chin, crossing of arms (right over left), Hitchhiker’s thumb (absent), absence of dimple, etc, all of which are recessive traits. Outcomes of this study can be suitable for many types of anthropological, medicolegal and population genetics studies.
EFFECT OF LEAD NITRATE ON HAEMOCYTE MORPHOLOGY OF FRESHWATER PRAWN, Macrobrachium dayanum (CRUSTACEA-DECAPODA)
Authors: TIWARI KUNWER JI , LODHI HARNAM SINGH , MISHRA ANAND , AHMAD AMAN , LODHI SAMIKSHA , SHUKLA SANJIVE 
Published: July 2023

Lead (Pb), a non-essential “Grey listed” heavy metal is a serious threat to aquatic flora and fauna. The haematological, nephrological, histopathological and neurological effects of lead are well known in vertebrates. Present study aims to investigate effect of lead on morphology of haemocytes, a important component of immune system of freshwater prawn, Macrobrachium dayanum. Prawns, collected at “Gulala-Ghat” from river Gomti, Lucknow, subjected to acute and sub-acute concentrations of lead nitrate (116.46 mg/l, 96h LC50; 29.12 mg/l, 25% of 96h LC50) showed morphological changes in haemocytes after 24, 48, 72 and 96h in acute exposure and after 10, 20 and 30 days in sub-acute exposure. The chief morphological changes like surface blebbing, vacuolization, cytoplasmic darkening, fragmentation of nuclear material, cone formation, nuclear pycnosis and breaking of plasma membrane were noticed after acute exposure (116.46 mg/litre). Black granular depositions, nuclear pycnosis and fragmentation of nuclear material; pseudopodial projections, blackening of the plasma membrane, achromatia were observed after sub-acute exposure (29.12 mg/litre). These changes were pronounced in prohaemocytes, granulocytes, plasmatocytes and spindle cells. The severity of morphological changes was dose- and duration-dependent. The present study found a positive correlation between heavy metal lead exposure and morphological changes in haemocyte morphology leading to severe immune dysfunction in freshwater prawn M. dayanum. This parameter can be used as bio-marker in health monitoring of prawns as well as environmental monitoring without sacrificing the animal.
ANTI-LEISHMANIAL ACTIVITY INVESTIGATION OF SOME NEW QUINAZOLINONE DERIVATIVES
Authors: FEROCHE ALEMU TADESSE , AWOKE DAGMAWIT , HAILU ASRAT 
Published: July 2023

In this study, some new 3-aryl, 2-substituted quinazoline-4 (3H) - one derivatives were synthesized using a three-step synthetic route. They were obtained in a good yield (59.5-85%) by applying different chemical reaction like cyclization and condensation reaction. The chemical structure of the final compounds was also verified by spectroscopic methods (IR, 1HNMR) and elemental microanalysis. The synthesized compounds (IVa, IVb, IVc, IVd, IVe and IVf) were screened for their in vitro anti-leishmanial activity against L. aethiopica isolate (CL/039/09). All tested compounds (IVa (0.03766 µg/ml), IVb (0.00538 µg/ml, IVc (0.00412 µg/ml, IVd (0.00110 µg/ml), IVe (0.03017 µg/ml) and IVf (0.03894 µg/ml)) showed excellent potency that is much better than the standard drug, amphotericin B (IC50 = 0.04359 ug/ml).
The results of acute toxicity indicated that all test compounds (IVa, IVb, IVc, IVd, IVe and IVf) proved to be non-toxic and well tolerated by the experimental animals up to 300 mg/kg in oral and 140 mg/kg in parental studies.
Behcet’s disease presenting with focal fibrosing mediastinitis and cava thrombosis; a case report with a review of the literature
Authors: Soran H. Tahira  , Fahmi H. Kakamad  , Dlsoz M. Hussein  , Shorsh A. Mohammed  , Rezheen J.  Rshid  , Karzan M. Salih  , Shvan H. Mohammed  , Hussein M. Hamasalih  , Abdulwahid M. Salih  
Published: July 2023

Introduction: Behcet's disease is a rare, multisystemic disease characterized by vasculitis and a triad of recurrent oral and genital mucosa ulcers with uveitis. Mediastinal fibrosis is extremely rare in Behcet's disease. The aim of this paper is to report a case of Behcet’s disease presenting as mediastinal fibrosis.
Case presentation: A 26-year-old male presented with a history of headaches and neck engorgement for a week duration. On physical examination, there were tender aphthous ulcers in the mouth, and one ulcer was also observed in the genitalia. Ultrasound of the neck revealed engorged internal jugular veins with a thrombus in the left one. Computed tomography confirmed the ultrasound findings. The patient was diagnosed with a case of Behcet’s disease. The patient was managed conservatively with Rivaroxaban, Prednisolone, and Ibuprofen.
Conclusion: Behcet's disease can cause mediastinal fibrosis in rare cases. Computed tomography is an efficient method for detecting mediastinal fibrosis and superior vena cava thrombosis.
Antropología Empalabramiento - Escritura Simbólica Hermenéutica: Atraso - Progreso Arquetipo Científico Afrodescendiente Venezolano
Authors: Gómez Romero Danny Francis 
Published: July 2023

La presente Investigación objeto de reflexión examinará los aportes que la misma hará en el campo del conocimiento a través del empalabramiento y la escritura en las concepciones de atraso - progreso en la ciencia afrodescendiente hoy venezolana que pueden apreciarse en la presencia de los negros, a diferencia de los indios, constituyó uno de los aportes predilectos de nuestra literatura. En este marco, la relevancia de esta investigación se centrará en escritos, perspectivas: Antropológicas, Epistemológica, Ontológica, Axiológica, otras. El entramado discursivo, será abordado con el método hermenéutico, histórico, y el método de investigación acción participante. Como posibles resultados: se interpretan los textos académicos literarios relacionados con el proceso de asimilación, integración, aculturación, transculturación, interculturación, posteriormente aportar reflexiones que coadyuven positivamente a la comprensión de la realidad afrodescendiente venezolana estudiada, de igual forma, se advierte la importancia del elemento femenino, tanto en el inconsciente colectivo como en la vida social
Projeto 120 telhados – inserção de micro-geração distribuída nas redes de baixa tensão: implantação de telhados solares em Sete Lagoas
Authors: De Souza Marcio Eli Moreira , Vale Maria Helena Murta , Chagas Eli Helberth Penido , Costa Suellen , Zilles Roberto 
Published: July 2023

Este artigo apresenta o processo de implantação do Projeto 120 Telhados na Cidade de Sete Lagoas – MG. O referido projeto é uma iniciativa da USP com recursos da FINEP que visa instalar 120 telhados divididos em 6 estados brasileiros com o objetivo de desenvolver competências em Geração Distribuída (GD) com sistemas fotovoltaicos conectados a redes elétricas de baixa tensão. Neste trabalho, são apresentados os resultados dos estudos de conexão dos sistemas fotovoltaicos no circuito de baixa tensão, extrapolando a condição proposta pelo projeto inicial, focando no comportamento do perfil de tensão de atendimento. Foram simulados diferentes cenários, considerando a localização física das GD’s em relação ao transformador de distribuição, a quantidade de GD’s presente no circuito, além da potência instalada individual.
IMPLEMENTASI FATWA DEWAN SYARIAH NASIONAL MUI NO. 108/DSN-MUI/X/2016 TENTANG PEDOMAN PENYELENGGARAAN PARIWISATA BERDASARKAN PRINSIP SYARIAH PADA BIRO PERJALANAN WISATA SYARIAH
Authors: Distianti Sheila , Ibadillah Muhammad Nazieh 
Published: July 2023

The development of sharia tourism which was currently becoming a trend had progressed in recent years to bring Indonesia to become the world's best sharia tourism destination in 2019. The development of sharia tourism was considered to provide positive progress for the economy, social and culture. This was also supported by the era of technology and socialization and expansion of sharia tourism by the travel agencies by packaging the many sharia tourism packages offered such as those in Elhasana Tour & Travel. And also various government regulations and the DSN-MUI fatwa issued in 2016 indicated that the government was serious in developing sharia tourism in Indonesia.
The purpose of this research was to determine the application of sharia principles in travel agencies in accordance with the DSN-MUI fatwa, to determine the driving factors and obstacles in the application of sharia principles in accordance with the DSN-MUI fatwa and to determine the effect of the application of sharia principles on business development in Elhasana Tour & Travel.
This research used structured observations, documentation, and interviews to obtain the desired information more accurately. The research used a qualitative method, which was descriptive in nature by producing a more in-depth description of the sharia travel agencies.
POLIGAMI Perspektif Hukum Islam dan Hukum Positif Hingga Teori Hudud Pemikiran Muhammad Syahrur
Authors: Nurjaman Amirudin , Sugianto Sugianto 
Published: July 2023

Praktek poligami dalam sejarah Islam memang telah ada, bahkan jumlah istri bisa lebih mencapai hingga belasan. Fakta ini membuktikan praktek poligami terus terpelihara hingga kini dengan berbagai pembenaran dan legitimasi baik budaya, sosial, ekonomi, dan agama. Bila melihat variabel tentang poligami dalam al-Qur'an, ada tiga poin penting yang dapat dibaca, pertama, memberikan kesempatan kepada suami untuk berpoligami. Kedua peringatan kepada suami untuk berlaku adil. Ketiga, adanya ketidakmampuan laki-laku untuk dapat berperilaku adil di antara istri-istrinya sekalipun telah diupayakan untuk itu. Ayat yang membolehkan pada konteksnya berbicara tentang perlindungan terhadap yatim piatu dan janda korban perang. Penelitian ini bersifat normatif, artinya mengkomparasikan pemaknaan POLIGAMI Perspektif Hukum Islam dan Hukum Positif Hingga Teori Hudud Pemikiran Muhammad Syahrur dalam rangka memberi solusi pemikiran yang berkembang saat ini. Penelitian ini menggunakan pendekatan legal and sociological normative approach, dengan analisis data kualitatif yang digunakan oleh peneliti dalam pemaparan hasil penelitian. Poligami pada dasarnya dibolehkan dalam Islam, namun memiliki aturan yang wajib dipatuhi yaitu: seorang suami boleh mengawini dengan perempuan yang disukai, yaitu empat orang istri, disamping itu wajib bersikap adil, dalam pemenuhan nafkah lahir maupun nafkah batin. Penulisan artikel ini bertujuan untuk mengetahui hukum berpoligami baik hukum islam maupun hukum positif di Indonesia. Untuk merespon tulisan ini disajikan teori hudud Muhammad Syahrur sebagai elemen ketiga atau jembatan dalam diskursus poligami. Teori ini sejenis proses desakralisasi yang memiliki maksud yang berbeda yang berlandaskan pada prinsip sabat al-nas wa harakat al-muhtawa.
Penerapan Machine Learning Dalam Pelayanan UPT BMKG Palembang di Bandara SMBII Palembang
Authors: Rizki Ramadhan Akbar , Deddy Kurniawan Desindra , Sutabri Tata 
Published: July 2023

BMKG Palembang merupakan salah satu Unit Pelaksana Teknis (UPT) BMKG pusat yang berada di daerah. Salah satu peran BMKG Palembang adalah memberikan pelayanan jasa meteorologi bagi masyarakat sumatera selatan khususnya Palembang. Ada beragam unsur meteorologi yang UPT BMKG Palembang layani yaitu curah hujan, durasi matahari, kecepatan dan arah angin, Tekanan serta temperatur dan kelembapan. Unsur meteorologi ini berperan penting dalam berbagai pelayanan masyarakat. Salah satunya dalam pelayanan aviasi (penerbangan) bagi pihak maskapai.dalam kajian ini, fokus unsur cuaca yang akan dibahas adalah curah hujan, temperatur dan kelembapan. Karena kedua unsur ini memberi pengaruh yang cukup signifikan terhadap unsur cuaca lainnya.analisis yang digunakan dalam kajian ini adalah metode regresi linier dengan algoritma machine learning dengan bahasa pemrograman python. Hasil dari penelitian adalah melihat korelasi variable unsur cuaca temperature terhadap variable curah hujan dan korelasi variable unsur cuaca kelembapan terhadap variable curah hujan. Dengan metode regresi linier didapati nilai dari korelasi variable temperature terhadap curah hujan adalah senilai - 0.32 dan nilai dari korelasi variable kelembapan terhadap curah hujan adalah senilai 0.68. berdasarkan hasil ini dapat disimpulkan bahwa antara temperature dan curah hujan memiliki keterikatan/korelasi negatif, yang berarti semakin tinggi nilai temperature maka nilai curah hujan akan semakin rendah, dan sebaliknya apabila semakin rendah temperature maka curah hujan akan semakin tinggi. Lalu variable unsur cuaca kelembapan terhadap curah hujan memiliki korelasi positif yang berarti setiap kenaikan nilai kelembapan maka naik juga nilai curah hujan, dan apabila nilai kelembapan turun maka turun juga nilai curah hujan. Dari hasil penelitian ini diharapkan dapat menjadi acuan UPT BMKG dalam melayani jasa informasi cuaca.
El Balance Social: Un modelo para la economía popular y solidaria del Ecuador
Authors: Páez Pareja José Ramón 
Published: July 2023

El presente trabajo muestra el desarrollo metodológico seguido hasta conseguir crear un nuevo modelo de Balance Social (BS). Este fue elaborado para la Superintendencia de Economía Popular y Solidaria del Ecuador (SEPS) como ente de supervisión y control de la economía popular y solidaria (EPS) del país, otorgándole una cuadruple funcionalidad: herramienta de control, de supervisión, de transparencia y de buen gobierno. Aunque es la propia Ley quien obliga a las organizaciones supervisadas a su elaboración y presentación ante el organismo de supervisión (SEPS).Metodológicamente conjuga el método inductivo con el deductivo y el analítico. Iniciándose el trabajo con una amplia revisión bibliográfica sobre las lógicas de funcionamiento de la economía social como subsistema de la economía mixta, sobre sus principios, así como sobre sus fundamentos. Todo ello posibilitó sentar las bases teóricas del modelo y con posterioridad proceder a su desarrollo, obteniendo finalmente una nueva metodología básica de Balance Social.Conjuntamente al citado desarrollo metodológico, el artículo presenta el modelo, su composición, así como su validación mediante pruebas piloto. Adicionalmente, si bien no forma parte del presente artículo, para el reporte de la información se desarrolló un aplicativo de carga de información y se realizó un primer requerimiento de la misma con el objetivo de levantar una línea base de cumplimiento normativo en materia de responsabilidad social por parte de las organizaciones supervisadas.
The prognostic significance of KLRB1 and its further association with immune cells in breast cancer
Authors: Xu Ning , Meng Xiangyu , Chu Hongyu , Yang Zhaoying , Jiao Yan , Li Youjun 
Published: July 2023

Background
Killer cell lectin-like receptor B1 (KLRB1) is an important member of the natural killer cell gene family. This study explored the potential value of KLRB1 as a breast cancer (BC) biomarker and its close association with the tumor immune microenvironment during the development of BC.

Methods
We examined the differential expression of KLRB1 in pan-cancer. Clinical and RNA-Seq data from BC samples were evaluated in The Cancer Genome Atlas (TCGA) and validated in Gene Expression Omnibus (GEO) datasets and by immunohistochemistry (IHC) staining. The relationship between KLRB1 and clinical parameters was explored through Chi-square tests. The diagnostic value of KLRB1 was evaluated using a receiver operating characteristic (ROC) curve. Survival analysis was tested by Kaplan-Meier curves to demonstrate the relationship between KLRB1 and survival. Univariable and multivariate cox regression analyses were carried out as well. The analysis of immune infiltration level and gene set enrichment analysis (GSEA) were conducted to examine KLRB1’s mechanism during the progression of BC. We used the Tumor Immune Estimation Resource (TIMER), the Cancer Single-cell Expression Map (CancerSCEM) database, the Tumor Immune Single-cell Hub (TISCH) database, and the Cell-type Identification by Estimating Relative Subsets of RNA Transcripts (CIBERSORT) method to explore KLRB1’s association with immune infiltration level and different quantitative distribution of immune cells. The relevant signaling pathways in BC associated with KLRB1 were identified using GSEA.

Results
The expression of KLRB1 was downregulated across the majority of cancers including BC. The lower KLRB1 expression group exhibited shorter relapse free survival (RFS) and overall survival (OS). IHC staining showed that KLRB1 staining was weaker in breast tumor tissues than in paratumors. Additionally, GSEA identified several pathway items distinctly enriched in BC. KLRB1 expression level was also positively related to the infiltrating number of immune cells in BC. Moreover, the CancerSCEM and TISCH databases as well as the CIBERSORT method demonstrated the close relationship between KLRB1 and immune cells, particularly macrophages.

Conclusion
Low KLRB1 expression was considered an independent prognostic biomarker and played an important role in the tumor immune microenvironment of BC patients.