bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does disc distraction after cervical total disc arthroplasty impact range of motion and patient-reported outcomes?
Authors: Federico Vincent P. , Zavras Athan G. , Nie James W. , Butler Alexander J. , Munim Mohammed A. , Nolte Michael T. , Lopez Gregory D. , An Howard S. , Colman Matthew W. , Phillips Frank M. 
Published: June 2023

OBJECTIVE
Total disc arthroplasty (TDA) has been established as a safe and effective alternative to anterior cervical discectomy and fusion for the treatment of cervical spine pathology. However, there remains a paucity of studies in the literature regarding the amount of disc height distraction that can be tolerated, as well as its impact on kinematic and clinical outcomes.

METHODS
Patients who underwent 1- or 2-level cervical TDA with a minimum follow-up of 1 year with lateral flexion/extension and patient-reported outcome measures (PROMs) were included. Middle disc space height was measured on preoperative and 6-week postoperative lateral radiographs to quantify the magnitude of disc space distraction, and patients were grouped into < 2-mm distraction and > 2-mm distraction groups. Radiographic outcomes included operative segment lordosis, segmental range of motion (ROM) on flexion/extension, cervical (C2–7) ROM on flexion/extension, and heterotopic ossification (HO). General health and disease-specific PROMs were compared at the preoperative, 6-week, and final postoperative time points. The independent-samples t-test and chi-square test were used to compare outcomes between groups, while multivariate linear regression was used to adjust for baseline differences.

RESULTS
Fifty patients who underwent cervical TDA at 59 levels were included in the analysis. Distraction < 2 mm was seen at 30 levels (50.85%), while distraction > 2 mm was observed at 29 levels (49.15%). Radiographically, after adjustment for baseline differences, C2–7 ROM was significantly greater in the patients who underwent TDA with < 2-mm disc space distraction at final follow-up (51.35° ± 13.76° vs 39.19° ± 10.52°, p = 0.002), with a trend toward significance in the early postoperative period. There were no significant postoperative differences in segmental lordosis, segmental ROM, or HO grades. After the authors controlled for baseline differences, < 2-mm distraction of the disc space led to significantly greater improvement in visual analog scale (VAS)–neck scores at 6 weeks (−3.68 ± 3.12 vs −2.24 ± 2.70, p = 0.031) and final follow-up (−4.59 ± 2.74 vs −1.70 ± 3.03, p = 0.008).

CONCLUSIONS
Patients with < 2-mm disc height difference had increased C2–7 ROM at final follow-up and significantly greater improvement in neck pain after controlling for baseline differences. Limiting differences in disc space height to < 2 mm affected C2–7 ROM but not segmental ROM, suggesting that less distraction may result in more harmonious kinematics between all cervical levels.
THE EFFECTIVENESS OF ETHANOL EXTRACT OF JAMBLANG LEAVES (Syzygium cumini L.) IN INCREASING HDL LEVELS IN WISTAR RATS MODELS OF METABOLIC SYNDROME
Authors: Muthmainah Muthmainah , Nurwati Ida , Handayani Selfi , Pakha Dyonisa Nasirochmi 
Published: June 2023

One of the characteristics of metabolic syndrome (MetS) is the low high-density lipoprotein (HDL) levels. Jamblang leaves (Syzygium cumini L.) contain various phytochemicals, which have antihyperglycemic, antihyperlipidemic, and antioxidant properties. This study aims to demonstrate the effectiveness of ethanol extract of jamblang leaves in increasing HDL levels in the Wistar rats model of MetS. A pretest-posttest with a control group design was conducted using 30 male Wistar rats, divided into five groups randomly, with six rats for each group.Â Here, KN means normal control group, K- negative control group, and P1, P2, and P3: treatment groups that were administered the 100 mg/kg/day, 150 mg/kg/day, and 200 mg/kg/day of ethanol extract of jamblang leaves for 28 days, respectively. The rat MetS model was developed by administering the high-fat fructose diet and streptozotocin-nicotinamide. The data were analyzed using paired t-test and one-way ANOVA (Î±=0.05). This study found that extract administration in P2 and P3 increased HDL levels significantly, but not with the P1 group. However, HDL levels in P1 were significantly higher compared to the K- group. Moreover, increasing the dose was significantly followed by higher HDL levels, although the highest dose did not reach the HDL level as in the KN group.
The problems of unifying information in the patient leaflets in Ukraine during the COVID-19 pandemic and wartime
Authors: Качерай Ю. В. , Заболотня З. О. , Заліська О. М. , Мудрак І. Г. , Кушта О. М. 
Published: June 2023

The information in the patient leaflets on the medicines must be unified, have a good structure and be clearly presented to the patient for prevent information asymmetry. We substantiated and worked a methodic of comparative analysis of antibiotic using for example of 74 instructions on the drug of one INN, which are registered on the markets of Ukraine, EU countries and Japan. Ways to unify information in to improve patient awareness of the correct use of drugs, especially antibiotics, are substantiated and presented.
Aim – to conduct a comparative analysis of the patient leaflets for antibacterial medicines and determine the presence or absence of information asymmetry using the example of antibiotics of one INN that are registrated on the Ukrainian market or they received as a humanitarian aid from Europe in wartime, in order to establish inconsistencies in the information structure and data in the information leaflets.
The objects were information leaflets for antibiotics: azithromycin, amoxiclav, amoxicillin, zinnate, cefazolin, cefatoxin. Methods were informational, comparative and content analysis. Methodology of information asymmetry analysis using the example of information leaflets for the medicine azithromycin from various manufacturers available on the market of Ukraine.
As a result, significant differences were established in 3 sections: «Indications», «Peculiarities of use», suspension preparation, etc. Significant differences were found in the information leaflets for prescribing azithromycin for skin infections, which requires immediate unification in the information leaflets of data for correct prescribing by a doctor using an electronic prescription and good use for a treatment course. It was established that in the for azithromycin from one manufacturer, which is on the market of Ukraine and EU countries, significant differences in information were found in 10 sections of the information leaflets, which requires the unification of information accordingly.
We have reasoned that the information leaflets should contain information that is important for the correct use of the medicine, in order to prevent potentially dangerous consequences that may arise from incorrect preparation or dosage. We grounded the information leaflets should include a section on the disposal of expired or unused medicines to harmonize with the information leaflets іn the EU countries.
The Standard Model Symmetry and Qubit Entanglement
Authors: Szangolies Jochen 
Published: June 2023

Research at the intersection of quantum gravity and quantum information theory has seen significant success in describing the emergence of spacetime and gravity from quantum states whose entanglement entropy approximately obeys an area law. In a different direction, the Kaluza-Klein proposal aims to recover gauge symmetries by means of dimensional reduction of higher-dimensional gravitational theories. Integrating both, gravitational and gauge degrees of freedom in \(3+1\) dimensions may be obtained upon dimensional reduction of higher-dimensional emergent gravity. To this end, we show that entangled systems of two and three qubits can be associated with \(5+1\) and \(9+1\) dimensional spacetimes respectively, which are reduced to \(3+1\) dimensions upon singling out a preferred complex direction. In the latter case, this reduction is invariant under a residual \(SU(3) \times SU(2) \times U(1) /\mathbb{Z}_6\) symmetry, the Standard Model gauge group. This motivates a picture in which spacetime emerges from the area law-contribution to the entanglement entropy, while gauge and matter degrees of freedom are due to area law-violating terms. We remark on a possible natural origin of the chirality of the weak force in the given construction.
Effect of daylight and air oxygen on nanozymatic activity of unmodified silver nanoparticles: Shelf-stability
Authors: Hormozi Jangi Saeed Reza 
Published: June 2023

In this work, unmodified silver nanoparticles were synthesized by a simple and cost-efficient method and then characterized by TEM imaging and UV-Vis. spectroscopy. Thereafter, their nanozymatic activity was investigated by catalyzing the oxidation of 3,3’,5,5’-tetramethyl-benzidine (TMB) as the standard peroxidase substrate. The results exhibited a specific activity as high as 5.4 µM min-1 for the as-prepared unmodified silver nanoparticles. Afterward, the effect of daylight and air oxygen on the peroxidase-like activity of these nanozymes was checked within 7 days. The results revealed that the activity of unmodified silver nanoparticles was approximately retained at about 75%, and 63% after 7 days exposing daylight and air oxygen, in order. The shelf-self of the as-prepared nanozymes was also investigated at 4 ℃ under dark conditions, revealed that these nanozymes saved about 96% of their initial activity after 10 days of storage at 4 ℃ under dark conditions.

KEYWORDS:Unmodified silver nanoparticles; Peroxidase-like nanozymes; Air oxygen; Daylight; Shelf-stability
ANALISIS PENDAPATAN USAHATANI KARET RAKYAT(Hevea brasiliensis Muell Arg)
Authors: Al Rasyid Harun 
Published: June 2023

Karet merupakan salah satu komoditas perkebunan dengan nilai ekonomis tinggi.Oleh karena itu, tidak salah jika banyak yang beranggapan bahwa tanaman karet adalah salah satu kekayaan Indonesia.Rendahnya produktivitas karet rakyat menyebabkan rendahnya produksi karet dan pendapatan dari usaha tani karet juga mempengaruhi rendahnya pendapatan rumah tangga petani sedangkan kebutuhan hidup petani tetap bahkan meningkat sehingga mendorong petani meningkatkan pendapatannya dengan melakukan eksploitasi penyadapan kurang baik dan berlebihan yang menyebabkan tanaman karet menjadi rusak.Penelitian ini dilakukan untuk menganalisis pendapatan petani karet rakyat.Untuk menganalisis kelayakan usahatani karet rakyat.Untuk mengetahui pola pemasaran karet rakyat yang ada di derah penelitian.Penelitian yang dilakukan ini berjenis penelitian kuantitatif dengan bentuk analisis dan subjek yang dijadikan sumber dalam penelitian ini adalah petani karet rakyat.Data yang digunakan adalah data primer dan sekunder. Metode analisis data menggunakan rumus pendapatan π = TR – TC dan rumus kelayakan R/C ratio dan untuk mengetahui pola pemasaran karet rakyat dilakukan secara deskriptif yaitu hanya melihat pola pemasaran yang terjadi di Kelurahan Simangambat Kecamatan Siabu Kabupaten Mandailing Natal. Hasil penelitian menunjukkan bahwa keuntungan petani karet rakyat di daerah penelitian sebesar Rp. 56.475.766 /tahun.Usahatani karet rakyat layak untuk diusahakan di daerah penelitian dikarenakan nilai R/C Rasio yang di peroleh lebih besar dari satu (R/C Rasio > 1). Dengan nilai 4,81> 1, maka dikatakan bahwa usahatani karet rakyat layak di usahakan di Kelurahan Simangambat Kecamatan Siabu Kabupaten Mandailing Natal, walaupun dengan keterbatasan modal yang dimiliki petani akibat menurunnya harga karet yang cukup drastis.Rantai pemasaran karet rakyat di daerah penelitian Petani menjual karetnya ke Pedagang Pengumpul Desa (Agen) dan selanjutnya menjualnya ke Pabrik Industri pengolahan karet
Edukasi, Komunikasi dan Informasi Kesehatan Reproduksi Perempuan bagi Kelompok Dharma Wanita Persatuan BPDASHL Benain Neolmina Kota Kupang
Authors: Saleh Ummi Kaltsum S , Bakoil Mareta Bakale 
Published: June 2023

ABSTRAK Masalah yang berhubungan dengan kesehatan reproduksi wanita di Indonesia semakin hari semakin komplek. Banyaknya kasus kematian ibu karena kanker serviks, kanker payudara, dan tingginya kasus HIV/AIDS di Kota Kupang menimbulkan kekhawatiran bagi kelompok dharma wanita persatuan BPDASHL Benain Neolmina Kota Kupang. Kegiatan yang dilakukan adalah pemberian edukasi dan informasi kepada kelompok ibu-ibu Dharma Wanita Persatuan BPDASHL Benain Neolmina Kota Kupang tentang kesehatan reproduksi perempuan, organ reproduksi, masalah kesehatan reproduksi perempuan, pencegahan dan cara merawat organ reproduksi. Kegiatan diikuti oleh 15 orang ibu. Kegiatan pengabdian masyarakat yang dilakukan kepada kelompok ibu-ibu Dharma Wanita Persatuan BPDASHL Benain Neolmina Kota Kupang menunjukkan capaian keberhasilan dengan adanya peningkatan pengetahuan dan pemahaman tentang kesehatan reproduksi. Penambahan pengetahuan dan pemahaman tentang kesehatan reproduksi menyebabkan ibu-ibu lebih mudah dalam memberikan upaya preventif dan upaya kuratif lebih dini bila diperlukan. Kata Kunci: Kesehatan, Reproduksi, Perempuan ABSTRACT The women's reproductive health problems in Indonesia are increasingly complex. The number of maternal deaths cases due to cervical cancer, breast cancer, and the high number of HIV/AIDS in Kupang City has raised concerns to Dharma Wanita BPDASHL Benain Neolmina, Kupang City. The activites were informed about woman reproductive health, reproductive system, reproductive health problems, prevention and woman reproductive health care. The activity was attended by 15 participant. Through this activities increase their knowledge about reproductive health. It showed success with understanding of reproductive health. The addition of knowledge and understanding of reproductive health makes easier for women to prevent reproductive health problems and if needed, curative efforts can be obtained earlier. Keywords : Health, Reproductive, Woman
Pemberdayaan Kader dalam Meningkatkan Status Vaksinasi Covid 19 Ibu Hamil di Puskesmas Sorong Timur
Authors: Situmorang Cory Chorajon , Pongoh Ariani 
Published: June 2023

ABSTRAK Pada tahun 2021 tercatat kurang dari 5% ibu hamil yang melakukan vaksinasi covid 19 di wilayah kerja Puskesmas Sorong Timur Kota Sorong. Untuk meningkatkan pengetahuan dan menyebarkan informasi tentang cara pencegahan Covid 19 dibutuhkan peran media sebagai sumber informasi dan kader posyandu sebagai mitra tenaga Kesehatan yang dekat dengan ibu hami. Pengabdian dilakukan pada 6 orang kader dan 19 ibu hamil trimester II dan 3 di Kelurahan Kladufu, Puskesmas Sorong Timur Kota Sorong. Pengabdian dilakukan dengan cara melakukan edukasi dan pelatihan kepada kader posyandu terkait vaksinasi Covid 19 pada ibu hamil dengan alat bantu buku saku. Kader melakukan pendampingan kepada ibu hamil yang belum melakukan vaksinasi mulai dari trimester II (> 14 Minggu sampai vaksinasi kedua). Untuk mengetahui keberhasilan kegiatan dilakukan evaluasi terkait pengetahuan kader dan status vaksinasi ibu hamil. Hasil Pengabdian diperoleh sebelum dilakukan pelatihan paling banyak kader memiliki pengetahuan kurang yaitu 5 orang (71,4%) sedangkan setelah dilakukan pelatihan paling banyak kader memiliki pengetahuan baik yaitu 6 orang (85,7%). Pada ibu hamil, sebelum dilakukan pendampingan paling banyak ibu hamil dengan status vaksinasi covid 19 tidak lengkap yaitu 19 (100%) sedangkan setelan dilakukan pendampingan kader paling banyak ibu hamil dengan status vaksinasi covid 19 lengkan yaitu 17 orang (89,5%). Kata Kunci: Vaksinasi Covid 19, Ibu Hamil ABSTRACT In 2021 it was recorded that less than 5% of pregnant women vaccinated against COVID-19 in the working area of the East Sorong Community Health Center, Sorong City. To increase knowledge and disseminate information about how to prevent Covid 19, the role of the media as a source of information and posyandu cadres are needed as partners for health workers who are close to pregnant women. The service was carried out on 6 cadres and 19 pregnant women in the second and third trimesters in Kladufu Village, East Sorong Health Center, Sorong City. This service is carried out by providing education and training to posyandu cadres regarding the Covid 19 vaccination for pregnant women using pocket books and leaflet. Cadres provide assistance to pregnant women who have not vaccinated starting from the second trimester (> 14 weeks until the second vaccination). To determine the success of the activity, an evaluation was carried out regarding the knowledge of cadres and the vaccination status of pregnant women. The results of the service obtained before the training was carried out that most cadres had less knowledge, namely 5 people (71.4%) while after training, most cadres had good knowledge, namely 6 people (85.7%). For pregnant women, before mentoring was carried out, the most pregnant women with incomplete COVID-19 vaccination status was 19 (100%) while the setting was assisted by cadres, mostly pregnant women with COVID-19 vaccination status, namely 17 people (89.5%). Keywords: Covid 19 Vaccination, Pregnant Women
Asuhan Keperawatan Komprehensif pada Penderita Asam Urat dengan Masalah Nyeri Menggunakan Kompres Jahe Hangat di Wilayah Kerja Puskesmas Karang Anyar Bandar Lampung
Authors: Caesarani Ananda Donna , Kn Idawati , Zainaro M. Arifki 
Published: June 2023

ABSTRAK Penyakit asam urat muncul sebagai akibat dari kondisi hiperurisemia ini. Berdasarkan data dari Puskesmas Karang Anyar Bandar Lampung tahun 2022 dari bulan Januari sampai bulan April di ketahui bahwa kasus asam urat yang terjadi pada lansia ada 91 kasus. Salah satu bahan untuk kompres yang dapat memberikan sensasi hangat adalah jahe. Kandungan jahe bermanfaat untuk mengurangi nyeri pada asam urat karena jahe memiliki sifat pedas, pahit dan aromatik dari olerasin seperti zingeron, gingerol, dan shagaol. Melakukan analisa jurnal, penerapan intervensi jurnal, pembahasan hasil asuhan keperawatan asuhan keperawatan komprehensif dengan kompres jahe hangat terhadap nyeri pada penderita asam urat di Wilayah Kerja Puskesmas Karang Anyar Bandar Lampung. Desain student oral case analysis (SOCA) menggunakan desain studi kasus dalam bentuk penerapan dengan cara pendekatan sesuai metode deskriptif, metode ini bersifat mengumpulkan data terlebih dahulu, menganalisis data lalu menarik kesimpulan data. Unit yang menjadi kasus tersebut secara lebih jauh dianalisis dan diberikan suatu tindakan terapi. Dalam asuhan keperawatan ini ada 3 pasien yaitu Ny.B, Ny.M dan Tn.M mengalami penurunan nyeri setelah diberikan kompres jahe hangat. Asuhan keperawatan yang dilakukan terhadap Ny.B, Ny.M dan Tn.M yaitu memberikan kompres jahe hangat untuk menurunkan nyeri. Kata Kunci: Asam Urat, Kompres Jahe Hangat, Nyeri ABSTRACT Gout appears as a result of this hyperuricemia condition. Based on data from the Karang Anyar Health Center in Bandar Lampung in 2022 from January to April, it is known that there were 91 cases of gout that occurred in the elderly. One of the ingredients for compresses that can give a warm sensation is ginger. The content of ginger is useful for reducing pain in gout because ginger has spicy, bitter and aromatic properties from olerasin such as zingeron, gingerol, and shagaol. Analyze journals, apply journal interventions, discuss results nursing care comprehensive nursing care with warm ginger compresses for pain in gout sufferers in the Working Area of the Karang Anyar Health Center, Bandar Lampung. The student oral case analysis (SOCA) design uses a case study design in the form of application by means of an approach according to the descriptive method, this method is to collect data first, analyze the data and then draw conclusions on the data. The unit that became the case was further analyzed and given a therapeutic measure. In this nursing care, there were 3 patients, namely Mrs.B, Mrs.M and Mr.M, who experienced a decrease in pain after being given warm ginger compresses. Nursing care was carried out for Mrs.B, Mrs.M and Mr.M, namely giving warm ginger compresses to reduce pain. Keywords: Gout, Warm Ginger Compress, Pain
Penerapan Pekar (Peningkatan Pengetahuan Kesehatan Keluarga) di Kelurahan Kayuringin Jaya Bekasi Selatan
Authors: Listiyorini Meria Woro , Iksan Ricky Riyanto , Harini Rika , Sunirah Sunirah , Ponirah Ponirah , Batubara Salama Thomasita 
Published: June 2023

ABSTRAK Program Indonesia Sehat (PIS) merupakan salah satu program dari Agenda ke-5 Nawa Cita, yaitu meningkatkan Kualitas Hidup Manusia Indonesia, dengan sasaran meningkatnya derajat kesehatan dan status gizi masyarakat. Tujuan pengabdian kepada masyarakat ini adalah untuk meningkatkan pengetahuan ibu-ibu di lingkungan RW 024 Kelurahan Kayuringin Jaya agar dapat menjaga, meningkatkan dan memelihara Kesehatan keluarganya. Metode yang digunakan berupa penyuluhan Kesehatan yang dilakukan dengan bantuan leaflet serta metode ceramah, tanya jawab serta diskusi. Dari 65 peserta yang hadir pada penyuluhan seperti stakeholder RW 024 Kelurahan Kayuringin Jaya, sebelum dilakukan penyuluhan peserta telah mengetahui tentang Kesehatan reproduksi, perubahan memasuki masa usia lanjut, kebutuhan istirahat dan tidur dan tata laksana tidur ala Rasulullah, kesehatan pada usia lanjut dan tips bahagia diusia lanjut dan Melatih senam relaksasi otot prograsif pada usia lanjut. Kegiatan penyuluhan ini berjalan kondusif disebabkan peserta memperhatikan materi yang disampaikan oleh penyaji dengan baik. Kata Kunci: PIS, Penyuluhan Kesehatan, Senam Otot Progresif,Lansia ABSTRACT The Healthy Indonesia Program (PIS) is one of the programs from the 5th Nawa Cita Agenda, which is to improve the Quality of Life of Indonesian Humans, with the aim of increasing the health status and nutritional status of the community. The purpose of this community service is to increase the knowledge of mothers in the RW 024 Kelurahan Kayuringin Jaya so that they can maintain, improve and maintain the health of their families. The method used is in the form of health counseling which is carried out with the help of leaflets as well as lecture, question and answer and discussion methods. Of the 65 participants who attended the counseling such as the stakeholders of RW 024 Kelurahan Kayuringin Jaya, before the counseling was carried out the participants already knew about reproductive health, changes in entering old age, the need for rest and sleep and sleep management a la Rasulullah, health in old age and tips happy in old age and practicing progressive muscle relaxation gymnastics in old age. This counseling activity was conducive because the participants paid attention to the material presented by the presenter properly. Keywords: PIS, Health Education, Progressive Muscle Exercise, The Elderly