bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Penambahan Slot Terhadap Kinerja Antena WLAN
Authors: Charisma Atik , Pratama Reja , Rusiana Iskandar Handoko , Haz Fauzia 
Published: June 2023

Salah satu perangkat yang berperan penting pada kinerja Wireless LAN (WLAN) adalah antena. Antena microstrip umumnya digunakan pada perancangan teknologi dengan frekuensi tinggi. Oleh karena itu cocok untuk meningkat kinerja WLAN yang bekerja di frekuensi 2,4 GHz. Pada penelitian ini menambahan slot pada antena untuk meningkatkan kinerja WLAN. Antena susun 2x1 yang dirancang bekerja pada frekuensi WLAN yakni 2,4 GHz. Gain yang dihasilkan antenna ini sebesar 3,8 dB yang sangat berpengaruh pada penguatan sinyal antena WLAN.
A Collaborative Graph-based SLAM Framework Using a Computationally Effective Measurement Algebra
Authors: Péter Gábor , Kiss Bálint 
Published: June 2023

Simultaneous localization and mapping (SLAM) is an essential task for autonomous rover navigation in an unknown environment, especially if no absolute location information is available. This paper presents a computationally lightweight framework to enable agents with limited processing power to carry out the SLAM cooperatively and without absolute onboard localization sensors in a 2D environment. The proposed solution is built on a graph-based map representation, where nodes (resp. edges) represent landmarks (resp. odometry-based relative measurements), a measurement algebra with embedded uncertainty, and a compact database format that could be stored on a server in a centralized manner. The operations required by the agents to insert a new landmark in the graph, update landmark positions and combine measurements as a loop is closed in the graph are detailed. The resulting framework was tested in a laboratory environment and on a public dataset with encouraging results; hence our method can be used for cost-effective indoor mobile agents with limited computational resources and onboard sensors to achieve a mapping while keeping track of the agent's position. The method can also be easily generalized for a 3D scenario.
Kajian Komposisi Bahan Tambahan Pangan Pada Produk Daging Ayam Olahan Komersial
Authors: Arzani Lalu Danu Prima , Utama Qabul Dinanta 
Published: June 2023

Tujuan penelitian ini adalah mengidentifikasi komposisi bahan tambahan pangan yang terdapat pada produk daging ayam olahan komersial berdasarkan regulasi di Indonesia. Sampel yang dinilai berjumlah 47 berbagai produk daging ayam olahan komersial, BTP yang diamati adalah penguat rasa, pengemulsi, pengawet, penstabil, antioksidan, pengatur keasaman, pengembang dan pewarna. BTP yang digunakan dalam produk bakso ayam adalah penguat rasa (42,86%), pengemulsi (4.76%), penstabil (23,81%) dan pengatur keasaman (28,57%) Pada produk sosis ayam adalah penguat rasa (23%), penstabil (23%), antioksidan (17%), pengemulsi (3%), pengawet (15%), pengatur keasaman (12%) dan pewarna (7%). Pada produk siomay ayam adalah pengatur keasaman (40%), penguat rasa (20%), penstabil (20%), pengawet (13%), dan pewarna (7%). Pada produk naget ayam adalah pewarna (26%), penguat rasa (22%), penstabil (18%), antioksidan (11%), pengemulsi (11%) pengawet (7%), pengemban (2%) dan pengatur keasaman (2%). Pada produk daging ayam olahan kategori 08.2.3. adalah penstabil (21.54%), penguat rasa (33.85%), pewarna (18.46%), pengawet (10,77%), antioksidan (7,69%) dan pengembang (7,69%). Penggunaan BTP dan juga jumlah konsumsi produk yang mengandung BTP terutama BTP yang memiliki risiko karsinogenik perlu menjadi perhatian pemerintah untuk diregulasi dan juga para konsumen. Penelitian di masa depan untuk menemukan alternatif yang lebih aman untuk BTP ini sangat dianjurkan.
Palliative primary tumor resection in minimally symptomatic (asymptomatic) patients with colorectal cancer and synchronous unresectable metastases versus chemotherapy alone: a metaanalysis
Authors: Alimova Iu. V. , Shelygin Yu. A. , Rybakov E. G. , Alekseev M. V. 
Published: June 2023

AIM: to evaluate outcomes (overall survival, rate of surgical intervention due to complications of first treatment, 30-day mortality rate) of palliative primary tumor resection (PTR) followed by chemotherapy and chemotherapy/ radiotherapy (chemo/RT) alone in patients with asymptomatic or minimally symptomatic colorectal cancer (CRC) and synchronous unresectable metastases.MATERIALS AND METHODS: a meta-analysis based on Preferred Reporting Items for Systematic Reviews and Metaanalyses (PRISMA) guidelines was conducted on PubMed and Cochrane database. Odds ratio (OR) and 95% confidence interval (95% CI) were used as the treatment effect measure for comparing results. Combined overall effect measures were calculated for a random effect model. All analyses were performed using the Review Manager 5.3 software.RESULTS: eighteen non-randomized studies, including a total of 2,999 patients (1,737 PTR and 1,262 chemo/RT) were identified. Gender, age, site of primary tumor and distant metastasis of patients were comparable between groups in all analyzed studies. Two-year (38.2% vs. 21.1%; OR 0.42; 95% CI 0.28–0.64; p < 0.0001) and 5-year (12.7% vs. 5.3%; OR 0.45; 95% CI 0.21–0.97; p = 0.04) overall survival rates were significantly higher in the PTR group than in the chemo/RT group. No significant differences in 30-day mortality rate between the two groups (1.7% vs. 1%; OR 1.92; 95% CI 0.79–4.68; p = 0.15). However, the rate of surgical intervention due to complications of first treatment was significantly lower in the PTR group comparing to the chemo/RT group (2.3% vs. 14.53%; OR 0.18; 95% CI 0.08–0.40; p < 0.0001). At the same time, one hundred and fourteen patients (13.8%; OR 0.19; 95% CI 0.09–0.40; p < 0.0001) in the chemo/RT group required surgery for symptoms associated with a primary tumor.CONCLUSIONS: PTR in patients with asymptomatic or minimally symptomatic CRC and synchronous unresectable metastases significantly improves overall survival, allows to prevent surgical intervention due to complications related to primary tumor and is not associated with increased postoperative mortality rate comparing to systemic chemotherapy/radiotherapy as a treatment of first line. The current data are based on non-randomized comparative studies and data from early terminated randomized controlled trials (RCTs) and further well-designed RCTs are required.
Consensus on controversial issues of the surgery for Crohn’s disease by Delphi method
Authors: Shelygin Yu. A. , Achkasov S. I. , Reshetov I. V. , Mayev I. V. , Drapkina O. M. , Belousova E. A. , Vardanyan A. V. , Nanaeva B. A. , Abdulganieva D. I. , Adamyan L. V. , Namazova-Baranova L. S. , Razumovsky A. Yu. , Revishvili A. Sh. , Khatkov I. E. , Shabunin A. V. , Livzan M. A. , Sazhin A. V. , Timerbulatov V. M. , Khlynova O. V. , Yatsyk S. P. , Abdulkhakov R. A. , Alekseeva O. P. , Alekseenko S. A. , Bakulin I. G. , Barysheva O. Yu. , Blagovestnov D. A. , Bolikhov K. V. , Veselov V. V. , Vinogradov Yu. A. , Golovenko O. V. , Gubonina I. V. , Gulyaev A. A. , Dolgushina A. I. , Dyakonova E. Yu. , Zhigalova T. N. , Karpukhin O. Yu. , Knyazev O. V. , Kostenko N. V. , Loranskaya I. D. , Moskalev A. I. , Odintsova A. H. , Omelyanovsky V. V. , Osipenko M. F. , Pavlenko V. V. , Poluektova E. A. , Popov D. E. , Rodoman G. V. , Segal A. M. , Sitkin S. I. , Skalinskaya M. I. , Surkov A. N. , Tarasova L. V. , Uspenskaya Yu. B. , Frolov S. A. , Chashkova E. Yu. , Shapovalyants S. G. , Shifrin O. S. , Shcherbakova O. V. , Shchukina O. B. , Shkurko T. V. , Nazarov I. V. , Mingazov A. F. 
Published: June 2023

AIM: to establish the consensus on controversial issues of the surgery for Сrohn’s disease by Delphi method.METHODS: a cross-sectional study was conducted by the Delphi method. 62 experts voted intramural and anonymous (31.03.23). 5 statements from the current edition of clinical guidelines were selected for correction by working group and further voting [2]. Based on the practical experience of the working group and literature data, 3 new statements were created also. Statements that do not reach the required level of agreement (80% or more) will be subjected to Round 2 of the Delphi method.RESULTS: all experts took part in the anonymous voting. The panel of experts is represented by 8 different areas of practical medicine and the median of the professional experience of the respondents was 30 (12–49) years. Of the 8 statements submitted for voting, consensus (80% or more) was reached on 6 out of 8. 2 statements have been revised by working group for the distance 2nd round of the Delphi study. Consensus (more than 80%) was reached on both.CONCLUSION: a cross-sectional study by the Delphi method provided the opinions of a panel of experts on controversial issues in the surgical treatment of Crohn’s disease. Statements that reach consensus will be included by the working group in a new edition of clinical guidelines of Crohn’s disease.
Effectiveness of minimally invasive and surgical methods of treatment of chronic hemorrhoids using phlebotonics
Authors: Belik B. M. , Kovalev A. N. 
Published: June 2023

PURPOSE: to evaluate the effect of phlebotropic therapy on the effectiveness of surgical treatment of hemorrhoids.PATIENTS AND METHODS: a comparative evaluation of the results of treatment of 406 patients with chronic hemorrhoids of stages III and IV was performed. With surgical treatment of hemorrhoids, standard conservative therapy was performed in 205 patients (group I) and 201 patients (group II) in the perioperative period, as well as at the rehabilitation stage, the standard program of drug treatment was supplemented with phlebotropic therapy using Detralex (1000 mg).RESULTS: in group II patients, compared with group I patients, pain syndrome was stopped faster, quality of life and working capacity were restored, and the period of epithelization of the anal canal wound was shortened (21.4 ± 1.7 days versus 26.8 ± 2.1 days). This made it possible to increase the number of good and satisfactory results of surgical treatment of hemorrhoids from 82.4% to 91.5%.CONCLUSION: outpatient surgical treatment of hemorrhoids of stages III-IV in combination with phlebotropic therapy can reduce the number of postoperative complications from 17.6% to 8.5% and increase the overall number of good and satisfactory treatment results from 82.4% to 91.5% (p < 0.005).
Screening for colorectal cancer in employees of ROSTEСH enterprises in the Sverdlovsk region. Pilot project
Authors: Desyatov E. N. , Aliev F. Sh. , Tsvetkov M. S. , Verkhovodova I. S. , Yakovleva I. L. 
Published: June 2023

AIM: to evaluate the pilot program results for colorectal cancer (CRC) screening of the Sverdlovsk region (April — October 2021)PATIENTS AND METHODS: a pilot program of three-stage CRC screening included at the first stage, the fecal immunochemical test was performed (patients aged 45–65 years). The second stage included questionnaire. According to the results of the questioning, patients with a positive fecal test and a potential risk of CRC underwent colonoscopy at the third stage.RESULTS: at the first and second stages, 969 fecal immunochemical tests and questionnaires were performed. In 149 (15.4%) cases, a positive fecal test was detected. In 22 cases, employees with a negative fecal test were referred for colonoscopy according to the results of the questionnaire. At the third stage, 168 screening colonoscopies were performed. In 87 (51.5%) patients, epithelial colorectal neoplasia was detected, adenoma — in 57 (33.7%) cases, adenocarcinoma in 4 (2.4%), including T0 — in 3 patients, T2 — in 1 patient. In 182 cases, neoplasia occurred in 17.6% in the rectum and in 82.4% in the colon.CONCLUSION: colorectal cancer (CRC) screening showed high efficacy.
Does a novel bridging collar in endoprosthetic replacement optimise the mechanical environment for osseointegration? A finite element study
Authors: Fraterrigo Giulia , Schileo Enrico , Simpson David , Stevenson Jonathan , Kendrick Ben , Taddei Fulvia 
Published: June 2023

Introduction: Limb-salvage surgery using endoprosthetic replacements (EPRs) is frequently used to reconstruct segmental bone defects, but the reconstruction longevity is still a major concern. In EPRs, the stem-collar junction is the most critical region for bone resorption. We hypothesised that an in-lay collar would be more likely to promote bone ongrowth in Proximal Femur Reconstruction (PFR), and we tested this hypothesis through validated Finite Element (FE) analyses simulating the maximum load during walking.Methods: We simulated three different femur reconstruction lengths (proximal, mid-diaphyseal, and distal). For each reconstruction length one in-lay and one traditional on-lay collar model was built and compared. All reconstructions were virtually implanted in a population-average femur. Personalised Finite Element models were built from Computed Tomography for the intact case and for all reconstruction cases, including contact interfaces where appropriate. We compared the mechanical environment in the in-lay and on-lay collar configurations, through metrics of reconstruction safety, osseointegration potential, and risk of long-term bone resorption due to stress-shielding.Results: In all models, differences with respect to intact conditions were localized at the inner bone-implant interface, being more marked in the collar-bone interface. In proximal and mid-diaphyseal reconstructions, the in-lay configuration doubled the area in contact at the bone-collar interface with respect to the on-lay configuration, showed less critical values and trends of contact micromotions, and consistently showed higher (roughly double) volume percentages of predicted bone apposition and reduced (up to one-third) percentages of predicted bone resorption. In the most distal reconstruction, results for the in-lay and on-lay configurations were generally similar and showed overall less favourable maps of the bone remodelling tendency.Discussion: In summary, the models corroborate the hypothesis that an in-lay collar, by realising a more uniform load transfer into the bone with a more physiological pattern, creates an advantageous mechanical environment at the bone-collar interface, compared to an on-lay design. Therefore, it could significantly increase the survivorship of endo-prosthetic replacements.
An ex vivo preliminary investigation into the impact of parameters on tissue welding strength in small intestine mucosa-mucosa end-to-end anastomosis
Authors: Zhu Caihui , Yin Li , Xu Jianzhi , Liu Haotian , Xiang Xiaowei , Zhao Hui , Qiu Jian , Liu Kefu 
Published: June 2023

Background: Tissue welding is an electrosurgical technique that can fuse tissue for small intestine anastomosis. However, limited knowledge exists on its application in mucosa-mucosa end-to-end anastomosis. This study investigates the effects of initial compression pressure, out-put power, and duration time on anastomosis strength ex vivo in mucosa-mucosa end-to-end anastomosis.Methods:Ex vivo porcine bowel segments were used to create 140 mucosa-mucosa end-to-end fusions. Different experimental parameters were employed for fusion, including initial com-pression pressure (50kPa–400 kPa), output power (90W, 110W, and 140W), and fusion time (5, 10, 15, 20 s). The fusion quality was measured by burst pressure and optical microscopes.Results: The best fusion quality was achieved with an initial compressive pressure between 200 and 250 kPa, an output power of 140W, and a fusion time of 15 s. However, an increase in output power and duration time resulted in a wider range of thermal damage. There was no significant difference between the burst pressure at 15 and 20 s (p &gt; 0.05). However, a substantial increase in thermal damage was observed with longer fusion times of 15 and 20 s (p &lt; 0.05).Conclusion: The best fusion quality for mucosa-mucosa end-to-end anastomosis ex vivo is achieved when the initial compressive pressure is between 200 and 250 kPa, the output power is approximately 140W, and the fusion time is approximately 15 s. These findings can serve as a valuable theoretical foundation and technical guidance for conducting animal experiments in vivo and subsequent tissue regeneration.
Evaluation of silver bio-functionality in a multicellular in vitro model: towards reduced animal usage in implant-associated infection research
Authors: Cecotto Leonardo , Stapels Daphne A. C. , van Kessel Kok P. M. , Croes Michiel , Lourens Zeldali , Vogely H. Charles , van der Wal Bart C. H. , van Strijp Jos A. G. , Weinans Harrie , Amin Yavari Saber 
Published: June 2023

BackgroundDespite the extensive use of silver ions or nanoparticles in research related to preventing implant-associated infections (IAI), their use in clinical practice has been debated. This is because the strong antibacterial properties of silver are counterbalanced by adverse effects on host cells. One of the reasons for this may be the lack of comprehensive in vitro models that are capable of analyzing host-bacteria and host-host interactions.Methods and resultsIn this study, we tested silver efficacy through multicellular in vitro models involving macrophages (immune system), mesenchymal stem cells (MSCs, bone cells), and S. aureus (pathogen). Our model showed to be capable of identifying each element of culture as well as tracking the intracellular survival of bacteria. Furthermore, the model enabled to find a therapeutic window for silver ions (AgNO3) and silver nanoparticles (AgNPs) where the viability of host cells was not compromised, and the antibacterial properties of silver were maintained. While AgNO3 between 0.00017 and 0.017 µg/mL retained antibacterial properties, host cell viability was not affected. The multicellular model, however, demonstrated that those concentrations had no effect on the survival of S. aureus, inside or outside host cells. Similarly, treatment with 20 nm AgNPs did not influence the phagocytic and killing capacity of macrophages or prevent S. aureus from invading MSCs. Moreover, exposure to 100 nm AgNPs elicited an inflammatory response by host cells as detected by the increased production of TNF-α and IL-6. This was visible only when macrophages and MSCs were cultured together.ConclusionsMulticellular in vitro models such as the one used here that simulate complex in vivo scenarios can be used to screen other therapeutic compounds or antibacterial biomaterials without the need to use animals.
Trends in worldwide research on cardiac fibrosis over the period 1989–2022: a bibliometric study
Authors: Mao Yukang , Fu Qiangqiang , Su Feng , Zhang Wenjia , Zhang Zhong , Zhou Yimeng , Yang Chuanxi 
Published: June 2023

BackgroundCardiac fibrosis is a hallmark of various end-stage cardiovascular diseases (CVDs) and a potent contributor to adverse cardiovascular events. During the past decades, extensive publications on this topic have emerged worldwide, while a bibliometric analysis of the current status and research trends is still lacking.MethodsWe retrieved relevant 13,446 articles on cardiac fibrosis published between 1989 and 2022 from the Web of Science Core Collection (WoSCC). Bibliometrix was used for science mapping of the literature, while VOSviewer and CiteSpace were applied to visualize co-authorship, co-citation, co-occurrence, and bibliographic coupling networks.ResultsWe identified four major research trends: (1) pathophysiological mechanisms; (2) treatment strategies; (3) cardiac fibrosis and related CVDs; (4) early diagnostic methods. The most recent and important research themes such as left ventricular dysfunction, transgenic mice, and matrix metalloproteinase were generated by burst analysis of keywords. The reference with the most citations was a contemporary review summarizing the role of cardiac fibroblasts and fibrogenic molecules in promoting fibrogenesis following myocardial injury. The top 3 most influential countries were the United States, China, and Germany, while the most cited institution was Shanghai Jiao Tong University, followed by Nanjing Medical University and Capital Medical University.ConclusionsThe number and impact of global publications on cardiac fibrosis has expanded rapidly over the past 30 years. These results are in favor of paving the way for future research on the pathogenesis, diagnosis, and treatment of cardiac fibrosis.
Farmers’ social networks’ effects on the sustainable production of fresh apples in China’s Shaanxi province
Authors: Khan Zaid Ashiq , Zhu Jialin , Khan Aftab , Koondhar Mansoor Ahmed , Kakar Shayan Khan , Ali Uzair , Tianjun Liu 
Published: June 2023

Introduction: Recently, the public and policymakers have acquired knowledge of the detrimental effects of pesticide use in agriculture. These include the threat to the health of chemical applicators and the threat that pesticide residues pose to the safety of food. The present study focuses on the farmers’ social networks from a new perspective, along with the farmers’ concurrent agricultural business and their impact on the farmer’s safe production behavior.Methodology: The Endogenous Switching Probit Regression model and Binary Probit Group Regression model were employed for the empirical analysis of survey data collected from 585 households in the Xianyang, Yan’an, and Weinan districts of Shaanxi province, China.Results and Discussion: The results revealed that farmers’ social networks can greatly affect farmers’ safe production behavior. Additionally, we noted that the farmers’ social networks may play a positive role in promoting the farmers’ safe production behaviors of both concurrent agricultural business and non-concurrent agricultural business farmers. Moreover, their correlation coefficients were found significant at a confidence level of 5%. Our findings suggest that the government needs to construct social networks among farmers by setting up a communication platform and promoting the acquaintance of safe production through reciprocal culture.