bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical Profile, Laboratory Findings and Outcome of Severe Dengue Infection among Children Admitted at a Tertiary Care Hospital in Bangladesh
Authors: Ferdous Jannatul , Hassan M Quamrul , Sultana Sabina , Naher Nurun , Hossain Mohammed Istiaque , Nessa Badrun , Nahar Laila Nurun , Nahid Farzana 
Published: August 2023

Background: Dengue infection is endemic in Bangladesh and presents with varying degrees of severity of illness in children.
Objective: The purpose of the present study was to assess the common clinical profile, biochemical findings and outcome of severe dengue fever in children.
Methodology: This prospective cohot study was conducted on dengue NS1 or IgM or RT-PCR positive admitted children up to 14 years of age from April 2019 to October 2019 for a period of 6 months at the Pediatrics Department of Evercare Hospital, Dhaka. Data were analyzed after collection of demographic variables, presenting complaints and examination findings of 75 enrolled children.
Results: A total of 75 cases were classified as severe dengue fever. The most common age of presentation was 4 to 7 years. The most common presenting symptom of severe dengue cases were fever (97.3%), abdominal pain and vomiting (77.3%) and shock (62.7%). Pleural effusion was the most common physical findings seen in 35 cases (46.6%) followed by ascites in 26 cases (34.7%). Elevation in aspartate amino transaminase AST (IU/L) was found in 82.6%, low albumin was found in 78.7% of the cases. Hypernatremia was the most common electrolyte abnormality found in 35 cases (46.7%). Regarding coagulation profile, raised D-dimer & low fibrinogen were found in 53 (70.7%) & 42 cases (56.0%) respectively. Activated partial thromboplastin time (aPTT) was prolonged in 37.3%. Case fatality rate (CFR) was 5.3%.
Conclusion: In conclusion, raised AST and D-dimer, low fibrinogen & albumin level as well as hyponatremia are significant laboratory findings indicating severity of the disease. Shock is a common presentation of severe dengue in children.
Bangladesh Journal of Infectious Diseases, December 2022;9(2):40-46
ALIGNMENT POROS POMPA BENFIELD 1107-JB MENGGUNAKAN DIAL INDIKATOR DENGAN METODE RIM AND FACE
Authors: Bastiar Afif Chaniago , Witanto Yovan , Suryadi Dedi 
Published: August 2023

Alignment adalah suatu proses yang mensejajarkan dua sumbu poros yang tidak lurus hingga sentris (antara poros penggerak dengan sumbu poros yang digerakkan). Alignment yang benar diperlukan agar pengecekan run out pada kopling benar, sehingga tidak terjadi lagi parallel misalignment dan angular misalignment yang mengakibatkan industry kehilangan miliar dolar. Tujuan dari penilitian ini adalah untuk menganalisis ferforma aligment pada poros pompa benfield 1107 JB PT. PUSRI untuk menciptakan aligment yang benar. Metode yang digunakan dalam penelitian ini adalah dial indikator dengan metode face and rim. Alat ukur yang digunakan adalah Dial Indikator dengan detail ketelitiannya sebesar 0.01 mm dengan pengukuran radial dan axial. Hasilnya menunjukkan nilai akhir yang berbeda untuk setiap sudut yang digunakan. Dari selisi nilai yang didapat yaitu pada arah radial sudut 0o yaitu 0 mm, sudut 90o sebesar 0,07 mm, sudut 180o sebesar 0,14 mm, dan sudut 270o sebesar 0,07 mm, dan selisih nilai pada arah axial sudut 0o sebesar 0 mm, sudut 90o sebesar 0,01mm, sudut 180o sebesar 0,01 mm, serta sudut 270o sebesar 0 mm menunjukkan bahwa Pompa benfield 1107-JB siap untuk operasikan kembali pada P-IV bagian Amonia.
Time-intensity profile and relationship with consumer acceptability of processed cheese spread
Authors: Palazzo Alessandra Bugatte , Biasoto Aline Camarão Telles , Dionísio Ana Paula , Cadena Rafael Silva , Bolini Helena Maria André 
Published: August 2023

Creamy “requeijão” is the commercially most prominent processed cheese spread in Brazil. The time intensity analysis is important to provide how the flavor behavior is for the consumers during the food ingestion and is used in order to obtain the temporal profile of an attribute in a certain product. In the present study, three different commercial brands, leaders in the market, in their traditional and light versions, were subjected to sensory and instrumental evaluations. Time-intensity analyses and acceptance tests were carried out. After the statistical evaluation, applying ANOVA, the Tukey test (p. 0.05), Partial Least Square (PLS), it was concluded that the consumers preferred products with a more intense cheese flavor and higher adhesiveness, besides expressing a greater acceptance and purchase intention for the product in its traditional version.
Avaliação das características fitoquímicas e das toxicológicas dos frutos da Averrhoa carambola L: uma revisão integrativa da literatura
Authors: Alcântara Elvis Robertson da Silva , Santos Sônia Irene Carvalho dos , Gonçalves Karine de Sousa , Delgado Jéssica Proência dos Santos , Rivera Juan Gonzalo Bardalez , Santos Gabriel Cardoso de Queiroz , Quemel Gleicy Kelly China 
Published: August 2023

A Averrhoa carambola L. é amplamente distribuída e cultivada em países de clima tropical. Acredita-se que o fruto possui intensa atividade metabólica secundária podendo apresentar múltiplas bioatividades, como: anti-hiperglicêmico, antiobesidade, anti-hiperlipidêmico, hepatoprotetor, cardioprotetor, anti-hipertensivo e neuroprotetores. Dessa forma, o trabalho teve como objetivo analisar, por meio da literatura, o perfil fitoquímico e o toxicológico dos frutos da Averrhoa carambola L. Trata-se de uma revisão integrativa sendo incluídas todas as literaturas completas, nas línguas inglesa e portuguesa, no período de 2012 a 2021. Foram excluídos guidelines, pre prints, artigos pagos e duplicatas. A literaturas que compuseram a revisão são das bases de dados SciELO, MEDLINE e LILAC de repositórios de nível superior. Foram elegíveis 10 literaturas para essa revisão, sendo – 70% (7) na SciELO; 20% (2) MEDLINE e 10% (1) na LILACS, os quais 50% (5) estão no idioma inglês e 50% (5) em português. A A. carambola L pode atuar como inibidor ou potencializa dor enzimático e interferir em processos relacionados ao equilíbrio hemostático: coagulação; dissolução de trombos e a fibrinogenólise; apresenta flavonóides e taninos e o seu uso popular pode realmente trazer benefícios à saúde da população, porém pode apresentar efeito nefrotóxico e neurotóxico, para pacientes renais crônicos.
CLASSIFICATION OF CORN PLANT DISEASES USING VARIOUS CONVOLUTIONAL NEURAL NETWORK
Authors: Pratama Aditya Yoga , Pristyanto Yoga 
Published: August 2023

Based on data from the East Java Badan Pusat Statistik (BPS) in 2020, corn production in 2019 decreased by 622,403 tons. The decrease in production was caused by a disease that attacked corn plants identified from the corn leaves' physical appearance. This study aims to obtain an architectural model with good performance between AlexNet, LeNet, and MobileNet in detecting diseases of maize plants. The dataset used in this study came from Kaggle, with 4188 images divided into four disease classes: Common Rust, Gray Leaf Spot, Blight, and Healthy. Agricultural experts from Bantul have confirmed the appearance of each class of corn plant diseases. The preprocessing process is carried out to prepare the data so that the amount of data for each class is balanced. The image data used in this study totaled 4000 images which were divided into training data and testing data with a ratio of 80:20. Based on the experimental results, it was found that the MobileNet architecture has better performance than AlexNet and LeNet with an accuracy value of 83.37%, average precision of 0.8337, and g-mean of 0.8298. These results have been validated by agricultural experts in Bantul Regency and corn farmers experienced in corn farming.
THE FUNCTION OF SOCIAL MEDIA AS A SUPPORTING TOOL FOR LECTURER CAREER DEVELOPMENT IN UNIVERSITIES IN THE INDUSTRY 4.0 ERA
Authors: Ibrahim Ali , Heroza Rahmat Izwan , Reza Iredho Fani , Afrina Mira , Utama Yadi 
Published: August 2023

Lectures have many duties. The most important one is to implement the tri-dharma of higher education (teaching, research and community service). One of the efforts to support these duties in the Industry 4.0 era is the use of social media to develop professors' careers. A lack of understanding of the role of social media sometimes only sees the dark side of social media, which is actually very useful in developing lecturers' careers. This study uses a qualitative research method with a narrative research design. The subjects of this study were 92 individuals identified through purposive sampling technique. Data collection was done through an online survey. Data analysis in this study used coding techniques consisting of open coding, axial coding and selective coding stages. The findings of this study show that social media is a professional development tool for teachers and can enhance professional competence, which can contribute to teachers' professional development. Professional development that enhances the performance of the Tri Dharma of Higher Education in the areas of teaching, research and community service.
EFFORTS TO INCREASE STUDENTS’ LEARNING OUTCOMES THROUGH PROBLEM BASED LEARNING MODEL ON THE MATERIAL OF THE EFFECTS OF HEAT ON CHANGES IN THE FORM OF OBJECTS IN CLASS V AT SDN 112 PALEMBANG
Authors: Latifah Anisa Resti , Indralin Vinencia Ika , Maharani Siti Dewi 
Published: August 2023

This research is a class action research (CAR) conducted in class V SDN 112 Palembang. This research was conducted in class V A with a total of 25 students consisting of 12 boys and 13 girls. This study aims to improve the learning outcomes of students on the science content of the material of the effect of heat on changes in the forn of objects by using the problem based learning model in class V A SDN 112 Palembang. Data collection techniques in this research used test and nontest. I the form of observation and documentation. Pre-cycle results with KKM 70, the acquisition of scores obtained by students is still a lot below KKM, <70 there are 21 students and there are 4 completed students. Based on the results of this research, the action on cycle 1 using the model problem based learning has reached the KKM score of 64% of all student with an average of 70.8. Aplication of cycle 2 increased to 96% with an average of 90.8. This suggest that the application of the problem based learning model in the science content of the material of the effect of calor on changes in the form of objects in the class V A at SDN 112 Palembang can improve the learning outcomes.
TOTAL ASET, SISTEM PENGENDALIAN INTERNAL, LEVERAGE, ROA DAN AUDIT DELAY PADA PERUSAHAAN GO PUBLIC
Authors: Ardi Bagus Kusuma , Sutopo Sutopo , Harjanto Sri 
Published: August 2023

Tema penelitian ini adalah Audit Delay, bertujuan menganalisis pengaruh total aset, sistem pengendalian intern, leverage dan return on asset terhadap audit delay pada perusahaan yang terdaftar di Bursa Efek Indonesia pada tahun 2020. Populasi meliputi semua perusahaan go public yang terdaftar di BEI, berjumlah 786 perusahaan dan diambil sebagai sampel sebanyak 87 perusahaan yang dipilih secara random. Analisis menggunakan metode regresi linier berganda, yang hasilnya menunjukkan total aset tidak berpengaruh signifikan terhadap audit delay, leverage berpengaruh positif signifikan terhadap audit delay, sedangkan system pengendalian intern dan return on asset berpengaruh negatif signifikan terhadap audit delay.
Cerebral autoregulation and cerebral blood flow response to mean arterial pressure challenge following induction of general anaesthesia for neuroradiology procedure
Authors: Manquat Elsa , Ravaux Hugues , Souilamas Jihane , Chamoux Thibaut , Joaquim Jona , Gayat Etienne , Vallée Fabrice , Cartailler Jérôme 
Published: August 2023

IntroductionIntraoperative hypotension is common following general anaesthesia induction with propofol, but its impact on cerebral autoregulation (CA) remains unclear. We investigate the incidence and risk factors of impaired CApost-propofol induction and its recovery after a mean arterial pressure (mAP) challenge.MethodsWe included 40 non-emergency neuroradiology surgery patients [58 (47, 58)years old., 57% women]. We recorded mAP, mean blood flow velocity in the mean cerebral artery (MCAvmean), and regional cerebral oxygen saturation (rSO2). We computed the mean flow index (Mxa) pre and post mAP challenge. Mxa &gt; 0.3 defined poor CA.ResultsAfter anaesthesia induction, 21 (53%) had impaired CBF autoregulation (CA−, Mxa &gt; 0.3). The average mAP was 66 ± 9 mmHg, average MCAv was 39 ± 12 cm.s−1, and rSO2 was 63 ± 7%. We found no significant difference in age, norepinephrine infusion rate, and cardiovascular risks factors were similar between CA− and CA+ (Mxa ≤ 0.3) patients. Among the 22 patients (CA−: n = 14; CA+: n = 8) undergoing mAP challenge, there was a significant Mxa improvement and MCAv increase among CA− patients, (CA−: 0.63 ± 0.18 vs. 0.28 ± 0.20, p &lt; 0.001), and [absolute variation: 1 (0.7–1.5) vs. 7 (3–9) cm.sec−1], respectively.ConclusionAfter induction of general anaesthesia for neuroradiology procedure, 53% of the patients had an impaired CA, regardless of age or medical history. Importantly, a mAP challenge effectively restored CA and improved CBF.Clinical Trial Registrationidentifier, NCT04288869
Effects of citrate-stabilized gold and silver nanoparticles on some safety parameters of Porphyridium cruentum biomass
Authors: Rudi Ludmila , Cepoi Liliana , Chiriac Tatiana , Miscu Vera , Valuta Ana , Djur Svetlana 
Published: August 2023

Introduction: Our research raises the question of how realistic and safe it is to use gold and silver nanoparticles in biotechnologies to grow microalgae, which will later be used to obtain valuable products. To this purpose, it was necessary to assess the influence of 10 and 20 nm Au and Ag nanoparticles stabilized in citrate on the growth of microalga Porphyridium cruentum in a closed cultivation system, as well as some safety parameters of biomass quality obtained under experimental conditions.Methods: Two types of experiments were conducted with the addition of nanoparticles on the first day and the fifth day of the cultivation cycle. Changes in productivity, lipid content, malondialdehyde (MDA), as well as antioxidant activity of microalgae biomass have been monitored in dynamics during the life cycle in a closed culture system.Results: The impact of nanoparticles on the growth curve of microalgae culture was marked by delaying the onset of the exponential growth phase. A significant increase in the content of lipids and MDA in biomass was noted. Excessive accumulation of lipid oxidation products within the first 24 h of cultivation resulted in altered antioxidant activity of red algae extracts.Discussion: Citrate-stabilized gold and silver nanoparticles proved to be a stress factor for red microalga Porphyridium cruentum, causing significant changes in both biotechnological and biomass safety parameters. Addition of Au and Ag nanoparticles during the exponential growth phase of porphyridium culture led to an enhanced lipid accumulation and reduced MDA values in biomass.
Senescence during early differentiation reduced the chondrogenic differentiation capacity of mesenchymal progenitor cells
Authors: Voskamp Chantal , Koevoet Wendy J. L. M. , Van Osch Gerjo J. V. M. , Narcisi Roberto 
Published: August 2023

Introduction: Mesenchymal stromal/progenitor cells (MSCs) are promising for cartilage cell-based therapies due to their chondrogenic differentiation capacity. However, MSCs can become senescent during in vitro expansion, a state characterized by stable cell cycle arrest, metabolic alterations, and substantial changes in the gene expression and secretory profile of the cell. In this study, we aimed to investigate how senescence and the senescence-associated secretory phenotype (SASP) affect chondrogenic differentiation of MSCs.Methods: To study the effect of senescence, we exposed MSCs to gamma irradiation during expansion or during chondrogenic differentiation (the pellet culture). Western blot analysis was used to evaluate MSCs response to the chondrogenic inductor TGF-β.Results: When senescence was induced during expansion or at day 7 of chondrogenic differentiation, we observed a significant reduction in the cartilage matrix. Interestingly, when senescence was induced at day 14 of differentiation, chondrogenesis was not significantly altered. Moreover, exposing chondrogenic pellets to the medium conditioned by senescent pellets had no significant effect on the expression of anabolic or catabolic cartilage markers, suggesting a neglectable paracrine effect of senescence on cartilage generation in our model. Finally, we show that senescent MSCs showed lower phosphorylated SMAD2 levels after TGFβ1 stimulation than control MSCs.Conclusion: Overall, these results suggest that the occurrence of senescence in MSCs during expansion or early differentiation could be detrimental for cartilage tissue engineering.
Observational study of endoluminal mural thrombotic apposition in popliteal artery aneurysm stenting and its relationship with stent-graft geometrical features
Authors: Spinella Giovanni , Conti Michele , Magliocco Marco , Pisa Fabio Riccardo , Finotello Alice , Pulze Martina , Pratesi Giovanni , Cittadini Giuseppe , Salsano Giancarlo , Pane Bianca 
Published: August 2023

IntroductionThe development of intrastent thrombosis is one of the mechanisms related to medium- to long-term failure of endovascular treatment of popliteal artery aneurysm. The present study aims to investigate possible links between the development of endoluminal mural thrombotic apposition in the stented zone (EMTS) with both geometrical features of stent-graft(s) and time of follow-up.MethodsPatients with popliteal artery aneurysm who underwent endovascular treatment were recruited during the follow-up period. Segmentation of computed tomography angiography scan was performed to detect femoropopliteal artery lumen, leg bones, EMTS, and stent-graft(s). The following parameters were assessed: number, diameter, and length of stent-graft(s); and shape, volume, and length of thrombotic apposition within the stent(s). The spiral shape of the thrombotic apposition was evaluated as well.ResultsEighteen male patients were recruited in the study. EMTS was observed in 13 of them (72%) during the follow-up analysis. An average of 1.8 ± 0.79 stents-grafts were implanted per patient with a median diameter and length of 6.2 (1.9) mm and 125 (50) mm, respectively. The percentage of the stent length where EMTS was present was 42.1 on average (interquartile range: 42.4%) with a mean volume of 206.8 mm3. A positive correlation was found between the length and volume of EMTS (R-squared = 0.71, p &lt; 0.01). Moreover, EMTS had a helical shape in 8/13 patients, with 4/5 with counterclockwise rotation with stent-grafts in the left leg and 3/3 with clockwise direction treated in the right leg. A higher frequency of EMTS was observed in patients with longer follow-up and higher risk factors, as well.ConclusionsEMTS is observed in most of the patients under analysis, especially in those with medium- to long-term follow-up. The pattern of such EMTS follows a helical shape having a direction that depends on which leg, right or left, is treated. Our results suggest a close surveillance of popliteal aneurysm stenting by follow-up examinations to control the onset and progression of EMTS.
Strategies and outcomes of different methods for treating abdominal aortic stent graft infection
Authors: Zhang Mengqiang , Chen Zhipeng , Tang Chen , Liu Cheng , Li Xiaoqiang , Liu Zhao , Qiao Tong 
Published: August 2023

ObjectiveTo report the strategies and short-term results of different treatment methods for abdominal aortic stent graft infection.MethodsSix consecutive patients (5 males and 1 female; mean age: 64 years; age range: 49–79 years) received surgical treatment for stent graft infection from November 2021 to December 2022. All patients underwent endovascular aortic repair (EVAR) for abdominal aortic and iliac artery disease, subsequently developed graft infection and then received corresponding surgical treatment with different materials (artificial blood vessel, bovine pericardium, autologous great saphenous vein) in our department. The outcomes were analysed.ResultsImmediate technical success was achieved intraoperatively in all six patients. The 30-day mortality rate was 0%. During a mean follow-up of 4 months (range, 3–13 months), one patient underwent a second operation due to vascular anastomotic haemorrhage and underwent bilateral limb amputations due to ischaemia. All patients survived.ConclusionsIn the short term, the different materils and methods used to treat aortic stent graft infection achieved satisfactory results.
Procedural success of transcatheter annuloplasty in ventricular and atrial functional tricuspid regurgitation
Authors: Barbieri Fabian , Mattig Isabel , Beyhoff Niklas , Thevathasan Tharusan , Romero Dorta Elena , Skurk Carsten , Stangl Karl , Landmesser Ulf , Kasner Mario , Dreger Henryk , Reinthaler Markus 
Published: August 2023

BackgroundTranscatheter annuloplasty is meant to target annular dilatation and is therefore mainly applied in functional tricuspid regurgitation (TR). Due to recent recognition of varying disease pathophysiology and differentiation of ventricular and atrial functional TR (VFTR and AFTR), comparative data regarding procedural success for both disease entities are required.MethodsIn this consecutively enrolled observational cohort study, 65 patients undergoing transcatheter annuloplasty with a Cardioband® device were divided into VFTR (n = 35, 53.8%) and AFTR (n = 30, 46.2%). Procedural success was assessed by comparing changes in annulus dilatation, vena contracta (VC) width, effective regurgitation orifice area (EROA), as well as reduction in TR severity.ResultsOverall, improvement of TR by at least two grades was achieved in 59 patients (90.8%), and improvement of TR by at least three grades was realised in 32 patients (49.2%). Residual TR of ≤2 was observed in 52 patients (80.0%). No significant differences in annulus diameter reduction [VFTR: 11 mm (9–13) vs. AFTR: 12 mm (9–16), p = 0.210], VC reduction [12 mm (8–14) vs. 12 mm (7–14), p = 0.868], and EROA reduction [0.62 cm2 (0.45–1.10) vs. 0.54 cm2 (0.40–0.70), p = 0.204] were reported. Improvement by at least two grades [27 (90.0%) vs. 32 (91.4%), p = 1.0] and three grades [14 (46.7%) vs. 18 (51.4%), p = 0.805] was similar in VFTR and AFTR, respectively. No significant difference in the accomplishment of TR grade of ≤2 [21 (70.0%) vs. 31 (88.6%), p = 0.118] was noted.ConclusionAccording to our results from a real-world scenario, transcatheter annuloplasty with the Cardioband® device may be applied in both VFTR and AFTR with evidence of significant procedural TR reduction.