bluuebunny/crossref_metadata_2025_split huggingface dataset:
The role of salivary orosomucoid 1 as an early diagnostic and prognostic biomarker of hepatocellular carcinoma related to Hepatitis B: A systematic review
Authors: Limijadi Edward Kurnia Setiawan , Ar Ardiyana , Rahmawati Nurul Azizah Dian , Sudiasa I Nyoman Sebastian , Tjandra Kevin Christian 
Published: June 2023

Background: Salivary orosomucoid 1 (ORM1) is highly increased in hepatocellular carcinoma related to hepatitis B. Thus, this systematic review aimed to investigate the diagnostic and prognostic value of salivary orosomucoid 1 (ORM1) in patients with that mentioned disease. Methods: The sources included were original articles published from 2013 until 2023 (last date searched, January 2023) from 4 databases (ProQuest, Google Scholar, Springer, and ScienceDirect). The inclusion criteria were original research articles (observational cohort or diagnostic studies). Other article reviews, meta-analyses, non-comparative research, and in silico, in vitro and in vivo studies, technical reports, editor responses, conference abstracts, non-English, non-full-text, and irrelevant articles that were not related to either salivary ORM1, or hepatocellular carcinoma, hepatitis B, or kidney failure were excluded. Then, the ROBINS-I taken was used to assess bias. The result was constructed with PICOS criteria within the table created in the Google spreadsheet. This systematic review followed the PRISMA guidelines. Results: Five diagnostic studies with 533 samples conducted in China and Japan. Limited original studies with homogenous PICO were a limitation, but the evidence output of this study can still be well presented. Salivary ORM1 may be useful to detect early cancer diagnosis as rapidly increased levels of ORM1 can be observed in the early stages of HCC (four times higher than usual) and the biomarker has a sensitivity of 81.67% and a specificity of 77.5%. This biomarker can detect the prognosis of individuals with the disease with or without chemotherapy. It is because level of salivary ORM1 related to liver damage, the higher the level of ORM1, the more liver damage occurs which leads to a poorer prognosis. Conclusions: Salivary ORM1 is a potential early diagnostic biomarker of HCC related to hepatitis B and a biomarker of the disease prognosis. Registration: Open Science Framework (OSF) (March 16, 2023).
Mapping the international ecosystem of national health data spaces. A scoping review protocol
Authors: Maxwell Lauren 
Published: June 2023

Background: The reuse of participant-level health data by public health and surveillance institutions, hospitals, doctors, and patients is an emerging priority for a number of national governments. Technical and semantic interoperability of health data ecosystems is important for detecting and responding to global health challenges, including emerging infectious diseases, antimicrobial resistance, and vaccine-preventable illnesses. In this scoping review, we will identify and describe health data ecosystems, spaces, clouds, and commons, national-level mechanisms for enabling the reuse of participant-level health data. Methods and analysis: We will apply the Arskey and O’Malley scoping review approach to describe governance, content, and semantic and technical interoperability of data and metadata in national health data ecosystems. We selected a scoping rather than a systematic review methodology to provide a high-level analysis of the current state of health data ecosystems’ implementation of the FAIR principles for data resources. The systematic search strategy was pilot tested and tailored for Ovid(Medline), CINAHL, and Web of Science. We will also conduct web scraping and consult stakeholders to identify additional health data ecosystems. Two reviewers will conduct the title-abstract and full-text screening and data charting independently. Discrepancies will be resolved by consensus, and results will be summarized in narrative form. Ethics and dissemination: Ethical approval is not required for this scoping review of published studies and grey literature. The scoping review protocol was registered prior to initiating the search strategy. Study results will be submitted for publication in an Open Access journal.
Testing The Relationship Between Trust And Positive Relationships Within A Top Management Team: A Second-Order Structural Equation Modeling Approach
Authors: Jozefowicz Barbara , Fu Yusheng , Martin-Rojas Rodrigo 
Published: June 2023

Purpose: This paper presents the results of investigation of how trust within the team affects positive interpersonal relationships in top management teams (TMT).
Design/Methodology/Approach: In accordance with the positive approach in management sciences positive relationships and trust within teams are crucial resources which allow management teams to face the strategic challenges of the modern market. Based on critical literature review the theoretical framework of the model was created to test the relationship between antecedents of trust and positive interpersonal relationships within TMTs. The study is based on a survey conducted on a sample of 123 top managers and members of teams in Poland. The verification of the theoretical model was performed based on a second-order structural equation modelling approach.
Findings: This research shows that among antecedents of trust
Originality/value: Studies of managerial teams in the field of interpersonal relations are rare. This paper contributes to fill this gap by selecting TMT teams as subjects for research. The study reported in this paper contributes to current understanding of the nature of relationship between trust and positive relationships in team.
Keywords: trust, positive relationships, top management team (TMT), trust within team
Paper type: Research paper.
UV generation via periodically poled MgO:LiTaO3circular waveguide crystal and diode-based master oscillator power amplifier
Authors: Mourikis Christos , Werner Nils , Feise David , Paschke Katrin , Tränkle Günther 
Published: June 2023

Lasers with emission wavelengths in the near-ultraviolet (UV) spectral range have been used in many applications across various fields, and the demand for these lasers has been on the rise. For example, in medicine, near-UV light has been used for fluorophore excitation. Although laser diodes emitting in this region exist, single longitudinal mode lasers emitting at 380 nm with high optical power are limited. One of the solutions to this problem is the use of second harmonic generation by a non-linear crystal. In this work, single-longitudinal-mode laser emission at 380.5 nm with an optical power of up to 13 mW has been achieved. The emission was realized by frequency doubling using a periodically poled circular waveguide crystal of stoichiometric LiTaO3doped with MgO (PPMgSLT) pumped by a master oscillator power amplifier with optical power up to 5 W. A distributed Bragg reflector ridge waveguide laser diode at 761 nm was used as the master oscillator and a tapered amplifier as the power amplifier.
Analisis Risiko Kesehatan Karyawan Terhadap Pajanan Kadmium (Cd) dan Eschericia coli di Industri
Authors: Mulyati Sri Slamet , Maulani Fenni , Aristawati Farah Ayu , Iqbal Muhamad , Irianto Redi Yudha 
Published: June 2023

Latar Belakang: Karyawan berhak mendapatkan pelayanan yang menjamin kesehatan dan keselamatannya ketika mereka bekerja. Ketika menggunakan air bersih untuk higiene dan sanitasinya, pastikan air tersebut tidak berdampak secara lagsung maupun tidak langsung terhadap kesehatannya. Risiko kesehatan terhadap karyawan apabila mengkonsumsi air tersebut bisa diprediksi melalui analisis risiko kesehatan lingkungan. Tujuan: Mengetahui risiko non karsinogenik dan mikroba akibat pajanan Kadmium (Cd) dan E. coli dalam air bersih.Metode: Penelitian ini adalah deskriptif dengan pendekatan analisis risiko kesehatan lingkungan. Sampel manusia adalah orang dewasa dengan menggunakan nilai default berat badan orang dewasa 55 Kg. Sampel lingkungan adalah air bersih di industri tekstil PT.X Kota Cimahi.Hasil: Intake Kadmium (Cd) belum menunjukkan adanya bukti kanker dalam pajanan oral sehingga tidak dihitung dalam studi ini. Pajanan Cd dalam air bersih secara oral belum berisiko non karsinogenik (RQ = 0,20756). Peluang terinfeksi akibat pajanan E.coli dalam air bersih ( P = 4,34 x 10-5), dan peluang sakit (P = 1,572 x 10-2).Simpulan: Keberadaan Cd dalam air bersih belum berisiko non karsinogenik (RQ < 1). Keberadaan E. coli dalam air bersih berpeluang menginfeksi > 1 per 100.000 karyawan, dan berpeluang menimbulkan sakit > 1 per 100 karyawan industri PT.X Kota Cimahi dalam setahun. ABSTRACT:Title: Employee Health Risk Analysis of Cadmium (Cd) and Eschericia coli Exposure in IndustryBackground: Employees have the right to get services that ensure their health and safety when they work. When using clean water for hygiene and sanitation, ensure that the water does not directly or indirectly impact on their health. The health risks to workers if they consume water can be predicted through an environmental health risk analysis. Objective: Knowing the carcinogenic, non-carcinogenic, and microbial risks due to exposure to Cadmium and E.coli in clean water. Methods: This research was descriptive with environmental health risk analysis approach. Human samples were adults using the default value of the adult weight of 55 Kg. Environmental samples were clean water in the textile industry PT.X Cimahi City. Result: Exposure to Cd in clean water orally did not pose a carcinogenic risk. Exposure to Cd in clean water orally had a non-carcinogenic risk (RQ = 0.20756). The probability of becoming infected due to exposure to E.coli in clean water (P = 4.34 x 10-5), and the probability of illness (P = 1.572 x 10-2) Conclusion: The presence of Cd in clean water had no non-carcinogenic risk (RQ < 1). The presence of E.coli in clean water had the opportunity to infect > 1 per 100,000 employees, and has the opportunity to cause illness > 1 per 100 industrial employees of PT. X Cimahi City in a year.
Changes in Tolaki People Burial in Southeast Sulawesi: From Boat-Shaped Grave Coffin (Soronga) to Boat-Shaped Islamic Tomb (Koburu Bangga)
Authors: Syahrun Syahrun , Melamba Basrin 
Published: June 2023

The first burial system of Tolaki people in prehistoric times and ancient times adopted boat-shaped grave coffin known as soronga or oduni. There were large and small soronga and there were also decorated and undecorated or plain soronga. When Islam was introduced in the Mekongga Kingdom during the leadership of King/Bokeo Laduma in 17th century and in Konawe in 18th century, the burial system was adopted. However, the tradition of using boats experienced a change. During the Islamic era, there were two shapes of grave in the Islamic grave called as ninggeo-nggeo where the grave was placed in a hole made on the side of the excavation and tinandapa where the grave was placed in a hole made in the middle of the excavation and it was intended for elite and influential ruler. There were also four models of tomb types, namely circle (buboto/loelole), rectangular (konahuu), rectangular step pyramid, elongated (menda’a), and boat-shaped (obangga). koburu bangga tomb. The distribution pattern of the tombs varied, there were converging (metobu), circular, and spreading patterns. The shape of tombstone also varied, it resembled pappilus genital, round stone, wide wood and stone, human head, knights grinding stone (oliro). It was made of stone, river stone, mountain stone, wood, and even tree was also used as a tomb marker. The boat-typed tomb still maintained because a faith that the deceased need vehicles to go to their destination. It is also affected by maritime world at the past as well as technology that lived in the past used by a collective memory.
Timor Zone: Slave Trading Network from the Traditional Era to the Late Nineteenth-Century Dutch Colonial State
Authors: Sholihah Fanada , Rochwulaningsih Yety , Sulistiyono Singgih Tri 
Published: June 2023

This article examines the continuity and changes of the Timorese slave trade network from the traditional era to the late nineteenth-century Dutch colonial state. Archival records, newspapers, and other literature were used extensively to reconstruct the map of the Timorese slave trading. Grasping the dynamics of change and trade networks of Timor, there were two proposed research questions: First, how did the Timorese slave trading network experience continuity and change from the traditional period until the late nineteenth-century Dutch colonial state? Second, to what extent does the need for labour in the global and Southeast Asian context play in shaping and catalyzing the expansion of the Timorese slave network? Timor and its surroundings were deemed slave enclaves (peripheries) with several trading centres. Traditionally, slave trade routes formed from Timor to Java and Malacca. In addition, it was intended for Dili and Macau during the Portuguese era. During the VOC era, Batavia and Banda were the busiest routes of the Timorese slave trade. Networking was increasingly across-the-board, along with the need for labour to meet the demands of the global market. Henceforward, during the Dutch East Indies, the slave trading network continued expanding to Maurits, Réunion, Macau, Mozambique, and Mombasa and several years after the post-prohibition of slavery, leaving Ende Bay as the only centre of the slavery trade.
A pattern catalog for augmenting Digital Twin models with behavior
Authors: Lehner Daniel , Sint Sabine , Eisenberg Martin , Wimmer Manuel 
Published: June 2023

Abstract
Digital Twins are emerging as a solution to build and extend existing software systems to make better use of data produced by physical systems. For supporting the development of Digital Twins, several software vendors are offering dedicated tool support, often referred to as Digital Twin platforms. The modeling capabilities of these platforms are mostly concerned with structural viewpoints, i.e., providing an overview of available components including their current and historical sensor values. However, behavioral viewpoints did not yet receive much attention on these platforms. As behavioral models are often used during the design processes, e.g., for simulation and synthesis, it would be beneficial for having them included in Digital Twin platforms, e.g., for reasoning on the set of possible next actions or for checking the execution history to perform runtime validation. In this paper, we present a catalog of modeling patterns for augmenting Digital Twin models with behavioral models and their corresponding runtime information without requiring any extension of the code bases of Digital Twin platforms. We demonstrate the presented modeling patterns by applying them to the Digital Twin platform offered by Microsoft, in an additive manufacturing use case of a 3D printer in a production line.
Bad Smells in Steuerungssoftware für automatisierte Produktionssysteme
Authors: Sonnleithner Lisa , Gutiérrez Antonio , Rabiser Rick , Zoitl Alois 
Published: June 2023

ZusammenfassungBad Smells sind suboptimale Strukturen oder Muster in Software, die zu einer Verschlechterung der Softwarequalität führen können, da sie unter anderem Wartungsprobleme verursachen und die Verständlichkeit erschweren können. Um das Auftreten dieser Probleme zu vermeiden, ist es deshalb wichtig, Bad Smells in Software erkennen und beheben zu können. Im Software Engineering ist das Thema Bad Smells bereits gut erforscht. Für IEC 61499-basierte Steuerungsoftware, die in automatisierten Produktionssystemen verwendet wird, gibt es jedoch erst wenige Arbeiten zu diesem wichtigen Thema.
Cyberangriffe blockierende programmierbare Automatisierungssysteme
Authors: Halang Wolfgang A. 
Published: June 2023

Zusammenfassung
Fast täglich wird über Hackerangriffe und Datenspionage berichtet – Phänomene, die auch die funktionale Sicherheit rechnergestützter Automatisierungssysteme gefährden. Darüber würden die Erfinder der Digitalrechner, Charles Babbage und Konrad Zuse, nur gelacht haben; denn es war unmöglich, ihre Maschinen von außerhalb zu beeinflussen, und zwar auch dann, wenn sie über Telekommunikationseinrichtungen verfügt hätten. Auch heute könnte mit marktüblicher Technologie das Auftreten aller Sicherheitsprobleme der digitalen Informations- und Kommunikationstechnik in einfacher Weise konstruktiv verhindert werden, d.h. Rechner lassen sich bauen, an denen alle denkbaren Hackerangriffe konstruktionsbedingt abprallen. Weiterhin wird an eine vor über 100 Jahren patentierte Datenverschlüsselungsmethode erinnert, deren Wirkprinzip systematisches Entschlüsseln und Überflutungsangriffe unmöglich macht.
Lang lebe der König! Aber auch der optative Konjunktiv?!
Authors: Scholübbers Laura 
Published: June 2023

Abstract
The now archaic optative subjunctive was common in earlier forms of the German language. This paper examines two questions: Why is the optative subjunctive rarely used today? Which linguistic constructions are presently used in the contexts and functions that originally accompanied the optative subjunctive? The paper goes beyond previous studies on this subjunctive and its substitutes by explaining closely how its context, function and syntax in historical instances may have an impact on the constructions that have replaced it. Furthermore, this paper argues that pragmatic change, economy, analogy and especially expressiveness can explain such displacement by specific constructions.
„We Are Made of Star-Stuff“
Authors: Gregor Joris A. , Rosa Hartmut 
Published: June 2023

Abstract
Connectedness is a significant element of sociality that occurs not only ideally and ‘leiblich’, but also consists of a material dimension. This is established through the materiality of the human body and points beyond it at the same time. The material aspect of connectedness is not simply social but has a social meaning nonetheless: Materiality has an impact on society and on the quality of human coexistence with the environment. To be able to describe this aspect, we use approaches of feminist (neo-)materialisms. First, a neo-materialist perspective on subjectivity is developed, which, in addition to the immaterial aspects of the social, is also able to grasp the dependence of the development of human bodies on their environment. Connectedness as a material-discursive phenomenon adds a neo-materialist dimension to the established ‘phenomenological’ interpretation of the resonance concept that integrates interactions of repulsion or alienation by understanding feelings of alienation, rejection, or the silencing of the world-relationship as well as a resonant world-relationship always also as agentic cuts of the LeibKörper.
Stressors and learned resourcefulness in baccalaureate nursing students: a longitudinal study
Authors: Goff Anne-Marie 
Published: June 2023

Abstract

Objective
This correlational longitudinal study examined levels and relationships of Learned Resourcefulness (LR), stressors, and academic performance in baccalaureate nursing students at a North Carolina university.

Method
Gadzella‘s Student-life Stress Inventory (SSI) and Rosenbaum’s Self-Control Scale (SCS) administered to 85 students in two groups upon admission and graduation.

Results
LR increased, while stress decreased significantly in both groups (p < 0.05). Both groups (95.3% female, 85.8% Caucasian) reported similarly high frustration, pressure, and emotional reactions to stress. Significant relationship between taking tests and stress (p < 0.01). Stressors (p < 0.05) and age (p < 0.01) significant predictors of academic performance. Significant correlations of LR and work status (p < 0.01), and increased self-esteem (p < 0.05). No significant relationships among LR, stressors, and academic performance.

Conclusion
Results validate high levels of stress and suggest that higher LR enhances coping skills and decreases stress longitudinally, which can improve academic performance and retention.

Implications for International Audience
Trends and relationships in stressors and LR should be explored internationally in larger, more diverse samples of college students in nursing and other majors in relation to depression, anxiety, health-related behaviors, demographics, and academic performance. LR can be assessed, taught, learned, and enhanced. Greater numbers of qualified, competent nursing graduates with stronger clinical judgment, coping, and problem-solving skills will address the critical global nursing shortage and improve the quality, safety, and access of health care worldwide.
Kant’s “in itself”: Toward a New Adverbial Reading
Authors: Wolf W. Clark 
Published: June 2023

Abstract
It is commonly assumed that the expression “an sich selbst” (“in itself”) in Kant combines with terms to form complex nouns such as “thing in itself” and “end in itself.” I argue that the basic use of “an sich selbst” in Kant’s German is as a sentence adverb, which has the role of modifying subject-predicate combinations, rather than either subject or predicate on their own. Expressions of the form “S is P an sich selbst” mean roughly that S is P ‘in its own right’ or without some further ‘condition’. Accordingly, “an sich selbst” should not be treated as forming complex nouns. This analysis has significant consequences for the interpretation of “thing in itself” in particular, for it implies that the latter is not a complete nominal expression. Instead, one must treat ‘an sich selbst’ as expressing how some S is a ‘thing’, looking to the wider sentential context. I conclude with a brief account of the new significance granted to the concept of a ‘thing’ (Ding) according to the present interpretation.
The crystal structure of (S, R

p
)-4–benzhydrylideneamino-12-(4-tert-butyl oxazolin-2-yl)[2.2]paracyclophane, C36H36N2O
Authors: Chen Zhen , Sun Yanwen , Chen Chao , Xu Nuo , Wang Xiaozhong , Li Sijun 
Published: June 2023

Abstract

C
36

H
36

N
2

${\mathrm{C}}_{36}{\mathrm{H}}_{36}{\mathrm{N}}_{2}$

O, orthorhombic, P

2
1

2
1

2
1

${2}_{1}{2}_{1}{2}_{1}$

(no. 19), a = 11.849(2) Å, b = 14.373(3) Å, c = 17.183(3) Å, V = 2926.4(10)

Å
3

${\mathrm{\mathring{\text{A}}}}^{3}$

, Z = 4,

R

g
t

${R}_{\mathrm{g}\mathrm{t}}$

(F) = 0.0514, w

R

r
e
f

${R}_{\mathrm{r}\mathrm{e}\mathrm{f}}$

(

F
2

${F}^{2}$

) = 0.1272, T = 296(2) K.
The Metaphysical Contention of Political Theology
Authors: Carneiro Luís 
Published: June 2023

Abstract
The question of the exact role of theology in Schmitt’s political theology remains undecided. Several authors have raised this question and distinct answers have been given. In order to reach an accurate representation of the political–theological dimension in Schmitt’s work, I will attempt an interpretation which takes into account not only Schmitt’s more widely known theses, but also the perceived esoteric and unsaid aspects of his work. Against Heinrich Meier’s prominent thesis, in his The Lesson of Carl Schmitt, of the strict theological nature of political theology, my thesis is that Schmitt gives precedence to the political over theology and that political theology is a theology and metaphysics of the political. Starting from Peterson’s theological objections, centered on Trinitarian dogma and eschatology, I will reconstruct the trail of political theology throughout Schmitt’s work in view of its epitome in the notion of a Trinitarian stasiology and in the figure of the katechon. It is the connection between these two themes which defines Schmitt’s positive and polemical political theology, which can be designated as a katechontic and metastatic political theology. The katechon itself will be defined as the metapolitical and transcendental condition of possibility of the political. The Nomos of the Earth will also be a necessary reference point for the correct understanding of the connection between theology and politics, given the theme of “detheologization,” as well as Schmitt’s lifelong engagement with the problem of the state in the work of Thomas Hobbes.