bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lou et Rilke, l’ouverture du narcissisme
Authors: Bonnellier Roseline 
Published: January 2023

En 1899 et 1900, Lou Andreas-Salomé et Rainer Maria Rilke sont en Russie. L’auteur de cette étude se déplace entre poésie et psychanalyse. Elle propose une « ouverture du narcissisme » à l’autre, sur la base d’une remise en question de l’Œdipe freudien entre masculin et féminin.
Psychotraumatismes en situation d’exil
Authors: Lahya Samia , Arapian Christiane 
Published: January 2023

Les exilés accueillis en France présentent des facteurs vulnérabilité et pour beaucoup des symptômes de TSPT ou un SSPT Complexe. La clinique psychotraumatique en situation transculturelle nécessite de prendre en compte les représentations sociales de la maladie. Le sens donné aux symptômes peut être marqué par les croyances, rendant parfois difficile la formulation d’un diagnostic. En situation d’exil l’expression du TSPT est variable, à la fois individuelle et marquée par des représentations culturelles collectives. Au-delà des nosographies internationales, la prise en charge psychique des migrants ne peut être que transculturelle : les hypothèses diagnostiques et thérapeutiques restent ouvertes, évolutives et individualisées. Il s’agit de nommer le désordre dans son contexte, et d’adapter le soin aux représentations du patient. Un dispositif ambulatoire de soins psychiatriques dédiés a vu le jour en 2016 à Avignon : la Consultation Migrants Exilés Déplacés s’appuie sur les outils de la médiation ethnoclinique. Elle s’organise dans un esprit d’« aller vers » et dans une approche humaniste de la question psychotraumatique, tout en prenant en compte les croyances du patient et son système de représentation.
Regard critique sur une catégorie constitutionnelle
Authors: Gaillet Aurore 
Published: January 2023

Poser un « regard critique » sur la « catégorie » du semi-présidentialisme n’a rien de spécialement original. Le constat de sa persistance n’en suscite pas moins un étonnement, apte à interroger les constitutionnalistes, plus encore lorsqu’ils enrichissent leur regard critique d’une dimension comparée. La contribution proposée intègre une perspective franco-allemande pour porter un triple regard critique, visant successivement : la catégorie elle-même, laquelle échoue à s’imposer pour dépasser la distinction binaire qui oppose régimes parlementaires et présidentiels ; la problématique plus large des catégories constitutionnelles ; et, enfin, la V e République, objet privilégié des études françaises sur le semi-présidentialisme.
De la transition démocratique à la démocratie autoritaire : l’expérience taïwanaise du semi-présidentialisme
Authors: Chen Chwen-wen 
Published: January 2023

Le régime semi-présidentiel, choisi pour sa plasticité par l’élite taïwanaise, a-t-il réellement permis de passer de l’autocratie à la démocratie ? Il a sans nul doute ouvert une nouvelle ère à Taïwan, mais l’élection populaire du chef de l’État, en neutralisant l’effet des garde-fous constitutionnels, a fait surgir un monarque quasi indomptable.
Les partis politiques par temps de plateformes
Authors: Greffet Fabienne 
Published: January 2023

L’introduction de ce dossier de Réseaux portant sur les partis plateformes et plateformes politiques présente les travaux récents concernant les appropriations des plateformes numériques au sein des organisations politiques. Trois grands types de plateformes sont identifiés : les plateformes de mobilisation électorale, implantées au sein des partis existants ; les plateformes configuratrices des organisations politiques, qui concernent des partis structurés autour du numérique, dont le projet politique implique une rupture avec les structures organisationnelles des partis classiques ; enfin, les plateformes citoyennes, qui font disparaître la forme-parti pour organiser la prise en charge numérique, par les citoyens, de la désignation des candidats aux élections. L’article propose ensuite une discussion autour de l’émergence d’un nouveau type de parti, le parti plateforme, théorisé par Paolo Gerbaudo. Il montre que la controverse autour de cette notion est indicative des tensions qui traversent le champ des sciences sociales du numérique. Enfin, un résumé des papiers présents dans le numéro est proposé.
Quercetin modulates ovarian autophagy–related molecules and stereological parameters in a rat model of PCOS
Authors: Neisy Asma , Koohpeyma Farhad , Khorchani Majid Jafari , Karimi Fatemeh , Zal Fatemeh 
Published: January 2023

Objective:
To examine the effect of quercetin on stereological parameters and autophagy-related genes in ovaries of polycystic ovary syndrome (PCOS) rats.

Methods:
Fifty female Sprague-Dawley rats were randomly divided into five groups: the control group, the ethanol group, the quercetin group (15 mg/kg/day), the PCOS group, as well as the PCOS + quercetin group. After the induction of PCOS, quercetin was administered orally for 30 days. Histological, stereological and real-time PCR analyses were carried out to evaluate the effect of quercetin on PCOS rats.

Results:
Stereological analysis revealed that quercetin significantly increased the number of ovarian follicles and the volume of corpus luteum and induced a significant decrease in atretic follicles in comparison to the PCOS group. In addition, quercetin markedly increased mTOR gene expression while decreasing Beclin-1 and LC3 gene expression.

Conclusions:
Quercetin strongly modulates the expression of ovarian autophagy-related genes and stereological parameters in PCOS rats. Therefore, it can be considered as an ameliorative component for ovarian follicular impairments.
Estimation of Stress amongst the Parents of Neonates Admitted to Neonatal Intensive Care Unit
Authors: Sisodia Pragati , Khan Haseeb , Shukla Nirpal Kaur , Rathoria Richa , Rathoria Ekansh , Bansal Utkarsh , Shukla Ram 
Published: January 2023

Introduction:
The admission of the baby to the neonatal intensive care unit (NICU) can be a stressful predicament for parents. This study aims to evaluate parental stress levels and the factors impacting them.

Materials and Methods:
This cross-sectional study was conducted in the NICU of a tertiary care centre for 3 months. Data were collected using a questionnaire consisting of demographic characteristics of parents, neonates and Parental Stressor Scale: NICU (PSS: NICU) to measure parental stress. The data were analysed using descriptive statistics and an independent t-test.

Results:

P ≤ 0.05 was considered statistically significant. Most of the parents reported medium stress levels (3–3.9). The mean total parental stress score of parents was 3.31 (0.36). Amongst the PSS: NICU subscales, the NICU sight and sound caused maximum stress to the parents (mean = 3.35 [0.48]) followed by the relationship with the baby and parental role (mean = 3.34 [0.44]). Mothers felt more stressed as compared to fathers (mean = 3.60 [0.23] vs. 3.08 [0.28]; P < 0.05).

Conclusion:
Higher parental stress levels were seen in lower age group (18–25 years), less than high school education, unemployed and previous history of neonatal death, outborn deliveries, pre-term (gestational age <37 weeks), birth weight <1500 g, longer duration of respiratory support (>3 days), intubated with ventilatory support, not started on feeds and not given kangaroo mother care. Parents of NICU-admitted neonates are under significant stress, and there is a necessity to provide family-centred care.
Impact of Online Learning during the COVID-19 Pandemic on Medical Students and Faculty Members: A Cross-Sectional Study from Majmaah University, Saudi Arabia
Authors: Lateef Junaid Mohammed Abdul , Sami Waqas , Aldhafiri Hamad J , Alabdulmonyem Jehad A , Alenazi Abdulkarim K , Kaseb Ahmed 
Published: January 2023

Introduction:
During the ongoing COVID-19 pandemic, all prospective of life have been affected by the situation. As a result of which, many universities adopted the online way of teaching instead of the traditional classroom teaching or by blending both together. This study was carried out with the objective to assess the perception of teachers and students regarding classes taken online versus those taken in the classroom.

Materials and Methods:
A descriptive cross-sectional study was carried out among students and faculty members of the medical college at Majmaah University, KSA, from October 2020 to April 2021.

Results:
The study found that the majority of teachers have disagreed (91%) that online classes were more effective than classroom mode, and regarding the overall perception of teachers for classes taken online and in the classroom, 62% of teachers agreed that online classes were better than classroom mode, whereas 38% disagreed; 61% of students agreed that online classes were better than classroom mode, and 39% disagreed.

Conclusion:
Educational institutions should be ready to handle pandemic-like situations without disrupting educational activities and to achieve this, appropriate training of the faculty members and students should be carried out to make online teaching effective and also to minimise any associated disturbing factors.
Assessment of Risk Factors in Pyogenic Liver Abscesses in Children
Authors: Pandey Anurag , Rajeshwari K. , Kumar Deepak , Gupta Garima 
Published: January 2023

Background:
Pyogenic liver abscess (LA) is a significant contributor to morbidity and mortality in developing countries like India. The risk factors predisposing to the LA specifically in children are not known. Studies done in the past largely remain inconclusive and have identified only probable causes. The cause of LA in children with no coexisting illness remains unknown.

Methodology:
This prospective observational study was conducted at a tertiary teaching hospital located in New Delhi, India. All children between 2 months and 12 years of age with sonographically confirmed LA presenting to the hospital were included and managed with appropriate intravenous antibiotics and relevant investigations.

Results:
A total of 52 children were included. The mean age was 6 years and 4 months, and the male: female ratio was 1.4:1. Around 50% of the patients were malnourished. Fever, abdominal pain and loss of appetite were the most common symptoms. Nine patients (17%) were managed conservatively, 13 (25%) needed percutaneous needle aspiration and 30 (57.69%) required drainage using a pigtail catheter. Poor socioeconomic status and anaemia were found to be the most commonly associated risk factors. Selective immunoglobulin A (IgA) deficiency was the most common primary immunodeficiency disorder followed by T-cell defect. On multivariate analysis, it was seen that in those with clinical icterus, gamma-glutamyl transferases >350 IU/m, and those with impending rupture, the time to defervescence was significantly different (P = 0.05).

Conclusion:
Poor socioeconomic status causing malnutrition emerged as a significant risk factor for LA in children. Selective IgA deficiency was the most common immunodeficiency seen in a few children. Adopting a conservative approach like aspiration and percutaneous drainage led to lower mortality and good recovery rates.
Treatment of Long Bone Fractures in Children by Elastic Stable Intramedullary Nailing: Outcome and Challenges in a Unit with Restricted Technical Platform
Authors: Goudjo Eudes Ulrich Elvis Mahougnon , Metchihoungbe Codjo Serge , Mihluedo-Agbolan Anani Komlan , Houegban Amoussou Sedjro Clotaire Romeo , Teko Dede Virginie , Miaffo Octave Exupere Desire Dongmo , Gnassingbe Komla 
Published: January 2023

Introduction:
Elastic stable intramedullary nailing (ESIN), developed by the Nancy school in France, is the gold standard for surgical treatment of long bone fractures in children. In Africa, few works have been devoted specifically to this technique.

Objective:
This study aimed to describe the outcome and to present the challenges with this technique in the treatment of long bone fractures in children.

Patients and Methods:
This was a prospective and descriptive study over 4 years including patients aged 0–15 years old operated using ESIN.

Results:
Sixty-two patients underwent ESIN, of whom 44 patients (70.96%) were for femur fractures, nine patients (14.52%) for tibia and fibula fractures and nine patients (14.52%) for humerus fractures. The majority of the patients treated with ESIN were children older than 6 years. Nine patients (14.51%) and 13 patients (20.98%) underwent ESIN following polytrauma and multiple fractures, respectively. Seven patients (11.29%) were operated on through-closed ESIN method. The unavailability of image intensifier (38.71%) and the presence of bone callus (40.32%) were the major reasons for using the open ESIN method. Thirty-three patients (53.23%) had minor or major complications. The majority of patients had satisfactory therapeutic outcomes.

Conclusion:
ESIN gives good results, even when the fracture site is approached.
Association between Intraoperative Anatomical Variation and Histopathological Parameters in Cases of Ureteropelvic Junction Obstruction in Children: A Cross-Sectional Study
Authors: Solanki Shailesh , Menon Prema , Reddy Manasa , Parkhi Mayur , Gupta Kirti , Gupta Pramod K , Peters Nitin James , Samujh Ram 
Published: January 2023

Introduction:
The intraoperative anatomical findings (IOAF) of all ureteropelvic junction obstruction (UPJO) cases are not identical. Moreover, there is also controversy in the literature regarding histopathological (HP) findings in cases of UPJO. In the present study, we evaluated different IOAF and assessed their association with specific HP parameters.

Materials and Methods:
This was a cross-sectional study set-up, which was carried out in a tertiary care centre. Children with UPJO who underwent surgery between 2017 and 2020 were enrolled. The following IOAF were noted: Type of pelvis (extrarenal or intrarenal), insertion of the ureter (high or normal), presence of lower pole crossing vessel (CV), negotiation of UPJ segment with double J stent (3 Fr) and length of internal narrowing (LIN) at UPJ. The resected segment of UPJ was assessed at three levels (pelvis, UPJ and ureter) for various HP parameters including fibrosis, oedema, inflammation and smooth muscle hypertrophy (SMH).

Results:
Thirty-nine children were included in the study with a mean age of 31 months. The summary statistics of IOAF were intrarenal pelvis in 5 cases, high insertion of the ureter (HIU) in 9, CV in 6, negotiable UPJ in 23, and 16 cases showed LIN >1 cm. All cases showed SMH at the pelvis region and SMH with fibrosis at the UPJ region. At the pelvis region, there was an association between (1) HIU with oedema and chronic inflammation (CIF), (2) CV with CIF and (3) LIN with CIF and SMH. At the UPJ region, there was an association between (1) CV and negotiable UPJ with less fibrosis and (2) LIN with SMH. At the ureteric end, CV showed an association with less fibrosis and more CIF.

Conclusion:
All UPJO cases have some common HP findings. Although, some particular IOAF, i.e., presence of CV, negotiable UPJ, HIU and LIN showed association with specific HP parameters.
Health-related Quality of Life of Children with Gastro-oesophageal Reflux Disease after Nissen Fundoplication and Gastrostomy Tube Insertion
Authors: Musibi Felix , Mugambi Machoki , Samia Pauline , Nganga Waceke 
Published: January 2023

Introduction:
Severe gastro-oesophageal reflux disease (GERD) is associated with a poor health-related quality of life (HRQoL). Nissen fundoplication is the most common surgical procedure for patients with GERD. A feeding gastrostomy tube may be inserted at the same time in selected patients where there are unsafe swallowing and/or feeding difficulties. The goals of surgery are to eliminate symptoms, prevent reflux complications and ultimately improve the quality of life. The main objective of this study was to assess the HRQoL of children with GERD after Nissen fundoplication and gastrostomy tube insertion.

Materials and Methods:
This was an observational retrospective cohort study at two private, not-for-profit tertiary hospitals in Nairobi. The study population included children under 18 years of age with GERD who had Nissen fundoplication with or without gastrostomy tube insertion from January 2010 to December 2020. The quality of life was assessed from the caretakers using the Paediatric Quality of Life Inventory applied through a telephone call. Data analysis was done using SPSS version 26. The HRQoL was summarised using mean and standard deviation (SD) with a 95% confidence interval (CI) around the scores. Independent samples t-test was conducted to compare the means of HRQoL for gender, complications and comorbidities. Spearman’s correlation was done for HRQoL and age.

Results:
Eighty-two children were included in the study. Eighty-four per cent had comorbidities, with almost three-quarters of them having neurological impairment. Majority (91%) had open Nissen fundoplication, while 9% had laparoscopic Nissen fundoplication. One-third of these children reported complications post-procedure. Nissen fundoplication failure rate was 10%. Two-thirds had a concurrent gastrostomy tube insertion. The global mean HRQoL score was 75.8 (SD: 23.5, 95% CI: 70.4–81.2). Gastrostomy tube insertion had no impact on the quality of life. Children with neurological impairment had significantly lower quality of life than those without neurological impairment.

Conclusion:
The global score of the HRQoL following Nissen fundoplication in this cohort of children was 75.8. Further studies to reduce the proportion of children who experience complications postoperatively in this setting are required.
Pull-Through of Ganglionic Stoma in Children with Hirschsprung’s Disease Living in a Low Resource Context Spares Further Surgery for Colostomy Reverse
Authors: Tresphory Boniphace , Mlawa Agnes , Calisti Alessandro 
Published: January 2023

Background and Aims:
One-step pull-through for Hirschsprung’s disease (HSCR) is already standard in many tertiary African paediatric surgical centres where radiology and frozen sections are available. However, limited resources in many peripheral areas associated with advanced age at referral or complicated presentation make recourse to colostomy often unavoidable with a consequent three-step surgery. To simplify these children’s clinical course and spare the burden of a third procedure for colostomy reverse, a direct pull-through of the proximal ganglionic stoma is proposed.

Methods:
Twenty children (male/female ratio 19/1) between 3 months and 13 years with a colostomy for a suspected HSCR were selected for stoma pull-through among patients admitted to a regional Tanzanian hospital between 2016 and 2022. Histological diagnosis was always confirmed by rectal biopsies and, in some cases, colonic specimens taken during the stoma confection or revision. A ganglionic stoma was always ascertained before the pull-through procedure (11 Transanal Endorectal, 4 Soave and 5 Duhamel).

Results:
One death was registered in a child with Down syndrome, unrelated to surgery, and another due to HSCR acute associated enterocolitis. One stenosis required stricturoplasty, and one anastomotic leakage needed temporary ileostomy. No relationship was found between complications and the procedure of choice. Passage of stools started on the 2nd day and became regular and without soiling in a week. Conclusions: Straightforward pull-through of the ganglionic stoma may be a feasible solution for patients with HSCR and a diverting colostomy to avoid a three-step procedure. The correct position of the stoma at the transition zone must be ascertained to avoid the risk of including in the resection segment of the ganglionic bowel.
Hylocereus undatus fruit extraction on percent yield using Design-Expert software
Authors: Ahad Hindustan A. , Chinthaginjala Haranath , Tarun Ksheerasagare , Reddy Gummadisani G. , Adam Adam A.O. , Ali Abdelrahaman I. , Krishna Jyothi V. 
Published: January 2023

Background
Dragon fruits (Hylocereus undatus) are popular edible fruits of desert and dry-land origin. They are rich in constituents. An attempt was made to find the optimum temperature and duration of exposure for the effective extraction of content from the fruits using Design-Export software.

Aim
This study aims to see what effect temperature and duration have on dragon fruit (H. undatus) extraction. According to the literature, numerous attempts have been made to extract components from fruits and other plant parts.

Materials and methods
The authors made an attempt to check if independent variables had an effect on the dependent response. The Design-Expert software was used to control the impact of the independent variable on the response during the experiment’s design. Alternatively, samples were positioned, authenticated, and hauled out into the water, with independent factors (temperature and exposure time) affecting the response (percent yield).

Results and conclusions
According to the study, 40°C is the ideal temperature to extract the substance from the fruits, and the extraction and exposure times are directly proportional.
Acute effects of online hemodiafiltration versus high-flux hemodialysis on serum levels of asymmetric dimethylarginine and tumor necrosis factor-alpha
Authors: Elsayed Hesham M. , El Said Heba W. , Beshary Waleed A. , Jaleel Ahmed A. , Ahmed Fatma A 
Published: January 2023

Background
Chronic inflammation as a major determinant of ‘dialysis syndrome’ is considered as the main factor of morbidity and mortality in dialysis patients. Tumor necrosis factor-alpha (TNF-α) may play important roles in the development of T helper (Th) imbalance, cardiovascular disease, and wasting in the uremic milieu. Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide that may be an independent risk factor for endothelial dysfunction and cardiovascular disease. In hemodialysis (HD) patients, plasma ADMA is a strong and independent predictor of overall mortality and cardiovascular outcome. The aim of this study to evaluate the acute effects of hemodiafiltration (HDF) compared with conventional HD on blood levels of ADMA and TNF-α.

Patients and methods
A cross-sectional study was conducted on 20 patients with end-stage renal disease receiving dialysis in the dialysis unit of Ain Shams Specialized Hospital receiving twice weekly HD session with high-flux (HF) dialyzer and once weekly HDF session. Blood samples were collected from all participants before and after HD session and from the same participants before and after HDF session. ADMA and TNF-α levels were assessed by enzyme-linked immunosorbent assay techniques.

Results
The decrease in TNF-α was higher after HDF session versus HF HD session (79.47 ± 14.16 vs. 50.43 ± 31.05), with P value of 0.001. Moreover, the decrease in ADMA was higher after HDF session versus HF HD session (75.01 ± 12.55 vs. 41.79 ± 24.73), with P value of 0.001.

Conclusion
The use of online HDF technique showed a significant reduction of ADMA and TNF-α in adults with end-stage renal disease.