bluuebunny/crossref_metadata_2025_split huggingface dataset:
Machine Learning–Based Prediction of Substance Use in Adolescents in Three Independent Worldwide Cohorts: Algorithm Development and Validation Study
Authors: Kim Soeun , Kim Hyejun , Kim Seokjun , Lee Hojae , Hammoodi Ahmed , Choi Yujin , Kim Hyeon Jin , Smith Lee , Kim Min Seo , Fond Guillaume , Boyer Laurent , Baik Sung Wook , Lee Hayeon , Park Jaeyu , Kwon Rosie , Woo Selin , Yon Dong Keon 
Published: January 2025

Background
To address gaps in global understanding of cultural and social variations, this study used a high-performance machine learning (ML) model to predict adolescent substance use across three national datasets.

Objective
This study aims to develop a generalizable predictive model for adolescent substance use using multinational datasets and ML.

Methods
The study used the Korea Youth Risk Behavior Web-Based Survey (KYRBS) from South Korea (n=1,098,641) to train ML models. For external validation, we used the Youth Risk Behavior Survey (YRBS) from the United States (n=2,511,916) and Norwegian nationwide Ungdata surveys (Ungdata) from Norway (n=700,660). After developing various ML models, we evaluated the final model’s performance using multiple metrics. We also assessed feature importance using traditional methods and further analyzed variable contributions through SHapley Additive exPlanation values.

Results
The study used nationwide adolescent datasets for ML model development and validation, analyzing data from 1,098,641 KYRBS adolescents, 2,511,916 YRBS participants, and 700,660 from Ungdata. The XGBoost model was the top performer on the KYRBS, achieving an area under receiver operating characteristic curve (AUROC) score of 80.61% (95% CI 79.63-81.59) and precision of 30.42 (95% CI 28.65-32.16) with detailed analysis on sensitivity of 31.30 (95% CI 29.47-33.20), specificity of 99.16 (95% CI 99.12-99.20), accuracy of 98.36 (95% CI 98.31-98.42), balanced accuracy of 65.23 (95% CI 64.31-66.17), F1-score of 30.85 (95% CI 29.25-32.51), and area under precision-recall curve of 32.14 (95% CI 30.34-33.95). The model achieved an AUROC score of 79.30% and a precision of 68.37% on the YRBS dataset, while in external validation using the Ungdata dataset, it recorded an AUROC score of 76.39% and a precision of 12.74%. Feature importance and SHapley Additive exPlanation value analyses identified smoking status, BMI, suicidal ideation, alcohol consumption, and feelings of sadness and despair as key contributors to the risk of substance use, with smoking status emerging as the most influential factor.

Conclusions
Based on multinational datasets from South Korea, the United States, and Norway, this study shows the potential of ML models, particularly the XGBoost model, in predicting adolescent substance use. These findings provide a solid basis for future research exploring additional influencing factors or developing targeted intervention strategies.
Network Pharmacology and Molecular Mechanism of Traditional Indonesian Medicine in Hypertension Treatment
Authors: Setiani Lusi Agus , Saputri Fadlina Chany , Yanuar Arry , Mun’im Abdul 
Published: January 2025

Scientific herbal formulations are used clinically to treat hypertension, but their functional molecular mechanisms remain to be elucidated. This study was identified the molecular pathways by which scientific herbal remedies for treating hypertension work. The identified compounds were then excluded by measuring oral bioavailability and drug similarity. The network was created using Cytoscape version 3.8, and the predicted target information was obtained from a number of databases, including SwissTarget Prediction, STRING, Online Mendelian Inheritance in Man (OMIM), and Kyoto Encyclopedia of Genes and Genomes (KEGG). The decoction’s method for lowering hypertension was then clarified using an enrichment analysis. It was discovered that bioavailability and drug similarity metrics existed for a total of 44 identified substances. The results of pathway analysis using KEGG revealed that the potential targets were correlated antihypertensive mechanism of herbal medicine such as the HIF-1 signaling pathway, Relaxin signaling pathway, PI3K signaling pathway, and MAPK signaling pathway. Scientific herbal formulas' pressure-lowering mechanisms include those related to vascular endothelium and atherosclerosis, which involve several signaling pathways such as the HIF-1 signaling pathway, the Relaxin signaling pathway, the PI3K signaling pathway, and the MAPK signaling pathway.
Perspectives and Experiences of Patients with AKI
Authors: Natale Patrizia , Wu Rebecca , Hughes Anastasia , Sluiter Amanda , Rubenstein David Ari , Zappitelli Michael , Povoa Pedro , Morris Andrew Conway , O’Connor Jillian , Teixeira-Pinto Armando , Strippoli Giovanni , Jaure Allison 
Published: January 2025

Key Points

Six themes have been identified reflecting the perspectives and experiences of adults with AKI.Patients are unaware of AKI diagnosis and prognosis, feel that care is fragmented, and are burdened by treatment.Providing education, reducing treatment burden, and ensuring excellence in care may help to address patients' needs and improve AKI management.

Background
AKI is associated with higher risk of mortality and progression to CKD. The challenges and uncertainty in the diagnosis, self-management, and prevention of AKI can be distressing for patients. We aimed to perform a systematic review of qualitative studies/surveys that reported the perspectives and experiences of adults with AKI.

Methods
We searched MEDLINE, Embase, PsycINFO, and CINAHL from inception to January 17, 2024. Thematic textual analysis was used to synthesize the findings.

Results
We included 20 studies (ten qualitative studies, ten surveys) involving 867 participants. We identified six themes: navigating the unknown (an unexpected and unfamiliar diagnosis, tossed about in a fragmented system, and dismissed and vulnerable at discharge); impaired life participation, relationships, and well-being (limiting ability to do daily activities and straining relationships); unbearable and unsustainable treatment burden (adding strain on family members, financial pressure because of medical expenses, and cumulative stress of ongoing monitoring); uncertain whether recovery is attainable (possible permanence of kidney damage, fear about nephrotoxic medications, and terrified about the need for dialysis); less consequential than other health priorities (short term and reversible and prioritizing other comorbidities and conditions); and empowered in managing own health (focusing on optimizing kidney health, gaining confidence in self-management, and reassured with social and clinical support).

Conclusions
Patients may be unaware of their AKI diagnosis and prognosis, feel that care is fragmented, and be burdened by treatment. Providing education, alleviating treatment burden, and implementing a comprehensive model of care may help to address the needs of patients with AKI leading to better outcomes.
PERAN EKSTRAKURIKULER MALIM SEKAMPUNG DALAM MENANAMKAN NILAI-NILAI IBADAH KEPADA SISWA DI MTsN TANJUNGBALAI
Authors: Manurung Ahda , Nasution Wahyudin Nur , Pulungan Enny Nazrah 
Published: January 2025

Penelitian ini dilatarbelakangi ketertarikan terhadap ekstrakurikuler Malim Sekampung di MTsN Tanjungbalai. terkait pengurusan jenazah (fardhu kifayah) dan pelatihan doa/wirid bagi siswa masih jarang ditemui di sekolah khususnya di Tanjungbalai. Penelitian menggunakan metode peneliitan kualitatif. pendekatan fenomenologis dan bersifat penelitian lapangan (field research) dengan model analisis deskriptif. Teknik pengumpulan data menggunakan observasi, wawancara dan dokumentasi. Analisis data dilakukan yaitu melalui reduksi data, penyajian data dan penarikan kesimpulan. Hasil penelitian menunjukkan bahwa bentuk-bentuk kegiatan ekstrakurikuler Malim Sekampung di MTsN Tanjungbalai yaitu diantaranya: 1) Pengurusan jenazah (Fardhu Kifayah) dan 2) Pelatihan doa-doa takziah dan wirid. Metode pembina dalam pelaksanaan Ekstrakurikuler Malim Sekampung yaitu melalui 1) metode ceramah, 2) metode demonstrasi, 3) metode praktik dan 3) metode keteladanan/uswatun hasanah. Evaluasi yang dilakukan yaitu evaluasi ranah kognitif yaitu melalui tes tertulis (multiple choice) dan tes lisan. Evaluasi ranah psikomotorik yaitu melalui tes unjuk kerja/praktik. Faktor Pendukung yaitu meliputi: (1) kepribadian dan cara mendidik pembina, (2) dukungan pihak sekolah, (3) Motivasi dari orangtua. faktor penghambat ekstrakurikuler yaitu adanya beberapa jadwal esktakurikuler siswa yang bertabrakan keterbatasan event dan lomba yang mampu menunjang semangat siswa pada bidang keagamaan tersebut yaitu fardhu kifayah dan perlombaan doa/wirid dan itu terus diupayakan.
Impact of Soil Use On Winter Greenhouse Gas Emissions: The Agricultural Sector in Alagoas Through An Emissions Inventory
Authors: Silva Anderson Jefferson Gomes da , Mariano Glauber Lopes , Alonso Marcelo Felix , Gomes Heliofábio Barros , Silva Fabrício Daniel dos Santos 
Published: January 2025

Objective: To prepare a greenhouse gas inventory within the state of Alagoas for 2019, using data and factors from livestock and agriculture.

Theoretical framework: Preparing an inventory is an important tool for understanding climate change that is directly related to greenhouse gas (GHG) emissions, mostly resulting from anthropogenic activities. In Brazil, agriculture stands out as one of the main sources of emissions, driven by the production of grains and animals for domestic and foreign consumption. Due to the difficulty of direct measurement, emissions are often assessed through inventories. The GHG emissions inventory is one of the basic tools that provides relevant data to direct certain public policies, or civil society actions, to reduce GHG emissions into the atmosphere, given that the state of Alagoas has few scientific productions on GHG sources and emissions.

Methodology: Emissions were calculated by multiplying the emission coefficient following the methodology proposed by the IPCC, GHG Protocol, using the multiplication of the emission coefficient also indicated by the IPCC, MCTIC, EMBRAPA by the total number of heads or by the number of hectares of each crop in 2019 to calculate emissions. The results were then transformed into figures to facilitate understanding and analysis.

Results and Discussions: N2O emissions from temporary and permanent crops, and N2O and CH4 emissions from flooded rice crops; as well as CH4 and N2O emissions from the livestock sector, totaling 10.53 MtCO2e of emissions in 2019. Comparing with other results, differences were noted in the total emissions due to the adoption of different methodologies and factors, as well as in what to measure, so this article presents advances and limitations, contributing to a greater depth of understanding of emissions.

Research Implications: This research contributes to the scientific literature, public policy actions and environmental planning, as well as understanding and analyzing the impacts on the agricultural sector, and methodological and scientific advances, and the promotion of new research and data updates that can guide new research and updates.

Originality/value: This study provides a regional focus on Alagoas, with consistent applications of international methodologies (IPCC, GHG Protocol) in local contexts. It serves as a basis for local public policies, environmental and climate impacts, expanding knowledge about the state's emissions, and encouraging innovation in local methods, as well as awareness and social mobilization.
Sustainability Strategy in the Development of Msmes by Bank Indonesia in Increasing Economic Growth by Using Green Economic Policy as an Intervening Variable
Authors: Hadi Dwi Prastiyo , Riyanto  , Wahyuhastuti Novika , Wuryandini Endang , Putra Fajar Darma 
Published: January 2025

Objective: The main objective of this study is to assess the impact of Bank Indonesia's MSME Development program on economic growth, with a specific focus on the role of green economic policies as an intervening variable. This research seeks to identify key factors that contribute to the sustainability and growth of MSMEs in Indonesia.

Theoretical Framework: This study draws upon theories of sustainable economic development, focusing on the role of green economics in business sustainability. The framework integrates concepts from corporate sustainability, economic growth, and environmental policy, exploring how MSMEs can leverage green practices to boost economic performance.

Method: A mixed-method approach was employed, combining quantitative analysis of survey data and statistical tests with qualitative methods such as interviews and case studies. The quantitative analysis examines the direct and indirect effects of the MSME development program, while the qualitative analysis provides deeper insights into the processes and challenges faced by MSMEs in adopting green economic policies.

Results and Discussion: The findings indicate that MSMEs that implement Bank Indonesia's MSME development program experience significant positive effects on economic growth. These effects are further enhanced when green economic policies are incorporated into MSME practices. Specifically, the research identifies several key factors contributing to growth 1.Corporate Structuring: Positive impact on economic growth through the establishment of stronger business foundations, 2.Capacity Building: Expansion of business capabilities leads to improved performance and sustainability,3. Market Expansion: Broader market access fosters economic resilience and growth, 4.Outboarding: The adoption of outboarding strategies leads to improved international competitiveness, 5.Intervening Role of Green Economic Policies: Green policies significantly enhance the effects of MSME development initiatives, contributing to greater economic stability and growth.

Research Implications:. This research highlights the importance of integrating green economic policies in MSME development programs, providing a roadmap for policymakers to design sustainable growth strategies. By focusing on sustainability, MSMEs can not only contribute to economic growth but also support broader environmental and social goals..

Originality/Value: This study is one of the first to explore the intersection of MSME development, economic growth, and green economic policies in the context of Indonesia. It contributes valuable insights into how sustainable practices can be integrated into MSME strategies to foster long-term economic resilience..
Совершенствование нормативного правового регулирования запрета разглашать или использовать в целях, не связанных с гражданской службой, служебную информацию.
Authors: Сёмин А.Н. 
Published: January 2025

Статья посвящена исследованию правовых и фактических оснований установления, а также особенностей реализации запрета государственным гражданским служащим разглашать или использовать в целях, не связанных с гражданской службой, служебную информацию. В рамках работы проведен общий анализ условий для сужения объема прав и свобод лиц, замещающих должности государственной гражданской службы, а также исследованы теоретические и практические подходы к классификации и оценке информации, получаемой госслужащими в процессе исполнения должностных обязанностей. Примененный подход позволил выявить пробелы и противоречия в действующем нормативном правовом регулировании государственной гражданской службы и терминологическом аппарате, предложить пути их восполнения, а также доказать необходимость совершенствования различных элементов должностной структуры государственной гражданской службы Российской Федерации, в целях обеспечения соблюдения баланса между общественными интересами и правами и свободами лиц, замещающих должности гражданской службы.
The article is devoted to the study of the legal and factual grounds for establishing and features of implementing the ban for civil servants to disclose or use official information for purposes not related to civil service. The work includes both a general analysis of the conditions for narrowing the scope of rights and freedoms of persons occupying civil service positions, and a study of theoretical and practical approaches to the classification and assessment of information received by civil servants in the process of performing official duties. The applied approach made it possible to identify gaps and contradictions in the current regulation and terminology, propose ways to fill them, and prove the need to improve various elements of the organizational structure of the civil service of the Russian Federation in order to ensure a balance between public interests and the rights and freedoms of persons occupying civil service positions. Keywords: civil service; information rights; restrictions and bans; organizational structure; official information
Криминалистическая характеристика преступлений как информационная основа для создания автоматизированных программ
Authors: Валькирия Н.И. 
Published: January 2025

Цель исследования — определение актуальных проблем криминалистической характеристики преступлений в современных условиях развития цифровых технологий и путей их решения. Для достижения данной цели использовался комплекс методов (анализ, синтез, индукция, дедукция, сравнение, моделирование и др.), позволивший выявить и исследовать ряд теоретических и практических вопросов сквозь призму решения задачи по созданию специальных программ, информационной основой которых является криминалистическая характеристика преступлений. Преимуществом данных программ отмечена не только автоматическая обработка эмпирического материала и выявление типичных взаимосвязей между элементами криминального события, но и возможность построения криминалистической модели неизвестного преступника при расследовании конкретного преступления. В целях совершенствования работы по формированию программ, основанных на применении алгоритмов искусственного интеллекта и методов математической статистики, первоочередной задачей указана необходимость уточнения и конкретизации информационного содержания элементов криминалистической характеристики преступлений как поисковых модулей данных программ.
The purpose of the study was to determine the actual problems of criminalistic characterization of crimes in the modern conditions of digital technology development and to identify ways to solve them. To achieve this goal, we used a set of methods (analysis, synthesis, induction, deduction, comparison, modeling, etc.), which allowed us to identify and investigate a number of theoretical and practical issues through the prism of solving the problem of creating special programs, the information basis of which is the criminalistic characterization of crimes. The advantage of these programs noted not only automatic processing of empirical material and identification of typical relationships between the elements of the criminal event, but also the possibility of building a forensic model of an unknown criminal in the investigation of a particular crime. In order to improve the work on the formation of programs based on the application of artificial intelligence algorithms and methods of mathematical statistics, the need to clarify and specify the information content of the elements of the criminalistic characteristics of crimes as search modules of these programs is a priority.
К вопросу о формах денежных средств: цивилистические аспекты
Authors: Клочихин В.А. 
Published: January 2025

Статья посвящена исследованию различных форм денежных средств в цивилистическом аспекте с целью дальнейшего развития правового регулирования безналичных расчетов с участием банковских структур. Большое внимание автор уделяет соотношению понятий электронных и цифровых денежных средств. Цифровой рубль автор относит к безналичным денежным средствам. Ключевые слова: форма денег, безналичные деньги, электронные денежные средства, цифровые рубли, металлические монеты, бумажные банкноты, криптовалюта.
The article is devoted to the study of various forms of money in the civilistic aspect with the aim of further development of legal regulation of non-cash payments involving banking structures. The author pays much attention to the relationship between the concepts of electronic and digital money. The author classifies the digital ruble as non-cash money.
Заключение под стражу субъекта предпринимательской деятельности при хищении бюджетных средств
Authors: Григорьева Н.В. 
Published: January 2025

В статье рассматриваются отдельные аспекты избрания таких мер процессуального принуждения, как заключение под стражу и запрет определенных действий предпринимателям, совершившим хищение бюджетных средств. Отмечается необходимость при избрании меры принуждения в виде запрета определенных действий конкретизации круга лиц, общение с которыми возможно. Резюмируется, что при хищении бюджетных средств правоприменительная практика имеет основание для избрания меры принуждения в виде заключения под стражу.
The article examines certain aspects of choosing such measures of procedural coercion as detention and prohibition of certain actions for entrepreneurs who have committed theft of budget funds. It is noted that when choosing a coercive measure in the form of a prohibition of certain actions, it is necessary to specify the circle of persons with whom communication is possible. It is summarized that in the case of theft of budget funds, law enforcement practice has grounds for choosing a coercive measure in the form of detention.
Понятие и элементы правового статуса граждан как субъектов обеспечения обороны страны и безопасности государства
Authors: Федотова Ю.Г. 
Published: January 2025

Рассматриваются понятие и элементы правового статуса граждан как субъектов обеспечения обороны страны и безопасности государства. На основании анализа доктринальных взглядов, законодательства и судебной практики автор приводит перечень элементов правового статуса граждан, выявлены их особенности и взаимосвязи, раскрыты правовые меры, применяемые к гражданам как субъектам обеспечения обороны и безопасности.
The article examines the concept and elements of the legal status of citizens as subjects of ensuring the country's defense and state security. Based on the analysis of doctrinal views, legislation and judicial practice, the author provides a list of elements of the legal status of citizens, identifies their features and interrelations, and discloses legal measures applied to citizens as subjects of ensuring defense and security.
О некоторых изменениях уголовно-правовой политики в сфере противодействия налоговым преступлениям
Authors: Батюкова В.Е. 
Published: January 2025

Анализируются основные направления уголовно-правовой политики в сфере противодействия налоговым преступлениям. Подвергается анализу судебная статистика по налоговым преступлениям, а также государственные меры, направленные на поддержание экономики. Рассматривается судебная практика по делам, связанным с налоговой преступностью.
The main directions of criminal law policy in the sphere of combating tax crimes are analyzed. Judicial statistics on tax crimes, as well as state measures aimed at supporting the economy, are analyzed. Judicial practice in cases related to tax crimes is considered.