bluuebunny/crossref_metadata_2025_split huggingface dataset:
Default In The Agreement For The Results Of Rice
Authors: Saprudin Hasim Mohamad 
Published: August 2023

Abstract: This paper aims to find out and analyze how the default in the production sharing agreement for cultivating rice fields is viewed from the law. No. 2 of 1960 concerning Agricultural Production Sharing Agreements and the factors that influence the occurrence of default in the production sharing agreement for cultivating rice fields in terms of the Act. No. 2 of 1960 concerning Agricultural Production Sharing Agreements in Gorontalo Regency. This type of research is empirical research.The results of the study show that the default in the profit sharing agreement for cultivating rice fields is viewed from the Law. No. 2 of 1960 concerning Agricultural Production Sharing Agreements in Gorontalo Regency are still being finalized by means of customary deliberations involving the village head as a facilitator. Although there are official regulations by the government, namely UU. No. 2 of 1960 concerning Agricultural Production Sharing Agreements which have clearer arrangements, but until now the provisions of the law have not been applied as expected, it can even be said not to apply at all, it's all because of the regulations of the Act. No. 2 of 1960 concerning the Agricultural Production Sharing Agreement concerning the production sharing agreement was felt by the community to be too complicated. Whereas the factors that influence the occurrence of default in the profit sharing agreement for cultivating rice fields are reviewed from the Law. No. 2 of 1960 concerning Agricultural Production Sharing Agreements in Gorontalo Regency is influenced by internal and external factors. Keywords: Wanprestasi, Agreement, Profit Sharing
Settlement of Estate Disputes in Review From a Legal Anthropological Perspective
Authors: Tombili Alim 
Published: August 2023

This study aims to find out how the settlement pattern is used in the division of inheritance property in North Tamaila village and what factors are obstacles at the time of the division of inheritance property. Emperis type of research with a Case approach. result research shows the pattern of dispute resolution through several stages, the first stage which is known as "Mopotihuloo Ahali Lo Wutato"(deliberation between family and heirs) is the first stage of conducting deliberations internally family between the extended family of the parties to the dispute but did not find the result of the agreement, the second stage is carried out, namely mediation, The inhibiting factor in the settlement of inheritance disputes consists of two factors, internal and external factors internal factors include low education, economy, and low religious understanding. Meanwhile, external factors factor in the lack of socialization from the government and counseling by traditional figures related to the system of distribution of inheritance both in the perspective of goGorontaloustomary law, civil law, and Islamic law.
Sanctions for Criminal Trafficking in Persons
Authors: Onggi Febriyana Febiola 
Published: August 2023

The purpose of this research is to know and analyze aboutsanctions for the perpetrators of the Crime of Trafficking in Persons at the Manado District Court. This type of research is normative research. The results of this study include prostitution, physical, sexual exploitation, utilizing one's energy and or abilities by parties who have control to gain benefits both materially and immaterially. In this case the defendant for committing the crime of trafficking in persons was found guilty, even though there was evidence that from the facts revealed in court the idea of sexual exploitation of the victim actually came from the victim herself who wanted to exploit herself. The actions of the defendant who could be blamed for allowing did not prevent the victim from doing this and the defendant complied with the victim's instructions to chat with the michat application on the victim's cellphone by showing the victim's potential customers. This means that the defendant took part in the sexual exploitation of the victim who is still a child.
The Urgency of Regulation of Electric Bikes in Gorontalo City in a Progressive Legal Perspective
Authors: Puluhulawa Mohamad Rusdiyanto U. , Puluhulawa Jufryanto , Swarianata Vifi , Biya Fitriana Nur 
Published: August 2023

The use of electric bicycles is currently becoming a primadonna among the community. The combination of transportation and technology makes it a creative and revolutionary innovation. High public interest and also based on the thought of the movement to save the Earth from carbon emissions has increasingly popularized the use of electric bicycles. The purpose of this study was to determine and analyze the urgency of regulating electric bicycles in Gorontalo City in a progressive legal perspective. The research method used is statute approach and conceptual approach. Electric bicycles have begun to be traded in the Gorontalo Province. Of course, this indicates that Gorontalo Province has good market potential. Nationally, the rules for the use of electric bicycles have indeed been accommodated in the Minister of Transportation Regulation, but their embodiment in regional regulations is still needed considering that Gorontalo Province in general and Gorontalo City in particular certainly have special conditions. which must also be accommodated in a regulation because the facilities and infrastructure as well as local wisdom that live in the community are certainly not at the same level nationally. It is appropriate that the use of electric bicycles as a means of transportation is made a legal umbrella in the regions. Law through the lens of progressiveness must move faster than society itself considering that law is rigid while society is dynamic
Criminal Policy on Destructive Fishing Activities in Serutbar, Indonesia
Authors: Lewerissa Yanti Amelia , Hehanussa Deassy Antoneta , Adam Sherly 
Published: August 2023

Fishing communities around the North Seram and North West Seran (Serutbar) Marine Protected Areas often carry out destructive fishing activities. This study aimed to examine and analyze criminal policies for destructive fishing activities in the Serutbar Marine Conservation Area. The research method used is normative legal research supplemented by a socio-legal approach. The approach used in this study is a statutory approach and a conceptual approach. The data collection technique is a literature study complemented by field data obtained through observation and in-depth stakeholder interviews. Furthermore, the data were analyzed qualitatively. Based on the research results, Gale-Gale Village and Sawai Village's fishing communities around the Serutbar Waters Conservation Area often carry out destructive fishing activities. The factors that cause them to carry out destructive fishing are economic needs; very simple fishing gear; the provision of assistance needs to be put on target; Pokmaswas being less empowered; and a lack of inter-agency oversight. Meanwhile, countermeasures to overcome destructive fishing can be carried out through penal and non-penal approaches. And a need for inter-agency oversight. Meanwhile, countermeasures to overcome destructive fishing can be carried out through penal and non-penal approaches. And a need for inter-agency oversight. Meanwhile, countermeasures to overcome destructive fishing can be carried out through penal and non-penal approaches.
Intelligent prediction of lower extremity loadings during badminton lunge footwork in a lab-simulated court
Authors: Yu Lin , Jiang Hanhui , Mei Qichang , Mohamad Nur Ikhwan , Fernandez Justin , Gu Yaodong 
Published: August 2023

Introduction: Playing badminton has been reported with extensive health benefits, while main injuries were documented in the lower extremity. This study was aimed to investigate and predict the knee- and ankle-joint loadings of athletes who play badminton, with “gold standard” facilities. The axial impact acceleration from wearables would be used to predict joint moments and contact forces during sub-maximal and maximal lunge footwork.Methods: A total of 25 badminton athletes participated in this study, following a previously established protocol of motion capture and musculoskeletal modelling techniques with the integration of a wearable inertial magnetic unit (IMU). We developed a principal component analysis (PCA) statistical model to extract features in the loading parameters and a multivariate partial least square regression (PLSR) machine learning model to correlate easily collected variables, such as the stance time, approaching velocity, and peak accelerations, with knee and ankle loading parameters (moments and contact forces).Results: The key variances of joint loadings were observed from statistical principal component analysis modelling. The promising accuracy of the partial least square regression model using input parameters was observed with a prediction accuracy of 94.52%, while further sensitivity analysis found a single variable from the ankle inertial magnetic unit that could predict an acceptable range (93%) of patterns and magnitudes of the knee and ankle loadings.Conclusion: The attachment of this single inertial magnetic unit sensor could be used to record and predict loading accumulation and distribution, and placement would exhibit less influence on the motions of the lower extremity. The intelligent prediction of loading patterns and accumulation could be integrated to design training and competition schemes in badminton or other court sports in a scientific manner, thus preventing fatigue, reducing loading-accumulation-related injury, and maximizing athletic performance.
Skill-based differences in the impact of opponent exposure during anticipation: the role of context-environment dependency
Authors: Gredin N. Viktor , Thomas Joseph L. , Broadbent David P. , Fawver Bradley , Williams A. Mark 
Published: August 2023

IntroductionWe examined skilled-based differences in the impact of exposure to an opponent with action tendencies that were either independent of, dependent on, or both independent of and dependent on evolving environmental information during anticipation.MethodsA video-based two-vs.-two soccer task was employed, where 14 expert and 14 novice soccer players had to predict an attacking opponent's imminent actions, before and after exposure to the preceding actions of the opponent.ResultsAnticipation accuracy, number of responses congruent with the opponent's action tendencies, response confidence, and visual dwell time on the opponent in possession increased following opponent exposure, both in experts and novices. When compared to novices, experts demonstrated higher anticipation accuracy, more congruent responses, and greater response confidence. Novices performed at their best when the opponent exhibited action tendencies that were independent of the environment, whereas experts demonstrated their highest performance when the opponent had action tendencies that were both independent of and dependent on unfolding environmental information.DiscussionOur findings provide novel insights into the role of context-environment dependency and support the notion that experts are superior to novices in detecting and utilizing opponents' action tendencies and integrating this information with unfolding environmental information during anticipation.
Bioprosthetic valve thrombosis after transcatheter aortic valve replacement and pulmonary embolism due to heparin-induced thrombocytopenia: a case report
Authors: Faucher Loïc , Marchandot Benjamin , Carmona Adrien , Ohana Mickael , Trimaille Antonin , Morel Olivier 
Published: August 2023

BackgroundBioprosthetic valve thrombosis is a complication of transcatheter aortic valve replacement (TAVR). It is believed to be platelet independent, mainly driven by contact phase activation, and more likely to be targeted by oral anticoagulant (OAC).Case summaryWe report case of an 86-year-old man with history of TAVR, who presented an early TAVR aortic valve thrombosis occurring in the context of heparin-induced thrombocytopenia (HIT) and pulmonary embolism. The patient rapidly recovered and was discharged 17 days after readmission. OAC by Coumadin was administered for 3 months. Chest tomography after 3 months showed the disappearance of the hypoattenuated leaflet thickening.DiscussionAlthough HIT has been fully described and is known for being a prothrombotic disorder, this is the first case report of aortic valve thrombosis after TAVR due to HIT. HIT is rare but possibly lethal. Diagnosis is based on pre-test probability evaluation with the 4T clinical score and confirmation with laboratory evidence of anti-PF4/heparin complexes and positivity of a functional test. Management of HIT is based on heparin discontinuation, and treatment of thrombotic complication with direct anti-IIa inhibitor or anti-Xa inhibitor. According to our knowledge, this case represents the first report of bioprosthetic valve thrombosis after TAVR due to HIT.
Acute pulmonary embolism with arrhythmia associated with minimal change disease in adults: a case report
Authors: Rong Chunyan , Liu Xuhan , Wang Baoguo , Zhang Weihua 
Published: August 2023

BackgroundMinimal change disease (MCD) is a common pathological type of nephrotic syndrome (NS), and is one of the most common causes of NS in children, but is not common in adults. MCD is sensitive to corticosteroid therapy and has a good prognosis, but is prone to relapse. Venous thromboembolism (VTE) is less common in MCD.Case presentationWe report a case of acute pulmonary embolism (PE) with arrhythmia associated with MCD in adults. The hypercoagulable state caused by MCD through multiple systems may be one of the important causes of thrombosis in this patient. In addition to the conventional corticosteroid therapy, he was started on anticoagulation for VTE and PE. His hospital course was complicated by atrial tachyarrhythmias initially controlled by amiodarone but he required readmission due to recurrent atrial flutter. His clinical condition became more stable after radiofrequency ablation.ConclusionVTE associated with MCD in adults is rare. Treatment of MCD with corticosteroids may be associated with a higher risk of developing blood clots. This type of case is relatively rare and should be paid attention to. The mechanism of VTE in MCD is still a direction worthy of further research.
Association between weight-adjusted-waist index and female infertility: a population-based study
Authors: Wen Zujun , Li Xiang 
Published: August 2023

AimsObesity is detrimental to infertility. The association between weight-adjusted-waist index (WWI, a recently developed adiposity indicator) and infertility has not previously been confirmed.MethodsThe data for this study were obtained from the National Health and Nutrition Examination Survey (NHANES) 2013-2018. Each participant’s WWI was calculated as their waist circumference in centimeters by the square root of weight in kilograms. Multivariable logistic regression and generalized additive model were utilized to investigate the relationship between WWI with infertility. We used smoothed curve fitting to explore the non-linear relationship. Subgroup analysis and interaction tests were also conducted.ResultsA total of 3,526 participants with ages from18 to 45 were enrolled, 364 of whom were infertile. With the higher WWI, infertility was more prevalent (OR = 1.42, 95% CI: 1.22-1.65), and this association was still consistent in subgroups (all P for interaction&gt; 0.05). Smoothed curve fitting showed a positive non-linear relationship between WWI and infertility. Furthermore, we discovered that WWI had a stronger connection with the risk of infertility than other markers of obesity including WC, body mass index (BMI) and a body shape index (ABSI).ConclusionsWeight-adjusted-waist index levels were positively linked to an increased risk of infertility in American females and showed a stronger association than other markers of obesity. Our research indicated WWI could help identify women with infertility, and managing obesity as determined by WWI may help to reduce the risk of infertility.
Evaluation method for reservoir damage of cementing slurry
Authors: Li Ji , Wu Dapeng , Zhang Ran , Li Chenguang , Zou Qiang 
Published: August 2023

The damage of cement slurry to the reservoir is directly related to the production of oil and gas wells, and is a problem that must be solved for the efficient and economic development of oil and gas reservoirs. According to the characteristics and field conditions of reservoir damage caused by cement slurry, this paper analyzes the main factors affecting the degree of reservoir damage, puts forward the technical index requirements of the evaluation device, and establishes the evaluation method of reservoir damage caused by cement slurry in case of loss of injection. The results show that the influence of temperature on the damage of the cement slurry layer is small, and the influence of pressure difference on the damage to the cement slurry layer is large; When the pressure difference is 22 Mpa, the penetration damage rate caused by cement slurry to the pore center without mud cake attachment is about 43%. After a day of core maintenance, the permeability damage rate will reach 61.2%; The damage of cement slurry to the pore micro-fractured core is very serious. After 1 day of maintenance, the damage to the core permeability after cement slurry solidification is as high as 83%, with an average of 76.5%; When the risk of leakage is low, the cement slurry system with low density and low water loss can be used for cementing operation. The filtrate of cement slurry should be better matched with the formation clay minerals, formation water, and drilling fluid filtrate. When the risk of leakage is high, high-density cement slurry, balanced pressure cementing, pressure control cementing, and other technologies to avoid leakage can be used for cementing operations. When the cementing conditions are more difficult, the cementing slurry system can be used to dissolve the cementing slurry system at a later stage. The research results provide theoretical data support for the study of reducing the damage of cement slurry to the reservoir.
Rituximab at lower dose for neuromyelitis optica spectrum disorder: a multicenter, open-label, self-controlled, prospective follow-up study
Authors: Zhao Daidi , Ren Kaixi , Lu Jiarui , Liu Zhiqin , Li Zunbo , Wu Jun , Xu Zhihao , Wu Songdi , Lei Tao , Ma Chao , Zhao Sijia , Bai Miao , Li Hongzeng , Guo Jun 
Published: August 2023

ObjectiveTo address a novel lower-dose rituximab (RTX) therapy strategy based on our clinical experience and assess its efficacy and safety in neuromyelitis optica spectrum disorder (NMOSD).MethodsA multicenter, open-label, self-controlled, prospective follow-up study. Totally, 108 NMOSD patients were enrolled and a lower-dose RTX strategy was applied including 100 mg weekly for 3 weeks and then reinfusions every 6 months. Annualized relapse rate (ARR), the expanded disability status scale (EDSS) score and length of spinal cord lesions were included to evaluate the efficacy. Side effects were recorded to assess the safety profile.ResultsOf 108 patients, 80 (74.1%) initiated low-dose RTX therapy immediately after acute attack treatment and 33 (30.6%) initiated it after the first attack. During a median treatment period of 35.5 (22.0–48.8) months, significant decreases were observed in median ARR (1.1 [0.8–2.0] versus 0 [0–0.2], p &lt; 0.001), EDSS score (3.5 [2.5–4.0] versus 2.0 [1.0–3.0], p &lt; 0.001) and spinal cord lesion segments (5.0 [4.0–8.0] versus 3.0 [1.0–6.0], p &lt; 0.001). The cumulative risk of relapses significantly decreased during the post- versus pre-RTX period (HR 0.238, 95%CI 0.160–0.356, p &lt; 0.001) and on early therapy initiated within 24 months after disease onset versus delayed therapy (HR 0.506, 95%CI 0.258–0.994, p = 0.041). No serious side effects were recorded and all the subjects did not discontinue treatment due to RTX-related side effects.ConclusionOur research provided evidence supporting the lower-dose RTX strategy in treating NMOSD and reopened the issues of optimal dosage and therapy initiation timing.
The benefit and risk of PD-1/PD-L1 inhibitors plus anti-angiogenic agents as second or later-line treatment for patients with advanced non-small-cell lung cancer: a systematic review and single-arm meta-analysis of prospective clinical trials
Authors: Chen Shubin , Mo Wanying , Jiang Wei , Zhou Shaozhang , Gan Haijie , Yu Qitao 
Published: August 2023

BackgroundPrevious studies revealed that Programmed cell death protein 1 (PD-1)/Programmed cell death-Ligand protein 1 (PD-L1) inhibitors plus anti-angiogenic agents had extensive anti-tumor activities. However, almost all studies on the efficacy and safety of PD-1/PD-L1 inhibitors plus anti-angiogenic agents as second or later-line treatment for patients with advanced non-small cell lung cancer are non-randomized controlled trials with small sample sizes, which might lead to a lack of effective metrics to assess the effectiveness and safety of the therapeutic regimen. Here, this meta-analysis aimed to evaluate the efficacy and safety of PD-1/PD-L1 inhibitors plus anti-angiogenic agents as second or later-line treatment for patients with advanced non-small cell lung cancerMethodsA single-arm meta-analysis was performed, and published literature from PubMed, Web of Science and Embase databases as of January 13, 2023, was systematically retrieved. We used the Cochrane risk of bias tool and methodological index for non-randomized studies (MINORS) Methodological items to evaluate the quality of eligible clinical trials. Outcomes including overall response rate (ORR), disease control rate (DCR), progression-free survival (PFS), overall survival (OS), and adverse events (AEs) were extracted for further analysis. The random effect model is used to calculate the pooled parameters.Results19 studies (16 were non-comparative single-arm clinical trials and 3 were randomized controlled trials) were enrolled in this meta-analysis. In terms of tumor response, the pooled ORR and DCR were 22.4% (95% CI, 16.6-28.1%) and 76.8% (95% CI, 72.6-81.1%), respectively. With regard to survival analysis, the pooled PFS and OS were 5.20 (95% CI, 4.46-5.93) months and 14.09 (95% CI, 13.20-14.97) months, respectively. The pooled grade ≥3 adverse effect (AE) rate was 47.6% (95% CI, 33.1-62.0%)ConclusionPD-1/PD-L1 inhibitors plus anti-angiogenic agents has promising efficacy and safety as second or later-line treatment in patients with advanced non-small cell lung cancer.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD42023407559.