bluuebunny/crossref_metadata_2025_split huggingface dataset:
Historicizing the Miraculous: Muslim Traditionalism and Colonial Modernity
Authors: Tareen SherAli 
Published: August 2023

Abstract
The text introduced and translated below represents a fragment from the narration and proceedings of an interreligious polemical festival known as “The Festival of Deciding (or Recognizing) the (True) God” (Melah-e Ḳhudā-shināsī) that was held for two consecutive years in 1875 and 1876 in the village of Chandāpūr in the Shāhjahānpūr district of the United Provinces (UP). More specifically, the translation below presents the discourses of the leading Muslim scholar who participated at this event also featuring major Hindu scholars and Christian missionaries, Muḥammad Qāsim Nānautvī (d. 1877), one of the founders of the prestigious Islamic seminary the Deoband Madrasa, on the questions of prophetic miracles and the normative status of Hindu avatars in Islam. Nānautvī’s discourse on these issues showcases an excellent example of the confluence of Muslim traditionalism and resoundingly modern logics of religion and history.
Digital Transformation
Authors: Cöster Mathias , Danielson Mats , Ekenberg Love , Gullberg Cecilia , Titlestad Gard , Westelius Alf , Wettergren Gunnar 
Published: August 2023

Whilst digitisation is far from a new concept, many assume that simply introducing automation and information systems in various forms will be enough to make their organisation’s operations more efficient. This misconception can often lead to disarray and costly mistakes. Digital Transformation: Understanding Business Goals, Risks, Processes, and Decisions shows how to avoid such issues via careful consideration of what an enterprise really needs.
Unlike many other books on digital transformation, the authors do not dwell on database design or the details of implementing information systems. Instead, they emphasise the importance of a clear understanding of all aspects of an organisation in order to effectively implement and manage digital systems, from business goals and strategies to structuring information and making decisions, risk assessments, project management, organising, and procuring services and products.
Organised in eleven chapters, and drawing on examples from all over the world, this book will be of interest to university students of business administration, management, information systems, and computer science, as well as practitioners seeking to better understand how to handle digital transformation in their own organisation.
Analytical assays and bootstrap resampling method to validate performance of the Roche Elecsys STAT highly sensitive troponin T assay and its application for the ‘rule-out’ part of ESC guidelines for NTSTEMI
Authors: Metsu David , Mille Daphné , Pailly Carole , Oancea Valerica G. , Essemilaire Luc , Coppin Dominique 
Published: August 2023

Background The European Society of Cardiology (ESC) guidelines recommend a dynamic (0-1h) cardiac troponin (cTn) determination for non-ST elevation myocardial infarction diagnosis. For patients with low cTn levels, a discharge from emergency can be considered. Nevertheless, cTn cutoffs for discharge are lower than the limits of quantification proposed by laboratory reagent suppliers. Aim Validate cTn assay on the Elecsys STAT kit. Materials and methods Precision, trueness, repeatability and within-laboratory variability were calculated from internal quality control and plasma pooled at 5.78 and 10.73 ng/L. Accuracy was calculated from external quality control. Uncertainty of measurement was calculated from (i) the uncertainty of the standard and control values and (ii) by precision from pooled plasma. Distribution of precision results from pooled plasma has been evaluated by bootstrap simulations. Dilution linearity tests with patient plasma were performed to evaluate the method for values near 5 ng/L. Results Precision and trueness ranged from 1.35 to 4.45% and from 0.14 to −3.74%, respectively. Accuracy results ranged from 101.40 to 104.90%. Within laboratory variability was 2.91%. Uncertainty ranged from 3.66% to 19.90% for higher (2188) to lower values (5.78 ng/L). Bootstrap simulations allowed utilization of precision data from pooled plasma to evaluate cTn assay. The method was linear from 4.48 to 39.80 ng/L. A linear regression model best described the data. Conclusion Elecsys STAT method provides accurate cTn results, including patients with cTn results categorizing them as ‘rule-out’ in the ESC guidelines.
Development of blood collection tubes for glucose measurement using adenosine 3-phosphate and sodium fluoride as glycolytic inhibitors
Authors: Kume Yukio , Hirowatari Yuji , Kurano Makoto , Yatomi Yutaka , Matsushita Makoto 
Published: August 2023

Background Blood collection tubes with sodium fluoride (NaF) added as a glycolytic inhibitor are widely used for glucose measurement. However, the glycolytic inhibitory effects of NaF are insufficient, and decreases in glucose levels over time after blood collection have become a problem. Methods Blood from a volunteer collected using an NaF tube was used to compare the glycolysis inhibitory abilities of ATP and ADP. Blood samples from 10 volunteers were collected in NaF tubes and NaF tubes with added ATP (NaF–ATP tubes). The stability of glucose and haemoglobin (Hb)A1c after whole-blood storage from immediately after blood collection to 24 h later was compared. Results ATP and ADP had similar inhibitory effects on glycolysis, but ATP was selected as an additive for blood collection tubes because ADP was more haemolytic than ATP. We verified the ability of NaF blood collection tubes supplemented with ATP to inhibit glycolysis. Mean (± standard deviation) glucose levels (n=10) after storage for 24 h after blood collection decreased to −9.0 ± 2.7 mg/dL (−0.50 ± 0.15 mmol/L) in conventional NaF tubes. NaF–ATP(20) tubes with 20 mg (0.036 mmol) ATP added showed a reduced decrease, with a mean of −5.8 ± 2.9 mg/dL (−0.32 ± 0.16 mmol/L). NaF–ATP tubes also had no effect on HbA1c measurement. Conclusion This study reports on a blood collection tube that enables the measurement of glucose and HbA1c. Based on the results of validation, we conclude that NaF–ATP tubes can reduce decreases in glucose over time in stored whole blood compared to conventional NaF tubes.
Quetiapine Twice Daily Versus Bedtime Dosing in the Treatment of ICU Delirium
Authors: Hawthorne Ashley , Delgado Elina , Battle Anna , Norton Cory 
Published: August 2023

Background: Although guidelines recommend twice daily (BID) dosing of quetiapine for treatment of intensive care unit (ICU) delirium in most patients, once daily dosing at bedtime (HS) is commonly prescribed to reduce daytime somnolence. No studies have evaluated differences in outcomes. Objectives: To determine if twice daily vs bedtime dosing of quetiapine reduces the duration of ICU delirium. Methods: Retrospective analysis of ICU patients treated with twice daily vs bedtime dosing of quetiapine for ICU delirium. Health records were analyzed between January 1, 2017, and December 31, 2021. Exclusions included alcohol withdrawal, history of psychiatric conditions requiring medication, receipt of <24 hours of therapy, alternative dosing schedules, and death or transfer from the ICU <24 hours after beginning quetiapine. The primary outcome was recovery of delirium per Confusion Assessment Method (CAM-ICU). Secondary outcomes included lengths of stay, mechanical ventilation duration, in-hospital death, and QTc prolongation. Results: Baseline characteristics differed for sex (30.4% vs 61.1% female) and admission diagnosis (39% vs. 17% COVID-19, respectively). Time to delirium recovery was 3.5 days for BID vs 2.5 days for QHS dosing ( P = .484). Secondary outcomes of ICU (16 vs. 19 days) and hospital (22 vs. 25 days) lengths of stay, duration of mechanical ventilation (10 vs. 14), delirium recovery (70% vs. 56%), in-hospital death (61% vs. 50%), and QTc prolongation did not differ significantly between groups. Conclusions: Twice daily vs bedtime dosing of quetiapine did not significantly alter delirium outcomes, suggesting similar efficacy. Larger sample sizes are needed to confirm these results.
Optimising recruitment to a lung cancer screening trial: A comparison of general practitioner and community-based recruitment
Authors: Scobie Hannah , Robb Kathryn A , Macdonald Sara , Harrow Stephen , Sullivan Frank ,   in collaboration with the ECLS study team
Published: August 2023

Objectives Pre-trial focus groups of the Early detection of Cancer of the Lung Scotland (ECLS) trial indicated that those at high risk of lung cancer are more likely to engage with community-based recruitment methods. The current study aimed to understand if general practitioner (GP) and community-based recruitment might attract different groups of people, and to quantitatively explore the demographic and psychosocial differences between people responding to GP or community-based recruitment. Design Secondary data analysis of ECLS trial baseline data. Methods Adults (n = 11,164) aged 50 to 75 years completed a baseline questionnaire as part of their participation in the ECLS trial. The questionnaire assessed smoking behaviour, health state, health anxiety and illness perception. Alongside demographic characteristics, how participants were made aware of the study/participant recruitment method (GP recruitment/community recruitment) was also obtained via trial records. Results The likelihood of being recruited via community-based methods increased as deprivation level decreased. Those recruited via the community had higher levels of perceived personal control of developing lung cancer and were more likely to understand their own risk of developing lung cancer, compared to those who were recruited to the trial via their GP. Health state and health anxiety did not predict recruitment methods in multivariable analysis. Conclusions Community and opportunistic screening invitations were associated with uptake in people from less-deprived backgrounds, and therefore might not be the optimal method to reach those at high risk of lung cancer and living in more deprived areas.
Fixed-point excitation prediction method for environmental vibration of urban rail transit
Authors: He Zhenxing , Bai Yanbo , Xin Xiantao , Su Cheng , Yu Ziyang 
Published: August 2023

In urban rail transit construction, the empirical prediction equation is generally used to predict the environmental vibration along the line after its operation. It is used as the basis for whether to adopt a vibration-damping track or which vibration-damping track to use. Due to the superposition of complex factors such as geological conditions, differences in vehicles, and their running foundations on the prediction results, the track implementation should be considered at least with a design margin of 3 dB. However, there are still a large number of environmental vibration complaints. Therefore, an ecological vibration prediction method with higher prediction accuracy is proposed. The construction of the track-foundations, such as tunnel, bridge, and roadbed is completed. Before the track system is constructed, a fixed-point excitation load simulating the passage of trains is applied on the track-foundation, and the vibration-sensitive points around the line are directly measured by the actual measurement—environmental vibration prediction evaluation. The fixed-point vibration source function model for simulating train passing is deduced as the excitation load applied to the track-foundation; the fixed-point vibration source foundation finite element model and vehicle-track-foundation coupled dynamic model with the same track-foundation and foundation model have been established. The vibration response of the track-foundation and foundation surface when the train passes through is calculated separately. The results corresponding to different prediction methods of environmental vibration are compared and analyzed. The comparison between the theoretical prediction value of vibration response, the prediction value of the empirical equation, and the measured value shows that the vibration response waveform of the foundation surface is the same as that of the actual train passing under the action of the fixed-point vibration excitation source function. The vibration prediction error is much smaller than the empirical equation predicts the result. It shows that the prediction accuracy of the fixed-point excitation prediction method for environmental vibration is higher than that of the existing practical equation method. Because the fixed-point vibration source device is simple to implement and the ecological vibration field testing method is mature, it is beneficial to the field application of the fixed-point vibration excitation prediction method for urban rail transit environmental vibration.
Safety outcomes of rapid- versus standard-infusion rate oxaliplatin
Authors: Huynh Thao , Crozier Nick , Anselmo Lisa 
Published: August 2023

Purpose The National Comprehensive Cancer Network guidelines state that the oxaliplatin dose of 85 mg/m2 used in various gastrointestinal cancer regimens may be infused over a rapid rate of 85 min instead of the standard time of 120 min. We evaluated the safety outcomes of rapid administration of oxaliplatin compared to standard infusion. Methods We performed a retrospective, cohort study by chart review. Adult patients who received oxaliplatin as part of a FOLFOX, FOLFOXIRI, or FOLRINOX chemotherapy regimen from January 1, 2018, through June 30, 2021, were included. Primary outcomes were the incidence of hypersensitivity reaction (HSR) and treatment modification of oxaliplatin due to adverse drug events. Secondary outcomes included peripheral neuropathy (PN), myelosuppressive signs, and oxaliplatin-related emergency department visit and/or hospital admission. Results A total of 178 patients were included (90 and 88 in the rapid-rate and standard-rate groups, respectively). Rapid-rate oxaliplatin was not associated with increased HSR or difference in toxicity requiring dose reduction, delayed dose, or slowed infusion rate, but was associated with increased rate of permanent discontinuation of oxaliplatin, 7.8% and 1.1% in the rapid-rate group and standard-rate groups, respectively ( p = 0.032). Peripheral neuropathy occurred in 72.2% and 42% of patients in the rapid-rate group and standard-rate groups, respectively (relative risk for PN, 2.09; 95%, CI: 1.43–3.04; p < .001). There were no differences in any other adverse drug event measured. Conclusion Rapid-rate oxaliplatin was associated with minimal treatment modifications; however, there was an increase in PN incidence. A faster rate of oxaliplatin administration may not be worth the increased risk of PN.
Considering Communication Theory in Health Education and Behavior: Applying the Integrated Model of Advice-Giving in Friendship Sex Talks
Authors: Fedd Andre , Samp Jennifer A. 
Published: August 2023

Background Individuals may find it challenging and discomforting to communicate about sex because they may lack the skills and efficacy necessary to communicate their sexual desires. When individuals do have opportunities to have such discussions about sex in open and comfortable settings, they may seek informational support (i.e., advice) from a close friend because of knowledge sharing and past experiences navigating sex-related concerns. Aims This research study used a communication theory-based quantitative analysis to examine how advice givers’ prosocial behaviors influence their advice outcome messages during conversations about sex. Methods A total of 264 participants completed a survey developed based on the Integrated Model of Advice-Giving (IMA). Data were analyzed using structural equation modeling. Results Advice givers reported that their emotional supportive messages elicited better quality advice. Additionally, advice givers indicated that being attentive and understanding to others’ feelings elicited better disclosures about their own sexual experiences. Structural equation modeling results suggested a good model fit for the theoretical model (comparative fit index [CFI] = .939, tucker-lewis fit index [TLI] = .931, root mean square error of approximation [RMSEA] = .056, 90% confidence interval: [.049, .063], and standardized root mean square residual [SRMR] = .082). Conclusions This study highlights the theoretical and pragmatic implications of communication theory in sexual health education interventions.
Mönckeberg's Medial Calcific Sclerosis Makes Traditional Arterial Doppler's Unreliable in High-Risk Patients with Diabetes
Authors: Suludere Mehmet A. , Danesh Sahab K. , Killeen Amanda L. , Crisologo Peter A. , Malone Matthew , Siah Michael C. , Lavery Lawrence A. 
Published: August 2023

Objective To assess Mönckeberg's medial calcific sclerosis (MMCS) severity in patients with a diabetic foot infection. Methods This was an analysis of 2 randomized clinical trials in which we evaluated the treatment of 233 patients admitted to the hospital for moderate and severe foot infections. Arterial calcification was defined as visible radiopaque arteries on foot and ankle radiographs, recorded as the most distal visible artery involved (toes, metatarsals, and ankle/hindfoot). Results Most subjects (57.1%, n = 133) had MMCS, with extension to toes in 79 (59.4%), to metatarsals in 32 (24.1%), and to ankle/hindfoot in 22 patients (16.5%). In 7 patients (5.2%) MMCS was solely seen in dorsalis pedis (DP) artery, in 13 patients (9.8%) in posterior tibialis (PT) artery, and in 113 patients (85.0%) MMCS was seen in both arteries. Only 29.2% ( n = 68) of DP arteries and 34.8% (n = 81) of PT arteries were not compressible by Doppler. DP and PT arteries were not compressible more often in MMCS (DP 34.3% vs 20.4%, P = .02 and PT 43.1% vs 21.4%, P < .01), toe-brachial indices of ≥0.7 were significantly more common in people without MMCS (46.0% vs 67.4%, P < .01). In contrast, there were no differences in skin perfusion pressure measurements (>50 mmHg; 67.7% vs 68.0%, P = .96), waveforms (biphasic/triphasic 83.5% vs 77.0%, P = .22), and pulse volume recording (9.6 ± 3.3 vs 13.7 ± 36.0) between patients with and without MMCS. Conclusion MMCS is common in patients with diabetic foot infections. MMCS is associated with noncompressible arterial Doppler studies and likely interferes with the accuracy of arterial Doppler studies.
Effect of Neurokinin-1 Receptor Knockdown on the Expression of RANTES in Allergic Rhinitis
Authors: Wang Hong , Wu Jing , Zhang Ruxin 
Published: August 2023

Background Neurokinin-1 receptor (NK-1R) and normal T cell expressed and secreted (RANTES) have been shown to play important roles in allergic rhinitis (AR). However, whether the regulating effect of NK-1R in AR is achieved via RANTES remains unknown. Methods In the present study, Sprague-Dawley rats were sensitized and challenged with ovalbumin to make AR models. During the challenge period, the rats were treated intranasally with NK-1R-specific small interfering RNA (siRNA) for NKR group, negative siRNA for NCS group, rats in NSAR group and NS group were given saline. The amount of nasal secretion and the numbers of nose rubs and sneezes were measured in each rat. The levels of NK-1R and RANTES in the nasal mucosal tissues were determined through real-time fluorescence quantitative RT-PCR and immunohistochemical staining. The numbers of eosinophils in the collected nasal lavage fluid (NLF) were counted, and the concentration of RANTES in NLF was determined by enzyme-linked immunosorbent assay. Results Compared with that in the NS group, the expression of NK-1R and RANTES was significantly higher in the nasal mucosa of NSAR and NCS group rats. The sneezing and nose rubbing counts and the amount of nasal secretions were increased significantly in the NSAR and NCS groups. Rats in the NKR group experienced greater relief from AR symptoms than rats in the NSAR and NCS groups. Furthermore, knockdown of NK-1R expression also significantly eliminated RANTES expression and eosinophil infiltration in the nasal mucosa of NKR group rats. Conculsion For the first time, we show that intranasal treatment with NK-1R-specific siRNA can significantly decrease RANTES expression, AR-related symptoms, and eosinophil inflammation, suggesting that the regulating effect of NK-1R in the development of AR occurs via alteration of RANTES expression.
The challenges of telephone consultation program during severe acute respiratory syndrome-coronavirus-2 epidemic in Iran: A qualitative study
Authors: Moghri Javad , Kokabisaghi Fatemeh , Tabatabaee Seyed Saeid , Niroumand Sadabad Hasan 
Published: August 2023

Introduction With the spread of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) disease and its potential risks for vulnerable groups such as the elderly with chronic diseases, telehealth appointments gained more attention around the world. However, using such a system brought about challenges to patients and service providers that need to be addressed by policymakers for system improvement. Purpose The present study was conducted with the aim of investigating the challenges of the telephone consultation program, which was run by the Social Security Insurance Organization of Iran during the epidemic of SARS-CoV-2. Methods This qualitative study was conducted through semi-structured interviews with physicians who participated in the program, using a purposive sampling approach. The interviews were recorded, transcribed verbatim, and analyzed through conventional content analysis by ATLAS.ti9 software. Findings Based on the results of the qualitative content analysis, the challenges in three categories, including program development, implementation, and evaluation and monitoring, and with 10 themes (planning challenges, infrastructure provision, education and culture building, legal issues, motivational mechanisms, effective communication, efficiency, and effectiveness of care, organization, monitoring, and evaluation) and 26 sub-themes were extracted. Conclusion Telephone appointments allow medical centers to serve some patients better. However, properly implementing the telephone consultation program requires better planning, training, appropriate infrastructure, and continuous evaluation and improvement of processes.