bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kidins220 sets the threshold for survival of neural stem cells and progenitors to sustain adult neurogenesis
Authors: Puerto Ana del , Martí-Prado Beatriz , Barrios-Muñoz Ana L. , López-Fonseca Coral , Pose-Utrilla Julia , Alcover-Sanchez Berta , Cesca Fabrizia , Schiavo Giampietro , Campanero Miguel R , Fariñas Isabel , Iglesias Teresa , Porlan Eva 
Published: January 2023

ABSTRACTIn the adult mammalian brain, neural stem cells (NSCs) located in highly restricted niches sustain the generation of new neurons that integrate into existing circuits. A reduction in adult neurogenesis is linked to ageing and neurodegeneration, whereas dysregulation of proliferation and survival of NSCs have been hypothesized to be at the origin of glioma. Thus, unravelling the molecular underpinnings of the regulated activation that NSCs must undergo to proliferate and generate new progeny is of considerable relevance. current research has identified cues promoting or restraining NSCs activation. Yet, whether NSCs depend on external signals to survive or if intrinsic factors establish a threshold for sustaining their viability remains elusive, even if this knowledge could involve potential for devising novel therapeutic strategies. Kidins220 (Kinase D-interacting substrate of 220 kDa) is an essential effector of crucial pathways for neuronal survival and differentiation. It is dramatically altered in cancer and in neurological and neurodegenerative disorders, emerging as a regulatory molecule with important functions in human disease. Herein, we discover severe neurogenic deficits and hippocampal-based spatial memory defects in Kidins220 deficient mice. Mechanistically, we demonstrate that Kidins220-dependent activation of AKT in response to EGF restraints GSK3 activity preventing NSCs apoptosis. Hence, Kidins220 levels set a molecular threshold for survival in response to mitogens, allowing adult NSCs to proliferate. Our study identifies Kidins220 as a key player for sensing the availability of growth factors to sustain adult neurogenesis, uncovering a molecular link that may help paving the way towards neurorepair.
Regularization regression methods for aerodynamic parameter estimation from flight data
Authors: Kumar Ajit , Ghosh A.K. 
Published: January 2023

PurposeThe purpose of this study is to estimate aerodynamic parameters using regularized regression-based methods.Design/methodology/approachRegularized regression methods used are LASSO, ridge and elastic net.FindingsA viable option of aerodynamic parameter estimation from regularized regression-based methods is found.Practical implicationsEfficacy of the methods is examined on flight test data.Originality/valueThis study provides regularized regression-based methods for aerodynamic parameter estimation from the flight test data.
How cultural intelligence affects expatriate effectiveness in international construction projects
Authors: Chen Yuan , Yang Ziyue , Liu Bingsheng , Wang Dan , Xiao Yan , Wang Anmin 
Published: January 2023

PurposeThis study aims to investigate the influence mechanism of expatriates' cultural intelligence (CQ) on expatriate effectiveness (task performance and premature return intention), identifying work engagement as a mediator and cultural distance as a boundary condition.Design/methodology/approachDrawing on the conservation of resource theory and the person–environment fit (P–E fit) theory, a moderated mediation model is built. Working with a sample of 303 international construction expatriates collected by snowball sampling, the hypotheses are tested by using the structural equation model analysis.FindingsWork engagement partially mediates the relationship between expatriates' CQ and task performance, as well as fully mediates the relationship between expatriates' CQ and premature return intention. Cultural distance moderates the positive relationship between CQ and work engagement, as well as moderates the mediating effects of work engagement.Research limitations/implicationsThe impacts of potential moderators (e.g. work–family conflict and organizational culture) on the relationship between CQ and expatriate effectiveness have not been considered in this study.Practical implicationsThis study is useful for international construction firms to optimize the allocation of human resources.Originality/valueThis study contributes to the expatriate literature by adding empirical evidence to explain the influence mechanism of expatriates' CQ on expatriate effectiveness.
Modeling users’ and practitioners’ intention for continued usage of the Internet of Medical Devices (IoMD): an empirical investigation
Authors: Singh Manpreet , Tandon Urvashi , Mittal Amit 
Published: January 2023

Purpose
The purpose of this paper is to identify the antecedents of continued usage intentions in the connected devices ecosystem in health care by analyzing the users' and physicians' expectations in a new ecosystem where one prefers to connect digitally rather than physically.

Design/methodology/approach
This is a unique study in which data was collected from 242 doctors and 215 end-users to gauge the expectations from the connected devices in health care. Further, these responses were hypothesised using UTAUT-2 and ECT theories to analyze general users’ and professional users’ or doctors’ expectations for continued usage in connected devices ecosystem in the health-care ecosystem.

Findings
Performance expectancy, social influence, facilitating conditions and price value emerged as significant predictors of satisfaction in both user groups. But habit and hedonic motivation reflected an insignificant impact on user satisfaction. Surprisingly, effort expectancy emerged as a significant factor for end-user satisfaction, and this became insignificant for professional user satisfaction. Satisfaction was positively related to continued usage for both user groups, and app quality has a positive impact on all the predictors.

Practical implications
To the best of the authors’ knowledge, this is the first comparative study to understand the factors which influence consumer behavior leading to a holistic model and can be imbibed for creating a better customer experience in an era where we are more comfortable connecting digitally rather than physically.

Originality/value
This study has used the Unified Theory of Acceptance and Use of Technology-2 model and expectation confirmation theory to analyze the key factors influencing the intentions for continued usage of devices in the Internet of Medical Devices setup.
Factors influencing international students' trajectories: a comparative study of Chinese students in Japan and Australia
Authors: Liu Tongrui , Sato Yuriko , Breaden Jeremy 
Published: January 2023

PurposeThis study aims to compare Chinese students' educational and career trajectories in Japan and Australia and to explore the factors that have influenced their choices that shaped their trajectories.Design/methodology/approachThe authors applied the push-pull and life planning models to compare the factors that shaped the Chinese students' trajectories in Japan and Australia. The mixed-method approach was adopted by combining the result of 353 questionnaire responses and ten semi-structured interviews of Chinese international graduates to understand the factors influencing their decision-makings when choosing a study destination, a workplace and a place for settlement. The authors also interviewed six human resources managers of local companies to understand how Chinese international graduates are evaluated in the host country's labor market.FindingsWhen choosing a study destination, cultural interest and inexpensive tuition fees are the pull factors for Japan, while family and friends' recommendations are strong motivations in choosing Australia. After graduation, utilization of capacity/specialty is a pull factor to work in Japan, while the prospect of promotion, good living environment and consideration for spouse/parents/children are the pull factors for Australia. Chinese graduates in Australia have stronger aspiration to remain in their study destination.Originality/valueSince there are few cross-national studies on international students' trajectories, this study filled the research gap by comparing the trajectories of Chinese students in Japan and Australia and clarifying the factors that shaped them.
Impact of social media distraction on student evaluation of teacher effectiveness
Authors: Nema Priyanka , Srivastava Ritu , Bhalla Rohan , Chakarboty Abhinandan 
Published: January 2023

PurposeThe study examines the impact of social media distraction on the relationship between student engagement and student evaluations of teachers (SET) in management education, part of the STEM disciplines. While it is widely accepted that student engagement and evaluation of teachers are two important constructs of active learning systems, their links, especially in the context of management education, have not been explored. This study seeks to fill this research gap as teachers' appraisal and career growth greatly depend on SET across higher education institutes worldwide.Design/methodology/approachData were collected from 247 student participants from higher education institutes/universities using a questionnaire-based survey. Further, 15 students were interviewed to glean insights from their feelings regarding social media distractions and how it impacts their engagement and evaluation of teachers. For the quantitative and qualitative analyses, multiple regression and thematic analysis were applied, respectively. A word tree was developed to determine the association between experiences and contexts.FindingsThe results indicate that social media distraction moderates the relationship between students' cognitive engagement and their evaluation of teaching faculty. Social media distractions disrupt student engagement inside the classroom, leading to wrong/biased assessments of teachers' performance. Additionally, cognitive and emotional engagement significantly impacted student evaluations of the management college faculty.Originality/valueThe authors’ findings enable educators in higher education systems, specifically management education, to rethink the faculty feedback system and social media distractions impeding student engagement other than SET drawbacks.
The influences of expressive and instrumental social ties in social commerce: integrating dyadic views from buyers and sellers
Authors: Li Xixi , Li Zhijie , Wang Qian , Guo Xunhua 
Published: January 2023

PurposeEntrepreneurs and individual sellers heavily leverage their social ties embedded in social media, expressive or instrumental, to penetrate the market and achieve business success. However, the extant social commerce literature offers limited understanding on how different forms of buyer−seller social ties embedded in social media affect buyers' purchase behaviors. The study draws on the theoretical lens of social ties and proposes an integrative theoretical framework to understand the direct and indirect influences of expressive and instrumental ties (ExTSM and InTSM) between buyers and sellers on buyers' purchase intention (PI) in social commerce.Design/methodology/approachThe authors first validated the measures of ExTSM and InTSM with survey data from 166 Weibo commerce buyers. They then tested their theoretical framework and hypotheses with survey data from 246 buyer−seller dyads in WeChat commerce.FindingsWith a buyer-centric view, (1) ExTSM and InTSM, respectively, had a direct negative and a positive influence on PI; (2) both trust and perceived product value displayed inconsistent mediation effects on the negative relationship between ExTSM and PI; and (3) only perceived product value mediated the positive influence of InTSM on PI. From sellers' viewpoint, (1) their ExTSM and InTSM with buyers were mixed up, and (2) the mingled social ties negatively impacted buyers' purchase intention.Originality/valueThe findings of the study advance the theoretical understanding of social commerce and offer practical guidance for small and medium-sized enterprises to effectively utilize social media for business purposes.
Customer satisfaction as a mediator of service facility and word of mouth in higher learning institutions
Authors: Kazungu Isaac , Kubenea Hadija 
Published: January 2023

PurposeHigher learning institutions (HLIs) need to have quality service facilities to achieve customer satisfaction and positive word of mouth (WoM). The purpose of this study is to assess customer satisfaction as a mediator of service facility and WoM in the context of Tanzania's HLIs.Design/methodology/approachA mixed-methods approach was used to achieve the study objectives. Stratified and simple random sampling techniques were adopted to obtain the names of 201 students in HLIs in Tanzania. Confirmatory factor analysis (CFA) and structural equation modelling (SEM) were used to test the hypotheses.FindingsThe findings show that service facility is significantly associated with both WoM and customer satisfaction, while the relationship between customer satisfaction and WoM is significant. The study also found that customer satisfaction mediates the relationship between service facility and WoM.Practical implicationsThe practitioners of HLIs can invest in improving service facility. Service quality is an important component that impacts WoM in HLIs. This is the most important element that impacts students' satisfaction and WoM in HLIs more than any other element of service quality.Originality/valueThis paper adds to the body of knowledge on the role of customer satisfaction in mediating the relationship between service facility and WoM in the context of Tanzania's HLIs. This study also presents a methodological contribution for a better understanding of the predictors of customer satisfaction in HLIs from the students' point of view.
The Satoshi laundromat: a review on the money laundering open door of Bitcoin mixers
Authors: See Kenneth 
Published: January 2023

Purpose
The purpose of this paper is to examine the currently known techniques to tackle money laundering in Bitcoin mixers, and examine what gaps exist that would allow a criminal to get away with laundering Bitcoin obtained through illicit activities.

Design/methodology/approach
This paper first establishes the relevant properties of Bitcoin, how transactions occur over the Bitcoin network and then introduces the Bitcoin transaction graph as an important data structure for any analysis of Bitcoin transactions. Next, the paper outlines how Bitcoin mixing works, along with the relevant properties of mixers that would be relevant for money laundering. The paper then assesses the known methods for identifying mixed transactions within the Bitcoin network, followed by an assessment on identifying money laundering activities on known mixed transactions.

Findings
This paper argues that there remains a gap for criminals to launder money through Bitcoin mixing services as known methods would unlikely be able to trace a tainted transaction that goes through a decentralized mixer that uses off-chain communication techniques to coordinate the mixing and charges randomized mixing fees.

Research limitations/implications
The study of known methods is restricted to literature published in the public domain. There are private organizations that are tackling similar problems, but their methods are not published and therefore cannot be included in this paper.

Originality/value
To best of the author’s knowledge, this is the first paper that performs a contemporaneous review on anti-money laundering in the context of Bitcoin mixing. This paper could assist regulators and policymakers in their understanding of Bitcoin mixers and provide guidance on where they should focus their resources to address the money laundering problem of Bitcoin mixing.
Consumer attitudes and purchase intentions towards internet celebrity self-brands: an integrated view of congruence, brand authenticity and internet celebrity involvement
Authors: Tseng Timmy H. , Wang Han-Yu 
Published: January 2023

Purpose
Internet celebrities have become key resources for consumers making purchase decisions. An increasing number of internet celebrities have begun to exert their influence by creating self-branded products. This study aims to examine the antecedents of consumer attitudes and purchase intentions towards internet celebrity self-brands by integrating cognitive consistency theory, cue utilisation theory and the literature on brand authenticity and celebrity involvement.

Design/methodology/approach
Two sub-samples of different social media brand communities were collected via online surveys of consumers with experience purchasing targeted internet celebrity self-brands. Partial least squares structural equation modelling (PLS-SEM) was used to analyse the data.

Findings
The results of the two sub-samples provide convergent evidence that brand–consumer congruence, brand authenticity and internet celebrity involvement have positive correlations with consumer attitudes towards internet celebrity self-brands, which then positively correlate with purchase intentions in both psychological (Sub-sample 1) and social (Sub-sample 2) brand communities.

Originality/value
To the best of the authors’ knowledge, this research is the first to develop a comprehensive model of consumers’ attitudes towards internet celebrity self-brands, which predict purchase intentions. The model is empirically tested in different social media brand communities, and the convergent results show the power of the proposed model. Internet celebrity involvement is proposed as a key driver of brand attitudes, which has received little attention. We conceptualise internet celebrity involvement and develop a scale to measure it. Based on the findings, we propose strategies to improve the marketing effectiveness of internet celebrity self-brands.
Subordinates’ silence: the consequence of bullying behaviour and psychological insecurity among policemen
Authors: Vem Linus Jonathan , Peter Julfa Christian , Tali Danjuma Nimfa , Ochigbo Abel Daniel , Sambasivan Murali , Nmadu Teresa Mwuese 
Published: January 2023

PurposeThere has been a growing concern about employee silence (ES) within an organization. ES is associated with low creativity and innovativeness, unethical organizational practices, avoidable errors and safety-related issues. The purpose of this study is to evaluate the mediating role of psychological insecurity (PI) in the relationship between leaders’ bullying behaviour (LBB) on defensive (DES) and acquiescent employee silence (AES).Design/methodology/approachData were collected among police personnel working in Plateau state Nigeria. In all, a total of 350 responses were found useable for further analysis, of the 398 copies of the questionnaire administered. A structural equation modelling technique was used via SMART-PLS version 3.3.3 to test the hypothesized relationship.FindingsThe findings of this study revealed that leaders’ bullying positively and significantly influences both AES and DES, and PI was found to mediate the relationship between LBB and AES and DES.Originality/valueLBB among the police has been under-researched, even when there is clear evidence of its existence. PI explains the mechanism through which LBB influences officers' silence.
Changes in dietary intake of aspartic acid during and after intermittent fasting correlate with an improvement in fasting glucose in overweight individuals
Authors: Karras Spyridon N. , Koufakis Theocharis , Dimakopoulos Georgios , Popovic Djordje S. , Kotsa Kalliopi 
Published: January 2023

Highlights
We investigated a potential correlation between amino acid intake and glycemic markers among individuals who practiced intermittent fasting and controls.
Reduced aspartic acid intake during and after intermittent fasting presented a positive correlation with fasting glucose.
The positive effects of intermittent fasting on glucose metabolism could be partially related to a decrease in the ingestion of specific amino acids.
Sporadic hypophosphatemic osteomalacia combined with psoriasis: A rare case report and a brief review of the literature
Authors: Li Yuan , Chen Xiaohong , Wang Bin , Liu Xiaoming , Hou Suchun 
Published: January 2023

AbstractBackgroundHypophosphatemic osteomalacia (HO) is an unusual metabolic disease characterized by low concentrations of serum phosphate levels, which leads to reduced mineralization of the bone matrix. Typically, HO consists of 4 common types: X‐linked dominant hypophosphatemia (XLH), autosomal dominant hypophosphatemic rickets (ADHR), tumor‐induced osteomalacia (TIO), and sporadic HO.Case PresentationWe herein report the case of a 48‐year‐old man who developed multiple joint and bone pain and muscle weakness over 5 months with a 23‐year history of psoriasis. He was diagnosed with psoriatic arthritis by primary hospitals but was unresponsive to etanercept and adalimumab treatments. After referral to our hospital, the patient was diagnosed with HOs combined with psoriasis. The patient was treated with oral phosphate solution, calcium, and active vitamin D, and the symptoms of bone and joint pain and muscle weakness gradually relieved. Since TIO accounts for the majority of adult‐onset HO, positron emission tomography – computed tomography or octreotide imaging examinations had been done yearly to locate any underlying tumor in our patient, with negative findings in the 4‐year follow‐up.ConclusionsDiagnosis of HO remains a challenge to rheumatologists, and especially to dermatologists when accompanied by psoriasis. After excluding the inherited HO and with negative tumor, this report may be the first male case of sporadic HO combined with psoriasis.
Social jetlag and body mass index among shift‐working nurses in Korea: A cross‐sectional study
Authors: Hwang Kyu Rim , Lee Miyoung , Jang Sun Joo 
Published: January 2023

AbstractPurposeShift‐working nurses must function against their natural circadian system and are, thus, bound to be detrimentally affected by social jetlag. Circadian rhythms play a crucial role in regulating homeostasis, and social jetlag may increase one's risk for obesity. Therefore, this study aimed to identify associations between social jetlag and obesity among shift‐working nurses.MethodsThis cross‐sectional study included 183 nurses working rotating shifts in South Korea. Chronotype and social jetlag were measured using the Morningness‐Eveningness Questionnaire and the Munich Chronotype Questionnaire for Shift‐Workers, respectively. Obesity was defined as a body mass index of 25.0 or higher, which was calculated using self‐reported height and weight data. The associations between chronotype, social jetlag, and obesity were investigated using multiple logistic regression analysis.FindingsA total of 183 nurses were included in the analysis (81.4% women and 80.3% single, median age = 27.00 years). Majority of the participants’ (95.1%) chronotypes were moderate evening or intermediate type. The mean overall social jetlag was 3 h and 31 min. The odds for obesity were 8.44 times higher among shift‐working nurses whose social jetlag was over 3 h and 31 min (95% confidence interval: 1.66–42.99) while controlling for chronotype, exercise time, and eating habits.ConclusionsSocial jetlag may increase the likelihood of obesity among rotating shift‐working nurses.Implications for Nursing PracticeTo achieve positive outcomes for promoting nurses’ health, upper nursing management should consider individual nurses’ social jetlag when scheduling shifts. In addition, nursing managers should have the responsibility to educate nurses involved in shift work about the adverse effects of social jetlag.