bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengembangan modul geografi berbasis pendekatan saintifik pada materi dinamika hidrosfer
Authors: Sultoni Muhammad , Budijanto Budijanto , Utaya Sugeng 
Published: August 2023

Learning in the 2013 curriculum scientific learning process through 5 activities: observing, asking, gathering information, associating, and communicating. Modules are one of the teaching materials that can help scientific learning. This study aims to develop a geography module based on a scientific approach to the hydrosphere dynamics material. The development procedure adopts the ADDIE model with five stages of analysis, design, and development, implementation, and evaluation. However, the research and development of this module has only reached the development stage due to limited time, effort and cost. The subjects of this study were experts (material, media, and language) to determine the level of module validity and prospective users (teachers and students) to determine the response to the module. Data collection using a validation questionnaire to obtain quantitative data and qualitative data. The results of the research and development of the module are very valid/feasible to use with a score from the material validator of 91.4 percent, 100 percent media, and 100 percent language. Prospective users (teachers and students) respond to the module, which shows the module "very good" with the total score obtained from the teacher is 100 percent and the student is 88.5 percent.
Pembelajaran pada kurikulum 2013 menekankan proses pembelajaran saintifik melalui kegiatan 5M yaitu mengamati, menanya, mengumpulkan informasi, mengasosiasi, dan mengomunikasi. Modul merupakan salah satu bahan ajar yang dapat membantu pembelajaran saintifik. Penelitian ini memiliki tujuan untuk mengembangkan modul geografi berbasis pendekatan saintifik pada materi dinamika hidrosfer. Prosedur pengembangan mengadopsi model ADDIE dengan 5 tahapan analize, design, dan development, implementation, dan evaluation. Namun pada penelitian dan pengembangan modul ini hanya sampai pada tahap develompent dikarenakan keterbatasan waktu, tenaga dan biaya. Subjek penelitian ini adalah ahli (materi, media, dan bahasa) untuk mengetahui tingkat validitas modul, dan calon pengguna (guru dan siswa) untuk mengetahui respon terhadap modul. Pengumpulan data menggunakan angket validasi, untuk memeroleh data kuantitatif dan data kualitatif. Hasil penelitian dan pengembangan modul sangat valid/layak digunakan dengan perolehan skor dari validator materi sebesar 91,4 persen, media 100 persen, bahasa 100 persen. Calon pengguna (guru dan siswa) memberikan respon terhadap modul yang menujukkan modul “sangat baik” dengan jumlah skor yang didapat dari guru sebesar 100 persen dan siswa sebesar 88,5 persen.
Clinical Features and Risk Factors of Relapse and Mortality in Thrombotic Thrombocytopenic Purpura Patients: A Seven-Year Experience
Authors: Shiraji Sahar Tavakoli , Foumani Hosein Kamranzadeh , Mousavi Seied Asadollah , Vaezi Mohammad , Rad Soroush , Babakhani Davood , Barkhordar Maryam , Bahri Tanaz , Janbabaei Ghasem , Malekmohammadi Ashraf , Mohammadi Saeed , Rostami Mohammad Reza , Mansouri Vahid 
Published: August 2023

Background: Thrombotic thrombocytopenic purpura (TTP) is associated with microangiopathic hemolytic anemia, thrombocytopenia, and microvascular thrombosis. No comprehensive report exists on clinical characteristics and risk factors of relapse and mortality in Iranian TTP patients. In this study, we aimed to report clinical features of Iranian TTP patients, to evaluate disease relapse and mortality rate and their associated risk factors.
Materials and Methods: This study was a cohort study of patients diagnosed with microangiopathic hemolytic anemia admitted to the Shariati Hospital, Tehran, a referral center for TTP patients, from 2010 to 2017. Demographic, clinical, and laboratory data were recorded and patients were followed for 3 years regarding disease relapse and mortality.
Results: 114 patients (80 female, 34 male) with a mean age of 39.3 ± 14.99 years were included. Hematologic and neurologic symptoms were the most common manifestations. Abnormal laboratory findings at the presentation included thrombocytopenia, anemia, and elevated LDH. All patients were treated with plasma exchange, and 75.5% of them had a response to treatment, while the 3-year relapse and mortality rate was 23.6 and 26.3%. Lower platelet count was a predictor of disease relapse. Age, hematological, or neurological initial presentation were associated with TTP mortality.
Conclusion: Based on the largest study of TTP patients ever in Iran, the demographic and clinical characteristics of Iranian TTP patients are similar to other existing reports. Knowledge of the risk factors for TTP relapse and mortality could be useful to alert hematologists for prompt therapeutic actions when necessary.
Effect of Organic Nutrient Management Practices on Growth and Yield of Short-duration Cassava (Manihot esculenta Crantz)
Authors: Aravind S. Ashokh , Somasundaram E. , Sanbagavalli S. , Kavitha P.S. , Venkatachalam S.R. , Sunitha R. 
Published: August 2023

Background: Cassava is an important tropical tuber crop with great potential, particularly for short-duration varieties. Understanding the impact of nutrient management practices on the growth and yield of cassava is crucial for improving its productivity. Methods: Field experiments were conducted at Tapioca and Castor Research Station, Yethapur, Salem in 2022-2023 to determine the effect of various nutrient management practices on the growth attributes, biomass production, dry matter distribution and yield characteristics of short-duration cassava. The experiment was laid out in a randomized block design with twelve treatments and three replications. Results: The integrated nutrient management practice of FYM @ 25 t ha-1 + 100% RDF + cassava booster spray (T10) resulted in higher crop growth, dry matter production, yield attributes, tuber yield and top yield. This was comparable with the organic practice of Wood ash @ 2 t ha-1 + 3% panchagavya foliar spray (T7) among other organic practices. The control treatment with no manures, fertilizers or foliar sprays recorded lower growth and yield. The positive correlation between growth and yield attributes and yield was also observed. In conclusion, the application of FYM @ 25 t ha-1 + 100% RDF + cassava booster spray and Wood ash @ 2 t ha-1 + 3% panchagavya foliar spray were effective in improving the growth and yield of short-duration cassava. From the study, it is also evident that the short-duration cassava is suitable for organic cultivation and can be integrated into existing cropping systems.
SCHIZOPHRENIA INFORMAL CAREGIVERS OPTIMISM: THE EFFECTIVENESS OF QURAN RECITATION LISTENING THERAPY
Authors: Nashori Fuad , Azkia Rakhmandari Ratna , Winarni Wahid Abdi , Yunita Setiyani Ratna , Musa Muwaga , Faza Akhnaf Ardhito 
Published: August 2023

Informal caregivers are usually uncertain about the recovery and life expectancy improvement of schizophrenic patients. This study aimed to determine Quran recitation listening therapy's effectiveness in increasing optimism in schizophrenia informal caregivers. Optimism was measured using the Life Orientation Test-Revision (LOT-R) developed by Scheier, Carver, and Bridges. Quran recitation listening therapy was conducted using the tartil method. The Qori’ recited surah Ar-Rahman with and without interpretation for experimental groups 1 and 2 comprising informal caregivers. Furthermore, hypotheses were tested quantitatively with the Wilcoxon analysis technique to determine the effect of the Quran recitation listening therapy on optimism. The results showed that Quran recitation listening therapy with and without interpretation effectively increased informal caregivers' optimism. The finding justified the theory that Islamic religious intervention in the Quran recitation listening therapy with and without interpretation effectively increases optimism
Evaluation of Website Based Information System To Monitor Student Learning Progress In Schools Using ISO/IEC 9126 Standards And GTMetrix
Authors: Mahadika Dhaniaffa Adhimastama , Aristyagama Yusfia Hafid , Budiyanto Cucuk Wawan 
Published: August 2023

This study aims to evaluate website based information systems that have been developed previously using ISO/IEC 9126 Standards and GTMetrix. Testing of website based information systems using ISO/IEC 9126 is carried out by information system expert, users, and testing using GTMetrix, the user referred to in the test these are administrators, teachers, and student parents. Testing of information system experts takes four measures of quality including functionality, reliability, usability, and portability, while testing on users takes three measures including functionality, usability, and portability, and testing using GTMetrix takes a measure of quality efficiency and serves to assess the performance of the website-based information system developed. The results obtained from the evaluation were testing of information system expert getting a score of 91.17%, administrator user getting a score of 95.11%, teacher user getting a score of 91.35%, student parents getting a score of 83.4%, and testing using GTMetrix getting a score of 86.13% or Grade B. Based on the results of the evaluation using ISO/IEC 9126, it was found that the testing using ISO/IEC 9126 for the tested website-based information system has been meet the expectations of users, especially parents and the school.
Studi Penerapan Sky Garden pada Rumah Susun Jatinegara Barat
Authors: Hakim Hakim , Endangsih Tri 
Published: August 2023

Pertambahan penduduk, kemajuan teknologi, dan tren lanjutan menuju migrasi dalam kota melalui kemajuan ekonomi telah mengubah ruang kota tradisional menjadi kota objek modern yang bertingkat tinggi. Hal ini memerlukan solusi spasial dan teknologi alternatif untuk mengisi kembali lingkungan yang dulunya sangat intrinsik untuk warga berinteraksi. Penelitian ini mempertimbangkan sky court dan sky garden dalam hal sosial, manfaat ekonomi, lingkungan dan spasial yang mereka berikan ke habitat perkotaan. Penelitian ini memiliki berpotensi menjadi ruang sosial ‘alternatif’ yang dapat menjadi bagian dari infrastruktur ruang terbuka multi-level yang lebih luas mengisi hilangnya ruang terbuka dalam habitat perkotaan. Penelitian ini bertujuan untuk mengetahui tingkat pemahaman warga terhadap pentingnya tanaman untuk meningkatkan kualitas lingkungan tempat tinggalnya. metode deskriptif kuantitatif untuk dapat mendeskripsikan gambaran dari situasi atau kejadian yang sedang berlangsung secara alami. Hasil penelitian ini menunjukan bahwa sky garden menjadi salah satu alternatif untuk menghijauan lingkungan permukiman. Sky garden dengan tipycal type dengan posisi one edge, terpilih sebagai pilihan utama warga karena mereka merasa lebih familiar dalam perawatannya
Perceptions of Racial and Gender Microaggressions in an Academic Orthopaedic Department
Authors: Carino Mason Marisa R. , Pandya Shivani , Joshi Priyashma , Cai Nathan , Murdock Christopher J. , Hui-Chou Helen G. 
Published: August 2023

Background:
Orthopaedic surgery consistently ranks last among all medical specialties in diversity and inclusion. While active efforts have recently been implemented to enact change, no study to date has explored the potential effects that social microaggressions have on an individual's career in orthopaedic surgery. The primary aim of this study was to investigate the influence of the perceived experiences of gender and race-based microaggressions on orthopaedic surgery residents, fellows, and attendings in their decision to pursue a career in orthopaedic surgery.

Methods:
A 34-question institutional review board–approved, modified version of the validated Racial and Ethnic Minorities Scale and Daily Life Experiences survey was sent to a total of 84 individuals at the University of Miami (UM) Department of Orthopaedics. Responses were anonymously collected from current UM orthopaedic residents, fellows, and attendings. Survey results were analyzed for the prevalence of microaggressions in the context of sex, race, ethnicity, academic goals, daily scenarios, and department support. p-Values less than 0.05 were considered statistically significant.

Results:
Fifty-four of 84 respondents (64%) completed the survey. Female respondents experienced significantly more gender-based microaggressions than male respondents. On average, male participants disagreed that their experiences with microaggressions made them doubt their ability to pursue a career in orthopaedic surgery while female participants responded they were neutral. In comparison with their White counterparts, non-White and Hispanic ethnicity participants demonstrated a statistically significantly greater frequency of race and ethnicity-based microaggressions.

Conclusion:
Our study demonstrates that female participants, non-White participants, and Hispanic minorities across all levels of training experience a higher frequency of microaggressions. The impact of these experiences on career decisions and goals for women and persons of color in orthopaedic surgery at this single institution is mixed. Experienced microaggressions should be further investigated as a potential barrier to recruitment and retention of under-represented minorities in orthopaedic surgery.

Level of Evidence:
III
The Effect of Camshaft Racing on Matic Motorcycle Performance
Authors: Marfizal  , Wardianto Dedi , Jalis Aliska 
Published: August 2023

The research conducted in this paper is related to the Effect of Camshaft Racing on Motor Matic Performance. For Performance Testing such as power, torque, engine speed, acceleration at engine speed of 6000 to 9000 rpm. Performance testing using a dyno test tool type Super Dyno 50L. The results of this test are used to compare the performance of an automatic motorcycle using a standard camshaft (STD) and a Racing camshaft (BRT). From this study it was found that the performance for the Racing camshaft (BRT) increased compared to the standard camshaft performance (STD), the acceleration value was 6.2% to 4.5%, speed 1.0% to 0.6%, power 9.0% to 4.5%. 16.2%, torque 6.1% to 2.9%. In general, it can be said that camshaft Racing (BRT) has better performance.
Association of Heart Rate with Global Left Ventricular Longitudinal Strain and Left Atrium Structural and Functional Changes in Hypertensive Patients with Normal Left Ventricular Ejection Fraction (A Speckle Tracking Study)
Authors: Emre Ender , Özderya Ahmet , Hancı Kaan , Turan Turhan , Tezen Ozan , Kalaycıoğlu Ezgi , Çetin Mustafa 
Published: August 2023

Abstract
Background: The structure and functions of the left heart cavities have important prognostic value in heart diseases and heart rate control is among the important treatment goals.
Objectives: In this study, we investigated the effects of heart rate on left heart structure and functions in hypertension patients with normal left ventricular systolic function.
Methods: This is a single-center, prospective, observational (case-control) study. One hundred fifty-three patients were included in the study. The patients were divided into two groups according to their heart rate (70 beats/min and below and above 70 beats/min). Left ventricular and atrial strain analyses were performed in echocardiographic evaluation.
Results: Patients with a resting heart rate of 70 beats/min or less were named group-1(64.2±19), patients with a resting heart rate above 70 beats/min were named group-2(79.1±6.8). Left atrial maximum volüm (60.8±15.5 ml vs. 52.9±16.3 ml p:0.007), left atrial minimum volüm(28.8±9.5 vs. 22.6±7.9 p<0.001), left atrial emptying fraction (52.8±8.5% vs 56.1±8.5% p:0.035), left atrial expansion index (1.19±0.44 vs 1.36±0.47 p:0.044), pLASRcd(-1.3±0.38 vs -1.5±0.61 p:0.031), GLS(-19.3±3 vs. -18.2±2.7 p:0.07) showed difference between group-1 and group-2, respectively. In the multivariable regression analysis, beta-bloker(OR:0.291, 95% CI 0.105-0.810, p:0.018), mean high diastolic blood pressure(OR:1.054, 95% CI 1.009-1.101, p:0.018), left atrial minimum volüme (OR:0.870, 95% Cl 0.809-0.938, p<0.001), S’ (OR:10.6, 95% CI 1.1-104, p:0.041), left atrial expansion index(OR:0.870, 95% CI 0.809-0.930, p<0.033) were determined as independent predictors of high resting heart rate.
Conclusions: Heart rate control emerges as an important goal in patients with hypertension and preserved left ventricular systolic function. Mortality and morbidity can also be improved by the positive effect of heart rate control on GLS.
Substrate pulses as a selection factor for clades of marine Thaumarchaeota
Authors: Hollibaugh James , Damashek Julian , Ducklow Hugh , Popp Brian , Wallsgrove Natalie 
Published: August 2023

Abstract
Oxidation rates of N supplied as ammonium (AO) or urea (UO) by Thaumarchaeota-dominated nitrifying communities in samples of aerobic waters from continental shelf and slope waters of the Southern Ocean west of the Antarctic Peninsula were inhibited by substrate amendments in the low nM range. We found that the response varied consistently by water mass. Rates increased moderately (up to 2-fold) with 44 or 440 vs 6 nM NH4+ amendments to samples from the Winter Water (sampled at 70-80 m), but decreased (down to 7%) in samples from the Circumpolar Deep Water (400-600 m). AO rates decreased more than UO rates. Cell-specific AO rates were lower in CDW samples than in WW samples and chemoautotrophic carbon fixation was also inhibited by NH4+ amendments. We identified similar responses to substrate amendments in data collected elsewhere by others, indicating that inhibition of AO, and to a lesser extent UO, by substrate pulses may be a general phenomenon. Current estimates of nitrification in the epipelagic zone may be ~2-fold greater than in situ, while estimates for the mesopelagic may be ~25% of in situ. Our data suggest that differential adaptation to fluctuating resources may be the basis for the divergence of epipelagic and mesopelagic Thaumarchaeota ecotypes.
Critical Determinants of Delivery Care Services and Socio-economic Factors for Reducing Maternal Mortality in Tanzania.
Authors: Ntemi Petro T 
Published: August 2023

Abstract
Objective:This study examined critical determinants of delivery care services and socio-economic factors in health facilities to reduce MMR in the Tanzanian context.
Methods: The study used 2015-16 Tanzania Demographic and Health Survey and Malaria Indicator Survey as well as the 2012 Tanzania Population and Housing Census data. SPSS software version 25 was used to generate multiple linear regression model between the dependent variable and their respective independent variables.
Results: The study shows MMR was significantly positively related to percentage of women who were assisted by nurses and midwife during delivery, who deliver by caesarean section decided after onset of labor pains and those who complete just primary education, while MMR was negatively related to percentage of women exposed to family planning through doctor or nurse and regional GDP per capita.
Conclusions: The conclusion was that MMR was significantly positively related to the percentage of women who are assisted by nurses and midwives during delivery, who delivered by caesarean section decided after the onset of labor pain and those who complete just primary education, while MMR was significantly negatively related to the percentage of women exposed to family planning through doctors or nurses and regional GDP per capita.
Flexible Circumferential Bioelectronics to Enable 360-degree Recording and Stimulation of the Spinal Cord
Authors: Barone Damiano G. , Woodington Ben , Lei Jiang , Carnicer-Lombarte Alejandro , Güemes Amparo , Naegele Tobias , Hilton Sam , El-Hadwe Salim , Trivedi Rikin , Malliaras George 
Published: August 2023

Abstract
The spinal cord, as an extension of the central nervous system, is one of the most important entities in the body, notably carrying motor information from the brain to the peripheral systems and sensory information from the periphery into the brain. Injuries to the spinal cord can lead to catastrophic effects, including paralysis, pain and autonomic dysfunction.
In this work, we explored the use of thin-film, flexible electronics to circumferentially interface with the spinal cord, leading to a new paradigm of recording and stimulating the dorsal, lateral, and ventral tracts simultaneously using one single device. We validated the capability of the device by recording and stimulating multiple motor and sensory signals around the spinal cord in anaesthetized rats and developed a proof-of-concept closed-loop system to bridge an acute complete spinal cord injury in anaesthetized rodents using dual circumferential devices. We then showed the safety of the device at different time points in freely moving rodents. Finally, we demonstrated that a device of this type could be translated to a human scale using a human cadaver model. This device represents a step change in what is possible to achieve with bioelectronic interfaces in anatomically hard-to-reach areas, unlocking the full potential of the spinal cord. Unlike previous attempts of probing the spinal cord circumferentially, this method sees a clear route to the clinic by using materials and surgical practices that reduce risk during implantation and not affect the integrity of the cord.
Association of chronic pain with suicide attempt and death by suicide: A two-sample Mendelian randomization
Authors: Orri Massimiliano , Balit Jude , Erlangsen Annette , Docherty Anna , Turecki Gustavo 
Published: August 2023

Abstract
Prior studies have suggested an association between chronic pain and suicidal behavior. However, evidence supporting the causal nature of this association, and the role played by depression, remain difficult to establish due to confounding. We investigated associations of chronic pain with suicide attempt and death by suicide as well as the mediating role of depression in this association using a genetically informed method strengthening causal inference. We conducted a two-sample Mendelian randomization. Independent SNPs (N=97) from the Multisite Chronic Pain GWAS (NGWAS=387,649) were used as instrumental variables to test associations of chronic pain with suicide attempt (measured from hospital records; NGWAS=50,264) and death by suicide (measured from official death causes; NGWAS=18,085). Indirect associations of chronic pain with suicide attempt and death by suicide via major depressive disorder (NGWAS=173,005) were estimated. Primary analyses were supported by a range of sensitivity and outlier analyses.We found evidence supporting the contribution of chronic pain to increasing the risk of suicide attempt (OR=1.67, CI=1.21-2.35) and death by suicide (OR=2.00, CI=1.10-3.62). Associations were consistent across sensitivity analysis methods, and no evidence for outliers driving these associations was found. Through mediation analyses, we found that major depressive disorder explained a substantial proportion of the association between chronic pain and suicide attempt (proportion mediated=39%; ORindirect association=1.32, CI=1.09-1.61) and death by suicide (proportion mediated=34%; ORindirect association=1.40, CI=1.13-1.73). Our findings suggest that both pain management interventions and prevention of depression are likely to be effective strategies to reduce suicide risk in individuals with chronic pain.