bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rede de cidades em regiões do interior – oportunidades criadas pela auto-estrada
Authors: Virtudes Ana Lídia 
Published: March 2023

Apresenta-se um estudo das vantagens da organização das cidades em rede através da construção de auto-estra- das em regiões do interior. Baseia-se num caso em Portu- gal, a Região da Beira Interior (RBI). O objectivo central é analisar a valorização socioeconómica da região pela auto-estrada A23, nomeadamente: Oportunidades turísticas ligadas ao património natural e cultural; Organização das cidades em rede e especialização so- cioeconómica. A RBI integra um conjunto das áreas classificadas e protegidas, como a Serra da Estrela, com forte importân- cia ambiental a nível nacional, o que potencia a activida- de turística em relação à qual a A23 é um eixo de acesso determinante e imprescindível, face à falta de alternativas como seja o acesso ferroviário eficaz. A acessibilidade permitida pela A23 transforma estas áreas de paisagem protegida, associadas à protecção da natureza em pólos de atractividade turística, numa região com baixa den- sidade populacional, envelhecimento populacional e te- cido empresarial débil pouco competitivo. A atracção de turistas durante todo o ano, através da A23, é deter- minante para a economia local, pela criação de postos de trabalho e riqueza, onde as alternativas de emprego escasseiam. A A23 promove ganhos de distância/tempo nas des- locações entre as cidades da região, em particular de ca- riz diário residência/local de trabalho. Esta rede urbana multipolar integra um conjunto de aglomerados urbanos, aldeias, vilas e algumas cidades, dos quais se destacam Castelo Branco, Covilhã e Guarda que são as princi- pais âncoras de fixação populacional, pólos promoto- res do desenvolvimento e da dinâmica socioeconómica. A A23 é o elemento de articulação entre eles, promovendo o seu funcionamento em rede, a circulação de pessoas e bens e a especialização funcional de sectores económicos em prol da qualidade e da competitividade às escalas nacional e internacional, dada a proximidade da fronteira.
Mentes Criativas e Espírito Comercial Inovador e as Rendas dos Recursos Naturais nas Regiões Marítimas Remotas
Authors: Dentinho Tomaz P. , Ressurreição Adriana , Santos Ricardo Serrão 
Published: March 2023

O objetivo do artigo é perceber as atitudes criativas e empreendedoras em regiões marítimas ultraperiféricas perante o desafio da Estratégia Marítima Europeia. A hipótese principal a ser testada é que, olhando para a procura crescente de recursos marinhos, a inovação pode ser vista como um fenómeno de procura de rendas não só ao longo do tempo, como é usualmente considerada numa perspetiva Schumpeteriana, mas também ao longo do espaço, onde a afetação ou apropriação de direitos de propriedade tem um efeito importante. Olhamos para as atitudes dos principais interessados pelos recursos marinhos na Horta face às mudanças de direitos de propriedade do mar implícitos na Estratégia Marítima Europeia. Concluímos que a inovação e o desenvolvimento em regiões ultraperiféricas estão fortemente relacionados com a influência que os empreendedores inovadores têm na redefinição dos direitos de propriedade e respetivas rendas dos recursos naturais.
Efectividad en el proceso de cicatrización de heridas abiertas con materiales de bajo costo en un adulto mayor
Authors: Collyer Braga Nowak Juliana , Lopes Almeida Mylene , Barros Santos Israeli , Nowak Benguella Ricardo , Aguilera Gomez David 
Published: March 2023

Actualmente, el número de pacientes con complicaciones relacionadas con el proceso de curación posquirúrgico ha mostrado un aumento significativo. Varios factores contribuyen a la adopción de la curación por segundas intenciones, ya sean complicaciones quirúrgicas, mala higiene en la atención posquirúrgica o imposibilidades anatómicas. Como se sabe, el uso de hidrocoloides en la cicatrización de heridas por segundas intenciones tiene una buena efectividad, sin embargo, su alto costo dificulta que la mayoría de los pacientes los adquieran. Así, el presente estudio tuvo como objetivo analizar materiales accesibles y efectivos para el tratamiento de heridas abiertas y su cicatrización por segunda intención.

Keywords: Healing, Wounds, Healing, Treatment, Low cost.
Abstract
Currently, the number of patients with complications related to the postsurgical healing process has shown a significant increase. Many factors contribute to the adoption of ulterior motive healing, be it surgical complications, poor hygiene in postoperative care, or anatomical impossibilities. As is known, the use of hydrocolloids in wound healing due to ulterior motives has good effectiveness, however their prohibitive cost makes it difficult for most patients to acquire them. Thus, the present study aimed to analyze accessible and effective materials for the treatment of open wounds and their healing by secondary intention.
Nivel de estrés en un equipo de salud de Urgencia y Emergencia de un hospital en el interior de Brasil
Authors: Da Silva Fialho Joilson , Ferreira da Silva Gabriel 
Published: March 2023

El aumento de la esperanza de vida y el salto económico de los avances científicos y medicinales de las últimas generaciones, por un lado, aseguraron grandes beneficios a la población, sin embargo, en contrapartida requirieron una inmensa dedicación al trabajo para aumentar la capacidad de producción, generando grandes jornadas laborales, mayor competitividad del mercado, condiciones estructurales precarias, menores beneficios, además de un menor tiempo para la interacción social, pudiendo someter a las personas de este contexto a un alto nivel de estrés. El sector de Urgencias y Emergencias comprende un entorno de estrés, evidenciando la acumulación de varias condiciones limitantes y agotadoras para el profesional en activo. Por lo tanto, esta investigación tiene como objetivo medir el nivel de estrés observado en los profesionales médicos del sector de Urgencias y Emergencias de un hospital en el interior de Mato Grosso do Sul y conocer su perfil sociodemográfico. Se trata de un estudio exploratorio, con enfoque descriptivo, basado en la metodología de abordaje mixto, en el que participaron 23 profesionales de salud. Para el conocimiento del perfil sociodemográfico se aplicó un cuestionario. Como instrumento de procesamiento de investigación, se utilizó la Escala de Estrés Percibido (EEP) en la versión completa de 14 ítems. El Formulario de Consentimiento, TCLE y TCPE, se firmaron antes de la recopilación de datos. El análisis de las informaciones obtenidas fue procesado por el Software de Datos (SPSS) en su versión 23.0 y por Excel 2019. En suma, se consultó un total de 23 profesionales, donde se constató que en su mayoría eran mujeres, entre 20 y 40 años de edad, católicas, solteras, sin hijos. No son tutores financieros directos de la casa y tienen una sola relación laboral, la mayoría con turnos de 12 horas y carga de trabajo entre 28 y 40 horas semanales, prevaleciendo aquellos con hasta 6 años de experiencia en el sector. En cuanto al nivel de estrés, la mayoría de ellos se posicionaron en estrés moderado a alto. En Chi-cuadrado solo había un vínculo entre el estrés, el tiempo de entrenamiento en el área y el tiempo de experiencia. El Coeficiente alfa fue de 0,034. No se realizó ninguna prueba invasiva o de marcadores bioquímicos, hormonales o biológicos para medir el estrés orgánico. En conclusión, se sugiere la adopción y comercialización de un sistema de organización donde todos los miembros del equipo de enfermería estén involucrados, con el fin de reducir el grado de estrés.
Identification des propriétés psychoacoustiques des acouphènes de huit musiciens et synthèse de portraits acouphéniques
Authors: Augustin Thomas 
Published: March 2023

Cette étude explore les diverses formes prises par l’acouphène sur la base d’une identification des propriétés psychoacoustiques inhérentes à cette sensation auditive fantôme, et à travers la création de portraits acouphéniques. Des entrevues ont été menées auprès de huit participants musiciens qui ont décrit leurs acouphènes et se sont livrés à un protocole de synthèse sonore alliant mesures quantitatives et évaluations qualitatives des percepts. Échantillons sonores, oscillateurs et générateurs de bruits, filtres et autres outils de synthèse ont été utilisés dans l’élaboration de portraits acouphéniques individuels. Ce processus a révélé la pertinence de l’appariement des propriétés psychoacoustiques de la fréquence et de l’intensité généralement mesurées dans une évaluation clinique typique, mais aussi l’évaluation du contenu spectral, des modulations de hauteur et d’amplitude, des enveloppes temporelles et spectrales, de la localisation, et ce pour une multiplicité de percepts chez un même participant. La complexité de ces portraits renvoie à la particularité et la subjectivité de la réalité acouphénique de chacun des sujets, et si l’appariement clinique a pour but premier de donner une tangibilité à l’acouphène, la considération des attributs plus qualitatifs, « comment sonne l’acouphène », accentue cette tangibilité. La mise en forme dans le réel et le partage de cette réalit acouphénique associée à un sentiment d’individualité et d’unicité pourrait faciliter le chemin vers l’acceptation de la condition, spécialement pour des musiciens aptes à discuter de ces particularités psychoacoustiques.
Au diable le gorille ! Les chansons de Georges Brassens en traduction suédoise
Authors: Aronsson Mattias 
Published: March 2023

Cet article porte sur la traduction en suédois des chansons de Georges Brassens. L’objectif de l’étude est de savoir quelles méthodes de traduction ont été utilisées lorsque les chansons ont été transférées dans la langue cible et interprétées par des artistes suédois. Nous avons analysé dix textes cibles à l’aide du système de classification de chansons populaires en traduction de Johan Franzon (2021). Sept d’entre eux se sont révélés très fidèles aux textes sources et ont été classés dans la catégorie desNear-enough translations. Les trois autres textes cibles ne montrent aucun lien aux textes sources et appartiennent à la catégorieAll-new target lyrics. Une tendance vers plus de fidélité envers les textes sources peut être identifiée à partir des années 1980.
L’anxiété de performance dans l’enseignement musical. Une revue de littérature
Authors: Palmeira Ana Paula , Lalitte Philippe 
Published: March 2023

Comment les enseignants de musique pourraient-ils aider leurs élèves pour faire face aux aspects anxiogènes de la représentation en public ? L’objectif de cet article est d’apporter quelques éléments pour répondre à cette question. Il est important de considérer que la représentation en public est l’un des principaux aspects de la pratique musicale dès le début de l’apprentissage. Compte tenu de la forte prévalence de l’anxiété de performance musicale (apm) chez les musiciens de tous les niveaux et de tous les groupes d’âge, l’enseignant a un rôle important. À partir d’une révision de la littérature, les sources de l’apm sont analysées et dans chacune d’elles sont indiquées quelques stratégies qui pourraient être adoptées par l’enseignant. L’accent est mis sur la prévention et sur l’importance de la sensibilisation au sujet de l’apm chez les enseignants de musique.
Effect of Induction Therapy With Olamkicept vs Placebo on Clinical Response in Patients With Active Ulcerative Colitis
Authors: Zhang Shenghong , Chen Baili , Wang Bangmao , Chen Hong , Li Yan , Cao Qian , Zhong Jie , Shieh Ming-Jium , Ran Zhihua , Tang Tongyu , Yang Ming , Xu Beibei , Wang Qiang , Liu Yunjie , Ma Lijia , Wang Xiaolin , Zhang Nan , Zhang Su , Guo Wenyu , Huang Liang , Schreiber Stefan , Chen Minhu 
Published: March 2023

ImportanceOlamkicept, a soluble gp130-Fc-fusion-protein, selectively inhibits interleukin 6 (IL-6) trans-signaling by binding the soluble IL-6 receptor/IL-6 complex. It has anti-inflammatory activities in inflammatory murine models without immune suppression.ObjectiveTo assess the effect of olamkicept as induction therapy in patients with active ulcerative colitis.Design, Setting, and ParticipantsRandomized, double-blind, placebo-controlled phase 2 trial of olamkicept in 91 adults with active ulcerative colitis (full Mayo score ≥5, rectal bleeding score ≥1, endoscopy score ≥2) and an inadequate response to conventional therapy. The study was conducted at 22 clinical study sites in East Asia. Patients were recruited beginning in February 2018. Final follow-up occurred in December 2020.InterventionsEligible patients were randomized 1:1:1 to receive a biweekly intravenous infusion of olamkicept 600 mg (n = 30) or 300 mg (n = 31) or placebo (n = 30) for 12 weeks.Main Outcomes and MeasuresThe primary end point was clinical response at week 12 (defined as ≥3 and ≥30% decrease from baseline total Mayo score; range, 0-12 [worst] with ≥1 decrease and ≤1 in rectal bleeding [range, 0-3 {worst}]). There were 25 secondary efficacy outcomes, including clinical remission and mucosal healing at week 12.ResultsNinety-one patients (mean age, 41 years; 25 women [27.5%]) were randomized; 79 (86.8%) completed the trial. At week 12, more patients receiving olamkicept 600 mg (17/29 [58.6%]) or 300 mg (13/30 [43.3%]) achieved clinical response than placebo (10/29 [34.5%]), with adjusted difference vs placebo of 26.6% (90% CI, 6.2% to 47.1%; P = .03) for 600 mg and 8.3% (90% CI, −12.6% to 29.1%; P = .52) for 300 mg. Among patients randomized to receive 600 mg olamkicept, 16 of 25 secondary outcomes were statistically significant compared with placebo. Among patients randomized to receive 300 mg, 6 of 25 secondary outcomes were statistically significant compared with placebo. Treatment-related adverse events occurred in 53.3% (16/30) of patients receiving 600 mg olamkicept, 58.1% (18/31) receiving 300 mg olamkicept, and 50% (15/30) receiving placebo. The most common drug-related adverse events were bilirubin presence in the urine, hyperuricemia, and increased aspartate aminotransferase levels, and all were more common in the olamkicept groups compared with placebo.Conclusions and RelevanceAmong patients with active ulcerative colitis, biweekly infusion of olamkicept 600 mg, but not 300 mg, resulted in a greater likelihood of clinical response at 12 weeks compared with placebo. Further research is needed for replication and to assess longer-term efficacy and safety.Trial RegistrationClinicalTrials.gov Identifier: NCT03235752
Event‐triggered distributed model predictive control scheme for temperature regulation in multi‐zone air conditioning systems with improved indoor thermal preference indicator
Authors: Gao Jingjing , Yang Xu , Zhang Shilong , Tu Rang , Ma Hongjun 
Published: March 2023

SummaryDriven by the increasing needs in multi‐zone buildings for reducing the air conditioning (A/C) system related energy consumption and increasing the occupants' thermal comfort, an event‐triggered distributed model predictive control (DMPC) scheme for building temperature regulation with improved indoor thermal preference indicator is proposed. To this end, a temperature‐energy model of the A/C system in a zone which considers multiple types of heat transfer, and the system model of the multi‐zone A/C system are derived first. On this basis, an improved indoor thermal preference indicator that trades off the A/C systems related energy consumption with the aggregate thermal comfort of the occupants is proposed for the multi‐zone A/C system, then the optimal indoor temperature set‐points for each zone are determined by using the distributed consensus algorithm. It is followed by an event‐triggered DMPC scheme by adjusting the A/C systems to arrive at the optimal indoor temperature set‐points for all the zones with lower communication and computation load. The performance and effectiveness of the proposed methods are demonstrated through a case study on an actual multi‐zone A/C system.
Dynamic Ion Sieve as the Buffer Layer for Regulating Li+ Flow in Lithium Metal Batteries
Authors: Huang Junda , He Jian , Liu Quanhui , Ma Jianmin 
Published: March 2023

AbstractHow to realize uniform Li+ flow is the key to achieve even Li deposition for lithium metal batteries (LMBs). In this study, a concept of dynamic ion sieve is proposed to design the buffer layer nearby Li anode surface to regulate Li+ spatial arrangement by introducing tributylmethylphosphonium bis(trifluoromethanesulfonyl)imide (TMPB) into the carbonate electrolyte. The buffer layer induced by TMP+ can adjust the velocity of arriving solvated Li+ that gives solvated Li+ sufficient time to redistribute and accumulate on Li anode surface, resulting in a uniform and higher concentrated Li+ flow. Besides, TFSI− can participate in the generation of inorganic component‐rich solid electrolyte interphase (SEI) with Li3N, which can facilitate the Li+ conductivity of SEI. Consequently, the stable and uniform Li deposition can be obtained, achieving the excellent cycling performance up to 1000 h at 0.5 mA cm−2 in the Li||Li symmetric cell. Besides, the Li||NCM622 full cell also possesses excellent cycling stability with a high‐capacity retention rate of 66.7% after 300 cycles.
Light‐Fueled Nonequilibrium and Adaptable Hydrogels for Highly Tunable Autonomous Self‐Oscillating Functions
Authors: Yang Xuehan , Shi Wencheng , Chen Zhe , Du Mengqi , Xiao Shiyan , Qu Shaoxing , Li Chuang 
Published: March 2023

AbstractNonequilibrium oscillation fueled by dissipating chemical energy is ubiquitous in living systems for realizing a broad range of complex functions. The design of synthetic materials that can mimic their biological counterparts in the production of dissipative structures and autonomous oscillations is of great interest but remains challenging. Here, a series of environmentally adaptable hydrogels functionalized with photoswitchable spiropyran derivatives that display a tunable equilibrium‐shifting capability, thus endowing those hydrogels with a high degree of freedom and flexibility is reported. Such nonequilibrium hydrogels are able to responsively adapt their shapes under constant light illumination due to asymmetric deswelling, which in turn generates self‐shadowing and consequently creates autonomous self‐oscillating behaviors through a negative feedback process. Diverse oscillation modes including bending, twisting, and snap‐through buckling with tunable frequency and amplitude are widely observed in three different molecular systems. Density functional theory calculations and finite element simulations further demonstrated the robustness of such a photoadaptable self‐oscillation mechanism. This study provides a useful molecular design strategy for construction of highly adaptable hydrogels with potential applications in self‐sustained soft robots and autonomous devices.
In Operando Optical Tracking of Oxygen Vacancy Migration and Phase Change in few Nanometers Ferroelectric HZO Memories
Authors: Jan Atif , Rembert Thomas , Taper Sunil , Symonowicz Joanna , Strkalj Nives , Moon Taehwan , Lee Yun Seong , Bae Hagyoul , Lee Hyun Jae , Choe Duk‐Hyun , Heo Jinseong , MacManus‐Driscoll Judith , Monserrat Bartomeu , Di Martino Giuliana 
Published: March 2023

AbstractFerroelectric materials offer a low‐energy, high‐speed alternative to conventional logic and memory circuitry. Hafnia‐based films have achieved single‐digit nm ferroelectricity, enabling further device miniaturization. However, they can exhibit nonideal behavior, specifically wake‐up and fatigue effects, leading to unpredictable performance variation over consecutive electronic switching cycles, preventing large‐scale commercialization. The origins are still under debate. Using plasmon‐enhanced spectroscopy, a non‐destructive technique sensitive to <1% oxygen vacancy variation, phase changes, and single switching cycle resolution, the first real‐time in operando nanoscale direct tracking of oxygen vacancy migration in 5 nm hafnium zirconium oxide during a pre‐wake‐up stage is provided. It is shown that the pre‐wake‐up leads to a structural phase change from monoclinic to orthorhombic phase, which further determines the device wake‐up. Further migration of oxygen ions in the phase changed material is then observed, producing device fatigue. These results provide a comprehensive explanation for the wake‐up and fatigue with Raman, photoluminescence and darkfield spectroscopy, combined with density functional theory and finite‐difference time‐domain simulations.
Room‐Temperature Exceptional‐Point‐Driven Polariton Lasing from Perovskite Metasurface
Authors: Masharin M.A. , Samusev A.K. , Bogdanov A.A. , Iorsh I.V. , Demir H.V. , Makarov S.V. 
Published: March 2023

AbstractExcitons in lead bromide perovskites exhibit high binding energy and high oscillator strength, allowing for a strong light‐matter coupling regime in the perovskite‐based cavities localizing photons at the nanoscale. This opens up the way for the realization of exciton‐polariton Bose–Einstein condensation and polariton lasing at room temperature – the inversion‐free low‐threshold stimulated emission. However, polariton lasing in perovskite planar photon cavities without Bragg mirrors has not yet been observed and proved experimentally. In this study, perovskite metasurface is employed, fabricated with nanoimprint lithography, supporting so‐called exceptional points to demonstrate the room‐temperature polariton lasing. The exceptional points in exciton‐polariton dispersion of the metasurface appear upon optically pumping in the nonlinear regime in the spectral vicinity of a symmetry‐protected bound state in the continuum providing high mode confinement with the enhanced local density of states beneficial for polariton condensation. The observed lasing emission possesses high directivity with a divergence angle of 1° over one axis. The employed nanoimprinting approach for solution‐processable large‐scale polariton lasers is compatible with various planar photonic platforms suitable for on‐chip integration.
Enzymatic Self‐Assembly of Adamantane‐Peptide Conjugate for Combating Staphylococcus aureus Infection
Authors: Zhan Wenjun , Gao Ge , Liu Zhiyu , Liu Xiaoyang , Xu Lingling , Wang Manli , Xu Hai‐Dong , Tang Runqun , Cao Jingyuan , Sun Xianbao , Liang Gaolin 
Published: March 2023

AbstractStaphylococcus aureus (S. aureus) remains a leading cause of bacterial infections. However, eradication of S. aureus infections with common antibiotics is increasingly difficult due to outbreaks of drug resistance. Therefore, new antibiotic classes and antibacterial strategies are urgently in demand. Herein, it is shown that an adamantane‐peptide conjugate, upon dephosphorylation by alkaline phosphatase (ALP) constitutively expressed on S. aureus, generates fibrous assemblies in situ to combat S. aureus infection. By attaching adamantane to a phosphorylated tetrapeptide Nap‐Phe‐Phe‐Lys‐Tyr(H2PO3)‐OH, the rationally designed adamantane‐peptide conjugate Nap‐Phe‐Phe‐Lys(Ada)‐Tyr(H2PO3)‐OH (Nap‐FYp‐Ada) is obtained. Upon bacterial ALP activation, Nap‐FYp‐Ada is dephosphorylated and self‐assembles into nanofibers on the surface of S. aureus. As revealed by cell assays, the assemblies of adamantane‐peptide conjugates interact with cell lipid membrane and thereby disrupt membrane integrity to kill S. aureus. Animal experiments further demonstrate the excellent potential of Nap‐FYp‐Ada in the treatment of S. aureus infection in vivo. This work provides an alternative approach to design antimicrobial agents.