bluuebunny/crossref_metadata_2025_split huggingface dataset:
An Actionable Expert-System Algorithm to Support Nurse-Led Cancer Survivorship Care: Algorithm Development Study
Authors: Pfisterer Kaylen J , Lohani Raima , Janes Elizabeth , Ng Denise , Wang Dan , Bryant-Lukosius Denise , Rendon Ricardo , Berlin Alejandro , Bender Jacqueline , Brown Ian , Feifer Andrew , Gotto Geoffrey , Saha Shumit , Cafazzo Joseph A , Pham Quynh 
Published: August 2023

Background
Comprehensive models of survivorship care are necessary to improve access to and coordination of care. New models of care provide the opportunity to address the complexity of physical and psychosocial problems and long-term health needs experienced by patients following cancer treatment.

Objective
This paper presents our expert-informed, rules-based survivorship algorithm to build a nurse-led model of survivorship care to support men living with prostate cancer (PCa). The algorithm is called No Evidence of Disease (Ned) and supports timelier decision-making, enhanced safety, and continuity of care.

Methods
An initial rule set was developed and refined through working groups with clinical experts across Canada (eg, nurse experts, physician experts, and scientists; n=20), and patient partners (n=3). Algorithm priorities were defined through a multidisciplinary consensus meeting with clinical nurse specialists, nurse scientists, nurse practitioners, urologic oncologists, urologists, and radiation oncologists (n=17). The system was refined and validated using the nominal group technique.

Results
Four levels of alert classification were established, initiated by responses on the Expanded Prostate Cancer Index Composite for Clinical Practice survey, and mediated by changes in minimal clinically important different alert thresholds, alert history, and clinical urgency with patient autonomy influencing clinical acuity. Patient autonomy was supported through tailored education as a first line of response, and alert escalation depending on a patient-initiated request for a nurse consultation.

Conclusions
The Ned algorithm is positioned to facilitate PCa nurse-led care models with a high nurse-to-patient ratio. This novel expert-informed PCa survivorship care algorithm contains a defined escalation pathway for clinically urgent symptoms while honoring patient preference. Though further validation is required through a pragmatic trial, we anticipate the Ned algorithm will support timelier decision-making and enhance continuity of care through the automation of more frequent automated checkpoints, while empowering patients to self-manage their symptoms more effectively than standard care.

International Registered Report Identifier (IRRID)
RR2-10.1136/bmjopen-2020-045806
SEMANGAT PATRIOTISME PADA PUISI AL HARB TA’MAL BIL JID KARYA DUNYA MIKHAIL DAN DOA SERDADU SEBELUM BERPERANG KARYA WS RENDRA (ANALISIS SASTRA BANDING)
Authors: Nasri Azwar 
Published: August 2023

penulisan artkel ini bertujuan untuk mengetahui semangat patriotisme yang digambarkan didalam puisi alharbu takmal bil jid karya dunya Mikhail dan doa serdadu sebelum bereperang karya ws rendra. penulis menghadirkan dua puisi yang berbeda Negara dan bahasa, dengan menggunakan teori sastra bandingan. Pendekatan yang digunakan dalam penulisan artikel ini adalah deskriptif kualitatif. Adapun metode dalam pengumpulan data menggunakan metote dengan membaca dan mencatat. Dengan membaca penulis menemukan data-data yang mendukung penelitian. Adapun dalam menggunakan metode catat akan membantu dalam merapikan data. Hasil dari penelitian sastra bandingan ini terdapat Unsur kesamaan dan perbedaan pada dua puisi ini. persamaanya tema dan narasi untuk memperjuangkan kemerdekaan Negara. Adapun poin yang berbeda pada tifografi puisi.
Desarrollo del Crowdlending para las Pymes en Colombia bajo la plataforma A2censo
Authors: Zamora - Morantes Carlos Hildar , Oviedo Elizabeth 
Published: August 2023

La revolución 4.0, las constantes crisis que circundan el desarrollo empresarial que impactan en el país y la búsqueda de oportunidades de pequeños inversionistas con bajos recursos obligan no solo a modernizar sino a cambiar la idea de crédito como mecanismo que apalanca oportunidades dejando a un lado las reglas de un “único” oferente o aportante financiero, el cual puede influir en la exclusión o en la limitación de la cantidad solicitada por el prestatario, para que logre ser un mecanismo accesible a las propuestas, reales en el tiempo, con los aportes de distintos inversores y el apoyo activo del intermediario para su logros de las PYMES. Se trata de un trabajo de corte descriptivo que tiene como objetivo presentar la caracterización del Crowdlending en Colombia llegando al contraste con otras plataformas de inversión a partir de la revisión documental. A grandes rasgos, la presencia de “prestamos colectivos” permite que las PYMES (en su mayoría pequeñas empresas, con menos de 5 años y del sector manufacturero) contar con un crédito accesible, permitiéndoles, por medio del acompañamiento de la plataforma, suplir sus necesidades de capital de trabajo.
El Emprendimiento en la educación agrícola a la luz de tres enfoques epistemológicos: Una revisión sistemática
Authors: Villamarín - Monroy Jeffer Julián , Montalvo - Rodríguez Juan Carlos 
Published: August 2023

Una de las maneras para superar las necesidades económicas y productivas de las diferentes zonas rurales, es a través del emprendimiento. Por este motivo estudiar desde epistemologías como la fenomenología, el constructivismo, y el empirismo, logra abarracar las diferentes preguntas y brechas que se presentan en las incidencias para el desarrollo formación de los jóvenes en actividades de emprendimiento agrícola. Sin embargo, el emprendimiento da soluciones a las problemáticas sociales en cada una de las regiones. De esta manera también logra estimular en los jóvenes de los colegios agrícolas nociones de emprendimiento, y genera aportes en la transformación de los entornos, aumentando las dinámicas económicas adaptadas en las regiones, que finalmente aportan al desarrollo de los jóvenes, y la obtención de capacidades en emprendimiento. Se realiza una revisión sistemática de artículos publicados en revistas indexadas en inglés y español de aportes investigativos en temas de formación en emprendimiento agrícola, las experiencias que se dan de acuerdo con las condiciones y características de cada uno de los diferentes estudios realizados, y su adaptabilidad en los entornos rurales a partir de los paradigmas que enmarcan estas condiciones en cada una de las regiones a nivel global.
Adherence to a Web-based Exercise Programme: A Feasibility Study Among Patients with Hip or Knee Osteoarthritis
Authors: Joseph Kenth-Louis , Dagfinrud Hanne , Hagen Kåre Birger , Nordén Kristine Røren , Fongen Camilla , Wold Ole-Martin , Hinman Rana S. , Nelligan Rachel K. , Bennell Kim L. , Tveter Anne Therese 
Published: August 2023

Objectives: To describe adherence to a 12-week web-based aerobic exercise programme, to compare characteristics between those who adhere or not, and to identify barriers for exercising in patients with hip or knee osteoarthritis.
Design: Single-arm feasibility study.
Subjects: Patients with hip or knee osteoarthritis in specialist healthcare, age 40–80 years, and not candidates for joint surgery.
Methods: Adherence to a 12-week exercise programme was defined as having completed ≥ 2 exercise sessions a week for at least 8 weeks. Baseline differences between adherent and non-adherent groups in demographics, symptoms, disability, physical activity and fitness were assessed using Mann–Whitney U or χ2 tests. Reasons for not completing exercise sessions were reported in weekly diaries.
Results: A total of 29 patients (median age 64 years, 72% female) were included. Median baseline pain (numerical rating scale 0–10) was 5. Fifteen patients adhered to the exercise programme, 14 did not. Non-adherent patients were less active (p = 0.032) and had lower cardiorespiratory fitness (p = 0.031). The most frequently reported barrier to exercising was sickness. Less than 10% reported pain as a barrier.
Conclusion: Half of the patients with hip or knee osteoarthritis adhered to the digitally delivered exercise programme and the most frequently reported barrier for adherence was sickness, while less than 10% reported pain as a reason for not exercising.
Trial registration: ClinicalTrials.gov, NCT04084834. The Regional Committee for Medical and Health Research Ethics South-East, 2018/2198.
Características, focos de pesquisa e tendências sobre liderança na gestão de projetos: uma análise bibliométrica
Authors: Casemiro Ítalo Paula , Azevedo-Ferreira Maxwel De 
Published: August 2023

Objetivo: A literatura científica destaca o papel fundamental que a liderança exerce na gestão de projetos. Tendo em vista a relevância da liderança na gestão de projetos, o presente estudo objetiva mapear a produção científica acerca da temática liderança, no âmbito da gestão de projetos.
Método: O estudo foi conduzido por meio de uma análise bibliométrica de 789 artigos obtidos na base Web of Science. apresenta uma série de indicadores e tendências predominantes nas pesquisas acerca da liderança em projetos. Os estudos foram analisados com o auxílio dos softwares Bibliometrix R-tool e VosViewer, por meio de indicadores bibliométricos.
Principais Resultados: O estudo destaca um número crescente de publicações, focadas especialmente em competências da liderança. Estados Unidos é o país expoente na produção, e o periódico International Journal of Project Management é aquele mais utilizado para a publicação sobre este tópico. A análise temática, identificou alguns agrupamentos temáticos, com destaque para temas básicos/tradicionais, como a inovação, gestão da mudança e equipe de projeto e; temas motores como a sustentabilidade, trabalho em equipe e outros mais recentes, como a melhoria contínua em projetos.
Relevância/Originalidade: A pesquisa apresenta um panorama da pesquisa sobre liderança na gestão de projetos, oferecendo insights importantes sobre estas duas áreas de conhecimento: liderança e gestão de projetos.
Contribuições Teóricas: O presente documento oferece aos gestores e interessados na liderança em projetos uma base útil para o desenvolvimento de programas de liderança e futuras pesquisas sobre o tema, no âmbito da liderança em projetos.
INSLISLITE EVALUATION IN THE PROCESSING OF LIBRARY MATERIALS TOWARD USABILITY MODEL
Authors: Putri Indira Adiadwi , RA Okta Reni Azrina , Kesuma Aghesna Rahmatika , Iqbal Rahmat 
Published: August 2023

An information system can ease the user in receiving information. The library needs to use effective and efficient service by using the information system. Processing of library materials is important to do to facilitate the search for information and expedite service activities. This research has a case study at the Bandar Lampung City Library and Archives Service which has used the INLISLite system since 2014. But until now they are still using INLISLite version 3.1. This study uses a qualitative descriptive method by conducting field research on the problems that occur, as well as interacting directly with librarians. INLISLite version 3.1 which is used displays several menus such as Back Office, Read on Place, Guest Book, Online Membership, Digital Collection Services, OPAC, Articles, Member Registration, Statistics, Surveys, Self-Returns, and Self Borrowing. The results first result from the study, librarians can process library materials on the Back Office menu. The second is there are no problems in the learnability and efficiency aspects because in this aspect the INLISLite system makes it very easy for librarians, but there are problems in the Memorability, Error, and Satisfaction aspects.
Impactos del Sistema Tributario en el modelo de descuento de flujos de fondos
Authors: Milanesi Gaston Silverio , Tennina Maria Agustina 
Published: August 2023

La determinación del valor de los ahorros fiscales y el impacto del impuesto a la renta en la valuación de empresa depende del sistema tributario vigente en el mercado. Los efectos fiscales que implican pagos y ahorros deben analizarse con el sistema tributario donde opera la firma. Los trabajos de Modigliani y Miller (1963) y Miller (1977) suponen un sistema clásico de imposición a la renta. La Organización Mundial del Comercio (OCDE) identifica siete sistemas tributarios clasificados en dos grandes grupos: integrados y clásicos. El trabajo revisa los modelos existentes, particularmente el Modelo General. Seguidamente, expone las ecuaciones de valor correspondientes a los diferentes sistemas tributarios. Mediante un análisis de casos se analiza el impacto en las variables del sistema tributario en el que opera la firma, según los sistemas clasificados por la OCDE.
Cost-effectiveness of empagliflozin in heart failure patients irrespective of ejection fraction in England
Authors: Kolovos Spyros , Bellanca Leana , Groyer Harinala , Rosano Giuseppe , Gaultney Jennifer , Linden Stephan 
Published: August 2023

Aims
Heart failure (HF) is a complex syndrome commonly categorized into two main phenotypes [left ventricular ejection fraction (LVEF) below or above 40%], and although empagliflozin is the first approved medication with proven clinical effectiveness for both phenotypes, its cost-effectiveness of treating the entire HF population remains unknown.

Methods
The analysis was performed utilizing two preexisting, LVEF phenotype-specific cost-effectiveness models to estimate the cost-effectiveness of empagliflozin in adults for the treatment of symptomatic chronic HF, irrespective of ejection fraction (EF). The results of the phenotype-specific models were combined using a population-weighted approach to estimate the deterministic and probabilistic incremental cost-effectiveness ratios (ICERs).

Results
Based on combined results, empagliflozin + standard of care (SoC) is associated with 6.13 life-years (LYs) and 3.92 quality-adjusted life-years (QALYs) compared with 5.98 LYs and 3.76 QALYs for SoC alone over a lifetime, resulting in an incremental difference of 0.15 LYs and 0.16 QALYs, respectively. Total lifetime healthcare costs per patient are £15 246 for empagliflozin + SoC and £13 982 for SoC giving an incremental difference of £1264. The ICER is £7757/QALY, which is substantially lower than the willingness-to-pay (WTP) of £30 000 per QALY used by NICE. The results of the probabilistic sensitivity analyses are in line with the deterministic results.

Conclusion
Empagliflozin is the first efficacious, approved, and cost-effective treatment option for all HF patients, irrespective of EF. The combined ICER was consistently below the WTP threshold. Therefore, empagliflozin offers value for money for the treatment of the full HF population in England.
Trends in occurrence of takotsubo syndrome and association with SARS-CoV-2 infection and COVID-19 vaccination
Authors: Rosh Bar , Naoum Ibrahim , Stein Nili , Jaffe Ronen , Saliba Walid 
Published: August 2023

Aims
Takotsubo syndrome (TTS) is a serious heart disease associated with significant morbidity and mortality. TTS has been related to SARS-CoV-2 infection and COVID-19 vaccine; however, the current data are scarce. We aimed to examine the associations between SARS-CoV-2 infection and its vaccine with TTS.

Methods
We conducted a nested case–control study in a cohort of 3 237 909 adults from the largest healthcare provider in Israel. Patients were followed from 1 March 2020 until 31 December 2021 for the occurrence of TTS. Ten randomly selected controls were matched to each case of TTS on age, sex, and duration of follow-up. Exposure to SARS-CoV-2 infection and COVID-19 vaccine in the prior 30 days was assessed in cases and controls.

Results
During the follow-up 144 patients developed TTS and were matched to 1440 controls. The mean age of cases and their matched controls was 71.4 ± 12 years, and 136 (94.4%) of them were women. Conditional logistic regression analysis showed that SARS-CoV-2 infection and COVID-19 vaccine were not associated with an increased risk of TTS; odds ratio (OR) = 2.04 [95% confidence interval (CI), 0.50–8.2] and 0.87 (0.49–1.54), respectively. The absolute number of TTS cases in the prepandemic period (March–December 2018–2019) was 82 in 2018 and 80 in 2019. The number of TTS cases decreased to 56 during the corresponding period of 2020 (first pandemic year) and increased back to 81 in 2022.

Conclusion
No significant association was found between SARS-CoV-2 infection or COVID-19 vaccination and TTS occurrence.
Mitral valve surgery in acute infective endocarditis: long-term outcomes of mitral valve repair versus replacement
Authors: Di Bacco Lorenzo , D’Alonzo Michele , Di Mauro Massimiliano , Petruccelli Rocco Davide , Baudo Massimo , Palacios Camila Mayorga , Benussi Stefano , Muneretto Claudio , Rosati Fabrizio 
Published: August 2023

Aims
Timing and surgical strategies in acute infective endocarditis are still questionable. We sought to investigate clinical outcomes of patients undergoing mitral valve repair (MVR) compared with mitral valve replacement [mitral valve prosthesis (MVP)] for acute infective endocarditis.

Methods
From 2004 to 2019, 109 consecutive patients with acute mitral valve infective endocarditis were retrospectively investigated. Patients were divided into two groups according to surgical strategy: MVR 53/109 (48.6%) versus MVP 56/109 (51.4%). Primary end points were in-hospital mortality and overall survival at 10 years. Secondary end point was the freedom from infective endocarditis relapse.

Results
Our institutional surgical approach for infective endocarditis allowed us to achieve MVR in 48.6% of patients. Hospital mortality was comparable between the two groups [MVR: 1/53 (1.9%) versus MVP: 2/56 (3.6%), P = 1.000]. Overall 10-year survival was 80.0 ± 14.1 and 77.2 ± 13.5% for MVR and MVP, respectively (P = 0.648). MVR showed a lower incidence of infective endocarditis relapse compared with MVP (MVR: 93.6 ± 7.1 versus MVP: 80.9 ± 10.8%, P = 0.041). At Cox regression, infective endocarditis relapse was an independent risk factor for death (hazard ratio 4.03; 95% confidence interval 1.41–11.52; P = 0.009).

Conclusion
The tendency to postpone surgery in stable patients with mitral infective endocarditis allowed achievement of MVR in almost 50% of patients. Although repair remains the approach of choice in our institution, no differences between MVR and MVP were reported in terms of early/late survival. However, MVP had a higher incidence of infective endocarditis relapse that represents an independent risk of mortality.
Twenty years of clear aligner therapy: a bibliometric analysis (2002-2022)
Authors: Gong Beiwen , Liu Ziyang , Yang Liya , Sun Xiaomei , Lu Jianjian , Teng Li , Bai Yuxing , Xie Xianju 
Published: August 2023

Abstract

Introduction
Clear aligner (CA) therapy has become popular worldwide but there is little research in the area from the perspective of bibliometrics. The present study aimed to identify the most impactful studies on CA over its 20 years of publishing since 2002.

Methods
The Web of Science database was used to retrieve study records on CA for the period between 2002 and 2022. Two authors manually screened the related studies. CiteSpace was used to analyse the country and institutional co-operation, keywords and citations with the strongest ‘burst’.

Results
The number of CA publications has increased and a total of 613 studies were included in the current analysis. The American Journal of Orthodontics and Dentofacial Orthopedics was the leading publishing journal reporting 79 published CA articles and 1627 total citations. Italy had the most significant productivity in this field (142/613, 23.16%). The United States of America was the leading country with the highest international collaboration. Based on the results of keyword analysis, orthodontic treatment, digital orthodontics, superimposition, and apical root resorption were previous research emphases.

Conclusions
The present analysis indicates that the treatment outcomes of CA therapy is the focus of current studies and provides developments for future research. The results provide an increased and comprehensive understanding of the state of the art of CA treatment.
Comparison of the cytotoxicity of 3D-printed aligners using different post-curing procedures: an in vitro study
Authors: Alessandra Campobasso , Anastasia Ariano , Giovanni Battista , Francesca Posa , Marco Migliorati , Sara Drago , Eleonora Lo Muzio , Giorgio Mori 
Published: August 2023

Abstract

Objective
Three-dimensional (3D) printing technology represents a novel method for manufacturing aligners. The aim of the present study was to assess the in-vitro cytotoxicity of 3D-printed aligners using different post-polymerisation conditions.

Materials
Aligners were printed using the same 3D-print resin (TC-85DAC, Graphy, Seoul, Korea) and printer (AccuFab-L4D, Shining 3D Tech. Co., Hangzhou, China), followed by different post-curing procedures. Six aligners were post-polymerised for 14 min using the Tera Harz Cure and a nitrogen generator curing machine (THC2, Graphy, Seoul, Korea) (P1). A further six aligners were post-cured for 30 min on each side using the Form Cure machine (FormLabs Inc, Somerville, USA) (P2). The aligners were cut into smaller specimens (2 mm×2 mm) and sterilised at 121°C. The specimens were placed in 96-well plates containing Dulbecco’s Modified Eagle’s Medium (DMEM) at 37° for 7 or 14 days. The viability of MC3T3E-1 pre-osteoblasts cultured with DMEM was evaluated using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The optical density of each cell culture was measured to assess cell viability, following which the data were statistically analysed using two-way and one-way ANOVA (α = 0.05).

Results
The comparison of cytotoxicity revealed statistically significant differences between post-curing procedures and MTT timings (P < 0.001). After 7 and 14 days, the cell viability of P2 was significantly reduced compared to P1 and the control groups (P < 0.001), while P1 showed no significant differences compared to the controls. Overall, P2 post-curing exhibited moderate cytotoxicity, while P1 post-polymerisation was highly biocompatible.

Conclusions
Different post-curing procedures may affect the in-vitro cytotoxicity of 3D-printed aligners. Clinicians should adhere to the manufacturer’s recommendations when using 3D-print resin.