bluuebunny/crossref_metadata_2025_split huggingface dataset:
Crosstalk Between Autophagy and Inflammation in Chronic Cerebral Ischaemia
Authors: Zhou Hai-qian , Zhang Li-mei , Li Xiao , Huang Zhi-hua 
Published: March 2023

AbstractChronic cerebral ischaemia (CCI) is a high-incidence cardiovascular and cerebrovascular disease that is very common in clinical practice. Although many pathogenic mechanisms have been explored, there is still great controversy among neuroscientists regarding the pathogenesis of CCI. Therefore, it is important to elucidate the mechanisms of CCI occurrence and progression for the prevention and treatment of ischaemic cerebrovascular disorders. Autophagy and inflammation play vital roles in CCI, but the relationship between these two processes in this disease remains unknown. Here, we review the progression and discuss the functions, actions and pathways of autophagy and inflammation in CCI, including a comprehensive view of the transition from acute disease to CCI through ischaemic repair mechanisms. This review may provide a reference for future research and treatment of CCI.
Graphical Abstract
Schematic diagram of the interplay between autophagy and inflammation in CCI. CCI lead to serious, life-threatening complications. This review summarizes two factors in CCI, including autophagy and inflammation, which have been focused for the mechanisms of CCI. In short, the possible points of intersection are shown in the illustration. CCI, Chronic cerebral ischaemia; ER stress, Endoplasmic reticulum stress; ROS, Reactive oxygen species.
Religiosity of Migrants and Natives in Western Europe 2002–2018: Convergence and Divergence
Authors: Guveli Ayse , Platt Lucinda 
Published: March 2023

AbstractPatterns of religiosity among both settled and migrant populations have been the subject of intense, and often conflicting, scholarly debate. In Europe, most analysis of migrant religiosity has focused on Islam, though migrants to Western European countries come from a wide range of religions and denominations. Despite a general assumption of assimilation over generations to greater secularization, evidence on trends in religiosity across migrants of different religions and for both first and second generations remains partial. We use the European Social Survey (rounds 1–9) to examine three dimensions of religiosity encompassing both performative and subjective domains, across 15 Western European destination countries over a 16-year period. While variation in religiosity between different affiliations is not large, migrants tend to have higher religiosity than non-migrants across the religious affiliations we consider. Over time we see that while natives show an overall decline in religiosity over the period, first- and second-generation Protestants and Muslims show increases in religiosity, providing some evidence for religious revival. We discuss the implications of our findings for theories of secularization and religious revival, and the future religious landscape of Europe.
Roundtable on Deregistration and Gender Law Reform Internationally
Authors: Smith Jess , Cannoot Pieter , de Repentigny Pierre Cloutier , Holzer Lena , Leung Shelley , Ni Mhuirthile Tanya , Vipond Evan , Varman Nipuna 
Published: March 2023

AbstractIn this roundtable discussion, early-career researchers working in the field of law, gender, and sexuality discuss international and trans-national developments to legal gender. ‘The Future of Legal Gender’ research project focused on the legislative framework of England and Wales to develop a prototype for decertification. The domestic legislation, however, was situated within a wider international context throughout the project. This roundtable discussion, therefore, provided an opportunity for reflection on the transnational issues raised by decertification, with a particular focus on developments arising in the jurisdiction(s) studied by the early career researchers. The roundtable began with a brief outline of these recent developments before moving to an open discussion on key themes including the value of reform on wider society, changes on-the-ground by non-state actors, and alternative processes for tackling gender inequalities without certifying legal gender. The online conversation took place on 28 June 2021 and has been transcribed and edited for continuity, clarity, and referencing.
Characterization of an Iron Ore Tailing Sample and the Evaluation of Its Representativeness
Authors: Carneiro Jessé Joabe Vieira , Marques Eduardo Antonio Gomes , Viana da Fonseca António Joaquim Pereira , Ferraz Roberto Lopes , Oliveira Ângelo Henrique Cruz 
Published: March 2023

AbstractThe massive annual tonnage of iron ore tailings, plus the more demanding environmental policies after the catastrophic collapses of Fundão Dam in 2015 and Feijão Dam I in 2019, have forced Brazilian mining companies to search for more sustainable and safer alternatives for tailings disposal. The Brazilian mining industry has been studying the dry stacking of filtered tailings. Most companies seek the development of great dry stacks, over 200 m high, to absorb the whole tailings generation. As tailings assume a structural role, it is vital to characterize the dry stacks and understand their behaviour. This study aimed to characterize index properties, evaluate the effect of compaction on the hydraulic behaviour, and evaluate field variability of iron ore tailings from a mine in Quadrilátero Ferrífero, Brazil. Also, a database of iron ore tailings properties from Quadrilátero Ferrífero was collected and used to evaluate the results. Specimens were compacted to 93%, 95%, 97%, and 100% of Proctor’s maximum dry unit weight, and the hydraulic conductivity was defined for several confining pressures (100, 200, 400, 800, 1600 and 1900 kPa) for each degree of compaction. Index properties of the studied tailing were similar to other iron ore tailings from the Quadrilátero Ferrífero, hydraulic conductivity was proportional to the void ratio, and the field tests indicated some variability of both material properties and degree of compaction of the stacked material. The database presented in this study supplies the mining industry with a reference point for future projects.
Studying abroad experience and the wages of females
Authors: Asankulova Zhanylai , Thomsen Stephan 
Published: March 2023

AbstractStudying abroad acts as investment in human capital and ideally outweighs associated investment costs due to higher earnings or related non-monetary benefits. We estimate monetary returns to studying abroad for female graduates 1 and 5 years after graduation. The empirical estimates—based on panel data from four graduate cohorts in 1997, 2001, 2005, and 2009—confirm positive returns to studying abroad. Mobile females earn 3.2% higher wages compared to non-mobiles at labor market entry. These initial wage gains tend to improve further over time, resulting in about 4.0% higher earnings for mobile females 5 years after graduation. Detailed consideration of different socio-economic groups reveals that female graduates from non-academic backgrounds and females majoring in social sciences benefit most. Studying abroad, therefore, has positive effects on later income of female graduates.
Ethanol preservation effects on stable carbon, nitrogen and hydrogen isotopes in the freshwater pearl mussel
Authors: Hajisafarali Mahsa , Taskinen Jouni , Eloranta Antti P. , Kiljunen Mikko 
Published: March 2023

AbstractChemical preservatives can alter stable isotope ratios in animal tissues. The effects of preservation on δ13C and δ15N values have been investigated in a variety of species, but not on δ2H values or on the freshwater pearl mussel (FPM, Margaritifera margaritifera) tissues. We evaluated the effect of ethanol preservation (unpreserved vs preserved tissues) over 6 months on the δ13C, δ15N and δ2H values of FPM foot and gonad tissues. Ethanol preservation significantly increased δ13C values (foot 0.4 ‰; gonad 0.3 ‰), whereas it did not significantly affect δ15N values (foot 0.2 ‰; gonad − 0.1 ‰). The positive effect of ethanol preservation on δ2H values (foot 7.1 ‰; gonad 14.5 ‰) and the negative effect on C:N ratios (foot  − 0.1; gonad − 0.5) depended on the tissue type, with larger effects found on the lipid-rich gonad. Overall, ethanol preservation affected δ2H values more than the δ13C, δ15N or C:N ratios of FPM tissues. After 1 month of preservation, the isotope values remained rather stable, and significant changes were only observed in δ15N values. The results imply that ethanol-preserved FPM samples can be used if potential shifts in isotopic and elemental ratios are accounted for prior running mixing models for estimating dietary proportions.
New Far-Infrared Laser Frequencies Generated by CH3CN, CD3CN, $^{13}\textit {CH}_{3}$I, CD3I, and $^{13}\textit {CD}_{3}$I
Authors: Jackson Michael 
Published: March 2023

AbstractHeterodyne techniques have been used to experimentally determine, for the first time, the frequencies for nineteen laser emissions ranging from 264 to 984 GHz. These laser emissions were generated by optically pumping either CH3CN, CD3CN, $^{13}\textit {CH}_{3}$

13

CH

3

I, CD3I, or $^{13}\textit {CD}_{3}$

13

CD

3

I with a CO2 laser. This includes the newly discovered 566.325-μ m laser emission from optically pumped $^{13}\textit {CD}_{3}$

13

CD

3

I. The fractional uncertainties with which these frequencies were experimentally determined, up to ± 5 × 10− 7, were of sufficient accuracy to confirm or revise seven previously proposed far-infrared laser assignments.
Economic Evaluation of Inpatient Multimodal Occupational Rehabilitation vs. Outpatient Acceptance and Commitment Therapy for Sick-Listed Workers with Musculoskeletal- or Common Mental Disorders
Authors: Aasdahl Lene , Fimland Marius Steiro , Bjørnelv Gudrun M.W , Gismervik Sigmund Østgård , Johnsen Roar , Vasseljen Ottar , Halsteinli Vidar 
Published: March 2023

AbstractPurpose: To evaluate the cost-effectiveness and cost-benefit of inpatient multimodal occupational rehabilitation (I-MORE) compared to outpatient acceptance and commitment therapy (O-ACT) for individuals sick listed due to musculoskeletal- or common mental disorders during two-years of follow-up. Methods: We conducted an economic evaluation with a societal perspective alongside a randomized controlled trial with 24 months follow-up. Individuals sick listed 2 to 12 months were randomized to I-MORE (n = 85) or O-ACT (n = 79). The outcome was number of working days. Healthcare use and sick leave data were obtained by registry data. Results: Total healthcare costs during the 24 months was 12,057 euros (95% CI 9,181 to 14,933) higher for I-MORE compared to O-ACT, while the difference in production loss was 14,725 euros (95% CI -1,925 to 31,375) in favour of I-MORE. A difference of 43 (95% CI -6 to 92) workdays, in favour of I-MORE, gave an incremental cost-effectiveness ratio of 278 euros for one workday, less than the cost of one day production (339 euros). Net societal benefit was 2,667 euros during two years of follow-up. Conclusion: Despite considerable intervention costs, the lower production loss resulted in I-MORE being cost-effective when compared to O-ACT. Based on economic arguments, I-MORE should be implemented as a treatment alternative for individuals on long-term sick leave. However, more research on subgroup effects and further follow-up of participants’ permanent disability pension awards are warranted.
The association between renal hyperfiltration and mortality is not mediated by diabetes mellitus
Authors: Ould Setti Mounir , Voutilainen Ari , Niskanen Leo , Tuomainen Tomi-Pekka 
Published: March 2023

Abstract
Background
Renal hyperfiltration (RHF), recently established as a risk factor for mortality, is linked to current and subsequent diabetes mellitus (DM). DM could be seen as a mediator in the pathway between RHF and mortality. However, the mediating role of DM in the relationship between RHF and mortality is unclear.

Methods and results
Based on a cohort of 2682 Finnish men from the Kuopio Ischaemic Heart Disease Risk Factor Study (KIHD) followed-up for 35 years, we evaluated the association between RHF and mortality, with DM as a mediator, following two methods: a classic mediation analysis approach, using Cox regression, and a counterfactual framework for mediation analysis, using g-computation, Cox regression, and logistic regression. RHF is associated with an increased risk of mortality. This association was not mediated by DM. Under a counterfactual framework and on a hazard ratio scale, RHF association with mortality had a total effect of 1.54 (95% confidence interval, 1.26–1.98) and a controlled direct effect of 1.66 (1.34–2.16).

Conclusion
An association between RHF and mortality risk, independent of DM, was established. RHF should be considered, managed, and followed-up as a mortality-associated condition, regardless of the status of DM. We suggest clinicians to consider including RHF screening in routine clinical care, especially diabetic care.
Coccoloba-associated xerocomoid boletes (Boletaceae) from the Caribbean and Mexico: Tropicoboletus ruborculus gen. et comb. nov., revision of Xerocomus coccolobae, phylogenetic assessment of Singerocomus guadelupae comb. nov., and type studies of Xerocomus caeruleonigrescens, X. cuneipes, and X. pseudoboletinus var. pini-caribaeae
Authors: Gelardi Matteo , Angelini Claudio , Biketova Alona Yu. , Suz Laura M. , Ercole Enrico , Svetasheva Tatiana Yu. , Miller Kurt O. , de la Fuente Javier Isaac , Jiménez Jesús García , Vizzini Alfredo 
Published: March 2023

Abstract
Only two Coccoloba-associated xerocomoid boletes with smooth basidiospores are currently known from the Dominican Republic, namely Boletus ruborculus and Xerocomus coccolobae. A multilocus phylogenetic analysis of four gene markers (ITS, LSU, RPB2, TEF1) reveals that B. ruborculus forms an autonomous clade in the Boletaceae corresponding to a novel genus, which is introduced here as Tropicoboletus gen. nov., whereas X. coccolobae is confirmed as a member of Xerocomus s. str. Tropicoboletus is sister to subfamily Xerocomoideae in the combined RPB2/TEF1 Boletaceae-wide analysis. Accurate morphological descriptions of the two species based on well-annotated samples are provided, accompanied by color photographs of fresh specimens in habitat and line drawings of their main anatomical features. The holotype collections of B. ruborculus and X. coccolobae were successfully sequenced and re-examined anatomically. The distribution range of Tropicoboletus ruborculus comb. nov. is extended from the original locality in Puerto Rico to the Dominican Republic and Mexico where its presence is reported for the first time. Similarly, the Dominican collections of X. coccolobae represent the first documented occurrence of this species for the Island of Hispaniola. Based on molecular and morphological evidence, we conclude that the Belizean species Xerocomus olivaceus is conspecific with X. coccolobae and is therefore reduced into synonymy. In addition, the holotypes of Xerocomus caeruleonigrescens, Xerocomus cuneipes, and Xerocomus pseudoboletinus var. pini-caribaeae were microscopically re-studied, although their exact taxonomic placement remains unresolved in the absence of any phylogenetic inference. Molecular investigation of a paratype of Boletus guadelupae resulted in a conspecificity with the recently described Singerocomus atlanticus from Brazil, extending the biogeographic coverage of Singerocomus to the Caribbean. Accordingly, the new combination Singerocomus guadelupae is proposed and S. atlanticus is synonymized. Finally, a putative novel Xerocomus s. str. species is discovered from the Dominican Republic but not formally described for the time being due to the paucity of material available.
The more things change, the more they stay the same: promises of bioeconomy and the economy of promises
Authors: Eversberg Dennis , Koch Philip , Lehmann Rosa , Saltelli Andrea , Ramcilovic-Suominen Sabaheta , Kovacic Zora 
Published: March 2023

AbstractThis editorial lays out the core themes of the special feature and provides an overview of the contributions. It introduces the main argument, namely that the promises of far-reaching change made by recent bioeconomy policies are in fact strategically directed at avoiding transformative change to existing societal arrangements. Bioeconomy discourse showcases technological solutions purported to solve sustainability ‘problems’ while sustaining economic growth, but avoids issues of scalability, integration or negative consequences. Thus, bioeconomy policies, and particularly the latest versions of the predominantly European ‘bio-resource’ variety that have rhetorically integrated a lot of previous sustainability-minded criticism, serve to ward off or delay challenges to an unsustainable status quo, in effect prolongating the escalatory imperatives of capitalist modernity that are at the root of current crises. The editorial’s second part highlights the contributions that the 13 featured articles, based on theoretical considerations as well as policy analyses and empirical case studies from a range of countries, make to this argument.
Thin Hybrid Hemp/Carbon Fiber Composites: Manufacturing, Flexural, and Impact Behavior
Authors: Boccarusso Luca , Pinto Fulvio , Myronidis Kostas , De Fazio Dario , Durante Massimo 
Published: March 2023

AbstractThis work is focused on the manufacturing and mechanical characterization of hybrid thin laminates in which the reinforcement is a combination of woven carbon and hemp fibers. Two types of hemp fabrics that differ in areal density were adopted for the production of the hybrid samples in sandwich configuration (1.8 mm in thickness), and pure carbon laminates were fabricated as reference. An ad-hoc manufacturing process was presented, and low-velocity impacts (at 2 and 5 J) and flexural tests were carried out. The results proved that, depending on the required performance, two carbon plies can be replaced by one hemp ply without affecting the performance of the structure while at the same time enhancing its sustainability.
A New Approach to the Optimization of the Austenite Stability of Metastable Austenitic Stainless Steels
Authors: Berger Aaron , Egels Gero , Fussik Robert , Benito Santiago Manuel , Weber Sebastian 
Published: March 2023

AbstractAustenitic steels used for components in high-pressure hydrogen storage systems in the automotive sector have to meet high requirements in terms of material properties and cost efficiency. The commonly used 1.4435/AISI 316L type steels fulfil the technological requirements but are comparatively expensive and resource-intensive. Lower alloyed steel grades are less costly, though prone to α-martensite formation and therefore sensitive to hydrogen embrittlement. Segregation-related fluctuations of the local element concentrations exert a strong impact on the austenite stability, thus controlling the segregation behavior can improve the austenite stability of lean alloyed steel grades, making them suitable for hydrogen applications. In this work, a novel approach for the optimization of alloy compositions with the aim of improving the homogeneity of the austenite stability is developed. The approach is based on combining automated Scheil–Gulliver solidification simulations with a multi-objective optimization algorithm. The solidification simulations provide information about the influence of the segregation profiles on the local austenite stability, which are then used to optimize the alloy composition automatically. The approach is exemplarily used for an optimization within the compositional range of 1.4307/AISI 304L. It is shown that a significant increase in the homogeneity of the austenite stability can be achieved solely by adjusting the global element concentrations, which has been validated experimentally.
Graphical Abstract
Introducing the THz time domain CT system for evaluating kernel weight and plumpness of sunflower seed
Authors: Lei Tong , Sun Da-Wen 
Published: March 2023

AbstractThe Terahertz (THz) time domain computed tomography (CT) system was used for evaluating kernel weight and plumpness of sunflower seed in present study. Specifically, a series of THz projections of the sunflower seed on a rotation stage were captured by a customized transmission mode THz time domain imaging system from different angles. These projections were preprocessed and then modelled by the inverse Radon transform to reconstruct the three-dimensional (3D) sunflower seed. The shapes and structures of sunflower seeds in reconstructed volumetric images were well presented. The volume ratio (obtained by THz CT imaging) and the area ratio (obtained by RGB imaging) of the whole seed to the kernel were calculated as 3D and 2D plumpness, respectively. The comparison between these two different plumpness indicating that our 3D plumpness can better describe the sunflower seed structure. Correlation coefficient (R) between sum intensity values of kernel voxels and kernel weights is 0.89 at 1.2 THz. This is the first application of applying THz CT systems to agri-food research, and the results indicate that THz time domain CT can be a useful nondestructive tool for evaluating weight and plumpness of intact sunflower seed. In addition, there is potential to extend the THz time domain CT system to the analysis of other agri-food sample types.
Effect of limiting current density on corrosion performance of Ni–Mo, Ni–Cd and Ni–Mo–Cd alloy coatings
Authors: Shetty Akshatha R. , Hegde A. Chitharanjan 
Published: March 2023

AbstractIn this article an attempt was made to increase the corrosion resistance of Ni– Mo alloy coatings with the addition of small quantity of CdCl2 into its bath. The limiting of limiting current density (iL) of Ni in both Ni–Mo and Ni–Cd baths due to inherent induced and normal type of codeposition has been successfully alleviated by addition of 1 g/L of CdCl2.The advent of induced and normal type of codeposition of individual binary baths has been used to optimize the Ni content of the ternary deposit for better corrosion stability. The composition vs. current density plots of all coatings have been studied, and thereby optimaliL of Ni in all baths were assessed. The content of Mo was found to be decreased with the small addition of Cd to the bath. Results revealed that (Ni–Mo–Cd)6.0 Adm−2 coating showed better corrosion resistance by reducingiL of Ni, on addition of Cd+2 ions into the bath and was explained in the light of diffusion limited deposition of Ni+2 ions. The results were supported by SEM (scanning electron microscopy), XRD (X-ray diffraction) and AFM (atomic force microscopy) study of Ni–Mo, Ni–Cd and Ni–Mo–Cd coatings at optimal current densities.