bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of Suspected Achromatopsia by Multimodal Diagnostic Testing
Authors: Kugler Sylvia A. , Valmaggia Christophe , Sturm Veit , Schorderet Daniel F. , Todorova Margarita G. 
Published: September 2023

Abstract
Background Achromatopsia (ACHM) as a hereditary cone disease might manifest in a stationary and progressive manner. The proper clinical and genetic diagnosis may allow an individual
prognosis, accurate genetic counselling, and the optimal choice of low vision aids. The primary aim of the study was to determine the spectrum of clinical and genetic diagnostics required to
characterize the ACHM.
Methods A retrospective analysis was performed in 8 patients from non-related families (5 ♀,3 ♂); age at diagnosis: 3 – 56 y, mean 18.13 (SD ± 18.22). Clinical phenotyping, supported
by colour vision test, fundus photography-, autofluorescence- (FAF), infra-red- (IR), OCT imaging and electroretinography provided information on the current status and the course of the
disease over the years. In addition, genetic examinations were performed with ACHM relevant testing (CNGA3, CNGB3, GNAT2, PDE6C, PDE6H and the transcription factor ATF6).
Results All patients suffered photophobia and reduced visual acuity (mean: 0.16 [SD ± 0.08]). Nystagmus was identified in 7 from 8 subjects and in one patient a head-turn right
helped to reduce the nystagmus amplitude. Colour vision testing confirmed complete achromatopsia in 7 out of 8 patients. Electrophysiology found severely reduced photopic- but also scotopic
responses. Thinning and interruption of the inner segment ellipsoid (ISe) line within the macula but also FAF- and IR abnormalities in the fovea and/or parafovea were characteristic in all
ACHM patients. Identification of pathogenic mutations in 7 patients helped to confirm the diagnosis of ACHM (3 adults, 4 children; 3 ♀ and 4 ♂). Achromatopsia was linked to CNGA3 (2
♀, 1 ♂) and CNGB3 variants (2 ♀, 3 ♂). The youngest patient (♀, 10 y) had 3 different CNGB3 variants on different alleles. In a patient (♂, 29 y) carrying 2 pathogenic
digenic-triallelic CNGA3- and CNGB3-mutations, a severe progression of ISe discontinuity to coloboma-like macular atrophy was observed during the 12-year follow-up. The oldest
female (67 y) showed a compound homozygous CNGA3- and heterozygous CNGB3-, as well as a heterozygous GUCY2D variants. The destruction of her ISe line was significantly
enlarged and represented a progressive cone-rod phenotype in comparison to other ACHM patients. In a patient (♂, 45 y) carrying a pathogenic CNGB3 and USH2 mutation, a severe
macular oedema and a rod-cone phenotype was observed. In addition, two variants in C2ORF71 considered as VOS were found. One patient showed the rare ATF6 mutation, where a
severe coloboma-like macular atrophy was observed on the left eye as early as at the age of three years.
Conclusion Combining multimodal ophthalmological diagnostics and molecular genetics when evaluating patients with ACHM helps in characterizing the disease and associated modifiers,
and is therefore strongly recommended for such patients.
Primary Intracranial Extraskeletal Mesenchymal Chondrosarcoma of the Brain in a Pediatric Patient: A Case Report and Review of Literature
Authors: Sikdar Debanjan , Gupta Sweety , Roshan Ravi , Agarwal Shruti , Joseph Deepa M. , Gupta Manoj 
Published: September 2023

AbstractIntracranial extraskeletal mesenchymal chondrosarcoma, which is characterized by undifferentiated mesenchymal cells in the presence of occasional pockets of mature hyaline cartilage, is rare in our clinical practice and commonly seen in young adults. In the pediatric population, only a few cases have been reported. In this article, we describe a case of primary recurrent intracranial mesenchymal chondrosarcoma in an 11-year-old boy well treated by surgery, radiation, and chemotherapy. We also reviewed all previously published reports on pediatric patients on the basis of their manifestations and management.
Pulmonary Hypertension Associated with Left Heart Disease
Authors: Baratto Claudia , Caravita Sergio , Vachiéry Jean-Luc 
Published: September 2023

AbstractPulmonary hypertension (PH) is a common complication of diseases affecting the left heart, mostly found in patients suffering from heart failure, with or without preserved left ventricular ejection fraction. Initially driven by a passive increase in left atrial pressure (postcapillary PH), several mechanisms may lead in a subset of patient to significant structural changes of the pulmonary vessels or a precapillary component. In addition, the right ventricle may be independently affected, which results in right ventricular to pulmonary artery uncoupling and right ventricular failure, all being associated with a worse outcome. The differential diagnosis of PH associated with left heart disease versus pulmonary arterial hypertension (PAH) is especially challenging in patients with cardiovascular comorbidities and/or heart failure with preserved ejection fraction (HFpEF). A stepwise approach to diagnosis is proposed, starting with a proper clinical multidimensional phenotyping to identify patients in whom hemodynamic confirmation is deemed necessary. Provocative testing (exercise testing, fluid loading, or simple leg raising) is useful in the cath laboratory to identify patients with abnormal response who are more likely to suffer from HFpEF. In contrast with group 1 PH, management of PH associated with left heart disease must focus on the treatment of the underlying condition. Some PAH-approved targets have been unsuccessfully tried in clinical studies in a heterogeneous group of patients, some even leading to an increase in adverse events. There is currently no approved therapy for PH associated with left heart disease.
A New Technique To Enhance Levator Power in Congenital Ptosis
Authors: Nandi Dr. Mrinmay 
Published: September 2023

AbstractSevere degree of congenital Ptosis, not correctable by resection of levator alone poses a formidable challenge. Results with classical technique of brow suspension with frontalis sling, leaves much to be desired. Improved version of this technique is tried on seven patients and appears to be superior.
Complicated Membranous Urethro-anal Fistual Treated With Staged Scrotal Flap urethroplasty
Authors: Marya Dr. S.K.S. , Yadav Dr. S.P. , Gupta Dr. Ashok K. 
Published: September 2023

AbstractA rare case of inatrogenic membranous urethroanal fistula is reported. The fistula was associated with stricture urethra and scarred anal sphincter. The anourethral fistula and stricture urethra were treated simultaneously by staged scrotal flap urethroplasty without disturbing the anal sphincter.
Associated Anomalies With Those Of The Hands
Authors: Tripathi Prof. F.M. , Atam Dr. R. , Rai Dr. A.K. , Gupta Prof. S.K. 
Published: September 2023

AbstractThe present study is based on the observations of associated anomalies with those of the 50 cases of congenital hand anomalies. 15 cases had associated anomalies of feet and 4 had anomalies of the other parts of the body like face and genito urinary tract.
Malignant Schwannoma of Mandible - Case Report
Authors: Nabirasool M , Babu V Surendra , Reddy D Venkata Raghava 
Published: September 2023

SummaryA case of malignant schwannoma of the mandible in a forty year old female is presented because of its rarity at that site. The clinical features, histopathology and management is presented and the relevant literature is reviewed.
Role of Vitamin E in Ischaemic Skin Flap Survival in Rats
Authors: Khazanchi Rakesh K , Pal Sujoy , Mital Deepak , Gupta Kalpana , Guleria Sandeep , Nanda Vipul 
Published: September 2023

SummaryThe efficacy of free radical scavenger – Vitamin E (VE) in salvage of ischaemic skin flaps was studied in an experimental rat skin flap model. The animals were divided into two groups – a control group (N=15) who did of receive VE and a test group (N=15) who received VE starting one week preoperatively. No significant difference was found in flap necrosis between the control group (38.365% ± 1.398% SEM) and the test group (35.288% ± 0.635% SEM), which received therapeutic dose of VE (100 mg/kg/day. 1 mg = 1.49 I.U). Further research is needed to establish the role of vitamin E as an agent of ischaemic skin flap salvage.
Reconstruction Of Thumb By Distraction - A Case Report
Authors: Sharma Dr. P.K. , Verma Dr. K.K. , Sharma Dr. O.P. , Malhotra Dr. A. 
Published: September 2023

AbstractA simple, excellent, practical & effective method of Reconstruction of thumb is described in this distraction technique. Reconstructed thumb is of near normal, colour, texture, sensation, stability, aesthetics, and function wise.
Burns In Elderly Patients
Authors: Banerjee Dr. Chhanda , Mazumdar Dr. Biman 
Published: September 2023

AbstractIn 60 years old or above, 35% total body surface area burns prove fatal.In patients of less than 35% T.B.S., aggressive excisions and free grafts also prove a disaster. Elderly in authors opinion should not receive highly specialized care in isolation ward and should be allowed to remain in company of their relations throughout the period of treatment.
Modified Incision For Orbicularis Oris Function Conservation In Intra Oral Lesions
Authors: Sen Dr. Mira , Dasgupta Dr. Asit Ranjan , Chatterjee Dr. Meera , Chatterjee Dr. Dipankar , Vani Dr. N. , Bhowmik Dr. Amit 
Published: September 2023

AbstractA new incision with a view to reduce vascular compromise, to have a better control of saliva, speech and mastication, in oral cancer surgery is described.
Gluteal Thigh Flap Coverage In Pressure Sores
Authors: Uppal Dr. Sanjeev , Singh Dr. Gurpartap , Mander Dr. Karamjit S. , Singh Dr. Avtar , Pasricha Dr. Puneet , Bath Dr. J.S. 
Published: September 2023

AbstractSingle stage successful and easy closure of Ischial and trochantric pressure sores is now possible with use of a gluteal thigh flap. Experience of six cases, so treated is presented.
Gluteal Fascio-cutaneous Flap For Reconstruction Of Lower Leg Defects
Authors: Khan Dr. Masood H. , Khan Dr. Arshad Hafeez , Yaseen Dr. M. , Bhat Dr. F.A. 
Published: September 2023

AbstractReconstruction of full thickness defects of lower leg by ipsilateral inferior gluteal fasciocutaneous flap is presented. This flap is based on the decending branch of the inferior gluteal artery.
Chin Augumentation In Temporoman-Dibular Ankylosis
Authors: Sinha Dr. J.K. , Mangal Dr. K.K. 
Published: September 2023

AbstractIn T.M. Joint ankylosis cases post operatively, normal facial contour and profile cannot be achieved although trismus is relieved. Development of mandible and facial skeleton by puberty exaggerate this problem. Not only is there chin retrusion, wide lip separation, there are also problems related to obliquely placd protruding upper and lower incisor and canines, in need of further treatment. Chin augumentation at puberty by sialistic implant, to bring about normal chin appearance and face profile is discussed.
Reconstruction Of Lower Lip By Neurovascular Fan Flap
Authors: Khan Dr. Masood H. , Khan Dr. Arshad H. , Yaseen Dr. M. 
Published: September 2023

SummaryFull thickness excisional defects of upper and lower lips are normally reconstructed by local tissues such as remaining lip segment. And adjacent check tissues, whenever possible or by regional or distant flaps when defects are large.Disadvantages inherited in all these flaps are loss of continuity of oral sphincter because of interruption of orbiculari oris muscle continuity and aesthetical unsatisfactory results. In present case a technique is used where above factors are overcome.
Use Of Extended Deep Inferior Epigastric Artery Flap In Management Of Groin Wounds With Exposed Vessels
Authors: Sharma Dr. Ramesh Kumar 
Published: September 2023

AbstractConsistency, safety, ease and least morbidity of donor site are some of the factors which have made extended inferior epigastric artery based flap popular. For major reconstruction in groin region where important structures are exposed, its use in demonstrated in eight cases.
Abjection in sports: An ethical approach
Authors: Jönsson Kutte 
Published: September 2023

AbstractIn her essay Powers of Horror, Julia Kristeva investigates the concept of abjection. Essentially, the term means “the state of being cast off” and according to Kristeva it is a feeling of disgust, filth and humiliation, things we tend to reject for becoming subjects and protecting identities. But as I will argue here, by rejecting athletes who dissolve the culturally strict boundaries in sports, the sports organizations become abjects themselves, and consequently evade moral responsibility.
The Spanish subjunctive and grounding
Authors: Kratochvílová Dana 
Published: September 2023

Abstract
The paper offers a cognitively oriented approach to the Spanish subjunctive. This verb form is examined in light
of Langacker’s grounding theory. In my understanding, the ground is defined as the communication situation with three inherently
interrelated components: temporality, modality and evidentiality. The subjunctive is then analysed in relation to these three
categories. Particular attention is paid to the evidential component of the ground and its relationship to the Spanish
subjunctive. I define the contexts in which the subjunctive appears as grounding inhibitors. Consequently, the subjunctive is
understood as a verb form lacking temporal, modal and evidential grounding (in opposition to the indicative, which denotes fully
grounded processes).
A 1-bit phase reconfigurable fixed-frequency wide-angle steering leaky-wave antenna
Authors: Han Jian-Qiao , Meng Fan-Yi , Wang Xiaolong , Liu Yu-Hang , Ding Chang , Jin Tao , Huang Guanlong , Xu Shanshan , Lv Bo , Wu Qun 
Published: September 2023

Abstract
A 1-bit phase reconfigurable fixed-frequency beam steering leaky-wave antenna (FBSLWA) with wide-angle steering is proposed in this paper. By controlling two p–i–n diodes on the branches of the element, a stable 180° phase difference is realized. Moreover, the open stop-band effect at the broadside radiation is suppressed by reducing the reflection coefficients of the element. The proposed FBSLWA can achieve wide-angle steering within a frequency bandwidth of 10.4 GHz–11.8 GHz. As for the measured results, they show that the achievable beam steering ranges of the FBSLWA at 10.4 GHz, 11.0 GHz, and 11.8 GHz are −61° to +59°, −64° to +71°, and −62° to +58° respectively, with measured peak gains of 12.1 dBi, 13.9 dBi, and 11.7 dBi.
Prediction of tribology in (Mg2Si+TiB2)/A356 composites based on RSM method and correlative with topographical characteristics
Authors: Yadav Amit Kumar , Gautam Gaurav , Mohan Sunil 
Published: September 2023

Abstract
This work deals with the prediction of tribological performance in (Mg2Si+TiB2)/A356 composites. In this work, tribological properties are also correlated with topographical characteristics. The effect of several input factors such as load, sliding distance and TiB2 wt% on tribological characteristics of (Mg2Si+TiB2)/A356 composites was explored by Response Surface Methodology (RSM). Central composite design (CCD) with three input factors and three levels of variables in RSM was used to develop a statistical model. RSM suggests a quadratic model to express a mathematical relationship between input factors to assess wear rate and coefficient of friction (COF). Analysis of variance (ANOVA) was applied to investigate the influence of input factors on wear rate and COF and found that most significant variable that influences wear rate and COF is applied load followed by TiB2 wt% and sliding distance. The desirability function approach is applied to optimized input variables to minimize wear rate and COF. Optimum wear rate is noticed at input variables of 26 N load, 2766 m sliding distance and 3.36 wt% of TiB2 and optimum COF was observed at 29 N of load, 2233 m sliding distance and 1 wt% of TiB2. A confirmatory test was conducted to validate the developed model and observed that experimental results matched the predicted value with an error of less than 5%. SEM and AFM examined surface topography of wear surfaces to understand the wear mechanism and surface features at various input factors. Microstructural features were also examined under optical microscope and SEM, revealing that increased TiB2 content in hybrid composite refined primary Mg2Si and eutectic Mg2Si phase and resulted in increased hardness and improved tribological behaviour of hybrid composite.
The kernel-balanced equation for deep neural networks
Authors: Nakazato Kenichi 
Published: September 2023

Abstract
Deep neural networks have shown many fruitful applications in this decade. A network can get the generalized function through training with a finite dataset. The degree of generalization is a realization of the proximity scale in the data space. Specifically, the scale is not clear if the dataset is complicated. Here we consider a network for the distribution estimation of the dataset. We show the estimation is unstable and the instability depends on the data density and training duration. We derive the kernel-balanced equation, which gives a short phenomenological description of the solution. The equation tells us the reason for the instability and the mechanism of the scale. The network outputs a local average of the dataset as a prediction and the scale of averaging is determined along the equation. The scale gradually decreases along training and finally results in instability in our case.
Simultaneous realization of FIR-based multimode optical thermometry and photonic molecular logic gates in Er3+ and Yb3+ co-doped SrTiO3 phosphor
Authors: Kumar Ishant , Kumar Avinash , Kumar Sandeep , Nair Govind B , Swart H C , Gathania Arvind K 
Published: September 2023

Abstract
Er3+ and Yb3+ co-doped SrTiO3 phosphors were synthesized and characterized by using the x-ray powder diffraction method, field emission scanning electron microscopy, and photoluminescence spectroscopy. The samples were subjected to thorough luminescence analysis. Under 980 nm infrared (IR) excitation, the (2H11/2,4S3/2) → 4I15/2 and 4F9/2 → 4I15/2 transitions of Er3+ gave green and red emissions, respectively. The up-conversion mechanism of the synthesized phosphor was studied using the power-dependent emission spectra of the SrTiO3:Yb3+, Er3+ phosphor. A rate equation model for the up-conversion mechanism of SrTiO3:Yb3+, Er3+ has been proposed. The temperature-dependent responses of various thermal and non-thermally coupled emission lines of Er3+ ions were used to elaborate the thermal sensing capabilities of the synthesized phosphor. The fluorescence intensity ratio technique was used for the temperature sensing measurements. Sensing measurements were performed in the temperature range of 303 to 618 K. Relative sensitivities of 1.28% K−1, 0.15% K−1, 0.98% K−1, and 0.15% K−1 were observed using various thermally and non-thermally coupled energy levels. Furthermore, using heat and incident IR excitation as physical inputs, we have shown that the synthesized phosphor can also be used to design various elementary logic gates such as AND, INHIBIT, and DEMULTIPLEX photonic molecular logic gates. A high switching ratio of ∼143% for the AND gate and ∼44.8% for the INHIBIT gate was observed using the scheme presented in this manuscript. The synthesized phosphor has the potential to be used as a bifunctional material for optical thermometry and molecular logic devices.
Linear superposition for a novel nonlocal PT -symmetric mKdV-sG system
Authors: Jia Man , Lou S Y 
Published: September 2023

Abstract
A novel nonlocal




-symmetric modified Korteweg–de Vries-sine Gordon (mKdV-sG) system is established via the consistent correlated bang (CCB) method from the normal mKdV-sG equation. The obtained nonlocal mKdV-sG system is Lax integrable and can be reduced to the normal mKdV-sG equation with suitable function selections. Using symmetry-antisymmetry separation method, a linear superposition solution theorem for the nonlocal mKdV-sG system is concluded. Abundant nonlinear wave structures of the obtained nonlocal system, such as the periodic waves, the kinks, the breathers and periodic-periodic interaction waves, periodic-kink interaction waves, periodic-breathers interaction waves solutions are obtained from the linear superposition solution theorem.
Germanium-based nearly hyperuniform nanoarchitectures by ion beam impact
Authors: Claude Jean-Benoit , Bouabdellaoui Mohammed , Khoury Mario , Wenger Jerome , Bollani Monica , Salvalaglio Marco , Abbarchi Marco 
Published: September 2023

Abstract
We address the fabrication of nano-architectures by impacting thin layers of amorphous Ge deposited on SiO2 with a Ga+ ion beam and investigate the structural and optical properties of the resulting patterns. By adjusting beam current and scanning parameters, different classes of nano-architectures can be formed, from elongated and periodic structures to disordered ones with a footprint of a few tens of nm. The latter disordered case features a significant suppression of large length scale fluctuations that are conventionally observed in ordered systems and exhibits a nearly hyperuniform character, as shown by the analysis of the spectral density at small wave vectors. It deviates from conventional random fields as accounted for by the analysis of Minkowski functionals. A proof of concept for potential applications is given by showing peculiar reflection properties of the resulting nano-structured films that exhibit colorization and enhanced light absorption with respect to the flat Ge layer counterpart (up to one order of magnitude at some wavelength). This fabrication method for disordered hyperuniform structures does not depend on the beam size. Being ion beam technology widely adopted in semiconductor foundries over 200 mm wafers, our work provides a viable pathway for obtaining disordered, nearly-hyperuniform materials by self-assembly with a footprint of tens of nanometers for electronic and photonic devices, energy storage and sensing.
3D permanent magnetic lattices for ultracold atoms
Authors: Ghanbari Saeed 
Published: September 2023

Abstract
We introduce 3D permanent magnetic lattices for ultracold atoms which can be created by arbitrary number of 2D arrays of square permanent magnetic slabs plus a bias magnetic field. Instead of the square magnets, we can also use magnetic films with square holes. We find analytical expressions for the location of the nonzero magnetic field minima and physical quantities such as trap depths, absolute value of the magnetic field and curvatures as well as trap frequencies at each minimum. We show that most of them, including the trap depths, modulation depths, and trap frequencies can be controlled by the bias field. Accessible trap depths and trap frequencies in the permanent magnetic lattices are much higher compared to the optical lattices. Between the magnetic layers, the trap frequencies are higher compared to above the top layer (under the bottom layer). In principle, our method can be generalized to other 2D permanent magnetic lattices and we show how to transform a 2D lattice of a given geometry into 3D by using multiple layers of magnets.
Continuous limit of a tight-binding model on a hexagonal disk in a magnetic field: size dependence on energy level
Authors: Inui Norio 
Published: September 2023

Abstract
This study considers the energy level of a charged particle on a large hexagonal lattice in a magnetic field. The discretized Schrödinger equation on a hexagonal lattice, which can be expressed as a special case of a tight-binding model is derived, and its energy level is numerically calculated. The size dependence of the energy level near zero for large radii is considered by analyzing the asymptotic behavior of the zeros of the Laguerre function, which is the radical wavefunction of the continuous Schrödinger equation. Additionally, the splitting of the Landau level due to the finite size of a hexagonal disk is discussed.