bluuebunny/crossref_metadata_2025_split huggingface dataset:
Advanced oxidation protein products levels and Paraoxonase 1(Arylesterase) activity in patients with thyrodisim
Authors: Abdul Latif Jouad Hadeel , AL- Shammaree Shatha Abdul Wadood 
Published: March 2023

Objectives: The purpose of study was to explore the correlation of advanced oxidation protein products (AOPP), which reflect the oxidation of protein and the oxidative stress status, and the activity of antioxidant enzyme of Paraoxonase (PON1), using its arylesterase activity in patients with thyrodisim.
Methods: The study included 100 women with newly diagnosed thyrodisim were subdivided in two groups according to thyroid hormones levels: hyperthyroidism group (50 female patients, age range 18-60 years); and hypothyroidism group (50 female patients, age range 18-75 years). A control group (30 healthy females, age range 18–70 years) was also included for comparison. Demographic and clinical measurements for all participants were recorded which include: Body mass index (BMI), age, weight, height, lipid profile, vitamin D, thyroid hormones (TSH, T3, and T4, FT3, FT4), AOPP levels, and arylesterase activity.
Results: The serum level of AOPP in hypothyroidism group (71.92±19.04 μmol/L) and in hyperthyroidism group (30.41±4.72 μmol/L) were significantly higher than controls (13.12±2.50 μmol/L) (P<0.05). In contrast, lower aryl esterase activity was found in hypothyroidism (5.03±0.50 U/L), and hyperthyroidism (3.64±0.40 U/L) when compared to control group (6.78±0.62 Ku/L) with significant values (P< 0.05).
Conclusions: these results disclosed a significant role of protein oxidation in patients with hypothyroidism as well as the oxidative stress status.
Reliability and validity of Knee Injury and Osteoarthritis Outcome Score (KOOS) in Iranian Population
Authors: Sabaghzadeh Amir , Aslani Hamidreza , Shakeri Jousheghan Saman , Aslani MohammadAmin , Tajik Katayoon 
Published: March 2023

Objectives: The purpose of present study was the investigation of reliability and validity of the knee injury and osteoarthritis outcome score in the Iranian population.
Methods: The method of the present study was non-experimental and methodological. The statistical population of the present study was patients with osteoarthritis of the knee. Patients with osteoarthritis of the knee referred to the Akhtar Center were selected from 127 people by available sampling for sample adequacy. In data analysis, Cronbach's alpha test to determine internal agreement, test-retest method to determine stability in reliability, item impact method to determine face validity, CVI and CVR indicators to determine content validity, and to determine structural validity two convergent and divergent validities as well as confirmatory factor analysis were used. Results: The results showed that if the fourth question "symptoms" is removed, the questionnaire has acceptable reliability and validity.
Conclusion: The analysis of the findings indicated that the Persian version of the questionnaire (KOOS) was a reliable tool for assessing the health status and impact of various treatments on patients with osteoarthritis in the country, which had high validity and reliability.
Association between Nesfatin-1 Levels and C-Peptide in Sera of Obese / Non-Obese Type 2 Diabetic Women
Authors: Khalil Ibrahim Al-Yassiri Israa , Al-Tu’ma Fadhil Jawad , Abbood Mukheef Maher , Baqir Jawad Khosay , Abdul-Kareem Mutar Baraa 
Published: March 2023

Objective: The aim of the presented word was to assess the diagnostic accuracy of serum Nesfatin-1 in type 2 diabetes mellitus and its relationship with C-peptide level in obese and non-obese type-2 diabetic women of Iraqi population.
Methods: A case-control study was performed on 50 type 2 diabetic patients admitted in Al-Hussein Teaching Hospital and Al-Hassan center of diabetes and endocrinology unit / Kerbala health directorate – Iraq and another 50 control individuals, during the period from April, 2022 – Jan. 2023). The T2DM groups were divided into two groups 25 obese and 25 non-obese; also the control group was divided into 25 obese and 25 non-obese as apparently healthy groups. The ELISA Kit was used to measure serum Nesfatin-1 and C-peptide, and random serum glucose was measured by enzymatic colorimetric method, and lipid profile test were measured through spectrophotometric technique, instead of HbA1c% was determined using HPLC method.
Results: The results observed indicated that Nesfatin-1 levels shown a non-significant decrease in all of type 2 diabetic groups as compared with apparently healthy control group, while the C-peptide were significantly decreased in type 2 diabetic patients when compared with apparently control group. In addition, the random blood glucose and HbA1c% were shown significant elevation in type 2 diabetic patients as compared with apparently healthy control groups. The observed data indicated that Nesfatin-1 and C-peptide levels when comparing between type 2 diabetic patients and control in obese groups shown a risk factors depending upon the odd ratio observed (OR = 1.064 (1.011-1.119), 1.0200 (0.992-1.08)) respectively, but only Nesfatin-1 was shown to be significant. In BMI the levels of Nesfatin-1 and C-peptide, as shown the Nesfatin-1 was significant in obese groups, while the C-peptide as shown significant in normal weight groups. The optimal diagnostic points for Nesfatin-1 were (sensitivity = 98%, specificity = 90%) at a level (Cut-off points) = 39.13, while C-Peptide levels: (sensitivity = 98%, specificity = 94%) at a level (Cut-off points) = 15.99. Both markers have p-values of the AUC were <0.001 and statistically significant.
Conclusion: Accordingly, it was concluded that a significant relationship between circulating Nesfatin-1 levels and type 2 diabetes. Nesfatin-1 appears to be able to contribute to the treatment of obesity and diabetes because of its anorexigenic and antihyperglycemic effects. In addition, C-peptide is a known biomarker of insulin resistance and beta-cell function. High specificity and sensitivity analyzed results were obtained by ROC analysis for both markers in T2DM.
Skeletal and dentoalveolar effects of miniscrew-assisted rapid palatal expansion based on the length of the miniscrew: a randomized clinical trial
Authors: Choi Eun-Hack Andrew , Lee Kee-Joon , Choi Sung-Hwan , Jung Hwi-Dong , Ahn Hyung-Joon , Deguchi Toru , Cha Jung-Yul 
Published: March 2023

ABSTRACT

Objectives
To compare skeletal and dentoalveolar changes of miniscrew-assisted rapid palatal expansion (MARPE) according to the length of the miniscrews.

Materials and Methods
This two-arm parallel-randomized controlled trial included 32 adult patients aged 19–35 years who received orthodontic treatment with MARPE. Patients were allocated to two groups, group long (L) and short (S), through block randomization according to the length of the miniscrews installed in MARPE. Cone-beam computed tomography was performed before expansion and after removal of the MARPE; superimposition of the images was conducted. The primary outcome included the amount of bone expansion and the change in the inclination of the anchorage teeth. The secondary outcome included the success rate of midpalatal suture opening and stability of the miniscrews. Blinding was performed during outcome assessment.

Results
The final sample comprised 31 patients. There was no significant difference in patient characteristics between group L (n = 16) and group S (n = 15). The change in the width of the processus zygomaticus (P = .010) and ectocanine (P = .001) was significantly higher in group L. A significantly higher success rate of the posterior miniscrews was seen in group L (P = .024). There was no statistically significant difference in the success rate of suture separation or change in tooth inclination. Notable complications were not reported.

Conclusions
MARPE with longer miniscrews can increase the amount of expansion of the maxillary basal bone and canine alveolar bone. Although it also aided in miniscrew stability, it did not guarantee successful midpalatal suture separation.
Impact of Polymorphism in the β2-Receptor Gene on the Metabolic Response to Epinephrine After Repeated Hypoglycemia
Authors: Rokamp Kim Z. , Dela Flemming , Secher Niels H. , Grønlykke Lars , Thorsteinsson Birger , Pedersen-Bjergaard Ulrik 
Published: March 2023

The β2-receptor mediates the metabolic response to epinephrine. This study investigates the impact of the β2-receptor gene (ADRB2) polymorphism Gly16Arg on the metabolic response to epinephrine before and after repetitive hypoglycemia. Twenty-five healthy men selected according to ADRB2 genotype being homozygous for either Gly16 (GG) (n = 12) or Arg16 (AA) (n = 13) participated in 4 trial days (D1–4): D1pre and D4post with epinephrine 0.06 μg kg−1 ⋅ min−1 infusion and D2hypo1–2 and D3hypo3 with three periods of hypoglycemia by an insulin-glucose clamp. At D1pre, the insulin (mean ± SEM of area under the curve 44 ± 8 vs. 93 ± 13 pmol ⋅ L−1 h; P = 0.0051), glycerol (79 ± 12 vs. 115 ± 14 μmol ⋅ L−1 h; P = 0.041), and free fatty acid (724 ± 96 vs. 1,113 ± 140 μmol ⋅ L−1 h; P = 0.033) responses to epinephrine were decreased in AA participants compared with GG participants but without a difference in glucose response. There were no differences in response to epinephrine between genotype groups after repetitive hypoglycemia at D4post. The metabolic substrate response to epinephrine was decreased in AA participants compared with GG participants but without a difference between genotype groups after repetitive hypoglycemia.

Article Highlights
This study investigates the impact of the β2-receptor gene (ADRB2) polymorphism Gly16Arg on the metabolic response to epinephrine before and after repetitive hypoglycemia. Healthy men homozygous for either Gly16 (n = 12) or Arg16 (n = 13) participated in the study. Healthy people with the Gly16 genotype have increased metabolic response to epinephrine compared with the Arg16 genotype but without a difference between genotypes after repetitive hypoglycemia.
Acercamiento a la comprensión de textos en la resolución de problemas en matemáticas considerando los procesos inductivos y deductivos: el caso de Bobby
Authors: Benítez Pérez Alma Alicia , García Rodríguez Martha Leticia , Flores Cervantes Claudia 
Published: March 2023

La literatura en educación matemática muestra que la habilidad para resolver problemas de esa área está estrechamente relacionada con la comprensión del texto y los conocimientos previos del estudiante. Además, se ha identificado que aunque un estudiante pueda parecer experimentado en la lectura de textos variados, esto no garantiza su comprensión. Por eso, el objetivo de esta investigación fue analizar los procesos de comprensión textual en problemas matemáticos que involucran texto en un estudiante de 15 años durante un curso de álgebra de bachillerato. Para entender estos procesos se utilizaron elementos teóricos que permitieron identificar sus componentes, en particular las operaciones de segmentación y recontextualización en los procesos inductivo, deductivo y evolutivo subyacentes al fenómeno estudiado.
La metodología utilizada fue cualitativa y se empleó el método de estudio de caso. El estudiante seleccionado presentó compromiso y disponibilidad para explorar actividades que involucraron la comprensión de textos. Los instrumentos utilizados para la recolección de datos incluyeron hojas de trabajo, reportes escritos y una entrevista semiestructurada.
A partir del análisis de lo recabado se identificó que el trabajo del estudiante se caracterizó en un inicio por la exploración del contenido redaccional basado en el proceso inductivo de comprensión, del cual emergieron las unidades de texto implícitas y explícitas identificadas. En el proceso deductivo, se observó que el estudiante trabajó en relación con el significado de las fracciones como parte-todo y como índice comparativo entre dos cantidades o conjuntos de unidades. Asimismo, se destacó la importancia de entender que las fracciones son razones que permiten evidenciar la comparación.
Burnout among Employees: A Narrative Review
Authors: Kumareswaran Suriya 
Published: March 2023

In the past two decades, job burnout has rapidly become a part of everyone's lives. Employees experience burnout because of chronic job stressors. Job burnout is a prolonged response to persistent emotional and interpersonal stresses at work and is characterised by emotional exhaustion, depersonalisation, and diminishing personal accomplishment. This article explores the literature on burnout for readers to gain a better understanding of the condition. It proposes clarifying the dynamics of burnout, including the causes and consequences of its components.
L’ATTACCAMENTO SPIRITUALE AL SANTO PADRE NELLA CHIESA GRECO-CATTOLICA DI ROMANIA
Authors: RUS Anton 
Published: March 2023

Spiritual Attachment to the Holy Father Pope in Greek-Catholic Church in Romania. The present study captures the attitude of Romanian Greek Catholic believers towards the person of the Pope. This attitude is reflected in the relations that have existed over time between the Roman Pontiffs and the Greek Catholic Church on the territory of present-day Romania. On the one hand, there are various pontifical actions in favor of the Romanians united with the Church of Rome, and on the other hand, the Greek Catholic Romanians will be able to give their lives for the biblical truth of the Petrine primate.
REZUMAT: Atașamentul spiritual față de Sfântul Părinte Papa în Biserica Greco-Catolică din România. Studiul de față surprinde atitudinea credincioșilor greco-catolici români față de persoana Papei. Atitudinea respectivă se reflectă în relațiile care au existat de-a lungul istoriei între Pontifii Romani și Biserica Greco-Catolică de pe teritoriul actualii Românii. Pe de o parte, există diferite intervenții pontificale în favoarea românilor uniți cu Biserica Romei, iar pe de altă parte regăsim atitudini care determină în greco-catolicii români mărturii puternice care ating chiar nivelul sacrificiului suprem pentru adevărul biblic al primatului petrin.
Cuvinte-cheie: devoțiune, papa de la Roma, primatul petrin, Biserica Greco-Catolică din România.
Animal Trauma Triage Score, Modified Glasgow Coma Scale, age, and weight were associated with outcome in feline bite wounds (1,065 cases): a VetCOT registry study
Authors: Tinsley Ashlei T. , Oyama Mark A. , Reineke Erica L. 
Published: March 2023

Abstract

OBJECTIVE
To identify associations between admission variables, Animal Trauma Triage (ATT) score, and Modified Glasgow Coma Scale (MGCS) score with need for transfusion or surgical interventions and survival to discharge in cats with bite wounds.

ANIMALS
1,065 cats with bite wounds.

PROCEDURES
Records of cats with bite wounds were obtained from the VetCOT registry from April 2017 to June 2021. Variables included point of care laboratory values, signalment, weight, illness severity scores, and surgical intervention. Associations between admission parameters, terciles of MGCS, quantiles of ATT scores, and death or euthanasia were assessed using univariable and multivariable logistic regression analysis.

RESULTS
872 cats (82%) survived to discharge, while 170 (88%) were euthanized and 23(12%) died. In the multivariable model, age, weight, surgical treatment, ATT and MGCS scores were associated with nonsurvival. For every 1 year of age, odds of nonsurvival increased by 7% (P = .003) and for every 1 kg of body weight, odds of nonsurvival decreased by 14% (P = .005). Odds of dying increased with lower MGCS and higher ATT scores (MGCS: 104% [95% CI, 116% to 267%; P < .001]; ATT: 351% [95% CI, 321% to 632%; P < .001). Odds of dying decreased by 84% (P < .001) in cats that underwent surgery versus those that did not.

CLINICAL RELEVANCE
This multicenter study indicated association of higher ATT and lower MGCS with worse outcome. Older age increased the odds of nonsurvival, while each kilogram increase in bodyweight decreased odds of nonsurvival. To our knowledge, this study is the first to describe associations of age and weight with outcome in feline trauma patients.
Current per- and polyfluoroalkyl substance (PFAS) research points to a growing threat in animals
Authors: Brake Heather D. , Langfeldt Antonia , Kaneene John B. , Wilkins Melinda J. 
Published: March 2023

Abstract
Per- and polyfluoroalkyl substances (PFAS) are man-made chemicals that are colorless, odorless, and oil and water repellent. Their widespread use in manufacturing and industrial processes has resulted in environmental contamination found across the world. Exposure to PFAS can lead to a variety of adverse human health outcomes such as increased cholesterol, liver damage, immune suppression, and disruption of endocrine and reproductive systems. Exposure to this family of chemicals is considered a significant public health threat. Though nearly every human and animal around the world has been exposed, most of what is known regarding health effects and toxicological processes of PFAS in animals stems from human epidemiological and laboratory animal studies. Discoveries of PFAS contamination on dairy farms and concerns for companion animals have increased interest in PFAS research related to our veterinary patients. In the limited studies published to date, PFAS has been demonstrated in serum, liver, kidneys, and milk of production animals and has been linked to changes in liver enzymes, cholesterol levels, and thyroid hormones in dogs and cats. This is further addressed in the companion Currents in One Health by Brake et al, AJVR, July 2023. There is a gap in understanding the routes of exposure, absorption of PFAS, and adverse health effects among our veterinary patients. The purpose of this review is to summarize the current literature on PFAS in animals and discuss the implications for our veterinary patients.
Career stage differences in mental health symptom burden and help seeking among veterinarians during COVID-19
Authors: Russon Jody M. , Bland Krista , Ravi-Caldwell Nivedita , Haak Patricia P. , Kryda Katharyn T. , Codecá Luca , Darby Brandy J. , Bissett Carolynn J. , Murphy Julia , Hungerford Laura 
Published: March 2023

Abstract

OBJECTIVE
To explore veterinarians’ mental health symptom burden during COVID-19 and identify differences in symptom burden, social support, help seeking, and incentives and barriers associated with receiving help across career stages.

SAMPLE
Online survey responses from 266 veterinarians between June 4 and September 8, 2021.

PROCEDURES
Respondents were grouped by career stage (early [< 5 years of experience], middle [5 to 19 years of experience], or late [≥ 20 years of experience]), and results were compared across groups.

RESULTS
Of the 262 respondents who reported years of experience, 26 (9.9%) were early career, 130 (49.6%) were midcareer, and 106 (40.4%) were late career. The overall mean anxiety and depression symptom burden score was 3.85 ± 3.47 (0 to 2 = normal; 3 to 5 = mild; 6 to 8 = moderate; and 9 to 12 = severe), with 62 of 220 (28.1%) respondents reporting moderate to severe symptom burden. Most (164/206 [79.6%]) reported not accessing behavioral health providers, and of these, 53.6% (88/164) reported at least mild symptom burden. There were significant differences in both symptom burden and mental health help-seeking intentions across career stages, with early- and midcareer (vs late-career) veterinarians reporting higher symptom burden (P = .002) and midcareer (vs late-career) veterinarians reporting higher help-seeking intentions (P = .006). Barriers and incentives for seeking mental health care were identified.

CLINICAL RELEVANCE
Findings revealed differences in symptom burden and intentions to seek mental health care across veterinary career stages. Incentives and barriers identified serve to explain these career stage differences.
Evaluation of Thermophysical and Strength Properties of Composite Panels Produced from Sugarcane Bagasse and Waste Newspapers
Authors: Etuk Sunday Edet , Robert Ubong Williams , Agbasi Okechukwu Ebuka , Inyang Namdie Joseph 
Published: March 2023

Abstract
Large quantities of waste newspapers and sugarcane bagasse are prevalently discarded by open burning or indiscriminate dumping, thereby posing severe danger to the environment and public health. This study sought to examine the feasibility of managing the wastes by recycling them into value-added products for building construction. Composite panels were fabricated using waste newspaper paste (WNP) with sugarcane bagasse particles (SBP) varied at 0, 25, 50, 75, and 100 % by weight of the composite mix. Epoxy resin was thoroughly mixed with its hardener and applied as binder. The samples were developed in triplicates per proportion of the SBP adopted and then dried completely before their thermophysical and strength properties were evaluated. It was observed that variations in mean values of water absorption (28.57 – 39.43 %), thickness swelling (6.21 - 8.33 %), specific heat capacity (1232 - 1312Jkg−1K−1) trended positively with increasing proportions of the SBP. Whereas nailability remained 100.0 % in all the cases, bulk density (689.4 - 640.5 kgm−3), thermal conductivity (0.1186 - 0.1163 Wm−1K−1), thermal diffusivity (1.396 - 1.384 x 10−7 m2s−1), and flexural strength (2.572 - 2.280 N/mm2) correlated inversely with the added fractions of the SBP. Generally, it was found that the samples could perform satisfactorily if applied as ceiling or partition elements in building design. Therefore, recycling of sugarcane bagasse and waste newspapers as described in this study could serve as a promising way of solving their disposal problems and also enhance achievement of low-cost and safe buildings.
Numerical Failure Analysis of Laminated Beams Using a Refined Finite Element Model
Authors: Layachi Maroua , Khechai Abdelhak , Ghrieb Abderrahmane , Layachi Safa 
Published: March 2023

AbstractIn the present investigation, laminated composite beams subjected to a bending static loading are studied in order to determine their failure mechanisms and the first ply failure (FPF) load. The FPF analysis is performed using a refined rectangular plate element. The present element is formulated based on the classical lamination theory (CLT) to calculate the in-plane stresses. To achieve this goal, several failure criterions, including Tsai-Wu, Tsai-Hill, Hashin, and Maximum Stress criteria, are used to predict failure mechanisms. These criterions are implemented within the finite element code to predict the different failure damages and responses of laminated beams from the initial loading to the final failure. The numerical results obtained using the present element compare favorably with those given by the analytic approaches. It is observed that the numerical results are very close to the analytical results, which demonstrates the accuracy of the present element. Finally, several parameters, such as fiber orientations, stacking sequences, and boundary conditions, are considered to determine and understand their effects on the strength of these laminated beams.
Efficiency of Using Cored Graphitized Electrodes on Electric Arc Furnaces of Direct Current
Authors: Bogachenko А.G. , Mishchenko D.D. , Goncharov I.O. , Braginets V.I. , Neylo I.A. , Plevako Y.A. 
Published: March 2023

Abstract
An effective means for improvement of technical and economic indicators of EAF DC are graphitized cored electrodes, designed at the E.O. Paton Electric Welding Institute. The research works of the first stage, carried out in the industrial furnaces of the type EAF DC-12, showed that the arc of the cored electrode is always maintained in the center of the electrode, a stable electric mode of melting is provided on long arcs and low voltages of the power source. It was established that the voltage in the near cathode area, as well as the range of current and voltage pulsation of the cored electrode arc is significantly lower than in the standard (monolithic) graphitized electrode. These factors determined the saving of active energy, reduction of reactive power losses, increase in cos φ and reduction of the furnace noise level