bluuebunny/crossref_metadata_2025_split huggingface dataset:
Controlled Growth of Highly Oriented Perovskite Crystals in Polymer Solutions via Selective Solvent Vapor Diffusion
Authors: Li Yen‐Ting , Prakoso Suhendro Purbo , Hsu Li‐Che , Xu Xin‐Ni , Hung Chih‐Chien , Chen Ya‐Ling , Wu Yu‐Hao , Chen Wen‐Chang , Lin Bi‐Hsuan , Chiu Yu‐Cheng 
Published: September 2023

AbstractOrganic–inorganic hybrid perovskites have garnered significant attention in optoelectronics owing to their outstanding tunable optical characteristics. Controlled growth of perovskite nanocrystals from solutions is key for controlling the emission intensity and photoluminescence lifetime of perovskites. In particular, most studies have focused on controlling the crystallization of perovskite through chemical treatment using chelating ligands or physical treatment via antisolvent diffusion, and there exists a trade‐off between the photoluminescence intensity and lifetime of perovskites. Herein, a selective solvent vapor‐assisted crystallization with the aid of a functional polymer, which nanoscale perovskite crystals are grown andante from precursor solution, is presented for tuning the crystallization and optical properties of a common halide perovskite, methylammonium lead bromide (MAPbBr3). The proposed method here produces perovskite nanocrystals in the range of 200–300 nm. The spin‐coated thin film formed from the perovskite solution exhibits strong green photoluminescence with a long lifetime. The effects of the functional group and polymer dosage on the crystallization of MAPbBr3 are systematically investigated, and the crystallization mechanism is explained based on a modified LaMer model. This study provides an advanced solution process for precisely controlling perovskite crystallization to enhance their optical properties for next‐generation optoelectronic devices.
Loss of polarity protein Par3 in the intestinal epithelium promotes colitis‐associated colorectal cancer progression by damaging tight junction assembly
Authors: Luo Binbin , Song Linyi , Chen Limiao , Cai Yue , Zhang Mingwei , Wang Shenyi 
Published: September 2023

AbstractPartitioning defective 3 (Par3) is a polarity protein critical in establishing epithelial cell polarity and tight junctions (TJs). Impaired intestinal epithelial barrier integrity is closely associated with colitis‐associated colorectal cancer (CRC) progression. According to the GEO and TCGA database analyses, we first observed that the expression of Par3 was reduced in CRC patients. To understand how Par3 is related to CRC, we investigated the role of Par3 in the development of CRC using an in vivo genetic approach. Our results show that the intestinal epithelium‐specific PAR3 deletion mice demonstrated a more severe CRC phenotype in the context of azoxymethane/dextran sodium sulfate (AOM/DSS) treatment, with a corresponding increase in tumor number and inflammatory cytokines profile. Mechanistically, loss of Par3 disrupts the TJs of the intestinal epithelium and increases mucosal barrier permeability. The interaction of Par3 with ZO‐1 prevents intramolecular interactions within ZO‐1 protein and facilitates the binding of occludin to ZO‐1, hence preserving TJs integrity. Our results suggest that Par3 deficiency permits pathogenic bacteria and their endotoxins to penetrate the intestinal submucosa and activate TLR4/MyD88/NF‐κB signaling, promoting inflammation‐driven CRC development and that Par3 may be a novel potential molecular marker for the diagnosis of early‐stage CRC.
FOLR1‐stabilized β‐catenin promotes laryngeal carcinoma progression through EGFR/AKT/GSK‐3β pathway
Authors: Tuo Huawei , Li Xuemei , Du Haixia , Li Man , Xu Chenli , Yu Zizhong , Zhao Huzi 
Published: September 2023

AbstractFolate receptor 1 (FOLR1) is overexpressed in numerous epithelial malignancies; however, its role in laryngeal squamous cell carcinoma (LSCC) remains unclear. In the present study, we demonstrated that FOLR1 messenger RNA and protein expression levels were higher in LSCC tissues than in the adjacent normal tissues. Additionally, FOLR1 promoted the proliferation and migration of LSCC cells, whereas small interfering RNA‐mediated knockdown of β‐catenin abolished these effects. Moreover, FOLR1 stabilizes β‐catenin by inhibiting its ubiquitination and degradation. Furthermore, blocking the interaction between epidermal growth factor receptor (EGFR) and the EGFR/AKT/glycogen synthase (GSK)3β signaling axis both abolished FOLR1's effects on the expression and nuclear aggregation of β‐catenin. In summary, our work reveals a novel mode in which FOLR1 promotes the proliferation and migration of LSCC by enhancing the stability and nuclear translocation of β‐catenin through the EGFR/AKT/GSK3β axis.
Rainy season and crop calendars comparison between past (1950–2018) and future (2030–2100) in Madagascar
Authors: Randriamarolaza Luc Yannick Andréas , Aguilar Enric 
Published: September 2023

AbstractThis paper analyzes rainfall data to characterize the rainy season and define rice and maize crop calendars for current and future conditions in Madagascar. The daily rainfall data are taken from observational climate records and climate model simulations from the CMIP6 under the SSP245 and SSP585 scenarios. Rainy season characteristics are calibrated to fit rice and maize crop growth stages. The comparison between the past (1950–2018) and the future (2030–2100) highlights changes in the onset and cessation dates, which happen later and earlier, respectively. This causes the reduction of the rainy season duration, which affects the rice and maize crop calendars, especially its sowing or seeding periods. The worst (best) case is mainly observed in the southeast (southwest). On the one hand, the southwestern region may need to adapt to grow rice and maize crops with short or medium crop cycles in the future. In the Highland or Central land, the length of the sowing or seeding period increases. On the other hand, the North and East face a significant reduction in the length of the sowing or seeding period. Rice endures more than maize. Growing rice crops twice a year may not be possible in the future. But rather, we observe minor changes in the West. Our analysis suggests the imperative necessity to advise smallholder farmers to rely on short crop cycle varieties of rice and maize crops. Predominantly, the harvesting period is postponed. It is recommended to carefully consider our results for the definition of food policies.
Three‐dimensional super resolution ultrasound imaging with a multi‐frequency hemispherical phased array
Authors: Deng Lulu , Lea‐Banks Harriet , Jones Ryan M. , O'Reilly Meaghan A. , Hynynen Kullervo 
Published: September 2023

AbstractBackgroundHigh resolution imaging of the microvasculature plays an important role in both diagnostic and therapeutic applications in the brain. However, ultrasound pulse‐echo sonography imaging the brain vasculatures has been limited to narrow acoustic windows and low frequencies due to the distortion of the skull bone, which sacrifices axial resolution since it is pulse length dependent.PurposeTo overcome the detect limit, a large aperture 256‐module sparse hemispherical transmit/receive array was used to visualize the acoustic emissions of ultrasound‐vaporized lipid‐coated decafluorobutane nanodroplets flowing through tube phantoms and within rabbit cerebral vasculature in vivo via passive acoustic mapping and super resolution techniques.MethodsNanodroplets were vaporized with 55 kHz burst‐mode ultrasound (burst length = 145 μs, burst repetition frequency = 9–45 Hz, peak negative acoustic pressure = 0.10–0.22 MPa), which propagates through overlying tissues well without suffering from severe distortions. The resulting emissions were received at a higher frequency (612 or 1224 kHz subarray) to improve the resulting spatial resolution during passive beamforming. Normal resolution three‐dimensional images were formed using a delay, sum, and integrate beamforming algorithm, and super‐resolved images were extracted via Gaussian fitting of the estimated point‐spread‐function to the normal resolution data.ResultsWith super resolution techniques, the mean lateral (axial) full‐width‐at‐half‐maximum image intensity was 16 ± 3 (32 ± 6) μm, and 7 ± 1 (15 ± 2) μm corresponding to ∼1/67 of the normal resolution at 612 and 1224 kHz, respectively. The mean positional uncertainties were ∼1/350 (lateral) and ∼1/180 (axial) of the receive wavelength in water. In addition, a temporal correlation between nanodroplet vaporization and the transmit waveform shape was observed, which may provide the opportunity to enhance the signal‐to‐noise ratio in future studies.ConclusionsHere, we demonstrate the feasibility of vaporizing nanodroplets via low frequency ultrasound and simultaneously performing spatial mapping via passive beamforming at higher frequencies to improve the resulting spatial resolution of super resolution imaging techniques. This method may enable complete four‐dimensional vascular mapping in organs where a hemispherical array could be positioned to surround the target, such as the brain, breast, or testicles.
Exploiting high‐contrast Stokes preconditioners to efficiently solve incompressible fluid–structure interaction problems
Authors: Wichrowski Michał , Krzyżanowski Piotr , Heltai Luca , Stupkiewicz Stanisław 
Published: September 2023

AbstractIn this work, we develop a new algorithm to solve large‐scale incompressible time‐dependent fluid–structure interaction problems using a matrix‐free finite element method in arbitrary Lagrangian–Eulerian frame of reference. We derive a semi‐implicit time integration scheme which improves the geometry‐convective explicit scheme for problems involving the interaction between incompressible hyperelastic solids and incompressible fluids. The proposed algorithm relies on the reformulation of the time‐discrete problem as a generalized Stokes problem with strongly variable coefficients, for which optimal preconditioners have recently been developed. The resulting algorithm is scalable, optimal, and robust: we test our implementation on model problems that mimic classical Turek–Hron benchmarks in two and three dimensions, and investigate timing and scalability results.
A commentary on broader use of preoperative polysomnography in pediatric patients with obstructive sleep apnea
Authors: Garg Neha , Silber Elizabeth J. , Levi Jessica R. 
Published: September 2023

AbstractObstructive sleep apnea (OSA), characterized by repeated episodes of prolonged airway obstruction during sleep, is a common condition in pediatric patients ages 2 to 6. Polysomnography (PSG) testing can be used to assess the severity of OSA or obstructive sleep‐disordered breathing prior to adenotonsillectomy. The article “Characteristics and Frequency of Children With Severe Obstructive Sleep Apnea Undergoing Elective Polysomnography” by Bains et al. notes the variability in guidelines regarding indication for PSG amongst professional societies, making it difficult for physicians to determine which patients require PSG. The purpose of this commentary is to emphasize and elaborate on the potential benefit for preoperative PSG in all patients considering adenotonsillectomy as presented by the aforementioned article. With broader use of preoperative PSG, providers would have a more accurate assessment of OSA severity and to aid in surgical decision‐making and postoperative planning.
Synthesis of Transparent CuI Thin Films by a Facile Low‐Cost High Pressure (HP)‐PECVD Method at Room Temperature for the Application in Solar Cells
Authors: Sanyal Dipto Arindam , Mondal Liton , Hossain Jaker , Rashid M. Mamunur , Hossain M. Khalid , Roy Nepal C. , Rashid Talukder Mamunur 
Published: September 2023

AbstractCopper iodide (CuI) thin films were prepared on a glass substrate by a facile high pressure (HP)‐PECVD method at room temperature. For this, CuI powder was dissolved in CH3CN. The CuI vapor with plasma was investigated by Optical Emission Spectroscopic (OES) data for identifying the species in the plasma. The XRD study reveals the polycrystalline nature of the films. The SEM analyses indicate the homogeneity of the films. The EDS mapping confirms that the thin films mostly consisted of carbon followed by nitrogen, copper and iodine, respectively. The band gaps of CuI thin films were in the range of ~2.71–3.14 eV. The high transmittance and band gap engineering in HP‐PECVD‐synthesized CuI thin films indicates their potential use as window and hole transport layers in low cost solar cells.
Forecasts for a post‐Roe America: The effects of increased travel distance on abortions and births
Authors: Myers Caitlin 
Published: September 2023

AbstractI compile novel data measuring county‐level travel distances to abortion facilities and resident abortion rates from 2009 through 2020. Using these data, I implement a difference‐in‐difference research design measuring the effects of driving distance to the nearest abortion facility on abortions and births. The results indicate large but diminishing effects: an increase from 0 to 100 miles is estimated to reduce abortion rates by 19.4% and increase birth rates by 2.2%, while the next 100 miles reduces abortions by an additional 12.8% and increases births by an additional 1.6%. Based on this evidence, I forecast the effects of post‐Roe abortion bans on abortion rates by county, state, and region. In a scenario in which total abortion bans take effect in 24 states, about one‐quarter of residents seeking abortions are predicted to become trapped by distance and about three‐quarters of those who are trapped are predicted to give birth as a result.
The implications of principal leadership styles on teachers' organizational commitment in the Israeli Arab educational minority
Authors: Abd El Qader Yasmin , Benoliel Pascale 
Published: September 2023

AbstractThe current study's purpose is to present a picture of the extent to and frequency at which Israeli Arab principals are perceived as displaying the leadership styles of participative leadership versus directive leadership and transformation versus transactional leadership and then investigating the relationship of these leadership styles to teachers' organizational commitment (OC). Data were collected from two sources: senior management team members and teachers to avoid same source and common method bias: 426 participants overall from 71 high schools in the Israeli Arab educational system. Unianova analysis and hierarchical regression analyses were used to test the proposed relationships. The results of the overall model indicated that although principals in the Arab society in Israel are perceived mostly as directive leaders, participative leadership was positively associated with teacher OC beyond the specific influence of directive leadership. Changes in teacher perceptions, toward freedom of self‐expression and career advancement, seem to be reflected in the influence of principals' leadership styles on teachers' OC that are derived in part from cultural features of the school's environment. Implications for theory and practice are discussed.
Uncrewed aerial vehicle radiometric calibration: A comparison of autoexposure and fixed‐exposure images
Authors: Bagnall G. Cody , Thomasson John Alex , Yang Chenghai , Wang Tianyi , Han Xiongzhe , Sima Chao , Chang Anjin 
Published: September 2023

AbstractRemote sensing with uncrewed aerial vehicles (UAVs) is increasingly being used in agriculture to provide data on the physical characteristics of plants under field conditions. Data accuracy is critical for decision making with a high degree of confidence. In this work, we compared two multispectral camera calibration methods for image data collected with a UAV: (1) an autoexposure method that relies on a single calibration panel and a post hoc calibration, and (2) a fixed‐exposure system that uses three in‐field gray calibration panels using the empirical line calibration method. Both methods were compared to reflectance data from (a) four ground calibration targets measured with a spectroradiometer and (b) a single manned aircraft image calibrated with commercial calibration tarps. In a band‐by‐band comparison, the autoexposure method produced almost twice as much radiometric error on average compared with fixed exposure. Because remote sensing data are commonly converted to spectral indices, the calibration methods were also evaluated by calculating the visible atmospherically resistant index (VARI) and comparing the resulting data to the manned aircraft image. Similarly, the autoexposure method in this case produced twice the error of the fixed‐exposure method. The effect of the error was considered in a production agriculture context by simulating a remote sensing‐based prescription map for pesticide application in a cotton (Gossypium) field and calculating the number of mislabeled management zones. The simulation showed that the autoexposure method would be more costly to the farm because of its higher error, roughly $8.00/ha based on the assumptions made.
Peripheral airway dysfunction in prematurity‐associated obstructive lung disease identified by oscillometry
Authors: Cousins Michael , Hart Kylie , Radics Bence L. , Henderson A John , Hantos Zoltán , Sly Peter D. , Kotecha Sailesh 
Published: September 2023

AbstractIntroductionMechanisms underlying lung dysfunction after preterm birth are poorly understood. Studying phenotypes of prematurity‐associated lung disease may aid understanding of underlying mechanisms. Preterm‐born children with and without lung dysfunction and term controls were assessed using oscillometry before and after exercise, and after postexercise bronchodilation.MethodsPreterm‐born children, born at gestation of 34 weeks or less, were classified into those with prematurity‐associated obstructive lung disease (POLD; FEV1 < LLN, FEV1/FVC < LLN), prematurity‐associated preserved ratio of impaired spirometry (pPRISm; FEV1 < LLN, FEV1/FVC ≥ LLN) and compared to preterm (FEV1 ≥ LLN) and term controls (%predicted FEV1 > 90%). All children underwent cardiopulmonary exercise, and oscillometry assessment at baseline, postexercise, and after postexercise bronchodilator administration.ResultsFrom 241 participants aged 7–12 years, complete data were available from 179: 15 children with POLD and 11 with pPRISm were compared with 93 preterm and 60 term controls. POLD group, when compared to both control groups, had impaired impedance, greater resistance, more negative (greater magnitude) reactance at low frequencies, and also had decreased compliance. pPRISm group demonstrated impaired reactance and compliance compared to term controls. No differences were noted between the preterm and term controls. Exercise had little impact on oscillometry values, but children with POLD had greatest improvements after postexercise bronchodilator administration, with decreased resistance and decreased magnitude of reactance, particularly at low frequencies.ConclusionPreterm‐born children with obstructive airway disease had the greatest oscillometry impairments and the largest improvements after postexercise bronchodilator compared to control groups. Oscillometry can potentially be used to identify preterm‐born children with lung disease to institute treatment.
Unclassifiable interstitial lung disease and autoimmunity: Towards IPAF in children?
Authors: Aoust Laura , Berteloot Laureline , Drabent Philippe , Garcelon Nicolas , Bodemer Christine , Molina Thierry Jo , Bader‐Meunier Brigitte , Hadchouel Alice 
Published: September 2023

AbstractIntroductionInterstitial pneumonia with autoimmune features (IPAF) has been defined for adults with interstitial lung disease (ILD) and autoimmunity who do not meet the criteria for a specific connective tissue disease (CTD). We aimed to determine whether IPAF criteria could apply to children.MethodsWe retrospectively studied patients with ILD and autoimmunity followed at Necker Hospital between 2008 and 2019. Children were classified according to specific CTD and IPAF criteria. The epidemiology and course of the disease were studied according to the final diagnosis.ResultsAmong 27 patients, 6 fulfilled the criteria for IPAF and represented 4.5% of all patients with ILD during the study period. Other diagnoses included juvenile dermatomyositis (30%), overlap syndromes (19%), systemic lupus erythematosus (15%), systemic sclerosis (7%), mixed CTD (4%), and rheumatoid arthritis (4%). IPAF patients were more frequently boys versus CTD‐ILD patients (67% vs. 14%, p = .02). Two patients had severe respiratory distress that led to death for one of them. The course was favorable for the others, with a good response to steroids. The course tended to be more favorable for IPAF patients than for those with CTD‐ILD (0% lung fibrosis in the IPAF group vs. 43% in the CTD‐ILD group, p = .07).ConclusionWe confirmed the existence of IPAF in children. Its prevalence was lower than in adults but comparable to that found for other pediatric series. Boys were more highly represented than in CTD‐ILD. The course was favorable for most cases. Larger and more prospective studies are needed to confirm these results.
Screening for sleep disordered breathing among children hospitalized for asthma exacerbation
Authors: Gurbani Neepa , Schuler Christine L. , Ignatiuk Daniel , Albrecht Jennifer , Guo Yuping , Waits Amanda , Kercsmar Carolyn M. 
Published: September 2023

AbstractBackgroundSleep disordered breathing (SDB) may exacerbate asthma and is a treatable comorbidity.ObjectiveTo design and implement a screening process for SDB in patients hospitalized for asthma exacerbation using quality improvement (QI) methods. We sought to improve screening for SDB from zero to 60% from July 2019 to December 2020.Design/MethodsA multidisciplinary team used QI methods to screen for SDB using the Michigan pediatric sleep questionnaire (PSQ) in patients 2−18 years hospitalized for asthma exacerbation. Key interventions included: pairing the PSQ screen with another element of routine care (the asthma risk factor screen), educating staff and physicians, engaging respiratory therapists to complete the PSQ and document scores, and modifying the electronic medical record (asthma order set and flowsheet for PSQ score documentation). A run chart tracked progress and descriptive statistics were generated.ResultsThere were 2067 patients admitted for asthma exacerbation during this project. The PSQ was completed for 1531 patients (74%) overall. Of screened patients, 360 (24%) had a positive PSQ; the mean age was 8.6 years. Approximately 14 months after the project began, ~90% of children admitted for asthma were being screened; subsequently, >80% of patients were being screened until May 2022. Screening with the PSQ occurred approximately 90% of the time when routine asthma risk screens were completed.ConclusionA screening process for SDB was successfully implemented and appeared feasible and sustainable. The high proportion of positive screens reinforces the importance of evaluating for SDB in the high‐risk population of children requiring hospitalization for asthma exacerbation.
Synthesis and characterization of the energetic 5,7‐diamino‐2‐nitro‐1,2,4‐triazolo[1,5‐a]‐1,3,5‐triazine
Authors: Roux Maxwell A. , Zeller Matthias , Byrd Edward F. C. , Piercey Davin G. 
Published: September 2023

AbstractThe energetic compound 5,7‐diamino‐2‐nitro‐1,2,4‐triazolo[1,5‐a]‐1,3,5‐triazine (ANTT) was synthesized through the selective nitration of 2,5,7‐triamine‐1,2,4‐triazolo[1,5‐a]‐1,3,5‐triazine (TTT). This facile synthetic strategy yields a highly insensitive energetic nitrogen bicycle with potential for further functionalization. ANTT was chemically characterized by NMR, IR, and single crystal X‐Ray crystallography. Its energetic sensitivities (impact, friction) were experimentally determined, and its energetic performances were calculated for the first time.