bluuebunny/crossref_metadata_2025_split huggingface dataset:
Determinants of ticket prices in the secondary ticket market and the effects of COVID-19: empirical evidence from NBA ticket price data analytics
Authors: Hyun Moonsup , Soebbing Brian P. 
Published: July 2023

PurposeScholars note there are limited studies analyzing ticket price determinants. Using the common seat approach, the authors sought to advance this line of research by analyzing determinants of National Basketball Association (NBA) ticket prices in the secondary ticket market. The authors’ research seeks to ask two questions. The first is how ticket prices in the secondary market are associated with common determinants of consumer demand. The second question is what impact the COVID-19 pandemic has on ticket prices in the secondary market.Design/methodology/approachTicket prices of NBA regular season games in the 2021–2022 season were collected a week before the game day from Ticketmaster.com. A regression model was estimated with a group of independent variables: income, population, consumer preference, quality of viewing, quality of contest and pandemic (the number of COVID-19 cases).FindingsResults indicate income, population, consumer preferences (e.g. team quality and star players) and quality of viewing (e.g. arena age and weekend) impact prices. Further, the number of COVID-19 cases did reduce the ticket price.Originality/valueThe present study illuminates the theoretical significance of analyzing ticket prices as a proxy of demand in professional sport, while providing practical implications regarding the potential opportunity to increase revenue.
How substrate type and elevation drive woody communities and influence species ecological strategies in the Brazilian savanna at local scale
Authors: de Souza Patrícia Corrêa Guedes , da Luz Lima Mota Sílvia , Corrêa Rodrigo Studart , Pinto José Roberto Rodrigues 
Published: July 2023

AbstractEnvironmental heterogeneity can influence the formation of different vegetation types, even at small spatial scales. However, little is known about the factors that drive communities at local scales and species' mechanisms to adapt to different environments. Here, we investigated the influence of local environmental conditions and spatiality on the floristic variation of woody vegetation and ecological strategies of shrub‐tree species in the Brazilian savanna. We sampled adjacent sites in three substrate types—deep soil at high altitude (in Red Oxisol, with vegetation locally called Typical Cerrado—TCRO), deep soil, sandy and at low elevation (Typical Cerrado in Entisol Quartzipsamment—TCEQ), and shallow soil with rocky outcrops at high elevation (in Entisol Lithic, with vegetation known locally as Rupestrian Cerrado—RCEL). At each environment, we inventoried the vegetation, analyzed the physical–chemical soil properties, and recorded the elevation and geographic coordinates. For the most representative species of each site and the most common one among the environments, we evaluated the functional attributes (leaf nutrient concentration, specific leaf area, and maximum population heights). We showed that substrate type and elevation explain most of the floristic variation at the local scale and that the low nutritional demand constitutes the main strategy used by the species in RCEL, while in TCEQ and TCRO, species are more efficient in resource acquisition. Our results revealed that local ecological factors and processes drive species distribution. Therefore, variations in vegetation, even at the local scale must be considered to conserve biodiversity effectively.
Circadian regulation in aging: Implications for spaceflight and life on earth
Authors: Malhan Deeksha , Schoenrock Britt , Yalçin Müge , Blottner Dieter , Relόgio Angela 
Published: July 2023

AbstractAlterations in the circadian system are characteristic of aging on Earth. With the decline in physiological processes due to aging, several health concerns including vision loss, cardiovascular disorders, cognitive impairments, and muscle mass loss arise in elderly populations. Similar health risks are reported as “red flag” risks among astronauts during and after a long‐term Space exploration journey. However, little is known about the common molecular alterations underlying terrestrial aging and space‐related aging in astronauts, and controversial conclusions have been recently reported. In light of the regulatory role of the circadian clock in the maintenance of human health, we review here the overlapping role of the circadian clock both on aging on Earth and spaceflight with a focus on the four most affected systems: visual, cardiovascular, central nervous, and musculoskeletal systems. In this review, we briefly introduce the regulatory role of the circadian clock in specific cellular processes followed by alterations in those processes due to aging. We next summarize the known molecular alterations associated with spaceflight, highlighting involved clock‐regulated genes in space flown Drosophila, nematodes, small mammals, and astronauts. Finally, we discuss common genes that are altered in terms of their expression due to aging on Earth and spaceflight. Altogether, the data elaborated in this review strengthen our hypothesis regarding the timely need to include circadian dysregulation as an emerging hallmark of aging on Earth and beyond.
The Míkmaw Concordat: Rethinking Treaty Making between Indigenous Peoples and Settlers
Authors: LeBlanc Abbie 
Published: July 2023

AbstractIn 1610, the Míkmaq formed a treaty with French representatives of the Holy See. James (Sákéj) Youngblood Henderson argues in The Míkmaw Concordat (1997) that through this treaty the Míkmaq enfolded settlers into their existing international political order by extending to settlers their concept of sacred kinship. In the more than 25 years since the publication of The Míkmaw Concordat, it has received no attention from scholars of political science. This omission is unsurprising as political science struggles to account for Indigenous politics because of its traditional focus on the “Westphalian state.” This framework excludes many aspects of Indigenous political traditions, particularly their approaches to international politics, which are not reducible to state‐centric frameworks. The Concordat, as a treaty between two nonstate entities, is an example of Indigenous treaty making that can illuminate both the history of settler colonialism and how contemporary social movements are resisting the settler state.
Usefulness of blood flow evaluation by indocyanine green fluorescence in laparoscopic or robot‐assisted surgery for colorectal cancer with persistent descending mesocolon
Authors: Kusafuka Hiroshi , Hiraki Masayuki , Kawai Kenji , Ikeshima Ryo , Hata Taishi , Yanagisawa Kiminori , Kinoshita Mitsuru , Katsuyama Shinsuke , Shinke Go , Ohmura Yoshiaki , Sugimura Keijiro , Masuzawa Toru , Takeda Yutaka , Murata Kohei 
Published: July 2023

AbstractA persistent descending mesocolon is defined as a congenital fixation anomaly caused by the defective membrane fusion of the descending colon and the lateral abdominal wall. Anatomically, in persistent descending mesocolon, the left colonic artery is often shortened, and joins the marginal artery soon after its bifurcation from the inferior mesenteric artery, while the colonic mesentery often adheres firmly to the mesentery of the small intestine. As a result of these characteristics, anatomical knowledge of the persistent descending mesocolon and preservation of bowel blood flow are important during surgery for left‐sided colorectal cancer to avoid adverse events. Moreover, indocyanine green based blood flow assessment is useful for the detailed evaluation of bowel ischemia at the anastomotic site. Here we report the usefulness of blood flow evaluation using indocyanine green fluorescence in laparoscopic or robot‐assisted surgery for three patients with colorectal cancer and persistent descending mesocolons.
A replication and extension of bifactor modelling of perseverative thought in an at‐risk community sample: Exploring sex differences in the structure of PT
Authors: Koscinski Brandon , Accorso Catherine , Albanese Brian , Schmidt Norman B. , Allan Nicholas P. 
Published: July 2023

AbstractBackgroundPerseverative thought (PT) is a transdiagnostic construct associated with internalizing disorders. Bifactor models have shown that PT can be split into a general PT factor and lower‐order factors for specific forms of PT, such as rumination and worry. No bifactor study to date has investigated if the structure of PT differs across sexes.MethodsThe study consisted of 280 individuals recruited for a larger study targeting risk factors for suicidal ideation and behaviours. Participants completed a diagnostic interview and self‐report questionnaires.ResultsA two‐factor model of PT fit best in males, whereas a bifactor model fit best in females. In a structural equation model, worry was associated with generalized anxiety disorder diagnoses in females, but not males. Rumination was associated with depressive disorder diagnoses in females, but not males.ConclusionsThe present study contributes to a growing literature on PT; we found that dimensionality of PT varied by sex. We also found that relations between PT factors and generalized anxiety disorder differed by sex. Sex differences in the internalizing spectrum and related risk factors need to be considered when examining the structure and function of risk factors.
Accelerating Hair Rendering by Learning High‐Order Scattered Radiance
Authors: KT Aakash , Jarabo Adrian , Aliaga Carlos , Chiang Matt Jen‐Yuan , Maury Olivier , Hery Christophe , Narayanan P. J. , Nam Giljoo 
Published: July 2023

AbstractEfficiently and accurately rendering hair accounting for multiple scattering is a challenging open problem. Path tracing in hair takes long to converge while other techniques are either too approximate while still being computationally expensive or make assumptions about the scene. We present a technique to infer the higher order scattering in hair in constant time within the path tracing framework, while achieving better computational efficiency. Our method makes no assumptions about the scene and provides control over the renderer's bias & speedup. We achieve this by training a small multilayer perceptron (MLP) to learn the higher‐order radiance online, while rendering progresses. We describe how to robustly train this network and thoroughly analyze our resulting renderer's characteristics. We evaluate our method on various hairstyles and lighting conditions. We also compare our method against a recent learning based & a traditional real‐time hair rendering method and demonstrate better quantitative & qualitative results. Our method achieves a significant improvement in speed with respect to path tracing, achieving a run‐time reduction of 40%‐70% while only introducing a small amount of bias.
Hematopoiesis and immune reconstitution after CD19 directed chimeric antigen receptor T‐cells (CAR‐T): A comprehensive review on incidence, risk factors and current management
Authors: Galli Eugenio , Fresa Alberto , Bellesi Silvia , Metafuni Elisabetta , Maiolo Elena , Pansini Ilaria , Frioni Filippo , Autore Francesco , Limongiello Maria Assunta , Innocenti Idanna , Giammarco Sabrina , Chiusolo Patrizia , Zini Gina , Sorà Federica 
Published: July 2023

AbstractImpaired function of hematopoiesis after treatment with chimeric antigen T‐cells (CAR‐T) is a frequent finding and can interest a wide range of patients, regardless of age and underlying disease. Trilinear cytopenias, as well as hypogammaglobulinemia, B‐cell aplasia, and T‐cell impairment, can severely affect the infectious risk of CAR‐T recipients, as well as their quality of life. In this review, we provide an overview of defects in hematopoiesis after CAR‐T, starting with a summary of different definitions and thresholds. We then move to summarize the main pathogenetic mechanisms of cytopenias, and we offer insight into cytomorphological aspects, the role of clonal hematopoiesis, and the risk of secondary myeloid malignancies. Subsequently, we expose the major findings and reports on T‐cell and B‐cell quantitative and functional impairment after CAR‐T. Finally, we provide an overview of current recommendations and leading experiences regarding the management of cytopenias and defective B‐ and T‐cell function.
Striatal dopamine transporter uptake, parkinsonism and cognition in Alzheimer's disease
Authors: Kang Sungwoo , Jeon Seun , Lee Young‐gun , Ye Byoung Seok 
Published: July 2023

AbstractBackground and purposeThe correlates of motor parkinsonism in Alzheimer's disease (AD) remain controversial. The effects of nigrostriatal dopaminergic degeneration on parkinsonism and cognition in biomarker‐validated patients with AD were evaluated.MethodsThis study recruited 116 patients with AD who underwent dual‐phase 18F‐N‐(3‐fluoropropyl)‐2β‐carbon ethoxy‐3β‐(4‐iodophenyl) nortropane positron emission tomography, 18F‐florbetaben positron emission tomography, 3 T brain magnetic resonance imaging, and Unified Parkinson's Disease Rating Scale (UPDRS) and neuropsychological tests. The mean cortical thickness in the frontal, temporal, parietal and occipital cortices, and the dopamine transporter (DAT) uptake in the caudate, anterior/posterior putamen and substantia nigra were quantified. The relationship between DAT uptake, mean lobar cortical thickness, UPDRS motor score and cognition was investigated using general linear models (GLMs) after controlling for age, sex, education, intracranial volume, and deep and periventricular white matter hyperintensities. A path analysis was performed for the UPDRS motor score with the same covariates.ResultsPath analysis and multivariable GLMs for UPDRS motor score showed that lower caudate DAT uptake was directly associated with a higher UPDRS motor score, whereas caudate DAT uptake confounded the association between mean frontal/parietal thickness and UPDRS motor score. Multivariable GLMs for cognitive scores showed that lower caudate DAT uptake was associated with visuospatial/executive dysfunction independent of mean frontal or parietal thickness.ConclusionsNigrostriatal dopaminergic dysfunction is associated with parkinsonism and visuospatial/executive dysfunction in patients with AD.
Association between choroid plexus volume and cognition in Parkinson disease
Authors: Jeong Seong Ho , Jeong Hyun‐Jae , Sunwoo Mun Kyung , Ahn Sung Soo , Lee Seung‐Koo , Lee Phil Hyu , Kim Yun Joong , Sohn Young H. , Park Chae Jung , Chung Seok Jong 
Published: July 2023

AbstractBackground and purposeThe choroid plexus (CP) clears harmful metabolites from the central nervous system as part of the glymphatic system. We investigated the association of CP volume (CPV) with baseline and longitudinal cognitive decline in patients with Parkinson disease (PD).MethodsWe retrospectively reviewed the medical records of 240 patients with newly diagnosed PD who had undergone detailed neuropsychological tests and high‐resolution T1‐weighted structural magnetic resonance imaging during the initial assessment. The CPV of each patient was automatically segmented, and the intracranial volume ratio was used in subsequent analyses. The relationship between CPV and baseline composite scores of each cognitive domain was assessed using multivariate linear regression analyses. A Cox proportional hazards model was used to compare the risk of dementia conversion with CPV.ResultsCPV negatively correlated with composite scores of the frontal/executive function domain (β = −0.375, p = 0.002) after adjusting for age, sex, years of education, and parkinsonian symptom duration. The Cox regression model revealed that a larger CPV was associated with a higher risk of dementia conversion (hazard ratio [HR] = 1.509, p = 0.038), which was no longer significant after adjusting for the composite scores of the frontal/executive function domain. A mediation analysis demonstrated that the effect of CPV on the risk of dementia conversion was completely mediated by frontal/executive function (direct effect: HR = 1.203, p = 0.396; indirect effect: HR = 1.400, p = 0.015).ConclusionsBaseline CPV is associated with baseline frontal/executive function, which subsequently influences dementia conversion risk in patients with PD.
Sensitivity analysis of physical and mental health factors affecting Polycystic ovary syndrome in women
Authors: Guha Srirupa , Kodipalli Ashwini 
Published: July 2023

AbstractPolycystic ovary syndrome (PCOS) is a common condition affecting women worldwide. In this paper, we analyse physical and mental health factors affecting PCOS in women. We collected data in the form of questionnaires from women belonging to diverse backgrounds and performed a sensitivity analysis to find which factors are significant in determining the presence or absence of PCOS in women and further predict the severity of the symptoms. We implemented four types of methods for determining significant physical and mental health factors affecting the presence and degree of PCOS in women. Our analysis showed that menstrual period cycle length, menstrual period duration, regularity of menstrual periods, menstrual period flow, hair growth, eating pattern, and sleep pattern are the most significant physical health factors and feeling of worthlessness, depression, feeling of hopelessness, not able to be calm, sad and can't cheer up, can't sit still and restlessness are the most significant mental health factors in determining the presence or absence of PCOS in an individual, as well as the degree of PCOS. Furthermore, physical factors are more significant than mental health factors in determining PCOS presence and degree in the cohort of female individuals considered for the analysis.
Conceptualization of patient‐centered care in Latin America: A scoping review
Authors: Klimesch Anne , Martinez‐Pereira Alejandra , Topf Cheyenne , Härter Martin , Scholl Isabelle , Bravo Paulina 
Published: July 2023

AbstractIntroductionPatient‐centered care (PCC) has been declared as a desirable goal for health care in Latin American countries, but a coherent definition of what exactly PCC entails for clinical practice is missing. This article's aim was to identify how PCC is conceptualized in Latin American countries.MethodsScientific databases (MEDLINE, EMBASE, PsycINFO, CINAHL, Scielo, Scopus, Web of Science) and webpages of the ministries of health were searched, and experts were contacted for suggestions of literature. References were included if they contained one of a range of a priori defined keywords related to PCC in the title, were published between 2006 and 2021, and were carried out in or concerned Latin America. Definitions of PCC were extracted from the included articles and analyzed using deductive and inductive coding. Deductive coding was based on the integrative model of patient‐centeredness, which unites the definitions of PCC in the international literature (mainly North America and Europe) and proposes 16 dimensions describing PCC.ResultsThirty‐two articles were included in the analysis and about half of them were from Brazil. Numerous similarities were found between the integrative model of patient‐centeredness and the definitions of PCC given in the selected literature. The dimensions of the integrative model of patient‐centeredness that were least and most prominent in the literature were physical support and patient information, respectively. A differentiation between PCC and family‐centered care (FCC) was observed. Definitions of PCC and FCC as well as their cited references were diverse.ConclusionA considerable overlap between the conceptualization of PCC in Latin America and the integrative model of patient‐centeredness has been identified. However, there are substantial differences between countries in Latin America regarding the emphasis of research on PCC versus FCC and diverse conceptualizations of PCC and FCC exist.Patient ContributionThis scoping review takes the patient's perspective based on the integrative model of patient‐centeredness. Due to the study being a review, no patients, neither caregivers, nor members of the public, were involved.
Vibrio species bloodstream infections in Queensland, Australia
Authors: Davidson Natalie , Edwards Felicity , Harris Patrick N. A. , Laupland Kevin B. 
Published: July 2023

AbstractBackgroundVibrio species bloodstream infections have been associated with significant mortality and morbidity. Limited information is available regarding the epidemiology of bloodstream infections because of Vibrio species in the Australian context.AimsThe objective of this study was to define the incidence and risk factors for developing Vibrio species bloodstream infections and compare differences between different species.MethodsAll patients with Vibrio spp. isolated from positive blood cultures between 1 January 2000 and 31 December 2019 were identified by the state‐wide Pathology Queensland laboratory. Demographics, clinical foci of infections and comorbid conditions were collected in addition to antimicrobial susceptibility results.ResultsAbout 100 cases were identified between 2000 and 2019 with an incidence of 1.2 cases/1 million person‐years. Seasonal and geographical variation occurred with the highest incidence in the summer months and in the tropical north. Increasing age, male sex and multiple comorbidities were identified as risk factors. Vibrio vulnificus was isolated most frequently and associated with the most severe disease. Overall case fatality was 19%.ConclusionsThere is potential for increasing cases of Vibrio species infections globally with ageing populations and climate change. Ongoing clinical awareness is required to ensure optimal patient outcomes.
Immune‐related adverse events after immune check point inhibitors: Understanding the intersection with autoimmunity
Authors: Singh Namrata , Hocking Anne M. , Buckner Jane H. 
Published: July 2023

SummaryImmune checkpoint inhibitor therapies act through blockade of inhibitory molecules involved in the regulation of T cells, thus releasing tumor specific T cells to destroy their tumor targets. However, immune checkpoint inhibitors (ICI) can also lead to a breach in self‐tolerance resulting in immune‐related adverse events (irAEs) that include tissue‐specific autoimmunity. This review addresses the question of whether the mechanisms that drive ICI‐induced irAEs are shared or distinct with those driving spontaneous autoimmunity, focusing on ICI‐induced diabetes, ICI‐induced arthritis, and ICI‐induced thyroiditis due to the wealth of knowledge about the development of autoimmunity in type 1 diabetes, rheumatoid arthritis, and Hashimoto's thyroiditis. It reviews current knowledge about role of genetics and autoantibodies in the development of ICI‐induced irAEs and presents new studies utilizing single‐cell omics approaches to identify T‐cell signatures associated with ICI‐induced irAEs. Collectively, these studies indicate that there are similarities and differences between ICI‐induced irAEs and autoimmune disease and that studying them in parallel will provide important insight into the mechanisms critical for maintaining immune tolerance.