bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long-Term Effects of Treatment Modalities on Metabolic Health, Fertility Outcomes, and Cardiovascular Risks in Lean Women with Polycystic Ovary Syndrome (PCOS): A Systematic Review
Authors: Mendpara Vaidehi , Ganampet Narendranath Reddy , Afroze Sabah , Gnanasekaran Sulochana , Sahu Sweta , Atikah Rahmatulhusna , Rajpal Shreyaa , Raghavan Prithvi , Ajith Krithika , Parmar Mihirkumar P. , Venugopal Vishal 
Published: September 2023

Abstract
Oligomenorrhea with different degrees of follicular and adrenal hyperandrogenism are the hallmarks of the condition of polycystic ovary syndrome (PCOS). For some of the women in their reproductive years, this endocrine illness is incredibly prevalent and comprises a variety of disorders. There are a set of symptoms, such as hirsutism, acne, and insulin resistance, for identifying the characteristics of PCOS. Various treatment modalities have been opted for over the years for the treatment and management of this condition, among which metformin and flutamide are the most prevalent, along with lifestyle modifications as prevalent recommendations to patients. Weight management for obese patients is the most challenging aspect of PCOS management. Still, similar findings are found in women with lean physiology or a normal BMI, indicating that PCOS symptoms prevail and occur irrespective of the BMI, but obese or overweight women face more problems. We determined the long-term effects of treatment modalities on PCOS symptoms and their improvement. Metformin was reported to primarily increase the blood levels of glucose as well as BMI. Blood pressure was also maintained among various researchers, and DHEAS levels were also altered along with serum sex hormone-binding globulin in the plasma of patients undergoing treatments specific for PCOS patients with a normal BMI or lean PCOS. Further studies with more extensive parameters being employed need to be conducted for the determination of the exact mechanism and cause of the disease to ease the treatment process.
Robotic Hartmann’s reversal – feasibility and technical aspects
Authors: Barone Mirko , Ippoliti Massimo , Masetti Michele , Mucilli Felice 
Published: September 2023

Abstract
Hartmann’s reversal as a staged procedure after emergency surgery is a major abdominal operation with undeniable skill-demanding steps. The robotic approach and its advantages seem to be a safe and feasible technique and could overcome necessary technical compromises of laparoscopy, ensuring a significant reduction in restoration failures or conversion.
Parameter estimation for stable distributions and their mixture
Authors: Hajjaji Omar , Manou-Abi Solym , Slaoui Yousri 
Published: September 2023

Abstract
In this paper, we consider parameter estimation of univariate α-stable distributions and their mixture. We propose firstly an estimation method based on the characteristic function by the use of a Gaussian kernel estimator of the density distribution. The choice of the optimal bandwidth parameter was done using a plug-in method. We highlight another estimation procedure for the maximum likelihood framework based on the false-position algorithm to find a numerical root of the log-likelihood through the score functions. In the case of a mixture α-stable distributions, the EM algorithm and the Bayesian estimation method were modified in order to propose an efficient tool for parameter estimation. Although we have limited the mixture study to two components, the proposed methods can be generalized to several components of mixture. A simulation study is conducted to evaluate the performance of our methods which are then applied to real data. Our results seems accurately estimating mixture of α-stable distributions. The application concerned the estimation of reproduction number of the Covid-19 in Mayotte and the Enzyme dataset density distribution. We compare the proposed methods along with a detailed discussion, and we conclude with some other forthcoming works.
Mapping Respiratory Health Digital Interventions in South and Southeast Asia: Protocol for a Scoping Review
Authors: Evans Laura , Evans Jay , Fletcher Monica , Abdullah Adina , Ahmed Zakiuddin 
Published: September 2023

Background
The last 2 decades have been a time of exponential growth and maturation for digital health, while the global burden of respiratory disease continues to grow worldwide. Leveraging digital health interventions (DHIs) to manage and mitigate respiratory disease and its adverse health effects presents itself as an obvious path forward.

Objective
We aimed to understand the current digital landscape and enabling environment around respiratory health to reduce costs, avoid duplication, and understand the comprehensiveness of DHIs.

Methods
This study will follow a scoping review methodology as outlined by Arksey and O’Malley, the Joanna Briggs Institute, and the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) checklist. MEDLINE, Embase, CINAHL, PsycINFO, Cochrane Library, Web of Science, PakiMedNet, and MyMedR databases will be searched along with key websites, repositories, and gray literature databases. The terms “respiratory health,” “digital health,” “South Asia,” and “Southeast Asia,” as well as related terms will be searched. The results will be screened for duplicates and then against the inclusion and exclusion criteria. For the studies included, data will be extracted, collated, and analyzed.

Results
The scoping review was started in July 2023 and will be finalized by February 2024. Results will be presented following the World Health Organization’s classification of DHIs to categorize interventions in a standardized format and the mobile health evidence reporting and assessment checklist to report on the effectiveness of interventions. Further exposition of the evidence extracted will be presented through narrative synthesis.

Conclusions
As DHIs continue to proliferate, the need to understand the current landscape becomes more pertinent. In this scoping review, we will seek to more clearly understand what digital health tools and technologies are being used in the current landscape of digital health in South and Southeast Asia for respiratory health and to what extent they are addressing the respiratory health needs of the region. The results will inform recommendations on digital health tools for respiratory health in South and Southeast Asia will help funders and implementers of DHIs leverage existing technologies and accelerate innovations that address documented gaps in the studied countries.

International Registered Report Identifier (IRRID)
DERR1-10.2196/52517
STUDY OF DETERMINANTS OF PERSISTENT POSTPARTUM HYPERTENSION AT 6 W IN WOMEN WITH PRE-ECLAMPSIA
Authors: CHANDRA VAISHALI , AGGARWAL KIRAN , RUMMAN AASIA 
Published: September 2023

Objective: Pre-eclampsia is a pregnancy disorder with hypertension and proteinuria. Abnormal placental development and maternal/fetal genetic factors contribute to its pathogenesis. Women with pre-eclampsia are at higher risk of chronic hypertension, emphasizing the importance of postnatal monitoring and preventive measures.
Methods: The study was conducted at the Department of Obstetrics and Gynaecology, Lady Hardinge Medical College and Smt. Sucheta Kriplani Hospital, New Delhi, from November 2017 to March 2019. Ethical clearance and informed consent were obtained. A total of 150 consecutive women with pre-eclampsia were included. Detailed history, clinical examination, and investigations were conducted. Women were followed until discharge and at 6 w postpartum. Determinants of persistent postpartum hypertension were compared between two groups, and statistical analysis was performed.
Results: This study aimed to investigate the clinical and biochemical determinants of persistent postpartum hypertension at 6 w in women with pre-eclampsia. A total of 125 out of 150 eligible women with pre-eclampsia were followed up at 6 w postpartum. Socio-demographic, clinical, obstetrical, and treatment-related parameters were analyzed, and logistic regression. A p-value of <0.05 was considered significant.
Conclusion: In conclusion, parity and previous history of hypertension consistently emerge as risk factors for persistent postpartum hypertension in women with pre-eclampsia, variations in the literature call for further research to reconcile discrepancies and enhance understanding.
SCREENING OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS AMONG HEALTHCARE WORKERS AND THEIR ANTIBIOTIC SUSCEPTIBILITY PATTERN IN A TERTIARY CARE HOSPITAL
Authors: BONANGI SRIVANI VIJAYA SUBHASHINI , BADAMPUDI S. S. VIJAYA SRI 
Published: September 2023

Objective: Colonization of Staphylococcus aureus in the nasal flora has been proven to play an important role in the transmission of infections. Health care workers carrying Staphylococcus aureus in their nose or skin play an important role in cross-contamination and thus result in Methicillin-resistant Staphylococcus aureus (MRSA) related hospital-acquired or community-acquired infections. Implementation of hand hygiene methods and standard precautions are helpful in reducing transmission and controlling spread. Screening for carriage of MRSA is fundamental step in nosocomial infection control. The present study was undertaken to determine the prevalence of MRSA carriage rate and study their antibiogram.
Methods: A cross-sectional study was conducted for a period of six months and samples from 185 HCWs working in high-risk areas were processed by standard protocols. As per CLSI guidelines, MRSA detection by disc diffusion method using Cefoxitin disc (30μg) and further determined by Epsilometer test (E-test) by interpreting Minimum inhibitory concentration (MIC) values (mcg/ml).
Results: Out of 185 nasal swabs, 53 were Staphylococcus aureus isolates. MRSA colonization is seen in (8.64%) samples. Preponderance was seen in staff nurses (10.16%). Antibiogram of MRSA isolates showed sensitivity to Vancomycin and linezolid.
Conclusion: The present study was undertaken to screen nasal carriage of MRSA among healthcare workers, as they pose a potential risk factor for nosocomial transmission leading to MRSA outbreaks. The strengthening of Infection prevention and control measures institutionalization of antimicrobial stewardship programs helps in curbing the spread of MRSA.
Process Mining Applied in a Software Project Development with SCRUM and ProM
Authors: Ramos Ezequiel O. , Rossi Rogério 
Published: September 2023

The software product is high used by the society in general and its development complexity are inputs of this research that gears into the software development processes. The mapping and modelling of software processes, as well as their standardization are not trivial tasks in the industry of software. Therefore, process mining practices can be useful for discovering or validating processes. This article presents a hypothetical software development project that uses the agile SCRUM method, Jira software, Jenkins pipeline and a process mining tool called ProM. As the project team generates many records using the software development tools, these records are considered event logs and it is be used during process mining activities. ProM allows users to identify processes from the event logs and is used with the records generated by Jira and Jenkins. The visualization of a possible process derived from the use of these event logs is presented when using the ProM tool and the Flexible Heuristics Miner algorithm. In conclusion, process mining can be useful to discover or validate existing software processes during the execution of a software project, also allowing these processes to be standardized to be used in future projects.
PENGARUH BERBAGAI KONSENTRASI KUNING TELUR DALAM PENGENCER TYRODE TERHADAP MOTILITAS DAN ABNORMALITAS SPERMA PADA SEMEN CAIR DINGIN ENTOG (Cairina moschata)
Authors: Sumarni Dini 
Published: September 2023

Penelitian ini bertujuan untuk mengetahui pengaruh berbagai konsentrasi kuning telur dalam pengencer Tyrode terhadap motilitas dan abnormalitas sperma pada semen cair dingin entog. Penelitian ini dilaksanakan pada 08 Februari-19 Maret 2022 dengan objek penelitian berupa semen dari seekor entog jantan berumur 1,5 tahun. Penelitian ini menggunakan metode Rancangan Acak Lengkap (RAL) dengan 3 perlakuan yaitu penambahan konsentrasi kuning telur sebesar 5% (P1), penambahan konsentrasi kuning telur sebesar 10% (P2), dan penambahan konsentrasi kuning telur sebesar 15% (P3). Setiap perlakuan ulang sebanyak 6 kali Data hasil penelitian dianalisis menggunakan Analisis Ragam dan dilanjutkan dengan Uji Jarak Berganda Duncan. Nilai rata-rata motilitas spermatozoa tertinggi dihasilkan pada P1 (55,10 ± 2,14%) dan P2 (52,82 ± 2,19%), dibandingkan P3 (43,48 ± 1,24%). Nilai rataan pada P1 (6,00 ± 0,79%) dan P2 (6,36 ± 0,85%) juga mampu menghasilkan abnormalitas terendah, dibandingkan P3 (7,72 ± 1,29%). Berdasarkan hasil penelitian dapat disimpulkan bahwa penambahan konsentrasi kuning telur dalam pengencer Tyrode berpengaruh terhadap motilitas dan abnormalitas sperma pada semen cair dingin entog. Penambahan kuning telur sebesar 5% dan 10% menghasilkan motilitas tertinggi dan abnormalitas sperma terendah pada semen cair dingin entog.Kata kunci: kuning telur, semen entog semen cair dingin, motilitas, abnormalitas.
Analisis Pengetahuan, Pendidikan Dan Sikap Terhadap Manajemen Popok Sekali Pakai
Authors: Ernyasih Ernyasih , Pratiwi Winalda Eka , Andriyani Andriyani , Lusida Nurmalia , Mallongi Anwar 
Published: September 2023

Popok sekali pakai kini semakin banyak digunakan dan menimbulkan kesulitan besar bagi pengelolaan limbah dunia, khususnya di wilayah perkotaan. Popok sekali pakai memberikan pendekatan yang mudah dan praktis kepada orang tua dalam mengelola sampah anak mereka; namun, karena kurangnya pengetahuan tentang teknik pembuangan yang benar dan terbatasnya akses terhadap layanan pengelolaan limbah, timbullah pembuangan limbah yang berbahaya. Penelitian ini bertujuan untuk mengetahui hubungan pengetahuan, pendidikan, dan sikap ibu rumah tangga terhadap manajemen popok sekali pakai. Penelitian ini merupakan penelitian kuantitatif dengan menggunakan desain studi cross sectional dengan sampel 113 ibu rumah tangga yang mempunyai balita. Analisis data menggunakan uji univariat dan uji bivariat dengan uji chi square. Variabel yang berhubungan dengan manajemen popok sekali pakai yaitu pengetahuan (p value 0,000), Pendidikan (p value 0,001), dan sikap (p value 0,000). Kesimpulan dalam penelitian ini adalah seluruh variabel yaitu pengetahuan, pendidikan, dan sikap memiliki hubungan dengan manajemen sampah popok sekali pakai. Ibu rumah tangga dapat mengganti popok balita dengan popok yang ramah lingkungan atau bahan yang mudah didaur ulang. --- Disposable diapers are now increasingly being used and are causing major difficulties for world waste management, especially in urban areas. Disposable diapers provide parents with an easy and practical approach to managing their child's waste; however, due to a lack of knowledge of proper disposal techniques and limited access to waste management services, hazardous waste disposal occurs. This research aims to determine the relationship between knowledge, education, and attitudes of housewives towards the management of disposable diapers. This research is a quantitative study using a cross-sectional study design with a sample of 113 housewives with toddlers. Data analysis used univariate tests and bivariate tests with the chi-square test. The variables related to disposable diaper management are knowledge (p-value 0.000), education (p-value 0.001), and attitude (p-value 0.000). The conclusion of this study is that all variables, namely knowledge, education, and attitudes have a relationship with disposable diaper waste management. Housewives can replace toddler diapers with diapers that are environmentally friendly or materials that are easily recycled.
Analisis Karakteristik Kliniko-Histopatologi Pasien Kanker Ovarium di Rumah Sakit Umum Daerah Cengkareng Jakarta Barat Tahun 2016-2021
Authors: Marindawati Mieke , Ferdiana Fita , Sugiarto Sugiarto , Nadhif Ahmad 
Published: September 2023

Latar Belakang: Kanker ovarium merupakan kanker genetalia wanita yang dapat menyebabkan kematian terbanyak pada wanita. Risiko terjadinya kanker akan mengalami peningkatan secara signifikan seiring dengan bertambahnya usia dan puncaknya saat memasuki usia menopause. Tujuan: Untuk mengetahui karakteristik serta hubungan kliniko-histopatologi kanker ovarium di Rumah Sakit Umum Daerah Cengkareng Jakarta Barat tahun 2016-2021. Metode: Jenis penelitian ini merupakan deskriptif analitik dengan pendekatan retrospective cross sectional menggunakan data rekam medis. Penelitian ini menggunakan data rekam medik Rumah Sakit Umum Daerah Cengkareng periode 2016-2021. Analisis data dilakukan secara univariat dan bivariat dengan uji Chi-Square menggunakan SPSS. Hasil: Berdasarkan 43 data rekam medis, usia terbanyak adalah rentang 51-60 tahun sebanyak 14 orang (32,6%). Sedangkan pada rentang 10-20 tahun terdapat 2 orang (4,7%); usia 21-30 tahun terdapat 4 orang (9,3%); usia 31-40 tahun terdapat 6 orang (14%); usia 41-50 tahun terdapat 11 orang (25,6%); usia 61-70 terdapat 6 orang (14%). Berdasarkan keluhan dan gejala, yang mengalami nyeri perut sebanyak 3 orang, kembung 9 orang, asites 11 orang, terdapat massa kavum pelvis 5 orang, dan massa kavum abdomen 11 orang. Berdasarkan jenis histopatologi kanker ovarium, yang terbanyak adalah jenis adenokarsinoma serosum sebanyak 13 (30,2%); adenokarsinoma musinosum terdapat 10 orang (23,2%); adenokarsinoma endometrioid terdapat 7 orang (16,28%); adenokarsinoma clear cell terdapat 7 orang (16,28%); karsinoma tidak berdiferensiasi terdapat 1 orang (2,33%); Koriokarsinoma 1 orang (2,33%);tumor sel Granulosa terdapat 2 orang (4,55%); dysgerminoma terdapat 1 orang (2,33%); dan malignant germ cell terdapat 1 orang (2,33%). Variabel usia tidak berhubungan dengan jenis histopatologi kanker ovarium. Simpulan: Insiden terjadinya kanker ovarium di RSUD Cengkareng terbanyak pada rentang usia 51-60 tahun dengan usia termuda 14 tahun, tertua 66 tahun. Keluhan dan gejala yang paling sering dialami pasien adalah adanya asites dan massa di kavum abdomen. Adenokarsinoma serosum adalah jenis histopatologi terbanyak dari kanker ovarium. Tidak terdapat hubungan yang bermakna antara usia dengan jenis histopatologi kanker ovarium.
Como saber a diferença: esquizofrenia, psicose ou transtorno de humor?
Authors: Gigante Alexandre Duarte , Araujo Filho Gerardo Maria de , Rister Gilmara Peixoto 
Published: September 2023

Embora sejam doenças psiquiátricas diferentes, alguns sintomas da esquizofrenia e do transtorno bipolar, principalmente em fase eufórica, se assemelham. Tais similaridades clínicas podem levar ao diagnóstico errado e, por sua vez, a indicações de tratamento inadequadas. Por isso, saber diferenciar essas doenças é fundamental para que o paciente receba o tratamento correto. No ABP TV de hoje, vamos abordar o tema “Como saber a diferença: esquizofrenia, psicose ou transtorno de humor?”
O conhecimento de gestantes de uma Unidade Básica de Saúde no interior do Pará sobre a Depressão Pós-Parto
Authors: Lima Ana Deborah Coelho dos Santos , Abrantes Beatricia Carvalho Cunha Gomes , Almeida Giselle dos Santos , Menezes Murilo Hernesto , Garcia Caroline Lima 
Published: September 2023

Objetivo: Identificar o conhecimento de gestantes de uma Unidade Básica de Saúde (UBS) do interior do Pará sobre a depressão Pós-Parto. Métodos: Trata-se de uma pesquisa de campo de abordagem quantitativa, de caráter exploratório e descritivo, que teve como público alvo as gestantes que realizam acompanhamento pré-natal em uma UBS. A coleta de dados foi feita através de um instrumento com 23 perguntas abertas e fechadas e para a análise dos dados foi escolhido o método estatístico descritivo. Resultados: A pesquisa alcançou uma amostra de 43 gestantes, com diferentes idades gestacionais, maiores de 18 anos que aceitaram participar da presente pesquisa que foi aplicada no período entre agosto de 2022 à março de 2023. Através da pesquisa concluiu-se que de todas as 43(100%) gestantes apenas 6 (14%) receberam orientação sobre DPP no pré-natal, somente 1 (2%) sabia a diferença entre Baby Blues e DPP, e todas elas acreditam que se a mãe tiver deprimida pode afetar o bebê. Conclusão: A pesquisa concluiu que de todas as 43 gestantes, apenas 18 dessas têm conhecimento sobre as alterações emocionais que podem afetar a mulher no estado gestacional e puerperal.
越南学生汉语习得中的韵母偏误分析
Authors: Minh Khưu Chí , Thủy Cái Thi , Thi Thanh Huong Nguyen , Ngọc Huỳnh Bích 
Published: September 2023

本文对汉语和越南语韵母系统进行了较详细的描写，同时对标准越南语与越南三大方言的韵母系统进行对比，以便找出越南学生在汉语习得过程中所存在的区域性韵母偏误。通过汉越韵母系统的对比本文指出二者在构成情况、韵母数量、拼写方式、语音等方面的异同。越南学生区域性语音偏误规律的分析结果表明不同区域的越南学生有不同的韵母偏误。本文运用理论对这些偏误进行解释，从而探讨偏误的成因,以求找出克服的方案以及提出教学建议。希望本研究结果能给从事汉语语音教学的工作者提供参考，使教学工作更加有针对性，从而能够提高教学效率，同时也希望对汉语学习者有所帮助。 This article describes the vowel of Chinese and Vietnamese, and compares the vowel of standard Vietnamese and the three major Vietnamese dialects in order to find out the regional vowel errors that Vietnamese students have in the process of Chinese acquisition. Through the comparison of Chinese and Vietnamese vowel systems, the article points out similarities and differences in phonetic aspects, writing methods, number of patterns, and composition of Vietnamese and Chinese. According to the analysis results of the regional wrong phonetic rule of Vietnamese students, Vietnamese students in different regions will have different vowel errors. The article has applied theory to explain these errors, thereby finding the causes of errors, finding solutions to overcome and making recommendations on teaching. It is hoped that the results of this research can be a reference for those who do the teaching of Chinese phonetics, making the teaching on target, thereby improving the teaching efficiency, improving the teaching efficiency, and at the same time also hope it helps the learners.
مبادئ علم الطب الشرعي والسموم لرجال الأمن والقانون
Authors: M. Abdul Mabud Raja 
Published: September 2023

تناول الكتاب الطب الشرعي باعتباره علمًا من العلوم التي تختص بتوظيف الخبرة الطبية لحل المشكلات ذات الصبغة الطبية المعروضة أمام جهات التحقيق والقضاء في مجالات الطب المختلفة، ودراسة طلاب القانون وكذلك العلوم الأمنية للطب الشرعي لها أهمية كبيرة في مستقبلهم المهني؛ ذلك لأن كل واحد منهم سيحتاج في حياته اللاحقة إلى مساعدة الطب الشرعي في عمله اليومي، سواء أكان قاضيًا أم محاميًا أو نائبًا عامًّا أو محققًا أو باحثًا جنائيًّا؛ وذلك لأن الطبيب الشرعي هو الطبيب المختص الذي يُسْتَعَان بمعلوماته وخبرته الطبية لخدمة العدالة عن طريق كشف غموض الجانب الطبي من القضايا المختلفة التي تُعْرَض عليه من قِبَل القضاء، وهذا هو الدافع لوضع هذا الكتاب لرجال الأمن والقانون.
وقد قَسَّمَ الكتابُ مجالَ الطب الشرعي إلى قسمين أساسيين، ويرتبط بهذين القسمين كثير من العلوم الفنية الطبية الشرعية، مثل: الأدلة الجنائية، الكيمياء الطبية الشرعية، البصمات، الأسلحة والمتفجرات، بحوث الدم، أبحاث الخطوط اليدوية، وهذان القسمان هما:
أولاً: الطب الشرعي المَرَضِيّ، ويختص بتحديد سبب الوفاة ونوع الوفاة من حيث كونها وفاة طبيعية أو غير طبيعية من خلال فحص وتشريح الجثث في القضايا الطبية الشرعية المتعلقة بالمتوفين.
ثانيًا: الطب الشرعي السريري، ويختص هذا القسم بالمسائل الطبية ذات البعد الشرعي أو القانوني في الأشخاص الأحياء، وتشمل:
• قضايا الاعتداءات الجنسية في الإناث والذكور.
• قضايا تحديد الإصابات ونسبة العجز لدى المصاب في حالة الاعتداءات الجسدية.
• تقدير السن.
• تقدير الصلاحية العقلية للفرد.
وجاء الكتاب مشتملاً على أحد عشر فصلاً:
الفصل الأول: معاينة مسرح الحادث، الفصل الثاني: الاستعراف، الفصل الثالث: الوفاة، الفصل الرابع الجروح، الفصل الخامس الأسلحة النارية وآثارها، الفصل السادس الاختناق، الفصل السابع: الحرائق والحروق، الفصل الثامن، الجرائم الجنسية وإسقاط المرأة الحامل، الفصل التاسع: ضوابط وأخلاقيات ممارسة الطب، الفصل العاشر: تزوير الكتابة اليدوية، الفصل الحادي عشر: السموم وأهميتها من الوجهة الطبية الجنائية.