bluuebunny/crossref_metadata_2025_split huggingface dataset:
A novel approach to expedite evidence to impact in pre-eclampsia: co-developed policy labs in Zambia and Sierra Leone
Authors: Kuhrt Katy , Mabula-Bwalya Chileshe , Boulding Harriet , Beardmore-Gray Alice , Ridout Alexandra , Koroma Osman , Sam Betty , Williams Prince Tommy , Smart Francis , Meleki Isabel , Mwila Meek , Chileshe Mubanga , Mawere Racheal , Hurrell Alice , Mbiiza Christabel , Fernandez-Turienzo Cristina , Sandall Jane , Vwalika Bellington , Shennan Andrew , Bramham Kate 
Published: January 2025

AbstractPre-eclampsia is a leading cause of maternal and neonatal mortality; 30,000 pre-eclampsia-related maternal deaths occur annually, with 70% in Sub-Saharan Africa (SSA) and 16% in South Asia. We have shown that early, accurate detection of hypertension combined with planned early delivery in women with late preterm pre-eclampsia significantly reduces stillbirth and severe maternal hypertension. We describe co-development and delivery of policy labs, working with The Policy Institute (King’s College London), and local stakeholders in Sierra Leone and Zambia, to expedite integration of new knowledge into pre-eclampsia care pathways, to improve care for women and babies with the worst outcomes. Policy labs are a unique, user-centric engagement approach, bringing diverse stakeholders together in co-designing strategies for translation of evidence into policy and impact. Both labs were facilitated by local, well-respected female team members, and addressed co-developed questions: ‘How can we improve timely detection and appropriate action in women with pre-eclampsia?’ (Sierra Leone); ‘What are enablers and barriers to offering planned early delivery between 34 and 37 weeks?’(Zambia). Participants at both labs identified lack of pre-eclampsia awareness as a key barrier, and recommended local co-design of community-based strategies to increase access to timely pre-eclampsia management. We demonstrated policy labs as an effective approach in two low-and middle income settings to facilitate transfer of new knowledge into policy and action.
Measuring Stigma in Pediatric Oncology: A Cross-Sectional Analysis of Three Global Sites
Authors: Counts Lara E. , Tanner Robin S. , Chen Yichen , Devidas Meenakshi , Ferrara Gia , Chitsike Inam , Chokwenda Nester , Matsikidze Edith , Cáceres-Serrano Ana M. , Fuentes Lucia , Herrera Thelma Velasquez , Halalsheh Hadeel , Fraihat Nadine , Bhakta Nickhill , Jeha Sima , Santana Victor M. , Malone Sara M. , Graetz Dylan E. 
Published: January 2025

PURPOSE
Stigma contributes to fear and shame, resulting in delays in care-seeking behavior among individuals with cancer. As a social construct, stigma is affected by language, religion, culture, and local norms. This study explored pediatric cancer stigma at the time of diagnosis across diverse settings through the adaptation of two stigma measures.

METHODS
This study was conducted with adolescents and caregivers of children with osteosarcoma and retinoblastoma at three centers in Jordan, Guatemala, and Zimbabwe. The Stigma-related Social Problems (SSP) and the eight-item Stigma Scale for Chronic Illness (SSCI-8) measures were translated into Arabic, Spanish, and Shona and contextually adapted for use with adolescents and caregiver proxies. Adapted measures were pilot-tested and iteratively revised.

RESULTS
Extensive adaptations were made to both measures to make them relevant to the local pediatric contexts. The final measures were used in nine patients and 28 caregivers. The exploratory analysis found that domain-specific and overall scale scores for both measures indicate a higher level of stigma than those found in previous studies (SSP: patient [51.23], caregiver [40.74]; SSCI-8: patient [50.41], caregiver [49.78]). Paired, patient-caregiver proxy responses were analyzed, with disagreement between the pairs for both scales.

CONCLUSION
Adapted measures detected high levels of stigma among patients with pediatric cancer and their caregiver proxies and demonstrated a lack of concordance in the reports. This suggests the importance of studying stigma in this population and the need to ask patients about their stigma without using proxy measures. The required adaptations suggest a need for stigma measures developed specifically for pediatric cancer.
Treatment of Pleural Mesothelioma: ASCO Guideline Update
Authors: Kindler Hedy L. , Ismaila Nofisat , Bazhenova Lyudmila , Chu Quincy , Churpek Jane E. , Dagogo-Jack Ibiayi , Bryan Darren S. , Drazer Michael W. , Forde Patrick , Husain Aliya N. , Sauter Jennifer L. , Rusch Valerie , Bradbury Penelope A. , Cho B.C. John , de Perrot Marc , Ghafoor Azam , Graham David L. , Khorshid Ola , Lebensohn Alexandra , White Julie , Hassan Raffit 
Published: January 2025

ASCO Guidelines provide recommendations with comprehensive review and analyses of the relevant literature for each recommendation, following the guideline development process as outlined in the

ASCO Guidelines Methodology Manual

. ASCO Guidelines follow the

ASCO Conflict of Interest Policy for Clinical Practice Guidelines

.

Clinical Practice Guidelines and other guidance (“Guidance”) provided by ASCO is not a comprehensive or definitive guide to treatment options. It is intended for voluntary use by clinicians and should be used in conjunction with independent professional judgment. Guidance may not be applicable to all patients, interventions, diseases or stages of diseases. Guidance is based on review and analysis of relevant literature and is not intended as a statement of the standard of care. ASCO does not endorse third-party drugs, devices, services, or therapies and assumes no responsibility for any harm arising from or related to the use of this information. See complete disclaimer in
Appendix 1
and
2
(online only) for more

.

PURPOSE
To provide evidence-based recommendations to practicing physicians and others on the management of pleural mesothelioma (PM).

METHODS
ASCO convened an Expert Panel of medical oncology, thoracic surgery, radiation oncology, pathology, cancer genetics, and advocacy experts to conduct an updated literature search, which included systematic reviews, meta-analyses, randomized controlled trials, and prospective and retrospective comparative observational studies published from 2016 through 2024. Outcomes of interest included survival, disease-free or recurrence-free survival, and quality of life. Expert Panel members used available evidence and informal consensus to develop evidence-based guideline recommendations.

RESULTS
The literature search identified 110 additional relevant studies to inform the evidence base for this guideline.

RECOMMENDATIONS
Evidence-based recommendations were developed for surgical cytoreduction, immunotherapy, chemotherapy, pathology, and germline testing in patients with PM.

Additional information is available at
www.asco.org/thoracic-cancer-guidelines
.
Investor Perceptions of the Corporate Alternative Minimum Tax
Authors: Gaertner Fabio B. , Hoopes Jeffrey L. , Kelley Stacie O. , Pflitsch Max 
Published: January 2025

The Inflation Reduction Act establishes a new 15% corporate minimum tax on the adjusted financial accounting income for large U.S. corporations. Although the minimum tax is estimated to raise $222 billion over 10 years, some fear firms will manipulate their accounting earnings to reduce their tax liabilities, resulting in less revenue raised. Using an event study, we examine the extent to which investors believe this tax will reduce firm value. We examine stock market reactions around key legislative developments leading to the enactment of the book minimum tax. Our findings show targeted firms experience significantly lower stock returns than nontargeted firms during the enactment process (about 1.4%–1.8% of firm value). In aggregate, our findings are consistent with the Joint Committee on Taxation’s revenue estimates. In cross-sectional tests, we fail to find evidence that firms most likely to avoid the tax via earnings management experience more positive returns. We also fail to find less negative returns for firms most likely to pass on the tax to consumers. Overall, our results suggest investors do not expect firms to avoid this tax. Instead, they appear to expect a significant portion of the corporate minimum tax to be remitted by firms and borne by shareholders. This paper was accepted by Ranjani Krishnan, accounting. Funding: F. B. Gaertner acknowledges support from the Cynthia and Jay Ihlenfeld Professorship, M. Pflitsch acknowledges support of a postdoc fellowship of the German Academic Exchange Service (DAAD), S. O. Kelley gratefully acknowledges support from the James L. Henderson Chair, and J. L. Hoopes gratefully acknowledges support from the Harold Q. Langenderfer fellowship. Supplemental Material: The data files are available at https://doi.org/10.1287/mnsc.2024.04750 .
Would you rather treat? A rare case of Mycobacterium scrofulaceum
Authors: Sheikh Junaid Zafar , Lunjani Nonhlanhla , Gul Hira , Kila Louay , Casserly Brian 
Published: January 2025

Mycobacterium scrofulaceum is a rare cause of non-tuberculous mycobacterial infection in adults, primarily affecting the immunocompromised. Pulmonary involvement has been seen in individuals with pre-existing lung pathology. We report a case of a 63-year-old female who presented with abdominal pain, cough and sputum samples yielding M. scrofulaceum, with a normal clinical examination. Initial investigations were unremarkable, prompting abdomen and pelvis computed tomography (CT), revealing minimal pericardial and ascitic fluid. Thoracic CT exhibited calcified tree-in-bud nodules and a trivial left pleural effusion. Given subdued symptoms and limited disease, discerning colonisation versus clinically relevant infection was uncertain. Due to lack of empirical data for guidance, treatment approaches at this juncture remain unclear. The patient was monitored closely for a period of one year with a plan to treat should there be evidence of active disease.
Pus in the pericardium: a pericardial-oesophageal fistula with cardiac tamponade after ablation for atrial fibrillation
Authors: Mansoor Taha , Massoudi Nahal , Bath Anandbir , Kelly Matthew , Koshy Santhosh , Tanase Armand 
Published: January 2025

Background: Pericardial/atrial oesophageal fistula (PEF/AEF) is the most feared complication of cardiac atrial fibrillation (AF) ablation. Without urgent surgical treatment, most cases of this infrequent complication rapidly prove fatal. Case report: We present an uncommon case of a 60-year-old male who had undergone an AF ablation 2 weeks prior and presented with chest pain. Following diagnosis and treatment of ST-elevation myocardial infarction (STEMI), a small pericardial effusion was noticed on computed tomography (CT) scan. Despite an initially reassuring hospital course, rapid decompensation and expansion of his purulent pericardial effusion led to his death within 24 hours of presentation. A post-mortem review of his CT imaging revealed an inconspicuous PEF. Conclusions: It is essential to maintain a high suspicion of PEF/AEF in patients presenting after AF ablation with suggestive symptoms, such as fever, chest pain/odynophagia, and neurological deficits. CT chest is the most common diagnostic modality and surgical correction is the treatment of choice.
EDUCAÇÃO EM DIREITOS HUMANOS E A INCLUSÃO DE PESSOAS COM DEFICIÊNCIA NA EDUCAÇÃO SUPERIOR: ACESSIBILIDADE EM FOCO
Authors: Magalhães Tamara França de Almeida 
Published: January 2025

As recentes políticas públicas de educação especial na perspectiva da educação inclusiva e dos direitos humanos, têm contribuído para o crescente aumento de matrículas de estudantes com deficiência na educação superior. Este cenário tem suscitado, nas instituições de ensino superior, a necessidade de reestruturação de sua organização física e acadêmica, alicerçada em uma cultura capacitista direcionada às pessoas com deficiência. Nesta direção, compreendendo que atualmente a acessibilidade configura-se como um direito humano fundamental da pessoa com deficiência, este estudo tem como objetivo apresentar a importância do processo de consolidação da educação especial numa perspectiva inclusiva e dos direitos humanos, identificando a trajetória de atuação destas políticas na educação superior. Para isso, foi desenvolvida uma pesquisa bibliográfia dos referenciais que tratam sobre estas temáticas na educação superior, bem como dos documentos que integram o escopo das políticas desta natureza. Os dados foram analisados tendo em vista os pressupostaos da pesquisa qualitativa em diálogo com a Abordagem Histórico-Cultural do desenvolvimento humano e indicaram que as políticas de educação especial na perspectiva da educação inclusiva e dos direitos humanos na educação superior, corroboram para a compreensão da acessibilidade como um direito humano fundamental no processo de inclusão da pessoa com deficiência também nestes espaços.
SCHWARCZ, Lilia Moritz. Óculos de cor: ver e não enxergar. São Paulo: Companhia das Letrinhas, 2022. v. 1. 144 p.
Authors: Carnaval Marilya Mariany 
Published: January 2025

O livro de literatura juvenil Óculos de cor: ver e não enxergar, escrito pela historiadora e antropóloga Lilia Moritz Schwarcz e ilustrado por Suzane Lopes, foi publicado no Brasil em 2022 pela Editora Companhia das Letrinhas. O livro foi vencedor do Prêmio Jabuti em 2023 na categoria juvenil.
No prefácio do livro Óculos de Cor, a autora cita a frase “não se estuda o escravismo sem emoção e sem um sentimento de vergonha e remorso”1 e afirma que a escravidão — um sistema que criou formas de violência e crueldade desenvolvidas coletivamente por vários povos europeus — é um trauma histórico que ainda não foi elaborado o suficiente e muito menos superado no Brasil, destacando sua posição como uma pessoa/escritora branca. Ao trazer a reflexão do racismo contemporâneo em seu livro, a autora coloca que não há como não sentir vergonha e remorso, mesmo que a história do livro, criada por ela, seja de uma aventura com personagens que apontam para “janelas de esperanças” (Schwarcz, 2022, p. 9).
ChatGPT-4o can serve as the second rater for data extraction in systematic reviews
Authors: Motzfeldt Jensen Mette , Brix Danielsen Mathias , Riis Johannes , Assifuah Kristjansen Karoline , Andersen Stig , Okubo Yoshiro , Jørgensen Martin Grønbech 
Published: January 2025

Background
Systematic reviews provide clarity of a bulk of evidence and support the transfer of knowledge from clinical trials to guidelines. Yet, they are time-consuming. Artificial intelligence (AI), like ChatGPT-4o, may streamline processes of data extraction, but its efficacy requires validation.

Objective
This study aims to (1) evaluate the validity of ChatGPT-4o for data extraction compared to human reviewers, and (2) test the reproducibility of ChatGPT-4o’s data extraction.

Methods
We conducted a comparative study using papers from an ongoing systematic review on exercise to reduce fall risk. Data extracted by ChatGPT-4o were compared to a reference standard: data extracted by two independent human reviewers. The validity was assessed by categorizing the extracted data into five categories ranging from completely correct to false data. Reproducibility was evaluated by comparing data extracted in two separate sessions using different ChatGPT-4o accounts.

Results
ChatGPT-4o extracted a total of 484 data points across 11 papers. The AI’s data extraction was 92.4% accurate (95% CI: 89.5% to 94.5%) and produced false data in 5.2% of cases (95% CI: 3.4% to 7.4%). The reproducibility between the two sessions was high, with an overall agreement of 94.1%. Reproducibility decreased when information was not reported in the papers, with an agreement of 77.2%.

Conclusion
Validity and reproducibility of ChatGPT-4o was high for data extraction for systematic reviews. ChatGPT-4o was qualified as a second reviewer for systematic reviews and showed potential for future advancements when summarizing data.
The Bimanual Observation of The Hands (BOTH): Development, reliability, and validity for stroke rehabilitation
Authors: Rand Debbie , Omer Nitsan , Levkoviz Amihai , Assadi Khalil Samar 
Published: January 2025

Importance
To efficiently perform bimanual daily tasks, bimanual coordination is needed. Bimanual coordination is the interaction between an individual’s hands, which may be impaired post-stroke, however clinical and functional assessments are lacking and research is limited.

Objectives
To develop a valid and reliable observation tool to assess bimanual coordination of individuals post-stroke.

Design
A cross-sectional study.

Setting
Rehabilitation settings.

Participants
Occupational therapists (OTs) with stroke rehabilitation experience and individuals post stroke.

Outcomes and measures
The development and content validity of BOTH included a literature review, review of existing tools and followed a 10-step process. The conceptual and operational definitions of bimanual coordination were defined as well as scoring criteria. Then multiple rounds of feedback from expert OTs were performed. OTs reviewed BOTH using the ‘Template for assessing content validity through expert judgement’ questionnaire. Then, BOTH was administered to 51 participants post-stroke. Cronbach’s alpha was used to verify internal reliability of BOTH and construct validity of BOTH was assessed by correlating it to the bimanual subtests of The Purdue Pegboard Test.

Results
Expert validity was established in two-rounds with 11 OTs. Cronbach’s alpha was α = 0.923 for the asymmetrical items, 0.897 for the symmetrical items and 0.949 for all eight items. The item-total correlations of BOTH were also strong and significant. The total score of BOTH was strongly significantly correlated with The Purdue–Both hands placement (r = .787, p < .001) and Assembly (r = .730, p < .001) subtests.

Conclusions and relevance
BOTH is a new observation tool to assess bimanual coordination post-stroke. Expert validity of BOTH was established, excellent internal reliability and construct validity were demonstrated. Further research is needed, so in the future, BOTH can be used for clinical and research purposes to address bimanual coordination post-stroke.
Assessment tools for transition readiness in adolescents with inflammatory bowel disease: A scoping review
Authors: Zuo YaHui , Li Mei , Cao JinJin , Wang JiaNan , Cai WenQian , Zhang Lu , Li Meng 
Published: January 2025

Background
Assessing the level of transition readiness in adolescents with inflammatory bowel disease is crucial; however, standardized research tools are lacking. This study aimed to map transition readiness assessment tools for adolescents with inflammatory bowel disease and determine their suitability.

Methods
A literature review following the Arksey and O’Malley scoping review methodology was conducted. By using appropriate key terms, literature on transition readiness assessment tool searches were conducted in the CNKI, WanFang, SinoMed, Pubmed, Cochrane Library, Web of Science, and CINAHL databases, with a reference search. The retrieval period was from the establishment of the databases to January 2024.

Results
A total of 2561 studies were obtained through a preliminary search, and 5 references were obtained as retrospective references. Finally, 21 studies were selected for this review. In total, 20 transition readiness assessment tools were identified. Qualitative findings were grouped into five thematic areas: descriptive characteristics of reviewed articles, development procedures, design, psychometric properties, and cohort characteristics for validity testing of transition readiness assessment tools.

Conclusions
The most appropriate way to assess the transition readiness of adolescents with inflammatory bowel disease is to select an assessment tool that is most suitable for individual needs, accompanied by a comprehensive patient evaluation. Despite some flaws in the methodology, TRM is currently the most suitable assessment tool, and more population studies are needed to validate it.
Global, regional, and national survey on burden and Quality of Care Index (QCI) of orofacial clefts: Global burden of disease systematic analysis 1990–2019
Authors: Sofi-Mahmudi Ahmad , Shamsoddin Erfan , Khademioore Sahar , Khazaei Yeganeh , Vahdati Amin , Tovani-Palone Marcos Roberto 
Published: January 2025

Background
Orofacial clefts are the most common craniofacial anomalies that include a variety of conditions affecting the lips and oral cavity. They remain a significant global public health challenge. Despite this, the quality of care for orofacial clefts has not been investigated at global and country levels.

Objective
We aimed to measure the quality-of-care index (QCI) for orofacial clefts worldwide.

Methods
We used the 2019 Global Burden of Disease data to create a multifactorial index (QCI) to assess orofacial clefts globally and nationally. By utilizing data on incidence, prevalence, years of life lost, and years lived with disability, we defined four ratios to indirectly reflect the quality of healthcare. Subsequently, we conducted a principal component analysis to identify the most critical variables that could account for the observed variability. The outcome of this analysis was defined as the QCI for orofacial clefts. Following this, we tracked the QCI trends among males and females worldwide across various regions and countries, considering factors such as the socio-demographic index and World Bank classifications.

Results
Globally, the QCI for orofacial clefts exhibited a consistent upward trend from 1990 to 2019 (66.4 to 90.2) overall and for females (82.9 to 94.3) and males (72.8 to 93.6). In the year 2019, the top five countries with the highest QCI scores were as follows: Norway (QCI = 99.9), Ireland (99.4), France (99.4), Germany (99.3), the Netherlands (99.3), and Malta (99.3). Conversely, the five countries with the lowest QCI scores on a global scale in 2019 were Somalia (59.1), Niger (67.6), Burkina Faso (72.6), Ethiopia (73.0), and Mali (74.4). Gender difference showed a converging trend from 1990 to 2019 (optimal gender disparity ratio (GDR): 123 vs. 163 countries), and the GDR showed a move toward optimization (between 0.95 and 1.05) in the better and worse parts of the world.

Conclusion
Despite the positive results regarding the QCI for orofacial clefts worldwide, some countries showed a slight negative trend.
Políticas públicas de financiamento Educacional e equidade: o exercício do Programa Dinheiro Direto na Escola
Authors: Katrib Cairo Mohamad Ibrahim , Limonta Filipi Silva , Pereira Hilda Souza 
Published: January 2025

O artigo tem como proposta discutir como as políticas públicas de financiamento educacionais no Brasil, em especial o Programa Dinheiro Direto na Escola (PDDE), do Fundo Nacional de Educação (FNDE), tem exercitado a equidade em seus Programas, visando a melhoria da qualidade da Educação Escolar Quilombola. Objetivamos refletir sobre como o PDDE tem contribuído para a consolidação de uma educação mais plural e cidadã. É perceptível o esforço das políticas de financiamento educacional, em especial a do PDDE, em possibilitar a consolidação de uma gestão escolar democrática e equânime, porém, é necessário um aprimoramento da sua legislação para que atenda as especificidades das comunidades a serem atendidas pela Política. Ressalta-se que um exercício de mudança tem sido praticado, a fim de garantir a valorização dos pertencimentos e das identidades étnico e racial no contexto de uma política pública de financiamento da educação tão duradoura como é o PDDE.