bluuebunny/crossref_metadata_2025_split huggingface dataset:
Locked in: Australia’s COVID-19 Border Closures and the Right to Leave
Authors: Jefferies Regina , McAdam Jane 
Published: June 2023

Abstract
In March 2020, Australia became one of a handful of democratic states worldwide to adopt a blanket prohibition on the right of citizens to leave its territory, whether temporarily or permanently, in response to the COVID-19 pandemic. The International Health Regulations, which bind all members of the World Health Organization (‘WHO’), including Australia, provide an international legal framework to guide the public health response to the international spread of disease in a manner which respects human rights and fundamental freedoms. The right to freedom of movement in international human rights law is enshrined in the International Covenant on Civil and Political Rights (‘ICCPR’), which Australia ratified in 1990. Although states can place restrictions on freedom of movement to protect public health, they must be appropriate to achieve their protective function, the least intrusive instrument which might achieve the desired result, and proportionate to the interest to be protected. This article argues that in adopting sweeping restrictions on outbound travel, Australia re-purposed aspects of its migration control regime—ordinarily employed to externalise its international border and prevent people from entering the country—in order to prevent Australian citizens and permanent residents from leaving Australia. The outbound travel restrictions further bypassed an analysis of the intrusiveness and proportionality of the measures themselves, and shifted the burden onto individuals to request an exemption where the regulation of exit proved overly intrusive or disproportionate in their particular circumstances. In examining parliamentary transcripts, press statements by government officials, and recently revealed data regarding outbound travel exemptions, this article raises serious questions regarding the legality of the restrictions over time and their implementation in light of international law.
Role of Winter Soil Moisture in Subsequent Summer Thermal Anomalies on the Tibetan Plateau
Authors: Lin Zouxing , Zuo Zhiyan , Wang Huan , You Qinglong , Xiao Dong , Zhang Kaiwen , Qiao Liang 
Published: June 2023

Abstract
The Tibetan Plateau (TP) exerts strong powerful thermal forcing, which plays a vital role in influencing weather–climate variations in Asia and even the Northern Hemisphere. However, the causes of thermal variation over the TP have not been fully revealed. Here, the role of winter soil moisture (SM) in subsequent summer thermal anomalies on the TP was investigated through multisource datasets for the period 1979–2014. Results indicate a significant positive relationship (r = 0.52) between winter SM and subsequent summer-mean surface air temperature (SAT). Further investigations show that more (less) winter SM results in abundant (deficient) atmospheric water vapor in subsequent summer owing to its persistence. Furthermore, Earth’s surface energy budget equation confirms that strengthened (weakened) surface downward longwave radiation caused by increased (decreased) water vapor is the dominant factor leading to SAT variations, even more significant for nocturnal SAT. The winter SM–atmospheric temperature positive relationship can extend from the surface to 200 hPa over the TP. In addition, the enhanced (weakened) atmospheric latent heat release associated with increased (decreased) water vapor content may be another important factor contributing to changes in atmospheric temperatures over the TP. Therefore, our results contribute to a better understanding of the effect of land–surface processes on thermal anomalies over the TP.

Significance Statement
Understanding the causes of thermal anomalies over the Tibetan Plateau (TP) is crucial for weather and climate variations, but the role of winter soil moisture (SM) in subsequent summer thermal effects is largely unknown. This study investigated the relationship between winter SM and thermal anomalies in subsequent summers on the TP. Results show that the above (below)-normal winter SM will cause warm (cold) atmospheric temperatures in the subsequent summer. The above (below)-normal winter SM anomalies bring increased (decreased) atmospheric water vapor in summer owing to its persistence, resulting in strengthened (weakened) downward longwave radiation and atmospheric latent heat release to heat (cool) the atmosphere.
Supporting advancement of lab animal welfare and scientific integrity in developing countries: ACURET Cage Consortium (ACCON) Project
Authors: Fakoya Francis-Adelade GO 
Published: June 2023

Research involving animals remains an essential tool to increase our understanding of how human and animal bodies work; how diseases affect them and the safety assessment of chemicals, such as pesticides, for their possible effects on human health or the environment; and how diseases can be prevented or treated via developing and testing medicines and vaccines for humans or animals. To achieve high quality science based on animal manipulations and experimentations from developing countries, adequate welfare of the lab animals needs to become sine qua non for all concerned. ACURET.ORG is in the forefront of promoting humane animal care and use for scientific purposes in developing countries, with focus on Africa, seeking to aid and facilitate aspects of Institutional Lab Animal programmes in addition to its training and education programmes in the last 11 years since its inception and incorporation eight years ago. ACURET has embarked upon a project tagged ‘ACURET Cage Consortium Project’, the provision of re-usable ‘open-top’ cages for mice and rats in place of the many varied artificial housing materials being used to hold such animals in many facilities in Africa. ACURET is seeking old but functional cages and accessories, still ‘fit for purpose’; other animal husbandry and research equipment, as donations from institutions and industry for distribution to institutions in Africa who require them to improve their lab animal welfare programme. With a phased funding support from Laboratory Animal Ltd., ACURET will be responsible for the collection of donated items from locations, re-package them for sea-shipping to NIMR in Lagos, from where they will be distributed to successful applying institutional animal facilities, on a ‘first come, first served’ basis. At the heart of the ACURET Cage Consortium Project is the enablement of researchers in Africa to engage in the essence of their research when the welfare of the laboratory animals they care for and use has been affirmed. Ultimately, we anticipate that the project will support raising the bar on Africans skilled in humane animal care and use for scientific purposes in developing countries.
Anti-Xa testing for pediatric and neonatal patients on extracorporeal membrane oxygenation
Authors: Meshulami Noy , Green Robert , Kaushik Shubhi 
Published: June 2023

Introduction To determine if anti-Xa testing is associated with improved outcomes for patients <19-years-old on ECMO. Methods We evaluated the clinical benefit of anti-Xa heparin monitoring utilizing the Bleeding and Thrombosis during ECMO (BATE) database of 514 patients <19-years-old. The BATE database includes incidences of bleeding, thrombosis, and mortality. The database also describes anti-coagulation test utilization. We grouped and analyzed patients based on ECMO indication (cardiac, respiratory, or extracorporeal cardiopulmonary resuscitation [E-CPR]) and age (neonatal vs pediatric). We constructed multivariable logistic regression models to analyze the impact of anti-Xa testing on mortality, bleeding, and thrombosis in each group. Results Across the entire population, anti-Xa testing did not have a significant effect on the incidence of mortality (43% with anti-Xa testing vs 49% without), bleeding (68% vs 74%), or thrombosis (37% vs 39%). However, among cardiac indicated patients on ECMO ( n = 207), anti-Xa testing was significantly associated with reduced odds ratio (OR) of mortality (adjusted OR 0.527, p = .040) and bleeding (adjusted OR 0.369, p = .021). In addition, among neonatal patients on ECMO ( n = 264), anti-Xa testing was associated with a significant reduction in the odds ratio of bleeding (adjusted OR 0.534, p = .046). Conclusion Anti-Xa testing is associated with improved outcomes among cardiac indicated and neonatal patients on ECMO. Additional research to find the optimal heparin monitoring regimen is needed to better support these critically ill patients. In the interim, we recommend clinicians consider utilizing anti-Xa assays as part of their heparin monitoring plan for neonatal and cardiac indicated patients on ECMO.
Normal variations of the superior vena cava and azygos venous system depiction by CT scan in the adult Thai population
Authors: Chooprasert Supaporn , Nirattisaikul Sitang , Hongsakul Keerati , Choochuen Panjai , Pakdee Wisitsak 
Published: June 2023

Background Identification of normal variations to the thoracic central venous system anatomy is essential in radiological intervention and cardiothoracic surgery to prevent complications. Purpose To estimate the prevalence and pattern of normal variations of superior vena cava (SVC) and azygos venous system as well as factors associated with normal variations of SVC. Material and Methods Venous-phase chest CT of 1336 patients were retrospectively reviewed. Age, sex, and underlying disease were recorded. SVC diameter and cross-sectional area were measured to evaluate for associations with normal variations. Results The prevalence of normal anatomical variations of SVC and azygos venous system were 0.3% and 1.5%, respectively. Duplicated SVC was the most common variations. The most common variation for the azygos venous system was the connection between the hemiazygos and accessory hemiazygos veins draining into the left brachiocephalic vein (12/1336 cases, 0.9%). The median (interquartile range [IQR]) cross-sectional area compared between normal SVC (297.2 mm2) and duplicated SVC (223.5 mm2) showed a statistically significant difference ( P = 0.033). Conclusion This study determined the prevalence of rare normal variations of the azygos venous system, a connection between the hemiazygos and accessory hemiazygos veins draining into the left brachiocephalic vein. The prevalence of normal variations of the SVC and azygos venous system in the adult Thai population was similar with that of previous publications. Cross-sectional area was the only factor with a significant association with SVC variations.
Electroacupuncture improves cardiac function after myocardial infarction by regulating the mobilization and migration of endogenous stem cells
Authors: Xuan Shou-Song , Zhao Yue , Zheng Yan , Zhu Jing , Li Han , Lu Ping-Ping , Shao Shui-Jin , Guo Hai-Dong , Mou Fang-Fang 
Published: June 2023

Objective: The aim of this study was to explore the role and mechanisms of electroacupuncture (EA) in the regulation of chemokines in endogenous stem cell mobilization and myocardial regeneration after myocardial infarction (MI). Methods: An MI model was constructed in adult male Sprague-Dawley rats by ligating the left anterior descending coronary artery. After 4 weeks of treatment, echocardiography was used to detect changes in cardiac function, and Masson’s trichrome staining was used to detect collagen deposition. In addition, immunofluorescence staining was applied to examine von Willebrand factor (vWF)-positive vessels, the expression of cardiac troponin T (cTnT) and proliferation marker Ki67, and the number of c-kit-positive, C-X-C chemokine receptor type 4 (CXCR4)-positive, and Sca-1-positive endogenous stem cells in the infarcted area. In addition, the expression of stromal cell-derived factor (SDF)-1 and stem cell factor (SCF) was detected. Results: EA increased the ejection fraction after MI, reduced collagen deposition and cellular apoptosis, and increased the number of blood vessels compared with an untreated model group. EA significantly promoted cellular proliferation, except for myocardial cells, and significantly increased the number of c-kit-, CXCR4- and Sca-1-positive stem cells. Moreover, the expression of SDF-1 and SCF in myocardial tissue in the EA group was significantly higher than that in the (untreated) MI group. Conclusions: EA appears to promote angiogenesis and reduce collagen deposition, thus improving the cardiac function of rats with MI. The underlying mechanism of action may involve endogenous stem cell mobilization mediated by SDF-1/CXCR4 and SCF/c-kit.
Treatment of arteriovenous access pseudoaneurysms using ultrasound guided balloon assisted thrombin injection: Two cases and systematic review of the literature
Authors: Tsouknidas Ioannis , Giannopoulos Stefanos , Tassiopoulos Apostolos , Koullias George 
Published: June 2023

Background: Arteriovenous fistula pseudoaneurysm (AVF-PSA) is a common complication, usually caused during dialysis cannulation, which traditionally has been treated with open and less frequently endovascular techniques. Thrombin injection, although established in the treatment of arterial pseudoaneurysms, has barely been used in the treatment of AVF-PSA, due to concerns for AVF thrombosis or proximal embolization. Methods: A systematic review was performed according to the PRISMA 2020 guidelines. PubMed and Cochrane Central databases were reviewed and all clinical reports on AVF-PSA balloon assisted percutaneous thrombin injection through July 2022 were included. The electronic search yielded five case reports. Due to between-study differences and small sample size, the findings were summarized from each report, but the results were not pooled. Additionally, we present our own experience on two patients with AVF-PSA that were treated with balloon assisted percutaneous thrombin injection Results: A total of five case reports (no of patients: 7, including ours) were included for review. Most of the patients were male ( n = 6) and the mean age was 65.9 years. The average size of the PSA was 1.6 cm. In all cases a balloon was inflated to prevent thrombin and thrombotic material intrusion into the fistula lumen, prior to thrombin injection. In one patient n-butyl cyanoacrylate and Lipiodol were used, due to thrombin non availability. Recurrence was reported in only one patient, and average follow-up is 16 months. Conclusions: Thrombin injection with concomitant balloon inflation seems to be a safe and effective treatment for arteriovenous fistula pseudoaneurysms. Future studies should be aimed at evaluating the long-term outcomes of such minimally invasive techniques.
The Association of Sanitation and Hygiene Practices With Intestinal Parasitic Infections Among Under-14 Children in Rural Dire Dawa, Eastern Ethiopia: A Community Based Cross-sectional Study
Authors: Gebru Heroda , Deyissia Negussie , Medhin Girmay , Kloos Helmut 
Published: June 2023

Background: Intestinal parasitic infections (IPIs) are neglected tropical diseases. Sanitation and hygiene are vital components for achieving sustainable control of intestinal parasitic infections. Children are the most vulnerable to intestinal parasitic infections because of their immature immune systems and frequent exposure to unsanitary environments. The aim of this study was to assess the magnitude of IPIs and associated risk factors, including sanitation and hygiene practices, among under-14-year-old children in rural Dire Dawa, eastern Ethiopia. Methods: This community-based cross-sectional ’study included 778 subjects aged 1 to 14 years. Data were collected using questionnaires and stool examinations. The direct wet-mount method and formol-ether concentration techniques were performed to identify IPIs. Data Analysis: A descriptive statistic was used to show the prevalence of IPIs. Bi-variable and multivariable analysis using the logistic regression model was carried out. Results: The outputs are presented using an adjusted odds ratio (aOR) with 95% confidence intervals (CIs). The prevalence of 5 intestinal parasites was 33.7% (95% CI = 30.4%-37%). Giardia intestinalis (15.2%) and Hymenolepis nana (11.6%) had the highest prevalence. The odds of IPIs among children of illiterate mothers were 13.1 times higher when compared with children of mothers with secondary education (aOR = 13.1, P = .02), and the odds of IPIs among children from households that have unclean latrines were 1.8 times higher when compared with children from households that have clean latrines. (aOR = 1.8, P = .03). Children from households that discard solid waste in open fields had 1.7 times higher odds of having a positive result than children from households that burn their waste (aOR = 1.7, P = .03). However, children without a swimming habit (aOR = 0.4, P = .000) and asymptomatic children (aOR = 0.3, P = .000) were protective against IPIs. Conclusions: IPIs continue to be a public health problem in rural parts of Dire Dawa. The prevalence of Giardia intestinalis and H. nana could be of public health importance in this setting. Solid waste management, latrine cleanliness, mothers’ level of education, and child swimming habits in unclean accumulated water were significantly associated with IPIs. Therefore, efforts should be made to ensure intervention, considering such risks.
Characteristics of orthognathic multidisciplinary team clinics in England. Part 1: A questionnaire survey
Authors: Brannen Sasha , Rolland Sarah , Cala Anna , Vernazza Christopher R , Paul Ninu 
Published: June 2023

Background: Orthognathic clinics across England are currently run in a multidisciplinary team (MDT) format. It is, however, likely that there is a large variation in the style of these clinics and care pathways for orthognathic patients across the country. This was a cross-sectional, online questionnaire with a primary aim to obtain information on the way orthognathic care is currently delivered throughout England. The secondary objectives were to determine the compliance to the minimum dataset for record collection. The questionnaire, disseminated to orthodontic consultants, detailed 27 items split into waiting lists for new patients, mechanics of the clinic, support for patients and record collection. Results: A total of 36 participants responded (one was excluded) to give a total of 35 questionnaire responses. Descriptive statistics were used to analyse the data. Of the participants, 34% followed up their patients as per the commissioning guidelines at 1, 2 and 5 years after treatment. Of the participants, 20% said patients’ mental health would be screened before adding them to a waiting list, with 26% of participants stating screening was not undertaken for all patients. Of the participants, 11% had available access to psychological support during the MDT meeting and 20% recorded the minimum dataset at the follow-up intervals. Conclusion: There are inconsistencies in the orthognathic MDT design across England. Acceptance criteria, support services available and records collected for patients showed substantial variation, highlighting the limited guidance offered by the commissioning guidelines and the potential need to revise the minimum dataset.
Endovascular Solutions for Abdominal Aortic Aneurysms: Fenestrated, Branched and Custom-Made Devices
Authors: Cox Kofi , Yip Ho Cheung Anthony , Geragotellis Alexander , Al-Tawil Mohammed , Jubouri Matti , Williams Ian M. , Bashir Mohamad 
Published: June 2023

Background Abdominal aortic aneurysm (AAA) has a prevalence of 4.8%. AAA rupture is associated with significant mortality, thus surgical intervention is generally required once the aneurysm diameter exceeds 5.5 cm. Endovascular aneurysm repair (EVAR) is the predominant repair modality for AAA. However, in patients with complex aortic anatomy, fenestrated or branched EVAR is a superior repair option vs standard EVAR. Fenestrated and branched endoprostheses can be off-the-shelf or custom-made, which offers a more individualised approach. Aim To summarise and evaluate the clinical outcomes achieved by fenestrated EVAR (FEVAR) and branched EVAR (BEVAR), and to explore the role of custom-made endoprostheses in contemporary AAA management. Methods A literature search using Ovid Medline and Google Scholar was conducted to identify literature pertaining to the use and outcomes of fenestrated, branched, fenestrated-branched and custom-made endoprostheses for AAA repair. Results FEVAR is an effective repair modality for patients with AAA that offers similar early survival, improved early morbidity but higher rates of reintervention in comparison to open surgical repair (OSR). Compared with standard EVAR, FEVAR is associated with similar in-hospital mortality yet higher rates of morbidity, especially regarding renal outcomes. BEVAR outcomes are rarely reported exclusively in the context of AAA repair. When reported, BEVAR is an acceptable alternative to EVAR in the treatment of complex aortic aneurysms and has similar reported complication issues to FEVAR. Custom-made grafts are a good alternative treatment option for complex aneurysms where hostile aneurysm anatomy precludes the use of conventional EVAR and sufficient time is available for the manufacturing of such devices. Conclusion FEVAR offers a very effective treatment for patients with complex aortic anatomy and has been well-characterised over the past decade. RCTs and longer-term studies are desirable for unbiased comparison of non-standard EVAR modalities.
Health and Wellness Coaching and Sustained Gains: A Rapid Systematic Review
Authors: Ahmann Elizabeth , Saviet Micah , Conboy Lisa , Smith Katherine , Iachini Barbara , DeMartin Ron 
Published: June 2023

The Transtheoretical Model of Change identifies key stages in behavior change, including a maintenance stage occurring when a behavior has been upheld for at least 6 months. Health and wellness coaching has demonstrated support for health behavior change, but maintenance of gains has received little attention. Our rapid systematic literature review characterizes both the research exploring sustained gains with health and wellness coaching and what is known about sustained gains after the completion of a health and wellness coaching engagement. Guided by The Cochrane Rapid Reviews Methods Group “Interim Guidance,” we drew 231 studies from the 2018 and 2020 Sforzo et al “Compendium of the health and wellness coaching literature,” and “Addendum…” appendices. Initial screening and coding for inclusion and exclusion criteria yielded 28 studies for data extraction. We examined studies across outcome categories (physiological, behavioral, psychological, and health risk assessment) to determine whether outcome measures were: not sustained; partially sustained; fully sustained; or improved from immediate post-intervention to a later follow-up period. Twenty-five of the 28 studies reviewed demonstrated partially, or fully, sustained or improved outcomes in one or more variables studied, with sustained gains demonstrated across outcome categories, strengthening confidence in HWC as a facilitator of lasting change.