bluuebunny/crossref_metadata_2025_split huggingface dataset:
SATIRICAL POLITENESS CONSTRUCTION IN “WAR MACHINE” MOVIE
Authors: Syaifuddin S. M. 
Published: January 2023

Not many studies considered politeness in movie as politeness that was deliberately constructed by the director for a specific purpose. This research views that in part of War Machine movie scenes contained some constructions of politeness, politeness involving satire as a means of criticism, which we called Satirical Politeness. Scenes containing actions or satiric utterances, whether delivered by speakers (S) or hearer (H) in managing their faces, were the focus of this study. Qualitative analysis of movies produced as a reaction after the attacks of 19/11/01 was called 'qualitative under fire' (Denzin, 2009a). Data were analyzed using Brown & Levinson's (1987) perspectives. They were measured by looking for Weightiness. The Weightiness was determined by how strong the ranking of imposition was. The rank of imposition (Rx) was determined by the high and low of P (position) between the speech participants, and it was determined by the far and near distance (D) of the speech participants. There were many meanings behind the facework that each actor played concerning satire. The satirical politeness in the War Machine movie applied in several ways, namely; 1) satirical attitude to show disagreement, 2) jumping politeness strategy to save the face of the interlocutor, but still attacking his face in a more relaxed way, 3) anecdotal bald on record attitude used to reduce the credibility of real characters outside the movie, 4) Creating negative stigma of a real character by attaching hedge and exaggerate acts, 5) praising with insulting meanings through Bald on record and exaggerate.
GANGGUAN BERBAHASA LATAH DI DESA BUKIT HAGU KECAMATAN LHOKSUKON KABUPATEN ACEH UTARA
Authors: Istiqamah Istiqamah , Prihatin Yulianah , Saputri Nurlima 
Published: January 2023

Masalah yang dibahas dalam penelitian ini berkenaan dengan analisis gangguan berbahasa orang berperilaku latah di Desa Bukit Hagu Kecamatan Lhoksukon Kabupaten Aceh Utara. Penelitian ini bertujuan mendeskripsikan bagaimana bentuk lingual bahasa latah berdasarkan jenis latah pada masyarakat di Desa Bukit Hagu Kecamatan Lhoksukon Kabupaten Aceh Utara, dan mengindentifikasi faktor penyebab masyarakat di Desa Bukit Hagu Kabupaten Aceh Utara berperilaku latah. Penelitian ini menggunakan metode kualitatif dan jenis penelitian deskriptif. Informan yang digunakan dalam penelitian ini adalah masyarakat di Desa Bukit Hagu. Teknik pengumpulan data, dilakukan dengan wawancara, teknik simak, rekam, dan catat. Hasil penelitian menunjukkan bahwa (1) Bentuk lingual latah yang peneliti temukan adalah (a) Kodok kodok kodok pakde ; (b) awas kaki seribu dip ehh awas kaki seribu dip ; (c) hah ada pacat hah ada pacat ; (d) ehh monyet ehh monyet ; (e) ihh bibik ada ubanya ihh bibik ada ubanya ; (f) wihhh jumpa uang wihh jumpa uang ; dan (g) derrr derrr derrr. (2) Gangguan berbahasa latah yang ditemukan ermasuk jenis latah echolalia. (3) Gangguan berperilaku latah bukan hanya terjadi pada perempuan saja, tetapi juga terjadi pada laki-laki.
Inovasi Pemasaran Kain Tenun Ikat Desa Maubesi Kecamatan Insana Tengah Kabupaten Timor Tengah Utara
Authors: Bria Lambertus Nesi , Conceicao Bazelia Maria N. Da 
Published: January 2023

Kabupaten Timor Tengah Utara didiami oleh suku Atoni yang di mana memiliki beragam corak tenun ikat. Tenun ikat yang berada di Kabupaten Timor Tengah Utara saat ini mulai memudar, disebabkan oleh proses pembuatannya yang memakan waktu cukup lama. Tujuan Penelitian untuk mengetahui tentang kondisi pengrajin kain tenun dan cara memasarkan kain tenun agar dapat dijangkau oleh seluruh masyarakat di Desa Maubesi Kecamatan Insana Tengah Kabupaten Timor Tengah Utara. Data dalam penelitian ini adalah data primer dan data sekunder. Hasil penelitian ini menunjukan bahwa kain tenun ikat memiliki nilai ekonomi yang dapat mendukung kebutuhan rumah tangga dengan motif buna memiliki harga jual beli Rp. 1.000.000-6.000.000. Motif sotis kuib tenu Rp. 200.000-550.000, dan motif sotis mateta Rp. 200.000-550.000. Bahan baku pembuat kain tenun didapat dari toko, pasar, dan kios-kios terdekat. Kemudahan mendapatkan bahan baku pembuat kain tenun ikat ini menjadi salah satu keuntungan bagi produsen. Proses pembuatan kain tenun saat ini memakan waktu lebih singkat yaitu emam bulan untuk motif buna. Sedangkan untuk motif sotis kuib tenu, dan motif sotis mateta memakan waktu selama 2-4 minggu. Inovasi pemasaran yang dilakukan sehingga dapat memberikan kepuasan terhadap konsumen adalah mengunggah hasil kain tenun tersebut dengan menaruh caption “ BISA COD“. Para penjual online mengatakan COD dengan kata lain “bisa di bayar di rumah dengan mencoba terlebih dahulu jika menyukainya boleh diambil, dan jika tidak menyukainya tidak mengapa”.
Kata Kunci: Buna, Inovasi, Kuib Tenu, Mate, dan Pemasaran
Analysis of organophosphorus pesticide residues in selected vegetables purchased from Narsingdi district of Bangladesh using QuEChERS Extraction
Authors: Tasnim Nuzat , Millat Md Nasrul , Sultana Sadia , Rahman S M Mizanur , Prodhan Mohammad Dalower Hossain 
Published: January 2023

Pesticide residues in different crops, including food grains and vegetables are burning issues in Bangladesh. Therefore, the present study was conducted to analyze organophosphorus pesticide residues in three popular vegetables (cauliflower, hyacinth bean and yard long bean) collected from five local markets of Narsingdi district of Bangladesh. The collected vegetable samples were extracted and cleaned up using Quick, Easy, Cheap, Effective, Rugged and Safe (QuEChERS) extraction technique and analyzed by Gas Chromatography (GC) equipped with Flame Thermionic Detector (FTD). A total of 45 vegetable samples were analyzed. Among the 15 analyzed samples of hyacinth bean, three samples (20 % of the total samples) contained pesticide residues above the EU-MRL and the remaining samples did not contain any detectable residues of the selected organophosphorus pesticides. In case of cauliflower, out of 15 analyzed samples, two samples (13% of the total number of samples) contained pesticide residues above the EU-MRL. In case of yard long bean, of the 15 analyzed samples, four samples (27% of the total number of samples) contained pesticide residues above the EU-MRLs. This study reveals the present status of pesticide residue contamination in the selected vegetables.
Asian Australas. J. Biosci. Biotechnol. 2022, 7 (3), 114-121
Recent Medical Graduates’ Abilities in Carrying Out Consultations with Patients: Views of Interns, Medical teachers, and Medical Graduates
Authors: Murshed Hasan , KK Alam , NI Chowdhury 
Published: January 2023

This descriptive type cross sectional study was carried out to explore the views of medical teachers, medical graduates and intern doctors regarding ability of recent graduates on consultation with patients. Study period was from January 2021 to December 2021. The study was carried out in twelve government, private and army medical colleges across Bangladesh. Sample size total 636 medical teachers, medical graduates and intern doctors. Convenience sampling technique was adopted in selecting medical college and purposive sampling technique is adopted for respondent in this study. Data were collected by self administered semi structured questionnaire and data were then compiled and analyzed using SPSS version 26. Among 636 participants, majority were intern doctors (39.3%) followed by 33.8% medical graduates and teachers (26.8%). Majority of the respondents were from government medical college i.e., 51.8% followed by 30.1% from private medical college and 18.2 % from army medical college. Study revealed that all respondents (Medical teachers, medical graduates and intern doctors) agreed that for consultation with patients, recent medical graduates are more prepared in taking history and physical examination; but least prepared in breaking bad news. Majority of the all three participants’ teachers, medical graduated and intern doctors had provided a mild positive agreement about the recent medical graduates’ patient consultation skill. None of them had given strongly positive agreement about recent medical graduates’ ability on patient consultation skill. Further research needed to generalize this study finding.
Bangladesh Journal of Medical Education Vol.14(1) January 2023: 26-34
Sistem Informasi Pendaftaran Peserta Didik Baru di MTs. Sunan Ampel Dampit
Authors: Farhan  , Mudhifatul Jannah Urnika , Choirina Priska 
Published: January 2023

Pendaftaran Peserta Didik Baru (PPDB) merupakan salah satu proses di instansi pendidikan sekolah yang berfungsi untuk mempermudah proses pendaftaran peserta didik baru. PPDB di MTs. Sunan Ampel, yang merupakan salah satu instansi di bawah naungan Yayasan Pondok Pesantren Raudlatul Ulum Annawawi ini masih dilakukan secara manual. Pendaftaran di instansi yang memiliki tujuan untuk memberikan pendidikan kepada para siswa di wilayah Desa Sumber Suko, dan sekitarnya ini menggunakan Microsoft Office Excel. Proses input data secara manual memungkinkan masih banyak terjadi kesalahan data pendaftar. Selain itu juga sistem pengarsipan formulir pendaftar peserta didik baru bisa hilang. Agar sistem pendaftaran lebih baik, maka peneliti mengembangkan sistem informasi PPDB di MTs. Sunan Ampel. Pengembangan dilakukan menggunakan metode Waterfall yang dilakukan secara berurutan, dan menggunakan metode Black Box untuk pengujian. Hasil pengujian menunjukan bahwa aplikasi berjalan dengan baik, dan hasil presentase menunjukan tingkat keberhasilan 100%. Maka dari itu aplikasi yang sudah dibangun layak digunakan. Sistem informasi pendaftaran peserta didik baru ini dapat mempermudah pendaftar untuk mendapatkan formulir serta dapat mempermudah panitia dalam melakukan rekapitulasi data pendaftar.
Perancangan Sistem Presensi Siswa Dengan Fitur Realtime Notification Whatsapp Menggunakan Scrum Framework (Studi Kasus : MTs Darul Hikam Bantur)
Authors: Sirojuddin Muhammad , Tri Utomo Listanto , Prima Darajat Pangestuti 
Published: January 2023

Perancangan sistem presensi siswa dengan fitur realtime notification whatsapp merupakan inovasi dari sistem presensi yang dipergunakan di MTs Darul Hikam Bantur saat ini, MTs Darul Hikam Bantur merupakan salah satu sekolah menegah pertama yang berada di Desa Srigonco, Kecamatan Bantur, Kabupaten Malang, dimana proses presensi atau kehadiran siswanya masih dilakukan secara konvensional dengan mencatat pada buku daftar presensi. Selain itu rendahnya tingkat kedisiplinan siswa disaat jam pelajaran membuat pihak sekolah mengirimkan surat kepada orang tua siswa agar datang ke sekolah untuk memastikan informasi yang sebenarnya. Proses yang dilakukan ini cukup memakan waktu untuk memberitahukan secara realtime kepada orang tua siswa sehingga kurang efisien dan efektif penyampaian tersebut. Untuk Menindak lanjuti hal tersebut maka perlu dibuat sebuah sistem presensi yang terkomputerisasi dengan fitur realtime notification whatsapp. Penelitian ini mengunakan kerangka kerja Scrum. Tahapan dalam pengembangan sistem dimulai dari analisis, pembuatan produk backlog, sprint, demo produk serta delivery produk. Hasil penelitian menunjukkan bahwa sistem presensi siswa ini mampu menghasilkan suatu output cetak laporan presensi siswa, jurnal menggajar dan dapat mengirimkan informasi kehadiran siswa ke wali murid.
Audit Sistem Informasi Manajemen Akademik (SIMA) Menggunakan Framework COBIT 5.0 Domain Align, Plan and Organise (APO) Studi Kasus : Universitas Islam Raden Rahmat Malang
Authors: Rohmah Nur , Wahyudi Farid , Mudhifatul Jannah Urnika , Nyndia Rahmawati Zurriat 
Published: January 2023

Universitas Islam Raden Rahmat (UNIRA) Malang menggunakan Sistem Informasi Manajemen Akademik (SIMA) untuk menunjang kegiatan pengolahan akademik. SIMA ini perlu dilakukan audit untuk mengetahui tingkat kapabilitas, sehingga dapat memberikan rekomendasi untuk membantu unit Digital Center (DC) mencapai tujuan dan menghasilkan nilai melalui tata kelola dan manajemen teknologi informasi yang baik. Proses audit ini menggunakan kerangka kerja COBIT
5.0 domain APO. Responden untuk pengambilan sampel dalam audit ini berjumlah 5 orang yang bertanggungjawab mengelola SIMA. Pengukuran tingkat kapabilitas sistem menggunakan skala penilaian level kapabilitas mulai dari level 0 (incomplete process) hingga level 5 (optimizing process). Hasil perhitungan audit SIMA yaitu bahwa tingkat kapabilitas yang diperoleh berdasarkan keseluruhan rerata adalah pada tingkatan angka 3 (established process), sehingga masih perlu dilakukan evaluasi kinerja maupun operasional tata kelola dari SIMA dan subjek yang terlibat di dalamnya karena terjadi ketidakseimbangan proses TI tersebut. Level target yang ingin dicapai adalah level 4 (predictable process), sehingga perlu disusun beberapa rekomendasi untuk mengevaluasi dan meningkatkan pelayanan akademik di UNIRA Malang
Clinical and diagnostic features of course of cerebral venous thrombosis during COVID‑19 pandemic
Authors: Klocheva E. G. , Goldobin V. V. , Olimova F. Z. , Semich V. N. , Lupinogina L. A. 
Published: January 2023

Relevance. During the COVID‑19 pandemic, there has been an increase in the frequency of cerebral venous thrombosis (CVT) by 30–60 times. At the same time, the development of CVT does not depend on the severity of COVID‑19. Diagnosis of CVT during the COVID‑19 pandemic is particularly difficult, since the most common symptom of CVT, headache, can be regarded as a manifestation of COVID‑19. A wide range of clinical symptoms and low alertness of doctors leads to late diagnosis and verification of CVT.Purpose of the study. To analyze the features of clinical manifestations and neuroimaging signs of CVT against the background of COVID‑19. Patients and methods. We examined 70 young and middle-aged patients with COVID‑19 of varying severity, who underwent inpatient treatment in angio-neurological and re-profiled infectious diseases departments of North-Western State Medical University n. a. I. I. Mechnikov (Saint Petersburg, Russia) at the age of 18 to 59 years (38.5 ± 11.58), of which 49 (70 %) women and 21 (30 %) men.Results. The most common neurological symptom in patients with CVT due to COVID‑19 was diffuse headache. The severity of COVID‑19 and the degree of lung damage did not correlate with the severity of CVT. In 32 (46 %) cases, CVT was accompanied by the development of venous stroke: ischemic – in 13 (19 %) patients, hemorrhagic – in 7 (10 %), ischemic stroke with hemorrhagic impregnation – in 12 (17 %) patients. According to the localization of the thrombus, thrombosis of the left transverse sinus was most often noted – in 39 (57 %) cases.Conclusions. The leading symptom in all patients with CVT was headache, which was not relieved by taking conventional analgesics, which caused clinical alertness of doctors. Early diagnosis of CVT ensured the immediate start of anticoagulant therapy and contributed to positive dynamics in all patients in the form of regression of neurological deficit and improvement in general condition.
Nebulization of model hydrogel nanoparticles to macrophages at the air-liquid interface
Authors: Sudduth Emma R. , Kolewe Emily L. , Graf Jodi , Yu Yinkui , Somma Joaquina , Fromen Catherine A. 
Published: January 2023

Introduction: Nanoparticle evaluation within the pulmonary airspace has increasingly important implications for human health, with growing interest from drug delivery, environmental, and toxicology fields. While there have been widespread investigations of nanoparticle physiochemical properties following many routes of administration, nanoparticle behavior at the air-liquid interface (ALI) is less well-characterized.Methods: In this work, we fabricate two formulations of poly(ethylene)-glycol diacrylate (PEGDA)-based model nanoparticles to establish an in vitro workflow allowing evaluation of nanoparticle charge effects at the ALI.Results and Discussion: Both cationic and anionic PEGDA formulations were synthesized with similar hydrodynamic diameters around ∼225 nm and low polydispersity, with expected surface charges corresponding with the respective functional co-monomer. We find that both formulations are readily nebulized from an aqueous suspension in a commercial Aeroneb® Lab Nebulizer, but the aqueous delivery solution served to slightly increase the overall hydrodynamic and geometric size of the cationic particle formulation. However, nanoparticle loading at 50 μg/ml of either formulation did not influence the resultant aerosol diameter from the nebulizer. To assess aerosol delivery in vitro, we designed a 3D printed adapter capable of ensuring aerosol delivery to transwell 24-well culture plates. Nanoparticle uptake by macrophages was compared between traditional cell culture techniques and that of air-liquid interface-cultured macrophages following aerosol delivery. Cell viability was unaffected by nanoparticle delivery using either method. However, only traditional cell culture methods demonstrated significant uptake that was dependent on the nanoparticle surface charge. Concurrently, air-liquid interface culture resulted in lower metabolic activity of macrophages than those in traditional cell culture, leading to lower overall nanoparticle uptake at air-liquid interface. Overall, this work demonstrates that base-material similarities between both particle formulations provide an expected consistency in aerosol delivery regardless of the nanoparticle surface charge and provides an important workflow that enables a holistic evaluation of aerosolizable nanoparticles.
Combined microbiome and metabolome analysis of gut microbiota and metabolite interactions in chronic spontaneous urticaria
Authors: Luo Zhen , Jin Zhangsi , Tao Xiaoran , Wang Ting , Wei Panling , Zhu Caihong , Wang Zaixing 
Published: January 2023

BackgroundThe pathogenesis of chronic spontaneous urticaria (CSU) is unclear, and it turned out to be involved in biological processes, such as autoimmunity, autoallergy, inflammation, and coagulation. The gut microbiota plays an important role in immune and inflammatory diseases. However, the relationship between chronic spontaneous urticaria and the gut microbiota remains unknown.MethodsThe stool and serum samples were taken from 15 CSU patients and 15 normal controls. Changes in the composition of gut microbiota and serum metabolism in CSU patients and normal controls were analyzed by 16S ribosomal RNA (rRNA) gene sequencing and untargeted metabolomics.ResultsThe results of 16S rRNA gene sequencing showed that compared with normal controls, CSU patients had increased α-diversity of gut microbiota and significant differences in β-diversity. At the phylum level, the relative abundance of Firmicutes increased and the relative abundance of Bacteroidetes and Proteobacteria decreased in CSU patients compared with healthy controls. At the genus level, six kinds of bacteria were significantly enriched in CSU patients and five in normal controls. Metabolomic analysis revealed altered levels of metabolites such as unsaturated fatty acids and purines. Correlation analysis of gut microbiota and metabolites showed that Lachnospira was negatively correlated with arachidonic acid, and Gemmiger was also negatively correlated with (±)8-HETE.ConclusionThis study suggests that changes in gut microbiota and metabolites may play a role in immune and inflammatory pathways in the pathogenesis of CSU patients.
Clinical Features of Patients Undergoing the Head-Up Tilt Test and Its Safety and Efficacy in Diagnosing Vasovagal Syncope in 4,873 Patients
Authors: Xu Lingping , Cao Xiangqi , Wang Rui , Duan Yichao , Yang Ye , Hou Junlong , Wang Jing , Chen Bin , Xue Xianjun , Zhang Bo , Ma Hua , Sun Chaofeng , Guo Fengwei 
Published: January 2023

Background: The head-up tilt test (HUTT) is a useful diagnostic tool in patients with suspected vasovagal syncope (VVS).Objectives: We aimed to investigate the direct drug-potentiated HUTT in patients with recurrent syncope or precursor syncope and to assess the diagnostic value of the direct drug-potentiated HUTT.Methods: The medical history and direct drug-potentiated HUTT records of patients who complained of syncope or precursor syncope and who visited The Xianyang Central Hospital from January 2016 to December 2020 were retrospectively reviewed.Results: A total of 4,873 patients (age = 43.8 ± 17.6 years; male = 2,064 [42.4%]) were enrolled in our study. Overall, 2,343 (48.1%) showed positive responses as follows: 1,260 (25.9%) with the mixed type, 34 (0.7%) with the cardioinhibitory type, 580 (11.9%) with the vasodepressor type, 179 (3.7%) with postural tachycardia syndrome (POTS), and 290 (6.0%) with orthostatic hypotension (OH). The study showed that prior to syncope or near-syncope symptoms, patients first presented an increase in heart rate (HR), followed by decreases in blood pressure (BP) and HR successively. Among the patients in the syncope group, the sensitivity of the HUTT was 65.9%, which was significantly higher than a sensitivity of 44.8% for patients in the non-syncope group (P &lt; 0.01). The sensitivity of the HUTT was higher for females than males in both the syncope group (52.6% in males and 77.9% in females, P &lt; 0.01) and the non-syncope group (36.5% in males and 50.6% in females, P &lt; 0.01). Within the four age groups (&lt;20, 21–40, 41–60, and &gt;60 years old), the sensitivities were 74.7%, 67.7%, 45.6%, and 31.2%, respectively. And all gender, age and symptom (whether suffered from a syncope or not) significantly affected the positive responses of HUTT. There were two adverse events and no deaths during the HUTT in this study.Conclusion: The direct drug-potentiated HUTT is a safe and highly sensitive tool with which to diagnose VVS. Patients with precursor syncope symptoms without syncope should undergo a HUTT, especially young females presenting with weakness and sweating, which can decrease the probability of a misdiagnosis or a missed diagnosis.
Enhanced Angiogenesis by 11βHSD1 Blockage Is Insufficient to Improve Reperfusion Following Hindlimb Ischaemia
Authors: Wu Junxi , Miller Eileen , Davidson Callam , Walker Brian R. , Hadoke Patrick W. F. 
Published: January 2023

Background: Critical limb ischaemia (CLI), which is estimated to affect 2 million people in the United States, reduces quality of life, is associated with high morbidity and mortality, and has limited treatment options. Direct stimulation of angiogenesis using proangiogenic growth factors has been investigated as a therapeutic strategy to improve reperfusion in the ischaemic leg. Despite positive outcomes in animal studies, there has been little success in clinical translation. This investigation addressed the hypothesis that angiogenesis could be stimulated indirectly in the ischaemic hindlimb by blocking 11β-hydroxysteroid dehydrogenase 1 (11βHSD1)-mediated reactivation of anti-angiogenic glucocorticoids.Method and Results: Corticosterone suppressed ex vivo angiogenesis in the mouse aortic ring assay. 11βHSD1 deletion (Hsd11b1Del1/Del1) or pharmacological inhibition (with 300 nM UE2316) which block the reactivation of glucocorticoid (i.e., the conversion of 11-dehydrocorticosterone (11DHC) to bioactive corticosterone) significantly reduced 11DHC-induced suppression of angiogenesis. In a sponge implantation model, 11βHSD1 deletion, but not pharmacological inhibition, enhanced inflammation-induced angiogenesis. By contrast, in the mouse hindlimb ischaemia model, post-ischaemic reperfusion and vascular density were not affected by either deletion or pharmacological inhibition of 11βHSD1 in young or aged mice. 3D vascular imaging suggested that hind limb reperfusion in the 1st week following induction of ischaemia may be driven by the rapid expansion of collateral arteries rather than by angiogenesis.Conclusion: 11βHSD1-mediated glucocorticoid reactivation suppressed angiogenesis ex vivo and in vivo. However, regulation of angiogenesis alone was insufficient to promote reperfusion in hindlimb ischaemia. Future investigation of post-ischaemic reperfusion should include other aspects of systemic vascular remodeling including arteriogenesis and collateral formation.