bluuebunny/crossref_metadata_2025_split huggingface dataset:
Presidential Address: BERA. Who are we? How did we get here? Where are we going?
Authors: Baumfield Vivienne 
Published: March 2023

AbstractAs we approach the fiftieth anniversary of the founding of the British Educational Research Association (BERA), Vivienne Baumfield's inaugural presidential address reflects on who we are, how we got here and where we are going. On one level the answer to these questions is straightforward. BERA is a learned society established in 1974 to support educational research by building capacity, advancing quality and promoting engagement with a strategic plan identifying priority activities over the next 5 years. So far, so good, but does this tell us what we need to know? Delivered at the BERA Conference 2022, the address explores through these questions some implications of belonging to BERA as a ‘learned society’ in the twenty‐first century.
Overview of the advances in plant microbial fuel cell technology for sustainable energy recovery from rhizodeposition
Authors: Bhattacharya Riya , Parthasarthy Vijay , Bose Debajyoti , Gulia Khushabu , Srivastava Siddhant , Roshan Kadirvel Ramesh , Shankar Ramakrishnan 
Published: March 2023

AbstractIn plant microbial fuel cells (p‐MFCs) electrochemically active microbes present around the plant root convert rhizodeposits or the organic matter into electrons, protons, and CO2. This work covers the increasing trend in research with p‐MFCs with their mechanism of operation. Different plant species and their selection criteria are also covered. Furthermore, the long‐term evaluation of such systems with its cost effectiveness and commercial and environmental perspectives are also presented. A critical aspect for bioelectricity production is the photosynthetic pathway of the plant. Additionally, the microbial communities and reactor configurations employed across different capacities are also reviewed. The challenges with bioelectricity production and the opportunity for developing p‐MFCs in conjunction with traditional MFCs are also covered. These electrogenic reactor systems harness bioelectricity without harvesting the plant and has the capacity to utilize this energy for remote power applications.
A Synthesis Review of Vitamins Involved in the Fight against Covid‐19
Authors: Mciteka Lulama P. 
Published: March 2023

AbstractAlthough literature studies on earlier viruses such as the Severe Acute Respiratory Syndrome (SARS), the Middle East Respiratory Syndrome (MERS), and other similar viruses, in terms of treatment of coronavirus suggested the repurposing of some antiviral drugs, some Covid‐19 specific treatments, general forms of treatments, the use of convalescent plasma, as well as nutritional interventions in the form of vitamins, it is imperative to interrogate the nutritional status, age, and comorbidities of each infected patient before receiving any form of treatment. In the absence of any conclusive treatment so far, the study encourages the use of all likely interventions that could help arrest the spread of the disease. In addition, the current study has a particular interest in the syntheses and applications of vitamins and their derivatives which have been touted to play a significant role in the fight against Covid‐19, namely, vitamins A–E. It must, however, be mentioned that literature is not comprehensive.
Co‐infection of dengue, scrub typhus, and typhoid during dengue outbreak in Nepal, 2022: A case report
Authors: Bhattarai Bibek Raj , Bhujel Rajshree , Pokhrel Sushant , Mishra Abhishek , Priyadarshinee Anamika 
Published: March 2023

AbstractIn midst of the recent dengue outbreak in Nepal, in 2022, the risk of co‐infection increases and may lead to fatal outcomes if the diagnosis of multiple infections is delayed. Thus, all available diagnostic approaches must be taken to decrease the burden of illness and lessen mortality.
Eyelid myokymia caused by a trigeminal schwannoma as determined by the trigeminal‐evoked blink reflex
Authors: Ito Eiji , Sugita Ryotaro , Saito Ryuta 
Published: March 2023

AbstractA 57‐year‐old man had trigeminal schwannoma in Meckel's cave with eyelid myokymia only. The evaluation of the trigeminal‐evoked blink reflex was useful for confirming eyelid myokymia and contributed to surgical decision‐making. In patients with persistent eyelid myokymia, neurophysiological and imaging evaluations may be useful for determining the underlying pathophysiology.
Acquired hemophilia A in a patient with adult‐onset Still's disease: Successful treatment with steroids
Authors: Chebbi Donia , Marzouk Sameh , Krichen Imen , El Ahmer Ikram , Snoussi Mouna , Dammak Chifa , Frikha Faten , Salah Raida Ben , Kallel Choumous , Bahloul Zouhir 
Published: March 2023

AbstractAcquired hemophilia A (AHA) is a potentially life‐threatening hemorrhagic disorder with many etiologies. We report the first case in the literature describing the association of AHA with adult‐onset Still's disease (AOSD).
Biogas‐Assisted Growth of Chlorella vulgaris in an Open Raceway Pond: Proof of Concept and Economic Assessment
Authors: Parashar Anand , Shah Narendra , Rane Milind , Shastri Yogendra 
Published: March 2023

AbstractMicroalgae are a promising source of renewable fuels and value‐added chemicals but are hampered by the high cost of cultivation. Sparging CO2 in water bodies can increase the yield and reduce the cost. This work studies the feasibility of synergistically integrating a biogas digester with a microalgae cultivation system. Raw biogas is sparged through the microalgal culture to increase the microalgae yield while also purifying biogas for further use. At laboratory scale, Chlorella vulgaris was cultivated in a 1‐L batch, and biogas was sparged for 3 h per day. For a demonstration‐scale 4000‐L raceway pond, a special contacting device was used to supply biogas to the microalgal culture. On the laboratory scale, C. vulgaris concentration increased by 30 % when sparged with biogas. Moreover, the protein and lipid contents were higher than in an air‐sparged control batch. The cultivation cost of microalgae decreased by 20 %.
Nitrogen‐Doped Electrocatalysts, and Photocatalyst in Water Splitting: Effects, and Doping Protocols
Authors: Keshipour Sajjad , Eyvari‐Ashnak Faezeh 
Published: March 2023

AbstractWater splitting has been widely studied since the reaction affords hydrogen as an energetic pollutant‐free fuel from the most abundant molecule. Electrolysis, and photolysis of water are reliable pathways for hydrogen generation in green conditions, in which a catalyst is in charge of the transformation, and manipulation of its structure predominantly impresses the reaction rate. In this review, we concentrated on the impacts of nitrogen doping on the catalyst activity in electrocatalytic and photocatalytic water splitting. Increasing conductivity, formation of new edges for evolution reaction, elevating surface area by prohibition from the aggregation of the support, enhancing transition metal deposition into the support, reducing activation energy of proton evolution, shrinking bandgap of photocatalysts, increasing light harvesting, and retarding charges recombination are the most significant results of the nitrogen doping on the catalysts. Moreover, the syntheses procedures were summarized herein to provide a comprehensive view for the nitrogen doping process.
Development of the Safe and Broad‐Spectrum Aldehyde and Ketoamide Mpro inhibitors Derived from the Constrained α, γ‐AA Peptide Scaffold
Authors: Wang Lei , Ma Chunlong , Sacco Michael Dominic , Xue Songyi , Mahmoud Mentalla , Calcul Laurent , Chen Yu , Wang Jun , Cai Jianfeng 
Published: March 2023

AbstractSARS‐CoV‐2 is still wreaking havoc all over the world with surging morbidity and high mortality. The main protease (Mpro) is essential in the replication of SARS‐CoV‐2, enabling itself an active target for antiviral development. Herein, we reported the design and synthesis of a new class of peptidomimetics‐constrained α, γ‐AA peptides, based on which a series of aldehyde and ketoamide inhibitors of the Mpro of SARS‐CoV‐2 were prepared. The lead compounds showed excellent inhibitory activity in the FRET‐based Mpro enzymatic assay not only for the Mpro of SARS‐CoV‐2 but also for SARS‐CoV and MERS‐CoV, along with HCoVs like HCoV‐OC43, HCoV‐229E, HCoV‐NL63 and HKU1. The X‐ray crystallographic results demonstrated that our compounds form a covalent bond with the catalytic Cys145. They also demonstrated effective antiviral activity against live SARS‐CoV‐2. Overall, the results suggest that α, γ‐AA peptide could be a promising molecular scaffold in designing novel Mpro inhibitors of SARS‐CoV‐2 and other coronaviruses.
Tuning Directed Photooxidation‐Induced Conversion of Pyrrole‐Based Styryl Coumarin Dual‐Color Photoconverters
Authors: Saladin Lazare , Dal Pra Ophélie , Klymchenko Andrey S. , Didier Pascal , Collot Mayeul 
Published: March 2023

AbstractInvited for the cover of this issue is the group of Mayeul Collot at the University of Strasbourg (CNRS). The image depicts the effect of simple chemical tuning on coumarin dyes to tune and improve the DPIC photoconversion mechanism. Read the full text of the article at 10.1002/chem.202203933.
Ernährungsrevolution 2.0
Authors: Weingarten Melanie , Graichen Ralph , Nagler Peter 
Published: March 2023

ZusammenfassungBevölkerung und Bedarf an Nahrungsmitteln wachsen rasant. Einhergehend steigt der Wohlstand der Menschen – vor allem in Asien. Innovation und Technologie haben dies möglich gemacht. Unser Planet erinnert uns allerdings auch immer häufiger daran, dass Einklang von Mensch und Natur essenziell für das Fortbestehen sind, und es Grenzen des Wachstums gibt. Beteiligte aus Politik, Wissenschaft, Industrie und weiteren Bereichen setzen diese Erkenntnis um und erarbeiten Lösungen für eine nachhaltige Zukunft. Die Menschheit ist und bleibt dabei dem Fleisch als traditioneller wertvoller Nahrungsquelle verbunden. Hinzu treten jedoch schmackhafte und nahrhafte Alternative Proteine und Produkte. Jede fünfte Portion Protein kann bis 2035 alternativ sein (aktuell ist es jede 50., Abbildung 8). Es gibt sehr viel Potential, wenn wir uns auf unsere Großeltern besinnen, die im Grunde ihres Herzens Flexitarier waren: „unter der Woche vegetarisch, sonntags ein Stück Braten – vielleicht die beste Lösung?“
Rate of COVID‐19 vaccination among patients with cancer who tested positive for severe acute respiratory syndrome‐coronavirus 2: Analysis of the American Society of Clinical Oncology Registry
Authors: Kurbegov Dax , Bruinooge Suanna S. , Lei Xiudong Jennifer , Kirkwood M. Kelsey , Dickson Natalie , Hattiangadi Trupti , Mileham Kathryn F. , Patrick Alicia , Williams Jen Hanley , Kaltenbaugh Melinda , Gralow Julie R. , Garrett‐Mayer Elizabeth 
Published: March 2023

AbstractBackgroundThe availability of safe and effective COVID‐19 vaccines has enabled protections against serious COVID‐19 outcomes, which are particularly important for patients with cancer. The American Society of Clinical Oncology Registry enabled the study of COVID‐19 vaccine uptake in patients with cancer who were positive for severe acute respiratory syndrome‐coronavirus 2.MethodsMedical oncology practices entered data on patients who were in cancer treatment. The cohort included patients who had severe acute respiratory syndrome‐coronavirus 2 infection in 2020 and had visits and vaccine data after December 31, 2020. The primary end point was the time to first vaccination from January 1, 2021. Cumulative incidence estimates and Cox regression with death as a competing risk were used to describe the time to vaccine uptake and factors associated with vaccine receipt.ResultsThe cohort included 1155 patients from 56 practices. Among 690 patients who received the first vaccine dose, 92% received the second dose. The median time to vaccine was 99 days. After adjustment, older patients were associated with a higher likelihood of vaccination compared with patients younger than 50 years in January through March 2021, and age exhibited a linear effect, with older patients showing higher rates of vaccination. Metastatic solid tumors (hazard ratio [HR], 0.85; 95% confidence interval [CI], 0.73–0.98) or non–B‐cell hematologic malignancies (HR, 0.71; 95% CI, 0.54–0.93) compared with nonmetastatic solid tumors, and any comorbidity (HR, 0.83; 95% CI, 0.73–0.95) compared with no comorbidity, were associated with lower vaccination rates. Area‐level social determinants of health (lower education attainment and higher unemployment rates) were associated with lower vaccination rates.ConclusionsPatient age, cancer type, comorbidity, area‐level education attainment, and unemployment rates were associated with differential vaccine uptake rates. These findings should inform strategies to communicate about vaccine safety and efficacy to patients with cancer.
Synthesis of Hydrogen‐Bonded Open‐[60]Fullerenol Dimers
Authors: Hashikawa Yoshifumi , Sadai Shumpei , Murata Yasujiro 
Published: March 2023

AbstractTwo open‐[60]fullerenols were synthesized through a selective bond cleavage by reactions with N‐oxide or singlet oxygen. Both open‐[60]fullerenols having a bis(hemiketal) moiety were aggregated via intra‐ and intermolecular hydrogen‐bondings to show a dimeric configuration in a face‐to‐face fashion where the hydroxy groups adopt a rhomboidal or chair‐like arrangement as confirmed by X‐ray diffraction analysis. The dimerization constant of one of the two open‐[60]fullerenols was measured to be 22.2±4.7 M−1 (300 K, CDCl3) which is twice as large as that of a previously‐reported open‐[60]fullerenol bearing three hydroxy groups. According to theoretical calculations, an averaged interaction energy was estimated to be ca. −1.95 kcal/mol per an H‐bonding. By a loss of a water molecule from the bis(hemiketal) moiety, these open‐[60]fullerenols are transformed into tetracarbonyl derivatives with a 16‐membered‐ring orifice. Despite being the same ring‐atom count, a larger tilt angle of one of the carbonyl groups reduces the effective orifice size as suggested by theoretical calculations.
Chromosome Analysis and Sorting Using Conventional Flow Cytometers
Authors: Ng Bee Ling 
Published: March 2023

AbstractThe fluorescent dyes Hoechst (HO) and Chromomycin A3 (CA3) are commonly used for bivariate flow karyotyping to distinguish individual chromosomes from one another based on differences in base composition and DNA content. However, analysis of chromosomes using this fluorescent dye combination requires a flow cytometer equipped with lasers of specific wavelengths and higher power than is typical of conventional flow cytometers. This unit presents a chromosome staining technique with a dye combination of DAPI and propidium iodide (PI). Chromosomes stained using this dye combination can be analyzed on conventional flow cytometers equipped with a typical configuration of lasers and optics. © 2023 The Authors. Current Protocols published by Wiley Periodicals LLC.Basic Protocol 1: Cell culture and metaphase harvest of suspension cell lineAlternate Protocol 1: Cell culture and metaphase harvest of adherent cell lineBasic Protocol 2: Preparation of chromosome suspension using polyamine isolation bufferBasic Protocol 3: Staining chromosomes with DAPI and propidium iodideAlternate Protocol 2: Staining chromosomes with Hoechst and Chromomycin A3Basic Protocol 4: Bivariate flow karyotyping on a cell analyzerBasic Protocol 5: Bivariate flow karyotyping on a cell sorterBasic Protocol 6: Purification of flow‐sorted chromosomes
Rectifying jet breakup by electric forcing
Authors: Van Assche David , Beneyton Thomas , Baret Jean‐Christophe 
Published: March 2023

AbstractThe high‐throughput production of monodisperse droplets is paramount in most of the applications in droplet microfluidics. In a flow‐focusing junction, a straightforward way to increase droplet production rate is to increase the flow rates. However, at a critical flow velocity, the droplet monodispersity breaks down due to a transition from the dripping to the jetting regime. As a result, a much more polydisperse droplet population is generated. The change from monodisperse to polydisperse droplet production emerges from the intrinsic properties of the instabilities of jets. In the jetting regime, droplet pinch‐off is governed by a convective instability which amplifies random noise when traveling down the jet leading to an irregular breakup. We show that with the use of an amplitude‐modulated electric signal, we select the breakup frequency of the jet. Matching the perturbation frequency close to the natural breakup frequency of the jet, we increase the monodispersity of the droplet population. This method is applicable to droplet production at a high throughput, that is, beyond the dripping to jetting threshold, including an active control since the frequency, and hence droplet sizes, are determined by the forcing frequency.
Post‐migratory nonbreeding movements of birds: A review and case study
Authors: Teitelbaum Claire S. , Bachner Natalie C. , Hall Richard J. 
Published: March 2023

AbstractSeasonal migrations are fascinating and ecologically important, but many migratory species are declining as climate change and land‐use change alter the habitats used by migrants across the annual cycle. While some migratory birds use a single wintering site, others undertake large‐scale post‐migratory movements during the nonbreeding season. Technological advances that enable tracking individual birds are uncovering more examples of post‐migratory nonbreeding movements. Documenting these movements is important for conservation, which requires understanding when and where migrants use habitats throughout their range. Here, we reviewed existing literature and collected information on the post‐migratory nonbreeding movements of 92 migratory bird species from 18 orders across six continents. Among these records, the most commonly reported drivers of movements were resource availability and climate. This strong dependence of post‐migratory nonbreeding movements on birds' abiotic and biotic environments suggests that environmental change will impact the patterns of these movements and potentially the fitness of species that undertake them. We also reviewed post‐migratory nonbreeding movements in North American‐breeding thrushes from the genus Catharus to examine the drivers of these movements in five closely related migratory species. We find that species that are less territorial are more likely to use multiple sites during the nonbreeding season; however, there is little evidence for dietary, evolutionary, or environmental differences between thrush species that move during winter and those that are stationary. While we believe our study represents the most comprehensive list of species exhibiting post‐migratory nonbreeding movements to date, biases in sampling, a lack of common terminology for these movements, and the still‐nascent availability of inexpensive, lightweight tracking devices mean that there are probably more populations that undertake such movements. Future research into the consequences of post‐migratory nonbreeding movements for individual fitness and ecosystem services would advance our understanding of their conservation importance and their evolution.
In‐situ Etching Synthesis of Defective CuBTC for CO2/CH4 Separation
Authors: Guo Biao , Xu Ruisong , Xu Ke , Liang Jing , Lu Jun , Wang Tonghua , Liu Jinxuan 
Published: March 2023

AbstractWe report a facile in‐situ etching method for the synthesis of defective CuBTC (H‐CuBTC) with hierarchical pore structure. The fabricated mixed matrix membranes (MMMs) containing H‐CuBTC was prepared for the separation of CO2/CH4, showing superior separation performance due to the defective structure with larger pore size and more open Cu sites, which enhance the interactions between H‐CuBTC and the polymer.
Metabolic Changes during Sprouting of Rapeseed and Their Consequences for the Volatilome of Cold‐Pressed Oil
Authors: Drabińska Natalia , Siger Aleksander , Jeleń Henryk H 
Published: March 2023

AbstractAll the procedures before pressing seeds have a great influence on the flavor of cold‐pressed rapeseed oil. However, the studies on the modification of aroma caused by inappropriate storage leading to sprouting are scarce. Therefore, this study aims to determine the effects of sprouting on the metabolome and volatilome of rapeseed cold‐pressed oil and press cakes. The presence of 56 and 21 nonvolatile metabolites is detected in seeds/press cakes and oil, respectively. Sprouting significantly affects the total contents of all groups of compounds, except sugars. At the same time, 375 volatile organic compounds (VOCs) are detected. The abundance of VOCs in sprouted oil is almost threefold higher compared to control oil, with the biggest contribution of sulfur‐containing compounds (dimethyl sulfide), glucosinolate derivatives (4‐isothiocyanato‐1‐butene), and aldehydes (3‐methylbutanal). A similar tendency is observed in press cake. Moreover, sprouting results in the biggest number of VOCs detected only in this oil (61). The abundance of aroma‐active compounds is much higher in sprouted products compared to corresponding controls, which has a confirmation in sensory analysis. This study shows that simultaneous volatilomics and metabolomics can be used to track the changes in the oil quality caused by the inappropriate storage of seeds. Sprouting leads to metabolic changes in seeds, which intensify the formation of new VOCs and consequently aroma of oils.Practical applications: The results of this study will help to understand the formation of volatile organic compounds (VOCs) during the processing and production of cold‐pressed rapeseed oil. The combination of VOCs with nonvolatile precursors can help to understand the pathways involved in VOCs formation. Moreover, the oil obtained from sprouted seeds is characterized by many VOCs not present in control oil, which can potentially be used to develop tools for quick evaluation if the seeds used for pressing initiated sprouting, which can lead to changes in its sensory quality.