bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nano‐Zinc Sulfide Modified 3D Reconstructed Zinc Anode with Induced Deposition Effect Assists Long‐Cycle Stable Aqueous Zinc Ion Battery
Authors: Guo Dongfang , Li Fengyu , Zhang Bin 
Published: January 2025

AbstractAqueous zinc ion batteries are often adversely affected by the poor stability of zinc metal anodes. Persistent water‐induced side reactions and uncontrolled dendrite growth have seriously damaged the long‐term service life of aqueous zinc ion batteries. In this paper, it is reported that a zinc sulfide with optimized electron arrangement on the surface of zinc anode is used to modify the zinc anode to achieve long‐term cycle stability of zinc anode. The effective active sites of the zinc metal anode surface are first significantly improved by a simple ultrasound‐assisted etching strategy, and then the in situ zinc sulfide interface phase further guides the zinc ion deposition behavior on the surface of the zinc metal anode. The zinc sulfide protective layer well regulates the interfacial electric field and the migration of Zn2+, thereby significantly promoting the homogenization of zinc ion flux to achieve dendrite‐free deposition. In addition, the aqueous zinc ion full cell assembled based on ZnS@3D‐Zn anode achieves better output performance in long‐term cycles. In summary, this work sheds light on the importance of reasonable interfacial modification for the development of dendrite‐free and stable zinc anode chemistry, which opens up a new path for promoting the development of zinc‐based batteries.
Short‐term outcomes of intracorporeal anastomosis in laparoscopic colectomy for colon cancer: A nationwide, multi‐institutional cohort study in Japan (ICAN study)
Authors: Yamaguchi Tomohiro , Tanaka Keitaro , Watanabe Jun , Hamamoto Hiroki , Nishimura Atsushi , Fujita Fumihiko , Suwa Hirokazu , Ito Masaaki , Kawai Kazushige , Hiro Junichiro , Yamamoto Seiichiro , Nambara Sho , Ota Masato , Ito Yuri , Okuda Junji , Inomata Masafumi , Watanabe Masahiko , Naitoh Takeshi ,   ICAN Collaborative Study Group of the Japan Society of Laparoscopic Colorectal Surgery
Published: January 2025

AbstractBackgroundSeveral randomized controlled trials and meta‐analyses have demonstrated the potential advantages of intracorporeal over extracorporeal anastomosis. However, the heterogeneity and small samples of these studies complicate drawing clear conclusions regarding such advantages. In this nationwide, multicenter, retrospective cohort study, we aimed to clarify the benefits of intracorporeal over extracorporeal anastomosis in patients undergoing laparoscopic colectomy for colon cancer.MethodsThis study included 46 institutions. Patients with clinical stage 0–III colon adenocarcinoma who underwent laparoscopic colectomy between January 2020 and December 2021 were evaluated. The effect of intracorporeal anastomosis on short‐term outcomes compared to extracorporeal anastomosis was assessed using propensity score matching.ResultsA total of 1245 patients (intracorporeal, n = 615; extracorporeal, n = 630) were included in the final analysis. The operative time was longer (228 vs. 207 min, p < 0.001), but blood loss was also lower (5.0 vs. 10.0 mL, p < 0.001) and the incidence of intraoperative vascular injury appeared lower (0.5% vs. 1.6%, p = 0.091) in the intracorporeal group than those in the extracorporeal group. The time to first passage of stool (2.9 vs. 3.5 days, p < 0.001) and length of hospital stay (9.3 vs. 10.2 days, p = 0.008) were shorter in the intracorporeal group.ConclusionsIntracorporeal anastomosis showed advantages over extracorporeal anastomosis in terms of blood loss, intraoperative vascular injury (potentially), bowel recovery, and length of hospital stay, despite the longer operative time.
An NIR‐II Absorbing Injectable Hydrogel for Boosted Photo‐Immunotherapy Toward Human Papillomavirus Associated Cancer
Authors: Yu Xinghua , Zeng Lingan , Yang Xinyue , Ren Zuliang , Dong Xuemei , Meng Ge , Shan Guogang , Yan Dingyuan , Wang Dong , Sun Fei 
Published: January 2025

ABSTRACTHuman papillomavirus (HPV) is a highly prevalent venereal pathogen accounting for genital warts and various cancers like cervical, anal, and oropharyngeal cancers. Although imiquimod, a topical medication, is commonly used to treat genital warts induced by HPV, its potential as an in situ immune response regulator for HPV‐related cancers has rarely been explored. In this study, we developed an innovative synergistic therapeutic platform by integrating near‐infrared‐II (NIR‐II) absorbing aggregation‐induced emission (AIE) agent (TPE‐BT‐BBTD) and imiquimod into an injectable hydrogel named TIH. TPE‐BT‐BBTD molecule that serves as a photothermal agent, with exposure to a 1064 nm laser, effectively destroys tumor cells and releases tumor‐related antigens. During the thermogenesis process, the hydrogel melts and releases imiquimod. The released imiquimod, in conjunction with the dead tumor antigens, stimulates dendritic cell maturation, activating the immune system to ultimately eliminate residual cancer cells. This novel approach combines the immunomodulatory effects of imiquimod with a 1064 nm‐excitable photothermal agent in a hydrogel delivery system, offering a promising tactic for combating HPV‐associated cancers.
Eosinophilic Granulomatosis With Polyangiitis: A Real‐World Study of Biologics and Sinus Surgery Use for Managing Nasal Polyposis
Authors: Kumar Nitish , Jett Savannah D. , Gomes Pedro Lança , Marino Michael J. , Miglani Amar , Lal Devyani 
Published: January 2025

ABSTRACTBackground/AimEosinophilic granulomatosis with polyangiitis (EGPA) is a multisystemic disease associated with nasal polyposis. Multiple biologics are used for managing EGPA, including some approved for nasal polyps (NP). This study investigated real‐world biologic prescription patterns for EGPA and their impact on NP and endoscopic sinus surgery (ESS) use.MethodsEGPA patients with NP treated with a biologic at any Mayo Clinic site (January 2010 to January 2024) were identified by querying the unified electronic medical record. Patterns of biologic therapy, clinical course, impact on NP, and performance of ESS were studied.ResultsEighty patients were identified. Overall, 71 of 80 (88.75%) patients underwent ESS, with 62 of 80 (77.5%) undergoing 131 ESS procedures prior to biologic therapy. ESS for recalcitrant NP (47 episodes) was performed on 38 of 80 (47.5%) patients on biologics. Biologic monotherapy was used in 90% (72) of patients; mepolizumab (81.9%) was the most common, followed by rituximab (23.6%), benralizumab (18.1%), and dupilumab (12.5%). Switching of biologics was observed in 28 of 80 patients. Concurrent dual‐biologic therapy was used in eight (10%) patients. For patients on single‐agent biologic therapy, ESS was performed on 52.5% of patients on mepolizumab, 23.5% on rituximab, 42.8% on benralizumab, and 22.2% on dupilumab.ConclusionsMultidisciplinary multi‐modality treatment with biologics and ESS appeared to be the mainstay of controlling NP in EGPA. Mepolizumab was the most frequently used biologic. Dual biologic therapy was necessary in 10% of patients. Overall, 71 of 80 (88.75%) patients had ESS, with almost half the study population (47.5%) undergoing ESS after initiating biologic treatment.
Effect of Graphene on the Mechanical Properties of Glycidyl Azide Polymer‐Based Energetic Thermoplastic Elastomer
Authors: Wang Teng , Liu Wenhao , Zhu Cong , Li Tianqi , Luo Yunjun 
Published: January 2025

ABSTRACTEnergetic adhesives with excellent mechanical properties are of great significance for the development of solid propellant. In this paper, a small amount of graphene is used to enhance the mechanical properties of glycidyl azide polymer (GAP)‐based energetic thermoplastic elastomer (GAP‐ETPE), and an in‐depth analysis of the graphene enhancement mechanism is conducted through the structural characterization of the composite elastomer. Scanning electron microscopy (SEM) reveals that the solvent‐assisted ultrasonic dispersion method can fully disperse graphene in GAP‐ETPE, taking advantage of its high specific surface area. Fourier Transform Infrared (FT‐IR) and low‐field Nuclear Magnetic Resonance (LF‐NMR) analysis show that graphene can provide physical crosslinking sites, significantly increasing the crosslinking density of GAP‐ETPE. Dynamic mechanical analysis (DMA) indicates that the increased crosslinking density caused by graphene will restrict the segmental motion of GAP‐ETPE. Static tensile test result shows that the use of 0.1 wt% graphene can increase the tensile strength of GAP‐ETPE from 7.0 to 7.8 MPa. This work provides a basis for the application of graphene in energetic adhesives.
A Type of Low‐Temperature Resistant Material Based on Ethylene Propylene Monomer/Polypropylene Thermoplastic Vulcanizates Compatibilized by Polyisobutylene
Authors: Li Rui , Zhang Xinru , Hou Yanbing , Wang Rui , Han Jingjie 
Published: January 2025

ABSTRACTThermoplastic vulcanized rubber (TPV) result in intermaterial incompatibility due to the thermodynamic incompatibility of the components that make up their soft and hard segments, which results in significant low‐temperature brittleness and poor mechanical properties of the material. And the low‐temperature properties of thermoplastic elastomers, especially based on ethylene propylene monomer/polypropylene (EPDM/PP) thermoplastic elastomers, and the corresponding mechanism of action have not been elucidated. The balance between low temperature performance and mechanical properties is a real challenge for TPV. In this paper, polyisobutylene (PIB1300) was introduced into the interstices of the molecular chain as an adhesive plasticizer to enhance the interfacial adhesion between PP and EPDM. The torque change showed that the presence of PIB1300 increased the interfacial interaction between PP and EPDM. The contact angle test and the calculation of the compatibilizer's position of action further confirmed that PIB1300 could be used as an effective compatibilizer to improve the compatibility of the material. When the amount of PIB1300 was 3 phr, EPDM/PP with both mechanical properties and compatibility, low temperature resistance, low temperature elasticity, and low temperature brittleness was finally determined, and the tensile strength of the material was 12.34 MPa, which was by 109.86%.
Effect of Mussel‐Inspired Polydopamine Functionalized Hydroxyapatite on the Properties of Natural Rubber Latex Films
Authors: Gong He , Jiang Guangzhen , Zhong Kai , Wang Zhifen , Fang Lin 
Published: January 2025

ABSTRACTImproving the strength and oxidation resistance of natural latex films and reducing the water‐soluble protein content are essential for the preparation of high‐quality multifunctional natural rubber latex (NRL) products. Hydroxyapatite (HA) has received much attention as a biocompatible material for its unique protein adsorption properties, but its poor compatibility with NRL has resulted in compromised results. Therefore, in this work, HA was modified by dopamine with excellent adhesion properties of OH and NH2‐rich to improve the compatibility of HA with rubber matrix. Therefore, the present work utilizes the excellent adhesion property of dopamine (PDA) to adsorb onto the HA surface through π–π interactions. The HA was then functionalized to obtain modified HA (HA‐PDA), which improves the compatibility between natural latex and HA, enhances the physical and mechanical properties, antioxidant properties, and reduces the water‐soluble protein content of natural latex films. When 0.18 wt% HA‐PDA was added, the tensile and tear strengths of the composite film increased by 32.4% and 42.92%, respectively, compared to the natural latex film. After 36 h of aging, the HA‐PDA/NRL adhesive film still has 35.92% tensile strength retention compared to commercial antioxidant 246. Moreover, the water‐soluble protein dissolved in HA‐PDA/NRL vulcanized films was only 15.05 μg/g, which was 67.49% lower than that of NRL. In addition, good biocompatibility of the composite adhesive film was also demonstrated by cytotoxicity experiments, which provides a new method for the preparation of high‐strength, strong antioxidant, hypoallergenic, and good biocompatible latex products.
Lipocalin‐2 Determination on Multiwalled Carbon Nanotube Integrated Circular Electrodes for Diagnosing Ulcerative Colitis
Authors: Qiao Guangchao , Sheng Jijian 
Published: January 2025

ABSTRACTUlcerative colitis affects the inner lining of the large intestine, causing discomfort, pain, and digestion issues, and sometimes leading to life‐threatening complications. With proper medication, symptoms and inflammation can be reduced, improving the condition. In this research, a multiwalled carbon nanotube (MWCN)‐modified circular interdigitated electrode (circular‐IDE) biosensor was developed to detect the ulcerative colitis biomarker lipocalin‐2 and measured at 0–2 V. A dual probing strategy with aptamer and antibody on gold nanoparticles was employed for the detection of lipocalin‐2. Probe immobilization was optimized on MWCN‐modified circular‐IDE, and saturation of 800 nM of aptamer on the GNP‐antibody facilitated the identification of lipocalin‐2 at concentrations as low as 1 pg/mL, with an R2 value of 0.9716 [y = 2.1058x − 2.7351]. Furthermore, lipocalin‐2 spiking in serum increased the current responses in correlation with the concentrations of lipocalin‐2, indicating selective identification without interference. In addition, nonimmune antibody and GNP‐conjugated complementary aptamer did not increase the current responses, affirming the specific detection of lipocalin‐2. This MWCN‐modified circular‐IDE biosensor, utilizing aptamer–antibody interactions, aids in identifying the condition of ulcerative colitis.
The mediating role of student engagement in the relationship between teacher and digital support and learner satisfaction in blended learning environments at higher education
Authors: Kok Xiao‐Feng Kenan , Pua Ching Yee , Puah Shermain , Devilly Oran Zane , Wang Peng Cheng , Chua Eric Chern‐Pin 
Published: January 2025

AbstractGiven the emergence of blended learning as the dominant mode of learning at university in a post‐COVID‐19 world, the need to examine students' perceptions of blended learning is increasingly becoming more important. This study examined the mediating role of student engagement in the relationship between the types of support (i.e., teacher, digital) and learner satisfaction in blended learning environments. A sample of 674 Year 1 and Year 2 students from a public university in Singapore participated in this study. Structural equation modelling showed that (1) teacher autonomy and digital relatedness support predicted agentic engagement, (2) digital competence and relatedness support predicted emotional engagement, (3) emotional engagement predicted all learner satisfaction facets except for learner–instructor interaction and (4) agentic engagement predicted all learner satisfaction facets except for learner–technology interaction. Of the four dimensions of student engagement, only emotional and agentic engagement mediated the relationships between various dimensions of support and learner satisfaction. Overall, these findings highlight the importance of emotionally engaging students and imbuing a sense of agency in them to enhance the relationships between the types of support and learner satisfaction.
Successful Treatment of Large Left Ventricular Thrombosis During Extracorporeal Membrane Oxygenation (ECMO): A Case Report and Review of the Literature
Authors: Yang Xue‐ting , Chen Yi‐jin , Zeng Han , Deng Lei , Chang Li , Li Yi , Song Meng‐long , Zhang Yang , Peng Wei , Wang Dong , Jiang Hua , Peng Hong‐qiong 
Published: January 2025

ABSTRACTWe report a rare complication of left ventricular giant thrombus in a patient with fulminant myocarditis after venoarterial extracorporeal membrane oxygenation therapy. This case report offers simple anticoagulant treatment experiences to eliminate significant LV thrombosis in patient undergoing extracorporeal membrane oxygenation, so that patients do not need surgery.
Giant Hydatid Cyst Originating From Psoas Muscle Extending to the Iliac Bone: A Case Report
Authors: Niakan Mohammad Hadi , Mirparsa Fatemeh , Arani Hamid Zaferani , Hooshmandi Sedighe , Peyravi Elham 
Published: January 2025

ABSTRACTHydatid cysts, caused by the Echinococcus granulosus parasite, predominantly affect the liver and lungs, but can also impact other organs such as the kidneys, brain, and muscles. Infection occurs when individuals ingest eggs from contaminated food or water, leading to cyst formation primarily in the liver. While hydatid cysts are commonly found in various endemic regions, muscular involvement is rare, particularly in the psoas muscle. This report presents a case of a muscular hydatid cyst, describes its management, and emphasizes the need for awareness and prompt intervention. A 50‐year‐old man presented with abdominal and left lower limb pain, along with weakness over several days. He was febrile, and a physical examination revealed pain during leg movement. Routine laboratory tests were normal. Ultrasound and computed tomography scans identified a solid cystic mass in the left lower quadrant, extending to the left lumbar muscle. After 28 days of preoperative albendazole therapy, the patient underwent surgery through a Rocky Davis incision, where a large hydatid cyst containing daughter cysts in the psoas muscle was discovered. The cyst was unroofed, and its contents were evacuated, followed by irrigation with hypertonic saline. Postoperative recovery was uneventful. He also received standard medication therapy with albendazole, and during monthly visits, no complications were observed during the one‐year follow‐up. This case contributes to the limited literature on muscular hydatid disease and highlights the importance of awareness among healthcare providers to ensure timely diagnosis and management.
Carbon Monoxide Toxicity Secondary to Cutaneous Methylene Chloride Exposure: A Case Report
Authors: Dornbush Carine , Mohr William , Galet Colette , Wibbenmeyer Lucy , Kurjatko Alexander 
Published: January 2025

ABSTRACTCutaneous absorption of methylene chloride is rarely toxic. This case shows that it can lead to carboxyhemoglobinemia. Exposure to methylene chloride should warrant a carboxyhemoglobin check and oxygen support. Adequate decontamination and monitoring for symptoms in patients with greater cutaneous exposure due to persistent risks for toxicity are warranted.
Through‐Space Charge Transfer Dynamic Mechanism in V‐Shaped Flexible Carbazole Aromatic Imides Dyads
Authors: Yang Yuhang , Li Yang , Jing Rui , Situ Zicong , Kong Jie , Zhou Meng , Zhao Hongmei , Wan Yan , Xia Andong , Kuang Zhuoran 
Published: January 2025

AbstractCofacial electron donor‐acceptor dyads exhibiting through‐space charge‐transfer (TSCT) characteristics are widely employed in the development of optoelectronic functional materials. The flexible molecular frameworks between the electron donor and acceptor components allow dynamic modulation of electronic coupling, influenced by excited‐state structural relaxation or intermolecular interactions, thereby affecting the charge‐transfer (CT) dynamics and the emission properties of TSCT states. In this work, we examine the TSCT dynamic processes of two electron donor‐acceptor dyads, CzPhNI and CzPhPI formed by ortho‐substitution of phenyl linkage with V‐shaped flexible TSCT structures using carbazole as donor and naphthalimide or phthalimide as acceptor. A pseudo‐cofacial TSCT conformation formed in the excited state effectively shortens the donor‐acceptor distance and enhances CT coupling. Femtosecond spectroscopy reveals an ultrafast TSCT kinetics in the (200 fs)−1 timescale. Moreover, the intermolecular interaction‐induced D−A stacking further strengthens the electronic coupling, accelerating the TSCT reaction rate from (2.07 ps)−1 to (174 fs)−1 as solution concentrations increases from 10−5 to 10−3 M. The results obtained in this work offers valuable physical insights into the TSCT dynamic mechanism, potentially explaining the widely observed emission enhancement in weakly‐coupled, flexible TSCT emitters transitioning from solution to aggregation states.
Progress and Future Challenges in Designing High‐Performance Ni/CeO2 Catalysts for CO2 Methanation: A Critical Review
Authors: Liu Kun , Nawaz Muhammad Asif , Liao Guangfu 
Published: January 2025

ABSTRACTThe Ni/CeO2 catalyst stands out among various solid metal oxide catalysts for its exceptional catalytic proficiency, positioning it as a prime candidate for the industrialization of methanation processes. This review thoroughly examines the prevalent challenges associated with Ni/CeO2 in methanation reactions, compiles current strategies to overcome these hurdles, and presents novel perspectives. The review elucidates the structural characteristics of Ni/CeO2 and its applications in catalytic reactions, discusses various synthesis methods and their respective merits and demerits, explores catalytic reaction systems at both laboratory and industrial scales, and clarifies the underlying reaction mechanisms. Furthermore, it underscores the mainstream approaches to enhance the low‐temperature activity of Ni/CeO2 in methanation and to mitigate activity decrement due to Ni agglomeration. The review concludes by proposing future directions for improving low‐temperature methanation activity and preventing catalyst deactivation, encompassing the development of innovative catalyst architectures, integrating in‐situ characterization with theoretical calculations, and investigating photothermal methanation catalytic systems. Undoubtedly, scientific researchers will persistently strive to develop Ni/CeO2 catalysts with high activity across a broad temperature range and robust stability, driving the industrialization of CO2 methanation technology in the foreseeable future.
Can a Cochlear Implant Be Used as an Electrical Impedance Tomography Device?
Authors: Fourie Friedemarie , Thiselton Joshua , Hanekom Tania 
Published: January 2025

ABSTRACTThe imaging of the live cochlea is a challenging task. Regardless of the quality of images obtained from modern clinical imaging techniques, the internal structures of the cochlea mainly remain obscured. Electrical impedance tomography (EIT) is a safe, low‐cost alternative medical imaging technique with applications in various clinical scenarios. In this article, EIT is investigated as an alternative method to image and extract the centre of gravity of the modiolus in vivo. This information can be used to augment present postoperative medical imaging techniques to investigate the cochlea. The cochlear implant EIT system was simulated by modelling user‐specific electrode array trajectories within a simple conductive medium containing an inhomogeneity representing the modiolus. The method included an adapted adjacent stimulation protocol for data collection. For the image reconstruction, NOSER and Tikhonov priors were considered. A parameter analysis was conducted to find the most robust combination of image priors and hyperparameters for this application. The cochlear implant EIT methodology was validated at different noise levels for four electrode array trajectories. Comparing the NOSER and Tikhonov priors, it was observed that the NOSER prior exhibits superior centre of gravity localisation performance in cochlear implant EIT image reconstruction for different noise levels and user‐dependent variability in electrode array trajectories. Image reconstruction, using a NOSER prior at a hyperparameter value of approximately 0.001, resulted in an average centre of gravity localisation error of less than 4% for all electrode array trajectories using difference imaging and less than 5.5% using absolute imaging.