bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reinstatement of Previously Deregistered Health Professionals in Australia: Legal Determinations of Risk, Patient Safety, and Public Interest
Authors: Millbank Jenni 
Published: February 2023

AbstractEach year approximately 60 registered health practitioners in Australia have their registration cancelled for reasons of serious misconduct or, less commonly, impairment or criminal conviction. Cancellation remains in force unless the practitioner successfully brings a later application to be restored to the register. While the decision to deregister takes place in a public tribunal process, with published reasons, throughout most of Australia determinations concerning reinstatement are undertaken by professional Boards in private. This research examines available reinstatement decisions concerning 86 health practitioners to analyse how the health regulatory system in Australia determines questions of public interest and public safety when deciding whether deregistered health practitioners who seek reinstatement are now ‘fit and proper’ to practise their profession again. There is a considerable body of case law on the meaning of fitness to practise for health professionals, and the process by which it can be assessed. However, there is remarkably little legislative content or administrative guidance to structure the reinstatement inquiry, assist applicants in the process or to ensure consistency of decision-making, in particular by drawing attention to broader public protection factors. Reinstatement determinations would be improved through the introduction of structured guidance on how to apply the paramount objective of public protection. The article also suggests that having all reinstatement determinations take place in public with published reasons would improve public understanding of, and confidence in, the reinstatement process.
Technical-economic study of PVC-based formulations intended to industrial 3-wire electric cables, using a full factorial design methodology
Authors: CHERFI Abdelhamid , DEHAK-OUGHLISSI Karima , BALI Sid-Ali , MEDDOUR Touhami BEN 
Published: February 2023

In the present study, full factorial designs were used to model and optimize the mechanical properties of PVC-based formulations constituting three-core power cables: sheathing, insulation and stuffing, while respecting the standards in force, and aiming for a minimum cost. The effects of 4 parameters: plasticizer content (X1), filler content (X2), stabilizing agent content (X3) and the kind of plasticizer were investigated on the following properties: Density (D), Hardness (H), Elongation at break (EB) and Fracture resistance (FR), as well as the price (DA/kg of formulation). The desirability-based optimization gave the following values: EB = 214.72%, FR = 19.94 MPa and Price = 116.71 DA/kg for the sheathing; EB = 198.11%, FR = 4.38 MPa and Price = 61.73 DA/kg for the stuffing; EB = 207.84%, FR = 19.35 MPa and Price = 102.73 DA/kg for the insulation. The study revealed also that the order of significance of the effects on the mechanical properties was: X1>X2>X3 and that the use of cheapest plasticizer did not affect greatly the mechanical properties.
Internal student migration in India: Impact of the COVID-19 crisis
Authors: Singh Rajni , Manchanda Navneet , Mishra Rakesh 
Published: February 2023

The education sector in India was among the most affected sectors during the COVID-19 pandemic. While considerable attention has been paid to informal workers' return or reverse migration to their home communities, not much has been reported about the challenges faced by migrant students. Using a mixed-method approach, the current study presents an overview of internal student migration in India prior to the COVID-19 pandemic using data from the 2001 and 2011 Census of India and the 2007–2008 National Sample Survey Organization, and discusses challenges faced by selected migrant learners during the COVID-19 pandemic based on primary research. Based on the census data, nearly 3.3 million migrants in India move for study reasons with 2.9 million migrating within the state (with the duration of residence less than five years) from their last residence within India. The pattern of female student migration suggests an increasingly localized interdistrict migration. Findings from the qualitative data indicate that during the pandemic, students had compromised learning and placement experience, inadequate digital resources and pressure to repay loans. Student migrants experienced varying degrees of the impact of the COVID-19 pandemic based on their destination and migration stream.
Strategies of Total Auricular Reconstruction for Patients With Poor Skin Coverage at the Mastoid Area
Authors: Gao Dejin , Chen Xueying , Sun Qing , Huang Yue , Li He , Zhang Mingyu , Li Jingjing , Liu Tun , Wang Bingqing 
Published: February 2023

Objective Burns and injuries can lead to massive defects in the mastoid tissues, which increase the difficulty of ear reconstruction. It is crucial to choose an appropriate surgical method for these patients. Here, we introduce strategies for auricular reconstruction in patients without satisfactory mastoid tissues. Methods From April 2020 to July 2021, 12 men and 4 women were admitted to our institution. Twelve patients were severely burned, 3 patients experienced car accidents, and 1 patient had a tumor on his ear. The temporoparietal fascia was used for ear reconstruction in 10 cases, and the upper arm flap was used in 6 cases. All of the ear frameworks were made of costal cartilage. Results The location, size, and shape of both sides of the auricles were generally the same. Two patients needed further surgical repair because of cartilage exposure at the helix. All of the patients were satisfied with the outcome of the reconstructed ear. Conclusion For patients with ear deformity and poor skin coverage in the mastoid area, we can choose the temporoparietal fascia if the patient’s available superficial temporal artery is longer than 10 cm. If not, we can choose the upper arm flap. The latter needs a five-stage operation, which is more time consuming and difficult than the former. Moreover, the expanded upper arm flap is thinner and has better elasticity than the temporoparietal fascia, so the shape of the reconstructed ear is better. We need to evaluate the condition of the affected tissue and choose the appropriate surgical method to achieve a good result.
Safety outcomes of anti-platelet therapy post coronary artery bypass graft surgery: A systematic review and network meta-analysis of randomized control trials
Authors: Hasan Syed U , Pervez Alina , Shah Arshad A , Shah Syed DA , Aslam Muhammad , Arshad Anosha , Rajput Amna S , Zubair M. Mujeeb 
Published: February 2023

Background Antiplatelet therapy is used to decrease the risk of graft failure post coronary artery bypass graft surgery. We aimed to compare dual antiplatelet therapy (DAPT) with monotherapy along with a comparison of Aspirin, Ticagrelor, Aspirin+Ticagrelor (A+T) and Aspirin+Clopidogrel (A+C) to determine the major and minor bleeding risk, risk of postoperative myocardial infarction (MI), stroke, and all-cause mortality (ACM). Methods Randomized Controlled Trials comparing the four groups were included. Odds ratio (OR) and Absolute Risk (AR) were employed to assess the mean and standard deviation (SD) with 95% confidence intervals (CI). The Bayesian random-effects model was used for statistical analysis. Risk difference and Cochran Q tests were used to calculate rank probability (RP) and heterogeneity, respectively. Results We included 10 trials, consisting of 21 arms and 3926 patients. For the risk of major and minor bleed, A + T and Ticagrelor showed the lowest mean value of 0.040 (0.043) and 0.067 (0.073), respectively, and the highest RP of being the safest group. While a direct comparison between DAPT and monotherapy resulted in an OR of 0.57 [0.34, 0.95] for the risk of minor bleed. A + T was found to have the highest RP and the lowest mean value in terms of ACM, MI, and stroke. Conclusion No significant difference was found between monotherapy or dual-antiplatelet therapy for the major bleeding risk safety outcome, however DAPT was found to have a significantly higher rate of minor bleeding complications post-CABG. DAPT should be considered as the antiplatelet modality of choice post-CABG.
Development of a nomogram for severe influenza in previously healthy children: a retrospective cohort study
Authors: Huang Wenyun , Niu Wensi , Chen Hongmei , Jiang Wujun , Fu Yanbing , Li Xiuxiu , Li Minglei , Hua Jun , Hu Chunxia 
Published: February 2023

Objective We aimed to develop a nomogram to predict the risk of severe influenza in previously healthy children. Methods In this retrospective cohort study, we reviewed the clinical data of 1135 previously healthy children infected with influenza who were hospitalized in the Children's Hospital of Soochow University between 1 January 2017 and 30 June 2021. Children were randomly assigned in a 7:3 ratio to a training or validation cohort. In the training cohort, univariate and multivariate logistic regression analyses were used to identify risk factors, and a nomogram was established. The validation cohort was used to evaluate the predictive ability of the model. Result Wheezing rales, neutrophils, procalcitonin > 0.25 ng/mL, Mycoplasma pneumoniae infection, fever, and albumin were selected as predictors. The areas under the curve were 0.725 (95% CI: 0.686–0.765) and 0.721 (95% CI: 0.659–0.784) for the training and validation cohorts, respectively. The calibration curve showed that the nomogram was well calibrated. Conclusion The nomogram may predict the risk of severe influenza in previously healthy children.
Two Novel Clinical Tests for the Diagnosis of Hip Labral Tears
Authors: Adib Farshad , Hartline Jacob , Donovan J. Skye , Kalachi Kourosh , Dehghan Pegah , Ochiai Derek 
Published: February 2023

Background: There are few well-studied clinical tests for the diagnosis of hip labral tears. As the differential diagnosis for hip pain is broad, accurate clinical examination is important in guiding advanced imaging and identifying patients who may benefit from surgical management. Purpose: To determine the diagnostic accuracy of 2 novel clinical tests for the diagnosis of hip labral tears. Study Design: Cohort study (diagnosis); Level of evidence, 2. Methods: Clinical examination findings including the Arlington, twist, and flexion-adduction-internal rotation (FADIR)/impingement tests as performed by a fellowship-trained orthopaedic surgeon specializing in hip arthroscopy were obtained from retrospective chart review. The Arlington test ranges the hip from flexion-abduction-external rotation to FADIR while applying subtle internal rotation and external rotation motion. The twist test involves internal rotation and external rotation of the hip while weightbearing. Diagnostic accuracy statistics for each of the tests were calculated using magnetic resonance arthrography as the reference standard. Results: A total of 283 patients were included in the study with a mean age of 40.7 years (range, 13-77 years) and 66.4% were women. The Arlington test was found to have a sensitivity of 0.94 (95% CI, 0.90-0.96), specificity of 0.33 (95% CI, 0.16-0.56), positive predictive value (PPV) of 0.95 (95% CI, 0.92-0.97), and negative predictive value (NPV) of 0.26 (95% CI, 0.13-0.46). The twist test was found to have a sensitivity of 0.68 (95% CI, 0.62-0.73), specificity of 0.72 (95% CI, 0.49-0.88), PPV of 0.97 (95% CI, 0.94-0.99), and NPV of 0.13 (95% CI, 0.08-0.21). The FADIR/impingement test was found to have a sensitivity of 0.43 (95% CI, 0.37-0.49), specificity of 0.56 (95% CI, 0.34-0.75), PPV of 0.93 (95% CI, 0.87-0.97), and NPV of 0.06 (95% CI, 0.03-0.11). The Arlington test was significantly more sensitive than both the twist and FADIR/impingement tests ( P < .05), while the twist test was significantly more specific than the Arlington test ( P < .05). Conclusion: The Arlington test is more sensitive than the traditional FADIR/impingement test, while the twist test is more specific than the FADIR/impingement test in diagnosing hip labral tears in the hands of an experienced orthopaedic surgeon.
A Knitted PET Patch Enhances the Maturation of Regenerated Tendons in Bridging Reconstruction of Massive Rotator Cuff Tears in a Rabbit Model
Authors: Zhong Yuting , Jin Wenhe , Gao Han , Sun Luyi , Wang Peng , Zhang Jian , Ong Michael Tim Yun , Sai Chuen Bruma Fu , Chen Shiyi , Chen Jun 
Published: February 2023

Background: Although nondegradable synthetic grafts for bridging reconstruction of massive rotator cuff tears (MRCTs) have shown satisfactory clinical outcomes, their function and details on graft-tendon healing and enthesis regeneration have not been fully studied. Hypothesis: The knitted polyethylene terephthalate (PET) patch as a nondegradable synthetic graft could provide sustained mechanical support, facilitating enthesis and tendon regeneration in the treatment of MRCTs. Study Design: Controlled laboratory study. Methods: A knitted PET patch was fabricated for bridging reconstruction (PET group) in a New Zealand White rabbit model of MRCTs (negative control group), and an autologous Achilles tendon was used as a control (autograft group). The animals were sacrificed, and tissue samples were harvested for gross observation as well as histological and biomechanical analyses at 4, 8, and 12 weeks postoperatively. Results: Histological analysis showed no significant difference in the graft-bone interface score between the PET and autograft groups at 4, 8, and 12 weeks postoperatively. Interestingly, in the PET group, Sharpey-like fibers were observed at 8 weeks, while fibrocartilage formation and the ingrowth of chondrocytes were recognized at 12 weeks. Meanwhile, the tendon maturing score was significantly higher in the PET group than in the autograft group (19.7 ± 1.5 vs 15.3 ± 1.2, respectively; P = .008) at 12 weeks, with parallel-oriented collagen fibers around the knitted PET patch. Moreover, the ultimate failure load of the PET group was similar to that of a healthy rabbit tendon at 8 weeks (125.6 ± 13.6 vs 130.8 ± 28.6 N, respectively; P > .05) and no different from that of the autograft group at 4, 8, and 12 weeks. Conclusion: The knitted PET patch could not only immediately reconstruct the mechanical support for the torn tendon postoperatively in the rabbit model of MRCTs but also enhanced maturation of the regenerated tendon by fibrocartilage formation and improved the organization of collagen fibers. Herein, the knitted PET patch could be a promising candidate graft adopted in bridging reconstruction of MRCTs. Clinical Relevance: A nondegradable knitted PET patch can safely bridge MRCTs with satisfactory mechanical strength and the promotion of tissue regeneration.
Predictors of Return to Work Following Primary Arthroscopic Rotator Cuff Repair: An Analysis of 1502 Cases
Authors: Ting Ryan S. , Rosenthal Ron , Shin Yaerhim , Shenouda Mina , Al-Housni Hilal S. A. , Lam Patrick H. , Murrell George A. C. 
Published: February 2023

Background: It is undetermined which factors predict return to work after arthroscopic rotator cuff repair. Purpose: To identify which factors predicted return to work at any level and return to preinjury levels of work 6 months after arthroscopic rotator cuff repair. Study Design: Case-control study; Level of evidence, 3. Methods: Multiple logistic regression analysis of prospectively collected descriptive, preinjury, preoperative, and intraoperative data from 1502 consecutive primary arthroscopic rotator cuff repairs, performed by a single surgeon, was performed to identify independent predictors of return to work at 6 months postoperatively. Results: Six months after arthroscopic rotator cuff repair, 76% of patients had returned to work, and 40% had returned to preinjury levels of work. Return to work at 6 months was likely if patients were still working after their injuries but before surgery (Wald statistic [W] = 55, P < .0001), were stronger in internal rotation preoperatively (W = 8, P = .004), had full-thickness tears (W = 9, P = .002), and were female (W = 5, P = .030). Patients who continued working postinjury but presurgery were 1.6 times more likely to return to work at any level at 6 months compared to patients who were not working ( P < .0001). Patients who had a less strenuous preinjury level of work (W = 173, P < .0001), worked at a mild to moderate level post injury but presurgery, had greater preoperative behind-the-back lift-off strength (W = 8, P = .004), and had less preoperative passive external rotation range of motion (W = 5, P = .034) were more likely to return to preinjury levels of work at 6 months postoperatively. Specifically, patients who worked at a mild to moderate level postinjury but presurgery were 2.5 times more likely to return to work than patients who were not working, or who were working strenuously postinjury but presurgery ( p < 0.0001). Patients who nominated their preinjury level of work as “light” were 11 times more likely to return to preinjury levels of work at 6 months compared to those who nominated it as “strenuous” ( P < .0001). Conclusion: Six months after rotator cuff repair, patients who continued to work after injury but presurgery were the most likely to return to work at any level, and patients who had less strenuous preinjury levels of work were the most likely to return to their preinjury levels of work. Greater preoperative subscapularis strength independently predicted return to work at any level and to preinjury levels.
Exploring the Mechanism of Microfracture in the Treatment of Porcine Full-Thickness Cartilage Defect
Authors: Li Hui , He Zihao , Li Wenjing , Yao Jiaying , Lyu Cheng , Du Yanan , Xing Dan , Lin Jianhao 
Published: February 2023

Background: Microfracture has the most extensive clinical application because of its advantages of a single operation, unified process, and low operation cost. Because research on the repair mechanism of microfractures in the treatment of cartilage defects is not in-depth, this study aimed to elucidate the mechanism. Purpose: To identify the characteristic cell subsets at different repair stages after microfracture, systematically analyze the repair process of the defect area after microfracture, and investigate the mechanism of fibrocartilage repair. Study Design: Descriptive laboratory study. Methods: Full-thickness articular cartilage defects and microfractures was established in the right knee of Bama miniature pigs. Single-cell transcriptional assays were used to identify the characteristics of cells isolated from healthy articular cartilage and regenerated tissues. Results: Microfractures induced mature fibrous repair in the full-thickness cartilage defect six months after surgery, while early stages of repair occurred within six weeks. Based on single-cell sequencing results, eight subsets and specific marker genes were identified. Two processes may occur after microfracture: normal hyaline cartilage regeneration and abnormal fibrocartilage repair. Regulatory chondrocytes, proliferative chondrocytes and cartilage progenitor cells (CPCs) may play important roles in the normal regeneration process. During abnormal repair, CPCs and skeletal stem cells may have different functions, and macrophages and endothelial cells may play important regulatory roles in the formation of fibrochondrocytes. Conclusions: Using single-cell transcriptome sequencing, this study investigated the tissue regeneration process and identified key cell subsets after microfracture. Clinical Relevance: These results provide future targets for optimizing the repair effect of microfracture.
Telehealth-supervised exercise in systemic lupus erythematosus: A pilot study
Authors: Frade Stephanie , O’Neill Sean , Walsh Samantha , Campbell Chloe , Greene David , Bird Stephen P. , Cameron Melainie 
Published: February 2023

Objectives To explore the feasibility and effectiveness of telehealth-supervised exercise for adults with Systemic lupus erythematosus (SLE). Methods This was a non-randomised controlled pilot trial comparing telehealth-supervised exercise (8 weeks, 2 days/week, 45 min, moderate intensity) plus usual care with usual care alone. Mixed methods were used to assess change in fatigue (FACIT-fatigue), quality of life (SF36), resting fatigue and pain (11-point scale), lower body strength (five-time sit-to-stand) and endurance (30 s sit-to-stand), upper body endurance (30 s arm curl), aerobic capacity (2 min step test), and experience (survey and interviews). Group comparison was performed statistically using a two-sample T-test or Mann–Whitney U-test. Where known, we used MCID or MCII, or assumed a change of 10%, to determine clinically meaningful change within groups over time. Interviews were analysed using reflexive thematic analysis. Results Fifteen female adults with SLE were included (control group n = 7, exercise group n = 8). Statistically significant differences between groups, in favour of the exercise intervention, were noted for SF36 domain emotional well-being ( p = 0.048) and resting fatigue ( p = 0.012). There were clinically meaningful improvements over time for FACIT-fatigue (+6.3 ± 8.3, MCID >5.9), SF36 domains physical role functioning (+30%), emotional role functioning (+55%), energy/fatigue (+26%), emotional well-being (+19%), social functioning (+30%), resting pain (−32%), and upper body endurance (+23%) within the exercise group. Exercise attendance was high (98%, 110/112 sessions); participants strongly agreed ( n = 5/7, 71%) or agreed ( n = 2/7, 29%) they would do telehealth-supervised exercise again and were satisfied with the experience. Four themes emerged: (1) ease and efficiency of exercising from home, (2) value of live exercise instruction, (3) challenges of exercising at home, and (4) continuation of telehealth-supervised exercise sessions. Conclusion Key findings from this mixed-method investigation suggest that telehealth-supervised exercise was feasible for, and well-accepted by, adults with SLE and resulted in some modest health improvements. We recommend a follow-up RCT with more SLE participants.
Application of Mobile-Based Games in The Rehabilitation of Stroke Survivors
Authors: Norouzkhani Narges , Hamednia Mahsa , Aalaei Shokoufeh 
Published: February 2023

Background Stroke, as a cerebral vascular accident, leads to brain injury which is characterized by interrupted blood flow. Indeed, impairments in the face, arms, and speech are usual symptoms of a stroke. A variety of disorders emerges after stroke, specific rehabilitation programs are used to restore the lost functions and improve the health status of the patient, mainly if they are applied early. In this study, we tried to present a comprehensive appraisal of recent findings and innovations in mobile games intended for the rehabilitation of stroke survivors. Methods Using keywords of interest including rehabilitation, stroke, mobile/computer, and application/game, a thorough search was performed in PubMed, Scopus, and Embase. Retrieved papers were scrutinized based on predefined inclusion and exclusion criteria. Results Unfortunately, due to the limitations in the resources and facilities, early rehabilitation is not feasible in most cases. However, mobile technology is a promising avenue to address this hurdle, substantiating in the early rehabilitation practices in stroke patients. Mobile games hopefully brings a bunch of valuable outcomes and benefits, such as innovation, low-cost, and exciting approaches, both in clinical and home settings. Indeed, mobile devices save time, which could be spent to improve fine motor functions, leading to the acceleration of treatment for patients who are at home after discharge from hospitals. Conclusion Acceptable motor improvement, visual perception, cognition, quality of life, satisfaction, and preferences of the patients are essential factors that should be considered in the design of these applications. It was shown that conventional strategies combined with such modern computer-based technologies might have synergistic effects on restoring the lost skills in stroke patients.