bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dynamic analysis of a fuzzy Bobwhite quail populations Model
Authors: Ouyang Miao , Zhang Qianhong 
Published: September 2023

Abstract
This paper concerns a kind of fuzzy third-order nonlinear difference equation $$ x_{n+1}=A+Bx_n+\frac{x_n}{x_{n-1}x_{n-2}},\ \ n=0,1,\cdots,$$from the Bobwhite quail population model, where the parameters $A,B$ and initial values $x_i (i=-2,-1,0)$ are positive parabolic fuzzy numbers. According to g-division of fuzzy sets and based on the symmetrical parabolic fuzzy numbers, the conditional stability of this model is proved, besides the existence, boundedness and persistence of its unique positive fuzzy solution. Then, the relative Allee effect analysis is done by contrasting the Zadeh extension principle with g-division. The extinction thresholds with fuzzy degree is illustrated. As a Supplement, several numerical examples and table are interspersed to illustrate the effectiveness.
MSC: 39A10
Evaluation of the feeding safety of Moringa (Moringa oleifera L.)
Authors: Zhang Yu-Wen , Wang Fu-Jun , Cai Ming , Liu Yan-Pei , Liu Jian-Yong , Huang Bi-Zhi 
Published: September 2023

Abstract

This study aimed to evaluate the safety of Moringa by comparing the effects of different gavage doses of Moringa.The general behavior, body weight, food intake, blood indexes, serum biochemical indexes, and histopathology of rats were used to determine the safety threshold and to provide a reference for the further development and use of Moringa as animal feed. 40 Sprague Dawley rats were selected and given transoral gavage for 28 consecutive days.The T1,T2 and T3 groups were observed for general behavior, body weight, and food intake. Blood and serum biochemical indices were quantified, and histopathology was performed to evaluate the effect and safety of Moringa.The results of the toxicological test showed that (1)Only T1 groups experienced diarrhea. (2) The body weight and food intake of rats in each group were normal compared with the control group. (3) The hematological and serum biochemical indices of rats in the T1 group were significantly different from those of CK but were in the normal range; (4) The results of microscopic examination of the heart, liver, spleen, lung, and kidney of rats in each group were normal, but inflammation occurred in stomach and jejunum of rats in the T1 group, but not in the ileum. The gastrointestinal tract of rats in the T2 and T3 groups were normal. (5) No abnormal death occurred in any of the treatment groups.The results of this study revealed that gavage of Moringa homogenate at a dose of 6g/kg · BW can cause diarrhea in rats. Although there is no pathological effect on weight, food intake, blood and serum biochemical indicators in rats, there are pathological textures in the gastrointestinal tissue caused by diarrhea. Therefore, the safety threshold of Moringa homogenate should be ≤ 3g/kg · BW.
The effects of green finance on enterprises’ green innovation under the "dual carbon" goal: an exploratory study based on fsQCA
Authors: Lou Sha , Yao Chunqiong , Zhang Dehua 
Published: September 2023

Abstract
The increasingly severe environmental pollution problem has forced decision-makers to incorporate green innovation into the agenda of high-quality economic development. The topic of green finance has caught the attention of policy makers and industries. However, the impact of green finance on corporate green innovation is still unexplored. We use China’s data from 31 provinces (333 cities) in 2021 to examine the link between corporate green innovation and green finance. This paper analyzes the mixed effect of green finance on green innovation of enterprises by using the qualitative comparative analysis method of fuzzy set. The factors include green credit, green bond, green investment, green insurance and green subsidy. Our results manifest that green innovation in businesses is not a product of a single antecedent situation, but rather the interaction of several antecedent conditions. Green insurance and green subsidy are the core prerequisites for high green innovation in enterprises, and green credit plays an auxiliary role. When there is a lack of green insurance, green bond and green subsidy play a key role, leading to a high level in green innovation of businesses. In addition, the impact of various antecedents on the level of green innovation performance in enterprises is asymmetric. Policy makers should attach importance to providing financial support to firms and minimize the risks of green innovation by expanding financing channels. Our findings enrich the literature on green innovation and finance, and provide beneficial practical insights for green innovation in enterprises.
Tibial tuberosity maturation assessment by ultrasonography and screening for Osgood- Schlatter Disease in children and adolescent athletes: a cross sectional study
Authors: Dinescu Stefan , Stoica Doru , Bita Cristina Elena , Morosanu Aritina , Andreea-Iulia Nicoara , Mihaela Cirstei , Alexandru Cosma Marian , Vreju Florentin 
Published: September 2023

Abstract
Background
The tibial tuberosity maturation process is a developmental period during which insertional injuries can occur, such as Osgood-Schlatter disease. A four-stage classification system is commonly used to assess the developmental features of the tibial apophysis. Previous studies have shown that this maturation process begins earlier in girls which tend to progress 1 to 2 years earlier to the maturity stage than boys. Osgood-Schlatter disease is classified as traction apophysitis caused by excessive sports-related stress and occurs at the anterior aspect of the tibial tuberosity. This study was aimed to analyze the progression of tibial tuberosity maturation in relation to age of children and adolescent athletes. In addition, subjects included in the study were screened clinically and through ultrasound for development of Osgood-Schlatter disease.
Methodology
This was a single center cross-sectional study on 116 children and adolescent subjects with ages between 7 and 18 years. All subjects were practicing at least one sport regularly. All subjects were screened for symptoms related to Osgood-Schlatter disease and examined by ultrasound of the knee in order to establish the maturation stage of the tibial tuberosity based on a 4-point scale.
Results
Tibial tuberosity maturation grade was distributed as follows: grade 1 (n = 31, 26.72%), grade 2 (n = 9, 7.76%), grade 3 (n = 27, 23.28%) and grade 4 (n = 49, 42.24%). On clinical examination, only three cases presented symptoms associated with Osgood-Schlatter disease, which results in a very low prevalence of only 2.6% in the study population. All three cases displayed suggestive features on ultrasound examination. The majority of subjects over the age of 14 showed complete bone maturation. Between the ages of 13 and 15 years, female subjects showed higher proportions of complete bone maturation compared to males.
Conclusion
Our study describes the age pattern of the tibial tuberosity maturation process in children and adolescent athletes. Ultrasound imaging allowed for an accurate differentiation between the four stages of bone maturation and also offered a detailed view of the pathologic features associated with Osgood-Schlatter disease.
Assessing the Feasibility of a Novel Preventive Mobile Health App among Informal Caregivers of Outpatients at Risk of Developing Pressure Ulcers: A Quasi-Experimental Study
Authors: Polychronis Giannis , Noula Maria , Petrou Christos , Roupa Zoe 
Published: September 2023

Abstract
Pressure ulcers (PUs) are a major health concern. In today's tech era, mobile health applications (mHealth apps) offer real-time data, efficient scheduling, and automation, leading to cost-effective care and improved patient satisfaction. This study aimed to assess the feasibility of a novel preventive mobile health application targeted at informal caregivers of outpatients at risk of developing pressure ulcers. In this quasi-experimental study, 23 Informal Caregivers (ICs) were assigned to the intervention group, and 22 to the control group (n = 45). Feasibility was assessed by considering app utility, ease of use, knowledge gaps in prevention, PU rates, and ICs' self-efficacy. Data was collected at baseline, 2 months, and 4 months, and analyzed using descriptive statistics and inferential analysis. Group disparity in improvement: Prevention knowledge (p = 0.040) and patient support efficacy (p = 0.049). Control experienced no shift; Intervention (mHealth app) showed progress. Initial app acceptance was low but grew after 4 months (p = 0.010). After 4 months, perceived usefulness was linked to support efficacy (r = 0.40, p = 0.05), despite steady ease of use perception. This investigation proposes that the innovative preventative mHealth app has the potential to be viable and is well-received among ICs caring for outpatients at risk of developing PUs. In addition, the temporal fluctuations in metrics between the groups suggest that this application could serve as an advantageous instrument in aiding the efforts of ICs in PU prevention.
SUCCEED Africa: Protocol for a multi-method pilot study of a community-based intervention for people with psychosis in West and Southeast Africa
Authors: Greenley Rachel , Tamambang Rita , Koroma Alhaji , Fasoranti Bisola , Munetsi Ephiphania , Chinoko Hilda , Stevens Nancy , Goba Nyaradzo , Kinyabo Philani , Bella-Awusah Tolulope , Ryan Grace K 
Published: September 2023

Abstract

Background: Recent reviews have highlighted the need for participatory research to design and evaluate inclusive, community-based interventions that address the diverse needs of people with lived experience of psychosis, within and beyond the health sector. The SUCCEED Africa consortium aims to co-produce a six-year programme of research following a Theory of Change-driven approach. This protocol describes the pilot study in which SUCCEED’s community-based intervention, research tools and processes will be tested on a small scale in four countries (Malawi, Nigeria, Sierra Leone, Zimbabwe) in preparation for larger-scale evaluation research.
Methods: The pilot uses a before-and-after study design investigating change in subjective quality of life (WHOQOL-BREF) in adults diagnosed with a primary psychotic disorder or another mental disorder with psychotic symptoms who are offered the SUCCEED intervention over a four-month period. Nested within this study are: a baseline assessment of the feasibility, acceptability and face validity of WHOQOL-BREF as a measurement tool and validity of proxy versus self-completion; and a multi-method process evaluation examining key process indicators and implementation, service and client-level outcomes. Methods include: baseline cognitive interviews; semi-structed observation and routine monitoring and evaluation of service delivery; endline interviews and focus group discussions; and a comparison of provider competencies at endline (using an adapted version of the ENACT tool). At each of the four pilot sites, participants will include: ten people with lived experience of psychosis, recruited from either health services or community settings using purposive sampling to maximise variation; up to ten adult family members (one per participant with lived experience) involved in their care; the peer support worker, community support worker and supervisor responsible for the intervention; and the data collector responsible for administering WHOQOL-BREF. Recruitment will take place in July and August 2023.
Discussion: To the best of our knowledge, this will be the first study of a community-based intervention incorporating lay-delivered case management, formal peer support and livelihoods activities for people with lived experience of psychosis in sub-Saharan Africa. Findings will be relevant not only to SUCCEED but also to others interested in promoting rights-based approaches to community mental health in low-resource settings.
Trial Registration: US National Library of Medicine (ClinicalTrials.gov), Protocol reference ID 28346. Initially registered retrospectively July 20/2023: In review.
Characteristics of Absorbing and Non-Absorbing Aerosol over South Africa using MODIS and OMI satellite measurements
Authors: Onyeuwaoma Nnaemeka , Sivakumar Venkataraman 
Published: September 2023

Abstract
A study on the spatiotemporal variation of aerosols over South Africa was conducted using MODIS, OMI, MERRA-2 and CALIPSO data from 2004 to 2023. The study showed that absorbing aerosols dominates the aerosol regime in all the study locations while exhibiting seasonal variations. Further to this, aerosols were apportioned from the different sources in each location using HYSPLIT cluster analysis. During the period under consideration, aerosol loading and AAOD were on the increase in almost all the locations and the peak period was during spring (SON) and summer (DJF). This work also showed that diurnally aerosol loading varies extensively at some locations. Consequently, the Kalahari Desert (KD) and Namibian Desert (ND) are the leading sources of dust aerosols in South Africa, especially locations within the northeast and northwestern parts of the country, while industrial emissions and biomass footprints were also observed. Elevated smoke was also observed around the ports and coastlines which is likely emissions from ships docking at the ports. Finally, the study demonstrated that Durban (DBN), Nelspruit (NPT), Cape Town (CPT) and Polokwane (PLK) are the most polluted sites in South Africa and the major aerosol constituents were identified to be elevated smoke and dust in addition to the contribution from marine for DBN. Hence, more than 37% of the aggregated aerosols loading occurred in Durban (DBN), Nelspruit (NPT), and Cape Town (CPT) where absorbing aerosols loading were very conspicuous. This high concentration of aerosols is attributable to the wind regime prevalent around these locations in addition to the socio-economic activities therein.
Assessment of Heavy Metals Accumulation and Translocation Potential in Some Native Plants Species Collected from Contaminated Soils
Authors: Kanwal Sadia 
Published: September 2023

Abstract

Phytoremediation of heavy metals is considered as an environmental friendly and cost effective technique for cleaning of contaminated soil, especially when native plant species are used. The purpose of the present research was to evaluate the potential of native plant species for accumulation and translocation of selected metals (Cd, Cr, Cu, Ni, Pb, Zn). Twenty one plant species were collected from the ten polluted sites of metropolitan cities (Rawalpindi and Islamabad), Pakistan. Plants tissues (shoots and roots) were analyzed for the accumulation and translocation of heavy metals (Cd, Cr, Cu, Ni, Pb, Zn). Metals accumulation index (MAI) were also evaluated for the selected plants species. Heavy metals concentration was in the order of; Zn > Cu > Ni > Pb > Cr > Cd. Overall, it was observed that R. communis, C. dactylon, C. sativa, P. hysterophorus, P. plebeium, F. Adiantum, C. didymis, R. muricatus and T. officinale had higher metals accumulation and translocation potential. In root part of plants, more concentrations of heavy metals were observed as compared to shoot part of plants. Furthermore, higher MAI was observed in R. communis, P. hysterophorus and P. plebeium. The results indicated that selected native plants species had higher accumulation and translocation potential for heavy metals and can be used for phytoextraction and phytostabilization of metals polluted soils.
TNC+ fibroblasts involve in skin inflammation via neuro-immune and interacting with T cells
Authors: Hu Yibo , Zhao Yuanyuan , Zhang Fan , Zhang Xiaolin , Dai Xixia , Zhang Yushan , Jiang Ling 
Published: September 2023

Abstract
Background
Neuro-immune interactions play a crucial role in the pathogenesis of various skin diseases, TNC + fibroblasts are recently identified as key participants in this process in psoriasis. However, the molecular mechanisms underlying their impacts on different skin diseases remain poorly understood.
Methods
We collected Bulk RNA-Seq/Array data, single cell and spatial RNA-Seq data of more than 20 skin diseases from public databases and processed them using several bioinformatics tools, then identified the key functions, transcription factors, cell trajectory of TNC + fibroblasts, and the interactions between TNC + fibroblasts and immune cells, thus revealed the role and molecular mechanisms about TNC + fibroblasts involving in neuro-immune in skin diseases.
Results
Our analysis found that TNC + fibroblasts and neuro-immune involved in different skin diseases, especially inflammation and tumors. TNC was correlated to inflammatory genes and immune cell infiltration, its over-expression was a crucial feature of inflammatory fibroblasts in skin diseases. TNC + fibroblasts had intensive interactions with different immune cell, especially T cells, mainly through ligand-receptor pairs such as collegens-CD44. We further found that inflammatory and cellular structure-related functions were activated in TNC + fibroblasts, transcription factors EPAS1, HIF1A, and STAT1 could be main intermediates. Besides, the molecular patterns were varied in different diseases.
Conclusions
Our study sheds light on the molecular mechanisms underlying neuro-immune interactions in skin diseases and provides new insights into the role of TNC + fibroblasts in inducing skin abnormalities, especially inflammation.
Bioelectric Device for Effective Biofilm Inflammation Management of Dental Implant
Authors: Lee Jihyun , Kim Young Wook 
Published: September 2023

Abstract
Dental implant inflammation is primarily caused by oral biofilms, which form within 8 hours, particularly at 37°C, thereby requiring diligent cleaning. Considering the complex management of dental implants, a novel technology based on the bioelectric effect (BE) to combat inflammation has emerged. A BE-integrated toothbrush was developed and clinically tested on patients with dental implants (N = 36). Our findings revealed a significant average plaque index reduction of 67% with BE technology compared with that at baseline (P < 0.05), whereas non-BE did not yield statistical significance even after four weeks of use (P > 0.05). The bleeding index demonstrated a 59% average reduction in all surfaces with BE technology (P < 0.05), whereas the non-BE group exhibited no significant change. Substantial reductions in total plaque and bleeding indices suggest that using BE toothbrushes can help effectively remove oral biofilms and treat bleeding symptoms.
Research on identification algorithm of pipeline weld surface defects under complex background based on YOLOv7
Authors: xu xiangqian , li xing 
Published: September 2023

Abstract
Aiming at the problems of low target detection accuracy and high leakage rate of the current traditional weld surface defect detection methods and existing detection models, an improved YOLOv7 pipeline weld surface defect detection model is proposed to improve detection results. In the improved model, a Le-HorBlock module is designed, and it is introduced into the back of fourth CBS module of the backbone network, which preserves the characteristics of high-order information by realizing second-order spatial interaction, thus enhancing the ability of the network to extract features in weld defect images. The coordinate attention (CoordAtt) block is introduced to enhance the representation ability of target features, suppress interference. The CIoU loss function in YOLOv7 network model is replaced by the SIoU, so as to optimize the loss function, reduce the freedom of the loss function, and accelerate convergence. And a new large-scale pipeline weld surface defect dataset containing 2000 images of pipeline welds with weld defects is used in the proposed model. In the experimental comparison, the improved YOLOv7 network model has greatly improved the missed detection rate compared with the original network. The experimental results show that the improved YOLOv7 network model mAP@0.5 can reach 78.9%, which is 16.2% higher than the original model, and the detection effect is better than the original network and other classical target detection networks.
Rosette‑forming glioneuronal tumor in the Posterior Fossa: Case Report and Literature Review
Authors: Zhang Ying , Li YiHua , Wang Xiaoying , Tang Yinda , Zhao Hua , Wang Baimiao , Wang Lifeng , Li Shiting 
Published: September 2023

Abstract
Rosette‑forming glioneuronal tumors (RGNT) is a rare type of glioneuronal neoplasm. We report a case of a typical RGNT in a 15-year-old female presenting with headache and vomiting for one month. Magnetic resonance imaging (MRI) revealed a cerebellar vermis mass that protruded into the fourth ventricle. Histological examination showed a biphasic pattern of rosettes and astrocytic components composed of oligodendrocyte-like cells, with synaptophysin (SYN) and glial fibrillary acidic protein (GFAP) immunopositivity in both patterns. Next-generation sequencing (NGS) identified FGFR1 p.K656E mutation and PIK3CA p.E545A mutation in this patient. Through this case report, we aim to deepen the understanding of RGNT.
Targeted mutagenesis of Medicago truncatula Nodule-specific Cysteine-rich (NCR) genes using the Agrobacterium rhizogenes-mediated CRISPR/Cas9 system
Authors: Güngör Berivan , Biró János Barnabás , Domonkos Ágota , Horváth Beatrix , Kaló Péter 
Published: September 2023

Abstract
The host-produced nodule specific cysteine-rich (NCR) peptides control the terminal differentiation of endosymbiotic rhizobia in the nodules of IRLC legumes. Although the Medicago truncatula genome encodes about 700 NCR peptides, only few of them have been proved to be crucial for nitrogen-fixing symbiosis. In this study, we applied the CRISPR/Cas9 gene editing technology to generate knock-out mutants of NCR genes for which no genetic or functional data were previously available. We have developed a workflow to analyse the mutation and the symbiotic phenotype of individual nodules formed on Agrobacterium rhizogenes-mediated transgenic hairy roots. The selected NCR genes were successfully edited by the CRISPR/Cas9 system and nodules formed on knockout hairy roots showed wild type phenotype indicating that peptides NCR068, NCR089, NCR128 and NCR161 are not essential for symbiosis between M. truncatula Jemalong and Sinorhizobium medicae WSM419. We regenerated stable mutants edited for the NCR068 from hairy roots obtained from A. rhizogenes-mediated transformation. The analysis of the symbiotic phenotype of stable ncr068 mutants showed that peptide NCR068 is not required for symbiosis with S. meliloti strains 2011 and FSM-MA either. Our study reports that gene editing can help to elicit the role of particular NCRs in symbiotic nitrogen fixation.