bluuebunny/crossref_metadata_2025_split huggingface dataset:
El Docente como Líder Inspirador de la Transformación Social
Authors: Taris Toalombo Fabián Vicente , Rea Hinojoza José Manuel , Quinatoa Chimborazo Segundo Gerardo , Hinojosa Manobanda Segundo German 
Published: May 2023

El educador es reflejo de una sociedad en desarrollo de su conciencia cívica; por ello, el ser docente constituye una condición de vida, donde, toda acción acompaña su investidura; estigma, que realza la esencia de la nobleza humana tras concebir la inteligencia como un cimiento, de donde emergen muchas dimensiones y categorías de análisis, que le permite otorgar puntos de vida temporales a todos los que integran su comunidad escolar, promoviendo la necesidad de aprender para la vida, circunscrita en el valor de la identidad personal y realce social; pues, la complexión activa de la praxis, es un sistema relacional. De esta manera, al ejercer funciones gerenciales, es cardinal que el profesional de la docencia en su intento de pedagogizar la direccionalidad del aprendizaje, puede llegar a convertirlo en un sublime proceso de liderazgo, donde prevalezca lo organizacional desde su noción biótica de interacción. Esta vigencia en términos de identidad determina el camino multiexistencial, por cuanto ha de mover voluntades para ir redescubriendo al sujeto, tomando en cuenta su estructura, emociones y estimación en aras de motivar sus niveles de compromiso y responsabilidad encauzados a un liderazgo inspirador orientado hacia la transformación social. En consecuencia, en el presente artículo se pretende describir el rol del docente desde su capacidad de "influir" favorablemente sobre sus estudiantes, siendo fiel ejemplo de inspiración para transformarlos socialmente, lo cual es reflejo de las mejores prácticas profesionales y las experiencias exitosas de sus estudiantes para que con su ejemplo enseñe. En efecto, la importancia del liderazgo le permite al sistema educativo concatenar el profesionalismo, la formación, el trabajo, la entrega personal y la vocación, como dimensiones que acompañan "la inspiración" del buen maestro.
Observation of Vertically Ejected Plumes Generated by the Impact of Hollow Projectiles at Various Velocities
Authors: Kadono Toshihiko , Suzuki Ayako I. , Suetsugu Ryo , Maeda Ryusei , Watanabe Tatsuya , Miyaji Nina , Murayama Ayaka , Yoshida Fumi , Higuchi Arika , Shimaki Yuri , Hasegawa Sunao 
Published: May 2023

Abstract
Recently, impact experiments in space have been conducted in planetary exploration using hollow or internally structured projectiles. In laboratory experiments using hollow projectiles to investigate the differences in crater and ejecta from the case of solid projectiles, a plume perpendicular to the target surface has been observed, which has not been seen in conventional cratering experiments using solid projectiles. In this study, we conducted crater-formation experiments using hollow resin projectiles to understand the mechanism through which vertical plumes form in the case of hollow projectiles. We examined the generation of a vertical plume as a function of the impact velocity, v
imp. We found that (i) no vertical plume occurs at v
imp < 200 m s−1, (ii) the cases with or without a vertical plume are mixed at 200 < v
imp < 350 m s−1, (iii) no vertical plume occurs at 350 < v
imp < 800 m s−1, and (iv) a vertical plume occurs at 2 < v
imp < 3 km s−1. We qualitatively discussed the generation mechanism of the vertical plume using the results of recovered projectiles. Depending on v
imp, an empty hole in which there is no projectile materials can be opened along the central axis, resulting in the generation of a vertical plume.
International PhD students in France under COVID-19 Crisis
Authors: Ballatore Magali , Bertrand Jean-Baptiste 
Published: May 2023

Depuis le début du xxi e siècle, la cartographie de la mobilité des doctorants a changé, elle s’est élargie et diversifiée ; elle s’accompagne de plus en plus de mouvements multicentriques, même si ces mouvements concernent encore majoritairement les Européens et les Américains. Depuis 2020, cependant, la crise sanitaire a rendu cette mobilité plus compliquée. Elle a pu être empêchée ou fortement limitée. Nous avons émis l’hypothèse que les jeunes chercheurs internationaux, peu étudiés malgré la forte internationalisation de la formation doctorale, ont été particulièrement touchés. Cet article propose donc d’étudier les conséquences de la récente crise sanitaire sur l’expérience des doctorants internationaux en France. Il s’appuie sur une enquête récente par questionnaire. L’analyse des données statistiques et le contenu des questions ouvertes montrent que les restrictions de voyage, les procédures d’isolement et la fermeture des frontières ont en quelque sorte modifié la nature de l’expérience doctorale internationale, augmenté les vulnérabilités, et changé les conditions de travail des jeunes chercheurs internationaux en France.
Towards a ‘care-sharing’ model? Multilateral adjustment strategies for post-pandemic students’ mobility in Europe
Authors: Gatti Tiziana , Maciejowska Dorota , Verzichelli Luca 
Published: May 2023

L’article s’appuie sur les résultats de deux enquêtes sur les pratiques des universités du réseau du Groupe Coimbra en réponse à la crise du COVID-19. Nous développons d’abord un cadre théorique et soulevons quelques questions reliant la réaction à court terme face à l’épidémie à la dimension de la coopération à long terme pour protéger et améliorer la mobilité académique entre les universités.Après avoir analysé la variance entre les universités en termes de déclin de la mobilité des étudiants pendant la première vague de la pandémie, l’article évalue la capacité du réseau à prévenir la démotivation et la méfiance, en combinant les avantages des instruments ex ante de protection de la mobilité avec la mise en œuvre d’outils ad hoc de résolution des crises.La dernière section de l’article développe une interprétation basée sur la notion multidimensionnelle et multifonctionnelle de « partage des responsabilités ». Nous soutenons que les actions multilatérales peuvent renforcer une stratégie d’ajustement globale et préventive. Une telle stratégie, large et responsable, concourra à un retour rapide à des taux de mobilité élevés, activant en même temps des pratiques inclusives et innovantes et diffusant les valeurs de durabilité sociale et environnementale au sein de notre communauté d’apprenants.
« Deus est in luce »
Authors: Solignac Charlotte 
Published: May 2023

L’hapax lu chez Bonaventure « Deus est in luce » se révèle avoir une racine scripturaire qui est la première épître de Jean. Cette affirmation a été peu commentée par les Pères et les docteurs de l’Église, et encore moins questionnée et résolue de façon systématique. Nous proposons de rappeler les principales mentions patristiques et médiévales de l’idée d’un Dieu inhérent à la lumière afin de montrer que sa signification est souvent superficielle et disparate. En effet, cette espèce de « photothéisme », « Dieu est dans la lumière », est-elle une affirmation de nature panthéistique ? Comment concilier une telle affirmation avec le refus chrétien du panthéisme ? Les arguments médiévaux réfutant le panthéisme étant insuffisants pour établir le sens valide de l’affirmation johannique, il faut élucider cet hapax par les développements sur l’ubiquité divine et l’inhérence de Dieu dans les choses, à savoir son être in re , pour tenter d’en déceler quelques sens valides.
Dermatological Manifestations in the Elderly: A Descriptive Cross-Sectional Study
Authors: Aithal Vijay , Chacko Ancy , Prathibha JP 
Published: May 2023

Background:
Aging is mainly due to chronic interaction between extrinsic and intrinsic factors. The elderly population is highly vulnerable to skin diseases due to immunosenescence, polypharmacy, chronic exposure to ultraviolet radiation, and inadequate nutrition.

Objectives:
(1) To estimate the prevalence of dermatological manifestation in the elderly population. (2) Clinico-pathological correlation of the cutaneous tumors seen in the study population.

Materials and Methods:
A total of 300 elderly patients (above 60 years) who attended the outpatient department and inpatients of a tertiary care hospital, were recruited for the study, during a 1 year period (2019–2020). Patient demographics, brief history, and clinical examination were done. Relevant laboratory investigations, including side laboratory procedures and skin biopsy were done when necessary.

Results:
Most of the patients were between 65 and 70 years, 175 were male and 125 were female. Type-2 diabetes mellitus and hypertension had equal incidence. Dermatophyte infection was the most common presentation, followed by eczema, papulosquamous, and auto-immune bullous disorders. Nail changes were observed in 50% of the patients. Among those who had drug reactions, 50% had drug hypersensitivity syndrome to anti-tubercular drugs. Malignancies, including basal cell carcinoma, were not uncommon. Alcohol, sunlight, and the male gender were associated with an increased risk of wrinkling.

Conclusion:
Health education programs regarding skin disorders and preventive measures in the geriatric population will help improve their quality of life.
A Study of Vitamin D Receptor Gene Polymorphisms and Serum 25-Hydroxyvitamin D Levels in Vitiligo Patients and Controls
Authors: Noronha Tonita M , Girisha Banavasi Shanmukha , Kumari Suchetha , Shetty Shilpa S , Sampath Muthtamil 
Published: May 2023

Background:
Vitiligo is a common pigmentary disorder affecting 0.1%–2% of the global population. Recently, interest has evoked in the role of Vitamin D in decreasing the risk of several chronic diseases. Little is known about the genetics of vitiligo. This study was conducted to investigate whether Vitamin D receptor (VDR) polymorphisms could be the susceptibility markers for vitiligo.

Objectives:
(i) To evaluate the potential association between VDR polymorphisms and vitiligo susceptibility and (ii) To estimate the serum levels of 25–hydroxyvitamin D in case and control groups.

Materials and Methods:
This study included 34 participants (17 with vitiligo and 17 age-and gender-matched healthy controls). After a written informed consent, a detailed history and examination was done. Serum 25(OH)D levels were measured using the enzyme-linked immunosorbent assay kit. Genomic DNA was extracted from the peripheral blood. The VDR polymorphisms were genotyped using the polymerase chain reaction-restriction fragment length polymorphism method. Fok1, Bsm1, Apa1, and Taq1 restriction enzymes were used to determine the genotypes of the respective polymorphisms.

Results:
Nonsegmental vitiligo was the most common type of vitiligo seen in 14 (82.4%) cases. The mean serum Vitamin D level in cases was 35.64 ± 15.68 ng/ml and in controls was 37.00 ± 16.45 (P = 0.81). There was no significant difference in the distribution of VDR polymorphisms between the case and control groups.

Conclusion:
In our study, no significant difference was observed in the distribution of Fok1, Bsm1, Apa1, and Taq1 VDR polymorphisms between the case and control groups. However, we observed a significant association between the Fok1 polymorphism and serum 25(OH) Vitamin D levels in vitiligo patients studied.
A Study of Platelet-Rich Plasma in the Management of Chronic Nonhealing Ulcers
Authors: Rao Angoori Gnaneshwar , Fathima Kousar 
Published: May 2023

Background:
Chronic nonhealing ulcers run protracted course and require prolonged rest and complete avoidance of pressure, antibiotics, and antiseptic dressing, which at times may not yield satisfactory results. Local application of certain growth factors is known to promote healing in these cases.

Objectives:
To study the efficacy of autologous platelet-rich plasma in the management of chronic nonhealing ulcers.

Materials and Methods:
Z-statistics and Chi-square tests were used in the statistical analysis of this study. The study consisted of 30 patients of chronic nonhealing ulcers who presented to the dermatology department. Patients aged between 18 and 65 years of both sexes presenting with noninfective ulcer of duration of more than 6 weeks, treated or untreated and who have normal complete blood picture, were recruited. Diabetic patients with uncontrolled sugar levels were excluded. Ulcer examination was carried out as per clock-face method. Examination of peripheral pulses, nerves, and sensations was carried out. Routine hematological and biochemical investigations were done. Platelet-rich plasma was prepared from patient's blood, and 1.5–2 ml was injected at the healing margins using insulin syringe (26 G) after cleaning. Procedure was repeated once weekly for 6 weeks, and the ulcer healing was assessed.

Results:
Of the 30 cases, 21 (70%) were male and 9 (30%) were female, with a male-to-female ratio of 2.3:1. A maximum number of cases were in the fifth decade (33.3%). Trophic ulcers (TUs) due to leprosy contributed to 30 (88.23%), venous ulcers (VUs) 2 (5.88%), and diabetic ulcers 2 (5.88%). Improvement in area of TUs due to leprosy was 92.5%, in VUs 88.45%, and in diabetic ulcer 98.02% at the end of 6 weeks of platelet-rich plasma therapy.

Conclusion:
Platelet-rich plasma is an easily obtainable blood derivative and is a safe and potentially reasonable adjunct in the treatment of chronic nonhealing ulcers with advantage of no concern of immune reactions or cross-reactions or toxicity. It not only promotes healing but also prevents amputation necessitated by complications due to chronic ulcers.
Impact of COVID-19 on Dermatology Practice
Authors: Janagond Ajit B , Ratan Vartika R , Potthuri Indira , Pandit Vishalakshi S , Inamadar Arun C 
Published: May 2023

Background:
The sudden outbreak of novel coronavirus has caused confusion, anxiety, and fear not only among the general public but also the health-care system. Considering widespread effects of the disease spilling into all aspects of life in general population and health-care workers alike, we conducted a study regarding the impact of coronavirus disease 2019 (COVID-19) on the functioning of the department of dermatology at a tertiary care hospital during the period of lockdown.

Objective:
We aimed to study the impact of COVID-19 infection and lockdown due to pandemic on practice of dermatology and workings in the outpatient department (OPD) at a tertiary care center.

Materials and Methods:
A cross-sectional, observational study was conducted on patients attending the dermatology OPD at a tertiary care center from April 11, 2020, to May 31, 2020. Patients were interviewed on the basis of a simple questionnaire seeking demographic details, complaints, diagnosis, history, and duration of treatment. Data obtained were recorded as numbers and percentages.

Results:
A total of 1022 individuals participated in the study with 620 (60.6%) males and 402 (39.33%) females. Among them, 625 (61.15%) were localities and 395 (38.64%) were from surrounding rural areas. The age of patients ranged from 6 months to 94 years, and majority were farmers. Eight hundred and twenty-nine (81.1%) were educated and 146 (14.2%) were illiterates. Six hundred and ninety-seven (68.1%) of the participants were new and 325 (31.8%) follow-up cases. Dermatophytosis 194 (27.8%) and psoriasis 15 (4.6%) were the most common diagnoses among new and old cases, respectively.

Conclusion:
A significant reduction was observed in the number of patients visiting the department seeking treatment. The pandemic necessitated various modifications in the patient examination and management protocols.
Immunohistochemical Demonstration of Interleukin-17 Positivity in Skin Biopsy Specimens of Patients with Chronic Plaque Psoriasis and its Correlation with Severity of Psoriasis and Associated Metabolic Syndrome and Cardiovascular Changes
Authors: Suparna Madivalara Yallappa , Shanmugam Reddy Praveen Kumar , Sumathy Tharayil Kunneth , Mysorekar Vijaya V 
Published: May 2023

Background:
Psoriasis is a chronic inflammatory disease which can be associated with metabolic syndrome and cardiovascular abnormalities.

Objectives:
The aim and objective of the study are to demonstrate interleukin-17 (IL-7) positivity in histopathological sections of psoriatic plaques and to correlate with metabolic syndrome and cardiovascular changes.

Materials and Methods:
Forty-seven patients with chronic plaque psoriasis with body surface area >10% and psoriasis area and severity index (PASI) score >12, in whom skin biopsy showed munro's microabscesses, were evaluated for IL-17 positivity (intensity and proportion) with associated metabolic syndrome according to the National Cholesterol Education Program adult treatment panel III criteria and cardiovascular comorbidities. A co-relation with PASI score was made. IL-17 intensity and proportion were graded with a score ranging from 0 to 3. IBM SPSS version 16.0 was used for statistical analysis and independent t-test and Chi-square test were used for proportion.

Results:
The mean age of patients was 43 years. A total of 15 (31.9%) female and 32 (68.1%) male patients were enrolled. The mean PASI score was 21.6. Metabolic syndrome was seen in 31 (65.96%) patients. There was statistically significant association with raised diastolic blood pressure in patients with metabolic syndrome (P = 0.042). The total number of patients with IL-17 positivity with metabolic syndrome was 21 (63.6%). Of these, 9 (42.9%) cases showed IL-17 positivity in the munro's microabscess, 14 (66.7%) cases in the rest of the epidermis, and 18 (85.7%) cases in the dermis.

Conclusion:
In our study, there was no significant difference in IL-7 positivity between patients with or without metabolic syndrome. Further studies need to be done with large sample size to confirm the significance.
Comparative Clinical Assessment of Updosing of Bilastine and Combination of Levocetirizine and Hydroxyzine in Chronic Spontaneous Urticaria
Authors: Shah Bela , Mistry Deval , Jangid Neha , Shah Shikha , Kamat Shruti , Dhoot Dhiraj , Deshmukh Gaurav 
Published: May 2023

Background:
Second-generation antihistamines (SGAHs) are first-line drugs in management of chronic spontaneous urticaria (CSU). However, almost 50% of the patients do not respond to standard dose of SGAH. Various guidelines recommend either updosing of SGAH or combination of different antihistamines in such patients. However, the studies comparing these treatment regimens are limited.

Materials and Methods:
In this comparative study, CSU patients were randomized to receive standard dose of either bilastine or levocetirizine for 2 weeks. After 2 weeks of treatment, nonresponders received a double dose of bilastine while hydroxyzine 25 mg once daily was added in the levocetirizine group. Patients were primarily evaluated for improvement in CSU, quality of life (QOL), and somnolence.

Results:
At the end of 2 weeks, 23/39 and 17/36 achieved well-controlled urticaria, and at the end of 4 weeks, 9/16 and 5/19 patients achieved well-controlled urticaria in the bilastine and levocetirizine groups, respectively. Only one patient in the bilastine group was symptom free and none in levocetirizine at the end of 4 weeks. At week 2, there was no statistical difference in Urticaria Activity Score over 7 days (UAS7) improvement between both the groups, however, at week 4, there was a statistical difference (P < 0.05). Somnolence was significantly lower in the bilastine group (P < 0.05). Bilastine was statistically significant (P < 0.05) in the improvement of QOL by CU-Q2oL as compared to levocetirizine. No major adverse events were reported during study period, however, bilastine was associated with significantly lower Adverse events (AEs) compared to levocetirizine (P < 0.05).

Conclusion:
Updosing of bilastine improves CSU symptoms without compromising safety as compared to combination of levocetirizine and hydroxyzine.
Comparison of In-Person Versus Teledermatology Consultation in the Development of a New Score: Analysis of Tinea Corporis Score from Baseline up to Two Follow-Up Visits
Authors: Andrea Rosario , Samiksha Shankar Shetty , Ashwini Padubidri Kombettu , Chethana Santhebachalli Gurumurthy , Kanthraj Garehatty Rudrappa 
Published: May 2023

Background:
Conventionally, dermatophytoses demand at least 6 weeks of treatment. However, frequent follow-up can be a burden for elderly, working population, and COVID-19 pandemic. Teledermatology consultation may reduce follow-up visits.

Objective:
To propose a new score that provides a periodic clinical audit and minimizes in-person follow-up visits for patient convenience.

Materials and Methods:
A comparative study between teledermatology and in-person (face-to-face) consultation was conducted in the outpatient department of dermatology JSS Hospital, Mysuru, India from December 2018 to July 2019. The tinea corporis (TC) score constitutes three components: (a) area involvement, (b) erythema intensity, and (c) border visibility. Area involvement by teledermatology consultation was calculated by point counting method of Bahmer. TC score is calculated as the product of area involved and the sum of the erythema intensity and border visibility. These patients were followed up on a weekly basis for a month and values of the proposed score derived from the two methods of consultation were compared. Statistical data collected were tabulated and assessed by the SPSS software version 20 (IBM Corporation, Chicago, USA).

Results:
There were 150 TC cases. Analysis of 77 patients who completed the first follow-up visit by in-person and teledermatology consultation showed that the tinea corporis score (TCS) decreased from 171.25, 157.94 from baseline to 97.4, 98.61, respectively (P = 0.001). Analysis of 30 patients who completed the second follow-up visits showed a reduction in TCS from 138.2, 152.7 to 68.2, 71.7, respectively (P = 0.001). The Pearson score obtained by the two methods in each visit (0.990, 0.969, and 0.971) resulted in a positive correlation.

Conclusion:
TC score may be recommended for both in-person and teledermatology consultation. The ease of calculation, objective assessment, and application of TC score in teledermatology consultation are the advantages.
Pharmacovigilance of Severe Cutaneous Adverse Drug Reactions
Authors: Saini Kriteeka , Sutaria Amita , Shah Bela 
Published: May 2023

Background:
Severe cutaneous adverse drug reactions (SCARs) are idiosyncratic reactions comprising 2% of all drug-induced skin reactions. These include Stevens–Johnson syndrome (SJS), toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms, and acute generalized exanthematous pustulosis. These dermatologic emergencies lead to increased morbidity, mortality, and economic burden and may be a cause of litigation.

Objectives:
The aim was to study the clinicoepidemiological profile of SCARs and establish causal association.

Materials and Methods:
Patients presenting with SCARs over a period of 2 years were included in this observational, cohort, hospital-based study conducted in a tertiary care center in western India. The patterns of drug reactions were analyzed, and the drug causality was established.

Results:
A total of 62 patients were included in this study. SJS was the most common pattern of drug reaction observed. Aromatic anticonvulsants (phenytoin and carbamazepine), antimicrobials (co-trimoxazole and amoxicillin), and nonsteroidal anti-inflammatory drugs were the most common drugs implicated. Drug reactions in people living with HIV/AIDS on antiretroviral therapy were noteworthy.

Conclusion:
SCARs represent the most challenging dermatoses in terms of survival, sequelae, and quality of life. Prompt withdrawal of the offending drug and strict pharmacovigilance can improve the prognosis of SCARs. There is a need for exploration of newer genetic associations which may be the only tool to predict these severe reactions.