bluuebunny/crossref_metadata_2025_split huggingface dataset:
Newborn care in Northern India: A study of regional and seasonal peculiarities for desired professionalism and definitive practices
Authors: Jain Sunil , Samrina Jaskar , Samanta Indranil 
Published: February 2023

ABSTRACT

Introduction:
Improvements in newborn health with study of present status, progressive perfection of practices, and data diligence for future is desirable.

Methods:
Study of mortality and morbidity patterns. Analyze findings for focus areas and for favourable advancements in practices. Corroborate with existing evidence and practice protocols.

Setting:
Tertiary care referral hospital.

Protocols:
Preterm babies given special attention. This includes, in addition to the WHO 10 main recommendations, meticulous monitoring and health education for care. Neonatal jaundice evaluation on the basis of risk factors and clinical monitoring.

Results:
A total of 1749 live, born babies (2018–2020) were studied. The neonatal mortality rate in the study was 6.29. Preterm births were 102 (5.83%), with mortality of 7.84%, that is, 8 out of 102 preterm babies, and overall 4.57 premature deaths per 1000 live births. Prematurity was the commonest cause of mortality, responsible for 8 out of 11 deaths (72.73%). Birth asphyxia incidence was 5.26% (92 babies) with a case fatality ratio of 4.35%. Newborns with severe birth asphyxia were 7, and of these 4 (all premature) had fatal outcome. The low birthweight (LBW) incidence was 13.32% with the majority (79.83%) in the 2000–2499 g range. Preventive practices for hypothermia were 100% successful. An unusual rise in incidence and severity of hyperbilirubinemia during December 2018 to February 2019 when winter was severe was noted.

Conclusion:
Mortality reduction requires focusing on prematurity. Meticulous monitoring and health education for them improves results. The unusual rise in incidence and severity of hyperbilirubinemia in severe winter points towards the need for vigilance. We need to be forewarned and forearmed for frequent extreme weather events.
Prevalence of disrespect and abuse during childbirth and its related factors in women hospitalized in the postpartum ward
Authors: Hosseini Tabar Jila , Shahoie Roonak , Zaheri Farzaneh , Mansori Kamyar , Hashemi Nasab Leila 
Published: February 2023

ABSTRACT

Background:
Disrespect and abuse during health care is an emerging concept without a common and agreed definition that has not been sufficiently studied in Iran. Therefore, this study was conducted to determine the prevalence of disrespect and abuse during childbirth and its related factors in women hospitalized in the postpartum ward.

Materials and Methods:
This descriptive cross-sectional study was performed on postpartum women admitted to Ghods Hospital, Paveh, who met the inclusion criteria from April to September 2021. Data collection tools included a demographic and obstetric characteristic questionnaire and a checklist of disrespect and abuse during childbirth, which were completed immediately before discharge by 276 participants who were selected by available sampling. The delivery provider also completed the demographic characteristic questionnaire. Data were analyzed using SPSS software version 21 and univariate and multivariate linear regression tests. P <0.05 was considered significant.

Results:
The results showed that all participants had experienced at least one type of abusive care, and the most common forms were non-consented care (100%) and neglect/abandonment (92.4%). Among the studied variables, only drug interventions during childbirth had a role in predicting disrespect and abuse during childbirth (P < 0.03).

Conclusion:
Due to the high level of disrespect and abuse during childbirth, it seems necessary to educate staff about respectful maternity care and increase supervision of respect for maternal rights, and plan to reduce midwifery interventions.
Predicting and grading liver injury in the absence of computed tomographic imaging
Authors: Newton Mario Victor , Subramanyam S. G. 
Published: February 2023

ABSTRACT

Background:
Even developed countries lack computed tomography (CT) scan in rural areas. Availability, affordability and accessibility of CT scan play an important role in the management of blunt hepatic trauma.

Materials and Methods:
A descriptive observational study among 56 hepatic blunt trauma patients as Group 1 and 56 non-hepatic blunt trauma patients as Group 2 enrolled retrospectively. Observational analysis of presence of liver trauma, grades of liver injury (I–VI) and clinical course with the liver function tests are done.

Results:
Aspartate transaminase (AST) (P = 0.02) and alanine transaminase (ALT) (P = 0.003) levels were significantly elevated among Group 1. Significantly elevated levels in Group 1 than Group 2 of AST [467.5 (22–5097) vs. 95 (23–1780); P < 0.001] and of ALT [422 (28–1548) vs. 69 (20–727); P < 0.001] noted. Significant elevation of AST and ALT levels, as the AAST (American Association for the Surgery of Trauma) CT grade of liver injury increases, noted (P = 0.001). Using the ROC curve analysis, the optimal cut-off values of AST and ALT were set at ≥467.5 U/L and ≥111.5 U/L, respectively. At this cut-off, AST had sensitivity 50%, specificity 91.7%, PPV 85%, NPV 66%, ALT had sensitivity 85.3%, specificity 86.1%, PPV 85.3% and NPV 86.1% for liver injury.

Conclusion:
ALT is more sensitive for liver injury. AST peak is seen in the immediate period. Combining clinical assessment, transaminase levels and Focused Assessment with Sonography in Trauma improves the sensitivity and specificity. Transaminase levels can vary with ethnicity and local epidemiological diseases; therefore, optimal cut-off levels should be established for local population. This would predict and grade the liver injury, helping in early decision-making and avoid wasting the golden hour in trauma.
Early integration of palliative care in cervical cancer: Experiences from a pilot study
Authors: Dey Treshita , Mukerjee Anindya , Rai Bhavana , Arora Minni , Kumar Divyesh , Srinivasa GY , Ghoshal Sushmita 
Published: February 2023

ABSTRACT

Introduction:
Palliative care (PC) has been classically synonymous with end-of-life care offered to patients with advanced incurable cancers with an aim to improve their quality-of-life (QoL). However, there is growing evidence to suggest that early integration of PC (EIPC) along with cancer-directed management improves patient-reported outcomes. In this study, we aim to evaluate the impact of EIPC on QoL of cervical cancer patients treated with curative intent.

Material and Methods:
Patients with locally advanced cervical cancer (stage IB2 to IIIB) having eastern cooperative oncology group (ECOG) performance score 0–2 were randomized into EIPC arm and standard of care arm of concurrent chemoradiation by a computer-generated table of random numbers. QoL was assessed by functional assessment of cancer therapy – general (FACT-G) questionnaire twice in both arms. The first assessment was done prior to starting treatment and second assessment at three months after treatment completion. The mean scores on physical, mental, emotional, social, and functional well-being subscales of FACT-G scale were calculated in both arms, and Wilcoxon test was used to evaluate differences in QoL scores within and in between the arms. This trial was registered with Clinical Trials Registry of India (CTRI) vide CTRI/2017/05/008704.

Results:
Fifty patients were enrolled in each arm. However, only 42 and 45 patients in EPIC and standard oncological care arm were evaluated in the final analysis. Comparing QoL scores between the two time points in each arm, the mean pre-treatment scores in EIPC arm was significantly higher than post-treatment scores in the domains of physical and emotional well-being, whereas social and functional well-being scores improved significantly after treatment as compared with that as baseline. However, when compared between two arms, the difference of mean scores pre- and post-treatment were almost similar for physical and functional well-being but statistically significant differences were found only in social and emotional well-being scales.

Conclusions:
Our study is a feasibility study done in an attempt to test the validity of EIPC in cervical cancers. The results are inspiring to conduct robust studies in the future to explore this new domain of integration of palliative services in curable cancers.
Prevalence and predictors of use of cupping among patients attending a primary care center in Riyadh, Saudi Arabia
Authors: Al-Qahtani Saleh Ghufun , Alsulami Bandar A. 
Published: February 2023

ABSTRACT

Background:
Cupping is a cultural/religious treatment modality in Saudi Arabia that has been recently regulated by the Ministry of Health. The objective was to determine the prevalence of cupping use, its predictors, and related beliefs among patients attending a primary care center.

Methods:
Observational cross-sectional study was conducted between January and July 2019 among patients attending Alwazarat healthcare center in Riyadh, Saudi Arabia. The data were collected using a self-completed questionnaire.

Results:
A total of 386 patients were included. Approximately 68.3% of the patients were females, and 41.8% were aged between 26 and 35 years. About 34.2% of the patients had cupping therapy before. Cupping use was higher in older age (P < 0.001), males (P = 0.002), and specific occupations (P < 0.001). The most frequent health problems treated were headache (40.5%), lethargy (13.0%), diabetes (10.7%), and hypertension (9.9%). Most (82.4%) of patients believed that the cupping they used was beneficial. Approximately 27.9% of the patients had cupping done in non-specialized centers, and 50% were not sure about infection control practices. Cupping was associated with the following encouraging factors; religious beliefs (79.8%), previous experience with relatives and friends (74.0%), culture and habits (57.8%), information in social media, and multimedia (52.9%). In multivariate logistic regression analysis, only age >35 years and previous experience of relatives and friends were independent predictors of cupping use.

Conclusions:
Cupping is a popular therapeutic modality among patients seeking primary care services in Riyadh, Saudi Arabia. Authorities are required to continue reviewing the standards of cupping clinics to ensure their license and patient safety.
Cardiovascular reactivity to stress in long-term yoga practitioners
Authors: Banerjee Arijita , Kumar Sumit 
Published: February 2023

ABSTRACT

Background:
Bhramari Pranayama yogic breathing is a very simple exercise of voluntary breathing which mitigates stress reactivity through autonomic modulation of heart rate.

Aim:
To study the effects of long-term practice of the yoga breathing exercise on cardiovascular reactivity to head-up tilt (HUT) test.

Methods:
All the participants were subjected to a 10-item yoga questionnaire. Based on Likert scale scoring, 32 subjects (group I) were selected as long-term yogic breathing practitioners, and autonomic function tests using heart rate variability (HRV) and a provocative stress test and HUT test were conducted. Cardiovascular parameters obtained were compared with controls who had never been engaged in any form of yoga (group II).

Results:
A highly significant decrease in values of both high (HF) and low frequency (LF) variables was observed in group II as compared to group I. However, a highly significant rise in LF/HF has been observed in group I compared to group I (P = 0.004), further indicating a greater withdrawal of vagal tone during the HUT test and also during recovery (P = 0.001).

Discussion:
The results and discussion of HRV analysis during provocative tests concluded that autonomic imbalance was present in the subjects who were not exposed to any form of yoga. Thus, it is advisable to practice yoga in any form regularly to mitigate the early onset of autonomic dysfunction.
Psychometric validation of the hindi version of summary of diabetes self-care activities (H-SDSCA) amongst pregnant women with gestational diabetes mellitus, in Lucknow
Authors: Mallicka  , Singh Shivendra K. , Pandey Amita , Manar Manish K. , Srivastava Shalini 
Published: February 2023

ABSTRACT

Objective:
The English version of the Summary of Diabetes Self-Care Activities (SDSCA) measure is the most often used self-reporting instrument assessing diabetes self-management. This study was aimed at translating English SDSCA into the Hindi version and validating and evaluating its psychometric properties.

Methods:
The Hindi version of SDSCA was developed based on the guidelines provided by the World Health Organization (2008) for translation and adaptation of tool. Following steps were adopted: (1) Cultural and linguistic validation, (2) content validity testing, (3) construct validity testing, and (4) internal validity testing. Sixty women diagnosed with GDM were selected for the purpose of this study.

Results:
The tool showed promising and satisfactory results. Of mention are the results related to Cronbach’s alpha (0.82). The exploratory factor analysis showed three factors that fit the data satisfactorily.

Conclusions:
This study provided evidence for the reliability and validity of the Hindi Summary of Diabetes Self-Care Activities instrument, which may be used in the future to assess diabetes self-management activities among the pregnant women diagnosed with gestational diabetes mellitus among Hindi-speaking population.
Risk factors for relapse in pediatric nephrotic syndrome in Ranchi
Authors: Mishra Rajeeva , Kumari Shiromani , Pathak Apeksha , Prasad Kamal Narayan , Malakar Jagrita 
Published: February 2023

ABSTRACT

Introduction:
The nephrotic syndrome (NS) is a common childhood illness characterized by massive proteinuria, hyperlipidemia, and hypoalbuminemia. It is a disease of relapse, and therefore, it is a major problem to manage cases with frequent relapses. Prediction and prevention of risk factors is the key to successful management of childhood NS. An understanding of the risk factors that determine the course is useful in taking decisions regarding therapy and enables counseling.

Materials and Methods:
Sample size of 100 children of age 1-12 years of age with steroid sensitive nephrotic syndrome over duration of 1 year from April 2020 to May 2021.

Results and Conclusion:
Risk factors for relapse were presence of infection during initial attack and first relapse as well as less time interval between remission in first episode of nephrotic syndrome and first relapse.incresed risk was also associated with inadequate treatment duration and less serum albumin level and high cholesterol level.
Performance of Aerosol Boxes for Endotracheal Intubation during the COVID-19 Pandemic with Systematic Review
Authors: Christopher R. Ajay , Lohanathan Aparna , Hazra Darpanarayan , Pal Rathijit , Vegiraju Vaishnavi , Abhilash Kundavaram Paul Prabhakar 
Published: February 2023

Introduction:
In the backdrop of the COVID-19 pandemic, endotracheal intubation using an aerosol box (AB) became the norm in the emergency department (ED) and the intensive care unit. We compared two models of AB with different dimensions to compare and identify a device that helps in reducing viral exposure without compromising successful airway management.

Methods:
We conducted this prospective observational study for 7 months (October 20-April 21) on 143 patients presenting with an acute airway compromise to the ED. All intubations were performed using one of the two models available. The primary outcome was time taken for intubation (TTI).

Results:
The overall median time taken to intubate using any AB was 63 (interquartile range [IQR]: 46.2-87.7) s with an 81.9% first-pass success (FPS) rate. TTI for AB I was 67 (IQR: 53-106) s with a 76.3% FPS rate, while TTI for AB II was 57 (IQR: 44-75) s with an 85.9% FPS rate. TTI was much shorter without the use of an AB (34: IQR: 24-53 s) with a 92% FPS rate. Intubations done by emergency physicians with more than 2 years of experience were faster in both with or without AB when compared to intubations done by physicians with <2 years of experience.

Conclusion:
The use of an AB is associated with a longer TTI when compared to intubations done without an AB. TTI was relatively shorter when more experienced emergency physicians performed intubation. FPS rates were low with intubations done using AB.
PELATIHAN PENGEMASAN PAKET WISATA DENGAN MEMANFAATKAN POTENSI WISATA DI DESA BONGAN, TABANAN, BALI
Authors: Nelsye Lumanauw  
Published: February 2023

Di tengah pandemi Covid-19, kegiatan pendampingan desa wisata Bongan terkait pengemasan paket wisata tetap dilaksanakan oleh Politeknik Internasional Bali kerjasama dengan Kementerian Pariwisata Ekonomi dan Kreatif. Upaya ini dimaksudkan untuk membantu desa dalam pemulihan kegiatan pariwisaa dan mempercepat menjadi desa berdaya. Berdasarkan potensi wisata alam, sejarah, dan kearifan lokal masyarakat, desa wisata Bongan berpeluang untuk dikunjungi oleh wisatawan melalui ketersedian paket wisata yang berkualitas. Namun, belum adanya produk wisata yang dikemas menjadi paket wisata yang menarik mengakibatkan desa wisata Bongan jarang dikunjungi wisatawan dan belum dikenal oleh para pelaku pariwisata tentang keberadaan desa. Pengemasan paket wisata dalam kegiatan Pengabdian Kepada Masyarakat oleh tim PIB menggunakan metode persiapan, pelatihan dan pendampingan. Materi pelatihan mencakup identifikasi potensi wisata desa Bongan, produk wisata desa dan pengemasan paket wisata. Pendampingan desa menghasilkan beragam paket wisata yang terangkum dalam sebuah buku, antara lain paket wisata setengah hari, satu hari dan menginap di homestay.
ProgramaciÃ³n verde en el software
Authors: Barzola Edison 
Published: February 2023

La TecnologÃ­a Verde se describe al uso eficaz de los recursos computacionales empequeÃ±eciendo el daÃ±o ambiental, extendiendo su posibilidad econÃ³mica y afirmando necesidades sociales. Esta de tal manera tan bien se puede definir como un conjunto de mÃ©todos que reducen el impacto informÃ¡tico sobre el medio ambiente, de tal manera que se considere el reciclaje de los tantos componentes utilizados para asÃ­ darle a otras personas la posibilidad de que continÃºen obteniendo el provecho de esta tecnologÃ­a. Esta no sÃ³lo identifica a las principales consumidoras de energÃ­a y fabricantes de desperdicios ambientales, sino que esta le ofrece el desarrollo de productos informÃ¡ticos ecolÃ³gicos y de tal manera promueve el reciclaje computacional. En cuanto al software verde, en 1992, la Agencia de ProtecciÃ³n Ambiental de EE.UU. puso en camino Energy Star, un programa de etiquetado voluntario para originar y registrar la eficacia energÃ©tica en los ordenadores, unidades de vigilancia climÃ¡tica, y otros mÃ©todos tecnolÃ³gicos. En cuanto a Algunas de las tecnologÃ­as catalogadas como verdes debido a que apoyan a la reducciÃ³n en el consumo de energÃ­a o emisiÃ³n de diÃ³xido de carbono son computaciÃ³n en nube, computaciÃ³n grid, virtualizaciÃ³n en centros de datos y teletrabajo. La existencia del software verde depende, claramente, de donde arranca la energÃ­a utilizada en los equipos donde el mismo se desarrolla y usa. Esto se trata de un Ã¡rea en la cual no siempre es fÃ¡cil trabajar, primor dial mente por el impacto de los ordenadores y los servidores en los puntos del medio ambiente para la alimentaciÃ³n de los equipos.
DEVELOPMENT OF THE CRISPR/CAS9 SYSTEM FOR THE GENOME
EDITING OF THE NtPDS GENE OF TOBACCO (NICOTIANA TABACUM)
Authors: Shishlova-Sokolovskaya A. M. , Khmilevskaya E. P. , Urbanovich O. Yu. 
Published: February 2023

The CRISPR/Cas9 system is one of the most powerful tools for the editing of plant genomes. In the presented study, the vector constructs developed on the basis of the CRISPR/Cas9 system were used to edit the Nicotiana tabacum genome. The NtPDS gene encoding the 15-cis-phytoene desaturase enzyme was chosen as the target. A knockout of this gene in plants results in the albinism phenotype and dwarfism. Using the in silico bioinformatics platforms, three vector constructs based on the binary pRGEB31 vector were modeled: pRGEB31 + gRNA4-pds, pRGEB31 + gRNAJp2-pds, and pRGEB31 + gRNADeT186-pds, carrying in its composition the CRISRP/Cas9 system with spacers to different parts of the structural domains of the NtPDS gene. Vector constructs were assembled using molecular cloning techniques. The accuracy and correctness of their assembly was confirmed by Sanger sequencing. Вy means of Agrobacteriummediated transformation of leaf discs, the genetic constructs were introduced into the genome of the N. tabacum cv.
Petit Havana SR1 model object. During the cultivation of tobacco leaf discs, it was possible to initiate callusogenesis and morphogenesis processes using all three constructs, however, the maximum frequency of these processes was observed when using the pRGEB31 + gRNA4-pds construct.
Practical Exploration of Integrating Civics into Professional Courses in Open Education Courses
Authors: Zhang Lili 
Published: February 2023

Open education is a kind of education mode relative to traditional education and closed education, featuring student-oriented, diversified teaching methods, no learning restrictions and a high degree of student autonomy. In order to better implement the fundamental educational goal of establishing moral education in the national open university, curriculum thinking politics has become an inevitable trend of curriculum reform in colleges and universities, and an effective means to improve the overall quality level of contemporary talents, which is like a link between thinking politics courses and non-thinking politics courses, and can promote the thinking politics of professional courses with the characteristics of open education, so as to improve the overall quality level of students and promote their overall development. This paper introduces the role of open education courses as a link between open education courses and non-catholic courses, so as to improve the overall quality of students and promote their overall development. This paper introduces the significance of integrating the open education curriculum into the professional courses, and analyzes the current situation of the open education curriculum and the practical methods of its integration into the professional courses.
Upaya Peningkatan Kinerja Aparatur Dinas Pekerjaan Umum dan Penataan Ruang Kabupaten Gowa
Authors: Akhmad Zaenal , Akhmad Akhmad 
Published: February 2023

Penelitian ini bertujuan untuk mengetahui upaya-upaya yang dilakukan Pemerintah dalam meningkatkan kinerja aparatur Dinas Pekerjaan Umum dan Penataan Ruang Kabupaten Gowa. Tipe penelitian bersifat dekskriptif, dasar penelitian yang dilakukan adalah survey. Penelitian ini akan dilaksanakan di Kabupaten Gowa khususnya pada Dinas Pekerjaan Umum dan Penataan Ruang Kabupaten Gowa. Dalam penelitian digunakan teknik pengumpulan data dengan cara studi kepustakaan (library research) dan studi lapang (observasi, interview, dan kuisioner). Populasi sasaran dalam penelitian ini adalah seluruh Pegawai Negeri Sipil pada Kantor Dinas Tata Ruang Perkotaaan dan Permukiman Kabupaten Gowa. Analisis data dilakukan untuk memperoleh gambaran tentang kondisi setiap variabel secara tunggal dengan tabel frekuensi dan analisis deskriptif. Berdasarkan hasil Penelitian bahwa upaya peningkatan kinerja aparatur Dinas Pekerjaan Umum dan Penataan Ruang Kabupaten Gowa dilakukan melalui pembinaan intensif yang diharapkan memberikan implikasi positif. Adapun proses pembinaan yang yang telah dilakukan yakni; pembinaan karier dan prestasi kerja, peningkatan kemampuan dasar untuk melanjutkan pendidikan formal aparat, pendidikan dan latihan bagi pengembangan aparat, peningkatan motivasi aparat serta upaya pembinaan disiplin aparatur di Dinas Pekerjaan Umum dan Penataan Ruang Kabupaten Gowa.