bluuebunny/crossref_metadata_2025_split huggingface dataset:
Manejo de estado de shock distributivo séptico en el paciente adulto
Authors: Sandoval Casasola Kevin Fernando 
Published: September 2023

PROBLEMA: La sepsis es una de las principales causas de muerte en todo el mundo. En adultos, se estima que afecta a 49 millones de personas anualmente, mata a 11 millones y causa millones de discapacidades. La mortalidad por shock séptico se convierte en un problema de salud que requiere la adopción de medidas específicas encaminadas a la pronta detección y tratamiento oportuno. OBJETIVO: determinar el manejo del estado de shock distributivo séptico en el paciente adulto. MÉTODO: Para el desarrollo del estudio se realizó una revisión precisa de bibliografía actualizada, sustentada en fuentes primarias y secundarias. RESULTADOS: La reanimación con líquidos es crucial para la estabilización de la hipoperfusión tisular inducida por el shock séptico, sin embargo se ha demostrado que sólo el 50% de los pacientes en estado de shock son respondedores a volumen y que incrementar el volumen intravascular con cristaloides puede causar complicaciones en los pacientes no respondedores, tales como; acidosis hiperclorémica, hipernatremia, lesión renal aguda y edema pulmonar. CONCLUSIÓN: Se sugiere administrar líquido cristaloide intravenoso a 30 ml/kg en las primeras 3 horas o bolus de 500 ml, reevaluando el volumen intravascular y perfusión de los tejidos para evitar sobrecarga de líquidos.
effect of adding of sabah snake grass (clinacanthus nutans) on the antioxidant and sensory properties of chocolate
Authors: Abdul Hamid Mansoor , Lim Kai Yen , Yeap Chi Hong , Devi Mazarina , Muhamad Nor Maryana 
Published: September 2023

This research was carried out to identify the effect of drying methods on the antioxidant activity of Sabah snake grass leaves as well as the addition of Sabah snake grass powder on the antioxidant and sensory properties of chocolate. Antioxidant properties of chocolate samples were determined through total phenolic content and DPPH radical scavenging activity tests. The best formulation of chocolate filled with Sabah snake grass was determined based on sensory and antioxidant test. Nutrient content of chocolate was determined through AOAC methods whereas water activity and hardness of chocolate shell were determined using water activity meter and Texture Analyzer. Changes of chocolate during storage was reviewed through the aspect of moisture content, water activity, hardness, melting point, microorganism count and sensory score. Results showed that chocolate F2, chocolate filled with 100g of Sabah snake grass powder was the best formulation with satisfaction by panels and higher antioxidant activity. This sample contain 7.25% moisture, 2.19% ash, 30.61% fat, 5.41% protein, 1.94% crude fibre and 52.61% carbohydrate. The storage sample showed significantly difference (p<0.05) in moisture content, water activity, hardness and melting property after kept for eight weeks but still safe to be consumed.
PENGARUH PIJAT STIMULASI OKSITOSIN TERHADAP INVOLUSIO UTERI PADA IBU NIFAS
Authors: B Suriani , Andi Sinta Ida  , Fitriati Sabur  
Published: September 2023

Meningkatnya angka kematian ibu setelah melahirkan yang disebabkan oleh perdarahan. Salah satu cara untuk mengatasi perdarahan itu dengan cara melakukan pijat oksitosin. Pijatan ini dapat merangsang hormon oksitosin yang menyebabkan kontraksi uterus sehingga proses involusi bisa berjalan normal. Pijat oksitosin adalah suatu tindakan pemijatan tulang belakang mulai dari nervuske 5 - 6 sampai scapula yang akan mempercepat kerja saraf para simpatis untuk menyampaikan perintah ke otak bagian belakang sehingga oksitosin keluar. Sehingga dapat mempercepat penyembuhan luka bekas implantasi plasenta, mencegah perdarahan, serta memperbanyak produksi ASI. Tujuan penelitian ini untuk mengidentifikasi pengaruh pijat oksitosin pada ibu post partum yang dipijat oksitosin dan yang tidak dipijat oksitosin. Metode penelitian yang digunakan dalam penelitian ini adalah Quasy eksperiment. Sampel dalam penelitian ini diambil melalui cara purposive sampling. Sampel berjumlah 38 orang yang terdiri dari 18 repsonden kelompok intervensi dan 20 responden pada kelompok kontrol. Instrumen penelitian yang digunakan berupa lembar observasi untuk mengamati penurunan tinggi fundus uterus pada hari pertama post partum. Hasil dari penelitian ini teridentifikasi terdapat pengaruh pijat oksitosin terhadap involusi uterus pada ibu post partum (p=0.026<0.05). Perlunya bidan mensosialisasikan manfaat pijat oksitosin agar ibu nifas dan keluarga mampu melakukan pijat oksitosin.
HUBUNGAN KEBERSIHAN GIGI DAN MULUT (OHI-S) DENGAN GINGIVAL INDEKS PADA WANITA PUBERTAS SMP NEGERI 2 PANCUR BATU
Authors: Rawati Siregar  , Sri Junita Nainggolan  , Aminah Saragih  , Netty Jojor Aritonang  
Published: September 2023

Dental and oral hygiene means a state when the oral cavity include teeth and gum tissue is clean. The actions of cleaning and refreshing the oral cavity, teeth and gums can prevent the transmission of disease through mouth. Dental and oral hygiene (OHI-S) is closely related to the occurrence of gingivitis. The research type used in this study is analytical research with cross sectional method using using Chi-Square Test. The number of the population of this study is 100 people and the sampling technique used purposive sampling, the samples taken are 30 people. The purpose of this study is to find out the relation of dental and oral hygiene (Ohi-S) with gingival index on puberty women. The results showed that the average of debris index were 6 people in good criterion (0,5), moderate criterion 18 people (1,2) and bad criterion 6 people (2,2). The Calculus index defines 6 people (0,4) as good criterion , 15 person (1,4) as moderate criterion and 9 person (2,2) as bad criterion. OHI-S defines the average criteria as follow : 6 people (1,2) as good, 9 people (2,4) as moderate and 16 person (3,6) as bad. Meanwhile, gingival index defines some criteria,1 person (0,9 ) as light, 22 people (1.5) as moderate and 7 people (2,3) as severe. The conclusions of this study is that from the samples, the 30 puberty women, it is found that in average they pay less attention to their oral and dental health. It is expected that the pregnant women should improve their dental and mouth health.
FAKTOR PENYEBAB KEKURANGAN GIZI PADA BALITA (KAJIAN META SINTESIS)
Authors: Ika Puspita Sari  , Siken Agil Wiganata  , Apriliana Dwi Susilowati  , Rian Damariswara  
Published: September 2023

Kekurangan gizi berkaitan erat dengan kurangnya akses sang ibu dalam memberi makanan bergizi pada balita sehingga dapat mengakibatkan gangguan-gangguan pertumbuhan seperti Stunting, Marasmus, Kwashiorkor, dan lain lain. Kajian meta sintesis ini bertujuan untuk membuat sebuah kesimpulan yang tepat terkait dengan faktor penyebab kekurangan gizi pada balita. Pada studi ini peneliti menggunakan jenis penelitian literature review yang bersifat kualitatif dengan berpedoman pada langkah-langkah meta sintesis melalui pendekatan meta-agregasi. Berdasarkan hasil kajian pustaka dari 19 artikel nasional dapat disimpulkan bahwa penyebab malnutrisi atau gizi kurang terdapat dua faktor yaitu faktor penyebab langsung yang meliputi asupan gizi dan jangkitan penyakit infeksi; dan faktor penyebab tidak langsung meliputi pendapatan atau keadaan ekonomi keluarga, pengetahuan ibu, pola asuh orang tua, pendidikan keluarga & masyarakat sekitar, sanitasi, dan fasilitas kesehatan serta jumlah anggota keluarga.
literatur Review : Pengaruh Akupresur terhadap penurunan intensitas nyeri dismenorea
Authors: Rahmawati Alfiah , K Meilia , Adhila Nila 
Published: September 2023

Latar Belakang : Pendarahan menstruasi adalah proses meluruhnya lapisan endometrium yang mengalami penebalan dikarenakan kadar estrogen meningkat selama paruh pertama siklus. Menstruasi yang menyakitkan atau dismenore adalah gangguan ginekologi yang umum di kalangan wanita. Dismenorea didefinisikan sebagai nyeri panggul yang berhubungan langsung dengan menstruasi dan berhubungan dengan berbagai gejala lainnya. Beberapa tindakan pengobatan dapat digunakan yaitu secara non farmakologi dan farmakologi. Terapi Farmakologi dapat dilakukan dengan mengkonsumsi obat-obatan NSAID, paracetamol, asam mefenamat dan pil kontrasepsi oral (OCP). Namun ada resiko terdapat efek samping yang dapat terjadi dari mengkonsumsi obat-obatan. Oleh karena itu dapat dilakukan dengan cara lain yaitu secara non farmakologi seperti melakukan teknik relaksasi nafas dalam, akupuntur, bekam, dan akupresur. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh penggunaan terapi akupresure terhadap penurunan intensitas nyeri dismenorea Metode : Literatur review ini disusun dengan melakukan pencarian dan mengumpulkan artikel penelitian nasional dan internasional menggunakan database Google schoolar, Pubmed, dan Science direct. Penelusuran dilakukan dengan menggunakan kata kunci yang sudah ditentukan dan didapatkan 5 jurnal yang sesuai. Hasil : Dari penelitian ini didapatkan hasil terdapat pengaruh penggunaan terapi akupresure dalam menggurangi nyeri dismenorea
PERBEDAAN KADAR BETA KAROTEN ANTARA DAUN KELOR SEGAR DAN KERING MENGGUNAKAN METODE SPEKTROFOTOMETRI UV-VIS
Authors: Hadiatun Nurul Hadiatun , Hijriani Baiq Isti , Zafrida Siska , Ainutajriani  
Published: September 2023

Moringa leaves are part of the moringa plants that contain nutrients. The chemical compounds contain in moringa leaves are very much, one of them is beta carotene. Beta carotene is a very potential source of vitamin A and has the highest vitamin A activity of all carotenoids. The purpose of this study was to determine beta carotene content in fresh and dry moringa leaves using UV-Vis spectrophotometry method. The population was the moringa leaves, sample was fresh and dry Moringa leaves. Method and analysis of this research was conducted by descriptive method. The results were 19,82?g/g beta carotene of fresh leaves, whereas in dry leaves was 187,45?g/g at 461,1nm wavelength by UV-Vis spectrophotometry. These were caused by various factors, such as; environment, temperature, and humidity. Drying process for dry leaves also affect the beta carotene content of the samples. The conclusion was beta carotene content of dry leaves higher (187.45 ?g/g) than fresh leaves (19.82 ?g/g). Suggestion of this research, it is necessary to measure Moringa oleifera leaves before drying process into oven, make the same sample with different method, or do research with different sample but using the same method
The Phenomenon of Toe Walking in Children, Disease or Habit: A Case Report
Authors: Mahdaniar Sjarfi Chesa Yenni 
Published: September 2023

Background: Some children experience abnormalities in the way they walk, such as toe walking in the form of "bilateral toeing out" or "bilateral tip toe." Bilateral toe walking, also known as “bilateral toeing out,” is a condition in which both of a child's feet tend to move outwards when they walk. On the other hand, “bilateral tip toe” is when a child walks by standing on the tips of the toes without touching heels to the floor. This study aimed to present cases of the toe walking phenomenon in children.
Case presentation: A child checks for complaints on both legs and looks at calcium and vitamin D levels. The patient came with toe walking after the age of 2 years and complained of frequent pain and soreness in both legs for the last 2 weeks. The calcium level in the blood was 5.8 mg/dL, and the vitamin D level was 10 ng/ml. At the request of the patient's parents, X-rays of both extremities were carried out, and the results were within normal limits with no masses or fractures. The patient was diagnosed with bilateral toeing out and bilateral tip toe. The treatment provided by medical rehabilitation specialist doctors to patients is in the form of medical and non-medical therapy.
Conclusion: The patient was diagnosed with bilateral toeing out and bilateral tip toe.
<i>Helicobacter pylori</i> Persistence in Patients with Peptic Ulcer Disease and Chronic Gastritis in the Treatment with Antibiotics and Acid-Suppressive Agents
Authors: Golubkina E. V. 
Published: September 2023

Background. Chronic gastritides still have no division into forms according to the data of the genotyping of Helicobacter pylori isolates. Monitoring the results of anti-Helicobacter pylori therapy cannot be limited to eradication, by taking into account the data on Helicobacter pylori detection in healthy individuals. Is increased acid production associated with the presence of virulent or nonvirulent strains?Objective. To search for the predominance of cagA or any allelic combination of vacA in the isolates from patients with mild and severe chronic gastritis and from those with peptic ulcer disease. To track the time course of changes in the disappearance and repeated gastric colonization with different Helicobacter pylori strains in patients with peptic ulcer disease immediately after anti-Helicobacter pylori therapy and 1.5–2 months later. To confirm or refute the fact that the increased acid production is associated with the presence of virulent Helicobacter pylori strains rather than with the persistence of nonvirulent strains.Methods. The Helicobacter pylori isolates from the gastric biopsy specimens taken from patients with chronic gastritis and peptic ulcer disease were genotyped for cagA and allelic combinations of vacA. The strains from patients who had received anti-Helicobacter pylori therapy were genotyped using the variable number tandem repeat (VNTR) method. Patients with an exacerbation of peptic ulcer disease and those wth an exacerbation of chronic pancreatitis with concomitant gastritis were compared from the level of acid production and from the belonging of Helicobacter pylori to virulent strains.Results. Patients with mild chronic gastritis were observed to have an abundance of nonvirulent allelic combination of vacAs2m2, which differed significantly from its frequency in both the patients with severe chronic gastritis and those with peptic ulcer disease. In the latter patients, the differences between the background bacteriological pattern and the pattern observed after 1.5–2 months had a high degree of significance; in these follow-up periods, in contrast to the control immediately after therapy, the number of eradications increased and the number of cagA-containing strains decreased due to the change of strains. Acid production was significantly higher in the patients with peptic ulcer disease than in those with chronic pancreatits and concomitant gastritis; the former patients show a statistically significant predominance of virulent strains; the latter patients had nonvirulent strains (at the same rate of Helicobacter pylori detection).Conclusion. Filling the blank spots in the study of helicobacteriosis remains relevant due to the progress of genetic methods in bacteriology and to the introduction of novel approaches to assessing the results of anti-Helicobacter pylori therapy.
La Educación y el Trabajo Social un Camino Hacia la Construcción de Ciudadanía
Authors: Guardo Rúa Daniela 
Published: September 2023

La educación es un escenario de múltiples transformaciones sociales y, por tanto, inherente a los conflictos que se generan al interior de la comunidad académica. Es allí interviene el Trabajo Social, generando mecanismos que permitan contribuir a la mejora de esas situaciones. Teniendo en cuenta lo anterior, esta investigación se centra en identificar las principales problemáticas sociales que se presentan dentro y fuera del aula de clase de estudiantes de bachillerato adscritos a instituciones públicas de la ciudad de Cartagena, con la finalidad de establecer estrategias para brindar alternativas a los conflictos sociales. De allí, la importancia de analizar el rol del docente orientador dentro del aula, como un actor que debería promover la construcción de ciudadanía y el desarrollo de una cultura de paz dentro del salón de clases. El carácter de esta investigación es cualitativo, con un diseño de investigación-acción. Para el desarrollo de esta investigación, participaron cinco instituciones educativas del sector oficial, en las cuales se desarrollaron diversos talleres con estudiantes, docentes y directivos. Esta investigación permitió identificar la importancia de ofrecer una educación integral, que además de centrarse en aspectos académicos, se le brinde al estudiante herramientas e insumos para ser un ciudadano que reconozca y cumpla sus derechos y deberes. Asimismo, reconocer el rol del docente orientador en el desarrollo social de los estudiantes y la influencia que estos tienen en la vida de sus alumnos.
The Effect of Fuel Price Fluctuations, Exchange Rates, and Profitability on Stock Returns and Inflation as Intervening Variables
Authors: Satoto Eko Budi 
Published: September 2023

This study aims to analyze the impact of fuel price fluctuations, exchange rates, and profitability on inflation and stock returns. The study employs statistical analysis utilizing SEM techniques and is tested using Smart PLS version 3.0. The study reveals that Fuel price fluctuations have no effect on Inflation. The direction of the relationship between Exchange Rate and Inflation is negative. Profitability has no effect on Inflation. Fuel price fluctuations have no effect on stock returns. Exchange rate has a significant effect with a positive direction on stock returns. Profitability has no direct effect on stock returns. Inflation has a significant effect directly with a negative direction on Stock Returns. Exchange rate has no effect on stock returns through inflation as an intervening variable. Profitability has a significant effect with a positive direction on stock returns through inflation as an intervening variable. The novelty in research is inflation as an intervening variable. Investors are advised that fluctuations in fuel prices and inflation rates need not be a primary concern in their investment decisions. Instead, the focus should be on assessing the potential impact of these factors on company profits. Consequently, investors should emphasize monitoring stock returns periodically while also taking into account variables that could influence a company's stock returns. The study is limited in its scope by examining only three independent variables—Fuel Price Fluctuations, Exchange Rates, and Profitability. Additionally, the research is confined to the period from 2013 to 2017.
Deciphering the Slow-rise Precursor of a Major Coronal Mass Ejection
Authors: Cheng X. , Xing C. , Aulanier G. , Solanki S. K. , Peter H. , Ding M. D. 
Published: September 2023

Abstract
Coronal mass ejections are explosive plasma phenomena prevalently occurring on the Sun and probably on other magnetically active stars. However, how their pre-eruptive configuration evolves toward the main explosion remains elusive. Here, based on comprehensive observations of a long-duration precursor in an event on 2012 March 13, we determine that the heating and slow rise of the pre-eruptive hot magnetic flux rope (MFR) are achieved through a precursor reconnection located above cusp-shaped high-temperature precursor loops. It is observed that the hot MFR threads are built up continually, with their middle initially showing an “M” shape and then being separated from the cusp of precursor loops, causing the slow rise of the entire MFR. The slow rise, in combination with the thermal-dominated hard X-ray source concentrated at the top of the precursor loops, shows that the precursor reconnection is much weaker than the flare reconnection of the main eruption. We also perform a 3D magnetohydrodynamics simulation that reproduces the early evolution of the MFR transiting from the slow to fast rise. It is revealed that the magnetic tension force pertinent to “M”-shaped threads drives the slow rise, which, however, evolves into a magnetic pressure gradient-dominated regime responsible for the rapid acceleration eruption.
Living with a Red Dwarf: The Rotation–Age Relationships of M Dwarfs
Authors: Engle Scott G. , Guinan Edward F. 
Published: September 2023

Abstract
Age is a fundamental stellar property, yet for many stars, it is difficult to reliably determine. For M dwarfs, it has been notoriously so. Due to their lower masses, core hydrogen fusion proceeds at a much slower rate in M dwarfs than it does in more massive stars like the Sun. As a consequence, more customary age determination methods (e.g., isochrones and asteroseismology) are unreliable for M dwarfs. As these methods are unavailable, many have searched for reliable alternatives. The M dwarfs comprise the overwhelming majority of the nearby stellar inventory, which makes the determination of their fundamental parameters even more important. Further, an ever-increasing number of exoplanets are being found to orbit M dwarfs, and recent studies have suggested that they may have a relatively higher number of low-mass planets than other spectral types. Determining the ages of M dwarfs then allows us to better study any hosted exoplanets as well. Fortunately, M dwarfs possess magnetic activity and stellar winds like other cool dwarf stars. This causes them to undergo the spin-down effect (rotating with longer periods) as they age. For this reason, stellar rotation rate has been considered a potentially powerful age determination parameter for over 50 yr. Calibrating reliable age–rotation relationships for M dwarfs has been a lengthy process, but here we present the age–rotation relationships for ∼M0–6.5 dwarfs, determined as part of the Living with a Red Dwarf program. These relationships should prove invaluable for a wide range of stellar astrophysics and exoplanetary science applications.
Ateliers de groupe en diabétologie pédiatrique : quand le patient devient partenaire
Authors: Frippiat J. , Druppel M. , Tenoutasse S. , Messaaoui A. , Hajselova L. , Lambotte I. 
Published: September 2023

L’équipe multidisciplinaire de la clinique de diabétologie de l’HUDERF a mis en place des ateliers de groupe pour les patients atteints de diabète axés sur le partenariat avec le patient. En 2022, 6 ateliers ont effectivement eu lieu, avec un total de 36 participant.e.s d’âges et de genres variés. Outre les thèmes définis des ateliers, divers sujets liés à l’impact du diabète sur la vie quotidienne ont été abordés. Afin d’évaluer la pertinence du projet, nous avons soumis un questionnaire de satisfaction aux sujets. L’appréciation globale a été très positive. Le partage d’expériences avec les autres a été apprécié et a permis de co-construire ensemble des émotions ainsi que d’éprouver un sentiment d’appartenance. Les ateliers ont aussi permis une contenance de l’angoisse des sujets, une (ré)appropriation de la maladie, mais également une augmentation des connaissances théoriques concernant la gestion du diabète. Le modèle proposé engage une redéfinition des rapports entre soignants et soignés en rendant les patients davantage acteurs de leurs soins. En conclusion, ces ateliers ont mis à jour un autre pan de notre clinique, venant compléter notre offre de soins. Nous avons à cœur de poursuivre cette proposition en co-construisant davantage encore le modèle avec les sujets.
Balzac, archéologue du sommeil
Authors: Burston Emma 
Published: September 2023

Dans le contexte d’une époque où circulent beaucoup de discours médicaux et scientifiques qui invitent à discipliner le sommeil considéré comme corrompu, de nombreux personnages dans l’univers fictif de Balzac refusent de, ou peinent à, dormir. Il est possible, en considérant les points de convergence entre ces deux sortes de discours, d’apprendre sur le sommeil au xix e siècle en lisant La Comédie humaine . On y observe qu’une démultiplication d’histoires potentielles, naissant d’un endormissement problématique, met en évidence le potentiel narratif du sommeil – réparateur ou perturbé – dans une œuvre de fiction.