bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh PGPR Akar Kelapa Sawit dan Trichoderma sp. Terhadap Pertumbuhan Bibit Kelapa Sawit (Elaeis guineensis Jacq.) Varietas DXP Simalungun
Authors: Widiyanto Sandi , Wardati Irma , Salim Abdurrahman , Madjid Abdul 
Published: January 2025

Pendahuluan. Tanaman kelapa sawit (Elaeis guineensis Jacq.) berasal dari Nigeria, Afrika Barat. Pembibitan pada budidaya kelapa sawit ada dua tahap, yaitu pembibitan awal (pre nursery) dan pembibitan utama (main nursery). Penelitian bertujuan untuk mengetahui pengaruh aplikasi PGPR akar kelapa sawit dan Trichoderma sp. terhadap pertumbuhan bibit kelapa sawit (elaesis guinnesis jacq.) varietas dxp simalungun di akhir main nursery.
Metode Pengumpulan Data. Penelitian dilaksanakan pada bulan Juni – Agustus 2023 di Laboratorium Lapang Politeknik Negeri Jember. Rancangan percobaan yang digunakan untuk penelitian ini adalah Rancangan Acak Kelompok Non Faktorial terdiri dari 4 perlakuan. Setiap perlakuan terdiri dari 6 ulangan, Adapun perlakuan yang digunakan yaitu perlakuan P0 : tanpa aplikasi PGPR dan Trichoderma sp. P1 : aplikasi PGPR (kerapatan 106 CFU), P2 : aplikasi Trichoderma sp. (kerapatan 109 spora/ml), P3 :aplikasi PGPR (kerapatan 106 CFU) + Trichoderma sp. (kerapatan 109 spora/ml). Parameter yang diamati yaitu tinggi tanaman, diameter batang, jumlah pelepah, volume akar.
Hasil dan Diskusi. Aplikasi PGPR dan Trichoderma sp. berpengaruh sangat nyata terhadap jumlah pelepah 37 MST dan volume akar pada umur 43 MST, berpengaruh nyata terhadap jumlah pelepah 35 MST dan 39 MST, serta berpengaruh tidak nyata terhadap tinggi tanaman dan diameter batang bibit kelapa sawit main nursery.
Simpulan. Aplikasi PGPR dan Trichoderma sp. Berpengaruh tidak nyata terhadap tinggi tanaman dan diameter batang bibit kelapa sawit main nursery.
Pengaruh Pemberian Pupuk Organik Blotong, PGPR (<i>Plant Growth Promoting Rhizobacteria</i>) dan Asam Amino Terhadap Pertumbuhan Tebu (<i>Saccharum officinarum</i> L.) di Kebun Mrawan 1 PG Pradjekan PTPN XI
Authors: Wafiuddin Ahmad Fa'is 
Published: January 2025

Pendahuluan Salah satu masalah yang dihadapi industri gula Indonesia adalah produktivitas tebu yang rendah yang disebabkan oleh Teknik budidaya yang tidak ideal dan Tingkat kesuburan tanah yang rendah. Untuk mengantisipasi hal tersebut maka dilakukan penelitian dengan memanfaatkan kandungan-kandungan nutrisi, mikroba, dan unsur hara yang ada pada pupuk organik blotong, PGPR, dan asam amino dengan cara mengaplikasikan ke tanaman tebu. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh dari pemberian pupuk organik blotong, PGPR (Plant Growth Promoting Rhizobacteria), dan asam amino berpengaruh terhadap pertumbuhan tebu (Saccharum officinarum L.)
Metode Pengumpulan Data. Plot perlakuan yang diamati adalah pertumbuhan tanaman tebu yang ditanam pada lahan dengan dan tanpa pemberian paket mikrobia (pupuk organik blotong, PGPR, asam amino).
Analisa Data. Metode penelitian yang digunakan adalah mengumpulkan data untuk dianalisis menggunakan Uji T untuk kedua perlakuan dengan masing-masing 50 sample.
Hasil dan Diskusi. Hasil Penelitian adalah pemberian pupuk organik blotong, PGPR, dan asam amino berpengaruh sangat nyata terhadap diameter batang (36 MSA) dengan nilai rata-rata 3,34 cm, brix (36 MSA) dengan nilai 19,95%, serta rendemen (36 MSA) yang mencapai nilai 8,41%..
Simpulan. Pemberian pupuk organik blotong, PGPR, dan asam amino berpengaruh terhadap pertumbuhan tebu.
Identifikasi Morfologi dan Kerapatan <i>SporaMetarhizium anisopliae</i> Selama Penyimpanan Pada Suhu Ruang (25ºC)
Authors: Amanda Vita Risti 
Published: January 2025

Pendahuluan. Serangan hama pada tanaman merupakan faktor penghambat bagi peningkatan produksi pertanian di Indonesia. Pengendalian hama menggunakan senyawa kimia dengan dosis yang berlebihan akan menimbulkan dampak yang negatif bagi lingkungan sekitar, maka sebab itu perlu dilakukan pengendalian hama secara terpadu (PHT) salah satunya menggunakan cendawan Metarhizium anisopliae. Keefektifan dari cendawan ditentukan oleh spora dari cendawan itu sendiri. Penelitian ini bertujuan untuk mengetahui morfologi dan kerapatan spora dari cendawan Metarhizium anisopliae..
Metode Pengumpulan Data. Metode yang digunakan yaitu metode deskriptif yaitu dengan cara mengamati morfologi dari cendawan mulai dari warna, bentuk dan kerapatan spora dari cendawan tersebut.
Hasil dan Diskusi. Pengamatan pertumbuhan cendawan M.anisopliae secara makroskopis pada 8 HSI menunjukkan cendawan M. anisopliae mengalami awal pertumbuhan koloni berwarna putih, pada 18 HSI pertumbuhan cendawan yang belum sempurna dikarenakan hanya bagian luar media yang mengalami pertumbuhan secara merata sedangkan pada bagian dalam media koloni dari cendawan masih berwarna putih, pada 28 HSI pertumbuhan cendawan M. anisopliae sudah mengalami pertumbuhan yang sempurna dikarenakan warna koloni dari cendawan M. anisopliae sudah merata keseluruh bagian dari media, pada 38 HSI menunjukkan bahwa cendawan M. anisopliae mengalami perubahan warna pada koloni yang cukup signifikan yaitu hijau kecoklatan bahkan menghitam, pada 48 HSI menunjukkan bahwa cendawan M. anisopliae memiliki warna koloni putih kecoklatan dan menghitam. Pengamatan secara mikroskopis menunjukkan bahwa M. anisopliae memiliki spora yang berbentuk panjang telur hingga silindris dan membentuk rantai, konidia ber sel satu, dengan miselium bersekat, miselium adalah sekumpulan hifa yang membentuk benang benang serta konidiofor berbentuk panjang dan memiliki warna hialin. Kerapatan spora sendiri menunjukkan pada 8 HSI kerapatan spora memiliki nilai 4,20 x 109 spora/ml, pada 18 HSI kerapatan spora menurun menjadi 3,56 x 109 spora/ml, pada 28 HSI cendawan mengalami kenaikan kerapatan spora yang mencapai 4,97 x 109 spora/ml, pada 38 HSI kerapatan spora dari cendawan mengalami penurunan hingga mencapai angka 2,64 x 109 spora/ml dan pada 49 HSI kerapatan spora juga menurun hingga mencapai 1,80 x 109 spora/ml.
Simpulan, Dengan parameter berupa morfologi mikroskopis dan makroskopis dari cendawan serta kerapatan spora menunjukkan bahwa saat pengamatan secara makroskopis cendawan memiliki warna awal koloni putih dan seiring berjalannya waktu cendawan berubah warna menjadi hijau gelap, sedangkan pada saat pengamatan secara mikroskopis cendawan memiliki spora yang berbentuk Panjang telur hingga silindris dan membentuk rantai, konidia ber sel satu, dengan miselium bersekat dan kerapatan spora tertinggi dicapai pada saat cendawan berusia 28 HSI yaitu 49 x 109 spora/ml.
Implementasi SNP 12:2017 pada Perpustakaan SMAN 3, SMAN 13 dan SMAN 16 Kota Pekanbaru
Authors: Supianto Adi , Sudiar Nining , Latiar Hadira 
Published: January 2025

Pendahuluan. Penelitian ini bertujuan untuk mengetahui bagaimana Implementasi Standar Nasional Perpustakaan (SNP 12: 2017) di Perpustakaan SMA Negeri yang ada di Kecamatan Rumbai Kota Pekanbaru, yaitu Perpustakaan SMA Negeri 3 Pekanbaru, Perpustakaan SMA Negeri 13 Pekanbaru, dan Perpustakaan SMA Negeri 16 Pekanbaru.
Metode Pengumpulan Data. Metode penelitian yang digunakan adalah metode deskriptif dengan menyajikan data yang diperoleh berdasarkan obesrvasi di lapangan.
Hasil dan Diskusi. Hasil penelitian menunjukkan bahwa hampir secara keseluruhan ketiga perpustakaan tersebut belum mengimplementasikan Standar Nasional Perpustakaan (SNP 12:2017).
Simpulan. Dari ketiga perpustakaan tersebut perpustakaan SMAN 3 Pekanbaru yang hampir mendekati standar sedangkan dua Perpustakaan SMAN 13 dan SMAN 16 masih jauh dari standar.
Применение метода сквозного счета для моделирования несмешивающихся жидкостей c большим поверхностным натяжением
Authors: Любимова Татьяна Петровна , Иванцов Андрей Олегович , Хлыбов Олег Анатольевич 
Published: January 2025

One of the most important advantages of the level set method is its ability to automatically handle topological changes. Instead of explicitly tracking the interface between the media, the level set method describes them as a zero isosurface of the level set function. This allows numerical modeling of the dynamics of a multiphase fluid as a single medium with varying parameters. It is known that a disadvantage of this approach is the possibility of non-physical oscillations of the velocity field near the interface, which occur at high surface forces due to the error in calculating the curvature of the interface and high gradients of other functions in the transition layer. Another disadvantage of the method is the problem of preserving the masses of liquids during the simulation. In this paper, several modifications of the level set method are described that allow reducing the mass loss of liquids, improving the convergence in the implicit solution of the transport equation, and reducing velocity oscillations near the interface in the case of high values of the surface tension coefficient. The proposed approaches were tested on a standard test problem of the dynamics of two immiscible liquids.
Premenstrual Disorders, Timing of Menopause, and Severity of Vasomotor Symptoms
Authors: Yang Yihui , Valdimarsdóttir Unnur A. , Manson JoAnn E. , Sievert Lynnette Leidy , Harlow Bernard Leslie , Eliassen A. Heather , Bertone-Johnson Elizabeth R. , Lu Donghao 
Published: September 2023

ImportanceAlthough premenstrual disorders (PMDs) end at menopause, it is unclear whether they are associated with the timing and symptom severity of menopause.ObjectiveTo prospectively examine whether women with PMDs have increased risks of early menopause and menopause-related vasomotor symptoms (VMS).Design, Setting, and ParticipantsThis population-based cohort study was nested in the Nurses’ Health Study II (data collected from questionnaire sent between June 1991 and June 2017). Analysis of menopause timing included participants who did not have natural or surgical menopause before study entry, while the analysis of VMS was restricted to women who provided information on VMS. Data were analyzed from August 2022 to March 2023.ExposuresPMDs were identified by self-reported diagnosis and confirmed with symptom questionnaires from 1991 to 2005. Participants were age-matched to women without PMD diagnoses and confirmed absence of or minimal premenstrual symptoms.Main Outcomes and MeasuresDuring follow-up through 2017, timing of natural menopause was assessed biennially, and VMS were assessed in 2009, 2013, and 2017. The association of PMDs with early menopause was assessed by Cox proportional hazards models and with VMS by logistic regression models.ResultsOf 1220 included women with PMDs, the median (IQR) age was 40.7 (37.3-43.8) years; of 2415 included women without PMDs, the median (IQR) age was 41.7 (38.3-44.8) years. The median (IQR) follow-up in this study was 20.3 (17.8-22-2) years. Early natural menopause (menopause before age 45 years) was reported by 17 women with PMDs (7.1 per 1000 person-years) and 12 women without PMDs (2.7 per 1000 person-years; adjusted hazard ratio, 2.67; 95% CI, 1.27-5.59). In addition, 795 women with PMDs (68.3%) and 1313 women without PMDs (55.3%) reported moderate or severe VMS (adjusted odds ratio, 1.68; 95% CI, 1.32-2.14). There was no observed association between PMDs and mild VMS (adjusted odds ratio, 0.99; 95% CI, 0.76-1.28).Conclusions and RelevanceIn this cohort study of US women, PMDs were associated with increased risks of early menopause and moderate or severe VMS. PMDs may be indicative of underlying physiology linked to early menopause and VMS, suggesting a phenotype observable during the reproductive years that may allow clinicians to target women at risk of earlier menopause and subsequent health risks later in the life course.
Relational and physical aggression in preschool‐age children: Associations with teacher, parent, sibling, and peer relationship quality
Authors: Swit Cara S. , Harty Seth C. , Pascoe Shania 
Published: September 2023

AbstractEarly childhood relationships with teachers, parents, siblings, and peers are foundational factors for later social functioning. High rates of childhood aggression have been associated with negative developmental consequences, however, the associations between child aggression on the quality of these formative relationships have not been studied extensively. In a sample of young children attending preschool (N = 114, Mage = 46.27 months, SD = 9.94, 40% girls), this study investigated associations between early childhood relational and physical aggression and the quality of concurrent teacher‐child and parent–child closeness and conflict, sibling relationship quality, and positive peer interactions and peer rejection. Early childhood relational and physical aggression was associated with negative teacher–child relationships, and this was true for boys and girls. Differential patterns of prediction were found for relational and physical aggression on the other relationship variables. Relational aggression strongly predicted more positive peer interactions, whereas physical aggression predicted fewer positive peer interactions and greater peer rejection. Early childhood relational aggression predicted higher levels of teacher‐child closeness, whereas physical aggression predicted lower levels of teacher–child closeness and fewer positive sibling interactions. These findings challenge common perceptions that aggression is negatively associated with relationship quality. Notably, relational aggression relative to physical aggression may be associated with some favorable relationship outcomes. We did not find support for an additive model of aggression whereby children who were both relationally and physically aggressive (co‐morbid) were at higher risk for negative relationship quality. Implications of these findings for future research and prevention and intervention are discussed.
Clinicopathological and circulating cell‐free DNA profile in myositis associated with anti‐mitochondrial antibody
Authors: Wang Yikang , Zhao Yawen , Yu Meng , Wei Luhua , Zhang Wei , Wang Zhaoxia , Yuan Yun 
Published: September 2023

AbstractObjectiveAnti‐mitochondrial antibodies (AMAs) are associated with idiopathic inflammatory myopathies (IIMs). We aimed to summarize the clinicopathological characteristics, assess circulating cell‐free mitochondrial DNA (ccf‐mtDNA), and circulating cell‐free nuclear DNA (ccf‐nDNA) in AMA‐associated IIMs.MethodsMedical records of 37 IIMs patients with AMAs were reviewed. Circulating cell‐free mtDNA and ccf‐nDNA levels in sera from IIMs patients with AMAs (n = 21), disease controls (n = 66) and healthy controls (HCs) (n = 23) were measured and compared. Twenty‐eight immune‐mediated necrotizing myopathy (IMNM) patients, 23 dermatomyositis (DM) patients, and 15 anti‐synthetase syndrome (ASS) patients were enrolled as disease controls. Correlations between variables were analyzed.ResultsLimb weakness was observed in 75.7% and neck weakness in 56.8% of patients. Cardiac involvement occurred in 51.4% of patients. Muscle pathology revealed 81.1% of IMNM, 5.4% polymyositis, and 13.5% nonspecific myositis. Microinfarction was observed in 8.1% of patients. Serum ccf‐mtDNA levels in AMA‐associated IIMs were significantly higher than those in HCs (p < 0.001), but no significant differences between AMA‐associated IIMs and IMNM, DM, or ASS. Serum ccf‐nDNA levels in AMA‐associated IIMs were significantly higher than those in HCs (p = 0.02), and significantly lower than those in DM (p = 0.02). Serum ccf‐nDNA levels correlated negatively with MMT8 total scores (rs = −0.458, p = 0.037) and positively with mRS scores (rs = 0.486, p = 0.025). Serum ccf‐nDNA levels were significantly higher in the non‐remission group (p < 0.01).InterpretationAMA‐associated IIMs exhibit distinct clinicopathological features. Serum ccf‐nDNA may serve as a potential marker for disease severity and prognosis in AMA‐associated IIMs.
Reimagining the Rheumatology Fellowship Interview: Using Participatory Design‐Thinking Process to Create a More Applicant‐Centered Experience
Authors: Kumar Bharat , Feng Alick , Gheriani Gatr‐alnada , Iftekhar Ayesha , Ni Ruoning , Dimachkie Mohamad , Gokalp Gizem , Bazigh Izza , Moy Lindsay , Chao Chen , Lingamaneni Ankitha , Patel Axi , Cepero Gretchen Santana , Iqtidar Tariq , Thoene Patricia Bruffey , Knaack Aaron , Swee Melissa L. , Suneja Manish , Davis Benjamin 
Published: September 2023

ObjectiveDesign thinking is a creative problem‐solving process used to better understand users’ needs and experiences so that a product or service can be improved. Its emphasis on empathy, iterative prototyping, and participatory collaboration make it an ideal methodology for innovation in medical education. We apply this framework to the virtual rheumatology fellowship interview process so that interviews can become more applicant centered.MethodsThis educational quality improvement project uses a design‐thinking framework to identify opportunities and challenges for rheumatology fellowship applicants. The investigators use the 5‐step process (Empathize, Define, Ideate, Prototype, Test) and incorporate rapid qualitative analysis of semistructured interviews to innovate the interview experience. The iterative and collaborative nature of this process has empowered participants to codesign an applicant‐centered interview experience.ResultsInterviews with fellowship applicants (n = 9), fellow physicians (n = 4), and faculty members (n = 3) identified three major dynamics of the interview process: (1) Is it a safe environment to ask questions? (2) How do I exchange information effectively? and (3) How do I fit all these data into the bigger picture? Creative brainstorming techniques at a series of three workshops yielded four prototypes emphasizing customization, hybridization, facilitation, and preparation. A finalized applicant‐centered interview template was devised in preparation for the 2023‐2024 application season.ConclusionDesign thinking has yielded insights into three important dynamics that drive applicant experiences. These insights allow for a redesign of processes so that virtual interviews can be more applicant centered. This framework allows for further iterations and modifications as the needs of applicants and programs evolve over time.
Self‐Adaptive Perception of Object's Deformability with Multiple Deformation Attributes Utilizing Biomimetic Mechanoreceptors
Authors: Lin Waner , Wang Ziya , Xu Yingtian , Hu Zhixian , Zhao Wenyu , Zhu Zhihao , Sun Zhenglong , Wang Guoxing , Peng Zhengchun 
Published: September 2023

AbstractThe perception of object's deformability in unstructured interactions relies on both kinesthetic and cutaneous cues to adapt the uncertainties of an object. However, the existing tactile sensors cannot provide adequate cutaneous cues to self‐adaptively estimate the material softness, especially in non‐standard contact scenarios where the interacting object deviates from the assumption of an elastic half‐infinite body. This paper proposes an innovative design of a tactile sensor that integrates the capabilities of two slow‐adapting mechanoreceptors within a soft medium, allowing self‐decoupled sensing of local pressure and strain at specific locations within the contact interface. By leveraging these localized cutaneous cues, the sensor can accurately and self‐adaptively measure the material softness of an object, accommodating variations in thicknesses and applied forces. Furthermore, when combined with a kinesthetic cue from the robot, the sensor can enhance tactile expression by the synergy of two relevant deformation attributes, including material softness and compliance. It is demonstrated that the biomimetic fusion of tactile information can fully comprehend the deformability of an object, hence facilitating robotic decision‐making and dexterous manipulation.
Force‐Triggered Self‐Destructive Hydrogels
Authors: Rajasooriya Tharindu , Ogasawara Hiroaki , Dong Yixiao , Mancuso Joseph Nicholas , Salaita Khalid 
Published: September 2023

AbstractSelf‐destructive polymers (SDPs) are defined as a class of smart polymers that autonomously degrade upon experiencing an external trigger, such as a chemical cue or optical excitation. Because SDPs release the materials trapped inside the network upon degradation, they have potential applications in drug delivery and analytical sensing. However, no known SDPs that respond to external mechanical forces have been reported, as it is fundamentally challenging to create mechano‐sensitivity in general and especially so for force levels below those required for classical force‐induced bond scission. To address this challenge, the development of force‐triggered SDPs composed of DNA crosslinked hydrogels doped with nucleases is described here. Externally applied piconewton forces selectively expose enzymatic cleavage sites within the DNA crosslinks, resulting in rapid polymer self‐degradation. The synthesis and the chemical and mechanical characterization of DNA crosslinked hydrogels, as well as the kinetics of force‐triggered hydrolysis, are described. As a proof‐of‐concept, force‐triggered and time‐dependent rheological changes in the polymer as well as encapsulated nanoparticle release are demonstrated. Finally, that the kinetics of self‐destruction are shown to be tuned as a function of nuclease concentration, incubation time, and thermodynamic stability of DNA crosslinkers.
Multifunctional PtCuTe Nanosheets with Strong ROS Scavenging and ROS‐Independent Antibacterial Properties Promote Diabetic Wound Healing
Authors: Guo Yaru , Ding Shuai , Shang Changshuai , Zhang Chenguang , Li Menggang , Zhang Qinghua , Gu Lin , Heng Boon Chin , Zhang Shihan , Mei Feng , Huang Ying , Zhang Xuehui , Xu Mingming , Jiang Jiuhui , Guo Shaojun , Deng Xuliang , Chen Lili 
Published: September 2023

AbstractNanozymes, as one of the most efficient reactive oxygen species (ROS)‐scavenging biomaterials, are receiving wide attention in promoting diabetic wound healing. Despite recent attempts at improving the catalytic efficiency of Pt‐based nanozymes (e.g., PtCu, one of the best systems), they still display quite limited ROS scavenging capacity and ROS‐dependent antibacterial effects on bacteria or immunocytes, which leads to uncontrolled and poor diabetic wound healing. Hence, a new class of multifunctional PtCuTe nanosheets with excellent catalytic, ROS‐independent antibacterial, proangiogenic, anti‐inflammatory, and immuno‐modulatory properties for boosting the diabetic wound healing, is reported. The PtCuTe nanosheets show stronger ROS scavenging capacity and better antibacterial effects than PtCu. It is also revealed that the PtCuTe can enhance vascular tube formation, stimulate macrophage polarization toward the M2 phenotype and improve fibroblast mobility, outperforming conventional PtCu. Moreover, PtCuTe promotes crosstalk between different cell types to form a positive feedback loop. Consequently, PtCuTe stimulates a proregenerative environment with relevant cell populations to ensure normal tissue repair. Utilizing a diabetic mouse model, it is demonstrated that PtCuTe significantly facilitated the regeneration of highly vascularized skin, with the percentage of wound closure being over 90% on the 8th day, which is the best among the reported comparable multifunctional biomaterials.