bluuebunny/crossref_metadata_2025_split huggingface dataset:
On‐ and off‐site erosion impacts of restoration measures in a tropical karst watershed
Authors: Fonseca Maria Rita S. , Chaves Henrique M. L. , Uagoda Rogério E. S. 
Published: March 2023

AbstractKarst areas are vulnerable landscapes which, if unprotected, could be permanently degraded. To bridge the gap existing in the reduction of on‐ and off‐site impact of restored tropical karst areas, this study was carried out in a 3.5 ha karst watershed of the Brazilian savanna (Cerrado). Precipitation, surface runoff, and soil loss were measured in representative runoff plots (22.1 × 1.84 m), used to assess the watershed erosion and sediment yield to a downstream sinkhole. The study was carried out during three hydrologic years, between September 2018 and May 2020. The predominant soils in the watershed were Lithic entisol and Quartzsamment, and the original land covers were natural savanna, seasonal forest, and degraded pastureland (Andropogon gayanus). The latter was restored with native savanna species, in the lower part of the watershed, and with a reformed pastureland, in the upper part. The USLE rainfall erosivity (R), soil erodibility (K), and soil cover (C) factors, runoff, soil loss, and the original soil and sediment textures were obtained from the runoff plots. The watershed soil loss and sediment yield were obtained by the USLE and GIS. Precipitation and rainfall erosivity ranged from 936 to 1223 mm, and from 6694 to 7746 MJ mm ha−1 h−1, in the period, respectively. Although the ecological watershed restoration reduced mean soil loss from 11.6 to 5.8 Mg ha−1 year−1, and sediment yield from 29.2 to 14.6 Mg year−1, on‐ and off‐site soil loss tolerances were still exceeded in 29 and 61% of the basin area, respectively. Ecological restoration also reduced the sand and clay content of the sediment entering the underground caves and river downstream, contributing to their hydrologic sustainability.
TVSR‐OR: Tile‐based 360‐degree video streaming over real time streaming protocol with optimized read
Authors: Zeng Qimiao , Yin Zhifan , Pan Qing , Ma Yunxiao , Yu Yuan , Zhuang Yirong , Liang Jie , Yang Shujie , Xiao Han 
Published: March 2023

AbstractAmong video application use cases and scenarios, 360‐degree video applications gradually become significant. The state‐of‐the‐art solution for 360‐degree video streaming is field of view (FOV) transmission, whose quality of experience highly depends on system processing speed and network latency. The extant 360‐degree video FOV transmission profiles transmit multiple video tile streams to the client over either Hypertext Transfer Protocol (HTTP) or Real Time Streaming Protocol (RTSP). The client needs to merge all different tile streams after receiving them, which may cause a data synchronization problem of waiting for each tile to sync in the presents of packet losses. Therefore, we propose a system to select and merge tile streams on the Content Delivery Network (CDN) server and transmit the merged stream to the client. During the streaming service, the client can send a viewport switch request through RTSP signaling, and the server will subsequently deliver the merged video stream of the new viewport to the client after receiving the request. Also, to reduce disk overhead from parallel reads, we optimize the system with a file prefetch strategy to reduce unorganized, random, and parallel reads into serialized reads of large data trunks. We evaluate its performance through user request simulation experiments. Compared with the extant transmission solution, our system provides slightly lower video transmission latency, lower central processing unit (CPU) usage, and better disk performance under heavy service load.
Incorporation of fresh leaves of wormwood (Artemisia herba alba) and/or rosemary (Rosmarinus officinalis) in the diet of rams: Effect on testicular function, sexual behavior, and blood parameters
Authors: Khnissi Samia , Bomboi Giovanni , Khémiri Ikram , Salem Imen Ben , Dattena Maria , Sai Salma , Mustapha Souha Ben , Cabiddu Andrea , Lassoued Narjess 
Published: March 2023

AbstractThis study aimed to investigate the effect of wormwood and rosemary supplementation on some reproductive traits of Barbarine rams. The experiment lasted 2 months. Twenty‐four adult rams were divided into four groups (n = 6) balanced for the weight (53.3 ± 1.2 kg body weight [BW] ± SD). All rams received 1200 g of straw and 600 g of barley. Control rams (C) without aromatic medicinal plant (AMP), while experimental rams received 20 g of fresh rosemary leaves (R), 20 g of fresh wormwood leaves (A), and 10 g of fresh rosemary leaves plus 10 g of fresh wormwood leaves (RA). The results revealed that the live weight of all rams increased (p < .05) in the RA group compared to the C, A, and R groups. Scrotal circumference increased in the R rams when compared to the controls rams (p < .05). For sperm parameters we showed that the A rams had higher sperm concentrations (p < .05). But, the sperm volume decreased in the R rams (p > .05). However, when the rams received rosemary plus wormwood, their sperm volume increased (p > .05). The sperm mass motility was higher for the A, R and AR rams in comparison to the C rams (p = .05). On the other hand, biochemical analysis of the seminal fluid showed no effect of diets on calcium and total proteins concentration. But the measurement of glucose and seminal insulin showed a decrease (p < .05) in these two biochemical markers in group A rams and a decrease (p < .05) in insulin without modification of the glucose concentration in R rams. Blood glucose and insulin decreased in the animals on AMP diet compared to the other groups (p < .05) while aspartate aminotransferase (AST) increased (p < .05). Rosemary leaves (R and RA groups) increased (p < .05) plasma cortisol compared to the other groups. It can be concluded that the addition ofRosmarinus officinalisand/orArtemisia herba albain ram diet can have a positive effect on the reproductive function by increasing the concentration and motility of sperm, plasma testosterone, and sexual behavior.
Response to induction chemotherapy in sinonasal malignancies: A single‐institutional experience
Authors: Nyirjesy Sarah C. , Fenberg Rachel , Heller Margaret A. , Judd Ryan T. , Li Michael M. , Koch Brandon , Bonomi Marcelo , Carrau Ricardo L. , VanKoevering Kyle K. 
Published: March 2023

AbstractBackgroundSinonasal malignancy (SNM) is a heterogeneous group of diseases for which induction chemotherapy (IC) may reduce tumor burden. The purpose of this study was to characterize the response to IC in SNM as a prognostic factor through its effect on survival.MethodsRetrospective cohort of patients undergoing IC for SNM between 2010 and 2019 at our quaternary referral center.ResultsForty‐two patients with advanced SNM were included in the analysis. Patients with a favorable response to IC had higher survival rates than those who had an unfavorable response (5‐year OS: 66.8% vs. 9.7%; p < 0.001; PFS: 56.8% vs. 0%; p < 0.001).ConclusionsResponse to IC in our patient cohort was a prognostic indicator of overall response to treatment. Further elucidation of predictors of response is needed for appropriate patient selection.
Reap while you sleep: Consolidation of memories differs by how they were sown
Authors: Antony James W. , Schechtman Eitan 
Published: March 2023

AbstractNewly formed memories are spontaneously reactivated during sleep, leading to their strengthening. This reactivation process can be manipulated by reinstating learning‐related stimuli during sleep, a technique termed targeted memory reactivation. Numerous studies have found that delivering cues during sleep improves memory for simple associations, in which one cue reactivates one tested memory. However, real‐life memories often live in rich, complex networks of associations. In this review, we will examine recent forays into investigating how targeted sleep reactivation affects memories within complex paradigms, in which one cue can reactivate multiple tested memories. A common theme across studies is that reactivation consequences do not merely depend on whether memories reside in complex arrangements, but on how memories interact with one another during acquisition. We therefore emphasize how intricate study design details that alter the nature of learning and/or participant intentions impact the outcomes of sleep reactivation. In some cases, complex networks of memories interact harmoniously to bring about mutual memory benefits; in other cases, memories interact antagonistically and produce selective impairments in retrieval. Ultimately, although this burgeoning area of research has yet to be systematically explored, results suggest that the fate of reactivated stimuli within complex arrangements depends on how they were learned.
Classroom ethnic diversity, teacher support, and peer victimization: Evidence from four European countries
Authors: Spiegler Olivia , Zingora Tibor , Jugert Philipp 
Published: March 2023

AbstractWe investigated how classroom ethnic diversity is associated with peer victimization, effects of ethnic minority/majority status, and if individual teacher support can buffer potentially negative effects of ethnic diversity. Using two theoretical perspectives (balance of power, ethnic competition), we hypothesized that (1) victimization is more prevalent at intermediate ethnic diversity and less prevalent at lower and higher ethnic diversity, (2) this curvilinear link is stronger for ethnic majority than minority students, and (3) peer victimization at intermediate levels of ethnic diversity is lower when teacher support is high. We conducted multilevel analyses based on the first wave of the Children of Immigrants Longitudinal Survey in Four European Countries (CILS4EU). The analytical sample included 17,882 students, nested in 882 classrooms. Although our hypotheses received no support, the findings showed that diversity was linked to less victimization for ethnic minority student. Teacher support was linked to less victimization for ethnic minority students at every level of classroom diversity but especially when diversity was low and to less victimization for ethnic majority students in classrooms with intermediate to high ethnic diversity. We discuss our findings in light the theoretical approaches and underscore the role of teachers as a protective resource.
Income distribution, financial liberalisations and banking stability: Theory and international evidence
Authors: Wang Shengquan , Luo Rong 
Published: March 2023

AbstractMotivated by Rajan's study and existing economic reform theories (especially the lobby theory), we highlight income inequality as a driver of financial liberalisations. However, no evidence yet supports this idea. To verify this liberalisation‐induced‐by‐inequality hypothesis, the nexus of income inequality and financial liberalisations is formalised and empirically investigated in this paper. We utilise an ordered logit model with two‐way fixed effects and panel data from 91 countries to conduct the analyses. The baseline empirical results indicate that income inequality is a positive and significant determinant of financial liberalisations in aggregate and three component indicators. The results for three component indicators remain stable after a series of robustness checks, including mitigating the potential endogeneity via IV‐2SLS, Lewbel instrumental variable technique and difference within group, assessing the bias from the unobservable variables, considering the persistent and learning effects of liberalisations and the interaction effects, alternating the measures of income inequality, reducing business cycle, and using financial reforms rather financial liberalisation as independent variable. The results for aggregate liberalisations are slightly unstable in models with persistent and learning effects. Thus, liberalisation‐induced‐by‐inequality hypothesis is generally confirmed. In addition, the impacts of income inequality on financial liberalisations are widely heterogeneous across countries, the rate of change in income inequality and wealth inequality could also predict the occurrence of financial liberalisations, and the evidence that income inequality makes the poor easier access credits (i.e., Rajan's hypothesis) is found. Finally, the role is investigated of financial liberalisations in shaping banking stability, and we find that financial liberalisations can enhance growth and lower financial risks.
iLABMED, why now and how in the future?
Authors: Lu Hongzhou 
Published: March 2023

AbstractNowadays, public health is facing many challenges, mainly including non‐communicable diseases and communicable diseases. Communicable diseases, particularly emerging infectious diseases, have also attracted attention due to their enormous impact on public health and the global economy. The most prominent example is the current global Coronavirus Disease 2019 (COVID‐19) pandemic. The unprecedented and ongoing COVID‐19 pandemic has highlighted the necessity for readily available, accurate, and rapid laboratory medicine (LM) practices. Nevertheless, current LMs and journals in particular have a window for improvement. First, there are limited numbers of professionals available in this field compared to the other disciplines. The current status quo is that most LM manuscripts must be submitted to comprehensive journals or other journals related to the research disease. Second, most LM journals are run by laboratory personnel who are often more concerned with technical advances than with clinical needs. Lastly, several young LM scientists expressed their desire to have a dedicated platform to discuss, communicate, and publish their works on LM. We were therefore motivated to launch iLABMED, an international public forum dedicated to LMs. The establishment of iLABMED adopts the “four I” strategy, namely “Innovation,” “Intelligence,” “Integration,” and “International.” We are attempting to establish a top‐tier journal in the field of LM.
Technology for resilience amidCOVID‐19 pandemic: Narratives from small business owners in Kenya
Authors: Ndiege Joshua Rumo Arongo , Mwaura Leah Mutanu , Christopher Foster 
Published: March 2023

AbstractThe COVID‐19 pandemic has changed many aspects of the economy. The situation has notably been more challenging for small businesses in developing countries which tend to operate with limited funding and a lack of social and human capital. In these contexts, technology has been argued to be an important resource to allow businesses to adapt and recover from the crisis. In line with this narrative, the pandemic has been linked to growing technology adoption within small firms in developing countries. However, little is known about how small businesses are using such technology as part of strategies: to survive, reposition themselves in the market and potentially “spring back” from the pandemic to thrive in a fundamentally changed environment. In this study, to fill this gap we look to the concept of resilience to examine how technology was adopted to help build resilience. The study focused on small businesses in Kenya and uses in‐depth qualitative analysis to unpack the processes of adoption and use. The study findings suggest that the pandemic created an incentive for many small businesses to engage with digital technology, enabling them to stay operational. The study evidenced specific coping strategies that incorporated technology to support resilience, including exploiting demand, acquiring new capabilities, expanding existing capacities, making data‐driven decisions, fostering social networks and freezing operations. Consequently, we argue for the need to unpack the processes of technology adoption and the links between technology and economic growth in such settings. During the pandemic, small businesses have typically adopted technology to build resilience appropriate to their context.
LINC01376 promotes nasopharyngeal carcinoma tumorigenesis by competitively binding to the SP1/miR‐4757/IGF1 axis
Authors: Peng Yi , Zhang Yujie , Liu Yatian , Dong Zhen , Wang Tingting , Peng Fanyu , Di Wenyi , Zong Dan , Du Mingyu , Zhou Hongping , He Xia 
Published: March 2023

AbstractThe long non‐coding RNA (lncRNA)–microRNA (miRNA) interaction network plays a crucial part in the pathogenesis of nasopharyngeal carcinoma (NPC). Here, we discovered a relationship between LINC01376 and miR‐4757 in NPC tumor development. First, LINC01376 was abnormally overexpressed in NPC tissues and cells, and its elevated expression was associated with advanced clinical stage and shorter distant metastasis‐free survival time. Moreover, biological experiments showed that LINC01376 facilitated the proliferative, invasive, and migratory abilities of NPC cells in vitro and in vivo. Mechanistically, bioinformatics and RT‐qPCR assays revealed that LINC01376 knockdown upregulated the expression level of downstream miR‐4757, including miR‐4757 primary transcript (pri‐miR‐4757) and mature miR‐4757. Furthermore, LINC01376 competitively sponged the transcription factor SP1 and reduced its enrichment in the upstream promoter region of miR‐4757 to repress miR‐4757 expression. Finally, insulin‐like growth factor 1(IGF1) was identified as the target of miR‐4757. Rescue experiments indicated that LINC01376 accelerated NPC cell proliferation, migration, and invasion through the miR‐4757‐5p/IGF1 axis. In conclusion, the SP1/miR‐4757/IGF1 axis, which is regulated by LINC01376 in NPC deterioration and metastasis, is expected to provide new insights into the molecular mechanism of NPC carcinogenesis.
Comparative effectiveness and safety of a pharmacist‐managed protocol for the transition from intravenous to subcutaneous insulin
Authors: Gerhardt Jenna M. , Dine Serena A. , Foster David R. , Lodolo Andrew C. , McIntire Allyson M. , Peters Michael J. , Rhew Taylor A. , Walroth Todd A. 
Published: March 2023

AbstractPurposeTo evaluate the effectiveness and safety of a pharmacist‐managed protocol for transitioning critically ill patients from intravenous (iv) to subcutaneous insulin compared with a provider‐managed process.MethodsThis single‐center, retrospective, observational study included patients admitted to the medical or surgical/trauma intensive care unit who received a continuous infusion of iv insulin from January 2019 to April 2021. Patients were excluded if they were less than 18 years of age, pregnant, incarcerated, or received iv insulin for the diagnosis of diabetic ketoacidosis, hyperglycemic hyperosmolar state, calcium channel blocker or beta blocker overdose, or hypertriglyceridemia. The primary outcome was the percentage of blood glucose (BG) concentrations within the target range of 70–150 mg/dL from 0 to 48 h following transition to subcutaneous insulin. Secondary outcomes included percentage of BG concentrations within goal range following transition at 0–12 h and 12–24 h, incidence of hypo‐ and hyperglycemia, and percentage of patients requiring dose adjustments after initial transition.ResultsA total of 110 unique patients were included with 70 patients in the provider‐managed group and 40 patients in the pharmacist‐managed group. On average, pharmacists transitioned patients to 63% basal insulin based on their 24‐h total day dose of insulin. The pharmacist‐managed group achieved glycemic control in 53% of transitions at 12 h, 40% at 24 h, and 47% from 0 to 48 h, while the provider group achieved glycemic control in 25% of transitions at 12 h, 12% at 24 h, and 18% from 0 to 48 h (p < 0.001 for all time points). As for safety end points, the pharmacist‐managed group demonstrated lower rates of hypoglycemia (p = 0.001), severe hypoglycemia (p = 0.332), hyperglycemia (p < 0.001), and severe hyperglycemia (p < 0.001) compared with the provider‐managed group.ConclusionsPharmacists can effectively and safely transition critically ill patients from iv to subcutaneous insulin utilizing a standardized protocol.
The involvement of Aurora‐A and p53 in oxaliplatin‐resistant colon cancer cells
Authors: Chen Mei‐Chih , Yang Bing‐Ze , Kuo Wei‐Wen , Wu Shih‐Hsin , Wang Tso‐Fu , Yeh Yu‐Lan , Chen Ming‐Cheng , Huang Chih‐Yang 
Published: March 2023

AbstractResistance to chemotherapy is the deadlock in cancer treatment. In this study, we used wild‐type LOVO (LOVOWT), a human colon cancer cell line, and the oxaliplatin‐resistant sub‐clone LOVOOR cells to investigate the molecular mechanisms of the development of drug resistance in colon cancer. Compared with LOVOWT cells, LOVOOR cells had a high proliferation capacity and a high percentage on the G2/M phase. The expression and activation of Aurora‐A, a critical kinase in G2/M phase, were higher in LOVOOR cells than in LOVOWT cells. The results from immunofluorescence indicated an irregular distribution of Aurora‐A in LOVOOR cells. To evaluate the importance of Aurora‐A in oxaliplatin‐resistant property of LOVOOR cells, overexpression of Aurora‐A in LOVOWT cells and otherwise knockdown of Aurora‐A in LOVOOR cells were performed and followed by administration of oxaliplatin. The results indicated that Aurora‐A might contribute to the resistance of LOVOOR cells to oxaliplatin treatment by depressing p53 signaling. The specific findings in this study provide a possibility that targeting Aurora‐A might be a solution for patients who have failed oxaliplatin treatment.
Connection and alienation during the COVID‐19 pandemic: The narratives of four engineering students
Authors: McIntyre Brianna Benedict , Rohde Jacqueline , Clements Herman Ronald , Godwin Allison 
Published: March 2023

AbstractBackgroundThe COVID‐19 pandemic has highlighted, exacerbated, and caused many challenges within engineering education. At the same time, the pandemic provided opportunities for engineering educators to learn from forced change to promote strategic efforts to improve classroom engagement and connection to better support engineering students.PurposeWe leveraged students' stories to discuss ways university administrators, faculty, and instructors can better support their students during times of global crisis and beyond the current pandemic.Design/MethodWe conducted longitudinal narrative interviews with four White women engineering students from different universities in their third and fourth years. The students were selected from a larger research project because their rich and reflective stories resonated with other participant narratives, the research team, and ongoing conversations about educating during and after the COVID‐19 pandemic. Through narrative inquiry, we constructed “restoryed” vignettes and identified patterns within the four students' distinctive stories by drawing on a theoretical framework designed to examine connection and alienation.ResultsThe findings provided insights into how students were stressed and disconnected from their education in undesirable ways. The findings also provide insight into how those same students received support and maintained a connection to their institution, advisors, and instructors that educators could emulate.ConclusionsOur theoretical framework of connection and alienation proved helpful for understanding the experiences of four engineering students. Additionally, these stories provide practical examples of how faculty and staff can support student connections beyond the pandemic.