bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors associated with response to Androgen Deprivation Therapy in patients with Metastatic Prostate Cancer at the University Teaching Hospital Lusaka, Zambia
Authors: Savopoulo Vanessa A.S. , Mapulanga Victor 
Published: August 2023

Background: Prostate cancer in most cases is dependent on the presence of androgens (testosterone) produced either by the testis or adrenal gland. The major risk factors for development include aging, ethnicity and genetic predisposition. Organ confined prostate cancer is curable by surgery or radiotherapy while metastatic disease is treated by androgen deprivation therapy (ADT). ADT can be achieved medically (gonadotropin releasing hormone agonists or antagonists) or surgically (bilateral orchiectomy). A decrease in serum prostate specific antigen (PSA) is used as a marker of response to ADT. Metastatic prostate cancer has been found to be the most common cause of death in the urology department at the University Teaching Hospitals – Adult Hospital even after ADT, therefore, the aim of this study was to identify the pre-treatment factors that can be used to determine the response to ADT.
Methodology: This was a cross section study conducted at the University Teaching Hospitals- Adult Hospital and Cancer Diseases Hospital. It was carried out between December 2017 and September 2018. Patients with metastatic prostate cancer were recruited. Socio-demographic characteristics, clinical presentation and histopathological findings were elicited by detailed history and file review. PSA and Eastern Cooperative Oncology Group (ECOG) performance status score were obtained prior to ADT commencement. ADT was done and patients were scheduled for a three month post ADT review where PSA and ECOG performance status score were reobtained.
Results: 50 patients were recruited into the study. The total patient retention was 88% (n=44). The average age was 71. Majority, 89% (n=39) had some level of education; 98% (n=43) had lower urinary tract symptoms (LUTS); 11% (n=5) had paraplegia. 98% (n=43) had bone metastasis. Duration of symptoms at presentation was > 6 months in 75% (n=33) patients. ECOG score was above 1 in 75% (n=33). Initial PSA was above 100ng/ml in 75% (n=38). All patients had Gleason scores above 7. All patients had a drop in PSA after ADT. The average PSA percentage drop in men below 60 years was 80.5% whereas the average percentage drop in PSA with regards to other factors was 91.19%.
Conclusion: All patients had androgen dependant cancers. These patients also had high risk prostate cancer with initial PSA values above 100ng/ml and Gleason scores above 7. Of all the factors analysed, age below 60 years was found to be the only clinically significant factor associated with poor response to ADT.
Medical Ward In-Patient Mortality Patterns at a Tertiary Hospital in Urban Zambia: A One Year Review June 2018-June 2019
Authors: Chanda Stephen Longa , Liusha Namakando , Chansa Abidan 
Published: August 2023

Background: Very little information exists about the causes of death in Zambian Hospitals. Recording of health related vital events in Zambia is often incomplete, and thus government relies on inaccurate verbal autopsies and models to guide policy and monitor increasing amounts of donor aid given towards the eradication of specific diseases. As most developing regions of the world are undergoing gradual epidemiologic transition, inpatient hospital mortality patterns become more important in reflecting this transition.Objectives: The purpose of this study was to establish the inpatient mortality patterns among patients admitted to the adult medical wards of Kitwe Teaching Hospital between June 2018 and June 2019.Methods: The files of patients who had died between June 2018 and June 2019 were reviewed and death information extracted by a combined team of clinicians. This information was then inputted and analysed using SPSS version 16.0 for Statistical Analysis.Results: It was observed that most (n=145, 56.60%) deaths occurred within 72 hours of admission, 47% of these deaths were of Human Immune-deficiency Virus (HIV) positive patients (p=0.04). 55% of all HIV positive related mortalities occurred within 72hours of admission. There was a bimodal distribution of causes of death with deaths due to communicable diseases (n=118, 46.09%) occurring in the younger age groups (median age 36, p=0.000) and HIV positive and deaths due to noncommunicable diseases (n=138, 53.9%) occurring in the older age groups (median age 54, p=0.000) and HIV negative. HIV (n=124, 48.44%) and TB (n=54, 21.10%) were the leading communicable causes of death. Stroke (n=37, 14.50%) and heart failure (n=24, 9.40%) were leading non-communicablecauses of death. Hypertension was the most common associated cause of death (n=38, 13.80%). Overall, more men died than women (male to female ratio 1.49:1), men died at a younger age (median age 42, p=0.180) compared to women (median age 46, p=0.180).Conclusion: Most patients died within 72 hours of admission, with the young dying mainly from communicable diseases associated with HIV and the elderly from non-communicable diseases associated with hypertension.
Factors Influencing the Knowledge and Practice of Emergency Contraception among Nigerian Male Undergraduates
Authors: Ogunbode Olayinka O. , Agboola Adebayo 
Published: August 2023

Background: Unwanted pregnancies among young women is a growing reproductive health concern. Correct and consistent use of contraception will stop this ugly trend while emergency contraception (EC) can also be viewed as a 'second chance method' in preventing unwanted pregnancies and unsafe abortions. The aim of this study is to assess the knowledge and practice of emergency contraception among Nigerian male undergraduates as they are known to have risky sexual behaviours.Methodology: This was a cross sectional study involving three hundred and thirty male undergraduates from three Tertiary institutions in Ibadan. A Multi-staged random sampling technique was used to recruit participants.Results: Knowledge about EC was poor among majority (74.5%) of male undergraduates. About 55.2% of the participants were sexually active and out of which 33.9% are currently using EC. The commonly (67.5%) used EC by their partners was levonorgestrel only pill (Postinor). Participants with higher levels of education, awareness of EC, previous use or having a partner who had previouslyused EC, participants who had sex within the past 6 months and those who were willing to recommend EC to others had a better knowledge of EC, which were all statistically significant.Conclusion: Providing accurate information to improve knowledge of EC among young men could lead to an increase in the uptake of EC.
Juvenile-onset Open-Angle Glaucoma at the University Teaching Hospitals - Eye Hospital, Lusaka Zambia
Authors: Muma Kangwa I. M. , Mboni Chileshe , Mwale Consity , Muma Kachikonyo Sibande , Nyalazi , Jessie I. M , Zulu George , Malisawa Tyness S. Mumba , Zulu Righton , Mulenga Patricia , Mutati Grace Chipalo , Musonda Lillian Chinama , Kaonga Patrick , Simulundu Edgar , Michelo Charles 
Published: August 2023

Purpose: To demonstrate the socioeconomic, demographic and clinical characteristics associated with patients of juvenile-onset open- angle glaucoma (JOAG) at the University Teaching Hospitals Eye Hospital (UTHs - EH).Methods: This was a cross-sectional survey for Juvenile Open Angle Glaucoma (JOAG) conducted at the UTHs - EH in, Lusaka, Zambia from January to December 2013. All participants aged between 18 and 39 years had a full ocular examination after capturing demographic and socioeconomic information. The ocular examination included visual acuity, intraocular pressure (IOP) and cup disc ratio (CDR) and tests performed were central corneal thickness (CCT) and visual fields. Severity was graded based visual field (VF) in the worse eye using the advanced glaucoma intervention study score. Univariate and multivariate logistic regression, stratified by age group and gender, was used to determine the association between demographic factors and JOAG and between clinical factors and JOAG.Results: Of the 1625 patients recruited for the study, 309 were POAG patients. Of the 309 POAG patients, 140 aged 20 to 39 years old had bilateral JOAG. The distribution of the 140 participants was 98 (70.9%) females and 42 (29.4%) males. Thirteen (9.3 %) were aged 20 – 24 years, 29 (20.7%) 25 – 29 years, 44 (31.4%) 30 – 34 years, and 54 (38.6%) 35 – 39 years. The mean age of the patients was 25.1 ± SD 8.7 years. The prevalence of JOAG was 8.6%
Application of Kegel Gymnastics in Reducing Urinary Incontinence in the Elderly in Gampong Lamleuot, Kuta Cot Glie District, Aceh Besar
Authors: Rahmiati Cut , Afrianti Novi 
Published: August 2023

The elderly are someone who has reached the age of 60 years and over, where in old age a person has experienced various declines in system function, as well as changes in body structure, one of which is a change in the structure of the urinary system and has weakened pelvic floor muscles and decreased bladder capacity, so the elderly are very vulnerable to urinary incontinence. Urinary incontinence is a bladder sphincter defect or neurological dysfunction that causes loss of control over urination. Thus causing a person to experience physical, psychological, social, and economic problems that affect the quality of life of the elderly, one of the treatments for urinary incontinence in the elderly is by practicing Kegel exercises. The purpose of this study was to find out the picture of the application of Kegel exercises in reducing urinary incontinence in the elderly with urinary incontinence. This research method is a case study with 2 (two) research subjects, which was carried out in Gampong Lamleuot, Kuta Cot Glie District, Aceh Besar Regency on March 9-20, 2023. The instruments used are SOPs for Kegel exercises, observation sheets and Resived Urinary Incontinence Scale (RUIS) questionnaires. The results showed a decrease in the level of incontinence in the elderly after the application of Kegel exercises, thus it is hoped that elderly gymnastics can be used as one of the therapies in reducing the level of urinary incontinence in the elderly.
Sanctieovertredingen als ‘EU-misdrijf’: een stap dichter bij uniforme Europese handhaving?
Authors: Mooring E.R. , Wever E.S.J. , Kodrzycki T.J. 
Published: August 2023

Sanctieovertredingen als ‘EU-misdrijf’: een stap dichter bij uniforme Europese handhaving?
Het voorstel van de Europese Commissie voor een richtlijn op het gebied van de strafbaarstelling van schendingen van beperkende maatregelen en de sanctionering daarvan is een belangrijke stap in de richting van harmonisatie van de handhaving van EU-sancties. Het is wat ons betreft echter de vraag of het voorstel in staat is de beoogde doelstellingen te bereiken. Zo behouden de lidstaten veel vrijheid bij omzetting van de richtlijn in nationale regelgeving en ligt er ook vooral een groot probleem in (het prioriteren) van handhaving en vervolging in de lidstaten.
Autopercepção negativa em saúde bucal da população quilombola brasileira
Authors: Sobrinho Adriano Referino da Silva , De Carvalho Ana Laura Vilela , Bezerra Nathália Larissa , Ramos Leticia Francine Silva , Marques Maiara Bernardes , Correia Ana Carolina de Carvalho , Costa Moan Jéfter Fernandes , Sette-de-Souza Pedro Henrique 
Published: August 2023

Diante da importância da autopercepção para o reconhecimento de condições de saúde bucal numa população, torna-se importante levantar esse indicador para embasar futuras políticas públicas. Identificar a prevalência da autopercepção negativa em saúde bucal dos indivíduos pertencentes às comunidades quilombolas brasileiras. Trata-se de uma revisão integrativa da literatura com pergunta norteadora “Qual a prevalência da autopercepção negativa em saúde bucal dos indivíduos pertencentes às comunidades quilombolas brasileiras?”. A estratégia de busca foi conduzida nas bases de dados Biblioteca Virtual em Saúde (BVS), Scielo, PubMed, Web of Science, Science Direct, Scopus e Embase no mês de julho de 2023. A busca foi pareada e os resultados sintetizados. A amostra final foi composta por oito estudos, concentrados na região Sudeste, de delineamento predominantemente transversal e com amostras variáveis de crianças, adolescentes, adultos e idosos. A prevalência da autopercepção negativa em saúde bucal variou entre 23,5% e 100%. A autopercepção negativa é bastante variável dentre a população quilombola brasileira e esta deve ser indicador levado em consideração na elaboração das futuras políticas de saúde bucal direcionadas a esses povos.
Unlocking Opportunities: Tourism Ship Financing Through Leasing Agreements for Micro, Small, and Medium Businesses in Indonesia
Authors: Badriyah Siti Malikhatun , Suharto R. , Saraswati Retno , Marjo  
Published: August 2023

Objective: This research explores the prospects of leasing agreements as a financing solution for tourist boats for MSMEs, considering the vast potential of marine tourism in Indonesia. Despite the potential benefits of leasing agreements, no specific regulations govern them, resulting in deviations from leasing principles and limited understanding among stakeholders.

Methods: The study adopts the triangle legal pluralism approach and focuses on the Special Capital District of Jakarta and Labuan Bajo as significant marine and tourism industry hubs. Primary data collection includes interviews, observations, and secondary data from legal documents and literature. The analysis employs deductive and inductive logic and triangulation for validation.

Result: According to this study, leasing agreements can help Indonesian tourism MSMEs finance tourist boats. Indonesia's maritime tourist business has great potential due to its archipelago and natural resources. However, MSMEs need help to acquire capital to ensure tourist boat growth, impacting tourism services and experiences. The following suggestions aim to unlock potential and promote sustainable tourism growth: Include Rental Contract Laws: Due to the industry's lack of rules, leasing agreements vary and cause disputes. Implementing lease agreement guidelines will provide legal certainty, protect lessors and lessees, and ensure fair and transparent business practices; Because many need help understanding, outreach, and education must increase. Leasing Agreements must broaden and organize outreach to educate MSMEs, business actors, and the public about leasing's benefits and processes.

Suggestions: Ultimately, this research aims to provide valuable insights for policymakers, businesses, and academics to promote tourism ship financing through leasing agreements to grow the Indonesian tourism industry.
Service Quality and Institutional Image as Predictors of Customer Satisfaction in Municipalities of Perú
Authors: Romero-Carazas Rafael , Ochoa-Tataje Freddy Antonio , Mori-Rojas Gina , Vilca-Cáceres Vilma Amalia , Gómez-Cáceres Felipe Yony , Carpio-Delgado Fabrizio del , Zárate-Suárez Julio Samuel , Espinoza-Casco Roque Juan 
Published: August 2023

Objective: This research aimed to analyse the predictability of service quality and institutional image for customer satisfaction in municipalities in Peru.

Theoretical framework: In this sense, one of the most important links between differentiation of services that can only be recognised and appreciated by the customer and competitive advantages or institutional image has become essential parts of organisations; it is the quality of services provided by public organisations such as municipalities that are under scrutiny and subject to evaluation and satisfaction of their users.

Methodology: It was based on a quantitative, prospective correlational approach, with a sample of 352 users of municipalities in Peru.

Results: An R2 of 0.460 was obtained, and the effect size was calculated with a coefficient of 0.851, which is considered a very high parameter above 0.350. The calculation of the significant statistical power resulted in a value of 1, which is considered very high. Furthermore, the standardisation coefficients have shown that service quality and institutional image are relevant, positive and significant predictors of customer satisfaction in Peruvian municipalities. Additionally, service quality was found to be the predominant predictor (beta=0.654).

Conclusion: This study showed that there is a relationship between users' perceptions of service quality and institutional image and its predictive correspondence on their satisfaction. Citizens' satisfaction with the services provided by Peruvian municipalities was influenced to a greater extent by the public image of the entities.
Originality/value: Service quality and institutional image influence customer satisfaction with Peruvian state organisations.
Leverage Analysis, Investment Opportunity Set, and Ownership of Company Value
Authors: Tangngisalu Jannati , Halik Abdul , Marwan  , Jumady Edy 
Published: August 2023

Purpose: This study examines the effect of leverage, investment opportunity sets, and managerial ownership on firm value with dividend policy as an intervening variable in manufacturing companies listed on the Indonesia Stock Exchange.

Theoretical framework: The general framework of this research includes two theories on it firstly, Signaling Theory which is an action taken by management to guide investors about how management views the company's prospects in the future (Taleb, 2019), and secondly, Dividend Policy Theory is part of the company's spending decisions, primarily related with the company's internal spending, this is because the size of the dividends distributed will affect the size of retained earnings. Retained earnings are one of the company's internal funding sources (Lumapow & Tumiwa, 2017).

Methodology: We use a quantitative approach with a survey approach. The population in this study are all manufacturing companies listed on the Indonesia Stock Exchange (IDX) during 2018-2020. In this study, the sample was taken using a purposive sampling method. The purposive sampling method limits the selection of sampling based on specific criteria.

Findings: This study found a positive and significant relationship between leverage and investment opportunity sets on company value in manufacturing companies listed on the Indonesia Stock Exchange in 2018-2020. Meanwhile, managerial ownership and dividend policy have a positive and insignificant effect on the company's corporate value in manufacturing companies listed on the Indonesia Stock Exchange in 2018-2020. Leverage does not have a significant adverse impact on firm value through dividend policy.

Research, Practical & Social implications: This study analyzes and evaluates the Effect of Leverage on Firm Value. That is, companies that have a high level of leverage can increase firm value because investors assume that the value of companies that have high debt are large-scale companies and the influence of dividend policy on substantial value, namely the use of debt, can increase the firm value if the profits are more significant than costs. Used at the time of use of debt.

Originality/value: The findings show a positive and significant relationship between leverage and investment opportunity sets on company value in manufacturing companies listed on the Indonesia Stock Exchange in 2018-2020. Influence does not have a significant adverse effect on firm value through dividend policy. Dividend policy cannot mediate the impact of power on solid value.
External Bremsstrahlung Studies on Films of Lead Monoxide Filled Polycarbonate Composite
Authors: Kandagal V. A. , Lobo B. 
Published: August 2023

The development of high-Z (high atomic number) radiation shielding materials is vital in order to protect personnel who work with harmful gamma radiation sources. At the same time, the emission of external bremsstrahlung (EB) radiation in those shielding materials when the radiation source emits beta particles as well as gamma radiation is also of prime concern.The production of EB in films of lead monoxide (PbO) loaded polycarbonate (PC) composite at eleven different filler levels (FLs) varying, in terms of weight fraction, from 0.0 % up to 10.0 % were investigated experimentally by using beta particles from strontium-90/yttrium-90 (90Sr/90Y) radioactive source. A nonlinear relation is observed between EB intensity and target thickness. The effective atomic numbers of the prepared PbO-filled PC composite films (at different FLs) were determined via EB measurements, followed by calculations, and the values obtained were compared with the modified atomic numbers which were determined for the same composite films (at different FLs) using the Markowicz and Van Grieken equation, and it was found that they are in good agreement. Finally, the atomic number dependence of EB in these composite films (PbO-filled PC composites) has been studied. It is obtained that the intensity of EB spectra depends on the square of the atomic number of the target material.
Unraveling the Hybridization Process in CeAgSb2 Kondo Lattice
Authors: Pei Yunhe , Yang Surui , Qi Jingbo 
Published: August 2023

We present a comprehensive investigation utilizing ultrafast optical pump-probe spectroscopy to elucidate the intricate quasiparticle dynamics in the CeAgSb2 single crystal. Through our experimental endeavors, a nuanced two-phase evolution in the hybridization phenomena linking localized f moments and conduction electrons has been unveiled. This intricate process is manifest in two distinct manifestations: firstly, the discernible manifestation of hybridization fluctuations spanning the temperature range of approximately 150 K (denoted as T†) down to approximately 65 K (referred to as T*); secondly, the notable emergence of a collective hybridization phenomenon below the critical temperature, T*, as indicated by the onset of an indirect gap in the electronic structure. These discerning observations provide invaluable insights into the interplay of electronic configurations as a function of temperature in CeAgSb2, shedding light on its unique properties and behaviors.
Aplicaciones de la fluorescencia con verde de indocianina en anastomosis de cirugía colorrectal: una revisión bibliográfica.
Authors: Ordoñez-Hidalgo Emily Ximena , Verdugo-Tapia Juan Carlos 
Published: August 2023

Introducción: Durante una cirugía intestinal uno de los desafíos más importantes es mantener la vitalidad intestinal determinando su viabilidad para evitar complicaciones como resección intestinal (1). La fuga anastomótica (LA) sigue siendo la complicación más temida, con una frecuencia de hasta el 30% en centros de no gran volumen (2). La angiografía con fluorescencia ICG podría ser un método objetivo y no invasivo para evaluar la viabilidad intestinal y determinar correctamente la extensión de la isquemia (3). Objetivo general: Analizar la eficacia de la aplicación de la fluorescencia verde de indocianina en la cirugía de colon y recto mediante una revisión bibliográfica. Metodología: Revisión bibliográfica tipo narrativa en estudios, metaanálisis, revisiones sistemáticas, ensayos clínicos controlados, estudios de cohortes, revisiones bibliográficas que reporten el papel de la fluorescencia verde de indocianina en la cirugía colorrectal desde 2018 a 2023, en los idiomas inglés y español. Resultados esperados: Se espera eficaz la aplicación de la fluorescencia verde de indocianina en la cirugía de colon y recto.