bluuebunny/crossref_metadata_2025_split huggingface dataset:
Childhood Poisoning - Associated Factors and Clinical Profile in a Tertiary Care Hospital
Authors: Parvin Most Firoza , Ara Chaman , Momotaj Tanjila , Mia Sanaul Haque , Uddin Md Belal , Begum Fardoushi , Rashid Md Mamun Ur 
Published: January 2023

Background: Acute poisoning is a common medical emergency in the pediatric unit. It is a common preventable cause of morbidity and mortality in children. Most of the poisoning in children less than five years of age is accidental. This study aimed to determine the associated factors and clinical profile of childhood poisoning.
Material & Methods: A cross-sectional descriptive study was carried out among 69 children aged six months to 12 years with a history of poisoning over six months. History, clinical examination, and details of the poisoning were obtained by using a structured questionnaire during admission. Analysis was done through standard statistical tests.
Result: Among the 69 children of poisoning, 92.8% were accidental, and 7.2% were suicidal. Most cases (79.7%) were from the 6 - 59 months age group with male-female ratio 1.7:1. Most of the fathers (65.2%) and mothers (75.4%) had primary education, and 75.4% were poor. The most common cause of the poisoning was insecticide (60.9%), and the poison was stored at an available site (91.3%) in an unsealed container (47.8%). Accidental poisoning was more common in younger age group (<5 years) in male (70.31%) patients with normal family relationships (78.1%), whereas suicidal poisoning was more common in older age group (>10 years) in females (80%) patient with h/o familial disharmony (60%).
Conclusion: Insecticides and kerosene were the common cause of poisoning. Most of the materials were stored in an unsafe place and stored in an attractive bottle. Poison should be stored in a safe home with a sealed container. Simple and active family preventive measures can reduce accidental poisoning.
TAJ 2022; 35: No-2: 75-82
Impact of Infant and Young Child Feeding Practices on the Nutritional Status of Children in Northern Bangladesh
Authors: Ali Md Yousuf , Das Mrinal Kanti , Sharmin Laila Shamima , Islam Md Manirul , Karim Md Rezaul , Mia Md Sanaul Haque , Uddin Md Belal 
Published: January 2023

Background: Proper feeding practices are essential for attaining and maintaining optimum nutrition, health, and development of infants and children. Exclusive breastfeeding during the first six months of life and continued breastfeeding for two years, together with age-appropriate, nutritionally adequate complementary feeding initiated after six months of age, are optimum Infant and Young Child Feeding (IYCF) practices. However, often many aspects of infant and young child feeding practices are not optimum, with serious consequences for the child.
Objective: To determine the impact of Infant and Young Child Feeding (IYCF) practices on the nutritional status of children. Materials and Method: This Cross-sectional descriptive type of study was conducted among 314 children from 6 months to 24 months of age at the Pediatric Outpatient Department and EPI center of Rajshahi Medical College Hospital during the period of January 2017 to December 2018. Collected data were analyzed by using 'SPSS version 16.
Result: Among 314 children exclusive breastfeeding (EBF) rate was 68.2% for the first six months, and timely started complementary feeding was 58.5% of cases. In 214 exclusive breastfed infants, only 4.7% and 1.4% of children were moderate to severely wasted and stunted, respectively. On the other hand, among 97 infants who were not exclusively breastfed, the percentage of moderate to severe wasting and stunting was 11.4% and 13.4%, respectively. Among the 175 timely started complementary feeding children, only 12% and 6% were moderate to severely underweight and wasted, respectively, no one was stunted, but among the inappropriately started complementary children, 20.2%, 12.5%, and 12.8% were moderately to severely underweight, wasted and stunted respectively.
Conclusion: Most of the children who were given exclusive breastfeeding in the first six months and started complementary food at an appropriate time after six months had normal nutritional status. Both moderate to severe stunting and wasting were common in those children who were non-exclusively breastfed and started complementary feeding either early or late.
TAJ 2022; 35: No-2: 83-91
Noncompliance to Antihypertensive Medication in Patients with Essential Hypertension attending Dhaka Medical College Hospital
Authors: Rashid Md Mamun ur , Haque Md Mohaimenul , Islam Md Shafiqul , Parvin Most Firoza , Kahhar Azizul 
Published: January 2023

Introduction: Medication noncompliance is a necessary but neglected factor for the negative cardiovascular outcome. Despite various studies on the issue, the factors behind noncompliance still need to be explored properly. Therefore, this study was conducted to determine the magnitude and factors associated with noncompliance with antihypertensive Medication.
Materials and Methods: This is a cross-sectional study that was conducted on 200 hypertensive patients in Dhaka Medical College Hospital for six months. Patients were included by purposive sampling, aged 18-70 years, and the duration of diagnosis of at least three months. In addition, demographic data, hypertension diagnosis, antihypertensive drugs, factors related to noncompliance, knowledge of hypertension, perception, and family support were included in the questionnaire.
Result: About 85% of the patients were non-compliant with treatment in their course of illness, and the main reason behind it was forgetfulness (48.2%). Other factors were inability to buy, side effects, busy schedule, intentionally, bored, and traveling. The highest prescribed drug was beta blockers (41%). Eighty percent of the patients knew that uncontrolled hypertension could lead to stroke, and 54% knew it could lead to heart disease. The majority (87.5%) of the participant went for follow-up only when they felt hypertensive. Regarding perception, 63% of patients felt hypertension is not a curable disease. Furthermore, though all patients were asked for follow-up by their physician, 94% missed their follow-up.
Conclusion: Despite the availability of various types of effective antihypertensive drugs, many patients experience difficulty controlling hypertension due to noncompliance. Patient and family member education efficiently prevented many factors behind the disobedience. However, further studies with large sample sizes in multiple centers could explain this more precisely.
TAJ 2022; 35: No-2: 103-110
Redacción académica y consideraciones gramaticales y ortográficas
Authors: Zelada-Vásquez María 
Published: January 2023

La finalidad de este artículo es registrar información sobre el conocimiento del tema, qué importancia tiene este tema en el siglo XXI, qué enfoque tiene nuestro país respecto del tema, identificación de contradicciones de algunas entidades e investigadores sobre el tema por último identificar variable asociada al tema de estudio; además que permita responder a las preguntas de investigación tales como; cuánto se conoce sobre el tema y sobre la población universitaria con más dificultad en redacción, para ello se utilizó la metodología de estudio de revisión bibliográfica en revistas científicas teniendo en cuenta artículos relacionados con las variables, por lo que la búsqueda bibliográfica es de fuentes confiables, se consideró la técnica de lectura veloz y crítica de los resúmenes y resultados de cada investigación necesarias para responder a la investigación, se consideró estudios de los seis últimos años, como resultado de estas consultas se analizó 60 artículos de los que 20 contextualizan las reglas gramaticales como ortográficas y 40 tratan de la redacción académica; estos estudios coinciden que la redacción no es homogénea en los estudiantes demostrándose en diferentes estudios que existe diferencia en la calidad de redacción por facultades, por lo que se coincide en reforzar estrategias de redacción académica teniendo como base la utilización de las reglas gramaticales y ortográficas.
Cultura organizacional y su incidencia en el clima laboral de la Cooperativa Intercantonal de Transporte Ayacucho, provincia de Manabí
Authors: Vera-Briones María , Mendoza-Vera Cristina 
Published: January 2023

La interacción entre la cultura organizacional y el clima laboral se basa específicamente en que las políticas, misión, valores que se manejen dentro de la empresa, es decir, la cultura incide en la conducta, estos temas tienen su importancia en las entidades para evidenciar el comportamiento del talento humano y lo que este contribuye de forma positiva o negativa en los resultados y posicionamiento de las empresas. El objetivo de la presente investigación se centró en analizar la incidencia de la cultura organizacional en el clima laboral de la Cooperativa Intercantonal de Transporte Ayacucho, provincia de Manabí. Se aplicó un enfoque metodológico cuantitativo por cuanto se trató de comprender frecuencias, patrones a seguir por parte del personal que labora en la empresa; las técnicas utilizadas para la presente investigación fue la encuesta aplicada al personal y la observación directa en la organización objeto de estudio. Los resultados que se derivan de esta investigación evidencian que la cultura organizacional y el clima laboral de la Cooperativa están basados en cualidades, principios e ideales regidos al reglamento interno de la misma. Se puede concluir mencionando que si bien es cierto que dentro de la institución existe una buena cultura organizacional y un buen clima laboral se deberían mejorar procesos que ayuden al logro de los objetivos propuestos.
The effects of nutritional level and body condition score on cytokines in seminal plasma of beef bulls
Authors: Harrison Taylor D. , Chaney Elizabeth M. , Brandt Kiernan J. , Ault-Seay Taylor B. , Payton Rebecca R. , Schneider Liesel G. , Strickland Lew G. , Schrick F. Neal , McLean Kyle J. 
Published: January 2023

IntroductionHigh quality semen is essential for reproductive efficiency. Nutrition and environmental factors impact the ejaculate components, like cytokines, that are essential for pregnancy establishment. We hypothesized that differing nutritional periods and body condition scores would affect seminal plasma cytokine concentrations of bulls.MethodsMature Angus bulls (n=11) were individually housed and randomly assigned to either over-fed (n=5) or restricted (n=6) treatment pathways. Bulls were fed different volumes of a single ration creating 8 individual treatment periods. Body weight and body condition scores were taken every 14 d to manage intake volumes. Ejaculates were collected every 84 d to determine seminal plasma cytokine profiles. A complete randomized design was used to evaluate seminal plasma cytokines after each nutritional treatment. Initial cytokine concentrations and volume of the ejaculate were included as covariates.ResultsAll cytokines returned to initial concentrations following maintenance treatments at an ideal body condition score of 6. Nutritional treatments affected (P ≤ 0.05) IFN-γ, IL-8, MIP-1α, MIP-1β, TNF-α, IL-1β, and VEGF-A. However, TNF-α, IFN-γ, and MIP-1α had the greatest impact on cytokine profile.DiscussionNutritional levels and adiposity altered seminal plasma cytokine concentrations which could potentially impact the inflammatory balance of the uterus and the immune responses necessary for pregnancy establishment.
Versatile electrical stimulator for cardiac tissue engineering—Investigation of charge-balanced monophasic and biphasic electrical stimulations
Authors: Gabetti Stefano , Sileo Antonio , Montrone Federica , Putame Giovanni , Audenino Alberto L. , Marsano Anna , Massai Diana 
Published: January 2023

The application of biomimetic physical stimuli replicating the in vivo dynamic microenvironment is crucial for the in vitro development of functional cardiac tissues. In particular, pulsed electrical stimulation (ES) has been shown to improve the functional properties of in vitro cultured cardiomyocytes. However, commercially available electrical stimulators are expensive and cumbersome devices while customized solutions often allow limited parameter tunability, constraining the investigation of different ES protocols. The goal of this study was to develop a versatile compact electrical stimulator (ELETTRA) for biomimetic cardiac tissue engineering approaches, designed for delivering controlled parallelizable ES at a competitive cost. ELETTRA is based on an open-source micro-controller running custom software and is combinable with different cell/tissue culture set-ups, allowing simultaneously testing different ES patterns on multiple samples. In particular, customized culture chambers were appositely designed and manufactured for investigating the influence of monophasic and biphasic pulsed ES on cardiac cell monolayers. Finite element analysis was performed for characterizing the spatial distributions of the electrical field and the current density within the culture chamber. Performance tests confirmed the accuracy, compliance, and reliability of the ES parameters delivered by ELETTRA. Biological tests were performed on neonatal rat cardiac cells, electrically stimulated for 4 days, by comparing, for the first time, the monophasic waveform (electric field = 5 V/cm) to biphasic waveforms by matching either the absolute value of the electric field variation (biphasic ES at ±2.5 V/cm) or the total delivered charge (biphasic ES at ±5 V/cm). Findings suggested that monophasic ES at 5 V/cm and, particularly, charge-balanced biphasic ES at ±5 V/cm were effective in enhancing electrical functionality of stimulated cardiac cells and in promoting synchronous contraction.
SnS@C nanoparticles anchored on graphene oxide as high-performance anode materials for lithium-ion batteries
Authors: Mei Jing , Han Jinlu , Wu Fujun , Pan Qichang , Zheng Fenghua , Jiang Juantao , Huang Youguo , Wang Hongqiang , Liu Kui , Li Qingyu 
Published: January 2023

Tin (II) sulfide (SnS) has been regarded as an attractive anode material for lithium-ion batteries (LIBs) owing to its high theoretical capacity. However, sulfide undergoes significant volume change during lithiation/delithiation, leading to rapid capacity degradation, which severely hinders its further practical application in lithium-ion batteries. Here, we report a simple and effective method for the synthesis of SnS@C/G composites, where SnS@C nanoparticles are strongly coupled onto the graphene oxide nanosheets through dopamine-derived carbon species. In such a designed architecture, the SnS@C/G composites show various advantages including buffering the volume expansion of Sn, suppressing the coarsening of Sn, and dissolving Li2S during the cyclic lithiation/delithiation process by graphene oxide and N-doped carbon. As a result, the SnS@C/G composite exhibits outstanding rate performance as an anode material for lithium-ion batteries with a capacity of up to 434 mAh g−1 at a current density of 5.0 A g−1 and excellent cycle stability with a capacity retention of 839 mAh g−1 at 1.0 A g−1 after 450 cycles.
Gum katira-silver nanoparticle-based bionanocomposite for the removal of methyl red dye
Authors: Saruchi  , Kumar Vaneet , Bhatt Diksha , El-Serehy Hamed A. , Pandey Sadanand 
Published: January 2023

The present study aimed to synthesize gum katira-silver nanoparticle-based bionanocomposite. Different characterization techniques were used to analyze the synthesized bionanocomposite, such as Fourier transform infrared (FTIR) spectroscopy, field emission scanning electron microscopy (FESEM), thermo-gravimetric analysis (TGA), and transmission electronic microscopy (TEM). AgNPs were formed and were 6–20 nm in size. Thermo-gravimetric analysis showed that synthesized nanocomposites are more thermally stable than gum katira. All the reaction conditions, such as time, temperature, pH, solvent, amount of nanoparticles, the concentration of the initiator, crosslinker, and monomer were optimized with respect to swelling. The results showed that the highest percentage swelling (Ps) of Gk-cl-poly(AA) was 796%, and 867% of AgNPs were imbibed by Gk-cl-poly(acrylic acid)-AgNPs. Synthesized bionanocomposite was used as an adsorbent material for the adsorption of methyl red (MR) dye. The effects of different reaction conditions were also optimized to attain maximum adsorption of MR dye. The maximum dye adsorption through Gk-cl-poly(AA)-AgNPs bionanocomposite was 95.7%. Diverse kinetic and isotherm models were used to study the adsorption data. The R2 value was established as 0.987 and k2 was .02671. The greater R2 value of second-order kinetics over first-order kinetics suggested that MR adsorption by nanocomposite is best explained by pseudo-second-order kinetics, indicating that dye adsorption occurred through chemisorption. The R2 value was determined to be .9954. The correlation coefficient values of Gk-cl-poly(AA)-AgNPs were best fitted by the Freundlich adsorption isotherm. Overall, synthesized bionanocomposite is a proficient material for removing of MR dye from wastewater.
Comparative genome analysis reveals high-level drug resistance markers in a clinical isolate of Mycobacterium fortuitum subsp. fortuitum MF GZ001
Authors: Alam Md Shah , Guan Ping , Zhu Yuting , Zeng Sanshan , Fang Xiange , Wang Shuai , Yusuf Buhari , Zhang Jingran , Tian Xirong , Fang Cuiting , Gao Yamin , Khatun Mst Sumaia , Liu Zhiyong , Hameed H. M. Adnan , Tan Yaoju , Hu Jinxing , Liu Jianxiong , Zhang Tianyu 
Published: January 2023

IntroductionInfections caused by non-tuberculosis mycobacteria are significantly worsening across the globe. M. fortuitum complex is a rapidly growing pathogenic species that is of clinical relevance to both humans and animals. This pathogen has the potential to create adverse effects on human healthcare.MethodsThe MF GZ001 clinical strain was collected from the sputum of a 45-year-old male patient with a pulmonary infection. The morphological studies, comparative genomic analysis, and drug resistance profiles along with variants detection were performed in this study. In addition, comparative analysis of virulence genes led us to understand the pathogenicity of this organism.ResultsBacterial growth kinetics and morphology confirmed that MF GZ001 is a rapidly growing species with a rough morphotype. The MF GZ001 contains 6413573 bp genome size with 66.18 % high G+C content. MF GZ001 possesses a larger genome than other related mycobacteria and included 6156 protein-coding genes. Molecular phylogenetic tree, collinearity, and comparative genomic analysis suggested that MF GZ001 is a novel member of the M. fortuitum complex. We carried out the drug resistance profile analysis and found single nucleotide polymorphism (SNP) mutations in key drug resistance genes such as rpoB, katG, AAC(2')-Ib, gyrA, gyrB, embB, pncA, blaF, thyA, embC, embR, and iniA. In addition, the MF GZ001strain contains mutations in iniA, iniC, pncA, and ribD which conferred resistance to isoniazid, ethambutol, pyrazinamide, and para-aminosalicylic acid respectively, which are not frequently observed in rapidly growing mycobacteria. A wide variety of predicted putative potential virulence genes were found in MF GZ001, most of which are shared with well-recognized mycobacterial species with high pathogenic profiles such as M. tuberculosis and M. abscessus.DiscussionOur identified novel features of a pathogenic member of the M. fortuitum complex will provide the foundation for further investigation of mycobacterial pathogenicity and effective treatment.
Higher-order transformations for the generation of synchronization infrastructures in blended modeling
Authors: Latifaj Malvina , Ciccozzi Federico , Mohlin Mattias 
Published: January 2023

IntroductionBlended modeling aims at boosting the development of complex multi-domain systems by enabling seamless multi-notation modeling. The synchronization mechanisms between notations are embodied in model transformations. Manually defining model transformations requires specific knowledge of transformation languages, and it is a time-consuming and error-prone task. Moreover, whenever any of the synchronized languages or notations evolves, those transformations become obsolete.MethodsIn this paper, we propose an automated solution for generating synchronization transformations in an industrial setting.ResultsThe approach entails i) the specification of mapping rules between two arbitrary domain-specific modeling languages leveraging a mapping modeling language, appositely defined for this purpose, and ii) the automatic generation of synchronization model transformations driven by the mapping rules.DiscussionWe validated the proposed approach in two use cases. Although our main goal was to provide a solution for synchronization between graphical and textual notations of UML-RT state machines, the proposed approach is language- and notation-agnostic.
A glimpse of the long view: Human attitudes to an established population of Eurasian beaver (castor fiber) in the lowlands of south-east England
Authors: Oliveira Sara , Buckley Phil , Consorte-McCrea Adriana 
Published: January 2023

IntroductionThe Eurasian beaver (Castor fiber) is a native species to Britain that after being absent for 400 years has been restored to the English countryside. The first beavers were released into a reserve in Kent in 2001/02, making this one of the first beaver release areas in the UK. This paper examines attitudes towards beaver presence in the landscape as well as public perception of beaver benefits and impacts with respect to the environment and human society.MethodsQualitative questionnaires were utilised to investigate factors influencing social attitudes and support for beaver reintroduction, as well as the relationship between sociodemographic variables and attitudes. Inhabitants of Kent and its immediate surroundings were surveyed during June and July of 2020 (n=407) with a focus on three interest groups – environmentalists, farmers and the general public.ResultsPerceptions included mostly beneficial impacts on nature and biodiversity, whereas less positive impacts were associated with economics, agriculture and fisheries. In general, local attitudes towards beavers were positive, mainly sustained by feelings of liking this wildlife species and valuing their presence. People´s attitudes positively influence willingness to support the reintroduction of beavers. Twenty years after their initial release, results indicate broad support for the beaver reintroduction in Kent and people´s tolerance of beavers. The majority of respondents were in favour of nonintrusive management techniques to mitigate beavers’ undesirable impacts.DiscussionThese findings suggest the need to develop an optimal management strategy that incorporates public views and gives advice on the best approach to manage this wildlife species. This research provides theoretical and practical underpinning for beaver management and conservation in Britain.