bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis Implementasi Strategi Dots (Directly Observed Treatment Short-Course) sebagai Pengendalian Tuberkulosis: Systematic Review
Authors: Dwiyovita Rizka , Kartasurya Martha Irene , Nurjazuli Nurjazuli 
Published: May 2023

ABSTRACT Indonesia is one of the countries with the highest burden of TB in the world. The DOTS strategy has been applied to control TB disease, but the implementation of the DOTS strategy has not been optimal due to the obstacles that have arisen. To analyze the implementation of DOTS strategy as tuberculosis control. This research is a systematic literature review using indexed articles on Google Scholar, Science Direct, Pub Med, and Garuda. Articles were selected using PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analyses). Analysis of article quality using the Critical Appraisal Skills Program (CASP). Eight articles were obtained that were in accordance with the research, indicating that the implementation of the DOTS strategy as tuberculosis control on political commitment in terms of funding, case detection, drug taking supervisor (PMO), as well as recording and reporting has not run optimally, while the drug distribution has been going well. Implementation of the DOTS strategy can run optimally by increasing cross-sectoral collaboration in tuberculosis control. Keywords: Directly Observed Treatment Short-Course Strategy, Qualitative, Tuberculosis Control. ABSTRAK Indonesia menjadi salah satu negara yang memiliki beban tertinggi TB di Dunia. Telah diterapkan strategi DOTS untuk penanggulangan penyakit TB, akan tetapi implementasi strategi DOTS belum optimal disebabkan oleh adanya hambatan yang muncul. Untuk menganalisis implementasi strategi DOTS sebagai pengendalian tuberkulosis. Penelitian ini merupakan kajian pustaka sistematik dengan menggunakan artikel terindeks pada Google Scholar, Science Direct, Pub Med, dan Garuda. Artikel yang dipilih menggunakan PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analyses). Analisis kualitas artikel menggunakan Critical Appraisal Skills Program (CASP). Diperoleh delapan artikel yang sesuai dengan penelitian, menunjukkan bahwa implementasi strategi DOTS sebagai pengendalian tuberkulosis pada komitmen politik dalam hal pendanaan, deteksi kasus, pengawas minum obat (PMO), serta pencatatan dan pelaporan belum berjalan optimal, sedangkan pada pendistribusian obat sudah berjalan baik. Implementasi strategi DOTS dapat berjalan optimal dengan meningkatkan kerjasama di lintas sektor dalam pengendalian tuberkulosis. Kata Kunci: Directly Observed Treatment Short-Course Strategy, Kualitatif, Pengendalian Tuberkulosis.
Dry-column Vacuum Chromatographic Removal of Hg2+ from Wastewater Based on an Acridino-crown Ether-modified Spherical Silica Gel Adsorbent
Authors: Vezse Panna , Kalóczkai János Attila , Ster Dániel , Bezúr László , Golcs Ádám , Huszthy Péter , Tóth Tünde 
Published: May 2023

Dry-column vacuum chromatographic technique is introduced for remediation of wastewater for the first time. A previously prepared chemically modified silica gel containing covalently immobilized Hg2+-selective acridino-crown ether selector molecules was used as an adsorbent. Removal of Hg2+ from highly contaminated river water was carried out to study practical applicability. Adsorption capacity, preconcentration factor, pH-sensitivity and selectivity in separation were determined. The adsorbent proved to be outstanding in selectivity, only Ag+ and Cu2+ interfered among 29 cations, was inert toward organic contaminants, exhibited regenerability and pH-independency between 3.0 ≤ pH ≤ 7.0. The proposed method showed a moderate efficiency in both adsorption (32 mg Hg2+ / 1 g adsorbent) and preconcentration (preconcentration factor of 100). A maximum 10 L of wastewater / 1 g adsorbent ratio is recommended as an upper limit for applicability. The described method showed a unique robustness and simplicity compared to conventional ion-chromatographic methods and an improved selectivity over physical interaction- or simple functional group-based adsorptions.
СЛІДАМИ ПОРОЖНЕЧІ: АРХІВНІ ФІЛЬМИ СЕРГІЯ ЛОЗНИЦІ ЯК АУДІОВІЗУАЛЬНІ UNIVERSALGESCHICHTE
Authors: Ребгандл Бертольд 
Published: May 2023

Фільм Сергія Лозниці «Бабин Яр. Контекст» (2021) доволі чітко демонструє схему перипетії, оскільки відтворює події німецької окупації Радянської України у 1941-1944 роках та її наслідки. Перипетійна структура часто включає події, про які розповідається (або які навіть насправді відбуваються) двічі, з перспективи «до» і «після». Плакати з Гітлером, які спочатку чіпляються, а потім зриваються, можуть слугувати найяскравішим (і водночас метонімічним) прикладом у «Бабин Яр. Контекст». Інший – захоплення Києва Вермахтом, а потім Червоною Армією. Фільм Лозниці по суті складається з двох половин приблизно по одній годині кожна, відносно яких події у Бабиному Ярі знаходяться в середині, є центром. Але наративно цей центр є майже порожнім. Масове вбивство, контекстом якого є хронологія Лозниці, є одночасно перипетією його монтажу та порожнечею в ньому. Автор розглядає спробу Лозниці в аспектах архівології та наратології.
A percepção da importância da inserção da odontologia hospitalar na grade curricular do curso de odontologia: um relato de experiência
Authors: Martins Gabryelle Ferreira , Santos Marília Jaci Azevedo de Oliveira , Vanzo Ketlin Lara Tosta , Pereira Yamba Carla Lara 
Published: May 2023

Objetivo: A higiene bucal efetiva de pacientes internados em Unidades de Terapia Intensiva (UTI) são primordiais, visto que o biofilme bucal tem uma proliferação rápida e é comum a redução da higienização natural da cavidade bucal. Metodologia: Sendo assim, a instituição privada de ensino superior ofertou aos acadêmicos do 9º período de Odontologia a Disciplina de Odontologia hospitalar, disciplina essa que tem como objetivo aumentar o conhecimento dos alunos sobre a importância de um atendimento integral ao paciente em vulnerabilidade. Foram ofertadas 40 vagas aos acadêmicos, na qual as atividades iniciaram em setembro de 2022 e realizadas nas terças feira. Os alunos foram divididos em grupos acompanhados de uma profissional responsável. As práticas foram executadas em Hospitais privados que atendem a capital do estado de Tocantins. Resultados: Evidenciou-se que é de suma importância a higiene oral em todos os pacientes internados em leito hospitalar, pois eles estão muito susceptíveis às doenças externas, sendo a doença periodontal a mazela infecciosa de origem bucal mais prevalente e que pode causar grandes problemas para a saúde do indivíduo. Conclusão: Diante tudo que foi exposto ainda há uma certa resistência quanto a sua integração na equipe multiprofissional, tornando isso um grande desafio.
A COST-EFFECTIVENESS COMPARISON OF THE OPEN AND LAPAROSCOPIC APPENDECTOMIES FOR PEDIATRIC PATIENTS
Authors: BHADAURİA Amita , BHATNAGAR Amogh 
Published: May 2023

Objectives: Laparoscopic appendectomy (LA) is preferred to open appendectomy (OA), as it is less invasive. However, it is debatable whether LA is more cost-effective. We compared the cost-benefits of LA with OA, using the entire pediatric inpatient hospital data in USA.Methods: The Kids' Inpatient Database (KID) shows that 51,007 pediatric patients were subjected to laparoscopic appendectomy and 12,668 to open appendectomy during 2010-12 across the USA. This dataset was used to assess the cost-effectiveness of LA and OA, while controlling for the demographic characteristics of patients (e.g. age and gender), their background (e.g., place of residence), and complexity of surgery (e.g., number of procedures). Results: We found that patients with laparoscopic surgery saved ~0.46 days of hospital stay, but paid $3641 more compared to patients with open surgery. Conclusions: Surgeons prefer to use the technologically advanced laparoscopic appendectomy (80% of patients). Our analysis shows that the cost-benefit of laparoscopic appendectomy is marginal. Hence, for making a fully informed decision, patients should be provided with both clinical and cost comparison data.
EVALUATION OF BED UTILIZATION PERFORMANCE OF HOSPITAL DEPARTMENTS IN TURKEY WITH GREY RELATED ANALYSIS
Authors: YİĞİT Arzu 
Published: May 2023

The aim of this study was to analyze the bed utilization performance of hospital departments in Turkey with grey relational method. Grey relational analysis was used to determine the bed utılization performance levels of surgery and internal clinics in Turkey. In this study, hospital performance indicators are used as variables; bed occupancy rate, bed turnover rate and average length of stay. Research data were obtained from the Statistical Report of Public Hospitals Unions. Data were analyzed using MS Excel, SPSS 18 software. In this study, bed occupancy rate (%), average length of stay (day) and bed turnover rate performance indicators of clinics were found to be 67.3; 5.6 and 63.4, respectively. According to the grey relational analysis, the section with the most desirable characteristics represents the sections with the highest scores. The highest grey relational grade score was found to be obstetrics and gynecology (0.904) and the lowest score dermatology (0.474) departments. In multidimensional analysis, it was evaluated in two categories as efficient and inefficient in evaluating the bed use performance of departments. Hospitals are the most resource-consuming element of a health care system. The hospital's bed utilization performance has a positive impact on the hospital's financial success. A significant portion of the cost of operating in hospitals is due to unnecessary patient hospitalization. In order to reduce hospital costs, patient beds need to be used optimally. Hence, hospital managers should regularly audit bed utilization.
MEMOTRET PENERAPAN AKUNTANSI AKAD MUDHARABAH BERDASARKAN PSAK SYARIAH NOMOR 105 PADA KOPERASI SIMPAN PINJAM SYARIAH
Authors: Diah Nurdiwaty  , Hestin Sri Widiawati  
Published: May 2023

Aktivitas keuangan syariah di Indonesia semakin berkembang pesat, hal ini dibuktikan dengan banyaknya lembaga keuangan yang berbasis syariah. Dalam prakteknya masih banyak masyarakat yang belum memahami kesesuaian aturan yang digunakan dengan praktek yang diterapkan. Salah satu produk pembiayaan produktif yang terdapat pada lembaga keuangan syariah adalah mudharabah. PSAK yang digunakan adalah PSAK No. 105. Peneliti mengambil lokasi penelitian di KSPS BMT UGT Sidogiri cabang Jombang. Permasalahan dalam penelitian ini adalah bagaimana kesesuaian penerapan akad mudharabah di KSPS BMT UGT Sidogiri Cabang Jombang dengan PSAK 105. Adapun pendekatan kualitatif dengan metode deskriptif yang digunakan dalam penelitian ini. Data primer diperoleh dengan wawancara, observasi, dan dokumentasi. Hasil penelitian ini menunjukkan penerapan akuntansi akad mudharabah pada tahun 2018 pada KSPS BMT UGT Sidogiri Cabang Jombang telah sesuai dengan SOP yang ada di KSPS BMT UGT Sidogiri. Untuk pengakuan, pengukuran, pengungkapan dan bagi hasil telah sesuai dengan PSAK No. 105 tetapi dalam penyajiannya masih belum ada kesesuaian.
ANALISIS METODE FULL COSTING DALAM PENETAPAN HARGA JUAL PRODUK (STUDI UKM JAMUR CRISPY FCK)
Authors: Auliya Dewi Oktari  , Dion Yanuarmawan  
Published: May 2023

Metode full costing merupakan metode penentuan harga pokok produksi yang menghitung semua unsur biaya bahan baku, biaya tenaga kerja langsung dan biaya overhead baik yang berperilaku variabel maupun tetap, di mana biaya-biaya tersebut untuk menghitung harga pokok produksi dan harga pokok produksi itulah yang menjadi penentu harga jual produk suatu perusahaan. Harga pokok produksi menurut metode full costing merupakan alat untuk menentukan harga jual yang berdasar pada mark up suatu perusahaan. Penentuan harga jual produk menurut metode full costing dapat menggambarkan harga yang dapat dinilai wajar oleh para konsumen, sehingga dapat memperkirakan keuntungan yang didapat oleh suatu perusahaan. Metode full costing dalam biaya overhead pabrik baik yang berperilaku tetap maupun variabel akan dibebankan kepada produk yang diproduksi atas dasar tarif yang telah ditentukan pada kapasitas normal atau atas dasar overhead pabrik sesungguhnya.
Penetapan harga jual produk merupakan cerminan kualitas produk yang siap untuk dipasarkan secara besar-besaran dan mengharapakan keuntungan yang besar pula. Harga jual produk menjadi hal yang sangat sensitif untuk kelangsungan hidup suatu perusahaan. Harga jual produk yang bagus akan mempengaruhi minat para konsumen, dimana minat tersebut akan menjadi sebuah keuntungan besar bagi suatu perusahaan , jika suatu perusahaan asal dalam menentukan harga jual, maka akan meningkatkan resiko kerugian yang besar pula. Perhitungan metode full costing dalam penetapan harga jual produk adalah salah satu cara perusahan dalam menetapkan harga jual produk yang terbilang wajar dan sesaui dengan ekonomi masyarakat.
Sistem Informasi Pengelolaan Data Kos Annisa Menggunakan Framework Code Igniter 4
Authors: Fitri Zuyina Nur Azizah  , Adine Pramesti Gitaswari  , Dwiana Maryamas Sofa  , Rexana Widyadhana Agusta  , Zulva Nur Fadila  
Published: May 2023

Kos putri Anisa adalah Kos yang terletak di daerah Mojoroto, Kota Kediri dengan fasilitas yang lumayan lengkap dan letaknya strategis. Permasalahan yang sering terjadi adalah penjaga kos kesulitan untuk penambahan data penghuni kos baru dan pengelolaan pembayaran. Hal ini disebabkan keterbatasan informasi yang diperoleh dari masyarakat secara langsung, apalagi mengharuskan si penyewa mencari hunian yang dekat dengan tempat kerja, sekolah atau kampus tempat mereka melaksanakan aktifitas sehari-hari. Sangat banyak sekali permasalahan yang dirasakan saat harus mencari sendiri tempat tinggal yang sesuai dengan selera, baik dilihat dari sisi waktu yang dihabiskan, tenaga, pikiran dan materi yang terkuras mencari hunian yang akan ditempati. Dari segi yang dialami oleh pemilik/penjaga kos itu mereka kesulitan mengelola data penghuni kos karena menggunakan cara manual dengan face to face atau melalui chat, selain itu jika masih menggunakan cara manual, tagihan pembayaran per bulan juga akan menyulitkan penjaga kos karena harus menagih satu per satu.
Oleh karena itu, berdasarkan permasalahan diatas pemanfaatan sistem dan teknolgi informasi secara digital dirasakan mampu memberikan solusi terhadap permasalahan tersebut khususnya di lingkup Kos Putri Anisa. Maka dari itu pengembangan aplikasi berbasis web dalam pengelolaan kos sangat berguna untuk membantu memudahkan dari sisi admin (Pemilik/Penjaga Kos) dan orang yang ingin mencari kos serta sebagai ajang promosi tempat kos agar lebih dikenal banyak orang.
Polycrystal Li2ZnTi3O8/C anode with lotus seedpod structure for high-performance lithium storage
Authors: Chen Zhanjun , Wang Tao , Liu Meihuang , Duan Panyu , Xiong Feng , Zhou Yang , Yan Zhenyu , Yang Wei , Chen Han , Yang Zhenyu , Li Chao 
Published: May 2023

Lotus-seedpod structured Li2ZnTi3O8/C (P-LZTO) microspheres obtained by the molten salt method are reported for the first time. The received phase-pure Li2ZnTi3O8 nanoparticles are inserted into the carbon matrix homogeneously to form a Lotus-seedpod structure, as confirmed by the morphological and structural measurements. As the anode for lithium-ion batteries, the P-LZTO material demonstrates excellent electrochemical performance with a high rate capacity of 193.2 mAh g-1 at 5 A g-1 and long-term cyclic stability up to 300 cycles at 1 A g-1. After even 300 cyclings, the P-LZTO particles can maintain their morphological and structural integrity. The superior electrochemical performances have arisen from the unique structure where the polycrystalline structure is beneficial for shorting the lithium-ion diffusion path, while the well-encapsulated carbon matrix can not only enhance the electronic conductivity of the composite but also alleviate the stress anisotropy during lithiation/delithiation process, leading to well-preserved particles.
Analysis of aptamer-target binding and molecular mechanisms by thermofluorimetric analysis and molecular dynamics simulation
Authors: Zhang Hong-Li , Lv Cong , Li Zi-Hua , Jiang Song , Cai Dan , Liu Shao-Song , Wang Ting , Zhang Kun-He 
Published: May 2023

Introduction: Aptamers are valuable for bioassays, but aptamer-target binding is susceptible to reaction conditions. In this study, we combined thermofluorimetric analysis (TFA) and molecular dynamics (MD) simulations to optimize aptamer-target binding, explore underlying mechanisms and select preferred aptamer.Methods: Alpha-fetoprotein (AFP) aptamer AP273 (as the model) was incubated with AFP under various experimental conditions, and melting curves were measured in a real-time PCR system to select the optimal binding conditions. The intermolecular interactions of AP273-AFP were analysed by MD simulations with these conditions to reveal the underlying mechanisms. A comparative study between AP273 and control aptamer AP-L3-4 was performed to validate the value of combined TFA and MD simulation in selecting preferred aptamers.Results: The optimal aptamer concentration and buffer system were easily determined from the dF/dT peak characteristics and the melting temperature (Tm) values on the melting curves of related TFA experiments, respectively. A high Tm value was found in TFA experiments performed in buffer systems with low metal ion strength. The molecular docking and MD simulation analyses revealed the underlying mechanisms of the TFA results, i.e., the binding force and stability of AP273 to AFP were affected by the number of binding sites, frequency and distance of hydrogen bonds, and binding free energies; these factors varied in different buffer and metal ion conditions. The comparative study showed that AP273 was superior to the homologous aptamer AP-L3-4.Conclusion: Combining TFA and MD simulation is efficient for optimizing the reaction conditions, exploring underlying mechanisms, and selecting aptamers in aptamer-target bioassays.
Bacterial pathogens in pediatric appendicitis: a comprehensive retrospective study
Authors: Felber Julia , Gross Benedikt , Rahrisch Arend , Waltersbacher Eric , Trips Evelyn , Schröttner Percy , Fitze Guido , Schultz Jurek 
Published: May 2023

BackgroundAppendicitis is a frequent condition, with peak incidences in the second decade of life. Its pathogenesis is under debate, but bacterial infections are crucial, and antibiotic treatment remains essential. Rare bacteria are accused of causing complications, and various calculated antibiotics are propagated, yet there is no comprehensive microbiological analysis of pediatric appendicitis. Here we review different pre-analytic pathways, identify rare and common bacterial pathogens and their antibiotic resistances, correlate clinical courses, and evaluate standard calculated antibiotics in a large pediatric cohort.MethodWe reviewed 579 patient records and microbiological results of intraoperative swabs in standard Amies agar media or fluid samples after appendectomies for appendicitis between May 2011 and April 2019. Bacteria were cultured and identified via VITEK 2 or MALDI-TOF MS. Minimal inhibitory concentrations were reevaluated according to EUCAST 2022. Results were correlated to clinical courses.ResultsOf 579 analyzed patients, in 372 patients we got 1330 bacterial growths with resistograms. 1259 times, bacteria could be identified to species level. 102 different bacteria could be cultivated. 49% of catarrhal and 52% of phlegmonous appendices resulted in bacterial growth. In gangrenous appendicitis, only 38% remained sterile, while this number reduced to 4% after perforation. Many fluid samples remained sterile even when unsterile swabs had been taken simultaneously. 40 common enteral genera were responsible for 76.5% of bacterial identifications in 96.8% of patients. However, 69 rare bacteria were found in 187 patients without specifically elevated risk for complications.ConclusionAmies agar gel swabs performed superior to fluid samples and should be a standard in appendectomies. Even catarrhal appendices were only sterile in 51%, which is interesting in view of a possible viral cause. According to our resistograms, the best in vitro antibiotic was imipenem with 88.4% susceptible strains, followed by piperacillin-tazobactam, cefuroxime with metronidazole, and ampicillin-sulbactam to which only 21.6% of bacteria were susceptible. Bacterial growths and higher resistances correlate to an elevated risk of complications. Rare bacteria are found in many patients, but there is no specific consequence regarding antibiotic susceptibility, clinical course, or complications. Prospective, comprehensive studies are needed to further elicit pediatric appendicitis microbiology and antibiotic treatment.
Understanding clinical characteristics influencing adverse outcomes of Omicron infection: a retrospective study with propensity score matching from a Fangcang hospital
Authors: Geng Yanxia , Nie Qingfang , Liu Feifei , Pei Yinghao , Chen Qiuhua , Zhang Haidong , Zhou Haiqi , Zhou Jiang , Jiang Hua , Xu Jing 
Published: May 2023

ObjectivesThe epidemic of coronavirus disease 2019 (COVID-19) is causing global health concerns. The aim of this study was to evaluate influence of clinical characteristics on outcomes during the Omicron outbreak.MethodsA total of 25182 hospitalized patients were enrolled, including 39 severe patients and 25143 non-severe patients. Propensity score matching (PSM) was applied to balance the baseline characteristics. Logistic regression analysis was used to assess the risk of severe disease, as well as the risk of prolonged viral shedding time (VST) and increased length of hospital stay (LOS).ResultsBefore PSM, patients in the severe group were older, had higher symptom scores, and had a higher proportion of comorbidities (p&lt;0.001). After PSM, there were no significant differences in age, gender, symptom score and comorbidities between severe (n=39) and non-severe (n=156) patients. Symptoms of fever (OR=6.358, 95%CI 1.748-23.119, p=0.005) and diarrhea (OR=6.523, 95%CI 1.061-40.110, p=0.043) were independent risk factors for development of severe disease. In non-severe patients, higher symptom score was associated with prolonged VST (OR=1.056, 95% CI 1.000-1.115, p=0.049) and LOS (OR=1.128, 95% CI 1.039-1.225, p=0.004); older age was associated with longer LOS (OR=1.045, 95% CI 1.007-1.084, p=0.020).ConclusionThe overall condition of the Shanghai Omicron epidemic was relatively mild. Potential risk factors for fever, diarrhea, and higher symptom score can help clinicians to predict clinical outcomes in COVID‐19 patients.
Evaluating machine-generated explanations: a “Scorecard” method for XAI measurement science
Authors: Hoffman Robert R. , Jalaeian Mohammadreza , Tate Connor , Klein Gary , Mueller Shane T. 
Published: May 2023

IntroductionMany Explainable AI (XAI) systems provide explanations that are just clues or hints about the computational models-Such things as feature lists, decision trees, or saliency images. However, a user might want answers to deeper questions such as How does it work?, Why did it do that instead of something else? What things can it get wrong? How might XAI system developers evaluate existing XAI systems with regard to the depth of support they provide for the user's sensemaking? How might XAI system developers shape new XAI systems so as to support the user's sensemaking? What might be a useful conceptual terminology to assist developers in approaching this challenge?MethodBased on cognitive theory, a scale was developed reflecting depth of explanation, that is, the degree to which explanations support the user's sensemaking. The seven levels of this scale form the Explanation Scorecard.Results and discussionThe Scorecard was utilized in an analysis of recent literature, showing that many systems still present low-level explanations. The Scorecard can be used by developers to conceptualize how they might extend their machine-generated explanations to support the user in developing a mental model that instills appropriate trust and reliance. The article concludes with recommendations for how XAI systems can be improved with regard to the cognitive considerations, and recommendations regarding the manner in which results on the evaluation of XAI systems are reported.