bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dipole doping effect in MoS2 field effect transistors based on phase transition of ferroelectric polymer dopant
Authors: Lee Dong Hyun , Park Taehyun , Jeong Taeho , Jung Youngkyun , Park Junghee , Joo Nackyong , Won Uiyeon , Yoo Hocheon 
Published: April 2023

Molybdenum disulfide (MoS2) has great potential for next-generation electronic devices. On the other hand, stable doping methods are required to adjust its physical properties so MoS2 can be utilized in practical applications, such as transistors and photodetectors. On the other hand, a conventional doping method based on ion implantation is incompatible with 2D MoS2 because of the damage to the lattice structures of MoS2. This paper presents an n-type doping method for MoS2 field-effect transistors (FETs) using a poly (vinylidene fluoride-co-trifluoroethylene) (P (VDF-TrFE)) and polar polymer. The dipole moment of P (VDF-TrFE) provides n-type doping on MoS2 FETs. The polar phase formation in dopant films enhances the doping effects, and the relationship between phase transition and n-type doping states was investigated using optical and electrical characterization methods. Under the optimal doping conditions, the doped MoS2 FET achieved an improved field effect mobility of 34.4 cm2 V−1s–1, a negative shift in the threshold voltage by −25.6 V, and a high on-current of 21 μA compared to the pristine MoS2 FET.
High intact fibroblast growth factor 23 levels associated with low hemoglobin levels in patients on chronic hemodialysis
Authors: Fang Yu-Wei , Wang Jing-Tong , Lin Tzu Yun , Lee Chung-Jen , Jang Tsrang-Neng , Tsai Ming-Hsien , Liou Hung-Hsiang 
Published: April 2023

IntroductionA negative association between C-terminal fibroblast growth factor 23 (cFGF23) and hemoglobin (Hb) levels has been reported in patients with predialysis chronic kidney disease. In dialysis patients, the dominant form of serum FGF23 is intact FGF23 (iFGF23); however, its association with the Hb level remains unclear. Therefore, simultaneously monitoring iFGF23 and cFGF23 levels is crucial. In this study, we investigated the associations between both forms of FGF23 (iFGF23 and cFGF23) and renal anemia in chronic hemodialysis (CHD) patients.MethodsWe included 166 CHD patients from two hospitals in this cross-sectional, observational study. The primary predictors were serum iFGF23, cFGF23, and iFGF23/cFGF23 levels. The main outcome was the Hb level.ResultsAmong the CHD patients included, 60.8% were men with a mean age of 59.4 ± 12.7 years. In the crude analysis, iFGF23 and iFGF23/cFGF23 levels showed a significant negative association (−0.27, p = 0.004 and −0.22, p = 0.034, respectively) with the Hb level. Even after adjusting for multiple variables (a parsimonious model), every increment of natural log transformation by 1 for (ln)iFGF23 and ln(iFGF23/cFGF23) levels showed a negative correlation with the Hb level (estimate: −0.27 [95%CI: −0.44, −0.10, p = 0.001]; −0.19 [95%CI: −0.37, −0.01, p = 0.042], respectively), whereas both were positively associated with erythropoietin-stimulating agent (ESA) hyporesponsiveness (odds ratio [OR]: [95%CI: 2.30, 1.26–4.17], p = 0.006; 1.95 [95%CI: 1.08–3.50], p = 0.025). Moreover, these abovementioned associations were more dominant in patients with diabetes who used angiotensin receptor blockers.DiscussionIn conclusion, a negative association between serum iFGF23 or iFGF23/cFGF23 level and the Hb level was observed in our CHD patients. Meanwhile, a higher iFGF23 or iFGF23/cFGF23 level may predispose patients to ESA hyporesponsiveness.
Brain metastases in the elderly – Impact of residual tumor volume on overall survival
Authors: Baumgart Lea , Aftahy Amir Kaywan , Anetsberger Aida , Thunstedt Dennis , Wiestler Benedikt , Bernhardt Denise , Combs Stephanie E. , Meyer Bernhard , Meyer Hanno S. , Gempt Jens 
Published: April 2023

BackgroundDue to demographic changes and an increased incidence of cancer with age, the number of patients with brain metastases (BMs) constantly increases, especially among the elderly. Novel systemic therapies, such as immunotherapy, have led to improved survival in recent years, but intracranial tumor progression may occur independently of a systemically effective therapy. Despite the growing number of geriatric patients, they are often overlooked in clinical trials, and there is no consensus on the impact of BM resection on survival.ObjectivesThe aim of this study was to analyze the impact of resection and residual tumor volume on clinical outcome and overall survival (OS) in elderly patients suffering from BM.MethodsPatients ≥ 75 years who had surgery for BM between April 2007 and January 2020 were retrospectively included. Residual tumor burden (RTB) was determined by segmentation of early postoperative brain MRI (72 h). Contrast-enhancing tumor subvolumes were segmented manually. “Postoperative tumor volume” refers to the targeted BMs. Impact of preoperative Karnofsky performance status scale (KPSS), age, sex and RTB on OS was analyzed. Survival analyses were performed using Kaplan-Meier estimates for the univariate analysis and the Cox regression proportional hazards model for the multivariate analysis.ResultsOne hundred and one patients were included. Median age at surgery was 78 years (IQR 76-81). Sixty-two patients (61%) had a single BM; 16 patients (16%) had two BMs; 13 patients (13%) had three BMs; and 10 patients (10%) had more than three BMs. Median preoperative tumor burden was 10.3 cm3 (IQR 5–25 cm3), and postoperative tumor burden was 0 cm3 (IQR 0–1.1 cm3). Complete cytoreduction (RTB = 0) was achieved in 52 patients (52%). Complete resection of the targeted metastases was achieved in 78 patients (78%). Median OS was 7 months (IQR 2–11). In univariate analysis, high preoperative KPSS (HR 0.986, 95% CI 0.973–0.998, p = 0.026) and small postoperative tumor burden (HR 1.025, 95% CI 1.002–1.047, p = 0.029) were significantly associated with prolonged OS. Patients with RTB = 0 survived significantly longer than those with residual tumor did (12 [IQR 5–19] vs. 5 [IQR 3–7] months, p = 0.007). Furthermore, prolongation of survival was significantly associated with surgery in patients with favorable KPSS, with an adjusted HR of 0.986 (p = 0.026). However, there were no significances regarding age.ConclusionsRTB is a strong predictor for prolonged OS, regardless of age or cancer type. Postoperative MRI should confirm the extent of resection, as intraoperative estimates do not warrant a complete resection. It is crucial to aim for maximal cytoreduction to achieve the best long-term outcomes for these patients, despite the fact the patients are advanced in age.
Appropriateness of frequent use of emergency departments: A retrospective analysis in Rome, Italy
Authors: Furia Giuseppe , Vinci Antonio , Colamesta Vittoria , Papini Paolo , Grossi Adriano , Cammalleri Vittoria , Chierchini Patrizia , Maurici Massimo , Damiani Gianfranco , De Vito Corrado 
Published: April 2023

BackgroundFrequent users (FUs) are patients who repeatedly and inappropriately visit the emergency department (ED) for low-grade symptoms that could be treated outside the hospital setting. This study aimed to investigate the phenomenon of the FU in Rome by profiling such users and analyzing ED attendance by FUs.MethodsThe analysis was carried out for attendance in 2021 at 15 EDs in the Local Health Authority Roma 1 geographical area. A digital app collected data, including information on the following variables: number of attendance, demographic characteristics, emergency medical service (EMS) usage, triage code, and appropriateness of attendance. COVID-19 diagnosis was also studied to analyze any possible influence on ED attendance. Differences between FUs and non-FUs were investigated statistically by t-test and chi-square test. Univariate analysis and multivariable logistic regression were performed to analyze the associated factors.ResultsA total of 122,762 ED attendance and 89,036 users were registered. The FU category represented 2.9% of all users, comprising 11.9% of total ED attendance. There was a three times higher frequency of non-urgent codes in attendance of FU patients (FU: 9.7%; non-FU: 3.2%). FUs were slightly more likely to have used the EMS (13.6% vs. 11.4%) and had a lower frequency of appropriate ED attendance (23.8% vs. 27.0%). Multivariate logistic analysis confirmed a significant effect of triage code, gender, age, EMS usage, and COVID-19 diagnosis for the appropriateness of attendance. The results were statistically significant (p &lt; 0.001).ConclusionThe FU profile describes mostly non-urgent and inappropriate attendance at the ED, including during the COVID-19 pandemic. This study represents an important tool for strengthening preventive policies outside the hospital setting. The Italian National Recovery and Resilience Plan represents an excellent opportunity for the development of new strategies to mitigate the phenomenon of FUs.
Foro Mundial sobre la Educación. Marco de Acción Regional. «Educación para todos en las Américas»
Authors: - - 
Published: April 2023

Diez años después de la «Conferencia Mundial de Educación para Todos» (Jomtien, 1990), los países de América Latina, El Caribe y América del Norte, evaluaron los progresos realizados en la Región hacia el logro de los objetivos y metas entonces formulados. Reunidos en Santo Domingo del 10 al 12 de febrero del 2000, los países renuevan en el presente Marco de Acción Regional sus compromisos de Educación Para Todos para los próximos quince años.
ASEPSIS BETWEEN THE DENTAL OFFICE AND LABORATORY: A TUNISIAN CROSS-SECTIONAL STUDY
Authors: Oumaima Tayari , Hela Haloui , Safa Jemli , Jamila Jaouadi 
Published: April 2023

Introduction: For a long time, the prevention of cross-contamination in dentistry has mainly been concentrated in the operating room. Activity related to laboratory work, a potential source of pathogen transmission, is therefore often overlooked. In addition, the practice of prosthodontics often gives the impression that aseptic measures cannot be rigorously applied. Several factors account for this situation. Designing a prosthesis involves handling a certain number of potentially contaminated and heat-sensitive objects (prostheses, impressions, wax tubes, occlusion bites, etc.). The items transferred between the dental office and the dental laboratory as well as the prosthetic instruments constitute the main chain of cross contamination in prosthodontics. Thus, an evaluation of the dentists and prosthetists’ compliance with regard to their asepsis through a cross-sectional study was necessary. Methods: two anonymous questionnaires were distributed. The first was among the dentists and the second to dental prosthetists in the public and private sectors. Results: From the 302 questionnaires distributed, only 220 were filled-in. 78% of the dentists and 37% of the prosthetists know the disinfection protocol of reusable instrumentation. 80.3% of the dentists and 74.1% of the prosthetists disinfect their prosthetic work but with varying percentages according to the group of items (impressions, prosthesis, etc.). 71.5% of the practitioners and 18.5% of the technicians disinfect their laboratory instruments systematically. However, 45% of the dentists and 54% of the prosthetists think they are not exposed to infections. Discussion: The results showed an insufficient level of knowledge and compliance to ensure asepsis of the prosthetic work both in the public and private sectors, contributing to a relatively high level of exposure to infections compared to a Canadian study. Conclusion: Given the insufficient compliance and in order to remedy these deficiencies, a simple decontamination protocol is suggested. Improving awareness and providing continuous training are then required.
‘Cantare alla greca con citere e violini’: Western Musical Transfers and Localisations in Early Modern Crete
Authors: Hatzikiriakos Alexandros Maria 
Published: April 2023

During the late mediaeval and early modern periods, Crete was the most important Venetian colony, giving the Republic almost unchallenged commercial and military control of the eastern Mediterranean. Based on archive and documentary evidence, this article discusses the role played by music as a means of social and cultural control over the native Cretan population.
After a brief introduction to the history of the Venetian domination of Crete (aka Venetocracy) and of its impact on local literature and visual arts, the first section deals with the presence of Western music in the Venetian secular and religious institutions. From a very early stage, Venice started employing locals as civic musicians (mostly trumpeters and ‘piffari’). For the locals themselves, a stable role in the local musical institution represented an opportunity for income and social ascension; for the Republic, meanwhile, it was a means of political and cultural control. Music was also central to religious institutions, as documented by archive sources. The main churches and monasteries on the island had instruments and singers and provided training for the Catholic clergy and musicians.
The article goes on to explore the dissemination of Western secular instrumental and polyphonic practices in the main Cretan cities, taking as a case study literary sources dating from the fifteenth and sixteenth centuries which testify to polyphonic compositions in Greek, such as madrigals and incidental music. A last example is represented by the chivalric romance Erotokritos, containing references to Western musical symbolism, such as the myth of Orpheus as a good rhetor and sovereign, and the lute representing civic harmony. Written by a Hellenised Venetian nobleman, Erotokritos represents the most manifest case of musical values being used for pro-Venetian propaganda.
القيادة التحويلية وعلاقتها بالأبداع في الأداء الوظيفي من وجهة نظر موظفي وزارة الشباب والرياضة في العراق
Authors: صبحي احمد أنمار , محمد عبدالخالق أحمد 
Published: April 2023

هدف البحث الى بيان مدى تأثير القيادة التحويلية على مستوى الابداع في الأداء الوظيفي في دائرة شؤون الأقاليم والمحافظات في وزارة الشباب والرياضة، اذ قام الباحثان ببناء مقياسي احدهما للقيادة التحويلية واخر للإبداع في الأداء الوظيفي، ولتحقيق الاهداف اعتماد الباحثان المنهج الوصفي بالطريقة المسحية على عينة البحث التي تم اختيارها بالطريقة العمدية لملائمتها مع اهداف البحث والتي شملت (300) موظفاً في دائرة الأقاليم والمحافظات في وزارة الشباب والرياضة، ليتم بعدها بناء واعداد مقياسي للقيادة التحويلية و للإبداع في الأداء الوظيفي من خلال توزيع استبانات على الخبراء واختيار المجالات والفقرات الأنسب للمقياس، واجراء الاسس الخاصة في بناء وتعديل المقاييس من صدق وثبات وموضوعية وبعد توزيعها على افراد عينة البحث وجمعها واجراء العمليات الاحصائية وإخراج العلاقات الارتباطية ومن ثم تحليل النتائج التي حصل عليها الباحثان في الحقيبة الإحصائية للتعرف على العلاقة بين المتغيرات المراد دراستها من قبل الباحثان، حيث أظهرت النتائج ان هنالك علاقة طردية بين المتغيرين وان هنالك تأثير معنوي للقيادة التحويلية على الابداع في الأداء الوظيفي، وأوصى الباحثان الاعتماد على القيادة التحويلية بشكل اكبر في إدارة شؤون الدائرة وباقي دوائر الوزارة.
تأثير تمرينات بأسلوب تبادل المراكز وفق المسافات المقطوعة في تطوير القوة المميزة بالسرعة وعلاقتها بالتهديف للاعبي كرة القدم الشباب
Authors: هاشم محمد , ناجي ضياء 
Published: April 2023

هدف البحث الى استخدام تمرينات بأسلوب تبادل المراكز وفق المسافات المقطوعة ومعرفة تأثيرها في تطوير القوة المميزة بالسرعة وعلاقتها بالتهديف للاعبي كرة القدم الشباب. واستخدم الباحثان المنهج التجريبي وفق تصميم المجموعة الواحدة ذو الاختبارين القبلي والبعدي، وتم اختيار مجتمع البحث بالطريقة العمدية والبالغ عددهم (18) لاعباً من لاعبي نادي الصناعة بكرة القدم الشباب وبنسبة (83.3 %) من مجتمع البحث. وتم تنفيذ التمرينات المعدة في القسم الرئيسي من الوحدات التدريبية، واستنتج الباحثان ان التمرينات بأسلوب تبادل المراكز وفق المسافات المقطوعة تعمل على تطوير القوة المميزة بالسرعة للاعبي كرة القدم الشباب، وان هذه التمرينات تعمل على تطوير مهارة التهديف للاعبي كرة القدم الشباب، وأوصى الباحثان بالتأكيد على استخدام التمرينات بأسلوب تبادل المراكز وفق المسافات المقطوعة لتطوير القوة المميزة بالسرعة ، إجراء بحوث ودراسات على استخدام التمرينات بأسلوب تبادل المراكز على لعبة كرة القدم للساحات المكشوفة لمختلف الفئات العمرية والصالات.
Capabilities of auxiliary techniques for low strain impact testing of piles foundations
Authors: Churkin A. A. 
Published: April 2023

Introduction. An increase in the complexity of tasks arising from the quality control of geotechnical structures ultimately increases the role of indirect methods as part of the survey set. Low strain impact testing of piles length and integrity is currently one of the most common non-destructive geophysical methods used in the state diagnostics of foundations. The capabilities and limitations of the method are associated with the peculiarities of its basic theoretical model describing the propagation of elastic waves in a thin rod. In this regard, specialists often have recourse to the auxiliary techniques of field research.Aim. To inform test engineers, designers and employees of supervisory organizations about the potential of auxiliary methods for the low strain impact quality control of pile foundations.Methods and materials. The features of the theoretical model of the low strain impact pile quality control, as well as the associated capabilities and limitations of the method are described. The auxiliary methods of data collection and analysis were used for the survey of pile foundations, including those in the composition of existing structures.Results. The results of the work are represented by additional information obtained about the foundations surveyed using the auxiliary methods of data collection and analysis. An alternative arrangement of sensors relative to the surveyed structure was used for determining the depth of piles in the composition of grade beam footings and existing structures. The common shot point profiling (ultra-seismic method) was used to assess the velocity of rod wave propagation in the body of the structure. The options of data presentation in the parallel seismic method were used to demonstrate its potential for the quality control of foundation concrete.Conclusion. The auxiliary methods of data collection and analysis used in the low strain impact survey of pile foundations can significantly increase the reliability of conclusions about the depth and integrity of a structural material.
On the issue of determining the dimensions of the rock massif cavity sufficient for the formation of a sinkhole in the overlying soil stratum
Authors: Sheinin V. I. , Kovalev V. A. , Patrikeev A. B. , Kholmyanskiy M. L. 
Published: April 2023

Introduction. The procedure currently recommended for karst hazard assessment includes a comparison of the cavity dimensions at the top of the karst massif with a “critical” value, sufficient for a shift of the cylindrical volume in the soil stratum. The scheme of calculating the “critical” value, proposed 40 years ago, is widely used due to its proven efficiency. However, in some cases, this procedure leads to an incorrect assessment of sinkhole development conditions, i.e., to incorrect decisions about the parameters of anti-karst measures.Aim. To adjust the procedure for calculating the “critical dimensions”, depending on the stratum structure and soil characteristics, as well as the load from the foundation.Materials and methods. The calculation formulas, transformed for computer calculations, are corrected by the introduction of a variable stability factor, the refinement of the schemes for accounting the effect of a surface load on the forces, acting along the side surface of the “shifting” volume, as well as by accounting, under the fulfillment of conditions for the general stability of a soil cylinder, the possibility of destroying the lower soil bearing layer, which is modeled as the clamped plate, loaded according to two different schemes depending on the properties of overlying soils.Results. The results of comparative calculations performed using the Mathcad software package for “standard” conditions are analyzed, and conclusions about the significance of the proposed corrections are drawn.Conclusion. When determining critical dimensions, it is necessary to introduce the values of the stability coefficient for the “shifting” soil volume, which are standard for geotechnics. In the case of using slab foundations, recommended in “karst-hazardous” areas, the effect of a surface load on the soil shift should be taken into account only when determining horizontal stresses on the side surface. Moreover, accounting can be carried out according to simple, but sufficiently justified, schemes. When the possibility of the lower layer destruction is accounted, the formation of a sinkhole is predicted at a smaller cavity span as compared to the proposed procedures.
PREVENTION BY THE STATE AUTHORITIES OF THE RUSSIAN FEDERATION OF THE IMPORT INTO THE TERRITORY OF THE RUSSIAN FEDERATION AND THE SALE OF COUNTERFEIT, SUBSTANDARD AND UNREGISTERED MEDICINES AND MEDICAL DEVICES
Authors: Суровикина Анна Евгеньевна 
Published: April 2023

Статья посвящена задачам, функциям и обязанностям органов государственной власти по предупреждению преступлений, связанных с ввозом на территорию Российской Федерации и сбытом фальсифицированных, недоброкачественных и незарегистрированных лекарственных средств и медицинских изделий. Предложены новые пути совершенствования мер реагирования на незаконное обращение медицинской продукции.
The article is devoted to the tasks, functions and responsibilities of state authorities to prevent crimes related to the import into the territory of the Russian Federation and the sale of counterfeit, substandard and unregistered medicines and medical devices. New ways of improving the response to the illegal circulation of medical products are proposed.
THE ROLE OF INTERNET MARKETING IN PRODUCT PROMOTION
Authors: Акаева Вероника Роммилевна , Габдулхакова Лейла Ирековна 
Published: April 2023

В статье определена роль Интернет-маркетинга и его инструментов в повышении эффективности бизнеса. Представлены рекомендации по использованию инструментов Интернет-маркетинга в онлайн-торговле.
The article defines the role of Internet marketing and its tools in improving business efficiency. Recommendations on the use of Internet marketing tools in online trading are presented.
STAGES OF DEVELOPMENT OF THE THEORY OF INNOVATION
Authors: Кобин Павел Николаевич 
Published: April 2023

Понятие инновации сегодня прочно вошло в повседневную жизнь. Инновации используются во всех сферах человеческой деятельности, а как экономическая категория они имеют многоуровневый и системный характер. В данной статье изложены основные этапы становления теории инноваций от ее истоков до наших дней.
The concept of innovation is now firmly established in everyday life. Innovations are used in all spheres of human activity, and as an economic category they have a multilevel and systemic character. This article outlines the main stages in the formation of the theory of innovation from its origins to the present day.
THE MAIN ASPECTS OF THE HEALTH-SAVING EDUCATIONAL SPACE OF THE MEDICAL SCHOOL
Authors: Мукаилова Альбина Мукаиловна 
Published: April 2023

В статье на приведен анализ существующих трактовок понятия «здоровье». Представлены признаки педагогической технологии, на основании которых сделан вывод об отсутствии унифицированного подхода в педагогической деятельности организации и проведению учебного процесса в медицинских училищах. Рассмотрены составляющие системы пропаганды здоровьесбережения граждан РФ. Сделаны выводы о необходимости создания условий, обеспечивающих подготовку профессионально компетентного специалиста и духовно, нравственно и физически здоровой личности.
The article does not analyze the existing interpretations of the concept of "health". The features of pedagogical technology are presented, on the basis of which it was concluded that there is no unified approach in the pedagogical activity of the organization and the educational process in medical schools. The components of the system of propaganda of health saving of citizens of the Russian Federation are considered. Conclusions are drawn about the need to create conditions that ensure the training of a professionally competent specialist and a spiritually, morally and physically healthy person.