bluuebunny/crossref_metadata_2025_split huggingface dataset:
‘Sneaky’ uninflamed oesophageal candidiasis: morphological clues and comparison with candidiasis associated with inflammation
Authors: Mirzabeigi Yasamin , Alkhatery Turky , Abulaban Amr , Ruiz Casas Felipe , Montgomery Elizabeth Anne 
Published: January 2025

AimsCandidaesophagitis is usually readily identified on routine H&E-stained sections as the infection typically presents with prominent acute inflammation as a clue to search for organisms. However, in some cases, inflammation is absent, and detection of organisms relies on the observation of zones exhibiting parakeratosis with a delicate ‘flaky’ appearance. Our study aimed to establish a correlation between the histomorphology of oesophageal candidiasis and an associated clinical profile.MethodsWe reviewed 53 sequential biopsy specimens from patients withCandidaesophagitis collected over 1 year. Biopsies were assessed for acute inflammation, intraepithelial lymphocytosis and lymphoid aggregates. Patients’ medical records were reviewed for data on age, gender, race, immune status, smoking, corticosteroid use, HIV status and organ transplantation history. Correlations between these factors and histomorphological patterns were assessed using test.ResultsOf the 53 biopsies, 20 lacked acute inflammation and 33 had it. 15 biopsies showed both acute and lymphoid inflammation and 5 showed lymphocytosis only. Among 16 smokers, 6 (37%) had acute inflammation and 10 (63%) had parakeratosis. In non-smokers, 24 (71%) had acute inflammation and 10 (29%) had parakeratosis. A significant correlation was found between smoking and absence of acute neutrophilic infiltration (p=0.025), but no other clinical factor was associated with inflammatory patterns.ConclusionsCandidaesophagitis can be uninflamed with ‘flaky’ parakeratosis or associated with acute inflammation or lymphocytosis with or without neutrophilic infiltration. Inflammation was often absent in smokers, suggesting synergistic local immunosuppressive effect is this overall immunosuppressed population.
Improving Sequential Recommendations with LLMs
Authors: Boz Artun , Zorgdrager Wouter , Kotti Zoe , Harte Jesse , Louridas Panos , Karakoidas Vassilios , Jannach Dietmar , Fragkoulis Marios 
Published: January 2025

The sequential recommendation problem has attracted considerable research attention in the past few years, leading to the rise of numerous recommendation models. In this work, we explore how Large Language Models (LLMs), which are nowadays introducing disruptive effects in many AI-based applications, can be used to build or improve sequential recommendation approaches. Specifically, we design three orthogonal approaches and hybrids of those to leverage the power of LLMs in different ways. In addition, we investigate the potential of each approach by focusing on its comprising technical aspects and determining an array of alternative choices for each one. We conduct extensive experiments on three datasets and explore a large variety of configurations, including different language models and baseline recommendation models, to obtain a comprehensive picture of the performance of each approach.
Among other observations, we highlight that initializing state-of-the-art sequential recommendation models such as BERT4Rec or SASRec with embeddings obtained from an LLM can lead to substantial performance gains in terms of accuracy. Furthermore, we find that fine-tuning an LLM for recommendation tasks enables it to learn not only the tasks, but also concepts of a domain to some extent. We also show that fine-tuning OpenAI GPT leads to considerably better performance than fine-tuning Google PaLM 2. Overall, our extensive experiments indicate a huge potential value of leveraging LLMs in future recommendation approaches. We publicly share the code and data of our experiments to ensure reproducibility.
Improving Sexual Well‐Being Support for Men With Prostate Cancer: The Health Professional Perspective
Authors: Charlick Megan , Ettridge Kerry , Tiruye Tenaw , O’Callaghan Michael , Sara Sally , Jay Alexander , Beckmann Kerri 
Published: January 2025

Purpose: The provision of evidenced‐based sexual well‐being support is considered a key metric of quality prostate cancer care. However, patients continually report high rates of unmet sexual health needs. To provide insight into the challenges healthcare professionals (HCPs) face in delivering sexual well‐being support, we conducted a qualitative study.Methods: HCPs were recruited via professional organisations/networks and snowballing. Interviews were semistructured, conducted via telephone/video and transcribed verbatim. Interviews explored work experience, sexual support provided, challenges faced and areas of prioritisation to improve care delivery. Data were analysed using reflexive thematic analysis. The lack of representation from urologists and radiation oncologists was a limitation.Results: Twenty‐one HCPs were interviewed, including nurses, pharmacists, sexologists, a physiotherapist and an oncologist. Eight key themes were identified. Themes 1–5 describe the challenges faced by HCPs in providing sexual well‐being support, such as logistical issues and reliance on other HCPs. The remaining three themes describe areas of change recommended by HCPs to improve delivery of support, including standardisation of penile rehabilitation guidelines, training for specialists and GPs and prioritisation of multidisciplinary sexual well‐being support as part of routine care.Conclusions: HCPs face several challenges in providing sexual well‐being support to prostate cancer patients, which could be ameliorated through greater awareness and education about the importance of sexual well‐being support and through standardising pathways and guidelines. Addressing challenges faced by HCPs in the delivery of sexual well‐being support may ultimately improve patient experiences and reduce unmet sexual health needs following prostate cancer treatment.
Positive Governance of Saudi Domain Names
Authors: Alharthi Mashael Helal 
Published: January 2025

Abstract
Most evaluations of the internet in Saudi Arabia focus upon negative (restrictive) aspects of governance that limit the use of the internet, whereas this study focuses upon positive approaches to governance, which enable the fuller use of the internet through positive objectives, by means of developing the logical internet infrastructure. This study is concerned with the Domain Name System (DNS) as an essential element of the logical internet infrastructure layer. Thus, it focuses on the nature of the governance of Saudi domains and the relevant mechanisms in Saudi Arabia. It explains the roles of government and the private sector by assessing their interventions, and it examines to what extent these interventions are effective and fair in encouraging the development of the logical internet infrastructure in Saudi Arabia. It includes data from semi-structured interviews and adopted a policy transfer approach so as to benefit from the UK’s experiences in this field.
Hidden Meaning amidst the Chaos of Life
Authors: Boccassini Daniela 
Published: January 2025

Abstract
This article addresses the presence in Jung’s writings of the archetypes of meaning (‘the wise old man’) and anima (‘life itself’), understood as personalized, yet also timeless, transformative ‘complexes of experience’. In this perspective, Elijah-Philemon, Salomé-anima, Ha, Ka, and Phanēs belong to a kinship that Jung endeavored to retrace to its furthest reaches, the Islamic and Gnostic layers soon giving way to their ancient Egyptian Hermetic roots. By engaging dialogically with these figures, hence by recognizing their transpersonal and transhistorical agency, Jung succeeded in reviving ‘that most ancient’, deeply feminine, form of thinking which understands intelligence as ‘an autonomous activity whose object [mankind] is’ (Jung, 1968a, § 79). The challenge of developing an embodied, feeling-based relationship with the archetypal figures of cosmic psyche remains sound advice today, besieged as we are by increasingly meaning-deprived and life-wanting approaches to ‘intelligence’, construed as an autonomous, hence artificially-reproducible, activity whose subject mankind purports to be.
Organizing vision revisited and reimagined for a changing world
Authors: Swanson E Burton , Ramiller Neil , Wang Ping 
Published: January 2025

Organizing vision (OV) theory, developed more than 25 years ago, posits a broad, diverse, and collective envisioning process at the heart of information technology innovation and diffusion. We revisit the theory and review more than 150 publications that have referenced the original paper, seeking to ascertain how the theory has been found useful in addressing innovation with information technology. We group and analyze these contributions according to how the promotion, reception, and enactment of organizing visions engage participants in bringing about change. In our review, we find that a varied group of some 46 technologies and their OVs have been studied. We consider how these contributions have also drawn from and spoken to related theories, topics, and literatures, finding that the influence of OV theory has largely been confined to the information systems field. Looking to the future, we address: (i) whether newer technologies in the changing digitized world are problematic for OV theory; (ii) how the overall engagement mechanism comprising promotion, reception, and enactment can be more deeply understood; and (iii) how OV theory can speak more effectively beyond traditional IS disciplinary bounds. Building especially on the more recent contributions, we propose a reimagining of the theory with which to guide its continued development and application.
A prospective comparative study of open versus laparoscopic stage II Fowler-Stephens orchidopexy in pediatric patients
Authors: Hamid Raashid , Sudanshu Akshit , Fahiem-Ul-Hassan Mir , Nabi Ubayer , Jan Shah Waseem , Bhat Nisar A , Baba Ajaz A , Mufti Gowhar Nazir , Bashir Idrees , Ahmad Fayaz 
Published: January 2025

Introduction: Laparoscopic Fowler Stephens orchidopexy, single stage or two-stage, is now routinely performed in non-palpable testis. We performed second stage orchidopexy as open inguinal approach and compared the outcome of this approach to two-staged laparoscopic orchidopexy. Methods: We performed a prospective randomized interventional study of two different approaches for intra-abdominal testis. In group A, Laparoscopic stage I (SFO) followed by open inguinal orchidopexy was compared for final outcome in group B cases, who underwent laparoscopic staged SF orchidopexy. The average duration between stage I SF and stage II SF was 6 months. All the procedures were done under GA and caudal analgesia. The pre-operative and post-operative USG dimensions were compared in cm and cm3/ml. The procedure outcome was considered successful if testis remained inside scrotum below mid-scrotal point. Any testis above the mid-scrotal point was considered as unacceptable or failure of procedure. Results: This study was performed on 74 children with 84 testis (group ‘A’ 38 patients (48 testis) and group ‘B’ 36 patients (46 testes)), with average age was 3.3 ± 0.46 and 3.9 ± 0.58 years, respectively. In group ‘A’, 38 patients (48 testes) underwent lap SFO I followed by inguinal orchidopexy and in group ‘B’, 36 patients (46 testes) underwent laparoscopic staged SF O. The mean testicular volume pre-operative in group ‘A’ & ‘B’ was 0.28 ± 0.04 and 0.23 ± 0.06 cm2, respectively. The mean post-operative testicular volume was 0.34 ± 0.07 and 0.28 ± 0.05 cm2, respectively. The average follow-up of the patients in group ‘A’ & ‘B’ was 24 ± 3.67 and 20 ± 2.90 months, respectively. Testis was having good volume in 87.5% and 76.60% of these successful cases, respectively. There were (3/48) 6.25% (4/46) 8.69% testicular atrophy cases in group ‘A’ & ‘B’, respectively. The differences were not statistically significant ( p < 0.05). The mean operative time in group A was 20 ± 8.07 min and group B 30 ± 7.19 min in stage II procedure. Conclusion: The success rate in group A was more than the group B which was statistically significant ( p > 0.05). Our study connotes that open stage II orchidopexy is still feasible and practicable with better final outcome of management of non-palpable cases.
The Mediating Role of Compassion in the Relationship Between Nurses’ Ethnocultural Empathy and Cultural Sensitivity: Structural Equation Model Analysis
Authors: Aydin Er Rahime , Bulut Tuba Yilmaz , Erol Funda 
Published: January 2025

Introduction: Nurses must possess the capacity for compassionate care and exhibit empathy to promote culturally competent care. This research investigated the mediating role of compassion in the relationship between ethnocultural empathy and intercultural sensitivity among nurses. Method: The study was conducted at a hospital that provides health care services to refugees. In total, 125 nurses were recruited through the simple random sampling technique. Data were collected using a personal form and three scales. Statistical analysis was performed using SPSS23 and AMOS24. Results: Nurses’ cultural sensitivity positively influenced their compassion competence and ethnocultural empathy. Compassion competence did not function as a full mediator in the relationship between intercultural sensitivity and ethnocultural empathy. Discussion: This study revealed that exposure to different cultures contributed to compassion competence, ethnocultural empathy, and cultural sensitivity skills in nurses. Cultural competence is a critical component of nursing care; therefore, it should be developed through curriculum revisions and a sensitive and supportive discussion of experiences.
Long-Term Effects of Ozone Treatment in Patients with Persistent Numbness and Tingling Secondary to Chemotherapy-Induced Peripheral Neuropathy. A Retrospective Study
Authors: Clavo Bernardino , Rodríguez-Abreu Delvys , Galván-Ruiz Saray , Federico Mario , Cánovas-Molina Angeles , Ramallo-Fariña Yolanda , Antonilli Carla , Benítez Gretel , Fabelo Himar , García-Lourve Carla , González-Beltrán Damián , Jorge Ignacio J. , Rodríguez-Esparragón Francisco , Callico Gustavo M. 
Published: January 2025

Background: Numbness and tingling secondary to chemotherapy-induced peripheral neuropathy (CIPN) are frequent side effects that limit chemotherapy treatment and quality of life. Successful treatments for CIPN are limited. This preliminary report shows the potential long-term effects of ozone treatment in the management of persistent numbness and tingling secondary to CIPN. Methods: Ozone treatment was administered by rectal insufflation in 15 patients (female/male: 8/7, age: 66 years old) suffering from persistent numbness and tingling secondary to grade-2 or grade-3 CIPN. Planned ozone treatment consisted of 40 sessions over 4 months. The initial concentration of 10 μg/mL was progressively increased to 30 μg/mL. The initial gas volume of 180 mL/session was progressively increased to 300 mL/session if tolerated. Before and after ozone treatment, and at 3- and 6- months after the end of treatment, they were assessed (i) the grade of CIPN-toxicity, and (ii) the self-reported decrease in numbness and tingling. Results: After ozone treatment, 47% of patients experienced a decrease in the grade of CIPN-toxicity ( P = .016), and 67% of patients reported a decrease in numbness and tingling ≥50% ( P = .002). These effects were maintained at 3- and 6- months after the end of O3T. Conclusions: In this retrospective report, patients with persistent numbness and tingling secondary to CIPN showed clinically relevant and long-term improvements after ozone treatment. The magnitude and duration of the observed effects merit further research and support our ongoing clinical trials.
Aggressive Digital Papillary Adenocarcinoma: A Meta-Analysis of the Presentation, Treatment, and Outcomes of a Rare Hand Tumor
Authors: Mendenhall Shaun D. , Graham Emily M. , Lewis Natasha N. , Schmucker Ryan W. , Veith Jacob P. , Koechle Jennifer L. , Neumeister Michael W. 
Published: January 2025

Background: Aggressive digital papillary adenocarcinoma (ADPA) is a rare skin adnexal tumor with a predilection for the hand. The presentation, treatment, and outcomes of ADPA remain poorly defined due to the scarcity of reports and low-level evidence of published findings. Methods: We performed a meta-analysis following Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines with the intent to provide hand surgeons a better understanding of the diagnosis and treatment of the disease. Three additional cases of ADPA from our institution were combined with the results from the systematic review. Results: A total of 238 cases were included in the meta-analysis. Most ADPAs were painful, evolving, and less than 2 cm in size. Regional sentinel lymph node biopsies were performed in 55 patients, of which 25.5% were positive. Overall cohort recurrence and distant metastasis rates were 24.3% and 18.1%, respectively. Patients who obtained clear margins within 6 months of diagnosis had significantly lower rates of recurrence, metastasis, and mortality ( P < .001, P = .04, P = .003, respectively). There were no differences in recurrence or metastasis rates in those who obtained clear margins by excision or amputation ( P = .27 and P = .07, respectively). In patients who died from disease (6.0%), 5.0 years was the average time to death. Conclusions: Aggressive digital papillary adenocarcinoma should be included in the differential diagnosis of hand lesions with unusual presentations or lack of response to other therapies. Clear margins should be obtained within 6 months of diagnosis, and routine surveillance should be provided by an oncologic physician familiar with ADPA as these tumors have high recurrence rates.
“Listening to understand,” exploring postpartum women’s perceptions of their social networks and social support in relation to their health behaviors and weight: A qualitative exploratory study
Authors: Kent-Marvick Jacqueline , Cloyes Kristin G , Clark Ana , Angulo Monica , de la Haye Kayla , Debbink Michelle Precourt , Creal Cristina , Wong Bob , Simonsen Sara E 
Published: January 2025

Background: Postpartum is a critical period to interrupt weight gain across the lifespan, decrease weight-related risk in future pregnancies, promote healthy behaviors that are often adopted during pregnancy, and improve long-term health. Because the postpartum period is marked by unique challenges to a person’s ability to prioritize healthy behaviors, a multi-level/domain approach to intervention beyond the individual-level factors of diet and activity is needed. Objectives: The purpose of this study was to understand postpartum people’s perceptions about the relationship between their social networks and support, and their health behaviors and weight. Design: We used a qualitative descriptive approach and in-depth interviews. Methods: Participants (aged 18+, 12–15 months postpartum, who had a pre-pregnancy body mass index ⩾25) engaged in one-on-one, in-depth interviews conducted via Zoom ( n = 28). Additional qualitative data came from open-ended responses to an online survey ( n = 84) and a personal social-network survey ( n = 84). Qualitative analysis used content and thematic analysis in stages of deductive coding applying codes derived from social-network and support theories, followed by inductive coding. Results: Thirty-eight participants (38.4%) returned to or weighed less than pre-pregnancy weight. We identified two overarching themes grounded in social-network and support theories. They were: (1) normative influence impacts health behaviors, body image, and experiences of weight stigma, and (2) network social support is related to health goals and overall postpartum health. Postpartum networks/support hindered and supported participants’ goals. Partners provided an important source of accountability but were often associated with barriers to healthier behaviors. Conclusion: Our findings reinforce the importance of the social context when considering how to support healthy behaviors and weight during the postpartum period. Healthcare providers should focus on health indicators other than maternal weight, and those wishing to support healthy postpartum behaviors could focus on child and family health, rather than solely on maternal weight and health behaviors.
Psychological impact of an intensive care admission for COVID-19 on patients in the United Kingdom
Authors: Waite Alicia AC , Cherry Mary Gemma , Brown Stephen L , Williams Karen , Boyle Andrew J , Johnston Brian W , Jones Christina , Fisher Peter , Welters Ingeborg D ,   TRIC Network, PIM-COVID Investigators
Published: January 2025

Background: The psychological impact of surviving an admission to an intensive care unit (ICU) with COVID-19 is uncertain. The objective of the study was to assess the prevalence of anxiety, depression and post-traumatic stress disorder (PTSD) symptoms in ICU survivors treated for COVID-19 infection, and identify risk factors for psychological distress. Methods: This observational study was conducted at 52 ICUs in the United Kingdom. Participants, treated for COVID-19 infection during an ICU admission of ⩾24 h, were recruited post-ICU discharge. Self-report questionnaires were completed at 3, 6 and/or 12 months. Symptoms of anxiety and depression were identified using the Hospital Anxiety and Depression Scale. PTSD was assessed using the Impact of Events Scale-6. Demographic, clinical, physical and psychosocial factors were considered as putative predictors of psychological distress. Results: 1620 patients provided consent and 1258 (77.7%) responded to at least one questionnaire, with responses at 3 months ( N = 426), 6 months ( N = 656) and 12 months ( N = 1050) following ICU admission. The following prevalence rates were found at 3, 6 and 12 months, respectively: anxiety in 28.8% (95% CI 24.6–33.1), 30.4% (95% CI 27.0–33.8) and 29.3% (95% CI 26.5–32.1); depression in 25.1% (21.0–29.3), 25.9% (22.7–29.3) and 24.0% (21.5–26.6); and PTSD in 43.5% (38.8–48.2), 44.3% (40.6–48.0) and 43.2% (40.2–46.1) of patients. Risk factors for psychological distress included a previous mental health diagnosis, unemployment or being on sick leave, and a history of asthma or COPD. Conclusion: Clinically significant symptoms of anxiety, depression and PTSD were common and persisted up to 12 months post-ICU discharge.