bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recoil Velocity of Binary Neutron Star Merger Remnants
Authors: Kulkarni Sumeet , Padamata Surendra , Gupta Anuradha 
Published: February 2023

AbstractThe LIGO-Virgo gravitational wave detectors have confidently observed 4 events involving neutron stars: two binary neutron star (BNS) mergers (GW170817 and GW190425), and two neutron star-black hole mergers (GW200105 and GW200115). However, our theoretical understanding of the remnant properties of such systems is incomplete due to the complexities related to the modeling of matter effects and the very high computational cost of corresponding numerical relativity simulations. An important such property is the recoil velocity, which is imparted onto the remnant due to the anisotropic emission of gravitational radiation and the dynamical ejection of matter in the kilonova. In this work, we combine gravitational radiation as well as dynamical ejecta distributions, computed by the Computational Relativity numerical simulations, to get accurate estimates for BNS remnant recoil velocities. We find that recoils due to ejection of matter dominate those caused by gravitational wave emission. Knowledge of BNS remnant recoil velocities is important in determining if the remnant is retained by its environment for future hierarchical mergers which, in turn, can form binaries with black holes in the so-called lower mass gap of ∼ 3 – 5M⊙.
The search for Continuous Gravitational Waves: the journey to discovery
Authors: Leaci Paola 
Published: February 2023

AbstractContinuous gravitational Waves (CWs) are a very promising, not yet detected, and interesting class of persistent and semi-periodic signals. They are emitted mainly by rapidly rotating asymmetric neutron stars, with frequencies that are well covered by the [10-3 000] Hz range of the advanced LIGO-Virgo detectors. Due to the expected small degree of asymmetry of a neutron star, the search for this kind of signals is extremely challenging, and can be very computationally expensive when the source parameters are not known or not well constrained. CW detection from a spinning neutron star will allow us to characterize its structure and properties, making this source an unparalleled laboratory for studying several key issues in fundamental physics and relativistic astrophysics, in conditions that cannot be reproduced on Earth. The most recent methodologies used in CW searches will be discussed, and the latest results from the third advanced LIGO-Virgo observational run will be presented. A summary of future prospects to feasibly detect such feeble signals as the detector performance improves, and ever-more-sensitive and robust data-analysis algorithms are implemented, will be also outlined.
The African Court on Human and Peoples’ Rights: forging a jurisdictional frontier in post-colonial human rights
Authors: Sanchez Maria A. 
Published: February 2023

AbstractThe African Court on Human and Peoples’ Rights (ACtHPR) was finally established in 2004 after decades of negotiations. Despite forty years of resistance from governments who were reluctant to sacrifice sovereignty to a supranational body, the African Charter on Human and Peoples’ Rights and its Protocol grant the ACtHPR far-reaching authority relative to other regional human rights courts. How did the ACtHPR end up with an expansive jurisdiction that is unprecedented among regional courts? This analysis proposes that legal experts’ ability to capture control over vital stages in the drafting of the African Charter and Protocol, thus limiting the influence of political advisors, yielded an institutional design that facilitated the ACtHPR's unique mandate. Furthermore, colonial legacies in newly-independent states pushed the founders of the African human rights system to envision an innovative, post-colonial human rights framework that integrated a wide-reaching spectrum of civil, political, economic, social and cultural rights.
Structured tracking of alcohol reinforcement (STAR) for basic and translational alcohol research
Authors: Brown Alex R. , Branthwaite Hannah E. , Farahbakhsh Zahra Z. , Mukerjee Snigdha , Melugin Patrick R. , Song Keaton , Noamany Habiba , Siciliano Cody A. 
Published: February 2023

AbstractThere is inherent tension between methodologies developed to address basic research questions in model species and those intended for preclinical to clinical translation: basic investigations require flexibility of experimental design as hypotheses are rapidly tested and revised, whereas preclinical models emphasize standardized protocols and specific outcome measures. This dichotomy is particularly relevant in alcohol research, which spans a diverse range of basic sciences in addition to intensive efforts towards understanding the pathophysiology of alcohol use disorder (AUD). To advance these goals there is a great need for approaches that facilitate synergy across basic and translational areas of nonhuman alcohol research. In male and female mice, we establish a modular alcohol reinforcement paradigm: Structured Tracking of Alcohol Reinforcement (STAR). STAR provides a robust platform for quantitative assessment of AUD-relevant behavioral domains within a flexible framework that allows direct crosstalk between translational and mechanistically oriented studies. To achieve cross-study integration, despite disparate task parameters, a straightforward multivariate phenotyping analysis is used to classify subjects based on propensity for heightened alcohol consumption and insensitivity to punishment. Combining STAR with extant preclinical alcohol models, we delineate longitudinal phenotype dynamics and reveal putative neuro-biomarkers of heightened alcohol use vulnerability via neurochemical profiling of cortical and brainstem tissues. Together, STAR allows quantification of time-resolved biobehavioral processes essential for basic research questions simultaneous with longitudinal phenotyping of clinically relevant outcomes, thereby providing a framework to facilitate cohesion and translation in alcohol research.
Interstrand crosslinking of homologous repair template DNA enhances gene editing in human cells
Authors: Ghasemi Hannah I. , Bacal Julien , Yoon Amanda C. , Tavasoli Katherine U. , Cruz Carmen , Vu Jonathan T. , Gardner Brooke M. , Richardson Chris D. 
Published: February 2023

AbstractWe describe a strategy to boost the efficiency of gene editing via homology-directed repair (HDR) by covalently modifying the template DNA with interstrand crosslinks. Crosslinked templates (xHDRTs) increase Cas9-mediated editing efficiencies by up to fivefold in K562, HEK293T, U2OS, iPS and primary T cells. Increased editing from xHDRTs is driven by events on the template molecule and requires ataxia telangiectasia and Rad3-related (ATR) kinase and components of the Fanconi anemia pathway.
An alternate hybrid PWM for uniform thermal sharing in single phase voltage-source inverter
Authors: Kiranmai K. S. P. , Damodaran R. V. , Hushki M. , Shareef H. 
Published: February 2023

AbstractThe most prevalent reason for IGBT failure in voltage-source inverter (VSI) is thermal stress, which is influenced by the topology and modulation technique adopted. Hence, it is crucial to understand the impact of common sinusoidal pulse width modulation (PWM) strategies on the thermal behavior of VSI and develop improved PWM techniques. This paper presents an alternate hybrid PWM (AHPWM) switching sequence for a single-phase VSI to decrease its thermal stress and prolong its lifetime. To evaluate the number of cycles to failure of VSI, power loss and thermal analysis were conducted for VSI with AHPWM and compared with conventional PWMs. The thermal cycles experienced by IGBTs with different modulation techniques were experimentally validated using a laboratory prototype of VSI. These findings suggest that by employing AHPWM, the likelihood of VSI failure is reduced by at least one-and-a-half times, resulting in lower VSI maintenance costs.
Days alive and out of hospital at 30 days and outcomes of off-pump coronary artery bypass grafting
Authors: Oh Ah Ran , Lee Seung-Hwa , Park Jungchan , Min Jeong-Jin , Lee Jong-Hwan , Yoo Seung Yeon , Kwon Ji-Hye , Choi Dan-Cheong , Kim Wooksung , Cho Hyun Sung 
Published: February 2023

AbstractDays alive and out of hospital (DAOH) is a simple estimator based on the number of days not in hospital within a defined period. In cases of mortality within the period, DAOH is regarded as zero. It has not been validated solely in off-pump coronary artery bypass grafting (OPCAB). This study aimed to demonstrate a correlation between DAOH and outcome of OPCAB. We identified 2211 OPCAB performed from January 2010 to August 2016. We calculated DAOH at 30 and 60 days. We generated a receiver-operating curve and compared outcomes. The median duration of hospital stay after OPCAB was 6 days. The median DAOH values at 30 and 60 days were 24 and 54 days. The estimated thresholds for 3-year mortality for DAOH at 30 and 60 days were 20 and 50 days. Three-year mortality was higher for short DAOH (1.2% vs. 5.7% and 1.1% vs. 5.6% DAOH at 30 and 60 days). After adjustment, the short DAOH 30 group showed significantly higher mortality during 3-year follow-up (hazard ratio 3.07; 95% confidence interval 1.45–6.52; p = 0.004). DAOH at 30 days after OPCAB showed a correlation with 3-year outcomes. DAOH 30 might be a reliable long-term outcome measure that can be obtained within 30 days after surgery.
Investigation on CMB monopole and dipole using blackbody radiation inversion
Authors: Dhal Somita , Paul R. K. 
Published: February 2023

AbstractThe COBE/FIRAS dataset is used to calculate the Cosmic Microwave Background temperature and the uncertainty using the Blackbody Radiation Inversion (BRI) method. In this research work, the procedure is somewhat comparable to the mixing of weighted blackbodies in the case of the dipole. The temperature and its spreading for the monopole and dipole, respectively, are 2.741 ± 0.018 K and 2.748 ± 0.270 K. This dipole spreading exceeds the spreading predicted by taking relative motion into account (i.e., 3.3 × 10−3 K). The comparison of the probability distributions for the monopole spectrum, dipole spectrum, and their resultant is also displayed. It is shown that the distribution is symmetrically orientated. We estimated the µ and y-distortions by interpreting the spreading as the distortion and found that they are of the order of 10−4 and 10−5, respectively, for the monopole spectrum and 10−2 for the dipole spectrum. The paper also highlights the effectiveness of the BRI method and hints at future applications in the thermal nature of the early universe.
Pet dog facial expression recognition based on convolutional neural network and improved whale optimization algorithm
Authors: Mao Yan , Liu Yaqian 
Published: February 2023

AbstractPet dogs are our good friends. Realizing the dog’s emotions through the dog's facial expressions is beneficial to the harmonious coexistence between human beings and pet dogs. This paper describes a study on dog facial expression recognition using convolutional neural network (CNN), which is a representative algorithm model of deep learning. Parameter settings have a profound impact on the performance of a CNN model, improper parameter setting will make the model exposes several shortcomings, such as slow learning speed, easy to fall into local optimal solution, etc. In response to these shortcomings and improve the accuracy of recognition, a novel CNN model based on the improved whale optimization algorithm (IWOA) called IWOA–CNN is applied to complete this recognition task. Unlike human face recognition, a dedicated face detector in Dlib toolkit is utilized to recognize the facial region, and the captured facial images are augmented to build an expression dataset. The random dropout layer and L2 regularization are introduced into the network to reduce the number of transmission parameters of network and avoid over fitting. The IWOA optimizes the keep probability of the dropout layer, the parameter λ of L2 regularization and the dynamic learning rate of gradient descent optimizer. Carry out a comparative experiment of IWOA–CNN, Support Vector Machine, LeNet-5 and other classifiers for facial expression recognition, its results demonstrate that the IWOA–CNN has better recognition effect in facial expression recognition and also explain the efficiency of the swarm intelligence algorithm in dealing with model parameter optimization.
A survey of barriers and facilitators to ultrasound use in low- and middle-income countries
Authors: Ginsburg Amy Sarah , Liddy Zylee , Khazaneh Parsa T. , May Susanne , Pervaiz Farhan 
Published: February 2023

AbstractPoint-of-care ultrasound has the potential to help inform assessment, diagnosis, and management of illness in low- and middle-income countries (LMIC). To better understand current ultrasound use, barriers and facilitators to use, and perceptions and practices in LMIC, we conducted an anonymous online global survey targeting healthcare providers training and using ultrasound in LMIC. A total of 241 respondents representing 62 countries participated and most were physicians working in publicly-funded urban tertiary hospitals in LMIC. Most had received ultrasound training (78%), reported expertise (65%) and confidence (90%) in ultrasound use, and had access to ultrasound (88%), utilizing ultrasound most commonly for procedures and for evaluations of lungs, heart, and trauma. Access to an ultrasound machine was reported as both the top barrier (17%) and top facilitator (53%); other common barriers included access to education and training, cost, and competition for use and other common facilitators included access to a probe, gel, and electricity, and acceptance by healthcare providers, administrators, and patients. Most (80%) noted ultrasound access was important and 96% agreed that ultrasound improves quality of care and patient outcomes. Improving access to low-cost ultrasound equipment is critical to increasing ultrasound use among those who are trained.
Immature platelet fraction predicts early marrow recovery after severe chemotherapy associated neutropenia
Authors: Salvador Christina , Meryk Andreas , Hetzer Benjamin , Bargehr Caroline , Kropshofer Gabriele , Meister Bernhard , Anliker Markus , Crazzolara Roman 
Published: February 2023

AbstractFebrile neutropenia secondary to chemotherapy is one of the most critical complications in cancer treatment. The aim of this study was to determine if an increase in the percentage of immature platelet fraction (IPF%) might predict early neutrophil recovery following cytostatic-dependent aplasia. A retrospective cohort study compared serial complete blood counts and the level of C-reactive protein (CRP) following induction chemotherapy for Ewing sarcoma and Non-Ewing sarcoma patients. The measurements were taken on a Sysmex XE-2100 instrument. A total of 287 paired samples from 28 children after the first cycle of chemotherapy were analyzed to test if an increase in the IPF% anticipated the CRP peak and recovery of neutrophil count. The chemotherapy associated nadir of neutrophils, reticulocytes and platelets was reached at 9.7 ± 1.5, 11.0 ± 1.7 and 11.9 ± 0.9 days (mean ± SD) respectively, in Ewing sarcoma patients. Still in severe neutropenia, IPF% was the first parameter that significantly increased and anticipated the CRP peak (11.9 ± 1.6 days, mean ± SD). The IPF% continuously increased (maximum = 6.56% ± 2.8%, mean ± SD) and peaked at 12.2 ± 1.4 days (mean ± SD) after commencement of chemotherapy. Compared to neutrophil recovery (14.6 ± 1.4 days, mean ± SD), the IPF% peak was anticipated by 2.4 days (p = 0.0085). Although variably treated, in non-Ewing sarcoma patients the effect was similar and the IPF% peak anticipated neutrophil recovery by 6.8 ± 4.7 days (p < 0.01). IPF% increased significantly at > 48 h before neutrophil recovery in patients treated with chemotherapy. IPF% is an inexpensive parameter and may be valuable in the management of febrile neutropenia.
Influence of carbon nanotube suspensions on Casson fluid flow over a permeable shrinking membrane: an analytical approach
Authors: Mahesh Rudraiah , Mahabaleshwar Ulavathi Shettar , Sofos Filippos 
Published: February 2023

AbstractThe present work employs the single-wall carbon nanotube (SWCNT) and multiwall carbon nanotube (MWCNT) models on axisymmetric Casson fluid flow over a permeable shrinking sheet in the presence of an inclined magnetic field and thermal radiation. By exploiting the similarity variable, the leading nonlinear partial differential equations (PDEs) are converted into dimensionless ordinary differential equations (ODEs). The derived equations are solved analytically, and a dual solution is obtained as a result of the shrinking sheet. The dual solutions for the associated model are found to be numerically stable once the stability analysis is conducted, and the upper branch solution is more stable compared to lower branch solutions. The impact of various physical parameters on velocity and temperature distribution is graphically depicted and discussed in detail. The single wall carbon nanotubes have been found to achieve higher temperatures compared to multiwall carbon nanotubes. According to our findings, adding carbon nanotubes volume fractions to convectional fluids can significantly improve thermal conductivity, and this can find applicability in real world applications such as lubricant technology, allowing for efficient heat dissipation in high-temperatures, enhancing the load-carrying capacity and wear resistance of the machinery.
Intraoperative mean arterial pressure and acute kidney injury after robot-assisted laparoscopic prostatectomy: a retrospective study
Authors: Kim Tae Lim , Kim Namo , Shin Hye Jung , Cho Matthew R. , Park Hae Ri , Kim So Yeon 
Published: February 2023

AbstractIntraoperative hemodynamics can affect postoperative kidney function. We aimed to investigate the effect of intraoperative mean arterial pressure (MAP) as well as other risk factors on the occurrence of acute kidney injury (AKI) after robot-assisted laparoscopic prostatectomy (RALP). We retrospectively evaluated the medical records of 750 patients who underwent RALP. The average real variability (ARV)-MAP, standard deviation (SD)-MAP, time-weighted average (TWA)-MAP, area under threshold (AUT)-65 mmHg, and area above threshold (AAT)-120 mmHg were calculated using MAPs collected within a 10-s interval. Eighteen (2.4%) patients developed postoperative AKI. There were some univariable associations between TWA-MAP, AUT-65 mmHg, and AKI occurrence; however, multivariable analysis found no association. Alternatively, American Society of Anesthesiologists physical status ≥ III and the low intraoperative urine output were independently associated with AKI occurrence. Moreover, none of the five MAP parameters could predict postoperative AKI, with the area under the receiver operating characteristic curve values for ARV-MAP, SD-MAP, TWA-MAP, AUT-65 mmHg, and AAT-120 mmHg being 0.561 (95% confidence interval [CI], 0.424–0.697), 0.561 (95% CI, 0.417–0.704), 0.584 (95% CI, 0.458–0.709), 0.590 (95% CI, 0.462–0.718), and 0.626 (95% CI, 0.499–0.753), respectively. Therefore, intraoperative MAP changes may not be a determining factor for AKI after RALP.
Highly localized, efficient, and rapid photothermal therapy using gold nanobipyramids for liver cancer cells triggered by femtosecond laser
Authors: Liu Xiao , Zhou Wei , Wang Tianjun , Miao Sen , Lan Sheng , Wei Zhongchao , Meng Zhao , Dai Qiaofeng , Fan Haihua 
Published: February 2023

AbstractIn this study, the photothermal effect and up-conversion florescence imaging effect of gold nanobipyramids in liver cancer cells are investigated theoretically and experimentally to explore the photothermal ablation tumor therapy with higher photothermal conversion efficiency, shorter laser action time, smaller action range and lower laser power. The small-size gold nanobipyramids with good biocompatibility and infrared absorption peak located in the first biological window are synthesized. Femtosecond laser is focused on the nanobipyramids clusters in cells and the cells die after being irradiated for 20 s at a power as low as 3 mW. In contrast, the control cells die after irradiation with 30 mW laser for 3 min. The theoretical simulation results show that: under femtosecond laser irradiation, the local thermal effect of gold nanoclusters is produced in the range of hundreds of square nanometers and the temperature rises by 516 °C in 106 picoseconds. This therapy reduces the treatment time to seconds level, and the treatment range to square micrometer level, the power to milliwatt level. In this treatment, cells die by apoptosis rather than necrosis, which reduces inflammation. This result opens up a new way to develop photothermal ablation therapy with less side effects and more minimally invasive.
A model to predict the prognosis of diffuse large B-cell lymphoma based on ultrasound images
Authors: Lu Wenjuan , Chen Wenqin , Zhou Yasu , Yuan Ya , Shu Hua , Deng Hongyan , Ye Xinhua 
Published: February 2023

AbstractThe purpose of this paper was to assess the value of ultrasonography in the prognosis of diffuse large b-cell lymphoma (DLBCL) by developing a new prognostic model. One hundred and eleven DLBCL patients with complete clinical information and ultrasound findings were enrolled in our study. Univariate and multivariate regression analyses were used to identify independent risk factors for progression-free survival (PFS) and overall survival (OS). Receiver operator characteristic (ROC) curves were plotted and the corresponding area under the curve (AUC) was calculated to assess the accuracy of the international prognostic index (IPI) and new model in DLBCL risk stratification. The results suggested that hilum loss and ineffective treatment were independent risk variables for both PFS and OS in DLBCL patients. Additionally, the new model that added hilum loss and ineffective treatment to IPI had a better AUC for PFS and OS than IPI alone (AUC: 0.90, 0.88, and 0.82 vs. 0.71, 0.74, and 0.68 for 1-, 3-, and 5-year PFS, respectively; AUC: 0.92, 0.85 and 0.86 vs. 0.71, 0.75 and 0.76, for 1-, 3-, and 5-year OS, respectively). The model based on ultrasound images could better suggest PFS and OS of DLBCL, allowing for better risk stratification.
A Scoping Review of Auditory Dysfunction After Childhood Traumatic Brain Injury
Authors: Riccardi Jessica Salley 
Published: February 2023

Purpose:
The purpose of this scoping review was to gain an understanding of the evidence available on auditory dysfunction after childhood traumatic brain injury (TBI) and identify limitations, clinical implications, and future directions for speech-language pathology and audiology practice and research.

Method:
This scoping review of the literature followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews guidelines.

Results:

A total of eight articles met inclusion for this scoping review. All studies were observational studies (
n
= 4 with controls,
n
= 4 without controls). Age at injury, injury severity, time postinjury, and age at time of study varied across the included studies. Three major topics related to childhood TBI were addressed among the included studies: (a) prevalence of auditory dysfunction (
n
= 5), (b) functional outcomes and biological markers related to auditory processing (
n
= 2), and (c) clinical presentation of auditory dysfunction (
n
= 2).

Conclusions:
This review highlights the particular lack of experimental evidence related to risk and protective factors and assessment and management strategies related to auditory dysfunction after childhood TBI. There is a major need for more research and research of higher rigor to be conducted with individuals who experienced a childhood TBI to support audiologists' and speech-language pathologists' evidence-based decision making to improve long-term functional outcomes for children with TBI.