bluuebunny/crossref_metadata_2025_split huggingface dataset:
Driving innovation through servant leadership in higher education: Unveiling the serial mediating mechanisms of subjective well‐being and knowledge sharing
Authors: Nawaz Asif , Gilal Faheem Gul , Soomro Muhammad Ismail , Gilal Rukhsana Gul , Channa Khalil Ahmed 
Published: July 2023

AbstractAcademic research consistently emphasizes the significance of leadership style in driving performance outcomes within organizations. However, there remains a notable dearth of studies examining the association between servant leadership (SL) and employees' objective innovative performance. To bridge this research gap, this study adopts a dual theoretical lens, integrating the Conservation of Resource Theory and Social Exchange Theory, to explore the impact of SL on innovative performance specifically in the context of higher education institutions. In addition, this research endeavors to elucidate the mediating roles of subjective well‐being and knowledge sharing in the relationship between SL style and innovative performance. To this end, data were collected from employees and their peers in higher education institutions, and a partial least square (PLS)‐based structural equation modeling technique was used for analysis. The findings reveal a positive association between SL and employees' innovative performance. Furthermore, subjective well‐being significantly mediates the relationship between SL and innovative performance, while knowledge sharing has a trivial mediating effect. This study contributes to the literature by addressing the research gap in understanding the role of SL in enhancing innovative performance in higher education. The insights gained from this research can provide managers with valuable guidance on leveraging SL to foster employees' innovative performance.
Hydrodynamics rather than type of coastline shapes self‐recruitment in anemonefishes
Authors: Sato Masaaki , Honda Kentaro , Nakamura Yohei , Bernardo Lawrence Patrick C. , Bolisay Klenthon O. , Yamamoto Takahiro , Herrera Eugene C. , Nakajima Yuichi , Lian Chunlan , Uy Wilfredo H. , Fortes Miguel D. , Nadaoka Kazuo , Nakaoka Masahiro 
Published: July 2023

AbstractMany marine species have a pelagic larval phase that undergo dispersal among habitats. Studies on marine larval dispersal have revealed a large variation in the spatial scale of dispersal and self‐recruitment. However, few studies have investigated the influence of types of coastline (e.g., bay vs. open coast) on marine larval dispersal. Bays or lagoons generally enhance the retention of larvae, while larvae are more likely to be flushed by strong currents in open coasts. To examine associations between larval dispersal, coastline type, and hydrodynamics, we compared fin‐scale dispersal patterns, self‐recruitment, and local retention (LR) of two anemonefishes (Amphiprion frenatus and Amphiprion perideraion) between a semi‐enclosed bay and an open coast in the Philippines combining genetic parentage analysis and biophysical dispersal modeling. Contrary to our expectations, parentage analysis revealed lower estimates of self‐recruitment in the semi‐closed bay (0%) than in the open coast (14–15%). The result was consistent with dispersal simulations predicting lower LR and self‐recruitment in the semi‐closed bay (0.4% and 19%) compared to the open coast (2.9% and 38%). Dispersal modeling also showed that cross‐shore currents toward offshore were much stronger around the semi‐closed bay and were negatively correlated with LR and self‐recruitment. These results suggest that stronger cross‐shore currents around the semi‐closed bay transport anemonefish larvae to the offshore and mainly contributed to the lower self‐recruitment. Our results highlight importance of hydrodynamics on larval dispersal and difficulty in predicting self‐recruitment from coastline type alone.
Ball Lens‐Assisted Cellphone Imaging with Submicron Resolution
Authors: Jin Boya , Jean Amstrong R. , Maslov Alexey V. , Astratov Vasily N. 
Published: July 2023

AbstractOne of the most significant developments in life sciences—the discovery of bacteria and protists—was accomplished by Antoni van Leeuwenhoek in the 17thcentury using a single ball lens microscope. It is shown that the full potential of single lens designs can be realized in a contact mode of imaging by ball lenses with a refractive index of n≈ 2, suitable for developing compact cellphone‐based microscopes. The quality of imaging is comparable to basic compound microscopes, but with a narrower field‐of‐view, and is demonstrated for various biomedical samples. The maximal magnification (M > 50) with the highest resolution (≈0.66 µm atλ= 589 nm) is achieved for imaging of nanoplasmonic structures by ball lenses made from LASFN35 glass, the index of which is tuned nearn =2 using chromatic dispersion. Due to limitations of geometrical optics, the imaging theory is developed based on an exact numerical solution of the Maxwell equations, including spherical aberration and the nearfield coupling of a point source. The modeling is performed using multiscale analysis: from the field propagation inside ball lenses with diameters 30 < D/λ < 4000 to the formation of the diffracted field at distances of ≈105λ. It is shown that such imaging enables the transition from pixel‐ to diffraction‐limited resolution in cellphone microscopy.
The interplay of information order and locus of attention on the truth effect in healthy food advertisements
Authors: Jang Jung Min 
Published: July 2023

AbstractThe perceived truthfulness of advertised claims plays a vital role in healthy food marketing, shaping positive consumer responses. This study investigates how the presentation order of healthy ingredients and food products commonly featured in advertisements influences the perceived truthfulness of these claims, also known as the truth effect, using the congruency effect as a theoretical framework. Two studies were conducted to explore the impact of the compatibility between a contextual factor (presentation order) and cultural/individual difference (locus of attention) on the subjective experience of processing fluency, and how it subsequently enhances the truth effect, wherein consumers believe the advertised claims about the product. Studies 1 and 2 revealed that individuals, depending on their locus of attention, are more likely to exhibit a heightened truth effect when the food product is presented first, followed by the healthy ingredient as an attribute, or when the information is presented in the opposite order. Additionally, the observed effect was found to be completely mediated by processing fluency. These findings make theoretical and practical contributions by highlighting the role of the congruency effect as a novel determinant of the truth effect.
CNOT4 suppresses nonsmall cell lung cancer progression by promoting the degradation of PAF1
Authors: Zhang Biao , Zhao Bin , Han Song , Chen Shaomu 
Published: July 2023

AbstractCCR4‐NOT transcription complex subunit 4 (CNOT4) and RNA polymerase II‐associated factor, homolog (Saccharomyces cerevisiae) (PAF1) are implicated in nonsmall cell lung cancer (NSCLC). However, the molecular mechanism of their interaction in NSCLC progression is unknown. The expression of PAF1 and CNOT4 in human NSCLC tissues was detected by quantitative polymerase chain reaction. A549 cells that stably expressed CNOT4 and/or PAF1 were established. Western blot analysis and co‐immunoprecipitation experiments were performed to reveal the interaction between CNOT4 and PAF1. Proliferation, migration, epithelial–mesenchymal transition (EMT), and colony formation assays were performed to determine the effect of CNOT4‐PAF1 axis on NSCLC metastasis and stemness. Xenograft mouse tumor model was established, and tumor progression, EMT, and stemness were evaluated. It was found that CNOT4 expression was downregulated, whereas PAF1 expression was upregulated in human NSCLC tissues. CNOT4 facilitated the ubiquitination and degradation of PAF1 via the 26S proteasome. CNOT4 overexpression inhibited NSCLC progression, whereas PAF1 overexpression enhanced the proliferation, migration, and stemness of NSCLC, both in vitro and in vivo. Our results suggest that CNOT4‐PAF1 axis modulates NSCLC metastasis and stemness, and may serve as potential therapeutic targets for lung cancer treatment.
Exposure to endogenous and exogenous sex hormones and reproductive history influence prognosis in women with ALS
Authors: Gonzalez Deniselle M. Claudia , Bettini Mariela , Garrido Rosa M. , Meyer Maria , Lara Agustina , Garay Laura I. , Casas Sebastian , Fulgenzi Ernesto , Nuñez Myriam , Rugiero Marcelo F. , De Nicola Alejandro F. , Gargiulo‐Monachelli Gisella 
Published: July 2023

AbstractIntroduction/AimsAmyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with a higher incidence in men suggesting an influence of sex steroids. Our objective was to investigate past exposure to endogenous and synthetic steroids in female ALS patients and controls.MethodsWe administered a questionnaire to 158 postmenopausal women (75 ALS patients and 83 controls). We calculated reproductive time span (RTS), lifetime endogenous estrogen (LEE) and progesterone exposures (LPE), oral contraceptive pill (OCP) use, and reproductive history.ResultsALS patients showed shorter LEE and LPE, a lower proportion of breast cancer, and 11% showed no history of pregnancies vs. 4% of controls. Odds ratios (ORs) showed that <17 y of LEE and a delayed menarche (>13 y) constitute risk factors for ALS [OR = 2.1 (95% confidence interval {CI}, 1.08–4.2); and OR = 2.4 (95% CI, 1.1–5.1) respectively]. According to Cox survival analysis, for each year the LEE increased over 17 y, it was independently associated with longer survival [hazard ratio (HR) = 0.37 (95% CI, 0.16–0.85)] after adjusting for smoking, age and site of onset. Multivariate regression analysis demonstrated that for each month using OCP for longer than 40 mo increased the risk of ALS [adjusted OR = 4.1 (95% CI, 1.2–13.8)].DiscussionThus, longer exposure to endogenous female sex steroids increased survival and reduced ALS susceptibility. In contrast, longer exposure to synthetic sex steroids showed a negative impact by reducing the production of endogenous female sex steroids or due to crossover with other steroid receptors. Given the neuroprotective effects of sex steroids, we suggest that abnormalities of neuroendocrine components may alter motor function in women with ALS.
Achievement, Ascription, andMana: A Step beyond Binary Opposition in Studying Leadership in Oceania
Authors: Faucounau Francois‐Xavier 
Published: July 2023

ABSTRACTThis paper critiques the recent use of Marshall Sahlins' model, which opposes big men to chiefs to establish a contrast between Austronesian and Non‐Austronesian communities in Oceania. By reviewing Sahlins' model and drawing upon Oceania‐wide ethnographic work, I argue that the two opposed paradigms underlying Sahlins' model of leadership, namely achievement and ascription, are in fact entangled in practices and in ideologies. I contend that the cooccurrence of ‘achievement’ and ‘ascription’ is widely supported by ethnographies of Oceania; that these two features can simultaneously characterize a single leadership position; and that this dual aspect of leadership is conveyed in Remote Oceania by the indigenous concept of mana. This suggests that the historical analysis of leadership in Oceania should move beyond this the achievement/ascription dichotomy. Thus, instead of mapping the region in terms of their absence or presence, it is more productive to analyse how these features articulate, or to focus on other aspects of leadership in Oceania such as the relation between leaders and deities or ancestors.
Lithium‐Ion Battery Cathode Recycling through a Closed‐Loop Process Using a Choline Chloride‐Ethylene Glycol‐Based Deep‐Eutectic Solvent in the Presence of Acid
Authors: Yetim Delphine , Svecova Lenka , Leprêtre Jean‐Claude 
Published: July 2023

AbstractThis study evaluates the ability of a choline chloride:ethylene glycol‐based deep eutectic solvent (DES) to dissolve lithium cobalt oxide (LCO) which is used as a cathode active material in Li‐ion batteries. Both a commercial powder and spent cathodes have been used. It was demonstrated that if HCl is added in a small proportion, a rapid and efficient LCO dissolution can be achieved. Indeed, if more than three protons are added per one cobalt atom present in the LCO structure, a complete dissolution of the material is accomplished within 2 h at 80 °C. This result might be considered as a viable alternative compared to the literature where much longer reaction times and higher temperatures are applied to achieve similar results with the same DES system used either pure or in presence of additional reducing agents. It was further demonstrated that Co and Li can be fully precipitated after Li2CO3 addition. This precipitation does neither pollute the DES nor leads to its degradation provided the pH does not exceed 10. Finally, it was shown that two additional reuse cycles can be carried out without any decrease of recovery efficiency, while no degradation products have been detected within the DES phase.
Use of gastrointestinal prokinetics and the risk of parkinsonism: A population‐based case‐crossover study
Authors: Kim Eunji , Kim Siin , Suh Hae Sun 
Published: July 2023

AbstractBackgroundThe disease burden of parkinsonism is extremely costly in the United States. Unlike Parkinson's disease, drug‐induced parkinsonism (DIP) is acute and reversible; exploring the causative drug is important to prevent DIP in patients at high‐risk of parkinsonism.ObjectiveTo examine whether the use of gastrointestinal (GI) prokinetics is associated with an increased risk of parkinsonism.MethodsWe conducted a case‐crossover study using nationally representative data. We included patients who were newly diagnosed with parkinsonism (ICD‐10 G20, G21.1, G25.1) between January 1, 2007 and December 1, 2015. The first prescription date of G20, G21.1, or G25.1 diagnoses was defined as the index date (0 day). Patients with prior extrapyramidal and movement disorders or brain tumors were excluded. We assessed the exposure within the risk (0–29 days) and control periods (60–89 days), before or on the index date. Conditional logistic regression estimated the adjusted odds ratio (aOR) for parkinsonism.ResultsOverall, 2268 and 1674 patients were exposed to GI prokinetics during the risk and control periods, respectively. The use of GI prokinetics significantly increased the occurrence of parkinsonism (aOR = 2.31; 95% Confidence Interval [CI], 2.06–2.59). The use of GI prokinetics was associated with a higher occurrence of parkinsonism in elderly patients (≥65 years old; aOR = 2.69; 95% CI, 2.30–3.14) than in younger patients (aOR = 1.90; 95% CI, 1.59–2.27).ConclusionsThe use of GI prokinetics was significantly associated with higher occurrences of parkinsonism, necessitating close consideration when using GI prokinetics.
The effect of polymeric films of hydroxypropyl methylcellulose (HPMC)/chitosan on ofloxacin release, diffusion, and biological activity
Authors: Jaber Saif Aldeen , Saadh Mohamed , Obeid Mohammad A. 
Published: July 2023

AbstractInfectious diseases caused by resistant bacteria have been investigated by several researchers recently. Ofloxacin is a quinolone antibiotic used against resistant microorganisms and in different routes of administration. Transdermal drug delivery is used to reduce drug toxicity, avoid first‐pass metabolism, and reduce fluctuations in drug concentration in the body. Ofloxacin was formulated in a transdermal polymeric formula using hydroxypropyl methyl cellulose (HPMC) and chitosan at different ratios in the presence of palmitic acid as a permeation enhancer. Physical characterization, drug release and diffusion, drug matrix association, and antimicrobial assay have been investigated using different techniques including HPLC, fourier‐transform infrared spectroscopy (FTIR), Franz cells diffusion, and UV spectroscopy. Ofloxacin release was successfully accomplished in many polymeric formulas containing a high ratio of HPMC with a maximum drug release of 53%. Formulas selected for antimicrobial assay indicate that sustained release patches have successfully inhibited microbial and biofilm growth with a percentage inhibition of more than 90%. In conclusion, antibiotics can be formulated in transdermal polymeric film to target skin infection and reduce drug toxicity and avoid drug first metabolism for drugs reaching systemic circulation which has a direct influence on drug activity.
Challenges of inclusive schooling for children and adolescents with congenital heart disease: A phenomenological study
Authors: Violant‐Holz Verónica , Muñoz‐Violant Sarah , Rodrigo‐Pedrosa Olga 
Published: July 2023

AbstractEducational attainment is closely associated with health. The objective is to explore the extent to which children and adolescents with congenital heart disease (CHD) are afforded the same educational and socialization opportunities as their healthy peers. We used a qualitative phenomenological design with convenience sampling. Data gathered 27 semistructured interviews: children with CHD (n = 9), parents (n = 10), and professionals (n = 8) in Catalonia, Spain. Interview transcripts were coded using the constant comparative method and analyzed using ATLAS.ti software. The analysis revealed three themes describing the experience of schooling for children with CHD: (1) Empowering and enabling a child with CHD to achieve academically and engage socially is a challenge for parents; (2) Teachers lack the resources and specific skills necessary to meet the diversity needs of children with CHD; (3) Parents and teachers have low expectations regarding the academic achievement of a child with CHD. Further application of the constant comparison method yielded a core theme: (4) Children with CHD experience exclusion from peer group social learning activities. Further efforts are needed for more effective collaboration and coordination between educational and health professionals to provide support for teachers and families and enable children to be better integrated within schools.
Content comparison of the EORTC CAT Core, SF‐36, FACT‐G, and PROMIS role and social functioning measures based on the International Classification of Functioning, Disability and Health
Authors: Pilz Micha J. , Rothmund Maria , Lidington Emma , Piccinin Claire , Arraras Juan I. , Groenvold Mogens , Holzner Bernhard , van Leeuwen Marieke , Petersen Morten Aa. , Schmidt Heike , Young Teresa , Giesinger Johannes M. ,   EORTC Quality of Life Group
Published: July 2023

AbstractObjectivesIn line with the World Health Organizations' health definition, patient‐reported outcome (PRO) measures frequently cover aspects of social health. Our study aimed to evaluate the role functioning (RF) and social functioning (SF) contents assessed by PRO measures commonly used in cancer patients.MethodsWe analysed the item content of the SF and RF domains of the EORTC CAT Core, the EORTC QLQ‐C30, the SF‐36, and the FACT‐G as well as the PROMIS item bank covering the Ability to Participate in Social Roles and Activities. Following an established methodology we linked item content to the International Classification of Functioning, Disability and Health (ICF) framework.ResultsThe content of 85 items was assigned to three ICF components (‘Activities and Participation’, ‘Body Functions’, and ‘Environmental Factors’). The EORTC CAT Core RF items were mostly related to the first‐level ICF categories ‘Domestic life’ and ‘Community, social and civic life’, while its SF item bank focused on ‘Interpersonal interactions and relationships’. These three categories were also covered by the PROMIS social participation item bank. The FACT‐G Social/Family scale focused on environmental factors (‘Support and Relationships’ and ‘Attitudes’) while the SF‐36 Role‐physical/emotional scales had a stronger focus on ‘General tasks and demands’ and ‘Major life areas’.ConclusionsOur results highlight conceptual overlap and differences among PRO measures for the assessment of social health in cancer. This information may help to select the most appropriate measure for a specific setting or study purpose and to better understand the possibilities of linking scores across different PRO measures.
Saliva as a noninvasive sampling matrix for therapeutic drug monitoring of intravenous busulfan in Chinese patients undergoing hematopoietic stem cell transplantation: A prospective population pharmacokinetic and simulation study
Authors: Xu Baohua , Yang Ting , Zhou Jianxing , Zheng You , Wang Jingting , Liu Qingxia , Li Dandan , Zhang Yifan , Liu Maobai , Wu Xuemei 
Published: July 2023

AbstractTherapeutic drug monitoring (TDM) of busulfan (BU) is currently performed by plasma sampling in patients undergoing hematopoietic stem cell transplantation (HSCT). Saliva samples are considered a noninvasive TDM matrix. Currently, no salivary population pharmacokinetics (PopPKs) model for BU available. This study aimed to develop a PopPK model that can describe the relationship between plasma and saliva kinetics in patients receiving intravenous BU. The performance of the model in predicting the area under the concentration‐time curve at steady state (AUCss) based on saliva samples is evaluated. Sixty‐six patients with HSCT were recruited and administered 0.8 mg/kg BU intravenously. A PopPK model for saliva and plasma was developed using the nonlinear mixed effects model. Bayesian maximum a posteriori (MAP) optimization was used to estimate the model's predictive performance. Plasma and saliva PKs were adequately described with a one‐compartment model and a scaled central compartment. Body surface area correlated positively with both clearance and apparent volume of distribution (Vd), whereas alkaline phosphatase correlated negatively with Vd. Simulations demonstrated that the percentage root mean squared prediction error and lower and upper limits of agreements reduced to 10.02% and −16.96% to 22.86% based on five saliva samples. Saliva can be used as an alternative matrix to plasma in TDM of BU. The AUCsscan be predicted from saliva concentration by Bayesian MAP optimization, which can be used to design personalized dosing for BU.