bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of the striped field mouse’s range expansion on communities of native small mammals
Authors: Tulis Filip , Ševčík Michal , Jánošíková Radoslava , Baláž Ivan , Ambros Michal , Zvaríková Lucia , Horváth Gyözö 
Published: January 2023

AbstractUnderstanding species expansion as an element of the dispersal process is crucial to gaining a better comprehension of the functioning of the populations and the communities. Populations of the same species that are native in one area could be considered nonindigenous, naturalised or invasive somewhere else. The striped field mouse has been expanding its range in south-western Slovakia since 2010, although the origin of the spread has still not been clarified. In light of the striped field mouse’s life history, the recent range expansion is considered to be the expansion of a native species. This study analyses the impact of the striped field mouse's expansion on the native population and small mammal communities and confronts the documented stages of striped field mouse expansion with the stages of invasion biology. Our research replicates the design and compares results from past research of small mammals prior to this expansion at the same three study areas with the same 20 study sites and control sites. Several years after expansion, the striped field mouse has a 100% frequency of occurrence in all study sites and has become the dominant species in two of the study areas. The native community is significantly affected by the striped field mouse’s increasing dominance, specifically: (i) we found a re-ordering of the species rank, mainly in areas with higher dominance, and (ii) an initial positive impact on diversity and evenness during low dominance of the striped field mouse turned markedly negative after crossing the 25% dominance threshold. Results suggested that the variation in the striped field mouse’s dominance is affected by the northern direction of its spread. Our findings show that establishment in a new area, spread and impact on the native community are stages possibly shared by both invasive and native species during their range expansion.
Green synthesis of spermine coated iron nanoparticles and its effect on biochemical properties of Rosmarinus officinalis
Authors: Afrouz Mehdi , Ahmadi-Nouraldinvand Farnaz , Elias Sabry G. , Alebrahim Mohammad Taghi , Tseng Te Ming , Zahedian Hoda 
Published: January 2023

AbstractIn this study, aqueous spinach extract was used for the green synthesis of iron nanoparticles. The surface of iron oxide nanoparticles was coated with spermine. The physicochemical properties of nanoparticles were investigated using UV-Vis, TGA, FTIR, VSM, TEM, and DLS. The results showed that the nanoparticles had a spherical structure. The surface charge of the Fe3O4-NPs increased from −3.2 to 18.42 (mV) after Fe3O4coating by spermine. In order to investigate the effect of nanoparticles on physicochemical properties of rosemary under drought stress conditions, an experiment was carried out in a completely randomized design. The results showed that the amount of antioxidant enzymes and secondary metabolites increased significantly under drought stress. Moreover, the use of spermine-coated iron nanoparticles can be useful in increasing resistance to drought stress in plants by increasing the activity of some antioxidant enzymes and secondary metabolites. The biocompatibility of Nanoparticles in cell suspension was investigated. the ability of Fe3O4-SM NPs to interact with DNA and protect it against DNaseI and ultrasonic waves using agarose gel electrophoresis was studied. The ability of Fe3O4-SM to neutralize the negative charge of DNA and protect it against DNaseΙ and ultrasonic waves was confirmed using an agarose gel electrophoresis assay.
Fmr1-KO mice failure to detect object novelty associates with a post-test decrease of structural and synaptic plasticity upstream of the hippocampus
Authors: Borreca Antonella , De Luca Mariassunta , Ferrante Antonella , Boussadia Zaira , Pignataro Annabella , Martire Alberto , Ammassari-Teule Martine 
Published: January 2023

AbstractMice with deletion of the FMR1 gene show episodic memory impairments and exhibit dendritic spines and synaptic plasticity defects prevalently identified in non-training conditions. Based on evidence that synaptic changes associated with normal or abnormal memory emerge when mice are cognitively challenged, here we examine whether, and how, fragile entorhinal and hippocampal synapses are remodeled when mice succeed or fail to learn. We trained Fmr1 knockout (KO) and wild-type C57BL/6J (WT) mice in the novel object recognition (NOR) paradigm with 1 h or 24 h training-to-test intervals and then assessed whether varying the time between the presentation of similar and different objects modulates NOR performance and plasticity along the entorhinal cortex-hippocampus axis. At the 1 h-interval, KO mice failed to discriminate the novel object, showed a collapse of spines in the lateral entorhinal cortex (LEC), and of long-term potentiation (LTP) in the lateral perforant path (LPP), but a normal increase in hippocampal spines. At the 24 h, they exhibited intact NOR performance, typical LEC and hippocampal spines, and exaggerated LPP-LTP. Our findings reveal that the inability of mice to detect object novelty primarily stands in their impediment to elaborate, and convey to the hippocampus, sensory/perceptive object representations.
Characterizing macular edema in retinitis pigmentosa through a combined structural and microvascular optical coherence tomography investigation
Authors: Arrigo Alessandro , Aragona Emanuela , Perra Cristian , Bianco Lorenzo , Antropoli Alessio , Saladino Andrea , Berni Alessandro , Basile Giulia , Pina Adelaide , Bandello Francesco , Battaglia Parodi Maurizio 
Published: January 2023

AbstractThe aim of the study was to characterize macular edema (ME) in retinitis pigmentosa (RP) by means of quantitative optical coherence tomography (OCT)-based imaging. The study was designed as observational, prospective case series, with 1-year follow-up. All RP patients underwent complete ophthalmologic assessment, including structural OCT, OCT angiography, and microperimetry (MP). The primary outcome was the characterization through quantitative OCT-based imaging of RP eyes complicated by ME. A total of 68 RP patients’ eyes (68 patients) and 68 eyes of 68 healthy controls were recruited. Mean BCVA was 0.14 ± 0.17 LogMAR at baseline and 0.18 ± 0.23 LogMAR at 1-year follow-up (p > 0.05). Thirty-four eyes (17 patients; 25%) showed ME, with a mean ME duration of 8 ± 2 months. Most of the eyes were characterized by recurrent ME. The ME was mainly localized in the inner nuclear layer in all eyes. LogMAR BCVA was similar in all RP eyes, whether with or without ME, although those with ME were associated with higher vessel density values, as well as thicker choroidal layers, than those without ME. In conclusion, the inner retina is closely involved in the pathogenesis of ME. The impairment of retinal-choroidal exchanges and Müller cell disruption might be a major pathogenic factor leading to the onset of ME in RP.
Unraveling the electronic influence and nature of covalent bonding of aryl and alkyl radicals on the B12N12 nanocage cluster
Authors: Berisha Avni 
Published: January 2023

AbstractCarbon nanocage structures such as fullerene, nanotubes, nanocapsules, nanopolyhedra, cones, cubes, and onions have been reported since the discovery of C60, and they offer tremendous promise for investigating materials of low dimensions in an isolated environment. Boron Nitride (BN) nanomaterials such a: nanotubes, nanocapsules, nanoparticles, and clusters have been described in several studies and are predicted to be useful as electronic devices, high heat-resistance semiconductors, nanocables, insulator lubricants, and gas storage materials. The interaction, and electronic of octahedral B12N12 nanocage cluster covalently modified from the attachment of alkyl and aryl radicals were analyzed using Density Functional Theory calculations. The work discusses for the first time to our knowledge the complete investigation of the impact of the grafted aryl and alkyl groups on the electronic, bang gap, and density of states on the B12N12. Furthermore, this is the first complete description of these radicals attaching to a surface of B12N12 nanocage cluster.
Comparison of earthquake-induced shallow landslide susceptibility assessment based on two-category LR and KDE-MLR
Authors: Fan Xinyue , Liu Bin , Luo Jie , Pan Ke , Han Suyue , Zhou Zhongli 
Published: January 2023

AbstractGeological hazards caused by strong earthquakes have caused continuous social and economic losses and destruction of the ecological environment in the hazard area, and are mostly manifested in the areas with frequent occurrence of geological hazards or the clustering of geological hazards. Considering the long-term nature of earthquakes and geological disasters in this region, this paper takes ten earthquake-stricken areas in Wenchuan earthquake zone as examples to collect shallow landslide data in 2010, combined with the spatial location of landslides and other factors. Kernel density estimation (KDE) method is used to analyze the spatial characteristics of shallow landslide. Taking the space of shallow landslide as the characteristic variable and fully considering the regulating factors of earthquake-induced landslide: terrain complexity, distance to river, distance to fault, distance to road, lithology, normalized vegetation difference index (NDVI) and ground peak acceleration (PGA) as independent variables, based on KDE and polynomial logistic regression (MLR), A quantitative model of shallow landslide in the earthquake area is constructed. The results show that: (1) PGA has the greatest impact on landslide in the study area. (2) Compared with the two-category logistic regression (two-category LR) model, the susceptibility map of landslide prediction results based on the KDE-MLR landslide susceptibility prediction model is more consistent with the actual situation. (3) The prediction accuracy of the model validation set is 70.7%, indicating that the landslide susceptibility prediction model based on KDE-MLR can effectively highlight the spatial characteristics of shallow landslides in 10 extreme disaster areas. The research results can provide decision-making basis for shallow landslide warning and post-disaster reconstruction in earthquake-stricken areas.
Numerical investigation of compressible flow around nose cone with Multi-row disk and multi coolant jets
Authors: Iranmanesh Reza , Alizadeh As’ad , Faraji M. , Choubey Gautam 
Published: January 2023

AbstractDue to sever aerodynamic heating, the protection of forebody of scramjet is crucial for hypersonic flight. In present work, a new cooling system is proposed and investigated for the protection of nose cone at hypersonic flight. Computational fluid dynamic is used for the simulation of the lateral and axial coolant jet released from the spike at high-velocity condition. The primary goal is to find optimum jet location for efficient cooling of nose and spike assembly. Influence of two coolant jets (Carbon dioxide and Helium) on the mechanism of cooling system are fully investigated. For simulation, RANS equations are coupled with species transport equation and SST turbulence model. Two different jet configurations (axial disk positions) are investigated to obtain efficient condition for protection of nose cone at hypersonic flight. Our results indicate that the presence of the spike on the nose cone decreases pressure up to 33% on the main body and the shifts the maximum pressure to higher angles because of the deflection of the air stream. Maximum pressure drops about 50% by injection of the coolant disk jet (C2) at angle of 55 deg.
Development and validation of novel automatable assay for cholesterol efflux capacity
Authors: Mutsuda Yume , Miyakoshi Tsunehiro , Horiuchi Yuna , Kameda Takahiro , Tozuka Minoru , Ohkawa Ryunosuke 
Published: January 2023

Abstract
During the past decade, evaluation of high-density lipoprotein (HDL) functionality has been well studied for predicting cardiovascular disease (CVD) risk. Cholesterol efflux capacity (CEC) is the strongest candidate as the biomarker out of various HDL antiatherosclerotic functions. However, CEC has not yet been introduced clinically because of several technical issues, including the use of radioactive materials and differentiated cells in the assay. Previously, our laboratory developed a radioisotope- and cell-free CEC assay called the immobilized liposome-bound gel beads (ILGs) method to replace the conventional method. However, the separation process of the supernatant was not suitable for installation in an automatic analyzer. The present study aims to develop a new method that is easier to operate. We assumed that the use of magnetic beads instead of gel beads would enable the skip of the centrifugal process. First, similar to the ILG method, porous magnetic beads were treated with liposomes containing fluorescently labeled cholesterol. Fluorescence was observed inside the magnetic beads, and almost the same amount of liposomes as in the ILG method was immobilized successfully. These immobilized liposome-bound magnetic beads (ILMs) were available for CEC assay when HDL and apolipoprotein B-100-depleted serum (BDS) were used as cholesterol acceptors. The ILM method showed sufficient basic performance and a good correlation with the ILG method. Furthermore, when the CEC of 15 serum samples from healthy subjects was measured, a good correlation between HDL-cholesterol level and the ILG method was confirmed. Thus, it was confirmed that the ILM method was successfully developed and could be automated.
A large memory window and low power consumption self‐rectifying memristor for electronic synapse
Authors: Li Qingjiang , Yu Shihao , Yang Peng , Wang Qin , Liu Sen 
Published: January 2023

AbstractSelf‐rectifying memristor has no need for selector devices, but possesses the one‐way transmission behaviour and multi‐level non‐volatile memory characteristics, which makes it a promising candidate for electronic synapse. In this letter, the authors propose a novel self‐rectifying memristor based on a Pt/Hf0.5Zr0.5O2/TiN structure. The devices show large memory window (104) and high rectifying ratio (104), which can block the sneak current in a passive crossbar array without any additional hardware overhead. Moreover, the devices demonstrate excellent multi‐level states modulation capability, low power consumption, high endurance and long retention. The final benchmark demonstrates that the proposed Pt/Hf0.5Zr0.5O2/TiN self‐rectifying memristor is a promising candidate for electronic synapse application.
MIMO synthetic aperture sonar: Benefits and limitations
Authors: Hansen Roy Edgar 
Published: January 2023

AbstractThe use of Multiple Input Multiple Output (MIMO) orthogonally coded waveforms sharing the same bandwidth, has the potential to increase area coverage rate in synthetic aperture sonar (SAS). The disadvantage is cross‐talk between the waveforms. In this letter, the benefits and limitations are listed for a best case use of MIMO in SAS. A scheme is developed to emulate a MIMO system with realistic cross‐talk that can be tested on non‐MIMO SAS data. The impact of cross‐talk is evaluated on simulated data and real data collected by a HISAS interfereometric SAS carried by a HUGIN autonomous underwater vehicle. The finding is that the negative impact of cross‐talk on SAS is significant.
A Bibliometric Analysis of Artificial Intelligence Applications in Spine Care
Authors: Zhang Yu , Hu Man , Zhao Wenjie , Liu Xin , Peng Qing , Meng Bo , Yang Sheng , Feng Xinmin , Zhang Liang 
Published: January 2023

Abstract
Background With the rapid development of science and technology, artificial intelligence (AI) has been widely used in the diagnosis and prognosis of various spine diseases. It has been proved that AI has a broad prospect in accurate diagnosis and treatment of spine disorders.
Methods On May 7, 2022, the Web of Science (WOS) Core Collection database was used to identify the documents on the application of AI in the field of spine care. HistCite and VOSviewer were used for citation analysis and visualization mapping.
Results A total of 693 documents were included in the final analysis. The most prolific authors were Karhade A.V. and Schwab J.H. United States was the most productive country. The leading journal was Spine. The most frequently used keyword was spinal. The most prolific institution was Northwestern University in Illinois, USA. Network visualization map showed that United States was the largest network of international cooperation. The keyword “machine learning” had the strongest total link strengths (TLS) and largest number of occurrences. The latest trends suggest that AI for the diagnosis of spine diseases may receive widespread attention in the future.
Conclusions AI has a wide range of application in the field of spine care, and an increasing number of scholars are committed to research on the use of AI in the field of spine care. Bibliometric analysis in the field of AI and spine provides an overall perspective, and the appreciation and research of these influential publications are useful for future research.
A conversation about video game and virtual reality adaptations of canonical plays
Authors: Bushnell Rebecca , Hunter Elizabeth B , Burn Andrew 
Published: January 2023

Abstract
Andrew Burn, Rebecca Bushnell, and Elizabeth B. Hunter discuss ways in which video games and virtual reality can transform canonical plays and Shakespeare in particular. Those transformations can offer insights into the underlying principles and embodied performance of familiar stories. Video games and virtual reality adaptations of canonical theatre can also enrich pedagogy by engaging students in game design and play.
1334 THE OXFORD COGNITIVE COMORBIDITY AND AGEING RESEARCH DATABASE (ORCHARD): DESCRIPTION OF A LARGE ACUTE CARE RESEARCH DATABASE
Authors: Boucher E , Shepperd S , Pendlebury S T 
Published: January 2023

Abstract

Background
Guidelines recommend that all older hospital patients are screened for cognitive comorbidity (i.e. dementia, delirium) and frailty to inform care and target multidisciplinary team resources based mainly on evidence from studies in outpatient or specialty-specific settings. Unselected hospital-wide data are needed to inform guidance and service design and delivery, so we set up the Oxford Cognitive Comorbidity and Ageing Research Database (ORCHARD) using routinely-acquired electronic patient record (EPR) data.

Methods
ORCHARD includes pseudonymised EPR data on all patients &gt;65 years with unplanned admission to one of four general hospitals in Oxfordshire, serving a population of 660,000. Data collected include cognitive screening (mandatory for &gt;70 years) comprising dementia history, delirium diagnosis (Confusion Assessment Method—CAM), and 10-point Abbreviated Mental Test; together with nursing risk assessments, frailty, diagnoses, comorbidities (Charlson index), observations, illness acuity, laboratory tests and brain imaging. Outcomes include length of stay, delayed transfers of care, discharge destination, readmissions, death and dementia through linkage to electronic mental health records.

Results
ORCHARD (2017-2019) includes data from 90,303 consecutive, unselected hospital admissions across all specialties (n=60,535 [67%] inpatient versus n=29,768 [33%] day case; n=73,385 [81%] medical versus n=16,918 [19%] surgical or other). Admissions data were linked to 46,533 unique individuals (n=23,724 [52%] female) with a mean/SD age of 78.3/9.6, Index of Multiple Deprivation Decile of 7.5/2.3 and Charlson Comorbidity of 8.1/9.4 at first admission. Frailty was prevalent, with 15,423 (33%) scoring moderate and 2,471 (5%) high on the Hospital Frailty Risk Score. Complete cognitive screening data are available for 34,416 (67%) unique individuals ≥70 years with inpatient admission.

Conclusion
ORCHARD is a large and rich data resource that will enable studies on the burden and impact of cognitive and physical frailty in-hospital, with relevance to the design and delivery of clinical services, and understanding of healthcare resource use hospital-wide and by specialty.
1200 EFFECT OF BALANCE TRAINING AFTER HIP FRACTURE SURGERY: A SYSTEMATIC REVIEW OF RANDOMISED CONTROLLED STUDIES
Authors: Moniati F , Costa C , Chatzimatthaiou C , Chatzimatthaiou M 
Published: January 2023

Abstract

Introduction
Hip Fracture Surgery (HFS) can result in balance impairment which is associated with an increased risk of falls in the elderly as well as limitations in their mobility. Balanced Training (BT) is a rehabilitation method used aiming to minimize the balance impairments post HFS. BT options include stepping, balance task-specific exercise, standing on one leg, yoga. Our main outcome is to evaluate the effect of BT on the physical functioning of elderly patients post an HFS.

Methods
We conducted a systematic review using the PubMed-Medline, Cochrane Library and Embase databases to locate randomized controlled trials which compared BT with standard care post HFS. The Cochrane’ Library Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement was used as our template for the review.

Results
Overall, nine randomised controlled trials were selected, comprising a total of 712 patients, all aged 65 years of age and older. With regards to the type of BT rehabilitation: four trials used step-ups (n=500), three trials used balance task-specific exercise (n=170) and two studies used standing on one leg (n=42). The BT group demonstrated improvement in physical functioning post HFS compared to the control group (Standardised Mean Difference (SMD) = 0.410). Moreover, all functional parameters which include, lower limb strength, performance task and health related quality of life, were also improved in the BT group.

Conclusion
Evidently, the results demonstrate an improvement of physical functioning by BT post HFS. Furthermore, the positive effects on all functioning parameters were apparent. As a result, the implementation of BT in postoperative rehabilitation programs in elderly patients with hip fractures should be considered.

Reference
[1] Monticone M, Ambrosini E, Brunati R, et al. How balance task-specific training contributes to improving physical function in older subjects undergoing rehabilitation following hip fracture: a randomized controlled trial. Clin Rehabil. 2018;32:340–351.