bluuebunny/crossref_metadata_2025_split huggingface dataset:
Seroprevalence and Evaluation of IgM and NS1 Ag Detection for Early Diagnosis of Dengue Cases in a Tertiary Care Hospital
Authors: Jain Charu , Birhman Nikita , Sinha Swati , Shah Anshdha , Das Shukla , Singh N. P. , Mathur Poonam , Mogha Narendra Singh , Kashyap Divya 
Published: September 2023

Introduction: Dengue fever, a mosquito borne illness, have grown to pose a serious danger to public health systems in developing nations. The Dengue virus (DENV), a member of the Flavivirus genus has four serotypes that cause the disease which range in severity from subclinical infections to severe disease with high morbidity & mortality. This study aims to assess the seroprevalence of dengue fever cases in a tertiary care hospital from East- Delhi region.
Material & Methods: This study was a retrospective observational study conducted in the Department of Microbiology at UCMS & GTBH. The data was collected from laboratory records from a period of Jan 2019 to December 2019.
Results: A total of 1449 clinically suspected cases of dengue were tested for the presence of NS1 antigen and IgM antibodies by capture ELISA. This study showed 32.22% (467/1449) seropositivity of dengue infection. Out of 1272, a total of 456 samples were positive for NS1 Ag ELISA. Whereas, out of 177, a total 11 samples were positive for IgM ELISA.
Observation: The study highlights the importance of early diagnosis and prompt management of dengue cases to prevent severe disease and reduce morbidity and mortality. This underscores the need for increased awareness, early detection, and appropriate management of dengue fever in endemic areas. especially during the peak months of October and November.
Chemotherapy-Induced Rhesus Blood Group Switch in Pleomorphic Sarcoma Patient during Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS) Chemotherapy Protocol, Cycle 5
Authors: Widiyastuti Riani , Limijadi Edward Kurnia Setiawan 
Published: September 2023

Introduction: Changes in Rhesus blood group during cancer treatment are very rare. The Rhesus blood group is a genetic characteristic that usually remains for a lifetime. In this case, a child experiences a Rhesus change during treatment of pleomorphic sarcoma using Non Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS) therapy, which includes surgery, chemotherapy, and radiotherapy. The side effects of chemotherapy on red blood cells may cause changes to the Rhesus antigen.
Case: A 17-year-old boy underwent chemotherapy with a history of blood transfusion for 9 times using A Rhesus negative blood. However, the latest crossmatch examination showed his blood group was weak A Rhesus positive. The patient was then given a transfusion of A Rhesus positive blood which was considered compatible. Before transfusion, the patient was given a corticosteroid injection premedication and monitored for 2 weeks.
Conclusion: Pleomorphic sarcoma treatment, such as chemotherapy, has the potential to affect the expression of Rhesus antigen. Alkylating agents can replace hydrogen atoms with alkyl radicals, which can modify chemical groups and change the normal sequence of the polypeptide chain which can alter the expression of the Rhesus antigen.
Vaccine and Adjuvant Mediated Autoimmunity
Authors: Shnawa Ibrahim M. S. 
Published: September 2023

The macrophage, natural killer cells, B and T cells are the outstanding formed elements of human immune system. In normal immune homeostatic state these cells in a way or other recognize the host body components as self via the immune surveillance mechanisms. Though when there was a shift in immune homeostasis due to chronic induction by; i - environmental stimulus, ii –interplay of predisposing genetic elements, iii-family history, iv – bystander pathologic inflammatory system .Immune cells becomes prone to recognize the impart self or self as a non-self with subsequent induction of autoimmune diseases. The present opinion paper was aimed at vaccine and adjuvant mediated autoimmune diseases. Timelines for vaccine and adjuvant induced autoimmunity were made. Different human approved vaccines induce different autoimmune disease, more than on vaccine may induce same autoimmune disease. Shoenfeld Syndrome, the adjuvant induce autoimmune/ inflammatory syndrome. Under the umbrella of this syndrome five conditions grouped as; i – Postvaccination with an adjuvanated vaccine, ii – macrophagic myofasciitis, iii – sick building disease condition iv – Gulf war disease condition and v – siliconosis. Protocol for the practical evaluation of these diseases was suggested. Understanding Shoenfeld Syndrome is crucial for producing vaccines with a safer side effect profile.
Screening of Antimicrobial Resistance in Bacterial Isolates from Red Sea Coast in Jeddah, Saudi Arabia
Authors: Alsalmi Mohannad A. , Altayb Hisham N. 
Published: September 2023

Objectives: Antibiotic resistance is a major public health problem worldwide. There is little data on the incidence, sources, and importance of antibiotic-resistant bacteria on the Red Sea coast of Jeddah. This study aims to identify drug-resistant microbes found on the Red Sea coast in Jeddah and to screen their resistance profile against different antibiotics.
Methodology: Forty-eight samples were obtained from different locations on the Red Sea coast in Jeddah. Antimicrobial susceptibility tests were performed against the following antibiotic discs (Oxoid): cefotaxime (CTX) (30g); meropenem (MEM) (10g); gentamicin (CN) (10g) and chloramphenicol (C) (30g).
Results: The isolates showed resistance to Gentamicin 10 mcg (39.47%; 15/38), Cefotaxime 30 mcg (18.42%; 7/38), Meropenem 10 mcg (0%; 0/38) and Chloramphenicol 30 mcg (5.26%; 2/38).
Conclusion: From this study there is a high resistance rate to cefotaxime, chloramphenicol and gentamicin 39%. This research has substantiated the existence of a substantial prevalence of resistance to various microbial agents within our environment, specifically within the Red Sea in Jeddah. We propose conducting future studies across diverse geographic regions, utilizing extensive sample sizes, to gain a deeper insight into the potential impact of environmental factors and pollution on the propagation of drug-resistant bacteria. Additionally, the identification of these bacterial strains is essential for understanding their characteristics and devising strategies to combat them effectively, thereby assisting in curtailing their proliferation.
Utilizing Big Data Analytics and Business Intelligence for Improved Decision-Making at Leading Fortune Company
Authors: Olaniyi Oluwaseun Oladeji , Abalaka Anthony Idoko , Olabanji Samuel Oladiipo 
Published: September 2023

The present study evaluates Walmart’s existing big data analytics with business intelligence techniques, accentuating their strengths and weaknesses, and suggests improvements for implementation and maintenance through the literature review of the scholarly journals addressing similar topics. Big data analytics is receiving loads of attention globally in the business environment within every sector of the economy. Incorporating the job plan as an additional input component in their models would be beneficial for Walmart to improve the precision and appropriateness of their data analysis and decision-making procedures. Walmart is a company that heavily invests in utilizing big data to improve its operations; this includes optimizing in-store experiences and predicting product trends. Scholarly articles emphasize the importance of advanced data analytics tools like MapReduce and Apache Spark for effective big data strategies. Social media content influences engagement and sentiment. Social network data aids sales forecasting but presents challenges. Big data analytics with business intelligence enhances performance and decision-making. Walmart's success in big data analytics relies on a data-driven culture but faces security challenges. Many Fortune 1000 companies adopt innovative solutions to improve performance and customer experiences but require significant resources. Embracing big data analytics with business intelligence remains a compelling investment for sustaining a competitive edge. Walmart's success in big data analytics is due to a data-driven culture and advanced infrastructure, including the Data Café.
Control of Torque Ripple and Rotor Position for SRM (8/6‐4 Phases) Using an Optimization‐Based Model Predictive Torque Control
Authors: Pawar Jayshree Dasharath , Nikose Mangesh D. 
Published: January 2025

ABSTRACTMost electric cars and wind turbines employ switched reluctance motors (SRM), but it has some disadvantages, namely high torque ripple because of its power supply mode and multiphase communication. Model predictive torque control (MPTC) with sailfish optimization (SFO) method is proposed to reduce torque ripple of SRM using torque sharing function (TSF). To develop an efficient torque ripple algorithm, the flux‐linkage characteristic curves are first acquired at protected rotor trial and create an accurate SRM model. It predicts future operation for drive system in SRM architecture. Second, the SFO algorithm is employed to enhance TSF parameters also to minimize the torque value of SRM. Then, the TSF‐based MPTC method is developed to avoid problem like conversion of frequency produced by controller. Finally, atom search optimization (ASO) is used to adjust sensor for correct rotor position of the SRM. To verify the performance of the proposed method, MPTC‐SFO is compared with direct instantaneous torque control (DITC) method. Proposed MPTC‐SFO method attained more efficient result of 12.79% reduced torque ripple than DITC.
Integration of Cobalt Ferromagnetic Control Gates for Electrical and Magnetic Manipulation of Semiconductor Quantum Dots
Authors: Bersano Fabio , Aldeghi Michele , Martinolli Niccolò , Boureau Victor , Aboud Thibault , Ghini Michele , Scarlino Pasquale , Salis Gian , Ionescu Adrian M. 
Published: January 2025

AbstractThe rise of electron spin qubit architectures for quantum computing processors has led to a strong interest in designing and integrating ferromagnets to induce stray magnetic fields for electron dipole spin resonance (EDSR). The integration of nanomagnets imposes, however, strict layout and processing constraints, challenging the arrangement of different gating layers and the control of neighboring qubit frequencies. This work reports a successful integration of nano‐sized cobalt control gates into a multi‐gate fully‐depleted silicon‐on‐insulator (FDSOI) nanowire with nanometer‐scale dot‐to‐magnet pitch, simultaneously exploiting electrical and ferromagnetic properties of the gate stack at nanoscale. The electrical characterization of the multi‐gate nanowire exhibits full field effect functionality of all ferromagnetic gates from room temperature to 10 mK, proving quantum dot formation when ferromagnets are operated as barrier gates. The front‐end‐of‐line (FEOL) compatible integration of cobalt is examined by energy dispersive X‐ray spectroscopy and high/low frequency capacitance characterization, confirming the quality of interfaces and control over material diffusion. Insights into the magnetic properties of thin films and patterned control‐gates are provided by vibrating sample magnetometry and electron holography measurements. Micromagnetic simulations anticipate that this structure fulfills the requirements for EDSR driving for magnetic fields higher than 1 T, where a homogeneous magnetization along the hard magnetic axis of the Co gates is expected. The FDSOI architecture showcased in this study provides a scalable alternative to micromagnets deposited in the back‐end‐of‐line (BEOL) and middle‐of‐line (MOL) processes, while bringing technological insights for the FEOL‐compatible integration of Co nanostructures in spin qubit devices.
Bioprinted Fibroblast Mediated Heterogeneous Tumor Microenvironment for Studying Tumor‐Stroma Interaction and Drug Screening
Authors: Chen You , Xue Yifan , Yan Cong , Jin Jinlong , Liu Yadong , Li Jing , Han Shuai , Liu Jie 
Published: January 2025

AbstractCancer‐associated fibroblasts (CAFs) are crucial stromal cells in the tumor microenvironment, affecting cancer growth, angiogenesis, and matrix remodeling. Developing an effective in vitro tumor model that accurately recapitulates the dynamic interplay between tumor and stromal cells remains a challenge. In this study, a 3D bioprinted fibroblast ‐ mediated heterogeneous breast tumor model was created, with tumor cells and fibroblasts in a bionic matrix. The impact of transforming growth factor‐β （TGF‐β） on the dynamic transformation of normal fibroblasts into CAFs and its subsequent influence on tumor cells is further investigated. These findings reveales a profound correlation between CAFs and several critical biological processes, including epithelial‐mesenchymal transition (EMT), extracellular matrix (ECM) remodeling, gene expression profiles, and tumor progression. Furthermore, tumor models incorporating CAFs exhibits reduced drug sensitivity compared to models containing tumor cells alone or models co‐cultured with normal fibroblasts. These results underscore the potential of the in vitro fibroblast‐mediated heterogeneous tumor model to simulate real‐life physiological conditions, thereby offering a more effective drug screening platform for elucidating tumor pathogenesis and facilitating drug design prior to animal and clinical trials. This model's establishment promotes the understanding of tumor‐stromal interactions and their therapeutic implications.
Solvothermal Template‐Induced Hierarchical Porosity in Covalent Organic Frameworks: A Pathway to Enhanced Diffusivity
Authors: Heck Fabian , Grunenberg Lars , Schnabel Nadine , Heilmaier Amelie , Sottmann Thomas , Yao Liang , Lotsch Bettina V. 
Published: January 2025

AbstractThe rapid advancement of covalent organic frameworks (COFs) in recent years has firmly established them as a new class of molecularly precise and highly tuneable porous materials. However, compared to other porous materials, such as zeolites and metal‐organic frameworks, the successful integration of hierarchical porosity into COFs remains largely unexplored. The challenge lies in identifying appropriate synthetic methods to introduce secondary pores without compromising the intrinsic structural porosity of COFs. In this study, a template‐induced synthetic methodology is realized to facilitate the construction of hierarchically porous COFs (hCOFs). This novel approach utilizes commercially available zinc oxide nanoparticles as a hard template, enabling to increase the total pore volume of a series of β‐ketoenamine‐linked COFs as well as an imine‐based COF while preserving their surface areas. In addition to transmission electron microscopy and gas adsorption analyses, small‐angle X‐ray scattering and pulsed field gradient nuclear magnetic resonance techniques are employed to investigate the hierarchical porosity and diffusivity of guest molecules within hCOFs. This study demonstrates that the hierarchically porous nature of hCOFs significantly reduces diffusion limitations, thus leading to simultaneous enhancements in adsorption capacity, diffusivity, and catalytic performance.
A Tribo/Piezoelectric Nanogenerator Based on Bio‐MOFs for Energy Harvesting and Antibacterial Wearable Device
Authors: Wang Yuqi , Su Peipei , Lin Zhang , Li Xiaolin , Chen Kangbo , Ye Tingting , Li Yaping , Zou Yang , Wang Wei 
Published: January 2025

AbstractNew types of metal–organic framework (MOF) materials have great potential in solving the current global dilemma on energy, environment, and medical care. Herein, based on two kinds of biomolecule‐MOFs (Bio‐MOFs) with favorable biocompatibility and degradation‐reconstruction characteristics, we have established a self‐powered muti‐functional device to achieve an efficient and broad‐spectrum environmental energy collection and biomedical applications. Combining Zn(II) and carnosine‐based Zn‐Car_MOF possessing a high piezoelectric response (d33 = 11.17 pm V−1) with patterned polydimethylsiloxane (PDMS) film, a tribo‐piezoelectric hybrid nanogenerator (TPHG) is constructed with a synergy output of triboelectric and piezoelectric effects. The Zn‐Car_TPHG demonstrates a high output performance (131 V at 100 kPa) and a wide range of pressure response (1 Pa–100 kPa), possessing applications in environmental energy collection and biomedical sensors. To expand the application of the wearable device, a conductive hexagonal prism MOF (Cu3(2,3,6,7,10,11‐hexahydroxytriphenylene)2 (Cu‐HHTP)) is synthesized and employed to load thymol (Thy). Cooperating with Zn‐Car_TPHG, the resulting Cu‐HHTP/Thy can achieve an efficient self‐powered ROS (singlet oxygen (1O2) and hydroxyl radical (·OH)) generation and drug synergistic broad‐spectrum sterilization effect (efficiency ≥ 98%). In a word, the flexible wearable device based on the muti‐functional Bio‐MOFs is sustainable and environmentally friendly, possessing wide application potential in fields of environmental energy collection, biosensors, and self‐powered antibacterial.
Dual‐Gate Organic Electrochemical Transistors Based on Laser‐Scribed Graphene for Detecting Dopamine and Glutamate
Authors: Yao Yao , Alimardani Farzam , Ren Ping , Dong Jingyan , Lee SungHo , Lee Yuan‐Shin , Wang Yi 
Published: January 2025

AbstractOrganic electrochemical transistors (OECTs) are gaining significant attention due to their high sensitivity, customizability, ease of integration, and low‐cost manufacturing. In this paper, we design and develop a flexible dual‐gate OECT based on laser‐scribed graphene (LSG) with modified OECT gates for the detection of dopamine and glutamate, two critical neurotransmitters (NTs). The developed OECTs are fully carbon‐based and environmentally friendly. By modifying the gates of OECTs with biopolymer chitosan and L‐Glutamate oxidase enzyme, highly selective and sensitive measurements are successfully achieved with detection limits of 5 nm for dopamine and 1 µm for glutamate, respectively. The modified dual‐gate shows no interference between the detections of two neurotransmitters, making it a promising tool for customized multi‐neurotransmitter analysis. The results demonstrate the potential of LSG‐based OECTs in customizable biosensing applications, offering a flexible, cost‐effective platform for biomedical disorder diagnostics.
Polypropylene Mesh Coated with Dual Cross‐Linked Hyaluronic Acid/Polyvinyl Alcohol Composite Hydrogel with Antiadhesion and Angiogenesis Properties for Abdominal Wall Repair
Authors: Wei Dandan , Jiao Guanhua , Tao Yinghua , Yang Liuxin , Liu Tao , Jing Fengya , Zhang Tianzhu 
Published: January 2025

AbstractDevelopment of an antiadhesion polypropylene (PP) mesh in hernia repair is a recognized need because its efficacy is limited by severe abdominal adhesions. The porous structure of PP mesh can facilitate the integration between prosthetic material and abdominal tissue and promote the repair of abdominal wall defect. Herein, an antiadhesion composite hydrogel coating composed of polyvinyl alcohol (PVA) and hyaluronic acid methacrylate (HAMA) is fabricated on the surface of PP mesh through ultraviolet photopolymerization combined with freezing–thawing method. The resulted composite hydrogel coated PP mesh retain 43.33% of the pore structure by this way. In vitro tests proved the as‐prepared PP mesh exhibit excellent hydrophilicity and biocompatibility. Meanwhile, the hydrogel coating shows good stability on the surface of PP mesh in phosphate buffered saline medium. After implantation in a rat abdominal wall defect model, the modified PP mesh effectively prevents the formation of adhesion by reducing inflammatory response and suppressing excessive deposition of collagen fiber. Immunohistochemical staining results demonstrate that the modified PP mesh can not only decrease the expression of IL‐6, TNF‐α, and CD68 but also promote the expression of CD31. Thus, this type of PP mesh with preventing postoperative adhesions and improving angiogenesis may be a promising clinical prosthetic material.
Brønsted Acid‐Catalyzed Enantioselective and Para‐Selective Addition of Phenols to 1‐Alkynylnaphth‐2‐Ols
Authors: Dahiya Anjali , Dhara Kalyan , Garo Jordan , Gicquiaud Julien , Karnat Alexandre , Berlande Murielle , Hermange Philippe , Sotiropoulos Jean‐Marc , Toullec Patrick Y. 
Published: January 2025

AbstractA chiral Brønsted acid‐catalyzed synthesis of axially chiral alkenes was developed via an enantioselective and para‐selective Friedel–Crafts reaction between phenols and 1‐alkynylnaphth‐2‐ols. This methodology features an efficient hydroarylation with high functional group tolerance, complete para‐selectivity, excellent yields (up to 99%), and enantioselectivities (up to 94% ee) in the presence of a N‐triflylphosphoramide catalyst. DFT calculations were performed to investigate para‐selectivity and results indicate that both kinetics and thermodynamics parameters are more favorable compared to ortho‐selectivity.
Effect of Sulfates on the Reaction Pathway Over CeO2‐Based Catalyst for NH3‐SCR
Authors: Song Zhongxian , Guo Ruihua , Zhang Mengru , Liu Hongpan , Mao Yanli , Huang Zhenzhen , Gu Deming , Kang Haiyan , Zhang Jinhui , Zhang Xuejun 
Published: January 2025

ABSTRACTCeO2‐H2SO4 (C‐S), CeO2‐TiO2 (C‐T), and CeO2‐TiO2‐H2SO3 (C‐T‐S) were used for the selective catalytic reduction of NO with NH3 (NH3‐SCR). Nearly 100% NOx conversion of C‐T‐S was achieved at 250°C–450°C. When the concentration of Ce2(SO4)3 was excessively high, it causes tightly binding with Ce3+ ions in CeO2, prevents some Ce3+ ions from effectively participating in redox reactions, and results in the inferior SCR activity. Consequently, C‐T‐S possessed the superior catalytic performance due to the optimal content of sulfates. Furthermore, the presence of NO2 facilitated the rapid SCR reaction on C‐T‐S, thereby further enhancing the catalytic activity. Additionally, the formation of Ce2(SO4)3 on C‐T‐S could increase the number of acid sites, particularly Brönsted acid sites, resulting in the improvement of SCR performance. C‐S, C‐T, and C‐T‐S mainly followed the Langmuir–Hinshelwood (L–H).
Nickel‐Doped h‐MoO3 Cathodes: A High‐Performance Material for Aluminum‐Ion Batteries
Authors: Almodóvar Paloma , Álvarez‐Serrano Inmaculada , Llorente Irene , López María Luisa , Chacón Joaquín , Díaz‐Guerra Carlos 
Published: January 2025

ABSTRACTThis study introduces a novel method for the effective doping of hexagonal molybdenum trioxide (h‐MoO3) microstructures with different contents of nickel, significantly enhancing its electrochemical performance in aluminum‐ion batteries (AIBs). Ni doping does not alter the high crystallinity and phase purity of the pristine oxide but modifies its defective structure and electronic properties. Electrochemical tests, including cyclic voltammograms and charge–discharge cycling, showed improvements in capacity and stability for Ni‐doped samples as compared with undoped ones. Moreover, the incorporation of Ni was found to enhance the structural integrity and electrochemical stability of h‐MoO3, preventing the formation of intermediate phases during cycling and reducing resistance at the electrode–electrolyte interface. The existence of an optimal Ni doping of about 1 at% is evidenced. Samples with this Ni content attain a stabilized specific capacity of 230 mAh g−1 over 100 cycles, doubling that reported in previous works for h‐MoO3 composites with carbon nanotubes. Nickel‐doped h‐MoO3 shows exciting potential for advanced AIB applications, paving the way for further energy storage technology advancements.