bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multi-Objective Linear Optimization on Immediate Distributing poultry with Time Windows: Modellings and Applications
Authors: Wang Jinfeng , Huang Shuaihui , Chen Hao , Tang Jiayan , Fu Haoyang , Wang Wenzhong 
Published: August 2023

Abstract
The informatization popularization in livestock and poultry breeding industry has become the mainstream development trend. The optimal scheduling of poultry is mainly divided into two categories: the optimal design of resource allocation and the maximum carrying capacity of existing equipment. This article proposes a multi-objective optimization model which can reduce the cost of transports, improve the efficiency of transferring, save manpower costs, and decrease the death rate of poultries.
Two versions of the model are proposed from different views. One is a sophisticated, elaborated and ideal model, which considers all conditions. It can obtain a best solution with high computational complexity.The other one is a simplified and concise version which can be applied to the real production more easily. It can obtain an acceptable solution with high speed. The time window method based on multi-objective mixed integer is introduced. An optimization method based on adaptive algorithm is adopted. The optimization model decomposed into several sub-models to reduce the data scale and obtain the sub-optimal feasible scheme.
Experiments are implemented for two situations. The latter optimization scheme is more suitable and easy for the actual production and operation environment and the result is simple. The former optimization scheme is conducive to the further study of the optimization scheme and easy to expand the application scenes. The model and the two solutions proposed in this article not only solve the problem of optimal scheduling of poultry distribution, but also have strong stability and practical application value. The code and simulated data are available at: https://github.com/Hu-s-h/Poultry-Model.
Nature of active sites at Pt/CeO2 interfaces for the water-gas-shift reaction
Authors: Boscoboinik Jorge , Li Gengnan , Zakharov Dmitri , Hu Tianhao , Yu Youngseok , Waluyo Iradwikanari , Hunt Adrian , Head Ashley 
Published: August 2023

Abstract

Understanding the atomistic structure of the active site during catalytic reactions is of paramount importance in both fundamental studies and practical applications, but such studies are challenging due to the complexity of heterogeneous systems. Using Pt/CeO2 as an example, we reveal the dynamic nature of active sites during the water-gas-shift reaction (WGSR) by combining multiple in situ characterization tools to study well-defined CeO2 nanoshapes with different exposed facets. We show that metallic Pt is present on the CeO2(111) surfaces, while oxidized Pt species are dominant on CeO2(110) and (100) surfaces after O2–H2 pretreatment. The different concentrations of interfacial Ptδ+ – O – Ce4+ moieties at Pt/CeO2 interfaces are responsible for the rank of catalytic performance of Pt/CeO2 catalysts: Pt/CeO2-rod > Pt/CeO2-cube > Pt/CeO2-oct. For all the catalysts, metallic Pt is formed during the WGSR, leading to the transformation of the active sites to Pt0 – Ov – Ce3+ and interface reconstruction. These findings shed light on the nature of the active site for the WGSR on Pt/CeO2 and highlight the importance of combining complementary in situ techniques for establishing structure-performance relationships.
“Togetherness” of superior mesenteric vein and ileocolic artery: how 3D CT based understanding of unusual anatomy influences the approach to D3 lymph node dissection
Authors: Efetov Sergey , Zubayraeva Albina , Rychkova Arina , Zubayraeva Amina 
Published: August 2023

Abstract

Purpose: There are several uncertainties on proper borders for D3-lymph node dissection (D3LND) in right colon cancer. To standardize the approach to lymph node dissection, superior mesenteric artery (SMA) or superior mesenteric vein (SMV) were suggested as anatomical landmarks. There is still no consensus, if SMA or SMV should be accepted as a surgical trunk for D3LND. Moreover, spatial vascular anatomy of ileocolic vessels in relation to SMV and SMA should be considered to reach complete lymph node dissection.
Methods: A 62-year-old female was presented with hepatic flexure colon cancer. On computed tomography (CT) scan it was shown that SMA was laterally to the left from SMV. SMV in its distal part was passing along ileocolic artery in caudal direction. To completely excise the lymph nodes, SMA was considered as a landmark to remove the mesocolic tissue between SMA and SMV.
Results: As a result, 25 lymph nodes (LNs) along SMA and 8 lymph nodes along SMV were harvested. There were no metastatic lymph nodes found along SMA and SMV.
Conclusion: This case demonstrates the importance of spatial anatomy consideration in defining landmarks to perform complete lymph node dissection.
The so-called arteriovenous flap can be considered as an important area of mesocolic root, which may contain lymph nodes and should be excised to perform complete lymph node dissection.
A Novel Non-Parametric Data Envelopment Analysis (DEA) Approach in Sub-basin Prioritization for Watershed Management in the Kumari River Basin, India
Authors: Jaman Md. Hasanur , Roy Subha , Das Souvik , Chatterjee Jaya , Sengupta Somasis 
Published: August 2023

Abstract

In a country like India where economy of the area is predominantly based on agriculture, a maximum proportion of people are dependent upon cultivation and therefore the soil health plays as engine to the enhancement of the agricultural productivity. Continuous soil erosion leads to the loss of top soil that has been responsible for systematic degradation of the soil and natural environment with time. In this context, watersheds, as a scale of natural boundaries, can be applied to implement a comprehensive soil management plan for the systematic conservation of the soil resource. In this situation, watershed management has emerged as a new approach that is based on the interrelationships between landuse, soil, and water and the process of planning and management of land, soil, water resources as well as the biotic resources. It is well accepted that the measurement of actual soil loss is not possible, so different proxies and prediction-based models of erosion susceptibility have been widely used for assessing the soil loss. Sub-basin prioritization with respect to erosion susceptibility, therefore, has become increasingly popular in the last few decades as this helps in optimal distribution of resources for management. In a country like India, where the availability of resources is limited, optimal distribution of resources becomes a challenge. Erosion is a complex problem wherein a large number of factors play an important role in influencing this process. Therefore, Multi-Criteria Decision Making (MCDM) techniques are now becoming more popular in this aspect. However, there are a myriad parametric and non-parametric MCDM models have been used to measure sub-basin soil erosion susceptibility. In terms of the non-parametric techniques, the most common are composite ranks. But the linear programming algorithm-based Data Envelopment Analysis (DEA) technique takes into account one possible optimal solution based on a number of solutions. Although the DEA technique is extremely popular in the domain of business management, this approach has never been used in the domain of resource and hazard management. So, this study is a novel approach in this field where the DEA technique has been introduced for sub-basin prioritization. The approach that has been included for this study is one of profit maximization i.e., the maximum efficiency of the sub-watersheds in terms of erosion susceptibility. So, the basins which are characterized by higher DEA scores are experiencing greater risk of erosion (and hence require prioritization). In the Kumari Basin, the sub watershed wise erosion susceptibility does not show any spatial pattern. The most erosion susceptible sub-watersheds which require the greatest priority for the right bank watersheds as compare to the left bank tributary include DMDR041R013, DMDR041R002, DMDR041R009, DMDR041R016 and DMDR041R014.
Long-short term memory prediction of user’s locomotion in Virtual Reality
Authors: Mayor Jesus , Calleja Pablo , Fuentes Felix , Umetani Nobuyuki 
Published: August 2023

Abstract
Virtual reality has some well-known limitations when the user walks naturally. A user experiencing virtual reality may collide with the limits of the physical workspace. To solve this, there exist techniques, such as the redirected walking methods, that try to trick the human brain to avoid these limits. However, these methods require good predictions of where users want to go in the future. On the other hand, Deep learning is helping in so many areas to make accurate predictions. Specifically, Long short-term memory obtained promising results in this virtual reality prediction task giving us clues to continue researching in this line. This manuscript presents an experiment carried out with 44 participants collecting positional data. These data have been used to test different existing prediction algorithms. In addition, a way to improve the previous results obtained with deep learning is presented. These results are achieved with the use of rotation quaternions and various positional data in three dimensions. The authors strongly believe that there is still much room for improvement in this research area.
Minimally invasive plate osteosynthesis for distal radius fractures using a 3-point positioning technique
Authors: Ye Youyou , Shen Zhaoqing , Wu Chunling , Lin Yanbin 
Published: August 2023

Abstract

In this study, we perform a retrospective analysis of the mid-term clinical results of distal radius fractures treated with the 3-point positioning technique using a minimally invasive plate osteosynthesis (MIPO) while preserving the pronator quadratus (PQ). The 3-point positioning technique was applied: the Kirschner wire was inserted after fluoroscopy and was correctly adjusted the position of the plate above the PQ. With the aid of Kirschner wires positioning the PQ stripping was performed only once, and the plate then placed in a correct and satisfactory position. Operation time, incision length, wrist pain score, upper extremity function DASH score, wrist Gartland-Werley score, wrist grip strength, and range of motion (ROM) were among the quantitative variables recorded. Qualitative variables including AO fracture classification, intraoperative and postoperative complications were evaluated. Twenty patients were enrolled in the study with an average follow-up of 6.8 ± 0.76 months. Of these, 8 males and 12 females were enrolled. the DASH score for the upper limb was 4.7 ± 1.3, and the Gartland-Werley score for wrist function was 11.9 ± 2.5 at the last follow-up. Mean flexion was 97.3%, extension was 97.1%, pronation was 98.8%, supination was 98.6%, and grip strength was 86.1% compared to contralateral values. No unfavorable intraoperative or postoperative complications occurred. The 3-point positioning technique can greatly minimize the damage to the PQ muscle and is a safe and effective method for MIPO for distal radius fractures.
A novelty of the influence of impedance property on graphite filled hybrid epoxy composites in antibacterial and antifouling performance in the marine environment
Authors: M. SABU , E. Bementa , Y. Jaya Vinse Ruban , P. Raja , R. Senthil Kumar 
Published: August 2023

Abstract

Marine resources and industry have emerged as one of the most crucial cornerstones of global economic development. Be that as it may, erosion of materials is dependably the most difficult issue to the foundation and gear served in the marine environment. Scientists have tracked down that microbiologically influenced corrosion (MIC) and marine bio-fouling are two fundamental components of marine erosions because of the muddled marine environment and marine creatures. Herein, we firstly synthesized a novelty composites of graphite incorporated epoxy composites and took thermomechanical tests like differential filtering calorimetry (DSC), and tensile test for the strength of the materials. The outcomes showed a conspicuous improvement of mechanical properties in the adjusted resin system. Besides, the developed graphite-epoxy nanocomposite was gone through the electrical conductivity test for the movement of electron into it. Marine field tests revealed that graphite embedded epoxy nanocomposites showed excellent antifouling execution inside ninety days. In a nutshell, the graphite-epoxy nanocomposites have extraordinary mechanical properties and brilliant impedance properties, showing high potential in the marine antifouling field.
Wolbachia improves the performance of an invasive fly after a diet shift
Authors: Deconninck Gwenaëlle , Larges Jordy , Henri Hélène , Beaugeard Laureen , Foray Vincent , Pincebourde Sylvain 
Published: August 2023

Abstract
Polyphagy is an adaptative strategy allowing species to develop and survive on multiple diets. Phytophagous insects can be exposed to sub-optimal resources, as host plants vary in nutritional quality. Some insects may rely on symbiotic bacteria to better utilize less favorable substrates. The invasive fruit fly Drosophila suzukii is a highly successful pest worldwide. The use of ripening and ripe fruits, a niche neglected by other drosophilids, and its polyphagy may have contributed to its global spread. The role of D. suzukii’s Wolbachia strain (wSuz) remains unconfirmed, although a mutualistic role in dealing with abiotic stress has been hypothesized. In some insect species, Wolbachia acts as a nutritional mutualist. This study explored the role of wSuz in D. suzukii adaptation to fluctuating diet regimes. To simulate a diet shift, we used Wolbachia-infected and uninfected flies, maintained on a corn-based (low-starch) or a grape-based (high-starch) diet for at least 10 generations. Then, we placed individuals from each line on one or the other diet for 30 days. The effects of Wolbachia and the diet treatments were assessed by quantifying female fecundity, egg-to-adult development time and survival, and offspring mass. The presence of Wolbachia positively affected female fecundity and offspring mass after a diet shift. Wolbachia also increased survival during larval development regardless of the diet, supporting its mutualistic role. Our results underline the role of wSuz on D. suzukii diet tolerance and performance. A better understanding of the role of symbionts in invasive species could help to improve management strategies.
Unique genetic and risk-factor profiles in multimorbidity clusters of depression-related disease trajectories from a study of 1.2 million subjects
Authors: Juhasz Gabriella , Gezsi Andras , Auwera Sandra Van der , Mäkinen Hannu , Eszlari Nora , Hullam Gabor , Nagy Tamas , Bonk Sarah , González-Colom Ruben , Gonda Xenia , Garvert Linda , Paajanen Teemu , Gal Zsofia , Kirchner Kevin , Millinghofer Andras , Schmidt Carsten , Bolgar Bene , Roca Josep , Cano Isaac , Kuokkanen Mikko , Antal Peter 
Published: August 2023

Abstract

The heterogeneity and complexity of symptom presentation, comorbidities and genetic factors pose challenges to the identification of biological mechanisms underlying complex diseases. Current approaches used to identify biological subtypes of major depressive disorder (MDD) mainly focus on clinical characteristics that cannot be linked to specific biological models. Here, we examined multimorbidities to identify MDD subtypes with distinct genetic and environmental factors. We leveraged dynamic Bayesian network approaches to determine a minimal set of multimorbidities relevant to MDD and identified seven clusters of disease-burden trajectories throughout the lifespan among 1.2 million participants from transnational cohorts. The clusters had clear protective- and risk-factor profiles as well as age-specific clinical courses mainly driven by inflammatory processes, and a comprehensive map of heritability and genetic correlations among these clusters was revealed. Our results can guide the development of personalized treatments for MDD based on the unique genetic, clinical and modifiable risk-factor profiles of patients.
Intention to Use Patient Portal and Its Predictors Among Diabetic Patients Enrolled in Referral Hospitals, Amhara Regional State, Northwest Ethiopia, 2023: Utaut2 Modeling
Authors: Abebe Aschale Wubete , Tilahun Binyam Chakilu , Derese Masresha , Mekonnen Zeleke Abebaw 
Published: August 2023

Abstract

Background Patient portal technology is increasingly utilized in the health care system for diabetes management, as means of communication and information-sharing tools and it has the potential to improve access, quality, and outcomes for diabetic patients. However, its adaption is relatively low and patients’ intention towards patient portal is unknown. This study aims to fill this gap by determining the intention to use the patient portal and its predictors among diabetic patients in Ethiopia. Method An institution-based cross-sectional study was conducted on 1078 diabetes patients from April 3 to May 8 in eight referral hospitals Amhara region, Ethiopia 2023. Sample was proportionally allocated for each hospital and participants were selected by using a systematic random sampling method. The data were collected in the same period in all hospitals by using interviewer-administered questioner; by kobo collect mobile app. Descriptive statistics were done using SPSS version 26. The degree of association between exogenous and endogenous variables was assessed and validated using structural equation modeling by AMOS version 21. Result A total of 1037 (96.2% response rate) diabetic patients participated in the study. Of them 407(39.25%), 95% CI: [36.4–42.2] were found to have an intention to use patient portal. Digital literacy (β = 0.312, 95% CI: [0.154–0.465], p < 0.01) performance expectancy (β = 0.303, 95% CI: [0.185–0.420], p < 0.01) effort expectancy (β = 0.25 95% CI: [0.131–0.392], p < 0.01) facilitating condition (β = 0.22 95% CI: [0.081–0.36], p < 0.01) and habit (β = 0.111 95% CI: [-0.009-0.227], p < 0.05) were significantly associated with intention to use patient portal. Effort expectancy and facilitating condition were positively moderated by gender. Conclusion This study found that diabetes patient’s intention to use patient portal was low. Intervention in digital literacy, performance expectancy, effort expectancy, facilitating conditions and habit are needed to improve diabetic patient’s intention to use the patient portal.
Evaluation of the Influence of Interest Rates on Private Domestic Investment in Nigeria
Authors: Michael Eze Onyebuchi , Nnabu Eze Benard 
Published: August 2023

Abstract
The study evaluated the effect of interest rates on private domestic investment in Nigeria from 1986 to 2019. The paper employed the Auto-Regressive Distributed Lag model in the analysis. To achieve robust results, the study conducted a structural break test in the time series and co-integration analysis. The main findings of the study were that interest rates had a negative and significant effect on private domestic investment in both the short run and the long run. It was also revealed that interest rates had multiple structural breaks in the years 2002, 2009 and 2014, respectively. The study recommended that the monetary authorities should utilize the monetary policy, the interest rate, in particular, to promote private domestic investment by keeping interest rates low. In so doing, private domestic investment will improve leading to increased employment, productivity, and growth of the economy.
CAGI6 ID-Challenge: Assessment of phenotype and variant predictions in 415 children with Neurodevelopmental Disorders (NDDs)
Authors: Aspromonte Maria Cristina , Conte Alessio Del , Zhu Shaowen , Tan Wuwei , Shen Yang , Zhang Yexian , Li Qi , Wang Maggie Haitian , Babbi Giulia , Bovo Samuele , Martelli Pier Luigi , Casadio Rita , Althagafi Azza , Toonsi Sumyyah , Kulmanov Maxat , Hoehndorf Robert , Katsonis Panagiotis , Williams Amanda , Lichtarge Olivier , Xian Su , Surento Wesley , Pejaver Vikas , Mooney Sean D. , Sunderam Uma , Sriniva Rajgopal , Murgia Alessandra , Piovesan Damiano , Tosatto Silvio C. E. , Leonardi Emanuela 
Published: August 2023

Abstract

In the context of the Critical Assessment of the Genome Interpretation, 6th edition (CAGI6), the Genetics of Neurodevelopmental Disorders Lab in Padua proposed a new ID-challenge to give the opportunity of developing computational methods for predicting patient’s phenotype and the causal variants. Eight research teams and 30 models had access to the phenotype details and real genetic data, based on the sequences of 74 genes (VCF format) in 415 pediatric patients affected by Neurodevelopmental Disorders (NDDs). NDDs are clinically and genetically heterogeneous conditions, with onset in infant age. In this study we evaluate the ability and accuracy of computational methods to predict comorbid phenotypes based on clinical features described in each patient and causal variants. Finally, we asked to develop a method to find new possible genetic causes for patients without a genetic diagnosis. As already done for the CAGI5, seven clinical features (ID, ASD, ataxia, epilepsy, microcephaly, macrocephaly, hypotonia), and variants (causative, putative pathogenic and contributing factors) were provided. Considering the overall clinical manifestation of our cohort, we give out the variant data and phenotypic traits of the 150 patients from CAGI5 ID-Challenge as training and validation for the prediction methods development.
Lentivirus-mediated knockdown of Ski inhibits glial scar formation and promotes axonal regeneration and functional recovery after spinal cord injury in rats
Authors: Wang Zhiqiang , Ran Rui , Ma Chun-Wei , Lv Jia-Yang , Zhou Sheng , Zhang Hai-Hong 
Published: August 2023

Abstract

The glial scar that forms at the site of injury after spinal cord injury (SCI) is an important physical and biochemical barrier that prevents axonal regeneration and thus delays functional recovery. Ski is a multifunctional transcriptional co-regulator that is involved in a wide range of physiological and pathological processes in humans. Previous studies by our group found that Ski is significantly upregulated in the spinal cord after in vivo injury and in astrocytes after in vitro activation, suggesting that Ski may be a novel molecule regulating astrocyte activation after spinal cord injury. Further studies revealed that knockdown or overexpression intervention of Ski expression could significantly affect the proliferation and migration of activated astrocytes. To further verify the effect of knockdown of Ski expression in vivo on glial scar formation and functional recovery after spinal cord injury, we prepared a rat spinal cord injury model using Allen's percussion method and used lentivirus as a vector to mediate the downregulation of Ski in the injured spinal cord. The results showed that knockdown of Ski expression after spinal cord injury significantly inhibited the expression of Glial Fibrillary Acidic Protein (Gfap) and Vimentin, the hallmark molecules of glial scar, and increased the expression of Neurofilament-200 (Nf-200), a key molecule for axonal regeneration, and Synaptophysin, a key molecule for synapse formation. In addition, knockdown of Ski after spinal cord injury also promoted the recovery of motor function. Taken together, these results demonstrate that Ski is an important regulator of glial scar formation at the injury site and promotes axonal regeneration and synapse formation after spinal cord injury, and is a potential target for targeted therapy after spinal cord injury.