bluuebunny/crossref_metadata_2025_split huggingface dataset:
Zoning of the reaction of the tissues of the implantation area after prosthetic repair in abdominal hernias in experiment
Authors: Lukoyanychev E. E. , Izmailov S. G. , Evsyukov D. A. , Nikolskij V. O. , Mironov A. A. , Panyushkin A. V. 
Published: December 2022

Purpose of the study. Development of criteria for evaluating the reaction of tissues in the implantation area after prosthetic repair of the hernia ring in an experiment using new digital image processing technologies.Materials and methods. The experiment was carried out on 13 Wistar rats of different sexes. Under anesthesia, a 4 × 2 cm mesh prosthesis was implanted in the layer similar to the onlay epiaponeurotic. The preparation and staining of each preparation was carried out in two versions: with hematoxylin-eosin and according to Mallory on different glasses. The seasons for performing experiments are winter, summer. Microphotography was performed on a medical transmitted light microvisor Microvisor μVizo‑103 (AD LOMO, Russia) with a 3.2 Mpx matrix (full frame size 1024 × 882 px, infoband width 88 px) with Planachromat and Stigachromat lenses with a digital scale × 1 (i.e. no digital zoom). Microphoto processing was performed using the ImageJ 1.53k program (version for public use). The criterion for including a microphoto in the calculation of indicators was the presence of an ingrown implant fiber in the preparation or a cavity surrounding the implant.Results. The zone adjacent to the implant, with a width of about 50 µm ("the zone of changes in adjacent tissues") significantly differs from the "zone of changes in distant tissues" by a more pronounced inflammatory reaction due to a larger absolute number of lymphocytes (р = 0.019 and fibroblasts (р = 0.017), giant cells of foreign bodies (р < 0.001), larger vascular area (р < 0.001) and extravasations (р = 0.002). The study of the "zone of changes in adjacent tissues" is of key importance in assessing the local response of the body to implantation. The key zones of the implantation area are identified: "the cavity surrounding the implant", "the zone of changes in adjacent tissues", "the zone of changes in distant tissues". The calculation of indicators within these zones allows you to get more detailed results when comparing study groups in the experiment.Conclusion. An effective method for assessing the reaction of tissues in the implantation area after prosthetic hernia repair in an experiment using new digital imaging technologies that can be used using a conventional optical microscope and standard staining methods is proposed.
Prognostic significance of the logistic regression model for assessing the risk of recurrence in patients with prostate cancer after radical prostatectomy
Authors: Reva S. A. , Arnautov A. V. , Klitsenko O. A. , Petrov S. B. 
Published: December 2022

Purpose of the study. The study’s objective is to investigate the influence of risk factors for recurrence of prostate cancer (PCa) after radical surgical treatment on the unfavourable course of recurrence of the disease with the formation of a set of the most significant factors of a model that reflects the likelihood of relapse.Materials and methods. A retrospective analysis of clinical, pathomorphological and perioperative parameters of 803 patients with PCa after radical prostatectomy was carried out. By means of logistic regression, a model for assessing the risk of recurrence for patients with prostate cancer was built, which included 7 indicators, one of which was measured by quantity (time between biopsy and start of treatment) and six categorical ones (ISUP grade group, cT, cN+, positive surgical margin, PSA level after surgery, pN+). The construction of a logistic regression model consisted in obtaining a characteristic of the logistic function Ψ for the standard equation y = exp(ψ) / (1 + exp(ψ)).Results. Substituting the coefficients obtained for each of the indicators, we obtain Ψ to assess the risk of relapse Ψ = 0.485 × X1+ 1.937 × X2 + 0.789 × X3 + 3.229 × X4 + 0.443 × X5 + 0.880 × X6 + 0.015 × X7–6.65. In the resulting formula, each of the regression coefficients describes the size of the contribution of the corresponding factor. In our case, all regression coefficients were positive, which means that this factor increases the overall risk of relapse. The quality of the resulting model is determined by the chi-square = 284.3; p < 0.001; OR = 28.45. The sensitivity of this model was 86.6 %, specificity 81.5 %, diagnostic accuracy 82.7 %.Conclusion. This model makes it possible to obtain the probability of recurrence after radical prostatectomy depending on the severity of a specific set of predictive signs (a positive effect is predicted for y > 0.5, a negative one for y ≤ 0.5) and the degree of influence of one or a group of predictive signs on the likelihood of relapse, such as the ISUP grade group, locally advanced disease, clinically detectable lymph node lesion, positive surgical margin, PSA level of more than 0.09 ng/ml 1 month after surgery, the presence of regional metastases and the time between biopsy and the start of treatment.
Combined-order Algorithm using Promethee Method Approach and Analytic Hierarchy Decision for Chunk Allocation in LTE Uplink Systems
Authors: Fahmi Arfianto , Asvial Muhamad , Gunawan Dadang 
Published: December 2022

The problem of chunk-based resource allocation for the uplink of Long Term Evolution is investigated. In this paper, a combined order using the promethee method and analytic hierarchy decision for chunk allocation algorithm is proposed. The utility of each order is sorted based on promethee method approach so that the utility of each order could be approximated as the average of all criteria on each order. To decide the best allocation, analytic hierarchy process score is assigned to its order based on their decision criteria weighting factor to find the best allocation. Using a particular weighting factor, the proposed algorithms outperform the previous mean greedy algorithms which use user-order allocation in term of spectral efficiency and data rate fairness without increase the time complexity. It also outperform iterative swapping chunk algorithm in term of data rate fairness.
A Survey on Dynamic Spectrum Access Techniques in Cognitive Radio Networks
Authors: Benmammar Badr , Amraoui Asma , Krief Francine 
Published: December 2022

The idea of Cognitive Radio (CR) is to share the spectrum between a user called primary, and a user called secondary. Dynamic Spectrum Access (DSA) is a new spectrum sharing paradigm in cognitive radio that allows secondary users to access the abundant spectrum holes in the licensed spectrum bands. DSA is an auspicious technology to alleviate the spectrum scarcity problem and increase spectrum utilization. While DSA has attracted many research efforts recently, in this paper, a survey of spectrum access techniques using cooperation and competition to solve the problem of spectrum allocation in cognitive radio networks is presented.
The progressiveness of Quranic interpretation in the fatwa of Muhammadiyah on female circumcision
Authors: Mundzir Ilham , Muthmainnah Yulianti 
Published: December 2022

The Indonesian Muslim community has been accustomed to requesting and carrying out religious Fatwas related to ibadah (worship) or mu’amalah (worldly dealings) in religious organizations that gave rise to various Fatwas, such as Muhammadiyah, Nahdlatul Ulama (NU), and the Indonesian Ulama Council (MUI). This paper focuses on female circumcision, by comparing how the same Quranic verses and Hadith can have various interpretations and Fatwas. Although the source of producing the Fatwa is the same (al-Quran and Hadith), the Fatwa that emerges from three Islamic organization are completely different. Qualitative research methods include interviews and literature review, with Fatwas from religious organizations and interviews being the primary sources. This research concludes that Fatwa from Muhammadiyah is considered the most progressive and has a strong perspective on gender equality and justice by prohibiting female circumcision. On the other hand, the Fatwa from NU and MUI supports and allows female circumcision, even though it has negative impacts on women and baby girls, including the death of baby girls.
Favoriser l’alignement pédagogique lors d’une migration en formation à distance: Une Démarche SoTL
Authors: Gouin Marie-Michelle , Denis Constance , Lefebvre Nathalie , Lanctôt Stéphanie , Belisle Marilou 
Published: December 2022

Avant la pandémie de COVID-19, l’équipe programme d’un certificat universitaire de premier cycle en santé en sécurité du travail a entamé une migration en formation à distance touchant l’ensemble des cours. L’approche visait entre autres, à répondre à la diversité et aux besoins des cohortes estudiantines en formation continue. Les activités d’intégration, particulièrement l’activité pédagogique INT110, posaient certains défis : divers enjeux (ex. absentéisme, démotivation, désengagement et faible taux de réussite) étaient rapportés par la professeure responsable. Une démarche de Scholarship of Teaching and Learning (SoTL) a été menée pour réfléchir et documenter ces enjeux, améliorer les pratiques pédagogiques et l’apprentissage des personnes étudiantes. La démarche SoTL comporte six phases itératives: l’analyse, l’appropriation, la conception, l’implantation, l’évaluation et la diffusion. La phase d’analyse a mis en lumière des enjeux liés à l’alignement pédagogique. L’approche expérientielle et l’apprentissage par projet ont été retenus. L’activité pédagogique a été entièrement revue dans la phase de conception pour en maximiser l’alignement pédagogique en s’appuyant sur des cadres théoriques reconnus qui ont été explorés lors de la phase d’appropriation. L’activité pédagogique a été recentrée autour de la planification d’une intervention en entreprise. L’implantation du nouveau projet d’apprentissage s’est faite en deux temps (2020 et 2021). La phase d’évaluation a été reportée au printemps 2022. L’analyse préliminaire des résultats obtenus laisse présager des retombées positives de l'innovation pédagogique mise en œuvre.
Truth and Reconciliation Through Inquiry-based Collaborative Learning
Authors: Houghton Deirdre , Soles Gary , Vogelsang Andrew , Irvine Valerie , Prince Francois , Prince Leona , Martin Carla , Restoule Jean-Paul , Paskevicius Michael 
Published: December 2022

This paper overviews a project conducted at Fort St. James Secondary School in the Nechako Lakes School District, which is in Northern British Columbia, Canada. Three highschool teachers from different disciplines (Social Studies, Digital Media, and Carpentry) launched a cross-curricular inquiry-based project in partnership with local knowledge holders and School District 91, focusing on truth and reconciliation, that connected the learners in their highschool and the broader community, including knowledge holders from the local Indigenous communities. Those engaged in the project examined questions around what truth and reconciliation meant to the learners and its significance. Resulting products included a legacy wall containing individual learning represented in motifs, design of the feather using wood from around the world, and a video documentary containing interviews from school and community stakeholders. We share information on how to access the video documentary.
Comparison of Nitroaromatic Compounds Metabolites Types by Sequencing Performance of Anaerobic-Aerobic and Aerobic-Anaerobic Processes
Authors: Teimouri Fahimeh , Amin Mohammad Mehdi , Sadani Mohsen , Bina Bijan , Khanahmad Hossein 
Published: December 2022

Introduction: Xenobiotic contamination is a global concern. Nitroaromatic compounds enter the environment through ammunition, ordnance disposal, burning the outdoors, and leakage of ammunition. Thirty percent of explosives enter the environment without any change, which can cause pollution of soil, water, and health concerns. So, effective remediation of the contaminated area is necessary.
Materials and Methods: Soil bioreactors consisted of plastic pans placed in larger pans. Explosives were analyzed using a High-Performance Liquid Chromatography (HPLC) system, Model 486 UV detector, and a Nova Pak C18 guard column. LC-MS detected intermediates on an RP18 analytical column equipped with a C18 guard column.
Results: Rhamnolipid significantly affected 2,4,6-trinitrotoluene (TNT) and Pentaerythritol tetranitrate (PETN) biodegradation rates with the help of indigenous bioaugmentation. The mentioned condition was also effective on the maximum bacterial growth in various nitroaromatics (S0) concentrations, in which the top change occurred. The specific growth rate was foremost in a setup containing microbial inoculated and biosurfactant (0.19) responding to 800 mg/kg TNT and 150 mg/kg PETN. The maximum bacterial enumeration of sludge and biosurfactant were 4.8 × 108 and 4.1 × 108 CFU/g, respectively. The aerobic-anaerobic sequence could be able to produce less harmful metabolites. In an aerobic-anaerobic sequence process, using the anaerobic process could help complete the azo compounds degradation in the aerobic stage.
Conclusion: Aerobic-anaerobic condition is suitable for bioremediation contaminated explosive sites and achieving complete mineralization. Generally, this proposed method is possible for in situ bioremediation.
Modelling Liquified Petroleum Gas Prices in Nigeria Using Machine Learning Models
Authors: Ogundunmade Tayo P. , Adepoju Adedayo A. 
Published: December 2022

The usage of Liquefied Petroleum Gas in households has been to increase in recent years. The energy used by households has proved difficult to forecast due to the nature of the independent variables. In recent years, deep learning models has been broadly utilized in the machine learning area to model time series data. Most noticeable is in the field of forecasting. In this work, Neural Network Autoregressive model (NNETAR), Naive forecasting and the Autoregressive Integrated Moving Average (ARIMA) models were used to model the price of Liquefied Petroleum Gas prices(LPG) of 37 states (including the FCT) in Nigeria, with input variables in the form of the price of refilling LPG for 12.5 kg from January 2016 to April 2019 covering a 1480 data points. The Mean Absolute Percentage Errors was used to measure the performance of the model. The result shows that Naive produced lower MAPE for more states compare to NNETAR and ARIMA models.
Geoelectric Section of the Coastal Region of the Chukchi Sea near the Cape Schmidt Observatory
Authors: Starzhinskii S.S. , Yoshikawa A. , Khomutov S.Yu. 
Published: December 2022

Abstract
—This paper presents the results of 3D inversion of magnetovariational tippers obtained at the Cape Schmidt observatory via digital processing of geomagnetic variation records performed by the MAGDAS-I magnetometer. 3D tipper frequency inversion is carried out using the ModEM software. The result is horizontal and vertical sections in the coastal strip of the Chukchi Sea in a spatial region with a dimension of 300 × 300 × 200 km along the X, Y, and Z axes, respectively. The geoelectric section of the investigated region contains both surface and deep conductive blocks located at different azimuths relative to a measurement point. The surface conductive anomaly near the observatory with a resistivity of ≈3 Ohm·m is located in the southeast direction at depths of a few hundred meters. The other conducting inhomogeneity is larger and located in the same direction, but at a distance of about 25–30 km and depths of 4–16 km. The resistivity of its central region at a depth of 8 km is equal to 1 Ohm·m. From the side of the South Chukchi Depression, there is an inclined conductive block in the Chukchi Sea, located closer to the coast to the bottom of the Earth’s crust, and the maximum resistivity of this block in the central part at a depth of 20 km is equal to ≈7 Ohm·m. The most noticeable feature of the section is a massive upper-mantle conductive block under the continent at depths of 50–120 km with a resistivity of 3–4 Ohm·m in the central part at depths of 70–85 km. Deeper into the continent, the block is slightly inclined to the southeast. There are visible conductive regions that connect this block with upstream conductive formations. The epicenters of weak crustal earthquakes recorded in the region are located above the northwestern marginal part of the upper-mantle block, including its central region. Possible mechanisms of high electrical conductivity of anomalous blocks are discussed.
Identificação de potenciais inibidores da enzima NS2B-NS3 do Zika Vírus
Authors: Clemente Dias Renieidy Flávia 
Published: December 2022

O vírus Zika (ZIKV) são flavivírus pertencentes à família flaviviridae, que são transmitidos pela picada do vetor infectado; nesse caso, mosquito do gênero Aedes aegypti. A replicação viral é função da proteína não estrutural NS3-pro que atua em associação com NS2B, aumentando a eficiência enzimática. Assim, esse domínio da protease N2B-NS3 apresenta um alvo atrativo para o planejamento de novos fármacos antivirais. Diante disto, este artigo buscou abordar a importância farmacológica dos heterocíclicos benzotiazóis e trouxe exemplos de derivados benzotiazóis como novos candidatos a fármacos capazes de inibirem a protease N2B-NS3 do ZIKV.
Palavras-chave: NS2B-NS3; ZIKV; Aedes aegypti.
Abstract
Identification of potential inhibitors of the Zika Virus NS2B-NS3 enzyme
The Zika virus (ZIKV) are flaviviruses belonging to the flaviviridae family, which are transmitted by the bite of an infected vector, in this case, a mosquito of the genus Aedes aegypti. Viral replication is a function of the non-structural protein NS3-pro that works in association with NS2B, increasing enzymatic efficiency. Thus, this domain of the N2B-NS3 protease presents an attractive target for the design of new antiviral drugs. Therefore, this article sought to address the pharmacological importance of heterocyclic benzothiazoles and brought examples of benzothiazole derivatives as new drug candidates capable of inhibiting the N2B-NS3 protease of ZIKV.
Keywords: NS2B-NS3; ZIKV; Aedes aegypti.
Resumen
Identificación de posibles inhibidores de la enzima NS2B-NS3 del virus del Zika
El virus Zika (ZIKV) son flavivirus pertenecientes a la familia flaviviridae, que se transmiten por la picadura de un vector infectado, en este caso, un mosquito del género Aedes aegypti. La replicación viral es una función de la proteína no estructural NS3-pro que trabaja en asociación con NS2B, ampliando la eficiencia enzimática. Por ello, este dominio de la proteasa N2B-NS3 presenta un objetivo atractivo para el diseño de nuevos fármacos antivirales. Frente a esto, el artículo buscó abordar la importancia farmacológica de los benzotiazoles heterocíclicos y trajo ejemplos de derivados de benzotiazol como nuevos candidatos a fármacos capaces de inhibir la proteasa N2B-NS3 del ZIKV.
Palavras clave: NS2B-NS3; ZIKV; Aedes aegypti.
Ingresos, tecnología y capacitación de productores rurales de trucha (Oncorhynchus mykiss), estudio de caso en el lago Titicaca
Authors: Apaza Quispe Ismena , Blanco Espezúa María del Pilar 
Published: December 2022

La truchicultura se introdujo en la región de Puno desde la década de los 70’ sin embargo los productores de trucha en la actualidad afrontan diversos problemas, como el manejo empírico, escasa tecnología en la crianza y gestión empírica de la producción y comercialización de trucha. En esta investigación se identifican y analizan los factores socioeconómicos que ejercen efectos en la mejora de ingresos en las familias productoras de trucha de la Asociación “Brisas del Titicaca” de Chucuito en Puno, Perú. Desde una perspectiva económica y social, a partir del método inductivo, a partir de una población de 30 acuicultores, con áreas de concesión para la producción entre 1 y 1,5 ha. Las unidades productivas alcanzan ingresos mensuales de 21.000 PEN (aprox. 6234 USD; T.C 2018) Al aplicar un modelo econométrico probit ordenado, considerando como variables dependientes seis niveles de ingreso (Y) y como variables independientes: edad (E), nivel educativo alcanzado (NE), número de capacitaciones en crianza de truchas (NC), área de concesión (AC), tipo de instalación acuícola-tecnológica (TI) y acceso a crédito financiero (AF). Se encontró que el nivel educativo (NE), el número de capacitaciones (NC), el tipo de instalación en las jaulas de crianza de truchas (TI) y el acceso al crédito financiero (AF) fueron las variables significativas, para lograr mayor probabilidad para generar mayores niveles de ingresos en su actividad productiva. Así mismo se encontró que es necesario fortalecer la capacitación y mejora tecnológica, así como el acceso al crédito en la producción rural de truchas.
Soil Porosity Conditions in Flood-Prone Areas of the Prosperous Swamp of Bengkulu City Based on Geoelectrical Measurement
Authors: M. Tio Fajri , Yunita Astra , Bernaldi Rafli , Sugianto Nanang 
Published: December 2022

Surface porosity conditions in part of flood-prone areas at Rawa Makmur Village have been mapped from the surface to a depth of 30 meters. The aims of this research are to identify the infiltration of soil which is described by variations in resistivity and rock porosity values. It is obtained from the 1D geoelectric method using Vertical Electrical Sounding and as many as 10 measurement points. According to analysis, it is explained that Rawa Makmur area has low porosity and resistivity values. The porosity conditions in the observation point area were in very bad conditions. The infiltration process is very slow, causing the accumulation of a large amount of water mass and a fairly high pool of water. It also showed that the water flowing in this area was difficult to infiltrate, so it caused the Rawa Makmur area to become flooded when it rained.
Analysis of Skin Radiation Injury After External Curative and Palliative Radiotherapy of Cervix Cancer with Linac
Authors: Suryani Sri , Mirfauddin  , Abdullah Bualkar , Rahmat Roni 
Published: December 2022

Radiotherapy is a powerful tool for tumour control and treatment for various types of cancer. Despite the technological advances, cancer patients are still experiencing skin radiation injury. This study analyzed the probability of the skin radiation injury experienced by cervical cancer patients after external curative and palliative radiotherapy. This research was conducted at the Hasanuddin University Teaching Hospital in the Radiology section. The instrument used LINAC 6 MV external radiotherapy with the Varian brand. The state of the cancer of the samples was stage 2 B, and 3 B. The application of the dose rate for the two stages in curative therapy did not differ, such as 6.06 Gy/min to 8.26 Gy/min. On the contrary, palliative therapy uses a dose rate of 11.06 Gy/min to 13.47 Gy/min. This dose rate is higher than the curative dose rate because this therapy aims to reduce the size of cancer.