bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nonlinear Inflatable Actuators for Distributed Control in Soft Robots
Authors: Van Raemdonck Bert , Milana Edoardo , De Volder Michael , Reynaerts Dominiek , Gorissen Benjamin 
Published: May 2023

AbstractAs soft robotic systems grow in complexity and functionality, the size and stiffness of the needed control hardware severely limits their application potential. Alternatively, functionality can be embodied within actuator characteristics, drastically reducing the amount of peripherals. Functions such as memory, computation, and energy storage then result from the intrinsic mechanical behavior of precisely designed structures. Here, actuators are introduced with tunable characteristics to generate complex actuation sequences from a single input. Intricate sequences are made possible by harnessing hysteron characteristics encoded in the buckling of a cone‐shaped shell incorporated in the actuator design. A large variety of such characteristics are generated by varying the actuator geometry. This dependency is mapped and used for creating a tool to determine the actuator geometry that yields a desired characteristic. Using this tool, a system with six actuators is created that plays the final movement of Beethoven's Ninth Symphony with a single pressure supply.
All‐Optical Multiplexed Meta‐Differentiator for Tri‐Mode Surface Morphology Observation
Authors: Liang Xiao , Zhou Zhou , Li Zile , Li Jiaxin , Peng Chang , Cui Hao , Wei Kai , He Zhixue , Yu Shaohua , Zheng Guoxing 
Published: May 2023

AbstractCurrent optical differentiators are generally limited to realizing a single differential function once fabricated. Herein, a minimalist strategy in designing multiplexed differentiators (1st‐ and 2nd‐order differentiations), implemented with a Malus metasurface consisting of single‐sized nanostructures is proposed, thus improving the functionality of optical computing devices without the cost of complex design and nanofabrication. It is found that the proposed meta‐differentiator exhibits excellent differential‐computation performance and can be used for simultaneous outline detection and edge positioning of objects, corresponding to the functions of the 1st‐ and 2nd‐order differentiations respectively. Experiments with biological specimens showcase that boundaries of biological tissues can not only be identified, but also the edge information for realizing high‐precision edge positioning is highlighted. The study provides a paradigm in designing all‐optical multiplexed computing meta‐devices, and initiates tri‐mode surface morphology observation by combining meta‐differentiator with optical microscopes, which can find their applications in advanced biological imaging, large‐scale defect detection, and high‐speed pattern recognition, etc.
Ultrasensitive Molecular Fingerprint Retrieval Using Strongly Detuned Overcoupled Plasmonic Nanoantennas
Authors: Li Dongxiao , Zhou Hong , Chen Ziwei , Ren Zhihao , Xu Cheng , He Xianming , Liu Tao , Chen Xin , Huang He , Lee Chengkuo , Mu Xiaojing 
Published: May 2023

AbstractTailoring light‐matter interactions via plasmonic nanoantennas (PNAs) has emerged as a breakthrough technology for spectroscopic applications. The detuning between molecular vibrations and plasmonic resonances, as a fundamental and inevitable optical phenomenon in light‐matter interactions, reduces the interaction efficiency, resulting in a weak molecule sensing signal at the strong detuning state. Here, it is demonstrated that the low interaction efficiency from detuning can be tackled by overcoupled PNAs (OC‐PNAs) with a high ratio of the radiative to intrinsic loss rates, which can be used for ultrasensitive spectroscopy at strong plasmonic‐molecular detuning. In OC‐PNAs, the ultrasensitive molecule signals are achieved within a wavelength detuning range of 248 cm−1, which is 173 cm−1 wider than previous works. Meanwhile, the OC‐PNAs are immune to the distortion of molecular signals and maintain a lineshape consistent with the molecular signature fingerprint. This strategy allows a single device to enhance and capture the full and complex fingerprint vibrations in the mid‐infrared range. In the proof‐of‐concept demonstration, 13 kinds of molecules with some vibration fingerprints strongly detuning by the OC‐PNAs are identified with 100% accuracy with the assistance of machine‐learning algorithms. This work gains new insights into detuning‐state nanophotonics for potential applications including spectroscopy and sensors.
As‐Grown Miniaturized True Zero‐Order Waveplates Based on Low‐Dimensional Ferrocene Crystals
Authors: Li Zhipeng , Ma Xuezhi , Wei Fengxia , Wang Dapeng , Deng Zeyu , Jiang Mengting , Siddiquee Arif , Qi Kun , Zhu Di , Zhao Meng , Shen Mengzhe , Canepa Pieremanuele , Kou Shanshan , Lin Jiao , Wang Qian 
Published: May 2023

AbstractAs basic optical elements, waveplates with anisotropic electromagnetic responses are imperative for manipulating light polarization. Conventional waveplates are manufactured from bulk crystals (e.g., quartz and calcite) through a series of precision cutting and grinding steps, which typically result in large size, low yield, and high cost. In this study, a bottom‐up method is used to grow ferrocene crystals with large anisotropy to demonstrate self‐assembled ultrathin true zero‐order waveplates without additional machining processing, which is particularly suited for nanophotonic integration. The van der Waals ferrocene crystals exhibit high birefringence (Δn (experiment) = 0.149  ±  0.002 at 636 nm), low dichroism Δκ (experiment) = −0.0007 at 636 nm), and a potentially broad operating range (550 nm to 20 µm) as suggested by Density Functional Theory (DFT) calculations. In addition, the grown waveplate's highest and the lowest principal axes (n1 and n3, respectively) are in the a–c plane, where the fast axis is along one natural edge of the ferrocene crystal, rendering them readily usable. The as‐grown, wavelength‐scale‐thick waveplate allows the development of further miniaturized systems via tandem integration.
Dual‐Wavelength Comparative Imaging Based on a Novel NIR‐II/IIb Emissive Rare Earth‐Doped Nanoparticle
Authors: Liu Ruiqi , Qiu Yihua , Wu Fengxia , Duan Shuang , Suo Yongkuan , Chang Baisong , Ren Ying , Tian Mei , Liu Hongguang , Cheng Zhen 
Published: May 2023

AbstractThe second near‐infrared biological window two (NIR‐II, 1000–1700 nm) imaging has made remarkable achievements in fluorescence imaging of diseases. Here, this work takes advantage of the rich spectral properties of rare‐earth doped nanoparticles (RENPs) and their capability to present multiple emission peaks in different luminescence regions simultaneously; novel RENPs are synthesized that have emission peaks in the NIR‐II1000nm (1000–1300 nm) region and enhanced emission in the NIR‐IIb (1500–1700 nm) window and are named as NEU‐RENPs. These RENPs with new compositions enable a fair comparison to evaluate their imaging performance in NIR‐II1000nm and NIR‐IIb regions under the same conditions. The imaging abilities of the resulted nanoparticles in NIR‐II1000 nm and NIR‐IIb regions are investigated systematically for local blood vessels, tumor vessels, acute inflammatory vessels, arterial thrombosis, cerebrovascular inflammation, and brain injury models. The results indicate that imaging of NIR‐IIb shows higher resolution and sensitivity than that of NIR‐II1000nm, and it has a stronger ability to accurately distinguish normal and pathological tissues. Interestingly, the fuzzy image of NIR‐II1000nm reveals more information about the background structure of the target, which is difficult to be achieved in NIR‐IIb imaging. The results prove NEU‐RENPs based NIR‐IIb imaging is preferable for biomedical applications.
Machine Learning and Pan‐Cancer Analysis of Tertiary Lymphoid Structures: A Potential Target for Survival and Drug Treatment
Authors: Lai Jianguo , Cao Yuchen , Zhang Jiexin , Wang Jinglong , Du Yawen , He Yan , Luo Yuting , Liao Ning 
Published: May 2023

AbstractTertiary lymphoid structure (TLS) is considered to be closely related to tumor prognosis and immune response. Therefore, it has predictable clinical significance for survival prognosis and cancer drug treatment to build TLS signature of pan‐cancer. The transcriptome sequencing data of The Cancer Genome Atlas pan‐cancer analysis are obtained from UCSC Xena, including 33 cancer types (N = 10 066). A 15 TLS genes‐based TLSscore is constructed using the Random Forest and Cox regression analyses. Then, according to TLS signature, patients are classified into low‐ and high‐risk groups. Then, the differences between the two groups in terms of survival prognosis, functional enrichment, immune infiltration, and drug sensitivity are further explored. On the basis of machine learning algorithm, TLS signature has satisfactory prediction performance for the prognosis of pan‐cancer patients. A nomogram with high predictive performance is formulated by incorporating TLS signature and clinical features. The function enrichment analysis suggests that TLS signature may be related to the key pathways of immunotherapy for pan‐cancer, and shows significant differences among groups at the immune checkpoint genes. In general, a novel TLSscore‐based model is established through comprehensive analysis of TLS genes, which can accurately predict the clinical prognosis and drug sensitivity of pan‐cancer.
Microneedle Patches with Antimicrobial and Immunomodulating Properties for Infected Wound Healing
Authors: Li Shengbo , Wang Xuemei , Yan Zhiyao , Wang Tian , Chen Zhenbing , Song Heng , Zheng Yongbin 
Published: May 2023

AbstractTreatment of infected wounds remains a challenge owing to antibiotic resistance; thus, developing smart biomaterials for the healing of infected wounds is urgently needed. In this study, a microneedle (MN) patch system with antimicrobial and immunomodulatory properties is developed to promote and accelerate infected wound healing. In the MN patch (termed PFG/M MNs), a nanoparticle with polydopamine (PDA)‐loaded iron oxide is grafted with glucose oxidase (GOx) and hyaluronic acid (HA) and then integrated into the tips, and amine‐modified mesoporous silica nanoparticles (AP‐MSNs) are incorporated into the bases. Results show that PFG/M MNs eradicate bacterial infections and modulate the immune microenvironment, combining the advantages of chemodynamic therapy, photothermal therapy, and M2 macrophage polarization from Fe/PDA@GOx@HA in the tips as well as anti‐inflammatory effect of AP‐MSNs from the MN bases. Thus, the PFG/M MN system is a promising clinical candidate for promoting infected wound healing.
Latin American Initiative for Lifestyle Intervention to Prevent Cognitive Decline (LatAm‐FINGERS): Study design and harmonization
Authors: Crivelli Lucia , Calandri Ismael Luis , Suemoto Claudia Kimie , Salinas Rosa María , Velilla Lina Marcela , Yassuda Mônica Sanches , Caramelli Paulo , Lopera Francisco , Nitrini Ricardo , Sevlever Gustavo Emilio , Sosa Ana Luisa , Acosta Daisy , Baietti Ana María Charamelo , Cusicanqui María Isabel , Custodio Nilton , De Simone Sergio Dansilio , Derio Carolina Delgado , Duque‐Peñailillo Lissette , Duran Juan Carlos , Jiménez‐Velázquez Ivonne Z. , Leon‐Salas Jorge Mario , Bergamo Yanina , Clarens María Florencia , Damian Andrés , Demey Ignacio , Helou María Belén , Márquez Carlos , Martin María Eugenia , Martin Maria da Graça Morais , Querze Diego , Surace Ezequiel Ignacio , Acosta‐Egea Sabrina , Aguirre–Salvador Esteban , de Souza Leonardo Cruz , Cançado Gustavo Henrique da Cunha Peixoto , Brucki Sonia Maria Dozzi , Friedlaender Clarisse Vasconcelos , Gomes Karina Braga , Gutierrez Myriam , Ríos Carlos Laforcada , Galindo Joyce Graciela Martinez , Montesinos Rosa , Nuñez‐Herrera Alberto , Ospina‐Henao Sebastián , Rodríguez Guillermina , Masson Victoria Ruiz , Sánchez Mónica , Schenk Christian E. , Soto Ligia , Barbosa Maira Tonidandel , Tosatti Jéssica Abdo Gonçalves , Vicuña Yosselin , Espeland Mark , Hakansson Krister , Kivipelto Miia , Baker Laura , Snyder Heather , Carrillo María , Allegri Ricardo Francisco 
Published: May 2023

AbstractINTRODUCTIONLatin American Initiative for Lifestyle Intervention to Prevent Cognitive Decline (LatAm‐FINGERS) is the first non‐pharmacological multicenter randomized clinical trial (RCT) to prevent cognitive impairment in Latin America (LA). Our aim is to present the study design and discuss the strategies used for multicultural harmonization.METHODSThis 1‐year RCT (working on a 1‐year extension) investigates the feasibility of a multi‐domain lifestyle intervention in LA and the efficacy of the intervention, primarily on cognitive function. An external harmonization process was carried out to follow the FINGER model, and an internal harmonization was performed to ensure this study was feasible and comparable across the 12 participating LA countries.RESULTSCurrently, 1549 participants have been screened, and 815 randomized. Participants are ethnically diverse (56% are Nestizo) and have high cardiovascular risk (39% have metabolic syndrome).DISCUSSIONLatAm‐FINGERS overcame a significant challenge to combine the region's diversity into a multi‐domain risk reduction intervention feasible across LA while preserving the original FINGER design.
Alzheimer's disease brain‐derived extracellular vesicles reveal altered synapse‐related proteome and induce cognitive impairment in mice
Authors: Bodart‐Santos Victor , Pinheiro Lisandra S. , da Silva‐Junior Almir J. , Froza Rudimar L. , Ahrens Rosemary , Gonçalves Rafaella A. , Andrade Mayara M. , Chen Yan , Alcantara Carolina de Lima , Grinberg Lea T. , Leite Renata E. P. , Ferreira Sergio T. , Fraser Paul E. , De Felice Fernanda G. 
Published: May 2023

AbstractINTRODUCTIONExtracellular vesicles (EVs) have been implicated in the spread of neuropathology in Alzheimer's disease (AD), but their involvement in behavioral outcomes linked to AD remains to be determined.METHODSEVs isolated from post mortem brain tissue from control, AD, or frontotemporal dementia (FTD) donors, as well as from APP/PS1 mice, were injected into the hippocampi of wild‐type (WT) or a humanized Tau mouse model (hTau/mTauKO). Memory tests were carried out. Differentially expressed proteins in EVs were assessed by proteomics.RESULTSBoth AD‐EVs and APP/PS1‐EVs trigger memory impairment in WT mice. We further demonstrate that AD‐EVs and FTD‐EVs carry Tau protein, present altered protein composition associated with synapse regulation and transmission, and trigger memory impairment in hTau/mTauKO mice.DISCUSSIONResults demonstrate that AD‐EVs and FTD‐EVs have negative impacts on memory in mice and suggest that, in addition to spreading pathology, EVs may contribute to memory impairment in AD and FTD.Highlights
Aβ was detected in EVs from post mortem AD brain tissue and APP/PS1 mice.
Tau was enriched in EVs from post mortem AD, PSP and FTD brain tissue.
AD‐derived EVs and APP/PS1‐EVs induce cognitive impairment in wild‐type (WT) mice.
AD‐ and FTD‐derived EVs induce cognitive impairment in humanized Tau mice.
Proteomics findings associate EVs with synapse dysregulation in tauopathies.
Redox‐Bipolar Polyimide Two‐Dimensional Covalent Organic Framework Cathodes for Durable Aluminium Batteries
Authors: Liu Yannan , Lu Yiyue , Hossain Khan Arafat , Wang Gang , Wang Yong , Morag Ahiud , Wang Zhiyong , Chen Guangbo , Huang Shengyun , Chandrasekhar Naisa , Sabaghi Davood , Li Dongqi , Zhang Panpan , Ma Dongling , Brunner Eike , Yu Minghao , Feng Xinliang 
Published: May 2023

AbstractEmerging rechargeable aluminium batteries (RABs) offer a sustainable option for next‐generation energy storage technologies with low cost and exemplary safety. However, the development of RABs is restricted by the limited availability of high‐performance cathode materials. Herein, we report two polyimide two‐dimensional covalent organic frameworks (2D‐COFs) cathodes with redox‐bipolar capability in RAB. The optimal 2D‐COF electrode achieves a high specific capacity of 132 mAh g−1. Notably, the electrode presents long‐term cycling stability (with a negligible ≈0.0007 % capacity decay per cycle), outperforming early reported organic RAB cathodes. 2D‐COFs integrate n‐type imide and p‐type triazine active centres into the periodic porous polymer skeleton. With multiple characterizations, we elucidate the unique Faradaic reaction of the 2D‐COF electrode, which involves AlCl2+ and AlCl4− dual‐ions as charge carriers. This work paves the avenue toward novel organic cathodes in RABs.
Preparation and characterization of polyacrylonitrile/nitrocellulose engineering blend
Authors: Jadhav Pratibha S. , Joshi Girish M. , Deshmukh R. R. 
Published: May 2023

AbstractPolyacrylonitrile (PAN) polymer blends were more in demand due to their wide range of applications. We overcome the restricted low thermal stability and poor strength for deployable blend. In the present study, we prepared PAN and nitrocellulose (NC) polymer blends by solution casting method to overcome the low loss, low dielectric properties as alternative blend for cladding purpose in communication domain. C≡N bond exclusively demonstrated the impact on blending was confirmed by Fourier‐transform infrared spectrophotometer (FTIR) and Raman microscopy measurement. Semicrystalline nature of polymer blends as a function of NC loading was determined by X‐ray diffraction (XRD). Optical polarizing microscopy (OPM) and scanning electron microscopy (SEM) analysis illustrated an appearance of micro flocculated spherulites. Blending ratio of PAN/NC demonstrated the decreased direct band gap identified by Ultraviolet spectroscopy (UV). PAN/NC proved excellent alternative as low dielectric constant and low loss as cladding medium. Blending of NC with PAN exhibited an increased hydrophilicity was confirmed by surface goniometer. Increased thermal stability of polymer blends was mapped by thermogravimetric analysis (TGA). Blend melting temperature and glass transition temperature was increased from 322°C to 334°C and 88°C to 102°C confirmed by Differential scanning calorimetry (DSC) analysis. Thermal conductivity was increased from ~0.13 to ~0.34 W/m. k for PAN/NC determined by Lee's disc probe method. Mechanical properties of blends were measured using universal testing machine (UTM). Tensile strength and Young's modulus was increased up to ~23%, and ~ 56%, whereas elongation break was decreased up to ~71% for PAN/NC blends compared to host PAN system. PAN/NC may suit promising candidate as cladding blend for communication engineering due to low loss and low dielectric constant.
Direct Reaction – One Step Route to Synthesize Lanthanoid‐iodide Formamidinates**
Authors: Guo Zhifang , Halim Md Abdul. , Blair Victoria L. , Deacon Glen B. , Junk Peter C. 
Published: May 2023

AbstractThis paper describes a novel and simple method – direct reaction of lanthanoid metals with equimolar amounts of iodine and a formamidine under ultrasonication as an effective, metal‐based route to lanthanoid(III) diiodide formamidinates, namely I. N,N′‐Bis(2,6‐diisopropylphenyl)formamidinatodiiodidolanthanoid(III) complexes [Ln(DippForm)I2(thf)3] (Ln=La, 1, Ce, 2, Tb, 3, Ho, 4, Er, 5, Tm, 6); II. N,N′‐Bis(2,6‐diethylphenyl)formamidinatodiiodidolanthanoid(III) complexes [Ln(EtForm)I2(thf)3] (Ln=Ce, 7, Nd, 8, Gd, 9, Tb, 10, Dy, 11, Ho, 12, Er, 13, Lu, 14). III. N,N′‐bis(2,6‐dimethylphenyl)formamidinatodiiodidolanthanoid(III) complexes [Ln(XylForm)I2(thf)3] (Ln=Ce, 15, Nd, 16, Gd, 17, Tm, 18, Lu 19); IV. N,N′‐bis(phenyl)formamidinatodiiodidolanthanoid complexes [Ln(PhForm)I2(thf)3] (Ln=Nd, 20, Gd, 21, Er, 22). Compound [Ce(XylForm)2I(thf)2] (23) was also synthesized by the same method except the ratio of I2 to XylFormH was 1 : 4. Divalent N,N′‐bis(2,6‐diisopropylphenyl)formamidinato‐iodido‐lanthanoid(II) complexes [Eu(DippForm)I(thf)4] ⋅ thf (24), [Yb(DippForm)I(thf)3] ⋅ 2DippFormH (25), [Sm(DippForm)I(thf)4] ⋅ thf (26) have also been synthesized by direct reactions of the free metals, iodine and DippFormH. Interestingly, [Sm(DippForm)I2(thf)3] (27) was obtained by the oxidation of [Sm(DippForm)I(thf)4] ⋅ thf (26) on exposure to air. N,N′‐Bis(2,6‐dimethylphenyl)formamidinatoiodidosamarium(II) [Sm(XylForm)I(thf)3]n (28) was also prepared by direct reaction of Sm, iodine and XylFormH (mole ratio of I2: XylFormH=1 : 2). All products have been identified by X‐ray crystallography and all the trivalent complexes [Ln(Form)nI3‐n] (n=1 or 2) are stable to rearrangement.
Synthesis and Studies of Mono‐functionalized Telluradithiasapphyrins and Covalently Linked Porphyrin‐ Telluradithiasapphyrin Dyads
Authors: Ali Md Ashif , Ravikanth Mangalampalli 
Published: May 2023

AbstractA series of mono‐functionalized aromatic 22π telluradithiasapphyrins containing functional groups such as p‐bromophenyl, p‐iodophenyl, p‐nitrophenyl and p‐trimethylsilylethynyl phenyl groups at one of the meso‐positions were synthesized by condensing appropriately functionalized unsymmetrical bithiophene diol and 16‐telluratripyrrane in CH2Cl2 under acid‐catalyzed conditions. To demonstrate the reactivity of mono‐functionalized telluradithiasapphyrins, we synthesized the first examples of covalently linked diphenyl ethyne bridged four novel 18π porphyrin/metalloporphrin‐22π telluradithiasapphyrin dyads by coupling meso‐ethynyl phenyl porphyrin with telluradithiasapphyrin containing meso‐iodophenyl group under Pd(0) coupling conditions followed by metalation of porphyrin unit by treating free base dyad with appropriate metal salts. The dyads were characterized and studied by mass, 1D & 2D NMR, absorption, cyclic voltammetry, fluorescence and DFT techniques. The DFT analysis showed that the porphyrin/metalloporphyrin and sapphyrin units in dyads orient with each other in different angles and Zn(II) porphyrin‐sapphyrin dyad (Zn‐dyad) showed minimum whereas the free base dyad showed maximum angle of deviation. NMR, absorption, and redox studies indicated that the dyads exhibit the overlapping features of their constituted monomers and maintain their individual characteristic features. The steady‐state fluorescence studies revealed that the fluorescence of the porphyrin/metalloporphyrin unit was significantly quenched due to possible energy/electron transfer from the porphyrin/metalloporphyrin unit to non‐emissive sapphyrin unit in dyads.
Adaptive consensus of second‐order nonlinear MASs with aperiodically time‐varying parameters and unknown control directions
Authors: Yi Jiale , Li Jing 
Published: May 2023

AbstractThe problem of adaptive consensus is addressed for a class of second‐order nonlinear multi‐agent systems with aperiodically time‐varying parameters and unknown control directions. Firstly, a new adaptive control approach, so‐called congelation of variables method, is adopted to deal with aperiodically time‐varying parameters which are fast‐varying in an unknown compact set with only their radii known a priori. Secondly, a novel Nussbaum‐type function approach is utilized to address the problem of unknown control directions. It is noteworthy that the control directions investigated in this paper are allowed to be completely unknown and nonidentical, whereas the unknown control directions in the most existing works are assumed to be identical. Thirdly, the unknown nonlinear function in each follower's dynamics is approximated by radial basis function neural network approximation technique. The approximation error, external disturbance in the follower's dynamics, as well as the leader's unknown acceleration dynamics are suppressed as an adaptive robust term, which can alleviate the online computational burden. Then, by designing time‐varying control gains updated adaptively with only local information, a fully distributed adaptive consensus control scheme is designed to guarantee that the multi‐agent systems achieve consensus asymptotically in the presence of unknown aperiodically time‐varying parameters, unknown nonidentical control directions, unknown nonlinearities, and external disturbances. Two simulation examples are provided to validate the effectiveness of the proposed consensus protocol.