bluuebunny/crossref_metadata_2025_split huggingface dataset:
Die Lebenszufriedenheit von Geflüchteten in Deutschland – auch eine Frage von Aufnahmelandbedingungen, Assimilation und Zugehörigkeit?
Authors: Ziegler Paula , Hajji Rahim , Voß Gunnar 
Published: June 2023

Zusammenfassung
Hintergrund
Die Lebenszufriedenheit von Geflüchteten stellt einen Indikator für das subjektive Wohlbefinden dar und gibt einen Einblick, wie die Lebenssituation als Ganzes von dieser vulnerablen Gruppe eingeschätzt wird. Bisherige Untersuchungen zeigen auf, dass u. a. gesundheitliche Belastungen im Zusammenhang mit einer niedrigen Lebenszufriedenheit von Geflüchteten stehen.

Fragestellung
Im Mittelpunkt des Beitrags steht die Frage, inwieweit aus Sicht der Geflüchteten die wahrgenommenen Aufnahmelandbedingungen sowie die Assimilation und die Zugehörigkeit im Zusammenhang mit der Lebenszufriedenheit stehen.

Methodik
Die Frage wird anhand der IAB-BAMF-SOEP-Befragung von Geflüchteten untersucht und die Aufnahmelandbedingungen (Fairnesserfahrung mit Behörden, Gefühl von Willkommensein, Institutionenvertrauen), die Assimilation (Aufenthaltsdauer, deutsche Sprachkenntnisse, Kontakthäufigkeit zu Deutschen im Freundeskreis) und die Zughörigkeit (Anzahl Freund*innen, Zugehörigkeitsgefühl) mittels einer Korrelations- und Regressionsanalyse in Zusammenhang mit der Lebenszufriedenheit ausgewertet.

Ergebnisse
Die bi- und multivariaten Ergebnisse zeigen, dass die Indikatoren für die Aufnahmeland- und die Zugehörigkeitshypothese signifikant mit der Lebenszufriedenheit zusammenhängen.

Schlussfolgerungen
Die Lebenszufriedenheit von Geflüchteten kann vor allem durch die Verbesserung der Aufnahmelandbedingungen und der Förderung von Zugehörigkeitsprozessen gestärkt werden.
Führen Online-Befragungen zu anderen Ergebnissen als persönliche Interviews? Eine Schätzung von Moduseffekten am Beispiel eines Mixed-Mode Surveys
Authors: Liedl Bernd , Steiber Nadia 
Published: June 2023

ZusammenfassungDer zunehmende Einsatz von Online-Befragungen (CAWI) ist ein Trend, der sich im Zuge der COVID-19 Pandemie weiter verstärkte. Der Umstieg von persönlichen Interviews auf Online-Befragungen wirft die Frage nach Moduseffekten auf. Unterscheiden sich die Ergebnisse von Online-Befragungen von jenen auf Basis von Telefoninterviews? Die vorliegende Studie untersucht diese Frage unter Verwendung der Daten aus dem AKCOVID Panel Survey, der ein Mixed-Mode Design aufweist und im ersten Jahr der COVID-19 Pandemie durchgeführt wurde. Die Ergebnisse von Regressionsanalysen für 46 verschiedene Variablen, die für die Zusammensetzung der CAWI- und CATI-Stichproben kontrollieren, zeigen, dass Moduseffekte auf bestimmte Themenbereiche eingegrenzt werden können. Für manche Themen werden signifikante und substantiell bedeutsame Moduseffekte geschätzt (soziales Vertrauen, Zukunftssorgen, finanzielle Problemlagen und Gesundheit). Telefonisch Befragte antworten stärker sozial erwünscht, bringen Sorgen weniger stark zum Ausdruck, schätzen ihre finanzielle Lage, ihren sozialen Status und ihre Gesundheit besser ein, und sie geben an, anderen Menschen mehr zu vertrauen und prosozialer eingestellt zu sein als Online-Befragte. Kaum von Moduseffekten betroffen zeigen sich ‚faktische‘ Fragen nach krisenbedingten Veränderungen des Einkommens ohne Bezug zur finanziellen Lage, Fragen zu Arbeitsbedingungen, familiären Beziehungen oder vielen politischen Einstellungen. Der Beitrag schließt, dass Ergebnisse persönlicher Befragungen aus Zeiten vor der Pandemie oft nicht direkt mit aktuellen Ergebnissen auf Basis von Online-Erhebungen verglichen werden können und weist auf die Bedeutung heterogener Moduseffekte hin, deren systematische Untersuchung und Berücksichtigung als Forschungslücke identifiziert wird.
The Relationship of Parasite Allergens to Allergic Diseases
Authors: Caraballo Luis , Llinás-Caballero Kevin 
Published: June 2023

AbstractPurpose of ReviewHelminth infections modify the natural history of allergic diseases, by either decreasing or increasing their symptoms. Several helminth components are involved in the increasing of the allergic response and symptoms, overcoming the concomitant immunosuppression of helminthiases. However, the role of individual IgE-binding molecules in this process remains to be defined.Recent FindingsWe updated the list of helminth allergens and IgE-binding molecules, their effects on asthma presentation, and their impact on allergy diagnosis. Data from genetic and epigenetic studies of ascariasis are analyzed. A new species-specificA. lumbricoidesallergen has been discovered, with potential use in molecular diagnosis.SummaryMost helminth IgE-binding components are not officially classified as allergens in the WHO/IUIS database, although there is evidence of their influence increasing allergic manifestations. Further immunological characterization of these components is needed to better understand their mechanisms of action and evaluate the ways in which they can influence the diagnosis of allergy.
Th17 cytokines and factors modulating their activity in patients with pernicious anemia
Authors: Kajdaniuk Dariusz , Foltyn Wanda , Morawiec-Szymonik Elżbieta , Czuba Zenon , Szymonik Ewa , Kos-Kudła Beata , Marek Bogdan 
Published: June 2023

Abstract
The effects of specific cytokines produced by T cell subsets (such as Th1, Th2, and newly discovered Th17, Treg, Tfh, or Th22) are diverse, depending on interactions with other cytokines, distinct signaling pathways, phase of the disease, or etiological factor. The immunity equilibrium of the immune cells, such as the Th1/Th2, the Th17/Treg, and the Th17/Th1 balance is necessary for the maintenance of the immune homeostasis. If the balance of the T cells subsets is damaged, the autoimmune response becomes enhanced which leads to autoimmune diseases. Indeed, both the Th1/Th2 and the Th17/Treg dichotomies are involved in the pathomechanism of autoimmune diseases. The aim of the study was to determine the cytokines of Th17 lymphocytes as well as the factors modulating their activity in patients with pernicious anemia. The magnetic bead-based immunoassays used (Bio-Plex) allow simultaneous detection of multiple immune mediators from one serum sample. In our study, we showed that patients suffering from pernicious anemia develop the Th1/Th2 imbalance with a quantitative advantage of cytokines participating in Th1-related immune response, the Th17/Treg imbalance with a quantitative advantage of cytokines participating in Treg-related response, as well as the Th17/Th1 imbalance with a quantitative predominance of cytokines participating in Th1-related immune response. Our study results indicate that T lymphocytes and their specific cytokines play an role in the course of pernicious anemia. The observed changes may indicate the immune response to pernicious anemia or be an element of the pernicious anemia pathomechanism.
Music in an Emergent History of Psychology
Authors: Klempe Sven Hroar 
Published: June 2023

AbstractFrom a historical perspective, ‘psychology’ can be studied from an abundance of angels. Thus, a selected perspective requires some historiographical reflections, but also a conscious awareness of the actual chosen terms that are at stake. In this study, the historiographical perspective follows an emergent understanding of the history, which implies that the actual chosen terms are dynamically contributing to a web of terms, in which all of them may change in more or less unpredictable directions. In line with this, the aspect of music is consciously chosen, as it probably is one of the most ignored aspects of psychology in historical research. Thus, the findings in this study reveal that music as the ’direct factor’ played an overarching role in the nineteenth centuries experimental psychology, but also that the changes in the understanding of music in the early sixteenth century is comparable with the changes the understanding of the soul underwent along with the introduction of the neologism ‘psychology’. In the understanding of both music and the soul the sensational aspects replaced the mathematical.
CircHIPK3 negatively regulates autophagy by blocking VCP binding to the Beclin 1 complex in bladder cancer
Authors: Wang Chong , Liu Tiantian , Wang Jiawei , Cheng Chao , Zhang Ze , Zhang Jingwei , Huang Houbao , Li Yawei 
Published: June 2023

AbstractCircular RNA HIPK3 (circHIPK3) mediates the progression of multiple cancers, including bladder cancer, by regulating cell migration, autophagy and epithelial mesenchymal transition. However, the mechanism by which circHIPK3 regulates autophagy in bladder cancer cells remains unclear. Autophagy is a common self-protection mechanism in eukaryotic cells and is essential for cell survival and death regulation. However, it is unclear whether circHIPK3 affects the level of autophagy in bladder cancer through binding proteins, and the potential regulatory mechanism is unknown. Here, we found that circHIPK3 levels were significantly lower and autophagy-related proteins were significantly upregulated in bladder cancer cells and tissues compared to normal controls. CircHIPK3 downregulation promoted bladder cancer cell proliferation, while circHIPK3 overexpression inhibited proliferation. CircHIPK3 overexpression significantly suppressed autophagy in bladder cancer cells. Overexpression of circHIPK3 did not affect VCP protein expression but inhibited the VCP/Beclin 1 interaction. VCP also stabilized Beclin 1 and promoted autophagy in bladder cancer cells by downregulating ataxin-3. Thus, circHIPK3 may play an important role in bladder cancer by inhibiting VCP-mediated autophagy.
Cultivating Global Scholars: Delving into Chinese Doctoral Students’ Integration Experiences at Finnish Universities Through an Institutional Logics Lens
Authors: Zheng Gaoming , Cai Yuzhuo , Zuo Bing 
Published: June 2023

AbstractInternational doctoral students are key actors in globalized knowledge society. While the value of international doctorates lies in the ability to develop and leverage knowledge across borders and cultures, such competencies can be acquired only when students successfully integrate into the host systems or universities in their international mobility experiences. However, international doctoral students encounter multiple challenges in integration, highlighting a mismatch between their expectations and the practices at the host universities. This article unpacks this mismatch and its causes from an institutional logics’ perspective through interviews with ten Chinese doctoral students and four Finnish supervisors. We found that Chinese students’ expectations of doctoral education were largely influenced by the institutional logics of profession, bureaucratic state, and family, whereas the contexts of Finnish universities were mainly informed by the logics of profession, democratic state, and corporation. The disparity in logic constellations led to the students’ confusion about their role and relations with supervisors. Further, this study shows that reciprocal learning in intercultural supervision can mitigate logics conflicts and create opportunities for innovations in doctoral education in the host university. We call for more efforts to reconcile the logics conflicts that that affect students’ integration, as this could foster organizational innovation.
Fabrication and optimization of itraconazole-loaded zein-based nanoparticles in coated capsules as a promising colon-targeting approach pursuing opportunistic fungal infections
Authors: Adel Shery , Fahmy Rania H. , Elsayed Ibrahim , Mohamed Magdy I. , Ibrahim Reem R. 
Published: June 2023

AbstractItraconazole (ITZ), a broad-spectrum antifungal drug, was formulated into colon-targeting system aiming to treat opportunistic colonic fungal infections that commonly infect chronic inflammatory bowel diseases (IBD) patients due to immunosuppressive therapy. Antisolvent precipitation technique was employed to formulate ITZ-loaded zein nanoparticles (ITZ-ZNPs) using various zein: drug and aqueous:organic phase ratios. Central composite face-centered design (CCFD) was used for statistical analysis and optimization. The optimized formulation was composed of 5.5:1 zein:drug ratio and 9.5:1 aqueous:organic phase ratio with its observed particle size, polydispersity index, zeta potential, and entrapment efficiency of 208 ± 4.29 nm, 0.35 ± 0.04, 35.7 ± 1.65 mV, and 66.78 ± 3.89%, respectively. ITZ-ZNPs were imaged by TEM that revealed spherical core–shell structure, and DSC proved ITZ transformation from crystalline to amorphous form. FT-IR showed coupling of zein NH group with ITZ carbonyl group without affecting ITZ antifungal activity as confirmed by antifungal activity test that showed enhanced activity of ITZ-ZNPs over the pure drug. Histopathological examination and cytotoxicity tests ensured biosafety and tolerance of ITZ-ZNPs to the colon tissue. The optimized formulation was then loaded into Eudragit S100-coated capsules and both in vitro release and in vivo X-ray imaging confirmed the success of such coated capsules in protecting ITZ from the release in stomach and intestine while targeting ITZ to the colon. The study proved that ITZ-ZNPs is promising and safe nanoparticulate system that can protect ITZ throughout the GIT and targeting its release to the colon with effectual focused local action for the treatment of colon fungal infections.
Graphical Abstract
Customer retention and churn prediction in the telecommunication industry: a case study on a Danish university
Authors: Saleh Sarkaft , Saha Subrata 
Published: June 2023

AbstractIn this study, we explore the possible factors affecting churn in the Danish telecommunication industry and how those factors connect with retention strategies. The Danish telecommunication industry is experiencing a saturated market regarding the number of customers, but the number of service providers has increased significantly in recent years. Due to the high costs of acquiring new customers, the telecommunication industry put great emphasis on retaining customers in such an intensely competitive industry. We employ five machine learning algorithms: random forest, AdaBoost, logistic regression, extreme gradient boosting classifier, and decision tree classifier on four datasets from two geographical regions, Denmark and the USA. The first three datasets are from online repositories, and the last one contains responses from 311 students from Aalborg University collected through a survey. We identify key features extracted by the best-performing algorithms based on five performance measures. Based on that, we aggregate all the features that appear important for each dataset. The results demonstrate that customers’ preferences are not aligned. Among the prominent drivers, we find that service quality, customer satisfaction, offering subscription plan upgrades, and network coverage are unique to the Danish student population. Telecommunication companies need to integrate the sociohistoric milieu of the Nordic countries to tailor their retention policies to different consumer cultures.
Tritordeum: a versatile and resilient cereal for Mediterranean agriculture and sustainable food production
Authors: Papadopoulos George , Mavroeidis Antonios , Stavropoulos Panteleimon , Anastasopoulos Vasilios , Beslemes Dimitrios , Tigka Evangelia , Kakabouki Ioanna 
Published: June 2023

AbstractThis review paper provides an in-depth analysis of × Tritordeum [(Ascherson et Graebner)], a novel cereal crop with promising agronomic, nutritional, and economic potential. Through a comprehensive examination of the crop's agronomic characteristics and management requirements, we highlight its adaptability to Mediterranean climates, resilience under changing environmental conditions, and potential applications in the food industry, such as breadmaking and pasta production. We also discuss the role of digital agriculture technologies in optimizing tritordeum cultivation and their potential impact on agricultural practices. Furthermore, we assess the opportunities and challenges associated with tritordeum's integration into the agricultural economy and production systems, emphasizing its potential to contribute to a more sustainable and health-conscious food system. By offering a holistic understanding of tritordeum's attributes, this review serves as a valuable resource for researchers, agronomists, food manufacturers, and policymakers interested in exploring the potential of this innovative cereal grain.
Multiparity Reduces Urethral and Vaginal Pressures Following the Bulboglandularis Muscle Stimulation in Rabbits
Authors: Hernández-Bonilla Cecilia , Zacapa Diego , Zempoalteca René , Corona-Quintanilla Dora Luz , Castelán Francisco , Martínez-Gómez Margarita 
Published: June 2023

AbstractUnlike male mammals showing a well-delimited external urethral sphincter, female mammals have urogenital sphincters shaped by muscles like the urethrovaginal sphincter. Childbirth-related injuries affect morphometry and function of urogenital sphincters in women, which frequently underlies pelvic floor disorders, including stress urinary incontinence and pelvic organ prolapse. The bulboglandularis muscle (Bgm) seems to shape a urogenital sphincter in rabbits. We determined herein the effect of multiparity on urethral and vaginal pressures generated by the Bgm stimulation in age-matched nulliparous and multiparous chinchilla-breed rabbits to stimulate the Bgm with trains of ascending frequencies (from 1 to 100 Hz; 4 s duration each). Subsequently, the Bgm was excised, measured in width, and weighed. Significant differences (P ≤ 0.05) were determined with Mann-Whitney U or Student t-tests or repeated measures two-way ANOVA followed by Tukey tests. Spearman’s partial coefficients were calculated to investigate the correlation between the highest pressure (urethral or vaginal) and the Bgm width. Multiparity reduced the weight and the width in the Bgm origin and medial regions. Urethral and vaginal pressures increased in response to the electrical stimulation of Bgm with frequencies from 20 to 100 Hz. Multiparas showed significant reductions in both types of pressures. We detected a strong correlation (conditioned by multiparity) between the medial Bgm width and the highest vaginal pressure. Our present findings demonstrate that multiparity impairs the function of Bgm, resulting in diminished urethral and vaginal pressures. Furthermore, the significant narrowness of the Bgm was correlated with the vaginal pressure recorded.
Inside out, and upside down, laparoscopic surgery on Situs Inversus Totalis report of 2 cases on IESS Quito-Sur
Authors: Molina Gabriel A. , Jiménez Galo , O Andres Ayala , Di Stefano Marco T. , Suárez Fabián Ramiro , Carvajal Alejandro , Vinueza Dayan , Castillo Soraida , Vintimilla Carol 
Published: June 2023

Abstract
Laparoscopic surgery has become the standard for almost every surgical procedure; the benefits include faster recovery, less pain, and less risk of surgical site infection. Nonetheless, it demands technical knowledge and a high degree of experience from the surgical team to provide patients with the adequate treatment they need. Any variation of the normal anatomy, like situs inversus, can pose a challenge to the surgical team and will need more creativity to perform any surgery accurately and without complications.
We present two situs inversus patients who needed surgical intervention due to cholelithiasis and acute appendicitis. After careful preoperative planning and modifications in the surgical technique, the patients underwent full recovery.

Highlights
Catholic Social Teaching in Practice
Authors: Yuengert Andrew M. 
Published: June 2023

Although the virtues are implicit in Catholic Social Teaching, they are too often overlooked. In this pioneering study, Andrew M. Yuengert draws on the neo-Aristotelian virtues tradition to bring the virtue of practical wisdom into an explicit and wide-ranging engagement with the Church's social doctrine. Practical wisdom and the virtues clarify the meaning of Christian personalism, highlight the irreplaceable role of the laity in social reform, and bring attention to the important task of lay formation in virtue. This form of wisdom also offers new insights into the Church's dialogue with economics and the social sciences, and reframes practical political disagreements between popes, bishops, and the laity in a way that challenges both laypersons and episcopal leadership. Yuengert's study respects the Church's social tradition, while showing how it might develop to be more practical. By proposing active engagement with practical wisdom, he demonstrates how Catholic Social Teaching can more effectively inform and inspire practical social reform.
Evaluating a pilot, structured, face-to-face, antimicrobial stewardship, prospective audit-and-feedback program in emergency general surgery service in a community hospital
Authors: Chan April J. , Tsang Melanie E. , Langford Bradley J. , Nisenbaum Rosane , Wan Michael , Downing Mark A. 
Published: June 2023

Abstract

Background:
Prospective audit and feedback (PAF) is an established practice in critical care settings but not in surgical populations. We pilot-tested a structured face-to-face PAF program for our acute-care surgery (ACS) service.

Methods:
This was a mixed-methods study. For the quantitative analysis, the structured PAF period was from August 1, 2017, to April 30, 2019. The ad hoc PAF period was from May 1, 2019, to January 31, 2021. Interrupted time-series segmented negative binomial regression analysis was used to evaluate change in antimicrobial usage measured in days of therapy per 1,000 patient days for all systemic and targeted antimicrobials. Secondary outcomes included C. difficile infections, length of stay and readmission within 30 days. Each secondary outcome was analyzed using a logistic regression or negative binomial regression model. For the qualitative analyses, all ACS surgeons and trainees from November 23, 2015, to April 30, 2019, were invited to participate in an email-based anonymous survey developed using implementation science principles. Responses were measured using counts.

Results:
In total, 776 ACS patients were included in the structured PAF period and 783 patients were included in the in ad hoc PAF period. No significant changes in level or trend for antimicrobial usage were detected for all and targeted antimicrobials. Similarly, no significant differences were detected for secondary outcomes. The survey response rate was 25% (n = 10). Moreover, 50% agreed that PAF provided them with skills to use antimicrobials more judiciously, and 80% agreed that PAF improved the quality of antimicrobial treatment for their patients.

Conclusion:
Structured PAF showed clinical outcomes similar to ad hoc PAF. Structured PAF was well received and was perceived as beneficial by surgical staff.