bluuebunny/crossref_metadata_2025_split huggingface dataset:
Towards a set of competencies in palliative care nursing in Spain: what’s getting in the way of consensus?
Authors: Guanter-Peris Lourdes , Alburquerque-Medina Eulàlia , Solà-Pola Montserrat , Consuegra Margarida Pla i 
Published: May 2023

Abstract
Background
Spain currently lacks a competency framework for palliative care nursing. Having such a framework would help to advance this field in academic, governmental, and health management contexts. In a previous phase of research, 98 proposed competencies were presented to a sample of palliative care nurses. They accepted 62 of them and rejected 36.
Methods
In the present phase, we conducted a qualitative exploratory study using consensus techniques with two modified nominal groups to gain an understanding of why the 36 competencies had been rejected. Twenty nurses from different areas of palliative care (direct care, teaching, management, research) participated. We conducted a thematic analysis using NVivo12 to identify meaning units and group them into larger thematic categories.
Results
Participants attributed the lack of consensus on the 36 competencies to four main reasons: the rejection of standardised nursing language, the context in which nurses carry out palliative care and other factors that are external to the care itself, the degree of specificity of the proposed competency (too little or too great), and the complexity of nursing care related to the end of life and/or death.
Conclusions
Based on the results, we propose reparative actions, such as reformulating the competencies expressed in nursing terminology to describe them as specific behaviours and insisting on the participation of nurses in developing institutional policies and strategies so that competencies related to development, leadership and professional commitment can be implemented. It is essential ​​to promote greater consensus on the definition and levels of nursing intervention according to criteria of complexity and to advocate for adequate training, regulation, and accreditation of PC expert practice. Locally, understanding why the 36 competencies were rejected can help Spanish palliative care nurses reach a shared competency framework. More broadly, our consensus methodology and our findings regarding the causes for rejection may be useful to other countries that are in the process of formalising or reviewing their palliative care nursing model.
ATM-Mediated Translocation of RanBPM Regulates DNA Damage Response by Stabilizing p21 in Non-Small Cell Lung Cancer Cells
Authors: Deng Tanggang , Xie Lin , Xiaofang Chen , Zhang Zhenbin , Xiao Yugang , Peng Yuchong , Yin Linglong , Fu Yongming , Li Xiong 
Published: May 2023

Abstract
Non-small cell lung cancer (NSCLC) is the leading cause of cancer-induced deaths around the world, and platinum-based chemotherapy remains a standard-of-care for most patients with advanced NSCLC. DNA damage response (DDR) induced by platinum or Etoposide activated a panel of cell cycle-regulatory proteins including p21 through p53 pathway. In this present study, we found that the level of p21 or RanBPM is lower in NSCLC than non-malignant tissues and has a highly positive correlation, which is positively correlated with the survival of patients. We further revealed that RanBPM protein physically interacts with p21, RanBPM deubiquitinates p21 by recruiting a deubiquitinase USP11 to maintain protein stability of p21. Furthermore, RanBPM regulates DNA damage response (DDR) in a p21-dependent manner, and DNA damage promotes the translocation of RanBPM into the nucleus and regulates p21 protein stability through ATM-mediated pathways. We revealed a novel mechanism of p21 protein stability regulated by RanBPM, and the novel roles of RanBPM in the regulation of DDR.
Recombined Egg Yolk Granules with Controllable Particle Sizes for Quercetin Delivery - A Structure-Activity Relationships Study
Authors: Li Teng , Yao Junze , Everett David W. , Hou Yilin , Pan Zhongshun , Su Huanhuan , Fu Yuying 
Published: May 2023

Abstract
The effect of particle size on physicochemical stability, bioaccessibility, and bioactivity of bioactive compounds is important in the design of delivery systems. It is challenging to control the size of delivery systems without altering chemical composition. In the present study, the re-assembly of dissociated egg yolk granules was modulated by Ca2+ to produce recombined granules with controlled hydrodynamic diameter (Dh). Quercetin was selected as a representative bioactive compound encapsulated within recombined granules (Gra-Que). Encapsulation efficiency and loading efficiency increased with an increase in Dh until phase separation occurred at 250 µg/mL Ca2+. The thermal and photochemical stability of Gra-Que increased as Dh increased, whereas samples with the smallest Dh demonstrated the highest storage stability. Gra-Que with an intermediate Dh had the highest bioaccessibility due to a balance between the protection of quercetin and susceptibility to digestion. Smaller samples had higher bioactivity due to higher cellular uptake and greater susceptibility to digestion.
Examining Assessment Practices of K-12 Public School Teachers in Maguindanao Province
Authors: Mohammad Nhelbourne , Ma Hongliang , Akrim Akrim 
Published: May 2023

Abstract
The Philippines was categorized in the lowest 70s in the 2018 PISA results among the 79th participating countries. Consequently, the authors believed the key factor of assessment is to improve teaching practices and students’ academic achievement; thus, this study aimed to examine the teachers’ assessment practices by employing a modified Assessment Practices Inventory (API) scale. The scale was tested with 42 secondary school teachers to determine its preliminary validity and reliability; a Cronbach alpha of .736 indicates acceptable reliability. The study employed 194 respondents of public high school teachers. According to this result, educators routinely assess to determine lesson progression and fine-tune student learning. Besides, some teachers need to gain knowledge of establishing validity and reliability. Hence, it is extremely urged that the K-12 teachers in Maguindanao, Philippines, must attend seminars to improve their skills in formulating questions of higher thinking skills.
Effect of Amount of Daily Water Intake and Use of Moisturizer on Skin Barrier Function in Healthy Female Participants
Authors: Seol Jung Eun , Cho Gyeong Je , Jang Seung Hee , Ahn Sang Woo , Hong Seong Min , Kim Jong Uk , Park So Hee , Kim Hyojin 
Published: May 2023

Abstract
method
additional water intake (H1, L1), moisturizer (H2, L2), both (H3, L3), and control (H4, L4). Transepidermal water loss (TEWL) and stratum corneum hydration (SCH) were measured at baseline during the 2nd and 4th week. A total of 50 participants were enrolled (H: 24, L: 26) and 43 participants completed the study (H: 22, L: 21). At baseline, group H1–4 showed tendency of higher SCH value in the forehead, left cheek, and left forearm compared to group L1–4. TEWL of group H1 was significantly lower than that of group H4 at the 4th week (p = 0.012). SCH of group L2 was higher than those of group L1 (p = 0.014) and group L4 (p = 0.000), from the 2nd week. The results suggest that the degree of water intake and moisturizer application may be related to improved skin barrier function. Also, in the short duration of time, the application of additional moisturizers had more favorable impact on skin hydration as compared to additional water intake.
EggCountAI: A Convolutional Neural Network Based Software for Counting of Aedes Aegypti Mosquito Eggs
Authors: Javed Nouman , López-Denman Adam J. , Paradkar Prasad N. , Bhatti Asim 
Published: May 2023

Abstract
1. Mosquito-borne diseases exert a huge impact on both animal and human populations, posing substantial health risks. Established practices, such as long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS), are proving inadequate for controlling mosquito-borne diseases. The behavioural fitness traits of mosquitoes, such as locomotion and fecundity, are crucial factors that influence the spread of diseases. Technological advancements, including Artificial Intelligence (AI), have provided various methods that can be used to monitor these traits effectively.
2. This study presents EggCountAI, a Mask RCNN (Region-based Convolutional Neural Network) based free automatic egg counting tool for Aedes aegypti mosquitoes, the primary vector of several life-threatening diseases, including dengue fever. EggCountAI takes a folder containing egg strip images as input and counts eggs in all the images without any supervision. EggCountAI also provides flexible filtration, considering the possibility of unwanted impurities of different sizes on images. The performance of the EggCountAI was tested using microscopic and macroscopic images of eggs laid on a paper strip. To validate EggCountAI's capability, the results were also compared with two commonly employed tools, ICount and MECVision, confirmed by manually counting all eggs on strips.
3. The results obtained from EggCountAI highlight its remarkable performance, achieving an overall percentage accuracy of 98.88% for micro images and 96.06% for macro images. EggCountAI also significantly outperformed two currently available tools, ICount and MECVision, in performance. The overall accuracy of ICount was 81.71% for micro images and 82.22% for macro images, while the overall accuracy of MECVision was 68.01% for micro images and 51.71% for macro images. The superior performance of the EggCountAI was most evident when handling overlapping or clustered eggs.
4. The use of such tools can benefit in establishing the role of mosquito fitness changes to improve epidemiological models and implement new mosquito management strategies. Introducing such tools can also help to reduce transmission by vectors quicker, by finding the mosquitoes' preferred sites to lay their eggs. Though the focus of this AI-based tool is to count the number of eggs, this tool can be modified to track other mosquito fitness parameters such as egg sizes.
Effect of gadolinium trioxide on anode performance of aluminum-air batteries
Authors: Zhu Yiming , Zhao Tianyu , Yu Xiaohua , ZHU Yanli , SHEN Qingfeng , LI Rongxing , XIE Gang 
Published: May 2023

Abstract
The self-corrosion rate was analyzed by polarization, impedance, and constant current discharge tests, the anode energy density was calculated by continuous constant current discharge at a current density of 10-180mA/cm2, and the surface morphology of the electrode was analyzed by scanning electron microscope (SEM) to study the effect of Gd2O3 additives on the aluminum anode performance of aluminum-air batteries in alkaline solution. The positive corrosion potential shift of the polarization curve, the decrease of corrosion current, the decrease of R1 (charge transfer internal resistance) in impedance test, the decrease of hydrogen evolution rate, and the decrease of pitting pits in surface topography analysis showed that the addition of Gd2O3 particles to the pure aluminum anode affected the charge transfer on the anode surface, improved its corrosion resistance, and inhibited the occurrence of hydrogen evolution reaction. The addition of Gd2O3 to pure aluminum has a positive effect on the performance of the battery anode material, which makes the corrosion resistance of the anode material significantly improved, and the discharge is stable and uniform, which is more suitable as an anode material for aluminum-air batteries.
Autoencoder Convolutional Neural Network-Based Brain Tumor Segmentation
Authors: S Singaravelan , S Balaganesh , P Gopalsamy , R Arun 
Published: May 2023

Abstract
The process of retrieving the affected brain parts from the input images to ensure proper treatment is known as brain tumour segmentation. It was done in the previous research utilizing the FCNN-Brain tumour segmentation method. in this work, However, the accuracy of this method is slightly lower, which is addressed and resolved by introducing the Auto Encoder Convolutional Neural Network-based Brain Tumour Segmentation method (AECNN-BTS); and Pre-processing is done using a modified Gabor filter. And feature extraction is done using modified discrete wavelet transform. Following feature extraction, the fitness mutant particle swarm optimization approach is used to choose features. The classification is done utilizing the classified namely auto encoder convolutional neural network based on these features. Finally, images affected by a brain tumour are segmented using a modified k means integrated OTSU segmentation method. The whole evaluation of the research work is performed in a Matlab simulation environment, demonstrating that the suggested method is more efficient than previous methodologies.
Visualization Analysis and Quality Evaluation of the International Communication of TCM Classics
Authors: Xin XIONG , Qi Fan 
Published: May 2023

Abstract
The international communication of TCM classics can better enable the international community to recognize China's excellent traditional medicine culture, promote the integration of TCM into the international medicine system, and gain more shares of international discourse. This paper uses CiteSpace to scientifically analyse the number, keywords, institutions, and authors of the literature published from 2000 to 2022 on the China National Knowledge Infrastructure (CNKI) and Web of Science (WOS) for the international communication of TCM classics and utilizes AMSTAR2, a quality evaluation tool for interpretation. In this paper, several measures are proposed to solve the problems in the international communication of TCM classics, such as broadening research fields, focusing on theory construction, strengthening interdisciplinary cooperation, enhancing academic cooperation and improving translation quality.
The Impact of Radiolabeled Nanomaterials
Authors: Ortega Pijeira Martha Sahylí , Gomes da Silva Natália Cristina , Rebelo Alencar Luciana Magalhaes , Ricci-Junior Eduardo , Santos-Oliveira Ralph 
Published: May 2023

Abstract:
Nanotechnology has changed the world, with a great impact on industry and
medicine. In this commentary, we discuss the importance of radiolabeled nanomaterials for
the construction of theranostic, imaging and therapeutic agents in order to pave the future of
medicine.
PENYUSUNAN MODUL ELEKTRONIK PENYAKIT SISTEM PENCERNAAN PADA MANUSIA SEBAGAI BAHAN PENGAYAAN BAGI SISWA KELAS XI
Authors: Atiqoh Arin Azzah , Suhandoyo Suhandoyo 
Published: May 2023

Penelitian ini bertujuan untuk (1) menyusun modul elektronik penyakit sistem pencernaan pada manusia yang dapat digunakan secara mandiri sebagai bahan pengayaan siswa kelas XI; (2) mengetahui kualitas modul pengayaan elektronik penyakit sistem pencernaan pada manusia berdasarkan ahli materi, ahli media, dan guru biologi. Penelitian ini merupakan penelitian Research and Development (RD) dengan model ADDIE, namun dibatasi hanya sampai pada tahap ADD (Analysis, Design, Development). Hasil penelitian menunjukkan bahwa (1) modul elektronik penyakit sistem pencernaan pada manusia sebagai bahan pengayaan siswa kelas XI MIPA dikembangkan menjadi modul elektronik dalam bentuk flipbook dengan melalui website online, yaitu fliphtml5.com. dengan link modul adalah sebagai berikut Modul Pengayaan Elektronik Penyakit Pada Sistem Pencernaan Manusia untuk Siswa Kelas XI MIPA (fliphtml5.com) (2) modul elektronik penyakit sistem pencernaan yang disusun layak digunakan dan dikembangkan pada tahap selanjutnya, yaitu IE (Implementation, Evaluation).
PENGEMBANGAN VLab UJI ZAT MAKANAN DENGAN MODEL DISCOVERY LEARNING UNTUK MENGEMBANGKAN KETERAMPILAN PROSES SAINS SISWA KELAS XI SMA
Authors: Putrisari Desy , Subiantoro Agung Wijaya 
Published: May 2023

Penelitian bertujuan untuk (1) untuk mengembangkan prototipe aplikasi media Virtual Laboratory Uji Zat Makanan, (2) mengetahui kelayakan dari media Virtual Laboratory Uji Zat Makanan dengan model pembelajaran discovery learning sebagai media pembelajaran biologi untuk siswa SMA kelas XI IPA. Penelitian ini merupakan penelitian dan pengembangan (RD) dengan model pengembangan ADDIE yang hanya dilakukan sampai tahap Development (ADD). Subjek dalam penelitian ini ialah dua ahli materi, dua ahli media, dua guru Biologi SMA, dan 28 siswa SMA kelas XI IPA. Pengumpulan data menggunakan instrumen review berupa angket skala Likert. Teknik analisis data menggunakan analisis deskriptif kuantitatif. Penelitian ini menghasilkan produk berupa aplikasi Virtual Laboratory Uji Zat Makanan untuk siswa SMA kelas XI IPA pada materi pokok sistem pencernaani. Berdasarkan hasil penilaian ahli dan praktisi, serta tanggapan dari 28 siswa aplikasi Virtual Laboratory Uji Zat Makanan memenuhi kriteria minimal baik sehingga dapat dinyatakan layak untuk dikembangkan lebih lanjut.
PENGGUNAAN E-LKPD BERBASIS MASALAH TERHADAP PENINGKATAN KETERAMPILAN BERPIKIR KRITIS PESERTA DIDIK PADA MATERI SISTEM EKSKRESI KELAS XI DI SMA NEGERI 1 PANGKALPINANG
Authors: Shafira Istu Hanan , Suratsih Suratsih 
Published: May 2023

Penelitian ini bertujuan untuk mengetahui penggunaan E-LKPD berbasis masalah terhadap peningkatan keterampilan berpikir kritis peserta didik pada materi sistem ekskresi. Penelitian ini termasuk dalam jenis penelitian kuasi eksperimen dengan menggunakan nonequivalent control group design. Populasi dalam penelitian ini adalah seluruh peserta didik kelas XI MIPA di SMA Negeri 1 Pangkalpinang. Sampel penelitian yang diambil sebanyak dua kelas yaitu kelas XI MIPA 4 sebagai kelas eksperimen dan kelas XI MIPA 1 sebagai kelas kontrol. Pemilihan sampel tersebut menggunakan teknik purposive sampling. Data keterampilan berpikir kritis dikumpulkan menggunakan tes berbentuk uraian. Teknik analisis data dilakukan dengan uji Independent Sample T-test dan uji Effect Sizes. Hasil penelitian menunjukkan bahwa pada kelas eksperimen diperoleh rata-rata nilai posttest sebesar 66,67 sedangkan rata-rata posttest kelas kontrol sebesar 56,87. Hasil Independent T-test menunjukkan nilai Sig (2-tailed) sebesar 0,021 0,05 sedangkan hasil uji Effect Sizes diperoleh nilai cohen’s d sebesar 0,6 dengan persentase sebesar 73%. Hal ini menunjukkan bahwa E-LKPD berbasis masalah memberikan pengaruh yang signifikan terhadap keterampilan berpikir kritis peserta didik dengan besaran efek yang diberikan termasuk dalam kategori sedang.
Pengembangan Video Pembelajaran Uji Urin Indikasi Kelainan pada Sistem Ekskresi Kelas XI SMA
Authors: Prihatiningtyas Arifah Siwi , Triatmanto Triatmanto 
Published: May 2023

Tujuan penelitian yang dilakukan mengetahui kelayakan media pembelajaran berbasis video pada materi materi uji urin indikasi kelainan sistem ekskresi kelas XI SMA. Penelitian ini merupakan Research and Development atau penelitian dan pengembangan dengan model pengembangan 4D (Define, Design, Develop, dan Disseminate). Subjek penelitian yaitu 2 ahli media, 2 ahli materi, 2 praktisi, dan peserta didik kelas XI SMA berjumlah 20 orang. Objek penelitian berupa video pembelajaran uji urin indikasi kelainan sistem ekskresi kelas XI SMA. Teknik pengumpulan data dilakukan dengan metode observasi tidak langsung, wawancara tidak terstruktur, dan angket/ kuesioner. Teknik analisis data penelitian ini menggunakan analisis deskriptif kualitatif. Hasil penelitian Berdasarkan hasil review dari 2 ahli media, 2 ahli materi, 2 praktisi dan uji keterbacaan oleh 20 peserta didik serta setelah dilakukan revisi akhir menunjukkan hasil bahwa video pembelajaran uji urin indikasi kelainan sistem ekskresi ditinjau dari beberapa aspek penilaian telah memenuhi kriteria penilaian selanjutnya dapat dilanjutkan ke uji pada tahapan diseminasi atau penyebaran. The purpose of the study was to determine the feasibility of video-based learning media on urine test material indicating abnormalities of the excretory system in class XI SMA. This research is a Research and Development or research and development with a 4D development model (Define, Design, Develop, and Disseminate). The research subjects were 2 media experts, 2 material experts, 2 practitioners, and 20 high school class XI students. The object of the research was a video of a urine test learning indication of an excretory system abnormality in class XI SMA. Data collection techniques were carried out using indirect observation methods, unstructured interviews, and questionnaires/questionnaires. The data analysis technique of this research used descriptive qualitative analysis. Research results Based on the results of a review from 2 media experts, 2 material experts, 2 practitioners and a readability test by 20 students and after the final revision showed the results that the urine test learning video was an indication of an excretory system abnormality in terms of several aspects of the assessment, it had met the next assessment criteria. proceed to the test at the stage of dissemination or dissemination.
Hubungan Hasil Belajar Siswa terhadap Karakter Kemandirian di SMP Negeri 09 Muaro Jambi
Authors: Julia Hastirani Rahma , Prima Yeni Niza 
Published: May 2023

Tujuan dari penelitian ini adalah untuk menganalisis dan mengetahui hubungan antara hasil belajar terhadap karakter kemandirian belajar siswa. Pendekatan yang digunakan dalam penelitian ini adalah pendekatan kualitatif dengan metode deskriptif atau lebih tepatnya Deskriptif Asosiatif. Instrumen yang digunakan pada penelitian ini ialah lembar observasi berupa angket karakter kemandirian dan soal pilihan ganda yang berjumlah 30 soal terhadap mata pelajaran IPA yang sudah di validasi oleh validator ahli. Berdasarkan tabel dan data hasil tersebut dapat dilihat bahwa nilai signifikansi dari hasil perhitungan menunjukkan bahwa pada variabel angket kemandirian belajar 0,200 0,05 dan pada variabel hasil belajar 0,200 0,05. Hasil perhitungan tersebut menunjukkan bahwa data dari kedua variabel berdistribusi normal. Pada uji korelasi, hasil perhitungan menunjukkan nilai r hitung 0,035 0,05 pada kelas 8B dan pada kelas 8C nilai r hitung 0,040 0,05. Berdasarkan nilai koefisien korelasi dan nilai sig, dapat di sebutkan bahwa hipotesis yang diajukan yaiutu adanya hubungan positif dan signifikan antara kemandirian belajar dengan hasil belajar siswa kelas 8B dan 8C SMPN 09 Muaro Jambi dapat diterima dengan tingkat korelasi atau hubungannya rendah.
Proses Berpikir Parsial dan Berpikir Utuh pada Kesalahan Pemahaman Siswa
Authors: Mirah Liani Ahyani , Nusantara Toto 
Published: May 2023

Penelitian ini bertujuan untuk melihat proses berpikir siswa pada kesalahan pemahaman konsep materi pecahan. Pendekatan penelitian ini tergolong dalam deskriptif kualitatif. Subjek dalam penelitian ini adalah siswa SMP kelas VII di SMP Mualimin. Hasil penelitian ini menunjukkan bahwa siswa mengalami kesalahan pemahaman, siswa menanggap bahwa pecahan yang ditunjukkan pada gambar soal adalah dengan alasan terdapat 4 bagian dari 4 bagian tersebut terdapat 3 bagian yang diarsir sehingga menyatakan . Alasan yang diberikan kurang tepat karena pada soal ini konsep yang dibahas adalah part whole congruent part (bagian suatu daerah yang bagian-bagiannya sama besar). Proses berpikir ini menganggap bahwa unsur-unsur yang saling berdekatan dalam bidang pengamatan akan dipandang sebagai satu bentuk tertentu, ini berdasarkan hukum Gestalt yaitu hukum kedekatan (proximity). Subjek mengganggap bahwa ada kedekatan bagunan yang diarsir sama bentuknya, yang ditunjukkan pada gambar adalah 3/4.