bluuebunny/crossref_metadata_2025_split huggingface dataset:
The practice of application and features of the control of oligosaccharides in the production of specialized food products. A review
Authors: Yurova E. A. , Ananyeva N. V. 
Published: January 2023

Functional oligosaccharides include various groups of carbohydrates with the biological activity — an ability to modulate gut microbiota due to the prebiotic, anti-adhesive and anti-inflammatory activities. The unique properties of oligosaccharides explain a wide spectrum of their use in the dairy industry: from food ingredients for imitation of the prebiotic activity of human milk oligosaccharides in infant dry milk mixtures to structuring additives, replacers of sugar and fat. When choosing oligosaccharides for inclusion into dairy products, their biological activity and technological properties that depend on a source and method for extraction of these compounds are assessed. Fructooligosaccharides, galactooligosaccharides, xylooligosaccharides and pectic oligosaccharides have been most widely used. When developing recipes of products with stated biological effectiveness, it is necessary to remember that consumption of large amounts of substances with prebiotic properties can lead to the gastrointestinal disorder, which requires introducing into practice the control of the oligosaccharide quantitative content in the product composition. The aim of this review is analysis of possibilities of using oligosaccharides in production of specialized milk-based food products and methods for controlling quality, safety and effectiveness of inclusion of such products into a diet. The review considers the existing methods for quantitative identification of oligosaccharides included in the composition of dairy products as functional ingredients. The emphasis is made on the limitations of the introduction of the developed analytical methods into routine practice of the oligosaccharide control, which is linked with the complexity and multicomponent nature of the food matrix under study. The necessity of the further improvement of methods for quantitative identification of functional oligosaccharides in foods is shown.
Studying an effect of thermal treatment methods on physico-chemical properties of beef depending on aging technology
Authors: Gurinovich G. V. , Khrenov V. A. , Patrakova I. S. , Patshina M. V. 
Published: January 2023

Modern methods for aging and thermal treatment facilitate an improvement in beef sensory properties. The aim of the research was to study an effect of different types of thermal treatment on quality of steaks from dry-aged beef. Steaks were obtained from the rib cut from carcasses of grain-fed young bulls; aging duration was 35 days (temperature 0–1 ºС, air relative humidity 74–75%). Aging duration in the control sample was five days (temperature 0–4 ºС, air relative humidity 80–85%). The methods for thermal treatment were as follows: sous vide cooking at 58 ºС, grill heating at 250 ºС, sous vide cooking in combination with grill treatment. During processing, the following parameters were controlled: weight loss by the direct method, hydrophobicity of myofibrillar proteins by the reaction with bromophenol blue, soluble collagen by the method of acid hydrolysis with determination of oxyproline, mass fraction of moisture and fat by the method from one analytical unit, sensory properties by the reference method. According to the data obtained, minimal losses (6.8%) were noticed upon sous vide cooking of dry-aged beef steaks. In combined heating and dry heating on grill, they increased by 6.1% and 12%. More significant weight losses were observed in beef steaks with aging time of five days upon any tested treatment types. For dry-aged beef steaks treated by sous vide and combined heating, a higher content of soluble collagen compared to other samples was established. The results of measuring mass fraction of moisture and fat indicate an increase in the nutritional value of dry-aged beef steaks. According to the total data obtained with consideration for the results of sensory evaluation, dry-aged beef steaks subjected to sous vide cooking with the following short-term dry heating on grill have higher quality.
Computational Analysis, in silico Functional Annotation and Expression of Recombinant mycobacterium, PE_PGRS Protein Biomarkers
Authors: Moodley-Reddy Avanthi , Chiliza Thamsanqa Emmanuel , Pooe Ofentse Jacob 
Published: January 2023

Background
Over the years, there have been many advances made within the treatment and diagnosis of Mycobacterium Tuberculosis (Mtb). In recent times, the rise of drug resistance has led to higher mortality rates specifically in poorer countries. There is an urgent need for novel treatment regimens to work against Mtb. A gene family, found in Mtb, PE_PGRS proteins shows potential as a drug target in its life cycle; to prevent the activation of latent Mtb to active Mtb. In silico functional annotations of these proteins are cost-effective and avoid wasting effort on a protein with no potential.

Method
Previous studies indicated that the PE_PGRS showed potential for further research. The protein biomarkers which showed the most promise was identified as PE_PGRS17, PE_PGRS31, PE_PGRS50 and PEPGRS54. The sequences of these proteins were searched on the Mycobrowser software. Results were designed by entering these sequences into various computational algorithms. PE_PGRS17 showed characteristics of a potential vaccine candidate. Considering this result, expression profiling and purification was conducted on the recombinant PE_PGRS17 Mtb protein biomarker.

Results and Discussion
The results were calculated using various online software algorithms. Many characterizations and other aspects were predicted to understand the stability, localization, and function of these proteins. All the proteins are estimated to produce an immune response or be involved in the process of immunity. The expression condition of the recombinant PE_PGRS17 was optimised, and purification strategy achieved using E.coli as a host cell. These findings make these proteins, specifically PE_PGRS17, popular for further scientific study.

Conclusion
The predicted structures, protein-protein interaction and antigenic properties of the proteins estimate whether the protein can be used for further studies specifically as drug/vaccine targets. Ultimately PE_PGRS17 is seen as the most stable according to its structure and it holds more promise as a key factor to tuberculosis studies.
Borderline Personality Disorder In Pandemic Situation In Indonesia
Authors: Wibhowo Christin , Sanjaya Ridwan 
Published: January 2023

Background
Individuals with borderline personality disorder (BPD) feel more stressed than others during the pandemic. Several researchers conducted from the West have concluded that the factors causing BPD consist of neurobiology, childhood trauma, attachment coping and social support. These results were different from the research conducted in Indonesia. Therefore, it’s necessary to re-examine the factors causing BPD as knowing the causative factors of BPD is very important for prevention.

Objectives
This research had two stages: (1) Mapping the factors causing BPD (2) Knowing the proactive coping used by participants

Method
Data collection in Study 1 used four scales: BPD scale, Childhood Adversity, Proactive Coping, and Social Support. There were 180 participants in this study. Hypothetical analysis was performed with Structural Equation Modeling (SEM) .
Online interviews were conducted in Study 2 with six participants who were previously known to have BPD based on the results of the BPD scale

Result
Study 1: Childhood adversity, social support, and proactive coping play a role in BPD. However, not all factors play a direct role in BPD. Proactive coping (PC) had a direct role in BPD. Study 2: The participants do not use proactive coping but use defense mechanisms, such as repression, regression and denial. They tend to be more depressed so they don’t use proactive coping as usual.

Conclusion
Childhood adversity, social support, and proactive coping play a role in BPD. However, only PC had a direct role. The better the PC owned, the fewer BPD criteria individuals have. The coping strategies participants carried out before the pandemic were different from those applied during the pandemic.
Evaluating the Effects of the Supportive Parenting App on Infant Developmental Outcomes: Longitudinal Study
Authors: Shorey Shefaly , Chong Yap Seng , Shi Luming , Chua Jing Shi ,   Thilagamangai, Mathews Jancy , Lim Siew Hoon , Du Ruochen , Chan Yiong Huak , Tan Thiam Chye , Chee Cornelia , Law Evelyn 
Published: January 2023

Background
Previous studies have investigated the various effects of parenting on infant developmental outcomes. In particular, parental stress and social support have been found to significantly affect the growth of the newborn. Although many parents today use mobile apps to obtain more support in parenting and perinatal care, few studies have examined how these apps could affect infant development.

Objective
This study aimed to examine the effectiveness of the Supportive Parenting App (SPA) in improving infant developmental outcomes during the perinatal period.

Methods
This study adopted a 2-group parallel prospective longitudinal design and recruited 200 infants and their parents (N=400 mothers and fathers). The parents were recruited at 24 weeks of gestation for a randomized controlled trial conducted from February 2020 to July 2022. They were randomly allocated to either the intervention or control group. The infant outcome measures included cognition, language, motor skills, and social-emotional development. Data were collected from the infants when they were aged 2, 4, 6, 9, and 12 months. Linear and modified Poisson regressions were used to analyze the data to examine between- and within-group changes.

Results
At 9 and 12 months post partum, the infants in the intervention group were found to have better communication and language skills than those in the control group. An analysis of motor development revealed that a larger proportion of the infants in the control group fell under the at-risk category, where they scored approximately 2 SDs below the normative scores. The control group infants scored higher on the problem solving domain at 6 months post partum. However, at 12 months postpartum, the infants in the intervention group performed better on cognitive tasks than those in the control group. Despite not being statistically significant, the intervention group infants were found to have consistently scored better on the social components of the questionnaires than the control group infants.

Conclusions
Overall, the infants whose parents had received the SPA intervention tended to fare better in most developmental outcome measures than those whose parents had received standard care only. The findings of this study suggest that the SPA intervention exerted positive effects on the communication, cognition, motor, and socioemotional development of the infants. Further research is needed to improve the content and support provided by the intervention to maximize the benefits gained by infants and their parents.

Trial Registration
ClinicalTrials.gov NCT04706442; https://clinicaltrials.gov/ct2/show/NCT04706442
Development of Gastro-floating drug delivery system by 3D Printing: Impact of formulation and design on the release profile of Baclofen
Authors: Abdulkhaleq Nuha Mohammed , Ghareeb Mowafaq M. 
Published: January 2023

Objectives: Baclofen is a skeletal muscle relaxant with a short half-life and a narrow absorption window in the upper part of the gastrointestinal tract, and this study aims to formulate a sustained-release tablet of baclofen and 3D printing of gastro-floating device and study the effect of various polymers and device design on the release profile of baclofen.
Method: Firstly, four formulas were produced through the hot-melt extrusion and direct compression of the extrudate to produce 30 mg baclofen tablets, then four gastro-floating devices (A, B, C, and D) were designed with two air pockets to enable the floating of the device and have drug-releasing windows with total surface area 4, 10, 20, and 40 mm2 respectively, for drug release. 3D printing of the devices was done by an FDM printer and the tablets were inserted into each device and test it for drug release.
Results: Decreasing the surface area of the drug releasing windows revealed a significant reduction in the dissolution of baclofen irrespective of the type of polymers and useful for sustained release formulation but may be associated with lag time. Devices with one and two releasing windows (Device B and C respectively) sometimes revealed similar dissolution profiles and this related to the position of the window regarding the surface of the dissolution media. Device D with four windows and a 40 mm2 surface area was found to produce more reliable results. F3 which contains Eudragit RS-100 as the main polymer showed sustained release in device D where the complete dissolution of the drug occurred in 12 hours, and the gastro-floating device remained floating all the time and was assayed for drug content, FT-IR, and DSC study.
Conclusion: Hot-melt extrusion was successfully employed to produce sustained release tablets of baclofen. FDM 3D printers are considered a potential tool to produce gastro-floating devices with the required design and release profile.
Job performance predictors in a group of information and communication technology specialists
Authors: Berga Linda , Austers Ivars 
Published: January 2023

Based on the theory of person-environment fit, non-cognitive predictors of job performance were studied in a group of information and communication technology (ICT) specialists. From various potential job and training performance predictors seven psychological attributes (personality, vocational interests, grit, growth mindset, self-efficacy, goal orientation and resistance to change) were chosen and tested as predictors of job performance ratings, as provided by either the supervisor or the study participant. The results indicate that grit, vocational interests, and resistance to change predict job performance in this group of ICT specialists. This study adds to the scientific literature of grit and vocational interests as non-cognitive predictors of job performance. Implications for practice include the recommendation of using grit and vocational interests in personnel management processes such as personnel selection or placement.
Relationship Between Family History Knowledge, Identity Style and Resilience of 16-19 Year Old Adolescents
Authors: Siliniece Sandra , Miltuze Anika 
Published: January 2023

The aim of the present study was to examine the relationships between family history knowledge, identity style and resilience of 16–19 year old adolescents. Participating in the study were 110 adolescents (75% female, 25% male), ages 16–19 year (M = 17,62; SD = 1,23). They completed the Do You Know scale (Duke, Lazarus & Fivush, 2008), the Identity Style Inventory (Berzonsky, 1992) and the Resilience Scale for Adults (Friborg et al., 2005). The results showed positive associations between knowledge of family history and informational, normative identity style and resilience; and negative association with diffuse identyty style. Knowledge of family history predicted identity style and resilience, with the exception of the social resource factor ratings. Relationships with mother predicted the resilience factors of self-perception, family cohesion and social resources. The internal resource factor of resilience provided partial mediation between knowledge of family history and informative identity style.
Childhood Trauma, Trauma Symptoms, Family Fat Talk in Relation to Adolescent Eating Behavior
Authors: Zomerfelde Gita , Pirsko Laura 
Published: January 2023

The aim of the study was to examine whether childhood traumatic experience, trauma symptoms, and family discussions about obesity are associated with adolescent eating behavior. In addition, the study examined gender differences. Participating in the study were 726 adolescents (369 – girls, 344 – boys, 13 – no specific gender) aged 11 to 16. They completed the following questionnaires: Childhood Trauma Questionnaire (Fink et al., 1995); Trauma Symptom Checklist for Children (Briere, 1995); Eating Attitudes Test (Garner et al., 1982); Family Fat Talk Questionnaire (Macdonald et al., 2015). The results showed positive associations between perceived altered eating behaviors and emotional and sexual abuse, depressive and dissociative symptoms, personal and family talk about obesity. Personal conversations about obesity predicted 21% of the variation of the adolescent’s perception of altered eating behavior. The addition of emotional abuse and dissociative symptoms in the regression model increased the explained variance to 25%. Girls reported significantly higher ratings on the study variables.
Etnografia de documentos sobre violações de direitos humanos e trabalho escravo no Rio Negro - AM.
Authors: Menezes Elieyd Sousa de 
Published: January 2023

Desde 2002 várias denúncias sobre trabalho escravo e violações de direitos humanos nos piaçabais do Rio Negro foram realizadas pelas famílias dos trabalhadores extrativistas que estavam imobilizados pela dívida com algum “patrão”. A partir de uma análise documental, bibliográfica e arquivística foi possível a construção de uma etnografia dos documentos sobre essa situação social. O objetivo deste artigo é apresentar a genealogia do processo de judicialização das denúncias sobre trabalho escravo no Rio Negro, atentando para os seguintes questionamentos: Como começou o referido processo de judicialização. Qual o andamento desse processo. Como as denúncias foram recebidas no município e quais os impactos disso nas relações sociais ali estabelecidas. Para responder esses questionamentos foi necessário a leitura e análise do Inquérito Civil 1.13.000.002364/2013-43 levantados no Ministério Público Federal no Amazonas (MPF-AM). A agência dos documentos fez com que o Estado produzisse, por meio do MPF e MPT, ações para garantir os direitos desses trabalhadores extrativistas. A disposição e ordenação desse material documental conta uma história que por séculos foi silenciada, neste caso, a imobilização da força de trabalho de povos indígenas e trabalhadores extrativistas na Amazônia.
Analytical Estimation of the Natural Oscillation Frequency of a Planar Lattice
Authors: Kirsanov M. N. 
Published: January 2023

Introduction. A new scheme of a flat statically determinate regular lattice is proposed. The lattice rods are hinged. The study aims at deriving a formula for the dependence on the number of panels of the first natural oscillation frequency of nodes endowed with masses, each of which has two degrees of freedom in the lattice plane. The rigidity of all rods is assumed to be the same, the supports (movable and fixed hinges) — nondeformable. Another objective of the study is to find the dependence of the stresses in the most compressed and stretched rods on the number of panels in an analytical form. Materials and Methods. An approximate Dunkerley’s method was used to determine the lower bound for the lattice natural frequency. The lattice rigidity was found in analytical form according to Maxwell-Mohr formula. The rod stresses and the reactions of the supports were determined from the equilibrium equations compiled for all lattice nodes. Generalization of the result to an arbitrary number of panels was performed by induction using Maple symbolic math operators for analytical solutions to a number of problems for lattices with different number of panels. Results. The lower analytical estimate of the first oscillation frequency was in good agreement with the numerical solution for the minimum frequency of the oscillation spectrum of the structure. Formulas were found for the stresses in four most compressed and stretched rods and their linear asymptotics. All required transformations were made in the system of Maple symbolic math. Discussion and Conclusions. The obtained dependence of the first frequency of lattice oscillations on the number of panels, mass and dimensions of the structure has a compact form and can be used as a test problem for numerical solutions and optimization of the structure.
Study on Processing Grinding Sludge Conglomerates in Devices with a Rotating Electromagnetic Field
Authors: Lebedev V. A. , Schirin A. A. , Koval N. S. , Vernigorov Yu. M. 
Published: January 2023

Introduction. The key stages of sludge processing technology are the destruction of conglomerates into metal and non-metal components, as well as the grinding of component particles to obtain secondary raw materials of the required granulometric composition. The use of a rotating electromagnetic field for processing grinding sludge makes it possibleto exclude the application of various means of destruction and grinding, avoiding contact interaction of agglomerates and the walls of the working chamber. Thus, the material consumption of technical means is reduced, and the efficiency of the destruction process is increased. The study aimed at establishing the features and basic patterns of sludge waste processing in devices with a rotating electromagnetic field. Materials and Methods. For the research, grinding sludge was used, which was a collection of conglomerates of arbitrary shape, consisting of 80-85 % of metal chips. An induction method was applied based on establishing the connection of the EMF induced in an induction sensor and the magnetic induction of a rotating electromagnetic field. The influence of induction on the nature of interaction between sludge particles in a rotating electromagnetic field was evaluated by changing the relative EMF signal induced in an inductive sensor. Results. As a result of experimental studies conducted using the induction method, it has been found that the dynamic characteristics of sludge waste conglomerates depend on the induction of a rotating field to a certain value. With an increase in the size of sludge conglomerates, with the same size of ferromagnetic particles entering it, the magnitude of the magnetic field induction required for their destruction decreased. With a decrease in the particle size of conglomerates, the field induction required for the destruction of conglomerate bonds increased. An increase in the number of particles in the conglomerate reduced the value of induction. The degree of destruction of the conglomerate and the grinding of its ferromagnetic particles depended on the duration of the rotating electromagnetic field induction. Discussion and Conclusions. The proposed induction method makes it possible to investigate the influence of electromagnetic field parameters on the change in the state of the magnetic vibrating layer, as well as to evaluate the kinematic characteristics of ferromagnetic medium particles in the magnetic vibrating layer.