bluuebunny/crossref_metadata_2025_split huggingface dataset:
Insomnische Symptome und Suizidalität – Zusammenhänge und Management
Authors: Schwerthöffer Dirk , Förstl Hans 
Published: May 2023

Zusammenfassung
Hintergrund
Ein Zusammenhang zwischen insomnischen Symptomen und Suizidalität wurde lange vermutet und ist von besonderem klinischem Interesse.

Ziel
Wir untersuchen aktuelle Hinweise aus Epidemiologie und Neurobiologie auf diesen Zusammenhang, um ein gezieltes Management vorzuschlagen.

Material und Methode
Klinisches Beispiel und selektive Medline-Literaturrecherche zu insomnischen Symptomen und Suizidalität.

Ergebnisse
Epidemiologische Daten weisen auf insomnische Symptome als unabhängigen Risikofaktor für Suizidalität hin. Neurobiologische Befunde unterlegen eine Beziehung zwischen insomnischen Symptomen und Suizidalität, u. a. durch eine serotonerge Dysfunktion sowie eine besonders beeinträchtigte circadiane Rhythmik mit konsekutiver Hypofrontalität, beeinträchtigter Problemlösefähigkeit und verminderter Impulskontrolle. Im Rahmen der Suizidprävention muss bei Patienten mit kombinierten insomnischen und depressiven Symptomen nachdrücklich nach weiteren Risikofaktoren für Suizidalität gesucht werden, u. a. soziale Isolation, nächtliche Grübelneigung, komorbide psychische Erkrankungen, Zugang zu potenziell toxischen Pharmaka oder Waffen.

Schlussfolgerung
Besonders bei Patienten mit weiteren Suizid-Risikofaktoren müssen insomnische Symptome frühzeitig konsequent behandelt werden. In der Pharmakotherapie sind für Patienten mit insomnischen Symptomen und Suizidalität schlaffördernde Antidepressiva mit niedriger Toxizität und Antipsychotika vorzuziehen. Eine an den circadianen Rhythmus angepasste multimodale antiinsomnische und antidepressive Therapie könnte die Zusammenhänge zwischen depressiv-suizidalen und insomnischen Symptomen günstig beeinflussen.
Optimization with artificial intelligence in additive manufacturing: a systematic review
Authors: Ciccone Francesco , Bacciaglia Antonio , Ceruti Alessandro 
Published: May 2023

AbstractIn situations requiring high levels of customization and limited production volumes, additive manufacturing (AM) is a frequently utilized technique with several benefits. To properly configure all the parameters required to produce final goods of the utmost quality, AM calls for qualified designers and experienced operators. This research demonstrates how, in this scenario, artificial intelligence (AI) could significantly enable designers and operators to enhance additive manufacturing. Thus, 48 papers have been selected from the comprehensive collection of research using a systematic literature review to assess the possibilities that AI may bring to AM. This review aims to better understand the current state of AI methodologies that can be applied to optimize AM technologies and the potential future developments and applications of AI algorithms in AM. Through a detailed discussion, it emerges that AI might increase the efficiency of the procedures associated with AM, from simulation optimization to in-process monitoring.
The Role of Advanced Parental Age in Reproductive Genetics
Authors: Chu Boling , Liu Zhi , Liu Yihong , Jiang Hui 
Published: May 2023

AbstractThe increase of parental reproductive age is a worldwide trend in modern society in recent decades. In general, older parents have a significant impact on reproductive genetics and the health of offspring. In particular, advanced parental age contributes to the increase in the risk of adverse neurodevelopmental outcomes in offspring. However, it is currently under debate how and to what extent the health of future generations was affected by the parental age. In this review, we aimed to (i) provide an overview of the effects of age on the fertility and biology of the reproductive organs of the parents, (ii) highlight the candidate biological mechanisms underlying reproductive genetic alterations, and (iii) discuss the relevance of the effect of parental age on offspring between animal experiment and clinical observation. In addition, we think that the impact of environmental factors on cognitive and emotional development of older offspring will be an interesting direction.
Two classes of operators related to the perturbation classes problem
Authors: González Manuel , Salas-Brown Margot 
Published: May 2023

AbstractLet $${{\mathcal {S}}}{{\mathcal {S}}}$$

S
S

and $${{\mathcal {S}}}{{\mathcal {C}}}$$

S
C

be the strictly singular and the strictly cosingular operators acting between Banach spaces, and let $$P\Phi _+$$

P

Φ
+

and $$P\Phi _+$$

P

Φ
+

be the perturbation classes for the upper and the lower semi-Fredholm operators. We study two classes of operators $$\Phi {\mathcal {S}}$$

Φ
S

and $$\Phi {\mathcal {C}}$$

Φ
C

that satisfy $${{\mathcal {S}}}{{\mathcal {S}}}\subset \Phi {\mathcal {S}}\subset P\Phi _+$$

S
S
⊂
Φ
S
⊂
P

Φ
+

and $${{\mathcal {S}}}{{\mathcal {C}}}\subset \Phi {\mathcal {C}}\subset P\Phi _-.$$

S
C
⊂
Φ
C
⊂
P

Φ
-

.

We give some conditions under which these inclusions become equalities, from which we derive some positive solutions to the perturbation classes problem for semi-Fredholm operators.
Methodology of the quantitative assessment of the moisture content of saline brick walls in historic buildings using machine learning
Authors: Hoła Anna 
Published: May 2023

Abstract
Conducting moisture tests of brick walls in buildings under conservation protection is associated with many difficulties that result from the inability to freely interfere with historic tissue. The current paradigm of conducting such research, which assumes the use of just one non-destructive method, has many limitations that affect the accuracy of obtained results. Up-to-date research concerning an alternative non-invasive method, which allows reliable test results to be obtained in the case of the quantitative assessment of the moisture content of saline brick walls in historic buildings, has shown that it is possible to reliably assess such a moisture content using machine learning and two complementary non-destructive methods. In the article, the original methodology of such a quantitative assessment is described and presented in the form of block diagrams. The methodology consists of two stages. The first stage includes carrying out experimental and archival research in selected historical buildings to create a data set. The second stage involves generating a machine learning model for assessing the moisture content based on algorithms and the data collected in the first stage. The article is illustrated with an example of the application of the developed methodology to assess the moisture content of the brick walls of the Golden Gate building in Gdańsk. The presented example shows the reliability and practical usefulness of the developed methodology.
The Effect of Combining the COVID-19 Vaccine with the Seasonal Influenza Vaccine on Reducing COVID-19 Vaccine Rejection Among Libyans
Authors: Ghazy Ramy Mohamed , Sallam Malik , Abdullah Fatimah Saed Alabd , Hussein Mai , Hussein Mohamed Fakhry 
Published: May 2023

AbstractBackgroundCoronavirus disease 2019 (COVID-19) vaccine coverage remains low in Libya compared to other countries in the Eastern Mediterranean Region. This study aimed to evaluate the willingness of the general public in Libya to receive COVID-19 and seasonal influenza vaccines. Additionally, the study aimed to investigate the potential effect of combining the two vaccines to reduce COVID-19 vaccine rejection.MethodsAn anonymous nationwide online cross-sectional survey was carried out from 1st September to 16th October 2022. Libyans aged 18 years or older were recruited using convenience and snowball sampling approaches. The participants were surveyed for sociodemographic information, health status, and vaccination attitude towards COVID-19 and seasonal influenza vaccines.ResultsA total of 2484 participants formed the final study sample: 68.7% were females, 39.4% were aged 18–25 years, 50.4% were single, 32.5% had previous COVID-19 infection, and 47.2% experienced COVID-19 death among relatives. Three-fourths of the respondents showed COVID-19 vaccine rejection: 57.3% did not receive COVID-19 vaccination, 10.1% would not complete the primary vaccination series, and 7.8% refused booster doses. About 55.0% rejected seasonal influenza vaccination, while 1.9% reported influenza vaccine uptake and 21.2% were willing to get the influenza vaccine for the first time. Additionally, 18.8% had already received influenza vaccination in the last year and intended to get the vaccine this season, while 3.3% were unwilling to get influenza vaccination this year despite receiving it in the last influenza season. Age, sex, and occupation were significantly associated with COVID-19 and influenza vaccine rejection. Rejection of COVID-19 vaccination decreased if its combination with influenza vaccine as a single dose was suggested, with 28.2% of the COVID-19 vaccine rejector group accepting the combined vaccine as it would be safer (50.9%), needing fewer injections (24.0%), would be more effective (19.1%), and would be less expensive (3%). Approximately 73.0% of the COVID-19 vaccine rejector group refused this combination due to fear of side effects (48.7%), absence of published studies on this combination (29.8%), and considering this combination as useless (11.2%).ConclusionIn Libya, the prevalence of COVID-19 vaccine rejection was high, while the rejection of seasonal influenza vaccination was relatively lower. If influenza and COVID-19 vaccines are administered simultaneously as a single injection, this may reduce the rejection of the COVID-19 vaccine due to better-perceived vaccine safety and efficacy besides being more convenient in terms of the number of injections and cost.
Hannah Arendt, Baʿthism, and Anfal
Authors: Ahmed Nabaz Samad 
Published: May 2023

AbstractIn the twentieth century, totalitarianism emerged as a new phenomenon, with powerful new regimes sweeping to power on the backs of the ideologies of National Socialism, Bolshevism, and Baʿthism. Armed with these ideologies, and in their names, such regimes committed murder at a mass scale previously unknown to world history. Among the victims of this historical process were the Kurds in Iraq, who were subjected to genocide at the hands of the Baʿthist regime. This article addresses the relationship between totalitarianism and genocide, and specifically how the Baʿthist regime justified genocide against the Kurds. It argues that three elements in Hannah Arendt's theory of totalitarianism –ideology, terror, and total domination – explain why every totalitarian regime in history has wound up resorting to genocidal programs. Using the 1980s Anfal campaign by the Baʿthist regime against the Kurds as a case study, this article elucidates the relationship between totalitarianism and genocide. This analysis will lead to a better understanding of the justifications, features, and motivations of the Baʿthist regime's genocide against Kurds.
ON THE ITERATES OF THE SHIFTED EULER’S FUNCTION
Authors: LEONETTI PAOLO , LUCA FLORIAN 
Published: May 2023

AbstractLet
$\varphi $
be Euler’s function and fix an integer
$k\ge 0$
. We show that for every initial value
$x_1\ge 1$
, the sequence of positive integers
$(x_n)_{n\ge 1}$
defined by
$x_{n+1}=\varphi (x_n)+k$
for all
$n\ge 1$
is eventually periodic. Similarly, for all initial values
$x_1,x_2\ge 1$
, the sequence of positive integers
$(x_n)_{n\ge 1}$
defined by
$x_{n+2}=\varphi (x_{n+1})+\varphi (x_n)+k$
for all
$n\ge 1$
is eventually periodic, provided that k is even.
Luteinizing hormone secretion, ovulatory capacity, and oocyte quality in peripubertal Gir heifers
Authors: Oliveira Clara Slade , Rosa Paola Maria da Silva , Alves Bruna Rios Coelho , Monteiro Clara Ana Santos , Leal Gabriela Ramos , Guedes Pedro Henrique Evangelista , Camargo Agostinho Jorge dos Reis , Saraiva Naiara Zoccal 
Published: May 2023

SummaryInduction of puberty in cattle breeds that attain puberty in later stages, such as Gir, allows the earlier beginning of reproductive life and it might increase oocyte quality. Here, the ovulatory capacity of prepuberal Gir heifers was studied and its relationship to follicular growth, luteinizing hormone (LH) secretion and oocyte quality was evaluated. Peripubertal Gir heifers were treated with a progesterone-based protocol and according to ovulatory response were separated into groups: not-ovulated (N-OV) and ovulated (OV). Serial blood samples were taken 24 h after estradiol treatment on day 12 to evaluate LH secretion. Cumulus–oocyte complexes (COCs) were collected using ovum pick-up and assessed for brilliant cresyl blue (BCB) staining rate, IVF-grade oocytes rate, and mean oocyte diameter, in comparison with cow oocytes. Gene expression of developmental competence markers (ZAR1, MATER, and IGF2R) was also analyzed. The largest follicle diameters were similar between N-OV and OV groups on the day of estradiol treatment (d12) and the next day and decreased (P = 0.04) in the N-OV group thereafter. LH pulse secretion was different between groups (N-OV = 3.61 ± 0.34 vs OV = 2.83 ± 0.21 ng/ ml; P = 0.04). COC assessment showed that the number of recovered oocytes, BCB+ rate, IVF-grade oocytes and oocyte size was similar (P > 0.05) among groups, resembling adult cow patterns. ZAR1, MATER and IGF2R gene expression in oocytes were also similar (P > 0.05) in N-OV and OV groups. In conclusion, our results demonstrate a lower LH secretion profile in peripubertal Gir heifers prone to ovulate after induction protocol, and that oocyte quality is not affected on a short-term basis by ovulation itself.
Fetal echocardiographic features associated with bicuspid aortic valve
Authors: Burns Joseph , Ganigara Madhusudan , Cerise Jane E. , Hayes Denise A. 
Published: May 2023

AbstractBackground:Prenatal diagnosis of bicuspid aortic valve is challenging. Bicuspid aortic valve is often associated with aortic dilation.Methods:Fetuses with postnatally confirmed bicuspid aortic valve were gestational age-matched with normal controls. Complex lesions were excluded. Aortic valve and arch measurements by two blinded investigators were compared.Results:We identified 27 cases and 27 controls. Estimated fetal weight percentile was lower in cases than controls. Seven cases had one or more significant lesions including perimembranous ventricular septal defects (n = 2), isolated annular hypoplasia (n = 2), and/or arch hypoplasia/coarctation (n = 4). Fetuses with bicuspid aortic valves had significantly smaller median z-scores of the aortic annulus (–1.60 versus –0.53, p < 0.001) and root (–1.10 versus –0.53, p = 0.040), and larger ratios of root to annulus (1.32 versus 1.21, p < 0.001), sinotubular junction to annulus (1.07 versus 0.99, p < 0.001), ascending aorta to annulus (1.29 versus 1.18, p < 0.001), and transverse aorta to annulus (1.04 versus 0.96, p = 0.023). Leaflets were “doming” in 11 cases (41%) and 0 controls (p = 0.010), “thickened” in 10 cases (37%) and 0 controls (p = 0.002). We noted similar findings in the subgroup without significant additional cardiac defects.Conclusions:The appearance of doming or thickened aortic valve leaflets on fetal echocardiogram is associated with bicuspid aortic valve. Compared to controls, fetuses with bicuspid aortic valve had smaller aortic annulus sizes (possibly related to smaller fetal size) without proportionally smaller aortic measurements, resulting in larger aortic dimension to annulus ratios. Despite inherent challenges of diagnosing bicuspid aortic valve prenatally, these findings may increase suspicion and prompt appropriate postnatal follow-up.
Role of Twins in Waardenburg Syndrome: 1916 − present/Twin Research Reviews: MZ Twins’ Different Dermatoglyphics; Twins with Sagittal Suture Crainosynostosis; Blood Pressure in Female Twins; MZ Twins’ Education and Political Knowledge/Media Reports: Twins Created by Reciprocal In Vitro Fertilization; Reared-Apart Triplets’ Limited TV Series; Abducted Twin Infants; Winkelvoss Twins Charged by the Securities and Exchange Commission; Going From ‘Me’ to ‘We’
Authors: Segal Nancy L. 
Published: May 2023

AbstractWaardenburg’s syndrome involves deafness accompanied by various visual difficulties. The role of twins in identifying this disorder and advancing understanding of its origins and symptoms is described, beginning in 1916 and continuing to the present. This overview is followed by current research on monozygotic (MZ) twins’ different dermatoglyphic features, twins with sagittal suture crainosynostosis, blood pressure in female twins, and MZ twins’ education and political knowledge. The final section presents media reports describing controversies surrounding twins created by reciprocal in vitro fertilization, reared-apart triplets’ limited TV series, abducted twin infants, the Winkelvoss twins’ charges by the Securities and Exchange Commission, and going from ‘Me’ to ‘We’.
Early postoperative outcome after carotid artery endarterectomy with	bifurcation advancement
Authors: Moehle Felix L. , Krueger Bernard , Menges Anna-Leonie , Rancic Zoran , Zimmermann Alexander 
Published: May 2023

Summary: Background: The aim of this study is to review the single center experience in surgical treatment of carotid artery disease (CAD) using bifurcation advancement carotid endarterectomy (BA-CEA) and compare the in-hospital outcome with one of the largest nationwide carotid endarterectomy (CEA) databases worldwide, the German statutory quality assurance database (GD). Patients and methods: Data of BA-CEA procedures in the period of 2006–2015 were analyzed retrospectively. The primary endpoint was defined as combined stroke and death rate. Secondarily, isolated stroke, TIA, patient death, myocardial infarction, major neck hematoma and cranial nerve injuries were analyzed. Symptomatic and asymptomatic CAD patients were divided into two subgroups. The results were compared to extracted published data from the German database (GD). Results: Of 239 included BA-CEA procedures 188 (78.7%) procedures were carried out in patients with symptomatic carotid artery stenosis. The overall perioperative combined stroke and death rate after BA-CEA was 2.5%. Five (2.1%) patients suffered from a stroke (one minor and four major strokes), of which two hemorrhagic strokes ended fatally. Overall, four (1.7%) patients died perioperatively. The combined stroke and death rate was higher in the symptomatic subgroup (3.2%; 0% in the asymptomatic group). No significant differences were found between the results of BA-CEA and the German database (n=142’074) for combined stroke and death rates and isolated stroke. Significant differences were found among the overall mortality rate (BA-CEA: 1.7% vs. GD: 0.6, p=0.04). The risk of postoperative cranial nerve injuries was also significantly higher after BA-CEA overall (BA-CEA: 5.0% vs. GD: 1.2%, p=<0.0001), in symptomatic CAD patients (BA-CEA: 4.8% vs. GD: 1.2%, p=<0.0001) and in asymptomatic CAD patients (BA-CEA: 5.9% vs. GD: 1.3%, p=0.01). Conclusions: CEA with bifurcation advancement provides comparable perioperative results, focusing on combined stroke and mortality, but seems to have some technical drawbacks, which may lead to more frequent local neurological complications.
Equitable Data Governance Models for the Participatory Sciences
Authors: Cooper Caren , Martin Vincent , Wilson Omega , Rasmussen Lisa 
Published: May 2023

AbstractWhen participants share data to a central entity, those who have taken on the responsibility of accepting the data and handling its management may also have control of decisions about the data, including its use, re‐use, accessibility, and more. Such concentrated control of data is often a default practice across many forms of participatory sciences, which can be extractive in some contexts and a way to protect participants in other contexts. To avoid extractive practices and related harms, projects can adopt structures so that those who make decisions about the data set and/or each datum are different from those responsible for executing the subsequent decisions about data management. We propose two alternative models for improving equity in data governance, each model representing a spectrum of options. With an individualized control model, each participant can place their data in a central repository while still retaining control of it, such as through simple opt‐in or opt‐out features or through blockchain technology. With a shared control model, representatives of salient participant groups, such as through participant advisory boards, collectively make decisions on behalf of their constituents. These equitable models are relevant to all participatory science systems, and particularly necessary in contexts where dominant‐culture institutions engage marginalized peoples.
The Role of Tropical Cyclone on Changjiang River Subaqueous Delta Geomorphology: A Numerical Investigation of Tropical Cyclone Danas (2019)
Authors: Tang Bixuan , Zhang Fan , Jia Jianjun , Feng Zhixuan , Tang Jieping , Xing Fei , Wang Ya Ping 
Published: May 2023

AbstractSubaqueous deltas are facing growing threats of erosion. Tropical cyclones (TCs), which are predicted to affect mid‐latitude estuaries more frequently with higher intensity in the future, can play an important role in subaqueous delta geomorphology change. Nevertheless, direct in situ measurement of TC‐induced bed elevation change (BEC) was rarely reported before. In this study, four tripods were deployed at different parts of the Changjiang River subaqueous delta (CRSD) to capture BEC during TCs in July 2019. Rapid erosion (20 mm day−1) during TC Danas (2019) was observed by high precision bed elevation measurement, over 10 times faster than that during calm weather conditions. Moreover, the recorded rates of BEC varied substantially among these stations. A coupled three‐dimensional wave‐current‐sediment model was then developed for the CRSD to help understand the spatial variability of observed BEC. The model results showed two striking features of BEC during TC Danas: (a) enhanced sediment accretion near the sharp bottom salinity front offshore of the north channel; (b) marked erosion near the front of CRSD. Further analysis showed that the converging bottom currents in concert with enhanced sediment resuspension during TC Danas led to significant convergence of sediment flux near the bottom salinity front. In addition, the diverging isobaths along the front of the CRSD resulted in the onshore deviation of bottom current and diverging sediment flux under the downwelling‐favorable winds of Danas. Many TCs in the CRSD generate similar downwelling‐favorable winds and currents, growing TC threats in the future may therefore exacerbate erosion in this region.