bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rita Cloth Store: rethinking for the times
Authors: Kundu Soumyadeep , Mateen Arqum 
Published: September 2023

Social implications
Cases currently available on business model canvas pertain to large multi-national companies. However, this case takes the happenings at a relatively small business and applies the business model canvas there. Through the case, the authors illustrate how small Indian businesses in various small towns and cities are adapting to the disruptions in their businesses. In addition, insight regarding omnichannel operations and their implementation and decision-making at the level of such small businesses is also provided.

Learning outcomes
The case intends to acquaint participants with the business model canvas and its application in evaluating business models, identifying shortcomings and adapting business models accordingly. The case also provides an overview of how small businesses across India are adapting to the disruptions brought about by their traditional business models. The case also provides insights into omnichannel operations and the challenges of implementation.

Case overview/synopsis
Small family-owned establishments/businesses today are faced with an onslaught of disruptions to their prevalent ways of doing business. This case deals with one such business, Rita Cloth Store. The case follows in the footsteps of Sampa Kar, who realises the need for re-evaluating their decades-old business and rethinks their business model to adapt to the changing times and consumer habits. She must consider a number of measures to transform Rita Cloth Store as she attempts to change the decades-old business models to ensure its survival.

Complexity academic level
The case can be taught in undergraduate and post-graduate courses on entrepreneurship, business models and operations strategy.

Supplementary materials
Teaching Notes are available for educators only.

Subject code
CCS 3: Entrepreneurship
Using the Fantastic Reality Ability Measurement to cope with epidemics: a Turkish validity and reliability study
Authors: Özyer Güvener Yasemin , Dinçer Samet , Caner Enver 
Published: September 2023

PurposeThis study was conducted to adapt the Fantastic Reality Ability Measurement (FRAME) into Turkish.Design/methodology/approachIn the sample of this methodological study, 213 participants were included.FindingsThe factor loading of the tool was within the appropriate range (0.53–0.94). Its Cronbach's alpha was 0.975, and the item total score correlations ranged between 0.594 and 0.881.Originality/valueThe evaluation of the Turkish version of the FRAME revealed that it could be used as a valid and reliable measurement tool in Turkish population.
The relationship between AI stimuli and customer stickiness, and the roles of social presence and customer traits
Authors: Li Gang , Zhao Zhihuang , Li Lan , Li Yuanbo , Zhu Mengjiao , Jiao Yongxin 
Published: September 2023

PurposeThis study investigates the influence of artificial intelligence (AI) stimuli on customer stickiness (CS), the mediation effects of social presence (SP) and the moderating impacts of customer traits in this influencing process.Design/methodology/approachDrawing on the arousal theory and social response theory, a conceptual model was established and tested by a data set of 268 customers in the catering industry.FindingsThe results indicate that AI stimuli, such as perceived personalization and perceived interactivity, positively affect CS. SP partially mediates the influence of AI stimuli on CS. Customer traits such as customers' need for interaction (NFI) and novelty seeking (NS) actively moderate the mediating effects of SP.Originality/valueThis study advances the interactive marketing literature from three aspects. Firstly, instead of focusing on the functional aspects of AI stimuli, it extends our understanding of AI-enabled interactive marketing by examining the effects of social and emotional aspects of AI stimuli on customer response. Secondly, it extends our understanding of social response by illuminating the mediating effects of SP between AI stimuli and CS. Finally, it provides new insights and empirical evidence for the research focus on customer traits in AI-enabled interactive marketing.
Optimal contracting with asymmetric risk aversion information and fairness concerns
Authors: Chang Jiajia , Hu Zhi Jun , Zhao Hui 
Published: September 2023

PurposeThis study considers a contracting problem between a fairness concerned entrepreneur (EN) and a fair-neutral venture capitalist (VC) to explore the effects of asymmetry, agency conflicts and fairness concerns.Design/methodology/approachThe authors construct the model by assuming the EN's risk aversion degree is private information, which is more realistic but ignored in most studies. Under the principal–agent framework, the authors solve the VC's optimal contracting models by identifying the ranges of feasible solution, where the optimal solutions of these models are explicit and nicely reconcile the “private equity” puzzle. Moreover, validity of the optimal solutions is verified by numerical simulations.FindingsIn accordance with empirical evidence, information asymmetry lowers the optimal equity share that the VC provides to EN but raises EN's profit due to lower effort disutility and information rent. Moreover, the authors find that the fairness concerns is beneficial for the EN, where it not only increases the EN's optimal equity share, but also enhances the certainty equivalence of the EN's utility regarding its profit. Relative to the benchmark model where the EN's risk aversion degree is common knowledge, the EN's efforts recommended by the optimal contract is less sensitive to the EN's fairness concerns degree when the EN does not actually announce its risk aversion degree.Originality/valueFirst, the authors incorporate asymmetry to study a two-period contracting problem and explore how it affects the equity shares allocated to the contractual parties. Second, the authors incorporate fairness concerns and analyze its effect regarding the decision-makings and profits.
Examining measurement invariance of an ICT literacy self-efficacy scale across gender: a comparative study
Authors: Al-Nuaimi Maryam Nasser 
Published: September 2023

PurposeDespite the ever-increasing importance of cultivating information, communication and technology literacy skills among college students, they have yet to be related to comprehensive measuring instruments. A glance at the empirical literature reveals that most pertinent scales have been confined to measuring Internet literacy skills, whereas educators in the 21st century advocate an inclusive conceptualization of ICT literacy. Such a comprehensive conceptualization embodies technical, critical, cognitive and emotional competencies. Additionally, more empirical evidence is needed to indicate gaps in testing measurement invariance of ICT literacy scales across genders or cultures. To that end, the current study aims to adapt and cross-validate an ICT literacy self-efficacy scale across gender by testing the measurement invariance using a multiple-sampling confirmatory factor analysis (MCFA). Furthermore, the current study aims to verify the ICT literacy self-efficacy scale's psychometric properties to establish its construct validity and understand the scale's underlying factorial structure.Design/methodology/approachThe current study has administered the scale to a cross-sectional sample of 3560 undergraduate students enrolled in six universities in the Sultanate of Oman.FindingsThe results have revealed that the ICT literacy self-efficacy exhibits satisfactory indices of construct validity. On the other hand, the results of MCFA demonstrate that the differences in the goodness of fit indices between the nested models and the baseline model were below the cut-off criterion of 0.01, indicating invariance. Therefore, the scale has proved to be amenable for comparing genders on their ICT literacy self-efficacy using an one-way multivariate analysis of variance.Originality/valueThe study has several implications for research and pedagogical practices. The study provides empirical evidence for establishing ICT literacy self-efficacy as a distinct high-domain construct of task-specific self-efficacy beliefs.
Quality education through writing: aligning learning objectives in learning materials and question papers using Bloom’s taxonomy
Authors: Chavda Mrunal , Patel Harsh , Bhatt Hetav 
Published: September 2023

Purpose
This study aims to examine the effectiveness of the Central Board of Secondary Education (CBSE)-based English textbooks and question papers in developing second-language higher-order thinking skills (HOTS).

Design/methodology/approach
Descriptive analysis establishes a causal relationship between learning objectives and second language (L2) writing proficiency. Content analysis is used to compare and analyze tabulated data for textbooks and question papers for the English language by the National Council of Educational Research and Training (NCERT) and CBSE. This method categorizes the materials and their assessments under HOTS and lower-order thinking skills to ascertain the relationship between learning objectives and L2 writing proficiency.

Findings
The study highlights teaching material and assessment shortcomings and their alignment with learning outcomes to enhance students' writing skills. It underscores the need for HOTS-focused materials, discussing their impact on writing skills. The study also explores how textbook–question paper mismatch hampers Bloom's taxonomy-based cognitive skills.

Practical implications
This research illuminates the efficacy of teaching and learning English as a second language (ESL) writing skills to improve the quality of education, which has real-world implications. The study highlights flaws in the educational system in India and suggests curricular and pedagogical changes.

Originality/value
The research examines NCERT and CBSE ESL textbooks and question papers to align teaching and assessment methods. The results aim to improve education through ESL writers' HOTS.
The internationalisation of doctoral education and the strategies to achieve it: the perspectives of Portuguese universities and doctoral students
Authors: Cardoso Sónia , Sin Cristina 
Published: September 2023

Purpose
Internationalisation is one of the significant manifestations of the ongoing transformation of doctoral education. The purpose of this paper is to focus on the perspectives of Portuguese universities and doctoral students regarding the importance of internationalisation and the strategies to achieve it in doctoral education.

Design/methodology/approach
A sample of 118 doctoral programme websites from 27 universities (15 public, 12 private) served as the data source of university perspectives of internationalisation. Doctoral students’ perspectives on the same topic were collected through 31 interviews, 27 conducted in seven focus groups and four individually, with first-year doctoral students from three Portuguese public universities. Content analysis was performed on the two sets of data.

Findings
According to university and doctoral students’ perspectives, internationalisation assumes an important role in Portuguese doctoral education and is being integrated through specific strategies. Strategies for attracting and recruiting international students appear to take a back seat compared to strategies which offer students international experience through immersion in international environments in their home institutions. While expressing the potential impediments, undesirable side effects and conditions that internationalisation must meet, students seem to take a critical stance towards it and towards the institutional strategies designed to promote it.

Originality/value
This paper addresses a topic which does not appear to receive much attention in doctoral education research and, to this extent, advances knowledge on the internationalisation of doctoral education.
Effects of word emotional experience and participant emotionality in lexical decision
Authors: Prueitt Ethan , Yates Mark 
Published: September 2023

BackgroundPrevious research has shown that the emotional content of words affects how quickly they are recognised. One recent measure of word emotionality is emotional experience that measures the degree to which reading a word can invoke emotional experiences tied to the word. Words that are higher in emotional experience are recognised more rapidly in the lexical decision task.MethodsThe current study examines how words' emotional experience and participants' emotionality affect performance on the lexical decision task. To this end, participants were given five emotion measures and completed a lexical decision task with words varying on emotional experience.ResultsIt was found that participants who scored higher on the Positive and Negative Affect Schedule showed a weaker emotional experience effect. No other emotion measures interacted with emotional experience.ConclusionsThese results are predicted by and interpreted within a framework where the semantic representation of words includes emotion information that is grounded in experience of our internal states.
Cell‐type specific impact of metformin on monocyte epigenetic age reversal in virally suppressed older people living with HIV
Authors: Corley Michael J. , Pang Alina P. S. , Shikuma Cecilia M. , Ndhlovu Lishomwa C. 
Published: September 2023

AbstractThe anti‐diabetic drug metformin may promote healthy aging. However, few clinical trials of metformin assessing biomarkers of aging have been completed. In this communication, we retrospectively examined the effect of metformin on epigenetic age using principal component (PC)‐based epigenetic clocks, mitotic clocks, and pace of aging in peripheral monocytes and CD8+ T cells from participants in two clinical trials of virologically‐suppressed people living with HIV (PLWH) with normal glucose receiving metformin. In a small 24‐week clinical trial that randomized participants to receive either adjunctive metformin or observation, we observed significantly decreased PCPhenoAge and PCGrimAge estimates of monocytes from only participants in the metformin arm by a mean decrease of 3.53 and 1.84 years from baseline to Week 24. In contrast, we observed no significant differences in all PC clocks for participants in the observation arm over 24 weeks. Notably, our analysis of epigenetic mitotic clocks revealed significant increases for monocytes in the metformin arm when comparing baseline to Week 24, suggesting an impact of metformin on myeloid cell kinetics. Analysis of a single‐arm clinical trial of adjunctive metformin in eight PLWH revealed no significant differences across all epigenetic clocks assessed in CD8+ T cells at 4‐ and 8‐week time points. Our results suggest cell‐type‐specific myeloid effects of metformin captured by PC‐based epigenetic clock biomarkers. Larger clinical studies of metformin are needed to validate these observations and this report highlights the need for further inclusion of PLWH in geroscience trials evaluating the effect of metformin on increasing healthspan and lifespan.
Use of antipsychotics and antidepressants in first‐episode psychotic depression: A nationwide register‐based study
Authors: Hamina A. , Paljärvi T. , Tanskanen A. , Lähteenvuo M. , Tiihonen J. , Taipale H. 
Published: September 2023

AbstractBackgroundAccording to guidelines, psychotic depression should be treated with both antipsychotics and antidepressants, but current practice is largely unknown. We investigated the prevalence of antipsychotic and antidepressant use in first‐episode psychotic depression and factors related to antipsychotic use after the diagnosis.MethodsWe identified individuals aged 16–65 with a first‐episode diagnosis of psychotic depression (ICD‐10 codes F32.3, F33.3) from nationwide data linkage of Finnish healthcare and population registers during 2000–2018. Point prevalence was measured as 2‐week time windows every 3 months, investigating whether the individual had a modeled drug use period ongoing during the window or not, censoring to death and end of data linkage.ResultsThe study population included 18,490 individuals (58.0% women; mean age 39.9 years, standard deviation 14.7). The prevalence of use for antidepressants (75.0%), antipsychotics (56.4%), and both (50.0%) were highest at 3 months after the diagnosis. The prevalence declined to 51.8%, 34.1%, and 28.7%, respectively, at 3 years after the diagnosis. In a logistic regression analysis, younger age (adjusted odds ratio < 25 vs. ≥55, 0.82 [95% confidence interval 0.73–0.91]), eating disorders (0.78 [0.66–0.92]), substance use disorders (0.80 [0.73–0.87]), and occupational inactivity (0.80 [0.73–0.87]) were associated with decreased odds of using antipsychotics at 3 months after diagnosis. Increased odds were found for diagnosis from inpatient care (1.74 [1.62–1.86]), and later year of cohort entry (2010–2014 vs. 2000–2004, 1.56 [1.42–1.70]).ConclusionAt most, half of the individuals with newly diagnosed psychotic depression used both antidepressants and antipsychotics. This likely has a negative impact on treatment success.
Eugenol delays the onset of ouabain‐induced ventricular cardiac arrhythmias in guinea pigs
Authors: Teixeira‐Fonseca Jorge Lucas , Santos‐Miranda Artur , Marques Ivan lobo Sousa , Marques Leisiane Pereira , Alcantara Fabiana , de Lima Conceição Michael Ramon , Souza Diego Santos , Santana Gondim Antonio Nei , Roman‐Campos Danilo 
Published: September 2023

AbstractEugenol is an aromatic compound used in the manufacture of medicines, perfumes, cosmetics and as an anaesthetic due to the ability of the drug to block the neuronal isoform of voltage‐gated Na+ channels (NaV). Some arrhythmias are associated with gain of function in the sodium current (INa) found in cardiomyocytes, and antiarrhythmic sodium channel blockers are commonly used in the clinical practice. This study sought to elucidate the potential mechanisms of eugenol's protection in the arrhythmic model of ouabain‐induced arrhythmias in guinea pig heart. Ex vivo arrhythmias were induced using 50 μM of ouabain. The antiarrhythmic properties of eugenol were evaluated in the ex vivo heart preparation and isolated ventricular cardiomyocytes. The compound's effects on cardiac sodium current and action potential using the patch‐clamp technique were evaluated. In all, eugenol decreased the ex vivo cardiac arrhythmias induced by ouabain. Furthermore, eugenol showed concentration dependent effect upon peak INa, left‐shifted the stationary inactivation curve and delayed the recovery from inactivation of the INa. All these aspects are considered to be antiarrhythmic. Our findings demonstrate that eugenol has antiarrhythmic activity, which may be partially explained by the ability of eugenol to change de biophysical properties of INa of cardiomyocytes.
T cell receptor gene‐modified allogeneic T cells with siRNA for endogenous T cell receptor induce efficient tumor regression without graft‐versus‐host disease
Authors: Okada Satomi , Muraoka Daisuke , Yasui Kiyoshi , Tawara Isao , Kawamura Ayumi , Okamoto Sachiko , Mineno Junichi , Seo Naohiro , Shiku Hiroshi , Eguchi Susumu , Ikeda Hiroaki 
Published: September 2023

AbstractAdoptive immunotherapy using genetically engineered patient‐derived lymphocytes to express tumor‐reactive receptors is a promising treatment for malignancy. However, utilization of autologous T cells in this therapy limits the quality of gene‐engineered T cells, thereby inhibiting the timely infusion of the cells into patients. In this study, we evaluated the anti‐tumor efficacy and the potential to induce graft‐versus‐host disease (GVHD) in T cell receptor (TCR) gene‐engineered allogeneic T cells that downregulate the endogenous TCR and HLA class I molecules with the aim of developing an “off‐the‐shelf” cell product with expanded application of genetically engineered T cells. We transduced human lymphocytes with a high‐affinity TCR specific to the cancer/testis antigen NY‐ESO‐1 using a novel retrovirus vector with siRNAs specific to the endogenous TCR (siTCR vector). These T cells showed reduced expression of endogenous TCR and minimized reactivity to allogeneic cells in vitro. In non‐obese diabetic/SCID/γcnull mice, TCR gene‐transduced T cells induced tumor regression without development of GVHD. A lentivirus‐based CRISPR/Cas9 system targeting β‐2 microglobulin in TCR gene‐modified T cells silenced the HLA class I expression and prevented allogeneic CD8+ T cell stimulation without disrupting their anti‐tumor capacity. This report is the first demonstration that siTCR technology is effective in preventing GVHD. Adoptive cell therapy with allogeneic T cells engineered with siTCR vector may be useful in developing an “off‐the‐shelf” therapy for patients with malignancy.
Nuestra ciencia as transborder ecological knowledge and survival
Authors: Azúa Anneleise 
Published: September 2023

AbstractThis article frames what one of my collaborators calls nuestra ciencia (our science) as a concept that expresses a transborder worldview based on region‐specific scientific land and healing practices. I trace the ways Indigenous science came into fierce conflict with the twentieth‐century wave of Anglo settler‐colonial land grabs in south Texas and how the resulting force of mass agriculture enabled mass destruction and biodiversity loss in the region. It offers an environmental, archival, and ethnographic analysis of curanderismo (Mexican traditional medicine) as science and explores its relationship to settler colonialism, environmental degradation, and processes of racialization in relation to health, science, and medical technologies, as well as tracing the ongoing material record of its practice. I frame Mexican transborder healing traditions (curanderismo and plant medicine) as serious social, scientific, and ecological processes. I make it clear that although this practice is often considered a Mexican tradition, de‐Indigenized mestizos also practice, exploit, and appropriate it, while its roots lie in Indigenous lifeways and knowledge.
On the decay of fracture toughness of sandstone subjected to freeze–thaw cycles
Authors: Wei Mengxi , Qiao Lan , Li Qingwen , Deng Naifu 
Published: September 2023

AbstractIn cold regions, progressive cracking, caused by freeze–thaw cycles, plays an important role in deteriorating engineering rock mass. Employing central cracked Brazilian disks (CCBDs) of sandstone, this paper aims at investigating the variations of falling rate among different modes of fracture toughness exposed to freeze–thaw cycles and the applicability of fracture criterion in predictions. Results revealed that different modes of fracture toughness exhibited comparable descending trends after varied freeze–thaw cycles. There was an agreement between the predictions via the generalized maximum tangential stress criterion (GMTS) and the test results. In specified conditions, the GMTS criterion incorporating fracture process zone of 0 freeze–thaw cycle can be applied to estimations for different freeze–thaw cycles. With increasing freeze–thaw cycles the fractal dimensions of mode I and mixed‐mode I–II fracture surfaces displayed a growing trend, indicating that the fracture surfaces became rougher and more complicated.