bluuebunny/crossref_metadata_2025_split huggingface dataset:
Successful treatment of postinfectious bronchiolitis obliterans with gamma globulin in a tertiary center: 10 years of experience
Authors: Yilmaz Aslı İmran , Gül Yahya , Kapaklı Hasan , Ünal Gökçen , Çağlar Hanife Tuğçe , Ercan Fatih , Reisli İsmail , Keleş Sevgi , Poyraz Necdet , Pekcan Sevgi 
Published: July 2023

AbstractIntroductionBronchiolitis obliterans is characterized by partial or total occlusion of the bronchioles due to inflammation and fibrosis, and the most common form is postinfectious bronchiolitis obliterans (PIBO). This study aimed to retrospectively present our intravenous immunoglobulin (IVIG) treatment experience in PIBO patients with a clinically severe course despite receiving commonly used treatment protocols.Materials and MethodsThe study included patients aged 0–18 with subtle immunological abnormalities who were followed up in our center for PIBO between 2010 and 2021. Clinical evaluation, body mass index (BMI), computerized tomography (CT) image scoring, and immunological parameters were recorded before and after IVIG treatment.ResultsOf the 11 patients included in the study, 90% were male, the mean age at diagnosis was 27.1 months (range: 5–68 months) and the mean current age was 81.4 months (range: 15–188 months). The number of hospital visits due to infection and the frequency of hospitalizations decreased markedly in the patients who underwent IVIG therapy. Oxygen therapy was discontinued in all patients, and improvements in radiological severity scores were observed. BMI z‐scores improved over the baseline values after IVIG therapy.ConclusionCorticosteroids are considered the best first‐line treatment to control inflammation in PIBO. In our study group, PIBO patients showed favorable clinical and radiological responses to regular IVIG treatment, possibly due to minor immune deficiency secondary to steroids or as a result of undetected adaptive and innate immune defects involved in the etiology of severe PIBO.
Salivary microbiome and asthma risk in children with orofacial defects
Authors: Chen I‐Lun , Huang Faye , Li Sung‐Chou , Huang Hsin‐Chun 
Published: July 2023

AbstractBackgroundPatients with congenital orofacial defects, cleft lip (CL), cleft palate (CP), and cleft lip and palate (CLP) have continuous exposure of the respiratory system to the microbiome from the oral environment, offering opportunities to develop mucosal immunity in the airway. This two‐part study aims to analyze data on asthma occurrence in CL, CP, and CLP infants and the composition of the salivary microbiome, and to evaluate the oral microbiota and its association with the risk of developing childhood asthma.MethodsPatient data from the research database of Chang Gung Memorial Hospital from 2004 to 2015 were retrospectively analyzed by multivariable regression. Diseases diagnoses were defined by ICD codes. Asthma must also meet the criteria for receiving selective β2 agonistic or/and inhaled corticosteroid treatments twice within 1 year. Analysis of the saliva microbiome was performed prospectively from 2016 to 2020 in 10 healthy term infants and 10 CLP infants on postnatal 7th day, 1 month, and 6 months by next‐generation sequencing.ResultsAsthma and nonasthma groups included 988 and 3952 patients, respectively. The incidence of asthma development was higher in patients with CP than in CL and CLP groups (aOR: 5.644, CI: 1.423–22.376). The species composition of the microbiome at 1 and 6 months was significantly different between infants with CLP and healthy infants.ConclusionChildren with orofacial defects have a higher risk of developing asthma with a possible contribution from oral microbiota in the early months of life.
Effects of wheat varieties, fungicides and application time onFusariumhead blight and deoxynivalenol contamination control in wheat
Authors: Meng DanDan , Dong Xu , He XianFang , Pan Rui , Sun MingNa , Chu Yue , Tong Zhou , Yi XiaoTong , Fan Hui , Gao TongChun , Duan JinSheng 
Published: July 2023

AbstractBACKGROUNDYield loss and toxin contamination caused by wheatFusariumhead blight (FHB) have always been a worldwide concern. Cultivating disease‐resistant varieties and fungicide application are effective measures to control FHB. The comprehensive control technology system for FHB and toxin contamination of wheat in Anhui Province needs further improvement. This study compared the control efficacy of different wheat varieties, fungicides and application times on wheat FHB and deoxynivalenol (DON) contamination, and the dynamic change of DON accumulation after application.RESULTSAmong the 93 main wheat varieties in Anhui Province, the disease‐resistant and low‐toxic wheat variety “Ningmai 26” was more suitable for planting in the central part of Anhui Province. At the same time, “Yangmai 22” was used for subsequent experiments. The field efficacy trials of different fungicides showed that 30% prothioconazole oil dispersion (OD) had the highest control efficacy on FHB and DON contamination, reaching 94.33 and 77.49%, respectively. The study on the optimum application time of prothioconazole showed that the 0–20% flowering stage was the key point of DON control. The survey of the dynamic changes of DON accumulation showed that prothioconazole could significantly reduce the level of DON accumulation while inhibiting the accumulation rate of DON. At the same time, the control fungicide carbendazim increased the level of DON contamination.CONCLUSIONThis study will provide excellent germplasm resources for cultivating disease‐resistant and low‐toxic wheat varieties, and provide a theoretical reference for establishing a collaborative prevention and control system of disease control and toxin reduction. © 2023 Society of Chemical Industry.
Analog Photonics Computing for Information Processing, Inference, and Optimization
Authors: Stroev Nikita , Berloff Natalia G. 
Published: July 2023

AbstractThis review presents an overview of the current state‐of‐the‐art in photonics computing, which leverages photons, photons coupled with matter, and optics‐related technologies for effective and efficient computational purposes. It covers the history and development of photonics computing and modern analogue computing platforms and architectures, focusing on optimization tasks and neural network implementations. The authors examine special‐purpose optimizers, mathematical descriptions of photonics optimizers, and their various interconnections. Disparate applications are discussed, including direct encoding, logistics, finance, phase retrieval, machine learning, neural networks, probabilistic graphical models, and image processing, among many others. The main directions of technological advancement and associated challenges in photonics computing are explored, along with an assessment of its efficiency. Finally, the paper discusses prospects and the field of optical quantum computing, providing insights into the potential applications of this technology.
Prediction of Protein‐Ligand Binding Affinity by a Hybrid Quantum‐Classical Deep Learning Algorithm
Authors: Dong Lina , Li Yulin , Liu Dandan , Ji Ye , Hu Bo , Shi Shuai , Zhang Fangyan , Hu Junjie , Qian Kun , Jin Xianmin , Wang Binju 
Published: July 2023

AbstractRapid and accurate prediction of protein‐ligand binding affinity plays a vital role in high‐throughput drug screening. With the development of deep learning, increasingly accurate prediction models have been established. Deep learning may have ushered in an era of quantization, but the practical use of this theory for protein‐ligand binding affinity is still infrequent. Here, the introduction of the quantum algorithm into classical deep learning is described, which enables it to reliably predict protein‐ligand binding affinity using simple sequence information. Based on different deep learning models, including graph neural networks (GNN) and convolutional neural networks (CNN), corresponding quantum hybrid deep learning models have been constructed and compared to the classical models. This study has shown that the quantum algorithm can achieve considerable accuracy and good generalization, and show potential to balance between accuracy and generalization, although the parameters used in the model have been remarkably reduced. These models based on quantum hybrid deep learning (QDL) show robust predictions on four benchmark datasets, and exhibit the practical application power in drug screening for targets related to human liver cirrhosis. This work highlights the potential of the hybrid quantum deep learning algorithm in solving complex problems in bioinformatics.
Postdeposition Halide Exchange for Achieving Deep‐Blue Perovskite Light‐Emitting Diodes: The Role of the Organic Cations in the Chloride Source
Authors: Zhao Shenghe , Yu Hui , Jia Yongheng , Zhou Yang , Zhang Zheng , Zhao Ni 
Published: July 2023

AbstractPostdeposition halide exchange has been a popular strategy for tuning the emission wavelength of metal halide perovskites and is particularly attractive in achieving deep‐blue perovskite light‐emitting diodes (PeLEDs), where the quality of the emissive layer is largely limited by the low solubility of chlorides in perovskite precursor solution. In this work, the halide exchange strategy is examined for deep‐blue PeLEDs, with a focus on understanding the role of the organic cations of the halide salt (i.e., the chloride source for ion exchange) in modifying the properties of the perovskite films and consequently the PeLED performances. By comparatively investigating the treatment effects of two model systems, namely phenethylammonium chloride and 2,2‐diphenylethylammonium chloride (DPEACl), it is found that although the two chlorides produce highly similar photoluminescence properties of the perovskite films, they create different landscapes for current flow in the PeLEDs. In particular, the bulky branch‐structured DPEA cations exhibit minimal disturbance to the perovskite grains while providing highly effective inter‐grain void filling and thus leakage current blocking, leading to 3D perovskite‐based PeLEDs with a record high peak external quantum efficiency of 6.4% at 462 nm. The study highlights the importance of organic cation selection in the halide exchange processes for PeLEDs.
Reviewing and analyzing shrinkage of peat and other organic soils in relation to selected soil properties
Authors: Seidel Ronny , Dettmann Ullrich , Tiemeyer Bärbel 
Published: July 2023

AbstractPeat and other organic soils (e.g., organo‐mineral soils) show distinctive volume changes through desiccation and wetting. Important processes behind volume changes are shrinkage and swelling. There is a long history of studies on shrinkage which were conducted under different schemes for soil descriptions, nomenclatures and parameters, measurement approaches, and terminologies. To date, these studies have not been harmonized in order to compare or predict shrinkage from different soil properties, for example, bulk density or substrate composition. This, however, is necessary to prevent biases in the determination of volume‐based soil properties or for the interpretation of elevation measurements in peatlands, in order to predict carbon dioxide emissions or uptake caused by microbial decomposition or peat formation. This study gives a comprehensive overview of shrinkage studies carried out in the last 100 years. Terminology and approaches are systematically classified. In part I, the concepts for shrinkage characteristics, measurement methods, and model approaches are summarized. Part II is a meta‐analysis of shrinkage studies on peat and other organic soils amended by own measurement data obtained by a three‐dimensional structured light scanner. The results show that maximum shrinkage has a wide range from 11% to 93% and is strongly affected by common soil properties (botanical composition, degree of decomposition, soil organic carbon, and bulk density). Showing a stronger correlation, bulk density was a better predictor than soil organic carbon, but maximum shrinkage showed a large spread over all types of peat and other organic soils and ranges of bulk density and soil organic carbon.
More on affine Dynkin quiver Yangians
Authors: Bao Jiakang 
Published: July 2023

Abstract
We consider the quiver Yangians associated to general affine Dynkin diagrams. Although the quivers are generically not toric, the algebras have some similar structures. The odd reflections of the affine Dynkin diagrams should correspond to Seiberg duality of the quivers, and we investigate the relations of the dual quiver Yangians. We also mention the construction of the twisted quiver Yangians. It is conjectured that the truncations of the (twisted) quiver Yangians can give rise to certain 𝒲-algebras. Incidentally, we give the screening currents of the 𝒲-algebras in terms of the free field realization in the case of generalized conifolds. Moreover, we discuss the toroidal and elliptic algebras for any general quivers.
The Linear CS/WZW Bulk/Boundary System in AQFT
Authors: Benini Marco , Grant-Stuart Alastair , Schenkel Alexander 
Published: July 2023

AbstractThis paper constructs in the framework of algebraic quantum field theory (AQFT) the linear Chern–Simons/Wess–Zumino–Witten system on a class of 3-manifolds M whose boundary $$\partial M$$

∂
M

is endowed with a Lorentzian metric. It is proven that this AQFT is equivalent to a dimensionally reduced AQFT on a 2-dimensional manifold B, whose restriction to the 1-dimensional boundary $$\partial B$$

∂
B

is weakly equivalent to a chiral free boson.
Derivations and KMS-Symmetric Quantum Markov Semigroups
Authors: Vernooij Matthijs , Wirth Melchior 
Published: July 2023

AbstractWe prove that the generator of the $$L^2$$

L
2

implementation of a KMS-symmetric quantum Markov semigroup can be expressed as the square of a derivation with values in a Hilbert bimodule, extending earlier results by Cipriani and Sauvageot for tracially symmetric semigroups and the second-named author for GNS-symmetric semigroups. This result hinges on the introduction of a new completely positive map on the algebra of bounded operators on the GNS Hilbert space. This transformation maps symmetric Markov operators to symmetric Markov operators and is essential to obtain the required inner product on the Hilbert bimodule.
Almost complex parallelizable manifolds: Kodaira dimension and special structures
Authors: Cattaneo Andrea , Nannicini Antonella , Tomassini Adriano 
Published: July 2023

AbstractWe study the Kodaira dimension of a real parallelizable manifold M, with an almost complex structure J in standard form with respect to a given parallelism. For $$X = (M, J)$$

X
=
(
M
,
J
)

we give conditions under which $${{\,\textrm{kod}\,}}(X) = 0$$

kod

(
X
)
=
0

. We provide examples in the case $$M = G \times G$$

M
=
G
×
G

, where G is a compact connected real Lie group. Finally we describe geometrical properties of real parallelizable manifolds in the framework of statistical geometry.
Gaps and Challenges in Harnessing the Benefits and Opportunities of Indigenous Certification for a Sustainable Communal Commercial Lobster Fishery
Authors: Elegbede Isa , Zurba Melanie , Hameed Ahmad , Campbell Chelsey 
Published: July 2023

AbstractThe Marshall Decision of Canada’s Supreme Court inspired the Mi’kmaq in the 1700s regarding recognizing fishing rights to the Mi’kmaq communities. Despite this recognition, the Mi’kmaq communities did not have access to commercial fisheries due to the denial of absolute recognition of territories and rights and underrepresentation and participation in resource allocation, governance, and decision-making processes. A potential approach to these issues is the development of third-party Indigenous community-based sustainability certification standards for the American lobster (Homarus americanus) commercial fishery of Nova Scotia by Mi’kmaq communities. An Indigenous certification is a market-based tool that focuses on a holistic approach to the sustainability of the resource, followed by independent accreditations and standards. This study identifies the gaps, challenges, and opportunities of Indigenous-based certifications for the American lobster commercial fishery. We adopt a participatory approach to conventional policy analysis and perform a secondary analysis of existing legal and scientific resources to glean valuable information for supporting the establishment of an Indigenous certification for the American lobster. Certification could provide benefits such as increased control over fisheries management, governance, rights, and socioeconomic interest, building capacity for Mi’kmaq communities, and improving stakeholder relationships. However, there are issues with the entry points of certification for Indigenous peoples related primarily to the dominant actors in accreditation. This study will support further research and engagement of the Mi’kmaq people toward developing an Indigenous certification scheme.
Quantitative evaluation of corneal irregularity and scarring after infectious keratitis using anterior segment optical coherence tomography
Authors: Ichikawa Kazunori , Ono Takashi , Chen Lily , Kitamoto Kohdai , Taketatni Yukako , Toyono Tetsuya , Yoshida Junko , Aihara Makoto , Miyai Takashi 
Published: July 2023

Abstract
Purpose
Corneal scars after infectious keratitis lead to insufficient transparency and irregular astigmatism, affecting visual acuity; therefore, they should be accurately evaluated to estimate visual function. This study aimed to quantitatively evaluate corneal irregularity and scarring after infectious keratitis using anterior segment optical coherence tomography (AS-OCT).

Methods
This was an observational clinical study. We included patients who had corneal scarring after treatment of infectious keratitis between 2014 and 2021 at University of Tokyo Hospital. We retrospectively examined best spectacle-corrected visual acuity (BSCVA), average keratometric power, central corneal thickness (CCT), and four components of the Fourier harmonic analysis including spherical and asymmetry components, as well as regular astigmatism and higher-order irregularity. We included anterior and posterior corneal data and compared results with those of contralateral healthy eyes. Additionally, we quantitatively evaluated the densitometry of the cornea obtained using AS-OCT.

Results
A total of 122 eyes of 61 patients were examined; male predominance was observed (n = 37), and the mean patient age was 55.3 ± 19.4 years. Comparisons with contralateral healthy eyes showed that BSCVA worsened (0.30 ± 0.83 and 0.93 ± 1.36 logMAR, respectively, P = 0.003), and CCT (531.1 ± 46.2 and 591.8 ± 132.4 μm, respectively, P < 0.001) and corneal densitometry (84.4 ± 11.8 and 111.9 ± 19.2 grayscale units, respectively, P < 0.001) increased significantly in affected eyes. The asymmetry component and higher-order irregularities that were not corrected with spectacles significantly increased (both P < 0.001), and there were no significant differences in the changes among the bacterial, fungal, herpetic, and acanthamoeba types of keratitis.

Conclusion
Corneal scarring persisted after treatment for infectious keratitis, and the asymmetry and irregularities of corneal astigmatism increased as visual acuity deteriorated. AS-OCT with the Fourier harmonic analysis was useful for evaluating corneal topographic changes in patients with corneal scarring after keratitis.
Changes in anxiety and depression among public health workers during the COVID-19 pandemic response
Authors: Stone Kahler W. , Jagger Meredith A. , Horney Jennifer A. , Kintziger Kristina W. 
Published: July 2023

Abstract
Objectives
The COVID-19 pandemic has negatively impacted mental health indicators, leading to an increase in symptoms of anxiety and depression in both the general population of adults and children and many occupational groups. This study aims to examine changes in anxiety and depression among a cohort of public health workers in the U.S. during the first year of the COVID-19 pandemic and identify potential risk factors.

Methods
Longitudinal data were collected from a sub-sample (N = 85) of public health workers in 23 U.S. states who completed two surveys in 2020 and 2021. Information on background characteristics, personal well-being, and work environment as well as validated scales to assess generalized anxiety disorder (GAD), depressive disorder, and burnout was collected. Data were analyzed using Stata Version 17, and significant differences were determined using Pearson’s Chi2 and Fisher’s Exact tests.

Results
The proportion of those reporting GAD (46.3% to 23.2%) or depression (37.8% to 26.8%) improved from Survey 1 to Survey 2 overall; symptoms of anxiety saw the largest improvement. Persistent depression was associated with sustained burnout, changes in social support, and days worked per week.

Conclusion
Public health workers experienced elevated levels of anxiety and depression during the initial pandemic response, but a reduction in these symptoms was observed in the subsequent year after vaccines had become widely available. However, unmet needs remain for ongoing workplace mental health supports to address burnout, as well as for additional emotional supports outside of work for public health professionals.
Perivascular epithelioid cell tumors (PEComas) of the bone and soft tissue: a Japanese Musculoskeletal Oncology Group (JMOG) multi-institutional study
Authors: Izubuchi Yuya , Hamada Shunsuke , Tanzawa Yoshikazu , Fujita Ikuo , Imanishi Jungo , Koyanagi Hirotaka , Shimatani Akiyoshi , Komatsubara Tadashi , Tanaka Takaaki , Fukushima Mana , Imamura Yoshiaki , Ueda Takafumi , Kawano Hirotaka , Matsumine Akihiko 
Published: July 2023

Abstract
Purpose
Perivascular epithelioid cell tumors (PEComas) of the bone and soft tissues are rare mesenchymal neoplasms, some of which are malignant. However, their clinical and pathological characteristics remain unclear. This study was performed to investigate the clinical and pathological characteristics of PEComas in bone and soft tissues by leveraging information from the Japanese Musculoskeletal Oncology Group.

Methods
Nine patients, including four male and five female patients with a median age of 50 years, were retrospectively reviewed. PEComas of the visceral organs, including the uterus and retroperitoneum, were excluded.

Results
Eight tumors arose in the soft tissue and one in the bone, with a mean size of 8.8 cm. Four patients showed local recurrence or distant metastasis. The 1-year survival rate was 78%. Pathologically, eight tumors were classified as malignant and one as having uncertain malignancy potential. Half of the tumors showed high MIB-1 index values of > 30%. Immunohistochemically, the melanocyte marker HMB45 was expressed in 89% of the cases, and muscle-specific markers were expressed only in 30–50% of the cases. Transcription factor binding to IGHM enhancer 3 (TFE3) expression was positive in 100% of the patients. Tumors with high expression of TFE3 were classified as PEComas with malignant potential according to Folpe’s classification.

Conclusions
Bone and soft tissue PEComas may have a higher malignancy potential than other visceral PEComas and are more likely to develop as TFE3-rearranged PEComas.