bluuebunny/crossref_metadata_2025_split huggingface dataset:
Health‐related quality of life in people with HIV from the multicentre CoRIS cohort in Spain: Associated factors and short‐term changes over time
Authors: Izquierdo Rebeca , Suárez‐García Inés , Marco‐Sánchez Cristina , Pérez‐Latorre Leire , Riera Melchor , Cano Joanna , Viladés Consuelo , Reus Sergio , Olalla Julián , González‐Ruano Patricia , Orviz Eva , Díaz Asunción , Moreno Santiago , Jarrín Inma ,   CoRIS cohort
Published: January 2025

AbstractObjectivesWe aimed to describe health‐related quality of life (HRQoL), overall and across its dimensions, identify associated factors, and assess changes over time among people with HIV (PWH) from the Spanish multicentre CoRIS cohort.MethodsWe developed a mobile app to collect HRQoL data every 3 months using the WHOQOL‐HIV‐BREF questionnaire (31 items across six domains), among PWH followed in CoRIS in 2021–2023. Factors associated with good/very good global HRQoL and with domain‐specific mean scores were identified using multivariable logistic and linear regression, respectively.ResultsOf 414 PWH (94.2% on antiretroviral treatment, 91.1% virally suppressed), 51.2% reported good/very good HRQoL. Latin American migrants (adjusted OR: 0.60 [95% CI: 0.36; 1.00]), and participants with lower educational level (0.36 [0.21; 0.64]), a previous AIDS diagnosis (0.56 [0.29; 1.11]) and a history of non‐AIDS‐related cancers (0.40 [0.14; 1.14]) were less likely to report good/very good global HRQoL. The most affected items included sexual satisfaction, forgiveness and blame, sleep and rest, and concerns about the future, with spirituality, religion and personal beliefs as the most affected domain. Latin American origin, lower educational level and shorter (<2 years) or longer (>15 years) time since HIV diagnosis were associated with poorer HRQoL in specific domains. No significant changes in HRQoL were observed after 12 months except slightly higher scores in physical health.ConclusionsOnly half of PWH reported good/very good global HRQoL. This highlights the need to develop targeted strategies to improve HRQoL among PWH, focusing on addressing the most affected dimensions and supporting the most vulnerable groups.
Perceptions of Mental Health Challenges and Needs of Indonesian Adolescents: A Descriptive Qualitative Study
Authors: Yani Desy Indra , Chua Joelle Yan Xin , Wong John Chee Meng , Pikkarainen Minna , Goh Yong Shian Shawn , Shorey Shefaly 
Published: January 2025

ABSTRACTIndonesian adolescents face an increased risk of developing mental health conditions such as depression and anxiety, largely due to insufficient mental health literacy and awareness. This lack of knowledge often leads to delayed recognition and treatment. To address this, the present descriptive qualitative study explores Indonesian adolescents' perceptions of mental health challenges and needs. Fourteen adolescents from two public schools in Indonesia were selected through purposive sampling based on their mental health literacy scores (either high or low). One‐on‐one semi‐structured interviews were conducted in December 2023, and thematic analysis was used to uncover key patterns and themes. The study follows the consolidated criteria for reporting qualitative research guidelines. Three main themes emerged: (1) Transitioning to Adulthood: Journeys Through Emotional Turmoil and Societal Expectations, (2) Navigating Challenges: Diverse Adolescent Responses and (3) Breaking the Silence: Empowering Adolescents Through Comprehensive Mental Health Education and Support. This study found that adolescents faced specific challenges related to emotional regulation, body image and self‐esteem, academic pressure and the influence of social media. In response to these difficulties, they employed various coping mechanisms, both adaptive and maladaptive. Despite the adversities, adolescents expressed a strong desire to learn how to better manage these challenges and pursue their future career goals. These findings highlight the importance of developing culturally appropriate mental health education and support programs for Indonesian adolescents. Future studies should include a more diverse sample of adolescents and incorporate perspectives from parents and educators to gain a more comprehensive understanding of adolescent mental health in Indonesia.
Clinicians Perspectives on Effective Suicide Prevention in Secondary Care Adult Mental Health Services: An Appreciative Inquiry Approach
Authors: Holland P. , Haldane S. , Kake T.R. 
Published: January 2025

ABSTRACTSuicide is a major health issue with devastating consequences for individuals, families and communities. In New Zealand, the latest confirmed suicide rates show an increase, with young adults, males and members of the indigenous Māori and LGBTQIA+ communities particularly affected. Until recently, most of the suicide research in New Zealand focused on the general population, rather than clinical populations such as those accessing mental health services. This evidence gap is especially important in New Zealand where almost half of those who die by suicide have known involvement with mental health services. The present qualitative study explored the question: What strategies and approaches do clinicians consider effective for preventing suicide in people accessing adult secondary care community mental health services? Eleven clinicians from a large metropolitan service were interviewed individually and in a focus group. Appreciative inquiry and thematic analysis were used. This report is adherent with COREQ. Four themes were identified for suicide prevention: Understanding who the person is, and for Indigenous Māori, this included use of cultural practices; providing a range of evidence‐based prevention strategies; having an effective service structure that is part of a wider system; and suicide prevention work is important and staff need effective support. Clinicians identified strategies at the individual, family and service level for preventing suicide, most of which aligned with those recommended in the literature. There is a need for more suicide prevention research in secondary care mental health services and the effectiveness of suicide prevention in high‐rate groups such as Māori and LGBTQIA+.
Developing and Testing a Reflection Method for Implementation of a Professional Reporting Guideline in Community Nursing: Design‐Based Research
Authors: Vullings Nicole , Heinen Maud , Adriaansen Marian , Vermeulen Hester , Van Der Wees Philip , Maas Marjo 
Published: January 2025

ABSTRACTAimTo develop a reflection method for community nurses and certified nursing assistants to support the implementation of a professional reporting guideline for nurses and certified nursing assistants in daily care and to identify its key features.DesignDesign‐based research.MethodsThis study was conducted in the Netherlands from February 2021 to April 2022. The reflection method was developed by a design group (community nurses, certified nursing assistants and a patient representative) and four test groups of nurses. Experiences of participants were explored with video recordings and observational notes from test group meetings. The data were thematically analysed to refine the reflection method and identify key features.ResultsA final reflection method was developed. We identified three main themes: (1) Impact on behaviour change, (2) group learning and (3) conditional factors for critical reflection. Seven key features emerged as essential, forming the building blocks of the reflection method: focus on critical reflection, allocate time to formulate themes, include participants from various backgrounds and organisations, ensure the group is appropriately sized, allow for sufficient time, keep it simple and attractive and stimulate the group to make the transfer of learning to their clinical practice.ConclusionsThe final method included two 2 h meetings with up to six participants and a coach. Participants learned from critical reflection and feedback to improve the reporting quality and critical assessment of daily practices, especially from colleagues with varying team affiliations and educational backgrounds.ImpactThis reflection method enables community nurses and certified nursing assistants to learn collaboratively, aligning with the ‘Nursing and Caring Reporting’ guideline and bridging the gap between research and clinical practice.Report MethodThe COREQ guideline was used.Patient or Public ContributionThe study design facilitated close collaboration among researchers, community nurses, certified nursing assistants and clients.
Visualization of Right Adrenal Vein in Non‐Contrast‐Enhanced MDCT and Its Guiding Role for Right Adrenal Venous Sampling
Authors: Xiong Hong‐liang , Du Li , Yang Jiao , Hu Wei‐Tong , Huang Jia‐Bing , Li Yun‐De , Chen Xi , Dong Yi‐Fei 
Published: January 2025

ABSTRACTThis study aimed to evaluate the visualization of right adrenal vein (RAV) in non‐contrast‐enhanced multi‐detector computed tomography (MDCT) and its guiding role for right adrenal venous sampling (AVS) in patients with primary aldosteronism (PA). A total of 237 patients diagnosed with PA who underwent successful AVS procedures from January 2020 to March 2021 were retrospectively analyzed. The non‐contrast‐enhanced MDCT image features of RAV included the degree of visualization and the position of RAV orifice. Subsequently, the concordance degree between RAV in non‐contrast‐enhanced MDCT and AVS images was calculated to evaluate its guiding effect for right AVS. The visualization rate of RAV in non‐contrast‐enhanced MDCT was 81.9% (n = 194), with 73.7% (n = 143) clearly displayed and 26.3% (n = 51) generally displayed. In 6.2% (n = 12) of patients who can display RAV, RAV formed a common trunk with the accessory hepatic vein and then merged into the inferior vena cava. Non‐contrast‐enhanced MDCT revealed that RAV orifice was located between the 10th thoracic vertebra (T10) and the 1st lumbar vertebra (L1), with 85.1% (n = 165) located from the lower 1/3 of T11 to the lower 1/3 of T12. The concordance of imaging anatomy of RAV between non‐contrast‐enhanced MDCT and AVS image was found to be at a high rate of 94.3% (n = 183). Non‐contrast‐enhanced MDCT provides excellent visualization of RAV and clearly depicts its anatomical characteristics. Furthermore, RAV images obtained from non‐contrast‐enhanced MDCT are highly consistent with those from AVS, indicating that interpretation of non‐contrast‐enhanced MDCT before AVS can reduce the failure rate of RAV cannulation.
Occipital bone modeling patterns during the first years of life: A preliminary histological and quantitative approach
Authors: Lozano‐Bendicho Cristina , Sánchez‐Andrés Ángeles , Martínez Ignacio , Conde‐Valverde Mercedes , Carretero José‐Miguel , Rodríguez Laura , Cirotto Nico , García‐González Rebeca 
Published: January 2025

AbstractStudies of modeling processes have provided important insights in human evolutionary discipline. Most of these studies are based on facial bones and in much lesser extent on other bones such as those from the cranial vault. Thus, this study fills a gap in research by examining occipital bone modeling in subadults, adding individuals under 2 years old and expanding the sample size available to date. The sample comprise 14 subadults occipitals (4 months to 5 years) from archeological sites spanning the thirteenth to the eighteenth century. Resin replicas coated with gold were elaborated to examine the modeling patterns using scanning electron microscopy and the results of this analysis are illustrated in the modeling maps. The percentages of deposition and resorption were calculated to enable the comparison of the modeling patterns between individuals. The analysis unveiled a pattern of resorption predominance in younger individuals, shifting to deposition around 3 years old before reverting to resorption in older individuals. Symmetry in modeling processes between left and right halves of the occipital was observed, suggesting stability in bone modeling. Comparisons with previous studies showed variations in modeling patterns influenced by factors like age. Overall, this study sheds light on occipital bone modeling processes, highlighting the importance of sample size and quantitative analysis in the interpretation of modeling maps. Further research is justified to comprehensively explore occipital modeling patterns, particularly during the early stages of development.
Muscular anatomy of the forelimb of Leopardus geoffroyi: Functional and phylogenetic aspects in Feliformia, part I. Proximal forelimb
Authors: Cardozo Sergio A. , Morales Miriam M. , Ercoli Marcos D. , Aguado Luis I. , Ortiz Tejerina Agustina M. 
Published: January 2025

AbstractAnatomical knowledge is fundamental for all species. In particular, myology allows a deeper understanding of ecomorphology—especially for those species hard to observe in the wild—and may be an important source for phylogenetic information. In this study, we analyzed the myological variation of the musculature of the shoulder and arm of the forelimb in species of the suborder Feliformia and its relationship with the phylogenetic history and the locomotor behavior, habitat, and predatory habits of the species within this group, using Leopardus geoffroyi as a case study. We used gross‐anatomy dissections of the shoulder and arm of three specimens of L. geoffroyi and contrasted these results to other previously described feliform species. Additionally, we optimized 15 myological characters to search for phylogenetic patterns. We present the first description and the first complete muscular maps of the forelimb shoulder and upper arm of L. geoffroyi. A small number of muscular characteristics allow L. geoffroyi to be distinguished from other feliforms, such as a possible partial division of m. biceps brachii, although they did not relate to any analyzed ecological habit. Some myological characteristics studied in this work contribute to the knowledge of the phylogenetic relationships and the morphological evolution of Feliformia. Felids are the only feliforms with a constantly present m. pectoantebrachialis (although it has been reported in some caniforms). Muscle rhomboideus capitis is present only in Felidae and Herpestidae, resembling various caniforms. Its presence could indicate a retention linked to their carnivoran ancestry. The Felidae and Hyaenidae represent two quite conservative morphotypes, as they present particular muscular configurations compared to other feliform families, but also, relatively little variation within each family. Functionally, some myological characters recorded in hyenids, L. lynx, P. uncia, A. jubatus (e.g., radio‐ulnar insertion of m. biceps brachii), distinguish them from the rest of the species of the same suborder or family, and are convergent with other carnivorans with cursorial habits (e.g., canids). The functional and evolutionary analysis of the myology of the forelimb of L. geoffroyi and the different species of the suborder Feliformia allowed a better understanding of how muscle configurations reflect functional specialization to different ways of life. The muscle maps presented here, being the first available for a small Neotropical felid, can be considered a valuable source of information, useful for future studies of comparative anatomy in neontological and paleobiological contexts.
Nutritional value and biochemical composition of two new tropical polychaete species: Potential use as feed ingredients
Authors: Wang Xi , Sui Zhihui , Xu Xiaojuan , Chai Yanchao , Wang Haiqing 
Published: January 2025

AbstractPolychaetes are a promising intertidal resources due to their widespread distribution, considerable biomass, and high nutrition value. The nutritional profiles of two novel tropical polychaetes species (Marphysa sp. and Halla sp.) were determined. Additionally, comparing nutritional levels of polychaetes with other species and requirements of main aquatic animals, this study aimed to explore their potential as aquaculture feed ingredients. The results revealed that both polychaetes species are nutrient‐rich with significant interspecific variation. Marphysa sp. showed higher protein, total essential amino acid (EAA) ratio (17.32 ± 0.46 mg/g), lipid, eicosapentaenoic acid (EPA; 10.99%), α‐Linolenic acid (ALA; 1.25%), ash and energy content compared to Halla sp. (p < 0.05). Conversely, Halla sp. had a significantly higher docosahexaenoic acid (DHA; 5.68%) index compared to Marphysa sp. (DHA; 2.57%). Meanwhile, the levels of macroelements (K, Ca, Na) and trace elements (Mg, Mn, Cu) also exhibited differences in the two species. Compared with other polychaetes and aquatic feed, both Marphysa sp. and Halla sp. are promising high‐quality feed ingredients, as they contain high levels of minerals, essential amino acids, and beneficial lipid profiles. This study will support the identification of alternative substitutes to meet the growing demand for aquafeed ingredients.
Governance framework for access and benefit sharing in the Hindu Kush Himalayan region
Authors: James Nishmma , Thiruthy Narendran 
Published: January 2025

AbstractThe Hindu Kush Himalayas (HKH) are of global significance, characterised by immense ecological, cultural, and biological importance spanning over eight South Asian countries. The region is home to a vast repository of genetic resources (GR) and traditional knowledge (TK) that transcend geopolitical boundaries, rendering them prone to uncompensated bioprospecting. The transboundary nature of these resources presents challenges for ensuring fair and equitable sharing of benefits and preventing biopiracy. To safeguard biodiversity and protect the interests of local communities, effective access and benefit sharing (ABS) measures need to be put in place. Therefore collaborative efforts of the countries in the region are crucial. This paper tries to elucidate the complexities inherent to the region and analyse the existing international and national legal framework to address ABS and collaboration between the countries when it comes to transboundary GR and associated TK. An attempt is also made to identify a possible solution within the current legal regime under the Convention on Biological Diversity (CBD) framework.
Dietary fats and cardiometabolic health—from public health to personalised nutrition: ‘One for all’ and ‘all for one’
Authors: Lovegrove Julie Anne 
Published: January 2025

AbstractThis paper provides a summary of the 2023 British Nutrition Foundation Annual Lecture by Professor Julie Lovegrove. Professor Lovegrove is the head of the Hugh Sinclair Unit of Human Nutrition at the University of Reading. Professor Lovegrove, who was nominated for the BNF Prize for her outstanding contribution to nutritional sciences has published over 300 scientific papers and made a major contribution to establishing the relevance of dietary fat quality in the development and prevention of cardiometabolic disease.
Measure Subtrochanteric Osteotomy in Unilateral Crowe‐IV Dysplasia‐Surgical Technique
Authors: Zhao Runkai , Wang Yiming , Liu Te , Ren Haichao , Zhao Runzhi , Feng Zeyu , Li Pengcheng , Yang Shuai , Lu Juntao , Fan Menglin , Ji Quanbo , Zhang Guoqiang 
Published: January 2025

ABSTRACTObjectiveDetermining the optimal osteotomy length for patients with unilateral Crowe‐IV developmental dysplasia of the hip undergoing subtrochanteric osteotomy remains challenging due to the significant variability in pelvic and spinal alignment. Incorrect osteotomy length, compounded by pelvic or spinal tilt, can adversely affect postoperative gait and long‐term outcomes. Therefore, this study could introduce a method to calculate the osteotomy length for patients with unilateral Crowe‐IV developmental dysplasia of the hip, correcting spinal and pelvic tilt, and improving patient gait.MethodsThis is a retrospective study that included 28 patients with unilateral Crowe‐IV developmental dysplasia of the hip collected from June 2019 to June 2020, who underwent total hip arthroplasty with measured subtrochanteric osteotomy technique. The average follow‐up period was 4.3 years (last follow‐up). Harris scores, pelvic tilt angles represented by iliac obliquity angle (IO) and sacral obliquity angle (SO), and postoperative complications were recorded. Statistical analysis was performed using independent sample t‐tests for normally distributed data and the Mann–Whitney U test for non‐normally distributed data.ResultsPostoperatively, pelvic tilt angles improved significantly. The comparison of preoperative and postoperative 3‐month IO angles (8.77° ± 3.31° vs. 5.28° ± 2.29°, p = 0.00), and postoperative 3‐month and last follow‐up (5.28° ± 2.29° vs. 2.88° ± 1.39°, p = 0.00) showed statistically significant differences. Similarly, the comparison of preoperative and postoperative 3‐month SO angles (9.56° ± 3.1° vs. 5.81° ± 2.78°, p = 0.00), and postoperative 3‐month and last follow‐up (5.81 °± 2.78° vs. 3.59° ± 1.72°, p = 0.00) showed statistically significant differences. Harris scores significantly improved from preoperative to 1‐year postoperative (47.35 ± 12.32 vs. 80.5 ± 7.81, p = 0.00), and from 1‐year postoperative to last follow‐up (80.5 ± 7.81 vs. 90.78 ± 2.86, p = 0.00) with statistical significance. There were no significant differences in adverse event rates between the two groups.ConclusionTotal hip arthroplasty combined with measurement subtrochanteric osteotomy technique improves pelvic tilt and Harris scores in Crowe‐IV developmental dysplasia patients. This technique may serve as a guideline for determining resection length.
Starting and Stopping Wars
Authors: Lang Gerald 
Published: January 2025

ABSTRACTIf a warring side may fight in pursuit of an aim up to some proportionality‐respecting limit, then an important question is whether that side is morally required to stop fighting when it reaches that limit, despite not yet having attained its aim. The ‘Quota View’ answers this question affirmatively, while other views hold that the fighting may continue just as long as the projected future losses fall within certain limits. I criticize some of these other views, as well as a further argument that can be distilled from these sources, and advance a qualified version of the Quota View.
Spatial and Temporal Regulation of Flower Coloration in Cymbidium lowianum
Authors: Dong Xiu‐Mei , Zhang Wei , Tu Mengling , Zhang Shi‐Bao 
Published: January 2025

ABSTRACTFlower color is a crucial trait that attracts pollinators and determines the ornamental value of floral crops. Cymbidium lowianum, one of the most important breeding parent of Cymbidium hybrids, has two flower morphs (normal and albino) that differ in flower lip color. However, the molecular mechanisms underlying flower color formation in C. lowianum are not well understood. In this study, comparative metabolomic analysis between normal and albino flower lip tissues indicated that cyanidin‐3‐O‐glucoside content was significantly higher in red epichiles than in other lip tissues. This finding suggests that cyanidin‐3‐O‐glucoside is responsible for color variation and differentiation in the lip in C. lowianum. We also found that red coloration in C. lowianum flower is correlated with high levels of F3'H expression; further, anthocyanins, carotenoids and chlorophyll coordinate to influence sepal and petal coloration during flower development. In transgenic Arabidopsis lines, overexpression of F3'H increased anthocyanin concentration, overexpression of BCH increased carotenoid concentration, whereas overexpression of HEMG and CHLI both increased chlorophyll concentration. Identification and assessment of several transcription factors revealed that MYB308‐1 activates BCH, MYB111 and PIF4‐2 activate HEMG and CHLI expression during flower development. Importantly, MYB14‐1 shows interaction with PIF4‐2, and appears to act as a connector between anthocyanin and chlorophyll biosynthesis by either activating F3'H expression or inhibiting CHLI expression. These results indicate that, in C. lowianum, variation in flower color and differentiation of lip color patterns are primarily regulated by the types and concentrations of flavonoids; further, carotenoids and chlorophyll also influence flower coloration during development.