bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of the Storm Water Volume Control Target in Ontario
Authors: Singh Gautam 
Published: August 2023

<p>This study evaluates the “proposed stormwater volume control target in Ontario,” which is set at the 90 percentile of rainfall event volume, in terms of a) the percentage of total rainfall volume- controlled; b) the effectiveness of using low-impact-development (LID) measures for a development site to meet the proposed target. Based on the analyses of daily and hourly rainfall data from 122 hydrological stations in Ontario, the total rainfall volumes corresponding to daily and hourly 90th percentile rainfall depth were computed to be approximately 68% and 79%, respectively. Using a hydrologic model of a hypothetical catchment of 100m by 100m, it was determined that it would be difficult to retain 90% of the total rainfall volume on-site by applying a LID designed to retain 90 percentile rainfall event volume. </p>
Development of a Quick Design Method for Composite Concrete Slab-Over Steel Box Girder Bridges for Project Bidding
Authors: Duhig Megan 
Published: August 2023

<p>In bridge analysis, the beam analogy method is used to analyze girders for the longitudinal load effects of live loads. Designers calculate the maximum bending moment (MT), and the shear force (VT), of a bridge girder under truck loading and use the truck load fraction (FT) to generate the design longitudinal live load effects. This Report presents structural analysis and design of different composite concrete slab-over multi-spine steel box girder configurations subjected to CL-W truck loading. Bridge geometries include single-, two-, three-, and four-span girder arrangements. Bridge widths ranged from 7 m (1 lane) to 24 m (6 lanes), with spans ranging from 20 m to 80 m. Equations developed by others were used to represent values of the maximum shear, deflection and bending moments experienced by the girder due to truck loading conditions. This study also included updating and verification of a software developed by a Ph.D. student, used to perform composite steel box girder design. The software optimizes the box girder size based on the CHBDC design procedure. Using the developed software, a parametric study was conducted to determine the required moment of inertia of the bare steel section, composite moment of inertia and steel web area to satisfy all design requirements. Empirical equations for these three properties were developed to assist bridge designers in estimating steel box girder section sizes for contract bidding. </p>
The Structural Performance of Composite Slabs with Profiled Steel Sheet Incorporating Different Concretes
Authors: Mahfuz Marjuk 
Published: August 2023

<p>Cold formed profiled steel sheets are widely used for composite floor decking, where they remain permanently in place as an integral part of the floor system. Some benefits of composite deck flooring are economy, speed of construction, and reduced weight. This research consisted of experimental investigations on composite slabs under static and post-fatigue monotonic loading, as well as loading to failure after being subjected to fire at specified temperature and fire duration. The material and geometric variables are the five types of high performance concrete mixes, two types of profile sheet and the presence or absence of longitudinal reinforcement. The structural performance of the composite slabs are described based on load-displacement response, stiffness, energy absorption capacity, ductility, steel deck-concrete interface as well as post-fatigue and post-fire residual strength. The recommendations of this research will be useful for determining the best application for each concrete mix in composite slabs. </p>
Robustness-Based Optimal Progressive Collapse Design of Reinforced Concrete
Authors: Praxedes Silva Neto Conrado 
Published: August 2023

<p>Progressive collapse of structures is a cascading failure phenomenon with a failure consequence that is disproportionate to the direct damage of an initiating event. The Ronan Point Building collapse in 1968 triggered the start of research on disproportionate progressive collapse in building structural engineering. Intense research was followed after the Alfred P. Murrah Federal Building bombing in 1995 and the disastrous collapse of the World Trade Centre after aircraft strikes. </p>
<p>Progressive collapse has essentially two distinct features: system- rather than component-level responses, and low probability and high consequences. The majority of existing design codes and standards consider progressive collapse implicitly, by improving the performance of a structure through the specification of minimum levels of strength, continuity, and ductility. On the other hand, existing explicit design procedures largely consist of a component-based design approach. </p>
<p>This study proposes an innovative system-based and risk-informed decision making framework for progressive collapse design of reinforced concrete frames. Considering the full spectrum of risk due to initiating events, a novel risk-based robustness index is proposed as a system-level performance criterion for design. From a conventionally designed structure, an optimization pro- cess identifies optimal allocation of resources that results in a robust system. An efficient design frontier is defined based on optimal designs when varying the additional expenses provided for the improvement of robustness of a structure. The efficient frontier is then used to verify the cost effectiveness of the design alternatives in conjunction with the cumulative prospect theory. </p>
<p>In order to assist in the decision-making process of progressive collapse design provisions, a risk-cost trade-off framework is proposed. The design framework establishes whether additional resources must be used to enhance the robustness of a structure, and when required, it further identifies the optimal expenses that should be used to prevent potential progressive collapse. </p>
A Hybrid Spatial Adaptive Modulation and Frequency Stochastic Approach for MU-MIMO-OFDM Systems in the Context of Underlay Cognitive Radios
Authors: Labdaoui Rym , Ghanem Khalida , Ettoumi Fatiha Youcef 
Published: August 2023

In this paper, low complexity rate and power optimization schemes operating in the spatial and frequency domains are proposed in a cognitive radio (CR) setting involving multi-user multiple-input-multiple-output-orthogonal frequency division multiplexing (MU-MIMO-OFDM). Under the assumption of a perfect secondary channel state information (CSI) at the receiver, the presented architectures encompass two main stages. In the first one, spatial power waterfilling-like method is performed per each MIMO subchannel pertaining to each subcarrier of each secondary user (SU). The resulting allocated power per each eigen-channel is considered as the power budget in the second stage. In this latter, stochastic algorithm-based approach wherein the transmit parameters per each subcarrier of each SU are adapted such that to maximize the achievable sum-rate capacity of the SUs. Three different schemes are introduced in this work. First, the derivation of the continuous rate MU-MIMO-OFDM-CR version, referred to as C-MU-MIMO-OFDM-CR is presented. Obviously, this proposition is theoretical and is taken as a benchmark for the two remaining counterparts. The second proposition we called discrete-rate MU-MIMO-OFDM-CR, and briefly designated as D-MU-MIMO-OFDM-CR which is to round the provided allocated rate. Finally, the third modified solution, denoted as P-D-MU-MIMO-OFDM-CR proceeds in a similar way as the D-MU-MIMO-OFDM-CR alternative, but superimposes the non/over-used amount of power to the power budget in next iteration. The simulation results show that, compared to the discrete rate D-MU-MIMO-OFDM-CR solution, the P-D-MU-MIMO-OFDM-CR approach exhibits an approximate power gain of 1 dB when the SNR level is low, and of 5 dB at high SNR range.
SOSIALISASI DAN EDUKASI TENTANG BAHAYA NARKOBA PADA MASYARAKAT PESISIR DI SMPN SATU ATAP TAPULAGA KECAMATAN SOROPIA
Authors: Nuralifah Nuralifah , Malaka Muhammad Hajrul , Arfan  , Parawansah  , Murniaty  , Mursyidah Apriatin  , Helma Yanda Serah  , Puteri Febriyanthi Rachman  , Sri Oktaviani  , Sofianti Tarta  , Sitti Fazrianti Saputri  , Wa Ode Nurmayanti  
Published: August 2023

Narkoba adalah singkatan dari narkotika, psikotropika dan bahan adiktif lainnya. Istilah lainnya adalah NAPZA (narkotika, psikotropika dan zat adiktif). Salah satu kelompok masyarakat yang rawan terpapar penyalahgunaan Narkoba yaitu pada rentang usia 15-35 tahun atau generasi milenial. Kelompok usia remaja justru memiliki keinginan yang besar untuk mencoba-coba, mengikuti trend dan gaya hidup, serta memilih hidup bersenang senang. Tujuan dari pengabdian ini yaitu dilakukannya kegiatan sosialisasi mengenai bahaya penyalahgunaan narkoba di Sekolah Menengah Pertama (SMP) Negeri Satu Atap Tapulaga untuk meningkatkan pemahaman tentang dampak yang ditimbulkan dari penggunaan narkoba, baik secara fisik, psikis maupun sosial ekonomi. Metode yang diberikan berupa informasi melalui penyuluhan, leaflet dan media sosial. Hasil dari kegiatan pengabdian yang telah dilakukan yaitu bertambahnya pengetahuan Siswa/Siswi SMPN Satu Atap Desa Tapulaga tentang bahaya penggunaan narkoba dan mendapatkan informasi yang jelas mengenai narkoba.
SOSIALISASI PEMAHAMAN TENTANG VCO (VIRGIN COCONUT OIL) DESA LEPPE, KECAMATAN SOROPIA, KABUPATEN KONAWE
Authors: Fristiohady Adryan , Yusuf Muhammad Ilyas , Pascayantri Asniar , Sahidin  , Muhamad Handoyo Sahumena  , Wahyuni  , Laode Muhamad Mbuyang Nadia  , Grasiana Eka E.Y.G  , Wa Ode Norma  , Yamin Yamin , Baka Wa Kuasa , Rianse Ilma Mustaqima 
Published: August 2023

Buah kelapa di wilayah pesisir Desa Leppe Kecamatan Soropia kabupaten Konawe, Provinsi Sulawesi Tenggara hanya dijual secara gelondongan. Tujuan pelatihan untuk memotivasi masyarakat agar berdaya dengan memanfaatkan potensi alamnya menjadi lebih ekonomis dan meningkatkan pemahaman tentang VCO Khalayak sasarannya adalah 20 orang masyarakat Desa Leppe. Kegiatan ini melibatkan mitra, baik dari pihak masyarakat yang bergiat di bidang pembuatan produk VCO, ibu-ibu penggerak Pemberdayaan Kesejahteraan Keluarga (PKK), Kegiatan pengabdian dilakukan melalui metode penyuluhan dan telah berlangsung dengan baik, lancar, serta mendapat respon yang positif dari para peserta. Transfer pengetahuan, baru ini telah memotivasi masyarakat untuk berwirausaha dengan membuat VCO murni bagi kesehatan tubuh seperti antibakteri, antivirus, dan anti jamur. Proses pembuatan VCO adalah dengan cara fermentasi tidak mengalami proses pemanasan dan tidak ada penambahan zat zat kimia. Diharapkan pelatihan ini ditindak lanjuti dengan pelatihan pembuatan produk VCO agar bisa dikemas dan bisa di perjual belikan.
Recidiva de los cánceres superficiales de vejiga posterior a quimioterapia intravesical con doxorrubicina
Authors: Pardina Salazar Ronald 
Published: August 2023

Introducción: El cáncer de vejiga es una enfermedad de gran prevalencia, siendo su mayor problema la tendencia a la recidiva y a la progresión. Para disminuir en lo posible esta recidiva y progresión se han utilizado muchos quimioterapéuticos intravesicales aplicados a lo largo de meses tras la resección transuretral de vejiga con resultados desiguales. La doxorrubicina es un antibiótico antraciclino con actividad antitumoral producido por Streptococcus peucetius var. caesius. Tiene la capacidad de intercalarse con el DNA, afecta muchas de sus funciones e inhibe la síntesis de DNA y RNA, que por vía intravesical actúa evitando la implantación de células tumorales circulantes.
Metodología: El estudio será de tipo observacional descriptivo, retrospectivo de corte transversal, comprendido entre el 1 de enero de 2018 y el 31 de enero de 2021 y desarrollado en el Servicio de Urología del Hospital Teodoro Maldonado Carbo.
Resultados: Fueron 148 casos analizados. La especificidad del índice fue de 81 %, con un valor predictivo (VP) positivo del 77 % y VP negativo de 68 %. La sensibilidad de la ascitis 85 % y la masa abdominal palpable del 79 %. En las pacientes que presentaron valores de antígeno CA-125 menor a 1000 U/ml, el riesgo de obtener una citorreducción óptima fue OR: 0.15 (IC95% 0.069 – 0.307; P: 0.0001); las pacientes que presentaron valores del índice de irresecabilidad entre 1 y 2 puntos versus 3 y 4 fue de OR: 7.04 (IC95% 3.33 -14.87, P: 0.0001).
Conclusiones: el cáncer de vejiga es una enfermedad prevalente que presenta desafíos significativos debido a su propensión a la recidiva y progresión. Para abordar este problema, se han utilizado diversos quimioterapéuticos intravesicales después de la resección transuretral de vejiga, aunque con resultados variables. La doxorrubicina, un antibiótico antraciclino con propiedades antitumorales, ha demostrado la capacidad de interferir con el ADN y el ARN, lo que la convierte en una opción valiosa para prevenir la implantación de células tumorales circulantes cuando se administra por vía intravesical.
A critical assessment of the Candida strains isolated from cigar tobacco leaves
Authors: Jia Yun , Zhou Wen , Yang Zhen , Zhou Quanwei , Wang Yue , Liu Yi , Jia Yuhong , Li Dongliang 
Published: August 2023

Introduction:Candida genus plays a crucial role in cigar fermentation, and strains from different sources might have differences in metabolic characteristics. Therefore, this study conducted directional isolation of Candida strains from cigar tobacco leaves and compared their fermentabilities to screen suitable strains for cigar fermentation, thereby improving the cigar quality.Methods: First, the Candida strains from cigars tobacco leaves in different production areas were directionally isolated by pure culture. Then, the isolated strains were screened based on chemical indexes and flavor component contents. Finally, the fermentabilities of preferred strains were verified by sensory evaluation.Results: Five strains of C. parapsilosis and four strains of C. metapsilosis were obtained through directional isolation. By comparing the physicochemical indexes of nine strains of Candida, it was found that C. parapsilosis P1 and C. metapsilosis M4 not only reduced the alkaloids content (by 25.3% and 32.6%, respectively) but also increased the flavor components content (by 25.2% and 18.9%, respectively). Among them, P1 could raise the content of chlorophyll degradation products, carotenoid degradation products, and Maillard reaction products, and enhance the beany and nutty flavor of cigars. M4 could raise the content of chlorophyll degradation products, cembranoids degradation products, and Maillard reaction products, and improve the baking, nutty, cocoa, and honey flavor of the cigar.Discussion: In this study, the Candida strains were directionally isolated from cigars tobacco leaves in different production areas, and two functional strains suitable for cigar fermentation were screened based on physicochemical indexes and sensory evaluation, which would contribute to the directed regulation of cigar quality and flavor diversification.
Gut microbiota dysbiosis characterized by abnormal elevation of Lactobacillus in patients with immune-mediated necrotizing myopathy
Authors: Liang Xiuping , Li Yanhong , Cheng Lu , Wu Yinlan , Wu Tong , Wen Ji , Huang Deying , Liao Zehui , Tan Chunyu , Luo Yubin , Liu Yi 
Published: August 2023

AimThe gut microbiota plays an important role in human health. In this study, we aimed to investigate whether and how gut microbiota communities are altered in patients with immune-mediated necrotizing myopathy (IMNM) and provide new ideas to further explore the pathogenesis of IMNM or screen for its clinical therapeutic targets in the future.MethodsThe gut microbiota collected from 19 IMNM patients and 23 healthy controls (HCs) were examined by using 16S rRNA gene sequencing. Alpha and beta-diversity analyses were applied to examine the bacterial diversity and community structure. Welch’s t test was performed to identify the significantly abundant taxa of bacteria between the two groups. Spearman correlation analysis was performed to analyze the correlation between gut microbiota and clinical indicators. A receiver operator characteristic (ROC) curve was used to reflect the sensitivity and specificity of microbial biomarker prediction of IMNM disease. P &lt; 0.05 was considered statistically significant.ResultsNineteen IMNM patients and 23 HCs were included in the analysis. Among IMNM patients, 94.74% (18/19) of them used glucocorticoids, while 57.89% (11/19) of them used disease-modifying antirheumatic drugs (DMARDs), and the disease was accessed by MITAX (18.26 ± 8.62) and MYOACT (20.68 ± 8.65) scores. Participants in the groups were matched for gender and age. The diversity of the gut microbiota of IMNM patients differed and decreased compared to that of HCs (Chao1, Shannon, and Simpson indexes: p &lt; 0.05). In IMNM patients, the relative abundances of Bacteroides, Roseburia, and Coprococcus were decreased, while that of Lactobacillus and Streptococcus were relatively increased. Furthermore, in IMNM patients, Lactobacillus was positively correlated with the levels of anti-signal recognition particle (SRP) antibodies, anti-Ro52 antibodies, and erythrocyte sedimentation rate (ESR), while Streptococcus was positively correlated with anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) antibodies and C-reactive protein (CRP). Roseburia was negatively correlated with myoglobin (MYO), cardiac troponin T (cTnT), ESR, CRP, and the occurrence of interstitial lung disease (ILD). Bacteroides was negatively correlated with ESR and CRP, and Coprococcus was negatively correlated with ESR. Finally, the prediction model was built using the top five differential genera, which was verified using a ROC curve (area under the curve (AUC): 87%, 95% confidence interval: 73%–100%).ConclusionWe observed a characteristic compositional change in the gut microbiota with an abnormal elevation of Lactobacillus in IMNM patients, which was accompanied by changes in clinical indicators. This suggests that gut microbiota dysbiosis occurs in IMNM patients and is correlated with systemic autoimmune features.
Assessment of pulmonary artery stiffness by multiparametric cardiac magnetic resonance-surrogate for right heart catheterization
Authors: Körperich Hermann , Eckstein Jan , Atito Medhat , Barth Peter , Laser Kai Thorsten , Burchert Wolfgang , Weber Oliver M. , Stehning Christian , Piran Misagh 
Published: August 2023

BackgroundCardiac magnetic resonance (CMR) imaging allows for multiparametric assessment of healthy pulmonary artery (PA) hemodynamics. Gender- and aging-associated PA stiffness and pressure alterations have remained clinically unestablished, however may demonstrate epidemiological differences in disease development. The aim of this study is to evaluate the role of CMR as a surrogate for catheter examinations by providing a comprehensive CMR assessment of sex- and age-related reference values for PA stiffness, flow, and pressure.Methods and ResultsPA hemodynamics were studied between gender and age groups (&gt;/&lt;50 years) using phase-contrast CMR. Corresponding correlation analyses were performed. 179 healthy volunteers with a median age of 32.6 years (range 11.3–68.2) were examined. Males demonstrated increased PA compliance (median [interquartile range] or mean ± standard deviation) (20.8 mm2/mmHg [16.6; 25.8] vs. 19.2 ± 7.1 mm2/mmHg; P &lt; 0.033), higher pulse wave velocity (2.00 m/s [1.35; 2.87] vs. 1.73 m/s [1.19; 2.34]; P = 0.018) and a reduced full width half maximum (FWHM) (219 ± 22 ms vs. 235 ± 23 ms; P &lt; 0.001) than females. Mean, systolic, diastolic PA pressure and pulmonary proportional pulse pressure were significantly elevated for males compared to females (P &lt; 0.001). Older subjects (&gt;50 years) exhibited reduced PA elasticity (41.7% [31.0; 52.9] vs. 66.4% [47.7; 83.0]; P &lt; 0.001), reduced PA compliance (15.4 mm2/mmHg [12.3; 20.7] vs. 21.3 ± 6.8 mm2/mmHg; P &lt; 0.001), higher pulse wave velocity (2.59 m/s [1.57; 3.59] vs. 1.76 m/s [1.24; 2.34]; P &lt; 0.001) and a reduced FWHM (218 ± 29 ms vs. 231 ± 21 ms; P &lt; 0.001) than younger subjects.ConclusionsVelocity-time profiles are dependent on age and gender. PA stiffness indices deteriorate with age. CMR has potential to serve as a surrogate for right heart catheterization.
Hunting paleoceanographic archives of ice sheet-ocean interaction in the northwestern Ross Sea, Antarctica
Authors: Kim Sookwan , De Santis Laura , Hong Jong Kuk , Colizza Ester , Kim Sunghan , Bergamasco Andrea , Lee Sang-Hoon , Kang Seung-Goo , Lee Min Kyung , Kim Hyoungjun , Choi Yeonjin , Geniram Andrea , Choi Hyoung Gyu , Lee Jae Il , Yoo Kyu-Cheul , Park Yongcheol 
Published: August 2023

The analysis of sedimentary deposits influenced by bottom currents in glaciated continental margins provides crucial insights into paleo-depositional and oceanographic conditions. These reconstructions enable the assessment of interactions between advance and retreat of grounded ice sheets and past ocean circulation patterns. However, questions regarding these interactions and their specific mechanisms remain largely unanswered due to a lack of data in this remote area. In this study, we conducted a comprehensive analysis by integrating marine geophysical data, surficial sediment cores, oceanographic measurements, and ocean circulation models. Our aim was to understand spatial and temporal variations in sedimentary and oceanographic conditions during the past glacial and interglacial periods in combination with the long-term stratigraphic evolution. By integrating and cross-referencing diverse datasets, we were able to infer how bottom-current-controlled deposits (i.e., contourites) developed along the western bathymetric high of the Central Basin in the northwestern Ross Sea margin, Antarctica. Contouritic deposits lying over and along the flanks of bathymetric highs were identified through their mound-shaped external geometry and acoustically stratified facies, characterized by reflectors pinching toward the moat. Acoustic facies and multi-beam backscatter results, in conjunction with sedimentary core data, revealed contrasting patterns. Bathymetric highs exhibited thin (&lt;10 m thick) coarser-grained sedimentary layers with higher backscatter, while the lower slope and rise displayed thick (&gt;10 m thick), finer-grained stratified sediments with lower backscatter. These findings indicate that seabed winnowing occurred by strong bottom current during past glacial periods as supported by sedimentological analysis. The pathways of the westward-deflected dense shelf water outflow and the westward-flowing along-slope current, as simulated by oceanographic models, explain the distinctive development of contourites influenced by bottom-current processes. Moreover, the large accumulations of sediment in the contourites, resulting from bathymetric barriers in the north of the Central Basin, may contribute to submarine slope failures.