bluuebunny/crossref_metadata_2025_split huggingface dataset:
Uji Efektivitas Infusa Rambut Jagung (Zea mays L) Sebagai Anti Diabetes Pada Mencit (Mus musculus) Yang Di Induksi Streptozotocin
Authors: Firmanto Gabriela Mega , Siharis Fatma Sari , Awaliyah Halid Nur Hatidjah 
Published: June 2023

Rambut jagung merupakan salah satu bagian dari jagung yang memiliki senyawa flavonoid yang bersifat sebagai antioksidan. Flavonoid dapat menurunkan kadar glukosa darah dengan kemampuannya sebagai zat anti oksidan. Flavonoid bersifat protektif terhadap kerusakan sel β sebagai penghasil insulin serta dapat meningkatkan sensitivitas insulin. Penelitian ini bertujuan untuk mengetahui infusa rambut jagung (Zea mays L) dapat memberikan aktivitas dan efektivitas sebagai anti diabetes pada mencit (Mus musculus) yang lebih optimal di banding dengan glibenklamid selaku kontrol positif. Penelitian ini adalah penelitian eksperimental laboratorium, sampel di buat dengan metode infusa dengan menggunakan pelarut air yang dipanaskan pada suhu 90˚C selama 15 menit. Pengujian efektivitas anti diabetes pada penelitian ini hewan uji dibagi menjadi 5 kelompok yaitu kelompok kontrol negatif (suspensi Na CMC 0.5%), kontrol positif (glibenklamid 0,013 mg), kelompok infusa rambut jagung 500 mg, kelompok infusa rambut jagung 1000 mg, dan kelompok infusa rambut jagung 2500 mg. Analisis data dilakukan dengan menggunakan One-Way ANOVA dan dilanjutkan dengan uji post hoc. Hasil penelitian menunjukan bahwa infusa rambut jagung (zea mays l) mempunyai efektivitas sebagai anti diabetes pada konsentrasi dosis 2500 mg dengan nilai signifikan (0,00<0,05) dan persen penurunan kadar gula darah sebesar 53% yang secara optimal sama dengan kontrol positif (glibenklamid 0,013 mg), atau dapat disimpilkan bahawa infusa rambut jagung ( zea mays l) dapat memberikan aktivitas dan efektivitas sebagai anti diabetes secara optimal sama dengan glibenklamid.
Hubungan Mutu Pelayanan Kefarmasian Terhadap Keberhasilan Berobat Pasien Diabetes Melitus (DM) Di RSUD Konawe Selatan
Authors: Yulianti Siska , Hamiru La Ode , Lolok Nikeherpianti , Baco Juliana 
Published: June 2023

Keberhasilan terapi DM terhadap pengobatan sangat berperan dalam kontrol glukosa darah pasien DM. Pelayanan kefarmasian di rumah sakit merupakan bagian yang tidak terpisahkan dari sistem pelayanan kesehatan Rumah Sakit yang berorientasi kepada pelayanan pasien, pelayanan sediaan farmasi, alat kesehatan, dan bahan medis habis pakai yang bermutu dan terjangkau bagi semua lapisan masyarakat termasuk pelayanan farmasi klinik Pemberian obat bertujuan untuk mencapai hasil yang dapat meningkatkan kualitas hidup pasien Oleh karena itu, dalam penggunaan obat diperlukan pertimbangan yang tepat agar penggunaannya efektif dan efisien.. Penelitian ini bertujuan Untuk mengetahui hubungan mutu pelayanan kefarmasian dengan kepatuhan berobat pasien diabetes melitus di Intalasi rawat inap RSUD Konawe Selatan. Jenis ini adalah penelitian kuantitatif dengan menggunakan desain penelitian cross sectional. Jumlah populasi penelitian ini adalah 89 orang, Metode yang digunakan yaitu total sampling. Metode analisis menggunakan distribusi frekuensi, Chi squere dan Koefisien Ph.i Hasil penelitian ada hubungan antara keadaan fisik dengan kepatuhan berobat pasien Diabetes Melitus di Instalasi rawat inap RSUD Konawe Selatan. Ada hubungan antara ketanggapan dengan kepatuhan berobat pasien Diabetes Melitus di Instalasi rawat inap RSUD Konawe Selatan. Ada hubungan antara kehandalan dengan kepatuhan berobat pasien Diabetes Melitus di Instalasi rawat inap RSUD Konawe Selatan. Ada hubungan antara jaminan dengan kepatuhan berobat pasien Diabetes Melitus di Instalasi rawat inap RSUD Konawe Selatan. Ada hubungan antara peduli dengan kepatuhan berobat pasien Diabetes Melitus di Instalasi rawat inap RSUD Konawe Selatan.
Evaluasi Rasionalitas Penggunaan Obat Hipertensi di Puskesmas Langara Konawe Kepulauan Sulawesi Tenggara Tahun 2020
Authors: Andriani Desi , Ali Hanafi La Ode , Pusmarani Jastria 
Published: June 2023

Hipertensi adalah suatu keadaan tekanan darah tinggi yang abnormal dan diukur paling tidak pada tiga kesempatan yang berbeda. Tekanan darah normal bervariasi sesuai usia, sehingga setiap diagnosis hipertensi harus bersifat spesifik usia. Penelitian ini bertujuan untuk mengetahui ketepatan penggunaan obat antihipertensi yang meliputi tepat obat, tepat dosis, tepat indikasi dan tepat frekuensi pemberian obat pada pasien hipertensi yang berobat pada bulan Januari sampai Desember 2019 di Puskesmas Langara Konawe Kepulauan Sulawesi Tenggara dengan jumlah sampel 82 pasien. Jenis penelitian ini menggunakan metode deskriptif kuantitatif dengan teknik pengambilan data secara retrospektif berdasarkan dengan melihat resep dan buku registrasi rekam medik pasien. Evaluasi yang dilakukan ini membandingkan data yang diteliti dengan literature. Hasil penelitian menunjukkan analisis rasionalitas penggunaan obat antihipertensi di Pusekesmas Langara Konawe Kepulauan Sulawesi Tenggaraberdasarkan tepat obat mencapai 100%, tepat indikasi mencapai 100% untuk hipertensi stage 1 dan 85,7% untuk hipertensi stage 2, tepat dosis mencapai 100% dan tepat frekuensi pemberian mencapai 100%.
The Value Co-creation Service Mode Design of Online Technology Market
Authors: Xu Wenling , Wang Yun 
Published: June 2023

Technology is now the primary force behind economic growth and increased productivity in the era of the digital economy. The online technology market is the main platform for technology trading and is a new strategic industry. The service mode of the online technology market can improve user service and enable the co-creation of user value. At first, a thorough review of the literature is performed to investigate the online technology market, service design and mode, value co-creation theory and its application. Second, it classifies various online technology market types and the service modes of various platforms using a comparative analytical approach, and it draws conclusions about how these service modes will develop. Eventually, the design subjects, design factors and processes, and design forms in the technology transaction process of the online technology market are studied, the service mode design model of the online technology market is developed, and the design results are generated. This essay encourages the growth of service design for the online technology market by offering useful concepts and workable recommendations for the service mode.
The application of brand Narrative Theory to brand building in Creative cities: A case study of Nanjing
Authors: Yang Xu , Sun Xin , Xie Dandan 
Published: June 2023

From the perspective of brand narrative theory, this study takes the city brand of Nanjing as an example to conduct a survey of online information, comprehensive use of big data collection, social network analysis and other methods to explore the internal characteristics of the brand of Nanjing City of Literature, build a visual knowledge map of big data, and clarify the overall narrative characteristics of the brand building achievements of Nanjing City of Literature at current period. In order to summarize and analyze the direction of the brand narrative strategy of Nanjing City of Literature, and finally put forward the strategy of applying narrative strategy to the construction of local city cultural brand, which provides a reference for basic research and decision-making basis for relevant policy formulation and research.
SOME ASPECTS OF COMPENSATION FOR HARM TO LIFE AND HEALTH IN PLACES OF DEPRIVATION OF LIBERTY
Authors: Кулемина П.А. , Неверов В.И. 
Published: June 2023

В динамично развивающемся мире, где существует множество различных угроз, наиболее развитые правовые системы понимают и справедливо провозглашают приоритет защиты нематериальных благ, присущих личности. Социальная ценность личных прав и нематериальных благ, принадлежащих человеку, является индикатором общей зрелости цивилизации и значимости для нее отдельного индивида.
In a dynamically developing world, where there are many different threats, the most developed legal systems understand and rightly proclaim the priority of protecting the intangible benefits inherent in the individual. The social value of personal rights and intangible benefits belonging to a person is manifested as an indicator of the general maturity of civilization and the importance of an individual for it.
ON THE ISSUE OF CONTROL OVER BUSINESS ENTITIES
Authors: Родионов Л.А. , Таренкова О.А. 
Published: June 2023

Данная статья посвящена контрольно-надзорной деятельности государства, в частности реформе по уменьшению административной нагрузки на субъектов предпринимательской деятельности. Обращается внимание на минимизацию взаимодействия контрольных органов и субъектов предпринимательской деятельности как подконтрольных субъектов, что прослеживается в Федеральном законе «О государственном контроле (надзоре) и муниципальном контроле в Российской Федерации».
This article is devoted to the control and supervisory activities of the state and, in particular the reform to reduce the administrative burden on business entities. Attention is drawn to minimizing the interaction of control bodies and business entities as controlled entities, which can be traced in the Federal Law “On State Control (Supervision) and Municipal Control in the Russian Federation”.
Encapsulated polycaprolactone with triazole derivatives and selenium nanoparticles as promising antiproliferative and anticancer agents
Authors: Abdelhamid Ahmed El-Sayed , El-Sayed Ahmed , Swelam Samira A. , Soliman Abdelmohsen M. , Khalil Ahmed M. 
Published: June 2023

Background and purpose: Polycaprolactone nanocapsules incorporated with triazole derivatives in the presence and absence of selenium nanoparticles were prepared and evaluated as antiproli­ferative and anticancer agents. Polycaprolactone nanoparticles were prepared using the emulsion technique. Experimental approach: The prepared capsules were characterized using FT-IR, TEM and DLS measurements. The synthesized triazo­lopyrimidine derivative in the presence and absence of selenium nanoparticles encap­sulated in polycaprolactone was tested for its in vitro antiproli­ferative efficiency towards human breast cancer cell line (MCF7) and murine fibroblast normal cell line (BALB/3T3) in comparison to doxorubicin as a standard anticancer drug. Key results: The results indicated that encapsulated polycapro­lactone with selenium nanoparticles (SeNPs) and triazole-SeNPs were the most potent samples against the tested breast cancer cell line (MCF7). On the other hand, all compounds showed weak or moderate activities towards the tested murine fibroblast normal cell line (BALB/3T3). Conclusion: As the safety index (SI) was higher than 1.0, it expanded the way for newly synthesized compounds to express antiproliferative efficacy against tumour cells. Hence, these compounds may be considered promising ones. However, they should be examined through further in-vivo and pharmacokinetic studies.
Ketaatan Kepada Pemerintah Dalam Perspektif Perjanjian Baru
Authors: Zebua Kasieli , Gani Mario 
Published: June 2023

In the New Testament, there is quite a lot of advice for Christians to submit and obey the government. Advice like this is of course still relevant today, and it is important to be explored as a guideline for Christians to be right towards the government, both towards the right government and the cruel government. But to what extent and within what limits should Christians obey the government? This study uses a literature review method with an emphasis on theological studies that aims to find truths from biblical investigations about Christian obedience to the government. From the results of the research found the teachings of the Bible about the right attitude of Christians towards the government as God's servants ordained by God. And also the limitation of obedience when the government is not in line with God's will and even against God's purpose. So that this becomes the basis for today's Christians to respond to various government regulations and policies in accordance with the truth of God's Word. Also as a basis that reflects a life that is bright and exemplary as a follower of Christ in the midst of society.

Abstrak
Di dalam Alkitab Perjanjian Baru cukup banyak nasihat agar orang Kristen tunduk dan taat kepada pemerintah. Nasihat semacam ini tentunya tetap relevan zaman sekarang, dan penting untuk didalami menjadi pedoman bagi orang Kristen untuk bersikap benar terhadap pemerintah, baik kepada pemerintah yang benar maupun pemerintah yang kejam. Namun sejauh mana dan dalam batas-batas apa orang Kristen harus taat kepada pemerintah? Penelitian ini menggunakan metode kajian kepustakaan dengan penekatan kajian teologis yang bertujuan untuk menemukan kebenaran-kebenaran dari penyelidikan biblikal tentang ketaatan orang Kristen kepada pemerintah. Dari hasil penelitian ditemukan ajaran Alkitab tentang sikap yang benar dari orang Kristen terhadap pemerintah sebagai hamba Allah yang ditetapkan Allah. Dan juga batasan ketaatan ketika pemerintah tidak sejalan dengan kehendak Allah bahkan menentang tujuan Allah. Sehingga hal ini menjadi dasar bagi orang Kristen masa kini menyikapi berbagai peraturan dan kebijakan pemerintah sesuai dengan kebenaran Firman Tuhan. Juga sebagai dasar yang mencerminkan kehidupan yang menjadi terang dan teladan sebagai pengikut Kristus di tengah-tengah masyarakat.
Resenha: PEDROSO, C.C.A; DOMINGUES, J.; FUSARI, J. C; GOMES, M. de O.; PIMENTA, S. G.; PINTO, V. de A.; Belletati, V. C. F. (Orgs.). Curso de Pedagogia. Inovações na formação de professores polivalentes. 1 ed. São Paulo: Cortez, 2019, 200p.
Authors: Saba Marly 
Published: June 2023

O livro Curso de Pedagogia. Inovações na formação de professores polivalentes (São Paulo, Editora Cortez, 2019), compilado por professores pesquisadores do Grupo de Estudos e Pesquisas sobre Formação de Educadores (Gepefe), vinculado ao Programa de Pós-Graduação da Faculdade de Educação da Universidade de São Paulo (FEUSP-SP) traz resultados da pesquisa coletiva sobre formação de professores polivalentes no Curso de Pedagogia. Com vistas ao debate que envolve questões complexas, entre os quais os conceitos de inovação e de professor polivalente, os autores trazem reflexões sobre o cenário educacional e os embates das políticas educacionais na formação de professores, além de concepções teóricas que apontam alternativas para um avanço teórico e prático na formação de professores para a educação básica, entre elas, a formação humana, a pesquisa como princípio formativo e a interdisciplinaridade.
Palavras-chave: Educação. Curso de Pedagogia. Professor Polivalente. Inovação
Escola Sem Partido (ESP): indicativos de representações sociais de professores
Authors: Machado Laeda Bezerra , Mendes Mayara Correa da Silva 
Published: June 2023

O artigo tem, como objetivo, identificar as representações sociais construídas por docentes do Ensino Médio a respeito do movimento “Escola Sem Partido” (ESP). A Teoria das Representações Sociais foi tomada como referencial para a pesquisa. Participaram do estudo 15 docentes de Ensino Médio de Recife-PE e Região Metropolitana. Os procedimentos de coleta utilizados foram questionário e entrevista. O material foi processado pelo software IRAMUTEQ, que gerou uma nuvem de palavras e uma figura (análise de similitude). Os resultados apontam como elementos de representação social do ESP: o professor como figura central dos ataques propostos pelo movimento, posição de neutralidade dos docentes e a falta de informações sobre o ESP. Sugere-se que sejam tomadas iniciativas, sobretudo, por parte dos sindicatos junto aos professores, a fim de oferecer maiores esclarecimentos sobre o ESP e suas implicações.
Palavras-chave: Escola sem partido. Representações Sociais. Professor.
Experiência, negociação e fé: redes que compõem o cotidiano com a escola
Authors: Castro Letícia Oliveira , Herneck Heloisa Raimunda , Monteiro Cíntia Castro 
Published: June 2023

Nesta pesquisa tivemos como objetivo viver a escola como experiência que transborda sensações, afetos, situações inusitadas e imprevistas. A pesquisa foi realizada em uma escola pública em Venda Nova do Imigrante, no estado do Espírito Santo, por meio da nossa imersão no cotidiano escolar de uma professora de Português e seus alunos/as. Como caminho metodológico, utilizamos a narrativa e diário de campo e foi por meio da enunciação dos sujeitos que acompanhamos a produção das redes de saberesfazeres escolares. Como resultados, evidenciamos às cenas de astúcias docentes e discentes que resistiam às normatividades impostas pelo sistema escolar. Em suma, seguimos as pistas para o entendimento das negociações realizadas entre os sujeitos praticantes da escola.
Palavras-chave: Experiência. Disciplinamento. Resistência e cotidiano escolar
A Matemática no Ensino Médio: o conhecimento construído na escola e as avaliações externas como indicador de proficiência
Authors: Bernardo Patrícia da Piedade 
Published: June 2023

Neste artigo discutem-se as dificuldades encontradas pelos docentes e discentes no processo ensino-aprendizagem em Matemática no Ensino Médio (EM), na perspectiva da educação com características de inovação social. Objetivou-se realizar uma discussão teórica sobre as práticas pedagógicas, o processo ensino-aprendizagem e as dificuldades em ensinar e aprender Matemática no EM. Para alinhamento das ideias buscou-se a análise teórica e conceitual sobre a importância da Matemática, o espaço sala de aula e o papel do professor, a construção do conhecimento matemático no EM, o Sistema de Avaliação da Educação Básica (SAEB), as avaliações externas como indicador de proficiência em Matemática, as práticas pedagógicas e o processo ensino-aprendizagem em uma perspectiva inovadora. A partir das leituras realizadas, constatou-se que são diversos os fatores que dificultam o processo de ensinar e aprender Matemática na rede pública, especialmente, no Ensino Médio.
Palavras-chave: Práticas Pedagógicas em Matemática. Processo Ensino-aprendizagem. Ensino Médio. Proficiência. Inovação Social.
Internet Based Text Material: Its Impact to Students’ Reading Comprehension on Skimming and Scanning for Information to the Seventh Grade of SMP Wahidiyah
Authors: Putri Novitasari  
Published: June 2023

ABSTRACT

The objective of this study intended to find out whether there is significance influence of internet based text material to the students’ reading comprehension on scanning and skimming for information to the Seventh Grade of SMP Wahidiyah. In this research text was specified on descriptive text. Descriptive quantitative research was implemented as the research design. The sample of this research was students from 7A at SMP Wahidiyah which consist of 41 students. They were given a pre-test and post-test. The result showed that the mean score before students taught using internet based text material was 68,41 and the score after being taught using internet based text was 93,4. The result of t-score was 17,59 and the t-table was 1,68 at the level of significance was 0,05. Furthermore, from the data it can be seen that the students’ score and their mean score was increased. Related to the hypothesis and the data analization, it can be concluded that the alternative hypothesis (Ha) was accepted and the null hypothesis (H0)was rejected. It means that there was significanct influence of internet based text material to the students’ reading comprehension on scanning and skimming for information to the Seventh Grade of SMP Wahidiyah.

Keywords: internet based text, reading comprehension, scanning, skimming
Value of Time Drives Operational Costs of Road Freight Transport Operators (RFTO): A Case Study in Zimbabwe
Authors: Mujakachi Tapiwa Christopher , Tukuta Marian , Tsvere Maria 
Published: June 2023

From a business viewpoint, freight transportation is a necessity in the globalized world we live in. Companies are becoming more dependent on goods from various different locations worldwide and the demand for coordinated transportation is increasing. The aim of the study was to ascertain if Road Freight Transport Sector in Zimbabwe respected the value of time aspect in their operations. Value of time is a sound principle that strategically propels the business into the future. Literature highly recommends the value of time concept for business success as a key to customer satisfaction and an international best practice. This was a quantitative study of the road freight transport sector across Zimbabwe with a population of 1256 registered companies and a randomly picked sample size of 384. A total of 384 questionnaires were distributed and 291 were retrieved, giving a response rate of 75.6%. The study findings indicate that value positively influence firm competitiveness. This implies that travel time and reliability influences company’s reputation, profitability, customer satisfaction and market share. Several empirical studies have reached similar findings (Chi, King-lok, Steven, 2012; Song et al, Gitae, 2017) that value of time has positive impact on firm competitiveness. Study also found that all the registered companies that took part in the research confirmed that the value of time phenomenon was alien to their business practices as they worked on assumptions. They also indicated a loss of business due to customer complaints. The study recommends policy formulation for companies that emphasizes standard operating procedures and good time management for firms to be competitive. The study results and interpretation show that value of time positively influences firm competitiveness. Results imply that if firms in the road freight sector conduct regulars servicing of their fleet, train their employees, plan routes properly, respond to their customers and manage risks there can remain competitive.
Sintesis Nanoemulsi dari Ekstrak Kulit Manggis dengan Metode Energi Tinggi
Authors: Rizki Tri , Yasni Sedarnawati , Muhandri Tjahja , Yuliani Sri 
Published: June 2023

Mangosteen (Garcinia mangostana L.) has become the main agricultural products contributing to the largest annual foreign exchange from the fruit category. Mangosteen rind contains xanthone compounds as a source of antioxidants, with α-mangostin and γ-mangostin, as the main components which are used as traditional and modern ingredients to treat various diseases. However, mangosteen rind extract has low bioavailability thus resulting in low effectiveness in the application. This study aimed to find the ideal formulation for producing the extract and nanoemulsion of mangosteen peel. The research carried out in two stages: extraction of mangosteen peel and production of nanoemulsion. Ethanol 70% was the best for mangosteen rind extraction, with a percentage yield of 40.96±0.51%, antioxidant activity of 5708.33±159.57 µg AEAC/mL sample, and total xanthones of 373.84±6.49 µg/mL sample. The use of Tween 20 at nanoemulsion production gave the best test results, with particle size of 10.58±1.25 nm, polydispersity index 0.27±0.03, zeta potential -2.34±0.46 mV, and total xanthones 35,28±0,04 µg/mL sample.