bluuebunny/crossref_metadata_2025_split huggingface dataset:
Palyatif Bakım Hastalarının Tamamlayıcı ve Bütünleşik Terapileri Ağrı Yönetiminde Kullanım Durumları
Authors: AKÇA Nazan , YALDIRAN Demet , DEMİRKOL SAKAR Derya 
Published: August 2023

Giriş: Palyatif bakım hastalarında ağrı semptomu ile baş edebilmek zor bir durumdur. Tamamlayıcı ve bütünleşik uygulamalar ağrı semptomunu yönetmede tedaviye ek olarak kullanılabilen kanıta dayalı uygulamalardır. Bu çalışmanın amacı, palyatif bakım hastalarının ağrı özelliklerinin yanı sıra ağrıyı yönetmek için kullanılan tamamlayıcı ve bütünleşik terapileri değerlendirmektir.
Yöntem: Tanımlayıcı nitelikte olan bu çalışma, bir hastanenin palyatif bakım kliniğine başvuran 102 hastadan dahil edilme kriterlerine uyan 77 hasta ile gerçekleştirilmiştir. Araştırmanın verileri; Hasta Bilgi Formu, Visual Analog Skala, Tamamlayıcı ve Bütünleşik Terapi Kullanım Durumları Anketi kullanılarak yüz yüze görüşme ile toplanmıştır. Veriler toplanmadan önce etik kurul onayı ve kurum izni alınmıştır. Veriler tanımlayıcı istatistikler kullanılarak değerlendirilmiştir. p
video interactivo: Recurso Innovador generador de Transversalidad en la Enseñanza
Authors: Martínez Cortés Jorge , Guevara Bazán Isaí Alí , Estrada Esquivel Ana Luisa , Encino Arambula Rosalva 
Published: August 2023

El problema de investigación es la dificultad de los profesores y estudiantes para incorporar la tecnología en el proceso de enseñanza y aprendizaje. El objetivo de esta investigación cuantitativo descriptivo de intervención es conocer el impacto que tiene la propuesta didáctica de presentar que el uso del video tiene otro alcance didáctico como la práctica de alguna temática específica para complementar el contenido a trabajar dentro o fuera del salón de clases a través de una plataforma educativa. La metodología consistió en una intervención en dos grupos, se aplicó una encuesta después de la intervención para evaluar la accesibilidad y entorno de la plataforma. Encontrando que la propuesta resultó motivante y fortalece la enseñanza y el aprendizaje; concluyendo la importancia de generar ambientes virtuales y herramientas digitales a pesar de la limitación de condiciones técnicas por parte de la institución
Validación de instrumento para medir experiencias de aprendizaje durante COVID-19
Authors: Trujillo Gómez Luz Arely , Carranza Alcántar María del Rocío , Cedillo Monzón Rubén Ulises , Ponce Rojo Antonio 
Published: August 2023

La pandemia por COVID-19 implicó retos para modificar la operatividad de las clases. El alumnado experimentó diversas prácticas para continuar su formación en los niveles que cursa. Así, el objetivo del presente es exponer la validación de un instrumento diseñado para conocer experiencias de aprendizaje virtual en estudiantes de múltiples grados. El estudio es cuantitativo, de alcance descriptivo-transversal. Los resultados muestran la fiabilidad del instrumento bajo análisis factorial y alpha de cronbach. Se exponen escenarios a los que tienen acceso los alumnos para continuar sus estudios. El cuestionario puede aplicarse en otros contextos para conocer impactos que la pandemia implica.
Propaganda política eleitoral na internet
Authors: Batista Letticia Antonia , Almeida Júnior Fernando Frederico 
Published: August 2023

O trabalho busca averiguar se a internet é um instrumento apto à realização da propaganda eleitoral e analisar qual o tratamento legislativo e jurídico a respeito, demonstrando a interferência positiva e negativa diante do pleito. Objetiva-se demonstrar a importância da internet e das redes sociais para a propagação da propaganda eleitoral. Especificamente, pretende apresentar as normatizações a respeito; demonstrar o uso e a realização da propaganda eleitoral na internet pelos candidatos e partidos e o acesso e engajamento do eleitorado nos meios virtuais e, verificar, as decisões e entendimentos acerca das propagandas irregulares e do fenômeno que pode comprometer a lisura do pleito eleitoral e influenciar de maneira errônea o eleitorado em detrimento de determinado candidato.
SOBRE A NORMATIZAÇÃO DO CORPO MODERNO UMA BREVE ANÁLISE DA PATOLOGIZAÇÃO DA TRANSEXUALIDADE E DE INSCRIÇÕES CORPORAIS
Authors: Latini Pfeil Bruno , Latini Pfeil Cello 
Published: August 2023

Almejamos, no presente artigo, compreender como ocorre a inferiorização de certas inscrições corporais, em detrimento da naturalização de outras, e em relação a marcadores de gênero, raça e normatividade. Partimos da hipótese de que o saber moderno institucionalizado produz patologização e criminalização de certas inscrições corporais, e tomamos como ferramenta de análise as modificações corporais realizadas por pessoas trans. Argumentamos que, ao afrontarmos a corponormatividade, ao demonstrarmos autonomia corporal em relação a nossos desejos e identidades, a retroativa institucional é violenta. Para tanto, nosso referencial teórico é anarquista e decolonial.
ALGUMAS REFLEXÕES SOBE O COVID-19 E A RECOLONIZAÇÃO DO CORPO NACIONAL
Authors: Basatti Ana Paula 
Published: August 2023

Este ensaio se propõe pensar como a epidemia do COVID-19 está colocando em jogo a manutenção da reprodução do corpo nacional. Para legitimar o que o Estado biopoliticamente define como o corpo “valido”, Bolsonaro e sua equipe buscam o controle da narrativa promovendo regimes de “verdade” sobre o COVID-19. Uma das estratégias usadas pelo Estado vem sendo a reinvenção de “imaginários morais”, como já era comum mesmo antes das eleições de 2018, quando Bolsonaro e sua equipe recriam imaginários éticos, reterritorializados e atemporais. Um deles é sobre seu “corpo de atleta” que busca reconstruir narrativas sobre a vida biológica nacional “superior” forjada desde a década de 70. A disputa pelo domínio dos imaginários conflagra um dos desafios que as esquerdas estão tendo, de recolonizar a narrativa política com o espaço simbólico da cidade vazia, numa sociedade fortemente marcada pelo teor do espetáculo.
PERILAKU FINANSIAL PERANGKAT DESA DALAM PERENCANAAN PENSIUN
Authors: Firmadhani Citra 
Published: August 2023

ABSTRAK

Perangkat desa merupakan aparat yang memberikan pelayanan kepada masyarakat di tingkat desa. Namun kedudukan, kemampuan dan kesejahteraan perangkat desa hingga saat ini masih terus dikaji khususnya saat memasuki masa pensiun. Penelitian ini bertujuan untuk menganalisis perilaku finanial perangkat desa dalam proses perencanaan pensiun. Metode yang digunakan dalam penelitian ini adalah metode penelitian kualitatif dengan pendekatan deskriptif yaitu dengan menggambarkan peristiwa yang terjadi di lapangan. Data dikumpulkan melalui teknik wawancara, dokumentasi dan observasi. Perilaku finansial perangkat desa dianalisis melalui 4 aspek yaitu jumlah tabungan, berinvestasi dalam aset berisiko, tabungan pensiun dan manajemen hutang. Hasil penelitian menemukan bahwa perangkat desa belum merencanakan pensiun dengan baik. Hal tersebut disebabkan karena kurangnya edukasi tentang perencanaan keuangan yang membentuk perilaku finansial perangkat desa.

Kata Kunci : Perilaku Finansial, Perangkat Desa, Perencanaan Pensiun
Un loup dans la bergerie – Pourquoi les animaux domestiques ne sont pas tous protégés de la même manière
Authors: Ménard Daphnée B 
Published: August 2023

La Loi visant l’amélioration de la situation juridique de l’animal, adoptée à l’unanimité en 2015, constitue la dernière évolution législative majeure en droit animalier québécois. Cette loi modifie le statut juridique de l’animal, le faisant passer de bien à être sensible, et instaure un cadre juridique plus strict en ce qui concerne le bien-être et la sécurité de l’animal domestique. Malgré ces changements, la sensibilité et les impératifs biologiques de nombreux animaux sont toujours niés, notamment à la ferme, créant des situations toutes plus absurdes les unes que les autres : un cochon de compagnie doit être protégé de la chaleur excessive sous peine prévue à la loi, tandis que des cochons d’élevage meurent de chaleur, littéralement, lors de canicules. Comment expliquer un tel décalage? Pourquoi les animaux sensibles ne sont-ils pas tous protégés de la même manière? Selon la théorie de la convergence des intérêts, un changement social en faveur d’un groupe minoritaire ne peut avoir lieu que lorsque les intérêts de la majorité et ceux de la minorité « convergent » pareillement vers ce changement. La convergence des intérêts est une explication plausible de ce décalage. Cet article s’intéresse notamment au contexte d’adoption de la Loi visant l’amélioration de la situation juridique de l’animal. L’analyse du contenu des travaux parlementaires permet de constater qu’en plus d’un certain souci pour l’animal, des raisons économiques et sociales sont à la source de la nouvelle législation et que des intérêts économiques en expliquent les limites, confirmant ainsi la présence du phénomène de la convergence des intérêts lors de son élaboration.
Sclerostin small-molecule inhibitors promote osteogenesis by activating canonical Wnt and BMP pathways
Authors: Sangadala Sreedhara , Kim Chi Heon , Fernandes Lorenzo M , Makkar Pooja , Beck George R , Boden Scott D , Drissi Hicham , Presciutti Steven M 
Published: August 2023

Background:The clinical healing environment after a posterior spinal arthrodesis surgery is one of the most clinically challenging bone-healing environments across all orthopedic interventions due to the absence of a contained space and the need to form de novo bone. Our group has previously reported that sclerostin in expressed locally at high levels throughout a developing spinal fusion. However, the role of sclerostin in controlling bone fusion remains to be established.Methods:We computationally identified two FDA-approved drugs, as well as a single novel small-molecule drug, for their ability to disrupt the interaction between sclerostin and its receptor, LRP5/6. The drugs were tested in several in vitro biochemical assays using murine MC3T3 and MSCs, assessing their ability to (1) enhance canonical Wnt signaling, (2) promote the accumulation of the active (non-phosphorylated) form of β-catenin, and (3) enhance the intensity and signaling duration of BMP signaling. These drugs were then tested subcutaneously in rats as standalone osteoinductive agents on plain collagen sponges. Finally, the top drug candidates (called VA1 and C07) were tested in a rabbit posterolateral spine fusion model for their ability to achieve a successful fusion at 6 wk.Results:We show that by controlling GSK3b phosphorylation our three small-molecule inhibitors (SMIs) simultaneously enhance canonical Wnt signaling and potentiate canonical BMP signaling intensity and duration. We also demonstrate that the SMIs produce dose-dependent ectopic mineralization in vivo in rats as well as significantly increase posterolateral spine fusion rates in rabbits in vivo, both as standalone osteogenic drugs and in combination with autologous iliac crest bone graft.Conclusions:Few if any osteogenic small molecules possess the osteoinductive potency of BMP itself – that is, the ability to form de novo ectopic bone as a standalone agent. Herein, we describe two such SMIs that have this unique ability and were shown to induce de novo bone in a stringent in vivo environment. These SMIs may have the potential to be used in novel, cost-effective bone graft substitutes for either achieving spinal fusion or in the healing of critical-sized fracture defects.Funding:This work was supported by a Veteran Affairs Career Development Award (IK2-BX003845).
Effects of smoking on genome-wide DNA methylation profiles: A study of discordant and concordant monozygotic twin pairs
Authors: van Dongen Jenny , Willemsen Gonneke ,   BIOS Consortium, de Geus Eco JC , Boomsma Dorret I , Neale Michael C 
Published: August 2023

Background:Smoking-associated DNA methylation levels identified through epigenome-wide association studies (EWASs) are generally ascribed to smoking-reactive mechanisms, but the contribution of a shared genetic predisposition to smoking and DNA methylation levels is typically not accounted for.Methods:We exploited a strong within-family design, that is, the discordant monozygotic twin design, to study reactiveness of DNA methylation in blood cells to smoking and reversibility of methylation patterns upon quitting smoking. Illumina HumanMethylation450 BeadChip data were available for 769 monozygotic twin pairs (mean age = 36 years, range = 18–78, 70% female), including pairs discordant or concordant for current or former smoking.Results:In pairs discordant for current smoking, 13 differentially methylated CpGs were found between current smoking twins and their genetically identical co-twin who never smoked. Top sites include multiple CpGs in CACNA1D and GNG12, which encode subunits of a calcium voltage-gated channel and G protein, respectively. These proteins interact with the nicotinic acetylcholine receptor, suggesting that methylation levels at these CpGs might be reactive to nicotine exposure. All 13 CpGs have been previously associated with smoking in unrelated individuals and data from monozygotic pairs discordant for former smoking indicated that methylation patterns are to a large extent reversible upon smoking cessation. We further showed that differences in smoking level exposure for monozygotic twins who are both current smokers but differ in the number of cigarettes they smoke are reflected in their DNA methylation profiles.Conclusions:In conclusion, by analysing data from monozygotic twins, we robustly demonstrate that DNA methylation level in human blood cells is reactive to cigarette smoking.Funding:We acknowledge funding from the National Institute on Drug Abuse grant DA049867, the Netherlands Organization for Scientific Research (NWO): Biobanking and Biomolecular Research Infrastructure (BBMRI-NL, NWO 184.033.111) and the BBRMI-NL-financed BIOS Consortium (NWO 184.021.007), NWO Large Scale infrastructures X-Omics (184.034.019), Genotype/phenotype database for behaviour genetic and genetic epidemiological studies (ZonMw Middelgroot 911-09-032); Netherlands Twin Registry Repository: researching the interplay between genome and environment (NWO-Groot 480-15-001/674); the Avera Institute, Sioux Falls (USA), and the National Institutes of Health (NIH R01 HD042157-01A1, MH081802, Grand Opportunity grants 1RC2 MH089951 and 1RC2 MH089995); epigenetic data were generated at the Human Genomics Facility (HuGe-F) at ErasmusMC Rotterdam. Cotinine assaying was sponsored by the Neuroscience Campus Amsterdam. DIB acknowledges the Royal Netherlands Academy of Science Professor Award (PAH/6635).
Understanding disruptions in cancer care to reduce increased cancer burden
Authors: Davis Kia L , Ackermann Nicole , Klesges Lisa M , Leahy Nora , Walsh-Bailey Callie , Humble Sarah , Drake Bettina , Sanders Thompson Vetta L 
Published: August 2023

Background:This study seeks to understand how and for whom COVID-19 disrupted cancer care to understand the potential for cancer health disparities across the cancer prevention and control continuum.Methods:In this cross-sectional study, participants age 30+residing in an 82-county region in Missouri and Illinois completed an online survey from June-August 2020. Descriptive statistics were calculated for all variables separately and by care disruption status. Logistic regression modeling was conducted to determine the correlates of care disruption.Results:Participants (N=680) reported 21% to 57% of cancer screening or treatment appointments were canceled/postponed from March 2020 through the end of 2020. Approximately 34% of residents stated they would need to know if their doctor’s office is taking the appropriate COVID-related safety precautions to return to care. Higher education (OR = 1.26, 95% CI:1.11–1.43), identifying as female (OR = 1.60, 95% CI:1.12–2.30), experiencing more discrimination in healthcare settings (OR = 1.40, 95% CI:1.13–1.72), and having scheduled a telehealth appointment (OR = 1.51, 95% CI:1.07–2.15) were associated with higher odds of care disruption. Factors associated with care disruption were not consistent across races. Higher odds of care disruption for White residents were associated with higher education, female identity, older age, and having scheduled a telehealth appointment, while higher odds of care disruption for Black residents were associated only with higher education.Conclusions:This study provides an understanding of the factors associated with cancer care disruption and what patients need to return to care. Results may inform outreach and engagement strategies to reduce delayed cancer screenings and encourage returning to cancer care.Funding:This study was supported by the National Cancer Institute’s Administrative Supplements for P30 Cancer Center Support Grants (P30CA091842-18S2 and P30CA091842-19S4). Kia L. Davis, Lisa Klesges, Sarah Humble, and Bettina Drake were supported by the National Cancer Institute’s P50CA244431 and Kia L. Davis was also supported by the Breast Cancer Research Foundation. Callie Walsh-Bailey was supported by NIMHD T37 MD014218. The content does not necessarily represent the official view of these funding agencies and is solely the responsibility of the authors.
The effects of trunk kinematics and EMG activity of wheelchair racing T54 athletes on wheelchair propulsion speeds
Authors: Guo Wei , Liu Qian , Huang Peng , Wang Dan , Shi Lin , Han Dong 
Published: August 2023

BackgroundThe purpose of this study is to examine the impact of trunk kinematic characteristics and trunk muscle electromyography (EMG) activity on propulsion speeds in wheelchair racing T54 athletes.MethodThe Vicon infrared high-speed 3D motion capture system was utilized to acquire kinematic data of the shoulders, elbows, wrists, and trunk from twelve T54 athletes at four different speeds (5.55 m/s, 6.94 m/s, 8.33 m/s, and personal maximum speed). Additionally, the Trigno Wireless EMG system was employed to collect synchronous surface electromyography (EMG) data from the rectus abdominis and erector spinae muscles. The kinematics and EMG data of the trunk were compared across various wheelchair propulsion speeds while also examining the correlation coefficient between wheelchair propulsion speeds and: (1) the range of motion of upper limb joints as well as the trunk; (2) the maximum angular velocities of the upper limbs joints as well as the trunk; and (3) rectus abdominis and erector spinae EMG activity. Two multiple linear stepwise regression models were utilized to examine the impact of variables that had been identified as significant through correlation coefficient tests (1) and (2) on propulsion speed, respectively.ResultsThere were significant differences in the range of motion (p<0.01) and angular velocity (p<0.01) of the athlete’s trunk between different propulsion speeds. The range of motion (p<0.01,r = 0.725) and angular speed (p<0.01,r = 0.882) of the trunk showed a stronger correlation with propulsion speed than did upper limb joint movements. The multiple linear stepwise regression model revealed that the standardizedβvalues of trunk motion range and angular velocity in athletes were greater than those of other independent variables in both models. In terms of the EMG variables, four of six variables from the rectus abdominis showed differences at different speeds (p<0.01), one of six variables from the erector spinae showed differences at different speeds (p<0.01). All six variables derived from the rectus abdominis exhibited a significant correlation with propulsion speed (p<0.05,r>0.3), while one variable derived from the erector spinae was found to be significantly correlated with propulsion speed (p<0.01,r = 0.551).ConclusionThe movement of the trunk plays a pivotal role in determining the propulsion speed of wheelchair racing T54 athletes. Athletes are advised to utilize trunk movements to enhance their wheelchair’s propulsion speed while also being mindful of the potential negative impact on sports performance resulting from excessive trunk elevation. The findings of this study indicate that it would be beneficial for wheelchair racing T54 athletes to incorporate trunk strength training into their overall strength training regimen, with a specific emphasis on enhancing the flexion and extension muscles of the trunk.
A review of the taxonomy and distribution of Australia’s endemic Calyptorhynchinae black cockatoos
Authors: Saunders Denis A , Pickup Geoffrey 
Published: August 2023

ABSTRACT
Our review of the taxonomy of Australia’s endemic Calyptorhynchinae black cockatoos based on morphology, ecology, biology, vocalisations, distributions, and genetic studies concluded that they constitute two genera; those with red subterminal tail bands in the genus Calyptorhynchus Desmarest, 1826 and those with white or yellow subterminal tail bands in the genus Zanda Mathews, 1913. We also concluded that the genus Calyptorhynchus is made up of six monotypic species: Northern Red-tailed Cockatoo C. banksii Latham, 1790; South-eastern Red-tailed Cockatoo C. graptogyne Schodde, Saunders and Homberger, 1988; Forest Red-tailed Cockatoo C. naso Gould, 1837; Inland Red-tailed Cockatoo C. samueli Mathews, 1917; Western Red-tailed Cockatoo C. escondidus Ewart, Joseph and Schodde, 2020; and Glossy Cockatoo C. lathami Temminck, 1807. Formerly, the five red-tailed taxa were regarded as subspecies and the Glossy Cockatoo consisted of three subspecies. In addition, we concluded that the genus Zanda is made up of five monotypic species: two with white subterminal tail bands, Baudin’s Cockatoo Z. baudinii Lear, 1832 and Carnaby’s Cockatoo Z. latirostris Carnaby, 1948; and three with yellow subterminal tail bands, Eastern Yellow-tailed Cockatoo Z. funerea Shaw, 1794, Western Yellow-tailed Cockatoo Z. whiteae Mathews, 1912, and Tasmanian Yellow-tailed Cockatoo Z. xanthanota Gould, 1838. Formerly, the three yellow-tailed taxa were regarded as subspecies. As all cockatoos with coloured subterminal tail bands are black, we recommend deleting the word black from their common names.
Effect of Nitrogen and Foliar Spray of Urea and Nano Urea on Growth and Yield of Rabi Maize (Zea mays L.)
Authors: Srivastava Avantika , Singh Rajesh 
Published: August 2023

A field experiment was conducted during Rabi 2022 at Crop Research Farm, Department of Agronomy, SHUATS, Prayagraj (U.P) to study the “Effect of nitrogen and foliar spray of urea and nano urea on growth and yield of rabi maize (Zea mays L.)”, to study treatments consisting of three levels of Nitrogen viz. 50% RDN, 75% RDN and 100% RDN and three foliar sprays of nano urea viz. 2000 ppm (2ml/L), 4000ppm (4ml/L), and foliar spray of urea viz., 20000 ppm (2%). The soil of experimental plot was sandy loam in texture, nearly neutral in soil reaction (pH 7.1), low in organic carbon (0.28 %), available N (225 kg/ha), available P (19.50 kg/ha) and available K (92 kg/ha). There were 10 treatments each being replicated thrice and laid out in Randomized Block Design. The results revealed that at 60 DAS, treatment combination 100% RDN + 4000 PPM (4ml/L) spray of Nano Urea recorded significantly higher Plant Height (108.10cm), Plant Dry weight (61.20 g), Crop Growth Rate (14.67 g/m2/day), number of cobs per plant (1.60), number of grains per cob (249.67), Seed index (23.55 g), Grain yield (6.41 t/ha), Stover yield (8.65 t/ha) and Harvest Index (42.58 %) as compared to other treatments.