bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fibrolipomatous Hamartoma of the Median Nerve: A Clinical Report of One Case and Review of the Literature
Authors: Xing Guojing , Shang Xiaojie , Huo Xiaoguang , Han Shiliang , Wang Yanzhen , Xu Wenzhe 
Published: January 2023

Background:The ultrasound imaging findings and clinical treatment procedure of a case of fibrolipomatous hamartoma of the median nerve are reported in this paper. The disease diagnosis was mainly dependent on magnetic resonance, and rarely described by ultrasound. This paper introduces the imaging manifestations of median neurofibromatoid hamartoma under ultrasound.Case Presentation:This case is a middle-aged female with pituitary adenoma. Fibrolipomatous hamartoma, as a rare benign fibrofatty tumor, is characterized by the slow proliferation of mature adipocytes and fibrous tissue around and inside the peripheral nerves, eventually leading to the fusiform enlargement of nerve fiber bundles.Disscussion:This paper discusses the value and application of color doppler ultrasound in the diagnosis of FLH to provide a reference for the clinical diagnosis and treatment of this disease in the future and reviews the literature on this disease.Conclusion:Because fibrolipomatous hamartoma is very rare, it is very important to improve the understanding and diagnosis of this disease.
Assessment of Circulating CCR6 Level in Acute Myocardial Infarction
and its Association with Disease Severity
Authors: Abdelrahman Amira Mohamed Noureldin , Mohamed Amal Elmahdy , Bendary Ahmed Mahmoud , Sedki Amira Adel , El-Shimi Ola Samir 
Published: January 2023

Background:
Background: Acute myocardial infarction (AMI) pathophysiology is mediated by systemic, intraplaque myocardial inflammatory processes that occur mainly due to coronary artery thrombosis in an atherosclerotic plaque area. The G-protein-coupled chemokine receptor (Ccr6) is displayed on the surface of many types of leukocytes, that have been found in atherosclerotic plaques. It is a novel mediator of inflammation and immune response.

Objectives:
To determine CCR6 lymphocyte expression in AMI patients and its association with disease severity using the Gensini scoring system.

Methods:
25 AMI patients and 25 controls underwent flow cytometry to determine the percentage of circulating CCR6+ lymphocytes. To forecast AMI and determine how CCR6 expression relates to it, multivariate logistic regression analysis was used.

Results and Discussion:
There was a higher percentage of CCR6+ lymphocyte expression in AMI patients than in controls. In addition, CCR6 showed a significant positive correlation with the Gensini score (GS) in the AMI group then with the degree of coronary artery disease (CAD).

Conclusion:
The chemokine receptor Ccr6 is an independent biomarker for AMI and mayplay a role as a mediator of T lymphocyte recruitment, which is associated with coronary lesion destabilization.
Intranasal Delivery of Leuprolide Acetate Chitosan Nanoparticles for
Treatment of Alzheimer’s Disease
Authors: Pandya Tosha , Dharamsi Abhay 
Published: January 2023

Background:
Alzheimer’s is one of the primary causes and the most prevalent form of age-related dementia worldwide. There is an urgent surge to find an effective treatment for AD due to its social implications on society.

Aim:
Present research work aims to develop Chitosan nanoparticles of leuprolide acetate for the treatment of Alzheimer’s disease by delivery through the intranasal route.

Methods:
Chitosan nanoparticles encapsulating leuprolide acetate were prepared using the ionic ge-lation method and optimized using a central composite design. The optimized nanoparticles were evaluated by DSC study, TEM analysis, release study of the drug in vitro and ex vivo, histopatholo-gy study, and accelerated stability study, In vivo kinetic and dynamic study.

Results:
The optimized formulation exhibited particle size of 254.3 ± 10.7 nm, % EE of 85.6 ± 0.8
%, and zeta potential of +18.0 ± 0.2 mv. The release of drug from optimized nanoparticles in vitro
was in a sustained manner, with only 75.7 % drug released at 48 hours. Higher permeation of the
drug from nanoparticles (Papp =5.44 ± 0.34 x 104) was observed in the diffusion study ex vivo. Sheep
nasal toxicity and accelerated stability study proved the intranasal safety and stability of the developed
formulation. The in vivo drug uptake study indicated a greater brain drug concentration from
chitosan nanoparticles than from plain drug solution. The anti-Alzheimer potential was also evident
from behavioural studies and histopathology study of rat brain.

Conclusion:
Thus, the chitosan nanoparticulate formulation of leuprolide acetate was found to have great potential for Alzheimer’s disease management.
The Acceptability of Technology-Based Physical Activity Interventions in Postbariatric Surgery Women: Insights From Qualitative Analysis Using the Unified Theory of Acceptance and Use of Technology 2 Model
Authors: Thérouanne Pierre , Hayotte Meggy , Halgand Florent , d'Arripe-Longueville Fabienne 
Published: January 2023

Background
Bariatric surgery offers an opportunity for physical activity (PA) promotion due to patients’ increased ability to engage in PA. Technology-based PA interventions are promising tools for promoting PA to support patients in this key period. The Unified Theory of Acceptance and Use of Technology 2 (UTAUT2) model is a recognized theoretical model for examining technology acceptability. Although a previous study reported that 92% of women with obesity have high acceptability of at least one technology-based PA intervention, little is known about the factors that lead to different levels of acceptability between technologies and therefore the reasons for choosing a preferred intervention.

Objective
The purpose of this study was to (1) characterize the acceptability of 3 technology-based PA interventions (ie, telehealth, active video game, mobile app) in the context of bariatric surgery, and (2) explore patients’ preference motives. This study, using a qualitative design, examined the suitability of the UTAUT2 model in this specific context.

Methods
Participants (n=26) read written French descriptions of the technology-based PA interventions with illustrations and chose their preferred intervention. Semidirective interviews were conducted to explore the reasons for their choice of the preferred intervention, notably using the UTAUT2 framework. Data were analyzed based on inductive and deductive approaches.

Results
All participants who preferred a technology-based PA intervention (ie, active video game, n=10; mobile app, n=10; telehealth, n=6) expressed a behavioral intention to use it. In addition, some of them expressed a high behavioral intention to use another technology (ie, active video game, n=4; mobile app, n=1; telehealth, n=7). All the constructs of the UTAUT2 emerged during the qualitative interviews and were specified through subcategories. Additional constructs also emerged, especially other motivational factors.

Conclusions
This study showed that, in the context of technology-based PA interventions for postbariatric patients, the UTAUT2 is suitable, although additional motivational factors (which were not considered by the UTAUT2 model) should be considered.
DEVELOPMENT OF IMPROVED WEIGHED QUANTUM LION OPTIMIZATION FOR ALZHEIMER'S DISEASE WITH SMOOTH SUPPORT VECTOR MACHINE
Authors: Enumula Raveendra Reddy , K Rama Krishna Rao T 
Published: January 2023

Accurate diagnosis of Alzheimer’s disease(AD) and Mild Cognitive
Impairment(MCI) was identified on an early stage is essential in the
healthcare industry to stop degeneration. The Smooth Support Vector
Machine (SSVM) model, Principal Component Analysis (PCA), feature
extraction, and Magnetic Resonance Imaging (MRI) image preprocessing are
the components for the diagnosis of AD is proposed in this research at
early stage. To assist in the classifier’s training, we proposed a novel
Improved Weighed Quantum Lion Optimization (IWQLO). The SSVM parameters
are specifically proposed to be optimized using a new Switching delayed
Lion Optimization (SLO) algorithm.The IWQLO-SSVM approach was
effectively used to classify AD and MCI utilizing MRI scans of the
[Alzheimer’s disease Neuroimaging
Initiative](https://adni.loni.usc.edu/)(ADNI) database and Outcome and
Assessment Information Set (OASIS) database. For six example scenarios,
the classification accuracy of our proposed method is acceptable.
Testing show that the proposed approach improves the performance
measures such as accuracy, precision, specificity, sensitivity and
recallfor detecting the early stage AD diagnosis.
Heat conduction properties of thermally conductive interface materials with exfoliated graphite platelets
Authors: Chen Junjie 
Published: January 2023

The thermal interface material technologies used for electronic packages
encompass several classes of materials. However, there is still a need
for thermal interface materials and methods for making thermal interface
materials having improved thermal conductivity property by maximizing
the anisotropic benefit of exfoliated graphite platelets to the fullest
extent. The effect of filler volume fraction on the thermal resistivity
of the thermal contact and the thermal conductivity of the thermal
interface material is investigated for graphite platelets and carbon
black. The effect of pressure on the bond line thickness of the thermal
interface material is evaluated for smooth and rough surfaces. The
present study aims to provide a thermal interface material with aligned
graphite nanofibers in the thermal interface material to enhance the
material performance. Particular emphasis is placed upon the heat
conduction properties of thermally conductive interface materials with
exfoliated graphite platelets. The results indicate that polymeric
elastomer materials offer both high thermal performance and reasonable
gap filling capability to enable good contact between a semiconductor
component and a heat sink. Under mechanical pressure, the soft thermal
interface material conforms to the microscopic surface contours of the
adjacent solid surfaces and increases the microscopic area of contact
between the thermal solution surface and the silicon die surface and
therefore reduces the temperature drop across this contact. The heat
dissipating component should advantageously be relatively anisotropic,
as compared to a metal and exhibit a relatively high ratio of thermal
conductivity to weight. Thermal interface materials provide a limited
heat-conduction path and may include flexible heat-spreading materials
and one or more layers of soft thermal interface material. Reducing the
strain on the thermal interface material may reduce the potential for
pump-out and the associated increase in thermal resistance due to loss
of material from the interface. Thermal conductivity is driven primarily
by the nature of the filler, which is randomly and homogeneously
distributed throughout the matrix. Pump-out of the thermal interface
material results in increased thermal resistance due to loss of material
from the interface. The thermal interface material can migrate out of
the interface volume between the thermal conducting members and onto the
power input pads, resulting in excessive heating and part failure at the
power interconnect.
Keywords: Interface materials; Thermoplastic materials; Smooth
surfaces; Rough surfaces; Graphite platelets; Carbon black
DA PALESTINA AO MUNDO GRECO-ROMANO: OS DESAFIOS DO QUERIGMA
Authors: Silva Cleibson Américo da 
Published: January 2023

Na propagação do primeiro anúncio da fé cristã acerca da morte e ressurreição de Jesus Cristo - querigma - os primeiros discípulos encontraram imensos obstáculos, seja na Palestina, entre os conterrâneos de Jesus - ou mesmo entre os judeus da diáspora, dispersos no mundo helenístico - seja no mundo greco-romano, dominado pelo politeísmo, pelo culto religioso à figura do imperador, etc. Em relação aos primeiros, as maiores dificuldades partiam do fato de que os judeus não acreditaram na pessoa de Jesus, o nazareno, como sendo o “Māshyāḥ” profetizado e, em vista disso, tomaram uma postura de hostilidade à mensagem cristã. Já os segundos apresentavam resistências de ordem filosóficas, políticas, religiosas, éticas etc. Não obstante esses obstáculos, que renderam perseguição e morte a milhares de cristãos nos três primeiros séculos, o querigma foi anunciado e, paulatinamente, o cristianismo foi ocupando espaços e lançando as bases da civilização ocidental. Para percorrer esse trajeto do querigma cristão, não obstante os obstáculos, esse artigo foi dividido em três partes: a primeira apresenta a Palestina no século I e as relações entre judeus e cristãos; a segunda mostra o mundo greco-romano e a hostilidade ao querigma cristão; e, por fim, na terceira, o anúncio querigmático, apesar dos desafios ambientais, culturais, sociais, políticos e religiosos. Para tanto, foi usada uma metodologia bibliográfica de consulta a fontes primárias e secundárias, tanto da documentação histórica do cristianismo primitivo, quanto da literatura universal, com o objetivo de recompor o trajeto da mensagem cristã no mundo palestino e greco-romano. Palavras-chave:
Autônomo no Pensamento de Santo Tomás de Aquino
Authors: Bernardo Carlos Eduardo 
Published: January 2023

Neste breve escrito pretendemos refletir acerca de uma concepção atinente ao pensamento de Santo Tomás de Aquino, conforme exposta nas obras de Francis Schaeffer, mormente em seu livreto, A Morte da Razão[1]. Concepção essa que perpassa não apenas a trilogia à qual pertence esta obra, mas a todo o pensamento do autor em questão. Grosso modo, podemos dizer que Francis Schaeffer advoga encontrar na obra de Santo Tomás de Aquino, a ideia de uma autonomia da razão, mas não apenas isso, e sim uma autonomia da razão frente ao problema soteriológico.
Portanto, pretendemos averiguar se esta tese de Schaeffer se justifica ou não; para tanto, nos reportaremos não apenas à obra em questão, mas, sobretudo, aos escritos do próprio Santo Tomás de Aquino, que com certeza são abundantes na discussão sobre o status da razão, tanto no estado pré-queda, quanto no estado pós-queda, lembrando que este último é o mais relevante para a presente discussão.

[1]Escape From Reason (1968). Referir-se a esta obra como livreto, não deve ser entendido como um tom depreciativo, reporta-se apenas às suas pequenas proporções. Ainda assim, ela se reveste de importância fundamental para o pensamento cristão evangélico contemporâneo, junto ao livro O Deus que Intervém e ao título O Deus que se Revela (o primeiro e o último, respectivamente) compõe a trilogia que reflete, seriamente, em como nos âmbitos da literatura, da filosofia, da arte, da música, do teatro, do cinema e da televisão perdemos o rumo do conhecimento da verdade e mergulhamos em um abismo de irracionalidade e loucura que causou tanto a morte de Deus, quanto à morte do homem, em suma a morte da razão.
Study of agricultural finance policy information extraction based on ELECTRA-BiLSTM-CRF
Authors: Yang Airong , Xia Yong 
Published: January 2023

Abstract
As China’s agriculture has developed towards modern agriculture, agricultural finance has played a crucial role in promoting China’s rapid agricultural development. Due to the ineffective interpretation of policy support of agricultural finance, poor agricultural areas cannot benefit from the current policy. The purpose of this paper is to propose a model that combines the ELECTRA model with a bi-directional long- and short-term memory network, BiLSTM and conditional random field (CRF) for identifying agricultural finance policy information. The first step is to convert the plain text of agricultural finance policy into word vectors using ELECTRA’s pre-trained language model. By incorporating zigzag character substitution in the generator, the adaptability of the pre-training target to the annotation task on agricultural finance policy is improved. Next, the BiLSTM neural network is used to obtain the contextual abstract features of the serialised text. Finally, the global optimisation sequence decoding annotation is combined with the CRF to extract the structured agricultural finance policy information. The results indicate that the agricultural finance policy information extraction model is more effective than other models in capturing agricultural finance policy information and has excellent information extraction capabilities.
Wellness and Herbal Tourism Based on Local Wisdom as an Alternative to ‘New Normal’ Tourism
Authors: Widarini Paramita Sari Indah , Wijaya Mahendra , I N Albert Muhammad 
Published: January 2023

The government initiated a wellness and herbal tourism program, in collaboration with the Indonesian Ministry of Tourism and Creative Economy with the Ministry of Health. This tourism cluster is prioritized because it has high impact in improving health, cultural and economic field. This type of tourism is considered would provide fresh air in the New normal situations that require people to remain side by side with the Covid-19 pandemic situation. The author examines concretely the marketing communication strategy of tourism stakeholders in developing the program to see how the establishment of wellness and herbal tourism based on local wisdom as an alternative in tourism industry, especially in the New normal era. The author uses a marketing communication strategy with the SOSTAC + 3Ms model of marketing communication analysis, which was popularized by PR. Smith. This theory is considered could describe the integrated marketing communication science in the tourism industry. This research was conducted using a qualitative descriptive method, with an emphasis on the naturalistic inquiry paradigm. Direct interviews were conducted with competent primary sources who represent their fields. The results of this study describe the tourism stakeholders in Solo have been prepared for the development of the wellness and herbal tourism program, with a focus on the local wisdom of Solo's custom. However, the development and preparation of the wellness and herbal tourism program is deemed not optimal, because internal and external conditions are still hampered tourism business in the midst of the Covid-19 Pandemic.
<p>Impacto de la metodología e-Aprendizaje-Servicio en estudiantes universitarios durante la COVID-19 ¿favorece el trabajo en equipo y la innovación?</p>
Authors: Andrés Romero Magdalena Pilar , Fernández-Torres Mercedes , Salvador Ferrer Carmen 
Published: January 2023

Introducción. En este trabajo se pretende determinar si el e-Aprendizaje-Servicio, como metodología favorecedora del aprendizaje a partir de la acción y reflexión del alumnado sobre una necesidad social, produce consecuencias positivas en la competencia de trabajo en equipo orientada a la innovación y concretar qué áreas de ésta se ven favorecidas, así como el tipo de relación causal que podría existir entre éstas, la motivación de los estudiantes y el compromiso en el trabajo. Todas ellas competencias altamente demandadas en el ámbito laboral.
Método. Se plantea un diseño cuasi-experimental con 298 estudiantes pertenecientes al Grado en Turismo, Grado en Psicología y Grado en Maestro de Educación Infantil de la Universidad de Almería (España). Un grupo tuvo contacto con el e-ApS (198 estudiantes), y un segundo sin contacto (100 participantes). Como instrumentos se utilizan el Team Climate Inventory -TCI-14- (adaptado por Boada-Grau et al., 2011) y el Cuestionario de Aprendizaje y Servicio para entidades educativas para el alumnado [(CASee-A(U)] (Fernández-Torres et al., 2017).
Resultados. Las puntuaciones arrojan diferencias estadísticamente significativas entre ambos grupos en la variable apoyo a la innovación y se encuentran relaciones estadísticamente significativas y positivas entre todas las variables en el grupo experimental. Asímismo, los datos indican que la innovación, que se obtiene con la práctica del trabajo equipo con e-ApS, influye en el aumento de la motivación académica, lo cual a su vez repercute en el interés del estudiante para trabajar intentando lograr lo mejor, actuando ésta como variable mediadora entre ambas.
Discusión y conclusiones. Estos resultados evidencian la necesidad de que desde las Universidades comprometidas socialmente se impulsen acciones para consolidar estas prácticas en los Títulos Universitarios al favorecer el desarrollo de competencias transversales
المنهجُ النبويُ التربويّ وأثرهُ في إرساءِ قواعدِ جودةِ التربيةِ والتعليم
Authors: Muhammad Al-Hajj Wael Abdel Karim 
Published: January 2023

لقد بات إصلاح منظومة التربية و التعليم من القضايا الرئيسية التي تؤرق بال المسؤولين الحكوميين في شتى أنحاء العالم إيمانا منهم بأن تكوين الرأسمال البشري يعد الدعامة الأساسية لكل نهضة، والمنهج النبوي صالح لكل زمان ومكان لمرونه قواعده وشمولية مقاصده ، وشرف ونبل وسائله ؛لأنه يهدف الى بناء الأنسان روحياً ونفسياً وعقلياً وجسدياً ، وقد خطه الموضوع الموسوم: (المنهج النبوي التربوي وأثره في إرساء قواعد جودة التربية والتعليم ) المبحث الأول : التعريف بمفهوم المصطلحات الآتية( المنهج ، التربية ، الجودة).اما المبحث الثاني :1-التربية على القدوة الحسنة. 2-التربية بالحفاوة والترحيب وحسن الاستقبال . 3-التربية بالرفق والرحمة وحسن التأني. 4- التربية بالثناء والتشجيع.5-التربية بالتدرج ومراعاة الحال. 6- التربية بالأحداث المجتمعية . 7- التربية بالتواضع وإزالة الحواجز. 8-التربية بالإقناع. اما اهم النتائج كانت كالاتي: التربية بالقدوة الحسنة قدوة هي أفضل وسائل التربية على الإطلاق، لذلك انتهج الرسول (صلى الله عليه وسلم) ان يكون قدوة في كل شيء حسن ليمثله من حوله فكان خلقه القران ، فإذا استخدم المعلم او اي مربي مبدأ التشجيع والثناء بين صفوف الطلبة يكسبهم ويحبونه , لقد كان من اعجاز النبوة أن يكون أي حدث يمر على النبي –صلى الله عليه وسلم-يستفيد منه أي إفادة في تربية من حوله ليترسخ ذلك في افكارهم ويتعلموا الفراسة من تعاقب الأحداث؛ وهكذا ينبغي لنا في تربية المتعلمين لأعمال العقل ومعرفة الفوائد من الأحداث وتجنب الشرور فيصبح المسلم ذكيا فطنا في عاقب الايام
دور الوعي الاسري في ترصين البناء الفكري للفرد والمجتمع
Authors: Fadel Firas Saadoun , Hashem Mohammed Alyas 
Published: January 2023

الأسرة : هي الدرع الحصين، وأهل الرجل وعشيرته، ويطلق على الجماعة يربطها أمر مشترك , وهي الوحدة الأولى للمجتمع التي تكون العلاقات فيها في الغالب مباشرة ويتم داخلها تنشئة الفرد ويكتسب فيها الكثير من المعارف والمهارات والميول واتجاهاته في الحياة ويجد فيها أمنه وسكنه , ولقد عنى ديننا الحنيف بإعداد الاسرة وتهيئتها بشكل صحيح ، وفق نظام متقن للأسرة من صنع العليم الخبير الذى يعلم خفايا الأمور قبل ظواهرها، فهو خالق الإنسان ويعلم أسراره وخصائصه، وإذا كانت الأسرة أساس المجتمع، فإنَّ الزواج هو الأساس الأول الذي تتكون به الأسرة، ومن عناية الله وتكريمه للإنسان لم يجعله كغيره من المخلوقات يدع غرائزه تنطلق دون وعي ، بل وضع له النظام الملائم الذي يحفظ نسله وكرامته ، كل ذلك لأنها المرتكز الاساسي في تكوين شخصية الفرد وتوجهاته العقدية وبناء القدرات الفكرية والمعرفية لديه من خلال التنشئة الأسرية وهي عملية تعلم وتعليم وتربية.
الأمن الصحي الوقائي مفهومه ـ أهميّته ـ وسائل تحقيقه وفق المنظور القرآني
Authors: Mari Daham Mohi 
Published: January 2023

هذه الدراسة انّما هي خطوة اخرى في مسيرة الدراسات القرآنية التي تهدف الى بيان أهميّة الامن الصحي الوقائي ووسائل تحقيقه في ضوء القرآن الكريم.لذلك جاءت تحت عنوان (الأمن الصحي الوقائي مفهومه ـ أهميته ـ وسائل تحقيقه وفق المنظور القرآني ) مسترشداً على ذلك بتتبع واستقصاء الآيات القرآنية التي تدعوا الانسان الى تحقيق عملية الأمن الصحي الوقائي، عسى أن يكون خير مُعينٍ للإنسانية جمعاء ليُخرجها من أزمتها وليبصّرها بكيفية تحقيق مهمة الاستخلاف في الارض, واعادة أعمارها واقامة شرع الله تعالى فيها .
والذي نعنيه بالأمن الصحي الوقائي : هو اطمئنان الانسان من عدم وقوع أمر مكروه له أو لمجتمعه من وباء أومرض أو فايروس قاتل قد يصيبه او يصيب مجتمعه ؛ وذلك بحفظ الله تعالى وصيانته له, لاتّباعه شريعة الله سبحانه وتعالى والقيام بأوامره على اتم وجه, والامتناع عما نهى عنه الله تعالى ونبيه محمد (ﷺ).