bluuebunny/crossref_metadata_2025_split huggingface dataset:
Supporting Parents of Children With Type 1 Diabetes: Experiment Comparing Message and Delivery Types
Authors: Holtz Bree , Mitchell Katharine 
Published: February 2023

Background
Type 1 diabetes (T1D) is a chronic condition that typically affects young age group people and is estimated to afflict approximately 154,000 people younger than 20 years in the United States. Since T1D typically impacts children, parents must play an active role in helping their child manage the condition. This creates a substantial burden and responsibility for the parents.

Objective
This pilot study sought to find ways to help parents with children with T1D in coping with stresses related to managing and monitoring their child’s disease by providing informational support, either about parenting a child with T1D or general parenting messages through different channels.

Methods
Parents (N=120) of children with T1D were recruited through an email listserv through local T1D Facebook groups. A total of 102 participants were included in the analysis. We conducted a 2×2 experimental study over an 8-week period to test 2 types of messages (diabetes specific vs general parenting) and the medium in which the messages were delivered (Facebook vs SMS text message). Diabetes behavior, informational support, emotional support, and quality of life were the main outcomes of interest.

Results
The results suggested that the participants in the diabetes message groups showed improvement in diabetes behaviors (F1,99=3.69; P=.05) and were more satisfied with the intervention (F3,98=4.59; P=.005). There were no differences between message and medium groups on informational support, emotional support, or quality of life.

Conclusions
The results of this study demonstrate that the medium—Facebook or SMS text messaging—does not matter for parents’ perceptions of social support or quality of life. The diabetes message group reported higher levels of disease management. Finally, the groups with the diabetes support messages were more satisfied than those who received general parenting messages. The findings provide starting guidance for the development of social support interventions for this population.
Engagement and Utilization of a Complete Remote Digital Care Program for Musculoskeletal Pain Management in Urban and Rural Areas Across the United States: Longitudinal Cohort Study
Authors: Scheer Justin , Areias Anabela C , Molinos Maria , Janela Dora , Moulder Robert , Lains Jorge , Bento Virgílio , Yanamadala Vijay , Dias Correia Fernando , Costa Fabíola 
Published: February 2023

Background
Musculoskeletal (MSK) conditions are the number one cause of disability worldwide. Digital care programs (DCPs) for MSK pain management have arisen as alternative care delivery models to circumvent challenges in accessibility of conventional therapy. Despite the potential of DCPs to reduce inequities in accessing care, the outcomes of such interventions in rural and urban populations have yet to be studied.

Objective
The aim of this study was to assess the impact of urban or rural residency on engagement and clinical outcomes after a multimodal DCP for MSK pain.

Methods
This study consists of an ad hoc analysis of a decentralized single-arm investigation into engagement and clinical-related outcomes after a multimodal DCP in patients with MSK conditions. Patients were coded according to their zip codes to a specific rural-urban commuting area code and grouped into rural and urban cohorts. Changes in their engagement and clinical outcomes from baseline to program end were assessed. Latent growth curve analysis was performed to estimate change trajectories adjusting for the following covariates: age, gender, BMI, employment status, and pain acuity. Outcomes included engagement, self-reported pain, and the results of the Generalized Anxiety Disorder 7-item, Patient Health Questionnaire 9-item, and Work Productivity and Activity Impairment scales. A minimum clinically important difference (MCID) of 30% was considered for pain.

Results
Patients with urban and rural residency across the United States participated in the program (n=9992). A 73.8% (7378/9992) completion rate was observed. Both groups reported high satisfaction scores and similar engagement with exercise sessions, with rural residents showing higher engagement with educational content (P<.001) and higher program completion rates (P=.02). All groups showed a significant improvement in all clinical outcomes, including pain, mental health, and work productivity, without statistically significant intergroup differences. The percentage of patients meeting the MCID was similar in both groups (urban: 67.1%, rural: 68.3%; P=.30).

Conclusions
This study advocates for the utility of a DCP in improving access to MSK care in urban and rural areas alike, showcasing its potential to promote health equity. High engagement, satisfaction, and completion rates were noted in both groups, as well as significant improvements in clinical outcomes.

Trial Registration
ClinicalTrials.gov NCT04092946; https://clinicaltrials.gov/ct2/show/NCT04092946
SISTEM AKUNTABILITAS KINERJA INSTANSI PEMERINTAH: BEST PRACTICE PADA PEMERINTAH DAERAH DIY
Authors: Mardiarto Topaz 
Published: February 2023

The accountability of Local Government performance in Indonesia is low. This fact is based on the accountability system evaluation result conducted by Ministry of Administrative and Bureaucratic Reform (Kemenpan RB). Special Region of Yogyakarta (Daerah Istimewa Yogyakarta) Local Government in the last three years has become a region with the highest mark so that it becomes a reference for another region. The aim of this research is to formulate the best practice in the implementation of accountability system of government institution performance in DIY Local Government in order to be utilized by another region/institution. The informants of this research were those directly involved in the implementation of performance accountability systems in DIY Local Government comprising of Bappeda (Development Planning Board), Inspectorate, Organization Agency, and evaluator Kemenpan RB. Theory employed in this research is logic model theory to analyze performance planning and Friedman’s four quadrants to analyze performance measurement. The research result shows that a good performance accountability system must start from a good planning element. Planning system at least fulfill result oriented, alignment, interrelated causality, and synergetic criteria. Every constituted performance must have an indicator in order to be able to measure the achievement. In a good measuring system, every indicator must be able to be shown and accounted for to the society. To support the overall accountability system, e-government innovation must be used to facilitate implementation, monitoring, and evaluation of activities.
ANALISIS KESIAPAN AUDIT PAROKI KUMETIRAN YOGYAKARTA
Authors: Pratama Yohanes Mario 
Published: February 2023

INTISARI Paroki dapat dikategorikan sebagai salah satu organisasi nirlaba karena sumber dana paroki diperoleh melalui sumbangan para anggota gereja yang tidak mengharapkan imbalan. Tuhan mengharapkan supaya sumber keuangan di gereja selalu dijaga dengan baik karena sumber keuangan tersebut merupakan sumber daya milik Allah. Maraknya kasus korupsi gereja di Indonesia membuat Alexander Marwata (Wakil Ketua KPK) memberikan tantangan bagi gereja-gereja di Indonesia untuk diaudit supaya dapat meningkatkan transparansi dan akuntabilitas. Paroki Kumetiran Yogyakarta merupakan salah satu paroki terbesar di rayon kota Yogyakarta dan dapat menerima uang puluhan juta setiap bulannya. Berdasarkan hasil wawancara awal dengan Dewan Paroki Kumetiran, hingga saat ini Paroki Kumetiran belum pernah diaudit karena belum terdapat mandat atau aturan tertulis. Oleh karena itu, apabila nantinya rencana KPK untuk mengaudit gereja akan diwujudkan, Paroki Kumetiran harus memiliki auditabilitas yang baik supaya siap untuk diaudit. Penelitian ini bertujuan untuk menganalisis kesiapan Paroki Kumetiran Yogyakarta untuk diaudit menggunakan konsep auditabilitas dan audit readiness essentials. Penelitian ini merupakan penelitian kualitatif dengan pendekatan studi kasus. Pengumpulan data dilakukan menggunakan teknik wawancara mendalam, observasi, dan analisis dokumen. Partisipan penelitian yaitu pastor dan bendahara-bendahara paroki.Hasil penelitian ini menunjukkan bahwa Paroki Kumetiran Yogyakarta telah memenuhi komponen kesiapan sumber daya manusia, dukungan pemimpin, dan teknologi informasi. Meskipun sebagian besar komponen pengendalian internal dan dokumen pendukung sudah dilaksanakan dengan baik, namun Paroki Kumetiran Yogyakarta masih perlu memperbaiki pengendalian internal penghitungan uang yang terdapat di kotak gereja, dokumentasi bukti transaksi oleh bendahara lima, dan ketepatwaktuan laporan pertanggungjawaban.
Desain Manajemen Kos Kebun: Pedoman Akuntansi BUMN Perkebunan Berbasis IFRS yang Tidak Selaras dengan Statements on Auditing Standards (SAS) No. 101
Authors: Aliyya Dieni Nurul 
Published: February 2023

AbstrakTujuan – Penelitian ini bertujuan untuk menganalisis desain manajemen kos kebun dan hubungannya dengan audit serta kelangsungan usahanya.Metode Penelitian – Studi kasus dilakukan pada PT Perkebunan Nusantara (PTPN) VIII melalui teknik analisis dokumen, observasi, dan wawancara. Analisis dokumen paling utama dilakukan terhadap Pedoman Akuntansi BUMN Perkebunan Berbasis IFRS. Desain manajemen kos kebun dianalisis secara deskriptif melalui reduksi data, penyajian data, dan penarikan kesimpulan atas hubungannya dengan audit dan kelangsungan usaha perkebunan.Temuan – Hasil penelitian menunjukkan bahwa konsep dalam perlakuan akuntansi untuk kos kebun di PTPN VIII telah sesuai dengan prinsip pengakuan dan pembebanan kos (Suwardjono 2014) dan gambaran praktik perkebunan yang lazim (Kelsey 1994 dalam Plank dan Plank 1994). Namun, desain manajemen kos kebun yang diterapkan PTPN VIII masih bersifat global dengan menganggap semua blok kebun seolah-olah sama. Padahal, kondisi dan sifat tiap blok kebun berbeda sehingga dapat menciptakan pendapatan dan biaya yang berbeda pula.Originalitas – Penelitian ini menganalisis desain manajemen kos kebun yang diterapkan PTPN VIII karena belum ada standar manajemen kos kebun yang berterima secara umum.
ANALISIS KOMPETENSI AUDITOR INTERNAL TERHADAP KEMAMPUAN PENDETEKSIAN FRAUD
Authors: Hidayati Berlina 
Published: February 2023

Abstrak Seluruh organisasi baik organisasi bisnis dan nonbisnis menghadapi ancaman fraud yang sulit untuk dihindari. Fraud menyebabkan kerugian yang tidak dapat diperkirakan jumlahnya dengan pasti sehingga organisasi melalui auditor internal harus mampu melakukan mitigasi pada kasus fraud. Penelitian ini mendeskripsikan kompetensi auditor internal dan perlunya kompetensi tersebut terhadap kemampuan pendeteksian fraud. Penelitian ini menggunakan teori konstruktivisme dan teori kompetensi untuk mendeskripsikan kompetensi auditor internal dan pengembangannya dalam melaksanakan pekerjaan mereka, terutama yang berkaitan dengan kemampuan pendeteksian fraud. Penelitian ini menggunakan metode kualitatif dengan pendekatan studi kasus pada Satuan Internal Universitas Negeri Yogyakarta (SPI UNY) melalui teknik wawancara mendalam dan dokumentasi. Penelitian ini memanfaatkan rerangka kompetensi auditor internal The Institute Internal Auditor (IIA). Kompetensi auditor internal dianalisis secara deskriptif dengan reduksi data, penyajian secara naratif, dan penarikan simpulan terhadap kemampuan pendeteksian fraud yang melekat pada fungsi auditor internal SPI UNY.Penelitian ini menyimpulkan bahwa SPI UNY tidak memiliki dan memprioritaskan prosedur pendeteksian fraud sehingga kompetensi belum secara optimal dimanfaatkan untuk pendeteksian fraud. Auditor internal hanya mengandalkan firasat dan perasaan untuk pendeteksian fraud. Padahal, auditor internal telah memiliki kompetensi inti yang baik dalam pelaksanaan pekerjaan rutin.
EVALUASI PENGAUDITAN INTERNAL PENGADAAN BARANG DAN JASA PEMERINTAH (STUDI PADA INSPEKTORAT KABUPATEN TANA TORAJA)
Authors: Parinding Irene Ipal 
Published: February 2023

AbstrakTujuan – Tujuan penelitian ini mengevaluasi kesesuaian antara proses pengauditan internal pengadaan barang dan jasa (PBJ) yang dilakukan oleh Inspektorat Kabupaten Tana Toraja, Sulawesi Selatan dengan pedoman pengauditan internal PBJ dari Peraturan BPKP Nomor 3 Tahun 2019.Desain/Metodologi/Pendekatan – Penelitian ini merupakan penelitian kualitatif dengan pendekatan studi kasus pada Inspektorat Kabupaten Tana Toraja dengan mengevaluasi kesesuaian proses pengauditan internal PBJ yang riil dengan pedoman audit internal PBJ. Data yang digunakan yaitu data primer dan data sekunder. Penelitian menggunakan triangulasi teknik, yaitu kuesioner, wawancara, dan dokumentasi dan triangulasi sumber antara auditor dan auditi serta antara auditor dan auditor. Data dianalisis menggunakan rumus telaah sejawat dari AAIPI dan konsep Miles dan Huberman.Temuan – Hasil penelitian menunjukkan bahwa audit internal PBJ yang dilakukan di Inspektorat Kabupaten Tana Toraja telah cukup baik dengan skor keseluruhan 56%. Untuk perencanaan audit mendapatkan skor 82% tergolong baik, pelaksanaan audit mendapatkan skor 56% tergolong cukup baik, dan komunikasi audit mendapatkan skor 32% tergolong kurang baik. Hasil kuesioner didukung dengan hasil wawancara dan dokumentasi. Terdapat beberapa kendala dalam audit internal PBJ, yaitu penugasan audit belum terkoordinasi, jumlah penugasan yang tidak sesuai dengan rencana, audit bersifat formalitas, komitmen yang rendah, dan komunikasi yang belum efektif.Batasan/Implikasi – Penelitian ini memiliki implikasi pada Inspektorat Kabupaten Tana Toraja dalam melakukan audit internal PBJ agar sesuai dengan pedoman audit internal PBJ yang berlaku.Originalitas/Nilai – Audit internal PBJ bertujuan untuk memberikan keyakinan bahwa PBJ yang dilakukan oleh pemerintah telah efektif, efisien, terbuka, bersaing, transparan, adil, dan akuntabel. Inspektorat Kabupaten Tana Toraja sebagai bagian dari audit internal harus melakukan audit internal PBJ sesuai dengan pedoman audit dalam Peraturan BPKP Nomor 3 Tahun 2019. Penelitian ini adalah penelitian pertama yang dilakukan di Inspektorat Kabupaten Tana Toraja terkait PBJ.
ANALYZING THE IMPLEMENTATION OF VILLAGE FUND IN BANTUL REGENCY IN 2019 (A SYUDY IN TRIHARJO, KEBONAGUNG, AND NGESTIHARJO VILLAGE)
Authors: Mubarrok Zaennul 
Published: February 2023

The realization of village fund as reported by the head of the village office department and the village secretary of Bantul Regency in 2017 revealed that three villages in Bantul Regency showed low realization of the fund, namely Triharjo 64.43%, Kebonagung 61.91%, and Ngestiharjo 69.19%. This research was to explore the implementation of village fund in Bantul Regency in 2017 (A Study in Triharjo, Kebonagung and Ngestiharjo Village), to identify problems that occurred, and to find solutions to the problems. It was qualitative research with a case study approach. Data were collected through interviews, document analyses, and direct observations in three villages in Bantul Regency, namely Triharjo, Kebonagung and Ngestiharjo. The results indicated that the implementation of the fund in the three villages in 2017 was not satisfactory yet as indicated by the low realization of the fund. The problems can be attributed to the low capacity of the village apparatus and regulation constraints. In addition to this, they could not yet perform planning, responsibility, and programs.
SARS-CoV-2 RNA-dependent RNA polymerase as a target for high-throughput drug screening
Authors: Wu Jiahui , Chen Zhiqiang , Han Xue , Chen Qiaoqiao , Wang Yintao , Feng Tingting 
Published: February 2023

The ongoing COVID-19 pandemic caused by the SARS-CoV-2 has necessitated rapid development of drug screening tools. RNA-dependent RNA polymerase (RdRp) is a promising target due to its essential functions in replication and transcription of viral genome. To date, through minimal RNA synthesizing machinery established from cryo-electron microscopy structural data, there has been development of high-throughput screening assays for directly screening inhibitors that target the SARS-CoV-2 RdRp. Here, we analyze and present verified techniques that could be used to discover potential anti-RdRp agents or repurposing of approved drugs to target the SARS-CoV-2 RdRp. In addition, we highlight the characteristics and application value of cell-free or cell-based assays in drug discovery.
Possibilities of differential diagnostics of livores mortis and bruises at different stages of the time since death using laser polarization methods
Authors: Voronov V.T. 
Published: February 2023

One of the urgent problems of forensic medicine remains the detection of hemorrhages in soft tissues during examinations of decayed corpses, because late cadaveric phenomena significantly distort the primary morphological picture, thereby complicating the examination. A change in the color of the skin after a few days or later after death most often makes the macroscopic diagnosis of hemorrhages impossible, in particular, their differentiation with livores mortis.The aim of work. To investigate the possibilities of detecting and differentiating bruises in areas of livores mortis at different stages of the time since death by the Muller matrix analysis of polarization images of optically anisotropic polycrystalline networks of human soft tissues.
Material and methods. Skin sections with subcutaneous fatty tissue were collected from corpses of persons who died from mechanical injuries. The obtained samples were divided into two groups: intact samples of livores mortis at the stages of hypostasis and imbibition and with existing hemorrhages with a known time since death. Tissue research was carried out using a laser polarimeter of a standard scheme.Results. According to the results of the study, it was established that the values of the statistical moments of the 3rd and 4th orders (S3, S4) of the intensity distributions of laser images of the skin show a statistically significant (р1<0,001) difference between intact areas and when bruises and livores mortis are combined. The values of asymmetry and excess (S3 from 1,23±0,032 to 1,56±0,038; S4 from 1,49±0,024 to 1,94±0,021) for intact samples of livores mortis changed with increasing interval of time since death. Similar changes in S3 and S4 (S3 from 1,54±0,031 to 1,83±0,037; S3from 1,82±0,026 to 2,11±0,023) for skin samples in the areas of localization of livores mortis with existing bruises.Conclusions. Thus, it can be stated that the application of the Mueller matrix analysis method of polarization images of optically anisotropic polycrystalline networks of soft human tissues is effective in detecting and differentiating bruises in the areas of cadaveric spots at different stages of the postmortem interval by conducting a statistical analysis of the values of the statistical moments of 3rd and 4th order.
The role of polymorphism of AGT genes (rs4762) and GNB3 (rs5443) in the development of essential hypertension
Authors: Voroniuk K.O. , Sydorchuk L.P. 
Published: February 2023

Assess the role of the polymorphism of AGT genes (rs4762) and GNB3 genes (rs5443) in the development of the essential arterial hypertension separately and by combining their polymorphic variants.Material and methods. The case-control study involved 100 patients with EAH stage II, 1-3 degrees of blood pressure (BP), high and very high cardiovascular risk. Among the patients, 21% (21) constituted men, and 79%(79) were women. The mean age of patients was 59.86±6.22 y.o. The control group comprised 60 almost healthy individuals, relevant in age (49.13±6.28y.o.) and gender distribution (63% - women, 37% - men). To study of polymorphism of AGT (rs4762) and GNB3 (rs5443) genes, we performed a qualitative polymerase chain reaction (PCR) in real time.Results. In patients with EAG residents of Northern Bukovyna mutated T-allele of AGT gene (rs4762) is found in 15,97% of cases, which is more frequent than in practically healthy by 9,72% (p=0,023); mutations of AGT gene in homozygous species in the control group have not met at all. Binary logistic regression confirmed an increase in the risk of inheriting EAH according to dominant and additive models in carriers of the minor T-allele of the AGT gene (rs4762) almost 3 times higher than in homozygotes for the major C-allele (р=0,04 і р=0,03). Inheritance of EAH is not associated with polymorphic variants of the GNB3 gene (rs5443).
Conclusions. Тhe T-allele of the AGT gene (rs4762) increases the risk of development of EAH almost 3 times, while the polymorphic variants of the GNB3 gene (rs5443) are not the predictors of the emergence of EAH in the population.
Profil Faktor Risiko Dan Sosiodemografis Kanker Serviks-: Sebuah Kajian Sistematis
Authors: Santosa Winnie Nirmala , Mago Helen Cyntia 
Published: February 2023

Cervical cancer is caused by HPV infection type 16 and 18. The risk factors and sociodemographic of HPV transmission is age, parity, number of sexual partners, oral contraceptives, sexual intercourse at young age and education level. The aims is to describe and analyze risk factors and sociodemographic of cervical cancer. This research is a systematic review. There are nine studies that included. The results are the mean age around 31.5-42.8 years old, the number of sexual partners between 0 - ≥ 2, with or without of oral contraceptives, have sexual intercourse at 16-24 years old, have children with 0-8 number of parity, and have an education level between lower - higher education level. This profile of risk factors and sociodemographic can be different between each country depends on culture, government systems and economic status from each country. The conclusion is women aged ≥ 30 years old (mean age around 31,5-42,8 years old) who used or doesn’t used oral contraceptive and have sexual intercourse at young age around 16-20 years old with the number of sexual partner is ≥ 1, also have high number of parity or have ≥ 2 kids and have low education level.
Behavioural Assessment on Influence of Adjacently Placed Strip Footings at Different Embedment Level
Authors: Ekbote Anupkumar G. , Nainegali Lohitkumar , Rajhans Puja , Deepak M S 
Published: February 2023

Abstract
The footings laid in close proximity imposes a definite change in the behaviour of the adjacent footing, subsequently changing the behaviour of the nearby footings. The present study emphasises the behaviour of the nearby strip footings embedded at a different level by adopting the commercially available finite element analysis program, ABAQUS. The load-settlement behaviour, ultimate bearing capacity (UBC), and the failure patterns of adjacent strip footings are assessed by considering the Mohr-Coulomb failure criterion. The UBC is of the nearby footings (left and right) are estimated and represented in terms of interference factors (ξL/ξR
) defined as the UBC of a footing in the presence of adjacent footing to that of same considered for equivalent isolated footing. The results reveal that a significant influence of the adjacent footing is experienced when the spacing between the footings (S/B) is lesser, and they behave as the single footing of greater width at S/B = 0.25 irrespective of the level of embedment depth. Furthermore, the influence of interference increases with the increase in the embedment depth of adjacent footing. It is found that the ξL
is significantly more for a lower level of embedment depth, and the same increases with an increase in the embedment depth of the right footing but on the contrary ξR
decreases. The increase in the peak interference factor, ξL-max
for DL/B = 0.5 is 2.1% and 4.2% when DR/B = 0.75 and DR/B = 1.0, respectively.