bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nocturia is associated with stiffer central artery and more likely development of major adverse cardiovascular events in men
Authors: Chan C. K. , Ng Chi Fai , Yuen Steffi K. K. , Lau B. S. Y. , Yee C. H. , Teoh J. Y. C. , Chiu P. K. F. , Kwok S. W. 
Published: January 2023

ObjectivesTo study the association between nocturia and brachial-ankle pulse wave velocity (baPWV) [surrogate of central arterial stiffness (CAS)] in men and to explore this association on predicting major adverse cardiovascular events (MACE).Methods246 consecutive men (mean age:68.1 ± 8.4, range 36-88) newly referred to urology clinic for male-lower urinary tract symptoms(mLUTS)/nocturia were recruited. Their bilateral baPWV were measured by automatic pulse waveform analyzer. The associations between baseline characteristics, mLUTS/nocturia and baPWV(&gt;1800cm/sec) [significant CAS] were analyzed by multivariate logistic regression. We followed the cohort for a median period of 27.5 months. Cox proportional hazard regression analysis and Kaplan-Meier method were used to study factors predicting MACE.ResultsThe mean ( ± SE) baPWV of our cohort was 1820 ± 16cm/sec. For comparison, the reported value of the general population of similar age structure was~1650cm/sec. IPSS (total) was not associated with baPWV, whereas IPSS-Question.7(nocturia) was significantly increased with baPWV in men&lt;70yo [nocturia=1.6 ± 1.14, 2.1 ± 1.08, 2.67 ± 1.33) for baPWV(cm/sec) &lt;1400, 1400-1800, &gt;1800 respectively] (P-trend=0.002). Age≥70yo (OR:2.70, 95%CI:1.52-4.76), diabetes mellitus (OR:2.26, 95%CI:1.06-4.83), hypertension (OR:1.95, 95%CI:1.10-3.45) and nocturia≥3x/night (OR:1.75, 95%CI:1.02-3.12) independently determined baPWV&gt;1800cm/sec. The cumulative incidence rate of MACE was 46.8/1000 man-years(95%CI:30.96-68.16/1000). The addition of nocturia≥3x/night and baPWV&gt;1800 cm/sec to the basic model improved the prediction of the development of MACE (difference in -2 log likelihood value: 11.219, p&lt;0.001). Past history of ischemic heart (HR:5.67, 95%CI:2.02-15.88), nocturia≥3x/night (HR:2.87, 95%CI: 0.94-8.76) and baPWV&gt;1800cm/sec (HR:5.16, 95%CI:1.79-14.90) independently predicted MACE in men.ConclusionMen attending the urology clinic for male-LUTS/nocturia had higher baPWV. This association was more pronounced in men&lt;70yo. Men presented with both nocturia≥3x/night and baPWV&gt;1800cm/sec showed significant predilection for developing MACE.
Diversity of the fecal microbiota in Chinese ponies
Authors: Lv Shipeng , Zhang Yanli , Zhang Zhengkai , Meng Sihan , Pu Yabin , Liu Xuexue , Liu Lingling , Ma Yuehui , Liu Wujun , Jiang Lin 
Published: January 2023

IntroductionThe gut microbiomes of equine are plentiful and intricate, which plays an important part in the growth. However, there is a relative lack of information on the microbial diversity in the pony's gut.MethodsIn this article, 118 fecal samples from DeBa pony, NiQi pony and GuZh horse were studied by 16S rRNA amplicon sequencing.ResultsDiversity analysis was used to determine the difference of gut microbiota composition among different breeds. Alpha diversity analysis showed that the gut microbiota of NiQi ponies were abundant and various. Beta diversity analysis showed that the microorganisms constitution of DeBa ponies was more similar to that of NiQi ponies. LDA Effect Size (LEfSe) analysis result that the microorganism biomarkers for NiQi pony at the genus level were Phascolarctobacterium, Paludibacter, and Fibrobacter; the bacterial biomarker for DeBa pony was Streptococcus and Prevotella; and the bacterial biomarkers for GuZh horses was Treponema, Treponema Mogibacterium, Adlercreutzia, and Blautia. The correlation analysis between genera with &gt;1% abundance and horse height found that Streptococcus (P &lt; 0.01), Treponema (P &lt; 0.01), Coprococcus (P &lt; 0.01), Prevotella (P &lt; 0.01), Phascolarctobacterium (P &lt; 0.01), and Mogibacterium (P &lt; 0.01) were significantly associated with horses' height. The functional prediction results indicated that DeBa pony have a microbiota functional more similar to NiQi pony.DiscussionFor the first time, our results announce the species composition and structure of the gut microbiota in Chinese ponies. At the same time, our results can provide theoretical reference for further understanding the healthy breeding, feeding management and disease prevention of horses.
A comparative study of eight serological methods shows that spike protein-based ELISAs are the most accurate tests for serodiagnosing SARS-CoV-2 infections in cats and dogs
Authors: Diezma-Díaz Carlos , Álvarez-García Gema , Regidor-Cerrillo Javier , Miró Guadalupe , Villanueva-Saz Sergio , Dolores Pérez María , Verde María Teresa , Galán-Malo Patricia , Brun Alejandro , Moreno Sandra , Checa Rocío , Montoya Ana , Van Voorhis Wesley C. , Ortega-Mora Luis Miguel 
Published: January 2023

IntroductionCoronavirus disease 2019 (COVID-19) is an infectious zoonotic disease caused by SARS-CoV-2. Monitoring the infection in pets is recommended for human disease surveillance, prevention, and control since the virus can spread from people to animals during close contact. Several diagnostic tests have been adapted from humans to animals, but limited data on the validation process are available.MethodsHerein, the first comparative study of six “in house” and two commercial serological tests developed to monitor SARS-CoV-2 infection in pets was performed with a well-coded panel of sera (61 cat sera and 74 dog sera) with a conservative criterion (viral seroneutralisation and/or RT–qPCR results) as a reference. Four “in house” tests based on either the RBD fragment of the spike protein (RBD-S) or the N-terminal fragment of the nucleoprotein (N) were developed for the first time. The analytical specificity (ASp) of those tests that showed the best diagnostic performance was assessed. The validation included the analysis of a panel of sera obtained pre-pandemic from cats and dogs infected with other coronaviruses to determine the analytical Sp (17 cat sera and 41 dog sera).Results and discussionELISAS based on the S protein are recommended in serosurveillance studies for cats (RBD-S SALUVET ELISA, ELISA COVID UNIZAR and INgezim® COVID 19 S VET) and dogs (INgezim® COVID 19 S VET and RBD-S SALUVET ELISA). These tests showed higher diagnostic sensitivity (Se) and DSp in cats (&gt;90%) than in dogs. When sera obtained prior to the pandemic and from animals infected with other coronaviruses were analyzed by RBD-S and N SALUVET ELISAs and INgezim® COVID 19 S VET, a few cross reactors or no cross reactions were detected when dog and cat sera were analyzed by tests based on the S protein, respectively. In contrast, the number of cross reactions increased when the test was based on the N protein. Thus, the use of tests based on the N protein was discarded for serodiagnosis purposes. The results obtained revealed the most accurate serological tests for each species. Further studies should attempt to improve the diagnostic performance of serological tests developed for dogs.
Etika Bermedia Sosial Dalam Perseperktif NU
Authors: Ahmad Faruqi , Niam Misbachun , Fatmawati Novita , Uyun Aimmatul , Firdaus Isnaini Nur Nabila , Zulfahmi Muhammad Nofan 
Published: January 2023

Abstract This research aims to find out the teachings of Nahdlatul Ulama in regulating morals or ethics in social media. So far, we know that social media is often misused in practice, such as: hate speech, spreading propaganda to fake news. so that it can lead to national disintegration and division. The method used in this research is descriptive qualitative with a literature review approach. the author found a number of explanations of the ethics of social media in the teachings of Nahdlatul Ulama which originate in the Al-Qur'an, Hadith, and other books. The research concludes that in the teachings of Nahdlatul Ulama it has provided various guidelines in using social media. The inculcation of ethics in social media by Nahdlatul Ulama is proven by the existence of various concepts of social media, starting from how to communicate properly to how to process news and its prohibitions. Nahdlatul Ulama explains the prohibitions or limitations contained in various explanations originating from the Al Quran, Hadith, and the books of the Nahdlatul Ulama community. Suggestions for readers should be ethical or moral in exploring the world of social media.Keywords : Ethics, social media, NUAbstrakRiset ini memiliki tujuan untuk mengetahui ajaran Nahdlatul Ulama dalam mengatur akhlak atau etika dalam bermedia sosial. selama ini, kita ketahui bahwa media sosial sering disalah gunakan dalam praktiknya, seperti: ujaran kebencian, menebar propaganda sampai berita bohong. sehingga dapat menimbulkan disintegrasi bangsa dan perpecahan. metode yang dipergunakan dalam penelitian ini adalah deskriptif kualitatif dengan pendekatan kajian pustaka. penulis menemukan sejumlah penjelasan etika bermedia sosial dalam ajaran Nahdlatul Ulama yang bersumber dalam Al-Qur’an, Hadist, dan kitab-kitab. Penelitian menyimpulkan bahwa didalam ajaran Nahdlatul Ulama telah memberikan berbagai tuntunan dalam bermedia sosial. Penanaman etika dalam bermedia sosial oleh Nahdlatul Ulama dibuktikan dengan adanya berbagai Konsep bermedia sosial, mulai dari cara berkomunikasi dengan baik sampai cara mengolah sebuah berita beserta larangannya. Nahdlatul Ulama menjelaskan larangan atau batasan yang terdapat dalam berbagai penjelasan bersumber dari Al Quran, Hadist, dan kitab-kitab masyarakat Nahdlatul Ulama. Saran bagi pembaca hendaklah beretika atau berakhlak dalam menjelajahi dunia media sosial.Kata Kunci : Etika, sosial media, NU
Hamartomatosis biliar múltiple o enfermedad de Von Meyenburg.
Authors: Salada Morales Rocio , Marino Karenina , Castelli Fernando 
Published: January 2023

La hamartomatosis biliar múltiple o enfermedad de Von Meyenburg es una lesión hepática benigna poco frecuente .Consiste en la deformación y desorganización de los conductos biliares debido a un defecto en la involución de placas ductales embrionarias.Generalmente los pacientes son asintomáticos y el diagnóstico es incidental. Se debe tener en cuenta diagnósticos diferenciales tales como carcinoma hepatocelular difuso, metástasis hepáticas múltiples y quistes hepáticos múltiples Presentamos el caso de una paciente de 35 años monorrena congénita que consulta por dolor abdominal inespecífico. La ecografía abdominal informa múltiples lesiones hepáticas que no logra clasificar. Se realiza resonancia magnética en la cual se observan incontables lesiones hiperintensas en T2 subcentimétricas. En la secuencia colangiográfica, no se observa comunicación con los ductos biliares conformando la clásica imagen en cielo estrellado Dadas las características clínico-imagenológicas se realiza diagnóstico de hamartomatosis biliar múltiple. La paciente permanece clínicamente asintomática con hepatograma normal por lo que se decide seguimiento clínico imagenológico anual.
Tratamiento quirúrgico de la enfermedad pilonidal sacrocoxígea. Experiencia de un centro en los últimos 4 años.
Authors: Pruzzo Garate Matias Felipe , Via Dorado Campora Jose Ignacio , Sanchez Baez María José , Readi Vallejos Alejandro Nicolás , Rodriguez Gonzalez Marcelo Andrés , Campaña Villegas Gonzalo Alfredo 
Published: January 2023

Objetivo: Evaluar los resultados a largo plazo en el tratamiento quirúrgico de la enfermedad pilonidal sacrocoxígea (EPS) comparando las diferentes técnicas quirúrgicas utilizadas, complicaciones, tiempo de cicatrización y recidiva.Material y método: Estudio trasversal retrospectivo. Se revisaron las fichas de los pacientes intervenidos por EPS entre enero 2017 hasta agosto 2021. Para el seguimiento se obtuvo la información desde los registros de los controles periódicos en nuestro centro y aquellos que no continuaron con estos controles se contactaron telefónicamente.Resultados: Se recopilaron 309 casos, con una media de seguimiento de 15,6 meses. Las técnicas más utilizadas para la fase crónica de EPS fueron marsupialización y Karydakis, con tiempo de cicatrización completa de 54,5 y 18,2 días, respectivamente. La presencia de complicaciones prolongó el tiempo de cicatrización en 46,5 días en Karydakis, con mínimo impacto en marsupialización. La tasa de recidiva fue menor en Karydakis y en etapa aguda cuando se realiza destechamiento y legrado. La profilaxis antibiótica no afectó el riesgo de complicaciones postoperatorias.Discusión: El desarrollo de complicaciones postoperatorias tiene mayor impacto en la cicatrización de la técnica cerrada que en la abierta, siendo esta última más tolerante en cuanto a la cicatrización frente a complicaciones.Conclusión: La intervención con técnica de Karydakis logra la cicatrización de la herida operatorio en menor tiempo que la marsupialización, sin embargo, al desarrollar complicaciones, este tiempo aumenta 3,5 veces más. La recurrencia fue menor en Karydakis. En absceso se recomienda el desteche y legrado por sobre el drenaje exclusivo.
PENERAPAN PROGRAM SUSTAINABLE DEVELOPMENT GOALS (SDGs) DESA POLEWALI DALAM MENGURANGI KEMISKINAN
Authors: Nawir Adi , Syamsuddin Syamsuddin , Jusniaty Jusniaty 
Published: January 2023

Program Sustainable Development Goals (SDGs) di Desa Polewali dalam mengurangi angka kemiskinan. Menggunakan jenis penelitian Kualitatif. Hasil penelitian mengemukakan bahwa penerapan Program Sustainable Development Goals (SDGs) Desa Polewali telah diterapkan sesuai dengan surat edaran Kementrian Desa tentang pelaksanaan Program SDGs. Meskipun Program SDGs ini masih dalam tahap perencanaan bagaiamana program keberlanjutan, terkait dari implementasi Sustainable Development Goals (SDGs) ini masih belum dirasakan oleh masyarakat Desa Polewali, namun untuk penerapanya sudah terlaksana dengan baik. Dilihat dari Pemerintah Desa yang telah melakuakan pendataan langsung kepada masyarakat dengan pembaharuan data 1 kali dalam 3 bulan. Hasil dari pendataan inilah yang akan menjadi acuan dari Pemerintah itu sendiri untuk melakukan perencanaan Desa mulai dari perencanaan pembanguanan dan strategi yang harus dilakukan dalam hal khususnya di bidang kemiskinan. Pemerintah Desa Polewali dalam penerapan program SDGs untuk mengurangi angka kemiskinan telah melakukan hal yang mampu mengurangi tingkat angka kemiskinan di Desa Polewali sesuai dengan tujuan dari program SDGs yaitu: meningkatkan pendapatan masyarakat miskin, menjamin akses terhadap pelayanan desa, dan melindungi seluruh masyarakat dari segala bentuk bencana.Kata kunci: Penerapan, Sustainable Development Goals, Kemiskinan, Pemerintah Desa
IMPLEMENTASI PRINSIP GOOD GOVERNANCE TERHADAP EFEKTIFITAS PELAYANAN PUBLIK DINAS KEPENDUDUKAN DAN PENCATATAN SIPIL
Authors: Tahir Supratman 
Published: January 2023

This study aims to determine the implementation of the principles of good governance on the effectiveness of public services at the Department of Population and Civil Registration of Bone Regency. This research was conducted using a qualitative approach with a descriptive (type) format. Data collection techniques used in this study include: observation, interviews, documentation. The data analysis techniques used are: data reduction, data presentation and conclusion drawing. The results of this study state that: (1) Implementation of Good Governance Principles on the Effectiveness of Public Services at the Population and Civil Registration Office of Bone Regency has not been fully effective, directed and systematic, in providing public services to the community in accordance with the expectations and needs of the community. Judging from the characteristics of the principles of good governance that have been applied as follows: accountability, transparency, participation and the rule of law. And one of them has not been running effectively, namely the principle of accountability while the principles of transparency, participation, and the rule of law have been quite effective in accordance with the expectations and needs of the community. (2) The factors that influence the implementation of the principles of good governance on the effectiveness of public services at the Department of Population and Civil Registration of Bone Regency can be seen from the availability of adequate facilities and infrastructure. Keywords: Good Governance, Effectiveness, Public Service
«I WILL GIVE YOU THE RIGHT WORD...» (N.A. NEKRASOV'S WINGED EXPRESSIONS IN THE RUSSIAN LANGUAGE SPACE)
Authors: Кольцова Л.М. , Чуриков С.А. 
Published: January 2023

В статье, посвященной двухсотлетию великого русского поэта Николая Алексеевича Некрасова, рассматриваются крылатые выражения поэта, широко представленные в русской речи второй половины XIX - начала XXI веков. Опираясь на проведенное исследование, авторы называют наиболее частотные крылатые строки Н.А. Некрасова и указывают на то, что общее число крылатых единиц, восходящих к его произведениям, более трехсот. На примере пяти широко употребительных некрасовских фраз демонстрируются особенности бытования «крылатики» Н.А. Некрасова в текстах различных стилей и жанров. Полученные данные не оставляют сомнений в том, что Н.А. Некрасов относится к числу самых цитируемых русских писателей, а многие строки из его поэтических произведений входят в ядро фонда крылатых единиц отечественной культуры, превратившись в общенациональные афоризмы.
The article, dedicated to the bicentennial of the great Russian poet Nikolai Alekseevich Nekrasov, examines the poet's winged expressions, widely represented in Russian speech in the second half of the 19th - early 21st centuries. Based on the conducted research, the authors list the most frequent catch phrases of N.A. Nekrasov and indicate that the total number of his catchphrases exceeds 300. On the example of five widely used Nekrasov phrases, the features of the existence of the winged expressions of N.A. Nekrasov in texts of various styles and genres.The data obtained show that N.A. Nekrasov is one of the most cited Russian writers, and many lines from his poetic works are included in the core of the fund of winged units of Russian culture, turning into nationwide aphorisms.
SOUND IMAGES IN M.A. VOLOSHIN'S COLLECTION “DEMONS DEAF” AND A.A.BLOCK’S POEM “TWELVE”
Authors: Логвинова И.В. , Шульдишова А.А. 
Published: January 2023

В статье исследуются звуковые образы в стихотворениях сборника М.А. Волошина «Демоны глухонемые» (1919) и поэме А.А. Блока «Двенадцать». Констатируется, что в них у обоих авторов запечатлена музыка революции. Представляется, что в сборнике М.А. Волошина звуковые образы репрезентируют предреволюционное состояние, немую музыку приближающейся катастрофы, а звуковые образы в поэме А.А. Блока предстают как заговорившие «демоны» революции, музыка уже свершившейся революции. В целом звуковые образы сборника Волошина «Демоны глухонемые» можно рассматривать как своеобразный диалог-дискуссию с музыкой революции у Блока, при котором визуальные образы выступают звуковыми, заставляя вспомнить библейское выражение «и камни заговорят». Установлено, что у Блока они - символы революции, а у Волошина - перерастают в многозначные метафоры революции. Прослеживается связь между историческими событиями и тем, как они были поняты, «услышаны» и интерпретированы поэтами-современниками. Анализу подверглись стихотворения из сборника М.А. Волошина «Демоны глухонемые», поэма А.А. Блока «Двенадцать», стихотворение М.А. Волошина «Северовосток». На примерах указанных произведений Волошина и Блока показано основное мироощущение революционной, неспокойной эпохи.
The article explores sound images in the poems of M.A. Voloshin's collection «Demons Deaf» (1919) and the poem by A.A. Blok «Twelve». It seems that in the collection of MA Voloshin the sound images represent the pre-revolutionary state, the silent music of the approaching catastrophe, and the sound images in the poem by A. A. Blok appear as the “demons” of the revolution, the music of the revolution that has already taken place. It seems that in the collection of MA Voloshin the sound images represent the pre-revolutionary state, the silent music of the approaching catastrophe, and the sound images in the poem by A. A. Blok appear as the “demons” of the revolution, the music of the revolution that has already taken place. It is stated that in both authors the music of the revolution is captured. On the whole, the sound images of Voloshin’s collection «Deaf-mute demons» can be seen as a dialogue with the music of the revolution in Blok's poetry, in which visual images act as sound. They make you remember the biblical expression «and the stones will speak». It has been established that for Blok they are symbols of the revolution, while for Voloshin they develop into ambiguous metaphors of revolution. The article traces the connection between historical events and how they were understood, «heard» and interpreted by contemporary poets. The analysis included poems from M. Voloshin's collection “Deaf-mute Demons”, A. Blok’s poem “Twelve”, M. Voloshin’s poem “Severovostok”. The examples of these works by Voloshin and Blok are used to show the basic attitude of the revolutionary, turbulent era.
VORONEZH LINGUISTIC LOCAL HISTORY IN THE 21ST CENTURY: RESEARCH DIRECTIONS, DEVELOPMENT PROSPECTS
Authors: Верховых Л.Н. 
Published: January 2023

В статье охарактеризованы направления лингвокраеведческой работы в Воронежской области, обозначены основные пути развития воронежского лингвокраеведения. Установлено, что важными направлениями лингвокраеведческой работы в XXI веке являются научно-исследовательская, издательско-просветительская и лингвометодическая. В процессе анализа научных работ в области воронежского лингвокраеведения автор приходит к выводу, что ведущая роль в организации системной лингвокраеведческой работы в Воронежской области принадлежит кафедре славянской филологии, научной лаборатории воронежского лингвокраеведения им. профессора В.И. Собинниковой и Воронежской ономастической школе под руководством профессора Г.Ф. Ковалева (Воронежский государственный университет). Перспективы воронежского лингвокраеведения определяются актуализировавшимися в современной лингвистике принципами и связаны с развитием полипарадигмальных исследований, лексикографическим описанием языковых единиц Воронежской области, а также с более широким изучением литературной ономастики края. Важной перспективной задачей является издание «Ономастической энциклопедии Воронежской области».
The article describes the directions of linguistic local history work in the Voronezh region, outlines the main ways of development of Voronezh linguistic local history. It has been established that the important areas of linguistic local history work in the 21st century are research, publishing and educational, and linguo-methodological. In the process of analyzing scientific works in the field of Voronezh linguistic local history, the author comes to the conclusion that the leading role in the organization of systematic linguistic local history work in the Voronezh region belongs to the Department of Slavic Philology, the scientific laboratory of Voronezh linguistic local history named after V.I. professor V.I. Sobinnikova and the Voronezh onomastic school under the guidance of Professor G.F. Kovalev (Voronezh State University).The prospects of Voronezh linguistic regional studies are determined by the principles that have become actual in modern linguistics and are associated with the development of polyparadigm studies, the lexicographic description of the language units of the Voronezh region, as well as with a broader study of the literary onomastics of the region. An important long-term task is the publication of the Onomastic Encyclopedia of the Voronezh Region.