bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Association of Marital Status with Kidney Cancer Surgery Morbidity - A Retrospective Cohort Study
Authors: Tang Yuzhe , Valovska Marie-Thérèse , Nolazco José , Yim Kendrick , Chung Benjamin , Chang Steven 
Published: June 2023

Abstract
Purpose:
To better understand whether the marital status impacts 90-day postoperative outcomes following kidney cancer surgery.
Methods:
We performed a retrospective cohort study of adult patients undergoing elective partial or radical nephrectomy to manage kidney masses from 2003 to 2017 using the Premier Hospital Database, a national hospital discharge dataset. Multinomial logistic regression models controlling for a wide range of clinicodemographic, surgical, and hospital characteristics were used to assess an association between marital status and postoperative complications. The primary outcome was 90-day complications, including minor complications (Clavien grades 1-2), non-fatal major complications (Clavien grades 3-4), and mortality (Clavien grade 5). Secondary outcomes included patient disposition and readmission rates.
Results:
The study cohort comprised 106,752 patients, of which 61,188 (57.32%) were married. The overall incidence of minor complications, major complications, and death was 24.04%, 6.00%, and 0.71%, respectively. Marriage was associated with a significantly lower incidence of minor (OR 0.97; 95% CI: 0.94-0.99) complications following open or radical nephrectomy and major complications (OR 0.89; 95% CI: 0.84-0.95) for all surgical types and approaches (Figure 1). There was no association between marital status and mortality (OR 0.94; 95% CI: 0.81-1.10).
Conclusions:
Marriage is associated with a significant reduction in major complications following kidney cancer surgery, likely because it is associated with greater social support, which is beneficial in the postoperative phase of care. Marital status and social support may play a role in the preoperative decision-making process and counseling for patients considering kidney cancer surgery.
Assessment of river recreation safety using spatial river recreational index by integration of hydrodynamic model and fuzzy logic
Authors: Kwon Siyoon , Seo Il Won , Kim Byunguk , Jung Sung Hyun , Kim Yong Do 
Published: June 2023

Abstract
As the demand for recreational activities in rivers has increased, the assessment of the existing safety measures of these activities has become crucial to prevent accidents. Current safety measures have mainly focused on water quality factors, while the safety of in-water activities is also influenced by river hydraulic conditions. Hence, we proposed a spatial river recreational index (SRRI) that considers hydraulic parameters to evaluate the safety of recreational activities in rivers. Using a 3D hydrodynamic model, we reproduced the spatial distribution of hydraulic parameters under various discharge conditions to estimate the SRRI based on fuzzy logic. The application of the SRRI at the confluence of the Nakdong-Guemho River in South Korea revealed that each hydraulic parameter contributed differently to the safety according to discharge and morphological conditions. For instance, flow direction decreased safety in the near-field of the river confluence, while water depth played a significant role in the meandering reach of the Nakdong River. Flow velocity was the most critical factor for nonpowered activities, such as sailing and paddling/wading, under high-flow conditions. Sailing was found to be unsafe in the main flow zone and near-field of the river confluence due to its sensitivity to discharge change. In contrast, paddling/wading and leisure boats were less sensitive to discharge changes and could be partly allowed under high-flow conditions, except in the deep-water zone in the meandering reach. Therefore, SRRI is expected to help many users with safe recreational activities in rivers by providing spatial safety information based on various hydraulic conditions.
Influence of Changes in OM Content and Form on the Adsorption of Two Typical Antibiotics to SPM
Authors: Shen Zihao , Sun Yali , Yang Ye , Zheng Xiaolan , Shang Jingge , Liu Yanhua , Guo Ruixin , Chen Jianqiu , Liao Qianjiahua 
Published: June 2023

Abstract
Antibiotics are commonly detected in natural waters. Suspended particulate matter (SPM) in surface water has a good adsorption capacity for antibiotics, and the organic matter (OM) in SPM is the key factor for this adsorption. We investigated the contribution of OM content and form to the adsorption of tetracycline (TC) and norfloxacin (NOR) in the SPM of Taihu Lake. To change the content and form of OM in SPM, we burned it at 505 ℃ and oxidised it with H2O2, respectively. The OM in the sample that was combusted (expressed as SPM-505 ℃) was almost entirely eliminated, and the adsorption amount of TC decreased by 14.8% when compared to the original sample, while the adsorption amount of NOR decreased by 64.8%, indicating that OM content contributes to the adsorption of antibiotics. Although the OM content in the oxidised sample (expressed as SPM-H2O2) decreased, the adsorption amounts of TC and NOR increased by 31.7% and 2.8%, respectively, compared with the original sample. The infrared spectrum and elemental analysis results showed that the morphology of the OM changed, suggesting that the structure of the OM contributes substantially to the adsorption of antibiotics. The contribution of OM to NOR adsorption was greater than that of TC. In conclusion, the results verify the importance of OM in adsorbing antibiotics onto SPM, which may provide basic data for antibiotic migration in surface water.
Smart metering and communication interventions reduce significant water leakage by faulty toilets in purpose-built student accommodation
Authors: Zang Jian , Kumar Manish , Werner David 
Published: June 2023

Abstract
Water efficiency is a global sustainability challenge encapsulated in the United Nation’s Sustainable Development Goal 6 (SDG6), target 6.4. We used building level smart metering to investigate low endpoint water use efficiency in purpose-built student accommodation blocks, a rapidly growing residence type in the United Kingdom. Baseflow accounted for up to 42% of the annual water demand in three accommodation blocks housing 240 students at Newcastle University. Audits identified faulty, continuously running toilets as the main reason for these high baseflows. Each faulty toilet wasted between 4,800 to 12,000 litres per day of potable water, equivalent to the baseflow corrected water use of between 47 and 106 students. The median payback period for recovering the cost of toilet repairs via reduced water bills was 2.9 days, less than the median 6-day period of water wastage before a faulty toilet was identified and repaired. Management, maintenance and cleaning staff, and student occupant engagements reduced baseflows in Windsor Terrace from 4,577 cubic meters in the calendar year 2017 to 2,453 cubic meters in the calendar year 2019. These water savings amounted to an annual water bill saving of £4,023, five times higher than the £828 annual smart metering costs. We conclude that rapid identification and repair of faulty appliances supported by smart metering is a cost effective and sustainable water efficiency strategy. With timely repairs of faulty appliances, significant water savings can be achieved without up-front investment into additional infrastructures such as water storage tanks and pipes, which have embedded environmental impacts.
Biochar-layered double hydroxide composites for the adsorption of tetracycline from water. Synthesis, Process Modeling and Mechanism
Authors: Zubair Mukarram , Manzar Mohammad Saood , El-Qanni Amjad , Haroon Hajira , Alqahtani Hissah A. , Al-Ejji Maryam , Mu’azu Nuhu Dalhat , AlGhamdi Jwaher M. , Haladu Shamsuddeen A. , Al-Hashim Dana , Ahmed Syed Z. 
Published: June 2023

Abstract
In this study, the MgFeCa layered double hydroxides was supported in biochar (B) using co-precipitation, hydrothermal, and co-pyrolysis methods. The prepared B-MgFeCa composites were investigated for tetracycline (TC) adsorption from an aqueous solution. The B-MgFeCa composites synthesized through co-precipitation and hydrothermal methods exhibited better crystallinity, functional groups, and well-developed LDH structure within the biochar matrix. However, the co-pyrolysis method resulted in the LDH structure breakage, leading to the low crystalline composite material. The maximum adsorption of TC onto all B-MgFeCa was obtained at an acidic pH range (4-5). The B-MgFeCa composites produced via hydrothermal and co-pyrolysis methods showed higher and faster TC adsorption than the co-precipitation method. The kinetic results can be better described by Langmuir kinetic and mixed order models at low and high TC concentrations, indicating that the rate-limiting step is mainly associated with active binding sites adsorption. The Sip and Freundlich models showed better fitting with the equilibrium data. The TC removal by B-MgFeCa composites prepared via hydrothermal and co-pyrolysis was mainly dominated by physical and chemical interactions. The composite obtained via the co-precipitation method adsorbed TC through chemical bonding between surface functional groups with anionic species of TC molecule. The B-MgFeCa composite showed excellent reusability performance for upto five cycles with only 30% decrease in TC removal efficiency. The results demonstrated that B-MgFeCa composites could be used as promsing sorbent material for effective wastewater treatment.
Caveolin-1 mediates the utilization of extracellular proteins for survival in refractory gastric cancer
Authors: Hwang Nahee , Yoon Bo Kyung , Chun Kyu-Hye , Kim Hyeonhui , Lee Yoseob , Kim Jae-Won , Jeon Hyeonuk , Kim Tae-Hyun , Kim Mi-Young , Fang Sungsoon , Cheong Jae-Ho , Kim Jae-woo 
Published: June 2023

Abstract
Despite advances in cancer therapy, the clinical outcome of patients with gastric cancer remains poor largely due to tumor heterogeneity. Thus, finding a hidden vulnerability of clinically refractory subtypes of gastric cancer is crucial. Here, we report that chemo-resistant gastric cancer cells heavily rely on endocytosis, facilitated by caveolin-1, for survival. caveolin-1 was highly up-regulated in the most malignant SEM (stem-like, EMT, and mesenchymal)-type gastric cancer cells, allowing caveolin-1-mediated endocytosis and utilization of extracellular proteins via lysosomal degradation. Down-regulation of caveolin-1 alone was sufficient to induce cell death in SEM-type gastric cancer cells, emphasizing its importance as a survival mechanism. Consistently, chloroquine, the lysosomal inhibitor, successfully blocked caveolin-1-mediated endocytosis, leading to the marked suppression of tumor growth in chemo-refractory gastric cancer cells in vitro including patient-derived organoids, and in vivo. Together, our findings suggest that caveolin-1-mediated endocytosis is a key metabolic pathway for gastric cancer survival and a potential therapeutic target.
Association between anion gap and all-cause mortality of critically ill surgical patients: a retrospective cohort study
Authors: Sun Xu , Lu Jianhong , Weng Wenqian , Yan Qiang 
Published: June 2023

Abstract
Background
There are few widely accepted and operationally feasible models for predicting the mortality risk of patients in surgical intensive care unit (SICU). Although serum anion gap (AG) is known to be correlated with severe metabolic acidosis, no investigations have been reported about the association between AG level and the outcome during hospitalization in SICU. This study aimed to explore the predictive power of AG for 90-day all-cause mortality in SICU.
Methords:
Data of the eligible patients in SICU from 2008 to 2019 was obtained from the Medical Information Mart for Intensive Care IV version 2.0 (MIMIC-IV v2.0) database. Baseline clinical data of the selected patients was compared in different groups stratified by the outcome during their addmission via univariate analysis. Restricted cubic spline (RCS) was drawn to confirm the relationship of AG and the short-term mortality. Kaplan-Meier survival curve was plotted in different AG level groups. Univariate and multivariate Cox analyses were performed, and Cox proportional-hazards models were built to investigate an independent role of AG to predict 90-day all-cause mortality risk in SICU.
Results
A total of 6395 patients were enrolled in this study and the 90-day all-cause mortality rate was 18.17%. Univariate analysis showed that elevated serum AG was associated with higher mortality (P < 0.001). RCS analysis indicated a positively linear relationship between serum AG and the risk of 90-day all-cause mortality in SICU (χ2 = 4.430, P = 0.218). Kaplan-Meier survival analysis demonstrated that low-AG group (with a cutoff value of 14.10 mmol/L) had a significantly higher cumulative survival rate than the counterpart of high-AG group (χ2 = 96.370, P < 0.001). Cox proportional-hazards models were constructed and confirmed the independent predictive role of AG in 90-day all-cause mortality risk in SICU after adjusting for 21 confounding factors gradually (HR 1.490, 1.305–1.701, P < 0.001). In the further subgroup analyses, a significant interaction was confirmed between AG and sepsis on the risk for the 90-day mortality.
Conclusions
Elevated AG (≥ 14.10 mmol/L) is an independent risk factor for predicting sever conditions and poor prognosis of critical ill surgical patients.
The association between 8-OHdG levels and diabetic neuropathy patients from sensory functioning and neurological symptoms
Authors: Shi Hong , Han Li , Fu Xu , He Jirui , Song Li 
Published: June 2023

Abstract
Objective
This clinical study aims to evaluate the association between the levels of urine 8-hydroxy-2-deoxyguanosine (8-OHdG) and neuropathic symptoms and nervous sensory signs in patients with diabetic peripheral neuropathy (DPN).
Methods
A total of 81 individuals with DPN participated in this clinical investigation. According to patients’ symptoms, the nerve conduction studies (NCS), the neuropathy symptom scores (NSS) and their neuropathy deficit scores (NDS) category, four symptom clusters were allocated: no symptoms, mild symptoms, moderate symptoms, and severe symptoms. The four neurological function categories were defined as no signs, mild signs, moderate signs and severe signs. We used an enzyme-linked immunosorbent assay kit to measure the levels of urine 8-OHdG. All statistical tests were performed using the Statistical Package for the Social Sciences, version 25.0 (IBM-SPSS, Chicago, IL, USA).
Results
Based on the results of the ordinary logistic regression, it can be concluded that neuropathic sensory function deficits were not related to neuropathic symptoms in patients with DPN; age was associated with neuropathic function deficits of the left and right feet in DPN patients; and the level of urine 8-OHdG was correlated with neuropathic symptoms in patients with DPN.
Conclusions
In this clinical study, it can be deduced that neuropathic sensory function was not linked with neuropathic symptoms in diabetic neuropathy patients. We identified that the clinical parameters of age were associated with the development of neuropathic function deficits and that the level of urine 8-OHdG was related to the development of neuropathic symptoms in patients with DPN.
Diversity and Assemblage of Mangroves Along the Carigara Bay in Leyte, Philippines
Authors: Decena Syrus Cesar , Avorque Carlo , Macasait Dionesio , Arribado Arwin 
Published: June 2023

Abstract

The paper presents a detailed ecological investigation of mangroves (trees and palm) along Carigara Bay in Leyte, Philippines by comparing the diversity, vegetation structure, species composition, and indicator species among forest types (riverine and fringe) and zones (landward, middleward, and seaward/along water) as well as by examining their relationships with environmental variables. A total of 22 mangrove species, belonging to 12 families were documented wherein the most abundant was Sonneratia alba, followed by Nypa fruticans, then by Avicennia rumphiana. It was found that the diversity (Shannon-Wiener) of riverine mangroves (0.94 ± 0.07; 1.20 ± 0.04) was significantly higher than the fringe for both in the middleward and seaward/along the water. In the fringe mangrove forests, the mangrove species Aegiceras corniculatum was associated with the middleward zone, and Camptostemon philippinensis, Aegiceras floridum, Rhizophora mucronata, Sonneratia alba, and Lumnitzera littorea were associated with the seaward zone, whereas landward zone of fringe and all the zones in riverine were generally associated by species with low to optimum salt tolerances such as Nypa fruticans, and Avicennia rumphiana as the most abundant. As well, a total of 14 mangroves have been identified as indicator species. Lastly, mangrove species can be generally classified as riverine and fringing based on the environmental factors explaining their distributions, and it has been found that soil porosity, water content, soil salinity, and distance from the sea or river’s edge were the most significant environmental factors that determine diversity patterns.
Understanding Non-Transport Decision Theories in the Pre-hospital Setting: A Comprehensive Narrative Review
Authors: Farhat Hassan , Laughton James , Aifa Kawther El , Nashwan Abdulqadir , Gangaram Padarath , Khadhraoui Moncef , Gargouri Imed , Alinier Guillaume 
Published: June 2023

Abstract

Background: Pre-hospital emergency calls do not always result in the patient being transported to the hospital. Such decisions can jeopardize healthcare outcomes and lead to wasting resources.
Objectives and Methods: The purpose of this review was to summarize the various theories reported in the literature regarding patient non-conveyance to healthcare facilities in the pre-hospital emergency setting. Studies published between January 2012 and August 2022 were identified from PubMed and Google Scholar. These studies were subsequently screened using the AL-Rayyan® software.
Results and Discussion: Twenty-nine articles that summarized patient non-transport theories were identified. Patient non-transport is a crucial health issue. The factors related to the non-transport were: patient-initiated refusals (PIR), clinical-initiated decisions (CID), and dispatcher-initiated decisions (DID).
Conclusions: Patient non-transport to hospitals remains a serious challenge for emergency care systems. Hence, it requires greater attention from different healthcare systems. Further analysis is necessary to understand pre-hospital non-transport events and identify improvement areas. This approach helps prevent the wastage of resources while ensuring that patients receive the appropriate and definitive care they require.
EEG Signal Based Multi Class Emotion Recognition using Hybrid 1D-CNN and GRU
Authors: Gupta Harshil , Sharma Ojesh , Bhardwaj Dhruv , Yadav Jyoti , Singh Inderjeet 
Published: June 2023

Abstract
In this study, a hybrid architecture combining a Convolutional Neural Network (1D-CNN) and Gated Recurrent Unit (GRU) is proposed for multi-class emotion recognition using EEG signals.Emotion recognition using EEG signals is a challenging task due to the ever-changing nature of EEG signals and the high dimensionality of the feature space. The proposed approach aims to address these challenges by utilizing a hybrid architecture that combines the strengths of both 1D-CNN and GRU. The 1D-CNN is used to retrieve relevant spatial features from the EEG signals, while the GRU is employed to capture the temporal dependencies in the signals. The models were used to classify multi-class emotions: four and sixteen emotions based on the valence-arousal and valence-arousal-liking-dominance planes, respectively, using the benchmark DEAP dataset. The experiment results showed that the proposed models achieved high accuracy in classifying emotions for both four and sixteen emotions as compared to state of art methods. The results of this research have significant implications for the development of affective computing systems in various fields, including healthcare, human-computer interaction, and education. In conclusion, this study demonstrates the potential of deep learning models in affective computing and provides a foundation for future research in this field. The use of reliable physiological signals and the combination of different architectures have shown to be effective in accurately classifying emotions.
Investigating the phenology and interactions of competitive plant species co-occurring with invasive Lantana camara in Indian Himalayan Region.
Authors: Kumar Abhishek , Singh Sanjay , Kumar Dinesh , Singh Ram Kumar , Gupta Ajay Kumar , Premkumar Kangujam , Chand Harish Bahadur , Kewat Anil Kumar 
Published: June 2023

Abstract
Invasive plant species are considered one of the significant drivers of habitat loss for endangered plants by strangling and covering native flora in various biogeographical zones. They have also been observed to alter the local ecology, resulting in a decline in the frequency and abundance of native inhabitants that the invaded region supports. The settlement of aggressively spreading invasive species is widely recognized as one of the most severe challenges to biodiversity conservation. Lantana camara is an invasive that affects the local biodiversity and is considered one of the ten worst weeds by the International Union for Conservation of Nature (IUCN). Native and indigenous species may evolve to compete with invasive species, reducing invader fitness. It is observed that species competition fluctuates throughout environmental gradients, life phases, and abundances. Hence competition outcome is very context-dependent.In the present study, we conducted field surveys in Doon Valley of the Indian Himalayan Region (IHR) to screen the species growing and competing with Lantana camara. We identified the potential competitor species based on the Domin-Karajin scale and IVI. In our experiments, we observed phenological growth patterns (using the BBCH scale) for these species with Lantana and conducted experiments for intra and interspecific competition using RII (Relative Interaction Index). We suggest native species that can potentially reduce Lantana's invasiveness. The present study will be helpful for policymakers and park management authorities to adopt the use of competitive native species for dealing with invasives in the IHR.