bluuebunny/crossref_metadata_2025_split huggingface dataset:
Emotion Regulation Choice and Psychosis Proneness: A Replication and Extension Study
Authors: Nardelli Carla , Rolland-Carlichi Emma , Bortolon Catherine 
Published: April 2023

Evidence shows that participants choose to disengage during emotion regulation (ER) when facing high intensity stimuli, whereas engage when the intensity is low. No study explored ER choice when participants have more than two strategies to regulate their emotions, nor the role of psychopathology on ER choice. This study aimed to replicate and extend the results of Sheppes et al. (2011) and to explore the role of psychosis-proneness in ER strategies choice. In total, 128 non-clinical participants completed two experimental tasks (a replication task and an extension task), choosing an ER strategy in two conditions. Participants favoured disengagement strategies when the emotional intensity was high and engagement strategies when the intensity was low. Psychosis-proneness seems to be associated with difficulties in adapting to the emotional context. These results expand our understanding on ER choices and provide knowledge on flexibility in ER as well as its implication in psychosis-proneness.
CircPVT1 promotes ER‐positive breast tumorigenesis and drug resistance by targeting ESR1 and MAVS
Authors: Yi Jia , Wang Lei , Hu Guo‐sheng , Zhang Yue‐ying , Du Jiao , Ding Jian‐cheng , Ji Xiang , Shen Hai‐feng , Huang Hai‐hua , Ye Feng , Liu Wen 
Published: April 2023

AbstractThe molecular mechanisms underlying estrogen receptor (ER)‐positive breast carcinogenesis and endocrine therapy resistance remain incompletely understood. Here, we report that circPVT1, a circular RNA generated from the lncRNA PVT1, is highly expressed in ERα‐positive breast cancer cell lines and tumor samples and is functionally important in promoting ERα‐positive breast tumorigenesis and endocrine therapy resistance. CircPVT1 acts as a competing endogenous RNA (ceRNA) to sponge miR‐181a‐2‐3p, promoting the expression of ESR1 and downstream ERα‐target genes and breast cancer cell growth. Furthermore, circPVT1 directly interacts with MAVS protein to disrupt the RIGI–MAVS complex formation, inhibiting type I interferon (IFN) signaling pathway and anti‐tumor immunity. Anti‐sense oligonucleotide (ASO)‐targeting circPVT1 inhibits ERα‐positive breast cancer cell and tumor growth, re‐sensitizing tamoxifen‐resistant ERα‐positive breast cancer cells to tamoxifen treatment. Taken together, our data demonstrated that circPVT1 can work through both ceRNA and protein scaffolding mechanisms to promote cancer. Thus, circPVT1 may serve as a diagnostic biomarker and therapeutic target for ERα‐positive breast cancer in the clinic.
Enhancement of Microalgal Metabolite Production through Euglena sp. Local Strain and Glagah Strain Consortia
Authors: Nur Fatona , Erfianti Tia , Andeska Dea Putri , Egistha Putri Renata Adaranyssa , Nurafifah Istini , Sadewo Brilian Ryan , Suyono Eko Agus 
Published: April 2023

Euglena sp. is green microalgae in an acidic environment (pH 2.5-3.5). Euglena sp. has recently been developed widely in industry because of its capability to produce lipids that can be utilized to synthesize biofuel. Microalgae is a potential source of biodiesel, especially in the form of a consortium culture. One of the microalgae consortium cultures that have been explored is the nature consortium microalgae of Glagah strain. The Glagah consortia were isolated from Lagoon in the Glagah Beach, Kulonprogo, Yogyakarta. This study aimed to determine the total production of biomass, lipids, carbohydrates, and proteins of mixed culture of Glagah strain consortium and Euglena sp. as biodiesel substrate. The biomass test was measured using the dry weigh method using a filtration vacuum pump kit, lipids were measured using the Blight Dryer method by adding chloroform and methanol as solvents, carbohydrates were measured using the Sulfur Phenol Acid method by adding Phenol and sulfuric acid (H2SO4), and proteins were measured using the Bradford method by adding SDS and Bradford’s solution. The total production and productivity of biomass, lipids, carbohydrates, and proteins showed that the mixed culture of Glagah strain consortium with Euglena sp. was higher than the Glagah strain consortium. It reached 0.410 g/L; 0.253; 0.856 g/L; and 0.623 g/L. Therefore, it could be concluded that the mixed culture of the Glagah strain consortium with Euglena sp. could increase the production of biomass, lipids, carbohydrates, and protein up to two times that of the Glagah strain consortium so that this mixed culture treatment could be used as a reference in microalgae cultivation for biodiesel.
Fatores demográficos e clínicos associados à sífilis congênita e gestacional
Authors: Luiz Sartoreto Mafra Adriana , Bernardi Cesarino Claudia 
Published: April 2023

Introdução: A sífilis congênita e gestacional é uma doença infectocontagiosa sistêmica, de notificação compulsória, com evolução crônica e causada pelo Treponema pallidum. O aumento de casos de sífilis em gestante e congênita ocorreu com a ampliação do teste rápido, redução do uso de preservativos e o desabastecimento de penicilina. Objetivos: Identificar, descrever e avaliar os fatores demográficos, clínicos, laboratoriais e tratamento associados aos casos de sífilis em gestante e congênita no Grupo de Vigilância Sanitária GVS XXX - Jales, localizado no noroeste do estado de São Paulo, Brasil, entre 2013 e 2017. Métodos: Estudo descritivo exploratório realizado nos bancos de dados do Sistema de Informação de Agravos de Notificação e Sistema de Informação sobre Nascidos Vivos em que foram analisadas 153 gestantes com sífilis e 55 casos de sífilis congênita. Resultados: Os casos de sífilis em gestantes ocorreram em mulheres jovens de baixa escolaridade e aumentaram de 13 casos em 2013 para 43 casos ,em 2017. A maioria das gestantes realizou teste treponêmico e não treponêmico. O número de parceiros tratados foi superior ao dos não tratados. A incidência de sífilis em gestante foi de 10,37 casos/mil nascidos vivos e a de sífilis congênita foi de 3,73 casos/mil nascidos vivos. Conclusão: Houve um aumento considerável de casos de sífilis em gestante e congênita no período investigado. Os resultados deste estudo demonstram que ainda há muito que evoluir para o alcance da meta da OMS para a eliminação da sífilis como problema de saúde pública.
Therapeutic angiogenesis as an advanced direction for potentiating the angiogenic effect of coronary artery bypass grafting
Authors: Oleynik B. A. , Plechev V. V. , Starodobov V. I. , Evdakov V. A. , Izhbuldin R. I. 
Published: April 2023

Highlights. This review systematizes the results of experimental and clinical studies on the impact of coronary artery bypass grafting on angiogenesis and potential use of pyrimidine derivatives for therapeutic angiogenesis.Abstract. Coronary artery bypass grafting is the preferred treatment modality for multivessel coronary artery disease. However, the clinical efficacy of the procedure decreases over time due to the progression of atherosclerosis in the bypass grafts and native coronary arteries. In this regard, it is of great scientific and practical interest to disclose the mechanisms affecting the development of the microvasculature during myocardial surgical revascularization, as well as the search for pharmacological substances capable of stimulating the process of angiogenesis during these surgeries to improve short and long-term outcomes. The article presents a review of experimental and clinical studies on the effect of coronary artery bypass surgery on angiogenesis and highlights the place of pyrimidine derivatives in therapeutic angiogenesis in coronary artery disease.
Coronary-coronary bypass grafting in a child with a stab wound of the anterior interventricular artery
Authors: Podkamenny V. A. , Ivanov E. S. , Batekha V. I. 
Published: April 2023

Highlights. A successful case of surgical treatment of a child with a stab wound of the heart and damaged anterior interventricular artery is presented.Abstract. A girl aged 5 years and 9 months was admitted to the hospital in extremely severe condition with multiple stab wounds to the chest and left shoulder and massive bleeding. The child was immediately taken to the operating room due to hemorrhagic shock and injury localized in the anatomical area directly affecting heart function. The wound in the projection of the interventricular sulcus was repaired with one U-shaped suture, hemodynamics was stabilized by inotropic agents. In the postoperative period, heart failure developed due to akinesia of the apical segments, anterior, lateral and anterolateral walls, and reduced ejection fraction. An emergency coronary angiography revealed an occlusion of the anterior interventricular artery (AIV). Emergency repeated surgical intervention was performed. We diagnosed complete intersection of AIV with thrombosis in the proximal and distal segments. Surgical treatment of the coronary stumps enabled satisfactory antegrade and retrograde blood flow. End-to-end coronary-coronary bypass grafting with AIV grafting was performed on the beating heart. The postoperative period was uneventful. Active lifestyle, absence of complaints, and AIV being opaque, including autogenous graft, were reported in the long-term follow up. The presented case proves that effective diagnostic protocol, echocardiography data and appropriate choice of surgical technique led to a positive outcome.
The influence of orthostatic test (or verticalization) on the blood flow through the internal jugular and vertebral veins
Authors: Shumilina M. V. , Kolesnik D. V. 
Published: April 2023

Highlights. In the absence of venous pathology during verticalization, there is an increase in venous outflow both through the vertebral veins and through the internal jugular veins. In the absence of venous pathology, the internal jugular veins are the dominant route of venous outflow in clinostasis and orthostasis.Aim. To study the dynamics of venous outflow along the internal jugular veins (IJV) and vertebral veins (VV) during the transition from horizontal to vertical position.Methods. The study included 10 healthy women aged 24±2.91 years. Inclusion criteria were as follows: 1) optimal structure of the venous system, in which both of patient`s IJV are approximately symmetrical in cross-sectional area (CSA) and the intensity of the collapse, CSA of IJV exceeds CSA of the common carotid artery by 2–2.5 times, noticeable efficiency of valves during the Valsalva maneuver; 2) venous pressure (VD) in the brachial vein is 18–20 mm Hg. The exclusion criteria were: 1) a history of any disorders of cerebral circulation, symptoms of venous encephalopathy, vertebrobasilar insufficiency, compression of the neurovascular bundle when exiting the chest, arterial hypertension, any cervical spine pathology, hypertrophy and rigidity of the cervical and nodding muscles, 2) arterial pathology of brachiocephalic/intracranial arteries (stenosis, tortuosity, anomalies of the structure), 3) any cardiac pathology, 4) endocrine diseases. The study involved the method of triplex ultrasound with measurements of the cross-sectional areas of IJV, the diameters of VV, time-averaged mean velocity for volumetric blood flow (TAV) in clinostasis and orthostasis. Changes in volumetric venous outflow during verticalization of patients were evaluated as well.Results. In orthostasis, the mean CSA of IJV decreased from 0.862±0.043 cm2 to 0.19±0.024 cm2 , the mean TAV increased from 6.950±2.373 cm/s to 66,000±6.875 cm/s, the average volumetric blood flow increased from 5.952±2.006 mL/s to 12.425±1.559 mL/s. The mean TAV for VV during verticalization increased from 6,800±2.067 cm/s to 16,000±2.271 cm/s, and the average volumetric blood flow from 0.167±0.051 ml/s to 0.402±0.098 mL/s.Conclusion. In all cases, the volumetric blood flow along IJV dominated the volumetric blood flow along VV in clinostasis and orthostasis. In the absence of venous pathology, the dominant pathway of venous outflow in clinostasis and orthostasis are IJV.
Transformation of Risks of Credit Institutions in the Conditions of Digitalization of the Economy
Authors: Филимонова Н.Н. , Слесарева М.Д. 
Published: April 2023

Рассмотрены основные тенденции развития деятельности кредитных организаций в условиях цифровой экономики. Проанализировано влияние пандемии на процесс цифровизации финансового рынка. Выделены основные риски, присущие деятельности кредитных организаций в условиях цифровизации экономики, предложены методы их минимизации.
The article discusses the main trends in the development of credit institutions in the digital economy, analyzes the impact of the pandemic on the process of digitalization of the financial market, highlights the main risks inherent in the activities of credit institutions in the conditions of digitalization of the economy and suggests methods of their minimization.
Innovative Method of Rationale for Choice of the Designer Based on the Risk Tolerance Assessment in Architectural and Construction Design
Authors: Асташенко А.Н. , Бычков А.В. , Давыдянц Д.Е. , Зубов А.О. , Зубова Л.В. 
Published: April 2023

Представлен метод выбора исполнителя на выполнение архитектурно-строительного проектирования на основе риск-ориентированного подхода с использованием показателей предельной стоимости риска, предельного уровня риска, рискоустойчивости и критериев выбора оптимального решения для минимизации потерь.
The article presents an innovative method of selecting a contractor for architectural and construction design based on a risk-oriented approach using indicators of the marginal cost of risk, the maximum level of risk, risk tolerance and criteria for choosing the optimal solution to minimize losses.
The State and Prospects of Digitalization of Legal Practice
Authors: Дорохов Н.И. , Бирюкова Е.А. 
Published: April 2023

Рассматриваются состояние, актуальные проблемы и перспективы развития цифровых технологий в области юридической практики. Анализируется текущее внедрение цифровых сервисов в судебную практику, уточняются первые шаги к цифровизации в системе правосудия в России с 2017 года по настоящее время и выявляются некоторые проблемы, связанные с данным процессом. Проанализированы основные объективные причины медленного темпа перехода к тотальной цифровизации системы правосудия в РФ.
The article focuses on the state, current problems, and prospects for the development of digital technologies in the field of legal practice. The current processes related to the introduction of digital services into judicial practice are analyzed, the first steps towards digitalization in the justice system in Russia from 2017 to the present are specified. The authors reveal some problems associated with this process and analyze the main causes for the slow transition to the total digitalization of the justice system in the Russian Federation.
Perilaku Konsumen Kopi: Proses Keputusan dan Kepuasan Konsumen Membeli Minuman Kopi Berlabel Fair Trade
Authors: Sihombing Vista Uli , Fariyanti Anna , Pambudy Rachmat 
Published: April 2023

Fair Trade (FT) coffee has a higher production volume than other coffee certifications. This phenomenon is triggered by a shift that is influenced consumer behavior patterns. This study analyzes consumer characteristics, purchasing decisions, and satisfaction in buying FT coffee. A cross-sectional study with a quantitative approach was used as the research design. Data were obtained by distributing online questionnaires to 120 respondents using a voluntary sampling technique. Data were analyzed using descriptive analysis, Customer Satisfaction Index (CSI), and Importance Performance Analysis (IPA). The results showed that most respondents were male, with an undergraduate degree and unmarried status. Trends and easy to get drink influence the main reason for purchasing. The main source of information comes from friends who focus on the coffee's taste and flavor. Consumers will continue to buy coffee even though prices have increased. Through CSI calculation, customer satisfaction is worth 74.04%. The results of the IPA calculation show that the main attributes to be improved are price, sales location, and information provision. The results of this study can be used as information on developing a marketing strategy that is adjusted to evaluate consumer expectations.

Keywords: characteristics, consumer behavior, fair trade coffee, purchasing decision, satisfaction
Tarsila ou a vacina antropofágica
Authors: Dias Viviane Costa , Martins Ferdinando 
Published: April 2023

Trata-se de um texto teatral de voz feminista, um diálogo ético e estético com o Modernismo brasileiro na busca de novas imagens para a reinvenção de um país. O texto foi encenado em São Paulo em setembro e outubro de 2022. E segue para Paris, em novembro; E Lisboa, em dezembro do memso ano. Tarsila, um corpo-assentamento do Modernismo brasileiro acorda no cosmos, em 2022. Precisa criar uma nova imagem antes de ser devorada pela voracidade do novo Piaimã.
POTENSI BALITA RISIKO STUNTING DAN HUBUNGANNYA DENGAN KELUARGA PRA-SEJAHTERA DI JAWA TIMUR: ANALISIS DATA PK-21
Authors: Nadhiroh Siti Rahayu , Riyanto Edi Dwi , Jannah Sa'idah Zahrotul , Salsabil Ika Savitri 
Published: April 2023

Jawa Timur merupakan salah satu provinsi di Indonesia dengan prevalensi stunting pada balita tergolong medium. Pemetaan balita berpotensi resiko stunting diperlukan sebagai informasi awal dalam upaya eliminasi stunting. Penelitian ini bertujuan untuk mempelajari potensi balita risiko stunting di Jawa Timur dan menganalisis hubungannya dengan indicator keluarga pra-sejahtera. Penelitian ini menggunakan data sekunder dari Pendataan Keluarga (PK) 2021. Data diperoleh melalui sensus dengan mendata seluruh keluarga yang menjadi target sasaran di Jawa Timur. Pengumpulan data melalui kunjungan rumah menggunakan formulir F/I/PK/21 dan diinput langsung melalui aplikasi berbasis smartphone. Pemetaan Keluarga Sasaran Berpotensi Risiko Stunting dalam penelitian ini menggunakan salah satu penapisan yaitu keluarga pra-sejahtera. Data disajikan secara deskriptif dalam bentuk gambar. Analisis data menggunakan uji korelasi Pearson. Terdapat 11.848.066 kepala keluarga di Jawa Timur yang telah terdata. Jumlah balita potensi risiko stunting terbesar terdapat di Kabupaten Malang, Jember, dan Kota Surabaya. Sedangkan berdasarkan presentase, wilayah dengan balita potensi risiko stunting terbesar adalah Kab. Sampang, Bangkalan, dan Sumenep. Dapat disimpulkan bahwa, balita berpotensi risiko stunting dan keluarga pra-sejahtera di Jawa Timur terkonsentrasi pada Kota/Kabupaten tertentu. Hasil analisis statistic menunjukkan potensi risiko stunting berhubungan dengan keluarga dengan ada anak 7-15 tahun tidak sekolah (p-value<0,001), keluarga dengan tidak ada anggota keluarga yang memiliki sumber penghasilan untuk memenuhi kebutuhan pokok per bulan (p-value=0,001), tidak setiap anggota keluarga makan “makanan beragam” paling sedikit 2 kali sehari (p-value<0,001) serta keluarga pra-sejahtera (p-value<0,001). Diperlukan percepatan pengentasan keluarga pra-sejahtera melalui indicator yang ditetapkan serta peningkatan anggaran dan program percepatan penurunan stunting pada Kabupaten/Kota dengan potensi risiko stunting terbesar.
Pembuatan Protipe Sarana Air Bersih Sebagai Solusi Alternatif Percepatan Penurunan Stunting di Kabupaten Pacitan
Authors: Rahmawati Deti , Soedjono Eddy Setiadi , Soedarso Soedarso , Margini Nastasia Festy , Mukodi Mukodi 
Published: April 2023

Kasus stunting di Kabupaten Pacitan Tahun 2022 mencapai 22,77% angka tersebut merupakan angka yang cukup tinggi dan melampaui ambang batas yang ditetapkan oleh WHO yakn sebanyak 20%. Hasil penelitian kami di Kabupaten Pacitan faktor utama penyebab kasus stunting adalah adanya kemiskinan yang membuat efek domino pada hal lainnya, Minimnya asupan gizi pada anak serta adanya budaya pernikahan dini dibeberapa daerah. Dalam jangka Panjang, stunting berpotensi memperlambat perkembangan otak yang kemudian akan berdampak pada keterbelakangan pertumbuhan baik secara fisik maupun mental. Kondisi stunting sangat erat kaitanya dengan kondisi lingkungan yang tidak sehat seeprti tidak tersedianya sarana air bersih dan sanitasi yang layak. Oleh karena itu, dilakukan upaya untuk menyediakan sarana air bersih di 10 desa lokus stunting melalui program Prototipe sarana air bersih. Program ini dilakukan oleh dosen, mahasiswa, dan masyarakat desa secara swadaya. Pembangunan prototipe sarana air bersih ini diharapkan mampu membuka akses masyarakat terhadap air bersih sehingga angka prevalensi stunting di Pacitan dapat diturukan.
Status Ekonomi Keluarga dan Kecukupan Gizi dengan Kejadian Stunting pada Anak Usia 6-24 Bulan di Kota Surabaya
Authors: Ayuningtyas Hasanah , Nadhiroh Siti Rahayu , Milati Zida Sinata , Fadilah Alfin Lailatul 
Published: April 2023

ABSTRAK
Stunting merupakan masalah gizi kronis yang sering dialami oleh anak di dunia. Kejadian stunting menandai bahwa anak tersebut tidak cukup gizi. Ketidakcukupan gizi merupakan salah satu faktor penyebab stunting yang juga dapat dipengaruhi oleh status sosial ekonomi keluarga. Tujuan penelitian adalah menganalisis hubungan status ekonomi keluarga dan kecukupan gizi dengan stunting pada anak usia 6-24 bulan di Kota Surabaya. Penelitian ini menggunakan desain cross sectional kepada 160 ibu dan anak usia 6-24 bulan yang dipilih menggunakan consecutive sampling di wilayah kerja Puskesmas Tanah Kalikedinding, Putat Jaya, Bangkingan, dan Sememi. Variabel penelitian adalah asupan gizi anak menggunakan recall, pendapatan keluarga dengan kuesioner, serta status gizi yang dikumpulkan dengan pengukuran tinggi badan menggunakan length board atau microtoise. Analisis statistik yang digunakan adalah uji chi square. Penelitian ini menunjukkan bahwa sebagian besar keluarga memiliki pendapatan dibawah UMK kota Surabaya (78,8%). Kecukupan energi pada anak usia 6-24 bulan (50,6%) dan karbohidrat (57,5%) berada pada kategori defisit, kecukupan protein (75,6%) dan lemak (40%) terbanyak berada pada kategori lebih, dan kecukupan zat gizi mikro Fe kurang (51,3%) serta zink (78,1%) dan kalsium (65,6%) dalam kategori cukup. Hasil uji chi square menunjukkan hubungan signifikan antara kecukupan zat besi (p value = 0,021) dan kalsium (p value = 0,000) terhadap kejadian stunting anak usia 6-24 bulan. Kesimpulannya adalah status ekonomi keluarga anak tergolong rendah serta terdapat hubungan antara tingkat kecukupan zat besi dan kalsium pada anak 6-24 bulan di Surabaya dengan kejadian stunting.
Kata kunci— stunting, kecukupan gizi, pendapatan keluarga