bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hydrogen Bonded Dimer of an Alcohol with the Derived Carboxylic Acid Triggering their Sorption by Nanoporous‐crystalline PPO Films
Authors: Nagendra Baku , Cozzolino Antonietta , Acocella Maria Rosaria , Daniel Christophe , Rizzo Paola , Guerra Gaetano 
Published: July 2023

AbstractFilms exhibiting nanoporous‐crystalline (NC) phases of poly(2,6‐dimethyl‐1,4‐phenylene) oxide (PPO), which are highly effective to absorb apolar organic guest molecules, are also able to absorb polar molecules (like alcohols and carboxylic acids) but only from concentrated organic solutions. NC PPO films, which do not absorb alcohols and carboxylic acids from diluted aqueous solutions, exhibits a huge uptake (even above 30 wt %) of benzyl alcohol (BAL) and benzoic acid (BA), if BA is obtained by spontaneous room temperature oxidation of BAL in aqueous solution. This phenomenon is rationalized by an easy uptake, mainly by the PPO intrahelical crystalline empty channels, of a BAL/BA 1/1 hydrogen‐bonded dimer. This huge uptake of BAL/BA dimer by NC PPO films, which is also fast for films exhibiting the orientation of the crystalline helices perpendicular to the film plane (c⊥ orientation), can be exploited for purification of water from BAL, when present in traces. High and fast sorption of a hydrogen bonded dimer and negligible sorption of the two separate compounds is possibly unprecedented for absorbent materials.
Strong Be−N Interaction Induced Complementary Chemical Tuning to Design a Dual‐gated Single Molecule Junction
Authors: Sutradhar Dipankar , Sarmah Amrit , Hobza Pavel , Chandra Asit K. 
Published: July 2023

AbstractThe interaction between pyridines and the π‐hole of BeH2 leads to the formation of strong beryllium‐bonded complexes. Theoretical investigations demonstrate that the Be−N bonding interaction can effectively regulate the electronic current through a molecular junction. The electronic conductance exhibits distinct switching behavior depending on the substituent groups at the para position of pyridine, highlighting the role of Be−N interaction as a potent chemical gate in the proposed device. The complexes exhibit short intermolecular distances ranging from 1.724 to 1.752 Å, emphasizing their strong binding. Detailed analysis of electronic rearrangements and geometric perturbations upon complex formation provides insights into the underlying reasons for the formation of such strong Be−N bonds, with bond strengths varying from −116.25 to −92.96 kJ/mol. Moreover, the influence of chemical substituents on the local electronic transmission of the beryllium‐bonded complex offers valuable insights for the implementation of a secondary chemical gate in single‐molecule devices. This study paves the way for the development of chemically gateable, functional single‐molecule transistors, advancing the design and fabrication of multifunctional single‐molecule devices in the nanoscale regime.
Dissecting the effect of ileal faecal diversion on the intestine using single‐cell sequencing
Authors: Ma Haitao , Li Xiaolong , Pan Yiyang , Wang Liucan , Han Ben , Xie Huichao , Zheng Hong , Jiang Enlai , Chen Jianghong , Li Yunbo , Ji Guangyan , Qiu Yuan , Xiao Weidong 
Published: July 2023

AbstractBackgroundAlthough ileal faecal diversion is commonly used in clinical settings, complications accompany it. Elucidating the intestinal changes caused by ileal faecal diversion will help resolve postoperative complications and elucidate the pathogenic mechanisms of associated intestinal disorders, such as Crohn's disease (CD). Therefore, our study aimed to provide new insights into the effects of ileal faecal diversion on the intestine and the potential mechanisms.MethodsSingle‐cell RNA sequencing was performed on proximal functional and paired distal defunctioned intestinal mucosae from three patients with ileal faecal diversion. We also performed in vitro cellular and animal experiments, tissue staining and analysed public datasets to validate our findings.ResultsWe found that the epithelium in the defunctioned intestine tended to be immature, with defective mechanical and mucous barriers. However, the innate immune barrier in the defunctioned intestine was enhanced. Focusing on the changes in goblet cells, we demonstrated that mechanical stimulation promotes the differentiation and maturation of goblet cells through the TRPA1‐ERK pathway, indicating that the absence of mechanical stimulation may be the main cause of defects in the goblet cells of the defunctioned intestine. Furthermore, we found obvious fibrosis with a pro‐fibrotic microenvironment in the defunctioned intestine and identified that monocytes may be important targets for faecal diversion to alleviate CD.ConclusionsThis study revealed the different transcription landscapes of various cell subsets and the potential underlying mechanisms within the defunctioned intestine, when compared to the functional intestine, based on the background of ileal faecal diversion. These findings provide novel insights for understanding the physiological and pathological roles of the faecal stream in the intestine.
Intelligent deep learning‐aided future beam and proactive handoff prediction model in Unmanned Aerial Vehicle‐assisted anti‐jamming Terahertz communication system
Authors: Unnisa Nazeer , Tatineni Madhavi , Fatima Kaleem , Pasha Mohammad Mahaboob 
Published: July 2023

SummaryWireless communications often suffer from legitimate transmissions regarding malicious jamming attacks launched through the smart jammer. The drone or unmanned aerial vehicle (UAV) communication networks derived with reconfigurable intelligent surfaces (RIS) increase the issues of beam selection and proactive handoff in terahertz (THz). Thus, a new heuristic strategy is designed for efficient and incorporated optimization of the beamforming vector and anti‐jamming transmit power allocation in undefined environments. Here, the transmit power allocation and beamforming matrix of UAV are optimized with the developed hybrid heuristic algorithm of the Hybrid Crow Black Widow Search Optimization (HCBWSO) algorithm for maximizing the system achievable rate. Here, the HCBWSO algorithm is implemented to integrate with the Crow search algorithm (CSO) and Black Widow Optimization (BWO). The second contribution is to adopt RIS into THz–UAV communications, a new Enhanced Deep Temporal Convolutional Network (EDTCN) for predicting the future beam and proactive handoff of UAVs based on their prior analysis of the UAV locations, where the HCBWSO algorithm is utilized for recommending EDTCN. Here, the training of the EDTCN needs to be done with the collection of UAV information from the DEEPMIMO dataset for predicting the future beams and, also, tracking the location of the UAV. EDTCN helps in increasing the possibility of expanding the UAV coverage and also increases the consistency of the THz communication system. Thus, the prediction of the future beam increases the coverage area of the UAV and also maximizes the system rate in the THz communication system.
Integrative systematics and evolutionary history of Berylmys bowersi (Mammalia, Rodentia, Muridae)
Authors: Xu Yifan , Hu Jiangxiao , Shi Zifan , Chen Wenwen , Zhou Jiajun , Zhang Baowei , Yong Fan , Khanal Laxman , Jiang Xuelong , Chen Zhongzheng 
Published: July 2023

AbstractThe Bower's Berylmys (Berylmys bowersi) is one of the largest rodent species with a wide distribution range in southern China and the Indochinese Peninsula. The taxonomy and evolutionary history of the B. bowersi is still controversial and confusing. In this study, we used two mitochondrial (Cyt b and COI) and three nuclear (GHR, IRBP, and RAG1) genes to estimate the phylogeny, divergence times, and biogeographic history of B. bowersi. We also explored morphological variations among the specimens collected across China. Our phylogenetic analyses indicated that the traditional B. bowersi contains at least two species: B. bowersi and B. latouchei. Berylmys latouchei was considered a junior synonym of B. bowersi distributed in eastern China, which is confirmed to be distinguishable at specific level because of its larger size, relatively larger and whiter hind feet, and several cranial traits. The estimated split of B. bowersi and B. latouchei was at the early Pleistocene (ca. 2.00 Mya), which might be the outcome of the combined effects of climate change in the early Pleistocene and isolation by the Minjiang River. Our results highlight the Wuyi Mountains in northern Fujian, China, as a glacial refugia during the Pleistocene and call for more intensive surveys and systematic revisions of small mammals in eastern China.
Beyond Kuhnian paradigms: Normal science and theory dependence in ecology
Authors: Layman Craig A. , Rypel Andrew L. 
Published: July 2023

AbstractThe Structure of Scientific Revolutions by Thomas Kuhn has influenced scientists for decades. It focuses on a progression of science involving periodic, fundamental shifts—revolutions—from one existing paradigm to another. Embedded in this theory is the concept of normal science, that is, scientists work within the confines of established theory, a process often compared to a type of puzzle‐solving. This Kuhnian aspect of scientific research has received little attention relative to the much‐scrutinized concepts of revolutions and paradigms. We use Kuhn's normal science framework to reflect on the way ecologists practice science. This involves a discussion of how theory dependence influences each step of the scientific method, specifically, how past experiences and existing research frameworks guide the way ecologists acquire knowledge. We illustrate these concepts with ecological examples, including food web structure and the biodiversity crisis, emphasizing that the way one views the world influences how that person engages in scientific research. We conclude with a discussion of how Kuhnian ideas inform ecological research at practical levels, such as influences on grant funding allocation, and we make a renewed call for the inclusion of philosophical foundations of ecological principles in pedagogy. By studying the processes and traditions of how science is carried out, ecologists can better direct scientific insight to address the world's most pressing environmental problems.
Cross‐domain state‐of‐health estimation of Li‐ion batteries based on transfer neural network with soft‐dynamic time warping
Authors: Zhang Wenliang , Hu Jingwei , Lin Bing , Liu Dui , Wang Mingfen , Mu Delong , Lu Yu 
Published: July 2023

AbstractThe success of deep learning in the field of state‐of‐health (SOH) estimation relies on a large amount of battery data and the fact that all data possess the same probability distribution. While in real situations, a model based on one working condition data set may not be valid for another working condition data set due to distribution differences. Therefore, this article proposes a transfer learning method using soft‐dynamic time warping (soft‐DTW) as the statistical feature in the feature transfer method, called soft‐DTW domain adaptation network (SDDAN). By combining the prediction error with the time‐series gap in the model training process, the feature transformation can make the obtained prediction results more similar to the source domain results, which can help us to obtain better prediction results in the target domain. Experimental results show that SDDAN can effectively predict the SOH of Li‐ion batteries and significantly improve the performance of feature learning and knowledge transfer.
Survival inequalities in head and neck cancers: A hospital‐based cohort study
Authors: Menezes Fabrício dos Santos , Verzinhasse Peres Stela , de Castro Junior Gilberto , Antunes José Leopoldo Ferreira , Latorre Maria do Rosário Dias de Oliveira , Toporcov Tatiana Natasha 
Published: July 2023

AbstractBackgroundWe investigated whether the socioeconomic status (SES) influenced survival rates in oropharynx cancers (OPC), oral cavity cancers (OCC), and larynx cancers (LC) in Brazilian patients.MethodsThis hospital‐based cohort study assessed the age‐standardized 5‐year relative survival (RS) using the Pohar Perme estimator.ResultsOverall, we identified 37 191 cases, and 5‐year RS were 24.4%, 34.1%, and 44.9% in OPC, OCC, and LC, respectively. In multiple Cox regression, the highest risk of death occurred in the most vulnerable social strata for all subsites—that is, illiterates or patients relying on publicly funded healthcare services. Disparities increased over time by 34.9% in OPC due to the rising of survival rates in the highest SES, whereas they reduced by 10.2% and 29.6% in OCC and LC.ConclusionsThe potential inequities were more significant for OPC than for OCC and LC. It is urgent to tackle social disparities to improve prognoses in highly unequal countries.
Analysis of Goldman Applanation Tonometry with and without fluorescein among glaucomatous and nonglaucomatous patients attending Mzuzu Central Hospital in Malawi: A cross‐sectional study
Authors: Munyapa Tryness , Mzumara Thokozani , Ogbonna Grace , Mvula Augustine 
Published: July 2023

AbstractBackground and AimGoldman Applanation Tonometry (GAT), the gold standard of tonometry, is used without fluorescein in low‐resource settings. Nevertheless, corneal biomechanics differ among population groups.PurposeThe aim of the study is to assess the relationship between GAT findings with and without fluorescein among glaucomatous and nonglaucomatous adults in Malawi.MethodsThis was a cross‐sectional quantitative study involving 22 glaucoma patients and 22 nonglaucoma patients at Mzuzu Central Hospital. We used a purposive sampling technique to select participants into the two groups. Next, we measured intraocular pressure using GAT with and without fluorescein. Then we entered the data into SPSS version 25. We employed the Wilcoxon test to make comparisons based on age and gender. We considered the value of p < 0.05 statistically significant.ResultsThere is a statistically significant and strong positive correlation between nfGAT and fGAT among both glaucoma (r = 0.989, p < 0.001) and nonglaucoma (r = 0.955, p < 0.001). According to age, there is no significant difference in IOP value measured with nfGAT and fGAT for both glaucomas (p = 0.109) and nonglaucoma subjects (p = 0.076). However, significant differences were observed between nfGAT and fGAT mean IOP according to sex among both glaucomatous and nonglaucomatous subjects (p = 0.017 and p = 0.32, respectively).ConclusionThe study suggests that the merits of intraocular pressure measured using GAT without fluorescein are not speculative, therefore the two techniques can be routinely used interchangeably in diagnosing and managing glaucoma.
Spin‐Spin Coupling between the Biradical Moieties in Aromatic Tetraradicals Increases their Reactivity
Authors: Kotha Raghavendhar R. , Yerabolu Ravikiran , Ding Duanchen , Szalwinski Lucas , Nash John J. , Kenttämaa Hilkka I. 
Published: July 2023

AbstractThe reactivity of a carbon‐centered σ,σ,σ,σ‐type singlet tetraradical containing two meta‐benzyne moieties, the 2,4,5,7‐tetradehydroquinolinium cation, was examined in the gas phase toward dimethyl disulfide, cyclohexane and allyl iodide. The major reactions were thiomethyl radical abstraction, H atom abstraction and allyl radical abstraction, respectively. The reactivity of this tetraradical was found to be greater than that of the relevant meta‐benzyne biradicals. The reactivity of individual meta‐benzynes has been found previously to be controlled by their (calculated) distortion energies (ΔE2.30) and singlet‐triplet spittings (ΔES‐T) as well as their electron affinities (EA2.30) at the TS geometry for hydrogen atom abstraction reactions. The addition of another meta‐benzyne moiety to a meta‐benzyne to generate the above tetraradical does not change EA2.30 and only slightly lowers ΔES‐T of both meta‐benzyne moieties. However, ΔE2.30 is significantly decreased for both meta‐benzyne moieties, which explains the higher reactivity of the tetraradical. A similar finding was made previously for an isomeric tetraradical, the 2,4,6,8‐tetradehydroquinolinium cation, that also contains two meta‐benzyne moieties. The decrease in ΔE2.30 is rationalized by a stabilizing coupling between one radical site in each meta‐benzyne moiety for both tetraradicals. Interestingly, the more reactive meta‐benzyne moiety in the two tetraradicals was found to be different: that in the pyridine ring (2,4−) is more reactive for the 2,4,5,7‐tetraradical while that in the benzene ring (6,8−) is more reactive for the 2,4,6,8‐tetraradical. This difference is rationalized by the uniquely small ΔE2.30 value for the 6,8‐moiety in the 2,4,6,8‐tetraradical, which makes this moiety (and this tetraradical) unusually reactive. On the other hand, the ΔE2.30 values for the meta‐benzyne moieties in the 2,4,5,7‐tetraradical are greater and differ only slightly from each other. The slightly greater EA2.30 for the 2,4‐moiety in this tetraradical partially rationalizes the greater reactivity of this moiety when compared to the 5,7‐moiety in the tetraradical.
Identification of novel lncRNA prognostic biomarkers and their associated ceRNAs in bladder urothelial carcinoma
Authors: Lu Sihai , Zhang Xiaobin , Cai Zhiye , Xi Ziyi , Wang Fei , Wang Xuan , Li Wenqi , Dai Penggao 
Published: July 2023

AbstractBladder urothelial carcinoma (BUCA) is a common malignant tumor with a high rate of metastasis and recurrence. The lack of specific and sensitive biomarkers for the prognostic assessment makes it important to seek alternatives. Recent studies have demonstrated that long noncoding RNAs (lncRNAs) function as competitive endogenous RNAs (ceRNAs) and play an important role in BUCA prognosis. Therefore, this study aimed to establish a prognosis‐related lncRNAs–microRNAs (miRNAs)–messenger RNA (mRNA) (pceRNA) network and identify novel prognostic biomarkers. Integrated weighted coexpression analysis, functional clustering, and ceRNA network were used for the prognostic assessment of BUCA. The transcriptome sequencing datasets of lncRNA, miRNA, and mRNA from The Cancer Genome Atlas database were used for the identification of key lncRNAs and construction of the lncRNAs expression signature for prognostic prediction of BUCA patients. Then, 14 differentially expressed lncRNAs (DE‐lncRNAs) were identified as candidate prognostic RNAs based on the ceRNAs network and functional clustering. In the Cox regression analysis, two (AC008676.1 and ADAMTS9‐AS1) of all DE‐lncRNAs were significantly associated with overall survival (OS) of BUCA patients. This two DE‐lncRNA signature was significantly correlated with OS and was an independent prognostic factor, which was confirmed in an independent dataset of GSE216037. Moreover, we constructed the pceRNA network that includes 2 DE‐lncRNAs, 9 DE‐miRNAs, and 10 DE‐mRNAs. Pathway enrichment analysis showed that AC008676.1 and ADAMTS9‐AS1 are involved in several cancer‐related pathways such as proteoglycans in cancer and TGF‐beta signaling pathway. The novel‐identified DE‐lncRNA prognostic signature and the pceRNA network in this study will be valuable risk predictors and diagnostic markers for BUCA.
The application of an intraoral banana peel suturing model in surgical training of dental students
Authors: Liu Ying , Cui Nian‐Hui , Ge Wen‐Shu , Xie Shang , An Na , He Xiao‐Yong , Jiang Yong , Wang Dian‐Can 
Published: July 2023

AbstractObjectivesThis study investigated the application of an intraoral banana peel suturing model in helping students to acquire intraoral surgical techniques.MethodsThis is a self‐control study conducted from January 2021 to March 2021. An intraoral banana peel suturing model was implemented to provide oral suture experience for undergraduates majoring in stomatology. The sutures students placed in the model were photographed and evaluated blindly by a professional team using an established scoring system. Training scores were recorded before (training 1) and after 2 months of training (training 2). Linear regression was used to examine factors related to the scores. Suturing training was conducted in the School and Hospital of Stomatology at Peking University. A total of eighty‐two students in Peking University School and Hospital of Stomatology were in their fourth pre‐clinical year and followed a workshop on surgical sutures according to the curriculum. All students who should take this course were included, and the response rate was 100%.ResultsThe mean training 2 score (23.04 ± 3.83) was higher than the mean training 1 score (13.94 ± 3.15). The training 1 score was not significantly correlated with any of the students' general characteristics. The training 2 score was correlated with the training 1 score and the cumulative duration of practice outside of class.ConclusionThe intraoral banana peel suturing model can be used for suture training, and dental students’ suture ability was improved after using the banana peel for suture practice.
Dental students’ perceptions and educational impact of preclinical interactive videos compared and in combination with live demonstrations
Authors: Tricio Jorge A. , Vicuña Daniela P. , Vicuña Félix P. , Aravena Jaime E. , Naranjo Claudia A. , Orsini César A. 
Published: July 2023

AbstractObjectiveTo study the utility of simulation videos with embedded quiz items compared and in combination with live hands‐on demonstrations of dental procedures.MethodsThirty‐three videos with embedded items were developed to help students understand the procedures they had to practice in the simulation laboratory. Videos were uploaded to the university LMS platform for students to watch and complete the embedded items as many times as they liked. All 76 students from 2021 and 73 from 2022 Integrated Dentistry III courses were invited to participate in the study. Practical (OSCE) and theoretical (MCQ) exam grades of the 2021 academic year, when interactive videos replaced live demonstrations, were collected and compared to those of the previous years (2017–2020) when only live demonstrations were performed, as were those from the 2022 academic year, when videos were complemented with hands‐on live demonstrations. At the end of each year, a perception questionnaire was voluntarily completed by the students.ResultsAssessment grades were significantly higher in the 2021 academic year when interactive videos were incorporated versus the 2017–2020 period when only live demonstrations were performed. However, the combination of interactive videos with live demonstrations performed during 2022 showed the highest exam grades. Seventy‐nine percent of students answered the questionnaire, highly valued the utility of the interactive videos and liked the embedded items. Overall, they stated that they learned from the videos.ConclusionsInteractive videos of preclinical procedures with embedded items combined with live demonstrations can significantly enhance students’ learning and are valued by students.