bluuebunny/crossref_metadata_2025_split huggingface dataset:
High Efficiency Antibacterial, Moisture Permeable, and Low Temperature Comfortable Janus Nanofiber Membranes for High Performance Air Filters and Respiration Monitoring Sensors
Authors: Xia Ming , Yao Zhi , Xiong Ziyin , Wu Yi , Cheng Pan , Cheng Qin , Xu Jia , Wang Xungai , Liu Ke , Wang Dong 
Published: February 2023

AbstractIn this work, high efficiency and multifunctional poly(vinyl alcohol‐co‐ethylene) nanofiber, Ag particle, and polypropylene (PP) meltblown nonwoven substrate composite (NF@Ag) air filters by a simple spray coating method and subsequent UV irradiation treatment are demonstrated. The water vapor transmission rate of the NF@Ag‐4 air filter is 4753.36 ± 316.75 g/(m2 d), which is higher than that of commercial PP nonwoven (4240.71 ± 354.36 g/(m2 d)). It is can be explained that the NF@Ag‐4 air filter is a Janus structure with asymmetric wettability, which enhances moisture permeability, thereby improving comfort while wearing. The NF@Ag‐2 air filter exhibits high filtration efficiency (95.80 ± 0.89%) and relatively low pressure drop (122.00 ± 1.73 Pa) without relying on the electrostatic adsorption effect. The resulting NF@Ag air filters display excellent antibacterial properties against Escherichia coli and Staphylococcus aureus, photothermal disinfection, and thermal insulation performance. Furthermore, the as‐prepared NF@Ag air filters can be simply patterned and designed as respiration monitoring sensors to precisely detect the respiratory activity and health of the human being. Therefore, it is believed that these multifunctional air filters will have good potential for applications in the removal of particular matters and breathable wearable electronic devices.
Electric Field Driven Reversible Spinodal Dewetting of Thin Liquid Films on Slippery Surfaces
Authors: Bhatt Bidisha , Gupta Shivam , Sumathi Vasudevan , Chandran Sivasurender , Khare Krishnacharya 
Published: February 2023

AbstractThe stability of thin liquid films on a surface depends on the excess free energy of the system involving various short‐range and long‐range interactions. When forced to wet an unfavorable surface, thin liquid films dewet into multiple small‐sized droplets via spinodal, homogeneous, or heterogeneous nucleation process. However, if the total excess free energy of the system can be manipulated using external stimuli, for example, electric field, temperature, or light, one can control the stability of thin liquid films on demand. Here the electric‐field induced reversible dewetting and rewetting of thin liquid films underneath aqueous drops on slippery surfaces is studied. Upon applying voltage, hundreds of nanometer thick stable liquid films dewet in a manner identical to the spinodal dewetting of few nanometer‐thick liquid films following the linear stability analysis. Upon removing the applied voltage, the dewetted droplets spread, coalesce with neighboring ones, and form a uniform film again, albeit taking significantly longer times. The characteristic features defined via spatial and temporal evolution of the dewetting and rewetting processes are present over multiple cycles suggesting the complete reversibility of the process.
Biointerface Coatings With Structural and Biochemical Properties Modifications of Biomaterials
Authors: Lee Chin‐Yun , Hu Shu‐Man , Christy Jane , Chou Fang‐Yu , Ramli Theresia Cecylia , Chen Hsien‐Yeh 
Published: February 2023

AbstractDesigning a successful biological interface for a biomaterial requires the application of concepts from multiple fields, including materials science, surface science, nanoscience, physics, and biochemistry. With current biomaterials, such as polymers, ceramics, and natural materials, the original inherent properties of these materials no longer suffice for the needs of advanced and stringent biotechnological and medical applications that require controlled precision of physical and biochemical properties. Thus, the development of surface modifications to provide coatings that alter the interface properties of the original materials is pursued with much success to render desired and sophisticated interfacial properties. With acknowledging the available processing materials and fabrication techniques of the biointerface coatings, perspectives from advanced achievements in both physical and biochemical properties of the coating interfaces, and anisotropic presentations of these properties such as gradient of specific properties, the control of interface properties in confined micro/nanodomains and/or in introduced topographical geometries to mimic relevant biological activities is discussed in depth. The mentioned interface properties and the intended interactions toward biological microenvironments in vitro and in vivo are reviewed. Future prospective biointerface coatings with combinatorial and complementary properties from the discussed disciplines are suggested by the authors’ opinions. Last, challenges of current works demonstrating practical and important applications are discussed.
Flexible Pressure Sensors Based on MXene/PDMS Porous Films
Authors: Wang Zhihua , Xu Zeyu , Li Na , Yao Tao , Ge Manling 
Published: February 2023

AbstractWith the increasing demand for smart devices requires sensors with portability and wearability, high performance and durability,and low cost. In this work, an MXene/PDMS flexible self‐powered porous triboelectric pressure sensor (PTPS) is proposed based on the principles of triboelectrification and electrostatic induction. The film‐forming performance of the sensor is investigated for different MXene hydrosol mass ratios, and three modes of operation and practical performance of the PTPS are studied. The sensor converts the applied mechanical force into electrical signals, and the applied load in the range of 0.15–2.50 N and 2.50–5.15 N has a linear correlation with the output voltage. The obtained results show that the sensor sensitivity in these two ranges is 659.37 and 467.74 mV N−1, respectively. The response time of the proposed PTPS is less than 30 ms, and it can be applied to detect signals with a frequency up to 20 Hz. The voltage output remains stable after 6000 contact–separation test cycles. Moreover, hand gesture recognition, water drop sensing, mouse click, and keyboard press sensing are studied in wearable and non‐wearable scenarios. Based on the obtained results, it is concluded that the proposed PTPS has a promising performance in the field of self‐powered human motion sensing electronics.
How Far for the Electronic Skin: From Multifunctional Material to Advanced Applications
Authors: Chen Yun , Sun Yinglun , Wei Yunyun , Qiu Jianfeng 
Published: February 2023

AbstractElectronic skin that imitates the characteristics and functions of human skin to sense various external signals and records them as different electrical signals has received extensive attention, and much effort has been made on electronic skin for potential medicine application. However, it still needs a long way to achieve practical applications for electronic skin as consumer electronics, the recent progress of electronic skin is reviewed. First, the crucial characteristics in practical electronic skin are analyzed. Subsequently, the technical supports that need to obtain practical electronic skin are also discussed, and electronic skin in terms of short‐term application, medium‐term application and long‐term application are introduced. Finally, suggestions for future development directions in this fascinating field are put forward.
Biomass‐Derived Materials for Interface Engineering in Organic/Perovskite Photovoltaic and Light‐Emitting Devices
Authors: Islam Amjad , Usman Khurram , Haider Zeeshan , Alam Muhammad Fakhar , Nawaz Ali , Sonar Prashant 
Published: February 2023

AbstractCompared to their inorganic counterparts, organic optoelectronic devices receive considerable attention due to their lower cost, mechanical flexibility, bandgap engineering, and solution processability. In particular, achieving sustainability in solar cells and light emitting devices is an important milestone in the development of green electronics. This has facilitated a close collaboration between different technological fields, opening new ways for low‐cost production and application of biomaterials. Recently, biomass materials, mainly derived from plants, animals and microorganisms, have emerged as effective candidates to modify the interfacial properties, and thus enhance the performance, lifetime, and stability of organic solar cells (OSCs), perovskite solar cells (PVSCs), and organic light‐emitting diodes (OLEDs). Compared to the commonly used synthetic interfacial materials, the use of biomass interlayer materials (BIMs) is still in its embryonic stages; however, their nontoxicity, biorelevance, sustainability, special proton conductivity, and rich functional groups are stimulating researchers around the globe to fabricate novel devices with improved efficiency. Herein, a comprehensive review of BIMs and their importance in next‐generation optoelectronic devices is provided. A well‐targeted comparison between the electrical and physical properties of different BIMs is provided, and how such characteristics improve the performance of three key optoelectronic devices: OSCs, PVSCs and OLEDs, is discussed.
Microfluidic Label‐Free Hydrodynamic Separation of Blood Cells: Recent Developments and Future Perspectives
Authors: Lee Sanghyun , Kim Hojin , Yang Sung 
Published: February 2023

AbstractThe biophysical characteristics and counts of blood cells provide useful information regarding pathological conditions. Therefore, the separation of blood components is a crucial task in biology, clinical diagnosis, therapeutics, and personalized medicine. Recently, microfluidics has gained significant interest as an effective technology for separating target cells from heterogeneous cell populations. Within cellular‐scale microchannels, cells of interest are separated based on intrinsic properties, such as size, shape, and deformability, followed by further downstream or off‐chip analysis. In this review, microfluidic‐based hydrodynamic cell‐separation technologies used in label‐free approaches by categorizing them according to their key working principles are discussed: i) flow fractionation, ii) deterministic lateral displacement, iii) hydrophoresis, iv) inertial migration, and v) microfiltration. An overview of the major separation mechanisms is provided, and the relative performances and features of these technologies are thoroughly discussed. In addition, future perspectives regarding microfluidic system commercialization and standardization are briefly provided for their widespread use and applications.
Bioinspired Continuum Robots with Programmable Stiffness by Harnessing Phase Change Materials
Authors: Zhang Jie , Wang Bo , Chen Haohan , Bai Jianing , Wu Zhigang , Liu Ji , Peng Haijun , Wu Jianing 
Published: February 2023

AbstractContinuum robots offer significant advantages over traditional ones in some specific scenarios, such as urban search and rescue, minimally invasive surgery, and inspection of cluttered environments. However, motions and/or operations of existing continuum robots always suffer from those limitations in varying curvature interaction scenarios because of the homogeneity and singleness of the structural stiffness. Herein, inspired by the mechanism of an elephant trunk for regulating local stiffness, a three‐segment continuum robot constructed by tensegrity structure, which relies on a stiffness tunable material, with its Young's modulus switchable between 1.79 and 271.62 MPa to achieve the robotic stiffness programmable characteristics, is proposed. For predicting the robotic configuration with varying stiffness distribution, a mechanical model based on the framework of the finite element method is derived. Theoretical predictions reveal that the curvature of each segment can be regulated by programming stiffness of the smart materials; therefore, the customizable design can offer an effective route for real‐time robotic interactions. By evaluating motion characteristics, stiffness performance, and conformal interaction capability, the experimental results demonstrate that the robot can freely regulate the configuration on‐demand, which may provide a foundation for the application of continuum robots with programmable stiffness for interacting with unstructured environments.
3D‐Printed Anisotropic Nanofiber Composites with Gradual Mechanical Properties
Authors: Lackner Florian , Knechtl Ivan , Novak Maximilian , Nagaraj Chandran , Dobaj Štiglic Andreja , Kargl Rupert , Olschewski Andrea , Stana Kleinschek Karin , Mohan Tamilselvan 
Published: February 2023

Abstract3D printing of bio‐based nanomaterials into complex structures with design flexibility, structural anisotropy, and long‐term stability is a key issue for biomedical applications. Herein, 3D‐printed and ionically crosslinked structures with anisotropic, water‐proof, and tunable mechanical properties are fabricated using a polysaccharide ink composed of nanocellulose, alginate, and CaCO3 nanoparticles. The excellent shear thinning properties of the ink, combined with double or even triple extrusion, allow printing of complex structures (tubes, buckets, ears, and boat models) with high shape fidelity even after crosslinking. The anisotropically printed and crosslinked structures can be mechanically tuned by controlling the fiber orientation via the printing path, the amount of crosslinker, the type of acid used for crosslinking (weak to strong), and the storage medium. This allows for tailored flexibility and a tensile modulus of the materials in wet state ranging from 1 to 30 MPa. Application of hydrostatic pressure of 160–600 mmHg for 24 h with a physiological fluid to a tubular structure, a model for the cardiovascular system, shows no leakage or rupture in the tube. The great design freedom offered by 3D printing and spatially controlled structural anisotropy enable the production of tailored materials for soft robotics or biomedical applications.
Multifunctional Micro/Nanofiber Based‐Dressing Patch with Healing, Protection, and Monitoring Capabilities for Advanced Wound Care
Authors: Ha Ji‐Hwan , Kim Jae Yun , Kim Dahong , Ahn Junseong , Jeong Yongrok , Ko Jiwoo , Hwang Soonhyoung , Jeon Sohee , Jung Young , Gu Jimin , Han Hyeonseok , Choi Jungrak , Lee Gihun , Bok Moonjeong , Park Su A , Cho Yee Sook , Jeong Jun‐Ho , Park Inkyu 
Published: February 2023

AbstractConsiderable efforts have been devoted to developing wound dressings with various functions, including rapid cell proliferation, protection against infection, and wound state monitoring to minimize severe pain and the risks of wound‐caused secondary infections. However, it remains challenging to diagnose wound conditions and achieve integration of the above functions without specialized equipment and expertise in wound care. This study describes an electrospun composite micro/nanofiber‐based bilayer‐dressing patch comprising a healing‐support layer (hyaluronic acid, gelatin, and dexpanthenol) and a protective/monitoring layer (curcumin and polycaprolactone). The improved cell regeneration function and biocompatibility of the healing‐support layer enable rapid healing, as evidenced by the expedited growth of fibroblasts. The superior antimicrobial properties (against Escherichia coli and Staphylococcus aureus) and visible color changes within the pH range of wound lesions (pH 6–9) of the protective/monitoring layer make the dressing suitable for advanced wound care. The wounds inflicted on BALB/c mice heal rapidly (12 days) without scars while the wound state can be diagnosed by the change in color of the dressing patch. The multifunctional wound dressing patch developed in this study is expected to promote wound healing and monitor wound state; thus, facilitating convenient wound management.
Re‐Entrant Microstructures for Robust Liquid Repellent Surfaces
Authors: Vu Hoang Huy , Nguyen Nam‐Trung , Kashaninejad Navid 
Published: February 2023

AbstractSuperhydrophobic surfaces have many interesting applications because of their self‐cleaning, waterproof, anti‐biofouling, anti‐corrosion, and low‐adhesion properties. Accordingly, numerous surfaces with hierarchical micro/nanostructures are designed and engineered to achieve superhydrophobicity. However, these surfaces have two major problems. First, they lose superhydrophobic properties over time, primarily because of environmental conditions such as vibration, external pressure, evaporation, and pollution. Second, most superhydrophobic surfaces fail to repel all types of liquids, especially those with low surface tensions. To address this bottleneck, microstructures with re‐entrant curvature have emerged, demonstrating excellent liquid‐repellent abilities and robustness. Additionally, microstructures with re‐entrant curvature have significant applications in designing surfaces with unidirectional wetting properties for passive liquid handling. Accordingly, this review systematically summarizes the design and fabrication strategies of these re‐entrant microstructures. The emphasis is given to wettability studies and other surface properties of re‐entrant microstructures and their applications, especially for liquid self‐transporting. This paper also highlights the potential applications and remaining technical challenges of fabricating these structures. Finally, the study is concluded by providing the future directions in this promising field.
Mechanistic Insights into the Cycling Behavior of Sulfur Dry‐Film Cathodes
Authors: Fiedler Magdalena , Cangaz Sahin , Hippauf Felix , Dörfler Susanne , Abendroth Thomas , Althues Holger , Kaskel Stefan 
Published: February 2023

AbstractAll‐solid‐state lithium–sulfur batteries (ASSB‐LiS batteries) are considered among advanced candidates for next‐generation energy storage systems, as they break with restrictions and limitations that liquid electrolytes impose on lithium‐ion batteries and lithium‐sulfur batteries (LiS‐batteries), meaning enhanced safety and higher energy densities. However, investigations under realistic conditions on pouch cell level are challenging, as it is necessary to implement a scalable preparation method for sheet‐type cathodes with high sulfur utilization and loading. In this study, a solvent‐free process to prepare free‐standing cathode sheets with low binder content down to 0.1 wt% PTFE is demonstrated. The contribution of binder and electrolyte on the conversion reaction of sulfur is discussed. Sheet‐type cathodes reach nearly theoretical sulfur utilization of 1672 mAh gS−1 and outstanding reversible capacity retention with 72% of initial discharge capacity after 400 cycles by adapting cut‐off voltages to the stability window of the electrolyte. Furthermore, an all‐solid‐state pouch cell is demonstrated using the dry‐film cathode, which is successfully tested for 50 cycles at different C‐rates. Thickness monitoring of the cell stack gives fundamental insights into the volume change and breathing behavior of both cathode and anode.
Establishments and Evaluations of Post‐Operative Adhesion Animal Models
Authors: Wang Yi , Zhai Weijie , Yang Lan , Cheng Shujie , Cui Wenguo , Li Jinghua 
Published: February 2023

AbstractAfter abdominopelvic surgery, there are 90–93% of patients who develop postoperative adhesions. Post‐operative adhesions can occur after various surgical procedures, which not only cause a series of complications but also increase the economic burden of patients. Based on the US FDA rules, anti‐adhesive products need to be deeply evaluated for their bio‐functionality in animal models before clinic entrance. However, to date, there are few literatures systematically summarizing the establish approaches and evaluation standards of various post‐operative adhesion animal models. Therefore, according to the importance of knowledge related to in vivo animal models, in this manuscript, the occurrence mechanism of post‐operative adhesion is systematically reviewed, which is followed by summarizing the construction methods of animal adhesion models at different organs, and then the common evaluation indicators including adhesion scores and histological characterization are listed. This review is a reference to the in vivo characterizations of anti‐adhesive materials.
Fasting: From Physiology to Pathology
Authors: Tang Dongmei , Tang Qiuyan , Huang Wei , Zhang Yuwei , Tian Yan , Fu Xianghui 
Published: February 2023

AbstractOvernutrition is a risk factor for various human diseases, including neurodegenerative diseases, metabolic disorders, and cancers. Therefore, targeting overnutrition represents a simple but attractive strategy for the treatment of these increasing public health threats. Fasting as a dietary intervention for combating overnutrition has been extensively studied. Fasting has been practiced for millennia, but only recently have its roles in the molecular clock, gut microbiome, and tissue homeostasis and function emerged. Fasting can slow aging in most species and protect against various human diseases, including neurodegenerative diseases, metabolic disorders, and cancers. These centuried and unfading adventures and explorations suggest that fasting has the potential to delay aging and help prevent and treat diseases while minimizing side effects caused by chronic dietary interventions. In this review, recent animal and human studies concerning the role and underlying mechanism of fasting in physiology and pathology are summarized, the therapeutic potential of fasting is highlighted, and the combination of pharmacological intervention and fasting is discussed as a new treatment regimen for human diseases.
Targeted Degradation of PRC1 Components, BMI1 and RING1B, via a Novel Protein Complex Degrader Strategy
Authors: Park Kwang‐Su , Qin Lihuai , Kabir Md , Luo Kaixiu , Dale Brandon , Zhong Yue , Kim Arum , Wang Gang Greg , Kaniskan Husnu Ümit , Jin Jian 
Published: February 2023

AbstractPolycomb repressive complex 1 (PRC1) is an essential epigenetic regulator that mainly controls histone H2A Lys119 mono‐ubiquitination (H2AK119ub). B cell‐specific Moloney murine leukemia virus Integration site 1 (BMI1) and really interesting new gene 1B (RING1B) are PRC1 core components and play critical roles in the development of various cancers. However, therapeutic agents targeting PRC1 are very limited. In this study, MS147, the first degrader of PRC1 core components, BMI1 and RING1B, is discovered via a novel protein complex degradation strategy that utilizes the target protein's interacting partner protein (embryonic ectoderm development (EED)). MS147, which comprises an EED small‐molecule binder linked to a ligand of the E3 ligase von Hippel‐Lindau (VHL), degrades BMI1/RING1B in an EED‐, VHL‐, ubiquitination‐, and time‐dependent manner. MS147 preferentially degrades BMI1/RING1B over polycomb repressive complex 2 (PRC2) core components. Consequently, MS147 effectively reduces H2AK119ub, but not histone H3 Lys27 tri‐methylation (H3K27me3), which is catalyzed by PRC2. Furthermore, MS147 effectively inhibits the proliferation of cancer cell lines that are insensitive to PRC2 inhibitors/degraders. Overall, this study provides a novel BMI1/RING1B degrader, which is a useful chemical tool to further investigate the roles of PRC1 in cancer, and a novel protein complex degradation strategy, which can potentially expand the degradable human proteome.