bluuebunny/crossref_metadata_2025_split huggingface dataset:
Altered auditory processes pattern predicts cognitive decline in older adults: different modalities with aging
Authors: Yang Junjie , Tang Xiaochen , Lin Shaohui , Jiang Lijuan , Wei Kai , Cao Xinyi , Wan Lingshan , Wang Jijun , Ding Hansheng , Li Chunbo 
Published: September 2023

BackgroundCohort studies have shown that older adults with hearing impairment as assessed by self-report or behavioral measures are at higher risk of developing dementia many years later. A fine-grained examination of auditory processing holds promise for more effective screening of older adults at risk of cognitive decline. The auditory mismatch negativity (MMN) measure enables one to gain insights into the neurobiological substrate of central auditory processing. We hypothesized that older adults showing compromised indexes of MMN at baseline would exhibit cognitive decline at the one-year follow-up.MethodsWe performed cognitive evaluations with the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS; Form A and Form B) in 108 community-dwelling older adults and acquired EEG via the classic passive auditory oddball paradigm at baseline and 12-month follow-up.ResultsThe results showed that young-old adults with future cognitive decline showed a decrease in MMN peak amplitude, accompanied by a forward-shifting latency, whereas in older adults it showed a delay in MMN latency, and unchanged MMN peak amplitude at midline electrodes (Fz, FCz and Cz). Furthermore, the peak amplitude of the MMN decreases with age in older adults aged 70–80 years rather than 60–70 years or &gt; 80 years.ConclusionThe altered MMN model exists in different aging stages and it’s a promising electrophysiological predictor of cognitive decline in older adults. In addition, further research is needed to determine the neural mechanisms and potential implications of the accelerated decline in MMN in older adults.
Interactive effects of locus coeruleus structure and catecholamine synthesis capacity on cognitive function
Authors: Chen Hsiang-Yu , Parent Jourdan H. , Ciampa Claire J. , Dahl Martin J. , Hämmerer Dorothea , Maass Anne , Winer Joseph R. , Yakupov Renat , Inglis Ben , Betts Matthew J. , Berry Anne S. 
Published: September 2023

BackgroundThe locus coeruleus (LC) produces catecholamines (norepinephrine and dopamine) and is implicated in a broad range of cognitive functions including attention and executive function. Recent advancements in magnetic resonance imaging (MRI) approaches allow for the visualization and quantification of LC structure. Human research focused on the LC has since exploded given the LC’s role in cognition and relevance to current models of psychopathology and neurodegenerative disease. However, it is unclear to what extent LC structure reflects underlying catecholamine function, and how LC structure and neurochemical function are collectively associated with cognitive performance.MethodsA partial least squares correlation (PLSC) analysis was applied to 19 participants’ LC structural MRI measures and catecholamine synthesis capacity measures assessed using [18F]Fluoro-m-tyrosine ([18F]FMT) positron emission tomography (PET).ResultsWe found no direct association between LC-MRI and LC-[18F]FMT measures for rostral, middle, or caudal portions of the LC. We found significant associations between LC neuroimaging measures and neuropsychological performance that were driven by rostral and middle portions of the LC, which is in line with LC cortical projection patterns. Specifically, associations with executive function and processing speed arose from contributions of both LC structure and interactions between LC structure and catecholamine synthesis capacity.ConclusionThese findings leave open the possibility that LC MRI and PET measures contribute unique information and suggest that their conjoint use may increase sensitivity to brain-behavior associations in small samples.
Rapid assessment of malnutrition based on GLIM diagnosis in Crohn’s disease
Authors: Huang Longchang , Niannian Fu , Zhang Yupeng , Shi Yifan , Gao Xuejin , Zhang Li , Wu Yan , Dai Cong , Huang Yuhong , Cao Qian , Zhou Wei , Jiang Haitao , Jing Xue , Zhu Weiming , Wang Xinying 
Published: September 2023

Background and aimsMalnutrition is strongly linked to adverse outcomes in patients with Crohn’s disease (CD). In this study, our objective was to validate the Global Leadership Initiative on Malnutrition (GLIM) criteria and develop a fast and accurate diagnostic approach for identifying malnutrition in CD patients.MethodsThis study assessed 177 CD patients from four general hospitals. The efficacy of the GLIM criteria for the diagnosis of CD malnutrition was compared. By analyzing the independent factors, a nomogram model was derived and internally validated to predict the diagnosis of malnutrition in patients with CD. Model performance was assessed using discrimination and calibration, decision curves, and net benefit analyses.ResultsCompared with the SGA criteria, the GLIM criteria was consistent in sensitivity (88.89%) and specificity (78.43%) [AUC = 0.84; 95% Confidence Interval (CI): 0.77–0.89]. The Harvey-Bradshaw index(HBI) score (OR: 1.58; 95% CI: 1.15–2.18), body mass index (OR: 0.41; 95% CI: 0.27–0.64), and mid-upper arm circumference (OR: 0.68; 95% CI: 0.47–0.9) were independent factors associated with malnutrition. The nomogram was developed based on these indicators showing good discrimination in malnutrition diagnosis (AUC = 0.953; 95% CI: 0.922–0.984), with agreement after calibration curve and decision curve analysis.ConclusionThe GLIM criteria are appropriate for diagnosing malnutrition in CD patients. The HBI score may be used to diagnose malnutrition in patients with CD and become a possible selection for the GLIM etiologic criteria of inflammation. The HBM nomogram could be a simple, rapid, and efficient method for diagnosing malnutrition in CD patients.
Cheong-sang-bang-pung-san alleviated hepatic lipid accumulation by regulating lipid metabolism in vitro and in vivo
Authors: Kang Yun-Mi , Kim Kwang-Youn , Kim Tae In , Kim Yeon-Ji , Kim Han-Hae , Kim Kyungho 
Published: September 2023

Introduction: The occurrence of fatty liver disease, resulting from the accumulation of excessive fat within the liver, has been showing a significant and rapid increase. This study aimed to evaluate the therapeutic effects of Cheong-sang-bang-pung-san extract (CB) on fatty liver disease, and to elucidate the underlying mechanisms.Methods: We used a high-fat diet (HFD)-fed fatty liver mice and free fatty acid (FFA) induced HepG2 cell lipid accumulation model. The levels of serum, hepatic, and intracellular lipid content were assessed. Histopathological staining was used to evaluate the extent of hepatic lipid accumulation. Real-time polymerase chain reaction and Western blotting were conducted to examine the expression of factors associated with lipid metabolism.Results: We demonstrated that treatment with CB dramatically reduced body weight, liver weight, and fat mass, and improved the serum and hepatic lipid profiles in HFD-induced fatty liver mice. Additionally, CB alleviated lipid accumulation in HFD-fed mice by controlling lipid metabolism, including fatty acid uptake, triglyceride and cholesterol synthesis, and fatty acid oxidation, at the mRNA as well as protein levels. In free fatty acid-treated HepG2 cells, CB significantly reduced intracellular lipid accumulation by regulating lipid metabolism via the activation of AMP-activated protein kinase.Conclusion: These findings provide insights into the mechanisms underlying CB’s effects on liver steatosis and position of CB as a potential therapeutic candidate for managing lipid metabolic disorders.
Computational modeling of ventricular-ventricular interactions suggest a role in clinical conditions involving heart failure
Authors: Kim Salla M. , Randall E. Benjamin , Jezek Filip , Beard Daniel A. , Chesler Naomi C. 
Published: September 2023

Introduction: The left (LV) and right (RV) ventricles are linked biologically, hemodynamically, and mechanically, a phenomenon known as ventricular interdependence. While LV function has long been known to impact RV function, the reverse is increasingly being realized to have clinical importance. Investigating ventricular interdependence clinically is challenging given the invasive measurements required, including biventricular catheterization, and confounding factors such as comorbidities, volume status, and other aspects of subject variability.Methods: Computational modeling allows investigation of mechanical and hemodynamic interactions in the absence of these confounding factors. Here, we use a threesegment biventricular heart model and simple circulatory system to investigate ventricular interdependence under conditions of systolic and diastolic dysfunction of the LV and RV in the presence of compensatory volume loading. We use the end-diastolic pressure-volume relationship, end-systolic pressure-volume relationship, Frank Starling curves, and cardiac power output as metrics.Results: The results demonstrate that LV systolic and diastolic dysfunction lead to RV compensation as indicated by increases in RV power. Additionally, RV systolic and diastolic dysfunction lead to impaired LV filling, interpretable as LV stiffening especially with volume loading to maintain systemic pressure.Discussion: These results suggest that a subset of patients with intact LV systolic function and diagnosed to have impaired LV diastolic function, categorized as heart failure with preserved ejection fraction (HFpEF), may in fact have primary RV failure. Application of this computational approach to clinical data sets, especially for HFpEF, may lead to improved diagnosis and treatment strategies and consequently improved outcomes.
Interactive effects of biochar and chemical fertilizer on water and nitrogen dynamics, soil properties and maize yield under different irrigation methods
Authors: Wang Lei , Leghari Shah Jahan , Wu Jiajun , Wang Na , Pang Min , Jin Liang 
Published: September 2023

Long-term application of nitrogen (N) fertilizer adversely degrades soil and decreases crop yield. Biochar amendment with N fertilizer not only can increase yield but also can improve the soil. A 3-year field experiment was conducted to determine the effect of biochar doses with N fertilizer on maize yield and soil N and water dynamics under border irrigation (BI) and drip irrigation (DI) methods. Treatments were 260 kg N ha−1 without biochar addition and combined with low, medium, and high doses of biochar, namely, 15.5 t ha−1, 30.7 t ha−1, and 45.3 t ha−1 (NB0, NB1, NB2, and NB3), respectively. The biochar doses and irrigation methods significantly (p &lt; 0.05) increased maize growth and yield characteristics, irrigation water use efficiency (IWUE), and fertilizer N use efficiency (FNUE) and enhanced the soil properties. In the BI and DI method, the NB1, NB2, and NB3 treatments increased yield by 4.96%–6.10%, 8.36%–9.85%, and 9.65%–11.41%, respectively, compared to NB0. In terms of IWUE and FNUE, the non-biochar treatment had lower IWUE and FNUE compared to biochar combined with N fertilizer treatments under both BI and DI methods. In the BI method, the IWUE in NB2 and NB3 ranged from 3.36 to 3.43 kg kg−1, and in DI, it was maximum, ranging from 5.70 to 5.94 kg kg−1. Similarly, these medium and high doses of biochar increased the FNUE of maize. The FNUEs in NB2 and NB3 under BI ranged from 38.72 to 38.95 kg kg−1 and from 38.89 to 39.58 kg kg−1, while FNUEs of these same treatments under DI ranged from 48.26 to 49.58 kg kg−1 and from 48.92 to 50.28 kg kg−1. The effect of biochar was more obvious in DI as compared to the BI method because soil water content (SWC) and soil N concentrations (SNCs) were higher at rhizosphere soil layers under DI. Biochar improved SWC and SNC at 0–20 cm and 20–40 cm soil layers and decreased below 60-cm soil layers. In contrast, despite biochar-controlled SWC and SNCs, still, values of these parameters were higher in deeper soil layers. In the BI method, the SNCs were higher at 60–80 cm and 80–100 cm compared to the top and middle soil layers. Depth-wise results of SNC demonstrated that the biochar’s ability to store SNC was further enhanced in the DI method. Moreover, biochar increased soil organic matter (OM) and soil aggregate stability and maintained pH. The NB0 treatment increased soil OM by 11.11%–14.60%, NB2 by 14.29%–19.42%, and NB3 by 21.98%–23.78% in both irrigation methods. This increased OM resulted in improved average soil aggregates stability by 2.45%–11.71% and 4.52%–14.66% in the BI and DI method, respectively. The results of our study revealed that combined application of N fertilizer with a medium dose of biochar under the DI method would be the best management practice, which will significantly increase crop yield, improve SWC, enrich SNC and OM, improve soil structure, and maintain pH.
The effect of COVID-19 on the academic performance of Zayed University students in the United Arab Emirates
Authors: AlBlooshi Sharifa , Smail Linda , Albedwawi Alyaa , Al Wahedi Mariam , AlSafi Maha 
Published: September 2023

PurposeThe outbreak of the coronavirus (COVID-19) pandemic led to significant changes across various sectors, including the field of education. In response to the pandemic, educational institutions worldwide, including Zayed University in the United Arab Emirates (UAE), transitioned to online learning. This study aimed to investigate the impact of COVID-19 on the academic performance of students in the UAE and their satisfaction with remote learning, while also examining gender differences in these variables.MethodsThis study used a quantitative research design in which a questionnaire was used to collect data. The study employed a snowball sampling method to recruit a total of 1,780 male and female students aged 18 and above from Zayed University in the UAE. The collected data were analyzed using appropriate statistical techniques.ResultsThis study revealed that students at Zayed University maintained a good level of academic performance (M = 3.34, SD = 0.76) during the COVID-19 pandemic and were satisfied with online learning (M = 3.48, SD = 0.84) during the COVID-19 pandemic. A significant positive correlation was observed between students’ academic performance and their level of satisfaction with online teaching during the COVID-19 pandemic (p &lt; 0.001). Furthermore, no significant differences were found between gender and both academic performance and level of satisfaction with online learning. Finally, we found that more males leaned toward online learning while more females leaned toward face-to-face learning.ConclusionThis study contributes to understanding the impact of COVID-19 on students’ academic performance and satisfaction with remote learning in the UAE context. The findings highlight the significance of student satisfaction for successful online learning and emphasize the need for adequate resources and the maintenance of education quality.
Validation of the Farsi version of the Suicide Ideation and Behavior Scale
Authors: Mehrabi Ali , Naghavi Azam , Afsharzada Mohammad Ershad , Friedrich Sören , Forkmann Thomas , Glaesmer Heide , Teismann Tobias 
Published: September 2023

ObjectiveSuicide ideation and suicide attempts are prevalent in Farsi speaking populations. The present study aimed at validating the Farsi version of the Suicide Ideation and Behavior Scale (SIBS).MethodsReliability and validity of the Farsi version of the SIBS were established in a highly burdened Afghan student sample (N = 279). Internal consistency, convergent and discriminant validity were investigated, and confirmatory factor analysis was conducted.ResultsThe Farsi version of the SIBS was shown to have a unidimensional structure with excellent internal consistency, as well as good convergent and divergent validity.DiscussionThe results suggest that the SIBS is a brief, reliable, and valid measure of current suicidal ideation and behavior that can be used in Farsi speaking populations.
Efficacy of Insecticides against the Invasive Apricot Aphid, Myzus mumecola
Authors: Tabet Dania H. , Visentin Edoardo , Bonadio Martina , Bjeljac Marko , Reyes-Domínguez Yazmid , Gallmetzer Andreas , Spitaler Urban 
Published: September 2023

The invasive apricot aphid (Myzus mumecola Matsumura) is an important pest of apricot trees (Prunus armeniaca L.). In the presented study, laboratory bioassays using treated leaf disks of apricot were conducted to test the efficacy of twelve insecticides according to the maximum field dose. Additionally, dose-response curves were established for selected insecticides, and the effects on colony development were evaluated. Furthermore, a field trial was conducted to investigate the effectiveness of commonly used insecticides in apricot cultivation. The dose-response curves showed LC50 values ranging from 0.08 mg/L for flupyradifurone, 0.15 mg/L for acetamiprid, 0.70 mg/L for etofenprox, 1.89 mg/L for sulfoxaflor, 2.64 mg/L for pirimicarb, 3.97 mg/L for deltamethrin, up to 6.79 mg/L for tau-fluvalinate. These aforementioned insecticides resulted in mortality rates ranging from 95 to 100% at the field dose. Azadirachtin, flonicamid, and pyrethrins showed mortality rates of 27 to 45%. Spirotetramat reduced the colony development and decreased the number of infested shoots by 86%. Spinosad, which is not recommended against aphids, showed minimal impact; reducing the number of exuviae in nymphs in the colony development bioassay. It can be concluded that the majority of the tested insecticides are effective against M. mumecola.
Banquete totêmico e a eucaristia católica
Authors: Monteiro Marcelo Roberto , Marques de Lima Ione 
Published: September 2023

A morte do chamado “pai primevo” por sua própria prole é a alegoria central da obra “Totem e Tabu”, publicada em 1913 por Freud. Nesta obra, tem-se a tese da figura paterna que simbolicamente é destruída brutalmente por seu próprio clã, algo que reverbera fortemente nos aspectos religiosos. Com base nisso, este estudo tem por objetivo discutir sobre as relações que Freud trouxe sobre os rituais religiosos e os povo primitivos, especificamente sobre a eucaristia católica, que é um ritual simbólico em que os fiéis comungam “o corpo e o sangue de Jesus Cristo”, e expiam suas culpas e erros, pedindo redenção por sua morte que, segundo a tradição católica, foi crucificado pelos Judeus. Diante disso, esse ato pode ser visto como um simulacro fiel do parricídio e o prosseguinte “banquete totêmico”, descritos na mencionada obra freudiana.
Perfil epidemiológico de pacientes com fraturas articulares do joelho atendido em hospital terciário na macrorregião da foz do rio Itajaí – SC
Authors: Schueda Marco Antonio , Menegazzo Cristiano Grimm , Bier Rodrigo Schueda , Niada Felipe Guglielmi , De Souza Silas Fernando Pessoa , Mazon Ramon 
Published: September 2023

Objetivo: Realizar levantamento epidemiológico dos pacientes com fraturas articulares de joelho atendidos em Hospital de referência em alta complexidade em Santa Catarina, Sul do Brasil. Métodos: 276 pacientes admitidos com 277 fraturas articulares em joelhos. Avaliados por lado acometido, mecanismo do trauma, classificação da fratura e fraturas concomitantes. Resultados: Mecanismo do trauma mais comum foram os acidentes motociclísticos seguido das quedas de própria altura e de nível. Gênero mais acometido o masculino e o lado direito. Na sequência por maior acometimento das fraturas articulares do joelho temos em porcentagem: Fratura do platô tibial 65,8%; sendo Schatzker I 4,0%; Schatzker II 13,5%; Schatzker III 1,5%; Schatzker IV 5,9%; Schatzker V 28,6%; Schatzker VI 12,3%, seguido por fraturas de patela 19,4%; sendo AO-34A 2,2%; AO-34B 0,4%; AO-34C 16,8%, e fratura do fêmur segmento distal 14,8%; AO-33A 7,3%; AO-33B 3,5%; AO-33C, 4,0%. Existiram fraturas associadas em 27,89% e entre as mais ocorridas encontramos a diafisária do fêmur e clavícula. Conclusão: Acidentes motociclísticos são o mecanismo mais comum com sexo masculino e o lado direito os mais envolvidos. Quando a classificação, as fraturas de platô tibial (Schatzker V) e o terço médio da patela (AO-34C) lideram os atendimentos somando 45,4% dos casos.
Relationships between leaders, capital, and knowledge
Authors: Rzepka Agnieszka 
Published: September 2023

Intellectual capital describes the knowledge resources that a company can use to reap advantages (Muslih, 2021). While human capital is frequently associated with organizational capital (Beltramino, 2020), it is also important to emphasize the role of humans in generating intellectual capital (Dessein& Pratt, 2022; Ozgun, 2022). Interactions between employees within the organization or between its employees and their larger context are crucial. Such relationships have been described as "relational capital" (Zhang, 2022). By one definition, leadership is the ability to influence people to achieve organizational goals (Daft, 2014). There is increasing recognition, however, that traditional leadership models are insufficient to face the challenges of a modern, turbulent world and must be transformed (Brennan, 2022). This article examines the intricate relationship between leaders, capital, and knowledge within a business environment. It uncovers how agile leaders foster a specific atmosphere of creativity and responsiveness while enabling organizations to seize opportunities and confidently tackle challenges. Lastly, it highlights the tangible benefits of an agile leadership approach.
ANALISIS PERBANDINGAN PENDAPATAN USAHATANI PADI (ORYZA SATIVA L) TANAM PINDAH DAN HAMBUR LANGSUNG
Authors: DAHLIANA ANDI BESSE , HASMIDAR HASMIDAR , SUNARSI SUNARSI 
Published: September 2023

The results of field observations in Barebbo Sub-District, the majority of the people are rice business actors using the transplanting planting method and direct seed planting. with a land area of 405 ha which is divided into several strata of land area. Lowland rice farming income using transplanting method and direct seed planting as seen from the use of labor, seeds, costs and farmers' income. The purpose of this study was to find out the comparison of income from rice farming by transplanting parallel rows and direct scattering. This research was carried out for 3 months, from November to January 2022. The number of samples was 40 farmers with a distribution of 20 farmers using the horizontal transplanting system and 20 farmers using the direct scatter seed planting system using the Slovin formula. The technique of determining the sample using purposive sampling method while the research data uses primary data and secondary data. Data analysis used is a type of quantitative data in the form of income analysis. Based on the results of this study, the average income of farmers in transplanting transplanted rice farming is Rp. 25,593,000/ha with an R/C of 2.88, while the average income of farmers in direct scattering rice farming is Rp. 17,993,000/ha with an R /C 2.28 while the average income of farmers in transplanting transplanted rice farming is Rp.16,711,925/ha while the average income of farmers in direct scattering rice farming is Rp.10,484,050/ha.