bluuebunny/crossref_metadata_2025_split huggingface dataset:
Beyond Negative Freedom and the Working Class Subject: Another Kind of Madness
Authors: Cruz Cynthia 
Published: March 2023

Abstract
Presented with the (non) choice of either assimilating into bourgeois society and, thus, annihilating themselves, or being annihilated by society, the working class subject may choose, neither, engaging, instead, in an act of negative freedom. By engaging in an act of negative freedom, the working class subject destroys all possibility of rehabilitation, thus, determining their fate. The act alone provides a means by which to mark the outer limits of what they are willing to tolerate. Through the act, the subject is altered, their world is changed. Furthermore, before engaging in the act, they do not know what will happen to them. They are, in other words, stepping into the abyss of unknowing. In this article, I will explore the concept of negative freedom in relation to the working class subject: how engaging in such an act marks their fate, separating them from bourgeois society while, also, setting them free. At the same time, due to its inherent withdrawal from civil society, negative freedom veers dangerously near nihilism, thus, reducing their act to one without meaning.
The Nexus between Federal Revenue and Spending in Canada: A Time-Frequency Perspective
Authors: Wang Yu , Wei William X. 
Published: March 2023

AbstractThe theoretical literature on the revenue-spending nexus suggests four possible relationships. They are tax-and-spend, negative tax-and-spend, spend-and-tax, and fiscal synchronization. Despite their homogenous research design, the empirical studies of Canada have provided mixed and inconclusive results. This study re-examines the topic from a time-frequency perspective. Specifically, it applies continuous wavelet analysis to the period 1867–2017 to delineate a complete picture of the revenue-spending nexus in Canada. Although results show the existence of all relationships suggested by theory at different time-frequency combinations, the spend-and-tax pattern is the most striking one and dominates the nexus in the long run. Theoretical, methodological, and policy-wise implications of this study are discussed at the end.
Resuscitation dynamics reveal persister partitioning after antibiotic treatment
Authors: Fang Xin , Allison Kyle R 
Published: March 2023

AbstractBacteria can survive antibiotics by forming dormant, drug‐tolerant persisters. Persisters can resuscitate from dormancy after treatment and prolong infections. Resuscitation is thought to occur stochastically, but its transient, single‐cell nature makes it difficult to investigate. We tracked the resuscitation of individual persisters by microscopy after ampicillin treatment and, by characterizing their dynamics, discovered that Escherichia coli and Salmonella enterica persisters resuscitate exponentially rather than stochastically. We demonstrated that the key parameters controlling resuscitation map to the ampicillin concentration during treatment and efflux during resuscitation. Consistently, we observed many persister progeny have structural defects and transcriptional responses indicative of cellular damage, for both β‐lactam and quinolone antibiotics. During resuscitation, damaged persisters partition unevenly, generating both healthy daughter cells and defective ones. This persister partitioning phenomenon was observed in S. enterica, Klebsiella pneumoniae, Pseudomonas aeruginosa, and an E. coli urinary tract infection (UTI) isolate. It was also observed in the standard persister assay and after in situ treatment of a clinical UTI sample. This study reveals novel properties of resuscitation and indicates that persister partitioning may be a survival strategy in bacteria that lack genetic resistance.
The importance of quality management system to certify radioprotection professionals in the medical field
Authors: Luz C. P. V. C. , Delgado J. U. , Sá L. V. , Conceição Dayana D. A. 
Published: March 2023

Certifying professionals in radioprotection (RP), according to the requirements and qualifications established in current Brazilian legislation, ensures that procedures and practices in radiology, radiotherapy and nuclear medicine be performed based on the fundamental principles of radioprotection. However, in none of the regulations and resolutions of the country involving the use of ionizing radiation, the qualification in RP for interventional physicians, radiologists, radiotherapists, nuclear physicians, dentists, nurses and auxiliaries, specialists in medical physics, radiopharmaceuticals, technologists and technicians are clearly defined. It is necessary to adoption a certification scheme through the ABNT NBR ISO/IEC 17024:2013 standard, which will benefit the professionals themselves as well as the patients increasing the safety in RP in the country. This is to the fact that there is no harmony in the regulation of these professionals with the responsible bodies, nor uniformity in practices through international recommendations. This paper proposes the implementation of a quality management system to certify these professionals according to the principles of radiation protection through a survey of needs regarding to the certification of people and the evaluation of systems implemented in other countries.
Egy maszkos üveggyöngy töredéke a Közép-Tisza-vidékről (Szajol-Széle II. lelőhely, Jász-Nagykun-Szolnok vármegye)
Authors: F. Kovács Péter 
Published: March 2023

AbsztraktA La Tène kultúra Kr. e. 4–3. századi elterjedése az Alföldön, annak kapcsolatrendszere és viszonya a helyi, illetve szomszédos kulturális entitásokhoz továbbra is számos kérdést vet fel. Jász-Nagykun-Szolnok vármegyében zajló terepi és kutatói munkának köszönhetően bővülő késő vaskori régészeti leletanyag rendszeres feldolgozásával a korábbi évekhez képest jóval teljesebb képet alkothatunk a korszakban zajló folyamatokról. A Szolnoktól keletre fekvő Szajol település határában végzett terepbejárás és fémkeresőzés során egy maszkos üveggyöngy került elő. A korábban azonosított maszkos gyöngyök elsősorban az Északi-középhegység és az Alföld átmeneti zónájában, a Dunakanyarban, valamint a Felső-Tisza-vidéken kerültek elő. A jelen közleményben bemutatásra kerülő példány mostani ismereteink szerint a legdélebbi elfordulása ennek a tárgytípusnak Magyarország területén.The spread of the La Tène culture during the 4th–3th c. BC in the in the Great Hungarian Plain its system of relations and its relationship with local and neighbouring cultural entities still raises a number of questions. Thanks to the regular field works and researches we can have a more detailed picture of the La Tène period of Jász-Nagykun-Szolnok County. During a field walk and metal detecting a new face-bead shard come to light from east of Szolnok at Szajol-Széle site II. This fragment is probably the most southern occurrence of this time of beads at the moment. From this aspect it is necessary to publish this freshly occurred archaeological find.
Using Delphi method in the development of a modern prostate cancer care quality indicators
Authors: Andreev D. A. , Zavyalov A. A. 
Published: March 2023

Background. Further improvement of the internal quality assurance of clinical practice is critical to achieve the goals and objectives of the Federal project entitled “Battle with cancer”, which aimed at reduction in cancer mortality by 2024 to 185 cases per 100,000 population. Prostate cancer (PCa) is the third leading cause of cancer mortality among men in Russia. For the selection of quality indicators (QIs) for the assessment of oncological care, including the treatment of PCa, the modified Delphi method is widely used.Aim. Identification of examples of actively used modifications of the Delphi technique and the most relevant QIs designed to control the quality of active surveillance of patients with low-risk PCa and the quality of cancer care for patients with metastatic PCa.Materials and methods. The literature search was performed using the following thematic queries in PubMed: “Delphi method/technique”, “quality indicators”, “cancer care”, “prostate cancer”, “tumors”, etc. The search time horizon extended to 2021–2022. The most modern publications devoted to applications of the Delphi methodology in the selection of QIs for treatment of men with PCa were identified.Results. The scientific literature describes in detail how to adapt the Delphi technique to choose the QIs for PCa. 20 QIs for active surveillance of patients with low-risk PCa (the draft version) and 23 QIs for treatment of patients with metastatic PCa were identified. The use of the modified Delphi technique resulted to certain consensus among experts leading to better understanding of QIs for PCa care.Conclusion. The Delphi method is a valid tool for analyzing the points of view of specialists and reaching a consensus on the considered options for solving complex problems. With the consistent improvement of oncourological practice, updating of clinical guidelines for PCa, it is feasible to revise and improve the list of the key QIs for PCa care.
Local cytokine concentration in patients with non-muscle invasive bladder cancer of low malignant potential and with varying rates of recurrence
Authors: Belyakova L. I , Shevchenko A. N. , Shulgina O. G. , Sagakyant A. B. , Burtsev D. V. , Zlatnik E. Yu. , Novikova I. A. , Filatova E. V. , Khvan V. K. , Khomutenko I. A. 
Published: March 2023

Aim. To investigate local concentrations and distribution of cytokines in tumor tissue and perifocal zone in non-muscle invasive bladder cancer of low malignant potential in patients with low and high probability of disease recurrence. Materials and methods. We have studied tumor and perifocal zone fragments of 31 patients with verified non-muscle invasive bladder cancer of low malignant potential and with different probabilities of recurrence. Fifteen (15) patients developed recurrences 6–9 months after combination treatment. The fragments of primary and recurrent tumors were echanically disaggregated and centrifuged at 1500 rpm for 10 minutes. Levels of cytokines interleukin (IL) -1β, -6, -8, -10, -18, tumor necrosis factor α (TNF-α), interferon-γ (Vektor-Best, Russia), and epithelial neutrophil activating peptide 78 (ENA-78) (CXCL-5 chemokine) (Cloud-Clone Corp., USA) were measured in the samples by ELISA. Results were statistically processed using Statistica 13 software (StatSoft Inc., USA), and presented as median and interquartile range – 25th and 75th percentile (Ме [LQ; UQ]).Results. Comparison of cytokine concentrations within the groups showed that the levels of inflammatory cytokines (TNF-α, IL-1β, IL-8, IL-6, IL-18) in tumor tissues were higher than in the perifocal zone tissues. This pattern was expected because tumor is the main site of inflammation. Comparison of these indicators between groups showed that in tumor tissues with an unfavorable course of the disease, namely disease recurrence, the levels of almost all inflammatory cytokines (TNF-α, IL-1β, IL-8, IL-6) were higher. A similar pattern was observed when comparing the levels of cytokines in the tissues of the perifocal zone. These differences were statistically significant. ENA-78 concentration was not determined in all cases.Conclusion. The data obtained during the study indicates that in patients with unfavorable disease course (recurrence), tumor growth is associated with high expression of proinflammatory cytokines, which can subsequently lead to development of disease recurrence.
Trace Elements Reference Values for Soils from Santa Catarina, Brazil
Authors: Marin Suppi Ilana , De Souza Leticia Cristina , Hugen Camila , Miquelluti David Jose , Campos Mari Lucia 
Published: March 2023

The presence of trace elements in the soils, above its natural concentrations, can indicate anthropogenic contamination. Therefore, knowing the natural level of trace elements contents in soils is extremely important in monitoring and remediating contaminated areas. The Brazilian National Environment Council (CONAMA) determines that the states and the Federal District establish the Quality Reference Values (QRV), based on the natural levels of inorganic substances content in soils. Thus, this study aimed to determine the QRV of barium (Ba), cadmium (Cd), nickel (Ni), copper (Cu), zinc (Zn), chromium (Cr), lead (Pb), manganese (Mn) and cobalt (Co) for soils from Santa Catarina. For such, the natural content levels of Cu, Zn, Cr, Pb, Ba, Cd, Ni, Co and Mn were obtained for 43 representative profiles from the state. The natural content and the Quality Reference Values determination for soils from Santa Catarina complied with that requested by the current legislation. The QRV (mg kg-1) was determined based on the 75th percentile (upper quartile) and it was evident, due to the differences among the source materials in SC soils, the need in keeping it by soil groups with similar physical and chemical characteristics, in order to reduce the error possibility in future inspections.
Keywords: Natural Contents. Representative Soils. Environmental Monitoring. Environmental Pollution.

Resumo
A presença de elementos-traço nos solos acima das concentrações naturais pode indicar contaminação antrópica. Sendo assim, o conhecimento dos teores naturais de elementos-traço dos solos é de extrema importância no monitoramento e remediação de áreas contaminadas. O Conselho Nacional de Meio Ambiente (CONAMA) determina que os estados e o Distrito Federal estabeleçam os Valores de Referência de Qualidade (VRQ), baseados nos teores naturais de substâncias inorgânicas nos solos. Dessa forma, este trabalho objetivou determinar os VRQ de bário (Ba), cádmio (Cd), níquel (Ni), cobre (Cu), zinco (Zn), cromo (Cr), chumbo (Pb), manganês (Mn) e cobalto (Co) para solos de Santa Catarina. Para tanto foram utilizados os teores naturais de Cu, Zn, Cr, Pb, Ba, Cd, Ni, Co e Mn obtidos para 43 perfis representativos do estado. Os teores naturais e a determinação dos Valores de Referência de Qualidade para solos de Santa Catarina obedeceram ao preconizado pela legislação vigente. Os VRQ foram determinados com base no percentil 75 (quartil superior) e devido às diferenças entre materiais de origem nos solos de SC, viu-se a necessidade de manter os VRQ por grupo de solos com características físicas e químicas semelhantes, a fim de reduzir a possiblidade de erros em futuras fiscalizações.
Palavras-chave: Teores Naturais. Solos Representativos. Monitoramento Ambiental. Poluição Ambiental.
IMPLEMENTASI PENDIDIKAN KARAKTER (CHARACTER EDUCATION) MELALUI KONSEP TEORI THOMAS LICKONA DI PAUD SEKARWANGI WANASABA
Authors: Astriya Baiq Roni Indira 
Published: March 2023

Tujuan dari penelitian ini adalah untuk mengetahui 1) implementasi pendidikan karakter pada anak usia dini, 2) dampak dari pendidikan karakter pada anak usia dini, 3) kendala yang dihadapi guru dalam proses mengimplementasikan pendidikan karakter pada anak usia dini. Metode penelitian yang digunakan yakni penelitian kualitatif deskriptif, dimana penelitian ini mendeskripsikan data yang diperoleh dari hasil wawancara, observasi, dan dokumentasi. Teknik analisis data yang digunakan berpedoman pada Miles dan Hubermen yang terdiri dari; reduksi data, penyajian data dan verifikasi data. Adapun hasil penelitian ini antara lain: 1) implementasi konsep Thomas Lickona yakni moral knowing merupakan proses pembentukan karakter dengan cara memberikan pengetahuan dan pemahaman yang baik kepada anak melalui pengintegrasian pengetahuan ke dalam proses belajar mengajar, seperti penanaman sikap dan perilaku melalui metode becerita pada setiap kegiatan awal. Sedangkan untuk menumbuhkan aspek moral feeling dapat dilakukan dengan cara membangkitkan kesadaran anak akan pentingnya menjaga komitmen terhadap nilai karakter melalui reward dan punishment, metode pembiasaan, metode karyawisata dengan mengunjungi beberapa tempat di luar sekolah pada setiap puncak tema. Sementara konsep moral action adalah bagaimana membuat pengetahuan moral dapat diwujudkan menjadi tindakan nyata. Dalam hal ini sebanyak 80,76% atau 42 anak dari 52 anak memiliki nilai karakter yang Berkembang Sangat Baik (BSB). 2) Anak sudah mampu membedakan mana yang baik dan tidak baik, menjaga disiplin dalam berbagai kegiatan terprogram, terbiasa melakukan kegiatan rutin, terbiasa menjaga kebersihan diri dan lingkungan. 3) Kendala yang dihadapi guru dalam mengimplementasikan pendidikan yakni aktivitas-aktivitas positif yang biasa dilakukan anak di sekolah terkadang tidak sama dengan apa yang dilakukan di rumah. Solusi yang dilakukan guru ialah memperkuat program parenting dengan melakukan pembentukan koordinator masing-masing kegiatan, dan mengevaluasi program.
The experimental study of the effect of magnetically sensitive elastomers on oil recovery of reservoirs containing high-viscosity oils
Authors:   Azerbaijan State Oil and Industry University, Mustafayeva Rena E. 
Published: March 2023

In world practice, low-viscosity oil accounts for the main share of production. As the development progresses, the share of high-viscosity oil in the total balance increases year on year. The growing unused reserves of high-viscosity oil oblige researchers to solve the issue of developing these reserves, which is an important task for the oil industry. Studies have been carried out to increase oil recovery during the development of oil reservoirs containing high-viscosity oil by pumping a solution of magnetically active polymer, namely silicone oligomer, the matrix of which contains 5–25% Fe+3 ions, treated with a constant transverse magnetic field with a strength of H = 51740 A/m. A mixture of 90% by weight of quartz sand and 10% by weight of bentonite clay, with a permeability of k = 1.4 D, was used as a reservoir model. The high-viscosity oil model consisted of St-45 aviation oil. A silicone oligomer of 159–360 brand was used as a matrix with an operating temperature range of 60°C to +300°C, into which particles of gamma-Fe2O3 Nano powder with a size of 0.5 nm are introduced, with a degree of filling of the matrix of 5–25% by volume of Fe. Magnetization saturation is 80 emu/g, residual magnetization is 460 emu/g, and coercive force is 670 Oh. Validation of the proposed method was carried out by physical modeling of the process of displacement of high-viscosity oil with a magnetic elastomer on a laboratory installation. The oil recovery coefficient was calculated according to a well-known method. The use of magnetically sensitive polymer can be an effective method of developing heavy oil fields. For each heavy oil field, taking into account its specifics (reservoir properties of the rock, physicochemical properties of oil, etc.), an appropriate magnet active polymer is selected. As the experimental results show, the best indicator of the oil recovery coefficient is achieved at 65%, compared with 48% of recovery in the absence of magnetic field exposure.
Apo-B Levels and Abdominal Aortic Wall Thickness in Hypercholesterolemic Rats Treated with Red Guava Fruit
Authors: Maryanto Sugeng , Oktianti Dian 
Published: March 2023

Background: Coronary heart disease (CHD) is mainly related to hypercholesterolemia. Sometimes CHD occurs in people with normal cholesterol. Therefore, it is necessary to study other factors that cause CHD: apolipoprotein B (apo-B). Atherosclerosis is a marker of CHD, characterized by the thickening of the walls of blood vessels and the narrowing of blood vessels. Non-pharmacologically, CHD can be managed by consuming foods with high fiber and antioxidants, such as red guava fruit.
Objectives: This research aimed to analyze the consequence of red guava fruit on the Apo-B levels and the thickness of the abdominal aortic wall in hypercholesterolemic rats.
Methods: The research design was a pre and post-test and a randomized control group. Fifty hypercholesterolemic adults male Sprague Dawley rats were given red guava fruit. The primary treatment used red guava fruit as a treatment group, referring to the fiber requirement of 38 g/day, and simvastatin as a positive control group based on a human dose of 10 mg/day, the conversion of human to mouse dose, according to Laurence-Bacarach is 0.018. The negative control group was hypercholesterolemic rats. The standard feed for the rats was based on AIN93. The Enzyme-linked Immunosorbent Assay method measures apo-B levels, Kit For apo-B Rattus norwegicus, Catalog No. E92003Ra, produced by Uscn Life Science Inc. The aorta was taken after going through general anesthesia and thoracotomy. Furthermore, the aorta was processed for making histological preparations with hematoxylin-eosin (HE) staining to observe histopathological changes.
Results: Observation of aortic wall thickness using a microscope with a magnification of 400X. Simvastatin and red guava fruit have reduced Apo-B by 7% and 6%, respectively.
Conclusions: The performance of red guava fruit in reducing Apo-B concentration and the thickness of the abdominal aortic wall was equal to the simvastatin.
Tinjauan Literatur: Intervensi Suplemen Makanan untuk Meningkatkan Z-Skor PB/U pada Balita Stunting
Authors: Siahaan Maya Fernandya , Rahmatika Auni , Nadhiroh Siti Rahayu 
Published: March 2023

Latar Belakang: Stunting merupakan gangguan pertumbuhan yang berlangsung lama selama pertumbuhan dan perkembangan awal dalam kehidupan. Intervensi untuk mencegah malnutrisi harus dilaksanakan dalam 1000 hari pertama kehidupan. Periode antara usia 6 dan 24 bulan merupakan periode penting karena anak-anak beralih dari ASI eksklusif ke makanan pendamping ASI (MP-ASI).
Tujuan: Tujuan kajian ini untuk memberikan informasi intervensi suplemen makanan yang dapat dipertanggungjawabkan secara ilmiah dalam upaya pencegahan stunting.
Ulasan: Data diperoleh dari kajian berbagai sumber literatur dengan pencarian melalui search engine Google Scholar, BMC, Pubmed, dan Sciencedirect berupa hasil penelitian dalam bentuk jurnal bereputasi dan nasional. Artikel yang didapat berkaitan dengan penelitian ini sebanyak 7 artikel yang berkaitan dengan intervensi suplemen makanan untuk meningkatkan Pb/U Z-skor pada balita stunting umur 6-24 bulan.
Kesimpulan: Terdapat 2 jenis intervensi suplemen makanan yang dilakukan untuk meningkatkan z-skor PB/U pada balita yaitu dengan intervensi zat gizi tunggal (mineral seng) dan kombinasi 2-3 jenis zat gizi (Seng, Besi, Vitamin B12, Vitamin A, Lemak). Sedangkan intervensi kombinasi zat gizi mineral Seng, prebiotik dan suplemen makanan dalam bentuk sachet bubuk mikronutrien tidak menunjukkan perbedaan yang bermakna terhadap pertambahan panjang badan baduta.
A Mixed Clustering Approach for Real Time Anomaly Detection
Authors: Mazarbhuiya Fokrul Alom , Shenify Mohamed 
Published: March 2023

Anomaly Detection in real time data is accepted as a vital research area. Clustering has effectively been tried for this purpose. As the datasets are real time, the time of generating of the data is also important. In this article, we introduce a mixture of partitioning and agglomerative hierarchical approach to detect anomalies from such datasets. It is a two-phase method which follows partitioning approach first and then agglomerative hierarchical approach. The dataset can have mixed attributes. In phase-1, a unified metric defined on mixed attributes is used. The same is also used for merging of similar clusters in phase-2. Also, we have kept the track of time attribute of each data instance which produces the clusters with their lifetimes in phase-1. Then in phase-2, we merge the similar clusters. While merging, the similar clusters, the lifetimes of the corresponding clusters with overlapping cores are to be superimposed producing fuzzy time intervals. This way, each cluster will have an associated fuzzy lifetime. The data instances either belonging sparse clusters or not belonging to any of the clusters can be treated as anomalies. The efficacy of the algorithms can be established using both complexity analysis as well as experimental studies.