bluuebunny/crossref_metadata_2025_split huggingface dataset:
KNOWLEDGE, ATTITUDE, AND PRACTICE (KAP) STUDY ON DENGUE FEVER IN ADULTS: AN ANALYSIS OF 200 PATIENTS
Authors: Iftikhar Mehwash , Khan Imran , Jamal Ayesha , Shah Nazir , Shah Mian Mufarih , Khan Sheraz Jamal 
Published: January 2025

Background: Dengue fever (DF), a viral illness transmitted by mosquitoes, poses a growing public health threat, particularly in tropical and subtropical regions. This study seeks to assess the KAP of 200 adult patients concerning dengue fever in a densely populated urban environment.
Methods: A cross-sectional survey was conducted among 200 adult patients diagnosed with dengue and admitted to the medical units of Hayatabad Medical Complex between January 2023 and December 2023. The data were analyzed using descriptive statistics with SPSS version 26, revealing notable gaps between the patients' knowledge and their preventive behaviors.
Results: Most participants (85%) were aware that dengue is transmitted by mosquitoes, and 78% knew that Aedes aegypti is the main vector. However, fewer recognized key transmission details. Preventive measures were less commonly adopted, with 70% using mosquito repellents or nets, but only 45% eliminating standing water. There was a notable gap between knowledge and practice.
Discussion: The findings show a gap between what people know and what they actually do to prevent dengue. The study highlights the need for better public health efforts, focusing on practical solutions and creating supportive environments to encourage community-wide adoption of preventive measures.
Conclusion: Despite adequate knowledge of dengue transmission and symptoms, preventive practices remain insufficient among adult patients. Public health strategies should focus on bridging this gap through community engagement and government-supported preventive measures.
FREQUENCY OF COMPLETE HEART BLOCK IN PATIENTS PRESENTING WITH INFERIOR WALL MYOCARDIAL INFARCTION
Authors: Hameed Gul  , Ahmad Farooq , Roomana khwajakhail  , Faheem Muhammad , Ashraf Ambar 
Published: January 2025

Objective: To determine the frequency of complete heart block in patients with acute inferior wall myocardial infarction
Methods: Descriptive cross-sectional study conducted in Cardiology Department Khyber Teaching hospital Peshawar from 23 Dec, 2019 to 23 Jun, 2020. Diagnosis of acute inferior wall MI was made. Presence or absence of complete heart block was made with standard 12 lead ECG and continues cardiac monitoring during hospital stay.
Results: A total of 233 patients meeting the inclusion criteria were studied. Mean age ±SD of studied population was 63.86±7.180. Patients were divided into two groups based of age. The number of patients less than 60 years of age were 58 (24.9%) while those 60 years and above were 175 (75.1%). 158 (67.8%) patients were males while 75 (32.2%) patients were females. Complete Heart Block (CHB) was recorded in (18.5%) of patients with Acute Myocardial Infarction (AMI). There was no effect of CV risk factors on CHB except age where elderly patients showed significantly higher rates of CHB
Conclusion: CHB is a common complication in patients with inferior wall myocardial high. Aging increases the risk of CHB in inferior STEMI.
Fault Diagnosis and Optimized Operation and Maintenance of Drop-out Fuses in Alpine Regions Using MKL-SVM and GRU
Authors: Bao Shoujun , Li Shuhong , Pan Ziyong , Liang Fuxiang , Han Shenghai 
Published: January 2025

Extreme climate in alpine regions leads to frequent failures of drop-out fuses, but existing methods have low detection accuracy and response speed. This article combines MKL-SVM (Multiple Kernel Learning-Support Vector Machine) and GRU (Gated Recurrent Unit) model to achieve precise fault diagnosis of drop-out fuses, leveraging their efficient processing of high-dimensional time series data. Sensors are used to collect data such as voltage, current, temperature, and wind speed. Based on GRU, global trends, temporal hidden states, and dynamic nonlinear features of the data are extracted as inputs for subsequent MKL-SVM. In MKL-SVM, a linear kernel function is used to simplify the linear relationship between static features; targeting temporal features, RBF (Radial Basis Function) kernel effectively captures dynamic trends, fluctuations, and periodic changes in temporal features. To further enhance the classification ability of the model, the kernel function parameters, including linear kernel weights and RBF kernel widths, are adjusted through cross-validation. Finally, based on the model diagnosis results and predicted data, an optimized operation and maintenance plan is formulated to reduce maintenance costs and improve equipment operating efficiency. The results show that the fusion model can significantly improve the reliability of fault detection and adapt to the unique environmental challenges of alpine regions. The accuracy of fault diagnosis for drop-out fuses is 95%, with an MSE (mean square error) value of about 0.15 and a maintenance cost reduction of about 21.89%. This method can achieve accurate fault diagnosis and efficient optimization of operation and maintenance under extreme weather conditions.
ANALYSIS OF USAGE ACCEPTANCE OF MOBILE BANKING APPLICATIONS TECHNOLOGY ACCEPTANCE MODEL (TAM) APPROACH
Authors: Sawa Hira , Prayoga Rangga , Sopian Najwar 
Published: January 2025

This research aims to evaluate the factors that influence the behavior of the experience of using the livin application from Bank Mandiri. The approach used is the Technology Acceptance Model (TAM) model developed by Davis in 1989, with a focus on benefits and ease of use, as well as the addition of two external variables, namely security and compatibility. This model was tested empirically using survey data from Livin Application Users from Bank Mandiri. From the results of data analysis obtained during the research, the results show that the use of the Livin application from Bank Mandiri has fulfilled two main aspects in the Technology Acceptance Model (TAM) theory. The Livin application is considered useful for assisting work at Bank Mandiri in the customer service process. From this research it is also known that the use of the Livin Application is not optimal and can still be improved by increasing the benefits of the Liven Application. The Livin application is also easy software, both in terms of installation and modification and easy to use, but efforts are still needed to improve the user's ability to utilize the Livin application.
Frontiers of belonging and politics of identity: the materiality of funeral rituals and festivals in Nigeria’s urban space
Authors: Nnabuihe Onyekachi E. 
Published: July 2023

AbstractThis article draws from funeral rituals and performative festivals to reflect on how and why burials, reburials and performances of Eyo and Nzem Berom festivals provide excellent examples of cultural politics and represent occasions for the (re)production of kinship, belonging and claims to ownership in the cities of Lagos and Jos. It argues that existing literature on the politics of belonging in Africa either understates or overlooks the roles of funerals and festivals in expressing and contesting ownership of the city. Relying on institutional ethnography, the article illustrates the essentially political nature of festivals and funerals in relation to city ownership, not only in the sense that traditional place identity benefits some groups more than others but also in that it defines who belongs and who does not while inducing conflicts.
Intratumoral injection of melatonin enhances tumor regression in cell line-derived and patient-derived xenografts of head and neck cancer by increasing mitochondrial oxidative stress
Authors: Martinez-Ruiz Laura , Florido Javier , Rodriguez-Santana César , López-Rodríguez Alba , Guerra-Librero Ana , Fernández-Gil Beatriz I. , García-Tárraga Patricia , Garcia-Verdugo José Manuel , Oppel Felix , Sudhoff Holger , Sánchez-Porras David , Ten-Steve Amadeo , Fernández-Martínez José , González-García Pilar , Rusanova Iryna , Acuña-Castroviejo Darío , Carriel Víctor S. , Escames Germaine 
Published: July 2023

AbstractHead and neck squamous cell carcinoma present a high mortality rate. Melatonin has been shown to have oncostatic effects in different types of cancers. However, inconsistent results have been reported forin vivoapplications. Consequently, an alternative administration route is needed to improve bioavailability and establish the optimal dosage of melatonin for cancer treatment. On the other hand, the use of patient-derived tumor models has transformed the field of drug research because they reflect the heterogeneity of patient tumor tissues. In the present study, we explore mechanisms for increasing melatonin bioavailability in tumors and investigate its potential as an adjuvant to improve the therapeutic efficacy of cisplatin in the setting of both xenotransplanted cell lines and primary human HNSCC. We analyzed the effect of two different formulations of melatonin administered subcutaneously or intratumorally in Cal-27 and SCC-9 xenografts and in patient-derived xenografts. Melatonin effects on tumor mitochondrial metabolism was also evaluated as well as melatonin actions on tumor cell migration. In contrast to the results obtained with the subcutaneous melatonin, intratumoral injection of melatonin drastically inhibited tumor progression in HNSCC-derived xenografts, as well as in patient-derived xenografts. Interestingly, intratumoral injection of melatonin potentiated CDDP effects, decreasing Cal-27 tumor growth. We demonstrated that melatonin increases ROS production and apoptosis in tumors, targeting mitochondria. Melatonin also reduces migration capacities and metastasis markers. These results illustrate the great clinical potential of intratumoral melatonin treatment and encourage a future clinical trial in cancer patients to establish a proper clinical melatonin treatment.
High-throughput complement component 4 genomic sequence analysis with C4Investigator
Authors: Marin Wesley M. , Augusto Danillo G. , Wade Kristen J. , Hollenbach Jill A. 
Published: July 2023

AbstractThe complement component 4 gene locus, composed of theC4AandC4Bgenes and located on chromosome 6, encodes for C4 protein, a key intermediate in the classical and lectin pathways of the complement system. The complement system is an important modulator of immune system activity and is also involved in the clearance of immune complexes and cellular debris. TheC4gene locus exhibits copy number variation, with each composite gene varying between 0-5 copies per haplotype,C4genes also vary in size depending on the presence of the HERV retrovirus in intron 9, denoted byC4(L)for long-form andC4(S)for short-form, which modulates expression and is found in bothC4AandC4B. Additionally, human blood group antigens Rodgers and Chido are located on the C4 protein, with the Rodger epitope generally found on C4A protein, and the Chido epitope generally found on C4B protein.C4copy number variation has been implicated in numerous autoimmune and pathogenic diseases. Despite the central role of C4 in immune function and regulation, high-throughput genomic sequence analysis ofC4variants has been impeded by the high degree of sequence similarity and complex genetic variation exhibited by these genes. To investigate C4 variation using genomic sequencing data, we have developed a novel bioinformatic pipeline for comprehensive, high-throughput characterization of humanC4sequence from short-read sequencing data, named C4Investigator. Using paired-end targeted or whole genome sequence data as input, C4Investigator determines gene copy number for overallC4, C4A, C4B, C4(Rodger), C4(Ch), C4(L), andC4(S), additionally, C4Ivestigator reports the full overallC4aligned sequence, enabling nucleotide level analysis ofC4. To demonstrate the utility of this workflow we have analyzedC4variation in the 1000 Genomes Project Dataset, showing that theC4genes are highly poly-allelic with many variants that have the potential to impact C4 protein function.
Judicial efficiency and economic growth: Evidence based on European Union data
Authors: Kapopoulos Panayotis , Rizos Anastasios 
Published: July 2023

AbstractWe investigate the effects of judicial efficiency on economic growth using a new dataset over the period 2010–2018 drawn by the European Union Justice Scoreboard. To do so, we estimate a growth equation controlling for alternative de facto judicial efficiency indicators. Our findings suggest that operational inefficiencies of judicial systems undermine economic growth, weakening its capability to safeguard the enforcement of private contracts and the security of property rights. Our results are robust when we account for endogeneity and also provide significant policy implications.
The Legal Framework of Islamic banks
Authors: زيدان محمد فوزي 
Published: July 2023

Islamic banks are among the basic and economic structures on which any country is based, because of the financing they provide for various types of investments and the multiple functions they perform in accordance with the provisions of Islamic Sharia. ahead of traditional banks.
The Islamic Bank came to combine social, economic, financial and banking activities. Perhaps one of the most important features that distinguishes Islamic banks from each other is the degree of effort expended in each of them to investigate the halal profit that can be obtained through the investment process and
to measure this profit in an accurate and clear manner and distribute it in a way that achieves the due justice.
The need for Islamic banks arose as a result of the prosperity of economic and commercial activity in Iraq, which led to the expansion of Islamic banking activity and the emergence of Islamic banks alongside conventional banks.
The Islamic bank is known by several definitions, linguistically and idiomatically, but the Islamic Banking Instructions in Iraq No. 6 of 2011 in force, amended, defined in Paragraph (1) of Article (1) the Islamic Bank as (any legal person who holds a permit or license under these instructions to carry out Islamic banking activities on the According to the provisions of Sharia and does not deal with interest, taking and giving.
Where banks aim to satisfy an existing need or desire, and perhaps one of the most important needs that the Islamic bank spreads is the need of the Islamic community for the existence of an Islamic banking system that works in accordance with the provisions of Islamic Sharia, achieving development and investment goals that it faced through the collection and employment of funds.
Therefore, it is necessary to encourage and turn to Islamic banks and to stay away from traditional banks, as Islamic banks have contributed as an important factor in getting the economy out of the current financial and economic crisis.
We also recommend that the banking institution adopt the opening of a section or the creation of a special division to carry out the work of price fluctuations due to the tremendous development witnessed by the economy at the national and international levels, and it is necessary to expand activities based on banking commission without dealing with interest.
Psychotherapeutic Approach to Borderline Personality Disorder
Authors: Liu Jiayu 
Published: July 2023

Borderline Personality Disorder (BPD) is a psychological disorder largely defined by unstable relationships, identities, and emotions, as well as marked impulsivity. Self-identity disorders, unstable and rapidly changing mental states, significant separation anxiety, conflict in intimate relationships, impulsivity, and stress-related psychiatric symptoms are the most common manifestations. BPD can seriously affect a person's quality of life. Patients with has difficulty recognizing their own identity, and they are often unsure of who they are and have a long-term disorder of their own identity. Moreover, people with BPD have great mood swings, the emotions they feel last longer than the average person, change repeatedly, and it is difficult to stabilize. Therefore, the correct and appropriate treatment is very important for patients with BPD. This paper analyzes the relevant theories about the etiology of BPD and explores the weaknesses and strengths of current treatments under Covid-19. The author first analyzes the theories regarding the etiology of BPD, including the psychopathology of borderline personality disorder, and biological mechanisms. Secondly, the current main treatments of BPD, including dialectical behavior therapy, transference-focused therapy, schema therapy, sandplay therapy, and art therapy are assessed.
PENGARUH MEDIA MASSA TERHADAP PERILAKU PEMILIH PEMULA PADA PEMILU 2024 DI KOTA MATARAM
Authors: Islami Jihadul , Ilham Zitri  
Published: July 2023

Di dalam demokrasi media merupakan sesuatu yang tidak bisa dielakan. Media merupakan agen penting dalam komunikasi dan sosialisasi politik, yang dapat mempengaruhi sikap politik seseorang. Media tentunya dapat memberikan pengaruh terhadap sikap memilih pemilih pemula yang baru pertama kali mengikuti pemilihan umum. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh media terhadap perilaku memilih pemilih pemula pada pemilu kota mataram pada tahun 2024. Pendekatan teori yang digunakan adalah teori uses an gratifications dalam teori komunikasi politik dan teori perilaku memilih. Metode yang digunakan adalah metode Kuantitatif dan Metode analisis data dengan menggunakan Uji Validitas, Uji Realibilitas dan Uji Hipotesis. Responden dalam penelitian ini sebanyak 30 orang yaitu pemilih pemula yang merupakan DPT di Kota Mataram yang tersebar pada 8 kecamatan. Berdasarkan hasil dari analisis dan pembahasan penelitian yang dilakukan bahwa tidak terdapatnya pengaruh dari media terhadap perilaku memlih pada pemilih pemula pemilu di kota mataram dengan variabel Pengamatan, Penilaian, dan Penggunaan Informasi untuk Referensi.
Cytomegalovirus colitis unmasking human immunodeficiency virus infection as a cause of IgA vasculitis
Authors: Bartoletti Alice , Delvino Paolo , Minetto Marco , Milanesi Alessandra , Bozzalla Cassione Emanuele , Quadrelli Verdiana Serena , Luinetti Ombretta , Monti Sara , Montecucco Carlomaurizio 
Published: July 2023

Abstract
Background
Human immunodeficiency virus (HIV) has a protean clinical picture, in rare instances manifesting as systemic autoimmune disorders such as vasculitides. HIV-induced autoimmune diseases often do not respond well to systemic immunosuppressive therapy. Opportunistic infections may occur in patients with either acquired immunodeficiency syndrome (AIDS) or heavy immunosuppressive treatment, and can further complicate the clinical presentation.

Case presentation
A patient presenting with immunoglobulin A (IgA) vasculitis (IgAV) with treatment-refractory purpuric skin rash and suspect intestinal vasculitis was discovered to have AIDS. HIV was the trigger of IgAV, and cytomegalovirus (CMV) colitis mimicked intestinal vasculitis. Antiretroviral treatment improved both CMV colitis and the control of the autoimmune disease.

Conclusions
An autoimmune disease relapsing despite adequate immunosuppressive treatment and/or the presence of recurrent severe opportunistic infections may be clues to an underlying HIV infection.
Yield-related traits and proximate content of winged bean for seed production purpose
Authors: ISHTHIFAIYYAH SAYYIDAH AFRIDATUL , SYUKUR MUHAMAD , TRIKOESOEMANINGTYAS TRIKOESOEMANINGTYAS , MAHARIJAYA AWANG , MARWIYAH SITI 
Published: July 2023

Abstract. Ishthifaiyyah SA, Syukur M, Trikoesoemaningtyas, Maharijaya A, Marwiyah S. 2023. Yield-related traits and proximate content of winged bean for seed production purpose. Biodiversitas 24: 3609-3615. The winged bean is an underutilized plant that can produce valuable seeds with great nutrient content. Meanwhile, the lack of improved genotypes limits its large-scale cultivation. This study aimed to evaluate the flowering and maturity time of winged bean lines and elaborate on various traits correlated with the seed yield. We also performed the seeds' proximate analysis to unravel each line's nutrient content. This study was conducted in Bogor, Indonesia, between April and October 2020. Hybridization between two distinct parents had successfully developed early flowering winged bean genotypes in its progeny. The H4P and L3 had the highest seed yield (1.40 t ha-1) with brown and purple seed colors, respectively. The dried pod weight (0.56), young pod weight (0.36), and the number of dried pods (0.39) had a positive direct effect yet were still smaller than their correlation coefficient. Thus, the selection process to obtain high-yielding winged bean genotypes can be conducted simultaneously through those traits. The evaluated winged bean genotypes had various fat and protein content ranging from 11.10% to 16.48% and 28.81% to 33.45%, respectively. This information can be used as future selection criteria for the winged bean breeding program.
Bioassay-guided isolation of the antioxidant constituent from Kaempferia rotunda L.
Authors: ARYANTINI DYAH , ASTUTI PUJI , YUNIARTI NUNUNG , WAHYUONO SUBAGUS 
Published: July 2023

Abstract. Aryantini D, Astuti P, Yuniarti N, Wahyuono S. 2023. Bioassay-guided isolation of the antioxidant constituent from Kaempferia rotunda L. Biodiversitas 24: 3641-3648. Kaempferia rotunda L. contains various phytochemical compounds with various biological activities and has been widely utilized in traditional medicine. This research focused on exploring bioactive compounds in the ethanol extract of Kaempferia rotunda using radical scavenging (1,1-Diphenyl-2-picrylhydrazyl) bioassay-guided isolation. Initially, the powdered material of K. rotunda was macerated with 70% ethanol and filtered, and the filtrate was evaporated in vacuo to make concentrated ethanol extract. The concentrated ethanol extract was then triturated gradually with increasing polarity of solvents (n-hexane, ethyl acetate, ethanol) to give n-hexane (HSF), ethyl acetate (EASF), ethanol (ESF), and residue (ISF) fractions. Each fraction was tested by DPPH bioassay with quercetin as the positive control to determine the active fraction. The active fraction (ESF) was further fractionated by Vacuum Liquid Chromatography (VLC) using a mobile gradient phase starting from ethyl acetate 100%, acetone 100%, and methanol 100% tomake3 sub-fractions (F1, F2, F3),respectively. The DPPH radical scavenging bioassay showed that F1 was the most active, containing bioactive compound detected by TLC visualized by DPPH. Based on spectroscopic and literature data comparison, this compound was isolated, purified, and identified ascrotepoxide. Crotepoxide displayed IC50of 38.91±0.59 (ABTS), 47.45±0.60 (DPPH),and 26.74±1.23 (FRAP) µg/mL.