bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Profile and Function of Gut Microbiota in Chronic Kidney Disease
Authors: Chen Weihong , Wei Shuwu , Yue Shen , Jiang Wei , Wang Wenna , Teng Fubin , Sun Weiwei , Liu Hongfang 
Published: April 2023

Abstract
Objective:The gut microbiota was considered to be an important hidden "organ" of the human body, which was of great significance in maintaining the body's physiology and pathological regulation. Previous studies had found that the gut microbiota was closely related to various diseases, but there was no unified conclusion on the distribution characteristics of the gut microbiota in chronic kidney disease (CKD) and its relationship with the progression of CKD. In this study, we tried to investigate the profile and function of gut microbiota in CKD and its relationship with the progression of CKD.
Methods: A total of 80 people were enrolled in this study. Twenty were healthy people, and 60 were CKD patients. The CKD patients were divided into three stages including stage 3, 4, and 5. We conducted taxonomic analyses in different groups. The distributions of phyla, classes, orders, families and genera in different groups and samples were investigated. We also evaluated the correlations between clinical parameters and gut microbiota in 60 CKD patients.
Results:The gut microbiota in the healthy group and CKD group had 2351 operational taxonomic units (OTUs) in total. The healthy group had 1076 OTUs, and the CKD group had 2259 OTUs. The diversity of gut microbiota in the stage 3 CKD group was smaller than that in the other groups. Bacteroides was positively correlated with serum creatinine (Scr) and serum cholesterol, while was negatively correlated with albumin (ALB), haemoglobin, and estimated glomerular filtration rate (eGFR). Blautia was positively correlated with Scr, blood urea nitrogen (BUN), 24-hour urine protein (24-h UTP), and serum cholesterol, while was negatively correlated with haemoglobin and eGFR。Bifidobacterium was positively correlated with eGFR, while was negatively correlated with Scr and BUN. Prevotella was negatively correlated with BUN, while was positively correlated with haemoglobin. Megamonas was negatively correlated with BUN, while was positively correlated with haemoglobin and eGFR. Subdoligranulum was negatively correlated with UA. Parabacteroides and megasphaera were positively correlated with serum cholesterol. Klebsiella was negatively correlated with haemoglobin.
Conclusions:The gut microbiota might be one of the important pathological mechanisms underlying the development and progression of CKD. The changes of diversity in gut microbiota were associated with disease progression. Some kinds of gut microbiota including bacteroides, blautia, parabacteroides, megasphaera and klebsiella might be detrimental factors in CKD, while other kinds of gut microbiota including bifidobacterium, prevotella, megamonas and subdoligranulum might be beneficial factors in CKD.
Association of reproductive factors with triple-negative breast cancer and hormone receptor–positive breast cancer among Bangladeshi women
Authors: Islam Muhammad Rafiqul , Zhu Hongxu , Siddiqua Syeda Masuma , Islam Syed Mohammad , Hasan ATM Kamrul , Saha Beauty , Akter Nargis , Khatun Nazrina , Long James P. , Ueno Naoto T. 
Published: April 2023

Abstract
Objective
Despite Bangladesh's high breast cancer prevalence (19.3 cases per 100,000 individuals), data are scarce regarding the reproductive epidemiology of breast cancer in Bangladesh. We investigated whether reproductive factors are associated with hormone receptor–positive breast cancer (Hr + BC) and triple-negative breast cancer (TNBC) in Bangladeshi women.
Methods and Analysis
In a tertiary hospital-based setting, we surveyed 1000 adult Bangladeshi females aged 18 or older. Of which 250 had TNBC, 250 had Hr + BC, and the remaining 500 were non-cancer individuals. Propensity score matching (PSM) was carried out to match the age and age of menarche of the potential 500 healthy individual with 250 TNBC and 250 Hr + BC individuals in separate estimates. The presence of TNBC or Hr + BC was the outcome variable, and the participants’ previous histopathology report confirmed it. We collected participants; detailed reproductive characteristics and demographics through a structured questionnaire. Those significant variables in the bivariate model were finally included in the adjusted multivariate multinomial logistic regression.
Results
The mean ages of participants in the Hr + BC, TNBC, and healthy groups were 44.96, 42.74 and 39.31 years, respectively. Adjusted binary multivariate logistic regression suggested that women living in rural areas with increased number of abortions, experiencing irregular menstruation, and consumption of hormonal contraceptives increased the risk for Hr + BC and TNBC compared to the healthy individuals. However, the magnitude of the risk varies across the types of breast cancer. One year increase in the age of menarche significantly increased the risk for Hr + BC by 1.71 times; however, it decreased the risk for TNBC by 30%.
Conclusion
Our findings imply that women's reproductive factors play a pivotal role in developing Hr + BC and TNBC; however, the degree of risk differs between the different types of breast cancer.
Exploration capacity vs. specific enzymatic activity of ectomycorrhizas in response to primary productivity and soil phosphorus availability in Bornean tropical rainforests
Authors: Okada Kei-ichi , Yokoyama Daiki , Aiba Shin-ichro , Kitayama Kanehiro 
Published: April 2023

Abstract
Aims
Ectomycorrhizal (ECM) fungi are functionally important in biogeochemical cycles in tropical ecosystems. Extracellular enzymatic activity of ECM on a ground-area basis is the product of two attributes; exploring capacity (ECM surface-area) and specific enzymatic activity on an ECM surface-area. Here, we elucidated which attribute better explained the ECM enzymatic activity in response to different levels of soil P and N availability in five Bornean tropical rainforests.
Methods
We determined the surface area of ECM root tips as well as the enzymatic activities per ECM surface area for C, N and P degrading enzymes in each site. We evaluated the relationship of ECM enzyme activities with the resource availabilities of C(ANPP), N, and P of ECM by a generalized linear mixed model.
Results
The ECM enzymatic activities on a ground-area basis were more significantly determined by specific enzymatic activity than by the exploration capacity. Specific enzymatic activities were generally negatively affected by C (ANPP) and soil P availability.
Conclusions
ECM fungi enhance the specific enzyme activity rather than the exploitation capacity to maintain the capacity of nutrient acquisition. The less dependence of ECM fungi on the exploitation capacity in these forests may be related to the limitation of C supply from host trees. We highlighted the adaptive mechanisms of ECM fungi on nutrient acquisition in tropical ecosystems through the response of enzymatic activity to nutrient availability across the elements.
Technologies and Techniques for Measuring the Fluctuation of Lower Limb Residual Volume: A Systematic Review
Authors: Ibrahim Mohd Tajularif , Hashim Nur Afiqah , Razak Nasrul Anuar Abd , Osman Noor Azuan Abu , Gholizadeh Hossein , Astuti Suryani Dyah 
Published: April 2023

Abstract
Increased pressure and shear stress distributions at the limb-socket interface are hypothesised to be resulted from the changes in residual limb shape and volume, which can cause socket fit difficulties. Accurate residual limb volume measurements may aid clinicians in developing strategies to accommodate volume fluctuations. This review primarily aims to analyse the techniques available for measuring the lower limb residual volume as reported in the published works from 1975 until 2021. Comprehensive search of articles in PubMed, ScienceDirect, Web of Science, and Google Scholar identified 904 articles and further analysis resulted in only 39 articles being chosen to be analysed. Based on the findings, there are nine techniques available to measure the residual limb volume, which are water displacement, anthropometric measurement, contact probes, optical scanning, spiral x-ray computed tomography (SXCT), magnetic resonance imaging (MRI), ultrasound, laser scanning, and bioimpedance. Considering the variety of techniques for determining residual limb volume, it's critical to choose the ones that best suit researchers’ objectives, and each technique has potential sources of error which should be avoided by taking precautionary action. A comprehensive study of the measurement technologies is needed since researchers have developed and extensively utilised many new measuring devices especially handheld 3-D laser scanners.
Magnitude and determinants of Substance use among University of Antwerp Students in Belgium: a multilevel analysis approach
Authors: Lakew Asres Zegeye , Hal Guido Van 
Published: April 2023

Abstract
Substance use is one of the public health issues among university students. The study aimed to estimate the prevalence, influence of faculty, and identify possible risk factors for substance use among University of Antwerp students. A cross-sectional study was conducted among University of Antwerp students from March to April 2021. A total of 2769 students participated in the online survey. The outcome variable of interest was measured as recent use of alcohol (non-drinkers, low-risk drinkers, and risky drinker), cannabis use (yes/no), and use of stimulant drugs (yes/no) in the last one year prior to the study. A multilevel generalized linear mixed-effect model was used to analyze the data. Based on the self-reported survey results, the overall prevalence of recent low-risk alcohol use was 68.40%, compared to 21.67% for risky alcohol use, whereas the prevalence of recent cannabis and stimulant drug use was 16.32% and 4.37%, respectively. In the full multivariable generalized linear mixed effect model, being male (OR = 1.77), being a working student (OR = 1.54), lifetime use of cigarettes (OR = 4.07), being a masters student (OR = 1.70), and living independently from parents (OR = 1.71) were identified as risk factors for recent use of alcohol. With regard to recent use of cannabis in the full model, ages between 26 and 30 years (OR = 3.69), master students (OR = 2.02), and following other programs (preparatory and bridging) (OR = 2.52) were determinant factors. Being a master's student was the only individual-level variable associated with lower odds of the recent use of stimulant drugs (OR = 0.40). In the full multivariable model, the proportion change variance for recent alcohol, cannabis, and stimulant drug use was estimated as 83.54, 20.93, and -38.32%, respectively. In addition, the final full model results showed a median odds ratio of 1.11, 1.28, and 3.00 for the recent use of alcohol, cannabis, and stimulant drugs, respectively. The magnitude of alcohol use among University of Antwerp students was found to be high, whereas the use of cannabis and stimulant drugs was moderate and low, respectively. Being male, being over the age of 26 years, working students, pursuing master's and other programs, smoking cigarettes, and living away from parents were risk factors for substance use among students.
Iron deficiency anaemia and its associated factors: A cross-sectional study among children aged 6-23 months in southwestern Uganda
Authors: Dickson kajoba , Egesa Walufu Ivan , Muyombya Solomon , Ortiz Yamile Arias , Nduwimana Martin , Ndeezi Grace 
Published: April 2023

Abstract
Background

Iron deficiency anemia is still a global public health concern with the highest burden among children 6 to 23 months. This is because of their rapid growth spurt exceeding what breastmilk can supply. Therefore, nutritional supply is a key source of iron to attain the required nutrients for better growth and development. The study aimed to determine the prevalence, factors associated, and value of Mentzer index when compared with RDW plus microcytosis in IDA diagnosis among children aged 6 to 23 months in Southwestern Uganda.

Methodology

This was a cross-sectional descriptive study done at Ishaka Adventist Hospital (IAH) and Kampala International University Teaching Hospital (KIUTH) from April to July 2022. Participants were consecutively enrolled in the study. Structured questionnaires, 24-hour dietary recall, and clinical assessment were used to obtain data. Data analysis was done using the statistical package for social scientists (SPSS) V22.0. At univariable analysis, data was summarised using measures of central tendencies. Bivariable and multivariable analysis was done using logistic regression for associations with significance set at P-value < 0.05. The Spearman correlation coefficient was calculated to establish a correlation between the Mentzer index and RDW plus microcytosis.

Results

A total of 364 participants were enrolled, with majority males 198(54.4%) and born at term 333(91.5%). The modal age was 12–17 months [163(44.8%)] with a mean age of 14.1 months (SD 5.32). The overall prevalence of IDA was 151/364 (41.5%). The factors associated with IDA included male sex (aOR 1.61), current episode of diarrhoea (aOR 1.71), poor meal frequency (aOR 1.78), no vegetable consumption (aOR 2.47) and consuming fruits once (aOR 1.97) in 7 days preceding the study. Additionally, the Mentzer index had a strong positive significant correlation with RDW plus microcytosis with a spearman correlation coefficient of 0.521.

Conclusion and recommendation

IDA is highly prevalent among infants 6–23 months with at least four in 10 being affected. Screening for IDA should be recommended in male children with current diarrhea, poor intake of fruits and vegetables, and poor meal frequency. The Mentzer index is an equally good alternative screening test for IDA.
Disparities in healthcare access and utilization among people living with HIV in China: a scoping review and meta-analysis
Authors: Ai Wei , Fan Chengxin , Marley Gifty , Tan Rayner K J , Wu Dan , Ong Jason , Tucker Joseph D. , Fu Gengfeng , Tang Weiming 
Published: April 2023

Abstract
Background
Healthcare disparities hinder the goal of ending the HIV pandemic by 2030. This review aimed to understand the status of healthcare disparities among people living with HIV (PLWH) in China and summarize driving factors.
Methods
We searched six databases: PubMed, Web of Science, Cochrane Library, Scopus, China National Knowledge Infrastructure (CNKI), and China Wanfang. English or Chinese articles published between January 2000 and July 2022 were included if they focused on any disparities in access to and utilization of healthcare among PLWH in China. Grey literature, reviews, conferences, and commentaries were excluded. A random effects model was used to calculate the pooled estimates of data on healthcare access/utilization and identified the driving factors of healthcare disparities based on a socio-ecological framework.
Results
A total of 8728 articles were identified in the initial search. Fifty-one articles met the inclusion criteria. Of these studies, 37 studies reported HIV-focused care, and 14 focused on non-HIV-focused care. PLWH aged ≥ 45 years, female, ethnic minority, and infected with HIV through sexual transmission had a higher rate of receiving antiretroviral therapy (ART). Females living with HIV have higher adherence to ART than males. Notably, 20% (95% CI, 9–43%, I2 = 96%) of PLWH with illness in two weeks did not seek treatment, and 30% (95% CI, 12–74%, I2 = 90%) refused hospitalization when needed. Barriers to HIV-focused care included the lack of knowledge of HIV/ART and treatment side effects at the individual level, and social discrimination and physician-patient relationships at the community/social level. Structural barriers included out-of-pocket medical costs, and distance and transportation issues. The most frequently reported barriers to non-HIV-focused care were financial constraints and the perceived need for medical services at individual-level factors; and discrimination from healthcare providers, distrust of healthcare services at the community/social level.
Conclusion
This review suggests disparities in ART access, adherence, and utilization of non-HIV-focused care among PLWH. Financial issues and social discrimination were prominent reasons for healthcare disparities in PLWH care. Creating a supportive social environment and expanding insurance policies, like covering more medical services and increasing reimbursement rates could be considered to promote healthcare equity.
Investigation of mechanical properties of bamboo fibre reinforced polymer matrix composite for structural applications
Authors: SUTHAR JIGAR , Patel Kaushik , Pandya Divyang 
Published: April 2023

Abstract

Bamboo is an ancient structural material used for a variety of applications in India. Bamboo is widely used in the global south for frames, bridges, housing, and transitory structures. Bamboo supply has been effectively inexpensive as well as plentiful in global south countries to meet the widespread need for affordable housing. The current research focuses on the mechanical properties of bamboo fibre reinforced polymer composite materials for use in structural industries. Moreover, a bamboo fibre reinforced composite was compared to glass fibre in a variety of ways, and it was discovered that the bamboo fibre composite outperformed the glass fibre in a few areas. Investigations revealed the potential use of bamboo fibre reinforced composite with good stiffness but a lower strength limitation than glass fibre composite. Tensile strength of 40.53 MPa and hardness value of 68.2 RHN were achieved by E-glass epoxy composites. However, the results of bamboo fibre reinforced composites cannot be overlooked. Further research was conducted to improve the mechanical properties, and the results were satisfactory.
Chemical tracers of a highly eccentric binary orbit
Authors: Danilovich Taissa , Malfait Jolien , de Sande Marie Van , Montargès Miguel , Kervella Pierre , De Ceuster Frederik , Coenegrachts Arnout , Millar Tom , Richards Anita , Decin Leen , Gottlieb Carl , Pinte Christophe , De Beck Elvire , Price Daniel , Bolte Jan , Menten Karl , Baudry Alain , de Koter Alexander , Etoka Sandra , Gobrecht David , Gray Malcolm , Herpin Fabrice , Jeste Manali , Lagadec Eric , Maes Silke , McDonald Iain , Marinho Louise , Müller Holger , Pimpanuwat Bannawit , Plane John , Sahai Raghvendra , Wallström Sofia , Wong Ka Tat , Yates Jeremy , Zijlstra Albert 
Published: April 2023

Abstract
Binary interactions have been proposed to explain a variety of circumstellar structures seen around evolved stars, including asymptotic giant branch (AGB) stars and planetary nebulae. Studies resolving the circumstellar envelopes of AGB stars have revealed spirals, discs and bipolar outflows, with shaping attributed to interactions with a companion. For the first time, we have used a combined chemical and dynamical analysis to reveal a highly eccentric and long-period orbit for W~Aquilae, a binary system containing an AGB star and a main sequence companion. Our results are based on anisotropic SiN emission, the first detections of NS and SiC towards an S-type star, and density structures observed in the CO emission. These features are all interpreted as having formed during periastron interactions. Our new method can yield stringent constraints on the orbital parameters of long-period binaries containing AGB stars, and establishes a template for future studies.
Improved sine cosine algorithm for optimization problems based on self-adaptive weight and social strategy
Authors: chun Ye , hua Xu 
Published: April 2023

Abstract
The Sine Cosine Algorithm (SCA) is a well-known optimization technique that utilizes sine and cosine functions to identify optimal solutions. Despite its popularity, the SCA has limitations in terms of low diversity, stagnation in local optima, and difficulty in achieving global optimization, particularly in complex large-scale problems. In response, we propose a novel approach named the Improved Weight and Strategy Sine Cosine Algorithm (IWSCA). The IWSCA achieves this by introducing novel self-adaptive weight and social strategies that enable the algorithm to efficiently search for optimal solutions in complex large-scale problems. The performance of the IWSCA is evaluated with 23 benchmark test functions and the IEEE CEC 2019 benchmark suite, compare it to a state-of-the-art heuristic algorithm and two improved versions of the SCA. Our experimental results demonstrate that the IWSCA outperforms existing methods in terms of convergence precision and robustness.
Factors Affecting Capital structure decisions of banks: A Systematic Review Evidence from Commercial banks of Ethiopia
Authors: Gofe Tesfaye Eresso , Seyoum Arega 
Published: April 2023

Abstract

The present systematic literature review aims to analyze the literature on factors affecting capital structure decisions of commercial banks of Ethiopia to identify the existing gaps and the level of existing research in the field and to provide direction for future research. The review was conducted using 11 relevant and available scholarly studies that were published in any time period mainly using access open search engines and databases because of shortage of studies on the specified review and lack of access to the known database. Different key words were used to identify the articles. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) framework was employed to analyze the research work on capital structure decisions. The inclusion and exclusion criteria were specified in the review protocol. The descriptive analysis was performed based on different parameters to arrive at conclusions. A citation analysis was also performed to recognize impactful authors and papers. The findings revealed that most of the variables of interests explored in the studies were contradicting each other and the previous literature variables. The capital structure research studies were conducted by considering few variables and most of the studies were not cited. The findings regarding to the theories supported with factors affecting capital structure decision of commercial banks of Ethiopia was contradicting each other and not justified. The banking literature still doesn't cover the capital structure of banks very much. There is currently a lack of clarity regarding how banks determine their capital structure and what variables affect their corporate financing behavior. Therefore, it is recommended that the concerned body conduct an in-depth study of the decisions banks make about their capital structure by identifying pertinent elements.