bluuebunny/crossref_metadata_2025_split huggingface dataset:
Climate Chaos, Human Solutions
Authors: Smith Erica 
Published: January 2025

Abstract
This article discusses four recently published books1 that join an expanding corpus foregrounding mobility as a key dynamic of life in a heating world. Taken together, these titles construct a more explicit, applied dialogue about the process of producing solutions and policies that combat rising global temperatures. I primarily employ Mimi Sheller's mobility justice framework to identify the intersections between movement, inequality, and environmental justice, and go on to explore what each author proposes in terms of measures going forward. A tension arises between clear-cut solutions that advocate specific mobility strategies, like mass migration, for climate adaptation, and holistic mobility approaches that consider the complex sociopolitical and environmental factors at play. In the spirit of interdisciplinarity, I consider which elements of each approach are worth holding onto to continue to challenge static narratives of global climate resilience.
Resection of a ventrally located ossified thoracic spinal meningioma: illustrative case
Authors: Menéndez Ricardo H. , Barea Horacio , Lehrner Pablo E. , Mazza Elizalde Delfina , Elvira Jaqueline , Arias German , Castelletti Natalia , Mayoni Sabrina , Sole Horacio A. 
Published: January 2025

BACKGROUND
Resection of calcified meningiomas in the ventral thoracic spinal canal remains a formidable surgical challenge despite advances in technology and refined microsurgical techniques. These tumors, which account for a small percentage of spinal meningiomas, are characterized by their hardness, complicating safe resection and often resulting in worse outcomes than their noncalcified counterparts.

OBSERVATIONS
The authors present the case of a 68-year-old woman with a ventrally located ossified meningioma at the T9–10 level, successfully treated via a posterolateral transpedicular approach. Additionally, they conducted a systematic review of the literature following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, focusing on the origins, imaging findings, surgical strategies, and outcomes of calcified meningiomas in the ventral thoracic spinal canal. Data were extracted and analyzed from 15 articles encompassing 18 cases.

LESSONS
Calcified meningiomas in the ventral thoracic spinal canal require meticulous preoperative planning and a tailored surgical approach to optimize outcomes. The posterolateral transpedicular approach offers a balance between adequate exposure and minimizing spinal cord manipulation, making it a viable option for resecting these challenging tumors. A single facetectomy and pediculotomy do not compromise long-term spinal stability. Technological adjuncts, including ultrasonic aspiration, neuromonitoring, and endoscopic assistance, can further enhance surgical safety and effectiveness.
https://thejns.org/doi/10.3171/CASE24603
More Atypical than Atypical Alzheimer’s Disease Phenotypes: A Treviso Dementia (TREDEM) Registry Case Report
Authors: Gallucci Maurizio , Mazzarolo Anna Paola , Focella Lucia , Berlin Elisa , Fiore Vittorio , Di Paola Francesco , Bendini Matteo , Zanusso Gianluigi , Fenoglio Chiara , Galimberti Daniela , Bonanni Laura 
Published: January 2025

Background: A 57-year-old right-handed man was admitted to the Treviso Memory Clinic due to the presence of memory forgetfulness, repetition of the same questions, episodes of confusion, initial difficulties in performing complex tasks and easy distraction over the past two years, as well as recurrent and never-happened-before car accidents. Objective: We report a peculiar case of an early onset Alzheimer’s disease (AD) with an unusual symptomatology, apparently not fitting in any of the categorized atypical forms of AD nor being representative of a typical amnestic AD. Methods: The patient underwent a neuropsychological, structural, and metabolic cerebral evaluation by MRI and 18F-FDG PET, together with the search for cerebral amyloid (amyloid PET), a genetic testing for dementia related genes and the dosage of CSF protein biomarkers of neurodegenerative conditions. Results: We observed a convergence of predominant frontal (dysexecutive, verbal disinhibition) and posterior (visuospatial) features of cognitive impairment. Structural MRI sequences showed subarachnoid spaces of the vault enlarged in the fronto-parietal region with anterior and posterior cortical atrophy. The hippocampus appeared preserved. The 18F-FDG PET scans showed hypometabolism in the prefrontal, lateral temporal, posterior parietal, and occipital regions bilaterally. The 18F-Flutemetamol scan showed a diffused uptake of the amyloid tracer at the cerebral cortex. CSF biomarkers were compatible with Alzheimer’s disease (AD). Conclusion: This case report presented with clinical phenotypic aspects atypical of AD, both frontal and posterior, never described as concomitant in the most accredited criteria for atypical AD, and appeared therefore more atypical than each of the atypical AD phenotypes already reported.
Penguatan Etika dan Tanggung Jawab Sosial Mahasiswa Melalui Implementasi Budaya Organisasi yang Berkelanjutan di HIMA PPKn Universitas Pamulang
Authors: Utaminingsih Sri , Shella Rachmawaty  , Haryanti Amelia , Hendri  
Published: January 2025

Ethics and social responsibility are important aspects in shaping individuals who are responsible and care about society. Students are future agents of change who need to be formed within the framework of ethics and social responsibility. The Pancasila and Citizenship Education Study Program Student Association (HIMA PPKn) understands the importance of this aspect and has started efforts to implement it in a sustainable organisational culture. The purpose of this activity is to strengthen students' ethics and social responsibility through the implementation of a sustainable organisational culture in HIMA PPKn. The method of implementing this activity involves developing an organisational culture that promotes ethics, integrity, participation in social activities, and self-development. In addition, students also receive counselling related to ethics and social responsibility. Sustainable social programmes are run as a form of positive contribution to society and the environment. The result of this activity is an increased understanding of ethics and social responsibility among students, especially the management of HIMA PPKn. They grow and develop as socially responsible individuals who are able to provide concrete benefits to society. The social programmes run also have a positive impact on the community. Suggestions for the future evaluation and expansion of programs that have been carried out are important steps in strengthening a sustainable organizational culture in developing student ethics and social responsibility. Furthermore, it is hoped that this activity can be an inspiration for other student organisations to strengthen these values in their organisational culture and make a greater contribution to society and the nation.
Sosialisasi Badan Permusyawaratan Desa Dalam Meningkatkan Demokrasi Lokal
Authors: Fakhruri Hajmi , Marlina Lina , Aulawi Anton 
Published: January 2025

This community service aims to discover how village deliberative bodies improve local democracy and what obstacles village deliberative bodies have in improving local democracy in Kramatlaban village, sub-district. Padarincang district. attack prov. offer. This community service uses a survey method to the direct location. The subjects of this community service are the chairman of the Kramatlaban village BPD, the Kramatlaban village BPD secretary, the Kramatlaban village head, the Kramatlaban village secretary and the Kramatlaban village community. The results of community service show that the BPD in Kramatlaban Village has carried out its main duties and functions, namely establishing Village Regulations together with the Village Head, accommodating and channeling community aspirations, and supervising the Village Head's performance well. There are 2 (two) obstacles to BPD in carrying out its role, namely internal and external factors. The following are internal factors: (1) Facilities, (2) Financial obstacles, (3) Limited time. Meanwhile, for external factors: (1) Participation from the community is less than optimal. The efforts made by the BPD to improve local democracy are: (1) Providing knowledge to the community about the importance of democracy, (2) Providing any information on village community management reports to the village government, and (3) Carrying out outreach with the community regarding the functions and duties of the BPD.
Analisis Smart Governance di Kota Bengkulu
Authors: Mauludi M. Rezza , Nurrahman Agung 
Published: January 2025

Pemerintah Kota Bengkulu telah mengadopsi smart city khususnya dimensi smart governance dalam penyelenggaraan digitalisasi pelayanan publik. Namun, masih terdapat permasalahan diantaranya berkaitan dengan adanya laman website yang tidak dapat diakses. Penelitian ini bertujuan untuk memperoleh gambaran umum dan menjelaskan smart governance di Kota Bengkulu. Metode yang digunakan ialah Quasi Qualitative. Alasan digunakan metode tersebut ialah karena hasil penelitian yang diperoleh menggunakan teori sebagai dasar pemikiran dari awal penelitian atau alat analisis di lapangan. Hasil penelitian menunjukkan bahwa terdapat penerapan smart governance melibatkan berbagai elemen, diantaranya elemen pemerintah, swasta, dan masyarakat. Namun, aspek partisipasi menunjukkan adanya keterlibatan masyarakat yang masih terbatas dan pada aspek strategi politik menunjukkan bahwa belum adanya dukungan regulasi daerah yang secara khusus mengatur penerapan tersebut. Di sisi lain, Pemerintah Kota Bengkulu menunjukkan komitmen positif melalui penyediaan layanan publik berbasis online, adanya pengembangan infrastruktur dan transparansi pemerintahan. Kesimpulannya, penerapan smart governance di Kota Bengkulu terselenggara dengan cukup baik, dan membutuhkan peningkatan. Rekomendasi penelitian menunjukkan bahwa Pemerintah Kota Bengkulu sebaiknya dapat menyusun kebijakan daerah yang dapat mendukung penerapan smart governance, menyusun prioritas kebutuhan infrastruktur, meningkatkan kuantitas dan kualitas sosialisasi layanan publik berbasis online, dan mengembangkan mekanisme kolaborasi tidak hanya dengan pihak swasta, tetapi juga dengan pihak akademisi dan dari unsur media.
Kata kunci: Digitalisasi Pelayanan Publik, Smart City, Smart Governance, Transformasi Digital.
Analisis Sosial dan Teknologi Informasi dalam Pengelolaan Kualitas Udara Perkotaan: Studi Kasus di Kota Jakarta dan Surabaya
Authors: Khofiya Nidaan , Sumayya Siti Azzahra 
Published: January 2025

Kualitas udara perkotaan merupakan isu krusial yang mempengaruhi kesehatan dan kesejahteraan masyarakat di kota-kota besar. Penelitian ini bertujuan untuk menganalisis peran teknologi informasi dan faktor sosial dalam pengelolaan kualitas udara di Jakarta dan Surabaya sebagai dua kota besar di Indonesia. Studi ini menggabungkan metode kuantitatif dan kualitatif untuk mengevaluasi dampak teknologi informasi terhadap pemantauan dan pengelolaan kualitas udara, serta bagaimana persepsi dan perilaku masyarakat mempengaruhi efektivitas kebijakan lingkungan. Data dikumpulkan melalui survei terhadap penduduk, analisis data kualitas udara dari stasiun pemantauan, dan wawancara dengan pejabat pengelola lingkungan. Hasil penelitian menunjukkan bahwa penggunaan teknologi informasi, seperti aplikasi pemantauan udara dan sistem peringatan dini, telah meningkatkan kesadaran masyarakat dan respon terhadap kualitas udara yang buruk. Namun, ada perbedaan signifikan antara Jakarta dan Surabaya dalam hal integrasi teknologi dan partisipasi masyarakat, yang dipengaruhi oleh faktor sosial dan infrastruktur yang berbeda di masing-masing kota. Studi ini menyimpulkan bahwa sementara teknologi informasi dapat memfasilitasi pengelolaan kualitas udara dengan cara yang lebih efisien, keberhasilan implementasinya sangat bergantung pada keterlibatan aktif masyarakat dan dukungan kebijakan yang sesuai. Rekomendasi dari penelitian ini mencakup peningkatan investasi dalam teknologi pemantauan, serta penguatan kampanye kesadaran lingkungan yang disesuaikan dengan kebutuhan lokal di Jakarta dan Surabaya.
Kata kunci: Kualitas Udara, Teknologi Informasi, Sosiologi Masyarakat, Jakarta, Surabaya, Pengelolaan Lingkungan.
Impact of antibiotic prophylaxis on gut microbiota in colorectal surgery: insights from an Eastern European stewardship study
Authors: Văcărean-Trandafir Irina Cezara , Amărandi Roxana-Maria , Ivanov Iuliu Cristian , Dragoș Loredana Mihaiela , Mențel Mihaela , Iacob Ştefan , Muşină Ana-Maria , Bărgăoanu Elena-Roxana , Roată Cristian Ene , Morărașu Ștefan , Țuțuianu Valeri , Ciobanu Marcel , Dimofte Mihail-Gabriel 
Published: January 2025

IntroductionAntibiotic overuse is driving a global rise in antibiotic resistance, highlighting the need for robust antimicrobial stewardship (AMS) initiatives to improve prescription practices. While antimicrobials are essential for treating sepsis and preventing surgical site infections (SSIs), they can inadvertently disrupt the gut microbiota, leading to postoperative complications. Treatment methods vary widely across nations due to differences in drug choice, dosage, and therapy duration, affecting antibiotic resistance rates, which can reach up to 51% in some countries. In Romania and the Republic of Moldova, healthcare practices for surgical antibiotic prophylaxis differ significantly despite similarities in genetics, culture, and diet. Romania's stricter healthcare regulations result in more standardized antibiotic protocols, whereas Moldova's limited healthcare funding leads to less consistent practices and greater variability in treatment outcomes.MethodsThis study presents the results of a prospective cross-border investigation involving 86 colorectal cancer patients from major oncological hospitals in Romania and Moldova. We analyzed fecal samples collected from patients before and 7 days post-antibiotic treatment, focusing on the V3–V4 region of the 16S rRNA gene.ResultsOur findings indicate that inconsistent antibiotic prophylaxis policies—varying in type, dosage, or therapy duration—significantly impacted the gut microbiota and led to more frequent dysbiosis compared to stricter prophylactic antibiotic practices (single dose, single product, limited time).DiscussionWe emphasize the need for standardized antibiotic prophylaxis protocols to minimize dysbiosis and its associated risks, promoting more effective antimicrobial use, particularly in low- and middle-income countries (LMICs).
Evaluating atherogenic index of plasma as a predictor for metabolic syndrome: a cross-sectional analysis from Northern Taiwan
Authors: Chen Liang-Sien , Chen Yu-Rui , Lin Yi-Hsiu , Wu Hung-Keng , Lee Yan Wen , Chen Jau-Yuan 
Published: January 2025

BackgroundThe rising global prevalence of metabolic syndrome (MetS), characterized by a constellation of cardiovascular risk factors, underscores the urgent need to identify reliable predictive biomarkers. We hypothesize that an elevated atherogenic index of plasma (AIP) predicts MetS risk through lipid imbalance, but population-specific variations in its predictive strength remain unexplored. Our study aimed to assess AIP), a ratio of triglycerides to high-density lipoprotein cholesterol, as a predictor of MetS.MethodBetween 2014 and 2018, our cross-sectional study collected and analyzed health examination data from 9,202 Northern Taiwan Medical Center employees without cardiovascular diseases, diabetes, and end-stage renal disease (ESRD). Our study classified AIP levels equally into three tertiles and evaluated their impact on MetS through a logistic regression model.ResultsAfter adjusting for age, gender, BMI, SBP, FPG, and LDL in our models, the ORs for MetS in the second and third tertiles of the AIP were 3.81 (95% CI: 2.33 to 6.21; OR: 37.14, 95%: 23.22 to 59.39). In addition, women have a higher MetS risk associated with elevated AIP than men across all models.ConclusionOur research identified the AIP as a significant predictive marker for the prevalence of MetS, suggesting its potential utility in clinical risk assessment and indicating the need for further research to explore its application in preventive strategies and therapeutic interventions.
The efficacy of resveratrol supplementation on inflammation and oxidative stress in type-2 diabetes mellitus patients: randomized double-blind placebo meta-analysis
Authors: Zhu Peiye , Jin Yunrui , Sun Jiya , Zhou Xia 
Published: January 2025

BackgroundThe effects of resveratrol supplementation on inflammation and oxidative stress in patients with type 2 diabetes mellitus (T2DM) were controversial. A meta-analysis was performed to assess the changes in levels of inflammation and oxidative stress in patients with T2DM.MethodsRelevant literatures before November 6, 2024 were screened through Web of Science,Embase,the Cochrane Library and other sources (ClinicalTrials, ProQuest Dissertations and Theses). The quality of the literature was evaluated according to the Cochrane Handbook of Systematic Reviews. The study quality was assessed using the risk-of-bias 2 tool and the Grading of Recommendations Assessment,Development and Evaluation (GRADE) system. Review Manager 5.3 conducted meta-analysis of the data included in the literature.ResultsThis meta-analysis was conducted in six randomized controlled trials involving 533 participants. Our results showed that supplementation with resveratrol significantly reduced C-reactive protein levels(SMD = -1.40, 95%CI(-2.60, -0.21), P = 0.02; Level of evidence: low), lipid peroxide levels (SMD = -0.99, 95%CI(-1.36, -0.61), P &lt; 0.00001; Level of evidence: low), 8-isoprostanes(SMD = -0.79, 95%CI(-1.16, -0.42), P &lt; 0.0001; Level of evidence: low) and oxidative stress score (SMD = -1.62, 95%CI(-2.49, -0.75), P = 0.0003; Level of evidence: very low). In addition, compared to placebo, Supplementation with resveratrol significantly increased glutathione peroxidase levels (SMD = 0.38, 95%CI(0.03, 0.74), P = 0.04; Level of evidence:low) and catalase levels (SMD = 0.33, 95%CI(0.03, 0.63), P = 0.03; Level of evidence: low). However, no significant difference was observed in improving interleukin-6 levels (SMD = -1.35, 95%CI(-2.75, -0.05), P = 0.06; Level of evidence: very low), tumor necrosis factor α levels (SMD = -3.30, 95%CI(-7.47, 0.87), P = 0.12; Level of evidence: very low), superoxide dismutase levels (SMD = 0.39, 95%CI(-0.26, 1.04), P = 0.24; Level of evidence: very low), total antioxidant capacity levels (SMD = 0.39, 95%CI(-0.23, 1.00), P = 0.21; Level of evidence: very low) and malondialdehyde levels (SMD = -3.36, 95%CI(-10.30, 3.09), P = 0.29; Level of evidence: very low).ConclusionResveratrol improved inflammation and oxidative stress in T2DM patients to some extent. This provides a new idea and method for clinical treatment. However, due to the limitations of the study, more large-sample, multi-center clinical studies are needed to verify this conclusion.
Microbiological quality of the air in the area of influence of the former wastewater treatment plant in Cajamarca, Peru
Authors: Rodriguez-Zevallos Claudia E. , Sanchez-Altamirano Jessica K. , Sanchez-Peña Marco A. , Diaz Kenny 
Published: January 2025

It has been determined that there is air pollution within wastewater treatment plants and their surrounding areas. This impacts the health of nearby populations. Therefore, this research aimed to evaluate the air’s microbiological quality in the area of influence of the former Wastewater Treatment Plant (WWTP) in the city of Cajamarca. Microbiological air sampling was conducted during the rainy and dry seasons using the RCS Standard Hycon air sampler, planting on tryptic soy agar medium to determine the total count of all microorganisms, bacteria, and fungi separately. OSHA (Occupational Safety and Health Administration), PN-89/Z-04111/02, and PN-89/Z-04111/03 were the standards used to determine the air quality of the study area since Peru currently does not have such regulation standards. The highest values obtained were 4560 CFU/m³ and 4360 CFU/m³ during the dry season. Sixteen concentrations of the total microorganism count exceeded the limits established by OSHA standards, and ten concentrations of bacteria exceeded the Polish standard PN-89/Z-04111/02. Although the concentrations of fungi were high, they did not exceed any reference limits. We determined a positive correlation between the concentration of microorganisms and the relative humidity, with a maximum of 85.67% humidity during the dry season. Additionally, a negative correlation with wind speed was found, with values ranging from 0.37 m/s to 2.58 m/s during the dry season and from 0.37 m/s to 1.87 m/s during the rainy season. Genera of public health importance such as Staphylococcus and Penicillium were identified. Finally, a survey was conducted among the nearby population to assess the impact on public health. And, it was established that the health impact on the surrounding populations is mainly low.
The immune landscape of fetal chorionic villous tissue in term placenta
Authors: Doratt Brianna M. , True Heather E. , Sureshchandra Suhas , Qiao Qi , Rincon Monica , Marshall Nicole E. , Messaoudi Ilhem 
Published: January 2025

IntroductionThe immune compartment within fetal chorionic villi is comprised of fetal Hofbauer cells (HBC) and invading placenta-associated maternal monocytes and macrophages (PAMM). Recent studies have characterized the transcriptional profile of the first trimester (T1) placenta; however, the phenotypic and functional diversity of chorionic villous immune cells at term (T3) remain poorly understood.MethodsTo address this knowledge gap, immune cells from human chorionic villous tissues obtained from full-term, uncomplicated pregnancies were deeply phenotyped using a combination of flow cytometry, single-cell RNA sequencing (scRNA-seq, CITE-seq) and chromatin accessibility profiling (snATAC-seq).ResultsOur results indicate that, relative to the first trimester, the frequency of fetal macrophages (HBC, proliferating HBC) is significantly reduced, whereas that of infiltrating maternal monocytes/macrophages (PAMM1b, PAMM1a, PAMM2, MAC_1) increased in T3. PAMM1b and HBCs exhibit the most phagocytic capacity at term highlighting their regulatory role in tissue homeostasis in late pregnancy. The transcriptional profiles of resident villous immune subsets exhibit a heightened activation state relative to the relative to T1, likely to support labor and parturition. Additionally, we provide one of the first insights into the chromatin accessibility profile of villous myeloid cells at term. We next stratified our findings by pre-pregnancy BMI since maternal pregravid obesity is associated with several adverse pregnancy outcomes. Pregravid obesity increased inflammatory gene expression, particularly among HBC and PAMM1a subsets, but dampened the expression of antimicrobial genes, supporting a tolerant-like phenotype of chorionic villous myeloid cells. We report a decline in HBC abundance accompanied by an increase in infiltrating maternal macrophages, which aligns with reports of heightened chorionic villous inflammatory pathologies with pregravid obesity. Finally, given the shared fetal yolk-sac origin of HBCs and microglia, we leveraged an in vitro model of umbilical cord blood-derived microglia to investigate the impact of pregravid obesity on fetal neurodevelopment. Our findings reveal increased expression of activation markers albeit dampened phagocytic capacity in microglia with pregravid obesity.DiscussionOverall, our study highlights immune adaptations in the fetal chorionic villous with gestational age and pregravid obesity, as well as insight towards microglia dysfunction possibly underlying poor neurodevelopmental outcomes in offspring of women with pregravid obesity.