bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mathematical model of the impact of 12.7 mm kinetic action ammunition on an armored obstacle with additional armor
Authors: Dachkovskyi Volodymyr , Datsenko Ivan , Golub Viktor , Sedov Sviatoslav , Kondratiuk Ihor , Pavlov Denys , Mazurenko Valerii , Kovalov Oleksandr 
Published: February 2023

Abstract. In today's conditions, there is a need to find new and effective ways (means) to protect armored vehicles and increase their protection against modern means of destruction, as evidenced by the analysis of the damage received by armored vehicles during the repulsion of armed aggression against Ukraine.
Various methods and means of additional protection always require practical verification of their feasibility.
The purpose of this article is to present the main approaches to assessing the level of stability of an armored obstacle with additional armor and to build a mathematical model of the impact of 12.7 mm kinetic munitions on an armored obstacle with additional armor based on experimental data.
To assess the relative properties of the armor barrier to the destructive energy of the munitions, the experimental-statistical method of mathematical modeling of the process of influence of the energy of the munitions on the armor barrier of armored vehicles was used, in which the experiment is considered as the main source of information about the process, and the methods of probability theory and mathematical statistics are the main means of processing the results of the experiment.
The experimental study allowed to check the resistance of the armored barrier with additional armor to ammunition of 12.7 mm caliber, which destroys it under the action of kinetic energy.
As a result of a multifactorial experiment, experimental data were obtained. Using the experimental data, a mathematical model of the impact of 12.7 mm kinetic ammunition on an armored obstacle with additional armor was built, which takes into account the angle of the meeting of the munition with the armored obstacle, the distance from the armored obstacle to the additional armor, the thickness of the additional armor. This mathematical model can be used to find the optimal additional armor of armored vehicles, taking into account the angle of inclination, the distance of additional armor to the main armor and the thickness of additional armor.
Assessment of robustness of hinged-bar systems
Authors: Perelmuter Anatolii 
Published: February 2023

Typically in structural design, foreseeable loads are assumed in a dimensioning exercise. Structures can, however, be exposed to largely unforeseeable events such as intense environmental phenomena, accidents, malicious acts, and planning or execution errors. This circumstance determines the interest in the problem of structural robustness, which has been the subject of many recent works.
This paper focuses on methods for assessing the robustness of hinged bar systems, considering truss structures as an example. They are the simplest in terms of computation, but make it possible to fully illustrate the proposed approach.
First, the differences between progressive collapse (description of the process) and the disproportionate propagation of local failures (description of the state) are analyzed. The generalizing nature of the concept of robustness and its differences from the concept of invulnerability are pointed out.
The paper considers the problem of measuring robustness. The known quantitative estimates of robustness are analyzed focusing on estimates that are invariant with respect to the stress state, as more general ones. The paper considers estimates that use such properties of the stiffness matrix as the condition number, or based on a comparison of the determinants of the original and changed stiffness matrices. It is pointed out that the degree of static indeterminacy can serve only as a necessary, but insufficient measure of robustness.
The paper considers a well-known method of robustness assessment using a redundancy matrix determined by the forces that must be applied to assemble the system from elements with the length different from the design one. This method is opposed to the use of a projection matrix, the main diagonal elements of which indicate the degree of participation of the bars in ensuring robustness. The main properties of the idempotent projection matrix are considered. The paper illustrates the possibility of recalculating the projection matrix for the changed system with the help of the Jordan elimination step. A simple example demonstrates assembling and changing the projection matrix.
In addition to the failure of the bar, the case of its damage (partial failure) is also considered, it is shown how it affects the change in the projector and the redistribution of internal forces.
Modified direct method in static problems of axi-symmetric non-thin plates
Authors: Koshevyi Oleksandr , Levkivskyi Dmytro , Chubarev Anton , Yansons Maryna 
Published: February 2023

The initial equations for solving the axisymmetric problem are given and consideredboundary conditions on the end surfaces and average section of the design element. As a result, we get a system of partial differential equations that can be solved by the numerical-analytical (modified) method of straight lines. The transformation of the reduced equations of equilibrium in parts, as well as the reduced models of the boundary conditions of the end surfaces and the average section, are shown. As a result, a boundary value problem for the system of reduced differential equations in ordinary derivatives written in the Cauchy form with boundary conditions of the general form is obtained.
The thermal conductivity of the cylindrical wall was calculated, the results were compared with analytical calculations and results of other authors, which confirms the reliability of the developed methodology.
A computer simulation of the stress-strain state of a cylindrical structural element due to the complex action of temperature, force and kinematic effects was carried out.
Important conclusions have been made for the use of the modified method of straight lines, which is free from the complications that arise when using the classical method of straight lines.
Numerical implementation of multicriteria parametric optimization of minimum surface shell on a square contour under thermforce loading
Authors: Ivanchenko Hryhorii , Koshevyi Oleksandr , Koshevyi Oleksandr 
Published: February 2023

The article considers the numerical study of the multicriteria parametric optimization of the minimum surface shell on the square contour under thermoforce loading. The mathematical algorithm for solving the problem of multicriteria parametric optimization of minimal surfaces shellsis described: the necessary output data are given, which target functions can be used, design variables and constraints are described. The influence of initial data on the numerical study of multicriteria parametric optimization was shown. The calculation of necessary components and matrices for multicriteria parametric optimization of minimal surfaces shells, as well as methods of its simplification, depending on the initial data was made. Was shown in which cases the algorithm is executed successfully, and where it was necessary to return to change the initial parameters.
The sensitivity analysis of multi-criteria parametric optimization of minimal surfaces shells is presented. In article reveals the inner essence of the structure's work while the optimization calculation was done. Work with internal forces and stresses, the connection with the finite element method and its stiffness matrix were made.
The process and methodology of setting ofthermoforce loadare revealed.All initial parameters, as well as how the load works with multicriteria parametric optimization are shown.
The numerical experiment made it possible to reduce the weight of minimum surface shell on the square contour by 5%, and the movement along the coordinate axes by 38%, which are the target functions of multicriteria parametric optimization. Redistribution of the thickness of the minimum surface shell on the square contour from 1 mm to 31 mm was realized. The interaction of the objective functions is shown - they conflict, as well as the graphs of changes in Mises stresses, shear stresses and strain energy, which makes it possible to reveal the internal processes of multi-criteria parametric optimization of the minimum surface shell on a square contour.
Subject of this study is an interesting applied problem for construction mechanics, as it is the first time to display the application of two types of optimization on one research object.
Compilation of calculated combinations in according with EN 1990
Authors: Perelmuter Anatolii 
Published: February 2023

The article addresses one of the main issues that arise in the planned development of a new version of domestic standards, which is aimed at closer convergence with the European normative document EN 1990 in terms of calculation methods. If these methods are not fully accepted, then at least the principled positions are agreed, if possible preserving the domestic tradition
An overview of the approaches of European standards EN 1990 to the compilation of design combinations of effects on building structures is given. The information on the method of choosing the calculated combination of influences of different groups of limit states taking into account different types of representative values of variable influences is generalized. Discrepancies with the methods of normative documents in force on the territory of Ukraine (DBN) on the calculation of building structures are indicated. Attention is drawn to the variability of Eurocode rules for the construction of settlement connections in relation to the situations under consideration, such variability is absent in the DBN.
A compromise approach is proposed, which combines the principles of EN 1990 with the accumulated domestic experience and allows to significantly reduce the growth of design loads. The examples show that the increase in design effort causes significantly less increase in the cost of building materials.
QMH (Quantifying Mental Health) Key Technologies
Authors: Ternyik Stephen I. , Fermelia Al 
Published: February 2023

In order to understand the chaotic nature of mental health, a forensic simulation of the mental health system is under development. This paper discusses the requirements and key technologies based on Ontological Engineering. Ontological engineering is expected to provide a foundation of so-called Content-Directed Artificial Intelligence which relies on the development of an _integrated World Knowledge DataBase _(_WKDB)_ necessary for the understanding of mental health.

Mental health techniques are required in order to develop a mitigation plan for the alleviation fo pain which is of both mental as well as physical. This paper address the requirements for the mitigation of mental pain. Specifically Anxiety and depression are the most common problems, with around 1 in 10 people affected at any one time. How do mental health problems problems affect people? Anxiety and depression can be severe and long-lasting and have a big impact on people's ability to get on with life. Predictions of beliefs and thoughts (good and bad) are brain outputs due to the measured vision, hearing inputs, and autonomic activation of one's residual WKDB.
PENERAPAN BAURAN PROMOSI DI QUEST HOTEL SURABAYA PADA MASA PANDEMI COVID-19
Authors: Yudhiasta Sheidy 
Published: February 2023

Penelitian ini bertujuan untuk mengidentifikasi penerapan bauran promosi pada Quest Hotel Surabaya saat pandemi Covid-19. Penelitian ini menggunakan jenis penelitian kualitatif deskriptif dengan metode wawancara mendalam. Informan adalah pegawai dan pemangku kebijakan di departemen Sales & Marketing. Pengambilan sumber data menggunakan teknik purposive sampling. Temuan penelitian menunjukkan bahwa Quest Hotel Surabaya menerapkan bauran pemasaran menggunakan (i)advertising dengan media radio, banner, dan online advertising menggunakan website dan sosial media, (ii)personal selling dengan membina hubungan baik dengan konsumen menggunakan telepon, WhatsApp, serta kunjungan secara langsung ke lembaga-lembaga dan instansi pemerintah maupun swasta, (iii)sales promotion dengan memberikan potongan harga kamar di beragam booking platform seperti website dan online travel agent serta mengikuti exhibition, (iv)direct marketing dengan mengirimkan e-brochure melalui email blast dan telemarketing, (v)public relation dengan aktif mengunjungi media-media dan ikut berpartisipasi dalam event-event lokal.

Kata kunci: Bauran Promosi, Hotel, Pandemi Covid-19.
PARIWISATA KEBANGSAAN: TOLERANSI DAN PLURALISME DI DESA WONOREJO, KABUPATEN SITUBONDO
Authors: HIDAYAT RUSDI , RASDIYAH RESA , PRABOWO BUDI , NURYANANDA PRAJA FIRDAUS , ALAWI A. MUAMMAR 
Published: February 2023

Terletak sangat dekat dengan Taman Nasional Baluran dan pantai timur Jawa Timur, desa Wonorejo merupakan daerah yang sangat potensial untuk pariwisata. Desa ini diberi label sebagai “desa kebangsaan”. Label tidak muncul begitu saja. Wonorejo memiliki masyarakat yang sangat pluralistik. Di sana tinggal tiga agama, yaitu Islam, Kristen, dan Hindu. Karena seolah-olah mencerminkan “Bhinneka Tunggal Ika” Indonesia, mereka hidup di sana dengan rukun dan tingkat toleransi yang sangat tinggi. Wonorejo dengan demikian menjadi tujuan wisata reguler, terutama bagi orang-orang yang mencintai alam. Tapi, desa ini bukannya tanpa masalah. Salah satu kendala yang kami temukan adalah dalam pengelolaan pariwisata mereka. Menggunakan observasi partisipatif dan wawancara mendalam, penelitian kami menemukan celah di desa yang indah ini. Masalah mereka terdiri dari kurangnya manajemen kolektif, pembangunan yang tidak merata, dan krisis kepemimpinan. Dengan menggunakan pendekatan ABCD (pengembangan masyarakat berbasis aset), penelitian ini bertujuan untuk mengidentifikasi dan memberikan alternatif solusi atas permasalahan yang mereka hadapi. Menjadi destinasi wisata yang sepenuhnya menghibur alam dengan pluralisme dan toleransi dalam masyarakat akan menjadi tujuan yang sangat mulia untuk dicapai penelitian ini.

Kata kunci: kebangsaan, pariwisata, pluralisme, toleransi, desa
PEMASARAN EKOWISATA WAY LALAAN MELALUI KONSEP STORYNOMIC TOURISM SEBAGAI STRATEGI PELESTARIAN BUDAYA DAN SEJARAH
Authors: ASTRIYANTIKA MEYLIANA 
Published: February 2023

Konsep ekowisata saat sebagai implementasi jenis kegiatan wisata dengan menjaga kelestarian sumber daya, ditambahkan dengan berbagai teknik interpretasi objek sehingga pengunjung mendapat pengetahuan, pemahaman, dan kesadaran akan pentingnya kelestarian daya tarik. Keunggulan sector pariwisata, budaya, dan pertanian menjadi potensi untuk dikelola secara kolaborasi dengan konsep ekowisata di salah satu destinasi prioritas Kabupaten Tanggamus yang sudah cukup dikenal masyarakat umum yaitu Air Terjun Way Lalaan. Penelitian dilakukan pada bulan Juni-September di Kabupaten Tanggamus dengan metode observasi lapang, wawancara mendalam dan studi literatur. Selanjutnya analisis data yang digunakan dalam penelitian ini adalah analisis deskriptif kualitatif. Dari data yang ada, jumlah kunjungan dalam kurun waktu 4 tahun (2016-2019) mengalami peningkatan namun masih jauh di bawah target, terlebih dengan adanya wabah covid-19 yang mempengaruhi minat wisatawan untuk berkunjung, sehingga dibutuhkan strategi untuk meningkatkan permintaan kunjungan ke Way Lalaan. Kawasan ini telah dikenal sejak zaman kerajaan, menciptakan kepercayaan, sejarah dan budaya turun-temurun yang dijaga oleh masyarakat sekitar, lalu menjadi daya tarik sendiri bagi destinasi ini. Potensi unggulan berupa 2 buah air terjun yang tidak pernah berhenti mengalir karena sekaligus sebagai sumber irigasi masyarakat dari mata air di pegunungan Tanggamus. Keseluruhan potensi ini mampu menjadi materi untuk disampaikan kepada wisatawan melalui Storynomic Tourism untuk meningkatkan minat wisatawan dengan keunikan konten destinasi melalui cerita adat, tradisi, kuliner, dan budaya. Pemasaran yang dilakukan secara luas dengan memanfaatkan media cetak, media elektronik, kegiatan pameran, jasa influencer, serta kegiatan pembuatan film documenter untuk memperkenalkan kepada masyarakat luas secara online.

Kata kunci: Ekowisata, Strorynomic Tourism, Way Lalaan.
ANTİK YUNAN’DAN YAŞAYAN SÖZLER’DE KADIN
Authors: ÜRETEN Hüseyin 
Published: February 2023

Bu çalışma, tamamı modern dillere çevrilmiş olan Hesiodos, Aristophanes, Aiskhylos, Sophokles, Euripides, Demokritos ve Phaedrus’un eserlerinin satır aralarında gözümüze çarpan ilginç ve anlamlı sözleri bağlamında antik Hellen kadınını konu almaktadır. Çalışmanın belkemiğini antik Hellen dünyasının ünlü şair, yazar, filozof ve ozanlarının eserlerindeki satır aralarında antik Hellen kadınını anlatan sözlerin derlendiği “Antik Yunan’dan Yaşayan Sözler” adlı kitap oluşturmaktadır.
Amacım, hem tematik hem de kronolojik sıraya uyarak, yukarıda adları anılan antikçağın ünlü Hellen şair, yazar, filozof ve ozanların kadın konusundaki düşüncelerini kendi sözleriyle okuyucuya bir kere daha sunmak ve böylece antik Hellen dünyasında kadın konusunda küçük bir gezinti yaptırmaktır.
Elimination of enzymes catalysis compartmentalization enhancing taxadiene production in Saccharomyces cerevisiae
Authors: Zhang Chenglong , Chen Wang , Dong Tianyu , Wang Ying , Yao Mingdong , Xiao Wenhai , Li Bingzhi 
Published: February 2023

Taxadiene is an important precursor in taxol biosynthesis pathway, but its biosynthesis in eukaryotic cell factories is limited, which seriously hinders the biosynthesis of taxol. In this study, it is found that there was the catalysis compartmentalization between two key exogenous enzymes of geranylgeranyl pyrophosphate synthase and taxadiene synthase (TS) for taxadiene synthesis progress, due to their different subcellular localization. Firstly, the enzyme-catalysis compartmentalization was overcome by means of the intracellular relocation strategies of taxadiene synthase, including N-terminal truncation of taxadiene synthase and enzyme fusion of GGPPS-TS. With the help of two strategies for enzyme relocation, the taxadiene yield was increased by 21% and 54% respectively, among them the GGPPS-TS fusion enzyme is more effective. Further, the expression of GGPPS-TS fusion enzyme was improved via the multi-copy plasmid, resulting that the taxadiene titer was increased by 38% to 21.8 mg/L at shake-flask level. Finally, the maximum taxadiene titer of 184.2 mg/L was achieved by optimization of the fed-batch fermentation conditions in 3 L bioreactor, which is the highest reported titer of taxadiene biosynthesis accomplished in eukaryotic microbes. This study provides a successful example for improving biosynthesis of complex natural products by solving the critical problem of multistep enzymes catalysis compartmentalization.
The transcriptomic and epigenetic alterations in type 2 diabetes mellitus patients of Chinese Tibetan and Han populations
Authors: Wang Xian , Liu Jie , Wang Qiuhong , Chen Qiu 
Published: February 2023

BackgroundDue to the distinctive living environment, lifestyle, and diet, the Tibetan community in China has the lowest prevalence of T2DM and prediabetes among numerous ethnic groups, while Han community shows the highest statistic. In this study, we aim to conclude the clinical manifestations of both Tibetan and Han T2DM patients and their association with transcriptomic and epigenetic alterations.MethodsA cross-sectional study including 120 T2DM patients from Han and Tibetan ethnic groups were conducted between 2019 to 2021 at the Hospital of Chengdu University of Traditional Chinese Medicine. The various clinical features and laboratory tests were recorded and analyzed between the two groups. The genome-wide methylation pattern and RNA expression were determined by Reduced Representation Bisulfite Sequencing (RBBS) and Poly (A) RNA sequencing (RNA-seq) from leucocytes of peripheral blood samples in 6 Han and 6 Tibetan patients. GO analysis and KEGG analysis were conducted in differentially expressed genes and those with differentially methylated regions.ResultsCompared to Han, Tibetan T2DM individuals intake more coarse grains, meat and yak butter, but less refined grains, vegetables and fruit. They also showed increased BMI, Hb, HbA1c, LDL, ALT, GGT and eGFR, and decreased level of BUN. Among the 12 patients in the exploratory cohort, we identified 5178 hypomethylated and 4787 hypermethylated regions involving 1613 genes in the Tibetan group. RNA-seq showed a total of 947 differentially expressed genes (DEGs) between the two groups, with 523 up-regulated and 424 down-regulated in Tibetan patients. By integrating DNA methylation and RNA expression data, we identified 112 DEGs with differentially methylated regions (overlapping genes) and 14 DEGs with promoter-related DMRs. The functional enrichment analysis demonstrated that the overlapping genes were primarily involved in metabolic pathways, PI3K-Akt signaling pathway, MAPK signaling pathway, pathways in cancer and Rap1 signaling pathway.ConclusionOur study demonstrates the clinical characteristics of T2DM differ subtly between various ethnic groups that may be related to epigenetic modifications, thus providing evidence and ideas for additional research on the genetic pattern of T2DM.
Evaluating SARS-CoV-2 antibody reactivity to natural exposure and inactivated vaccination with peptide microarrays
Authors: Zheng Peiyan , Ma Jing , Yang Jiao , Liao Baolin , Cheng Zhangkai J. , Xue Mingshan , Li Shiyun , Fang Yanting , Lin Runpei , Zhang Guizhen , Huang Huimin , Hu Fengyu , Ma Hongwei , Sun Baoqing 
Published: February 2023

ObjectiveVaccination is effective tool for preventing and controlling SARS-CoV-2 infections, and inactivated vaccines are the most widely used type of vaccine. In order to identify antibody-binding peptide epitopes that can distinguish between individuals who have been vaccinated and those who have been infected, this study aimed to compare the immune responses of vaccinated and infected individuals.MethodsSARS-CoV-2 peptide microarrays were used to assess the differences between 44 volunteers inoculated with the inactivated virus vaccine BBIBP-CorV and 61 patients who were infected with SARS-CoV-2. Clustered heatmaps were used to identify differences between the two groups in antibody responses to peptides such as M1, N24, S15, S64, S82, S104, and S115. Receiver operating characteristic curve analysis was used to determine whether a combined diagnosis with S15, S64, and S104 could effectively distinguish infected patients from vaccinated individuals.ResultsOur findings showed that the specific antibody responses against S15, S64, and S104 peptides were stronger in vaccinators than in infected persons, while responses to M1, N24, S82, and S115 were weaker in asymptomatic patients than in symptomatic patients. Additionally, two peptides (N24 and S115) were found to correlate with the levels of neutralizing antibodies.ConclusionOur results suggest that antibody profiles specific to SARS-CoV-2 can be used to distinguish between vaccinated individuals and those who are infected. The combined diagnosis with S15, S64, and S104 was found to be more effective in distinguishing infected patients from those who have been vaccinated than the diagnosis using individual peptides. Moreover, the specific antibody responses against the N24 and S115 peptides were found to be consistent with the changing trend of neutralizing antibodies.