bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hubungan Kecerdasan Emosional dan Konsep Diri dengan Hasil Belajar pada Mata Pelajaran Biologi
Authors: Hasiah Afifah Ismi 
Published: June 2023

Tujuan Penelitian: Untuk mengetahui hubungan antara kecerdasan emosional dan konsep diri dengan hasil belajar pada mata pelajaran biologi siswa kelas X SMAN 1 Merlung.
Metodologi: Penelitian ini adalah penelitian deskriptif kuantitatif jenis korelasi. Populasi pada penelitian ini adalah siswa kelas X SMA N 1 Merlung yang terdiri empat kelas dengan jumlah keseluruhan 104 siswa. Instrumen yang digunakan dalam penelitian ini yaitu angket dan dokumentasi hasil belajar. Data dianalisis secara deskriptif kuantitatif
Temuan Utama: Terdapat hubungan yang positif dan signifikan antara kecerdasan emosoinal dan konsep diri dengan hasil belajar pada mata pelajaran biologi siswa kelas X SMA Negeri 1 Merlung. Diperoleh nilai koefisien korelasi ganda sebesar 0,615 dan Fhitung sebesar 30,272 dengan p-value < 0,05. Kontribusi sebesar 37,8% selebihnya dipengaruhi oleh faktor lain.
Keterbaruan/Keaslian dari Penelitian: Mengetahui hubungan kecerdasan emosional dan konsep diri dengan hasil belajar pada mata pelajaran biologi.
Pengembangan Modul Pembelajaran Berbasis Pendekatan Open Ended pada Materi Sistem Persamaan dan Pertidaksamaan Linear
Authors: Hanisan Hanisan 
Published: June 2023

Tujuan Penelitian: Penelitian ini bertujuan untuk: (1) mendeskripsikan karakteristik hasil pengembangan modul pembelajaran berbasis pendekatan open ended; (2) mengetahui kualitas modul pembelajaran berbasis pendekatan open ended pada materi sistem persamaan dan pertidaksamaan linear.
Metodologi: Jenis penelitian ini adalah R & D dengan model 4D yang telah dikurangkan menjadi tiga tahap yakni define, design dan develop. Penelitian ini mengembangkan modul, pemberian tes untuk mengetahui hasil belajar siswa dan pemberian angket untuk melihat respon siswa. Instrumen yang digunakan dalam penelitian ini meliputi: lembar validasi ahli materi dan desain modul, angket tanggapan guru dan siswa, lembar observasi aktivitas siswa, tes hasil belajar dan angket respon siswa.
Temuan Utama: Proses pengembangan modul yang telah dilakukan dilanjutkan tahap validasi dilakukan oleh satu orang ahli materi dan desain dengan rata-rata skor validasi desain 72,3% pada kategori “baik/cukup valid” dan ahli materi dengan rata-rata skor 73,01% pada kategori “baik/cukup valid”. Tahap uji coba perorangan yang melibatkan dua guru matematika, uji coba kelompok kecil yang melibatkan sepuluh orang non subjek dan uji lapangan yang melibatkan satu kelas X MIA 1. Dari hasil analisis yang dilakukan terhadap tes akhir materi sistem persamaan dan pertidaksamaan linear diperoleh 88% nilai siswa mencapai kriteria ketuntasan minimum, hasil observasi aktivitas siswa dalam proses pembelajaran mencapai 84,9% menunjukkan kategori “baik” dan hasil respon siswa diperoleh rata-rata 86,99% dengan kategori sangat baik.
Keterbaruan/Keaslian dari Penelitian: Modul yang dibuat ini mempunyai karakteristik dibandingkan dengan modul-modul yang lain serta berkualitas untuk digunakan oleh guru matematika SMA khusunya pada pembelajaran sistem persamaan dan pertidaksamaan linear.
STRATEGI PEMERINTAH NAGARI MANDEH DALAM MEWUJUDKAN MANGROVE SEBAGAI DESTINASI WISATA
Authors: Abbas Ibnu , Kabullah M. Ichsan 
Published: June 2023

ABSTRAK
Penelitian ini dilatar belakangi dengan adanya upaya yang dilakukan oleh Pemerintah Nagari Mandeh dalam menjadikan lahan mangrove yang berada di nagari tersebut agar dapat dibangun suatu tempat wisata yang berbasis alam. Dimana dalam upaya tersebut hal ini juga sangat berdampak terhadap perekonomian masyrakat di Nagari Mandeh itu sendiri. Penelitian ini bertujuan untuk mendeskripsikan dan menganalisis Strategi Pemerintah Nagari Mandeh dalam mewujudkan mangrove sebagai destinasi wisata.

Penelitian ini menggunakan teori Strategi yang dikemukakan oleh Kotten yang mencakup 4 variabel yaitu strategi organisasi, Strategi program, Strategi dukungan sumber daya dan juga Strategi kelembagaan. Penelitian ini berlokasi di Nagari Mandeh Tarusan dengan unit analisis Pemerintah nagari mandeh. Metode yang diterapkan yaitu metode kualitatif dengan tipe deskriptif, Teknik pengumpulan data menggunakan wawancara dan dokumentasi dan obseevasi. Dalam pemilihan informan, menggunakan teknik purposive sampling. Teknik keabsahan data dilaksanakan dengan metode triangulasi sumber.

Dari hasil Penelitian ini menunjukan bahwa strategi yang digunakan oleh pemerintah nagari sudah maksimal. Dimana dalam strategy corporate nya rencana pembangunan wisata mangrove tersebut telah sesui dengan visi dan misi pemerintah nagari mandeh. Dalam strategy Program, program yang dilakukan oleh pemerintah nagari untuk mewujudkan wisata mangrove tersebut telah dilakukan dengan sebaik mungkin, namun masih adanya kendala terkait perizinan lingkungan yang bertentangan dengan perda yang pada saat sekarang ini telah direvisi, ditahun 2023 akan keluar perda baru yang memperbolehkan pembangunan wisata mangrove tersebut. Dalam Resource Support Strategy pemerintah nagari mengalami kendala anggaran pembangunan wisata mangrove, dimana anggran tersebut di alihkan dalam menanggulangi Covid 19, maka dari itu DKP provinsi memberikan fasilitas pembangunan secara fisik terkait pembangunan wisata mangrove. Begitu juga dengan Institutional Strategy dimana struktur yang mengelola wisata mangrove tersebut pemerintah nagari menunjuk Bumnag yang mengelolanya, akan tetapi SOP dalam pelaksanaannya belum ada sampai saat ini.
Le système pénal intelligent : observations et exigences normatives
Authors: Simmler Monika , Canova Giulia , Schedler Kuno 
Published: June 2023

1 Les technologies de pointe transforment le secteur public en général, mais révolutionnent également de plus en plus le système de justice pénale. Des applications intelligentes sont conçues pour anticiper les infractions, automatiser les procédures judiciaires et prévoir les récidives. Selon nous, le recours aux technologies intelligentes pour optimiser le travail de la police, la justice pénale et l’application de la loi contribue à la mise en place d’un « système pénal intelligent » ( smart criminal justice ). Cependant, toute utilisation des technologies n’est pas « intelligente » ( intelligent ou smart ) en soi. Au travers d’une analyse de la littérature, nous explorons la signification du terme « intelligence » d’un point de vue descriptif et normatif, afin d’établir un catalogue de critères déterminants. Nous avons établi que l’utilisation des technologies constitue une condition préalable, et identifié l’efficience, l’efficacité et la participation comme critères normatifs pour l’évaluation de toute initiative intelligente dans le secteur public. Compte tenu des particularités du système pénal, à ces critères peuvent s’ajouter des exigences de légalité, d’égalité et de transparence. En somme, cet article présente et examine des principes applicables à l’évaluation de l’utilité et de la légitimité des innovations techniques dans le système pénal. Le catalogue présenté ici permettra aux praticiens et aux décideurs de déterminer dans quels cas l’utilisation des technologies en matière de justice pénale est réellement intelligente et, plus important, dans quels cas elle ne l’est pas. Remarques à l’attention des praticiens Les technologies de pointe, qui sont de plus en plus utilisées dans le secteur public en général et dans le système pénal en particulier, sont à la fois sources d’opportunités et de risques importants. Pour que le système pénal soit considéré comme « intelligent », l’utilisation des technologies doit être conforme à des principes normatifs. Cet article présente une liste de critères normatifs permettant d’évaluer si une technologie est utilisée intelligemment. Les praticiens sont invités à se servir de ce catalogue comme d’un guide pour l’acquisition, la mise en œuvre et l’évaluation des technologies.
Bifurcation analysis in a discrete predator–prey model with herd behaviour and group defense
Authors: Xia Jie , Li Xianyi 
Published: June 2023

<abstract><p>In this paper, we utilize the semi-discretization method to construct a discrete model from a continuous predator-prey model with herd behaviour and group defense. Specifically, some new results for the transcritical bifurcation, the period-doubling bifurcation, and the Neimark-Sacker bifurcation are derived by using the center manifold theorem and bifurcation theory.	Novelty includes a smooth transition from individual behaviour (low number of prey) to herd behaviour (large number of prey). Our results not only formulate simpler forms for the existence conditions of these bifurcations, but also clearly present the conditions for the direction and stability of the bifurcated closed orbits. Numerical simulations are also given to illustrate the existence of the derived Neimark-Sacker bifurcation.</p></abstract>
Une migration ignorée.
Authors: Airiau Paul 
Published: June 2023

À partir du début du xixe siècle, la Rome pontificale attire de plus en plus d’étudiants ecclésiastiques, venant d’abord d’Europe, puis rapidement des Amériques, et du reste du monde à partir des années 1960. Cette croissance correspond à la romanisation du catholicisme, qu’elle alimente en retour. Elle est aussi due à la création de nouvelles universités ecclésiastiques qui cherchent à attirer de nouveaux étudiants. Les études à Rome facilitent les carrières ecclésiastiques, en procurant aux étudiants un capital utile à l’ascension dans la hiérarchie catholique et en les acculturant à la romanité.
Les « bystanders » en Bosnie‑Herzégovine pendant la guerre des années 1990
Authors: Lučić Iva 
Published: June 2023

Les spécialistes du comportement continuent de se débattre avec la définition et le rôle du « spectateur » dans les périodes de violence de masse. En prenant la guerre en Bosnie-Herzégovine comme étude de cas, la professeure Iva Lučić analyse les crimes commis et les acteurs définis comme des spectateurs ; elle aborde également la question de savoir si le terme bystander (spectateur) s’applique à l’étude de cas de la Bosnie-Herzégovine.
Development of a Liquid Chromatography and High-Resolution and -Accuracy Mass Spectrometry Method to Evaluate New Biotherapeutic Entity Processing in Human Liver Lysosomes
Authors: Colangelo Gabriele Sergio , Di Ianni Andrea , Cowan Kyra , Riccardi Sirtori Federico , Barbero Luca Maria 
Published: June 2023

Abstract
Biotherapeutic immunogenicity remains a great challenge for researchers because multiple factors trigger immune responses. Predicting and assessing the potential human immune response against biological drugs could represent an impressive breakthrough toward generating potentially safer and more efficacious therapeutic proteins. This article describes an in vitro assay that can contribute to evaluating the potential immunogenicity of biotherapeutics by focusing on lysosomal proteolysis. We selected human liver lysosomes (hLLs) from four different donors as a surrogate in vitro model instead of APC lysosomes because they are a ready-to-use lysosomal source. To assess the biological comparability of this surrogate to APC lysosomal extract, we compared the proteome content of hLLs with literature data of lysosomal fractions extracted from murine bone marrow and human blood-derived dendritic cells. Then we tested infliximab (IFX; Remicade) under different proteolytic conditions using liquid chromatography and high-resolution and -accuracy mass spectrometry to better define the degradation kinetics inside the lysosomes. hLLs revealed similar enzymatic content compared with human and murine dendritic cell lysosomes. Degradation assays demonstrated that our liquid chromatography and high-resolution and -accuracy mass spectrometry method could identify both the intact protein and the peptides resulting from proteolysis with high specificity and resolution. The rapid and easy assay described in this article can be extremely useful for evaluating the immunogenic risk associated with therapeutic proteins. In addition, this method can complement information from MHC class II–associated peptide proteomics assays and other in vitro and in silico techniques.
Role of IL-27 in HSV-1–Induced Herpetic Stromal Keratitis
Authors: Antony Ferrin , Pundkar Chetan , Sandey Maninder , Mishra Amarjit , Suryawanshi Amol 
Published: June 2023

Abstract
Herpetic stromal keratitis (HSK) is a painful and vision-impairing disease caused by recurrent HSV-1 infection of the cornea. The virus replication in the corneal epithelium and associated inflammation play a dominant role in HSK progression. Current HSK treatments targeting inflammation or virus replication are partially effective and promote HSV-1 latency, and long-term use can cause side effects. Thus, understanding molecular and cellular events that control HSV-1 replication and inflammation is crucial for developing novel HSK therapies. In this study, we report that ocular HSV-1 infection induces the expression of IL-27, a pleiotropic immunoregulatory cytokine. Our data indicate that HSV-1 infection stimulates IL-27 production by macrophages. Using a primary corneal HSV-1 infection mouse model and IL-27 receptor knockout mice, we show that IL-27 plays a critical role in controlling HSV-1 shedding from the cornea, the optimum induction of effector CD4+ T cell responses, and limiting HSK progression. Using in vitro bone marrow–derived macrophages, we show that IL-27 plays an antiviral role by regulating macrophage-mediated HSV-1 killing, IFN-β production, and IFN-stimulated gene expression after HSV-1 infection. Furthermore, we report that IL-27 is critical for macrophage survival, Ag uptake, and the expression of costimulatory molecules involved in the optimum induction of effector T cell responses. Our results indicate that IL-27 promotes endogenous antiviral and anti-inflammatory responses and represents a promising target for suppressing HSK progression.
Comparative evaluation of the efficacy of nicotine chewing gum and nicotine patches as nicotine replacement therapy using salivary cotinine levels as a biochemical validation measure
Authors: Sivasankari T , Sankaran Avudaiappan , Murugappan Senthil , Subramanyam Veni , Subramanian Balanehru , Reddy RC Jagat , Vandana S 
Published: June 2023

ABSTRACT

Background:
Nicotine replacement therapy (NRT) and habit cessation counseling are considered the mainstay treatment for high nicotine dependence smokers. However, adherence to NRT is very poor. Among the NRTs, nicotine gums and nicotine patches are the most widely available. This study mainly evaluates the efficacy of nicotine gum and nicotine patches as NRT using salivary cotinine levels as a biochemical validation measure.

Materials and Methods:
A cross-sectional study was conducted on 72 known smokers who were willing to receive nicotine replacement therapy for cessation of smoking habits. The sample was divided into two groups: Group 1 tobacco smokers were offered nicotine chewing gum, and group 2 tobacco smokers were offered nicotine patches. Both groups received treatment for 12 weeks. At baseline and at the end of the trial period, the saliva samples were analyzed for cotinine levels using an enzyme-linked immunosorbent assay (ELISA). The severity of smoking was assessed using the Fagerstrom Test for Nicotine Dependence (FTND).

Results:
The quit rate was higher in the nicotine patch group compared with the nicotine gum group. On comparison of week one vs week twelve in the nicotine group nicotine gum group showed (CI: 18.10 to 13.83) and in the patch group (CI: 7.754 to 6.56) with P < 0.001. The pre- and post-cotinine estimation was significantly reduced for nicotine patches compared with nicotine gums, and patient compliance also yielded better results for nicotine patches.

Conclusion:
This study depicts that nicotine patches were better adhered to in comparison with nicotine gums, and salivary cotinine level is an effective biochemical validation measure.
Disability and quality of life in patients with treatment-resistant schizophrenia on long- term clozapine therapy
Authors: Nandakumar Dhandapani , Ganesh Ragul , Deb Koushik S. , Jain Raka , Sood Mamta 
Published: June 2023

ABSTRACT

Objectives:
To assess disability and quality of life (QOL) in treatment resistant schizophrenia (TRS) on long term clozapine therapy and assess their correlation with positive, negative and cognitive symptoms.

Methodology:
Disability and QOL in forty patients with TRS (as per modified Kane’s criteria) were assessed using World Health Organization Disability Assessment Schedule 2.0 and World Health Organization Quality of Life–BREF. Scale for assessment of positive symptoms, scale for assessment of negative symptoms and Addenbrooke’s cognitive examination-III were used to assess positive, negative and cognitive symptoms. Medication adherence rating scale assessed medication adherence.

Results:
Disability and QOL correlated significantly with medication adherence, negative and cognitive symptoms but not with positive symptoms. Subgroup analysis revealed significant difference between medication adherence (good vs poor) and cognitive (impairment vs non-impairment) groups.

Conclusion:
Negative and cognitive symptoms, and medication adherence correlated with disability and QOL.
Los Derechos Humanos, signos del Reino. Una reflexión desde Ignacio Ellacuría
Authors: Castellón Martín José Joaquín 
Published: June 2023

Este artículo intenta mostrar la intrínseca unión que se da entre experiencia de fe cristiana y promoción de los derechos humanos. El autor que se escoge como guía en este problema es Ignacio Ellacuría, como reconocimiento a su aportación a la reflexión sobre fe y justicia, cercano el 30 aniversario de su asesinato. El signo de los derechos humanos nos llama a ir transformando toda la realidad de la Iglesia. Tanto en su relación con el mundo, como en su propia configuración interna.
Efecto edad de alpacas huacaya en peso vivo, carne fresca, deshidratada, humedad, proteína, grasa y ceniza criadas en Pachacayo, Junín-Perú
Authors: Unchupaico Payano Ide , Vásquez Caycedo Aylas Moisés , Tapia Luján Luis Ernesto , Quispe Eulogio Carlos , Ancco Gómez Edith 
Published: June 2023

Objetivo: Determinar el efecto de la edad en alpacas Huacaya en peso vivo, rendimiento de carne, carne deshidratada y análisis proximal humedad, proteína, grasa y ceniza, criados en la SAIS Túpac Amaru en la sierra de la región Junín, resultados: para los pesos vivos promedio se hallaron diferencias significativas por edades (p > 0.05). En el peso de carne promedio se hallaron diferencias significativas por edades (p > 0.05). En el peso de carne deshidratada promedio se hallaron diferencias significativas por edades (p > 0.05). La humedad en charqui promedio fue 13.69 ± 1.57 %, no hallando diferencias significativas. La proteína promedio fue 47.73 ± 5.21 % no hallando diferencia significativa. La grasa promedio fue 3.33 ± 1.59 % no hallando diferencia significativa. La ceniza en promedio fue 13.96 ± 1.62 %; no hallando diferencia significativa. Concluyendo que la edad de las alpacas Huacaya influyen significativamente en el peso vivo, carne fresca y deshidratada, pero no en la humedad, proteínas, grasa y ceniza de la carne deshidratada.
Tinjauan Yuridis terhadap Pengadaan Tanah bagi Pelaksanaan Pembangunan Infrastruktur Jalan Tol Medan-Binjai
Authors: Zamharirah Zamharirah , Syahputra Akmaluddin 
Published: June 2023

Toll roads and other forms of infrastructure in Indonesia are highly dependent on land availability. Most of this is impacted by the way that the object of land obtaining is local area land that has been given over privileges, for the most part as confirmed and uncertified property freedoms. acquisition roads must also have their rights protected because land scarcity has always been a major obstacle to Indonesia's infrastructure development. Naturally, difficulties in acquiring land for infrastructure development may impede Indonesia's economic expansion. When land acquisition is carried out, the idea of legal rights to land and the significance of land to human life are taken into consideration. The 16.8-kilometer Medan-Binjai expressway framework advancement project is one of the Public Key Undertaking's activities. The normative juridical research method is used in this study, which looks at secondary data or library materials like laws and regulations, legal theories, and leading legal scholars' opinions. This exploration utilizes a subjective methodology, which is an examination that produces clear information investigation, in particular what the respondents state recorded as a hard copy or orally and furthermore genuine way of behaving, which is endlessly concentrated in general. While normative legal research with a qualitative approach is used in this study, field data results are also used.
Keywoords: infrastructure, normative legal research, toll roads
An Exploratory Study of Factors Affecting Research Productivity in Higher Educational Institutes Using Regression and Deep Learning Techniques
Authors: Helali Rasha G. Mohammed 
Published: June 2023

Higher education is grappling with challenges from globalization. The competition between worldwide universities depends not only on the availability of infrastructure and faculty members’ teaching quality but also on their research performance. The research produced by faculty members has a significant impact on a university’s standing, ability to acquire funds, and ability to enroll both domestic and international students. The objective of this paper is to identify factors affecting scientific research productivity in selected higher educational institutes. The paper reports the views of academic staff from different educational institutes on such issues as the determinants of research performance. A quantitative analysis approach, including correlation and regression, in addition to deep learning, was utilized to achieve the aim of the paper. The findings of this research demonstrate that the support of academic institutes for enhancing research and providing facilities and funds for such purpose has a great impact on research performance. The allocation of hours of scientific research to the faculty member also had a positive impact on the improvement of scientific research. Linking career promotion and scientific research encourages faculty members to publish more papers. Moreover, the level of qualification for faculty members has a great impact on their rate of publishing papers.

Received: 13 January 2023 | Revised: 2 June 2023 | Accepted: 9 June 2023

Conflicts of Interest
The author declares that she has no conflicts of interest to this work.

Data Availability Statement
Data sharing is not applicable to this article as no new data were created or analyzed in this study.

Author Contribution Statement
Rasha G. Mohammed Helali: Conceptualization, Methodology, Software, Validation, Formal analysis, Investigation, Resources, Data curation, Writing - original draft, Writing - review & editing, Visualization, Supervision, Project administration.