bluuebunny/crossref_metadata_2025_split huggingface dataset:
Simulated circulation and particle trajectory analysis related to the oil spill event in the Karawang Coastal Waters
Authors: Azzahrawaani A , Hartanto M T , Naulita Y , Apriansyah  
Published: February 2023

Abstract
The Karawang waters are situated at the north coast of West Java Province, where the wind-driven monsoonal current controls significantly the dispersion of oil spill. Here accident of oil spill was happened on 12 July 2019. The present study aims to simulate seasonal circulation and particle trajectory analysis related to oil spill dispersion, by performing a fine-resolution 1/96° coastal circulation model of CROCO. The model is validated SST (Sea Surface Temperature) detected form satellite, sea level, and surface current with high correlation (corr.>0.86). The Sentinel-1A imagery determined initial position of oil spill. Seasonal reversal currents are reproduced well by the model, consistence with past studies. The westward flows along the northern coastal area during the southeast monsoon (SEM) bring colder and saltier seawater. In contrast, the eastward flows during the northwest monsoon period, associated with warmer and fresher seawater. The massless particles related to oil spill dispersions are advected by the current westward along the coastal area. About one week after the accident, the oil spill closed to the Tanjung Karawang waters, where particle trajectories overlay with the observed Sentinel imagery. The model suggested that on 24 July 2019, particle trajectories released from oil spill accident arrived offshore Jakarta Bay.
Growth performance and blood figures of African catfish (Clarias sp.) fed with marine fungal fermented feed
Authors: Ekasari J , Achmadi F F , Isti’anah I , Tarman K 
Published: February 2023

Abstract
This study examined the impact of marine fungal fermented feed at various concentrations on the growth and blood profiles of African catfish Clarias sp.. Catfish with an average body weight of 0.74 ± 0.01 g were raised in an aquarium that measured 30 cm x 45 cm x 30 cm and contained 25 L of water. The feed was not fermented in this study (control), and the feed was fermented with marine fungi at various concentrations (using 0.5%, 1%, 2%, and 4% extract marine fungi). At 8:00 am, 12:00 pm, and 16:00 pm, fish were fed three times a day until they were completely satisfied. The results showed that feeding juvenile catfish marine fungal fermented diet resulted in significantly higher growth performance. The larger final biomass, faster growth, and lower feed conversion ratio were used to examine this. The generation of red blood cells in fish fed with fermented diets was higher and better than the control treatment, according to the results of the blood profile of catfish (P 0.05).
Ultrasound-assisted depolymerization of carrageenan from Kappaphycus alvarezii hydrolized by a marine fungus
Authors: Tarman K , Zuhair M W , Uju  , Pari R F 
Published: February 2023

Abstract

Kappaphycus alvarezii is a species of red seaweed that produces kappa-carrageenan. Carrageenan is a polysaccharide containing D-galactose and 3,6-anhydrogalactose units which linked by α-1,3 and β-1,4 glycosidic bonds. The study aimed to determine the optimal ultrasonication time in the carrageenan depolymerization process. In this study the hydrolysis process of K. alvarezii to obtain the carrageenan was carried out biologically using a marine fungus RS6A. Viscosity of the carrageenan was measured using Brookfield viscometer, which was then used to calculate the molecular weight by Mark-Houwink equation. The carrageenan’s viscosity and molecular weight values varied between 3.73-6.13 cP and 35.58-52.15 kDa, and had an inverse correlation with the ultrasonication time. These results indicated that ultrasonication was effective in reducing molecular weight in the depolymerization process. The selected treatment was obtained by ultrasonication for 30 minutes with conformity to standards of carrageenan according to SNI 8391: 2017 and FAO (2014).
Banggai cardinalfish (Pterapogon kauderni) monitoring in Bokan Kepulauan (2017-2021) highlights the need for the “BCF Garden” approach
Authors: Ndobe S , Serdiati N , Gani A , Walalangi J Y , Moore A M 
Published: February 2023

Abstract
The Banggai cardinalfish Pterapogon kauderni is a restricted range marine fish classified as Endangered in the International Union for Conservation of Nature Red List. Traded as an ornamental fish, the Banggai cardinalfish (BCF) is of national and international conservation concern. The “BCF Garden” concept aims to replenish depleted BCF stocks through community-based habitat and microhabitat rehabilitation. Under the National Action Plan for Banggai cardinalfish conservation, selected BCF populations have been monitored annually since 2017. Eight endemic BCF populations in the Bokan Kepulauan District, Banggai Laut Regency, Central Sulawesi Province, were monitored using a standardized belt transect method in 2017, 2018, 2019, and 2021. Data were collected on BCF abundance, size/age structure and microhabitat association, and critical microhabitat abundance (sea urchins, mainly Diadema and sea anemones). Despite the inter-site variation, overall abundance declined significantly for BCF (p = 0.02) and sea urchins (p=0.02). Total counts of BCF (4646) and urchins (498) in 2021 were 31% and 11%, respectively, of 2017 values (4921 and 4460); sea anemone count increased (61 to 87) but remained well below historical abundance levels. These results confirm the need for targeted measures to promote the recovery of BCF populations in Bokan Kepulauan. The holistic BCF Garden approach is recommended, especially at sites where Diadema urchins are heavily exploited.
Optimizing Tilapia Biofloc Technology Systems and Its Economic Profitability on Industrial Scale in Indonesia
Authors: Nugroho E , Kristanto A H , Pamungkas W , S Dewi R R S P , Rifaldi M 
Published: February 2023

Abstract
One of the technologies that can produce a high number of fish in limited land and water is biofloc. Adapting biofloc technology in Indonesia from laboratory to industrial scale requires several improvements. This study aims to optimize biofloc technology and to reduce production costs. A series of research activities to increase the productivity of tilapia by biofloc technology have been carried out using superior seeds variety, proper application of stocking densities, type and volume of tank/pond, and the seed size at the stocking. Feed efficiency, productivity, survival rate, specific growth rate, and economic parameters were observed. Using tilapia superior seed can increase biomass by 4% compared to Nirwana II tilapia variety. The best seed density that can be used is 75-80 fish/m3, it is related to the appropriate type or volume of the round tank, which is 10 m3. The correlation value (R2) between the size of the initial seed and the observed parameters were 0.9439 (specific weight gain rate); 0.5841 (feed efficiency); 0.4880 (productivity) and 0.4789 (survival rate). Optimization of biofloc technology can save production costs up to 38.41 %. The value of the R/C ratio is 2.03.
Investigation of the optimal parameters for butt joints in a friction stir welding (FSW) process with dissimilar aluminium alloys
Authors: Harachai Komsak , Prasomthong Suriya 
Published: February 2023

Abstract
Aluminum alloys are used in the modern automotive industry because they are lightweight. However, it is establised that conventional fusion welding processes affect weld performance. In this study, friction stir welding (FSW), also known as solid-state welding, was used to weld dissimilar aluminum alloys, AA6061-T6 and AA5083 plates. Response surface methodology based on Box-Behnken design (BBD) was used to investigate the appropriate process parameters. In this study, the effects of rotation speed (S), welding feed rate (f), and work angle (θ) were investigated. These three factors were examined at three levels over 17 experimental runs. The design was used to conduct experiments and develop mathematical regression models. Variance analysis was performed to examine the adequacy of the developed models. Finally, the effects of the process parameters on the mechanical properties of welded alloyes were investigated using mathematical models based on the macrostructure, microstructure, chemical composition, and fracture characteristics of the joints using SEM. The investigation found that the optimum welding parameters are a rotational speed of 777 rpm, welding speed of 44 mm min−1, and a work angle of 0.75°. Furthermore, the results confirm that the mathematical models and experiments are consistent.
Identification of aminobenzoic acids as selective inhibitors of the N-terminal phosphatase of soluble epoxide hydrolase
Authors: Kihara Yasuhiro , Nishimura Erina , Kanai Chisato , Kitano Yoshikazu , Suzuki Eriko , Hasumi Keiji 
Published: February 2023

ABSTRACT
Soluble epoxide hydrolase (EC 3.3.2.10) is a key enzyme in the regulation of inflammation and metabolism, whereas, the role of its N-terminal phosphatase activity (N-phos) has been poorly understood because of a lack of selective inhibitors. Here we report 4-aminobenzoic (Ki 15.3 µm) and 3-amino-4-hydroxy benzoic acid (Ki 11.7 µm) as selective competitive inhibitors of N-phos.
Coronavirus Immunotherapeutic Consortium Database
Authors: Mahita Jarjapu , Ha Brendan , Gambiez Anais , Schendel Sharon L , Li Haoyang , Hastie Kathryn M , Dennison S Moses , Li Kan , Kuzmina Natalia , Periasamy Sivakumar , Bukreyev Alexander , Munt Jennifer E , Osei-Twum Mary , Atyeo Caroline , Overton James A , Vita Randi , Guzman-Orozco Hector , Mendes Marcus , Kojima Mari , Halfmann Peter J , Kawaoka Yoshihiro , Alter Galit , Gagnon Luc , Baric Ralph S , Tomaras Georgia D , Germann Tim , Bedinger Daniel , Greenbaum Jason A , Saphire Erica Ollmann , Peters Bjoern 
Published: February 2023

Abstract
The coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has seen multiple anti-SARS-CoV-2 antibodies being generated globally. It is difficult, however, to assemble a useful compendium of these biological properties if they are derived from experimental measurements performed at different sites under different experimental conditions. The Coronavirus Immunotherapeutic Consortium (COVIC) circumvents these issues by experimentally testing blinded antibodies side by side for several functional activities. To collect these data in a consistent fashion and make it publicly available, we established the COVIC database (COVIC-DB, https://covicdb.lji.org/). This database enables systematic analysis and interpretation of this large-scale dataset by providing a comprehensive view of various features such as affinity, neutralization, in vivo protection and effector functions for each antibody. Interactive graphs enable direct comparisons of antibodies based on select functional properties. We demonstrate how the COVIC-DB can be utilized to examine relationships among antibody features, thereby guiding the design of therapeutic antibody cocktails.
Database URL https://covicdb.lji.org/
Biology and physiology ofHanseniaspora vineae: metabolic diversity and increase flavour complexity for food fermentation
Authors: Carrau Francisco , Dellacassa Eduardo , Boido Eduardo , Medina Karina , Valera Maria Jose , Fariña Laura , Perez Gabriel , Martin Valentina , Alvarez-Valin Fernando , Balestrazzi Lucia 
Published: February 2023

AbstractApiculate yeasts belonging to the genus Hanseniaspora are predominant on grapes and other fruits. While some species, such as Hanseniaspora uvarum, are well known for their abundant presence in fruits, they are generally characterized by their detrimental effect on fermentation quality because the excessive production of acetic acid. However, the species Hanseniaspora vineae is adapted to fermentation and currently is considered as an enhancer of positive flavour and sensory complexity in foods. Since 2002, we have been isolating strains from this species and conducting winemaking processes with them. In parallel, we also characterized this species from genes to metabolites. In 2013, we sequenced the genomes of two H. vineae strains, being these the first apiculate yeast genomes determined. In the last 10 years, it has become possible to understand its biology, discovering very peculiar features compared to the conventional Saccharomyces yeasts, such as a natural and unique G2 cell cycle arrest or the elucidation of the mandelate pathway for benzenoids synthesis. All these characteristics contribute to phenotypes with proved interest from the biotechnological point of view for winemaking and the production of other foods.
Simultaneous Quantitative Analysis of Salmeterol and Fluticasone in Inhalation Spray Using HPLC and a Fast Spectrophotometric Technique Combined with a Time Series Neural Network and Multivariate Calibration Methods
Authors: Valizadeh Maryam , Ameri Braki Zahra , Smiley Erfan , Arghand Arezoo , Dastafkan Poriya 
Published: February 2023

Abstract

Background
Chromatographic methods have been used for the simultaneous determination of salmeterol (SMT) and fluticasone (FLU). The methods take a lot of analysis time, need sample pre-treatment and large amounts of solvents, and are costly.

Objective
The aim of this paper was to propose a simple, quick, and low-cost method for the determination of SMT and FLU using a time series neural network and multivariate calibration methods, including partial least-squares (PLS) and principal component regression (PCR).

Methods
The simultaneous spectrophotometric determination of SMT and FLU in binary mixtures and anti-asthma spray was performed by applying multivariate calibration methods and an intelligent approach.

Results
The coefficient of determination (R2) of the time series neural network was obtained: 1 and 0.9997 for SMT and FLU, respectively. The mean recovery of PLS was found to be 99.29% and 99.84% for SMT and FLU, respectively. Also, the mean recovery related to the PCR method was 102.05% and 103.72% for SMT and FLU, respectively.

Conclusion
The inhalation spray was assessed using HPLC and the results were compared with chemometrics methods via an analysis of variance (ANOVA) test.

Highlights
Intelligent and multivariate calibration methods were proposed. Simultaneous spectrophotometric determination of salmeterol and fluticasone was studied in an anti-asthma spray. HPLC as a reference method was performed and compared with chemometrics methods. Rapid, simple, low-cost, and accurate are the benefits of the proposed approaches.
Sequence architecture, depositional system evolution and controlling factors in a lacustrine basin: a case study from Changdi Area, Bohai Bay Basin, Eastern China
Authors: Cheng Yuhan , Wang Zhiwei , Liu Jingyan , Wu Qunhu , Yu Shina , Ma Xiao , Peng Dingliang , Zhang Yiyao 
Published: February 2023

AbstractThe Paleogene Shahejie and Dongying formations of the eastern Bohai Bay Basin contain &gt;500 m fluvial-deltaic deposits and &gt;600 m deltaic-lacustrine deposits, both of which are important for oil and gas exploration. This study aims to figure out the deposition system distribution within the sequence stratigraphy and predict the exploration target. Sequence boundaries are recognized by unconformities in the seismic profiles and abrupt changes in the well-logging curves (acoustic, spontaneous potential, natural gamma-ray and resistivity), and two second-order and five third-order sequences (SQs1, SQs3 in the Shahejie Formation and SQd1-SQd3 in Dongying Formation) are identified. Four types of depositional system and distribution are determined by well-logging profiles, cores, relative sand content and root-mean-square seismic attributes. The SQs3 sequence is predominantly fan deltas and lacustrine deposits, the SQs1 sequence is predominantly shallow lacustrine deposits, the SQd3 sequence is predominantly braided-river delta, semi-deep lacustrine, and turbidite fan, and the SQd2 sequence is predominantly braided-river delta deposits, whereas the SQd1 sequence is predominantly braided-river deposits. The controlling factors are determined by basin subsidence simulation and fossil data of biological palynology, indicating that tectonic activity is the main controlling factor in SQs3 and SQd3 while climate is the main controlling factor in the SQs1, SQd2 and SQd1 sequences. Combined with the physical properties of sandstone, it is concluded that the beach bar in the SQs1 sequence, turbidite fan in the SQs3 and SQd3 sequences, and thick sandstone in the SQd2 sequence are the important exploration targets.
Dynamic Covariance Matrix Estimation and Portfolio Analysis with High-Frequency Data
Authors: Jiang Binyan , Liu Cheng , Tang Cheng Yong 
Published: February 2023

Abstract
The covariance matrix associated with multiple financial returns plays foundational roles in many empirical applications, for example, quantifying risks and managing investment portfolios. Such covariance matrices are well known to be dynamic, that is, their structures change with the underlying market conditions. To incorporate such dynamics in a setting with high-frequency noisy data contaminated by measurement errors, we propose a new approach for estimating the covariances of a high-dimensional return series. By utilizing an appropriate localization, our approach is designed upon exploiting generic variables that are informative in accounting for the dynamic changes. We then investigate the properties and performance of the high-dimensional minimal-variance sparse portfolio constructed from employing the proposed dynamic covariance estimator. Our theory establishes the validity of the proposed covariance estimation methods in handling high-dimensional, high-frequency noisy data. The promising applications of our methods are demonstrated by extensive simulations and empirical studies showing the satisfactory accuracy of the covariance estimation and the substantially improved portfolio performance.
Intrathoracic lipoma of chest wall misdiagnosed as liposarcoma with malignant features based on radiological image and intraoperative findings
Authors: Koike Sachie , Miyazawa Masahisa , Kobayashi Nobutaka , Satomi Hidetoshi 
Published: February 2023

Abstract
Lipomas are common benign tumors, which are usually located in the subcutaneous tissue. It is relatively rare for lipoma to occur in the intrathoracic cavity, and it is clinically difficult to distinguish it from liposarcoma. We present the case of a 72-year-old man with a chest wall tumor preoperatively diagnosed as liposarcoma, with tumor enlargement with radiological image change to heterogenous and 18F-fluorodeoxyglucose positron emission tomography uptake. The tumor was resected along the chest wall, lung and diaphragm because of dense adhesions. The tumor was diagnosed as lipoma with fat necrosis and inflammatory changes.
Interstitial Cell Dysregulation in Allergic Contact Dermatitis: A Morphodynamic Study of Novel Interstitial Cell Telocytes
Authors: Zhu Zhaoxuan , Ma Qianhui , Meng Xiangfei , Pan Yuxue , Li Yanhua , Wang Jia , Liu Yue , Yang Ping 
Published: February 2023

AbstractAllergic contact dermatitis (ACD) is an occupation-dependent skin disease that afflicts humans with recurrent, non-specific episodes. Telocyte (TC) is a novel interstitial cell discovered in recent years and, together with fibroblasts, constitutes the predominant interstitial cell population in the skin. The purpose of this study was to investigate the morphodynamic changes of interstitial cells, especially TCs, in the skin during the development and treatment of ACD by histological and microscopic scientific methods. Hematoxylin-eosin staining, Masson staining, immunohistochemistry (IHC), immunofluorescence (IF), scanning electron microscopy (SEM), and transmission electron microscopy (TEM) were used to track morphodynamic changes in interstitial cells during the development and treatment in the ACD-involved skin induced by 2,4-dinitrochlorobenzene (DNCB). The results demonstrated that TCs were mainly present around dermal collagen fibers, perivascular (except dermal papillary vascular loop), and skin appendages, which expressed CD34+, Vimentin+, PDGFR-α+, and α-SMA−. The absence of TCs during ACD development and after ACD recovery causes dermal interstitial cell dysregulation. The special anatomical relationships between TCs, immune cells, and follicular stem cells were also revealed, suggesting their potential dermatitis-regulating function. In a nutshell, our results provide morphodynamic evidence for the process of ACD development and recovery and offer potential cytological ideas for ACD treatment.
Instrumental in Surgery
Authors: Casey Vincent J. , McNamara Laoise M. 
Published: February 2023

Objective:
To provide an informed understanding of existing energy-based surgical cutting technologies and aerosol-generating surgical procedures. We provide a perspective on the future innovation and research potential in this space for the benefit of surgeons, physicians, engineers, and researchers alike.

Background:
Surgery is a treatment for many medical conditions, the success of which depends on surgical cutting instruments that enable surgeons to conduct surgical procedures for tissue cutting and manipulation. Energy-based surgical cutting tools improve accuracy and limit unnecessary destruction of healthy tissues and cells, but can generate surgical smoke and aerosols, which can be handled using surgical smoke evacuation technology.

Methods:
A narrative review was conducted to explore existing literature describing the history and development of energy-based surgical instruments, their mechanisms of action, aerosol-generating medical procedures, surgical smoke and aerosols from aerosol-generating medical procedures, and the recommended mitigation strategies, as well as research on rapid biological tissue analyzing devices to date.

Conclusions:
Smoke evacuation technology may provide diagnostic information regarding tissue pathology, which could eliminate health concerns and revolutionize surgical accuracy. However, further research into surgical smoke is required to quantify the measurable risk to health it poses, the cutting conditions, under which it is generated and to develop advanced diagnostic approaches using this information.