bluuebunny/crossref_metadata_2025_split huggingface dataset:
Team assembly approach based in social modelling
Authors: Anaya Antonio R. , Letón Emilio , Luque Manuel 
Published: March 2023

Abstract
Team assembly is an important issue when collaborative or cooperative activities between people are carried out. In the educational context, it seems relevant to us to consider in the assembly process how students interact with others. Therefore, it is appropriate to carry out a process to model social behavior. In turn, the experts will be able to use the modeling information to establish the appropriate criteria to differentiate between assembly strategies according to the educational contexts. Our social behavior modeling process proposal is based on the information that can be extracted from the interactions and is guided by experts. We propose an approach divides into steps. Firstly, social network analysis metrics are used to study students’ social interactions. Secondly, a set of social interactions attributes are offered so that experts can organize them hierarchically. Thirdly a quantitative information on the students’ relationship that an influence diagram can infer due to the attributes hierarchically ordered. Once the modelling process is out, the qualitative information may be used to improve the team assembly. We describe in this paper two experiences where we have put it into practice our approach. The students made a peer review task. However, the pedagog-ical strategies that experts followed were different for each experience.
Differences of birds communities of levee forests in wetlands
Authors: Brarda Carolina Antonella , Manzano Adriana Silvina , Piña Carlos Ignacio , Frutos Antonio Esteban 
Published: March 2023

Abstract
Context.
The fluvial forests on the islands, called levee forests, have vertical vegetation stratification. This contributes to the structural complexity that allows the presence of a great bird diversity on island and among fluvial corridors.
Objectives.
The aim was to evaluate differences in the avifauna of levee forest. We hypothesized that birds make a differential use of the different types of levee forests, which is reflected in the bird assemblage structure of each forest type.
Methods.
The “Delta del Paraná” Ramsar site is a wetland of international importance. A comparative analysis of richness, abundance and diversity was conducted in the different levee forests using the point count method.
Results.
Three types of levee forest were obtained: open, intermediate and closed forests, according to the floristic composition, tree cover, and height of the herb stratum. A total of 85 bird species were recorded. The differences in birds communities structure were found among seasons, between sites and among forest types. We found the highest richness, abundance, and diversity values in open forests. These reveals the structural variation in the levee forests offer in their interior and show the microscale variation in forest wetlands, which have been considered a single homogeneous environmental unit in floodplains.
Conclusions.
The finding that open forests harbor the most heterogeneous environment in levee environments reflects the importance of microspatial-scale heterogeneity in landscape configuration and how this variation contributes to maintaining high biodiversity in fluvial wetlands for both avifauna as for the biota in general.
High expression of ZNF692 impairs overall survival in patients with colorectal cancer-analysis of immunohistochemical staining and bioinformatics data
Authors: ge xiaosong , Ge Xiaosong , Liu Fen , Liu Xiaoyuan , Gao Xiang , Mao Yong 
Published: March 2023

Abstract
Zinc finger protein 692 (ZNF692) promotes tumor progression as a potential oncogene, but its role in colorectal cancer (CRC) is not fully understood. We therefore carried out the present study to explore the correlation between ZNF692 expression and the progression of CRC. In this study, Tissue microarray and immunohistochemistry (IHC) staining was applied to detect the expression of ZNF692 protein in formalin-fixed, paraffin embedded (FFPE) tissues. The colorectal cancer data in TCGA database is analyzed and verified using R language. Our results showed that ZNF692 expression in CRC tissues was significantly upregulated compared with the matched normal tissues. (p < 0.05). Among 248 colorectal cancer tissues, 126 had high expression of ZNF692. In addition, there was a significant association between ZNF692 expression and age, M stage and histologic grade between the two groups, but not other clinical characteristics. Multivariate analysis showed that high expression of ZNF692 was an independent predictor of prognosis in colorectal cancer patients. The results of bioinformatics analysis also confirmed that the expression level of ZNF692 affects the prognosis of patients with CRC. In conclusion, our results suggest that the high expression of ZNF692 is associated with the poor prognosis and could be a novel biomarkers in colorectal cancer patients.
ELOVL2, a novel and potential tumor antigen guided mRNA vaccine development for retroperitoneal liposarcoma
Authors: Wang Zhenyu , Tao Ping , Fan Peidang , Wang Jiongyuan , Rong Tao , Zhou Yuhong , Lu Weiqi , Hong Liang , Ma Lijie , Zhang Yong , Tong Hanxing 
Published: March 2023

Abstract
Background
The exploration of lipid metabolism dysregulation may provide novel perspectives for retroperitoneal liposarcoma (RPLS). In our study, we aimed to investigate potential tumor antigen for mRNA vaccine development and facilitate further understanding of immune landscape in RPLS, through lipid metabolism-associated genes (LMAGs) based prognostic model.
Methods
Gene expression profiles and corresponding clinical information of 234 cases were enrolled from two public databases and the largest retroperitoneal tumor research center of East China, including cohort-TCGA (n = 58), cohort-GSE30929 (n = 92), cohort-FD (n = 50), cohort-scRNA-seq (n = 4) and cohort-validation (n = 30). Consensus clustering analysis was performed to identify lipid metabolism-associated molecular subtypes (LMSs). A prognostic risk model containing 13 LMAGs was established using LASSO algorithm and multivariate Cox analysis in cohort-TCGA. ESTIMATE, CIBERSORT, XCELL and MCP analyses were performed to visualize the immune landscape. WGCNA was used to identify three hub genes among the 13 model LMAGs, and preliminarily validated in both cohort-GSE30929 and cohort-FD. Moreover, TIMER was used to visualize the correlation between antigen-presenting cells and potential tumor antigens. Finally, single-cell RNA-sequencing (scRNA-seq) analysis of four RPLS and immunohistochemistry were performed in cohort-validation to check the discoveries of bioinformatics analysis.
Results
LMS1 and LMS2 were characterized as immune-infiltrated and -excluded tumors, with significant differences in molecular features and clinical prognosis, respectively. ELOVL2 was negatively correlated with antigen-presenting cells and identified as a potential tumor antigen for mRNA vaccine development. Furthermore, ELOVL2 was enriched in LMS2 with significantly lower immunoscore and unfavorable prognosis. Finally, a high-resolution dissection through scRNA-seq was performed in four RPLS, revealing the entire tumor ecosystem and validated previous findings.
Conclusions
The LMS subgroups and risk model based on LMAGs proposed in our study were both promising prognostic classifications for RPLS. ELOVL2 is a potential tumor antigen linking lipid metabolism to immune regulations for mRNA vaccine development against RPLS, specifically for patients with LMS2 tumors.
Machine-Driven Design and Dimensioning of NFV-Enabled MEC Infrastructure to Support Heterogeneous Latency-Critical Applications
Authors: Hiabeh Lina Abou , Yagoub Mustapha , Jarray Abdallah 
Published: March 2023

Abstract
Mobile edge computing (MEC) has recently been introduced as a key technology, emerging in response to the increased focus on new heterogeneous computing applications, resource-constrained mobile devices, and the long delay of traditional cloud data centers. Despite considerable research attention to understanding how the heterogeneous latency-critical application requirements can interact with a MEC system, there remains a dearth of literature on deploying a flexible MEC infrastructure at the mobile operator to meet the demands of an anticipated heterogeneous mobile traffic.
From a dual perspective, this paper addresses the design and dimensioning of a machine-driven Network Function Virtualization-enabled MEC infrastructure problem. The proposed approach leverages a neural network model, a subset of machine learning, to predict the number of service function chains (SFCs) required for the time-varying mobile traffic load and to proactively auto-scale the different types of virtual service instances. A Mixed-Integer Linear Program (MILP) is then employed to create a physical MEC system design by mapping the predicted virtual SFC networks to the MEC nodes while minimizing deployment costs. The numerical results demonstrate that the machine learning model achieves a high prediction accuracy of 95.6%, highlighting the added value of using the ML technique at the edge network. This approach reduces deployment costs while ensuring delay requirements for different latency-critical applications and high acceptance rates.
Grafting of electrically stimulated subventricular neural stem cells embedded in a nutritional hydrogel into the stroke cavity improved cell survival and behavioural recovery in mice
Authors: Gresita Andrei , Surugiu Roxana , Catalin Bogdan , Doeppner Thorsten R , Pirici Daniel , Daniela Calina , Coman Cristin , Hermann Dirk M , Popa-Wagner Aurel , Boboc Ianis KS 
Published: March 2023

Abstract

The major aim of stroke therapy is to stimulate brain repair and improve behavioral recuperation after cerebral ischemia. One option is to stimulate endogenous neurogenesis in the sub-ventricular zone (SVZ) and direct the newly formed neurons to the damaged area. However, only a small percentage of these neurons survive and, of those that do, many will not reach the damaged area possibly because the corpus callosum impedes the migration of SVZ-derived stem cells into the lesioned cortex. A second major obstacle to stem cell therapy is the strong inflammatory reaction induced by cerebral ischemia whereby the associated phagocytic activity of brain macrophages removes both therapeutic cells and/or cell-based drug carriers. In order to address these issues, neurogenesis was electrically stimulated in the SVZ followed by isolation of proliferating cells including the newly formed neurons which were subsequently mixed with a nutritional hydrogel. This mixture was then transferred to the stroke cavity of day 14 post-stroke mice. We found that the treated animals showed improved performance with behavioral tests including novel object, open field, hole board, grooming, and „time-to-feel’ the adhesive tape. Furthermore, immunostaining showed that the stem cell markers nestin and Mash1, found in stimulated SVZ, survived for 2 weeks following transplantation. These results clearly indicate that transplantation of committed SVZ stem cells combined with a protective nutritional gel, directly into the infarct cavity after the peak of stroke-induced neuroinflammation, represents a feasible approach to improve neurorestoration after cerebral ischemia.
Nondestructive Testing of Ultrasonic Welded Polymer-Based Composites Using Active Thermography Method
Authors: Tirband Hamed , Akbari Davood , Kalajahi Pouya Faraji , Mohammadian Milad 
Published: March 2023

Abstract
Ultrasonic welding is one of the most common methods for joining the polymer parts. It provides a rapid joining with a proper strength. Ultrasonic welding is also considered as a clean joining. This method is widely used in joining of thermoplastic parts. But, in order to weld the thermoset parts, a coupling layer shall be incorporated. This method occasionally is perfect because of voids and improper adhesion between to welded parts, leading to significant weld strength reduction. Consequently, application of a kind of NDT method could be useful for quality assurance of these parts. In this paper, active IR thermography is employed to nondestructively test of ultrasonically welded Glass Fiber Reinforced Plastics (GFRP). In order to study the weld microstructure, SEM analysis is performed. The results indicated that the IR thermography is capable to detect the existence of some defects in the welding zone. The Lap-shear tests indicate that the dimensions of the defect reduce the weld strength, significantly.
Duplex Baseband Signal Transmission Over Free Space Optical (FSO) Link Employing Carrier Reuse
Authors: Zaheer  
Published: March 2023

Abstract
With increasing IoT and a plethora of multimedia applications being used, there is an ever-increasing demand for bandwidth-intensive applications coupled with cost-effectiveness. Communication networks employing optical fiber had been de facto standard for such communication systems. The Optical Fiber network's high cost and man-hours required for laying demand wireless solutions. Therefore, an optimum and cost-effective duplex optical link for two channels baseband signal data transmission has been designed and validated using a single laser source. The link is designed for high data rate transmission between buildings within 1.5~2 km utilizing modular and low complexity. An optical link for 20 Gb/s duplex data transmission is designed using a single laser source. A transmission distance of 1.5 km has been achieved by providing a cost-efficient design with low complexity by utilizing differential quadrature phase shift keying (DQPSK) and On-Off Keying (OOK) modulation techniques. The design allowed us to reuse the downlink signal for the uplink transmission over free Space, thus eliminating the requirement for a separate laser at the other end. Each channel's transmission data rate was 10Gb/sec. At the former end, the DQPSK technique was employed for data modulation and the data was transmitted into free space. The data was then split at the latter end for downlink reception along with reusing the downlink received signal for uplink transmission to the former end utilizing the OOK modulation technique. The received data was compared with the transmitted one to verify and validate the system's accuracy through signal waveforms and BER (Bit Error Rate). Bit error rate (BER) curves and eye diagrams of the received uplink and downlink signal over a duplex transmission single fiber link are provided.
A comparison of management policies for referee appointments in European men’s football
Authors: Atan Tankut , Çavdaroğlu Burak , Yavuz Zühal Özcan 
Published: March 2023

Abstract

Purpose/Rationale: Referee appointments to football fixtures are made behind closed doors and only a handful of people in respective committees fully know what the policies governing these appointments are. Said appointment criteria include referees’ performances in recent matches but performance information such as the merit tables in the English Premier League are not open to the public. We investigate what the underlying management policies are in the highest football divisions in European men’s football.
Design/Methodology/Approach: To uncover the underlying appointment policies, we conduct a statistical analysis of the central referee appointments in several European men’s leagues in the five seasons from 2017 to 2022.
Findings: While we point out differences among the investigated leagues including the ‘Big Five, our analysis also shows that the officials may often be influenced by public opinions when taking those decisions.
Practical implications: A uniform appointment policy such as the one applied in La Liga can be more beneficial for referee development and fairness.
Research contribution: This research identifies differences in the appointment policies of various European men’s football leagues. Furthermore, a uniform appointment policy is suggested as a more useful appointment policy.
Two Simple and Effiffifficient Methods for a Class of Composite Functions Optimization
Authors: Wang Jinjiang , Hu Yanhong , Song Wen 
Published: March 2023

Abstract

In this paper, we focus on optimizing the optimization problems with the objective function formed as a sum of three terms: one is smooth, and the other two are simple convex functions with known structures. This problem
is challenging to solve, as the last two functions are both non-smooth and non-separable. Existing algorithms have high computational complexity and do not deal with large-size problems. To effiffifficiently solve this problem, we propose two ways to simplify it. One way is to introduce an additional variable to reformulate it as an equivalent two-block separable convex minimization model. Then we apply an approximate alternating direction method of multipliers(ADMM) to solve the equivalent model and establish a worst-case $O(1/k) $convergence rate for this method. Another way is to research the dual of the equivalent problem, and use an optimal fifirst-order method to solve the dual problem. Furthermore, we show that this method achieves a faster convergence rate of $O( 1/k ^2 )$. Finally, we also demonstrate an application called the fused Lasso problem.
Content of macro- and microelements in the plants of Artemisia annua L., A. ludoviciana Nutt. and A. austriaca L.
Authors: Кorablova Olha , Rakhmetov Jamal , Shanaida Mariia , Vergun Olena , Svydenko Ludmyla , Voitsekhivskyi Volodymyr 
Published: March 2023

The purpose of this study was to investigate mineral composition of the plants species Artemisia annua L., A. ludoviciana Nutt. and A. austriaca L.
Methods. Determination of the elemental composition of plant material was carried out by the X-ray fluorescence method.
Results. The content of mineral elements in plants depends on their individual ability to absorb elements from the soil and accumulate them in the roots, leaves and flowers. Plant samples of three species of wormwood were grown and studied during the flowering phase under conditions of introduction in M. M. Gryshko National Botanical Garden of National Academy of Sciences of Ukraine (NBG) during 2019–2022. The qualitative and quantitative content of different macro- and microelements in the soil and plants were investigated. It was shown that aerial parts of the investigated plants accumulate the most important elements for the plants life, such as – K, Fe, Cu, Zn and Mn. Mesoelements Ca and S are present in sufficient quantities also. Elements Nb, Y, Ti, V, Cr were detected in soil, but were not determined in plants. Only A. annua plants contains Ni and Se, while A. ludoviciana and A. annua plants contain Pb. The amount of toxic elements in plants did not exceed the maximum permissible concentrations for vegetable raw materials and food products.
Conclusion. Content of the main macro- and microelements was determined in the plants A. annua, A. ludoviciana and A. austriaca growing in NBG. The tendency of plants A. ludoviciana to accumulate high concentrations of iron in the roots and aerial part was observed. The obtained data will be useful for forecasting and evaluating the results of introduction of new promising species of the genus Artemisia, in breeding of new varieties of wormwood, to determine their pharmacological properties and to make a decision about the feasibility of using them in herbal tea and food products.
Дулааны 4 дүгээр Цахилгаан станцын үнсэн сангийн цацрагийн түвшин
Authors: М. Алтангэрэл  , M Н. Норов , Энхбат Н. , Цэрэнбалжид Ц. 
Published: March 2023

Энэхүү ажлаар дулааны 4-р цахилгаан станцын үнсэн сангийн дээжүүдэд гамма-спектрометрийн үнэмлэхүй арга ашиглан байгалийн цацраг идэвхт 226Ra, 232Th, 40K зэрэг изотопуудын хувийн идэвхийг тодорхойлж уг дүнгээ ашиглан радийн эквивалент идэвх, гамма цацрагийн агаар дахь шингэсэн тунгийн чадал, радоны эминацийн коэффициент зэргийг тооцолж үнсэн сангийн цацрагийн дэвсгэр түвшинг тогтоов.
Нарны идэвхт үзэгдлийн физик параметрүүдийг CFM аргаар тодорхойлоход үүсгүүрийн функцэд оптик зузааныг тооцох
Authors: Ч Мөнхжаргал , Д Батмөнх , Б Батбаяр 
Published: March 2023

We presented some results about the physical parameters, derived with the cloud model taking into account the dependence of source function on the optical depth for solar absorption features. The dependence of source function on the optical depth is represented in the form Sv(tv) = a( 1 + tn v). The parameter fitting is achieved by iterative Levcnberg-Marquardt method for nonlinear dependences. The results of calculation were compared with the results obtained with the constant source function. Our results show that the dependence of source function on the optical depth very strongly influences the values of the optical thickness. Therefore because of decrease of the optical thickness the arch-filament system became thin than with constant source function. From the calculation for the filaments shows that the greatly reduced values of N2 ,Ne, and vice versa, Te increases.
Богино цахилгаан пульсээр атомын долгион функцэд үүсэх хуйлрал
Authors: Зоригт  , Чулуунбаатар Алдармаа , Лочин Хэнмэдэх 
Published: March 2023

Энэ ажилд цахилгаан орны үйлчлэлээр 1S төлөвт орших устөрөгчийн атомын долгион функцийн хугацааны хувьсалыг судаллаа. Лазерын цахилгаан орны богино пульсээр атомыг өдөөх үед долгион функцийн хувьсалд ажиглагдах нэг онцгой үзэгдэл нь хуйлрал юм. Хуйлрал хэрхэн үүсч байгааг хугацаанаас хамааруулан дүрслэн харууллаа. Долгион функцийн фазын утгаас тоон аргаар градиент авч электроны хурдыг, хугацаагаар тухайн уламжлал авч локал энергийн гадаргыг дүрслэв.
Bacterial infection may trigger DRESS syndrome: an exceptional case of delayed hypersensitivity reaction occurring 22 months after allopurinol therapy
Authors: Souilem Ines , fatma zgolli , Lakhoua Ghozlane , Kastalli Sarrah , Daghfous Riadh , Aidli Sihem El 
Published: March 2023

Drug-induced hypersensitivity syndrome also known as DRESS syndrome is
considered as a severe and potentially life-threatening adverse drug
reaction. The pathogenesis of DRESS syndrome is still partially
understood. Prior research has implicated viral infection or
reactivation, specifically, human herpes viruses 6 and 7, Epstein-Barr
virus and cytomegalovirus.
We report a case of DRESS syndrome induced by allopurinol occurring 22
months after starting the treatment and which might have been triggered
by concomitant infections.
A 72-year-old man was put on allopurinol in February 2021. Twenty
months later, he was hospitalized for Klebsiella urinary tract infection
associated with erysipelas that had evolved well after two weeks of
antibiotherapy. On November 20, he presented a second episode of
Enterococcus faecalis urinary tract infection. On December 5, he
developed a pruritic maculopapular rash with fever (39.5°C). Skin
examination showed a generalized infiltrated erythematous maculopapular
eruption and facial edema. Complete blood counts showed total leucocyte
count at 10.6 × 10/µl with eosinophils at 1.58 ×
10/µl (14.9%). Histological findings were compatible
with DRESS syndrome. Allopurinol was stopped. Skin condition improved
within a month.
A prolonged delay between the start of treatment and the appearance of a
febrile rash should never exclude the diagnosis of Dress syndrome or
delay its management.