bluuebunny/crossref_metadata_2025_split huggingface dataset:
Translating community-based participatory research into broadscale sociopolitical change: insights from a coalition of women firefighters, scientists, and environmental health advocates
Authors: Ohayon Jennifer Liss , Rasanayagam Sharima , Rudel Ruthann A , Patton Sharyle , Buren Heather , Stefani Tony , Trowbridge Jessica , Clarity Cassidy , Brody Julia Green , Morello-Frosch Rachel 
Published: August 2023

Abstract
Background
We report on community-based participatory research (CBPR) initiated by women firefighters in order to share successful elements that can be instructive for other community-engaged research. This CBPR initiative, known as the Women Worker Biomonitoring Collaborative (WWBC) is the first we are aware of to investigate links between occupational exposures and health outcomes, including breast cancer, for a cohort of exclusively women firefighters.

Methods
In order to be reflective of the experiences and knowledge of those most intimately involved, this article is co-authored by leaders of the research initiative. We collected leaders’ input via recorded meeting sessions, emails, and a shared online document. We also conducted interviews (N = 10) with key research participants and community leaders to include additional perspectives.

Results
Factors contributing to the initiative’s success in enacting broadscale social change and advancing scientific knowledge include (1) forming a diverse coalition of impacted community leaders, labor unions, scientists, and advocacy organizations, (2) focusing on impacts at multiple scales of action and nurturing different, yet mutually supportive, goals among partners, (3) adopting innovative communication strategies for study participants, research partners, and the broader community, (4) cultivating a prevention-based ethos in the scientific research, including taking early action to reduce community exposures based on existing evidence of harm, and (5) emphasizing co-learning through all the study stages. Furthermore, we discuss external factors that contribute to success, including funding programs that elevate scientist-community-advocacy partnerships and allow flexibility to respond to emerging science-policy opportunities, as well as institutional structures responsive to worker concerns.

Conclusions
While WWBC shares characteristics with other successful CBPR partnerships, it also advances approaches that increase the ability for CBPR to translate into change at multiple levels. This includes incorporating partners with particular skills and resources beyond the traditional researcher-community partnerships that are the focus of much CBPR practice and scholarly attention, and designing studies so they support community action in the initial stages of research. Moreover, we emphasize external structural factors that can be critical for CBPR success. This demonstrates the importance of critically examining and advocating for institutional factors that better support this research.
Perioperative outcomes of robotic and laparoscopic surgery for colorectal cancer: a propensity score-matched analysis
Authors: Farah Emile , Abreu Andres A. , Rail Benjamin , Salgado Javier , Karagkounis Georgios , Zeh Herbert J. , Polanco Patricio M. 
Published: August 2023

Abstract
Background
Robotic colorectal surgery is becoming the preferred surgical approach for colorectal cancer (CRC). It offers several technical advantages over conventional laparoscopy that could improve patient outcomes. In this retrospective cohort study, we compared robotic and laparoscopic surgery for CRC using a national cohort of patients.

Methods
Using the colectomy-targeted ACS-NSQIP database (2015–2020), colorectal procedures for malignant etiologies were identified by CPT codes for right colectomy (RC), left colectomy (LC), and low anterior resection (LAR). Optimal pair matching was performed. “Textbook outcome” was defined as the absence of 30-day complications, readmission, or mortality and a length of stay < 5 days.

Results
We included 53,209 out of 139,759 patients screened for eligibility. Laparoscopic-to-robotic matching of 2:1 was performed for RC and LC, and 1:1 for LAR. The largest standardized mean difference was 0.048 after matching. Robotic surgery was associated with an increased rate of textbook outcomes compared to laparoscopy in RC and LC, but not in LAR (71% vs. 64% in RC, 75% vs. 68% in LC; p < 0.001). Robotic LAR was associated with increased major morbidity (7.1% vs. 5.8%; p = 0.012). For all three procedures, the mean conversion rate of robotic surgery was lower than laparoscopy (4.3% vs. 9.2%; p < 0.001), while the mean operative time was higher for robotic (225 min vs. 177 min; p < 0.001).

Conclusions
Robotic surgery for CRC offers an advantage over conventional laparoscopy by improving textbook outcomes in RC and LC. This advantage was not found in robotic LAR, which also showed an increased risk of serious complications. The associations highlighted in our study should be considered in the discussion of the surgical management of patients with colorectal cancer.
Exploring health insurance and knowledge of the ovulatory cycle: evidence from Demographic and Health Surveys of 29 countries in Sub-Saharan Africa
Authors: Zegeye Betregiorgis , Idriss-Wheeler Dina , Oladimeji Olanrewaju , Yaya Sanni 
Published: August 2023

Abstract
Background
Unplanned pregnancy continues to be a major public health concern in Sub-Saharan Africa (SSA). Understanding the ovulatory cycle can help women avoid unplanned pregnancy. Though a wide range of factors for ovulatory cycle knowledge in SSA countries has not been well assessed, the influence of health insurance on ovulatory cycle knowledge is largely unknown. As a result, we set out to investigate the relationship between health insurance enrollment and knowledge of the ovulatory cycle among women of childbearing age. This study aims to investigate the relationship between health insurance enrollment and knowledge of the ovulatory cycle among women of childbearing age in sub-Saharan Africa (SSA).

Methods
Demographic and Health Surveys (DHSs) data from 29 SSA countries were analyzed. The association between health insurance and ovulatory cycle knowledge was investigated using bivariate and multivariate multilevel logistic regression models among 372,692 women of reproductive age (15–49). The findings were presented as adjusted odds ratios (AOR) with 95% confidence intervals (CI). A p-value of 0.05 was considered statistically significant.

Results
The pooled result shows that the prevalence of knowledge of ovulatory cycle in the studied 29 SSA countries was 25.5% (95% CI; 24.4%-26.6%). Findings suggest higher odds of ovulatory cycle knowledge among women covered by health insurance (AOR = 1.27, 95% CI; 1.02–1.57), with higher education (higher-AOR = 2.83, 95% CI; 1.95–4.09), from the richest wealth quintile (richest-AOR = 1.39, 95% CI; 1.04–1.87), and from female headed households (AOR = 1.16, 95% CI; 1.01–1.33) compared to women who had no formal education, were from the poorest wealth quintile and belonged to male headed households, respectively. We found lower odds of ovulatory cycle knowledge among women who had 2–4 parity history (AOR = 0.80, 95% CI; 0.65–0.99) compared to those with history of one parity.

Conclusions
The findings indicate that the knowledge of the ovulatory cycle is lacking in SSA. Improving health insurance enrollment should be considered to increase ovulatory cycle knowledge as an approach to reduce the region's unplanned pregnancy rate. Strategies for improving opportunities that contribute to women’s empowerment and autonomy as well as sexual and reproductive health approaches targeting women who are in poorest quintiles, not formally educated, belonging to male headed households, and having high parity should be considered.
Comparison of thoracolumbar versus non-thoracolumbar osteoporotic vertebral compression fractures in risk factors, vertebral compression degree and pre-hospital back pain
Authors: Wang Feng , Sun Rui , Zhang Shao-Dong , Wu Xiao-Tao 
Published: August 2023

Abstract
Background
Thoracolumbar spine is at high risk of osteoporotic vertebral compression fractures (OVCF). This study aimed to identify the differences in risk factors, vertebral compression degree and back pain characteristics of thoracolumbar OVCF (TL-OVCF) and non-thoracolumbar OVCF (nTL-OVCF).

Methods
OVCF patients hospitalized in a spine center between June 2016 and October 2020 were retrospectively studied. Demographics, comorbidity, spine trauma, bone mineral density, duration of pre-hospital back pain, extent of vertebral marrow edema, and degree of vertebral compression of patients with nTL-OVCF were summarized and compared to those with TL-OVCF.

Results
A total of 944 patients with acute single-segment OVCF were included. There were 708 (75.0%) TL-OVCF located in T11-L2 and 236 (25.0%) nTL-OVCF in lower lumbar (L3-L5) and middle thoracic (T5-T10) spine. The female-male ratio was 4.1 in nTL-OVCF and differed not significantly from TL-OVCF. The middle thoracic OVCF were older and had higher comorbidity of coronary heart disease (21.3%) and cerebral infarction (36.3%) than TL-OVCF (12.1% and 20.6%). In nTL-OVCF the ratio of apparent spine trauma (44.9%) and pre-hospital back pain ≤ 1 week (47.5%) was lower than in TL-OVCF (66.9% and 62.6%). The T-score value of lumbar spine was − 2.99 ± 1.11, − 3.24 ± 1.14, − 3.05 ± 1.40 in < 70, 70–80, > 80 years old TL-OVCF and differed not significantly from nTL-OVCF. The lower lumbar OVCF had more cranial type of vertebral marrow edema (21.8%) and fewer concurrent lumbodorsal fasciitis (30.8%) than TL-OVCF (16.8% and 43.4%). In TL-OVCF the anterior–posterior vertebral height ratio was lower with back pain for > 4 weeks than for ≤ 1, 1–2, and 2–4 weeks. In nTL-OVCF the degree of vertebral compression differed not significantly with pre-hospital back pain for ≤ 1, 1–2, 2–4, and > 4 weeks.

Conclusions
Thoracolumbar spine has 2-folds higher risk of OVCF than non-thoracolumbar spine. Non-thoracolumbar OVCF are not associated with female gender, apparent spine trauma or poor bone mineral density, but tend to maintain the degree of vertebral compression and cause longer duration of pre-hospital back pain.
CT radiomics prediction of CXCL9 expression and survival in ovarian cancer
Authors: Gu Rui , Tan Siyi , Xu Yuping , Pan Donghui , Wang Ce , Zhao Min , Wang Jiajun , Wu Liwei , Zhao Shaojie , Wang Feng , Yang Min 
Published: August 2023

Abstract
Background
C-X-C motif chemokine ligand 9 (CXCL9), which is involved in the pathological processes of various human cancers, has become a hot topic in recent years. We developed a radiomic model to identify CXCL9 status in ovarian cancer (OC) and evaluated its prognostic significance.

Methods
We analyzed enhanced CT scans, transcriptome sequencing data, and corresponding clinical characteristics of CXCL9 in OC using the TCIA and TCGA databases. We used the repeat least absolute shrinkage (LASSO) and recursive feature elimination(RFE) methods to determine radiomic features after extraction and normalization. We constructed a radiomic model for CXCL9 prediction based on logistic regression and internal tenfold cross-validation. Finally, a 60-month overall survival (OS) nomogram was established to analyze survival data based on Cox regression.

Results
CXCL9 mRNA levels and several other genes involving in T-cell infiltration were significantly relevant to OS in OC patients. The radiomic score (rad_score) of our radiomic model was calculated based on the five features for CXCL9 prediction. The areas under receiver operating characteristic (ROC) curves (AUC-ROC) for the training cohort was 0.781, while that for the validation cohort was 0.743. Patients with a high rad_score had better overall survival (P < 0.001). In addition, calibration curves and decision curve analysis (DCA) showed good consistency between the prediction and actual observations, demonstrating the clinical utility of our model.

Conclusion
In patients with OC, the radiomics signature(RS) of CT scans can distinguish the level of CXCL9 expression and predict prognosis, potentially fulfilling the ultimate purpose of precision medicine.
Dual input neural networks for positional sound source localization
Authors: Grinstein Eric , Neo Vincent W. , Naylor Patrick A. 
Published: August 2023

AbstractIn many signal processing applications, metadata may be advantageously used in conjunction with a high dimensional signal to produce a desired output. In the case of classical Sound Source Localization (SSL) algorithms, information from a high dimensional, multichannel audio signals received by many distributed microphones is combined with information describing acoustic properties of the scene, such as the microphones’ coordinates in space, to estimate the position of a sound source. We introduce Dual Input Neural Networks (DI-NNs) as a simple and effective way to model these two data types in a neural network. We train and evaluate our proposed DI-NN on scenarios of varying difficulty and realism and compare it against an alternative architecture, a classical Least-Squares (LS) method as well as a classical Convolutional Recurrent Neural Network (CRNN). Our results show that the DI-NN significantly outperforms the baselines, achieving a five times lower localization error than the LS method and two times lower than the CRNN in a test dataset of real recordings.
Multiple positive solutions of fractional differential equations with improper integral boundary conditions on the half-line
Authors: Wang Ning , Zhou Zongfu 
Published: August 2023

AbstractThis paper investigates the existence of positive solutions for a class of fractional boundary value problems involving an improper integral and the infinite-point on the half-line by making use of properties of the Green function and Avery–Peterson fixed point theorem. In addition, an example is presented to illustrate the applicability of our main result.
The potential application of carbazole-degrading bacteria for dioxin bioremediation
Authors: Dinh Mai Thi Ngoc , Nguyen Van Thi , Nguyen Ly Thi Huong 
Published: August 2023

AbstractExtensive research has been conducted over the years on the bacterial degradation of dioxins and their related compounds including carbazole, because these chemicals are highly toxic and has been widely distributed in the environment. There is a pressing need to explore and develop more bacterial strains with unique catabolic features to effectively remediate dioxin-polluted sites. Carbazole has a chemical structure similar to dioxins, and the degradation pathways of these two chemicals are highly homologous. Some carbazole-degrading bacterial strains have been demonstrated to have the ability to degrade dioxins, such as Pseudomonas sp. strain CA10 và Sphingomonas sp. KA1. The introduction of strain KA1 into dioxin-contaminated model soil resulted in the degradation of 96% and 70% of 2-chlorodibenzo-p-dioxin (2-CDD) and 2,3-dichlorodibenzo-p-dioxin (2,3-DCDD), respectively, after 7-day incubation period. These degradation rates were similar to those achieved with strain CA10, which removed 96% of 2-CDD and 80% of 2,3-DCDD from the same model soil. Therefore, carbazole-degrading bacteria hold significant promise as potential candidates for dioxin bioremediation. This paper overviews the connection between the bacterial degradation of dioxins and carbazole, highlighting the potential for dioxin biodegradation by carbazole-degrading bacterial strains.
Ethical Considerations of Biopsies in Early-Stage Pancreatic Cancer
Authors: Bohan Riley P. , Riner Andrea N. , Herremans Kelly M. , George Thomas J. , Hughes Steven J. , Solberg Lauren B. 
Published: August 2023

PURPOSE The standard of care in resectable and borderline resectable pancreatic ductal adenocarcinoma (PDAC) has evolved to include neoadjuvant treatment before surgical resection. Current guidelines call for obtaining histologic tissue diagnosis via endoscopic ultrasound fine-needle aspiration before administration of neoadjuvant therapy, which differ from guidelines discouraging delay in surgical resection for a biopsy. MATERIALS AND METHODS Whether to proceed with treatment before a biopsy confirms that malignancy is a nuanced decision and includes considerations of physical and psychological risks entailed in both pursuing and forgoing a biopsy. RESULTS Accuracy of imaging and biopsy results, the presence of contributing clinical signs/symptoms, and the existing precedents of considering biopsies as waivable such as in scenarios with high clinical suspicion and primary surgical resection. CONCLUSION When considering the aspects of ethical medical practice including beneficence (doing good), nonmaleficence (avoiding harm), autonomy (allowing patients to make decisions about their care), and utilitarianism (doing the most good for the most people), analysis of whether guidelines guiding biopsies should continue to differ between resection and neoadjuvant treatments in PDAC is prudent.
Prolonged Endurance Exercise Increases Macrophage Content and Mitochondrial Respiration in Adipose Tissue in Trained Men
Authors: Sahl Ronni Eg , Patsi Ioanna , Hansen Mikkel Thunestvedt , Rømer Tue , Frandsen Jacob , Rasmusen Hanne Kruuse , Ingersen Arthur , Poulsen Steen Seier , Dela Flemming , Larsen Steen , Helge Jørn Wulff 
Published: August 2023

Abstract

Background
The aim of this study was to investigate the effect of prolonged endurance exercise on adipose tissue inflammation markers and mitochondrial respiration in younger and older men.

Methods
“Young” (aged 30 years, n = 7) and “old” (aged 65 years, n = 7) trained men were exposed to an exercise intervention of 15 consecutive days biking 7 to 9 hours/day at 63% and 65% of maximal heart rate (young and old, respectively), going from Copenhagen, Denmark to Palermo, Italy. Adipose tissue was sampled from both the gluteal and abdominal depot before and after the intervention. Mitochondrial respiration was measured by high-resolution respirometry, and adipose inflammation was assessed by immunohistochemical staining of paraffin embedded sections.

Results
An increased number of CD163+ macrophages was observed in both the gluteal and abdominal depot (P &lt; .01). In addition, an increased mitochondrial respiration was observed in the abdominal adipose tissue from men in the young group with complex I (CIp) stimulated respiration, complex I + II (CI+IIp) stimulated respiration and the capacity of the electron transport system (ETS) (P &lt; .05), and in the older group an increase in CIp and CI+IIp stimulated respiration (P &lt; .05) was found.

Conclusion
Overall, we found a positive effect of prolonged endurance exercise on adipose tissue inflammation markers and mitochondrial respiration in both young and old trained men, and no sign of attenuated function in adipose tissue with age.
Seismic investigation and upgrading of disused industrial buildings a case study
Authors: Longobardi Giovanna , Davino Antonio , Formisano Antonio 
Published: August 2023

In this paper, the evaluation of the seismic behaviour and the consolidation plan of a former industrial building are described.
After a short introduction regarding the value of industrial architecture, discovered only in the late ‘70s of the past century, and the necessity to intervene on this heritage, most of time abandoned, the case study has been introduced. It is a former tobacco industry placed in a small village in the outskirt of Salerno, in the South Italy.
Firstly, the historical evolution of the property has been reconstructed. Then, the main structural and architectonical features of the building have been illustrated. After this knowledge phase, the seismic behaviour has been evaluated with regard both to local and global mechanisms. Based on the obtained results, retrofitting operations have been hypothesized to allow for the new functionalization and the reuse of the building.
In conclusion, the effectiveness of the consolidating interventions has been demonstrated by repeating the pushover analyses, whose results have enabled the complete seismic upgrading of the former tobacco industry.
Innovative interactive technologies in the training of professional education specialists by means of digital technologies
Authors: Hevko Ihor , Siaonan Se , Hongwei Wu 
Published: August 2023

This article is devoted to the study and analysis of the role and influence of innovative interactive technologies in the training of professional education specialists using digital technologies. Digital technologies are becoming an increasingly integral part of our daily lives and impacting various fields, including education. The article examines the modern foreign and domestic experience of using modern innovative interactive technologies in the professional training of future vocational education specialists. The possibilities of implementing augmented reality (AR) and virtual reality (VR) to create immersive learning environments are described. Emphasis is placed on adaptive educational platforms that are able to individualize the educational process taking into account the personal needs and individual characteristics of students. The analysis of the influence of interactive technologies on the activity and interest of students, increasing the level of involvement and motivation to study was carried out. The advantages of these technologies in the training of specialists are analyzed, their impact on student motivation, understanding of complex concepts and the creation of interactive learning environments is noted. It highlights how the adaptability of learning platforms helps create personalized learning paths for each student, taking into account their needs and pace of learning. The experience of using innovative and interactive technologies in various fields, including education, science and technological development, is outlined.
The results of the study indicate the importance of integrating digital technologies into the educational process to achieve more effective learning and development of relevant skills among students of vocational education.
Out-of-hospital care for postpartum haemorrhage: a scoping review protocol
Authors: Soh Rachel , Silvestri Lucymarie , Pearce Anna , Pearce James 
Published: August 2023

Introduction Postpartum haemorrhage is an obstetric emergency with potential for rapid deterioration. It is one of the leading causes of maternal mortality worldwide. This risk is magnified in the resource-limited out-of-hospital setting, yet there is little knowledge regarding its management in these circumstances. Methods The JBI scoping review methodology will be used. A comprehensive search strategy will be adopted to identify sources of literature that fit the inclusion criteria. Data will be extracted and reported in accordance with current best practice standards. Discussion This protocol will provide the framework to guide the review in identifying the scope, depth and key concepts in the topic of interest, as well as to identify gaps in knowledge regarding out-of-hospital care of the patient with postpartum haemorrhage. Information gathered can help inform clinical practitioners and the development of clinical practice guidelines. Gaps identified can be used to guide and facilitate further research.