bluuebunny/crossref_metadata_2025_split huggingface dataset:
Molecular prevalence and associated infection risk factors of tick-borne protozoan and rickettsial blood pathogens in small ruminants
Authors: Abdelsalam Mennat-Allah , Felefel Wael , Fadl Sabreen , Bessat Mohamed 
Published: August 2023

Abstract
Background
Tick-borne blood pathogens cause highly pathogenic diseases, which are associated with substantial economic losses in ruminants. Despite this, epidemiological research on these pathogens remains neglected in many countries. This study initiated a regional epidemiological survey that included the detection of molecular prevalence, associated risk factors, and gene sequencing, combined with phylogenetic analysis, targeting the two main tick-borne blood protozoan and rickettsial pathogens of Babesia, Theileria, and Anaplasma that infect small ruminants. One hundred blood samples were collected from 76 sheep and 24 goats.

Results
Microscopic examination of Giemsa-stained blood films revealed that 73% of the samples were infected with at least one species of the three blood pathogenic organisms. Molecular diagnosis based on the 18 S rRNA for Babesia and Theileria species and the major surface protein 4 (msp4) for Anaplasma species, revealed that 43% of the small ruminants were infected with at least one of these pathogens. The animal’s sex was the most significant associated risk factor, with 49.4% of female animals infected compared with only 4% of male animals (P < 0.05). The open breeding system recorded the highest infection rate for tick-borne blood pathogens. Homology-based and phylogenetic analyses indicated that the specific isolate species were Babesia ovis (B. ovis), Theileria ovis (T. ovis), and Anaplasma ovis (A. ovis), with sequences showing significant identities with isolates from sheep, goats, and other animal species, and geographically diverse countries in Africa, Asia, and Europe, in addition to Egypt.

Conclusion
This was the first molecular evidence of B. ovis, T. ovis, and A. ovis infections in sheep and goat populations in the North Coast region of Egypt. More extensive studies are required to develop an epidemiological map of blood pathogenic organisms, while more effective control strategies are required to reduce the burden of tick-borne pathogens on small ruminants.
Association between the triglyceride glucose (TyG) index and the risk of acute kidney injury in critically ill patients with heart failure: analysis of the MIMIC-IV database
Authors: Yang Zewen , Gong Hongxia , Kan Fuqiang , Ji Ningning 
Published: August 2023

Abstract
Background
Insulin resistance (IR) can be effectively assessed using the dependable surrogate biomarker triglyceride-glucose (TyG) index. In various critical care contexts, like contrast-induced acute kidney injury (AKI), an elevated TyG index has demonstrated a robust correlation with the incidence of AKI. Nonetheless, the potential of the TyG index to predict AKI in critically ill patients with heart failure (HF) remains uncertain.

Methods
A cohort of participants was non-consecutively selected from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database and divided into quartiles based on their TyG index values. The incidence of AKI was the primary outcome. The secondary endpoint was in-hospital mortality within both the whole study population and the subset of AKI patients. The use of the renal replacement therapy (RRT) which represented the progression of AKI severity was also included as a secondary endpoint representing renal outcome. A restricted cubic splines model and Cox proportional hazards models were utilized to evaluate the association of TyG index with the risk of AKI in patients with HF in a critical condition. Kaplan-Meier survival analysis was employed to estimate primary and secondary endpoint disparities across groups differentiated by their TyG index.

Results
This study included a total of 1,393 patients, with 59% being male. The incidence of AKI was 82.8%. Cox proportional hazards analyses revealed a significant association between TyG index and the incidence of AKI in critically ill patients with HF. The restricted cubic splines model illustrated the linear relationship between higher TyG index and increased risk of AKI in this specific patient population. Furthermore, the Kaplan-Meier survival analyses unveiled statistically significant differences in the use of RRT across the subset of AKI patients based on the quartiles of the TyG index.

Conclusions
The results highlight the TyG index as a robust and independent predictor of the incidence of AKI and poor renal outcome in patients with HF in a critical condition. However, further confirmation of causality necessitates larger prospective studies.
Profiling ultra-processed foods in Thailand: sales trend, consumer expenditure and nutritional quality
Authors: Phulkerd Sirinya , Thongcharoenchupong Natjera , Dickie Sarah , Machado Priscila , Woods Julie , Mo-Suwan Ladda , Prasertsom Piyada , Ungchusak Chantana , Khitdee Chiraporn , Lawrence Mark 
Published: August 2023

Abstract
Background
Ultra-processed foods (UPF) are associated with adverse health outcomes. This study aimed to analyse the national trends in retail sales, consumer expenditure and nutritional quality of UPFs in Thailand.

Methods
The study used data from the Euromonitor Passport database for analysis of retail sales and consumer expenditure, and from the Mintel Global New Products Database for nutritional analysis using the WHO Southeast Asian Region nutrient profile model.

Results
The study found the highest per capita sales volume and value of UPFs in 2021 were sauces, dressings & condiments (8.4 kg/capita) and carbonated soft drinks (27.1 L/capita), respectively. However, functional & flavoured water, ready-made meals and baked goods had the highest observed (2012–2021) and expected (2021–2026) sales growth. Supermarkets were responsible for most of the UPF sales since 2012, but convenience stores had larger growth in retail values. Growth in consumer expenditure per capita on UPFs from 2012 to 2020, ranged between 12.7% and 34%, and till 2026 is forecast to grow between 26% and 30%. More than half of UPFs exceeded at least one nutrient cutoff, 59.3% for total fats, 24.8% for saturated fats, 68.2% for total sugars and 94.3% for sodium.

Conclusions
The findings suggest a need for regulatory and non-regulatory measures such as UPF taxation and marketing restrictions, and market incentives for producing non-UPFs. A system for regularly monitoring and evaluating healthiness (both nutritional and processing aspects) of food products, especially UPFs, is required.
Psychological interventions for individuals with Ehlers-Danlos syndrome and hypermobility spectrum disorder: a scoping review
Authors: Song Jessica Z. , Luong Dorothy , Feldman Estée C. H. , Tran Susan , Perrier Laure , Eubanks Kathleen , Bayley Mark , Kastner Monika , Slepian Maxwell , Munce Sarah E. P. 
Published: August 2023

Abstract
Purpose
To identify the nature and extent of the evidence on psychological interventions among individuals with Ehlers-Danlos Syndrome (EDS) and Hypermobility Spectrum Disorder (HSD).

Materials and methods
Eligible studies reported on psychological interventions for individuals of all ages with EDS and/or HSD. All studies published in English were included, with no restrictions to publication year or status. MEDLINE, CINAHL, EMBASE, and PsycINFO were searched. Two reviewers independently screened studies and abstracted data.

Results
This scoping review included 10 studies reporting on EDS, HSD, or both. Only cohort studies and case studies were identified. Four studies investigated Cognitive Behavioural Therapy (CBT), one investigated Dialectical Behavioural Therapy (DBT), two investigated psychoeducation, two investigated Intensive Interdisciplinary Pain Treatment (IIPT), and one investigated Acceptance Commitment Therapy (ACT). Interventions targeted pain management, self-destructive behaviours, and related psychological issues (e.g., depression/anxiety). Sample sizes were small (n < 50) for most studies and interventions were generally poorly described.

Conclusions
There is a critical need for high-quality research surrounding psychological interventions for individuals with EDS/HSD. Psychological interventions for these individuals are understudied and existing studies lack validity. Researchers should investigate psychological interventions for individuals with all types of EDS/HSD with high-quality studies to validate findings from the existing studies.
Disease risk estimates in V30M variant transthyretin amyloidosis (A-ATTRv) from Mallorca
Authors: Cisneros-Barroso E. , Gorram F. , Ribot-Sansó M. A. , Alarcon F. , Nuel G. , González-Moreno J. , Rodríguez A. , Hernandez-Rodriguez J. , Amengual-Cladera E. , Martínez-López I. , Ripoll-Vera T. , Losada-López I. , Heine-Suñer D. , Plante-Bordeneuve V. 
Published: August 2023

Abstract
Background
Variant transthyretin amyloidosis (A-ATTRv) is an autosomal dominant disease caused by a range of TTR gene variants which entail great phenotypical heterogeneity and penetrance. In Majorca, the A-ATTRv caused by the V30M gene variant (A-ATTRV30M) is the most common. Since asymptomatic carriers are at risk of developing the disease, estimating age of onset is vital for proper management and follow-up. Thus, the aim of this study was to estimate age-related penetrance in ATTRV30M variant carriers from Majorca.

Methods
The disease risk among carriers from ATTRV30M families from Majorca was estimated by Non-parametric survival estimation. Factors potentially involved in the disease expression, namely gender and parent of origin were also analysed.

Results
A total of 48 heterozygous ATTRV30M families (147 affected patients and 123 were asymptomatic carriers) were included in the analysis. Penetrance progressively increased from 6% at 30 years to 75% at 90 years of age. In contrast to other European populations, we observe a similar risk for both males and females, and no difference of risk according to the parent of origin.

Conclusions
In this first study assessing the age-related penetrance of ATTRV30M variant in Majorcan families, no effect of gender or parent of origin was observed. These findings will be helpful for improving management and follow-up of TTR variant carrier individuals.
Diversity and abundance of birds in dumpsites of Afar region, Ethiopia: implication for conservation
Authors: Tesfahunegny Weldemariam , Assefa Alembrhan 
Published: August 2023

Abstract
Background
Dumpsites play key role in conservation of birds. A study was conducted to assess the diversity and abundance of birds in dumpsites of Afar region, Ethiopia from August, 2019 to March, 2020, covering both the wet and dry seasons. A total of nine dumpsites that contain domestic wastes found in different towns of Afar region were selected. Point count technique was employed to identify and count the birds. Shannon-Weiner diversity index was used to estimate species diversity and Two-way ANOVA was used to test birds’ species richness and abundance variation across dumpsites and seasons.

Results
A total of 48 bird species consisting of one endemic and 10 globally threatened species were recorded. Red-billed Quelea, Marabou Stork and Egyptian Vulture were the most abundant species. There was a significant difference in bird species richness and abundance among dumpsites (F = 8.44, df = 8, P < 0.05) and F = 15.507, df = 8, P < 0.05), respectively. Moreover, a significant difference in abundance was also observed between the two seasons (F = 19.339, df = 1, P < 0.05). The highest species diversity (H’ = 3.18) was observed during wet season in Abala and Afambo dumpsites and the highest species evenness (E = 0.86) was observed during dry season in Afdera.

Conclusion
Bird species diversity and abundance among dumpsites was high, and man-made disturbance are main threats for conservation of birds in the area. Therefore, conservation measures are needed to maintain survival of birds mainly the globally threatened species. Moreover, proper management of dumpsites is vital to support the waste dependent birds.
Tunneling time and Faraday/Kerr effects in
systems
Authors: Gasparian Vladimir , Guo Peng , Pérez-Garrido Antonio , Jódar Esther 
Published: August 2023

Abstract
We review the generalization of tunneling time and anomalous behaviour of Faraday and Kerr rotation angles in parity and time

systems. Similarities of two phenomena are discussed, both exhibit a phase transition-like anomalous behaviour in a certain range of model parameters. Anomalous behaviour of tunneling time and Faraday/Kerr angles in

systems is caused by the motion of poles of scattering amplitudes in the energy/frequency complex plane.
Current clinicopathological characterisation of adamantinoma - a review of the literature
Authors: Węgrzyniak Agata , Wokurka Wojciech , Drobek Dominik , Winiarz Aleksandra , Szlendak Paula , Toś Katarzyna , Wojtala Kacper , Turek Michał , Wąsala Katarzyna , Grosman Sylwia 
Published: August 2023

Introduction and purpose
Adamantinoma is an exceedingly rare, primary bone tumour, that in most cases affects the diaphysis of the long bones, especially the tibia. Histologically it is epithelial cells clusters surrounded by spindle-cell osteofibrous components. Adamantinoma has metastatic potential to the lungs and local lymph nodes. Both the rarity of the disease and its nonspecific symptoms complicate diagnosis and treatment. Reviewing the up-to-date data regarding adamantinoma was the purpose of the work.
State of knowledge
During the 5th edition of the World Health Organization (WHO) classification of bone tumours in 2020 adamantionoma was classified in the newly established bone tumour class of the other mesenchymal tumours of bone. What is more its name was specified to adamantionoma of the long bone. According to literature and newest classification adamantinoma is divided into 3 types; the most common classic adamantinoma as well as less frequent OFD-like adamantinoma (osteofibrous like adamantinoma) and dedifferentiated adamantinoma. Diagnosis is challenging due to the rarity of occurrence, insufficient knowledge and misinterpretation of imaging studies resulting in the diagnosis of adamantinoma as other bone and soft tissue tumours.
Conclusions
Confirmation of the immunohistochemical profile, as well as the genetic profile of adamantionoma, which are increasingly well-defined, is essential for diagnosis. Imaging studies still remain the first method used in the diagnostic process. MRI appears to be the most suitable method for the imaging diagnosis of adamantinoma, due to excellent imaging of the tumour extent, including its surrounding soft tissue involvement and possible metastases. As far as treatment is concerned, there are still no precise guidelines and the best option remains tumour resection with large margins
Effects of Popping For Parkinson's dance class on the mood of people with Parkinson's disease
Authors: Sistarelli Simone , Annett Lucy E , Lovatt Peter J 
Published: August 2023

Background/Aims Depression, low mood and apathy can affect people with Parkinson's disease, impacting on their quality of life. The aim of this study was to investigate the effects of one Popping For Parkinson's dance session on the mood of people with Parkinson's disease. Methods A total of 33 people with Parkinson's disease, with a mean age of 67.5 years (standard deviation 10.3 years), mean Parkinson's level of 1.8 (standard deviation 1.6), took part in one Popping For Parkinson's dance class at four different locations: London (UK), Hatfield (UK), New York City (USA) and Turin (Italy). Participants' mood was measured with the Profile of Mood States questionnaire at four time points: immediately before the dance class, immediately after the dance class, 24hours after the dance class and 1 week after the dance class. Results Participants' total mood score and the subscale score of vigour increased, while the subscales of tension, depression, and confusion decreased on the Profile of Mood States, significantly immediately after the dance intervention. However, at 24 hours and 1week after the dance class, mood scores did not differ significantly compared with baseline measurements. The improvements in mood immediately after the dance class did not differ depending on sex, age, previous dance experience, the location of the dance class, stage of Parkinson's disease, presence of tremor and deep brain stimulation treatment. Conclusions Participating in a Popping For Parkinson's dance class boosts mood in the short term, and this improvement lasts less than 24hours. This finding has implications for the provision of dance classes, suggesting that regular attendance may be necessary for sustained improvements. Further studies are needed to determine whether attending a series of Popping for Parkinson's classes may have longer-term effects.
Capturing the perspectives on treatment of chronic non-cancer pain using non-pharmacological approaches
Authors: Westrap Sarah 
Published: August 2023

Opioid therapy was standard treatment for all types of pain, until the opioid epidemic in the US. Research has since uncovered a lack of efficacy for treating chronic non-cancer pain with opioids and the detrimental effects they may cause. By Sarah Westrap Background Opioid therapy was the mainstay of treatment for all types of pain, until the opioid epidemic of the 1980's – 2000's. Research has since uncovered a lack of efficacy for treating chronic non-cancer pain with opioids and the detrimental effects they may cause. Aim To uncover a range of perspectives which encompass the complexities of care of the patient with CNCP. Methods A critical review of the literature using qualitative study designs. Databases searched include Cumulative Index to Nursing and Allied Health (CINAHL), British Nursing Index (BNI), Pubmed, Embase and PsychINFO. PICO search terms were used, and Boolean operators were applied. Research studies selected for inclusion were put through McMaster critical review forms and findings placed in a theme matrix. Findings There were 3 main themes that were drawn out from the research papers critiqued. These relate firstly to the patients perspective of living with chronic pain non-cancer pain. Patients seek adequate pain relief but have misgivings around the adverse effects of opioids, welcoming non-pharmacological approaches such as acupuncture and chiropractic treatment but patients view may be sceptic. Secondly the relationship between the patients and healthcare professional (HCP) can include clues during communication which may led to change in treatment. Lastly the views of HCP's who often cite lack of training in managing patients with chronic non-cancer pain and fear of difficult interactions regarding opioid use. Conclusion Individuals have unique characteristics; treatment models can be applied such as an integrated medical group visit (IMGV) or Horne model to connect HCP and patient, offering solutions in reducing or stopping opioid therapy.
An introduction to forest bathing for practice nurses
Authors: Henry Heather 
Published: August 2023

Heather Henry explains the concept of ‘forest bathing’ or ‘immersion in nature’ which can be incorporated into general practice nursing as a low cost social prescribing solution Forest bathing or Shinrin-yoku is a form of ecotherapy or green therapy that may be described as an ‘immersion in nature’. It was introduced by the Japanese government in the 1980's and has undergone extensive research to understand how it supports wellbeing. Since forest bathing is a no-cost way to help people with long term conditions, this article outlines the basic concept and how it can be incorporated into general practice nursing as a social prescribing solution. Some simple forest bathing invitations are offered, based on the author's practical experience.
Factors associated with oral health care behaviors of pregnant women in a northeastern province in Thailand: A hospital-based cross-sectional study
Authors: Bunnatee Pimchanok , Abdulsalam Fatima Ibrahim , Phoosuwan Nitikorn 
Published: August 2023

Background
Oral healthcare behavior leads to oral health status. Factors associated with oral healthcare behavior might affect oral hygiene in pregnant women, who are at high risk for gingivitis and dental caries. This study aimed to explore factors associated with oral healthcare behaviors during pregnancy among pregnant women in a northeastern province of Thailand.

Method
A total of 405 pregnant women who attended antenatal care clinics at one of the government hospitals in the province were invited to participate in this cross-sectional study. Dentists in the hospitals measured pregnant women’s gingivitis and dental calculus status using mouth mirrors and explorers. A structured questionnaire was used to obtain variables of interest. Linear regression analysis, Beta and 95% confidence interval (CI) were applied.

Results
The majority were 20–24 years old (33.6%). Most of the participants had received upper secondary education (37.6%). Majority had gingivitis (88.1%) and dental calculus (88.6%). The findings revealed that age (Beta = -0.129, 95%CI = -0.269, -0.016), educational level (Beta = 0.118, 95% CI = 0.110, 0.183), and oral health literacy (Beta = 0.283, 95% CI = 0.156, 0.319) were statistically significant factors associated with oral healthcare behaviors.

Conclusion
Younger pregnant women had better oral healthcare behaviors than older pregnant women and pregnant women had better oral healthcare behaviors due to higher educational levels and oral health literacy. Oral health promotion should be improved through oral health literacy, and interventions should be added to improve oral care skills particularly in older pregnant women as they are at a greater risk for poor oral healthcare behaviors.
The effect of tranexamic acid on intraoperative blood loss in patients undergoing brain meningioma resections: Study protocol for a randomized controlled trial
Authors: Yu Haojie , Liu Minying , Zhang Xingyue , Ma Tingting , Yang Jingchao , Wu Yaru , Wang Jie , Li Muhan , Wang Juan , Zeng Min , Zhang Liyong , Jin Hailong , Liu Xiaoyuan , Li Shu , Peng Yuming 
Published: August 2023

Introduction
Tranexamic acid (TXA) has been proven to prevent thrombolysis and reduce bleeding and blood transfusion requirements in various surgical settings. However, the optimal dose of TXA that effectively reduce intraoperative bleeding and blood product infusion in patients undergoing neurosurgical resection of meningioma with a diameter ≥ 5 cm remains unclear.

Methods
This is a single-center, randomized, double-blinded, paralleled-group controlled trial. Patients scheduled to receive elective tumor resection with meningioma diameter ≥ 5 cm will be randomly assigned the high-dose TXA group, the low-dose group, and the placebo. Patients in the high-dose TXA group will be administered with a loading dose of 20 mg/kg TXA followed by continuous infusion TXA at a rate of 5 mg/kg/h. In the low-dose group, patients will receive the same loading dose of TXA followed by a continuous infusion of normal saline. In the control group, patients will receive an identical volume of normal saline. The primary outcome is the estimated intraoperative blood loss calculated using the following formula: collected blood volume in the suction canister (mL)–the volume of flushing (mL) + the volume from the gauze tampon (mL). Secondary outcomes include calculated intraoperative blood loss, intraoperative coagulation function assessed using thromboelastogram (TEG), intraoperative cell salvage use, blood product infusion, and other safety outcomes.

Discussion
Preclinical studies suggest that TXA could reduce intraoperative blood loss, yet the optimal dose was controversial. This study is one of the early studies to evaluate the impact of intraoperative different doses infusion of TXA on reducing blood loss in neurological meningioma patients.

Trial registration
ClinicalTrials.gov, NCT05230381. Registered on February 8, 2022.