bluuebunny/crossref_metadata_2025_split huggingface dataset:
Harmony or Cacophony? A Disaggregated Analysis of Aid Fragmentation
Authors: Carlitz Ruth D. , Ziaja Sebastian 
Published: April 2023

AbstractAid effectiveness is widely understood to suffer when multiple donors operate in the same space, but recent studies indicate benefits of fragmentation. We posit that these mixed findings may reflect differences across aid sectors — and also show how the level of implementation can condition the interpretation of results. Cross-national time-series analysis of 152 countries implies aid fragmentation can promote child survival and improve governance. However, analysis of subnational variation in Sierra Leone and Nigeria suggests the presence of more donors is associated with worse health outcomes, but better governance outcomes. Having more donors in a locality may thus be beneficial when they are working to improve the systems through which policies are implemented, but harmful if they target policy outcomes directly. A survey of Nigerian civil servants suggests potential mechanisms: fragmentation in health aid may lead to internal “brain drain” and pressure to alter projects, whereas diversity in governance aid might promote meritocratic behavior.
The influence of sociodemographic variables and traumatic life events on the alcohol consumption of homeless people in Spain
Authors: Fajardo-Bullon Fernando , Esnaola Igor , Hermans Koen , Anderson Isobel 
Published: April 2023

AbstractThis article uses the latest Spanish Survey on Homeless People to address whether traumatic experiences, sociodemographic characteristics, and homeless categories are associated with being an abstainer, a risky drinker, or a high-risk drinker. The sample was composed of 3,407 Spanish homeless adults ranging from 18 to 93 years old (Mage = 41.30, SD = 13.86). A multinomial logistic regression model was used. Results showed that experiencing childhood problems and demographic factors, such as being male, single, over 50, living in insecure or inadequate housing, and having lived in a shelter for less than three months were associated with alcohol consumption. Likewise, traumatic life events, such as a parent having been in prison, illness, disabilities, and alcohol problems in the family or themselves, are also risk factors in alcohol use. The findings from Spain support that early intervention strategies both disrupt cumulative inequality and empower those at risk of homelessness to develop their skills and improve their wellbeing.
SbtB — der fehlende Sensor für anorganischen Kohlenstoff in Cyanobakterien
Authors: Selim Khaled A. , Zimmer Erik 
Published: April 2023

AbstractPII superfamily consists of signal transduction proteins found in all domains of life. PII-like proteins evolved to fulfill diverse, yet poorly understood cellular functions. We recently identified the PII-like protein SbtB in cyanobacteria as a sensor of various adenine nucleotides including the second messengers cAMP and c-di-AMP. This highlights SbtB as a central switch-point in cyanobacterial physiology, integrating not only signals from the energy state and carbon supply, but also signals from the day/night status, to regulate the glycogen metabolism.
Strukturierte RNAs in Viren
Authors: Ochsenreiter Roman , Wolfinger Michael T. 
Published: April 2023

AbstractEvolutionarily conserved RNAs in untranslated regions are key regulators of the viral life cycle. Exoribonuclease-resistant RNAs (xrRNAs) are particularly interesting examples of structurally conserved elements because they actively dysregulate the messenger RNA (mRNA) degradation machinery of host cells, thereby mediating viral pathogenicity. We review the principles of RNA structure conservation in viruses and discuss potential applications of xrRNAs in synthetic biology and future mRNA vaccines.
Developments in Fungal Serology
Authors: White P. Lewis 
Published: April 2023

Abstract
Purpose of Review
The true incidence of fungal disease is hampered by conventionally poor diagnostic tests, limited access to advanced diagnostics, and limited surveillance. The availability of serological testing has been available for over two decades and generally underpins the modern diagnosis of the most common forms of fungal disease. This review will focus on technical developments of serological tests for the diagnosis of fungal disease, describing advances in clinical performance when available.

Recent Findings
Despite their longevity, technical, clinical, and performance limitations remain, and tests specific for fungal pathogens outside the main pathogens are lacking. The availability of LFA and automated systems, capable of running multiple different tests, represents significant developments, but clinical performance data is variable and limited.

Summary
Fungal serology has significantly advanced the diagnosis of the main fungal infections, with LFA availability increasing accessibility to testing. Combination testing has the potential to overcome performance limitations.
The Musical Turn in Biosemiotics
Authors: Slayton Matthew A , Hendlin Yogi Hale 
Published: April 2023

AbstractHuman music and language are two systems of communication and expression that, while historically considered to overlap, have become increasingly divergent in their approach and study. Music and language almost certainly co-evolved and emerged from the same semiotic field, and this relationship as well as co-origin are actively researched and debated. For the sake of evaluating the semiotic content of zoomusicology, we investigate music from a ‘bottom-up’ biosemiotic functionalist account considering iconic, indexical, and symbolic forms of meaning not in a hierarchy but according to their effects on agents. Such an approach avoids overintellectualizing the representational aspects of music, and instead inverts, as it were, the traditional hierarchy of semiotic categories to produce illocutionary effects. Understanding aesthetics and action not as a priori separate but rather fundamentally co-arising elements of the same events. The focus of musicality again returns to interpretation and how semiosis precipitates expression.
The Uncanny Effect of Speech: The Impact of Appearance and Speaking on Impression Formation in Human–Robot Interactions
Authors: Gurung Neelu , Grant Janie Busby , Hearth Damith 
Published: April 2023

Abstract
This study explores the impact of appearance and speech on human perceptions of faces in human- robot interactions. Three videos were generated depicting the real face of an artist and two virtual versions of the same artist, with increasing resolution and fidelity. Each video was presented with and without speech, with matching levels of fidelity to the faces (real human speech and machine- generated speech of two levels of realism). Participants viewed all six videos and rated them on measures such as convincing, trustworthy, realistic, likable, showed biological movement, reassuring, friendly, familiar, and humanness. We found that the inclusion of speech (real) had a significant positive impact on the impression formation of real human appearance. In contrast, perceptions of the virtual avatars were more negative when speech (machine-like) was incorporated. This study illustrates the differential effects that speech can have on virtual faces in interactive settings.
Coexistence of a novel SETD2-ALK, EML4-ALK double-fusion in an advanced lung adenocarcinoma patient after alectinib resistant and response to immunotherapy combined with chemotherapy: a case report
Authors: Zhu Lin , Qin Jing 
Published: April 2023

AbstractThe single echinoderm microtubule-associated protein-like 4 (EML4) gene and anaplastic lymphoma kinase (ALK) gene fusion is the most common variant of ALK rearrangements in non-small cell lung cancer (NSCLC). Herein, we firstly report that coexistence of a novel histone methyltransferase (SETD2)-ALK, EML4-ALK double-fusion is sensitive to alectinib as first-line therapy, and response to immunotherapy combined with chemotherapy after resistant. The patient responded to alectinib as a first-line therapy and achieved progression-free survival (PFS) for 26 months. After resistance, liquid biopsy showed that the reason of drug resistance was the disappearance of SETD2-ALK and EML4-ALK fusion variants. In addition, chemotherapy combined with immunotherapy subsequently achieved a survival benefit of more than 25 months. Therefore, alectinib may be a viable therapeutic option for NSCLC patients with double ALK fusion and immunotherapy combined with chemotherapy may be a viable therapeutic option when double ALK fusion loss may be the mechanism of alectinib resistance.
Acoustic preliminary design of a low-noise fan stage considering a variable-area nozzle and variable-pitch rotor blades
Authors: Moreau A. , Schnell R. , Mennicken M. 
Published: April 2023

AbstractA low-noise low-pressure ultra-high-bypass-ratio fan stage to be implemented in the next generation of aircraft engines is described and evaluated acoustically with semi-empirical and analytical methods suited for preliminary design. As expected, good reduction potentials are observed for the jet noise and fan tonal noise components when the UHBR design is compared to current fans in service. However, concerns are identified for fan broadband noise, which are attributed to the off-design operation of the UHBR fan too close from its stability limit. By unloading the fan and thus reducing the size of the rotor wakes, the variable-area nozzle provides a substantial fan broadband noise reduction with a nozzle opened by around 15% from its design value. Alternatively, with the variable-pitch fan, closing the rotor blades by roughly 5° turns out to be an even more effective method to reduce fan noise, as the unloading mechanism is combined with a stronger tilting of the rotor wakes and a lower intra-stage flow Mach number. Opening the nozzle or closing the blades beyond the setting that provides the best fan efficiency is not recommended as the acoustic benefit progressively vanishes, whereas technical feasibility becomes more challenging. Finally, the presence of one of these systems may allow for the design of a low-solidity rotor, with a smaller contribution from the rotor wakes and thus a weaker fan noise emission.
Against the grain: environmental laws, local botanical knowledge, and housing access in Rio de Janeiro
Authors: Lesser Chris N. , Brandes Arno F. N. 
Published: April 2023

AbstractThis article considers how the construction practices of marginalized communities in Rio de Janeiro link the provision of essential housing to distant forest environments and markets for wood building materials. As elsewhere in Brazil, many families without access to real estate markets have built their own homes using locally available materials, a right protected by the 1988 Constitution and federal law. Today, these houses are typically built from reinforced concrete and clay bricks and finished with a roof of clay tile or cheaper fiber-cement corrugate. Production and sale of fiber-cement, which contains asbestos, were restricted by Rio de Janeiro State law in 2001 and ruled unconstitutional by Brazil’s Supreme Court in 2017. But little attention has been given to the human and environmental health effects of other building materials. This article examines the timber frame to which roof tiles are affixed. Maçaranduba is the main wood used in roof construction and is the most traded wood in Brazil, with production practices linked to environmental and social violence. Brazil’s laws presently subsidize plantation-grown pine and eucalyptus as “sustainable” alternatives to native hardwoods. The chemical treatments commonly applied to render these woods resistant to decay, however, contain potent environmental toxins. Moreover, the degree to which builders of essential housing actually use these products is unstudied. We argue that legislation has moved “against the grain” or without close attention to the botanical knowledge expressed in vernacular architectures and the needs of marginalized socio-ecologies intimately linked through the production of essential housing.
A Globally Applicable Method for NDVI Estimation from Sentinel-1 SAR Backscatter Using a Deep Neural Network and the SEN12TP Dataset
Authors: Roßberg Thomas , Schmitt Michael 
Published: April 2023

AbstractVegetation monitoring is important for many applications, e.g., agriculture, food security, or forestry. Optical data from space-borne sensors and spectral indices derived from their data like the normalised difference vegetation index (NDVI) are frequently used in this context because of their simple derivation and interpretation. However, optical sensors have one major drawback: cloud coverage hinders data acquisition, which is especially troublesome for moderate and tropical regions. One solution to this problem is the use of cloud-penetrating synthetic aperture radar (SAR) sensors. Yet, with very different image characteristics of optical and SAR data, an optical sensor cannot be easily replaced by SAR sensors. This paper presents a globally applicable model for the estimation of NDVI values from Sentinel-1 C-band SAR backscatter data. First, the newly created dataset SEN12TP consisting of Sentinel-1 and -2 images is introduced. Its main features are the sophisticated global sampling strategy and that the images of the two sensors are time-paired. Using this dataset, a deep learning model is trained to regress SAR backscatter data to NDVI values. The benefit of auxiliary input information, e.g., digital elevation models, or land-cover maps is evaluated experimentally. After selection of the best model configuration, another experimental evaluation on a carefully selected hold-out test set confirms that high performance, low error, and good level of spatial detail are achieved. Finally, the potential of our approach to create dense NDVI time series of frequently clouded areas is shown. One limit of our approach is the neglect of the temporal characteristics of the SAR and NDVI data, since only data from a single date are used for prediction.
Quality assessment of higher resolution images and videos with remote testing
Authors: Göring Steve , Rao Rakesh Rao Ramachandra , Raake Alexander 
Published: April 2023

AbstractIn many research fields, human-annotated data plays an important role as it is used to accomplish a multitude of tasks. One such example is in the field of multimedia quality assessment where subjective annotations can be used to train or evaluate quality prediction models. Lab-based tests could be one approach to get such quality annotations. They are usually performed in well-defined and controlled environments to ensure high reliability. However, this high reliability comes at a cost of higher time consumption and costs incurred. To mitigate this, crowd or online tests could be used. Usually, online tests cover a wider range of end devices, environmental conditions, or participants, which may have an impact on the ratings. To verify whether such online tests can be used for visual quality assessment, we designed three online tests. These online tests are based on previously conducted lab tests as this enables comparison of the results of both test paradigms. Our focus is on the quality assessment of high-resolution images and videos. The online tests use AVrate Voyager, which is a publicly accessible framework for online tests. To transform the lab tests into online tests, dedicated adaptations in the test methodologies are required. The considered modifications are, for example, a patch-based or centre cropping of the images and videos, or a randomly sub-sampling of the to-be-rated stimuli. Based on the analysis of the test results in terms of correlation and SOS analysis it is shown that online tests can be used as a reliable replacement for lab tests albeit with some limitations. These limitations relate to, e.g., lack of appropriate display devices, limitation of web technologies, and modern browsers considering support for different video codecs and formats.
Bioelectrical impedance analysis in the BaSAlt cohort-study: the phase angle as an additional parameter for sarcopenia quantification among German nursing home residents?
Authors: Haigis Daniel , Wagner Silas , Thiel Ansgar , Nieß Andreas M. ,   the BaSAlt study team
Published: April 2023

Abstract
Purpose
Sarcopenia is characterized by the loss of muscle mass, strength, and physical functioning. The bioelectrical impedance analysis (BIA) is a simplify method for the measurement of muscle quantity and quality. But there is a lack of evidence in the interpretation of the muscle quality parameter phase angle (PhA), which was recommended by the European Working Group on Sarcopenia in Older People 2 (EWGSOP2). We hypothesize that the PhA shows differences between sarcopenia categorized groups and can be used as an additional parameter for sarcopenia quantification among residents of nursing homes (NH).

Methods
Based on EWGSOP2 specifications, 78 residents from five German NH was categorized into sarcopenia groups. Group comparisons with Kruskal–Wallis tests, Dunn–Bonferroni post-hoc-Tests, and correlations with Spearman coefficients were conducted with the muscle quality parameter PhA.

Results
Significant group differences by Kruskal–Wallis test for PhA was detected (H = 8.150, p = 0.017). The Dunn–Bonferroni post-hoc-Test showed significant results by group comparison for “confirmed/ severe sarcopenia” (4.1° [3.1–5.0]) with “no sarcopenia” (4.6° [3.7–11.2]; p =0 .049) and “probable sarcopenia” (4.7° [3.4–13.5]; p = 0.016), respectively.

Conclusions
There is a limitation for differentiation in preliminary stage of sarcopenia among multimorbid NH residents by PhA. Moreover, further research for specific cut-off-values and the individual sarcopenia progression monitoring by PhA are needed.

Trial registration
No. AZ A2.5.4-096_aa (Date of approval: July 2019).
Adoption of online mathematics learning in Ugandan government universities during the COVID-19 pandemic: pre-service teachers’ behavioural intention and challenges
Authors: Kansiime Geofrey , Batiibwe Marjorie Sarah Kabuye 
Published: April 2023

AbstractIn the wake of COVID-19, higher education institutions worldwide were forced to continue teaching and learning through online means. However, it was only during the pandemic that institutions in Uganda, such as Kabale University, embraced online learning. Against this background, one could not predict how students drastically adapted to the new normal, especially in mathematics, which requires a lot of practice. Thus, this study sought to establish the relationship between behavioural intention to use technology and the adoption of online mathematics learning among pre-service teachers at Kabale University. We conceptualized behavioural intention to use technology according to the Unified Theory of Acceptance and Use of Technology (UTAUT) as comprising four factors: performance expectancy, effort expectancy, facilitating conditions, and social influence. This mixed methods study followed a cross-sectional correlational survey and hermeneutic phenomenological research designs. We collected data from 140 pre-service mathematics teachers, who were sampled using stratified and simple random sampling techniques, through a self-administered questionnaire. Also, we collected qualitative data through nine face-to-face interviews of pre-service mathematics teachers using criterion sampling, where the most prominent criterion was the participant's experience with the phenomenon under study. Using Pearson’s linear correlation, results showed that all UTAUT constructs were related to the adoption of online learning. Simple linear regression revealed that facilitating conditions were the strongest predictor. Furthermore, the narrative analysis indicated that, among others, a lack of technological knowledge hindered learners’ effective participation in online mathematics lectures. Therefore they barely benefited from online learning. Thus, we recommend government universities enhance teachers’ and learners’ technological knowledge, among other facilitating conditions such as establishing strong on-campus Wi-Fi connections as online learning continues.
Circulating Political Information in Colombia: Written and Oral Communication Practices in the Second Half of the Nineteenth Century
Authors: Galán-Guerrero Luis Gabriel 
Published: April 2023

AbstractThis article examines how people gathered and transmitted political information in Colombia during the second half of the nineteenth century. Existing scholarship has predominantly focused on the study of the press in Colombia and Latin America. However, few historians have explored other forms of information, such as telegrams, rumours and letters, or how Colombians combined these. By focusing on how various forms of information circulated through political, familial and commercial networks, this study offers a new dimension to our understanding of communications in Colombia. It argues that this was a period of increasing circulation of information due to social, political and economic change, as well as new links between oral and written practices. Thus, this article illuminates how Colombians circulated political information in a society of restricted literacy in post-colonial Latin America, offering new insights into politics, communications and the interplay between written and oral culture.
Psychometric properties of the PG-13-R scale to assess prolonged grief disorder among bereaved Iranian adults
Authors: Ashouri Ahmad , Yousefi Shahab , Prigerson Holly G. 
Published: April 2023

AbstractObjectivesThe PG‐13‐Revised (PG-13-R) is a self-report measure to assess prolonged grief disorder (PGD) in terms of Diagnostic and Statistical Manual of Mental Disorders, fifth revision, Text Revision. This measure has been shown to yield good psychometric properties in Western samples. This study aimed to evaluate the psychometric properties of the Persian PG-13-R.MethodsThree hundred forty-seven individuals (209 women and 138 men) fully completed the scales. The participants were recruited using convenience sampling. The confirmatory factor analysis (CFA), convergent and divergent validity, and reliability of the Persian version of the PG-13-R were evaluated.ResultsCFA results of a unidimensional model support the construct validity of this version of the PG-13-R. The results of this study demonstrated that this version of the PG-13-R has internal consistency reliability (omega coefficient of 0.93), and the test–retest reliability with an interval of 6 weeks was 0.89. The convergent and divergent validity was shown with significant correlations between the PG-13-R and measures of depression, PTSD, functional impairment, and hope.Significance of resultsOverall, the Persian version of the PG-13-R showed good psychometric properties in the Iranian population.