bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modified Activated carbon by in-situ co-precipitation process of tetra metal oxide magnetic nanocomposite for adsorption of Th(IV) from aqueous media
Authors: Elhefnawy Olivea A. , Elabd Amira A. 
Published: April 2023

Abstract

Activated carbon was doped by tetra metal oxide magnetic nanoparticles (Fe3n Con Cun Srn O7n) by in-situ co-precipitation process to prepare a new efficient adsorbent (AC4MO) for thorium ions removal from aqueous media. Also, tetra metal oxide magnetic nanoparticles (4MO) used for removing thorium ions from aqueous media. The morphology and structural properties of the new magnetic nanocomposites 4MO and AC4MO have been described by SEM, EDX, TEM, XRD, and FTIR. Four operating conditions parameters have been studied in the adsorption process for new adsorbents, pH, contact time, initial concentration, and temperature. The adsorption kinetics has been well described by the pseudo-second order model, while the Langmuir model better fits the adsorption isotherms. 4MO and AC4MO adsorption capacities were 222.22 and 714.29 mg/g, respectively. Thermodynamic parameters have been calculated to indicate the spontaneous and endothermic nature of the adsorption process and show that AC4MO has little sensitivity to temperature. The results showed that 4MO and AC4MO have higher selectivity towards Th(IV) ions from radioactive wastewater. AC4MO is the more effective adsorbent and has a higher adsorption capacity for Th(IV) as discussed in the comparative study.
The category of noncrossing partitions
Authors: Igusa Kiyoshi 
Published: April 2023

Abstract
In [18], we introduced “picture groups” and computed the cohomology of the picture group of type An. This is the same group what was introduced by Loday [21] where he called it the “Stasheff group”. In this paper, we give an elementary combinatorial interpretation of the category associated to An by the general construction given in [14] and prove that the classifying space of this category is locally CAT(0) and thus a K(π,1). We prove a more general statement that classifying spaces of certain “cubical categories” are locally CAT(0). The objects of our category are the classical noncrossing partitions introduced by Kreweras [20]. The morphisms are binary forests. This paper is independent of [14] and [18] except in the last section where we use [14] to compare our category with the category with the same name given by Hubery and Krause [9].
2010 Mathematics Subject Classification. 16G20; 20F55.
Inverse Design of Enzymatic Reaction Network States
Authors: Sluijs Bob van , Zhou Tao , Helwig Britta , Baltussen Mathieu , Nelissen Frank , Heus Hans , Huck Wilhelm 
Published: April 2023

Abstract
Kinetic modelling of in vitro constructed enzymatic reaction works is vital to understand and control the complex behaviours emerging from the abundant nonlinear interactions inside. However, modelling is severely hampered by the lack of training data. Here, we introduce a methodology that combines an active learning-like approach and flow chemistry to efficiently create optimized datasets for a highly interconnected enzymatic reactions network with multiple inputs and multiple outputs. The optimal experimental design (OED) algorithm designed a sequence of out-of-equilibrium perturbations to maximise the information about the reaction kinetics, yielding a descriptive model that allowed inverse design of the output of the network towards any cost function. We experimentally validated the model by forcing the network to produce different product ratios while maintaining a minimum level of overall conversion efficiency. Our workflow scales with the complexity of the system and enables the inverse design of previously unobtainable network outputs.
Optimal operation of hydropower systems with environmental constraints on reservoir management
Authors: Schäffer Linn Emelie , Bakken Tor Haakon , Helseth Arild , Korpås Magnus 
Published: April 2023

Abstract

Hydropower systems' unique capability to provide flexibility and long-term energy storage makes the low-carbon technology a key contributor to cost-effective and reliable decarbonisation of power systems. To ensure sustainable operation, environmental regulations are normally imposed on the plants. Some of these regulations can be difficult to model in existing scheduling tools based on optimisation because of their non-convex and logical characteristics. This study assesses the operational impacts of two types of environmental reservoir constraints, as well as the economic impacts of considering these constraints in medium-term hydropower scheduling. The results show that optimal reservoir management may change considerably due to these types of constraints. Furthermore, improved planning results in a decent increase in expected profit to the power producer under certain price assumptions in several of the simulated cases.
Effect of adalimumab on choroidal thickness and choroidal vascularity index in eyes with non-infectious uveitis using enhanced-depth imaging optical coherence tomography
Authors: Evereklioglu Cem , Arslantas Elif Er , Sener Hidayet , Akkul Zeynep , Gahramanov Kamran , Sevim Duygu Gulmez , POLAT Osman Ahmet , Horozoglu Fatih 
Published: April 2023

Abstract
Objective
To evaluate the effect of adalimumab (ADA) on choroidal thickness (ChT) and choroidal vascularity index (CVI) in eyes with non-infectious uveitis (NIU).
Methods
Thirty-seven eyes with NIU, 38 eyes of non-uveitic (NU) patients, and 40 control eyes were included. ADA was used for anti-TNF-naive adult (80mg) or pediatric (40mg) patients with refractory NIU, then 40mg every 2-week (20mg in children < 30kg) with controls at weeks 1, 4, 12, and 24. Images were used to measure central, nasal, and temporal ChT, and the luminal area (LA), stromal area (SA), and total choroidal area (TCA) were analysed using enhanced-depth imaging optical coherence tomography (EDI-OCT) by ImageJ software. The CVI was then calculated as the ratio of LA to TCA.
Results
Mean ages were similar between the groups. Mean (SE) subfoveal ChT measurements for each location were also similar (for each, p > 0.05). However, calculated CVI values in eyes with NIU (0.63 ± 0.007) were significantly (p < 0.001) lower than NU eyes (0.66 ± 0.006) and controls (0.70 ± 0.007) (p < 0.001). Moreover, CVI was significantly lower in NU eyes compared to controls (p < 0.001). There were no significant CVI changes between the consecutive visits after ADA therapy in eyes with NIU (for each, p > 0.05).
Conclusions
Decreased CVI in NIU and NU eyes indicates that systemic inflammation affects the choroidal vasculature and perfusion both in the presence and absence of ocular involvement. Although CVI may be used as a possible novel tool in monitoring ocular involvement and progression of NIU, CVI does not seem to be a biomarker for treatment monitoring in NIU.
Incidence and Spatial Distribution of Bacterial Meningitis, Uganda, 2015-2018
Authors: Gonahasa Doreen N. , Kyamwine Irene B. , Kwesiga Benon , Bulage Lilian , Ario Alex R. 
Published: April 2023

Abstract
Background: Uganda is one of the countries with the highest risk of meningitis because it lies within the extended meningitis belt of Sub-Saharan Africa. The most susceptible regions include West Nile, Bunyoro, Acholi, Lango, Teso, and Karamoja regions. Although there have been efforts to vaccinate against meningitis, sporadic cases still occur. Weestimated the incidence and described the spatial distribution of bacterial meningitis in Uganda using surveillance data, 2015-2018, to inform targeted interventions.
Methods: We analysed bacterial meningitis surveillance data from the District Health Information System 2. We specifically considered data on suspected bacterial meningitis cases. We calculated the overall meningitis incidence during 2015-2018 and disaggregated the incidence by age-group, sex, and region. We generated choropleth maps to describe the meningitis incidence per year at the regional level.
Results: The overall meningitis incidence was4.7/100,000. Overall, there was an increase in the incidence of meningitis from 3.2/100,000 in 2015 to 5.3/100,000 population in 2017; and a decline in 2018. The incidence was higher among under-five population ranging between 6.5-10.6/ 100,000 compared to those aged five and above (2.5-4.2/ 100,000). Karamoja region was most affected compared to the other 14 regions in the country.
Conclusion: Overall, there was an increase in the incidence of meningitis from 2015 to 2017; and a decline in 2018 after a countrywide mass vaccination campaign in 2017. Children under five and Karamoja region were most affected. Regardless of efforts to vaccinate, meningitis remains a disease of public health concern. We recommended that Ministry of Health should introduce the meningitis vaccine in routine immunisation.
Analysis of key factors of gas content in fold area based on grey entropy correlation theory
Authors: Jiao Huice , Song Weihua 
Published: April 2023

Abstract
The gas storage conditions in a fold area are complex, and there are many influencing factors. Therefore, it has been the focus and challenge of regional gas control. Based on the analysis of the forces acting on the geological structure in a fold area and the law of gas migration, this study derives six factors controlling the gas content in the fold area. Then combined with grey entropy correlation theory, a grey entropy correlation analysis method is proposed to screen the key factors of gas occurrence in complex fold area. Finally, taking the anticline fold area of a mine in western China as an example, the main factors controlling the gas content in this area are studied using the grey entropy relational analysis method. And the fitting equations of the regional gas content and main controlling factors are obtained using the multiple regression method. This study provides a basis for mine gas disaster prevention and control. These results show that the entropy degree of the burial depth of the coal and the distance between the measuring point and the outcrop of the coal seam are 0.996 and 0.989, respectively, which are the key factors controlling the gas occurrence in this area. Then we use multiple regression method to get the regression equation of regional gas content and main control factors, which provides a basis for mine gas disaster prevention and control.
CO2 adsorption on carbonaceous materials obtained from forestry and urban waste materials: A comparative study.
Authors: Garces-Polo Siby Inés , Polo Siby I. Garcés - , Vargas Gabriel de Jesús Camargo , Estupiñán Paola Rodríguez , Hernández-Barreto Diego Felipe , Giraldo Liliana , Piraján Juan Carlos Moreno - 
Published: April 2023

Abstract

The increasing emissions of gaseous pollutants of anthropogenic origin, such as carbon dioxide (CO2), which causes global warming, have promoted a great interest in developing and improving processes that allow their mitigation. Among them, adsorption on porous materials has been proposed as a sustainable alternative. This work presents a study of CO2 equilibrium adsorption at low temperatures, (0, 10, and 20°C) over a wide range of low pressures, on activated carbon derived from eucalyptus (ES) and patula pine (PP) forest waste and carbonaceous material derived from waste tires (WT). Previously the precursors of these materials were prepared and characterized in terms of their physicochemical properties and thermochemically treated with phosphoric acid (ES and PP) and oxidized with nitric acid (in the case of WT). Additionally, these materials were used to obtain monoliths using uniaxial compaction techniques and different binding agents, obtaining better results with montmorillonite. All six adsorbent solids were characterized through their textural and chemical properties and proven in CO2 adsorption. The highest specific surface area (1405 m2/g), and micropore properties were found for activated carbon derived from eucalyptus allowing the highest adsorption capacity ranging from 2.27 mmol/g (at 0°C and 100 kPa) to 1.60 mmol/g (at 20°C and 100 kPa). The activated carbon monoliths presented the lowest CO2 adsorption capacities, however, the materials studied showed a high potential to be focused on CO2 capture and storage applications at high pressures. The isosteric heats of adsorption were also estimated for all the materials and results ranged from 16 to 45 kJ/mol at very low coverage explained in terms of the energetic heterogeneity and weakly repulsive interactions between adsorbed CO2 molecules.
Pharmaceutical care of patients with nasopharyngeal carcinoma complicated with lung abscess by clinical pharmacists
Authors: Li Qinchuan , Zou Ya , Yang Yali , Guan Wenju 
Published: April 2023

Abstract
A patient with nasopharyngeal carcinoma complicated with lung abscess was given full pharmaceutical care by clinical pharmacists, especially for the treatment of antitumor drugs (chemotherapy, nituzumab, radiotherapy) and lung abscess. To explore the significance of pharmaceutical care for pulmonary abscess in patients with nasopharyngeal carcinoma during antitumor therapy. Finally, the antitumor treatment effect of the patient reached PR, the adverse reactions were improved, the lung abscess lesions were effectively improved, and the individualized medication monitoring by clinical pharmacists achieved phased results. Conclusion This case is the first reported case of nasopharyngeal carcinoma complicated with lung abscess and clinical pharmacists are involved in the treatment. It is of great significance for the selection of antitumor treatment plan, the selection of antibacterial drug varieties and the treatment course of similar patients complicated with lung abscess during antitumor therapy.
Music Recommendation Algorithms Based On Knowledge Graph and Multi-task Feature Learning
Authors: Liu Xinqiao , Yang Zhisheng , Cheng Jinyong 
Published: April 2023

Abstract
Both sparsity and Cold-Start Problems are inevitably encountered in the music recommendation scenario. Auxiliary information have been utilized to music recommendation algorithms to offer users more accurate music recommendation results. This paper proposes an end-to-end framework MMSS_MKR, which uses the knowledge graph as a source of auxiliary information to serve the information obtained from it to the recommendation module. The framework exploits Cross & Compression Units to bridging the Knowledge Graph Embedding task and the recommendation task modules. We can obtain more realistic triple information and to exclude false triple information as far as possible since our model obtains the triple information through the music knowledge graph, and the information obtained through the recommendation module is used to determine the truth of the triple information.And thus, the knowledge graph embedding task is used to serve the recommendation task. In the recommendation module, multiple predictions are adopted to predict the accuracy of the recommendation. In the Knowledge Graph Embedding module, multiple calculations are used to calculate the score. Finally, the loss function of the model is improved to help us to obtain more useful information for music recommendation. The MMSS_MKR model achieves significant improvements in music recommendation over many existing recommendation models.
Identification and functional mechanism verification of key microRNAs associated with the fibrosis progression in chronic kidney disease
Authors: He Kaiying , Zhou Xiaochun , Zhao Jing , Du Hongxuan , university Yang He , Deng Rongrong , Wang Jianqin 
Published: April 2023

Abstract
Background: Chronic kidney disease (CKD) is a serious threat to human health worldwide, and its incidence is increasing annually. The incidence of CKD is a worldwide problem that heavily threatens human health and is increasing annually. A growing amount of information is emerging about the role of miRNAs in the regulation of renal fibrosis, which has aroused interest in the development of drugs that block pathogenic miRNAs or restore protective miRNAs levels.
Methods: The aim of this study was to identify the microRNAs (miRNAs) differentially expressed in renal tissues from patients with progressive DN and FSGS of high fibrosis scores to investigate the function and mechanism of miRNAs in renal fibrosis by using kidney tissues from normal and MCD patients as controls. First, we investigated the expression profiles of miRNAs in human kidney biopsy samples using microarray. Then, two new miRNAs were selected to explore the biological functions in TGF-β1 or HG -induced cell models using human proximal renal tubule cells (HK-2). GO and KEGG Pathway Enrichment Analysis were used to explore the target genes and their mechanism in renal fibrosis.
Results: The kidney biopsy samples from three types of diseases representing different fibrosis states, two novel miRNAs, hsa-miR-1470-3p and hsa-miR-4483-3p, were detected as consistently differentially expressed among all three types of patient's renal samples and in mice model. In vitro, hsa-miR-4483-3p was suppressed, whereas hsa-miR-1470-3p was induced by treatment with TGF-β1 or HG. Inhibition of hsa-miR-1470-3p or overexpression of hsa-miR-4483-3p promoted HG or TGF-β1-induced fibrosis in HK-2 cells. The further study revealed that MMP-13 and TIMP1 were the target genes of hsa-miR-1470-3p and hsa-miR-4483-3p, respectively.
Conclusion: In conclusion, the present study identifies newly dysregulated miRNA profiles related to fibrosis kidneys. Hsa-miR-1470-3p and hsa-miR-4483-3p are demonstrated to involve in kidney fibrosis by regulation of MMP13, TIMP1 respectively. Our results may represent a promising research direction for renal disorders and help identify new biomarkers and therapeutic targets for chronic kidney disease.
An online survey of women’s perceived care needs following miscarriage in hospital settings in Northern Ireland.
Authors: Galeotti Martina , Robinson Martin , Mitchell Gary , Tomlinson Mark , White Jonathan , Aventin Áine 
Published: April 2023

Abstract

Background
Miscarriage is a traumatic event for many women with significant psychological implications for women’s wellbeing. Women can experience anxiety, depression and post-traumatic stress disorder symptoms following their pregnancy loss. Health professionals are often the first point of contact when women experience symptoms of miscarriage but are not always equipped to meet women’s emotional needs. There is a lack of evidence on how best to support women who experience miscarriage within hospital facilities. This study aimed to fill this gap.
Methods
A survey was designed and distributed using social media targeting women who experienced miscarriage and attended any hospital facility in Northern Ireland. The survey included needs- and experience-focused questions and ‘The Revised Impact of Miscarriage Scale (RIMS)’. Demographic and experiential associations were analysed using Pearson’s correlation, between subjects t-test, and multiple regression.
Results
The results showed that miscarriage is associated with negative impacts on women’s emotional and psychological wellbeing. Many women perceived miscarriage as a devastating and isolating event. Further, this study highlighted the influence of socio- demographic and care-related risk factors on miscarriage experience.
Conclusions
Health professionals should consider a number of issues when interacting with women in hospital, particularly focusing on the emotional factors which can contribute to women’s distress. Although little can be done about socio-demographic factors from a health care point of view, it is still important to acknowledge those as risk factors. There is currently a lack of evidence-based interventions aimed at supporting women in hospital settings and further research should focus on the development of these.
Evaluating Patient and Otolaryngologist Dialogues Generated by ChatGPT, Are They Adequate?
Authors: Topsakal Oguzhan , Akinci Tahir Cetin , Celikoyar Mazhar 
Published: April 2023

Abstract
AI applications are becoming more and more prevalent each day. ChatGPT is a recent AI tool that has amazed many people with its capabilities. It is expected that large language model solutions like ChatGPT will provide unique solutions and transform many industries. In many medical educational institutions, it is desired that medical students experience simulated patient encounters before meeting with real patients. These simulations can be designed to closely mimic the experience of a real-life patient encounter, allowing students to practice communication and history-taking skills in a realistic setting. Designing dialogues for these simulations is an important and time-consuming challenge. In this study, we evaluate if ChatGPT, an AI tool based on GPT-3, can generate adequate patient-doctor dialogues that can be utilized for medical student training. We analyze patient-doctor dialogues generated by ChatGPT for ten common ENT diseases and discuss the pros and cons of these dialogues. We believe the patient-doctor dialogues provided by ChatGPT can be a good starting point for teaching medical students how to communicate with patients.
User Perception Simulation of Art Products Visual Design Based on VR Recognition
Authors: Hu Jiachong 
Published: April 2023

Abstract
The development of the computer is reflected in every aspect of life, and has actually changed people's life. Under the impact of computer technology, the traditional art design must be changed to adapt to the contemporary trend of The Times, so all kinds of digital art emerge in an endless stream. Whether it is drawing through computer technology, or using computer technology to carry out interactive virtual art design, or digital collections under the influence of the metauniverse, all show that computer technology has been deeply combined with art design. At the same time, the rapid economic development has greatly increased the demand for art products. The economic model that emphasized the market and production in the past has gradually evolved to a consumer-oriented economic model, bringing new opportunities and issues to the art design industry. This research centered on this issue investigates the use of the Internet of objects and visualization system technology. For example, the quality and efficiency of color vision can be improved by designing and supporting color visual effects, artistic product appearance, and design practices. The application and promotion of artistic product appearance design centered on convenient color-painting effects provide new methods and means for design. Through the Internet of Things technology and visual system art works, interactive contact with users can be made, thus redefining the relationship between artworks and viewers, and promoting the development of the art field in the information age.
A genomic instability-associated lncRNA signature for predicting prognosis and biomarkers in lung adenocarcinoma
Authors: Lin Chunxuan , Lin Kunpeng , Li Pan , Lin Xiaochun , Dai Yong , Liu Taisheng , Wei Chenggong 
Published: April 2023

Abstract

Genomic instability (GI) was associated with tumorigenesis. However, GI-related lncRNA signature (GILncSig) in lung adenocarcinoma (LUAD) is still unknown. In this study, the lncRNA expression data, somatic mutation information and clinical survival information of LUAD were downloaded from The Cancer Genome Atlas (TCGA) and performed differential analysis. Functional and prognosis analysis revealed that multiple GI-related pathways were enriched. By using univariate and multivariate Cox regression analysis, 5 GI-associated lncRNAs (AC012085.2, FAM83A-AS1, MIR223HG, MIR193BHG, LINC01116) were identified and used to construct a GILncSig model. Mutation burden analysis indicated that the high-risk GI group had much higher somatic mutation count and the risk score constructed by the 5 GI-associated lncRNAs was an independent predictor for overall survival (OS) (P < 0.05). Thus, we found that GI-associated lncRNAs may involve in progression and prognosis of LUAD. And targeting GI-associated lncRNAs may be an alternative for clinical therapy.