bluuebunny/crossref_metadata_2025_split huggingface dataset:
Selected Skill Sets as Building Blocks for High School-to-Medical School Bridge: Longitudinal Study Among Undergraduate Medical Students
Authors: Alsuwaidi Laila , Otaki Farah , Hassan Khamis Amar , AlGurg Reem , Lakhtakia Ritu 
Published: February 2023

Background
The high school–to–medical school education transition is a significant milestone in the students’ academic journey, which is characterized by multiple stressors. Although this crucial transition has been repetitively explored, the concept of proactively intervening to support this transition is still novel.

Objective
In this study, we investigated the efficacy of a web-based multidimensional resilience building intervention in developing selected soft skills that are believed to drive the learner’s success in any learning setting. The association between the students' academic performance over time and their proficiency in selected modules addressing skill sets, including Time Management, Memory and Study, Listening and Taking Notes, and College Transition, was also assessed to test the impact of the intervention on the students’ learning.

Methods
A longitudinal study was conducted on 1 cohort of students of a Bachelor of Medicine, Bachelor of Surgery program (MBBS). The medical students were offered a learning intervention around 4 skill sets during the first year of the 6-year program. Quantitative analyses were conducted using deidentified data, relating to the students' proficiency in the 4 skill sets and to the students’ academic performance: grade point average (GPA). Descriptive analyses constituted computing an overall score of skill sets’ proficiency (of all 4 selected skill sets). The mean and SD (and percentage of the mean) were also calculated for each skill set component, independently, and for the overall score of skill sets’ proficiency. Bivariate Pearson correlations were used to assess the extent to which the academic performance of the students can be explained by the corresponding students’ level of proficiency in each skill set component and by all 4 sets together.

Results
Out of the 63 admitted students, 28 participated in the offered intervention. The means and SDs of the annual GPA of the students for years 1 and 2 (GPA range 1-4) were 2.83 (SD 0.74) and 2.83 (SD 0.99), respectively. The mean and SD of the cumulative GPA toward the end of year 2 was 2.92 (SD 0.70). Correlation analysis showed that the overall score of skill sets proficiency was significantly associated with the annual GPA of year 1 (r=0.44; P=.02) but was not associated with their annual GPA of year 2. The cumulative GPA (toward the end of year 2) appeared to be significantly associated with the overall score (r=0.438; P=.02).

Conclusions
Developing purposefully selected skill sets among medical students holds the potential of facilitating the high school–to–medical school education transition and is likely to improve their academic performance. As the medical student progresses, the acquired skills need to be continuously reinforced and effectively built upon.
Investigation of the Trajectory of Muscle and Body Mass as a Prognostic Factor in Patients With Colorectal Cancer: Longitudinal Cohort Study
Authors: Seo Dongjin , Kim Han Sang , Ahn Joong Bae , Park Yu Rang 
Published: February 2023

Background
Skeletal muscle and BMI are essential prognostic factors for survival in colorectal cancer (CRC). However, there is a lack of understanding due to scarce studies on the continuous aspects of these variables.

Objective
This study aimed to evaluate the prognostic impact of the initial status and trajectories of muscle and BMI on overall survival (OS) and assess whether these 4 profiles within 1 year can represent the profiles 6 years later.

Methods
We analyzed 4056 newly diagnosed patients with CRC between 2010 to 2020. The volume of the muscle with 5-mm thickness at the third lumbar spine level was measured using a pretrained deep learning algorithm. The skeletal muscle volume index (SMVI) was defined as the muscle volume divided by the square of the height. The correlation between BMI status at the first, third, and sixth years of diagnosis was analyzed and assessed similarly for muscle profiles. Prognostic significances of baseline BMI and SMVI and their 1-year trajectories for OS were evaluated by restricted cubic spline analysis and survival analysis. Patients were categorized based on these 4 dimensions, and prognostic risks were predicted and demonstrated using heat maps.

Results
Trajectories of SMVI were categorized as decreased (812/4056, 20%), steady (2014/4056, 49.7%), or increased (1230/4056, 30.3%). Similarly, BMI trajectories were categorized as decreased (792/4056, 19.5%), steady (2253/4056, 55.5%), or increased (1011/4056, 24.9%). BMI and SMVI values in the first year after diagnosis showed a statistically significant correlation with those in the third and sixth years (P<.001). Restricted cubic spline analysis showed a nonlinear relationship between baseline BMI and SMVI change ratio and OS; BMI, in particular, showed a U-shaped correlation. According to survival analysis, increased BMI (hazard ratio [HR] 0.83; P=.02), high baseline SMVI (HR 0.82; P=.04), and obesity stage 1 (HR 0.80; P=.02) showed a favorable impact, whereas decreased SMVI trajectory (HR 1.31; P=.001), decreased BMI (HR 1.23; P=.02), and initial underweight (HR 1.38; P=.02) or obesity stages 2-3 (HR 1.79; P=.01) were negative prognostic factors for OS. Considered simultaneously, BMI >30 kg/m2 with a low SMVI at the time of diagnosis resulted in the highest mortality risk. We observed improved survival in patients with increased muscle mass without BMI loss compared to those with steady muscle mass and BMI.

Conclusions
Profiles within 1 year of both BMI and muscle were surrogate indicators for predicting the later profiles. Continuous trajectories of body and muscle mass are independent prognostic factors of patients with CRC. An automatic algorithm provides a unique opportunity to conduct longitudinal evaluations of body compositions. Further studies to understand the complicated natural courses of muscularity and adiposity are necessary for clinical application.
Safety of Sodium-Glucose Cotransporter-2 Inhibitors in Patients with CKD and Type 2 Diabetes: Population-Based US Cohort Study
Authors: Fu Edouard L. , D'Andrea Elvira , Wexler Deborah J. , Patorno Elisabetta , Paik Julie M. 
Published: February 2023

Background
Limited information exists regarding the safety of sodium-glucose cotransporter-2 inhibitors (SGLT2i) in patients with CKD treated in routine care. We evaluated the safety of SGLT2i in patients with CKD and type 2 diabetes treated in US routine practice.

Methods
Using claims data from Medicare and two large US commercial databases (April 2013–December 2021), we included 96,128 adults with CKD stages 3–4 and type 2 diabetes who newly filled prescriptions for SGLT2i versus glucagon-like peptide-1 receptor agonists (GLP-1RA). Safety outcomes included diabetic ketoacidosis (DKA), lower limb amputations, nonvertebral fractures, genital infections, hypovolemia, AKI, hypoglycemia, and severe urinary tract infections (UTIs). Hazard ratios (HRs) and incidence rate differences per 1000 person-years were estimated after 1:1 propensity score matching, adjusted for >120 baseline characteristics.

Results
Compared with GLP-1RA, SGLT2i initiators had a higher risk of nonvertebral fractures (HR, 1.30 [95% confidence interval (CI), 1.03 to 1.65]; incidence rate difference, 2.13 [95% CI, 0.28 to 3.97]), lower limb amputations (HR, 1.65 [95% CI, 1.22 to 2.23]; incidence rate difference, 2.46 [95% CI, 1.00 to 3.92]), and genital infections (HR, 3.08 [95% CI, 2.73 to 3.48]; incidence rate difference, 41.26 [95% CI, 37.06 to 45.46]). Similar risks of DKA (HR, 1.07 [95% CI, 0.74 to 1.54]; incidence rate difference, 0.29 [95% CI, −0.89 to 1.46]), hypovolemia (HR, 0.99 [95% CI, 0.86 to 1.14]; incidence rate difference, 0.20 [95% CI, −2.85 to 3.25]), hypoglycemia (HR, 1.08 [95% CI, 0.92 to 1.26]; incidence rate difference, 1.46 [95% CI, −1.31 to 4.23]), and severe UTI (HR, 1.02 [95% CI, 0.87 to 1.19]; incidence rate difference, 0.35 [95% CI, −2.51 to 3.21]) were observed. SGLT2i had lower risk for AKI (HR, 0.93 [95% CI, 0.87 to 0.99]; incidence rate difference, −6.75 [95% CI, −13.69 to 0.20]).

Conclusions
In US patients with CKD and type 2 diabetes receiving routine care, SGLT2i use was associated with higher risks of genital infections and potentially lower limb amputations and nonvertebral fractures.
Impact of habitat fragmentation on genetic structure of Capparis spinosa populations revealed by ISSR markers
Authors: Nosrati Houshang , Akbarian Hanife 
Published: February 2023

The results from empirical studies on the impact of habitat fragmentation on genetic variation of populations are controversial, ranging from negative to positive effects. This contradiction has been attributed to either species characteristics (e.g. plant life history) or environmental components (e.g. the scale of habitat fragmentation). To examine the role of DNA marker types on these effects, we carried out a comparative study of seven populations of Capparis spinosa L. (caper, Capparaceae) using ISSR markers and compared these results with those obtained previously using RAPD markers. Although both ISSR and RAPD markers showed high consistency and indicated that genetic variation in populations was not correlated with either geographical distance (P ≥ 0.47, P ≥ 0.83; for ISSR and RAPD, respectively) or altitude (P ≥ 0.535, P ≥ 0.419; for ISSR and RAPD respectively), the levels of variation were related to population size. ISSR analysis showed that genetic variation did not significantly differ between small and large populations (P ≥ 0.4149), while RAPD analysis indicated significant effect of population size on this variation (P ≤ 0.002). This may suggest that, in addition to species and environmental components, types of DNA markers used for assessing population genetic variations affect results on the impact of fragmentation on genetic variation.
Influence of Maturity Stages on Physicochemical Properties and Shelf-Life of Different Varieties of Mangoes under Ambient Storage Conditions
Authors: Bhuiyan Md. Shawkat H. , Hoque Md. Ahizizul , Hossain Md. Mofazzal , Zakaria Mohammad , Ahiduzzaman Md. 
Published: February 2023

The present investigation was carried out in the laboratory of the Department of Horticulture and Department of Agro-Preocessing, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur from May 2021 to July 2021 with three mango varieties viz. Langra, Amropali and Ashwina were harvested at different maturity stages to observe their storability under ambient conditions. The experiment was set up following a completely randomized design with three replications. Results revealed that the studied varieties had significant differences in physical characteristics such as fruit weight and chemical properties like total soluble solids, total sugar, and reducing sugar. Only the pH changes in the varietal and maturity stages were non-significant in this regard. In the case of variety at 12 days after storage, the total soluble solid content ranged from 17.54 to 20.04%. Total sugar content decreased but pH and reducing sugar increased as storage day increased in case of variety and maturity stage. Change of vitamin-C in maturity stage II and III at 4, 8, and 12 days after storage had no significant differences among them. The highest dry matter (19.72%) content was found on Amrapali (19.08%); on the other hand, maturity stage III had the highest (19.08%) value at 12 days after storage in this respect.
‘The Whiteness’ of Music Analysis. A Gloss on Philip Ewell's Lamentation over Schenker
Authors: Żerańska-Kominek Sławomira 
Published: February 2023

Abstract
The article is a polemic with the views formulated in 2020 by Philip A. Ewell in the Journal of the Society for Music Theory. His text is a critique of European music theory, mainly as represented in the writings by Heinrich Schenker. Ewell's main claim is that European music theory is based on racist concepts.
Rekayasa Cekaman Kekeringan Terhadap Pertumbuhan dan Hasil Tanaman Bunga Kol
Authors: Wati Asiah 
Published: February 2023

Prospek bunga kol (cauliflower) di Kalimantan timur sangat menjanjikan. Ditinjau dari aspek pemasaran kembang kol pada saat ini sangat tergantung dari luar daerah Kaltim (Jawa dan Sulawesi). Selain itu kembang kol juga mempunyai nilai ekonomi yang sangat tinggi di pasaran, sehingga budidaya kembang kol dalam skala komersial dan intensif akan dapat memberikan keuntungan yang tinggi.
Pada umumnya para petani beranggapan bahwa pembudidayaan tanaman kembang kol sangat rentan akan kegagalan panen. Salah satu kendala yang dihadapi dalam pembudidayaan kembang kol adalah keadaan cuaca. Salah satu cuaca yang mempengaruhi pertumbuhan yaitu curah hujan. Curah hujan yang menghasilkan air yang diserap oleh tanah dapat dimanfaatkan oleh tanaman sebagai alat bantu pengangkut unsur hara dari dalam tanah. Terpenuhinya unsur hara bagi tanaman akan meningkatkan produksi bunga kol.
Pada tahun 2009 rata-rata produksi tanaman kembang kol 247 ton. Tahun 2010 rata-rata produksi tanaman kembang kol mengalami penurunan menjadi 115 ton dan pada tahun 2011 rata-rata produksi tanaman kembang kol mengalami peningkatan menjadi 157 ton. Hal ini memperlihatkan produktivitas tanaman kembang kol di Kalimantan Timur masih rendah dikarenakan masih adanya ketidaktegasan cuaca terutama curah hujan. Agar dapat mengetahui toleransi tanaman bunga kol terhadap cekaman kekeringan maka dengan ini perlu dilakukan penelitian penelitian rekayasa cekaman kekeringan terhadap pertumbuhan dan hasil tanaman bunga kol. Metode penelitian menggunakan Rancangan Acak Lengkap (RAL) dengan perlakuan cekaman kekringan. Target luaran berupa publikasi artikel ilmiah di jurnal nasional ilmiah.

Kata kunci : perubahan iklim dan produksi.
Pertumbuhan & Produksi Bawang Merah (Allium cepa.L) Lokal Samosir Pada Berbagai Ukuran Wadah Dan Dosis Pupuk NPK
Authors: Husainah Yusuf  
Published: February 2023

Pertumbuhan dan Produksi Bawang Merah (Allium cepa L.) Lokal Samosir Pada Berbagai Ukuran Wadah dan Dosis NPK. Penelitian ini bertujuan untuk mengidentifikasikan bawang merah lokal samosir pada berbagai ukuran wadah dan dosis NPK. Penelitian ini dilaksanakan di Rumah Kaca Fakultas Pertanian Universitas Gunung Leuser, Aceh. Pada bulan April 2022-Juli 2022. Penelitian ini menggunakan Rancangan Acak Kelompok (RAK) dengan 2 faktor, yaitu ukuran wadah (15, 20, 25 dan 30) cm dan dosis NPK (0, 0.5, 1, 1.5 dan 2) gr. Parameter yang diamati yaitu panjang tanaman, jumlah daun, jumlah anakan, berat basah, diameter umbi dan berat kering. Hasil penelitian menunjukkan ukuran wadah secara nyata jumlah anakan. Jumkah anakan tertinggi diperoleh pada diameter 25 cm (W3), sedangkan jumlah anakan tertinggi diperoleh pada dosis NPK 0.5 g (N1), sedangkan interaksi antara perlakuan ukuran wadah dn dosis NPK tertinggi W2N3 (diameter 20 cm, NPK 1 g) sebesar 2.33.
SARS-CoV-2 molecular epidemiology in Slovenia, January to September 2021
Authors: Janezic Sandra , Mahnic Aleksander , Kuhar Urška , Kovač Jernej , Jenko Bizjan Barbara , Koritnik Tom , Tesovnik Tine , Šket Robert , Krapež Uroš , Slavec Brigita , Malovrh Tadej , Battelino Tadej , Rupnik Maja , Zohar Cretnik Tjasa ,   NLZOH COVID-19 team,   CISLD NGS team
Published: February 2023

Background
Sequencing of SARS-CoV-2 PCR-positive samples was introduced in Slovenia in January 2021. Our surveillance programme comprised three complementary schemes: (A) non-targeted sequencing of at least 10% of samples, (B) sequencing of samples positive after PCR screening for variants of concern (VOC) and (C) sequencing as per epidemiological indication.

Aim
We present the analysis of cumulative data of the non-targeted surveillance of SARS-CoV-2 and variant-dependent growth kinetics for the five most common variants in Slovenia for the first 9 months of 2021.

Methods
SARS-CoV-2 PCR-positive samples, from January to September 2021, were selected for sequencing according to the national surveillance plan. Growth kinetics studies were done on Vero E6 cells.

Results
Altogether 15,175 genomes were sequenced and 64 variants were detected, of which three successively prevailed. Variant B.1.258.17 was detected in ca 80% of samples in January and was replaced, within 9 weeks, by the Alpha variant. The number of cases decreased substantially during the summer of 2021. However, the introduction of the Delta variant caused a fourth wave and completely outcompeted other variants. Other VOC were only detected in small numbers. Infection of Vero E6 cells showed higher replication rates for the variants Alpha and Delta, compared with B.1.258.17, B.1.258, and B.1.1.70, which dominated in Slovenia before the introduction of the Alpha and Delta variants.

Conclusion
Information on SARS-CoV-2 variant diversity provided context to the epidemiological data of PCR-positive cases, contributed to control of the initial spread of known VOC and influenced epidemiological measures.
Strategi Pengembangan Usaha Tani Sayuran Berbasis Pertanian Organik
Authors: Septiadi Dudi , Mundiyah Andi Iva 
Published: February 2023

Penelitian ini bertujuan untuk, 1) menganalisis faktor internal dan eksternal dalam usaha tani sayuran berbasis organik pada Kelompok Tani Mekar Sari. 2) alternatif strategi pengembangan usaha tani sayuran berbasis pertanian organik. Penelitian ini dilakukan pada bulan Oktober hingga Desember 2019 pada Kelompok Tani Mekar Sari, yang memiliki usaha tani sayuran berbasis organik di Kecamatan Ampenan, Mataram. Jenis penelitian adalah penelitian deskriptif dengan pendekatan kualitatif. Data penelitian berasal dari lima orang responden kunci yang memiliki kepakaran pada usaha tani sayuran organik melalui wawancara dengan bantuan kuesioner, pengamatan langsung dan FGD pada perumusan alternatif strategi. Analisis data yang dengan SWOT menggunakan matriks IFE dan EFE serta Analisis Hierarki Proses pada perumusan strategi. Hasil penelitian berdasarkan analisis IFE hubungan antara ketua dan anggota kelompok tani sangat baik. Variasi jenis sayur, kualitas sayuran menjadi kekuatan dalam pengembangan usaha tani. Keterbatasan modal, kurangnya pemahaman petani tentang pertanian organik menjadi kelemahan yang dihadapi oleh Kelompok Tani Mekar Sari. Berdasarkan hasil dari analisis EFE, faktor cuaca dan iklim, harga sarana produksi usaha tani yang relatif mahal menjadi ancaman bagi kelompok tani namun adanya dukungan pemerintah dan swasta serta adanya asosiasi petani organik menjadi peluang bagi pengembangan usaha tani. Berdasarkan hasil analisis hierarki proses diperoleh alternatif strategi yakni bantuan modal kerja dan berbagi pengetahuan untuk meningkatkan minat petani terhadap pertanian organik dan melakukan kontrak kerja sama dengan pemerintah dam swasta dalam penyediaan sayuran organik pada kegiatan yang diselenggarakan di Mataram menjadi alternatif strategi dengan nilai tertinggi untuk rekomendasi kebijakan pengembangan usaha tani sayuran berbasis pertanian organik di masa yang akan datang.
Pengaruh Harga Dan Biaya Terhadap Pendapatan Petani Ubi Jalar Kecamatan Rumbia Kabupaten Jeneponto
Authors: Asriadi Andi Amran 
Published: February 2023

Penelitian bertujuan untuk mengetahui seberapa besar pengaruh harga dan biaya terhadap pendapatan petani ubi jalar Kecamatan Rumbia Kabupaten Jeneponto. Populasi dalam penelitian ini adalah petani ubi jalar yang berjumlah 300 orang. Untuk mendapatkan jumlah sampel penelitian ini sebanyak 30 orang diambil sebanyak 10 % penentuan sampel penelitian ini dilakukan dengan cara sengaja (Purposive Sampling). Hasil penelitian menunjukkan bahwa tingkat harga berpengaruh dan signifikan terhadap pendapatan petani ubi jalar di Kecamatan Rumbia Kabupaten Jeneponto, dengan nilai thitung (11.932) > ttabel (2,042) dengan signifikan, sehingga menjadikan hipotesis dalam penelitian ini Ho ditolak Ha diterima. Sedangkan biaya berpengaruh dan signifikan terhadap pendapatan petani dengan nilai thitung (-5.301)< ttabel (2,042). menjadikan hipotesis dalam penelitian ini Ho diterima Ha ditolak.
Analisis Penawaran Ekspor Crude Palm Oil (CPO) Indonesia ke China (Pendekatan Error Correction Model)
Authors: Nurcahyani Marizha 
Published: February 2023

Beragam penggunaan minyak nabati pada makanan menyebabkan permintaan cenderung meningkat setiap tahunnya. CPO merupakan salah satu minyak nabati yang paling banyak dikonsumsi di dunia. Salah satu produsen terbesarnya adalah Indonesia dengan salah satu konsumennya adalah China. Penelitian ini dilakukan untuk menganalisa faktor- faktor yang memengaruhi ekspor CPO Indonesia ke China pada tahun 1990 sampai 2015. Metode yang digunakan adalah metode Error Correction Model (ECM) untuk mengetahui faktor yang berpengaruh pada jangka panjang dan jangka pendek. Variabel yang diamati yaitu volume ekspor CPO Indonesia oleh China dengan faktor yang memengaruhi antara lain waktu, harga CPO Internasional, harga barang subsitusi (minyak kedelai), dan bea ekspor (Malaysia dan Indonesia). Hasil analisis menunjukkan bahwa volume ekspor CPO Indonesia ke China dipengaruhi oleh bea ekspor CPO Indonesia secara negatif dan signifikan baik dalam jangka panjang maupun pendek.
Analisis Faktor-Faktor Yang Memengaruhi Pengeluaran Rumah Tangga Petani Padi Sawah di Kabupaten Aceh Utara
Authors: Martina Martina , Praza Riyandhi , Adhiana Adhiana 
Published: February 2023

Kabupaten Aceh Utara merupakan wilayah sentra produksi padi sawah di Provinsi Aceh dengan luas tanam mencapai 75.800 Ha dengan produksi 389.945,41 ton. Sebagian besar masyarakatnya memiliki pekerjaan sebagai petani padi sawah. Jumlah penduduk Kabupaten Aceh Utara sebanyak 556.566 jiwa, dan sekitar 27,56 persen merupakan penduduk miskin. Kesejahteraan rumah tangga petani dapat diketahui dari besarnya pengeluaran rumah tangga petani padi sawah yang dipengaruhi oleh beberapa faktor antara lain pendapatan, luas lahan usaha tani, jumlah tanggungan, jumlah anak yang masih sekolah, dan umur kepala keluarga. Penelitian ini bertujuan untuk menganalisis faktor-faktor yang memengaruhi pengeluaran rumah tangga petani padi sawah di Kabupaten Aceh Utara. Responden dalam penelitian ini sebanyak 60 kk dengan analisis data mengunakan model analisis regresi linier berganda. Hasil penelitian menunjukkan bahwa secara simultan variabel pendapatan, luas lahan, jumlah tanggungan, jumlah anak masih sekolah, dan umur kepala keluarga berpengaruh signifikan terhadap pengeluaran rumah tangga petani padi sawah di Kabupaten Aceh Utara, sedangkan secara parsial hanya variabel pendapatan dan jumlah tanggungan yang berpengaruh signifikan terhadap pengeluaran rumah tangga petani padi sawah