bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of retardation and capillarity on organic contaminant diffusion through an unsaturated composite liner: An analytical approach
Authors: Liu Jun , Chen Zhang‐Long , Yu Chuang , Wang Shun , Wu Wei 
Published: May 2023

AbstractIn unsaturated composite liners, the heterogeneous distribution of water content and capillarity are common phenomena with remarkable influence on the transport parameters. This study presents an analytical solution to assess the effect of unsaturation‐dependent retardation and capillarity on the organic contaminant diffusion through an unsaturated composite liner. The solution is obtained by the generalized integral transform technique and is verified against other analytical and numerical solutions. Particular attention is paid to the potential errors in predicting organic contaminant transport caused by unsaturation‐independent retardation factor assumption. The results show that neglecting saturation‐dependent retardation may cause considerable errors. The considerations of capillary fringe and degradation also have significant effects on the errors. In addition, a simplified solution based on a new averaged retardation factor is proposed and its performance is evaluated.
Non‐histone protein methylation in Trypanosoma cruzi epimastigotes
Authors: de Almeida Rafael Fogaça , Lucena Aline Castro Rodrigues , Batista Michel , Marchini Fabricio Klerynton , de Godoy Lyris Martins Franco 
Published: May 2023

AbstractPost‐translational methylation of proteins, which occurs in arginines and lysines, modulates several biological processes at different levels of cell signaling. Recently, methylation has been demonstrated in the regulation beyond histones, for example, in the dynamics of protein‐protein and protein‐nucleic acid interactions. However, the presence and role of non‐histone methylation in Trypanosoma cruzi, the etiologic agent of Chagas disease, has not yet been elucidated. Here, we applied mass spectrometry‐based‐proteomics (LC‐MS/MS) to profile the methylproteome of T. cruzi epimastigotes, describing a total of 1252 methyl sites in 824 proteins. Functional enrichment and protein‐protein interaction analysis show that protein methylation impacts important biological processes of the parasite, such as translation, RNA and DNA binding, amino acid, and carbohydrate metabolism. In addition, 171 of the methylated proteins were previously reported to bear phosphorylation sites in T. cruzi, including flagellar proteins and RNA binding proteins, indicating that there may be an interplay between these different modifications in non‐histone proteins. Our results show that a broad spectrum of functions is affected by methylation in T. cruzi, indicating its potential to impact important processes in the biology of the parasite and other trypanosomes.
Proteome profiling of vascular sap regarding Eucalyptus grandis, Eucalyptus urophylla, and Eucalyptus camaldulensis
Authors: da Silva Felipe Alexsander Rodrigues , Balbuena Tiago Santana 
Published: May 2023

AbstractThe plant vascular system is a key element for long‐distance communication. Understanding its composition may provide valuable information on how plants grow and develop themselves. In this study, a quantitative proteome dataset of the vascular sap proteome of three commercially important Eucalyptus species was shown. Protein extraction was carried out using a pressure bomb, whereas only in silico predicted extracellular proteins were considered as part of the sap proteome. A total of 132 different proteins were identified in all three Eucalyptus species and the most abundant proteome subset within all three species was comprised of proteins involved in the carbohydrate metabolic process, proteolysis, components of membrane, and defense response. The sap proteome of the species E. grandis and E. urophylla revealed the highest similarities. Functional classification indicated that the sap proteome of E. grandis and E. urophylla are mostly comprised of proteins involved in defense response and proteolysis; whereas no prominent functional class was observed for the E. camaldulensis species. Quantitative comparison highlighted characteristic sap proteins in each of the Eucalyptus species. The results that could be found in this study can be used as a reference for the proteome sap analysis of Eucalyptus plants grown under different conditions.
Economic and financial model to the mass‐rearing of Macrolophus pygmaeus (Rambur) (Heteroptera: Miridae), a biological control agent against the tomato moth Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae) in protected culture
Authors: Dutra Tiago Mota , da Graça Batista Maria , Teixeira João CA , Todorova Silvia , Oliveira Luísa , Tavares João , Borges Isabel , Soares António Onofre 
Published: May 2023

AbstractBACKGROUNDTuta absoluta (Meyrick) is a major pest of tomato produced in glasshouses and open field, causing severe damages to crops, reducing the quality of tomato fruits. The current maintenance of the pest populations below the economic threshold is not achieved by natural and classical control, thus requiring the continuous application of biological control agents (BCAs), under an augmentative or inoculative approach. The present study aims to develop an economic and financial model to evaluate the commercial viability of a continuous mass production of Macrolophus pygmaeus (Rambur), a BCA commonly used against the tomato moth, Tuta absoluta, in protected culture. The estimations for our model were based on two approaches: the farm‐level impact analysis and the benefit–cost analysis.RESULTSThe results of the farm‐level analysis show that the adoption of a more sustainable biological control approach is profitable for farmers and the benefit–cost analysis provides evidence that the investment on a new factory dedicated to the mass rearing of M. pygmaeus to control tomato moth populations generates a positive net present value (NPV) of 7.2 million euros, corresponding to an internal rate of return (IRR) of 28.4% per year.CONCLUSIONOur results are in line with (i) the more recent European Commission proposals for a new Regulation on sustainable use of plant protection products, which includes the reduction of 50% the use and risk of chemical pesticides by 2030 and (ii) most of the existing literature which conclude that new projects on BCA production are worth investments. © 2023 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Human gingival tissue‐derived mesenchymal stem cells inhibit proliferation and invasion of rheumatoid fibroblast‐like synoviocytes via the CD39/CD73 signaling pathway
Authors: Chen Weiqian , Yu Ye , Zheng Song Guo , Lin Jin 
Published: May 2023

AbstractBackgroundGingiva‐derived mesenchymal stem cells (GMSCs) suppress immune and inflammatory responses in experimental arthritis models. Here, we determined whether GMSCs suppress the proliferation and invasion of rheumatoid arthritis fibroblast‐like synoviocytes (RA FLSs).MethodsSurface markers of GMSCs were analyzed by flow cytometry. mRNA expression of matrix metalloproteinases and pro‐inflammatory cytokine in RA FLSs was measured by quantitative polymerase chain reaction (PCR). RA FLS proliferation was analyzed by a 5‐ethynyl‐2′‐deoxyuridine assay. To explore the molecular mechanisms, we assessed the effect of GMSCs on RA FLS proliferation by adding indoleamine‐2,3‐dioxygenase (IDO), CD39, or CD73 inhibitors. The invasion was analyzed by a transwell assay. The anti‐inflammatory effects of GMSCs were assessed in a type II collagen‐induced arthritis (CIA) mouse model.ResultsCompared with human dermal fibroblast, GMSCs displayed a higher expression of CD39. Interleukin (IL)‐8, IL‐6, MMP‐1, MMP‐3, MMP‐13, and monocyte chemoattractant protein‐1 mRNA were all decreased in RA FLSs after incubation with GMSCs. GMSCs significantly reduced RA FLS proliferation in a dose‐dependent manner in vitro, which was partly dependent on CD39/CD73 signaling. GMSCs significantly impeded the invasive capacity of RA FLSs in a dose‐dependent manner in vitro. GMSCs infusion delayed arthritis onset and reduced arthritis scores in the CIA model.ConclusionGMSCs are effective to inhibit the aggressive behavior of RA FLSs and treat experimental arthritis, implying their therapeutic potential in RA patients.
C/H/O stable isotope of rape honey and its components combined with machine learning algorithms to identify geographical origin
Authors: Shuai Mengying , Li Hongxia , She Seng , Wu Meijia , Chen Lanzhen 
Published: May 2023

RationaleThe distribution of rape honey is among the largest and most diverse of all honeys available to humankind with respect to the geographical origin. Accurate isotopic reference values for rape honey are therefore important for precise verification of honey origin and its traceability. New combined rape honey δ13C, δ2H, and δ18O values in combination with values on its compounds (protein and saccharides) were used to complement existing databases to better identify the geographical origin of Chinese rape honey.MethodsTraceability methods based on elemental analyzer isotope ratio mass spectrometry and liquid chromatography isotope ratio mass spectrometry were established for geographical origin of rape honey.ResultsRape honey harvested in the high‐altitude region (QH; Qinghai) had significantly higher values (1.4 to 5.3‰ for δ13C, 7.9 to 12.9‰ for δ2Hprotein) for the δ13C of whole honey (−23.8‰), its protein (−24.4‰), fructose (−23.5‰), glucose (−23.6‰), and disaccharide (−24.7‰), and also δ2H of the protein (103.5‰) than those in low‐altitude regions (HB; Hubei, SC; Sicuan, and JS; Jingsu). The δ18Orape honey was a useful index to differentiate whether rape honey from coastal (JS) or non‐coastal (HB, SC, and QH) regions. The δ13C, δ2H, and δ18O values in rape honey are affected by geographical factors, such as temperature and altitude. The δ13Cprotein and δ13Crape honey values were better to identify the geographical origin of rape honey than δ13Csaccharides. The δ18O and δ2H values of rape honey protein were more suitable for traceability than those of rape honey. The combination of the δ13C, δ2H, and δ18O values of rape honey and its extracted protein and saccharides improved the precision of three models (linear discriminant analysis, SVM, and random forest) used to discriminate rape honey from different regions in China. The SVM model obtained the best accuracy (93.2%).ConclusionsStable isotopes could be significant predictors in determining the geographical origin of rape honey.
Consensus of nonlinear multi‐agent systems via distributed hybrid controls
Authors: Wei Linna , Liao Yihao , Luo Shixian , Chen Wu‐Hua , Huang Ganji 
Published: May 2023

AbstractThe consensus problem of nonlinear multi‐agent systems with nonuniform time‐varying connection topologies via two novel distributed hybrid control protocols is discussed. By using the degrees of freedom brought by coupling weights, impulsive control with impulse time windows integrates intermittent control and impulsive control into a unified control framework and is more suitable for the situations where only the time intervals in which impulses occur are known but the exact instants of impulses cannot be identified. Compared with intermittent control, the intermittent impulsive control (IIC) reduces the amount of data transmission and improves the security of the system. The introduction of the rest windows makes the IIC break the limit of the upper bound of impulsive intervals of general impulsive control, and the system is easier to maintain according to plan. Control‐time‐dependent Lyapunov function based methods are developed to overcome the difficulty of stability analysis of the error systems caused by continuous switching of multiple dynamic subsystems. Two consensus criteria are presented and the corresponding controller design schemes are proposed. The results can uniformly deal with the positive and negative effects of impulses, and do not require at least one subsystem of the error system to be stable. Three examples are given to demonstrate the effectiveness of the derived theoretical results.
Relations Between Reading Motivation and Reading Efficiency—Evidence From a Longitudinal Eye‐Tracking Study
Authors: Rettig Anja , Schiefele Ulrich 
Published: May 2023

AbstractStudies on the relation between children's reading motivation and early developmental stages of reading competence are rare and have neglected on‐line measures of reading skill (e.g., eye movements indicating word decoding). For this reason, we investigated the effects of intrinsic and extrinsic reading motivation on the efficiency of reading processes based on eye‐movement data. Moreover, we examined reading efficiency as a mediator of the relation between motivation and comprehension. German elementary school students in Grades 1–3 (N = 131) were tested on three measurement occasions. Specifically, we assessed reading motivation, reading amount, and sentence comprehension at Time 1, reading efficiency at Time 2 (2 months after Time 1), and all of the variables again at Time 3 (10 months after Time 2). Reading efficiency was assessed while children read age‐appropriate sentences and comprised measures of first‐fixation duration, gaze duration, total reading time, forward‐saccade length, and refixation probability. Linear and cross‐lagged panel models showed significant favorable relations between intrinsic reading motivation (operationalized as involvement and enjoyment of reading), but not extrinsic reading motivation (operationalized as striving to outperform one's peers), and most measures of reading efficiency, while controlling for gender, grade level, and reading amount. The reverse effects of reading‐efficiency indicators on intrinsic reading motivation were all significant. Moreover, the test of the mediation model revealed a significant indirect effect of Time 1 intrinsic reading motivation on Time 3 sentence comprehension mediated by Time 2 reading efficiency. We concluded that intrinsic reading motivation, in contrast to extrinsic reading motivation, facilitates reading comprehension through its effect on reading efficiency, independent of variations in reading amount.
Comprehensive evaluation and stability analysis of ecosystem quality of Yellow River Basin during 1980–2019
Authors: Cao Zhiwei , Ma Wensi , Zhang Chao , Tan Peiying 
Published: May 2023

AbstractQuality and stability are the basic characteristics of ecosystems, reflecting their structure, process, functional integrity, ability to resist disturbance, self‐regulation, and dynamic balance. The quantitative description of ecosystem quality and stability is an indispensable and important task to promote the ecological protection and high‐quality development of the Yellow River Basin as a major national strategy. In this study, an index evaluation system was constructed from the perspective of system governance, considering the special characteristics of the Yellow River Basin, and an entropy weight model was used to establish a multi‐indicator long time series ecosystem quality evaluation index (EQI) to quantitatively describe the ecological quality changes in the Yellow River Basin over 40 years. The dissipative structure theory and Brussels apparatus model were used to establish quantitative indicators and methods, and provide ideas for the study of ecosystem homeostasis transformation in the Yellow River basin. This study found that: (1) the average EQI value of the Yellow River Basin ecosystem for 40 years was 63.96, the maximum and minimum values were 69.65 and 59.45, respectively; the overall quality showed an oscillating trend of improvement, with an annual increase of 0.03, and the spatial distribution was better in the downstream than in the midstream, and in the midstream than in the upstream; (2) The key factors influencing the system changed gradually from the total water consumption and total annual precipitation in the basin in the early stage to the average income of residents in the last 10 years. (3) The system steady‐state transition force values from 1980 to 2019 were all <0, the steady‐state conversion force of the Yellow River Basin ecosystem was low, but the overall trend was oscillating upward, and the overall trend was getting closer to the critical condition of steady‐state conversion.
Sudden Onset Anhidrosis in an Otherwise Healthy Male
Authors: Tan Clara Michelle Tan Hwei Sian , Lee Rayson , Pei Ling Dua Janet 
Published: May 2023

Abstract
Acquired idiopathic generalised anhidrosis (AIGA) is a rare disorder that is characterised by sudden onset generalised absence of sweating without any dermatological, neurological or sweat gland abnormalities. AIGA predominately affects young males, mostly involving patients of Asian descent. There have been approximately 100 reported cases worldwide, most of which were reported in Japan. In Singapore, it is rarely seen with one case series on 15 cases of AIGA reported in a 2014 study. Here, we present a case of AIGA who responded well to conservative management with sweating activity.
An Ion Selective Electrode Construction Based on Phosphomolybdic Acid for Atropine Sulfate Detection
Authors: Hamad Omer Q. , Karim Wrya O. 
Published: May 2023

AbstractThis study presents an attempt has been carried out to fabricate ion‐selective electrodes (ISEs) for the determination of Atropine sulfate (AT) in pharmaceutical formulas. Three plasticizers; namely, di‐n‐butyl phthalate (DBP), bis (2‐ethyl hexyl) phthalate (BEP), nitrobenzene (NB), and tetrahydrofuran (THF) were used in the fabrication of the three ion selective electrodes after incorporating into polyvinyl chloride (PVC) and symbolized as E1, E2, and E3, respectively. Beyond evaluation of the three ISEs, it has been confirmed that one with DBP experienced the most Nernstian behaviour. For the electrode of interest, the slope and detection limit are 55.02 mV/decade and 1.1×10−6 M, respectively. The linear range was 1.0×10−2–1.0×10−5 M (R2=0.9999) with recording 5 s and 45 days; sequentially, for the response time and shelf life of E1 electrode. The sensor has experienced high selectivity for atropine sulfate, verifying from the selectivity coefficient data for a number of potential interferences. The statistical analysis usingt‐test andF‐test indicates the eligibility of constructed electrode for utilization in field of pharmaceutical analysis. A satisfactory accordance has been obtained between the proposed electrode for atropine sulfate and the standard method. This methodology is supposed to be applicable in quality control and even clinical diagnosis.
Preparation and Performance of A Lime‐Preconditioned Phosphogypsum/Ag‐based Bacteriostatic Composite by Highly Efficient Loading of Ag (I) from Wastewater
Authors: Tu Junhong , Deng Qiulin , Luo Chenli , Zeng Boli , Deng Hongquan , Zhang Tao , Shi Lianjun , Zhang Hong , Dong Faqin 
Published: May 2023

AbstractThis work was supported by the Natural Science Foundation of Southwest University of Science and Technology (15zx7125); the Foundation of Post‐doctoral Scientific Research Station of Wengfu (Group) Co., Ltd. (YF(2020)022); the Foundation of National & Local Joint Engineering Research Center for Mineral Salt Deep Utilization (SF201906); the Sichuan Science and Technology Program (2023YFS0359); and the Undergraduate Innovation Fund Project Precision Funding Program by Southwest University of Science and Technology (s202210619057, 22XCY057)
Next steps: Operationalizing resilience research
Authors: Brown LaVerne , Cohen Barbara , Costello Rebecca , Brazhnik Olga , Galis Zorina S. 
Published: May 2023

AbstractThe National Institutes of Health have recently gathered internal and external input towards a shared understanding of resilience in the wide context of human health and the biomedical sciences that would help accelerate advances in human health and its maintenance. We suggest the current view that resilience refers in general to a system's capacity to recover, grow, adapt, or resist perturbation from a challenge or stressor. To help harmonize the design and reporting of resilience research studies across multiple domains we have developed and are proposing a Resilience Research Design (ResD) Tool. Researchers can use the Resilience ResD Tool to proceed through a flowchart of six questions that will guide identification of key features in a resilience research study. Through this special supplement, we have shown the application of the Resilience ResD Tool and suggest opportunities and gaps with respect to next steps towards operationalizing resilience research.
Functionalized Metal–Organic Framework‐Modified Hydrogel That Breaks the Vicious Cycle of Inflammation and ROS for Repairing of Diabetic Bone Defects
Authors: Lao An , Wu Jiaqing , Li Dejian , Shen Aili , Li Yaxin , Zhuang Yu , Lin Kaili , Wu Jianyong , Liu Jiaqiang 
Published: May 2023

AbstractThe regeneration of diabetic bone defects remains challenging. Hyperglycemia causes inflammation state and excessive reactive oxygen species (ROS) during bone regeneration period. These two effects reinforce one another and create an endless loop that is also accompanied by mitochondrial dysfunction. However, there is still no effective and inclusive method targeting at the two aspects and breaking the vicious cycle. Herein, nanoparticles‐Met@ZIF‐8(metformin loaded zeolitic imidazolate frameworks) modified hydrogel that is capable of releasing metformin and Zn elements are constructed. This hydrogel treats hyperglycemia while also controlling mitochondrial function, reducing inflammation, and restoring homeostasis. In addition, the synergetic effect from metformin and Zn ions inhibits ROS‐inflammation cascade generation and destroys the continuous progress by taking effects in both ROS and inflammation and further keeping organelles’ homeostasis. Furthermore, with the recovery of mitochondria and breakdown of the ROS‐inflammation cascade cycle, osteogenesis under a diabetic microenvironment is enhanced in vivo and in vitro. In conclusion, the study provides critical insight into the biological mechanism and potential therapy for diabetic bone regeneration.
Ting, tang, tong: Emergent bilingual students investigating and constructing evidence‐based explanations about sound production
Authors: Suárez Enrique , Otero Valerie 
Published: May 2023

AbstractThere is a significant amount of research literature on the importance of identifying and building on students' experiences and ideas for making sense of the natural world, especially when engaging in science practices. Simultaneously, approaches to creating justice‐oriented science education promote the need to focus on the diverse sense‐making repertoires that students, especially those from historically marginalized communities, bring to science classrooms. However, when it comes to emergent bi/multilingual students, science education has favored narrow definitions of what ways of communicating are seen as productive for figuring out natural phenomena, privileging English‐based academic vocabulary. In this article, we investigate the myriad conceptual and semiotic resources that third‐grade emergent bilingual students developed and used when explaining sound production. Additionally, we explore how students investigated the sounds produced by a string instrument and unpacked the how and whys that give rise to the pitch of the sounds they heard. Our analyses indicate that: (1) students created mechanistic explanations that identified how changes to the salient physical features of strings affected the pitch of the sounds; (2) students created and laminated multiple semiotic resources when sharing their observations and explanations, particularly sound symbolisms; and (3) students navigated both semiotic convergence and divergence as they worked toward conceptual convergence. Based on our findings, we argue that justice‐oriented science learning environments must become spaces where emergent bilingual students can build on all their conceptual, semiotic, and cultural resources, without being policed, as they engage science practices.