bluuebunny/crossref_metadata_2025_split huggingface dataset:
Marketing of Fine Art on the Way from Ancient Times to Art Market of the XXI Century
Authors: Akimov Dmytro 
Published: September 2023

The purpose of the study is to study and analyse the history of the development of marketing technologies in the fine arts market throughout human history from ancient times to the beginning of the XXI century. The research methodology is based on the use of comparative, empirical, and theoretical methods. This methodological approach allows to analyse the process of formation and history of development of fine art marketing, to conduct a study of marketing processes in the promotion of works of art in the art market at different times of human history. The scientific novelty is to expand the understanding of the fine art market. The article examines marketing processes in the art market at different historical times. The article analyses the problems that have been formed and overcome throughout the history of the emergence and formation of marketing in the field of culture and art. The article also analyses the theoretical foundations of fine art marketing and the ways of their practical implementation in different periods of art market formation. Conclusions. The conducted analysis allowed to determine that even before the emergence of the modern art market as an element of the general capitalist market, the movement of works of fine art thousands of years ago, in ancient times, contained elements of marketing approaches and technologies, which was entirely due to the processes of selling and buying works of art, exchanging them and collecting them. In particular, we are talking about the forerunners of marketing approaches and technologies aimed at satisfying the public demand for works of fine art; organising the collection, classification and collecting of works of fine art; conducting an examination of their quality and originality; determining the methods of promoting works in society that were already available at that time. Thus, before the emergence of the modern art market, there was a so-called "wild market" that in a certain way "regulated" the processes of movement of works of art in society.
Key words: art marketing, art market, "wild market" of art works, marketing technologies.
Artificial Intelligence in Acoustics of Library Functioning in Ukraine
Authors: Ivashkevych Olga 
Published: September 2023

The purpose of the study is to outline achievements, prospects for transformation and identify obstacles to the implementation of systems, elements of artificial intelligence (AI) and the algorithm for overcoming them in national library and information institutions. Research methodology: the principles of systematicity, generalisation, objectivity, and general methods of scientific research – analysis, synthesis, comparison, analytical monitoring of AI elements in libraries of the country – are applied. The scientific novelty of the work is to highlight, with an emphasis on key aspects, the obstacles to the addition of AI intellectual resources to the work of libraries in the realities of today. Conclusions. The article reflects the developments, main areas of use and reasons for limiting the intensive integration of AI systems and elements into library practice. Features of the application of AI components, practical potential of ultra-high-frequency technologies in national libraries. The above-mentioned practice in libraries is especially relevant during martial law and the times of profound changes. It will facilitate public access to information and self-education; access to advanced technological developments; allow further steps in the formation of a new digitalisation focus of libraries and modification of library activities; thoroughly form an approach to the vectors of the industry's influence on society; innovations in the model of library-user relations, taking into account civilisation challenges. The studied trends in the addition of intelligent systems and elements of artificial intelligence will contribute to the voluntarisation of technological proposals in library and information institutions. As a result of the study, the issue of compatibility of adding intellectual components to the work of the library industry with the realities of the country and the corresponding algorithm of actions for the long-term is considered.
Key words: library, systems and elements of artificial intelligence, innovative technologies, transformation of intellectual resources, challenges of AI implementation in library practice.
The Economic Measurement of Cyber Incidents
Authors: Szádeczky Tamás , Bederna Zsolt 
Published: September 2023

In recent decades, Information and Communication Technologies (ICT) have significantly evolved, further establishing the information society. However, ICT systems are subject to security incidents, and most malicious attacks have cascading effects. Decision-makers need to understand the potential financial effects of incidents if they wish to clearly perceive the potential risks and thus make an appropriate allocation of resources to ICT security.Our research attempts to develop a comprehensive toolset for the analysis of cybersecurity incidents. The toolset is based on conventional methodologies of cash-flow evaluation and balance of payments. We discuss several use cases of real-world examples with incidents affecting essential service providers and manufacturers. The case studies involve incidents affecting energy service providers, banks, water utilities, aircraft manufacturers, car manufacturers, IT software providers, air, rail, and water transport companies, the pharmacy, and the health sector. Analysis of the incidents involves our framework being applied at three levels: organisational, governmental, and international.
Manejo de la hernia inguinal mediante TAPP (hernioplastia transabdominal preperitoneal)
Authors: Carrillo López David Gonzalo , Verdugo Tapia Juan Carlos 
Published: September 2023

Resumen Introducción. Se estima que entre el 10% y el 15% de la población mundial actualmente presenta o presentará una hernia en la pared abdominal, siendo el 60% de estas hernias específicamente en la región inguinal y con un riesgo vitalicio de padecer una hernia inguinal entre el 27% al 43% en hombres La cirugía mínimamente invasiva, entre estas la hernioplastia inguinal, se ha convertido en uno de los procedimientos quirúrgicos más comunes a nivel mundial. Actualmente, la técnica laparoscópica se ha convertido en una opción para el reparo de la patología herniaria. Los resultados han sido favorables debido al uso de mallas libres de tensión. Objetivo. Describir el manejo de la hernia inguinal por medio de la técnica laparoscópica transabdominal preperitoneal. Metodología. Se realizó una revisión bibliográfica narrativa de revisiones sistemáticas, metaanálisis y revisiones bibliográficas en el idioma inglés y español, recopilados en bases de datos como PubMed, LILACS y Medline, publicados en los últimos 5 años, en humanos, mayores de 19 años. Resultados. Este análisis abordo el enfoque del manejo de hernia inguinal mediante la técnica de hernioplastia transabdominal preperitoneal, basándose en la revisión y análisis de 15 investigaciones, tras la aplicación de criterios de inclusión y exclusión. Los estudios aportaron datos sustanciales en relación a diversas complicaciones como seroma, hematoma e infección de la herida. Además, se exploraron complicaciones menos comunes y se evaluaron tanto las ventajas como las desventajas de emplear esta técnica, considerando también el impacto en términos de costos y la duración de la estancia hospitalaria. Este análisis comprehensivo brinda una perspectiva esencial sobre la eficacia y la viabilidad de la hernioplastia transabdominal preperitoneal. Conclusión. La hernioplastia transabdominal preperitoneal ofrece resultados positivos en. la recuperación del paciente, menor dolor post-operatorio y una probabilidad significativamente reducida de infecciones, permitiendo un retorno temprano a las actividades cotidianas y laborales, sin embargo, pueden surgir complicaciones tardías, como el dolor inguinal crónico y la recurrencia de la hernia. Área de estudio general: Medicina. Área de estudio específica: Cirugía General. Tipo de estudio: Revisión bibliográfica.
Dragonfly (Odonata) Specimens Collection of Bogor Botanical Garden
Authors: Rachmatiyah Rina , Pungki Lupiyaningdyah  
Published: September 2023

Dragonfly (Odonata) specimens that have been collected for 76 years (1929-2005) by the Bogor Botanical Gardens (BBG) and kept at the Zoologicum Bogoriense Museum (ZBM) are interesting to study because quite a number of these specimens have not been identified at the species taxon level. The research objective was to record and identify dragonfly species that once lived and were found flying in the BBG area and have become ZBM specimen collections. The research method used is by sorting, grouping, and identifying specimen collections. The identification results of dragonfly specimen collection showed that there were 1,357 specimens consisting of 7 families and 25 species. The most collected family was Libellulidae. The most collected species was Agriocnemis femina (311 specimens), followed by Crocothemis servilia (245 specimens), and Brachythemis contaminata (217 specimens). The year 1995 was the year with the highest number of specimens collected at 1,137 specimens. Garuda Park Pond, Building 9 Pond, Palace Pond, and inside the botanical garden area were the locations with the most dragonfly encounters.
Mimicking acute airway tissue damage using femtosecond laser nanosurgery in airway organoids
Authors: Gentemann Lara , Donath Sören , Seidler Anna E. , Patyk Lara , Buettner Manuela , Heisterkamp Alexander , Kalies Stefan 
Published: September 2023

Airway organoids derived from adult murine epithelial cells represent a complex 3D in vitro system mimicking the airway epithelial tissue’s native cell composition and physiological properties. In combination with a precise damage induction via femtosecond laser-based nanosurgery, this model might allow for the examination of intra- and intercellular dynamics in the course of repair processes with a high spatio-temporal resolution, which can hardly be reached using in vivo approaches. For characterization of the organoids’ response to single or multiple-cell ablation, we first analyzed overall organoid survival and found that airway organoids were capable of efficiently repairing damage induced by femtosecond laser-based ablation of a single to ten cells within 24 h. An EdU staining assay further revealed a steady proliferative potential of airway organoid cells. Especially in the case of ablation of five cells, proliferation was enhanced within the first 4 h upon damage induction, whereas ablation of ten cells was followed by a slight decrease in proliferation within this time frame. Analyzing individual trajectories of single cells within airway organoids, we found an increased migratory behavior in cells within close proximity to the ablation site following the ablation of ten, but not five cells. Bulk RNA sequencing and subsequent enrichment analysis revealed the differential expression of sets of genes involved in the regulation of epithelial repair, distinct signaling pathway activities such as Notch signaling, as well as cell migration after laser-based ablation. Together, our findings demonstrate that organoid repair upon ablation of ten cells involves key processes by which native airway epithelial wound healing is regulated. This marks the herein presented in vitro damage model suitable to study repair processes following localized airway injury, thereby posing a novel approach to gain insights into the mechanisms driving epithelial repair on a single-cell level.
Hypervalent hydridosilicate in the Na–Si–H system
Authors: Spektor Kristina , Kohlmann Holger , Druzhbin Dmitrii , Crichton Wilson A. , Bhat Shrikant , Simak Sergei I. , Vekilova Olga Yu , Häussermann Ulrich 
Published: September 2023

Hydrogenation reactions at gigapascal pressures can yield hydrogen-rich materials with properties relating to superconductivity, ion conductivity, and hydrogen storage. Here, we investigated the ternary Na–Si–H system by computational structure prediction and in situ synchrotron diffraction studies of reaction mixtures NaH–Si–H2 at 5–10 GPa. Structure prediction indicated the existence of various hypervalent hydridosilicate phases with compositions NamSiH(4+m) (m = 1–3) at comparatively low pressures, 0–20 GPa. These ternary Na–Si–H phases share, as a common structural feature, octahedral SiH62− complexes which are condensed into chains for m = 1 and occur as isolated species for m = 2, 3. In situ studies demonstrated the formation of the double salt Na3[SiH6]H (Na3SiH7, m = 3) containing both octahedral SiH62− moieties and hydridic H−. Upon formation at elevated temperatures (&gt;500°C), Na3SiH7 attains a tetragonal structure (P4/mbm, Z = 2) which, during cooling, transforms to an orthorhombic polymorph (Pbam, Z = 4). Upon decompression, Pbam-Na3SiH7 was retained to approx. 4.5 GPa, below which a further transition into a yet unknown polymorph occurred. Na3SiH7 is a new representative of yet elusive hydridosilicate compounds. Its double salt nature and polymorphism are strongly reminiscent of fluorosilicates and germanates.
Comparison of procedural characteristics of percutaneous annuloplasty and edge-to-edge repair for the treatment of severe tricuspid regurgitation
Authors: Mattig Isabel , Barbieri Fabian , Kasner Mario , Romero Dorta Elena , Heinrich-Schüler Anna Lisa , Zhu Miry , Stangl Karl , Landmesser Ulf , Reinthaler Markus , Dreger Henryk 
Published: September 2023

BackgroundIn recent years, new interventional therapies for tricuspid regurgitation (TR) demonstrated their effectiveness in reducing TR severity and improving symptoms. Currently, tricuspid transcatheter edge-to-edge repair (T-TEER) and percutaneous annuloplasty are the most widely used techniques in Europe. In this retrospective study, we compared procedural characteristics and learning curves of both TR devices in a real-world cohort.Material and methodsEligible patients with severe to torrential TR underwent either percutaneous annuloplasty or T-TEER as recommended by the local heart team. Patients with combined mitral and tricuspid interventions were excluded from the analysis. The study focused on procedural characteristics, TR reduction and learning curves.ResultsA total of 122 patients underwent either percutaneous annuloplasty (n = 64) or T-TEER (n = 58) with a technical and device success rate of 98% and 97%, respectively. Reasons for technical failure included right coronary artery (RCA) dissection prior to percutaneous annuloplasty, and two single leaflet device attachments (SLDA) during T-TEER implantation. The mean improvement of TR severity was 2.4 ± 0.8 degrees after T-TEER and 2.5 ± 0.8 after percutaneous annuloplasty. T-TEER procedures were shorter in terms of both procedure time and radiation exposure, while percutaneous annuloplasty, although taking longer, showed a significant reduction in procedure time over the course of the analysed period.ConclusionIn summary, both interventional therapies reduce TR severity by approximately two degrees when used in the appropriate anatomy. The learning curve for annuloplasty group showed a significant decrease of procedure times.
A single 36-h water-only fast vastly remodels the plasma lipidome
Authors: Hong Brian V. , Rhodes Christopher H. , Agus Joanne K. , Tang Xinyu , Zhu Chenghao , Zheng Jack Jingyuan , Zivkovic Angela M. 
Published: September 2023

BackgroundProlonged fasting, characterized by restricting caloric intake for 24 h or more, has garnered attention as a nutritional approach to improve lifespan and support healthy aging. Previous research from our group showed that a single bout of 36-h water-only fasting in humans resulted in a distinct metabolomic signature in plasma and increased levels of bioactive metabolites, which improved macrophage function and lifespan in C. elegans.ObjectiveThis secondary outcome analysis aimed to investigate changes in the plasma lipidome associated with prolonged fasting and explore any potential links with markers of cardiometabolic health and aging.MethodWe conducted a controlled pilot study with 20 male and female participants (mean age, 27.5 ± 4.4 years; mean BMI, 24.3 ± 3.1 kg/m2) in four metabolic states: (1) overnight fasted (baseline), (2) 2-h postprandial fed state (fed), (3) 36-h fasted state (fasted), and (4) 2-h postprandial refed state 12 h after the 36-h fast (refed). Plasma lipidomic profiles were analyzed using liquid chromatography and electrospray ionization mass spectrometry.ResultsSeveral lipid classes, including lysophosphatidylcholine (LPC), lysophosphatidylethanolamine (LPE), phosphatidylethanolamine, and triacylglycerol were significantly reduced in the 36-h fasted state, while free fatty acids, ceramides, and sphingomyelin were significantly increased compared to overnight fast and fed states (P &lt; 0.05). After correction for multiple testing, 245 out of 832 lipid species were significantly altered in the fasted state compared to baseline (P &lt; 0.05). Random forest models revealed that several lipid species, such as LPE(18:1), LPC(18:2), and FFA(20:1) were important features in discriminating the fasted state from both the overnight fasted and postprandial state.ConclusionOur findings indicate that prolonged fasting vastly remodels the plasma lipidome and markedly alters the concentrations of several lipid species, which may be sensitive biomarkers of prolonged fasting. These changes in lipid metabolism during prolonged fasting have important implications for the management of cardiometabolic health and healthy aging, and warrant further exploration and validation in larger cohorts and different population groups.
Landslide susceptibility mapping of Al Taif urban area, Saudi Arabia, using remote sensing data and microtremor measurements: integrated approach
Authors: Abdelrahman Kamal , Al-Amri Abdullah M. , Al-Kahtany Khaled , Al-Otaibi Naif 
Published: September 2023

Many people are killed by landslides due to earthquakes or severe rain, and structures and facilities built on or near slopes sustain significant damage. Such landslides on naturally occurring slopes can be large enough to utterly destroy towns or communities. Based on remote sensing and microtremor data, the area around Al Taif has been evaluated for its susceptibility to landslides. Digital elevation model (DEM), slope angle, and slope aspect thematic layers were used to depict remote sensing data. The landslide susceptibility was extracted from remote sensing thematic data. The elevations of the Al Taif area, which range from 832 to 2,594 m amsl, were identified based on the DEM. Al Taif’s slope angles range from 0° to 67.3° degrees. Nearly flat (0° to 4.75°), moderate (4.75° to 11.1°), steep (11.2° to 29.1°), and very steep slope (≤29.1°) are the different classifications for the slope. Additionally, measurements of the microtremor have been taken at 42 locations throughout the region. The horizontal-to-vertical spectral ratio (HVSR) approach was used to process and analyze microtremor data in order to determine the resonance frequency and H/V amplification factor. The findings show that, while the amplification factor varies from 1.17 to 9.28, the dominant frequency values fall between 0.3 and 12.75 Hz. To determine the frequency, amplitude, and azimuthal site response, 11 sites were eventually chosen. Furthermore, the direction of the site response in the sliding areas was parallel to the landslide directional response, indicating that the site response direction tracked the landslide direction. Practical approval of the study’s findings has been given at a number of locations by field measurements at some of the Taif urban area’s most recent landslide occurrence areas. These findings show that the integration between remote sensing and microtremor measurements is a useful tool for pinpointing landslide-prone areas, which helps to lessen the danger to people’s lives and property. This susceptibility zonation applied to the Al Taif area has produced a good match between the distribution of the reported landslides and the zones of high susceptibility. To define the general trend and geographic distribution of potentially unstable slopes and landslide potential zones, this study’s findings must be used as a guide.
Superheating field in superconductors with nanostructured surfaces
Authors: Pathirana W. P. M. R. , Gurevich A. 
Published: September 2023

We report calculations of a DC superheating field Hsh in superconductors with nanostructured surfaces. Numerical simulations of the Ginzburg–Landau (GL) equations were performed for a superconductor with an inhomogeneous impurity concentration, a thin superconducting layer on top of another superconductor, and superconductor–insulator–superconductor (S-I-S) multilayers. The superheating field was calculated taking into account the instability of the Meissner state with a non-zero wavelength along the surface, which is essential for the realistic values of the GL parameter κ. Simulations were performed for the material parameters of Nb and Nb3Sn at different values of κ and the mean free paths. We show that the impurity concentration profile at the surface and thicknesses of S-I-S multilayers can be optimized to enhance Hsh above the bulk superheating fields of both Nb and Nb3Sn. For example, an S-I-S structure with a 90-nm-thick Nb3Sn layer on Nb can boost the superheating field up to ≈500 mT, while protecting the superconducting radio-frequency (SRF) cavity from dendritic thermomagnetic avalanches caused by local penetration of vortices.
Case report: Remarkable response to a novel combination of mitotane, etoposide, paraplatin, and sintilimab in a patient with metastatic adrenocortical carcinoma
Authors: Weng Yan , Wang Lin , Wang Xiao-Yi , Fan Xin-Xiang , Yan Li , Li Zhi-Hua , Zhang Shao-Ling 
Published: September 2023

BackgroundAdrenocortical carcinoma (ACC) is a rare malignancy with a poor prognosis and limited treatment options for metastases. However, new effective regimens are emerging for specific conditions in metastatic ACC.Case presentationWe report a case of a 36-year-old man diagnosed with metastatic ACC who had a large left adrenal mass (158 mm × 112 mm) and multiple metastases in the liver and lungs. Genetic testing revealed a microsatellite instability-high (MSI-H) tumor, a splice mutation in MLH1, and a high tumor mutational burden (TMB). After the left adrenalectomy, he received sequential treatment with a combination of mitotane, etoposide, paraplatin (EP-M), and sintilimab. His condition has been assessed as a stable disease since the sixth cycle of the combined regimen.ConclusionThis case highlights the remarkable response of our patient’s ACC with MSI-H tumor, MLH1 spice mutation, and high TMB to treatment with a novel combination of EP-M and sintilimab. Our findings suggest a promising therapeutic option for patients with similar molecular profiles.