bluuebunny/crossref_metadata_2025_split huggingface dataset:
Experimental data and Modeling of Solid-Liquid Equilibria of Binary Systems Containing Dibenzofuran and Long Chain n-alkanes
Authors: Boudouh Issam , Coto Baudilio , González Juan Antonio , Wazeer Irfan , Salleh M. Zulhaziman M. , Djemai Ismahane , Robustillo Maria Dolores , Hadj-Kali Mohamed K. 
Published: January 2023

Abstract

Solid-liquid equilibria (SLE) of binary mixtures of several n-alkanes (n-octadecane, n-eicosane, n-tetracosane, n-pentacosane, n-triacontane) and dibenzofuran covering the whole composition range were measured by differential scanning calorimetry (DSC) in a temperature range of 301-356 K. The dibenzofuran and the n-alkanes are completely miscible in the liquid state but non-miscible in the solid-state, and in the context of this work, they seem to exhibit eutectic behavior. A linear trend is obtained for the eutectic temperature and eutectic composition versus the number of carbon atoms of n-alkane. The experimental data were compared to predictions made by using the ideal solution model, the DISQUAC model and several versions of the UNIFAC model, including the classical UNIFAC, the modified versions of Lyngby and Dortmund, and the recently proposed modified UNIFAC (NIST) model, to account for non-ideality in the liquid phase. Moreover, the experimental data were also compared with COSMO-RS predictions that utilize quantum chemical calculations and statistical thermodynamics to interpret the behavior of molecular interactions in the binary mixture. A good agreement was obtained between the predicted and the experimental temperatures.
The delayed fracture test for viscoelastic elastomers
Authors: Lopez-Pamies Oscar , Shrimali Bhavesh 
Published: January 2023

Abstract
In a recent contribution, Shrimali and Lopez-Pamies (2023) have shown that the Griffith criticality condition that governs crack growth in viscoelastic elastomers can be reduced — from its ordinary form involving a historically elusive loadinghistory-dependent critical tearing energy Tc — to a fundamental form that involves exclusively the intrinsic fracture energy Gc of the elastomer. The purpose of this paper is to make use of this fundamental form to explain one of the most distinctive fracture tests for viscoelastic elastomers, the so-called delayed fracture test.
Synergistic toxicity against housefly Musca domestica of plant essential oils and their major constituents and safety against a non-target pollinator
Authors: Moungthipmalai Tanapoom , Puwanard Cheepchanok , Sittichok Sirawut , Soonwera Mayura 
Published: January 2023

Abstract

Plant essential oils (EOs) can fulfill the role of safe and effective fly repellent and adulticide. Individual and binary mixture formulations of Cymbopogon citratus (Stapf.) and Illicium verum (J. Presl.) EOs and their major constituents were assayed for their repellent and adulticidal activities against Musca domestica L. and non-target pollinator, Apis florea F. Their efficacy was compared to that of 1.0% (w/v) α-cypermethrin. A GC-MS analysis found that geranial and trans-anethole were the major constituents of C. citratus EO (45.23%) and I. verum (93.23%), respectively. All binary mixture formulations exhibited high and synergistic repellent and adulticidal effects: an increased repellent value between 18.7 to 57.6%, and a mortality rate value between 41.9 to 92.7%. The highest synergistic repellent effect was from 2.5% C. citratus EO + 2.5% I. verum EO, while the highest synergistic adulticidal effect was from 1.0% C. citratus EO + 1.0% trans-anethole. Both were more effective than 1.0% (w/v) α-cypermethrin. On the other hand, they were not toxic to the non-target pollinator. To conclude, C. citratus EO + I. verum EO and C. citratus EO + trans-anethole have a high potential as repellent and adulticidal agents against M. domestica which are safe for a pollinator, Apis florea.
Influence of Vortex Finder Dimensions in a Circumfluent Cyclone: CFD-DPM Simulation
Authors: Ortiz Jose Alfredo Paredes , Quinayá Diana Carolina Parada 
Published: January 2023

Abstract
As part of the production process, a large amount of fine particles is generated in various industries, so it is necessary to find new technologies to improve the separation of solid gases. This study investigated a Circumfluent cyclone model for the efficient separation of fine particles. The influence of the extension of the Vortex Finder or separation column on the particle trajectories was evaluated, 3 Vortex Finder diameters were compared and it was determined for the case study the optimum diameter for particle separation is set at 160 mm.
Mass Media Exposure and Health Insurance: The Moderating Role of Education and Wealth among Community-dwelling Older Adults from the Longitudinal Aging Study in India
Authors: Barman Papai , Karmakar Ranjan , Roy Alok , Dakua Manoj 
Published: January 2023

Abstract
This study aimed to examine the association of mass media exposure (MME) with enrolment in health insurance (HI) and its moderating effect on the associations among older adults in India. The data of 29,935 older adults aged 60 + were used from the Longitudinal Ageing Study in India (LASI-2017-18). Descriptive statistics, bivariate analysis, moderated multivariable logistic regression models, and Fairlie decomposition were all used to achieve the objectives of the research. The results showed that enrolment in HI and MME among older individuals in India was at about 18.3% and 43.5%, respectively. Older adults who had MME, one or more years of schooling, and non-poor consumption expenditure (MPCE) were 1.39 times [adjusted odd ratio (aOR): 1.39, CI: 1.30–1.49], 1.23 times [aOR: 1.23, CI: 1.15–1.32] more likely, and 0.88 times [aOR: 1.39, CI: 1.30–1.49] more likely to be enrolled in health insurance than those with no MME, no schooling, and poor MPCE, respectively. Additionally, MME increases the likelihood of enrolment in HI and modifies associations between schooling, MPCE, and enrolment in HI. The study's conclusions imply that it would be wise to consider the use of these communication channels when developing strategic communication plans to promote HI enrolment in India.
Sex differences in brain atrophy in dementia with Lewy bodies
Authors: Oltra Javier , Habich Annegret , Schwarz Christopher G. , Nedelska Zuzana , Przybelski Scott A. , Inguanzo Anna , Diaz-Galvan Patricia , Lowe Val J. , Oppedal Ketil , Blanc‬ ‪Frederic , Lemstra Afina W. , Hort Jakub , Padovani Alessandro , Rektorova Irena , Bonanni Laura , Massa Federico , Kramberger Milica G. , Taylor John-Paul , Snædal Jon , Walker Zuzana , Antonini Angelo , Segura Barbara , Junque Carme , Westman Eric , Boeve Bradley F. , Aarsland Dag , Kantarci Kejal , Ferreira Daniel 
Published: January 2023

Abstract

Background and objectives.
Sex is an important contributing factor to neuroimaging phenotypes in brain disorders. However, little is known about the contribution of sex differences to the neurodegeneration in dementia with Lewy bodies (DLB). We investigated sex differences in probable DLB patients by using both visual rating scales of lobar atrophy and automated estimations of regional atrophy.
Methods.
We included 442 probable DLB patients from the European-DLB consortium and the Mayo Clinic who have magnetic resonance imaging (MRI) data available. We assessed sex differences and the sex-by-age interaction in two largely independent samples through visual rating scales of lobar atrophy (n = 333; mean age 73 ± 8 years, 62% males) and automated regional estimations of gray matter (GM) volume and mean cortical thickness (CTh) (n = 165; mean age 69 ± 9 years, 72% males). We used binary logistic regression and ANOVA for statistical analysis.
Results.
We found a statistically significantly higher likelihood of frontal atrophy measured by the global cortical atrophy-frontal subscale (GCA-F) in males (40% of males had an abnormal GCA-F score versus 29% of females, P-value = 0.006). Using automated estimations, we found smaller GM volumes in 6 cortical regions in males compared with females, as well as smaller GM volume in the entorhinal cortex and thinner olfactory cortices in females, compared with males. The sex-by-age interaction showed statistically significant results in 6 cortical volumes and 7 mean CTh estimations (P-value ≤ 0.05), accentuated in the right middle frontal gyrus (FDR-adjusted P-value = 0.047). These cross-sectional interactions indicated that while females have statistically significantly less atrophy than males at younger ages, differences become non-significant at older ages, with females showing the same level of atrophy than males around the age of 75.
Conclusions.
This study demonstrates sex differences on brain atrophy in probable DLB. While male DLB patients have a more widespread pattern of cortical atrophy at younger ages, these sex differences tend to disappear with increasing age. Longitudinal studies will help establish these cross-sectional findings and inform on sex and age considerations to the use of MRI in clinical routine, as the field moves towards precision medicine.
Biofuel Production from Sensitive Plant (Mimosa Pudica) through Synchronized Biofuel Production Plant
Authors: Adewumi Idowu Olugbenga 
Published: January 2023

Abstract

Mimosa pudicais among the medicinal herbal plant. It is a creeping annual or perennial herb often grown for its curiosity values; as the compound leaves fold inward and drop when touched and reopens within minutes later. It belongs to Fabaceae family. The general objective of these research work is to produce biofuel from sensitive plant using existing ethanol production plant. The sensitive plant was gotten from bushes at Moor Plantation, samples as used include 78% concentration of Hydrogen tetraoxosulphate (iv) acid (H2SO4), 3L, 6L and 9L of water was added with the mass of sensitive plant. The evaluation was carried out using the mass of dried sensitive plant (Mimosa pudica) such as replicate mass of sensitive plant (kg), volume of H2SO4 (L), volume of H2O (L) added to ferment the feed stock, mass of ethanol produced after been distilled (kg), volume of ethanol produced (L), time and temperature used from each ethanol extraction. Also, it was observed that the average quantity of mean of mass of ethanol produced after been distilled from 0.5kg of sensitive plant (Mimosa pudica) to be 0.0404kg, average quantity of mean of volume of ethanol produced is 0.0454 L and the average quantity of mean of temperature is 74.680C. It was concluded that the temperature of the ethanol produced increases as the mass of sensitive plant increases and its time of production of each replicate (0.5kg, 1.0kg, 1.5kg) also increases.
The Teaching of Writing in EFL Classes
Authors: Srikandi  
Published: January 2023

Writing plays important roles in the context of English teaching as a foreign language in Indonesia. Writing is a communicative way of sharing observation, information, thoughts, or ideas with ourselves and others. Through writing, the language learners learn to communicate with other people, to understand them, to read what they have written, and to write to them. Writing as one of the language skills is not acquired naturally. Writing is considered the most difficult and complicated language skill to be learned compared to other language skills. Learning to write fluently and expressively is the most difficult of four language skills for all students. In the teaching of writing, the English teacher should pay attention on some elements, they are: (1) understanding the purposes of teaching writing, (2) teaching five main stages in producing a writing; pre-writing, drafting, revising, editing and publishing, (3) teaching how to develop a paragraph which consists of three major structural parts: a topic sentence, supporting sentences, and concluding sentence, (4) employing appropriate techniques, such as brainstorming, quetioning, and clustering in their teaching, and (5) introducing some text type to the students, such as: narration, description, procedure, news item, report, recount, anecdote, hortatory exposition, analytical exposition, commentary, discussion, and explanation.
HATAY’DAN ORTADOĞU ÜLKELERİNE GİDEN İŞÇİLER ÜZERİNE BİR DEĞERLENDİRME
Authors: KOLUTEK Mikail , SAVAŞGÜR Ahmet Vedat 
Published: January 2023

Hatay, Orta Doğu ülkelerine yönelen iş gücü göçünün yoğun olarak gerçekleştiği Türk şehirleri arasında özel bir yere sahiptir. 1973 yılı sonu itibariyle Türk işçiler, Orta Doğu ülkelerine kitleler halinde yönelirken, Hatay kenti, ülkenin önemli iş gücü ihracatçılarından biri olma konumuna gelmiştir. Hatay ilinden Orta Doğu bölgesine yönelen ve dinamik bir yapı arz eden göç örgüsünün tarihsel süreç içerisinde nasıl gerçekleştiği önem arz etmektedir. Orta Doğu’ya giden işçilerin ekonomik kazançları ile bu kazançların işçilerin ömrü boyunca sürecek zenginleşmeye yol açıp-açmadığı bilinmemektedir. Bölgeden yaşanan göçlerin Hatay’ın iktisadi durumu ve istihdam yapısı üzerine olan etkileri önemli bir husustur. Yaşanan iş gücü göçlerinde Hataylı işçilerin neden Orta Doğu ülkelerini tercih ettiği ise somut olarak açıklanmalıdır. Ayrıca Orta Doğu ülkelerine giden Hataylı işçilerin yapısal analizi, kaynak ve hedef bölgeler arasında kurulan göç organizasyonu da izahının yapılması gereken bir diğer konudur.
Hatay’dan Orta Doğu ülkelerine 1967-2020 yılları arasında yapılan iş gücü göçlerinin irdelendiği bu çalışmada konu çok yönlü olarak ele alınmıştır. Hatay ili genelinde kartopu örnekleme yöntemiyle uygulanan anketle nicel veriler toplanarak, yarı yapılandırılmış görüşmeler aracılığıyla da nitel veriler elde edilmiştir. Araştırma verileri, Hatay’dan Orta Doğu ülkelerine yönelen göçün tarihsel süreci, bölgeye giden işçilerin yapısal analizi, göç organizasyonu ve iktisadi kazancın değerlendirilmesi noktasında birçok tespit yapılmasına imkân tanımıştır. Hatay’dan gerçekleşen iş gücü göçünün şehir ve işçiler üzerinde iktisadi ve sosyal kazanımları olduğu tespit edilmiştir.
Hydrogen Sulfide (H2S): As a Potent Modulator and Therapeutic Prodrug
in Cancer
Authors: Faris Pawan , Negri Sharon , Faris Delia , Scolari Francesca , Montagna Daniela , Moccia Francesco 
Published: January 2023

Abstract:
Hydrogen sulfide (H2S) is an endogenous gaseous molecule present in all living
organisms that has been traditionally studied for its toxicity. Interestingly, increased
understanding of H2S effects in organ physiology has recently shown its relevance as a
signalling molecule, with potentially important implications in variety of clinical disorders,
including cancer. H2S is primarily produced in mammalian cells under various enzymatic
pathways are target of intense research biological mechanisms, and therapeutic effects
of H2S. Herein, we describe the physiological and biochemical properties of H2S,
the enzymatic pathways leading to its endogenous production and its catabolic routes. In
addition, we discuss the role of currently known H2S-releasing agents, or H2S donors, including
their potential as therapeutic tools. Then we illustrate the mechanisms known to
support the pleiotropic effects of H2S, with a particular focus on persulfhydration, which
plays a key role in H2S-mediating signalling pathways. We then address the paradoxical
role played by H2S in tumour biology and discuss the potential of exploiting H2S levels
as novel cancer biomarkers and diagnostic tools. Finally, we describe the most recent preclinical
applications focused on assessing the anti-cancer impact of most common H2S-releasing
compounds. While the evidence in favour of H2S as an alternative cancer therapy
in the field of translational medicine is yet to be clearly provided, application of H2S is
emerging as a potent anticancer therapy in preclinical trails.
Contemporary Progress in the Applications of Iron-based Magnetic Nanoparticles in
Multicomponent Synthesis: A Review
Authors: Srivastava Neelanjana , Verma Monika , Thakur Ajay , Bharti Ruchi , Sharma Renu 
Published: January 2023

Abstract:
In recent decades, organic synthetic reactions have advanced towards a greener and sustainable reactions by the usage of magnetic nanoparticles (MNPs). Such nanoparticles can be quickly recovered and reused in various organic syntheses. MNPs are a sustainable methodology while encountering environmental and profitable advantage. Due to their properties, MNPs have broad impacts on multiple fields. For instance, their size and magnetic properties have significant implications for various biomedicine, environmental remediation projects, and catalysis. MNPs are an alternative to conventional materials. These are smaller and have a high surface area that allows them to have copious catalytic sites. Amongst various MNPs, iron-based nanoparticles are being profoundly explored in different multicomponent reactions (MCRs). A convergent reaction, which retains most of the significant atoms of the starting components. This investigation targets to equip its readers a brief appertaining to nanoparticles, their processing, and characterization and summarize the evolution in applications of Iron-based MNPs in multicomponent synthetic procedures since 2010.
Use of Lithium in Pediatric Bipolar Disorders and Externalizing Childhood-
related Disorders: A Systematic Review of Randomized Controlled
Trials
Authors: Janiri Delfina , Moccia Lorenzo , Montanari Silvia , Zani Valentina , Prinari Claudia , Monti Laura , Chieffo Daniela , Mazza Marianna , Simonetti Alessio , Kotzalidis Georgios D. , Janiri Luigi 
Published: January 2023

Background:
Lithium is the standard treatment for bipolar disorders (BD) in adults. There
is a dearth of data on its use in the pediatric age. This review aimed to investigate the use of lithium in
pediatric bipolar disorder (BD) and other externalizing childhood-related disorders.

Methods:
We applied the Preferred Reporting Items for Systematic Reviews and Meta-analyses criteria
(PRISMA) to identify randomized controlled trials evaluating the use of lithium in pediatric (BD),
conduct disorder (CD), attention deficit hyperactivity disorder, oppositional defiant disorder, and disruptive
mood dysregulation disorder. The primary outcome of our study was to evaluate the efficacy
of lithium compared to a placebo or other pharmacological agents. The secondary outcomes were acceptability
and tolerability.

Results:
Twelve studies were eligible, 8 on BD and 4 on CD. Overall, 857 patients were treated with
lithium. No studies for externalizing disorder diagnoses were identified. Regarding BD patients
(n = 673), efficacy results suggested that lithium was superior to placebo in manic/mixed episodes but
inferior to antipsychotics. Lithium efficacy ranged from 32% to 82.4%. Results on maintenance need
to be expanded. Comorbidity rates with other externalizing disorders were extremely high, up to
98.6%. Results in CD patients (n= 184) suggested the efficacy of lithium, especially for aggressive behaviors.
No severe adverse events directly related to lithium were reported in BD and CD; common
side effects were similar to adults.

Conclusions:
This systematic review supports the use of lithium in BD and CD as an efficacious and
generally well‐tolerated treatment in the pediatric age. However, evidence is limited due to the paucity
of available data.
QbD Assisted Development and Validation of UV Spectroscopic Method in
Estimation of Silymarin
Authors: Mishra Ashwini Kumar , Neha S.L. , Rani Laxmi , Dewangan Hitesh Kumar , Sahoo Pravat Kumar 
Published: January 2023

Background:
Silymarin is a flavonoid utilised in liver dysfunction for years; new studies have
emphasised its potential utility as a therapy for nanoparticulate targeting in many other disorders. In order
to establish the product quality of such compounds, researchers have been trying to develop a robust
method of analysis, but the methods developed till now are too expensive and time-consuming. Here we
proposed quality by design-assisted development and validation of the UV spectroscopic method using
Design-Expert® software in the estimation of Silymarin for fabrication of nanoparticulate formulations,
which is simple, accurate, cost-effective and non-tedious.

Aim:
The proposed method is a simple, new, robust, accurate, and precise UV visible spectroscopic
technique for estimating silymarin produced in nano-formulations utilising an analytical quality by design
(AQbD) approach.

Methods:
A UV spectrophotometric technique was established, as maximum absorption (287.7) was
measured using a Shimadzu UV-1800 double-beam UV visible spectrophotometer. The characterization
of silymarin was done by melting point, DSC and FTIR techniques. The two critical method variables
chosen were scanning speed and sample interval to be analysed by the design of experiment methodology
utilizing the central composite design principle, which shows robustness and optimized technique involved
in this work.

Results:
The spectroscopy technique was developed and validated as per International Conference of
Harmonization recommendations. The Beer's-Lambert rule was followed in a series of 2-12 μg/ml dilution
increments, with a correlation value of R2 = 0.999. The method's linearity was shown to be excellent
across the concentration range. The percent recovery of the current method approach was determined to
be within the confidential limitations, i.e., less than 2% expressed as % RSD, and the methodology was
proved to be precise at inter and intraday variations (% RSD). The LOD and LOQ were found to be 0.264
μg/ml and 0.801 μg/ml which were also determined correctly. During specificity testing, no interfering
peaks were found.

Conclusion:
This UV approach has been used successfully to determine the quantity of silymarin present
in the nanoparticulate formulation, which can be used for testing its other pharmaceutical dosage forms.
Hydrogel-based Treatment Strategies to Accelerate Diabetic Foot Ulcer Healing
Authors: Mehta Sadgi , Wadhwa Sheetu , Nayak Sammisla R. , Kumar Rajesh 
Published: January 2023

Abstract:A diabetic foot ulcer is a chronic clinical manifestation of diabetes that exacerbates the condition of a patient and has a considerable socioeconomic impact. A diabetic foot ulcer (DFU) impacts around 25% of patients with diabetes mellitus at a certain point in their lives, and the underlying cause of the condition appears to be linked to neuropathic, ischaemic, and/or neuroischaemic pathologies. For the effective treatment of DFU, a variety of conventional treatments are used. However, in recent years, a range of innovative materials have been studied to bolster standard treatment tactics and promote the desired biological response by transcending the impediments of current wound healing approaches. Inorganic/organic hydrogel hybrids for tissue regeneration are among the most promising materials. This review article outlines the current treatment options for DFU, applications of hydrogel with an emphasis on wound healing, polymeric materials used to fabricate hydrogel, and the role of emerging technologies.