bluuebunny/crossref_metadata_2025_split huggingface dataset:
Monetary stance and favorableness of the monetary policy in the media: the case of Vietnam
Authors: Doan Thang Ngoc , Do Dong Phu , Luong Dat Van 
Published: August 2023

PurposeThis paper analyzes the effects of the monetary stance on the media's favorable (or otherwise) attitude to the State Bank of Vietnam's (SBV) monetary policy using monthly data from 2011 to 2021. Monetary stance is a multivariate index based on the growth rates of money supply and domestic credit. A large set of articles published in five Vietnam daily newspapers are utilized to construct a view of the media's favorableness to the monetary policy.Design/methodology/approachThis paper uses hand-collected data from 211 articles published in five newspapers from December 2011 to September 2021 in order to examine the relationship between the monetary stance and the media's favorableness to monetary policy. Following the studies of He and Pauwels (2008) and Xiong (2012), the authors constructed a multivariate stance index to capture most of the important changes in the SBV's monetary policy stance.FindingsThe study's main findings are that a change in monetary stance from easing to neutral/tightening, or from neutral to tightening, is greatly appreciated by the media. The study's findings are robust, especially in terms of alternative measures of the media's favorableness and monetary policy variables.Research limitations/implicationsThese findings have important policy implications for implementing SBV's monetary policy.Originality/valueThe main contribution of this paper is that the authors are the first to study the nexus of multivariate monetary stance and the media's favorableness to a central bank's non-inflation-targeting mandate. In particular, the study’s findings confirm that the SBV's multivariate monetary stance affects the media's favorableness, whereas the effect of inflation is statistically insignificant.
Artificial intelligence in healthcare: the value co-creation process and influence of other digital health transformations
Authors: Swan Eric L. , Peltier James W. , Dahl Andrew J. 
Published: August 2023

PurposeDigital transformations are altering service models and care delivery methods in healthcare. Artificial Intelligence (AI) represents the next wave of transformation in healthcare. This study aims to understand patient perceptions of AI and its impact on value co-creation.Design/methodology/approachA conceptual model was developed to investigate how value co-creation operant resources (digital self-efficacy and relational service quality) impact value co-creation engagement (shared decision-making) and value co-creation outcomes (anticipatory AI value co-creation and intention to adopt AI). Data were collected from 332 respondents and analyzed using structural equation modeling.FindingsThe results indicate that the value co-creation process for AI technologies is a function of inputs, experiences and AI outputs. Operant resources were found to be positively associated with shared decision-making. However, not all operant resources directly and positively impacted AI outcomes. The indirect and positive mediated relationships through shared decision-making to AI outcomes suggest an interactive AI value co-creation process.Research limitations/implicationsAI technologies are still in early stages of consumer adoption in healthcare. Future research is warranted that investigates the validity of the model through maturing service life cycles.Practical implicationsCustomer perceptions of new digital innovations are formed in the context of previous digital experiences. Marketers need to understand how customers view their current non-AI technologies. Strong engagement and perceived value of current technologies will help ease customers into the usage of AI technologies.Originality/valueThis study investigates the unique stages of the value co-creation process for AI technologies in healthcare. The results demonstrate that the value co-creation process is a function of inputs, tech-enabled experiences and AI outputs.
Does adaptability, rurality and previous business ownership matter for entrepreneurial identity?
Authors: Barber III Dennis , Lawrence Ericka R. , Alipour Kent , McMillan Amy 
Published: August 2023

PurposeThis study explores the role of both trait-like (i.e. adaptability) and situational (previous small business ownership and rurality) variables, on entrepreneurial identity (EI) through a social identity theory lens.Design/methodology/approachPath analysis was used on 376 individuals from across the United States who met various criteria and were recruited using Prolific.FindingsAdaptability and previous small business ownership were found to be predictors of EI. Findings also highlight the moderating role of adaptability on the previous small business ownership-EI and rurality-EI links. Notably, highly adaptable individuals who have previously owned businesses tend to hold more of an EI, and those who are less adaptable and live in rural locations also tend to hold less of an EI.Practical implicationsUnderstanding the conditions under which individuals are likely to hold more of an EI may provide several benefits to organizations and individuals within society, including information that can be used to develop more fine-tuned career counseling and training, risk management strategies, and a more calculated allocation of finite resources.Originality/valueDespite both personal trait-like (i.e. focus/adaptability) and situational (i.e. rurality and previous small business ownership experience) factors likely playing a crucial role in the formation of individuals' perceptions, previous work has largely ignored their interaction in the development of EI. The authors test a model encompassing trait-like (i.e. focus/adaptability) and situational (rurality, previous small business ownership experience) predictors of EI, along with their interactive effects, and illuminate a more holistic picture of EI's antecedents.
An exploratory study of the future paranormal tourist experience on ghost tours
Authors: Pedreño-Peñalver Carmen , Huertas-Valdivia Irene , Orea-Giner Alicia 
Published: August 2023

Purpose The purpose of this study is to explore the paranormal tourist experience on ghost tours, taking into account the participants’ perceptions and their prior knowledge of the paranormal, in order to determine the principal components of the future of paranormal tourist experience.Design/methodology/approach The study is divided into two phases. The first phase is based on participant observation during a ghost tour. The second phase is based on a previously published framework for paranormal tourism. It introduces a qualitative adaptation of the orchestra model to look in-depth at how experiences with paranormal tours might shape the future of tourism as a major subtype.Findings Paranormal tourism has external (situational-enchantment, historical, mystical, ghostly and unsolved mysteries) and internal (affective, cognitive, sensory, behavior and relationship) components that are inter-linked. Future paranormal tourist experiences (FPTEs) must be focused on enhancing these aspects in order to offer an immersive experience.Originality/valueConsequently, this paper proposes the FPTE model.
The causal effect of political risk on the stock market: Evidence from a natural experiment
Authors: Li Zhibing , Liu Jia , Liu Jie , Liu Xiaoyu , Zhu Yinglun 
Published: August 2023

AbstractBy using the misfired missile event from Taiwan to mainland China as an exogenous shock, we identify the causal effect of potential military risk on the Chinese A‐share market. We find that the misfired missile event indeed causes a significant decline in the stock prices of Taiwan‐related A‐share firms, especially for firms that have stronger relationship with Taiwan. Further analysis shows that the increased required rate of return due to higher political uncertainty is the main driving force of the stock price decline. Our findings provide strong support for the existence of priced political risk in the stock market.
Comprehensive assessment of pretreatment sarcopenia impacts on patients with EGFR‐mutated NSCLC treated with afatinib
Authors: Wu Chen‐Te , Hsu Ping‐Chih , Chang John Wen‐Cheng , Chang Ching‐Fu , Huang Chen‐Yang , Yang Cheng‐Ta , Kuo Chih‐Hsi Scott , Fang Yueh‐Fu , Wu Chiao‐En 
Published: August 2023

AbstractBackgroundThis study aimed to comprehensively evaluate the efficacy and toxicity of afatinib in patients with sarcopenia, an important prognostic factor for treatment efficacy and toxicity in patients with cancer.MethodsThe clinical features of patients with advanced NSCLC treated with frontline afatinib between 2014 and 2018 at a medical center in Taiwan were retrospectively reviewed. Sarcopenia was evaluated based on the total cross‐sectional area of skeletal muscles assessed by computed tomography (CT) imaging at the L3 level. Baseline characteristics, response rates, survival rates, and adverse events (AEs) were compared between sarcopenic and nonsarcopenic patients.ResultsA total of 176 patients evaluated for sarcopenia by CT and treated with afatinib were enrolled in the current study. Sarcopenia was significantly associated with good performance status, low body mass index (BMI), low body surface area (BSA), and low total mass area (TMA). Sarcopenia did not influence the response rate (69.2% vs. 72.0%, p = 0.299), progression‐free survival (median 15.9 vs. 14.9 months, p = 0.791), or overall survival (median 26.5 vs. 27.2 months, p = 0.441). However, BSA ≤ 1.7 and the 40 mg afatinib dose were associated with dose reduction. TMA was the only independent factor for afatinib discontinuation due to AEs.ConclusionSarcopenia was not associated with treatment efficacy or toxicity among patients with NSCLC harboring common mutations treated with afatinib, indicating sarcopenic patients should not be excluded from afatinib treatment. Other factors, such as BSA and TMA, were associated with dose reduction and afatinib discontinuation, respectively, which may require additional evaluations in future studies.
The impact of board ethnic diversity and Chief Executive Officer role on corporate social responsibility
Authors: Do Truc (Peter) , Herbohn Kathleen 
Published: August 2023

AbstractWe examine the influence of board ethnic diversity on firms' corporate social responsibility (CSR) activities within modern day corporations. Using firm‐year observations in Australia from the period 2004–2017, we document that board ethnic diversity leads to better CSR performance and CSR disclosure. Our results suggest that for every additional ethnic cluster represented on the board, on average, a firm's CSR performance rating from ASSET4 is higher by 2.6% and the odds ratio of producing a CSR report increases by 38.8%. The results are robust to controlling for endogeneity (using both instrumental variable approach and difference‐in‐differences analysis) and alternate proxies to measure CSR performance and ethnic diversity. We also document the moderating impact of Chief Executive Officer (CEO) power on the relationship between board ethnic diversity and firms' CSR activities. Specifically, a less powerful CEO and a CEO of ethnic minority (i.e., non‐Anglo) are more likely to facilitate this relationship. This study adds to our understanding of how board ethnic diversity, an often‐overlooked factor in prior research, can have significant impacts on firm outcomes.
‘Like every other day’: Writing temporalities of banal exploitation among precarious migrant workers
Authors: Yea Sallie 
Published: August 2023

AbstractThe violence of precarious labour migration is often represented in popular and policy accounts through episodic frames that emphasise particular—often sensationalised and extreme—aspects and moments of more complex and mundane experiences. These depictions commonly appear under the labels of ‘modern‐day slavery’ and ‘labour trafficking’. This paper advances a participatory methodology aimed at elucidating more complex temporalities experienced by precarious migrant labourers, drawing on a project with male migrant workers in Singapore. The methodology developed for this project centres on written diaries/narratives authored by the participants over periods ranging from one to three months. These detailed narratives document struggles—physically, relationally, financially and emotionally—in the context of post‐labour destitution. These struggles appear as both ‘everyday’ difficulties and longer‐term problems, with both temporalities rendered visible as a form of slow violence. This methodology fuses key principles of qualitative longitudinal research (QLR) methods with participatory action research (PAR) to develop a methodological orientation to temporally extenuative experiences of violence that are visible through processes that draw on participants as key producers of knowledge and advocates for change. As a way of engaging migrants' mundane post‐labour struggles, this methodology allows for tracing of the longer‐term and cumulative impacts of precarious migrant labour through participants' own frames of reference.
Unheard voices: The sexual challenges of families of patients with bipolar disorder: A qualitative content analysis
Authors: Yaghmaei Safura , Babamohamadi Hassan , Shamsaei Farshid , Ghods Ali Asghar 
Published: August 2023

AbstractObjectivesThe aim of this study was to explore the voices of the family members of Bipolar Disorder (BD) patients about the challenges ahead of them.MethodsIn this qualitative study, 22 participants shared their experiences of sexual challenges of patients with BD through in‐depth, face‐to‐face, semi‐structured interviews. Qualitative content analysis was used for data analysis.ResultsAn overarching theme entitled “Unheard voices” reflected this experience. It comprised four main categories include sexual promiscuity, a change in sexual patterns, sexual support, and sexual indifference. The results revealed that the families of patients with BD have to deal with sexual promiscuity and change in sexual patterns in their family, and the family system attempts to respond to these changes by sexual support mechanisms and sexual indifference.ConclusionsGiven the significant impact of healthy sexual behaviors on the quality of life of both the individual and the family, therapists and family support systems are advised to strengthen and educate families to support their patients' sexual health and needs and protect their sexual existence; they should also address the sexual challenges faced by these families as a diagnostic and therapeutic priority, and early sexual health interventions should be provided to these families.
Human phenotype caused by biallelic KDM4B frameshift variant
Authors: Takada Sanami , Silva Sebastián , Zamorano Ivonne , Pérez Andrea , Iwabuchi Chisato , Miyake Noriko 
Published: August 2023

AbstractKDM4B (MIM*609765, NM_015015.3, formerly JMJD2B) encodes a histone demethylase and regulates gene expression via demethylation, mainly of H3K9 tri‐methylation. Heterozygous KDM4B loss‐of‐function variants cause autosomal dominant intellectual developmental disorder 65 (MIM#619320), which is characterized by global developmental delay, intellectual disability, language and gross motor delays, structural brain anomalies, characteristic facial features, and clinodactyly. Although the majority of reported patients have de novo pathogenic variants, some patients inherit pathogenic variants from affected parents. To our knowledge, only 23 patients with heterozygous KDM4B variants have been reported to date, and there are no reports of patients with biallelic KDM4B pathogenic variants. Herein, we report a female patient with a biallelic KDM4B frameshift variant (NM_015015.3: c.1384_1394delinsGGG, p.(Leu462Glyfs*43)) located at exon 12 of 23 protein‐coding exons, which is thought to be subject to nonsense‐mediated mRNA decay and no protein production. She presented developmental and language delays and a hypotonic and characteristic face. The patient's phenotype was more obvious than that of her mother, who is heterozygous for the same variant. Although declining birth rate (embryonic lethality in male mice) in homozygous knockout mice has been demonstrated, our report suggests that homozygous KDM4B frameshift variants can be viable in humans at least female.
Learning curve for robotic‐assisted total mesorectal excision: a multicentre, prospective study
Authors: Arquillière J. , Dubois A. , Rullier E. , Rouanet P. , Denost Q. , Celerier B. , Pezet D. , Passot G. , Aboukassem A. , Colombo P. E. , Mourregot A. , Carrere S. , Vaudoyer D. , Gourgou S. , Gauthier L. , Cotte E. 
Published: August 2023

AbstractAimRobotic‐assisted surgery (RAS) is becoming increasingly important in colorectal surgery. Recognition of the short, safe learning curve (LC) could potentially improve implementation. We evaluated the extent and safety of the LC in robotic resection for rectal cancer.MethodConsecutive rectal cancer resections (January 2018 to February 2021) were prospectively included from three French centres, involving nine surgeons. LC analyses only included surgeons who had performed more than 25 robotic rectal cancer surgeries. The primary endpoint was operating time LC and the secondary endpoint conversion rate LC. Interphase comparisons included demographic and intraoperative data, operating time, conversion rate, pathological specimen features and postoperative morbidity.ResultsIn 174 patients (69% men; mean age 62.6 years) the mean operating time was 334.5 ± 92.1 min. Operative procedures included low anterior resection (n = 143) and intersphincteric resection (n = 31). For operating time, there were two or three (centre‐dependent) LC phases. After 12–21 cases (learning phase), there was a significant decrease in total operating time (all centres) and an increase in the number of harvested lymph nodes (two centres). For conversion rate, there were two or four LC phases. After 9–14 cases (learning phase), the conversion rate decreased significantly in two centres; in one centre, there was a nonsignificant decrease despite the treatment of significantly more obese patients and patients with previous abdominal surgery. There were no significant differences in interphase comparisons.ConclusionThe LC for RAS in rectal cancer was achieved after 12–21 cases for the operating time and 9–14 cases for the conversion rate. RAS for rectal cancer was safe during this time, with no interphase differences in postoperative complications and circumferential resection margin.
Assessment of pharmacokinetics, safety, and tolerability following twice‐daily administration of molnupiravir for 10 days in healthy participants
Authors: Iwamoto Marian , Duncan Kelly E. , Wickremasingha Prachi K. , Zhao Tian , Liberti Maria V. , Lemoine Lieselotte , Decaesteker Tatjana , Rottey Sylvie , Maas Brian M. , Gillespie Gillian , Stoch S. Aubrey 
Published: August 2023

AbstractMolnupiravir is an orally administered, small‐molecule ribonucleoside prodrug of β‐D‐N4‐hydroxycytidine (NHC) that has demonstrated potent, broad‐spectrum preclinical activity against RNA viruses and has a high barrier to the development of resistance. A double‐blind, placebo‐controlled, phase I trial was conducted to evaluate the pharmacokinetics (PKs), safety, and tolerability of 10.5‐day administration of multiple doses of molnupiravir and its metabolites in healthy, adult participants. Participants were randomly assigned (3:1) to receive molnupiravir (400 mg [n = 6], 600 mg [n = 6], and 800 mg [n = 12]) or matching placebo (n = 8) every 12 h (q12h) for 10.5 days. Blood was collected to evaluate the PKs of NHC in plasma and of its active metabolite, NHC‐triphosphate (NHC‐TP), in peripheral blood mononuclear cells (PBMCs). Molnupiravir was generally well‐tolerated. All adverse events were mild or moderate in severity and none led to treatment discontinuation. No clinically meaningful dose‐related safety findings were observed. Mean time to maximal concentration was ~1.50 to 1.98 h for plasma NHC and ~4.00 to 8.06 h for PBMC NHC‐TP. Accumulation was minimal (<1.2) for NHC and ~2‐ to 2.5‐fold for NHC‐TP. Plasma NHC PKs was generally dose proportional, and PBMC NHC‐TP PKs was less than dose proportional over the dose range studied. NHC and NHC‐TP PK support twice‐daily administration. Overall, molnupiravir administered at up to 800 mg q12h for 10.5 days was generally well‐tolerated in healthy participants with dose‐linear PKs, supporting the evaluation of longer molnupiravir dosing up to 10 days in future clinical trials.
Changes in employment status over time in multiple sclerosis following a first episode of central nervous system demyelination, a Markov multistate model study
Authors: Zarghami Amin , Fuh‐Ngwa Valery , Claflin Suzi B. , van der Mei Ingrid , Ponsonby Anne‐Louise , Broadley Simon , Simpson‐Yap Steve ,   Ausimmune/AusLong Investigator Group, Taylor Bruce V. 
Published: August 2023

AbstractBackground and purposeUnderstanding predictors of changes in employment status among people living with multiple sclerosis (MS) can assist health care providers to develop appropriate work retention/rehabilitation programs. We aimed to model longitudinal transitions of employment status in MS and estimate the probabilities of retaining employment status or losing or gaining employment over time in individuals with a first clinical diagnosis of central nervous system demyelination (FCD).MethodsThis prospective cohort study comprised adults (aged 18–59 years) diagnosed with FCD (n = 237) who were followed for more than 11 years. At each review, participants were assigned to one of three states: unemployed, part‐time, or full‐time employed. A Markov multistate model was used to examine the rate of state‐to‐state transitions.ResultsAt the time of FCD, participants with full‐time employment had an 89% chance of being in the same state over a 1‐year period, but this decreased to 42% over the 10‐year follow‐up period. For unemployed participants, there was a 92% likelihood of remaining unemployed after 1 year, but this probability decreased to 53% over 10 years. Females, those who progressed to clinically definite MS, those with a higher relapse count, and those with a greater level of disability were at increased risk of transitioning to a deteriorated employment state. In addition, those who experienced clinically significant fatigue over the follow‐up period were less likely to gain employment after being unemployed.ConclusionsIn our FCD cohort, we found a considerable rate of employment transition during the early years post‐diagnosis. Over more than a decade of follow‐up post‐FCD, we found that females and individuals with a greater disability and a higher relapse count are at higher risk of losing employment.
Arctic drones – A new security dilemma
Authors: Rogers James 
Published: August 2023

AbstractOver 100 countries now have a military drone programme comprised of either armed or unarmed systems. These drones are used to project power, fulfil national security objectives and signal political interest in disputed regions. As the climate crisis transforms parts of the Arctic, considerable investment is taking place in remote systems that can both monitor for ‘unwanted guests’ and engage in military activity. In this context, drones, specifically unarmed military drones, are becoming the favoured technology of Arctic states. Denmark, Iceland, Canada, Russia and the United States are all now using drones to protect national interests, symbolise sovereignty and enable a watchful eye to be cast on neighbours and newcomers, such as China. This article argues that while the introduction of military drones may be seen as stabilising in the first instance, in the longer term these systems are likely to escalate tensions, leading to a new drone‐based security dilemma. Of particular note is the ‘virtual’ net of detection being built by Russia. This net is reliant on drones, in partnership with additional military infrastructure and hardware, and has been developed by Moscow to establish a military capacity to detect and respond to external actors across and perhaps beyond the Russian Arctic.