bluuebunny/crossref_metadata_2025_split huggingface dataset:
Regioselective access to polycyclic N-heterocycles via homogeneous copper-catalyzed cascade cyclization of allenynes
Authors: Wei Kua-Fei , Liu Qing , Ma Guang , Jiang Xiao-Lei , Zhu Xiu-Hong , Ru Guang-Xin , Shen Wen-Bo 
Published: May 2023

AbstractPolycyclic N-heterocycles are important structural motifs commonly found in bioactive compounds, however, their selective construction via the cyclization of allenynes remains challenging yet highly desirable. Here we show a homogeneous copper-catalyzed hetero Diels−Alder (HDA) reaction of allenynes with cis-diazenes (PTAD, 4-phenyl-1,2,4-triazoline-3,5-dione), allowing the practical and efficient synthesis of a diverse array of valuable polycyclic N-heterocycles. A temperature-controlled and stereocontrolled chemoselectivity of the reaction was observed, leading to the chemodivergent synthesis of tetracyclic pyrrolidines, pentacyclic triazepanes and tricyclic pyrrolidines. Compared with related Au-catalyzed cyclization of allenynes, this copper catalysis achieves cyclization of allenynes terminating in C–N bond formation via the HDA reaction.
Bipotentiostatic tandem electrocatalysis of the CO2 reduction reaction yielding C2+ fuels
Authors: Kim Joo Yeon , Kim Yeonsu , Ryu C. Hyun , Ahn Hyun S. 
Published: May 2023

In the Cu–Ag bipotentiostatic CO2RR, C2+ selectivity was improved to 67.3%, including a 6.5% efficiency towards 1-propanol. The system-controlled CO delivery allowed the determination of the C–C coupling turnover frequency of 0.43 ± 0.06 s−1.
School-Based Speech-Language Pathologists' Engagement With Evidence-Based Practice: An Update With Implications for Implementation Research
Authors: Hall-Mills Shannon , Ireland Marie , Flynn Perry F. , Hoffman LaVae 
Published: May 2023

Purpose:We replicated a prior survey study (Hoffman et al., 2013) to document current evidence-based practice (EBP) patterns as reported by school-based speech-language pathologists (SLPs) during the 2021–2022 school year.Method:Via an online survey, SLPs reported their training experiences and needs, workplace resources, and frequency of engagement in EBP activities.Results:A total of 889 SLPs in 50 states participated in the survey. Results revealed that 19% of seasoned SLPs (with more than 10 years since last degree) had no formal training in EBP, 22% of SLPs worked in school districts with official EBP procedural guidelines, and 36% had scheduled time in their work week to support EBP activities. Early career (EC) professionals were more likely than seasoned career (SC) professionals to pose and research one or more EBP questions per year and to read journal articles about assessment and treatment. The gap in article use by experience groups was larger than a decade ago. Like prior survey results, the majority of SLPs read zero to four American Speech-Language-Hearing Association (ASHA) journal articles on assessment or intervention per year, with similar results for reading non-ASHA journal articles.Conclusions:Although the past decade has fostered some positive increases in the use of EBP resources and engagement in EBP activities, there continues to be a need for additional training and support for school-based SLPs to fully implement EBP. Training and implementation support should account for differences in training preferences and workplace resources and address differentiation of reported practices by EC versus SC professionals. Further implications for implementation science in schools are provided.Supplemental Material:https://doi.org/10.23641/asha.23152817
A review of blockchain cross‐chain technology
Authors: Li Li , Wu Jiahao , Cui Wei 
Published: May 2023

AbstractAlong with the continuous breakthroughs and innovations in blockchain technology, various blockchain application scenarios are emerging, such as healthcare, e‐voting, and Internet of Things. However, in general, these applications need to be supported by blockchain systems with different characteristics. Different blockchain systems have significant differences in architecture, security, efficiency, and so on, which makes the exchange of information between applications have certain barriers. Therefore, the research of blockchain cross‐chain technology brings hope for breaking the information barriers between blockchain systems. This paper describes the basic principles and latest research of three mainstream cross‐chain technologies; then analyzes three innovative cross‐chain solutions of cross‐chain routing, smart contracts, and multi‐chain consensus; furthermore, discusses the application and security risks of cross‐chain technologies, and finally summarizes and outlooks on cross‐chain technologies.
A reconfigurable dual‐band low noise amplifier for 5G in 65‐nm CMOS
Authors: Wen Jincai , Yu Meng 
Published: May 2023

AbstractIn this paper, a reconfigurable low noise amplifier (LNA) is proposed for 5G dual‐bands in a 65‐nm CMOS process. The reconfigurable function of LNA is realized by designing reconfigurable matching networks composed of transformers and MOS transistor switches. The pole characteristics of the resonant network composed of the reconfigurable network and the equivalent circuit of the amplifying device are deduced and analyzed in detail. By establishing the relationship between two reconfigurable frequencies and the ratio of transformer coil inductance under two switching states, the position of the switch and the specific parameters of the reconfigurable matching network are determined. Measurement results show small‐signal gain of 25.5 to 33.9 dB and noise figure of 3.3 to 4.3 dB at 24 to 29.5 GHz bands, and small‐signal gain of 23.5 to 27.8 dB and noise figure of 4.3 to 4.5 dB at 37 to 40 GHz bands, respectively. The chip area occupied 0.34 mm2 including pads.
SIW‐backed multiplexing slot antenna for multiple wireless system integration
Authors: Chaturvedi Divya , Kumar Arvind , Althuwayb Ayman A. , Ahmadfard Farnaz 
Published: May 2023

AbstractIn this letter, a planar cavity‐backed multiplexing antenna (SMA) is proposed and validated experimentally. A planar cavity is realized by using a novel transmission line known as substrate‐integrated waveguide (SIW) technology. The design comprises five SIW cavities and each one consisting of a slot for launching the energy in free space. Three different types of slots are employed for lower mutual coupling and compact circuit integration. The individual feeds are created in such a way, that antenna produces five distinct resonant frequencies in the dominant mode while maintaining sufficient mutual port isolation. Finally, the proposed concept is validated with experiments and results show acceptable agreement with the simulated counterparts. The design shows five operating frequency channels with center frequencies of 5.2, 5.5, 5.75, 6.2, and 6.8 GHz. The mutual isolation between any two radiating elements retains below −21 dB and the average gain of the antenna is better than 3.5 dBi at each resonant frequency. The proposed SMA element can be used to cover a wide range of wireless access points and seems suitable for multiple wireless system integration.
Encoding and decoding‐based normalizing flows for image anomaly localization
Authors: Lee Kibae , Ko Guhn Hyeok , Lee Chong Hyun 
Published: May 2023

AbstractThe authors propose encoding and decoding network‐based normalizing flows (EaD‐Flow) for the detection and localization of anomalies in an image. Multiple networks of the EaD‐Flow estimate probability densities of tenor image. The anomaly localization model based on multiple networks shows superior anomaly detection and localization performance.
A rail‐to‐rail regenerative comparator with inverse inverter pre‐amplifier for low supply voltage applications
Authors: Pahlavanzadeh Hadi , Iesakhani Saba , Karami Mohammad Azim 
Published: May 2023

AbstractIn this letter, a new rail‐to‐rail two‐stage regenerative comparator for low supply voltage applications is presented. A rail‐to‐rail operation is achieved by utilizing an inverse inverter pre‐amplifier. The proposed comparator is post‐layout simulated within a standard 180‐nm CMOS technology. In the worst‐case scenario, the energy efficiency and the delay of the comparator are improved by more than 80% compared to the conventional single‐stage comparator.
Magnetic circuit decomposition model and novel inner‐turn fault protection scheme for shunt reactor with auxiliary windings
Authors: Zheng Tao , Tian Haoyu , Meng Lingkun 
Published: May 2023

AbstractShunt reactor with auxiliary windings (SRAW) can compensate inductive reactive power for long‐distance transmission lines and supply steady power for low‐voltage devices on offshore platforms. The operation characteristics of SRAW can be commonly described by the air‐core transformer equivalent model. However, this model can only make an approximate simulation of the external characteristics of SRAW, and cannot reflect the actual electrical features inside the SRAW. To solve this problem, the authors propose a three‐segment magnetic circuit equivalent model (TMCEM) of SRAW based on the magnetic circuit decomposition method. This model can accurately describe the coupling relationship inside SRAW and can be used for the analysis of internal fault characteristics. Furthermore, through the fault analysis utilizing TMCEM, a novel protection scheme of SRAW based on virtual magnetizing differential current is proposed for the detection of the inner‐turn fault in SRAW. This protection scheme has high sensitivity and can effectively identify the inner‐turn faults without measuring voltages. By testing the physical model of SRAW, the effectiveness of the TMCEM and the proposed protection scheme against inner‐turn fault has been confirmed.
Direct current (DC) microgrid control in the presence of electrical vehicle/photovoltaic (EV/PV) systems and hybrid energy storage systems: A Case study of grounding and protection issue
Authors: Taheri Behrooz , Shahhoseini Ali 
Published: May 2023

AbstractIn recent years, the interest in using DC microgrids has greatly increased due to their higher efficiency, less complexity, and greater transmission power compared to AC microgrids. To address challenges in DC microgrids in the presence of electrical vehicles (EVs) and the uncertainty of charging EVs, researchers have used PV/EV combination systems with energy storage systems (ESS). Controlling DC microgrids, including PV/EV/ESS, is crucial to cope with the existing challenges. On the other hand, the research on DC microgrids' protection systems is in the early stages, and there are still many challenges in this field. In addition, differences in control systems can pose different challenges for the protection system. The simulation results in this paper demonstrate that considering the best case (use of unipolar resistance grounding system) the DC bus voltage is improved by 22.3% (based on MAPE% data comparison). In the protection part, the empirical‐mode decomposition (EMD) method and selecting a suitable intrinsic mode functions (IMF) have been used to protect the DC microgrid. The proposed protection method has been tested under pole‐to‐pole and pole‐to‐ground fault conditions. The results show that the proposed method is capable of detecting various fault types in the studied microgrid.
An improved auxiliary circuit for IPT systems to achieve inherent CC‐to‐CV transition and load fault‐tolerant operation
Authors: Ren Sheng , Yang Ping , Wang Xiaoqiang , Xu Jianping 
Published: May 2023

AbstractThree‐coil inductive power transfer (IPT) charging system can not only achieve inherent constant current (CC) to constant voltage (CV) transition but also tolerate load open‐circuit. However, due to the cross‐coupling between the auxiliary coil and the receiver coil, the output voltage in CV mode may deviate from the CV voltage significantly, which makes the design freedom of the three‐coil coupler low. By replacing the auxiliary coil with a transformer, an improved auxiliary circuit is proposed in this paper to address the cross‐coupling issue and to increase the design freedom of the loosely coupled transformer (LCT). The improved auxiliary circuit can achieve load short‐circuit and open‐circuit protection. Besides, the optimization design of LCT is easy to achieve by load impedance matching. The operating principle and parameters design of the improved auxiliary circuit are discussed. A 1 kW experimental prototype is built to verify the feasibility of the proposed method.
KMT-2021-BLG-1150Lb: Microlensing planet detected through a densely covered planetary-caustic signal
Authors: Han Cheongho , Jung Youn Kil , Bond Ian A. , Gould Andrew , Chung Sun-Ju , Albrow Michael D. , Hwang Kyu-Ha , Ryu Yoon-Hyun , Shin In-Gu , Shvartzvald Yossi , Yang Hongjing , Yee Jennifer C. , Zang Weicheng , Cha Sang-Mok , Kim Doeon , Kim Dong-Jin , Kim Seung-Lee , Lee Chung-Uk , Lee Dong-Joo , Lee Yongseok , Park Byeong-Gon , Pogge Richard W. , Abe Fumio , Barry Richard , Bennett David P. , Bhattacharya Aparna , Fujii Hirosame , Fukui Akihiko , Hamada Ryusei , Hirao Yuki , Ishitani Silva Stela , Itow Yoshitaka , Kirikawa Rintaro , Kondo Iona , Koshimoto Naoki , Matsubara Yutaka , Matsumoto Sho , Miyazaki Shota , Muraki Yasushi , Okamura Arisa , Olmschenk Greg , Ranc Clément , Rattenbury Nicholas J. , Satoh Yuki , Sumi Takahiro , Suzuki Daisuke , Toda Taiga , Tomoyoshi Mio , Tristram Paul J. , Vandorou Aikaterini , Yama Hibiki , Yamashita Kansuke 
Published: May 2023

Aims. Recently, there have been reports of various types of degeneracies in the interpretation of planetary signals induced by planetary caustics. In this work we check whether such degeneracies persist in the case of well-covered signals by analyzing the lensing event KMT-2021-BLG-1150, the light curve of which exhibits a densely and continuously covered short-term anomaly.
Methods. In order to identify degenerate solutions, we thoroughly investigated the parameter space by conducting dense grid searches for the lensing parameters. We then checked the severity of the degeneracy among the identified solutions.
Results. We identify a pair of planetary solutions resulting from the well-known inner-outer degeneracy, and find that interpreting the anomaly is not subject to any degeneracy other than the inner-outer degeneracy. The measured parameters of the planet separation (normalized to the Einstein radius) and mass ratio between the lens components are (s, q)in ~ (1.297, 1.10 × 10−3) for the inner solution and (s, q)out ~ (1.242, 1.15 × 10−3) for the outer solution. According to a Bayesian estimation, the lens is a planetary system consisting of a planet with a mass Mp = 0.88−0.36+0.38 Mj and its host with a mass Mh = 0.73−0.30+0.32 M⊙ lying toward the Galactic center at a distance DL = 3.8−1.2+1.3 kpc. By conducting analyses using mock data sets prepared to mimic those obtained with data gaps and under various observational cadences, we find that gaps in data can result in various degenerate solutions, while the observational cadence does not pose a serious degeneracy problem as long as the anomaly feature can be delineated.
Incendies Dispositifs, objectivations et figures du surmoi de notre modernité
Authors: Lévy Alexandre 
Published: May 2023

Notre travail aborde certaines conséquences psychopathologiques des dispositifs modernes, notamment ceux liés à la gestion des ressources humaines et au management. L’hypothèse de travail ici développée est que le renouvellement formel des symptômes est à la mesure des formes modernes d’aliénations sociales ainsi que des divers modes de jouissances mis à disposition, tout en soulignant plus fondamentalement le pouvoir du signifiant sur l’orientation de la jouissance du parlant. Notre démarche procède d’une réflexion menée à partir de la clinique de l’épuisement professionnel aussi bien que celle de l’addiction dans ses diverses formes, nous invitant à dégager l’implication de l’objet petitaainsi que des formes actualisées et renouvelées du surmoi freudien, différentes des formes issues du « Malaise dans la civilisation », initialement paru en 1929.
Telemedizin in der Kardiologie – was ist neu?
Authors: Schneider David , Köhler Kerstin , Köhler Friedrich 
Published: May 2023

Was ist neu?
Aktuelle Leitlinien zum Telemonitoring bei chronischer Herzinsuffizienz Die telemedizinische Mitbetreuung führt bei Risikopatienten zur Reduktion von Herzinsuffizienz-Hospitalisierungen und zu einer Lebensverlängerung. Deshalb hat der Gemeinsame Bundesausschuss (G-BA) das Telemonitoring bei Patienten mit einer Herzinsuffizienz als eigenständige Methode anerkannt und zur Abrechnung als Regelleistung der gesetzlichen Krankenkassen zugelassen. Damit haben seit 2022 in Deutschland ca. 200000 Patient*innen einen Anspruch auf eine telemedizinische Mitbetreuung. Die Implementierung in den kardiologischen Praxisbetrieb ist komplex, weil sie neben der Einführung der telemedizinischen Technik die Strukturierung zahlreicher Prozesse wie Patientenschulungen, die Erarbeitung von „Standard operation procedures” (SOPs) beim Vitaldatenmonitoring sowie Qualitätssicherungsmaßnahmen umfasst.
Aktuelle Studienlage In den letzten 3 Jahren wurden mehrere randomisierte klinische Studien, überwiegend mit dem Ziel der Indikationserweiterung, durchgeführt. Dazu wurden mit der bereits in vorangegangenen Studien positiv geprüften Telemedizintechnologie neue Patientengruppen untersucht. Die größte Studie bildete dabei die GUIDE-HF-Studie mit 1022 Patienten im funktionellen Stadium NYHA II–IV, in der ein hämodynamisch basiertes Telemonitoring getestet wurde. Bereits im Jahr 2011 war mit der gleichen Technologie in der CHAMPION-Trial-Studie eine signifikante Senkung von Herzinsuffizienz-Hospitalisierungen nachgewiesen worden. Die GUIDE-HF-Studie zeigte ein neutrales primäres Studienergebnis. Als ursächlich gilt der Einfluss der COVID-Pandemie auf den Studienverlauf.
Innovative telemedizinische Sensortechnologien Entwicklungsschwerpunkt in der Telemedizintechnik bilden aktuell neue Sensoren für eine bessere klinische Charakterisierung des pulmonalen Flüssigkeitsstatus. Neben dem bisher alleinigen System zur drahtlosen Messung des Pulmonalisdrucks mit dem System CARDIOMEMS gibt es jetzt ein weiteres System (Cordella). Außerdem ist nun ein System zur drahtlosen Messung des linksatrialen Drucks (V-LAP) verfügbar. Ein weiterer Forschungsansatz ist die Stimmanalyse von Patienten über ein Smart Device, in der eine Bewertung des pulmonalen Flüssigkeitsstatus möglich sein könnte. Dabei kommen Verfahren der Künstlichen Intelligenz zur Anwendung.
Clostridioides difficile – Neue Erkenntnisse und Therapieempfehlungen
Authors: Schönherr Sebastian , Jung Laura , Lübbert Christoph 
Published: May 2023

Was ist neu?
Epidemiologie In einer aktuellen epidemiologischen Arbeit zeigt sich ein seit 2013 rückläufiger Trend von Clostridioides-difficile-Infektionen (CDI) in Deutschland, zusammen mit einer Abnahme des Anteils hypervirulenter Ribotypen (vor allem RT 027 und RT 078). Dennoch bleibt die Krankheitslast hoch und insbesondere ältere und vorerkrankte Patientinnen und Patienten sind häufig betroffen. Aktuelle US-amerikanische Daten zeigen, dass bei älteren Patientinnen und Patienten insbesondere CDI-Rezidive, assoziierte psychiatrische Diagnosen wie Depressionen sowie Folgeerkrankungen wie Sepsis eine hohe Krankheitslast für Betroffene darstellen.
Mikrobiologie Neue Studien liefern Erkenntnisse zum Zusammenspiel von C. difficile mit anderen Darmpathogenen; so scheinen Koinfektionen mit Enterokokken zu einer erhöhten Virulenz von C. difficile beizutragen.
Neue europäische Therapieleitlinie Nach der 2021 aktualisierten ESCMID-Leitlinie ist Fidaxomicin aufgrund des geringeren Rezidivrisikos Mittel der ersten Wahl für erstmalig auftretende und rezidivierende CDI. Metronidazol dagegen sollte nur dann zum Einsatz kommen, wenn weder Fidaxomicin noch Vancomycin zur Verfügung stehen. Die fäkale Mikrobiota-Transplantation (FMT) hat sich im Rahmen eines individuellen Heilversuchs zur Behandlung mehrfach rezidivierender CDI etabliert; allerdings wurden die regulatorischen Auflagen dafür im Zuge der Corona-Pandemie weiter verschärft. Auch bei refraktär verlaufender fulminanter CDI kann die FMT als Alternative zur chirurgischen Intervention erwogen werden.
Weitere Behandlungsmöglichkeiten Mit dem Small-Molecule-Antibiotikum Ridinilazol könnte in Zukunft neben Fidaxomicin ein weiteres CDI-Antibiotikum mit schmalem Wirkspektrum und kaum enteraler Resorption zur Verfügung stehen. Die orale Mikrobiota-Therapie mittels aufgereinigter Firmicutes-Sporen (SER-109) zeigte in einer aktuellen Phase-III-Studie vielversprechende Ergebnisse und könnte in Zukunft durch die Anwendung in oralen Kapseln eine unkomplizierte Alternative zur FMT darstellen.
Toxoid-Impfstoff Die Hoffnungen auf einen gut wirksamen Toxoid-Impfstoff zur Primär- und Sekundärprävention von CDI haben sich in der CLOVER-Studie leider nicht erfüllt.
Evolving the Cybersecurity of Clinical Photography in Plastic Surgery
Authors: Spoer Daisy L. , Junn Alexandra , Bovill John D. , Haffner Zoë K. , Abadeer Andrew I. , Baker Stephen B. 
Published: May 2023

AbstractPoint-of-care photography and photo sharing optimize patient outcomes and facilitate remote consultation imperative for resident surgeons. This literature review and external pilot survey study highlight the risks associated with current practices concerning patient privacy and biometric security. In a survey of 30 plastic surgeon residents and attendings, we found that the majority took photos of patients with their iPhones and shared them with colleagues via Apple iMessage. These findings corroborate previous reports and highlight a lack of physician user acceptance of secure photo-sharing platforms. Finally, we frame a successful example from the literature in the context of a postulated framework for institutional change. Prioritizing the privacy and safety of patients requires a strategic approach that preserves the ease and frequency of use of current practices.
Anesthetic Fade in Intraoperative Transcranial Motor Evoked Potential Monitoring Is Mainly due to Decreased Synaptic Transmission at the Neuromuscular Junction by Propofol Accumulation
Authors: Tanaka Satoshi , Yamamoto Kenta , Yoshida Shinsuke , Tomio Ryosuke , Fujimoto Takeshi , Osaka Misuzu , Ishikawa Toshio , Shimizu Tsunemasa , Akao Norio , Nishimatsu Terutaka 
Published: May 2023

Abstract
Background We previously reported that normalization of motor evoked potential (MEP) monitoring amplitude by compound muscle action potential (CMAP) after peripheral nerve stimulation prevented the expression of anesthetic fade (AF), suggesting that AF might be due to reduced synaptic transfer in the neuromuscular junction.
Methods We calculated the time at which AF began for each of craniotomy and spinal cord surgery, and examined whether AF was avoided by CMAP after peripheral nerve stimulation normalization in each. Similar studies were also made with respect to the upper and lower limb muscles.
Results AF was observed in surgery lasting 160 minutes for craniotomy and 260 minutes or more for spinal surgery, and 195 minutes in the upper limb muscles and 135 minutes in the lower limb muscles. In all the series, AF could be avoided by CMAP after peripheral nerve stimulation normalization.
Conclusion AF of MEP occurred in both craniotomy and spinal cord surgery, and it was also corrected by CMAP after peripheral nerve stimulation. AF is considered to be mainly due to a decrease in synaptic transfer of the neuromuscular junction due to the accumulation of propofol because of the avoidance by CMAP normalization. However, it may be partially due to a decrease in the excitability of pyramidal tracts and α-motor neurons, because AF occurred earlier in the lower limb muscles than in the upper limb muscles.