bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prognostic value of iron metabolism-related genes in bladder urothelial carcinoma
Authors: Lu Hezhen , Yue Siqi , Yang Zhaowei , He Chengyan , Pan Junqi 
Published: May 2023

Abstract

Objectives
Iron metabolism-related genes (IMRGs) play important roles in the prognostic assessment of many tumours. However, IMRGs have not been reported as prognostic biomarkers in bladder urothelial carcinoma (BLCA).

Methods
Gene expression profiles and clinical data from BLCA patients were obtained from The Cancer Genome Atlas (TCGA) database. We used the DESeq2 package to screen for differentially expressed genes (DEGs). The predictive values of the differentially expressed IMRGs in BLCA patients were further evaluated using univariate Cox regression analysis. The risk-scoring model was constructed using the least absolute shrinkage and selection operator (LASSO) algorithm. The performance of this model for predicting the prognosis of BLCA patients in TCGA-BLCA cohort was assessed using Kaplan–Meier (K–M) and receiver operating characteristic (ROC) curves. This risk-scoring model was combined with the clinicopathological characteristics of BLCA patients in a multiple regression analysis, and a nomogram was constructed using the independent predictors identified. ROC analysis and calibration curves were adapted to test the predictive ability of the nomogram. Gene set enrichment analysis (GSEA) was used to identify potential molecular pathways and processes enriched by differential expression genes between risk groups. Finally, we explored the ability of the risk-scoring model to assess immune cell infiltration levels through a correlation analysis.

Results
Fourteen identified IMRGs with prognostic value were incorporated into the risk-scoring model. The ROC and K–M survival curves indicated that the model could effectively predict the overall survival (OS) outcomes of BLCA patients. The multiple regression analysis revealed that the risk-scoring model could be used as an independent prognostic factor for BLCA patients, and the associated nomogram could effectively predict the OS outcomes of BLCA patients. GSEA revealed that the DEGs between the risk groups were mainly involved in biological processes such as developmental process, cell cycle, mitosis, RHO GTPase reaction, DNA repair, and extracellular matrix regulation. The immune infiltration analysis showed that the infiltration levels of immune cells such as natural killer cells, memory T cells, effector T cells, Th2 cells, and macrophages differed significantly between the risk groups.

Conclusions
IMRGs screening revealed prognosis-associated genes. The prognostic model constructed could effectively predict the prognosis of BLCA patients, and the identified genes represent potential targets for BLCA treatment.
Managing the Vague: John Dewey’s Aesthetics and the Relation of Fine Art and Mathematics
Authors: Ruoppa Raine 
Published: May 2023

Abstract
In philosophical discourse, vagueness is commonly regarded as an undesirable and problematic aspect of human experience. Such standpoints are not unfounded. However, in this article, I argue that vagueness may in certain instances also possess an instrumental role that supports specific modes of human aspiration, including the artistic and the mathematical. In particular, I investigate the ways in which vagueness not only hinders but also fosters the emergence of an aesthetic quality of experience during the imaginative endeavours of fine art and mathematics. The manner in which the benefit from felt vagueness ties into the formation of artistic and mathematical scenarios helps to illuminate deep and often unnoticed relations between these two domains of human ingenuity. In this article, the overall concept of experience and the particular features of human experience, such as the aesthetic and the vague, are examined in the context of John Dewey’s philosophical pragmatism. In Dewey’s philosophical framework, the human mind and culture are understood as natural phenomena. As such, the Deweyan approach fits the paradigm of a twenty-first century scientific understanding of the inherent ontological unity of all modes of human existence and activity.
Aprendizes de passarinho: uma experiência de arte no/do/com o campo
Authors: Damé Paulo Renato Viegas , Marques Angélica de Sousa , Pinto Fábio Machado , Damé Gabriela de Moraes 
Published: May 2023

Esse texto é resultado de uma construção coletiva e tem como objetivo refletir sobre a educação e as relações possíveis nas condições vividas em tempo de pandemia - de confinamento, como forma de resistir, no entorno do dispositivo artístico Casa Redonda. Problematizamos a relação com o meio, a Casa na fase do habitar, dos trabalhos e estudos de maneira remota, a educação das crianças e as relações sociais e sociológicas, ressignificando a função da arte ao enfrentamento da crise.Palavras-chave: Arte. Educação. Sustentabilidade. Infância. Pandemia. A little bird’s Apprentices: An art experience with/of/in the fieldAbstract: This paper is a result of collective collaboration and has, as its objective, critical reflection about education and the living conditions experienced during the pandemic and its ensuing confinement, seen as a form of resistance, as we consider the artistic dispositif Casa Redonda [Round House]. Issues are raised about relationships with/to the environment, such as the House in a situation of dwelling, as a work place for remote access studies, educating children at home and social and sociological relationships, which re-signify the function of art in the face of crisis.Keywords: Art. Education. Sustainability. Childhood. Pandemic
Uma Aula
Authors: Campello Ronaldo Luis , Guapacha Marisela 
Published: May 2023

Uma aula é um texto escrito por dois docentes, uma colombiana e um brasileiro que dizem de si, de seus estudantes e de suas experiências de realização de um projeto de escrita de cartas ocorrido no ano de 2019. Uma aula é um texto que busca na filosofia da diferença suporte teórico para pensar sua escrita e dar aporte a conceitos que ajudam a pensar as práticas, experiências e encontros aqui experienciados.Palavras-chave: Cartas epistolares. Cartografia. Ler/Escrever. Aferente/eferente. Una Clase Resumen: Una clase es un texto escrito por dos docentes, una colombiana y otro brasileño que dicen de sí, de sus estudiantes y de la experiencia de la realización de un proyecto de escritura de cartas ocurrido en el año 2019. Una clase es un texto que busca en la filosofía de la diferencia soporte teórico para pensar su escritura y dar un aporte a conceptos que ayudan a pensar las prácticas, experiencias y encuentros aquí experienciados.Palabras clave: Cartas epistolares. Cartografía. Leer/Escribir. Aferente/eferente.
Aproximações entre bioma pampa e ecofeminismo desde a educação ambiental crítica
Authors: Behling Greici Maia 
Published: May 2023

A Educação Ambiental Crítica tende a perceber que os problemas ambientais contemporâneos não encontram respostas em soluções disciplinares e reducionistas. Desta forma, compreende que os processos de exploração do bioma Pampa estão assentados em questões construídas socialmente, a partir de um sistema de dominação e opressão da natureza. Nesse sentido, compreende-se que a dominação da natureza está inter-relacionada com o patriarcado e a dominação do feminino. Assim, este artigo objetivou tecer pontos de convergência entre o bioma Pampa e o ecofeminismo, diante do olhar da educação ambiental crítica.Palavras-chave: Educação ambiental crítica. Ecofeminismo. Bioma Pampa.Approximations between the Pampa biome and Ecofeminism from Critical Environmental EducationAbstract:Critical Environmental Education tends to acknowledge that contemporary environmental problems do not respond well to disciplinary and reductionist solutions. We find that the processes of exploration of the Pampa biome are based on socially constructed issues which arise from a system that dominates and oppresses nature. Therefore, we comprehend that the domination of nature is interrelated with patriarchy and the domination of the feminine. Thus, this article seeks to reveal points of convergence between the pampa biome and ecofeminism from the perspective of critical environmental education.Keywords: Critical environmental education. Ecofeminism. Pampa biome
Ensaio para o Amanhã: Olhares distintos acerca de uma cidade singular
Authors: Higa Daniel , Cunha Gabriela , Nascimento Karina , Senna Nádia da Cruz 
Published: May 2023

Resumo: [RESENHA DE EXPOSIÇÃO] Mostra Virtual Internacional Ensaio parao Amanhã: Olhares distintos acerca de uma cidade singular foi uma exposiçãocoletiva que integrou às ações desenvolvidas junto ao Seminário InternacionalEnsino da Arte - IV SIEA: arte e meio ambiente, realizado de 05 a 19 de outubro de2020, na Universidade Federal de Pelotas, Pelotas, RS, Brasil, (com link disponívelem: https://www.instagram.com/iimostravirtual/).Palavras-chave: Mostra virtual. Arte. Meio ambiente.Essay for the future: Different perspectives from a unique cityAbstract: [EXHIBITION REVIEW] \The International Virtual Exhibition Essay for thefuture: Different perspectives from a unique city was a group show which played anintegral role in the events presented during the International Seminar of Art Education- IV SIEA: art and the environment, which took play between the 5th and the19th of October, 2020, at the Centro de Artes, Federal University of Pelotas/UFPel,Pelotas, RS, Brazil, (link in: https://www.instagram.com/iimostravirtual/).Keywords: Virtual show. Art. Environment.
Espacios, Lugares y Paisajes en el Cine: El caso de la ciudad de Peñíscola.
Authors: Pérez García Jesús 
Published: May 2023

El espacio es algo inherente al cine, arte del movimiento. La ciudad de Peñíscola, en España, ha venido siendo desde los inicios del cine un lugar apropiado para la producción cinematográfica, tanto por sus construcciones históricas como por sus posibilidades geográficas. Desde el primer rodaje, en 1913, se han filmado veintidós películas, usando el espacio de la ciudad de diferentes formas que en este artículo se categorizan en tres: como paisaje, como escenario y como espacio vivido.Palabras clave: Espacio; Lugar; Paisaje; Cine, Peñíscola. Espaços, Lugares e Paisagens no Cinema: O caso da cidade de Peñíscola.Resumo: O espaço é algo inerente ao cinema, a arte do movimento. A cidade de Peñíscola, na Espanha, tem sido desde os primórdios do cinema um lugar propício para a produção cinematográfica, tanto por suas construções históricas quanto por suas possibilidades geográficas. Desde a primeira filmagem, em 1913, já foram rodados vinte e dois filmes, utilizando o espaço da cidade de diferentes formas que neste artigo se categorizam em três: como paisagem, como cenário e como espaço vivido.Palavras-chave: Espaço, lugar, paisagem, cinema, Peñíscola.
Eixo do Mundo, de Marta Martins Costa
Authors: Motta Gabriela 
Published: May 2023

[RESENHA DE EXPOSIÇÃO] Esta resenha é sobre a exposição Eixo doMundo, realizada na Sala de Múltiplos Usos II, do Centro Histórico-Cultural (CHC)da Santa Casa de Porto Alegre (de novembro de 2021 a janeiro de 2022), da artista Marta Martins Costa, a partir da relação da obra da artista com a natureza.Palavras-chave: Eixo do Mundo.World Axis, by Marta Martins CostaAbstract: [EXHIBITION REVIEW] This review is about the exhibition Eixo do Mundo (World Axis), which took place at the Multiple Use Room of the Historical Cultural Center (CHC) of Santa Casa (hospital) in Porto Alegre, RS, Brazil (from november of 2021 to January of 2022), focusing on the artist Marta Martins Costa, and her work relating art and nature. Keywords: World Axis.
Pendugaan Musim Penangkapan Ikan Cakalang (Katsuwonus pelamis) dengan Alat Tangkap Pancing Ulur yang Didaratkan di Pangkalan Pendaratan Ikan (PPI) Oeba Kupang
Authors: Herawaty Susy , Arifin Hadjrah , Usman Luthfiah 
Published: May 2023

Provinsi Nusa Tenggara Timur memiliki potensi sumberdaya ikan yang sangat beragam jenisnya. Ikan cakalang (Katsuwonus pelamis) tergolong sumberdaya perikanan pelagis penting dan merupakan salah satu komoditi ekspor yang di daratkan di Pangkalan Pendaratan Ikan Oeba Kupang. Sumberdaya perikanan ini sudah dieksploitasi dan dimanfaatkan terus menerus hingga sekarang. Penelitian ini bertujuan untuk mengkaji musim penangkapan ikan cakalang di PPI Oeba Kupang, berdasarkan alat tangkap pancing ulur. Metode yang digunakan untuk pendugaan musim penangkapan ikan cakalang yaitu survey dengan pendekatan deskriptif. Data yang dikumpulkan adalah data produksi, data jumlah kapal perikanan, data jumlah alat tangkap/trip penangkapan pancing ulur dari tahun 2013-2017. Data dianalisis menggunakan Metode Persentase Rata-rata (The Average Percentage Methods) yang didasarkan pada Analisis Runtun Waktu (Times Series Analysis). Dari hasil analisis di dapat Indeks musim cakalang terjadi pada bulan Juni 116,42%, Agustus 109,61%, September 103,98% dan November 133,20%. Puncak indeks musim penangkapan cakalang terjadi pada bulan Oktober 297,60%.
Teknik Insersi Nucleus dan Penanganan Pasca Operasi Tiram Mutiara (Pinctada maximma)
Authors: Budiyati Budiyati , Yunarty Yunarty , Renitasari Diana Putri , Anton Anton , Supryady Supryady , Kurniaji Ardana , Saridu Siti Aisyah , Ihwan Ihwan , Indrifah Rani 
Published: May 2023

Kerang Mutiara adalah salah satu peluang usaha yang mempunyai prospek yang perlu dikembangakan karena harga jualnya yang tinggi. Tujuan studi ini adalah observasi pemasangan inti dan penanganan pasca opersi tiram Mutiara yang tepat. Metode yang digunakan adalah surve, dengan jenis data primer dan sekunder. Penelitian ini terdiri dari penanganan sebelum operasi, pemasangan inti Mutiara bulat, penanganan pasca operasi dan hasil Mutiara.Teknik insersi dibagi menjadi dua yakni ato dan saki okuri. Studi ini menggunakan ato okuri. Pemilihan bibit berdasarkan ukuran gonad dan umur. Teknik insersi dilakukan dengan memasukan ini kedalam gonad dan satu lembar saibo untuk melekatkan inti di bagian ectoderm. Hal yang perlu diperhatikan peralatan operasi harus sSteril, pembuatan sayatan, penempatan inti yang tepat dan cepat. Paca operasi tiran dimasukan ke dalam air secara hati-hati dan cepat. Kualitas Mutiara yang dihasilkan studi ini terdiri dari shine, surface, shade, shape dan size yang bagus. Rekomendasi untuk penelitian selanjutnya adalah hasil kualitas mutiara dari pemasangan inti bulat, setengah bulat atau berbentuk oval. Selain itu juga melihat bagimana tingkat kelangsungan hidup dan pertumbuhan kerang mutriara dengan pemasangan inti yang berbeda.
Pemetaan Zonasi Kawasan Konservasi Perairan Daerah Tana Lili Kabupaten Luwu Utara dengan Menggunakan Sofware Marxan
Authors: Rombe Katarina Hesty , Surachmat Agus , Surachmat Agus , Rusdi Yusriadi , Rusdi Yusriadi 
Published: May 2023

Salah satu kawasan konservasi perairan yang telah dicadangkan oleh pemerintah dalam hal ini Dinas Kelautan Provinsi Sulawesi Selatan yang telah dimuat dalam Dokumen Rencana Zonasi Wilayah Pesisir dan Pulau-Pulau Kecil (RZWP-3-K) tahun 2019 adalah KKPD TanaLili dengan luas 1.512,34 Ha. Setelah dicadangkan sejak tahun 2019 hingga sekarang belum memiliki rencana pengelolaan dan zonasi. Penelitian ini dilakukan dengan tujuan: (1) Memetakan sebaran ekosistem wilayar pesisir kawasan konservasi perairan Tana Lili, (2)Memetakan zonasi kawasan konservasi perairan daerah Tana Lili. Penelitian ini dilaksanakan pada Maret-Juni 2021.Pembuatan peta zonasi menggunakan software Marxan. Data citra satelit yang sudah diunduh kemudian dilakukan diproses melalui beberapa tahap, yaitu koreksi radiometerik, koreksi geometric, masking & cropping, komposit dan penajaman citra dan ground truth. Hasil penelitianmenunjukkan bahwa sebaran ekosistem mangrove seluas 34,21 Ha, ekosistem padang lamun seluas 35,95 Ha dan ekosistem terumbu karang seluas 140,39 Ha. Peta zonasi menunjukan Zona Inti seluas 71,34 Ha, Zona Pemanfaatan Terbatas yang terdiri atas subzona Perikanan Tangkap dengan luas sekitar 979,83 Ha, Subzona Pariwisata Budidaya dengan luas 316,43 Ha, Subzona Wisata Bahari dengan luas sekitar 11,04 Ha
THE USE OF ULTRASOUND TOMOGRAPHY TO IMPROVE ULTRASOUND CONTROL EFFICIENCY
Authors: Azylgareeva A. A. , Valiakhmetov R. I. 
Published: May 2023

To ensure safe and reliable operation of pipeline systems, it is necessary to regularly carry out work on technical diagnostics. Ultrasonic inspection is one of the most common methods for pipeline technical condition determining. It has many advantages over other control methods among which there can be distinguished accessibility, the absence of additional requirements for equipping the object under examination, the absence of an impact on the object of control itself, and safety. But ultrasonic inspection also has disadvantages some of which can be eliminated by using an individual piezo elements of multi-element transducer instead of simple single-element transducers.
The method of pipeline wall thickness determining using piezo elements of a multi-element transducer, as well as searching for and identifying the type and size of the defect, is known as ultrasonic tomography.
This paper presents the main features of the transducers used in ultrasonic tomography, possibilities of ultrasonic tomography when it is used in field pipeline diagnostics. The advantages of using the method of ultrasonic tomography in comparison with conventional ultrasonic control are considered.
Distribución, estado de conservación y amenazas de Lobelia villaregalis (Campanulaceae) en el Bosque La Primavera, Jalisco
Authors: Hernández-López Leticia , Munguía-Lino Guadalupe 
Published: May 2023

Antecedentes: Lobelia villaregalis fue descrita en 1987 a partir de una sola localidad en el Bosque La Primavera, Zapopan, Jalisco. En el año 2008 se registró otra localidad, lo que sugiere que el conocimiento sobre la distribución de la especie es incompleto.
Preguntas: ¿Cuál es la distribución conocida y potencial de L. villaregalis en el Bosque La Primavera? ¿Cuál es su estado de conservación y cuáles las principales amenazas?
Especies de estudio: Lobelia villaregalis T.J. Ayers.
Sitio de estudio y fechas: Zapopan, Jalisco, 2018-2020.
Métodos: Se realizaron exploraciones en el área natural protegida Bosque La Primavera para localizar poblaciones nuevas de la especie. Para caracterizar el hábitat y las amenazas que enfrenta la especie se registraron datos en campo y se complementaron utilizando sistemas de información geográfica. También se determinó su estado de conservación. La distribución potencial se obtuvo con Maxent.
Resultados: Se registran en total seis sitios con presencia de L. villaregalis, los cuales se ubican en las zonas de manejo de mayor protección; Uso restringido y Recuperación. Sin embargo, la especie se encuentra En Peligro con un área de ocupación de 28 km². Los sitios están contiguos a campos de cultivo, asentamientos humanos, incendios forestales, entre otros. El área de distribución potencial estimada con variables climáticas fue de 160.051 km2, los sitios con probabilidades de uno fueron validados en campo, pero no se encontró la especie.
Conclusiones: Lobelia villaregalis se encuentra en alto riesgo, se requieren acciones urgentes in situ y ex situ para su conservación.
Earthquake Detection with tinyML
Authors: Clements Timothy 
Published: May 2023

Abstract
Earthquake detection is the critical first step in earthquake early warning (EEW) systems. For robust EEW systems, detection accuracy, detection latency, and sensor density are critical to providing real-time earthquake alerts. Traditional EEW systems use fixed sensor networks or, more recently, networks of mobile phones equipped with microelectromechanical systems (MEMS) accelerometers. Internet of things edge devices, with built-in tiny machine learning (tinyML) capable microcontrollers, and always-on, internet-connected, stationary MEMS accelerometers provide the opportunity to deploy ML-based earthquake detection and warning using a single-station approach at a global scale. Here, I test and evaluate tinyML deep learning algorithms for earthquake detection on a microcontroller. I show that the tinyML earthquake detection models can generalize to earthquakes outside the training set.
Development Of Educational Crossword Puzzle Games In Arabic Vocabulary Learning For Madrasah Aliyah Students
Authors: Maskanah Siti Naharul , Nugrawiyati Jepri , Qomariyah Lailatul , Nafi'i Wildan , Dahlina Dahlina , Ibrahim Faishol Mahmud Adam 
Published: May 2023

This research examined the production of an educational crossword puzzle game used to facilitate Arabic vocabulary learning in Madrasah Aliyah. Using the Research and Development Approach by Borg and Gall, the authors used 4 stages to produce the product: exploration, product development, testing, and finalization. After analyzing the data using methods, the results show a score of 5 (very good category) and validated media experts with a score of 4.8. (Very good category), and limited trials with a score of 4.4 (very good category) and field trials with a score of 4.5 (good category). Further research is needed to expand this vocabulary learning technique beyond this small dataset.
Analysis of Changes in the Sound of Arabic Loan Words in the Translation of Akidatul Awam by Syekh Ahmad Marzuki (Crowley's Theory Perspective)
Authors: Wemamah A-esah , Aulia Fahnida 
Published: May 2023

Arabic has considerable influence over the Indonesian language, namely in vocabulary or loan words. This study aims to identify various forms of sound changes that occur in loanwords in the translation of the text Akidatul Awam. Using qualitative descriptive analysis, the researcher examined the data to discern the Arabic loan words in the text that take on an Indonesian phoneme. The results found 80 borrowed words in the translation of Akidatul Awam with various forms of sound changes in Crowley's theory; namely sound attenuation, sound reinforcement and sound addition. This research is expected to be able to increase knowledge in the field of linguistics, and assist language users in choosing and distinguishing loan words that are standard in Indonesian.
Use of Synonymous in The Qur'an (Semantic Analysis Study)
Authors: Al Sayyid Abdul Rahman , Habibi Muhammad Yusuf , Arief Ahmad Fahmy , Husin Saifudin Ahmad 
Published: May 2023

In the use of language, sometimes we find a difference between one speech and another speech with expressions that have one meaning. This phenomenon is also called by linguists with synonyms. Synonyms are two words that have one or more meanings, such as "death" and "died". This research aims to: 1. know the analysis of the word forms that are synonymous in Surah Al-Baqarah, 2. Analyze the meaning of rich words that are synonymous in Surah Al-Baqarah. The type of research used in this research is literature research with a qualitative approach. The primary data used are verses containing synonymous words in surah Al-Baqarah. And this research uses content analysis with the krippendorf data analysis model. The results of this research are: there are three forms of synonymous words which include: 1. synonyms inletter form , 2. synonyms in formname, and synonyms in the formfi'il. Adapum means 1. for synonyms inletter formamong them said "from"can meanli ibtida ghayyah (to begin the purpose), li tab'idh (part),liziyadatil taukid(for amplifier), while the word "on " can meanthat of (Because), min (from) 2. Tosynonyms in formnameamong them the words "the other daywhich is used to mention the end of world life, while the wordDoomsdayused for the mention of after the end of life in the world, and 3. Forsynonyms in formfi'il for example saidcreationwhich is used for the creation from nothing to exist, while the wordmake used from there then made into something new. In this study there is something new in that the division of synonym forms is different from the usual types of synonyms, namely: the synonym form consists of isim, fi'il, and letters while the synonym type consists ofat-taraduf al kamil, syibhut taraduf, at-taqaruf ad-dalali, at-tafawuf (fil 'umum, fil special, fil quwwah, Fil malamih)