bluuebunny/crossref_metadata_2025_split huggingface dataset:
Satisfaction with medication in older adult patients with chronic respiratory diseases: a multicenter cross-sectional observational study
Authors: Wu Jiankang , Meng Weiwei , Zeng Huihui , Ma Yiming , Chen Yan 
Published: August 2023

PurposeTo gain insight into medication satisfaction and factors associated with chronic respiratory disease, particularly chronic obstructive pulmonary disease (COPD) in older adults, focusing on public health issues and improving the health of the older adult population.MethodsThis cross-sectional study was conducted from October 2022 to November 2022 in 24 hospitals in different regions of Hunan Province, China. Older adult patient treatment satisfaction was assessed using the Treatment Satisfaction Questionnaire for Medication version II. Multiple regression analysis was used to identify factors independently associated with patient treatment satisfaction.ResultsOnly 15.9% of all patients scored above 80 in the effectiveness domain, while 11.6 and 16.5% scored above 80 in the convenience and global satisfaction domains, respectively, while 17.3% reported having side effects. Interstitial lung disease was associated with lower drug satisfaction than other disorders (p &lt; 0.05). Multifactorial regression analysis showed that age, education background, profession, and smoking status were independently associated with satisfaction among patients with chronic respiratory diseases (p &lt; 0.05). Education background, profession, CAT score, number of acute exacerbations, duration of home oxygenation and duration of home ventilator use were independently associated with satisfaction in patients with COPD (p &lt; 0.05).ConclusionLow satisfaction with chronic respiratory drug therapy was associated with age, education background, profession and smoking status. Satisfaction was lower for patients with interstitial lung disease. For COPD, CAT score, education background, profession, number of acute exacerbations, home oxygen and ventilator use influence satisfaction. Clinicians can identify appropriate patients and communicate effectively with them throughout treatment and follow-up, vigorously promote smoking cessation and home oxygen therapy, increase medication satisfaction, especially among older adults, and in turn improve public health and the quality of life of older adults.
The effect of a community-based group intervention on chronic disease self-management in a vulnerable population
Authors: Korenhof Sophie A. , Rouwet Ellen V. , Elstgeest Liset E. M. , Fierloos Irene N. , Tan Siok Swan , Pisano-Gonzalez Marta M. , Boone An L. D. , Pers Yves-Marie , Pilotto Alberto , López-Ventoso Mónica , Diez Valcarce Isabel , Zhang Xuxi ,   EFFICHRONIC Consortium, Raat Hein 
Published: August 2023

IntroductionChronic non-communicable diseases (NCDs) are predominantly related to modifiable health behaviors and account for 74% of global deaths at present. Behavior modification through self-management is a strategy to prevent NCDs. Chronic Disease Self-Management Programs (CDSMPs) have demonstrated improvements in health behaviors, health status, and use of healthcare.ObjectiveWe evaluated the effects of a 6-week CDSMP on self-efficacy, health behaviors, mental health, health-related quality of life (HR-QoL), and health responsibilities among vulnerable populations with chronic disease in Europe.MethodsA prospective cohort study with a 6-month pre-post single-group design was conducted in five European countries. The intervention targeted adults with chronic conditions and low socioeconomic status, as well as their caregivers. The intervention was a 6-week community-based CDSMP in a group setting. Outcomes were measured per self-report questionnaire at baseline and 6-month follow-up: self-efficacy, health behaviors, mental health, HR-QoL, and health responsibilities.ResultsOf 1,844 participants, 1,248 (67.7%) completed follow-up and attended ≥4 sessions. For the chronic condition group, the following outcome measures at follow-up significantly improved compared with baseline (all P &lt; 0.002): self-efficacy (SEMCD-6 6.7 vs. 6.4), mental health (PHQ-8 6.3 vs. 7.0), HR-QoL (SF-12 PCS 42.3 vs. 40.2, SF-12 MCS 42.8 vs. 41.4), health utility (EQ-5D-5L 0.88 vs. 0.86), self-rated health (EQ-5D-5L 67.2 vs. 63.9), communication with healthcare providers (2.28 vs. 2.11), understanding information (3.10 vs. 3.02), number of doctor visits (3.61 vs. 4.97), accident and emergency department visits (0.25 vs. 0.48), total nights in a hospital (0.65 vs. 1.13), and perceived medical errors (19.6 vs. 28.7%). No significant changes were detected in dietary habits, physical activity, substance use, and sleep and fatigue. For caregivers without a chronic condition, only doctor visits significantly decreased (1.54 vs. 2.25, P &lt; 0.001).DiscussionThis CDSMP was associated with improvement in self-efficacy, depression, HR-QoL, and health responsibilities over 6 months in a diverse European population with a chronic condition. However, additional interventions targeting lifestyle risk factors are needed to improve health outcomes.
Clinical and functional status of patients with severe COVID-19 pneumonia: an observational study at 2–3 months following discharge
Authors: Castillo Sánchez Inmaculada , Camarasa Julia Tárrega , Barbeta Sánchez Enric , Oliveira Vinicius Rosa 
Published: August 2023

IntroductionCritically ill COVID-19 patients present long-term sequelae that affect their everyday life. This study aimed to describe the clinical and functional status of patients with severe COVID-19 pneumonia at 2–3 months post discharge from a Spanish critical care unit.MethodsWe collected retrospective data from 58 patients admitted to the critical care unit with diagnosis of severe respiratory failure due to COVID-19. Only patients who required invasive (IMV) or noninvasive ventilation (NIV) during their hospital stay were included. The following data were collected 2–3 months after hospital discharge: respiratory signs and symptoms, lung ultrasound (LUS) and diaphragm ultrasound images, blood test analysis, lung function parameters (spirometry and DLCO), exercise capacity (6 min walk test and sit-to-stand test), level of physical activity and health-related quality of life.ResultsWe found clinical symptoms and lung structural alterations in LUS images of 26 patients (48.1%). Those presenting LUS abnormalities had longer length of stay in hospital (p = 0.026), functional alterations in spirometry (p &lt; 0.01) and decreased diaphragm excursion (p = 0.029). No significant alterations were observed in blood test analysis, exercise capacity, level of physical activity and health-related quality of life.ConclusionsA significant part of the patients admitted to a critical care unit continue to present clinical symptoms, pulmonary morphological abnormalities, and lung function alterations 2–3 months post discharge. This study corroborates that assessing the functional status of the survivors is essential to monitor the evolution of pulmonary sequelae.
The effect of Iran’s health sector evolution plan on hospitals performance indicators: an interrupted time series analysis
Authors: Soltani Shahin , Rezaei Satar , Kazemi-Karyani Ali , Azimi Jila , Jalili Faramarz , Roshani Bahman , Najafi Farid , Bagheri Parnia , Salimi Yahya 
Published: August 2023

BackgroundThe Health Sector Evolution Plan (HSEP) was set up in Iran’s health system to respond to some of the main problems in hospitals and other health sectors. We aimed to compare the effect of the HSEP on teaching hospital performance before and after the implementation of the HSEP through the interrupted time series (ITS) analysis.MethodsWith a cross-sectional design, data collection was performed in 17 teaching hospitals affiliated with the Kermanshah University of Medical Sciences (KUMS). We used the existing data on three indicators of hospitalization rate (per 10,000 population), Emergency Department Visits (EDVs) (per 10,000 population), and in-hospital mortality (per 10,000 population). The monthly data from 2009 to 2019 was analyzed by the ITS method 60 months before and 61 months after the HSEP.ResultsWe found a non-statistically significant decrease in the monthly trend of hospitalization rate relative to the period before the HSEP implementation (−0.084 per 10,000 population [95%CI: −0.269, 0.101](. There was a statistically significant increase in the monthly trend of EDVs rate compared to before the HSEP implementation (1.07 per 10,000 population [95%CI: 0.14, 2.01]). Also, a significant decrease in the monthly trend of in-hospital mortality compared to before the HSEP implementation [−0.003 per 10,000 population (95%CI: −0.006, −0.001)] was observed.ConclusionOur study demonstrated a significant increasing and decreasing trend for EDVs and in-hospital mortality following the HSEP implementation, respectively. Regarding the increase in hospitalization rate and EDVs after the implementation of HESP, it seems that there is a need to increase investment in healthcare and improve healthcare infrastructure, human resources-related indicators, and the quality of healthcare.
Automated segmentation and labeling of subcutaneous mouse implants at 14.1T
Authors: Adda Julien , Bioley Gilles , Van De Ville Dimitri , Cudalbu Cristina , Preti Maria Giulia , Gninenko Nicolas 
Published: August 2023

Magnetic resonance imaging (MRI) is a valuable tool for studying subcutaneous implants in rodents, providing non-invasive insight into biomaterial conformability and longitudinal characterization. However, considerable variability in existing image analysis techniques, manual segmentation and labeling, as well as the lack of reference atlases as opposed to brain imaging, all render the manual implant segmentation task tedious and extremely time-consuming. To this end, the development of automated and robust segmentation pipelines is a necessary addition to the tools available in rodent imaging research. In this work, we presented and compared commonly used image processing contrast-based segmentation approaches—namely, Canny edge detection, Otsu’s single and multi-threshold methods, and a combination of the latter with morphological operators—with more recently introduced convolutional neural network (CNN-) based models, such as the U-Net and nnU-Net (“no-new-net”). These fully automated end-to-end state-of-the-art neural architectures have shown great promise in online segmentation challenges. We adapted them to the implant segmentation task in mice MRI, with both 2D and 3D implementations. Our results demonstrated the superiority of the 3D nnU-Net model, which is able to robustly segment the implants with an average Dice accuracy of 0.915, and an acceptable absolute volume prediction error of 5.74%. Additionally, we provide researchers in the field with an automated segmentation pipeline in Python, leveraging these CNN-based implementations, and allowing to drastically reduce the manual labeling time from approximately 90 min to less than 5 min (292.959 s ± 6.49 s, N = 30 predictions). The latter addresses the bottleneck of constrained animal experimental time in pre-clinical rodent research.
Ac-Susceptibility Studies of the Energy Barrier to Magnetization Reversal in Frozen Magnetic Nanofluids of Different Concentrations
Authors: Botez Cristian E. , Price Alex D. 
Published: August 2023

We used ac-susceptibility to measure the blocking temperature, TB, and energy barrier to the magnetization reversal, EB, of nanomagnetic fluids of different concentrations, c. We collected data on five samples synthesized by dispersing Fe3O4 nanoparticles of average diameter ⟨D⟩ = 8 nm in different volumes of carrier fluid (hexane). We found that TB increases with the increase in c, a behavior predicted by the Dormann–Bessais–Fiorani (DBF) theory. In addition, our observed TB vs. c dependence is excellently described by a power law TB = A∙cγ, with A = 64 K and γ = 0.056. Our data also show that a Néel–Brown activation law τT=τ0exp⁡EBkBT describes the superspin dynamics in the most diluted sample, whereas an additional energy barrier term, Ead, is needed at higher concentrations, according to the DBF model: τT=τrexp⁡EB+EadkBT. We found EB/kB = 366 K and additional energy barriers Ead/kB that increase linearly with the common logarithm of the volume concentration, from 138 K at c = 8.3 × 10−4% to 745 K at c = 4 × 10−2%. These results add to our understanding of the contributions by different factors to the superspin dynamics. In addition, the quantitative relations that we established between the TB, Ead, and c support the current efforts towards the rational design of functional nanomaterials.
Mental Health of People with Intellectual Disabilities Living in Residential Care before, during, and after Lockdown
Authors: Gil-Llario María Dolores , Díaz-Rodríguez Irene , Fernández-García Olga , Estruch-García Verónica , Bisquert-Bover Mar , Ballester-Arnal Rafael 
Published: August 2023

Background: The impact of the COVID-19 on the well-being of people with intellectual disabilities (PID) has been little studied. Methods: We analyzed its impact with a cohort study quantitatively analyzing anxiety, depression, organic symptoms, quality of life, and support needs in 24 PID, aged 19–74 years (x¯ 40, σ = 13.09), living in a residential center, before, during, and after the pandemic. Results: Their mental health improved unexpectedly at the onset of the lockdown although there was an increase in organic symptoms. But, with the progress of the lockdown, their mental health deteriorated drastically. On the contrary, as expected, their quality of life and support needs worsened from the beginning of the lockdown until the country returned to normality, a time when there was a general recovery, without reaching pre-pandemic levels. These results show that the mental health of PID was affected differently to that of people without intellectual disabilities.
Molecular Characterization and Response of Silver Carp (Hypophthalmichthys molitrix) GLUT1 under Hypoxia Stress
Authors: Zhang Zewen , Li Xiaohui , Zou Guiwei , Liang Hongwei 
Published: August 2023

As an important freshwater species with economic and ecological benefits, silver carp (Hypophthalmichthys molitrix) exhibits poor tolerance to hypoxia. Glucose transporters (GLUTs) are core membrane proteins that transport glucose to tissues and regulate essential life activities. Its expression is regulated by HIF-1α and cells in hypoxic conditions to maintain energy demand through GLUTs inducing enhanced glucose transport. We cloned H. molitrix glut1 (SLC2A1) and analyzed its sequence using bioinformatics tools. The glut1 cDNA was 2104 base pairs long and encoded a 490 amino acid protein. Phylogenetic analysis revealed that sliver carp glut1 is evolutionarily conserved and exhibited the highest sequence similarity with Ctenopharyngodon idella glut1. Glut1 expression was the highest and lowest in the gills and liver, respectively. Hypoxic stress significantly increased glut1 expression in the brain (p < 0.05); in the gills, it was the highest and lowest in the semi-asphyxia and asphyxia groups, respectively; in the liver, it was significantly higher under hypoxia than that of the normoxia group; and in the heart, it was significantly higher in the floating head, semi-asphyxia, and asphyxia groups than in the normoxia group (p < 0.05). The proposed mechanism may thus provide the basis for elucidating the molecular basis of silver carp’s hypoxia stress response mediated by glut1.
Systematic Assessment of Hebius beddomei (Günther, 1864) (Serpentes: Colubridae: Natricinae) with Description of a New Genus and a New Allied Species from the Western Ghats, India
Authors: Patel Harshil , Thackeray Tejas , Campbell Patrick D. , Mirza Zeeshan A. 
Published: August 2023

Hebius beddomei (Günther, 1864) is an endemic natricine colubrid snake species from the biodiverse Western Ghats, India. A recent molecular phylogeny provided evidence for the paraphyly of the genus Hebius, with Hebius beddomei recovered as sister to a clade containing Fowlea and Atretium. Freshly collected specimens and existing museum material allowed us to elucidate the generic status of the species and identify two distinct populations, one of which is described as a new species. A new genus, Sahyadriophis gen. nov., is proposed to accommodate Sahyadriophis beddomei gen. et. comb. nov., and Sahyadriophis uttaraghati gen. et. sp. nov. is described as a new species from the northern part of the range. The discovery of a new Oligocene divergent lineage, Sahyadriophis gen. nov., highlights the role of the Western Ghats as a source of relic lineages.
DAMPAK POLITIK IDENTITAS PADA PEMILIHAN UMUM 2024 MENDATANG
Authors: Perdana Andre Pebrian 
Published: August 2023

Politik identitas akan terus hadir dalam narasi politik Indonesia menuju pemilihan presiden 2024 mendatang. Karena kondisi mental dan karakter masyarakat Indonesia belum terlepas dari sentimen primordialisme dan sektarianisme yang masih kuat mengakar dalam budaya masyarakat Indonesia sekalipun sudah hidup di era demokratisasi terbuka dan era digitalisasi modern. istilah politik identitas sudah lama dikontruksi sebagai narasi politik oleh kolompok elit politik tertentu di Indonesia sebagai wacana instrumen untuk menggambarkan rasa kebencian dan ketakutan kalah pada pihak lawan politiknya agar bisa menurunkan citra dan menyudutkan pigur tertentu yang biasanya dinilai kuat dan berpotensi menang, bisa mengalahkan lawan lainnya sehingga perlu disudutkan dengan narasi tidak nasionalis dan intoleran. Politik Identitas pada dasarnya adalah situasi dan cara berpolitik yang mempersatukan kelompok karena adanya rasa ketidakadilan dan ketidakpuasan yang didasari oleh persamaan latar belakang golongan, contohnya suku, ras, agama, dan jender. Identitas bukan hanya soal sosiologis tetapi juga bisa masuk ke ranah politik. politik identitas dapat berpengaruh baik dan buruk dalam republik yang berbhinneka ini.

Kata Kunci: Dampak, Politik Identitas, Pemilihan Umum
PENGEMBANGAN PARIWISATA BUDAYA DI KOTA BANDUNG DALAM SUDUT PANDANG IMPLEMENTASI KERJA SAMA PEMERINTAH DENGAN BADAN USAHA
Authors: Asmariadi Adi 
Published: August 2023

Kota Bandung merupakan salah satu kota destinasi wisata di Indonesia yang memiliki beragam potensi wisata. Namun saat ini, pariwisata yang berkembang di Kota Bandung lebih mengarah pada pariwisata kreatif dan kontemporer, wisata berbasis budaya sendiri tidak banyak muncul dan dikenal dari kota ini. Penelitian ini dilakukan dengan inisiasi dari permasalahan tersebut, dengan tujuan untuk memahami kondisi pariwisata budaya di Kota Bandung. Pendekatan kualitatif dilakukan dengan metode wawancara mendalam. Penelusuran pustaka terkait skema Kerja sama Pemerintah-Swasta (KPS) juga dilakukan dengan tujuan untuk menyandingkan kondisi yang terjadi dengan solusi yang dapat diberikan oleh skema KPS. Hasil penggalian diperoleh bahwa kondisi pariwisata budaya di Kota Bandung kalah terkenal dengan pariwisata kontemporer. Pemerintah Kota Bandung memiliki andil yang besar terhadap kondisi yang terjadi tersebut. Diketahui bahwa pemerintah mengalami berbagai kendala dalam pengembangan pariwisata budaya di kota tersebut. Berdasarkan penyandingan dengan konsep KPS, maka pola-pola dalam KPS dapat menjadi salah satu solusi dalam mengatasi kendala-kendala yang dihadapi oleh pemerintah dalam pembangunan pariwisata budaya di Kota Bandung.
ANALISIS POTENSI DAN PROYEKSI PEREKONOMIAN PROVINSI LAMPUNG TAHUN 2023
Authors: Dardanila Miraya 
Published: August 2023

Sebagai upaya peningkatan daya saing daerah khususnya Provinsi Lampung, maka peningkatan pertumbuhan ekonomi menjadi hal yang dibutuhkan. Pertumbuhan ekonomi memiliki peran untuk memajukan perekonomian daerah. Penelitian ini bertujuan mengetahui isu trategis perekonomian Provinsi Lampung, sektor yang potensial mendukung ekonomi Lampung dan proyeksi laju pertumbuhan ekonomi Provinsi Lampung Tahun 2023. Penelitian ini berbentuk deskriptif kuantitatif, pada jenis data menggunakan data sekunder yang berbentuk data gabungan tuntun waktu (time series) dari tahun 2017-2021. Berdasarkan hasil penelitian, isu strategis pertumbuhan ekonomi Provinsi Lampung masih didominasi oleh sektor pertanian yang rentan terhadap fluktuasi harga komoditas. Sedangkan sektor-sektor ekonomi yang berpotensi sebagai sektor unggulan dalam mempercepat pertumbuhan ekonomi Provinsi Lampung adalah (1) pertanian (2) transportasi dan pergudangan (3) pengadaan air, pengelolaan sampah dan lainnya. Proyeksi ekonomi Provinsi Lampung pada tahun 2023 didominasi oleh (1) pertanian (2) industri pengolahan (3) perdagangan.
Strategi Mitigasi Bencana Tsunami Di Desa Kema Satu Kabupaten Minahasa Utara
Authors: Tanauma Adey , Pasau Guntur , Tamuntuan Gerald 
Published: August 2023

AbstractKema Satu Village is one of the villages in North Minahasa Regency. The area is facing directly with the Molucca Sea which is the source of the highest intensity of earthquake in Indonesia. Based on the results of the survey and situation analysis, it is known that a group of people in this village do not understand things related to tsunami disaster risk reduction. Therefore, a community partnership program (Program Kemitraan Masyarakat) has been implemented in the form of socializing the tsunami disaster mitigation strategy in Kema Satu village. The methods that have been used are counseling and simulation. The discussion and evaluation conducted at the end of the activity revealed that the program implemented had increased the public's insight and knowledge about the earthquake and tsunami potential in the area. The participating communities have also understood the ways that need to be prepared or implemented in the context of tsunami disaster mitigation.Keywords: Mitigation; tsunami; earthquake AbstrakDesa Kema Satu adalah salah desa di Kabupaten Minahasa Utara dimana wilayahnya ke arah timur berhadapan langsung dengan Laut Maluku yang merupakan daerah sumber gempa bumi dengan intensitas tertinggi di Indonesia. Berdasarkan hasil survey dan analisis situasi diketahui bahwa kelompok masyarakat di desa ini kurang memahami hal-hal terkait pengurangan resiko bencana tsunami. Oleh karena itu telah dilaksanakan program kemitraan masyarakat dalam bentuk sosialisasi strategi mitigasi bencana tsunami di desa tersebut. Metode yang digunakan adalah penyuluhan dan simulasi sederhana. Dari diskusi dan evaluasi yang dilakukan pada akhir kegiatan diketahui bahwa program yang dilaksanakan telah meningkatkan wawasan dan pengetahuan masyarakat tentang gempa dan potensi tsunami di daerah tersebut, serta cara-cara yang perlu dipersiapkan ataupun dilaksanakan dalam rangka mitigasi bencana tsunami.Kata kunci: Mitigasi; tsunami; gempa