bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chemical Profiles and Cytotoxic Activities of Essential Oils from Six Species ofBaccharisSubgenusCoridifoliae(Asteraceae)
Authors: Paes de Almeida Valter , Tolouei Sara Emília Lima , Minteguiaga Manuel , Chaves Douglas Siqueira de Almeida , Heiden Gustavo , Khan Shabana Iqrar , Trott John , Wang Mei , Dellacassa Eduardo , Raman Vijayasankar , Farago Paulo Vitor , Khan Ikhlas Ahmed , Gasparotto Junior Arquimedes , Manfron Jane 
Published: August 2023

AbstractSeveralBaccharisspecies are popularly known in traditional medicine as“carquejas”,“vassouras”, “ervas‐santas” and “mio‐mios”, and are used as anti‐inflammatories, digestives, and diuretics. This study aimed to investigate the chemical compositions and cytotoxic activities of essential oils (EOs) of sixBaccharisspecies belonging to subgenusCoridifoliae, namelyB. albilanosa,B. coridifolia,B. erigeroides,B. napaea,B. ochracea, andB. pluricapitulata. GC/MS analyses of the EOs showed that the oxygenated sesquiterpenes spathulenol (7.32–38.22 %) and caryophyllene oxide (10.83–16.75 %) were the major components for all the species. The EOs of almost all species were cytotoxic against cancer (BT‐549, KB, SK‐MEL and SK‐OV‐3) and normal kidney (VERO and LLC‐PK1) cell lines, whereasB. erigeroidesEO showed cytotoxicity only against LLC‐PK1. This article augments the current knowledge about the chemical‐biological properties ofBaccharissubgenusCoridifoliaeand discusses the therapeutic potentials of these economically unexploited plants.
Exploring the Therapeutic Properties of Alga‐Based Silver Nanoparticles: Anticancer, Antibacterial, and Free Radical Scavenging Capabilities
Authors: Khan Amir Hamza , Hassan Said , Aamir Muhammad , Khan Muhammad Waseem , Haq Fazal , Hayat Junaid , Rizwan Muhammad , Ullah Amin , Ullah Izzat , Zengin Gokhan , Farid Arshad 
Published: August 2023

AbstractThe current study was designed to evaluate the antioxidant, anticancer and antimicrobial activities of silver nanoparticles (AgNPs) biosynthesized by Spirulina platensis extract. The biosynthesized silver nanoparticles were characterized using Fourier transform infrared (FT‐IR) analysis, scanning electron microscopy (SEM), transmission electron microscopy (TEM) and X‐ray diffraction (XRD) analysis. The antioxidant activity of the biosynthesized AgNPs were determined via DPPH radical scavenging assay while its anticancer activity was determined using the MTT assay. The antimicrobial activity of the biosynthesized AgNPs were analyzed by disc diffusion method. Spirulina platensis acts as a reducing and capping agent. The efficacy of silver nanoparticles (AgNPs) in inhibiting the growth of Gram‐negative bacteria, specifically Acetobacter, Klebsiella, Proteus vulgaris, and Pseudomonas aeruginosa, was assessed by the utilisation of the diffusion method. The study aimed to evaluate the efficacy of biosynthesized silver nanoparticles (AgNPs) against many strains of Pseudomonas aeruginosa bacteria. The findings of the study revealed that when administered in doses of 50 μl, 75 μl, and 100 μl, the largest observed zone of inhibition corresponded to measurements of 10.5 mm, 14 mm, and 16 mm, respectively. A zone of inhibition with dimensions of 8 mm, 10.5 mm, and 12 mm was detected during testing against Acetobacter at concentrations of 50 μl, 75 μl, and 100 μl, respectively. The findings also indicate that there is a positive correlation between the concentration of AgNP and the DPPH scavenging ability of silver nanoparticles. The percentage of inhibition observed at concentrations of 500 μg/ml, 400 μg/ml, 300 μg/ml, 200 μg/ml, and 100 μg/ml were recorded as 80±1.98, 61±1.98, 52±1.5, 42±1.99, and 36±1.97, respectively. In addition, it was observed that the silver nanoparticles exhibited the greatest antioxidant activity at a concentration of 500 g/ml, with a measured value of 80.89±1.99. The IC‐50 values, representing the inhibitory concentration required to achieve 50 % inhibition, were found to be 8.16, 19.15, 30.14, 41.13, and 63.11 at inhibition levels of 36±1.97, 42±1.99, 52±1.5, 61±1.98, and 80±1.98, respectively.
Difficulty in diagnosing peritonitis caused by multidrug‐resistant tuberculosis
Authors: Aoyama Sayaka , Yamashita Shun , Ishizuka Kosuke , Katsukura Shinichi , Matsuura Hiroki , Kato Mikiro 
Published: August 2023

Key Clinical MessageThe low sensitivity of ascites culture for acid‐fast bacilli necessitates a peritoneal biopsy when tuberculous peritonitis is suspected. Findings in the peritoneum on computed tomography may prompt suspicion of tuberculous peritonitis.AbstractA 47‐year‐old Nigerian man presented with fever, abdominal distention, and weight loss. Abdominal computed tomography revealed massive ascites and peritoneal thickening. Despite failing to culture acid‐fast bacilli from ascites, histological examination and culture of peritoneum revealed multidrug‐resistant tuberculosis peritonitis. Peritoneal biopsy is mandatory when tuberculosis peritonitis is suspected.
Design and study of a novel ammonia‐based CO2 capture process with bipolar membrane electrodialysis
Authors: Song Zhengyuan , Sun Guogang , Wang Zetao , Yuan Shiwei , Xi Chenhao 
Published: August 2023

AbstractAqueous ammonia is a promising absorbent in the field of post combustion CO2 capture. However, the high volatilization of NH3 results in a high energy requirement, as well as solid precipitation during the CO2 regeneration process. A novel process was designed to reduce energy consumption and solve the problem. The bipolar membrane electrodialysis (EDBM) unit and CO2 regeneration reactor were taken as the regeneration part. In the novel process, the bubble in the EDBM unit would be eliminated, and the regeneration of CO2 and aqueous ammonia would be operated separately, which significantly reduced energy consumption and avoided the risk of precipitation during regeneration. According to the simulation and calculation results, the CO2 regeneration energy consumption of the novel process using H2SO4 for CO2 regeneration is 39.0% lower than that of the conventional ammonia‐based process, which shows good energy saving potential. Moreover, the novel process will be more competitive as membrane technology develops.
A deep graph convolutional network model of NOx emission prediction for coal‐fired boiler
Authors: Wang Yingnan , Zhao Chunhui 
Published: August 2023

AbstractTo deal with environmental problems caused by NOx production in thermal plants, it is imperative to establish a reliable model to predict NOx concentration in the combustion process. NOx formation in a coal‐fired boiler is complex, and many variables affect NOx emissions. The effective information fusion of these variables can improve the accuracy of NOx concentration prediction. However, the existing NOx prediction algorithms based on thermal parameters rarely consider the mechanical knowledge of the boiler operation, and it is not easy to incorporate the topological information of production into modelling. Therefore, a graph convolutional network is proposed for NOx emission prediction. First, the key variables affecting NOx generation are selected according to the knowledge and the random forest‐based variable importance. Then, the model structure is designed by exploring the topological information among thermal variables to capture the complex spatial dependence. The model inputs are constructed by coding different operation variables, and the adjacency matrix is generated according to the correlation information between variables, which can fuse data information and reduce redundancy. On this basis, the prediction model of NOx concentration is established. Historical data from a 660 MW coal‐fired boiler are used in the experiment. The prediction results show that the proposed model can effectively fuse the information of characteristic variables and fully exploit the non‐linear mapping relationship between process variables and NOx emission. When compared with three typical models in NOx modelling, the proposed model has better performance with a determination coefficient of 0.906.
Entropy and improved k‐nearest neighbor search based under‐sampling (ENU) method to handle class overlap in imbalanced datasets
Authors: Kumar Anil , Singh Dinesh , Yadav Rama Shankar 
Published: August 2023

SummaryMany real‐world application datasets such as medical diagnostics, fraud detection, biological classification, risk analysis and so forth are facing class imbalance and overlapping problems. It seriously affects the learning of the classification model on these datasets because minority instances are not visible to the learner in the overlapped region and the performance of learners is biased towards the majority. Undersampling‐based methods are the most commonly used techniques to handle the above‐mentioned problems. The major problem with these methods is excessive elimination and information loss, that is, unable to retain potential informative majority instances. We propose a novel entropy and neighborhood‐based undersampling (ENU) that removed only those majority instances from the overlapped region which are having less informativeness (entropy) score than the threshold entropy. Most of such existing methods improved sensitivity scores significantly but not in many other performance contexts. ENU first computes entropy and threshold score for majority instances and, a local density‐based improved KNN search is used to identify overlapped majority instances. To tackle the problem effectively ENU defined four improved KNN‐based procedures (ENUB, ENUT, ENUC, and ENUR) for effective undersampling. ENU outperformed in sensitivity, G‐mean, and F1‐score average ranking with reduced information loss as compared to the existing state‐of‐the‐art methods.
High Entropy Pr‐Doped Hollow NiFeP Nanoflowers Inlaid on N‐rGO for Efficient and Durable Electrodes for Lithium‐Ion Batteries and Direct Borohydride Fuel Cells
Authors: Basumatary Padmini , Hyeok Choi Ji , Emin Kilic Mehmet , Konwar Dimpul , Soo Yoon Young 
Published: August 2023

AbstractThe selection and design of new electrode materials for energy conversion and storage are critical for improved performance, cost reduction, and mass manufacturing. A bifunctional anode with high catalytic activity and extended cycle stability is crucial for rechargeable lithium‐ion batteries and direct borohydride fuel cells. Herein, a high entropy novel three‐dimensional structured electrode with Pr‐doped hollow NiFeP nanoflowers inlaid on N‐rGO was prepared via a simple hydrothermal and self‐assembly process. For optimization of Pr content, three (0.1, 0.5, and 0.8) different doping ratios were investigated. A lithium‐ion battery assembled with NiPr0.5FeP/N‐rGO electrode achieved an outstanding specific capacity of 1.61 Ah g−1 at 0.2 A g−1 after 100 cycles with 99.3 % Coulombic efficiencies. A prolonged cycling stability of 1.02 Ah g−1 was maintained even after 1000 cycles at 0.5 A g−1. In addition, a full cell battery with NiPr0.5FeP/N‐rGO∥LCO (Lithium cobalt oxide) delivered a promising cycling performance of 0.52 Ah g−1 after 200 cycles at 0.15 A g−1. Subsequently, the NiPr0.5FeP/N‐rGO electrode in a direct borohydride fuel cell showed the highest peak power density of 93.70 mW cm−2 at 60 °C. Therefore, this work can be extended to develop advanced electrode for next‐generation energy storage and conversion systems.
Palladium‐Catalyzed [4+2] Cycloaddition of Vinyl Benzoxazinanones with 1,3‐Indanedione: Approach to Spiro‐Tetrahydroquinoline Scaffolds
Authors: Wei Qinglang , Tu Liang , Li Sen , Zheng Yongsheng , Liu Jikai 
Published: August 2023

AbstractA palladium catalyzed decarboxylative [4+2] cycloaddition of vinyl benzoxazinanones with 2‐arylidene indan‐1,3‐dione has been established, which afford a series of bioactive spiro‐tetrahydroquinolines (27 examples) in moderate to good yield (up to 87 %) with high diastereoselectivities. The synthetic utility of this reaction was demonstrated by gram‐scale synthesis. Compounds synthesized by this method potently inhibited proliferation in a panel of cancer cell lines. Particularly, the most potent compounds 3 ae, 3 ah, 3 aj and 3 fa displayed selective inhibition of MDA‐MB‐231 breast carcinoma cells with IC50 values of 1.292, 0.6118, 0.6558, 1.656 and 2.215 μM, respectively.
Base Promoted Synthesis of 4‐Quinolones Fused with Medium‐Sized Rings
Authors: Wang Mengdan , Ma Junying , Wang Junling , Lu Weiwei , Pan Bingli 
Published: August 2023

AbstractIn the presence of cesium carbonate, ynones bearing an ortho‐amino group reacted with cyclic β‐ketoesters through conjugated addition/carbon‐carbon σ‐bond cleavage/nucleophilic aromatic substitution tandem reaction to obtain 4‐quinolones fused with medium‐sized rings in good yields. This is the first example of synthesis of 4‐quinolones through base‐promoted insertion reactions of carbon‐carbon triple bonds into carbon‐carbon σ‐bonds. Notable features of this program are mild and transition‐metal‐free reaction conditions.
Analysis and design of a vertical sectored tank
Authors: Ferrer Gisbert Pablo Sebastián , Ferrer Gisbert Carlos Manuel , Ferrán Gozálvez José Javier , Redón Santafé Miguel , Torregrosa Soler Juan Bautista , Sánchez Romero Francisco Javier 
Published: August 2023

AbstractThis article describes the conceptual design and the structural analysis of a vertical cylindrical partitioned tank for an international chemical company. Vertical cylindrical tanks are commonly used in the chemical industry worldwide as vessels to contain liquids. Most of these plants have reduced area for the installation of the container tanks. Many of them need to renew their manufacturing process according to the new technologies and requirements. In addition, in some cases, the preparation of mixtures is carried out on small surfaces. All this factors led to the idea of designing a vertical sectorised tank, considering that alternative hydrostatic pressure cases can lead to eccentric loads on the upper surfaces. Therefore, bending stresses and compression and tension stresses will occur. A Finite Element Method calculation was performed to determine the wall thickness fulfilling the structural requirements for two distinguishing design alternatives. This article describes the particular models designed and the detailed FEM simulation and mechanical calculation carried out to determine the optimized solution of partitioned tanks with a diamond‐shaped inner bracing system that manages to meet all the structural, manufacturing, constructive and environmental needs with a target thickness of 12 mm.
Dynamic testing of a new integrated collector storage solar water heater (ICSSWH) according to standard ISO 9459‐5: Use of a numerical approach for long‐term prediction in different climatic conditions
Authors: Messaouda Anis , Hamdi Mohamed , Hazami Majdi , Guizani Amen Allah 
Published: August 2023

AbstractThis work analyzes the performance of a new Integrated Collector Storage Solar Water Heater (ICSSWH) by using Dynamic System Testing (DST) method according to Standard ISO 9459‐5. The long‐term performance study of the system in different climatic conditions has been achieved by a coupling model between DST results and a numerical approach based on the system transient behavior. Results of the experimental dynamic system evaluation showed that the total store heat capacity Cs, the useful collector surface Ac* and the storage tank heat losses coefficient Us are, respectively, 0.87 MJ/K, 1.21 m2 and 10 W/K. In Tunisian climatic conditions, the ICSSWH system allows covering until 79.3% from a typical family need for a daily consumption of 170 L. The results found allow optimizing the energy gain of the ICSSWH as well as selecting a specific load volume according to the location. Especially, investigations showed that in Stockholm and Riadh climatic conditions, the ICSSWH's solar fraction reached 27% and 83%, respectively, for a daily load volume of 250 L. More importantly, the experimental effort of DST identification can be minimized by coupling DST data with a robust numerical approach.
Investigation of the synergistic effect of red phosphorus and magnesium hydroxide on the thermal degradation behavior and flame resistance of the intumescent fire‐retardant polypropylene system
Authors: Thi Nhung Hac , Doanh Truong Cong , Dat Doan Tien , Oanh Ho Thi , Nguyen Ha Tran , Van Nguyen Tuyen , Tran Quang Vinh , Hoang Mai Ha 
Published: August 2023

AbstractHigh fire‐resistance polypropylene (PP) composites were prepared by using environment‐friendly flame retardants including expandable graphite (EG), red phosphorus (RP), and magnesium hydroxide (MH). Synergism between EG, RP, and MH on the thermo‐oxidation behavior and flame resistance of PP was found. The incorporation of MH and RP formed highly thermally stable mixtures of magnesium phosphates consisting of Mg3(PO4)2, Mg(PO3)2, and α‐Mg2P2O7 at both amorphous and crystalline phases in the burning process. The mixture not only covered the surface of burning materials but also could reinforce the char structure of the PP/EG composites, thereby significantly enhancing the condensed phase flame retardant mechanism of the composites. Mass ratios of the flame retardants were also optimized to obtain the composite with the highest flame retardant efficiency. The result revealed that the combination of EG, RP, and MH in PP at MH/RP mass ratio of 3/2 with only a total additive content of 18 wt.% could make its limiting oxygen index (LOI) increase from 16.8% to 27.2% and the UL‐94 rating was improved from none to V‐0. In addition, the mechanical properties of the composites were improved via the surface treatment of MH and RP with calcium stearate and silicone oil, respectively.
Promoting engagement in online learning beyond COVID‐19: Possible strategies and directions for future research
Authors: Hew Khe Foon , Huang Weijiao 
Published: August 2023

AbstractIn the aftermath of the global pandemic, online learning is now ubiquitous around the world. Yet, although online learning has become a common learning approach across the globe, it is still viewed as a weaker option than on‐campus face‐to‐face learning. Specifically, the lack of student engagement in online learning poses a persistent problem to many educators. In this article, we describe three key challenges of fully online learning: students being more easily distracted, students lacking self‐regulation skills and students feeling isolated. Next, we present three possible strategies to address these challenges: promoting active learning through the online flipped classroom model, promoting self‐regulation skills and reducing the sense of isolation through the use of chatbots. For each of the three strategies, we provide a description with relevant empirical studies based on our own work as well as previous work in the literature and discuss possible directions for further research.
Multishell diffusion MRI reveals whole‐brain white matter changes in HIV
Authors: Minosse Silvia , Picchi Eliseo , Conti Allegra , di Giuliano Francesca , di Ciò Francesco , Sarmati Loredana , Teti Elisabetta , de Santis Silvia , Andreoni Massimo , Floris Roberto , Guerrisi Maria , Garaci Francesco , Toschi Nicola 
Published: August 2023

AbstractDiffusion tensor imaging (DTI) and diffusion kurtosis imaging (DKI) have been previously used to explore white matter related to human immunodeficiency virus (HIV) infection. While DTI and DKI suffer from low specificity, the Combined Hindered and Restricted Model of Diffusion (CHARMED) provides additional microstructural specificity. We used these three models to evaluate microstructural differences between 35 HIV‐positive patients without neurological impairment and 20 healthy controls who underwent diffusion‐weighted imaging using three b‐values. While significant group effects were found in all diffusion metrics, CHARMED and DKI analyses uncovered wider involvement (80% vs. 20%) of all white matter tracts in HIV infection compared with DTI. In restricted fraction (FR) analysis, we found significant differences in the left corticospinal tract, middle cerebellar peduncle, right inferior cerebellar peduncle, right corticospinal tract, splenium of the corpus callosum, left superior cerebellar peduncle, left superior cerebellar peduncle, pontine crossing tract, left posterior limb of the internal capsule, and left/right medial lemniscus. These are involved in language, motor, equilibrium, behavior, and proprioception, supporting the functional integration that is frequently impaired in HIV‐positivity. Additionally, we employed a machine learning algorithm (XGBoost) to discriminate HIV‐positive patients from healthy controls using DTI and CHARMED metrics on an ROIwise basis, and unique contributions to this discrimination were examined using Shapley Explanation values. The CHARMED and DKI estimates produced the best performance. Our results suggest that biophysical multishell imaging, combining additional sensitivity and built‐in specificity, provides further information about the brain microstructural changes in multimodal areas involved in attentive, emotional and memory networks often impaired in HIV patients.
UndocuCare: Strategies for mental health services that affirm undocumented college students’ psychological needs
Authors: Nienhusser H. Kenny , Cadenas Germán A. , Sosa Raquel , Moreno Oswaldo 
Published: August 2023

AbstractThere are an estimated 427,000 undocumented college students enrolled in higher education. Undocumented college students encounter unique challenges associated with their precarious immigration status that impacts their psychological well‐being. In this article, we contextualize the mental health of undocumented college students and the role of college mental health services and professionals in supporting college students’ psychological well‐being. We end with recommendations and, in some cases, examples for campus mental health services, college counseling professionals, and counseling‐related preparation programs to develop policies and practices that affirm and support the mental health of undocumented college students.Practical TakeawaysUndocumented college students face a higher education landscape that is riddled with discriminatory public policies and college environments that largely neglect their specific needs and fail to promote their success.Immigration policies shape the well‐being of immigrant students by way of immigration status. For instance, college students with precarious immigration status (lacking access to permanent legal protections) have been found to have lower psychosocial well‐being compared to groups with more secure or permanent statuses (i.e., naturalized citizens).College mental health services are paramount in developing strategies and efforts that affirm the specific psychological needs of undocumented college students.We provide recommendations for higher education institutions in three areas: campus mental health services, college counseling professionals (developing cultural competency for mental health services with undocumented students, engaging in structural changes to affirm undocumented students’ mental health, holding broader campus initiatives to advocate for immigrant rights), and counseling‐related preparation programs.