bluuebunny/crossref_metadata_2025_split huggingface dataset:
“I am who I am”
Authors: Ting Su-Hie , Yeo Jiin-Yih , Jerome Collin , Ling Hsin-Nie 
Published: July 2023

AbstractThe study examined how LGBTQ individuals negotiate their identities in the Malaysian heteronormative society using the Discourse-Historical Approach. In-depth interviews were carried out with 13 LGBTQ individuals to find out the discursive strategies they used in describing the triggers for coming out, their experiences, and the reasons for their struggles. The analysis of the interview data showed that the participants used the “destiny” and “rights” arguments to counter the “legal”, “religious” and “traditional values” arguments used by heterosexuals to reject them. Referents and personal pronouns were selectively used by LGBTQ participants to present different perspectives, “us” versus “them” (heterosexuals), “I” and other LGBTQ individuals, and “I” versus “they” or “you” (other sexual orientations). The findings have implications that are relevant to mitigation of LGBTQ identities in contexts which have strong heteronormative norms due to legal, religion and traditional values.
Shouldering responsibility
Authors: Grundy Peter 
Published: July 2023

Abstract
This chapter explores my experience as a participant in the
Covid-19 Oxford vaccine trial and particularly the contrapuntal relationship between
the naïve event diary I kept and my increasingly careful reading of the Participant
Information Sheet (PIS). Adopting an autoethnographic approach, I describe the
gradual process by which I came to realize how naively I had understood my role and
how I then applied a pragmatic framework in re-evaluating the PIS as an exercise in
exoneration and the transfer of responsibility from the investigator to the
participant. While the PIS focuses on enumerating risks without considering the
false negative possibility that the trial might be successful and yet still fail to
identify a serious risk, my event diary shows how a volunteer’s sense of participant
integrity is undermined when this risk that dare not speak its name actually
occurs.
Risk discourse in the linguistic landscape
Authors: Syrjälä Väinö 
Published: July 2023

Abstract
Signs in the linguistic landscape (LL) can be used to both
inform the public and to regulate their actions – functions that are highly relevant
when communicating about risk. This chapter discusses the characteristics of the
risk discourse carried by the linguistic landscape, more specifically the safety
information signage found onboard metro carriages in Stockholm and Helsinki. The
analysis deals with both how such information is presented on the multimodal signs
and what kinds of risks and responsibilities are depicted as part of this
information. The results show that emplacement and the visual design, more
specifically the application of colours, are noteworthy characteristics of risk
discourse present in the LL. Few actual risks are spelled out in the signage and
even if the readers can be given responsibility to act in the face of risks, this
information can be worded in different ways. Considering interpersonal speech
functions, both direct commands and more ambivalent, passive statements can be
found, with some differences in practices between the two cities. Overall, the
situated nature of the safety information signage points to the role of place
semiotics in meaning making within risk discourse, thus highlighting the value of
considering the LL in order to gain a better understanding of risk
communication.
Culture and identity in critical remarks
Authors: Zbenovich Claudia , Larina Tatiana , Ozyumenko Vladimir 
Published: July 2023

Abstract
Awareness of cultural specificity in current classroom discourse is particularly important in an educational
setting that has become largely multicultural due to globalization, migration and academic mobility. Drawing on the intercultural
and cross-cultural pragmatics, and cultural studies, this paper explores the speech act of critical remark in Russian and Israeli
classroom settings, focusing on students’ view of its degree of conventionality and admissibility. Data were obtained from a
student survey questionnaire (undertaken between 2017-2019). Highlighting similarities and differences, we argue that both Russian
and Israeli classroom settings exhibit critical remark as not uncommon, though varying in acceptability. Findings show that
critical acts need not be limited to the merely conflictual, but may even be perceived positively, and may moreover exert varying
levels of illocutionary force and be interpreted differently by different cultural groups.
Mean and variance of the cardinality of particles in infinite true polyanalytic Ginibre processes via a coherent states quantization method
Authors: Mouayn Zouhaïr , Mahboubi Mohamed , Moize Othmane El 
Published: July 2023

Abstract
We discuss the mean and variance of the number ‘point-particles’

♯

D

R

inside a disk D

R
centered at the origin of the complex plane

C

and of radius R > 0 with respect to an infinite true polyanalytic process of index

m
∈

Z

+

by quantizing the phase space

C

via a set of generalized coherent states (CSs)

z
,
m

of the harmonic oscillator on

L

2

R

. By this procedure, the spectrum of the quantum observable representing the indicator function

χ

D

R

ofD

R
(viewed as a classical observable) allows to compute the mean value of

♯

D

R

. The variance of

♯

D

R

is obtained as a special eigenvalue of a quantum observable involving the auto-convolution of

χ

D

R

. By adopting a CSs quantization approach, we seek to identify classical observables on

C

,

whose quantum counterparts may encode the first cumulants of

♯

D

R

through spectral properties.
Preparation and characterization of PMMA/ZnO nanocomposites for antistatic and biomedical applications
Authors: Saied M A , Abdel Nour K N 
Published: July 2023

Abstract
Polymethyl methacrylate (PMMA)/Palm oil/ZnO nanocomposite films of concentrations 0, 0.5, 1, 2, 5, 10, and 15 wt% were prepared by solution casting technique. Tween 80 was used as a surfactant. The prepared films were characterised by different techniques in addition to antimicrobial and cytotoxicity tests. The scanning electron microscope (SEM) micrographs of fractured surfaces of the films showed that palm oil (PO) and Tween 80 enhanced ZnO NPs dispersion. An excess ZnO loading led to polymer saturation with ZnO NPs which accumulate on PMMA surface. X-ray diffraction (XRD) measurements confirmed SEM results as the crystallinity increased by ZnO NPs loading and decreased by excess loading. In addition, the presence of PO and Tween 80 enhanced thermal stability of pure PMMA and the optimum concentration is 0.5 wt% ZnO NPs. Further, the permittivity (ε′), dielectric loss (ε′′), and electrical conductivity (σ) were investigated. It was found that PO addition increased the values of ε′, ε′′, and σ of PMMA. Upon ZnO loading, these values increased up to 10 wt% ZnO NPs then decreased upon reaching 15 wt% ZnO NPs. The conductivity values revealed that the prepared nanocomposites can perform as antistatic materials for lower ZnO content and electrostatic dissipation application at 10 wt% ZnO. The antimicrobial and cytotoxicity studies revealed that the prepared films are nontoxic and the antimicrobial properties of the films against Staphylococcus aureus, Enterococcus faecalis and Candida albicans were enhanced by PO and ZnO NPs addition.
Regulation of the programmed cell death protein 1/programmed cell death ligand 1 axis in relapsing–remitting multiple sclerosis
Authors: Tsaktanis Thanos , Linnerbauer Mathias , Lößlein Lena , Farrenkopf Daniel , Vandrey Oliver , Peter Anne , Cirac Ana , Beyer Tobias , Nirschl Lucy , Grummel Verena , Mühlau Mark , Bussas Matthias , Hemmer Bernhard , Quintana Francisco J , Rothhammer Veit 
Published: July 2023

Abstract
The programmed cell death protein 1/programmed cell death ligand 1 axis plays an important role in the adaptive immune system and has influence on neoplastic and inflammatory diseases, while its role in multiple sclerosis is unclear. Here, we aimed to analyse expression patterns of programmed cell death protein 1 and programmed cell death ligand 1 on peripheral blood mononuclear cells and their soluble variants in multiple sclerosis patients and controls, to determine their correlation with clinical disability and disease activity. In a cross-sectional study, we performed in-depth flow cytometric immunophenotyping of peripheral blood mononuclear cells and analysed soluble programmed cell death protein 1 and programmed cell death ligand 1 serum levels in patients with relapsing–remitting multiple sclerosis and controls. In comparison to control subjects, relapsing–remitting multiple sclerosis patients displayed distinct cellular programmed cell death protein 1/programmed cell death ligand 1 expression patterns in immune cell subsets and increased soluble programmed cell death ligand 1 levels, which correlated with clinical measures of disability and MRI activity over time. This study extends our knowledge of how programmed cell death protein 1 and programmed cell death ligand 1 are expressed in the membranes of patients with relapsing–remitting multiple sclerosis and describes for the first time the elevation of soluble programmed cell death ligand 1 in the blood of multiple sclerosis patients. The distinct expression pattern of membrane-bound programmed cell death protein 1 and programmed cell death ligand 1 and the correlation between soluble programmed cell death ligand 1, membrane-bound programmed cell death ligand 1, disease and clinical factors may offer therapeutic potential in the setting of multiple sclerosis and might improve future diagnosis and clinical decision-making.
Efficacy on resynchronization and longitudinal contractile function comparing His-bundle pacing with conventional biventricular pacing: a substudy to the His-alternative study
Authors: Højgaard E V , Philbert B T , Linde J J , Winsløw U C , Svendsen J H , Vinther M , Risum N 
Published: July 2023

Abstract

Aims
His-bundle pacing has emerged as a novel method to deliver cardiac resynchronization therapy (CRT). However, there are no data comparing conventional biventricular (BiV)-CRT with His-CRT with regard to effects on mechanical dyssynchrony and longitudinal contractile function.

Methods and results
Patients with symptomatic heart failure, left ventricular ejection fraction ≤ 35%, and left bundle branch block (LBBB) by strict ECG criteria were randomized 1:1 to His-CRT or BiV-CRT. Two-dimensional strain echocardiography was performed prior to CRT implantation and at 6 months after implantation. Differences in changes in mechanical dyssynchrony (standard deviation of time-to-peak in 12 midventricular and basal segments) and regional longitudinal strain in the six left ventricular walls were compared between the BiV-CRT and His-CRT groups.
In the on-treatment analysis, 31 received BiV-CRT and 19 His-CRT. In both groups, mechanical dyssynchrony was significantly reduced after 6 months [BiV group from 120 ms (±45) to 63 ms (±22), P &lt; 0.001, and His group from 116 ms (±54) to 49 ms (±11), P &lt; 0.001] but no significant differences in changes could be demonstrated between groups [−9.0 ms (−36; 18), P = 0.50]. Global longitudinal strain (GLS) improved in both groups [BiV group from −9.1% (±2.7) to −10.7% (±2.6), P = 0.02, and His group from −8.6% (±2.1) to −11.1% (±2.0), P &lt; 0.001], but no significant differences in changes could be demonstrated from baseline to follow-up [−0.9% (−2.4; −0.6), P = 0.25] between groups. There were no regional differences between groups.

Conclusion
In heart failure, patients with LBBB, BiV-CRT, and His-CRT have comparable effects with regard to improvements in mechanical dyssynchrony and longitudinal contractile function.
Long-term dietary iron intake and risk of non-fatal cardiovascular diseases in the China Health and Nutrition Survey
Authors: Chen Peiyan , Wu Shangling , He Jingjing , Sui Yi , Li Keji , Fang Aiping 
Published: July 2023

Abstract

Aims
We aimed to investigate the association of long-term dietary iron intake with the risk of non-fatal cardiovascular diseases (CVDs), myocardial infarction (MI), and stroke in Chinese populations with predominantly plant-based diets by sex.

Methods and results
A total of 17 107 participants (8569 men and 8538 women) aged 18–80 years in the China Health and Nutrition Survey (CHNS) 1989–2015 were included. Dietary intake was assessed repeatedly by three consecutive 24-h dietary recalls. Cox proportional hazard models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). During a median follow-up of 11.1 years, the adjusted HRs (95% CIs) for non-fatal CVDs risk across quintiles of total iron intake in men were 1.00, 0.65 (0.46–0.93), 0.54 (0.37–0.78), 0.66 (0.46–0.94), 0.69 (0.47–1.03), but no significant association in women. Similar associations were found for stroke risk, but not for MI risk. The dose-response curves for the association of total iron and non-heme iron intake with the risk of non-fatal CVDs and stroke followed a reverse J-shape only in men and similar reverse J-shaped association of heme iron intake with non-fatal CVDs and stroke risk in both men and women (P-non-linearity &lt;0.05).

Conclusion
Moderate dietary iron intake may protect against non-fatal CVDs and stroke, especially in Chinese men consuming plant-based diets. Both quantity and quality of dietary iron intake should be considered in the prevention of non-fatal CVDs due to differences in dietary patterns among diverse populations.
The Impact of Caregiving History on Later-Life Self-Perceptions of Aging
Authors: Hu Rita Xiaochen , Larkina Marina , Smith Jacqui 
Published: July 2023

Abstract

Objectives
Theories suggest that self-perceptions of aging (SPA) reflect structural and cultural ageism together with an individual’s personal life experiences. We examine the impact of an individual’s history of informal caregiving on their SPA.

Methods
Using data from the Health and Retirement Study (HRS, N = 8,372, age range 50–102 years), we investigated caregiving history as a determinant of later-life SPA. HRS participants provided reports of up to 5 episodes of caregiving, the life-course timing of each episode (start/end year), and their relationship with the care recipients. SPA was measured by the HRS Attitudes Toward Own Aging Scale. We conducted linear regressions to examine associations between specific caregiving histories and later-life SPA. Models included controls for current sociodemographic and health status.

Results
Individuals who were ever a caregiver reported more negative SPA than noncaregivers. Variations in the impact of histories of caregiving were also revealed. Specifically, compared to people who had cared for adult(s) only, HRS participants who cared for both a child with special needs and an adult reported more negative SPA later in life.

Discussion
The study provides insight into potential life-course precursors of SPA and highlights the importance of conceptualizing caregiving history as a complex life experience that might affect an individual’s SPA later in life.
Overview and understanding of mental health and psychosocial support in Afghanistan
Authors: Schwartz Lyla , Lane Hannah , Hassanpoor Zainab 
Published: July 2023

Abstract
More than four decades of war in Afghanistan has been both a main driver for poor mental health, and a barrier to the development of crucial mental health services. A study conducted by BMC Psychiatry in 2021, across eight regions in Afghanistan, found staggering levels of depressive and anxiety disorders among the general population. Almost one-half of those interviewed (47.12%) reported having high levels of distress in the last month, and almost 40% (39.44%) reported experiencing impairment to their lives due to poor mental health. Yet, despite the common experiences of much of the population, mental health is a hugely stigmatized topic of discussion in Afghanistan, due to a myriad of cultural, religious, socioeconomic and environmental factors. And now, under the de-facto Taliban government, mental health has been deprioritized in the face of a crumbling economy and acute levels of poverty, all but forgotten. This paper sought to review the impact and change to mental health services under the de-facto government, and to provide the reader with greater awareness into the current situation in Afghanistan and equip them with insight into how to respond to the mental health needs of Afghans.
The genomic characterization of carbapenem-resistant Serratia marcescens at a tertiary hospital in South Africa
Authors: Overmeyer Amanda Julia , Prentice Elizabeth , Brink Adrian , Lennard Katie , Moodley Clinton 
Published: July 2023

Abstract

Background
Serratia marcescens is an opportunistic nosocomial pathogen, and recent reports have highlighted the rapid increase in multidrug resistance in this organism. There is a paucity in genomic data for carbapenem-resistant S. marcescens (CRSM).

Methods
A retrospective cohort study describing laboratory-confirmed CRSM from a tertiary academic hospital in Cape Town, South Africa, for the period 2015–20, was performed. Stored CRSM and contemporary isolates were submitted for WGS using Illumina MiSeq, with the Nextera DNA Flex Library Preparation Kit. Sequence data were analysed in-house using srst2 and Tychus, and CRSM and contemporary isolates were compared.

Results
Twenty-one CRSM and four contemporary isolates were sequenced and analysed. Twenty-four different resistance genes were identified, with all isolates having at least two resistance genes, and seventeen isolates harbouring three or more genes. This correlated well with phenotypic results. The blaOXA-48-like carbapenemase was the most common carbapenemase identified, in 86% (18/21) of CRSM. A core SNP difference tree indicated that the CRSM could be grouped into three clusters. Eleven isolates had shared plasmids. Several genes and SNPs were identified in the CRSM, which may putatively augment virulence, but this requires further functional characterization.

Conclusions
A diverse resistome was observed in CRSM, which was also reflected phenotypically, with blaOXA-48-like the most commonly carbapenemase. Though distinct clusters were observed, no clonality was noted, and a limited number of isolates shared plasmids. This study provides genomic data for emerging CRSM and highlights the importance of ongoing genomic surveillance to inform infection prevention control and antimicrobial stewardship initiatives.
Molecular species delimitation reveals hidden endemism in Faxonius placidus (Hagen 1870) (Decapoda: Astacidea: Cambaridae) in southeastern USA
Authors: Hildreth Parker L , Hurt Carla R , Simmons Jeffrey W , Williams Carl E , Leckie Brian 
Published: July 2023

Abstract
Molecular surveys are critical for understanding species boundaries and evolutionary relationships of North American crayfishes, as traditional morphological characters used for taxonomy frequently misrepresent crayfish diversity. The bigclaw crayfish, Faxonius placidus (Hagen, 1870), is currently described as a widely distributed crayfish that is common throughout the Cumberland, Tennessee, and Lower Ohio river drainages. The geographic distribution of F. placidus is based on identifications using traditional morphological characters including the first-form male gonopod, chelae, and rostrum. Within F. placidus, color pattern variation is specific to populations separated by hydrogeographic barriers. We used DNA barcoding data (mtDNA-COI) and genome-wide molecular markers (nuclear SNPs) to examine geographic patterns of genetic variation in F. placidus within the Cumberland and Tennessee river drainages. The federally endangered Nashville crayfish, F. shoupi (Hobbs, 1948), was included in our analyses, as previous phylogenetic reconstructions suggest F. placidus is paraphyletic with respect to F. shoupi. Phylogenetic reconstructions and molecular species delimitation identified four genetically distinct lineages within F. placidus that are paraphyletic with respect to F. shoupi. Our results add to numerous studies demonstrating the utility of robust molecular analyses for understanding the biodiversity of North American crayfishes.
Estimating the information content of genetic sequence data
Authors: Thorvaldsen Steinar , Hössjer Ola 
Published: July 2023

Abstract
A prominent problem in analysing genetic information has been a lack of mathematical frameworks for doing so. This article offers some new statistical methods to model and analyse information content in proteins, protein families, and their sequences. We discuss how to understand the qualitative aspects of genetic information, how to estimate the quantitative aspects of it, and implement a statistical model where the qualitative genetic function is represented jointly with its probabilistic metric of self-information. The functional information of protein families in the Cath and Pfam databases are estimated using a method inspired by rejection sampling. Scientific work may place these components of information as one of the fundamental aspects of molecular biology.
Physical Health and Well-being: Updates and the Way Ahead
Authors: Phillips Angela K , Keller Margaux F , McClung James P , Steele Nancy , Witkop Catherine T , Wu T John 
Published: July 2023

ABSTRACT

Introduction
The Women in Combat Summit 2021 “Forging the Future: How Women Enhance the Fighting Force” took place during February 9-11, 2021, via a virtual conference platform. The third and final day of the Summit regarded the physical health and well-being of military women and included the topics of urogenital health, nutrition and iron-deficiency anemia, unintended pregnancy and contraception, and traumatic brain injury.

Materials and methods
After presentations on the topics earlier, interested conference attendees were invited to participate in focus groups to discuss and review policy recommendations for physical health and well-being in military women. Discussions centered around the topics discussed during the presentations, and suggestions for future Women in Combat Summits were noted. Specifics of the methods of the Summit are presented elsewhere in this supplement.

Results
We formulated research and policy recommendations for urogenital health, nutrition and iron-deficiency anemia, contraception and unintended pregnancy, and traumatic brain injury.

Conclusions
In order to continue to develop the future health of military women, health care providers, researchers, and policymakers should consider the recommendations made in this supplement as they continue to build on the state of the science and forge the future.