bluuebunny/crossref_metadata_2025_split huggingface dataset:
(094) Sexual Emergencies in Women
Authors: Dominguez-Bali A , Rey C , Dominguez-bali C , Baqer A , Sharma R , Hassan Z , Marquez L 
Published: May 2023

Abstract

Introduction
Sexual emergencies in female patients are more common than people think. They represent medical curiosities more than pathologies for which we should be prepared to treat. This review and the presentation of our cases shows how extensive and important is this area in the medical practice and why every single physician should be prepared to confront them. Gynecologist, surgeons, sexologists, and ER physicians are familiarized with some of the sexual emergencies in women that called the attention of the medical community. However, the broad spectrum of those disorders is not well-known.

Objective
1. Show the magnitude of sexual emergencies in women nationally and internationally. 2. Describe how they can vary according with the place, culture, and societies. 3. To learn the methods of diagnosis and treatment of these ample variety of conditions.

Methods
Based on the multiple cases seen in the ER of our facility, an extensive review of the literature was done, and the cases are presented to show the magnitude, variety, and diversity of cases in the different areas of the medical field.

Results
The review includes: I. The common coital emergencies in neurology (benign coital headache, subarachnoid hemorrhage, intracerebral bleeding, subdural hemorrhage, cerebral vascular accidents), urology (ureterovesical foreign bodies, obstructive uropathies), cardiology (sudden cardiac death, myocardial infarction), gynecology (vaginal lacerations and/or evisceration and death with/without previous gynecological surgeries), obstetrical (postpartum dyspareunia secondary or not to episiotomy or vaginal lacerations; postcoital preterm labor), immunological (local or systemic, anaphylactic allergic reactions). II. Common autoerotic emergencies in gastroenterology (foreign objects in rectum, vagina, oropharyngeal/mandibular lesions), as well as “body packers” cases (swallowed latex balloons for smuggling in the GI tract, rectum, or vagina). III. Sexual assault IV. Sexual dysfunction: Hyperactive arousal disorders (compulsive hunt for orgasms with/without attempt or real suicide, hypersexuality related to SSRI use). V. Sociosexual issues: Killings for jealousy during sex, infidelity, castration like Lorena Bobbitt case.

Conclusions
The epidemiology of these pathologies varies from country to country, and state to state, and includes women of any age, race, religion, and culture. Finally, a review of these diagnostic methods and treatment are presented.

Disclosure
No
(096) #SexMed: The Sexual Medicine Tag Ontology Project
Authors: Patel N , Davenport A , Iglesia C , Kingsberg S 
Published: May 2023

Abstract

Introduction
Female sexual dysfunction includes many different conditions that involve desire, arousal, orgasm, and pain. More than 40% of American women report sexual problems and nearly 12% meet the criteria for a diagnosed sexual dysfunction. Given the sensitivity of the topic, many women turn to the Internet to find information. In specific, social media allows users to interact with others by creating, viewing and commenting on content. “Hashtags” are a type of metadata tag that are preceded by the symbol “#”. By adding this symbol, social media platforms are able to compile relevant information in a single place, streamlining pertinent information and allowing for users to find others with similar interests and create new communities based on a common interest.

Objective
The aim of this study is to develop a tag ontology and to identify the top social media influencers for female sexual medicine.

Methods
Symplur is a Twitter analytic tool that identifies tweets and hashtags related to a specific topic. This software was used to create a “tag ontology”, a standardized list of hashtags, using the search terms “sexual medicine”, “women’s sexual health” and “female sexual dysfunction” between November 1, 2020 and November 1, 2022. The hashtag ontology list created by Symplur was then reviewed by social media influencers for inclusivity and external validation. A proprietary Symplur algorithm was used to identify Top Influencers.

Results
We identified 3800 tweets during the study time period. In total, the ontology included 22 terms (Table 1). Medical and vernacular terms were included in the “tag ontology” so the list included terms accessible to both women and healthcare providers. Of the top 20 influencers, 10 were physicians, 7 were major medical societies, 2 were academic journals and 1 was industry related. A visual of the top 15 influencers appears in Figure 1.

Conclusions
Creation of a standardized hashtag ontology consolidates communication between healthcare providers and patients about specific health information. Our study has created a “tag ontology” for female sexual medicine that can be utilized to streamline pertinent information between providers and women.

Disclosure
No
Effects of the Noise Reduction and Communication Management Headset System SLOS on Noise and Stress of Medical Laboratory Workers
Authors: Lehrke Jan , Lauff Sören , Mücher Jan , Friedrich Martin G , Boos Margarete 
Published: May 2023

Abstract

Objective
To investigate the effects of the Silent Laboratory Optimization System (SLOS), a technical-noise reduction and communication-management system, on noise load and stress among medical-laboratory workers.

Methods
We conducted a quasiexperimental field study (20 days with SLOS as the experimental condition, and 20 days without SLOS as the control condition) in a within-subjects design. Survey data from 13 workers were collected before and after the shift. Also, a survey was conducted after the control and experimental conditions, respectively. Noise was measured in dBA and as a subjective assessment. Stress was operationalized via a stress composite score (STAI and Perkhofer Stress Scale), the Perceived Stress Scale (PSS), an exhaustion score (Leipziger StimmungsBogen in German [LSB]), and salivary cortisol values in µg/L.

Results
SLOS users perceived significantly less noise (V = 76.5; P =.003). Multilevel models revealed a stress reduction with the SLOS on the composite score, compared with a stress increase in the control condition (F[1, 506.99] = 6.00; P = .01). A lower PSS score (F[1,13] = 4.67; P = .05) and a lower exhaustion level (F[1, 508.72] = 9.057; P = .003) in the experimental condition were found, whereas no differences in cortisol (F[1,812.58.6] = 0.093; P = .76) were revealed.

Conclusion
The workers showed reduced noise perception and stress across all criteria except cortisol when using SLOS.
Influence of Gaunt factors on the calculation of the Stark broadening parameters for 56 spectral lines of V ii with high industrial and astrophysical interest
Authors: de Andrés-García I , Isidoro-García L , Fernández F , Porro J , Colón C 
Published: May 2023

ABSTRACT
Recently, in 2020, Stark broadening parameters have been measured for spectral lines belonging to 75 vanadium ii (V ii) multiplets. For some of them, there are published calculations in the literature. However, these lines are not sufficient for the analysis of the lines present in the metal-poor star HD 8493. When new calculations by the Griem approximation are performed and compared with the experimental results, in some cases there is a difference of a factor of 7. It is clear that the problem lies, as already suggested some years ago in a theoretical paper by Douglas H. Sampson, in the poor approximation proposed by van Regemorter for the Gaunt factors used in the Griem approximation. In this work, we have performed broadening measurements of 3276.12 and 3715.46 Å V ii lines that confirmed the previous measurements of 2020. Subsequently, we performed a more accurate calculation using the procedure to calculate the Gaunt factors suggested by Sampson, obtaining results very close to the experimental values. These allowed us to assume that the calculations performed for 56 lines ranging between 3700 and 4600 Å (present in the photospheres of the Sun and the metal-poor star HD 8493), and without experimental information, are more accurate using the Gaunt factors proposed by Sampson.
A generalizable framework to comprehensively predict epigenome, chromatin organization, and transcriptome
Authors: Zhang Zhenhao , Feng Fan , Qiu Yiyang , Liu Jie 
Published: May 2023

Abstract
Many deep learning approaches have been proposed to predict epigenetic profiles, chromatin organization, and transcription activity. While these approaches achieve satisfactory performance in predicting one modality from another, the learned representations are not generalizable across predictive tasks or across cell types. In this paper, we propose a deep learning approach named EPCOT which employs a pre-training and fine-tuning framework, and is able to accurately and comprehensively predict multiple modalities including epigenome, chromatin organization, transcriptome, and enhancer activity for new cell types, by only requiring cell-type specific chromatin accessibility profiles. Many of these predicted modalities, such as Micro-C and ChIA-PET, are quite expensive to get in practice, and the in silico prediction from EPCOT should be quite helpful. Furthermore, this pre-training and fine-tuning framework allows EPCOT to identify generic representations generalizable across different predictive tasks. Interpreting EPCOT models also provides biological insights including mapping between different genomic modalities, identifying TF sequence binding patterns, and analyzing cell-type specific TF impacts on enhancer activity.
Sequential disruption of SPLASH-identified vRNA–vRNA interactions challenges their role in influenza A virus genome packaging
Authors: Jakob Celia , Lovate Gabriel L , Desirò Daniel , Gießler Lara , Smyth Redmond P , Marquet Roland , Lamkiewicz Kevin , Marz Manja , Schwemmle Martin , Bolte Hardin 
Published: May 2023

Abstract
A fundamental step in the influenza A virus (IAV) replication cycle is the coordinated packaging of eight distinct genomic RNA segments (i.e. vRNAs) into a viral particle. Although this process is thought to be controlled by specific vRNA–vRNA interactions between the genome segments, few functional interactions have been validated. Recently, a large number of potentially functional vRNA–vRNA interactions have been detected in purified virions using the RNA interactome capture method SPLASH. However, their functional significance in coordinated genome packaging remains largely unclear. Here, we show by systematic mutational analysis that mutant A/SC35M (H7N7) viruses lacking several prominent SPLASH-identified vRNA–vRNA interactions involving the HA segment package the eight genome segments as efficiently as the wild-type virus. We therefore propose that the vRNA–vRNA interactions identified by SPLASH in IAV particles are not necessarily critical for the genome packaging process, leaving the underlying molecular mechanism elusive.
GePI: large-scale text mining, customized retrieval and flexible filtering of gene/protein interactions
Authors: Faessler Erik , Hahn Udo , Schäuble Sascha 
Published: May 2023

Abstract
We present GePI, a novel Web server for large-scale text mining of molecular interactions from the scientific biomedical literature. GePI leverages natural language processing techniques to identify genes and related entities, interactions between those entities and biomolecular events involving them. GePI supports rapid retrieval of interactions based on powerful search options to contextualize queries targeting (lists of) genes of interest. Contextualization is enabled by full-text filters constraining the search for interactions to either sentences or paragraphs, with or without pre-defined gene lists. Our knowledge graph is updated several times a week ensuring the most recent information to be available at all times. The result page provides an overview of the outcome of a search, with accompanying interaction statistics and visualizations. A table (downloadable in Excel format) gives direct access to the retrieved interaction pairs, together with information about the molecular entities, the factual certainty of the interactions (as verbatim expressed by the authors), and a text snippet from the original document that verbalizes each interaction. In summary, our Web application offers free, easy-to-use, and up-to-date monitoring of gene and protein interaction information, in company with flexible query formulation and filtering options. GePI is available at https://gepi.coling.uni-jena.de/.
Can Banks Save Mountains?
Authors: Haushalter David , Henry Joseph J , Iliev Peter 
Published: May 2023

Abstract
We study bank policies to limit lending to companies engaged in mountaintop removal (MTR) coal mining, a form of coal extraction that has raised many environmental concerns. Using the staggered introduction of these policies, we document that these policies did not lead to meaningful changes in average bank lending or MTR mining. However, larger banks, banks that are under media pressure, and banks operating in the affected states are more likely to reduce MTR loans. Our results are consistent with the hypothesis that banks announced these policies under pressure and to improve their green credentials. (JEL G21, G28, G32)
Authors have furnished an Internet Appendix, which is available on the Oxford University Press Web site next to the link to the final published paper online.
Taxation of the Hungarian asset management foundation, trust and hybrid trust
Authors: Menyhei Ákos 
Published: May 2023

Abstract
How should new legal forms—trusts, asset management foundations and hybrid trusts—be treated and their taxation implemented into an existing tax regime? Is tax exemption the best way forward or should the new legal forms be included in the tax regime that applies to taxable entities? Who should be taxed and when? The legal instrument itself, the trustee or the beneficiary? Should a look-through approach be applied to provide for tax-neutral treatment of the new vehicles? In this article, the author explains the key issues and significant benefits of the taxation of trusts, AMFs and hybrid trusts, providing answers to these questions.
Taming the Italian ‘Trojan horse’: the a non domino sales of cultural objects
Authors: Giardini Giuditta 
Published: May 2023

Abstract
For a long time, scholars have argued that Article 1153 of the Italian Civil Code, regulating the good faith purchase of goods, creates a ‘congenial place’ for buying stolen cultural objects. What is an Italian domestic concern becomes international in international cases where Italian law is found to be applicable. Consequently, both scholarship and case law have looked into the problem and questioned the applicability of the article to cultural objects. This Contribution explores the contours of the norm, explains how it risks playing the role of the ‘Trojan horse’, and then shows why it was essential for the Italian Supreme Court to intervene. In deciding on a case concerning the ownership rights of Peruvian and Chilean cultural property sold a non domino and located in Italy, the Italian Supreme Court upheld the ruling of the lower Court and applied the principles of international public order derived from cultural conventions. Where the application of Italian law, specifically of Article 1153 of the Italian Civil Code was necessary, the Supreme Court strengthened the article's constitutive element of good faith by making hermeneutical use of Article 4 of the 1995 Unidroit Convention on Stolen or Illegally Exported Cultural Objects. The resulting good faith requires a higher level of care on the art-buyer side, a standard that changes depending on the character of the party concerned. Ultimately the Contribution points to the importance of the choice that the Supreme Court made to identify a dynamic bonam fidem to cope with the problems posed by Article 1153 of the Italian Civil Code.
Improved Maximal Workload and Systolic Blood Pressure After Cardiac Rehabilitation Following Thoracic Aortic Repair
Authors: Koenders Niek , van Zetten Henrita , Smulders Michelle , Verra Martin L. , van Kimmenade Roland R. J. , van Brakel Thomas , Eijsvogels Thijs M. H. , Smith Tim 
Published: May 2023

Purpose:
It is of clinical importance to gain more knowledge about the risks and benefits of exercise in patients recovering from thoracic aortic repair. Therefore, the aim of this review was to perform a meta-analysis on changes in cardiorespiratory fitness, blood pressure, and the incidence of adverse events during cardiac rehabilitation (CR) in patients recovering from thoracic aortic repair.

Review Methods:
We performed a systematic review and random-effects meta-analysis of outcomes before versus after outpatient CR in patients recovering from thoracic aortic repair. The study protocol was registered (PROSPERO CRD42022301204) and published. MEDLINE, EMBASE, and CINAHL were systematically searched for eligible studies. Overall certainty of evidence was scored with Grading of Recommendations Assessment, Development, and Evaluation (GRADE).

Summary:
We included five studies with data from in total 241 patients. Data from one study could not be used in our meta-analysis because they were provided in a different unit of measure. Four studies with data of 146 patients were included in the meta-analysis. The mean maximal workload increased with 28.7 W (95% CI: 21.8-35.6 W, n = 146, low certainty of evidence). The mean systolic blood pressure during exercise testing increased with 25.4 mm Hg (95% CI: 16.6-34.3, n = 133, low certainty of evidence). No exercise-induced adverse events were reported. These outcomes indicate that CR seems beneficial and safe to improve exercise tolerance in patients recovering from thoracic aortic repair, although outcomes were based on data from a small, heterogeneous group of patients.
ENLARGEMENT OF CHOROIDAL NEOVASCULARIZATION BEFORE RECURRENCE AFTER PHOTODYNAMIC THERAPY FOR PACHYCHOROID NEOVASCULOPATHY
Authors: Hikichi Taiichi , Kubo Natsuki , Tabata Moe , Kurabe Haruka 
Published: May 2023

Purpose:
To investigate predictors of recurrent exudation in choroidal neovascularization (CNV) of pachychoroid neovasculopathy after photodynamic therapy (PDT).

Methods:
Consecutive, treatment-naïve, symptomatic patients with pachychoroid neovasculopathy with subfoveal retinal fluid treated with PDT and followed for 18 months were studied retrospectively. Choroidal neovascularization areas were calculated from optical coherence tomography angiography images obtained at various time points after the initial PDT.

Results:
In 52 eyes, the subfoveal retinal fluid resolved completely three months after PDT; in 23 (44%) eyes, exudation recurred during the 18-month follow-up period. In 29 eyes with no recurrence, the mean baseline square root of the CNV area of 1.91 mm (95% CI, 0.27) decreased significantly (P = 0.006) to 1.47 mm (95% CI, 0.16) at three months after PDT and decreased further until 12 months after PDT (mean, 1.26 mm; 95% CI, P < 0.001) and was maintained thereafter. In 23 eyes with a recurrence, the square root of the CNV area enlarged significantly (P = 0.028) from 1.43 mm (95% CI, 0.21) at examination three months before the recurrence to 1.73 mm (95% CI, 0.18) at recurrence.

Conclusion:
Choroidal neovascularization enlargement during the follow-up period after PDT for pachychoroid neovasculopathy may predict recurrence.
Long-term outcomes of liver transplantation for alcohol-related liver disease
Authors: Lin Niang-Cheng , Liu Chinsu , Chen Cheng-Yen , Lei Hao-Jan , Tsou Yi-Fan , Kuo Fang-Cheng , Chou Shu-Cheng , Chung Meng-Hsuan , Hsia Cheng-Yuan , Loong Che-Chuan , Wang Shen-Chih , Lee Oscar K. , Tsai Hsin-Lin 
Published: May 2023

Background:
Liver transplantation (LT) is being increasingly performed for alcohol-related liver disease (ALD). It is unclear whether the increasing frequency of LTs in ALD patients has a negative impact on deceased-donor (DDLT) allocation and whether the current policy of 6 months of abstinence before transplantation effectively prevents recidivism after transplantation or improves long-term outcomes.

Methods:
A total of 506 adult LT recipients, including 97 ALD patients, were enrolled. The outcomes of ALD patients were compared with those of non-ALD patients. The 97 ALD patients were further divided into group A (6-month abstinence) and group N (nonabstinence) based on the pretransplant alcohol withdrawal period. The incidence of relapsed drinking and the long-term outcomes were compared between the two groups.

Results:
The prevalence of LT for ALD significantly increased after 2016 (27.0% vs 14.0%; p < 0.01), but the frequency of DDLT for ALD remained unchanged (22.6% vs 34.1%, p = 0.210). After a median follow-up of 56.9 months, patient survival was comparable between the ALD and non-ALD patients (1, 3, and 5 years posttransplant: 87.6%, 84.3%, and 79.5% vs 82.8%, 76.6%, and 72.2%, respectively; p = 0.396). The results were consistent irrespective of the transplant type and disease severity. In ALD patients, 22 of the 70 (31.4%) patients reported relapsed drinking after transplantation, and the prevalence in group A had a higher tendency than that in group N (38.3% vs 17.4%, p = 0.077). Six months of abstinence or nonabstinence did not result in a survival difference, and de novo malignancies were the leading cause of late patient death in ALD patients.

Conclusion:
LT achieves favorable outcomes for ALD patients. Six months of abstinence pretransplant did not predict the risk of recidivism after transplantation. The high incidence of de novo malignancies in these patients warrants a more comprehensive physical evaluation and better lifestyle modifications to improve long-term outcomes.
The impact of cancer-related lower extremity lymphedema on patient quality of life: a qualitative meta-synthesis
Authors: Bowman Catharine , Baydoun Mohamad , Carlson Linda E. 
Published: May 2023

Abstract
Lower extremity lymphedema (LEL) is a common and potentially debilitating chronic condition associated with cancer treatment. Research has outlined the substantial psychosocial and quality-of-life (QOL) sequelae associated with lymphedema, primarily of the upper extremities and through the use of quantitative methods. The purpose of this systematic review was to summarize, synthesize, and appraise qualitative literature exploring the impact of LEL on patients' QOL and psychosocial well-being after cancer treatment. Nine databases were searched for qualitative research articles published before May 1, 2022. Six eligible articles were included. Four studies used individual semistructured interviews, one used open-ended survey questions, and one used structured interviews. There was a total of 248 participants (average age: 59.8 years) included in the reviewed articles, ranging from 13 to 178 participants. Most participants were women and had a history of gynecologic cancer. All studies described psychosocial challenges experienced by individuals with cancer-related LEL. Four key themes were identified: (1) physical burden and functional limitations, (2) psychologic and emotional impacts, (3) financial implications, and (4) relational and social sequelae. Despite available qualitative data suggesting that cancer-related LEL has negative consequences on patients' QOL, there is still a significant need for increased research to broaden our understanding of the cancer-related LEL experience to better inform policy and practical guideline development.