bluuebunny/crossref_metadata_2025_split huggingface dataset:
The association between the problem list and chronic pain management
Authors: Rylee Tina L. , Copenhaver David , Drake Christiana , Joseph Jill 
Published: January 2023

Abstract
Background
Roughly a quarter of the US population suffers from moderate to severe chronic pain for at least six months in any given year. The complexity of managing chronic pain has encouraged providers to use innovative methods to address it. Research has shown that problem lists are potential tools that support the care of patients with diabetes and chronic kidney disease.

Objectives
To examine the extent to which the inclusion of chronic pain in a problem list is associated with follow-up specialty pain care.

Methods
The association between chronic pain documentation on the problem list and specialty pain care was investigated in this retrospective cohort study using 4531 patient records.

Results
Chronic pain documentation in the problem list was associated with higher odds of receiving specialty pain care. The most common diagnosis was chronic pain (69.7%). A migraine diagnosis was associated with decreased odds of receiving specialty care, and chronic pain syndrome was associated with increased odds of receiving specialty care compared with the other chronic pain groups.

Conclusion
Documenting chronic pain on the problem list was associated with a higher likelihood of patients receiving specialty pain care.
Target benefit pension plan with longevity risk and intergenerational equity
Authors: Rong Ximin , Tao Cheng , Zhao Hui 
Published: January 2023

AbstractWe study a stochastic model for a target benefit pension plan suffering from rising longevity and falling fertility. Policies for postponing retirement are carried out to hedge the payment difficulties caused by the aging population. The plan members’ contributions are set in advance while the pension payments reflect intergenerational equity by a target payment level and intergenerational risk sharing by an adjustment. The pension fund is invested in both a risk-free asset and a risky asset. Applying the stochastic optimal control methods, we derive analytic solutions for optimal investment and benefit payment strategies which minimize the benefit risk. Besides, an optimal delayed retirement age which can hedge against the aging phenomenon under certain parameters is given. Therefore, it can provide a basis for quantifying the delay of retirement time.
Transnational Strategies of Legitimation in the 1990s: The Togolese Regime and its Exiled Opposition in Ghana
Authors: Raunet Nathalie 
Published: January 2023

AbstractAfter a failed transition to democracy in the 1990s in Togo, the opposition took refuge in Ghana, outside of the regime’s reach. Why and how did the regime react to transnational dissent? Analyzing an unpublished RPT-produced press review and the opposition press in Ghana and Togo, Raunet argues that the Togolese regime used the foreign press, the language of legality, and the politics of belonging to consolidate itself and shape a public image of apparent legitimacy. She suggests that the skillful adaptation of legitimation narratives is key in understanding the “internal logic” of authoritarian regimes and their prospects of survival.
Extinction: A synthesis of disciplines for theoretical and practical advances
Authors: Brook Barry W. , Alroy John 
Published: January 2023

Abstract
Extinction is a new open-access journal focused on the patterns and processes underlying the loss of biodiversity. It aims to inform conservation efforts, with a broad spatial and temporal scope. Extinction biology – the scientific study of species loss – has a long history and has recently become a more interdisciplinary and integrated field. This journal offers a unique, synthetic forum in which to present cutting-edge research and discuss its implications. This includes ecological, molecular, paleontological, and social perspectives, based on empirical data, theory, and modelling, to understand extinction processes. By tackling the big challenges, the research published in Extinction will be valuable for researchers and practitioners concerned with extinction and its role in shaping the history and future of life on Earth.
MetaFunc: taxonomic and functional analyses of high throughput sequencing for microbiomes
Authors: Sulit Arielle Kae , Kolisnik Tyler , Frizelle Frank Antony , Purcell Rachel , Schmeier Sebastian 
Published: January 2023

AbstractThe identification of functional processes taking place in microbiome communities augment traditional microbiome taxonomic studies, giving a more complete picture of interactions taking place within the community. While there are applications that perform functional annotation on metagenomes or metatranscriptomes, very few of these are able to link taxonomic identity to function or are limited by their input types or databases used. Here we present MetaFunc, a workflow which takes RNA sequences as input reads, and from these (1) identifies species present in the microbiome sample and (2) provides gene ontology annotations associated with the species identified. In addition, MetaFunc allows for host gene analysis, mapping the reads to a host genome, and separating these reads, prior to microbiome analyses. Differential abundance analysis for microbe taxonomies, and differential gene expression analysis and gene set enrichment analysis may then be carried out through the pipeline. A final correlation analysis between microbial species and host genes can also be performed. Finally, MetaFunc builds an R shiny application that allows users to view and interact with the microbiome results. In this paper, we showed how MetaFunc can be applied to metatranscriptomic datasets of colorectal cancer.
Religion and the Justification of Rights - Discussed: Faith, Freedom, and Family: New Studies in Law and Religion. By John Witte, Jr. Edited by Norman Doe and Gary S. Hauk. Tübingen: Mohr Siebeck, 2021. €99.00 (paper); €99.00 (digital). ISBN: 9783161608773. -
The Blessings of Liberty: Human Rights and Religious Freedom in the Western Legal Tradition. By John WitteJr . Cambridge: Cambridge University Press, 2021. Pp. 316. $110.00 (cloth); $29.99 (paper); $24.00 (digital). ISBN: 9781108429207.
Authors: Little David 
Published: January 2023

AbstractThis review essay registers sincere appreciation for John Witte’s singular contribution to defending the importance of the history and interpretation of rights in the Western tradition, especially as related to Christian thought and practice. It also proposes to amend and refine his approach by highlighting the difference between natural and religious justifications of rights, and by suggesting reasons for favoring the former.
Short-time behavior of solutions to Lévy-driven stochastic differential equations
Authors: Reker Jana 
Published: January 2023

AbstractWe consider solutions of Lévy-driven stochastic differential equations of the form
$\textrm{d} X_t=\sigma(X_{t-})\textrm{d} L_t$
,
$X_0=x$
, where the function
$\sigma$
is twice continuously differentiable and the driving Lévy process
$L=(L_t)_{t\geq0}$
is either vector or matrix valued. While the almost sure short-time behavior of Lévy processes is well known and can be characterized in terms of the characteristic triplet, there is no complete characterization of the behavior of the solution X. Using methods from stochastic calculus, we derive limiting results for stochastic integrals of the form
$t^{-p}\int_{0+}^t\sigma(X_{t-})\,\textrm{d} L_t$
to show that the behavior of the quantity
$t^{-p}(X_t-X_0)$
for
$t\downarrow0$
almost surely reflects the behavior of
$t^{-p}L_t$
. Generalizing
$t^{{\kern1pt}p}$
to a suitable function
$f\colon[0,\infty)\rightarrow\mathbb{R}$
then yields a tool to derive explicit law of the iterated logarithm type results for the solution from the behavior of the driving Lévy process.
Status cues and normative change: How the Academy Awards facilitated Chile's gender identity law
Authors: Schulz Carsten-Andreas , Thies Cameron G. 
Published: January 2023

AbstractThis study explores how the Academy Award for A Fantastic Woman facilitated the adoption of Chile's Gender Identity Law. Approved in 2018 after languishing for over five years in Congress, the law establishes individuals’ right to modify their national identification documents without the need to change their physical appearance or receive prior court authorisation. While trans rights activists extensively lobbied for a law that guaranteed access to gender marker changes, conservatives rejected the initiative, framing their opposition in terms of Christian values and against the ‘gender ideology’ that purportedly informed the bill. We argue that this backlash dissipated in the wake of the award. International recognition made support for trans rights temporarily a matter of national pride, thereby opening a window of opportunity for the approval of the law. The case of Chile's Gender Identity Law illustrates how international status cues can foster normative change by mobilising affect in domestic audiences. It contributes to recent debates on status and domestic political change, and the role that emotion and affect play in world politics.
Crisis, Gender Role Congruency, and Perceptions of Executive Leadership
Authors: Davidson-Schmich Louise K. , Jalalzai Farida , Och Malliga 
Published: January 2023

At a time of pandemics, international economic downturns, and increasing environmental threats due to climate change, countries around the world are facing numerous crises. What impact might we expect these crises to have on the already common perception that executive leadership is a masculine domain? For years, women executives’ ability to lead has been questioned (Jalalzai 2013). However, the outbreak of COVID-19 brought headlines like CNN’s “Women Leaders Are Doing a Disproportionately Great Job at Handling the Pandemic” (Fincher 2020). Do crises offer women presidents and prime ministers opportunities to be perceived as competent leaders? Or do they prime masculinized leadership expectations and reinforce common conceptions that women are unfit to lead? We maintain that people’s perceptions of crisis leadership will depend on whether the crisis creates role (in)congruity between traditional gender norms and the leadership expectations generated by the particular crisis.
Genetic regulation of body size and morphology in children: a twin study of 22 anthropometric traits
Authors: Silventoinen Karri , Maia José , Li Weilong , Sund Reijo , Gouveia Élvio R. , Antunes António , Marques Gonçalo , Thomis Martine , Jelenkovic Aline , Kaprio Jaakko , Freitas Duarte 
Published: January 2023

Abstract
Background
Anthropometric measures show high heritability, and genetic correlations have been found between obesity-related traits. However, we lack a comprehensive analysis of the genetic background of human body morphology using detailed anthropometric measures.

Methods
Height, weight, 7 skinfold thicknesses, 7 body circumferences and 4 body diameters (skeletal breaths) were measured in 214 pairs of twin children aged 3–18 years (87 monozygotic pairs) in the Autonomous Region of Madeira, Portugal. Factor analysis (Varimax rotation) was used to analyze the underlying structure of body physique. Genetic twin modeling was used to estimate genetic and environmental contributions to the variation and co-variation of the anthropometric traits.

Results
Together, two factors explained 80% of the variation of all 22 anthropometric traits in boys and 73% in girls. Obesity measures (body mass index, skinfold thickness measures, as well as waist and hip circumferences) and limb circumferences loaded most strongly on the first factor, whereas height and body diameters loaded especially on the second factor. These factors as well as all anthropometric measures showed high heritability (80% or more for most of the traits), whereas the rest of the variation was explained by environmental factors not shared by co-twins. Obesity measures showed high genetic correlations (0.75–0.98). Height showed the highest genetic correlations with body diameter measures (0.58–0.76). Correlations between environmental factors not shared by co-twins were weaker than the genetic correlations but still substantial. The correlation patterns were roughly similar in boys and girls.

Conclusions
Our results show high genetic correlations underlying the human body physique, suggesting that there are sets of genes widely affecting anthropometric traits. Better knowledge of these genetic variants can help to understand the development of obesity and other features of the human physique.
Approaching optimal entangling collective measurements on quantum computing platforms
Authors: Conlon Lorcán O. , Vogl Tobias , Marciniak Christian D. , Pogorelov Ivan , Yung Simon K. , Eilenberger Falk , Berry Dominic W. , Santana Fabiana S. , Blatt Rainer , Monz Thomas , Lam Ping Koy , Assad Syed M. 
Published: January 2023

AbstractEntanglement is a fundamental feature of quantum mechanics and holds great promise for enhancing metrology and communications. Much of the focus of quantum metrology so far has been on generating highly entangled quantum states that offer better sensitivity, per resource, than what can be achieved classically. However, to reach the ultimate limits in multi-parameter quantum metrology and quantum information processing tasks, collective measurements, which generate entanglement between multiple copies of the quantum state, are necessary. Here, we experimentally demonstrate theoretically optimal single- and two-copy collective measurements for simultaneously estimating two non-commuting qubit rotations. This allows us to implement quantum-enhanced sensing, for which the metrological gain persists for high levels of decoherence, and to draw fundamental insights about the interpretation of the uncertainty principle. We implement our optimal measurements on superconducting, trapped-ion and photonic systems, providing an indication of how future quantum-enhanced sensing networks may look.
Control of acute myeloid leukemia by a trifunctional NKp46-CD16a-NK cell engager targeting CD123
Authors: Gauthier Laurent , Virone-Oddos Angela , Beninga Jochen , Rossi Benjamin , Nicolazzi Céline , Amara Céline , Blanchard-Alvarez Audrey , Gourdin Nicolas , Courta Jacqueline , Basset Alexandra , Agnel Magali , Guillot Franceline , Grondin Gwendoline , Bonnevaux Hélène , Bauchet Anne-Laure , Morel Ariane , Morel Yannis , Chiron Marielle , Vivier Eric 
Published: January 2023

AbstractCD123, the alpha chain of the IL-3 receptor, is an attractive target for acute myeloid leukemia (AML) treatment. However, cytotoxic antibodies or T cell engagers targeting CD123 had insufficient efficacy or safety in clinical trials. We show that expression of CD64, the high-affinity receptor for human IgG, on AML blasts confers resistance to anti-CD123 antibody-dependent cell cytotoxicity (ADCC) in vitro. We engineer a trifunctional natural killer cell engager (NKCE) that targets CD123 on AML blasts and NKp46 and CD16a on NK cells (CD123-NKCE). CD123-NKCE has potent antitumor activity against primary AML blasts regardless of CD64 expression and induces NK cell activation and cytokine secretion only in the presence of AML cells. Its antitumor activity in a mouse CD123+ tumor model exceeds that of the benchmark ADCC-enhanced antibody. In nonhuman primates, it had prolonged pharmacodynamic effects, depleting CD123+ cells for more than 10 days with no signs of toxicity and very low inflammatory cytokine induction over a large dose range. These results support clinical development of CD123-NKCE.
The effects of fertility and synchronization variation on seed production in two Chinese fir clonal seed orchards
Authors: Wang Fang , Zhang Shuaiying , Zhu Peng , Chen Lianghua , Zhu Yuanwei , Yang Changdong , Liu Rendong , Li Fengqing , Huang Xiong , Yang Hanbo 
Published: January 2023

AbstractVariations in fertility and synchronization information is fundamental to seed orchard management. Our objective was to determine clonal variation and stability in strobili production, phenology, synchronization, and seed production in two generation clonal seed orchards (CSO) of Chinese fir. The number of female and male strobili and the phenology of 42 clones in both the 2.0- and 2.5-generation clonal seed orchards were investigated and recorded to calculate the variation and stability of fertility and synchronization. In both seed orchards, an obvious variation in gamete contribution was found among clones, indicating deviation from random mating. Female receptivity was in the pollen shedding stage, which is favorable to pollination. However, low synchronization (mean POij = 0.283) between clones indicated low overlap between female receptivity and pollen shedding. A higher POij value within clones than within outcrossing combinations indicated a high risk of selfing in two seed orchards, particularly for early- and late-flowering clones. The number of female strobili and POij (as female) significantly influence seed production. Overall, fertility and synchronization variation had notable consequences for seed production. Scientific genetic management is indispensable for promoting fertility uniformity and synchronization to obtain maximal genetic gain.
Lumbar ossification of the ligamentum flavum reflects a strong ossification tendency of the entire spinal ligament
Authors: Nakabachi Kazuha , Endo Tsutomu , Takahata Masahiko , Fujita Ryo , Koike Yoshinao , Suzuki Ryota , Hasegawa Yuichi , Murakami Toshifumi , Yamada Katsuhisa , Sudo Hideki , Terkawi Mohamad Alaa , Kadoya Ken , Iwasaki Norimasa 
Published: January 2023

AbstractPatients with ossification of the ligamentum flavum (OLF) in the lumbar spine may be at high risk of developing concomitant ossification of the entire spinal ligament, but the etiology remains unclear. We investigated the propensity for spinal ligament ossification in asymptomatic subjects with lumbar OLF using the data of 595 Japanese individuals receiving medical check-ups, including computed tomography (CT) scanning. The severity of OLF (total number of intervertebral segments with OLF) of the entire spine on CT was quantified using an OLF index. Subjects with OLF were grouped according to this index: localized OLF (n = 138), intermediate OLF (n = 70), and extensive OLF (n = 31). The proportion of subjects with lumbar OLF increased with increasing OLF index (localized 13.7%, intermediate 41.4%, and extensive 70.9%). Multiple regression analysis found that lumbar OLF index was associated with thoracic OLF index, and co-existence of ossification of the posterior longitudinal ligament (OPLL) of the thoracic and lumbar spine. This study showed that subjects with more multilevel lumbar OLF were more likely to develop multilevel thoracic OLF and to have coexisting OPLL. Patients with lumbar OLF may be a distinctive subgroup with a strong tendency to ossification of the entire spinal ligament.
CART model to classify the drought status of diverse tomato genotypes by VPD, air temperature, and leaf–air temperature difference
Authors: Fang Shih-Lun , Tu Yuan-Kai , Kang Le , Chen Han-Wei , Chang Ting-Jung , Yao Min-Hwi , Kuo Bo-Jein 
Published: January 2023

AbstractRegular water management is crucial for the cultivation of tomato (Solanum lycopersicum L.). Inadequate irrigation leads to water stress and a reduction in tomato yield and quality. Therefore, it is important to develop an efficient classification method of the drought status of tomato for the timely application of irrigation. In this study, a simple classification and regression tree (CART) model that includes air temperature, vapor pressure deficit, and leaf–air temperature difference was established to classify the drought status of three tomato genotypes (i.e., cherry type ‘Tainan ASVEG No. 19’, large fruits breeding line ‘108290’, and wild accession ‘LA2093’). The results indicate that the proposed CART model exhibited a higher predictive sensitivity, specificity, geometric mean, and accuracy performance compared to the logistic model. In addition, the CART model was applicable not only to three tomato genotypes but across vegetative and reproductive stages. Furthermore, while the drought status was divided into low, medium, and high, the CART model provided a higher predictive performance than that of the logistic model. The results suggest that the drought status of tomato can be accurately classified by the proposed CART model. These results will provide a useful tool of the regular water management for tomato cultivation.
Using identification method to modelling short term luminous flux depreciation of LED luminaire to reducing electricity consumption
Authors: Sikora Roman , Markiewicz Przemysław , Korzeniewska Ewa 
Published: January 2023

AbstractReducing electricity consumption is currently one of the most significant global issues. Luminaires and light sources are characterised by relatively low rated power values. However, due to their high number, they account for a noticeable share of the total volume of electricity consumption. When the LED lamp/luminaire is switched-on, it emits a higher luminous flux and receives more power from the mains supply than when the thermal conditions have stabilized. This phenomenon is called short-term luminous flux depreciation. The lighting design process on photometric data obtained for steady-state operating conditions is based, on once the luminous flux has stabilized. Therefore, it is possible to design the control algorithm of the LED luminaire in such a way as to reduce this phenomenon, which will result in measurable savings of electrical energy. The paper proposes the use of a method to identify the short-term luminous flux depreciation of LED luminaires. The model was then used to simulate the operation of a control algorithm limiting the phenomenon of short-term luminous flux depreciation.
Electric field distribution around asymmetric agglomerate model reconstructed from FIB–SEM images of epoxy nanocomposite
Authors: Tagawa Kazuma , Kurimoto Muneaki , Sawada Toru , Yoshida Shigeyoshi , Umemoto Takahiro , Muto Hirotaka 
Published: January 2023

AbstractThis study focussed on determining the electric field distribution formed by asymmetric agglomerates in order to elucidate the mechanism by which large agglomerates reduce the dielectric breakdown strength of nanocomposites. Epoxy nanocomposite sample was prepared by adding 2.5 vol% of TiO2 nanoparticles with a primary particle size ranging from 30 to 50 nm. The three‐dimensional (3D) structure of the epoxy nanocomposites with a thickness of 5 μm was analysed via focussed ion beam and scanning electron microscopy. The 3D reconstruction was performed using 250 observation images, and a 3D model of the particle in the observational range was obtained. The electric field distribution for the 3D model of the agglomerate with the largest size was determined using the finite element method. In addition, we constructed a calculation model that effectively accommodate changes in the direction of the applied electric field. Subsequently, we examined the changes in the maximum electric field intensity around the agglomerate.
Individuelle Behandlung bei Glaukompatienten mit einem Diabetes mellitus
Authors: Luebke Jan 
Published: January 2023

ZusammenfassungDas Glaukom und der Diabetes mellitus sind 2 in Europa und weltweit häufig vorkommende chronische Erkrankungen, die einer intensiven Therapie bedürfen. Pathophysiologisch werden
verschiedene Mechanismen diskutiert, die vor allem beim Vorliegen eines Diabetes mellitus die Entstehung eines Glaukoms begünstigen. Die medikamentöse und chirurgische Einstellung des
Augeninnendruckes ist bei Patienten mit einem Diabetes mellitus mit einigen Einschränkungen verbunden, so zeigen die filtrierenden Eingriffe geringere Erfolgsraten als bei nicht an Diabetes
erkrankten Glaukompatienten. Neben der rein augenheilkundlich-endokrinologischen Therapie sollte ebenfalls die psychologische Belastung durch 2 chronische Erkrankungen bedacht und in den
individuellen Therapieplan aufgenommen werden.