bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hepatitis E virus seroprevalence among employees in catering and public place industries in Nanjing, China
Authors: Guo Jinlei , Zhang Juansheng , Li Lingling , Gao Xingli 
Published: July 2023

Abstract
This study aimed to assess the prevalence of anti-hepatitis E virus (HEV) immunoglobulin (Ig) M and elevated serum alanine aminotransferase (ALT) levels among employees in catering and public place industries. Blood samples were collected between January and December 2020 from 26,790 employees working in the Qinhuai district of Nanjing, China. Anti-HEV IgM in the serum samples was tested by the capture ELISA method and ALT was tested by the IFCC method. Samples positive for anti-HEV IgM or with ALT levels over 200 U/L were subjected to PCR screening of HEV RNA. The overall seroprevalence of anti-HEV IgM was 0.41%, and the seroprevalence was slightly higher in males (0.47%) than in females (0.37%); however, the difference was not substantial (p = 0.177). Seroprevalence of anti-HEV IgM increased with age, reaching its peak level after 48 years of age. The prevalence of elevated ALT levels was 4.24%, and males exhibited a higher prevalence than females (6.78% vs 2.65%, p < 0.001). Prevalence of elevated ALT levels differed in age groups and the 26–36-year-old group had the highest rate of elevated ALT levels. Employees with elevated ALT levels had a higher prevalence of positive anti-HEV IgM than those with normal ALT (0.57% vs 0.31%, p < 0.001). Positive HEV RNA was detected in one anti-HEV IgM-negative employee with ALT higher than 200 U/L. In our study, all the HEV RNA-positive and IgM-positive individuals are asymptomatic, and a combination of ALT tests, serological methods, and molecular methods is recommended to screen asymptomatic HEV carriers and reduce the risk of transmission.
Improving the measurement of biblical interpretation in social science research
Authors: Mockabee Stephen T. , Lewis Andrew R. 
Published: July 2023

AbstractAsking about people's views of the Bible in a single survey question has become the prevailing way to understand the mass public's religious beliefs. Nevertheless, the standard survey items raise questions about what is being measured. The questions used to measure one's views of the Bible are often double-barreled and leave considerable room for interpretation. In this paper, we assess the measurement error in the standard three-category question from the American National Election Study (ANES) by developing new items to gauge what it might mean to a respondent to select one of the three options in the standard Bible question. Using original data from two online surveys, we demonstrate that there is substantial measurement error in the standard ANES item. Analyses also show that our new items predict responses to the standard ANES item and are potent predictors of political attitudes—often performing better than the widely used three-category question.
Role of N6-methyladenosine RNA modification in gastric cancer
Authors: Ding Si-Qi , Zhang Xue-Ping , Pei Jun-Peng , Bai Xiao , Ma Jin-Jie , Zhang Chun-Dong , Dai Dong-Qiu 
Published: July 2023

AbstractN6-methyladenosine (m6A) RNA methylation is the most prevalent internal modification of mammalian messenger RNA. The m6A modification affects multiple aspects of RNA metabolism, including processing, splicing, export, stability, and translation through the reversible regulation of methyltransferases (Writers), demethylases (Erasers), and recognition binding proteins (Readers). Accumulating evidence indicates that altered m6A levels are associated with a variety of human cancers. Recently, dysregulation of m6A methylation was shown to be involved in the occurrence and development of gastric cancer (GC) through various pathways. Thus, elucidating the relationship between m6A and the pathogenesis of GC has important clinical implications for the diagnosis, treatment, and prognosis of GC patients. In this review, we evaluate the potential role and clinical significance of m6A-related proteins which function in GC in an m6A-dependent manner. We discuss current issues regarding m6A-targeted inhibition of GC, explore new methods for GC diagnosis and prognosis, consider new targets for GC treatment, and provide a reasonable outlook for the future of GC research.
Library of rough hailstone backscattering coefficients at 2.8 GHz
Authors: Mirkovic Djordje , Zrnic Dusan S. 
Published: July 2023

AbstractThe rough hailstone scattering library is created to fill the need for results of non-spheroidal hailstone backscattering characteristics. The listed backscattering coefficients at the S-band (2.8 GHZ) are specifically tailored for computing the polarimetric variables. The National Weather Service’s radar operates in this band; hence the library is pertinent to those studying hail in the USA. The library contains several axis ratios and a range of hail sizes from 5 mm to 100 mm. Moreover, hailstone surface roughness is expressed as a percentage of the equatorial diameter. Our computational electromagnetic approach to modeling hailstones is compared with typically employed simpler methods. The polarimetric variables calculated using our models can be compared to observations. Furthermore, we illustrate the potency of the CEM approach to hydrometeors with extreme axis ratios for which simpler methods (i.e., the T-matrix) fail.
Le débriefing comme clé de l’accompagnement réflexif en formation et en pratique de l’éducation thérapeutique du patient
Authors: Cavalli Euvrard Glori , Poteaux Nicole 
Published: July 2023

Contexte : La formation des soignants à l’éducation thérapeutique du patient (ETP) vise l’amélioration des compétences pédagogiques et relationnelles pour soutenir les personnes affectées par des maladies chroniques. Les formateurs construisent leurs formations selon le principe d’isomorphisme pédagogique qui présuppose que les activités de formation, et notamment le débriefing, peuvent se transférer de la formation à la pratique clinique. But : Observer si le principe d’isomorphisme pédagogique est pertinent et transposable dans la pratique clinique éducative, y compris sur les compétences mobilisées lors du débriefing. Méthodes : Étude qualitative fondée des entretiens semi-dirigés à destination d’une part des formateurs et d’autre part des participants. Les questions portaient sur l’expérience de formation et sur la pratique éducative avec les patients. Les participants à l’étude étaient des professionnels de santé exerçant une activité clinique et ayant vécu une formation dite de 40 h en ETP. Résultats : Douze entretiens incluant six formateurs et six participants ont été réalisés durant le premier trimestre 2020. Tous les participants à l’étude reconnaissent la pertinence de l’isomorphisme pédagogique dans la formation en ETP. Ils décrivent des points communs entre le débriefing de formation et l’étape éducative de suivi avec les patients (« évaluer avec ») car dans les deux cas le professionnel accompagne la réflexivité. Les formateurs sont unanimes sur l’intérêt du débriefing pour mettre en perspective l’expérience mais leurs avis divergent sur la rétroaction. En clinique, les professionnels de santé ne partagent pas de rétroaction avec leur patient. Conclusion : Derrière le débriefing se joue l’accompagnement de la réflexivité. Cette compétence transversale mériterait une approche explicite par les formateurs. Un débriefing du débriefing à distance de l’expérience des jeux de rôle permettrait aux participants de se l’approprier et le transférer.
Dans quelle mesure les examens cliniques objectifs structurés (ECOS) sont-ils un outil valide pour l’évaluation des performances cliniques à la fin du second cycle des études médicales ? Analyse d’une expérience lilloise selon le modèle de Kane
Authors: Ficheux Guillaume , Niguet Jean-Paul , Van der Linden Thierry , Bulckaen Hélène , Charkaluk Marie-Laure , Perimenis Pierrette , Roy Saint-Georges Françoise , Hernandez Élodie , Lorenzo Mathieu 
Published: July 2023

Contexte et problématique : La réforme du second cycle des études médicales en France implique la mise en place de nouvelles modalités évaluatives parmi lesquelles des examens cliniques objectifs structurés (ECOS), outil standardisé d’évaluation de la performance clinique en environnement simulé. L’interprétation des scores issus de ces ECOS nationaux aura un impact majeur sur la formation des futurs médecins. Objectifs : Notre étude vise à montrer comment l’analyse de la validité de l’interprétation des scores d’un examen ECOS local selon le modèle de Kane peut fournir des données pour améliorer les ECOS nationaux. Méthodes : Cent sept étudiants en sixième année d’études ont participé en mars 2020 à une session d’ECOS. Les quatre inférences du modèle de Kane ont été appliquées à cet examen pour analyser la validité de l’interprétation des scores. Les scores obtenus aux ECOS, les évaluations de stage et le rang de classement aux épreuves classantes nationales informatisées (ECNi) ont notamment été colligés et analysés. Résultats : La validité de l’interprétation des scores des ECOS semblait globalement bonne. Quelques limites en termes de validité ont été identifiées dans les inférences de notation et de généralisation. Il n’y avait pas de différence significative de notation entre les évaluateurs. Il existait des corrélations statistiques significatives entre les scores aux ECOS et les évaluations en stage, ainsi qu’entre les scores aux ECOS et le rang de classement aux ECNi. Conclusion : Si la validité de l’interprétation des scores des ECOS semblait bonne dans le contexte de l’étude, nos données suggèrent des axes d’amélioration qui devront faire l’objet d’une attention particulière pour la mise en place d’examens à enjeu élevé tels que les ECOS nationaux en France dans les prochaines années. Cette étude illustre l’intérêt du modèle de Kane pour identifier de tels axes d’amélioration d’un dispositif d’évaluation des apprentissages.
The Riddle as a Representative of a Small Folklore Genre in Russian and English Languages
Authors: Mantsaeva A.N. , Usmanov T.I. , Magomadova T.D. 
Published: July 2023

The research is dedicated to the texts of riddles in diverse languages, in particular Russian and English, as representatives of the small folklore genre. The authors note that the main task of the riddle genre is to familiarize the bearer of folk culture with the folklore system. One of the features of modeling reality in the genre under study is the image of objects from their pragmatic features, as well as external characteristics.
One of the specific features of the riddle genre is a special choice of objects of reality belonging to the realities of the material world, and having external characteristics that perform important functions necessary for a person. Such requirements for the objects of reality are conditioned by the task of the genre itself, which are teaching the categorization of reality, highlighting important from the point of view of pragmatics objects and phenomena that contribute to the adaptation of the individual in society. The article analyzes riddles in Russian and English from the point of view of reflecting the linguistic picture of the world in them; reveals the meaningful and pragmatic features of riddles in multi-system languages; determines their genre-language organization. It is proved that the riddle is an element of the language game; the phenomenon of the language game in riddles in different languages is traced and enigmatic works with elements of wordplay in Russian and English are characterized).
Radiofrequency Ablation in Primary Aldosteronism
Authors: Lee Yun-Ni , Drake William Martyn 
Published: July 2023

AbstractThe radiofrequency ablation (RFA) technique has been extensively used in the
treatment of primary malignancies and metastases and has been recently deployed
for the treatment of unilateral primary aldosteronism (PA) as an alternative to
whole unilateral adrenalectomy.Current evidence comparing RFA with unilateral adrenalectomy in the treatment of
PA so far has been variable, with studies being retrospective and small-scale,
but it remains a very attractive option as a potentially less invasive treatment
option compared to adrenalectomy.This review article describes the procedure, and provides evidence and the
possible future direction of RFA in the treatment of unilateral PA.
A fair share? Animal health actors and resources in One Health initiatives: A multisite case study in Ethiopia and Pakistan
Authors: Braam Dorien H. , Tasker Alex , Parravani Ellie , Saville Klara 
Published: July 2023

Abstract
Increased outbreaks of zoonotic diseases with pandemic potential and the growing threat of antimicrobial resistance have stimulated the uptake and use of One Health approaches across the globe. Collaborative, multisectoral, and transdisciplinary approaches are vital to the effective response to health challenges; however, within One Health initiatives, animal and environmental health voices often remain secondary to human health. This article presents the findings of a transdisciplinary research project investigating the roles and contributions of animal health in One Health initiatives. We combined a multisite case study approach with a literature review, and conducted 22 semi-structured key informant interviews with animal health and One Health experts, with a focus on Ethiopia and Pakistan. Key themes explored were the nature of the animal health sector, animal health workforce, veterinary medicines and vaccines, and coordination and collaboration. Results were triangulated with existing primary and secondary data, reviewed by key stakeholders in Ethiopia and Pakistan, and tested with members of the Action for Animal Health (A4AH) coalition. We found that while One Health has become more interdisciplinary and inclusive at a global level, there remain significant challenges in operationalizing the approach at national and subnational levels. Gaps in governance, political will, and capacity undermine the inclusion of animal health in One Health structures. Power and resources are distributed unequally across One Health coalitions, echoing observations that acknowledge the crucial role of communities in supporting the provision of essential services, while their knowledge and experiences often remain excluded from project and policy development. We conclude that stronger multilevel linkages and engagement between animal health and other sectors are vital to support the implementation of inclusive, well-resourced, and effective One Health approaches.
Optimization of squeeze casting process parameters on mechanical properties of SiCp reinforced LM25 composites through Taguchi technique
Authors: S Fazlul Rahman , J Anburaj , Chanakyan C 
Published: July 2023

Abstract
The aim of the present work is to examine the influence of processing parameters on fabricated composites of LM25 alloy with SiC particle reinforcement through a squeeze casting technique. The following process parameters, like stirring speed from 550 to 750 rpm, SiCP (4 wt% to 8 wt %), and melting temperatures (from 600 to 700 °C) were employed. Then, the processed composites were subjected to microscopy analysis and mechanical tests to ascertain their metallurgical and mechanical properties. SEM micrographs of an LM 25 composite sample show better bonding of SiC particles with matrix, which is due to homogeneous dispersion of SiC particles in the stir casting process. The maximum tensile strength (211 MPa) and hardness (91 Hv) were achieved on the composite samples with processing parameters of 750 rpm stirring speed, 8% SiC proportions, and 650 °C melting temperature, respectively. From the design of the experiment by the Taguchi method, it is observed that the stirring speed plays a significant role in achieving a better distribution of SiC particles in the composite samples than other parameters like SiC weight ratios and the melting temperature of the alloy.
Dirac-Born-Infeld counter-term and black hole thermodynamics
Authors: Jatkar Dileep P , Moitra Upamanyu 
Published: July 2023

Abstract
We revisit the Dirac-Born-Infeld–like boundary counter-term for the four-dimensional theory of gravity. We show that it correctly executes complete background subtraction for both asymptotically Anti-de Sitter and asymptotically flat geometries. With an appropriate choice of ensemble, we reproduce dyonic black hole thermodynamics with both types of asymptotics by studying local thermodynamics on the cut-off surface.
Performance of prototype dual gain multilayer thick gas electron multiplier with high-intensity heavy-ion beam injections in low-pressure hydrogen gas
Authors: Iwamoto Chihiro , Ota Shinsuke , Kojima Reiko , Tokieda Hiroshi , Hayakawa Seiya , Mizoi Yutaka , Gunji Taku , Yamaguchi Hidetoshi , Imai Nobuaki , Dozono Masanori , Nakajima Ryo , Beliuskina Olga , Michimasa Shin’ichiro , Yokoyama Rin , Kawata Keita , Suzuki Daisuke , Isobe Tadaaki , Zenihiro Juzo , Matsuda Yohei , Okamoto Jun , Murakami Tetsuya , Takada Eiichi 
Published: July 2023

Abstract
A prototype Dual Gain Multilayer Thick Gas Electron Multiplier (DG-M-THGEM) with an active area of 10 cm × 10 cm was manufactured aiming at the production of a large-volume active-target time projection chamber which can work under the condition of high-intensity heavy-ion beam injections. The DG-M-THGEM has an alternating structure of electrodes and insulators. Effective gas gains of two regions, which are called beam and recoil regions, are separately controlled. Performance of the prototype DG-M-THGEM in hydrogen gas at a pressure of 40 kPa was evaluated. Irradiating a 132Xe beam, an effective gas gain lower than 100 with a charge resolution of 3% was achieved in the beam region while an effective gas gain of 2000 was maintained in the recoil region. Position distributions of measured charges along the beam axis were investigated in order to evaluate gain uniformity in the high-intensity beam injection. The gain shift was estimated by simulations considering space charges in the drift region. The gain shift was suppressed within 3% even at the beam intensity of 2.5 × 106 particles per second.
CaSR modulates proliferation of the superficial zone cells in temporomandibular joint cartilage via the PTHrP nuclear localization sequence
Authors: Zhou Peng , Yang Hongxu , Zhang Mian , Liu Jinqiang , Yu Jia , Yu Shibin , Liu Qian , Zhang Yuejiao , Xie Mianjiao , Xu Xiaojie , Liu Jiguang , Wang Meiqing 
Published: July 2023

AbstractThe superficial zone cells in mandibular condylar cartilage are proliferative. The present purpose was to delineate the relation of calcium‐sensing receptor (CaSR) and parathyroid hormone‐related peptide nuclear localization sequence (PTHrP87‐139), and their role in the proliferation behaviors of the superficial zone cells. A gain‐ and loss‐of‐function strategy were used in an in vitro fluid flow shear stress (FFSS) model and an in vivo bilateral elevation bite model which showed mandibular condylar cartilage thickening. CaSR and PTHrP87‐139 were modulated through treating the isolated superficial zone cells with activator/SiRNA and via deleting CaSR or parathyroid hormone‐related peptide (PTHrP) gene in mice with the promoter gene of proteoglycan 4 (Prg4‐CreERT2) in the tamoxifen‐inducible pattern with or without additional injection of Cinacalcet, the CaSR agonist, or PTHrP87‐139 peptide. FFSS stimulated CaSR and PTHrP expression, and accelerated proliferation of the Prg4‐expressing superficial zone cells, in which process CaSR acted as an up‐streamer of PTHrP. Proteoglycan 4 specific knockout of CaSR or PTHrP reduced the cartilage thickness, suppressed the proliferation and early differentiation of the superficial zone cells, and inhibited cartilage thickening and matrix production promoted by bilateral elevation bite. Injections of CaSR agonist Cinacalcet could not improve the phenotype caused by PTHrP mutation. Injections of PTHrP87‐139 peptide rescued the cartilage from knockout of CaSR gene. CaSR modulates proliferation of the superficial zone cells in mandibular condylar cartilage through activation of PTHrP nuclear localization sequence. Our data support the therapeutic target of CaSR in promoting PTHrP production in superficial zone cartilage.
Donor Diabetes and Steatosis Affects Recipient Survival Following Liver Transplantation Based on Etiology of Liver Cirrhosis
Authors: Lim Wen Hui , Ng Cheng Han , Tan Darren Jun Hao , Xiao Jieling , Fu Clarissa Elysia , Ong Christen , Koh Benjamin , Chung Charlotte , Tan Shi Ni , Wong Zhen Yu , Mitchell Kimberly , Joseph Ayana Andrews , Tseng Michael , Syn Nicholas , Mak Lung Yi , Fung James , Huang Daniel Q. , Muthiah Mark , Tan Eunice X.X. , Siddiqui Mohammad Shadab 
Published: July 2023

Background.
Liver transplantation (LT) offers patients with decompensated cirrhosis the best chance at long-term survival. With the rising prevalence of diabetes, further clarity is needed on the impact of receiving a liver allograft from a donor with diabetes on post-LT outcomes. This study aims to evaluate the impact of donor diabetes on clinical outcomes after LT.

Methods.
This is a retrospective analysis of the United Network for Organ Sharing registry data of LT recipients from January 1, 2000, to December 31, 2021. Outcomes analysis was performed using Cox proportional model for all-cause mortality and graft failure. Confounding was reduced by coarsened exact matching causal inference analysis.

Results.
Of 66 960 donors identified, 7178 (10.7%) had diabetes. Trend analysis revealed a longitudinal increase in the prevalence of donor diabetes (P < 0.001). Importantly, donor diabetes was associated with increased all-cause mortality (hazard ratio [HR]: 1.13; 95% confidence interval [CI], 1.07-1.19; P < 0.001) and graft failure (HR: 1.16; 95% CI, 1.11-1.22; P < 0.001). Receiving donor organ with diabetes reduced graft survival in patients who received LT for nonalcoholic steatohepatitis cirrhosis (HR: 1.26; 95% CI, 1.13-1.41; P < 0.001) but not other etiologies of cirrhosis.

Conclusions.
Donor diabetes was associated with worse outcomes post-LT, particularly in patients receiving LT for nonalcoholic steatohepatitis cirrhosis. Future studies are needed to better understand the mechanism underlying this association to develop better risk stratification and clinical practice to improve the outcomes of the transplanted patients.
Asymmetric stimulus representations bias visual perceptual learning
Authors: Laamerad Pooya , Awada Asmara , Pack Christopher C. , Bakhtiari Shahab 
Published: July 2023

AbstractThe primate visual cortex contains various regions that exhibit specialization for different stimulus properties, such as motion, shape, and color. Within each region there is often further specialization, such that particular stimulus features, such as horizontal and vertical orientations, are overrepresented. These asymmetries are associated with well-known perceptual biases, but little is known about how they influence visual learning. Most theories would predict that learning is optimal, in the sense that it is unaffected by these asymmetries. But other approaches to learning would result in specific patterns of perceptual biases. To distinguish between these possibilities, we trained human observers to discriminate between expanding and contracting motion patterns, which have a highly asymmetrical representation in visual cortex. Observers exhibited biased percepts of these stimuli, and these biases were affected by training in ways that were often suboptimal. We simulated different neural network models and found that a learning rule that involved only adjustments to decision criteria, rather than connection weights, could account for our data. These results suggest that cortical asymmetries influence visual perception and that human observers often rely on suboptimal strategies for learning.