bluuebunny/crossref_metadata_2025_split huggingface dataset:
The comparison of expressed emotion of parents of individuals with fragile X syndrome to other intellectual disabilities
Authors: Coleman Jeanine , Thompson Talia , Riley Karen , Allen Korrie , Michalak Claire , Shields Rebecca , Berry‐Kravis Elizabeth , Hessl David 
Published: January 2023

AbstractBackgroundParenting children and young adults with intellectual disabilities, including individuals with fragile X syndrome and Down syndrome, is challenging, joyful, and complicated. Exploring how parents talk about their children, and the quality of the parent/child relationship can provide insight into the home environment and interactional patterns of the family.MethodExpressed emotion (EE) is a measurement of a family's emotional climate based on a parent or caregiver's report of warmth, emotional overinvolvement, hostility, and criticism. The purpose of this study was to describe EE for a sample of parents of individuals with intellectual disabilities and to determine any differences in EE amongst individuals within subgroups. Based on previous research about fragile X syndrome and family systems, we hypothesized that there would be significant differences between the disability groups (higher EE in families with children/young adults with fragile X syndrome).ResultsResults showed relatively high proportions of EE across groups of individuals with intellectual disabilities, however, there were no significant differences between the subgroups. Null findings suggest that differences in EE may not relate directly to a child's specific genetic condition. Rather, increased EE in caregiver populations may simply reflect well‐documented stressors related to stigma, caregiver burden, and limited community supports. Critical statements were infrequent, however, over half of the participants reported dissatisfaction with their situation, and many were categorized as having emotional overinvolvement, as measured by frequent statements of intense worry and self‐sacrifice.ConclusionFindings point to potential utility in family‐level interventions focused on providing structured caregiver therapy to manage excessive worry and grief related to a diagnosis of intellectual disability, and respite care to encourage caregiver independence and pursuit of personal care.
A trait‐based approach to marine island biogeography
Authors: Ferrari Débora S. , Floeter Sergio R. , Leprieur Fabien , Quimbayo Juan P. 
Published: January 2023

AbstractAimThe Island Biogeography Theory (IBT) and its multiple extensions explain species diversity patterns in insular systems. However, how these theories can predict the functional diversity patterns in island systems remains challenging. Here, we evaluated the predictions of the IBT, the General Dynamic Theory of Oceanic Island Biogeography (GDM) and the Glacial‐sensitive model of Island Biogeography (GSM) considering the functional diversity of reef fishes on islands.LocationTropical oceanic islands.TaxonActinopterygii.MethodWe combined literature data and online repositories to gather occurrence data and traits of reef fish species for 72 tropical oceanic islands. We then calculated five functional diversity indices (functional richness ‘FRic’, functional evenness ‘FEve’, functional divergence ‘FDiv’, functional over‐redundancy ‘FOR’ and functional vulnerability ‘FVul’). We used generalized additive mixed models to explore relationships among species richness and functional indices. Furthermore, we built Bayesian models to evaluate relationships between the functional diversity indices and several island features (isolation from the nearest reef, past and present reef area, and geological age) and two metrics that reflect the potential influence of Quaternary climatic changes (isolation from Quaternary refugia) and historical contingency (isolation from biodiversity centres).ResultsWe observed higher levels of FRic, FDiv and FOR on the Indo‐Pacific islands, whereas FEve and FVul showed higher values on the Atlantic and Eastern Pacific islands. We identified positive relationships between FRic, FDiv and FOR with species richness but negative relationships with FEve and FVul. We found that past and present reef areas best explained the variation in functional diversity among islands.Main ConclusionsThe functional diversity of reef fishes on oceanic islands showed a longitudinal gradient, which can be explained by differences in the evolutionary history among marine regions. Furthermore, past and present reef areas were found to be the best predictors of reef fish functional diversity on oceanic islands, extending the IBT, GDM and GSM for marine organisms within a trait‐based framework.
Flotillin‐1 is a prognostic biomarker for glioblastoma and promotes cancer development through enhancing invasion and altering tumour microenvironment
Authors: Wang Ran , Chen Zhikang , Zhang Yi , Xiao Shihan , Zhang Wuming , Hu Xianqin , Xiao Qun , Liu Qing , Wang Xiangyu 
Published: January 2023

AbstractFlotillin‐1(FLOT1) has long been recognized as a tumour‐promoting gene in several types of cancer. However, the expression and function of FLOT1 in glioblastomas (GBM) has not been elucidated. Here, in this study, we find that the expression level of FLOT1 in GBM tissue was much higher than that in normal brain, and the expression was even higher in the more aggressive subtypes and IDH status of glioma. Kaplan–Meier survival revealed that high FLOT1 expression is closely associated with poor outcome in GBM patients. FLOT1 knockdown markedly reduced the proliferation, migration and invasiveness of GBM cells, while FLOT1 overexpression significantly increases GBM cell proliferation, migration and invasiveness. Mechanistically, FLOT1 expression may play a potential role in the microenvironment of GBM. Therefore, FLOT1 promotes GBM proliferation and invasion in vitro and in vivo and may serve as a biomarker of prognosis and therapeutic potential in the fight against GBM.
Fatty acid–binding protein genes in gilthead seabream: molecular cloning and nutritional regulation under low water temperatures
Authors: Taşbozan Oğuz , Erbaş Celal , Bayır Mehtap , Özdemir Erdal , Arslan Gökhan , Bayır Abdulkadir 
Published: January 2023

AbstractThe molecular characteristics and tissue disruption of 10 fatty acid–binding protein (fabp) genes in gilthead seabream (Sparus aurata) were investigated, and their expression levels were found in the fish fed diets with different vegetable oil (VO) sources, which may explore the potential function of fabp genes in S. aurata. For this purpose, the open reading frames of fabp genes involved in the transport and ß‐oxidation of fatty acids (FA) were molecularly cloned and characterized. S. aurata was then exposed to a two‐staged feeding trial (the grow‐out period following a wash‐out period) at low water temperatures. In the grow‐out period, the fish were fed diets containing 50% and 100% ratios of various VOs for 60 days, and in the wash‐out period, the fish were fed a diet containing 100% fish oil (FO) for 30 days. It has been determined that (a) S. aurata and vertebrate fabp/FABP genes are orthologues; (b) spatio‐temporal differences in tissue‐specific patterns of fabp genes differ importantly; for instance, the difference between the highest and lowest values reaches 13 × 105‐fold in the fabp10a; and (c) VO‐based diets upregulated fabp transcript levels in the liver and muscle with some exceptions, such as liver fabp11a and muscle fabp7a. Gene expressions of only the hepatic fabp7b and fabp10a genes were diminished at the end of the wash‐out period. In this study, the authors provide further evidence that dietary FAs affect fabp mRNA expressions in S. aurata. This might be useful in the nutritional control of fabp genes to maintain lipid homeostasis in marine fish fed VO‐based diets at low water temperatures.
Age, growth, reproduction and status of resource development of Ptychidio jordani, a critically endangered freshwater fish in the Hongshui River, China
Authors: He Jiayang , Wu Zhiqiang , Huang Liangliang , Sun Yangyan , Wang Dongjie , Lin Yong , He Anyou , Feng Jie , Liu Hao 
Published: January 2023

AbstractThe age, growth, reproduction and resource development status of Ptychidio jordani, as a critically endangered freshwater fish in the Hongshui River, China, was studied in this work. A total of 525 specimens were collected monthly using the cages and gillnets from October 2021 to September 2022 in the Hongshui River. The scale was used for age determination, and the maximum age for both female and male was estimated to be 5 years and 3 years, respectively. Female and male P. jordani showed different growth patterns, which were expressed as Lt = 261.3 (1‐e−0.4885(t−0.1476)) and Lt = 251.2 (1‐e−0.4758(t+0.9643)), respectively. The overall sex ratio was 1:0.47 (female:male). Female attained sex maturity at 2.34 years (192 mm body length). Month variation of the gonad somatic index indicated that the spawning period occurred from April to October. The absolute fecundity was estimated at 9046 ± 3434 eggs per individual, and the relative fecundity was 38.08 ± 15.77 eggs per gram. The exploitation rate of female and male was 0.233 and 0.495, which indicated that P. jordani was not overfishing. This study provided data on the key life‐history traits of P. jordani, which has not been known previously and is essential for conservation strategy and policy development.
Trends in abundance indices derived from commercial fisheries for priority marine stocks in the Azores
Authors: Santos Régis , Medeiros–Leal Wendell , Pinho Mário 
Published: January 2023

AbstractLarge‐scale assessments of fish and shellfish populations may be valuable for identifying the impacts of fishing pressure on stocks, but they are rarely possible due to a lack of long‐term datasets. In this study, a two‐part mixed‐effect model for lognormal data was used to obtain historical abundance indices for 16 priority fish and shellfish stocks in the Azores region derived from catch per unit effort (kg per day at sea per vessel) and landing per unit effort (kg per landing per vessel). This data was obtained over the past 30 years under the EC Data Collection Framework and, in addition to information on effort and catch, included details about the fishing operation such as quarter, vessel length and fishing gear. This information was analysed to investigate how abundance indices changed over the years, verify if trends from different data sources were different and, if possible, relate these results to the population and fishery dynamics. The abundance indices derived from both datasets were generally in agreement with each other. Declining trends have been observed for some commercially important species, such as forkbeard Phycis phycis, European conger Conger conger, parrotfish Sparisoma cretense, red scorpionfish Scorpaena scrofa, offshore rockfish Pontinus kuhlii, common spiny lobster Palinurus elephas, splendid alfonsino Beryx splendens and alfonsino B. decadactylus, which is concerning because they are particularly slow‐growing, long‐lived and have low natural mortality, making them susceptible to overfishing. The results of this study are very important and should help future stock assessment and management initiatives.
Effects of heating process on 3D printing properties of Pennahia argentata surimi: Water distribution, gel formation, rheology, chemical bonds
Authors: Li Gaoshang , Zhan Junqi , Hu Zhiheng , Huang Jiayin , Yuan Chunhong , Takaki Koichi , Hu Yaqin , Yao Qian 
Published: January 2023

AbstractThe gel is an important factor in 3D printability of Pennahia argentata surimi. While surimi gel is sensitive to temperature and influenced by chemical bonds changes. Hence, preheating effects on printing and material properties of surimi were investigated. Results shown hydrogen bonds and ionic bonds contents in surimi under different heating conditions decreased about 20%–90%. Meanwhile, hydrophobic force and disulfide bonds increased about 0.2–6 times. These changes formed more gel, as well as 6.5% at most immovable water transferred into free water which enhanced texture properties and made solid properties of rheology in surimi dominant. This phenomenon occurred significantly in temperature range of gel formation (35–40°C, 90°C) while became extinct at 45°C with 10–30 min due to gel degradation. These made surimi by heating exhibit strong mechanical strength, which is conducive to forming process when printing after extrusion. However, if they occurred before extrusion, these could increase extrusion difficulty to make filamentous materials be broken easily after extrusion, weakening printing effect. Hence, preheating of surimi before extrusion was not suitable for 3D printing. While short‐time heating during or after extrusion might be more appropriate for printed surimi, promoting the application of surimi in 3D printing technology.Practical Applications3D printing is a new technology in food processing that refers the process of connecting or curing materials to form 3D objects by continuously adding layers of materials. Surimi is one of the suitable materials which can promote the process of printing. While the material properties of surimi are affected by temperature that influences the printing effects. The purpose of this study was to investigate the effects of different temperatures on the material properties of Pennahia argentata surimi, and determine the suitable heating process of printed surimi products. These results could promote the application of 3D printing technology in surimi processing.
Cellulose nanofiber‐based emulsion coatings with enhanced hydrophobicity and surface adhesion for preserving anthocyanins within thermally processed blueberries packed in aqueous media
Authors: Lin Chieh‐Yi , Jung Jooyeoun , Zhao Yanyun 
Published: January 2023

AbstractTo enhance hydrophobicity and surface adhesion of edible coatings onto blueberries, an emulsion system consisting of polysaccharides and oleic acid (OA) was developed and incorporated into layer‐by‐layer (LBL) cellulose nanofiber (CNF)‐based coating. The surface tension (ST) of CNF‐based emulsion coating with chitosan (CS), carboxymethyl cellulose (CMC) and OA was 34.28 mN/m, within the range of critical ST (28.41–37.52 dyne/cm) of blueberry surface after washing and copigmentation treatment by phenolic acid, which is essential to ensure good adhesion of coatings on fruit surface. CNF‐based emulsion coating demonstrated lower water sorption (9.47%) and water solubility (35.42%) and higher water contact angle (82.49 °) than CNF‐based coating without emulsion (control; 378.60%, 51.72%, and 67.37 °, respectively). CNF‐based emulsion coating also showed lower tensile strength (5.9 MPa) and elongation at break (2.55%) than control (28.17 MPa and 17.85%, respectively). CNF‐based emulsion coating was validated on thermally processed blueberries for preventing anthocyanin pigment leaching as the first layer in a LBL coating system with sodium alginate as the second layer. The CNF emulsion incorporated LBL coating system significantly preserved anthocyanin pigment in the processed blueberries compared with that of control due to increased surface adhesion and hydrophobicity and decreased mechanical damage. This study demonstrated the effectiveness of emulsion system in coatings for enhancing hydrophobicity and surface adhesion of coatings to preserve the nutritional and organoleptic qualities of thermally processed blueberries.Practical ApplicationDegradation of anthocyanins in processed fruit and fruit products has been a long‐term challenge for processed food industry. The hydrophobic and heat‐resistant coatings developed in this study can be used to preserve antioxidant anthocyanin pigments within fruit when subjected to thermal (simulated canning) process in aqueous solution, thus overcoming the barriers that the food industry has been facing. CNF plays a critical role to enhance thermal stability and adhesion of coatings onto fruit surface. The developed technology can be utilized for not only improving existing products, but also developing new and novel fruit products.
Clinical evaluation of fall risk in older adults who use lower‐limb prostheses: A scoping review
Authors: Finco M. G. , Sumien Nathalie , Moudy Sarah C. 
Published: January 2023

AbstractBackgroundNo reviews or evidence‐based clinical protocols exist to evaluate fall risk in older adults who use lower‐limb prostheses, despite falls being prevalent and costly in this population. This scoping review sought to determine assessments, defined as clinical outcome measures and gait parameters, associated with fall risk in this population to determine if a systematic review is warranted and help inform an evidence‐based clinical protocol.MethodsGoogle Scholar, PubMed, and Scopus were searched on April 19th, 2022 to include peer‐reviewed original research. Included articles reported relationships between falls and clinical outcome measures or gait parameters in older adults who use transtibial or transfemoral prostheses. Clinical outcome measures included self‐reported questionnaires and functional mobility tests. Gait parameters included spatiotemporal, kinematic, and kinetic data during walking and stair negotiation.ResultsNineteen articles were included. Clinical outcome measure scores, gait parameter data, and cutoff scores by fall status (nonfallers, single fallers, recurrent fallers) were summarized. Six articles determined clinical outcome measures that had statistically significant associations with falls, and two articles determined gait parameters that had statistically significant associations with falls.ConclusionsThe majority of articles found no clinical outcome measure or gait parameter alone was effective at identifying fall risks in this population. Future research should evaluate a combination of assessments and collect prospective fall data to move towards establishing an evidence‐based protocol to evaluate fall risk in older adults using lower‐limb prostheses.
Frailty under COVID‐19 pandemic in Japan: Changes in prevalence of frailty from 2017 to 2021
Authors: Hirose Tamaki , Sawaya Yohei , Ishizaka Masahiro , Hashimoto Naori , Kubo Akira , Urano Tomohiko 
Published: January 2023

AbstractBackgroundAfter the outbreak of the coronavirus disease 2019 (COVID‐19), “pandemic‐associated‐frailty” or profound health deterioration, in older adults has been considered a health concern. In this study, we sought to demonstrate whether pandemic‐associated‐frailty is occurring in Japan, where the population is aging, by showing the prevalence of frailty before and during the COVID‐19 outbreak, using the same method.MethodsA total of 5222 older adults in Otawara City, Tochigi Prefecture, aged 70 and 75 were surveyed annually using a complete survey, excluding those who were certified as requiring long‐term care. Frailty during 2017–2019 before the COVID‐19 outbreak and during 2020–2021 during the COVID‐19 outbreak was determined using the Kihon Checklist (KCL). Statistical analysis was performed using the χ2 test to compare annual frailty status and Kruskal–Wallis test to compare the scores.ResultsThe frailty statuses over the five‐year period showed a significant decrease in Robust and a significant increase in Pre‐frailty and Frailty (p < 0.001). Frailty increased markedly during the second year of the pandemic. Based on the category, the scores deteriorated significantly for activities of daily living (p < 0.001), physical function (p = 0.003), oral function (p < 0.001), outdoor activity (p < 0.001), and depression (p < 0.001). Moreover, there was a significant deterioration in the total score for 25 items (p < 0.001). In addition, a significant deterioration was observed in the total score of 23 items, excluding the social withdrawal affected by self‐restraint life (p < 0.001).ConclusionsThe population prevalence of frailty in older adults increased steadily from the pre‐pandemic year through the first and second years of the pandemic. Based on the 25 questions of the KCL, two aspects including visiting friends and going out less stood out. This suggests that pandemic‐associated‐frailty occurred in Japan.
PagERF81 regulates lignin biosynthesis and xylem cell differentiation in poplar
Authors: Zhao Xin‐Wei , Wang Qiao , Wang Dian , Guo Wei , Hu Meng‐Xuan , Liu Ying‐Li , Zhou Gong‐Ke , Chai Guo‐Hua , Zhao Shu‐Tang , Lu Meng‐Zhu 
Published: January 2023

ABSTRACTLignin is a major component of plant cell walls and is essential for plant growth and development. Lignin biosynthesis is controlled by a hierarchical regulatory network involving multiple transcription factors. In this study, we showed that the gene encoding an APETALA 2/ethylene‐responsive element binding factor (AP2/ERF) transcription factor, PagERF81, from poplar 84 K (Populus alba × P. glandulosa) is highly expressed in expanding secondary xylem cells. Two independent homozygous Pagerf81 mutant lines created by gene editing, produced significantly more but smaller vessel cells and longer fiber cells with more lignin in cell walls, while PagERF81 overexpression lines had less lignin, compared to non‐transgenic controls. Transcriptome and reverse transcription quantitative PCR data revealed that multiple lignin biosynthesis genes including Cinnamoyl CoA reductase 1 (PagCCR1), Cinnamyl alcohol dehydrogenase 6 (PagCAD6), and 4‐Coumarate‐CoA ligase‐like 9 (Pag4CLL9) were up‐regulated in Pagerf81 mutants, but down‐regulated in PagERF81 overexpression lines. In addition, a transient transactivation assay revealed that PagERF81 repressed the transcription of these three genes. Furthermore, yeast one hybrid and electrophoretic mobility shift assays showed that PagERF81 directly bound to a GCC sequence in the PagCCR1 promoter. No known vessel or fiber cell differentiation related genes were differentially expressed, so the smaller vessel cells and longer fiber cells observed in the Pagerf81 lines might be caused by abnormal lignin deposition in the secondary cell walls. This study provides insight into the regulation of lignin biosynthesis, and a molecular tool to engineer wood with high lignin content, which would contribute to the lignin‐related chemical industry and carbon sequestration.
Hiding in plain view: An historical perspective on the study of morality in personality psychology
Authors: McAdams Dan P. , Mayukha Ananya 
Published: January 2023

AbstractObjectiveWe aim to identify the major ideas and trends in the study of morality within personality psychology over the past 100 years.MethodOur historical review is organized into three sections, examining moral dimensions in personality from the standpoints of the person as (1) a social actor (moral traits), (2) a motivated agent (the mental infrastructure of morality), and (3) an autobiographical author (moral life stories).ResultsWithin the field of personality psychology, a great deal of research into morality has been hiding for decades in plain view. Accordingly, we trace the history of research on socialization and instrumental competence, altruism, moral traits and virtues, the dimensions of morality inherent in the authoritarian personality, personal values, moral reasoning, moral intuitions, and the life stories constructed by people who have distinguished themselves for moral excellence, as evidenced in extraordinary bravery, compassion, or generativity.ConclusionsIn a multitude of ways, human beings express and experience individual differences in their moral engagement of the world, all of which fall within the purview of personality psychology.