bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long-term Outcomes of Single and Dual En Bloc Kidney Transplants From Small Pediatric Donors: An ANZDATA Registry Study
Authors: Eastment Jacques G. , Ryan Elizabeth G. , Campbell Scott , Ray Mark , Viecelli Andrea K. , Jegatheesan Dev , Kanagarajah Vijay , Griffin Anthony , Preston John M. , Johnson David W. , Isbel Nicole 
Published: July 2023

Background.
Kidney transplants from small pediatric donors are considered marginal and often transplanted as dual grafts. This study aimed to compare long-term outcomes between recipients of single kidney transplants (SKTs) and dual en bloc kidney transplants (EBKTs) from small pediatric donors.

Methods.
Data were obtained from the Australia and New Zealand Dialysis and Transplant Registry. All adult recipients of kidney transplants from donors aged ≤5 y were identified. The primary outcome of interest was death-censored graft survival by donor type. The secondary outcomes were early graft loss, delayed graft function, serum creatinine posttransplantation, acute rejection, and patient survival.

Results.
There were 183 adult recipients of kidney transplants from donors aged ≤5 y old. Of these, 60 patients had EBKT grafts, 79 patients had SKT grafts, and 44 patients had grafts of unknown type. Compared with SKT donors, EBKT donors had lower mean age (P < 0.001) and body weight (P < 0.001). There was no significant difference in death-censored graft survival between the groups, with median survival of 23.8 y (interquartile range 21.2–25) in the EBKT cohort and 21.8 y (11.6–26.8) in the SKT cohort (hazard ratio 1.3; 95% confidence interval, 0.59-2.64; P = 0.56). EBKT grafts had lower acute rejection rates than SKT grafts (P = 0.014). There was no significant difference observed between groups with respect to early graft loss, delayed graft function, posttransplantation serum creatinine posttransplantation, or patient survival.

Conclusions.
EBKT and SKTs from small pediatric donors are associated with excellent long-term graft survival rates.
Static, dynamic and non‐weightbearing ultrasound evaluation of the digital flexor tendon sheath improves sensitivity and specificity of manica flexoria tears diagnosis in cobs and ponies
Authors: Marcatili Marco , Cantatore Federica , Hibner‐Szaltys Maria , Withers Jonathan 
Published: July 2023

SummaryBackgroundUltrasonography (US) is commonly used as a first‐line imaging modality in horses with lameness localised to the digital flexor tendon sheath (DFTS). The reported sensitivity of US for the detection of manica flexoria (MF) tears is low.ObjectivesTo report sensitivity (Se), specificity (Sp), positive predictive value (PPV) and negative predictive value (NPV) of US for diagnosing MF tears.Study designProspective observational study.MethodsSixty‐seven horses (70 limbs) with lameness localised to the DFTS were enrolled. All the horses underwent a standardised US examination of the DFTS including weightbearing (WB), nonweightbearing (NWB) and dynamic NWB US examination. The presence or absence of a MF tear was recorded. All the horses underwent tenoscopic examination as part of the treatment plan. The US diagnosis was recorded and compared with tenoscopic findings. Sensitivity, Sp, PPV and NPV were calculated.ResultsCobs and ponies were over‐represented (46/67 horses). Ultrasonographic examination correctly predicted the presence of a MF tear in 34/37 (92%) limbs (true positive). In 31/33 (94%) limbs, the MF was considered normal during US examination and this was confirmed during surgery (true negative). In two of 33 (6%) cases, US led to a false‐positive diagnosis. In three of 37 (8%) cases, US failed to identify the presence of a MF tear (false negative (FN)). In all three cases, the MF was only partially torn. The calculated sensitivity of ultrasonography for the detection of MF tears was 92%, specificity 94%, PPV 94% and NPV 91%. There was no significant difference in the ability of operators to identify MF tears.Main limitationsTwo different operators (both DECVS) performed the ultrasonographic examination. The operator performing the US examination was not blinded to the results of the lameness examination. The tenoscopic examination was performed by the same surgeon who had performed the lameness and ultrasonographic examination.ConclusionsUltrasonographic examination of the DFTS is an accurate diagnostic modality to rule in or out the presence of a MF tear. Partial MF tears that do not affect its distal border and/or its attachment onto the SDFT can be challenging to diagnose during US examination.
Prevention of atopic dermatitis in high‐risk neonates via different types of moisturizer application: A randomized, blinded, parallel, three‐group, phase II trial (PAF study)
Authors: Inuzuka Y. , Yamamoto‐Hanada K. , Kobayashi T. , Pak K. , Toyokuni K. , Ogita H. , Miyoshi T. , Ogawa K. , Sago H. , Ohya Y. 
Published: July 2023

AbstractBackgroundThe effectiveness of moisturizers in preventing infant atopic dermatitis (AD) remains unclear. We previously showed that using 2e moisturizer of commercial moisturizer (Shiseido Japan Co., Ltd.) at least once a day significantly prevented AD in infants as compared with as‐needed petroleum jelly. This trial aimed to determine the effectiveness of twice‐ or once‐daily application of Fam's Baby moisturizer (Fam's Inc.) in preventing AD compared with once‐daily 2e moisturizer.MethodsThis trial was a single‐centre, three‐parallel‐group, assessor‐blinded, superiority, individually randomized, controlled, phase II trial that was conducted from 25 August 2020 to 28 September 2021. We randomly assigned 60 newborns with at least one parent or sibling who has AD to receive Fam's Baby moisturizer twice daily (Group A) or once daily (Group B), or 2e once daily (Group C) in a 1:1:1 ratio until they were 32 weeks old. The primary outcome was the time of AD onset.ResultsAtopic dermatitis was observed in 11/20 (55%), 5/20 (25%) and 10/20 (50%), infants in Groups A, B and C, respectively. Cumulative incidence values for AD according to the Kaplan–Meier method showed that infants in Group B tended to maintain an intact skin for a longer period than those in Group C (median time, not reached [NR] vs. 212 days, log‐rank test, p = 0.064). Cox regression analysis showed that the risk of AD tended to be lower in Group B (hazard ratio with group C as control, 0.36; 95% confidential intervals: 0.12–1.06). No serious adverse events occurred in any of the enrolled infants.ConclusionFam's Baby moisturizer may better prevent AD than 2e. Further large‐scale trials should be performed to confirm the efficacy of Fam's Baby moisturizer in preventing AD in infants.
Use of frailty assessment instruments in nephrology populations: a scoping review
Authors: Kennard Alice L. , Rainsford Suzanne , Glasgow Nicholas J. , Talaulikar Girish S. 
Published: July 2023

Abstract
Background
Frailty is a clinical syndrome of accelerated aging associated with adverse outcomes. Frailty is prevalent among patients with chronic kidney disease but is infrequently assessed in clinical settings, due to lack of consensus regarding frailty definitions and diagnostic tools. This study aimed to review the practice of frailty assessment in nephrology populations and evaluate the context and timing of frailty assessment.

Methods
The search included published reports of frailty assessment in patients with chronic kidney disease, undergoing dialysis or in receipt of a kidney transplant, published between January 2000 and November 2021. Medline, CINAHL, Embase, PsychINFO, PubMed and Cochrane Library databases were examined. A total of 164 articles were included for review.

Results
We found that studies were most frequently set within developed nations. Overall, 161 studies were frailty assessments conducted as part of an observational study design, and 3 within an interventional study. Studies favoured assessment of participants with chronic kidney disease (CKD) and transplant candidates. A total of 40 different frailty metrics were used. The most frequently utilised tool was the Fried frailty phenotype. Frailty prevalence varied across populations and research settings from 2.8% among participants with CKD to 82% among patients undergoing haemodialysis. Studies of frailty in conservatively managed populations were infrequent (N = 4). We verified that frailty predicts higher rates of adverse patient outcomes. There is sufficient literature to justify future meta-analyses.

Conclusions
There is increasing recognition of frailty in nephrology populations and the value of assessment in informing prognostication and decision-making during transitions in care. The Fried frailty phenotype is the most frequently utilised assessment, reflecting the feasibility of incorporating objective measures of frailty and vulnerability into nephrology clinical assessment. Further research examining frailty in low and middle income countries as well as first nations people is required. Future work should focus on interventional strategies exploring frailty rehabilitation.
MENINGKATKAN KEMAMPUAN PEMECAHAN MASALAH MATEMATIKA SISWA SD MELALUI PENDEKATAN OPEN-ENDED
Authors: SITANGGANG ANDRI KRISTIANTO 
Published: July 2023

Penelitian ini bertujuan untuk untuk mengetahui perbedaan peningkatan kemampuan pemecahan masalah matematika yang menerapkan pendekatan open-ended dengan pembelajaran biasa pada siswa Kelas VI SD St.Thomas 4 Medan. Populasi dalam penelitian ini adalah seluruh siswa Kelas VI SD St.Thomas 4 Medan Tahun Ajaran 2009/2010. Sampel penelitian adalah seluruh siswa kelas VI, dipilih secara acak dua kelas SD St.Thomas 4 Medan. Kriteria pengujian hipotesisi adalah : Ha diterima jika , dimana diperoleh dari daftar distribusi t dengan dk = () dengan peluang dan taraf nyata = 0,05. Untuk harga thitung lainnya Ho ditolak. Hasil analisis dari data gain kelas Open-Ended dengan kelas Konvensional dengan menggunakan uji t, diperoleh harga thit = 4,32 harga ttabel = pada dk =78 dan taraf signifikansi a = 0,05 diperoleh ttabel = 1,667, ternyata thit > ttabel maka Ha diterima. Dengan demikian dapat disimpulkan bahwa terdapat perbedaan peningkatan kemampuan pemecahan masalah matematika yang diajar dengan pembelajaran Open-Ended dengan siswa yang diajar dengan pembelajaran konvensional. Kata kunci : Open-Ended, pemecahan masalah
CHRISTIAN-ANTHROPOLOGY IDEA OF EDUCATION IN THE HERITAGE OF SENIOR SLAVOPHILS
Authors: Близнецова Ю.С. 
Published: July 2023

Посредством герменевтического анализа философско-педагогических воззрений старших славянофилов сформулированы теоретикоконцептуальные положения, характеризующие сущность христианскоантропологической идеи воспитания. В контексте идеала целостной личности мыслителями дано обоснование иерархического устроения человека и примата духовного начала в нем. Целью воспитания в понимании философов является спасение человека, обретение им целостности и подлинной свободы посредством воцерковления.
By means of hermeneutic analysis of the philosophical and pedagogical views of the senior Slavophiles, theoretical and conceptual provisions that characterize the essence of the Christian anthropology idea of education have been formulated. In the context of the ideal of a holistic personality, the thinkers substantiated the hierarchical structure of a person and the primacy of the spiritual principle in him. The goal of education according to philosophers is the salvation of a person, the restoring his integrity and attaining his freedom by means of churching.
Corrosion of Electrical Submersible Pumps (ESP) In South Rumaila Oil Field
Authors: Saleh Talib Abdullah , Sahi Safaa Husain , Mohamed Layla Sideeq 
Published: July 2023

Rotating cylinder electrode (RCE) is used . in weight loss technique , the salinity is 200000 p.p.m, temperatures are (30,5060,7080Co) . the velocity of (RCE) are (500,1500,3000 r.p.m). the water cut (30% , 50%). The corrosion rate of carbon steel increase with increasing rotating cylinder velocity. In single phase flow, an increase im rotational velocity from 500 to 1500 r.p.m, the corrosion rate increase from 6.88258 mm/y to 10.11563 mm/y respectively.
In multiphase flow, an increase in (RCE) from 500 to 1500 r.p.m leads to increase in corrosion rate from 0.786153 to 0.910327 mm/y respectively. Increasing brine concentration leads to increase in corrosion rate at water cut 30%.
The impact of valvular heart disease in patients with chronic coronary syndrome
Authors: Molenaar Mitchel A. , Bouma Berto J. , Coerkamp Casper F. , Man Jelle P. , Išgum Ivana , Verouden Niels J. , Selder Jasper L. , Chamuleau Steven A. J. , Schuuring Mark J. 
Published: July 2023

BackgroundThe European Society of Cardiology 2019 Guidelines on chronic coronary syndrome (CCS) recommend echocardiographic measurement of the left ventricular function for risk stratification in all patients with CCS. Whereas CCS and valvular heart disease (VHD) share common pathophysiological pathways and risk factors, data on the impact of VHD in CCS patients are scarce.MethodsClinical data including treatment and mortality of patients diagnosed with CCS who underwent comprehensive transthoracic echocardiography (TTE) in two tertiary centers were collected. The outcome was all-cause mortality. Data were analyzed with Kaplan-Meier curves and Cox proportional hazard analysis adjusting for significant covariables and time-dependent treatment.ResultsBetween 2014 and 2021 a total of 1,984 patients with CCS (59% men) with a median age of 65 years (interquartile range [IQR] 57–73) underwent comprehensive TTE. Severe VHD was present in 44 patients and moderate VHD in 325 patients. A total of 654 patients (33%) were treated with revascularization, 39 patients (2%) received valve repair or replacement and 299 patients (15%) died during the median follow-up time of 3.5 years (IQR 1.7–5.6). Moderate or severe VHD (hazard ratio = 1.33; 95% CI 1.02–1.72) was significantly associated with mortality risk, independent of LV function and other covariables, as compared to no/mild VHD.ConclusionsVHD has a significant impact on mortality in patients with CCS additional to LV dysfunction, which emphasizes the need for a comprehensive echocardiographic assessment in these patients.
Effect of neonatal and adult sepsis on inflammation-related diseases in multiple physiological systems: a Mendelian randomization study
Authors: Li Suping , Wang Qian , Tan Xin , Wang Linghua , Gong Jin , Zhang Juan , Wang Weilin , Liu Jiangling 
Published: July 2023

BackgroundLong-term impact of sepsis on whole body systems is not well investigated. The aim of the study was to explore the potential association of neonatal/adult sepsis with several inflammation-related diseases in multiple physiological systems.MethodsInstrumental variables for neonatal and adult sepsis were collected from the public genome-wide association studies, which must satisfy the correlation, exclusivity and independence assumptions. Mendelian randomization methods (including random-effect inverse-variance weighted, MR-PRESSO, weighted median and MR-Egger) were used to determine the genetic association of neonatal/adult sepsis with asthma, allergy, rheumatoid arthritis, body mass index/obesity, type 1/type 2 diabetes and intelligence/dementia. Sensitivity analyses were conducted to assess heterogeneity and horizontal pleiotropy. The study was performed by TwoSampleMR in R software.ResultsThe inverse-variance weighted method reported that neonatal sepsis was related to the decreased level of body mass index (OR = 0.988, 95%CI = 0.980 ~ 0.997, P = 0.007), and adult sepsis was related to the decreased risk of obesity (OR = 0.785, 95%CI = 0.655 ~ 0.940, P = 0.009). These results were supported by the other Mendelian randomization methods. In addition, the study did not find any association of neonatal/adult sepsis with the other inflammation-related diseases. No heterogeneity and horizontal pleiotropy were found using sensitivity analyses.ConclusionSepsis had the potential to reduce the risk of obesity or body mass index level at a genetic level, both in neonates and in adults.
Effect of replacement therapy (CRRT) and hemodialysis (IHD) on severe acute renal failure
Authors: Zhang Xiangyuan , Yuan Yinfang 
Published: July 2023

Hyperkalemia, metabolic acidosis, and acute uremia are the main symptoms in patients with severe acute renal failure (SARF). Its clinical symptoms are obvious, and it is extremely harmful. It needs to take active and effective measures for treatment. CRRT refers to any extracorporeal blood purification treatment technique designed to replace impaired renal function for 24 h or nearly 24 h. Hemodialysis treatment is a treatment process in which the patient’s blood is discharged from the body, passes through the dialysis membrane and dialysis machine, removes excess toxins and water in the body, corrects electrolyte and acid-base disorders, and then returns the blood to the body. In order to explore the efficacy of replacement therapy and hemodialysis in the treatment of severe acute renal failure, the data samples were randomly divided into observation group and control group, who were given conventional treatment, hemodialysis and replacement therapy, respectively. Clinical data show that after replacement therapy and hemodialysis in patients with severe acute renal failure in the observation group, the levels of parathyroid hormone, renin, and quality of life were all improved, with an improvement rate of 9.47%, which has certain promotional value.
Family function and adolescent altruistic behavior: the multiple mediating effects of self-affirmation and psychological resilience
Authors: Cui Hongbo , Bi Xiaoyan , Zhou Xiaowen , Zhang Weixin , Ma Yankun 
Published: July 2023

IntroductionThe current study aimed to explore the relationship between family function and adolescent altruistic behavior, as well as the mediating effects of self-affirmation and psychological resilience in this relationship.MethodsA survey was conducted on 972 high school students in Guangdong Province using the Family APGAR, GHQSense of Adequacy, Chinese version of Connor-Davidson Resilience Scale, and Altruistic Behavior Scale.ResultsResults found that the score of psychological resilience of males was significantly higher than that of females, but the score of altruistic behavior was significantly lower than that of females. Family function had a positive predictive effect on altruistic behavior. Psychological resilience played a mediating role between family function and altruistic behavior. Self-affirmation and psychological resilience played chain mediating roles between family function and altruistic behavior.DiscussionThis study indicated that family care is crucial for the development of adolescent altruistic behavior, and that it can promote the development of altruistic behavior through the enhancement of self-affirmation and psychological resilience.
Designing Teaching Activity
Authors: Zamzami Muhammad Rizal Akbar , Zamzami Muhammad Ana 
Published: July 2023

The article discusses the idea of designing teaching approach by using cartoon videos as a tool for teaching vocabulary to young learners, specifically 4th and 5th grade elementary school students who are typically 10-11 years old. The article emphasizes that in the current modern era, a variety of media have already become a part of our daily lives, particularly for children who watch YouTube, Tiktok, and other ssocial media videos. Consequently, teaching and learning process should adapt with the advancement of technology. Designing teaching vocabulary for young learners by using cartoon videos are suitable since young learners are more open-minded, have developed concrete operational thinking, and are motivated to solve their own learning problems. This article also provides a lesson plan which can be utilized in Classroom Action Research (CAR). Overall, the article believes that using cartoon videos is an effective teaching strategy for young learners because it is engaging, enjoyable, and it helps students to learn more effectively.

Keywords: cartoon videos, teaching vocabulary, young learners
Evaluation of central and local economic policies on hawkers in the post-epidemic era and suggestions for improvement
Authors: Huang Jiahao , Li Tongyu , Chen Xiaoyin , Huang Shiyang 
Published: July 2023

In response to the economic downturn caused by the COVID-19 epidemic, the Chinese government has released a series of policies to encourage the hawker economy. The objective of the study is to provide references for the establishment and improvement of China’s hawker economic policy. In this paper, a sample of 105 hawker economy policies from 2020 to 2022 is selected, and the policy texts are analyzed and evaluated by constructing a three-dimensional analysis framework of “tool-subject-effectiveness”, using content analysis and the PMC index model. The results of the study revealed that the development of central and local policy tools is uneven; central government subjects focus on top-level design, while local government subjects focus on practice; and the policies generally show good effectiveness. Based on this, the paper put forward relevant suggestions.
Análisis de la presencia, uso y relevancia social de Facebook en las entidades locales de la provincia de Lugo
Authors: Rivera Capón Pablo , Díaz-Varela López Andrés 
Published: July 2023

Este artículo surge con el objetivo de calibrar en qué medida las pequeñas entidades locales han sabido incorporar Facebook a su actividad cotidiana, partiendo de la base de que la mayor proximidad con el ciudadano favorece su predisposición a la hora de contar con la nueva generación de tecnologías de la información y de la comunicación que la sociedad asume de manera masiva. El universo elegido —las entidades locales de la provincia de Lugo— define un marco de organizaciones públicas de dimensiones reducidas (mayoritariamente de menos de 5.000 habitantes), marcado carácter rural y edad media de la población elevada, y demuestra su apuesta por utilizar esta plataforma como una herramienta más con la que difundir información veraz de manera ágil, a pesar de su incapacidad para aprovechar todas sus potencialidades, especialmente la bidireccionalidad, porque se han refugiado en comportamientos comunicativos donde las opiniones de los ciudadanos tienen poco valor y como consecuencia han generado perfiles que carecen de la actividad e interacción necesaria para la conformación de espacios dialógicos.