bluuebunny/crossref_metadata_2025_split huggingface dataset:
Energy-based design procedure for self-centering shear wall systems
Authors: Song Ge , Xing Lili 
Published: April 2023

Abstract
Self-centering shear wall systems (SCSWSs) exhibit superior aseismic capacities with low-damage and self-centering features. However, the cumulative effect under long-period earthquakes would diminish robustness of the system and lead to increased unrecoverable damages. Thus, it should be considered in seismic designs for SCSWSs. This paper proposes an energy-based design procedure (EBDP) applicable to the Chinese code for SCSWSs. The hysteretic energy demand EH is introduced as a critical design index to account for cumulative effects, which is quantified considering both the structural features and soil types specified in the Chinese code. Meanwhile, the desired damage state is considered explicitly by assigning a performance-based damage index in the procedure. EBDP enables designers to conduct multi-level designs for SCSWSs by selecting different performance objectives under multiple seismic intensities. A design example is performed to verify the applicability and reasonability of the proposed EBDP. The performance of the designed SCSWS is evaluated and compared with a SCSWS designed by direct displacement-based design method (DDBD). Results indicate that EBDP designed structure exhibits better aseismic capacity with more controllable damage development. Structural responses are in good accordance with design performance objectives, implying that the proposed EBDP can provide reasonable design results for SCSWSs.
Turkey Adenovirus 3: ORF1 Gene Sequence Comparison Between Vaccine-Like and Field Strains
Authors: Quaglia Giulia , Francesco Antonietta Di , Catelli Elena , Mescolini Giulia , Lupini Caterina 
Published: April 2023

Abstract
Haemorrhagic enteritis is an economically significant disease reported in the majority of the countries where turkeys are raised intensively; it is caused by turkey adenovirus 3 (TAdV-3). The aim of this study was to analyse and compare the ORF1 gene 3′ region from turkey haemorrhagic enteritis virus (THEV) vaccine-like and field strains in order to develop a molecular diagnostic method to differentiate the strains from each other. Eighty samples were analysed by sequencing and phylogenetic analyses using a new set of polymerase chain reaction (PCR) primers targeting a genomic region spanning the partial ORF1, hyd and partial IVa2 gene sequences. A commercial live vaccine was also included in the analysis. The results showed that 56 of the 80 sequences obtained in this study showed ³99.8% nucleotide identity with the homologous vaccine strain sequence. Three non-synonymous mutations – ntA1274G (aaI425V), ntA1420C (aaQ473H) and ntG1485A (aaR495Q) – were detected in the THEV field strains but not in the vaccine strain. Phylogenetic analysis confirmed the clustering of the field and vaccine-like strains in different phylogenetic branches. In conclusion, the method employed in this study could be a useful tool towards making a correct diagnosis. The data could contribute to the knowledge of field distribution of THEV strains and increase the limited existing information available on native isolates around the world.
Assessment of mitral valve geometry in nonvalvular atrial fibrillation patients with or without ventricular dysfunction: insights from high volume rate three- dimensional transesophageal echocardiography
Authors: Bai Wenjuan , Chen Yin , Zhong Yue , Deng Ling , Li Dayan , Zhu Wei , Rao Li 
Published: April 2023

Abstract
Aims Meticulous understanding of the mechanisms underpinning mitral regurgitation in atrial fibrillation (AF) patients is crucial to optimize therapeutic strategies. The morphologic characteristics of mitral valves in atrial functional mitral regurgitation (FMR) patients with and without left ventricular (LV) dysfunction were evaluated by high volume rate (HVR) three-dimensional transesophageal echocardiography (3D-TEE).Methods and results Of 265 AF patients who underwent 3D-TEE, 68 were retrospectively selected, including 36 patients with AF, FMR, and preserved LV function (AFMR group) and 32 patients with AF, FMR, and LV dysfunction (VFMR group). In addition, 36 fever patients without heart disease were included in the control group. The left atrium (LA) was enlarged in the AFMR and VFMR groups compared with the control group. The mitral annulus (MA) in the AFMR group was enlarged and flattened compared with the control group and was smaller than in the VFMR group. The annulus area fraction was significantly diminished in the AFMR and VFMR groups, indicative of reduced MA contractility. The posterior mitral leaflet (PML) angle was smallest in the AFMR group and largest in the control group, whereas the distal anterior mitral leaflet angle did not significantly differ among the three groups.Conclusion HVR 3D-TEE improves the 3D temporal resolution greatly. LA remodeling causes expansion of the MA and reduced MA contractility, disruption of the annular saddle shape, and atriogenic PML tethering. Finally, atrial FMR occurs. Comparison of atrial FMR patients with and without LV dysfunction indicates that atriogenic PML tethering is an important factor that aggravates FMR.
Titration of oncogenic RAS alters senescent state and influences tumour initiation
Authors: Narita Masashi , Chan Adelyne , Zhu Haoran , Narita Masako , Cassidy Liam , Young Andrew , Bermejo-Rodriguez Camino , Janowska Aleksandra , oshimori Naoki , Zender Lars , Aitken Sarah , Hoare Matthew 
Published: April 2023

Abstract

Oncogenic RAS-induced senescence (OIS) is an autonomous tumour suppressor mechanism associated with pre-malignancy1-3. Achieving this phenotype typically requires a high level of oncogenic stress, yet the phenotype provoked by lower oncogenic dosage remains unclear. Here we develop oncogenic RAS-dose escalation models in vitro and in vivo, revealing a RAS-dose-driven non-linear continuum of downstream phenotypes. In a hepatocyte OIS model in vivo, where ectopic expression of NRASG12V fails to induce tumours in part due to OIS-driven immune clearance4. scRNA-seq analyses reveal distinct hepatocyte clusters with typical OIS or progenitor-like features, corresponding to high- and intermediate-NRASG12V levels, respectively. Remarkably, when titered down, NRASG12V-expressing hepatocytes become immune-resistant, and develop tumours. Time-series monitoring at single-cell resolution identifies two distinct tumour types: early-onset aggressive undifferentiated and late-onset differentiated hepatocellular carcinoma (HCC). The molecular signature of each murine tumour type is associated with different progenitor features and enriched in distinct human HCC subclasses. Our results define the oncogenic dosage-driven OIS spectrum, reconciling the senescence and tumour initiation phenotypes in early tumorigenesis.
Status, associated factors, and reasons for bypassing the childbirth center among postpartum women in the Dire Dawa Administration, Ethiopia: A Mixed Study
Authors: Mohammed Aminu , Mosa Hassen , Hailu Mickiale , Getnet Tewodros , Manaye Yibekal 
Published: April 2023

Abstract
Background Childbirth in nearby health facilities is an important strategy to reduce complications for mothers and newborns, including death. Bypassing nearby birthing health facilities is common in developing countries. However, there is a lack of data in the study area on the extent and reasons for bypassing. Therefore, this study was aimed at assessing these gaps.Methods A facility-based mixed study was conducted at the Dire Dawa administration, Ethiopia, from December 1–30, 2022. Simple random (quantitative) and purposive (qualitative) sampling techniques were used. Data were collected through interviews using structured (quantitative) and semi-structured (qualitative) questionnaires. Quantitative data were entered and cleaned by Epi DATA (Version 3.1) and analyzed using SPSS (Version 22). A P-value of 0.05 or less at multivariate with 95% confidence intervals was considered statistically significant. Qualitative data were thematically analyzed.Results 635 participants (quantitative) and twelve for the qualitative analysis were included. The overall bypass was 30.9%. Higher age group (AOR = 2.34, 95% CI: 1.43–3.82), rural residence (AOR = 1.89, 95% CI: 1.11–3.22), no formal education (AOR = 2.26, 95% CI: 1.23–4.16), obstetric care needs during antenatal care (AOR = 2.37, 95% CI: 1.33–4.22), and health professionals’ behavior (AOR = 3.10, 95% CI: 1.99–4.78) were associated with a higher likelihood of bypassing.Conclusion Bypassing childbirth health facilities was moderate. Perception, health professionals, and facility-related factors were the main identified themes in the qualitative results. Stakeholders recommended improving obstetrics services and researchers conducting additional research.
Fixed points of single and multivalued mappings in metric spaces with applications
Authors: Pant Rajendra , Khantwal Deepak 
Published: April 2023

Abstract
We point out that certain facts presents in Bisht [Comment on: A new fixed point theorem in the fractal space, Indag. Math. (N.S.) 29 (2018)] were incorrect. We also present new existence results for single and multivalued mappings in metric spaces on very general settings. Some illustrative examples are presented to validate our theorems. Finally, we discuss an application to the Volterra-type integral inclusions.
2020 Mathematics Subject Classification. Primary 47H10; Secondary 54H25.
How to stabilize the output of a time delay distributed bilinear system and application to regional stabilization
Authors: Zerrik E. , Akoubi A. , Aadi A. Ait 
Published: April 2023

Abstract
The current study focuses on the output stabilization of infinite dimensional bilinear system with time delay. We demonstrate weak stabilization under weak observability conditions, while exponential and strong stabilization can be achieved under the exact observability condition. Applications to regional stabilization through examples are given and illustrative simulations are included to affirm the accuracy of the theoretical results.
M.S.C: 93D15
Two-dimensional simulation of Argon dielectric barrier discharge (DBD) in plasma actuator structure with COMSOL Multiphysics
Authors: Mehrabifard Ramin 
Published: April 2023

Abstract
Dielectric barrier discharge (DBD) plasma is used for various applications. DBD is also one of the most efficient and low-cost methods for active fluid flow control. In this study, a detailed physical model of DBD in atmospheric pressure at 1kV DC voltage is developed with COMSOL Multiphysics software. Argon gas is also used as a background gas and electrodes are assumed to be copper. Plasma parameters such as electron and ion density, electric field, potential, and temperature for different distances of electrodes (1.0mm, 0.9mm, 0.8mm) have been investigated. Moreover, the effect of dielectric type (Quartz, Silica Glass, Mica) on these key parameters is investigated. The results of the simulation show that the longitudinal distance of the buried electrodes to the exposed electrodes has a direct influence on parameters such as electron temperature, and electron and ion density which are the main factors of fluid flow control. These parameters have the maximum value when mica is used as a dielectric and the lowest value when silica glass is utilized.
Awake Craniotomy During Pregnancy: A Systematic Review of The Published Literature
Authors: Mofatteh Mohammad , Mashayekhi Mohammad Sadegh , Arfaie Saman , Wei Hongquan , Kazerouni Arshia , Skandalakis Georgios , Pour-Rashidi Ahmad , Baiad Abed , Elkaim Lior , Lam Jack , Palmisciano Paolo , Su Xiumei , Liao Xuxing , Backman Steven , Das Sunit , Ashkan Keyoumars , Cohen-Gadol Aaron 
Published: April 2023

Abstract
Purpose Neurosurgical pathologies in pregnancy pose significant complications for the patient and fetus, and physiological stressors during anesthesia and surgery may lead to maternal and fetal complications. Awake craniotomy (AC) can preserve neurological functions while reducing exposure to anesthetic medications. We reviewed the literature investigating AC during pregnancy.Methods PubMed, Scopus, and Web of Science databases were searched from the inception to February 7th, 2023, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline. Studies in English investigating AC in pregnant patients were included in the final analysis.Results Nine studies composed of nine pregnant patients and ten fetuses (one twin-gestating patient) were included. Glioma was the most common pathology reported in six (66.7%) patients. The frontal lobe was the most involved region (4 cases, 44.4%), followed by the frontoparietal region (2 cases, 22.2%). The awake-awake-awake approach was the most common protocol in seven (77.8%) studies. The shortest operation time was two hours, whereas the longest one was eight hours and 29 minutes. The mean gestational age at diagnosis was 13.6 ± 6.5 (2–22) and 19.6 ± 6.9 (9–30) weeks at craniatomy. Seven (77.8%) studies employed intraoperative fetal heart rate monitoring. None of the AC procedures was converted to general anesthesia. Ten healthy babies were delivered from patients who underwent AC.Conclusions In experienced hands, AC for resection of cranial lesions in pregnant patients is safe and feasible and does not alter the pregnancy outcome.
Decoding Range Variability in Electric Vehicles: Unravelling the Influence of Cell-to-Cell Parameter Variation and Pack Configuration
Authors: Singh Sourabh , Mandal Sarbani , Mulpuri Sai Krishna , Sah Bikash , Kumar Praveen 
Published: April 2023

Abstract
Electric vehicles (EVs) are rapidly growing in popularity, but range variability has become an important research area with significant implications for EV performance, usability, and overall market adoption. This study aims to unravel the complexities of range variability by examining the contributing factors and offering innovative strategies to mitigate these differences during pack design. Through a detailed analysis of cell parameter deviation, cell connections, battery configuration, battery pack size, and driving behavior, the research illuminates their impact on extractable energy and driving range. The study employed a comprehensive approach and conducted systematic simulation-based experimentation to identify the optimal battery pack configuration based on maximum extractable energy, minimal variability and maximum range. The results reveal insights into the relationship between discharge rate and battery pack performance, and the impact of cell parameter variations on pack energy output. This research advances the understanding of EV performance optimisation, reduces pack-to-pack variability, and extends battery pack lifespan.
An upper bound for the Erd\H{o}s unit distance problem in the plane
Authors: Agama Theophilus 
Published: April 2023

Abstract
In this paper, using the method of compression, we prove a stronger upper bound for the Erd\H{o}s unit distance problem in the plane by showing that\begin{align}\# \bigg\{||\vec{x_j}-\vec{x_t}||:\vec{x}_t, \vec{x_j}\in \mathbb{E}\subset \mathbb{R}^2,~||\vec{x_j}-\vec{x_t}||=1,~1\leq t,j \leq n\bigg\}\ll_2 n^{1+o(1)}.\nonumber \end{align}
2000 Mathematics Subject Classification. Primary 54C40, 14E20; Secondary 46E25, 20C20.
Design of hydrodynamic cavitation-based advanced oxidation process for degradation of recalcitrant micropollutants originating from tertiary effluent streams: a case study with norfloxacin
Authors: Mishra Birupakshya , Thaker Abhishek , Mukherjee Anupam , Mullick Aditi , Roy Subhankar , Moulik Siddhartha 
Published: April 2023

Abstract
Treatment of micropollutants even after tertiary treatment and developing cost-effective, sustainable and energy-efficient technology for the same still remains an active area of research. The present study reports the feasibility and efficacy of hydrodynamic cavitation (HC)-based advanced oxidation process (AOP) for the degradation of norfloxacin. Experiments using HC were carried out in a sequential manner starting with the optimization of the cavitating device (orifice plate) using computational fluid dynamics (CFD) followed by optimizing the operational parameters such as pH, inlet pressure and initial concentration. An experimental study revealed that under optimized conditions of pH – 2, inlet pressure – 6 bar and initial conc – 250 μg/L, NRF degradation of 22.26% was obtained using HC in an experimental run of 60 min. For further improvement of the HC process, experiments were carried out by integrating with H2O2, O3 and Fenton's reagent. Under the optimized conditions, integrating with H2O2, O3 and Fenton's reagent enhanced the extent of NRF degradation. The energetics of the process was further evaluated to understand the techno-economic viability. The study revealed that HC + H2O2 consumed less energy of 8.01 kWh/m3 at the economics of Rs. 82.53/m3. Thus, HC combined with oxidizing agents can be a novel technique in the genre of AOP for the degradation of micropollutants.
Respecting local knowledge keepers through cellphilms featuring local water bodies: towards decolonizing water management
Authors: Van Borek S. , Abrams A. L. 
Published: April 2023

AbstractThis paper outlines arts-based methods aimed at exploring how storytelling with local knowledge keepers (KKs) through cellphilms featuring local waterways might contribute to decolonizing water management by uncovering different values of and relationships with water. We define ‘knowledge keepers’ as people who have an existing relationship with a particular water body and whose knowledge and expertise with respect to the water body emerge from lived experience and not academic scholarship or technical training. We provide insights into and analyse a graduate curriculum enacted in South Africa, where students, through encounters with local KKs and water bodies, made cellphilms presenting their own water narratives and screened these for the public. Cellphilms, as participatory visual methods in research and teaching, are used to explore learning experiences for students and KKs, and the resulting cellphilms become places of knowledge transfer. We outline our theoretical and methodological approaches as they relate to our goals of decolonizing expertise in higher education learning and addressing multiple types of water-related values.
HÁBITOS SALUDABLES Y FACTORES DE RIESGO EN ADOLESCENTES DE UN CENTRO PÚBLICO DE EDUCACIÓN MEDIA (Barrio de contexto crítico)
Authors: Delgado de Purtscher Teresa , Fernández Álvaro , Agazzi Beatriz , Murillo Nelly , Pereyra Isabel , Lestido Valentina 
Published: April 2023

Este estudio tiene como objetivo conocer hábitos vinculados a la Salud en adolescentes que asisten a un centro público de educación media de un barrio de contexto crítico de la ciudad de Montevideo. La población de estudio está conformada por todos los adolescentes que concurren a ese centro de educación media. El cálculo de la muestra se realizó en base a las variables de estudio (171 estudiantes). El diseño es de carácter exploratorio, descriptivo y transversal con unenfoque cuantitativo. La identificación de los riesgos para la Salud a que están sometidos estos adolescentes se centran en la actividad física, la Salud sexual y reproductiva, la Salud bucal, controles de Salud y consumo de medicamentos. Losresultados muestran datos relevantes que pueden abrirnos el camino para enfocar una atención eficaz y eficiente en bien de nuestra población joven. Como conclusiones afirmamos que es necesario buscar otras estrategias para atender a jóvenes de sectores vulnerables quienes serán los hombres y mujeres del futuro y que se encuentran con carencias en aspectos de la promoción y protección de su salud.
Avaliação da satisfação de mães em relação aos serviços públicos de saúde de Montes Claros (MG)
Authors: Nascimento Aline Lopes , Veloso Fabrícia Guimarães , Lopes Wanessa Casteluber , Pinho Lucineia de 
Published: April 2023

Este artigo pretendeu avaliar a satisfação das mães em relação aos serviços públicos de saúde de Montes Claros (MG). Para isso, realizou-se estudo transversal de base populacional, composto por amostra representativa de crianças menores de 24 meses da cidade de Montes Claros (MG), a partir de questionário descritivo, aplicado às mães dessas crianças. A análise dos dados ocorreu por meio de estatística descritiva, concluindo-se que, em relação à última consulta realizada, 70% das mães ficaram satisfeitas quanto ao tempo de espera, ao serviço de informação, à qualidade do serviço e à estrutura da unidade. Apesar de 40,1% terem relatado que tiveram consultas marcadas duas vezes ou mais no ano, consideraram o atendimento favorável. Portanto, a satisfação das mães quanto ao serviço de saúde, ao atendimento, ao acesso à atenção primária e à estrutura da unidade influenciam positivamente no tratamento da criança.
Análise de dados fora do padrão sobre a água de abastecimento da região metropolitana de Salvador
Authors: Rios Israel Henrique Ribeiro 
Published: April 2023

Os sistemas de informação do Ministério da Saúde são importantes ferramentas de planejamento das ações de saúde no território brasileiro. O Sistema de Informação de Vigilância da Qualidade da Água para Consumo Humano (Sisagua) oferece para toda a população dados sobre a situação do abastecimento de água para consumo humano, juntamente com eventuais problemas de qualidade que possam existir. É imprescindível para os gestores da área da saúde entender os maiores problemas de cada prestador de serviço de abastecimento a fim de oferecer água de boa qualidade para todas as pessoas, pois, uma vez que se trata de um bem público, todos têm direito à água de qualidade independentemente de sua condição social. Este trabalho averiguou os dados sobre a qualidade da água do estado da Bahia no período de janeiro de 2014 a março de 2022, com o objetivo de observar qual parâmetro de qualidade é responsável pela contaminações do recurso hídrico a ser consumido pelas pessoas, tornando-o fora de padrão conforme a Portaria nº 888/2021 do Ministério da Saúde. Através de gráficos de pizza gerados pelo Excel, foram averiguados os parâmetros que mais levaram a inconformidades. Foram observados, em porcentagem, os municípios que frequentemente ultrapassaram o padrão de potabilidade dentro da região. Dentro da região metropolitana de Salvador, o parâmetro cloro residual livre se destacou, seguido de cor e coliformes totais. A oferta de água doce limpa para a população é um dos pilares da saúde pública, sendo importante a constante evolução dos sistemas de abastecimento.