bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optical monitoring of hemodialysis using noninvasive measurement of uric acid in the dialysate
Authors: Żyłka Wojciech , Tęcza Krystyna , Szemela Krzysztof , Prach Piotr , Żyłka Marta , Jakubczyk Dorota , Błądziński Maciej , Gala-Błądzińska Agnieszka , Jakubczyk Paweł 
Published: August 2023

AbstractThe aim of this study was to present a methodology for predicting changes in uric acid concentrations in the blood of chronically hemodialyzed patients based on an optical measurement of the intensity of selected wavelengths in the dialysate. Blood samples were taken from the arterial line every 30 min throughout the hemodialysis period, to measure uric acid levels. Simultaneously, optical measurements were made on dialysate flowing from the dialyzer. Uric acid concentration can be measured either directly from the blood or from dialyzer outflow with acceptable error. In addition, both methods reveal any increased dynamics in uric acid concentration in the initial phase of hemodialysis. The wavelength of the light was adjusted for optimal uric acid particle detection. Comparing the uric acid concentration measured in the blood of patients with the intensity of wave absorption in the dialysate, the functional relationship between the uric acid concentration levels was determined. Using the optical method for measuring uric acid concentration in the dialysate, the concentration of uric acid in the blood during hemodialysis can be non-invasively and accurately estimated. This method can be used to assess the adequacy of hemodialysis by computer acquisition of uric acid concentrations determined in on-line dialysate.
Multispectral sensor fusion in SmartWatch for in situ continuous monitoring of human skin hydration and body sweat loss
Authors: Volkova Elena , Perchik Alexey , Pavlov Konstantin , Nikolaev Evgenii , Ayuev Alexey , Park Jaehyuck , Chang Namseok , Lee Wonseok , Kim Justin Younghyun , Doronin Alexander , Vilenskii Maksim 
Published: August 2023

AbstractPost-pandemic health operations have become a near-term reality, discussions around wearables are on the rise. How do wearable health solutions effectively deploy and use this opportunity to fill the gap between wellness and healthcare? In this paper, we will talk about wearable healthcare diagnosis, with a particular focus on monitoring skin hydration using optical multi-wavelength sensor fusion. Continuous monitoring of human skin hydration is a task of paramount importance for maintaining water loss dynamics for fitness lovers as well as for skin beauty, integrity and the health of the entire body. Preserving the appropriate levels of hydration ensures consistency of weight, positively affects psychological state, and proven to result in a decrease in blood pressure as well as the levels of “bad” cholesterol while slowing down the aging processes. Traditional methods for determining the state of water content in the skin do not allow continuous and non-invasive monitoring, which is required for variety of consumer, clinical and cosmetic applications. We present novel sensing technology and a pipeline for capturing, modeling and analysis of the skin hydration phenomena and associated changes therein. By expanding sensing capabilities built into the SmartWatch sensor and combining them with advanced modeling and Machine Learning (ML) algorithms, we identified several important characteristics of photoplethysmography (PPG) signal and spectral sensitivity corresponding to dynamics of skin water content. In a hardware aspect, we newly propose the expansion of SmartWatch capabilities with InfraRed light sources equipped with wavelengths of 970 nm and 1450 nm. Evaluation of the accuracy and characteristics of PPG sensors has been performed with biomedical optics-based simulation framework using Monte Carlo simulations. We performed rigorous validation of the developed technology using experimental and clinical studies. The developed pipeline serves as a tool in the ongoing studies of the next generation of optical sensing technology.
Strengthening the mechanical characteristics and cathodic delamination resistance of fiber-reinforced polymer through chemical surface modification of glass fibers
Authors: Shariatmadar M. , Feizollahi S. , Gholamhosseini P. , Abdorrezaee Z. , Ghorbanzadeh S. , Hosseini F. S. , Shahraki F. Azad , Mahdavian M. 
Published: August 2023

AbstractThis work aims to scrutinize the effect of the silanization of glass fibers (GF) on the mechanical properties and cathodic disbonding resistance of an epoxy composite coating. Successful silanization was approved based on different characterization techniques, including Fourier transform infrared spectra, field emission-scanning electron microscopy (FE-SEM), energy-dispersive X-ray spectroscopy, and thermogravimetric analysis. Tensile strength measurement exhibited a significant effect of silanization on the mechanical performance of the fiber-reinforced polymer (FRP). FE-SEM cross-sectional images illustrated improved interfacial bonding between the epoxy matrix and GF upon silanization. Pull-off measurements revealed improved wet adhesion strength of the FRP to the mild steel surface after exposure to the salt spray chamber when the GF were silanized. In addition, silanization revealed enhanced resistance to cathodic delamination (CD). Electrochemical impedance spectroscopy and electrochemical noise assessments proved silanization's significant influence on the FRP's CD resistance.
Simple standing test without furosemide is useful in the diagnosis of primary aldosteronism
Authors: Iwamoto Yuichiro , Kimura Tomohiko , Ohnishi Mana , Kusano Takashi , Takenouchi Haruka , Iwamoto Hideyuki , Sanada Junpei , Fushimi Yoshiro , Katakura Yukino , Tatsumi Fuminori , Shimoda Masashi , Nakanishi Shuhei , Kaku Kohei , Mune Tomoatsu , Kaneto Hideaki 
Published: August 2023

AbstractPrimary aldosteronism (PA) is a well-known cause of secondary hypertension. We have long performed the simple standing test in patients with PA. On the other hand, there are few reports on the usefulness of the simple standing test in PA. This study is a single-center, retrospective, observational study. A total of 173 patients with hypertension or adrenal tumor admitted to Kawasaki Medical School were included. Eighty patients who met the exclusion criteria were excluded, and 31 patients without PA (non-PA), 26 patients with unilateral PA, and 36 patients with bilateral PA were included in the study. The simple standing test was performed after 120 min of standing or sitting followed, and the aldosterone/renin ratio (ARR) and percentage of increase plasma aldosterone concentration (%increase of PAC) was calculated. The mean ARR in the simple standing test in unilateral PA (1143 (528–2200)) and bilateral PA subjects (521 (374–765)) were significantly higher compared to non-PA subjects (152 (102–240)) (p < 0.0001, p = 0.0013, respectively). The percentage increase of PAC after standing loading was significantly lower in unilateral PA subjects (110 (96–140)) compared to non-PA subjects (187 (155–244)) (p = 0.0003), with no difference between non-PA and bilateral PA subjects (p = 0.99). The cutoff value of the ARR in the simple standing test for diagnosis of PA in this study was 364 (AUC = 0.948, sensitivity = 83.8%, specificity = 93.5%, false positive rate = 3.7%, false negative rate = 25.6%, p < 0.001), which was not inferior to the diagnostic performance of the captopril loading test. The diagnostic performance of the simple standing test for PA was not inferior to that of the captopril loading test. The percentage increase of PAC in unilateral PA subjects was significantly lower compared to bilateral PA subjects. These results demonstrate the usefulness of the simple standing test, which can be performed simultaneously with general screening tests of PA.
The growth and developmental of the myodural bridge and its associated structures in the human fetus
Authors: Song Yang , Lai Hua-Xun , Song Ting-Wei , Gong Jin , Liu Bo , Chi Yan-Yan , Yue Chen , Zhang Jing , Sun Shi-Zhu , Zhang Cheng-Hong , Tang Wei , Fan Ning , Yu Wei-Hua , Wang Yi-Fei , Hack Gary D. , Yu Sheng-Bo , Zhang Jian-Fei , Sui Hong-Jin 
Published: August 2023

AbstractMyodural bridge (MDB) is a dense connective tissue between suboccipital muscle and dura mater. However, there are few reports on the development and maturation of the human MDB. This study aims to explore the developmental relationship between suboccipital muscle and MDB. 30 head and neck specimens from human fetuses (F) ranging from the 12th to 41st week (W) were made into histological sections. The F12W sections showed evidence that the dura mater dominated by fibroblasts, attached to the posterior atlanto-axial membrane (PAAM) which completely sealed the atlanto-axial space. In the F13W stage, myofibrils of the suboccipital muscle fibers increased significantly in number. At the F14W stage, a gap was observed at the caudal end of the PAAM. Numerous myodural bridge-like structures were observed blending into the dura mater through the gap. At the F19W stage, muscle cells mature. Starting at the F21W stage, the MDB were observed as fibroblasts that cross the atlanto-axial interspace and attach to the dura mater. Therefore, the traction generated by the suboccipital muscles seems to promote the maturity of MDB. This study will provide new morphological knowledge to support future research on the function of the human MDB and regulating the development mechanism of MDB.
Reducing Carbon Footprint with Real-Time Transport Planning and Big Data Analytics
Authors: Zrigui Ismail , Khoulji Samira , Larbi Kerkeb Mohamed , Ennassiri Ayoub , Bourekkadi Salmane 
Published: August 2023

The growing concern about the impact of transportation on the environment has led to increased interest in developing more sustainable transportation systems. This paper presents a new approach to reduce carbon footprint by using real-time transport planning and big data analytics. The objective is to optimize transport operations, thereby reducing fuel consumption and greenhouse gas emissions.
The current state of knowledge and the question posed in this paper is how to achieve sustainable transportation systems. To address this issue, the methodology used involves collecting data from traffic sensors and other sources to create real-time traffic models that can be used for optimal transport planning. Statistical modeling and machine learning techniques are applied to improve the accuracy of traffic predictions and optimize the routing of vehicles.
The main results of this study demonstrate that the proposed approach is effective in reducing fuel consumption and greenhouse gas emissions. By analyzing real-time traffic data and optimizing transport operations, it is possible to reduce carbon footprint significantly. The benefits of this approach extend beyond the environment, as it can also lead to cost savings for transportation companies and improve traffic flow for road users.
The consequences of this research are significant, as it offers a new solution for reducing the environmental impact of transportation. The proposed approach can be applied to a variety of transportation modes, including cars, trucks, and public transportation, and has the potential to be implemented in various cities and regions. By reducing carbon footprint, this approach can contribute to achieving global targets for reducing greenhouse gas emissions, as well as improve the overall sustainability of transportation systems.
Remediation of soil contaminated with Mn, Cu and Zn around the Mbembele mine in Gabon: Phytoremediation approach (Vetiveria zizanioides and Phacelurus gabonensis)
Authors: Bekoung Assoumou Rudy , Ondo Zue Abaga Norbert , Tayebi Mohamed 
Published: August 2023

The ability of Vetiveria zizanioides and Phacelurus gabonensis to accumulate copper (Cu), zinc (Zn) and manganese (Mn) in the aerial parts and to mobilise them in the roots is applied. This investigation is based on the in situ observation of these plants, their biomass and the evaluation of the translocation capacity of each metal from roots to aerial parts.
A proliferation of both plants in culture was observed for three months, then harvested and analysed. Significant metal contents, on 250 mg of samples taken, are observed in the aerial parts of Phacelurus gabonensis (2028 ppm of Cu, 9 ppm of Zn and 7456 ppm of Mn) whereas (3854 ppm Cu, 268 ppm Zn 43005 ppm of Mn) in the roots. Vetiveria zizanioides records in the aerial parts 83 ppm Cu, 31 ppm Zn and 8761 ppm, Mn while in the roots there are 83 pm Cu, 1974 ppm Zn and 11930 ppm Mn. The ability to transfer these metals from the roots to the aerial parts is greater in Vetiveria zizanioides than in Phacelurus gabonensis despite the high metal concentrations in the aerial parts in Phacelurus gabonensis.The high concentrations of metals purified by Phacelurus gabonensis and Vetiveria zizanioides place them among the top ranks of phytoremediation.
Virale Bindehautentzündungen: Befunde, Therapie und
Prophylaxe
Authors: Kowanz Dominik H. , Rokohl Alexander C. , Heindl Ludwig M. 
Published: August 2023

ZusammenfassungBesonders in den Winter- und Herbstmonaten füllen sie Augenarztpraxen und
Ambulanzen von Augenkliniken: Patienten mit stark geröteten, tränenden Augen,
die oftmals auch zusätzliche Allgemeinsymptome zu beklagen haben. Doch nicht
jede Bindehautentzündung wird durch respiratorische Erreger mit typischer,
saisonaler epidemiologischer Dynamik verursacht, bei bestimmten Erregern
manifestiert sich in erster Linie ein charakteristischer Hautbefund.
Regulatorische B-Zellen – immunpathologisches und
prognostisches Potenzial beim Menschen
Authors: Veh Johanna , Ludwig Carolin , Schrezenmeier Hubert , Jahrsdörfer Bernd 
Published: August 2023

ZusammenfassungRegulatorische B-Zellen (Bregs) stellen eine heterogene Gruppe von B-Zellen dar,
welche in der Lage sind, inflammatorische Immunantworten zu
unterdrücken. Bregs tragen damit zur Aufrechterhaltung von Toleranz und
zur Immunhomöostase bei, indem sie laufende Immunreaktionen
räumlich und zeitlich begrenzen. Die herausragende Rolle von Bregs bei
der Eindämmung pathologisch überschießender
Entzündungsreaktionen, mit der sowohl Allergien, Autoimmunerkrankungen
und Transplantatabstoßungen, aber auch Infektionen, Neoplasien und
Stoffwechselerkrankungen einhergehen können, wurde in einer Vielzahl von
Tiermodellen nachgewiesen. Die ersten Studien zu Bregs identifizierten IL-10 als
funktionelles Schlüsselmolekül, weshalb die murine
IL-10-produzierende B10-Zelle noch immer als Prototyp für Bregs gilt und
IL-10 bei der Suche nach humanen Äquivalenten für Bregs lange im
Vordergrund stand. In den letzten 2 Jahrzehnten wurde jedoch eine ganze Reihe
weiterer Moleküle entdeckt, die – teilweise auch
ausschließlich in humanen Bregs – zu ihrer immunsuppressiven
Funktion beitragen können. Zu diesem erweiterten Arsenal gehören
zum einen weitere entzündungshemmende Zytokine wie IL-35 und
TGF-β, aber auch Enzyme wie Granzym B, CD39/CD73 und IDO, sowie
Zelloberflächenproteine wie CD1d, PD-L1 und CD25. Ziel des vorliegenden
Übersichtsartikels soll es sein, die mutmaßliche Rolle von Bregs
insbesondere bei unterschiedlichen Humanpathologien zu beleuchten und dabei ihre
potenzielle therapeutische und prognostische Relevanz hervorzuheben.
An Approach to Nodal T- and NK-Cell Lymphomas—A Systemic Review
Authors: Parkhi Mayur , Bal Amanjit 
Published: August 2023

AbstractT-cell lymphomas are rare neoplasms that have complex pathology. The multiparameter approach has been recommended by World Health Organization (WHO) for the classification of T-cell lymphomas taking into account morphology, immunophenotype, genetics, and clinical features. This also includes division established on the possible cell-of-origin (COO) from T regulatory or T-follicular helper (TFH) cells. The recent WHO-HAEM5 has classified entities as precursor T-lymphoblastic neoplasms, mature T-cell neoplasms, Epstein-Barr virus (EBV)-related T- and NK/T-cell lymphomas, and tumor-like lesions with T-cells predominance. Distinct entities have been recognized within the anaplastic large cell lymphoma (ALCL) family founded on the status of anaplastic lymphoma kinase (ALK) gene rearrangement: ALK-positive and molecularly heterogeneous ALK-negative. The family of lymphomas arising from TFH cells consists of three distinct nodal TFH cell lymphoma entities: angioimmunoblastic-type, follicular-type, and not otherwise specified. These three entities show significant clinical and immunophenotypic overlap. The cases that do not qualify for ALCL or nodal TFH cell lymphomas are labelled as peripheral T-cell lymphomas-not otherwise specified after ruling out nodal EBV-positive T- and NK- cell lymphoma. The new category termed tumor-like lesions with T cell predominance has a high chance to be misdiagnosed as lymphoma. This category includes entities such as Kikuchi-Fujimoto disease, indolent T-lymphoblastic proliferation, and autoimmune lymphoproliferative syndrome. For pathologists, diagnosing nodal T-cell lymphomas may be thought-provoking due to their broad histopathologic spectrum that mimics reactive as well as other neoplastic processes. This review provides a comprehensive diagnostic criterion of the most commonly encountered nodal T-cell and NK cell lymphomas in day-to-day training and an algorithmic approach.
Word order evolves at similar rates in main and subordinate clauses
Authors: Jing Yingqi , Widmer Paul , Bickel Balthasar 
Published: August 2023

Abstract
In syntactic change, it remains an open issue whether word orders are more conservative or innovative in subordinate clauses compared with main clauses. Using 47 dependency-annotated corpora and Bayesian phylogenetic inference, we explore the evolution of S/V, V/O, and S/O orders across main and subordinate clauses in Indo-European. Our results reveal similar rates of change across clause types, with no evidence for any inherent conservatism of subordinate or main clauses. Our models also support evolutionary biases towards SV, VO, and SO orders, consistent with theories of dependency length minimization that favor verb-medial orders and with theories of a subject preference that favor SO orders. Finally, our results show that while the word order in the proto-language cannot be estimated with any reasonable degree of certainty, the early history of the family was dominated by a moderate preference for SVO orders, with substantial uncertainty between VO and OV orders in both main and subordinate clauses.
How reliable are light traps in estimating biting rates of adult Anopheles gambiae s.l. (Diptera: Culicidae) in the presence of treated bed nets?
Authors: Magbity E.B. , Lines J.D. , Marbiah M.T. , David K. , Peterson E. 
Published: August 2023

AbstractThe sampling efficiency of light trap catches relative to human bait catches in estimating biting rates of the mosquito Anopheles gambiae Giles was investigated in two types of community in southern Sierra Leone: (i) where most of the inhabitants slept under treated bed nets; and (ii) where most of the inhabitants slept without bed nets. The number of female A. gambiae mosquitoes caught in these communities by light trap was strongly correlated (r ≥ 0.72) with those from corresponding human biting catches performed either on the same or adjacent nights. It was found that the relative sampling efficiency of light traps varied slightly but significantly with mosquito abundance in villages with treated bed nets, but not in those without them. Nevertheless, the relationship between relative sampling efficiency and mosquito abundance did not differ significantly between the two types of village. Overall, there was insufficient evidence to show that the presence of treated nets altered the relative efficiency of light traps and any bias was only slight, and unlikely to be of any practical importance. Hence, it was concluded that light traps can be used as a surrogate for human bait catches in estimating biting rates of A. gambiae mosquitoes in the two communities.
Temporal variation of RAPD–PCR phenotype composition of the grain aphid Sitobion avenae (Hemiptera: Aphididae) on wheat: the role of hydroxamic acids
Authors: Figueroa C.C. , Loayza-Muro R. , Niemeyer H.M. 
Published: August 2023

AbstractHydroxamic acids (Hx) contained in wheat are active mutagens which play an important role in the defence of the plant against aphids. Random amplified polymorphic DNA–polymerase chain reaction (RAPD–PCR) dominant markers were used to assess genetic variability in the aphid Sitobion avenae (Fabricius) in relation to hydroxamic acid levels in their host-plants. Colonies of aphids belonging to a single RAPD–PCR profile were grown on different host-plants differing in their Hx content under greenhouse conditions. The RAPD–PCR phenotypic pattern showed the appearance of two new RAPD–PCR variants after four to five generations of exposure to wheat cv. Chagual (high Hx levels), one after exposure to wheat cv. Huayún (low Hx levels), and none after exposure to oat (lacking Hx). Differential appearance of new RAPD–PCR aphid phenotypes also occurred on field-grown wheat. While the overall phenotypic ‘richness’ diminished during the season, the number of RAPD–PCR phenotypes decreased on cv. Huayún and increased on cv. Chagual. The preferential appearance in the field and in the greenhouse of new RAPD–PCR phenotypes of S. avenae on cv. Chagual is discussed on the basis of mutagenesis induced by hydroxamic acids and by the products of their transformation within the aphid. Aphid abundance is interpreted in terms of antixenosis and antibiosis by hydroxamic acids. The appearance on cv. Chagual of phenotypes first detected on cv. Huayún was accounted for by intercrop migrations.
Tritrophic interactions between cabbage cultivars with different resistance and fertilizer levels, cruciferous aphids and parasitoids under field conditions
Authors: Kalule T. , Wright D.J. 
Published: August 2023

AbstractTritrophic interactions involving cabbage Brassica oleracea var. capitatacultivars ± fertilizer, Brevicoryne brassicae (Linnaeus) and Myzus persicae (Sulzer), and the parasitoids Diaeretiella rapae (M’cIntosh) and Aphidius sp. were conducted in 1998 and 1999. Brevicorne brassicaewas the dominant aphid species on all cultivars ± fertilizer, except for some treatments in late season 1998. Ruby Ball (red-leaved with antixenosis factors for B. brassicae alates) ± fertilizer was consistently less colonized by aphids in early stages of plant growth, although only significantly so compared with Derby Day (green-leaved, susceptible to aphids) without fertilizer for B. brassicae and Minicole (green-leaved with antibiosis factors for B. brassicae) with fertilizer for M. persicae. In early 1999, only B. brassicae was present and no significant differences between cultivars were seen. In the mid to late season 1998, the highest aphid infestations were usually found on Derby Day, although only significantly so for B. brassicae, in some treatments. In 1999, higher aphid infestations were observed on Derby Day in mid to late season and some significant differences were found for M. persicae as well as for B. brassicae. In both years, Ruby Ball had the greatest mummy:aphid ratios early season, with no consistent difference between the other cultivars. Later in the season, mummy:aphid ratios were generally highest on Minicole. Parasitism differed in seasonal occurrence and relative abundance. Diaeretiella rapae mummies were found earlier than Aphidius sp. There was evidence of a beneficial interaction between the degree of plant resistance and biological control in early to mid season.