bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of glycemic control on fetal hearts of pregestational diabetic women by tissue doppler and M‐mode imaging
Authors: Menekse Beser Dilek , Oluklu Deniz , Uyan Hendem Derya , Yildirim Muradiye , Turgut Ezgi , Sahin Dilek 
Published: July 2023

AbstractObjectiveTo determine whether changes in fetal heart function according to glycemic control in pregnant women with Type 1 and Type 2 diabetes using spectral tissue Doppler imaging (TDI) and M‐mode imaging.MethodsThis study included 68 pregestational diabetic women (DM) at 30–32 gestational weeks. All participants were divided into two groups: type 1(n = 17) and type 2(n = 51), and then these groups were divided into the subgroups as well‐controlled and poorly controlled, according to fasting glucose (FG) and 1‐h postprandial glucose (PPG) values. Cardiac parameters were compared for well‐ and poorly‐controlled groups with TDI and M‐mode imaging. The correlation of cardiac parameters with FG, PPG, and HbA1c values was evaluated. Their roles in predicting neonatal outcomes were also assessed.ResultsThickness measurements, early diastolic annular peak velocity (E’), late diastolic annular peak velocity (A’), tissue isovolumetric relaxation time (IRT’), and tissue myocardial performance index (MPI’) were increased in both poorly controlled groups. Tissue ejection time (ET') was significantly reduced in the poorly controlled groups, while tissue isovolumetric contraction time (ICT') was not significantly changed in any group. Tricuspid, mitral, and septal annular plane excursions (TAPSE, MAPSE, and SAPSE, respectively) were significantly decreased in all poorly controlled subgroups. E', E'/A’, MPI’, IRT', ET', and M‐mode imaging parameters significantly correlated with FG notably.ConclusionMaternal hyperglycemia leads to subtle changes in systolic and diastolic functions both in the interventricular septum and ventricles, so it is essential to ensure glycemic control in both Type 1 and Type 2 DM.
Outcomes among youth attending inpatient treatment for co‐occurring disorders
Authors: Rosenkranz Susan E. , Courtney Darren , Chen Sheng , Ma Clement 
Published: July 2023

AbstractAimAn emerging body of research is identifying effective outpatient integrated treatment approaches for youth with co‐occurring psychiatric and substance use disorders, though few studies exist examining inpatient treatment. The current study aimed to address this gap by examining response to treatment during admission to, and in the year following discharge from, a specialized inpatient program for youth with co‐occurring disorders.MethodsA single‐cohort longitudinal design examined change in adaptive functioning, mental health symptoms, and substance use frequency among N = 142 youth (69.1% female) aged 14–21 (M = 16.9, SD = 1.5) attending the program. Participants completed self‐report measures at admission, discharge, and 1‐, 6‐ and 12‐months post‐discharge.ResultsAnalyses indicated significant improvements in adaptive functioning, internalizing and externalizing symptoms, and substance use frequency during admission. There was some loss of gains in adaptive functioning over the 12‐months post‐discharge. Improvements were maintained in internalizing symptoms and substance use frequency, and improvements in externalizing symptoms continued over the 12‐months post‐discharge. There was no significant interaction between change in functioning and internalizing symptoms at admission or type of substance use disorder diagnosis. There was a significant interaction with externalizing symptoms, such that those with clinically significant levels of externalizing symptoms at admission experienced greater improvement in functioning, though the groups ended treatment with comparable functioning scores.ConclusionsThe results provide preliminary support for integrated treatment for co‐occurring disorders delivered in an inpatient setting. However, the results also reflect the significant needs of youth with co‐occurring disorders and the importance of ongoing care post‐discharge from intensive treatment settings.
Microbial redox cycling enhances ecosystem thermodynamic efficiency and productivity
Authors: Seto Mayumi , Kondoh Michio 
Published: July 2023

AbstractMicrobial life in low‐energy ecosystems relies on individual energy conservation, optimizing energy use in response to interspecific competition and mutualistic interspecific syntrophy. Our study proposes a novel community‐level strategy for increasing energy use efficiency. By utilizing an oxidation–reduction (redox) reaction network model that represents microbial redox metabolic interactions, we investigated multiple species‐level competition and cooperation within the network. Our results suggest that microbial functional diversity allows for metabolic handoffs, which in turn leads to increased energy use efficiency. Furthermore, the mutualistic division of labour and the resulting complexity of redox pathways actively drive material cycling, further promoting energy exploitation. Our findings reveal the potential of self‐organized ecological interactions to develop efficient energy utilization strategies, with important implications for microbial ecosystem functioning and the co‐evolution of life and Earth.
What's going to be on the menu with global environmental changes?
Authors: Hallam Jane , Harris Nyeema C. 
Published: July 2023

AbstractOngoing anthropogenic change is altering the planet at an unprecedented rate, threatening biodiversity, and ecosystem functioning. Species are responding to abiotic pressures at both individual and population levels, with changes affecting trophic interactions through consumptive pathways. Collectively, these impacts alter the goods and services that natural ecosystems will provide to society, as well as the persistence of all species. Here, we describe the physiological and behavioral responses of species to global changes on individual and population levels that result in detectable changes in diet across terrestrial and marine ecosystems. We illustrate shifts in the dynamics of food webs with implications for animal communities. Additionally, we highlight the myriad of tools available for researchers to investigate the dynamics of consumption patterns and trophic interactions, arguing that diet data are a crucial component of ecological studies on global change. We suggest that a holistic approach integrating the complexities of diet choice and trophic interactions with environmental drivers may be more robust at resolving trends in biodiversity, predicting food web responses, and potentially identifying early warning signs of diversity loss. Ultimately, despite the growing body of long‐term ecological datasets, there remains a dearth of diet ecology studies across temporal scales, a shortcoming that must be resolved to elucidate vulnerabilities to changing biophysical conditions.
Predicting recurrence in pancreatic neuroendocrine tumours: role of ARX and alternative lengthening of telomeres (ALT)
Authors: Neyaz Azfar , Crotty Rory , Rickelt Steffen , Pankaj Amaya , Stojanova Marija , Michelakos Theodoros P , Sekigami Yurie , Kontos Filippos , Parrack Paige H , Patil Deepa T , Heaphy Christopher M , Ferrone Cristina R , Deshpande Vikram 
Published: July 2023

BackgroundWhile many pancreatic neuroendocrine tumours (PanNET) show indolent behaviour, predicting the biological behaviour of small nonfunctional PanNETs remains a challenge. Nonfunctional PanNETs with an epigenome and transcriptome that resemble islet alpha cells (ARX‐positive) are more aggressive than neoplasms that resemble islet beta cells (PDX1‐positive). In this study, we explore the ability of immunohistochemistry for ARX and PDX1 and telomere‐specific fluorescence in situ hybridisation (FISH) for alternative lengthening of telomeres (ALT) to predict recurrence.MethodsTwo hundred fifty‐six patients with PanNETs were identified, and immunohistochemistry for ARX and PDX1 was performed. Positive staining was defined as strong nuclear staining in >5% of tumour cells. FISH for ALT was performed in a subset of cases.ResultsARX reactivity correlated with worse disease‐free survival (DFS) (P = 0.011), while there was no correlation between PDX1 reactivity and DFS (P = 0.52). ALT‐positive tumours (n = 63, 31.8%) showed a significantly lower DFS (P < 0.0001) than ALT‐negative tumours (n = 135, 68.2%). ARX reactivity correlated with ALT positivity (P < 0.0001). Among nonfunctional tumours, recurrence was noted in 18.5% (30/162) of ARX‐positive tumours and 7.5% (5/67) of ARX‐negative tumours. Among WHO grade 1 and 2 PanNETs with ≤2 cm tumour size, 14% (6/43) of ARX‐positive tumours recurred compared to 0 of 33 ARX‐negative tumours and 33.3% (3/9) ALT‐positive tumours showed recurrence versus 4.4% (2/45) ALT‐negative tumours.ConclusionImmunohistochemistry for ARX and ALT FISH status may aid in distinguishing biologically indolent cases from aggressive small low‐grade PanNETs, and help to identify patients who may preferentially benefit from surgical intervention.
Kapoor, Ria. Making Refugees in India. Oxford University Press. pp.272
Authors: Lahiri Sangbida 
Published: July 2023

AbstractRia Kapoor's book, Making Refugees in India, explores the history of refugees in India, tracing the way the figure of ‘refugee’ makes its appearance in the subcontinent since colonial times. The motivation for the book stems from the Citizen Amendment Act passed in the Indian Parliament in 2019, and through the book, Kapoor explores the past histories and the struggles of refugees in independent India for last seventy‐five years. Through the historicizing of the concept of refugee, Kapoor touches on various periods of history within the subcontinent.
Climate, floods, and migration in Pakistan
Authors: Kamal Ahsan 
Published: July 2023

AbstractThis commentary offers a glimpse into the complex landscape of climate‐induced migration in rural Pakistan. By shedding light on the interplay between gradual ecological shifts and rapid climate shocks, it exposes the misalignment between climate policies and the mobility strategies of marginalized communities. The vulnerabilities of rural Pakistanis facing climate and ecological shocks, like the 2022 floods, are rooted in the historical mismanagement of land and water commons. The current focus on infrastructure‐heavy interventions does not address the rigidity introduced by colonial and postcolonial interventions, which have undermined the seasonal mobility and fluidity of pastoralists, peasants, fishers and the landless in rural Pakistan. Thinking climate and migration together requires us to consider the socio‐economic constraints and drivers of migration, burgeoning political conflicts, and the ecological consequences of infrastructure‐heavy climate adaptation strategies by global investors and the Pakistani state.
Analysing Creative Design Process: A Set of Tools to Understand Activity in its Socio‐cultural and Historic Context
Authors: Saris Brenda , Doyle Stephanie , Loveridge Judith 
Published: July 2023

AbstractPrevious theoretical frameworks used to research and explain creative design processes tend to privilege individual expression and not address the context in which the process occurs. This is problematic due to the ways in which creative activities are embedded in and shaped by socio‐cultural and historic contexts. In this article we focus on the ways in which cultural historic activity theory (CHAT) and its analytical activity systems can be used to reveal creative processes in context. We draw on the tools and concepts of CHAT and data from a study of visual communication design (VCD) students and lecturers situated within a transnational higher education (TNHE) context at a university in China. An analytical framework was constructed to research practices used in creative design process learning. The dynamic nature of CHAT offers design process research methods a set of analytical tools to capture the powerful parts played by artifacts and interactions within specific sociocultural and historic learning contexts.
Surveillance and patient safety in nursing research: A bibliometric analysis from 1993 to 2023
Authors: Doyon Odette , Raymond Louis 
Published: July 2023

AbstractAimsTo identify and characterize the thematic foci, structure and evolution of nursing research on surveillance and patient safety.DesignBibliometric analysis.MethodsBibliometric methods were employed to analyse 1145 articles, using Bibliometrix and VOSviewer software.Data SourceThe Scopus bibliographic database was searched on April 7, 2023.ResultsA keyword co‐occurrence analysis found the most frequently occurring keywords to be: patient safety, nursing, nurses, adverse events, monitoring, critical care, quality improvement, vital signs, safety, alarm fatigue, education, nursing care, surveillance, clinical alarms, failure to rescue, evidence‐based practice, acute care, clinical deterioration, communication, intensive care. Network mapping, clustering and time‐tracking of the keywords revealed the focal themes, structure and evolution of the research field.ConclusionBy assessing critical areas of the nursing research field, this study extends and enriches the current discourse on surveillance and patient safety for nursing researchers and practitioners. Critical challenges still have to be met by nurses, however, including the failure to rescue deteriorating patients. Further knowledge and understanding of surveillance and patient safety must be successfully translated from research to practice.Implications for the ProfessionThis study highlights the gaps in nursing knowledge with regard to surveillance and patient safety and encourages nursing professionals to turn to evidence‐based surveillance practices.ImpactIn addressing the problem of surveillance and its effect on patient safety, this study found that, in most clinical care settings, preventing failures to rescue and adverse patient outcomes still remains a challenge for the nursing profession. This study should have an impact on nursing academics' future research themes and on nursing professionals' future clinical practices.Reporting MethodRelevant EQUATOR guidelines have been adhered to by employing recognized bibliometric reporting methods.
Repeated asynchronous evolution of single‐species endemics of ivies (Hedera L.) in Macaronesian archipelagos
Authors: Gallego‐Narbón Angélica , Alonso Alejandro , Valcárcel Virginia , Fernández‐Mazuecos Mario 
Published: July 2023

AbstractAimEvolutionary studies of oceanic island endemics are usually focused on lineages that have experienced in situ radiation, while those that speciated once on the island or archipelago but have not further diversified (single‐species endemics) remain understudied. The Macaronesian archipelagos, in the Atlantic Ocean, are home to significant numbers of single‐species endemics. The genus Hedera L. (12 species) includes three single‐species endemics from three Macaronesian archipelagos with putatively independent origins. Here, we tested the role of phylogenetic niche conservatism in their evolution. To that end, we (1) reconstructed the spatio‐temporal origin of Macaronesian ivies using phylogenomics, and (2) assessed the role of climatic niche during their colonization and speciation.LocationAzores, Canary Islands, Madeira, western Mediterranean.TaxonHedera spp.MethodsWe used 166 samples representing all Hedera species to generate genotyping‐by‐sequencing (GBS) libraries and performed time‐calibrated phylogenomic and biogeographic analyses. Climatic preferences and climatic niche evolution were assessed using a geo‐referenced database of the western ivy species (2,297 records).ResultsIndependent and asynchronous colonization and speciation were estimated for the three Macaronesian ivies, resulting in different degrees of phylogenetic and climatic niche differentiation: H. canariensis displayed an early divergence (7.5–12 Ma) and high phylogenetic and niche isolation; H. azorica had intermediate phylogenetic isolation and niche divergence from its closest relative H. helix (4.4–6.8 Ma) and H. maderensis was embedded within the climatically similar H. iberica (2.8–4.6 Ma). A strong phylogenetic signal was suggested for climatic niche in the western clade of Hedera, where the three Macaronesian ivies are placed.Main ConclusionsThe three Macaronesian ivies represent the evolutionary stages leading to the emergence of single‐species island endemics. Climatic niche conservatism appears to be involved in the evolution of single‐species endemics, first by facilitating island colonization, and then by limiting in situ diversification.
Comparison of Check‐All‐That‐Apply and Adapted‐Pivot‐Test methods for wine sensory characterization with a panel of untrained students
Authors: Nougarède Sylvain , Diot Alice , Maza Elie , Samson Alain , Olivier‐Salvagnac Valérie , Caillé Soline , Geffroy Olivier , Chervin Christian 
Published: July 2023

AbstractThe Check‐All‐That‐Apply (CATA) method was compared with the Adapted‐Pivot‐Test (APT) method, a recently published method based on pair comparisons between a coded wine and a reference sample, called pivot, and using a set list of attributes as in CATA. Both methods were compared using identical wines, correspondence analyses and Chi‐square test of independence, and very similar questionnaires. The results showed that CATA was more robust and more descriptive than the APT with 50–60 panelists. The p‐value of the Chi‐square test of independence between wines and descriptors dropped below 0.05 around 50 panelists with the CATA method, when it never dropped below 0.8 with the APT. The discussion highlights differences in settings and logistics which render the CATA more robust and easier to run. One of the objectives was also to propose an easy set‐up for university and food industry laboratories.Practical ApplicationsOur results describe a practical way of teaching and performing the CATA method with university students and online tools, as well as in extension courses. It should have applications with consumer studies for the characterization of various food products. Additionally, we provide an improved R script for correspondence analyses used in sensory characterization and a Chi‐square test to estimate the number of panelists leading to robust results. Finally, we give a set of data that could be useful for sensory and statistics teaching.
Voting status of people with an intellectual disability in four French–speaking cantons of Switzerland: A survey
Authors: Fontana‐Lana Barbara , Petragallo Isabelle , Bach Manon , Petitpierre Geneviève 
Published: July 2023

AbstractSwitzerland is a direct democracy, so its citizens are very often called to vote on various issues. Gaining voter status is, however, a very difficult process for many Swiss citizens with intellectual disability. This research describes the voting status of people with intellectual disability in four French–speaking cantons of Switzerland. It tries to understand systemic or structural factors, such as the guardianship legislation and the legal frameworks, that might have an impact on the voting status of these people. Three hundred individuals with intellectual disability (18–72 years) took part in the study. They were recruited in 11 facilities through a full selection or a letter‐cluster sampling procedure depending on the age group. A questionnaire for each participant was anonymously completed by a support person in the facilities. The questionnaire was constructed with the assistance of self–advocates with intellectual disability, as well as that of people with various roles in decisions regarding voting rights, or providing support to people with intellectual disability, in the participating cantons. Descriptive analyses have been used. The results show that on average slightly more than one person with intellectual disability out of two received voting material, and about one out of two used it. Non‐receipt of voting material is significantly linked to general curatorship, higher financial allowance, living in less independent conditions and/or working in the most protective sectors. People who use their rights more are those who live in more protective environments. Having an intellectual disability implies a higher risk of being deprived of one's political rights, even when the law does not systematically prescribe such a restriction. Even a tailor‐made gradual guardianship system can result in rigid applications of the law, characterized by illegitimate deprivation of rights, such as the right to vote.
Communicative action, a path through the dissonance between nursing and corporate healthcare values
Authors: Buss Julia , Arnold Darrell 
Published: July 2023

AbstractThere is tension in the US healthcare system due to conflicting goals of maximizing the public's health and at the same time ensuring shareholder profit among the many private organizations that provide care to those in need. As a result, nurses (often the frontline workers in this mixed public/private and economized system) may experience dissonance between their professional values and the capitalistic values embodied in the healthcare system. Beyond the workplace, nurses are also committed to championing health and wellness, to advocating for social justice, and driving health policy. Yet, constrained by the conflicts between neoliberal values in an economized system and the values of care that inspire many to join the healthcare profession, nurses may lose the ability to live up to their moral ideals, to champion social justice, and to improve public health outcomes. In this paper, we use the critical theory of Juergen Habermas to explore these tensions and to suggest a path forward for nurses. We suggest that by engaging in dialog with each other and the public, and working for greater inclusivity, nurses can find ways to deconstruct ideologies inherent in our current healthcare system, to consider alternatives, and liberate healthcare from the dominance of market forces.
Interleukin‐38: A crucial player in periodontitis
Authors: Korkmaz Hilal , Hatipoğlu Mükerrem , Kayar Nezahat Arzu 
Published: July 2023

AbstractBackgroundThe objective of this study was to compare the levels of gingival crevicular fluid (GCF), salivary, and serum matrix metalloproteinase‐9, interleukin (IL)‐17, IL‐36γ, and IL‐38 in individuals with healthy periodontium, gingivitis, and periodontitis and to evaluate their correlations with clinical periodontal parameters.Materials and MethodsNinety systemically healthy and nonsmoking volunteers divided into a healthy (H) group (n = 30), a gingivitis (G) group (n = 30), and a periodontitis (P) group (n = 30) were included in this study. Clinical periodontal parameters of volunteers were recorded, and GCF, unstimulated saliva, and serum samples were collected. Data analysis was done with enzyme‐linked immunosorbent assays. The Kruskal–Wallis test and Bonferroni correction were used for multiple comparisons and post hoc statistical analyses.ResultsThe group H had significantly lower clinical parameters than the group P (p < 0.001). GCF and salivary IL‐36γ and IL‐38 levels were significantly higher in the group P than in the H and G groups (p < 0.05). Positive correlations between biochemical findings and clinical periodontal parameters were observed.ConclusionsIL‐36γ and IL‐38 levels in GCF, saliva, and serum correlate with clinical periodontal parameters and may play a role in determining the activity of periodontitis.