bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH PENGEMASAN VAKUM DAN NON VAKUM TERHADAP KUALITAS BEKASAM INSTAN IKAN MAS (Cyprinus carpio) SELAMA PENYIMPANAN SUHU RUANG
Authors: Wahyuni Novita Nur , Rianingsih Laras , Romadhon Romadhon 
Published: May 2023

Bekasam merupakan hasil fermentasi secara tradisional dari ikan air tawar yang ditambahkan garam dan karbohidrat. Bekasam harus segera diolah dan dikonsumsi karena memiliki masa simpan yang cukup pendek. Bekasam instan merupakan inovasi bekasam yang diolah dengan cara pengovenan sehingga lebih tahan lama. Tujuan penelitian ini adalah untuk mengetahui pengaruh pengemasan secara vakum dan non vakum terhadap kualitas bekasam instan ikan mas selama penyimpanan suhu ruang. Metode penelitian yang digunakan adalah experimental laboratories menggunakan Rancangan Acak Lengkap (RAL) pola faktorial. Perlakuan meliputi pengemasan secara vakum dan non vakum serta lama penyimpanan (minggu ke- 0, 1, 2, 3) tiga kali ulangan. Analisis data menggunakan uji ANOVA dan jika sig < 0,05 dilanjut dengan uji Beda Nyata Jujur (BNJ). Hasil penelitian menunjukkan bahwa bekasam dengan kemasan non vakum sudah tidak layak konsumsi pada minggu ke-2 dengan nilai hedonik 5,68 ± 0,47; kadar air 50,86 ± 1,55; kadar protein 32,13 ± 2,14; pH 5,4 ± 0,05; TVBN 66,63 ± 2,21; TPC (log CFU/g) 7,32 ± 0,09. Bekasam dengan kemasan vakum sudah tidak layak konsumsi pada minggu ke-3 dengan nilai hedonik 5,56 ± 0,47; kadar air 43,68 ± 0,34; kadar protein 33,13 ± 0,77; pH 5,25 ± 0,05; TVBN 64,15 ± 1,37; TPC (log CFU/g) 6,84 ± 0,09.
STRUKTUR KOMUNITAS PERIFITON, NITRAT, DAN FOSFAT DI SUNGAI KALIGARANG, SEMARANG
Authors: Lestari Ambar , Sulardiono Bambang , Rahman Arif 
Published: May 2023

Sungai Kaligarang merupakan sungai yang melintasi Kota Semarang dan memegang peranan penting bagi masyarakat disekitarnya. Ekosistem sungai merupakan habitat bagi biota air yang keberadaannya sangat dipengaruhi oleh lingkungan sekitarnya. Aktivitas manusia sangat mempengaruhi kualitas air sungai, yang akan berdampak pada jumlah biota di sungai dan menurunkan kualitas sungai. Salah satu biota yang dijadikan bioindikator kualitas perairan adalah perifiton. Tujuan penelitian ini adalah untuk mengetahui struktur komunitas perifiton serta hubungan kepadatan perifiton dengan nitrat dan fosfat di Sungai Kaligarang. Penelitian ini dilaksanakan pada bulan November 2019 di Sungai Kaligarang, Semarang. Penelitian ini menggunakan metode purposive sampling yang dilakukan di 3 stasiun. Stasiun 1 dekat pemukiman warga, stasiun 2 area perhutanan, dan stasiun 3 dekat perkebunan. Analisis data yang digunakan adalah regresi linier berganda. Hasil yang diperoleh yaitu 24 genera perifiton dari kelas Bacillariophyceae 14 genera, kelas Chlorophyceae 8 genera, dan kelas Cyanophyceae 2 genera. Rata-rata kepadatan perifiton di Sungai Kaligarang adalah 141.412 individu/cm2. Kandungan nitrat berkisar antara 6,94-8,82 mg/L dan fosfat berkisar antara 0,24-0,42 mg/L. Analisis regresi linier berganda didapatkan nilai korelasi 0,499 yang menunjukkan terdapat hubungan sedang antara kepadatan perifiton dengan nitrat dan fosfat.
Hubungan Pengumpulan Data Surveilans COVID-19 Dengan Karakteristik Petugas Surveilans Covid-19 Di Kota Semarang Tahun 2021
Authors: Puspitasari Ayu , Martini Martini , Wurjanto Moh. Arie , Yuliawati Sri 
Published: May 2023

Kegiatan surveilans Covid-19 merupakan sebuah upaya pencegahan dan pengendalian pandemi Covid-19 tujuannya yaitu untuk melihat bagaimana surveilans Covid-19 telah dilaksanakan, dalam surveilans terdapat pengumpulan data, pengumpulan data diperlukan sebagai bahan pertimbangan dalam meningkatkan pelaksanaan surveilans agar dapat berjalan secara optimal. Penelitian ini merupakan penelitian deskriptif dengan pendekatan cross sectional besar sampel dalam penelitian ini adalah 37 petugas surveilans teknik pengambilan sampel adalah total sampling pengumpulan data dilakukan dengan menggunakan kuesioner, analisis data menggunakan analisis bivariat (uji statistik Chi-Square). Hasil penelitian menunjukkan bahwa ada hubungan antara jenis kelamin (p=0,021), pendidikan (p=0,042), masa kerja (p=0,000), beban kerja (p=0,049), dan riwayat pelatihan (p=0,015) dengan kinerja tenaga kesehatan surveilans COVID-19 di Puskesmas Kota Semarang. Kesimpulan nya yairu dari penelitian ini diketahui bahwa ada hubungan antara jenis kelamin, pendidikan, masa kerja, beban kerja dan riwayat pelatihan kerja dengan kinerja tenaga kesehatan di Puskesmas Kota Semarang. Surveilans Covid-19 di Kota Semarang yang sudah terlaksana dengan baik adalah pengumpulan data kasus surveilans COVID-19 yang dibuktikan dengan kinerja yang baik oleh petugas surveilans COVID-19 sebesar 62,2%. Kesimpulan dari penelitian ini, Implementasi komponen surveilans berjalan dengan baik dan sebagai rekomendasi yang diberikan kepada Dinas Kesehatan Kota dan Pusat Kesehatan Masyarakat. Perlu mempertimbangkan kembali beban kerja dan pelatihan lebih lanjut bagi petugas untuk menghasilkan pengendalian penyakit yang lebih baik.Kata Kunci : COVID-19, Surveilans, Petugas Surveilans COVID-19
Kajian Pengaruh Pemanasan terhadap Aktivitas Antioksidan Buah Mengkudu (Morinda Citrifolia) sebagai Alternatif Sumber Pangan Fungsional
Authors: Kurniati Dian 
Published: May 2023

Dewasa ini, minat akan makanan fungsional menggunakan antioksidan berbasis tumbuhan terus meningkat. Salah satu sumber antioksidan alami adalah buah mengkudu (Morinda citrifolia) yang banyak dikonsumsi dalam bentuk jus, fruit leather, serbuk, kapsul sebagai sumber antioksidan alami, namun belum banyak penelitian yang mempelajari aktifitas antioksidan, fenolik dan flavonoid total dari buah mengkudu segar yang mengalami pemanasan. Penelitian ini bertujuan untuk mengetahui pengaruh proses pemanasan sebagai informasi untuk memperoleh bahan baku dari mengkudu yang memiliki aktifitas antioksidan tertinggi. Buah mengkudu diberi pemanasan pada suhu 40, 60, 80, dan 100°C serta suhu ruang (RT), kemudian dimaserasi dengan etanol dan dipekatkan hingga diperoleh ekstrak etanol. Aktivitas antioksidan ditentukan dengan metode DPPH (2,2-difenill-1-pikrilhidrazil). Kandungan fenolik total dan flavonoid total ditentukan dengan teknik spektrofotometri. Hasil pengujian menunjukkan bahwa fraksi dengan suhu pemanasan 60°C menunjukkan aktivitas antioksidan paling tinggi dengan nilai 365,56 mg/L yang didukung dengan nilai fenolik total tertinggi sebesar 1,21%. Dimana nilai flavonoid total tertinggi ditunjukkan oleh fraksi tanpa suhu pemanasan (RT) dengan nilai 0,06%.
Energy consumption, mechanical and metallographic properties of cryogenically treated tool steels
Authors: Savaş Ahmet Fevzi , Öktem Hasan , Öztürk Burak , Uygur İlyas , Küçük Özkan 
Published: May 2023

Abstract
This article examines energy consumption, microstructure, mechanical properties, and the change in the wear amount during the machining of GGG-42 cast iron material with two types of guide cutting tool produced by powder metallurgy and casting method The tap. tool samples used as cutting tool material were first subjected to the traditional hardening process and then to two different cryogenic treatments (24–16 h) at −90°C. The internal structures of the guide samples obtained from conventional heat treatment and cryogenic treatment were examined with an optical microscope and Scanning Electron Microscope. The hardness changes were checked with Vickers measurement method. The wear amount forming after the threading process was measured with CLEMEX program in a light microscope. In addition, by measuring the current amount drawn during the machining of the cast iron with guide cutter tools, instantaneous power consumption during cutting and power consumption during chip removal were calculated. The application of heat treatment and cryogenic process increased the hardness of the guides. Moreover, the power consumption during the chip removal was also seen to increase. This can be commented that cutting tools produced with powder metallurgy perform better than the cutting tools produced via casting and 30% energy saving.
Novel multilevel inverter topology with low switch count
Authors: Lotfi Amir , Maalandish Mohammad , Aghaei Amir , Samadian Ataollah , Fathollahi Arman , Hosseini Seyed Hossein , Khooban Mohammad-Hassan 
Published: May 2023

AbstractThis paper aims to introduce a new multilevel inverter topology less number of switches and gate drivers with a hybrid control method. In the proposed topology three kinds of voltage sources are utilized in the topology. A combination of these voltage sources, switches, and two H-bridges derived a new topology. Moreover, combining the nearest level and pulse width modulation created an efficient way to control the proposed topology which is described in this paper. Equations to determine the number of components and total standing voltage of the proposed multilevel is presented. A comprehensive comparison between the proposed topology and other best topologies is made. Additionally, the simulation results which are obtained by PSCAD/EMTDC and experimental results are in accordance with the theory. The proposed multilevel inverter with a hybrid control method has less number of switches, gate drivers, and low THD.
Genetic and clinical features of patients with intrahepatic cholestasis caused by citrin deficiency
Authors: Sun Wenjun , Zhang Xiaoxi , Su Hang , Wang Xiaoxia , Qin Fang , Gong Xiangling , Wang Bo , Yu Fei 
Published: May 2023

Abstract

Objectives
Citrin deficiency (CD) is an autosomal recessive disease caused by mutations of the SLC25A13 gene, plasma bile acid profiles detected by liquid chromatography-tandem mass spectrometry (LC-MS/MS) could be an efficient approach for early diagnosis of intrahepatic cholestasis. The aim of this study was to investigate the genetic testing and clinical characteristics of a series of patients with CD, and to analyse plasma bile acid profiles in CD patients.

Methods
We retrospectively analysed data from 14 patients (12 males and 2 females, age 1–18 months, mean 3.6 months) with CD between 2015 and 2021, including demographics, biochemical parameters, genetic test results, treatment, and clinical outcomes. In addition, 30 cases (15 males and 15 females, age 1–20 months, mean 3.8 months) with idiopathic cholestasis (IC) served as a control group. Plasma 15 bile acid profiles were compared between the CD and IC groups.

Results
Eight different mutations of the SLC25A13 gene were detected in the 14 patients diagnosed with CD, of which three novel variants of the SLC25A13 gene were investigated, the c.1043C>T (p.P348L) in exon11, the c.1216dupG (p.A406 Gfs*13) in exon12 and the c.135G>C (p.L45F) in exon3. More than half of the patients with CD had prolonged neonatal jaundice, which was associated with significantly higher alpha-fetoprotein (AFP) levels, hyperlactatemia and hypoglycemia. The majority of patients were ultimately self-limited. Only one patient developed liver failure and died at the age of 1 year due to abnormal coagulation function. In addition, the levels of glycochenodeoxycholic acid (GCDCA), taurocholate (TCA), and taurochenodeoxycholic acid (TCDCA) were significantly increased in the CD group compared with those in the IC group.

Conclusions
Three novel variants of the SLC25A13 gene were identified for the first time, providing a reliable molecular reference and expanding the SLC25A13 gene spectrum in patients with CD. Plasma bile acid profiles could be a potential biomarker for non-invasive early diagnosis of patients with intrahepatic cholestasis caused by CD.
Deep-learning-assisted reconfigurable metasurface antenna for real-time holographic beam steering
Authors: Ma Hyunjun , Kim Jin-Soo , Choe Jong-Ho , Park Q-Han 
Published: May 2023

Abstract
We propose a metasurface antenna capable of real-time holographic beam steering. An array of reconfigurable dipoles can generate on-demand far-field patterns of radiation through the specific encoding of meta-atomic states i.e., the configuration of each dipole. Suitable states for the generation of the desired patterns can be identified using iteration, but this is very slow and needs to be done for each far-field pattern. Here, we present a deep-learning-based method for the control of a metasurface antenna with point dipole elements that vary in their state using dipole polarizability. Instead of iteration, we adopt a deep learning algorithm that combines an autoencoder with an electromagnetic scattering equation to determine the states required for a target far-field pattern in real-time. The scattering equation from Born approximation is used as the decoder in training the neural network, and analytic Green’s function calculation is used to check the validity of Born approximation. Our learning-based algorithm requires a computing time of within 200 μs to determine the meta-atomic states, thus enabling the real-time operation of a holographic antenna.
Heuristic algorithms for understanding chemistry via simple quantities
Authors: Karen Pavel 
Published: May 2023

AbstractPeriodicity of elements is the basis of teaching and understanding inorganic chemistry. This review exemplifies simple rules and counting procedures as heuristic algorithms yielding often-dimensionless quantities that, as such or together with auxiliary parameters, allow us to predict not only the stoichiometry and bonding of compounds, but also some of their properties or reactions.
High‐resolution transcriptomic and epigenetic profiling identifies novel regulators of COPD
Authors: Schwartz Uwe , Llamazares Prada Maria , Pohl Stephanie T , Richter Mandy , Tamas Raluca , Schuler Michael , Keller Corinna , Mijosek Vedrana , Muley Thomas , Schneider Marc A , Quast Karsten , Hey Joschka , Heußel Claus P , Warth Arne , Winter Hauke , Serçin Özdemirhan , Karmouty‐Quintana Harry , Jyothula Soma SK , Patel Manish K , Herth Felix , Koch Ina , Petrosino Giuseppe , Titimeaua Alexandru , Mardin Balca R , Weichenhan Dieter , Jurkowski Tomasz P , Imbusch Charles D , Brors Benedikt , Benes Vladimir , Jung Birgit , Wyatt David , Stahl Heiko F , Plass Christoph , Jurkowska Renata Z 
Published: May 2023

AbstractPatients with chronic obstructive pulmonary disease (COPD) are still waiting for curative treatments. Considering its environmental cause, we hypothesized that COPD will be associated with altered epigenetic signaling in lung cells. We generated genome‐wide DNA methylation maps at single CpG resolution of primary human lung fibroblasts (HLFs) across COPD stages. We show that the epigenetic landscape is changed early in COPD, with DNA methylation changes occurring predominantly in regulatory regions. RNA sequencing of matched fibroblasts demonstrated dysregulation of genes involved in proliferation, DNA repair, and extracellular matrix organization. Data integration identified 110 candidate regulators of disease phenotypes that were linked to fibroblast repair processes using phenotypic screens. Our study provides high‐resolution multi‐omic maps of HLFs across COPD stages. We reveal novel transcriptomic and epigenetic signatures associated with COPD onset and progression and identify new candidate regulators involved in the pathogenesis of chronic lung diseases. The presence of various epigenetic factors among the candidates demonstrates that epigenetic regulation in COPD is an exciting research field that holds promise for novel therapeutic avenues for patients.
Percepción del riesgo de habitar en las inmediaciones de un sitio de disposición final, El Salto, México
Authors: Venegas Sahagun Beatriz Adriana , Mancha Gálvez Erika Elizabeth 
Published: May 2023

[Introduction]: The study of risk perception refers to the reflections and evaluations of people about the dangers to which they, their facilities and their environment are or could be exposed and make decisions about it. [Objective]: This research analyzes the risk perception of the communities Mesa de los Laureles and Fraccionamiento Nueva Vizcaya located in El Salto, Jalisco, Mexico, which are in the vicinity of the Los Laureles Sanitary Landfill. In addition to this, the spatial relationship between the location of people and diseases sensitive to contamination is examined. [Methodology]: A quantitative methodology was used, complemented with Geographic Information Systems, field trips and in-depth interviews. 101 surveys were carried out, the questionnaire was divided into four sections with 21 questions. Descriptive statistics and analysis with simple linear regression and chi-square were performed. [Results]: perceives the changes in their environment, and identifies related diseases, such as gastrointestinal, respiratory, and dermal . Statistical models indicate that illnesses could tentatively be minimized by 2.73% if homes were 2.55 meters further from the landfill. [Conclusions]: the population still perceives the risk from a very limited notion of space, which prevents it from reacting to the threat, likewise it has a portfolio of risks, where living in the vicinity of the landfill is not seen as a significant threat to his physical well-being, and assumes it as an acceptable risk.
Advanced in vivo fluorescence microscopy of neural electronic interface
Authors: Yang Qianru , Cui X. Tracy 
Published: May 2023

AbstractNeuroelectronic devices are essential tools in neuroscience research, diagnosis, and/or treatment of neurological diseases, as well as in neuro-prosthetics and brain–computer interfaces. Despite a long history of application, neuroelectronic devices are still facing challenges of unsatisfactory chronic stability and a lack of understanding of cellular mechanisms for recording and stimulation. To improve the information transfer between the neural tissue and electronic devices, a comprehensive understanding of the biological activities around the neural electrode is critical. In vivo fluorescent microscopy technologies are rapidly developing and have revolutionized our understanding of cellular dynamics in response to neural interfacing materials. Here, we will provide an overview of the in vivo fluorescence microscopy systems and imaging configurations for studying the neural electronic interface, as well as recent findings in biological mechanisms learned using these advanced optical imaging modalities. Finally, we will discuss the current challenges and future directions.
Graphical abstract
Identifying determinant factors influencing user’s behavioral intention to use Traveloka Paylater
Authors: Kurniasari Florentina , Prihanto Johny Natu , Andre Nikolaus 
Published: May 2023

The paylater payment feature is being widely discussed as an alternative payment system that offers simplicity and flexibility in settling digital business transactions with a 28 % to 38 % growth annually. Despite the popularity of Traveloka apps as the largest travel business platform that has been downloaded more than 100 million times, the number of Traveloka Paylater users is limited to only 8.6 % of the total users. The purpose of this study is to discuss what factors influence a user’s behavioral intention to use Traveloka Paylater.
The study involved 360 Traveloka user respondents over 17 years old who knew the Paylater model of payment but never use Traveloka PayLater.
The research found that computer self-efficacy affects perceived ease of use, security has an effect on trust, and social influence affects the behavioral intention to use Traveloka Paylater. Meanwhile, computer self-efficacy, perceived ease of use, perceived financial costs, security and trust do not have a positive influence on the behavioral intentions to use Traveloka Paylater.
Users with a higher level of computer self-efficacy find it easier to use the services and more trust the platform that has a higher level of security. Social media were proven to have the greatest impact on potential users by encouraging them to use Traveloka Paylater services. Since Traveloka Paylater services also offer some attractive promotions, including discount prices, users won’t mind if there will be extra charges.
The study shows that Traveloka Paylater becomes an attractive digital payment service due to its correlation with the credit system mechanism, which allows buyers to buy now but pay later using an installment plan. Traveloka Paylater shows promising growth since Indonesians are already familiar with the credit system. Since the majority of Traveloka Paylater users are the young generation, this method of payment will create hedonism of impulsive buying.
To extend the number of target users of the older generation, the study revealed the urgency to provide more integrated simple registration methods as well as create attractive live chat features, monitor the system regularly, and work with well-known influencers to increase literacy.
Improving printed products manufacturing technology using 3D printing
Authors: Rozum Tetiana , Zolotukhina Kateryna , Kushlyk-Dyvulska Olga , Petryshyna Anastasiya , Marchuk Ivanna 
Published: May 2023

The aim of the paper is to analyze the state of the printing industry in the current conditions, learn reproduction technologies on non-absorbent surfaces, and study modern technological processes of obtaining products based on 3D printing, which is the research object. The problem lies in the lack of general recommendations for using the above technology to produce printed products or their elements.
The main factors affecting the quality of finished products have been determined. The criterion to compare possible options for creating printed products was selected, namely, the examination method was considered. After processing the expert group summary, the consistency degree of opinions was determined using Kendall’s concordance coefficient. The most significant factor was identified, and further research is focused on it. Layer-by-layer deposition modeling was chosen as the technology for creating the test. Test fragments were developed, and materials and equipment to run the experiment were selected. A quantitative and qualitative assessment of the quality of 3D printing was carried out.
Following the conducted research, the shortcomings were taken into account, and a number of recommendations for further creation of the forthcoming high-quality product were made. Those recommendations refer to the optimal line width (1.5 points and more), typeface origin and font size (20 points and above) for the reproduction of text information, and thickness of the element base of printed products (minimum 2.5–3 mm).
The above recommendations allow a 3D printing product and its elements to achieve a remarkable quality level and visual appeal, as well as enable enterprises to use it as the basis of technological instructions for applying modern technologies.