bluuebunny/crossref_metadata_2025_split huggingface dataset:
Childhood maltreatment, shame, psychological distress, and binge eating: testing a serial mediational model
Authors: O’Loghlen Elyse , Galligan Roslyn , Grant Sharon 
Published: June 2023

Abstract
Objective
Despite evidence of causal relationships between childhood maltreatment and the development of binge eating disorder (BED), research on mediating mechanisms is lacking. The present study sought to understand the childhood maltreatment-binge eating relationship more fully by examining three types of shame (internal, external, body) and psychological distress as mediators in this relationship. There is evidence that shame and psychological distress are associated with both childhood maltreatment and binge eating pathology. It was hypothesised that shame stemming from childhood maltreatment would contribute to psychological distress, and to binge eating as a dysfunctional emotion regulation strategy, in a serial mediational model.

Method
Five hundred and thirty adults with self-reported binge eating symptoms completed an online survey, which included measures of childhood maltreatment, internal shame, external shame, body shame, psychological distress, and binge eating and other eating disorder symptoms.

Results
Path analyses showed three specific relationships: (1) a relationship between childhood emotional maltreatment and binge eating, which was serially mediated by internal shame and psychological distress; (2) a relationship between childhood sexual abuse and binge eating, which was mediated by body shame; and (3) a relationship between childhood physical maltreatment and binge eating, which was mediated by psychological distress. We also found a feedback loop, whereby binge eating might lead to increased overvaluation of body shape and weight (possibly due to increased weight) and then to an increase in internal shame and body shame. The final model showed excellent fit for the data.

Discussion
Findings extend our understanding of the link between childhood maltreatment and BED. Future intervention research should focus on examining the efficacy of interventions for different forms of childhood maltreatment, based on the key mediating factors.
Establishment of the management effectiveness assessment system of world natural heritage and empirical analysis—a case study of Fanjingshan
Authors: Yang Xiaoshuang , Mu Dijin , Hu Mingjian , Xiao Shizhen , Meng Jianan 
Published: June 2023

Abstract
Although there are more than 270,000 protected areas worldwide, there is currently little data on their protection and management effectiveness. As a kind of protected area, natural world heritage (WH) sites are small but represent some of the most important natural landscapes, covering a very large area. But natural WH is threatened by climate change, natural disasters and human activities. Therefore, to achieve the sustainable development of WH sites, it is very important to analyze the management status of WH sites. Based on this, the study extracts inspiration from Enhancing our Heritage Toolkit: Assessing management effectiveness of natural World Heritage sites. An assessment system of the management effectiveness (ME) of natural WH sites has been established, which has three dimensions (including management foundation, management measures, and management performances) and 21 indexes. The reliability and validity of the index system are tested using the exploratory factor analysis method, and the results show that the index system has good reliability and validity. Then principal component analysis and comprehensive assessment methods are used to analyze the ME of the Fanjingshan WH site. The results show that the management effectiveness of the Fanjingshan WH Site is relatively excellent, but it still faces challenges from tourism development and community participation.
Phytopathological and biochemical impacts of Trichoderma harzianum and certain plant resistance inducers on faba bean root rot disease
Authors: Masoud Hassan Mohamed , Megahed Allam Arafat , Helmy Mohamed Salah Eldin , Ibrahim Mahmoud Abdel-Aziz , El-Mougy Nehal Samy , Abdel-Kader Mokhtar Mohamed 
Published: June 2023

Abstract
Background
Faba bean attacked by soil-borne pathogens causing root rot disease. This disease has serious damage to both plant stand and produced yield. The present study aimed to evaluate effectiveness of the bioagents; Trichoderma harzianum and some plant resistance inducers as fungicide alternatives against root rot disease incidence at both pre- and post-emergence growth stages.

Results
Under open greenhouse conditions, the incidence of faba bean root rot in pre- and post-emergence growth phases was considerably reduced by using six inorganic salts and five antioxidants individually or combining with each other or with the bio-stimulator T. harzianum that exceeded the used fungicide, Rhizolex-T. Application of enervit agitated the highest significant defensive impact during pre-emergence stage versus root rot incidence (5.0%), followed by calcium sulfate and [cysteine + T. harzianum] (6.7%). At post-emergence stage, majority of the treatments completely suppressed (100.0%) root rot incidence, except vitamax plus and the fungicide (Rizolex-T) which expressed by 91.7 and 18.8%, respectively. Duplicate irrigations of 23 treatments after faba bean dressing improved the synthesis of different protein contents with the 2nd of which enhanced higher protein contents than the 1st one, except [T. harzianum + vitamin E + vitamin C + enervit + selenium + vitamax plus], [T. harzianum + vitamax plus] and cysteine. Disodium phosphate induced the highest catalase (CAT) activity (1820.8 and 1677.2 U/g FWt) after both irrigations. [T. harzianum + vitamax plus] and vitamin E induced the highest peroxidase (POD) activity 217.4 and 356.9 U/g FWt after 1st and 2nd irrigations, respectively. Disodium phosphate and [T. harzianum + vitamin E + vitamin C + enervit + selenium + vitamax plus] induced the highest chitinase (CHIA) activity 52.8 and 54.4 U/g FWt after 1st and 2nd irrigations, respectively. Application of disodium phosphate, calcium sulfate, potassium metabisulfite, sodium sulfate, cysteine, [cysteine + potash alum], enervit, vitamin E, [vitamin E + vitamin C + enervit + selenium + vitamax plus], [T. harzianum + enervit], [T. harzianum + selenium], [T. harzianum + vitamin E], [T. harzianum + vitamin E + vitamin C + enervit + selenium + vitamax plus] and vitamin C stimulated the formation of new protein bands on SDS-PAGE after the 2nd irrigation treatment.

Conclusions
Such treatments are considered good and environmentally safe alternatives against root diseases for getting rid of the negative effects of fungicides.
Five-year Outcome Between Radiofrequency Ablation vs Surgery for Unilateral Multifocal Papillary Thyroid Microcarcinoma
Authors: Yan Lin , Yang Zhen , Li Yingying , Li Xinyang , Xiao Jing , Jing HaoYu , Luo Yukun 
Published: June 2023

Abstract

Context
Ultrasound (US)-guided radiofrequency ablation (RFA) has been considered as an alternative to surgery or active surveillance for papillary thyroid microcarcinoma (PTMC). However, little is known about the long-term outcomes of RFA in comparison with surgery for unilateral multifocal PTMC.

Objective
This work aims to report the comparison between RFA vs surgery for unilateral multifocal PTMC over a more than 5-year follow-up period.

Methods
This was a retrospective study at a primary care center with a median follow-up period of 72.9 months. A total of 97 patients with unilateral multifocal PTMC were treated with RFA (RFA group, n = 44) or surgery (surgery group, n = 53). In the RFA group, patients were treated by a bipolar RFA generator and an 18-gauge bipolar RF electrode with a 0.9-cm active tip. In the surgery group, patients underwent thyroid lobectomy with prophylactic central neck dissection.

Results
During the follow-up, no statistically significant differences were found in disease progression (4.5% vs 3.8%; P = ≥.999), lymph node metastasis (2.3% vs 3.8%; P = ≥.999), persistent lesion (2.3% vs 0%; P = .272), and RFS rates (97.7% vs 96.2%; P = .673) in the RFA and surgery groups. Patients undergoing RFA had a shorter hospitalization (0 vs 8.0 [3.0] d; P &lt; .001), shorter procedure time (3.5 [2.4] vs 80.0 [35.0] min; P &lt; .001), lower estimated blood loss (0 vs 20.0 [15.0] mL; P &lt; .001), and lower costs ($1768.3 [0.1] vs $2084.4 [1173.8]; P = .001) than those in the surgery group. The complication rate in the surgery group was 7.5%, whereas none of the RFA-treated patients experienced any complications (P = .111).

Conclusion
This study revealed 6-year comparable outcomes between RFA and surgery for unilateral multifocal PTMC. RFA may be a safe and effective alternative to surgery in selected patients with unilateral multifocal PTMC.
Submerged Hostilities
Authors: Macauley Melissa 
Published: June 2023

Abstract
This article explores how the East Asian monsoon exacerbated social tensions in southeastern China and thereby fostered historical transformations in the region. By placing water at the center of late imperial Chinese social history, it demonstrates how disputes and animosities ebbed and flowed with the shifting of the seasonal winds. It also suggests the ways dynamic environmental events might complicate our notions of historical time.
Back to the future through the wormhole: Caenorhabditis elegans as a preclinical model
Authors: Caldwell Guy A. 
Published: June 2023

ABSTRACT
On the 15th Anniversary of Disease Models & Mechanisms as a trailblazing venue for the dissemination of discoveries pertaining to human health involving model systems, we celebrate the journey of this journal, as mirrored through the evolution of research using the nematode roundworm, Caenorhabditis elegans. Driven by the exponential growth of genomic data, worms have advanced from a basic research tool to precise and elegant models for disease and have yielded substantive insights into numerous human disorders. A harbinger of functional genomic analysis since the inception of RNA interference screening, the directed application of C. elegans for identification of disease-modifying factors has revealed new pathways and therapeutic targets to accelerate translational outcomes. Together with advances in gene editing, worm models are now ushering in the era of precision medicine with characteristic expedience.
Artificial intelligence-assisted quantification of COVID-19 pneumonia burden from computed tomography improves prediction of adverse outcomes over visual scoring systems
Authors: Grodecki Kajetan , Killekar Aditya , Simon Judit , Lin Andrew , Cadet Sebastien , McElhinney Priscilla , Chan Cato , Williams Michelle C. , Pressman Barry D. , Julien Peter , Li Debiao , Chen Peter , Gaibazzi Nicola , Thakur Udit , Mancini Elisabetta , Agalbato Cecilia , Munechika Jiro , Matsumoto Hidenari , Menè Roberto , Parati Gianfranco , Cernigliaro Franco , Nerlekar Nitesh , Torlasco Camilla , Pontone Gianluca , Maurovich-Horvat Pal , Slomka Piotr J. , Dey Damini 
Published: June 2023

Objective:
We aimed to evaluate the effectiveness of utilizing artificial intelligence (AI) to quantify the extent of pneumonia from chest CT scans, and to determine its ability to predict clinical deterioration or mortality in patients admitted to the hospital with COVID-19 in comparison to semi-quantitative visual scoring systems.

Methods:
A deep-learning algorithm was utilized to quantify the pneumonia burden, while semi-quantitative pneumonia severity scores were estimated through visual means. The primary outcome was clinical deterioration, the composite end point including admission to the intensive care unit, need for invasive mechanical ventilation, or vasopressor therapy, as well as in-hospital death.

Results:
The final population comprised 743 patients (mean age 65  ±  17 years, 55% men), of whom 175 (23.5%) experienced clinical deterioration or death. The area under the receiver operating characteristic curve (AUC) for predicting the primary outcome was significantly higher for AI-assisted quantitative pneumonia burden (0.739, p = 0.021) compared with the visual lobar severity score (0.711, p &lt; 0.001) and visual segmental severity score (0.722, p = 0.042). AI-assisted pneumonia assessment exhibited lower performance when applied for calculation of the lobar severity score (AUC of 0.723, p = 0.021). Time taken for AI-assisted quantification of pneumonia burden was lower (38 ± 10 s) compared to that of visual lobar (328 ± 54 s, p &lt; 0.001) and segmental (698 ± 147 s, p &lt; 0.001) severity scores.

Conclusion:
Utilizing AI-assisted quantification of pneumonia burden from chest CT scans offers a more accurate prediction of clinical deterioration in patients with COVID-19 compared to semi-quantitative severity scores, while requiring only a fraction of the analysis time.

Advances in knowledge:
Quantitative pneumonia burden assessed using AI demonstrated higher performance for predicting clinical deterioration compared to current semi-quantitative scoring systems. Such an AI system has the potential to be applied for image-based triage of COVID-19 patients in clinical practice.
Diagnostic value of contrast-enhanced ultrasound combined with MRI for cervical hyperplastic, tuberculosis-infected, and metastatic lymph nodes
Authors: Yu Xiulei , Zhang Wenzhi , He Ning , Su Dongming , Zhao Yang 
Published: June 2023

Objective: To explore the diagnostic value of contrast-enhanced ultrasound (CEUS) combined with magnetic resonance imaging (MRI) for cervical abnormal lymph nodes.
Methods: We retrospectively reviewed the clinical records of 150 patients undergoing lymph node examinations at Hangzhou Chest Hospital from January 2017 to December 2019. According to the characteristics of lymph nodes, the patients were divided into three groups: 45 patients had hyperplastic lymph nodes (HLNs; Group-A), 55 had lymph node tuberculosis (LNTB; Group-B), 50 had metastatic lymph nodes (MLN; Group-C). We compared the ultrasonic examination and MRI results between the groups, and compared the diagnostic value of CEUS alone and CEUS plus MRI.
Results: Lower resistance indexes (RI) for Groups-A and B than Group-C(P<0.05). Mixed blood flow type was predominant in Group-A, while the lymphohilum type was predominant in Group-B, and the marginal type was predominant in Group-C(P<0.05). The proportion of non-uniform types in Group-B was significantly higher than that in Groups-A and C(P<0.05). After enhancement, the proportions of non-uniform types in Groups-A and B were higher than Group-C(P<0.05). The results of MRI examination showed that positive reinforcement integral (PEI) and maximum slope of increase (MSI) values increased sequentially from Group-B to Group-A, and then to Group-C(P<0.05); while time to peak (TTP) values increased sequentially from Group-C to Group-A, and then to Group-B(P<0.05). The diagnosis accuracy of CEUS combined with MRI was significantly higher than that of CEUS alone(P<0.05). RI-PEI, RI-MSI, and RI-TTP showed high specificity and sensitivity in the diagnosis and differentiation of HLNs, LNTB, and MLNs(P<0.05).
Conclusion: CEUS combined with MRI can significantly facilitate the differential diagnosis between HLNs, LNTB, and MLNs. The two diagnosis methods combined improve the diagnosis accuracy of cervical lymph node diseases.
doi: https://doi.org/10.12669/pjms.39.4.7572
How to cite this: Yu X, Zhang W, He N, Su D, Zhao Y. Diagnostic value of contrast-enhanced ultrasound combined with MRI for cervical hyperplastic, tuberculosis-infected, and metastatic lymph nodes. Pak J Med Sci. 2023;39(4):950-955. doi: https://doi.org/10.12669/pjms.39.4.7572
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Diabetic Foot - treatment and prevention - literature review
Authors: Wąsiewicz Edward , Kuźniar Aleksandra , Szawica Dominik , Fularska Kamila , Oleszko Michał , Bernacki Radosław , Bernacki Piotr , Dutka Martyna , Zardzewiały Witold , Sobczak Fryderyk 
Published: June 2023

Introduction: Diabetic foot is a serious condition affecting large percentage of long term diabetics .Proper diabetic foot treatment, education and prevention can greatly influence quality of life of many diabetics who are at risk of developing this condition.
Aim of study: The purpose of the study was to review the latest literature on the most recent diabetic foot treatment, education and prevention.
Matherials and methods: A systemic review was conducted using Google Scholar, PubMed and ScienceDirect databases and the search was limited to studies published between 2000 and 2023. The search strategy was based on following terms: diabetic foot, diabetic neuropathy, diabetic ulcer, diabetic foot treatment.
Results: We found many different studies which show importance of gut microflora in various different ailments and diseases, we have also found many showing factors that influence intestinal microbiota composition.
Conclusions: diabetic foot is a severe complication of diabetes that requires a multidisciplinary approach to treatment. Prevention is essential, and patients should be educated on the importance of foot care and blood sugar control.With proper treatment and management, diabetic foot can be prevented and effectively treated.
Effects of Hospital-Acquired Conditions on Readmission Risk: The Mediating Role of Length of Stay
Authors: Bichescu Bogdan , Hilafu Haileab 
Published: June 2023

Problem definition: Hospital-acquired conditions (HACs) represent undesirable complications that occur during a hospital stay. HACs can compromise patient safety and care outcomes and result in unnecessary socio-economic costs. Although hospitals are expected to reduce the incidence of HACs, few studies have examined the implications of HACs on other clinical outcomes and measures of hospital performance. This study contributes to the literature by exploring the relationship between exposure to a set of target HACs, length of stay (LOS) performance, and 30-day readmission risk. Methodology/results: To estimate the effects of HACs, we conduct econometric analyses using patient-visit-level data for heart attack, heart failure, and pneumonia patients hospitalized in the U.S. state of Florida during 2010–2014. We define LOS performance as the deviation of LOS from the Geometric Mean LOS (GMLOS), a standard LOS set by the Centers for Medicare and Medicaid Services. First, we find that exposure to HACs leads to a 37% increase in the odds of readmission and a 79% increase in LOS. Second, an increase in LOS is associated with a decrease in readmission risk, and this decrease is stronger for patients exposed to HACs. Third, LOS performance mediates the HACs-readmission risk relationship, such that the increase in the readmission risk of a HAC patient can be fully suppressed by the patient’s LOS. Fourth, we find that for patients exposed to HACs, the benefits of a longer LOS are almost entirely capitalized when the LOS becomes 65% longer than the GMLOS. Managerial implications: We demonstrate that, when addressing the consequences of HACs, clinicians also face indirectly a trade-off between reducing readmissions and controlling costs. We proffer LOS as a potential mechanism under hospitals’ control for mitigating the adverse effects of HACs on readmission risk. Thus, this study offers guidance to clinicians having to decide when to discharge patients with exposure to HACs. Supplemental Material: The online appendix is available at https://doi.org/10.1287/msom.2022.0088 .
Making Sense of Corporate Purpose
Authors: Ocasio William , Kraatz Matthew , Chandler David 
Published: June 2023

Both the societal purpose of the corporation and an individual corporation’s sense of purpose have been subject to increased attention by business elites and academics alike. This special issue presents diverse viewpoints on these two distinct yet interrelated topics. In this introduction, we present the various contributions and build on their insights to develop our independent sensemaking of what corporate purpose entails. Thus, we define corporate purpose, at both the organizational and societal levels, as an institutionalized ideal, a historical, value-based aspiration guiding strategic decision making and practices. We interpret the current societal movement on corporate purpose as one rejecting the logic of shareholder capitalism and proposing sustainable capitalism in its place: an ideal for corporate purpose based on sustainable prosperity for society and its population. At the organizational level, corporate purpose can thus be articulated as a distinctive and meaningful intent to enhance the lives of people. We identify four strategic issues to consider in reconstituting a corporation’s purpose: corporate governance, strategic leadership, stakeholder engagement, and implementation. We conclude by highlighting the centrality of purpose to corporate strategy, an emphasis that was present in the field during its origins but one that got displaced under a logic of shareholder primacy.History: This paper has been accepted for the Strategy Science Special Issue on Corporate Purpose.
Factors influencing job satisfaction and anticipated turnover among intensive care nurses in Saudi Arabia
Authors: Al Bazroun Mohammed I , Aljarameez Faiza , Alhamza Roqaya , Ahmed Gasmelseed Y , Alhybah Fatimah , Al Mutair Abbas 
Published: June 2023

Background/Aims High staff turnover among nurses can be caused by a variety of factors, including job dissatisfaction. This study aimed to assess factors influencing job satisfaction and retention among intensive care nurses in three tertiary care hospitals in Saudi Arabia. Methods A multi-centre comparative cross-sectional study was carried out with 326 intensive care nurses working across three hospitals in Saudi Arabia. The Minnesota satisfaction questionnaire and the anticipated turnover scale were used to assess nurses' job satisfaction levels and intention to leave their organisation, with items scored on a 7-point Likert scale. Respondents' sociodemographic characteristics were also collected, including age, sex, nationality, salary, years of experience and shift length. Responses were analysed using the Statistical Package for Social Sciences version 25 to identify relationships between variables, with P values of ≤0.05 being considered statistically significant. Results Job satisfaction levels were generally low, with an average score of 58.34 out of 140. There was a significant inverse relationship between job satisfaction and intention to leave (P=0.001). Nurses who were not of Saudi Arabian nationality and those who earned less than 10,000 Saudi riyals had significantly higher levels of job satisfaction than Saudi Arabian nationals and those on higher salaries (P=0.001 and P=0.002 respectively). Other sociodemographic variables were not significantly associated with job satisfaction. Conclusions Job satisfaction needs to be improved among nurses working in intensive care units to prevent high staff turnover rates. Understanding how sociodemographic variables can affect job satisfaction may help healthcare managers and policymakers to implement effective, targeted strategies to improve staff retention.
Dentistry for adults with autism: a review for dental professionals
Authors: Emanuel Robert , Patel Parul , Farr Will , Anorson Nathan , Male Ian 
Published: June 2023

Autism is a lifelong neurodevelopmental disorder characterized by its impact on social communication and interaction. This article reviews its basic epidemiology, and provides advice based on current literature on how to manage behaviour, communication and prevention to provide optimal dental care. CPD/Clinical Relevance: This article will be of use to practitioners who may be involved in the care of patients with autism.