bluuebunny/crossref_metadata_2025_split huggingface dataset:
Estudio descriptivo de una muestra de pacientes con esquizofrenia residentes en el departamento de Boyacá, Colombia
Authors: Corredor Rozo Zayda Lorena , Sánchez Espinosa Mayely Paola , Rondón Lagos Sandra Milena , Páez Rojas Paola Liliana , Cortés Duque Carolina , Forero Castro Ruth Maribel 
Published: February 2023

La esquizofrenia, enfermedad multifactorial, tiene gran heterogeneidad genética y herencia compleja. En Boyacá, Colombia, se estudió un grupo de 20 pacientes esquizofrénicos (16 hombres y cuatro mujeres) y se establecieron las características socio-demográficas y clínicas y los factores genéticos y precipitantes. Se hicieron estudio citogenético y un análisis descriptivo de las variables cualitativas y cuantitativas. Hubo predominio del comienzo de la enfermedad en adultos jóvenes (promedio de edad en el momento de la aparición: 22,5 años). Predominaron la esquizofrenia paranoide (8/20) con modo de aparición progresivo (14/20). Se hallaron factores precipitantes en 15 pacientes: físicos en nueve, sociales en cinco y económicos en uno. Todos los cariotipos fueron normales. Los rasgos clínicos no se asociaron con las características socio-demográficas ni con los factores genéticos y precipitantes, lo que evidencia gran heterogeneidad en las formas de manifestación de la enfermedad. Se dio asesoría genética a los pacientes y sus familias y se les explicaron los resultados, el riesgo de recurrencias y el de padecer la enfermedad cuando se tiene un pariente afectado. Es necesario analizar una serie mayor de casos, para poder determinar si los factores evaluados influyen en el desarrollo de la enfermedad.
La asociación atorvastatina-meloxicam reduce el daño cerebral, atenuando la gliosis reactiva consecuente a embolismo arterial
Authors: Hernández Torres Marcela , Trujillo Almonacid Lina María , Céspedes Rubio Angel Enrique 
Published: February 2023

Introducción: el accidente cerebrovascular es la primera causa de discapacidad y la tercerade muerte en Colombia y en el resto del mundo y está asociado a enfermedades mentales yneurodegenerativas. Objetivo: determinar los efectos de la asociación atorvastatina-meloxicam sobre la gliosisreactiva en un modelo de isquemia cerebral por embolización arterial.Materiales y métodos: se utilizaron 56 ratas Wistar macho adultas, distribuidas en cuatrogrupos isquémicos y cuatro controles, además de otras 10 para determinar la distribucióny extensión del infarto, induciendo lesión en seis de ellas y simulación (sham) en las cuatro restantes. Los tratamientos fueron: placebo, atorvastatina (ATV), meloxicam (MELOX) y ATV + MELOX en isquémicos y simulados. Veinticuatro horas después de la isquemia se evaluó la actividad enzimática mitocondrial con trifeniltetrazolio (TTC) y a las 120 horas, la reactividad astrocitaria (anti-GFAP), mediante inmunohistoquímica convencional. Resultados: la asociación ATV+MELOX favoreció la modulación en la respuesta de los astrocitos protoplasmáticos y fibrosos del hipocampo y de la zona paraventricular, reduciendo su hiperreactividad. Conclusión: ATV y MELOX, aisladamente o asociados, reducen el daño cerebral atenuando la gliosis reactiva consecuente a la embolización arterial, lo que sugiere nuevos mecanismos de neuroprotección frente a la isquemia cerebral tromboembólica y abre nuevas perspectivas para su tratamiento temprano.
Trauma: una etiología inusual del pseudoquiste pulmonar
Authors: Vélez Tejada María Paulina , Roya Pabón Claudia Liliana , Morales Olga Lucía , Montoya Ochoa Francisco 
Published: February 2023

El Pseudoquiste pulmonar secundario a trauma cerrado de tórax, es una rara lesión cavitada en el parénquima pulmonar que carece de revestimiento epitelial. Es más frecuente en niños y adolescentes en quienes la pared torácica es menos rígida. Las manifestaciones clínicas usualmente son benignas y se resuelve espontáneamente de 2 a 4 meses luego del trauma. En este caso, presentamos la evolución de un paciente que tuvo un trauma cerrado de tórax en calidad de peatón, luego del cual aparece una lesión quística en el parénquima pulmonar, sin sintomatología muy evidente, con posterior resolución de la lesión en un paciente ya asintomático.
Alergia al látex en trabajadores de la salud
Authors: Fajardo-Zapata Álvaro L. 
Published: February 2023

Introducción: un problema común y creciente en el ámbito hospitalario es la hipersensibilidad a los antígenos del látex de caucho, ya que muchos productos, entre ellos los guantes, se fabrican con este material, con la consecuente posibilidad de producir alergia en quienes los usan.
Objetivo: averiguar si el personal de la salud de una clínica de cuarto nivel en Bogotá, Colombia, presenta alergia al látex relacionada con el uso de guantes.
Materiales y métodos: estudio descriptivo de corte transversal, con muestreo no probabilístico de tipo intencional en cuatro unidades hospitalarias. Se aplicó una encuesta a los participantes.
Resultados: 16 de las 26 personas (61,5%) que presentaban procesos alérgicos manifestaron algún tipo de reacción cuando tenían contacto con guantes de látex; el problema fue más significativo en el personal de enfermería que en los médicos.
Conclusiones: la exposición al látex de los guantes puede estar participando en la aparición de alergias de origen laboral en los trabajadores de la salud.
Malformación adenomatoidea quística: reporte de un caso
Authors: Ordóñez Gustavo , Morcillo Karen , Moreno Lina , Rojas Katerine 
Published: February 2023

El desarrollo pulmonar se puede afectar en cada una de las etapas del período prenatal, el desarrollo pulmonar se puede afectar en cada una de sus diferentes etapas dando lugar a enfermedades complejas que afectan la función respiratoria; es así como en la etapa pseudoglandular (semanas 7 a 15 de la gestación) puede producirse una proliferación anormal en los bronquiolos terminales dando origen a masas...
Un caso de fístula traqueoesofágica: diagnóstico y tratamiento
Authors: Lozano Sandra J. Moreno , Rodríguez Diego Andrés , Pinilla Adriana , Díaz Nataly X. Moreno 
Published: February 2023

CASO CLÍNICOPaciente de sexo masculino de 4 meses de edad, traído a la consulta por 15 días de tos seca persistente, en accesos, que le dificulta la alimentación. Historia de síndrome broncoobstructivo persistente, con múltiples agudizaciones...
Croatian as a Heritage Language in Argentina: Between Vulnerability and Linguistic Maintenance
Authors: Bilić Josip Bruno , Cuneo Paola , Franić Ivana 
Published: February 2023

In the South American context, migrant population makes up for a large portion of the population who, in most cases, stop using their heritage language. This work aims to present the results of a study that inquired about the status of the Croatian language as a heritage language in South America, and analized the tensions between linguistic displacement and maintenance. The analysis is focused on Argentina, where an estimated 250 000 to 500 000 people are from Croatian descent. The study is based upon a corpus of Croatian speech gathered from second- and third-generation migrants and from official and non-official records, gathered by the authors. Findings suggest that there are signs of linguistic attrition at the phonological, morphosyntactic, and lexical levels. They also suggest that identity and language aware­ness strengthening play a significant role in the maintenance of the ancestral language in this migrating context. The study contributes to the field of minority and endangered languages, and helps understand the dynamic pro­cesses influencing the vitality of heritage languages.
El diablo en las Artes Plásticas
Authors: Montero Carmona Guillermo Abel 
Published: February 2023

El diablo es un personaje que forma parte de la mitología judeocristiana, donde personifica los bajos instintos del ser humano. En las sagradas escrituras se lo presenta como un ángel cuya ambición le empuja a rebelarse contra Dios. Su origen sin embargo es mucho más antiguo que el propio cristianismo y recoge creencias anteriores a la religión judía, amalgamando bajo la personalidad diabólica a diversos dioses de los reinos vecinos, deidades por tanto contemporáneas del propio Yahvé.
Los artistas de la Era Cristiana, herederos de la plástica clásica, han representado muy frecuentemente la figura del diablo desde el periodo paleocristiano hasta la actualidad, dada la importancia de este personaje como antagonista de propio Dios y por el recurrente uso propagandístico que la Iglesia ha hecho de las imágenes. En ocasiones acogiéndose a fisonomías de carácter animal, ya reales ya imaginarias como, por ejemplo: la serpiente, el dragón, el simio, el reptil, el felino, el macho cabrío o la mosca, entre otros; o bien presentándolo con apariencia más o menos antropomórfica como son el Fauno, el ángel alado, un hibrido casi humano a los pies de San Miguel o la Inmaculada Concepción o incluso en forma de bebé diabólico. Los ejemplos que empleamos no son más que una muestra de la riquísima iconografía demoniaca presente en la tradición artística occidental.
YANGIN FARKINDALIK ÖLÇEĞİNİN GELİŞTİRİLMESİ: GEÇERLİK GÜVENİRLİK ÇALIŞMASI
Authors: ÇAP Hakan , BİÇER Turgay , TAVACIOĞLU Leyla 
Published: February 2023

Bu araştırmada, yolcu gemileri ve spor tesislerinde görevli personelin yangın acil durum farkındalık düzeylerini belirlemek amacıyla bir ölçek geliştirilmiştir. Literatür araştırması ve uzman görüşleri sonrası oluşturulan ölçek taslağı 402 gönüllü üzerinde uygulanmıştır. Faktör analizi sonucunda, ölçek 31 soruluk son halini kazanmıştır ve 6 alt boyut ortaya çıkmıştır. Test tekrar test uygulamasında birinci ve ikinci uygulama puanları arasında ki ilişki/korelasyon intra class correlation (ICC) ile hesaplanmış olup 0,926 bulunmuştur. Bu değer anketin güvenilir olduğunu ortaya koymaktadır. Anket güvenilirliğinde iç tutarlılık için Cronbach Alpha Katsayısı kullanılmıştır (Cronbach alpha= 0,957).
Temporal Variations of Seismicity Rates and Gutenberg–Richterb-Values for a Stochastic Declustered Catalog: An Example in Central Italy
Authors: Pastoressa Anna Eliana , Murru Maura , Taroni Matteo , Console Rodolfo , Montuori Caterina , Falcone Giuseppe , Di Stefano Raffaele 
Published: February 2023

AbstractOne important aspect of the seismicity is the spatiotemporal clustering; hence, the distinction between independent and triggered events is a critical part of the analysis of seismic catalogs. Stochastic declustering of seismicity allows a probabilistic distinction between these two kinds of events. Such an approach, usually performed with the epidemic-type aftershock sequence (ETAS) model, avoids the bias in the estimation of the frequency–magnitude distribution parameters if we consider a subset of the catalog, that is, only the independent or the triggered events. In this article, we present a framework to properly include the probabilities of any event to be independent (or triggered) both in the temporal variation of the seismic rates and in the estimation of the b-value of the Gutenberg–Richter law. This framework is then applied to a high-definition seismic catalog in the central part of Italy covering the period from April 2010 to December 2015. The results of our analysis show that the seismic activity from the beginning of the catalog to March 2013 is characterized by a low degree of clustering and a relatively high b-value, whereas the following period exhibits a higher degree of clustering and a smaller b-value.
PRINCIPLES OF THE ORGANIZATION OF THE SYSTEM OF PARTS OF SPEECH AND THEIR INTERPRETATION FROM AN INTERNAL PERSPECTIVE (BASED ON THE MATERIAL OF GERMAN AND RUSSIAN)
Authors: Averina Anna V. 
Published: February 2023

Aim.To introduce the concept of the level organization of the parts of speech system and to offer their interpretation from the speaker's internal perspective.Methodology.General scientific methods of analysis and synthesis, as well as linguistic methods of contextual and transformational analysis were used in this work.Results.The paper presents the concept of a level-based construction of the parts of speech system. The factors influencing the transitions of words from one part of speech to another are revealed. It is shown that the internal perspective finds its realization in parts of speech in the form of representation of phenomena and objects of the surrounding reality, as well as in the system of grammatical categories and in deicticity.Research implications.The study makes a certain contribution to the development of the concept of partial differentiation of words and criteria for their differentiation. The results obtained can be used in such academic course s as “General linguistics” and “Comparative typology of German and Russian languages”.
DENTAL ARCH WIDTH DETERMINATION WITH DEVELOPED COMPUTER PROGRAM AND INTRODUCTION OF UTILITY MODEL FOR EXPANSION AND PROTRACTION OF MAXILLA
Authors: Nasimov El'bek , Aripova Gavkhar , Abdukadirova Nargizakhon , Rasulova Shakhnoza 
Published: February 2023

Subject. Development and application of a new expansion and mesial protraction appliance for maxilla.
Objectives. Determination of required dental arch width and effectiveness of using a new removable appliance for expansion and protraction of maxilla in different age patients.
Methodology. There were 94 patients with narrow and retro positioned maxilla taken for this study and divided for 2 groups: I group – 61 patients at the age of 8–12 years old, II – 33 patients at the age of 13–16 years old to whom complex diagnostic examination including cephalometries and evaluation of required dental arch width with developed “OZDR-RKPFZ.exe” computer program was applied.
Results. A new appliance for expansion and protraction of maxilla was developed at Nasimov Dentistry in cooperation with Department of Orthodontics of TSDI. In 49 (80.32%) patients of the I group 1 mm and more expansion occurred after only 2 weeks of treatment; in 9 (14.75%) of evaluated in 3 weeks and in 3 (4.93%) of evaluated in more than 4 weeks of activation. On the other hand, in 26 (78.78%) of II group skeletal expansion of 1 mm and more occurred in 2 weeks of appliance wearing; in 5 (15.15%) after 3 weeks and in (9.09%) patients after more than 4 weeks of activation. Mesial traction of maxilla using face mask was also effective in short term.
Conclusion. Expansion and protraction in groups by age showed a greater prevalence of progress in transversal and sagittal dimensions in I-group where skeletal maturation was not finished, although activation of appliance was made more and force component was higher. It shows that using of the new appliance in different age is effective if skeletal maturation is taken to account.
CURCUMIN AS A PROMISING PHOTOSENSITIZER FOR PHOTODYNAMIC THERAPY
Authors: Chausskaya Irina , Nikogosova Diana , Drobyshev Alexey 
Published: February 2023

Subject. The tendency of growing antibiotic resistance causes scientific medical community to develop new antimicrobial treatment protocols. Recently, the increased interest in photodynamic therapy has been noted. Photodynamic therapy (PDT) is a non-surgical method of treatment patients with inflammatory diseases and neoplasms in the maxillofacial region, based on the interaction between special light-sensitive chemical compounds — photosensitizers and light radiation. The literature reports the existence of synthetic and natural photosensitizers. Despite the higher stability present by the synthetic photosensitizers, they are more prone to collateral effects. Recently, a growing body of evidence shows the promising applications of curcumin against different diseases, including the pathologies in maxillofacial region. Curcumin is a bioactive compound isolated from the roots of Curcuma longa that has antibacterial, antiviral, anti-inflammatory, and antioxidant properties. The disadvantage of curcumin is that it is unstable at physiological pH, has low water solubility and is rapidly metabolized by the body.
The objective of this work is to review current research aimed at improving curcumin as a photosensitizer used for photodynamic therapy.
Methodology. The analysis of scientific articles from databases of medical and biological publications — scientific electronic library (Elibrary), PubMed and Web of Science, dedicated to the use of curcumin in photodynamic therapy.
Results and conclusion. The results of modern research in the field of laser technologies presented in this review indicate that photodynamic therapy with curcumin, as a photosensitizer is a promising treatment option in many fields of medicine. The aforementioned scientific studies give the understanding that the study and improvement of delivery systems for curcumin photosensitizer by combining it with nanoparticles is a scientific interest.
CLINICAL AND STATISTICAL ANALYSIS OF THE RELATIONSHIP BETWEEN POSTURAL AND NEUROPSYCHIATRIC DISORDERS IN PATIENTS WITH DYSFUNCTIONAL CONDITIONS OF THE TEMPOROMANDIBULAR JOINT
Authors: Martyusheva Marina , Astashina Natal'ya , Shchekolova Natalia , Savchenko Daria , Arutyunov Anatoliy 
Published: February 2023

Diseases of the temporomandibular joint (TMJ), manifested in the form of "dysfunctional disorders", are socially significant and are quite common.
Purpose of the study: to find correlations between postural and neuropsychiatric disorders in patients with dysfunctional disorders of the TMJ to improve diagnosis, treatment and follow-up.
Materials and research methods. In the period from 2015 to 2021, 63 patients with a dysfunctional condition of the temporomandibular joint were examined, including 10 men (15.87%) and 53 women (84.13%) aged 18 to 79 years (average age 43.58). A statistical analysis of the results of the examination of patients with a dysfunctional state of the TMJ was carried out using a visual analogue scale, the Spielberger–Hanin test, the depression scale of the Center for Epidemiological Studies and the Kerdo vegetative index. At the first stage, the results of the questionnaire data, subjective and objective examination were processed, which included an assessment of the function of the dental system, determination of postural status and identification of neuropsychiatric disorders. At the second stage, a correlation analysis was carried out between the results obtained.
Results of own researches. In the course of the study, statistical data on 6 parameters of the Hamburg test were revealed. Correlations were found for the prevalence of nosological forms and pathological changes in the examined patients. The study found patterns of postural and neuropsychiatric disorders.
Conclusion. Based on the correlation analysis, it was proved that postural imbalance has a more pronounced effect on the formation of dysfunctions of the ventricular system than neuropsychiatric disorders. Defects of the dentition, increased wearing of the hard tissues of the teeth and secondary deformities, accompanied by a decrease in the height of the lower part of the face, mutually load each other and distort the clinical picture of TMJ dysfunction at the stage of diagnosis, treatment and follow-up.
ANALYSIS OF THE STRESS-STRAINED STATE IN THE BONE AND THE IMPLANT--BONE INTERFACE DEPENDING ON THE DIAMETER, LENGTH, ANGLE OF THE IMPLANT AND DIRECTION OF APPLICATION OF FORCE
Authors: Saleeva Gul'shat , Grishin Petr , Saleev Rinat , Kalinnikova Elena 
Published: February 2023

Introduction. This article presents the results of mathematical modeling of the stress-strain state in the bone tissue surrounding the implant and the implant-bone connection depending on the diameter and length of the implant in the case of different directions of force application and the implant-bone implant installation angle.
Target. To study the effect of the diameter, length of the implant and the load angle on the stress fields in a three-dimensional implant-bone system with finite elements and determine the effect of the load angle on the stress fields with a change in diameter and length.
Materials and methods. To study the distribution and analysis of the stress-strain state in the bone tissue around implants of different diameters and lengths during dental implantation, a three-dimensional finite element model of the lower jaw was created. Three models were developed using computed tomography and the Universal Surgical Integration System software.
Results. In all cases studied, the maximum stresses were achieved in the cortical bone due to its greater rigidity. However, since cortical and cancellous bone have different strength characteristics, it was necessary to consider the stress in these areas separately.
In the cortical bone, the maximum stresses were always reached near the edge of the hole and the contact with the implant, respectively. In cancellous bone, in many cases, the maximum stresses were noted in the region of the implant apex. At the same time, when the implant is placed at an angle or in the buccolingual direction of load application, the stresses are redistributed in favor of the cancellous bone.
Findings. Thus, in general, it can be concluded that an increase in the length and diameter of the implant leads to a noticeable decrease in stresses in the bone tissue surrounding the implant and in the implant-bone junction. The obtained results demonstrated that implants of small diameter and length, installed in the jawbone at an oblique loading angle, are the least favorable option for stress distribution at the implant-bone interface.
EXPERIMENTAL PARTICIPATION OF PHARMACOLOGICAL SUBSTANCES IN MECHANISMS OF LEAD ACETATE TOXICITY
Authors: Dzugkoev S. G. , Dzugkoeva F. S. , Margieva O. I. , Khubulova A. E. , Mozhaeva I. V. 
Published: February 2023

The aim of the work is to study pharmacological substances that play a role of eNOS expression regulators in the modification of lead intoxication effects in the experiment.Materials and methods. In the experiment, linear male rats of the same age were used: intact and with lead intoxication (120 heads). The study design was the following: group 1 – control; group 2 – intoxication with a lead acetate solution; group 3 – intact + L-nitroarginine methyl ester; group 4 – lead acetate + L-nitroarginine methyl ester; group 5 – intact + L-arginine; group 6 – lead acetate + L-arginine. The research carried out the study state of the redox reactions, the content of nitric oxide (NOx) stable metabolites, a lipid profile, the level of NO-synthase (eNOS) expression in the vascular endothelium, the main processes of urination and the activity of Na+/K+-ATPase in the renal tissue layers, as well as in the liver. The results were subjected to statistical processing.Results. Saturnism caused the oxidative stress development, a decrease in the NOx content in blood plasma, a violation of the L-arginine for eNOS bioavailability, and an endothelial dysfunction. Indicators of the impaired renal function were a decrease in the glomerular filtration rate (GFR), the tubular reabsorption of water, sodium, and the Na+/K+-ATPase activity. The damage to hepatocytes was evidenced by changes in the activity of organ-specific enzymes in the blood and Na+/K+-ATPase. L-arginine exhibited antioxidant properties, increased the NOx content and the level of eNOS expression. The eNOS L-nitroarginine methyl ester inhibitor showed the effects opposite to L-arginine.Conclusion. Biochemical markers of damage to kidney and liver cells during saturnism are indicators of the oxidative stress, NOx deficiency and hemodynamic disturbances in them. These mechanisms involved the following pharmacological substances: an eNOS inhibitor, L-nitroarginine methyl ester, which caused a decrease in the expression level of the enzyme, and an eNOS inducer, L-arginine, which increased this indicator severity. The lead toxicity mechanisms have been implicated in the impaired cholesterol metabolism, contributing to the L-arginine reduced availability for eNOS and the NOx production. Therefore, the use of L-arginine can be recommended as a regulator of the oxidative stress and an NO-producing endothelial function in other pathologies.