bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative Analysis of IOL Power Calculations in Postoperative Refractive Surgery Patients: A Focus on FS-LASIK and SMILE
Authors: Li Liangpin , Yuan Liyun , Yang Kun , Wu Yanan , Hua Xia , Wang Yan , Yuan Xiaoyong 
Published: August 2023

Abstract
Background
As the two most prevalent refractive surgeries in China, there is a substantial number of patients who have undergone Femtosecond Laser-assisted In Situ Keratomileusis (FS-LASIK) and Small Incision Lenticule Extraction (SMILE) procedures. However, there is still limited knowledge regarding the selection of intraocular lens (IOL) power calculation formulas for these patients with a history of FS-LASIK or SMILE.
Methods
A total of 100 eyes from 50 postoperative refractive surgery patients were included in the study, with 25 individuals (50 eyes) having undergone FS-LASIK and 25 individuals (50 eyes) having undergone SMILE. By using a theoretical surgical model, we conducted extensive preoperative and postoperative measurements, including demographic data, corneal biometric parameters, and axial length. Various formulas, including the Barrett Universal II (BUII) formula, as a baseline, were employed to calculate IOL power for the patients.
Results
The Barrett True K (BTK) formula, demonstrated an mean absolute error (AE) within 0.5 D for both FS-LASIK and SMILE groups (0.28 ± 0.25 D and 0.36 ± 0.24 D, respectively). Notably, the FS-LASIK group showed 82% of results differing by less than 0.25 D compared to preoperative BUII results. The Barrett True K No History (BTKNH) formula, which also incorporates measured posterior corneal curvature, performed similarly to BTK in both groups. Additionally, the Masket formula, relying on refractive changes based on empirical experience, displayed promising potential for IOL calculations in SMILE patients compared with BTK (p = 0.411).
Conclusion
The study reveals the accuracy and stability of the BTK and BTKNH formulas for IOL power calculations in myopic FS-LASIK/SMILE patients. Moreover, the Masket formula shows encouraging results in SMILE patients. These findings contribute to enhancing the predictability and success of IOL power calculations in patients with a history of refractive surgery, providing valuable insights for clinical practice. Further research and larger sample sizes are warranted to validate and optimize the identified formulas for better patient outcomes.
Systemic lupus erythematosus promotes HCC by promoting cell cycle C2/M transition
Authors: Zhang Xusheng , Zhou Hongcai , Wei Peng , Ma Weihu , Liu Kejun , Chen Bendong 
Published: August 2023

Abstract
Objective
To investigate whether there is an association between immune abnormalities and hepatocellular carcinogenesis in patients with the autoimmune disease systemic lupus erythematosus (SLE), and to explore the possible mechanisms of the association.
Methods
Based on the mRNA-Seq data of SLE and hepatocellular carcinoma in the public database, we screened the differentially expressed genes using GEO2R, R "Limm" package, and weighted gene co-expression network analysis (WGCNA), respectively, and used random forest tree algorithm to screen out the common genes in both diseases. A random forest(RF) tree algorithm was used to screen out the common genes in the two diseases, to investigate the biological functions of the genes in hepatocellular carcinoma, to construct a nomogram risk prediction model for hepatocellular carcinoma, and to evaluate the predictive efficiency of the model. The immune profile in hepatocellular carcinoma was evaluated based on CIBERSORT and ssGSEA algorithms, and the association of signature genes with the level of tumor immune cell infiltration and the correlation of immune checkpoints in hepatocellular carcinoma were also explored.
Results
The expression levels of 2 SLE signature genes, CCNB2 and TOP2A, were significantly upregulated in hepatocellular carcinoma, and showed good diagnostic efficacy and clinical prognostic efficacy for hepatocellular carcinoma, suggesting that they may be potential biological targets for hepatocellular carcinoma, and the hepatocellular carcinoma risk prediction model based on the expression levels of CCNB2 and TOP2A showed good risk prediction for hepatocellular carcinoma and has good potential for clinical application. In addition, it was found that the up-regulation of CCNB2 expression may accelerate the G2/M transition of the hepatocellular carcinoma cell cycle, inhibit the apoptotic process, and promote the rate of tumor cell appreciation through the mediation of the p53 signaling pathway, thus contributing to the development and progression of hepatocellular carcinoma.
Conclusion
The SLE signature genes CCNB2 and TOP2A are potential predictive targets for new-onset hepatocellular carcinoma in SLE patients, and the upregulation of CCNB2 expression may promote hepatocellular carcinoma development and progression through the mediation of the p53 signaling pathway.
Combining temperature-dependent life table data into Insect Life Cycle Model to forecast fall armyworm Spodoptera frugiperda (JE Smith) distribution in maize agro- ecological zones in Africa
Authors: Adan Marian , Tonnang Henri E.Z. , Kassa Cojdo E.F. , Greve Klaus , Borgemeister Christian , Goergen Georg 
Published: August 2023

Abstract

The fall armyworm (FAW) Spodoptera frugiperda (JE Smith) (Lepidoptera: Noctuidae), is an agricultural pest that recently invaded Africa. FAW has spread and established in many countries across the continent, causing huge yield losses. This study aimed to determine the relationship between temperature and the life history traits of FAW and to provide the suitable temperatures for development using life cycle modeling. Non-linear models were fitted to life table data collected at five constant temperatures of 20, 25, 28, 30, and 32 °C. The development time ranged between 0–3 days, 10–18 days, and 7–16 days for eggs, larvae, and pupae, respectively. While the optimum temperature for FAW immature stages' survival and female fecundity was predicted at a temperature range of 21–25 °C, the intrinsic rate of increase (rm) and gross reproductive rate (GRR) were significantly higher at temperatures between 25–28 °C. The model validation outcome showed similarities between observed and simulated values for development time, mortality rate, and life table parameters, attesting to the high performance of the phenology model produced. The study also explores the establishment risk index, activity index, and generation index as indicators of infestation and transmission potential of the current, 2050, 2070 climate scenarios to predict the effect of climate warming on the distribution and population dynamics of FAW. The study predicts a decrease in FAW occurrence in West Africa by 2050–2070. The results obtained could be utilized to develop management plans for FAW control that work in the different agro-ecological zones in Africa.
Improving Physical Movement During Stroke Rehabilitation: Investigating Associations Between Sleep Measured by Wearable Actigraphy Technology, Fatigue, and Key Biomarkers
Authors: Smith Madeleine J. , Pellegrini Michael , Major Brendan , Graco Marnie , Porter Stephanie , Kramer Sharon , Sewell Katherine , Salberg Sabrina , Chen Zhibin , Mychasiuk Richelle , Lannin Natasha A. 
Published: August 2023

Abstract
Background
Sleep disturbances and fatigue are common in individuals undergoing inpatient rehabilitation following stroke. Understanding the relationships between sleep, fatigue, motor performance, and key biomarkers of inflammation and neuroplasticity could provide valuable insight into stroke recovery, possibly leading to personalized rehabilitation strategies. This study aimed to investigate the influence of sleep quality on stroke recovery by utilizing wearable technology to obtain objective sleep measurements. Additionally, we explored the relationships between sleep, fatigue, and motor performance. Lastly, the study aimed to determine if salivary biomarkers of stress, inflammation, and neuroplasticity were associated with fatigue or motor function post-stroke.
Methods
Eighteen individuals who experienced a stroke and were undergoing inpatient rehabilitation participated in a cross-sectional observational study. Following consent, participants completed questionnaires to assess sleep patterns, fatigue, and quality of life. Objective sleep was measured throughout one night using the wearable Philips Actiwatch. Upper limb motor performance was assessed on the following day and saliva was collected for biomarker analysis. Correlation analyses were performed to assess the relationships between variables.
Results
Participants reported poor sleep quality, frequent awakenings, and difficulties falling asleep following stroke. We identified a significant negative relationship between fatigue severity and both sleep quality (r=-0.539, p = 0.021) and participants experience of awakening from sleep (r=-0.656, p = 0.003). A significant positive relationship was found between grip strength on the non-hemiplegic limb and salivary gene expression of Brain-derived Neurotrophic Factor (r = 0.606, p = 0.028), as well as a significant negative relationship between grip strength on the hemiplegic side and salivary gene expression of C-reactive Protein (r=-0.556, p = 0.048). Additionally, there was a positive relationship between gene expression of Interleukin-1beta and stroke severity (r = 0.78, p = 0.003) as well as between days since stroke and gene expression of C-reactive Protein (r = 0.615, p = 0.025).
Conclusion
The findings of this study emphasize the importance of considering sleep quality, fatigue, and biomarkers in stroke rehabilitation to optimize recovery and that interventions may need to be tailored to the individual. Future longitudinal studies are required to explore these relationships over time. Integrating wearable technology for sleep monitoring and biomarker analysis can enhance monitoring and prediction of outcomes following stroke, ultimately improving rehabilitation strategies and patient outcomes.
Research on Gear Profile Deviation Detection Method Based on Linear structured light
Authors: Jiang Xin , Zhang Xianglei , Lu Wangda , Zhou Hongming 
Published: August 2023

Abstract
Gear requires a reliable, holistic, and rapid inspection method to ensure manufacturing accuracy. Linear structured light provides a fast and effective solution to meet the rapid testing requirements of gear manufacturers. But its accuracy still needs to be improved. This method can obtain 33000 3D data points of a single gear tooth surface in less than 0.3 seconds. And based on this, evaluate the tooth profile error of the gear. The results indicate that the measurement deviation amount to 1.47µm in measuring gears of level 7 accuracy compared to the gear measurement center. The error mainly comes from the equipment error and the down-sampling process using centroid method. In the measurement process, the larger the deviation between the contact position of the gear and the light and the focus position of the linear structured light, the greater the error. The larger the neighborhood search radius during the calculation process, the larger the error.
EKV Model Base Analog/RF CMOS DesignPre-SPICE Tool
Authors: Khademevatan Gholamreza , Jalali Ali 
Published: August 2023

Abstract
A novel simplified EKV model base analog/RF CMOS design pre-SPICE tool is presented in this paper. Addition to facilitating the sizing process, this CAD tool can also optimize circuit characteristics. By having a web address, users can access it without installing any software. Usinga graphical and a numerical view, the designer can select degrees of freedom and observe the MOS circuit performance. Through the use of charts versus IC, the graphical view can show tradeoffs in circuit performance in real time. Charts can be displayed simultaneously in both linear and logarithmic scales. ICcrit, is also available and can be displayed on the charts. This tool is not limited to one process and it is possible to select different processes. A methodology for selecting optimum ICsis presented by this tool. It is illustrated through the study of linearity indices, AIP3 and IIP3, in one-stage and two-stage differential amplifiers.
Investigating the Potential of PerovskiteNanocrystal-Doped Liquid Scintillator: A FeasibilityStudy
Authors: Kim Na-Ri , Joo Kyung-Kwang , Lee Hyun-Gi 
Published: August 2023

Abstract
Liquid scintillators are extensively employed as targets in neutrino experiments and in medical radiography. Perovskitenanocrystals are recognized for their tunable emission spectra and high photoluminescence quantum yields. In this study, weinvestigated the feasibility of using perovskites as an alternative to fluor, a substance that shifts the wavelengths. The liquidscintillator candidates were synthesized by doping 450, 480 and 510-nm perovskite nanocrystals into fluor PPO with varyingnanocrystal concentrations in a toluene solvent. The several properties of the perovskite nanocrystal-doped liquid scintillatorwere measured and compared with those of a secondary wavelength shifter, bis-MSB. The emission spectra of the perovskitenanocrystal-doped liquid scintillator exhibited a distinct monochromatic wavelength, indicating energy transfer from PPO to theperovskite nanocrystals. The light yield, pulse shape, and wavelength shift of the scintillation events were measured basedon the Compton scattering of a 60Co radioactive source, triggered by a coincidence of photomultiplier tube (PMT). The lightyields were evaluated from observed Compton edges from the g - ray source. A decrease (or increase) in area-normalized PMTpulse height was observed at higher perovskite nanocrystal (or PPO) concentrations. The results demonstrated the sufficientpotential of perovskite nanocrystals as an alternative to traditional wavelength shifters in liquid scintillator.
Lisfranc fracture-dislocation treated with a nickel-titanium shape memory alloy nail angle fixator: A retrospective case study
Authors: Bu Pengfei , Ma Xinyu , Li Chuan , Qi Baochuang , Pu Luqiao , Xu Yongqing 
Published: August 2023

Abstract
BACKGROUND:To investigate the clinical efficacy of a nickel-titanium (Ni-Ti) memory alloy nail angle fixator in the treatment of Lisfranc fracture-dislocation.
METHODS: A retrospective case study was carried out to analyze the clinical data of seven patients (4 male; 3 female) aged 23–60 years [(44 ± 12.5) years] with Lisfranc fracture-dislocation admitted to the 920 Hospital of the People's Liberation Army Joint Logistic Support Force between November 2018 and April 2022. All injuries were fresh and closed and there were 3 cases observed in the left foot and 4 in the right foot. The Myerson classification of the fractures showed: 1 case of type A, 2 cases of type B1, 3 cases of type B2, and 1 case of type C1. Open reduction and internal fixation were performed using a Ni-Ti shape memory alloy nail angle fixator. The affected feet were observed for complications and fracture-dislocation healing. Foot function was assessed using the Visual Analogue Score for pain (VAS) and the American Orthopedic Foot and Ankle Society (AOFAS) Midfoot Scale.
RESULTS: Patients were followed-up for 9–48 months, with a mean follow-up period of 18.9 months. One Myerson A patient had a broken Lisfranc screw that was used to remove the internal fixation, however, the broken part was not removed. There were no other abnormalities in the remaining patients. Radiography indicated normal longitudinal arch morphology and good anatomical alignment of the foot joints in all seven patients. At the final follow-up, VAS scores ranged from 0–3 with a mean of 1.7, and AOFAS scores ranged from 85–97 with a mean of 90.6. There were 5 cases of excellent healing and 2 cases of good healing, with a satisfactory rating of 100%.
CONCLUSION: The procedure of using a Ni-Ti shape memory alloy nail angle fixator to treat Lisfranc fracture-dislocation is relatively simple with good fixation of the fracture-dislocation, satisfactory postoperative functional recovery of the foot, effective pain relief, and few surgical complications, thereby offering a novel option for clinical treatment.
Impact of Climate Change on Rainfall Patterns in the Yeh Embang Watershed
Authors: Eryani I Gusti Agung Putu , Jayantari Made Widya , Amir Amnorzahira 
Published: August 2023

Abstract

Climate change directly impacts rainfall trends in many parts of the world. This research aimed to analyze the impact of climate change on rainfall patterns in the Yeh Embang watershed by examining the changes in rainfall patterns in the Yeh Embang watershed. This analysis can be used as a guide when determining how to manage water resources sustainably in the watershed. Changes in rainfall patterns are analyzed, and the relationship with climate change is seen after they are classified into three periods. According to the analysis, it can be seen that climate change occurred from 2005–2009 to 2010–2014 and from 2010–2014 to 2015–2019. In the last five years, there has been an increase in rainfall, temperature, and wind speed. With increased rainfall, temperature, and wind speed, there is a potential for increased hydrological hazards, such as flooding during the rainy season and drought during the dry season.
Singular disposition of the posterior cross vein in a wing venation network
Authors: Sugiyama Kazuki , Kubota Yoshihiro , Mochizuki Osamu 
Published: August 2023

Abstract
We investigated the network topology of the wing veins of fruit flies and observed that the posterior cross vein disrupted the symmetry of the entire network. The purpose of this vein has remained unknown, notwithstanding prior study of its development and its positional variety among different species. We examined the vein's effect on hydration dynamics in the wing membrane and on the internal blood flow of the venous system, applying computational removal or repositioning of the vein rather than physical manipulation. We determined the balance of flow velocities between the water supply from the veins to the wing membrane and the evaporation from the membrane. The position of the posterior cross vein maximises the ratio of the supply flow velocity to the evaporative velocity in the adjacent membrane, with supply occurring more than seventy times faster than evaporation. We found that this vein’s position minimises the pressure loss accompanying blood flow through the vein, using iterative calculations to derive the flow distribution that satisfies pressure balances at bifurcations in the venous network. This particular vein's location exhibited the greatest reduction in pressure loss throughout the entire vein network. Our results highlight the topological adjustments in wing venation that influence circulation.
The comparison of flow rate calibration methods for high performance liquid chromatography (HPLC) pump
Authors: Uthaiwat Prangtip , Leeudomwong Theera , Sanponpute Tassanai 
Published: August 2023

Abstract
High performance liquid chromatography (HPLC) pump has a main function to deliver a mobile phase which need accuracy and stable flow rate. Recently, three flow rate calibration methods are used to test the HPLC pump performance such as using standard flow meter, gravimetric method, and volumetric method. These calibration methods have not been clearly described. Therefore, this study aimed to investigate and compare the flow rate calibration by the using of standard flow meter, gravimetric method, and volumetric method. The flow rate was calibrated at 0.5 and 5 mL/min with 3 replications. The stability between day of each method was observed for 3 days. The calibration procedure, traceability chart, and uncertainty budget of each method had been described. The flow rate results were analyzed by using the En ratio. The results showed that the stability of all methods had no statistically significant difference between day when compared to the first day of itself. The measurement flow rates by the using standard flow meter, gravimetric method, and volumetric method at 0.5 mL/min were 0.5062, 0.4992, and 0.5012 mL/min, respectively and at 5 mL/min were 4.9172, 4.8272, and 4.8394 mL/min, respectively. These flow rates showed consistent results between each other as confirmed with the En ratio ≤ 1. The precision of the three methods was 0.01–0.08%RSD. This study concluded that the flow rate results of three calibration methods had consistent with each other. All methods had a good stability and precision for the flow rate calibration of the HPLC pump.
Schrödinger-Maxwell equations driven by mixed local-nonlocal operators
Authors: Cangiotti Nicolò , Caponi Maicol , Maione Alberto , Vitillaro Enzo 
Published: August 2023

Abstract

In this paper we prove existence of solutions to Schrödinger-Maxwell type systems involving mixed local-nonlocal operators. Two different models are considered: classical Schrödinger-Maxwell equations and Schrödinger-Maxwell equations with a coercive potential, and the main novelty is that the nonlocal part of the operator is allowed to be nonpositive definite according to a real parameter. We then provide a range of parameter values to ensure the existence of solitary standing waves, obtained as Mountain Pass critical points for the associated energy functionals.
METTL3 mediated m6A methylation of HIF-1 α promoted progression in glioma
Authors: Wang Jubo , Ren Pengyu , Quan Yu , Jian Lv 
Published: August 2023

Abstract
Background
Glioma was a malignant tumor of the central nervous system. m6A methylation and HIF-1α were related to the occurrence and development of gliomas. However, the co-mechanism of m6A methylation and HIF-1α in glioma is unclear.
Objective
This aim was to determine the m6A methylation of HIF-1α in glioma.
Methods
Elisa and dot blot were used to detect m6A level. The changes of related genes, biological pathways and gene ontology were analyzed by bioinformatics. METTL3 and HIF-1α were knockdown by sh-RNA, and the mRNA and protein level were detected by qPCR and western blot. In addition, the m6A RNA methylation sites were predicted and verified by m6A-RIP-MMP-6 analysis༎
Results
We found that compared with paracancerous, the mRNA and protein levels of m6A were dramatically increased in glioma. The biological different were found in glioma and paracancerous. Moreover, glioma had highly mRNA and protein level of HIF-1α. METTL3 and HIF- 1α knockdown can significantly decrease the growth of glioma cells. Furthermore, we confirmed the m6A RNA methylation site in HIF-1α. Finally, we found that METTL3 regulated the m6A level and RNA stability of HIF-1α.
Conclusion
Our finding demonstrated that the co-mechanism of m6A methylation of HIF-1α and METTL3 in glioma, and may be helpful in the treatment of glioma.
Comparative Analysis of Deep Learning Based Steel Surface Defect Detection under Different Lighting Conditions
Authors: AKIN ERHAN , AYDIN Ahmet , AYDIN İlhan 
Published: August 2023

Abstract
The automatic inspection and detection of defects on flat steel surfaces is important for product manufacturers as well as for users of these products. Since industrial products are used in various fields such as transportation, energy production, food production, the inspection of these products is a difficult problem today. Traditional methods such as image processing or machine learning used to provide inspections give successful results in detecting sufficiently illuminated, strong contrast or obvious defects. In this study, flat steel surface defects, which is an industrial product, are discussed. The aim of the study is to test the robustness of deep learning methods under different illumination conditions and to determine their response. For this purpose, four popular YOLO object detection methods are used. Because of the different illuminations applied on the data set, the changes in the defect detection algorithms have been observed and the results are shared. Experimental results clearly demonstrate the effect of lighting on model success. In addition, the proposed approach presents an improvement in terms of both detection rate and frame rate compared to studies in the literature.