bluuebunny/crossref_metadata_2025_split huggingface dataset:
Causal effects of education attainment on oral and oropharyngeal cancer: New evidence from a meta-analysis and Mendelian randomization study
Authors: Chen Gui , Xie Junyang , Liu Di , Zhang Xiaowen , Tang Anzhou 
Published: April 2023

ObjectivesHigher educational attainment (EA) has proven to be beneficial for preventing and treating various types of cancers. Currently, there is little evidence on the association between EA and prevention of oral cavity and pharyngeal cancer (OCPC).MethodsSeveral databases were searched until October 1, 2022, and a meta-analysis was performed. A Mendelian randomization (MR) study was conducted with EA (i.e., the exposure) data derived from the Social Science Genetic Association Consortium and 6,034 cases of OCPC (i.e., outcome) selected from the Integrative Epidemiology Unit genome-wide association study. Five methods were used to evaluate the causality between EA and OCPC. The leave-one-out sensitivity test, MR-Egger regression, and multivariable MR (MVMR) analysis were applied to evaluate the MR results.ResultsThe meta-analysis included 36 eligible studies. EA was significantly and negatively associated with OCPC risk (odds ratio [OR]: 0.439, 95% confidence interval [CI]: 0.383–0.503, P &lt; 0.001). MR analysis revealed that the risk of OCPC, oropharyngeal cancer, and oral cavity cancer decreased with an increase in education (OR: 0.349, 95% CI: 0.222–0.548, P &lt; 0.001; OR: 0.343, 95% CI: 0.198–0.597; P &lt; 0.001; OR: 0.342, 95% CI: 0.195–0.601, P &lt; 0.001, respectively). Even after correcting for mediators, high EA still significantly reduced the risk of OCPC (OR: 0.361, 95% CI: 0.281–0.463, P &lt; 0.001).ConclusionBoth the meta-analysis and MR results demonstrated that high levels of EA can reduce the risk of OCPC in the general population.
Impact of pulsed electric fields (PEF) treatment on the peeling ability of tomatoes and kiwi fruits
Authors: Giancaterino Marianna , Jaeger Henry 
Published: April 2023

Peeling is a standard food processing operation that removes the outer layer of fruits and vegetables. It can improve the appearance and texture of many fruits and vegetables and is often necessary for further food preparation. Developing new and innovative peeling methods to minimise losses and enhance product quality is an area of active research in the food industry. The objective of this study was to evaluate how PEF affects the peeling ability of tomatoes and kiwi fruits, as well as the chemical and physical characteristics of the resulting peeled products. In detail, monopolar exponential decay pulses were applied, with an electric field strength of 1.0 kV/cm and a resulting total energy input in the range of 0.6 and 5.0 kJ/kg for tomatoes and 1.2 and 12.6 kJ/kg for kiwi fruits. Two methods were used to compare the effectiveness of PEF treatments with traditional peeling methods: hot-water blanching (98°C for 60 s) and lye peeling (98°C for 45 s, in 2% NaOH solution). The peeling efficiency was evaluated through manual and mechanical methods as well as measuring weight loss. The quality of the final peeled product was assessed by mechanical properties of the pericarp, colour (L*, a*, b* scale), ascorbic acid content, chlorophyll a and b, carotenoids, total polyphenols content and antioxidant activity. The PEF treatment applied to whole red tomatoes (1.0 kV/cm, 5.0 kJ/kg) and whole kiwi fruits (1.0 kV/cm, 12.6 kJ/kg) resulted in a significant decrease (p≤ 0.05) of up to 43% and 83% in the force required for mechanical peeling, respectively. The PEF treatment showed comparable or superior peeling ability and significantly reduced product losses compared to hot-water blanching and lye peeling methods. However, the softening and the weight losses tend to increase by increasing the pulses for both investigated matrices. Moreover, by applying PEF instead of blanching or lye peeling, the chemical quality and the colour were better preserved (ΔE &lt; 2). This study proved that PEF could be a promising non-thermal technology to better peel tomatoes and kiwi fruits without affecting their final quality. Consequently, applying PEF as a treatment to facilitate peeling has remarkable potential as an industrial application to reduce energy consumption and issues related to wastewater management typically occurring during the peeling with lye agents.
Combination of conservative and surgical methods in the treatment of giant lymphedema of the scrotum: A case report
Authors: Istranov Andrey L. , Makarov Ivan G. , Makarova Natalya V. , Tulina Inna , Ulasov Ilya V. , Isakova Yuliya I. 
Published: April 2023

ObjectiveGenital lymphedema is a severe, disabling condition associated with a malfunction of the lymphatic system. Primary lymphedema of the scrotum is a variant of congenital dysplasia of lymphatic vessels. Secondary genital lymphedema is much more common and can be caused by parasitic invasion (filariasis) or damage to the lymphatic system during the treatment of cancer (radiation therapy, lymphadenectomy). Healthcare providers are frequently unable to detect and treat this illness successfully in ordinary clinical practice. This paper uses the case of a patient with stage 3 secondary lymphedema (unknown genesis) of both lower extremities and lymphedema of the scrotum, complicated by recurrent erysipelas, a history of lymphorrhoea, impaired skin trophic and multiple papillomatosis, to demonstrate the efficacy of a combination of conservative and surgical methods in the treatment of giant lymphedema of the scrotum.MethodsIn the treatment, the combination of decongestant physical therapy (CDPT, CDT) according to M. Földi was used at pre-surgery and post-surgery stages, combined with a reconstructive operation, including the removal of the affected tissues of the urogenital region, phalloplasty, and scrotoplasty with rotational skin flaps.ResultsA decrease in the circumference of the lowest extremities in the lower leg area by 68 cm on the right and by 69 cm on the left was achieved by conservative treatment. Due to the combination of conservative and surgical treatment, the patient's body weight decreased by 69.4 kg, and the scrotum decreased by 63 cm. Subsequently, the patient fully recovered his sexual function.ConclusionA combination of complex decongestive physical therapy and surgery is necessary for patients with advanced genital edema. The isolated use of surgical or conservative treatment does not provide a sufficient improvement in the patient's quality of life. Modern plastic surgery technologies enable patients to achieve complete functional and cosmetic recovery, while proper selection and usage of compression hosiery help preserve and improve the outcomes acquired following treatment.
Tropilaelaps mercedesae Infestation Is Correlated with Injury Numbers on the Brood and the Population Size of Honey Bee Apis mellifera
Authors: Ling Tial C. , Phokasem Patcharin , Sinpoo Chainarong , Chantawannakul Panuwan , Khongphinitbunjong Kitiphong , Disayathanoowat Terd 
Published: April 2023

Tropilaelaps mercedesae, one of the most devastating parasitic mites of honey bee Apis mellifera hosts, is a major threat to honey products by causing severe damage to honey bee colonies. Here, we recorded injury numbers caused by T. mercedesae to different body parts of the larval, pupal, and crippled adult stages of honey bee A. mellifera. We evaluated the relationship between infestation rate and injury numbers per bee for both larvae and pupae. We also noted the total bee numbers per beehive and examined the relationship between the infestation rate and population size. T. mercedesae infested all developmental stages of honey bees, with the highest injury numbers in the abdomens of bee pupae and the antennas of crippled adult bees. Although larvae received more injury numbers than pupae, both infestation rate and injury numbers decreased as the larval stage progressed to the pupal stage. The infestation rate increased as the population size per beehive decreased. This study provided new perspectives to the understanding of changes in the effects of T. mercedesae infestations on different developmental stages of honey bees. It also showed useful baseline information for screening honey bee stock that might have high defensive behaviors against mite infestation.
STATUS SOSIAL EKONOMI DAN PERAN TENAGA KESEHATAN TERHADAP KUNJUNGAN ANTENATAL CARE MASA PANDEMI COVID-19 DI BPM HENI AFRINA KOTA PEKANBARU TAHUN 2021
Authors: NINGSIH Tengku 
Published: April 2023

Pendahuluan: Saat ini, Indonesia sedang menghadapi bencana nasional non alam COVID-19 sehingga pelayanan kesehatan maternal dan neonatal menjadi salah satu layanan yang terkena dampak baik secara akses maupun kualitas, banyak pembatasan hampir ke semua layanan rutin termasuk pelayanan kesehatan maternal dan neonatal. Seperti ibu hamil menjadi enggan ke Puskesmas atau fasiltas pelayanan kesehatan lainnya karena takut tertular. Ada beberapa faktor menjadi penyebab ibu hamil kurang patuh dalam melakukan ANC secara teratur dan tepat waktu, antara lain: kurangnya pengetahuan ibu hamil tentang ANC, kesibukan, tingkat sosial ekonomi yang rendah, dukungan suami yang kurang, kurangnya kemudahan untuk pelayanan maternal, asuhan medik kurang baik, kurang tenaga terlatih dan obat penyelamat jiwa. Tujuan: untuk mengetahui hubungan status sosial ekonomi dan peran tenaga kesehatan tehadap kunjungan ante natal care pada masa pandemi Covid-19. Metode: Penelitian kuantitatif dengan studi korelasi (correlation study). Populasi dan sampel ibu hamil yang datang memeriksakan kehamilan di BPM Henni Afrina Kota Pekanbaru bulan Desember 2021 sebanyak 31 responden. Pengambilan sampel menggunakan total sampling. Instrumen yang digunakan kuesioner, menggunakan uji statistik Chi Square p˂0,05 data diolah menggunakan SPSS. Hasil: Analisa uji Chi Square peran tenaga kesehatan nilai p value sebesar 1,000 dan status sosial ekonomi p value 0,810. Kesimpulan: Tidak ada hubungan yang signifikan antara peran tenaga kesehatan dan status sosial ekonomi terhadap kunjungan ante natal care, diharapkan kepada petugas kesehatan meningkatkan penyuluhan, meningkatkan kegiatan konseling dan promosi secara kontinu dengan ilmu ter-update serta pengembangan multimedia dalam penyampaian materi.
Analisis Kemampuan Literasi Numerasi Pada Siswa Kelas IV Di SD Negeri Tlogosari 01 Semarang
Authors: Anita Dian Pratiwi  , Aryo Andri Nugroho  , Rina Dwi Setyawati  , Susilo Raharjo  
Published: April 2023

The culture of literacy in Indonesia is so low, the factor that affects the low literacy in Indonesia is the lack of interest in reading in Indonesian society. Literacy itself can be related to skills in certain fields. Literacy that is closely related to the ability to think critically is numeracy literacy. Numeracy literacy is closely related to mathematics so that numeracy literacy is the ability to reason using language and mathematics. This research uses descriptive qualitative research. The purpose of this research is to analyze the numeracy literacy skills of grade IV students. The subject of this research involved 6 fourth grade students at SDN Tlogosari Kulon 01 Semarang. The research instruments used were interviews and worksheets in the form of student math story problems to analyze students' numeracy literacy skills. Based on the results of research from 6 students who worked on worksheets in the form of math story problems, there was one student who had low-level numeracy literacy skills, 3 people had medium-level numeracy literacy skills, and 2 students had high-level numeracy literacy skills. So it can be concluded that the numeracy literacy skills of fourth grade students at SDN Tlogosari Kulon 01 Semarang are at a moderate level.

Budaya literasi di Indonesia termasuk rendah, faktor yang mempengaruhi rendahnya literasi di Indonesia adalah kurang minat baca pada masyarakat Indonesia. Literasi sendiri dapat dihubungkan dengan keterampilan di bidang terntu. Literasi yang berkaitan erat dengan kemampuan dalam berpikir kritis adalah literasi numerasi. Literasi numerasi berkaitan erat dengan matematika sehingga literasi numerasi adalah kemampuan bernalar menggunakan bahasa dan matematika. Penelitian ini menggunakan penelitian kualitatif jenis deskriptif. Tujuan penelitian dilakukan penelitian ini adalah untuk menganalisis kemampuan literasi numerasi siswa kelas IV. Subjek penelitian ini melibatkan 6 siswa kelas IV di SDN Tlogosari Kulon 01 Semarang. Instrumen penelitian yang digunakan adalah wawancara dan hasil lembar kerja berupa soal cerita matematika siswa untuk menganalisis kemampuan literasi numerasi siswa. Berdasarkan hasil penelitian dari 6 siswa yang mengerjakan lembar kerja berupa soal cerita matematika terdapat satu siswa memiliki kemampuan literasi numerasi tingkat rendah, 3 orang memiliki kemampuan literasi numerasi tingkat sedang, dan 2 siswa memiliki kemampuan literasi numerasi tingkat tinggi. Sehingga dapat simpulkan bahwa kemampuan literasi numerasi siswa kelas IV di SDN Tlogosari Kulon 01 Semarang berada ditingkat sedang.
Linguotoxic Processes in the Modern German Language
Authors: Trishina Maria 
Published: April 2023

The article substantiates the relevance of the study of linguotoxins as integral components of communication. The study is carried out on the example of the German language world picture, and such linguotoxic processes as unjustified
borrowings, label formation, vulgarization of language / speech, etc. are considered. The study of the corresponding problem field suggests that the phenomena of toxic communication in the German language are widespread. A number of extralinguistic factors, which include, for example, the migration crisis, gender
discrimination, the active expansion of foreign constructions into the German language, etc., have an impact on the speech of native speakers, and, consequently,on the integral construct of the language. The social significance and interdisciplinary nature of this problem require an integrated linguistic approach to its
study and description in order to improve the communicative level of native speakers and reduce verbal aggression, social tension, and ensure the purity and health of the language.
The Empire in the Political Strategy of Order States of Prussia and Livonia on the Turn of the 15th – 16th Centuries
Authors: Bessudnova Marina 
Published: April 2023

The implementation of an imperial project to include the Order states of Prussia and Livonia into the Holy Roman Empire as princedoms didn’t meet interests of the Supreme and Livonian Masters of the Teutonic Order. Wishing to keep the status of sovereign rulers, they intended to maintain traditional relations
with the emperor as the «defender» of the Order, from whom they expected some help to resolve foreign policy problems of the Prussian and Livonian branches of the Order in their confrontation with the Polish-Lithuanian Jagiellonowie and the
Moscow state. The masters were slow over accepting the ducal regalia and transfer their possessions into the rank of imperial fiefs until they had hope for help from the second «curator» of the Order states, the pontificate, on which the order’s privileges preservation and the receipt of cash grants by the Order within
«papal grace» (cruciate) also depended. The low efficiency of such analysis and the beginning of the Reformation made inevitable the final course of the Order states for rapprochement with the empire.
About the Poetics of Sergey Rafalsky
Authors: Semina Anna 
Published: April 2023

In the article the author proves that the habit of researching the poetry by Sergey Rafalsky in the traditions of the Prague group «Skete of Poets» needs revising, because the poet emphasized his disagreements with the creative practice of that group and its leader A. Bem repeatedly. The author identifies some features, that indicate how the artistic credo of the «Paris note» influenced the poetics by Rafalsky, and notices the specificity, that allows us to speak about Rafalsky’s succession to G. Ivanov and G. Adamovich. The author analyses the poems, in which Rafalsky demonstrates implicitly his solidarity with the criteria
of the genuine poetry in G. Adamovich’s comprehension and attempts to reconstruct intonations of conversational natural speech as adequately as possible, with its fragmentariness, understatement and incomplete information. All these
features were intrinsic to the poets of the «Paris note». The author proves that the poems of Rafalsky’s late period ought to be analysed in the context of the creative quests of the poets of Russian Montparnasse, although the influence of the avantgarde poetics is still strong in them. One of the reasons of such esemblance is an intonation dominant of the poetry of Rafalsky, who makes the most of Lermontov's and Blok's legacy in this aspect. Both of these poets were the gold standard for
the poets of the «Paris note», as well as G. Ivanov
Correlation of Serum Vitamin D Levels with the Severity of Diabetic Foot Ulcers in Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia
Authors: Gunawan Vidro Alif , Kemas Muhammad Dahlan  , Legiran  
Published: April 2023

Background: Vitamin D has a role in diabetes mellitus. Low levels of vitamin D are associated with the development of diabetic foot infections. Effects of vitamin D supplementation on wound healing, insulin resistance, inflammatory biomarkers, and oxidative stress are mediated by effects on induction of phagocytosis and bacterial killing by macrophages, suppression of interferon-gamma mediating macrophage activation, activation of insulin receptor expression, and downregulation from cytokines. This study aimed to determine the correlation between serum vitamin D levels and the severity of diabetic foot ulcers in Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia.
Methods: This study was an observational analytics study, where as many as 30 research subjects participated in this study. The study observed vitamin D levels and the severity of diabetic foot ulcers as assessed by the classification of the wound, ischemia, and foot infection (WIfI). Univariate and bivariate data analysis was carried out using SPSS.
Results: The results of Sommer's correlation statistical test obtained a value of p = 0.001 (p <0.05) with a correlation strength of r = 0.564, which means sufficient strength (r = 0.40-0.70). This means that the higher the deficiency in serum Vitamin D levels, the higher the degree of WIfI classification experienced.
Conclusion: There is a correlation between serum vitamin D levels and the severity of diabetic foot ulcers in Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia.
Creencias Cognitivas Distorsionadas y los Efectos de la Psicoterapia Cognitiva Conductual en dos Casos de Mujeres con Trastorno Límite de la Personalidad
Authors:   , Robles Mariela 
Published: April 2023

Esta investigación ha sido presentada, para obtener el título de Doctora en Psicología Clínica; por la Universidad Santa María La Antigua. Durante los años 2006 y 2008 realice la Práctica Clínica en el Centro Femenino de Rehabilitación (CFR), de allí nace la idea de efectuar el trabajo de tesis, con internas diagnosticadas, con un trastorno límite de la personalidad. El trastorno límite de la personalidad (TLP) es uno de los trastornos que más discusión causa; la combinación de los síntomas clínicos, su dificultad para conceptualizarlo; así como de una teoría que logre unificar los diversos planteamientos entre autores, han desembocado en desacuerdos y tratamientos que son eficaces para tratar algunos síntomas, pero deja por fuera otros síntomas que también deben ser tratados.	Este trabajo se enfoca en explicar, cómo son las creencias cognitivas en dos internas (estudio de casos) con trastorno límite de la personalidad y su intervención desde el modelo cognitivo conductual; con la finalidad de mejorar su padecimiento, con el fin de que puedan llevar sus vidas de manera más funcionales.	Esta tesis se presenta en cuatro capítulos. Además de los resultados del trabajo planteado en las conclusiones y los hallazgos, se exponen las respuestas a las preguntas de investigación.
Flexible Objektdetektion in 3D-Lidar-Scans/Flexible object detection in 3D lidar scans – Development of an object recognition system for creating and updating digital models
Authors: Willenbrink Matthias , Karelina Dascha , Effenberger Ira 
Published: April 2023

Eine wachsende Zahl von Unternehmen setzt auf Digitalisierung, um ihre Prozesse zu optimieren und angesichts zunehmender Unsicherheiten resilienter zu werden. Die Erzeugung und Pflege der dazu eingesetzten digitalen Modelle ist aber mit hohem Aufwand verbunden. Eine flexible KI-basierte Objekterkennung, die nur geringe Ansprüche an die Datenbasis stellt und dem Anwender außerdem Korrekturmöglichkeiten bietet, kann als Schlüsseltechnologie helfen, die bestehenden Hindernisse zu überwinden und die Transformation zu effizienteren Prozessen zu beschleunigen.

More and more companies focus on digitization to optimize their processes and become more resilient in the light of increasing uncertainties. However, generating and updating digital models used for this purpose involves a significant amount of effort. Flexible AI-based object detection places fewer demands on the database while offering additional user correction options. It is the key to overcoming the barriers and accelerating the transformation towards more efficient processes.
Nutritional support in a comprehensive program of prevention and treatment of sarcopenia
Authors: Kurmaev D. P. , Bulgakova S. V. , Treneva E. V. , Kosareva O. V. , Dolgikh Yu. A. , Sharonova L. A. , Chetverikova I. S. 
Published: April 2023

Adequate nutrition with a high protein content is one of the main conditions in the complex treatment of sarcopenia. This review article considers strategies for maintaining the dietary derived protein and amino acids value in patients with sarcopenia. The features of nutritious diet in young, middle-aged and older people including those with sarcopenia are compared and outlined. The possibilities of nutritional supplements of proteins and amino acids in the diet of geriatric patients with sarcopenia are given.
POSTSCRIPTUM: Protocol of Geriatric Rehabilitation in Patients Aged 60 Years and Older Living in Moscow Boarding houses or Nursing homes. Protocol of Multicentral Prospective Study
Authors: Tkacheva O. N. , Runikhina N. K. , Malaya I. P. , Sharashkina N. V. , Ostapenko V. S. , Kotovskaya Yu. V. , Melia A. G. , Mkhitaryan E. A. 
Published: April 2023

Background: GR with implementation of additional geriatric rehabilitation stage has been shown in a number of studies to be efficient in daily functional activities as well as in reducing hospital readmissions and mortality. However, better integration of geriatric care models into clinical practice requires further investigations.Aim: to assess the influence of geriatric rehabilitation on functional activity.Methods: рrotocol POSTSCRIPTUM suggests Multicentral Prospective Study on different protocols for Geriatric Rehabilitationл in Moscow boarding houses or nursing homes. The study consists of 21-days period of active treatment based on the results of complex geriatric assessment and 12-months follow-up period. The study enrolls patients aged 60 years and older, who have indications for geriatric rehabilitation.Conclusion: POSTSCRIPTUM — the 1st Russian study on efficacy of geriatric rehabilitation programs that based on complex geriatric assessment.