bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis of Furo- and Thienoquinolines by Using an Amine Oxidase-Inspired Catalyst
Authors: Maji Biplab , Thorve Pradip Ramdas 
Published: May 2023

AbstractWe report the regioselective synthesis of furo- and thienoquinolines by using an amine oxidase-inspired catalyst (1,10-phenanthroline-5,6-dione) and an abundant Lewis acid (FeCl3) as a co-catalyst. The aerobic amine dehydrogenation proceeds under mild conditions and produces the quinolines in high yields. Mechanistic studies helped to identify the possible reaction intermediates and the specific role of the catalyst in the multistep cascade.
Early Thoracic Endovascular Aortic Repair of Uncomplicated Type B Thoracic Aortic Dissection: An Aorta Team Approach
Authors: Ammar Khawaja A. , McDiarmid Matthew , Richards Lauren , Mewissen Mark W. , Jan M. Fuad , Weiss Eric S. , Bajwa Tanvir 
Published: May 2023

Abstract
Background Although uncomplicated Type B aortic dissection (uTBAD) is traditionally treated with optimal medical therapy (OMT) as per guidelines, recent studies, performed primarily in interventional radiology or surgical operating rooms, suggest superiority of thoracic endovascular aortic repair (TEVAR) over OMT due to recent advancements in endovascular technologies. We report a large, single-center, case control study of TEVAR versus OMT in this population, undertaken solely in a cardiac catheterization laboratory (CCL) with a cardiologist and surgeon. We aimed to determine if TEVAR for uTBAD results in better outcomes compared with OMT.
Methods This was a retrospective chart review of all patients with uTBAD during the last 13 years, with 46 cases (TEVAR group) and 56 controls (OMT group).
Results In the TEVAR group, the procedure duration of 2.5 hours resulted in 100% procedural success for stent placement, with 63% undergoing protective left subclavian artery bypass, 0% mortality or stroke, and a lower readmission rate (1 vs. 2%; p = 0.04 in early TEVAR cases), but a longer length of stay (12.9 vs. 8.5 days: p = 0.006). The risk of all-cause long-term mortality was markedly reduced in the TEVAR group (RR = 0.38; p = 0.01), irrespective of early (<14 days) versus late intervention. On follow-up computed tomography imaging, the false lumen stabilized or decreased in 85% of cases, irrespective of intervention timing.
Conclusion TEVAR performed solely in the CCL is safe and effective, with lower all-cause mortality than OMT. These data, in collaboration with previous data on TEVAR in different settings, call for consideration of an update of practice guidelines.
Early Distal Radius Remodeling after Radius Dome Osteotomy in Madelung's Deformity
Authors: Rus Robert , Scheider Philipp , Farr Sebastian 
Published: May 2023

Abstract
Background Distal radius realignment procedures such as the dome osteotomy have been shown to reliably correct the geometry of this three-dimensional deformity. However, it has not been clarified whether the correction is durable over time. We thus reviewed a prospective Madelung's database and evaluated all patients who received a radius dome osteotomy to see whether there was any loss of correction over time.
Patients and Methods A total of 16 patients with 19 operated wrists were included. Mean age at surgery was 14 years; the most recent radiograph that was considered for analysis was obtained at a mean of 20 months after the index surgery. Three established radiographic deformity parameters (ulnar tilt, lunate subsidence, palmar carpal displacement) were repetitively measured by an independent observer over the course of the postoperative follow-up and compared using the analysis of variance statistics.
Results A mild but nonsignificant worsening of deformity parameters was observed in six patients (32%). Overall, ulnar tilt improved from 50 to 40 degrees after surgery and was 43 degrees at latest follow-up. The values for lunate subsidence were −5.5, 0, and −1.6 mm, respectively. Palmar carpal displacement did not recur after correction (21, 17, and 16 mm, respectively).
Conclusions Frontal plane parameters remodeled to a certain degree, although not in a statistically significant manner, soon after corrective osteotomies in Madelung's deformity. Although mild surgical overcorrection may be warranted in younger patients, it remains unclear if a concomitant distal radial epiphysiodesis would generally be beneficial.
Level of Evidence Level IV
Kidney Stones in Epileptic Children Receiving Ketogenic Diet: Frequency and Risk Factors
Authors: Güzin Yiğithan , Yılmaz Ünsal , Devrim Fatma , Dinçel Nida , Ünalp Aycan 
Published: May 2023

Abstract
Background Although it is a valuable option for children with drug-resistant epilepsy, ketogenic diet (KD) therapy is associated with several side effects. The frequency of kidney stones and risk factors for their development in epileptic children receiving KD is unclear. The aim of this study was to determine the frequency and risk factors for the development of renal stones in children receiving KD therapy.
Methods A total of 95 patients receiving KD were identified. Of these, seven patients were excluded from the study due to the duration of KD being less than 12 months. The remaining 88 children were enrolled in the study.
Results Renal stones were detected in 15 patients (17%), of which 12 (73.3%) received potassium citrate treatment. Two (13.3%) patients needed lithotripsy despite receiving potassium citrate treatment, and one of these, who received potassium citrate treatment for 5 months, developed acute vesicourethral reflux and underwent surgery. No patient discontinued KD due to renal stone development. The serum uric acid concentrations and urine calcium/creatinine ratio did not change significantly over the 24-month follow-up period. Age, gender, etiology, age at seizure onset, duration of KD, mobility status, use of topiramate or zonisamide, and the number of antiepileptic drugs used were not significantly different between patients with and without kidney stones.
Conclusion Renal stone appears to be a common adverse effect of KD therapy. Although adequate hydration and potassium citrate treatment are effective in most patients, lithotripsy and surgery may be required in a minority of patients.
Outcome of Revascularizing the Left Subclavian Artery via Carotid-Subclavian Bypass
Authors: Rylski Bartosz , Matzdorf Monika , Kondov Stoyan , Czerny Martin 
Published: May 2023

Abstract
Background Endovascular thoracic aortic treatment frequently requires extending the proximal landing zone up into the aortic arch with consecutive covering of the left subclavian artery orifice. Our aim was to report on our outcome of left subclavian artery revascularization using carotid-subclavian bypass via lateral access to the subclavian artery.
Methods Patients' charts in our aortic center were screened for all those who had undergone carotid-subclavian bypass during endovascular thoracic aortic repair procedures. We analyzed perioperative complications such as cervical plexus nerve or phrenic nerve injury, bleeding, and primary and follow-up graft patency.
Results Between 2001 and 2020, 118 patients underwent carotid-subclavian bypass implantation. Postoperative complications included left-sided stroke in 3% and axillary, phrenic, and recurrent laryngeal nerve palsy in 3, 2, and 3%, respectively. Carotid-subclavian bypass–related death rate was 0%. Bypass patency was 92 ± 7% at 5 years. We documented nine (8%) bypass late occlusions with one left upper extremity ischemia and one late stroke due to an embolized thrombus formed at the bypass anastomosis. All others were asymptomatic.
Conclusion Carotid-subclavian bypass surgery is associated with very low risk of death, stroke, or any nerve palsy. Lateral access to the left subclavian artery reduces the risk of phrenic nerve injury.
The C-terminal pentapeptide acein analogue (JMV3315) stimulates dopamine release in the brain
Authors: Lucas-Valmalle Charlène , Subra Gilles , Verdié Pascal , Kemel Marie-Lou , Daugé Valérie , Puget Karine , Martinez Jean 
Published: May 2023

We have previously reported the synthesis and biological activity of a newly identified peptide of sequence H–Pro–Pro–Thr–Thr–Thr–Lys–Phe–Ala–Ala–OH called acein that is able to stimulate dopamine release in the brain of rodents in vivo and ex vivo by interacting with angiotensin converting enzyme (ACE). In the present piece of work, we studied the structure–activity relationships of acein using displacement experiments of the labelled ligand [125I]Tyr–Pro–Pro–Thr–Thr–Thr–Lys–Phe–Ala–Ala–OH on guinea pig brain membranes, known to have high-affinity acein binding sites. We determined that the C-terminal pentapeptide H–Thr–Lys–Phe–Ala–Ala–OH is the minimal structure able to interact with high affinity (Ki (inhibitory constant) 13 ± 2 nM) with acein binding sites. Among the analogues of the pentapeptide that were synthesized, the pentapeptide H–Thr–Lys–Tyr–Ala–Ala–OH showed the highest affinity (Ki 3.7 ± 1.0 nM). Accordingly, this pentapeptide was able to stimulate dopamine release from striatal slices taken from the sensorimotor territory of rats.
Modelling intensity volume averaging in ab initio calculations of high harmonic generation
Authors: Hutcheson L , van der Hart H W , Brown A C 
Published: May 2023

Abstract
We present an approach to assess the survival of single-atom effects in the macroscopic high-harmonic generation (HHG) spectrum, by accounting for focal volume averaging. We apply this technique to R-matrix with time-dependence (RMT) studies, which are designed to include the full multielectron response of an atom. Such an approach allows the assessment of which features of an experimentally-measured HHG spectrum of diffuse gases may be traced directly to single-atom effects and vice-versa. While accounting for the phase of harmonics produced at different locations in the focal volume gives the most accurate results, a simplified approach, using a smaller number of RMT calculations, is found to provide comparable conclusions. We apply these approaches to compute intensity-averaged harmonic spectra in two different experimental regimes.
The solenoidal large intensity device (SoLID) for JLab 12 GeV
Authors: Arrington J , Benesch J , Camsonne A , Caylor J , Chen J-P , Covrig Dusa S , Emmert A , Evans G , Gao H , Hansen J-O , Huber G M , Joosten S , Khachatryan V , Liyanage N , Meziani Z-E , Nycz M , Peng C , Paolone M , Seay W , Souder P A , Sparveris N , Spiesberger H , Tian Y , Voutier E , Xie J , Xiong W , Ye Z-Y , Ye Z , Zhang J , Zhao Z-W , Zheng X ,   For the Jefferson Lab SoLID Collaboration
Published: May 2023

Abstract
The solenoidal large intensity device (SoLID) is a new experimental apparatus planned for Hall A at the Thomas Jefferson National Accelerator Facility (JLab). SoLID will combine large angular and momentum acceptance with the capability to handle very high data rates at high luminosity. With a slate of approved high-impact physics experiments, SoLID will push JLab to a new limit at the QCD intensity frontier that will exploit the full potential of its 12 GeV electron beam. In this paper, we present an overview of the rich physics program that can be realized with SoLID, which encompasses the tomography of the nucleon in 3D momentum space from semi-inclusive deep inelastic scattering, expanding the phase space in the search for new physics and novel hadronic effects in parity-violating DIS, a precision measurement of J/ψ production at threshold that probes the gluon field and its contribution to the proton mass, tomography of the nucleon in combined coordinate and momentum space with deep exclusive reactions, and more. To meet the challenging requirements, the design of SoLID described here takes full advantage of recent progress in detector, data acquisition and computing technologies. In addition, we outline potential experiments beyond the currently approved program and discuss the physics that could be explored should upgrades of CEBAF become a reality in the future.
Radiological risk assessment of outdoor 222Rn and 220Rn around rare earth element and uranium mines from northern Vietnam
Authors: Hoang Van-Hiep , Tai Tue Nguyen , Nguyen Thai-Son , Dang Quy Tran , Nguyen Thanh-Duong , Nguyen Van-Dung 
Published: May 2023

Abstract
The outdoor 222Rn and 220Rn concentrations at 320 sampling points at 1 m above the ground in different sites surrounding rare earth element (REE) and uranium mines from northern Vietnam were measured using the RAD7. Results showed that 222Rn concentrations were always higher than 220Rn concentrations with large variation ranges from 25.7 to 573 Bq m−3 and from 18.5 to 385 Bq m−3, respectively. The high correlation between 220Rn and 228Ra concentrations in surface soil of the studied sites were observed. The highest 220Rn and 222Rn concentrations are found at the sampling points of the REE NX-Lai Chau site. The 220Rn and 222Rn activities surrounding the REE mines were found to be higher than those surrounding the uranium mines. The average annual committed effective doses originated from the inhalation of 220Rn and 222Rn outdoor concentrations is about five times higher than the worldwide average value.
Strain fields measurement using frequency domain Savitzky–Golay filters in digital image correlation
Authors: Wu Rong , Li Yanbing , Zhang Shuiqiang 
Published: May 2023

Abstract
Savitzky–Golay (SG) filter is an effective and convenient gradient calculation method employed for full-field strain measurement in digital image correlation (DIC). Currently, the strain field can be conveniently obtained by moving smoothing filtering with SG filters. This is a method of spatial filtering, which offers the advantages of easy implementation and high accuracy. This study proposed a strain calculation method based on frequency domain SG (FD-SG) filtering. Prior to performing FD-SG filtering, data extension operations involving outer-boundary padding and zero-padding were performed on the displacement field data. Similarly, the SG filters template was extended with zero-padding and circularly shift operations. Subsequently, FD-SG filters were generated by applying the fast Fourier transform (FFT) to the expanded SG template. Thereafter, FD-SG filtering was implemented through the multiplication of the displacement in the Fourier-domain by an FD-SG filter. Finally, the strain field was obtained via inverse FFT and valid data interception operation. The simulation and practical experiments confirmed the equivalent accuracy exhibited by FD-SG and spatial domain SG filtering. Thus, the proposed FD-SG filtering method has great potential for real-time strain measurement in DIC.
Charge-to-spin conversion in fully epitaxial Ru/Cu hybrid nanolayers with interface control
Authors: Song Jieyuan , He Cong , Scheike Thomas , Wen Zhenchao , Sukegawa Hiroaki , Ohkubo Tadakatsu , Nozaki Yukio , Mitani Seiji 
Published: May 2023

Abstract
The demonstration of the charge-to-spin conversion, especially with enhanced spin Hall conductivity, is crucial for the development of energy-efficient spintronic devices such as spin–orbit torque (SOT) based magnetoresistive random access memories. In this work, fully epitaxial Ru/Cu heterostructures were fabricated with interface engineering and nanolayer insertions consisting of Cu (1 nm)/Ru (1 nm) structures with different numbers of periods. The atomically controlled interface was confirmed by the high-resolution high-angle annular dark-field scanning transmission electron microscopy, and the epitaxial relationship persists even in the hybrid nanolayer insertion structures. The spin current generation was detected by the measurement of unidirectional spin Hall magnetoresistance, and the effective damping-like spin Hall efficiency (ξ
DL) was further quantitatively evaluated by the spin-torque ferromagnetic resonance with thickness dependence of the ferromagnetic layer. It is found that the sharp interface Ru/Cu film has a sizeable ξ
DL of −2.2% and the insertion of Cu/Ru nanolayers at the interface can increase the ξ
DL value to −3.7%. The former could be attributed to the interface spin–orbit filtering effect and the latter may be further understood by the intrinsic contribution from the local electronic structure tuning due to the lattice distortion near the interface. A large effective spin Hall conductivity is achieved to be (3∼5) × 105

ℏ

2
e

Ω−1 m−1 in the epitaxial Ru/Cu hybrid nanolayers, which is in the same range as that of platinum. This work indicates that the interfacial control with hybrid nanolayer structures can extend the SOT-based materials to highly conductive metals, even with weak spin–orbit interactions, toward high stability, low cost, and low energy consumption for spintronic applications.
Synergistic impacts of Fe/Fe3C and Fe-Nx on high-efficiency microwave-absorbing properties of Fe/Fe3C@NC composites
Authors: Luo Li , Yuan Xiaoyan , Wang Dongsheng , Qiu Xiaoqing 
Published: May 2023

Abstract
The construction of multi-component composites has become an attractive strategy for high-performance microwave absorption through balancing the magnetic and dielectric loss. However, the influences of different components on absorption performance are ambiguous, which has inevitably hampered the widespread applications of microwave absorbents. Herein, we rationally designed the multi-component absorbers of N-doped carbon composited with Fe/Fe3C nanoparticles, and systematically investigated the impacts of Fe/Fe3C nanoparticles and Fe-Nx moieties on the microwave-absorbing capacities. It is found that the coexisitence of Fe/Fe3C and Fe-Nx is indispensable to realize the strong microwave absorption ability by simultaneously enhancing the dielectric and magnetic loss in the frequency range of 2–18 GHz. As expected, our optimal absorber dispersed in paraffin with a filler loading of 15 wt% exhibits the minimum reflection loss (RLmin) value of −49 dB and the maximum effective absorption bandwidth (BWeff) value of 4.2 GHz at a low thickness. Our work specifies the importance and influence of the coexistence between the Fe-Nx configurations and Fe/Fe3C nanoparticles in the carbon-based composites for the superior microwave absorption and inspires the future fabrication of extraordinary materials in the electromagnetic field.
High orientation consistency and adjustable convex width of laser-induced periodic surface structures using picosecond laser pulse trains
Authors: Pan Aifei , Wang Wenjun , Mei Xuesong , Xia Yong , Sun Xiaoyun 
Published: May 2023

Abstract
High orientation consistency and adjustable convex width of the low-spatial-frequency laser-induced periodic surface structures (LSFLs), crucial to the functional surface characteristics, have remained elusive. This paper proposes a new method to fabricate LSFLs with high orientation consistency on the rough surface of titanium by combining laser polishing and laser induction with LSFLs with a tunable convex width via laser melting as the post-treatment. Picosecond pulses trained with a 50-ns interval are applied to regulate the thermal incubation effect and achieve laser polishing and laser nanoscale melting. The melting time of titanium for laser polishing and laser nanoscale melting is determined to be on a microsecond time scale and around 100 ns, respectively. Experimental studies show that the surface texture of titanium lowers the orientation consistency of LSFLs and that its divergence angle is 30°. Picosecond pulses with a sub-pulse number of three are applied to achieve surface polishing and the formation of the rudiment of the LSFLs, followed by the picosecond laser induction. As a result, the divergence angle of LSFLs decreases from 30° to 12°. On this basis, aiming at the problem of the narrow adjustability of the convexity ratio of LSFLs, a nanoscale melting processing method based on picosecond pulse trains with a sub-pulse number of four is proposed, and LSFLs with the tunable convexity ratios from 0.3 to 0.87 are obtained.
Bidirectional feature matching based on deep pairwise contrastive learning for multiparametric MRI image synthesis
Authors: Touati Redha , Kadoury Samuel 
Published: May 2023

Abstract

Objective. Multi-parametric MR image synthesis is an effective approach for several clinical applications where specific modalities may be unavailable to reach a diagnosis. While technical and practical conditions limit the acquisition of new modalities for a patient, multimodal image synthesis combines multiple modalities to synthesize the desired modality. Approach. In this paper, we propose a new multi-parametric magnetic resonance imaging (MRI) synthesis model, which generates the target MRI modality from two other available modalities, in pathological MR images. We first adopt a contrastive learning approach that trains an encoder network to extract a suitable feature representation of the target space. Secondly, we build a synthesis network that generates the target image from a common feature space that approximately matches the contrastive learned space of the target modality. We incorporate a bidirectional feature learning strategy that learns a multimodal feature matching function, in two opposite directions, to transform the augmented multichannel input in the learned target space. Overall, our training synthesis loss is expressed as the combination of the reconstruction loss and a bidirectional triplet loss, using a pair of features. Main results. Compared to other state-of-the-art methods, the proposed model achieved an average improvement rate of 3.9% and 3.6% on the IXI and BraTS’18 datasets respectively. On the tumor BraTS’18 dataset, our model records the highest Dice score of 0.793(0.04) for preserving the synthesized tumor regions in the segmented images. Significance. Validation of the proposed model on two public datasets confirms the efficiency of the model to generate different MR contrasts, and preserve tumor areas in the synthesized images. In addition, the model is flexible to generate head and neck CT image from MR acquisitions. In future work, we plan to validate the model using interventional iMRI contrasts for MR-guided neurosurgery applications, and also for radiotherapy applications. Clinical measurements will be collected during surgery to evaluate the model’s performance.