bluuebunny/crossref_metadata_2025_split huggingface dataset:
Contribution to the building of a weather information service for solar panel cleaning operations at Diass plant (Senegal, Western Sahel)
Authors: Aidara Mohamed Cherif , Fam Pape Abdoulaye , Danso Derrick Kwadwo , Mortey Eric Mensah , Mbaye Amy , Ndiaye Mamadou Lamine , Bonkaney Abdou Latif , Adamou Rabani , Anquetin Sandrine , Diedhiou Arona 
Published: March 2023

Abstract
The accumulation of dust on the surface of solar panels reduces the amount of sunlight reaching the solar cells and results in a decrease in panel performance. To avoid this loss of production and thus, to improve the performance capacity, solar panels must be cleaned frequently. The West African region is well known for its high solar energy potential. However, this potential can be reduced by the high occurrence of dust storms during the year. This article aims to provide a contribution to the construction of a meteorological information service for solar panel cleaning operations at Diass solar plant in Senegal (Western Sahel). It is based on a full year in situ experiment comparing the power loss due to dust between solar panels cleaned at different frequencies and those not cleaned. The model to determine the cleaning frequencies is based on the deposition rate of airborne particles, the concentration of airborne particles, and the density of the dust that has a major impact on the power loss. Cleaning frequencies are presented at seasonal scale because in the study area, dust episodes differ according to the seasons. A cost–benefit analysis is also performed to demonstrate the advantage of using weather information service to support the dust cleaning operations at Diass plant. As results, it is found that cleaning every 3 weeks is required during the dry seasons, December–January–February and March–April–May. During the rainy season, cleaning every 5 weeks is recommended in June–July–August, while in September–October–November cleaning every 4 weeks is sufficient to maintain an optimal performance of the solar panel. The total costs of cleaning operations based on these results are reduced compared to the current costs of cleaning and the benefits are much higher than without cleaning action.
A Revisionist Reading ofThe Goddess: Visual Narrative Power in Chinese Silent Cinema
Authors: Ng Kenny K. K. 
Published: March 2023

AbstractThis article argues for a revisionist reading ofThe Goddessto redirect critical attention to its film form and narrative style. Yet, it also explores the social-economic and technological conditions of filmmaking in early Chinese cinema that circumvented the filmmaker’s aesthetic choices and devices. A political reading of the film within either the leftist-progressive or nationalist agenda is inadequate in explicating the film’s narrative capacity and affective power in engaging social commentary. ReadingThe Goddessas a Chinese manifestation of Hollywood’s maternal melodrama has equally dismissed the film’s contestation of the complex political and ideological discourses in which it was produced. Inspired by a neoformalist approach to studying film form and social reality, this article articulates the working of Wu Yonggang’s cinematic style as a crafted combination of artistic choices and interventions, which are made within the classical Hollywood paradigm and Soviet montage, to define an early Chinese cinematic language that is specific to 1930s Shanghai film industry and Chinese society, the filmmaker’s aesthetic pursuit, and Ruan Lingyu’s stardom.
Critical learning episodes in the EFL classroom: a multimodal (inter)action analytical perspective
Authors: Mejía-Laguna Jorge Andrés 
Published: March 2023

Abstract
The present study centers on exploring how different modes such as speech, gesture, gaze, body posture, and head movement are employed by an EFL teacher and his students during a Critical Learning Episode (CLE). CLEs are brief instances of classroom interaction where the instructor and the researcher believe that learning is being fostered or inhibited. This article is part of a larger qualitative multiple-case study that took place at a private Colombian University. The lesson was videotaped and then analyzed within a Multimodal (Inter)action Analysis framework. Findings indicate that CLEs are created in a highly embodied, multimodal, and ecological manner through different modal configurations. Besides speech and writing, modes such as gestures, posture, gaze, and head movement played not a marginal, but prominent role, in performing various pedagogical classroom activities such as enhancing shared/ focused attention, strengthening alignment, helping teachers and learners to visually make meaning of morphological and syntactical units, and serving as devices to check for understanding.
HDAC5-mediated PRAME regulates the proliferation, migration, invasion, and EMT of laryngeal squamous cell carcinoma via the PI3K/AKT/mTOR signaling pathway
Authors: Yu Lei , Cao Huan , Yang Jian-Wang , Meng Wen-Xia , Yang Chuan , Wang Jian-Tao , Yu Miao-Miao , Wang Bao-Shan 
Published: March 2023

Abstract
Laryngeal squamous cell carcinoma (LSCC) is an aggressive and lethal malignant neoplasm with extremely poor prognoses. Accumulating evidence has indicated that preferentially expressed antigen in melanoma (PRAME) is correlated with several kinds of cancers. However, there is little direct evidence to substantiate the biological function of PRAME in LSCC. The purpose of the current study is to explore the oncogenic role of PRAME in LSCC. PRAME expression was analyzed in 57 pairs of LSCC tumor tissue samples through quantitative real-time PCR, and the correlation between PRAME and clinicopathological features was analyzed. The result indicated that PRAME was overexpressed in the LSCC patients and correlated with the TNM staging and lymphatic metastasis. The biological functions and molecular mechanism of PRAME in LSCC progression were investigated through in vitro and in vivo assays. Functional studies confirmed that PRAME facilitated the proliferation, invasion, migration, and epithelial–mesenchymal transition of LSCC cells, and PRAME also promoted tumor growth in vivo. HDAC5 was identified as an upstream regulator that can affect the expression of PRAME. Moreover, PRAME played the role at least partially by activating PI3K/AKT/mTOR pathways. The above findings elucidate that PRAME may be a valuable oncogene target, contributing to the diagnosis and therapy of LSCC.
Westenfeindlichkeit in den islamischen Ländern
Authors: Aslan Ednan 
Published: March 2023

Zusammenfassung
Dieser Beitrag beschäftigt sich mit der wachsenden Westenfeindlichkeit in den islamischen Ländern, welches derzeit vor allem in Medien und Politik konstruiert wird und die Wahrnehmung der westlichen Staaten und ihrer Werte maßgeblich beeinflusst, so dass die Verwestlichung mit moralischer Dekadenz in der Welt gleichgesetzt wird. Das Ziel dieses Beitrages besteht darin, die politischen und islamistischen Hintergründe der Westenfeindlichkeit zu erschließen und die aktuellen Diskussionen zur Stellung der westlichen Werte in islamisch geprägten Kulturen zu erörtern.
Outcomes of lenvatinib therapy in poorly differentiated thyroid carcinoma
Authors: Roque João , Nunes Silva Tiago , Regala Catarina , Rodrigues Ricardo , Leite Valeriano 
Published: March 2023

Background and objective
Lenvatinib showed promising results in a subgroup of patients with poorly differentiated thyroid carcinoma (PDTC) in the SELECT trial. Our aim was to report the effectiveness and tolerability of lenvatinib in our series of PDTC patients.

Methods
Medical records of eight consecutive patients with PDTC treated with lenvatinib in a single center between January 2019 and October 2022 were retrospectively reviewed. Inclusion criteria were PDTC diagnosis based on Turin criteria and evidence of disease progression in the previous 6 months.

Results
Eight PDTC patients received an average dose of lenvatinib of 18.1 mg for a median duration of treatment of 10.3 months. The baseline Eastern Cooperative Oncology Group performance status was ≥2 in 50% of patients. Two patients had unresectable primary tumor. Seven patients showed extrathyroidal disease, particularly mediastinal lymph nodes (85.7%), lung (71.4%), and bone (71.4%). The disease control rate was 100%, with partial response and stable disease in 12.5 and 87.5%, respectively. The median time to best overall response was 3 months, and the median duration of response was 7.5 months. Median progression-free survival was 12 months and median overall survival was not reached. At 6, 12, and 18 months, overall survival was 87.5, 71.4, and 57.1%, respectively. All patients experienced drug-related adverse effects (AEs). Four (50%) had dose reductions and two (25%) had temporary treatment interruptions. Lenvatinib was stopped in two patients due to grade ≥3 AEs.

Conclusion
Lenvatinib is an effective treatment for real-world PDTC patients. Adequate management of comorbidities and AEs increases treatment tolerability and minimizes dose reductions.
Der Vermögenserwerb in der deutschen Investitionskontrolle
Authors: Salaschek Uwe , Schipke Maximilian 
Published: March 2023

Zusammenfassung
Der Beitrag stellt die Anwendung der deutschen Investitionskontrolle auf den Erwerb von Vermögensgegenständen in Abgrenzung zum Erwerb von Unternehmensanteilen dar. Die Ergänzung des § 55 Abs. 1a AWV und des § 60 Abs. 1a AWV durch die 15. AWV-Änderungs-VO haben diesbezüglich keine ausreichende Klarheit geschaffen. Fest steht zwar, dass der Vermögenserwerb beim Kauf eines abgrenzbaren Betriebsteils von der Investitionskontrolle erfasst wird. Unter welchen Umständen hingegen der Erwerb einzelner Vermögensgegenstände erfasst wird, bleibt der Auslegung durch den Rechtsanwender überlassen. Dies führt nicht zuletzt wegen des strafbewehrten Vollzugsverbots zu erheblicher Rechtsunsicherheit – insbesondere bei Transaktionen, die den Erwerb immaterieller Betriebsmittel, wie z. B. Technologien und IP-Rechte, zum Gegenstand haben. Die für die deutsche Fusionskontrolle maßgeblichen Entwicklungen können allenfalls teilweise übertragen werden und auch die internationale Investitionskontrollpraxis ist wenig einheitlich.
Sonderzivil(prozess)recht für kartellrechtliche Schadensersatzansprüche?
Authors: Mallmann Roman A. , Leinemann Franziska 
Published: March 2023

Zusammenfassung
In Kartellschadensersatzprozessen gelten die allgemeinen zivil- und zivilprozessrechtlichen Grundlagen. Diese werden bisweilen von der Prämisse des Private Enforcements und des effet utile überlagert. Die Verfasser diskutieren anhand ausgewählter Beispiele, inwieweit deshalb eine den Anspruchstellern entgegenkommende Anwendung des Zivil(prozess)rechts geboten beziehungsweise gerechtfertigt ist. Zunächst befassen sie sich mit der Darlegung und dem Beweis der streitgegenständlichen Bezugsvorgänge sowie der tatsächlichen Vermutung eines kartellbedingten Schadens, die sich in der Rechtsprechung etabliert hat. Ferner greifen sie die Tendenz auf, das Beweisrecht kartellrechtsspezifisch weiterzuentwickeln. Sie betrachten zudem den Vorstoß einzelner Gerichte, den Kartellschaden ohne Sachverständigengutachten selbst zu schätzen.
Auf der Grundlage dieser Bestandsaufnahme meinen die Verfasser, dass für ein Sonderzivil- beziehungsweise -zivilprozessrecht in Kartellschadensersatzfällen kein Bedürfnis besteht und verneinen somit die im Titel gestellte Ausgangsfrage.
Kartellrechtsanwendung durch Regulierungsbehörden und regulierungsbehördliche Vorverfahren für Kartellzivilklagen
Authors: Ante Johann 
Published: March 2023

Zusammenfassung

Leitsatz des Gerichts:

Art. 30 RL 2001/14/EG des Europäischen Parlaments und des Rates vom 26. Februar 2001 über die Zuweisung von Fahrwegkapazität der Eisenbahn und die Erhebung von Entgelten für die Nutzung von Eisenbahninfrastruktur in der durch die RL 2007/58/EG des Europäischen Parlaments und des Rates vom 23. Oktober 2007 geänderten Fassung ist wie folgt auszulegen:
Er steht dem nicht entgegen, dass die nationalen Gerichte bei der Entscheidung über eine Klage auf Rückzahlung der Entgelte für die Nutzung von Infrastruktur gleichzeitig Art. 102 AEUV und das einzelstaatliche Wettbewerbsrecht anwenden, sofern die zuständige Regulierungsstelle vorher über die Rechtmäßigkeit der betreffenden Entgelte entschieden hat. Insoweit sind die nationalen Gerichte zur loyalen Zusammenarbeit verpflichtet; sie müssen bei ihrer Würdigung die Entscheidungen der zuständigen Regulierungsstelle berücksichtigen und sich bei der Begründung ihrer eigenen Entscheidungen mit dem gesamten Inhalt der ihnen vorgelegten Akten auseinandersetzen.
Volume and Severity of Pediatric COVID-19 Hospitalizations in the United States
Authors: Milliren Carly E. , Ozonoff Al 
Published: March 2023

OBJECTIVES
Using administrative data from pediatric hospitals in the United States, we examined trends in coronavirus disease 2019 (COVID-19) hospitalizations and severity of disease among children.

METHODS
We extracted data from the Pediatric Health Information System for hospitalized patients less than 12 years old with COVID-19 (identified by primary or secondary International Classification of Diseases-10 diagnosis code U07.1) admitted from April 2020 to August 2022. We examined weekly trends in COVID hospitalization volume overall and by ICU utilization as a measure of severe disease and by COVID diagnosis hierarchy (primary versus secondary) as a proxy for incidental admissions. We estimated the annualized trend in the ratio of hospitalizations requiring, versus not requiring, ICU care and the trend in ratio of hospitalizations with a primary versus secondary COVID diagnosis.

RESULTS
We included 38 160 hospitalizations across 45 hospitals. Median age was 2.4 years (interquartile range = 0.7–6.6). Median length of stay was 2.0 days (interquartile range = 1–4). ICU-level care was required for 18.9% and 53.8% had a primary diagnosis of COVID-19. The ratio of ICU to non-ICU admissions declined by 14.5% annually (95% confidence interval: −21.7% to −7.26%; P &lt; .001), whereas the ratio of primary to secondary diagnosis was stable (11.7% annually; 95% confidence interval: −8.83% to 32.4%; P = .26).

CONCLUSIONS
Periodic increases in pediatric COVID-19 hospitalizations with are evident. However, there is no evidence of corresponding increase in severity of illness that may provide context for recent reports of increasing pediatric COVID hospitalizations in addition to health policy implications.
Dating Violence Prevention for Juvenile-Justice Involved Females: A Hybrid Trial
Authors: Rizzo Christie J. , Collibee Charlene , Barker David , Houck Christopher , Kemp Kathleen , Tolou-Shams Marina , Zlotnick Caron , Brown Larry K. 
Published: March 2023

OBJECTIVE
The primary objective of this hybrid I clinical trial of Date SMART (Date Skills to Manage Aggression in Relationships for Teens) was to reduce adolescent dating violence (ADV) among juvenile-justice involved females over 1 year. Secondary objectives were to determine if the intervention reduced sexual risk behavior and delinquency. Last, we evaluate system buy-in vis à vis mandated referrals to the program.

METHODS
Participants were females, ages 14 to 18 (N = 240), involved in a family court in the Northeast United States. The Date SMART group intervention consisted of cognitive-behavioral skill building, and the knowledge-only comparison group consisted of psychoeducation regarding sexual health, ADV, mental health and substance use.

RESULTS
Court mandates to intervention were common (41%). Among those with ADV exposure, Date SMART participants reported fewer acts of physical and/or sexual ADV (rate ratio, 0.57; 95% confidence interval [CI], 0.33–0.99) and cyber ADV (rate ratio, 0.75; 95% CI, 0.58–0.96) at follow-up, relative to control. There were significant reductions in the number of vaginal and/or anal sex acts reported by Date SMART participants relative to control (rate ratio, 0.81; 95% CI 0.74–0.89). In the overall sample, within group reductions in some ADV behaviors and delinquency were observed in both conditions.

CONCLUSIONS
Date SMART was seamlessly integrated into the family court setting and received stakeholder buy-in. Although not superior to control as a primary prevention tool, Date SMART was effective in reducing physical and/or sexual ADV, and cyber ADV, as well as vaginal and/or anal sex acts, among females with ADV exposure over 1 year.
A Educação Sexual nas diferentes versões da Base Nacional Comum Curricular: Da abertura ao silenciamento em torno da temática
Authors: Vicente Luciane da Silva 
Published: March 2023

O presente estudo tem por objetivo analisar as perspectivas de educação sexual prescritas em diferentes versões da Base Nacional Comum Curricular (BNCC) e apresentar a percepção de professores sobre contexto de narrativas e disputas que intermediaram sua construção. A educação sexual foi tema amplamente debatido e contemplado nas versões preliminares da BNCC. No entanto, a atuação incisiva das bancadas políticas conservadoras, culminou na retirada dos conceitos de gênero e de orientação sexual, deixando de evidenciar dimensões importantes no documento final. Compreende-se que a omissão dessas questões nos referenciais curriculares favorece a persistência da intolerância contra a diversidade sexual e enfraquece o combate ao preconceito e discriminações arraigados em nossa sociedade. No que se refere metodologia, adotou-se a abordagem qualitativa, que inclui como procedimento: pesquisa bibliográfica, análise documental e de um conjunto de entrevistas com professores que atuam no ensino fundamental para coleta de dados. Para análise dos dados buscamos a articulação entre as técnicas de pesquisa qualitativa e a Análise do Discurso, orientada pelo ciclo de políticas formulado por Stephen Ball e Richard Bowe.
Alterations in the Circulating Proteome Associated with Albuminuria
Authors: Kiernan Elizabeth , Surapaneni Aditya , Zhou Linda , Schlosser Pascal , Walker Keenan A. , Rhee Eugene P. , Ballantyne Christie M. , Deo Rajat , Dubin Ruth F. , Ganz Peter , Coresh Josef , Grams Morgan E. 
Published: March 2023

Significance Statement
We describe circulating proteins associated with albuminuria in a population of African American Study of Kidney Disease and Hypertension with CKD (AASK) using the largest proteomic platform to date: nearly 7000 circulating proteins, representing approximately 2000 new targets. Findings were replicated in a subset of a general population cohort with kidney disease (ARIC) and a population with CKD Chronic Renal Insufficiency Cohort (CRIC). In cross-sectional analysis, 104 proteins were significantly associated with albuminuria in the Black group, of which 67 of 77 available proteins were replicated in ARIC and 68 of 71 available proteins in CRIC. LMAN2, TNFSFR1B, and members of the ephrin superfamily had the strongest associations. Pathway analysis also demonstrated enrichment of ephrin family proteins.

Background
Proteomic techniques have facilitated understanding of pathways that mediate decline in GFR. Albuminuria is a key component of CKD diagnosis, staging, and prognosis but has been less studied than GFR. We sought to investigate circulating proteins associated with higher albuminuria.

Methods
We evaluated the cross-sectional associations of the blood proteome with albuminuria and longitudinally with doubling of albuminuria in the African American Study of Kidney Disease and Hypertension (AASK; 38% female; mean GFR 46; median urine protein-to-creatinine ratio 81 mg/g; n=703) and replicated in two external cohorts: a subset of the Atherosclerosis Risk in Communities (ARIC) study with CKD and the Chronic Renal Insufficiency Cohort (CRIC).

Results
In cross-sectional analysis, 104 proteins were significantly associated with albuminuria in AASK, of which 67 of 77 available proteins were replicated in ARIC and 68 of 71 available proteins in CRIC. Proteins with the strongest associations included LMAN2, TNFSFR1B, and members of the ephrin superfamily. Pathway analysis also demonstrated enrichment of ephrin family proteins. Five proteins were significantly associated with worsening albuminuria in AASK, including LMAN2 and EFNA4, which were replicated in ARIC and CRIC.

Conclusions
Among individuals with CKD, large-scale proteomic analysis identified known and novel proteins associated with albuminuria and suggested a role for ephrin signaling in albuminuria progression.
Potassium Activates mTORC2-dependent SGK1 Phosphorylation to Stimulate Epithelial Sodium Channel: Role in Rapid Renal Responses to Dietary Potassium
Authors: Saha Bidisha , Shabbir Waheed , Takagi Enzo , Duan Xin-Peng , Leite Dellova Deise Carla Almeida , Demko John , Manis Anna , Loffing-Cueni Dominique , Loffing Johannes , Sørensen Mads Vaarby , Wang Wen-Hui , Pearce David 
Published: March 2023

Significance Statement
Rapid renal responses to ingested potassium are essential to prevent hyperkalemia and also play a central role in blood pressure regulation. Although local extracellular K+ concentration in kidney tissue is increasingly recognized as an important regulator of K+ secretion, the underlying mechanisms that are relevant in vivo remain controversial. To assess the role of the signaling kinase mTOR complex-2 (mTORC2), the authors compared the effects of K+ administered by gavage in wild-type mice and knockout mice with kidney tubule-specific inactivation of mTORC2. They found that mTORC2 is rapidly activated to trigger K+ secretion and maintain electrolyte homeostasis. Downstream targets of mTORC2 implicated in epithelial sodium channel regulation (SGK1 and Nedd4-2) were concomitantly phosphorylated in wild-type, but not knockout, mice. These findings offer insight into electrolyte physiologic and regulatory mechanisms.

Background
Increasing evidence implicates the signaling kinase mTOR complex-2 (mTORC2) in rapid renal responses to changes in plasma potassium concentration [K+]. However, the underlying cellular and molecular mechanisms that are relevant in vivo for these responses remain controversial.

Methods
We used Cre-Lox–mediated knockout of rapamycin-insensitive companion of TOR (Rictor) to inactivate mTORC2 in kidney tubule cells of mice. In a series of time-course experiments in wild-type and knockout mice, we assessed urinary and blood parameters and renal expression and activity of signaling molecules and transport proteins after a K+ load by gavage.

Results
A K+ load rapidly stimulated epithelial sodium channel (ENaC) processing, plasma membrane localization, and activity in wild-type, but not in knockout, mice. Downstream targets of mTORC2 implicated in ENaC regulation (SGK1 and Nedd4-2) were concomitantly phosphorylated in wild-type, but not knockout, mice. We observed differences in urine electrolytes within 60 minutes, and plasma [K+] was greater in knockout mice within 3 hours of gavage. Renal outer medullary potassium (ROMK) channels were not acutely stimulated in wild-type or knockout mice, nor were phosphorylation of other mTORC2 substrates (PKC and Akt).

Conclusions
The mTORC2-SGK1-Nedd4-2-ENaC signaling axis is a key mediator of rapid tubule cell responses to increased plasma [K+] in vivo. The effects of K+ on this signaling module are specific, in that other downstream mTORC2 targets, such as PKC and Akt, are not acutely affected, and ROMK and Large-conductance K+ (BK) channels are not activated. These findings provide new insight into the signaling network and ion transport systems that underlie renal responses to K+
in vivo.