bluuebunny/crossref_metadata_2025_split huggingface dataset:
Estimation of carbon footprint of longline and lines fisheries in the Indonesia FMA 573-Indian Ocean based at Palabuhanratu Fishing Port
Authors: Anggawangsa R F , Hargiyatno I T , Suryanto  , Widodo A A 
Published: February 2023

Abstract
Being convinced that the fisheries industry produces carbon footprint (CFP), the Center for Fisheries Research carried out research in 2021 to estimate the CFP of longline and lines tuna fisheries based in Palabuhanratu Fishing Port. The port is one of several important bases for tuna longlines and lines fishing fleets operated in the Indonesia FMA 753 (Indian Ocean). The port was selected because of the availability and adequacy of data for estimating the CFP of tuna longline and lines boats. This research aims to estimate the CFP of industrial tuna fisheries represented by both longline fisheries and lines fisheries. The estimate of greenhouse gases was quantified following procedures for the tier II emission factor. The analysis concluded that the average CPF of the two types of tuna fisheries in Palabuhanratu in the last seven years is 603.38 and 508.58 KgCO2eq/Kg of fish, respectively.
Preliminary study of microplastics content in the digestive tract of sea cucumber from Demak Waters
Authors: Hartati R , Widianingsih W , Zainuri M , Supriyo E 
Published: February 2023

Abstract
As a marine delicacy, sea cucumbers were often eaten raw in many part of the world and they have been reported to ingest microplastic. This study aimed to determine the microplastics in the digestive system of sea cucumbers from Demak Waters. The ten samples of Acaudina sp were taken using a bottom dredge from Wulan Estury and put in the glass-bottles samples. In the laboratory, the digestive tract was taken out from the sea cucumber, divided into 7 parts, and pooled in the glass beaker. Microplastics were digested with KOH and incubated at 40 °C for 24 hours. Then, the digestion solution was filtered through a sterile cellulose nitrate filter paper by vacuum filtration. The microplastics obtained were observed for their physical characteristics (density, shape and colour) under the microscope. The density of microplastics were varied among the part of digestive tract. They consisted of fragments, fiber, and pellets. The colour of microplastics were varied but dominated by the blue. As a deposit feeder, the sea cucumber might ingest the microplastics in the sediment they fed on.
Comparative image analysis approaches to assess ecological effects of macroalgal removal on inshore reefs of Magnetic Island, Australia
Authors: Hermanto B , Bourne D G , Smith H 
Published: February 2023

Abstract
Macroalgae removal is a proposed management option in the GBR to reverse declines in inshore coral reef health. Automated image analysis (AIA) is a valuable tool to assess benthic community assemblages. This study compared the accuracy of benthic community assemblages assessed through the AIA program CoralNet to manual image analysis. The ecological effect of macroalgae removal on benthic community composition was also investigated on established permanent quadrats (5x5 m) for reefs at Florence and Arthur Bay, Magnetic Island. Control and treatment quadrats (n=3 respectively) were photographed before and after macroalgae removal over 6 months. The results obtained by AIA and manual approaches were consistent, with macroalgae cover is approximately 77%-87% in all quadrats before macroalgal removal. Through the monitoring period, a small increase in coral cover in the macroalgal removal quadrats was observed in Florence and Arthur Bay (an increase of 1.8% and 0.1%, respectively). CoralNet was demonstrated to be robust for assessing reef benthic cover with no significant difference in recorded benthic categories when compared to the manual approach. CoralNet was accurate for identifying broad benthic categories, but less effective than manual image analyses for lower taxonomic categories (i.e., genus or species level).
Harvesting trend of the pelagic fish resource in North Maluku Province waters (IFMA 715)
Authors: Mahulette R T , Nugroho D 
Published: February 2023

Abstract
Sustainable harvesting of the marine living resources in North Maluku Province would provide employment and economic benefit to broad-scale coastal communities. The pelagic fish resource has been the backbone of marine capture fisheries in this area for years. Mapping the ten years of harvesting would enhance the common baseline to improve the existing instrument for fisheries management. Data limited fisheries approach based on landing records was applied to perform the harvest trend of these typical fisheries. The analysis was performed based on four representative groups of species (skipjack, kawa-kawa, scads, and anchovies) and four main fishing gears regularly recorded (pelagic seiner, beach seine, pole and line, and gillnet) for more than one decade. The result showed that the harvesting system slightly increased since 2002, indicated by 170 % in landing volume and 4 % in the number of gears. The estimated value of landing in 2020 at about 2.6 trillion IDR significantly increased compared to 203 billion IDR in 2002. This multi-scale harvesting trend of pelagic fisheries could increase fishing mortality without regular monitoring and evaluation. It is suggested that improving the existing fisheries management plan for the sustainability of the pelagic fisheries business should be evaluated regularly to provide a long-term beneficiary for coastal community fishery livelihood dependence for the North Moluccas Province.
The definition of small fisher: legal conflicts and their impacts
Authors: Solihin A , Afriansyah A , Bilqis A , Susanto H A 
Published: February 2023

Abstract
The management of small fisher in Indonesia is faced with unclear definition boundaries. Furthermore, the unclear boundaries will have impacts on the rights and obligations of small fisher as regulated in Indonesian laws and regulations. Small Scale Fisher (SSF) has been contributing to poverty alleviation, food security, livelihoods, local economy, and human rights. This is appropriate with fishing activities in Indonesia, where captured fishing fleet is dominated by small scale fisher. This study aims to map the definition of small fisher based on the government regulation, identify the impact of different definition of small fisher, and recommend the arrangement planning of small fisher in fishing activities. Normative juridical and comparative analysis are applied in this study. The result shows that there are various limitations of small fisher definition that impact illegal fishing practices, where small fisher are accused due to the absence of ship registration ownership documents. Therefore, synchronization needs to be implemented in relation with small scale fisher termination boundary to prevent one sided interpretation. Legal clarity is required with regards to the authorization of fishing vessel registration owned by small scale fisher
Social-ecological connectivity and management factors of puerulus (Panulirus spp.) fisheries in the Western Coastal Waters of Lampung Province
Authors: Lestari P A , Adrianto L , Zairion Z , Effendi I 
Published: February 2023

Abstract
Access limitation to capture lobster puerulus needs to be done to sustain the utilization of the resources, increase fishermen’s income and preserve the abundance of puerulus in the Western Coastal Waters of Lampung Province. The management of puerulus resources in these waters does not seem to have been well integrated within the framework of the social-ecological system (SES) of fishery resources. This study aims to analyze SES components and connectivity of lobster puerulus and identify strategic factors to be used in the context of fisheries management of lobster (Panulirus spp.). The research was conducted between October until November 2021 in West Coast Regency, Lampung Province, using SES approach. From the results, we have been revealed that there is a strong interaction and influence between the resources actor component (RA) and the resources unit (RU) in the context of the dynamics of the resources system (RS), but tends to be weak in the framework of the governance of the resource (RG). The management strategy is carried out through good collaboration between the government and resources actor to maintain puerulus abundance.
Numerical analysis of shock characteristics control based on bump
Authors: Li Dawei , Yu Kaibo , Wang Xiao , Gao Yuanbo 
Published: February 2023

Abstract
The effects of bump control on shock aerodynamic characteristics have been investigated by simulations. A bump control that based on the changes of local upper surface of two-dimensional (2D) airfoil or three-dimensional (3D) wing model has been applied to affect the shock intensity and position. The simulation results are close of other experiment when the calculate parameters are same with each other. The simulations show that the drag and lift characteristics can be improved with the bump control, and the results of improvement strongly depend on control parameters. For the 2D RAE2822 airfoil, the optimal control position of the bump control must keep close to the position of the shock wave. The 3D local bump that located on 80% wing span wise and closed to the tip can acquire a batter control results for the 3D RAE2822 wing model.
A facile method to pattern silver nanowires on sandpaper and its application in pressure sensors
Authors: Wang Li , Geng Yang 
Published: February 2023

Abstract
A conductive layer deposited on a rough surface can effectively improve the performance of a pressure sensor; however, its further application requires patterning of the conductive layer to obtain the corresponding electrical layout. In this paper, a facile patterning method with few steps was proposed for patterning silver nanowires on sandpaper. This method employed a photocurable resin as the key material to define the pattern using a photomask under UV exposure. It was found that greater cure depths and narrower light-transmitting areas require longer exposure times. A pattern with linewidth of approximately 40 μm was obtained on M-400 sandpaper (M-400 stands for the mesh number). Based on this method, pressure sensors consisting of interdigital electrodes with rough surfaces and sponge-sensing layers were fabricated. The best resulting sensor exhibited a high-pressure sensitivity of 21.89 kPa−11 for less than 2 kPa, a low detection limit (24.5 Pa), low operating voltage (0.01 V), and short response time (84 ms). Moreover, this patterning method has no special requirements for materials and substrates and thus can be applied to pattern other materials on rough or smooth surface substrates.
Structural dynamics of Schottky and Frenkel defects in CeO2: a density-functional theory study
Authors: Smith Thomas , Moxon Samuel , Tse Joshua S , Skelton Jonathan M , Cooke David J , Gillie Lisa J , da Silva E Lora , Harker Robert M , Storr Mark T , Parker Stephen C , Molinari Marco 
Published: February 2023

Abstract
Cerium dioxide CeO2 (ceria) is an important material in catalysis and energy applications. The intrinsic Frenkel and Schottky defects can impact a wide range of material properties including the oxygen storage capacity, the redox cycle, and the ionic and thermal transport. Here, we study the impact of Frenkel and Schottky defects on the structural dynamics and thermal properties of ceria using density functional theory. The phonon contributions to the free energy are found to reduce the defect formation free energies at elevated temperature. The phonon dispersions of defective CeO2 show significant broadening of the main branches compared to stoichiometric ceria. Phonon modes associated with the defects are identifiable in the infrared spectra through characteristic shoulders on the main features of the stoichiometric fluorite structure. Finally, the presence of Frenkel and Schottky defects are also found to reduce the thermal conductivity by up to 88% compared to stoichiometric CeO2.
Cobalt nickel boride as electrocatalyst for the oxidation of alcohols in alkaline media
Authors: Braun Michael , Chatwani Mohit , Kumar Piyush , Hao Yun , Sanjuán Ignacio , Apostoleri Ariadni-Aikaterini , Brix Ann Cathrin , Morales Dulce M , Hagemann Ulrich , Heidelmann Markus , Masa Justus , Schuhmann Wolfgang , Andronescu Corina 
Published: February 2023

Abstract
A mixed Co and Ni boride precursor was synthesized via chemical reduction and subsequently annealed at 400 or 500 °C with or without prior addition of the monomer benzoxazine (BO). The resulting mixed CoNiB materials were investigated as electrocatalysts for three alcohol oxidation reactions (AOR) in alkaline electrolyte: the oxidation of glycerol (GOR), ethylene glycol (EGOR) and ethanol (EOR). Comparison of the rotating disk electrode (RDE) cyclic voltammograms for the different catalysts revealed that CoNiB annealed at 500 °C without the addition of BO exhibited the lowest overpotentials in AORs at 10 mA cm−2, promoting GOR at 224 ± 6 mV lower potential compared to OER. When pyrolysis was conducted at 400 °C, the BO-containing catalyst showed a significant increase in the electrocatalytic activity for the AORs compared to the CoNiB catalyst only. The product selectivity on the different catalysts was investigated in a batch-type reactor with flow recirculation revealing formate as the main oxidation product during GOR and EGOR with faradaic efficiencies (FE) in a range of 60%–80%, while acetate was obtained during EOR (FE ∼ 85%–90%). The electrode potential, electrolyte composition and the type of ionomer were explored with respect to their influence on the GOR selectivity. The use of different ionomers resulted in significant differences in the activity trends between RDE and the batch-type reactor with flow recirculation measurements, indicating a strong influence of the two different substrates used, namely glassy carbon and carbon paper on the catalyst formation and thus on the recorded electrochemical activity.
Machine-learning approach for quantified resolvability enhancement of low-dose STEM data
Authors: Gambini Laura , Mullarkey Tiarnan , Jones Lewys , Sanvito Stefano 
Published: February 2023

Abstract
High-resolution electron microscopy is achievable only when a high electron dose is employed, a practice that may cause damage to the specimen and, in general, affects the observation. This drawback sets some limitations on the range of applications of high-resolution electron microscopy. Our work proposes a strategy, based on machine learning, which enables a significant improvement in the quality of Scanning Transmission Electron Microscope images generated at low electron dose, strongly affected by Poisson noise. In particular, we develop an autoencoder, trained on a large database of images, which is thoroughly tested on both synthetic and actual microscopy data. The algorithm is demonstrated to drastically reduce the noise level and approach ground-truth precision over a broad range of electron beam intensities. Importantly, it does not require human data pre-processing or the explicit knowledge of the dose level employed and can run at a speed compatible with live data acquisition. Furthermore, a quantitative unbiased benchmarking protocol is proposed to compare different denoising workflows.
Making Sense of Late Tissue Nodules Associated With Hyaluronic Acid Injections
Authors: Goodman Greg J , McDonald Cara B , Lim Adrian , Porter Catherine E , Deva Anand K , Magnusson Mark , Patel Anita , Hart Sarah , Callan Peter , Rudd Alice , Roberts Stefania , Wallace Katy , Bekhor Philip , Clague Michael , Williams Linda , Corduff Niamh , Wines Nina , Al-Niaimi Firas , Fabi Sabrina G , Studniberg Howard M , Smith Saxon , Tsirbas Angelo , Arendse Sean , Ciconte Antoinette , Poon Terence 
Published: February 2023

Abstract

Background
The pathogenesis of delayed-onset tissue nodules (DTNs) due to hyaluronic acid (HA) injections is uncertain.

Objectives
To formulate a rational theory for DTN development and their avoidance and treatment.

Methods
A multidisciplinary and multicountry DTN consensus panel was established, with 20 questions posed and consensus sought. Consensus was set at 75% agreement.

Results
Consensus was reached in 16 of 20 questions regarding the pathogenesis of DTNs, forming the basis for a classification and treatment guide.

Conclusions
The group believes that filler, pathogens, and inflammation are all involved in DTNs and that DTNs most likely are infection initiated with a variable immune response. Injected filler may incorporate surface bacteria, either a commensal or a true pathogen, if the skin barrier is altered. The initially high molecular weight HA filler is degraded to low molecular weight HA (LMWHA) at the edge of the filler. Commensals positioned within the filler bolus may be well tolerated until the filler is degraded and the commensal becomes visible to the immune system. LMWHA is particularly inflammatory in the presence of any local bacteria. Commensals may still be tolerated unless the immune system is generally heightened by viremia or vaccination. Systemic pathogenic bacteremia may also interact with the filler peripheral LMWHA, activating Toll-like receptors that induce DTN formation. Given this scenario, attention to practitioner and patient hygiene and early systemic infection treatment deserve attention. Classification and treatment systems were devised by considering each of the 3 factors—filler, inflammation, and infection—separately.

Level of Evidence: 4
Efficacy of downtitration or treatment withdrawal compared with continuous dosing after successful treatment with baricitinib in patients with moderate-to-severe atopic dermatitis in a randomized substudy from the long-term extension study BREEZE-AD3
Authors: Reich Kristian , Simpson Eric , Wollenberg Andreas , Bissonnette Robert , Abe Masatoshi , Cardillo Tracy , Janes Jonathan , Sun Luna , Chen Sherry , Silverberg Jonathan I 
Published: February 2023

Abstract

Background
Baricitinib, an oral, selective Janus kinase 1/2 inhibitor, demonstrated long-term efficacy in moderate-to-severe atopic dermatitis in an ongoing double-blind, phase III, long-term extension study, BREEZE-AD3 (NCT03334435).

Objectives
To evaluate the efficacy and safety of downtitration and treatment withdrawal in a substudy of BREEZE-AD3.

Methods
The substudy included patients (N = 526) treated with baricitinib 4 mg or 2 mg at entry into BREEZE-AD3 who achieved a validated Investigator Global Assessment for Atopic Dermatitis (vIGA-AD®) scale score of 0 (clear), 1 (almost clear) or 2 (mild) at week 52. Patients treated with baricitinib 4 mg were rerandomized to baricitinib 4 mg (continuous dosing), baricitinib 2 mg (downtitration) or placebo (treatment withdrawal, 4-mg cohort), and patients treated with baricitinib 2 mg were rerandomized to baricitinib 2 mg (continuous dosing), baricitinib 1 mg (downtitration), or placebo (treatment withdrawal, 2-mg cohort). After 16 weeks, we assessed the proportion of patients with vIGA-AD® 0/1, vIGA-AD® 0/1/2, vIGA-AD® ≥ 3 (loss of response; criterion to readminister the original baricitinib dose) and for patients who were readministered the original baricitinib dose, we assessed the proportion of patients who recaptured vIGA-AD® 0/1/2 within 16 weeks of treatment readministration (patients in the continuous dosing maintained the same dose).

Results
For the continuous dosing, downtitration, and treatment withdrawal groups 51%, 45% and 30% of patients in the 4-mg cohort achieved vIGA-AD® 0/1 and 87%, 61% and 50% of patients achieved vIGA-AD® 0/1/2, respectively. For the 2-mg cohort, the respective proportions of patients were 48%, 42% and 25% for vIGA-AD® 0/1 and 92%, 71% and 45% for vIGA-AD® 0/1/2. The respective proportions of patients with vIGA-AD® ≥ 3 were 39%, 49% and 56% in the 4-mg cohort and 41%, 41% and 64% in the 2-mg cohort. Of those who were readministered the original baricitinib dose, the proportions of patients who recaptured vIGA-AD® 0/1/2 among the continuous dosing, downtitration, and treatment withdrawal groups were 80%, 85% and 88% in the 4-mg cohort and 90%, 56% and 86% in the 2-mg cohort, respectively.

Conclusions
Baricitinib allows flexibility for patients to downtitrate or stop treatment. For patients who downtitrated treatment, the majority maintained efficacy through 16 weeks. Most patients who lost efficacy with downtitration or treatment withdrawal achieved clinically relevant efficacy upon readministration of their original dose.
The concomitant use of proton pump inhibitors and BRAF/MEK inhibitors in metastatic melanoma
Authors: Poizeau Florence , Balusson Frédéric , Lemaitre Florian , Tron Camille , Pracht Marc , Russo David , Dinulescu Monica , Lesimple Thierry , Oger Emmanuel , Dupuy Alain 
Published: February 2023

Abstract

Background
Proton-pump inhibitors (PPIs) are commonly used by patients with cancer, although they could reduce the absorption of oral anticancer targeted therapies. The US Food and Drug Administration states that the effect of PPIs on the efficacy of dabrafenib use by patients with metastatic melanoma is unknown. As a precautionary measure, the European Society for Medical Oncology recommends avoiding PPIs for patients receiving dabrafenib.

Objectives
To determine the effect of the concomitant use of PPIs and BRAF/MEK inhibitors in patients with metastatic melanoma.

Methods
Patients with advanced melanoma receiving BRAF/MEK inhibitors as first-line treatments between 2015 and 2017 in France were selected using the French National Health Insurance database. We compared time-to-treatment discontinuation (TTD) and overall survival (OS) according to concomitant PPI exposure. We balanced the baseline characteristics of patients exposed and nonexposed to PPIs using an overlap weighting method based on a propensity score.

Results
The metastatic melanoma cohort comprised 1028 patients receiving BRAF/MEK inhibitors, including 361 (35.1%) patients using PPIs. PPI users had more comorbidities and a more severe metastatic disease. After having equally distributed metastatic sites and comorbidities across patients exposed and nonexposed to PPIs, concomitant PPI use was not associated with shorter TTD [weighted hazard ratio (wHR) 1.03, 95% confidence interval (CI) 0.86–1.24] or OS (wHR 1.11, 95% CI 0.88–1.39). Consistent results were observed when restricting the population to patients receiving dabrafenib, or when narrowing exposure to PPIs with stronger inhibition of cytochromes.

Conclusions
In a population-based cohort of patients with advanced melanoma, the concomitant use of PPIs and BRAF/MEK inhibitors was not associated with worse outcome.