bluuebunny/crossref_metadata_2025_split huggingface dataset:
Blood Milieu in Acute Myocardial Infarction Reprograms Human Macrophages for Trauma Repair
Authors: Fontaine Margaux A. C. , Jin Han , Gagliardi Mick , Rousch Mat , Wijnands Erwin , Stoll Monika , Li Xiaofei , Schurgers Leon , Reutelingsperger Chris , Schalkwijk Casper , van den Akker Nynke M. S. , Molin Daniel G.M. , Gullestad Lars , Eritsland Jan , Hoffman Pavel , Skjelland Mona , Andersen Geir Ø. , Aukrust Pål , Karel Joël , Smirnov Evgueni , Halvorsen Bente , Temmerman Lieve , Biessen Erik A.L. 
Published: December 2022

AbstractAcute myocardial infarction (AMI) is accompanied by a systemic trauma response that impacts the whole body, including blood. This study addresses whether macrophages, key players in trauma repair, sense and respond to these changes. For this, healthy human monocyte‐derived macrophages are exposed to 20% human AMI (n = 50) or control (n = 20) serum and analyzed by transcriptional and multiparameter functional screening followed by network‐guided data interpretation and drug repurposing. Results are validated in an independent cohort at functional level (n = 47 AMI, n = 25 control) and in a public dataset. AMI serum exposure results in an overt AMI signature, enriched in debris cleaning, mitosis, and immune pathways. Moreover, gene networks associated with AMI and with poor clinical prognosis in AMI are identified. Network‐guided drug screening on the latter unveils prostaglandin E2 (PGE2) signaling as target for clinical intervention in detrimental macrophage imprinting during AMI trauma healing. The results demonstrate pronounced context‐induced macrophage reprogramming by the AMI systemic environment, to a degree decisive for patient prognosis. This offers new opportunities for targeted intervention and optimized cardiovascular disease risk management.
Topological Surface States in a Gyroid Acoustic Crystal
Authors: Guo Yuning , Rosa Matheus I. N. , Ruzzene Massimo 
Published: December 2022

AbstractThe acoustic properties of an acoustic crystal consisting of acoustic channels designed according to the gyroid minimal surface embedded in a 3D rigid material are investigated. The resulting gyroid acoustic crystal is characterized by a spin‐1 Weyl and a charge‐2 Dirac degenerate points that are enforced by its nonsymmorphic symmetry. The gyroid geometry and its symmetries produce multi‐fold topological degeneracies that occur naturally without the need for ad hoc geometry designs. The non‐trivial topology of the acoustic dispersion produces chiral surface states with open arcs, which manifest themselves as waves whose propagation is highly directional and remains confined to the surfaces of a 3D material. Experiments on an additively manufactured sample validate the predictions of surface arc states and produce negative refraction of waves at the interface between adjoining surfaces. The topological surface states in a gyroid acoustic crystal shed light on nontrivial bulk and edge physics in symmetry‐based compact continuum materials, whose capabilities augment those observed in ad hoc designs. The continuous shape design of the considered acoustic channels and the ensuing anomalous acoustic performance suggest this class of phononic materials with semimetal‐like topology as effective building blocks for acoustic liners and load‐carrying structural components with sound proofing functionality.
Optimizing Li‐Excess Cation‐Disordered Rocksalt Cathode Design Through Partial Li Deficiency
Authors: Huang Liliang , Zhong Peichen , Ha Yang , Cai Zijian , Byeon Young‐Woon , Huang Tzu‐Yang , Sun Yingzhi , Xie Fengyu , Hau Han‐Ming , Kim Haegyeom , Balasubramanian Mahalingam , McCloskey Bryan D. , Yang Wanli , Ceder Gerbrand 
Published: December 2022

AbstractLi‐excess disordered rocksalts (DRXs) are emerging as promising cathode materials for Li‐ion batteries due to their ability to use earth‐abundant transition metals. In this work, a new strategy based on partial Li deficiency engineering is introduced to optimize the overall electrochemical performance of DRX cathodes. Specifically, by using Mn‐based DRX as a proof‐of‐concept, it is demonstrated that the introduction of cation vacancies during synthesis (e.g., Li1.3‐xMn2+0.4‐xMn3+xNb0.3O1.6F0.4, x = 0, 0.2, and 0.4) improves both the discharge capacity and rate performance due to the more favored short‐range order in the presence of Mn3+. Density functional theory calculations and Monte Carlo simulations, in combination with spectroscopic tools, reveal that introducing 10% vacancies (Li1.1Mn2+0.2Mn3+0.2Nb0.3O1.6F0.4) enables both Mn2+/Mn3+ redox and excellent Li percolation. However, a more aggressive vacancy doping (e.g., 20% vacancies in Li0.9Mn3+0.4Nb0.3O1.6F0.4) impairs performance because it induces phase separation between an Mn‐rich and a Li‐rich phase.
Achieving a Large Driving Force on Triboelectric Nanogenerator by Wave‐Driven Linkage Mechanism for Harvesting Blue Energy toward Marine Environment Monitoring
Authors: Han Jiajia , Liu Yuan , Feng Yawei , Jiang Tao , Wang Zhong Lin 
Published: December 2022

AbstractWater wave energy is regarded to be a promising renewable energy source to relieve the pressure of fossil energy shortage and achieve a sustainable future. A cylindrical wave‐driven linkage mechanism triboelectric nanogenerator (WLM‐TENG) with unidirectional rotation is designed and fabricated to effectively harvest water wave energy. The enormous force generated by water waves, which is up to 424.3 N m−2, is used to drive the TENG through its simple and smart mechanical structure. This force allows the rotor to overcome the large resistance caused by the full contact between rabbit furs and electrodes. The output current can reach about 30 µA and the output power arrives at 50 mW. Moreover, self‐powered applications powered by the WLM‐TENG are successfully demonstrated, including indicating light‐emitting diodes (LEDs), multifunctional barometer, portable anemometer, and multifunctional water quality detection pen. This work renders an effective approach to harness the enormous force generated by the water waves, enhancing the water wave energy harvesting ability of the TENG, toward practical applications of marine environment monitoring.
Enhanced Ion/Electron Migration and Sodium Storage Driven by Different MoS2‐ZnIn2S4 Heterointerfaces
Authors: Cheng Jingyun , Niu Zhulin , Zhao Zhipeng , Pei Xiangdong , Zhang Shuo , Wang Hongqiang , Li Dan , Guo Zaiping 
Published: December 2022

AbstractConstructing hierarchical structures with heterointerfaces is an effective approach for developing high‐efficiency energy‐storage anodes for sodium‐ion batteries. In this study, MoS2@ZnIn2S4 nanorods are designed and fabricated for structural improvement. Theoretical calculations reveal that there are two different MoS2‐ZnIn2S4 heterointerfaces formed by MoS2 with the Zn and In facets of ZnIn2S4, which generate directional built‐in electric fields that provide additional driving forces for facilitating electron transfer. These two heterojunction interfaces, especially the MoS2‐In facet, exhibit enhanced Na+ adsorption energies and reduce Na+ diffusion energy barriers. The multistep reactions of MoS2 and ZnIn2S4 reveal a synergistic effect that promotes the entire electrochemical process. Furthermore, the synthesized hierarchical nanorods composed of nanosheets offer abundant Na+‐storage sites and multidirectional migration pathways and, importantly, accommodate the excessive volume change. Benefiting from the heterointerfaces and hierarchical structure, the composite electrode exhibits excellent electrochemical performance, with high reaction activity and rapid electron/ion diffusion kinetics.
Promoting Oxygen Reduction Reaction on Atomically Dispersed Fe Sites via Establishing Hydrogen Bonding with the Neighboring P Atoms
Authors: Zong Lingbo , Fan Kaicai , Li Ping , Lu Fenghong , Li Bin , Wang Lei 
Published: December 2022

AbstractSingle atom catalysts (SACs) comprised of nitrogen‐coordinated transition metal (TM–N–C) moieties show encouraging performance towards the oxygen reduction reaction (ORR). Nevertheless, for the reactions involving multiple intermediates, single‐atom sites fail to satisfactorily optimize the adsorption of all intermediates. Here, a facile strategy is reported to construct Fe, P dual‐atom sites in multimodal porous carbon (Fe,P‐DAS@MPC), and its superiority in synergistically boosting ORR is demonstrated. Fe,P‐DAS@MPC exhibits excellent ORR performance with substantially positive onset potential (Eonset = 1.02 V) and half‐wave potential (E1/2 = 0.92 V). Theoretical analysis unveils the cooperative effect of dual‐atom sites composed of adjacent P and Fe atoms, and the aiding of hydrogen bonding interaction can promote the adsorption/desorption of intermediates. Additionally, a Zn–air battery based on the Fe,P‐DAS@MPC shows a high peak power density and exceptional cycling stability. These findings provide a novel avenue towards the design of electrocatalysts with dual‐atom sites for practical energy conversion applications.
Nature and characteristics of gas–liquid flow regimes in a micro‐packed bed reactor
Authors: Liu Wei , Xie Bingqi , Zhang Chenghao , Duan Xiaonan , Zhang Jisong 
Published: December 2022

AbstractMicro‐packed bed reactors (μPBRs) have the advantages of high heat and mass transfer efficiency and excellent safety, and they have been successfully applied to hydrogenation and oxidation reactions. However, the study of gas–liquid flow regimes in the μPBR, which is essential for the mass transfer modeling and reactor scale‐up, is still insufficient due to the limitation of micro‐scale and complexity of capillary force. In this work, the flow regimes in the two‐dimensional μPBR were systematically studied by visual method utilizing a high‐performance camera. Four typical flow regimes and characteristics were captured, and flow regime transition was revealed. Effects of gas and liquid superficial velocities, liquid physical properties, and particle sizes on liquid spreading areal fraction and pressure drop were investigated. Flow regime transition correlation of churn flow and pseudo‐static flow in the μPBR was provided for the first time based on the summary of the current and previous published results.
Gas pressure intensifying oxygen transfer to significantly improving the bio‐oxidation productivity of whole‐cell catalysis
Authors: Hua Xia , Han Jian , Zhou Xin , Xu Yong 
Published: December 2022

AbstractOxygen, as a terminal electron acceptor, is an essential substrate in the aerobic bio‐oxidation process, affecting bacterial vitality and bio‐oxidation performance. In this study, a newfangled platform biotechnology of sealed‐oxygen supply bioreactor (SOS‐BR) was developed by improving gas pressure to significantly intensify oxygen transfer rate to resolve the formidable barriers of aerobic catalysis. In virtue of SOS‐BR, the bio‐productivity was greatly improved for three representative substrates (xylose, furfural, and glycerol) bio‐oxidation with the whole‐cell catalysis of Gluconobacter oxydans. The determination of oxygen transfer coefficient (KLα) established an upgraded theoretical dynamic model for gas pressure intensification biosystem. Additionally, viscosity measurement and combined pressure control strategy explained the inflection point phenomenon of productivity and confirmed the intensify mechanism. The smart strategy of significantly intensifying oxygen transfer provided insightful ideas for overcoming the stubborn obstacle of obligate aerobic catalysis, and further promoted the development and industrial practicability of bio‐oxidation.
Synthesis of Ni‐Al layered double hydroxide via coprecipitation: Formation mechanism, synthesis intensification, and catalytic application
Authors: Li Ying‐Jiao , Xue Lin‐Di , Zhang Yi‐Dong , Zhang Liang‐Liang , Chu Guang‐Wen , Sun Bao‐Chang , Chen Jian‐Feng 
Published: December 2022

AbstractHerein, the formation mechanism of Ni‐Al layered double hydroxide (NiAl‐LDH) synthesized by coprecipitation was explored. Moreover, NiAl‐LDH was prepared in a rotating packed bed (RPB) under different rotation speeds, which shows that increasing the rotation speed decreases the lateral size and thickness of NiAl‐LDH, since high rotation speed accelerates the nucleation of NiAl‐LDH. Additionally, the Ni/mixed metal oxides (MMO) catalysts derived from NiAl‐LDH were prepared for maleic anhydride (MA) hydrogenation. Result shows that Ni/MMO catalyst obtained from NiAl‐LDH prepared under a higher rotation speed exhibits higher MA conversion due to its larger surface area and smaller nickel particle size. The Ni/MMO catalyst obtained from NiAl‐LDH prepared under 500 rpm exhibits 100% MA conversion and 100% succinic anhydride selectivity under 30°C and 2 MPa within 1 h. This work provides fundamental insight to understand the formation of NiAl‐LDH. Moreover, RPB as an effective technique to synthesize NiAl‐LDH and Ni‐based catalysts was validated.
Nine years of the Red Book Challenge conservation education in Southern Madagascar: What we have learned
Authors: Walker‐Bolton Amber D. 
Published: December 2022

AbstractRed Book Challenge Conservation Education Madagascar is a small‐scale, arts‐based, conservation education initiative founded in 2012 by two Lemur catta researchers working in the Berenty Reserve and incorporated as a nonprofit organization in 2022. The target demographic is children and adults living in Southern Madagascar. The Red Book Challenge program initially consisted of providing supplementary conservation education through classroom visits at the elementary schools in Berenty village. The school children created small conservation booklets with red covers, giving the project its name. Today, the program has expanded to include the village of Besakoa Ambany and the city of Fort Dauphin, while remaining a small‐scale program. To date, the Red Book Challenge has completed seven outreach projects aimed at generating goodwill in the local community, community development, and conservation education. This retrospective analysis functions as a formative evaluation of the feasibility of future projects. This paper will focus on four projects that fall under the category of conservation education: (1) Using films to promote conservation topics (2) field trips to observe lemurs (3) a Malagasy‐run conservation club, and (4) a coloring book. These projects have been funded through small grants from the International Conservation Fund of Canada, and private donations. This paper includes the Red Book Challenge's history, results from the participant surveys, and the successes and failures in each stage of our work. Six shifts in thinking occurred: (1) use of Malagasy talent to create educational conservation films (2) more formal assessment before and after field trips (3) improvement of recruitment, training and supervision of staff to keep the conservation club self‐sufficient (4) enlistment of Malagasy illustrators and adaptation of environmentally friendly printing practices for the coloring books (5) disseminate study outcomes to international community though publication (6) reframe the program from spare‐time volunteer work to full‐time research work.
Anomalously Large Antiphase Signals from Hyperpolarized Orthohydrogen Using a MOF‐Based SABRE Catalyst
Authors: Alam Md Shahabuddin , Li Xinlin , Brittin Drew O. , Islam Saiful , Deria Pravas , Chekmenev Eduard Y. , Goodson Boyd M. 
Published: December 2022

AbstractHyperpolarized orthohydrogen (o‐H2) is a frequent product of parahydrogen‐based hyperpolarization approaches like signal amplification by reversible exchange (SABRE), where the hyperpolarized o‐H2 signal is usually absorptive. We describe a novel manifestation of this effect wherein large antiphase o‐H2 signals are observed, with 1H enhancements up to ≈500‐fold (effective polarization PH≈1.6 %). This anomalous effect is attained only when using an intact heterogeneous catalyst constructed using a metal–organic framework (MOF) and is qualitatively independent of substrate nature. This seemingly paradoxical observation is analogous to the “partial negative line” (PNL) effect recently explained in the context of Parahydrogen Induced Polarization (PHIP) by Ivanov and co‐workers. The two‐spin order of the o‐H2 resonance is manifested by a two‐fold higher Rabi frequency, and the lifetime of the antiphase HP o‐H2 resonance is extended by several‐fold.
Heparin desensitisation prior to cardiopulmonary bypass in a patient with alpha‐gal allergy
Authors: McRae A. S. , Tidwell W. P. , Patel S. , Lombard F. W. 
Published: December 2022

SummaryThis case report describes the implementation of a heparin desensitisation strategy for a patient with confirmed galactose‐alpha‐1,3‐galactose (alpha‐gal) allergy, prior to cardiac surgery. We describe the pre‐, intra‐ and postoperative management. We believe this report can enhance the limited data currently in existence on alternative strategies for heparin utilisation in cardiopulmonary bypass in a previously intolerant patient population.
SmartImage: A Machine Learning Method for Nanopore Identifying Chemical Modifications on RNA
Authors: Li Shijia , Li Xinyi , Wan Yong‐Jing , Ying Yi‐Lun , Yu Ru‐Jia , Long Yi‐Tao 
Published: December 2022

AbstractRNA modifications modulate essential cellular functions. However, it is challenging to quantitatively identify the differences in RNA modifications. To further improve the single‐molecule sensing ability of nanopores, we propose a machine‐learning algorithm called SmartImage for identifying and classifying nanopore electrochemical signals based on a combination of improved graph conversion methods and deep neural networks. SmartImage is effective for nearly all ranges of signal duration, which breaks the limitation of the current nanopore algorithm. The overall accuracy (OA) of our proposed recognition strategy exceeded 90% for identifying three types of RNAs. Prediction experiments show that the SmartImage owns the ability to recognize one modified RNA molecule from 1000 normal RNAs with OA >90%. Thus our proposed model and algorithm hold the potential application in clinical applications.
Design and Synthesis of Benzoheterodiazole‐based Fluorescent Compounds for Emitting Applications
Authors: Wang Zhichao , Wu Xu , Li Hanjie , Yu Jinghan , Wang Yanguang , Lu Ping 
Published: December 2022

AbstractBenzoheterodiazole‐based fluorophores with aggregation‐induced emission (AIE) properties are synthesized and their photophysical properties in different states (solution, film, and powder) are investigated. These compounds present excellent thermal stability, and the decomposition temperature is above 300 °C. Among these compounds, the fluorophores with triphenylamine (TPA) group present better fluorescent emissions in solutions as well as in aggregated states, and the highest solution fluorescent efficiency is up to 75.2% in solution. Meanwhile, the fluorescent compounds terminated with triphenylethene (TPE) exhibit the classical AIE properties. Furthermore, these compounds might be used as emissive layers for the fabrication of red, orange and green organic light emitting diodes.
Effects of a non‐universal IMF and binary parameter correlations on compact binary mergers
Authors: de Sá Lucas M. , Bernardo Antônio , Bachega Riis R. A. , Rocha Livia S. , Horvath Jorge E. 
Published: December 2022

AbstractBinary population synthesis provides a direct way of studying the effects of different choices of binary evolution models and initial parameter distributions on present‐day compact binary merger populations, which can then be compared to empirical properties such as observed merger rates. Samples of zero‐age main sequence binaries to be evolved by such codes are typically generated from a universal initial mass function (IMF) and simple, uniform, distributions for orbital period P, mass ratio q, and eccentricity e. More recently, however, mounting observational evidence has suggested the non‐universality of the IMF and the existence of correlations between binary parameters. In this study, we implement a metallicity‐ and redshift‐dependent IMF alongside correlated distributions for P, q, and e to generate representative populations of binaries at varying redshifts, which are then evolved with the COMPAS code in order to study the variations in merger rates and overall population properties.
Impact of pelvicalyceal anatomical variation on surgical outcomes of endoscopic combined intrarenal surgery
Authors: Kawase Kengo , Hamamoto Shuzo , Taguchi Kazumi , Inoue Takaaki , Okada Shinsuke , Sugino Teruaki , Isogai Masahiko , Torii Koei , Yanase Takahiro , Okada Tomoki , Hattori Tatsuya , Chaya Ryosuke , Okada Atsushi , Yasui Takahiro ,   the SMART Study Group
Published: December 2022

AbstractObjectivesThe objective of this work is to investigate the impact of the pelvicalyceal anatomical system (PCS) on calyceal stone formation and surgical outcomes of endoscopic combined intrarenal surgery (ECIRS) for renal and/or proximal ureteral stones with a diameter >15 mm.Patients and methodsPCS was classified as Type I (single pelvis) or Type II (divided pelvis) according to the simple anatomical Takazawa classification. Using prospectively collected data from January 2016 to April 2020, 219 patients were retrospectively reviewed. After excluding patients who underwent a staged procedure, had hydronephrosis greater than grade 2, prior nephrostomy tubes, and failed to access the renal collecting system, 115 patients (Type I: 81, Type II: 34) were included, and the distribution of calyceal stones and surgical outcomes in ECIRS were compared between Types I and II PCS.ResultsThe median number of renal stone calyces in the Type II group was significantly more than that in the Type I group (p = 0.016). In particular, the Type II group possessed more upper stone calyces. Multivariate logistic regression analysis revealed that Type II PCS was associated with an increased odds ratio (OR) for the presence of upper stone calyces (OR: 2.93, p = 0.018). The stone‐free (SF) status at 1 month after surgery, confirmed by abdominal plain radiography, was significantly higher in the Type I group compared with that in Type II (67.9% vs. 39.4%, respectively; p = 0.006). The requirement for additional surgical interventions was significantly higher in the Type II group compared with that in Type I (35.4% vs. 7.4%, respectively; p < 0.001). Multivariate analysis revealed that the number of stone calyces (OR: 4.26; p = 0.001) and Type II PCS (OR: 3.43; p = 0.009) were independent predictors of residual stones after ECIRS.ConclusionWe first revealed that the anatomic properties of PCS play a role in both upper calyceal stone formation and in the success of the ECIRS procedure. Because the SF rate in Type II PCS was significantly lower than that in Type I PCS, additional percutaneous nephrolithotomy tracts might be required, even for ECIRS.
Erfahrungen beim Rückbau der Spannbetonbrücken am Neckartalübergang
Authors: Bicker Kurt 
Published: December 2022

AbstractDie Firma Max Wild ist spezialisiert auf den Rückbau von Brücken jeglicher Größe und Konstruktionsweise. In diesem Bericht werden anhand des Projekts Rückbau des Brückenzuges bei Heilbronn die Herangehensweisen vom Planungsentwurf bis zur Ausführung erläutert. Rückgebaut wird eine Spannbetonhohlkastenkonstruktion, die teilweise unterstützt und dann zersägt und ausgehoben wird. Zudem wird eine 585 m lange Vorlandbrücke, bestehend aus einem zweistegigen Plattenbalken, konventionell rückgebaut. Die 311,20 m lange Spannbetonbalkenbrücke mit bogenförmigen Hohlkästen wird sprengtechnisch zu Fall gebracht und im Anschluss konventionell zerkleinert und verwertet.