bluuebunny/crossref_metadata_2025_split huggingface dataset:
Robot-assisted mobilisation in the intensive care unit - does it offer relief to mobilising specialists? A qualitative longitudinal study at three data collection points at a German university hospital
Authors: Mehler-Klamt Amrei Christin , Huber Jana , Köstler Natascha , Warmbein Angelika , Rathgeber Ivanka , Fischer Uli , Eberl Inge 
Published: August 2023

Abstract

Intensive-care patients are often forced into extended immobility, bringing with it a high risk of long-term damage. Reasons for this include the shortage of specialist staff in healthcare, lack of aids and the high safety risk involved in transferring patients to a therapy device. However, early mobilisation can positively affect patient outcome and counteract complications. Robotic systems may also help relieve mobilising staff and make mobilisation more feasible. A qualitative longitudinal study was performed to investigate how mobilising specialists perceive the use of a robotic system for mobilisation and which stress and relief factors occur in this context. A total of 29 guided interviews were conducted at three data collection points for this. The evaluation was performed using qualitative content analysis.
Results show that mobilisation using the robotic VEMOTION® system was perceived as less physically stressful or physically relieving when compared to conventional mobilisation. The psychological stress was higher than the psychological stress during conventional mobilisation (T1), in particular in the non-routine users (T2) of robot-assisted mobilisation. The greatest challenges were the high time requirements for preparation as well as the integration of mobilisation into the daily routine. The lack of routine and the associated uncertainty in dealing with the system were named as a major problem. These aspects meant that some users who hadn`t yet been able to develop a routine (T2) with the device didn`t accept the system and didn`t use it as a result. Users with routine (T3) described robot-assisted mobilisation as causing little psychological stress.
Trial registration:clinicaltrials.org TRN: NCT05071248, Date: 2021/10/21 URL: https://clinicaltrials.gov/ct2/show/NCT05071248
A Case of Anti-IgLON5 Disease with Aplastic Anemia and review of the literature
Authors: Tafakhori Abbas , Ebadi Seyyed Reza , Amirifard Hamed , Karima Saeed , Amani Kiana , Hasani Arian , Esmaeili Nazanin 
Published: August 2023

Abstract
BACKGROUND: The Anti-IgLON5 disease was first described as an abnormal neurological condition explained by a dual etiology hypothesis of neurodegeneration and autoimmunity.
CASE: A 64-year-old man with a 2-year history of aplastic anemia presented with neurological symptoms and signs including symmetrical parkinsonism, fluctuation in consciousness, supranuclear gaze palsy, mild fasciculation, and muscular atrophy. Three months earlier, he was referred to a sleep clinic, and polysomnography (PSG) revealed a sleep efficiency of 63.6%, increased sleep stages 1 and 2, and the absence of N3 stage or REM sleep. Brain MRI showed extensive cortical atrophy with significant Virchow-Robin spaces. CSF analysis was unremarkable, except a positive test result was achieved later for the IgLON5 antibody. Immunotherapy was initiated with high-dose methylprednisolone and intravenous immunoglobulin followed by treatment with rituximab. A mild to moderate response to treatment was observed in this case.
REVIEW OF THE LITERTURE: In this study we reviewed 29 published case reports about anti-Iglon 5 and examined all of the clinical manifestations that patients experienced with detail. None of the cases showed aplastic anemia, which was the main finding in our case. All of the patients experienced sleep disturbances in the course of their disease, but other symptoms were heterogeneous.
CONCLUSION: Correlation of cognitive symptoms in the absence of sleep disturbances at the beginning of the course of the anti-IgLON5 disease may lead to a late diagnosis and a worse prognosis. This study also had a unique impression on available documents, which could cause further changes to the notion of an association between other autoimmune disorders, such as anemia in this case and anti-IgLON5 disease.
The work-lives of Canadian Registered Dietitians during the COVID-19 pandemic: a descriptive analysis of survey data
Authors: Hewko Sarah Jean , Freeburn Julia 
Published: August 2023

Abstract
Background
Healthcare workers experienced significant disruptions to both their personal and professional lives throughout the COVID-19 pandemic. How health providers were impacted varied, depending on area of specialization, work setting, and other factors. Dietetics is a female-dominated profession and the differential impact on women of the COVID-19 pandemic has been widely reported. While researchers have explored RDs’ experiences during the pandemic, none have looked explicitly at their experiences of redeployment. The objectives of this study were to better understand: i) the impact of COVID-19 (and related redeployments) on the work-lives of Registered Dietitians (RDs), ii) what types of COVID-19 related supports and training were made available to these RDs, and iii) the impact of RD redeployment on access to RD services.
Methods
An online survey was administered in June 2022. Any RD that that was publicly-employed in Canada during the pandemic was eligible to participate. The survey included questions related to respondent demographics, professional details, redeployment and training. We conducted descriptive analyses on the quantitative data.
Results
The survey was completed by 205 eligible RDs. There were notable differences between public health and clinical RDs’ redeployment experiences. Only 14% of clinical RDs had been redeployed, compared to 88% of public health RDs. Public health RDs were redeployed for longer and were more likely to be redeployed to roles that did not required RD-specific knowledge or skills. The most commonly reported mandatory training was for proper use of PPE. The most commonly reported reasons for a lengthy absence from work were anxiety about contracting COVID-19, school closures and limited child care availability.
Conclusions
Public health RDs are at the forefront of campaigns to reduce the burden of chronic disease, improve health equity and enhance the sustainability of food systems. Close to 90% of these RDs were redeployed, with many seeing their typical work undone for many months. More research is needed to quantify the consequences of going without a public health nutrition workforce for an extended period of time and to understand the differential impact gender may have had on work experiences during the pandemic.
Is there A Link between vaginal relaxation syndrome and pelvic tilt?
Authors: Hady Doaa Abdel 
Published: August 2023

Abstract
Introduction: Vaginal relaxation syndrome (Vaginal laxity) is feeling of excessive vaginal looseness; it is one of the most common symptoms of pelvic floor dysfunction (PFD). This study to determine is there a link between vaginal relaxation syndrome and pelvic tilt in multiparous women with vaginal laxity. Methods: An observational, cross-sectional study, the study included 100 women who were divided into two groups based on their vaginal laxity questionnaire (VLQ) results. The vaginal laxity group included 50 women, whereas the control group included 50 women who did not have vaginal laxity. The Female Sexual Function Index (FSFI) was used to assess sexual function, and ultrasound imaging was employed to measure pelvic floor muscle force and pelvic tilt in both groups. The Arabic version of the female sexual function index (FSFI) was used to assess sexual function, and ultrasound imaging was used to measure pelvic floor muscle force and pelvic tilt using a spinal mouse device. Results: There was a significant increase in PFM force and FSFI of group B compared with that of group A (p < 0.01), There was a significant increase in pelvic tilt of group A compared with that of group B (p < 0.001), There was a significant increase VLQ of group B compared with that of group A (p < 0.001) . Conclusion: Vaginal laxity negatively affected women's sexual function & PFMs strength& force and pelvic tilt. Implications of physiotherapy practice: Our finding may help in a physical therapy plan for the treatment of vaginal relaxation syndrome. Most physical therapy programs for vaginal relaxation tend to concentrate solely on the PFMs, disregarding training for pelvic tilt. Women who have vaginal relaxation syndrome and nonspecific low back pain may have pelvic tilt.
Accuracy and adequacy of photoprotection in pediatric systemic lupus erythematosus patients, and the effect of education on photoprotection: a prospective study
Authors: Suebsarakam Porntipa , Mairiang Dara 
Published: August 2023

Abstract
Background:
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that is associated with multiple organ involvement and leads to significant morbidity and mortality. One of the important environmental factors that influences the exacerbation of preexisting SLE is ultraviolet (UV) radiation, so photoprotection is essential. The aims of this study were to evaluate the accuracy and adequacy of photoprotection in pediatric SLE patients, and to investigate the effect of education on photoprotection.
Methods:
SLE patients aged ≤ 18 years who attended pediatric outpatient clinics were prospectively enrolled. The accuracy and adequacy of photoprotection were assessed by the questionnaire, and compared between baseline and the ≥3-month follow-up timepoint. Comprehensive written and verbal photoprotection education was provided to all patients and parents/caregivers after the first assessment.
Results:
One hundred patients were included (mean age 13.6 ±2.5, 92% female). At the first assessment, 79% of patients used sunscreen with a sunburn protection factor ≥ 30 (77%) and protection grade of ultraviolet A +++ (63%). Fifty-two percent of patients applied sunscreen every day. A minority of patients applied an adequate amount of sunscreen (32%), used water-resistant sunscreen (34%), used lip balm with sunscreen (23%) and reapplied sunscreen when sweating (13%). The most commonly missed areas when applying sunscreen were the ears and dorsum of the feet. The least often practiced sun protection behavior was wearing sunglasses. The most often reported activities during the peak UV index, were playing with friends and walking to the cafeterias. At the second assessment, the majority of photoprotection practices were improved in all aspects except using water-resistant sunscreen, reapplying sunscreen when sweating, applying sunscreen on the ears and dorsum of feet, and wearing sunglasses. The main reason for not using sunscreen switched from thinking it was unnecessary at the first assessment to disliking its texture at the second assessment.
Conclusions.
The photoprotection practices that need to be specifically emphasized are applying an adequate amount of sunscreen, reapplying sunscreen when sweating, applying sunscreen on the ears and dorsum of the feet and wearing sunglasses. Education on photoprotection was effective.
Uncovering Evidence to Migrate from Face-to-Face to the Blended Learning Classroom
Authors: Schonwetter Dieter , Yerex Katherine , Monin Caroline 
Published: August 2023

Abstract

Introduction/Aims:The focus of the present study was to explore the impact of the traditional lecture compared to online teaching, given the critical need during the COVID pandemic. We considered the learning preferences of students and measured their achievement using both hard and soft metrics.Design/Setting:First-year dental hygiene and dentistry students were randomly assigned to one of two teaching conditions (Lecture, Online). Material/Methods: Baseline measures of achievement of the content, along with Edmond’s learning styles and comfort level learning in online and lecture conditions, were assessed. Students completed post-lecture assessments immediately after the lecture and again six months later.Results/Discussions:Regardless of the teaching condition, students showed significant improvement in their academic performance compared to the baseline measures. Their learning preferences were found to be linked with higher engagement levels, a sense of accomplishment, and control over their learning environment.Conclusions:Teaching health sciences students can be challenging, particularly when moving from traditional face-to-face in-person classes to online learning. It’s essential to accommodate and support various learning styles to make the most of using technology in education, leading to improved learning outcomes for students.
Network pharmacology-based anti-colorectal cancer activity of piperlonguminine in the ethanolic root extract of Piper longum L.
Authors: Singh Indrajeet , Das Richa , Kumar Ajay 
Published: August 2023

Abstract
The most frequent cancer to affect the human colon is colorectal cancer (CRC). CRC has the second highest incidence and fatality rates of any malignancy, at 10.2 and 9.2 percent, respectively. Plants and plants-based products for thousands of years, have been utilized to treat cancer along with other associated health issues. Alkaloids are a valuable class of chemical compounds with great potential as new medicine possibilities. Many of the alkaloids tested from different types of medicinal plants and herbs were found to impede proliferation of cells and kill many types of cancer cells. Piper longum Linn contains various types of alkaloids. In this research, the ethanolic root extract of Piper longum (EREPL) is the subject of study based on network pharmacology. Two alkaloids were picked from the gas chromatography mass spectrometry (GC-MS) analysis. However, only piperlonguminine received preference because it adhered to Lipinski's rule and depicted no toxicity. Web tools which are available online, like, Swiss ADME, pkCSMand ProTox-II were used to evaluate the pharmacokinetics and physiochemical properties of piperlonguminine. The database that SwissTargetPrediction and TCMSP maintain contains the targets for piperlonguminine. Using DisGeNET, GeneCards and Open Targets Platform databases, we were able to identify targets of CRC. The top four hub genes identified by Cytoscape are SRC, MTOR, EZH2, and MAPK3.The participation of hub genes in colorectal cancer-related pathways was examined using the Kyoto Encyclopaedia of Genes and Genomes (KEGG) database. The colorectal cancer pathway, the ErbB signaling pathway and the mTOR signaling pathway emerged to be important. Our findings show that the hub genes are involved in the aforementioned pathways for tumor growth, which calls for their downregulation. Additionally, piperlonguminine has the potential to become a successful medicine in the future for the treatment of CRC.
Increasing precipitation deteriorates the progress of pesticide reduction policy: a case study in the Yellow River
Authors: Ouyang Wei , Guo Zewei , Chen Ming , Tulcan Roberto Supe , Lin Chunye , He Mengchang 
Published: August 2023

Abstract
Precipitation variation profoundly affects agricultural development and increases the diffuse pollution risk, which may weaken the positive effects of pesticide reduction policy. This study aimed to analyze the response of pesticide discharge loads in the largest vulnerable watershed to pesticide application intensity and precipitation variance before and after implementing the pesticide reduction policy. We integrated empirical models, field observation and statistics to explore the sensitive factors of the typical pesticide atrazine before and after the pesticide reduction policy in the Yellow River Watershed. The results showed that the implementation of pesticide reduction policy effectively decreased the discharge load of atrazine within the watershed annually. In addition, the most sensitive factor of atrazine discharge loads shifted from precipitation to the atrazine application intensity after implementing the pesticide reduction policy. However, the discharge loads of atrazine significantly increased in an unusual high precipitation year after implementing the pesticide reduction policy.
Three-year clinical performance of direct Restorations using Low Shrinkage Giomer versus Nanohybrid Resin Composite
Authors: Toz-Akalin Tugba , Öztürk-Bozkurt Funda , Kusdemir Mahmut , Özsoy Alev , Yüzbaşıoğlu Emir , Özcan Mutlu 
Published: August 2023

Abstract
Objectives
The objective of this investigation was to compare the clinical performances of nanohybrid and low-shrinkage bioactive resin composites.
Materials and methods
Totally, 35 pairs of restorations performed with either low-shrinkage bioactive Giomer (Beautifil II LS, Shofu Inc.) or nanohybrid (Clearfil Majesty Posterior) resin composites in 35 patients by two operators using the relevant adhesives: FL-Bond II (Shofu Inc) and Clearfil SE Bond (Kuraray), according to each manufacturer’s instructions. Two clinicians assessed the restorations two weeks after restorative procedures (baseline), after six months, one, two and three years using FDI criteria (Scores 1–5). Data were analyzed using the marginal homogeneity and the McNemar test. Survival Rate was calculated using Kaplan-Meier survival analysis and the survival of the two groups was compared with the Log-Rank test (p = 0.05).
Results
Mean observation period was 37.7 ± 6.8 months. All restorations completed their 3-years follow up. All criteria were rated mainly with high (1 or 2) scores for quality in both groups. Only one restoration from low-shrinkage Giomer restorative group was accepted as failure due to retention loss of the restorative.
Conclusion
Over the three-year follow-up, both the Giomer and the nanohybrid resin composite restorations’ performances were similar and clinically acceptable.
Clinical relevance
Low-shrinkage bioactive material Giomer resin composite exhibited similar clinical performance to the nanohybrid resin composite after three years in service, with both materials displaying minor surface deteriorations at three-year recall.
Trial registration
Clinical Trial Registration Number: NCT02823769.
Thumbnail-preserving encryption by sum-preserving within blocks based on exponential chaotic mapping
Authors: Liu Lingfeng 
Published: August 2023

Abstract
In recent years, chaotic sequences have been widely used in image encryption. Wuqi proposed a new rule which one-dimensional discrete chaotic mapping should follow, based on which a noval one-dimensional chaotic mapping was created from the definition of Lyapunov exponent (LE), and this chaotic mapping was combined with a three-pixel thumbnail-preserved encryption (TPE). Diffrent from the existing TPE schemes, the scheme uses a three-pixel sum preserving encryption (SPE) scheme as an example and uses mathematical expressions to illustrate the encryption and decryption methods. The experimental results show that the proposed chaotic mapping has good chaotic properties. Based on this novel TPE scheme, the encrypted image has both high security and usability, which is also competitive with other schemes.
Specific functions of single pistil S-RNases in S-gene homozygous Pyrus germplasm
Authors: Qi Yongjie , Gao Zhenghui , Ma Na , Lu Liqing , Ke Fanjun , Zhang Shaoling , Xu Yiliu 
Published: August 2023

Abstract
Gametophytic self-incompatibility (SI) is regulated by S-allele recognition; that is, pollen in a style with the same S-genotype will undergo programmed cell death and stop growing so that it is unable to complete double fertilization, ultimately resulting in the SI response. S-RNase is the female determinant of SI in pear (Pyrus bretschneideri). In the Pyrus genome, there are two different S-RNase genes at the same S-locus, which generate two different S-RNase products in the pistil. The extracted S-glycoprotein is actually a protein complex. In this study, artificial self-pollination was conducted at the bud stage to overcome SI in ‘Huanghua’ (S1S2) pear. Seven plants homozygous for S1-RNase and four homozygous for S2-RNase were selected from the selfed progeny of ‘Huanghua’ by S-gene molecular identification biotechnology. We investigated the function of single S-RNases isolated from the pistils of S-gene homozygous Pyrus germplasm. The pollen of ‘Huanghua’ could smoothly pass through the style of the S-gene homozygous germplasm and complete fertilization. S-RNases were extracted from flower styles of different genotypes and used to treat different types of pollen. The S-RNase from ‘Huanghua’ completely inhibited the growth of S1S2,S1S1, and S2S2 pollen, while the S-RNase from homozygous germplasm allowed some S1S2 pollen and different single genotypes of pollen to continue growing. These results further validate the core events of SI including cytoskeleton depolymerization and programmed cell death. By iTRAQ-based proteomic analysis of style proteins, a total of 13 S-RNase-related proteins were identified. In summary, we have created reliable S-RNase gene homozygous germplasm, which will play a crucial role in further research on SI in pear and in the development of the pear industry.
Delay reduction in MTC via SDN based offloading in a Fog Computing environment with the assistance of volunteer nodes
Authors: Arefian Zahra , Khayyambashi Mohammad Reza , Movahhedinia naser 
Published: August 2023

Abstract
This article discusses the integration of Distributed Fog Computing (FC) and Software-Defined Networking (SDN) for efficient resource management in Machine Type Communications (MTC). FC brings Cloud resources closer to the user, enhancing service quality and reducing delays. Some MTC devices have powerful processors that can be used as volunteer nodes to process lightweight requests, thereby increasing the network's distributed processing capabilities. The paper proposes a framework that uses priority and differential flow space allocation to handle heterogeneous requests in MTC and assign delay-sensitive flows to priority queues on each Fog node. To address the limited resources available on individual Fog nodes, the article recommends offloading flows to other Fog nodes and volunteer nodes through a decision-based SDN controller. The article models flow-based Fog nodes using queueing theory, employing priority polling algorithms to service the flows and alleviate the issue of resource starvation in a multi-queueing environment. It is observed that the percentage of delay-sensitive processed flows, the network consumption, and the average service time in the proposed mechanism are improved by about85%, 68%, and 62%, respectively, compared to traditional Cloud computing. Therefore, the delay reductions based on the types of flows and task offloading is proposed.