bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ecological Damage Behind Ski Resorts and Feasible Governance Measures
Authors: Bao Chongchao 
Published: July 2023

Construction of ski resorts involves machine-grading slopes, which alters the soil's physical, chemical, and biological qualities and has a substantial long-term ecological influence on the environment. To improve slope stability and reduce the risk of natural hazards and restore the biotic and abiotic conditions of the soil, it is important to establish and develop plant communities. This study assesses changes in plant-soil characteristics and the long-term consequences of machine-grading and concurrent ski-run restoration to help create the best procedures for future ski-run development. Ski trails were surveyed for soil, vegetation and root characteristics and unaltered control sites away from the ski trails were evaluated. Plant cover on ski trails remained constant over time, but plant richness and variety significantly increased, reaching levels comparable to undisturbed vegetation. The plant mix transitioned to more semi-natural stages, exhibiting decreased planted plants and a corresponding rise in the cover of native species populating the area. Compared to unaffected locations, the root trait data showed significant differences between machine grading and vegetation’s short- and long-term effects. As a result of long-term management, the aggregate stability in the ski slopes remained lower as well as the organic content remained higher than in the undisturbed locations. Even though the soil still has a lower chemical and physical fertility than the quiet sites, the plant species composition indicates a satisfactory degree of renaturalization. The standard actions used allowed the ecosystem to recover in three decades partially.
Determination of Physiological, Biochemical and Anti-oxidative Status in Type 1 Diabetes Mellitus Patients
Authors: Arsalan Hafiz Muhammad , Kousar Gulnaz , Akylbek Amanbekovich Amanbekov , Ashfaq Munib 
Published: July 2023

Type 1 Diabetes Mellitus (T1DM) disorganization of glucose equilibrium distinguishes by autoimmune disruption of the insulin producing pancreatic β-cell that constantly leads to insulin scarcity and resulting hyperglycemia Objective: To determine the physiological, biochemical, and anti-oxidant status in Type 1 Diabetes Mellitus Patients. Methods: It is a comparative study. 60 diabetic patients and 50 Samples of healthy individuals were taken from Nawaz Sharif Hospital. Blood samples (5.0 ml) were obtained and centrifuged at 4000 rpm for 10 minutes to separate the serum. Glutathione (GSH), Catalase (CAT), Superoxide Dismutase (SOD), Malondialdehyde (MDA), Nitric oxide (NO), micronutrients (Vitamin A, Vitamin C and Vitamin E) and Electrolytes was determined. Results: MDA level is progressively higher in T1DM (14.01±0.06) as compared to control group (1.27±0.21) (P- Value 0.000). GSH status is notably reduced in diabetic patients (0.15±.05) as compared to normal (6.24±0.33). Comparable anti-oxidant catalase is reduced (2.82±.04) in affected individuals as compared to normal individuals 4.19±1.09. SOD level was remarkably marked up to (13.52±3.21) in susceptible persons as compared to normal (2.15±0.23). Vitamin A level was markedly reduced to (1.62±0.26) in patients as compared to healthy individuals (7.18±0.33). Conclusions: T1DM patients particularly showed reduced amounts and competency of antioxidant protections due to elevated consumption of specific anti-oxidant components such as low level of intracellular glutathione and Catalase and primarily low levels of vitamin A, vitamin E and vitamin C and exalted level of MDA, SOD and NO.
Appendix The Ideological Drivers Behind the Support for the Use of Direct Democracy among Voters and Parties of Benelux Countries
Authors: Paulis Emilien , Rangoni Sacha 
Published: July 2023

The Ideological Drivers Behind the Support for the Use of Direct Democracy among Voters and Parties of Benelux Countries
The use of referendums has gained popularity among both voters and parties. Yet, despite the diffusion of such direct forms of democracy during the last decades in Europe, referendums remain not a very common policy instrument in Benelux countries (Belgium, the Netherlands and Luxembourg). We establish that this trend could be explained by a large consensus among mainstream (especially right) parties and voters against the use of direct democracy. Moreover, we confirmed the well-established demarcation with radical ideologies, which convey overall more support and congruence on the use of referendums than the mainstream. Additionally, and probably reflecting this new line of cleavage, we show that support for referendums among the voters relate to left-wing economic position, but also with culturally right-wing view. Overall, this article questions the relevance of the traditional left-right divide to explain support for direct democracy, as well as the capacity for (some) parties to align with their voters in terms of democratic demands.
Aplicação da acupuntura estética e da ventosaterapia no tratamento de rugas estáticas faciais
Authors: Leal Lázara Thalita Ferreira , Souza Geyse Kerolly Brasileiro Lima , Do Prado Débora Pereira Gomes , Bridi Vanessa , Ribeiro Isabella da Costa , Barbosa Isa Marianny Ferreira Nascimento , Rezende Stéfanne Rodrigues , Rezende Hanstter Hallison Alves 
Published: July 2023

Fornazieri, L.C. (2013). Tratado de Acupuntura Estética. 2a ed. São Paulo: Ícone.

Menoita, E.; Santos, V. & Santos, A.S. (2013). A pele na pessoa idosa. Journal of aging and innovation, v. 2.

Bragato, P. E.; et al. (2013) Aplicação de eletrolifting em rugas faciais: relato de caso. Revista UNIANDRADE, v. 14, n. 2.

Macedo, M. C. A. (2015). Tratamento de rugas: uma revisão bibliográfica sobre carboxiterapia, radiofrequência e microcorrente. Revista Visão Universitária, v.2, n. 1.

Nakano, M. A. Y.; Yamamura, Y. (2010). Livro dourado da acupuntura em dermatologia e estética. Center AO, 2a ed.

Cruz, F.L.S.; Pereira, L.P. (2018). Estética facial: acupuntura no tratamento de rugas. Revista Saúde em Foco. Edição nº 10. p. 181-185.

Ribeiro, H. R. (2021). A eficácia da acupuntura no tratamento e prevenção de rugas: revisão bibliográfica. Health of Humans, v.3, n.2, p.1-11. Fernandes 2008

Amaro, P. E. Q. (2015). Ventosaterapia no Tratamento de Acne Vulgar. 24 f. Trabalho de Conclusão de Curso (Pró-Reitoria de Graduação Curso de Biomedicina) , Universidade Católica de Brasília, Brasília-DF.

Ribeiro, J. C.; et al. (2019). Ventosaterapia: tratamento alternativo para diversas afecções. Revista Saúde em Foco, v. 1, n.11, p. 1381-1393.

Chirali, I. Z. Ventosaterapia: Medicina Tradicional Chinesa. Roca, 1a ed., 1997.

Rodrigues et al. (2022). Harmonização Orofacial no restabelecimento da autoestima: relato de caso. Aesthetic Orofacial Science, v. 3, n. 1, p. 19–28.

Fernandes, F. A. C. (2015). Acupuntura estética: prática e objetiva: novos procedimentos. 2a ed.,São Paulo: Ícone.

Skin Gym. Disponível em: <https://www.skingymco.com/pages/beauty-guides>. Acesso em: 20 jan 2023.

Neuwirth, A.; Chaves, A. L. R.; Bettega, J. M. R. (2010). Propriedades dos óleos essenciais de cipreste, lavanda e hortelãpimenta. UNIVALI. Santa Catarina.
Ross, J. (2003). Combinações dos pontos de acupuntura: a chave para o êxito clínico. São Paulo: Roca.

Truppel, A.; Marafon, H. C.; Valente, C. (2020). Argiloterapia: uma revisão de literatura sobre os constituintes e utilizações dos diferentes tipos de argila. Revista Faz Ciência, v. 22, n. 36, p. 143.
Can "resilience" protect key workers from poor mental health?
Authors: Anderson Gregory S , Carleton R. Nicholas 
Published: July 2023

Can “resilience” protect key workers from poor mental health?
First responders, other public safety personnel, and healthcare workers appear to be those most at risk of poor mental health following their occupations – but what does increasing resilience do, and how can governments protect their key workers? The contemporary Canadian healthcare model and associated research efforts typically focus on diagnoses and treatments of experienced illnesses and injuries; in contrast, proactive mitigation efforts have received much less attention.
Exploring neurological & mental brain disorders in Europe
Authors: Kramer Stephanie , Destrebecq Frédéric 
Published: July 2023

Exploring neurological & mental brain disorders in Europe
Stephanie Kramer and Frédéric Destrebecq of the European Brain Council discuss updates on Brain disorders in Europe – neurological and mental alike. Brain disorders are widespread in Europe, highly disabling and often difficult to treat. Approximately 60% of the European population lives with a neurological condition, and one in six citizens in Europe is affected by mental ill-health. To Kramer and Destrebecq, investing in the brain and brain research is critical. However, instead of divesting in a cost, policymakers and society at large should view the prioritisation and support of research into brain disorders as an investment into a healthier future. Calling for prioritisation of research of brain disorders at the political level has been a major effort from the brain research community for decades, but, despite a steady growth of investment by the European Union, it has been nowhere near enough, lacks efficiency, remains fragmented, lacks recognition as a priority area, and is persistently misunderstood and underestimated.
Keep your teeth for life, but how?
Authors: Christophel Ruth , Donnet Marcel , Dixit Neha 
Published: July 2023

Keep your teeth for life, but how?
Drs Marcel Donnet and Neha Dixit discuss the importance of teeth cleaning and how the innovative AIRFLOW® PLUS powder can tackle biofilm and safeguard oral health. Researchers have long discussed the importance of teeth cleaning and the link between a healthy mouth and providing a good foundation for a healthy body. Luckily, the association between oral and overall health is becoming increasingly well-known. Together with researchers and clinicians, EMS has developed Guided Biofilm Therapy (GBT) to completely remove plaque (also known as biofilm) and calculus. In eight steps, patients are diagnosed, motivated by disclosing and treated to a wellness-like experience. Here, Drs Donnet and Dixit look to the challenges associated with teeth cleaning, how dentists can remove biofilm, and whether powder have any negative impacts or damage the tooth surface or structure. Overall, they argue that from the patient’s point of view, their methods will provide the most comfortable, pain-free treatment option for effective teeth cleaning.
The rotating lepton model: Electron and positron catalysis of chemical and nuclear synthesis
Authors: Vayenas Constantinos G , Tsousis Dionysios 
Published: July 2023

The rotating lepton model: Electron and positron catalysis of chemical and nuclear synthesis
Professor Emeritus Constantinos Vayenas from the University of Patras and PhD student Dionysios Tsousis from Stanford University discuss electron and positron catalysis in the CERN e+e- annihilation experiments via the Rotating Lepton Model. Electrons and positrons play a central role in heterogeneous catalysis and electrochemistry since they can interact directly via electrostatic interactions with molecular or ionic reactants, intermediates, and products. Electrochemistry’s entire science and technology is based on electrostatic electron – or positron-atom interactions. Here, they discuss the elementary particles, microscopic reversibility and the Rotating Lepton Model, Experimental validations of the Rotating Lepton Model, neutrino rest masses computation, and finally, structural information. In summary, the CERN positron-electron annihilation experiments shed new light on the interactions between neutrinos, positrons and electrons and confirm the mechanism of the Rotating Lepton Model by showing that the Z boson is a rotating positron-electron-neutrino (m3) (e+e– ν3) particle.
The development of research software engineering as a profession
Authors: Leng Joanna 
Published: July 2023

The development of research software engineering as a profession
Dr Joanna Leng at the School of Computing explores Research Software Engineering (RSE) as an emerging profession, and how computing technology is core to many professions. Research Software Engineering is a young and emerging profession. This article looks at how it compares to other more mature professions and how all these professions handle two factors that are particularly important to the RSE profession, the stability of computing technologies and the adoption of these computing technologies by each profession.
The history of psychedelics and why psychedelic stories matter
Authors: Dyck Erika 
Published: July 2023

The history of psychedelics and why psychedelic stories matter
Erika Dyck argues that how people learn about psychedelics today matters, based on the histories of these drugs and how they have been and should be used in clinical medicine. While these substances have piqued the interest and influenced the attitudes of individuals across academia, culture, and medicine, expanding before and well after the 1950's, Dr. Dyck notes that psychedelic drugs have had a long and colourful history. However, their history has not come without polarising opinions, as until recently, trends in cultural attitudes towards non-medical drug use in general and the role of consciousness-altering substances in clinical medicine have often been negative. Despite this writing tradition, more and more public conversations on psychedelics are coming from people with enthusiastic claims about the benefits of psychedelic drug use that rely on severing the current culture of psychedelics from the past, and some might even suggest severing psychedelics from mainstream institutions which tend to be more conservative – like universities or food and drug administrations, or even healthcare systems.
Welfare economics: Promoting equality through general policies
Authors: Ng Yew-Kwang 
Published: July 2023

Welfare economics: Promoting equality through general policies
Yew-Kwang Ng, Emeritus Professor at the Department of Economics, Monash University, continues a discussion about welfare economics, focusing on efficiency supremacy in specific areas, arguing that equality should be promoted through general policies. In the April issue, I published a piece on ‘An Economic Analysis of Social Welfare’ and in an Open Access Government eBook, a piece on ‘The Welfare Foundation of Public Policies and Its Implications’. Here, and in subsequent pieces in October 2023, January and April 2024, I will discuss some important messages of welfare economics for public policies.
A focus on Global Biodiversity Framework Target 7: Approaches to pollution
Authors: Neumann Christoph 
Published: July 2023

A focus on Global Biodiversity Framework Target 7: Approaches to pollution
Dr Christoph Neumann analyses the Global Biodiversity Framework Target 7, and explains the need for a qualified risk-based approach to pollution from the COP15 convention. The key outcome of the COP15 Convention on Biological Diversity (CBD) meeting in December 2023 in Montreal was adopting the Global Biodiversity Framework. Target 7 of the Global Biodiversity Framework, as adopted, reads as follows: “Reduce pollution risks and the negative impact of pollution from all sources, by 2030, to levels that are not harmful to biodiversity and ecosystem functions and services, considering cumulative effects, including:” (a) “reducing excess nutrients lost to the environment by at least half including through more efficient nutrient cycling and use;” (b) “reducing the overall risk from pesticides and highly hazardous chemicals by at least half including through integrated pest management, based on science, taking into account food security and livelihoods; and also” (c) “preventing, reducing, and working towards eliminating plastic pollution.” (1)
Developing novel treatments for childhood solid cancers
Authors: Houghton Peter J 
Published: July 2023

Developing novel treatments for childhood solid cancers
With a particular focus on glioma, Dr Peter J Houghton from Greehey Children’s Cancer Research Institute outlines the barriers that have hindered the development of effective therapies for childhood solid cancers. Childhood cancer represents less than 1% of human cancers, thus, is not a priority for drug development in the pharmaceutical industry. However, the consequences of having a child diagnosed with a malignant disease can be devastating for families. Developing new therapies for childhood solid cancers presents certain constraints that are seldom encountered with neoplastic diseases diagnosed in adults. Childhood tumours are rare, which has therefore restricted large-scale drug evaluations or randomised clinical trials. For example, of the new Phase I agents evaluated in adult malignancies, less than 30% receive an adequate assessment in children.
Understanding age-related macular degeneration
Authors: Peto Tunde 
Published: July 2023

Understanding age-related macular degeneration
Tunde Peto, Professor of Clinical Ophthalmology at Queen’s University Belfast, describes the symptoms, causes and treatments for age-related macular degeneration and how the prevalence of the disease could be reduced. Imagine living your life without being able to see the face of your loved ones, being able to read your phone, book a show, rebook a cancelled flight, or read the labels in the supermarket. Such tasks we do without giving these much thought until suddenly, one day, we realise that we cannot do them. Age-related macular degeneration (AMD) can lead to the loss of central vision, causing sight loss or even legal blindness. This disease is the most common cause of blindness in those over 65, (1) and while it is genetically driven in most cases, not everyone will get the disease, even if they are at risk. Its effect can be devastating, especially for those with multiple comorbidities, who have no immediate social support and for whom reading, writing, or watching television or the birds might have been the major contributor to maintaining good mental health.(2)
Understanding immune mechanisms to create novel treatments for primary biliary cholangitis
Authors: Umeshappa Channakeshava S 
Published: July 2023

Understanding immune mechanisms to create novel treatments for primary biliary cholangitis
Professor Channakeshava S Umeshappa from Dalhousie University discusses the burden of primary biliary cholangitis and how understanding immune mechanisms may help to treat it. Primary biliary cholangitis (PBC) is characterised by chronic inflammation of the interlobular bile ducts, leading to fibrosis, cirrhosis, and liver failure if left untreated. Symptoms of PBC include fatigue, jaundice, itchy skin, abdominal pain, nausea or vomiting, dry eyes and mouth, and bone and joint aches. The incidence of PBC is increasing worldwide,(1) but is most common in Europe and North America.(2) PBC has a female predominance, affecting primarily middle-aged women (over 90% of the PBC cases). Clinically, it is often diagnosed by detecting anti-mitochondrial autoantibodies and elevated alkaline phosphatase enzymes in blood tests.
Understanding HIV risk in older adults
Authors: Conner Laneshia 
Published: July 2023

Understanding HIV risk in older adults
Laneshia Conner, Assistant Professor at the University of Kentucky, discusses gaps in HIV and AIDS prevention and why greater awareness and support for HIV risk in older adults is needed. When AIDS (acquired immunodeficiency syndrome) appeared in the 1980s, blood transfusions were the route of transmission and heavily impacted older adults (those aged 50 and above). Individuals deemed ‘at-risk’ were those who received transfusions before 1985. The social stigma surrounding HIV (human immunodeficiency virus) and AIDS as a disease primarily affecting White, homosexual males or individuals living in Sub-Saharan Africa has resulted in a lack of awareness among people outside of these groups, making it difficult for them to connect with and internalise the reality that anyone can be affected by the virus.
Progress in development of disease-modifying treatments in Parkinson's Disease
Authors: Huttunen Henri 
Published: July 2023

Progress in development of disease-modifying treatments in Parkinson's Disease
Henri Huttunen, Chief Scientific Officer, Herantis Pharma Plc, charts progress in the development of disease-modifying treatments for Parkinson’s disease. Recent FDA approvals of two potentially disease-modifying Alzheimer’s disease drugs give hope that similar successes in Parkinson’s disease may be around the corner. However, despite the recent advances in understanding complex disease biology and the development of novel drug targets and biomarkers, progress in the clinical development of new treatments remains slow.
New care models for older adults seeking emergency care
Authors: Robinson Katie , Galvin Rose 
Published: July 2023

New care models for older adults seeking emergency care
Professors Katie Robinson and Rose Galvin from the Ageing Research Centre at the University of Limerick describe research on new models of care for older adults seeking emergency care. Research notes that emergency department crowding leads to long waiting times, treatment delays, increased costs, staff burnout and reduced patient satisfaction. While the problem of emergency department crowding is multifaceted and complex, and no magic bullet will resolve the issue, researchers at the Ageing Research Centre UL are exploring how new modes of care for older adults seeking emergency care can improve their overall care experience and clinical outcomes while reducing unscheduled care use. Analysing two trials, the OPTIMEND randomised controlled trial and the ED PLUS pilot trial, the University of Limerick plans to establish what outcomes should be evaluated in ED studies with older adults. They will also be working to develop standards of care for frail older adults attending the ED and a larger-scale evaluation of ED PLUS as well.
Supporting Europe's transition to climate-neutral farming
Authors: Bergez Jacques-Eric 
Published: July 2023

Supporting Europe's transition to climate-neutral farming
We hear from ClieNFarms, an Innovation Action project funded by the European Commission to support the European Green Deal and achieve climate-neutral farming across Europe’s agricultural industry by 2050. Farmers play a critical role in ensuring food sustainability. They are responsible for producing the food we eat, but farming practices can significantly impact the environment and the long-term availability of resources. Although agriculture contributes 10.3% of the EU’s greenhouse gas emissions, it has strong potential for climate mitigation through soil carbon sequestration and storage, albedo effects, and the reduction of greenhouse gases etc. (1) More real-life experiments, clarification, and support are required for climate neutrality and climate-resilient farming. One recent example is the EU carbon removal certification framework proposal, which ‘aims to scale up carbon removal activities and fight greenwashing by empowering businesses to show their action in this field’.(2) As well as being an essential initial step, the proposal further solidified the importance of farming practices and the need for sustainable carbon farming solutions.