bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ultraschallgeräte für die abdominelle Diagnostik: neue Techniken und Applikationen – Was gibt es? Was ist möglich? Was ist sinnvoll?
Authors: Karlas Thomas , Blank Valentin , Trenker Corinna , Ignee André , Dietrich Christoph F. 
Published: January 2023

ZusammenfassungDie Ultraschalldiagnostik ist in vielen klinischen Situationen das Verfahren der ersten
Wahl für die abdominelle Bildgebung. Neben dem Graustufenbild (B-Modus) und den klassischen
Dopplerverfahren ermöglichen die kontrastmittelverstärkte Sonografie (CEUS), die Elastografie
und die Fettquantifizierung eine multimodale Charakterisierung von Organen und
Gewebestrukturen. Panorama- und 3D-Verfahren sowie Bildfusion haben die Befunddarstellung
erweitert. Die Entwicklung tragbarer Kleingeräte führt zu einer Erweiterung der
Einsatzmöglichkeiten der konventionellen Ultraschalldiagnostik.In dieser Übersichtsarbeit werden moderne sonografisch relevante Verfahren diskutiert
sowie Geräteklassen und Stufenkonzepte beschrieben und anhand der wissenschaftlichen Evidenz
bewertet. Ferner werden Hinweise zu Qualitätsstandards für die abdominelle
Ultraschalldiagnostik vermittelt.
First clinical experience with esophageal ESD using a novel adjustable traction device
Authors: Miyazaki Kurato , Kato Motohiko , Sasaki Motoki , Iwata Kentaro , Masunaga Teppei , Kubosawa Yoko , Hayashi Yukie , Mizutani Mari , Takatori Yusaku , Matsuura Noriko , Nakayama Atsushi , Takabayashi Kaoru , Nakajima Kiyokazu , Kanai Takanori , Yahagi Naohisa 
Published: January 2023

Abstract
Background and study aims In esophageal endoscopic submucosal dissection (ESD), the effectiveness of traction including clip-thread method has been reported, but it is difficult to adjust the direction of traction. Therefore, we developed a dedicated over-tube type traction device (ENDOTORNADO) that has a working channel and allows traction from any directions by rotating itself. We investigated the clinical feasibility and potential usefulness of this new device in esophageal ESD.
Patients and methods This was a single-center, retrospective study. Six cases of esophageal ESD with ENDOTORNADO from January to March 2022 (tESD group) were compared with 23 cases of conventional esophageal ESD performed by the same operator from January 2019 to December 2021 (cESD group) in terms of clinical treatment outcomes.
Results In all cases, en bloc resection was achieved without intraoperative perforation. The total procedure speed was significantly increased in tESD group (23 vs. 30 mm2/min, P = 0.046). In particular, the submucosal dissection time was significantly reduced to about one-quarter in tESD group (11 vs. 42 min, P = 0.004).
Conclusions ENDOTORNADO creates the adjustable traction from any directions and may have the clinical feasibility. It would be an option for human esophageal ESD.
Personalized endoscopic surveillance and intervention protocols for patients with familial adenomatous polyposis: the European FAP Consortium strategy
Authors: Aelvoet Arthur S. , Pellisé Maria , Bastiaansen Barbara A.J. , van Leerdam Monique E. , Jover Rodrigo , Balaguer Francesc , Kaminski Michal F. , Karstensen John G. , Saurin Jean-Christophe , Hompes Roel , Bossuyt Patrick M.M. , Ricciardiello Luigi , Latchford Andrew , Dekker Evelien ,   European FAP Consortium
Published: January 2023

Abstract
Background and study aims Patients with familial adenomatous polyposis (FAP) undergo colectomy and lifelong endoscopic surveillance to prevent colorectal, duodenal and gastric cancer. Endoscopy has advanced significantly in recent years, including both detection technology as well as treatment options. For the lower gastrointestinal tract, current guidelines do not provide clear recommendations for surveillance intervals. Furthermore, the Spigelman staging system for duodenal polyposis has its limitations. We present a newly developed personalized endoscopic surveillance strategy for the lower and upper gastrointestinal tract, aiming to improve the care for patients with FAP. We aim to inform centers caring for FAP patients and encourage the discussion on optimizing endoscopic surveillance and treatment in this high-risk population.
Methods The European FAP Consortium, consisting of endoscopists with expertise in FAP, collaboratively developed new surveillance protocols. The proposed strategy was consensus-based and a result of several consortium meetings, discussing current evidence and limitations of existing systems. This strategy provides clear indications for endoscopic polypectomy in the rectum, pouch, duodenum and stomach and defines new criteria for surveillance intervals. This strategy will be evaluated in a 5-year prospective study in nine FAP expert centers in Europe.
Results We present a newly developed personalized endoscopic surveillance and endoscopic treatment strategy for patients with FAP aiming to prevent cancer, optimize endoscopic resources and limit the number of surgical interventions. Following this new strategy, prospectively collected data in a large cohort of patients will inform us on the efficacy and safety of the proposed approaches.
NOBF4-Mediated Assembly of the Sydnone Imine Scaffold in the Synthesis of Double Nitric Oxide Donors
Authors: Fershtat Leonid L. , Shuvaev Alexander D. , Zhilin Egor S. 
Published: January 2023

AbstractA direct approach toward the construction of furoxan-sydnone imine double NO-donors involving the NOBF4-mediated nitrosation–cyclization sequence of α-amino nitriles as a key synthetic step was developed. The described protocol excludes the isolation of carcinogenic N-nitrosamines, operates broad substrate scope, and enables the preparation of fully substituted sydnone imines linked to the furoxan ring via different linkers or directly through C–C bond. Synthesized library of furoxan-sydnone imine hybrids demonstrated a promising ability to release NO in a wide range of concentrations which is useful for various biomedical insights.
SbCl3-Initiated Csp3
–Csp3
Coupling between N-Aryltetrahydroisoquinolines and Nitroalkanes via the Aerobic Oxidation of sp3
C–H Bond
Authors: Yuan Yu , Jia Xiaodong , Ma Qiyuan , Zhang Shuwei , Li Yuemei , Ding Han , Sun Zheng 
Published: January 2023

AbstractAn SbCl3-initiated Csp3
–Csp3
coupling between N-aryltetrahydroisoquinolines and nitromethanes was realized through the aerobic oxidation of sp
3 C–H bond, providing a series of nitromethylated tetrahydroisoquinoline derivatives in high yields. The results exhibited that SbCl3, as a cheap and commercially available reagent, is an efficient initiator to promote the direct functionalization of sp3
C–H bond with broad functional group tolerance, which is potentially applied to a wider range of C–H bond activation reactions.
Term Neonatal Outcomes after Maternal Magnesium Sulfate Treatment for Seizure Prophylaxis
Authors: Chornock Rebecca , Trieu Elissa , Kawakita Tetsuya , Dean Brynley , Overcash Rachael 
Published: January 2023

Objective This study aimed to evaluate term neonatal outcomes after maternal magnesium sulfate (MgSO4) treatment for seizure prophylaxis.
Study Design This was a single-site retrospective cohort study of all women with term singleton gestation requiring MgSO4 treatment for seizure prophylaxis and their respective neonatal outcomes from January 2013 through December 2020. Our primary outcome was neonatal intensive care unit (NICU) admission. We compared outcomes between women treated with MgSO4 for 24 hours or more and women treated with MgSO4 for less than 24 hours prior to delivery. Multivariable logistic regression was performed to calculate adjusted odds ratio (aOR) and 95% confidence interval (95% CI), controlling for variables with a p < 0.05 based on bivariable analysis.
Results Of 834 women analyzed, 173 (20.7%) neonates were admitted to the NICU. Women treated with MgSO4 for 24 hours or more compared with women treated with MgSO4 for less than 24 hours were more likely to have neonates admitted to the NICU during their hospitalization (27.3 vs. 18.9%; p = 0.01), neonates requiring immediate NICU admission (24.6 vs. 18.3%; p < 0.01), and NICU admission for neonatal lethargy. After adjusting for covariates, only NICU admission due to neonatal lethargy remained statistically significant (aOR: 4.78 [95% CI: 1.50–15.21]).
Conclusion Prolonged MgSO4 treatment for 24 hours or more was associated with increased odds of term NICU admission due to neonatal lethargy.
Key Points
Benzo-Fused 7-Oxabicyclo[2.2.1]heptane-2,3-diol Derivatives as Universal Linkers for Solid-Phase Oligonucleotide Synthesis
Authors: Hari Yoshiyuki , Fuchi Yasufumi , Yamamoto Kazuki , Ito Yuta 
Published: January 2023

AbstractIn solid-phase oligonucleotide (ON) synthesis, especially for 3′-modified ONs, a universal linker attached to a solid support is widely used. In this study, benzo-fused 7-oxabicyclo[2.2.1]heptane-2,3-diol derivatives are designed, synthesized, and evaluated as universal linkers. The designed linkers show reactivity comparable to that of a conventional universal linker for releasing the desired ONs. Additionally, these materials exhibit a more robust structure under basic conditions, as generally used in ON synthesis, and hydrophobic properties relative to the conventional universal linker. Notably, when diphenyl-substituted (terphenyl) and phenanthrene-type (PT) linkers are used, cyclic phosphodiesters derived from linker units as byproducts, which are produced by release of ONs from the linker units, are detected in the HPLC chromatograms. The PT linker is applicable to various ON syntheses using controlled pore glass (CPG) and polystyrene (PS) resins. These results demonstrate that the PT linker can serve as an alternative to conventional universal linkers.
Effect of stimulation frequency on hippocampal electric field induced by deep-brain magnetic stimulation
Authors: Xu Xiang-yang , Deng Bin , Wang Jiang , Yi Guo-sheng 
Published: January 2023

Deep-brain Magnetic Stimulation (DMS) is a noninvasive brain modulation method that improves hippocampal neural activity. The frequency of DMS has a significant effect on the hippocampal induced electric field. In this paper, we investigate the relationship between stimulation frequency and DMS-induced hippocampal electric field. The frequency sensitivity and distribution uniformity of the hippocampal electric field are calculated to quantify this relationship. The results show that the DMS-induced hippocampal electric field has a frequency-dependent property. The frequency sensitivity of the DMS-induced hippocampal electric field in the high frequency band is lower than that in the low frequency band, which corresponds to the low-pass filtering property of the neuron membrane. The frequency sensitivity of DMS-induced hippocampal electric field is highest in the range of 30–40 Hz. The uniformity of the hippocampal electric field induced by a single coil also reaches the highest in the range of 30–40 Hz, while uniformity of the hippocampal electric field induced by multiple-coil increases with increasing frequency. The frequency-dependent property of the DMS-induced hippocampal electric field is positively correlated with the quantity and size of coils, while negatively correlated with the spacing of the coils. This study is of great help in the selection of DMS frequencies and the design of coils.
Effects of helicopter net gunning on the survival and movement behaviour of nilgai antelope
Authors: Baumgardt Jeremy A. , Foley Aaron M. , Sliwa Kathryn M. , DeYoung Randy W. , Ortega-S. J. Alfonso , Hewitt David G. , Campbell Tyler A. , Goolsby John A. , Lohmeyer Kim H. 
Published: January 2023

Context Research on large, terrestrial mammals often requires physical captures to attach tags or collars, collect morphological data, and collect biological samples. Choice of capture method should minimise pain and distress to the animal, minimise risk to personnel, and consider whether the method can achieve study objectives without biasing results. Aims We studied how capture via helicopter net-gunning affected survival, post-capture movement patterns, and space use of exotic nilgai (Boselaphus tragocamelus) in southern Texas, USA. Methods We estimated daily survival rates for 101 collared nilgai over 28 days, following 125 captures. We calculated mean daily movement rates and net-squared displacement for 21 recaptured nilgai for 60 days, starting 30 days before capture. Key results The survival probability of 125 nilgai individuals was 0.97 (95% CI = 0.92–0.99) over the 28 days following capture, with the lowest daily survival for the day after capture ( x ¯ WR22049_IE1.gif = 0.99; 95% CI = 0.96–1.00). We observed an increase of ~65% in the mean daily movement rate of 134 m/h on the first 2 days since capture, followed by a period of reduced movement out to the 5th day before returning to pre-capture levels. Analysis of net-squared displacement for 21 nilgai showed that 17 resumed pre-capture space-use patterns within a week, whereas four individuals did not return to the pre-capture range for ≥1 month. Conclusions Capture-related mortality rates for nilgai using helicopter net-gunning in our study (3%) were similar or lower than those reported for similar species captured using the same method. While we were able to detect a period of elevated movement rates, followed by a recovery period of diminished movement as a result of capture, nilgai appeared to return to typical behaviour ~6 days post-capture. Most nilgai in our study also resumed typical space-use patterns within a week of capture; however, our results suggest high individual variability in their response. Implications We recommend using net-gunning from a helicopter as a method for capturing nilgai when conditions and where vegetation and topography allow. We suggest censoring data for a minimum of 7 days following capture for analyses related to survival and movement rates. For analyses relating to space use, we suggest inspecting net-squared displacement or some similar displacement analysis for each animal separately to account for individual variation in response and exclude data accordingly.
Ultrabroadband plasmon driving selective photoreforming of methanol under ambient conditions
Authors: Uddin Nasir , Sun Zhehao , Langley Julien , Lu Haijiao , Cao Pengfei , Wibowo Ary , Yin Xinmao , Tang Chi Sin , Nguyen Hieu T. , Evans Jack D. , Li Xinzhe , Zhang Xiaoliang , Heggen Marc , Dunin-Borkowski Rafal E. , Wee Andrew T. S. , Zhao Haitao , Cox Nicholas , Yin Zongyou 
Published: January 2023

Liquid methanol has the potential to be the hydrogen energy carrier and storage medium for the future green economy. However, there are still many challenges before zero-emission, affordable molecular H
2
can be extracted from methanol with high performance. Here, we present noble-metal-free Cu–WC/W plasmonic nanohybrids which exhibit unsurpassed solar H
2
extraction efficiency from pure methanol of 2,176.7 µmol g
−1
h
−1
at room temperature and normal pressure. Macro-to-micro experiments and simulations unveil that local reaction microenvironments are generated by the coperturbation of WC/W’s lattice strain and infrared-plasmonic electric field. It enables spontaneous but selective zero-emission reaction pathways. Such microenvironments are found to be highly cooperative with solar-broadband-plasmon-excited charge carriers flowing from Cu to WC surfaces for efficient stable CH
3
OH plasmonic reforming with C
3
-dominated liquid products and 100% selective gaseous H
2
. Such high efficiency, without any CO
x
emission, can be sustained for over a thousand-hour operation without obvious degradation.
Production of brain-derived neurotrophic factor gates plasticity in developing visual cortex
Authors: Kaneko Megumi , Stryker Michael P. 
Published: January 2023

We have previously shown that recovery of visual responses to a deprived eye during the critical period in mouse primary visual cortex requires phosphorylation of the TrkB receptor for BDNF [M. Kaneko, J. L. Hanover, P. M. England, M. P. Stryker,
Nat. Neurosci.

11
, 497–504 (2008)]. We have now studied the temporal relationship between the production of mature BDNF and the recovery of visual responses under several different conditions. Visual cortical responses to an eye whose vision has been occluded for several days during the critical period and is then re-opened recover rapidly during binocular vision or much more slowly following reverse occlusion, when the previously intact fellow eye is occluded in a model of “patch therapy” for amblyopia. The time to recovery of visual responses differed by more than 18 h between these two procedures, but in each, the production of mature BDNF preceded the physiological recovery. These findings suggest that a spurt of BDNF production is permissive for the growth of connections serving the deprived eye to restore visual responses. Attenuation of recovery of deprived-eye responses by interference with TrkB receptor activation or reduction of BDNF production by interference with homeostatic synaptic scaling had effects consistent with this suggestion.
An omnidirectional seismic image extension
Authors: Kroode Fons ten 
Published: January 2023

Abstract
This paper introduces an operator, which extends the Born operator for the linearized variable density acoustic wave equation. Inspired by angle dependent scattering, I will define it as acting on distributions depending on space and angle coordinates. I will show that it can be written as a weighted integral of space-shift extended operators associated to arbitrary directions after a suitable coordinate transform. I will also formulate conditions under which its normal operator is a pseudo-differential operator. These will be seen to be less restrictive than the ones imposed on horizontal space-shift extended operators in the sense that they allow diving wave paths.
Torr-level, seedless, non-resonant velocity distribution function measurement with a dual-color, single-shot coherent Rayleigh–Brillouin scattering scheme
Authors: Bak Junhwi , Randolph Robert , Gerakis Alexandros 
Published: January 2023

Abstract
A two order of magnitude spectral acquisition improvement in velocity distribution function measurement is demonstrated with a novel single-shot, dual-color coherent Rayleigh–Brillouin scattering (CRBS) scheme. By performing this non-resonant and seedless spectral diagnostic technique, capable of obtaining a spectrum in

∼

300

ns, we demonstrate accurate temperature (ranging from 300 K to 500 K) and pressure (ranging from 760 Torr down to 1 Torr) measurement capabilities, for a variety of atomic, molecular and multispecies gases. This demonstrated gas thermodynamic characterization capability of the dual-color CRBS scheme over broad ranges of pressure and temperature for a variety of gases is anticipated to be of great interest to a plethora of fields, ranging from aerospace applications to low-temperature plasmas, providing with an accurate measurement of physical properties of neutral particles, for a range of gases.
Precise perturbative predictions from fixed-order calculations
Authors: Yan Jiang , Wu Zhi-Fei , Shen Jian-Ming , Wu Xing-Gang 
Published: January 2023

AbstractThe intrinsic conformality (iCF) is a general property of the renormalizable gauge theory, which ensures the scale invariance of a fixed-order series at each perturbative order. Following the idea of iCF, we suggest a novel single-scale setting approach under the principle of maximum conformality (PMC) with the purpose of removing the conventional renormalization scheme and scale ambiguities. We call this newly suggested single-scale procedure the PMC∞-s approach, in which an overall effectiveαs, and hence an overall effective scale is achieved by identifying the {β0} terms at each order. Its resultant conformal series is scale-invariant and satisfies all renormalization group requirements. The PMC∞-s approach is applicable to any perturbatively calculable observable, and its resultant perturbative series provides an accurate basis for estimating the contribution from the unknown higher-order (UHO) terms. Using the Higgs decay into two gluons up to five-loop quantum chromondynamics (QCD) corrections as an example, we show how the PMC∞-s works, and we obtainΓHPMC∞−sPAA=334.45−7.03+7.07KeVandΓHPMC∞−sB.A.=334.45−6.29+6.34KeV. Here the errors are squared averages of those mentioned in the body of the text. ThePadéapproximation approach (PAA) and the Bayesian approach (BA) have been adopted to estimate the contributions from the UHO terms. We also demonstrate that the PMC∞-s approach is equivalent to our previously suggested single-scale setting approach (PMCs), which also follows from the PMC but treats the {βi} terms from a different point of view. Thus, proper use of the renormalization group equation can provide a solid way to solve the scale-setting problem.
Carrier and phonon transport in 2D InSe and its Janus structures
Authors: Wan Wenhui , Guo Rui , Ge Yanfeng , Liu Yong 
Published: January 2023

Abstract
Recently, two-dimensional (2D) Indium Selenide (InSe) has been receiving much attention in the scientific community due to its reduced size, extraordinary physical properties, and potential applications in various fields. In this review, we discussed the recent research advancement in the carrier and phonon transport properties of 2D InSe and its related Janus structures. We first introduced the progress in the synthesis of 2D InSe. We summarized the recent experimental and theoretical works on the carrier mobility, thermal conductivity, and thermoelectric characteristics of 2D InSe. Based on the Boltzmann transport equation (BTE), the mechanisms underlying carrier or phonon scattering of 2D InSe were discussed in detail. Moreover, the structural and transport properties of Janus structures based on InSe were also presented, with an emphasis on the theoretical simulations. At last, we discussed the prospects for continued research of 2D InSe.
Simultaneous multi-segment (SMSeg) EPI over multiple focal regions
Authors: Sun Kaibao , Zhong Zheng , Dan Guangyu , Wang Kezhou , Karaman M Muge , Luo Qingfei , Zhou Xiaohong Joe 
Published: January 2023

Abstract

Objective. This study aimed at developing a simultaneous multi-segment (SMSeg) imaging technique using a two-dimensional (2D) RF pulse in conjunction with echo planar imaging (EPI) to image multiple focal regions. Approach. The SMSeg technique leveraged periodic replicates of the excitation profile of a 2D RF pulse to simultaneously excite multiple focal regions at different locations. These locations were controlled by rotating and scaling transmit k-space trajectories. The resulting multiple isolated focal regions were projected into a composite ‘slice’ for display. GRAPPA-based parallel imaging was incorporated into SMSeg by taking advantage of coil sensitivity variations in both the phase-encoded and slice-selection directions. The SMSeg technique was implemented at 3 T in a single-shot gradient-echo EPI sequence and demonstrated in a phantom and human brains for both anatomic imaging and functional imaging. Main results. In both the phantom and the human brain, SMSeg images from three focal regions were simultaneously acquired. SMSeg imaging enabled up to a six-fold acceleration in parallel imaging without causing appreciable residual aliasing artifacts when compared with a conventional gradient-echo EPI sequence with the same acceleration factor. In the functional imaging experiment, BOLD activations associated with a visuomotor task were simultaneously detected in two non-coplanar segments (each with a size of 240 × 30 mm2), corresponding to visual and motor cortices, respectively. Significance. Our study has demonstrated that SMSeg imaging can be a viable method for studying multiple focal regions simultaneously.