bluuebunny/crossref_metadata_2025_split huggingface dataset:
Performances Investigation of the Eco-friendly Refrigerant R13I1 used as Working Fluid in the Ejector-Expansion Refrigeration Cycle
Authors: MAALEM Youcef , TAMENE Youcef , MADANI Hakim 
Published: August 2023

Knowing that from 2030 refrigerants used in refrigerating engineering should have a global warming potential (GWP) of less than 150. Searching for eco-friendly refrigerants with good performance and minimal environmental impact to substitute conventional working fluids such as R134a (GWP=1430) represents a great challenge for researchers.
The present research aims to investigate and compare the performances of the eco-friendly refrigerant R13I1 (Zero GWP) used as a possible new working fluid in the ejector-expansion refrigeration cycle (EERC) with the commonly used R134a which has good performances but a high GWP. To reach this objective, a numerical program was developed using MATLAB software to evaluate the coefficient of performance (COP), the entrainment ratio (µ), the exergy destruction and the exergy efficiency for both refrigerants. Furthermore, the effect of the diffuser efficiency of the ejector on the COP and the compressor work was explored. Furthermore, the effect of the diffuser efficiency of the ejector on the COP, and the compressor work were explored. The simulation was realized for Tc selected between 30 and 55 °C and Te ranging between -10 and 10 °C. Results proved that the use of R13I1 as a working fluid in the EERC system exhibited a higher COP, µ, and exergy efficiency, as well as lower exergy destruction compared with R134a under the same operating temperatures. On another hand, the energetic analysis revealed that as Tc increases the COP and µ decrease. However, as Te varies from -10 and 10 °C, the COP and µ increase. Regarding exergy analysis, it should be noted that both exergy destruction and exergy efficiency are sensitively influenced by Tc more than Te. Overall, the study confirms that R13I1 could be a suitable substitute for the phase-out R134a in terms of performance and environmental protection.
Kebutuhan tenaga kerja, WISN ANALISIS KEBUTUHAN TENAGA KERJA REKAM MEDIS UNIT RAWAT JALAN DENGAN METODE WORKLOAD INDICATOR STAFFING NEED (WISN) DI RUMAH SAKIT SITI MIRIAM LAWANG
Authors: HARI SUKMA SEPTYA ANGGARI SALSA 
Published: August 2023

Metode WISN (Workload Indicator Staffing Needs), berfungsi sebagai perhitungan dalam kebutuhan sumber daya manusia (SDM) dengan menggunakan beban kerja oleh SDM kesehatan pada seluruh unit kerja pada fasilitas pelayanan. Petugas pendaftaran bertugas melayani pasien, selain itu petugas kasir juga ikut membantu melayani pendaftaran. Kegiatan yang dilakukan tidak hanya melayani pendaftaran saja, tetapi juga merangkap filing dan kasir. Tujuan penelitian ini untuk menganalisis kebutuhan tenaga rekam medis pada bagian pendaftaran URJ di Rumah Sakit Siti Miriam Lawang dengan pasien berjumlah 5.863 tahun 2021. Jenis penelitian deskriptif dengan pendekatan kuantitatif, sampel dan populasi petugas pendaftaran URJ, menggunakan pendekatan croos sectional. menggunakan pengumpulan data, wawancara dan observasi. Berdasarkan hasil wawancara, observasi dan perhitungan WISN didapatkan hasil bahwa seharusnya terdapat penambahan petugas agar pelayanan lebih maksimal dan sesuai dengan tupoksi.
Peningkatan Derajat Kesehatan Lansia Jamaah Masjid Al Furqon Melalui Screening Tekanan Darah, Gula Darah, Asam Urat dan Kolesterol
Authors: Handayani Fitri , Winarsih Wiwin , Abidah Alief Nur Insyiroh 
Published: August 2023

Penyakit Tidak Menular (PTM) merupakan faktor penyebab kematian secara global dan salah satu faktor tantangan yang besar di abad 21. PTM terus meningkat persentasenya dengan dampak utama kematian dan penurunan kualitas hidup. Empat kunci metabolik dalam peningkatan PTM adalah tekanan darah, indeks massa tubuh, glukosa darah dan kadar kolesterol darah. Kegiatan ini merupakan salah satu upaya promotif dan preventif dalam mendeteksi dini adanya permasalahan kesehatan lansia terutama adanya masalah penyakit tidak menular. Pengabdian masyarakat ini berupa screening kesehatan melalui pemeriksaan kesehatan berupa tekanan darah, gula darah, asam urat dan kolesterol. Kegiatan ini dilaksanakan pada tanggal 30 Juli 2022 pukul 07.00-10.00 WIB di Masjid Al-Furqon Jl. Nitikan Baru Yogyakarta. Hasil pemeriksaan menunjukkan bahwa dari 92 peserta yang diperiksa, didapatkan hasil bahwa 38 peserta dalam keadaan sehat karena memiliki hasil pemeriksaan tekanan darah, gula darah, asam urat, dan kolesterol dalam batas normal. 44 peserta mengalami hipertensi, 27 mengalami kadar gula darah diatas normal, 21 peserta memiliki kadar asam urat diatas batas normal, dan 16 peserta memiliki kadar kolesterol diatas batas nomal.
Global Experience of Digitalization of Economic Processes in the Context of Transformation
Authors: Bielialov Taliat , Kalina Iryna , Goi Vasyl , Kravchenko Oleksii , Shyshpanova Nataliia , Negoda Anna 
Published: August 2023

Purpose: The article aims to clarify the peculiarities of the main trends, advantages, and disadvantages of digitalization of the economy in the context of reorganization processes in different countries of the world.

Theoretical framework: Today, significant competitive advantages can be achieved through the effective management of available company resources based on innovative technologies and methods of business process optimization. Due to the continuous improvement of the digital environment, they are becoming an important management tool and a key development factor.

Design/methodology/approach: When studying the issues related to the topic of this research, the analytical and bibliographic method was applied to study the scientific literature on the digitalization of economic processes. Abstraction, idealization, induction, deduction, analysis, synthesis of information, and system-structural, comparative, logical, and linguistic methods were utilized to study and process data. Moreover, the authors conducted an online questionnaire survey to clarify the most important issues related to the use of electronic means in the world economy.

Findings: The study identified the most important theoretical aspects of the issues related to the use of digital technologies in the economies of different countries of the world. Furthermore, the views of scientists and managers of companies that use electronic forms of business organization in their work on key aspects of this issue are studied.

Research, Practical & Social implications: The analysis of the scientific literature on the research topic and the results of the questionnaire survey showed that digitalization in the field of economy is the process of transferring economic activity to a new format. It involves the use of digital technologies and helps to optimize business processes, increase business income and improve the system of communication with consumers

Originality/value: The authors conducted an online questionnaire survey to clarify the most important issues related to the use of electronic means in the world economy.
Public-Private Partnerships in Natural Resource Management as a Basis for the Implementation of the Ecological and Economic Security Doctrine of Ukraine's Development
Authors: Tarasenko Iryna , Kruhlov Vitalii , Stepanenko Tetiana , Moroz Galyna , Lebedchenko Vira 
Published: August 2023

Purpose: This article aims to identify the main tendencies and features of public-private partnerships in the environmental sphere regarding developing environmental and economic security in Ukraine.

Theoretical framework: Business cost savings when implementing the latest technologies in pursuit of economic results are accompanied by a deterioration of the environmental situation at the regional and national levels, increased risks of negative impact on population health, and reduced labor productivity, which, accordingly, causes a potential increase in public healthcare costs. As a result, the search for forms and methods to ensure effective cooperation between the state and business in solving natural resources management problems is intensifying.

Design/methodology/approach: The study used analytical and bibliographic methods to study the scientific literature on implementing the ecological and economic security doctrine and the features of various types of public-private partnerships related to it, as well as induction, deduction, analysis, synthesis of information, systemic and structural, comparative, logical, and linguistic methods, abstraction, idealization for studying and processing data, and a questionnaire survey conducted by the research authors online to clarify the most critical issues related to this issue practically.

Findings: The study identified the principal and most important theoretical aspects of public-private partnership issues in the environmental sector.

Research, Practical & Social implications: Also, it examined the opinion of representatives of public environmental organizations and executives of local government departments on the critical aspects of the problem.

Originality/value: One of the most effective forms of combining the efforts of all stakeholders is a public-private partnership, which in a market economy allows directing limited resources of business and the state to solve the most pressing problems of both certain regions and the country as a whole through the mechanism of joint implementation of socially significant projects.
Improving the Efficiency of Management of Large International Companies for the Development of Financial and Economic Cooperation Between Countries, Given Migration
Authors: Berdiyorov Temur , Orozalieva Akima , Nazarkulova Gulzana , Fedoryshyna Kateryna , Galenko Oksana , Peredalo Khrystyna 
Published: August 2023

Purpose: The aim of this study is to analyze the relationship between the development of large international companies and migration. An equally important task is to improve the direction of financial and economic cooperation between exporting countries and countries receiving migrants.

Theoretical framework: The process of globalization caused by the accelerated development of production and technology is chaotic. At the same time, migration processes can create economic conditions aimed at improving socioeconomic, cultural, and political development in countries.

Methodology: The study uses general scientific and special research methods, namely the method of dialectical cognition, the method of induction and deduction, the method of scientific abstraction, the method of system analysis, the index system and evaluation method, the causal method, and the comparative method.

Findings: The article proves that the financial and economic interests of countries should be taken into account when cooperating with migration and other international policies. This direction of development is ensured by increasing the efficiency of the management of large international companies and improving the mechanisms of financing international migration processes. At present, the efficiency of management of large international companies is enhanced by creating a trilateral mutually beneficial situation when the immigration process has a positive impact on the country of origin, the country of destination, and the migrant.

Practical & Social implications: The positive impact of immigration is that immigrants use their rights in the host country to find work, develop skills and earn money, some of which they can transfer to their country of origin. The advantage of the destination country is that it can attract workers from unpopular countries who find jobs there.

Originality: The article proves that the positive effect is ensured by an increase in remittances and is seen as a new source of additional financing for economic development. Through remittances, migrants make a direct contribution to reducing poverty in their country of origin. In addition, the positive impact is also reflected in social communication, which is manifested in the flow of information, ideas, values.
Estimation of Greenhouse Gas Emission Burden of Livestock Sector in East Java Province, Indonesia
Authors: EDI DIDIK NUR , HARYUNI NINING 
Published: August 2023

Tujuan dari analisis ini adalah untuk memetakan kontribusi gas metana dan dinitro oksida dari sektor peternakan di setiap wilayah yang ada di Provinsi Jawa Timur sebagai dasar perencanaan dalam pengembangan kawasan peternakan yang berkelanjutan dan berwawasan lingkungan. Metode analisis menggunakan pendekatan analisis Tier 1. Data yang digunakan adalah data sekunder dari BPS Jawa Timur Tahun 2021. Hasil analisis menunjukkan bahwa beban gas rumah kaca di Provinsi Jawa Timur yaitu CH4 sebanyak 221,80 Gg CH4 Th-1 dan N2O sebanyak 168,42 Gg N2O Th-1 dengan profil beban tiap wilayah kabupaten/kota tidak merata. Beban gas rumah kaca tertinggi didapatkan di Kabupaten Malang. Penyumbang gas rumah kaca tertinggi dari sub sektor peternakan adalah ternak sapi potong sebesar 75,20% CH4 dan 52,30% N2O terhadap total sektor peternakan.
ABSTRACT
The purpose of this analysis is to map the contribution of methane gas and nitrous oxide from the livestock sector in each region in East Java Province as a basis for planning in the development of sustainable and environmentally friendly livestock areas. The analysis method uses a Tier 1 analysis approach. The data used is secondary data from the BPS East Java in 2021. The results of the analysis show that the greenhouse gas load in East Java Province is CH4 as much as 221.80 Gg CH4 per year and N2O as much as 168.42 Gg N2O per year where the load profile is uneven for each district/city. The highest greenhouse gas load was found in Malang Regency. The highest greenhouse gas contributor from the livestock sub-sector is beef cattle with 75.20% CH4 and 52.30% N2O of the total livestock sector.
A STUDY OF MMP7 EXPRESSION IN TRIPLE NEGATIVE BREAST CANCER PATIENTS
Authors: Vaniya Bhoomi , Patel Nupur , Vora Hemangini 
Published: August 2023

MMP7 has a part in preventing apoptosis and promoting angiogenesis. According to both in vivo and in vitro evidence, MMP7 is mostly seen during tumour invasion and metastasis. Controlling MMP7 expression may be a method for treating this cancer because its overexpression encourages the occurrence, progression, and invasiveness of breast cancer. The aim is to study the expression of MMP7 in triple negative breast cancer patients. Formalin fixed paraffin embedded breast tumor tissues from 50 triple negative breast cancer patients were collected for this study. immunohistochemistry method was used to study MMP7 expression and correlated with clinical and pathological parameters as well as disease status. MMP7 positivity was observed in 48% triple negative breast cancer patients. No significant correlation of MMP7 expression with age, menopausal status, tumour size, histopathology, stage and lymph node status were observed. A significant higher incidence of MMP7 expression was noted in patients with high grade tumor (63%) as compared to patients with low grade tumor (00%). Further, a significant higher incidence of MMP7 was observed in patients with high BR score (65%) as compared to the patients with low BR score (00%). Also, a significant higher incidence was observed in patients with relapse (63%) than patients in remission (35%). A significant higher incidence of MMP7 expression was observed with respect to disease free survival in univariate survival analysis. In multivariate survival analysis, for disease free survival MMP7 entered at step 1 and lymph node status and MMP7 entered at step 2. The findings imply that MMP7 is important for tumour invasion and metastasis, and that elevated MMP7 expression is associated with tumour development and recurrence.
ҮШІНШІ ЖЫНЫС ЖӘНЕ АИТВ-ИНФЕКЦИЯСЫ
Authors: Садыкова М.М. 
Published: August 2023

Эпидемия ВИЧ-инфекции в мире и Республике Казахстан обусловлена ростом заболеваемости в популяциях ключевых групп населения (КГН). Представители КГН относятся к девиациям в рамках бинарной гендерной системы. В ряде государств третий пол признан официально. Например, Великобритании, Австралии, Австрии, Новой Зеландии и многих других. В настоящий момент нормы гендера все больше размываются. И тем не менее представители этих популяций повсеместно подвергаются стигматизации. Медицинскому персоналу в Казахстане необходимо знать самим и осведомить пациентов о проводимых мероприятиях, таких, как открытие дружественных кабинетов, предоставления доконтактной (ДКП), постконтактной (ПКП) профилактики и другие меры и исключить стигматизацию, поскольку у нас высокие цели победить ВИЧ-инфекцию.
The epidemic of HIV infection in the world and the Republic of Kazakhstan is caused by an increase in morbidity in the populations of key population groups (KРG). Representatives of the KPG relate to deviations within the binary gender system. In a number of states, the third sex is officially recognized. For example, Great Britain, Australia, Austria, New Zealand and many others. At the moment, gender norms are increasingly being eroded. Nevertheless, representatives of these populations are stigmatized everywhere. Medical personnel in Kazakhstan need to know themselves and inform patients about the activities carried out, such as opening friendly offices, providing pre-contact (PPCP), post-contact (PCP) prevention and other measures and eliminate stigmatization, since we have high goals to defeat HIV infection.
The Microbiological Profile of Community-Acquired Pneumonia in Pediatric Patients in Brazil
Authors: Lima Guilherme Vieira , Leite Rafael Rodrigues , Oliveira Sandriny Maria de Almeida , Gomes Sara Maria Bié , Ferreira Sávio Benvindo 
Published: August 2023

Aims: Identifying the main pathogens causing Community Acquired Pneumonia in the pediatric population.
Study Design: It is a narrative review, a qualitative study.
Place and Duration of Study: Multidisciplinary Laboratory of Scientific Design and Writing (LaMDEC), Julio Bandeira University Hospital (HUJB), Cajazeiras, Paraíba, Brazil, from May 2023 to June 2023.
Methodology: A narrative literature review method was adopted, with research carried out in the following databases: Google Scholar, Scientific Scientific Electronic Library Online (SciELO), PubMed, LILACS and Virtual Health Library (BVS).
Results: A relevant prevalence of the bacterial pathogens Streptococcus pneumoniae, Mycoplasma pneumoniae and Staphylococcus aureus, and the viral etiological agent Respiratory Syncytial Virus, depending on the age of the affected patients, was observed in the literature in the pediatric population.
Conclusion: A relevant prevalence of the bacterial pathogens Streptococcus pneumoniae, Mycoplasma pneumoniae and Staphylococcus aureus, and the viral etiological agent Respiratory Syncytial Virus, depending on the age of the affected patients, was observed in the literature in the pediatric population. However, the means used to confirm the etiology are still lacking in their methodological reliability, a fact that makes it important for the scientific community to develop and adopt more effective methods for the microbiological determination of the causes of pneumonia.
Forecasting of Resin Yield and Number of Blazes of Naturally Regenerated Chir Pine (Pinus roxburghii Sargent) in Himachal Pradesh by Using Single Exponential Smoothing Method
Authors: Kumar Pawan , Gupta R. K. , Chandel Ashu , Dutt Bhupender , Sharma Subhash , Kaur Sukhdeep 
Published: August 2023

The present investigation entitled “Forecasting of resin yield and number of blazes of naturally regenerated chir pine (Pinus roxburghii Sargent) in Himachal Pradesh by using single exponential smoothing method” was carried out during the year 2020-2022. The secondary information was collected regarding the resin yield and number of resin blazes w.e.f. 2005 to 2022 from Himachal Pradesh State Forest Department. Exponential smoothing is a particular moving average technique applied to time series data and to produce smoothed data to make forecast. In exponential smoothing, one or more smoothing parameters are to be determined explicitly and those choices determine the weights assigned to the observations. Forecasting with the help of various linear and non-linear models is on the assumption that the series is stationary. Often time series is found to be non-stationary which means they are integrated and can be made stationary by differencing the time series. To check the stationarity of the number of blazes and resin yield, Augmented Dickey Fuller test was used. The results indicated that data was not approaching stationarity even after taking third difference. So, the prerequisite condition of ARIMA model is that the data should be stationary and if the time series data does not contain trend and seasonal components, Single Exponential Smoothing model was used. The Single Exponential Smoothing model was found to be best fit for the prediction of number of blazes and resin yield as per the high value of , low value of MAPE and Normalized BIC.
Germline Variants Incidentally Detected via Tumor-Only Genomic Profiling of Patients With Mesothelioma
Authors: Mitchell Owen D. , Gilliam Katie , del Gaudio Daniela , McNeely Kelsey E. , Smith Shaili , Acevedo Maria , Gaduraju Meghana , Hodge Rachel , Ramsland Aubrianna S. S. , Segal Jeremy , Das Soma , Hathaway Feighanne , Bryan Darren S. , Tawde Sanjukta , Galasinski Shelly , Wang Peng , Tjota Melissa Y. , Husain Aliya N. , Armato Samuel G. , Donington Jessica , Ferguson Mark K. , Turaga Kiran , Churpek Jane E. , Kindler Hedy L. , Drazer Michael W. 
Published: August 2023

ImportancePatients with mesothelioma often have next-generation sequencing (NGS) of their tumor performed; tumor-only NGS may incidentally identify germline pathogenic or likely pathogenic (P/LP) variants despite not being designed for this purpose. It is unknown how frequently patients with mesothelioma have germline P/LP variants incidentally detected via tumor-only NGS.ObjectiveTo determine the prevalence of incidental germline P/LP variants detected via tumor-only NGS of mesothelioma.Design, Setting, and ParticipantsA series of 161 unrelated patients with mesothelioma from a high-volume mesothelioma program had tumor-only and germline NGS performed during April 2016 to October 2021. Follow-up ranged from 18 months to 7 years. Tumor and germline assays were compared to determine which P/LP variants identified via tumor-only NGS were of germline origin. Data were analyzed from January to March 2023.Main Outcomes and MeasuresThe proportion of patients with mesothelioma who had P/LP germline variants incidentally detected via tumor-only NGS.ResultsOf 161 patients with mesothelioma, 105 were male (65%), the mean (SD) age was 64.7 (11.2) years, and 156 patients (97%) self-identified as non-Hispanic White. Most (126 patients [78%]) had at least 1 potentially incidental P/LP germline variant. The positive predictive value of a potentially incidental germline P/LP variant on tumor-only NGS was 20%. Overall, 26 patients (16%) carried a P/LP germline variant. Germline P/LP variants were identified in ATM, ATR, BAP1, CHEK2, DDX41, FANCM, HAX1, MRE11A, MSH6, MUTYH, NF1, SAMD9L, and TMEM127.Conclusions and RelevanceIn this case series of 161 patients with mesothelioma, 16% had confirmed germline P/LP variants. Given the implications of a hereditary cancer syndrome diagnosis for preventive care and familial counseling, clinical approaches for addressing incidental P/LP germline variants in tumor-only NGS are needed. Tumor-only sequencing should not replace dedicated germline testing. Universal germline testing is likely needed for patients with mesothelioma.