bluuebunny/crossref_metadata_2025_split huggingface dataset:
(338) YOUNG PEOPLE'S PROPOSALS FOR A WEB-BASED INTERVENTION FOR SEXUAL HEALTH PROMOTION: A FRENCH QUALITATIVE STUDY
Authors: Philippe Martin , Prof. Corinne Alberti , Serge Gottot , Aurélie Bourmaud , Elise de La Rochebrochard 
Published: July 2023

Abstract

Objectives
Promoting sexual health is key to improving the supportive behaviors and well-being of young people. With the advent of the Internet, web-based features for sexual health promotion may be attractive to a diverse range of young people. This study aims to assess young people's proposals regarding a web-based intervention for sexual health promotion.

Methods
Nineteen French young people aged 15-24 years participated to the study. In a semi-structured interview, they presented their views on a web-based intervention for sexual promotion. Data were coded with N’Vivo and subjected to qualitative thematic analysis to explore their proposals.

Results
The majority of participants (n=18) thought that a web-based intervention for sexual health promotion would be attractive. Young people interviewed made 31 concrete proposals for sexual health promotion on the Internet. Participatory and interactive dimensions on the internet appeared essential, with the need for stimulating activities and interaction with peers, but also with competent professionals and moderation. Face to the risks of the internet, they expressed the need of a secure and confidential space, to generate trust and participation in intervention. For participants, sexual health should be addressed in all its dimensions, taking into account the relational, sexual, and gender dimensions, and by incrementing on the internet valid, credible and personalized content.

Conclusions
In sexual health promotion, young people are indispensable stakeholders who can make concrete proposals and can also participate in content creation and research. More broadly, in health promotion, involving target audiences in decisions represents a promising perspective.

Conflicts of Interest
No conflict of interest.
(259) SEXUAL DIFFICULTIES AMONG MEN WITH VIOLENT SEXUAL INTERESTS
Authors: Dr. Ellen Zakreski , Dr. Jim Pfaus , Dr. Klara Bartova , Dr. Lucie Krejcova , Dr. Renata Androvicova , Dr. Katerina Klapilova 
Published: July 2023

Abstract

Objectives
Individuals with paraphilic interests such as sexual interests in rape, masochism or violent restraint, may have difficulties establishing healthy, consensual intimate relationships. We aimed to examine whether adults with violent sexual interest have difficulties synchronizing with their partner or achieving orgasm during sexual intercourse.

Methods
A nationally representative sample of 1193 Czech adults completed an online survey examining paraphilic interest and sexual functioning. Participants were asked about their experience of sexual synchrony (harmonizing rhythm during intercourse, eye contact, noticing partner’s vocalization, etc.). For a variety of sexual positions, participants were asked how frequently they engaged in that position, how appealing they found that position, and the percentage of time they experienced orgasm in that position. Participants also reported the percentage of time they acheived orgasm via masturbation. Structural equation modeling with confirmatory factor analysis was then used to test associations between violent paraphilic interest, the probability of orgasm, frequency, and appeal across sexual positions, as well as sexual synchrony while controlling for age.

Results
In both men and women, greater sexual synchrony was associated with a greater probability of orgasm across a range of sexual positions, controlling for the appeal of a particular position and its frequency. In women, violent paraphilic interest was not significantly associated with orgasm probability or sexual synchrony. However, men with greater violent paraphilic interest experienced fewer orgasms across a range of positions, and this effect was mediated by reduced sexual synchrony. Violent paraphilic interest was not associated with the probability of orgasm via masturbation.

Conclusions
These results suggest that men with greater violent sexual interest may have difficulty experiencing pleasure in dyadic sexual activities. Difficulties experiencing orgasm or synchronizing with their partner during intercourse could lead individuals to develop more extreme sexual fantasies. Psychotherapy for individuals with violent paraphilic interests should take into consideration potential sexual problems.

Conflicts of Interest
None to declare.
Seroconversion following empiric praziquantel treatment as confirmatory diagnostic tool for chronic schistosomiasis
Authors: Marangoni Davide , Manciulli Tommaso , Barbiero Anna , Mantella Antonia , Spinicci Michele , Bartoloni Alessandro , Zammarchi Lorenzo 
Published: July 2023

Highlight
We report on six patients with suspected chronic schistosomiasis and negative microbiological findings at baseline. All patients were treated empirically with praziquantel and all seroconverted 20 days to two months after treatment. We suggest that seroconversion after praziquantel treatment may be used as a confirmatory diagnostic tool for chronic schistosomiasis.
A novel high-resolution melting analysis strategy for detecting cystic fibrosis–causing variants
Authors: Díez Rodríguez Gerardo Raúl , Figueredo Lago Juan Emilio , Armas Cayarga Anny , González González Yaimé Josefina , García de la Rosa Iria , Collazo Mesa Teresa , López Reyes Ixchel , Batista Lozada Yulaimy , Rodríguez Calá Fidel Ramón , García Sánchez Juan Bautista 
Published: July 2023

Abstract
Cystic fibrosis (CF), an autosomal recessive disease, is caused by variants in both alleles of the CF transmembrane conductance regulator (CFTR) gene. A new assay based on allele-specific polymerase chain reaction and high-resolution melting analysis was developed for the detection of 18 CF-causing CFTR variants previously identified in Cuba and Latin America. The assay is also useful for zygosity determination of mutated alleles and includes internal controls. The reaction mixtures were normalized and evaluated using blood samples collected on filter paper. The evaluation of analytical parameters demonstrated the specificity and sensitivity of the method to detect the included CFTR variants. Internal and external validations yielded a 100% agreement between the new assay and the used reference tests. This assay can complement CF newborn screening not only in Cuba but also in Latin America.
Healthcare Services for Asylum-Seekers: Untangling the European Social Charter
Authors: Litins’ka Yana 
Published: July 2023

Abstract
Asylum-seekers, like any population, need healthcare services, yet national laws sometimes restrict access to such services. The European Social Charter (revised) protects the right to health and medical services. However, the Charter has a complex application, and its scope is limited concerning foreigners. This article analyses to what extent the provisions of the Charter on the right to health and medical assistance apply to adult asylum-seekers. It shows that the Charter may apply to various degrees to asylum-seekers depending on several circumstances, such as the national definition of residence or regular work, grounds for seeking asylum, citizenship or lack thereof. Depending on these factors, some asylum-seekers may receive full healthcare services, whereas others may have only limited rights. The article shows that the migrant statuses created by national and EU law do not fit in the system of statuses in the Charter, which might produce legal hindrances to accessing health-related rights for asylum-seekers. The article also discusses the possible ways for the European Committee of Social Rights to further expand the scope of the Charter’s application.
Variable scintillation arcs of millisecond pulsars observed with the Large European Array for Pulsars
Authors: Main R A , Antoniadis J , Chen S , Cognard I , Hu H , Jang J , Karuppusamy R , Kramer M , Liu K , Liu Y , Mall G , McKee J W , Mickaliger M B , Perrodin D , Sanidas S A , Stappers B W , Sprenger T , Wucknitz O , Bassa C G , Burgay M , Concu R , Gaikwad M , Janssen G H , Lee K J , Melis A , Pilia M , Possenti A , Wang L , Zhu W W 
Published: July 2023

ABSTRACT
We present the first large sample of scintillation arcs in millisecond pulsars (MSPs), analysing 12 sources observed with the Large European Array for Pulsars (LEAP), and the Effelsberg 100-m telescope. We estimate the delays from multipath propagation, measuring significant correlated changes in scattering time-scales over a 10 yr time span. Many sources show compact concentrations of power in the secondary spectrum, which in PSRs J0613−0200 and J1600−3053 can be tracked between observations, and are consistent with compact scattering at fixed angular positions. Other sources such as PSRs J1643−1224 and J0621+1002 show diffuse, asymmetric arcs which are likely related to phase-gradients across the scattering screen. PSR B1937+21 shows at least three distinct screens which dominate at different times and evidence of varying screen axes or multiscreen interactions. We model annual and orbital arc curvature variations in PSR J0613−0200, providing a measurement of the longitude of ascending node, resolving the sense of the orbital inclination, where our best-fit model is of a screen with variable axis of anisotropy over time, corresponding to changes in the scattering of the source. Unmodelled variations of the screen’s axis of anisotropy are likely to be a limiting factor in determining orbital parameters with scintillation, requiring careful consideration of variable screen properties, or independent very long baseline interferometry (VLBI) measurements. Long-term scintillation studies such as this serve as a complementary tool to pulsar timing, to measure a source of correlated noise for pulsar timing arrays, solve pulsar orbits, and to understand the astrophysical origin of scattering screens.
Identifying the SN 2022acko progenitor with JWST
Authors: Van Dyk Schuyler D , Bostroem K Azalee , Zheng WeiKang , Brink Thomas G , Fox Ori D , Andrews Jennifer E , Filippenko Alexei V , Dong Yize , Hoang Emily , Hosseinzadeh Griffin , Janzen Daryl , Jencson Jacob E , Lundquist Michael J , Meza Nicolas , Milisavljevic Dan , Pearson Jeniveve , Sand David J , Shrestha Manisha , Valenti Stefano , Howell D Andrew 
Published: July 2023

ABSTRACT
We report on analysis using the JWST to identify a candidate progenitor star of the Type II-plateau (II-P) supernova SN 2022acko in the nearby, barred spiral galaxy NGC 1300. To our knowledge, our discovery represents the first time JWST has been used to localize a progenitor system in pre-explosion archival Hubble Space Telescope (HST) images. We astrometrically registered a JWST NIRCam image from 2023 January, in which the SN was serendipitously captured, to pre-SN HST F160W and F814W images from 2017 and 2004, respectively. An object corresponding precisely to the SN position has been isolated with reasonable confidence. That object has a spectral energy distribution (SED) and overall luminosity consistent with a single-star model having an initial mass possibly somewhat less than the canonical 8 M⊙ theoretical threshold for core collapse (although masses as high as 9 M⊙ for the star are also possible); however, the star’s SED and luminosity are inconsistent with that of a super-asymptotic giant branch star that might be a forerunner of an electron-capture SN. The properties of the progenitor alone imply that SN 2022acko is a relatively normal SN II-P, albeit most likely a low-luminosity one. The progenitor candidate should be confirmed with follow-up HST imaging at late times, when the SN has sufficiently faded. This potential use of JWST opens a new era of identifying SN progenitor candidates at high spatial resolution.
The second set of pulsar discoveries by CHIME/FRB/Pulsar: 14 rotating radio transients and 7 pulsars
Authors: Dong Fengqiu Adam , Crowter Kathryn , Meyers Bradley W , Pleunis Ziggy , Stairs Ingrid , Tan Chia Min , Yu Tinyau Timothy , Boyle Patrick J , Cook Amanda M , Fonseca Emmanuel , Gaensler B M , Good Deborah C , Kaspi Victoria , McKee James W , Patel Chitrang , Pearlman Aaron B 
Published: July 2023

ABSTRACT
The Canadian Hydrogen Mapping Experiment (CHIME) is a radio telescope located in British Columbia, Canada. The large field of view allows CHIME/FRB to be an exceptional pulsar and rotating radio transient (RRAT) finding machine, despite saving only the metadata of incoming Galactic events. We have developed a pipeline to search for pulsar/RRAT candidates using density-based spatial clustering of applications with noise (dbscan), a clustering algorithm. Follow-up observations are then scheduled with the more sensitive CHIME/Pulsar instrument capable of near-daily high-time resolution spectra observations. We have developed the CHIME/Pulsar Single Pulse Pipeline to automate the processing of CHIME/Pulsar search-mode data. We report the discovery of 21 new Galactic sources, with 14 RRATs, 6 isolated long-period pulsars, and 1 binary system. Owing to CHIME/Pulsar’s observations, we have obtained timing solutions for 8 of the 14 RRATs along with all the regular pulsars and the binary system. Notably, we report that the binary system is in a long orbit of 412 d with a minimum companion mass of 0.1303 solar masses and no evidence of an optical companion within 10″ of the pulsar position. This highlights that working synergistically with CHIME/FRB’s large survey volume CHIME/Pulsar can obtain arc second localizations for low-burst rate RRATs through pulsar timing. We find that the properties of our newly discovered RRATs are consistent with those of the presently known population. They tend to have lower burst rates than those found in previous surveys, which is likely due to survey bias rather than the underlying population.
Finding LoTSS of hosts for GRBs: a search for galaxy–gamma-ray burst coincidences at low frequencies with LOFAR
Authors: Eyles-Ferris R A J , Starling R L C 
Published: July 2023

ABSTRACT
The LOFAR (Low Frequency Array) Two-metre Sky Survey (LoTSS) is an invaluable new tool for investigating the properties of sources at low frequencies and has helped to open up the study of galaxy populations in this regime. In this work, we perform a search for host galaxies of gamma-ray bursts (GRBs). We use the relative density of sources in Data Release 2 (DR2) of LoTSS to define the probability of a chance alignment, Pchance, and find 18 sources corresponding to 17 GRBs that meet a Pchance &lt; 1 per cent criterion. We examine the nature and properties of these radio sources using both LOFAR data and broad-band information, including their radio spectral index, star formation rate estimates, and any contributions from active galactic nucleus emission. Assuming that the radio emission is dominated by star formation, we find that our sources show high star formation rates (101–103 M⊙ yr−1) compared with both a field galaxy sample and a sample of core-collapse supernova hosts, and the majority of putative hosts are consistent with ultra-luminous infrared galaxy classifications. As a result of our analyses, we define a final sample of eight likely GRB host candidates in the LoTSS DR2 survey.
A sample of fast radio bursts discovered and localized with MeerTRAP at the MeerKAT telescope
Authors: Jankowski F , Bezuidenhout M C , Caleb M , Driessen L N , Malenta M , Morello V , Rajwade K M , Sanidas S , Stappers B W , Surnis M P , Barr E D , Chen W , Kramer M , Wu J , Buchner S , Serylak M , Prochaska J Xavier 
Published: July 2023

ABSTRACT
We present a sample of well-localized fast radio bursts (FRBs) discovered by the MeerTRAP project at the MeerKAT telescope in South Africa. We discovered the three FRBs in single coherent tied-array beams and localized them to an area of ∼1 arcmin2. We investigate their burst properties, scattering, repetition rates, and localizations in a multiwavelength context. FRB 20201211A shows hints of scatter broadening but is otherwise consistent with instrumental dispersion smearing. For FRB 20210202D, we discovered a faint post-cursor burst separated by ∼200 ms, suggesting a distinct burst component or a repeat pulse. We attempt to associate the FRBs with host galaxy candidates. For FRB 20210408H, we tentatively (0.35–0.53 probability) identify a compatible host at a redshift ∼0.5. Additionally, we analyse the MeerTRAP survey properties, such as the survey coverage, fluence completeness, and their implications for the FRB population. Based on the entire sample of 11 MeerTRAP FRBs discovered by the end of 2021, we estimate the FRB all-sky rates and their scaling with the fluence threshold. The inferred FRB all-sky rates at 1.28 GHz are $8.2_{-4.6}^{+8.0}$ and $2.1_{-1.1}^{+1.8} \times 10^3 \: \text{sky}^{-1} \: \text{d}^{-1}$ above 0.66 and 3.44 Jy ms for the coherent and incoherent surveys, respectively. The scaling between the MeerTRAP rates is flatter than at higher fluences at the 1.4σ level. There seems to be a deficit of low-fluence FRBs, suggesting a break or turn-over in the rate versus fluence relation below 2 Jy ms. We speculate on cosmological or progenitor-intrinsic origins. The cumulative source counts within our surveys appear consistent with the Euclidean scaling.
Rotation measure variations in Galactic Centre pulsars
Authors: Abbate F , Noutsos A , Desvignes G , Wharton R S , Torne P , Kramer M , Eatough R P , Karuppusamy R , Liu K , Shao L , Wongphechauxsorn J 
Published: July 2023

ABSTRACT
We report the results of an observational campaign using the Effelsberg 100-m telescope of the pulsars J1746−2849, J1746−2850, J1746−2856, and J1745−2912 located in the central molecular zone (CMZ) close to the Galactic Centre in order to study rotation measure (RM) variations. We report for the first time the RM value of PSR J1746−2850 to be −12234 ± 181 rad m−2. This pulsar shows significant variations of RM of 300–400 rad m−2 over the course of months to years that suggest a strongly magnetized environment. The structure function analysis of the RM of PSR J1746−2850 revealed a steep power-law index of $1.87_{-0.3}^{+0.4}$ comparable to the value expected for isotropic turbulence. This pulsar also showed large dispersion measure (DM) variation of ∼50 pc cm−3 in an event lasting a few months where the RM increased by ∼200 rad m−2. The large difference in RM between PSR J1746−2849 and PSR J1746−2850 despite the small angular separation reveals the presence of a magnetic field of at least 70 μG in the CMZ and can explain the lack of polarization in the radio images of the region. These results contribute to our understanding of the magnetic field in the CMZ and show similarities between the RM behaviours of these pulsars and some fast radio bursts.
Hα kinematics of superbubbles and supernova remnants of the dwarf galaxy NGC 4214
Authors: Sánchez-Cruces M , Rosado M 
Published: July 2023

ABSTRACT
We analysed the ionized gas kinematics of the dwarf galaxy NGC 4214 using high resolution Fabry–Perot interferometry observations and present a set of narrowband images in the Hα, [S ii] λ6717 Å, [N ii] λ6584 Å, and [O iii] λ5007 Å emission lines. The high-resolution Fabry–Perot observations of the Hα emission line, allowed us to derive the velocity field, the velocity dispersion σ, and the rotation curve of the galaxy. We also present for the first time, 3D kinematic maps of the complexes NGC 4214-I and NGC 4214-II and analysed the kinematics of the ionized gas of two new superbubbles, as well as the supernova remnants previously detected in this galaxy by other authors, in radio, optical, and X-ray emission. We computed the expansion velocities of the superbubbles and supernova remnants fitting their velocity profiles and obtained their respective physical parameters. We found that the superbubbles have an expansion velocity of ∼50 km s −1, dynamical age about ∼2 Myr and wind luminosity LW of ∼9 × 1038 erg s−1 produced probably by massive stars in OB associations. For supernova remnants, their expansion velocities are between ∼48 and ∼80 km s−1 with ages of about 104 yr and kinetic energy of about 1051 erg assuming they are in the radiative phase of evolution.
Active galactic nuclei feedback in an elliptical galaxy (III): the impacts and fate of cosmological inflow
Authors: Zhu Bocheng , Yuan Feng , Ji Suoqing , Peng Yingjie , Ho Luis C , Ostriker Jeremiah P , Ciotti Luca 
Published: July 2023

ABSTRACT
The cosmological inflow of a galaxy is speculated to be able to enter the galaxy and enhance the star formation rate (SFR) and black hole accretion rate (BHAR). In this paper, by performing high-resolution hydrodynamic simulations in the framework of macer, we investigate the fate of the inflow and its impacts on the evolution of a massive elliptical galaxy. The inflow properties are adopted from the cosmological simulation IllustrisTNG. We find that the inflow gas hardly enters but is blocked beyond ∼20 kpc from the central galaxy and becomes part of the circumgalactic medium (CGM). The gas pressure gradient, mainly contributed by the thermalized stellar wind and subdominant contributed by the energy input from the active galactic nuclei (AGNs), balances gravity and prevents the inflow from entering the galaxy. The SFR and BHAR are almost not affected by the normal inflow. However, if the rate of cosmological inflow were increased by a factor of 3, a small fraction of the inflow would enter the galaxy and contribute about 10 per cent of the gas in the galaxy. In this case, the gas density in the galaxy would increase by a factor of $\gtrsim$20. This increase is not because of the additional gas supply by the inflow but due to the increase of gas density and pressure in the CGM caused by the inflow. Consequently, the SFR and BHAR would increase by a factor of ∼5 and ∼1000, respectively. Finally, AGN feedback can perturb the motion of the inflow and heat the CGM through its intermittent outbursts.
Mining for a new class of fungal natural products: the evolution, diversity, and distribution of isocyanide synthase biosynthetic gene clusters
Authors: Nickles Grant R , Oestereicher Brandon , Keller Nancy P , Drott Milton T 
Published: July 2023

Abstract
The products of non-canonical isocyanide synthase (ICS) biosynthetic gene clusters (BGCs) mediate pathogenesis, microbial competition, and metal-homeostasis through metal-associated chemistry. We sought to enable research into this class of compounds by characterizing the biosynthetic potential and evolutionary history of these BGCs across the Fungal Kingdom. We amalgamated a pipeline of tools to predict BGCs based on shared promoter motifs and located 3800 ICS BGCs in 3300 genomes, making ICS BGCs the fifth largest class of specialized metabolites compared to canonical classes found by antiSMASH. ICS BGCs are not evenly distributed across fungi, with evidence of gene-family expansions in several Ascomycete families. We show that the ICS dit1/2 gene cluster family (GCF), which was prior only studied in yeast, is present in ∼30% of all Ascomycetes. The dit variety ICS exhibits greater similarity to bacterial ICS than other fungal ICS, suggesting a potential convergence of the ICS backbone domain. The evolutionary origins of the dit GCF in Ascomycota are ancient and these genes are diversifying in some lineages. Our results create a roadmap for future research into ICS BGCs. We developed a website (https://isocyanides.fungi.wisc.edu/) that facilitates the exploration and downloading of all identified fungal ICS BGCs and GCFs.