bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diagnosis and management of post-COVID (Long COVID) in children: a moving target
Authors: Morello Rosa , Martino Laura , Buonsenso Danilo 
Published: January 2023

Purpose of review
This review describes recent findings about post-COVID condition (PCC, or Long COVID) in children, including current knowledge about its epidemiology, clinical presentation, pathogenesis and care.

Recent findings
There is no internationally agreed definition of PCC, although now most researchers agree that it is a complex clinical symptomatology persisting for at least 3 months after COVID-19, without an alternative diagnosis. There are several uncertainties about paediatric PCC. So far, available literature suggest that 1–3% of recognized children with Severe Acute Respiratory Syndrome COronaVirus 2 (SARS-CoV-2) infection may develop PCC. Its pathogenesis is unknown, although there is increasing evidence about possible abnormalities in the immune responses, cellular metabolism and intestinal microbiota, along with chronic endothelitis.

Summary
Management of PCC in children is complex and require a multidisciplinary approach, with the goal of offering the best care possible to support diagnostics, research, mental health and access to research projects.
Discharge Delay
Authors: Armold Sarah 
Published: January 2023

Purpose/Objectives:
Discharge delays are frustrating to patients, staff, and families. Case managers need a better understanding of what type of patient may experience a discharge delay so they can better prepare patients and families or avoid the discharge delay before it happens.

Primary Practice Setting(s):
Hospital.

Findings/Conclusions:
Discharge delays are exasperating to all involved, as they take up precious time and resources of case managers and make patients and families feel like there is an unclear plan. There are actions a case manager can take to lessen the burden of a discharge delay. Actions such as having a rapid discharge plan once the home environment is deemed inappropriate and making sure families and patients are communicated with frequently about their plan of care can decrease or avoid a discharge delay.

Implications for Case Management Practice:
Case managers need to know how to identify a patient who might experience a delay in their discharge early, so they can assist the patient and family to ease their stress by explaining limitations and realistic timelines. By identifying a patient who will be experiencing a delay in their discharge due to postacute lack of staffing, care managers can alert families that finding other options for discharge might be more satisfactory. By screening a patient and identifying their needs early, a discharge delay can be shortened or avoided.
Extracorporeal Membrane Oxygenation in Pediatric Acute Respiratory Distress Syndrome: From the Second Pediatric Acute Lung Injury Consensus Conference
Authors: Rambaud Jérome , Barbaro Ryan P. , Macrae Duncan J. , Dalton Heidi J. ,   on behalf of the Second Pediatric Acute Lung Injury Consensus Conference (PALICC-2) of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network
Published: January 2023

OBJECTIVES:
To systematically review and assimilate literature on children receiving extracorporeal membrane oxygenation (ECMO) support in pediatric acute respiratory distress syndrome (PARDS) with the goal of developing an update to the Pediatric Acute Lung Injury Consensus Conference recommendations and statements about clinical practice and research.

DATA SOURCES:
Electronic searches of MEDLINE (Ovid), Embase (Elsevier), and CINAHL Complete (EBSCOhost).

STUDY SELECTION:
The search used a medical subject heading terms and text words to capture studies of ECMO in PARDS or acute respiratory failure. Studies using animal models and case reports were excluded from our review.

DATA EXTRACTION:
Title/abstract review, full-text review, and data extraction using a standardized data collection form.

DATA SYNTHESIS:
The Grading of Recommendations Assessment, Development, and Evaluation approach was used to identify and summarize evidence and develop recommendations. There were 18 studies identified for full-text extraction. When pediatric data was lacking, adult and neonatal data from randomized clinical trials and observational studies were considered. Six clinical recommendations were generated related to ECMO indications, initiation, and management in PARDS. There were three good practice statements generated related to ECMO indications, initiation, and follow-up in PARDS. Two policy statements were generated involving the impact of ECMO team organization and training in PARDS. Last, there was one research statement.

CONCLUSIONS:
Based on a systematic literature review, we propose clinical management, good practice and policy statements within the domains of ECMO indications, initiation, team organization, team training, management, and follow-up as they relate to PARDS.
Depression and PTSD as Predictors of Attrition in Older Adult Exercise Programs
Authors: Ha Anh , Wilkins Stacy Schantz , Melrose Rebecca J. , Lee Cathy C. 
Published: January 2023

Background:
In older adults, exercise is extremely important and has been demonstrated to improve physical health, cognition, and mood. However, attrition in exercise programs in general is high, with up to 50% of participants leaving in the first 3 to 6 months.

Methods:
A systematic review of PubMed and PsycINFO databases was conducted using PRISMA criteria assessing the association of baseline depression and/or posttraumatic stress disorder (PTSD) with attrition rates in older adult exercise programs.

Results:
Ten articles were identified that assessed baseline depression and attrition in older adult exercise programs. No studies assessed baseline PTSD as a risk for attrition. Attrition rate overall ranged from 19% to 38%, and depression at baseline was found to be significantly associated with higher attrition rates. Other factors associated with attrition included anxiety, lower life satisfaction, worse cognitive health, higher illness rating, shorter program duration, common illnesses, lower social support, male sex, single relationship status, and transportation dependence.

Discussion:
Depression at baseline was significantly related with increased attrition in older adult exercise programs. Screening and consideration of adjunctive mood treatment are recommended. Further study of PTSD as an attrition risk is recommended, particularly in veteran or other populations with greater base rates.
The complete chloroplast genome sequence ofAkebia trifoliataand a comparative analysis within the Ranales clade
Authors: Wang Ruixian , Chu Qu , Meng Gang , Li Chuan 
Published: January 2023

AbstractThe complete nucleotide sequence of theAkebia trifoliatachloroplast (cp) genome was reported and characterized in this study. The cp genome is a closed circular molecule of 157 949 bp, composed of a pair of IR regions of 26 149 bp, one LSC region of 86 595 bp, and one SSC region of 19 056 bp. The GC contents of the LSC, SSC, and IR regions, and the whole cp genome are 37.11%, 33.62%, 43.08% and 38.66%, respectively. The cp genome contains 130 predicted functional genes, including 85PCGs of 79 107 bp, 37 tRNA and 8 rRNA genes of 11 851 bp. 168 SSRs and 23 long repeats were identified in the cp genome. The results revealed that 21 891 codons characterize the coding capacity of 85 protein-coding genes inAkebia trifoliata, 10.84% and 1.20% of the codons coded for leucine and cysteine respectively. The usage of the start codon exhibited no bias in theA. trifoliatacp genome. Phylogenetic analysis suggest thatA. trifoliatais most closely related toS. japonica, which then formed a cluster withN. dormesticaandM. saniculifoliato form subgroup of Ranunculales. Our study provides information on mangrove plant species in coastal intertidal zones.
The Lupus Epigenome Relates to Genetics, Transcription and Serological Profiles with Dependency on Molecular Subtypes and Informs Drug Discovery
Authors: Castellini-Pérez Olivia , Barturen Guillermo , Martínez-Bueno Manuel , Iakovliev Andrii , Kerick Martin , López-Domínguez Raúl , Marañón Concepción , Martín Javier , Ballestar Esteban ,   PRECISEADS Clinical Consortium,   PRECISEADS Flow Cytometry Study Group, Borghi María Orietta , Qiu Weiliang , Zhu Cheng , Shankara Srinivas , Spiliopoulou Athina , de Rinaldis Emanuele , Carnero-Montoro Elena , Alarcón-Riquelme Marta E. 
Published: January 2023

ABSTRACTObjectiveThe heterogeneity of systemic lupus erythematosus (SLE) can be explained by epigenetic alterations that disrupt transcriptional programs mediating environmental and genetic risk. This study evaluated the epigenetic contribution to SLE heterogeneity considering molecular and serological subtypes, genetics and transcriptional status, followed by drug target discovery.MethodsWe performed a stratified epigenome-wide association studies of whole blood DNA methylation from 213 SLE patients and 221 controls. Methylation quantitative trait loci analyses, cytokine and transcription factor activity - epigenetic associations and methylation-expression correlations were conducted. New drug targets were searched for based on differentially methylated genes.ResultsIn a stratified approach, a total of 974 differential methylation CpG sites with dependency on molecular subtypes and autoantibody profiles were found. Mediation analyses suggested that SLE-associated SNPs in the HLA region exert their risk through DNA methylation changes. Novel genetic variants regulating DNAm in disease or in specific molecular contexts were identified. The epigenetic landscapes showed strong association with transcription factor activity and cytokine levels, conditioned by the molecular context. Epigenetic signals were enriched in known and novel potential drug targets for SLE.ConclusionThis study expands the number of genes associated with SLE and reveals novel pathways of disease. The findings reveal possible genetic drivers and consequences of epigenetic variability on SLE heterogeneity and disentangles the DNAm mediation role on SLE genetic risk and the genetic architecture of DNAm in different molecular contexts. Finally, novel targets for drug development were discovered.
Building a prognostic tool for disorders of consciousness: protocol for a multimodal imaging study (IMAGINA study)
Authors: Maude Beaudoin-Gobert , Inès Merida , Nicolas Costes , Fabien Perrin , Nathalie André-Obadia , Frédéric Dailler , Carole Lartizien , Benjamin Riche , Delphine Maucort-Boulch , Jacques Luauté , Florent Gobert 
Published: January 2023

ABSTRACTBackgroundIn the last decades, advances in Intensive Care Unit management have led to decreased mortality. However, significant morbidity remains as patients survive after a lesional coma with uncertain quality of awakening and high risk of functional disability. Predicting this level of recovery but also the functional disability of those who will awake constitutes a major challenge for medical, ethical and social perspectives. Among the huge heterogeneity of coma-related injuries, recognising the universality of a common functional pattern which may be focused on a final step of an integrated network would be of great interest for our understanding of disorders of consciousness. The objective of this study is to investigate the neural correlates of arousal and awareness in coma and post-coma to build a prognostic tool based on the detection of a common pattern between patients with a favourableversusan unfavourable outcome.Method/DesignWe will implement this objective in a translational approach which combines PET-MR imaging, neurophysiology, behavioural/clinical assessments and innovative statistical and computational analysis tools in patients with disorders of consciousness in Intensive Care Unit and in Rehabilitation Department.
Scientific data management policy in China: a quantitative content analysis based on policy text
Authors: Si Li , Liu Li , He Yi 
Published: January 2023

PurposeThis paper aims to understand the current development situation of scientific data management policy in China, analyze the content structure of the policy and provide a theoretical basis for the improvement and optimization of the policy system.Design/methodology/approachChina's scientific data management policies were obtained through various channels such as searching government websites and policy and legal database, and 209 policies were finally identified as the sample for analysis after being screened and integrated. A three-dimensional framework was constructed based on the perspective of policy tools, combining stakeholder and lifecycle theories. And the content of policy texts was coded and quantitatively analyzed according to this framework.FindingsChina's scientific data management policies can be divided into four stages according to the time sequence: infancy, preliminary exploration, comprehensive promotion and key implementation. The policies use a combination of three types of policy tools: supply-side, environmental-side and demand-side, involving multiple stakeholders and covering all stages of the lifecycle. But policy tools and their application to stakeholders and lifecycle stages are imbalanced. The development of future scientific data management policy should strengthen the balance of policy tools, promote the participation of multiple subjects and focus on the supervision of the whole lifecycle.Originality/valueThis paper constructs a three-dimensional analytical framework and uses content analysis to quantitatively analyze scientific data management policy texts, extending the research perspective and research content in the field of scientific data management. The study identifies policy focuses and proposes several strategies that will help optimize the scientific data management policy.
The role of director incentives in investment efficiency
Authors: Zhang Yan , Michael Michael 
Published: January 2023

Purpose
The existing literature involving director compensation has been concentrating on its absolute or intrinsic values. Although the relevant studies have generated mixed findings, research in other fields suggests that the power of an incentive may be determined by its value relative to the chosen referencing standard more than its absolute value. This study aims to investigate how relative director pay affects corporate investment efficiency.

Design/methodology/approach
This study takes a fresh theoretical viewpoint by framing the investigation using the dimensional comparison theory and proposing that a directorship also presents a relative value that may influence the board’s performance. Ordinary least squared regressions and two-stage system generalised method of moments are used to analyse 14,267 firm-year observations.

Findings
The empirical results suggest that the relative director pay is a better estimate of the power of the incentive than the absolute pay. A positive association between the relative director pay and investment efficiency is evident, while the absolute pay has no significant effect on investment decisions. Director overcompensation, however, will cancel out the positive effect of director compensation on investment efficiency. Firms with relatively lower unexpected investment (UI) level benefit the most from an increase in the relative director pay, while neither absolute nor relative director pay affects investment choices in firms with a high UI level because of significantly more overcompensation.

Originality/value
To the best of the authors’ knowledge, this study is the first attempt to investigate the effect of relative director pay. It is also the first to examine the role of dimensional comparison in strategic decisions which is the single untended comparison framework in the director pay design. The current director pay structure has emphasised social and temporal equality by standardising the pay structure and vesting the equity-based pay over a long period. Yet it ignores the fact that people decide their commitment level by comparing the reward with an internal referent too. The findings speak to the dimensional comparison theory in that the inequality emanated from dimensional or internal comparison may be accentuated by the perceived equality in other comparison frameworks, driving the different performances in the roles one assumes.
Method for automating the processes of generating and using 4D BIM models integrated with location-based planning and Last Planner® System
Authors: Silveira Bruno Falcón , Costa Dayana Bastos 
Published: January 2023

Purpose
Several studies have addressed the use of four-dimensional (4D) building information modeling (BIM) for construction management. However, the automation of the processes for generating 4D models and their integrated use with Location-Based Planning and the Last Planner® System is not well discussed. Therefore, this paper aims to develop a method for automating the generation and use of 4D BIM models integrated with Location-Based Planning and Last Planner® System supporting project control cycles.

Design/methodology/approach
The research strategy adopted was Design Science Research. The automated method for using the 4D models was developed and refined in two residential building projects in Brazil, along with 31 meetings and involving 11 direct users. The assessment of the proposed method focuses on four constructs: the impact of process automation, the impact on the identification and assessment of site progress and the planning process, ease of adoption and utility of the proposed method.

Findings
The results of this paper indicated increased adherence between planned and executed through an automated method for using the 4D models. The established routines enabled automating the link between the planning levels and the three-dimensional (3D) model, providing a more agile and updated data source and achieving 92.8% of user satisfaction regarding the deadline and frequency of delivery of the 4D model reports. Moreover, this study identified the relationships between the processes of the method proposed and Digital Models.

Originality/value
The primary scientific value achieved in this study is creating a method for automating processes and simplifying steps for the generation and use of 4D BIM models in the production planning and control cycles during the construction phase.
Understanding gender differences in money attitudes: biological and psychological gender perspective
Authors: Sahi Shalini Kalra 
Published: January 2023

PurposeVarious research studies in the past have found biological gender to be a differentiator for money attitudes. However, the beliefs and attitudes that people have towards money can also be the result of the gender socialisation, which may have a greater impact on how one relates to money. Since, gender is an important aspect for understanding financial choices and decisions, it becomes pertinent to learn as to which aspect of gender, the biological or the psychological, impact the money attitudes and beliefs that a person holds. The purpose of this paper is to address this issue.Design/methodology/approachThis empirical work attempts to understand gender differences in money attitudes from the biological gender and psychological gender perspective. The Bem Sex Role Inventory (BSRI) and Tang's money ethic scale (MES) were used for this study. The hypotheses raised were tested on a sample of 224 respondents from India.FindingsThe results suggested that money attitudes can be better understood when seen from the lens of psychological gender and not biological gender. Further, androgyny individuals were found to exhibit more balance in their money attitude dimensions than masculine or feminine individuals.Originality/valueBelief and attitudes towards money would impact how contented people are with the compensation they receive, their financial planning choices and also their financial well-being. This insightful study adds to the scant literature that exists on understanding money attitudes from psychological gender perspective and would pave the way for more work in this area.
Portfolios of sustainable practices for packaging in the circular economy: an analysis of Italian firms
Authors: Cozzolino Alessandra , De Giovanni Pietro 
Published: January 2023

PurposeThis study analyzes sustainable practices adopted by Italian firms to enhance the circularity of packaging and related results in terms of environmental improvements.Design/methodology/approachThe authors developed an empirical analysis using publicly available data from the National Consortium of Packaging (CONAI) in Italy, which consists of 603 circular packaging projects. The authors ran both descriptive and prescriptive analyses to determine individual sustainable practices and portfolios adopted to enhance packaging circularity and to verify related reductions in terms of CO2 emissions as well as energy usage and water consumption.FindingsThe findings reveal that firms are more accustomed to focusing on single sustainable practices than on portfolios of practices to achieve packaging circularity. Raw material saving and logistics optimization are the most frequent sustainable practices adopted by firms to improve circularity of packaging. The reuse of packaging allows firms to simultaneously reduce CO2 emissions, energy usage and water consumption. Preferences in terms of portfolio of sustainable practices are strictly linked to the types of materials used for packaging and environmental targets.Originality/valueThe authors investigate environmental practices that firms adopt to support packaging circularity, and the authors detect portfolios of sustainable practices that positively impact environmental performance indicators. This research extends a significant glimpse into the portfolio of sustainable practices for packaging in the circular economy implemented by firms, filling academic gaps and indicating business opportunities and avenues for economic development.
How insights from the field of information behavior can enrich understanding of knowledge mobilization
Authors: Nicolini Davide , Korica Maja , Bharatan Ila 
Published: January 2023

PurposeThe authors review the literature on information behavior, an autonomous body of work developed mainly in library studies and compare it with work on knowledge mobilization. The aim is to explore how information behavior can contribute to understanding knowledge mobilization in healthcare management.Design/methodology/approachThe authors conducted a narrative review using an exploratory, nonkeyword “double-sided systematic snowball” method. This is especially useful in the situation when the two traditions targeted are broad and relies on distinct vocabulary.FindingsThe authors find that the two bodies of work have followed similar trajectories and arrived at similar conclusions, with a linear view supplemented first by a social approach and then by a sensitivity to practice. Lessons from the field of information behavior can be used to avoid duplication of effort, repeating the same errors and reinventing the wheel among knowledge translation scholars. This includes, for example, focusing on sources of information or ignoring the mundane activities in which managers and policymakers are involved.Originality/valueThe study is the first known attempt to build bridges between the field of information behavior and the study of knowledge mobilization. The study, moreover, foregrounds the need to address knowledge mobilization in context-sensitive and social rather than technical terms, focusing on the mundane work performed by a variety of human and nonhuman agents.