bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors influencing postpartum depression among Japanese parents: A prospective longitudinal study
Authors: Yamakawa Yuko , Maruta Michio , Higuchi Yuya , Tokunaga Akiko , Iwanaga Ryoichiro , Honda Sumihisa , Imamura Akira , Tanaka Goro 
Published: March 2023

AbstractAimPostpartum depression (PPD) may have negative effects on the parents and lead to impaired cognitive, socioemotional, and behavioral development in their children. The purpose of this study was to examine factors associated with PPD in parents during the first year after delivery.MethodsThis study used a self‐administered questionnaire. Questionnaires were mailed at 5 days, 3 months, 6 months, and 1 year after delivery, respectively. The particpants were 107 pairs of mothers and fathers. PPD was assessed using the Edinburgh Postnatal Depression Scale (EPDS). Data on sense of coherence (SOC), Quality Marriage Index, Social Support Scale, Mother‐to‐Infant Bonding Scale, and sociodemographic variables were collected. Multiple regression analysis was performed to examine the strength of the association between several variables and the EPDS at each survey period for fathers and mothers, respectively.ResultsThe prevalence of PPD in the first‐year postpartum ranged from 12.1%–23.4% to 7.5%–8.4% for fathers and mothers, respectively. SOC had the strongest impact on EPDS scores for both fathers and mothers at all four survey periods.ConclusionsOur findings suggest that stress coping skills are an important factor affecting PPD throughout the first‐year postpartum for both fathers and mothers.
Relationship between tumor thickness on images and cellular dissociation grading composing of tumor budding and cell nest size in early tongue cancer
Authors: Yokoo Yoshinobu , Yuasa Kenji , Ohno Jun , Ikebe Tetsuro 
Published: March 2023

AbstractPurposeThe purpose of this study is to clarify whether the image analysis using contrast enhanced CT, contrast enhanced T1‐weighted MR imaging and ultrasonography (US), is related with the cellular dissociation grade (CDG) based on tumor budding grade and cell nest size in stage I and II tongue oral squamous cell carcinoma (OSCC).MethodSeventeen cases of T1N0M0 and T2N0M0 tongue OSCC with the completion of more than 1‐year follow‐up were retrospectively enrolled. The satisfactory data, including contrast enhanced CT images, contrast enhanced T1‐weighted MR images, and US images as well as histopathological specimens could be taken from 16 cases and analyzed by the specialists of oral pathologist, oral radiologist, and oral and maxillofacial surgeon.ResultsThe differences between tumor thickness (TT) on US images and TT on contrast enhanced CT images or contrast enhanced T1‐weighted MR images were larger in the lower tumor budding grade cases rather than in the higher budding grade. Likely, such image‐measured TT differences were larger in the bigger nest cases than in the smaller nest cases. The occurrence of delayed nodal metastasis was related to the small TT differences of CT–US or MRI–US and the higher CDG score (≧5 points). All the cases with delayed nodal metastasis were CDG score ≧5 points.ConclusionsTT differences between on contrast enhanced CT/MR imaging, and US imaging may predict the cell dissociation activity and nodal metastasis.
Efficacy and safety of pharmacological interventions for managing sickle cell disease complications in children and adolescents: Systematic review with network meta‐analysis
Authors: Tonin Fernanda S. , Ginete Catarina , Ferreira Joana , Delgadinho Mariana , Santos Brígida , Fernandez‐Llimos Fernando , Brito Miguel 
Published: March 2023

AbstractThis study aimed to synthesize the evidence on the effects of disease‐modifying agents for managing sickle cell disease (SCD) in children and adolescents by means of a systematic review with network meta‐analyses, surface under the cumulative ranking curve (SUCRA) and stochastic multicriteria acceptability analyses (SMAA) (CRD42022328471). Eightteen randomized controlled trials (hydroxyurea [n = 7], l‐arginine [n = 3], antiplatelets [n = 2], immunotherapy/monoclonal antibodies [n = 2], sulfates [n = 2], docosahexaenoic acid [n = 1], niprisan [n = 1]) were analyzed. SUCRA and SMAA demonstrated that hydroxyurea at higher doses (30 mg/kg/day) or at fixed doses (20 mg/kg/day) and immunotherapy/monoclonal antibodies are more effective for preventing vaso‐occlusive crisis (i.e., lower probabilities of incidence of this event; 14, 25, and 30%, respectively), acute chest syndrome (probabilities ranging from 8 to 30%), and needing of transfusions (11–31%), while l‐arginine (100–200 mg/kg) and placebo were more prone to these events. Therapies were overall considered safe; however, antiplatelets and sulfates may lead to more severe adverse events. Although the evidence was graded as insufficient and weak, hydroxyurea remains the standard of care for this population, especially if a maximum tolerated dose schedule is considered.
Plasma‐enhanced evaporation and its impact on plasma properties and gaseous chemistry in a pin‐to‐water pulsed discharge
Authors: Yang Qi , Qiao Jun‐Jie , Cheng He , Wang Da‐Zhi , Zhang Qing‐Yuan , Wang Xue‐Ying , Xiong Qing 
Published: March 2023

AbstractThe plasma in contact with liquids has led to various novel applications such as plasma biomedicine, material synthesis, and so on. However, the phenomenon of evaporation under plasma treatment and its impact on plasma–liquid interactions has a limited understanding. In this study, the spatially and temporally resolved behavior of water vapor production and its induced influences on plasma properties and gaseous chemistry were studied in detail in an atmospheric pressure pin‐to‐water pulsed He discharge. Diagnostic methods such as laser‐induced fluorescence (LIF) and high‐resolution optical emission spectroscopy (OES) were applied to determine the water vapor and OH radical densities, as well as key plasma parameters such as the gas temperature and electron density. It shows that the physicochemical properties of plasma vary among different discharge regions due to evaporation behavior stimulated during the pulsed discharge‐on phase. In addition, using simulation based on the experimental data, the mechanisms of how water vapor affects the observed spatiotemporal behaviors of OH radicals in different discharge regions are understood. Compared to the pin‐anode and liquid‐cathode sheath regions, proper electron parameters such as density and temperature, as well as water vapor density in the plasma‐positive column, significantly enhance the production of reactive OH radical through the dominant path of electron‐stimulated H2O dissociation. However, higher levels of electron parameters in the intense discharge region near the positive‐pin boundary enhance OH dissociation and finally result in the hollow distribution of OH density. From the global kinetic plasma simulation, the production of reactive hydroxide species playing key roles in plasma medicine treatments, such as O, H, HO2, H2O2, and hydrated ions including H+(H2O)4 and H+(H2O)5, are promoted noticeably as a result of the enhanced water evaporation process.
Exploring boron applications in modern agriculture: Antifungal activities and mechanisms of phenylboronic acid derivatives
Authors: Du Sha‐Sha , Luo Xiong‐Fei , An Jun‐Xia , Zhang Zhi‐Jun , Zhang Shao‐Yong , Wang Yi‐Rong , Ding Yan‐Yan , Jiang Wei‐Qi , Zhang Bao‐Qi , Ma Yue , Zhou Yong , Hu Yong‐Mei , Liu Ying‐Qian 
Published: March 2023

AbstractBackgroundThe unreasonable use of chemical fungicides causes common adverse consequences that not only affect the environment, but also cause resistance and resurgence problems of plant pathogens, which are extremely harmful to human health, the economy, and the environment. Based on the rich biological activities of boron‐based compounds, 82 phenylboronic acid derivatives were selected and their antifungal activities against six agricultural plant pathogens were determined. Combined with transcriptomics tools, the mechanism of action of compound A49 (2‐chloro‐5‐trifluoromethoxybenzeneboronic acid) against Botrytis cinerea Pers (B. cinerea) was studied.ResultsThe EC50 values of compounds A24, A25, A30, A31, A36, A41, A49 and B23 against all six fungi were under 10 μg/mL. Compound A49 displayed significant activity against B. cinerea (EC50 = 0.39 μg/mL), which was better than that of commercial fungicide boscalid (EC50 = 0.55 μg/mL). A49 not only inhibited the germination of B. cinerea spores, but also caused abnormal cell morphology, loss of cell membrane integrity, enhanced cell membrane permeability, and accumulation of intracellular reactive oxygen species. Further findings showed that A49 reduced cellular antioxidant activity, and peroxidase and catalase activities. Transcriptomic results indicated that A49 could degrade intracellular redox processes and alter the metabolism of some amino acids. Meanwhile, A49 showed obvious activity in vivo and low cytotoxicity to mammal cells.ConclusionThe boron‐containing small molecule compounds had high efficiency and broad‐spectrum antifungal activities against six plant pathogens, and are expected to be candidate compounds for a new class of antifungal drugs. © 2023 Society of Chemical Industry.
Science education in an age of misinformation
Authors: Osborne Jonathan , Pimentel Daniel 
Published: March 2023

AbstractIn this paper, we argue that the current science curricula are failing to educate students to be competent outsiders to science. Historically, science education has rested on two premises. The first is that it is possible for students to acquire sufficient scientific knowledge from K‐12 education to become intellectually independent. That is that science education can produce individuals capable of evaluating scientific evidence and arguments critically for themselves. This belief is what underlies many of the conceptions of scientific literacy and is the basis of the rationale that is used to sustain and justify what is offered in nearly all countries across the globe. The second is the belief that the science that students will encounter will have been filtered such that it can be trusted. Nothing today could be further from the truth. Today, misinformation abounds and much of it purports to be scientific. Very few conceptions of scientific literacy have considered how students can be prepared to evaluate the claims that abound on social media. Current conceptions of “scientific literacy,” we argue, are failing to articulate the competencies and knowledge required in today's changed context. In what follows, we lay out our arguments for why it is time to rethink the conception of scientific literacy by considering what it requires to be a competent outsider to science. Then drawing on our recent report, we lay out what might be done within science education to address the specific phenomenon of misinformation.
Theoretical study on the solvent‐free self‐catalyzed coupling mechanism of a chiral vicinal diamine and isobutyraldehyde mediated by the outgrowth H2O
Authors: Cheng Xueli , Zhao Yanyun , Liu Jingjing , Sun Junshan , Miao Yanfei , Ling Baoping 
Published: March 2023

AbstractThe self‐catalyzed addition of a chiral vicinal diamine with two isobutyraldehyde molecules and the subsequent diaza‐Cope rearrangement between two diimines were investigated systematically by M06‐2X method in conjunction with the 6‐311+G(d) basis set. Our theoretical model shows that, 1) the solvent‐free coupling of the vicinal diamine and isobutyraldehyde molecules produces a relative stable compounds with an imidazolidine‐dihydro‐1,3‐oxazine fused ring instead of imine intermediates; 2) the assistance of a yielded water molecule can significantly decrease the free‐energy barriers of the ring‐recombination and ring‐opening processes by borrowing a hydrogen atom from it; 3) the two addition processes with the free‐energy barriers of 150.0 and 159.0 kJ/mol, respectively, and the successive formation of the five‐membered ring with a barrier of 164.1 kJ/mol control the whole reaction system.
Comparative Studies of Co/SBA‐15 Catalysts Synthesized with Different Silica Sources Including Coal Fly Ash for Fischer‐Tropsch Synthesis
Authors: Gupta Pavan K. , Kumar Vineet , Maity Sudip , Kishore Gupta Goutam , Datta Sudipta , Singh Arvind , Sengupta Siddhartha 
Published: March 2023

AbstractSBA‐15 is synthesized using triblock copolymer Pluronic P123 as the structure directing agent and different silica sources such as tetraethyl orthosilicate (TEOS), sodium metasilicate, coal fly ash (CFA) derived supernatant and a mix of sodium metasilicate, CFA‐derived supernatant for comparative study towards Fischer‐Tropsch synthesis (FTS). The active metal cobalt (15 wt. %) has been impregnated in each support via the wet impregnation technique. The catalysts and supports are characterized by N2 adsorption‐desorption, Field Emission Scanning Electron Microscopy (FESEM), High‐Resolution Transmission Electron Microscopy (HRTEM), X‐ray Diffraction (XRD), X‐ray Energy Dispersion Spectrophotometer (EDX), Fourier Transform Infrared (FTIR), and Temperature Programmed Reduction (TPR). The catalytic performance of synthesized catalysts for the FTS has been investigated in a fixed bed tubular reactor at T=220 °C, P=30 bar, and GHSV=500 h−1 using simulated syngas composition equivalent to coal‐derived syngas using air blown fixed bed gasifier having H2/CO molar ratio of 2 : 1. The maximum CO conversion and middle distillate (C6−C20) selectivity is observed as 59.2 % and 84.6 % respectively for the catalyst support synthesized from mix of sodium metasilicate and CFA‐derived supernatant.
Aceclofenac Derivatives: Synthesis, Characterization, and Determination of Anti‐oxidant and Anti‐inflammatory Activities by Chemiluminescence Assays and Molecular Docking Studies
Authors: Raza Asim , Abbas Khan Mohsin , Ahmad Irshad , Bari Ahmad , Masood Anum , Ullah Farhat , Awan Breena 
Published: March 2023

AbstractAceclofenac (ACF) is a newer derivative of diclofenac, and one of the emerging NSAIDs for the treatment of various inflammatory diseases. In this research we have develop a set of 2‐(2‐(2‐((2,6‐dichlorophenyl)amino)phenyl)acetoxy)acetic acid derivatives (AR1‐AR12) using Fischer esterification in good yields and in an efficient manner. All the compounds were fully characterized physical (solubility and melting points) and chemical by spectral data analysis of FTIR, 1HNMR and 13CNMR and elemental analysis. In‐vitro anti‐inflammatory activity was performed by Chemiluminescence technique in which we found 2‐oxo‐1,2‐diphenylethyl2‐(2‐(2((2,6‐dichlorophenyl)amino)phenyl) acetoxy)acetate (AR2 71 %), 2‐(4‐formyl‐2‐methoxyphenoxy)‐2‐oxoethyl2‐(2‐((2,6 dichloro‐phenyl) amino)phenyl)acetate (AR3 74.7 %),2‐(2‐(2‐(2‐((2,6‐dichloropheny l)amino) phenyl) acetoxy) acetoxy)‐3‐(2‐(2‐(3‐((2,6‐dichlorophenyl) amino) phenyl) acetoxy)acetoxy)succinic acid (AR6 89.2 %), 2‐(4‐aminophenoxy)‐2‐oxoethyl2‐(2‐((2,6‐dichloro‐phenyl) amino) phenyl) acetate (AR8 71.1 %), 1,3‐dioxo‐2,3‐dihydro‐1H‐indene‐2,2‐diyl bis(2‐(2‐(2‐((2,6‐dichlorophenyl)amino)phenyl)acetoxy)acetate) (AR9 76.3 %) found more potent as compared to parent compound while AR3, AR6 and AR9 highly potent than standard reference ibuprofen (73.2 %). The current molecular docking study was performed In order to check the suitable method for the binding of target ligands and proteins Glide docking with extra precision (XP) mode. The hydrogen bonding interactions of Aceclofenac are prominent with Isoleucine moiety, those of compound AR‐6 shows hydrophobic interaction with active amino acid Leucine and Phenylalanine moieties. Anti‐oxidant activities were also performed, AR‐3 (79.30 %), AR‐5 (91.23 %), AR‐9 (83.43 %) AR‐12 (92.43 %) were found to be more anti‐oxidant as compared to aceclofenac (ACF) (66.46 %). These derivatives were synthesized with different aliphatic and aromatic alcohols and phenols.
Efficient Co‐Adsorption and Highly Selective Separation of Cs+ and Sr2+ with a K+‐Activated Niobium Germanate by the pH Control
Authors: Sun Hai‐Yan , Hu Bing , Lv Tian‐Tian , Guo Yan‐Ling , Yao Yue‐Xin , Yang Lu , Feng Mei‐Ling , Huang Xiao‐Ying 
Published: March 2023

Abstract137Cs and 90Sr are hazardous to ecological environment and human health due to their strong radioactivity, long half‐life, and high mobility. However, effective adsorption and separation of Cs+ and Sr2+ from acidic radioactive wastewater is challenging due to stability issues of material and the strong competition of protons. Herein, a K+‐activated niobium germanate (K‐NGH‐1) presents efficient Cs+/Sr2+ coadsorption and highly selective Cs+/Sr2+ separation, respectively, under different acidity conditions. In neutral solution, K‐NGH‐1 exhibits ultrafast adsorption kinetics and high adsorption capacity for both Cs+ and Sr2+ (qmCs = 182.91 mg g−1; qmSr = 41.62 mg g−1). In 1 M HNO3 solution, K‐NGH‐1 still possesses qmCs of 91.40 mg g−1 for Cs+ but almost no adsorption for Sr2+. Moreover, K‐NGH‐1 can effectively separate Cs+ from 1 M HNO3 solutions with excess competing Sr2+ and Mn+ (Mn+ = Na+, Ca2+, Mg2+) ions. Thus, efficient separation of Cs+ and Sr2+ is realized under acidic conditions. Besides, K‐NGH‐1 shows excellent acid and radiation resistance and recyclability. All the merits above endow K‐NGH‐1 with the first example of niobium germanates for radionuclides remediation. This work highlights the facile pH control approach towards bifunctional ion exchangers for efficient Cs+/Sr2+ coadsorption and selective separation.
Rationally Integrating 2D Confinement and High Sodiophilicity toward SnO2/Ti3C2Tx Composites for High‐Performance Sodium‐Metal Anodes
Authors: Li Zhipeng , Zhang Yiming , Guan Haotian , Meng Sikai , Lu Yangfan , Wang Jin , Huang Guangsheng , Li Xin , Cui Jingqin , Li Qian , Zhang Qichun , Qu Baihua 
Published: March 2023

AbstractThe metallic sodium (Na) is characterized by high theoretical specific capacity, low electrode potential and abundant resources, and its advantages manifests itself as a promising candidate anode of sodium metal batteries (SMBs). However, the vaporization during the plating/stripping or uncontrolled growth of sodium dendrites in sodium metal anodes (SMAs) has posed major challenges to its practical applications. To address this issue, here, the SnO2/Ti3C2Tx composite is rationally fabricated, in which sodiophilic SnO2 nanoparticles are in situ dispersed on the 2D Ti3C2Tx, providing the acceptor sites of Na+ that can control vaporization and dendrites. The SnO2/Ti3C2Tx composite anode exhibits smooth and homogeneous morphology after Na‐metal deposition cycles, stable Coulombic efficiency (CE) of half cells, long stable cycles of symmetric cells due to highly sodiophilic sites, and confinement effect. In addition, the full cells assembled with Na0.6MnO2 also show excellent rate performance and cycling performance. These discoveries demonstrate the effectiveness of the acceptor sites and the confinement effect provided by the SnO2/Ti3C2Tx composite, and thus provide an additional degree of freedom for designing SMBs.
Association of diet quality indices with serum and metabolic biomarkers in participants of the ORISCAV-LUX-2 study
Authors: Vahid Farhad , Hoge Axelle , Hébert James R. , Bohn Torsten ,   On behalf of the ORISCAV working group*., Alkerwi Ala’a , Noppe Stephanie , Delagardelle Charles , Beissel Jean , Chioti Anna , Stranges Saverio , Schmit Jean-Claude , Lair Marie-Lise , D’Incau Marylène , Pastore Jessica , Aguayo Gloria , Le Coroller Gwenaëlle , Vaillant Michel , Samouda Hanen , Appenzeller Brice , Malisoux Laurent , Couffignal Sophie , Gantenbein Manon , Devaux Yvan , Huiart Laetitia , Bejko Dritan , Fagherazzi Guy , Perquin Magali , Ruiz-Castell Maria , Ernens Isabelle 
Published: March 2023

Abstract
Purpose
Diet quality is a critical modifiable factor related to health, including the risk of cardiometabolic complications. Rather than assessing the intake of individual food items, it is more meaningful to examine overall dietary patterns. This study investigated the adherence to common dietary indices and their association with serum/metabolic parameters of disease risk.

Methods
Dietary intakes of the general adult population (n = 1404, 25–79 years) were assessed by a validated food-frequency questionnaire (174 items). The French ANSES-Ciqual food composition database was used to compute nutrient intakes. Seven indicators were calculated to investigate participants’ diet quality: the Alternative Healthy Eating Index (AHEI), Dietary Approaches to Stop Hypertension Score (DASH-S), Mediterranean Diet Score (MDS), Diet Quality Index-International (DQI-I), Dietary Inflammatory Index (DII), Dietary Antioxidant Index (DAI), and Naturally Nutrient-Rich Score (NNRS). Various serum/metabolic parameters were used in the validity and association analyses, including markers of inflammation, blood glucose, and blood lipid status.

Results
Following linear regression models adjusted for confounders, the DASH-S was significantly associated with most metabolic parameters (14, e.g., inversely with blood pressure, triglycerides, urinary sodium, uric acid, and positively with serum vitamin D), followed by the DQI-I (13, e.g., total cholesterol, apo-A/B, uric acid, and blood pressure) and the AHEI (11, e.g., apo-A, uric acid, serum vitamin D, diastolic blood pressure and vascular age).

Conclusion
Food-group-based indices, including DASH-S, DQI-I, and AHEI, were good predictors for serum/metabolic parameters, while nutrient-based indices, such as the DAI or NNRS, were less related to biological markers and, thus, less suitable to reflect diet quality in a general population.
Physiological Role of Arbuscular Mycorrhizae and Vitamin B1 on Productivity and Physio-Biochemical Traits of White Lupine (Lupinus termis L.) Under Salt Stress
Authors: Sadak Mervat Shamoon 
Published: March 2023

AbstractArbuscular mycorrhizalfungi (AMF) have a key role in natural and agricultural ecosystems affecting plant nutrition, soil biological activity and modifying the availability of nutrients. Thiamine (Vitamin B1) is an essential coenzyme which incorporated in a wide range of plant metabolic processes. Thus, this research aimed to study the possibility of mitigating the negative effect of salinity stress on white lupine plant via using AMF and Vit B1through assessment growth, various physiological traits and yield components of the white lupine plant. AMF was added to the soil (0.0 and 7 g pot−1) and Vit B1was foliar applied to white lupine seedlings (0.0, 100 and 200 mgL−1) and watered by two levels of salinity (0.0 or 5000 mgL−1). Salinity stress (5000 mgL−1) resulted in significant reductions in growth photosynthetic pigments constituents, endogenous indole acetic acid (IAA), some elements & productivity of white lupine in comparison to control plants. While, increasing phenols, some osmolytes and sodium compared to control (plants irrigated by tap water). Adding AMF to soil with the recommended dose boosted white lupine growth, certain physiological aspects and productivity in white lupine plants under irrigation with saltwater (5000 mgL−1). Furthermore, exogenous Vit B1 treatment with 100 & 200 mgL−1not only enhanced growth and seeds productivity of white lupine plants under normal irrigation but also, improved salinity tolerance by increasing white lupine growth and productivity via inmproving photosynthetic pigments, osmolytes levels and element contents compared to their corresponding controls. Finally it could be concluded that, 200 mgL−1Vit B1 wit AMF treatment shows superiority in inducing maximum improving white lupine plant salinity tolerance.