bluuebunny/crossref_metadata_2025_split huggingface dataset:
Family involvement and school effectiveness in primary education
Authors: Aierbe-Barandiaran Ana , Bartau-Rojas Isabel , Oregui-González Eider 
Published: January 2023

The commonly accepted premise that collaboration among the educational community leads to school improvement and greater student achievement is not always fulfilled due to the diverse reality of schools and various initiatives to promote family participation. This work addresses the perception of teachers, school management teams and educational inspection of family-school-community relations in 23 primary schools in the Basque Autonomous Community, characterized by different criteria related to school effectiveness-ineffectiveness, aiming to identify good practice leading to school improvement. The study is descriptive-exploratory-exploratory-explanatory with mixed methodology, using questionnaires, in-depth interviews and discussion groups. Results show family involvement is mediated by teaching staff´s personal factors, that all schools try to promote family collaboration, though forms of participation vary, and those which work best are proactive, stressing different collaboration dimensions. Conclusions include adopting a systemic approach, review and updating of training modalities, and assessment of teaching competences for collaboration.
La premisa ampliamente aceptada de que el trabajo colaborativo entre los diferentes agentes de la comunidad educativa redunda en la mejora escolar y en mayores logros alcanzados por el alumnado no siempre se cumple debido a la realidad diversa que presentan los centros y a las diferentes iniciativas para impulsar la participación familiar. El estudio aborda la percepción que docentes, equipos directivos e inspección educativa tienen de las relaciones familia-escuela-comunidad en 23 centros de primaria de la Comunidad Autónoma Vasca, caracterizados por diferentes criterios de eficacia-ineficacia escolar, con la finalidad de identificar buenas prácticas que contribuyan a la mejora escolar. Se trata de un estudio descriptivo-exploratorio-explicativo de metodología mixta, con empleo de cuestionarios, entrevistas en profundidad y grupos de discusión. Los resultados muestran que la implicación familiar está mediatizada por factores personales del profesorado, que todos los centros tratan de impulsar la colaboración familiar, aunque las formas y acciones de participación varían, y que aquellos que mejor funcionan tienen una actitud proactiva, con énfasis en dimensiones diferentes de colaboración. Entre las conclusiones cabe destacar la adopción de un enfoque sistémico, la revisión y actualización de las modalidades formativas, y la evaluación de las competencias docentes para la colaboración.
Internal Structure and Invariance of a Brief Version of the Marijuana Motives Measure (MMM-P15) in a Peruvian Population of Marijuana users
Authors: Vallejos-Flores Miguel , Capa-Luque Walter , Caycho-Caja Aaron , Chavez Santamaria Alexandra , Reyes-Baca Gino , Bello-Vidal Catalina 
Published: January 2023

Background: The identification of the reasons for marijuana use has been supported by instruments such as the MMM. Despite its importance, there are still no valid brief versions of this instrument in Latin American countries. This paper seeks to fill this gap by providing evidence of validity and reliability, as well as the structural invariance of the MMM. Method: The sample consisted of 1164 male and female marijuana users, aged between 18 and 49 years, from Lima and Callao. Results: The factor analysis found a pentafactorial structure. The brief version (MMM-P15) and the wide MMM showed favorable properties from structure and reliability (ꙍ > 0.88, H > .84) with a slight superiority of the short instrument (RMSEA = .058 [CI 90% .050, .067], SRMR = 0.044, TLI = 0.99, CFI = 0.99). Likewise, both versions maintain the invariance of the instrument according to sex and evidence of internal validity was found (AVE > 0.50). Conclusions: The MMM-P15 shows psychometric properties that support its use in both male and female marijuana users, and it is a short, versatile, and useful instrument for research purposes even in clinical settings.
Antecedentes: La identificación de los motivos por los cuales se consume marihuana se ha visto apoyada por instrumentos como el MMM. A pesar de su importancia, aún no se cuenta con versiones breves válidas de este en países latinoamericanos. Este trabajo busca cubrir esta carencia aportando evidencia de validez y confiabilidad, así como la invarianza estructural del MMM. Método: La muestra comprende 1164 consumidores de marihuana, varones y mujeres, con edades entre 18 y 49 años, de Lima y Callao. Resultados: El análisis factorial halló una estructura pentafactorial. La versión breve (MMM-P15) y extensa (MMM) muestran favorables propiedades de estructura y consistencia interna (ꙍ > 0.88, H > .84) con una ligera superioridad del instrumento corto (RMSEA = .058 [IC 90% .050, .067], SRMR = .044, GFI = .99, TLI = .99, CFI = .99). Asimismo, ambas versiones mantienen la invarianza según el sexo y se encontró evidencia de validez interna (AVE > 0.50). Conclusiones: El MMM-P15 evidencia propiedades psicométricas que respaldan su uso tanto en hombres y mujeres consumidores de marihuana, además es un instrumento corto, versátil y útil para fines de investigación incluso en contextos clínicos.
Evaluación del efecto de la indagación guiada sobre la competencia científica en estudiantes de Educación Secundaria
Authors: Albertos Gómez Daniel 
Published: January 2023

Esta investigación tiene dos objetivos: aportar evidencia acerca de la eficacia de la metodología Inquiry Based Science Education (IBSE) para desarrollar la competencia científica de estudiantes de 12-13 años y establecer una manera fiable de evaluar dicho proceso de aprendizaje mediante un test diseñado ad-hoc. Se empleó un diseño cuasi-experimental, con tres grupos que realizaron un test con medidas antes y después del tratamiento. Dicho test obtuvo un valor de fiabilidad de 0,75 en el estadístico alfa de Cronbach. El análisis de la varianza realizado mostró que el grupo que recibió el tratamiento mejoró su rendimiento en competencia científica de manera significativa con respecto a los grupos que siguieron un tratamiento de enseñanza expositiva. Igualmente, se observó que el tamaño del efecto fue muy alto (d = 1,2). El test se ha comportado como una herramienta útil en la evaluación cuantitativa de habilidades científicas en estudiantes de 1º de ESO.
A systematic analysis of anti-diabetic medicinal plants from cells to clinical trials
Authors: Omale Simeon , Amagon Kennedy I. , Johnson Titilayo O. , Bremner Shaun Kennedy , Gould Gwyn W. 
Published: January 2023

Background
Diabetes is one of the fastest-growing health emergencies of the 21st century, placing a severe economic burden on many countries. Current management approaches have improved diabetic care, but several limitations still exist, such as decreased efficacy, adverse effects, and the high cost of treatment, particularly for developing nations. There is, therefore, a need for more cost-effective therapies for diabetes management. The evidence-based application of phytochemicals from plants in the management of diseases is gaining traction.

Methodology
Various plants and plant parts have been investigated as antidiabetic agents. This review sought to collate and discuss published data on the cellular and molecular effects of medicinal plants and phytochemicals on insulin signaling pathways to better understand the current trend in using plant products in the management of diabetes. Furthermore, we explored available information on medicinal plants that consistently produced hypoglycemic effects from isolated cells to animal studies and clinical trials.

Results
There is substantial literature describing the effects of a range of plant extracts on insulin action and insulin signaling, revealing a depth in knowledge of molecular detail. Our exploration also reveals effective antidiabetic actions in animal studies, and clear translational potential evidenced by clinical trials.

Conclusion
We suggest that this area of research should be further exploited in the search for novel therapeutics for diabetes.
Genetically Modified Crop vs Hybrid Crops and their Impact on Health and Environment
Authors: Mahmuda Raisa , Mondal Satyen , Rahman Abiar , Ahmed Minhaz , Parvin Shohana , Ahmed Tofayel 
Published: January 2023

Genetically modified crop (GMC) is a technology which includes transferring Deoxyribonucleic acid (DNA) in plant cells. On the other hand, Hybrid Crops are naturally occurring crops but it also involves manmade crosses to have at least 15-20% higher yield potential over high yielding inbred crop varieties using almost the same level of inputs and also can perform better even under unfavourable environments like drought and saline condition. These days, hybrid crops are one of the most commonly consumed foods for humans. In line with this GM crops have high yield potential and adaptive capability under wide range of environments even under fragile ecosystems. There are different aspects of both these types of crops. Human consumption of these crops has been a highly debatable topic in recent times. In this study, a brief discussion on GM crops and hybrid crops will be presented. Additionally, a comparison between them, in terms of health and productivity, will also be discussed.
Association of Appropriate Empirical Antimicrobial Therapy With In-Hospital Mortality in Patients With Bloodstream Infections in the US
Authors: Ohnuma Tetsu , Chihara Shingo , Costin Blair , Treggiari Miriam M. , Bartz Raquel R. , Raghunathan Karthik , Krishnamoorthy Vijay 
Published: January 2023

ImportanceBloodstream infections (BSIs) are a major public health problem associated with high morbidity. Little evidence exists regarding the epidemiology of BSIs and the use of appropriate empirical antimicrobial therapy.ObjectiveTo estimate the association between receipt of appropriate initial empirical antimicrobial therapy and in-hospital mortality.Design, Setting, and ParticipantsThis retrospective cross-sectional study used data from the Premier Healthcare database from 2016 to 2020. The analysis included 32 100 adult patients (aged ≥18 years) with BSIs from 183 US hospitals who received at least 1 new systemic antimicrobial agent within 2 days after blood samples were collected during the hospitalization. Patients with polymicrobial infections were excluded from the analysis.ExposuresAppropriate empirical therapy was defined as initiation of at least 1 new empirical antimicrobial agent to which the pathogen isolated from blood culture was susceptible either on the day of or the day after the blood sample was collected.Main Outcomes and MeasuresMultilevel logistic regression models were used to estimate the association between receipt of appropriate initial empirical antimicrobial therapy and in-hospital mortality for patients infected with gram-negative rods (GNRs), gram-positive cocci (GPC), and Candida species.ResultsAmong 32 100 patients who had BSIs and received new empirical antimicrobial agents, the mean (SD) age was 64 (16) years; 54.8% were male, 69.9% were non-Hispanic White, and in-hospital mortality was 14.3%. The most common pathogens were Escherichia coli (58.4%) and Staphylococcus aureus (31.8%). Among patients infected with S aureus, methicillin-resistant S aureus was isolated in 43.6%. The crude proportions of appropriate empirical therapy use were 94.4% for GNR, 97.0% for GPC, and 65.1% for Candida species. The proportions of appropriate therapy use for resistant organisms were 55.3% for carbapenem-resistant Enterobacterales species and 60.4% for vancomycin-resistant Enterococcus species. Compared with inappropriate empirical therapy, receipt of appropriate empirical antimicrobial therapy was associated with lower in-hospital risk of death for 3 pathogen groups (GNR: adjusted odds ratio [aOR], 0.52 [95% CI, 0.42-0.64]; GPC: aOR, 0.60 [95% CI, 0.47-0.78]; Candida species: aOR, 0.43 [95% CI, 0.21-0.87]).Conclusions and RelevanceIn this cross-sectional study of patients hospitalized with BSIs, receipt of appropriate initial empirical antimicrobial therapy was associated with lower in-hospital mortality. It is important for clinicians to carefully choose empirical antimicrobial agents to improve outcomes in patients with BSIs.
Linac primary barrier transmission: Flattening filter free and field size dependence
Authors: McDermott Patrick N. , Drake Douglas , Knill Cory , Sigler Michael D. 
Published: January 2023

AbstractThere is widespread consensus in the literature that flattening filter free (FFF) beams have a lower primary barrier transmission than flattened beams. Measurements presented here, however, show that for energy compensated FFF beams, the barrier transmission can be as much as 70% higher than for flattened beams. The ratio of the FFF barrier transmission to the flattened beam barrier transmission increases with increasing barrier thickness. The use of published FFF TVL data for energy compensated FFF beams could lead to an order of magnitude underestimate of the air kerma rate. There are little data in the literature on the field size dependence of the barrier transmission for flattened beams. Barrier transmission depends on the field size at the barrier, not at isocenter Measurements are presented showing the relative dependence of barrier transmission on the field size, measured at the barrier, for 6 MV and 10 MV beams. An analytical fitting formula is provided for the field size dependence. For field sizes greater than about 150 cm in side length, the field size dependence is minimal. For field sizes less than about 100 cm, the transmission declines rapidly as the field size decreases.
“Cluster Bomb” Based Bismuth Nano‐in‐Micro Spheres Formed Dry Powder Inhalation for Thermo‐Radio Sensitization Effects of Lung Metastatic Breast Cancer
Authors: Wang Qiyue , Liu Ji , Chen Daquan , Miao Si , Wen Jing , Liu Chang , Xue Shushu , Liu Yang , Zhang Qingjie , Shen Yan 
Published: January 2023

AbstractLung metastatic breast cancer (LMBC) is mainly diagnosed through CT imaging and radiotherapy could be the most common method in the clinic to inhibit tumor proliferation. While the sensitivity of radiotherapy is always limited due to the hypoxic tumor microenvironment and high doses of irradiation easily induce systemic cytotoxicity. Metal‐based materials applied as radiosensitizers have been widely investigated to improve efficiency and reduce the doses of irradiation. Herein, it is aimed to overcome these problems by designing biodegradable lipid‐camouflaged bismuth‐based nanoflowers (DP‐BNFs) as both a photo‐thermo‐radiosensitizer to develop a novel photothermal therapy (PTT) and radiotherapy combination strategy for LMBC treatment. To achieve effective lung deposition, “Cluster Bomb” structure‐based DP‐BNFs nano‐in‐micro dry powder inhalation (DP‐BNF@Lat‐MPs) are formulated through spray‐dried technology. The DP‐BNFs “cluster” in the microsphere to improve their tumor‐targeted lung deposition with a high fine particle fraction followed by burst releasing of DP‐BNFs for targeting delivery and LMBC therapy. The DP‐BNF@Lat‐MPs exhibit excellent photothermal conversion efficiency, radiotherapy enhancement, and CT imaging ability in vitro, which synergistically inhibit cell proliferation and metastasis. In vitro and in vivo data prove that combining PTT and radiotherapy with DP‐BNF@Lat‐MPs as a thermo‐radio dual‐sensitizer significantly enhances LMBC tumor metastasis inhibition with good biocompatibility and low toxicity.
Nanocomposite Engineering of a High‐Capacity Partially Ordered Cathode for Li‐Ion Batteries
Authors: Lee Eunryeol , Wi Tae‐Ung , Park Jaehyun , Park Sang‐Wook , Kim Min‐Ho , Lee Dae‐Hyung , Park Byung‐Chun , Jo Chiho , Malik Rahul , Lee Jong Hoon , Shin Tae Joo , Kang Seok Ju , Lee Hyun‐Wook , Lee Jinhyuk , Seo Dong‐Hwa 
Published: January 2023

AbstractUnderstanding the local cation order in the crystal structure and its correlation with electrochemical performances has advanced the development of high‐energy Mn‐rich cathode materials for Li‐ion batteries, notably Li‐ and Mn‐rich layered cathodes (LMR, e.g., Li1.2Ni0.13Mn0.54Co0.13O2) that are considered as nanocomposite layered materials with C2/m Li2MnO3‐type medium‐range order (MRO). Moreover, the Li‐transport rate in high‐capacity Mn‐based disordered rock‐salt (DRX) cathodes (e.g., Li1.2Mn0.4Ti0.4O2) is found to be influenced by the short‐range order of cations, underlining the importance of engineering the local cation order in designing high‐energy materials. Herein, the nanocomposite is revealed, with a heterogeneous nature (like MRO found in LMR) of ultrahigh‐capacity partially ordered cathodes (e.g., Li1.68Mn1.6O3.7F0.3) made of distinct domains of spinel‐, DRX‐ and layered‐like phases, contrary to conventional single‐phase DRX cathodes. This multi‐scale understanding of ordering informs engineering the nanocomposite material via Ti doping, altering the intra‐particle characteristics to increase the content of the rock‐salt phase and heterogeneity within a particle. This strategy markedly improves the reversibility of both Mn‐ and O‐redox processes to enhance the cycling stability of the partially ordered DRX cathodes (nearly ≈30% improvement of capacity retention). This work sheds light on the importance of nanocomposite engineering to develop ultrahigh‐performance, low‐cost Li‐ion cathode materials.
Giant Increase of Hardness in Silicon Carbide by Metastable Single Layer Diamond‐Like Coating
Authors: Rejhon Martin , Zhou Xinliu , Lavini Francesco , Zanut Alessandra , Popovich Filip , Schellack Lorenzo , Witek Lukasz , Coelho Paulo , Kunc Jan , Riedo Elisa 
Published: January 2023

AbstractSilicon carbide (SiC) is one of the hardest known materials. Its exceptional mechanical properties combined with its high thermal conductivity make it a very attractive material for a variety of technological applications. Recently, it is discovered that two‐layer epitaxial graphene films on SiC can undergo a pressure activated phase transition into a sp3 diamene structure at room temperature. Here, it is shown that epitaxial graphene films grown on SiC can increase the hardness of SiC up to 100% at low loads (up to 900 µN), and up to 30% at high loads (10 mN). By using a Berkovich diamond indenter and nanoindentation experiments, it is demonstrated that the 30% increase in hardness is present even for indentations depths of 175 nm, almost three hundred times larger than the graphene film thickness. The experiments also show that the yield point of SiC increases up to 77% when the SiC surface is coated with epitaxial graphene. These improved mechanical properties are explained with the formation of diamene under the indenter's pressure.
Mature Red Blood Cells Contain Long DNA Fragments and Could Acquire DNA from Lung Cancer Tissue
Authors: Liang Naixin , Jiao Zichen , Zhang Cong , Wu Yifan , Wang Tao , Li Shanqing , Wang Yadong , Song Tianqiang , Chen Jian‐Qun , Liang Hongwei , Chen Qihan 
Published: January 2023

AbstractRed blood cells (RBC) are commonly known as cells with no nucleus or mitochondria and are assumed to be a transportation vehicle. This study confirms that RBC contain long DNA fragments inside with stain by both microscope and flow cytometry, which covers most nuclear and mitochondrial genome regions by next‐generation sequencing (NGS). Such characteristics demonstrate a significant difference compared with A549 cell line or paired peripheral blood mononuclear cell as nucleated cells. To further explore the characteristics of RNA DNA, DNA from 20 RBC samples is sequenced by NGS. Interestingly, several gaps and multiple regions with copy number variation are observed significantly different between different samples, which could be used to distinguish samples with different health status accurately. Using an in vitro co‐culture system, it is shown that RBC could absorb DNA‐bearing tumorigenic mutations from cancer cell lines but requires cell‐to‐cell contact. Finally, based on a small scale clinical trial, it is confirmed that common genetic mutations of cancer tissues could be detected in RBC from patients with early‐stage non‐small‐cell lung cancer. This study highlights a new biological phenomenon involving RBC and its translational potential as a novel liquid biopsy technology platform for early cancer screening and diagnosis of malignancy.
Efficient Ohmic Contact in Monolayer CrX2N4 (X = C, Si) Based Field‐Effect Transistors
Authors: Shu Yu , Liu Yongqian , Cui Zhou , Xiong Rui , Zhang Yinggan , Xu Chao , Zheng Jingying , Wen Cuilian , Wu Bo , Sa Baisheng 
Published: January 2023

AbstractDeveloping Ohmic contact systems or achieving low contact resistance is significant for high‐performance semiconductor devices. This work comprehensively investigates the interfacial properties of CrX2N4 (X = C, Si) based field‐effect transistors (FETs) with different metal (Ag, Au, Cu, Ni, Pd, Pt, Ti, and graphene) electrodes by using electronic structure calculations and quantum transport simulations. It is highlighted that the stronger interlayer coupling allows CrC2N4 to form an n‐type Ohmic contact with Ti electrode in the vertical direction. Furthermore, the absence of tunneling barrier at the CrC2N4–Ti interface greatly improves the electron injection efficiency. On the other hand, the studied metals form Schottky contact with CrC2N4 at the lateral interface due to Fermi level pinning (FLP) effects. Surprisingly, the strong FLP effects restrict the Schottky barrier heights of CrSi2N4‐metal contacts to a narrow range. Where Ag, Au, Ni, Pd, Pt, Ti electrodes and Ag, Ti electrodes form ideal ohmic contact with CrSi2N4 in the vertical and lateral directions, respectively, while the other metals form quasi‐ohmic contact. Ti exhibits the highest contact performance as the electrode in both CrC2N4 and CrSi2N4 based FETs. The findings may provide fundamental understanding for designing high‐performance and energy‐efficient FETs based on CrX2N4.
Biodegradable and Bioabsorbable Polylactic Acid Ferroelectrets with Prominent Piezoelectric Activity
Authors: Ma Xingchen , Zhukov Sergey , von Seggern Heinz , Sessler Gerhard M. , Ben Dali Omar , Kupnik Mario , Dai Ying , He Pengfei , Zhang Xiaoqing 
Published: January 2023

AbstractFerroelectrets have promoted a variety of exciting flexible sensors, actuators, and microenergy harvesters. However, most ferroelectrets have been fabricated from non‐degradable petro‐based resins, and thus the recycling of these materials constitutes a big challenge. This article reports biodegradable and bioabsorbable ferroelectret films made from polylactic acid (PLA) resins for highly sensitive transducer applications, which can operate either in piezoelectric 33 or 31/32 mode. By modification of the microstructure and polarization, pronounced longitudinal and transverse piezoelectric activities are realized in a single material. For samples with a thickness of 400 µm and a bulk density of 350 kg m−3, the Young's moduli in thickness and plane direction are ranging from 0.1 to 10 MPa, respectively. After polarization in the thickness direction, quasi‐static piezoelectricd33,g33,d31(d32), andg31(g32) coefficients in the PLA films, up to 500 pC N−1, 40 Vm N−1, −44 pC N−1, and −3.6 Vm N−1, are achieved, respectively. The longitudinal piezoelectric coefficients of the PLA films are comparable to non‐degradable polymer ferroelectrets, while the transverse piezoelectric activity is superior, which may be attributed to the reduction of Young's moduli in the plane direction. The preparation procedure of the PLA ferroelectrets is compatible with large‐scale production lines and thus can greatly promote their applications in green electronics.