bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dipalmitoyl-phosphatidylserine-filled cationic maltodextrin nanoparticles exhibit enhanced efficacy for cell entry and intracellular protein delivery in phagocytic THP-1 cells
Authors: Brinkhuizen Clément , Shapman Damien , Lebon Alexis , Bénard Magalie , Tardivel Meryem , Dubuquoy Laurent , Galas Ludovic , Carpentier Rodolphe 
Published: June 2023

Abstract
Vaccination through the upper respiratory tract is a promising strategy, and particulate antigens, such as antigens associated with nanoparticles, triggered a stronger immune response than the sole antigens. Cationic maltodextrin-based nanoparticles loaded with phosphatidylglycerol (NPPG) are efficient for intranasal vaccination but non-specific to trigger immune cells. Here we focused on phosphatidylserine (PS) receptors, specifically expressed by immune cells including macrophages, to improve nanoparticle targeting through an efferocytosis-like mechanism. Consequently, the lipids associated with NPPG have been substituted by PS to generate cationic maltodextrin-based nanoparticles with dipalmitoyl-phosphatidylserine (NPPS). Both NPPS and NPPG exhibited similar physical characteristics and intracellular distribution in THP-1 macrophages. NPPS cell entry was faster and higher (two times more) than NPPG. Surprisingly, competition of PS receptors with phospho-L-serine did not alter NPPS cell entry and annexin V did not preferentially interact with NPPS. Although the protein association is similar, NPPS delivered more proteins than NPPG in cells. On the contrary, the proportion of mobile nanoparticles (50%), the movement speed of nanoparticles (3 µm/5 min), and protein degradation kinetics in THP-1 were not affected by lipid substitution. Together, the results indicate that NPPS enter cells and deliver protein better than NPPG, suggesting that modification of the lipids of cationic maltodextrin-based nanoparticles may be a useful strategy to enhance nanoparticle efficacy for mucosal vaccination.
Gelfand–Kirillov dimension and the p-adic Jacquet–Langlands correspondence
Authors: Dospinescu Gabriel , Paškūnas Vytautas , Schraen Benjamin 
Published: June 2023

Abstract
We bound the Gelfand–Kirillov dimension of unitary Banach space
representations of p-adic reductive groups, whose locally analytic vectors afford
an infinitesimal character. We use the bound to study Hecke eigenspaces in completed
cohomology of Shimura curves and p-adic Banach space representations of the group of units of a quaternion algebra over

ℚ
p

{\mathbb{Q}_{p}}

appearing in the
p-adic Jacquet–Langlands correspondence, deducing finiteness results in favorable cases.
A compartmental model of the COVID-19 pandemic course in Germany
Authors: Adalıoğlu Yıldırım , Kaplan Çağan 
Published: June 2023

Abstract

Objectives
In late 2019, the novel coronavirus, known as COVID-19, emerged in Wuhan, China, and rapidly spread worldwide, including in Germany. To mitigate the pandemic’s impact, various strategies, including vaccination and non-pharmaceutical interventions, have been implemented. However, the emergence of new, highly infectious SARS-CoV-2 strains has become the primary driving force behind the disease’s spread. Mathematical models, such as deterministic compartmental models, are essential for estimating contagion rates in different scenarios and predicting the pandemic’s behavior.

Methods
In this study, we present a novel model that incorporates vaccination dynamics, the three most prevalent virus strains (wild-type, alpha, and delta), infected individuals’ detection status, and pre-symptomatic transmission to represent the pandemic’s course in Germany from March 2, 2020, to August 17, 2021.

Results
By analyzing the behavior of the German population over 534 days and 25 time intervals, we estimated various parameters, including transmission, recovery, mortality, and detection. Furthermore, we conducted an alternative analysis of vaccination scenarios under the same interval conditions, emphasizing the importance of vaccination administration and awareness.

Conclusions
Our 534-day analysis provides policymakers with a range of circumstances and parameters that can be used to simulate future scenarios. The proposed model can also be used to make predictions and inform policy decisions related to pandemic control in Germany and beyond.
Performance of a horizontal well in a bounded anisotropic reservoir: Part II: Performance analysis of well length and reservoir geometry
Authors: Nzomo Timothy Kitungu , Adewole Stephen Ezizanami , Awuor Kennedy Otieno , Okang’a Oyoo Daniel 
Published: June 2023

Abstract
Evaluation of the performance of horizontal wells is an important aspect in the enhancement of their productivity. This study provides mathematical computations, and analysis for theoretical well and reservoir considerations. The study investigates how well design and reservoirs geometry affect the overall performance of a horizontal well in a completely bounded reservoir throughout its productive life. A horizontal well in a rectangular reservoir with completely sealed boundaries is considered and the effect of dimensionless well length

L

D

\hspace{.25em}{L}_{\text{D}}

, dimensionless reservoir length

x

eD

\hspace{.25em}{x}_{\text{eD}}

, and dimensionless reservoir width

y

eD

{y}_{\text{eD}}

on the pressure response over a given period of production using dimensionless time

t

D

{t}_{\text{D}}

is studied. The mathematical model used was derived using source and Green’s functions presented in part I of this study. Appropriate well and reservoir parameters are considered and the respective dimensionless parameters are computed which are then used in computing dimensionless pressure

P

D

{P}_{\text{D}}

and its dimensionless pressure derivative

P

D

′

\hspace{.25em}{P}_{\text{D}}^{^{\prime} }

. From the computations, the results obtained are analysed in diagnostic log–log plots with a discussion of the flow periods. The results obtained indicate that an increase in dimensionless well length decreases pressure response during the infinite-acting flow at early times and during transition flows at middle time but increases the pressure response during the pseudosteady state flow at late times. The dimensionless reservoir width and length are observed not to influence dimensionless pressure response during the infinite-acting flow at early times and during the transition flows at middle time, only affecting the prevalence time of the flow periods. However it is observed that during the pseudosteady state flow at late times, dimensionless pressure response reduces with increased dimensionless reservoir length and width.
A profinite approach to complete bifix decodings of recurrent languages
Authors: Costa Alfredo 
Published: June 2023

Abstract
We approach the study of complete bifix decodings of (uniformly) recurrent languages with
the help of free profinite monoids. We show that the complete bifix decoding of a uniformly recurrent language F
by an F-charged rational complete bifix code is uniformly recurrent. An analogous result is obtained for recurrent languages.
As an application of the machinery developed within this approach, we show that the maximal pronilpotent quotient of the Schützenberger group of an irreducible symbolic dynamical system is an invariant of eventual conjugacy.
Millimeter wave over fiber based 50G-wavelength division multiplexed passive optical network for 5G and beyond communications
Authors: Singh Simranjit , Kaur Jagroop , Kaur Harpreet 
Published: June 2023

Abstract
In this paper, the 50 Gbps-passive optical network (50G-PON) is proposed by utilizing the millimeter wave over fiber concept. At the first stage, DP-MZM modulation schematic approach is used to modulate the millimeter wave at the distinct wavelengths. At Stage 2, a third MZM modulator is used by utilizing the WDM interleaver de-multiplexer. The bi-directional fiber is used to make the system symmetric which is a requirement of 50G-PON. The eye diagrams, quality factor and bit error rate are measured to analyze the performance of the proposed system for the different encoding formats i.e. non-returns to zero (NRZ), returns to zero (RZ) and Gaussian pulse. The proposed schematic approach is used to generate the millimeter wave in 3-tupling by using the select switch selection. The proposed millimeter based 50G-PON can support 5G and 6G for fronthauling.
Composite disc optimization using hunger games search optimization algorithm
Authors: Kopar Mehmet , Yildiz Ali Rıza 
Published: June 2023

Abstract
It has been interesting in industrial applications due to the advantages provided by laminated composite applications. Composite materials are of great importance in design optimization due to the advantages they provide, such as lightweight, high strength value, and design flexibility. Finite element programs and artificial intelligence optimization techniques developed in recent years are effectively used in the design of composite materials. In order to optimize the angular orientations of the composite disc, analyses are made using the finite element program. Particle swarm optimization algorithm (PSO), genetic algorithm (GA), and hunger games search optimization algorithm(HGS) are used to determine the best stacking angle value on the disc plate using the analysis data obtained after the completion of the analyses. When the results obtained were examined, it was determined that the results obtained from particle swarm optimization, genetic algorithm, and hunger games search optimization techniques showed that hunger games search optimization algorithm gives better results as other and HGS could be used for the stacking of composite materials.
Thienylpicolinamidine derivatives as new dissolution inhibitors for carbon steels in HCl medium: experimental and theoretical studies
Authors: Sakr Shrouk F. , Badr Gamila E. , Ismail Mohamed A. , Fouda Abd El-Aziz S. 
Published: June 2023

Abstract
One of the main ways that metallic materials lose their useful qualities is through dissolution; hence corrosion management is crucial for protecting the metal. In this paper, new thienylpicolinamidine derivatives, namely; 5-[5-(3,4,5-trimethoxyphenyl)thiophen-2-yl]picolinamidine hydrochloride salt (MA-1517), 5-[5-(4-methoxyphenyl)thiophen-2-yl]picolinamidine hydrochloride salt (MA-1543), and 5-[5-(3-chloro-4-methoxyphenyl)thiophen-2-yl]picolinamidine hydrochloride salt (MA-1516), were utilized as corrosion inhibitors for C-steel in 1.0 mol L−1 HCl. Their corrosion inhibiting impact can be demonstrated by experimental methods as chemical approaches (mass reduction) and electrochemical techniques (electrochemical impedance examination, EIS, and Tafel polarization). These methods gave inhibition efficiencies (IE%) of 97.41 %, 93.84 % and 91 % for MA-1517, MA-1543 and MA-1516, respectively at 323 K and concentration 17 × 10−6 mol. L−1. The rise in IE% with rising inhibitor concentration and temperature illustrate that the adsorption of these studied compounds is chemisorption, declared via the Langmuir isotherm. Thermodynamic and kinetic parameters are computed and discussed. Polarization research exhibits that these thienylpicolinamidines act as mixed type inhibitors. The outer part morphology of C-steel surfaces and the adsorption of these compounds on C-steel outer part can be checked by atomic force microscopy (AFM), scanning electron microscopy (SEM), and energy dispersive X-ray (EDX). The mechanism of inhibition can be backed by quantum chemical examination and Monte Carlo model. A theoretical estimate proves that the use of cationic derivatives of pyridine is good impediments versus corroding of C-steel in HCl medium.
III. Mediatio und superioritas
Authors: Kintzinger Martin 
Published: June 2023

Summary
From the 12th century onwards, arbitration tribunals came into use and until the 15th century they were established as alternative legal practice. While the Roman Law became institutionalized as an instrument of political power, the arbitration tribunals retained their value as elements of noble communication in case of crisis within European realms. In international politics and law, arbitration tribunals were often brought into play, but failed to be successful as instrument of international conflict management.
VII. Entspricht das jetzt dem Volksgeist? Geltungsfragen im „Heutigen Römischen Recht“
Authors: Haferkamp Hans-Peter 
Published: June 2023

Summary

Does this comply with the “Volksgeist” now? Questions of validity in “Modern Roman Law”. The article examines the impact of the “Volksgeist” (national spirit), as the basis of the theory of legal sources developed by the Historical School of Law, on methodological history. Although in 1814 Savigny used the term “sensing the principles”, the methodological history, even nowadays, assumes that the “Volksgeist” exclusively contains rational structures and is therefore ‘reasonable’. Still and despite all doubts concerning this concept, the “Volksgeist” is merged with “Begriffsjurisprudenz” (conceptual jurisprudence). In contrast, this article develops a methodological program of the Historical School of Law in which rational approaches were always accompanied by irrational ones, appealing to intuition, a sense of justice, and a ‘child-like sense’ as an access to truth. Viewed from a philosophical perspective, the decisive key terms, introduced by Savigny in 1814, are “nature, fate and need”. Methodologically, the focus reveals, around the special significance of “analogy”, the “nature of things”, the “practical needs” and the “sense of justice” as ways to contribute to the legal cognition.
Unter einem „neuen Himmel“? Wachstum und Wandel im juristischen Publikationswesen an der Wende zum 20. Jahrhundert
Authors: Kästle-Lamparter David 
Published: June 2023

Summary
Around 1900, legal literature and publishing in Germany underwent a significant process of expansion and transformation. This development is, in part, due to the codification of important areas of law, especially the advent of the German Civil Code. The new codes instigated a vast quantity of legal literature; legal commentaries took the lead in explaining the new law. However, it is only through a look at the history of books and publishing, as well as the general history of science, that the development of legal literature can be fully appreciated. This paper shows that the growth and transformation of legal literature before and after 1900 is part of a larger development, i.e. the emergence of a literary mass-market, on the one hand, and the formation of what Adolf von Harnack called a ‘large-scale industry of science’, on the other hand.
In the shadow of Auschwitz … Jews before Special Courts of the ‘Third Reich’ 1933–1945
Authors: Graczyk Konrad 
Published: June 2023

Summary
This article offers a qualitative and quantitative analysis of the presence of Jews before Special Courts of the ‘Third Reich’. The research shows that the participation of Jews as defendants before Special Courts in the so-called Old Reich was marginal. The situation was different in polish areas incorporated into the Reich. Attention is here paid to the numbers of defendants and other penalty statistics, to some types of imputed acts, and to attempts to use courts and court sentencing to take the lives of Jews.
Repository for Digital Editions of Legal Historical Sources: ‘IURA. Sources of Law from the Past’The research for this publication has been supported by a grant from the Priority Research Area Heritage under the Strategic Programme Excellence Initiative at Jagiellonian University, project “Edition of Polish Legal Writings 16th–18th cent. Preliminary (H.1.3.2021.67)”.)
Authors: Mikuła Maciej 
Published: June 2023

Summary
The article is a short presentation of the knowledge base ‘IURA. Sources of Law from the Past’ (https://iura.uj.edu.pl/dlibra). The main goal of the project is to build a comprehensive knowledge base with interlinked and easily searchable content from various sources of historical law. The system of content links will help the user to get a broader picture of various sections or dimensions of the legal world, i.e. texts of the law and normative regulations, references to the law or laws, legal literature, or references to the implementation of the law. A set of advanced search tools will enable the user to find and select, with some degree of precision, the scope of relevant content throughout the digitalized source material. Moreover, it will be possible to conduct searches using standardized metadata descriptions. The article contains a short description of selected sources collections.
IV. Ira Dei venit de coelo in filios diffidentiae. Zur Verbindung von Häresie und Sodomie aus kanonistischer Perspektive
Authors: Kulp Kevin 
Published: June 2023

Summary
This paper questions the narrative widely used in historical research that from the time after the Fourth Lateran Council (1215), the canonical punishment of sodomy was tightened and sodomy was ultimately persecuted as heresy. Particular attention is paid to the ecclesiastical prosecution of heresy in the pontificate of Gregory IX in comparison to the treatment of the offence at the Lateran Councils of 1179 and 1215 as well as in the confession summa of Raymund of Peñafort. Due to the opposing presentations of the issue by Raymund and Gregory, this essay also contributes to the question of the relationship between the Pope and the compiler of the Liber Extra.
VII. Vom objektiven Maßstab zum subjektiven Urteil
Authors: Schmoeckel Mathias 
Published: June 2023

Abstract

From an objective scale to a subjective verdict. The Role of the Judge in the work of Johann Oldendorp and the re-evaluation of the roman-canon law of evidence in Humanism and Protestant Reformation. The roman-canon law of procedure was based on the assumptions of the Church fathers that laws on jurisdiction would guarantee objective and just decisions. Humanism, however, relied on the assumption that education and knowledge would teach the individual; not general rules, but expertise would lead to cognition and justice. In order to save the traditional law of procedure, Johann Oldendorp, one of the most innovative Protestant lawyers, taught that the best educated judge with sufficient practical experience should still keep the promise of objective, just decisions. Although the ideas on hermeneutics had changed profoundly by then, this reasoning helped to find convincing verdicts in the procedure of the old roman-canon law.
Neue Erkenntnisse und Überlegungen zur Edition der Summa decretorum des Huguccio
Authors: Becker Niels , Rehak Martin 
Published: June 2023

Abstract

New insights and ideas for an edition of Huguccio’s Summa decretorum. A critical edition of Huguccio’s monumental and eminently influential Summa decretorum has long been an urgent desideratum of canonist research. The present contribution evaluates previous research conducted by Oldřich Přerovský (1924–2013) and presents the results of our own sample edition of parts of Huguccio’s commentary on the pars prima of the Decretum Gratiani. In particular, we offer new insights into the Summa’s complex manuscript tradition and propose a thorough revision of Přerovský’s editorial methodology with the aim of relaunching the Huguccio edition in the future.
Ordres et conflits de juridictions. L’appel comme d’abus: levier processuel, objet politique
Authors: Baud Charles 
Published: June 2023

Abstract

Orders and conflicts of jurisdictions. The procedure of appeal against an abuse of ecclesiastical power, processual lever, political object. The procedure of appeal as abuse was profoundly reformed by King François I, in the great ordinance signed at Villers-Cotterêts in August 1539. The concept underlying this reform set it up as a political lever in the fight against ecclesiastical jurisdictions, in a Gallican perspective. From the 16th to the 18th century, jurists thus turned a simple procedure into a real political tool in the service of their ideas.
En la estela azul del Oriente. El lapislázuli del Tesoro de Tod
Authors: Del Cerro Linares Carmen 
Published: June 2023

El Tesoro de Tod es uno de los hallazgos más llamativos del Próximo Oriente en relación al lapislázuli. Las piezas del Tesoro ya fueron catalogadas en los años treinta del S. XX, pero las que estaban realizadas en lapislázuli fueron mal estudiadas. El Tesoro de Tod supone una de las mayores acumulaciones de esta piedra fuera de Asia Central. La existencia de sellos dentro del tesoro nos permite considerar su cronología y la proveniencia de alguno de sus objetos, así como acercar diversas regiones del Próximo Oriente antiguo.Palabras clave: Tod, Montu, lapislázuli, plata, glíptica, intercambios comerciales, periodo Isin-Larsa, Dinastía XII.AbstractTod Treasure is one of the most amazing findings related to Lapis lazuli throughout the Ancient Near East. The different objects of this treasure were cataloged in the ‘30s of the twentieth century, but the Lapis lazuli items haven been poorly studied. Tod Treasure means one of the biggest hoard composed by this blue stone outside Central Asia. The existence of seals included in the Treasure let us to consider the Chronology and Provenance of some objects as well as to approach different areas from Ancient Near East.Keywords: Tod, Montu, Lapis lazuli, Silver, Glyptic, Trade Exchanges, Isin-Larsa period, XII Dynasty.
Policy Influencer dalam Kebijakan Luar Negeri Australia terhadap Pencari Suaka pada Masa Pemerintahan Julia Gillard
Authors: Azmi Agus Nilmada , H Febri Dirgantara 
Published: June 2023

Abstract. This study discusses the policy influencer of Australia's policy towards asylum seekers during the reign of Julia Gillard from 2010-2013. These approaches incorporate the re-implementation of the Pacific Solution, the return of asylum seekers to their countries of origin, and the Malaysia Solution, beside other policies. This study uses the theory of policy influence system and prejudice theory in explaining the policies implemented by the government of Australia in managing with asylum seeker amid the reign of Julia Gillard and the components behind the policy-making. The analytical ranking used is the nation-state. This research is qualitative research with descriptive type. The results of this study indicate that Australia's policy towards asylum seekers under the Gillard government is influenced by three policy influencing factors, namely the bureaucracy, parties, and the public, which are full of negative prejudice against asylum seekers. Keywords: Australian Foreign Policy, Asylum Seeker, Policy Influencer. Abstrak. Penelitian ini membahas tentang policy influencer dalam kebijakan Australia terhadap pencari suaka pada masa pemerintahan Julia Gillard kurun waktu 2010-2013. Pendekatan ini mengikutsertakan penerapan kembali dari kebijakan Solusi Pasifik, pemulangan pencari suaka ke negara asalnya, dan Solusi Malaysia serta kebijakan lainnya. Penelitian ini menggunakan teori sistem pengaruh kebijakan dan teori prasangka dalam menjelaskan kebijakan yang diterapkan oleh pemerintah Australia dalam menangani pencari suaka di tengah pemerintahan Julia Gillard dan komponen di balik pembuatan kebijakan. Pemeringkatan analitis yang digunakan adalah negara-bangsa. Penelitian ini merupakan penelitian kualitatif dengan tipe deskriptif. Hasil penelitian ini menunjukkan bahwa kebijakan Australia terhadap pencari suaka di bawah pemerintahan Gillard dipengaruhi oleh tiga faktor pengaruh kebijakan, yaitu birokrasi, partai, dan masyarakat, yang penuh dengan prasangka negatif terhadap pencari suaka. Kata Kunci: Kebijakan Luar Negeri Australia, Pencari Suaka, Pemberi Pengaruh Kebijakan.