bluuebunny/crossref_metadata_2025_split huggingface dataset:
Estimating Student Attrition in School-Based Prevention Studies: Guidance from State Longitudinal Data in Maryland
Authors: Henneberger Angela K. , Rose Bess A. , Feng Yi , Johnson Tessa , Register Brennan , Stapleton Laura M. , Sweet Tracy , Woolley Michael E. 
Published: May 2023

AbstractAttrition is a critical concern for evaluating the rigor of prevention studies, and the current study provides rates of attrition for subgroups of students and schools who are often sampled for prevention science. This is the first study to provide practical guidance for expected rates of attrition using population-level statewide data; findings indicated that researchers using K-12 school-based samples should plan for attrition rates as high as 27% during middle school and 54% during elementary school. However, researchers should consider the grade levels initially sampled, the length of follow-up, and the specific student characteristics and schools available for sampling. Postsecondary attrition ranged from 45% for bachelor’s degree seekers to 73% for associate degree seekers. This practical guidance can help researchers to proactively plan for attrition in the study design phase, limiting bias and increasing the validity of prevention studies.
Grover search inspired alternating operator ansatz of quantum approximate optimization algorithm for search problems
Authors: Chiang Chen-Fu , Alsing Paul M. 
Published: May 2023

AbstractWe use the mapping between two computation frameworks, Adiabatic Grover Search (AGS) and Adiabatic Quantum Computing (AQC), to translate the Grover search algorithm into the AQC regime. We then apply Trotterization on the schedule-dependent Hamiltonian of AGS to obtain the values of variational parameters in the Quantum Approximate Optimization Algorithm (QAOA) framework. The goal is to carry the optimal behavior of Grover search algorithm into the QAOA framework without the iterative machine learning processes.
History of Incarceration is Associated with Unmet Socioeconomic Needs and Structural Discrimination among Young Black Sexual Minority Men (SMM) in the United States
Authors: Ogunbajo Adedotun , Siconolfi Daniel , Storholm Erik , Vincent Wilson , Pollack Lance , Rebchook Greg , Tan Judy , Huebner David , Kegeles Susan 
Published: May 2023

AbstractThere is a dearth of research on incarceration among young Black sexual minority men (SMM). The current study aimed to assess the prevalence and association between unmet socioeconomic and structural needs and history of incarceration among young Black SMM. Between 2009 and 2015, young Black SMM (N = 1,774) in Dallas and Houston Texas were recruited to participate in an annual, venue-based, cross-sectional survey. We found that 26% of the sample reported any lifetime history of incarceration. Additionally, participants with unmet socioeconomic and structural needs (unemployment, homelessness, financial insecurity and limited educational attainment) were more likely to have a history of incarceration. It is imperative that interventions are developed to address the basic, social, and economic needs of young Black SMM with a history of incarceration or who are at risk for incarceration.
High-Density Linkage Map Constructed from a Skim Sequenced Diploid Potato Population Reveals Transmission Distortion and QTLs for Tuber Yield and Pollen Shed
Authors: Clot Corentin R. , Wang Xulan , Koopman Joey , Navarro Alejandro Thérèse , Bucher Johan , Visser Richard G. F. , Finkers Richard , van Eck Herman J. 
Published: May 2023

Abstract
The reinvention of potato, from a tetraploid clonal crop into a diploid seed-based hybrid crop, requires insight in the mutational load, recombination landscape, and the genetic basis of fertility. Genomics-based breeding and QTL discovery rely on efficient genotyping strategies such as skim sequencing, to gather genotypic information. The application of skim sequencing to full-sib population of non-inbred parents remains challenging. Here, we report on an R implementation of the OutcrossSeq pipeline for diploids. We applied this pipeline to a large diploid skim sequenced potato population. We used the resulting bin-markers for the construction of high-density parent specific linkage maps, highlighting variation in parental recombination rate and structural variations. We subsequently explored transmission ratio distortion and non-independent assortment of alleles, indicative of large-effect deleterious mutations. Finally, we identified QTLs for seedling tuber yield in pots and pollen shed. This study showcases the range of genetic analyses, from marker inference, identification of transmission ratio distortion, and linkage map construction to QTL mapping, resulting in new insights that contribute to breeding diploid potato.
Taxonomy and multigene phylogeny of Pseudohydnum (Auriculariales, Basidiomycota)
Authors: Spirin Viacheslav , Malysheva Vera , Viner Ilya , Dudka Vasiliy , Grebenc Tine , Miettinen Otto 
Published: May 2023

AbstractTaxonomy of Pseudohydnum gelatinosum and its sister taxa is revised via morphological data and a four-gene dataset (ITS, nc LSU rDNA, TEF1, RPB1). Identity of P. gelatinosum and Tremellodon pusillus is re-established based on newly collected and sequenced material from their type localities. Pseudohydnum alienum from Europe; P. umbrosum from temperate East Asia; P. cystidiatum, P. meridianum, and P. placibile from Vietnam; and P. omnipavum from North America are described as new to science; P. translucens and P. brunneiceps from East Asia are redescribed. Most Pseudohydnum collections from North America belong to P. gelatinosum ssp. pusillum. A significant divergence of TEF1 sequences in P. gelatinosum is discussed.
Influence of Ductility on Fracture in Tensile Testing of Cold Gas Sprayed Deposits
Authors: List A. , Huang C. , Wiehler L. , Gieseler C.-P. , Schulze M. , Gärtner F. , Klassen T. 
Published: May 2023

AbstractCold gas spraying nowadays receives much interest for additive manufacturing due to its high deposition rate. Associated structural applications define high requirements regarding mechanical properties and failure tolerances. Up to present, micro-flat tensile (MFT) or tubular coating tensile (TCT) tests are well-established for determining deposit strengths. Due to particular stress states during testing, both provide slightly different information. While MFT tests can provide information on strain and ductility, stress concentration in TCT tests requires to apply a notch factor for calculating the ultimate tensile strength. Here, we suggest that a suitable combination of both tests can provide additional information about tolerances against local stress concentrations in crack initiation and growth. Taking titanium and copper as model systems, results from MFT and TCT tests are evaluated over a wide range of spray parameter sets into regimes that allow for high deposit qualities, even reaching certain ductility. The correlation between the results reveals that the derived stress concentration sensitivity depends on the deposit quality and could eventually decrease to unity. In turn, the correlation to respective strain to failure data can supply information on underlying deformation mechanisms. These preliminary results thus provide strategies for tuning deposit toughness and give prerequisites for quality forecasts.
Clinical and Pathological Features and Gene Expression Profiles of Clinically Aggressive Papillary Thyroid Carcinomas
Authors: Metovic Jasna , Cabutti Francesco , Osella-Abate Simona , Orlando Giulia , Tampieri Cristian , Napoli Francesca , Maletta Francesca , Daniele Lorenzo , Volante Marco , Papotti Mauro 
Published: May 2023

Abstract
Papillary thyroid carcinoma (PTC) is considered an indolent neoplasm but it may demonstrate aggressive behavior. We aimed to identify clinical and pathological characteristics and molecular signatures associated with aggressive forms of PTCs. We selected 43 aggressive PTC cases based on the presence of metastases at the time of diagnosis, the development of distant metastasis during follow-up, and/or biochemical recurrence, and 43 PTC patients that were disease-free upon follow-up, matching them according to age, sex, pT, and pN parameters. Twenty-four pairs (a total of 48 cases) and 6 normal thyroid tissues were studied using targeted mRNA screening of cancer-associated genes employing NanoString nCounter® technology. In general, aggressive PTCs showed distinctive clinical and morphological features. Among adverse prognostic parameters, the presence of necrosis and an increased mitotic index were associated with shorter disease-free and overall survivals. Other parameters associated with shorter disease-free or overall survivals include a lack of tumor capsule, the presence of vascular invasion, tumor-infiltrating lymphocytes, fibrosclerotic changes, age > 55 years, and a high pTN stage. Various pathways were differentially regulated in non-aggressive as compared to aggressive PTC, including the DNA damage repair, the MAPK, and the RAS pathways. In particular, the hedgehog pathway was differentially de-regulated in aggressive PTC as compared to non-aggressive PTC cases, being WNT10A and GLI3 genes significantly up- and down-regulated in aggressive PTC and GSK3B up-regulated in non-aggressive PTC cases. In conclusion, our study revealed specific molecular signatures and morphological features in aggressive PTC that may be useful to predict more aggressive behavior in a subset of PTC patients. These findings may be useful when developing novel, tailored treatment options for these patients.
Aquaporin 4 Mediates the Effect of Iron Overload on Hydrocephalus After Intraventricular Hemorrhage
Authors: Li Ying , Nan Ding , Liu Ran , Li Jieyu , Zhang Zhuangzhuang , Deng Jianwen , Zhang Yang , Yan Ziguang , Hou Chao , Yao Ensheng , Sun Weiping , Wang Zhaoxia , Huang Yining 
Published: May 2023

Abstract
Background
Iron overload plays an important role in hydrocephalus development following intraventricular hemorrhage (IVH). Aquaporin 4 (AQP4) participates in the balance of cerebrospinal fluid secretion and absorption. The current study investigated the role of AQP4 in the formation of hydrocephalus caused by iron overload after IVH.

Methods
There were three parts to this study. First, Sprague–Dawley rats received an intraventricular injection of 100 µl autologous blood or saline control. Second, rats had IVH and were treated with deferoxamine (DFX), an iron chelator, or vehicle. Third, rats had IVH and were treated with 2-(nicotinamide)-1,3,4-thiadiazole (TGN-020), a specific AQP4 inhibitor, or vehicle. Rats underwent T2-weighted and T2* gradient-echo magnetic resonance imaging to assess lateral ventricular volume and intraventricular iron deposition at 7, 14, and 28 days after intraventricular injection and were then euthanized. Real-time quantitative polymerase chain reaction, western blot analysis, and immunofluorescence analyses were conducted on the rat brains to evaluate the expression of AQP4 at different time points. Hematoxylin and eosin–stained brain sections were obtained to assess the ventricular wall damage on day 28.

Results
Intraventricular injection of autologous blood caused a significant ventricular dilatation, iron deposition, and ventricular wall damage. There was increased AQP4 mRNA and protein expression in the periventricular tissue in IVH rats through day 7 to day 28. The DFX treatment group had a lower lateral ventricular volume and less intraventricular iron deposition and ventricular wall damage than the vehicle-treated group after IVH. The expression of AQP4 protein in periventricular tissue was also inhibited by DFX on days 14 and 28 after IVH. The use of TGN-020 attenuated hydrocephalus development after IVH and inhibited the expression of AQP4 protein in the periventricular tissue between day 14 and day 28 without a significant effect on intraventricular iron deposition or ventricular wall damage.

Conclusions
AQP4 located in the periventricular area mediated the effect of iron overload on hydrocephalus after IVH.
Continuum limits for discrete Dirac operators on 2D square lattices
Authors: Schmidt Karl Michael , Umeda Tomio 
Published: May 2023

AbstractWe discuss the continuum limit of discrete Dirac operators on the square lattice in $${\mathbb {R}}^2$$

R

2

as the mesh size tends to zero. To this end, we propose the most natural and simplest embedding of $$\ell ^2({\mathbb {Z}}_h^d)$$

ℓ
2

(

Z
h
d

)

into $$L^2({\mathbb {R}}^d)$$

L
2

(

R

d

)

, which enables us to compare the discrete Dirac operators with the continuum Dirac operators in the same Hilbert space $$L^2({\mathbb {R}}^2)^2$$

L
2

(

R

2

)

2

. In particular, we prove that the discrete Dirac operators converge to the continuum Dirac operators in the strong resolvent sense. Potentials are assumed to be bounded and uniformly continuous functions on $${\mathbb {R}}^2$$

R

2

and allowed to be complex matrix-valued. We also prove that the discrete Dirac operators do not converge to the continuum Dirac operators in the norm resolvent sense. This is closely related to the observation that the Liouville theorem does not hold in discrete complex analysis.
Heat shock protein 70 reflected the state of inhabited fish response to water quality within lake ecosystem
Authors: Rangaswamy B. , Kim W.-S. , Kwak I.-S. 
Published: May 2023

AbstractHeat shock proteins are natural biomarker that plays a vital role in genetic variability and adaptive survival in organisms under environmental stress. We assessed the effect of the stressor using Heat shock protein 70 in Hemibarbus labeo and Lepomis macrochirus at three geological points of Juam and Yedang lake. The study focused on the stress-relieving effect of heat shock protein 70 expressed in fish associated with physicochemical factors in the lake ecosystem. We recorded significant upregulation (p < 0.05) of the heat shock protein 70 gene in L. macrochirus in Juam (0.99-fold) and Yedang (1.44-fold). The upregulation in H. labeo indicated 0.83-fold in Juam and 1.21-fold in Yedang. The water quality index determined using physicochemical factors was low in the middle regions of both lakes. However, the maximum gene expression distribution was found in Yedang. The two-way clustering analysis revealed ammonia, total phosphorus, and suspended solids with maximum stress threshold. Dissolved oxygen, pH, nitrate, and organic carbon were the stress factors with minimal concentrations induced expression. The key observations are (i) the vital influence of molecular markers regulated tolerance at initial stress levels, (ii) the synergistic effect of the stressors and Heat shock protein 70 induction impacted adaptive strategy in fishes to regain tolerance (iii) fish population (L. macrochirus) with elevated response exhibited maximum distribution, correlating with the practical scenario. Heat shock protein 70 expressions through metabolic compensation strategy thus influenced the size of inhabited fish population retarding biodiversity of the lake ecosystem.
Blood-Based Biomarkers for Managing Workload in Athletes: Considerations and Recommendations for Evidence-Based Use of Established Biomarkers
Authors: Haller Nils , Behringer Michael , Reichel Thomas , Wahl Patrick , Simon Perikles , Krüger Karsten , Zimmer Philipp , Stöggl Thomas 
Published: May 2023

AbstractBlood-based biomarkers can provide an objective individualized measure of training load, recovery, and health status in order to reduce injury risk and maximize performance. Despite enormous potentials, especially owing to currently evolving technology, such as point-of-care testing, and advantages, in terms of objectivity and non-interference with the training process, there are several pitfalls in the use and interpretation of biomarkers. Confounding variables such as preanalytical conditions, inter-individual differences, or an individual chronic workload can lead to variance in resting levels. In addition, statistical considerations such as the detection of meaningful minimal changes are often neglected. The lack of generally applicable and individual reference levels further complicates the interpretation of level changes and thus load management via biomarkers. Here, the potentials and pitfalls of blood-based biomarkers are described, followed by an overview of established biomarkers currently used to support workload management. Creatine kinase is discussed in terms of its evidence for workload management to illustrate the limited applicability of established markers for workload management to date. We conclude with recommendations for best practices in the use and interpretation of biomarkers in a sport-specific context.
The association between sport type and eating/body image concerns in high school students: a cross-sectional observational study
Authors: D’Anna Giulio , Lucherini Angeletti Lorenzo , Benvenuti Federica , Melani Giulia , Ferroli Marco , Poli Francesca , Villano Rita Giulia , Ricca Valdo , Rotella Francesco 
Published: May 2023

Abstract
Purpose
Disordered eating and body image concerns are increasingly common among adolescents, possibly representing the underpinning of eating disorders (EDs). This cross-sectional observational study aimed at investigating the relationship between various patterns of sports involvement or inactivity, and the abovementioned psychopathological dimensions.

Methods
All adolescents attending their 3rd–5th Italian grade in a single high school reported their sociodemographic and anthropometric data, their weekly sports involvement, and filled the Eating Disorders Examination Questionnaire 6.0 (EDE-Q), the Body Uneasiness Test, and the Muscle Dysmorphia Disorder Inventory (for boys). Comparisons were performed considering sex, weekly hours of activity, and different sports type (none, individual, or team sports).

Results
Of 744 enrolled students, 522 (70.2%) completed the survey. Girls showed higher underweight rates, preference for inactivity or individual sports, and higher psychometric scores compared to boys. Among girls, no differences were found based on time spent exercising or sports type. Inactive boys displayed worse weight- and shape-based psychopathology, higher body uneasiness, and higher appearance intolerance compared to those who devoted more time to exercise. Among boys, individual and team sports were associated with lower EDE-Q scores compared to inactivity, whereas body uneasiness and appearance intolerance were lower only in team sports.

Conclusions
The study confirms the presence of remarkable sex differences in eating and body concerns of adolescents. Among boys, sports involvement is tied to lower ED psychopathology, and preference for team sports may be associated with reduced concerns. Wider longitudinal studies on will clarify the direction and specificity of these findings.

Level of evidence
Level V—Cross-sectional observational study.
UVA-induced metabolic changes in non-malignant skin cells and the potential role of pyruvate as antioxidant
Authors: Ivanova I. , Bogner C. , Gronwald W. , Kreutz M. , Kurz B. , Maisch T. , Kamenisch Y. , Berneburg M. 
Published: May 2023

AbstractThe exposure to UVA (320–400 nm) irradiation is a major threat to human skin concerning photoaging and carcinogenesis. It has been shown that UVA irradiation can induce reactive oxygen species (ROS) and DNA mutations, such as 8-hydroxydeoxyguanosine. Furthermore, UVA induces the expression of photoaging-associated matrix metalloproteases (MMPs), especially of matrix metalloprotease 1 (MMP 1) and matrix metalloprotease 3 (MMP 3). In addition to this, it was recently shown that UVA-induced ROS also increase glucose metabolism of melanoma cells, however, the influence of UVA on the glucose metabolism of non-malignant cells of the human skin has, so far, not been investigated in detail. Here, we investigated the UVA-induced changes in glucose metabolism and the functional relevance of these changes in primary fibroblasts—normal non-malignant cells of the skin. These cells showed an UVA-induced enhanced glucose consumption and lactate production and changes in pyruvate production. As it has been proposed that pyruvate could have antioxidant properties we tested the functional relevance of pyruvate as protective agent against UVA-induced ROS. Our initial experiments support earlier publications, demonstrating that pyruvate treated with H2O2 is non-enzymatically transformed to acetate. Furthermore, we show that this decarboxylation of pyruvate to acetate also occurs upon UVA irradiation. In addition to this, we could show that in fibroblasts pyruvate has antioxidant properties as enhanced levels of pyruvate protect cells from UVA-induced ROS and partially from a DNA mutation by the modified base 8-hydroxydeoxyguanosine. Furthermore, we describe for the first time, that the interaction of UVA with pyruvate is relevant for the regulation of photoaging-associated MMP 1 and MMP 3 expression.
Graphical abstract
Chaotic tracial dynamics
Authors: Jacelon Bhishan 
Published: May 2023

Abstract
The action on the trace space induced by a generic automorphism of a suitable finite classifiable

${\mathrm {C}^*}$

-algebra is shown to be chaotic and weakly mixing. Model

${\mathrm {C}^*}$

-algebras are constructed to observe the central limit theorem and other statistical features of strongly chaotic tracial actions. Genericity of finite Rokhlin dimension is used to describe

$KK$

-contractible stably projectionless

${\mathrm {C}^*}$

-algebras as crossed products.
The role of team compassion in mitigating the impact of hierarchical bullying
Authors: Farr-Wharton Ben , Simpson Ace Volkmann , Brunetto Yvonne , Bentley Tim 
Published: May 2023

AbstractHierarchical bullying in public healthcare organizations is an entrenched negative behaviour that results in a range of adverse outcomes for staff, including diminished wellbeing. This study integrates social exchange and conservation of resources theories as a lens for formulating hypotheses and employs multilevel statistical modelling to examine whether team-level compassion moderates the impact of hierarchical bullying on wellbeing. Using multilevel statistical modelling, the study analysed cross-sectional data from 632 healthcare workers nested within 48 teams in a single public health district in Australia. The findings indicate that work teams with higher levels of team compassion can mitigate the negative effects of hierarchical bullying on employee wellbeing. The results imply that investing in developing compassion within teams is an effective strategy for mitigating some harmful effects of hierarchical bullying on employee outcomes.
Aspiration Versus Apprehension: Economic Opportunities and Electoral Preferences
Authors: Häusermann Silja , Kurer Thomas , Zollinger Delia 
Published: May 2023

AbstractRecent studies take increasingly refined views of how socioeconomic conditions influence political behaviour. We add to this literature by exploring how voters' prospective evaluations of long-term economic and social opportunities relate to electoral contestation versus the stabilization of the political-economic system underpinning the knowledge society. Using survey data from eight West European countries, we show that positive prospects are associated with higher support for mainstream parties (incumbents and opposition) and lower support for radical parties on all levels of material well-being. Our results support the idea that ‘aspirational voters’ with positive evaluations of opportunities (for themselves or their children) represent an important stabilizing force in advanced democratic capitalism. However, we also highlight the importance of radical party support among ‘apprehensive voters’, who are economically secure but perceive a lack of long-term opportunities. To assess the implications of these findings, we discuss the relative importance of these groups across different countries.