bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pragmatic fidelity measurement in youth service settings
Authors: Wang Lu , Stoll Samantha J. , Eddy Christopher J. , Hurley Sarah , Sisson Jocelyn , Thompson Nicholas , Raftery-Helmer Jacquelyn N. , Ablon J. Stuart , Pollastri Alisha R. 
Published: July 2023

Background Fidelity measurement is critical for developing, evaluating, and implementing evidence-based treatments (EBTs). However, traditional fidelity measurement tools are often not feasible for community-based settings. We developed a short fidelity rating form for the Collaborative Problem Solving (CPS) approach from an existing manualized coding system that requires extensive training. We examined the reliability and accuracy of this short form when completed by trained observers, untrained observers, and self-reporting providers to evaluate multiple options for reducing barriers to fidelity measurement in community-based settings. Methods Community-based treatment providers submitted recordings of youth service sessions in which they did, or did not, use CPS. For 60 recordings, we compared short-form fidelity ratings assigned by trained observers and untrained observers to those provided by trained observers on the manualized coding system. For 141 recordings, we compared providers’ self-reported fidelity on the short form to ratings provided by trained observers on the manualized coding system and examined providers’ accuracy as a function of their global fidelity. Results & Conclusions: The short form was reliable and accurate for trained observers. An assigned global integrity score and a calculated average of component scores on the short form, but not component scores themselves, were reliable and accurate for observers who had CPS expertise but no specific training on rating CPS fidelity. When providers self-reported fidelity on the short form, their global integrity score was a reliable estimate of their CPS integrity; however, providers with better CPS fidelity were most accurate in their self-reports. We discuss the costs and benefits of these more pragmatic fidelity measurement options in community-based settings.
Debate: differences and similarities between tension-type headache and migraine
Authors: Onan Dilara , Younis Samaira , Wellsgatnik William David , Farham Fatemeh , Andruškevičius Saulius , Abashidze Ana , Jusupova Asel , Romanenko Yuriy , Grosu Oxana , Moldokulova Meerimgul Zamirbekovna , Mursalova Ulkar , Saidkhodjaeva Saida , Martelletti Paolo , Ashina Sait 
Published: July 2023

AbstractTension-type headache (TTH) and migraine are two common primary headaches distinguished by clinical characteristics according to the 3rd edition of the International Classification of Headache Disorders. Migraine is identified by specific features such as being more prevalent in females, being aggravated by physical activity, certain genetic factors, having photophobia, phonophobia, nausea, vomiting, or aura, and responding to specific drugs. Nonetheless, TTH and migraine share some common characteristics, such as onset occurring in the 20 s, and being triggered by psychological factors like stress, moderate pain severity, and mild nausea in chronic TTH. Both conditions involve the trigeminovascular system in their pathophysiology. However, distinguishing between TTH and migraine in clinical practice, research, and epidemiological studies can be challenging, as there is a lack of specific diagnostic tests and biomarkers. Moreover, both conditions may coexist, further complicating the diagnostic process. This review aims to explore the similarities and differences in the pathophysiology, epidemiology, burden and disability, comorbidities, and responses to pharmacological and non-pharmacological treatments of TTH and migraine. The review also discusses future research directions to address the diagnostic challenges and improve the understanding and management of these conditions.
Graphical Abstract
Is vitamin D supplementation program in Iranian schools effective in reducing adolescent depressive symptoms? Cost effectiveness study
Authors: Jasemi Seyed Vahid , Zandieh Zhale , Zandieh Narges , Hemami Mohsen Rezaei , Darvishi Ali , Abdollahi Zahra , Heshmat Ramin 
Published: July 2023

AbstractPurposeWe aimed to assess the cost-effectiveness of the vitamin D supplementation program in Iranian adolescents reducing adolescent depressive Symptoms.MethodsIn the current cost-effectiveness analysis, the viewpoint of Iran’s Ministry of Health was selected. The target population was 1,519,762 Iranian high school students (733,657 girls and 786,105 boys). The total costs of the vitamin D supplementations program were based on the reports of the Nutrition Improvement Office of Iran’s Ministry of Health and were adjusted to 2018. The variable of Quality-Adjusted Life Years (QALYs) was considered a suitable variable for estimating the effectiveness of vitamin D supplementation. We chose one year as the time horizon. A decision tree model was constructed in TreeAge Pro. The results of the cost-effectiveness analysis were reported in term of the Incremental Cost-Effectiveness Ratio (ICER).ResultsThe results of our study showed that the estimated cost per QALY gained of the vitamin D supplementation program is equal to 1528.6676 $, which indicates that vitamin D supplementation in adolescents(11-18Y) is a cost-effective and a dominant strategy in preventing depression through the cost-saving and QALYs increment compared to the no intervention. Sensitivity analysis showed that the possible variations in vitamin D supplement costs could not alter the results, and vitamin D supplementation may be a predominant and cost-effective strategy to prevent adulthood depression with a 100% probability.ConclusionThe national program of vitamin D supplementation among Iranian adolescents was a cost-efficient strategy reducing adolescent depressive Symptoms through the cost-saving and QALYs increment compared to the no intervention.
Community perspectives and experiences of quality maternal and newborn care in East New Britain, Papua New Guinea
Authors: Wilson Alyce N. , Melepia Pele , Suruka Rose , Hezeri Priscah , Kabiu Dukduk , Babona Delly , Wapi Pinip , Morgan Alison , Vogel Joshua P. , Beeson James , Morgan Christopher , Kelly-Hanku Angela , Scoullar Michelle J. L. , Nosi Somu , Vallely Lisa M. , Kennedy Elissa , Bohren Meghan A. , Homer Caroline S. E. 
Published: July 2023

Abstract
Background
Quality maternal and newborn care is essential for improving the health of mothers and babies. Low- and middle-income countries, such as Papua New Guinea (PNG), face many barriers to achieving quality care for all. Efforts to improve the quality of maternal and newborn care must involve community in the design, implementation, and evaluation of initiatives to ensure that interventions are appropriate and relevant for the target community. We aimed to describe community members’ perspectives and experiences of maternal and newborn care, and their ideas for improvement in one province, East New Britain, in PNG.

Methods
We undertook a qualitative descriptive study in partnership with and alongside five local health facilities, health care workers and community members, using a Partnership Defined Quality Approach. We conducted ten focus group discussions with 68 community members (identified through church, market and other community-based groups) in East New Britain PNG to explore perspectives and experiences of maternal and newborn care, identify enablers and barriers to quality care and interventions to improve care. Discussions were transcribed verbatim. A mixed inductive and deductive analysis was conducted including application of the World Health Organisation (WHO) Quality Maternal and Newborn Care framework.

Results
Using the WHO framework, we present the findings in accordance with the five experience of care domains. We found that the community reported multiple challenges in accessing care and facilities were described as under-staffed and under resourced. Community members emphasised the importance of good communication and competent, caring and respectful healthcare workers. Both women and men expressed a strong desire for companionship during labor and birth. Several changes were suggested by the community that could immediately improve the quality of care.

Conclusions
Community perspectives and experiences are critical for informing effective and sustainable interventions to improve the quality of maternal and newborn care and increasing facility-based births in PNG. A greater understanding of the care experience as a key component of quality care is needed and any quality improvement initiatives must include the user experience as a key outcome measure.
Green approach for the synthesis of ZnO nanoparticles using Cymbopogon citratus aqueous leaf extract: characterization and evaluation of their biological activities
Authors: Abdelbaky Ahmed S. , Mohamed Abir M. H. A. , Sharaky Marwa , Mohamed Nira A. , Diab Yasser M. 
Published: July 2023

Abstract
Background
The green synthesis of metal and metal oxide nanoparticles (NPs), notably from plants, has attracted increasing attention in recent years. Although the increased popularity use of Cymbopogon citratus as a therapeutic substance, to date, there has not been any research on the chemistry of C. citratus aqueous leaf extract (ALE) or synthesis of ZnO NPs utilizing an extract from it. The ecologically safe ALE of C. citratus was employed in this study as a bio-reducing and capping agent to synthesize ZnO NPs.

Results
The novelty of the current study is the investigation of the antioxidant, anti-inflammatory, anti-microbial, and cytotoxic potencies of biosynthesized ZnO NPs utilizing C. citratus ALE. Zinc acetate dihydrate was used as the precursor and the leaf extract serves as the reducing agent. ZnO NPs from ALE of C. citratus were characterized by the spherical in form by using high-resolution transmission electron microscopy (HR-TEM) and the Scherrer formula was used to calculate the size of the crystalline structure. The presence of numerous functional groups in both the ALE and the NPs is confirmed by FTIR analysis. The highest absorption peak is observed at 370 nm. The stability and particle size of the biosynthesized ZnO NPs are demonstrated by dynamic light scattering (DLS) analysis. The biosynthesized ZnO NPs exhibited excellent antioxidant activity with an IC50 value of 45.67 ± 0.1 μg/mL and exerted interesting anti-inflammatory activity (98.1% ± 0.04) when compared to the standard indomethacin (92.1% ± 0.07) at 1 mg/mL. They also showed anti-microbial activity for both bacterial and fungal which growth rates for both significantly decreased with the increase in ZnO NPs concentration compared to the control. The anticancer activity of biosynthesized ZnO NPs and C. citratus ALE was in vitro tested against seven human cancer cell lines (HCCL) (i.e. H1299, MDA-MB-468, HNO97, HEK, HCT116, HuH7, and HEPG2) compared to normal cells (HSF) using the sulforhodamine-B (SRB) assay. More interestingly, the biosynthesized ZnO NPs displayed remarkable selective cytotoxicity against all tested cancer cell lines without any effect on normal cells. In contrast, the cancer cell lines were not affected by the ALE of C. citratus at any concentrations tested.

Conclusions
All the findings confirm that the ZnO NPs biosynthesized in the current work are promising candidates for a variety of biological activities, and as a result, they can be helpful to the medical sector, environmental and agricultural applications.

Graphical Abstract
Clients’ perspectives on the utilization of reproductive, maternal, neonatal, and child health services in primary health centers during COVID-19 pandemic in 10 States of Nigeria: A cross-sectional study
Authors: Adelekan Babatunde , Goldson Erika , Ntoimo Lorretta Favour C. , Adonri Osaretin , Aliyu Yakubu , Onoja Matthew , Araoyinbo Idowu , Anakhuekha Emilene , Mueller Ulla , Ekwere Eno-Obong , Inedu Micheal , Moruf Olayinka , Swomen George , Igboin Brian , Okonofua Friday E. 
Published: July 2023

BackgroundReports from various parts of the world suggest that the COVID-19 pandemic may have severe adverse effects on the delivery and uptake of reproductive health, maternal, neonatal, and child health (RMNCH) services. The objective of the study was to explore women’s experiences with utilization of RMNCH services during the COVID-19 pandemic in Nigeria, and to elicit their perceptions on ways to sustain effective service delivery during the pandemic.MethodsA cross-sectional survey of 2930 women using primary health care facilities for antenatal, delivery, postnatal, and child care services before and after the onset of the pandemic in 10 States of Nigeria were interviewed with a semi-structured questionnaire. Data were collected on women’s socio-demographic characteristics and pregnancy histories, the services they sought before and after the pandemic, the challenges they faced in accessing the services, their use of alternative sources of health care, and their recommendations on ways to sustain RMNCH service delivery during the pandemic. The data were analyzed with descriptive statistics, and multivariable logistic regression using SPSS 20.0. All the statistical analyses were two-tailed with a 95% confidence interval, and the p-value was set at 0.05.ResultsThe logistic regression results showed that women were at least 56% more likely to report that they used family planning, antenatal, and delivery services before the pandemic than after the pandemic started, but 38% less likely to report use of postnatal services. The experience of difficulty accessing RMNCH services was 23% more likely after the pandemic started than before the pandemic. Three categories of recommendations made by the respondents on measures to sustain RMNCH delivery during the pandemic included 1) facility improvement, and staff recruitment and re-training; 2) free and readily accessible PHC services, and 3) the provision of social safety nets including transportation and palliatives.ConclusionWe conclude that the COVID-19 pandemic limited women’s access to antenatal, delivery, and childcare services offered in PHCs in Nigeria. Addressing the recommendations and the concerns raised by women will help to sustain the delivery of RMNCH services during the COVID-19 pandemic and future epidemics or health emergencies in Nigeria.
Global long-term trends and spatial cluster analysis of pancreatic cancer incidence and mortality over a 30-year period using the global burden of disease study 2019 data
Authors: Amini Maedeh , Azizmohammad Looha Mehdi , Rahimi Pordanjani Sajjad , Asadzadeh Aghdaei Hamid , Pourhoseingholi Mohamad Amin 
Published: July 2023

IntroductionPancreatic cancer (PC) is one of the most fatal malignancies, and its incidence and mortality rates are growing annually throughout the world. In this research, we aimed to investigate the time trends and identify the spatial clusters of incidence and mortality on a global scale over the last 30 years, using the Global Burden of Disease (GBD) study 2019 data.MethodsAge-standardized incidence and mortality data due to PC were extracted from the GBD study, which was carried out from 1990 to 2019. A Joinpoint regression analysis was utilized to examine trends in the incidence and mortality of PC over the past three decades. As such, spatial analyses were undertaken to detect the spatial distribution and clustering of the metrics globally.ResultsIt was observed that both the incidence and mortality rates were higher in males than in females worldwide. The global mortality and incidence rates significantly increased by 0.8% per year over the time of follow-up period (p<0.05). By spatial cluster analysis for mortality, European and North African countries, as well as Greenland were explored as hot spots; while South African and Southeast Asian countries were explored as cold spots. Regarding incidence, hot spots were found in European countries, Southern America, and Greenland; whilst cold spots were determined in Southern Africa and Madagascar.ConclusionsCollectively, the temporal trends disclosed a gradual rise in PC incidence and mortality rates over the period 1990–2019, reflecting the global health concern. We further found geographical variations in the patterns and identified high- and low-risk areas for incidence and mortality. These findings facilitate the design and implementation of more resource-efficient and geographically targeted treatments. Given the results of the current study, a practical approach to minimizing the future PC burden involves planned population-wide interventions, as well as primary prevention through healthier lifestyles.
Exploring factors influencing nurses’ attitudes towards their role in dental care
Authors: Gaffar Balgis , Bakhurji Eman , AlKhateeb Reem , AlHashim Hussain , AlGaoud Hadeel , AlDaamah Ziyad , AlSaleh Jamal , Aldamanhori Rand , AlHamid Shahad , AlBarrak Alanoud , Siddiqui Intisar Ahmad , Virtanen Jorma I. 
Published: July 2023

BackgroundThe burden of oral disease requires collaboration between health care professionals. Nurses are frequently exposed to patients and can play a vital role in prevention of oral diseases. This study aimed to investigate nurses’ attitudes towards their role in dental care and its associated factors.MethodsThis cross-sectional, survey-based study recruited a total of 525 nurses in Eastern Saudi Arabia, using a snow-ball sampling technique. Data was collected using an online, pre-validated 40-item questionnaire with four domains (attitudes, knowledge, practices, and demographic data).ResultsNurses showed satisfactory attitudes (52.8 ± 8.2) and average knowledge (13.4 ±3.9). More than two thirds (70.3%) reported responding to patients’ questions about oral health conditions, 47.1% and 19.7% conducted oral health screening and education respectively. Referral practices were reported by 266 (50.7%) of the participants with pain being the main reason for referrals. Attending lectures/ trainings on oral health and having a formal education about oral health were significantly associated with nurses’ positive attitudes towards their role in dental care (P<0.001). Conducting oral health screening or education were also significantly associated with positive attitudes (P = 0.001).ConclusionPositive attitudes were observed among those with undergraduate oral health backgrounds, in continuous education, and those who were involved in oral health screenings. There is a need for under and postgraduate inclusion of oral health training in nurses’ education.
Risk identification of PPP mode in stadiums and gymnasiums by ant colony algorithm
Authors: Qin Rongrong , Zhao Min 
Published: July 2023

Aiming at the problem that the PPP model of stadiums and gymnasiums can not realize multi-dimensional risk analysis and the global risk identification ability is poor, an ant colony algorithm is proposed. Firstly, k clustering is used to cluster PPP mode data. Then, the ant colony algorithm is analyzed stochastically, and the risk set of PPP mode is obtained, which lays the foundation for later risk identification. Finally, through the random fusion function, the PPP mode risk set based on the path profile is constructed, and the optimal identification path is obtained, so as to improve the identification accuracy of PPP mode risk. MATLAB simulation shows that the ant colony algorithm proposed in this paper is superior to the risk clustering method in the overall risk identification accuracy and identification time of PPP mode. Therefore, the ant colony algorithm proposed in this paper can be used to identify the risk of PPP mode, to meet the needs of the construction of stadiums and gymnasiums.
Best Practice Guru TK Jakarta Pada Pembelajaran Ecoliteracy
Authors: Siregar Ilias Nasaruddin , Budiarti Erna 
Published: July 2023

Tujuan dari penelitian ini untuk mendeskripsikan best practice Guru TK Jakarta pada ecoliteracy. Metode penelitian kualitatif dengan subjek 11 guru ada TK Provinsi Jakarta. Teknik pengumpulan data melalui survey mengunakan googleform. Analisa data mengunakan reduksi, penyajian data dan kesimpulan. Hasil penelitian ini adalah Guru TK di provinsi Jakarta telah mengetahui makna ecoliteracy dan menyadari pentingnya membangun kesadaran ecoliteracy. Pengalaman untuk menumbuhkan kesadaran ecoliteracy dipraktekan maupun dilakukan dalam pembelajaran di kelas. Media yang digunakan berupa media visual, audio-visual maupun barang-barang asli. Guru juga memberikan contoh dalam membangun kesadaran ecoliteracy
Prompt closure versus gradual weaning of external ventricular drainage for hydrocephalus following aneurysmal subarachnoid haemorrhage:
a statistical analysis plan for the DRAIN randomised clinical trial
Authors: Capion Tenna , Lilja-Cyron Alexander , Juhler Marianne , Møller Kirsten , Sorteberg Angelika , Rønning Pål André , Poulsen Frantz Rom , Wismann Joakim , Schack Anders Emil , Ravlo Celina , Isaksen Jørgen , Lindschou Jane , Gluud Christian , Mathiesen Tiit , Olsen Markus Harboe 
Published: July 2023

Abstract

Background: Insertion of an external ventricular drain (EVD) is a first-line treatment of acute hydrocephalus caused by aneurysmal subarachnoid haemorrhage (aSAH). Once the patient is clinically stable, the EVD is either removed or replaced by a permanent internal shunt. The optimal strategy for cessation of the EVD is unknown. Prompt closure carries a risk of acute hydrocephalus or redundant shunt implantations, whereas gradual weaning may increase the risk of EVD-related infections.
Methods: DRAIN (Danish RAndomised Trial of External Ventricular Drainage Cessation IN Aneurysmal Subarachnoid Haemorrhage) is an international multicentre randomised clinical trial comparing prompt closure versus gradual weaning of the EVD after aSAH. The primary outcome is composite of VP-shunt implantation, all-cause mortality, or EVD-related infection. Secondary outcomes are serious adverse events excl. mortality and health-related quality of life (EQ-5D-5L). Exploratory outcomes are modified Rankin Scale, Fatigue Severity Scale, Glasgow Outcome Scale Extended, and length of stay in the neurointensive care unit and hospital. Outcome assessment will be performed 6 months after ictus. Based on the sample size calculation (event proportion 80% in the gradual weaning group, relative risk reduction 20%, alpha 5%, power 80%) 122 participants are required in each intervention group. Outcome assessment for the primary outcome, statistical analyses, and conclusion drawing will be blinded. Two independent statistical analyses and reports will be tracked using a version control system, and both will be published. Based on the final statistical report, the blinded Steering Group will formulate two abstracts.
Conclusion: We present a pre-defined statistical analysis plan for the randomised DRAIN trial, which limits bias, p-hacking, and data-driven interpretations. This statistical analysis plan is accompanied by tables with simulated data, which increases transparency and reproducibility.
Trial registration: ClinicalTrials.gov identifier: NCT03948256