bluuebunny/crossref_metadata_2025_split huggingface dataset:
Key Success Factors in Maternity Waiting Home Implementation: A Qualitative Study in Rural Indonesia
Authors: Wenang Supriyatiningsih , Dewi Arlina , Emilia Ova , Febrianti Lidia , Haier Joerg 
Published: April 2023

Abstract

BackgroundMaternal mortality remains a major challenge to health systems worldwide. One of its main causes is the limited number of health workers and facilities for pregnant women in rural areas. To reduce maternal mortality rates, Indonesia has instated policies to support the implementation of Maternity Waiting Homes (MWHs). Bulukumba District is located in an MWHs implementation area and is representative of the mainland and ocean countryside. Thus, the Bulukumba District was used in this study to investigate the key success factors in MWHs implementation.MethodsThis is a qualitative study with an exploratory approach. This research was conducted in Bulukumba, South Sulawesi, a rural area in Indonesia, in 2020. Data was collected through focus group discussions (FGD) involving public and civil parties (n = 10), government members (n = 14), professional organizations (n = 8), and local community members (n = 12). The NVivo Release 1.0 software was used in this study’s analysis to code and categorize the transcripts.ResultsThree themes were identified: stakeholders’ experience in managing MWHs in rural areas, efforts to increase the implementation of MWHs by stakeholders, and stakeholder expectations regarding the implementation of MWHs.ConclusionsThe key success factors in MWH implementation are leadership and collaboration with each stakeholder. Additionally, the stakeholders’ experiences, efforts, and expectations of MWH implementation can decrease the maternal mortality rate in rural areas.
Bilateral Hashing model of ECG signal encryption system using Downhill Peak Follow (DPF) based Encryption technique
Authors: AN Sanjeev kumar , B Ramesh Naik 
Published: April 2023

Abstract

This research suggests a unique ECG security solution based on the data pattern-based encryption paradigm to address security issues in ECG signal transmission or storage environments. According to this concept, the encryption system controls the data security process by extracting key signatures from the ECG signal peaks to identify the characteristics or attributes of the data and encrypt it. To estimate the hashing qualities, the approach is to build a random key pattern based on the signal peaks and extract the signature. The signal was then encrypted and sent to a doctor or signal analyzer. The Bilateral Random Hashing (BRH) is used to achieve this. This updates the hashing generation model by analyzing the parameters using probabilistic distributional characteristics. This crucial motif was applied. This key pattern was utilized to encrypt the data samples using the Downhill Peak Follow (DPF) encryption technique, which follows the strength of the peak value in the ECG waveform. This suggested project is carried out using MATLAB scripting.
Fertility and fecundity in the Australian sheep flock
Authors: Refshauge G. , Golledge M. , Rickard J. , de Graaf S. 
Published: April 2023

Abstract

After decades of decline, the Australian sheep flock aspires to rebuild its population of breeding ewes. A successful, rapid rebuild will rely on high pregnancy rates and number of lambs born and reared. To examine this potential, historical pregnancy scanning records were collated from two experienced sheep pregnancy scanning businesses (years 2006 to 2019) from 15,397 mobs of ewes, totalling 7,443,314 ewes. Client details were de-identified and excluded from analyses, but when available details describing the mobs were retained, such as season of mating, production zone, ewe age, and breed. The key finding was a mean pregnancy rate (ewes pregnant per ewe scanned) of 0.76 ± 0.24, with a median of 0.83. Mobs scanned for litter size had a higher mean (0.84 ± 0.15) and median (0.89) pregnancy rate. The mean reproduction rate (fetuses per ewe scanned) was 1.21 ± 0.27 and the median was 1.25. None of the factors including age, breed, season, year or production zone explained the low overall mean pregnancy rate. The unexpected findings imply a problem exists with the fertility of many Australian sheep flocks and that pregnancy rate is a clear constraint on flock rebuilding aspirations.
Biological and molecular characterization of HCB-289: a Brazilian head and neck cancer stem-like cell line
Authors: Melendez Matias Eliseo , Silva-Oliveira Renato José , Evangelista Adriane Feijó , Pelloso Ana Rubia Alcantara , Arantes Lidia Maria Rebolho , Reis Rui Manuel , De Carvalho Ana Carolina , Carvalho André Lopes 
Published: April 2023

Abstract
In the present study, we describe the establishment of a Brazilian primary laryngeal HNSCC cell line, HCB-289, and isolated a putative cancer stem-like cell subpopulation. Primary cell culture was established from a mechanically disrupted fresh tumor by adherence to cell culture flask. Tumor cells were enriched by fibroblast elimination via differential trypsinization. After establishment, a CD44HIGH /ALDHHIGH subpopulation was isolated and purified from the parental HCB-289 cells by cell sorting. The CD44HIGH /ALDHHIGH proliferation rates and lower sensitivity to cisplatin, paclitaxel, cetuximab, and allitinib than its CD44LOW /ALDHLOW counterpart. Moreover, nanoString subpopulation exhibited greater clonogenic potential, lower miRNome analysis of these two subpopulations showed a higher expression of has-miR-205-5p CD44HIGH /ALDHHIGH and a lower expression of has-miR146a-5p (ratio = 0.08) in the subpopulation (ratio = 35.37). This novel study model will help in the understanding of the biology and molecular features of larynx squamous cell carcinoma, and its chemotherapeutic resistance.
Implications:Our study established and characterized a new cell lineage from the Brazilian population derived from a solid primary tumor of the laryngeal HNSCC primary cell line and can be a useful tool for studying laryngeal squamous cell carcinoma
Psychological impact of the Northern Ethiopia Civil war on Tigray Athletes
Authors: Gebretensay Mulay , Legesse Kesatie , Kiflom Saymon 
Published: April 2023

Abstract

Background:The civil war in northern Ethiopia (November 4, 2020 – November 2, 2022) caused unimaginable suffering to the people of Tigray. Psychological suffering is among the many. It is well known that war affects all people living in the war zone and alters life dramatically, as its effects can be both physical injury of varying degrees of severity and the dangerous invisible wounds caused by psychological trauma and stress. As far as this issue is concerned, numerous research results have shown the psychological impact of war on the general population. However, no research has been carried out on the psychological impact of war on athletes. So the main objective of this study was to assess the psychological impact of the Northern Ethiopia civil war on Tigray Athletes.
Methods: To achieve the purpose of this study, a total of 144 athletes from various clubs in the Tigray area were selected using the convenience sampling method. The anxiety symptom was assessed using the Generalized Anxiety Disorder Scale (GAD-7) and the depression symptom was assessed using the Centre for Epidemiologic Studies (CES-D) depression scale. The data gathered was analyzed using the SPSS statistical package (version 25 for Windows).
Results: Of 144 participants, 1 (0.7%) showed minimal anxiety; 4 (2.8%) showed mild anxiety; 29 (20.1%) showed moderate anxiety; and 110 (76.4%) showed severe anxiety. And regarding depression, all of the participants were shown symptoms of depression as their score was higher than 16 points.
Conclusions: As the result shows, almost all participants have a risk of anxiety and depression. It can thus be concluded that the two-year civil war in northern Ethiopia had a negative psychological impact on Tigray athletes.
Total knee arthroplasty using the Midvastus approach with a half tourniquet facilitate recoveries better： a retrospective study
Authors: Liu Wangxin , Pan Zhicheng , Sun Anqi , Sun Huihui , Liu Lei , Li Huajie , Zhang Yang 
Published: April 2023

Abstract

PurposeThis research aimed to compare recovery outcomes in patients undergoing total knee arthroplasty(TKA) with a half-course tourniquet using the midvastus(MV) approach and the medial parapatellar(MP) approach.MethodsPatients receiving TKA treatment (MV or MP) were retrospectively recruited in this study between June 2019 to June 2022. The demographic, perioperative, and patient satisfaction data were collected and compared between MV and MP groups.ResultsA retrospective study of 112 patients who underwent total knee replacement between June 2019 and June 2022 was divided into two groups according to different surgical approaches, including the MV approach (59 cases) and the MP approach (53 cases). General data (age, sex, height, weight, BMI, education level, VAS score, HSS score), intraoperative data(incision length, operation time, intraoperative blood loss) and postoperative data(postoperative drainage volume, hemoglobin difference before and after surgery, time of first postoperative landing, postoperative hospital stay, VAS score and HSS score in the first week, one month and three months after surgery), as well as the number of blood transfusion cases, the number of surgical complications, and satisfaction were collected.ConclusionsBoth the midvastus approach and the medial parapatellar approach were able to complete the knee replacement and improve the patients’ knee function, and the medial femoral approach was beneficial for the patients’ early recovery, but there was no significant difference in knee function, complications, and satisfaction between the two groups at 3 months after surgery.
Permissioned Blockchain Network for Proactive Access Control to Electronic Health Records
Authors: Psarra Evgenia , Apostolou Dimitris , Verginadis Yiannis , Patiniotakis Ioannis , Mentzas Gregoris 
Published: April 2023

Abstract

Background As digital healthcare services handle increasingly more sensitive health data, robust access control methods are required. Especially in emergency conditions, where the patient’s health situation is in peril, different healthcare providers associated with critical cases may need to be granted permission to acquire access to Electronic Health Records (EHRs) of patients. The research objective of our work is to develop a proactive access control method that can grant emergency clinicians access to sensitive health data, guaranteeing the integrity and security of the data, and generating trust without the need for a trusted third party.Methods To enable proactivity, we apply Long Short Term Memory (LSTM) Neural Networks (NNs) that utilize patient’s recent health history to prognose the next two-hour health metrics values. Fuzzy logic is used to evaluate the severity of the patient’s health state. These techniques are incorporated in a private and permissioned Hyperledger-Fabric blockchain network, capable of securing patient’s sensitive information in the blockchain network.Results Integrating this predictive mechanism within the blockchain network proved to be a robust tool to enhance the performance of the access control mechanism. Furthermore, our blockchain network can record the history of who and when had access to a specific patient’s sensitive EHRs, guaranteeing the integrity and security of the data.Conclusions Our proposed mechanism informs proactively the emergency team about patients’ critical situations by combining fuzzy and predictive techniques, and it exploits the distributed data of the blockchain network, guaranteeing the integrity and security of the data, and enhancing the users’ trust to the mechanism.
Artificial intelligence redefines RNA virus discovery
Authors: Shi Mang , Hou Xin , He Yong , Fang Pan , Mei Shi-Qiang , Xu Zan , Wu Wei-Chen , Tian Jun-hua , Zhang Shun , Zeng Zhen-Yu , Gou Qin-Yu , Xin Gen-Yang , Le Shi-Jia , Xia Yinyue , Zhou Yu-Lan , Hui Feng-Ming , Pan Yuan-Fei , Eden John-Sebastian , Yang Zhaohui , Han Chong , Shu Yuelong , Guo Deyin , Li Jun , Holmes Edward , Li Zhaorong 
Published: April 2023

Abstract
RNA viruses are diverse components of global ecosystems. The metagenomic identification of RNA viruses is currently limited to those with sequence similarity to known viruses, such that highly divergent viruses that comprise the "dark matter" of the virosphere remain challenging to detect. We developed a deep learning algorithm – LucaProt – to search for highly divergent RNA-dependent RNA polymerase (RdRP) sequences in 10,487 global meta-transcriptomes. LucaProt integrates both sequence and structural information to accurately and efficiently detect RdRP sequences. With this approach we identified 180,571 RNA viral species and 180 superclades (viral phyla/classes). This is the broadest diversity of RNA viruses described to date, including many viruses undetectable using BLAST or HMM approaches. The newly identified RNA viruses were present in diverse ecological niches, including the air, hot springs and hydrothermal vents, and both virus diversity and abundance varied substantially among ecological types. We also identified the longest RNA virus genome (nido-like) observed so far, at 47,250 nucleotides, and expanded the diversity of RNA bacteriophage to more than ten phyla/classes. This study marks the beginning of a new era of virus discovery, with the potential to redefine our understanding of the global virosphere and reshape our understanding of virus evolutionary history.
Effect of Sun and Microwave Drying on the Antioxidant Potential and Hydroxymethylfurfural Formation of Damson Plum (Prunus domestica subsp. Insititia)
Authors: Yıldız Dilay , Çağındı Özlem 
Published: April 2023

Abstract

In this study, the antioxidant potential and hydroxymethylfurfural formation of damson plum were investigated using different drying methods. Before drying, the samples were immersed in 1% NaOH at 55°C for 1 min and divided into two groups (half and whole) and dried under the sun and using different microwave power levels (450, 720, 900 W) to reduce the moisture content to 18%. Total dry matter, drying period, total monomeric anthocyanin, total flavonoid, total phenolic, antioxidant capacity and hydroxymethylfurfural values were determined. The sun-drying period of whole plums found to be about four times longer than half plums. Similarly, at different microwave power levels (450, 720 and 900 W), the drying period of whole plums was also longer than half plums, but the sun drying for whole plums was more than 500 times longer and 150 times longer than microwave drying for half plums. Also, the increase in microwave power level shortened the time. The total anthocyanin, total flavonoids, total phenolic and antioxidant capacity values of sun-dried samples were lower than those of microwave-dried samples. It was observed that hydroxymethylfurfural values in microwave-dried samples increased. It is thought that microwave drying at 900 W, where the antioxidant properties of plums dried at three power levels are better preserved, can be recommended with little difference in drying period in 720 W microwave application.
Effect of different production techniques on the color of porcelain-fused-to-titanium restorations
Authors: Korkmaz Cumhur , Atay Arzu 
Published: April 2023

Abstract
Background The aim of the study was to compare the effects of different framework production techniques used in porcelain-fused-to-titanium restorations on color changes.Methods Forty-five square specimens were produced using cast, milling, and laser-sintering techniques. Opaque and dentin porcelain were implemented, and all frameworks glazed. Color measurements were made with a spectrophotometer at before and after opaque application and after porcelain + glaze application, and L*, a*, b* values were obtained. Color difference analyses (ΔE00) were made using the CIEDE2000 formula. Shapiro Wilks (Normality) and ANOVA (Post Hoc:Bonferroni) tests were used to analyze the data (p < 0.05).Results At the different laboratory steps, the difference between cast&laser-sintered groups and between milled&laser-sintered groups were statistically significant (p < 0.05). Before and after opaque application, the differences in L*, a*, and b* values between cast, milled and laser-sintered groups were found a statistically significant (p < 0.05).Conclusions The color of porcelain-fused-to-titanium restorations was influenced by different framework production techniques.
Physical Activity Interventions for The Management of Hypertension: A Scoping Review
Authors: Simamane Mandisa , Constantinou Demitri , Gradidge Philippe Jean-Luc , Watson Estelle 
Published: April 2023

Abstract

Background For all persons with hypertension, the potential benefits of a healthy diet, weight control, and regular exercise cannot be overemphasized. Patients with hypertension should be encouraged to undertake a light-to-moderate intensity exercise programme without needing to consult with their doctor.Aim The purpose of this scoping review was to gain perspective on the specific interventions that worked for hypertension management to have an overall understanding of which type of exercise, frequency, duration, intensity, and time that has an effect in hypertension management.Method A scoping review was conducted according to the methodologically rigorous scoping review approach proposed by Arksey and O’Malley. A search engine was undertaken from Database A-Z: COCHRANE; EBSCOHost: CINAHL Complete, Global Health, and MEDLINE Complete; ProQuest Health & Medical Complete; PubMed; SA ePublications; ScienceDirect; and SCOPUS.Results There were randomised controlled/ experimental studies (N = 31) which fulfilled the inclusion criteria, with successful interventions (n = 9). Duration ranged from minimum of 8 to a maximum 24 weeks, the interventions had the most consistent frequency of 2–3 days/week. Time varied from 20 to 70 minutes per session, and intensity of > 50% in both aerobic and strength exercises elicit positive physiological changes.Conclusion Aerobic exercise programme alone can have the same results as that of a combined exercise programme, which also takes into consideration other physiological aspect.Contribution: This review provided clarifications on when you can prescribe physical activity programme in any settings and how these can have a positive effect in managing hypertension.
Brain-Computer Interfaces for Children: A Comparative Study of Five Common EEG-based Paradigms
Authors: Kelly Dion , Zewdie Ephrem , Carlson Helen , Kirton Adam 
Published: April 2023

Abstract
Background Quadriplegic cerebral palsy (QCP), the most severe form of cerebral palsy (CP), affects millions of individuals worldwide. Children with QCP often have intact cognitive function but face challenges in communication or interaction with their environments, which may result in a condition similar to "locked-in syndrome." Brain-computer interfaces (BCIs) hold potential to help, but pediatric BCI research has been limited. This study aimed to establish baseline performance of common BCI paradigms in typically developing children to support applications in children with disabilities.Methods Performance on five BCI paradigms, including visual (P300), auditory (AEP), and vibro-tactile (VTP2 and VTP3) event-related potentials, and sensorimotor rhythm (SMR) modulation using motor imagery, was evaluated in thirty school-age children using tasks with predefined goals. Two commercially available EEG-based BCI systems, Mindbeagle® and intendiX®, were used. The primary outcome was online classification accuracy. Potential factors affecting performance, including age, sex, motivation, tolerability, and fatigue, were also explored.Results We found that most children were able to demonstrate competency on multiple BCI paradigms with favorable tolerability and no serious adverse events. Mean accuracy across all paradigms was 77.03%, with 73% achieving BCI competency. Performance on P300-based paradigms was better than the SMR paradigm, with the highest performance observed in the VTP2 paradigm (89.48%), and the lowest in the SMR paradigm (55.68%). Significant differences in accuracy and fatigue were observed across the paradigms, with the visual P300 spelling paradigm showing the highest motivation and lowest fatigue. Age was correlated only with AEP BCI performance, while no other factors appeared to influence performance across paradigms.Conclusion We conclude that evoked potential BCI paradigms are generally effective in children as young as 6 years of age in a laboratory setting for potentially meaningful tasks, such as communication, recreation, and computer operation. The research contributes to the limited knowledge on non-invasive BCI performance in children and offers insights into factors affecting performance. More research is needed to understand how these BCI paradigms can be optimized for children and implemented in real-world environments and as assistive technology for youth with disabilities.
Understanding Camouflaging and Identity in Autistic Children and Adolescents Using Photo-Elicitation
Authors: Howe Stephanie J. , Hull Laura , Sedgewick Felicity , Hannon Benjamin 
Published: April 2023

Abstract

Purpose Camouflaging, or the use of strategies by autistic people to minimize the visibility of their autistic traits in social situations, is associated with stress, autistic burnout, depression, and suicidality among autistic adults. However, little is known about how autistic children and adolescents experience camouflaging, limiting our understanding of its onset and development. The present study filled this knowledge gap by examining camouflaging behaviour among autistic children and adolescents using a photo-elicitation approach.Methods Eight autistic children and adolescents aged 10 to 14 years (M = 11.88, SD = 1.89) attended an orientation session and were given two to three weeks to take photographs on the topic of camouflaging. Individual interviews were conducted with each participant about their photos. Inductive thematic analysis and an interpretive engagement framework were used to identify major themes within participant interviews and images.Results Qualitative analysis identified 12 themes reflecting motivations to camouflage (as a response to negative social experiences, as a learned habit), contexts of camouflaging (e.g., the audience), strategies and behaviours used to camouflage (suppressing autistic stimming behaviour, hiding the self), and perceived consequences of camouflaging (internal conflict, stress, needing time to recharge).Conclusion Results highlight that autistic children and adolescents as young as 10 years old engage in camouflaging behaviour which can be pervasive and automatic, and that this can be a stressful, confusing, and energetically draining experience. Better understanding of the development and experience of camouflaging in childhood can inform prevention of mental health concerns in adulthood.