bluuebunny/crossref_metadata_2025_split huggingface dataset:
The incidence of hyponatremia in hospitalized patients due to hip fracture and its effect on mortality
Authors: KAYAOKAY Kemal , ARSLAN YURTLU Derya 
Published: July 2023

Purpose: Hyponatremia is associated with high morbidity and mortality in elderly patients. This study aimed to investigate the incidence of hyponatremia and its effects on the duration of hospitalization, in-hospital and 1-year mortality in elderly patients admitted to the hospital due to hip fracture.
Materials and Methods: After the approval of the ethics committee, patients over the age 65 and had hip surgery between January-December 2020 were retrospectively analyzed. The age, gender, fracture type, current comorbidities, and American Society of Anesthesiology physical status scores of the patients were recorded. Plasma Na, K, and Ca values in admission to hospital were recorded. Patients with hyponatremia and normonatremia were compared in terms of demographic data, comorbidities, duration of hospitalization, in-hospital, and 1-year mortality rates.
Results: Of the total 253 patients, 52(%20.5) had hyponatremia at hospital admission. Demographic data were similar in hyponatremic and normonatremic patients. In hyponatremia group mean Na values were 131.13±3.96 mmol/L and significantly lower than normonatremia group (138.73±2.27). In the hyponatremic group, diabetes mellitus was observed in 23 (44%) patients, and congestive heart failure was observed in 9 (17%) patients, which was higher than the normonatremic group. The preoperative and total duration of hospitalization was 5.21±2.68 and 9.92±4.49 days respectively and higher in patients with hyponatremia. In-hospital and 1-year mortality rates were similar between the groups.
Conclusion: The incidence of hyponatremia was found to be 20.5% in patients with hip fractures, and both the preoperative and total hospital stays were prolonged in these patients. Although mortality rates were similar in this study, hyponatremia requires careful follow-up and early treatment in these patients, since it is known that the length of hospital stay increases mortality.
The Development Studies on Islamic Economic Education Based on Local Wisdom in Indonesia: A Multicultural Approach
Authors: Fathurrahman Ayif 
Published: July 2023

This article focuses on the development of islamic economic education in Indonesia with multi-cultural approach. It tries to reaffirm the universal values of Islam and to adjust these values to local values that have long been entrenched in the midst of Indonesian multicultural society. This research method is descriptive qualitative research using data sources from literature or library research. The research approach uses a normative approach. The normative approach is used to examine the ideals of the Islamic Economic conception and then analyze how it is applied. The result of this research regarding the urge of developing islamic economic based on multicural perspective: firstly it is because of the emergence of globalization era and postmodern culture. Secondly, the reality of Indonesian plurality, apart as syiar, is used to explore the local genius in socio economic in Indonesia. Then Islamic economic education with multicultural approach is a progressive approach to transform education that holistically provides criticism and shows the weaknesses of Islamic economic education. Islamic economic education based on local values as an instrument of social adjustment encourages the administrators of Islamic economics to be able to play a role in instilling the awareness of the multicultural community to realize a level of comprehension of inclusive Islamic ecnomic.
Research Topic Trends In Information And Communication Technology Indexed Science And Technology Index (Sinta) 1 Year 2021 With The Zipf Approach
Authors: Via  , Nining Sudiar  , Amelia Vita 
Published: July 2023

ABSTRACT
This study aims to find out about the trend topics that are more often discussed in Information & Communication Technology journals indexed by SINTA 1 in 2021 so that they can bring up the latest research subjects. The method used in this research is to use the bibliometric data analysis method based on the zipf rule. The results showed that there was the word "Learning" which was the highest word frequency, which was 317 times appearing with a percentage (3.8%) of the total 8246 words. Then followed by the word "Network" as much as 258 times (3.1%), then "Neural" is a word that appears 235 times or equivalent to (2.8%), the word "System" is also found 160 times, namely with a percentage (1.9%), followed by the word "Machine" 146 times appearing which is equivalent to (1.8%), then the word "Data" also appearing 135 times with a percentage (1.6%), appearing Also the word "Algorithm" is 127 times with a value (1.5%), the word "Image" appears 124 times with a percentage of (1.5%), the word "Energy" is also found 121 times appears with a value (1, 5%) and the top ten words ended with the word “Deep” which appeared 118 times with a percentage (1.4%). These words can be used as keywords in the research article being studied. The calculation above shows that the relevant subject index is greater with the relevant percentage of 62.5%, relevant marginal of 37.5% and irrelevant of 0 %.
Keywords : Zipf rules, Bibliometrics, Journals, Articles, Words: Learning

Tren Topik Penelitian Jurnal Teknologi Informasi Dan Komunikasi Terindeks Science And Technology Index (Sinta) 1 Tahun 2021 Dengan Pedekatan Dalil Zipf
ABSTRAK
Penelitian ini bertujuan untuk mengetahui permasalahan tentang tren topik-topik apa saja yang lebih sering dibahas dalam jurnal Teknologi Informasi dan Komunikasi yang terindeks SINTA 1 pada tahun 2021 sehingga bisa memunculkan subjek penelitian terbaru. Metode yang digunakan pada penelitian ini yaitu menggunakan metode analisis data bibliometrik dengan berdasarkan kaidah zipf. Hasil penelitian ini menunjukkan bahwa terdapat kata “Learning” merupakan frekuensi kata tertinggi yaitu sebanyak 317 kali muncul dengan jumlah persentase (3,8%). Maka dapat diambil kesimpulan bahwa kata tersebut dapat dijadikan sebagai kata kunci (Keyword) pada penelitian artikel yang sedang diteliti. Perhitungan diatas menunjukkan indeks subjek yang nilainya relevan lebih besar dengan jumlah persentase relevan sebesar 62.5%, persentase relevan marginal sebesar 37,5% dan jumlah persentase tidak relevan sebesar 0 %.
Keywords: Kaidah Zipf, Bibliometrik, Jurnal, Artikel, Kata: Learning.
Prognostic value of the levels of CTLA-4 and its ligand B7.2 in patients with colorectal cancer
Authors: Chetveryakov A. V. , Tsepelev V. L. 
Published: July 2023

Aim. To develop a computer program to determine the probability of colorectal cancer based on the assessment of the levels of CTLA-4 and its ligand B7.2.Materials and methods. The study included 44 patients with colorectal cancer (CRC) and 25 patients with benign tumors of the colon. The control group consisted of 25 individuals who had been operated for colon injury. We determined the levels of CTLA-4 and B7.2 in the blood serum and in the supernatants of tumor tissue and lymph node homogenates using flow cytofluorometry.Results. We found that the level of CTLA-4 in the blood serum increased by 2.77 times in CRC patients compared to the control group (p < 0.001). The concentration of CTLA-4 in the tumor tissue in patients with CRC was 2.34 times higher than in the control group (p = 0.007). The concentration of the B7.2 ligand in the blood serum of patients with CRC exceeded this parameter in the control group by 2.51 times (p = 0.002). The concentration of B7.2 in the tumor tissue of CRC patients was 1.68 times higher (p = 0.004) than in the control group. The analysis of the obtained data determined the parameters that have prognostic value in the structure of the diagnostic model. Using these parameters, we developed a computer program to determine the probability of CRC in the patient.Conclusion. The data obtained demonstrate an increase in the levels of CTLA-4 and its ligand B7.2 in the serum and tumor tissue of patients with CRC.
Marketability Study of Mathematical Sciences Students in Universiti Kebangsaan Malaysia (UKM)
Authors: Lim Chui Ting  , Ong Wen Xuan  , Muhammad Aris Fadzilah Nurulain Nabilah Binti , Nora Binti Muda  
Published: July 2023

Higher Education Institute (HEI) has a vital role in developing human capital of a country. Measuring the quality of teaching and learning system in HEI and also industry’s satisfaction level is important to ensure the marketability of HEI graduates. This study examined Universiti Kebangsaan Malaysia (UKM) Mathematical Sciences students’ marketability by determining industry’s satisfaction level on students’ skills and abilities during industrial training and identifies factors that affect students’ marketability. There were 22 student attributes that were categorized into four factors. Mean scores and Relative Importance Analysis determined the satisfaction and importance level of each attribute studied respectively. Besides, Penalty-Reward Contrast Analysis (PRCA) showed that affective factor was categorized as a basic factor where its existence did not increase but its absence decreased the industry’s satisfaction level. For Importance Performance Analysis (IPA), cognitive, affective, and cognitive & psychomotor factors were observed in the first quadrant which had high importance level but low performance level. Lastly, all four factors were found in the loyal customer zone and at an excellent level through Customer Satisfaction Index (CSI) analysis. In conclusion, UKM Mathematical Sciences students have high marketability in general, but preservation and improvement should be implemented on important attributes to enhance their marketability.
Élményalapú nyelvtörténet
Authors: Sarnyai Vivien 
Published: July 2023

2015-ben megalakult az ELTE Alkalmazott Nyelvtörténeti Kutatócsoportja, amely – többek között – a nyelvtörténet közoktatásban betöltött szerepét helyezte a középpontba. Ez a résztéma időközben önálló kutatási területté vált, és megalakult az ELTE Benkő Loránd Nyelvtörténeti Hallgatói Műhely vezetése alatt a Nyelvtörténet az oktatásban elnevezésű kutatócsoport. A kutatás fókuszában a pedagógusok és a diákok nyelvtörténet iránti attitűdje állt. A magyartanárokkal készített interjúk azt igyekeztek feltérképezni, hogy a pedagógusok a nyelvtörténetnek milyen témaköreit érintik, milyen nehézségekbe ütköznek, és hogy az egyetemtől milyen segítséget várnak. Ez utóbbira a leggyakoribb válasz az volt, hogy jelentősen segítené a munkát, ha rendelkezésükre állna egy középiskolásoknak szánt nyelvtörténeti feladatgyűjtemény. A kutatócsoport ennek a kívánalomnak igyekezett eleget tenni, így 2020 tavasza óta több mint 200 feladat készült el, amely hamarosan feladatgyűjteményként fog napvilágot látni.
Modulation of temporal and occipital cortex by acupuncture in non- menstrual MWoA patients: A Rest Bold fMRI study
Authors: Yang Yu-Chan , Wei Xiang-Yu , Zhang Ying-Ying , Xu Chun-Yang , Cheng Jian-Ming , Gong Zhi-Gang , Chen Hui , Huang Yan-Wen , Yuan Jie , Xu Hui-Hui , Wang Hui , Zhan Song-Hua , Tan Wen-Li 
Published: July 2023

Abstract
Objective
To investigate the changes in amplitude of low-frequency fluctuation (ALFF) and degree centrality (DC) values before and after acupuncture in young women with non-menstrual migraine without aura (MWoA) through rest blood-oxygen-level-dependent functional magnetic resonance imaging (BOLD fMRI).
Methods
Patients with non-menstrual MWoA (Group 1, n = 50) and healthy controls (Group 2, n = 50) were recruited. fMRI was performed in Group 1 at 2 time points: before acupuncture (time point 1, TP1); and after the end of all acupuncture sessions (time point 2, TP2), and performed in Group 2 as a one-time scan. Patients in Group 1 were assessed with the Migraine Disability Assessment Questionnaire (MIDAS) and the Short-Form McGill Pain Questionnaire (SF-MPQ) at TP1 and TP2 after fMRI was performed. The ALFF and DC values were compared within Group 1 at two time points and between Group 1 and Group2. The correlation between ALFF and DC values with the statistical differences and the clinical scales scores were analyzed.
Results
Brain activities increased in the left fusiform gyrus and right angular gyrus, left middle occipital gyrus, and bilateral prefrontal cortex and decreased in left inferior parietal lobule in Group 1, which had different ALFF values compared with Group 2 at TP1. The bilateral fusiform gyrus, bilateral inferior temporal gyrus and right middle temporal gyrus increased and right angular gyrus, right superior marginal gyrus, right inferior parietal lobule, right middle occipital gyrus, right superior frontal gyrus, right middle frontal gyrus, right anterior central gyrus, and right supplementary motor area decreased in activity in Group 1 had different DC values compared with Group 2 at TP1. ALFF and DC values of right inferior temporal gyrus, right fusiform gyrus and right middle temporal gyrus were decreased in Group1 at TP1 compared with TP2. ALFF values in the left middle occipital area were positively correlated with the pain degree at TP1 in Group1 (correlation coefficient r, r = 0.827, r = 0.343; P < 0.01, P = 0.015). The DC values of the right inferior temporal area were positively correlated with the pain degree at TP1 in Group 1 (r = 0.371; P = 0.008).
Conclusion
Spontaneous brain activity and network changes in young women with non-menstrual MwoA were altered by acupuncture. The right temporal area may be an important target for acupuncture modulated brain function in young women with non-menstrual MwoA.
Support Vector Data Description with Kernel Density Estimation (SVDD-KDE) Control Chart for Network Intrusion Monitoring
Authors: Ahsan Muhammad , Khusna Hidayatul , Wibawati Wibawati , Lee Muhammad Hisyam 
Published: July 2023

Abstract

Multivariate control charts have been applied in many sectors. One of the sectors that employ this method is network intrusion detection. However, the issue arises when the conventional control chart faces difficulty monitoring the network-traffic data that do not follow a normal distribution as required. Consequently, more false alarms will be found when inspecting network traffic data. To settle this problem, support vector data description (SVDD) is suggested. The control chart based on the SVDD distance can be applied for the non-normal distribution, even the unknown distributions. Kernel density estimation (KDE) is the nonparametric approach that can be applied in estimating the control limit of the non-parametric control charts. Based on these facts, a multivariate chart based on the integrated SVDD and KDE (SVDD-KDE) is proposed to monitor the network's anomaly. Simulation using the synthetic dataset is performed to examine the performance of the SVDD-KDE chart in detecting multivariate data shifts and outliers. Based on the simulation results, the proposed method produces better performance in detecting shifts and higher accuracy in detecting outliers. Further, the proposed method is applied in the intrusion detection system (IDS) to monitor network attacks. The NSL-KDD data is analyzed as the benchmark dataset. A comparison between the SVDD-KDE chart with the other IDS-based-control chart and the machine learning algorithms is executed. The results show that the IDS based on the SVDD-KDE chart produces a high accuracy at 0.917 with a low false positive rate at 0.062 compared to several algorithms.
Unlocking the Antioxidant and Antimicrobial Potential of Flavone and Amide-rich Fractions from Conchocarpus macrocarpus (Rutaceae) Leaves
Authors: Silveira Elielson Rodrigo , Torres Priscila Bezerra , Scortecci Katia Castanho , Rocha Hugo Alexandre Oliveira , Suffredini Ivana Barbosa , Silva Jefferson de Souza , Santos Déborah Yara Alves Cursino dos 
Published: July 2023

Abstract
Conchocarpus macrocarpus (Rutaceae) is an endemic species in Brazil, whose chemical and biological properties are poorly understood. This study aimed to evaluate the antioxidant and antimicrobial potential of the butanolic partition phase extracted from C. macrocarpus leaves collected in Espírito Santo, Brazil. In vitro antioxidant assays, including DPPH radical scavenging and Folin-Ciocalteu assay, and cytotoxicity and antioxidant activity in RAW cells using the MTT method were performed. Additionally, antimicrobial activity against Staphylococcus aureus, Escherichia coli, and Candida albicans was investigated. Results showed that the flavone-rich fraction exhibited the strongest antioxidant activity, as observed for the PF-BuOH G2.1 fraction that showed values of 237.2 ± 1.4 mg TE/g of extract and 118.2 ± 1.6 mg GAE/g of extract. However, the samples did not show protective effects against hydrogen peroxide. Furthermore, the flavones and amides present in the PF-BuOH G2.1 fraction displayed antimicrobial activity against C. albicans, showing a minimum inhibitory concentration of 1.25 mg/mL at the highest microbial load (1.5x105 CFU/mL). Our findings provide insights into the chemical composition and biological potential of C. macrocarpus and highlight the promising applications of the BuOH partition phase and its fractions.
Vehicle License Plate Recognition Algorithm Based on Deep Learning
Authors: Li Qiaojun 
Published: July 2023

Abstract
With the gradual increase of car ownership in China, license plate recognition plays an important role in intelligent vehicle management system. The existing vehicle number recognition algorithms have slow recognition speed and low accuracy, and are easy to be affected by the light, the position angle of the license plate and the relative fixed position of the camera. The Faster-RCNN based on deep learning locates the license plate, generates the license plate extraction frame and extracts the license plate; Use VGGnet network model to recognize characters, and finally complete the recognition of car license plate. Training and testing are carried out in a large number of data sets. The simulation results show that the network model combining fast RCNN and VGGnet can recognize the license plate with an accuracy of 99.2% in a complex environment, and the recognition accuracy is better than other algorithms.
Correlation of preoperative hematological markers with clinicopathological features of LSCC
Authors: Qi Hui , Han Shifan 
Published: July 2023

Abstract
Objective
This study aimed to examine the relationship between hematological markers and the detection and diagnosis of LSCC, the development of carcinoma, and their clinical importance.
Methods
Patients with LSCC were searched through the laryngeal cancer-specific database. Clinical data such as sex, age, clinical classification, T-stage, N-stage, pathological stage, smoking and drinking habits, blood routine, biochemical examination, and coagulation examination were collected, and all data were processed by SPSS 23.0 statistical software, and P < 0.05 was considered a statistically significant difference.
Results
Clinical classification and pathological stage were correlated with NLR, PLR, and LMR levels (P < 0.05). There was a correlation between the T stage and NLR levels (P < 0.05). There was a correlation between smoking and LMR level (P < 0.05). PLT levels were linked with age, T stage, N stage, and alcohol consumption (P < 0.05). T stage and N stage were connected with PDW levels (P < 0.05). Sex, clinical classification, and HB levels were associated (P < 0.05). Age, clinical classification, and N stage were connected with ALB level (P < 0.05). Age, clinical classification, pathological stage, T stage, N stage, and alcohol consumption were connected with PA level (P < 0.05). There was a correlation between sex and APTT level (P < 0.05). Clinical classification, T stage, and FIB level were associated (P < 0.05).
Conclusion
Increased levels of NLR, PLR, PLT, and FIB and decreased levels of LMR, MPV, PDW, HB, ALB, and PA are associated with poor clinicopathological features of LSCC. Hematological markers are important in monitoring cancer progression, guiding treatment, and predicting prognosis.
Role of FoxO1 in pulmonary artery endothelial autophagic function in chronic thromboembolic pulmonary hypertension rats
Authors: Wu Dawen , Wu Shuang , Yang Minxia , Li Hongli , Wang Wenfeng , Chen Yunfei , Deng Chaosheng 
Published: July 2023

Abstract
Aims
To detect the effect of forkhead box transcription factor O-1 (FoxO1) on autophagy of pulmonary artery in chronic thromboembolic pulmonary hypertension (CTEPH) rats.
Methods
Rats were divided into sham group and three experimental groups. In the experimental group, autologous blood clots were injected into the right jugular vein of rats to induce the CTEPH animal model. The experimental group was randomly divided into three groups, thrombosis group (n = 24), FoxO1 agonist treatment group (resveratrol) (n = 24) and FoxO1 inhibitor treatment group (AS1842856) group (n = 24). The mean pulmonary arterial pressure (mPAP), the area of pulmonary artery wall/total area (WA/TA) and the expression levels of FoxO1, pFoxO1, LC3 and Beclin1 in pulmonary artery were measured.
Results
The mPAP and WA/TA ratio in the FoxO1 agonist group were decreased significantly (P < 0.05). The mPAP and WA/TA ratio in the FoxO1 inhibitor were increased significantly (P < 0.05). The mPAP was negatively correlated with pFoxO1 in experimental group (r=-0.967, P < 0.001), the expression of pFoxO1 protein was positively correlated with FoxO1 protein expression (r = 0.972, P < 0.001), expression of LC3 protein was positively correlated with the expression of pFoxO1 protein (r = 0.871, P < 0.001), Beclin1 protein expression was positively correlated with pFoxO1 protein expression (r = 0.953, P < 0.001).
Conclusion
There is a decreased autophagy activity and FoxO1 expression of pulmonary artery in CTEPH rats. FoxO1 may be involved in pulmonary artery remodeling process and contribute to the development of CTEPH by regulating autophagy activity, but the concrete mechanism are unknown.
No genetic evidence for the association between COQ7 and Chinese patients with Amyotrophic Lateral Sclerosis
Authors: Yu Weiyi , He Ji , Zheng Wei , Liu Xiaoxuan , Fan Dongsheng 
Published: July 2023

Abstract

Background Amyotrophic lateral sclerosis (ALS) is a devastating progressive neurodegenerative disease. Recently, homozygous and compound heterozygous pathogenic variants in theCOQ7gene were identified in patients with Hereditary Spastic Paraplegia (HSP), and distal hereditary motor neuropathy (dHMN). Inspired by the pathological, clinical and genetic overlap of these diseases with ALS, the association betweenCOQ7and the pathogenesis of ALS was studied. Results 3 heterozygous nonsynonymous variants in 3 sporadic ALS (sALS) patients, 0 nonsynonymous variants in familial ALS (fALS) patients, 1 heterozygous missense variant in both the ALS cohort and the control cohort, and 10 heterozygous nonsynonymous variants in the control subjects were identified. No homozygous or compound heterozygous pathogenic mutations were found in patients with ALS. The frequency of rare or likely pathogenic variants was not statistically different between the ALS cohort and the control cohort. Conclusions Our results did not find an association betweenCOQ7and ALS in Chinese patients, and further study may be required.