bluuebunny/crossref_metadata_2025_split huggingface dataset:
Atomic-scale insights into topotactic transformations in an extra-large-pore zeolite using time-resolved 3D electron diffraction
Authors: Luo Yi , Xu Hao , Han Yue , Tong Wen , Jiao Meichen , Wang Naihong , Jiang Jingang , Hu Wende , Wang Chuanming , Zou Xiaodong , Wu Peng 
Published: January 2025

AbstractUnderstanding the atomic-scale structural dynamics of phase transformations is crucial for developing materials and tailoring their properties. However, many materials are obtained as polycrystalline powders with large unit cells and/or complex structures, making it challenging to investigate detailed structural changes using conventional X-ray diffraction techniques. Here we employ time-resolved three-dimensional electron diffraction to reveal the topotactic reactions and transformations that convert the extra-large-pore silicate zeolite ECNU-45 into ECNU-46. ECNU-45 features three-dimensional interconnecting 24 × 10 × 10-ring channels, while ECNU-46 consists of one-dimensional 24-ring channels connected to 10-ring pockets. ECNU-45 and ECNU-46 are both examples of pure silicate zeolites with pore openings larger than 22-ring. Our findings indicate changes at six distinct tetrahedral silicon sites, involving atom displacement, addition and removal of framework atoms through bond breakage and formation. This work presents the synthesis of zeolites and also provides atomic-level insights into the dynamic processes of topotactic reactions. Our results have implications for advancing materials engineering and understanding complex solid-state reactions at an atomic scale.
The wide binary frequency of metal-poor stars
Authors: Lodieu N. , Pérez Garrido A. , Zhang J.-Y. , Martín E. L. , Rebolo López R. , Pérez-Toledo F. , Clavero R. , Nespral D. 
Published: January 2025

Context. This study is aimed at identifying possible low-mass and sub-stellar companions to stars with well-determined metallicities. We investigate the multiplicity of metal-poor stars along with its impact on formation processes in the conditions of the early universe.
Aims. Our goal is to look for wide common proper motion companions to metal-poor stars and study the binarity frequency at low metallicity with astrometry from large-scale catalogues, including Gaia, Visible and Infrared Survey Telescope for Astronomy (VISTA) Hemisphere Survey (VHS), and Wide Field Infrared Survey Explorer (WISE).
Methods. We used the stellar parameter determination from the latest release of the Gaia catalogue to identify metal-poor stars over the entire sky. We combined the Gaia sample with other public catalogues and spectroscopic determinations for a given sub-sample to refine the stellar metallicities. We also considered, as input, other public catalogues of metal-poor stars to look for co-moving companions. We also obtained our own high-resolution images of a sub-sample with the lucky imaging technique.
Results. We only found a few bona fide co-moving systems among a sample of 610 metal-poor stars with metallicities below −1.5 dex in the full sky. We inferred a multiplicity rate below 3%, with 3σ completeness for projected separations larger than 8 au, after taking into account incompleteness and any other limiting factors of our search. At closer separations, we found a minimum binary fraction of 20% that appears to be relatively independent of metallicity.
Conclusions. We conclude that the multiplicity fraction of solar-type stars is relatively independent of metallicity for close-in companions with projected separations below ∼8 au. At separations between 8 and 10 000 au, the binary fraction of metal-poor stars drops significantly to a few percent and is significantly lower than the multiplicity derived for the solar-metallicity case. We interpret these similarities and differences as being due to the chemistry at work in molecular clouds as well as disruption effects attributed to the old age of sub-dwarfs.
Dynamics of the β Pictoris planetary system and possibility of an additional planet
Authors: Lacquement A. , Beust H. , Faramaz-Gorka V. , Duchêne G. 
Published: January 2025

Context. The β Pictoris system is a well-known young planetary system, extensively studied for more than 40 years. It is characterized by a dusty debris disk, in addition to the presence of two already known planets. This makes it a particularly interesting case for studying the formation and evolution of planetary systems at a stage where giant planets have already formed, most of the protoplanetary gas has dissipated, and terrestrial planets could emerge.
Aims. Our goal here is to explore the possibility of additional planets orbiting beyond the outermost known one, β Pictoris b. More specifically, we aim to assess whether additional planets in the system could explain the discrepancy between the predicted cutoff of the disk inner cavity at ~28 au with only two planets, and the observed one at ~50 au.
Methods. We performed an exhaustive dynamical modeling of the debris disk and the carving of its inner edge, by introducing one or two additional planets beyond β Pictoris b, coplanar with the disk. Guided by theoretical predictions for the parameter space – mass, semi-major axis, eccentricity – allowed for additional planets, we further carried out a set of N-body simulations, using the symplectic integrator RMVS3.
Results. Our simulations indicate that an additional planet with a low eccentricity of 0.05, a mass between 0.15 and 1 MJup, and a semi-major axis between 30 and 36 au would be consistent with the observations of an inner debris disk edge at 50 au. We also explored the hypotheses of a higher eccentricity and the presence of two additional lower-mass planets instead of one, which could also account for these observations.
Conclusions. While we find that one or even two additional planets could explain the observed location of the disk inner edge, these hypothetical planets remain in most cases below the current observational limits of high-contrast imaging. Future observational campaigns with improved sensitivity will help to lower these limits and perhaps detect that planet.
Prophylactic Fresh Frozen Plasma Administration: Failure to Reduce Blood Loss or Transfusion Requirements after Routine Cardiopulmonary Bypass
Authors: Snow Norman , Lucas Aaron E. 
Published: January 2025

Cardiopulmonary bypass may result in a variety of coagulation disorders, some of which result in overt hemorrhage. The routine use of blood products to normalize clotting factors in the postbypass period is expensive and may subject the patient to the risk of hepatitis and isoimmunization. We studied the effects of routine administration of four units of fresh frozen plasma (FFP) on standard clotting factors, mediastinal blood loss, and transfusion requirements in a randomized prospective fashion. Twenty-seven patients received plasma and 26 did not. There were no differences in the preoperative clotting studies, blood counts, liver functions, pump time, cross clamp time or type of surgery between the groups.
No differences were noted between the two groups in homologous blood requirements, clotting parameters or mediastinal blood loss. Patients receiving FFP had slightly lower hematocrits in the early postoperative period.
The routine use of FFP had no discernibleeffect on post-bypass hemorrhage or blood usage in a series of open heart operations, most of which were coronary revascularization. The clotting factors in the single reoperated patient were normal. Technical factors and precise heparin reversal play a more important role in postoperative hemostasis than plasma. We cannot recommend the routine administration of FFP after cardiopulmonary bypass.
Neutrophil Extracellular Traps (NETs) as a Potential Target for
Anti-Aging: Role of Therapeutic Apheresis
Authors: Jarzebska Natalia , Rodionov Roman N. , Voit-Bak Karin , Straube Richard , Mücke Anna , Tselmin Sergey , Rettig Ronny , Julius Ulrich , Siow Richard , Gräßler Jürgen , Passauer Jens , Kok Yannick , Mavberg Philip , Weiss Norbert , Bornstein Stefan R. , Aswani Andrew 
Published: January 2025

AbstractNeutrophil extracellular traps (NETs) are large structures composed of chromatin,
histones and granule-derived proteins released extracellularly by neutrophils.
They are generally considered to be a part of the antimicrobial defense
strategy, preventing the dissemination of pathogens. However, overproduction of
NETs or their ineffective clearance can drive various pathologies, many of which
are associated with advanced age and involve uncontrolled inflammation,
oxidative, cardiovascular and neurodegenerative stress as underlying mechanisms.
Targeting NETs in the elderly as an anti-aging therapy seems to be a very
attractive therapeutic approach. Therapeutic apheresis with a specific filter to
remove NETs could be a promising strategy worth considering.
Correlation between Left Ventricular Mass and Cardiac Troponin T in Cardiac Surgery
Authors: Leviner Dror B. , Touitou Ayelet R. , Adawi Salim , Sharoni Erez 
Published: January 2025

AbstractCardiac troponin levels might rise significantly after cardiac surgeries as a surgical outcome rather than ischemic myocardial damage alone, making the diagnosis of postoperative (type 5) myocardial infarction challenging. Previous studies have demonstrated that cardiac troponin is related to left ventricular mass, but this correlation was not investigated after cardiac surgery. We aimed to study a possible correlation between postoperative cardiac troponin levels and left ventricular mass index in patients who underwent cardiac surgery to refine the diagnosis of type 5 myocardial infarction, but observed no such correlation regardless of preoperative troponin levels or surgery type.
Frühe Erfassung von zukünftigen Pandemieeffekten bei Menschen mit
schweren psychischen Erkrankungen: Können laufende bevölkerungsrepräsentative
Kohortenstudien einen Beitrag leisten?
Authors: Wittmann Felix G. , Luppa Melanie , Höhn Anna , Wege Natalia , Ascone Leonie , Lohse Luzie , Hurlemann René , Meisenzahl Eva , Lambert Martin , Bajbouj Malek , von Lilienfeld-Toal Marie , Riedel-Heller Steffi G. 
Published: January 2025

ZusammenfassungDiese Übersicht geht der Frage nach, ob laufende
bevölkerungsrepäsentative Kohorten zukünftige Pandemieeffekte auf Menschen mit
schweren psychischen Erkrankungen detektieren können.Literaturrecherche mit anschließender Analyse und Evaluation
bezüglich relevanter Messungen und Kriterien.Keine der laufenden deutschen bevölkerungsbasierten Kohortenstudien
inkludieren Personen mit schweren psychischen Störungen nach den gängigen
diagnostischen Kriterien. Vier Kohorten umfassen Menschen mit schwerer
Depressivität und Ängstlichkeit.Bevölkerungsrepräsentative Kohorten leisten keinen
nennenswerten Beitrag zur schnellen Erfassung von zukünftigen Pandemieeffekten
im Hinblick auf Menschen mit schweren psychischen Erkrankungen.
Patientenkohorten erschienen geeigneter, um Erkenntnisse zum Schutz dieser
vulnerablen Gruppe unter Pandemiebedingungen zu generieren. Diese gilt es
aufzubauen und zu pflegen.
Outcomes and Complications of Chait Trapdoor Cecostomy in Pediatric Patients with Therapy-Resistant Constipation and Fecal Incontinence: A 14-Year Retrospective Study
Authors: Jonker Charlotte Anne Louise , Koppen Ilan , Benninga Marc A. , Jong Justin R. de , Gorter Ramon 
Published: January 2025

Abstract
Aim of the Study To assess the incidence and types of complications and patient-reported outcomes in pediatric patients with therapy-resistant constipation or fecal incontinence (FI) without constipation who underwent Chait Trapdoor™ cecostomy (CTC). The findings contribute to the discussion on selecting the optimal antegrade continence (ACE) procedure for this population.
Materials and Methods A retrospective review was conducted on all pediatric patients with therapy-resistant constipation or FI without constipation who underwent a CTC procedure at our tertiary referral center between 2009 and 2023. Postoperative complications were classified using the Clavien-Madadi classification. At their most recent follow-up in 2023, patients reported satisfaction with their CTC.
Results The study included 62 children (median age 12 years [IQR 8–14; range 1–17], 42% male), with a median follow-up of 4 years (IQR 2–8, range 0–14). Underlying diagnoses were functional constipation (n = 39, 63%), spina bifida (n = 11, 18%), and anorectal malformations (n = 5, 8%). A total of 49/62 patients (79%) experienced 89 CTC-related complications. Minor complications (Clavien-Madadi I–II) affected 29 patients (47%) and most commonly included granulation. Major complications (Clavien-Madadi III–IV) requiring surgery occurred in 32% of patients. Despite these complications, 40/62 (65%) patients reported satisfaction with their CTC, as determined by partial or complete symptom resolution.
Conclusions Although complications were common, 65% of the patients reported satisfaction with their CTC. These findings emphasize the need for thorough patient selection, informed counseling on potential risks, and individualized management strategies to enhance outcomes.
Nickel-Catalyzed Cross-Electrophile [2+4] Annulation of Benzynes
Authors: Wang Chuan , Dong Haiyan , Ding Xinrang 
Published: January 2025

AbstractCross-electrophile coupling (XEC) reactions have emerged as powerful tools for C–C bond formation, whereas annulation employing arynes provides unique approaches to polycyclic arenes. Herein, we report a nickel-catalyzed cross-electrophile [2+4] annulation using benzynes and a 1-bromo-2-(2-chlorovinyl)arenes as C-2 and C-4 synthons, respectively. This proof-of-concept study not only provides a new method for synthesizing polysubstituted phenanthrenes, but also substantiates the feasibility of merging XEC reaction and aryne chemistry.
Challenges and perspectives with understanding the concept of mental
fatigue
Authors: Oliver Liam , Goodman Stephen , Sullivan John , Peake Jonathan , Kelly Vincent 
Published: January 2025

AbstractMental fatigue is referred to as a psychophysiological or neurobiological state
caused by prolonged periods of demanding cognitive activity. Sport and exercise
science research studies have investigated the effects of experimentally induced
mental fatigue on cognitive performance, with mixed results. It has been
suggested that negative effects of mental fatigue on cognition performance in
laboratory studies could translate to impaired sport performance. However, it
remains unclear if impairments in sport performance are due to mental fatigue
and how mental fatigue may differ from physical fatigue. Fatigue is well
understood as a complex multifactorial construct involving interactions between
physiological and neuropsychological responses across brain regions. It may be
prudent for researchers to return to the origins of fatigue and cognition before
attempting to connect mental fatigue and sport cognition. This article reviews
the concept of mental fatigue, its mechanisms and neuroanatomical basis, models
of cognition relevant to sports science, investigates how mental fatigue may
influence cognition, and suggests future research directions. Mental fatigue as
a construct separated from fatigue could be an oversight that has hindered the
development of our understanding of mental fatigue. Future sports science
research could work to enhance our knowledge of our definitions of fatigue.
Transoral Drug-Induced Sleep Endoscopy: A Useful Complementary Tool in Sleep Surgery
Authors: Elsobki Ahmed , Elshaer Mohammed , Ghabn Hassan , El-deeb Mohamed E. , Suliman Luci 
Published: January 2025

Abstract
Introduction Drug-induced sleep endoscopy (DISE) is performed widely, and several studies have demonstrated its validity as it provides clinical information not available by routine clinical inspection alone.
Objective This study aims to evaluate the role of transoral drug-induced sleep endoscopy (DISE) in the evaluation of tongue-palate (TP) interaction and its impact on surgical outcomes.
Methods A total of 42 patients with known obstructive sleep apnea syndrome (OSAS) were classified into two groups according to TP interaction (the absence of space between tongue and palate with the visual impression that the tongue is pushing the soft palate) into +ve and –ve TP interaction. Snoring according to the visual analogue scale (VAS), the Epworth Sleepiness Scale (ESS), and sleep study data were recorded before and after the pharyngoplasty operation.
Results There was a statistically significant difference between studied groups postoperative regarding minimal oxygen saturation, snoring index, apnea-hypopnea index (AHI), the ESS, and visual analogue scale of snoring (p = 0.003*, p < 0.001*, p < 0.001*, p = 0.004*, and p = 0.003*, respectively). It displayed a marked higher average improvement among cases with –ve than in those with +ve TP interaction in terms of snoring index, AHI, and ESS.
Conclusion The Transoral DISE Has A Valuable Role In Evaluating And Assessing TP Interaction And Its Importance On Surgical Outcomes. Cases With Positive TP Interaction Show Poor Response To Isolated Palatopharyngeal Expansion And Need Further Analysis To Create A Better Treatment Plan And Improve Outcomes.
Incidence, Risk Factors and Outcomes of Urinary Tract Infections among Patients Undergoing Thyroidectomy: Insights from the ACS-NSQIP
Authors: Waqar Usama , Ahmed Warda , Fazal Zoha Zahid , Chaudhry Ahmad Areeb , Iftikhar Haissan , Ziauddin Afsheen , Abbas Syed Akbar 
Published: January 2025

Abstract
Introduction Urinary tract infections (UTIs) represent a rare postoperative complication following thyroidectomy.
Objective This study aimed to assess the clinicodemographic factors associated with the development of UTIs and subsequent outcomes among patients undergoing thyroidectomy.
Methods This retrospective study used the National Surgical Quality Improvement Program (NSQIP) database to analyze patients who underwent thyroidectomy from 2005 to 2019. Multivariable logistic regression models were used to identify risk factors and associations of UTIs with postoperative morbidity and mortality.
Results In a cohort of 180,373 identified thyroidectomy patients, 0.28% contracted a UTI. Significant risk factors associated with UTIs included age > 60 years (adjusted odds ratio [OR] 2.187, 95% confidence interval [CI] 1.618–2.956), female gender (OR 1.767, 95% CI 1.372–2.278), American Society of Anesthesiologists (ASA) Classification 3 to 5 (OR 1.463, 95% CI 1.185–1.805), partially (OR 4.267, 95% CI 2.510–7.253) or totally dependent functional health status (OR 9.658, 95% CI 4.170–22.370), pulmonary disease (OR1.907, 95% CI 1.295–2.808), chronic steroid therapy (OR 1.649, 95% CI 1.076–2.527), inpatient procedure (OR 1.507, 95% CI 1.251–1.814), and operative time > 150 minutes (OR 1.449, 95% CI 1.027–2.044). Additionally, UTIs were independently associated with postoperative complications, including pulmonary, vascular, or cardiac complication; stroke; acute renal failure; infectious complications; sepsis; septic shock; pneumonia; prolonged length of stay; unplanned reoperation; and mortality.
Conclusion While UTIs are rare after thyroidectomy, they carry a significant burden on patient outcomes. Preoperative optimization of comorbidities and reducing operative times may help mitigate the risk of UTIs. Optimized care for postoperative UTI patients is also recommended to prevent complications and improve outcomes.
Postoperative Hearing Outcomes and Usefulness of Endoscopy-Assisted Tympanoplasty in Pars Tensa Cholesteatoma
Authors: Kurioka Takaomi , Mizutari Kunio 
Published: January 2025

Abstract
Introduction In recent years, transcanal endoscopic ear surgery (TEES) has gained widespread recognition as an excellent surgical field for blind spots such as the sinus tympani (ST) when compared to microscopic ear surgery (MES).
Objective To investigate the postoperative hearing results for pars tensa cholesteatoma and the indications for utilizing endoscopy.
Methods The medical records of 16 patients (10 men and 6 women) with pars tensa cholesteatoma, who received initial surgical treatment between 2018 and 2022, were reviewed. We performed MES, TEES, or endoscopy-assisted MES (dual approach) depending on the pathological involvement in the mastoid cavity and ST.
Results The mean age of the patients was 45 years, and the surgical techniques utilized were MES in 2 cases, TEES in 7 cases, and dual approach in 7 cases. The preoperative pathological classification was stage I in 3 patients and stage II in 13 patients. The overall surgical success rates of postoperative hearing outcomes were 69% and 50% (1/2 patients) in the TEES group, 71% (5/7 patients) in the MES group, and 71% (5/7 patients) in the dual approach group. The successful cases (n = 11) were significantly younger and demonstrated better mastoid pneumatization than unsuccessful cases (n = 5).
Conclusion Endoscopy-assisted MES is appropriate for treating pars tensa cholesteatoma when pathological involvement is present at the deep bottom of the ST. Early surgical intervention and good eustachian tube function are crucial for improving hearing prognosis. Transcanal endoscopic ear surgery can be particularly useful in identifying and removing residual cholesteatoma within the ST.
Identification of Potential High-Risk Patients on the Basis of PROMs in a Certified Centre for Joint Replacement (EndoProthetikZentrum) Using the Example of Hip Arthroplasty
Authors: Osmanski-Zenk Katrin , Klinder Annett , Ellenrieder Martin , Darowski Martin , Goosmann Martin , Mittelmeier Wolfram 
Published: January 2025

Abstract
Background In addition to clinical parameters, the subjective assessment by the patient to evaluate the operative outcome of an arthroplasty is becoming increasingly important. Questionnaires are used to identify patients who have not achieved the treatment goal at an early stage so that further interventions can be indicated.
Material and Methods A questionnaire consisting of different PROMs was completed pre- and 3 months postoperatively by patients who had been treated with a hip arthroplasty. A standardised follow-up examination of these patients was carried out 12 to 16 weeks postoperatively, after which it was determined whether further therapy was necessary to achieve the treatment goal. Different consequences were defined for this.
Results Significant differences were found between the groups of consequences of follow-up examinations over both time points, but also when postoperative scores were considered exclusively. Furthermore, the correlations for the postoperative scores and some consequences of the clinical follow-up for the Oxford Hip Score (OHS), the OHS functional score and the Euroquol-5D show moderate effects. Thus, the collection of these postoperative scores is sufficient to identify potential high risk patients. Based on a receiver operating characteristic (ROC) analysis, threshold values could be determined for these scores, for which a follow-up examination is recommended.
Conclusion Patients who could not achieve functional improvement, pain reduction and improvement in quality of life after implantation of a total hip replacement must be identified at an early stage. The results of our study show that with the help of the Oxford Hip Score and Euroquol-5D, which are answered by the patients three months postoperatively, such high risk patients can be identified. This finding is an added value for the further development of the EndoCert certification system and holistic quality assurance in arthroplasties, while the personnel and time effort remain manageable.