bluuebunny/crossref_metadata_2025_split huggingface dataset:
Use of scientific journals in Spanish universities: analysis of the relationship between citations and downloads in two university library consortia
Authors: Fernández-Ramos Andrés , Rodríguez-Bravo Blanca , Diez-Diez Ángela 
Published: March 2023

AbstractWe analyse the relationship between downloads of electronic journals included in four big deal bundles subscribed to by public university libraries affiliated to two library consortia in Spain (Castile and León and Galicia) and citations of the same journals by researchers at these universities. Download data on the big deals analysed (Emerald, ScienceDirect, Springer and Wiley) were obtained from COUNTER Journal Reports 1, and citation data were obtained from the bibliographic references given in articles indexed in Scopus between 2010 and 2017. The results show that only a low percentage of the subscribed journals was used in the scientific output of the universities’ researchers, with values ranging from 15 to 50%, and that there was a strong correlation between the universities’ volume of scientific production and the percentage of cited journals. We also found a strong correlation between downloads and citations, which was higher in the case of universities with a higher scientific output.
The dubious origin of beryllium toxicity
Authors: Elguero José , Alkorta Ibon 
Published: March 2023

AbstractFour mechanisms have been proposed in the literature to explain beryllium toxicity; they can be divided in two groups of two mechanisms: (i) replacement type: models 1 and 2; (ii) addition type: models 3 and 4. At this moment is not possible to select the best model not even to establish if one of these models will be the ultimate mechanism of beryllium toxicity. However, it is important to know the still open discussion about something so important associated with one of the simplest elements of the periodic table.
Results of a systematic review and meta-analysis of early studies on ivermectin in SARS-CoV-2 infection
Authors: Ragó Zsuzsanna , Tóth Barbara , Szalenko-Tőkés Ágnes , Bella Zsolt , Dembrovszky Fanni , Farkas Nelli , Kiss Szabolcs , Hegyi Péter , Matuz Mária , Tóth Noémi , Hegedüs Imre , Máthé Domokos , Csupor Dezső 
Published: March 2023

AbstractIvermectin, an antiparasitic drug, has been repurposed for COVID-19 treatment during the SARS-CoV-2 pandemic. Although its antiviral efficacy was confirmed early in vitro and in preclinical studies, its clinical efficacy remained ambiguous. Our purpose was to assess the efficacy of ivermectin in terms of time to viral clearance based on the meta-analysis of available clinical trials at the closing date of the data search period, one year after the start of the pandemic. This meta-analysis was reported by following the PRISMA guidelines and by using the PICO format for formulating the question. The study protocol was registered on PROSPERO. Embase, MEDLINE (via PubMed), Cochrane Central Register of Controlled Trials (CENTRAL), bioRvix, and medRvix were searched for human studies of patients receiving ivermectin therapy with control groups. No language or publication status restrictions were applied. The search ended on 1/31/2021 exactly one year after WHO declared the public health emergency on novel coronavirus. The meta-analysis of three trials involving 382 patients revealed that the mean time to viral clearance was 5.74 days shorter in case of ivermectin treatment compared to the control groups [WMD = −5.74, 95% CI (−11.1, −0.39), p = 0.036]. Ivermectin has significantly reduced the time to viral clearance in mild to moderate COVID-19 diseases compared to control groups. However, more eligible studies are needed for analysis to increase the quality of evidence of ivermectin use in COVID-19.
Rate of the phase transition for a charged anti-de Sitter black hole
Authors: Xu Zhen-Ming , Wu Bin , Yang Wen-Li 
Published: March 2023

AbstractPhase transition is a core content of black hole thermodynamics. This study adopted the Kramer’s escape rate method for describing the Brownian motion of particles in an external field to investigate the intensity of the phase transition between small and large black hole states. Some existing studies mostly focused on the formal analysis of the thermodynamic phase transition of black holes, but they neglected the detailed description of the phase transition process. Our results show that the phase transition between small and large black holes for charged anti-de Sitter (AdS) black holes presents serious asymmetric features, and the overall process is dominated by the transition from a small black hole to a large black hole. This study filled a research gap of a stochastic process analysis on the issue of the first-order phase transition rate in the AdS black hole.
Diagnostic posture control system for seated-style echocardiography robot
Authors: Shida Yuuki , Sugawara Masami , Tsumura Ryosuke , Chiba Haruaki , Uejima Tokuhisa , Iwata Hiroyasu 
Published: March 2023

Abstract
Purpose
Conventional robotic ultrasound systems were utilized with patients in supine positions. Meanwhile, the limitation of the systems is that it is difficult to evacuate the patients in case of emergency (e.g., patient discomfort and system failure) because the patients are restricted between the robot system and bed. Therefore, we validated a feasibility study of seated-style echocardiography using a robot.

Method
Preliminary experiments were conducted to verify the following two points: (1) diagnostic image quality due to the sitting posture angle and (2) physical load due to the sitting posture angle. For reducing the physical burden, two unique mechanisms were incorporated into the system: (1) a leg pendulum base mechanism to reduce the load on the legs when the lateral bending angle increases, and (2) a roll angle division by a lumbar lateral bending and thoracic rotation mechanisms.

Results
Preliminary results demonstrated that adjusting the diagnostic posture angle allowed to obtain the views, including cardiac disease features, as in the conventional examination. The results also demonstrated that the body load reduction mechanism incorporated in the results could reduce the physical load in the seated echocardiography. Furthermore, this system was shown to provide greater safety and shorter evacuation times than conventional systems.

Conclusion
These results indicate that diagnostic echocardiographic images can be obtained by seated-style echocardiography. It was also suggested that the proposed system can reduce the physical load and guarantee a sense of safety and emergency evacuation. These results demonstrated the possibility of the usage of the seated-style echocardiography robot.
Who is at Risk of Parkinson Disease? Refining the Preclinical Phase of GBA1 and LRRK2 Variant Carriers: a Clinical, Biochemical, and Imaging Approach
Authors: Menozzi Elisa , Schapira Anthony H. V. , Blandini Fabio , Avenali Micol 
Published: March 2023

Abstract
Purpose of Review
Genetic variants in GBA1 and LRRK2 genes are the commonest genetic risk factor for Parkinson disease (PD); however, the preclinical profile of GBA1 and LRRK2 variant carriers who will develop PD is unclear. This review aims to highlight the more sensitive markers that can stratify PD risk in non-manifesting GBA1 and LRRK2 variant carriers.

Recent Findings
Several case–control and a few longitudinal studies evaluated clinical, biochemical, and neuroimaging markers within cohorts of non-manifesting carriers of GBA1 and LRRK2 variants.

Summary
Despite similar levels of penetrance of PD in GBA1 and LRRK2 variant carriers (10–30%), these individuals have distinct preclinical profiles. GBA1 variant carriers at higher risk of PD can present with prodromal symptoms suggestive of PD (hyposmia), display increased α-synuclein levels in peripheral blood mononuclear cells, and show dopamine transporter abnormalities. LRRK2 variant carriers at higher risk of PD might show subtle motor abnormalities, but no prodromal symptoms, higher exposure to some environmental factors (non-steroid anti-inflammatory drugs), and peripheral inflammatory profile. This information will help clinicians tailor appropriate screening tests and counseling and facilitate researchers in the development of predictive markers, disease-modifying treatments, and selection of healthy individuals who might benefit from preventive interventions.
Implementation and verification of a real-time system for automatic aftershock forecasting in China
Authors: Liu Zhumei , Jiang Haikun , Li Shengle , Li Mingxiao , Liu Jian , Zhang Jingfa 
Published: March 2023

AbstractIn this paper, an automatic aftershock forecasting system for China is presented. Based on a parameter-free historical analogy method, this system can produce short-term aftershock forecast, including seismic sequence types and the magnitude of the largest aftershock, within a few minutes after a major earthquake and can further provide scientists and government agencies with a set of background information for consultation purposes. First, the system construction concept and operation framework are described, and an evaluation of the forecast performance of the system is then conducted considering earthquakes from 2019 to 2021 in mainland China. The results indicate that the sequence type classification precision reaches 83.5%, and the magnitude of more than 90% of the aftershocks is smaller than that of upper range forecast. This system is fast and easy to control, and all the reports and maps can be produced approximately 5 min after earthquake occurrence. Practical use verifies that the application of this system has greatly improved the efficiency of post-earthquake consultation in mainland China.
The role of male partners in modern contraceptive use by women in South Africa: Does space also matter?
Authors: Mulamba Kabeya Clement 
Published: March 2023

AbstractThis paper examined the role of male partners in modern contraceptive use by women across clusters in South Africa. Its main objective was threefold. First, the present paper sought to test whether South African married women’s modern contraceptive use is related to the influence of their husbands or male partners. Second, it examined whether modern contraceptive use is similar within clusters. Third, it tested whether group effects are spatially dependent among neighbouring clusters. It used the recent Demographic and Health Survey for South Africa as the data source to carry out the empirical analysis. On the one hand, the results confirm a positive and significant relationship between South African married women’s modern contraceptive use with their partners’ secondary education level, irrespective of the cluster in which they reside. On the other hand, the hypothesis that spatial dependence of random effects is not confirmed, leading to the conclusion that space only matters when it comes to spatial heterogeneity or group effects.
Nonconvulsive status epilepticus characteristics in glioma patients: a retrospective study
Authors: Kaneoka Azumi , Fujimoto Satoka Hashimoto , Tamura Kaoru , Inaji Motoki , Maehara Taketoshi 
Published: March 2023

Abstract
Purpose
Epilepsy is a common complication of gliomas. The diagnosis of nonconvulsive status epilepticus (NCSE) is challenging because it causes impaired consciousness and mimics glioma progression. NCSE complication rate in the general brain tumor patient population is approximately 2%. However, there are no reports focusing on NCSE in glioma patient population. This study aimed to reveal the epidemiology and features of NCSE in glioma patients to enable appropriate diagnosis.

Methods
We enrolled 108 consecutive glioma patients (45 female, 63 male) who underwent their first surgery between April 2013 and May 2019 at our institution. We retrospectively investigated glioma patients diagnosed with tumor-related epilepsy (TRE) or NCSE to explore disease frequency of TRE/NCSE and patient background. NCSE treatment approaches and Karnofsky Performance Status Scale (KPS) changes following NCSE were surveyed. NCSE diagnosis was confirmed using the modified Salzburg Consensus Criteria (mSCC).

Results
Sixty-one out of 108 glioma patients experienced TRE (56%), and five (4.6%) were diagnosed with NCSE (2 female, 3 male; mean age, 57 years old; WHO grade II 1, grade III 2, grade IV 2). All NCSE cases were controlled by stage 2 status epilepticus treatment as recommended in the Clinical Practice Guidelines for Epilepsy by the Japan Epilepsy Society. The KPS score significantly decreased after NCSE.

Conclusion
Higher prevalence of NCSE in glioma patients was observed. The KPS score significantly decreased after NCSE. Actively taking electroencephalograms analyzed by mSCC may facilitate accurate NCSE diagnosis and improve the activities of daily living in glioma patients.
Understanding the Self-identification of Autism in Adults: a Scoping Review
Authors: Overton Gayle L. , Marsà-Sambola Ferran , Martin Rachael , Cavenagh Penny 
Published: March 2023

AbstractAdults are increasingly self-identifying as autistic, and reporting problems being referred for an autism diagnostic assessment. This scoping review aims to ascertain: (1) what research has been conducted on the self-identification process of autism in adults, who do and do not have a formal diagnosis of autism, and (2) which aspects of the self-identification process could be used to improve the referral and the diagnostic process of an adult autism assessment. The main themes identified were: the diagnostic process from a client´s perspective; the process of self-identifying as autistic from a lifespan perspective; an autistic identity; sexual identity and experiences, and the perception of autism as a difference or a disability. These themes could positively enhance the referral and diagnostic process.
The effect of controllable train-tail devices on the longitudinal impulse of the combined trains under initial braking
Authors: Zhang Yuan , Wei Wei , Liu Boyang , Zhang Jun , Zhu Jichao 
Published: March 2023

AbstractThe 20,000-ton combined train running has greatly promoted China’s heavy-haul railway transportation capability. The application of controllable train-tail devices could improve the braking wave of the train and braking synchronism, and alleviate longitudinal impulse. However, the characteristics of the controllable train-tail device such as exhaust area, exhaust duration and exhaust action time are not uniform in practice, and their effects on the longitudinal impulse of the train are not apparent, which is worth studying. In this work, according to the formation of the Datong–Qinhuangdao Railway, the train air brake and longitudinal dynamics simulation system (TABLDSS) is applied to establish a 20,000-ton combined train model with the controllable train-tail device, and the braking characteristics and the longitudinal impulse of the train are calculated synchronously with changing the air exhaust time, exhaust area, and action lag time under initial braking. The results show that the maximum coupler force of the combined train will decrease with the extension of the continuous exhaust time, while the total exhaust time of the controllable train-tail device remains unchanged; the maximum coupler force of the combined train reduces by 32.5% with the exhaust area increasing from 70% to 140%; when the lag time between the controllable train-tail device and the master locomotive is more than 1.5 s, the maximum coupler force of the train increases along with the time difference enlargement.
On wave–current interaction in deep and finite water depths
Authors: Kumar Arun , Hayatdavoodi Masoud 
Published: March 2023

AbstractInteraction of linear and nonlinear, long-crested waves with currents in deep and finite water depths is studied by use of the computational fluid dynamics approach. Various wave conditions are considered by systematically changing the wave height and the wavelength. Several current profiles are studied as polynomial functions of water depth following the profiles and magnitudes of the available ocean current data. Both following and opposing currents are considered, and in total, 26 wave–current configurations are investigated. The two-dimensional study is carried out computationally by solving the Navier–Stokes equations for a laminar flow. The governing equations are solved by use of the finite volume approach in an open-source computational fluid dynamics package, namely OpenFOAM. Modifications are made to an existing wave-making toolbox, waves2Foam, to generate combined nonlinear waves and currents in deep and finite waters. Results of the numerical wave–current tank are compared with the existing laboratory measurements and overall very good agreement is observed. Discussion is provided on the effect of these currents on the change of the wave field, including quantitative change of the surface elevation, wave profile, pressure distribution, and fluid particle velocity of waves. Overall, it is observed that opposing current has a remarkable impact on the wave field, and the particle velocity and wave height are affected the most from the presence of the current.
Occurrence of Eutypella species on cotton (Gossypium hirsutum L.) in New South Wales, Australia
Authors: Le Duy Phu , Gregson Aphrika , Madden Anna , Jackson Rodney 
Published: March 2023

AbstractWe report for the first time the occurrence of an Eutypella species on cotton in New South Wales (NSW), Australia. The putative Eutypella was isolated from dead cotton plants that exhibited atypical symptoms of either Fusarium or Verticillium wilt. Dead plants had symptoms resembling lightning strike damage with blackened outer bark around the fifth node zone. Internal vascular discoloration was reddish grey and often occurred in V-shaped sections. Sequences of the internal transcribed spacer (ITS) revealed a 93.7–94.1% similarity to Eutypella scoparia, indicating that the NSW cotton isolates represented a putatively novel species within the Eutypella genus. Pathogenicity of the isolated Eutypella was assessed on cotton stem cuts and living plants inoculated with culture agar plugs. Typical black necroses on outer bark and reddish vascular discoloration were reinduced in both Eutypella-inoculated stem cuts and living plants. Subsequently, the same Eutypella pathogen was successfully recovered, thus fulfilling Koch’s postulates. The detection of Eutypella on NSW cotton is believed to be an independent event from a recently reported occurrence of Eutypella on Queensland cotton. The Queensland detection occurred in the same 2017/18 cropping season at approximately 730 km apart and was associated with distinct Eutypella isolates.
Conducting Violence Research Across Multiple Family Generations and with Young Children: Findings from a Mixed-Methods Pilot Study in South Africa
Authors: Franchino-Olsen Hannabeth , Christofides Nicola , Woollett Nataly , Fouche Ansie , Silima Mpho , Thurston Christina , Monaisa Kopano , Meinck Franziska 
Published: March 2023

AbstractThis paper presents findings from a pilot study focused on examining intergenerational violence in a three-generation sample, which included young children, in a rural area of South Africa. The aims of the pilot study were to investigate the feasibility of participant recruitment, consent, and interviewing; length and burden of the study questionnaires; appropriateness and acceptability of the measures used; and young children’s (age 4–7) ability to comprehend the measures and participate meaningfully in interviews asking about violence. Data were collected for 4 months with three groups of participants, often within families (young adults, their children, and the young adults’ former caregivers), using cognitive interviews, quantitative questionnaires, and qualitative in-depth interviews. All groups participated in arts-based methods and child interviews included visual and tactile aids. Pilot study findings demonstrated feasible recruitment within families for a three-generation study using comprehensive consent protocols and mandatory reporting information. Adults and young children were able to participate in the extensive interviews (2–3 h and 1 h, respectively) without significant burden. The employed measures were appropriate and acceptable to the setting, though minor revisions were made to improve comprehension of certain items. Young children were able to engage and participate meaningfully in the research, though they were not able to answer abstract reasoning items in cognitive interviews and children who were less developmentally advanced required more play- and arts-based accommodations to support their participation. Future research around sensitive topics, such as violence, appears feasible within families and including young children as participants even in resource-poor settings.
Computer Vision Based Automatic Margin Computation Model for Digital Document Images
Authors: Guha Abhijit , Samanta Debabrata , Sengar Sandeep Singh 
Published: March 2023

AbstractMargin, in typography, is described as the space between the text content and the document edges and is often essential information for the consumer of the document, digital or physical. In the present age of digital disruption, it is customary to store and retrieve documents digitally and retrieve information automatically from the documents when necessary. Margin is one such non-textual information that becomes important for some business processes, and the demand for computing margins algorithmically mounts to facilitate RPA. We propose a computer vision-based text localization model, utilizing classical DIP techniques such as smoothing, thresholding, and morphological transformation to programmatically compute the top, left, right, and bottom margins within a digital document image. The proposed model has been experimented with different noise filters and structural elements of various shapes and size to finalize the bilateral filter and lines and structural elements for the removal of noises most commonly occurring due to scans. The proposed model is targeted towards text document images and not the natural scene images. Hence, the existing benchmark models developed for text localization in natural scene images have not performed with the expected accuracy. The model is validated with 485 document images of a real-time business process of a reputed TI company. The results show that $$91.34\%$$

91.34
%

of the document images have conferred more than $$90\%$$

90
%

IoU value which is well beyond the accuracy range determined by the company for that specific process.
Current Clinical Trials for the Monkeypox Virus
Authors: Kandeel Mahmoud 
Published: March 2023

Abstract
Background
Monkeypox (MPX) is a zoonotic Orthopoxvirus causing smallpox-like symptoms. Before April 2022, MPX cases outside Africa were rare. The virus can spread through skin-to-skin contact, sexual contact, respiratory droplets, and household items such as towels and blankets.

Aim
This study was aimed at highlighting the dire need for vaccination and treatment against this infection. Several in-process clinical trials that may help overcome MPX infection are discussed.

Methods
A search for recent clinical studies was conducted in the clinicaltrials.gov database.

Results
A total of 15 trials were identified. After February 2022, 14 new trials were launched. Of the 15 trials, 9 were observational studies, 3 were treatment studies and 3 were preventive studies. MPX clinical trial topics were classified into four broad categories: MPX virus shedding and clearance; response to MPX vaccine; antiviral treatment for MPX; and awareness regarding MPX. One medication, tecovirimat, and two vaccines are currently in clinical trials.

Conclusions
Few treatments and vaccines are under evaluation. Although multiple trials have been conducted, evidence to determine the present state of MPX infection is currently insufficient. Global collaboration is required to achieve complete understanding of the epidemiology, prevention and control of MPX.