bluuebunny/crossref_metadata_2025_split huggingface dataset:
Biodegradasi Hidrokarbon Crude Oil di Kawasan PT. Bumi Siak Pusako-Pertamina Hulu menggunakan Konsorsium Bakteri Indigen
Authors: Novianty Riryn 
Published: July 2023

Riau Province is one of the largest producing areas of crude oil. Drilling and refining petroleum often produce waste crude oil in large quantities. One method that can be used to degrade waste is biodegradation using a consortium of microorganisms. This study examined the effectiveness of a consortium of indigenous bacteria in degrading hydrocarbon compounds. Growth tests and the ability of isolates to degrade hydrocarbons were carried out by inoculating isolates in liquid Bushnell Haas media containing crude oil of about 5% and incubating for 16 days. The potency of the indigen bacterial consortium during the degradation process is influenced by several parameters, including pH, OD (Optical Density), dan CO2 observed on days 0, 4, 8, 12 and 16 days of incubation. KB4 is the superior consortium in degrading hydrocarbon crude oil. Based on the analysis using GC-MS instruments, the bacteria consortium can degrade two hydrocarbon compounds in crude oil.
Relationship Between Paraoxonase-1 Genotype and Activity, and Major Adverse Cardiovascular Events and Malignancies in Patients With Rheumatoid Arthritis Receiving Tofacitinib
Authors: Charles-Schoeman Christina , Hyde Craig , Guan Shunjie , Parikh Neil , Wang Jennifer , Shahbazian Ani , Stockert Lori , Andrews John 
Published: July 2023

ObjectiveThis posthoc analysis investigated the relationship between paraoxonase-1 (PON1) genotype and activity, and risk of major adverse cardiovascular events (MACE) and malignancies in clinical studies of tofacitinib in patients with rheumatoid arthritis (RA).MethodsData were pooled from 9 phase II/III studies and the associated long-term extension studies (all completed by October 2017). PON1 activities in plasma were measured using paraoxon (paraoxonase activity), dihydrocoumarin (lactonase activity), and phenylacetate (arylesterase activity) as substrates. PON1 Q192R genotype effect on baseline PON1 activity was assessed using linear regression for each study, with fixed-effects metaanalysis across studies. MACE and malignancy risk by time-varying enzyme activity was determined using Cox proportional hazards regression.ResultsThe analysis included 1969 patients with RA. Compared with the QQ genotype, the RR genotype had a significant positive association with baseline paraoxonase activity and a significant negative association with baseline lactonase and arylesterase activity (allP< 0.001). Time-varying models demonstrated a significant association of increased paraoxonase activity over time with lower risk of MACE (P< 0.001) and malignancies (excluding nonmelanoma skin cancer [NMSC];P≤ 0.05), even after controlling for risk factors identified in univariate analysis and RA disease activity. A similar trend was observed for lactonase and arylesterase for MACE.ConclusionHigher paraoxonase activity over time was associated with significantly reduced risk of future MACE and malignancies (excluding NMSC), but not NMSC, in patients with RA receiving tofacitinib. Further investigation of PON1 as a novel functional lipid biomarker of MACE/malignancy risk in patients with RA is warranted. (ClinicalTrials.gov:NCT01059864,NCT00550446,NCT00687193,NCT00960440,NCT00814307,NCT00856544,NCT00853385,NCT00847613,NCT01039688,NCT00413699,NCT00661661)
Corruption et quête de bonheur : l’anthropologie au cœur des divisions protestantes du xixe siècle
Authors: Scholl Sarah 
Published: July 2023

Au xixe siècle, le péché originel est un des éléments centraux des débats entre protestants évangéliques, orthodoxes et libéraux. Il prend une place centrale dans la prédication des pasteurs du Réveil, qui secoue l’ensemble du monde réformé. Chez les rationalistes et les libéraux, il est par contre oublié ou contourné. Pourquoi cette différence ? Que se joue-t-il autour de cette thématique, entre bouleversements anthropologiques, ecclésiologiques et conception concurrente de la « chrétienté ». Cet article analyse du matériel issu des différentes tendances et cultures réformées, en particulier des manuels de catéchisme, des liturgies et des sources institutionnelles.
La crise du péché originel à l’heure du concile
Authors: Sorrel Christian 
Published: July 2023

Le questionnaire adressé en 1966 aux conférences épiscopales par le pro-préfet de la Congrégation pour la doctrine de la foi Ottaviani sur les « opinions étranges et audacieuses » intègre la question du péché originel. Celle-ci pose problème depuis longtemps déjà à de nombreux théologiens que le pape Paul VI invite à défendre la doctrine traditionnelle lors d’un symposium romain en juillet de la même année. Le dossier de préparation de la réponse de la conférence épiscopale française confirme le malaise. Mais la réponse officielle reste en retrait pour ne pas compromettre les fruits du concile Vatican II. Les conférences de l’Allemagne, de l’Italie, de l’Espagne, de la Suisse et du Canada accordent peu de place à la question. Il n’en est pas de même pour celles de la Belgique et des Pays-Bas qui prennent leurs distances avec la thèse romaine. Cela n’empêche pas le pape de réaffirmer le dogme du péché originel dans son Credo de juin 1968.
Effect of spine frame on the changes in respiratory dynamics in prone patients under general anaesthesia- a prospective, observational study
Authors: Kandasamy Preeti , Pujari Vinayak S. , Channaiah Sandya Rani D. 
Published: July 2023

Background and Aims:
The prone position is one of the common surgical positions used in clinical practice. Manoeuvring patients from supine to a prone position can impact respiratory dynamics and result in haemodynamic variations.

Methods:
This study included 64 patients and was conducted after obtaining approval from the ethics committee and registration of the trial. The primary objective was to evaluate the changes in peak inspiratory pressure (PIP), plateau pressure (Pplat) and mean airway pressure (MAP) in patients undergoing surgery under general anaesthesia in the prone position with (Group S) and without (Group P) spine frame. The secondary objective was to evaluate and compare the variations in heart rate and blood pressure.

Results:
On turning the patient prone, there was statistically significant increase in median PIP (Group S 4 cmH2O vs. Group P 0.5 cmH2O, P < 0.001), Pplat (Group S 3.5 cmH2O vs. Group P 1 cmH2O, P = 0.004) and dynamic compliance (Group S −5.513 vs. Group P −2.78, P < 0.004).

Conclusions:
Our study found that prone positioning with a spine frame led to a significantly greater increase in airway pressures and a decrease in dynamic compliance when compared to patients positioned prone without the spine frame.
Ultrasound-guided anterior suprascapular nerve block versus interscalene brachial plexus block for arthroscopic shoulder surgery: A randomised controlled study
Authors: Gupta Kapil , Gupta Malvika , Sabharwal Nikki , Subramanium Balavenkat , Belani Kumar G. , Chan Vincent 
Published: July 2023

Background and Aims:
The interscalene brachial plexus block (ISB) affects the phrenic nerve, resulting in hemi-diaphragmatic paresis (HDP) and, possibly, respiratory distress. Suprascapular nerve block via an anterior approach (SSB-A) is performed more distally at the level of the trunk of the brachial plexus and, thus, may spare the phrenic nerve. This study compares the analgesic efficacy and decline of hemi-diaphragmatic excursion (HDE) following ultrasound (US)-guided SSB-A versus ISB for arthroscopic shoulder surgery.

Methods:
This study was conducted on 60 adult participants undergoing arthroscopic shoulder surgery under general anaesthesia. Both US-guided SSB-A (n = 30) and ISB (n = 30) were performed with a combination of 10 ml bupivacaine (0.5%) and 4 mg dexamethasone. The primary objective was to compare the duration of analgesia (time to first rescue analgesia), and secondary objectives were to compare 24-h postoperative numerical rating scale (NRS) scores, 24-h morphine consumption and post block change in HDE, and pulmonary function tests (PFTs) between the two groups. For analysing intergroup differences of NRS, HDE and PFT; Pearson’s Chi-squared test or Fisher’s exact test, unpaired t test, and Mann–Whitney U test were used. For intragroup differences, paired t test was used. A P value <0.05 was considered significant.

Results:
The duration of analgesia (mean ± Standard Deviation) was similar in two groups (SSB-A = 1,345 ± 182 min, ISB = 1,375 ± 156 min; P = 0.8). The reduction in HDE was significantly greater in the ISB group (44%) than in the SSB-A group (10%). Pulmonary function was better preserved in the SSB-A group.

Conclusion:
Compared to ISB, SSB-A has a similar analgesic efficacy for arthroscopic shoulder surgeries, but it is superior in preserving diaphragmatic function and pulmonary function.
Incidence of postoperative pulmonary congestion as diagnosed by lung ultrasound in surgeries performed under general anaesthesia: A prospective, observational study
Authors: Basumatary Kartik , Dey Samarjit , Neema Praveen K. , Mujahid Omer M. , Arora Prateek , Kalbande Jitendra 
Published: July 2023

Background and Aims:
Administering liberal fluid raises concerns about pulmonary congestion postoperatively. Bedside ultrasonography is a valuable tool for the early detection of pulmonary congestion. In this study, we have used it to ascertain the impact of the duration of surgery and intraoperative fluid volume on the causation of pulmonary congestion. Our objective was to determine the incidence of pulmonary congestion as diagnosed by lung ultrasound in patients undergoing general anaesthesia with varied fluid administration.

Methods:
Seventy participants of American Society of Anesthesiologists physical status I and II, aged between 18 and 60 years, undergoing elective extrathoracic surgeries of over 3 h under general anaesthesia were included. Preoperative lung ultrasound was carried out in all patients, and a postoperative lung ultrasound was carried out at 1 h after extubation. The appearance of three or more “B”-lines was considered positive for lung congestion.

Results:
Significant differences (P < 0.001) were found in the duration of surgery and the appearance of B-lines in the postoperative period. Participants who developed B lines received, on average, 150% more fluid (1148.16 ± 291.79 ml) than those who did not (591.29 ± 398.42 ml) (P = 0.0240). Net fluid balance was also significantly different in patients who developed B lines (P = 0.0014). None of the patients developed symptoms of lung congestion postoperatively.

Conclusion:
Long duration of surgery under general anaesthesia (>3 h) with the administration of large volumes of intraoperative fluid and a large net fluid balance are associated with lung congestion as diagnosed by lung ultrasound.
Efficacy of analgesia using ilioinguinal–iliohypogastric (IIIH) nerve block, transversus abdominis plane (TAP) block and diclofenac after caesarean delivery under spinal anaesthesia: A non-randomised clinical trial
Authors: Singh Ranju , Yadav Kavita , Singh Pooja 
Published: July 2023

Background and Aims:
Our aim was to assess the efficacy of analgesia using ilioinguinal–iliohypogastric (IIIH) nerve block, transversus abdominis plane (TAP) block and diclofenac after caesarean delivery (CD) under spinal anaesthesia (SA).]

Methods:
A total of 457 healthy parturients undergoing CD under SA were included in this prospective, observational study. Groups differed in the postoperative analgesic strategies received by the parturient at the end of surgery: group D (n = 148) received intramuscular diclofenac sodium, group I (n = 153) received bilateral IIIH block with bupivacaine plus clonidine and group T (n = 156) received bilateral TAP block with bupivacaine plus clonidine. Total duration of postoperative analgesia, numerical pain rating scale (NRS) scores, patient satisfaction score, rescue analgesics in the first 48 h postoperatively and adverse effects were observed. A value of P < 0.05 was taken as significant.

Results:
Total duration of analgesia was longest (18.2 ± 1.3 h) in group T and shortest in group D (6.3 ± 0.8 h) compared to group I (13.1 ± 1.2 h) (P < 0.001). Total analgesic requirement in postoperative 48 h was lowest in group T (152.1 ± 34.9 mg), highest in group D (355.0 ± 25.6 mg) and intermediate in group I (221.0 ± 30.0 mg) (P < 0.001). Mean NRS scores were lower in group T compared to those in groups D and I. The patients in group T were extremely satisfied, in group I were satisfied and in group D were dissatisfied (P < 0.001).

Conclusion:
Bilateral TAP block with bupivacaine and clonidine after CD under SA increases the duration of postoperative analgesia.
The analgesic effects of bilateral superficial cervical plexus block in thyroid surgery: A systematic review and meta-analysis
Authors: Wilson Laura , Malhotra Rajiv , Mayhew David , Banerjee Arnab 
Published: July 2023

Background and Aims:
Thyroid surgery is moderately painful, and many techniques to reduce postoperative pain have been studied. Regional techniques are a part of multimodal analgesia employed for various surgical cases. Bilateral superficial cervical plexus block (BSCPB) is a commonly used regional anaesthesia technique for analgesia for thyroid surgery. A previous meta-analysis by this group had left questions about some facets of the technique, to which further trials have contributed.

Methods:
The systematic review and meta-analysis was registered on the International Prospective Register of Systematic Reviews (PROSPERO) CRD42022315499. It is an update to a previously published paper in 2018. An updated systematic search, critical appraisal, and analysis of clinical trials were performed. Trials investigating preoperative or postoperative BSCPB compared to control in patients undergoing thyroid surgery were included in the search. The primary outcome was postoperative opioid consumption. The secondary outcomes were the duration of analgesia (time to request of analgesia), Visual Analogue Scale (VAS) pain scores at 0, 4, 12, and 24 h, postoperatively, rates of postoperative nausea and vomiting (PONV), postoperative rescue analgesic consumption, and intraoperative morphine use.

Results:
A total of 31 studies and 2,273 patients were included in this analysis. BSCPB significantly reduced post-thyroidectomy opioid consumption (P < 0.001). Additionally, the duration of analgesia was prolonged following BSCPB. VAS scores for 24 h (postoperatively), intraoperative morphine use, and rescue analgesia (postoperatively) remained significantly lower in patients who received BSCPB. There was also a statistically significant reduction in PONV (P = 0.02).

Conclusion:
BSCPB offers superior postoperative analgesia with a reduction in opioid use, reduction in PONV, and improvement in VAS scores.
An Observational Study of Charakokta Angula Pramana for Standardization of Shirogreevagata Pratyanga
Authors: Bhawana Joshi  , Naresh Kumar  , Sanjay Kumar  , D.C.Singh  
Published: July 2023

Ayurveda is a science of life that deals with prevention and cure of diseases. To unscrew the pathology of various diseases, a thorough understanding the structural and functional built of the human physique is inevitable. To achieve such goals there should be knowledge of body (Sharir), body parts (Anga and Pratyanga) and their Pramana (anthropometry). Angula Pramana is determined by measuring the height (Utsedha), length (Ayam), breadth (Vistar) and circumference (Parinah) of Pratyangas. Here finger breadth of the individual (i.e. Swa-Angula) is used as the reference unit of measurement. Anthropometry measurement of the human body means measurement of height and weight where Acharya Charaka, Sushruta, and Vagbhatt have given different values of human height which is 84 Angula, 120 Angula, 31/2 Hasta respectively. The study was conducted on 200 healthy volunteers in age group of 18-50years. One Angula as a unit of Angula Pramana was obtained by measuring the width of Madhyamparva of middle finger of working hand. The measurements were taken in centimetres for standardization as per metric system. This article summarizes the facts related to Anguli Pramana from classical, Ayurvedic and modern literature along with result of our research work to identify the anatomical landmark of Sheerogreevagata Pratyanga measured through Anguli Pramana and its applied aspect. At present, there are many physical anomalies i.e., genetic, endocrine, congenital, developmental disorders and traumatic injury which results as anatomical disfiguration of Shira and Greeva that can distinguish from their Anguli pramana or anthropometry.
A Comprehensive Management of Dushta Vrana Vis-A-Vis Diabetic Ulcer - A Case Study
Authors: Chaithra H B  , Yatish K H  
Published: July 2023

Vrana is a clinical condition which occupies the area of skin and remains till body survives. Dushta Vrana is the Vrana having the features of Durgandha (bad smell), Pooyayukta (pus filled), Utsangi (elevated), Chirakali (chronic), Dooshita (afflicted by Tridosha vitiation), Atigandha Varna Srava (discharge with excessive odour and coloured), Vedanayukta (painful) and opposite to Shuddha Vrana (healing wound). Diabetic foot ulcer global prevalence is 6.3% with male predominancy and higher in type 2 diabetic patients (6.4%) than in type 1 diabetics (5.5%).
In this report, a 70-year-old who was diagnosed with chronic non-healing diabetic wound treated with comprehensive Ayurvedic medicines based on the observations made on the nature of the wound. The main cause for the wound was uncontrolled type 2 diabetes mellitus, which was managed with both Ayurveda and conventional drugs. Patient gradually showed improvement. Total healing required 6 months.
MÜELLİFİ BİLİNMEYEN MANZUM BİR SÂ’ATNÂME: ESRÂR-I EYYÂM
Authors: CAN EMMEZ Berivan , SÜSLÜ Zahir 
Published: July 2023

Teknoloji ve tekniğin gelişmediği dönemlerde insanlar evlenmek, ekip biçmek, sefere çıkmak, savaşmak, sulh etmek gibi birey ve toplum hayatını belirleyen önemli olay ve durumların akıbetini öğrenmek için çeşitli yollara başvurmuşlardır. Bu merak duygusu ve yapılacak eylemlerin iyi sonuçlar doğurması yönündeki arzu insanları çeşitli yollara sevk etmiştir. Bunun neticesi olarak özellikle Kur’ân-ı Kerîm, hadîs-i şerîf ve muteber kimselerin eserlerinden delil çıkarılarak bir takım kılavuz eserler yazılmıştır. Melhameler, tabiatnâmeler, falnâmeler, tabirnâmeler, yıldıznâmeler, seğirnâmeler (ihtilacnâmeler), kıyafetnâmeler, sâ’atnâmeler bu eserlerden bazılarıdır.
Bu çalışmanın konusu; Milli Kütüphane Yazmalar Koleksiyonu 06 Mil Yz A 4077/3 demirbaşta kayıtlı, Esrâr-ı Eyyâm isminde bir sâ’atnâmedir. 106 beyitten müteşekkil olan eser, mesnevi nazım şekliyle yazılmış olup yazarı meçhuldür. Çalışmada, eserin künye bilgileri ile birlikte şekil özellikleri ve muhtevası, dil ve üslup özellikleri hakkında bilgi verilip Latin harfli çevirisi aktarılmıştır.
ESTÁGIO SUPERVISIONADO EM COMPUTAÇÃO II: UTILIZANDO A PLATAFORMA KAHOOT COMO FERRAMENTA DE APRENDIZAGEM PARA ENSINO TÉCNICO NO CURSO DE SEGURANÇA NO TRABALHO
Authors: Esmeraldo Marques Luis Carlos , Rodrigues Fonte Kamila , Conrado de Souza Ivone , Sérgio de Oliveira Barbosa Luiz 
Published: July 2023

Este artigo aborda a notoriedade do estágio supervisionado para a preparação acadêmica. Essa atividade prática foi realizada pelo ensejo da aplicação da disciplina de Estágio Supervisionado em Computação II, do curso de Licenciatura em Computação, no Núcleo de Ensino Superior de Careiro Castanho (NESCAC), da Universidade do Estado do Amazonas (UEA). A Lei de Diretrizes e Bases da Educação Nacional (LDB) estabelece a obrigatoriedade da disciplina como componente curricular do curso. Os estágios oferecem aos alunos oportunidade de aplicar experiências na prática, obter exposição direta às realidades profissionais e construir identidades de professores. A supervisão de estágio perpassa todo o processo do estágio I e II, incluindo observação da classe e suas salas de aula, coparticipação na implementação das atividades conforme o acordo e assunto abordado com o professor e, por fim, a regência. Foi explorada a utilização da plataforma Kahoot, ferramenta de aprendizagem baseada em jogos, no Curso Técnico de Segurança do Trabalho, com o propósito de tornar o aprendizado mais dinâmico e envolvente. A plataforma permite a criação de atividades no formato de quiz, que fornecem feedback imediato aos alunos e auxiliam na avaliação do conhecimento. A utilização do Kahoot permite a compreensão do conteúdo e incentiva a participação dos estudantes. A tecnologia tem desempenhado um papel importante no ensino atual, confiante para o aprendizado dos alunos e tornando as aulas mais interativas.
Pengembangan Bahan Ajar E-Modul Berbasis Geogebra Untuk Meningkatkan Kemampuan Berpikir Visual Siswa
Authors: Geo Wahyuni  , Rita Destini  , Abdul Mujib  
Published: July 2023

Penelitian ini dilakukan bertujuan untuk menghasilkan produk bahan ajar e-modul yang valid, efektif dan praktis serta dapat meningkatkan kemampuan berpikir visual siswa. Dalam penelitian ini menggunakan metode penelitian Research and Development (R&D) dengan melalui tahapan ADDIE. Teknik pengumpulan data menggunakan angket ahli materi, ahli media, respon guru dan respon siswa serta hasil penilaian di awal (pretest) dan setelah pembelajaran (posttest). Pelaksanaan penelitian dilakukan pada siswa kelas XI SMK Negeri 1 Sei Rampah dengan sampel 36 orang siswa. Adapun hasil dari penelitian ini menunjukkan bahwa validasi dari ahli media sebesar 82,50% dan ahli materi sebesar 81,00%. Hasil dari respon siswa sebesar 91,82% untuk kepraktisan dan 81,17% untuk kefektifan. Untuk hasil respon guru sebesar 85,45% untuk kepraktisan dan 82,50% untuk kefeketifan. Sedangkan hasil rata-rata dari pretest sebesar 31,25 dan rata-rata postest sebesar 80,28 dengan N-Gain score sebesar 70,09%. Ini menunjukkan bahwa bahan ajar e-modul berbasis Geogebra berpengaruh dalam meningkatkan kemampuan berpikir visual dalam kategori sedang.
Thiết kế tình huống dạy học chương tam giác theo hướng phát triển năng lực giải quyết vấn đề toán học cho học sinh lớp 7
Authors: Nguyễn Dương Hoàng , Dương Thị Thu Thảo 
Published: July 2023

Năng lực giải quyết vấn đề toán học là một trong những năng lực toán học cốt lõi cần được hình thành và phát triển cho học sinh phổ thông. Do vậy, để phát triển năng lực này cho học sinh, giáo viên cần xây dựng các tình huống dạy học phù hợp trong dạy học. Bài viết này xác định các biểu hiện Năng lực giải quyết vấn đề toán học của học sinh trong học tập chương Tam giác. Thiết kế tình huống dạy học khái niệm, định lý theo hướng phát triển năng lực giải quyết vấn đề toán học. Việc thiết kế tình huống dạy học theo hướng phát triển năng lực giải quyết vấn đề toán học cho học sinh giúp các em nâng cao năng lực giải quyết vấn đề toán học , ứng dụng trong thực tiễn cuộc sống.
Mundos relacionales no antrópicos en “La quema” de Andrea Mejía y “Un toro bien bonito” de Laura Ortiz Gómez
Authors: Aristizábal Juanita Cristina 
Published: July 2023

Este artículo analiza cuentos de Andrea Mejía y Laura Ortiz Gómez a través de algunos debates sobre el Antropoceno desde las ciencias sociales y naturales que hablan de la necesidad de una transición hacia un planeta más habitable de relaciones entre especies y de ontologías relacionales. El análisis sitúa los cuentos de Mejía y de Ortiz Gómez en el contexto del llamado pos-conflicto colombiano —el período después de la firma del Acuerdo de Paz que terminaría con el conflicto armado de más larga duración en el hemisferio occidental— y de la reciente entrega de los resultados de años de trabajo con las víctimas de este conflicto por parte de la Comisión de la Verdad creada a raíz de este acuerdo. La lectura de los cuentos subraya cómo Mejía y Ortiz Gómez exploran la literatura como un espacio para reflexionar sobre la violencia rural en Colombia, para imaginar una reconciliación con la naturaleza como otra de las víctimas del conflicto y futuros posibles más allá de la división entre naturaleza y cultura y de las ontologías que, al poner la vida humana en el centro, han demostrado ser nocivas en la actual catástrofe ecológica y climática que enfrentamos.