bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of ischemic injury characteristics on left ventricular systolic function in patients with acute myocardial infarction
Authors: Oleinikov V. E. , Salyamova L. I. , Donetskskaya N. A. , Vdovkin A. V. 
Published: September 2023

Aim. To study laboratory and magnetic resonance imaging (MRI) characteristics of infarction area depending on left ventricular (LV) global systolic function in patients with acute myocardial infarction (AMI) after revascularization.Material and methods. A total of 78 patients with primary AMI were included. On days 7-10, contrast-enhanced cardiac MRI was performed. Blood brain natriuretic peptide (BNP) was analyzed. Cardiac MRI was used to determine the characteristics of scar tissue, peri-infarct zone (PIZ), microvascular obstruction (MVO), intramyocardial hemorrhage (IMH) and the global contrast index.Results. According to the MRI, patients were divided into following groups: group 1 — LV ejection fraction (LVEF) ≥50% (n=50), group 2 — LVEF 40-49% (n=21), group 3 — LVEF <40% (n=7).The BNP in groups 1, 2, 3 was 106,8 (37,5; 248), 232,6 (170,1; 337,7) and 548,5±236,4 ng/ml, respectively (p1-3<0,05). The scar tissue mass in groups 1, 2, 3 was 10,3 (2,4; 20,0), 34,7±21,3, 59,4±37,6 g, respectively (p1-2, 3<0,01). PIZ differences were found only between patients with preserved and mildly reduced EF. MVO was diagnosed in 26% of patients with LVEF ≥50%, in 47,6% of patients with LVEF of 40-49% and 85,7% with LVEF <40% (p1-3<0,01). The detection rate of IMH prevailed in the 2nd group (33,3%) compared with the 1st group (12%) (p1-2<0,05). The global contrast index was the lowest in the 1st group (14,7 (8,8; 27,9)%), intermediate in the 2nd group (33,3±12,6%), the highest in the 3th group (54,2±19,5%) (р1-2, 3; 2-3<0,05).Conclusion. The following risk factors for a decrease in LV systolic function in patients with AMI after revascularization were identified: the size of scar tissue, PIZ, MVO and IMH characteristics, global contrast index, BNP level.
Study of prevalence and antimicrobial susceptibility pattern of blood culture isolates from a tertiary care hospital in South India
Authors: Mustafa Maimoona , Anjum Iqra 
Published: September 2023

Bloodstream infections progress rapidly to life threatening septicemia and sepsis and hence appropriate rapid management is crucial. A prospective study was carried out in the department of microbiology where patients with clinical suspension of bacteremia were enrolled and blood culture was performed. The isolates were identified by phenotypic characters and antimicrobial susceptibility performed. A total of 1200 blood samples were collected out of which 279 were positive for aerobic bacterial growth. was the most commonly isolated organism followed by and . Gentamicin (81.6%), Levofloxacin (75%), Meropenem (88.5%) and (93.8%) showed higher sensitivities when compared to Cephalosporins (55%-68%) and penicillin. Gram-negative bacteria have high resistance rates and discordant antibiotic treatment can lead to multi-organ involvement. Proper timely institution of empirical treatment and adherence to antimicrobial stewardship guidelines coupled with aggressive management is crucial in saving lives.
Prevalence and molecular characterization of carbapenem resistant gram-negative bacilli in a tertiary care hospital in Mumbai
Authors: Prabhala Srujana , Sundaresan Aarthi , Varaiya Ami 
Published: September 2023

Carbapenem (CR) among gram-negative bacteria is a worldwide problem. It is ranked in the highest priority category in the World Health Organization (WHO) global priority list of pathogens.It is responsible for therapeutic failure in both hospital and community-acquired infections.Identifying and monitoring the local epidemiology of the carbapenem resistant organisms, understanding specific mechanisms underlying the resistance and implementing measures to prevent their spread is the need of the hour.The aim of the study was to determine the prevalence and molecular epidemiology of Carbapenem resistant Gram negative bacilli in this hospital.: A retrospective study was carried out in the Department of Microbiology of a tertiary care Hospital in Mumbai from January to December 2022. All Gram negative bacilli from various specimens were identified and antimicrobial susceptibility was reported using the VITEK2 automated system (BioMerieux, Durham, North Carolina) and interpreted as per CLSI 2022 guidelines. The resistant genes in the isolates were detected by Xpert Carba-R assay (Cepheid, Sunnyvale, CA) on request by a consulting physician.: Out of 2,351 gram negative bacilli isolates, 624 were Carbapenem resistant (26.5%). (59.9%) was the most common CR isolate. Molecular testing was done for 190 of these 624 CR isolates. In which New Delhi Metallo beta lactamase (NDM (33.68%) was the most common resistant gene identified followed by NDM & OXA-48(32.63%). With the prevalence of Carbapenem resistant isolates in the settings, adherence to infection control practices and stringent implementation of antimicrobial stewardship is crucial to curb the rate of infection.
Islamic Religious Education on the Technological Developments of the Era-Revolutionary Society 5
Authors: Wiliyanti Vandan , Rakhmadi Roby , Octavia Sonia 
Published: September 2023

The era of society 5.0 emerged with challenges as well as life obstacles. Society 5.0 has a significant impact on the education sector. Educational institutions are expected to be resilient in the face of emerging changes. Islamic religious education has faced big challenges because the era of society 5.0 puts forth 3 aspects, that of human literacy, data literacy, and technological literacy. The concept of learning Islamic religious education in the era of society 5.0, the benefits of learning this education, and the challenges of it in the era of society 5.0 are the background problems this study explores. This research model uses a literature study or what is commonly referred to as library research and the data collected is reviewed from various sources, including scientific publications and books that focus on these concepts, challenges and innovations of Islamic religious education in society 5.0. The data used are from books and journals. The challenges rose from the fact that there were inadequate human resources and teachers who were mostly elderly. The concepts applied in this learning utilize and create new innovations. The innovation of Islamic religious education learning that is carried out is by using a project-based learning model (PjBL) which is a 21st century learning model based on basic concepts and paradigms. This method is considered to be able to increase students’ motivation in conducting analysis aimed at problem-solving activities and critical thinking.
Keywords: Society 5.0, Islamic religious education, Islamic religious studies, Revolution-era technology.
ASSISTÊNCIA DE ENFERMAGEM A PESSOAS COM FERIDAS CRÔNICAS
Authors: Silva Júnior José Antonio da , Dantas Maiara Bezerra , Abreu Roberta Amador de 
Published: September 2023

Objetivo: relatar a experiência de enfermeiros residentes na assistência de pessoas com feridas crônicas no âmbito da Atenção Primária à Saúde. Método: Trata-se de um relato de experiência de enfermeiros residentes de um Programa Multiprofissional duas Unidades Básicas de Saúde no estado do Rio Grande do Norte, no período dos meses de março de 2020 a fevereiro de 2021. Resultados: Os principais tipos de feridas crônicas atendidas durante o período dessa experiência foram: úlceras vasculogências, lesões oncológicas, lesões por pressão, ostomias e úlceras diabéticas. Como dificuldade foram identificadas a ausência de educação permanente dos profissionais e de insumos/estrutura física adequada das Unidades Básicas de Saúde. Conclusões: Deste modo, o atendimento integral, multiprofissional e centrado no sujeito, muitas vezes é limitado pelas inconsistências e fragmentações observadas na Atenção Primária à Saúde, sendo os programas de Residência uma ferramenta de formação mútua entre os profissionais-residentes, preceptores e gestores dos serviços de saúde.
Mathematical process skills and cooperation character of elementary school students on simple flat building materials
Authors: Kamid Kamid , Kurniawan Dwi Agus , Perdana Rahmat , Citra Yulita Dwi , Rahman Adriyan Ardi , Fadillah Putri 
Published: September 2023

This research was conducted to look at differences in mathematical process skills and the cooperative character of students and the influence between process skills and the character of cooperation. This research was conducted using mixed methods. The instruments in this study were interview sheets and questionnaires to determine process skills and the character of cooperation. Quantitative data was analyzed using the statistical analysis software application and qualitative data using Miles and Huberman. The sample used was 40 students with 20 students in each class. From the results obtained, there is no significant difference between students' mathematical processing skills. It was also found that there was an influence between the nature of collaboration and students' processing abilities. It can be concluded that there is an influence of process skills on the character of student cooperation.
Keywords: Building; building material; mathematics; process skills; simple flat
Lived experiences among high school students in playing 4 pics 1-word mobile game
Authors: Jaca Cristie Ann , Tumulak III Bernardo M. , Boaquin Verner B. 
Published: September 2023

This qualitative study unraveled the lived experiences among Grade-10 students of Tuyan National High School in playing the mobile word game 4 Pics 1 Word. The study made use of the descriptive phenomenological research method that looked into their experiences playing the word game. The data were gathered through one-on-one interviews using researcher-made questionnaires and analyzed using the Braun and Clarke six-phase framework for doing thematic analysis employing semantic and latent approaches. Based on the findings of the study, the themes that emerged from the students' responses were: challenged, engaged, enhanced critical thinking skills, and increased vocabulary skills, which reflect that the 4 Pics 1 Word mobile application is conducive and lucrative for students in learning vocabulary. Moreover, the study found that the students’ experiences in playing 4 Pics 1 Word helped them develop an interest in learning new words and increased their self-confidence in expressing themselves and their ideas.
Keywords: Gamification, mobile games, vocabulary learning, words.
The role of the school principal in burnout and job satisfaction of secondary school teachers in Greece
Authors: Kranioti Anna , Broni Georgia 
Published: September 2023

This research aims to identify the role of school principals in burnout and job satisfaction of Greek teachers that are working in both primary and secondary education. The aim was covered through quantitative research with a structured and online distributed questionnaire used as the main research tool. The research participants were 155 schoolteachers coming from primary and secondary Greek school units. They were collected by using convenience sampling and the avalanche method. For the distribution of the questionnaire, the Google Forms platform was used, and for the statistical analysis. The main research results showed that transactional and transformational leadership are more implemented in Greek schools, than laissez-faire leadership style. Teachers’ levels of job burnout are positively affected by laissez-faire leadership and negatively affected by the two positive leadership styles. On the contrary, transformational, and transactional leadership has a positive impact on job satisfaction levels and a negative impact on teachers’ burnout.
Keywords: Job satisfaction; laissez-faire leadership; teachers; transactional leadership; transformational leadership
Exploring objective measures of overactivity in children with rare genetic syndromes
Authors: O'Sullivan Rory , Bissell Stacey , Agar Georgie , Spiller Jayne , Surtees Andrew , Heald Mary , Clarkson Emma , Khan Aamina , Oliver Christopher , Bagshaw Andrew P , Richards Caroline 
Published: September 2023

Abstract

Background
Overactivity is prevalent in several neurodevelopmental conditions, including Smith-Magenis syndrome, Angelman syndrome, and tuberous sclerosis complex, although has been predominantly measured using questionnaire techniques. Threats to the precision and validity of questionnaire data undermine existing understanding of this behaviour. Previous research indicates objective measures, namely actigraphy, can effectively differentiate non-overactive children from those with attention-deficit hyperactivity disorder. This study is the first to examine the sensitivity of actigraphy to overactivity across rare genetic syndromes associated with intellectual disability, through comparisons with typically-developing peers and questionnaire overactivity estimates.
Methods
A secondary analysis of actigraphy data and overactivity estimates from The Activity Questionnaire (TAQ) was conducted for children aged 4-15 years with Smith-Magenis syndrome (N=20), Angelman syndrome (N=26), tuberous sclerosis complex (N=16), and typically-developing children (N=61). Actigraphy data were summarized using the M10 non-parametric circadian rhythm variable, and 24-hour activity profiles were modelled via functional linear modelling. Associations between actigraphy data and TAQ overactivity estimates were explored, alongside differences in actigraphy-defined activity between syndrome and typically-developing groups, and within-syndrome high and low TAQ overactivity groups.
Results
M10 and TAQ overactivity scores were positively correlated for children with Angelman syndrome, and near-significantly correlated for children with Smith-Magenis syndrome. M10 did not differ between the syndrome and typically-developing groups. Higher early morning activity and lower evening activity was observed across all syndrome groups relative to typically-developing peers. High and low TAQ group comparisons revealed syndrome-specific profiles of overactivity, persisting throughout the day in Angelman syndrome, occurring during the early morning and early afternoon in Smith-Magenis syndrome, and manifesting briefly in the evening in tuberous sclerosis complex.
Discussion
These findings support the sensitivity of actigraphy to overactivity in children with rare genetic syndromes, and provide syndrome-specific temporal descriptions of overactivity. The findings advance existing descriptions of overactivity, provided by existing questionnaire techniques, in children with rare genetic syndromes and have implications for the measurement of overactivity. Future studies should examine the impact of syndrome-related characteristics on actigraphy-defined activity, and actigraphy and questionnaire estimates of overactivity.
Impact of Interprofessional Education for Enhanced Teamwork in OBGYN Emergency: Results from a mixed methods study
Authors: Yasmin Haleema , Malik Shoaib , Ali Syed Moyn , Ali Sobia , Hussaini Anum S. , Baig Lubna Ansari 
Published: September 2023

Abstract
Background
Interprofessional education is a collaborative approach to developing healthcare students as future interprofessional team members and a recommendation suggested by the Institute of Medicine. Complicated medical issues can be best tackled by interprofessional teams, especially when dealing with emergency cases. The study aims to compare the scores on pre and post tests using TeamSTEPPS Teamwork Perception Questionnaire (TTPQ) before and after the implementation of interprofessional education sessions and to explore the perception and attitude transformation of health care providers regarding their teamwork in clinical settings after those sessions.
Method
This mixed method (concurrent embedded) study was conducted at OBGYN department of Jinnah Postgraduate Medical Centre, Karachi, Pakistan from January to April 2022. We conducted a quasi-experimental study to evaluate the six interprofessional teaching sessions of six groups of healthcare professionals, including obstetricians/gynecologists, anesthetists, midwives, operating room nurses, anesthesia technicians, and emergency physicians working in OBGYN emergency in simulated setting based on common OBGYN case scenarios. Participants were scored on TTPQ, a valid assessment tool, both before and after the intervention took place. FGDs and IDIs were conducted in the fifth and sixth weeks of the intervention to understand the feelings, values and perceptions of participants about teamwork during and after attending the sessions.
Results
Total 24 (40%) were males, 36 (60%) were females. The analysis revealed improvement in TTPQ subscales including team function, leadership, situation monitoring, mutual support, and communication (p-value < 0.05). Narratives from interviews identified effective communication and good leadership as core components and indicated that multiple factors can underpin IPE implementation. Results suggest that educational intervention can be challenging in real life unless all stakeholders are dedicated and committed to this approach. If rightly and inclusively implemented this approach, medical education can be very cost effective, pleasant, and critical for better patient outcomes.
Conclusion
Interprofessional education and training sessions were well accepted, suggesting indications of positive engagement towards teamwork. Participants expressed better grasp of teamwork skills, regarding all domains including leadership, management, and communication in obstetric crises.
Analysis and control of vehicle steering wheel vibration based on acceleration transfer path analysis method
Authors: Ye Xiaoming , Wang Yongliang , Liu Hao , Luo Ting , Sun Menglei 
Published: September 2023

Abstract
This paper is aimed to analyze and control the structure vibration of a vehicle steering wheel by using the acceleration transfer path analysis (TPA) method and vibration sensitivity method. A steering wheel vibration test is conducted to obtain the critical engine speed and corresponding to the frequency. The acceleration-acceleration transfer function from mounts body side to steering wheel is deducted and tested, in conjunction with the actual acceleration spectrums of mounts body side, the acceleration spectrum of steering wheel is synthesized and the accuracy of the synthetic results is evaluated high. Then the vibration transmitted by each path is investigated and the main vibration participation paths are picked out from numerous paths. The interaction mechanisms between the path transfer vibration, path vibration participation and the total vibration are further obtained. The critical parameters (mounting stiffnesses and vibration sensitivity) of the main vibration participation paths are matched, modified and the vibration control effect is experimental verified. The results indicate that, by pertinently matching the stiffness parameters of the mounts and reducing vibration sensitivity of structure, the dynamic force transmitted by the paths are decreased, the vibration transfer functions from mounts body side to steering wheel are decreased, and then the actual steering wheel vibration is controlled.
PGE2 promotes ureteral stone expulsion through ureteral relaxation via EP2 receptor
Authors: Su Hao , Zhou Wenyang , Chen Weiming , Yang Ke , Yang Meng , He Hu , Qian Cheng , Yuan Dongbo , Jiang Kehua , Zhu Jianguo 
Published: September 2023

Abstract
This study aimed to assess the relaxant impact of PGE2 on the ureter and whether it becomes a facilitator of calculi expulsion following calculi formation. We identified the presence of EP receptors in the ureter using Western blot and immunofluorescence techniques. In vitro experiments were conducted to assess the impact of PGE2, receptor antagonists, and agonists on the rate of ureteral relaxation. Ureteral calculi models were constructed to gather ureteral tissue from the postoperative side of the obstruction. Western blot analysis was used to assess protein expression levels of EP receptors and the PGE2 terminal synthase mPGES-1. Western blot analysis revealed the presence of EP2 and EP4 protein expression in ureteral smooth muscle. Immunofluorescence revealed predominant localization of EP2 on the cell membrane and EP4 in the nucleus. In vitro experiments demonstrated that PGE2 induced concentration-dependent relaxation of the ureter. EP2 antagonists effectively inhibited the relaxation effect, while EP4 antagonists had no such inhibitory effect. In the presence of ureteral stones, the ureters on the obstructed side can become a favorable factor for stone expulsion by upregulating EP2 expression, enhancing PGE2 synthesis, and promoting ureteral relaxation via cAMP. In conclusion, PGE2 binding to EP2 induces ureteral relaxation, and in the context of ureteral calculi, it serves as a facilitator for stone expulsion.
A Design Strategy for High-performance p-type Two-dimensional Field Effect Transistors
Authors: Das Saptarshi , Das Mayukh , Sen Dipanjan , Venkatram Pranavram , Ghosh Subir , Zhang Zhiyu , Sun Yongwen , Sakib Najam U , Han Ying , Sarkar Kalyan , Pradhan Kumar , Somvanshi Divya , Sofer Zdenek , Yang Yang 
Published: September 2023

Abstract
Doping plays a critical role in tailoring the characteristics of semiconducting materials and electronic devices. Specifically, in the context of field-effect transistors (FETs), degenerate doping in the silicon channel beneath the source and drain regions has become essential for achieving high-performance n- and p-type devices, as well as significantly reducing contact resistance (R_C). In contrast, two-dimensional (2D) semiconductors have mainly relied on metal work-function engineering to lower R_C. While this approach has proven successful for n-type 2D FETs due to the natural tendency of the metal Fermi level to align near the conduction band edge, it has been challenging to achieve the same for p-type 2D FETs. To address this, we demonstrate that degenerate p-type doping can be accomplished in few-layer (>3) MoSe2 and WSe2 through substitutional doping of transition metal with V, Nb, and Ta. However, this substitutional doping leads to weakened electrostatic gate control, resulting in a poor on/off current ratio in multilayer p-type 2D FETs. Interestingly, at the monolayer limit, the doping effectiveness is significantly reduced due to strong quantum confinement effects, thereby restoring the electrostatic gate control. Based on this observation, we designed a FET structure where the channel is constructed using monolayer 2D material, while the contact regions consist of degenerately doped multilayers, allowing us to achieve both low R_C and high on/off current ratio. This doping and device design strategy is equally applicable for n-type FETs and can also redirect the large-area synthesis approach, emphasizing the production of doped multilayers to advance 2D FET technology.