bluuebunny/crossref_metadata_2025_split huggingface dataset:
Negative effects of urbanization on plants: A global meta‐analysis
Authors: Hou Yuchen , Li Junsheng , Li Guo , Qi Wei 
Published: April 2023

AbstractUnderstanding the response of plant diversity to urbanization is essential for conserving urban biodiversity. In this paper, a meta‐analysis of 34 articles and 163 observations regarding the impact of urbanization on plant diversity was conducted. The results revealed that urbanization had marked negative effects on plants. Urbanization had positive effects on introduced species and negative effects on native species. In the subgroup analysis, we found that trees responded better to the effect of urbanization than herbs and shrubs. There was no evidence that urban size, population density, nighttime light, and GDP per capita had moderating effects on plant richness. Based on meta‐regression analyses, native species in urban areas were less affected by urbanization at lower latitudes. Overall, urbanization had a marginally negative effect on plant abundance. The effects of urbanization on plant diversity during different stages of urban development were inconsistent. Our research shows that the suburbs play a crucial role in the urbanization gradient; there, plants survive with high species richness.
Monitoring the courtship flight trajectory of Latham's snipe (Gallinago hardwickii) using microphone arrays
Authors: Matsubayashi Shiho , Osaka Hideki , Suzuki Reiji , Nakadai Kazuhiro , Okuno Hiroshi G. 
Published: April 2023

AbstractThis study is the first to quantitatively measure the courtship display flights of Latham's snipe (Gallinago hardwickii), which is a “near threatened” species as of 2022 (IUCN red list of threatened species). By using a 16‐channel microphone array and 8‐channel microphone arrays, we localized the fine‐scale movements of courtship flights of one male performing at high altitude and high speed, and we estimated the direction from which each sound arrived using robot audition. Preliminary analyses of the azimuthal and elevation angles of the courtship flights partially revealed a fine‐scale flight trajectory. First, a male Latham's snipe gradually gained altitude while vocalizing sharp and harsh repeating calls, until it reached the flight peak altitude, then dove down while producing winnowing sound to the ground along the wetland zones without tall vegetation. This observation method is methodologically useful to establish a better understanding of Latham's snipe courtship flight site selection. Furthermore, this method can be extended to investigate other rare nocturnal or crepuscular birds that are too timid to risk ringing or tagging.
Niches of three sympatric montane ground‐dwelling squirrels: Relative importance of climate, topography, and landcover
Authors: Rossi Aviva J. , Klinger Robert C. , Hellwig Elise C. , Van Vuren Dirk H. 
Published: April 2023

AbstractSpecies with different ecological niches will likely exhibit distinct responses to a changing environment. Differences in the magnitude of niche specialization may also indicate which species may be more vulnerable to environmental change, as many life‐history characteristics are known to affect climate change vulnerability. We characterized the niche space of three sympatric high‐elevation ground‐dwelling squirrels, yellow‐bellied marmot (Marmota flaviventer), Belding's ground squirrel (Urocitellus beldingi), and golden‐mantled ground squirrel (Callospermophilus lateralis), in the alpine and upper subalpine regions of the Sierra Nevada in California. We used 5879 observations of individual squirrels, collected from 4 years (2009–2012) of transect survey data, to quantify which ecogeographical variable types (climate, topography, or landcover) were most important in defining the niche of each species. We conducted Ecological Niche Factor Analysis to quantify the niche and generate indices of “marginality” (magnitude of selection) and “specialization” (narrowness of niche space). All three species demonstrated differential use of niche space when compared to the available niche space. Moreover, the relative importance of the variables shaping the niche differed among these species. For example, the presence of meadows was important in defining the niche for U. beldingi and M. flaviventer, but the presence of conifers was important to C. lateralis. Precipitation was important in defining the niche for all three species, positively so for U. beldingi, and negatively for the other two species. The niche breadth of these three species was also positively associated with geographic range size. Mammals in high‐elevation mountain systems often are perceived as vulnerable to climate shifts, but our results underscore the importance of also including non‐climate‐based factors in defining the niche. The overall magnitude of niche selection for all three species was driven by a combination of topographic, climatic, and landcover factors; thus, efforts to forecast areas where these species can persist in the future need to evaluate from more than just a climatic perspective.
A COmplex PRoportional ASsessment and Gray Relational Analysis methodology hybrid optimization of compression ignition engine distinctiveness fuelled by dual feed stock pyrolysis of Annona squamosa seed particles and Aegle marmelos pressed seed cake pyrolytic liquid‐diesel opus
Authors: Raju Sasikumar , Paramasivam Baranitharan 
Published: April 2023

AbstractThe deficiency of fossil fuel resources, amplifying fuel price and its related environmental anxieties grasped great attention for finding an alternative fuel. Such alternative options can be fuels obtained from agricultural residues, plants, and wastes. The present research emphases on complex proportional assessment (COPRAS) and gray relational analysis (GRA) modeling of a diesel engine fuelled by Annona squamosa (AS) and Aegle marmelos (AM) co‐pyrolysis oil/diesel binary opus as an engine fuel to optimize the engine characteristics. Co‐pyrolysis oil is obtained from AS+AM feedstock at pyrolysis temperature of 500°C. To obtain engine data for training and testing the proposed COPRAS and GRA models were adopted for the engine control factors such as engine load (W) and compression ratio (CR) in a test engine rig through experimentation and hybrid optimization technics. From the engine output responses reveals that F2080 opus delivers an augmented brake thermal efficiency (22.01%) than diesel (21.56%) at peak load. Subsequently, F2080 fuel emits substantial lessening of CO (11.88%) and HC (5.64%) emissions as compared to diesel (F0). Based on the results, it is conclude that F2080 blend at CR of 17.5 and 100% load was delivered the greater engine distinctiveness through optimization outcomes and experimental evaluation compared to F0.
Tomato flu 2022 outbreak in India: Issues, challenges, and possible solutions
Authors: Adesola Ridwan Olamilekan , Idris Ibrahim , Opuni Emmanuel , D'Souza Joanna Nicole 
Published: April 2023

AbstractBackground and AimsThe outbreak of Tomato flu in India has affected the children making the parents tremble in worry and pain. The outbreak of this disease first occurred in India affecting young children below 5 years of age, thereby causing a threat to the country, neighboring countries, and the rest of the world—although no death is yet recorded. The aim of this research is to discuss the issues, challenges, and possible solutions associated with 2022 Tomato flu outbreaks in India.ResultsTomato flu is caused by Coxsackievirus A16 as confirmed in the United Kingdom. The health authorities are currently monitoring the spread of the virus and trying to understand it to develop strategies to contain it. But they are left with some challenges relating to the health system, surveillance, and adherence to preventive protocols among others.ConclusionTo prevent the spread of Tomato flu to other neighboring countries like China, Bangladesh, Pakistan, Sri Lanka, Myanmar, Afghanistan, Bhutan, Nepal, and the Maldives, the Indian Government must provide adequate public health control measures to contain the disease in children. Various recommendations have been given below.
Cytotoxic effects of psychoactive isobutyrylfentanyl and its halogenated derivatives on isolated rat hepatocytes
Authors: Nakagawa Yoshio , Suzuki Jin , Suzuki Toshinari , Takahashi Hideyo , Makino Kosho , Ono Yasushi , Sakamoto Miho , Inomata Akiko 
Published: April 2023

AbstractThe novel and numerous psychoactive compounds derived from the analgesic prescription drug N‐phenyl‐N‐[1‐(2‐phenylethyl)piperidin‐4‐yl]propanamide (fentanyl) have been illegally abused as recreational drugs and caused numerous fatalities. Because some psychoactive/psychotropic drugs are known to be hepatotoxic in humans and experimental animals, the cytotoxic effects and mechanisms of 4‐fluoroisobutyrylfentanyl (4F‐iBF), 4‐chloroisobutyrylfentanyl (4Cl‐iBF), and the parent compound isobutyrylfentanyl (iBF) were studied in freshly isolated rat hepatocytes. 4F‐iBF caused not only concentration (0–2.0 mM)‐ and time (0–3 h)‐dependent cell death accompanied by the depletion of cellular ATP and reduced glutathione (GSH) and protein thiol levels but also the accumulation of oxidized glutathione. Of these fentanyls examined, 4Cl‐iBF/4F‐iBF‐induced cytotoxicity with the loss of mitochondrial membrane potential at concentrations of 0.5 and 1.0 mM and the production of reactive oxygen species (ROS) at 0.5 mM were greater than those induced by iBF. The pretreatment of hepatocytes with N‐acetyl‐l‐cysteine as a precursor of cellular GSH ameliorated, at least in part, cytotoxicity accompanied by insufficient ATP levels, the loss of mitochondrial membrane potential, and generation of ROS caused by 4Cl‐iBF/4F‐iBF, whereas pretreatment with diethyl maleate as a GSH depletor enhanced fentanyl‐induced cytotoxicity accompanied by the rapid loss of cellular GSH. Taken collectively, these results indicate that the onset of cytotoxic effects caused by these fentanyls is partially attributable to cellular energy stress as well as oxidative stress.
“Inside” versus “outside” trends in consumer research
Authors: Camilleri Edwin , Garg Nitika , Miah Shah Jahan 
Published: April 2023

AbstractGiven its multi‐faceted nature, consumer research has evinced interest from scholars both within and outside the marketing domain, resulting in ongoing knowledge contributions from a diverse range of disciplines. We conduct a comprehensive review and comparison across both marketing (“inside”) and non‐marketing (“outside”) disciplines to identify which topics are most and least focused on within each disciplinary domain and which are emerging as the most impactful. We also identify which of the marketing (FT50) journals are at the forefront of cutting‐edge research and demonstrate their contributions to the progression of the most impactful topics in the field. Based on our findings, we identify key gaps and under‐researched areas of substantive interest, highlight impactful emerging topics in non‐marketing journals where marketing could offer unique perspectives, and provide concrete suggestions and directions to further progress and stimulate consumer research.
Sarcopenia and cardiovascular diseases: A systematic review and meta‐analysis
Authors: Zuo Xinrong , Li Xuehong , Tang Kuo , Zhao Rui , Wu Minming , Wang Yang , Li Tao 
Published: April 2023

AbstractSarcopenia is an age‐related disease and is often accompanied by other diseases. Now, many studies have shown that cardiovascular diseases (CVDs) may raise the incidence rate of sarcopenia. Therefore, the purpose of this study was to conduct a systematic review and meta‐analysis to investigate the prevalence of sarcopenia in patients with CVDs compared with the general population, defined as relatively healthy non‐hospitalized subjects. The databases of PubMed, Embase, Medline and Web of Science were searched for eligible studies published up to 12 November 2022. Two assessment tools were used to evaluate study quality and the risk of bias. Statistical analysis was conducted using STATA 14.0 and R Version 4.1.2. Thirty‐eight out of the 89 629 articles retrieved were included in our review. The prevalence of sarcopenia ranged from 10.1% to 68.9% in patients with CVDs, and the pooled prevalence was 35% (95% confidence interval [95% CI]: 28–42%). The pooled prevalence of sarcopenia was 32% (95% CI: 23–41%) in patients with chronic heart failure (CHF), 61% (95% CI: 49–72%) in patients with acute decompensated heart failure (ADHF), 43% (95% CI: 2–85%) in patients with coronary artery disease, 30% (95% CI: 25–35%) in patients with cardiac arrhythmia (CA), 35% (95% CI: 10–59%) in patients with congenital heart disease and 12% (95% CI: 7–17%) in patients with unclassed CVDs. However, in the general population, the prevalence of sarcopenia varied from 2.9% to 28.6% and the pooled prevalence was 13% (95% CI: 9–17%), suggesting that the prevalence of sarcopenia in patients with CVDs was about twice compared with the general population. The prevalence of sarcopenia was significantly higher only in patients with ADHF, CHF and CA compared with the general population. There is a positive correlation between CVDs and sarcopenia. The prevalence of sarcopenia is higher in patients with CVDs than that in the general population. With global aging, sarcopenia has brought a heavy burden to individuals and society. Therefore, it is important to identify the populations with high‐risk or probable sarcopenia in order to do an early intervention, such as exercise, to counteract or slow down the progress of sarcopenia.
Tobacco use in Crohn's disease patients and association with disease outcomes in the United States Medicaid population, 2010–2019
Authors: Jasper Ryan A. , Chen Po‐Hung , Patel Reeha , Joseph Shelly , Miller Steven D. , Hutfless Susan 
Published: April 2023

AbstractBackground and AimTo identify demographic factors associated with tobacco use in Crohn's disease (CD) patients in the US Medicaid population and examine how tobacco use affects disease outcomes.MethodsWe included Medicaid‐eligible patients who had ≥1 ICD code for CD, and 1 year of eligibility before and after the initial encounter. We used ICD codes to identify tobacco use with respect to the time of diagnosis and used logistic regression to identify the association between age, sex, and race with tobacco use at any point before diagnosis and after diagnosis, and determine the association of tobacco use before and after diagnosis on disease outcomes.ResultsWe identified 98 176 eligible patients; 74.5% had no documented use of tobacco and 25.5% used tobacco at some point; 21.1% had used tobacco before their CD diagnosis and 11.8% had used tobacco after diagnosis. The population that used tobacco had a higher proportion of women, those who were White, non‐Hispanic, and those in their middle ages (21–60) than the group that did not use tobacco. Tobacco use before diagnosis resulted in higher risk of hospitalization and surgery (OR: 1.85 and 1.36, respectively).ConclusionWithin the CD Medicaid population, tobacco use is more common in women than men, which differs from the general population, which is possibly a result of using diagnostic codes rather than survey data. Smoking cessation efforts should especially be directed at younger people who are at risk for CD, due to increased risk for more adverse outcomes among those who use tobacco before diagnosis.
Clinical and laboratory characteristics of patients with symptomatic secondary immunodeficiency following the treatment of haematological malignancies
Authors: Shields Adrian M. , Faustini Sian E. , Young Siobhan , Terjesen Sarah , McCarthy Nicholas I. , Anderson Rachel L. , Drayson Mark T. , Richter Alex G. 
Published: April 2023

AbstractSecondary immunodeficiency (SID), manifesting as increased susceptibility to infection, is an emergent clinical problem in haematoncology. Management of SID includes vaccination, prophylactic antibiotics (pAbx) and immunoglobulin replacement therapy (IgRT). We report clinical and laboratory parameters of 75 individuals, treated for haematological malignancy, who were referred for immunological assessment due to recurrent infections. Forty‐five were managed with pAbx while thirty required IgRT after failing to improve on pAbx. Individuals requiring IgRT had significantly more bacterial, viral and fungal infections resulting in hospitalization at least 5 years after their original haemato‐oncological diagnosis. Following immunological assessment and intervention, a 4.39‐fold reduction in the frequency of hospital admissions to treat infection was observed in the IgRT cohort and a 2.30‐fold reduction in the pAbx cohort. Significant reductions in outpatient antibiotic use were also observed in both cohorts following immunology input. Patients requiring IgRT were more hypogammaglobulinaemic and had lower titres of pathogen‐specific antibodies and smaller memory B cell populations than those requiring pAbx. Test vaccination with pneumococcal conjugate vaccine discriminated poorly between the two groups. Patients requiring IgRT could be distinguished by combining wider pathogen‐specific serology with a frequency of hospital admissions for infection. If validated in larger cohorts, this approach may circumvent the need for test vaccination and enhance patient selection for IgRT.
Physical training and high‐protein diet improved muscle strength, parent‐reported fatigue, and physical quality of life in children with Pompe disease
Authors: Scheffers L. E. , Somers O. C. , Dulfer K. , Dieleman G. C. , Walet S. , van der Giessen L. J. , van der Ploeg A. T. , van den Hout J. M. P. , van den Berg L. E. ,   the exercise team
Published: April 2023

AbstractExercise has proven to be an effective adjuvant treatment to enzyme replacement therapy (ERT) in mildly affected adult Pompe patients. The aim of this study was to investigate the effects of a 12‐week tailored lifestyle intervention, consisting of physical training and a high protein diet (2 grams/kg), in children with Pompe disease. This randomized controlled semi‐crossover trial investigated the effects of a lifestyle intervention on the primary outcome: exercise capacity. Secondary outcomes were: muscle strength, core stability, motor function, physical activity levels, quality of life, fatigue, fear of exercise, caloric intake, energy balance, body composition, and safety. Fourteen Pompe patients with a median age of 10.6 [IQR: 7.2–14.5], of whom six classic infantile patients, participated in the lifestyle intervention. At baseline, patients had a lower exercise capacity compared to healthy peers (median 70.3% [IQR: 54.8%–98.6%] of predicted). After the intervention, absolute Peak VO2 improved significantly (1279 mL/min [1012.5–2006] vs. 1352 mL/min [1101.5–2069], p = 0.039), but not compared to the control period. Muscle strength of the hip flexors, hip abductors, elbow extensors, neck extensors, knee extensors, and core stability improved significantly compared to the control period. Children reported a significant increase on the change in health domain of quality of life, parents reported significantly better scores on the quality of life domains: physical functioning, change in health, family cohesion, and fatigue. A 12‐week tailored lifestyle intervention for children with Pompe disease seemed safe and led to improvements in muscle strength, core stability, quality of life, and parent‐reported fatigue. Pompe patients with a stable disease trajectory seemed to benefit the most from the intervention.
Regional abnormalities of spontaneous brain activity in migraine: A coordinate‐based meta‐analysis
Authors: Wen Jian‐Jie , Gao Yan‐Yan , Li Meng‐Ting , Hu Su , Zhao Meng‐Qi , Su Chang , Wang Qing , Xi Hong‐Yu , Zhan Lin‐Lin , Lv Ya‐Ting , Antwi Collins Opoku , Ren Jun , Jia Xi‐Ze 
Published: April 2023

AbstractMany resting‐state functional magnetic resonance imaging (rs‐fMRI) studies have explored abnormal regional spontaneous brain activity in migraine. However, these results are inconsistent. To identify the consistent regions with abnormal neural activity, we meta‐analyzed these studies. We gathered whole‐brain rs‐fMRI studies measuring differences in the amplitude of low‐frequency fluctuations (ALFF), fractional ALFF (fALFF), or regional homogeneity (ReHo) methods. Then, we performed a voxel‐wise meta‐analysis to identify consistent abnormal neural activity in migraine by anisotropic effect size seed‐based d mapping (AES‐SDM). To confirm the AES‐SDM meta‐analysis results, we conducted two meta‐analyses: activation likelihood estimation (ALE) and multi‐level kernel density analysis (MKDA). We found that migraine showed increased regional neural activities in the bilateral postcentral gyrus (PoCG), left hippocampus (HIP.L), right pons, left superior frontal gyrus (SFG.L), triangular part of right inferior frontal gyrus (IFGtriang.R), right middle frontal gyrus (MFG.R), and left precentral gyrus (PreCG.L) and decreased regional intrinsic brain activities were exhibited in the right angular gyrus (ANG.R), left superior occipital gyrus (SOG.L), right lingual gyrus (LING.R). Moreover, the meta‐analysis of ALE further validated the abnormal neural activities in the PoCG, right pons, ANG.R, and HIP. Meta‐regression demonstrated that headache intensity was positively associated with the abnormal activities in the HIP.L, ANG.R, and LING.R. These findings suggest that migraine is associated with abnormal spontaneous brain activities of some pain‐related regions, which may contribute to a deeper understanding of the neural mechanism of migraine.
High frequency monitoring of feeding activity in benthic suspension feeders
Authors: Agüera Antonio , Strohmeier Tore , Krogness Cathinka , Strand Øivind 
Published: April 2023

AbstractSuspension feeders ecosystem role and services are mainly driven by their efficiency in clearing particles from the water column. As such there is an interest on suspension feeders feeding activity and how they interact with the ecosystem. Advancing research on feeding response requires experimental designs where individuals can be exposed to continuously changing environments and where feeding activity can be monitored at a high frequency and at different time scales. However, interindividual variability or temporal dynamics in feeding behaviors cannot be investigated properly by the methods commonly used. There are several methods to monitor feeding activity of suspension feeders. Among them, the flow‐through method allows individuals to be exposed to changing conditions. As with the other existing methods, the flow‐through method is labor intensive limiting both the number of individuals that could be observed simultaneously and the time resolution of observations. The flow‐through method is constrained by the need to measure the flow rate through the chambers and to take samples to determine particle concentration in the water. In this work, we automated the standard flow‐through method using microcontroller based prototyping. The result is a methodological approach that continuously monitor feeding at high frequency and on a larger number of individuals while reducing handling and measurement errors. As such, this method brings a solution to the current limitations when studying suspension feeders feeding behaviors. This work provides the description and assessment of the automated set‐up, which is an end to end solution that can readily assembled and configured.
Innovation performance feedback and patent acquisition from the market: A behavioral perspective
Authors: Lee Jongseon , Kim Nami 
Published: April 2023

AbstractFirms can facilitate external technology sourcing through transactions from the market. This study focuses on determinants of demand‐side motivation to join the technology transactions market. Drawing on the behavioral theory of the firm, we suggest that one of such determinants is the desire of a firm, whose innovation performance is below its aspiration level, to find a technology that will help improve its performance. Furthermore, we suggest that inconsistent feedback on its multiple goals and the type of R&D structure as moderating factors that can influence a firm's acquisition of technology in response to its poor performance.