bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Pengetahuan dan Sikap tentang Anemia pada Ibu dan Remaja terhadap Kecukupan Konsumsi Zat Besi
Authors: Agestika Lina , Pratiwi Vini Asri 
Published: September 2023

Anemia in adolescent girls aged 15-17 years is one of the main health problems in developing countries, especially in Indonesia. Knowledge and attitudes of adolescents and their mothers about anemia can affect their iron consumption. This study aims to analyze the relationship between the knowledge and attitudes of students and mothers about anemia with iron consumption in female adolescent. This is a cross-sectional study with a random sampling technique. Respondents were 67 pairs of female adolescents and their mothers. Collecting data in this study by filling out a knowledge and attitude questionnaire about anemia, and iron consumption was measured by food recall 2 x 24 hours. Data analysis in this study used the chi-square test. The results showed that adolescents with insufficient iron intake were 34.2%. 47,8% of adolescent girls and 44,8% of mothers have less knowledge about anemia. Meanwhile, the attitudes of female adolescents and mothers towards anemia were not good at 19.4% and 38.8%. Statistical analysis revealed that female adolescents with high knowledge (p-value: 0.000) and positive attitude (0.021) were more likely to consume high iron intake. Mothers' knowledge about anemia also showed the same result (p-value: 0.039), but not with their attitude (p-value = 0.969). In conclusion, female adolescents knowledge and attitudes in term of anemia are important in maintaining adequate iron intake.
PENERAPAN TEKNOLOGI AUGMENTED REALITY PADA E-CATALOGUE KEMASAN DI CV. ZONA GRAFIKA MULTIKARYA
Authors: Siti Fatimatul Azizah  , Ronny Makhfuddin Akbar  , Mimin Fatchiyatur Rohmah  
Published: September 2023

Kemajuan dan perkembangan teknologi di bidang industri pada era ini khususnya pada bidang pemasaran dan promosi mendorong semakin banyaknya perusahaan berusaha lebih keras untuk membuat kreativitas dan inovasi yang lebih baru sebagai media promosi. Augmented Reality merupakan teknologi yang menggabungkan antara objek gambar dan menjadikannya objek 3 dimensi dengan menggunakan marker sehingga dapat diaplikasikan pada katalog sebagai petunjuk informasi produk untuk customer yang akan melakukan pembelian. Aplikasi Augmented Reality tersebut dapat menampilkan objek 3 dimensi sekaligus informasi dari berbagai jenis kemasan seperti standing pouch, center seal, can, dus, bag, bottle dan cup. Diharapkan dengan adanya aplikasi ini dapat mengedukasi customer mengenai berbagai jenis kemasan dengan berbagai spesifikasinya serta menarik minat customer untuk membeli berbagai produk packaging yang ditawarkan melalui media promosi E-Catalogue. Berdasarkan hasil pengujian black box menyatakan bahwa system aplikasi berjalan secara baik sesuai dengan yang diharapkan.
ANALISIS MINAT BELAJAR MATERI PECAHAN DENGAN MEDIA KONKRET DI KELAS II SDN KARANGANYAR GUNUNG 02
Authors: Dian Nurul Laily  , Mei Fita Untari  , Iin Purnamasari  
Published: September 2023

ABSTRAK
Matematika merupakan salah satu mata pelajaran yang membuat siswa terbiasa untuk berfikir secara sistematis, ilmiah dan kritis. Dalam pembelajaran Matematika, siswa seringkali mengalami kesulitan baik dalam pemahaman bahasa yang kurang ataupun kesulitan dalam berhitung sehingga minat belajar matematika pada siswa menjadi berkurang. Dengan penggunaan media pembelajaran konkret, diharapkan dapat memberikan wujud nyata dalam materi pembelajaran dan menumbuhkan perhatian dan minat belajar pada siswa. Penelitian ini bertujuan untuk mendeskripsikan minat belajar siswa kelas 2 pada mata pelajaran matematika materi pecahan dengan menggunakan media pembelajaran konkrit di SDN Karanganyar Gunung 02. Metode yang digunakan dalam penelitian ini adalah penelitian kualitatif. Teknik pengumpulan data pada penelitian ini berupa observasi, angket, dan dokumentasi. Hasil dari penelitian menunjukkan bahwa melalui media pembelajaran konkret, minat belajar siswa pada mata pelajaran Matematika materi pecahan terlihat sangat baik. Simpulan dari penelitian ini yaitu adanya minat belajar yang sangat baik pada siswa kelas 2 dalam mata pelajaran Matematika pada materi pecahan melalui media konkret di SDN Karanganyar Gunung 02 Kota Semarang.
Kata Kunci : Minat Belajar, Materi Pecahan, Media Konkret
B Cells from Aged Mice Do Not Have Intrinsic Defects in Affinity Maturation in Response to Immunization
Authors: Lee Jia Le , Innocentin Silvia , Silva-Cayetano Alyssa , Guillaume Stephane M , Linterman Michelle A 
Published: September 2023

Abstract
Affinity maturation, the progressive increase in serum Ab affinity after vaccination, is an essential process that contributes to an effective humoral response against vaccines and infections. Germinal centers are key for affinity maturation, because they are where B cells undergo somatic hypermutation of their Ig genes in the dark zone before going through positive selection in the light zone via interactions with T follicular helper cells and follicular dendritic cells. In aged mice, affinity maturation has been shown to be impaired after immunization, but whether B cell–intrinsic factors contribute to this defect remains unclear. In this study, we show that B cells from aged BCR transgenic mice are able to become germinal center B cells, which are capable of receiving positive selection signals to a similar extent as B cells from young adult mice. Consistent with this, aging also does not impact the ability of B cells to undergo somatic hypermutation and acquire affinity-enhancing mutations. By contrast, transfer of B cells from young adult BCR mice into aged recipients resulted in the impaired acquisition of affinity-enhancing mutations, demonstrating that the aged microenvironment causes altered affinity maturation.
Dose-Specific Intratumoral GM-CSF Modulates Breast Tumor Oxygenation and Antitumor Immunity
Authors: Mihalik Nicole E , Steinberger Kayla J , Stevens Alyson M , Bobko Andrey A , Hoblitzell E Hannah , Tseytlin Oxana , Akhter Halima , Dziadowicz Sebastian A , Wang Lei , O’Connell Ryan C , Monaghan Kelly L , Hu Gangqing , Mo Xiaokui , Khramtsov Valery V , Tseytlin Mark , Driesschaert Benoit , Wan Edwin C K , Eubank Timothy D 
Published: September 2023

Abstract
GM-CSF has been employed as an adjuvant to cancer immunotherapy with mixed results based on dosage. We previously showed that GM-CSF regulated tumor angiogenesis by stimulating soluble vascular endothelial growth factor (VEGF) receptor-1 from monocytes/macrophages in a dose-dependent manner that neutralized free VEGF, and intratumoral injections of high-dose GM-CSF ablated blood vessels and worsened hypoxia in orthotopic polyoma middle T Ag (PyMT) triple-negative breast cancer (TNBC). In this study, we assessed both immunoregulatory and oxygen-regulatory components of low-dose versus high-dose GM-CSF to compare effects on tumor oxygen, vasculature, and antitumor immunity. We performed intratumoral injections of low-dose GM-CSF or saline controls for 3 wk in FVB/N PyMT TNBC. Low-dose GM-CSF uniquely reduced tumor hypoxia and normalized tumor vasculature by increasing NG2+ pericyte coverage on CD31+ endothelial cells. Priming of “cold,” anti-PD1–resistant PyMT tumors with low-dose GM-CSF (hypoxia reduced) sensitized tumors to anti-PD1, whereas high-dose GM-CSF (hypoxia exacerbated) did not. Low-dose GM-CSF reduced hypoxic and inflammatory tumor-associated macrophage (TAM) transcriptional profiles; however, no phenotypic modulation of TAMs or tumor-infiltrating lymphocytes were observed by flow cytometry. In contrast, high-dose GM-CSF priming increased infiltration of TAMs lacking the MHC class IIhi phenotype or immunostimulatory marker expression, indicating an immunosuppressive phenotype under hypoxia. However, in anti-PD1 (programmed cell death 1)–susceptible BALB/c 4T1 tumors (considered hot versus PyMT), high-dose GM-CSF increased MHC class IIhi TAMs and immunostimulatory molecules, suggesting disparate effects of high-dose GM-CSF across PyMT versus 4T1 TNBC models. Our data demonstrate a (to our knowledge) novel role for low-dose GM-CSF in reducing tumor hypoxia for synergy with anti-PD1 and highlight why dosage and setting of GM-CSF in cancer immunotherapy regimens require careful consideration.
Relationship of Heterologous Virus Responses and Outcomes in Hospitalized COVID-19 Patients
Authors: Rosenberg-Hasson Yael , Holmes Tyson H , Diray-Arce Joann , Chen Jing , Kellogg Ryan , Snyder Michael , Becker Patrice M , Ozonoff Al , Rouphael Nadine , Reed Elaine F ,   IMPACC Network, Maecker Holden T 
Published: September 2023

Abstract
The clinical trajectory of COVID-19 may be influenced by previous responses to heterologous viruses. We examined the relationship of Abs against different viruses to clinical trajectory groups from the National Institutes of Health IMPACC (Immunophenotyping Assessment in a COVID-19 Cohort) study of hospitalized COVID-19 patients. Whereas initial Ab titers to SARS-CoV-2 tended to be higher with increasing severity (excluding fatal disease), those to seasonal coronaviruses trended in the opposite direction. Initial Ab titers to influenza and parainfluenza viruses also tended to be lower with increasing severity. However, no significant relationship was observed for Abs to other viruses, including measles, CMV, EBV, and respiratory syncytial virus. We hypothesize that some individuals may produce lower or less durable Ab responses to respiratory viruses generally (reflected in lower baseline titers in our study), and that this may carry over into poorer outcomes for COVID-19 (despite high initial SARS-CoV-2 titers). We further looked at longitudinal changes in Ab responses to heterologous viruses, but found little change during the course of acute COVID-19 infection. We saw significant trends with age for Ab levels to many of these viruses, but no difference in longitudinal SARS-CoV-2 titers for those with high versus low seasonal coronavirus titers. We detected no difference in longitudinal SARS-CoV-2 titers for CMV seropositive versus seronegative patients, although there was an overrepresentation of CMV seropositives among the IMPACC cohort, compared with expected frequencies in the United States population. Our results both reinforce findings from other studies and suggest (to our knowledge) new relationships between the response to SARS-CoV-2 and Abs to heterologous viruses.
ON LITERARY AND FOLKLORE TRANSFORMATION IN THE NOVEL “A HUNDRED AND FIRST PASS” BY I. MASHBASH
Authors: ТХАГАЗИТОВ Ю.М. , ХАВЖОКОВА Л.Б. 
Published: September 2023

Авторами статьи предлагается концепция осмысления/переосмысления «малоформатного» романа «Сто первый перевал» Исхака Машбаша как редкого и оригинального явления в северокавказской литературе. Актуальность заявленной проблемы определяется диалектикой соотношения «своего» и «чужого» (национального и общечеловеческого), уровней взаимообусловленности этнически-циклического и «эсхатологического» типов сознания, актуализированных противоречиво глобализирующимся миром. Научная новизна исследования состоит в том, что роман И. Машбаша исследуется в новаторском аспекте, с акцентированием внимания на отчетливо проявляющейся в нем литературно-фольклорной трансформации. Отмечается заслуга двух ключевых писателей – Алима Кешокова и Исхака Машбаша, сыгравших заметную роль в становлении и эволюции национальной романистики: выявляются типологические схождения и различия их романов «Сломанная подкова» и «Сто первый перевал». Главным объектом исследовательского внимания является второй из указанных романов. В статье применен ряд научных методов, в числе главных – анализ, описание, сравнительно-исторический и герменевтический методы. Полученные результаты могут быть использованы при изучении истории адыгской литературы, и в более обширном плане – литературы народов Северного Кавказа и Российской Федерации, а также при составлении спецкурсов и написании квалификационных и другого рода исследовательских работ.
The authors of the article propose the concept of understanding/rethinking the "small-format" novel "A hundred and first pass" by Iskhak Mashbash as a rare and original phenomenon in the North Caucasian literature. The urgency of the stated problem is determined by the dialectic of the correlation of "one's own" and "alien" (national and universal), the levels of interdependence of ethnic-cyclic and "eschatological" types of consciousness, actualized by the contradictory globalizing world. The scientific novelty of the study lies in the fact that the novel by I. Mashbash is studied in an innovative aspect, with an emphasis on the literary and folklore transformation that is clearly manifested in it. The merit of two key writers – Alim Keshokov and Iskhak Mashbash, who played a significant role in the formation and evolution of national romance is noted: typological similarities and differences between their novels "The Broken Horseshoe" and "A hundred and first pass" are revealed. The main object of research attention is the second of these novels. The article uses a number of scientific methods, among the main ones are analysis, description, comparative historical and hermeneutical methods. The results obtained can be used in the study of the history of the Adyghe literature, and in a broader sense – the literature of the peoples of the North Caucasus and the Russian Federation, as well as in the preparation of special courses and writing qualifying and other kinds of research papers.
Pengaruh Gaya Kepemimpinan dan Motivasi Kerja Terhadap Kinerja Karyawan Pada PT. Daehan Global
Authors: Dumadi Dumadi , Ayu Ainunnisa  , Khojin Nur , Harini Dwi 
Published: September 2023

Penelitian ini bertujuan untuk mengetahui pengaruh gaya kepemimpinan dan motivasi kerja terhadap kinerja karyawan PT.Daehan-Global-Brebes.Data diperoleh dari penyebaran kuesioner kepada karyawan PT.Daehan Global di departemen cutting berjumlah 40 orang. Teknik analisis data yang digunakan dalam penelitian ini yaitu uji asumsi klasik. Analisis data menggunakan regresi linier berganda untuk memperoleh gambaran menyeluruh mengenai hubungan antara variabel. Hasil penelitian menunjukkan bahwa gaya kepemimpinan tidak berpengaruh terhadap kinerja karyawan dan motivasi kerja berpengaruh positif signifikan terhadap kinerja karyawan PT.Daehan Global. Berdasarkan analisis data persamaan regresi linier di peroleh sebagai berikut Y = 18.859 - 0,047X1 + 0,390X2. Pengujian Hipotesis menggunakan Uji t bahwa variabel gaya kepemimpinan tidak berpengaruh terhadap kinerja karyawan dan variabel motivasi kerja berpengaruh positif terhadap kinerja karyawan.Hasil penelitian secara simultan dengan menggunakan uji F,menunjukan bahwa dua variabel bebas ada yang tidak berpengaruh signifikan terhadap kinerja karyawan. Nilai R Square sebesar 0,203 yang dapat di artikan bahwa variabel gaya kepemimpinan (X1) dan motivasi kerja (X2) terhadap kinerja karyawan (Y) sebesar 20,3% sedangkan sisanya 70,7% di pengaruhi oleh variabel
PENGEMBANGAN KEDAI BESTE COFFEE
Authors: Kurniawan Akh Khotib , Qintari Yudith Vitarani Safira 
Published: September 2023

Pengembangan kedai kopi ‘’ BESTE COFFEE ‘’ Program Studi Ilmu dan Teknologi Pangan Fakultas Sains dan Teknologi di dalam lingkungan kampus sebagai ruang untuk baik musyawarah, berdiskusi maupun mengerjakan tugas baik dosen maupun mahasiswa di lingkungan kampus sambil menikmati kopi, tujuan dari pengembangan ini adalah mengetahui strategi yang akan dilakukan dalam pengembangan kedai ‘’BESTE COFFE’’ dilingkungan kampus, menggunakan metode analisis diantaranya pengembangan produk baru dan menggunakan analisis SWOT Strenght ( Kekuatan ), Weaknes ( Kelemahan), Opportunity (Peluang) dan Treast (Ancaman). Hasil dari pengembangan kedai ‘’BESTE COFFE’’ yaitu adanya produk baru , mengetahui SWOT dari pengembangan kedai. Perlunya sebuah strategi dalam mengembangkan sebuah usaha kopi agar dapat diterima di dalam lingkungan kampus.
Evaluación de enfermedad cardiovascular subclínica en pacientes con diabetes mellitus tipo 1
Authors: Altamira María , Álvarez Analía , Bringa Javier , Echegoyen Marisel , Lemos Patricia , Mosso G , Negri María Gabriela , Savina Mariela , Segura Gimena 
Published: September 2023

Introducción: pacientes con diabetes mellitus tipo 1 (DM1) poseen mayor riesgo de enfermedad cardiovascular (ECV). Existen estudios en los que se observó que en pacientes con DM1 la ECV aparece en edades más tempranas, comparado con la población general. La asociación de anomalías vasculares y aterosclerosis es muy frecuente en DM1, siendo la detección del engrosamiento de la íntima media carotidea un método útil para realizar el diagnóstico de enfermedad aterosclerótica subclínica.
Objetivos: realizar detección precoz de ECV subclínica, conocer si existe correlación directa entre la DM1 y diversos factores de riesgo a fin de instaurar medidas terapéuticas tempranas.
Riesgo cardiovascular del personal de un centro asistencial: ¿organización mundial de la salud o Framingham?
Authors: González Guillermo , Olivares Diego 
Published: September 2023

Introducción: la evolución de los determinantes de las enfermedades crónicas no transmisibles pronostica un aumento en su incidencia y prevalencia. Esto condicionaría mayor morbilidad y mortalidad generando una creciente necesidad de uso de recursos del sistema de salud. El Score de Framingham y las tablas de predicción de riesgo de la Organización Mundial de la Salud (OMS) permiten calcular el riesgo de sufrir un evento cardiovascular a 10 años.
Objetivos: calcular el riesgo cardiovascular según Score de Framingham y las tablas OMS en ambos casos con y sin empleo de laboratorio. Comparar las categorías de riesgo cardiovascular de Framingham y OMS, con y sin datos de laboratorio.
Pie diabético, posible marcador de riesgo de enfermedad cardiovascular en DM2
Authors: Altamira María , Álvarez Analía , Bringa Javier , Echegoyen Marisabel , Ferrada Pablo , Herrera Javier , Lemos Patricia , Negri María Gabriela , Segura Gimena , Segura Mariela , Torres Eduardo 
Published: September 2023

Introducción: mientras que el síndrome de pie diabético (SPD) se define como “una úlcera del pie y/o tobillo, asociado con neuropatía, isquemia e infección” (Organización Mundial de la Salud), se considera pie de riesgo a aquel con características que aumentan la probabilidad de desarrollar un SPD, presente en el 15% de diabéticos durante el curso de su enfermedad. Pinto et al. demostraron mayor prevalencia de factores de riesgo cardiovascular (FRCV), de marcadores subclínicos de enfermedad CV, eventos CV y cerebrovasculares previos y nuevos en pacientes con DM y complicaciones de pie (vs DM-pie sano).
Objetivos: evaluar la relación entre riesgo de pie y frecuencia de cardiopatía isquémica (CI) en pacientes diabéticos.
Diálogos críticos sobre o ensino de línguas adicionais: da sala de aula às políticas linguísticas
Authors: Farias Priscila , Da Silva Leonardo , Pimentel Siqueira Domingos Sávio 
Published: September 2023

Apresentação dos artigos do dossiê Um Olhar Crítico Para a Educação de Línguas Adicionais: Possibilidades Pedagógicas e Formativas, publicado no Volume 41, número 1, jan./mar., 2023, da revista Perspectiva.
Noisy band selection based on the integration of the Stacked-Autoencoder and Convolutional Neural Network approaches for hyperspectral data.
Authors: JIJÓN-PALMA Mario Ernesto , AMISSE Caisse , MACUÁCUA Jaime Carlos , CENTENO Jorge Antonio Silva 
Published: September 2023

The presence of noise on hyperspectral images causes degradation and hinders efficiency of processing for land cover classification. In this sense, removing noise or detecting noisy bands automatically on hyperspectral images becomes a challenge for research in remote sensing. To cope this problem, an integrated model (SAE-1DCNN) is presented in this study, based on Stacked-Autoencoders (SAE) and Convolutional Neural Networks (CNN) algorithms for the selection and exclusion of noisy bands. The proposed model employs convolutional layers to improve the performance of autoencoders focused on discriminating the training data by analyzing the hyperspectral signature of the pixel. Thus, in the SAE-1DCNN model, information can be compressed, and then redundant information can be detected and extracted by taking advantage of the efficiency of the deep architecture based on the convolutional and pooling layers. Hyperspectral data from the AVIRIS (Airborne Visible/Infrared Imaging Spectrometer) sensor were used to evaluate the performance of the proposed automatic method based on feature selection. The results showed effectiveness to identify noisy bands automatically, suggesting that the proposed methodology was found to be promising and can be an alternative to identify noisy bands within the scope of hyperspectral data pre-processing.
Keywords: noisy bands; feature selection; convolutional neural network; stacked-autoencoders; hyperspectral data
The Letter to the Philippians
Authors: Hansen G. Walter 
Published: September 2023

In this commentary G. Walter Hansen offers rich exposition of the text of Philippians as well as wisdom and maturity in its application. In so doing he emphasizes partnership — the social and corporate dimensions of community — in the progress of the gospel.
After a select bibliography, Hansen's introduction sets forth the historical setting of the church in Philippi, the nature and occasion of the letter, and a preview of two key themes — the gospel of Christ and the community in Christ. The commentary itself discusses Philippians in light of these themes, considering Paul's greetings, reports of gospel ministry, imperatives for citizens worthy of the gospel, recommendations of two Christ-like servants, and disclosures of his personal experience. Hansen's treatment as a whole is distinctive for the way it draws out and highlights the themes of partnership, citizenship, and friendship in Paul's Philippian letter.
VIOLENT CRIME AND SECURITY CHALLENGES: ‘POLICE-PUBLIC BLAME GAME’ IN GHANA
Authors: Halidu Musah  
Published: September 2023

Violent crime such as robbery, assault, murder, sexual and domestic violence, undermine the economic and social rights of the people and distorts society’s attempts to achieve a decent and dignified life for all. To reverse the situation, in Ghana, the police have been charged with the primary responsibility of maintaining domestic security. The emerging development in the country, however, has been the blame game between the police and the public in respect of the perceived failure in security governance for the citizenry. This study examined this blame game using Sawla-Tuna-Kalba District of Savannah Region as a case study. To be able to achieve the intended objective, 102 respondents were selected through both probability and non-probability sampling techniques in a convergent sequential mixed method design. Expert administered questionnaire and interviews were employed as the main methods of data collection. The study found that non-prosecution of criminals, bribery and corruption, police-criminal relationship, inadequate logistics and police personnel and stakeholders’ interference in security management, cumulatively were responsible for the low level of security administration in the study area. The study concluded that both the police and the public are responsible for the defective security architecture in the study community. Since crime impacts multiple facets of society in ways that the police and government may not be aware of until those interests are taken into consideration during project development and implementation, the study recommends a multi-sector collaboration involving the government, the police and the public to improve security governance in the area.
Keywords: Crime, Violence, Security, Police, Citizenry, Peace Architecture.