bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Etos Kerja dan Iklim Organisasi Terhadap Komitmen Organisasi Karyawan Divisi Sortation Perusahaan
Authors: Ghani Abdul , Susita Dewi , Suherman  
Published: April 2023

This study aims to: (1) Knowing the description of the work ethic, organizational climate, and organizational commitment of employees of the sorting division of PT A. (2) Analyzing the effect of work ethic on organizational commitment to employees of the sorting division of PT A. (3) Analyzing the influence of organizational climate on organizational commitment to employees of the sorting division of PT A. (4) Analyzing the effect of work ethic and organizational climate together on organizational commitment to employees of the sorting division of PT A. The type of data used is quantitative. The sample in this study was 122 people who were determined by the slovin formula. Collecting data using observation, interviews, and questionnaires. The data analysis technique used is multiple linear regression analysis using SPSS software version 25.0. Based on the analysis, it was found that work ethic has a positive and significant effect on organizational commitment, organizational climate has a positive and significant influence on organizational commitment, and work ethic and organizational climate together have a positive and significant influence on organizational commitment.

Penelitian ini bertujuan untuk : (1) Mengetahui deskripsi dari etos kerja, iklim organisasi, dan komitmen organisasi karyawan divisi sortation PT A. (2) Menganalisis pengaruh etos kerja terhadap komitmen organisasi pada karyawan divisi sortation PT A. (3) Menganalisis pengaruh iklim organisasi terhadap komitmen organisasi pada karyawan divisi sortation PT A. (4) Menganalisis pengaruh etos kerja dan iklim organisasi secara bersama-sama terhadap komitmen organisasi pada karyawan divisi sortation PT A. Jenis data yang digunakan adalah kuantitatif. Sampel pada penelitian ini sebanyak 122 orang yang ditentukan dengan rumus slovin. Pengumpulan data menggunakan observasi, wawancara, dan kuesioner. Teknik analisis data yang digunakan adalah analisis regresi linear berganda menggunakan bantuan software SPSS versi 25.0. Berdasarkan analisis ditemukan bahwa etos kerja memiliki pengaruh positif dan signifikan terhadap komitmen organisasi, iklim organisasi memiliki pengaruh positif dan signifikan terhadap komitmen organisasi, serta etos kerja dan iklim organisasi secara bersama-sama memiliki pengaruh positif dan signifikan terhadap komitmen organisasi.
The burden of unintended pregnancies among Indian adolescent girls in Bihar and Uttar Pradesh: findings from the UDAYA survey
Authors: Sharma Himani , Singh Shri Kant 
Published: April 2023

Abstract
Background: Unintended pregnancy severely affects the health and welfare of women and children, specifically if they are young and vulnerable. This study aims to determine the prevalence of unintended pregnancy and its determinants among young adolescent girls in Bihar and Uttar Pradesh. We believe the present study is unique as it examines the association between unintended pregnancy and sociodemographic factors among adolescent girls in two backward states of India from 2015-19.
Methods: The data for the present study is derived from the two-wave longitudinal survey "Understanding the lives of adolescents and young adults” (UDAYA) conducted in 2015-16 (Wave 1) and 2018-19 (Wave 2). Univariate, bivariate analysis along with logistic regression models were employed.
Results: The results revealed that 40.1 per cent of all currently pregnant adolescents reported their pregnancy as unintended (mistimed and unwanted) in Uttar Pradesh at Wave 1 of the survey, which decreased to 34.2 per cent at Wave 2. On the contrary, almost 99 per cent of all currently pregnant adolescents in Bihar reported their pregnancy as unintended at Wave 1, which decreased to 44.8 per cent at Wave 2. The sociodemographic factors like age, caste, religion, education, wealth, media and internet use, knowledge and effective contraception broadly impact unintended pregnancy in Bihar and Uttar Pradesh. The longitudinal results of the study revealed that residence, internet use, number of wanted children, heard about contraception and SATHIYA, use of contraception, side effects of contraception, and the confidence in getting contraceptives from ASHA/ANM did not appear significant predictors at Wave 1. However, they emerge significant over time (Wave 2).
Conclusions: Despite many recently launched policies for adolescents and the youth population, this study comprehended that the level of unintended pregnancies in Bihar and Uttar Pradesh stands worrisome. Therefore, adolescents need more comprehensive family planning services to improve their awareness and knowledge about family planning.
Aromatic annular carbon allotropes: cumulenic cyclo[10]carbon and Peierls-transition-intermediate cyclo[14]carbon
Authors: Sun Luye , Zheng Wei , Gao Wenze , Kang Faming , Zhao Mali , Xu Wei 
Published: April 2023

Abstract
Cyclo[n]carbon allotropes built from sp-hybridized carbon atoms have aroused substantial interests, but until now even their structures (i.e., polyynic or cumulenic) and stabilities (i.e., cyclic or linear) are still under debate. Due to their high reactivity, it is rather difficult to synthesize in condensed phase, which hampers further real-space characterizations. Recently, isolated cyclo[18]carbon (C18) and cyclo[16]carbon (C16) molecules were generated on the surface by atom manipulation, which allowed to identify the polyynic structure of C18 and C16. More interestingly, for the smaller cyclo[n]carbon, questions arise: is it still stable in cyclic form? If so, what is the structure? Here, we successfully produce two aromatic cyclocarbons, that is, cyclo[10]carbon (C10) and cyclo[14]carbon (C14), via tip-induced dehalogenation and followed by retro-Bergman reaction of fully chlorinated naphthalene (C10Cl8) and anthracene (C14Cl10) molecules, on a bilayer NaCl/Au(111) surface at 4.7 kelvin. The cumulenic structure of C10 and Peierls-transition intermediate of C14, different from the polyynic structure of C18 and C16, are revealed by bond-resolved atomic force microscopy. Our results demonstrate a universal synthetic strategy to generate aromatic cyclo[n]carbons on the surface, opening an avenue for characterizing a series of annular carbon allotropes for the structure and stability.
A target prediction method to inhibit the replication process of SARS-CoV-2 via metabolic differential analysis
Authors: Zheng Haoran , Qi Yupeng , Zhao Yanlong 
Published: April 2023

Abstract

The emergence and rapid spread of COVID-19 has had a tremendous impact on people's lives, and it is therefore necessary to study how to treat COVID-19. SARS-CoV-2 invades and reprograms human cells, altering the host cell metabolic system to favor its survival and replication, ultimately leading to disease onset. However, few studies have focused on inhibiting the replication process of SARS-CoV-2. In this paper, we present a novel method to inhibit SARS-CoV-2 replication. Our method reconstructs network models of the host cell metabolic systems altered by virus invasion and predicts candidate antiviral targets via metabolic differential analysis. We separately analyzed gene expression data from lung and non-lung host cells to perform target prediction. The results indicate that D-alanine is a key metabolite affecting SARS-CoV-2 replication. Our approach is general and applicable to existing viruses, offering new ideas for dealing with viral diseases.
The electron modulation effect on metal nanoclusters of Fe-N-C based bifunctional electrocatalysts
Authors: Chen Guanyu , Liu Yihao , Xue Shuyan , Liu Jiwei , You Wenbin , Zhang Jincang , Che Renchao , Wu Limin 
Published: April 2023

Abstract
With the development of the single-atom catalysts in electrocatalysis, the existence of metal nanoclusters in metal-N-C based materials have been proved. However, the effect of metal nanoclusters on electrocatalysis is hard to be confirmed. Herein, a novel framework of NCNTs with Fe nanoclusters and Fe-N-C sites (Fe3C-NCNTs 90min/CC) have been synthesized as the platform confirmed by Cs-corrected TEM and HADDF-STEM. Compared the samples immersed in HCl to remove Fe nanoclusters (HCl-Fe3C-NCNTs 90min/CC), the composite exhibits strong polarization and electron modulation effect onside the surface of NCNTs confirmed by holography. The electrocatalytic performance of Fe3C-NCNTs 90min/CC reduced significantly after the acid-treatment with a half-wave potential of 0.88 to 0.78V for ORR and an overpotential of 380mV to 510mV at 10mA cm− 2 for OER in alkaline solution. Furthermore, such a bifunctional catalyst endows the homemade ZAB with high power density and long-term stability, outperforming commercial Pt/C-RuO2 catalysts. The density functional theory (DFT) calculation indicates that the multiatom Fe-N-C sites significantly accelerate the desorption of OH* intermediates and thus promote the ORR process. This work paves a facile route to design the cluster-modulated interactions towards electrocatalysts and reveals the roles and effects on the metal nanoclusters for ORR/OER performance.
Improving assessment and escalation of threatened haemodialysis access: Results of a nursing-led program
Authors: Forcey Dana , Tran Dan , Connor Jenny , Ayudhya Piriya Kusuma Na , Ocampo Christian , Nelson Craig , Crikis Sandra 
Published: April 2023

Abstract
Background
Optimal vascular access is critical to successful haemodialysis. Acute thrombosis of haemodialysis access often leads to unplanned hospital admissions and interventions to restore patency.
Western Health is a large health service in Victoria, Australia. During the period February 2019 to January 2020, the rate of arteriovenous fistula (AVF) and graft (AVG) at Western Health satellite dialysis units was 0.33 episodes per 1000 patient-days, higher than the reported rate in the literature of 0.24 events per 1000 patient-days, and was associated with a cumulative total of 139 days of inpatient stay (2.2 per 1000 patient-days).
Methods
The above results prompted creation of an education and escalation pathway for threatened haemodialysis access, based upon clinical markers of vascular access stenosis or imminent thrombosis assess by nursing staff in satellite haemodialysis centres.
In the period February 2020 to January 2021, an education and escalation pathway was implemented. We then assessed numbers of referrals via the pathway and rates of AVF/AVG thrombosis in the following 12-month period (February 2021 to January 2022).
Results
Following introduction of the pathway, rates of AVF/AVG thrombosis declined to 0.15 per 1000 patient-days (p=0.02), associated with a decline in attributable cumulative inpatient stay to 55 days (0.69 per 1000 patient-days).
Conclusions
Our program demonstrates that the majority of thrombosed vascular access can be predicted and potentially averted with vigilant and well-practiced routine clinical assessment by trained nursing staff. Our nursing-led education and escalation program successfully identified vascular access at risk of imminent thrombosis, reduced rates of acute thrombosis and associated healthcare costs.
Despite these improvements, there are still disparities in outcomes for patients with thrombosed vascular access, with regards to length of stay and requirement for insertion of a temporary CVC for urgent dialysis whilst awaiting intervention, and these are areas for further investigation and improvement.
Recovery of idiopathic macular hole at different stages after surgery: A Systematic Review and Meta-analysis
Authors: Liao YanYing , Shen Yu , Li Xiaoxia , Wu Miaoqin 
Published: April 2023

Abstract
Background

A systematic review and meta-analysis was conducted to assess the visual function and microstructure recovery of idiopathic macular hole (IMH) at different stages after surgery and its relationship.

Methods

We systematically searched electronic database from PubMed, Embase and Cochrane Library before June 2022. The primary outcome parameter was the best corrected visual acuity (BCVA) at different time periods after surgery, while the secondary outcome parameter was the percentage or length of recovery of external limiting membrane (ELM) and ellipsoid zone (EZ) at different periods.

Results

This meta-analysis included 328 eyes from 10 studies. The pooled BCVA significantly improved at every stage (P < 0.05). At the same time, ELM and EZ defects repaired significantly in 1–3 months and 3–6 months after surgery (P < 0.05), which confirmed that 1–6 months were the key time for the rearrangement of the outer layer of the retina. Moreover, EZ layer continued to recover (P < 0.05) during six months after operation. Moreover, there was a significant positive correlation between ELM and EZ (P < 0.0001).

Conclusions

Recovery of visual function was significantly correlated with ELM layer and EZ layer. The repair of ELM is always prior to that of EZ, and the rearrangement of layers often occurs in 1–6 months. Patients’ vision continued to improved after operation.
Multi-elemental consumer-driven nutrient cycling when predators feed on different prey
Authors: Herzog Colton , Reeves Jacob , Ipek Yetkin , Jilling Andrea , Hawlena Dror , Wilder Shawn 
Published: April 2023

AbstractPredators play a fundamental role in cycling nutrients through ecosystems, by altering the amount and compositions of waste products and uneaten prey parts available to decomposers. Different prey can vary in their elemental content and the deposition of elements in predator waste can vary depending on which elements are preferentially retained versus eliminated as waste products. We tested how feeding on different prey (caterpillars, cockroaches, crickets, and flies) affected the concentrations of 23 elements in excreta deposited by wolf spider across two seasons (spring versus fall). Spider excreta had lower concentrations of carbon and higher concentrations of many other elements (Al, B, Ba, K, P, S, Si, Sr, and V)compared to prey remains, and whole prey carcasses. Additionally, elemental concentrations in unconsumed whole prey carcasses and prey remains varied between prey species, while spider excreta had the lowest variation among prey species. Finally, the concentrations of elements deposited differed between seasons, with wolf spiders excreting greater concentrations of Fe, Mg, Mn, Mo, S, & V in the fall. However, in the spring spiders excreted higher concentrations of Al, B, Ba, Ca, Cd, Cu, K, P, Na, Si, Sr, and Zn. These results highlight that prey identity and environmental variation can determine the role that predators play in regulating the cycling of many elements. A better understanding of these convoluted nutritional interactions is critical to disentangle specific consumer-driven effects on ecosystem function.
Integrative proteomic and phosphoproteomic analysis in the female goat hypothalamus to study the onset of puberty
Authors: Ye Jing , Yan Xu , Zhang Wei , Lu Juntai , Xu Shuangshuang , Li Xiaoqian , Qin Ping , Gong Xinbao , Liu Ya , Ling Yinghui , Li Yunsheng , Zhang Yunhai , Fang Fugui 
Published: April 2023

Abstract
Background: Puberty marks the end of childhood and achieve sexual maturation and fertility. The role of hypothalamic proteins in regulating puberty onset is unclear. We performed a comprehensive differential proteomics and phosphoproteomics analysis in prepubertal and pubertal goatsto determine the roles of hypothalamic proteins and phosphoproteins during the onset of puberty.
Results: We used peptide and posttranslational modifications peptide quantification and statistical analyses, and identified 67 differentially expressed proteins from 5,057 proteins and 576 differentially expressed phosphopeptides from 1574 phosphorylated proteins. Combined proteomic and phosphoproteomics, 759 correlated proteins were identified, of which 5 were differentially expressed only at the protein level, and 201 were only differentially expressed at the phosphoprotein level. Pathway enrichment analyses revealed that the majority of correlated proteins were associated with glycolysis/gluconeogenesis, Fc gamma R-mediated phagocytosis, focal adhesion, GABAergic synapse, and Rap1 signaling pathway. These pathways are related to cell proliferation, neurocyte migration, and promoting the release of gonadotropin-releasing hormone in the hypothalamus. CTNNB1 occupied important locations in the protein-protein interaction network and is involved in focal adhesion.
Conclusion: The results demonstrate that the proteins differentially expression only at the protein level or only differentially expressed at the phosphoprotein level and their related signalling pathways are crucial in regulating puberty in goats. These differentially expressed proteins and phosphorylated proteins may constitute the proteomic backgrounds between the two different stages.
Characteristics and orientation of elderly patients in the largest French psychiatric emergency centre : a prospective cohort study
Authors: PHAM-SCOTTEZ Alexandra , GALLARDA Thierry , CALVEZ Mathilde , SILVA Jérôme , David BARRUEL , MASSON DAURIAC-LE MASSON , LAHAYE Justine , PERQUIER Florence , SARAZIN Marie , GOUREVITCH Raphael 
Published: April 2023

Abstract
Background
Although there is an increasing number of adults older than 60 years old (>60) suffering from psychiatric disorders, there are only few studies about elderly patients in psychiatric emergencies, and no European data. The goal of our study is to describe the population of patients > 60 consulting in the most important French emergency psychiatric centre, and to identify predictive factors of psychiatric hospitalisation.
Methods
Our study was monocentric and prospective, including 300 consecutive patients > 60.
Results
Patients > 60 consulting in psychiatric emergencies were more often females and autonomous. More than 40% had a history of at least one psychiatric hospitalisation, and 44% had consulted a psychiatrist in the 6 preceding months. 75% were taking at least 1 psychotropic drug, and 50% at least 2. The most frequent reasons for consultation were depression, anxiety, sleep disorders and suicidal thoughts. Psychiatric disorders were mainly mood disorders, neurotic, stress-related and somatoform disorders, and schizophrenia, schizotypal and delusional disorders. Organic, including symptomatic, mental disorders were diagnosed in only 10% of the total sample. 39% of elderly patients were hospitalised in psychiatry. Factors predicting hospitalisation were a history of psychiatric hospitalisation, suicidal thoughts, and a diagnosis of mood disorder or schizophrenia / schizotypal / delusional disorder.
Conclusion
Only psychiatric factors intervene in the decision of psychiatric hospitalisation for elderly people consulting in psychiatric emergencies. Socio-demographic characteristics, level of autonomy at home and MMSE score have no influence on the hospitalisation decision. We need more data to better understand the current and future needs of this population.
Optimal emissivity Control of N Population system Based on Individual Size-Distribution
Authors: Ba Zhenggang , Wang Ye 
Published: April 2023

Abstract
This paper generalizes a class of controllability problems based on the scale structure population system model. Based on the comparison principle of linear systems, the solution of the nonlinear system model is obtained by referring to the fixed point theorem. The non-negative, boundedness, existence, and uniqueness of the solution of the system model are established. The optimality condition is described in detail by means of a normal cone and conjugate system under the condition of proving the continuous dependence of the state environment on the solution to control variables.
In vitro storage of functional sperm at room temperature in zebrafish and medaka
Authors: Takemoto Kazumasa , Nishimura Toshiya , Kawasaki Toshihiro , Imai Yukiko , Tanaka Minoru , Sakai Noriyoshi 
Published: April 2023

Abstract
The longevity of sperm in teleost is short when isolated even in saline-balanced solution at a physiological temperature. In contrast, some internal fertilizers exhibit the long-term storage of sperm in the female reproductive tract. This evidence raises the question of whether sperm even from the external fertilizer possesses the ability to survive for a long time under appropriate conditions. Here, we show that the sperm of the external fertilizer, zebrafish, can survive and maintain fertility in L-15-based storage medium supplemented with bovine serum albumin, foetal bovine serum, glucose and lactic acid for 28 days at room temperature. The fertilized embryos developed to normal fertile adults. This storage medium was effective in another external fertilizer medaka sperm stored for 7 days at room temperature. These results reveal that sperm from external fertilizer teleost has the ability to survive in vitro for a long time. This sperm storage method allows to ship sperm in important lines by low-cost methods and to investigatekey factors for motility and fertile ability in teleost sperm.
Viral and immunologic evaluation of smokers with severe COVID-19
Authors: Vecchio Joseph , Regan James , Jiang Yuting , Li Roy , Romain Hannah , Yousuf Fizah , Adel Thomas , Hall Kevin , DaCosta Jeffrey M. , Yu Xu , Li Jonathan Z. , Fofana Ismael Ben 
Published: April 2023

Abstract
Smoking negatively affects B cell function and immunoglobulin levels, but it is unclear if this immune dysfunction contributes to the risk of severe COVID-19 in smokers. We evaluated binding IgM, IgA and IgG antibodies to spike and receptor binding domain antigens, and used a pseudovirus assay quantify neutralization titers in a set of 27 patients with severe COVID-19. We found no significant differences between binding and neutralization antibody responses for people with a smoking history and people who never smoked. High plasma viral load, but not antibody titers, was linked to an increased risk of death. Humoral immune dysfunction was not a major driver of severe COVID-19 in smokers.
Gut microbiota dysbiosis and increased plasma trimethylamine N-oxide in patients with chronic kidney disease
Authors: Zou Wenli , Liu Yueming , Zhang Wei , Shen Wei , Lin Bo 
Published: April 2023

Abstract
Background
The gut microbiota has been identified as a source of pathogenic mediators in chronic kidney disease (CKD). A gut microbiota-dependent metabolite, trimethylamine N-oxide (TMAO), has been reported to be closely related to CKD complications. This study aimed to investigate the changes in intestinal microbiota and circulating levels of TMAO in Chinese patients with CKD.
Methods
The study comprised 50 paticipants including 30 patients with CKD and a control group of 20 healthy controls. Plasma TMAO levels were detected by high-performance liquid chromatography-tandem mass spectrometry, and gut microbiota was analysed using High-throughput sequencing.
Results
Compared to the healthy control group, the CKD patients had relatively lower albumin and hemoglobin levels and showed obviously impaired renal function and abnormal urine test results. Additionally, CKD patients showed increased plasma TMAO levels, especially those with a low glomerular filtration rate (GFR). Among the biochemical indices of the CKD patients, impaired renal function was the main contributor of the increased TMAO levels. High-throughput sequencing revealed obvious gut dysbiosis in CKD patients with biased community constitutions. Based on the Pearson correlation analysis, many bacteria positively or negatively correlated with TMAO production at the phylum and genus levels.
Conclusions
Our study demonstrated that gut microbiota dysbiosis and decreased GFR were the main causes of plasma TMAO level. Elevation, and inhibition of intestinal metabolite TMAO production may be the key to preventing CKD progression.