bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of surface retaining elements on rock stability: laboratory investigation with sand powder 3D printing
Authors: Feng Hao , Jiang Lishuai , Wang Qingwei , Tang Peng , Sainoki Atsushi , Mitri Hani S. 
Published: September 2023

AbstractThis study aims to investigate the beneficial effects of surface retaining elements (SREs) on the mechanical behaviors of bolted rock and roadway stability. 3D printing (3DP) technology is utilized to create rock analogue prismatic specimens for conducting this investigation. Uniaxial compression tests with acoustic emission (AE) and digital image correlation techniques have been conducted on 3DP specimens bolted with different SREs. The results demonstrate that the strength and modulus of elasticity of the bolted specimens show a positive correlation with the area of the SRE; the AE characteristics of the bolted specimens are higher than those of the unbolted specimen, but they decrease with an increase in SRE area, thus further improving the integrity of the bolted specimens. The reinforcement effect of SREs on the surrounding rock of roadways is further analyzed using numerical modelling and field test. The results provide a better understanding of the role of SREs in rock bolting and the optimization of rock bolting design. Furthermore, they verify the feasibility of 3DP for rock analogues in rock mechanics tests.
Bento Almeida d’Eça: Hydraulic Agriculture under the umbrella of Engineers in Nineteenth Century Portugal
Authors: Rodrigues Ana Duarte , Pireddu Pier Luigi , Monteiro Patricia Trindade 
Published: September 2023

AbstractIn mid-nineteenth century Portugal, the practice of irrigation was deemed to be completely backwards in comparison with the prevailing European standards. Distant were the times of Al-Andalus, when a so-called green revolution occurred on the Iberian Peninsula. Within this context, Agricultural Hydraulics gained momentum as a scientific field. Although water governance had a long run, the ‘politicisation’ of water issues clearly intensified in the Regeneration political regime. From 1851 onwards, the stability required for national material progress was ensured. The country had been struggling to build roads, railways, telegraphs, ports and, therefore, the Ministry of Public Works was established in 1852 to undertake these architectural and engineering projects. This paper argues that not only due to rivers’ manipulation for agriculture, but also to the rising status of engineers, Agricultural Hydraulics was under the Ministry of Public Works and, consequently, on the sphere of engineers rather than agronomists. Focusing on the making of a military engineer as an expert on Agricultural Hydraulics by sending him abroad and fostering his literary education, this paper reveals how this knowledge was appropriated and transformed into new projects for the Tagus River. Moreover, contrary to recent review that Hydraulic Services were launched in Portugal by 1884, based on the “Plan for Organization of Hydrographic Services on the mainland of Portugal”, this paper highlights the crucial role played by the Portuguese engineer Bento Fortunato Almeida d’Eça through his work as Superintendent of the Tagus River and its Tributaries, twenty years earlier.
Producing of alkali-activated artificial aggregates by pelletization of fly ash, slag, and seashell powder
Authors: Bekkeri Gopal Bharamappa , Shetty Kiran K. , Nayak Gopinatha 
Published: September 2023

AbstractIn the construction sector, the material supply chain of aggregates is frequently disturbed due to seasonal unavailability, quarrying issues, and environmental norms. The production of artificial aggregates has gained prominence to conserve natural resources and promote green construction practices. The current study encompasses the production of alkali-activated artificial aggregates through cold-bonding pelletization technique using three different raw materials, including fly ash, ground granulated blast furnace slag, and seashell powder in binary and ternary blending combinations. The cold bonding was achieved by alkali activation of binders with the aid of a sodium-based alkaline solution, which acts as an activator and hydrating liquid. The fresh artificial aggregates were subjected to surface treatment using the same alkaline solution to enhance their characteristics. The mechanical properties of artificial aggregates confirmed their potential as a substitute for conventional aggregates by exhibiting crushing and impact values of 18.19–27.53% and 12.06–18.85%, respectively. The microstructural and mineralogical characteristics depicted dense microstructure and compact matrix. The study concludes that artificial aggregates can effectively replace natural coarse aggregate in making structural concrete with many economic, environmental, and technical advantages.
The World Psychiatric Association Telepsychiatry Global Guidelines
Authors: Mucic Davor , Shore Jay , Hilty Donald M. 
Published: September 2023

AbstractPsychiatry is the branch of medicine that deals with the causation, prevention, diagnosis, and treatment of mental and behavioral disorders. Telepsychiatry, in the form of live interactive videoconferencing, has emerged as a promising approach to improve access to mental health care, particularly in underserved populations across the world. However, the use of telepsychiatry also raises unique clinical, ethical, legal, and technological challenges. Pre-pandemic, the vast majority of mental health professionals had little to no experience with telepsychiatry, so they were forced to quickly adapt to the use of telepsychiatry to continue provide ongoing care to patients or new services. To address these challenges, the World Psychiatric Association (WPA) developed Telepsychiatry Global Guidelines in 2020 via outreach to and input from as many countries as possible, with intent to support all countries with intent to specifically assist low- and middle-income countries in adopting and establishing telepsychiatry services amid the COVID-19 outbreak. The guidelines make suggestions for clinical practice, technological challenges, education and training, research, and specific populations and settings, with an emphasis on international and cross-cultural dimensions. The WPA guidelines specifically emphasize the importance of providing cultural fit to patient-centered care, ensuring confidentiality and security of patient information, and ongoing evaluation and quality improvement. The guidelines offer an appendix with a comprehensive collection of tools, templates, and resources. The guidelines highlight the importance of collaboration between policymakers, clinicians, and patients in the development and implementation of telepsychiatry programs.
Circulation in Seventeenth-Century Lisbon (Portugal): Traffic Signs and Traffic Rules
Authors: Castro Inês , Santos Joel , Casimiro Tânia Manuel 
Published: September 2023

AbstractBy the 17th century, Lisbon was a large and complex city—the capital of a large empire in which thousands of people and goods originating from different places around the world circulated. Yet the city was still organized according to its medieval footprint, one consequence of which was numerous documented traffic problems. In 1686, King Pedro II decreed that places in Lisbon where the problems were most recurrent should be marked with signs establishing circulation rules. Consequently, 24 such signs were put up in different parts of the city, three of which still survive today, even after the destruction of the 1755 earthquake. Based on archaeological, historical, cartographic, and geographic information, this article aims to discuss how these signs are a reflection of medieval Lisbon’s circulatory patterns and how the narrow streets were not able to adequately support the circulation of large vehicles introduced in the 17th century. The combination of this information not only allows the recreation of Lisbon’s circulation patterns, but also parts of the city’s social and cultural landscape as well.
A Bionic Starfish Adsorption Crawling Soft Robot
Authors: Huang Xiangang , Zhang Chenghao , Feng Wenqi , Zhang Xiangye , Zhang Deyuan , Liu Yanqiang 
Published: September 2023

AbstractA variety of soft wall-climbing robots have been developed that can move in certain patterns. Most of these soft robots can only move on conventional surfaces and lack adaptability to complex surfaces. Improving the adaptability of soft robots on complex surfaces is still a challenging problem. To this end, we study the layered structure of the starfish tube foot and the valve flap structure in the water vascular system, and use an ultrasonic stress detector to study the stiffness distribution of the arm structure. Inspired by the motion of the starfish, we present a bionic soft wall-climbing robot, which is driven by two groups of pneumatic feet and achieves body bending through active adaptation layers. We design the structure of the foot to flex to provide driving force, and there are suction cups at the end of the foot to provide suction. The soft foot has a simple structure design, adapts to a variety of surfaces, and does not damage the surface of the substrate. Variable stiffness layers achieve stiffness changes by the principle of line blocking. The Central Pattern Generator theory is introduced to coordinately control the multiple feet of the robot. After experiments, we verify the adaptability of the soft robot to curved surfaces. The research may provide a reference for the design and development of crawling soft robots on complex surfaces.
Friedensbildung otherwise?
Authors: Krohn Juliana , Pauls Christina 
Published: September 2023

ZusammenfassungAuf Basis dekolonialer Theorien wird in diesem Beitrag ausgelotet, ob und wie Friedensbildung eine dekoloniale Ausrichtung erfahren kann. Hierzu werden die Kontexte und Implikationen des decolonial turn in der Friedens- und Konfliktforschung und der Friedensbildung nachgezeichnet. Im Fokus des Beitrags steht die Konturierung einer dekolonial informierten Friedensbildung als Wegbereiterin für eine Friedensbildung otherwise. Eine dekolonial informierte Friedensbildung nimmt die Möglichkeiten und Herausforderungen von Friedensbildung in den Blick und beruht auf der Kritik des dominanten modern-liberalen Friedensbegriffes, auf der Erweiterung des Gewaltbegriffs um eine onto-epistemische Ebene, sowie auf einer Pluriversalisierung von Friedensverständnissen vor dem Hintergrund der Auseinandersetzung mit (De)Kolonialität. Die Analyse und Hinterfragung eines von kolonialen Herrschafts‑, Gewalt- und Machtverhältnissen geprägten Status Quo ist dabei grundlegend, um diese Verhältnisse in der Friedensbildung einer Bearbeitung zugänglich zu machen.
Whole-Exome Sequencing Analysis of Idiopathic Hypogonadotropic Hypogonadism: Comparison of Varicocele and Nonobstructive Azoospermia
Authors: Ma Ziyang , Dai Yi , Jin Lei , Luo Yi , Guo Chen , Qu Rui , He Shengyin , Liu Yugao , Xia Yu , Liu Huan , Kong Lingnan , Xu Miaomiao , Zhang Lanlan , Zhao Yue , Suliya Yushanjiang , Yuan Dongzhi , Yang Luo 
Published: September 2023

AbstractAs a rare disease leading to male infertility, idiopathic hypogonadotropic hypogonadism (IHH) has strong heterogeneity of clinical phenotype and gene mutation. At present, there is no effective diagnosis and treatment method for this disease. This study is to explore the possible new pathogenic gene of idiopathic hypogonadotrophic hypogonadism and the pathological mechanism affecting its occurrence. We performed a whole-exome sequencing on 9 patients with normosmic idiopathic hypogonadotropic hypogonadism (nIHH), 19 varicocele patients with asthenospermia, oligospermia, or azoospermia, 5 patients with simple nonobstructive azoospermia, and 13 normal healthy adult males and carried out comparative analysis, channel analysis, etc. After preliminary sequencing screening, 309–431 genes harbouring variants, including SNPs and indels, were predicted to be harmful per single patient in each group. In genetic variations of nIHH patients’ analysis, variants were detected in 10 loci and nine genes in nine patients. And in co-analysis of the three patient groups, nine nIHH patients, 19 VC patients, and five SN patients shared 116 variants, with 28 variant-harbouring genes detected in five or more patients. We found that the NEFH, CCDC177, and PCLO genes and the Gene Ontology pathways GO:0051301: cell division and GO:0090066: regulation of anatomical structure size may be key factors in the pathogenic mechanism of IHH. Our results suggest that the pathogenic mechanism of IHH is not limited to the central nervous system effects of GnRH but may involve other heterogeneous pathogenic genetic variants that affect peripheral organs.
Pten knockout affects drug resistance differently in melanoma and kidney cancer
Authors: Brodaczewska Klaudia , Majewska Aleksandra , Filipiak-Duliban Aleksandra , Kieda Claudine 
Published: September 2023

Abstract
Background
PTEN is a tumor suppressor that is often mutated and nonfunctional in many types of cancer. The high heterogeneity of PTEN function between tumor types makes new Pten knockout models necessary to assess its impact on cancer progression and/or treatment outcomes.

Methods
We aimed to show the effect of CRISPR/Cas9-mediated Pten knockout on murine melanoma (B16 F10) and kidney cancer (Renca) cells. We evaluated the effect of PTEN deregulation on tumor progression in vivo and in vitro, as well as on the effectiveness of drug treatment in vitro. In addition, we studied the molecular changes induced by Pten knockout.

Results
In both models, Pten mutation did not cause significant changes in cell proliferation in vitro or in vivo. Cells with Pten knockout differed in sensitivity to cisplatin treatment: in B16 F10 cells, the lack of PTEN induced sensitivity and, in Renca cells, resistance to drug treatment. Accumulation of pAKT was observed in both cell lines, but only Renca cells showed upregulation of the p53 level after Pten knockout. PTEN deregulation also varied in the way that it altered PAI-1 secretion in the tested models, showing a decrease in PAI-1 in B16 F10 Pten/KO and an increase in Renca Pten/KO cells. In kidney cancer cells, Pten knockout caused changes in epithelial to mesenchymal transition marker expression, with downregulation of E-cadherin and upregulation of Snail, Mmp9, and Acta2 (α-SMA).

Conclusions
The results confirmed heterogenous cell responses to PTEN loss, which may lead to a better understanding of the role of PTEN in particular types of tumors and points to PTEN as a therapeutic target for personalized medicine.
The Heterogeneity of Social Network and Institutional Covariance in the American Southeast
Authors: Holland-Lulewicz Jacob 
Published: September 2023

AbstractSocial, political, and economic institutions covary with one another in heterogenous ways across space and time. Social Network Analysis (SNA) offers a set of analytical tools and conceptual frameworks that have allowed for formal comparisons of interactions, affiliations, and relationships in reconstructing historical trajectories of institutional change. Although archaeologists have made full use of a range of metrics that describe the structural variation of social networks, formal approaches to analyzing the covariance of networks, and the institutions that structured networks in the past, remain undertheorized. In most cases, descriptive metrics are compared between networks built from different datasets or networks separated in time. Using quadratic assignment procedure (QAP) correlations to compare matrices of archaeological data, I draw on a ceramic dataset of approximately 350,000 sherds from the Southern Appalachian region to investigate how decisions related to manufacture choice and to stylistic design covaried with one another between roughly AD 800 and 1650. I explore how material attributes may or may not vary independently of one another and what that means for our analyses of the institutions they reflect. The results contribute to broader comparative analyses of institutional change and perennial discussions of social evolution.
Validation of the STERIS Amsco 630LS steam sterilizer autoclave for inactivation of category a medical waste from patients with high-consequence infectious diseases
Authors: Tarabay Jessica A. , Morgan Jill S. , Kraft Colleen S. , Sexton Mary Elizabeth 
Published: September 2023

AbstractHospitals caring for patients with high-consequence pathogens may need to safely manage large volumes of category A waste. Using biological indicators to assess for successful sterilization, autoclave cycle parameters that would inactivate 4 categories of waste were identified and validated utilizing a STERIS Amsco 630LS Steam Sterilizer.
Elongate Ediacaran fronds from the Flinders Ranges, South Australia
Authors: Grimes Kelsey F. , Narbonne Guy M. , Gehling James G. , Trusler Peter W. , Dececchi T. Alexander 
Published: September 2023

AbstractDecimeter-scale, elongate, fossil fronds from the Ediacara Range in South Australia were formally described as Rangea longa Glaessner and Wade, 1966, but the disparate nature of documented specimens has hindered their inclusion in global syntheses and has resulted in these fossils being assigned to at least five different genera in two different clades since their discovery. Detailed study of the type material from the Ediacara Range and the few specimens subsequently collected elsewhere in the Flinders Ranges reaffirms that these specimens represent a single species, with the apparent morphological variation between specimens entirely taphonomic and reflecting the obverse and reverse surfaces of these fronds coupled with the orientation of the frond axis and petaloids at different angles relative to the sea bottom on which they were preserved. The preserved architecture of these fronds constitutes three orders of branching microstructure that are strictly orthogonal to immediately higher and lower orders. This implies affinities with the arboreomorphs, but representing a new frond genus herein named Akrophyllas. Akrophyllas n. gen. differs from all other Ediacaran fronds in exhibiting a stalk that is visible only on one side of the frond and is internal to the other side where the first-order branches instead meet at a zigzag axial trace. Akrophyllas n. gen. was attached to a bulbous holdfast on the sea bottom, and evidence for current scours that formed in the lee of the fronds and for a strong current alignment of felled fronds with depositional overlap of adjacent fronds imply an upright, epibenthic lifestyle for Akrophyllas longa new combination.UUID: http://zoobank.org/86e26477-7b1e-45da-870c-1b5d28fc510c
The interpretation of policies in administrative law: the significance of audience
Authors: Mills Alistair 
Published: September 2023

AbstractThe interpretation of administrative policies is of great importance in contemporary public law. The correct approach to policy interpretation has, however, been subject to insufficient academic scrutiny. The effect of policies is to provide guidance: not only to decision-makers, but also to stakeholders in the decision. Obvious stakeholders include the applicant or the individual who is the subject of the administrative decision, but the scope of potential legitimate stakeholders may go far beyond this. In matters of general interest, the broader public may be guided by policy (for instance, whether to object to a proposal during a consultation exercise, or on what basis to object). When considering how policy should be interpreted, the court should have regard to the extent of the appropriate audience of the policy, specifically considering how the least expert reader of the policy would interpret it. This ‘least expert reader principle’ will assist in answering difficult questions, such as whether the court should have regard to the underlying evidence base when interpreting a policy. The courts should rely upon, and express their reasoning by reference to, the least expert reader principle, in order to increase the transparency of judgments in the field of policy interpretation.
Constrained by Localized Attention Focus: The Negative Effect of Firm-Specific Knowledge on Exploratory Firm Innovation
Authors: Sullivan Bilian Ni , Mao Kaixian , Wang Heli 
Published: September 2023

AbstractIntegrating the resource-based view (RBV) and attention-based view (ABV), this study explores the impact of firm-specific knowledge (FSK) on a firm's exploratory innovation and the role of government support in this process. We argue that firms with a high degree of specificity in their knowledge assets tend to have a more localized attention focus, leading to those firms with less exposure to distant and diverse information and knowledge. Consequently, such firms are likely to have reduced exploratory innovative outputs. However, government resource support could expand a firm's attention focus beyond local searches, mitigating its negative effects. Based on a unique combined two-wave survey and archival data from over 500 firms in China, we find that the level of FSK is negatively related to a firm's exploratory innovation output. We provide evidence that localized attention focus partially mediates the negative effect of FSK on firms’ exploratory innovation. We further reveal that state ownership and state financial support for firm innovation weaken the negative main effect. This study makes important contributions to the literatures on the RBV, FSK, and firm innovation.
TILINGS OF THE SPHERE BY CONGRUENT QUADRILATERALS II: EDGE COMBINATION WITH RATIONAL ANGLES
Authors: LIAO YIXI , WANG ERXIAO 
Published: September 2023

AbstractEdge-to-edge tilings of the sphere by congruent quadrilaterals are completely classified in a series of three papers. This second one applies the powerful tool of trigonometric Diophantine equations to classify the case of
$a^3b$
-quadrilaterals with all angles being rational degrees. There are
$12$
sporadic and
$3$
infinite sequences of quadrilaterals admitting the two-layer earth map tilings together with their modifications, and
$3$
sporadic quadrilaterals admitting
$4$
exceptional tilings. Among them only three quadrilaterals are convex. New interesting non-edge-to-edge triangular tilings are obtained as a byproduct.
MULTIPLIERS AND CHARACTERIZATION OF THE DUAL OF NEVANLINNA-TYPE SPACES
Authors: MASTYŁO MIECZYSŁAW , STANIÓW BARTOSZ 
Published: September 2023

AbstractThe Nevanlinna-type spaces
$N_\varphi $
of analytic functions on the disk in the complex plane generated by strongly convex functions
$\varphi $
in the sense of Rudin are studied. We show for some special class of strongly convex functions asymptotic bounds on the growth of the Taylor coefficients of a function in
$N_\varphi $
and use these to characterize the coefficient multipliers from
$N_\varphi $
into the Hardy spaces
$H^p$
with
$0<p\leqslant \infty $
. As a by-product, we prove a representation of continuous linear functionals on
$N_\varphi $
.
Hypothesis Tests under Separation
Authors: Rainey Carlisle 
Published: September 2023

AbstractSeparation commonly occurs in political science, usually when a binary explanatory variable perfectly predicts a binary outcome. In these situations, methodologists often recommend penalized maximum likelihood or Bayesian estimation. But researchers might struggle to identify an appropriate penalty or prior distribution. Fortunately, I show that researchers can easily test hypotheses about the model coefficients with standard frequentist tools. While the popular Wald test produces misleading (even nonsensical) p-values under separation, I show that likelihood ratio tests and score tests behave in the usual manner. Therefore, researchers can produce meaningful p-values with standard frequentist tools under separation without the use of penalties or prior information.