bluuebunny/crossref_metadata_2025_split huggingface dataset:
Galacto-oligosaccharides fed during gestation increase Rotavirus A specific antibodies in sow colostrum, modulate the microbiome, and reduce infectivity in neonatal piglets in a commercial farm setting
Authors: Lee Adam , Liang Lu , Connerton Phillippa L. , Connerton Ian F. , Mellits Kenneth H. 
Published: February 2023

IntroductionRotavirus A is a major cause of acute dehydrating diarrhea in neonatal pigs resulting in significant mortality, morbidity, reduced performance and economic loss. Commercially available prebiotic galacto-oligosaccharides are similar to those of mammalian milk and stimulate the development of the microbiota and immune system in neonates. Little is known about the effects of supplementing sows' diets with galacto-oligosaccharides during gestation. This study aimed to determine if dietary galacto-oligosaccharide supplementation during gestation could improve immunity, reduce rotavirus infection and modulate the microbiota in sows and neonates in a commercial farm setting with confirmed natural endemic rotavirus challenge.MethodsIn a randomized controlled trial, control sows received lactation diet with no galacto-oligosaccharide supplementation and test sows received lactation diet with 30 g/day galacto-oligosaccharide top-dressed into feed daily, seven days before farrowing. Colostrum was collected from sows 24 hours post-partum and tested for rotavirus specific antibodies. Fecal samples were collected from sows and piglets three days post-partum, tested for rotavirus A by qPCR and the microbiome composition assessed by 16s rRNA gene sequencing.ResultsSupplementation with galacto-oligosaccharides during gestation significantly increased rotavirus-specific IgG and IgA in sow colostrum and reduced the number of rotavirus positive piglet fecal samples. Abundance of potential pathogens Treponema and Clostridiales were higher in fecal samples from non-galacto-oligosaccharide fed sows, their piglets and rotavirus positive samples.DiscussionThis study demonstrates that galacto-oligosaccharide supplementation during gestation significantly increases rotavirus specific IgG and IgA in sow colostrum thereby reducing neonatal rotavirus infection and suppresses potential pathogenic bacteria in nursing sows and neonatal piglets.
Cohort size required for prognostic genes analysis of stage II/III esophageal squamous cell carcinoma
Authors: Kong Linghong , Yang Ming , Wan Zhiyi , Wang Lining 
Published: February 2023

Background: Few overlaps between prognostic biomarkers are observed among different independently performed genomic studies of esophageal squamous cell carcinoma (ESCC). One of the reasons for this is the insufficient cohort size. How many cases are needed to prognostic genes analysis in ESCC?Methods: Here, based on 387 stage II/III ESCC cases analyzed by whole-genome sequencing from one single center, effects of cohort size on prognostic genes analysis were investigated. Prognostic genes analysis was performed in 100 replicates at each cohort size level using a random resampling method.Results: The number of prognostic genes followed a power-law increase with cohort size in ESCC patients with stage II and stage III, with exponents of 2.27 and 2.25, respectively. Power-law curves with increasing events number were also observed in stage II and III ESCC, respectively, and they almost overlapped. The probability of obtaining statistically significant prognostic genes shows a logistic cumulative distribution function with respect to cohort size. To achieve a 100% probability of obtaining statistically significant prognostic genes, the minimum cohort sizes required in stage II and III ESCC were approximately 95 and 60, respectively, corresponding to a number of outcome events of 33 and 36, respectively.Conclusion: In summary, the number of prognostic genes follows a power-law growth with the cohort size or events number in ESCC. The minimum events number required to achieve a 100% probability of obtaining a statistically significant prognostic gene is approximately 35.
Dynamic Characteristics of Periphytic Algae Communities on Different Substrates and the Host Response in Subtropical-Urban-Landscape Lakes
Authors: Peng Xue , Huang Suzhen , Yi Kelang , Zhang Lu , Ge Fangjie , Lin Qingwei , Zhang Yi , Wu Zhenbin , Liu Biyun 
Published: February 2023

Outbreaks of periphytic algae, including filamentous algae, have been observed after submerged macrophyte restoration and are common in early stages. Dynamic changes in the periphytic algae community on Vallisneria natans and artificial V. natans were investigated in situ, and their characteristics were compared on the two substrates. The results showed that more periphytic algae species occurred on V. natans (77 taxa) than on artificial V. natans (66 taxa) (F = 2.089, p = 0.047). The cell density and chlorophyll a (Chl. a) content of periphytic algae were 3.42–202.62-fold and 2.07–15.50-fold higher on the artificial substrate than on V. natans, respectively. Except for Lyngbya perelagans (i.e., the only common dominant periphytic algae species on the two substrates), the dominant species on V. natans were Cocconeis placentula and Ulothrix tenerrima, while those on the artificial substrate were Stigeoclonium aestrivale, Oscillatoria tenuis and Achnanthes minutissima. The cell density of periphytic algae was significantly affected by the total phosphorus (TP) and NO3−-N and electric conductivity on V. natans, and by TP and NH4+-N on artificial V. natans. The malondialdehyde content of V. natans was significantly correlated with the periphytic algae biomass. V. natans was more affected by periphytic algae during its slow-growing period, and the contribution order of stress to V. natans was diatoms > cyanobacteria > green algae. Our findings might contribute to the understanding the effect of substrate specificity on periphytic algae communities, and have important implications for the restoration of submerged plants in eutrophic lakes.
Феномен довіри в умовах цифровізації охорони здоров’я
Authors: Kurnosenko Larysa 
Published: February 2023

В статті піддано аналізу фактори впливу на формування довіри в системі охорони здоров’я. З’ясовано, що феномен довіри в науковому дискурсі розглядається на системному, інституційному та міжособистісному рівні і в переважній більшості наукових досліджень співвідноситься зі створеним позитивним іміджем суб’єкту в інформаційному просторі. Наголошено, що розуміння довіри в системі охорони здоров’я здебільшого формують одноманітні підходи соціологічного спрямування, що не дає змоги застосовувати їх для обґрунтування державно-управлінських рішень і формування державної політики в охороні здоров’я. Визначено, що на системному рівні органи публічного управління галуззю за допомогою використання інформації цифрових сервісів отримують можливість формувати фінансову, кадрову, інформаційну політику в охороні здоров’я, управляти ресурсами галузі в умовах виникнення системних криз, забезпечувати контроль над цільовим використанням бюджетних коштів. Визначено, що в умовах змін, важливе значення для формування довіри в охороні здоров’я має широке використання цифрових технологій та сервісів. Досліджено основні напрями впливу цифрових технологій на формування довіри в охороні здоров’я на системному, інституційному та міжособистісному рівні. Зроблено висновок, що цифрове інформаційне середовище, як комунікативний простір, має значний потенціал і може виступати не лише генератором довіри, а й засобом управління довірою, формуючи нові моделі комунікації між органами влади, громадськими організаціями, засобами масової інформації,закладами охорони здоров’я та населенням.
Нормативно-правове регулювання та інституційне забезпечення взаємодії органів державної влади та інститутів громадянського суспільства
Authors: Honcharuk Vasyl 
Published: February 2023

В статті автор розкриває важливу умову успіху публічного управління – це активна участь громадянського суспільства в усіх аспектах суспільно-політичного життя держави, що позитивно впливає на успішний розвиток суспільної демократії, зниження рівня таких соціально негативних явищ, як корупція, бідність, нетерпимість, екстремізм.
На думку автора статті, активна співпраця громадськості та влади допомагає побудувати суспільство, де люди довірятимуть одне одному і здатні спільними зусиллями вирішувати соціальні проблеми.
Метою статті є аналіз стану нормативно-правового регулювання та інституційного забезпечення взаємодії органів державної влади та інститутів громадянського суспільства на сучасному етапі розвитку суспільства та суспільно-владних відносин. Адже питання взаємодії органів державної влади та інститутів громадянського суспільства є одним з ключових питань суспільства упродовж всього його періоду існування. Від такої взаємодії залежить легітимність державної влади, її зміст та стабільність. Розвиток Української держави характеризується модернізацією всіх соціальних інститутів, що включені в процес демократичних перетворень. Однак ці зміни здійснюються нелегко та навіть пекельно, оскільки разом із пандемією супроводжуються боротьбою із зовнішнім ворогом – Російською Федерацією, яка здійснила 24 лютого 2022 р. підступний напад на Україну, розв’язала повномасштабну війну на території нашої держави, окупувавши й анексувавши у 2014 році Крим та частини Донецької й Луганської областей. Разом із тим спротив, що демонструє українське суспільство агресору, солідаризували навколо себе всі демократичні країни світу, і цей факт підкреслює незмінність курсу України на демократію, членство в ЄС та НАТО, яке громадянське суспільство активно підтримує. Тож зазначеним модернізаційним процесам розвитку України сприяють глобалізаційний рух, розвиток єдиного інформаційного простору, інноваційна, громадська активність суспільства.
The Linguistic Problem and The Thinking Skill in The Arabic Debate at the ICIS Club at UIN Kiai Haji Achmad Siqqiq in Jember
Authors: Hasanah Wihdatul , Maturedy Faris , Zaghloul Taha Ramadan 
Published: February 2023

The debate exercise was conducted for the new members of the ICIS Club at Kiai Hagi Ahmad Siddiq State Islamic University. They had problems with their workout. Therefore, the research aims to describe these problems, but this is limited to the linguistic problem and the problem of thinking efficiency. In this research, the qualitative research method was used. The data was collected through personal interview and observation. The data was therefore analyzed in a descriptive manner. The results of the research are that the new debaters face two problems throughout an Arabic debate exercise. They are the linguistic problem and the problem of thinking efficiency. The linguistic problem is that they are not used to using contemporary methods and vocabulary in the terminology of debate. The problem with thinking efficiency is that they do not use the three-Ds method to make the case for non-habituation. They are affirmation, reasoning and demonstration
Keywords: Speaaking Skill, Debate, HOTS
Computational Processes for General Intelligence The SEOM Model
Authors: Balakrishnan Prabhakar 
Published: February 2023

<p>The ‘brain-mind-intelligence’ structure may be considered analogous to a ‘computer-operating system (OS)-application’ construct. Software development would be far more difficult without the benefit of abstractions like file and memory handles, and graphical user interfaces, implemented in operating systems. The easy access to application-level semantics, provided by the infrastructure of the OS, simplifies application development. Abstractions can play a similar role in producing intelligent systems. The power of abstractions may be determined by their ability to unify the treatment of several types of higher concepts. Unifying various concepts in the domain of intelligence, such as problems, solutions, objects, and emotions, through abstractions will be of immense value. This paper shows how ‘higher-level perceptions’ could be used to serve this objective and construct an OS-like infrastructure. With the infrastructure in place, ordinary software objects developed and deployed using standard methods, become accessible using the semantics provided by the infrastructure. Now, after brief training exercises, the objects would be available for intelligent use. The focus, therefore, is on the design of the infrastructure that could play a mind-like role in humans.</p>
<p>The design uses a new, non-symbolic, non-connectionist, transmutable method of representation that tackles the so-called ‘frame’ and ‘grounding’ problems of artificial intelligence. The infrastructure enables the conversion of sensory inputs to transmutable representations amenable to semantic modifications, to flexibly determine actions to perform on software objects developed externally. Furthermore, the infrastructure serves to ground and functionally manage the transmutable, connectionist, and symbolic systems. Thus, the new model plays a critical role in building intelligent systems that overcome major problems in learning and action selection, including brittleness associated with the limited semantics of purely symbolic and connectionist designs. </p>
<p>The new model is then evaluated in terms of features, against criteria set forth independently by Newell, Sun, Vernon, and others. In addition, a new measure of intelligence introduced in this paper is used to quantitatively compare the proposed model with some others developed over the years. </p>
Trans Perspective in Software Engineering
Authors: Rocha Carla , Joranhezon marina , Malta Fleury Fabiola 
Published: February 2023

<p>The software industry employs few women and underrepresented minorities. Several initiatives from organizations, practitioners, and OSS communities address equity, diversity, and inclusion in software development. However, most of these initiatives deal in a generalist and simplistic way, often confusing diversity with gender diversity, reinforcing an industry with a homogeneous workforce, which has little room for the inclusion of sub represented communities. One of these communities is the transgender, who suffers from several intersections of oppression concerning gender, race, class, age, and disabilities, thus having voices erased in the industry.</p>
<p>Our research aims to identify the concepts of diversity in Software Engineering (SE) from a transgender perspective. We conduct a Systematic Grey Literature Review (GLR) to map the concepts around diversity in SE, focused on trans perspective. We detail our GLR, and inspired in Grounded Theory (GT) we have a coding protocol to build a concept map.</p>
<p>As a result, we obtained a concept map format, which illustrate some of the complexity of diversity issues in SE focused on trans people and how organizations and developers can contribute to trans inclusion in the software industry. </p>
<p>The paper starts a discussion regarding the perspective of trans people in the area. Research in diversity should observe the oppressions that exist and how they interact without simplifying and isolating issues such as treating gender in a binary way and not interconnected with other issues such as race. SE industry is strategic to the trans community. Although communities declare themselves to be diverse and open to entry, concrete actions are lacking. </p>
The non-cognitive skills in international studies: features and critical aspects
Authors: Nirchi Stefania 
Published: February 2023

Over the years, different definitions have accompanied the evolution of the non-cognitive skills concept. In this essay, we will analyse, in particular, their social-emotional dimension, through the Survey on Social and Emotional Skills (OECD, 2017); the features and critical aspects that have characterized their development and, if is it possible to separate cognitive and non-cognitive skills.

Le non-cognitive skills negli studi internazionali: peculiarità e aspetti critici.
Nel corso degli anni, diverse definizioni hanno accompagnato l’evoluzione del concetto di competenze non cognitive. In questo saggio analizzeremo in particolare: la loro dimensione socio-emotiva, attraverso l’indagine Social and Emotional Skills (OCSE, 2017); le peculiarità e gli aspetti critici che ne hanno caratterizzato lo sviluppo e se è possibile separare le competenze cognitive da quelle non cognitive.
Characteristics of Public Green Open Spaces and Efforts In Enhancing The Quality and Function Using Tri-Valent Approach: Case of Manado City, Indonesia
Authors: E.V Wuisang Cynthia , M Rondonuwu Dwight , L.E Sela Rieneke , Tilaar Sonny , Suryono Suryono 
Published: February 2023

Urban communities can feel more applicable benefits in urban environmental planning as part of their daily activities. Urban public open spaces have not all considered the quality of the environment. Initial observations show that the utilization of public open space is not yet optimal from environmental and social aspects. Manado City Public open space is a place of interaction and recreation for the community, but currently little attention is paid to ecological or environmental functions and the quality of the landscape. With the observed background, this study aims to examine the city's public open spaces that can improve their functions and quality, by providing ecological protection and aesthetic quality of the landscape. This study evaluates the performance of open spaces (Patches Landscape) that support the sustainability of recent urban environment. The approach in this study in addition to sustainable cities, sustainable landscapes also integrate environmental psychology, aesthetics and people's perceptions of urban open spaces. This research also looks at the historical aspects of the community that will give identity to the planned open spaces, and their impact on improving the ecology and quality of open spaces. This research is conducted in Manado City, Indonesia. The method used in this research is a mix-method approach using Trivalent concept. The concept is to evaluate the tree-in-one main dimensions namely ecological, socio-cultural and aesthetic in landscape planning and design. The analysis of Landscape Quality Indicators is used to establish the concept of an engineering and spatial-based urban public open space design model recommendation.
Análisis de la enseñanza de la alimentación en ciencias naturales para una vida saludable con estudiantes de educación básica desde la práctica docente
Authors: López-Botello Felisa Yaerim , Mendieta-Lagunas Mariana 
Published: February 2023

En los últimos años la educación alimentaria se volvió un tema de controversia, por su forma de ser vista por la sociedad de diversos países, generando el interés de distintas asociaciones tanto nacionales como internacionales, las cuales, se dieron a la tarea de investigar más a fondo lo que es la educación alimentaria y como se lleva a cabo su impartición en escuelas de educación básica.
Hablar de educación alimentaria lleva a una participación activa y permanente de docentes, directivos, padres de familia y estudiantes, considerando que el tema está vinculado a las ciencias naturales, que es impartida como materia en todas las escuelas de educación básica.
El presente trabajo, tiene por objetivo conocer la importancia de la enseñanza de la educación alimentaria, para una vida saludable con estudiantes de educación básica desde la práctica docente, además de formar un individuo consiente en la toma de sus decisiones de un consumo responsable para lograr una alimentación sana.
A través de un enfoque mixto, la realización de un diagnóstico socioeducativo y haciendo uso del instrumento del cuestionario aplicado a docentes y otro a estudiantes, se concluyó que actualmente en México existe una mala educación alimentaria por la falta de información, conocimiento y reflexión para una alimentación sana desde el aula.
También destaca la manera en como es impartida la educación alimentaria con estudiantes de educación básica, la cual no es la adecuada, considerando que no se cumple con el propósito de formar individuos consientes que logren una vida saludable a través de su alimentación.
AMBIENTE FAMILIAR POSITIVO, ANGUSTIA GENERAL Y EXPERIENCIAS POSITIVAS ANTE EL CONFINAMIENTO POR COVID-19 EN ADOLESCENTES
Authors: Gaxiola Romero José Concepción , Gaxiola Villa Eunice , Pineda Domínguez Antonio , Gonzáles Lugo Sandybell 
Published: February 2023

El propósito del presente estudio fue analizar la relación de la angustia y experiencias positivas con el ambiente familiar medido antes y durante el confinamiento por COVID19. Se probó un modelo de diferencia de puntaje latente para evaluar la relación entre el cambio latente en el ambiente familiar positivo, la angustia general y las experiencias positivas ante el confinamiento por COVID-19. Nuestra hipótesis se basó en la teoría transaccional del desarrollo psicológico donde el ambiente familiar positivo tendrá una relación positiva con las experiencias positivas ante la adversidad y una relación negativa con la angustia general frente al confinamiento por Covid-19. Participaron 111 estudiantes de educación preparatoria del noroeste de México (estudio longitudinal de dos tiempos), demostrando que el ambiente familiar positivo afectó positivamente a las experiencias positivas ante la adversidad. A la inversa, el ambiente familiar positivo tuvo un efecto negativo significativo sobre la angustia general. Se discute que el ambiente familiar positivo es relevante para los estudiantes adolescentes, ya que es posible que sustituya momentáneamente el aislamiento social provocado por la contingencia sanitaria por COVID-19. Se encontró que el ambiente familiar positivo previo al confinamiento se relacionó de forma positiva con las experiencias positivas ante la adversidad y de forma negativa con la angustia general. Similarmente, el incremento en el ambiente familiar positivo al momento del confinamiento se relacionó de forma positiva con las experiencias positivas ante la adversidad y de forma negativa con la angustia general
Economic component of the ecosystem services losses
Authors: Kolmakova Valentyna M. , Patoka Iryna V. 
Published: February 2023

The article is aimed at development of the scientific approaches as to assessment of the economic component of the ecosystem services losses at the local level.
An analysis is made of the components of the environmental economic index at the local level and the economic mechanism of formation of the ecosystem services losses is studied. It is emphasized that the ecosystem assessment of the environmental pollution losses at the local level is impossible without taking into consideration the up-to-date approaches as to the ecosystem development analysis and their state assessment. The ecosystem assets accounting while estimating the investment attractiveness of the territory is substantiated. Basing on the water resources, the management and economic approaches are specified while estimating losses of the ecosystem water services under management decentralization to prevent negative consequences of the economic activities at the local level. The necessity is substantiated to develop novel theoretical and methodological approaches to solve this problem envisaging three key aspects in particular, aiming at development of the theory of the ecosystem services losses based on losses (gaining no advantages) from the water ecosystem, development of the theory of ecological risk and that of the water ecosystem degradation. Conceptual scheme is proposed to determine parameters of the economic damage caused by the water ecosystem services losses.
The further long-term researches involve approaches as follows: to form an integrated strategic approach for implementation of the ecosystem analysis of the losses caused by the economic negative consequences at the local level; to develop and implement effective methodical approaches for assessment of the losses caused by the negative economic consequences to make the territory attractive for investment using local natural resources in particular, water, as environmental assets of the territory sustainable development.