bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sara Levy i jej muzyczna kolekcja. Koncerty klawiszowe Carla Philippa Emanuela Bacha z Biblioteki Narodowej 1
Authors: Görny Tomasz 
Published: March 2023

ABSTRACT

Sara Levy and Her Music Collection. Keyboard Concertos by Carl Philipp Emanuel Bach from the National Library ofPoland
The paper discusses musical sources kept in the National Library of Poland, namely a collection of handwritten copies of ten keyboard concertos by Carl Philipp Emanuel Bach, made by Georg Amft based on materials that originated from the music collections of Sara Levy and Zippora Wulff. This paper primarily focuses on the Concerto in A Minor Wq 26. Amft’s copy of that piece was likely made based on a Bach’s autograph kept in the Royal Library in Berlin (Königliche Bibliothek). Seeing as Amft’s Vorlage is now lost, the Warsaw document appears to be an important indirect source for an early version of Wq 26.
Molecular profiling of rare thymoma using next-generation sequencing: meta-analysis
Authors: Kostic Peric Jelena , Cirkovic Andja , Srzentic Drazilov Sanja , Samardzic Natalija , Skodric Trifunovic Vesna , Jovanovic Dragana , Pavlovic Sonja 
Published: March 2023

Abstract

Background
Thymomas belong to rare tumors giving rise to thymic epithelial tissue. There is a classification of several forms of thymoma: A, AB, B1, B2, B3, thymic carcinoma (TC) and thymic neuroendocrine thymoma. In this meta-analysis study, we have focused on thymoma using articles based on the disease’s next-generation sequencing (NGS) genomic profiling.

Materials and methods
We conducted a systematic review and meta-analysis of the prevalence of studies that discovered the genes and variants occurring in the less aggressive forms of the thymic epithelial tumors. Studies published before 12th December 2022 were identified through PubMed, Web of Science (WoS), and SCOPUS databases. Two reviewers have searched for the bases and selected the articles for the final analysis, based on well-defined exclusion and inclusion criteria.

Results
Finally, 12 publications were included in the qualitative as well as quantitative analysis. The three genes, GTF2I, TP53, and HRAS, emerged as disease-significant in the observed studies. The Odds Ratio for all three extracted genes GTF2I (OR = 1.58, CI [1.51, 1.66] p < 0.00001), TP53 (OR = 1.36, CI [1.12, 1.65], p < 0.002), and HRAS (OR = 1.02, CI [1.00, 1.04], p < 0.001).

Conclusions
According to obtained data, we noticed that the GTF2I gene exhibits a significant prevalence in the cohort of observed thymoma patients. Moreover, analyzing published articles NGS has suggested GTF2I, TP53, and HRAS genes as the most frequently mutated genes in thymoma that have pathogenic single nucleotide variants (SNV) and Insertion/Deletion (InDel), which contribute to disease development and progression. These variants could be valuable biomarkers and target points specific to thymoma.
Oral verrucous carcinoma: a diagnostic and therapeutic challenge
Authors: Kristofelc Nejc , Zidar Nina , Strojan Primoz 
Published: March 2023

Abstract

Background
Verrucous carcinoma is a low-grade variant of squamous cell carcinoma with specific morphologic, cytokinetic and clinical features. Despite low mitotic activity and slow growth, it can infiltrate adjacent tissues in advanced stages but does not metastasize. The most frequently affected site is the oral cavity. The following article provides latest updates in the etiology, clinical presentation, diagnostics and treatment options in oral verrucous carcinoma and discusses the existing dilemmas linked to this unique malignancy.

Conclusions
Oral verrucous carcinoma must be differentiated from conventional squamous cell carcinoma due to its less aggressive behaviour with a more favourable prognosis. Close communication between clinician and pathologist is mandatory for making a correct diagnosis. Primary surgery with negative surgical margins seems to be the most successful treatment. However, management recommendations are not uniform since they are mostly based on case reports and small retrospective case series. Prospective and pooled multi-institutional studies are therefore needed.
URGENSI PERENCANAAN PEMBENTUKAN PRODUK HUKUM DAERAH DALAM PENETAPAN PRODUK HUKUM DAERAH DI KABUPATEN CIAMIS
Authors: Aprillia Nova Elsa , Hidayat Deni Wahyu , Farida Ida , Mulyanti Dewi 
Published: March 2023

Untuk mengantisipasi agar produk hukum daerah tidak terjebak sebagai produk hukum yang cacat hukum dan dishasmonis, setiap pembentukan peraturan hukum daerah senantiasa harus memperhatikan konsep Negara hukum, asas demokrasi dalam pembentukan peraturan perundang-undangan, dan asas-asas umum perundang-undangan yang baik serta dilaksanakan secara terencana, terukur dan terintegrasi. Perencanaan pembentukan produk hukum daerah merupakan amanat Peraturan Menteri Dalam Negeri Nomor 80 Tahun 2015 yang harus diimplementasikan. Penelitian ini bertujuan untuk mempelajari, mengetahui, dan menganalisis Mekanisme Pembentukan Produk Hukum Daerah Di Kabupaten Ciamis, Urgensi Perencanaan Produk Hukum Daerah dalam Penetapan Produk Hukum Daerah Di Kabupaten Ciamis dan Analisis Normatif terhadap Urgensi Perencanaan Produk Hukum Daerah berdasarkan Peraturan Menteri Dalam Negeri Nomor 80 Tahun 2015 tentang Pembentukan Produk Hukum Daerah di Kabupaten Ciamis. Penelitian dan penulisan dilakukan dengan desain deskriptif dan memperoleh data melalui metode kualitatif dalam bentuk, observasi, wawancara semiterstruktur, dokumentasi. Digunakan metode analisis reduksi data, penyajian data dan penarikan kesimpulan.
Hasil penelitian bahwa Mekanisme Pembentukan Produk Hukum Daerah Di Kabupaten Ciamis dilaksanakan sesuai Undang-Undang Nomor 12 Tahun 2011 tentang Pembentukan Peraturan Perundang-undangan dan Peraturan Menteri Dalam Negeri Nomor 80 Tahun 2015 tentang Pembentukan Produk Hukum Daerah yaitu dengan prosedur pembentukan peraturan perundang-undangan yang mulai dari perencanaan, pembahasan, sinkronisasi dan harmonisasi hingga pada pembatalan dan pencabutan yang masing-masing tahapannya di laksanakan dengan Standart Operasional Prosedur yang berbeda, namun belum secara konsisten dan menyeluruh. Urgensi Perencanaan Produk Hukum Daerah dalam Penetapan Produk Hukum Daerah Di Kabupaten Ciamis merupakan pedoman utama dalam mewujudkan Pembangunan Daerah mengingat seluruh bagian Pelaksanaan Pembangunan Daerah merupakan implementasi dari produk hukum daerah itu sendiri. Perencanaan pembentukan produk hukum daerah menjadi pedoman sekaligus alat kendali untuk menekan adanya disharmonis peraturan perundang-undangan di daerah serta benturan hukum dan benturan kepentingan di daerah untuk memenuhi kebutuhan hukum di masyarakat.
APPRENTISSAGE ET MÉMOIRE : LES INSÉPARABLES DANS LE CERVEAU
Authors: Angéloz Aline 
Published: March 2023

Notre cerveau est plus que la somme de ses parties. Le quand, le où, et le comment des processus d'apprentissage et de mémoire impliquent encore de nombreuses hypothèses non-élucidées et donc qui doivent être investiguées. Comment le cerveau humain encode ses propres processus d'apprentissage et de mémoire et comment la topologie de son réseau social élargi présente des modèles neuronaux similaires aux modèles neuronaux de nos amis et de nos liens communautaires ?
Use of Cell Phones and Its Effect on Society
Authors: Khan Nasir , Aziz Faisal , Shabir Ghulam 
Published: March 2023

Purpose: Cell phone has become an important part of our lives. Everyone owns a cell phonewhether it is a child or an elder. Cell phones can perform almost every operation related to workoranything.Itisavailableforindividualsatanyplaceortime.Themainpurposeofourstudywasto find out how smart phones and their wide mix of features, have been making an impact on thesociety in case of their real-life interactions. It’s important to find out what’s the link between thesmartphonesandsocialinteractions.
Methodology:Thestudyincludeda12-questionsurveythataskedquestionsif the participants own a cell phone, about participants’ daily use of smartphones, including thehoursspentusingthem.Therewere26participantsinthestudy,amongthem50%weremalesand50%were females.The data obtainedfrom the surveywerecompiledintopie-charts.
Findings: The following conclusions were developed based on our research. The participants from age group between 16 and 20 are most affected socially with the use of cell phones. The participants from young age group have more daily usage of cell phones as compared to the elderly ones. The individuals from young age group mostly use smart phones as their means of entertainment while the elders use it for work and communication purpose. Most of the individuals think that cell phone has made their life easier.
Implications: The advancement of mobile technology has many uses but at the same time has been limiting individual’s ability because people totally rely on technology instead of challenging their brain.
TRACER STUDY PROGRAM STUDI S1-PENDIDIKAN TEKNIK ELEKTRO 2022
Authors: Agung Achmad Imam , Rahmadian Reza , Achmad Fendi , Z M Syariffuddien 
Published: March 2023

Kualitas layangan pendidikan dapat dilakukan melalui penilaian kinerja program studi oleh Badan Akreditasi Nasional Perguruan Tinggi dan penyusunan laporan Evaluasi Diri sebagai dasar pijakan konsolidasi organisasi dan pengembangan program kegiatan akademik. Salah satu butir evaluasi diri dan isian borang akreditasi ialah mengenai keberadaan lulusan setelah meninggalkan kuliah. Tujuan pada penelitian ini adalah untuk mengetahui penilaian alumni mengenai penyelenggaraan program studi, mengetahui penilaian alumni mengenai mutu layanan program studi; mengetahui penilaian stakeholders atas kinerja alumni, mengetahui lama masa tunggu alumni sampai mendapatkan pekerjaan, dan mengetahui relevansi antara kurikulum dengan kebutuhan di lapangan pada program studi S1 PTE. Jenis penelitian yang digunakan adalah kualitatif. Metode yang digunakan adalah survey dengan menggunakan quota sampling. Penelitian kualitatif dilaksanakan untuk menjelaskan, menguji hubungan antar fenomena dan menentukan kausalitas dari variabel-variabel. Hasil tracer study program studi S1 PTE telah menunjukkan bahwa karakteristik lulusan sebagian besar bekerja di bidang pendidikan baik di sekolah maupun lembaga kependidikan sebagai pendidik (52.3%). Input dari lulusan juga menunjukkan bahwa kurikulum/mata kuliah yang mereka dapatkan ketika masih kuliah sangat relevan dengan pekerjaan mereka sekarang, walaupun untuk kedepan perlu ada beberapa kompetensi tambahan terutama softskill yang perlu dikembangkan. Tingkat daya saing lulusan yang ditunjukkan melalui waktu tunggu yang relatif singkat untuk mendapatkan pekerjaan pertama. Waktu tunggu lulusan program Studi S1 PTE 84.1% kurang dari 6 bulan, artinya tidak perlu menunggu lama bagi lulusan program studi S1 PTE untuk mendapatkan pekerjaan pertamanya. Relevansi pekerjaan dengan program studi juga menunjukkan kondisi yang positif dimana sebagian besar lulusan menjadi guru (93.2%) sesuai dengan yang dipelajari selama perkuliahan. Hal tersebut juga didukung tingginya tingkat kepuasan pengguna terhadap kinerja lulusan. Sebanyak 79.1% pengguna menyatakan puas dan 20.9% menyatakan sangat puas terhadap kinerja lulusan program studi S1 PTE.
ANALYTICAL TOOLS FOR ASSESSING THE RELIABILITY OF COUNTERPARTIES
Authors: Bank Sergey 
Published: March 2023

Entrepreneurs quite often work with organizations that provide services of various kinds. It is also quite important how reliable the counterparty is and what kind of business reputation he has, the effectiveness of cooperation with him also depends on this. In this regard, it is necessary to check the counterparties both before the start of cooperation and in the process. These measures enable the company to protect itself from the dissatisfaction of the tax inspectorate, additional financial expenses.
In this article we will look at various ways of checking subjects, because in practice a large number of entrepreneurs have questions in finding and verifying counterparties. The article will describe what information needs to be analyzed during verification, which services to use for verification.
Anthologie de littérature mondiale en français et littératures africaines : quelques réflexions à partir du Livre du Pays noir. Anthologie de littérature africaine (1927) de Roland Lebel
Authors: Aggarwal Kusum 
Published: March 2023

L’élaboration d’une anthologie mondiale des littératures africaines représente, à mon sens, une conjoncture opportune pour revisiter l’histoire littéraire africaine pour la recentrer et la repenser dans ses relations avec le cadre dans lequel elle s’est constituée dans le continent africain. L’anthologie de Roland Lebel Le Livre du pays noir (1927), rééditée ensuite dans la collection de Roger Little (L’Harmattan, Autrement mêmes) représente, à cet égard, un jalon. Car, au-delà de son parti-pris colonial, il pointe la complexité du canon africain formé à l’intersection des pratiques littéraires extranationales, voire transnationales.
L’essai procède en étude en trois temps. Il ouvre avec une lecture croisée de la colonisation et de la mondialisation, tournants cruciaux de la dénationalisation littéraire ; et cerne ensuite, à partir d’une lecture d’une série d’anthologies coloniales et postcoloniales, les évolutions et les transformations de l’idée que l’on se faisait de la littérature africaine ; pour clore, enfin, sur une enquête sur ce que disent les critiques littéraires des relations entre ces deux pôles littéraires. On aura saisi ainsi l’importance de la prise en compte du processus historique de l’élaboration de la littérature monde dès lors qu’il s’agit de concevoir une anthologisation mondiale des littératures africaines.
CORRUPÇÃO NO VICE-REINADO DA NOVA ESPANHA: UMA TERCEIRA TENTATIVA DE VALORAÇÃO
Authors: Pietschmann Horst 
Published: March 2023

Partindo de reflexões sobre a corrupção na atualidade, busca-se rastrear o desenvolvimento da historiografia sobre a corrupção na Nova Espanha, tanto com base em estudos próprios anteriores como com referência à ampliação da problemática durante o decênio passado. Como conclusão, afirma-se que frente a desenvolvimentos da historiografia sobre o Império do México é preciso recolocar a fundo a problemática com um enfoque mais amplo, para comprovar se os problemas atuais não são mais que uma repetição de fenômenos históricos à luz da globalização.
Frederico Paganin Gonçalves, Bolsista do Baden-Württemberg Stiftung (Tradução)

Graduando em Direito, UFRGS; bolsista do Baden-Württemberg Stiftung, em período de mobilidade acadêmica na Ruprecht-Karls-Universität Heidelberg
Alfredo de J. Flores, Professor Permanente do PPGD-UFRGS, RS, Brasil (Revisão)

Professor Permanente do PPGD-UFRGS, RS, Brasil
Uso de Anticonceptivos Orales y Percepción del Papel del Farmacéutico Comunitario entre Adolescentes: un estudio observacional
Authors: Valle Velasco Betsy , Zarzuelo Romero Maria Jose , Valverde Merino Maria Isabel , Martinez Martinez Fernando 
Published: March 2023

Introducción: Los embarazos no deseados en adolescentes tienen graves consecuencias tanto para las propias adolescentes y sus bebés como para el uso de los recursos del sistema sanitario. Una de las razones es el escaso uso de píldoras anticonceptivas orales (ACO) entre esta población, debido principalmente a la falta de información o a la no adherencia a los medicamentos. El objetivo de este estudio fue describir la información que reciben las adolescentes sobre los ACO y su uso, así como su percepción del papel del farmacéutico comunitario en este campo.
Método: Se realizó un estudio observacional transversal mediante encuesta, aplicada a mujeres entre 12-19 años residentes en España, independientemente de si habían utilizado o no ACO, durante abril de 2021. Para la difusión de esta encuesta se utilizaron diferentes redes sociales. Asimismo, se contactó con diferentes asociaciones españolas dedicadas a la orientación de la planificación familiar y la salud sexual en adolescentes.
Resultados: El 81,7% (n=76) de los encuestados no había tomado ACO, aunque el 35,5% (n=33) sí había mantenido relaciones sexuales. El 6% (n=1) que tomaba o había tomado ACO informó que eran adherentes. El 88% (n=82) pensaba que el farmacéutico tiene conocimientos sobre medicamentos; sin embargo, sólo el 19,4% (n=18) les consultaría para resolver dudas sobre ACO.
Conclusiones: Para resolver los problemas de falta de información sobre ACO y de adherencia en mujeres adolescentes, el farmacéutico comunitario es un profesional accesible que puede contribuir a ello adoptando una actitud activa y utilizando diferentes formas de material educativo.
Antagonistic effect of mepyramine and tubocurarine on the histamine-mediated contraction of intestinal smooth muscle cells
Authors: Salvatierra Baldeón Andree 
Published: March 2023

Introduction: Histamine is an endogenous ligand which exerts its biological actions by binding to 4 subtypes of histamine receptors (HR). Its effects on the gastrointestinal tract are complex being the dominant effect contraction of muscle cells.
Method: The aim of this study was to verify the antagonistic effect of mepyramine (10-10M - 10-7M) and tubocurarine (10-7M - 10-4M) in the contractile action of histamine (10-11M - 10-4M). in guinea pig ileum, for this purpose it was used the program Virtual Organ Bath 16 V 2.8, which allow quantify the change in strength(g) produced by smooth muscle contraction in the presence of these substances. Concentration-response curves were obtained through GraphPad Prism® graphic program. The determination of the competitive nature of the antagonist and the calculation of the affinity constant was performed through Schild method.
Results: Mepyramine is a competitive antagonist of histamine (10-10M to 10-7M), making it a potential therapeutic agent for the treatment of irritable bowel syndrome. On the other hand, it is not understood that tubocurarine is an antagonist of histamine receptors.
Conclusions: The results obtained provide evidence that the contractile effect of histamine on the smooth muscle of intestinal cells isolated from guinea pig is competitively antagonized by mepyramine. In addition, by calculating the pKB parameter, it was found that this compound has greater potency than other antihistamines.
Creatividad, habilidades sociales y comportamiento prosocial en adolescentes: diferencias según sexo
Authors: González Moreno Alba , Molero Jurado María del Mar 
Published: March 2023

El desarrollo de variables como la creatividad o las habilidades sociales puede favorecer el incremento de las conductas prosociales en el alumnado adolescente. Este tipo de competencias pueden verse alteradas según el sexo de los jóvenes. El objetivo principal de esta investigación es examinar si existen diferencias significativas en creatividad, habilidades sociales y conductas prosociales entre los chicos y chicas adolescentes.
Un total de 743 estudiantes de entre 14 y 19 años pertenecientes a distintos centros educativos han participado en este estudio. Los instrumentos utilizados han sido el Cuestionario de Creatividad de Turtle (CCT), el Cuestionario de Habilidades Sociales (CHASO) y el Cuestionario de Conducta Prosocial (CCP).
Los resultados obtenidos indican que no existen diferencias relacionadas con la creatividad entre ambos grupos de adolescentes, pero sí se encuentran dichas diferencias en las variables de habilidades sociales y conductas prosociales. Las chicas adolescentes puntúan más alto en las dimensiones referidas a las habilidades sociales de expresar sentimientos positivos, afrontar las críticas y pedir disculpas, mientras que los chicos tienen mayor nivel en habilidades sociales total y sus dimensiones de interactuar con las personas que me atraen, mantener la calma ante las críticas, hablar en público / interactuar con superiores y afrontar situaciones de hacer el ridículo. En cuanto a las conductas prosociales, las chicas destacan en empatía y respeto, mientras que los chicos se encuentran más implicados en las relaciones sociales.
En definitiva, esta investigación muestra las diferencias según el sexo en variables que ayudan a los adolescentes a desarrollarse de manera positiva.
COOKIES E BEHAVIORAL ADVERTISING: UMA ANÁLISE DO DEVER DE INFORMAÇÃO E A RELAÇÃO COM A LGPD
Authors: Alberton Coutinho Silva Cecília , Linden Ruaro Regina 
Published: March 2023

Cookies são pequenos arquivos de texto simples enviados ao navegador utilizado pelo usuário, por meio dos quais o site armazena todas as informações relacionadas à navegação, tornando a experiência do usuário mais personalizada do ponto de vista das suas preferências. O presente artigo busca analisar, sem ter a pretensão de esgotar a matéria, como se dá o dever de informação e a relação existente com a LGPD para fins de publicidade comportamental e uso de cookies. Para esse fim, a estudo será dividido em três partes, para analisar (i) a relação entre cookies e a publicidade comportamental (ou bahavioral advertising); (ii) o dever de informação no mercado de consumo; e (iii) a relação entre o CDC e a LGPD, no esforço de demonstrar que o uso de cookies perpassa, necessariamente, o cumprimento de requisitos legais previstos em ambas as legislações. Ao final, se concluirá no sentido de que as disposições do CDC e da LGPD são complementares e que boas práticas são fundamentais no contexto de publicidade comportamental, sem prejuízo de novas regulamentações. Utilizou-se o método indutivo e de interpretação jurídica pautado na coleta e análise de bibliografia, legislações e de jurisprudência na matéria. O trabalho é orientado por uma pesquisa empírica, pois as respostas da problemática são encontradas e analisadas na realidade social.