bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multisensory perceptual learning in virtual reality may facilitate transfer to untrained locations but is impacted by training procedures
Authors: Fromm Catherine A. , Huxlin Krystel R. , Maddox Ross K. , Polonenko Melissa J. , Diaz Gabriel J. 
Published: May 2023

AbstractVisual training improves performance in visually-intact and visually-impaired participants, making it useful as a rehabilitation tool. An interesting question in rehabilitation is whether invocation of multisensory integration could increase training efficacy. To investigate, participants completed a 10-day training experiment wherein they repeatedly performed a 4-way global motion direction discrimination task. On each trial, participants were presented with a 5° diameter visual global motion stimulus placed in a gaze-contingent manner at 10° azimuth/elevation. The visual-only group was presented the unimodal visual stimulus. However, for the auditory/visual (AV) group, the visual stimulus was paired with a pulsed white-noise auditory cue moving along in a direction consistent with the horizontal component of the visual motion stimulus. Direction range thresholds (DRT) were computed daily. The motion direction discrimination learning transferred fully in both groups, regardless of the presence of a feature-based attention cue. However, the figure-ground segregation learning only fully transferred to untrained locations with the addition of the feature-based attention cue. These results speak to the multiple levels of processing on which perceptual learning can operate.PACS0000, 11112000 MSC0000, 1111
Reusable rule-based cell cycle model explains compartment-resolved dynamics of 16 observables in RPE-1 cells
Authors: Lang Paul F. , Penas David R. , Banga Julio R. , Weindl Daniel , Novak Bela 
Published: May 2023

AbstractThe mammalian cell cycle is regulated by a well-studied but complex biochemical reaction system. Computational models provide a particularly systematic and systemic description of the mechanisms governing mammalian cell cycle control. By combining both state-of-the-art multiplexed experimental methods and powerful computational tools, this work aims at improving on these models along four dimensions: model structure, validation data, validation methodology and model reusability.We developed a comprehensive model structure of the full cell cycle that qualitatively explains the behaviour of human retinal pigment epithelial-1 cells. To estimate the model parameters, time courses of eight cell cycle regulators in two compartments were reconstructed from single cell snapshot measurements. After optimisation with a parallel global optimisation metaheuristic we obtained excellent agreements between simulations and measurements. The PEtab specification of the optimisation problem facilitates reuse of model, data and/or optimisation results.Future perturbation experiments will improve parameter identifiability and allow for testing model predictive power. Such a predictive model may aid in drug discovery for cell cycle-related disorders.Author SummaryWhile there are numerous cell cycle models in the literature, mammalian cell cycle models typically suffer from four limitations. Firstly, the descriptions of biological mechanisms are often overly complicated yet insufficiently comprehensive and detailed. Secondly, there is a lack of experimental data to validate the model. Thirdly, inadequate parameter estimation procedures are used. Lastly, there is no standardized description of the model and/or optimization problem.To overcome these limitations, we combine best-in-class technology to address all four simultaneously. We use a rule-based model description to provide a concise and less error-prone representation of complex biology. By applying trajectory reconstruction algorithms to existing data from highly multiplexed immunofluorescence measurements, we obtained a rich dataset for model validation. Using a parallel global metaheuristic for parameter estimation allowed us to bring simulations and data in very good agreement. To maximize reproducibility and reusability of our work, the results are available in three popular formats: BioNetGen, SBML, and PEtab.Our model is generalizable to many healthy and transformed cell types. The PEtab specification of the optimization problem makes it straightforward to re-optimize the parameters for other cell lines. This may guide hypotheses on cell type-specific regulation of the cell cycle, potentially with clinical relevance.
Circulating Microparticles: Optimization and Standardization of Isolation Protocols and Reassessment of Their Characteristics and Functions
Authors: Zhang Chen , Hu Jiajia , Shi Yifan , Feng Yang , Li Zeyang , Zhang Tianyu , Hong Liwen , Dong Zi , Tang Yiding , Wang Zhengting , Ning Guang , Huang Guorui 
Published: May 2023

AbstractMicroparticles (MPs) are convenient for clinical diagnosis, and have functional roles in signal transduction. Although the importance of MPs is being increasingly recognized, the diversity of isolated protocols for MPs results in a heterogeneous population of their unknown origins, even expands to uncertain functions. Here we systematically studied the composition of MPs at different centrifugal speed intervals, and found that 3000g was a critical centrifugation speed in determining new MPs composition. The platelet-derived particles accounted for more than 80% under 3000g, while only about 20% in MPs obtained over 3000g. Furthermore, we found that the function of new MPs was significantly different from that of traditional ones, such as procoagulation activity, anti-inflammation and clinical diagnosis etc. Thus, our work optimized the method of MPs isolation, clarified some characteristics and physiological functions that should belong to platelets rather than MPs, which will derive new conceptual MPs for its composition and function.
COVID-19 vaccination at a hospital in Paris: spatial analyses and inverse equity hypothesis
Authors: Valéry Ridde , Gaëlle André , Olivier Bouchaud , Emmanuel Bonnet 
Published: May 2023

AbstractBackgroundVaccination against SARS-CoV-2 has been deployed in France since January 2021. Evidence was beginning to show that the most vulnerable populations were the most affected by COVID-19. Without specific action for different population subgroups, the inverse equity hypothesis postulates that people in the least deprived neighbourhoods will be the first to benefit.MethodsWe performed a spatial analysis using primary data from the vaccination centre of the Avicenne Hospital in Bobigny (Seine-Saint-Denis, France) from January 8th to September 30th, 2021. We used secondary data to calculate the social deprivation index. We performed flow analysis, k-means aggregation, and mapping.ResultsDuring the period, 32,712 people were vaccinated at the study centre. Vaccination flow to the hospital shows that people living in the least disadvantaged areas were the first to be vaccinated. The number of people immunized according to the level of social deprivation then scales out with slightly more access to the vaccination centre for the most advantaged. The furthest have travelled more than 100 kilometres, and more than 1h45 of transport time to get to this vaccination centre. Access times are, on average, 50 minutes in February to 30 minutes in May 2021.ConclusionThe study confirms the inverse equity hypothesis and shows that vaccination preparedness strategies must take equity issues into account. Public health interventions should be implemented according to proportionate universalism and use community health, health mediation, and outreach activities for more equity.
Short-term health system responses to epidemics across hard-to-reach areas in sub-Saharan Africa: A scoping review protocol
Authors: Murunga Annette A. , Ngoye Ben , Wafula Francis P. , Kokwaro Gilbert O. 
Published: May 2023

AbstractBackgroundEpidemics and disease outbreaks are the occurrence of cases of disease in excess of what would be normally expected. Epidemic-prone diseases, including emerging and re-emerging diseases, constitute the greatest threat to public health security and disruption of social and economic development. When cases of epidemics are diagnosed in specific areas, an outbreak response is triggered to stop the spread swiftly, keeping as few people as possible from being infected. In the past 20 years, the sub-Saharan region has witnessed a marked increase in the number of outbreaks in pandemics, such as cholera, dengue, A/H5N 1 influenza, and rift valley fever, among others. And while many of the efforts toward containment have been individually studied, we have no recent studies that examine them collectively in order to draw appropriate comparisons, no recent studies that have especially focused on hard-to-reach areas, and none that have applied a health systems lens. This study thus details a scoping review of short-term health system responses to epidemics across hard-to-reach areas in sub-Saharan Africa.MethodsA scoping review will be undertaken following PRISMA guidelines for scoping reviews. A modified Donabedian framework will be used to help in understanding approaches used in the immediate health system responses to disease outbreaks. The review will focus on published and unpublished studies that report short-term health systems responses during disease outbreaks in sub-Saharan Africa. These will be gleaned from PubMed, google scholar and Cochrane electronic databases, supplemented by a Google advanced search. In addition, manual searches will be carried out through related articles and websites. Two authors will independently screen the studies and extract data. Disagreements will be resolved by discussions, and a third reviewer will decide if there is no consensus. Data will be charted, coded, and narratively synthesized.OutcomeWe anticipate developing a document that will show the different approaches health systems responded with to epidemics in the short term and that will contribute to strengthening future short-term responses to disease outbreaks by identifying best practices and innovative ideas. In addition, the study will highlight possible knowledge gaps that need to be filled with new research.
Non-local model of chemotaxis based on peer attraction
Authors: Dupuy Lionel , Mimault Matthias , Ptashnyk Mariya 
Published: May 2023

AbstractMovement is critical for bacterial species inhabiting soils because nutrient availability is limited and heterogeneously distributed both in space and time. Recent live microscopy experiments show that bacteria form flocks when navigating through porous medium, and complex cell-cell interactions may be required to maintain such flocks. Here we propose a non-local model to study how peer attraction can affect flocking patterns in a porous medium. We establish the existence and uniqueness of the solution of the problem, propose a numerical scheme for simulations of the non-local convection-diffusion equation, and investigate the numerical convergence of the scheme. Numerical simulations showed that the strength of peer attraction is critical to control the size, shape, and nature of movement of the flocks in a porous network.MSC Classification35F31, 92Cxx, 92-10
Varied corrosion evolution behavior of pure Mg, AZ31 and AZ91 magnesium alloys in phosphate buffer solution
Authors: Li Mengmeng , Chen Jian , Sun Jingtao , Hao Long , Wu Di , Wang Jianqiu , Ke Wei 
Published: May 2023

Purpose
The purpose of this study is to investigate the initial corrosion behavior of pure Mg, AZ31 and AZ91 alloys in phosphate buffer solution (PBS) and to characterize the features in corrosion type and resistance of the corrosion product layer.

Design/methodology/approach
The scanning electron microscopy, equipped with energy-dispersive spectroscopy, X-ray photoelectron spectroscopy and electrochemical impedance spectroscopy have been used to characterize the as-corroded samples. Besides, the Mg2+ concentration in PBSs has been determined by inductively coupled plasma atomic emission spectrum.

Findings
It has been found that pure Mg suffers pit corrosion, and AZ31 initially undergoes pit corrosion and then uniform corrosion dominates with an extended immersion duration. However, AZ91 exhibits the uniform corrosion with the highest corrosion rate among the three materials. Besides, the corrosion product layer on AZ31 has the best compactness and corrosion resistance.

Originality/value
The findings add depth in understanding the corrosion of pure Mg and its alloys in PBS and also have guiding significance in exploring the effects by alloyed elements to develop new biomaterials with better performance.
What drives or inhibits consumers' preference to consume quietly?
Authors: Song Sigen , Wang Hengqin , Wang Cheng Lu 
Published: May 2023

PurposeSecret consumption refers to consumption of a product in a private situation, with the intent or behavior of hiding the consumption from others. This study contributes to the secret consumption literature by identifying the antecedents of secret consumption along with the explaining mechanism and boundary condition.Design/methodology/approachAn online study with experiment design was conducted to examine the impact of extroversion/introversion, self-presentation and product scarcity on secrete consumption.FindingsThe results show that consumer extraverted disposition and the self-presentation motive negatively influence secret consumption intention and suggest this relationship is explained by the self-presentation need. The findings also revealed that perceived product scarcity attenuated the negative impact of extraversion and self-presentation on secret consumption intention.Research limitations/implicationsThe findings provide interesting insights into advertising and retailing. In recognizing that secret consumption is a prevalent phenomenon in consumer behavior that may improve actual consumer product evaluation and preference, retailers or brand managers may encourage consumers to consume secretly.Originality/valueThis empirical study is a first attempt to explore the antecedents, mediating mechanism and boundary condition of consumer intention to engage in secrete consumption. The findings of the study provide important implication to theoretical development and managerial applications in advertising and retailing.
How cultural leadership ideals shape entrepreneurship?
Authors: Aziz Miriam R. , Salloum Charbel 
Published: May 2023

PurposeThe purpose of this study is to examine the influence of culturally endorsed implicit leadership theories (CLTs), specifically the cultural assumptions regarding ideal leadership, on individual entrepreneurship within the context of Lebanese culture. This paper investigates the relationship between culture and entrepreneurship by incorporating cultural values such as uncertainty avoidance and in-group collectivism, cultural practices and two types of CLTs: self-protective and charismatic. By exploring these factors, this study aims to gain a deeper understanding of the role of culture in shaping entrepreneurial behavior.Design/methodology/approachAs a fundamental quantitative research, this study used a snowball sampling method to collect primary data from 118 Lebanese entrepreneurs, avoiding selection biases. Three models were used, relevant to nascent entrepreneurship, new entrepreneurship and old entrepreneurship, and the data was analyzed using logistic regression analysis and likelihood ratio tests.FindingsThe findings indicate that there is a correlation between CLTs, cultural values and practices and individual entrepreneurship. However, this study did not find evidence of a causal relationship between cultural values and individual entrepreneurship through the mediating role of self-protective and charismatic CLTs.Practical implicationsThe research findings shed light on the beneficial synergy between cultural leadership ideals and individual entrepreneurship in the Lebanese context, providing a closer and more productive approach to studying entrepreneurship and leadership. From a managerial standpoint, these results have important implications for promoting entrepreneurship among various stakeholders, including educators, policymakers and support organizations.Originality/valueThis study differs from previous research by examining a country that demonstrates high levels of entrepreneurial awareness and involvement despite its unstable political and economic conditions.
Examining high-performance work practices in academia: role of administrative workload and support staff
Authors: Aparna S.M. , Sahney Sangeeta 
Published: May 2023

PurposeThe study aims to explore the effectiveness of performance-oriented practices like high-performance work practices (HPWPs) in higher education (HE), given its explicit focus on performance these days.Design/methodology/approachThe study uses hierarchical linear modeling using statistical package for social sciences (SPSS 22.0) to test the hypotheses. An intertwined framework of the ability–motivation–opportunity (AMO) model and the job demand-resources (JD-R) model was proposed. The study considered strategic hiring, recognition and participatory decision-making as ability, motivation and opportunity-enhancing practices respectively. Further, the study addressed the impact of institutional level moderators, like administrative workload (AWL) and support staff (SS).FindingsThe findings based on the responses of 385 faculties and 443 students from 36 Indian institutes, indicated that HPWPs enhanced the education performance (EP) of HE institutes. Further, results revealed that both AWL and SS had differential effects on the relationship between HPWPs and EP. Contrary to authors’ expectations, SS showed a negative effect of the relationship between HPWPs and EP.Research limitations/implicationsThe increased AWL was debilitating the beneficial effects HPWPs. The negative interaction effect of SS sheds light on the hidden issues surrounding SS in HE institutes. Based on findings, the study offered important theoretical and practical implications.Originality/valueTo the best of authors’ knowledge, the impact of innovative human resource (HR) practices in academia remains relatively under-researched, and the current study is an attempt to fill this void.
Critical incidents and supplier satisfaction - investigating tipping points in a seller’s market
Authors: Janssens Kim , Gelderman Cees J. , Petersen Jordy 
Published: May 2023

PurposeThe main purpose of this research is exploring the tipping points for a radical shift in supplier (dis)satisfaction. This study identifies triggers and links them to consequences for the buyer–supplier relationship.Design/methodology/approachThe Critical Incident Technique (CIT) was used to interview Dutch supplier representatives in the infrastructure sector, resulting in rich descriptions of 29 critical incidents, extracting first-hand information.FindingsSafety issues, technical disputes and recruitment of supplier’s technical staff have been identified as tipping points for suppliers to become dissatisfied. Implementing performance-based contracting is another critical incident that caused irritation and disappointment. On a more operational level, dissatisfaction was provoked by tender errors and price discussions with the buyer. This study also identified tipping points by which dissatisfied suppliers abruptly turned into satisfied suppliers. The effect of a solution-oriented buyer intervention appears to be most powerful if this behaviour transcends prior expectations.Practical implicationsConsequences of misunderstandings and discussion between supplier and buyer may be manageable or repairable, depending on the causes and triggers that influenced a supplier’s dissatisfaction. An early warning system could prove its worth, so that buyers are not faced with unpleasant surprises.Originality/valueDespite the growing number of studies, processes of how antecedents lead to supplier (dis)satisfaction are not well understood. Antecedents are predominantly investigated by cross-sectional survey data, giving little insights into micro-processes and actual interaction between buyers and suppliers. Although CIT has been applied in many disciplines, the technique is hardly used within the context of purchasing and supply management research.
Against all odds: women's motivation to become STEM entrepreneurs in Sri Lanka
Authors: Adikaram Arosha , Razik Ruwaiha 
Published: May 2023

PurposeThis paper aims to explore the motivations behind women in a developing South Asian country – Sri Lanka – to embark on entrepreneurship in science, technology, engineering and mathematics (STEM) fields, which is a doubly masculine hegemony operating within a culturally nuanced gendered context.Design/methodology/approachThe study employs a qualitative research approach, conducting in-depth semi-structured interviews with 15 STEM women entrepreneurs, following the theoretical lenses of push and pull motivation theory and gender role theory.FindingsAlthough the motivations of STEM women entrepreneurs cannot be exclusively categorized as either push or pull factors, the pull factors had a greater influence on the participants in motivating them to become entrepreneurs. The primary motivators for starting businesses in STEM were: inspiration from something or someone, inner calling, the identification of business opportunities, the need for flexibility, necessity and/or desire to help society. It was often difficult to identify one dominant motivator in many instances, as many factors were interlinked to motivate women to start a business. The study also revealed that gender ideologies could stifle the participants' motivation, while the inner need to break these gender ideologies implicitly stimulated their motivation.Originality/valueThe study contributes to and expands the knowledge of STEM women entrepreneurs in general and to the limited existing knowledge of STEM women entrepreneurs in developing countries specifically. The paper brings contextual novelty as Sri Lanka produces more female STEM graduates than men, which is unique compared to most other parts of the world.
Trade war, media tone and market reaction asymmetry
Authors: Zhang Wenjia , Du Julan 
Published: May 2023

Purpose
This study investigates the impacts of Chinese media reporting strategy (media tone) on the market performance of US-trade-intensive firms vs non-US-trade-intensive firms and the effect of media tone on the occurrence of good and bad news.

Design/methodology/approach
News texts were retrieved from nine major financial/economic media outlets. Lexical analysis and event study have been adopted to examine the impact of different types of news during the US–China trade frictions on Chinese firms.

Findings
The results show that US-trade-intensive firms vs non-US-trade-intensive firms exhibited different reactions to media coverage. US-trade-intensive firms care more about the governmental attitudes toward the trade war and potential policy supports implied in the official media reports than non-US-trade-intensive firms do. The return-chasing behavior hypothesis is supported by US-trade-intensive investors, and this effect is further enhanced when multiple releases occur on the same day. A higher media tone combined with intensified media releases significantly increases the volatilities of both US-trade-intensive and non-US-trade-intensive firms.

Practical implications
Information provided by this study helps the regulatory authorities to formulate measures to enhance investor confidence and better optimize resource allocation.

Originality/value
This study investigates the asymmetric effect of media tone on US-trade-intensive firms vs non-US-trade-intensive firms, which has not been examined, to the best of the authors’ knowledge, in the existing literature.