bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optical soliton solutions of dispersive Schrödinger-Hirota equation with chromatic and inter-modal dispersion in a couple of law medium
Authors: Onder Ismail , Esen Handenur , Secer Aydin , Ozisik Muslum , Bayram Mustafa 
Published: March 2023

Abstract
In this paper, the dispersive Schrödinger-Hirota equation with Kerr and parabolic laws in the presence of chromatic and intermodal dispersions were investigated for the first time. The Sinh-Gordon equation expansion method (ShGEEM) was used to get analytical optical solutions of the models. As a result of the application, dark, bright, kink and singular soliton solutions were obtained. 3D, 2D and contour plots of the obtained results were depicted. In addition, the effect of the changing parameter on the wave behavior was investigated and simulated by 2D plots. Due to the fact that the method is applicable and easy to use, no restrictions were encountered. It can be emphasized that the obtained soliton solutions and parameter analyses are innovative for the related investigations in the literature.
Sequential decomposition of discrete-time partially observed mean-field games
Authors: Vasal Deepanshu 
Published: March 2023

Abstract
We consider both finite and infinite horizon discounted mean-field games with imperfect observations where there is a large population of homogeneous players sequentially making strategic decisions and each player is affected by other players through an aggregate population state. Each player has a private state that she doesn’t perfectly observe but rather makes noisy observations about it. We first define a private belief stateof a player that is her belief on her own type given her information till time t and a joint common state on an archetypical player’s type and her private belief. Mean-field equilibrium (MFE) is then defined as a solution of coupled Bellman dynamic programming backward equation and Fokker Planck forward equation, where a player’s strategy in an MFE depends on both, her private belief state and current joint common state. In this paper, we present a novel backward recursive algorithm to compute all MFEs of the game. Each step in this algorithm consists of solving a fixed-point equation. We provide sufficient conditions that guarantee the existence of this fixed-point equation for each time t.
Anxiety and depression among caregivers of pediatric patients with tic disorder in western China: a hospital-based cross-sectional study
Authors: Liu Zheng , Yang Chunsong , Yu Dan , Zeng Linan , Jia Zhi-Jun , Cheng Guo , Zhang Lingli 
Published: March 2023

Abstract
Purpose: This study aimed to investigate the prevalence and potential influencing factors of anxiety and depression among caregivers of Chinese pediatric patients with TD.
Methods: A cross-sectional study was carried out on caregivers of pediatric patients with TD at a women’s and children’s hospital in western China from January to June 2021. A structured questionnaire was designed to collect data. Anxiety and depression were assessed using the self-rating anxiety scale (SAS) and self-rating depression scale (SDS), respectively.
Results: A total of 318 participants were included in this study, with a response rate of 89.58% (318/355). The average age of pediatric patients with TD was 8.38 ± 2.54 years, and 78.30% (249/318) of caregivers were aged between 30-50 years old. Overall, 14.78% (47/318) of caregivers presented the symptom of anxiety, with a mean SAS score of 54.81±5.26, and 19.81% (63/318) of caregivers presented the symptom of depression, with a mean SDS score of 59.64±5.83. Furthermore, logistic regression analysis revealed that the common family relationship and solitary pediatric patients were significantly associated with anxiety in caregivers of pediatric patients with TD, as well as the single-parent family, mistaken cognition of TD, and fewer friends of pediatric patients were significantly associated with depression.
Conclusions: Anxiety and depression are prevalent among caregivers of TD pediatric patients, which brings up the importance of psychiatric support for this group. Longitudinal studies need to be conducted to further confirm the causality before interventions to improve mental health are developed.
Synergistic antimicrobial system based on nisin and α-hydroxy acid
Authors: Guo Hui , Zhao Fengju , Lei Bingshuang , Yang Wei , Guo Lili , Qian Junqing 
Published: March 2023

Abstract
Synergistic antimicrobial is a promising way to overcome microbial contamination in food and drugs. In the study, the synergistic effect between nisin and each α-hydroxy acid on E. coli and S. aureus was investigated. The experimental results showed that the combined antibacterial ability of nisin-citric acid system was the most prominent. The FCI index also indicated that the combination of nisin and citric acid had synergistic effects on E. coli. When nisin was combined with citric acid, the inhibition rates of E. coli and S. aureus were increased to 4.43 and 1.49 times, respectively. Nisin-citric acid complex system could effectively slow down the proliferation of S. aureus and E. coli at lower concentrations, and can quickly destroy the cell membrane after 4 hours of action. Therefore, the combination of nisin and citric acid is expected to be a potential solution for food and drug preservation.
Impact of therapeutic and prophylactic anticoagulation after soft tissue tumor resection and microsurgical defect coverage in patients with high-risk coagulopathies or vascular diseases
Authors: Daniel Bassem W. , Thielmann Julien , Dragu Adrian , Alawi Seyed Arash 
Published: March 2023

Abstract

Introduction: The wide resection and microsurgical free flap coverage are main pillars of the multimodal treatment of soft tissue malignancies. In the challenging subpopulation of patients with preexisting hypercoagulabilities or documented vascular diseases, perioperative bridging anticoagulation is advised, which is considered by some surgeons as challenging. The authors investigate the outcomes and complication in this subpopulation shedding light on prophylactic and therapeutic anticoagulation.
Material and Methods: A retrospective, monocentric evaluation of all patients with malignant soft tissue tumors undergoing tumor resection and defect reconstruction was performed from 2005 to 2021 in a comprehensive cancer care center for soft tissue tumors. The main inclusion criterium was preoperative anticoagulation therapy due to documented cardiovascular comorbidities or coagulopathies. Bridging was performed with an alternative anticoagulation regimen, either prophylactic or therapeutic. The demographics, bridging regimens, outcomes and complications are reported and compared between the two bridging groups.
Results: Out of 240 soft tissue tumor patients receiving reconstructive microsurgical coverage 26 patients received 29 free flaps. Of these, 13 patients received prophylactic bridging (PB) while the other 13 received therapeutic bridging (TB). The flap survival rate was 85.7% in the PB and 66.7% in TB (p = 0.39). Overall postoperative complications were slightly greater in the therapeutic anticoagulation cohort, however, with no significant preference for a complication type.
Conclusion Therapeutic bridging of high-risk patients with hypercoagulopathies or vascular diseases increases the overall surgical sites complications. When a clear systemic benefit of therapeutic anticoagulation is not present, a surgery related benefit is highly questionable.
Numerical simulation of a mechanical flocculation process with multi-chambers in series
Authors: Zong Jie , Yuan Fang , Zhan Minshu , Xu Wei , Cheng Guojian , Yu Aibing 
Published: March 2023

Abstract
A mechanical flocculation system with multi-chambers in series is commonly used as the advanced phosphorus removal technology for wastewater treatment. This work aims to numerically investigate the inner states and overall performance of industrial-scale mechanical flocculators in series. This is based on our previously developed computational fluid dynamics (CFD) flocculation model which is extended to consider the key chemical reactions of phosphorus removal. The effects of the number of flocculation chambers, locations, and sizes of the flocculation chamber connection as well as operational combinations of impeller speeds are investigated. With a decreasing number of flocculation chambers, the main vortexes and chemical reactions are weakened, while the small flocs form. Both the phosphorus removal efficiency η and the average floc size dp reduce as the number of flocculation chambers decreases. The connection location of flocculation chambers directly determines the turbulent flow, thus influencing the key performance indicators. However, the phosphorus removal efficiency η and average particle size dp are little affected by the size of the flocculation chamber connection. As the impeller speeds in series gradually increase, the gradient of floc size distribution in each chamber is enlarged and the chemical reaction is enhanced over the working volume.
In silico Mutagenesis and Modeling of Decoy Peptides Targeting CIB1 to
Obscure its Role in Triple-negative Breast Cancer Progression
Authors: Shahab Muhammad , Liang Chaoqun , Duan Xiuyuan , Zheng Guojun , Wadood Abdul 
Published: March 2023

Background::
Cancer is recognized globally as the second-most dominating and leading cause of morbidities. Breast cancer is the most often diagnosed disease in women and one of the leading causes of cancer mortality. In women, 287,850, and in males, 2710 cases were reported in 2022. Approximately 10–20% of all new cases of breast cancer diagnosed in the United States in 2017 were triple-negative breast cancers (TNBCs), which lack the expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2).

Objective::
This study aims to adopt different strategies for targeting calcium integrin-binding protein 1 by computer-aided drug design methods. Our results showed that the top four selected peptides interact with CIB1 more strongly than the reference peptide and restore normal cell function by engaging CIB1. Our binding affinity analyses explore an innovative approach to planning a new peptide to inhibit triple-negative breast cancer.

Methods::
Molecular dynamic simulation of the CIB1-UNC10245092 interaction highlights the potential peptide inhibitors through In-silico mutagenesis and designs novel peptide inhibitors from the reference peptide (UNC10245092) through residue scan methodology.

Results::
The top four designed peptides (based on binding free energy) were subjected to molecular dynamics simulations using AMBER to evaluate stability.

Conclusion::
Our results indicate that among the top five selected peptides, the mutant 2nd mutants have more potential to inhibit CIB1 than the reference peptide (UNC10245092) and have the potency to prevent or restore the tumor suppressor function of UNC10245092.
Evaluation of Immunity-related GTPase Family M Protein (IRGM) SNPs
among Egyptian Lupus Patients: A Case-control Study
Authors: Ali Ahmed Y. , Medhat Basma M. , Ashour Sara S. , Badr Amul M. , Dorgham Dalia , Ramadan Hala , Behiry Mervat E. 
Published: March 2023

Objective:
One of the potential factors that cause systemic lupus erythematosus (SLE) development is autophagy. Immunity-related GTPase family M protein (IRGM) has been shown to be linked to immune-mediated diseases. The aim of the current study was to assess the role of the IRGM-autophagy gene in SLE susceptibility in an Egyptian population and its relation to lupus nephritis.

Methods:
A case-control study was conducted in which a total of 200 subjects (100SLE and 100
healthy controls) were enrolled. Two single-nucleotide polymorphisms (SNPs) (rs10065172 and
rs4958847) were genotyped. Genotypes and alleles analysis was conducted to compare between
cases and controls, as well as a stratification analysis was conducted on the presence or absence of
lupus nephritis.

Results:
Among selected SNPs of IRGM, no association was found between both SNPs and SLE susceptibility. For rs10065172, the major expressed genotype was CC (61% and 71%) (Adj OR= 2.9, 95%= 0.545-15.5), followed by TC (34% and 27%) (Adj OR= 1.985, 95% = 0.357-11.041) in cases and controls, respectively. For rs4958847, AA and AG were comparably expressed in case [(43% and 39%) (Adj OR= 1.073, 95% = 0.483-2.382)] and control [(41% and 43%) (Adj OR= 1.24, 95% = 0.557- 2.763)], respectively. Additionally, no relationship among both SNPs and gen-der, lupus nephritis, disease activity, or disease duration, was observed

Conclusion:
IRGM SNPs (rs10065172 and rs4958847) expression was comparable among SLE patients and controls of the Egyptian cohort. Genotype and allele frequency of IRGM SNPs did not differ in lupus nephritis and non-lupus nephritis patients
Exploring the Acceptability of Text Messages to Inform and Support Shared Decision-making for Colorectal Cancer Screening: Online Panel Survey
Authors: Hwang Soohyun , Lazard Allison J , Reffner Collins Meredith K , Brenner Alison T , Heiling Hillary M , Deal Allison M , Crockett Seth D , Reuland Daniel S , Elston Lafata Jennifer 
Published: March 2023

Background
While online portals may be helpful to engage patients in shared decision-making at the time of cancer screening, because of known disparities in patient portal use, sole reliance on portals to support cancer screening decision-making could exacerbate well-known disparities in this health care area. Innovative approaches are needed to engage patients in health care decision-making and to support equitable shared decision-making.

Objective
We assessed the acceptability of text messages to engage sociodemographically diverse individuals in colorectal cancer (CRC) screening decisions and support shared decision-making in practice.

Methods
We developed a brief text message program offering educational information consisting of components of shared decision-making regarding CRC screening (eg, for whom screening is recommended, screening test options, and pros/cons of options). The program and postprogram survey were offered to members of an online panel. The outcome of interest was program acceptability measured by observed program engagement, participant-reported acceptability, and willingness to use similar programs (behavioral intent). We evaluated acceptability among historically marginalized categories of people defined by income, literacy, and race.

Results
Of the 289 participants, 115 reported having a low income, 146 were Black/African American, and 102 had less than extreme confidence in their health literacy. With one exception, we found equal or greater acceptability, regardless of measure, within each of the marginalized categories of people compared to their counterparts. The exception was that participants reporting an income below US $50,000 were less likely to engage with sufficient content of the program to learn that there was a choice among different CRC screening tests (difference –10.4%, 95% CI –20.1 to –0.8). Of note, Black/African American participants reported being more likely to sign up to receive text messages from their doctor’s office compared to white participants (difference 18.7%, 95% CI 7.0-30.3).

Conclusions
Study findings demonstrate general acceptance of text messages to inform and support CRC screening shared decision-making.
A SNOMED CT Mapping Guideline for the Local Terms Used to Document Clinical Findings and Procedures in Electronic Medical Records in South Korea: Methodological Study
Authors: Sung Sumi , Park Hyeoun-Ae , Jung Hyesil , Kang Hannah 
Published: March 2023

Background
South Korea joined SNOMED International as the 39th member country. To ensure semantic interoperability, South Korea introduced SNOMED CT (Systemized Nomenclature of Medicine–Clinical Terms) in 2020. However, there is no methodology to map local Korean terms to SNOMED CT. Instead, this is performed sporadically and independently at each local medical institution. The quality of the mapping, therefore, cannot be guaranteed.

Objective
This study aimed to develop and introduce a guideline to map local Korean terms to the SNOMED CT used to document clinical findings and procedures in electronic health records at health care institutions in South Korea.

Methods
The guidelines were developed from December 2020 to December 2022. An extensive literature review was conducted. The overall structures and contents of the guidelines with diverse use cases were developed by referencing the existing SNOMED CT mapping guidelines, previous studies related to SNOMED CT mapping, and the experiences of the committee members. The developed guidelines were validated by a guideline review panel.

Results
The SNOMED CT mapping guidelines developed in this study recommended the following 9 steps: define the purpose and scope of the map, extract terms, preprocess source terms, preprocess source terms using clinical context, select a search term, use search strategies to find SNOMED CT concepts using a browser, classify mapping correlations, validate the map, and build the final map format.

Conclusions
The guidelines developed in this study can support the standardized mapping of local Korean terms into SNOMED CT. Mapping specialists can use this guideline to improve the mapping quality performed at individual local medical institutions.
Orang-utans’ (<i>Pongo pygmaeus wurmbii</i>) Activity Pattern in Camp Release and Feeding Site of Lamandau Wildlife Sanctuary, Central Borneo, Indonesia
Authors: Amalia Novita , Perwitasari-Farajallah Dyah , Utami-Atmoko Sri Suci , Purbatrapsila Azhari 
Published: March 2023

The Bornean orang-utan (Pongo pygmaeus wurmbii) release process at Lamandau Wildlife Reserve applies the soft-release method. In this method, there is still provisioning additional food on the feeding site by human. The existence of camp release and feeding sites in the vicinity of release forests is assumed to have an impact on orang-utans’ activity patterns. This assumption is related to the principle of releasing them into their natural forest habitat, namely by reducing direct interaction between humans and orang-utans. The aims of this research were: (i) to measure the intensities of orang-utan presence on camp and feeding site, (ii) to analyze the correlation between phenology and orang-utan’s presence on camp and feeding site, and (iii) to assess orang-utan’s activity budgets, diet composition, and vertical used on camp, feeding site, and forest. Activity budgets of five group orang-utans with different categories based on age and sex were compared using the focal animal sampling method and instantaneous records. The analysis showed no correlation between the intensities of orang-utan presence and phenology. However, there were significant differences in activity patterns between adult and adolescent orang-utans. The findings revealed that adult orang-utans activity pattern tended to be high in resting at all observation locations while adolescents spending more their activity for feeding. Orang-utans at 0-10 m of height classes tend to do more activity. Almost all orang-utans feed on a non-forest diet (45-67%) in the camp release, feeding site, and surrounding. We assumed that the existence of a camp release and feeding site near the release point are affecting factors in a successful reintroduction of ex-rehabilitate orang-utans.
<i>Attacus atlas</i> (L.) sericin extract as an effective UV Protectant of <i>Bacillus thuringiensis</i> serotype <i>kurstaki</i> for controlling <i>Spodoptera litura</i> (Fab.)
Authors: Ningtyas Nindita Sabila , Rahmatullah Rahmatullah , Wiranto Aryo Seto Pandu , Sa’adah Nadya Sofia Siti , Alwandri Hipny , Asma’ Asma’ , Salsabila Tiara Purti , Adi Hanindyo , Sukirno Sukirno 
Published: March 2023

Bacillus thuringiensis serotype kurstaki is an entomopathogenic bacteria commonly used to control the cutworm Spodoptera litura (Fab.). However, B. thuringiensis has disadvantage of being easily degraded due to exposed sunlight. The objective of this research was to determine the effectiveness of adding A. atlas (L.) cocoon extract as UV protectant B. thuringiensis to the mortality of S. litura. This research formulated 2.5% of the original substance of A. atlas cocoon extract and B. thuringiensis serotype kurstaki strain HD-7 applied from commercial product DiPel-WP®. The formulation was exposed to sunlight for 0, 1, 2, and 3 weeks. The suspension treated for 20 individuals of first instar larvae S. litura shifted into the artificial diet using 3-5 replicates. The scanning electron microscope (SEM) method began from a sample that was vacuumed, sample coated, and observed on SEM with the electron in a certain level probe. This research showed that the mortality of S. litura decreased with the growth of S. litura. The mortality of S. litura achieved 20%-100% mortality after treatments. The A. atlas cocoon extract was effective as UV protectant B. thuringiensis for three weeks of exposure to sunlight. The SEM analysis represented that formulation of B. thuringiensis and A. atlas cocoon extract sunlight exposure for one week has harsher surface than exposed during three weeks.
Aspects of the Preparation of Elements that Make Transitions from the Low Bar to the Upper Bar
Authors: Neagu Gheorghe 
Published: March 2023

The paper deals with the issue of preparation and presentation of the elements that make transitions by dismounting from the low bar to the upper bar regarding the increase of diversity and continuity of integral uneven bar exercises. In this idea, I present new technical methods of performing this action through hitting on the thighs on the back in two technical variants. Elements with facial and dorsal run-up departure the two technical methods of transition to the upper bar can be easily adapted as bar climbs. These new technical actions to perform the dismount bring notes of originality and diversity in the new mobility and biomechanical expression of the possibilities of the human body, in interaction with the apparatus, in a unique technical way for performance artistic gymnastics. Collaterally, I present the possibility of taking over the two technical variants by the boys with the adaptation of these elements to parallel bars. From the methodical analysis of learning back fly dismounts, I present the formation of a new group of descents through hecht with back fly. From the dynamics of the development of the back fly I present new technical modes of presentation and combinations in the direct connection, after the upper bar is gripped. I also present a new technical way to present hecht with a 180 turn, after gripping the top bar.
PSIKOEDUKASI LITERASI KESEHATAN MENTAL PONDOK PESANTREN AL’ATSAR QURANIC CATURHARJO, PANDAK, BANTUL. DI.YOGYAKARTA
Authors: Yuniasih Dewi , Widiana Herlina Siwi , Iriyanti Annisa Furqon , Amirullah Abdul Karim , Suhendra Suhendra 
Published: March 2023

Rendahnya literasi kesehatan mental dapat menyebabkan rendahnya kemampuan mengenali problem kesehatan mental, timbulnya keyakinan dan sikap yang tidak tepat terhadap problem kesehatan mental, serta kurang tepatnya perilaku dalam mencari bantuan yang dibutuhkan. Pengabdian dengan tema psikoedukasi literasi kesehatan mental bagi para santri mempunyai tujuan agar para santri memiliki kemampuan mengenali problem kesehatan mental, memiliki keyakinan dan sikap yang tepat terkait problem kesehatan mental, dan mengubah pola saat mencari bantuan untuk problem kesehatan mental. Metode yang digunakan di Pondok pesantren Al’atsar Quranic Caturharjo, Pandak, Bantul. DI.Yogyakarta terdiri atas pretest, presentasi/ceramah tentang kesehatan mental, diskusi dan konsultasi psikologis para santri, dan diakhiri postest. Hasil rata-rata pretest sebesar 10,885, sedangkan rata-rata posttest menunjukkan skor sebesar 14,395. Hal ini menunjukkan kegiatan psikoedukasi yang bertujuan untuk meningkatkan literasi kesehatan mental pada santri tercapai, dilihat dari kenaikan angka postest dibandingkan dengan nilai pretest.