bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Synopsis of Ball Milling Organic Synthesis in the Last 25 Years
Authors: Margetić Davor 
Published: April 2023

Abstract:
Important progress in the transfer of organic reactions from solution conditions to automated
solid-state synthesis was published a quarter of a century ago. Since then, ball-milling organic
reactions have been slowly accepted by the chemical community as an additional synthetic
tool, and the area of its application is rapidly expanding. These developments in mechanochemical
synthesis are illustrated with selected literature examples.
Integrated 16S rRNA Sequencing and Untargeted Metabolomics Analysis to Reveal
the Protective Mechanisms of Polygonatum sibiricum Polysaccharide on Type 2 Diabetes
Mellitus Model Rats
Authors: Zhang Hui , Li Hanzhou , Pan Baochao , Zhang Shufang , Su Xiuhai , Sun Wenjuan , Zhang Tianyu , Zhang Zhaiyi , Lv Shuquan , Cui Huantian 
Published: April 2023

Background:
Polygonatum sibiricum polysaccharide (PSP) can improve insulin resistance and inhibit
oxidative stress. However, the detailed anti-diabetic mechanism of PSP is still poorly defined.

Methods:
In this study, the anti-diabetic, anti-inflammatory and anti-oxidative effects of PSP were evaluated on a
type 2 diabetes mellitus (T2DM) rat model. Furthermore, we investigated the changes in gut microbiota and serum
metabolites in T2DM rats after PSP treatment through 16S rRNA sequencing and untargeted metabolomics analyses.

Results:
Our results showed that PSP exhibited significant anti-diabetic, anti-inflammatory and anti-oxidative effects
on T2DM model rats. In addition, 16S rRNA sequencing showed that PSP treatment decreased the Firmicutes/
Bacteroidetes ratio in the gut. At the genus level, PSP treatment increased the relative abundances of Blautia,
Adlercreutzia, Akkermansia and Parabacteroides while decreasing Prevotella, Megamonas funiformis and Escherichia.
Untargeted metabolomics analysis revealed that PSP treatment could affect 20 metabolites, including hexanoylglycine,
(±)5(6)-DiHET, ecgonine, L-cysteine-S-sulfate, epitestosterone, (±)12(13)-DiHOME, glutathione, L-ornithine, Dmannose
6-phosphate, L-fucose, L-tryptophan, L-kynurenine, serotonin, melatonin, 3-hydroxyanthranilic acid, xylitol,
UDP-D-glucuronate, hydroxyproline, 4-guanidinobutyric acid, D-proline in T2DM model rats, these metabolites are
associated with arginine and proline metabolism, tryptophan metabolism, amino sugar and nucleotide sugar metabolism,
pentose and glucuronate interconversions, glutathione metabolism, arginine biosynthesis, ascorbate and aldarate
metabolism pathways. Spearman correlation analysis results showed that the modulatory effects of PSP on the arginine
and proline metabolism, tryptophan metabolism, and glutathione metabolism pathways were related to the regulation
of Prevotella, Megamonas funiformis, Escherichia, Blautia and Adlercreutzia.

Conclusion:
Our research revealed the therapeutic, anti-inflammatory and anti-oxidative effects of PSP on T2DM.
The mechanisms of PSP on T2DM are associated with improving the dysbiosis of gut microbiota and regulating
arginine and proline metabolism, tryptophan metabolism, and glutathione metabolism in serum.
Electrospinning of Nanofibers Incorporated with Essential Oils:
Applications in Food
Authors: Hossaeini Marashi Sayed Mahdi , Noori Seyed Mohammad Reza , Hashemi Mohammad , Raeisi Mojtaba , Noori Seyyed Mohammad Ali 
Published: April 2023

Abstract:
Nowadays, modern food preservation techniques have emerged in the last decade. Recently,
a combination of nanotechnology and active packaging has allowed the incorporation of
bioactive compounds, such as essential oils, into nanoscale electrospun fibers. This phenomenon
provides a new horizon in food safety and preservation. The incorporation of essential oils into
electrospun nanofibers can extend the duration of antimicrobial and antioxidant activity of essential
oils, which subsequently leads to longer shelf life, better preservation, and superior quality of
food. In the current paper, the essential oils incorporated into nanofibers have been reviewed. The
fabrication of nanofibers is usually carried out using different substances by applying various
manufacturing methods, including needleless and needle-based electrospinning techniques. In this
study, an emphasis on the antioxidant and antibacterial effects of electrospun nanofibers loaded
with essential oils and their application in food models has been laid. Nevertheless, other challenges
associated with using nanofibers incorporated with essential oils, such as their impact on
organoleptic properties, cytotoxicity, and durability, have been discussed to achieve a holistic view
of applying the electrospinning techniques in the food industry.
Intramolecular Click Cycloaddition Reactions: Synthesis of 1,2,3-Triazoles
Authors: Tashrifi Zahra , Khanaposhtani Mohammad Mohammadi , Bahadorikhalili Saeed , Larijani Bagher , Mahdavi Mohammad 
Published: April 2023

Abstract:
Click Chemistry, as a powerful tool, has been used for the synthesis of a variety of
1,2,3-triazoles. Among click cycloaddition reactions, intramolecular click reactions carried out in
azido-alkyne precursors has not been thoroughly reviewed. Hence, in this review, we have summarized
and categorised the recent literature (from 2012 on) based on the azidoalkynyl precursor's
type and a brief and concise description of the involved mechanisms is presented. Accordingly, we
have classified the relevant literature into three categories: (1) substitution precursors (2) addition
and (3) multi-component reaction (MCR) products.
Pediatric Trauma - A Silent Epidemic
Authors: Thakur Neha , Rai Narendra , Misra Samir , Misra Maitreyi 
Published: April 2023

Abstract:
Trauma is the leading cause of preventable deaths in children all over the world. In the majority of cases, children are innocent victims of road traffic accidents. They suffer from both short-term and long-term impacts of trauma. Deaths from road traffic accidents can be prevented by adopting simple road safety measures and the use of protective equipment. Worldwide programs have been initiated to curb this ever-rising menace; however, the success of these programs depends on their outreach and acceptance among the population in general. Golden hours in trauma management is the initial hour post-trauma, the success of resuscitation depends on the appropriate management of pediatric trauma victims in hospitals dedicated to the management of pediatric trauma victims. The current review highlights the epidemiology, pattern of injury, road safety measures, and global health initiatives for the prevention of accident-related injury in children. The shortcomings of this review are as follows- Firstly pediatric trauma is an exhaustive topic, it is impossible to cover all aspects of pediatric trauma. Thus, the review might have missed some important aspects of pediatric trauma. Secondly, the concept of a pediatric trauma registry is nonexistent in almost all developing countries; hence a true picture of pediatric trauma epidemiology and injury patterns is missing. Thirdly not much work has been done on pediatric trauma in developing countries leading to insufficient data from these countries.
General Practices’ Experiences With Patients’ Web-Based Access to Medical Records: Survey Study
Authors: Keuper Jelle , Batenburg Ronald , van Tuyl Lilian , Verheij Robert 
Published: April 2023

Background
Patients’ web-based access to their medical records is expected to promote their role and responsibility in managing their own health and treatments and supporting shared decision-making. As of July 2020, general practices in the Netherlands are legally obliged to provide their patients access to their electronic medical records. Web-based access provision is facilitated and stimulated through a national support program named OPEN.

Objective
We aimed to investigate general practice staff experiences with providing web-based access; investigate its impact on patient consultations, administrative actions, and patient inquiries; and investigate how it affects routine general practice workflow processes.

Methods
In October 2021, a total of 3813 general practices in the Netherlands were invited to complete a web-based survey that included questions regarding their experiences with the provision of web-based access to medical records and how it affects routine general practice workflow. Responses of general practices that started providing web-based access before 2020, in 2020, or in 2021 were analyzed to identify trends.

Results
Of 3813 invited general practices, 523 (13.72%) completed the survey. Approximately all responding general practices (487/523, 93.1%) indicated that they provide web-based access. Experiences with patients’ web-based access were diverse, with 36.9% (178/482) primarily positive, 8.1% (39/482) primarily negative, 42.3% (204/482) neutral, and 12.7% (61/482) could not (yet) indicate how they experienced web-based access. Of the total, two-thirds (311/473, 65.8%) reported an increase in e-consultations and a similar percentage (302/474, 63.7%) indicated an increase in administrative actions associated with web-based access provision. A small proportion of the practices (≤10%) experienced a decrease in patient contacts. Earlier adoption of web-based access was associated with a more positive attitude toward web-based access and more positive experienced effects related to patient contacts and general practice workflow.

Conclusions
The surveyed general practices mainly experienced providing web-based access as either neutral or mostly positive, despite an increased number of patient contacts and administrative burden that were associated with its adoption. Periodic monitoring of experiences is needed to understand the temporal or structural nature of both the intended and unintended effects of patients’ web-based access to medical records for general practices and their staff.
Kajian Penerapan Setandard Oprating Procedure di Kitchen Bali Hai Cruice Benoa
Authors: Putra Dewa Putu Septiana , Ismail Deden , Pambudi Bondan 
Published: April 2023

Penelitian ini adalah penelitian yang bertujuan untuk mengetahui kesesuaian antara Standard Operational Procedure yang berlaku dengan penerapan.Standard Operating Procedure merupakan pedoman tertulis yang berisi serangkaian prosedur kerja operasional Suatu organisasi agar berjalan efektif, serta mencapai sasaran atau target yang telah ditetapkan.Penelitian ini berlokasi di Bali Hai Cruise Benoa. Pada Standard Operating Procedure di Kitchen Bali Hai Cruise Benoa penyimpanan bahan makanan berpengaruh terhadap pengolahan bahan makanan, kualitas makanan dan penyajian bahan makanan tersebut.Oleh karena itu, penelitian ini bertujuan untuk mengetahui “bagaimana kajian penerapan Standard Operating Procedure(SOP) di kitchen Bali Hai Cruise Benoa”. Penelitian ini menggunakan data kuantitatif dan kualitatif, data diperoleh melalui penyebaran kuesioner dan doumentasi kepada karyawan atau staff kitchen Bali Hai Cruise Benoa.Analisis yang digunakan dalam penelitian ini yaitu Analisis Binomial. Hasil penelitian ini menyatakan bahwa secara keseluruhan penerapan Standard Operating Procedure (SOP) di kitchen Bali Hai Cruise Benoa telah memenuhi standard dan persyaratan yang berlaku.

This research is research that aims to determine the compatibility between the applicable Standard Operating Procedures and implementation. Standard Operating Procedures are written guidelines that contain a series of operational work procedures for an organization to run effectively, and achieve the goals or targets that have been set. This research is located in Bali Hi Cruise Benoa. In the Standard Operating Procedure at Kitchen Bali Hai Cruise Benoa food storage affects the processing of food ingredients, food quality and presentation of the food ingredients. in the Bali Hi Cruise Benoa kitchen.” This study uses quantitative and qualitative data, data obtained through the distribution of questionnaires and documentation to employees or staff of the Bali Hai Cruise Benoa kitchen. The analysis used in this study is binomial analysis. The results of this study state that overall the implementation of the Standard Operating Procedure (SOP) in the Bali Hai Cruise Benoa kitchen has met the applicable standards and requirements.
Pengaruh Pelatihan dan Kepemimpinan Terhadap Produktivitas Kerja Karyawan di Noaa Social Dining Seminyak Kuta
Authors: Dewi I Gusti Agung Ayu Intan Sinta , Ismail Deden , Dewi I Gusti Ayu Melistyari 
Published: April 2023

Pelatihan dan Kepemimpinan sangat penting untuk produktivitas kerja. Tujuan penelitian ini untuk mengetahui pengaruh pelatihan dan kepemimpinan terhadap produktivitas kerja karyawan. Penelitian dilakukan pada bulan oktober hingga bulan April 2021. Populasi dalam penelitian ini adalah seluruh Staff Noaa Social dining Seminyak Kuta dengan sampel 30 orang dengan Teknik sampling jenuh. Teknik analisis data yaitu regresi linier berganda. Permasalahan yang akan diteliti adalah; (1) bagaimanakah pengaruh pelatihan terhadap produktivitas kerja karyawan di Noaa Social dining Seminyak? (2) Bagaimanakah pengaruh kepemimpinan terhadap produktivitas kerja karyawan di Noaa Social dining Seminyak Kuta? Dan (3) bagaimanakan pengaruh pelatihan dan kepemimpinan terhadap produktivitas kerja karyawan di Noaa Social dining Seminyak Kuta? Hasil penelitian menunjukkan bahwa Kepemimpinan (X2) berpengaruh signifikan secara parsial terhadap Produktivitas dengan Y. Adapun dimensi kepemimpinan yang berpengaruh adalah Katalisator dan Bersikap Menghargai dan dimensi yang tidak berpengaruh adalah Bersifat adil, Memberi sugesti, Mendukung tujuan, Menciptakan rasa aman, Sebagai wakil organisasi dan Sumber inspirasi.

Training and Leadership is very important for work productivity. The purpose of this study was to determine the effect of training and leadership on employee productivity. The research was conducted from October to April 2021. The population in this study were all Noaa Social dining Seminyak Kuta staff with a sample of 30 people using a saturated sampling technique. The data analysis technique is multiple linear regression. The problems to be studied are; (1) what is the effect of training on employee work productivity at Noaa Social dining Seminyak? (2) How does leadership affect employee work productivity at Noaa Social dining Seminyak Kuta? And (3) what is the effect of training and leadership on employee work productivity at Noaa Social dining Seminyak Kuta? The results of the study show that Leadership (X2) has a partially significant effect on Productivity with Y. The influential dimensions of leadership are Catalyst and Appreciative and dimensions that are not influential are Fair, Giving suggestions, Supporting goals, Creating a sense of security, As an organizational representative and a source of inspiration.
TAKK som specialpedagogiskt didaktiskt verktyg i förskolans undervisning
Authors: Palla Linda 
Published: April 2023

Syftet är öka kunskapen om hur yrkesverksamma i förskolan säger sig använda TAKK, tecken som alternativ kompletterande kommunikation, i förskolans undervisning. Vidare syftar studien till att belysa hur TAKK kan förstås i ljuset av specialpedagogisk didaktik. Didaktiska frågor har väglett analysen: Var och när uttrycker yrkesverksamma i förskolan att TAKK används? För och med vem/vilka uttrycker yrkesverksamma i förskolan att TAKK kan användas? Hur och varför uttrycker yrkesverksamma i förskolan att TAKK kan användas? Studien har avgränsats till att omfatta 30 yrkesverksammas utsagor i ett inlägg i internetforumet Facebooks grupp ”Förskolan.se”. Vald metod är netnografi och analysen är kvalitativ med specialpedagogisk didaktisk modellering som teoretiskt angreppssätt. Resultatet visar att beskrivningar av användandet av TAKK kan liknas vid ett flerstämmigt förhållningssätt då TAKK beskrivs användas i undervisning på flera olika vis, i flera olika situationer och i flera olika miljöer – med alla och för alla. Slutsatsen dras att med specialpedagogisk didaktisk modellering kan TAKK bli ett verktyg brett nog att utgöra stöd på inkluderande vis.
ENGLISH ABSTRACT
SAAC as a special education didactic tool in preschool educationThe purpose is to increase knowledge about how SAAC, signing as augmentative and alternative communication, is said to be used by professionals in preschool education. Furthermore, the study aims to shed light on how SAAC can be understood in the light of special education didactics. Didactic questions have guided the analysis: Where and when is SAAC said to be used? Who is/are SAAC said to be used with and for? How and why is SAAC said to be used? The study has been limited to the statements of 30 professionals in a post in the internet forum Facebook’s group “Förskolan.se”. The chosen method is netnography and the analysis is qualitative with special education didactic modelling as theoretical approach. The results show that descriptions of the use of SAAC can be likened to a multi-voiced approach as SAAC is described as being used in the education in several different ways, in several different situations and in several different environments – with everyone and for everyone. The conclusion is drawn that with special education didactic modeling, SAAC can become a tool broad enough to constitute support in an inclusive way.
Groundwater Potential Zone Classification Using Geospatial Approach
Authors: Hardanto Afik , Mustofa Asna , Ardiansyah Ardiansyah 
Published: April 2023

Groundwater is an important process in the watershed hydrological system. Serayu watershed, the largest in Central Java Province, has bio-physic spatial variability that influences groundwater recharging. The aim is to derive the groundwater potential zone of the Serayu watershed. Five thematic maps used and applied for groundwater potential analysis, were lithology, land use land cover, lineament density, drainage density, and slope gradient. Distribution of Lithology data, Digital Elevation Model (DEM), and Landsat 8 image were analyzed to thematic raster with 1 x 1 km resolution. Weighted index was calculated regarding the relation of five influence parameters then were overlaid and calculated by using QGIS-calculator. Groundwater classified into five categories, namely poor, low, moderate, good, and very good. Based on the final groundwater potential map, 0.02% of 3,727 km2 is poor category, however most of Serayu watershed have moderate to good (48.77 and 29.77 %, respectively). The percentage of very good (10.57%) and low (10.87%) classes were rather similar. Spatial variability of groundwater distribution indicates the complex characteristics of the Serayu watershed, so more serious attention from the perspective of research and management of water resources in the future, is needed. Keywords: Groundwater, Multi-criteria, QGIS, Recharging, Serayu watershed.
Effect of Packaging Material Types on Antioxidant Activity, Fat Content, and Ash Content in the Imported and Local Yellow Soybean Tempeh
Authors: Puspasari Diah Ayu , Utama Zaki , Ningrum Andriati 
Published: April 2023

Tempeh known as indigenous food that has high nutrients and antioxidant compounds. Tempeh was produced from the fermentation of soybean with Rhizopus sp. Tempeh usually was wrapped with plastic or banana leaf. The purpose of this study to know the effect of soybean originated (import and local soybean) and the packaging material types (plastic, teakwood leaf, hibiscus leaf, and banana leaf) on antioxidant activity, fat content, and ash content of tempeh. The methods of this research were antioxidant activity analyses with DPPH (1,1-diphenyl-2- picrylhydrazil) Radical Scavenging Activity method, fat analyses with soxhlet method, ash analyses with dry method. The results of this research showed that the tempeh from local soybeans with waru leaf packaging had the highest antioxidant activity (53,43%), tempeh from import soybeans with plastic packaging had the highest fat content (48,89%), and tempeh from import soybeans with waru leaf packaging had the highest ash content (2,19%). We found that the soybean origin (import and local soybean) and the packaging types (plastic, waru leaf, jati leaf, and banana leaf) had significant effect (p<0,05) on antioxidant activity, fat content, and ash content of tempeh. Keywords: Antioxidant activity, Ash content, Fat content, Soybean, Tempeh.
Effect of Magnetic Field on the Flame Characteristics of Droplet Combustion of Coconut and Palm Oil
Authors: Perdana Dony , Asrori Asrori , Hanifudin Muhamad , Dinata Novembrian Isam 
Published: April 2023

Experimental has been conducted on the effects of variations in the direction of the magnetic fields on flames characteristic of droplets combustion of coconut and palm oils. Two variations of the directions magnetic field N-N and S-N were used in this experiment by placing droplets of vegetable oils on the type K thermocouple between two permanent magnet rods. High-speed camera (120 frame per second) recorded the flames up to extinguished. The result showed that S-N magnetic fields affected on shorter burning time of coconut and palm oil, respectively 670 ms and 871 ms, with the highest temperature of 816.25 oC and 778 oC. The flame height produced by the S-N magnetic field in coconut oil is 34.36 mm shorter, ignitions delay time for all oils has faster than the N-N magnetic field. The strong magnetic field direction increases the oxygen concentrations and fuel molecules around the reaction zone, causing shorter combustion. This combustion produces different flame evolution, shape, height, temperature, and ignition delay times. Keywords: Flames evolution, Flames height, Flames temperature, Ignition delay, Vegetable oils.
Effectiveness of various language strategies for helping pet owners appreciate the value of preventive care
Authors: McKay Charlotte H. , Nichols Nicole , Lefebvre Sandra L. 
Published: April 2023

Abstract

OBJECTIVE
To identify more effective language strategies for helping pet owners appreciate the value and importance of preventive veterinary care and encouraging more regular visits.

SAMPLE
15 pet owners representing a mix of demographic and other characteristics.

PROCEDURES
This qualitative study began with a communication and research audit, followed by interviews with subject matter experts, development of language stimuli (messages about the importance of veterinary care and encouraging pet owners to prioritize wellness visits), three 2-hour online focus group sessions with study participants (4 to 6/group) to test and discuss the language stimuli, and 1-hour one-on-one interviews with 5 of these participants to measure emotional responses to optimized stimuli.

RESULTS
Language stimuli testing showed that simply telling pet owners how veterinary care is valuable does not work. What did work was focusing on the pet owner’s relationship with their pet, tying preventive care into the animal’s overall health and happiness, and emphasizing a veterinarian’s experience versus their qualifications. Personalized recommendations were perceived as most valuable to owners. Addressing cost head-on, demonstrating understanding, empowering pet owners to ask questions, and providing payment options were identified as strategies that could help owners see they can afford routine care now.

CLINICAL RELEVANCE
Results suggested that by focusing on experience, relationships, and personalized care, veterinarians can address pet owners’ concerns while promoting the importance of preventive care, including regular checkups. Additional research is needed to evaluate the impact of this language on pet owner perceptions, behaviors, and outcomes in clinical settings.