bluuebunny/crossref_metadata_2025_split huggingface dataset:
An Asset-based Community Development (ABCD) Approach to Integrating Natural Capital as Touristic Assets
Authors: Campo Catherine , De Guzman Rhea 
Published: January 2025

Touristic assets, whether natural, cultural, human, social, built, or political are the backbone of tourism development. They attract visitors and make the destination a unique one. Now, more than ever, the community is considered an exceptional touristic asset. They are the capital of community-based tourism (CBT), an alternative route to mass tourism development. Anchored with the path of a resource-focused approach called the Asset-based Community Development (ABCD) framework, this ethnographic study discovered the natural capital of select indigenous sitio in Panaytayan, Mansalay, Oriental Mindoro, Philippines. Connecting the dots between touristic assets, CBT, and ABCD, this study strengthens the significance of the bottom-up approach in tourism development- a growth perspective from the inside out. Mapping and observation were done to explore the unexplored beauty of the community through team fieldwork. The study reveals that the community has a wide array of flora and nature-based destinations that served as the community’s means of survival and shaped their livelihood. This study supports the importance of gauging the community’s assets to help them become self-sufficient. The result of this mapping urged the researchers to propose an eco-drive capability training program to protect their natural capital not solely for tourism but more for environmental sustainability, especially for younger generations. It is also recommended to strengthen the role of ABCD through inclusive community participation and asset mobilization. Forthcoming researchers may go beyond the natural capital by showcasing intangible assets like traditional crafts, storytelling, indigenous practices, and local cuisine to deliver experiential memories as potential tourism draws.
De Quervain’s disease - An Ayurvedic perspective
Authors: Das Dany V , Sreelekha M P Sreelekha , Aneesh S Aneesh 
Published: January 2025

De Quervain's disease is the condition of inflammation, thickening, and stenosis of the synovial sheath surrounding tendons of abductor pollicis longus and extensor pollicis brevis. It is commonly affecting women aged 30-50 years. Symptoms are pain and tenderness at radial styloid process, swelling, difficulty in thumb movements and"stop and go" sensation in the thumb. In ayurveda, the tendons can be co-related with snayu and symptoms in De quervains diseases including pain (shoola), stiffness (stambha), and limited movement (akshepana) in joints can be co related with symptoms of vata vyadhi. Snayugatha vatha is categorized under vata vyadhi. The vitiated vata dosha affecting the sharira snayu (tendons and ligaments) particularly in the angushta moola of manibandha sandhi (wrist joint) and causes Angusta moola parswa snayugatha vatha vyadhi. The treatment of snayugata vata are snehana (oleation therapy), upanaha (fomentation), and agnikarma (thermal therapy). These ayurvedic treatments offer a cost-effective and simple approach for managing De Quervain's disease.
Keywords : Snayugatha vata, Vata vyadhi, De- Quervain’s disease.
Analyse pragmatique des discours haineux dans le réseau social Facebook
Authors: BOUKRI Souhila , ARDJANI Sanaa 
Published: January 2025

Les discours haineux visent à attaquer, dégrader ou discriminer un individu ou un groupe en raison de leur appartenance à une catégorie sociale ou identitaire spécifique. Ce phénomène est récurrent sur les réseaux sociaux, y compris sur Facebook. Les commentaires haineux, les publications offensantes et les messages de stigmatisation sont courants sur la plateforme, malgré les politiques strictes de Facebook visant à limiter leur propagation. Cet article s'inscrit dans le domaine de la pragmatique qui prend en compte tous les phénomènes liés au langage dans leur contexte d'utilisation, nous nous intéressons à étudier le discours haineux sur le réseau social Facebook. Nous avons effectué des observations primaires sur cette plateforme (réseau que nous adoptons comme terrain d’investigation) elles nous ont permis de constater la présence de différentes manières de discours haineux dans les publications et les commentaires. L'analyse de notre corpus comporte des captures d'écran, des publications et des commentaires relatifs à différents événements. Il est question d’aborder les différentes étapes de l'analyse du corpus et de proposer une interprétation des résultats obtenus.
O Impacto da Enfermagem em Cuidados Paliativos
Authors: Capelario Elenice , Ramos Vivian de Brito Formiga 
Published: January 2025

RESUMO
Introdução: Os cuidados paliativos emergiram na década de 1960 com a fundação do primeiro hospício por Cicely Saunders na Inglaterra. Originalmente, esses cuidados eram definidos como um tratamento abrangente e intensivo para pacientes sem perspectivas de cura. Nos anos 90, a abordagem evoluiu para um cuidado ativo e integral voltado para a qualidade de vida dos pacientes em estado terminal. A definição foi ampliada nos anos 2000 para incluir suporte emocional, espiritual e psicológico aos pacientes e suas famílias, além do alívio da dor. Objetivo: Explorar o papel fundamental do enfermeiro na assistência a pacientes em cuidados paliativos. Metodologia: Realizou-se uma revisão bibliográfica qualitativa com propósitos descritivos. Resultados e Discussão: Identificou-se a necessidade de superar quatro principais barreiras ao acesso aos cuidados paliativos: a falta de capacitação e conhecimento dos profissionais de saúde, barreiras sociais e culturais relacionadas a crenças sobre dor e morte, e restrições regulatórias no uso de analgésicos e opioides. Estes desafios evidenciam a importância da formação contínua para estudantes e profissionais de enfermagem. O desenvolvimento dos cuidados paliativos no Brasil tem mostrado avanços significativos. Conclusão: É essencial que as instituições de ensino integrem disciplinas focadas em cuidados paliativos no currículo de enfermagem. Diversas abordagens podem ser aplicadas, mas o foco principal deve ser o alívio e conforto do paciente. Em situações graves, a analgesia contínua, frequentemente com opioides, deve ser uma prioridade, permitindo ao paciente a possibilidade de planejar sua trajetória final se assim desejar.
Palavras-chave: Enfermagem; Cuidados Paliativos; Assistência de Enfermagem.
PERANAN KONSELING DAN PELAYANAN PASTORAL BAGI PEMULIHAN LUKA BATIN ANAK AKIBAT KEKERASAN DALAM KELUARGA DI GEREJA HKBP JATIWARINGIN JAKARTA TIMUR
Authors: Halawa Operahmat 
Published: January 2025

Penelitian ini dilatar belakangi oleh adanya fenomena kekerasan anak yang terjadi dalam keluarga pastinya menimbulkan trauma atau luka batin, baik secara fisik, emosional, psikologi maupun kepribadian sosialnya. Luka batin ini akan semakin rumit karena kemungkinan akan berdampak lama atau sampai anak menjadi dewasa. Hal ini jika tidak segera dipulihkan dapat memicu perilaku agresif yang seringkali tidak terkontrol, menjadi budaya dalam hidupnya, dan diturunkan kepada generasi berikutnya. Karena itu, untuk menolong dan memulihkannya, diperlukan konseling dan pelayanan pastoral. Adapun yang menjadi metode penelitian yang digunakan oleh penulis dalam tesis ini adalah metode penelitian kualitatif deskriptif. Subyek penelitian ini adalah para Hamba Tuhan, Majelis Gereja, Evangelist, Guru Sekolah Minggu, Pendamping Anak dan Jemaat yang melayani di HKBP Jatiwaringin. Penggumpulan data menggunakan wawancara, observasi, dan dokumentasi. Dalam penelitian ini, penulis menemukan bahwa konseling dan pelayanan pastoral sangat berperan dalam pemulihan luka batin anak
PENGARUH MODEL PEMBELAJARAN JARAK JAUH DAN MEDIA PEMBELAJARAN ONLINE TERHADAP MINAT BELAJAR PENDIDIKAN AGAMA KRISTEN SISWA SMA DI KOTA BOGOR
Authors: Dewanto Yogi 
Published: January 2025

Penulisan ini mengemukakan rumusan masalah seberapa besar pengaruh model pembelajaran jarak jauh terhadap minat belajar PAK siswa, seberapa besar pengaruh penggunaan media pembelajaran online terhadap minat belajar PAK Siswa, seberapa besar pengaruh model pembelajaran jarak jauh dan juga penggunaan media pembelajaran online secara bersama-sama terhadap minat belajar PAK Siswa. Penelitian menggunakan pendekatan metode kuantitatif yang bersifat korelasional antar variabel dengan menggunakan Analisa statistik untuk mengetahui atau mengukur ada tidaknya pengaruh antara dua variable independen: Model Pembelajaran Jarak Jauh (X1), Media Pembelajaran Online (X2) dan satu variable dependent: Minat Belajar PAK Siswa (Y). Penelitian mengambil sebanyak 150 sampel sebagai data primer. Responden adalah siswa SMA Negeri kota Bogor meliputi enam kecamatan.Hasil Penelitian menunjukkan: Model Pembelajaran Jarak Jauh (X1) memiliki tingkat signifikansi sebesar 0,000 < 0,05. Hasil t hitung yang diperoleh adalah 5,892 > 1,9768 dari t table, sehingga H01 ditolak dan Ha1 diterima. Maka dapat disimpulkan bahwa X1 berpengaruh positif dan signifikan terhadap Y.
Features of the excise tax on the pharmaceutical ethanol: current issues
Authors: Sekushin Aleksei Yur'evich 
Published: January 2025

The subject of the study is the excise tax on the pharmaceutical substance of ethyl alcohol, various aspects, features in the implementation of the excise tax on the pharmaceutical substance of ethyl alcohol. The purpose of the study is to analyze the excise tax on the pharmaceutical substance of ethyl alcohol, identify problems based on the analysis of the excise tax on the pharmaceutical substance of ethyl alcohol, and propose directions for the development of the excise tax on the pharmaceutical substance of ethyl alcohol for the purposes of harmonization of legislation. The author examines in detail such features of the excise tax on the pharmaceutical substance of ethyl alcohol as: lists of pharmaceutical products, the object of taxation of excise tax, the application of various rates when performing operations with the pharmaceutical substance of ethyl alcohol, the specifics of the application of deductions for this excise tax, as well as other issues. This study was conducted based on the application of general scientific research methods, including systematic, logical, comparative analysis, and the method of analogy. The main conclusions of the study are that this tax is aimed at controlling the misuse of medical alcohol in the production of alcoholic beverages, imposing excise taxes on such production in order to equalize its value. As part of the implementation of the new mechanism, pharmaceutical companies face an additional administrative burden regarding the need to confirm the intended use of the pharmaceutical substance ethyl alcohol. At the same time, the author highlights an urgent problem for the excise tax on the pharmaceutical substance of ethyl alcohol, which is an additional tax burden in the case of the purchase of more than 500,000 thousand liters of pharmaceutical substance of ethyl alcohol for the production of medicines that are not included in the lists of pharmaceutical products. The scientific novelty lies in the refinement of a new approach to state regulation of excise taxation, based on a detailed analysis of legislative norms and rules, as well as an assessment of the effects of their impact on the pharmaceutical industry.
Bactericidal Properties of the Sol-gel Layer on Polymer Substrates in Medical Applications
Authors: Armatys Paulina , Długoń Elżbieta , Smółka Wojciech , Sobota Robert , Frączek-Szczypta Aneta , Markowski Jarosław , Stodolak-Zych Ewa 
Published: January 2025

Polymeric biomaterials are a group of plastics used in medical devices, implants, and artificial organ components. In order to maintain the higher asepticity of the products, solutions based on the modification of the volume or surface of a plastic with biocidal agents, e.g. antibiotics, nanoparticles, are used. One of the methods used to impart biocidal properties to the material can be the use of layers applied by the sol-gel method. The aim of this study was to produce homogeneous and durable coatings on inert and hydrophobic silicone surfaces based on polysiloxane sols with biocidal activity against model bacteria: Gram negative (Escherichia coli, Klebsiella pneumoniae) and Gram positive (Staphylococcus aureus, Enterococcus faecalis). This paper presents results of investigations on a commercial biomedical silicone material (DEMED Sp. zoo) modified with eight sols; siloxane (TD), phenol-siloxane (FD), siloxane-aluminum (TD-Al), siloxane-titanium (TD-Ti), titanium (Ti), zinc (Zn), and TD and TD-Al sols modified with green tea extract (TD-GT, TD-Al-GT). The reference for the tested materials was unmodified silicone. In order to be prepared for coating, the siloxane samples were etched with hydrofluoric acid. Residual acid was removed from the silicone by washing and the substrates were then coated with sols by means of dip coating. The modified materials were then polymerized at 100°C for one week. The produced layered composites were subjected to microstructural, physicochemical, structural and microbiological analysis by contacting them with Gramm negative and Gramm positive bacteria. It was shown that the strongest biocidal properties were exhibited by samples modified with the sols based on - Zn, TD-Ti, Ti, TD-Al-GT and TD-GT.
Implications of the Network Theory for the Treatment of Mental Disorders
Authors: Schumacher Lea , Klein Jan Philipp , Elsaesser Moritz , Härter Martin , Hautzinger Martin , Schramm Elisabeth , Kriston Levente 
Published: August 2023

ImportanceConceptualizing mental disorders as latent entities has been challenged by the network theory of mental disorders, which states that psychological problems are constituted by a network of mutually interacting symptoms. While the implications of the network approach for planning and evaluating treatments have been intensively discussed, empirical support for the claims of the network theory regarding treatment effects is lacking.ObjectiveTo assess the extent to which specific hypotheses derived from the network theory regarding the (interindividual) changeability of symptom dynamics in response to treatment align with empirical data.Design, Setting, and ParticipantsThis secondary analysis entails data from a multisite randomized clinical trial, in which 254 patients with chronic depression reported on their depressive symptoms at every treatment session. Data collection was conducted between March 5, 2010, and October 14, 2013, and this analysis was conducted between November 1, 2021, and May 31, 2022.InterventionThirty-two sessions of either disorder-specific or nonspecific psychotherapy for chronic depression.Main Outcomes and MeasuresLongitudinal associations of depressive symptoms with each other and change of these associations through treatment estimated by a time-varying longitudinal network model.ResultsIn a sample of 254 participants (166 [65.4%] women; mean [SD] age, 44.9 [11.9] years), symptom interactions changed through treatment, and this change varied across treatments and individuals. The mean absolute (ie, valence-ignorant) strength of symptom interactions (logarithmic odds ratio scale) increased from 0.40 (95% CI, 0.36-0.44) to 0.60 (95% CI, 0.52-0.70) during nonspecific psychotherapy and to 0.56 (95% CI, 0.48-0.64) during disorder-specific psychotherapy. In contrast, the mean raw (ie, valence-sensitive) strength of symptom interactions decreased from 0.32 (95% CI, 0.28-0.36) to 0.26 (95% CI, 0.20-0.32) and to 0.09 (95% CI, 0.02-0.16), respectively. Changing symptom severity could be explained to a large extent by symptom interactions.Conclusions and RelevanceThese findings suggest that specific treatment-related hypotheses of the network theory align well with empirical data. Conceptualizing mental disorders as symptom networks and treatments as measures that aim to change these networks is expected to give further insights into the working mechanisms of mental health treatments, leading to the improvement of current and the development of new treatments.Trial RegistrationClinicalTrials.gov Identifier: NCT00970437
Addressing Global Environmental Challenges to Mental Health Using Population Neuroscience
Authors: Schumann Gunter , Andreassen Ole A. , Banaschewski Tobias , Calhoun Vince D. , Clinton Nicholas , Desrivieres Sylvane , Brandlistuen Ragnhild Eek , Feng Jianfeng , Hese Soeren , Hitchen Esther , Hoffmann Per , Jia Tianye , Jirsa Viktor , Marquand Andre F. , Nees Frauke , Nöthen Markus M. , Novarino Gaia , Polemiti Elli , Ralser Markus , Rapp Michael , Schepanski Kerstin , Schikowski Tamara , Slater Mel , Sommer Peter , Stahl Bernd Carsten , Thompson Paul M. , Twardziok Sven , van der Meer Dennis , Walter Henrik , Westlye Lars ,   environMENTAL Consortium, Heinz Andreas , Lett Tristram , Vaidya Nilakshi , Serin Emin , Neidhart Maja , Jentsch Marcel , Eils Roland , Taron Ulrike-Helene , Schütz Tatjana , Banks James Richard , Meyer-Lindenberg Andreas , Tost Heike , Holz Nathalie , Schwarz Emanuel , Stringaris Argyris , Christmann Nina , Jansone Karina , Siehl Sebastian , Ask Helga , Fernández-Cabello Sara , Kjelkenes Rikka , Tschorn Mira , Böttger Sarah Jane , Bernas Antoine , Marr Lena , Feixas Viapiana Guillem , Eiroa-Orosa Francisco José , Gallego Jaime , Pastor Alvaro , Forstner Andreas J. , Claus Isabelle , Miller Abigail , Heilmann-Heimbach Stefanie , Boye Mona , Wilbertz Johannes , Schmitt Karen , Petkoski Spase , Pitel Séverine , Otten Lisa , Athanasiadis Anastasios-Polykarpos , Pearmund Charlie , Spanlang Bernhard , Alvarez Elena , Sanchez Mavi , Giner Arantxa , Renner Paul , Gong Yanting , Dai Yuxiang , Xia Yunman , Chang Xiao , Liu Jingyu , Young Allan , Ogoh George 
Published: August 2023

ImportanceClimate change, pollution, urbanization, socioeconomic inequality, and psychosocial effects of the COVID-19 pandemic have caused massive changes in environmental conditions that affect brain health during the life span, both on a population level as well as on the level of the individual. How these environmental factors influence the brain, behavior, and mental illness is not well known.ObservationsA research strategy enabling population neuroscience to contribute to identify brain mechanisms underlying environment-related mental illness by leveraging innovative enrichment tools for data federation, geospatial observation, climate and pollution measures, digital health, and novel data integration techniques is described. This strategy can inform innovative treatments that target causal cognitive and molecular mechanisms of mental illness related to the environment. An example is presented of the environMENTAL Project that is leveraging federated cohort data of over 1.5 million European citizens and patients enriched with deep phenotyping data from large-scale behavioral neuroimaging cohorts to identify brain mechanisms related to environmental adversity underlying symptoms of depression, anxiety, stress, and substance misuse.Conclusions and RelevanceThis research will lead to the development of objective biomarkers and evidence-based interventions that will significantly improve outcomes of environment-related mental illness.
Plasma β‐synuclein, GFAP, and neurofilaments in patients with malignant gliomas undergoing surgical and adjuvant therapy
Authors: Abu‐Rumeileh Samir , Barba Lorenzo , Bache Matthias , Halbgebauer Steffen , Oeckl Patrick , Steinacker Petra , Güttler Antje , Keßler Jacqueline , Illert Jörg , Strauss Christian , Vordermark Dirk , Otto Markus 
Published: August 2023

AbstractWe analyzed the longitudinal concentrations and prognostic roles of plasma β‐synuclein (β‐syn), glial fibrillary acidic protein (GFAP), and neurofilament proteins (NfL and NfH) in 33 patients with malignant gliomas, who underwent surgical and adjuvant therapy. GFAP and NfL levels were increased in patients with glioblastoma compared to cases with other tumors. β‐syn, NfL and NfH increased after surgery, whereas GFAP decreased at long‐term follow‐up. β‐syn and neurofilament concentrations were influenced by surgery and/or radiotherapy regimens. GFAP and neurofilament levels were significantly associated with survival. Plasma neuronal and astrocytic biomarkers are differentially altered in malignant glioma types and displayed distinct trajectories after surgical and adjuvant therapy.
Design Rule Hidden from The Eye in S/N‐Bridged Ancillary Ligands for Copper(I) Complexes Applied to Light‐Emitting Electrochemical Cells
Authors: Giobbio Ginevra , Cavinato Luca M. , Fresta Elisa , Montrieul Anaïs , Umuhire Mahoro Gilbert , Lohier Jean‐François , Renaud Jean‐Luc , Linares Mathieu , Gaillard Sylvain , Costa Rubén D. 
Published: August 2023

AbstractEnhancing low‐energy emitting Cu(I)‐ionic transition metal complexes (iTMCs) light‐emitting electrochemical cells (LECs) is of utmost importance towards Cu(I)‐iTMC‐based white‐emitting LECs. Here, the ancillary ligand design includes (i) extension of π‐systems and (ii) insertion of S‐bridge between heteroaromatics rings. This led to two novel heteroleptic Cu(I)‐iTMCs: 2‐(pyridin‐2‐yl‐l2‐azanyl)quinoline (CuN2) and 2‐(naphthalen‐2‐ylthio)quinoline (CuS2) as N^N and bis[(2‐diphenylphosphino)phenyl] ether as P^P, exhibiting improved photoluminescence quantum yields (ϕ) and thermally activated delayed fluorescence processes compared to their reference Cu(I)‐iTMCs: di(pyridin‐2‐yl)‐l2‐azane (CuN1) and di(pyridin‐2‐yl)sulfane (CuS1). Despite CuS2 stands out with the highest ϕ (38% vs 17 / 14 / 1% for CuN1 / CuN2 / CuS1), only CuN2‐LECs show the expected enhanced performance (0.35 cd A−1 at luminance of 117 cd m−2) compared to CuN1‐LECs (0.02 cd A−1 at6 cd m−2), while CuS2‐LECs feature low performances (0.04 cd A−1 at 10 cd m−2). This suggests that conventional chemical design rules are not effective towards enhancing device performance. Herein, nonconventional multivariate statistical analysis and electrochemical impedance spectroscopy studies allow to rationalize the mismatch between chemical design and device performance bringing to light a hidden design rule: polarizability of the ancillary ligand is key for an efficient Cu(I)‐iTMC‐LECs. All‐in‐all, this study provides fresh insights for the design of Cu‐iTMCs fueling research on sustainable ion‐based lighting sources.
Origin and Energy of Intra‐Gap States in Sensitive Near‐Infrared Organic Photodiodes
Authors: Ma Xiao , Ollearo Riccardo , van Gorkom Bas T. , Weijtens Christ H. L. , Fattori Marco , Meskers Stefan C. J. , van Breemen Albert J. J. M. , Janssen René A. J. , Gelinck Gerwin H. 
Published: August 2023

AbstractTrap states in organic semiconductors are notoriously detrimental to the performance of organic electronics. However, the origin and energetics of trap states remain largely elusive and under debate, especially for bulk‐heterojunction (BHJ) photodiodes consisting of electron donor and acceptor materials. Combining three sensitive techniques now enables locating the origin and energy of trap states in six state‐of‐the‐art polymer – non‐fullerene acceptor organic photodiodes (OPDs) with noise‐based specific detectivities exceeding 1013 Jones. Analyzing the temperature dependence of the reverse‐bias dark current density (Jd) identifies intra‐gap states in the polymers, lying 0.3−0.4 eV above the energy of the highest occupied molecular orbital, as being responsible for Jd. Sub‐bandgap external quantum efficiency spectra of donor‐only and acceptor‐only diodes confirm that intra‐gap states are much more abundant in the polymers. Likewise, responsivity measurements at ultra‐low light intensities (10−7 mW cm−2) show trap‐mediated charge recombination in BHJ and polymer‐only diodes, but not in acceptor‐only devices. The results imply that to further improve the specific detectivity of near‐infrared OPDs, the intra‐gap state energy, and density need to be reduced.