bluuebunny/crossref_metadata_2025_split huggingface dataset:
High-mountain phylogeography in the Balkan Peninsula: isolation pattern in a species of alpine siliceous grasslands and its possible background
Authors: Ronikier Michał , Kuzmanović Nevena , Lakušić Dmitar , Stevanoski Ivana , Nikolov Zoran , Zimmermann Niklaus E. 
Published: July 2023

AbstractAlthough the Balkan Peninsula belongs to the most mountainous regions of Europe, phylogeographic structure of its alpine flora remains insufficiently understood, especially for species distributed both in the western and eastern parts of the Peninsula. We analyzed Campanula orbelica, a Balkan endemic typical of high-mountain siliceous grasslands, based on the population genetic structure, climatic niche modeling at the species- and intraspecific level, and niche hindcasting back to the Last Glacial Maximum (LGM; 20 kya). Our data reveal a clear phylogeographic pattern with three geographically coherent genetic groups: (i) the most divergent and spatially restricted lineage of the Pirin mountains (east), (ii) neighboring Rila mountains and other eastern Balkan massifs (Rhodopes, Stara Planina, Vitoša), and (iii) the most geographically disjunct mountains of the Scardo-Pindhic range (Šar Planina and Korab) in the west. This pattern indicates multiple refugia and isolated evolutionary centers within the Balkan Peninsula mountains, with the eastern part of the range as likely ancestral area, and an early dispersion into the western region, which formed the main geographical disjunction. The genetic divergence was only partly correlated with geographical isolation, clear dispersal barriers, or climatic niche shifts, suggesting contrasting isolation/dispersal dynamics in various parts of the range. Climatic niche overlap was low among eastern vs. western groups, which correlates with the longest spatial distance and significant genetic divergence, while niche characteristic of the Pirin lineage was a subset of the adjacent Rila lineage niche. High genetic divergence of the Pirin populations was also not correlated with persistent gaps in potential distributions but hypothetically may have been triggered by diversified (limestone/silicate) bedrock conditions. Our results highlight the need for high-mountain phylogeographic surveys in the eastern part of the Balkan Peninsula, to assess the biogeographical relevance of isolation patterns and definition of evolutionarily important units in the high-mountain flora.
A major yellow rust resistance QTL on chromosome 6A shows increased frequency in recent Norwegian spring wheat cultivars and breeding lines
Authors: Lin Min , Dieseth Jon Arne , Alsheikh Muath , Yang Ennian , Holzapfel Josef , Schürmann Friederike , Morales Laura , Michel Sebastian , Buerstmayr Hermann , Bhavani Sridhar , Lillemo Morten 
Published: July 2023

Abstract
Key message
A major yellow rust resistance QTL, QYr.nmbu.6A, contributed consistent adult plant resistance in field trials across Europe, China, Kenya and Mexico.

Abstract
Puccinia striiformis f. sp. tritici, causing wheat yellow rust (YR), is one of the most devastating biotrophic pathogens affecting global wheat yields. Owing to the recent epidemic of the PstS10 race group in Europe, yellow rust has become a reoccurring disease in Norway since 2014. As all stage resistances (ASR) (or seedling resistances) are usually easily overcome by pathogen evolution, deployment of durable adult plant resistance (APR) is crucial for yellow rust resistance breeding. In this study, we assessed a Nordic spring wheat association mapping panel (n = 301) for yellow rust field resistance in seventeen field trials from 2015 to 2021, including nine locations in six countries across four different continents. Nine consistent QTL were identified across continents by genome-wide association studies (GWAS). One robust QTL on the long arm of chromosome 6A, QYr.nmbu.6A, was consistently detected in nine out of the seventeen trials. Haplotype analysis of QYr.nmbu.6A confirmed significant QTL effects in all tested environments and the effect was also validated using an independent panel of new Norwegian breeding lines. Increased frequency of the resistant haplotype was found in new varieties and breeding lines in comparison to older varieties and landraces, implying that the resistance might have been selected for due to the recent changes in the yellow rust pathogen population in Europe.
Mutuality as a method: advancing a social paradigm for global mental health through mutual learning
Authors: Bemme Dörte , Roberts Tessa , Ae-Ngibise Kenneth A. , Gumbonzvanda Nyaradzayi , Joag Kaustubh , Kagee Ashraf , Machisa Mercilene , van der Westhuizen Claire , van Rensburg André , Willan Samantha , Wuerth Milena , Aoun May , Jain Sumeet , Lund Crick , Mathias Kaaren , Read Ursula , Taylor Salisbury Tatiana , Burgess Rochelle A. 
Published: July 2023

Abstract
Purpose
Calls for “mutuality” in global mental health (GMH) aim to produce knowledge more equitably across epistemic and power differences. With funding, convening, and publishing power still concentrated in institutions in the global North, efforts to decolonize GMH emphasize the need for mutual learning instead of unidirectional knowledge transfers. This article reflects on mutuality as a concept and practice that engenders sustainable relations, conceptual innovation, and queries how epistemic power can be shared.

Methods
We draw on insights from an online mutual learning process over 8 months between 39 community-based and academic collaborators working in 24 countries. They came together to advance the shift towards a social paradigm in GMH.

Results
Our theorization of mutuality emphasizes that the processes and outcomes of knowledge production are inextricable. Mutual learning required an open-ended, iterative, and slower paced process that prioritized trust and remained responsive to all collaborators’ needs and critiques. This resulted in a social paradigm that calls for GMH to (1) move from a deficit to a strength-based view of community mental health, (2) include local and experiential knowledge in scaling processes, (3) direct funding to community organizations, and (4) challenge concepts, such as trauma and resilience, through the lens of lived experience of communities in the global South.

Conclusion
Under the current institutional arrangements in GMH, mutuality can only be imperfectly achieved. We present key ingredients of our partial success at mutual learning and conclude that challenging existing structural constraints is crucial to prevent a tokenistic use of the concept.
Trajectories of psychological distress and social integration in newly resettled refugees: findings from the Building a New Life in Australia longitudinal study
Authors: Nguyen Thomas P. , Slewa-Younan Shameran , Rioseco Pilar 
Published: July 2023

Abstract
Purpose
Refugees are at greater risk of mental illness due to stressors encountered post-resettlement. However, few longitudinal studies have examined the within-person effects of these stressors, especially with respect to social integration. This study aims to examine what factors are associated with psychological distress in a longitudinal sample of refugees resettled in Australia.

Methods
This study used data from three Waves of the Building a New Life in Australia study, collected between 2013 and 2018. The eligible sample included 1881 adult respondents, clustered in 1175 households. We conducted multilevel mixed-effects growth modelling incorporating time-variant and time-invariant covariates with psychological distress, using the Kessler Psychological Distress Scale (K6).

Results
Rates of high psychological distress increased across the 5-year follow-up period. Social integration stressors (e.g. discrimination, lower sense of belonging, loneliness, lower English proficiency) were associated with higher levels of psychological distress over time. Refugees reporting loneliness not only had a greater risk of elevated psychological distress at each time point, but the difference in risk increased over each time point. Refugees who were exposed to traumatic events, older, female and of Middle Eastern background were also more likely to report higher levels of psychological distress over time.

Conclusions
These findings highlight the importance of identifying refugees who may encounter difficulties with social integration in the early years of resettlement. Newly arrived refugees may benefit from longer-term resettlement programmes that address post-migratory stressors, particularly with regards to loneliness, to reduce the prevalence of elevated psychological distress during the early years of resettlement.
Ecological footprint, electricity consumption, and economic growth in China: geopolitical risk and natural resources governance
Authors: Magazzino Cosimo 
Published: July 2023

AbstractThis paper examines the relationship among ecological footprint (EF), electricity consumption, and GDP in China using annual data ranging from 1960 to 2019. However, factors like trade openness, urbanization, and life expectancy might increase EF as ecological distortions are mainly human-induced. This study explores the effect of these variables on the environment, which is captured by EF. Quantile Regression estimates indicate that electricity consumption and real GDP increase environmental degradation, while trade and urbanization reduce EF, allowing for a higher environmental quality. On the other hand, the spectral Granger-causality tests reveal that only urbanization and life expectancy affect environmental degradation over the whole frequency domain. In the current geopolitical scenario, relevant policy implications may be derived.
Can vaginal lactobacillus suppositories help reduce urinary tract infections?
Authors: Shoureshi Poone S. , Niino Clarissa , Eilber Karyn S. 
Published: July 2023

Abstract
Introduction and hypothesis
Recurrent urinary tract infections (rUTIs) are a burden to patients and the health care economy. Vaginal probiotics and supplements have gained significant attention in mainstream media and lay press as a non-antibiotic alternative. We performed a systematic review to determine whether vaginal probiotics are an effective means of prophylaxis for rUTI.

Methods
A PubMed/MEDLINE article search was performed from inception to August 2022 for prospective, in vivo use of vaginal suppositories for the prevention of rUTIs. Search terms included: vaginal probiotic suppository (34 results), vaginal probiotic randomized (184 results), vaginal probiotic prevention (441 results), vaginal probiotic UTI (21 results), and vaginal probiotic urinary tract infection (91 results). A total of 771 article titles and abstracts were screened.

Results
A total of 8 articles fit the inclusion criteria and were reviewed and summarized. Four were randomized controlled trials, with 3 of the studies having a placebo arm. Three were prospective cohort studies, and 1 was a single arm, open label trial. Five of the 7 articles that specifically evaluated for rUTI reduction with vaginal suppositories did find a decreased incidence with probiotic use; however, only 2 had statistically significant results. Both of these were studies of Lactobacillus crispatus and were not randomized. Three studies demonstrated the efficacy and safety of Lactobacillus as a vaginal suppository.

Conclusion
Current data support the use of vaginal suppositories containing Lactobacillus as a safe, non-antibiotic measure, but actual reduction of rUTI in susceptible women remains inconclusive. The appropriate dosing and duration of therapy remain unknown.
Gynecologists’ perspectives on surgical treatment for apical prolapse: a qualitative study
Authors: van Oudheusden Anique M. J. , Weemhoff Mirjam , Menge Leah F. , Essers Brigitte A. B. 
Published: July 2023

Abstract
Introduction and hypothesis
Vaginal sacrospinous fixation (VSF) without mesh and sacrocolpopexy (SCP) with mesh are the most frequently performed surgical procedures for apical prolapse in the Netherlands. There is no long-term evidence suggesting the optimal technique, however. The aim was to identify which factors play a role in the choice between these surgical treatment options.

Methods
A qualitative study using semi-structured interviews amongst Dutch gynecologists was carried out. An inductive content analysis was performed with Atlas.ti.

Results
Ten interviews were analyzed. All gynecologists performed vaginal surgeries for apical prolapse, six gynecologists perform SCP themselves. Six gynecologists would perform VSF for a primary vaginal vault prolapse (VVP); three gynecologists preferred a SCP. All participants prefer a SCP for recurrent VVP. All participants have stated that multiple comorbidities could be a reason for choosing VSF, as this procedure is considered less invasive. Most participants choose a VSF in the case of older age (6 out of 10) or higher body mass index (7 out of 10). All treat primary uterine prolapse with vaginal, uterine-preserving surgery.

Conclusions
Recurrent apical prolapse is the most important factor in advising patients which treatment they should undergo for VVP or uterine descent. Also, the patient’s health status and the patient’s own preference are important factors. Gynecologists who do not perform the SCP in their own clinic are more likely to perform a VSF and find more reasons not to advise a SCP. All participants prefer a vaginal surgery for a primary uterine prolapse.
Determining the impact of seasoning on the volatile chemical composition of the oak wood of different Sherry Casks® by DTD–GC–MS
Authors: Guerrero-Chanivet María , García-Moreno M. Valme , Valcárcel-Muñoz Manuel J. , Guillén-Sánchez Dominico A. 
Published: July 2023

AbstractThe casks that have contained for a certain time Sherry wines are known as Sherry Casks® and their use and value have increased in recent years, as they confer unique organoleptic properties to the distillates and beverages that are aged inside them. During their seasoning, these casks yield certain compounds from wood into the wines, and at the same time, they retain some compounds from these Sherry wines which, in turn, are transferred to the distillates that are aged inside the casks, so that wood acts as a transfer vector between the two alcoholic beverages. A characterization of seasoned staves with three Sherry wines, Fino, Oloroso, and Pedro Ximénez, by DTD–GC–MS has been carried out in this study. Different tendencies regarding the compounds present in the wood have been observed as follows: in general, certain compounds from wood either disappeared or decreased during its seasoning, while other compounds that come from the seasoning wine either increased or appeared in the wood during the seasoning process. This fact demonstrates that during the ageing of Sherry wines these transfer certain interesting compounds into the casks wood, which are in turn transferred to the distillates.
Diffusive mass transfer and protein removal in the alkaline cleaning of a jellylike whey protein fouling layer
Authors: Wiese H. , Geißler H. , Augustin W. , Scholl S. 
Published: July 2023

AbstractSingle steps in cleaning a fouled heat exchanger surface eventually determine the cleaning kinetic and thus the overall performance of a cleaning process. Up to date the complex mechanisms of the mutual supportive processes in cleaning are not yet fully understood. This contribution presents a stepwise approach to investigate the individual process steps starting with the diffusion of the cleaning agent NaOH into a WPI gel, studied at stationary and flow conditions. In the experiments, temperature affected both the diffusion step and the subsequent removal but to different extents. This was further specified and it was found that there is an induction time for the release of disengaged proteins, accounting for the speed of the temperature dependent degrading reactions.
Long-term impact of myocardial inflammation on quantitative myocardial perfusion—a descriptive PET/MR myocarditis study
Authors: Buechel Ronny R. , Ciancone Domenico , Bakula Adam , von Felten Elia , Schmidt Gian-Andrea , Patriki Dimitri , Gräni Christoph , Wahl Andreas , Manka Robert , Heidecker Bettina , Benz Dominik C. , Giannopoulos Andreas A. , Pazhenkottil Aju P. , Kaufmann Philipp A. 
Published: July 2023

AbstractPurposeWhether myocardial inflammation causes long-term sequelae potentially affecting myocardial blood flow (MBF) is unknown. We aimed to assess the effect of myocardial inflammation on quantitative MBF parameters, as assessed by 13N-ammonia positron emission tomography myocardial perfusion imaging (PET-MPI) late after myocarditis.MethodsFifty patients with a history of myocarditis underwent cardiac magnetic resonance (CMR) imaging at diagnosis and PET/MR imaging at follow-up at least 6 months later. Segmental MBF, myocardial flow reserve (MFR), and 13N-ammonia washout were obtained from PET, and segments with reduced 13N-ammonia retention, resembling scar, were recorded. Based on CMR, segments were classified as remote (n = 469), healed (inflammation at baseline but no late gadolinium enhancement [LGE] at follow-up,n = 118), and scarred (LGE at follow-up,n = 72). Additionally, apparently healed segments but with scar at PET were classified as PET discordant (n = 18).ResultsCompared to remote segments, healed segments showed higher stress MBF (2.71 mL*min−1*g−1[IQR 2.18–3.08] vs. 2.20 mL*min−1*g−1[1.75–2.68],p < 0.0001), MFR (3.78 [2.83–4.79] vs. 3.36 [2.60–4.03],p < 0.0001), and washout (rest 0.24/min [0.18–0.31] and stress 0.53/min [0.40–0.67] vs. 0.22/min [0.16–0.27] and 0.46/min [0.32–0.63],p = 0.010 andp = 0.021, respectively). While PET discordant segments did not differ from healed segments regarding MBF and MFR, washout was higher by ~ 30% (p < 0.014). Finally, 10 (20%) patients were diagnosed by PET-MPI as presenting with a myocardial scar but without a corresponding LGE.ConclusionIn patients with a history of myocarditis, quantitative measurements of myocardial perfusion as obtained from PET-MPI remain altered in areas initially affected by inflammation.Graphical abstractCMR = cardiac magnetic resonance; PET = positron emission tomography; LGE = late gadolinium enhancement
Sound velocity and elastic properties of Fe–Ni–S–Si liquid: the effects of pressure and multiple light elements
Authors: Yamada Iori , Terasaki Hidenori , Urakawa Satoru , Kondo Tadashi , Machida Akihiko , Tange Yoshinori , Higo Yuji 
Published: July 2023

AbstractFe–Ni–S–Si alloy is considered to be one of the plausible candidates of Mercury core material. Elastic properties of Fe–Ni–S–Si liquid are important to reveal the density profile of the Mercury core. In this study, we measured the P-wave velocity (VP) of Fe–Ni–S–Si (Fe73Ni10S10Si7, Fe72Ni10S5Si13, and Fe67Ni10S10Si13) liquids up to 17 GPa and 2000 K to study the effects of pressure, temperature, and multiple light elements (S and Si) on the VP and elastic properties.The VP of Fe–Ni–S–Si liquids are less sensitive to temperature. The effect of pressure on the VP are close to that of liquid Fe and smaller than those of Fe–Ni–S and Fe–Ni–Si liquids. Obtained elastic properties are KS0 = 99.1(9.4) GPa, KS’ = 3.8(0.1) and ρ0 =6.48 g/cm3 for S-rich Fe73Ni10S10Si7 liquid and KS0 = 112.1(1.5) GPa, KS’ = 4.0(0.1) and ρ0=6.64 g/cm3 for Si-rich Fe72Ni10S5Si13 liquid. The VP of Fe–Ni–S–Si liquids locate in between those of Fe–Ni–S and Fe–Ni–Si liquids. This suggests that the effect of multiple light element (S and Si) on the VP is suppressed and cancel out the effects of single light elements (S and Si) on the VP. The effect of composition on the EOS in the Fe–Ni–S–Si system is indispensable to estimate the core composition combined with the geodesy data of upcoming Mercury mission.
A convenient scoring system to distinguish intrahepatic mass-forming cholangiocarcinoma from solitary colorectal liver metastasis based on magnetic resonance imaging features
Authors: Shen Keren , Mo Weixing , Wang Xiaojie , Shi Dan , Qian Wei , Sun Jihong , Yu Risheng 
Published: July 2023

Abstract
Objectives
To develop and validate a diagnostic scoring system to differentiate intrahepatic mass-forming cholangiocarcinoma (IMCC) from solitary colorectal liver metastasis (CRLM).

Methods
A total of 366 patients (263 in the training cohort, 103 in the validation cohort) who underwent MRI examination with pathologically proven either IMCC or CRLM from two centers were included. Twenty-eight MRI features were collected. Univariate analyses and multivariate logistic regression analyses were performed to identify independent predictors for distinguishing IMCC from solitary CRLM. The independent predictors were weighted over based on regression coefficients to build a scoring system. The overall score distribution was divided into three groups to show the diagnostic probability of CRLM.

Results
Six independent predictors, including hepatic capsular retraction, peripheral hepatic enhancement, vessel penetrating the tumor, upper abdominal lymphadenopathy, peripheral washout at the portal venous phase, and rim enhancement at the portal venous phase were included in the system. All predictors were assigned 1 point. At a cutoff of 3 points, AUCs for this score model were 0.948 and 0.903 with sensitivities of 96.5% and 92.0%, specificities of 84.4% and 71.7%, positive predictive values of 87.7% and 75.4%, negative predictive values of 95.4% and 90.5%, and accuracies of 90.9% and 81.6% for the training and validation cohorts, respectively. An increasing trend was shown in the diagnostic probability of CRLM among the three groups based on the score.

Conclusions
The established scoring system is reliable and convenient for distinguishing IMCC from solitary CRLM using six MRI features.

Clinical relevance statement
A reliable and convenient scoring system was developed to differentiate between intrahepatic mass-forming cholangiocarcinoma from solitary colorectal liver metastasis using six MRI features.

Key Points
• Characteristic MRI features were identified to distinguish intrahepatic mass-forming cholangiocarcinoma (IMCC) from solitary colorectal liver metastasis (CRLM).
• A model to distinguish IMCC from solitary CRLM was created based on 6 features, including hepatic capsular retraction, upper abdominal lymphadenopathy, peripheral washout at the portal venous phase, rim enhancement at the portal venous phase, peripheral hepatic enhancement, and vessel penetrating the tumor.