bluuebunny/crossref_metadata_2025_split huggingface dataset:
Infection with wild-type SARS-CoV-2 elicits broadly neutralizing and protective antibodies against omicron subvariants
Authors: Ju Bin , Zhang Qi , Wang Ziyi , Aw Zhen Qin , Chen Peng , Zhou Bing , Wang Ruoke , Ge Xiangyang , Lv Qining , Cheng Lin , Zhang Rui , Wong Yi Hao , Chen Huixin , Wang Haiyan , Shan Sisi , Liao Xuejiao , Shi Xuanling , Liu Lei , Chu Justin Jang Hann , Wang Xinquan , Zhang Zheng , Zhang Linqi 
Published: March 2023

AbstractThe omicron variants of SARS-CoV-2 have substantial ability to escape infection- and vaccine-elicited antibody immunity. Here, we investigated the extent of such escape in nine convalescent patients infected with the wild-type SARS-CoV-2 during the first wave of the pandemic. Among the total of 476 monoclonal antibodies (mAbs) isolated from peripheral memory B cells, we identified seven mAbs with broad neutralizing activity to all variants tested, including various omicron subvariants. Biochemical and structural analysis indicated the majority of these mAbs bound to the receptor-binding domain, mimicked the receptor ACE2 and were able to accommodate or inadvertently improve recognition of omicron substitutions. Passive delivery of representative antibodies protected K18-hACE2 mice from infection with omicron and beta SARS-CoV-2. A deeper understanding of how the memory B cells that produce these antibodies could be selectively boosted or recalled can augment antibody immunity against SARS-CoV-2 variants.
Unfolding and modeling the recovery process after COVID lockdowns
Authors: Yang Xuan , Yang Yang , Tan Chenhao , Lin Yinghe , Fu Zhengzhe , Wu Fei , Zhuang Yueting 
Published: March 2023

AbstractLockdown is a common policy used to deter the spread of COVID-19. However, the question of how our society comes back to life after a lockdown remains an open one. Understanding how cities bounce back from lockdown is critical for promoting the global economy and preparing for future pandemics. Here, we propose a novel computational method based on electricity data to study the recovery process, and conduct a case study on the city of Hangzhou. With the designed Recovery Index, we find a variety of recovery patterns in main sectors. One of the main reasons for this difference is policy; therefore, we aim to answer the question of how policies can best facilitate the recovery of society. We first analyze how policy affects sectors and employ a change-point detection algorithm to provide a non-subjective approach to policy assessment. Furthermore, we design a model that can predict future recovery, allowing policies to be adjusted accordingly in advance. Specifically, we develop a deep neural network, TPG, to model recovery trends, which utilizes the graph structure learning to perceive influences between sectors. Simulation experiments using our model offer insights for policy-making: the government should prioritize supporting sectors that have greater influence on others and are influential on the whole economy.
Research on non-cohesive jet formed by Zr-based amorphous alloys
Authors: Shi Jin , Huang Zhengxiang , Zu Xudong , Xiao Qiangqiang , Wang Yuting 
Published: March 2023

AbstractThe shaped charge jet formation of a Zr-based amorphous alloy and the applicability of different numerical algorithms to describe the jet formed were experimentally and numerically investigated. X-ray experiments were performed to study jet characteristics. The numerical results for the Zr-based amorphous alloy jet formed via the Euler and smooth particle hydrodynamics (SPH) algorithms were compared and analyzed using the Autodyn hydrocode. Particle motion was examined based on material properties. The Zr-based amorphous alloy formed a noncohesive jet driven by an 8701 explosive. Both the Euler and SPH algorithms achieved high accuracy for the determination of jet velocity. When the improved Johnson-Holmquist constitutive model (JH-2) was used, numerical results confirmed the model’s suitability for the Zr-based amorphous alloy. The Euler algorithm effectively reflected jet shape within a short computing time, whereas the SPH algorithm was highly suitable for showing the shape of the jet tail within a long computing time. In the 3D Euler model, the flared jet mouth indicated radial particle dispersion; however, in the 2D model, particle dispersion in the head was directly observed by using the JH-2 material model. The brittle fracture of the material reduced the proportion of particles near the liner apex forming a jet. Furthermore, a new method in which stagnation pressure was used to predict jet formation and its coherence was proposed since the collapse angle was difficult to obtain.
Effect of thermal radiation on convective heat transfer in MHD boundary layer Carreau fluid with chemical reaction
Authors: Shah Syed Amir Ghazi Ali , Hassan Ali , Karamti Hanen , Alhushaybari Abdullah , Eldin Sayed M. , Galal Ahmed M. 
Published: March 2023

AbstractThe temperature dependent thermophysical fluid properties have numerous aspects in different industries and engineering processes in which heat transmission is based on fluid flow. For such heat transmission processes, heat transmission system is highly fluctuated with variation of viscosity. Thus, the aim of this study is to investigate the transfer of heat in magnetized Carreau fluid with chemical reaction and under influence of thermal radiation over nonlinear stretching/shrinking surface. Additionally, we have incorporated variable heat dependent thermophysical properties to analyze the heat transfer in magnetized Carreau fluid. Set of flow governing non linear PDE’s are obtained using Carreau fluid tensor and boundary layer approximation (BLA) theory. Dimensionless set of ODE’s are obtained using suitable similarity transforms. Shooting method in conjunction with Newton's method have been utilized to solve the problem. It is noted that when stretching $$B\ge 0$$

B
≥
0

is significant with strictly increasing mass suction $$S$$
S
shear stress rate increase with minor levels and sharp increase has been observed in Nusselt number, whereas in shrinking case $$B<0$$

B
<
0

shear stress and heat transfer coefficient values are improved raising the value of $$S$$
S
mass suction. Further, raising the values of power law index $$n$$
n
produce reduced skin friction over stretching surface $$B\ge 0$$

B
≥
0

while skin friction dramatically enhance in shrinking case $$B<0$$

B
<
0

. It is observed that raising the non-linearity $$m$$
m
values for stretching or shrinking, skin friction and Nusselt number considerably improved. Moreover, computational outcomes of the study are validated with already published previous results and the results obtained in this study are found in good agreement.
Research on main influencing factors and complete support technology for dynamic pressure and large deformation roadway
Authors: Rong Hai , Guo Kaipeng , Sun Dequan , Luo Mingkun , Dong Wei , Huo Bingjie 
Published: March 2023

AbstractTo determine the main factors influencing dynamic pressure and large deformation roadways, a targeted set of support technologies was designed. The 2603 air inlet roadway of the Zhangcun coal mine in Lu'an, Shanxi Province, was taken as an example. The influence of the Wenwangshan South normal fault and in situ stress field on the dynamic pressure roadway was analyzed theoretically, and the main factors influencing this dynamic pressure and large deformation roadway under natural geological conditions were determined. The effect of the existing roadway support scheme was evaluated by field test methods such as nondestructive bolt testing. The influence of mining two working faces on the dynamic pressure and large deformation roadway was studied by the FLAC3D numerical simulation method. On this basis, a new grouting material was developed, a complete set of technical schemes of full-section integrated cooperative support of dynamic pressure and large deformation roadways was proposed, and the field application effect was verified. The results showed that under natural geological conditions, the 2603 air inlet roadway was located within the influence range of the Wenwangshan South normal fault, which was significantly affected and controlled by the fault. The included angle between the roadway extension direction and the maximum principal stress was 74°, which was not conducive to the stability of the roadway. The range of the roadway loose zone was large. Under the existing support conditions, the surrounding rock could not form a relatively stable structure, which was one of the main reasons for the large deformation of the surrounding rock in the dynamic pressure roadway. The 2603 air inlet roadway was affected by the mining of both the adjacent working face and the 2603 working face. The stresses were superimposed, and the roadway was greatly deformed and damaged. A new grouting material was developed. A crosslinking agent prepared by toluene diisocyanate and polyether polyol was added to the existing polyurethane material to form a new grouting material, and a complete supporting technical scheme was proposed. The field application results showed that the displacement and floor heave of both sides of the roadway were reduced by approximately 87%, the deformation and failure of the coal and rock mass of the roadway were effectively controlled, and the deformation of the dynamic pressure roadway was greatly reduced.
Nickel substituted polyoxometalates in layered double hydroxides as metal-based nanomaterial of POM–LDH for green catalysis effects
Authors: Ghiasi Moaser Azra , Afkham Ahmad Gholami , Khoshnavazi Roushan , Rostamnia Sadegh 
Published: March 2023

AbstractThree nickel substituted Keggin-type polyoxometalates, α-[SiW9O37{Ni(H2O)}3]−10 (denoted as SiW9Ni3), was intercalated into Zn3Al based Layered Double Hydroxide (Zn3Al-LDH) by the selective ion-exchange technique. The as-synthesized nanocomposite, SiW9Ni3@Zn3Al, was used as heterogeneous nanoreactor to promote the synthesis of drug-like aminoimidazopyridine small molecule skeletons via the well-known Ugi-type Groebke–Blackburn–Bienaymé reaction (GBB 3-CRs) in the absence of any acid/additive and under mild and solvent-free conditions. A synergistic catalytic effect between SiW9Ni3 polyoxometalate and Zn3Al-LDH precursors is evidenced by a higher catalytic property of the SiW9Ni3@Zn3Al composite compared to the individual constituents separately. Lewis/Bronsted acidity of the SiW9Ni3 polyoxometalate and Zn3Al-LDH precursors appear to be essential for the catalytic performance of the composite. Furthermore, the catalytic performance of SiW9Ni3@Zn3Al was also tested in GBB 3-CRs synthesis of amino imidazothiazole under mild and solvent-free conditions.
The remineralization effect of GERM CLEAN on early human enamel caries lesions in vitro
Authors: Wang Ye , Xiong Kaixin , Chen Xuan , Chi Yaqi , Han Qi , Zou Ling 
Published: March 2023

AbstractThis study aimed to evaluate the remineralization effect of GERM CLEAN, a novel antibacterial peptide, on early enamel caries. Thirty human enamel blocks from thirty teeth were randomly divided into three groups: double distilled water (DDW group), GERM CLEAN (GC group), and 1000 ppm fluoride (NaF group). Specimens were demineralized for 3 days (pH 4.6) followed by pH cycling twice daily for 14 days. For a pH cycle, specimens received corresponding treatments for 5 min, then were immersed in demineralizing solution for 1 h, received corresponding treatments again, and finally were immersed in remineralizing solution (pH 7.0) for approximately 11 h. Specimens were washed with DDW after each treatment. Microindentation tests, atomic force microscopy (AFM), and transverse micro-radiography (TMR) were conducted to analyze enamel blocks. GC demonstrated a lower percentage of surface microhardness recovery (SMHR%) (p < 0.0001), rougher surfaces (p < 0.0001), deeper lesion depth (p = 0.001), and more mineral loss (p = 0.001) than NaF, but showed higher SMHR% (p < 0.0001), smoother surfaces (p < 0.0001), shallower lesion depth (p = 0.049), and less mineral loss (p = 0.001) than DDW. As a result, GERM CLEAN has the potential to promote the remineralization of demineralized enamel.
In silicomodelling of the function of disease-related CAZymes
Authors: Nin-Hill Alba , Piniello Beatriz , Rovira Carme 
Published: March 2023

AbstractIn silico modelling of proteins comprises a diversity of computational tools aimed to obtain structural, electronic, and/or dynamic information about these biomolecules, capturing mechanistic details that are challenging to experimental approaches, such as elusive enzyme-substrate complexes, short-lived intermediates, and reaction transition states (TS). The present article gives the reader insight on the use of in silico modelling techniques to understand complex catalytic reaction mechanisms of carbohydrate-active enzymes (CAZymes), along with the underlying theory and concepts that are important in this field. We start by introducing the significance of carbohydrates in nature and the enzymes that process them, CAZymes, highlighting the conformational flexibility of their carbohydrate substrates. Three commonly used in silico methods (classical molecular dynamics (MD), hybrid quantum mechanics/molecular mechanics (QM/MM), and enhanced sampling techniques) are described for nonexpert readers. Finally, we provide three examples of the application of these methods to unravel the catalytic mechanisms of three disease-related CAZymes: β-galactocerebrosidase (GALC), responsible for Krabbe disease; α-mannoside β-1,6-N-acetylglucosaminyltransferase V (MGAT5), involved in cancer; and O-fucosyltransferase 1 (POFUT1), involved in several human diseases such as leukemia and the Dowling–Degos disease.
A low‐profile wideband spiral antenna with multiple stopbands
Authors: Tanabe Masahiro , Nakano Hisamatsu 
Published: March 2023

AbstractA low‐profile spiral antenna with three stopbands (2.55 GHz band, 3.85 GHz band, and 5.45 GHz band) is developed. The stopbands are generated using three pairs of slots cut into the spiral arms. The antenna height is 0.077 wavelength at a low band edge frequency of 2 GHz. Firstly, the effects of the slot dimensions (length, width, ending angle, and position) on the stopbands are analysed, where the spiral antenna floating in free space radiates a bi‐directional beam. It is found that the stopband centre frequency is determined by the slot length, and the stopband bandwidth is determined by the slot width, ending angle, and position. Secondly, the fabrication tolerances are investigated. Thirdly, the bi‐directional beam from the floating spiral antenna is transformed into a unidirectional beam by using a low‐profile cavity. It is revealed that three stopbands are maintained. Finally, a prototype of the antenna is fabricated and measured to verify the analysed results.
Sociology and hierarchy of voids: A study of seven nearby CAVITY galaxy voids and their dynamical CosmicFlows-3 environment
Authors: Courtois H. M. , van de Weygaert R. , Aubert M. , Pomarède D. , Guinet D. , Domínguez-Gómez J. , Florido E. , Galbany L. , García-Benito R. , van der Hulst J. M. , Kreckel K. , Miura R. E. , Pérez I. , Planelles S. , Quilis V. , Román J. , Sánchez-Portal M. 
Published: March 2023

Context. The present study addresses a key question related to our understanding of the relation between void galaxies and their environment: the relationship between luminous and dark matter in and around voids.
Aims. To explore the extent to which local Universe voids are empty of matter, we study the full (dark+luminous) matter content of seven nearby cosmic voids that are fully contained within the CosmicFlows-3 volume.
Methods. We obtained the matter-density profiles of seven cosmic voids using two independent methods. These were built from the galaxy redshift space two-point correlation function in conjunction with peculiar velocity gradients from the CosmicFlows-3 dataset.
Results. The results are striking, because when the redshift survey is used, all voids show a radial positive gradient of galaxies, while based on the dynamical analysis, only three of these voids display a clear underdensity of matter in their center.
Conclusions. This work constitutes the most detailed observational analysis of voids conducted so far, and shows that void emptiness should be derived from dynamical information. From this limited study, the Hercules void appears to be the best candidate for a local Universe pure “pristine volume”, expanding in three directions with no dark matter located in that void.
„Psychiatrie on tour“: was bleibt, was muss sich
– jetzt – ändern?
Authors: Steinhart Ingmar , Stengler Katarina 
Published: March 2023

Worum es gehtSpätestens seit der Corona-Pandemie hat das Thema Krise in der
Versorgungslandschaft in Deutschland, so auch in der Psychiatrie, Konjunktur. Und
wir erkennen, an welchen Stellen die Psychiatrie eher robust oder eher
„anfällig“ aufgestellt war – und heute noch ist.
Red-listed plants are contracting their elevational range faster than common plants in the European Alps
Authors: Geppert Costanza , Bertolli Alessio , Prosser Filippo , Marini Lorenzo 
Published: March 2023

Mountain ecosystems are exposed to multiple anthropogenic pressures that are reshaping the distribution of plant populations. Range dynamics of mountain plants exhibit large variability with species expanding, shifting, or shrinking their elevational range. Using a dataset of more than 1 million records of common and red-listed native and alien plants, we could reconstruct range dynamics of 1,479 species of the European Alps over the last 30 y. Red-listed species were not able to track climate warming at the leading edge of their distribution, and further experienced a strong erosion of rear margins, resulting in an overall rapid range contraction. Common natives also contracted their range, albeit less drastically, through faster upslope shift at the rear than at the leading edge. By contrast, aliens quickly expanded upslope by moving their leading edge at macroclimate change speed, while keeping their rear margins almost still. Most red-listed natives and the large majority of aliens were warm-adapted, but only aliens showed high competitive abilities to thrive under high-resource and disturbed environments. Rapid upward shifts of the rear edge of natives were probably driven by multiple environmental pressures including climate change as well as land-use change and intensification. The high environmental pressure that populations encounter in the lowlands might constrain the ability of expanding species to shift their range into more natural areas at higher elevations. As red-listed natives and aliens mostly co-occurred in the lowlands, where human pressures are at their highest, conservation should prioritize low-elevation areas of the European Alps.
Migration, Europe, and the question of political and economic sovereignty in Africa
Authors: Cross Hannah 
Published: March 2023

SUMMARY
This debate piece argues for the importance of labour internationalism and anti-imperialism in the anti-racist defence of migrants. A focus on the Sahel region shows some of the ways that core European states militarily, economically and politically undermine countries’ potential for self-determination. Border regimes, their modes of accumulation and selective labour policies expand militarism, social division and inequality between and within the regions. Challenges to these processes of global apartheid require attention to the national question and rejection of European imperialism, as indicated in recent pan-African calls for independence and popular sovereignty. This materialist analysis of migration in capitalism presents a basis for demanding equality of movement and the freedom and equality of societies facing capitalism-induced displacement.
Polarized fusion and potential in situ tests of fuel polarization survival in a tokamak plasma
Authors: Baylor L. , Deur A. , Eidietis N. , Heidbrink W.W. , Jackson G.L. , Liu J. , Lowry M.M. , Miller G.W. , Pace D. , Sandorfi A.M. , Smith S.P. , Tafti S. , Wei K. , Wei X. , Zheng X. 
Published: March 2023

Abstract
The use of spin-polarized fusion fuels would provide a significant boost towards the ignition of a burning plasma. The cross section for D + T → α + n, would be increased by 1.5 if the fuels were injected with parallel polarization. Furthermore, our simulations demonstrate additional non-linear power gains in large-scale machines such as ITER, due to increased alpha heating. Such benefits require the survival of spin polarizations for periods comparable to the particle confinement time. During the 1980s, calculations predicted that polarizations could survive a plasma environment, although concerns persisted regarding the cumulative impacts of wall recycling. In that era, technical challenges prevented direct tests and left the large scale fueling of a power reactor beyond reach. Over the last decades, this situation has changed dramatically. Detailed simulations of ITER have predicted negligible wall recycling in a high-power reactor, and recent advances in laser-driven sources project the capability of producing large quantities of ∼100% polarized D and T. The remaining crucial step is an in-situ demonstration of polarization survival in a plasma. For this, we outline a measurement strategy using the isospin-mirror reaction, D + 3He → α + p. Polarized 3He avoids the complexities of handling tritium, while encompassing the same spin-physics. We evaluate two methods of delivering deuterium, using dynamically polarized Lithium-Deuteride (with vector polarization PV
D of 70%) or frozen-spin Hydrogen-Deuteride (with PV
D of 40%), together with a method of injecting optically-pumped 3He (with 65% polarization). Pellets of these materials all have long polarization decay times (∼6 min for LiD at 2 K, ∼2 months for HD at 2 K, and ∼3 d for 3He at 77 K), all far greater than a plasma shot in a research tokamak such as DIII-D (∼20 s). Both species can be propelled from a single cryogenic injection gun. We review plasma requirements and strategies for detecting polarization survival. Polarization alters both fusion yields and the angular distribution of fusion products, and each of these provides a potential signal. In this paper we simulate a selection of shots with similar characteristics in a future high-Tion H plasma, and find ratios of yields from shots with fuel spins parallel and antiparallel reaching 1.3 (HD + 3He) to 1.6 (LiD + 3He) over a wide range of poloidal angles. (A companion paper finds sensitivity to fusion product angular distributions as reflected in the pitch angles of protons and alphas reaching the plasma facing wall.)