bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of L2 German on grammatical gender access in L1 Polish: proficiency matters
Authors: Długosz Kamil 
Published: June 2023

Abstract
Previous research has shown that bilinguals process nouns that have the same grammatical gender in their two languages faster than nouns that differ in gender between L1 and L2. This finding, referred to as the gender congruency effect, has so far only been documented in L2. Hence, the aim of the present study was to examine whether late unbalanced bilinguals would also show gender congruency effects in their L1. To that end, 44 L1 Polish/L2 German bilinguals were tested in a gender decision task in Polish, which included gender-congruent and gender-incongruent nouns. The results revealed a robust gender congruency effect in L1, which was limited to bilinguals with very high L2 proficiency. This indicates that bilinguals activate grammatical gender information in L2 when accessing gender in L1, providing that they are highly proficient in L2. More broadly, the study demonstrates that foreign language knowledge can affect native language performance in exclusively native contexts. Finally, as a first attempt to examine grammatical gender access in Polish, this study shows that feminine gender is accessed faster compared to masculine and neuter, suggesting that the ending -a is the most reliable gender cue in Polish.
Two phenomena behind the terminology of face
Authors: Lacroix René 
Published: June 2023

Abstract
In politeness research and other areas, scholars use a range of metaphorical expressions involving the term face, as in “lose face”, “threaten face” and “save face”, drawing upon Goffman’s paper “On face-work” (Goffman, Erving. 1967. Interaction ritual: Essays on face-to-face behavior. New York: Pantheon Books), often through Brown and Levinson’s influential theory of politeness (Brown, Penelope & Stephen C. Levinson. 1987. Politeness: Some universals in language usage. Cambridge: Cambridge University Press). The present paper argues that the interactional processes referred to by such expressions are of at least two kinds, here labeled “Observed-Behavior (OB) face-processes” and “Expressed-Attitude (EA) face-processes”. X’s OB face loss occurs when others negatively evaluate X on the basis of her behavior; X’s EA face loss occurs when others convey to X that they do not have the same values as her (“positive face”) or act in a way that impedes her freedom (“negative face”). Ten differences between OB and EA face-processes are set out. These differences are not acknowledged in the literature, which, as shown in this paper, leads to much ambiguity and confusion.
Chronic post-thoracotomy pain after lung cancer surgery: a prospective study of preoperative risk factors
Authors: Danielsen Allan Vestergaard , Andreasen Jan Jesper , Dinesen Birthe , Hansen John , Kjær-Staal Petersen Kristian , Simonsen Carsten , Arendt-Nielsen Lars 
Published: June 2023

Abstract

Objectives
The objective of this longitudinal cohort study was to investigate if preoperative pain mechanisms, anxiety, and depression increase risk of developing chronic post-thoracotomy pain (CPTP) after lung cancer surgery.

Methods
Patients with suspected or confirmed lung cancer undergoing surgery by either video-assisted thoracoscopic surgery or anterior thoracotomy were recruited consecutively. Preoperative assessments were conducted by: quantitative sensory testing (QST) (brush, pinprick, cuff pressure pain detection threshold, cuff pressure tolerance pain threshold, temporal summation and conditioned pain modulation), neuropathic pain symptom inventory (NPSI), and the Hospital Anxiety and Depression Scale (HADS). Clinical parameters in relation to surgery were also collected. Presence of CPTP was determined after six months and defined as pain of any intensity in relation to the operation area on a numeric rating scale form 0 (no pain) to 10 (worst pain imaginable).

Results
A total of 121 patients (60.2 %) completed follow-up and 56 patients (46.3 %) reported CPTP. Development of CPTP was associated with higher preoperative HADS score (p=0.025), higher preoperative NPSI score (p=0.009) and acute postoperative pain (p=0.042). No differences were observed in relation to preoperative QST assessment by cuff algometry and HADS anxiety and depression sub-scores.

Conclusions
High preoperative HADS score preoperative pain, acute postoperative pain intensity, and preoperative neuropathic symptoms were was associated with CPTP after lung cancer surgery. No differences in values of preoperative QST assessments were found. Preoperative assessment and identification of patients at higher risk of postoperative pain will offer opportunity for further exploration and development of preventive measures and individualised pain management depending on patient risk profile.
Antimicrobial Resistance in Non-typhoidal Salmonella from Retail Foods Collected in 2020 in China
Authors: Hu Yujie , Zhang Chenxi , Zhang Jing , Zhang Hongyuan , Xiao Yang , Dong Shuangjia , Song Yingyang , Dong Yinping , Bai Yao , Li Fengqin 
Published: June 2023

Objective:
Non-typhoidal Salmonella (NTS) is a major cause of human salmonellosis globally. Food animals are major NTS reservoirs. An increase in antimicrobial resistance (AMR) in foodborne NTS has led to clinical treatment failures. Here, to examine the prevalence and perform characterization of foodborne NTS with AMR in China, we tested the antimicrobial susceptibility of 1,256 NTS isolates cultured from retail foods in 2020 in China.

Methods:
The antimicrobial susceptibility of 26 antimicrobial agents representing 12 classes was evaluated with the broth-microdilution method; the presence of ten mcr genes was screened with multi-PCR. The complete closed genomes of mcr-gene-carrying isolates were generated by hybrid assembly through whole genome sequencing on both the PacBio and Illumina platforms. Genomic features and genetic environments of the mcr-1 gene were analysed.

Results:
The overall drug resistance rate was 92.28%, and the multi-drug resistance (MDR) rate was 76.53%. A total of 341 AMR profiles were determined, and resistance was highest to nalidixic acid (63.38%). Among 887 NTS isolates with MDR, 232 showed co-resistance to cefotaxime and ciprofloxacin, and 25 were resistant to ten classes of antimicrobial agents. The resistance of NTS isolated from different regions varied. Isolates from raw chicken sources most frequently showed resistance. Four NTS carried the mcr-1 gene and represented four different serotypes. Four mcr-1 gene-bearing plasmids from the four Salmonella isolates were classified into two replicon types (IncI2 and IncHI2A). Two mcr-1 genes in IncI2 type plasmids were found to be located between a PAP2 family protein-encoding gene and a relaxase-encoding gene, whereas the other two mcr-1 gene structures in IncHI2A type plasmids showed variations in the presence of insertion sequences.

Conclusion:
Our data demonstrated severe AMR among foodborne NTS isolated from food in China, thus highlighting the importance of antimicrobial susceptibility surveillance to decrease the spread of AMR, particularly to critical drugs in human medicine.
Spinal Sensorimotor Circuits Play a Prominent Role in Hindlimb Locomotor Recovery after Staggered Thoracic Lateral Hemisections but Cannot Restore Posture and Interlimb Coordination during Quadrupedal Locomotion in Adult Cats
Authors: Audet Johannie , Yassine Sirine , Lecomte Charly G. , Mari Stephen , Soucy Félix , Morency Caroline , Merlet Angèle N. , Harnie Jonathan , Beaulieu Claudie , Gendron Louis , Rybak Ilya A. , Prilutsky Boris I. , Frigon Alain 
Published: June 2023

AbstractSpinal sensorimotor circuits interact with supraspinal and peripheral inputs to generate quadrupedal locomotion. Ascending and descending spinal pathways ensure coordination between the forelimbs and hindlimbs. Spinal cord injury (SCI) disrupts these pathways. To investigate the control of interlimb coordination and hindlimb locomotor recovery, we performed two lateral thoracic hemisections on opposite sides of the cord (right T5–T6 and left T10–T11) at an interval of approximately two months in eight adult cats. In three cats, the spinal cord was transected at T12–T13. We collected electromyography (EMG) and kinematic data during quadrupedal and hindlimb-only locomotion before and after spinal lesions. We show that (1) cats spontaneously recover quadrupedal locomotion following staggered hemisections but require balance assistance after the second one, (2) coordination between the forelimbs and hindlimbs displays 2:1 patterns (two cycles of one forelimb within one hindlimb cycle) and becomes weaker and more variable after both hemisections, (3) left-right asymmetries in hindlimb stance and swing durations appear after the first hemisection and reverse after the second, and (4) support periods reorganize after staggered hemisections to favor support involving both forelimbs and diagonal limbs. Cats expressed hindlimb locomotion the day following spinal transection, indicating that lumbar sensorimotor circuits play a prominent role in hindlimb locomotor recovery after staggered hemisections. These results reflect a series of changes in spinal sensorimotor circuits that allow cats to maintain and recover some level of quadrupedal locomotor functionality with diminished motor commands from the brain and cervical cord, although the control of posture and interlimb coordination remains impaired.
Neonatal screening for primary and central congenital hypothyroidism: is it time to go Dutch?
Authors: Boelen Anita , Zwaveling-Soonawala Nitash , Heijboer Annemieke C , van Trotsenburg A S Paul 
Published: June 2023

Thyroid hormone (TH) is indispensable for brain development in utero and during the first 2–3 years of life, and the negative effects of TH deficiency on brain development are irreversible. Detection of TH deficiency early in life by neonatal screening allows early treatment, thereby preventing brain damage.
Inborn shortage of TH, also named congenital hypothyroidism (CH), can be the result of defective thyroid gland development or TH synthesis (primary or thyroidal CH (CH-T)). Primary CH is characterized by low blood TH and elevated thyroid-stimulating hormone (TSH) concentrations. Less frequently, CH is due to insufficient stimulation of the thyroid gland because of disturbed hypothalamic or pituitary function (central CH). Central CH is characterized by low TH concentrations, while TSH is normal, low or slightly elevated.
Most newborn screening (NBS) programs for CH are primarily TSH based and thereby do not detect central CH. Only a few NBS programs worldwide aim to detect both forms of CH by different strategies. In the Netherlands, we have a unique T4–TSH–thyroxine-binding globulin (TBG) NBS algorithm for CH, which enables the detection of primary and central CH.
Although the necessity of central CH detection by NBS is still under debate, it has been shown that most central CH patients have moderate-to-severe hypothyroidism instead of mild and that early detection of central CH by NBS probably improves its clinical outcome and clinical care for central CH patients with multiple pituitary hormone deficiency. We are therefore convinced that detection of central CH by NBS is of utmost importance.
Resemblances and differences between osteoradionecrosis of the jaw and medication-related osteonecrosis of the jaw
Authors: Golu Mihai Vlad , Paşcanu Ionela , Petrovan Cecilia , Mocan Simona , Cosarcă Adina , Bereczki Temistocle Despina , Ormenişan Alina 
Published: June 2023

Aim. The aim of this retrospective study was to identify the clinical, radiological, and histological characteristics of patients diagnosed with osteonecrosis of the jaw (ONJ) and treated at the Oral and Maxillo-Facial Surgery Clinic of the Emergency Clinical County Hospital of Targu Mures between 2017 and 2022. The study aimed to analyze correlations between patient characteristics, particularly their history of bone modifying agent use or local radiotherapy during cancer treatment, in order to identify specific patient profiles that could aid in evaluating treatment response and guide individualized treatment strategies.
Methods. Fifty-two patients diagnosed with ONJ were included in the study. The patients were divided into two groups based on their medical history: the bone modifying agent use group and the radiotherapy group. Clinical, radiological, and histological data were collected and analyzed. Statistical analysis, including p-values, was performed to compare patient characteristics between the two groups.
Results. Patients in the radiotherapy group were significantly older than those in the bone modifying agent use group (66 years vs. 56.9 years, p=0.001). There was a higher proportion of males in the radiotherapy group compared to the bone modifying agent use group (90% vs. 22%, p<0.001). Jaw involvement was more prevalent in the radiotherapy group compared to the bone modifying agent use group (95% vs. 66%, p=0.018). Histological analysis showed a similar frequency of Actinomyces species in both groups (50% vs. 34%, p=0.264).
Conclusions. The findings of this study suggest the existence of two distinct patient profiles based on their treatment history (bone modifying agent use vs. radiotherapy) in ONJ. Patients in the radiotherapy group were older, predominantly male, and exhibited a higher prevalence of jaw involvement. Histological analysis revealed no significant differences in Actinomyces species frequency between the two groups. These distinct patient profiles may indicate different responses to treatment, emphasizing the need for individualized treatment strategies tailored to specific patient characteristics. Further research is warranted to validate these findings and develop personalized approaches for managing ONJ.
Fathers, Breastfeeding, and Infant Sleep Practices: Findings From a State-Representative Survey
Authors: Parker John James , Simon Clarissa , Bendelow Anne , Bryan Michael , Smith Ruben A. , Kortsmit Katherine , Salvesen von Essen Beatriz , Williams Letitia , Dieke Ada , Warner Lee , Garfield Craig F. 
Published: June 2023

OBJECTIVES
To assess infant breastfeeding initiation and any breastfeeding at 8 weeks and safe sleep practices (back sleep position, approved sleep surface, and no soft objects or loose bedding [“soft bedding”]) by select paternal characteristics among a state-representative sample of fathers with new infants.

METHODS
Pregnancy Risk Assessment Monitoring System (PRAMS) for Dads, a novel population-based cross-sectional study, surveyed fathers in Georgia 2–6 months after their infant’s birth. Fathers were eligible if the infant's mother was sampled for maternal PRAMS from October 2018 to July 2019.

RESULTS
Of 250 respondents, 86.1% reported their infants ever breastfed and 63.4% reported breastfeeding at 8 weeks. Initiation and breastfeeding at 8 weeks were more likely to be reported by fathers who reported wanting their infant’s mother to breastfeed than those who did not want her to breastfeed or had no opinion (adjusted prevalence ratio [aPR] = 1.39; 95% confidence interval [CI], 1.15–1.68; aPR = 2.33; 95% CI, 1.59–3.42, respectively) and fathers who were college graduates than those with ≤high school diploma (aPR = 1.25; 95% CI, 1.06–1.46; aPR = 1.44; 95% CI, 1.08–1.91, respectively). Although about four-fifths (81.1%) of fathers reported usually placing their infants to sleep on their back, fewer fathers report avoiding soft bedding (44.1%) or using an approved sleep surface (31.9%). Non-Hispanic Black fathers were less likely to report back sleep position (aPR = 0.70; 95% CI, 0.54–0.90) and no soft bedding (aPR = 0.52; 95% CI, 0.30–0.89) than non-Hispanic white fathers.

CONCLUSIONS
Fathers reported suboptimal infant breastfeeding rates and safe sleep practices overall and by paternal characteristics, suggesting opportunities to include fathers in promotion of breastfeeding and infant safe sleep.
Development of method for the identification of hybrid challenges and threats in the national security management system
Authors: Shyshatskyi Andrii , Hurskyi Taras , Vdovytskyi Yevhenii , Vozniak Roman , Nalapko Oleksii , Andriishena Halyna , Shabanova-Kushnarenko Lyubov , Protas Nadiia , Vakulenko Yuliia , Pyvovarchuk Serhii 
Published: June 2023

As a result of Russian aggression against Ukraine, some fundamental theses regarding the nature of hybrid military operations will require clarification and even revision. First of all, this refers to the widespread perception of the asymmetric nature of hybrid threats as those used by a weaker opponent against a party with significantly greater military, technological and human potential. This, in turn, requires the use of modern and proven mathematical apparatus, which is capable of processing a large array of various types of data in a short period of time with a given reliability of making management decisions. The object of research is the system of strategic management of national security. The subject of the research is the method of detection and identification of hybrid challenges and threats in the national security management system. In the research, the method of detection and identification of hybrid challenges and threats in the national security management system was developed. The novelty of the research:
– a destructive effect on the system of national security management by adding an appropriate correction factor;
– the use of an improved procedure of deep learning of the database of the system of detection and identification of hybrid challenges and threats to the national security of the state;
– a mechanism for resolving conflicting cases of classification is used due to additional training, adaptation of detectors to the type and intensity of the hybrid challenge and threat to the national security of the state;
– the procedure for automatically calculating the detector activation threshold and the universality of the structure of their representation due to the hierarchy and flexibility for the available hardware resources of the detection and identification system.
It is advisable to implement the specified method in algorithmic and software while studying the state of the national security system.
Development of method for anti-icing materials consumption optimization during winter road maintenance
Authors: Kharchenko Anna , Smirnov Anatolii 
Published: June 2023

The object of research is the processes of managing the consumption of anti-icing materials during the winter maintenance of highways. The main hypothesis of the research is the application of mathematical modelling methods to optimize the consumption of anti-icing materials. The study considered the factors that affect the use of both individual types and anti-icing materials as a whole. It was determined that the temperature of the road surface and the selected winter maintenance strategy taking into account the level of service (LOS) are significant factors. A mathematical model of material consumption optimization based on the binary numbering system is proposed. Additional limitations to the model have been established: compliance with the criteria of reliability, preservation of assets, road safety, compliance with user expectations (social factor), environmental friendliness, efficiency of the use of materials. An algorithm for the application of the method of optimizing the consumption of anti-icing materials during the winter maintenance of highways has been developed. It was determined that the developed method solves the main problem of minimizing the costs of anti-icing materials, taking into account the requirements of the level of service, the chosen strategy, the temperature of the road surface and the criteria of impact on winter maintenance. It is proposed to implement the calculation according to this method using the built-in «Parameter selection» function in the Microsoft Excel license environment (USA). The results obtained by the optimization method, based on real data, showed the possibility of saving materials by about 23 %, which confirms the effectiveness of the proposed solutions.
The results of calculations based on the method of optimization of material consumption have practical value and can be used to make management decisions regarding the justification of winter road maintenance operations. The proposed method can be used both for the cost planning phase and in the case of analysis in the post-implementation period. This is an important aspect in the conditions of financial and resource uncertainty, including those related to circumstances of force majeure, in particular, martial law in Ukraine.
Association of single nucleotide polymorphisms of <i>TLR2</i>, <i>TLR4</i> and <i>TLR9</i> with atopic dermatitis
Authors: Svitich O. A. , Olisova O. Yu. , Meremianina E. A. , Rasskazova N. D. , Fomina V. A. , Potapova M. B. 
Published: June 2023

Toll-like receptors (TLRs) are the most studied among all Pattern Recognition Receptors, the main function of which is to initiate innate immune response by recognizing pathogen-associated molecular patterns of various microorganisms on the skin surface. TLR-mediated recognition plays an important role in linking innate and adaptive immunity that ultimately leads to the production of key cytokines, chemokines and antimicrobial peptides. Today, there is growing interest in research on single nucleotide polymorphisms (SNPs) in TLR genes and its influence on susceptibility to inflammatory disease, including atopic dermatitis. The aim of the research was to study the association of the rs5743708 gene polymorphism in the TLR2 gene, the rs4986791 gene polymorphism in the TLR4 gene and the rs352140 gene polymorphism in the TLR9 gene with the risk of developing severe cases of AD. A total of 100 patients with AD were included in the study (38 male and 62 female). The age range was from 18 to 65 years old. All participants were divided into 2 groups according to the SCORAD index (SCORing Atopic Dermatitis). The control group included 72 volunteers over 18 years old. The results of our study showed a statistically significant difference between the moderate AD group and healthy controls in the rs352140 gene polymorphism in the TLR9 gene (Figure 1). The frequency of the GG genotype of SNP rs352140 in TLR9 was 0.169 in the AD group versus 0.329 in the control group (p < 0.05; OR = 0.42; 95% CI = 0.18-0.97).In conclusion, the results of our study showed that the TLR9 rs352140 gene polymorphism may be linked to an increased risk of atopic dermatitis. Moreover, it was found that the GG genotype of SNP rs352140 in TLR9 can be used as a predictor of the risk of developing moderate AD.