bluuebunny/crossref_metadata_2025_split huggingface dataset:
Emergence of robotic technologies: implications for Nigerian academic libraries
Authors: Oladokun Bolaji David , Owolabi Abayomi Kehinde , Aboyade Modupe Aduke , Wiche Humphrey Igwechi , Aboyade Wahab Akanmu 
Published: March 2023

Purpose
Libraries may become obsolete in the 21st century unless they begin to harness new technology and improve information and service delivery. This paper aims to examine the emergence of robotic technologies with its implications to academic libraries in Nigeria.

Design/methodology/approach
The research, which was conducted on a desk, examined how the adoption of robotic technologies may affect library services and operations.

Findings
It is believed that robot adoption in libraries can enhance library services and give users with reliable information that can foster growth and development in the information age.

Originality/value
This paper is the original idea from the authors and does not reflect on any copyrighted materials. The paper recommended that academic libraries should collaborate with their parent institutions or organisations to create a strategy plan for cutting-edge technology, such as robots; federal and state governments should strengthen their alliances with robot vendors to take advantage of direct support; and open communication between library management boards and librarians should be encouraged, particularly when it comes to the acceptance and use of robots in libraries.
Sustainable supply chain of Indonesia’s textile & apparel industry: opportunities and challenges
Authors: Sarasi Vita , Primiana Ina , Harsanto Budi , Satyakti Yayan 
Published: March 2023

Purpose
As a leading sector that has entered the international market, the Indonesian Textile and Apparel (T&A) industry has begun to focus on sustainability issues; however, this study is still limited. This paper aims to conduct a systematic review and explore future research opportunities in developing sustainable supply chain management (SSCM) in the T&A industry in Indonesia, particularly in the small- and medium-sized enterprise (SME) sector.

Design/methodology/approach
A systematic literature review (SLR) through five academic databases, including Science Direct, IEEE Explore, Scopus, Google Scholar and Web of Science, was conducted and followed by a content analysis of the selected papers.

Findings
Directions for future research include designing a standardized and sustainable measurement of SSCM performance; analyzing SSCM practices in T&A SMEs through the concept of sustainable entrepreneurs; and exploring the application of a circular economy in the T&A industry, known as circular fashion, which is preferred by the community, affordable and environmentally friendly.

Research limitations/implications
This research only used secondary data. In-depth interviews with relevant experts should also be conducted to get a more comprehensive picture of this issue.

Originality/value
To the best of the author’s knowledge, this is the first SLR analyzing the implementation of SSCM in the T&A industry in Indonesia.
Preface: Listen to the voices of local beech forests: An ecological and evolutionary conception of beech under phylogenetic and environmental constraints
Authors: Kitamura Keiko , Hara Masatoshi , Tamaki Ichiro 
Published: March 2023

AbstractBeech has long been the subject of ecological research in many fields. Recent studies using new methods are now being conducted. This special feature focuses on local beech forests and offers a collection of articles to readers of Ecological Research.
Rethinking the Metre of Parzival: Iambic Verse for a Trochaic Language
Authors: Booth Joshua J. 
Published: March 2023

AbstractThe Middle High German (MHG) prosodic foot is uncontroversially considered to be trochaic, a fact which has traditionally led scholars to assume a preference for trochaic metre in poetry of the MHG Classical Period. However, given the trend elsewhere in mediaeval Europe (even in trochaic languages) to emulate French lyrics and compose verse in iambic metre, the uncritical assumption of a trochaic metre in all MHG poetry seems inadequate. A close examination of Parzival, an early thirteenth‐century grail romance by Wolfram von Eschenbach, suggests that the traditional analysis is not only insufficient but counter to the linguistic evidence. This paper argues for the first time that Parzival was in fact composed in iambic tetrameter, based on a close analysis of the rhythmic alternations within lines and the quantity and foot structure of line‐final syllables. Halle & Keyser's (1966) principles for iambic metre were used to produce a taxonomy of possible line structures in Parzival and the dominance of the wswswsws pattern, beginning on a weak beat and ending on a strong, offers convincing evidence in favour of iambic metre. The remaining lines can be neatly categorised as iambic by allowing feminine rhyme (with an extrametrical schwa syllable) or the construction of monosyllabic feet from a single heavy syllable. This analysis is further corroborated by the consistently iambic structure of line‐final feet, as well as the foot structures avoided by the poet, identified according to the weight of the final, penultimate and antepenultimate syllables. The present analysis has the advantage of explaining the various patterns of alternating prominence in the metre of Parzival much more consistently than the complex system advocated by the traditional literary view.
Reading smart: Queering and contextualising a cycling diary
Authors: Bachman‐Sanders Christine 
Published: March 2023

AbstractContradicting heteropatriarchal romance narratives in the historical archive, Bachman‐Sanders reads the diary of a woman cyclist from Leeds, UK written between 1893 and 1896 against the grain to reveal an identity for the diarist that is relationally and spatially constructed. She utilises feminist inter‐subjective reading practices and a queer interpretive framework to investigate the personal, genealogical, geographical and historical context surrounding this diary and to interrogate her own attachment to the research subject. Bachman‐Sanders produces a collection of images and maps that explore the intimate connections and non‐linearity of bicycle tourism and feminist historical research, pushing the limits of the ‘queer object’.
Sauchinone inhibits breast cancer cell proliferation through regulating microRNA‐148a‐3p/HER‐2 axis
Authors: Hu Xiaolei , Wang Jie , Shang Pei , Wang Shan , Chen Lujia , Ye Changsheng , Yao Guangyu 
Published: March 2023

AbstractBackgroundSauchinone is extracted from the root of Saururus chinensis and exhibits potent antitumor effects in various human cancers. However, how sauchinone is involved in breast cancer has not been well studied.MethodsCells apoptosis, cell proliferation, and cycle distribution were evaluated. Xenograft tumor mouse model was constructed to investigate the roles of sauchinone. The relevant protein expression was detected by western blot.ResultsWe found that sauchinone significantly reduced proliferation and survival, also induced apoptosis of MCF‐7 and Bcap‐37 cells in vitro. Sauchinone significantly increased miR‐148a‐3p expression, and human epidermal growth factor receptor (HER)‐2 targeted on miR‐148a‐3p. Sauchinone exposure downregulated HER‐2 expression whose overexpression partly eliminated the inhibitory effect of sauchinone. Further, sauchinone efficiently inhibited breast cancer progression through downregulating HER‐2 expression in vivo.ConclusionOur results indicate that sauchinone efficiently inhibits breast cancer progression through regulating miR‐148a‐3p/HER‐2 axis, suggesting that sauchinone could be an effective anticancer agent for breast cancer.
Efficacy of different irrigant activation devices in removing dentin debris from an artificial isthmus connecting curved canals
Authors: Plotino Gianluca , Özyürek Taha , Gündoğar Mustafa , Uslu Gülşah , Pedullà Eugenio , Careddu Roberto , Franco Vittorio 
Published: March 2023

AbstractThe aim of this study was to evaluate the debridement efficacy of sonic irrigation (EDDY; VDW, Munich, Germany and EndoActivator; Dentsply‐Sirona, Ballaigues, Switzerland) and ultrasonically activated irrigation (Irrısafe; Satelec Acteon, Merignac, France) in a simulated canal isthmus connecting curved canals. Transparent resin blocks were produced containing two curved canals connected with an isthmus. The isthmus was then filled with dentin debris. Three irrigant activation cycles were performed and the amount of remaining debris was compared analysing pictures taken after each activation cycle. Data were statistically analysed using one‐way ANOVA and post hoc Tukey tests at a significance level of p < 0.05. EDDY showed greater efficiency in removing dentin debris from the simulated isthmus than the other techniques tested. An increase in the activation time enhanced the efficiency of both EDDY and ultrasonically activated irrigation in debris removal.
Opioid use disorder in the active service: Implications for intervention
Authors: Moore Brian A. , Vincent Sophie R. , Schlenk Michael A. , McNamara Corinne L. 
Published: March 2023

AbstractBackground and ObjectivesMilitary service members experience occupational‐specific injuries that may result in chronic pain and comorbid behavioral health concerns.MethodsData from the Defense Medical Epidemiology Database was used to examine opioid use disorder (OUD) diagnoses between 2016 and 2021. Statistical analysis calculated incidence rates and diagnostic variability by demographic density.ResultsThe average incidence rate of OUD was 6.1 (per 10,000) and declined by 34% between 2016 and 2021. Diagnoses were most frequently made in service members classified as male, married, white, aged 30–39, junior enlisted, and serving in the Army.Conclusions and Scientific SignificanceTo our knowledge, this is the first study to examine the incidence rates of OUD among active duty personnel.
Impact of age on outcomes in young women with breast cancer
Authors: Yadav Budhi S. , Bansal Anshuma , Das Deepak , Thakur Pragyat , Gupta Ankita , Dahiya Divya 
Published: March 2023

AbstractBackgroundIn this study, we compared outcomes in young and very young patients with breast cancer (BC).Materials and methodsBetween January 1990 to December 2010, 414 young women (age ≤35 years) with BC were registered in the radiotherapy (RT) outpatient department. Patients were divided into young (31–35 years) and very young (18–30 years). They were compared for clinical, pathological characteristics, and treatment‐related factors such as RT and systemic therapy. Outcomes compared between the two groups were locoregional recurrence rate (LRR), local recurrence‐free survival (LRFS), disease‐free survival (DFS), overall survival (OS), and toxicities. LRFS, DFS, and OS were estimated using the Kaplan‐Meier method.ResultsOut of 414 patients, 138 and 276 were very young and young, respectively. Clinical, pathological, and treatment characteristics were balanced between the two groups except for more patients in the young group who had pN3 disease and received hormonal therapy; 41 (15%) versus seven (5%) and 171 (62%) versus 62 (45%) in the very young group, respectively. Median follow‐up was 84 months (range 12–363 months). LR was seen in 16 (11.6%) and 25 (9%) patients in the very young and young groups, respectively (p = 0.28). The hazard ratios for LR, disease recurrence, and death in the very young group relative to the young group were 1.11 (p = 0.25), 1.0 (p = 1.0), and 1.05 (p = 0.79), respectively. Estimated 10‐year LRFS, DFS and OS were 80% versus 86%, 63% versus 61%, and 66% versus 64% in the very young and young groups, respectively. Lymphedema, cardiac toxicity, and second malignancy developed in seven (5%) versus 23 (8%), one (1%) versus three (1%), and seven (5%) versus 18 (7%) patients in the very young and young groups, respectively.ConclusionIn very young and young patients with BC, there was no significant difference in LRR, LRFS, DFS, or OS. Toxicities were also comparable between the two groups.
Measuring the quality of skin cancer management in primary care: A scoping review
Authors: Spanos Samantha , Singh Nehal , Laginha Bela I. , Arnolda Gaston , Wilkinson David , Smith Andrea L. , Cust Anne E. , Braithwaite Jeffrey , Rapport Frances 
Published: March 2023

AbstractSkin cancer is a growing global problem and a significant health and economic burden. Despite the practical necessity for skin cancer to be managed in primary care settings, little is known about how quality of care is or should be measured in this setting. This scoping review aimed to capture the breadth and range of contemporary evidence related to the measurement of quality in skin cancer management in primary care settings. Six databases were searched for relevant texts reporting on quality measurement in primary care skin cancer management. Data from 46 texts published since 2011 were extracted, and quality measures were catalogued according to the three domains of the Donabedian model of healthcare quality (structure, process and outcome). Quality measures within each domain were inductively analysed into 13 key emergent groups. These represented what were deemed to be the most relevant components of skin cancer management as related to structure, process or outcomes measurement. Four groups related to the structural elements of care provision (e.g. diagnostic tools and equipment), five related to the process of care delivery (e.g. diagnostic processes) and four related to the outcomes of care (e.g. poor treatment outcomes). A broad range of quality measures have been documented, based predominantly on articles using retrospective cohort designs; systematic reviews and randomised controlled trials were limited.
Open educational resources: Evaluation of students' intention to use and motivation to create
Authors: Adedoyin Olasile Babatunde , Altinay Fahriye 
Published: March 2023

AbstractThe advent of open educational resources (OER) has increased access to pedagogical resources that promote the quality of education, but the potential of the OER to transform pedagogical practices is yet to be realized, mainly as a result of a lack of concentration on the policies and practices necessary to support the idea of openness within the academic institutions. Several exploratory attentions have been given to educators’ adoption of OER, but little or none exists on university students’ intention to use and motivation to create OER. This study explores university students’ intention to use OER in Study 1 and motivation to create OER in Study 2 using a non‐experimental research design with a survey method and partial least squares structural equation modelling (PLS‐SEM) for the two studies. The findings indicated that the relationship between perceived ease of use, perceived usefulness, zero price accessibility and availability, and attitude and university students’ intention to use OER is significantly positive for Study 1. This showed that university students’ intention to use OER can be influenced by these factors. The relationship between competence and mastery of content, personal development, reward system and motivation to create OER is significantly positive for Study 2. This implies that university students are not mere users of OER but partners in the OER crusade as creators.
Practitioner notesWhat is already known about this topic

Significant roles of OER.
Faculty members as OER developers.
Students as mere users of OER.
What this paper adds

Factors that influence university students’ intentions to use OER using a blended TAM model.
Factors that influence university students’ motivation to create OER using a blended SDT theory.
The significant roles of university students as OER developers.
Implications for practice and/or policy

University students are not mere users of OER but partners in the OER crusade as creators.
Extensive information on the factors to focus on by faculty members to improve university students’ intentions to use and motivation to create OER.
The need for OER policymakers to concentrate on the factors highlighted in this study to make OER policies that will promote university students’ motivation to create OER.
GBT021601 improves red blood cell health and the pathophysiology of sickle cell disease in a murine model
Authors: Dufu Kobina , Alt Carsten , Strutt Steven , Partridge James , Tang Tzechiang , Siu Vincent , Liao‐Zou Hilary , Rademacher Peter , Williams Alexander T. , Muller Cynthia R. , Geng Xin , Pochron Mira Patel , Dang Annie Nguyen , Cabrales Pedro , Li Zhe , Oksenberg Donna , Cathers Brian E. 
Published: March 2023

SummaryThe pathophysiologic mechanism of sickle cell disease (SCD) involves polymerization of deoxygenated haemoglobin S (HbS), leading to red blood cell (RBC) sickling, decreased RBC deformability, microvascular obstruction, haemolysis, anaemia and downstream clinical complications. Pharmacological increase in the concentration of oxygenated HbS in RBCs has been shown to be a novel approach to inhibit HbS polymerization and reduce RBC sickling and haemolysis. We report that GBT021601, a small molecule that increases HbS‐oxygen affinity, inhibits HbS polymerization and prevents RBC sickling in blood from patients with SCD. Moreover, in a murine model of SCD (SS mice), GBT021601 reduces RBC sickling, improves RBC deformability, prolongs RBC half‐life and restores haemoglobin levels to the normal range, while improving oxygen delivery and increasing tolerance to severe hypoxia. Notably, oral dosing of GBT021601 in animals results in higher levels of Hb occupancy than voxelotor and suggests the feasibility of once‐daily dosing in humans. In summary, GBT021601 improves RBC health and normalizes haemoglobin in SS mice, suggesting that it may be useful for the treatment of SCD. These data are being used as a foundation for clinical research and development of GBT021601.
PR‐DUB safeguards Polycomb repression through H2AK119ub1 restriction
Authors: Li Rui , Huang Dandan , Zhao Yingying , Yuan Ye , Sun Xiaoyu , Dai Zhongye , Huo Dawei , Liu Xiaozhi , Helin Kristian , Li Mulin Jun , Wu Xudong 
Published: March 2023

AbstractPolycomb group (PcG) proteins are critical chromatin regulators for cell fate control. The mono‐ubiquitylation on histone H2AK119 (H2AK119ub1) is one of the well‐recognized mechanisms for Polycomb repressive complex 1 (PRC1)‐mediated transcription repression. Unexpectedly, the specific H2AK119 deubiquitylation complex composed by additional sex comb‐like proteins and BAP1 has also been genetically characterized as Polycomb repressive deubiquitnase (PR‐DUB) for unclear reasons. However, it remains a mystery whether and how PR‐DUB deficiency affects chromatin states and cell fates through impaired PcG silencing. Here through a careful epigenomic analysis, we demonstrate that a bulk of H2AK119ub1 is diffusely distributed away from promoter regions and their enrichment is positively correlated with PRC1 occupancy. Upon deletion of Asxl2 in mouse embryonic stem cells (ESCs), a pervasive gain of H2AK119ub1 is coincident with increased PRC1 sampling at chromatin. Accordingly, PRC1 is significantly lost from a subset of highly occupied promoters, leading to impaired silencing of associated genes before and after lineage differentiation of Asxl2‐null ESCs. Therefore, our study highlights the importance of genome‐wide H2AK119ub1 restriction by PR‐DUB in safeguarding robust PRC1 deposition and its roles in developmental regulation.
The usefulness of nuclear area in the diagnosis of high‐grade urothelial carcinoma cells in voided urine cytology
Authors: Sakumo Kazuma , Morihashi Kenta , Nakamura Akihiro , Nukaya Takuhisa , Sumitomo Makoto , Nakamura Muneo , Sofue Tadashi , Haba Reiji , Itoh Tomoo , Kamoshida Shingo , Ohsaki Hiroyuki 
Published: March 2023

AbstractObjectiveThe Paris System for Reporting Urinary Cytology considered the nuclear‐to‐cytoplasmic (N:C) ratio as the most important cytomorphological feature for detecting high‐grade urothelial carcinoma (HGUC) cells. Few quantitative studies have been conducted on other features although quantitative studies on the N:C ratio have been reported. Therefore, this study quantitatively analysed important cytomorphological features in distinguishing benign reactive cells from HGUC cells.MethodsWe analysed 2866 cells from the urine of 52 patients. A digital image analyser was used to quantitatively measure the nuclear area, cell area, N:C ratio, and nuclear roundness for HGUC cells and benign reactive cells. Additionally, the diagnostic value of quantitative cytomorphological criteria in HGUC cells was evaluated by the receiver operating characteristic curve.ResultsThe area under the curve for the prediction of HGUC cells for all cells and the top five cells was in the following order: nuclear area (0.920 and 0.992, respectively), N:C ratio (0.849 and 0.977), cell area (0.781 and 0.920), and nuclear roundness (0.624 and 0.605). The best cutoff value of the N:C ratio to differentiate HGUC cells from benign reactive cells was 0.438, and using the N:C ratio of 0.702, the positive predictive value obtained was 100%.ConclusionsOur study indicated that nuclear area is a more important cytomorphological criterion than the N:C ratio for HGUC cell detection. Moreover, extracted data of the top five cells were more valuable than the data of all cells, which can be helpful in the routine practice and future criteria definition in urine cytology.
Meta‐analysis shows forest soil CO2 effluxes are dependent on the disturbance regime and biome type
Authors: Akande Oluwabunmi J. , Ma Zilong , Huang Chenyan , He Fangliang , Chang Scott X. 
Published: March 2023

AbstractForest soil CO2 efflux (FCO2) is a crucial process in global carbon cycling; however, how FCO2 responds to disturbance regimes in different forest biomes is poorly understood. We quantified the effects of disturbance regimes on FCO2 across boreal, temperate, tropical and Mediterranean forests based on 1240 observations from 380 studies. Globally, climatic perturbations such as elevated CO2 concentration, warming and increased precipitation increase FCO2 by 13% to 25%. FCO2 is increased by forest conversion to grassland and elevated carbon input by forest management practices but reduced by decreased carbon input, fire and acid rain. Disturbance also changes soil temperature and water content, which in turn affect the direction and magnitude of disturbance influences on FCO2. FCO2 is disturbance‐ and biome‐type dependent and such effects should be incorporated into earth system models to improve the projection of the feedback between the terrestrial C cycle and climate change.