bluuebunny/crossref_metadata_2025_split huggingface dataset:
Short‐term effect of the prone masturbation training on premature ejaculation
Authors: Ma Gongchao , Wang Chunlin , Chen Xiaohong , Xi Yu , Lai Yufen , Zhang Yan 
Published: June 2023

AbstractBackgroundWhether conventional behavioral therapies for premature ejaculation can significantly improve the intravaginal ejaculatory latency time is still controversial. Prone masturbation is rare and observed in some patients with delayed ejaculation. Therefore, we tried to verify whether the regular prone masturbation training method had a therapeutic effect on premature ejaculation.MethodsFrom July to December 2018, a total of 21 patients met the enrollment criteria and volunteered to participate. Participants were diagnosed with premature ejaculation with an intravaginal ejaculatory latency time of less than 3 min and a Premature Ejaculation Diagnostic Tool score greater than 9. Participants performed 12‐week prone masturbation training.ResultsTen patients completed the entire treatment regimen. The mean age of the 10 participants was 30.4 ± 6.1 years, the mean frequency of sexual intercourse was 1.9 ± 0.83 times a week, and the median duration of premature ejaculation was 1.5 years. After 3 months of prone masturbation training, the median self‐reported intravaginal ejaculatory latency time significantly increased from 60 to 105 s (p = 0.011), and the mean Premature Ejaculation Diagnostic Tool scores decreased from 15.0 ± 3.7 to 12.7 ± 3.7 points (p = 0.119).ConclusionsThe regular prone masturbation training method, as a novel behavioral therapy, probably has a therapeutic effect on premature ejaculation.
Penile mass formation after neglected penile fracture: Surgical management with pericardial graft reinforcement
Authors: Thompson Laura , Khalafalla Kareim , Wang Run 
Published: June 2023

AbstractBackgroundPenile fracture is defined as the rupture of the tunica albuginea of the corpora cavernosa while in an erect state, during mostly intercourse or masturbation. Diagnosis of such condition is mainly clinical, while on the other hand, seeking medical attention is often delayed, and treatment options depend upon the time of presentation.MethodsThis case report details a patient who developed a penile cystic fibro‐hematoma lesion, 2 months after a neglected penile fracture. After proper assessment including detailed history, physical exam and a penile doppler ultrasound, patient was elected for surgery.ResultsThe patient underwent surgical removal of the mass, correction of the curvature, and reinforcement of the weakened tunica albuginea with a pericardium graft. Postoperative course was uneventful. At follow‐up, he reported normal erectile function with resolved penile curvature.ConclusionThis highlights the importance of seeking prompt medical attention for suspected penile fractures to avoid potential long‐term complications.
Providing power reserve for secondary grid frequency regulation of offshore wind farms through yaw control
Authors: Oudich Younes , Gyselinck Johan , De Belie Frederik , Kinnaert Michel 
Published: June 2023

AbstractThe ability to significantly contribute to the frequency regulation and provide valuable ancillary services to the transmission system operator (TSO) is one of the present wind farm (WF) challenges, due to the limitations of wind speed forecasting and insufficient power reserve in certain operating conditions notably. In this work, the feasibility of WFs to participate in frequency restoration reserve (FRR) through yaw control is assessed. To this end, a distributed yaw optimization method is developed to evaluate the power gain achieved by yaw redirection based on wind turbine cooperation and compared with a greedy approach. The method relies on a static wake model whose parameters are estimated in a systematic way from simulation data generated with FAST.Farm. Through a case study based on a scaled version of the Belgian Mermaid offshore WF, it is demonstrated that the requirements of the TSO are fulfilled both in terms of response time and level of power reserve for most wind directions. The assessment is limited to wind speeds below the rated speed of the considered wind turbines.
Digital forensics challenges and readiness for 6G Internet of Things (IoT) networks
Authors: Akinbi Alex Olushola 
Published: June 2023

AbstractThe development of sixth‐generation (6G) wireless communication technology is expected to provide super high‐speed data transmission, and advanced network performance than the current fifth‐generation (5G) and be fully functional by the 2030s. This development will have a significant impact and add improvements to digital extended reality (XR), autonomous systems, vehicular ad hoc networks (VANETs), artificial intelligence (AI), underwater communications, blockchain technology, pervasive biomedical informatics and smart cities built on the digital infrastructure backbone of the Internet of Things (IoT). The ubiquitous nature of this large‐scale 6G‐enabled IoT that offers faster connectivity capabilities and integrates both terrestrial and non‐terrestrial networks will not only create new data security and privacy issues but also provide a treasure trove of digital evidence useful for digital forensic examiners investigating security incidents and cybercrime. However, for digital forensic examiners, evidence collection, preservation and analysis will become a priority in the successful deployment of 6G IoT networks. In this study, we define key applications of 6G network technology to the Internet of Things and its existing architectures. The survey introduces potential digital forensic challenges and related issues affecting digital forensic investigations specific to 6G IoT networks. Finally, we highlight and discuss forensic readiness and future research directions for identified challenges within the 6G IoT network environments.This article is categorized under:
Digital and Multimedia Science > IoT Forensics
Equivalences between 2D dilaton gravities, their asymptotic symmetries, and their holographic duals
Authors: Ecker Florian , Grumiller Daniel , Valcárcel Carlos , Vassilevich Dmitri 
Published: June 2023

Abstract
Dilaton gravities in two dimensions can be formulated as particular Poisson sigma models. Target space diffeomorphisms map different models to each other and establish a one-to-one correspondence between their classical solutions. We obtain a general form of such diffeomorphisms in Lorentzian and Euclidean signatures and use them to extend known holographic results, including the Schwarzian action on the asymptotic boundary, from JT to a large class of dilaton gravity models.
Wilson loops and defect RG flows in ABJM
Authors: Castiglioni Luigi , Penati Silvia , Tenser Marcia , Trancanelli Diego 
Published: June 2023

Abstract
We continue our study of renormalization group (RG) flows on Wilson loop defects in ABJM theory, which we have initiated in arXiv:2211.16501. We generalize that analysis by including non-supersymmetric fixed points and RG trajectories. To this end, we first determine the “ordinary”, non-supersymmetric Wilson loops, which turn out to be two and to include an R-symmetry preserving coupling to the scalar fields of the theory, contrary to their four-dimensional counterpart defined solely in terms of the gauge field holonomy. We then deform these operators by turning on bosonic and/or fermionic couplings, which trigger an elaborate, multi-dimensional network of possible RG trajectories connecting a large spectrum of fixed points classified in terms of the amount (possibly zero) of supersymmetry and R-symmetry preserved. The β-functions are computed to leading order in the ABJM coupling but exactly in the deformation parameters, using an auxiliary one-dimensional theory on the defect and a dimensional regularization scheme. A striking result is the different behavior of the two ordinary Wilson loops, of which one turns out to be a UV unstable point while the other is IR stable. The same is true for the two 1/2 BPS Wilson loops. We interpret our results from a defect CFT (dCFT) point of view, computing the anomalous dimensions of the operators associated to the deformations and establishing appropriate g-theorems. In particular, the fermionic unstable fixed point is associated to a dCFT which is not reflection positive.
Additively manufactured cure tools for composites manufacture
Authors: Valentine Max D. A. , Radhakrishnan Arjun , Maes Vincent K. , Pegg Elise C. , Valero Maria D. R. , Kratz James , Dhokia Vimal 
Published: June 2023

AbstractThis research presents a novel framework for the design of additively manufactured (AM) composite tooling for the manufacture of carbon fibre-reinforced plastic composites. Through the rigorous design and manufacture of 30 unique AM tools, the viability of a design for AM framework was evaluated through measuring the performance with respect to geometrical accuracy and thermal responsiveness, and simulating the tool specific stiffness. The AM components consisted of a thin layup facesheet, stiffened by a low density lattice geometry. These tools were successfully used to layup and cure small composite components. The tooling was highly thermally responsive, reaching above 93% of the applied oven heating rate and up to 17% faster heating rates compared to similar mass monolithic tools. The results indicate that thermal overshoot has a greater dependence on the lattice density while the heating rate was more sensitive to the facesheet thickness. Lattice densities of as little as 5% were manufactured and the best overall geometry was a graded gyroid lattice with thicker walls near the surface and thinner walls at the base, attached to a 0.7 mm thick facesheet. The outputs from this research can provide a new route to the design and manufacture of mould tools, which could have significant impacts in the composites sector with new, lighter, more energy efficient tooling.
Investigation of die designs on welding quality and billet material utilisation for multi-container extrusion of wide stiffened aluminium panels
Authors: Zhang Zhe , Zhou Wenbin , Shi Zhusheng , Lin Jianguo 
Published: June 2023

AbstractWide stiffened aluminium panels are extensively used in aerospace, marine, and civil industries due to their light-weight structure and high stiffness. In this paper, a wide stiffened aluminium panel was manufactured using the principle of the multi-container extrusion, and a comparative study was conducted using two different die designs at the same extrusion condition, in which metal flow behaviour, extrusion force, welding quality, and billet material utilisation have been investigated numerically. Additionally, the effect of extrusion speed on the extrusion process was evaluated with the modified design. It was shown that, compared with the initial design, better metal flow behaviour can be obtained in the modified design. Multi-container extrusion greatly reduces the extrusion force, and the modified design results in a more uniform extrusion force for each extrusion container. The total extrusion force for the modified design is slightly higher compared with the initial die design, due to the increased friction in the upper die channels and the second-step welding chamber. Besides, the modified design of the multi-container extrusion can obtain better welding quality evaluated by different welding criteria, and the extrusion speed has a minor effect on the welding quality. The most notable feature is that the modified design greatly improves the material utilisation, which could save 39.5% material compared to the initial design.
Winter, spring, summer or fall: temporal patterns in placenta-mediated pregnancy complications—an exploratory analysis
Authors: Jeppegaard Maria , Rasmussen Steen C. , Anhøj Jacob , Krebs Lone 
Published: June 2023

Abstract
Purpose
Placenta-mediated pregnancy complications, like growth restriction and hypertensive disorders, are leading causes of maternal, fetal and neonatal morbidity and mortality in high-income countries. The purpose was to investigate if there is a seasonal variation in placenta-mediated pregnancy complications (small for gestational age, intrauterine growth restriction, preeclampsia, preterm birth and intrauterine fetal death).

Methods
This is a Danish cohort study including all singleton deliveries at gestational week 22 up to and including week 41 conceived from December 2006 to November 2016 (N = 555,459). We used statistical process control charts to visualize data and to test for patterns of non-random variation in data over time for pregnancies with risk factors (BMI, diabetes, in vitro fertilization, maternal age > 40 years, primipara, previous caesarean and smoking) and each of the following outcome: fetal growth restriction, hypertensive disorders, preterm birth and intrauterine fetal death. The study was approved by the Danish Data Protection agency; REG-039-2019.

Results
We found a seasonal pattern in hypertensive disorders during pregnancy with dips in pregnancies conceived in the fall season and highest risk by conception in the spring and summer season. We found no apparent seasonality in cases of preterm delivery, small for gestational age and intrauterine mortality. Individual risk factors (e.g. smoking and obesity) for placenta-mediated complicated over time were in consistency with the general trends.

Conclusions
We found a significant seasonal variation in the risk of hypertensive disorders of pregnancy with highest risk by conception in the spring and summer season. This study found no seasonal variation in other placenta-mediated complications.
A model of privately funded public research
Authors: Greve Thomas , Keiding Hans 
Published: June 2023

AbstractWe present a simple model of research, in which it is possible to compare the cost of private versus public research activity. The principal aim is to find conditions under which private firms might decide to provide funding, partially or fully, for research carried out by public research organizations. Since the underlying research problem is given, differences in cost depend mainly on the contracts between the firm or the public organization on one side and the researchers employed in the project on the other, together with the incentives which are implied by these contracts. We find that under suitable assumptions it is advantageous for the private firm to outsource its research to a public organization. The free access for the general public to research results obtained by public research organizations may however be an obstacle to outsourcing, unless some public funding is forthcoming.
The impact of passive alveolar molding vs. nasoalveolar molding on cleft width and other parameters of maxillary growth in unilateral cleft lip palate
Authors: Parhofer Robert , Rau Andrea , Strobel Karin , Gölz Lina , Stark Renée , Ritschl Lucas M. , Wolff Klaus-Dietrich , Kesting Marco R. , Grill Florian D. , Seidel Corinna L. 
Published: June 2023

Abstract

Objective

Passive alveolar molding (PAM) and nasoalveolar molding (NAM) are established presurgical infant orthodontic (PSIO) therapies for cleft lip palate (CLP) patients. PAM guides maxillary growth with a modified Hotz appliance, while NAM also uses extraoral taping and includes nasal stents. The effects of these techniques on alveolar arch growth have rarely been compared.

Material and methods
We retrospectively compared 3D-scanned maxillary models obtained before and after PSIO from infants with unilateral, non-syndromic CLP treated with PAM (n = 16) versus NAM (n = 13). Nine anatomical points were set digitally by four raters and transversal/sagittal distances and rotations of the maxilla were measured.

Results
Both appliances reduced the anterior cleft, but NAM percentage wise more. NAM decreased the anterior and medial transversal width compared to PAM, which led to no change. With both appliances, the posterior width increased. The alveolar arch length of the great and small segments and the sagittal length of the maxilla increased with PAM but only partially with NAM. However, NAM induced a significant greater medial rotation of the larger and smaller segment compared to PAM with respect to the lateral angle.

Conclusions
NAM and PAM presented some significant differences regarding maxillary growth. While NAM reduced the anterior cleft and effectively rotated the segments medially, PAM allowed more transversal and sagittal growth.

Clinical relevance
The results of this study should be taken into consideration when to decide whether to use PAM or NAM, since they show a different outcome within the first few months. Further studies are necessary regarding long-term differences.
Assessing of the Italian version of the Memory Strategy Test (TMS) in people with Parkinson disease: a preliminary descriptive psychometric study
Authors: Vaccaro Maria Grazia , Pullano Luca , Canino Silvia , Pastore Massimiliano , Sarica Alessia , Quattrone Andrea , Fernandes Sara Margarida , Migliorini Filippo , Maestu Fernando , Quattrone Aldo 
Published: June 2023

Abstract
Background

Previous literature has shown that executive functions (EF) are related to performance in memory (M) tasks. The Test of Memory strategies (TMS) is a psychometric test that examines EF and M simultaneously and it was recently validated on an Italian healthy cohort. The first aim of the study was to apply TMS, for the first time, on a sample of patients with Parkinson's disease (PD), who are characterized by mild cognitive impairment. The second aim is to investigate whether TMS scores can discriminate PD patients from healthy controls.

Method
Ninety-eight subjects were enrolled, including 68 patients with PD, and 30 Italian healthy controls (HC), who also underwent a memory evaluation through well-known tests.

Results
Confirmatory factor analysis (CFA) demonstrated that TMS of PD patients had a bi-dimensional structure as previously found in healthy cohort. In detail, The TMS-1 and TMS-2 lists require greater involvement of the EF factor, while TMS-3, TMS-4 and TMS-5 the M factor. Receiver operating characteristic (ROC) curves and precision-recall (PR) curves showed that the M subscale can distinguish between HC and PD, while EF had poor discrimination power.

Conclusion
The hypothesized prediction model of TMS test seems to have adequate ability to discriminate PD from HC especially for the M function.
Heterologous Expression and Biochemical Characterization of a New Chloroperoxidase Isolated from the Deep-Sea Hydrothermal Vent Black Yeast Hortaea werneckii UBOCC-A-208029
Authors: Cochereau Bastien , Le Strat Yoran , Ji Qiaolin , Pawtowski Audrey , Delage Ludovic , Weill Amélie , Mazéas Lisa , Hervé Cécile , Burgaud Gaëtan , Gunde-Cimerman Nina , Pouchus Yves François , Demont-Caulet Nathalie , Roullier Catherine , Meslet-Cladiere Laurence 
Published: June 2023

Abstract
The initiation of this study relies on a targeted genome-mining approach to highlight the presence of a putative vanadium-dependent haloperoxidase-encoding gene in the deep-sea hydrothermal vent fungus Hortaea werneckii UBOCC-A-208029. To date, only three fungal vanadium-dependent haloperoxidases have been described, one from the terrestrial species Curvularia inaequalis, one from the fungal plant pathogen Botrytis cinerea, and one from a marine derived isolate identified as Alternaria didymospora. In this study, we describe a new vanadium chloroperoxidase from the black yeast H. werneckii, successfully cloned and overexpressed in a bacterial host, which possesses higher affinity for bromide (Km = 26 µM) than chloride (Km = 237 mM). The enzyme was biochemically characterized, and we have evaluated its potential for biocatalysis by determining its stability and tolerance in organic solvents. We also describe its potential three-dimensional structure by building a model using the AlphaFold 2 artificial intelligence tool. This model shows some conservation of the 3D structure of the active site compared to the vanadium chloroperoxidase from C. inaequalis but it also highlights some differences in the active site entrance and the volume of the active site pocket, underlining its originality.
The link between physician motivation and care
Authors: Oxholm Anne Sophie , Gyrd-Hansen Dorte , Jacobsen Christian Bøtcher , Jensen Ulrich Thy , Pedersen Line Bjørnskov 
Published: June 2023

AbstractStudies report an unexplained variation in physicians’ care. This variation may to some extent be explained by differences in their work motivation. However, empirical evidence on the link between physician motivation and care is scarce. We estimate the associations between different types of work motivation and care. Motivation is measured using validated questions from a nation-wide survey of Danish general practices and linked to high-quality register data on their care in 2019. Using a series of regression models, we find that more financially motivated practices generate more fee-for-services per patient, whereas practices characterised by greater altruistic motivation towards the patient serve a larger share of high-need patients and issue more prescriptions for antibiotics per patient. Practices with higher altruism towards society generate lower medication costs per patient and prescribe a higher rate of narrow-spectrum penicillin, thereby reducing the risk of antimicrobial resistance in the population. Together, our results suggest that practices’ motivation is associated with several dimensions of healthcare, and that both their financial motivation and altruism towards patients and society play a role. Policymakers should, therefore, consider targeting all provider motivations when introducing organisational changes and incentive schemes; for example, by paying physicians to adhere to clinical guidelines, while at the same time clearly communicating the guidelines’ value from both a patient and societal perspective.
Inertial instability and phase error in Euler forward predictor-corrector time integration schemes: Improvement of modeling Great Lakes thermal structure and circulation using FVCOM
Authors: Wang Jia , Fujisaki-Manome Ayumi , Kessler James , Cannon David , Chu Philip 
Published: June 2023

AbstractThis study investigates the inertial stability properties and phase error of numerical time integration schemes in several widely-used ocean and atmospheric models. These schemes include the most widely used centered differencing (i.e., leapfrog scheme or the 3-time step scheme at n-1, n, n+1) and 2-time step (n, n+1) 1st-order Euler forward schemes, as well as 2nd-stage and 3rd- and 4th-stage Euler predictor-corrector (PC) schemes. Previous work has proved that the leapfrog scheme is neutrally stable with respect to the Coriolis force, with perfect inertial motion preservation, an amplification factor (AF) equal to unity, and a minor overestimation of the phase speed. The 1st-order Euler forward scheme, on the other hand, is known to be unconditionally inertially unstable since its AF is always greater than unity. In this study, it is shown that 3rd- and 4th-order predictor-corrector schemes 1) are inertially stable with weak damping if the Coriolis terms are equally split to n+1 (new value) and n (old value); and 2) introduce an artificial computational mode. The inevitable phase error associated with the Coriolis parameter is analyzed in depth for all numerical schemes. Some schemes (leapfrog and 2nd-stage PC schemes) overestimate the phase speed, while the others (1st-order Euler forward, 3rd- and 4th-stage PC schemes) underestimate it. To preserve phase speed as best as possible in a numerical model, alternating a scheme that overestimates the phase speed with a scheme that underestimates the phase speed is recommended. Considering all properties investigated, the leapfrog scheme is still highly recommended for a time integration scheme. As an example, a comparison between a leapfrog scheme and a 1st-order Euler forward scheme is presented to show that the leapfrog scheme reproduces much better vertical thermal stratification and circulation in the weakly-stratified Great Lakes.