bluuebunny/crossref_metadata_2025_split huggingface dataset:
Necrotizing Fasciitis? A Mimic Produced by an Unusual Presentation of Necrotizing Neutrophilic Dermatosis of the Hand
Authors: Abdul-Rassoul Hussein , Hight Robert , Chadha Angad , Strelzow Jason 
Published: August 2023

Case:
A 50-year-old woman presented to our emergency department with hand pain and a laceration. Despite administration of antibiotics, the patient progressively worsened leading to a concern for a necrotizing soft-tissue infection. She underwent multiple debridements yet continued to worsen clinically. Tissue biopsy was eventually consistent with a necrotizing neutrophilic dermatosis. The patient was then started on oral steroids with rapid improvement of her clinical status and hand examination.

Conclusion:
While neutrophilic dermatoses are rare, the orthopaedic surgeon treating soft-tissue infections should maintain a broad differential when treatment of a potential necrotizing infection has not led to diagnostic closure and clinical improvement.
Ulnar Nerve Compression at the Elbow Secondary to Intramuscular Lipoma of the Flexor Carpi Ulnaris
Authors: Tuaño Krystle R. , Fisher Marlie H. , Franzoni Demitri V. , Iorio Matthew L. 
Published: August 2023

Case:
A 62-year-old right-hand-dominant woman presented with 1 year of persistent radiating pain, weakness, and paresthesias in her left forearm and hand. Electromyography findings were significant for ulnar neuropathy distal to the branch innervating the flexor carpi ulnaris (FCU), without superimposed cervical radiculopathy or other focal entrapment neuropathy. During open ulnar nerve neurolysis, an intramuscular lipoma was encountered within the FCU. Lipoma excision and cubital tunnel release with ulnar nerve transposition were performed with complete relief of neuropraxia.

Conclusion:
We demonstrate full neurologic recovery after intramuscular lipoma excision and cubital tunnel release. Although rare, anomalous anatomy and tissue overgrowth should remain on the differential for patients presenting with atypical neuropraxia.
The Boundary Areas Structure of the Malko-Petropavlovsk Fracture Zone from Local Seismic Tomography and Earthquake Foci Mechanisms Data
Authors: Bushenkova N.A. , Kuchay O.A. 
Published: August 2023

Abstract
—This study continues analysis of the new seismic tomographic structure of the suprasubduction complex of the central zone of Kamchatka, obtained from the dense local networks data of 2018–2020, and is devoted to the analysis of the velocity structure in the Malko-Petropavlovsk fracture zone margins and around them. The seismic tomographic model involves about 98,000 P- and S-wave travel times from 2963 local earthquakes from August 2018 to July 2020. The resolution of this model makes it possible to trace the feeding systems of volcanoes of the South Kamchatka and East Volcanic Belt to the slab surface, as well as to identify subvertical structural faults. To construct the orientations of the compression and extension axes we used the foci mechanisms of 41 earthquakes with М ≥ 4.5 from the catalog of the International Seismological Center for the period 1979–2019. Along the Malko-Petropavlovsk fracture zone, the Avacha transform fault is clearly traced in the geometry and mutual arrangement of velocity anomalies almost throughout the entire depth of the model. Comparison of seismic anomalies with a map of the directions of the compression and extension axes distribution from the earthquake foci mechanisms showed the correlation between the change in the value of the velocity anomalies along the Avacha transform fault with the axes direction change by almost 180°. A near-surface low-velocity anomaly to the depths of 25–35 km was found along the western border of the Malko-Petropavlovsk zone under the southern tip of the Sredinny Ridge. This anomaly probably marks the axes junction zone boundary of the ancient volcanic front along the Sredinny Ridge and the modern active Eastern Volcanic Belt, which formed as a result of the Kronotsky paleoarc accretion. To the west from the Sredinny Ridge southern tip, another low-velocity anomaly was revealed. This anomaly was traced to a depth of ~150 km, has a contrasting southern boundary confirmed by the distribution of the compression and extension axes directions by the earthquake foci mechanisms and apparently marks the southern boundary of the West Kamchatka block.
Illusory ownership of one's younger face facilitates access to childhood episodic autobiographical memories
Authors: Gupta Utkarsh , Bright Peter , Clarke Alex , Zafar Waheeb , Recarte-Perez Pilar , Aspell Jane E. 
Published: August 2023

Abstract
Autobiographical memories are memories of previous experiences of one’s self, therefore it seems likely that autobiographical memories and self-representations interact in the brain. To test this in relation to the bodily self, we investigated whether the retrieval of childhood autobiographical memories would be facilitated by an illusion of ownership for a ‘child version’ of the participant’s own face. 50 neurologically healthy adults were tested in an online enfacement illusion study. Feelings of ownership and agency for the face were greater during conditions with visuo-motor synchrony than conditions with asynchrony. Critically, participants who viewed their child-like face recollected more childhood episodic memory details than those who viewed their adult face. No effects on autobiographical semantic memory recall were found. This finding indicates that there is an interaction between the bodily self and autobiographical memory. Our experimental paradigm could in future be adapted for its potential clinical application in memory disorders.
Diabetes Data Classification using Deep Learning Approach and Feature Selection based on Genetic
Authors: Abdollahi Jafar , NouriMoghaddam Babak , MIRZAEI ABBAS 
Published: August 2023

Abstract
The area of deep learning research (DL) has seen significant growth in recent years and has shown incredible promise for AI in medical applications. In this approach, we have proposed a deep neural network framework for the categorization of feature-based diabetes data. The dataset is classified using the SoftMax layer after features are collected from it using the wrapper approach. Additionally, the network is adjusted through supervised grid research with the training dataset. However, due to the risk of misdiagnosis in a medical context, we evaluated our model using measures such as precision, recall, specificity, and F1 score and obtained superior results. The proposed architecture has been tested using Diabetes 130-US hospital data, which consists of 100,000 patient files with an average of 55 attributes. As well, five machine learning algorithms—Nave Bayes, Random Forests, Decision Trees, Support vector machines, and Ensemble learning—are used to compare results from experiments. The classification accuracy of the ML algorithm was 86%. This research suggests a Deep Learning system based on feature selection for classifying diabetes data. This method has been tested on UCI machine learning data and has outperformed several other classification techniques, reaching 85.61% accuracy in this study.
Transcutaneous vagus nerve stimulation (tVNS) to acutely reduce emotional vulnerability and improve emotional regulation in borderline personality disorder (tVNS-BPD): study protocol for a randomized, single-blind, sham-controlled trial
Authors: Guerriero Giuseppe , Liljedahl Sophie , Carlsen Hanne , Muñoz Marta Lopez , Daros Alexander R. , Ruocco Anthony C. , Steingrimsson Steinn 
Published: August 2023

Abstract
Background: Borderline personality disorder (BPD) is considered a disorder of emotion regulation resulting from the expression of a biologically determined emotional vulnerability (that is, heightened sensitivity to emotion, increased emotional intensity/reactivity and a slow return to emotional baseline) combined with exposure to invalidating environments. Vagal tone has been associated with activity in cortical regions involved in emotion regulation and a lower resting state of vagal tone has been observed in BPD patients relative to healthy controls. Non-invasive transcutaneous vagus nerve stimulation (tVNS) has shown to reduce temper outbursts in adults with Prader-Willi Syndrome, to enhance recognition of emotions in healthy students and to improve depressive and anxiety symptoms. Furthermore, a single session of tVNS has been shown to acutely alter the recognition of facial expressions of negative valence in adolescents with MDD and increase emotion recognition in controls. However, the effect of tVNS on emotional vulnerability and regulation in individuals diagnosed with BPD has not been investigated. Our aims are to determine if tVNS is effective in acutely reducing emotional vulnerability and improve emotional regulation in BPD patients.
Methods: 42 patients will be randomized to a single session of tVNS or sham-tVNS while going through an affect induction procedure. It will consist of the presentation of one neutral and three negative affect-evoking 4-minutes-long videos in sequence, each of which is followed by a 4-minutes post-induction period during which participants will rate the quality and intensity of their current self-reported emotions (post-induction ratings) and the perceived effectiveness in managing their emotions during the video presentation. The rating of the current self-reported emotions will be repeated after every post-induction period (recovery ratings). Mixed models with individuals as random effect will be used to investigate the ratings at each stage of the study, taking into account the repeated measures of same individuals at baseline, pre-induction, post-induction and recovery).
Discussion: The study has potential to yield new insights into the role of vagal tone in emotion dysregulation in BPD and offer preliminary data on the effectiveness of tVNS as a possible non-invasive brain stimulation to treat a core symptom of BPD
Trial registration: ClinicalTrials.gov NCT05892900. Retrospectively registered on Jun 07, 2023. https://clinicaltrials.gov/show/NCT05892900.
Floral trait similarity and pollinator sharing between native and alien plants mediate heterospecific pollen transfer with consequences for pollination success
Authors: Parra-Tabla Victor , Albor Cristopher , Arceo-Gómez Gerardo 
Published: August 2023

Abstract
Heterospecific pollen transfer (HPT) is ubiquitous in co-flowering communities with strong implications for pollination success. Heterospecific pollen transfer may be especially relevant in invaded plant communities. The mechanisms mediating HPT in invaded communities however remain poorly understood even though it could help better understand the outcome of plant invasions. In this study, we use structural equation modeling to evaluate the role of floral trait similarity and pollinator sharing in HPT and pollination success of native plants in invaded coastal communities. Our results show that increased pollinator sharing between native and alien plants reduces total pollen loads on floral stigmas. In turn, an increase in total pollen load reduced proportion of heterospecific pollen (HP) but increased heterospecific pollen richness and the proportion of alien pollen (HPR and AHP respectively). The model showed that pollination success (i.e., proportion of pollen tubes) decreased with an increase in AHP but increased with increasing total HP. Unexpectedly, our results showed that floral trait similarity did not explain the degree of pollinator sharing. However, the proposed model suggested that increases in floral trait similarity and pollinator sharing negatively affect native pollination success. Our results also showed that increased pollinator sharing between native and alien plants increases pollination success, suggesting a facilitative effect of alien on native plants. Overall, our results highlight the importance of considering floral trait similarity and pollinator sharing in mediating the complex dynamic of HP transfer between native and alien plants and its consequences on native pollination success with implications for plant invasion success.
Morphologic and gene expression changes in Korean thyroid cancer cell lines under simulated ground-based microgravity
Authors: Yi Jin Wook , Ahn Jong-hyuk , yeon Park sung , Hwang young mi , Choi Yun Suk 
Published: August 2023

Abstract
Microgravity in space impacts human health. In particular, thyroid cancer, which has a high incidence rate, has been the subject of numerous studies with respect to microgravity. However, most studies have focused on European follicular thyroid cancer cell lines, while data regarding the effects of microgravity on Asian cell lines are lacking. Therefore, we aimed to investigate the effect of simulated ground-based microgravity on two Korean thyroid cancer cell lines, namely SNU-790 and SNU-80. We found that both cell lines formed multicellular spheroids under simulated microgravity. Gene expression analysis revealed that in SNU-790 cells, histone-related genes were upregulated and microRNA-related genes were downregulated. Meanwhile, in SNU-80 cells, genes related to the cellular response to hypoxia were downregulated. These findings contribute to a better understanding of the effects of microgravity on thyroid cancer cells. Further validation studies and clinical significance analyses are needed to fully understand the implications of these findings.
Evaluate the value of prolonging the duration of tiopronin for injection administration in preventing hepatotoxicity
Authors: yang Hongye , Lin Mingzhu , Liu Mengxing , Gu Huawei , Li Dan , Shi Yu , Hou Xidong 
Published: August 2023

Abstract
purpose：As part of supportive therapy, prophylaxis with tiopronin for injection (TI) against common hepatotoxicity complications has often been used. However, methods to prevent hepatotoxicity have not been established. Therefore, we analyzed the relationship between the periods of TI prophylaxis and its efficacy in preventing hepatotoxicity,evaluate the value of prolonging the duration of TI administration in preventing hepatotoxicity in gynecological cancer patients.
Methods This is a retrospective study. During 2022.1–2023.3, 452 patients with gynecological cancer patients were included in this study，the patient had normal liver function tests before treatment. The influencing factors of liver toxicity after treatment were analyzed, and different subgroups were divided according to the influencing factors. In total sample and different subgroups, we evaluated the prophylactic efficacy of TI by comparing the number of days of TI use. and the difference of the number of days of TI use on the prognosis of patients was compared in the total samples.
Results In total samples, there was no significant difference the effectiveness of TI with different prevention days for hepatotoxicity (P>0.05), and there was no significant difference in prognosis of tumor (P>0.05). The influencing factors of hepatotoxicity were the combinations of chemotherapeutic drugs,duration of chemotherapy drug use and the previous hepatotoxicity of patients. In different subgroups, there was no significant difference the effectiveness of TI with different prevention days for hepatotoxicity (P>0.05).
Conclusion TI is used as prophylactic drug in gynecological cancers, and prolonging periods of administration has no clinical value in preventing hepatotoxicity.
A novel application method of dung in restoring a degraded meadow steppe of Northern China
Authors: Hou Longyu , Bai Wenming , Sun Hailian , Liu Yahong , Luo Yingluo , Ma Xianxin , Tian Guiyun , Yu Hongxin , Liu Dewei , Li Aimin , Zhang Wen-Hao 
Published: August 2023

Abstract

The rapid increase in amount of dung by intensive livestock feeding has caused serious environmental problems. Natural grasslands are limited by nutrients’ availability while the dung contains nutrients that cannot be directly used by plants. The lack of effective way to release the plant available nutrients from dung greatly limits the use of dung in an environmentally friendly way. We developed a novel methodology to effectively use dung in restoration of degraded grasslands by applying dung with urea and decomposition inducer in a field experiment. We further explored the mechanisms underlying the positive effect of the combined application of dung, urea and the inducer on a degraded grassland by monitoring changes in soil, plant and community characteristics for three consecutive years under combined application of urea and dung (UD), urea, dung and decomposition inducer (UDI), and no application as control (CK) in a degraded meadow steppe in Northern China. Application of UD and UDI significantly increased soil moisture, soil total nutrients, available macronutrients, and vegetation indexes. Soil nutrients and vegetation indexes were significantly higher by application of UDI than that of UD. Soil moisture was found to be a main driving factor in aboveground biomass for each treatment. In contrast, aboveground biomass was positively related to both soil moisture and soil nutrients in each experimental year, regardless of treatments. When all data were pooled as a whole, structural equation modeling analysis indicated that the UDI-induced increase in aboveground biomass was achieved by both increasing soil moisture, and soil total nutrients and available nutrients. The inducer can accelerate dung decomposition and enhance release of nutrients from dung to soil, thus contributing to restoration of degraded grasslands. Our results demonstrate a novel way to directly use dung by combining application of urea, dung and decomposition inducer in restoration of degraded meadow steppe.
Maxillofacial trauma of equestrian origin: A retrospective study
Authors: Boiron Adeline , Barazer Camille , Clément Camille , Sahli-Vivicorsi Sonia , Bellamy Lorenn , Toux Guy Le , Boisramé Sylvie 
Published: August 2023

Abstract
Horse riding is a dangerous popular sport, it can causes facial traumas due to unpredictable reactions from the horse or falls. This study is a retrospective study about 20 patients. The aim of the study is analyze maxillofacial traumas with equine origin and discuss about prevention of those traumas. The admission period was from 2004 at 2021 and it takes place in emergency department of our university hospital in France. Inclusion criteria were patients who had suffered a maxillofacial trauma, admitted to the emergency department, and then to ENT and/or dentistry following an accident involving a horse. There were selected on the Health Data warehouse of our University Hospital. Thirty five medical files could be saved but 15 were not included because of the inclusion criteria. There were several studied parameters about patients: age, gender, date of injury, circumstances of injury, type of injury, management, helmet use, operative follow-up and possible sequelae. Patients were more women than men (16 versus 4), and there were young (half under 27 years old). There were more traumas in summer (80%). They concern most of the time ridder on foot (60%). 70% of the patients had at least one facial fracture. Only one case mentions helmet use. To conclude, horse riding can cause a various type of traumas. Treatments are various but sometimes surgery is necessary (only 7 of the 20 patients required just sutures). To avoid those traumas, the solution could be protective helmets, even when the ridder is on foot because in literature many of the traumas were due to lack of protective helmets.
Feedback Temperature Controller Design to a Semi-batch Hydrogenation Industrial Reactor - Part A: Modeling, Experimental Validation and Current Control System Evaluation
Authors: de Lima Fabrício Feijó , Batista Fabio Rodolfo Miguel , Guimarães Daniela Helena Pelegrine 
Published: August 2023

Abstract
Hydrogenation reaction normally is carried out in reactors that operate in batch or semi-batch, offering a high challenge for the implementation of efficient control systems for these processes. Therefore, the main aim of this paper was to model, simulate, validate and evaluate a real PI feedback controller applied to the control of temperature of a semi-batch industrial hydrogenation reactor. The mathematical model was considered very satisfactory since the average deviation between simulated reactor temperature and pressure and its real values were very low (0.173% and 3.74% for reactor temperature and pressure, respectively). The inlet pressures of the refrigerant and hydrogen were the main disturbs that affected the process, and the current PI controller was not able to control all the disturbances that occurred in these variables. Therefore, the development of a new control system is necessary, and will be modeled, simulated and discussed in part B of this paper.
Numerical model for calculation of Hydraulic Transients with two-phase flow and Fluid-Structure Interaction
Authors: Rocha Pedro Henrique do Nascimento , de Campos Josie Aguila Alves , Camargo Micelli Rodrigues , Rohca Marcelo da Silva 
Published: August 2023

Abstract
This paper presents a model for the solution of hydraulic transients with two-phase flow and fluid-structure interaction. Mathematical and numerical solutions are proposed and analyzed for the proper capture of the physical phenomena associated with the fluid compressibility and fluid celerity, which are variable in two-phase fluids, together with the disturbances generated by the fluid-structure interaction. The proposed solution for the model considers the simultaneous action of these phenomena. The developed numerical model is based on the solution of the mathematical model formed by a system of four partial differential equations, in which the necessary adaptations are integrated in fluid-structural equations and in the non-linear mathematical coefficients for the solution of the compressible and two-phase flow in question. Classical formulation is selected for the implementation of friction between fluid and pipe in the model. For the solution it is applied the method of characteristics and finite difference, with subsequent numerical integration. The validation of the results is carried out based on comparisons with experimental and analytical data.