bluuebunny/crossref_metadata_2025_split huggingface dataset:
Computational phenotypes for patients with opioid-related disorders presenting to the emergency department
Authors: Taylor R. Andrew , Gilson Aidan , Schulz Wade , Lopez Kevin , Young Patrick , Pandya Sameer , Coppi Andreas , Chartash David , Fiellin David , D’Onofrio Gail 
Published: September 2023

Objective
We aimed to discover computationally-derived phenotypes of opioid-related patient presentations to the ED via clinical notes and structured electronic health record (EHR) data.

Methods
This was a retrospective study of ED visits from 2013–2020 across ten sites within a regional healthcare network. We derived phenotypes from visits for patients ≥18 years of age with at least one prior or current documentation of an opioid-related diagnosis. Natural language processing was used to extract clinical entities from notes, which were combined with structured data within the EHR to create a set of features. We performed latent dirichlet allocation to identify topics within these features. Groups of patient presentations with similar attributes were identified by cluster analysis.

Results
In total 82,577 ED visits met inclusion criteria. The 30 topics were discovered ranging from those related to substance use disorder, chronic conditions, mental health, and medical management. Clustering on these topics identified nine unique cohorts with one-year survivals ranging from 84.2–96.8%, rates of one-year ED returns from 9–34%, rates of one-year opioid event 10–17%, rates of medications for opioid use disorder from 17–43%, and a median Carlson comorbidity index of 2–8. Two cohorts of phenotypes were identified related to chronic substance use disorder, or acute overdose.

Conclusions
Our results indicate distinct phenotypic clusters with varying patient-oriented outcomes which provide future targets better allocation of resources and therapeutics. This highlights the heterogeneity of the overall population, and the need to develop targeted interventions for each population.
Randomized Trial of Prophylactic Antibiotics for Endoscopic Retrograde Cholangiopancreatography in Patients With Biliary Obstruction
Authors: Leem Galam , Sung Min Je , Park Ji Hoon , Kim So Jeong , Jo Jung Hyun , Lee Hee Seung , Ku Nam Su , Park Jeong Youp , Bang Seungmin , Park Seung Woo , Song Si Young , Chung Moon Jae 
Published: September 2023

INTRODUCTION:
The incidence of postendoscopic retrograde cholangiopancreatography (ERCP) infections is reported to be up to 18% in patients with biliary obstruction. Antibiotic prophylaxis may reduce the risk of infectious complications after ERCP; however, the clinical value of prophylactic antibiotics in ERCP remains controversial.

METHODS:
We conducted a double-blind, placebo-controlled, randomized trial to investigate whether the use of prophylactic antibiotics would reduce infectious complications after ERCP in patients with biliary obstruction. We randomly assigned patients in a 1:1 ratio to receive either a single dose of 1 g intravenous cefoxitin or normal saline as a placebo 30 minutes before undergoing ERCP. The primary outcome was the incidence of infectious complications after ERCP.

RESULTS:
We enrolled 378 patients, and 189 patients were assigned to each group. The risk of infectious complications after ERCP was 2.8% (5 of 176 patients) in the antibiotic prophylaxis group and 9.8% (17 of 173 patients) in the placebo group (risk ratio, 0.29; 95% confidence interval [CI], 0.11–0.74, P = 0.0073). The incidence rates of bacteremia were 2.3% (4 of 176 patients) and 6.4% (11 of 173 patients), respectively (risk ratio, 0.36; 95% CI, 0.12–1.04; P = 0.0599). The incidence rate of cholangitis was 1.7% (3 of 176 patients) in the antibiotic prophylaxis group and 6.4% (11 of 173 patients) in the placebo group (risk ratio, 0.27; 95% CI, 0.08–0.87; P = 0.0267).

DISCUSSION:
Antibiotic prophylaxis before ERCP in patients with biliary obstruction resulted in a significantly lower risk of infectious complications, especially cholangitis, than placebo (ClinicalTrials.gov trial number NCT02958059).
Contaminant curiosity and pollutant puzzles: Conceptual insights in ecotoxicity and practical implementation of higher-tiered risk assessment.
Authors: Vink Jos P.M. , Vijver Martina G. , Hendriks A. Jan 
Published: September 2023

Abstract
Since the soil quality Tool for Risk Identification, Assessment and Display (TRIAD) approach introduced the “three lines of evidence” accounting for chemical, toxicological and ecological stressors to explain adverse effects in biota, the assessment of contaminant risks in the environment has significantly evolved. The concept of chemical speciation, related to water characteristics, boosted the understanding of the role of free-ion activities in the overall accumulation of pollutants in biota. New modeling concepts (e.g. biotic ligand models) and measuring techniques were developed. This in turn triggered widespread research addressing the quantitative role of sediment in the overall water quality, focusing on redox interfaces. For contaminant mixtures in river catchments, complex relations between (bio)availability of compounds, including nutrients, help to explain aquatic toxicity. Variation in ecological patterns and processes across environmental or spatiotemporal gradients occur, which may identify ecological factors that influence contaminant fate and effects. Empirical evidence by meta-analysis and theoretical underpinning by modelling showed relationships between population growth rates and carrying capacities, across chemicals and across species. The potentially affected fraction of species may be related to the mean species abundance, an often-used indicator in global change studies. Knowledge gaps remain on how pollutants travel through ecological communities and which species and species-relationships are affected. Outdoor experimental systems that examine the natural environment under controlled conditions may be useful at the higher biological level to investigate the impact of stressors on a variety of species, including mutual interactions.
Pengembangan masyarakat berbasis Gender: Analisis Program Dana Desa dan Program Keluarga Harapan
Authors: Alfrojems Alfrojems , Chairani  , Anugrahini Triyanti 
Published: September 2023

The purpose of this research is to examine gender issues in community development efforts through poverty alleviation programs, particularly the Village Fund and the Conditional Cash Transfer (PKH) program. The method employed in this writing is a literature review. Data collection was carried out by gathering journals, reports, books, and documents relevant to the research objectives. Based on the findings of the review, it is evident that gender-related problems in poverty alleviation efforts are not limited to within the community; they also extend to the implementation of gender concepts within government programs. This can be observed in the two aspects discussed in this paper: gender in community development and gender in government programs. The recommendations derived from this study that need to be implemented include the necessity for policy reviews, policy adjustments, capacity building for facilitators, the development of gender-related instruments, the promotion of collaborations with universities, and the encouragement of more publications relevant to gender issues.
Keywords: Gender, Poverty Alleviation, Community Development, PKH

Tujuan penelitian ini mengkaji isu gender dalam upaya pengembangan masyarakat melalui program pengentasan kemiskinan khususnya pada program Dana Desa dan PKH. Metode yang digunakan dalam penulisan ini adalah kajian literatur. Pengumpulan data dilakukan melalui pengumpulan data berupa jurnal, laporan, buku, dan dokumen yang relevan dengan tujuan penelitian. Berdasarkan hasil pengkajian maka diperoleh bahwa persoalan gender dalam upaya pengentasan kemiskinan bukan hanya terjadi di tengah masyarakat, bahkan juga pada implementasi konsep gender pada program pemerintah, hal ini dapat dilihat pada dua aspek pembahasan penulisan ini yakni gender pada pengembangan masyarakat dan gender dalam program pemerintah. Adapun rekomendasi dari penelitian ini yang perlu untuk dilaksanakan adalah perlunya upaya untuk melakukan reviu kebijakan, penyesuaian kebijakan, peningkatan kapasitas terhadap pendamping, penyusunan instrumen terkait dengan gender, mendorong kerjasama dengan perguruan tinggi, dan mendorong untuk semakin banyaknya publikasi yang relevan dengan isu gender.
Kata Kunci: Gender, Pengentasan Kemiskinan, Pengembangan Masyarakat, PKH
Faktor Sosio-Demografi yang Berhubungan dengan Penggunaan Suplemen dan Jamu selama Pandemi: Studi Kasus pada Mahasiswa UNIPMA Tahun 2022
Authors: Kartini Puri Ratna , Kusumawati Desi , Kusuma Ajeng Probo , Wisnubroto Agung Prabowo 
Published: September 2023

Background: Corona Virus Disease 19 (COVID-19) is a global pandemic declared in 2020 by WHO. The high incidence and death rates of COVID-19 affect human social activities in all countries, including Indonesia. This pandemic has had an impact on various sectors including education. Students are one of the groups prone to contracting COVID-19 from the campus cluster. So it is necessary to strengthen one's immunity by consuming supplements and herbs. This study aims to analyze socio-demographic factors related to the use of supplements and herbs in UNIPMA students.Methods: This research is an analytic observational study (cross-sectional design) in which the researcher conducted indirect interviews using a questionnaire instrument distributed through the media google form. This study involved 361 UNIPMA students using a purposive sampling technique. Then the results of the study were analyzed using the chi square test.Result: Based on statistical tests, the results obtained for the gender variable were p = 0.014, the type of study program variable was p = 0.011, the income variable of both parents was p = 0.679 and the access variable to pharmacies and drug stores was p = 0.193.Conclusion : Based on the research results, it can be concluded that socio-demographic factors related to the use of supplements and herbs in UNIPMA students are gender and type of study program. Meanwhile, socio-demographic factors such as the income of both parents and access to pharmacies and drug stores are not related to the use of supplements and herbs in UNIPMA students.
Progressive Partitioning for Parallelized Query Execution in Google's Napa
Authors: Tatemura Junichi , Zou Tao , Sankaranarayanan Jagan , Huang Yanlai , Chen Jim , Zhang Yupu , Lai Kevin , Zhang Hao , Manoharan Gokul Nath Babu , Graefe Goetz , Agrawal Divyakant , Adelberg Brad , Kolhar Shilpa , Roy Indrajit 
Published: September 2023

Napa holds Google's critical data warehouses in log-structured merge trees for real-time data ingestion and sub-second response for billions of queries per day. These queries are often multi-key look-ups in highly skewed tables and indexes.
In our production experience, only progressive query-specific partitioning can achieve Napa's strict query latency SLOs. Here we advocate good-enough partitioning that keeps the per-query partitioning time low without risking uneven work distribution. Our design combines pragmatic system choices and algorithmic innovations. For instance, B-trees are augmented with statistics of key distributions, thus serving the dual purpose of aiding lookups and partitioning. Furthermore, progressive partitioning is designed to be "good enough" thereby balancing partitioning time with performance. The resulting system is robust and successfully serves day-in-day-out billions of queries with very high quality of service forming a core infrastructure at Google.
Kant’s Semiotics and Hermeneutics in the 1760s
Authors: Costantini Marco 
Published: September 2023

Abstract
In this contribution, we first discuss the aspects of the analytic method conceived by Kant in the Deutlichkeit that differentiate it from the Wolffian method and relate it to the Newtonian method. Compared to the philosophical tradition, the task of analysing concepts appears profoundly changed. Since Kant aims philosophy towards the world, he considers concepts as something given and intends to discern their characteristic marks by observing their usual applications. Although Kant abandons any attempt to define concepts nominally, he still gives great relevance to words to the extent that concepts, according to him, acquire their meaning in the linguistic usage. We will also point out how for Kant the linguistic usage makes the analysis of concepts anything but easy and how a hermeneutic process is necessary for its completion. In distinguishing philosophical signs from mathematical signs, Kant provides the semiotic reasons that underlie his recourse to hermeneutics.
Kant on Language and the (Self‐)Development of Reason
Authors: Lu-Adler Huaping 
Published: September 2023

Abstract
The origin of languages was a hotly debated topic in the eighteenth century. This paper reconstructs a distinctively Kantian account according to which the origination, progression, and diversification of languages is at bottom reason’s self-development under certain a priori constraints and external environments. The reconstruction builds on three sets of materials. The first is Herder’s famous prize essay on the origin of languages. The second includes Kant’s explicit remarks about language – especially his notion of “transcendental grammar,” his argument that language cannot be innate, his contrast of “Oriental” symbolic (intuitive) and “Occidental” discursive languages, and his treatment of the latter as a sine qua non of humanity’s cultural and moral progress. The third includes the concepts that we need to make sense of those remarks, such as Kant’s epigenetic theory of biological formation and his account of categories as originally acquired.
Traces of a “new” Metalcraft Specialisation: A unique Late Bronze Age Burial at Karzec Cemetery
Authors: Stróżyk Mateusz , Garbacz-Klempka Aldona , Wardas-Lasoń Marta , Silska Patrycja , Wrzesińska Anna 
Published: September 2023

Abstract
This paper will discuss the results of material science analyses of artefacts from grave no. 89 in Karzec, Central Poland, that were discovered in 1959. The obtained results will be interpreted in the context of the possibility of a ‘new’ specialisation within the metallurgical workshop of the Lusatian people of the Late Bronze Age – a mouldmaker/moulder. In many terms, the grave at Karzec is a unique object for the study of Bronze Age metallurgy, as it contained not only two complete stone casting moulds but also pre-prepared raw material for the production of another mould as well as other metalworking objects. Despite this fact, it has yet to be the subject of a detailed analysis.
Spiritualität im Kontext von Demenzerkrankungen. Ethische Anforderungen für eine ganzheitliche Betreuung am Lebensende.
Authors: Kropf Mario 
Published: September 2023

Zusammenfassung
Für die Behandlung und Versorgung von Menschen am Lebensende sind vielfach die medizinischen Interventionsmöglichkeiten nicht mehr ausreichend oder sinnvoll, um kurativ tätig zu werden. Seit einigen Jahren hat sich auch deshalb der Begriff „Spiritualität“ zu einem Schlagwort des medizinischen und pflegerischen Settings etabliert. Dadurch werden beispielsweise eigene Bewältigungsstrategien von Individuen ermöglicht und deren Umgang mit Gesundheit und Krankheit gefördert, ohne dabei unbedingt auf religiöse Überzeugungen zu bauen. Fraglich ist jedoch, was genau unter Spiritualität überhaupt zu verstehen ist, weshalb in diesem Beitrag zunächst ein Verständnis von Spiritualität dargestellt wird. Eine Demenzerkrankung führt zur Abnahme der kognitiven Leistungsfähigkeit und im Allgemeinen der selbständigen Lebensführung. Inwiefern sich im Kontext dieser neurodegenerativen Erkrankung eine Form von Spiritualität als brauchbar und sinnstiftend erweisen kann, wird in einem zweiten Schritt erörtert. Anschließend werden die Überlegungen zu Spiritualität bzw. Demenz zusammengeführt und gefragt, wie man vor diesem Hintergrund Personen am Ende ihres Lebens mit Wohlwollen und Mitgefühl begegnen kann. Wesentlich ist ein Fokus auf spirituelle Gesichtspunkte von allen Beteiligten, wozu die medizinischen Fachleute zählen, die Angehörigen, die Betroffenen selbst und deren Pflegepersonal. Nur so lässt sich eine ethische Orientierung im Handeln und Entscheiden umsetzen, indem die Aspekte der Ganzheitlichkeit beachtet und spirituelle Momente ermöglicht werden.
Survei Ketersediaan dan Kelayakan Sarana dan Prasarana Penjasorkes di SMA Negeri se-Kabupaten Purworejo
Authors: Abdullah Surya , Supriyono Supriyono 
Published: September 2023

The purpose of this study was to determine the availability and feasibility of facilities and infrastructure in public high schools in Purworejo Regency. In this study using a method approach mixed, the subjects in this study were Physical Education teachers at SMA Negeri Purworejo, namely 11 teachers. The data was obtained from the process of questionnaires, interviews, observations, and documentation. Then the data analysis technique using descriptive percentage and data reduction techniques. This study obtained results from physical education teachers in the form of: for the availability of facilities and infrastructure for SMA Negeri Purworejo, the category was very good with a percentage of 74.17%, sufficient category 8.88% and less category 16.94%. Then in terms of feasibility, the facility and infrastructure in each school are very decent, not damaged, far from danger, etc. The conclusion from this research is that the overall availability and feasibility of facilities and infrastructure in Purworejo Regency is very good and very feasible. Suggestions for Physical Education teachers to maintain and maximize existing facilities and infrastructure for better learning
Pengembangan Model Latihan Jatuhan Pencak Silat Di Ekstrakurikuler Tingkat SMP Kota Semarang
Authors: Khoirul Ibnu , Setiawan Ipang 
Published: September 2023

Penguasaan gerak jatuhan pencak silat setiap peserta pada suatu tempat latihan tentu berbeda-beda. Dari data observasi awal menunjukkan sebagian besar siswa sangat kesulitan melakukan gerak latihan jatuhan pencak silat. Pembuatan variasi model latihan merupakan upaya untuk menuntaskan permasalahan. Permasalahan pada penelitian ini yaitu Bagaimana bentuk pengembangan model latihan jatuhan pada pencak silat di ekstrakurikuler tingkat Sekolah Menengah Pertama ?. Tujuan penelitian ini untuk menghasilkan dan mengetahui efektifitas dari pengembangan model latihan jatuhan pencak silat. Penelitian ini menggunakan metode penelitian pengembangan yang mengacu pada model pengembangan dari Brog & Gall. Penelitian ini memperoleh hasil dari uji coba skala kecil mendapatkan rata-rata dari kuesioner sebesar 86,37% dan hasil wawancara sebesar 98,43 % (Sangat Positif). Sedangkan pada uji coba skala besar diperoleh presentase 85,47 %, dan presentase hasil tes wawancara sebesar 99,13 %. Berdasarkan hasil tersebut diperoleh rata-rata presentase sebesar 89,01% (Sangat Positif).
Analisis Rencana Pelaksanaan Pembelajaran Kelas X Mapel PJOK Ditinjau dari HOTS di SMK Se-Kecamatan Kebumen
Authors: Salamah Nahar , Raharjo Hermawan Pamot 
Published: September 2023

This study aims to analyze how well the class X PJOK RPP is about learning based on Higher Order Thinking Skills in SMKs in Kebumen District. This research is quantitative descriptive. The method in this research is survey. The population in this study were all PE teachers in SMK throughout Kebumen District The data analysis technique of this research is descriptive analysis. The results of the analysis of the lesson plan analysis for Class X Mapel PE in Vocational Schools throughout the Kebumen District in terms of HOTS showed the "very good" category with a percentage of 30%, the "good" category with a percentage of 30%, the "enough" category with a percentage of 30%, the category " less” with a percentage of 0%, the category of “very poor” with a percentage of 10%. From the results of the study, it can be concluded that the PE teachers in Vocational Schools throughout the Kebumen District have prepared the RPP properly and in accordance with the HOTS. Suggestions that researchers can give for PE teachers whose RPP is still in the sufficient category, the teacher should use operational verbs C4, C5, and C6, in choosing the method the teacher should use Discovery/Inquiry Learning, Problem based Learning, Project
Pelaksanaan Penilaian Hasil Pembelajaran Pendidikan Jasmani pada Siswa Tuna Grahita SLB Se-Kota Semarang
Authors: Fahmi Harinda , Akhiruyanto Andry 
Published: September 2023

The purpose of this study was to determine the implementation of the assessment of physical education learning outcomes from the cognitive, affective, and psychomotor aspects of mentally retarded students in SLB Semarang City.This study uses a qualitative research method with a descriptive approach. Data collection techniques are carried out by observation, interviews, and documentation. The validity of the data is done by triangulation. Data analysis was carried out by collecting data, reducing data, presenting data, and drawing conclusions. The results showed that the implementation of the assessment of physical education learning outcomes from the cognitive aspect is given based on the knowledge ability of each student. Assessment of the affective aspect is given based on the ability and character of each student. Assessment of the psychomotor aspect is given based on the ability of the skills of each student.
The Relationship between Cash Ratio and Firm Profitability Applied Study on Egyptian Stock Market
Authors: Srour Heba , Srour Mohamed 
Published: September 2023

Purpose: This paper investigates the relationship between CaHR and firm financial profitability applying to the Egyptian stock market. Methodology: OLS regression analysis is conducted to explain the 2 models used for a sample of (10) Egyptian Companies during the period between 2013 to 2021. The main hypothesis is tested H1: There is no a statistically significant relationship between CaHR and firm profitability. Findings: The independent variables (CaHR, Lev) have a negative effect on ROA-ROE, and the independent variables (size, AG) have a positive effect on ROA-ROE, but all independent variables have a statistically significant relationship on ROA-ROE, and thus the study's main hypothesis was rejected. Research limitations: The paper opens the area for future research by using a distinct dataset that includes the time period during and after the COVID-19 epidemic to capture the impact of covid-19 on the firm liquidity and profitability.