bluuebunny/crossref_metadata_2025_split huggingface dataset:
A vignette study of mental health literacy for binge-eating disorder in a self-selected community sample
Authors: Hollett Kayla B. , Pennell Jenna M. , Carter Jacqueline C. 
Published: May 2023

Abstract
Background
Mental health literacy has implications for mental disorder recognition, help-seeking, and stigma reduction. Research on binge-eating disorder mental health literacy (BED MHL) is limited. To address this gap, our study examined BED MHL in a community sample.

Method
Two hundred and thirty-five participants completed an online survey. Participants read a vignette depicting a female character with BED then completed a questionnaire to assess five components of BED MHL (problem recognition, perceived causes, beliefs about treatment, expected helpfulness of interventions, and expected prognosis).

Results
About half of participants correctly identified BED as the character’s main problem (58.7%). The most frequently selected cause of the problem was psychological factors (46.8%) and a majority indicated that the character should seek professional help (91.9%). When provided a list of possible interventions, participants endorsed psychologist the most (77.9%).

Conclusions
Compared to previous studies, our findings suggest that current BED MHL among members of the public is better, but further improvements are needed. Initiatives to increase knowledge and awareness about the symptoms, causes, and treatments for BED may improve symptom recognition, help-seeking, and reduce stigma.
The spatial properties of the site amplifications of S-waves by generalized spectral inversion technique and the correction method of the site amplifications considering the contribution of later arrivals after major S-waves
Authors: Nakano Kenichi , Kawase Hiroshi 
Published: May 2023

AbstractSite amplification is an important component of strong ground motion prediction as it differs among sites, reflecting its specific local subsurface geology. Here, we confirm that site amplifications are similar in a neighborhood area over a long period. However, few studies have investigated the spatial properties in a wide region (i.e., the whole of Japan). In this study, we explored the spatial properties of site amplifications based on the generalized inversion technique (GIT) using Fourier amplitude spectra (FAS) as well as pseudo-velocity response spectra (pSv) as the latter is an important index for engineering purposes and the most similar type of response spectra to FAS. The spatial distributions of S-wave site amplifications (SA-S), especially within large sediment basins (e.g., the Kanto and Osaka Basins in Japan), were found to be relatively similar in proximate areas for a long period ranging from 2 to 8 s. This suggests that we could easily predict the site amplifications using an empirical approach through spatial interpolation based on the properties obtained by the GIT. Furthermore, we propose a prediction procedure for site amplification for the whole duration from the SA-S at an arbitrary site. We used the correction function, which converts the SA-S to the site amplification for the whole duration (SA-W), including an S-wave portion and a subsequent portion. This function is called the whole-duration to S-wave spectral ratio (WSR) and is stable in terms of spatial properties. As we could estimate the SA-S either by theoretical transfer functions or observed microtremors, we can easily predict the SA-W based on the proposed WSR concept. We found that SA-S in pSv is more or less similar to SA-S in FAS, however, SA-W in pSv fails to capture the effects of the long duration of ground motions inside a large basin so that we cannot recommend to use pSv for the prediction of whole duration of ground motion.
Graphical Abstract
Conjugate observations of power line harmonic radiation onboard DEMETER
Authors: Wu Jing , Wang Zhengkai , Zhang Jingwen , Yue Chao , Xie Li 
Published: May 2023

AbstractThe effects of power line harmonic radiation (PLHR) on near-Earth space have been debated for many years. Since some ultrahigh voltage AC and DC power projects were added to the Chinese power grid, increasingly numerous radiations at 50 Hz and their harmonics have been caught by the microsatellite DEMETER in the geomagnetically conjugate topside ionosphere during the daytime of winter and spring. Distribution of SYM-H index has been studied, showing geomagnetic disturbances may be unnecessary for the occurrence of PLHR. The propagation of PLHR between hemispheres without much attenuation illustrates that PLHR can be amplified when crosses the equatorial zone. Eliminating seasonal and diurnal factors, dependence of PLHR propagation on the change in plasma density is disclosed. The abrupt variation of electron density gradient may create a favored condition for PLHR waves propagating between hemispheres.
Graphical Abstract
Nonadherence to antiasthmatic medications and its predictors among asthmatic patients in public hospitals of Bahir Dar City, North West Ethiopia: using ASK-12 tool
Authors: Demelash Teshome Bitew , Asmamaw Getahun , Limenh Liknaw Workie , Anagaw Yeniewa Kerie , Simegn Wudneh , Ayenew Wondim 
Published: May 2023

Abstract
Background
Globally, adequate asthma control is not yet achieved. The main cause of uncontrollability is nonadherence to prescribed medications.

Objectives
The objective of this study is to assess asthmatic patients' non-adherence to anti-asthmatic medications and the predictors associated with non-adherence.

Methods
An institution-based cross-sectional study was conducted in three governmental hospitals in Bahir Dar city from September 5 to December 12, 2021. The data was collected using the Adherence Starts with Knowledge-12 tool (ASK-12). Systematic random sampling was applied to select study participants. Bivariable and multivariable logistic regression analyses were used to identify predictors of non-adherence. All statistical tests were analyzed using STATA version 16. P-values less than 0.05 were considered statistically significant.

Results
A total of 422 asthmatic patients were included in the study. Most of the study participants (55.4%) did not adhere to their prescribed anti-asthmatic medicines. The educational status of the study participants (AOR = 0.03, 95% CI = 0.00–0.05), family history of asthma (AOR = 0.13, 95% CI = 0.04–0.21), and disease duration that the patients were living with (AOR = 0.01, 95% CI = 0.00–0.01) were the predictors of non-adherence to anti-asthmatic medications.

Conclusions
The level of nonadherence to treatment among patients with asthma was high. Religion, educational status of study participants, family history of asthma, and duration of the disease were the predictors of non-adherence of asthmatic patients to their antiasthmatic medications. Therefore, the Ministry of health, health policy makers, clinicians, and other healthcare providers should pay attention to strengthening the adherence level to antiasthmatic medications, and country-based interventions should be developed to reduce the burden of non-adherence to anti-asthmatic medications.
Determinants of long act reversible contraceptive utilization among HIV positive reproductive age women attending ART clinic in South West Ethiopia
Authors: Kefeni Bilisumamulifna Tefera , Tesfaye Sitota , Bayisa Kenbon , Negara Ebissa , Bati Feyiso 
Published: May 2023

Abstract
Background
Identifying the determinants of long-acting contraceptive utilization and managing the sexual and reproductive health of HIV-infected women is critical to reducing HIV transmission and maternal mortality. However, the determinants of long-acting contraceptive utilization have not been well understood in resource-limited settings like Ethiopia. The aim of this study was to identify determinants of long-acting reversible contraceptive utilization among HIV-positive women on ART in southwest Ethiopia.

Methods
A facility-based, unmatched case control study was conducted from July 24 to August 28, 2021, in south-west Ethiopia. The study participants were HIV positive women, with a sample size of 109 cases and controls. An interviewer administered a questionnaire, and a check list was used for data collection. A systemic random sampling technique was used to collect data from cases and controls. Bivariate and multivariable logistic regressions were employed to determine the determinants of LARC utilization among HIV-positive women. To demonstrate the strength of the determinant, the odds ratio was calculated with 95% confidence intervals, and a P-value less than 0.05 was used to declare statistical significance.

Result
A total of 324 women (108 cases and 216 controls) of reproductive age who were HIV positive were interviewed, with a response rate of 99.0%. urban residence (AOR = 2.67, 95%CI: 1.23- 5.77), having formal education (AOR = 2.93, 95% CI:1.36, 6.34), being counseled by health care provider (AOR = 5.42,95% CI: 2.67–11.03), no future fertility intention (AOR = 2.87, 95% CI:1.44–5.70), having CD4 count less than 500 cell/mm3 (AOR = 4.18,95% CI:2.12–8.23), having information of HIV transmission from mother to child (AOR = 3.65,95% CI:1.49–8.95),not using condom during sexual intercourse (AOR = 4.86,95% CI:2.46–9.62),,having knowledge towards LARC (AOR = 2.38,95% CI:1.24–4.58) and attitude towards LARC (AOR = 6.41,95%CI:3.16–13.0) were independent determinants of LARC utilization among HIV positive women.

Conclusion and recommendation
Women being counseled by a health care provider, having no future fertility intention, and having a CD4 count less than 500 cells/mm3 were found to be determinants of long-acting contraceptive method utilization among HIV-positive reproductive-age women. Also, our study supports the WHO Strategic Concepts for Improving the Links between Family Planning and HIV/AIDS Policy, Programs, and Services. It is recommended that Health care providers should use these factors as base line during family planning counseling and service delivery.
Two promising larval parasitoids, Bracon (Habrobracon) didemie and Dolichogenidea appellator (Hymenoptera: Braconidae) for biological control of Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae)
Authors: Karut Kamil , Karaca Mahmut Mete , Döker İsmail , Kazak Cengiz 
Published: May 2023

Abstract
Background
The tomato leafminer, Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae), is one of the most important tomato pests that causes irreversible economic losses. Due to lack of effective control methods, chemical control is still the most preferred approach for management of the pest all over the world. Therefore, researches are mainly focused on implementing a sustainable pest control program against this pest through finding out effective natural enemies. For this purpose, a survey study was conducted to determine the larval parasitoids of T. absoluta in field-grown tomatoes in Adana, Turkey, in 2021–2022.

Results
Two larval parasitoids, Bracon (Habrobracon) didemie Beyarslan and Dolichogenidea appellator (Telenga) (Hymenoptera: Braconidae), were identified morphologically and molecularly. The first parasitoid populations were observed in tomato fields at the end of June and were maintained until the tomato plants were cleared (Middle of July). Throughout the survey, B. didemie was determined to be the more prevalent species than D. appellator. The highest percentage of D. appellator was found in the last week of June in 2021, at 42.8%. When the parasitoid species densities were compared, B. didemie accounted for 93.2% of the total parasitoids. Despite the intensive use of insecticides, the highest parasitoid density was achieved by B. didemie as 28 individuals per 100 leaves.

Conclusions
Based on these results, it was concluded that B. didemie can be candidate as a successful biological control agent against T. absoluta in tomato field as a part of IPM programs.
Antibiotics for treatment of apical periodontitis, indication or contraindication
Authors: Heta Saimir , Alliu Nevila , Robo Ilma , Ostreni Vera 
Published: May 2023

AbstractBackgroundApical periodontitis as an endodontic diagnosis has attracted attention for the close relationship between the periodontal nature and the endodontic nature that this pathology represents. The appearance of pathology in periodontal tissues, but originating from the infected canal of the affected tooth, is caused by the passage of pulpal infection–inflammation products only between the apical foramen toward the periodontal tissues positioned at the exit of the tooth canal. Depending on the morphology of the canal, it can be one inflamed area, or several that form a whole, if the pulp has terminal branches, like “river delta,” in its apical exit.Main body of the abstractThe study aims to evaluate the clinical significance whether to treat or not with antibiotics of apical periodontitis. This study aims to look at this pathology from the perspective of the articles already published in the literature and after processing the conclusions of all the articles, come up with current recommendations on the treatment or not with antibiotics of the clinical cases presented with the pathology of the apical periodontium.ResultsThe classification of apical periodontitis occurs depending on the clinical signs visible with radiographs and the objective and subjective complaints of the patient. Regardless of subclassifications of apical periodontitis, the cause is bacteria or symbiosis of bacteria causing pulpitis, so as in any bacterial infection there is a tendency to treat them with antibiotics locally rather than in a systemic way, as long as the infection does not cause systemic symptoms such as fever, or massive swelling of the affected area.Short conclusionFrom the analysis of the collected information, it is clear that the trend for treatment of apical periodontitis in the future does not lie in the application of antibiotics, but rather in irrigation solutions or the use of devices for the purpose of disinfecting the canal affected by the pathology. However, in no case is it indicated to eliminate the mechanochemical canal cleaning protocol before applying any type of treatment methodology.
Organizational readiness to implement task-strengthening strategy for hypertension management among people living with HIV in Nigeria
Authors: Iwelunmor Juliet , Ogedegbe Gbenga , Dulli Lisa , Aifah Angela , Nwaozuru Ucheoma , Obiezu-Umeh Chisom , Onakomaiya Deborah , Rakhra Ashlin , Mishra Shivani , Colvin Calvin L. , Adeoti Ebenezer , Badejo Okikiolu , Murray Kate , Uguru Henry , Shedul Gabriel , Hade Erinn M. , Henry Daniel , Igbong Ayei , Lew Daphne , Bansal Geetha P. , Ojji Dike 
Published: May 2023

Abstract
Background
Hypertension (HTN) is highly prevalent among people living with HIV (PLHIV), but there is limited access to standardized HTN management strategies in public primary healthcare facilities in Nigeria. The shortage of trained healthcare providers in Nigeria is an important contributor to the increased unmet need for HTN management among PLHIV. Evidence-based TAsk-Strengthening Strategies for HTN control (TASSH) have shown promise to address this gap in other resource-constrained settings. However, little is known regarding primary health care facilities’ capacity to implement this strategy. The objective of this study was to determine primary healthcare facilities’ readiness to implement TASSH among PLHIV in Nigeria.

Methods
This study was conducted with purposively selected healthcare providers at fifty-nine primary healthcare facilities in Akwa-Ibom State, Nigeria. Healthcare facility readiness data were measured using the Organizational Readiness to Change Assessment (ORCA) tool. ORCA is based on the Promoting Action on Research Implementation in Health Services (PARIHS) framework that identifies evidence, context, and facilitation as the key factors for effective knowledge translation. Quantitative data were analyzed using descriptive statistics (including mean ORCA subscales). We focused on the ORCA context domain, and responses were scored on a 5-point Likert scale, with 1 corresponding to disagree strongly.

Findings
Fifty-nine healthcare providers (mean age 45; standard deviation [SD]: 7.4, 88% female, 68% with technical training, 56% nurses, 56% with 1–5 years providing HIV care) participated in the study. Most healthcare providers provide care to 11–30 patients living with HIV per month in their health facility, with about 42% of providers reporting that they see between 1 and 10 patients with HTN each month. Overall, staff culture (mean 4.9 [0.4]), leadership support (mean 4.9 [0.4]), and measurement/evidence-assessment (mean 4.6 [0.5]) were the topped-scored ORCA subscales, while scores on facility resources (mean 3.6 [0.8]) were the lowest.

Conclusion
Findings show organizational support for innovation and the health providers at the participating health facilities. However, a concerted effort is needed to promote training capabilities and resources to deliver services within these primary healthcare facilities. These results are invaluable in developing future strategies to improve the integration, adoption, and sustainability of TASSH in primary healthcare facilities in Nigeria.

Trial registration
NCT05031819.
Equity of Cancer and Diabetes Co-Occurrence: A National Study With 44 Million Person-Years of Follow-Up
Authors: Gurney Jason , Stanley James , Teng Andrea , Robson Bridget , Scott Nina , Sika-Paotonu Dianne , Lao Chunhuan , Lawrenson Ross , Krebs Jeremy , Koea Jonathan 
Published: May 2023

PURPOSE The co-occurrence of diabetes and cancer is becoming increasingly common, and this is likely to compound existing inequities in outcomes from both conditions within populations. METHODS In this study, we investigate the co-occurrence of cancer and diabetes by ethnic groups in New Zealand. National-level diabetes and cancer data on nearly five million individuals over 44 million person-years were used to describe the rate of cancer in a national prevalent cohort of peoples with diabetes versus those without diabetes, by ethnic group (Māori, Pacific, South Asian, Other Asian, and European peoples). RESULTS The rate of cancer was greater for those with diabetes regardless of ethnic group (age-adjusted rate ratios, Māori, 1.37; 95% CI, 1.33 to 1.42; Pacific, 1.35; 95% CI, 1.28 to 1.43; South Asian, 1.23; 95% CI, 1.12 to 1.36; Other Asian, 1.31; 95% CI, 1.21 to 1.43; European, 1.29; 95% CI, 1.27 to 1.31). Māori had the highest rate of diabetes and cancer co-occurrence. Rates of GI, endocrine, and obesity-related cancers comprised a bulk of the excess cancers occurring among Māori and Pacific peoples with diabetes. CONCLUSION Our observations reinforce the need for the primordial prevention of risk factors that are shared between diabetes and cancer. Also, the commonality of diabetes and cancer co-occurrence, particularly for Māori, reinforces the need for a multidisciplinary, joined-up approach to the detection and care of both conditions. Given the disproportionate burden of diabetes and those cancers that share risk factors with diabetes, action in these areas is likely to reduce ethnic inequities in outcomes from both conditions.
US Food and Drug Administration Approval Summary: Nivolumab Plus Platinum-Doublet Chemotherapy for the Neoadjuvant Treatment of Patients With Resectable Non–Small-Cell Lung Cancer
Authors: Akinboro Oladimeji , Drezner Nicole , Amatya Anup , Runyan Jin , Fourie-Zirkelbach Jeanne , Zhao Miao , Bi Youwei , Korsah Kwadwo , Mixter Bronwyn , Tang Shenghui , Larkins Erin , Pazdur Richard , Beaver Julia A. , Singh Harpreet 
Published: May 2023

PURPOSE On March 4, 2022, the US Food and Drug Administration (FDA) approved nivolumab plus platinum-doublet chemotherapy for the neoadjuvant treatment of patients with resectable non–small-cell lung cancer (NSCLC). We discuss the FDA's review of the key data and regulatory considerations supporting this approval. PATIENTS AND METHODS The approval was based on the results of CheckMate 816, an international, multiregional, active-controlled trial that randomly assigned 358 patients with resectable NSCLC, stage IB (≥4 cm) to IIIA (N2) per the American Joint Committee on Cancer seventh staging edition to receive either nivolumab plus platinum-doublet or platinum-doublet chemotherapy alone for three cycles before planned surgical resection. The major efficacy end point that supported this approval was event-free survival (EFS). RESULTS At the first planned interim analysis (IA), the hazard ratio (HR) for EFS was 0.63 (95% CI, 0.45 to 0.87; P = .0052; statistical significance boundary = .0262) favoring the nivolumab plus chemotherapy arm; the median EFS was 31.6 months (95% CI, 30.2 to not reached) in the nivolumab plus chemotherapy arm versus 20.8 months (95% CI, 14.0 to 26.7) in the chemotherapy-only arm. At the time of a prespecified IA for overall survival (OS), 26% of patients had died, and the HR for OS was 0.57 (95% CI, 0.38 to 0.87; P = .0079; statistical significance boundary = .0033). Eighty-three percent of patients in the nivolumab-containing arm versus 75% in the chemotherapy-only arm received definitive surgery. CONCLUSION This approval, the first for any regimen for the neoadjuvant treatment of NSCLC in the United States, was supported by a statistically significant and clinically meaningful improvement in EFS with no evidence of detriment in OS or negative impact on patients' receipt and timing of surgery or surgical outcomes.
Turing patterns on coupled phase oscillator chains with localized many-body interactions
Authors: Luo Hao-jie , Xue Yu , Huang Mu-yang , Wang Yi , Zhang Qiang , Zhang Kun 
Published: May 2023

AbstractIn this paper, coupled-phase oscillator chains with localized many-body interactions are studied. Systems have rich patterns such as chimera and twisted states. The coupled-phase oscillator chains have long-range two-body interactions and short-range three-body interactions, which respectively play the role of long-range inhibition of short-range activation, just like inhibitors and activators in traditional reaction-diffusion systems. The role of many-body interaction in the system is studied through the Turing pattern diagram and the critical point of Turing instability is obtained. After Turing instability occurs, the system will flow to twisted states and chimera states. The study indicates that long-range inhibition and short-range activation give an explanation for the formation of such coherent-incoherent modes such as chimera states, and that many-body interactions are good candidates as activators of the system.
Psychopathology in Acromegaly—Real and Perceived
Authors: Pivonello Rosario , Neggers Sebastian J C M M , Imran Syed Ali 
Published: May 2023

Abstract
Acromegaly is a chronic condition caused by the excessive production of growth hormone and is characterized by progressive morphological and systemic complications, as well as increased prevalence of psychopathologies, which markedly affect patients’ quality of life. The advancing multimodal therapies, while significantly improving the morbidity and mortality, have limited impact on psychopathologies, which often persist despite disease remission. The most common psychopathologies in acromegaly include depression, anxiety and affective disorders, together with sexual dysfunction, which may be considered as either a consequence or potentially even a contributory factor to these psychopathologies. Approximately one-third of patients with acromegaly manifest depression, whereas two-thirds of patients display anxiety, with both conditions tending to be more prevalent and severe in younger patients with shorter duration of disease. Apparently, a major impact of psychological discomfort in women compared with men appears to be the fact that women tend to internalize whereas men tend to externalize their distress. Personality disorders also commonly associated with acromegaly, especially due to body image suffering, are linked to sexual dysfunction, which seems to affect women more than men. In summary, psychopathology in acromegaly is a major determinant of the quality of life and a complex array of psychological abnormalities are associated with acromegaly.