bluuebunny/crossref_metadata_2025_split huggingface dataset:
Child‐centredness in paediatric magnetic resonance imaging: Information needs and experiences of children requiring magnetic resonance imaging and their parents
Authors: Inhestern Laura , Herrmann Jochen , Schürmann Jana , Meister Rieke Lisa , Nawka Marie Teresa , Mynarek Martin , Linhart Dieter , Bergelt Corinna 
Published: August 2023

AbstractBackgroundAssessing patient experiences is essential to provide high quality health‐care. The objectives of this study were to examine (1) child‐ and parent‐reported information status before magnetic resonance imaging (MRI), (2) experiences during an MRI and (3) needs and suggestions for improvement.MethodsChildren (≥8 years) and parents answered questionnaires (before and after planned MRI examination) covering mental condition, information status/needs, preparation for MRI, and potential stressors. Before MRI n = 132 accompanying parents and n = 91 children provided data (after MRI: n = 93 parents; n = 71 children). The mean age of the children undergoing MRI was 10.5 years (SD = 4.9). Children had on average seven previous MRIs before our survey (Range: 1–33). Twenty‐three percent of the children were to be sedated during the examination.ResultsParents and children reported low to medium levels of burden, high knowledge and high information status. For the children, most stressful factors during the MRI were boredom and noise. Main information resources were the radiologists or self‐searches. Parents of children with their first MRI reported higher anxiety levels in their children and stated a worse information status (main information source: self‐searches/internet).Parents reported needs regarding organization of the MRI (e.g., reduction of waiting times), age‐appropriate information and communication during the MRI. Children wished to visit the MRI room prior the examination (44%) and to get more information (44%). Children suggested improvements such as better sound quality of films/music, more transparency about the procedure, being in contact with a parent and shorter examinations.ConclusionResults suggest that preparation, information provision and care is perceived positively by families. Needs and suggestions for improvement were, for example, higher transparency of procedures, better communication and reduction of stress. Findings indicate that preparation in routine‐care should follow an individualized child‐focused approach, should focus on families without previous MRIs and should address children with high anxiety levels.
Survival after LDLT in recipients ≥70 years old in the United States. An OPTN/UNOS liver transplant registry analysis
Authors: Robinson Todd , Vargas Paola A. , Oberholzer Jose , Pelletier Shawn , Goldaracena Nicolas 
Published: August 2023

AbstractBackgroundLiving donor liver transplantation (LDLT) in the elderly population is currently not well studied. There are single‐center studies indicating that patient age should not be a barrier to LDLT, with similar outcomes compared to younger recipients.MethodsUsing UNOS/STAR data from 2010 to 2022 we retrospectively analyzed patients ≥70 years old receiving a living donor graft (LDLT ≥70y group) versus a deceased donor graft (DDLT ≥70y group). In addition, we compared recipients ≥70 years old undergoing LDLT versus patients 18–69 years old also undergoing LDLT. Donor and recipient baseline characteristics, as well as postoperative outcomes including graft and patient survival were analyzed and compared between groups.ResultsRecipients in the LDLT ≥70y group showed less disease burden and spent significantly less time on the waitlist when compared to recipients in the DDLT ≥70y group (102 [49–201] days versus 170 [36–336] days) respectively; p = .004. With the exception of a longer length of stay (LOS) in the LDLT ≥70y group (p ≤ .001), postoperative outcomes were comparable with recipients in the DDLT ≥70y group, including similar graft and patient survival rates at 1‐, 3‐, and 5‐years. When compared to younger recipients of a graft from a living donor, patients in the LDLT ≥70y group had similar post‐transplant functional status, re‐transplant rates and similar causes contributing to graft failure. However, significantly lower graft and patient survival rates were observed.ConclusionLDLT for recipients aged 70 or greater represents a faster access to transplantation in a safe and feasible manner when compared to similar‐ aged recipients undergoing DDLT.
White matter hyperintensities in migraine are not mediated by a dysfunction of the glymphatic system—A diffusion tensor imaging magnetic resonance imaging study
Authors: Ornello Raffaele , Bruno Federico , Frattale Ilaria , Curcio Giuseppe , Pistoia Francesca , Splendiani Alessandra , Sacco Simona 
Published: August 2023

AbstractObjectiveWe assessed whether brain magnetic resonance imaging (MRI) markers of glymphatic function are altered in patients with migraine and brain white matter hyperintensities (WMHs).BackgroundThe glymphatic system is responsible for the outflow of waste products from the brain. An impaired glymphatic system has been associated with WMH; however, this impairment has not been shown in patients with migraine.MethodsThe present cross‐sectional study included consecutive patients with migraine from a single tertiary headache center. Glymphatic function was assessed by measuring the diffusion tensor imaging along the perivascular space (DTI‐ALPS) technique, resulting in an index value. WMHs were assessed and quantified by using the Scheltens semi‐quantitative score.ResultsWe included 147 patients (120 women [81.6%]) with a median (interquartile range [IQR]) age of 45 (36–50) years. In all, 74 (50.3%) patients had WMHs. The median (IQR) ALPS index was similar in patients with WMHs compared with those without, at 2.658 (2.332–3.199) versus 2.563 (2.222–3.050) (p = 0.344). The Scheltens score did not correlate with ALPS index (rho = 0.112, p = 0.268).ConclusionsOur results suggest that the presence of WMHs is not associated with an impairment in the glymphatic system in patients with migraine. Although negative and worthy of further confirmation, our finding has implications for the understanding of the nature of WMH in patients with migraine.
Aquafaba from lentils (Lens culinaris) and common beans (Phaseolus vulgaris): a study of cooking variables and drying process on the techno‐functional and microstructural properties
Authors: Golzi María Eugenia , Marchetti Lucas , Lorenzo Gabriel 
Published: August 2023

SummaryThe effect of cooking time and the solid content was analysed in the techno‐functional properties of lentils and common beans aquafaba, and their powders obtained through spray‐drying. Foam drainage kinetic and emulsion destabilisation were successfully modelled showing that lentil aquafaba had better foaming capacity than beans, due to its higher protein content. Moreover, an increase in cooking time results in more liquid incorporated into the foam and a longer lag phase. Bean aquafaba had acceptable emulsifying capacity, attributable to higher soluble carbohydrates. Additionally, microstructure, Fourier Transform Infrared Spectrometry, rehydration capacity, and flowability of aquafaba powders were studied. Microscopy of dried lentil aquafaba showed damaged and collapsed particles, while bean powder consisted of spherical smooth particles. The dominant factor influencing aquafaba functional properties and powder characteristics was the legume type, attributed to their chemical compositions. These findings broaden the insights of alternative sources of aquafaba and enhance the industrial applicability of these residues through highly rehydratable and functional powders.
Thinking with soils: Can urban farms help us heal metabolic rifts in Aotearoa?
Authors: Goburdhone Sasha , Dombroski Kelly 
Published: August 2023

AbstractIn this commentary, we reflect on our work with an urban youth farm where young people (re)connect to the food system. Participating in everyday soil creation and care activities nurtured new relationships with more‐than‐human ecologies and beings at an urban farm called Cultivate Christchurch. In this farm, participants engaged with soils and the process of making and regenerating soil from food waste via composting. We ask whether such activities can begin to help participants thinkwithsoil rather thanaboutit, and to heal the ‘metabolic rift’, the socioecological disconnect from food growing and nutrient cycles.
It would be bad if compatibilism were true; therefore, it isn't
Authors: Todd Patrick 
Published: August 2023

AbstractI want to suggest that it would be bad if compatibilism were true, and that this gives us good reason to think that it isn't. This is, you might think, an outlandish argument, and the considerable burden of this paper is to convince you otherwise. There are two key elements at stake in this argument. The first is that it would be ‐ in a distinctive sense to be explained ‐ bad if compatibilism were true. The thought here is that compatibilism ultimately presents us with a picture on which, in principle, powerful manipulators can effectively guarantee that finite moral agents should become blameworthy. To my mind, this isn't just false ‐ though I think that it is ‐ it is also such that it would be bad (unfortunate, undesirable…) if it were true. The second is that the fact that it would be ‐ in this sense ‐ bad if true gives us reason to think that it isn't. It may be bad that there is no afterlife. But that, in itself, hardly gives us reason to think that there is an afterlife. That is true, but ‐ as others before me have suggested ‐ when the object of the relevant badness is morality itself, the inference seems secure. A more general aim of the paper is to investigate the nature of this very form of argument in itself, and I compare my argument (inter alia) to a recent argument from Sayre–McCord against the possibility of genuine moral dilemmas.
Spatial‐temporal evolution characteristics of residential land prices based on the 2010–2019 land transfer data in China
Authors: Zhang Lu , Lin Xuehan , Chen Yushan , Xiao Yao , Zhang Zuo 
Published: August 2023

AbstractStudying spatial‐temporal change in residential land prices (RLP) can help implement real estate regulations to promote the healthy development of the residential land market. This study applied the urban scaling law to explore the spatial‐temporal pattern of RLP from 2010 to 2019 in China. We found rapid growth in RLP across China from 2010 to 2019, with a growth rate of 179.12%. Among them, the Eastern Region had the highest RLP and growth rates. Furthermore, differences in RLP between large cities and small‐medium cities widened, indicating a trend of the Matthew effect in prefecture‐level cities. Moreover, the scale‐adjusted metropolitan indicator (SAMI) indicated urban agglomerations including Beijing‐Tianjin‐Hebei (BTH), Yangtze River Delta (YRD), Guangdong‐Fujian‐Zhejiang Coastal (GFZ), and Pearl River Delta (PRD) located in the Eastern Region had higher RLP than urban agglomerations with the same population size. In addition, the SAMI also highlighted disproportionately high RLP in some small‐medium cities compared to equivalent cities, warranting regulatory policy attention.
Formate production is dispensable for
Haemophilus ducreyi
virulence in human volunteers
Authors: Brothwell Julie A. , Fortney Kate R. , Williams Jalan S. , Batteiger Teresa A. , Duplantier Rory , Grounds Danielle , Jannasch Amber S. , Katz Barry P. , Spinola Stanley M. 
Published: August 2023

ABSTRACT

Haemophilus ducreyi
is a causative agent of cutaneous ulcers in children who live in the tropics and of the genital ulcer disease chancroid in sexually active persons. In the anaerobic environment of abscesses and ulcers, anaerobic respiration and mixed acid fermentation (MAF) can be used to provide cellular energy. In
Escherichia coli
, MAF produces formate, acetate, lactate, succinate, and ethanol; however, MAF has not been studied in
H. ducreyi
. In human challenge experiments with
H. ducreyi
35000HP, transcripts of the formate transporter FocA and pyruvate formate lyase (PflB) were upregulated in pustules compared to the inocula. We made single and double mutants of
focA
and
pflB
in 35000HP. Growth of 35000HPΔ
focA
was similar to 35000HP, but 35000HPΔ
pflB
and 35000HPΔ
focA-pflB
had growth defects during both aerobic and anaerobic growth. Mutants lacking
pflB
did not secrete formate into the media. However, formate was secreted into the media by 35000HPΔ
focA
, indicating that
H. ducreyi
has alternative formate transporters. The pH of the media during anaerobic growth decreased for 35000HP and 35000HPΔ
focA
, but not for 35000HPΔ
pflB
or 35000HPΔ
focA-pflB
, indicating that
pflB
is the main contributor to media acidification during anaerobic growth. We tested whether formate production and transport were required for virulence in seven human volunteers in a mutant versus parent trial between 35000HPΔ
focA-pflB
and 35000HP. The pustule formation rate was similar for 35000HP (42.9%)- and 35000HPΔ
focA-pflB
(62%)-inoculated sites. Although formate production occurs during
in vitro
growth and
focA-pflB
transcripts are upregulated during human infection,
focA
and
pflB
are not required for virulence in humans.
i-Sample: Augment Domain Adversarial Adaptation Models for WiFi-based HAR
Authors: Zhou Zhipeng , Wang Feng , Gong Wei 
Published: August 2023

Recently, using deep learning to achieve WiFi-based human activity recognition (HAR) has drawn significant attention. While capable of achieving accurate identification in a single domain (i.e., training and testing in the same consistent WiFi environment), it would become extremely tough when WiFi environments change significantly. As such, domain adversarial neural networks-based approaches have been proposed to handle such diversities across domains, yet often found to share the same limitation in practice: the imbalance between high-capacity of feature extractors and data insufficiency of source domains.
This article proposes i-Sample, an intermediate sample generation-based framework, striving to tackle this issue for WiFi-based HAR. i-Sample is mainly designed as two-stage training, where four data augmentation operations are proposed to train a coarse domain-invariant feature extractor in the first stage. In the second stage, we leverage the gradients of classification error to generate intermediate samples to refine the classifiers together with original samples, making i-Sample also capable to be integrated into most domain adversarial adaptation methods without neural network modification. We have implemented a prototype system to evaluate i-Sample, which shows that i-Sample can effectively augment the performance of nowadays mainstream domain adversarial adaptation models for WiFi-based HAR, especially when source domain data is insufficient.
La « pensée plastique » de Jean-Marie Floch: pour une sémio-anthropologie des « mondes imagés »
Authors: Chatenet Ludovic 
Published: August 2023

Notre article, hommage à Jean-Marie Floch, envisage de discuter la sémiotique plastique, associée aux systèmes semi-symboliques (Floch 1985, 1995) en la considérant comme fondatrice d’une approche sémio-anthropologique susceptible de prendre en charge la culture au travers de l’ensemble de ses manifestations. En remettant la sémitoque plastique en perspective avec son contexte d’apparition, dans la sémiotique greimassienne, puis avec les travaux de Lévi-Strauss qui l’ont profondément inspiré, nous entendons plus particulièrement réévaluer ses principes pour une étude des « mondes imagés ». Puisque la sémiotique plastique rend compte de la manière dont les humains construisent non seulement des « micro-scènes imagées », mais aussi des objets qui les mettent en relation avec le monde, nous affirmerons sa pertinence pour étudier, et questionner, les nouveaux objets virtuels tels que les jeux vidéo.
The conditions of motivation of signs according to the semi-symbolic system
Authors: Migliore Tiziana 
Published: August 2023

Une étude attentive des œuvres de Floch peut contribuer à préciser et à mettre à jour la question de la motivation des signes. C’est le but de notre article, de comprendre mieux le caractère fondé de la relation entre le signifiant et le signifié à travers la catégorie sémiotique que Floch a sondé, expliqué et appliqué à maintes reprises et dont il a été le promulgateur majeur : le semi-symbolique. Notre hypothèse est que les refléxions théoriques et les analyses empiriques flochiennes impliquent une conception épistemique de la pensée corrélative et contrastive. Le semi-symbolique dépasse l’occurrence du décodage et de l’encodage particuliers d’un texte donné pour s’élever au rang d’un modèle structurant de la logique du sensible, adroit à produire des effets de sens « vérité », à gérer le jeu de la vérité, entre la dimension de la manifestation (paraître/non-paraître) et celle de l’immanence (être/non-être). Après avoir relit et examiné quelques passages plus relevants de Floch à ce propos, on reviendra sur le semi-symbolique comme relation motivée et on démontrerà la fecondité de cet outil même face à des grandes banques de données.
Primary Aldosteronism in Chronic Kidney Disease: Blood Pressure Control and Kidney and Cardiovascular Outcomes After Surgical Versus Medical Management
Authors: Cohen Debbie L. , Wachtel Heather , Vaidya Anand , Hundemer Gregory L. , Tezuka Yuta , Davio Angela , Turcu Adina F. , Cohen Jordana B. 
Published: August 2023

Background:
Diagnosis and treatment of primary aldosteronism (PA) in chronic kidney disease (CKD) may be deferred due to limited evidence supporting safety and efficacy of treatment. Our goal was to assess clinical outcomes in patients with PA and CKD who received surgical or medical management.

Methods:
We conducted a multicenter, retrospective cohort study of patients with PA and CKD who underwent adrenal vein sampling from 2009-2019. We characterized clinical outcomes and evaluated differences by surgical versus medical management. Primary outcomes were systolic blood pressure and number of antihypertensive medications. Secondary outcomes were diastolic blood pressure, serum potassium, estimated glomerular filtration rate (eGFR), and kidney and cardiovascular events. Analyses were adjusted for age, sex, race, cardiovascular disease, diabetes, and eGFR.

Results:

Of 239 participants with PA and CKD, 158 (66%) underwent adrenalectomy, and 81 (34%) were treated medically. Mean age was 57±10 years, 67% were female, mean eGFR was 45±12 mL/min per 1.73 m
2
, and 49% were on potassium supplementation. At 5 years, mean blood pressure decreased from 149±22/85±14 to 131±28/78±16 mm Hg and mean number of antihypertensive medications decreased from 4.0±1.5 to 2.4±1.4. Adrenalectomy, compared to medical management, was associated with similar systolic blood pressure (−0.90 mm Hg [95% CI, −6.99 to 5.07]) but fewer medications (1.7 [95% CI, −2.24 to −1.10]), and no difference in potassium levels or kidney or cardiovascular outcomes.

Conclusions:
Patients with PA and CKD are likely to benefit from either surgical adrenalectomy or medical management. Detection and treatment of PA may help to reduce blood pressure and medication burden in patients with CKD.
Impact of Carotid Stent Design on Embolic Filter Debris Load During Carotid Artery Stenting
Authors: Squizzato Francesco , Piazza Michele , Forcella Edoardo , Colacchio Elda Chiara , Fedrigo Marny , Angelini Annalisa , Grego Franco , Antonello Michele 
Published: August 2023

BACKGROUND:
The carotid stent design may influence the risk of embolization during carotid artery stenting. The aim of the study was to assess this risk by comparing the quantity of embolized material captured by filters during carotid artery stenting, using different stent designs.

METHODS:
We conducted a single-center retrospective study of patients undergoing carotid artery stenting for asymptomatic carotid stenosis >70% (2010–2022) in a tertiary academic hospital (Padua University Hospital, Italy). Carotid stents were classified according to their design as open-cell (OCS), closed-cell (CCS), or micromesh stents (MMS). A distal filter protection was used in all patients, and the amount of captured embolized particles was semiautomatically analyzed using a dedicated software (Image-Pro Plus, Media Cybernetics). Primary end point was embolic filter debris (EFD) load, defined as the ratio of the filter area covered by particulate material to the total filter area. Secondary end points were 30 days major stroke and death.

RESULTS:

Four-hundred-eighty-one carotid artery stentings were included; 171 (35%) using an OCS, 68 (14%) a CCS, and 242 (50%) a MMS. Thirty-days mortality was 0.2% (n=1) and major stroke rate was 0.2% (
P
=0.987). Filters of patients receiving MMS were more likely to be free from embolized material (OCS, 30%; CCS, 13%; MMS, 41%;
P
<0.001) and had a lower EFD load (OCS, 9.1±14.5%; CCS, 7.9±14.0%; MMS, 5.0±9.1%;
P
<0.001) compared with other stent designs. After stratification by plaque characteristics, MMS had a lower EFD load in cases of hypoechogenic plaque (OCS, 13.4±9.9%; CCS, 10.9±8.7%; MMS, 6.5±13.1%;
P
<0.001), plaque length>15 mm (OC, 10.2±15.3; CC, 8.6±12.4; MM, 8.2±13.6;
P
<0.001), and preoperative ipsilateral asymptomatic ischemic cerebral lesion (OCS, 12.9±16.8%; CCS, 8.7±19.5%; MMS, 5.4±9.7%;
P
<0.001). After multivariate linear regression, use of MMS was associated with lower EFD load (
P
=0.038).

CONCLUSIONS:
The use of MMS seems to be associated with a lower embolization rate and EFD load, especially in hypoechogenic and long plaques and in patients with a preoperative evidence of asymptomatic ischemic cerebral lesion.
“Book Zero” through the Years
Authors: Meletiadis Vasileios M. 
Published: August 2023

Abstract
This paper presents an analysis of the first two editions of Peter Carroll’s Liber Null (1978, 1981). Along with Ray Sherwin’s The Book of Results (1979, 1980, 1981), they shape the earliest corpus of chaos magic literature. Often overlooked due to their rarity and the availability of the mainstream 1987 edition of Liber Null, these two, the so-called white and red editions, offer a peak into the early years of the chaos magic current and the formation of Carroll’s ideas. The white edition in particular contains concepts and terminology that are either nonexistent or significantly altered in the later editions. The paper opens with a history of these texts, followed by some comments on their materiality. The main focus, however, is to closely analyse the 1978 edition and to consider the significance of textual variations in later editions.