bluuebunny/crossref_metadata_2025_split huggingface dataset:
Two decades of nonfatal injury data: a scoping review of the National Electronic Injury Surveillance System-All Injury Program, 2001–2021
Authors: Navon Livia , Chen Li Hui , Cowhig Mary , Wolkin Amy Funk 
Published: September 2023

Abstract
Background
Injury is a leading cause of preventable morbidity and mortality in the USA. Ongoing surveillance is needed to understand changing injury patterns to effectively target prevention efforts. Launched jointly in 2000 by the Consumer Product Safety Commission (CPSC) and the Centers for Disease Control and Prevention (CDC), the National Electronic Injury Surveillance System-All Injury Program (NEISS-AIP) provides national-level estimates of US emergency department visits for nonfatal injuries. A scoping review of peer-reviewed articles was conducted to characterize how NEISS-AIP data have been used for injury surveillance in the USA.

Main Body
This review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Three bibliographic databases (PubMed, Scopus, and Google Scholar) were systematically searched for English language peer-reviewed articles that used NEISS-AIP data as the primary data source during 2001–2021. Key article characteristics from included articles were abstracted to generate descriptive summary statistics to understand the use and limitations of NEISS-AIP for injury surveillance. Database queries returned 6944 citations; 594 citations were manually reviewed, and 167 non-duplicate journal articles were identified. An average of 8.0 articles (range: 1–14) were published annually during 2001–2021. Articles appeared in 72 different journals representing a diverse audience with the majority of articles written by CDC authors. Starting in 2013, a higher proportion of articles were published by non-CDC authors. The largest number of articles examined injury among all age groups (n = 71); however, the pediatric population was the specific age group of greatest interest (n = 48), followed by older adults (n = 23). Falls (n = 20) and motor-vehicle-related injuries (n = 10) were the most studied injury mechanisms. The most commonly identified limitation identified by authors of reviewed articles was that NEISS-AIP only produces national estimates and therefore, cannot be used for state- or county-level injury surveillance (n = 38).

Conclusions
NEISS-AIP has contributed to nonfatal injury surveillance in the USA. CDC and CPSC continue to work together to expand and enhance NEISS-AIP data collection. Researchers are encouraged to continue using this publicly available dataset for injury surveillance.
Reproductive studies on the carpet clam Paphia textile (Paratapes textilis) (Gmelin 1791) (Family: Veneridae): a guide of aquaculture management along the Egyptian coasts of the Red Sea and Suez Canal
Authors: Farghaly Marwa I. , Ali Tamer El-Sayed , Mitwally Hanan M. , Abdel Razek Fatma A. 
Published: September 2023

Abstract
Background
Most aquatic biota's reproductive biology and life cycle are essential to the sustainable management and development of coastal ecosystems and aquaculture. The bivalve Paphia textile (Gmelin 1791), also known as Paratapes textilis, has an economic value in Indo-Pacific waters, including the Red Sea and the Suez Canal lakes, the Egyptian coasts. However, P. textile suffers from extensive fishing and exploitation.

Aim
The present work aims to study the Paphia textile's reproductive cycle on the Egyptian coasts of the Red Sea for the first time. It helps to manage and develop the coastal ecosystems and aquaculture.

Methodology
Samples were collected monthly from two saline lakes in the Suez Gulf from December 2019 to November 2020. As part of the comprehensive research study, sex ratio, condition index, sexuality, histological analysis of gonads, shell size, and gonad index were used to investigate the reproductive cycle.

Results
The results reveal a male-biased sex ratio, possibly due to anthropogenic stressors. The Paphia textile is dioecious. No hermaphrodite cases were observed in the studied specimens. The condition index in winter and spring indicates periods dominated by mature individuals. Five reproductive maturity stages were assigned for both P. textile males and females. Due to the simultaneous development of several developmental stages monthly throughout the sampling year, warm water may be responsible for non-sequential gametogenic cycles. As measured environmental parameters correlate with maturity stages, temperature, salinity, and chlorophyll a play important role in gonad growth. The size at first sexual maturity at which 50% of the Paphia textile population reached maturity ranged from 28.60 to 31.50 mm for females, and between 31.70 and 34.10 mm for males. As the gonad index increases during the ripe stages, this index decreases during the resting, spawning, and spent phases.

Conclusions
The findings suggest the most suitable temperature for aquaculture spawning is between 20 °C and 30 °C in subtropical waters. Fishing should generally be prohibited at sizes less than 28.60 mm for better management and sustainability of this valuable aquatic resource on the Egyptian coasts of the Red Sea.
Inclusive approaches to involvement of community groups in health research: the co-produced CHICO guidance
Authors: Jameson Catherine , Haq Zehra , Musse Samira , Kosar Zahra , Watson Gloria , Wylde Vikki 
Published: September 2023

Abstract
Background
Racially marginalised groups are underserved in healthcare and underrepresented in health research. Patient and public involvement and engagement (PPIE) is established as the method to ensure equity in health research. However, methods traditionally employed in PPIE can lead to the exclusion of some communities and exacerbation of existing inequalities, highlighting the need to develop inclusive processes for more inclusive community involvement in health research. We aimed to produce guidance to promote good practice for inclusive involvement of racially marginalised community groups in health research via public and community involvement and engagement.

Methods
The CHecklist for Inclusive COmmunity involvement in health research (CHICO) was co-produced by researchers and three Bristol-based community organisations: Dhek Bhal, My Friday Coffee Morning—Barton Hill, and Malcolm X Elders. After initial conversations and link building with community leaders to develop relationships, researchers attended at least three meetings with each community group to discuss preferred approaches to involvement. Each community group had a different format, and discussions were open and tailored to fit the groups preferences. The meetings were held in the community groups’ usual meeting venue. Notes from meetings were reviewed by researchers to identify key themes, which were used to inform the creation of a draft illustration which was then taken back to the community groups for refinement and used to inform the development of written guidance and the final illustration.

Results
Checklist items were structured into three stages: (1) building relationships, (2) reciprocal relationships and (3) practicalities. Stage 1 highlights the importance of building trust with the community group over time through regular visits to community venues and talking to people informally to understand the history of the group, their preferences and needs, and topics that are likely to be of interest to them. Stage 2 focusses on maintaining a reciprocal relationship and understanding how to best to give back to the community. Stage 3 provides guidance on the practicalities of designing and running inclusive community-based involvement activities, including consideration of the venue, format, communication-style, language requirements, social activities, and provision of food.

Conclusions
Our co-produced checklist can guide researchers in how to involve people from different ethnicities in health research that is relevant to their community.
Differences in decisions affected by cognitive biases: examining human values, need for cognition, and numeracy
Authors: Kakinohana Regis K. , Pilati Ronaldo 
Published: September 2023

AbstractA better understanding of factors that can affect preferences and choices may contribute to more accurate decision-making. Several studies have investigated the effects of cognitive biases on decision-making and their relationship with cognitive abilities and thinking dispositions. While studies on behaviour, attitude, personality, and health worries have examined their relationship with human values, research on cognitive bias has not investigated its relationship to individual differences in human values. The purpose of this study was to explore individual differences in biased choices, examining the relationships of the human values self-direction, conformity, power, and universalism with the anchoring effect, the framing effect, the certainty effect, and the outcome bias, as well as the mediation of need for cognition and the moderation of numeracy in these relationships. We measured individual differences and within-participant effects with an online questionnaire completed by 409 Brazilian participants, with an age range from 18 to 80 years, 56.7% female, and 43.3% male. The cognitive biases studied consistently influenced choices and preferences. However, the biases showed distinct relationships with the individual differences investigated, indicating the involvement of diverse psychological mechanisms. For example, people who value more self-direction were less affected only by anchoring. Hence, people more susceptible to one bias were not similarly susceptible to another. This can help in research on how to weaken or strengthen cognitive biases and heuristics.
Viewpoint: Difficult-to-treat depression versus treatment-resistant depression: A new integrative perspective for managing depression
Authors: Paganin Walter 
Published: September 2023

Abstract
In the STAR*D study, the efficacy of treatments for major depression was examined. It was found that, while many responded to the initial antidepressant treatment, only 30% of participants achieved complete remission. Concerning treatment resistance in depression, there is a recent distinction emerging between treatment-resistant depression (TRD) and difficult-to-treat depression (DTD). Historically, TRD and DTD have been conflated, but it is essential to recognize them as separate entities. While TRD is characterized by a patient’s inadequate response to two or more consecutive antidepressant treatments given for an adequate duration and dosage without achieving acceptable therapeutic effects, DTD describes a clinical category where patients do not achieve full symptom control despite various therapeutic approaches. The recent shift in perspective proposes a more integrated approach for DTD, encompassing psychosocial, biological, and interactive factors. This multifactorial model calls for a multidisciplinary therapeutic intervention, not restricted to pharmacological treatments but also including psychotherapy, neurostimulation, and social interventions. Informing professionals and the general public about the significance of this new approach could mitigate the stigma associated with depression and enhance the quality of care. The future challenge will involve a deeper clinical understanding of DTD and its optimal management by refining available treatments.
Single-cell transcriptomics identifies new blood cell populations in Drosophila released at the onset of metamorphosis
Authors: Hirschhäuser Alexander , Molitor Darius , Salinas Gabriela , Großhans Jörg , Rust Katja , Bogdan Sven 
Published: September 2023

ABSTRACT
Drosophila blood cells called hemocytes form an efficient barrier against infections and tissue damage. During metamorphosis, hemocytes undergo tremendous changes in their shape and behavior, preparing them for tissue clearance. Yet, the diversity and functional plasticity of pupal blood cells have not been explored. Here, we combine single-cell transcriptomics and high-resolution microscopy to dissect the heterogeneity and plasticity of pupal hemocytes. We identified undifferentiated and specified hemocytes with different molecular signatures associated with distinct functions such as antimicrobial, antifungal immune defense, cell adhesion or secretion. Strikingly, we identified a highly migratory and immune-responsive pupal cell population expressing typical markers of the posterior signaling center (PSC), which is known to be an important niche in the larval lymph gland. PSC-like cells become restricted to the abdominal segments and are morphologically very distinct from typical Hemolectin (Hml)-positive plasmatocytes. G-TRACE lineage experiments further suggest that PSC-like cells can transdifferentiate to lamellocytes triggered by parasitoid wasp infestation. In summary, we present the first molecular description of pupal Drosophila blood cells, providing insights into blood cell functional diversification and plasticity during pupal metamorphosis.
Surf4 collaborates with derlin-2 and derlin-1 to mediate cyclooxygenase-2 translocation to the cytosol for degradation
Authors: Chen Shu-Fen , Wu Chun-Hu , Lee Yen-Ming , Tam Kabik , Liou Jun-Yang , Shyue Song-Kun 
Published: September 2023

ABSTRACT
Derlin family members participate in the retrotranslocation of endoplasmic reticulum (ER) lumen proteins to the cytosol for ER-associated degradation (ERAD); however, the proteins facilitating this retrotranslocation remain to be explored. Using CRISPR library screening, we have found that derlin-2 and surfeit locus protein 4 (Surf4) are candidates to facilitate degradation of cyclooxygenase-2 (COX-2, also known as PTGS2). Our results show that derlin-2 acts upstream of derlin-1 and that Surf4 acts downstream of derlin-2 and derlin-1 to facilitate COX-2 degradation. Knockdown of derlin-2 or Surf4 impedes the ubiquitylation of COX-2 and the interaction of COX-2 with caveolin-1 (Cav-1) and p97 (also known as VCP) in the cytosol. Additionally, COX-2 degradation is N-glycosylation dependent. Although derlin-2 facilitates degradation of N-glycosylated COX-2, the interaction between derlin-2 and COX-2 is independent of COX-2 N-glycosylation. Derlin-1, Surf4 and p97 preferentially interact with non-glycosylated COX-2, whereas Cav-1 preferentially interacts with N-glycosylated COX-2, regardless of the N-glycosylation pattern. Collectively, our results reveal that Surf4 collaborates with derlin-2 and derlin-1 to mediate COX-2 translocation from the ER lumen to the cytosol. The derlin-2–derlin-1–Surf4–Cav-1 machinery might represent a unique pathway to accelerate COX-2 degradation in ERAD.
Patterns of fatty acid usage in two nocturnal insectivores: the Mediterranean house gecko (Hemidactylus turcicus) and the Etruscan pygmy shrew (Suncus etruscus)
Authors: Dubiner Shahar , Kashi Amit , Drabkin Ariel , Blinder Pablo , Levin Eran 
Published: September 2023

ABSTRACT
Dietary fatty acids (FAs) have been demonstrated to be differentially stored or used as a metabolic fuel, depending on carbon chain length or saturation level. However, intestinal absorption also differs among FAs, potentially biasing conclusions on functional differences and their subsequent implications. We tested dietary FA usage in a nocturnal insectivorous reptile and a nocturnal insectivorous mammal of similar size: the gecko Hemidactylus turcicus and the shrew Suncus etruscus. We compared the relative presence of 13C isotopes in breath and feces following ingestion of three isotopically enriched fatty acids: linoleic acid (a polyunsaturated FA), oleic acid (monounsaturated) and palmitic acid (saturated). Both species oxidized linoleic and oleic acids at much higher levels than palmitic acid. Egestion of palmitic acid in feces was much higher than that of linoleic and oleic acids. The major difference between geckos and shrews was that the latter digested fatty acids much faster, which was best explained by the difference in the metabolic rates of the species. Circadian differences were evident for gecko metabolic and FA oxidation rates, peaking at night; for shrews, peak oxidation was achieved faster at night but rates did not differ. Our study is among the first to integrate oxidation and absorption patterns, as well as metabolic rates and their rhythms, providing important insights into the utilization of different dietary FAs in different species.
Risk factors for 6-to-24-month-old toddlers in district of Tanara: survey of hygiene sectors, worm infection, and complementary feeding to reduce stunting
Authors: Nugrohowati Nunuk , Purwani Luh Eka , Kristanti Melly , Simanjuntak Kristina , Nurcita Boenga , Wahyuni Yosha Putri , Heryani Monalisa 
Published: September 2023

Background: Children in Indonesia still struggle against being stunted, wasted, and underweight. In 2018, 30.8 % of children under five years old were stunted, in 2022, it had decreased to 21.6%. The stunting rate in Pandeglang Regency in 2019 was 41.6%, whereas the incidence in Banten Province was 24.1%. This study aims to determine factors that influence the occurrence of stunting in children aged 6–24 months in Tanara District, Serang Regency, Indonesia. Methods: A cross-sectional approach was used on a sample consisting of 40 mothers with children aged 6–24 months in September 2020, selected using consecutive sampling from nine subdistricts. Results: Of the total respondents, 21 (52.5%) have stunted children aged 6–24 months, 28 (70%) children had completed exclusive breastfeeding, and 65% had poor knowledge of complementary feeding. Findings reveal a relationship between the incidence of stunting and the history of infectious disease, a lack of complementary feeding knowledge, and a lack of a healthy life attitude. Conclusions: The most influential factor in stunting in children aged 6–24 months was the history of infectious disease and the attitude toward a healthy life. A lower history of infectious disease in children under five will give a low incidence of stunting; conversely, a higher attitude toward healthy living lowers the incidence of stunting. In this study, the specific nutrition intervention programs required are learning classes for mothers, whether they are mothers of infants/toddlers or pregnant women. Moreover, the improvement of sensitive intervention programs for environmental hygiene needs to be encouraged, which is conducted by the local government and the community. The need to integrate nutrition-specific and sensitive interventions into efforts to improve children’s health should be met so that the handling of nutritional problems can be sustainable.
Ownership Concentration and Firm Value: New Evidence from Owner Stakes in IPOs
Authors: Larrain Borja , Roosenboom Peter , Sertsios Giorgo , Urzúa Francisco 
Published: September 2023

We study the relationship between ownership concentration and firm value using hand-collected data on the stakes of owner–managers before and after initial public offerings (IPOs). We instrument for the reduction in stake using market returns shortly before IPOs. Short-run market returns are plausible instruments because owners engage in market timing by selling more when prior returns are high, but high short-run returns are unlikely to directly affect firm value years after the IPO. As predicted by agency theory, a large reduction in ownership concentration at the IPO is negatively related to valuation. Future asset growth is low when owners have low stakes. This paper was accepted by Victoria Ivashina, finance. Funding: B. Larrain acknowledges funding from ANID/CONICYT Proyecto FONDECYT Regular [Grant 1180593]. Supplemental Material: The online appendix and data are available at https://doi.org/10.1287/mnsc.2021.01039 .
Gift Contagion in Online Groups: Evidence from Virtual Red Packets
Authors: Yuan Yuan , Liu Tracy Xiao , Tan Chenhao , Chen Qian , Pentland Alex Sandy , Tang Jie 
Published: September 2023

Gifts are important instruments for forming bonds in interpersonal relationships. Our study analyzes the phenomenon of gift contagion in online groups. Gift contagion encourages social bonds by prompting further gifts; it may also promote group interaction and solidarity. Using data on 36 million online red packet gifts on a large social site in East Asia, we leverage a natural experimental design to identify the social contagion of gift giving in online groups. Our natural experiment is enabled by the randomization of the gift amount allocation algorithm on the platform, which addresses the common challenge of causal identification in observational data. Our study provides evidence of gift contagion: On average, receiving one additional dollar causes a recipient to send 18 cents back to the group within the subsequent 24 hours. Decomposing this effect, we find that it is mainly driven by the extensive margin: more recipients are triggered to send red packets. Moreover, we find that this effect is stronger for “luckiest draw” recipients, suggesting the presence of a group norm regarding the next red packet sender. Finally, we investigate the moderating effects of group- and individual-level social network characteristics on gift contagion as well as the causal impact of receiving gifts on group network structure. Our study has implications for promoting group dynamics and designing marketing strategies for product adoption. This paper was accepted by Axel Ockenfels, behavioral economics and decision analysis. Funding: T. Liu was supported by Natural Science Foundation of China [Grant 72222005] and Tsinghua University [Grant 2022Z04W01032]. J. Tang was supported by Natural Science Foundation of China for Distinguished Young Scholar [Grant 61825602]. Supplemental Material: The data files and online appendices are available at https://doi.org/10.1287/mnsc.2023.4906 .
Stochastic Subgradient Descent Escapes Active Strict Saddles on Weakly Convex Functions
Authors: Bianchi Pascal , Hachem Walid , Schechtman Sholom 
Published: September 2023

In nonsmooth stochastic optimization, we establish the nonconvergence of the stochastic subgradient descent (SGD) to the critical points recently called active strict saddles by Davis and Drusvyatskiy. Such points lie on a manifold M, where the function f has a direction of second-order negative curvature. Off this manifold, the norm of the Clarke subdifferential of f is lower-bounded. We require two conditions on f. The first assumption is a Verdier stratification condition, which is a refinement of the popular Whitney stratification. It allows us to establish a strengthened version of the projection formula of Bolte et al. for Whitney stratifiable functions and which is of independent interest. The second assumption, termed the angle condition, allows us to control the distance of the iterates to M. When f is weakly convex, our assumptions are generic. Consequently, generically, in the class of definable weakly convex functions, SGD converges to a local minimizer. Funding: The work of Sholom Schechtman was supported by “Région Ile-de-France”.