bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH HEALTH EDUCATION SEKSUALITAS TERHADAP PENGETAHUAN BAHAYA SEKS DENGAN METODE STRATAGEM PADA REMAJA PUTRI USIA 15-16 TAHUN DI PP. AN-NASHRIYAH JOMBANG
Authors: Purniasari Lia , Kusyani Asri , Putri S Shelfi D.R 
Published: January 2023

Pendahuluan : Pada masa remaja terjadi berbagai macam perubahan yang cukup penting baik secara fisik dan psikologis, ketidakseiapan remaja dalam menghadapai perubahan tersebut dapat menimbulkan seksualitas bebas, kenakalan remaja, kehamilan yang tidak diinginkan, salah satu penyebab terjadinya hal ini adalah kurangnya pengetahuan terhadap bahaya seks. Tujuan : Tujuan penelitian ini untuk menganalisis pengaruh health education seksualitas dengan metode stratagem terhadap pengetahuan bahaya sek pada remaja putri usia 15-16 tahun. Metode : Rencana penelitian ini menggunakan quasi eksperimen dengan pendekatan eksperimen sebelum dan sesudah. Populasi penelitian sebanyak 28 samplel dengan cara total sampling. Pengumpulan data dilakukan dengan menggunakan kuesioner sebelum dan sesudah diberikan health education dengan metode stratagem. Cara menganalisisnya adalah menggunakan uji wilcoxon signed ranks test didapatkan nilai signifikan p<0,05. Hasil : Hasil penelitian pengaruh pengetahuan terhadap bahaya seksualitas dari sebelum dan sesudah diberikan health education seksualitas dengan metode stratagem didapatkan nilai signifikan (p=,000), sehingga H1 diterima. Didapatkan dari 28 responden sebelum diberikan health education sebagian besar 15 responden memiliki tingkat pengetahuan cukup (53,6%) dan setelah diberikan health education seksualitas hampir seluruhnya 27 responden memiliki tingkat pengetahuan baik (96,4%). Kesimpulan : Kesimpulan penelitian ini adalah ada pengaruh health education seksualitas terhadap pengetahuan bahaya seks pada remaja putri usia 15-16 tahun di PP. An-Nashriyah Jombang. Saran : Remaja perlu mendapatkan health education seksualitas guna untuk meningkatkan pengetahuan bahaya seks dan pencegahan-pencegahan terhadap seksualitas bebas.
PENGARUH PSIKOEDUKASI AUDIOVISUAL TERHADAP BELIEF REMAJA DALAM PENCEGAHAN DRUG ABUSE DI KABUPATEN TUBAN
Authors: Jannah Roudlotul , Nugraheni Wahyuningsih Triana , Ningsih Wahyu Tri 
Published: January 2023

Pendahuluan : Survey United Nations Office on Drug and Crime (2018), menyebutkan sebanyak 275 juta penduduk di dunia atau 5,6% penduduk dunia (usia 15-64 tahun) pernah mengonsumsi narkoba. Kabupaten Tuban mengalami peningkatan signifikan terkait kasus narkoba. Data Polres Tuban, mencatat peningkatan kasus hingga 173,68% jika dibandingkan dengan kasus serupa pada tahun 2017. Tercatat tahun 2018, jumlah kasus narkoba yang ditangani oleh Sat Resnarkoba Polres Tuban ada sebanyak 52 kasus. Metode : Penelitian kuantitatif yang menggunakan desain quasy experiment dengan pre-post control group design. Penelitian ini bertujuan untuk membuktikan hubungan sebab akibat dengan pemberian intervensi psikoedukasi audiovisual. Populasi penelitian adalah seluruh siswa di SMPN 2 Tuban sebanyak 761 siswa, sampel yang digunakan masing-masing kelompok 20 orang dengan tehnik simple random sampling. Kelompok intervensi diberikan psikoedukasi audiovisual dan kelompok kontrol dengan leaflet. Data dikumpulkan dengan kuesioner. Analisis data yang digunakan adalah uji Wilcoxon Sign Rank Test dan uji Mann Whitney. Hasil : menunjukkan bahwa rata-rata nilai post test untuk belief remaja kelompok intervensi (91,95) lebih besar daripada kelompok kontrol (87,10) dengan selisih 4,82, ini menunjukkan metode psikoedukasi audiovisual mempunyai hasil yang lebih baik dalam meningkatkan belief remaja dalam upaya pencegahan drug abuse. Kesimpulan : Pemberian edukasi dengan multi media seperti audiovisual penting dilakukan untuk peningkatan belief remaja dalam pembentukan sikap yang positif untuk pencegahan drug abuse.
PENGARUH TERAPI RELAKSASI OTOT PROGRESIF DALAM MENURUNKAN TEKANAN DARAH PENDERITA HIPERTENSI
Authors: Yudanari Yunita Galih , Puspitasari Odilia 
Published: January 2023

APendahuluan : Hipertensi menjadi penyakit yang paling mematikan di Negara maju maupun berkembang selama lebih dari delapan dekade terakhir. Hipertensi di Negara Indonesia menjadi penyebab kematian ketiga selain stroke dan tuberculosis. Penanganan hipertensi dilakukan dengan upaya penurunan tekanan darah dengan perangsangan aktivitas saraf simpatis dan parasimpatis dengan teknik relaksasi otot progresif.Tujuan: Tujuan penelitian ini adalah mengetahui pengaruh relaksasi otot progresif terhadap penurunan tekanan darah penderita hipertensi di desa Asinan Kelurahan Bawen Kecamatan Bawen Kabupaten Semarang.Metode: Metode dalam penelitian menggunakan quasi eksperimen dengan desain twogroup pre-post test. Teknik pengambilan data dengan purposive sampling dan Analisis data menggunakan uji dependent dan independent T Test.Hasil penelitian menunjukkan terdapat penurunan rata-rata tekanan darah sistolik sebelum dan setelah diberikan terapi relaksasi otot progresif dari 161.06 mmHg menjadi 138,35 mmHg dan rata-rata tekanan diastolic dari 94.35 mmHg menjadi 85.76 mmHg, hasil uji beda pengaruh menggunakan Independent T Test diperoleh tekanan darah sistolik p=0,001<?=0,05 dan tekanan darah diastolik p = 0,009 <?=0,05. Hal ini dapat disimpulkan ada pengaruh terapi otot progresif terhadap tekanan darah lansia penderita hipertensi di desa asinan kelurahan bawen kecamatan bawen kabupaten semarang
AKTIVITAS FISIK DAN KORELASINYA DENGAN KUALITAS HIDUP PADA PASIEN HIPERTENSI
Authors: Lainsamputty Ferdy , Ruku Denny Maurits , Susanti Ni Made Dewi , Amir Yuliyanti 
Published: January 2023

Pendahuluan: Hipertensi merupakan penyakit yang berkontribusi terhadap mortalitas tinggi setiap tahun. Di Indonesia, hipertensi termasuk dalam penyakit yang dominan diderita. Kurangnya aktivitas fisik beresiko meningkatkan terjadinya hipertensi. Faktor ini juga sangat berpotensi mengganggu kualitas hidup penderitanya. Penelitan ini bertujuan untuk mengidentifikasi korelasi antara aktivitas fisik dan kualitas hidup, serta domain keduanya pada pasien hipertensi Metode: Penelitian ini berjenis deskriptif korelasi dengan pendekatan potong lintang menggunakan 146 sampel yang direkrut dengan teknik purposive sampling dari dua rumah sakit umum di Sulawesi Tengah. Kuesioner yang digunakan yaitu International Physical Activity Questionnaeire (IPAQ) dan World Health Organization Quality of Life-BREF (WHOQOL-BREF). Statistik deskriptif (frekuensi, presentasi, rata-rata, standar deviasi, range) dan analisa bivariat (Mann-Whitney, Kruskal-Wallis, Spearman Rank) digunakan mencari hubungan antarvariabel. Statistik deskriptif dan analisa bivariat difungsikan dalam mendeskripsikan dan mengidentifikasi hubungan antar variabel. Hasil: Aktivitas fisik berkorelasi signifikan dengan domain kualitas hidup fisik, psikologis, dan sosial (r = 0,26 - 0,34; p < 0,01). Kesimpulan: Pasien hipertensi yang beraktivitas fisik secara optimal, juga mempunyai persepsi yang baik terhadap status kesehatan fisik, psikologis, dan sosialnya.

Introduction: Hypertension contributes to a high mortality anually. In Indonesia, hypertension is common among the population. Lack of physical activity may increase the risk of hypertension. This factor is also very influential on patient’s quality of life.. This study aimed to determine the correlation between physical activity and quality of life (QoL), as well as their domains among hypertensive patients. Methods: This was a descriptive correlational study with cross-sectional approach using 146 samples recruited by purposive sampling technique from two general hospitals in Central Sulawesi. The questionnaires were the International Physical Activity Questionnaire (IPAQ) and the World Health Organization Quality of Life-BREF (WHOQOL-BREF). Descriptive statistics (frequency, presentation, mean, standard deviation, range) and bivariate analysis (Mann-Whitney, Kruskal-Wallis, Spearman Rank) were used to investigate the relationships between variables. Results: Physical activity had a significant correlation with QoL domains of physical, psychological, and social (r = 0,26 - 0,34; p < 0,01). Conclusions: Hypertensive patients who have optimal physical activity also have a good perception of their physical, psychological, and social status.
Antioxidant and Antimicrobial Agents from Avocado (Persea americana) Seed Extract Encapsulated in Gum Arabic through Spray Drying Method
Authors: Kautsar Duhaul Biqal , Rois Mahardika F. , Faizah Nurul , Widiyastuti Widiyastuti , Nurtono Tantular , Setyawan Heru 
Published: January 2023

In this work, the objective is to utilize avocado seed extract as a cheap alternative source of active compounds and was successfully encapsulated using gum arabic by spray drying as an antioxidant and antimicrobial agent. First, the active compounds were extracted from avocado seed using solvent n-hexane and followed by solvent separation using rotary vacuum evaporator. Next, gum arabic as the encapsulation agent was added to avocado seed extract to form an emulsion, then spray-dried with drying air at a temperature of 140 °C. The mass ratio of avocado seed was varied at extract: gum arabic of 5:5, 5:10, 5:15, and 5:20. Then, the particle morphology, yield, moisture content, encapsulation efficiency, loading capacity, chemical groups, antioxidant activity, and antibacterial ability were analyzed to investigate the performance of the encapsulation particles. Among the ranges studied, the extract–gum arabic with a mass ratio of 5:10 exhibited the best properties of yield powder, loading capacity, and encapsulation efficiency at 49.78%, 3.43%, and 7.33%, respectively. The encapsulated particles have smooth surface, crackless, lower indentation, and a single-core encapsulation structure with an average diameter of 4.60 μm. Besides, the stability of antioxidant activity decreased by 2.36%, from 94.82% to 92.46% for four weeks of storage. They also performed antimicrobial activity against E. coli and S. aureus, which were maintained after seven days. Meanwhile for avocado seed extract only, the unencapsulated stability of antioxidant activity has continually decrease from 91.58% to 84.05% and performed no antimicrobial activity against E. coli after seven days.
Transformation of Condolence in the Digital Age: A Case Study on Turkish Culture
Authors: Serttaş Aybike , Sarıkaya Tugay 
Published: January 2023

<p>The purpose of this article is to demonstrate the practice of condolence of digital immigrants in Turkey. Although digital media technologies expand communication opportunities and networks, they also cause changes in social relations between people. Versatile communication has become possible thanks to digital media technologies as opposed to non-interactive or unilateral communication of conventional media. Nowadays, it is possible to send a message to dozens of people with just one click. As such, new attitudes and behaviors are observed in the society along with the developing possibilities of digital media. The hypothesis of the study is "digital immigrants that use social media platforms in Turkey has experienced a change in the practice of condolences." In this regard, the emphasis put on the changes in condolence practices that occur across Turkey is discussed along with new Internet technologies. We conducted interviews with 15 participants among the ages of 52 and 69 between April and June 2020. According to the findings, we see that many of the participants adopt traditional condolence practices, but they do not devalue the condolence practices that occur on social media. We observed that digital condolence practices have started to coexist with traditional condolence practices, but this change should not be perceived as the traditional one is beginning to be erased or disappeared. </p>
Los eventos corporativos y la digitalización de los sentidos en el metaverso: estudio de caso de la marca de moda Gucci
Authors: Salanqueda i Mayor Mireia , Puntí Brun Mónica 
Published: January 2023

<p class="normal"><span lang="ca">Los metaversos se postulan como uno de los escenarios más próximos y como realidades inmersivas que podrán abrir nuevas posibilidades a medida que se avance en su desarrollo. El presente estudio pretende analizar si se pueden, y de qué forma, crear en el metaverso eventos corporativos utilizando tecnologías de digitalización de los sentidos y técnicas del marketing experiencial y sensorial. En consecuencia, en esta investigación se ha comprobado que el metaverso permite la fusión de las emociones y los sentidos con la tecnología, lo que supone una oportunidad para ofrecer experiencias distintas a las del mundo físico en un contexto en el que es esencial cautivar al público joven y en el que los eventos y las comunicaciones de las empresas deben ir un paso más allá. A través de una entrevista, un análisis de contenido y el estudio de caso de la marca Gucci, se ha corroborado que la inserción en el metaverso por parte de las marcas ya es posible. A su vez, se ha confirmado la importancia de integrar el metaverso como parte de la estrategia y como el espacio idóneo para abastecer todos los ámbitos digitales. El metaverso puede ofrecer experiencias únicas a los consumidores que buscan disfrutar de los productos y servicios de manera interactiva e inmersiva a través de los cinco sentidos. </span></p>
Book Review THE METAVERSE and How It Will Revolutionize Everything, by Mathew Ball,
Authors: Gürkan Hasan 
Published: January 2023

<p>Book Review<br />THE METAVERSE and How It Will Revolutionize Everything, by Mathew Ball,<br />Liveright Publishing Corporation, 2022, 352 pages, ISBN: 978-1324092032</p><p>Dr. Hasan Gürkan<br />https://orcid.org/0000-0002-3805-9951</p>
Del “Being Digital” a “El metaverso. Un viaje hacia la Tierra digital”.
Authors: Puig Borràs Núria 
Published: January 2023

<p>RESEÑA DEL LIBRO “EL METAVERSO. UN VIAJE HACIA LA TIERRA DIGITAL.”</p><p>De SANGKYUN KIM</p><p>Editorial: ANAYA. </p><p>PÀGS 186</p>
The Metacognitive Strategy to Achieve Listening Comprehension in Kulni Modern Islamic Boarding School
Authors: Munawar Tanjung Muhamad Farhan , Heryatun Yayu , Sa'diah Siti 
Published: January 2023

Metacognitive is the process of thinking about our minds, which is how a process, and control that information to find new understanding/knowledge and seek relationships with other knowledge. The purpose of this study is to discover how students in class XI of Kulni Modern Islamic Boarding School at Cikande, Serang Banten in use English listening metacognitive strategies, as well as the differences in improving English listening comprehension among students before and after receiving metacognitive learning. The population of this study included 61 students from class XI of Kulni Modern Islamic Boarding School at Cikande, Serang Banten. The sample consisted of 29 students from A class XI. The researcher used quantitative data analysis in this study. Data is gathered by administering tests to the class. There are two kinds of tests: pre-test and post-test. According to the study's findings, the average pre-test score at researcher Modern Islamic Boarding School at Cikande, Serang Banten was 40.41, and the average post-test score in the experimental class was 57.21. Based on the data presented above, it is possible to conclude that there is a 41.5 percent change in learning outcomes. Based on the result of the study, applying metacognitive strategies for learning can help students become interested in listening activities and can be an alternative innovation in learning listening.
Evaluation of Zerumbone as an EGFR Tyrosine Kinase Inhibitor by Molecular Docking Method
Authors: YONAR Dilek , BABA Burcu , KARAYEL Arzu 
Published: January 2023

Objective: EGFR-TK domain is of great importance in the initiation and progression of various cancer types, especially lung cancer. The existing EGFR-TK inhibitors have numerous side effects, which make them improper to be utilized as cancer therapeutics. In this study, we aimed to analyze the activity of zerumbone as an anticancer agent targeting EGFR by molecular docking approach and to evaluate its activity in comparison with curcumin.
Material and Method: MEP and HOMO-LUMO analyses were achieved at B3LYP/6-31G(D,P) level to evaluate electrostatic interactions that affect binding of EGFR with zerumbone and curcumin. Their binding energies were determined by molecular docking and compared with erlotinib as reference ligand.
Result and Discussion: Docking studies showed higher bindings (lower binding energy) for curcumin and zerumbone with binding energies -8.0 and -7.6 kcal/mol, respectively, compared to erlotinib (-7.54 kcal/mol). However, there is no significant difference between them. The ΔE energy gap of zerumbone and curcumin were 5.09 and 3.68 eV which implies that these compounds have more stability but less electronegativity in comparison with erlotinib (ΔE=2.22eV). Also, zerumbone showed strong hydrogen bond interactions with EGFR, making it candidate as EGFR inhibitor, as did both in curcumin and erlotinib. It was concluded that zerumbone may have potential for inhibitory activity against EGFR-TK.
Psychological and sociological characteristics of students suffering from nightmares
Authors: Kostin R. K. , Rozhnov I. A. , Korabel'nikova E. A. , Yakushina I. I. 
Published: January 2023

Aim. To assess the impact of nightmarish dreams on various aspects of medical students' lives.Materials and methods. A sociological survey was conducted among students of 1–6 courses of five medical universities using an online form which included the following questionnaires: the Pittsburgh Sleep Quality Index, the Hamburg Nightmare Questionnaire, the Insomnia Severity Scale, the Hospital Anxiety and Depression Scale, the Beck Anxiety and Depression Scale. Academic performance was assessed according to the average score of the student's record book according to a 5-point system.Results and conclusions. A high prevalence of both insomnia and nightmares among medical students was found. The high frequency of nightmares was associated with high levels of anxiety and depression. The frequency of nightmares was associated with deterioration of sleep quality, frequency and degree of sleep impairment. Nightmarish dreams had a negative impact on the quality of cognitive activity assessed by academic performance.
Laser speckle contrast imaging to monitor microcirculation: An effective method to predict outcome in patients with sepsis and septic shock
Authors: Ruan Zhengshang , Li Ran , Dong Wenwen , Cui Zhilei , Yang Hui , Ren Rongrong 
Published: January 2023

Background: This study examines the microcirculation of patients with sepsis and septic shock using Laser Speckle Contrast Imaging (LSCI) technology, to enhance monitoring and predict outcomes of sepsis and septic shock.Methods: From 01 July 2021, to 31 January 2022, 44 patients diagnosed with septic shock and sepsis were included in the study, their clinical data were collected, and LSCI was used to monitor the mean peripheral blood flow perfusion index (PI).Results: The average peripheral blood flow PI of septic shock patients was significantly lower than that of septic patients, with a cutoff value of 26.25. The average peripheral blood flow PI negatively correlated with acute physiology and chronic health evaluation (APACHE) Ⅱ score (p = .01 &lt; .05), sequential organ failure assessment (SOFA) score (p &lt; .01), and lactic acid levels (p = .01 &lt; .05). We report average peripheral blood flow no correlation with age, mean arterial pressure, body temperature, oxygen saturation, heart rate, and body mass index. There was no correlation with procalcitonin, C-reactive protein (CRP), red blood cell distribution width, or platelet distribution width (p &gt; .05). PI significantly correlated with the group sepsis and septic shock (p &lt; .001, r = −.865). And PI significantly correlated with the outcome or mortality (p = .007 &lt; .05, r = −.398). The ROC curve was calculated for PI and the sensitivity was 81.3%, and the specificity was 75% when PI cutoff value chooses 20.88.Conclusion: LSCI technology successfully detected the fingertip microcirculation of patients with septic shock. LSCI can reliably differentiate patients with sepsis vs patients with septic shock. Additionally, the average peripheral blood PI negatively correlated with APACHE Ⅱ, SOFA score, and lactate acid levels, providing useful and supplementary information for the diagnosis and monitoring of septic shock. Trial registration: Chictr2100046761. Registered on May 28, 2021.Clinical Trial Registration:clinicaltrials.gov, identifier Chictr2100046761
Impaired Diastolic Function Predicts Improved Ischemic Myocardial Flow by Mechanical Left Ventricular Unloading in a Swine Model of Ischemic Heart Failure
Authors: Sakata Tomoki , Watanabe Shin , Mazurek Renata , Mavropoulos Spyros , Romeo Francisco , Yamada Kelly P. , Ishikawa Kiyotake 
Published: January 2023

Background: Impact of mechanical left ventricular (LV) unloading on myocardial tissue perfusion and its regulating factors remain unclear. This study was conducted to elucidate the predictors of regional blood flow (RBF) improvement by mechanical LV unloading.Materials and Methods: One to four weeks after percutaneous induction of myocardial infarction (MI), Yorkshire pigs (n = 15) underwent mechanical LV unloading using Impella CP. Hemodynamic parameters were collected prior to LV unloading. RBF in infarct, border and remote myocardium were measured by fluorescent microsphere injections before and 120 min after LV unloading.Results: RBF showed variable responses to mechanical LV unloading. While infarct RBF improved in general (0.33 ± 0.13 to 0.42 ± 0.19 mL/min/g, p = 0.06), there were a few pigs that showed little improvement. Meanwhile, there were no clear trends in the border (1.07 ± 0.47 to 1.02 ± 0.65 mL/min/g, p = 0.73) and remote myocardial RBF (1.25 ± 0.52 to 1.23 ± 0.68 mL/min/g, p = 0.85). In the simple linear regression analysis, cardiac output, mean pulmonary arterial wedge pressure, mean left atrial pressure, minimum LV pressure, end-diastolic LV pressure, maximum dP/dt, slope of end-diastolic pressure-volume relationship (EDPVR) and end-diastolic wall stress were significantly associated with % change of infarct RBF. In the multiple regression model, slope of EDPVR and maximum dP/dt remained as independent predictors of infarct RBF change.Conclusion: Steeper EDPVR and lower maximum dP/dt were associated with increased blood perfusion in the infarct area after LV unloading. Our data suggests mechanical LV unloading is more beneficial in post-MI patients with high diastolic pressure associated with increased LV stiffness and in those with worse cardiac contractility.