bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predicting variable-length paths in networked systems using multi-order generative models
Authors: Gote Christoph , Casiraghi Giona , Schweitzer Frank , Scholtes Ingo 
Published: September 2023

AbstractApart from nodes and links, for many networked systems, we have access to data on paths, i.e., collections of temporally ordered variable-length node sequences that are constrained by the system’s topology. Understanding the patterns in such data is key to advancing our understanding of the structure and dynamics of complex systems. Moreover, the ability to accurately model and predict paths is important for engineered systems, e.g., to optimise supply chains or provide smart mobility services. Here, we introduce MOGen, a generative modelling framework that enables both next-element and out-of-sample prediction in paths with high accuracy and consistency. It features a model selection approach that automatically determines the optimal model directly from data, effectively making MOGen parameter-free. Using empirical data, we show that our method outperforms state-of-the-art sequence modelling techniques. We further introduce a mathematical formalism that links higher-order models of paths to transition matrices of random walks in multi-layer networks.
Digital twins of organization: implications for organization design
Authors: Lyytinen Kalle , Weber Barbara , Becker Markus C. , Pentland Brian T. 
Published: September 2023

AbstractThe recent rise of using digital representations for products and processes has created a movement to use ‘digital twins’ for organization design. We provide an overview of the notion of digital twin as a synchronized, real-time two-way interacting digital representation of the real-world phenomenon it is expected to replicate as a twin. The claim of a two-way causal connection between the real-world and the digital representation makes the current rhetoric about Digital Twins especially problematic. To grasp the challenges involved in Digital Twins of Organizations (DTO), we start from Digital Twins of Things (DTT) and Digital Twins of Business Processes (DTBP). We analyze and compare different kinds of digital twins using Peircean theory of semiotic relationships, which differentiate between signals, icons, and symbols. We posit that in order to fully model organizations as digital twins, an organization designer needs to model features of organizations that are not present in DTTs and DTBPs, such as agency, conflict, and emergence. Given the inevitable presence of symbolic phenomena, we speculate to what extent it is possible to move towards full DTOs, what characteristics broader DTOs need to have, and what benefits more extensive use of DTOs will offer for organization designers. We finally offer pointers towards a research agenda for DTOs that have the potential to improve organization designs and contribute to theory on organization design.
Situational analysis of antimicrobial stewardship program (ASP) among public and private sector tertiary care hospitals in Karachi, Pakistan: A qualitative case study
Authors: Pethani Asma , Riaz Atif , Perveen Shagufta , Saleem Ali Faisal 
Published: September 2023

AbstractObjective:To assess the current status of implementation of the Antimicrobial Stewardship Program (ASP) across Tertiary Care Hospitals in Karachi, Pakistan.Design:Exploratory qualitative case study.Setting:Public and private tertiary care hospitals in Karachi, PakistanParticipants and Methods:The study data were collected from 3 public and 4 private tertiary care hospitals. Twenty-eight in-depth interviews were conducted from the Chief Executive Officer, Chief Medical Officer, Medical Superintendent, and departmental heads of internal medicine, general surgery, and pediatric, respectively. Purposive sampling was done to include higher and middle managers, whereas the infectious diseases consultant, infectious diseases/clinical pharmacist, and clinical microbiologist were interviewed through snowball sampling methodology. Analysis was done using NVivo. Data were source-triangulated within and among the study setting and study participants.Results:We found that more than two-thirds (n = 5, 71%) of tertiary care hospitals in Karachi do not have a structured ASP which includes major public sector hospitals (n = 3, 43%) and half of the private sector hospitals (n = 4, 29%). The study results led to four broad themes, (1) ASP structure, (2) ASP interventions, (3) hospital medical record-keeping system, and (4) structured way for analyzing and reporting mechanism of data related to the ASP. At H1 and H2, there was a consistency in ASP structure and interventions, whereas paucity seen among remaining tertiary care hospitals.Conclusion:There is an alarming need for ASP in the public and private sector hospitals in Karachi. This study can inform future stakeholders regarding ASP and strategies for structural change at hospitals.
Early Eocene fossils elucidate the evolutionary history of the Charadriiformes (shorebirds and allies)
Authors: Mayr Gerald , Kitchener Andrew C. 
Published: September 2023

AbstractWe report charadriiform and charadriiform-like birds from the early Eocene London Clay of Walton-on-the-Naze (Essex, UK). A partial skeleton of a small modern-type charadriiform is described as a new species, Charadriisimilis essexensis n. gen. n. sp., and most closely resembles taxa of the Charadrii (plovers, stilts, oystercatchers, and other “wader-like” shorebirds). Affinities to this clade were also supported by phylogenetic analyses, which placed the fossil as the sister taxon of either the Burhinidae or all crown group Charadrii. In addition, we identify specimens of the charadriiform-like taxon Scandiavis, which was before known only from the early Eocene Fur Formation in Denmark. Associated limb elements of two individuals are classified as Scandiavis cf. mikkelseni Bertelli et al., 2013, and remains of two further individuals are tentatively assigned to Scandiavis. The presence of a processus supracondylaris dorsalis on the previously unknown humerus corroborates charadriiform affinities of Scandiavis, whereas a plesiomorphic hypotarsus morphology indicates a position outside crown group Charadriiformes. Charadriisimilis essexensis is one of the earliest modern-type charadriiforms, and the holotype of the species is the most substantial early Paleogene fossil record of a charadriiform bird. Together with Scandiavis, as the best-represented taxon to be considered as a stem group charadriiform, it provides the basis for an improved understanding of the evolutionary history of charadriiform birds.UUID: http://zoobank.org/ca15ee81-09e8-4577-8beb-a362debf6636
Effects of diets containing fish oils or fish oil concentrates with high cetoleic acid content on the circulating cholesterol concentration in rodents. A systematic review and meta-analysis
Authors: Mjaatveit Margrete , Oldernes Helle , Gudbrandsen Oddrun Anita 
Published: September 2023

AbstractHypercholesterolaemia is a major risk factor for CVD. Fish intake is associated with lower risk of CVD, whereas supplementation with n-3 long-chain PUFA (LC-PUFA) has little effect on the cholesterol concentration. We therefore investigated if cetoleic acid (CA), a long-chain MUFA (LC-MUFA) found especially in pelagic fish species, could lower the circulating total cholesterol (TC) concentration in rodents. A systematic literature search was performed using the databases PubMed, Web of Science and Embase, structured around the population (rodents), intervention (CA-rich fish oils or concentrates), comparator (diets not containing CA) and the primary outcome (circulating TC). Articles were assessed for risk of bias using the SYRCLE’s tool. A meta-analysis was conducted in Review Manager v. 5.4.1 (the Cochrane Collaboration) to determine the effectiveness of consuming diets containing CA-rich fish oils or concentrates on the circulating TC concentration. Twelve articles were included in the systematic review and meta-analysis, with data from 288 rodents. Consumption of CA-rich fish oils and concentrates resulted in a significantly lower circulating TC concentration relative to comparator groups (mean difference −0·65 mmol/l, 95 % CI (−0·93, −0·37), P < 0·00001), with high statistical heterogeneity (I2 = 87 %). The risk of bias is unclear since few of the entries in the SYRCLE’s tool were addressed. To conclude, intake of CA-rich fish oils and concentrates prevents high cholesterol concentration in rodents and should be further investigated as functional dietary ingredients or supplements to reduce the risk for developing CVD in humans.
The genus Schaereria Körb. in Australia
Authors: Kantvilas Gintaras 
Published: September 2023

AbstractFive species of Schaereria Körb. are known to occur in Australia (including Tasmania). The new species S. australis Kantvilas is described from alpine Tasmania and New South Wales; it is characterized by a thallus lacking lichen substances, apothecia with only brown pigments, and ellipsoid, uniseriate ascospores, 10−17 × 6−9 μm. Also treated are: S. bullata Kantvilas, endemic to Tasmania; S. dolodes (Nyl. ex Hasse) Schmull & T. Sprib., first described from North America and recorded here for the first time from the Southern Hemisphere (Tasmania); the bipolar S. fuscocinerea (Nyl.) Clauzade & Cl. Roux and the Australian endemic S. xerophila Rambold & H. Mayrhofer, both recorded for the first time from Tasmania. The species are illustrated and an identification key is provided.
Towards a nomenclatural clarification of the Peltigera ponojensis/monticola clade including metagenomic sequencing of type material and the introduction of P. globulata Miadl. & Magain sp. nov.
Authors: Miadlikowska Jolanta , Magain Nicolas , Medeiros Ian D. , Pardo-De la Hoz Carlos J. , Carbone Ignazio , LaGreca Scott , Barlow Thomas , Myllys Leena , Schmull Michaela , Lutzoni François 
Published: September 2023

AbstractPeltigera globulata Miadl. & Magain, a new species in the P. ponojensis/monticola species complex of section Peltigera, is formally described. This clade was previously given the interim designation Peltigera sp. 17. It is found in sun-exposed and xeric habitats at high altitudes in Peru and Ecuador. Peltigera globulata can be easily recognized by its irregularly globulated margins covered mostly by thick, white pruina, somewhat resembling the sorediate thallus margins of P. soredians, another South American species from section Peltigera. The hypervariable region of ITS1 (ITS1-HR), which is in general highly variable among species of section Peltigera, does not have diagnostic value for species identification within the P. ponojensis/monticola complex. Nevertheless, no significant level of gene flow was detected among eight lineages representing a clade of putative species (including P. globulata) within this complex. ITS sequences from the holotype specimens of P. monticola Vitik. (collected in 1979) and P. soredians Vitik. (collected in 1981) and lectotype specimens of P. antarctica C. W. Dodge (collected in 1941) and P. aubertii C. W. Dodge (collected in 1952) were successfully obtained through Sanger and Illumina metagenomic sequencing. BLAST results of these sequences revealed that the type specimen of P. monticola falls within the P. monticola/ponojensis 7 clade, which represents P. monticola s. str., and confirmed that the type specimen of P. aubertii falls within a clade identified previously as P. aubertii based on morphology. The ITS sequence from the type specimen of P. soredians, which superficially resembles P. globulata, confirms its placement in the P. rufescens clade. Finally, we discovered that the name P. antarctica was erroneously applied to a lineage in the P. ponojensis/monticola clade. The ITS sequence from the type specimen of P. antarctica represents a lineage within the P. rufescens clade, which is sister to the P. ponojensis/monticola clade.
Can we trust iNaturalist in lichenology? Evaluating the effectiveness and reliability of artificial intelligence in lichen identification
Authors: Munzi Silvana , Isocrono Deborah , Ravera Sonia 
Published: September 2023

AbstractiNaturalist is a widely-utilized platform for data collection and sharing among non-professional volunteers and is widely employed in citizen science. This platform's data are also used in scientific studies for a wide range of purposes, including tracking changes in species distribution, monitoring the spread of alien-invasive species, and assessing the impacts of urbanization and land-use change on biodiversity. Lichens, due to their year-round presence on trees, soil and rocks, and their diverse shapes and colours, have captured the attention of iNaturalist users, and lichen records are widely represented on the platform. However, due to the complexity of lichen identification, the use of data collected by untrained, or poorly trained volunteers in scientific investigation poses concerns among lichenologists. To address these concerns, this study assessed the reliability of lichen identification by iNaturalist users by comparing records on the platform with identifications carried out by experts (experienced lichenologists) in three cities where citizen science projects were developed. Results of this study caution against the use of unchecked data obtained from the platform in lichenology, demonstrating substantial inconsistency between results gathered by iNaturalist users and experts.
Synthesizing Methuselah: The Question of Artificial Agelessness
Authors: Gibson Richard B. 
Published: September 2023

AbstractAs biological organisms, we age and, eventually, die. However, age’s deteriorating effects may not be universal. Some theoretical entities, due to their synthetic composition, could exist independently from aging—artificial general intelligence (AGI). With adequate resource access, an AGI could theoretically be ageless and would be, in some sense, immortal. Yet, this need not be inevitable. Designers could imbue AGIs with artificial mortality via an internal shut-off point. The question, though, is, should they? Should researchers curtail an AGI’s potentially endless lifespan by deliberately making it mortal? It is this question that this article explores. First, it considers what type of AGI is under discussion before outlining how such beings could be ageless. Then, after clarifying the type of immortality under discussion and arguing that imbuing an AGI with synthetic aging would be person-affecting, the article explores four core conundrums: (i) deliberately causing a morally significant being’s death; (ii) immortality’s associated harms; (iii) concerns about immortality’s unequal assignment; and (iv) the danger of immortal AGI overlords. The article concludes that while prudence requires we create an aging AGI, in the face of the material harm such an action would constitute, this is an insufficient reason to justify doing so.
73% of the observed bilingual (dis)advantageous effects on cognition stem from sociolinguistic factors: A systematic review
Authors: Masullo Camilla , Dentella Vittoria , Leivada Evelina 
Published: September 2023

AbstractBeing bilingual confers certain behavioral effects. Determining their precise origin is of utmost importance given the need to avoid unjust misattribution of labels such as “bilingual (dis)advantage” to people's bilingual experiences. To this end, this systematic PRISMA-based review aims to shed light on the social and sociolinguistic origins of bilingualism-related behavioral effects. Analyzing 368 studies, we find that 73.41% of the 267 studies that report such effects attribute them either to sociolinguistic factors alone or to the interaction of sociolinguistic and cognitive factors. Linking the two fronts, type of effect and origin of effect, we find a previously unreported correlation: Studies that find evidence for bilingual disadvantages are more likely to claim a sociolinguistic origin, while studies that report advantages are more likely to link their findings to a cognitive origin. We discuss these results and present the key components of a sociolinguistic theory of the origin of bilingual effects.
New Geochronological Age Constraint and Chemostratigraphy for Aptian Lacustrine Strata, Cedar Mountain Formation, Utah
Authors: Suarez Marina B. , Al Suwaidi Aisha , Montgomery Elizabeth H. , Kirkland James I. , Andrew Joe , Mclean Noah , Möller Andreas , Ludvigson Gregory , Suarez Celina A. 
Published: September 2023

AbstractThe Early Cretaceous is an important time of transition in Earth history, marked by a succession of oceanic anoxic events and carbon cycle perturbations that drove changes on land and in the ocean. The need for more precise geochronologic constraints in terrestrial sediments of Early Cretaceous age that record faunal and floral transitions is especially critical. The Cedar Mountain Formation (CMF) is a continental lithostratigraphic unit that hosts a trove of paleoclimate archives and important dinosaurian fossil localities. Determining the timing of deposition of CMF strata has been an ongoing effort for many years. Here, we present new lithostratigraphic and carbon isotope chemostratigraphic data along with high‐precision radiometric ages to further constrain the Ruby Ranch Member of the CMF at a unique locality referred to as “Lake Carpenter,” where a thick section of dominantly lacustrine strata overlies fluvial‐overbank to palustrine strata more typical of other Ruby Ranch Member outcrops. A bentonite bed near the base of the section provides one of the most precise ages yet determined within the Ruby Ranch Member of 115.92 ± 0.14 Ma via CA‐ID‐TIMS U‐Pb analysis of zircons. The age and the trends in the carbon isotope record indicate that the Lake Carpenter sediments were deposited entirely within the late Aptian Stage. These unique new data provide an important step toward improving our understanding of the timing of Early Cretaceous evolutionary and paleoclimate events.
Predicting Tropical Cyclone‐Induced Sea Surface Temperature Responses Using Machine Learning
Authors: Cui Hongxing , Tang Danling , Mei Wei , Liu Hongbin , Sui Yi , Gu Xiaowei 
Published: September 2023

AbstractThis study proposes to construct a model using random forest method, an efficient machine learning‐based method, to predict the spatial structure and temporal evolution of the sea surface temperature (SST) cooling induced by northwest Pacific tropical cyclones (TCs), a process of the so‐called wind pump. The predictors in use include 12 predictors related to TC characteristics and pre‐storm ocean conditions. The model is shown to skillfully predict the spatiotemporal evolutions of the cold wake generated by TCs of different intensity groups, and capture the cross‐case variance in the observed SST response. Another model is further built based on the same method to assess the relative importance of the 12 predictors in determining the magnitude of the maximum cooling. Computations of feature scores of those predictors show that TC intensity, translation speed and size, and pre‐storm mixed layer depth and SST dominate, depending on the area where the cooling is considered.
Interior Route and Seasonal Dynamics of the Meridional Current in the Eastern Indian Ocean Tropical Gyre
Authors: Zhao Zhangzhe , Wu Wei , Xia Yifan , Du Yan 
Published: September 2023

AbstractThe eastern boundary current of the tropical Indian Ocean (IO) connects the equatorial/south tropical IO, contributing to the meridional heat and salinity exchange. As a part of the IO tropical gyre, the meridional current in the eastern IO tropical gyre (East Sumatra Current, ESC) flows southward in the mean state. However, the route of this current varies with months. Drifter trajectories display an exceptional route that turns southeastward before reaching Sumatra in the austral winter and spring, considered the interior ESC. This study uses observations and reanalysis data sets to investigate the seasonal structure and forcing mechanisms behind the interior ESC. The velocity is decomposed into geostrophic and wind‐driven components. The results suggest that the geostrophic component plays a dominant role in the ESC recirculating early from April to June. The southward geostrophic currents are mainly caused by positive zonal temperature gradients, which are induced by both the cold anomaly of the Chagos Dome and the warm water carried by the Indonesian Throughflow, particularly in April and May. Meanwhile, the annual Rossby wave contributes to the temperature anomaly of the Chagos Dome. During the monsoon that prevails after July, the wind‐driven component increases and becomes the primary forcing, accompanying the slowdown of geostrophic velocity. Therefore, the local wind stress, wave propagation, and water mass transport account for the formation of the seasonal interior ESC.
Humic acid-dependent respiratory growth of Methanosarcina acetivorans involves pyrroloquinoline quinone
Authors: Song Yuanxu , Huang Rui , Li Ling , Du Kaifeng , Zhu Fanping , Song Chao , Yuan Xianzheng , Wang Mingyu , Wang Shuguang , Ferry James G , Zhou Shungui , Yan Zhen 
Published: September 2023

Abstract
Although microbial humus respiration plays a critical role in organic matter decomposition and biogeochemical cycling of elements in diverse anoxic environments, the role of methane-producing species (methanogens) is not well defined. Here we report that a major fraction of humus, humic acid reduction enhanced the growth of Methanosarcina acetivorans above that attributed to methanogenesis when utilizing the energy sources methanol or acetate, results which showed both respiratory and fermentative modes of energy conservation. Growth characteristics with methanol were the same for an identically cultured mutant deleted for the gene encoding a multi-heme cytochrome c (MmcA), results indicating MmcA is not essential for respiratory electron transport to humic acid. Transcriptomic analyses revealed that growth with humic acid promoted the upregulation of genes annotated as cell surface pyrroloquinoline quinone (PQQ)-binding proteins. Furthermore, PQQ isolated from the membrane fraction was more abundant in humic acid-respiring cells, and the addition of PQQ improved efficiency of the extracellular electron transport. Given that the PQQ-binding proteins are widely distributed in methanogens, the findings extend current understanding of microbial humus respiration in the context of global methane dynamics.
Evaluation of a custom-made mandibular repositioning device for the treatment of obstructive sleep apnoea syndrome
Authors: Flouris Lampros , Millar Brian 
Published: September 2023

AbstractObstructive sleep apnoea (OSA) is a common, chronic condition that affects breathing during sleep. The gold standard for treatment is continuous positive airway pressure (CPAP) which is often not well-tolerated. Mandibular repositioning appliances (MRDs) are an alternative that dentists may be requested to provide.The purpose of this audit is to evaluate the effectiveness of an MRD in improving the Oxygen Desaturation Index (ODI) and Epworth Sleepiness Scale (ESS). A total of 52 patients diagnosed with OSA in an NHS hospital respiratory clinic were fitted with an MRD. Analysis of the digitally recorded oximeter signals was recorded among other treatment outcomes before and 6-8 weeks after the fit of the appliance.The meta-analysis of the audit data showed supportive evidence for MRD treatment in OSA patients. There was a statistically significant reduction in ODI and ESS. The audit population consisted of 138 patients (91 men, 47 women; mean age: 49.49 ± 11.93 years). The ODI outcomes improved significantly, from 10.68 to 6.58 (p <0.02). The ESS improved significantly from 9.46 to 6.02 (p <0.01).This audit demonstrates that MRDs are effective and should be considered as an alternative to CPAP in some specific OSA phenotypes.