bluuebunny/crossref_metadata_2025_split huggingface dataset:
Benefit of a laparoscopic jejunostomy feeding catheter insertion to prevent bowel obstruction associated with feeding jejunostomy after esophagectomy
Authors: Kitagawa Hiroyuki , Yokota Keiichiro , Utsunomiya Masato , Tanaka Tomoki , Namikawa Tsutomu , Kobayashi Michiya , Seo Satoru 
Published: September 2023

Abstract
The proximity of the jejunostomy site to the midline might be associated with bowel obstruction, and we have introduced laparoscopic jejunostomy (Lap-J) to reduce jejunostomy’s left lateral gap. We evaluated 165 patients who underwent esophagectomy for esophageal cancer between February 2013 and November 2022 to clarify the benefits of Lap-J compared to other methods. The patients were classified into three groups according to the method of feeding catheter insertion: jejunostomy via small laparotomy (J group), gastroduodenostomy (GD group), and laparoscopic jejunostomy (Lap-J group). The J, GD, and Lap-J groups included 79, 69, and 17 patients, respectively. Surgery for bowel obstruction associated with the feeding jejunostomy catheter (BOFJ) was performed on 11 in the J group. Comparing the J and Lap-J groups, the distance between the jejunostomy and midline was significantly longer in the Lap-J group (50 mm vs. 102 mm; P < 0.001). Regarding surgery for BOFJ, the distance was significantly shorter in the surgery group than in the non-surgery group (43 mm vs. 52 mm; P = 0.040). During esophagectomy, Lap-J can prevent BOFJ by placing the jejunostomy site at the left lateral position to the midline and reducing the left lateral gap of the jejunostomy.
Adjuvanting Property of Aqueous Extract of the Indian Mistletoe, Dendrophthoe falcata
Authors: M Raja , Kanagaraj Vinoth , Subramani Parasuraman Aiya , Michael R Dinakaran , TR Prabha 
Published: September 2023

Abstract
The Indian mistletoe, Dendrophthoe falcata, has been traditionally used in Ayurvedic medicine for its various therapeutic properties. Adjuvants are substances that enhance the immune response to antigens, thereby improving the effectiveness of vaccines or immunotherapies. In this study, the aqueous extract of D. falcata was evaluated for its adjuvanting potential in Nile tilapia, Oreochromis niloticus. An aqueous extract (AE) was prepared from the dried leaves of D. falcata. The adjuvant activity was assessed by co-administering the extract with a heat inactivated Streptococcus agalactiae vaccine in O. niloticus. The immune response was evaluated by measuring the serum lysozyme activity and the serum antibody levels. Results showed that the AE significantly enhanced the specific and nonspecific immune responses to the model antigen. It increased the serum lysozyme activity and elicited a robust production of specific antibodies, suggesting a potentiated nonspecific and specific immune response. The adjuvanting property of the aqueous extract of D. falcata suggests its potential utility in enhancing the effectiveness of vaccines or immunotherapies.
Weakly nonlinear bio-convection in a porous media under temperature modulation and internal heating
Authors: Kiran Palle , Manjula SH. 
Published: September 2023

Abstract

This paper investigating the effects of thermal modulation and internal heating on Darcy-Brinkman bio-convection in a Newtonian porous medium containing gyrotactic microorganisms. A weak nonlinear stability analysis is used to analyze the stationary mode of bioconvection with low modulation and internal heating. The heat transport is measured by the mean Nusselt number, which is determined by the Ginzburg-Landau equation (GLE). The solvability condition is used at the third order of the perturbed parameter is used to calculate the GLE. The results are visually displayed to show how the system parameters affect heat transfer.The results demonstrate a progressive impact on the heat transfer of both Vadasz number and modulation amplitude. However, heat transfer is reduced as cell eccentricity and the modified bioconvection Rayleigh number increase. Internal heating causes the system to become unstable and transfer heat more quickly. Both bioconvection and internal Rayleigh numbers (Rb and R i) are of opposite effects on mean Nu. It is also found that only OPM/LBM are effective on controlling heat transfer than IPM. Additionally, it is found that only OPM/LBM are more successful at regulating heat transport than IPM. Further, it is found that the convective heat transfer process may be delayed, due to asymmetries and irregularities (α ̸ = 0) of microorganisms than spherical-shaped microorganisms (α = 0).
Global Burden and Epidemic Trends of Gout Attributable to High Body Mass Index from 1990 to 2019
Authors: Jin Zhaokai , Wang Zhengming , Wang Rui , Xiang Sicheng , Tang Yi , Zhang Weiqing , Tong Peijian , Gu Yong , Lv Shuaijie 
Published: September 2023

Abstract
Gout is an inflammatory and metabolic disease characterized by arthritis and elevation of the serum uric acid (SUA) level. More and more studies have shown that high body mass index (BMI) has become one of the most important risk factors for gout. We used the data of gout burden attributed to high body mass index (BMI) from global burden of disease (GBD) study 2019 to provide insights for reducing the global burden of gout. From 1990 to 2019, the prevalence and DALYs of gout caused by high BMI worldwide has been increasing. The burden of gout caused by high BMI is heavier in the elderly group and countries and regions with high SDI. Developing a weight management plan and lifestyle habits for groups severely affected by gout will effectively reduce the local disease and economic burden.
Automorphisms of large-type free-of-infinity Artin groups.
Authors: Vaskou Nicolas 
Published: September 2023

Abstract

We compute explicitly the automorphism and outer automorphism group of all large-type free-of-infinity Artin groups. Our strategy involves reconstructing the associated Deligne complexes in a purely algebraic manner, i.e. in a way that is independent from the choice of standard generators for the groups.
The concentrations of selective endocrine disruptors in milk from different lactation periods of cows
Authors: SIMSEK Ilker , KUZUKIRAN Ozgur , BOZTEPE Ummu Gulsum , TOPRAK Meryem , HARBI Mouhyadin Abdourahman , HARIRY Reza Ebrahimi , YURDAKOK-DIKMEN Begum , SIRELI Ufuk Tansel , Filazi Ayhan 
Published: September 2023

Abstract

Milk can be contaminated with organochlorine pesticides, polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers, and polycyclic aromatic hydrocarbons (PAHs), which are known as endocrine disruptors (EDCs). However, the relationship between the lactation period of cows and the residues of EDCs is unknown. Milk collected from cows during each lactation period was analyzed in terms of fat content and EDC residues. One or more contaminants were detected in almost all (98%) of the milk taken in three lactation periods. For example, 3 PCBs and 11 PAHs were found together in the first lactation period, and one more PAH was added to them in other periods. Also, it was seen that the most risky period was the first lactation period, followed by the third and second periods. The same ranking is valid for the fat content in milk. Thus, it was concluded that the excretion of lipophilic EDCs in milk is related to the fat content in milk, and the higher the fat content in milk, the more lipophilic EDCs are excreted in milk. However, regardless of the lactation period, when EDC residues are found in milk above the reference levels, it can be considered to disrupt the endocrine system in both adults and children.
Resilient intrusion detection system for adversarial attacks on Low-Rate DDoS
Authors: Droos Ayat , Al-Haija Qasem Abu 
Published: September 2023

Abstract
With the increase of attacks and illegal activities on networks, there has become an urgent need for systems that detect these activities and attacks and protect networks, such as intrusion detection systems that have an important role in protecting computer networks. Still, an adversarial attack has recently appeared against these systems, adversely affecting their performance. This paper proposes a framework that uses a Generative Adversarial Network (GAN) to generate adversarial instances to deceive IDS. The framework consists of two phases: building IDS models using two datasets and generating adversarial examples using GAN. Through careful evaluation, the GAN model achieves an impressive 99.9% success rate in generating samples that successfully evade intrusion detection systems, which sheds light on the potential vulnerabilities of IDSs for adversarial attacks.
Hesperidin Protects the Hippocampus histological architecture and Cognitive Functions of Albino Wistar Rats from Deleterious Effects of Diabetes Mellitus
Authors: Ahmed Ahmed S. , Mathew Liju S. , Mona Marwa M. , Docmac Omaima K. , Ibrahim Hoda A. , Elshamy Amira M. , Hantash Ehab M. , Elsisy Rasha A. 
Published: September 2023

Abstract
It was reported that hesperidin (HSD) is an ingredient extracted from lemon and orange that could play a role in the protection against neurodegenerative diseases. The link between the diabetic condition and cognitive ability is still not fully understood. The current research work was designed and conducted to help in understanding the link between HSD and cognitive functions in a rat model of diabetes. Forty rats were assigned into four groups, two of them developed diabetes. Rats received HSD which appeared to protect the cognitive functions and reduce the pro-inflammatory mediators. In conclusion, as presented in (Fig. 9), DM was found to affect the hippocampus by increasing IL-6, TNF-α, MDA, and ROS and decreasing IL-4, IL-10, SOD, and CAT. These could affect the histological architecture and are reflected as impairment of cognitive functions. On the other hand, HSD was found to play a protective role on the hippocampus against the deleterious effects of DM.
Levosimendan: current and possible areas of clinical application: A review
Authors: Boboshko Vladimir A. , Zibareva E. I. , Lomivorotov V. V. 
Published: September 2023

Levosimendan belongs to the class of calcium sensitizers, which exhibits its positive inotropic effects by increasing the affinity of troponin from the myocardium to calcium without additional myocardial oxygen demand, what favorably distinguishes it from catecholamines and their negative effects (myocardial ischemia, arrhythmias, vasoconstriction, hyperglycemia). In 2000, the drug was first used for the short-term treatment of decompensated chronic heart failure. After more than 20 years, the clinical use of levosimendan has covered a wide area among patients with pathology of the cardiovascular system and its use has gone far beyond the primary indications. To date, the drug has been studied in more than 200 randomized trials in patients with various clinical profiles: acute decompensation of chronic heart failure, progressive heart failure, acute myocardial infarction, cardiogenic shock, therapy of low cardiac output syndrome in cardiac surgery, perioperative use in pediatric cardiac surgery, septic shock, pulmonary hypertension, right ventricular failure, Takotsubo cardiomyopathy, patients with mechanical circulatory support devices. This review highlights the pharmacological features of the drug and key randomized clinical trials on the use of levosimendan in various categories of patients, in addition to officially recommended indications. The article also provides a brief overview of current and planned randomized trials.
Clinical and laboratory signs of multiple organ dysfunction in newborns with intraamniotic infection: prospective observational study
Authors: Aleksandrovich Yu. S. , Ivanov D. O. , Pavlovskaia E. Yu. , Pshenisnov Konstantin V. , Zemlyanoy D. A. 
Published: September 2023

INTRODUCTION: Assessment of the severity of the condition of newborns with intra-amniotic infection is extremely important for neonatal intensive care. OBJECTIVE: To study signs of multi-organ dysfunction in newborns with intra-amniotic infection. MATERIALS AND METHODS: 165 newborns who are being treated in the NICU were examined. The weight of the children was 1870 (1480–2550) g, the Apgar score at the first minute was 7 (6–7), at the fifth — 8 (7–8) points. Depending on the gestation period, the children were divided into 4 groups: I — 26–29, II — 30–33, III — 34–37 and IV — 38–40 weeks. In groups I–III, children with respiratory distress syndrome and intraamniotic infection prevailed, and in groups IV — with asphyxia. RESULTS: The maximum score on the NEOMOD scale of the ball is typical for children of groups I and IV: 4 (3–5) and 3 (1–4) points, respectively. The number of leukocytes in group IV newborns on the first day of treatment was statistically significantly higher than in groups II and III: 19.6 (8.5–43.7) vs 12.4 (5.8–33.1) and 12.5 (6.4–32.5), respectively (p = 0.003). Вase excess indicators in group I were statistically significantly lower than in group IV: −7.2 vs −4.2 (p < 0.001). The minimum concentration of C-reactive protein was typical for group I children — 1.7 (1.3–2.2) mg/l, which was significant compared to the indicators of other groups (p < 0.001). CONCLUSIONS: The most pronounced multiple organ dysfunction was observed in newborns with a gestation period of 26–29 and 38–40 weeks, which is confirmed by high scores on the NEOMOD scale, an increase in the number of leukocytes and neutrophil index indicators. Hemodynamic disorders in newborns with a gestation period of 26–29 weeks are the main factor determining the severity of the child's condition and the NEOMOD score.
Separation of pressure signals caused by waves traveling in opposite directions
Authors: Ferrante Marco , Zecchin Aaron 
Published: September 2023

Abstract
Hydraulic transient analysis allows the condition assessment of pipeline systems by the measurement of a system's transient pressure response subject to input pressure excitations. The detection of a pressure wave's arrival time and amplitude at one or more sections can be used to detect unexpected anomalies, such as leaks, blockages, or corroded sections. Wave separation approaches, based on signal processing techniques involving two sensors, enable a directional attribution to any measured pressure perturbations. Being able to determine the direction of origin of a perturbation through a signal-splitting approach greatly facilitates anomaly detection through the resolution of this ambiguity. The signal-splitting procedure can be sensitive to the analysis conditions (i.e. the signal processing procedure used, the presence of noise within the signal, and the spacing of the sensors) and, as a result, produce spurious results. This paper explores this issue and proposes, and analyses, a range of strategies to improve the signal-splitting results. The strategies explored involve the consideration of alternative time- and frequency-domain formulations; the use of filters and wavelet to condition the signal; and processing the time-shifted differenced signal as opposed to the original raw signal. Results are presented for a range of numerical and laboratory systems.
COVID 19 e a violência doméstica. Uma reflexão nos ordenamentos Português e brasileiro.
Authors: Santos Baia Marcelo , Abrão Neto Alexandre , De Moraes Mello Cleyson 
Published: September 2023

Declarada como pandemia pela OMS em março de 2020, a contaminação global pelo coronavírus foi o ponto de partida para que os países alterassem o nível de alerta devido a rápida disseminação do agente causador da COVI-19. Isso ocorreu porque o vírus, ainda sem vacina de ação comprovada disponibilizada para a população, é considerado um agente biológico de alto poder contaminante e atinge o organismo de forma agressiva (UNASUS, 2020).
Contudo, além das particularidades que envolvem a doença e causam graves consequências à saúde do doente, existem outros fatores que também precisam ser discutidos. Para análise, este artigo considera como efeitos secundários e terciários da pandemia da COVID-19, a necessidade de quarentena atingindo um grande número de pessoas e a violência doméstica, consecutivamente, sendo este último foco desta análise (BOND, 2020; ONU, 2020).
A violência doméstica diz respeito a ações criminosas dolosas que causam um efeito prejudicial e nocivo a uma pessoa pertencente a mesma família, ou que vive sob o mesmo teto que o agressor. Segundo dados estatísticos, as maiores vítimas de violência doméstica no mundo são as mulheres e as crianças. Apesar de inicialmente o termo violência doméstica remeter a violência física, existem outras categorias de violência que também se enquadram legalmente nesta tipologia de crime. Entre os tipos de violência doméstica legalmente reconhecida está o estupro, a violência sexual, psicológica e a financeira, o cárcere, entre outros que podem variar tanto de intensidade como de intensidade.
Este artigo busca apresentar uma reflexão acerca do cenário atual da sociedade, tendo como parâmetro os ordenamentos jurídicos brasileiro e português, diante do aumento dos casos de violência doméstica durante a pandemia da COVID-19. Para isso estabeleceu como objetivos específicos abordar a violência doméstica e suas variações; apresentar as estatísticas da violência doméstica no Brasil e em Portugal; e, por fim, comparar as legislações associadas a violência doméstica em ambos os países. Para isso adotou-se como metodologia de pesquisa a revisão de literatura em artigos e dissertações disponibilizadas gratuitamente em língua portuguesa, análise documental e da legislação brasileira e portuguesa.
Impactos na formação dos residentes de enfermagem frente à pandemia de COVID-19: uma revisão integrativa
Authors: Thomaz Júnior Carlos Roberto , Santos Ronan dos , Tonole Renato , Araújo Cláudia Regina Gomes de , Santos Tatiane Araújo dos , Passos Joanir Pereira 
Published: September 2023

Objetivo: descrever as evidências científicas sobre os impactos na formação de residentes de enfermagem durante a pandemia de COVID-19. Método: pesquisa qualitativa do tipo revisão integrativa de literatura orientada pelo acrônimo PICo (Participante, Fenômeno de Interesse e Contexto). Considera-se P – Residentes de enfermagem; I – Impactos na formação e Co – Pandemia de COVID-19. Foram realizadas buscas nas bases de dados PUBMED, EMBASE, CINAHL e LILACS. Seguiu-se os passos metodológicos da identificação do tema e seleção de pesquisa, definição dos critérios de inclusão e exclusão, identificação dos estudos pré-selecionados e selecionados, categorização dos estudos selecionados, análise e interpretação dos resultados e apresentação da revisão/síntese do conhecimento. Resultados: foram selecionados 09 artigos e, a partir da análise de conteúdo de Bardin, foram elencadas 3 categorias: Impactos relacionados à saúde psíquica e fatores estressores (03) artigos; Aspectos ocupacionais e segurança, contágio e fatores correlacionados (2) artigos; Exaustão, cansaço físico, dificuldade no aprendizado e dificuldade de interação (4) artigos. Conclusão: os estudos apontaram que o impacto na formação dos residentes de enfermagem durante o contexto pandêmico afetou primordialmente a esfera da saúde mental de maneira direta e/ou indireta.
Palavras-chaves: Internato e Residência; Enfermagem; Estudantes de Enfermagem; COVID-19; Estresse Psicológico; Ansiedade.
Educação Interprofissional na formação dos profissionais de saúde à luz da Análise Institucional
Authors: Barbosa Alexandra Rodrigues , Mourão Lucia Cardoso , Almeida Ana Clementina Vieira de , Leite Isabel Cristina de Moura , Lima Patrícia Marano 
Published: September 2023

O desafio posto para as universidades e os serviços é atender às complexas e dinâmicas necessidades de saúde, institucionalizando o modelo de atenção do SUS, acompanhado de um processo sólido de reorientação do modelo de formação. Este estudo teve como objetivo apresentar os resultados de uma revisão de literatura sobre a EIP, destacando como a interprofissionalidade, as ações colaborativas e a integração ensino-serviço-comunidade podem favorecer a formação de acadêmicos na Atenção Primária à Saúde. Trata-se de uma pesquisa bibliográfica, com abordagem qualitativa, utilizando o referencial teórico-metodológico da Análise Institucional. Na primeira fase, buscou na Scielo e na Biblioteca Virtual em Saúde artigos sobre a temática a ser abordada, sendo selecionados 9 artigos. Na segunda fase, foram utilizados documentos e manuais que abordam a EIP e o PET-Saúde. Como resultado destacaram-se os movimentos instituídos e instituites presentes nas instituições saúde, educação, formação e práticas em saúde, e que são muitos os obstáculos e desafios a serem enfrentados para romper com as práticas instituídas. Esses necessitam ser rompidas desde o micro espaço das salas de aula e dos ambientes onde se desenvolvem as práticas de cuidado, durante a formação, até o nível macro, ampliando e favorecendo a implantação de novas políticas para a formação de docentes, profissionais de saúde e acadêmicos para o SUS. Espera-se com este estudo, contribuir com as reflexões e debates sobre as necessárias mudanças curriculares e coadunadas com a ampliação de espaços nos serviços para a formação de futuros profissionais de saúde.
Palavras-chave: Educação Interprofissional; Capacitação de Recursos Humanos em Saúde; Atenção Primária à Saúde.
Transtornos mentais comuns entre acadêmicos de enfermagem de Universidade Federal no isolamento social
Authors: Chehab Carolina de Freitas , Silva Jorge Luiz Lima da , Messias Claudia Maria , Dos Santos Maria da Soledade Simeão 
Published: September 2023

A saúde mental abrange a capacidade de enfrentar obstáculos e ser resiliente, lidar com o estresse diário normal, ser capaz de contribuir nas questões sociais e na promoção da paz e estabilidade das comunidades. Os transtornos mentais comuns (TMC) têm importante prevalência, com sintomatologia difusa e pouco detectada em diversos grupos. Estudantes universitários são acometidos por TMC e são, portanto, um grupo populacional de interesse para que o percurso acadêmico seja menos adoecedor e mais proveitoso. Buscou-se conhecer o perfil sociodemográfico e de vida acadêmica dos alunos de enfermagem da Universidade Federal Fluminense (UFF), observando a incidência de TMC, durante a pandemia de covid-19. Materiais e métodos: estudo epidemiológico seccional descritivo e analítico, com associação estatística para analisar a influência do isolamento social nos TMC. Os participantes de pesquisa foram questionados sobre a vida acadêmica e aspectos sociodemográficos. Resultados e Discussão: a prevalência global de suspeição para TMC foi de 71,1%. Sexo feminino apresentou suspeição para TMC com significância estatística (76,8%, p ≤ 0,0001). No quesito vida acadêmica, a qualidade do acesso à internet ('péssima, 100,0%, p = 0,032) e não ter ambiente próprio para estudo (92,6%, p=0,004) também se associaram positivamente com TMC. Considerações finais: a prevalência de suspeição para TMC foi mais frequente no sexo feminino, como visto também em outros estudos com populações universitárias. Ressalta-se a importância de acompanhar de perto a população estudada no âmbito da saúde mental, pois tornar-se-ão profissionais de saúde em breve e cuidarão de outros indivíduos em aspecto global.
Palavras-chave: Estudantes de Enfermagem; Transtornos Mentais Comuns; Pandemia.