bluuebunny/crossref_metadata_2025_split huggingface dataset:
MELELA DI TENGAH ISTANA HOMOPHOBIA REFLEKSI TEORI REKOGNISI AXEL HONNETH PADA KELOMPOK QUEER DI INDONESIA
Authors: Indriani Laillia Dhiah 
Published: August 2023

<div class="WordSection1"><p align="center"><strong>ABSTRAK</strong></p><p align="center"><strong> </strong></p><p>Kehadiran kaum <em>Queer </em>di Indonesia masih terdengar tabu. Padahal, mereka talah ada dari sebelum Indonesia bisa berkata Merdeka. <em>Queer </em>telah menjadi semacam budaya yang juga melekat pada Indonesia. Hal ini tercermin melalui berbagai suku yang nyatanya mengakui keberagaman gender. Namun, seiring berkembangnya waktu dengan berbagai paparan isu, <em>Queer </em>mulai dipaksa hilang dari peradaban Indonesia. Tak jarang, penghilangan ini dilakukan melalui berbagai diskriminasi di ruang publik. Penelitian ini akan membahas bagaimana perjuangan kaum <em>Queer </em>dalam melela di tengah masyarakat <em>homophobia </em>di Indonesia. Adapun teori yang akan digunakan pada penelitian ini adalah teori rekognisi Axel Honneth. Hasil dari penelitian ini menunjukkan bahwa pendiskreditan <em>Queer </em>di Indonesia telah sampai pada ranah kebijakan pemerintahan. Masyarakat yang <em>homophobia </em>dan menjunjung tinggi heteronormatifiti telah membawa diskriminasi besar terhadap mereka yang berbeda. Akhirnya, unsur-unsur kemanusiaan menjadi terabaikan.</p><p><em> </em></p><p><strong>Kata Kunci</strong>: <em>Queer, Homophobia, </em>Rekognisi, Heteronormatifiti.</p><p> </p><p align="center"><strong><em>ABSTRACT</em></strong></p><p align="center"><strong><em> </em></strong></p></div><br clear="all" /><p><em>The presence of queer people in Indonesia is still taboo. In fact, they have existed since before Indonesia could say Merdeka. Queerness has become a kind of culture that is also inherent in Indonesia. This is reflected in various tribes, which in fact recognize gender diversity. However, as time progressed and various issues were exposed, queers began to disappear from Indonesian civilization. Not infrequently, this disappearance is carried out through various discriminations in the public space. This research will discuss the struggle of queers to come out in the midst of a homophobic society in Indonesia. The theory that will be used in this research is Axel Honneth's recognition theory. The results of this study indicate that the discrediting of queers in Indonesia has reached the realm of government policy. A society that is homophobic and upholds heteronormativity has brought great discrimination against those who are different. Finally, the elements of humanity become neglected.</em></p><strong><em>Keywords:</em></strong><em> queer, homophobia, recognition, heteronormative.</em>
Detection of Mycoplasma hominis and Ureaplasma urealyticum in Blood Samples of Recurrent Pregnancy Loss in Women by Polymerase Chain Reaction.
Authors: Chiad Ishraq A. 
Published: August 2023

Background: Genital mycoplasma are implicated in pelvic inflammatory disease, puerperal infection, septic abortion, low birth weight, nongonococcal urethritis and prostatitis as well as spontaneous abortion and infertility in women.
Objective: We aimed to find a relationship between repeated abortions of unknown etiology and caused of Mycoplasma hominis and\or Ureplasma urealyticum.
Methods: one hundred sixty cases, (15-49 years old) with history of recurrent abortion, intrauterine fetal death and\or neonatal death (after exclusion of other factors as cause abortion), and hundred women with normal pregnancy outcome with the same age were chosen as controls. M. homini and U. urealyticum were detected in blood by PCR.
Result: M. homini could be detected in 12\160 (7.5%) in women with pregnancy losses, but was not detected in control group. U. urealyticum could be detected in 64\160 (40%) in patient group and 4\100 (4%) in control group. The rapid detection of M. homini and\or U. urealyticum by PCR in pregnancy loss women could be important and necessary. The detection rate of M. homini and\or U. urealyticum in young women age (20-29 years) was higher than the others. Significant difference was observed in patients with three or four abortions compare with 2 or one abortion in addition to history of adverse outcome.
Conclusion: the role M. homini and\or U. urealyticum in the etiology of pregnancy losses was proposed.
A la espera del bienestar psicológico: resiliencia en épocas de pandemia
Authors: Carbone Carolina Vanessa 
Published: August 2023

En el 2020 el coronavirus generó caos en las sociedades alrededor mundo. Mediante la incrementación de casos de personas infectadas con el virus, los gobiernos tomaron medidas que tarde o temprano, llevaron a realizar cuarentena obligatoria, así como también la educación a distancia, el uso de barbijos al salir a la calle, la distancia social y la comunicación virtual. En su momento, estas medidas fueron de emergencia sanitaria para resguardar a la población, evitar el incremento de contagios y a la vez, evitar un colapso del sistema sanitario, sin embargo, estas han influido negativamente en la socialización de los adolescentes durante la pandemia. Ahora bien, en el presente artículo se busca desarrollar y analizar dos variables: el bienestar psicológico y la resiliencia en tiempos de pandemia especialmente de adolescentes. Este artículo se ha realizado una vez pasado el contexto de pandemia, ya que resulta relevante preguntarse cómo estas medidas implementadas, como así también el momento crítico en el que se encontraba cada país, influía en la salud mental de los adolescentes. Se puede concluir que la pandemia por COVID-19 ha dejado secuelas importantes a nivel psicológico, las cuales actualmente son parte del trabajo de los profesionales de la salud mental.
IMPLEMENTASI RETRIBUSI PELAYANAN PASAR SECARA ELEKTRONIK (E-RETRIBUSI) DI KABUPATEN TEMANGGUNG
Authors: Kurniawan Aditya Hendi , Hamid Muda Setia 
Published: August 2023

This study aims to evaluate the implementation of electronic market service fees (E- Retribution) in Temanggung Regency. The research was conducted at the Office of Cooperatives, Small and Medium Enterprises and Trade, Temanggung Regency in December 2022. This type of research is descriptive qualitative. Data collection techniques using interviews, observation and documentation.The data analysis used is Miles and Huberman's Interactive Data Analysis Model which consists of data reduction, data presentation and conclusion/verification.The research results show that:
The stages in implementing market service fees electronically (E-Retribution) are coordination of parties related to E-Retribution, making E-Retribution applications, making merchant NPWRDs, socializing E-Retribution to market traders, and appointing special officers to carry out assistance and E-Retribution assistance
Obstacles faced in implementing E-Retribution are that the internet network is not optimal, there are frequent disruptions to the E-Retribution application system with MPOS, a balance filling system that is not practical, Standard Operational Procedure (SOP) does not yet exist, application dashboard displays and features are not all presented in the E- Retribution application.
3). Efforts in implementing E-Retribution are coordinating with the Office of Communication and Informatics to handle the internet network, coordinating with E-Retribution application vendors and Bank Jateng to overcome disruptions to the E-Retribution system, E-Retribution SOPs are being prepared and discussed internally by the Service and coordination with parties vendor regarding the addition of data search features and adjustments to the appearance of the E-Retribution application dashboard according to needs so that it will be easier to understand.
Management of Education Financing According to the Qur’an and Hadith
Authors: Winarto Andri , Mahmud Muchammad Eka , Muadin Akhmad 
Published: August 2023

This study aims to determine how the management of education financing according to the Qur'an and Hadith. The research method used is a literature review method sourced from previous studies published in journals, then analyzed and reformulated how to manage education financing according to the Qur'an and Hadith. Based on the results of the analysis, it is known that 1) The input of education financing management from the perspective of the Quran and Hadith is Rabani, namely the management of education financing whose concepts, principles and foundations are taken and concluded from the Quran, which is a holy book for all humans, especially Muslims, which Allah Almighty revealed to the Prophet Muhammad SAW; 2) Output, namely a) management of educational financing perspective of the Quran and Hadith is Ubudiah (mahdhoh worship and ghoiru mahdhoh worship); b) akhlaki, which is having morals (ethics) or being moral. In managing and managing education costs, in addition to being aimed at the success of activities and programs, morals are also needed in its management so as not to cause damage and loss. The akhlaki management of education financing in the Qur'an and Hadith is redacted with the word "la tabkhosū or la tukhsiru."
Intraoperative sensor technology quantifies inter-prosthesis pressure for predicting lower limb alignment after Oxford unicompartmental knee arthroplasty
Authors: Ge Juncheng , Sun Xiaowei , Liu Changquan , Zhang Qidong , Wang Bailiang , Guo Wanshou 
Published: August 2023

Purpose: The aim of this study is to quantify inter-prosthetic pressures at different knee angles in Oxford unicompartmental knee arthroplasty (OUKA) and its correlation with postoperative lower limb alignment.Methods: This study included 101 patients (122 knees) who underwent OUKA from March 2022 to July 2022. The previously designed matrix flexible force sensor was used to measure the inter-prosthesis pressure of different knee joint angles during the UKA operation, and the force variation trend and gap balance difference were obtained. The correlation between inter-prosthesis pressure and postoperative lower limb alignment index including hip-knee-ankle angle (HKAA) and posterior tibial slope (PTS) was analyzed. The effect of PTS change (ΔPTS) on the inter-prosthesis pressure and the range of motion (ROM) of the knee joint was analyzed. Radiographic and short-term clinical outcomes of included patients were assessed.Results: The inter-prosthesis pressure of the different knee joint angles during the operation was not consistent. The mean inter-prosthesis pressure and gap balance difference were 73.68.28 ± 41.65N and 36.48 ± 20.58N. The inter-prosthesis pressure at 0° and 20° was positively correlated with postoperative HKAA (p &lt; 0.001). ΔPTS was positively correlated with the pressure at the end of knee extension and negatively correlated with the pressure at the end of knee flexion (p &lt; 0.001). The HKAA, ROM, degree of fixed knee flexion deformity, and knee society score of the included patients were significantly improved compared with those before the operation (p &lt; 0.001).Conclusion: The inter-prosthesis pressure measured at the knee extension position can predict postoperative HKAA to some degree. Changes in PTS will affect the inter-prosthesis pressure at the end of flexion and end of knee extension, but this change is not related to the range of motion of the knee joint.
Identifying potential circulating miRNA biomarkers for the diagnosis and prediction of ovarian cancer using machine-learning approach: application of Boruta
Authors: Hamidi Farzaneh , Gilani Neda , Arabi Belaghi Reza , Yaghoobi Hanif , Babaei Esmaeil , Sarbakhsh Parvin , Malakouti Jamileh 
Published: August 2023

IntroductionIn gynecologic oncology, ovarian cancer is a great clinical challenge. Because of the lack of typical symptoms and effective biomarkers for noninvasive screening, most patients develop advanced-stage ovarian cancer by the time of diagnosis. MicroRNAs (miRNAs) are a type of non-coding RNA molecule that has been linked to human cancers. Specifying diagnostic biomarkers to determine non-cancer and cancer samples is difficult.MethodsBy using Boruta, a novel random forest-based feature selection in the machine-learning techniques, we aimed to identify biomarkers associated with ovarian cancer using cancerous and non-cancer samples from the Gene Expression Omnibus (GEO) database: GSE106817. In this study, we used two independent GEO data sets as external validation, including GSE113486 and GSE113740. We utilized five state-of-the-art machine-learning algorithms for classification: logistic regression, random forest, decision trees, artificial neural networks, and XGBoost.ResultsFour models discovered in GSE113486 had an AUC of 100%, three in GSE113740 with AUC of over 94%, and four in GSE113486 with AUC of over 94%. We identified 10 miRNAs to distinguish ovarian cancer cases from normal controls: hsa-miR-1290, hsa-miR-1233-5p, hsa-miR-1914-5p, hsa-miR-1469, hsa-miR-4675, hsa-miR-1228-5p, hsa-miR-3184-5p, hsa-miR-6784-5p, hsa-miR-6800-5p, and hsa-miR-5100. Our findings suggest that miRNAs could be used as possible biomarkers for ovarian cancer screening, for possible intervention.
Indian Red Jungle fowl reveals a genetic relationship with South East Asian Red Jungle fowl and Indian native chicken breeds as evidenced through whole mitochondrial genome sequences
Authors: Kanakachari M. , Chatterjee R. N. , Reddy M. R. , Dange M. , Bhattacharya T. K. 
Published: August 2023

Background: Native chickens are dispersed in a wide geographical range and have hereditary assets that are kept by farmers for various purposes. Mitochondrial DNA (mtDNA) is a widely utilized marker in molecular studies because of its quick advancement, matrilineal legacy, and simple molecular structure.Method and Results: We performed NGS sequencing to investigate mitochondrial genomes and to evaluate the hereditary connections, diversity, and measure of gene stream estimation in Indian native chicken breeds and Red Jungle fowl. The chicken breeds were genotyped using the D-loop region and 23 haplotypes were identified. When compared to Indian native breeds, more haplotypes were identified in the NADH dehydrogenase subunits, Cytochrome c oxidase, Cytochrome b, ATP synthase subunit 6, and Ribosomal RNA genes. The phylogenetic examination indicated that the analyzed chicken breeds were divided into six significant clades, namely A, B, C, D, E, and F, of which the F clade indicated the domestication of chicken breeds in India. Additionally, our work affirmed that the Indian Red Jungle Fowl is the origin for both reference Red Jungle Fowl as well as all Indian breeds, which is reflected in the dendrogram as well as network analysis based on the whole mtDNA and D-loop region. Indian Red Jungle Fowl is distributed as an outgroup, suggesting that this ancestry was reciprocally monophyletic.Conclusion: The mtDNA sequences of Indian native chickens provided novel insights into adaptation mechanisms and the significance of important mtDNA variations in understanding the maternal lineages of native birds.
Identifying immune cell infiltration and effective diagnostic biomarkers in Crohn’s disease by bioinformatics analysis
Authors: Huang Rong , Wang Wenjia , Chen Ziyi , Chai Jing , Qi Qin , Zheng Handan , Chen Bingli , Wu Huangan , Liu Huirong 
Published: August 2023

BackgroundCrohn’s disease (CD) has an increasing incidence and prevalence worldwide. It is currently believed that both the onset and progression of the disease are closely related to immune system imbalance and the infiltration of immune cells. The aim of this study was to investigate the molecular immune mechanisms associated with CD and its fibrosis through bioinformatics analysis.MethodsThree datasets from the Gene Expression Omnibus data base (GEO) were downloaded for data analysis and validation. Single sample gene enrichment analysis (ssGSEA) was used to evaluate the infiltration of immune cells in CD samples. Immune cell types with significant differences were identified by Wilcoxon test and Least Absolute Shrinkage and Selection Operator (LASSO) regression analysis. Differentially expressed genes (DEGs) were screened and then subjected to Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) functional correlation analysis, as well as protein-protein interaction (PPI) network analysis. The cytoHubba program and the GSE75214 dataset were used to screen for hub genes and plot Receiver operating characteristic (ROC)curves to screen for possible biomarkers of CD based on diagnostic efficacy. The hub genes of CD were correlated with five significantly different immune cells. In addition, validation was performed by real time quantitative PCR (RT-qPCR) experiments in colonic tissue of CD intestinal fibrosis rats to further identify hub genes that are more related to CD intestinal fibrosis.ResultsThe DEGs were analyzed separately by 10 algorithms and narrowed down to 9 DEGs after taking the intersection. 4 hub genes were further screened by the GSE75214 validation set, namely COL1A1, CXCL10, MMP2 and FGF2. COL1A1 has the highest specificity and sensitivity for the diagnosis of CD and is considered to have the potential to diagnose CD. Five immune cells with significant differences were screened between CD and health controls (HC). Through the correlation analysis between five kinds of immune cells and four biomarkers, it was found that CXCL10 was positively correlated with activated dendritic cells, effector memory CD8+ T cells. MMP2 was positively correlated with activated dendritic cells, gamma delta T cells (γδ T) and mast cells. MMP2 and COL1A1 were significantly increased in colon tissue of CD fibrosis rats.ConclusionMMP2, COL1A1, CXCL10 and FGF2 can be used as hub genes for CD. Among them, COL1A1 can be used as a biomarker for the diagnosis of CD. MMP2 and CXCL10 may be involved in the development and progression of CD by regulating activated dendritic cell, effector memory CD8+ T cell, γδ T cell and mast cell. In addition, MMP2 and COL1A1 may be more closely related to CD intestinal fibrosis.
Identification of cuproptosis and immune-related gene prognostic signature in lung adenocarcinoma
Authors: Zhang Wentao , Qu Haizeng , Ma Xiaoqing , Li Liang , Wei Yanjun , Wang Ye , Zeng Renya , Nie Yuanliu , Zhang Chenggui , Yin Ke , Zhou Fengge , Yang Zhe 
Published: August 2023

BackgroundCuproptosis is a novel form of programmed cell death that differs from other types such as pyroptosis, ferroptosis, and autophagy. It is a promising new target for cancer therapy. Additionally, immune-related genes play a crucial role in cancer progression and patient prognosis. Therefore, our study aimed to create a survival prediction model for lung adenocarcinoma patients based on cuproptosis and immune-related genes. This model can be utilized to enhance personalized treatment for patients.MethodsRNA sequencing (RNA-seq) data of lung adenocarcinoma (LUAD) patients were collected from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. The levels of immune cell infiltration in the GSE68465 cohort were determined using gene set variation analysis (GSVA), and immune-related genes (IRGs) were identified using weighted gene coexpression network analysis (WGCNA). Additionally, cuproptosis-related genes (CRGs) were identified using unsupervised clustering. Univariate COX regression analysis and least absolute shrinkage selection operator (LASSO) regression analysis were performed to develop a risk prognostic model for cuproptosis and immune-related genes (CIRGs), which was subsequently validated. Various algorithms were utilized to explore the relationship between risk scores and immune infiltration levels, and model genes were analyzed based on single-cell sequencing. Finally, the expression of signature genes was confirmed through quantitative real-time PCR (qRT-PCR), immunohistochemistry (IHC), and Western blotting (WB).ResultsWe have identified 5 Oncogenic Driver Genes namely CD79B, PEBP1, PTK2B, STXBP1, and ZNF671, and developed proportional hazards regression models. The results of the study indicate significantly reduced survival rates in both the training and validation sets among the high-risk group. Additionally, the high-risk group displayed lower levels of immune cell infiltration and expression of immune checkpoint compared to the low-risk group.
The role of neutrophil percentage to albumin ratio in predicting 1-year mortality in elderly patients with hip fracture and external validation
Authors: Jiao Songsong , Zhou Jiangfei , Feng Zhencheng , Huang Jian , Chen Lihong , Li Zhiwu , Meng Qingqi 
Published: August 2023

ObjectivesThis study aimed to investigate the association between the neutrophil percentage to albumin ratio (NPAR) on the day of admission and mortality 1 year after surgery in elderly patients with hip fractures.MethodsClinical characteristics and blood markers of inflammation were retrospectively collected from October 2016 to January 2022 in elderly patients with hip fractures at two different regional tertiary medical centers. It is divided into a training set and an external validation set. Multivariate Nomogram models such as NPAR were constructed using the least absolute shrinkage and selection operator (LASSO) regression results and multi-factor logistic regression analysis. In addition, multivariate Cox regression analysis and Kaplan-Meier survival curves were used to explore the relationship between NPAR values and mortality within 1 year in elderly patients with hip fractures. The predictive performance of the Nomogram was evaluated using the concordance index (C Index) and receiver operating characteristic curve (ROC) and validated by Bootstrap, Hosmer-Lemesow goodness of fit test, calibration curve, decision curve, and clinical impact curve analysis.ResultsThe study included data from 1179 (mean age, 80.34 ± 8.06 years; 61.4[52.1%] male) patients from the Guangzhou Red Cross Hospital affiliated with Jinan University and 476 (mean age, 81.18 ± 8.33 years; 233 [48.9%] male) patients from the Xiaogan Central Hospital affiliated with Wuhan University of Science and Technology. The results showed that NPAR has good sensitivity and specificity in assessing patients’ prognosis 1 year after surgery. Multivariate logistic regression models based on influencing factors such as NPAR have good discrimination and calibration ability (AUC=0.942, 95% CI:0.927-0.955; Hosmer-Lemeshow test: P &gt;0.05). Kaplan-Meier survival curves for the training and validation sets showed that patients in the high NPAR group had a higher mortality rate at 1 year compared to the low NPAR group (P&lt; 0.001). Multivariate Cox regression showed that high NPAR values were an independent risk factor for death within 1 year in elderly hip fracture patients (P&lt; 0.001, HR =2.38,95%CI:1.84-3.08).ConclusionOur study showed that NPAR levels were significantly higher in patients who died within 1 year after surgery in both the training and validation sets. NPAR has good clinical value in assessing 1-year postoperative prognosis in elderly patients with hip fractures.