bluuebunny/crossref_metadata_2025_split huggingface dataset:
Application of electrocoagulation process for the removal of chloroquine from an aqueous solution
Authors: Elkacmi Reda , Zahnoune Rajaa , El Amri Radouane , Boudouch Otmane 
Published: March 2023

AbstractUsing chloroquine (CQ) as a provisional treatment for COVID-19 patients generates more pharmaceutical waste, posing a potential environmental threat. The present study evaluates the feasibility of the electrocoagulation (EC) process in removing CQ from an aqueous solution. The experiment was performed in a laboratory-scale stirred tank reactor (STR). The effects of operating conditions were investigated. Equilibrium and kinetic experiments were also performed to describe CQ adsorption. The results showed that increasing both the applied current density and the EC reaction time increases the removal efficiency of CQ. The results showed that 95% of CQ removal efficiency was achieved at a current density of 66.89 mA/cm2, 600 rpm of agitation rate, 60 min of electrolysis time, an initial CQ concentration of 3 mg/L, and a pH of 6.5. For equilibrium and kinetic studies, the Langmuir isotherm and the pseudo-second-order provided the best fit to the experimental data. The optimal operating conditions led to a specific amount of dissolved aluminum electrodes and a specific energy consumption of 0.228 kg/m3 and 12.243 kWh/m3. These results suggest that the EC process is an excellent tool for effectively degrading CQ from wastewater with a low operating cost (2.48 USD/m3).
Pulmonary Adenocarcinoma Patient with Complex Mutations on EGFR
Benefits from Furmonertinib after Acquiring Gefitinib Resistance: A Case
Report
Authors: Wu Guixian , Chen Qian , Lv Dongqing , Lin Ling , Huang Jing 
Published: March 2023

Background:
A 62-year-old woman was diagnosed with pulmonary adenocarcinoma with
stage IV. Genetic testing at the initial treatment showed EGFR L858R positive. After being treated
with gefitinib, persistent 2 years disease progression occurred due to drug resistance. The genetic
testing showed that EGFR L858R was eliminated, while a rare rare complex mutation of
L861Q/G719X appeared. After 160 mg furmonertinib was treated for 1 month, the primary tumor
regressed and the intracranial lesions disappeared. The patient has achieved progression-free survival
(PFS) for more than 20 months.

Case Presentation:
A 62-year-old woman was diagnosed with pulmonary adenocarcinoma with
stage IV. Genetic testing at the initial treatment showed EGFR L858R positive. After being treated
with gefitinib, persistent 2 years disease progression occurred due to drug resistance. The genetic
testing showed that EGFR L858R was eliminated, while a rare rare complex mutation of
L861Q/G719X appeared. After 160 mg furmonertinib was treated for 1 month, the primary tumor
regressed and the intracranial lesions disappeared. The patient has achieved progression-free survival
(PFS) for more than 20 months.

Conclusion:
Pulmonary adenocarcinoma with rare rare complex mutations in EGFR induced by
gefitinib resistance and disease progression might benefit from furmonertinib treatment.
Protective Effect of Curcumin and Nanocurcumin on Sperm Parameters
and Oxidant-antioxidants System of Rat Testis in Aluminium Phosphide
Subacute Poisoning
Authors: Ghasemi Hadi , Ranjbar Akram , Kheiripour Nejat , Shateri Hossein , Sameri Amirhossein 
Published: March 2023

Objective:
Aluminum phosphide (AlP) as an effective pesticide may contribute to oxidative
stress and adversely influence sperm parameters. This study aimed to investigate the protective role of
curcumin and nanocurcumin on oxidative damage in the testis of rats with AlP toxicity.

Methods:
A total of 42 adult male Wistar rats were equally randomized into the following study
groups (n=7): Control, Control+Curcumin, Control+Nanocurcumin, AlP, AlP+Curcumin, and
AlP+Nanocurcumin. The testis tissue was used to investigate the levels of testicular malondialdehyde
(MDA), total oxidant status (TOS), total antioxidant capacity (TAC), and reduced glutathione (GSH) as
well as the Catalase (CAT) and superoxide dismutase (SOD) enzyme activity. Epididymal sperm was
used to perform sperm analysis.

Results:
AlP administration led to a significant increase in MDA, and TOS levels and also markedly
decreased the SOD activity and the levels of TAC and GSH in testis tissue (p<0.001). Moreover, the
motility and viability of sperms were significantly reduced (p<0.001). Curcumin and Nanocurcumin coadministration
with AlP remarkably decreased the MDA and TOS level (p<0.001) and significantly increased
the GSH and TAC levels as well as the activity of SOD in AlP intoxicated groups (p<0.001).
Our findings demonstrated that Nanocurcumin administration has significantly enhanced the sperm
quality in AlP intoxicated rats as compared to the control group (p<0.001).

Conclusion:
According to the results of this study, Curcumin as a potential antioxidant could be an effective
attenuative agent against AlP-induced oxidative damage in testis, especially when it is used in
encapsulated form, nanocurcumin.
Монгол орны төвийн бүсийн аймгуудын хөрсний цацраг идэвх
Authors: Ц. Эрхэмбаяр  , Н. Норов  , Г. Хүүхэнхүү  , М. Алтангэрэл  
Published: March 2023

Төвийн бүсийн аймгуудын төв болон сумдын газрын хөрсөнд цацраг идэвхт тунадас хэлбэрээр буусан цези-137ийн хуримтлал, хөрсөн дэх 238U, 232Th, 226Ra, 40K зэрэг байгалийн цацраг идэвхт изотопуудын хувийн идэвхийг тодорхойлж, манай орны бусад аймгууд болон дэлхийн дундажтай харьцуулж үзэв.
Possibility of direct rapid determination of inorganic contaminant elements in paints by LA-ICP-MS method
Authors: R Galbadrakh , K Simon , T Myanganbaatar , B Ulziitogtokh , L Enkhtur , G Woerner 
Published: March 2023

In this work content of inorganic major and trace elements were directly determined in produced in China, Russia, and Germany household use purpose oil, асгуI, and ochre paint samples using laser ablation-inductively coupled plasma-mass spectroscopy (LA_ICP_MS) technique. A sample preparation was simple and rapid: an oil and acryl paint droplets were dried on glass substrate for several hours on a hot plate at 60° C and few mg ochre paint powder samples were solidified with pure paraffin wax on the glass substrate. Dried oil and acryl paint droplets were ablated locally, drilling the hole way, while ochre paint powders were ablated using surface rastering method. Contents of inorganic elements were calculated using the NIST 610 glassy standard sample as the reference. Parallel determination results of lead and chromium in oil paint samples by atomic absorption technique correlates with that of by LA_ICP_MS acceptably (correlation coefficient for lead is 0.85 and for chromium is 0.95). Because of sample organic - reference inorganic matrix difference, the measured by the LA_ICP_MS content of each element must be adjusted being multiplied in some quantity, value of which are different for each element. For lead and chromium value of the quantity found correspondingly as 6.4 and 9.3. The average relative standard deviation (RSD) of measured content of the mostly high content elements Ca, Al, Mn, Pb, Sr, S, Mg, Fe, Sb, Na, Co, Si, Zn, Cu, P, Y, K, CI, Ce, and La is less than 10%, the RSD for elements Ti, Cr, Sn, Ba, Zr, Rb lies between 10 and 20%, and the RSD for trace elements Gd, Nb, Sc, V, U. Pr, Ni, Ga, Eu, As, Th B, Mo, Cd, Li lies in interval from 20 to 50 %. High level of concentration 309 - 24300 ppm for lead, 950- 3134 ppm for chromium are detected by LA-ICP-MS method in samples of red, yellow and green color oil paints produced in China and bestselling in Mongolia certain brand products. Up to 1900 ppm alarming high content of arsenic is tovnd in the Chinese origin yellowish red, brown red color ochre paints. As shows our measurements, the LA-ICP-MS method is possible to use as alternative rapid semi-quantitive detection method with acceptable accuracy and precision for basic inorganic additives in oil, acryl and ochre paints using glassy standard sample.
First-principles study of crystal and electronic structures and magnetic property for NaFeCr(WO4)2 compounds
Authors: N Tsogbadrakh , L Nyam-Ochir , Kh Tsookhuu , S.C Hong 
Published: March 2023

We have first studied the crystal and electronic structures, and magnetic property for sodium double tungstate NaFexCr 1-x(WO 4)2 (x =0, 0.50 and 1.0) compounds using the plane wave self-consistent method within the framework of density functional theory (DFT). We show that the ground state of sodium double tungstate compounds is the antiferromagnetic (AFM) state. We emphasize that the AFM coupling on the bc plane is generated by the 90 o superexchange mechanism. While the AFM coupling of the long-range magnetic interaction between the layers along the a - axis is generated by the Na mediated super - superexchange mechanism.
Meningkatkan Potensi Berbahasa Anak Menggunakan Permainan Tradisional di TK Kemala-B Jambi
Authors: Pudjaningsih Wiwik 
Published: March 2023

Abstrak
Penelitian ini bertujuan mendeskripsikan penggunaan permainan tradisional untuk meningkatkan kualitas proses dan hasil pembelajaran berbahasa anak Taman Kanak-kanak Kemala Bayangkari Jambi (TK-KBJ). Penelitian ini menggunakan penelitian tindakan kelas (PTK). Subjek penelitian guru dan anak Semester I Tahun Pelajaran 2019/2020 TK-KBJ. Kegiatan pembelajaran terdiri atas tiga siklus, masing-masing terdiri atas perencanaan, pelaksanaan tindakan, pengamatan, dan refleksi. Instrumen penelitian: peneliti sendiri, lembar pengamatan, pedoman wawancara, catatan lapangan, dan alat perekam gambar-suara. Teknik analisis data penelitian secara kualitatif dan kuantitatif. Hasil penelitian ini penggunaan permainan tradisional dapat meningkatkan kualitas proses dan hasil pembelajaran bahasa anak TK-KBJ. Kualitas proses, sebagai berikut: skor pada Siklus-1: 2,34, kualitasnya kurang baik (KB); Siklus-2: 3,40, kualitasnya cukup baik (CB); dan Siklus-3: 4,39, kualitasnya: baik (B). Kualitas hasil potensi berbahasa anak, skor pada Siklus-1: 0,50, kualitasnya belum berkembang (BB); Siklus-2: 1,16, kualitasnya mulai berkembang (MB); dan Siklus-3: 2,00, kualitasnya berkembang sesuai harapan (BSH).

Kata kunci: pembelajaran, permainan tradisional, potensi berbahasa anak

Abstract
This study aims to describe the use of traditional games to improve the quality of the process and learning outcomes of children's language learning at Kemala Bayangkari Kindergarten Jambi (TK-KBJ). This research uses classroom action research (CAR). The research subjects were teachers and children in the first semester of the 2019/2020 school year TK-KBJ. Learning activities consist of three cycles, each consisting of planning, implementing actions, observing, and reflecting. Research instruments: the researcher himself, observation sheets, interview guides, field notes, and a picture-sound recorder. Research data analysis techniques are qualitative and quantitative. The results of this study using traditional games can improve the quality of the process and learning outcomes of children's language learning in Kindergarten-KBJ. Process quality, as follows: score in Cycle-1: 2.34, poor quality (KB); Cycle-2: 3.40, the quality is quite good (CB); and Cycle-3: 4.39, quality: good (B). The quality of the child's language potential results, the score in Cycle-1: 0.50, the quality is not yet developed (BB); Cycle-2: 1.16, the quality starts to develop (MB); and Cycle-3: 2.00, the quality is developing as expected (BSH).
Keywords: learning, traditional games, children's language potential.
Development and Validation of a Diabetic Retinopathy Risk Stratification Algorithm
Authors: Tarasewicz Dariusz , Karter Andrew J. , Pimentel Noel , Moffet Howard H. , K. Thai Khanh , Schlessinger David , Sofrygin Oleg , Melles Ronald B. 
Published: March 2023

<p> </p>
<p>OBJECTIVE: Although diabetic retinopathy is a leading cause of blindness worldwide, diabetes-related blindness can be prevented through effective screening, detection and treatment of disease. The study goal was to develop risk stratification algorithms for the onset of retinal complications of diabetes, including proliferative diabetic retinopathy, referable retinopathy and macular edema.</p>
<p>RESEARCH DESIGN and METHODS: Retrospective cohort analysis of patients from the Kaiser Permanente Northern California Diabetes Registry who had no evidence of diabetic retinopathy at a baseline diabetic retinopathy screening during 2008-2020. Machine learning and logistic regression prediction models for onset of proliferative diabetic retinopathy, diabetic macular edema and referable retinopathy detected through routine screening were trained and internally validated. Model performance was assessed using area under the curve (AUC) metrics.</p>
<p>RESULTS: The study cohort (N=276,794) was 51.9 % male and 42.1% white. Mean (±SD) age at baseline was 60.0 (±13.1) years. A machine learning XGBoost algorithm was effective in identifying patients who developed proliferative diabetic retinopathy (AUC 0.86; 95% CI, 0.86-0.87), diabetic macular edema (AUC 0.76; 95%CI, 0.75-0.77) and referable retinopathy (AUC 0.78; 95% CI, 0.78-0.79). Similar results were found using a simpler 9-covariate logistic regression model: proliferative diabetic retinopathy (AUC 0.82; 95% CI, 0.80-0.83), diabetic macular edema (AUC 0.73; 95% CI, 0.72-0.74) and referable retinopathy (AUC 0.75; 95% CI, 0.75-0.76).</p>
<p>CONCLUSIONS: Relatively simple logistic regression models using 9 readily available clinical variables can be used to rank order patients for onset of diabetic eye disease and thereby more efficiently prioritize and target screening for at risk patients. </p>
Effect of Ceramic Conditioners on Surface Morphology, Roughness, Contact Angle, Adhesion, Microstructure, and Composition of CAD/CAM Ceramics
Authors: Oliveira LT , de Castro EF , Azevedo VLB , de Andrade OS , Faraoni JJ , Palma-Dibb RG , Dias CTS , Giannini M 
Published: March 2023

SUMMARY
The objective of this study was to investigate the effect of surface treatments in maximum profile valley depth (Rv), surface roughness (Sa), contact angle (Ca), shear bond strength (SBS) of a light-cured resin cement, microstructure, and composition of two CAD/CAM ceramics: Cerec Blocs/Dentsply Sirona (feldspathic - FEL) and Empress CAD/Ivoclar Vivadent (leucite-reinforced - LEU). The ceramic specimens were submitted to six surface treatments: (1) 5% hydrofluoric acid (HF) – 20 seconds; (2) 5% HF – 60 seconds; (3) 10% HF – 20 seconds; (4) 10% HF – 60 seconds; (5) self-etching ceramic primer (MEP) – 20 seconds; and (6) MEP – 60 seconds. Specimens treated with HF received silane application for 1 minute. Rv and Sa were evaluated in a confocal laser microscope (n=10) and the Ca in a goniometer (n=6). For the SBS test, two resin cement cylinders were bonded to each specimen, one tested after 24 hours in distilled water storage (37°C) and the other after one year (n=10). The microstructures and compositions were analyzed by scanning electron microscopy (SEM) and energy dispersive x-ray spectroscopy (EDS) (n=4). Rv, Sa, and Ca data were analyzed by two-way ANOVA, and the SBS data by three-way ANOVA, all followed by post-hoc Tukey’s test (α=0.05). Results: Surface treatments with HF always produced higher Rv and Sa, and lower Ca than MEP 60s for both ceramics. After 1-year water storage, FEL ceramic treated with MEP for 60 seconds produced higher SBS values than HF treatments, whereas for LEU ceramic there were no differences among treatments. Application of MEP for 20 or 60 seconds produced no difference in Rv, Sa, Ca, and SBS for both ceramics. Surface treatments produced considerable differences in ceramic topography, but subtle ones in composition, for both ceramics. Conclusions: The results indicated that for FEL ceramic, MEP application for 60 seconds yielded higher SBS compared with HF etching, while for LEU ceramic the surface treatments did not influence the SBS results.
PEGUNGKAPAN BIODIVERSITY PADA PT ADHI KARYA
Authors: Hamsir Ainul Fikri , Muchlis Saiful , Fadhilatunisa Della 
Published: March 2023

Abstract, The purpose of this study is to look at the disclosure and meaning of biodiversity accounting in developer companies through semiotic analysis of the sustainability report of PT. ADHI KARYA 2020. This research is a qualitative type with data analysis method, namely semiotics to see biodiversity accounting disclosures in developer companies. The data used is the sustainability report of PT. ADHI KARYA in 2020 which was obtained from the company's official website. This study conducted an in-depth study with semiotic analysis of the disclosure of biodiversity in the sustainability report of PT. ADHI KARYA. The results of this study indicate that PT. ADHI KARYA's disclosure of biodiversity in its role to participate in maintaining biodiversity status clearly explains the company's operations and the impact of these activities. However, ADHI still maintains the trust of report users by providing solutions after problems arise. This is considered effective in maintaining the trust of report users.
Abstrak, Tujuan penelitian ini untuk melihat pengungkapan dan pemaknaan akuntansi biodiversity pada perusahaan developer melalui analisis semiotika terhadap sustainbility report PT. ADHI KARYA 2020. Penelitian ini berjenis kualitatif dengan metode analisis data yaitu semiotika untuk melihatpengungkapan akuntansi biodiversity pada perusahaan developer. Data yang digunakan yaitu sustainbility report PT. ADHI KARYA tahun 2020 yang diperoleh dari situs web resmi perusahaan. Penelitian ini melakukan kajian mendalam dengan analisis semiotika atas pengungkapan biodiversity pada sustainbility report PT. ADHI KARYA. Hasil penelitian ini menunjukkan bahwa pengungkapan biodiversity PT. ADHI KARYA dalam perannya untuk turut serta menjaga status biodiversitas menjelaskan secara gamblang mengenai operasioal perusahaannya berikut dampak yang ditimbulkan dari aktivitas tersebut. Namun, ADHI tetap menjaga kepercayaan pengguna laporan dengan menyediakan solusi setelah adanya permasalahan yang muncul. Hal ini dinilai efektif dalam menjaga kepercayaan pengguna laporan.
REKONSTRUKSI PEMAHAMAN “PEREMPUAN DICIPTAKAN DARI TULANG RUSUK “(Analis pendekatan intertekstual)
Authors: Wangsa Fadhlina Arief , Bunganegara Muadilah Hs. 
Published: March 2023

Perempuan merupakan salahsatu makhluk mulia yang diciptakan oleh Allah swt. yang hak dan kewajiban disetarakan dengan laki-laki dihadapan penciptanya. Akan tetapi, sejak zaman pra Islam perempuan seringkali dianggap rendah dan lemah, terkadang ketika terlahir bayi perempuan maka akan dikubur hidup-hidup karena dianggap sebagai aib keluarga, dan hal demikian berubah ketika datangnya ajaran Islam. Penciptaan perempuan telah disebutkan didalam sebuah hadis bahwa “perempuan itu tercipta dari tulang rusuk”. Hal demikian memberikan pengaruh kepada perempuan yang terkadang diperlakukan seenaknya oleh lelaki, karena merasa laki-laki lebih unggul daripada perempuan. Akan tetapi, pada zaman dahulu sampai sekarang, manusia keliru memaknai hadis tersebut. Sehingga, sangat perlu mendeskripsikan makna hadis “perempuan diciptakan dari tulang rusuk”, agar perempuan-perempuan memiliki derajat yang sama dengan lelaki, yaitu dapat menjalankan hak dan kodratnya dengan baik. Penelitian ini menggunakan metode kualitatif melalui analisis pendekatan intertekstual, yaitu mengumpulkan informasi dari beberapa literature yang relevan agar dapat dibuktikan keakuratan suatu penelitian, dan tidak terjadi pemahaman yang keliru terhadap pemahaman hadis. Dengan demikian, ditengah banyaknya manusia yang keliru terhadap pemaknaan hadis tersebut dan banyaknya kaum perempuan yang dianggap rendah, penelitian ini hadir sebagai upaya merekonstruksi pemahaman yang terkandung dari hadis “perempuan tercipta dari tulang rusuk”. Makna hadis tersebut ialah sifat wanita yang seperti tulang rusuk, yaitu lemah lembut. Sehingga dengan mengetahui makna hadis tersebut, tidak ada lagi perlakuan seenaknya kepada perempuan, sehingga laki-laki pun lebih menghargai sekaligus menghormati wanita melalui rahmat ajaran Islam yang senantiasa disebarkan, salahsatunya penerapan keadilan antara laki-laki dan perempuan sesuai hak dan kodratnya.
IMPLEMENTASI METODE CERITA ISLAMI DALAM MENANAMKAN AKHLAK ISLAMI PADA KELAS III SD PERSITIM I KUPANG
Authors: Nurdiana Nurdiana - 
Published: March 2023

AbstrakPenelitian ini bertujuan untuk mengambarkan mengenai Akhlak Islami pada siswa kelas III SD Persitim I Kupang dengan melalui implementasi cerita Islami, yang dilakukan sebagai upaya memperkaya pengetahuan dalam bidang keislaman mengenai akhlak islami dengan implementasi metode cerita islami. Penelitian ini adalah penelitian lapangan (field research) menggunakan jenis penelitian deskriptif kualitatif dengan pendekatan sejarah, filosopy, psikologi, teologi, sosial dan budaya. Teknik pengumpulan adalah observasi, wawancara, dan dokumentasi. Hasil penelitian ini menunjukkan bahwa implementasi metode cerita Islami dalam menanamkan Akhlak Islami pada siswa kelas III SD Persitim I Kupang, ada beberapa faktor yaitu faktor lingkungan keluarga, orang tua adalah pendidik yang pertama dalam lingkungan keluarga. faktor lingkungan masyarakat. faktor lingkungan sekolah, Guru di sekolah sebagai pendidik yang mengarahkan peserta didik agar menjadi manusia yang berakhlak kulkarimah atau budi pekerti mulia, sebab di sekolah adalah wadah atau tempat untuk pembinaan dan penanaman akhlak yang Islami sehingga peserta didik dapat berperilaku baik dengan Guru, orang tua, teman dan lain-lain. Keywords; Implementasi, Metode Cerita Islami dan Akhlak Islami AbstractThis study aims to describe Islamic morals in Class III SD Persitim I Kupang through the implementation of Islamic stories, which are carried out as an effort to enrich knowledge in the Islamic field regarding Islamic morals by implementing the Islamic story method. This research is field research using qualitative descriptive research with history, philosopy, psychological, theological, social and cultural approaches. The collection techniques are observation, interview, and documentation. The results of this study indicate that the implementation of the Islamic story method in instilling Islamic Morals in Class III SD Persitim I Kupang, there are several factors, namely family environmental factors, parents are the first educators in the family environment. community environmental factors. school environmental factors, teachers in schools as educators who direct students to become human beings with noble character or noble character, because at school is a place or place for guidance and cultivation of Islamic morals so that students can behave well with teachers, parents, friends and others. Keywords: Implementation, Islamic Stories Method and Islamic Morals
MAQAM CINTA DALAM PANDANGAN AL GHAZALY
Authors: Rauf Rusmin Abdul 
Published: March 2023

Artikel ini akan mendiskusikan tentang konsep cinta yang disampaikan oleh Imam Al Ghazali. Imam al Ghazali merupakan salah seorang pemikir muslim yang sangat berpengaruh. Dalam konsep kebahagiaan beliau menekankan pentingnya cinta dalam meraih kebahagiaan. Bahkan beliau mengatakan bahwa hakikat dari agama Islam adalah cinta kepada Allah Swt. Penelitian ini menemukan bahwa al Ghazali membagi cinta kepada beberapa bagian di antaranya, cinta kepada diri sendiri, kepada orang yang baik hingga kepada cinta yang bersifat microkosmos tentang kesesuaian dengan jiwa manusia. Dalam hal ini, al Ghazali telah memberikan berbagai argumen untuk menguatkan tesis beliau tersebut. Selain itu, beliau juga telah menjelaskan hal-hal yang menguatkan cinta dan tanda-tanda orang yang cinta kepada Allah.