bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative Study of Financial Soundness of State and Private Banks in Indonesia
Authors: Rahmah Miladiatur , Retnasih Nora Ria 
Published: June 2023

This study aims to investigate the impact of bank soundness on the return on assets (ROA) experienced by state and private banks over the 2016-2022 fiscal quarters. In this study, a quantitative research method employing secondary data obtained through the official website of the OJK (Financial Services Authority) was used as the research methodology. For this investigation, the panel data regression analysis carried out in EViews 9 was the analytical tool. According to research on state banks, the CAR and LDR variables have only a partially significant effect on ROA. Notwithstanding this, ROA is significantly influenced by the NPL and NIM variables. On the other hand, private banks provide some evidence suggesting that the CAR and NPL variables do not have a significant impact on ROA. Several LDR and NIM variables significantly influence ROA.

Keywords: Capital Adequacy Ratio (CAR), Loan to Deposit Ratio (LDR), Net Interest Margin (NIM), Non-Performing Loan (NPL), Return On Asset (ROA).

Abstrak
Tujuan dari penelitian ini adalah untuk mengetahui pengaruh tingkat kesehatan bank terhadap return on asset (ROA) pada bank pemerintah dan swasta periode triwulan 2016-2022. Dalam penelitian ini menggunakan metode penelitian kuantitatif dengan menggunakan data sekunder yang diperoleh melalui situs resmi OJK (Otoritas Jasa Keuangan). Alat analisis yang digunakan dalam penelitian ini adalah analisis regresi data panel menggunakan E-Views 9. Berdasarkan hasil penelitian pada bank pemerintah, secara parsial variabel CAR dan LDR tidak berpengaruh signifikan terhadap ROA. Namun variabel NPL dan NIM berpengaruh secara signifikan terhadap ROA. Di sisi lain, bank swasta menunjukkan bahwa variabel CAR dan NPL tidak berpengaruh signifikan terhadap ROA. Sedangkan variabel LDR dan NIM berpengaruh secara signifikan terhadap ROA.

Kata kunci: Capital Adequacy Ratio (CAR), Loan to Deposit Ratio (LDR), Net Interest Margin (NIM), Non-Performing Loan (NPL), Return On Asset (ROA).
Konsep Perilaku Keputusan Pembelian Game Online
Authors: Asnawi Aisah , Tehuayo Erlinda , Marsulam Abdul Hafid 
Published: June 2023

E-Sport sports have been recognized as sports since 2020. The rise of technological developments makes game applications more very diverse and competitive. Data shows that the number of online game players increases every year. The increase in players is an opportunity for manufacturers to offer increasingly challenging game applications and various features in games that are economically profitable. This study aims to determine the effect of online promotions conducted by the company, the involvement of reference groups, and the comfort of game applications made on the purchasing decision of the online game application. This study uses a quantitative method, Partial Least Square (PLS). The sample was purposive sampling, with many respondents of as many as 30 game players. The results showed that game manufacturers' online promotions largely determine gamers' purchasing decisions. However the most decisive factor is the reference group for gamers in purchasing a game application. While the ease of the application also determines the number of consumers who download the application.

Keywords: Reference Group, Ease Of Application, Purchasing Decisions, Online Promotions

Abstrak
Olahraga e-sport diakui sebagai cabang olahraga sejak tahun 2020. Maraknya perkembangan tekhnologi membuat aplikasi game menjadi lebih sangat beragam dan kompetitif. Data menunjukkan bahwa jumlah pemain game online meningkat setiap tahun. Hal ini merupakan kesempatan bagi produsen untuk menawarkan aplikasi game yang semakin menantang dan berbagai fitur pada game yang menguntungkan secara ekonomi. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh promosi online yang dilakukan oleh perusahaan, keterlibatan kelompok referensi dan kenyamanan aplikasi game yang dibuat terhadap keputusan pembelian aplikasi game online tersebut. Penelitian ini menggunakan metode kuantitatif yaitu Partial Least Square (PLS). Sampel yang digunakan adalah purposive sampling dengan jumlah responden sebanyak 30 orang pemain game. Hasil penelitian menunjukkan bahwa promosi secara online yang digunakan oleh produsen game sangat menentukan keputusan pembelian dikalangan gamer. Namun faktor yang paling menentukan adalah kelompok referensi yang menjadi acuan bagi gamer dalam pembelian sebuah aplikasi game. Sedangkan kemudahan aplikasi juga ikut menentukan banyaknya konsumen yang mendownload aplikasi tersebut.

Kata Kunci: Kelompok Referensi, Kemudahan Aplikasi, Keputusan Pembelian, Promosi Online
Pemanfaatan Limbah Plastik Menjadi Modul Pembentuk Dinding Terawang Dari Limbah Plastik
Authors: Leksono Erick Teguh , Dewanto Rully Ario , Fadhlan Muhammad 
Published: June 2023

Pemanfaatan Limbah Plastik Menjadi Modul Pembentuk Dinding Terawang / Roster Pada Bangunan yang Bernilai Jual Tinggi di Desa Ciangsana, Gunung Puteri, Bogor, Jawa Barat merupakan program Pengabdian kepada Masyarakat (PkM) untuk meningkatkan manajemen pengolahan limbah plastik yang meliputi pelatihan dan pendampingan proses Potensi Limbah Plastik pengolahan limbah plastik menjadi aneka modul dinding trawang/roster, pengelolaan keuangan, permodalan, metode pengemasan, teknik penjualan dan manajemen pemasaran serta kewirausahaan bagi para pengolah limbah plastik Permasalahannya tidak dapat mengolah limbah plastik menjadi produk bernilai tambah yang tinggi. Inovasi pengolahan limbah plastik berupa pengolahan limbah plastik menjadi aneka modul dinding trawang/roster yang menggabungkan beberapa fungsi desain produk yang estetik dan komprehensif. Solusinya melakukan strategi penumbuhan kelompok usaha baru pengolahan limbah pastik, melalui proses pelatihan, manajemen usaha, pemasaran, pendampingan lanjutan. Kontribusi mendasar khalayak sasaran adalah meningkatnya nilai tambah limbah plastik untuk menjadi produk bernilai jual tinggi yang dikelola oleh UMKM CINTA berbasis kelompok masyarakat. Rencana luaran berupa jasa, sistem, produk/barang, atau luaran lainnya yang ditargetkan berupa : produk aneka modul dinding trawang/roster dari limbah plastik, dan UMKM berbasis kelompok masyarakat. Pelatihan dan pendampingan dalam program ini meliputi : Pelatihan pertama Penyuluhan dan Praktek Pengolahan limbah pastik, Pelatihan kedua Penyuluhan dan Praktek Pengemasan, Pelatihan ketiga Penyuluhan dan Praktek Permodalan serta Keuangan, Pelatihan keempat Penyuluhan dan Praktek Penjualan serta Pemasaran online serta offline, Program PKM ini berlangsung dari tgl 26 November – 20 Desember 2022. Akhirnya diharapkan setelah pelatihan di atas muncul banyak wirausaha yang menggerakkan potensi ekonomi local berbasis limbah plastik.
Developing Smart City 5.0 Framework To Produce Competency
Authors: Gamayanto Indra , Nurhindarto Aris 
Published: June 2023

Abstract - Smart cities are essential things that must be applied in the face of globalization and competition. In smart city 5.0, three important things discussed are human resource development, smart marketing, and information technology. These three things cannot be separated from each other because they are related. Furthermore, the smart city 5.0 article is a development from the previous article, namely smart city 1.0-3.0. Smart City 5.0 provides four important formulas for developing a smart city and a framework to guide its implementation. The four formulas and the resulting framework will develop in the next article, namely intelligent intelligence. It will continue to make prototypes and smart city intelligence applications. The result of this article is a framework that is a concept and strategy in developing a smart region that is part of a smart city. This article is still under development and research will continue. Furthermore, the development of this research will certainly require several more stages in reaching the top of the research, namely a big picture of a smart city and performance measurement for each process contained in a smart city. Therefore, it takes the right steps and formulas to produce a smart city 5.0 framework Keywords - Smart city, Human resource, Marketing, Technology, Innovation
Cross-sectional investigation of mycological diagnosis challenges in Saudi Arabia
Authors: Khateb Aiah Mustafa , Alkhaibari Shatha Ali 
Published: June 2023

BackgroundThe global incidence of fungal infection has increased dramatically over the last two decades. Fungal diseases threaten both immunocompetent, and immunocompromised patients. The current fungal diagnostics status in Saudi Arabia needs to be evaluated, especially with the increase of the immunosuppressed population. This cross-sectional study investigated the gaps in mycological diagnosis on a national level.Materials and methodsThe call interview questionnaire responses were collected to evaluate the demand for fungal assays, diagnostic methods’ quality, and mycological expertise of laboratory technologists in both public and private medical intuitions. The data were analyzed using (IBM SPSS ® software version 22.0).ResultsA total of 57 hospitals from all Saudi regions participated in the questionnaire; however, only 32% received or processed mycological samples. Most participants were from the Mecca region (25%), Riyadh region (19%), and Eastern region (14%). The top fungal isolates identified were Candida spp., Aspergillus spp., and dermatophyte. Fungal investigation is highly requested by intensive care, dermatology, and obstetrics and gynecology units. Most laboratories rely on fungal culture and microscopic examination, which mostly identify Candida to the genus level, and use 37°C incubators for culture (67%). Antifungal susceptibility testing (AST) and serological and molecular methods are rarely performed and mostly outsourced. Using accurate identification and AST are the primary factors to improve fungal diagnosis in respect to turnaround time and cost. The three major obstacles identified were availability of facility (47%), reagents and kits (32%), and good training (21%).ConclusionsThe results indicated that fungal diagnosis demand was relatively higher in high-population regions. This study highlighted the gaps in fungal diagnostics reference laboratories to encourage their improvement in Saudi hospitals.
Impact of plaque and luminal morphology in balloon angioplasty of the femoropopliteal artery: an intravascular ultrasound analysis
Authors: Zou Yuchi , Tong Qiang , Wang Xuehu , Jiang Chuli , Dai Yuanbin , Zhao Yu , Cheng Jun 
Published: June 2023

ObjectiveTo assess the effect of plaque and luminal morphologies in balloon angioplasty of femoropopliteal lesions using intravascular ultrasound (IVUS).MethodsThis retrospective, observational study analyzed 836 cross-sectional images using IVUS, from 35 femoropopliteal arteries of patients who underwent endovascular treatment between September 2020 and February 2022. Pre- and post-balloon angioplasty images were matched per 5 mm. Post-balloon angioplasty images were grouped into successful (n = 345) and unsuccessful (n = 491) groups. Plaque and luminal morphologies (such as severity of calcification, vascular remodeling, and plaque eccentricity) were extracted before the balloon angioplasty procedure to identify the predictors of unsuccessful balloon angioplasty. Additionally, 103 images with severe dissection were analyzed using IVUS and angiography.ResultsIn univariate analyses, the predictive factors for unsuccessful balloon angioplasty were vascular remodeling (p &lt; .001), plaque burden (p &lt; .001), lumen eccentricity (p &lt; .001), and balloon/vessel ratio (p = .01). Predictive factors for severe dissections were the guidewire route (p &lt; .001) and balloon/vessel ratio (p = .04). In multivariate analysis, the predictive factors for unsuccessful balloon angioplasty included lumen eccentricity (odds ratio [OR]: 3.99, 95% confidence interval [CI]: 1.28–12.68, p = .02) and plaque burden (OR: 1.03, 95% CI: 1.02–1.04; p &lt; .001). For severe dissections, the independent risk factor was an eccentric guidewire route (OR: 2.10, 95% CI: 1.22–3.65, p = .01).ConclusionHigh plaque burden and luminal eccentricity were risk factors for failed femoropopliteal artery balloon angioplasty. Additionally, eccentric guidewire routes predicted severe dissection.
Transport of nitrite from large arteries modulates regional blood flow during stress and exercise
Authors: Muskat J. C. , Babbs C. F. , Goergen C. J. , Rayz V. L. 
Published: June 2023

BackgroundAcute cardiovascular stress increases systemic wall shear stress (WSS)–a frictional force exerted by the flow of blood on vessel walls–which raises plasma nitrite concentration due to enhanced endothelial nitric oxide synthase (eNOS) activity. Upstream eNOS inhibition modulates distal perfusion, and autonomic stress increases both the consumption and vasodilatory effects of endogenous nitrite. Plasma nitrite maintains vascular homeostasis during exercise and disruption of nitrite bioavailability can lead to intermittent claudication.HypothesisDuring acute cardiovascular stress or strenuous exercise, we hypothesize enhanced production of nitric oxide (NO) by vascular endothelial cells raises nitrite concentrations in near-wall layers of flowing blood, resulting in cumulative NO concentrations in downstream arterioles sufficient for vasodilation.Confirmation and implicationsUtilizing a multiscale model of nitrite transport in bifurcating arteries, we tested the hypothesis for femoral artery flow under resting and exercised states of cardiovascular stress. Results indicate intravascular transport of nitrite from upstream endothelium could result in vasodilator-active levels of nitrite in downstream resistance vessels. The hypothesis could be confirmed utilizing artery-on-a-chip technology to measure NO production rates directly and help validate numerical model predictions. Further characterization of this mechanism may improve our understanding of symptomatic peripheral artery occlusive disease and exercise physiology.
Predictive value of CHA2DS2-VASc score in radial artery occlusion after transradial coronary angiography
Authors: Nadir Aydın , AY Nuray Kahraman 
Published: June 2023

BackgroundRadial artery occlusion is the most common complication of transradial catheterization. RAO is characterized by thrombus formation due to catheterization and endothelial damage. CHA2DS2-VASc scores are the current scoring systems used to determine the risk of thromboembolism in patients with atrial fibrillation. The aim of this study was to investigate the relationship of CHA2DS2-VASc score with radial artery occlusion.MethodsThis prospectively designed study was included 500 consecutive patients who underwent coronary artery transradial catheterization for diagnostic or interventional procedures. The diagnosis of radial artery occlusion was made by palpation examination and Doppler ultrasound at the twenty-fourth hour after the procedure. Independent predictors of radial artery occlusion were determined by logistic regression analysis.ResultsRadial artery occlusion was observed at a rate of 9%. The CHA2DS2-VASc score was higher in the group of the patients who developed radial artery occlusion (p &lt; 0.001). Arterial spasm (OR: 2.76, 95% CI 1.18–6.45, p: 0.01), catheterization time (OR: 1.03, 95% CI 1.005–1.057, p: 0.01) and CHA2DS2-VASc score ≥ 3 (OR: 1.44, 95% CI 1.17–1.78, p: 0.00) as significant independent predictors of radial artery occlusion. A high CHA2DS2-VASc score was associated with the continuity of the occlusion after the treatment (OR:1.37, 95% CI 1.01–1.85, p: 0.03).ConclusionsAn easily applicable CHA2DS2-VASc score of ≥3 has a predictive value for radial artery occlusion.
De novo heterozygous pathogenic FBN1 variant in an autopsy case of multiple aneurysms and right renal artery dissection: a case report
Authors: MacGowan Taylor , McClinchey Taylor , Parcha Vibhu , Vatta Matteo , Litovsky Silvio , Arora Pankaj , Benson Paul V. 
Published: June 2023

BackgroundMarfan syndrome is a potentially fatal inherited autosomal dominant condition impacting the cardiovascular and the skeletal system with an estimated 25% cases caused by sporadic genetic variations. Given the genetic inheritance pattern, an autopsy of probands with Marfan syndrome–associated mortality is critical to establish the phenotypic expression and clinical implications of the particular genetic variant, especially for first-degree relatives. We present the findings of a Marfan syndrome proband decedent presenting with sudden onset abdominal pain and unexplained retroperitoneal abdominal hemorrhage.MethodsAn autopsy was performed to inform the blood relatives of the phenotypic expression and penetrance of the potentially heritable condition. A clinical laboratory improvement amendment (CLIA)-certified clinical grade genetic sequencing was performed to identify pathogenic variants in genes associated with aortopathy.ResultsThe autopsy showed intra-abdominal and retroperitoneal hemorrhage due to infarction of the right kidney caused by dissection of the right renal artery. Genetic testing identified a heterozygous pathogenic FBN1 gene variant. The specific variant is FBN1 NM_000138.4 c.2953G &gt; A p.(Gly985Arg).ConclusionsWe report a case of a previously undiagnosed Marfan syndrome death due to a de novo FBN1 variant, c.2953G &gt; A.
Carotid geometry is independently associated with complicated carotid artery plaques
Authors: Strecker Christoph , Kopczak Anna , Saam Tobias , Sepp Dominik , Hennemuth Anja , Mayerhofer Ernst , Poli Sven , Ziemann Ulf , Poppert Holger , Schindler Andreas , Harloff Andreas 
Published: June 2023

IntroductionComplicated carotid artery plaques (cCAPs) are associated with an increased risk of rupture and subsequent stroke. The geometry of the carotid bifurcation determines the distribution of local hemodynamics and could thus contribute to the development and composition of these plaques. Therefore, we studied the role of carotid bifurcation geometry in the presence of cCAPs.MethodsWe investigated the association of individual vessel geometry with carotid artery plaque types in the Carotid Plaque Imaging in Acute Stroke (CAPIAS) study. After excluding arteries without plaque or with insufficient MRI quality, 354 carotid arteries from 182 patients were analyzed. Individual parameters of carotid geometry [i.e., internal carotid artery (ICA)/common carotid artery (CCA) ratio, bifurcation angle, and tortuosity) were derived from time-of-flight MR images. The lesion types of carotid artery plaques were determined according to the American Heart Association classification of lesions by multi-contrast 3T-MRI. The association between carotid geometry and a cCAP was studied using logistic regression after adjusting for age, sex, wall area, and cardiovascular risk factors.ResultsLow ICA/CCA ratios (OR per SD increase 0.60 [95%CI: 0.42–0.85]; p = 0.004) and low bifurcation angles (OR 0.61 [95%CI: 0.42–0.90]; p = 0.012) were significantly associated with the presence of cCAPs after adjusting for age, sex, cardiovascular risk factors, and wall area. Tortuosity had no significant association with cCAPs. Only ICA/CCA ratio remained significant in a model containing all three geometric parameters (OR per SD increase 0.65 [95%CI: 0.45–0.94]; p = 0.023).ConclusionsA steep tapering of the ICA relative to the CCA and, to a lesser extent, a low angle of the carotid bifurcation were associated with the presence of cCAPs. Our findings highlight the contribution of bifurcation geometry to plaque vulnerability. Thus, assessment of carotid geometry could be helpful in identifying patients at risk of cCAPs.
Risk prediction in patients with classical low-flow, low-gradient aortic stenosis undergoing surgical intervention
Authors: Tessari Fernanda Castiglioni , Lopes Maria Antonieta Albanez A. de M. , Campos Carlos M. , Rosa Vitor Emer Egypto , Sampaio Roney Orismar , Soares Frederico José Mendes Mendonça , Lopes Rener Romulo Souza , Nazzetta Daniella Cian , de Brito Jr Fábio Sândoli , Ribeiro Henrique Barbosa , Vieira Marcelo L. C. , Mathias Wilson , Fernandes Joao Ricardo Cordeiro , Lopes Mariana Pezzute , Rochitte Carlos E. , Pomerantzeff Pablo M. A. , Abizaid Alexandre , Tarasoutchi Flavio 
Published: June 2023

IntroductionClassical low-flow, low-gradient aortic stenosis (LFLG-AS) is an advanced stage of aortic stenosis, which has a poor prognosis with medical treatment and a high operative mortality after surgical aortic valve replacement (SAVR). There is currently a paucity of information regarding the current prognosis of classical LFLG-AS patients undergoing SAVR and the lack of a reliable risk assessment tool for this particular subset of AS patients. The present study aims to assess mortality predictors in a population of classical LFLG-AS patients undergoing SAVR.MethodsThis is a prospective study including 41 consecutive classical LFLG-AS patients (aortic valve area ≤1.0 cm2, mean transaortic gradient &lt;40 mmHg, left ventricular ejection fraction &lt;50%). All patients underwent dobutamine stress echocardiography (DSE), 3D echocardiography, and T1 mapping cardiac magnetic resonance (CMR). Patients with pseudo-severe aortic stenosis were excluded. Patients were divided into groups according to the median value of the mean transaortic gradient (≤25 and &gt;25 mmHg). All-cause, intraprocedural, 30-day, and 1-year mortality rates were evaluated.ResultsAll of the patients had degenerative aortic stenosis, with a median age of 66 (60–73) years; most of the patients were men (83%). The median EuroSCORE II was 2.19% (1.5%–4.78%), and the median STS was 2.19% (1.6%–3.99%). On DSE, 73.2% had flow reserve (FR), i.e., an increase in stroke volume ≥20% during DSE, with no significant differences between groups. On CMR, late gadolinium enhancement mass was lower in the group with mean transaortic gradient &gt;25 mmHg [2.0 (0.0–8.9) g vs. 8.5 (2.3–15.0) g; p = 0.034), and myocardium extracellular volume (ECV) and indexed ECV were similar between groups. The 30-day and 1-year mortality rates were 14.6% and 43.8%, respectively. The median follow-up was 4.1 (0.3–5.1) years. By multivariate analysis adjusted for FR, only the mean transaortic gradient was an independent predictor of mortality (hazard ratio: 0.923, 95% confidence interval: 0.864–0.986, p = 0.019). A mean transaortic gradient ≤25 mmHg was associated with higher all-cause mortality rates (log-rank p = 0.038), while there was no difference in mortality regarding FR status (log-rank p = 0.114).ConclusionsIn patients with classical LFLG-AS undergoing SAVR, the mean transaortic gradient was the only independent mortality predictor in patients with LFLG-AS, especially if ≤25 mmHg. The absence of left ventricular FR had no prognostic impact on long-term outcomes.