bluuebunny/crossref_metadata_2025_split huggingface dataset:
Changes in Nursing Home Use Following Medicaid-Supported Expanded Access to Home- and Community-Based Services for Older Adults With Dementia
Authors: Harrison Jordan M. , Sheng Flora , Josberger Raina E. , Liu Harry H. , Stone Patricia W. , Luchsinger José A. , Dick Andrew W. 
Published: July 2023

ImportanceNew York State’s Medicaid managed long-term care (MLTC) program expanded access to home- and community-based services, providing an alternative to nursing home care for people with dementia. Between 2012 and 2015, the state implemented mandatory MLTC for dual Medicare and Medicaid enrollees requiring more than 120 days of community-based long-term care.ObjectiveTo evaluate changes in nursing home use among older adults with dementia following MLTC implementation.Design, Setting, and ParticipantsThis cohort study used longitudinal data from January 1, 2011, to December 31, 2019, from the Minimum Data Set and Medicare administrative data. The study sample included New York State Medicare beneficiaries 65 years and older with dementia. New York City residents were excluded due to insufficient pre–study period data. Data were analyzed from January 1, 2011, to December 31, 2019.ExposureMandatory MLTC enrollment.Main Outcomes and MeasuresLongitudinal models were used to evaluate changes in annual days of nursing home use following the staggered implementation of MLTC across 13 regions of the state. Two models were estimated: (1) a logistic regression model for any nursing home use in a given year and (2) a linear regression model of total nursing home days, conditional on any nursing home use. Models included annual event-time indicators specified as years until or since MLTC implementation. To capture MLTC effects for dual enrollees relative to non–dual Medicare enrollees, models included interaction terms for dual enrollment and event-time indicators.ResultsThis sample included 463 947 Medicare beneficiaries with dementia who lived in New York State between 2011 and 2019 (50.2% younger than 85 years; 64.4% women). Implementation of MLTC was associated with lower odds of nursing home use among dual enrollees, ranging from 8% lower odds 2 years post implementation (adjusted odds ratio, 0.92 [95% CI, 0.86-0.98]) to 24% lower odds 6 years post implementation (adjusted odds ratio, 0.76 [95% CI, 0.69-0.84]). Compared with a scenario of no MLTC, MLTC implementation was associated with an 8% reduction in annual days of nursing home use between 2013 and 2019 (mean, −5.6 [95% CI, −6.1 to −5.1] days per year).Conclusions and RelevanceThe findings of this cohort study suggest that implementation of mandatory MLTC in New York State was associated with less nursing home use among dual enrollees with dementia and that MLTC may help prevent or delay nursing home placement among older adults with dementia.
Undifferentially Expressed CXXC5 as a Transcriptionally Regulatory Biomarker of Breast Cancer
Authors: Li Xue , Lv Xiaoying , Li Haijun , Zhang Gongyou , Long Yaohang , Li Kewei , Fan Yusi , Jin Dawei , Zhou Fengfeng , Liu Hongmei 
Published: July 2023

AbstractThis work hypothesizes that some genes undergo radically changed transcription regulations (TRs) in breast cancer (BC), but don't show differential expressions for unknown reasons. The TR of a gene is quantitatively formulated by a regression model between the expression of this gene and multiple transcription factors (TFs). The difference between the predicted and real expression levels of a gene in a query sample is defined as the mqTrans value of this gene, which quantitatively reflects its regulatory changes. This work systematically screens the undifferentially expressed genes with differentially expressed mqTrans values in 1036 samples across five datasets and three ethnic groups. This study calls the 25 genes satisfying the above hypothesis in at least four datasets as dark biomarkers, and the strong dark biomarker gene CXXC5 (CXXC Finger Protein 5) is even supported by all the five independent BC datasets. Although CXXC5 does not show differential expressions in BC, its transcription regulations show quantitative associations with BCs in diversified cohorts. The overlapping long noncoding RNAs (lncRNAs) may have contributed their transcripts to the expression miscalculations of dark biomarkers. The mqTrans analysis serves as a complementary view of the transcriptome‐based detections of biomarkers that are ignored by many existing studies.
Elimination of Drying‐Dependent Component Deviation Using a Composite Solvent Strategy Enables High‐Performance Inkjet‐Printed Organic Solar Cells with Efficiency Approaching 16%
Authors: Sang Lifeng , Chen Xingze , Fang Jin , Xu Peng , Tian Wenming , Shui Ke , Han Yunfei , Wang Hao , Huang Rong , Zhang Qing , Luo Qun , Ma Chang‐Qi 
Published: July 2023

AbstractInkjet printing (IJP) is a roll‐to‐roll (R2R) compatible fabrication method for large‐area organic solar cells (OSCs). Unlike the coating process, the films are formed through droplet leveling and merging during IJP, and the pre‐deposited droplets are partly dissolved by the subsequent droplets. Such a process yields undesired printing pattern lines, especially in large‐area printed films. This study reveals that such a temperature‐dependent “drying lines‐related” phase separation morphology has caused component variation in the organic blend films, which leads to an obvious inhomogeneity of photocurrent in the printed OSCs. Such a phenomenon is attributed to the solubility difference between organic donor and acceptor molecules in the main printing solvent. A composite solvent strategy of ortho‐dichlorobenzene (oDCB)/trimethylbenzene (TMB) and tetralin (THN) is developed to solve this problem. The introduction of THN suppresses the formation of printing drying lines during high‐temperature printing due to the preferential miscibility of acceptor in THN, leading to the efficiency improvement to 13.96% and 15.78% for the binary and ternary devices. In addition, the 1 cm2 device with a disruptive pattern gives an efficiency of 12.80% and a certificated efficiency of 12.18%.
Synthesis of epoxy and phenyl groups‐containing polyhedral oligomeric silsesquioxane of large Si16O24 cage and its flame retardant and mechanical performances on epoxy resins
Authors: Zhou Hailian , Liu Leichun , Zhang Wenchao , Yang Rongjie 
Published: July 2023

AbstractA kind of the epoxy and phenyl groups‐containing POSS of the regular cage of 16 silicon atoms (EPHPOSS) was synthesized successfully via the hydrolysis‐condensation reaction of phenyltrimethoxysilane and 2‐(3,4‐glycidoxypropyl) propyltrimethoxysilane, and its chemical structure was characterized. To improve the comprehensive performances of the epoxy resin (EP), EPHPOSS in different ratios was incorporated into the EP by thermal curing technology. It is obtained that the EPHPOSS has a homogeneous dispersion in the EP composites and plays an important role in enhancing the bending strength and thermal properties of the EP composites. The EP composite with 10 wt% EPHPOSS has a limiting oxygen index (LOI) value of 27.8%, higher than the LOI of 23.2% of the pure EP. The peak of heat release rate, total heat release, and total smoke release of the EP composites with the EPHPOSS are reduced obviously. In flame retardant mechanism of the EPHPOSS on the EP, the microstructures of the burning char and TG‐FTIR of the EP composites were achieved, it is suggested that the EPHPOSS promotes the formation of compact and continuous char layers and reduces the production of the organic combustible gases.
Effects of exogenous indole‐3‐acetic acid on the density of trichomes, expression of artemisinin biosynthetic genes, and artemisinin biosynthesis in Artemisia annua
Authors: Guo Zhiying , Zhang Qin , Zhang Yitong , Wu Changlin , Zheng Yijuan , Tong Fupeng , Zhang Linhui , Lu Ruyu , Pan Xiusong , Tan Hexin , Lv Zongyou 
Published: July 2023

AbstractArtemisinin is the most practical medication for the treatment of malaria, but is only very minimally synthesized in Artemisia annua, significantly less than the market needs. In this study, indole‐3‐acetic acid (IAA) was used to investigate its effects on trichomes, artemisinin accumulation, and biosynthetic gene expression in A. anuua. The results showed that exogenous IAA could contribute to the growth and development of A. annua and increase the density of trichomes. Analysis using liquid chromatography‐tandem mass spectrometry (LC‒MS/MS) indicated that artemisinin and dihydroartemisinic acid (DHAA) contents were increased by 1.9‐fold (1.1 mg/g) and 2.1‐fold (0.51 mg/g) after IAA treatment in comparison with control lines (CK), respectively. Furthermore, quantitative real‐time PCR results showed that AaADS, AaCYP71AV1, AaALDH1, and AaDBR2, four critical enzyme genes for the biosynthesis of artemisinin, had relatively high transcription levels in leaves of A. annua treated with IAA. In summary, this study indicated that exogenous IAA treatment was a feasible strategy to enhance artemisinin production, which paves the way for further metabolic engineering of artemisinin biosynthesis.
Activated omega loops for anterior crossbite correction in transitional dentition
Authors: Venugopal Adith , Ahmed Farooq , Yadav Rajiv , Bunthouen Noem 
Published: July 2023

Key Clinical MessageSeveral approaches can correct pseudo‐Class III anterior crossbite. 2 × 4 appliance, compressed open‐coil springs, Class III elastics, etc. All cause either soft tissue lacerations, smile line flattening, or upper incisor overproclination. This paper describes a novel method to tip lower incisors into a normal overjet without compromising the upper dentition.AbstractIn pseudo‐class III cases, a “two by four” multibracketed appliance has been utilized to put the incisors into a typical overjet during transitional dentition. Compressing a rectangular super elastic archwire creates continuous force, but its length restricts activation and risks cheek impingement. Open‐coil springs on rigid archwires advance incisors labially, although a 4‐5 mm of wire distal to the molar tube may injure soft tissue. Reciprocally anchored Class III intermaxillary elastics restore anterior overjet through lower incisor lingual tipping and upper incisor proclination. Class III elastics extrude maxillary molars and mandibular incisors, rotating the dental occlusal plane counterclockwise and reducing maxillary incisor exposure and aesthetics. A unique method is reported in this report to tip the lower incisors back into normal overjet without affecting the upper dentition.
Identification and taxonomic position of a new Pseudoomphalina species from Pakistan based on light, scanning electron microscopy, and molecular analysis
Authors: Rani Afifa Kainat , Hina Shozab , Iqbal Hira , Shabbir Zahra , Izhar Aiman , Usman Muhammad , Khalid Abdul Nasir 
Published: July 2023

AbstractKhanspur, a small town located near Ayubia National Park, is a famous mountainous resort lying in Galyat area of Khyber Pakhtunkhwa. It is included in one of the richest biodiversity hotspots in the country. Despite of extensive previous studies, many new species are awaiting to be documented, including macrofungi. In this study, a new macrofungus Pseudoomphalina khanspurensis is analyzed by both light and scanning electron microscopy as well as DNA sequences based on nrITS and nrLSU regions. The sister species P. cokeri differs by its red to purple, dark to reddish brown, broadly convex to applanate pileus, purple blue to brownish stipe, and numerous cylindrical to lageniform cheilocystidia.Highlights
This is the first report of genus Pseudoomphalina from Pakistan and first study based on Scanning electron microscopy.
These species have been described with detailed micro‐morphological and molecular makers (nrITS and nrLSU).
General distribution, ecology, diagnostic features and comparisons with alies have been provided.
Graphical representation of DNA extraction and geographical locations of sampling sites are also illustrated.
Softwares such as CIPRES Science Gateway Portal, MUSCLE, BioEdit, FigTree, Adobe illustrator and Adobe Photoshop are used in the current study.
No member of this genus is already described from Pakistan.
Characterization of graphs of diameter 2 containing a homeomorphically irreducible spanning tree
Authors: Shan Songling , Tsuchiya Shoichi 
Published: July 2023

AbstractA spanning tree of a graph with no vertex of degree 2 is called a homeomorphically irreducible spanning tree (HIST) of the graph. In 1990, Albertson, Berman, Hutchinson, and Thomassen conjectured that every twin‐free graph with diameter 2 contains a HIST. Recently, Ando disproved this conjecture and characterized twin‐free graphs with diameter 2 that do contain a HIST. In this paper, we give a complete characterization of all graphs of diameter 2 that contain a HIST. This characterization gives alternative proofs for several known results.
A Biomimetic Peptide Functions as Specific Extracellular Matrix for Quiescence of Stem Cells against Intervertebral Disc Degeneration
Authors: Li Yuan , Zhang Kuo , Ai Xuezheng , Zhang Qingshi , Jiang Lu , Long Jiang , Xu Huange , Feng Chencheng , Zhang Yaqing , Tang Guoke , Chong Fanli , Wang Lei , Huang Bo 
Published: July 2023

AbstractMaintaining quiescence of stem cells is a potential way to decrease cell nutrition demand for restoring the organization. Herein, a biomimetic peptide to maintain quiescence of stem cells through C‐X‐C motif chemokine ligand 8 (CXCL8)‐C‐X‐C motif chemokine receptor 1 (CXCR1) pathway against intervertebral disc degeneration (IVDD) is developed. First, it is confirmed that quiescence can be induced via inhibiting phosphatidylinositol 3‐kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway in nucleus pulposus stem cells (NPSCs). Meanwhile, it is well known that CXCR1, a chemokine receptor, can be targeted by CXCL8, resulting in cell proliferation via activating PI3K/Akt/mTOR pathway. Second, a biomimetic peptide (OAFF) that can bind to CXCR1 and form fibrous networks on NPSCs, mimicking extracellular matrix formation is developed. The multivalent effect and long‐term binding to CXCR1 on NPSCs of OAFF fibers offer forcefully competitive inhibition with natural CXCL8, which induces NPSCs quiescence and ultimately overcomes obstacle in intradiscal injection therapy. In rat caudal disc puncture model, OAFF nanofibers still maintain at 5 weeks after operation and inhibit degeneration process of intervertebral disc in terms of histopathology and imageology. In situ fibrillogenesis of biomimetic peptide on NPSCs provides promising stem cells for intradiscal injection therapy against IVDD.
Optimierte Fachbodenregale durch den Einsatz von höchstfestem Stahl
Authors: Ungermann Dieter , Lemański Tim , Brune Bettina , Weiß‐Borkowski Nathalie , Schulz‐Beenken Anne , Gösling Peter , Ebers Markus 
Published: July 2023

AbstractWeltweit wird die Lagertechnik durch den boomenden Onlinehandel, begrenzte Flächenkapazitäten und immer größere Bauhöhen von Regallagern geprägt. Die technische Ausführung von Regalanlagen folgt der rasanten Entwicklung in der Logistik jedoch nur schleppend. Auch das Potenzial von modernen höchstfesten Stählen, die sich im Automobil‐ und Maschinenbau längst durchgesetzt haben, wird in der modernen Lagertechnik nicht ausgeschöpft, obwohl Fachbodenregale für den Einsatz von höchstfesten Stählen prädestiniert sind. Das Ziel des FOSTA‐Forschungsvorhabens P1512 (IGF Nr.21465/N) war daher die Erarbeitung der werkstoffspezifischen, fertigungs‐ und bemessungstechnischen Grundlagen zum Einsatz von höchstfesten Stahlblechen in Fachbodenregalen. Hierzu wurde einerseits die Eignung verschiedener hochfester Stähle für ihren Einsatz bei Fachböden und Stützen geprüft. Andererseits wurde durch experimentelle Untersuchungen das Trag‐ und Stabilitätsverhalten von Fachbodenregalstützen aus hochfesten Stählen analysiert; numerische Simulationen dienten der Optimierung von Stützengeometrien, sodass deren Querschnitte bei geringstmöglichem Materialeinsatz bestmöglich ausgenutzt werden können.
Corporate entrepreneurship and firm performance relationship under the moderating effect of environmental dynamism: Replication and extension analysis
Authors: Rodríguez-Peña Antonio 
Published: July 2023

AbstractThe purpose of this research is to understand the relationship between corporate entrepreneurship and firm performance of large firms in emerging economies, with consideration of the moderating effect of environmental dynamism. This is a quantitative and cross-sectional study, utilizing a multivariate second-order hierarchical component model. The partial least squares structural equation modeling method was employed for analysis. The findings indicate a highly positive impact of entrepreneurial orientation on profitability, while corporate venturing had a high but negative impact on profitability. Regarding the growth model, it was shown that entrepreneurial orientation had a positive but statistically insignificant impact on firm growth, while corporate venturing had a highly negative but statistically insignificant impact on firm growth. Interestingly, the results indicate that environmental dynamism did not have a moderating effect in this context. This paper has significant implications for senior management decision-making regarding the importance of corporate entrepreneurship in the growth and profitability of companies. It is recommended that large companies invest in entrepreneurial orientation because of its positive influence on profitability. This research fills a gap in the literature on the relationship between corporate entrepreneurship and firm performance in large companies in emerging economies. It highlights the importance of context-specific contingencies to the impact of corporate entrepreneurship on the performance of large companies and cautions against generalizing results across different countries, even those with seemingly similar contexts. The study confirms the positive relationship between entrepreneurial orientation and corporate profitability, particularly for large companies.
$$\mathrm T^2$$Net: an improved image-based text transfer framework using background inpainting and text conversion
Authors: Zhou Haibin , Shao Lujiao , Jia Boxiang , Zhang Haijun 
Published: July 2023

AbstractText, which is regarded as one of the important clues for visual recognition, can provide rich and accurate high-level semantic information. Therefore, the detection and recognition of textual data have become a research hotspot in computer vision and artificial intelligence. However, the difficulty of data collection and the non-uniform distribution of characters still poses challenges for accurate text recognition, especially for recognizing complicated character sets, such as Chinese. To address small-sample text recognition, we propose an improved image-based text transfer framework, named $$\mathrm T^2$$

T
2

Net. This work can replace or modify the text content in an image so as to arbitrarily expand a recognition data set. Considering that the main challenge of text transfer lies in decoupling the complex interrelationship between text and background, a text content mask branch is first added into a background inpainting module so as to more realistically restore background textures. Second, a text recognition model is developed to guide the readability of the text transfer results in the text conversion module. Finally, a text fusion module is used to fuse the independent migrations of background and text. We examined the performance of our proposed framework in a real-word scene text recognition data set. Qualitative and quantitative results have proved the efficiency of our method in comparison with previous works.
Making Love Legible: Queering Indian Legal Conceptions of “Family”
Authors: Jain Hrishika 
Published: July 2023

AbstractThe state has historically played favourites—by incentivizing conventional families and clamping down on alternative families like ascetic maths, it ensured that the heteronormative family flourished. I trace the socio-legal histories of families and establish a constitutional imperative for “family equality” located in the rights to religious freedom, privacy, and equal treatment, and propose that it (not marriage equality) drives the queer movement. “Family” must be reimagined beyond marriage in light of the public ethic of care to encompass a vast range of non-normative families like hijra communes. I consider the Canadian Law Commission’s proposals for recognizing “families” and argue that a similar framework is an unrecognized constitutional mandate in India that, once recognized, would render a wealth of laws interacting with family life unconstitutional. The shared socioconstitutional contexts across jurisdictions and the growing convergence of human rights standards could well mean that this will impact legal systems around the world.
A new species of Ophiocoma (Echinodermata: Ophiuroidea) from Archipelago Trindade and Martin Vaz, Southeastern Atlantic, and redescription of Ophiocoma echinata
Authors: Serrano Helena , Damiano Cecília J. S. , Alitto Renata A. S. , Guilherme Pablo D. B. , Cerqueira Walter R. P. , Mendonça Joel B. , Tavares Marcos , Borges Michela 
Published: July 2023

Abstract
The brittle stars of the family Ophiocomidae inhabit shallow waters and coral reefs of tropical regions. The species of Ophiocoma are difficult to identify due to high morphological variation, especially when different stages of development are observed. Here, based on morphological analyses, two Brazilian morphotypes of Ophiocoma were studied and characterized, Ophiocoma sp. NB (Northeastern Brazil) and Ophiocoma sp. TMV (Trindade and Martin Vaz Archipelago), and subsequently thoroughly analysed to confirm whether they were the same species or not. After the morphological studies, including external morphology, morphometry and microstructural characters, and analysis of molecular data, involving the 16S gene, it was concluded that Ophiocoma sp. NB and Ophiocoma sp. TMV do not correspond to the same species, the first being identified as Ophiocoma echinata (Lamarck, 1816) and the latter being a new species. This new species is characterized by two tentacle scales on the first arm segment and then one on all following segments, and the dorsalmost arm spines are robust and rounded, as wide as long or almost as wide as long.
Invasive listeriosis in Finland: surveillance and cluster investigations, 2011–2021
Authors: Suominen Kristiina , Jaakola Sari , Salmenlinna Saara , Simola Maria , Wallgren Suvi , Hakkinen Marjaana , Suokorpi Annika , Rimhanen-Finne Ruska 
Published: July 2023

Abstract
Foodborne pathogen Listeria monocytogenes may cause serious, life-threatening disease in susceptible persons. We combined data from Finnish national listeriosis surveillance, patient interview responses, and laboratory data of patient samples and compared them to listeria findings from food and food production plants collected as part of outbreak investigations during 2011–2021. The incidence of invasive listeriosis in Finland (1.3/100000 in 2021) is higher than the EU average (0.5/100000 in 2021), and most cases are observed in the elderly with a predisposing condition. Many cases reported consuming high-risk foods as well as improper food storage. Since ongoing patient interviews and whole genome sequencing were introduced, several listeriosis outbreaks were detected and food sources identified. Recommendations about high-risk foods for listeriosis and proper food storage should be better communicated to susceptible people. In Finland, patient interviews and typing and comparing listeria isolates in foods and patient samples are crucial in solving outbreaks and determining measures to control invasive listeriosis.