bluuebunny/crossref_metadata_2025_split huggingface dataset:
Overcapacity of Chinese Industrial Enterprises’ Measurement and Governance
Authors: Yang Y , Gu R , Liu YF 
Published: January 2023

Abstract
Accurately measuring the capacity utilization of enterprises is a prerequisite for evaluating China's excess capacity of governance performance. This paper uses three-stage DEA to measure the capacity utilization of Chinese main industrial enterprises from 1998 to 2019excluding the influence of traditional DEA methods ignoring the environmental differences and random factors on the measurement results. And empirically evaluates the policy performance of administrative overcapacity governance. The results show that the overall capacity utilization of Chinese industrial enterprises is relatively low, and on average, industrial enterprises above the state designated scale are lower than listed enterprises. The governance policies have a very significant inhibitory effect on overcapacity with obvious industry and regional heterogeneity. Meanwhile, only enterprises with overcapacity are sensitive to control policies, showing precise control goals and good governance performance. Therefore, apart from adjusting the institutional distortions stimulating overcapacity in the long term, maintaining the density and intensity of administrative governance policies in the short term is equally important for overcapacity governance.
JEL Classification L50·O11·R11
The influence of additives on the thermal and mechanical behavior of Labu Sayong from Perak, Malaysia
Authors: Metselaar Hendrik Simon Cornelis , Muhammad Ros Fatihah , Taib Nur Iskandar , Thana’Ani Nur Amalina Ahmad , Nazri Siti Nadzirah , Akhiani Amir Reza , Zamari Mohd Pareb 
Published: January 2023

Abstract
The authors have requested that this preprint be removed from Research Square.
Associations between endometriosis and adverse pregnancy and perinatal outcomes: a population-based cohort study
Authors: Gebremedhin Amanuel Tesfay , Mitter Vera R , Duko Bereket , Tessema Gizachew A , Pereira Gavin F 
Published: January 2023

Abstract
Purpose
To examine the association between endometriosis and adverse pregnancy and perinatal outcomes (preeclampsia, placenta previa, and preterm birth).
Methods
A population-based retrospective cohort study was conducted among 468,778 eligible women who contributed 912,747 singleton livebirths between 1980 and 2015 in Western Australia (WA). We used probabilistically linked perinatal and hospital separation data from the WA data linkage system’s Midwives Notification System and Hospital Morbidity Data Collection databases. We used a doubly robust estimator by combining the inverse probability weighting with the outcome regression model to estimate adjusted risk ratios (RR) and 95% confidence intervals (CIs).
Results
There were 19,476 singleton livebirths among 8,874 women diagnosed with endometriosis. Using a doubly robust estimator, we found pregnancies in women with endometriosis to be associated with an increased risk of preeclampsia with RR of 1.18, 95% CI 1.11–1.26, placenta previa (RR, 1.59, 95% CI 1.42–1.79) and preterm birth (RR 1.45, 95% CI 1.37–1.54). The observed association persisted after stratified by the use of Medically Assisted Reproduction, with a slightly elevated risk among pregnancies conceived spontaneously.
Conclusions
In this large population-based cohort, endometriosis is associated with an increased risk of preeclampsia, placenta previa, and preterm birth, independent of the use of Medically Assisted Reproduction. This may help to enhance future obstetric care among this population.
Identification of NTCP in human podocytes and its mediating effect on the direct HBV infection of kidney tissue
Authors: Lifen Wang , Cheng Wang , Xu Wang , Yantao Cao , Xiaohua Guo , Zhiming Ye 
Published: January 2023

Abstract
Background: Direct hepatitis B virus (HBV) infection in kidney tissue is associated with glomerulonephritis. However, it is unclear how HBV enters into kidney cells, We investigated the expression of sodium taurocholate cotransporting polypeptide (NTCP), an entry-specific receptor of HBV, in human renal podocytes and explored the ability of NTCP to mediate HBV-infected podocytes.
Methods: We detected the expression of NTCP in the renal tissue of patients with HBV and in cultured human podocytes using immunocytochemical and immunofluorescence co-localization along with western blotting. Human podocytes cultured in vitro were infected with HBV-containing supernatant derived from HepG2.2.15 cells. HBsAg, HBeAg, HBV DNA, HBV CCC DNA, and HBcAg in the podocytes were detected by ELISA, RT-PCR, and immunofluorescence.
Results: NTCP was expressed in the kidney podocytes of patients and in human renal podocytes cultured in vivo. HBsAg, HBeAg, HBV DNA, HBV CCC DNA, and HBcAg were expressed in cultured human podocytes with HBV-containing supernatant. Knocking down NTCP with shRNA attenuated the HBV infection in the cultured podocytes with HBV-containing supernatant.Up-regulateing NTCP with WT-NTCP enhanced HBV infection in the cultured podocytes with HBV-containing supernatant.
Conclusions: NTCP is expressed in human renal podocytes, where it mediates HBV infection. The findings provide a theoretical bases and a potential target (NTCP) for preventing the direct infection of podocytes by HBV.
Gas-mediated trace element incorporation into rhyolite-hosted topaz: A synchrotron microbeam XAS study
Authors: Schaub D.R. , Northrup Paul , Nekvasil Hanna , Catalano Tristan , Tappero Ryan 
Published: January 2023

Abstract
Magmatic gas exsolving during late-stage cooling of shallow magmas has been considered an important facilitator of low-pressure alteration and metal transport. However, the chemical properties of such gas, particularly its metal transport mechanisms and capacity, remain elusive. Trace elements in minerals produced by gas-mediated surface reaction or precipitation from gas capture details of gas composition and reaction pathways. However, interpretation of mineral trace element contents is dependent on understanding crystallographic controls on gas/mineral partitioning. This work investigates the structural accommodation of As, Mn, Ga, Ge, Fe, and Ti in vapor-deposited topaz of vesicular topaz rhyolite from the Thomas Range, Utah, through single-crystal synchrotron microbeam X-ray techniques on picogram quantities of those trace elements. X-ray absorption near edge structure (XANES) data indicates that these elements are incorporated into topaz as As5+, Fe3+, Mn3+, Ti4+, Ga3+, and Ge4+. Extended X-ray absorption fine structure (EXAFS) analysis for these trace elements, compared to EXAFS of structural Al and Si, reveals that As5+ and Ge4+ are incorporated directly into the tetrahedral site of the topaz structure, with the octahedral site accommodating Mn3+, Fe3+, Ga3+, and Ti4+. For As5+ and Fe3+, the structural impact of substitution extends to at least second neighbors (other elements were only resolvable to first neighbors). Further interpretation of the EXAFS results suggests that the substitution of Ti4+ results in increased distortion of the octahedral site, while the other trace elements induce more uniform expansion correlating in magnitude to their ionic radius. Comparison of quantified X-ray fluorescence (XRF) data for two topaz crystals from this rhyolite reveals variable trace element concentrations for As5+, Fe3+, Ga3+, and Ti4+, reflective of a source gas undersaturated in these trace elements changing in concentration over the period of topaz deposition. The identical Ge4+ content of the two topaz crystals suggests that Ge4+ in the gas was buffered by the growth of another Ge4+-bearing phase, such as quartz. The very low Mn3+ content in the topaz crystals does not reflect the abundance of Mn3+ in the gas (saturation of Mn is evidenced by coexisting bixbyite). Instead, it suggests a strong Jahn-Teller inhibitory effect to the substitution of Mn3+ for Al3+ in the distorted octahedral site of topaz. It is proposed that exsolution of an HF-enriched gas from cooling rhyolitic magma led to local scouring of Al, Si, and trace metals from the magma. Once topaz crystals nucleated, self-catalyzed reactions that recycle HF led to continued growth of topaz.
Implementasi Pendidikan Karakter Islam di Masyarakat
Authors: Munawarah  , Hidayat Nur 
Published: January 2023

Tujuan penelilitian ini untuk menganalisis beberapa ayat al-Qur’an dan hadis yang berkaitan dengan pendidikan karakter Islam di masyarakat. Jenis penelitian ini adalah kajian pustaka (library research). Penelitian ini bersifat deskriptif analitis, yaitu dengan cara mengumpulkan data berupa beberapa ayat dan hadits yang berkaitan dengan pendidikan karakter Islam di masyarakat, kemudian menafsirkan data yang diperoleh, lalu mengadakan analisis dan interpretasi terhadap data tersebut. Adapun hasil penelitian ini menunjukkan bahwa pada beberapa ayat dan hadis tersebut terdapat nilai-nilai yang mendeskripsikan mengenai pendidikan karakter Islam di masyarakat, seperti halnya nilai relasi saling menghormati dalam Islam, gemar menolong orang lain, dan bersikap toleransi kepada orang lain.
Moda e Decolonialidade: Colonialismo, vestuário e binarismo
Authors: De Oliveira Santos Heloísa Helena , Medrado Mi 
Published: January 2023

Entendemos que o conceito Moda compõe, em seu espectro histórico-sociológico, categorias nascidas no seio da colonialidade do poder. A um só tempo, a noção de Moda associa capacidades intelectuais, produtivas, de cultura e espaço-tempo. Assim, perguntamos se há colonialismo nos primeiros textos sociológicos brasileiros que abordam a moda, notadamente em Gilberto Freyre e em Gilda de Mello e Souza. O objetivo deste trabalho é questionar como as diversas abordagens sobre o vestuário, desenvolvidas a partir da epistemologia do Eixo Norte, legitimam e produzem uma leitura que hierarquiza as relações de roupa, modos e moda, reproduzindo e divulgando a concepção de que o vestir das sociedades não-brancas está engessado ou é inferior. A proposta é problematizar o binarismo categórico da colonialidade Moda (desenvolvida) versus indumentária/traje (primitiva): este último relaciona os colonizados à ideia de tradição-cópia-indumentária, enquanto ao colonizador são associadas modernidade-inovação-moda. Nesta divisão, a moda europeia determina as categorias de classificação e relacionamento do vestuário no sistema-mundo, ao passo que, estabelece sua posição de hierarquia e poder no campo das decisões da moda, estabelecendo “A” forma de se relacionar e produzir. Desta maneira, como compreender as dinâmicas e as lacunas de silenciamentos e apagamentos que o projeto da modernidade impeliu como prática universal? Como formular uma crítica radical à epistemologia colonial que opõe criação versus cópia?
Contextos referenciais em narrativas da amazônia: uma análise de anáforas indiretas
Authors: Moura Heliud Luis Maia 
Published: January 2023

Este artigo objetiva analisar anáforas indiretas presentes em narrativas amazônicas, considerando que essas anáforas constroem processos referenciais i­­mersos no contexto em que tais narrativas são produzidas. As teorias que embasam este trabalho ancoram-se em Koch (2004; 2006; 2008); Marcuschi (2005; 2006; 2007); Schwartz (2000); Tesnière (1977); Tomasello (2003) e Moura (2013; 2017). As anáforas indiretas constituem atividades sociocognitivas e culturais, mobilizando-se processos como: anáforas indiretas (doravante AI) baseadas em relações semânticas inscritas nos SNs definidos e indefinidos; AI baseadas em papeis temáticos dos verbos; AI baseadas em elementos textuais ativados por nominalizações; AI baseadas em esquemas cognitivos e modelos mentais; AI baseadas em inferências ancoradas no modelo do mundo textual; AI sem antecedente cotextual, estando em jogo não somente estruturas textuais, mas também elementos imersos em contextos de referência. O corpus, em análise, relativo ao fenômeno em estudo, constitui-se de 5 (cinco) narrativas, constantes em 13 (treze) números da Revista Visagens, Assombrações e Encantamentos da Amazônia, de autoria de Monteiro (2000; 2002). Vale esclarecer que os números totais da revista foram editados entre os anos de 1997 a 2004, versando sobre: Boto, Cobra, Matintaperera, Curupira, Lobisomem e Assombrações e Visagens. As análises levam-me a concluir que os processos estudados são constitutivos dessas narrativas, reafirmando-se a premissa de que reconstroem significados simbólicos e sociocognitivos específicos.

[1] AI - Anáfora Indireta.
"País de maricas": negacionismo binário no discurso bolsonarista sobre a covid-19
Authors: Ribeiro dos Santos Cíntia , Ericson Sóstenes 
Published: January 2023

Este artigo tem o objetivo de analisar a memória retomada na declaração do presidente Jair Messias Bolsonaro “Tem que deixar de ser um país de maricas” (2020), referindo-se aos papéis de gênero e de sexualidade no enfrentamento à Covid-19 no Brasil. A partir dos pressupostos teóricos inscritos na Análise do Discurso, inaugurada por Michel Pêcheux, tratamos dos efeitos de sentido produzidos a partir da afirmação da masculinidade normativa, como condição de superação da crise de saúde pública responsável pela morte de mais de 670 mil pessoas no Brasil. Interessa demonstrar de que maneira o dizer do presidente Bolsonaro nega a ciência, ao tempo em que precariza e silencia gêneros dissidentes do padrão binário, num jogo de polarização de sentidos autoritários.
Astragaloside IV (ASIV) Mediates Endothelial Progenitor Cell (EPC)
Exosomal LINC01963 to Inhibit Pyroptosis and Oxidative Stress in
High Glucose-impaired Endothelial Cells
Authors: Xiong Wu , Zhang Xi , Zhou Jian-da , Tan Mei-xin , Liu Yu , Yan Yu , Lei Hua-Juan , Peng Jia-rui , Liu Wei , Tan Pei 
Published: January 2023

Background:
Hyperglycemia is widespread in the world’s population, increasing
the risk of many diseases. This study aimed to explore the regulatory effect
and mechanism of astragaloside IV (ASIV)-mediated endothelial progenitor cells
(EPCs) exosomal LINC01963 in endothelial cells (HUVECs) impaired by high glucose.

Methods:
Morphologies of exosomes were observed by light microscope and electron
microscope. Immunofluorescence was used to identify EPCs and detect the expressions
of caspase-1. LINC01963 was detected by quantitative reverse transcription
PCR. NLRP3, ASC, and caspase-3 were detected by Western Blot. Nanoparticle tracking
analysis was carried out to analyze the exosome diameter. High-throughput sequencing
was applied to screen target lncRNAs. The proliferation of endothelial cells
was measured by cell counting kit-8 assay. The apoptosis level of HUVECs was detected
by flow cytometry and TdT-mediated dUTP Nick-End labeling. The levels of IL-
1β, IL-18, ROS, SOD, MDA, and LDH were measured by enzyme-linked immunosorbent
assay.

Results:
ASIV could promote the secretion of the EPC exosome. LINC01963 was
obtained by high-throughput sequencing. It was observed that high glucose could inhibit
the proliferation, reduce the level of SOD, the expression of NLRP3, ASC, and
caspase-1, increase the levels of IL-1β, IL-18, ROS, MDA, and LDH, and promote
apoptosis of HUVECs. Whereas LINC01963 could inhibit the apoptosis of HUVECs,
the increase the expression of NLRP3, ASC, and caspase-1, and decrease the levels
of IL-1β, IL-18, ROS, MDA, and LDH.

Conclusion:
EPCs exosomal LINC01963 play an inhibitory role in high glucoseinduced
pyroptosis and oxidative stress of HUVECs. This study provides new ideas
and directions for treating hyperglycemia and researching exosomal lncRNAs.
The Outcomes of Surgical and Nonsurgical Treatment in Patients With Spinal Metastases of Lung Cancer: Protocol for a Prospective Cohort Study
Authors: Hu Panpan , Zhai Shuheng , Liu Xiaoxie , Chu Hongling , Wei Feng 
Published: January 2023

Background
Spinal metastases of lung cancer (SMLC) usually have a high degree of malignancy and require multimodality treatment. Patients with SMLC who experience clinical symptoms (eg, local pain, emerging or potential spinal instability, and progressive neurological dysfunction) require surgical treatment. However, there are discrepancies in the comparison of outcomes between surgical treatment and nonsurgical treatment.

Objective
This paper presents the protocol for a study that aims to compare the clinical outcomes of surgical treatment and nonsurgical treatment for SMLC, explore the prognostic factors of SMLC, and establish a survival prediction model based on these prognostic factors.

Methods
This is a prospective cohort study, with an anticipated sample size of 240 patients (120 patients in the surgical group and 120 patients in the nonsurgical group). We will collect baseline data, including demographic, clinical, and radiological information, as well as data from patient-reported questionnaires. Patients will be followed up at 3, 6, 12, and 24 months after treatment, and survival status will be assessed every 3 months. The primary outcome is the overall survival period. Prognostic factors associated with overall survival will be analyzed by univariate and multivariate Cox proportional hazards regression. Odds ratios with 95% CIs will be presented. Statistical significance is set at P<.05.

Results
This study has been approved by our institute’s Medical Science Research Ethics Committee (IRB00006761-M2021085) after a careful audit of the design and content. Patient enrollment began in June 2022 at our hospital. Data collection is expected to be completed by early 2026, and the study results will be published by mid-2027.

Conclusions
In this study, we propose to set up a prospective cohort of patients with SMLC to investigate the outcomes between surgical treatment and nonsurgical treatment. We will explore the role of surgical treatment in SMLC and provide guidance to peer surgeons.

Trial Registration
Chinese Clinical Trial Registry, ChiCTR2100048151; http://www.chictr.org.cn/showproj.aspx?proj=129450

International Registered Report Identifier (IRRID)
DERR1-10.2196/38273
A Medical Assistive Robot for Telehealth Care During the COVID-19 Pandemic: Development and Usability Study in an Isolation Ward
Authors: Wang Ruohan , Lv Honghao , Lu Zhangli , Huang Xiaoyan , Wu Haiteng , Xiong Junjie , Yang Geng 
Published: January 2023

Background
The COVID-19 pandemic is affecting the mental and emotional well-being of patients, family members, and health care workers. Patients in the isolation ward may have psychological problems due to long-term hospitalization, the development of the epidemic, and the inability to see their families. A medical assistive robot (MAR), acting as an intermediary of communication, can be deployed to address these mental pressures.

Objective
CareDo, a MAR with telepresence and teleoperation functions, was developed in this work for remote health care. The aim of this study was to investigate its practical performance in the isolation ward during the pandemic.

Methods
Two systems were integrated into the CareDo robot. For the telepresence system, a web real-time communications solution is used for the multiuser chat system and a convolutional neural network is used for expression recognition. For the teleoperation system, an incremental motion mapping method is used for operating the robot remotely. A clinical trial of this system was conducted at First Affiliated Hospital, Zhejiang University.

Results
During the clinical trials, tasks such as video chatting, emotion detection, and medical supplies delivery were performed via the CareDo robot. Seven voice commands were set for performing system wakeup, video chatting, and system exiting. Durations from 1 to 3 seconds of common commands were set to improve voice command detection. The facial expression was recorded 152 times for a patient in 1 day for the psychological intervention. The recognition accuracy reached 95% and 92.8% for happy and neutral expressions, respectively.

Conclusions
Patients and health care workers can use this MAR in the isolation ward for telehealth care during the COVID-19 pandemic. This can be a useful approach to break the chains of virus transmission and can also be an effective way to conduct remote psychological intervention.
PROGRAMA DE COLETA SELETIVA SOLIDÁRIA: INSTRUMENTOS DE EDUCAÇÃO AMBIENTAL NA ANÁLISE QUALI-QUANTITATIVA DE MATERIAIS RECICLÁVEIS COLETADOS EM UMA IES DA AMAZÔNIA BRASILEIRA
Authors: Braga Risete Maria Queiroz Leão , Teles Ana Isabela Lobato , França Samara Avelino de Souza , Araújo Maria Ludetana , Yoshino Gabriel Hiromite , Almeida Lúcia 
Published: January 2023

A geração de resíduos sólidos e sua disposição final ambientalmente correta têm sido alguns dos maiores desafios enfrentados atualmente no mundo e tem levado a criação de novas políticas públicas para melhorar a gestão e o gerenciamento destes resíduos. No Brasil se destaca o Decreto nº 5.940/2006, que estabelece a implantação da Coleta Seletiva Solidária (CSS) nas instituições públicas federais. Na Cidade Universitária Prof. José da Silveira Netto – Universidade Federal do Pará (UFPA), a CSS é de responsabilidade da Prefeitura Multicampi, que encaminha os materiais recicláveis recolhidos dos Locais de Entrega Voluntária (LEV) da Instituição para associações e cooperativas de catadores de materiais recicláveis da Região Metropolitana de Belém (RMB). O objetivo deste estudo foi avaliar quali-quantitativamente os materiais recicláveis constantes nos LEV da UFPA em três períodos, 2015, 2018 e 2019; analisar os resultados de ações de educação ambiental desenvolvidas nesse período; e estimar o valor bruto com a sua possível comercialização. Os resultados revelaram que a parcela de papel/papelão foi a mais significativa em termos de quantidade em relação aos demais materiais recicláveis. O valor bruto estimado para a comercialização de três categorias de material reciclável (papel/papelão, plástico e metal), pelas associações e cooperativas em 2019, foi de quase R$ 30,000.00 (trinta mil reais).
New Strategies for Inhibition of Listeria monocytogenes and Klebsiella pneumoniae Biofilm Formation and Persistence
Authors: Jastaniah Samyah D. , Jamal Taghreed Yasir , Amashah Reda H. , Aly Magda M. 
Published: January 2023

Objective: This study aimed to find new strategies for the prevention of bacterial biofilms and investigate the effect of some plant extracts on the biofilm formation by certain pathogenic bacterial strains in-vitro.
Methods: Fourteen different biofilm forming bacterial isolates were collected and their biofilm were quantitatively measured under different temperature, pH and growth medium using Crystal violet staining method. Exopolysaccharides (EPS) produced by the isolates were estimated and a comparison between the tested isolates was made. The effect of some plant extracts on bacterial growth, biofilm formation and exopolysaccharide quantity was determined.
Results: The two isolates, Listeria monocytogenes (ATCC13932) and Klebsiella pneumoniae (ATCC700613) were among the most active biofilm forming bacterial isolates. The optimum temperature, pH and media for EPS production and biofilm formation were determined. The effect of some plant extracts of Cranberry; Pomegranate peel and, Arak on growth and formation of biofilm and EPS were recorded. Moreover, minimum inhibition concentration of each plant extract was performed.
Conclusion: EPS quantity produced from the tested isolates depends on some effective factors such temperature, media contents and pH. Aqueous-Cranberry, aqueous-Pomegranate Peel and methanolic-Arak extracts have antibacterial and antibiofilm activities on L. monocytogenes and K. pneumonia. Thus, application of new natural approaches for inhibiting bacterial biofilm is important to prevent persistent and recurrent biofilm related infections.