bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Bright and Dark Sides of a Central Bank's Financial Support to Local Banks after a Natural Disaster: Evidence from the Great Kanto Earthquake, 1923 Japan
Authors: OKAZAKI TETSUJI , OKUBO TOSHIHIRO , STROBL ERIC 
Published: February 2023

AbstractThe Great Kanto Earthquake of 1923 caused serious damage to firms and banks in Yokohama City. We explore the role of the financial support by the Bank of Japan (BoJ) through local banks in a firm's survival and recovery from the natural disaster. We find that the small‐ and medium‐sized firms (SMEs) that had a relatively large correspondent bank with a large number of bills rediscounted by BoJ had a higher likelihood of survival but lower growth after the earthquake. Liquidity supply by the central bank for recovery from a negative shock can have both positive and negative impacts.
Cell proliferation and glial cell marker expression in the wall of the third ventricle in the tuberal region of the male mouse hypothalamus during postnatal development
Authors: Coutteau‐Robles Adrian , Prevot Vincent , Sharif Ariane 
Published: February 2023

AbstractThe third ventricle (3 V) wall of the tuberal hypothalamus is composed of two types of cells; specialized ependymoglial cells called tanycytes located ventrally and ependymocytes dorsally, which control the exchanges between the cerebrospinal fluid and the hypothalamic parenchyma. By regulating the dialogue between the brain and the periphery, tanycytes are now recognized as central players in the control of major hypothalamic functions such as energy metabolism and reproduction. While our knowledge of the biology of adult tanycytes is progressing rapidly, our understanding of their development remains very incomplete. To gain insight into the postnatal maturation of the 3 V ependymal lining, we conducted a comprehensive immunofluorescent study of the mouse tuberal region at four postnatal ages (postnatal day (P) 0, P4, P10, and P20). We analyzed the expression profile of a panel of tanycyte and ependymocyte markers (vimentin, S100, connexin‐43 [Cx43], and glial fibrillary acidic protein [GFAP]) and characterized cell proliferation in the 3 V wall using the thymidine analog bromodeoxyuridine. Our results show that most changes in marker expression occur between P4 and P10, with a switch from a 3 V mostly lined by radial cells to the emergence of a tanycytic domain ventrally and an ependymocytic domain dorsally, a drop in cell proliferation and increased expression of S100, Cx43, and GFAP that acquire a mature profile at P20. Our study thus identifies the transition between the first and the second postnatal week as a critical time window for the postnatal maturation of the 3 V wall ependymal lining.
Synchrony in parent‐offspring social interactions across development: A cross‐species review of rodents and humans
Authors: Ham Gao Xiang , Lim Kai En , Augustine George J. , Leong Victoria 
Published: February 2023

AbstractIn humans, parent–child neural synchrony has been shown to support early communication, social attunement and learning. Further, some animal species (including rodents and bats) are now known to share neural synchrony during certain forms of social behaviour. However, very little is known about the developmental origins and sequelae of neural synchrony, and whether this neural mechanism might play a causal role in the control of social and communicative behaviour across species. Rodent models are optimal for exploring such questions of causality, with a plethora of tools available for both disruption/induction (optogenetics) and even mechanistic dissection of synchrony‐induction pathways (in vivo electrical or optical recording of neural activity). However, before the benefits of rodent models for advancing research on parent‐infant synchrony can be realised, it is first important to address a gap in understanding the forms of parent‐pup synchrony that occur during rodent development, and how these social relationships evolve over time. Accordingly, this review seeks to identify parent‐pup social behaviours that could potentially drive or facilitate synchrony and to discuss key differences or limitations when comparing mouse to human models of parent‐infant synchrony. Uniquely, our review will focus on parent‐pup dyadic social behaviours that have particular analogies to the human context, including instrumental, social interactive and vocal communicative behaviours. This review is intended to serve as a primer on the study of neurobehavioral synchrony across human and rodent dyadic developmental models.
The Gender Gap in Housing Returns
Authors: GOLDSMITH‐PINKHAM PAUL , SHUE KELLY 
Published: February 2023

ABSTRACTUsing detailed transactions data across the United States, we find that single women earn 1.5 percentage points lower annualized returns on housing relative to single men. Forty‐five percent of the gap is explained by transaction timing and location. The remaining gap arises from a 2% gender difference in execution prices at purchase and sale. Consistent with a negotiation channel, women list for less and experience worse negotiated discounts. The gender gap shrinks in tight markets, where negotiation is replaced by quasi‐auctions. Overall, gender differences in housing explain 30% of the gender gap in wealth accumulation for the median household.
Do Municipal Bond Dealers Give Their Customers “Fair and Reasonable” Pricing?
Authors: GRIFFIN JOHN M. , HIRSCHEY NICHOLAS , KRUGER SAMUEL 
Published: February 2023

ABSTRACTMunicipal bonds exhibit considerable retail pricing variation, even for same‐size trades of the same bond on the same day, and even from the same dealer. Markups vary widely across dealers. Trading strongly clusters on eighth price increments, and clustered trades exhibit higher markups. Yields are often lowered to just above salient numbers. Machine learning estimates exploiting the richness of the data show that dealers that use strategic pricing have systematically higher markups. Recent Municipal Securities Rulemaking Board rules have had only a limited impact on markups. While a subset of dealers focus on best execution, many dealers appear focused on opportunistic pricing.
Partner psychological abuse: Can you leave home at work?
Authors: Thompson Merideth J. , Hackney Kaylee , Crawford Wayne , Bonner Julena M. , Carlson Dawn S. 
Published: February 2023

AbstractUtilizing sociometer theory, we examine the impact of partner psychological abuse at home on an individual's self‐esteem and the resulting effects on job performance in the work domain. Further, we propose that the respondent's ability to psychologically detach from family will buffer those effects. Using a sample of dual‐career married couples, we use the actor–partner interdependence model to test this for both individuals in the couple (176 men and 176 women) and find that psychological abuse by one's partner at home diminishes the target's self‐esteem and contributes to reduced job performance and that psychological detachment from family moderated the effect of psychological abuse on self‐esteem for men only, such that men are able to detach and buffer the effects of abuse on their job performance. Implications for practice and future research are discussed.
Relational consequences of stigma: Bridging research on social stigma with relationship science
Authors: Doyle David Matthew , Barreto Manuela 
Published: February 2023

AbstractResearch on the relational effects of stigma must move beyond the intergroup context and, most importantly, focus upon the ways in which stigma itself shapes social relationships. In order to more deeply investigate the relational consequences of social stigma, researchers interested in this topic need to consider the potential contributions of relationship science. Drawing upon past theory, we pose four overarching questions that may help bridge research on social stigma with relationship science: (1) What types of relationships are relevant to understanding the social consequences of stigma? (2) How do relationships operate when partners are faced with social stigma? (3) What psychosocial tendencies do people whose identities are stigmatized bring to their relationships? (4) How does the broader social context affect relationships for members of stigmatized groups? We also consider methodological advances from relationship science, broadly defined, that may progress research in this area. Finally, we highlight the importance of eliminating discriminatory policy as well as introducing policy aimed at remediating social inequalities to ensuring equity in social health between members of stigmatized and dominant groups. It is our aim to point toward a framework for scholars to further push the boundaries in understanding the social consequences of stigma.
A chaperonin containing T‐complex polypeptide‐1 facilitates the formation of the PbWoxT1‐PbPTB3 ribonucleoprotein complex for long‐distance RNA trafficking in Pyrus betulaefolia
Authors: Wang Shengnan , Duan Xuwei , Wang Shengyuan , Hao Li , Zhang Yi , Xu Chaoran , Yu Yunfei , Xiang Ling , Jiang Feng , Heinlein Manfred , Li Tianzhong , Zhang Wenna 
Published: February 2023

Summary
Numerous plant endogenous mRNAs move via phloem and thus affect the growth and development of long‐distant organs. mRNAs are transported with RNA‐binding proteins forming a ribonucleoprotein complex. However, it remains elusive how such RNP complex assembles and facilitates mRNA trafficking.
Protease digestion and RNA immunoprecipitation were used to investigate the RNP assembly function of the complete Chaperonin Containing T‐complex Polypeptide‐1. In situ hybridization, hairy root transformation, microprojectile bombardment, and grafting experiments demonstrate the role of CCT complex in the transport of a PbWoxT1‐PbPTB3 RNP complex in Pyrus betulaefolia.
PbCCT5 silenced caused defective movement of GFP‐PbPTB3 and GFP‐PbWoxT1 from hairy roots to new leaves via the phloem. PbCCT5 is shown to interact with PbPTB3. PbCCT complex enhanced PbPTB3 stabilization and permitted assembly of PbWoxT1 and PbPTB3 into an RNP complex. Furthermore, silencing of individual CCT subunits inhibited the intercellular movement of GFP‐PbPTB3 and long‐distance trafficking of PbWoxT1 and PbPTB3 in grafted plants.
Taken together, the CCT complex assembles PbPTB3 and PbWoxT1 into an RNP complex in the phloem in order to facilitate the long‐distance trafficking of PbWoxT1 in P. betulaefolia. This study therefore provides important insights into the mechanism of RNP complex formation and transport.
Insights into the convergent evolution of fructan biosynthesis in angiosperms from the highly characteristic chicory genome
Authors: Shen Fei , He Hao , Huang Xin , Deng Yang , Yang Xiaozeng 
Published: February 2023

Summary
Fructans in angiosperms play essential roles in physiological functions and environmental adaptations. As a major source of industrial fructans (especially inulin‐type), chicory (Cichorium intybus L.) is a model species for studying fructan biosynthesis. However, the genes underlying this process and their evolutionary history in angiosperms remain elusive.
We combined multiple sequencing technologies to assemble and annotate the chicory genome and scan its (epi)genomic features, such as genomic components, DNA methylation, and three‐dimensional (3D) structure. We also performed a comparative genomics analysis to uncover the associations between key traits and gene families.
We achieved a nearly complete chicory genome assembly and found that continuous bursts of a few highly active retrotransposon families largely shaped the (epi)genomic characteristics. The highly methylated genome with its unique 3D structure potentially influences critical biological processes. Our comprehensive comparative genomics analysis deciphered the genetic basis for the rich sesquiterpene content in chicory and indicated that the fructan‐accumulating trait resulted from convergent evolution in angiosperms due to shifts in critical sites of fructan‐active enzymes.
The highly characterized chicory genome provides insight into Asteraceae evolution and fructan biosynthesis in angiosperms.
Catsnap: a user‐friendly algorithm for determining the conservation of protein variants reveals extensive parallelisms in the evolution of alternative splicing
Authors: Timofeyenko Ksenia , Kanavalau Dzmitry , Alexiou Panagiotis , Kalyna Maria , Růžička Kamil 
Published: February 2023

Summary

Understanding the evolutionary conservation of complex eukaryotic transcriptomes significantly illuminates the physiological relevance of alternative splicing (AS). Examining the evolutionary depth of a given AS event with ordinary homology searches is generally challenging and time‐consuming.

Here, we present Catsnap, an algorithmic pipeline for assessing the conservation of putative protein isoforms generated by AS. It employs a machine learning approach following a database search with the provided pair of protein sequences.

We used the Catsnap algorithm for analyzing the conservation of emerging experimentally characterized alternative proteins from plants and animals. Indeed, most of them are conserved among other species. Catsnap can detect the conserved functional protein isoforms regardless of the AS type by which they are generated. Notably, we found that while the primary amino acid sequence is maintained, the type of AS determining the inclusion or exclusion of protein regions varies throughout plant phylogenetic lineages in these proteins. We also document that this phenomenon is less seen among animals.

In sum, our algorithm highlights the presence of unexpectedly frequent hotspots where protein isoforms recurrently arise to carry physiologically relevant functions. The user web interface is available at https://catsnap.cesnet.cz/.
Plant water use theory should incorporate hypotheses about extreme environments, population ecology, and community ecology
Authors: Blonder Benjamin Wong , Aparecido Luiza Maria Teophilo , Hultine Kevin R. , Lombardozzi Danica , Michaletz Sean T. , Posch Bradley C. , Slot Martijn , Winter Klaus 
Published: February 2023

SummaryPlant water use theory has largely been developed within a plant‐performance paradigm that conceptualizes water use in terms of value for carbon gain and that sits within a neoclassical economic framework. This theory works very well in many contexts but does not consider other values of water to plants that could impact their fitness. Here, we survey a range of alternative hypotheses for drivers of water use and stomatal regulation. These hypotheses are organized around relevance to extreme environments, population ecology, and community ecology. Most of these hypotheses are not yet empirically tested and some are controversial (e.g. requiring more agency and behavior than is commonly believed possible for plants). Some hypotheses, especially those focused around using water to avoid thermal stress, using water to promote reproduction instead of growth, and using water to hoard it, may be useful to incorporate into theory or to implement in Earth System Models.
Comparison of Long‐Term Clinical and Radiographical Outcomes between the Anterior and Combined Anterior and Posterior Approaches for Treating Lumbosacral Tuberculosis
Authors: Zhang Zhuang , Hu Bo‐wen , Wang Lin‐nan , Li Tao , Yang Hui‐liang , Liu Li‐min , Song Yue‐ming , Zhou Zhong‐jie 
Published: February 2023

ObjectiveBoth anterior and combined anterior and posterior approaches have been used to treat lumbosacral tuberculosis. However, long‐term follow‐up studies of each approach have not been conducted. We aimed to compare the long‐term clinical and radiographical outcomes between the two approaches.MethodsIn this retrospective cohort study, we included 49 patients with a minimum 6‐year follow‐up between January 2008 and March 2012. Twenty‐four patients underwent the anterior approach (anterior group), and 25 underwent the combined anterior and posterior approach (anterior–posterior group). Student's t test, Mann–Whitney U test, and Pearson's chi‐square test were used to compare the two groups regarding clinical data, such as visual analogue scale scores, Oswestry disability index scores and neurological status, and radiographical data, such as lumbosacral angle, lumbar lordosis, and L5‐S1 height. Furthermore, operative time, length of stay, and intraoperative and postoperative blood loss (IBL, PBL) were recorded.ResultsBoth groups had satisfactory clinical and radiographical outcomes until the final follow‐up. All patients achieved bony fusion, and no group differences were found in any of the clinical indices. Both groups corrected and maintained the lumbosacral angle, lumbar lordosis, and L5‐S1 height. However, the operative time, length of stay, maximum Hb drop, IBL, and PBL of the anterior group (140.63 ± 24.73 min, 12.58 ± 2.45 days, 28.33 ± 9.70 g/L, 257.08 ± 110.47 ml, and 430.60 ± 158.27 ml, respectively) were significantly lower than those of the anterior–posterior group (423.60 ± 82.81 min, P < 0.001; 21.32 ± 3.40 days, P < 0.001; 38.48 ± 8.03 g/L, P < 0.001; 571.60 ± 111.04 ml, P < 0.001; and 907.01 ± 231.99 ml, P < 0.001).ConclusionThis retrospective study demonstrated long‐term efficacy of the anterior approach with a single screw fixation, which was as effective as that of the combined anterior and posterior approach, with the advantage of less trauma.
Clinical outcomes of subcutaneous implantable cardiac defibrillator implantation – Iran SICD registry
Authors: Mehdinejadshani Mahdiye , Fallah Hamidreza , Kamali Farzad , Alizadeh‐Diz Abolfath , Eslami Masoud , Golabchi Allahyar , Taherpour Mehdi , Shahabi Javad , Mollazadeh Reza , Madadi Shabnam , Azhari Amir , Sodagar Abdolhossein , Eftekharzadeh Mahmoud , Oraii Saeed , Fazelifar Amirfarjam , Kazemisaeed Ali , Ghorbanisharif Alireza , Dalili Mohammad , Khorgami Mohammadrafie , Heidari‐Bakavoli Alireaza , Jorat Mohammadvahid , Nikoo Hossein , Kheirkhah Jalal , Saravi Mehrdad , Khodaparast Morteza , Mirzaali Mansour , Emkanjoo Zahra , Mirmasoumi Mehrdad , Sadeghian Saeed , Mokhtari Meisam , Hedayati‐Goudarzi Mohammadtaghi , Haghjoo Majid 
Published: February 2023

AbstractBackgroundThe subcutaneous implantable‐defibrillator (S‐ICD) is a relatively new alternative to the transvenous ICD system to minimize intravascular lead‐related complications. This paper presents outcome of SICD implantation in patients enrolled in Iran S‐ICD registry.MethodsBetween October 2015 and June 2022, this prospective multicenter national registry included 223 patients with a standard indication for an ICD, who neither required bradycardia pacing nor needed cardiac resynchronization to evaluate the early post‐implant complications and long‐term follow‐up results of the S‐ICD system.ResultsThe mean age of the patients was 45 ± 17 years. The majority (79.4%) were male. Ischemic cardiomyopathy (39.5%) was the most common underlying disorder among patients selected for S‐ICD implant. Most study patients (68.6%) had ICD for primary prevention of sudden cardiac death. Seven patients (3.1%) were found to have suboptimal lead positions. Six patients (2.7%) developed a pocket hematoma; all were managed medically. During a mean follow‐up of 2 years, the appropriate therapy was recorded in 13% of the patients and inappropriate ICD intervention mainly due to supraventricular tachycardia in 8.9%. Pocket infection was observed in four patients (1.8%) and five patients (2.2%) died mainly due to heart failure.ConclusionS‐ICDs were effective at detecting and treating both induced and spontaneous ventricular arrhythmias. Major clinical complications were rare.
A novel R2R3‐MYB transcription factor FaMYB5 positively regulates anthocyanin and proanthocyanidin biosynthesis in cultivated strawberries (Fragaria × ananassa)
Authors: Jiang Leiyu , Yue Maolan , Liu Yongqiang , Zhang Nating , Lin Yuanxiu , Zhang Yunting , Wang Yan , Li Mengyao , Luo Ya , Zhang Yong , Wang Xiaorong , Chen Qing , Tang Haoru 
Published: February 2023

SummaryFlavonoids have a major contribution to the fruit quality in cultivated strawberries and are regulated by MYB, bHLH and WD40 transcriptional factors. We reported here the identification of the FaMYB5, an R2R3‐MYB transcription factor, which positively regulated the accumulation of anthocyanins and proanthocyanidins through the trans‐activation of the F3'H and LAR. The strawberry FaEGL3 and FaLWD1/FaLWD1‐like interact with the R2R3‐FaMYB5 to form an MYB‐bHLH‐WD40 complex (MBW), enhancing the regulatory efficiency. The R2R3‐FaMYB5 was constitutively expressed in various tissues and in fruits of different developmental stages, which was strikingly contrasting to the fruit‐specific expression patterns of FaMYB10. Meanwhile, R2R3‐FaMYB5 failed to promote a stable accumulation of anthocyanin glycosides in the mature fruits of the myb10 mutant, mainly due to the suppressed expression of TT19. The R2R3‐FaMYB5 was regulated by an antisense long noncoding RNA lncRNA‐myb5. Additionally, the R2R3‐FaMYB5 protein could interact with FaBT2 and was degraded through the ubiquitin/26 S proteasome pathway. Transcriptome and metabolome data showed that R2R3‐FaMYB5 enhanced the gene expression and the metabolite accumulation involved in the flavonoid, phenylpropanoid and lignin biosynthesis pathways. Collectively, we conclude that the FaMYB5 is an R2R3‐MYB activator involved in the composition of MBW, which positively regulates the biosynthesis of anthocyanin and proanthocyanidin. These findings provided new insights into the molecular mechanisms that regulate flavonoids in strawberry fruits.
Temporal trends in primary payers in pediatric heart transplant and association with long‐term survival
Authors: Restaino Kathryn , Zhang Xuemei , Faerber Jennifer A. , Rossano Joseph W. , Burstein Danielle , Wittlieb‐Weber Carol A. , Lin Kimberly Yee , Edelson Jonathan B. , Edwards Jonathan J. , O'Connor Matthew J. 
Published: February 2023

AbstractBackgroundPediatric heart transplantation (HT) is resource intensive. In adults, there has been an increase in the proportion of HTs funded by public insurance, with post‐HT outcomes inferior to those funded by private sources. Trends in the funding of pediatric HT and outcomes in children have not been described.MethodsWe queried the United Network for Organ Sharing (UNOS) database for children (<18 years) listed for and undergoing HT between 2004 and 2021. We identified the primary payer at listing, HT, 1 year, and 1–5 years following HT. Trends were analyzed using generalized logit models. Multivariable‐extended Cox regression models were used to test the relationship between insurance type at the time of transplant and time to death or re‐transplant.ResultsThere were 6382 pediatric patients who underwent transplants and had either public or private insurance at the time of transplant. The percentage of patients with public insurance at the time of HT increased over time. Public insurance at the time of HT was associated with an increased risk of death or re‐transplant beyond 2 months after HT (adjusted HR at 6 months = 1.43, 95% CI: 1.13–1.81, p = .003; adjusted HR at 9 months = 1.67, 95% CI: 1.17–2.37, p = .004).ConclusionThere has been a statistically significant trend toward increasing public insurance for children awaiting, at the time of, and after HT. Black patients and those with public insurance at HT have worse long‐term outcomes. This study highlights ongoing disparities in pediatric HT and the need to focus efforts on achieving equitable outcomes.