bluuebunny/crossref_metadata_2025_split huggingface dataset:
Glutathione peroxidase and superoxide dismutase as markers of brain dysfunction in adolescents with diabetic ketoacidosis
Authors: Bykov Yu. B. 
Published: August 2023

Introduction. Diabetic ketoacidosis (DKA) is the most prevalent and severe acute complication of type 1 diabetes mellitus (DM) in children and adolescents. Oxidative stress (OS) is viewed on the one hand as a possible pathophysiological element in the development of this complication, and on the other, as an important factor that triggers the development of cerebral insufficiency in patients with type 1 DM.Aim: to study the content of antioxidant enzymes in adolescents with type 1 DM in the setting of DKA and determine the correlation between the concentration of glutathione peroxidase (GP) and superoxide dismutase (SOD) and brain dysfunction after the manifestation of DKA.Materials and methods. The study involved 52 adolescents (mean age − (16.7±1.25) years), of whom 26 were patients with type 1 DM complicated by DKA (study group; duration of disease − (6.5±0.46) years) and 26 were apparently healthy adolescents (control group). Cognitive functioning was assessed using the Montreal Cognitive Assessment (MoCA) test. Concentration of GP and SOD was assessed in serum samples by ELISA. Mann-Whitney test was used to assess differences between means, and Spearman’s coefficient was used to calculate correlations.Results. Assessment using the MoCA tool showed a statistically significant cognitive decline in adolescents who had an episode of DKA (p = 0.0001). Another statistically significant finding in DKA was the lower mean levels of both GP (p = 0.0031) and SOD (p = 0.0173). Negative correlation was discovered between values obtained in the MoCA test and duration of disease and number of hospital admissions with DKA, and between GP levels and number of admissions with DKA, as reflected in patient history. Positive correlation was discovered between GP and SOD levels and values obtained in the MoCA test.Discussion. Patients were found to have decreased antioxidant defense, along with brain dysfunction, after the manifestation of DKA. DKAassociated impairment of antioxidant defense is one of the pathophysiological mechanisms underpinning the development of cognitive dysfunction in adolescents with type 1 DM. Conclusion GP and SOD can be viewed as markers of DKA-associated brain dysfunction in patients with type 1 DM.
Perioperational management of elderly and senile patients based on a comprehensive geriatric assessment for endoprosthetics of large joint
Authors: Khisomov K. Kh. , Ondar V. S. , Khisomov H. K. 
Published: August 2023

Introduction. Due to the changing age structure of the world’s population, an increase in the number of geriatric patients undergoing endoprosthetics of large joints is to be expected in the future. Age-related frailty and existing comorbidities pose problems for the entire treatment team.The aim of the study was to determine the effectiveness of comprehensive geriatric management of elderly and senile patients before and after endoprosthetic of the hip and knee joints.Materials and methods. An analysis of publications on the use of comprehensive in endoprosthetic of large joints in elderly and senile patients with osteoarthritis was performed. Searched in the electronic databases and libraries Web of Science, Conchrane library, PubMed, eLibrary using the search words: comprehensive geriatric assessment.Results and discussion. There is an increasing incidence of large joints endoprosthetic in orthogeriatric patients with osteoarthritis. Anaesthesia and arthroplasty in this group of patients is an important issue, as well as ensuring immediate postoperative mobilization of the patient. An individualized patient preparation plan for surgical intervention and postoperative management, aimed at preventing the development of transient cognitive impairment and other complications associated with geriatric status, in particular falls, is a necessary organizational element of treatment.Conclusion. A comprehensive geriatric assessment plays a crucial role in the perioperative introduction of geriatric patients for endoprosthetic of large joints. Timely identification of geriatric patients during the preoperative phase eliminates risk factors.
The Effect of Wall Shooting Exercise Using the Beef Concept on Free Throw Shooting Accuracy in High School Women Students
Authors: Angela M Enna 
Published: August 2023

The purpose of the study. This research was motivated by the results of the free throw performed by the women's basketball extracurricular which was not optimal and not appropriate in its implementation. free throw is the accuracy of the direction of the ball shot towards the ring, where this shot is taken from behind the free throw line in a basketball game.
Materials and methods. Methods This research uses an experimental method with One Group, namely Pre-test and Post-test Design. The data collection technique was saturated sampling with inclusion and exclusion criteria. Data analysis in this study used the Wilcoxon test, Paired Sample T-test.
Results. Data analysis in this study used the Wilcoxon test, Paired Sample T-test. Research results based on the statistical output "Test Statistics", it is known that Asymp.Sig (2-tailed) is worth 0.001. Because the value of 0.001 is smaller than <0.05.
Conclusions. The conclusion in this study is that there is a significant effect between the beef concept wall shooting exercise method on the extracurricular free throw ability of SMAN 1 bangkinang city.
Emission Characterization of Petrol, Ethanol and Spent Engine Oil Blends for Two-Stroke Spark Ignition Engine
Authors: Nasir Lawal Muhammed , Ogbeide-Igiebor Victor , Ozigis Idris Ibrahim 
Published: August 2023

Exhaust emission has remained a big global concern in atmospheric change, and has thus, lead to stiffer polices on emission. To achieve the set emission targets different fuel mix and combustion process are continuously been investigated. This work is used to practically model the condition of a two-stroke engine that has run over time whose used lubricating oil finds its way from the sump to the combustion chamber and thus resulting to greater rate of incomplete combustion and higher emission. An exhaust analyser with a deep probe was deployed to access the out-going burnt gasses from a two-stroke spark ignition engine that is fed with multi blends of petrol, ethanol and spent engine oil. The characteristics of the emission constituents were investigated and compared to the global limits set by different organizations such as California Air Resources Board, Environmental Protection Agency in USA, International Council on Clean Transportation, Road Transport Bureau- in Japan, and European Emission Standard Agency, among others. The result shows an increase in , and emissions with samples that contain spent oil as against those with new engine oil which is also more effective. It was also found that samples with higher quantity of ethanol show lower emission of , and gases. This is likely due to interstation of ethanol molecules with that of the spent oil, thus making it more potent for further combustion. This was also supported with the fact that emission was higher in blends with higher quantity of ethanol. Thus, the presence of ethanol in fuel blend used in two-stroke spark ignition engine may be considered to be a source of improvement in combustion and hence a means of reducing emission in two-stroke port operated spark ignition engines.
Problems of educational impact on convicts to punishments without isolation from community
Authors: Гета М.Р. , Смирнов А.Н. 
Published: August 2023

В статье рассматриваются пробелы регулирования нормами отечественного уголовно-исполнительного законодательства воспитательно-профилактического воздействия на осужденных к наказаниям без изоляции от общества. Будучи одним из средств исправления осужденных и совокупностью социальных и психолого-педагогических технологий, воспитательная работа с осужденными к наказаниям без лишения свободы нуждается в закреплении правовых форм, оснований и порядка ее осуществления. Упоминание о воспитательной работе с осужденными к альтернативным наказаниям в нормах УИК РФ носит декларативный характер и не сопровождается организационно-правовым механизмом ее реализации. Нет его и в ведомственных подзаконных актах, посвященных уголовно-исполнительной деятельности. Авторы предлагают преодолеть данный пробел в уголовно-исполнительном регулировании с учетом накопленного отечественной пенитенциарной наукой опыта и исходя из социально-правового смысла исполнения уголовных наказаний.
The article discusses the problems of regulation by the norms of domestic penal enforcement legislation of educational and preventive impact on those sentenced to punishment without isolation from society. Being one of the means of correction of convicts and a set of social and psychological-pedagogical technologies, educational work with convicts sentenced to punishment without deprivation of liberty needs to consolidate the legal forms, grounds and procedure for its implementation. The mention of educational work with those sentenced to alternative punishments in the norms of the Criminal Code of the Russian Federation is declarative and is not accompanied by an organizational and legal mechanism for its implementation. It is not included in departmental by-laws on penal enforcement activities. The authors propose to overcome this gap in the penal regulation, taking into account the experience accumulated by the domestic penitentiary science and proceeding from the socio- legal meaning of the criminal penalties.
Prevention of group offenses of convinced in educational colonies: organizational aspect
Authors: Каретников К.В. 
Published: August 2023

В статье подвергаются анализу вопросы организации профилактики групповых правонарушений осужденных в воспитательных колониях ФСИН России. Констатируется, что организационные основы профилактической деятельности учреждений и органов уголовно-исполнительной системы представлены в ведомственных нормативных правовых актах в усеченном формате, который не позволяет в условиях воспитательных колоний имеющимися силами и средствами уменьшить объем противоправных проявлений со стороны несовершеннолетних осужденных, а также ликвидировать влияние криминальной субкультуры на незрелую личность подростков. Обосновывается важность и значимость организации профилактики групповых правонарушений осужденных в воспитательных колониях в системе профилактики. Раскрываются положения нормативных правовых актов федерального и ведомственного характера, касающиеся полномочий таких субъектов профилактики групповых правонарушений осужденных, как центральный аппарат ФСИН России, территориальный орган ФСИН России и администрация воспитательной колонии. Акцентируется внимание на существующих проблемах относительно организации профилактической деятельности воспитательных колоний. Делается вывод о необходимости совершенствования организационных вопросов профилактики групповых правонарушений осужденных в воспитательных колониях ФСИН России, выдвигается ряд предложений, реализация которых будет способствовать, по мнению автора, преодолению существующих недостатков.
This article analyzes the issues of organizing the prevention of group offenses of convicts in educational colonies of the Federal Penitentiary Service of Russia. It is stated that the organizational foundations of the preventive activities of institutions and bodies of the penitentiary system are presented in departmental regulatory legal acts in a truncated format, which does not allow, in the conditions of educational colonies, with the available forces and means, to reduce the volume of illegal manifestations on the part of juvenile convicts, as well as to eliminate the influence of the criminal subculture on the immature personality of adolescents. The importance and significance of organizing the prevention of group offenses of convicts in educational colonies in the prevention system is substantiated. The provisions of normative legal acts of a federal and departmental nature concerning the powers of such subjects for the prevention of group offenses of convicts as the central office of the Federal Penitentiary Service of Russia, the territorial body of the Federal Penitentiary Service of Russia and the administration of an educational colony are disclosed. Attention is focused on the existing problems regarding the organization of preventive activities in educational colonies. The conclusion is made about the need to improve the organizational issues of prevention of group offenses of convicts in educational colonies of the Federal Penitentiary Service of Russia, a number of proposals are put forward that, according to the author, can overcome the existing shortcomings.
ГЛАУКОМАТОЗНЫЕ ПРОЦЕССЫ В УСЛОВИЯХ РЕЗКОКОНТИНЕНТАЛЬНОГО КЛИМАТА: ХРОНОБИОЛОГИЧЕСКИЕ КЛИНИЧЕСКИЕ ОСОБЕННОСТИ И ВОПРОСЫ ПРОГНОЗИРОВАНИЯ
Authors: Ахмедов Нозимбек , Мамасолиев Зохиджон , Маматхужаева Гулнарахан 
Published: August 2023

Представлены хронобиологические, клинические и прогностические оспекты глаукоматозных процессов (ГП) в условиях резкоконтинентального климата Ферганской долины (Андижан) Узбекистана. Проанлизированы 1112 случаев с ГП. Отмечено, что существует прямая коррелятивная связь между метеорологическими факторами (атмосферном давление относительная влажностю воздуха, термическим режимом и солнечным сиянием) и развитнем «офтальмоконтинуума», Флюктация этих факторов является фактором риска развития и прогрессирования ГП.
Sistem Pemerintahan Berbasis Elektronik: Best Practice dari Pemerintah Daerah di Indonesia
Authors: Madya Putra Yaumil Ahad  , Nugraha Barsei Adhityo 
Published: August 2023

Tantangan di era revolusi industri menjadikan seluruh sektor agar dapat memiliki kemampuan beradaptasi dengan cepat dan meninggalkan cara kerja konvensional salah satunya adalah sektor publik. Di Indonesia, salah satu langkah untuk melakukan transfirmasi digital adalah dengan menerapkan kebijakan Sistem Pemerintahan Berbasis Elektronik (SPBE). Peraturan Presiden Nomor 95 Tahun 2018 tentang SPBE memberikan peluang bagi pemerintah untuk melakukan inovasi-inovasi dengan melakukan transformasi layanan digital salah satunya adalah Kabupaten Polewali Mandar. Pemerintah Kabupaten Polewali Mandar menjadi satu-satunya daerah di Indonesia Bagian Timur (Sulawesi, NTT, NTB, Maluku, dan Papua) yang memiliki predikat SPBE “sangat baik” dan masuk dalam 7 besar terbaik nasional dari 483 Provinsi/Kabupaten/Kota yang mengikuti pemantau evaluasi SPBE tahun 2022. Penelitian ini menggunakan pendekatan studi kasus pada Dinas Komunikasi dan Informatika Kabupaten Polewali Mandar untuk mengetahui pelaksanaan collaborative governance dalam implementasi SPBE. Hasil Penelitian menunjukkan bahwa dorongan kolaborasi, pemahaman dan tujuan bersama serta kebijakan menjadi instrumen penting. Serta kunci sukses pelaksanannya adalah komitmen pimpinan, Indeks SPBE terintegrasi dengan IKU di RPJMD, kolaboratif antar OPD serta budaya continuous improvement. Oleh karena itu, Kabupaten Polewali Mandar dapat dijadikan lokus best practice implementasi SPBE di Indonesia khususnya wilayah Indonesia Timur
of Factors Influencing the Managerial Performance of Regional Works Units SKPD) of Banda Aceh City Government
Authors: Sari Dewi Maya , Ikhwal Muhammad , Soufyan Dara Angreka 
Published: August 2023

This study aims to investigate how managerial performance at SKPD Banda Aceh City Goverment is influenced by management control system, public accountability, and clarity of budget targets. The 44 SKPDs in Banda Aceh City, which included organizations, institutions, and offices, made up the study's population. The Head of Service, Head of Finance, Finance Staff, and Secretaries from each SKPD participated in this survey as respondents. There were as many as 176 surveys distributed. There were 152 questionnaires that were returned. A number of linear regressions were used to analyze the data. The study's findings demonstrate that clear budget targets, management control systems, and public accountability all significantly and positively affect managerial performance at SKPD Kota Banda Aceh.
Plant-Based Sustainable Self-Cleaners in Nanotechnology Era: From Mechanism to Assembling
Authors: Nakhaei Mojdeh , Ying Chong Jing , Tang Yunlong , Mansouri Shahnaz 
Published: August 2023

Nature has always been a resource of inspiration for humans, providing valuable lessons that have led to innovative solutions throughout history. Observing the micro-nano roughness structure of bio-surfaces has led to the discovery of natural self-cleaning surfaces for over 25 years. This has sparked a new field of research with valuable applications. Numerous self-cleaning products made from plant extracts have been created by replicating the natural purifying abilities of plant surfaces. Significant literature exists on the development, classification, extraction, and production of self-cleaning agents for diverse industries through a thorough understanding of bio-cleaning mechanisms. Various methods have been developed to synthesize these surfaces, including immersion, electrochemical deposition, emulsion, electrospinning, phase-separation, Chemical-Vapor-Deposition (CVD), spray coating, wet chemical reaction, and three-dimensional printing (3D-printing), among others. Currently, the primary objective is to gain knowledge from nature and utilize it to develop novel products for food, pharmaceutical, and related industries. Natural plant-based self-cleaning surfaces can be characterized by their superhydrophobicity and superhydrophilicity regimes. The process of 3D-printing is a computer-based technique that builds up three-dimensional objects through the layer-by-layer deposition of materials. The creation of effective self-cleaning surfaces with unique wettability, chemical properties, and microstructure depends on the design and engineering of solid surfaces.
What Predictors Explain Holocaust and Human Rights Education in Spain? A Study with in-Service Secondary School Teachers
Authors: Ortega-Sánchez Delfín , Barba-Alonso César 
Published: August 2023

From the perspective of the pedagogy of teaching collective trauma, and the educational dialogue between historical memory and contemporary social responsibility, this research seeks to determine the socio-demographic, formative and didactic factors that explain the teaching of the Holocaust and Human Rights education in a sample of Spanish secondary school teachers (n = 1125). Through a non-experimental, cross-sectional, explanatory and predictive design, and the application of the instrument Teaching the Holocaust and Human Rights Education (THRE), the results obtained show that the initial and on-going training of teachers is one of the explanatory axes of the curricular inclusion of the Holocaust and Human Rights as specific contents of education for democratic citizenship. Age, gender and level of teacher education, on the other hand, are not proposed as explanatory factors for the inclusion of Holocaust and human rights as specific content in education for democratic citizenship.
SARS-COV-2 GENOMIC SURVEILLANCE IN BULGARIA INDICATES DIVERSE DYNAMICS DRIVEN BY MULTIPLE INTRODUCTIONS OF DIFFERENT VIRAL VARIANTS IN 2022
Authors: Alexiev Ivaylo , Ivanov Ivan , Stoikov Ivan , Donchev Deyan , Grigorova Lyubomira , Dimitrova Reneta , Gancheva Anna , Korsun Neli , Trifonova Ivelina , Dobrinov Veselin , Kantardjiev Todor , Christova Iva 
Published: August 2023

Background. Evolution of the emerging SARS-CoV-2 variants raises concerns about the possibility of accelerated transmission, disease severity, diagnostic challenges, and reduced vaccine effectiveness in the ever-evolving COVID-19 pandemic worldwide. Objectives for this study were to build a comprehensive national system for monitoring and genomic surveillance of SARS-CoV-2 and to identify the introduced virus variants in the country.
Methods. We analyzed SARS-CoV-2 infections in 7948 representative clinical samples collected in medical institutions in different geographical regions of the country in 2022. Whole-genome next-generation sequencing of SARS-CoV-2 was performed on samples from randomly selected SARS-CoV-2-positive individuals by using a modified ARTIC v3-tailed amplicon method. A bioinformatic and phylogenetic analyses of the obtained sequences was carried out.
Results. Significant dynamics was observed in the spread of viral variants in 2022, which is characterized by the introduction and spread of multiple SARS-CoV-2 variants. The phylogenomic analysis identified a high genetic heterogeneiety composed of a total of 152 different viral clades divided into 3 main supergroups: 114 (75.0%) of which were Omicron sub-variants, 35 (23.0%) Delta sub-variants, and 3 (2.0%) recombinant forms.
Conclusion. Viral variants and their sub-clades with different potentials to impact disease severity were identified and the information was immediately published for use by decision-makers and the scientific community. The global pandemic of COVID-19 has shown the importance of molecular biological surveillance, which is an indispensable element of the modern approach in the fight against infectious diseases.
مستوى معرفة معلمات التعليم العام باضطراب تشتت الانتباه وفرط الحركة من وجهة
Authors: فاطمة عبد الرحمن الزهراني  
Published: August 2023

This research aims to identify the level of general education teachers' knowledge of attention deficit hyperactivity disorder from their point of view. To achieve this goal, the researcher used the descriptive analytical approach. By applying the questionnaire as a tool for collecting information, on the research sample consisting of (831) public education teachers in the primary stage in Makkah. The results of the first question indicated a low level, with an arithmetic mean (2.22), of general education teachers' knowledge of attention deficit hyperactivity disorder from their point of view. The first dimension (general knowledge of attention deficit hyperactivity disorder) came at a low level, with an arithmetic mean of (2.16), and the second dimension (knowledge of the criteria for diagnosing attention deficit hyperactivity disorder) came at a low level, with an arithmetic mean of (2.27). The results of the second question also indicated that there were no statistically significant differences (α = 0.05) in the knowledge of general education teachers with attention deficit hyperactivity disorder from their point of view because of the variables of years of experience and the educational institution in all dimensions and the total score. The researcher recommends the need to hold training courses and workshops to increase and improve the level of teachers with attention deficit hyperactivity disorder.