bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ambulatory electrocardiographic monitoring in patients with Fabry disease: study design and cohort characterization
Authors: Kotelnikova E. V. , Senchikhin V. N. , Lipchanskaya T. P. 
Published: January 2023

Aim. To develop study design and analyze the characteristics of a cohort of patients with cardiac manifestations of Fabry disease (FD) in order to study the possibilities of electrocardiography (ECG) telemonitoring for screening for cardiac arrhythmias (CA), requiring a change in therapeutic tactics.Material and methods. This prospective cohort study included 11 patients (8 men and 3 women) with documented FD, with cardiac complaints and ECG signs of heart involvement. For ECG telemonitoring, non-invasive digital event recorders ECG Dongle (Nordavind-Dubna, Russia) were used. Primary endpoint was registration of CA requiring a change in therapeutic tactics (implantation of a pacemaker/defibrillator-cardioverter/prescribing anticoagulants). Secondary endpoint was dynamics of monitored parameters for operational correction of the therapeutic regimen.Results. The cohort of patients is predominantly male (73/27%; mean age, 41±13,7 years). At the time of inclusion, 8 (73%) patients received enzyme replacement therapy for 4-73 months. Most patients are active Internet users, are aware of telemedicine possibilities and are interested in remote monitoring. The main complaints were related to cardiac function interruptions, palpitations, and chest discomfort. Left ventricular hypertrophy was diagnosed on ECG in 7 (64%) patients. Echocardiography revealed symmetrical left ventricular hypertrophy in 5 patients, asymmetric interventricular septal hypertrophy in 2 patients. Other echocardiographic abnormalities included valvular heart disease (mitral and tricuspid valve prolapse with mitral and tricuspid regurgitation, presence of supplemental chords) and aortic root dilatation. Initially, the ECG was dominated by sinus rhythm (n=10); 1 patient had documented ventricular tachycardia, 4 patients had single and coupled ventricular premature contractions; supraventricular tachycardia and premature contractions in 2 patients. Four patients had a PR interval shortening without signs of accessory pathways, 1 patient — Wolff-Parkinson-White syndrome, 1 patient — prolonged QTc interval.Conclusion. For effective management of FD, additional multicenter studies are required to develop algorithms for making tactical decisions in the process of cardiac monitoring, taking into account the characteristics of the cardiovascular manifestations of this disease. The article proposes a technology for telemedicine cardiac monitoring using ECG event recorders for outpatient CA screening.
Considerations for Far-field Antennas Test
Authors: Ilnitskyi Ludvig , Sibruk Leonid , Mykhalchuk Inna 
Published: January 2023

The theoretical foundations of testing antenna parameters and characteristics in the far radiation field are presented. A two-beam model of radio wave propagation was used, including a direct wave and a wave reflected from the earth's surface. This model meets the conditions for carrying out measurements on a signals training areas or in an anechoic chamber. It is shown that for a given distance between the antennas, it is necessary to control the dimensions of the aperture transmitting and receiving antennas for the compliance with the maximum permissible values. Formulas for determining the permissible dimensions of the antenna aperture are obtained. The influence of the antenna hanging heights on the measurement accuracy was also investigated. Recommendations for reducing the level of electromagnetic waves reflected from the earth's surface are given.
Evapotranspiration of a Hungarian rice variety, ‘SZV Tünde’ in large weighing lysimeter
Authors: Jancsó Mihály , Székely Árpád , Szalóki Tímea , Lantos Csaba , Valkovszki Noémi Júlia , Bozán Csaba , Pauk János 
Published: January 2023

Aerobic rice production is an alternative growing method to reduce water consumption of rice and thus increase the water productivity of the system without a significant reduction of yield and quality. Evapotranspiration (ETc) of a Hungarian rice variety, ‘SZV Tünde’ under aerobic conditions was measured in large weighing lysimeter during the growing season in 2020. In our experiment, 506.7 g/m2 grain yield and a total above-ground biomass of 1140.4 g/m2 were produced with the application of 315.6 mm of irrigation. Water use-efficiency (WUE) based on the water input and the grain yield was 0.65 g/L. Total ETc for the whole season was measured as 648.3 mm. However, ETc values were ranged 2.04-3.86 mm/day, 3.57-7.90 mm/day and 0.90-4.26 mm/day at the initial, mid and end stages, respectively. Crop coefficients for the different periods of the season were calculated as Kcini=0.82, Kcmid=1.40 and Kcend=0.77. Negative effects of drought can seriously damage rice crop; therefore irrigation scheduling has significant role in successful aerobic rice cultivation. Reliable estimation of evapotranspiration rate in different crop developmental stages can promote this goal.
Immigration Detention, Deportation and Judicial Review in the Age of Covid 19
Authors: Akhtar Zia 
Published: January 2023

The first significant issue arising out of the COVID-19 pandemic for migrants who have been refused stay to come before the Administrative Court has been the question of the continued legality of immigration detention in the face of the risks and practical difficulties arising from the crisis. The pandemic raises two vital issues affecting the legality of immigration detention; on the one hand, that detainees may invite an increased risk of infection by reason of the “congregate” setting of detention centres, and on the other that removals in the short term will not be possible and that the probability of removal is uncertain even in the medium term. The issue is if the Home Office policy is “irrational and discriminatory” in its approach, which has led to inconsistencies in how the detention cases are handled. This paper enquires if the merit based judicial review can expedite the cases where administrative detention is concerned in circumstances of medical emergency. The argument here is that the Home Office should give full credence to the medical impact of detention to act in accordance with the Hardial Singh principles and by keeping in perspective the pandemic and the BMA reports of the unreasonableness of detention before deportation.
Message from the Guest Editor
Authors: Ilhan, Editor-in-Chief Prof. Dr. Ayse Cakir 
Published: January 2023

It is the great honor for me to edit this special issue of New Trends and Issues Proceedings on Humanities and Social Sciences for the selected revised papers presented in 9th WORLD CONFERENCE on DESIGN and ARTS (WCDA-2020) held on October 29-31, 2020, Athens, Greece. Art and Design in 21st century is being perceived with a different form and content with the developing technologies and changing needs. World Conference on Design and Arts welcomes a wide range of practical and theoretical approaches to discuss and develop new perspectives. The aim is to bring together the educational scientists, arts scientists, faculties, , designers, artists ,scholars, researchers and students from all areas of fine arts with the mission to become an International Forum, where, civil society organization and representative artists, academics and researchers – from all over the world – could meet in and exchange ideas to share and to discuss theoretical and practical knowledge about art and design in the scientific environment including Visual Performances, Graphic Designs Solutions Exhibitions, Workshops and Competitions. Furthermore, the journal is getting more international each year, which is an indicator that it is getting worldwide known and recognized. Scholars from all over the world contributed to this issue of the journal. Special thanks are to all the reviewers, the members of the international editorial board, the publisher, and those involved in technical processes. We would like to thank all who contributed to in every process to make this issue actualized. A total of 37 full papers and shorth papers or abstracts were submitted for this issue and each paper has been peer reviewed by the reviewers specialized in the related field. At the end of the review process, a total of 7 high quality research papers and 3 shorth papers were selected and accepted for publication.
I hope that you will enjoy reading the papers.
Best wishes...
Guest Editors
Prof. Dr. Ayşe Çakır İlhan
Ankara University, Turkey
Editorial Assistant
Daniel Sekyere-Asiedu, Near East University, North Cyprus
Message from the editor in chief
Authors: Laborda Jesus Garcia 
Published: January 2023

Dear reader,
It is with great pleasure that we present to you Volume 8, Issue 3 (2021) of the Selected Papers of 13th World Conference on Educational Sciences (WCES-2021), which took place between 04-06 February 2021, at the University of Cadi Ayyad, Marrakech, Morocco. This publication aims to present the selected topics on educational sciences, which reflect the current situation of education around the globe.
After a thorough review process, this publication selected topics from eight (8) countries including Iran, Malaysia, Saudi Arabia, Romania, Spain, Turkey, Kazakhstan, North Macedonia. The topics presented include Assessing teaching competency of academic staff at university level: Are we competent? ; Review study: Competency-based approach implementation in educational system; Identification and remediation of students’ disadvantages due to COVID-19; Explosive strength evolution of Romanian professional rugby players – Backs; Social phobia and addictive behaviours in adolescents; Application of repurposing in design education within the framework of sustainable design approach; Analysis of the last 10 years of articles and theses on authentic learning: A meta-analysis study; The effectiveness of educational structural factors and text design on students’ reading comprehension, among many other carefully selected topics.
We trust that the goal for this publication was realized and as such, we would like to thank all the contributors and the publishing team for their immense contribution to this publication.
Dear Reader, have a great time reading!!

Best Regards
Assoc. Prof. Dr. Jesus Garcia Laborda, University of Alcala, Spain
(Editor in chief)
EFEK PENGGUNAAN DOUBLE DAN SINGLE PISTON CALIPER TERHADAP WAKTU DAN JARAK TEMPUH PADA PENGEREMAN SEPEDA MOTOR 125 CC
Authors: Sopiyan  , Syaka Darwin Rio Budi , Muhammad Rafif Iqbal  
Published: January 2023

This study aims to determine the distance and braking time on 125cc motorcycle vehicles by using two types of callipers, namely single-piston and double-piston callipers. The research method uses experimental methods. There this method will compare 2 variables to get the results of the study by sulking on SNI Braking. By varying the two callipers of different types and using the brake pressure gauge, stopwatch, and meter to find out the pressure, time, and distance when conducting the test, the results of the test are calculated by the formula of regularly changing straight motion force (GLBB) slowed down, braking force and braking efficiency formula in order to get more valid results. Based on the results of this research report, it was concluded that the 2-piston callipers are superior to the 1-piston callipers in terms of average mileage of 0.51 m (9.81 m – 9.30 m) in front wheel braking and average mileage of 0.42 m (4.63 m – 4.21 m) in rear wheel braking and average stopping time of 0.21 s (2.51 s – 2.30 s) with the average effect of braking efficiency value of 5% (57% - 52 %) on front wheel braking and the average time for 0.21 s (1.58 s – 1.37 s) with the average effect of efficiency value of 5 % (47 % - 42 %) on rear wheel braking. So that makes 2-piston callipers better used in 125 cc vehicles than 1-piston callipers in terms of braking aspects.
Effect Of Proportion Of Flesh And Skin Of Bligo (Benincasa Hispida) On Bligo Pudding Characteristic
Authors: Mutaqqien Hexandria Abdullah , Nurbaya Syarifa Ramadhani , Saidi Ida Agustini , Budiandari Rahmah Utami 
Published: January 2023

Bligo plant (Benincasa hispida) is a plant that is still in the same family as the Cucurbitaceae plant. This study utilized the pulp and peel of the bligo fruit (Benincasa hispida) to make pudding using various proportions. The research design used a randomized block design (RBD) with 1 factor consisting of 6 treatment levels. Data were analyzed using Friedman test, ANOVA statistical analysis and 5% BNJ follow-up test. The best treatment was the concentration of the proportion of bligo meat and skin which showed in P3 treatment (bligo meat 60% bligo skin 40%) with a color organoleptic test value of 2.47 (normal-like), aroma organoleptic test of 2.20 (normal-like), organoleptic test texture organoleptic test 3.23 (normal-like), and taste organoleptic test 2.83 (normal-like).
Program MBKM Santri sebagai Pondasi Penguatan Nilai Religius di Era Society 5.0
Authors: Insani Erikafatul , Rozi Fathor , Asy’ari Hasyim 
Published: January 2023

Pesatnya revolusi industri teknologi dan moralisasi di Era Society 5.0 mengalami problematika yang kompleks. Sebagaimana perubahan segala bentuk budaya dan cara pandang individu berdampak pada dekadensi moral mahasiswa. Hal tersebut mendorong Universitas Nurul Jadid untuk ikut andil dalam Program MBKM Santri guna mempertahankan dan menjaga mahasiswanya untuk tetap dalam moralitas keagamaan. Tujuan penelitian ini untuk mengetahui apa saja program MBKM untuk mahasiswa berstatus santri sebagai pondasi penguatan nilai keagamaannya pada era 5.0. Penelitian ini menggunakan pendekatan kualitatif dengan jenis studi kasus di Universitas Nurul Jadid Paiton Probolinggo. Pengambilan data dilakukan melalui observasi dan wawancara berdasarkan kajian mendalam. Teknik analisis yang digunakan adalah teknik triangulasi data. Penelitian ini menunjukkan bahwa program MBKM sebagai upaya penguatan nilai keagamaan mahasiswa MBKM Santri pada era 5.0 melalui tiga program pokok yakni; 1) program pertukaran santri, 2) program santri mengabdi, serta 3) program santri mengajar. Program MBKM santri ini menciptakan mahasiswa-santri melatih dan menyalurkan soft skill dan hard skill sesuai minat dan bakatnya. Setiap mahasiswa-santri UNUJA dibekali dengan nilai Trilogi dan Pancakesadaran santri yang memudahkan mereka untuk terjun kepada kondisi sosial masyarakat yang berbeda. Memasuki era 5.0, maka program MBKM ini menjadi solutif bagi dunia pendidikan menanamkan soft skill dan hard skill siswa yang mampu menghadapi tantangan globalisasi.
Inovasi Teknologi Pembelajaran dengan Menggunakan Aplikasi Wordwall Website pada Mata Pelajaran PAI di Masa Penerapan Pembelajaran Jarak Jauh: Tinjauan Pustaka
Authors: Khoriyah Rifatul , Muhid Abdul 
Published: January 2023

Teknologi dan informasi yang berkembang pesat, mampu membawa dunia pendidikan bergerak kearah yang lebih maju, informasi dan komunikasi semakin mudah diakses terlebih dalam dunia pendidikan. Inovasi pembelajaran perlu dilakukan agar dapat mengembangkan dan memudahkan proses pembelajaran. sehingga pendidik dituntut untuk melakukan kreatifitas dengan memanfaatkan teknologi sebagai media yang akan menunjang keberhasilan tujuan pembelajaran. Pelajaran PAI merupakan pelajaran inti disetiap jenjang pendidikan, agar mampu menumbuhkan semangat dan menjadi pembelajaran yang menyenangkan maka seorang pendidik harus memanfaatkan kemajuan teknologi dan informasi salah satunya dengan memanfaatkan game edukasi berbasis website yang dikenal dengan wordwall. Wordwall dalah game edukatif dan interaktif yang sangat cocok untuk menciptakan pembelajaran yang menarik, karena fitur didalamnya memuat berbagai jenis game yang memudahkan peserta didik memahami materi pelajaran melalui gamifikasi. Metode penelitian ini adalah kualitatif dengan pendekatan kepustakaan sebagai sumber informasi dalam melakukan inovasi teknologi pembelajaran di masa penerapan pembelajaran jarak jauh. Metode analisis data dalam penelitian ini secara deskriptif, dengan tujuan mendeskripsikan dan menemukan bentuk inovasi pembelajaran yang dilakukan oleh pendidik. Media wordwall berisi game berbasis kuis seperti mencocokkan jawaban, menggolongkan jawaban, anagram, acak kata, pencarian kata, memasangkan pasangan jawaban, dsb. Melalui media wordwall website ini pendidik mampu berinovasi dalam melakukan pembelajaran pada mata pelajaran PAI di masa penerapan pembelajaran jarak jauh, hal ini terlihat dari adanya peningkatan pemahaman serta peningkatan hasil belajar yang signifikan terhadap mata pelajaran PAI.
Bacteriophage Liquid Propagation in Pseudomonas aeruginosa
Authors: Kunisch Fabian , Moreno Mercedes Gonzalez 
Published: January 2023

Abstract
This protocol provides a liquid production method for the propagation of bacteriophages (phages), wherein bacteria and phages are co-incubated in liquid medium under constant agitation. The advantages of this protocol are its easy use and the low costs, as there is no specialized equipment required. Besides the fact that not all phages can be propagated using a liquid approach, another disadvantage of this protocol is the strong dependence on the bacterial growth rate which will result in different protocol durations (e.g., 25:15 h for P. aeruginosa).
Bacteriophage DNA Organic Extraction
Authors: Kunisch Fabian , Wagemans Jeroen , Moreno Mercedes Gonzalez 
Published: January 2023

Abstract
This protocol is designed for the extraction of bacteriophage (phage) DNA used in downstream applications such as whole genome sequencing. For this purpose, the phage lysate is treated with DNase I and RNase A to degrade any DNA or RNA that is not enclosed by the viral capsid (e.g., from bacterial origin), and then EDTA and SDS are added to inactivate the DNase I/RNase A along with the addition of proteinase K to digest the viral capsid. Thereafter, protein debris are removed by sequential extraction with phenol-chloroform and precipitation with ethanol, which increases DNA concentration and removes excess salts. Compared to commercial kits, the price per sample is lower for this protocol, without entailing greater complexity or yielding inferior results.
Bacteriophage Precipitation with Polyethylene Glycol (PEG)
Authors: Kunisch Fabian , Wagemans Jeroen , Moreno Mercedes Gonzalez 
Published: January 2023

Abstract
This protocol can be employed to both purify and concentrate bacteriophages (phages) after their production. As a hygroscopic substance, polyethylene glycol in combination with its co-precipitant sodium chloride binds water molecules leading to the precipitation of the phages. After centrifugation, those can then be collected and resuspended in a buffer solution. While the purification with polyethylene glycol is a cost effective, fast (approx. 4:50 h) and easy to use method, it also has weaknesses related to the quality of purification, as both PEG and NaCl, as well as bacterial components, can contaminate the centrifuged phage precipitate.
Bioinformatics analysis of PDAC subtypes
Authors: Hyeon Do Young , Nam Dowoon , Han Youngmin , Kim Duk Ki , Kim Gibeom , Kim Daeun , Bae Jingi , Back Seunghoon , Mun Dong-Gi , Madar Inamul Hasan , Lee Hangyeore , Kim Su-Jin , Kim Hokeun , Hyun Sangyeop , Kim Chang Rok , Choi Seon Ah , Kim Yong Ryoul , Jeong Juhee , Jeon Suwan , Choo Yeon Woong , Lee Kyung Bun , Kwon Wooil , Choi Seunghyuk , Goo Taewan , Park Taesung , Suh Young-Ah , Kim Hongbeom , Ku Ja-Lok , Kim Min-Sik , Paek Eunok , Park Daechan , Jung Keehoon , Baek Sung Hee , Jang Jin-Young , Hwang Daehee , Lee Sang-Won 
Published: January 2023

Abstract
The associated publication reports proteogenomic analysis of human pancreatic ductal adenocarcinoma (PDAC), where we provided significantly mutated genes (SMGs)/biomarkers, cellular pathways, and cell types as potential therapeutic targets to improve stratification of patients with PDAC. This protocol describes the detailed methods for bioinformatics analysis of PDAC subtypes, including tumour purity estimation, subtype prediction for tumour samples in previous cohorts, pathway enrichment analysis, kinase activity analysis, and pan-omics analysis.
Pre- and post-genotype filtration protocol to improve the variant imputation metrics with further quality control
Authors: C Charon , R Allodji , V Meyer , JF Deleuze 
Published: January 2023

Abstract
The search for loci linked to diseases or drug targets is being studied by genotyping variants. Missing variants can be imputed, but the standard filtration methods applied during quality control(QC) reduced their number for downstream analyses.There is no standard protocol to retain the maximum of variants with reliable quality. To counteract this loss, we first limited the stringency of MAF SNP pre-filtration (MAF-DS), which improved post-imputation metrics with the 1000 Genomes (inc. INFO based on allele frequencies). Second, our two-step post-filtration strategy (1)computes a confident MAF threshold (MAF-DH), (2)filters with the quality score >0.3 and gains ~18% of reliable markers compared to conservative methods (single-step INFO>0.8) and confidence vs. non-conservative methods (single-step INFO>0.3).During the pre-and post-filtration steps, the MAF and allele accuracies were validated against a public database for further QC.The protocol is also applicable to any study since the metric MAFs are adapted to the sample set.
A Variegated GWO Algorithm Implementation in emerging power systems optimization problems
Authors: DEY BISHWAJIT , Raj Saurav , Mahapatra Sheila 
Published: January 2023

Abstract
This paper proposes a novel strong and robust hybrid algorithm which is mathematical modelled by amalgamating the superior features of recently developed grey wolf optimizer (GWO), sine cosine algorithm (SCA), and crow search algorithm (CSA). Researchers have already implemented the aforementioned three algorithms and obtained superior quality results for solving diverse optimization problems. The novel hybrid Variegated GWO Algorithm (VGWO) developed in this paper is initially realized for solving a long list of uni-cum-mutli modelled CEC-C06 2019 benchmark functions. Thereafter, proposed VGWO is utilized as optimization tool to solve three emerging power system optimization problems which include energy management of microgrid systems operating in both islanded and grid-connected mode, dynamic economic emission dispatch and reactive power planning of standard IEEE-57 bus test system. Numerical results show that the novel hybrid VGWO algorithm outperformed an ample number of optimization techniques in providing better quality solutions. The capability of handling many complex constraints within a minimum amount of computational time to provide consistently best solutions prioritize the proposed hybrid algorithm among its kinds. Statistical analysis validates the authenticity and viability of the proposed algorithm.
A modified genetic algorithm for combined heat and power economic dispatch
Authors: Li Deliang , Yang Chunyu , Zou Dexuan 
Published: January 2023

Abstract
Combined heat and power economic dispatch (CHPED) is an important issue in the energy field, since it has great potential in improving the utilization efficiency of power and heat energies. This paper proposes a modified genetic algorithm (MGA) to determine the power and heat outputs of three kinds of units for CHPED. First, MGA replaces the simulated binary crossover by a new one based on the uniform and guassian distributions, and its convergence can be enhanced. Second, MGA modifies the mutation operator by introducing a disturbance coefficient based on guassian distribution, which can decrease the risk of being trapped into local optima. Eight instances with or without prohibited operating zones are used to investigate the efficiencies of MGA and other four genetic algorithms for CHPED. MGA attains the smallest mean and standard deviation related to 50 cost values for every instance, thus it has desirable convergence and stability for CHPED in comparison with the other four genetic algorithms.