bluuebunny/crossref_metadata_2025_split huggingface dataset:
Implementation of substance use screening in rural federally-qualified health center clinics identified high rates of unhealthy alcohol and cannabis use among adult primary care patients
Authors: McNeely Jennifer , McLeman Bethany , Gardner Trip , Nesin Noah , Amarendran Vijay , Farkas Sarah , Wahle Aimee , Pitts Seth , Kline Margaret , King Jacquie , Rosa Carmen , Marsch Lisa , Rotrosen John , Hamilton Leah 
Published: September 2023

Abstract
Background
Screening for substance use in rural primary care clinics faces unique challenges due to limited resources, high patient volumes, and multiple demands on providers. To explore the potential for electronic health record (EHR)-integrated screening in this context, we conducted an implementation feasibility study with a rural federally-qualified health center (FQHC) in Maine. This was an ancillary study to a NIDA Clinical Trials Network study of screening in urban primary care clinics (CTN-0062).

Methods
Researchers worked with stakeholders from three FQHC clinics to define and implement their optimal screening approach. Clinics used the Tobacco, Alcohol, Prescription Medication, and Other Substance (TAPS) Tool, completed on tablet computers in the waiting room, and results were immediately recorded in the EHR. Adult patients presenting for annual preventive care visits, but not those with other visit types, were eligible for screening. Data were analyzed for the first 12 months following implementation at each clinic to assess screening rates and prevalence of reported unhealthy substance use, and documentation of counseling using an EHR-integrated clinical decision support tool, for patients screening positive for moderate-high risk alcohol or drug use.

Results
Screening was completed by 3749 patients, representing 93.4% of those with screening-eligible annual preventive care visits, and 18.5% of adult patients presenting for any type of primary care visit. Screening was self-administered in 92.9% of cases. The prevalence of moderate-high risk substance use detected on screening was 14.6% for tobacco, 30.4% for alcohol, 10.8% for cannabis, 0.3% for illicit drugs, and 0.6% for non-medical use of prescription drugs. Brief substance use counseling was documented for 17.4% of patients with any moderate-high risk alcohol or drug use.

Conclusions
Self-administered EHR-integrated screening was feasible to implement, and detected substantial alcohol, cannabis, and tobacco use in rural FQHC clinics. Counseling was documented for a minority of patients with moderate-high risk use, possibly indicating a need for better support of primary care providers in addressing substance use. There is potential to broaden the reach of screening by offering it at routine medical visits rather than restricting to annual preventive care visits, within these and other rural primary care clinics.
Systematic review of prospective studies assessing risk factors to predict anorexia nervosa onset
Authors: Charrat Jean-Philippe , Massoubre Catherine , Germain Natacha , Gay Aurélia , Galusca Bogdan 
Published: September 2023

Abstract
Background
According to case‒control studies, a multitude of factors contribute to the emergence of anorexia nervosa (AN). The present systematic review examines prospective studies specifically designed to evaluate the prediction of AN onset.

Methods
According to the ARMSTAR 2 and PRISMA 2020 checklists, the PubMed, PsycINFO and Cochrane databases were searched. The methodological quality of the studies was assessed with the Downs and Black checklist.

Results
Three articles concerning prospective studies of the general population were ultimately included in the review. The methodological quality of these studies was not optimal. Bidirectional amplification effects were observed between risk factors, some of which could have a relative predictive force as low bodyweight or body dissatisfaction. Even if not included according to specified criteria for this systematic review 11 longitudinal studies, with retrospective analysis of AN onset’ prediction, were also discussed. None of these studies asserted the predictive value of particular risk factors as low body weight, anxiety disorders or childhood aggression.

Conclusions
To date there are insufficient established data to propose predictive markers of AN onset for predictive actions in pre-adolescent or adolescent populations. Future work should further evaluate potential risk factors previously identified in case‒control/retrospective studies within larger prospective investigations in preadolescent populations. It is important to clearly distinguish predisposing factors from precipitating factors in subjects at risk of developing AN.
4-Mercaptobenzoic acid-modified Au@Ag nanoparticle-based colorimetric Cr3+ ions detection in aqueous solution
Authors: Zhang Zhikun , Li Heng , Guo Dongan , Hu Cuixia , Liu Yumin 
Published: September 2023

AbstractHeavy metal ions pose a threat to both ecological balance and human health owing to the non-biodegradable and poisonous characteristics. A simple, convenient and rapid metal ion monitoring plays a significant role for eliminating metal ions pollution. In this work, we prepared 4-mercaptobenzoic acids (4-MBA)-functionalized silver-coated gold nanoparticles (Au@Ag NPs) as colorimetric probes to construct colorimetric Chromium III (Cr3+) ions detection platform. The results showed that 4-MBA-Au@Ag NPs could effectively coordinate with the low-concentration Cr3+ ions with the group of -COOH, generating the obviously colorimetric reaction. To detection system, the optimal concentration of 4-MBA and pH was 5 μM and 9, respectively. Signal response was found to be proportional to Cr3+ ions concentration in the range from 10 to 500 μM with a correlation coefficient of 0.993, with UV–Vis and colorimetric detection limits determined as 9 μM and 10 μM, respectively. In addition, the recovery of the system was estimated to be from 88.2 to 112.1%, which was satisfactory for practical analysis of samples. The platform would have great potential applications in many areas.
It is time to target psychological readiness (or lack of readiness) in return to sports after Anterior Cruciate Ligament tears
Authors: Faleide Anne Gro Heyn , Inderhaug Eivind 
Published: September 2023

AbstractFunctional recovery has for long been the focus of rehabilitation after an Anterior Cruciate Ligament (ACL) injury. It is now increasingly recognized that more attention should be given to patients' mental recovery, their psychological readiness for returning to sport, after such an injury. Within this relatively new field of science, clinicians need clarity on when and how psychological factors should be monitored and how inexpedient psychological responses may be addressed during rehabilitation. In this Expert Opinion suggestions on how targeting psychological readiness may improve rehabilitation and return‐to‐sport evaluations are made based on current evidence—and issues in need of further clarification are addressed.
Comparing the Performance Gap Between Males and Females in the Older Age Groups in IRONMAN® 70.3: An Internet-Based Cross-Sectional Study of More Than 800,000 Race Records
Authors: Knechtle Beat , Valero David , Villiger Elias , Thuany Mabliny , Andrade Marilia Santos , Nikolaidis Pantelis T. , Cuk Ivan , Weiss Katja 
Published: September 2023

Abstract
Background
The sex difference in the three split disciplines (swimming, cycling, and running) and overall race times in triathlon races has mainly been investigated for the Olympic distance and IRONMAN® triathlon formats, but not for the half IRONMAN® distance, i.e., the IRONMAN® 70.3. The aim of the present study was to investigate the sex differences in IRONMAN® 70.3 by age group in 5-year intervals for the split disciplines of this race. Data from 823,459 records (625,393 males and 198,066 females) of all age group finishers (in 5-year intervals) competing in all official IRONMAN® 70.3 races held worldwide between 2004 and 2020 were analyzed, and sex differences by age group and split disciplines were evaluated.

Results
Males were faster than females in all split disciplines and all age groups. The sex difference was lower in swimming than in cycling and running and less pronounced for triathletes between 20 and 50 years of age. After the age of 60 years, females were able to reduce the sex difference to males in swimming and cycling, but not in running, where the reduction in the sex difference started after the age of 70 years. The lowest sex difference was in the age group 75 + years for swimming and cycling and in the age group 30–34 years for running. Across age groups, the sex difference was U-shaped in swimming and running, with an increase after 18–24 years in swimming and after 40–44 years in running. In contrast, the sex difference decreased continuously with the increasing age for cycling.

Conclusions
In conclusion, the study found that the sex difference in performance decreases with age in the IRONMAN® 70.3 race distance. However, females did not outperform males at older ages. Notably, sex differences were observed across different disciplines, with swimming displaying lower differences compared to cycling and running. These findings underscore the complex interplay between age, sex, and performance in endurance sports, emphasizing the need for additional research to understand the factors influencing these differences.
Bridges of perspectives: representation of people with lived experience of spinal cord injury in editorial boards and peer review
Authors: Nuechterlein Anna , Barretto Tanya , Yehia Alaa , Illes Judy 
Published: September 2023

Abstract
Background
Diversity among editorial boards and in the peer review process maximizes the likelihood that the dissemination of reported results is both relevant and respectful to readers and end users. Past studies have examined diversity among editorial board members and reviewers for factors such as gender, geographic location, and race, but limited research has explored the representation of people with disabilities. Here, we sought to understand the landscape of inclusivity of people with lived experience of spinal cord injury specifically in journals publishing papers (2012–2022) on their quality of life.

Methods
An open and closed 12-question adaptive survey was disseminated to 31 journal editors over a one-month period beginning December 2022.

Results
We received 10 fully completed and 5 partially completed survey responses (response rate 48%). Notwithstanding the small sample, over 50% (8/15) of respondents indicated that their journal review practices involve people with lived experience of spinal cord injury, signaling positive even if incomplete inclusivity practices. The most notable reported barriers to achieving this goal related to identifying and recruiting people with lived experience to serve in the review and editorial process.

Conclusions
In this study we found positive but incomplete trends toward inclusivity in journal practices involving people with lived experience of spinal cord injury. We recommend, therefore, that explicit and genuine efforts are directed toward recruitment through community-based channels. To improve representation even further, we suggest that editors and reviewers be offered the opportunity to self-identify as living with a disability without discrimination or bias.
The accuracy of whole-body 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) in the detection of ovarian cancer relapse in patients with rising cancer antigen 125 (CA-125) levels
Authors: Sami Soha , Hamed Soha Talaat , Adel Lamia , Kandeel Ahmed Abdel Samie , Kamal Eman Faker , Fakhry Sherihan 
Published: September 2023

Abstract
Background
18F-fluorodeoxyglucose (FDG) PET/CT is a noninvasive imaging tool that has been used successfully for the diagnosis, staging, restaging, therapy monitoring, and prognostic prediction of ovarian cancer. For ovarian cancer surveillance, rising CA-125 levels raise the suspicion of recurrence despite its reported low specificity; being elevated in other benign and inflammatory conditions, and thus, confirmation is required. This work aimed to evaluate the role of 18F-FDG PET/CT in suspected ovarian cancer recurrence in patients presenting with elevated CA-125 levels.

Results
Fifty female patients with suspected ovarian cancer recurrence owing to elevated CA-125 levels were included in this study. Recurrence was confirmed in 46/50 cases whether by histopathological confirmation or by serial follow-up imaging and clinical follow-up. Positive PET/CT findings were reported in 45/50 cases with 2 false-negative cases and 1 false-positive case. PET/CT examination was found to be superior to contrast-enhanced CT in the detection of peritoneal metastatic nodules and metastatic lymph nodes. According to this study, the estimated sensitivity, specificity, and overall diagnostic accuracy of PET/CT in the detection of recurrent ovarian cancer were 95.6%, 75%, and 94%, respectively.

Conclusions
In ovarian cancer surveillance, 18F-FDG PET/CT was found to be a sensitive and accurate noninvasive imaging tool that can be used in the detection of recurrent ovarian cancer in patients with elevated CA-125 levels, thus interfering with the management plan. The advantage of whole-body imaging in PET/CT allows for the detection and precise localization of recurrent or metastatic foci in abdominal and extra-abdominal sites as well.
Decolonizing US Comparative Literature: The 2022 ACLA Presidential Address
Authors: Shih Shu-mei 
Published: September 2023

AbstractThis essay examines how comparative literature as a discipline has never confronted its interlocking contexts of settler colonialism, imperialism, and racialization as its conditions of possibility in the United States. Inspired by recent efforts at decolonization in other disciplines, this essay calls for decolonizing comparative literature via a critique of the discipline from the nineteenth century to the present. From evolutionary scientism at its origin, overarching and continuing Eurocentrism, the disavowal of area studies, the rise of literary theory, and the primacy of non-US-focused postcolonial studies to problematic conceptions of multiculturalism, the discipline has scrupulously dissociated itself from the US reality. This dissociation, in the final analysis, replicates and supports the settler-colonial structure that evacuates the Indigenous peoples from their land and replaces Indigenous knowledge with settler knowledge, showing comparative literature to be a settler-colonial discipline. Hence, the necessary settler-colonial critique of comparative literature ought to be superseded by Indigeneity-centered practices in our work for decolonization to be possible.
Voicing the Malayan Emergency: Ventriloquizing Subjectivity in British Colonial Film and Radio
Authors: Bloom Peter J. 
Published: September 2023

Abstract
British colonial film and radio broadcasting initiatives are described as a foundational context for shaping the Malayan Emergency (1948–60). The development and deployment of counterinsurgency techniques become a means by which to wage war against what came to be identified as the Communist insurgency, previously trained and allied with Anglo-American forces against the Japanese occupation from 1942 to 1945. Key British figures associated with propaganda tactics during World War II, such as Hugh Carelton Greene, were instrumental in developing a new array of techniques for postwar propaganda. This article considers the extent to which film and radio programming were elemental to managing popular aspirations for independence just as economic and political authority became increasingly consolidated within the terms of Anglo-American economic and political interests. It considers how film and media programs contributed to the construction of the “Communist terrorist” by reference to several radio segments and films that were produced during this period. A significant part of the Malayan Emergency was associated with a large-scale population resettlement program known as the Briggs Plan. It was conceived as an effective population-centric strategy of political control that relied upon a biopolitics of security that became integral to Cold War political objectives. It is within the terms of a Cold War media complex that this discussion addresses the context for “radio-cinema governmentality.”
Can the “Comfort Women” Footage Speak? The Afterlives of Camera Images as Document and the Flow of Life
Authors: Kim Han Sang 
Published: September 2023

Abstract
When the US Army footage documenting the Korean victims of wartime sex slavery in the Imperial Japanese Army in China was discovered and released to the public in the summer of 2017, some South Korean academics questioned whether it should be understood as new evidence since it was believed that some of the subjects of the moving image had already been seen and located in photographs discovered previously in the 1990s. This reaction seemed diametrically opposed to that of the mainstream media (and social media), which excitedly praised the discovery of the “brand-new” evidential document depicting those moving women.
This article examines the politics of using film footage excavated from archives long after the original production of the film. Both types of reactions shown toward the “comfort women” footage shared the same attitude, which viewed the footage as a repository containing certain photographic-mechanical evidence to prove someone's existence in a scientific manner. Such a belief in the scientific nature of camera images bears a striking similarity with positivist historical approaches. Contrastingly, what Kracauer saw in film as a medium was rather the presence of things that are difficult to freeze and solidify. His concept of the “flow of life” describes an affinity with life (in the form of everyday life) that he theorized films possess but photographs do not. This article seeks a visual sociological method to explore film as a medium that embodies the reality of the subalterns and, if circumstances allow, speaks on their behalf.
Archiving Facts and Documentary Films: Sites of Memorial Struggle for the October 6, 1976, Massacre in Thailand
Authors: Musikawong Sudarat , Khumsupa Malinee 
Published: September 2023

Abstract
None of the perpetrators involved in the October 6, 1976, massacre in Thailand have been brought to justice. It has been this “culture of impunity” that limits the possibility of truth projects. Past state violence has been protected by the country's blanket amnesty laws and libel laws. Additionally, unreleased archival materials are restricted from public release by copyright law. Audiovisual and documentary evidence for counter-memory projects are thus challenged. On the other hand, evidence collected by activist archivist groups reveals painful memories from the relatives of victims and provides hope for truth-seeking. Collections of photographs, audio interviews, testimonies, and artifacts are utilized by both archivists and documentary filmmakers to forge claims toward restorative justice. And while the dominant discourse forces society at large to keep silent, historians, archivists, and filmmakers collectively resist forgetting. Together they lay claim to photographic and audio evidence as well as personal painful memories to illustrate and generate public dialogue, telling truths through sight and sound. Some of these archival efforts led to practices in participatory documentary-making. Collectively, these efforts in archival practice and filmmaking give birth to an ethic of immediation in humanitarianism. Thailand's next generation is engaged in recalling memories of past state violence and questioning the present authoritarian regime through archival filmmaking and exhibition practices.
Neurotropism of SARS-CoV-2: A Pathological Examination of Neurosurgical Specimens
Authors: Fujii Tatsuhiro , Rennert Robert C. , Hurth Kyle M. , Ward Pamela M. , Campan Mihaela , Mathew Anna J. , Dubeau Louis , Wallace William D. , Liu Charles Y. , Russin Jonathan J. 
Published: September 2023

BACKGROUND AND OBJECTIVES:
Neurological manifestations may occur in more than 80% of patients hospitalized with COVID-19 infection, including severe disruptions of the central nervous system (CNS), such as strokes, encephalitis, or seizures. Although the primary pathophysiological mechanism for the effects of COVID-19 in CNS remains unknown, evidence exists for both direct injury from neuroinvasion and indirect effects from disruptions in systemic inflammatory and coagulation pathways. In this study, we analyzed CNS tissue from living patients to better understand these processes.

METHODS:
With institutional review board approval and patient consent, samples that would be otherwise discarded from patients with active or recent (within 6 days of surgery) COVID-19 infection undergoing neurosurgical intervention were collected and tested for the presence of SARS-CoV-2 using immunohistochemistry, in situ hybridization, electron microscopy, and reverse transcription polymerase chain reaction.

RESULTS:
Five patients with perioperative mild-to-moderate COVID-19 infection met inclusion criteria (2 male, 3 female; mean age 38.8 ± 13.5 years). Neurosurgical diagnoses included a glioblastoma, a ruptured arteriovenous malformation, a ruptured posterior inferior cerebellar artery aneurysm, a middle cerebral artery occlusion, and a hemorrhagic pontine cavernous malformation. Samples analyzed included the frontal lobe cortex, olfactory nerve, arteriovenous malformation/temporal lobe parenchyma, middle cerebral artery, cerebellum, and cavernous malformation/brainstem parenchyma. Testing for the presence of SARS-CoV-2 was negative in all samples.

CONCLUSION:
The CNS is likely not a significant viral reservoir during mild-to-moderate COVID-19 infection, although direct neuroinvasion is not definitively excluded. Additional testing to help elucidate the relative contributions of direct and indirect pathways for CNS injury from COVID is warranted.
Identification of histone deacetylase inhibitors as neutrophil recruitment modulators in zebrafish using a chemical library screen
Authors: Fan Sijia , Jiang Jinlong , Zhang Huan , Wang Cuihong , Kong Shang , Zhao Tingting , Meng Ling , Liu Yang , Qin Jingjing , Rong Xiuqin , He Zhenting , He Qinke , He Ke , Chen Ketong , Lei Ling , Hai Xinyu , Nie Hong , Ren Chunguang 
Published: September 2023

ABSTRACT
Tissue injury-induced neutrophil recruitment is a prerequisite for the initiation and amplification of inflammatory responses. Although multiple proteases and enzymes involved in post-translational modification (PTM) of proteins regulate leukocyte recruitment, an unbiased functional screen of enzymes regulating inflammatory leukocyte recruitment has yet to be undertaken. Here, using a zebrafish tail fin amputation (TFA) model to screen a chemical library consisting of 295 compounds that target proteases and PTM enzymes, we identified multiple histone deacetylase (HDAC) inhibitors that modulate inflammatory neutrophil recruitment. AR-42, a pan-HDAC inhibitor, was shown to inhibit neutrophil recruitment in three different zebrafish sterile tissue injury models: a TFA model, a copper-induced neuromast damage and mechanical otic vesicle injury (MOVI) model, and a sterile murine peritonitis model. RNA sequencing analysis of AR-42-treated fish embryos revealed downregulation of neutrophil-associated cytokines/chemokines, and exogenous supplementation with recombinant human IL-1β and CXCL8 partially restored the defective neutrophil recruitment in AR-42-treated MOVI model fish embryos. We thus demonstrate that AR-42 non-cell-autonomously modulates neutrophil recruitment by suppressing transcriptional expression of cytokines/chemokines, thereby identifying AR-42 as a promising anti-inflammatory drug for treating sterile tissue injury-associated diseases.