bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perspectives from a publishing ethics and research integrity team for required improvements
Authors: Alam Sabina , Wilson Laura 
Published: July 2023

Abstract
It is imperative that all stakeholders within the research ecosystem take responsibility to improve research integrity and reliability of published research. Based on the unique experiences of a specialist publishing ethics and research integrity team within a major publisher, this article provides insights into the observed trends of misconduct and how those have evolved over time, and addresses key actions needed to improve the interface between researchers, funders, institutions and publishers to collectively improve research integrity on a global scale.
Preoperative tractography algorithm for safe resection of tumors located in the descending motor pathways zone
Authors: Ordonez-Rubiano Edgar G. , Johnson Jason M. , Abdalá-Vargas Nadin , Zorro Oscar F. , Marin-Munoz Jorge H. , Álvarez-Tobián Ricardo , Forlizzi Valeria , Rangel Carlos Castillo , Luzzi Sabino , Campero Alvaro , Patiño-Gómez Javier G. , Baldoncini Matias 
Published: July 2023

Background:
Diffusion tensor imaging (DTI) tractography facilitates maximal safe resection and optimizes planning to avoid injury during subcortical dissection along descending motor pathways (DMPs). We provide an affordable, safe, and timely algorithm for preoperative DTI motor reconstruction for gliomas adjacent to DMPs.

Methods:
Preoperative DTI reconstructions were extracted from a prospectively acquired registry of glioma resections adjacent to DMPs. The surgeries were performed over a 7-year period. Demographic, clinical, and radiographic data were extracted from patients’ electronic medical records.

Results:
Nineteen patients (12 male) underwent preoperative tractography between January 1, 2013, and May 31, 2020. The average age was 44.5 years (range, 19–81 years). A complete radiological resection was achieved in nine patients, a subtotal resection in five, a partial resection in three, and a biopsy in two. Histopathological diagnoses included 10 patients with high-grade glioma and nine with low-grade glioma. A total of 16 perirolandic locations (10 frontal and six frontoparietal) were recorded, as well as two in the insula and one in the basal ganglia. In 9 patients (47.3%), the lesion was in the dominant hemisphere. The median preoperative and postoperative Karnofsky Performance Scores were 78 and 80, respectively. Motor function was unchanged or improved over time in 15 cases (78.9%).

Conclusion:
This protocol of DTI reconstruction for glioma removal near the DMP shows good results in low-term neurological functional outcomes.
Corporate Governance and Capital Structure: Evidence from Europe
Authors: Ahmed Amanj Mohamed , Ali Muhammad Nawzad , Hágen István 
Published: July 2023

Purpose: The objective of this paper is to investigate the association between corporate governance and capital structure.

Theoretical framework: Since 1970, when the concept of corporate governance is introduced, the debate on whether it might affect capital structure have been ongoing. It is largely believed that in the real world, when effective cooperate governance adopted, strong capital structure can be achieved. Nonetheless, the experimental evidence reveals a variety of findings on such association.

Design/Methodology/Approach: Panel data was collected form annual reports of 42 non-financial listed firms on Frankfort and Oslo stock exchange over the period 2017-2021. Ordinary Least Square (OLS) regression model is utilized to estimate the connection between dependent and independent variables.

Findings: The finding shows that BS and AUCS are positively related with the capital structure and the result is significant. With respect to corporate governance, BM and BR with DTA have a negative and significant relationship. CEOC has positive but insignificant connection with DTA. Similarly, insignificant relationship between CEOT and DTA was observed. FS as a control variable has positive association with DTA, whereas the CR related DTA inversely. Despite the fact that, European firms mainly followed with a good corporate governance style if compared with developing countries, the results are still recommended further improvement for the firms in both countries in order to improve the financial position

Research, practical & social implications: Future studies should focus on other corporate governance indicators that might affect capital structure significantly. It is also recommended for them to focus on financial firms and make a comparison between financial and non-financial firms.

Originality/Value: By providing significant data for the impact of corporate governance on capital structure, this research contributes with existing literature on governance mechanism and management of capital structure. The findings will guide policymakers in various countries in determining the effectiveness of availability corporate governance reforms to enhance the structure of capital.
Kick tolerance control during well drilling in southern Iraqi deep wells
Authors: Al-a'ameri Nagham Jasim 
Published: July 2023

The importance of kick tolerance in well operations has recently increased due to its implications in well design, in drilling and well control. To study a simple method for the application of kick tolerance concept in an effective way on the basis of field data, this research purpose is to improve knowledge about Kick Tolerance and represents a technical basis for the discussion on revision of standard procedure.
The objective of this work is to review and to present a methodology of determination the kick tolerance parameters using the circulation kicks tolerance concepts.
The proposed method allows to know, to evaluate and to analyze the kick tolerance problem in order to make the drilling execution safer and more economical by reducing the probability to have an incident.
The calculations of presented methodologies were based upon calculated input values such as ppore and pfrac. and not upon measured leak-off test and RFT (less accurate) input values as in traditional methods. The paper also analyses the calculations not with KT parameters only, but it has continued to give the killing operation procedure to such high pressure high temperature (HPHT) wells.
Permeability Prediction in One of Iraqi Carbonate Reservoir Using Hydraulic Flow Units and Neural Networks
Authors: Alobaidi Dahlia Abdulhadi 
Published: July 2023

Permeability determination in Carbonate reservoir is a complex problem, due to their capability to be tight and heterogeneous, also core samples are usually only available for few wells therefore predicting permeability with low cost and reliable accuracy is an important issue, for this reason permeability predictive models become very desirable.
This paper will try to develop the permeability predictive model for one of Iraqi carbonate reservoir from core and well log data using the principle of Hydraulic Flow Units (HFUs). HFU is a function of Flow Zone Indicator (FZI) which is a good parameter to determine (HFUs).
Histogram analysis, probability analysis and Log-Log plot of Reservoir Quality Index (RQI) versus normalized porosity (øz) are presented to identify optimal hydraulic flow units. Four HFUs were distinguished in this study area with good correlation coefficient for each HFU (R2=0.99), therefore permeability can be predicted from porosity accurately if rock type is known.
Conventional core analysis and well log data were obtained in well 1 and 2 in one of carbonate Iraqi oil field. The relationship between core and well log data was determined by Artificial Neural Network (ANN) in cored wells to develop the predictive model and then was used to develop the flow units prediction to un-cored wells. Finally permeability can be calculated in each HFU using effective porosity and mean FZI in these HFUs. Validation of the models evaluated in a separate cored well (Blind-Test) which exists in the same formation. The results showed that permeability prediction from ANN and HFU matched well with the measured permeability from core data with R2 =0.94 and ARE= 1.04%.
Genome-wide association study of drought tolerance traits in sugar beet germplasms at the seedling stage
Authors: Li Wangsheng , Lin Ming , Li Jiajia , Liu Dali , Tan Wenbo , Yin Xilong , Zhai Yan , Zhou Yuanhang , Xing Wang 
Published: July 2023

Introduction: Sugar beets are an important crop for global sugar production. Intense drought and the increasing lack of water resources pose a great threat to sugar beet cultivation. It is a priority to investigate favourable germplasms and functional genes to improve the breeding of drought tolerant plants.Methods: Thus, in this study, 328 sugar beet germplasms were used in a genome-wide association study (GWAS) to identify single nucleotide polymorphism (SNP) markers and candidate genes associated with drought tolerance.Results: The results showed that under drought stress (9% PEG-6000), there were 11 significantly associated loci on chromosomes 2, 3, 5, 7, and 9 from the 108946 SNPs filtered using a mixed linear model (MLM). Genome-wide association analysis combined with qRT-PCR identified 13 genes that were significantly differentially expressed in drought-tolerant extreme materials.Discussion: These candidate genes mainly exhibited functions such as regulating sugar metabolism, maintaining internal environmental stability and participating in photosystem repair. This study provides valuable information for exploring the molecular mechanisms of drought tolerance and improvement in sugar beet.
Evaluation of humoral immune response in relation to COVID-19 severity over 1 year post-infection: critical cases higher humoral immune response than mild cases
Authors: Bang Mi-Seon , Kim Choon-Mee , Cho Nam-Hyuk , Seo Jun-Won , Kim Da Young , Yun Na Ra , Kim Dong-Min 
Published: July 2023

IntroductionCoronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2. We investigated the antibody response against SARS-CoV-2 until 1 year after symptom onset.MethodsWe collected 314 serum samples from 97 patients with COVID-19. Antibody responses were tested using an indirect immunofluorescence assay (IFA), enzyme-linked immunosorbent assay (ELISA), and plaque reduction neutralization test (PRNT) to detect specific neutralizing antibodies.ResultsThe positivity rates for neutralizing antibodies at a 1:10 titer cutoff were 58.1% at 1 week, 97.8% at 4 weeks, and 78% at 1 year after symptom onset (53.8% in asymptomatic patients and 89.3% in symptomatic patients). The IFA and anti-S1 ELISA IgG results significantly correlated with neutralizing antibody titers. Critical/fatal cases showed significantly higher antibody titers than the asymptomatic or mild-to-moderate illness groups. Nonetheless, the median number of days to the seroconversion of neutralizing antibodies was 10 and 15 in asymptomatic and symptomatic patients, respectively. The asymptomatic group had a significantly higher neutralizing potency index than the mild-to-severe illness groups.ConclusionsNeutralizing antibodies corresponded to earlier seroconversion but had a shorter presence in the asymptomatic group than in the symptomatic group and were still present 1 year after symptom onset in critical/fatal cases.
Genus-wide genomic characterization of Macrococcus: insights into evolution, population structure, and functional potential
Authors: Carroll Laura M. , Pierneef Rian , Mafuna Thendo , Magwedere Kudakwashe , Matle Itumeleng 
Published: July 2023

IntroductionMacrococcus species have been isolated from a range of mammals and mammal-derived food products. While they are largely considered to be animal commensals, Macrococcus spp. can be opportunistic pathogens in both veterinary and human clinical settings. This study aimed to provide insight into the evolution, population structure, and functional potential of the Macrococcus genus, with an emphasis on antimicrobial resistance (AMR) and virulence potential.MethodsAll high-quality, publicly available Macrococcus genomes (n = 104, accessed 27 August 2022), plus six South African genomes sequenced here (two strains from bovine clinical mastitis cases and four strains from beef products), underwent taxonomic assignment (using four different approaches), AMR determinant detection (via AMRFinderPlus), and virulence factor detection (using DIAMOND and the core Virulence Factor Database).ResultsOverall, the 110 Macrococcus genomes were of animal commensal, veterinary clinical, food-associated (including food spoilage), and environmental origins; five genomes (4.5%) originated from human clinical cases. Notably, none of the taxonomic assignment methods produced identical results, highlighting the potential for Macrococcus species misidentifications. The most common predicted antimicrobial classes associated with AMR determinants identified across Macrococcus included macrolides, beta-lactams, and aminoglycosides (n = 81, 61, and 44 of 110 genomes; 73.6, 55.5, and 40.0%, respectively). Genes showing homology to Staphylococcus aureus exoenzyme aureolysin were detected across multiple species (using 90% coverage, n = 40 and 77 genomes harboring aureolysin-like genes at 60 and 40% amino acid [AA] identity, respectively). S. aureus Panton-Valentine leucocidin toxin-associated lukF-PV and lukS-PV homologs were identified in eight M. canis genomes (≥40% AA identity, &gt;85% coverage). Using a method that delineates populations using recent gene flow (PopCOGenT), two species (M. caseolyticus and M. armenti) were composed of multiple within-species populations. Notably, M. armenti was partitioned into two populations, which differed in functional potential (e.g., one harbored beta-lactamase family, type II toxin-antitoxin system, and stress response proteins, while the other possessed a Type VII secretion system; PopCOGenT p &lt; 0.05).DiscussionOverall, this study leverages all publicly available Macrococcus genomes in addition to newly sequenced genomes from South Africa to identify genomic elements associated with AMR or virulence potential, which can be queried in future experiments.
Connectome-based predictive modeling of smoking severity using individualized structural covariance network in smokers
Authors: Wang Weijian , Kang Yimeng , Niu Xiaoyu , Zhang Zanxia , Li Shujian , Gao Xinyu , Zhang Mengzhe , Cheng Jingliang , Zhang Yong 
Published: July 2023

IntroductionAbnormal interactions among distributed brain systems are implicated in the mechanisms of nicotine addiction. However, the relationship between the structural covariance network, a measure of brain connectivity, and smoking severity remains unclear. To fill this gap, this study aimed to investigate the relationship between structural covariance network and smoking severity in smokers.MethodsA total of 101 male smokers and 51 male non-smokers were recruited, and they underwent a T1-weighted anatomical image scan. First, an individualized structural covariance network was derived via a jackknife-bias estimation procedure for each participant. Then, a data-driven machine learning method called connectome-based predictive modeling (CPM) was conducted to infer smoking severity measured with Fagerström Test for Nicotine Dependence (FTND) scores using an individualized structural covariance network. The performance of CPM was evaluated using the leave-one-out cross-validation and a permutation testing.ResultsAs a result, CPM identified the smoking severity-related structural covariance network, as indicated by a significant correlation between predicted and actual FTND scores (r = 0.23, permutation p = 0.020). Identified networks comprised of edges mainly located between the subcortical–cerebellum network and networks including the frontoparietal default model and motor and visual networks.DiscussionThese results identified smoking severity-related structural covariance networks and provided a new insight into the neural underpinnings of smoking severity.
“Time wasted by health professionals is time not invested in patients”: time management practice and associated factors among health professionals at public hospitals in Bahir Dar, Ethiopia: a multicenter mixed method study
Authors: Addis Berihun Alemayehu , Gelaw Yared Mulu , Eyowas Fantu Abebe , Bogale Tewodros Worku , Aynalem Zewdu Bishaw , Guadie Habtamu Alganeh 
Published: July 2023

BackgroundTime management is of utmost importance in healthcare facilities since time squandered by health professionals is time not invested in patients, and this affects the quality of care given to patients. This study aimed to assess time management practice and factors affecting it among health professionals at public hospitals in Bahir Dar, Ethiopia.MethodsInstitution-based cross-sectional study supplemented with a qualitative study was conducted from April 21 to May 20, 2022, among health professionals working in public hospitals in Bahir Dar, Ethiopia. A simple random sampling technique was used to select 416 study participants. A pretested self-administered questionnaire was used to collect quantitative data, and an interviewer guide was used to collect qualitative data to complement quantitative data. Purposive sampling was used in the qualitative study, and 12 in-depth interviews were carried out till saturation was reached. The quantitative data were entered into Epi Data version 4.0 and analyzed using SPSS 25.0 whereas the qualitative data were analyzed manually using thematic analysis. To identify the associated factors, bi-variable and multivariable logistic regression analyses were used. The degree of associations was interpreted using odds ratio and 95% confidence interval at &lt;0.05 p-value.ResultsOf 416 invited participants, 410 of them participated in the study yielding a 98.5% response rate. The magnitude of time management practice among health professionals was 66.1% (95% CI: 61.5–70%). Age ranges 25–29 (AOR = 3.961, 95% CI: 1.068, 14.682) and 30–34 (AOR = 6.240, 95% CI: 1.640, 23.749), planning (AOR = 6.032, 95% CI: 3.478, 10.463), compensation and benefits packages (AOR = 1.888, 95% CI: 1.077, 3.309), responsible to work (AOR = 2.119, 95% CI: 1.192, 3.768), time waster (AOR = 1.855, 95% CI: 1.058, 3.251) and staff shortage (AOR = 0.535, 95% CI: 0.319, 0.896) were factors associated with time management practice. From the qualitative study, two major themes and five categories have emerged.Conclusion and recommendationsHealthcare facilities could improve their time management practices by providing training on planning, being a low time-waster and highly responsible at work, and designing compensation and benefits packages.
The experiences of remote consulting for people with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and fibromyalgia in primary care
Authors: Leach Helen , Atherton Helen , Eccles Abi , Chew-Graham Carolyn 
Published: July 2023

BackgroundRestrictions due to the COVID-19 pandemic resulted in a sudden shift to a predominantly remote consulting model in primary care from March 2020. Little evidence exists examining the experience of remote consulting for people living with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) or fibromyalgia, with the current literature focusing on the challenges faced by clinicians and people living with these conditions. Clinical guidance highlights the importance of building therapeutic relationships and personalising care, but it is unclear how this translates into a remote or virtual consulting space.AimTo explore how people living with CFS/ME and fibromyalgia experience remote consulting with a primary care clinician, including synchronous and asynchronous methods, that is, e-consultation platforms, email, video, and telephone.MethodSemi-structured interviews are being recorded and analysed thematically using a Foucauldian theoretical framework. Participants have been recruited across the West Midlands from a range of backgrounds.ResultsRecruitment is still ongoing. Preliminary analysis indicates that remote consulting is acceptable for these groups of patients, but only if they feel validated, listened to, and with a clinician who considers a holistic view with continuity of care.ConclusionRemote consulting has presented new challenges for primary care, and it is important to identify which groups of patients are most suited. This study explores the views from a group of patients that are associated with some complexity, and complements the literature that explores the ability to deliver relationship-based care when consulting digitally/remotely. Recommendations from the findings will be created for use by patients and clinicians alike.
Association of COVID-19 with short- and long-term risk of cardiovascular disease and mortality: a prospective cohort in UK Biobank
Authors: Wan Eric Yuk Fai , Mathur Sukriti , Zhang Ran , Yan Vincent Ka Chun , Lai Francisco , Chui Celine , Li Xue , Wong Carlos King Ho , Yiu Kai Hang , Chan Esther Wai Yin , Wong Ian 
Published: July 2023

BackgroundThe evidence on the short- and long-term associations of COVID-19 with cardiovascular disease (CVD) outcomes and mortality is limited.AimThis study aimed to evaluate these associations.MethodCOVID-19 patients (cases) diagnosed between 16 March 2020 and 30 November 2020 were identified from UK Biobank and followed prospectively for up to 18 months. Based on age and sex, cases were randomly matched with uninfected participants from two control cohorts — a contemporary cohort between 16 March 2020 and 30 November 2020, and a historical cohort between 16 March 2018 and 30 November 2018. Characteristics between groups were adjusted with propensity score-based marginal mean-weighting through stratification. The association of COVID-19 with CVD and mortality within 21 days of diagnosis (acute phase) and after this period (post-acute phase) was determined by Cox regression.ResultsIn the acute phase, patients with COVID-19 (n= 7584) were associated with a significantly higher risk of CVD (hazard ratio [HR] 4.3 [95% confidence interval (CI) = 2.6 to 6.9]); 5.0 (95% CI = 3.0 to 8.1)] and all-cause mortality (HR 81.1 [95% CI = 58.5 to 112.4); 67.5 [95% CI = 49.9 to 91.1]) than the contemporary (n= 75 790) and historical controls (n= 75 774), respectively. In the post-acute phase, infected patients’ (n= 7139) association with higher risk of CVD (HR 1.4 [95% CI = 1.2 to 1.8]; 1.3 [95% CI = 1.1 to 1.6]) and all-cause mortality (HR 5.0 [95% CI = 4.3 to 5.8); 4.5 (95% CI = 3.9 to 5.2]) persisted, compared with the contemporary (n= 71 296) and historical controls (n= 71 314), respectively.ConclusionCOVID-19 is associated with increased short- and long-term risks of CVD and mortality. Ongoing monitoring of signs and symptoms of developing cardiovascular complications post-diagnosis and up till at least a year post-recovery may benefit infected patients, especially those with severe disease.
Fresques murales durant la révolution libanaise de 2019 : des graffs, mémorial d’une nation réunie
Authors: Calargé Fady , Badr Maha 
Published: July 2023

Depuis le soulèvement de 2019, les fresques murales se sont multipliées au Liban et s’engagent dans la vie des citoyens pour exprimer leurs soucis, leur colère et leurs revendications. Il semble que, de par ses formes artistiques notamment murales, le « street art » constitue un élément incontournable pour refléter les valeurs de la « révolution ». Dans cet article, nous proposons de revenir, trois ans plus tard, sur le contexte libanais pour voir ce qui reste de ces créations artistiques et pour examiner leur impact sur la mémoire sociale du peuple. Notre hypothèse est que ces fresques et graffs ont pu transcender l’espace (les frontières régionales et géographies du Liban et dans les pays de la diaspora) et le temps (perçu comme moment phare dans lequel se contextualise le soulèvement populaire au Liban en 2019) pour établir une certaine ré-union de la communauté libanaise. Dans cette perspective, il nous incombe d’assumer deux responsabilités : la première c’est d’inventorier et de préserver ces créations artistiques ; la deuxième serait de les intégrer dans les programmes universitaires pour enseigner l’histoire récente du Liban.