bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of Factors Influencing Plant Diversity in Urban Wetlands Based on Structural Equation Model
Authors: Wang Yue , Yang Guofu , Wei Biao , Zhang Youli , Lu Yijun 
Published: September 2023

Abstract
Urban wetlands play a vital role within the urban ecosystem, and the application of ecological design methods in urban wetland planning and design can significantly enhance their biodiversity and improve the overall service functions of urban ecosystems. This study focuses on three urban wetlands: Xixi Wetland in the core area, Tongjian Lake Wetland in the fringe area, and Qingshan Lake Wetland in the suburban area. Meanwhile, four design factors of water quality protection, shoreline maintenance, ecological facilities, and plant diversity were investigated, together with 34 ecological design methods, based on statistics of the plant species composition of urban wetlands. Using structural equation modeling to screen out the design methods and influence paths that have an appreciable impact on plant diversity. We found variations in the three urban wetlands' plant compositions and ecological design strategies: (1) 336 species of plants were recorded in Xixi Wetland, 179 in Qingshan Lake Wetland, and 112 in Tongjian Lake Wetland; (2) the number of ecological design methods applied in Xixi Wetland is significantly higher than that of Tongjian Lake Wetland and Qingshan Lake Wetland; (3) ten ecological design methods in Qingshan Lake wetland significantly affected plant diversity, while five ecological design methods in both Xixi Wetland and Tongjian Lake wetland significantly affected plant diversity; (4) among all the ecological design methods, four-ecological conservation measures, rain gardens, plant community structure, and the use of different plant species-clearly impact wetland plant diversity. To ensure the protection, differential utilization, and sustainable development of urban wetlands in the context of urbanization, managers and designers should carefully select appropriate ecological design methods based on the specific characteristics of each urban wetland.
Effect of genotype on cadmium and trace element accumulation in wheat from weakly alkaline cadmium-contaminated soil
Authors: Ma Wenyan , Li YuLiang , Ge Chenghao , Mu Chunyi , Wang Min , Cheng Cheng , Zhou Dong-Mei 
Published: September 2023

Abstract

Cadmium (Cd) contamination of farmland soils leads to an increase in Cd accumulation and a decrease in the uptake of micronutrients by crops, posing grave risks to food safety. Herein, we investigated the enrichment and transportation patterns of Cd and trace elements in different parts of six wheat genotypes grown in weakly alkaline Cd-contaminated soils via pot experiments. Additionally, we delved into the connections between trace elements and Cd accumulation in wheat. The results revealed notable variations in the uptake of Cd in wheat grains based on genotype. The wheat grain variety with high Cd accumulation (Ningmai13) demonstrated a 1.94-fold increase compared to the variety with low accumulation (Yanong0428). The enrichment factor of Cd in wheat followed the order: root > stem > grain. Furthermore, the transfer of Cd from wheat straw to grain ranged from 0.319 to 0.761, while the transfer factor of Cd from root to straw ranged from 0.167 to 0.461. Regarding other metals, the concentrations of Zn, Mn, Cu, and Fe in wheat grains ranged as follows: 42 − 88 mg·kg-1, 27 − 49 mg·kg-1, 4 − 8 mg·kg-1, and 23 − 56 mg·kg-1, respectively. There was a significant positive correlation (p < 0.05) between Cd and Mn in wheat grains, indicating a potential synergistic effect that requires further investigation. However, no significant positive correlation was observed between Cd and Cu or Fe. Overall, this study provides valuable insights into the regulation of micronutrient intake to modulate Cd uptake in wheat, laying the foundation for further research in this area.
CLS, PLS and PCR Methods in Different Sets of Data for Simultaneous Determination of Paracetamol and Orphenadrine Citrate in Their Combined Pharmaceutical Dosage Forms
Authors: El-Adl Sobhy M. , Mattar Amr A. , Sebaiy Mahmoud M. , Fawzy Michael G. 
Published: September 2023

Abstract
The authors have requested that this preprint be removed from Research Square.
Pervasive cloud computing of Individualized recommendation method of characteristic service of education in post-epidemic era
Authors: Xin Wang , Dayong Liu 
Published: September 2023

Abstract
Individualized recommendation of political education characteristic services in post-epidemic era is to recommend suitable political education characteristic services to students through evaluation and judgment of students' learning interests and specialties. Therefore, this paper puts forward the Individualized recommendation method of political education characteristic services in post-epidemic era. Firstly, taking the information management platform as the structural model, this paper constructs students' scoring model and data homomorphic distribution attribute model for political education characteristic services. Using the method of analyzing the distribution characteristics of teaching resources to build a Individualized recommendation model, allocate personalized features and extract fitness parameters, so as to realize the individualized recommendation of political education characteristic services in post-epidemic era. The simulation results show that this method improves the score of recommended items and reduces the average absolute error and root mean square error of the score of recommended items. It improves the quality of dynamic and accurate matching of political education characteristic services and personalized differences in post-epidemic era.
Correlation of procalcitonin and c-reactive protein levels with pathogen distribution and infection localization in urinary tract infections
Authors: Shi Jing , Zhan Zhi-Song , Zheng Su-Shun , Zhu Xue-Xia , Zhou Xin-Yi , Zhang Shi-Yan 
Published: September 2023

Abstract
Aimed to explore the relationships between infection localization, bacterial species, and procalcitonin (PCT) and C-reactive protein (CRP) levels in urinary tract infections (UTIs). A retrospective study included 314 UTI hospitalized patients divided into two groups (268 with lower UTI, 46 with upper UTI) in a tertiary care hospital. PCT and CRP were performed. Bacterial isolates were identified using standard microbiological techniques, and statistical analyses were performed to assess associations between infection localization, bacterial species, PCT and CRP levels. Age and gender showed no significant differences between the lower and upper UTIs. Escherichia coli dominated as the leading UTI pathogen. A positive correlation (r = 0.646, P < 0.001) between PCT and CRP levels was found. The subgroup with ureteritis in the upper UTI category exhibited the highest PCT and CRP levels. PCT and CRP exhibited favorable diagnostic potential in predicting upper UTIs, with AUCs of 0.644 and 0.629, respectively. The optimal cutoff values were 0.21 ng/mL for PCT and 60.77 mg/L for CRP. Sensitivities were 69.03% and 77.99%, while specificities were 56.52% and 47.83%, respectively. E. coli emerged as the predominant bacterium in UTIs. PCT and CRP demonstrated moderate diagnostic efficacy in distinguishing between upper and lower UTIs. Notably, PCT and CRP exhibited enhanced utility in identifying ureteritis.
Impacts to Australian physiotherapy research during the COVID-19 pandemic – a scoping review
Authors: Trojman Anthony , Paratz Jennifer , Boots Robert , Hides Julie , Hough Judith , Aitchison Alex , Gustafsson Louise 
Published: September 2023

Abstract
Background
Australia’s strict lockdown measures posed significant logistical and practical challenges for researchers. The extent of the pandemic’s impact on physiotherapy research in Australia unknown. The aim of this scoping review was to identify how physiotherapy research conducted in Australia was impacted by the COVID-19 pandemic.
Methods
A scoping review was conducted in CINAHL, MEDLINE, PsychInfo (Ovid), Nursing & Allied Health via ProQuest, PubMed, and PEDro to identify Australian physiotherapy research conducted between March 2020 and January 2023 that reported the COVID-19 pandemic impacted their research.
Results
Thirty-five studies met the inclusion criteria. Four themes emerged regarding the pandemic's impact: delayed research (n = 8), reduced quality (n = 23), changed methods (n = 10), and cessation of research (n = 3). Ten studies reported more than one impact. Twenty-five studies used face-to-face methods and 10 used online/non-contact methods. Nine studies switched from face-to-face to online/non-contact methods. These nine studies reported less impacts relating to quality and/or delays.
Conclusion
Research conducted during the COVID-19 pandemic that used non-contact/online methods were less affected. To circumvent pandemic-related impacts, researchers may benefit from utilizing re-creative strategies when planning research by adopting principles of project management to develop more flexible research protocols.
Boosting all-weather atmospheric vapor harvesting with membrane distillation system powered by solar energy
Authors: Jin Yong , Ghaffour Noreddine 
Published: September 2023

Abstract
Atmospheric vapor harvesting represents an important freshwater supply. Sorbent-based atmospheric vapor harvesting stands out because it can adapt to various weather conditions and can utilize low-grade energy. Current sorbent-based atmospheric vapor harvesting research focuses on the preparation of sorbent materials (especially solid sorbents, e.g., MOFs) without integrating them into an advanced water production system. Moreover, solid sorbents are faced with poor adaptivity to changing relative humidity in real applications. To address the issues, we proposed a novel atmospheric vapor harvesting membrane distillation system (AVH-MD) that can boost water production and adapt to all-weather conditions simultaneously. The feasibility of the system was demonstrated by both theoretical and experimental tools. The system could produce 6.27, 2.41, and 0.82 kg freshwater/m2/day at relative humidities of 69%, 35%, and 19% at 25 OC, respectively. The production improved by almost 700% compared with the reported studies under the same condition. The converted water production capacity (kg/J) in our system is also the highest under various relative humidities compared with the reported studies.
African bush pigs exhibit porous species boundaries and appeared in Madagascar concurrently with human arrival
Authors: Heller Rasmus , Balboa Renzo , Bertola Laura , Brüniche-Olse Anna , Rasmussen Malthe Sebro , Liu Xiaodong , Besnard Guillaume , Salmona Jordi , Santander Cindy , He Shixu , Zinner Dietmar , Pedrono Miguel , Muwanika Vincent , Masembe Charles , Schubert Mikkel , Kuja Josiah , Quinn Liam , Garcia-Erill Genís , Rakotoarivony Rianja , Henrique Margarida , Lin Long , Wang Xi , Heaton Michael , Smith Timothy , Hanghøj Kristian , Sinding Mikkel-Holger , Atickem Anagaw , chikhi Lounès , Roos Christian , Gaubert Philippe , Siegismund Hans , Moltke Ida , Albrechtsen Anders 
Published: September 2023

Abstract
Several African mammals exhibit a phylogeographic pattern where closely related taxa are split between West/Central and East/Southern Africa, but their evolutionary relationships and histories remain controversial. Bushpigs (Potamochoerus larvatus) and red river hogs (P. porcus) are recognised as separate species due to morphological distinctions, a perceived lack of interbreeding at contact, and putatively old divergence times, but historically, they were considered conspecific. Moreover, the presence of Malagasy bushpigs as the sole large terrestrial mammal shared with the African mainland raises intriguing questions about its origin and arrival in Madagascar. Analyses of 67 whole genomes revealed a genetic continuum between the two species, with putative signatures of historical gene flow, variable FST values, and a recent divergence time (<500,000 years). Thus, our study challenges key arguments for splitting Potamochoerus into two species and suggests their speciation might be incomplete. Our findings also indicate that Malagasy bushpigs diverged from southern African populations and underwent a limited bottleneck 1,000-5,000 years ago, concurrent with human arrival in Madagascar. These results shed new light on the evolutionary history of an iconic and widespread African genus and provide insight into the longstanding biogeographic puzzle surrounding the bushpig's presence in Madagascar.
Carrier lifetime modulation on current capability of SiC PiN diodes in a pulsed system
Authors: Xu Xingliang , Zhang Lin , Li lianghui , Li Zhiqiang , Li Juntao , Zhang Jian , Dong Peng 
Published: September 2023

Abstract
Silicon carbide (SiC) PiN diode has shown substantial promise as the freewheel diode for switch protection in a pulsed system. In this paper, we investigate the carrier lifetime (τHL) modulation on pulsed current capability of SiC PiN diodes. The carrier lifetime in 4H-SiC is modulated by the generation of the Z1/2 center through neutron irradiation. Surprisingly, we found that the pulsed current of SiC PiN diodes shows limited improvement when the carrier lifetime (τ) increases from 0.22 ms to 1.3 ms, while is signiﬁcantly promoted as the carrier lifetime increases from 0.03 ms to 0.22 ms. This changing trend is obviously different from the on-state resistance, which monotonously decreases with the increased carrier lifetime. The simulation result proves that the heat generation (i.e. maximum temperature rise) inside the PiN diodes, especially in the drift layer, is remarkably aggravated in the pulse tests for τ < 0.1 ms, while is significantly suppressed as carrier lifetime rises to 0.2 ms and above. Therefore, the dependence of pulsed current on carrier lifetime is ascribed to the heat generation resulting from the carrier lifetime controlled conductivity modulation effect, which hence affects the temperature rise and therefore the failure of SiC PiN diodes under high pulsed current.
Characteristics of Vaginal Microbiota in various Cervical Intraepithelial Neoplasia: A Cross-Sectional Study
Authors: Liu Yiran , Wang Shuzhen , Liu Jun , Su Mingrui , Diao Xiaoli , Liang Xiaolong , Zhang Jianxin , Wang Qiuxi , Zhan Yuxin 
Published: September 2023

Abstract
Background
To prevent overtreatment of patients whose cervical intraepithelial neoplasia(CIN) may be regression and to predict the onset of invasive cervical cancer at an early stage, we've identified the vaginal microbiome as a potential key factor, which is associated with both HPV infection and the various cervical intraepithelial neoplasia. This study aims to investigate the microbiome characteristics of patients with various cervical intraepithelial neoplasia.
Methods
Utilizing high-throughput 16S ribosomal RNA (16S rRNA) sequencing technology, an evaluation of the characteristics and community composition of VMB was conducted among 692 Chinese women infected with the High-risk Human Papillomavirus (HR-HPV).
Results
Among the VMB of female patients in the four groups, the genus Lactobacillus was the most abundant but significantly reduced in high-grade lesions. With the increase in the grade of lesions, the proportions of the genera Gardnerella, Dialister and Prevotella significantly increased. The diversity of the VMB was more significant in high-grade CIN. Furthermore, KEGG pathway enrichment analysis indicates that high-grade cervical intraepithelial neoplasia can inhibit various pathways, including those of phosphotransferase system, transcription factors, Fructose and mannose metabolism, amino sugar and nucleotide sugar metabolism, and galactose metabolism, which may contribute to the development of early cervical cancer symptoms.
Conclusion
Patients with CIN exhibit a distinct vaginal microbial profile. Decreased Lactobacillius, coupled with increased Gardnerella, Prevotella and Dialister, could may be relative with the cervical carcinogenesis.
Retrospectively registered: This study was approved by the Ethics Committee of the Beijing Chaoyang Hospital affiliated with the Capital Medical University (NO.2023-S-415).
Prevalence and risk factors of Cognitive dysfunction -associated Sarcopenia：A systematic review and meta-analysis
Authors: wang yifei , Li Ming-Lin , Zhang Fei , Quan Zi-Wei , Luo Han-Yong , Huang Le-Tian , Wang Jia-He 
Published: September 2023

Abstract

Background
Even though sarcopenia and cognitive dysfunction(including mild cognitive impairment(MCI) and Alzheimer's disease (AD)) have an impact on each other, there is limited evidence regarding their correlation. Moreover, we currently lack information about the prevalence of cognitive dysfunction-related sarcopenia. Therefore, our objective was to conduct a systematic search to determine the prevalence of sarcopenia among individuals with cognitive disabilities. Additionally, we aimed to consolidate the overall prevalence rate of cognitive dysfunction-related sarcopenia by considering various factors such as age, country, and diagnostic criteria for sarcopenia.
Methods
To achieve this goal, we performed a thorough search of several databases, including Web of Science, PubMed, Embase, and Cochrane Library. The search concluded on December 31, 2022, with the inclusion of studies that reported the prevalence of sarcopenia in patients with cognitive dysfunction. We then conducted a meta-analysis using all the collected data. All the statistical analyses were carried out using the STATA 15.0 version software.
Results
A total of 1,870 articles were initially evaluated. Eventually, 12 articles were included in our study[1–12]. The cumulative sample size across all the included studies amounted to 3,975 participants. All 12 studies employed a cross-sectional design. Consequently, the combined prevalence rate was estimated to be 16.96% (with a 95% confidence interval of 0.122 to 0.278), displaying considerable heterogeneity (I2 = 98.17%).Regarding the sample of patients with MCI and sarcopenia, the prevalence of MCI patients with sarcopenia was found to be 10.24% (95%CI: 0.44 − 0.209). Moreover, within the sample of Alzheimer's disease (AD) patients with sarcopenia, the pooled prevalence of AD individuals with sarcopenia was determined to be 21.09% (95%CI: 0.131–0.299).
Conclusions
Our findings highlight the frequent occurrence of sarcopenia among individuals with cognitive dysfunction, and the prevalence of sarcopenia appears to vary according to the degree of cognitive dysfunction. These results hold significance as they provide valuable insights for researchers planning studies on sarcopenia within this population. Urgent attention should be given to conducting longitudinal studies that focus on sarcopenia and its outcomes in patients with cognitive dysfunction.
A shape parameter approximation for the problem of thermal orientation and simulation in the additive manufacturing process
Authors: González-Martín Adrián , Barea Rafael , Corbera Sergio 
Published: September 2023

Abstract
Part orientation in Additive Manufacturing (AM) technology is a crucial process for the quality of a part. Orientation affects the manufacturing time, the amount of support, and the thermo-mechanical properties. To support the manufacturing process and to establish the best orientation at the lowest thermal gradient, an index is defined. This thermal index considers the temperature change when the part is rotated and is composed of several sub-indices based on the geometrical information of an STL (Standard Triangle Language) file. The thermal index was tested with two cases studies a cone and a sand clock in a finite element simulation which showed that the thermal index is related to the thermal gradient in the AM process. Finally, it was integrated into a work frame with a complex part to solve the part orientation problem.
Evaluation of anti-angiogenic effects of 5HT2A rec antagonist in xenograft model of colon cancer and expression of VEGF,NfKB,BAX,Caspase9 and Bcl2
Authors: Hosseinzadeh Fatemeh , Fattahi Esamil , Ghalehnoei Hossein , Ramin Ataee 
Published: September 2023

Abstract
Background
. One of the most common cancers of the gastrointestinal tract is colorectal cancer, according to some studies, serotonin can play a proliferative role by stimulating the cAMP-dependent MAPK pathwayAlso there are some evidences about role of 5HT receptors in some cancers as gastrointestinal,breast and bladder and breast cancers .
Objective
According to these backgrounds,we have aimed to investigate the effect of 5HT2A receptor antagonist (ritanserin) on expression of apoptotic and angiogenesis factors as (VEGF,NfKB) and Bax and Bcl2 in an In vivo model in nude mice .
Methods
The drugs were injected into mice for 21 days, and intradermal tumor was induced by injecting 10,000,000(HT29) suspension of colorectal cell into the flank muscle of nude mice. Tumor size were examined macroscopically three times a week. After three weeks, the mice were killed and the tumor tissue was removed and the Real-time PCR method was used to evaluate the angiogenic genes of VEGF and NfKB and Bax,Caspas9 and Bcl2 protein expression. The DATA analyzed by Friedman test and One-way ANOVA and post TUKEY-TEST with 21 SPSS software with P value < 0.05
Results
In There was a significant difference in the expression of bcl2 gene in the drug groups compared to the control group P < 0.05.The expression of bcl2 gene in drug groups has decreased compared to the control group,P < 0.05.The results of Kruskal-Wallis test in the expression of caspase9 gene showed inequality in the mean expression of caspase9 gene in the groups. The effect of ritanserin on the expression of angiogenesis factors in cells isolated from nude mice by RT-PCR showed that the level of the expression of nfkb in ritanserin group (4/73) and cis group (0/17) was lower than rit-cis groups(13/88) and control(1/00)The expression level of VEGF factor in rit group (3.26) was lower than cis group (4.90) which indicates the inhibitory effect of ritanserin is evenly more than positive control(cisplatin)on the expression of angiogenesis genes.
Conclusion
Our study has shown that Ritanserin as 5HT2A receptor antagonist has anti-tumor and anti-angiogenic effect in xenograft model in nude mice which some parts of its' effect could be through inhibition of NfKB as an inflammatory factor and VEGF as angiogenic factor and also through affecting on apoptotic factors as Bax,Bcl2 and Caspase9.
Altered peripheral taste function in a mouse model of inflammatory bowel disease
Authors: Dong Guangkuo , Boothe Khaylie , He Lianying , Shi Yang , McCluskey Lynnette Phillips 
Published: September 2023

Abstract
Increased sugar intake and taste dysfunction have been reported in patients with inflammatory bowel disease (IBD), a chronic disorder characterized by diarrhea, pain, weight loss and fatigue. It was previously unknown whether taste function changes in mouse models of IBD. Mice consumed dextran sodium sulfate (DSS) during three 7-day cycles to induce chronic colitis. DSS-treated mice displayed signs of disease, including significant weight loss, diarrhea, loss of colon architecture, and inflammation of the colon. After the last DSS cycle we assessed taste function by recording electrophysiological responses from the chorda tympani (CT) nerve, which transmits activity from lingual taste buds to the brain. DSS treatment significantly reduced neural taste responses to natural and artificial sweeteners. Responses to carbohydrate, salt, sour or bitter tastants were unaffected in mice with colitis, but umami responses were modestly elevated. DSS treatment modulated the expression of receptor subunits that transduce sweet and umami stimuli in oral taste buds as a substrate for functional changes. Dysregulated systemic cytokine responses, or dysbiosis that occurs during chronic colitis may be upstream from changes in oral taste buds. We demonstrate for the first time that colitis alters taste input to the brain, which could exacerbate malnutrition in IBD patients.