bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multi‐omics approach to understand the impact of sun exposure on an in vitro skin ecosystem and evaluate a new broad‐spectrum sunscreen
Authors: Jacques Carine , Bacqueville Daniel , Jamin Emilien L. , Maitre Martine , Delsol Cécile , Simcic‐Mori Aimée , Bianchi Pascale , Noustens Anais , Jouanin Isabelle , Debrauwer Laurent , Bessou‐Touya Sandrine , Stockfleth Eggert , Duplan Hélène 
Published: July 2023

AbstractA reconstructed human epidermal model (RHE) colonized with human microbiota and sebum was developed to reproduce the complexity of the skin ecosystem in vitro. The RHE model was exposed to simulated solar radiation (SSR) with or without SPF50+ sunscreen (with UVB, UVA, long‐UVA, and visible light protection). Structural identification of discriminant metabolites was acquired by nuclear magnetic resonance and metabolomic fingerprints were identified using reverse phase‐ultra high‐performance liquid chromatography–high resolution mass spectrometry, followed by pathway enrichment analysis. Over 50 metabolites were significantly altered by SSR (p < 0.05, log2 values), showing high skin oxidative stress (glutathione and purine pathways, urea cycle) and altered skin microbiota (branched‐chain amino acid cycle and tryptophan pathway). 16S and internal transcribed spacer rRNA sequencing showed the relative abundance of various bacteria and fungi altered by SSR. This study identified highly accurate metabolomic fingerprints and metagenomic modifications of sun‐exposed skin to help elucidate the interactions between the skin and its microbiota. Application of SPF50+ sunscreen protected the skin ecosystem model from the deleterious effects of SSR and preserved the physiological interactions within the skin ecosystem. These innovative technologies could thus be used to evaluate the effectiveness of sunscreen.
Activity level by clinical severity and sex differences in patients with Alzheimer disease and mild cognitive impairment
Authors: Kamizato Chiaki , Osawa Aiko , Maeshima Shinichiro , Kagaya Hitoshi , Arai Hidenori 
Published: July 2023

AbstractBackgroundTo determine how to maintain activity in persons with dementia and mild cognitive impairment, we examined the daily activity level by different degrees of clinical severity and sex differences in patients with Alzheimer's disease and mild cognitive impairment.MethodsThis study included 92 patients with Alzheimer's disease and 33 patients with mild cognitive impairment who visited our rehabilitation department. The Frenchay Activities Index was used to assess the level of activity.ResultsWomen had high Frenchay Activities Index scores for household activities, such as meal preparation, washing clothes, and light housework, whereas men had high Frenchay Activities Index scores for social occasions and walking outside. Although activity decreased with the severity of dementia in women, there was no difference in men. Additionally, a negative correlation was observed between the number of people living together and activity in women.ConclusionsTo maintain and improve activities in persons with Alzheimer's disease and mild cognitive impairment, it is important to suggest activities that fit the lifestyle of the individual and family caregivers and to provide lifestyle instructions that consider sex differences.
Correlation between sentence topic and discourse topic in French and Chinese: annotation issues and contrastive analysis
Authors: Hou Jiaqi , Landragin Frédéric 
Published: July 2023

AbstractThis paper aims to investigate the correlation between “sentence topic (ST)” and “discourse topic (DT)”, both based on an “aboutness” relation. It also compares the degrees of correlation between French and Chinese, considered respectively as a subject‐prominent and a topic‐prominent language. Kendall's correlation tests, Poisson models and z‐tests were conducted using manually annotated textual data. The results confirm a positive correlation between STs and DTs in both languages. Although the correlation coefficients are higher in Chinese, z‐tests' results do not show a significant difference between the two languages. We explain that the two languages differ not only in the more or less frequent topic‐comment constructions, but also in the choice of more or less accessible referential markers which represent the STs, or in the more or less tacit way that STs of different sentences are related to each other.
Multi‐hazard assessment using machine learning and remote sensing in the North Central region of Vietnam
Authors: Nguyen Huu Duy , Dang Dinh‐Kha , Bui Quang‐Thanh , Petrisor Alexandru‐Ionut 
Published: July 2023

AbstractNatural hazards constitute a diverse category and are unevenly distributed in time and space. This hinders predictive efforts, leading to significant impacts on human life and economies. Multi‐hazard prediction is vital for any natural hazard risk management plan. The main objective of this study was the development of a multi‐hazard susceptibility mapping framework, by combining two natural hazards—flooding and landslides—in the North Central region of Vietnam. This was accomplished using support vector machines, random forest, and AdaBoost. The input data consisted of 4591 flood points, 1315 landslide points, and 13 conditioning factors, split into training (70%), and testing (30%) datasets. The accuracy of the models' predictions was evaluated using the statistical indices root mean square error, area under curve (AUC), mean absolute error, and coefficient of determination. All proposed models were good at predicting multi‐hazard susceptibility, with AUC values over 0.95. Among them, the AUC value for the support vector machine model was 0.98 and 0.99 for landslide and flood, respectively. For the random forest model, these values were 0.98 and 0.98, and for AdaBoost, they were 0.99 and 0.99. The multi‐hazard maps were built by combining the landslide and flood susceptibility maps. The results showed that approximately 60% of the study area was affected by landslides, 30% by flood, and 8% by both hazards. These results illustrate how North Central is one of the regions of Vietnam that is most severely affected by natural hazards, particularly flooding, and landslides. The proposed models adapt to evaluate multi‐hazard susceptibility at different scales, although expert intervention is also required, to optimize the algorithms. Multi‐hazard maps can provide a valuable point of reference for decision makers in sustainable land‐use planning and infrastructure development in regions faced with multiple hazards, and to prevent and reduce more effectively the frequency of floods and landslides and their damage to human life and property.
Oral transmission of Chagas disease from a One Health approach: A systematic review
Authors: López‐García Alejandra , Gilabert Juan A. 
Published: July 2023

AbstractObjectiveTo analyse acute Chagas disease (CD) outbreaks through a qualitative systematic review and discuss the determinants for its prevention and control.MethodsReview of studies in which clinical cases of oral transmission were confirmed by parasitological and/or serological tests that included an epidemiological investigation of sources of infection, vectors and reservoirs.ResultsThirty‐two outbreaks (1965–2022) were analysed. The main foods involved in oral transmission outbreaks are homemade fruit juices. Different species of vectors were identified. Reservoirs were mainly dogs, rodents and large American opossums (didelphids).ConclusionUnder a One Health approach, environmental changes are one of the factors responsible of the rise of oral transmission of CD. Entomological surveillance of vectors and control of the changes in wild and domestic reservoirs and reinforcement of hygiene measures around food in domestic and commercial sites are needed.
Variables affecting surgeons’ use of, and preferences for, instrumentation in veterinary laparoscopy
Authors: Smith Meghan R. , Buote Nicole J. , Sumner Julia P. , Freeman Lynetta J. 
Published: July 2023

AbstractObjectiveTo investigate the impact of variables on use and preference of common laparoscopic instruments.Study designOnline survey.Sample populationSurgeons (n = 140) with 3 years or more laparoscopic experience.MethodsElectronic survey distributed via specialty group LISTSERVEs and Facebook groups. Responses collected included surgeon attributes, preferences, and surgical practice data. Statistical analysis was performed using Fishers exact, ANOVA, Tukey Kramer honestly significant difference (HSD) test, linear regression, and logistic regression.ResultsNinety‐eight of 140 respondents answered instrument‐related questions and the completion rate of these questions was 76%: 48% of females and 49% of males responded to the survey. The median glove size of respondents was size 7 (range, 5.5 to 8.5). Closing laparoscopic Babcock forceps (p = .018), rotating cup biopsy forceps (p = .003), and manipulating endoscopic staplers (p < .001) were more difficult for surgeons with smaller glove sizes. The median difficulty score for the endoscopic stapler was 4/10 and the median percentage of time this was found difficult was 25%. Reusable instruments were preferred over disposable single‐use instruments. The pistol grip was preferred for grasping and retracting (54/98, 55%) and fine dissection (46/96, 48%), while the axial grip was preferred for suturing and knot tying (61/98, 62%).ConclusionSurgeons with smaller glove sizes (<6.5) experience more difficulty when using common laparoscopic instruments. The endoscopic stapler was the most difficult to use.Clinical significanceWhen purchasing laparoscopic instrumentation, surgeons should review all available options in handle size and design to improve ergonomics during minimally invasive procedures.
Acceptance of xenotransplantation by patients waiting for organ donation: A qualitative study
Authors: Şahin Akboğa Özlem , Rukiye Hobek Akarsu 
Published: July 2023

AbstractBackgroundThe aim of this study was to determine the acceptance and barriers to xenotransplantation in patients waiting for organ transplantation.MethodsIt is qualitative and descriptive research. It was completed with 18 patients receiving treatment and waiting for organ transplantation in a dialysis center located in the inner region of Turkey between January 26, 2023 and February 3, 2023. Data were collected with an introductory information form and a semi‐structured interview form. The research data were collected through face‐to‐face in‐depth interviews. The content analysis method was used to analyze the data. In line with the goal of reaching data saturation, in‐depth interviews were conducted with 18 participants who were open to communication.ResultsTwo main themes, “Values” and “Thoughts”, and five sub‐themes, “social and religious values, positive, negative and future thoughts”, were identified. Thirteen codes were created including “not being understood by the society, xenotransplantation prejudice, fear of ridicule and exclusion, religious pressure, desire for unconditional acceptance/rejection” and “thought of survival, hope, thought of sinning, submission to doctors, the attitude of religious men and excessive demand”.ConclusionsPatients awaiting organ transplantation need religious, social, and community support for xenotransplantation.
ThePhyloCode: The logical outcome of millennia of evolution of biological nomenclature?
Authors: Laurin Michel 
Published: July 2023

AbstractBiological nomenclature harks back to a remote prehistoric past, as shown by the universality of fairly sophisticated folk taxonomies and nomenclatures found on all inhabited continents. Ethnobiologists have suggested that these nomenclatures include cryptic ‘ethnotaxonomic ranks’, although the existence of these ranks has been increasingly questioned recently. The fact that no trace of such ranks has been evoked in Aristotle's classification of animals but that they have been described in antique Roman ethnotaxonomies casts further doubts about these cryptic ranks. The advent of rank‐based nomenclature (RN) in the mid‐18th century has had a pervasive, but not only positive, influence on biological nomenclature. The use of a single type and of a subjective, artificial nomenclatural rank does not delimit taxa under RN. This is even a goal of RN, according to Principle 2 of theZoological Code. This contrasts with the nomenclatures of other fields, some of which are designed to delimit entities fairly precisely (e.g. geopolitics, stratigraphy, chemistry), and in which ranks are either defined more objectively (e.g. geopolitics, chemistry), or used informally and relegated to a secondary role (e.g. biogeography, paleobiogeography), or vary in time (e.g., paleobiogeography) or space (e.g., stratigraphy). A trend towards more explicit and precise delimitation of entities over time is also discernible in some fields, especially geopolitics and stratigraphy. In this context, the development of phylogenetic nomenclature (PN) and the recent advent of thePhyloCodeappear as the logical outcome of the development of evolutionary biology and phylogenetics.
The electromagnetic waves generated by a cluster of nanoparticles with high refractive indices
Authors: Cao Xinlin , Ghandriche Ahcene , Sini Mourad 
Published: July 2023

AbstractWe estimate the electromagnetic field generated by a cluster of dielectric nanoparticles embedded into a background made up of a vacuum. The dielectric nanoparticles are small scaled but enjoy high contrast of their relative permittivity. Such scales/contrasts can be ensured using the Lorentz model with incident frequencies chosen appropriately close to the undamped resonance frequency (appearing in the Lorentz model). Under certain ratio between their size and contrast, these nanoparticles generate resonances, called dielectric resonances. These resonances are characterized and computed via the spectrum of the electric Newtonian potential operator, stated on the support of nanoparticles, and projected on the space of divergence‐free fields with vanishing boundary normal components. We characterize the dominant field generated by a cluster of such dielectric‐resonating nanoparticles. In this point‐interaction approximation, the nanoparticles can be distributed to occupy volume‐like domains or low‐dimensional hypersurfaces where periodicity is not required. The form of these approximations suggests that the effective electromagnetic medium, equivalent to the cluster of such nanoparticles, is a perturbation of the magnetic permeability and not the electric permittivity. The cluster can be tuned such that the equivalent permeability has positive or negative values (while the permittivity stays unchanged).
Dynamics of the System Drilling Riser–BOP–Well Casing—Wellhead Casing Fatigue Analysis
Authors: Guimarães Fabiano 
Published: July 2023

Abstract
This paper presents a fully coupled solution in the time-domain, using the finite-differences method to the system of equations that model the dynamic behavior of the riser, blow-out preventer (BOP), and casing strings, when connected for well drilling/completion—the model is suitable to evaluate wellhead fatigue, even when the amplitude of oscillation and accelerations of the BOP are high. Sensibility analysis is used to show the effect of changing the Riser Top Tension to the resulting maximum values of wellhead bending moment and casing stress ranges. For the case where the rig is oscillating around a fixed position and there is no current, using a regular wave, the results show that there are some wave periods for which an increase in the Riser Top Tension reduces the maximum wellhead bending moment and the max casing stress range, therefore increasing fatigue life of the casing and wellhead. The effects of varying the weight of the BOP and soil parameters and the effect of the phase difference between the wave and first-order vessel motion are analyzed. The proposed solution can also be used to perform riser and casing analysis during drift-off/drive-off.
Evaluation of Power Transmission Lines Hardening Scenarios Using a Machine Learning Approach
Authors: Montoya-Rincon Juan P. , Gonzalez-Cruz Jorge E. , Jensen Michael P. 
Published: July 2023

Abstract
The power transmission infrastructure is vulnerable to extreme weather events, particularly hurricanes and tropical storms. A recent example is the damage caused by Hurricane Maria (H-Maria) in the archipelago of Puerto Rico in September 2017, where major failures in the transmission infrastructure led to a total blackout. Numerous studies have been conducted to examine strategies to strengthen the transmission system, including burying the power lines underground or increasing the frequency of tree trimming. However, few studies focus on the direct hardening of the transmission towers to accomplish an increase in resiliency. This machine learning-based study fills this need by analyzing three direct hardening scenarios and determining the effectiveness of these changes in the context of H-Maria. A methodology for estimating transmission tower damage is presented here as well as an analysis of impact of replacing structures with a high failure rate with more resilient ones. We found the steel self-support-pole to be the best replacement option for the towers with high failure rate. Furthermore, the third hardening scenario, where all wooden poles were replaced, exhibited a maximum reduction in damaged towers in a single line of 66% while lowering the mean number of damaged towers per line by 10%.
Path Planning for Autonomous Systems Design: A Focus Genetic Algorithm for Complex Environments
Authors: Hu Chuanhui , Jin Yan 
Published: July 2023

Abstract
Path planning has been a hot research topic in robotics and is a vital functionality for autonomous systems. As the time complexity of traditional path planning algorithms grows rapidly with the complexity of the problem, evolutionary algorithms are widely applied for their near-optimal solutions. However, evolutionary algorithms can be trapped in a local optimum or converge to infeasible solutions, especially for large search spaces. As the problem scale increases, evolutionary algorithms often cannot find feasible solutions with random exploration, making it extremely challenging to solve long-range path-planning problems in environments with obstacles of various shapes and sizes. For long-range path planning of an autonomous ship, the current downsampling map approach may result in the disappearance of rivers and make the problem unsolvable. This paper introduces a novel area-based collision assessment method for genetic algorithm (GA) that can always converge to feasible solutions with various waypoints in large-scale and obstacle-filled environments. Waypoint-based crossover and mutation operators are developed to allow GA to modify the length of the solution during planning. To avoid the premature problem of GA, the mutation process is replaced by a self-improving process to let the algorithm focus the operations on any potential solutions before discarding them in the selection process. The case studies show that the proposed GA-focus algorithm converges faster than RRT* and can be applied to various large-scale and challenging problems filled with obstacles of different shapes and sizes, and find high-quality solutions.
A Pilot Study of Exercise Training for Children and Adolescents With Inflammatory Bowel Disease: An Evaluation of Feasibility, Safety, Satisfaction, and Efficacy
Authors: Bjelica Mila , Walker Rachel G. , Obeid Joyce , Issenman Robert M. , Timmons Brian W. 
Published: July 2023

Background: Children with inflammatory bowel disease (IBD) experience extraintestinal side effects including altered body composition, impaired muscle strength, and aerobic capacity. Exercise training may remedy these issues. Purpose: To assess the feasibility, safety, participant satisfaction, and efficacy of a training program for youth with IBD. Methods: Children with IBD completed 16 weeks of training (2 supervised + 1 home sessions per week). Feasibility was assessed by tracking recruitment, adherence, and compliance rates. Safety was assessed by tracking symptoms and adverse events. Posttraining interviews gauged satisfaction. Circulating inflammatory markers, body composition, muscle strength, aerobic fitness, and habitual physical activity were measured at baseline, midtraining (8 wk), and posttraining. Results: Eleven youth were recruited and 10 completed the study. Participants adhered to 28 (1) of 32 prescribed supervised sessions and 8 (4) of 16 prescribed home sessions. There were no adverse events, and overall feedback on training was positive. Posttraining, we observed an increase in lean mass (+2.4 [1.1] kg), bone density (+0.0124 [0.015] g·cm−2), aerobic fitness (+2.8 [5.7] mL·kg LM−1· min−1), and vigorous physical activity levels (+13.09 [8.95] min·h−1) but no change in inflammation or muscle strength. Conclusion: Supervised exercise training is feasible, safe, and effective for youth with IBD and should be encouraged.
Family experiences of antenatal counselling of spina bifida: a systematic review
Authors: Agrawal Shreya , Hobson Esther V , Hart Anthony Richard 
Published: July 2023

ObjectiveTo describe families’ experiences of antenatal counselling of spina bifida.DesignSystematic review.MethodsMEDLINE, CINAHL, PsycINFO and Embase databases were searched using a combination of Medical Subject Headings and text/abstract terms. Case reports, survey results and qualitative interview data were included. The quality of research was evaluated using the Critical Appraisal Skills Programme checklist.Results8 papers were included. Families described shock and grief at diagnosis, with some immediately offered termination of pregnancy (TOP) even though they knew little about the condition. Positive and negative aspects of care were found. Teams that were gentle, kind and empathetic, who did not use jargon, and highlighted positive and negative aspects of the baby’s life were seen favourably. Callous language, and overly negative or incorrect counselling was not, particularly if there was pressure to agree to TOP. Families based their decisions on how they would cope, the effect on siblings and the baby’s likely quality of life. Prenatal surgery was viewed positively. The views of families who chose TOP, were happy with their care, partners, families, and the LGBTQ+ community were under-represented in the literature.ConclusionsUnlike other conditions where limited data on outcome exist or the spectrum is genuinely broad, the outcomes of children with spina bifida is well described. Poor aspects of antenatal counselling were described frequently by families, and further work is needed to capture the full spectrum of views on antenatal counselling, how it can be improved, and what training and resources healthcare professionals need to perform it better.