bluuebunny/crossref_metadata_2025_split huggingface dataset:
No Longer Indigenous
Authors: Shalley Fiona , Griffiths Kalinda , Wilson Tom 
Published: June 2023

AbstractInvestigating individual level-Indigenous identification change by Aboriginal and Torres Strait Islander Australians has been enabled through the linkage of census data across time. This study focusses on the population who moved from an identification of Indigenous in the 2011 census to not Indigenous in the 2016 census. We calculated transition probabilities for a range of personal characteristics to investigate the influence of broad life-course transitions on the pattern of identification change. In addition to age, we found that sex, employment, mixed ancestry, interstate migration, and living arrangements had the strongest associations with the risk of a transition to not Indigenous. The highest transition probabilities were at each end of the adult life-course and the role of “not stated” was implicated, destabilising assumptions that decisions to identify as Indigenous, or not, always reflect personal agency. Finally, the paper challenges the adequacy of an origin-based identity question to define the increasingly complex ethnic histories of Aboriginal and/or Torres Strait Islander people. Both improved definition and enumeration of Indigenous Australians are fundamental to current national conversations about constitutional recognition and continuing gaps in measured health and wellbeing.
The prediction of cancer-specific mortality in T1 non-muscle-invasive bladder cancer: comparison of logistic regression and artificial neural network: a SEER population-based study
Authors: Ślusarczyk Aleksander , Zapała Piotr , Olszewska-Ślusarczyk Zofia , Radziszewski Piotr 
Published: June 2023

Abstract
Purpose
To identify the risk factors for 5-year cancer-specific (CSS) and overall survival (OS) and to compare the accuracy of logistic regression (LR) and artificial neural network (ANN) in the prediction of survival outcomes in T1 non-muscle-invasive bladder cancer.

Methods
This is a population-based analysis using the Surveillance, Epidemiology, and End Results database. Patients with T1 bladder cancer (BC) who underwent transurethral resection of the tumour (TURBT) between 2004 and 2015 were included in the analysis. The predictive abilities of LR and ANN were compared.

Results
Overall 32,060 patients with T1 BC were randomly assigned to training and validation cohorts in the proportion of 70:30. There were 5691 (17.75%) cancer-specific deaths and 18,485 (57.7%) all-cause deaths within a median of 116 months of follow-up (IQR 80–153). Multivariable analysis with LR revealed that age, race, tumour grade, histology variant, the primary character, location and size of the tumour, marital status, and annual income constitute independent risk factors for CSS. In the validation cohort, LR and ANN yielded 79.5% and 79.4% accuracy in 5-year CSS prediction respectively. The area under the ROC curve for CSS predictions reached 73.4% and 72.5% for LR and ANN respectively.

Conclusions
Available risk factors might be useful to estimate the risk of CSS and OS and thus facilitate optimal treatment choice. The accuracy of survival prediction is still moderate. T1 BC with adverse features requires more aggressive treatment after initial TURBT.
Successful editing and maintenance of lactogenic gene expression in primary bovine mammary epithelial cells
Authors: Moody Janelle , Mears Emily , Trevarton Alexander J. , Broadhurst Marita , Molenaar Adrian , Chometon Thaize , Lopdell Thomas , Littlejohn Matthew , Snell Russell 
Published: June 2023

AbstractIn vitro investigation of bovine lactation processes is limited by a lack of physiologically representative cell models. This deficiency is most evident through the minimal or absent expression of lactation-specific genes in cultured bovine mammary tissues. Primary bovine mammary epithelial cells (pbMECs) extracted from lactating mammary tissue and grown in culture initially express milk protein transcripts at relatively representative levels. However, expression drops dramatically after only three or four passages, which greatly reduces the utility of primary cells to model and further examine lactogenesis. To investigate the effects of alternate alleles in pbMECs including effects on transcription, we have developed methods to deliver CRISPR-Cas9 gene editing reagents to primary mammary cells, resulting in very high editing efficiencies. We have also found that culturing the cells on an imitation basement membrane composed of Matrigel, results in the restoration of a more representative lactogenic gene expression profile and the cells forming three-dimensional structures in vitro. Here, we present data from four pbMEC lines recovered from pregnant cows and detail the expression profile of five key milk synthesis genes in these MECs grown on Matrigel. Additionally, we describe an optimised method for preferentially selecting CRISPR-Cas9-edited cells conferring a knock-out of DGAT1, using fluorescence-activated cell sorting (FACS). The combination of these techniques facilitates the use of pbMECs as a model to investigate the effects of gene introgressions and genetic variation in lactating mammary tissue.
Onsite versus home-office: differences in sleep patterns according to workplace
Authors: Staller Naomi , Quante Mirja , Deutsch Helen , Randler Christoph 
Published: June 2023

Abstract
Background and objective
This study aimed to evaluate the sleep patterns of students and employees working onsite versus those working from home during the COVID-19 pandemic using actigraphy.

Methods
A total of 75 students/employees (onsite: N = 40, home-office: N = 35; age range: 19–56 years; 32% male; 42.7% students, 49.3% employees) were studied between December 2020 and January 2022 using actigraphy, a sleep diary, and an online questionnaire assessing sociodemographics and morningness–eveningness. Independent-sample t-tests, paired-sample tests, and a multivariate general linear model adjusting for age (fixed factors: sex and work environment) were applied.

Results
Overall, onsite workers had significantly earlier rise times (7:05 [SD: 1:11] versus 7:44 [1:08] hours) and midpoints of sleep (2:57 [0:58] versus 3:33 [0:58] hours) on weekdays compared to home-office workers. Sleep efficiency, sleep duration, variability of sleep timing, and social jetlag did not differ between the groups.

Discussion
Home-office workers showed a delay in sleep timing that did not affect any other sleep parameters such as sleep efficiency or nighttime sleep duration. The work environment had only marginal impact on sleep patterns and thus sleep health in this sample. Sleep timing variability did not differ between groups.
Behavioral response of three subterranean pests (Agriotes lineatus, Diabrotica virgifera virgifera, Phyllopertha horticola) to the fungal volatile organic compounds 1-octen-3-ol and 3-octanone
Authors: Bourdon Pierre-Antoine , Zottele Maria , Zafar Zeeshan , Baxter Ian , Midthassel Audun , Myrta Arben , Wechselberger Katharina F. , Strasser Hermann , Butt Tariq M. 
Published: June 2023

AbstractThe volatile organic compounds (VOCs) 1-octen-3-ol and 3-octanone produced by the entomopathogenic fungus Metarhizium brunneum are known to have pesticidal properties at high doses against a range of invertebrate pests. Very little is known about their behavior-modifying (semiochemical) properties. This study focused on investigating the behavioral responses of three subterranean crop pests, wireworm (Agriotes lineatus), western corn rootworm (Diabrotica virgifera virgifera), and garden chafer (Phyllopertha horticola), to relatively low doses of 1-octen-3-ol and 3-octanone. The behavior of wireworms and corn rootworms were slightly influenced by the VOCs, yet not significantly. Western corn rootworms appeared to be slightly attracted by 100 µl and 200 µl 1-octen-3-ol and 100 µl dose of 3-octanone, respectively but slightly repelled by the higher dose of 3-octanone. Wireworms appeared to be slightly repelled by 1-octen-3-ol and high dose 3-octanone, but slightly attracted by the 100 µl dose of 3-octanone. The VOCs had no significant impact on garden chafer. In silico studies showed that corn rootworm odorant binding proteins (OBPs) had a strong binding affinity of 1-octen-3-ol and high dose 3-octanone, indicating that these VOCs can be detected and recognized by corn rootworm. OBPs are well conserved between species; thus, wireworm and garden chafer OBPs should also be able to bind with the VOCs. Further trials will be done to confirm that VOCs could be used as semiochemicals. Appropriate formulation of the VOCs should increase their efficacy and prevent rapid dissipation of the VOCs.
Beyond Crisis: Understandings of Vulnerability and Its Consequences in Relation to Intimate Partner Violence
Authors: Zimmermann Nesa 
Published: June 2023

AbstractThis article takes a closer look at intimate partner violence (IPV) and its semantical, political, and legal interactions with crisis and crisis discourse. Starting from the fact that IPV has been called a “shadow pandemic” and a “hidden crisis”, the article conceptualizes two parallel phenomena: how the COVID-19 pandemic — and crises in general — impact on IPV by exacerbating vulnerabilities and how crisis discourse has been mobilized to argue for a responsive state and strong positive obligations to combat and reduce IPV. The article then draws a parallel between crisis discourse and vulnerability reasoning, analyzing how vulnerability has played a similar role within the case law of the European Court of Human Rights (ECtHR) and led the latter to develop a consistent strand of case law concretizing states’ positive obligations. The article also takes a critical stance, examining the risks of crisis discourse and vulnerability when viewed through a crisis lens. To counter these risks, it argues for a nuanced, structural, and dynamic understanding of vulnerability and a focus on resilience-building institutions and mechanisms. Within the ECtHR case law, this signifies elaborating upon the already existing positive obligations, including by taking inspiration from the Council of Europe Convention on preventing and combating violence against women and domestic violence (Istanbul Convention). Such an approach is necessary to leave behind the emergency time usually associated with crises and work toward lasting structural change.
Revisiting Maher’s One-Factor Theory of Delusion
Authors: Nie Chenwei 
Published: June 2023

AbstractHow many factors, i.e. departures from normality, are necessary to explain a delusion? Maher’s classic one-factor theory argues that the only factor is the patient’s anomalous experience, and a delusion arises as a normal explanation of this experience. The more recent two-factor theory, on the other hand, contends that a second factor is also needed, with reasoning abnormality being a potential candidate, and a delusion arises as an abnormal explanation of the anomalous experience. In the past few years, although there has been an increasing number of scholars offering a variety of arguments in defence of Maher’s one-factor theory, these arguments have not been adequately addressed by two-factor theorists. This paper aims to address this gap by critically examining the arguments on three crucial issues: the intelligibility of delusions, the dissociation between anomalous experiences and delusions, and the empirical evidence of a second factor. I will argue that the Maherian notion of anomalous experience is not sufficient for explaining delusions and the two-factor theory is on the right track in its search for the missing factor in the aetiology of delusions.
Borderline Gradient Continuity for the Normalized p-Parabolic Operator
Authors: Akman Murat , Banerjee Agnid , Munive Isidro H. 
Published: June 2023

AbstractIn this paper, we prove gradient continuity estimates for viscosity solutions to $$\Delta _{p}^N u - u_t= f$$

Δ

p

N

u
-

u
t

=
f

in terms of the scaling critical $$L(n+2,1 )$$

L
(
n
+
2
,
1
)

norm of f, where $$\Delta _{p}^N$$

Δ

p

N

is the game theoretic normalized $$p-$$

p
-

Laplacian operator defined in (1.2) below. Our main result, Theorem 2.5 constitutes borderline gradient continuity estimate for u in terms of the modified parabolic Riesz potential $$\textbf{P}^{f}_{n+1}$$

P

n
+
1

f

as defined in (2.9) below. Moreover, for $$f \in L^{m}$$

f
∈

L
m

with $$m>n+2$$

m
>
n
+
2

, we also obtain Hölder continuity of the spatial gradient of the solution u, see Theorem 2.6 below. This improves the gradient Hölder continuity result in Attouchi and Parviainen (Commun Contemp Math 20(4):1750035, 2018) which considers bounded f. Our main results Theorem 2.5 and Theorem 2.6 are parabolic analogues of those in Banerjee and Munive (Commun Contemp Math 22(8):1950069, 2020). Moreover differently from that in Attouchi and Parviainen (Commun Contemp Math 20(4):1750035, 2018), our approach is independent of the Ishii–Lions method which is crucially used in Attouchi and Parviainen (Commun Contemp Math 20(4):1750035, 2018) to obtain Lipschitz estimates for homogeneous perturbed equations as an intermediate step.
A Scoping Review Using the Almere Model to Understand Factors Facilitating and Hindering the Acceptance of Social Robots in Nursing Homes
Authors: Felding Simone Anna , Koh Wei Qi , Teupen Sonja , Budak Kübra Beliz , Laporte Uribe Franziska , Roes Martina 
Published: June 2023

AbstractSocial robots are increasingly used in the care of older adults, including people living with dementia. An important prerequisite for effective use is knowledge about which factors facilitate and hinder the acceptance of social robots. The aim of this review at the intersection of health care research and human–robot interaction research is to understand factors facilitating and hindering the acceptance of social robots for older adults and people living with dementia in nursing homes based on the Almere model and to identify research gaps. We conducted a scoping review, systematically searching MEDLINE, PsycINFO, CINAHL and Compendex. The Almere model of acceptance was used to guide the development and conduct of this review. We used the principles of deductive content analysis, and we narratively present the review results. Twenty-six studies were included in the review. We found facilitating and/or hindering factors for all constructs of the Almere model. Perceived usefulness, perceived ease of use and perceived enjoyment were the most studied constructs, whereas trust and intention to use were the least studied constructs. Across constructs, seeing robots positively impacting residents was one of the key facilitating factors, and practical difficulties were a hindering factor. The Almere model provided useful insight into the acceptance of social robots. Nevertheless, we found the concept of engagement, the nursing home context, the intervention characteristics and the individual user groups important for the acceptance of social robots in nursing homes and therefore argue for future research expanding on the model.
First contributions of Donato García as Mineralogy Professor at the Royal Cabinet of Natural History of Madrid (Spain) in the Nineteenth Century
Authors: Alcalde-Fuentes María Rosario , Giménez Rosario García , Jiménez-Martínez Ramón , Pérez-Valera Juan Alberto 
Published: June 2023

AbstractDonato García
was the mineralogy professor at the Royal Cabinet of Natural History and Central University of Madrid from 1816 to 1853. In addition to teaching mineralogy, he gathered geological and mineralogical material for didactic purposes, and for exhibitions in the hall of the Cabinet. He was a key figure in developing the subject matter of mineralogy in Spain during the first half of the nineteenth century. Donato Garcia likewise promoted the careers of very important future teachers at the Military Academy of Engineers, Natural Sciences Museums, and Universities, integrating oral lectures, mineral testing, visual recognition, and the use of crystallographic models. This paper investigates how the crystallographic system proposed by Haüy (in the mid-thirties) was assimilated through unpublished documents of Donato García’s mineralogical lessons from 1824 to 1825, obtained from Spain’s Archivo General de Palacio (Madrid). Hence, this manuscript can be considered the first scientific work reliably attributable to Donato and based on the notes of his pupil José Musso y Valiente, which stands as an early attempt to create a handbook of mineralogy in Spanish. The novel approach to teaching mineralogy is furthermore compared with lessons published by disciple Antonio María Cisneros y Lanuza in 1843.
Preparation and Characterization of Dental Pit and Fissure Sealant Based on Calcium Sodium Silicate Bioactive Glasses
Authors: Safwat Engie M. , Alkabani Yasmine M. , Zaki Dalia Y. , Elbatanony Mai M. , Abd-Elsatar A. G. , Saleh Reham S. , Khater G. A. 
Published: June 2023

AbstractThis study aimed to prepare a resin based dental sealant loaded with novel bioactive glass formulated from (50 wt% calcium silicate and 50 wt% sodium silicate) with different percentages of fluorapatite. Four glass batches were formulated then characterized using Fourier Transform Infrared Spectroscopy analysis, X-ray powder diffraction analysis and Transmission electron microscopy. Density, microhardness and bioactivity testing after insertion in artificial saliva were done. Four bisphenol A-glycidyl methacrylate (Bis-GMA) based sealants loaded with the glass batch that showed the preeminent properties and silica fillers were prepared. The prepared sealants were compared to commercial sealants regarding flow, curing depth, compressive strength and microhardness. Sealant composition that showed comparable properties to that of the commercial sealant was selected for pH changes and ion release testing after immersion in artificial saliva for different time intervals. Results indicated amorphous nature, bioactive behavior and apatite forming ability of the tested glass batches. Experimental sealant revealed comparable tested properties with lower compressive strength compared to the commercial sealants at P < 0.001. The mean pH values of the tested sealants ranged from 6.75 to 6.35 with extended calcium and phosphorus ion release up to 90 days. It was concluded that the 85 wt% calcium silicate and sodium silicate with 15 wt% fluorapatite had the best trend regarding ion release and apatite forming ability. Sealant loaded with 65 wt% bioactive glass, 10 wt% sintered nanosilica and 10 wt% nanosilica had the best acceptable mechanical properties. The novel pit and fissure sealant is a promising bioactive and ion releasing material.
One-year outcome of transcatheter aortic valve replacement for bicuspid aortic valve stenosis: a report from the Japanese Nationwide registry (J-TVT registry)
Authors: Mukai Takashi , Kumamaru Hiraku , Kohsaka Shun , Mizote Isamu , Nakamura Daisuke , Matsuhiro Yutaka , Maeda Koichi , Shimamura Kazuo , Sakata Yasushi 
Published: June 2023

AbstractThe outcome of transcatheter aortic valve replacement (TAVR) for patients with bicuspid aortic valve (BAV) remains unclear, particularly among Asian patients that are known to have different valvular morphology and lower body habitus. This study investigated patient characteristics, procedural and 1-year outcome of TAVR for BAV within national TAVR registry in Japan. The patient‐level data were extracted from the J-TVT (Japanese Transcatheter Valvular Therapy) registry between August 2013 and December 2018; overall, there were 423 patients (2.5%) with BAV and 16,802 patients with tricuspid aortic valve (TAV). At baseline, patients with BAV were younger and had less arteriosclerotic comorbidities. There was no statistically significant difference between BAV and TAV groups in conversion to surgery (0.5% vs. 1.1%, p = 0.34) and 30-day mortality (0.5% vs. 1.3%, p = 0.18). Cumulative all-cause survival and survival from major adverse events were analyzed. Cox proportional hazard regression model was used to estimate the hazard ratio. All-cause mortality and major adverse event rate at 1 year were comparable between the two groups. Relative hazard for all-cause mortality for BAV compared to TAV was 1.01 (0.70–1.45; p = 0.96), and for major adverse event was 0.94 (0.69–1.27; p = 0.67). From the Japanese nationwide TAVR registry, procedural and 1-year outcome of TAVR in BAV was as favorable as TAVR in TAV.
Structural characterizations and α-glucosidase inhibitory activities of four Lepidium meyenii polysaccharides with different molecular weights
Authors: Wen Luan , Wu Zhou-Wei , Lin Li-Wu , Al-Romaima Abdulbaset , Peng Xing-Rong , Qiu Ming-Hua 
Published: June 2023

AbstractFour polysaccharides (MCPa, MCPb, MCPc, MCPd) were obtained from Lepidium meyenii Walp. Their structures were characterized by chemical and instrumental methods including total sugar, uronic acid and protein content determination, UV, IR and NMR spectroscopy, as well as monosaccharide composition determination and methylation analyses. Four polysaccharides were a group of glucans with different molecular weights ranging from 3.12 to 14.4 kDa, and shared a similar backbone chain consisting of (1→4)-glucose linkages with branches attached to C-3 and C-6. Furthermore, bioactivity assay showed that MCPs had concentration-dependent inhibitory activity on α-glucosidase. MCPb (Mw = 10.1 kDa) and MCPc (Mw = 5.62 kDa) with moderate molecular weights exhibited higher inhibitory activity compared with MCPa and MCPd.
Graphical Abstract
Numerical simulation of near wellbore fracture propagation in interbedded continental shales with competing perforations
Authors: Qin Yong , Shi Xian , Shan Qinglin , Li Mukun , Han Songcai , Gao Qi 
Published: June 2023

AbstractTo reduce near wellbore fracture complexity in continental laminated shales, in-plane perforations completion technology is introduced. The global embedded cohesive elements are capable to simulating arbitrary fracture propagation growth while the laminae effects on fracture propagation path can be considered in established finite element model. Numerical simulations reflect that the existence of weak micro fractures only locally alter the fracture propagation path but laminae can change the fracture propagation path greatly. Furthermore, the in-situ stress anisotropy, pump rate, perforation intersection angle and perforation angle with laminae are critical factors for affecting the fracture propagation path and breakdown pressure. There is a great impact of laminae on the fracture branching at the contact interface and hydraulic fracture tends to cross laminae at high approaching angle but propagate horizontally along laminae at low approaching angle. In most cases, hydraulic fracture tends to propagate along the laminae rather than across the laminae. The adjustment of pump rate, fluid viscosity, perforation intersection angle and perforation angle with laminae can enhance the possibilities of hydraulic fracture across laminae. It was also found that hydraulic fractures induced from different perforations can interact and overlap with each other, resulting in different fracture geometry and pressure behavior for individual fracture. The fracture width of interior fracture is almost close at the near wellbore zone at the end of pumping, and exterior fractures generally deviated away from the perforation tunnel direction because of stress interference of neighboring fractures. Additionally, although a fracture initiated initially from a perforation tunnel to short distance, hydraulic fractures still finally would reorient itself to maximum principle in-situ stress direction, thus increase more chances of creating one large and main fracture along the maximum principle in-situ stress orientation with larger horizontal stress contrast. Therefore, the existence of laminae can enhance the potential of fracture complexity near wellbore but the selection of suitable perforation scenarios in one defining plane can increase the possibility of form a main fracture. The simulation results from this study offer some important insights to hydraulic fracturing design with multiple perforations on interbedded continental shales stimulation.