bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of dynamic methods for calculating NPP building structures
Authors: Korotkov V. A. 
Published: July 2023

Introduction. The present article concerns the seismic performance of various building structures, including NPP objects. The provided materials generalize the results of the author’s longstanding work connected with the dynamics of building structures.Aim. To analyze the seismic performance of various building structures, including NPP objects, and represent the author’s material on the dynamics of building structures.Materials and methods. The presented materials include a definition of the dynamics concept, computational modeling of dynamic processes, main correlations of dynamic analysis methods, and a description of impacts (accelerograms). In addition, the concepts of resonance and vibration diagnostics in the dynamic analysis, assessment of the building strength and stability, as well as the description of applied software systems are provided. Some of the presented materials are characterized by the scientific novelty. The following methods were used in the study. The method of nonclassical modal superposition for determining the response of a structure under dynamic impacts together with floor response spectra were presented by the author at the ABAQUS (SIMULIA) International Conference in Barcelona, 2011. The essence of the method consists in the reliable account for a “soil” damper, modeling the energy outflow into the soil during the vibrations of a building, which ensures reliable results. A fundamental solution for accounting the ductility of the foundation slab under seismic impacts was applied. This method ensures the seismic response of the structure to be reliably determined, as well as the floor response spectra to be obtained in the conditions of the aircraft crashing for buildings, whose impact on the equipment is transmitted through the foundation slab. Additionally, the method of accounting the dynamic characteristics of building fragments (floor/ wall), obtained using the vibration diagnostic results, was applied to verify computational models, as well as to analyze the strength and floor response spectra. The appendix includes the realistic test problem of the seismic analysis, developed by the author.Results. The provided materials generalize the results of the author’s longstanding work in the field of NPP building structures. In addition to the scientific novelty, the materials are widely applied in the development of NPP designs both in the Russian Federation and abroad.Conclusion. The materials, presented in the article, can be used to prepare the “Introduction to Dynamics” lecture course, including, for newcomer countries that are at the beginning of the nuclear facility (NF) construction.
Immunoassay Detects Salivary Anti-SSA/Ro-52 Autoantibodies in Seronegative Patients with Primary Sjögren’s Syndrome
Authors: Kamounah Sarah , Tayob Nabihah , Chiang Samantha , Wei Fang , Park Jin Kyun , Kwon Hyun Mi , Feng Ziding , Chia David , Pedersen Anne Marie Lynge , Song Yeong Wook , Wong David T W 
Published: July 2023

Abstract
The diagnostic work-up for Sjögren’s syndrome is challenging and complex, including testing for serum autoantibodies to SSA/Ro and a labial salivary gland biopsy. Furthermore, the diagnosis is often delayed. In this study, we tested the hypothesis that anti-SSA/Ro autoantibodies are detectable in the saliva of patients with primary Sjögren’s syndrome (pSS) because the disease affects the salivary glands, and these autoantibodies display greater discriminatory performance in saliva than in serum. SSA/Ro-52 Ags were used to develop what is, to our knowledge, a novel quantitative electrochemical-based immunoassay: the electric field–induced release and measurement (EFIRM) platform. The clinical utility was determined by measuring salivary anti-SSA/Ro-52 autoantibodies in patients with pSS and sicca (n = 34), patients without pSS with sicca (n = 35), and healthy subjects (n = 41). The statistical analysis of discrimination included the area under the receiver operating characteristic curve. Salivary anti-SSA/Ro-52 autoantibodies were measured in 94% (32 of 34) of patients with pSS with 85% (29 of 34) seropositivity. Four of the five seronegative patients with pSS had EFIRM-measurable anti-SSA/Ro-52 autoantibodies in saliva. Additionally, 60% (21 of 35) of the seronegative patients without pSS who had sicca had EFIRM-detectable SSA/Ro-52 autoantibodies in saliva, indicating the onset of autoimmune disease. Two of the 41 healthy control subjects had EFIRM-detectable SSA/Ro-52 autoantibodies in their saliva. Salivary SSA/Ro-52 autoantibodies significantly discriminated patients with pSS or patients with the initial stage of autoimmune disease from healthy subjects with an area under the receiver operating characteristic curve of 0.91. Our findings suggest that the proposed saliva SSA/Ro-52 immunoassay improves early and accurate diagnosis of seronegative patients with pSS and patients with early-onset autoimmune disease.
Assessment of the impacts of cloud chemistry on surface SO2 and sulfate levels in typical regions of China
Authors: Lu Jianyan , Gong Sunling , Zhang Jian , Chen Jianmin , Zhang Lei , Zhou Chunhong 
Published: July 2023

Abstract. A regional online chemical weather model, Weather Research and Forecasting (WRF)/China Meteorological
Administration Unified Atmospheric Chemistry Environment (CUACE), is used to assess
the contributions of cloud chemistry to the SO2 and sulfate levels in
typical regions of China. Upon comparison with several time series of in situ
cloud chemical observations on Mountain Tai in Shandong Province of China,
the CUACE cloud chemistry scheme is found to reasonably reproduce the
observed cloud consumption of H2O2, O3, and SO2 and the
production of sulfate, and it is consequently used in the regional assessment
of a heavy pollution episode and monthly average of December 2016. During
the cloudy period in the heavy pollution episode, sulfate production increased by 60 %–95 % and SO2 production reduced by over 80 %. The cloud
chemistry mainly affects the middle and lower troposphere below 5 km as well
as within the boundary layer, and it contributes significantly to the SO2
reduction and sulfate production in central-east China. Among these four
typical regions in China, the Sichuan Basin (SCB) is the most affected by the
cloud chemistry, with an average SO2 abatement of about 1.0–10.0 ppb
and sulfate increase of about 10.0–70.0 µg m−3, followed by the Yangtze
River Delta (YRD) and the southeast of the North China Plain (NCP), where SO2
abatement is about 1.0–5.0 ppb and sulfate increase is about 10.0–30.0 µg m−3. However, the cloud chemistry contributions to the Pearl River
Delta (PRD) and the northwest of the NCP are not significant due to lighter
pollution and less water vapor than the other regions.
An empirical model to calculate snow depth from daily snow water equivalent: SWE2HS 1.0
Authors: Aschauer Johannes , Michel Adrien , Jonas Tobias , Marty Christoph 
Published: July 2023

Abstract. Many methods exist to model snow densification in order to calculate the depth of a single snow layer or the depth of the total snow cover from its mass. Most of these densification models need to be tightly integrated with an accumulation and melt model and need many forcing variables at high temporal resolution. However, when trying to model snow depth (HS) on climatological timescales, which is often needed for winter tourism-related applications, these preconditions can cause barriers. Often, for these types of applications, empirical snow models are used. These can estimate snow accumulation and snowmelt based on daily precipitation and temperature data only. To convert the resultant snow water equivalent (SWE) time series into snow depth, we developed the empirical model SWE2HS. SWE2HS is a multilayer densification model which uses daily snow water equivalent as sole input. A constant new snow density is assumed and densification is calculated via exponential settling functions. The maximum snow density of a single layer changes over time due to overburden and SWE losses. SWE2HS has been calibrated on a data set derived from a network of manual snow stations in Switzerland. It has been validated against independent data derived from automatic weather stations (AWSs) in the European Alps (Austria, France, Germany, Switzerland) and against withheld data from the Swiss manual observer station data set which was not used for calibration. The model fits the calibration data with root mean squared error (RMSE) of 8.4 cm, coefficient of determination (R2) of 0.97, and bias
of −0.3 cm; it is able to achieve RMSE of 20.5 cm, R2 of 0.92, and bias of 2.5 cm on the validation data set from automatic weather stations and
RMSE of 7.9 cm, R2 of 0.97, and bias of −0.3 cm on the validation data set from manual stations. The temporal evolution of the bulk density can be reproduced reasonably well on all three data sets. Due to its simplicity, the model can be used as post-processing tool for output of any other snow model that provides daily snow water equivalent output. Owing to its empirical nature, SWE2HS should only be used in regions with a similar snow climatology as the European Alps or has to be recalibrated for other snow climatological conditions. The SWE2HS model is available as a Python package which can be easily installed and used.
Identifying mountain permafrost degradation by repeating historical electrical resistivity tomography (ERT) measurements
Authors: Buckel Johannes , Mudler Jan , Gardeweg Rainer , Hauck Christian , Hilbich Christin , Frauenfelder Regula , Kneisel Christof , Buchelt Sebastian , Blöthe Jan Henrik , Hördt Andreas , Bücker Matthias 
Published: July 2023

Abstract. Ongoing global warming intensifies the degradation of permafrost. Permafrost
thawing impacts landform evolution, reduces freshwater resources, enhances
the potential of natural hazards and thus has significant socio-economic
impacts. Electrical resistivity tomography (ERT) has been widely used to map
the ice-containing permafrost by its resistivity contrast compared to the
surrounding unfrozen medium. This study aims to reveal the effects of
ongoing climate warming on mountain permafrost by repeating historical ERT
and analyzing the temporal changes in the resistivity distribution. In order
to facilitate the measurements, we introduce and discuss the employment of
textile electrodes. These newly developed electrodes significantly reduce
working effort, are easy to deploy on blocky surfaces and yield
sufficiently low contact resistances. We analyze permafrost evolution on
three periglacial landforms (two rock glaciers and one talus slope) in the
Swiss and Austrian Alps by repeating historical surveys after 10, 12 and 16 years, respectively. The resistivity values have been significantly reduced
in ice-poor permafrost landforms at all study sites. Interestingly,
resistivity values related to ice-rich permafrost in the studied active rock
glacier partly increased during the studied time period. To explain this
apparently counterintuitive (in view of increased resistivity) observation,
geomorphological circumstances, such as the relief and increased creep
velocity of the active rock glacier, are discussed by using additional
remote sensing data. The present study highlights ice-poor permafrost
degradation in the Alps resulting from ever-accelerating global warming.
Electrochemical Corrosion Study of Cold-Rolled AA8015-Alloy Processed by Reversing Cold Rolling Mill at Varying Surface Roughness
Authors: Olaogun Olayinka , Titilayo Akinlabi Esther , Samuel Abima Cynthia 
Published: July 2023

AA8015-alloy is a general-purpose aluminium alloy having a wide range of applications. Electrochemical corrosion testing of cold-rolled AA8015-alloy processed by reversing cold-rolling mill at different surface roughness in natural seawater were investigated. The AA8015-alloy utilised in this study was cold-rolled in a reversible Achenbach cold-rolling mill in four number of passes to a gauge thickness of 1.2 mm. This industrial cold rolling process was achieved at Tower Aluminium Rolling Mill, Sango-Ota, Nigeria. The different surface roughness’s each with three cold mounted samples, 1.54 μm, 0.83 μm, 0.18 μm and 0.04 μm were achieved on automated polishing machine using 320-grit, 800-grit, 1200-grit and diamond abrasive MD-Mol respectively. Electrochemical corrosion experiments were conducted on the samples in natural seawater using a computer-controlled potentiostat in an open polarisation cell set-up at room-temperature. The corrosion behaviour on surface morphologies of the samples was observed by high-mega-pixel camera and scanning electron microscope. Findings reveal asymmetric polarisation curves, and the polarisation resistance increases as the surface roughness decreases. Consequently, corrosion-rate reduces as the surface get smoother and EDS elemental analysis shows the existence of insoluble sulphate and chloride complexes formed on the surfaces. Conclusively, surface roughness affects the corrosion resistance of cold-rolled AA8015-alloy in natural seawater.
Effectiveness of a modified Balint group process on empathy and psychological skills employing Kirkpatrick’s evaluation framework
Authors: Antoun Jumana , Khater Beatrice , Itani Hala , Naous Jihane , Romani Maya 
Published: July 2023

Background
To evaluate, using Kirkpatrick’s evaluation model, a modified Balint group (BG) by adding 5–10 min at the end of the session, where the facilitators will debrief the residents about critical themes mentioned in the session.

Methods
A quasi-experimental study with a mixed-method design was conducted among family medicine residents over 1 year, using focus groups and validated tools filled by residents and their corresponding patients. The residents’ empathy through self and patient evaluation, psychological skills, and satisfaction with the educational activity were measured.

Results
The focus group revealed that the residents were aware of the change and considered it a closure to the encounter, helping decrease some uncertainty. Most of the residents did not consider the change helpful. Using validated instruments, BG was ineffective at improving the residents’ empathy and psychological skills. There was a statistically significant main effect of time on Psychological Medicine Inventory (PMI) scores, F (1,13) = 7.709, p = 0.016.

Conclusion
Debriefing at the end of BG by the facilitators about key themes may help give the residents closure, decrease the uncertainty, and make them more aware of their feelings. Nevertheless, Balint groups are still not very well accepted by the residents, and they prefer direct feedback and support groups.
Rational Design of a Chemical Bath Deposition Based Tin Oxide Electron‐Transport Layer for Perovskite Photovoltaics
Authors: Lu Yongli , Shih Meng‐Chen , Tan Shaun , Grotevent Matthias J. , Wang Lili , Zhu Hua , Zhang Ruiqi , Lee Joo‐Hong , Lee Jin‐Wook , Bulović Vladimir , Bawendi Moungi. G. 
Published: July 2023

AbstractChemical bath deposition (CBD) is widely used to deposit tin oxide (SnOx) as an electron‐transport layer in perovskite solar cells (PSCs). The conventional recipe uses thioglycolic acid (TGA) to facilitate attachments of SnOx particles onto the substrate. However, nonvolatile TGA is reported to harm the operational stability of PSCs. In this work, a volatile oxalic acid (OA) is introduced as an alternative to TGA. OA, a dicarboxylic acid, functions as a chemical linker for the nucleation and attachment of particles to the substrate in the chemical bath. Moreover, OA can be readily removed through thermal annealing followed by a mild H2O2 treatment, as shown by FTIR measurements. Synergistically, the mild H2O2 treatment selectively oxidizes the surface of the SnOx layer, minimizing nonradiative interface carrier recombination. EELS (electron‐energy‐loss spectroscopy) confirms that the SnOx surface is dominated by Sn4+, while the bulk is a mixture of Sn2+ and Sn4+. This rational design of a CBD SnOx layer leads to devices with T85 ≈1500 h, a significant improvement over the TGA‐based device with T80 ≈250 h. The champion device reached a power conversion efficiency of 24.6%. This work offers a rationale for optimizing the complex parameter space of CBD SnOx to achieve efficient and stable PSCs.
Quetiapine‐induced chest wall edema with the swellings of face and extremities in a young hospitalized patient: A case report
Authors: Elyasi Forouzan , Heydari Fatemeh , Haddadi Kaveh 
Published: July 2023

Key Clinical MessageQuetiapine can lead to the face, extremity and particularly chest wall edema in hospitalized patients in the supine position.AbstractQuetiapine (QTP) is known as an atypical antipsychotic agent with some adverse effects, such as edema. However, along this line, peripheral edema is not a life‐threatening episode, but it is an important side effect affecting medical compliance. Therefore, QTP‐induced chest wall edema with the swellings of the face and the extremities is very rare. This report is about a young man who was admitted in the intensive care unit with multiple trauma (MT). On account of his delirious state, QTP was started at 25 mg and then increased to 75 mg, three times a day. The patient developed swelling of the face, the upper and lower limbs, and the chest wall. After stopping the QTP use, his edema went down. Although there is still speculation about the possible mechanisms of antipsychotic‐induced edema, some studies have pointed to the relationship between dopaminergic antagonism and peripheral edema. Therefore, it is very important to pay close attention to this side effect.
Anti‐TNFα induced lupus due to infliximab therapy in a patient with concurrent Crohn's disease
Authors: Sharma Akanksha , Ahmed Taha , Mehta Aashna , Birnbaum Julius , Shrestha Abhigan Babu 
Published: July 2023

AbstractAnti‐TNFα inhibitor‐induced Lupus (ATIL) is a rare syndrome characterized by a wide array of symptoms ranging from skin manifestations to organ‐specific symptoms such as pleural effusions, pericardial effusions, hepatotoxicity, etc. Infliximab is implicated in most cases, and ATIL usually develops between the first month and 4 years of infliximab application. In this report, we present an interesting case of ATIL that developed rather gradually upon anti‐TNFa used to treat Crohn's disease. The patient presented with oral ulcers, photosensitive rash, diffuse alopecia, inflammation of the hands, and pleuritic chest pain. Comprehensive serological testing revealed the presence of antinuclear antibodies and anti‐DNA antibodies. During the evaluation, the patient developed headaches, followed by a brain MRI that suggested nonspecific white matter lesions. Given the chronic development of symptoms, invasive examinations such as an arteriogram were performed to exclude CNS vasculitis, which showed no evidence of the vasculitis. Therefore, in the absence of any clear radiographical signs of vasculitis, patients should not undergo invasive studies, including an angiogram. The CNS angiogram can be associated with several side effects, including damage to the blood vessel, bruising or bleeding at the puncture site, and infection, which can further aggravate ATIL. Although rare, ATIL should always be considered while evaluating a patient with suggestive symptoms on infliximab therapy. Further research on identifying the variety of clinical presentations of ATIL and the underlying pathophysiology can help improve health policy and clinical practice by reducing unnecessary examination and allowing early management and better‐quality care.
Investigations on the in vitro and in vivo metabolic fate of the new synthetic opioid desmethylmoramide using HPLC–HRMS/MS for toxicological screening purposes
Authors: Manier Sascha K. , Valdiviezo Johannes Angert , Eckstein Niels , Meyer Markus R. 
Published: July 2023

AbstractNew synthetic opioids are an increasing challenge for clinical and forensic toxicologists that developed over the recent years. Desmethylmoramide (DMM), a structural analogue of methadone, is one of the most recent appearances on the drug market. This study investigated its metabolic fate in rat and pooled human liver S9 fraction (pHLS9) to allow the identification of suitable urinary screening targets beyond the parent compound. The analysis of rat urine after the administration of DMM revealed five metabolites, which were the result of pyrrolidine ring or morpholine ring hydroxylation and combinations of them. Additionally, an N′,N‐bisdesalkyl metabolite was formed. Incubations of DMM using pHLS9 revealed a pyrrolidine hydroxy metabolite, as well as an N‐oxide. No Phase II metabolites were detected in either rat urine or incubations using pHLS9. The metabolism of DMM did in part comply with that of its archetype dextromoramide (DXM). Although morpholine ring hydroxylation and N‐oxidation were described for DXM and detected for DMM, phenyl ring hydroxylation was not found for DMM but described for DXM. An analysis of 24 h pooled rat urine samples after DMM administration identified the hydroxy and dihydroxy metabolite as the most abundant excretion products, and they may, thus, serve as screening targets, as the parent compound was barely detectable.
Color Doppler, HDlive, and HDlive Silhouette features of an umbilical cord cyst before 11 weeks of gestation: Diagnostic value
Authors: Hata Toshiyuki , Konishi Miyu , Kawahara Tomomi , Miyagi Yasunari , Miyake Takahito 
Published: July 2023

AbstractObjectiveWe describe transvaginal color Doppler, HDlive, and HDlive Silhouette features of an umbilical cord cyst (UCC) before 11 weeks of gestation.MethodsIn this cohort study, 135 transvaginal dating scans were performed at 7 to 10 + 6 weeks of gestation, and 17 UCCs were identified (12.6%). UCC was evaluated using color Doppler, HDlive, and HDlive Silhouette. The clinical characteristics, pregnancy courses, and outcomes were also investigated.ResultsUCC location was on the fetal side in six cases, at the free loop in 10 cases, and on the placental side in one case. There were seven single and 10 multiple cysts. Cyst diameters ranged from 3.3 to 11.3 mm (mean, 5.6; standard deviation, ±2.1). Blood flow inside the cyst was noted in three cases (17.6%). HDlive clearly showed the spatial relationships among UCC, the umbilical cord, midgut herniation, yolk sac, and embryo. Location of UCC could be clearly identified with HDlive. HDlive Silhouette showed central cysts inside UCCs in seven cases (41.2%). HDlive Silhouette also clearly demonstrated the sac of midgut herniation in the umbilical cord in 12 cases (70.6%). All UCCs resolved before 15 weeks (mean, 11.1 weeks; standard deviation, ±1.5). All fetuses with UCCs showed good neonatal outcomes.ConclusionThe incidence of UCC was high compared with that in previous reports. Color Doppler, HDlive, and HDlive Silhouette may provide information on the nature and origin of UCCs before 11 weeks of gestation. UCC before 11 weeks of gestation may be a common, transient, and benign finding.