bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hemolytic saponins product enhancement in Gnidia glauca (Fresen.) Gilg cell suspension cultures
Authors: E. Vishala , Kumar Vadlapudi , F. Ruksana , D. V. Poornima , C. M. Anuradha , H. M. Prathap , G. K. Pratap , M. Savitharani , T. Manjunatha 
Published: April 2023

Introduction and Aim: Gnidia glauca (Fresen.) Gilg of thymelaeaceae is enlisted as an endangered plant. Hemolytic triterpenoid saponins of oleanane and ursane classes are present in G. glauca. The purpose of the present study is to increase the production of hemolytic triterpenoids in vitro using salicylic acid as an elicitor in G. glauca cell suspensions.

Materials and Methods: Explants were collected and surface sterilized, then inoculated onto Murashige and Skoog medium for callus culture, further establishing suspension cultures that were treated with salicylic acid. Saponins produced in the suspension culture were extracted and analyzed by HPLC and FTIR. The hemolytic activity of saponins was confirmed by spectrophotometric assay in erythrocyte suspensions.

Results: Product enhancement of hemolytic triterpenoid saponins was observed in cell suspensions treated with salicylic acid that also induced concomitant change in medium pH compared to control set of culture. Results of HPLC and FTIR analyses confirm the presence of triterpenoid saponins in suspension culture extracts. The optimal concentration of salicylic acid was found to be 200 µM for product enhancement, pH alteration. Hemolytic saponins concentration was observed to be increased with increasing concentrations of elicitor supplemented to the medium.

Conclusion: Cell suspension is a viable alternative technique to produce the phytochemicals in vitro using elicitors that avoids destructive harvesting of endangered plants like G. glauca. Results of the present study demonstrate the large scale production of hemolytic saponins through cost-effective approaches.
PENINGKATAN AKTIVITAS DAN HASIL BELAJAR SISWA DALAM PEMBELAJARAN MATEMATIKA PADA POKOK BAHASAN SPtDV MENGGUNAKAN MODEL PEMBELAJARAN KOOPERATIF TIPE JIGSAW SMA NEGERI 1 JEMBER
Authors: RAHAYU ANIEK SUSI 
Published: April 2023

This study aims to increase student activity and learning outcomes in learning mathematics on the SPtDV subject using the Jigsaw type cooperative learning model of SMAN 1 Jember. This type of research is Classroom Action Research. The research subjects were 36 students of class X MIPA 5 at SMA Negeri 1 Jember. Data collection was carried out in September 2019 with class action activities using the jigsaw cooperative learning model, and formative test activities. The results of the data analysis show that the jigsaw type of cooperative learning tends to increase the learning activities carried out during teaching and learning activities in the classroom. This can be seen from the increase in student learning activeness from learning I to learning II of 3.49%. The learning outcomes of jigsaw cooperative learning compared to conventional learning using expository methods (lectures) also increased. The percentage of completeness of student learning outcomes classically has increased from 69.44% to 88.89
ABSTRAKPenelitian ini bertujuan untuk meningkatkan aktivitas dan hasil belajar siswa dalam pembelajaran matematika pada pokok bahasan SPtDV menggunakan model pembelajaran kooperatif tipe Jigsaw SMAN 1 Jember. Jenis penelitian ini merupakan Penelitian Tindakan Kelas. Subjek penelitian adalah 36 siswa kelas X MIPA 5 SMA Negeri 1 Jember. Pengambilan data dilaksanakan pada bulan september 2019 dengan kegiatan tindakan kelas menggunakan model pembelajaran kooperatif tipe jigsaw, dan kegiatan tes berupa formatif. Hasil analisis data menunjukkan bahwa pembelajaran kooperatif tipe jigsaw cenderung meningkatkan aktivitas belajar yang dilakukan selama kegiatan belajar mengajar di dalam kelas. Hal ini dapat dilihat dari peningkatan keaktifan belajar siswa dari pembelajaran I ke pembelajaran II sebesar . Hasil belajar pembelajaran kooperatif tipe jigsaw dibandingkan dengan pembelajaran konvensional menggunakan metode ekspositori (ceramah) juga mengalami peningkatan. Persentase ketuntasan hasil belajar siswa secara klasikal mengalami peningkatan dari 69,44% menjadi 88,89
Contrasting Features and Volcanostratigraphy of the Mafic-Hosted Mandoos and Shinas Volcanogenic Massive Sulfide Deposits, Samail Ophiolite, Oman
Authors: Cravinho André , Jesus Ana P. , Moreira Bruno , Mateus António , Pracejus Bernhard , Figueiras Jorge , Benoit Mathieu , Bauer Wilfried , Rocha Fernando 
Published: April 2023

AbstractDespite the substantial amount of research on the Cretaceous Samail ophiolite in Oman, the factors controlling the size and metal endowment of the mafic-hosted, Cu-Au(-Zn-Ag) volcanogenic massive sulfide (VMS) deposits remain elusive. This work shows that the volcanostratigraphic position, hydrothermal venting style, and oxidation processes are critical factors controlling the distinct features of the Shinas and Mandoos deposits.Mandoos is a large (8 Mt, 1.8 wt % Cu, 0.18 g/ton Au) orebody preserving abundant primary vent-related features formed via mound growth and collapse within a wide hydrothermal field, overlying a poorly developed stockwork. The smaller Shinas deposit (0.8 Mt, 2.6 wt % Cu, 0.63 g/t Au) represents a higher-temperature system evolving from low fS2/fO2 conditions, locally sealed by jaspers, to a mound growth stage with widespread subseafloor brecciation/replacement with associated zone refining. Mandoos formed at the onset of the postaxial stage (Geotimes-Tholeiitic Alley transition), and Shinas is hosted within the Alley units. Volcanism in Samail was seemingly continuous, and the low ɛNd and Nb/Ta of the Shinas hanging-wall lavas record the onset of significant modifications of the mantle source during the postaxial stage.Mandoos is enriched in Te + As + Se ± Zn ± Ga ± Sb relative to Shinas, where higher Cu + Au + Tl ± Mo grades possibly reflect leaching of protoarc-like lavas. Rare earth element patterns in the ores mimicking the deposit footwall can be employed to constrain volcanostratigraphic positioning and indicate that the footwall lavas may also represent a source of metals. Formation of metal-rich ochres at the sea floor likely led to Cu + Au upgrading in the ores during seawater-induced oxidation, which was enhanced during subaerial gossan formation.
Research on Unfriendly Comments Against Women on China's Microblog -- Taking Tangshan Hitting Event as An Example
Authors: Wang Ziqi , Xu Jiancheng 
Published: April 2023

Women's rights have been a hot topic for most people in recent years. It has aroused the attention of people from all walks of life in the society. This thesis focuses on the in-depth discussion of women's rights. This paper takes Tangshan beating incident as an example to discuss and analyze its fundamental problems and reasons in depth. This study employs mixed methods combines both qualitative methods and quantitative methods. The participants in this study were participating discussants on related superwordname on Weibo. The study will retrieve the keywords in their sentence on Weibo so as to obtain the views of different groups on the Tangshan beating incident, such as influencers in Weibo, disadvantaged groups, college students. The study focus on their views on social security and gender issues, and it enables participants to have a clear cognition of the public opinion on the Tangshan beating incident. These methodologies will make the paper get the opinions of different groups on the Tangshan beating incident, so as to help the researchers analyze the differences and reasons of social public opinion environment. The problem of females’ weak position remains unsolved because women are still trapped in the stereotype made by men, over which also being widely spread through the information exchange mechanism of network: classic features like gentle, thoughtful and obedient are what thought to define “a good woman”. Participants use an incidence happened in Tang Mountain to start a study. The purpose of the study is to trace the presented fact back to its origin of biases, hopefully contributing to the development of strategies that help build a more equal and inclusive network environment. All these studies and research help people realize the reality of females’ situation on the Internet and how they are affected by the guide of media.
Preface: 5th International Conference on Business, Economics, Management Science (BEMS 2023)
Authors: Wang Pin , Walton Chapman 
Published: April 2023

This proceeding includes original and peer-reviewed research papers from the 5th International Conference on Business, Economics, Management Science (BEMS 2023), and BEMS 2023 was held on March 11-12, 2023 in Singapore.
The aim of BEMS 2023 is to provide a platform for accountants, financial industry practitioners, scholars, managers and graduate students from different cultural backgrounds to present and discuss research, developments and innovations in all fields of business, economics, management. It provides opportunities for the delegates to exchange new ideas and application experiences, to establish business or research relations and to find global partners for future collaboration.
BEMS 2023 received 91 manuscripts. And more than 30 submissions had been accepted by our reviewers. By submitting a paper to this BEMS, the authors agreed to the review process and understood that papers undergo a peer-review process. Manuscripts were reviewed by appropriately qualified experts in the field selected by the Conference Committee, who gave detailed comments and-if the submission was accepted the authors would submit a revised version that considered this feedback. All papers were reviewed using a double-blind review process: authors declared their names and affiliations in the manuscript for the reviewers to see, but reviewers did not know each other’s identities, nor did the authors receive information about who had reviewed their manuscript. The Committees of BEMS 2023 invested great efforts in reviewing the papers submitted to the conference and organizing the sessions to enable the participants to gain maximum benefit.
With our warmest regards,
Pin Wang, Chapman Walton
Conference Committees
Analysis of Atour Lifestyle Holdings Limited and Its IPO
Authors: Zhao Xintong 
Published: April 2023

As the leader of the newly rising industry in China, Atour’s has brought the Chinese hotel market with a possibility. The mid-upper-class hotel and combined signed brand hotel. In November 2022, they announced IPO in NASDAQ and raised capital with 52 million dollars. In this paper, Atour’s main business, specialties, the analysis of its IPO event will be discussed. The aim is to provide investors with an idea whether Atour stock is a good stock to invest, why they success and the further improvement and challenges for them. Within the paper, SWOT is used to analysis the IPO event of Atour. Atour has a lot of specialties which makes them occupied the most market share in 2021. However, at the current environment, pandemic strikes back and forth, the ambitious plan of their competitors and even serious inside secret worries. Atour are facing challenges. Whether they could maintain the performance, maintain the best customers’ experience, lower the operating cost, expand with faster speed will be the further consideration for Atours’ management team.
Analysis Of The Use Of Self-Protective Equipment (PPE) In Boom Baru Port Of Palembang
Authors: Komalasari Yeti 
Published: April 2023

In an effort to implement work procedures safely and avoid working risks to loading and unloading activities, awareness of the loading and unloading workers (TKBM) is required to apply Occupational Safety and Health (K3) rules through the use of Personal Protective Equipment (PPE). The fact that occurs when this, the application of the use of Personal Protective Equipment (PPE) in loading and unloading activities at the Port is still lacking, even though the loading and unloading activities are high operational activities that can cause various risks of accidents, especially risks to occupational safety and health. The purpose of this study was to evaluate the process of implementing Occupational Safety and Health (K3) to Unloading Workers at the Boom Baru Port of Palembang through the use of Personal Protective Equipment (PPE). The study used survey questions and direct interviews in the field, followed by identification of project locations, visual surveys in the project and documentation taking in the field. Implementation of the use of Personal Protective Equipment (PPE). At the Boom Baru Port of Palembang, it has not been going well because of the lack of implementation of the supervisory function of the TKBM Cooperative and from the regulatory side of the Palembang Port Authority and Port Authority (KSOP).
Comparison Study between Fetal Kidney Length and Transcerebellar Diameter to Determine Gestational age in the Third Trimester
Authors: Ahmed Mounir Ahmed El-Saeed  , Walaa Mohammed El-Bassioune  , Abdelrahman Ali Hassan Emam  
Published: April 2023

Introduction and Aim: An accurate determination of gestational age (GA) is crucial to the management of all pregnancies, particularly high-risk pregnancies. This study aimed to comparing between the accuracy of ultrasonographic fetal kidney length and Transcerebellar diameter in GA determination in third trimester.
Patients and methods: The study was a cross sectional one, carried out at the department of Obstetrics and Gynecology, Damietta Faculty of Medicine, Al-Azhar University, Damietta, Egypt. The study had been performed between January 2021 and January 2022. All were submitted to a detailed history, routine antenatal investigations, general and obstetrical examination. Then, measurements of all fetal biometric parameters were recorded using a real- time, grayscale, 3.5–5.0 MHz curvilinear array transducer. Results were compared to the gestational age determined by last menstrual period.
Results: The patient age ranged between 18 and 37 years, their weight ranged between 55 and 109 kg, while gravidity ranged between 1 and 5 and parity ranged between 0 and 4. The GA as determined by last menstrual period (LMP) was ranged between 28 and 40 weeks. The calculated GA by different measurements were also included and they were around the same measurements as determined by LMP. This was confirmed by the absent statistically significant difference between GA by LMP and any of calculated gestational age by any method. The mean fetal kidney length is more accurate in determination of gestational age than transcerebellar diameter (96.3% vs 89.8%) and both were significantly correlated with other calculated gestational ages.
Conclusion: The length of the fetal kidney length proportionately correlated with fetal gestation age with powerful correlation coefficient. Fetal kidney length is found to be more accurate in GA determination than transcerebellar diameter (TCD).
Treatment of High Energy Tibial Plateau Fractures with Hybrid External Fixation
Authors: Elasas Ahmed Mahmoud , Ezzedeen Ashraf Eltabie , Hassan Mohamed Abdallah 
Published: April 2023

Objective: The current study aimed to assess the treatment results of high energy tibial plateau fractures with hybrid external fixation.
Methodology: It included 20 adult patients (17 males and 13 females). At emergency rooms, patients were clinically and radiologically evaluated according to standard protocols, then the assessment was completed and treatment was started in the inpatient department. Preoperative preparation was completed according to standard protocols. Then, the surgical fixation was performed and the patient scheduled for postoperative evaluation. Radiological evaluation had been achieved by anteroposterior and lateral X-ray of the knee and leg. Computed tomography and Doppler ultrasound were requested for specific patients when indicated. Routine laboratory investigations were carried out. All operations carried out under spinal anesthesia. The 1st follow up visit was at the 2nd week postoperative, and follow up was done every 2 weeks. In each visit, patient was assessed clinically and by radiological investigations.
Results: Five patients (25 %) had excellent, 8 patients (40%) had good, 2 patients (10 %) had fair, 5 patients (25%) had poor final result. In addition, 13 patients (65%) had no varus or valgus angulation, 18 patients (90 %) had 0-5mm limb shortening, 14 patients (70 %) had normal knee range of motion, 12 patients (60 %) had no pain and 14 patients (70 %) had normal gait. Two patients had non-union treated by removal of Ilizarov, proximal tibial locked plate, autologous iliac bone graft. 6 patients had multiple degrees of stiffness treated by physiotherapy and had fair, good outcomes, 3 patient had Pin track infection treated by surgical debridement with good outcome, 1 patient had deep vein thrombosis DVT treated by anticoagulant medication.
Conclusion: Hybrid external fixation is a safe and effective treatment modality for tibial plateau fractures.
Investigating the effects of individual and institutional factors on the research productivity of university academics: A comprehensive analysis
Authors: Muhammad Kamaruzzaman , Ghani Erlane K , Ilias Azleen , Ali Mazurina Mohd , Ismail Rina Fadhilah , Rohayati Suci , Susanti Susanti , Bahtiar Moh Danang 
Published: April 2023

Purpose: This study aims to examine the factors influencing the research productivity of academics in Malaysian universities. Specifically, this study examines whether individual and institutional factors can influence academics’ research productivity.
Design/Methodology/Approach: This study utilized a questionnaire survey as the research instrument, which was distributed to university academics in Malaysia.
Findings: This study demonstrates that institutional factors significantly influence the research productivity of university academics. The findings of this study suggest that institutional factors should be taken into consideration when developing strategies to increase the research productivity of university academics. However, the study did not find significant evidence to support the influence of individual factors on research productivity.
Conclusion: The results of this study constitute a timely addition to the body of knowledge on academic research output, which educational leaders of Malaysian public institutions can utilize.
Research Limitations/Implications: The outcomes of this study are expected to assist universities in developing strategies to assist and support academics in improving their research productivity.
Practical Implications: The findings imply that universities could raise awareness of the value of research among academics and support them through publication funding or training programs.
Contribution to Literature: This study contributes to the existing literature by providing evidence on the effect of individual and institutional factors on the academics’ research productivity.
Analysis of the relevance between computed tomography characterization and pathology of pulmonary ground-glass nodules with different pathology types
Authors: Youguo Zhang , Chengye Wang , Xiaofei Cheng , Xuefei Zhang , Changhong Liu 
Published: April 2023

Background: In this study, we aimed to analyze the relevance between computed tomography characterization and pathology of pulmonary ground-glass nodules with different pathology types.
Methods: Between January 2017 and December 2018, a total of 657 patients (191 males, 466 females; mean age: 60.9±8.1 years; range, 34 to 80 years) with pathologically diagnosed ground-glass nodules were retrospectively analyzed. The clinicopathological characteristics and computed tomography characterizations of patients with ground-glass nodules who received surgical resection were analyzed. The clinical data including age, sex, smoking status and medical history were recorded. Computed tomography characterizations included the location and size of the tumor, the size of the consolidation components, density uniformity, shape, margin, tumor-lung interface, internal signs and surrounding signs.
Results: Based on the computed tomography imaging characteristics, a mean computed tomography value of ?444.5 HU was more likely to indicate malignant lesions, while ?444.5 HU indicated benign lesions. A malignant ground-glass nodules" maximum diameter of <6.78 mm, a diameter of the consolidation component of <3.88 mm, and a mean computed tomography value of <-536.5 HU were more likely to indicate atypical adenomatous hyperplasia and adenocarcinoma in situ. A maximum diameter of malignant ground-glass nodules of >11.52 mm, a diameter of the consolidation component of >6.20 mm, and a mean computed tomography value of ?493.5 HU were more likely to indicate invasive adenocarcinomas. The focus between these parameters indicated minimally invasive adenocarcinomas.
Conclusion: Ill-defined tumor-lung interface, irregular in shape, and smooth nodule margins suggest benign lesions while round or oval, clear tumor-lung interface, spiculation signs, lobulation signs, bubble signs, air bronchograms, pleural indentations, and vessel convergences are helpful in the diagnosis of malignant lesions. A clear tumor-lung interface, the spiculation signs, lobulation signs, and bubble signs indicate the invasion of the lesions.
Prediction of malignancy in mediastinal lymph nodes during endobronchial ultrasound: A comparative validation study
Authors: Şafak Alıcı Nur , Onur Alıcı İbrahim 
Published: April 2023

Background: In this study, we aimed to compare the diagnostic performances of three existing prediction tools in visually identifying a malignant lymph node.
Methods: Between April 2016 and January 2021, a total of 827 lymph nodes of 259 patients (211 males, 48 females; mean age: 61.1±7.2 years; range, 41 to 79 years) who underwent endobronchial ultrasound procedure for diagnosis and/or staging of lung cancer and diagnosis of mediastinal lymphadenopathy of unknown origin were retrospectively analyzed. This external validation study was designed to compare the diagnostic yields of the prediction tools developed by Shafiek et al., Alici et al., and Canada Lymph Node Score (CLNS). Endobronchial ultrasoundguided transbronchial needle aspiration results and predictions were compared to gold-standard tool.
Results: Overall, endobronchial ultrasound-guided transbronchial needle aspiration had a sensitivity, specificity, positive and negative predictive value, and accuracy of 95.6%, 100%, 100%, 97.6%, and 98.4%, respectively. Diagnostic performances of proposed tools were quite remarkable. Among them, Alici algorithm had a higher sensitivity and negative predictive value, which were matched by excellent specificity and positive predictive value offered by CLNS ≥3 and Shafiek tool. The area under the curve value of CLNS ≥3 was higher than Shafiek tool and CLNS ≥2.
Conclusion: Conventional prediction tools relying on simple real-time sonographic features were found to be consistent by the means of diagnostic performance in this external validation dataset. Despite being inferior to cytology, their superior performance was proven with defined individual strengths and weaknesses.