bluuebunny/crossref_metadata_2025_split huggingface dataset:
A call in the dark: Nocturnal flight calls and their potential to advance the study of avian migration
Authors: Osterhaus Dylan M , Boland Kelley C , Horton Kyle G , Van Doren Benjamin M , Cutler Patricia L , Desmond Martha J , Wright Timothy F 
Published: January 2025

Abstract
Migratory birds have experienced widespread declines in abundance and face numerous threats. The conservation of migratory species relies in part on improved knowledge of active migration behavior, but this behavior is difficult to study as most birds migrate at night. Flight calls, which are species-specific calls produced by many nocturnal migrants during flight, offer an opportunity to improve our understanding of migration behavior and serve as a tool to monitor populations. Although nocturnal flight call monitoring has been historically limited to small spatial and temporal scales, recent technological advancements have allowed researchers to largely shed these constraints. Despite this expansion, there are many unanswered questions regarding the function of flight calls and the proximate drivers of calling behavior. There are also unaddressed concerns that the methods used to record nocturnal flight calls, as well as other organismal, environmental, and social factors, may bias data in ways that impede (or prohibit) comparisons across time and space. Research that addresses these limitations and potential sources of bias will advance the use of nocturnal flight call monitoring for migratory bird research.
Anti-Black and Blue: Neighborhood Identity and Local Racial Ideologies in Chicago’s Police Neighborhoods
Authors: Fox Anna 
Published: January 2025

Abstract
This article explores the relationship between the places police live and their local racial dynamics. Using geospatial data to estimate where Chicago’s police officers live, I find that police reside in distinct enclaves. Then, drawing on interviews with members of 60 police households, I show how a coherent “police” identity is applied to these neighborhoods. These enclaves were identified as “police neighborhoods” with a strong police identity that all residents could share–unless they were Black. In these neighborhoods, non-Black officers and their spouses used interpersonal surveillance to stigmatize Black residents, using the neighborhood-level police identity to justify localized forms of anti-Black racial exclusion. Although non-officers could wield a police identity in these neighborhoods, Black CPD officers were excluded from it, describing themselves as potential targets of racist policing and violence. The neighborhood-level police identity reveals a direct relationship between police identities and anti-Black racism and incentivizes even those who are not officially police to maintain an anti-Black racial order in police neighborhoods. This study illuminates how everyday people are empowered by their investment in and relationship to policing to enact various forms of racism. The police identity can expand to non-police actors, legitimizing civilian vigilantism and facilitating racial violence.
Challenging the Gender Regime through Small-scale Activism: Alternative Citizen-Led Projects in Kurdistan/Türkiye
Authors: Hamelink Wendelmoet , Şen Besime , Bocheńska Joanna , Kaczorowski Karol 
Published: January 2025

Abstract
This article investigates local initiatives among women in Kurdistan/Türkiye and labels them “small-scale activism,” and reports that they offer an alternative to state and party feminism, as well as to civil society organizations. We argue that, through small-scale political acts, women work on several levels simultaneously. First, their actions grow out of a dissatisfaction with the existing gender regime created by an interplay between various macro- and micro-forces (such as state structures, societal norms, economic opportunities, violence), producing structural inequalities. Second, the projects can be seen as political acts that simultaneously challenge or evade state oppression and Kurdish alternative politics. These micro-interventions grew in importance with the implementation of the Trustee system after the 2016 failed military coup. Theoretically, we position small-scale activism between social movement and social non-movement and show how it challenges the gender regime in the context of an authoritarian state and violent conflict.
Oral Cyclosporine in Vernal Keratoconjunctivitis: Indications, Outcomes, and Effect on Corticosteroid Use
Authors: Kate Anahita , Tallapelly Haritha Goud , Jain Neha , Yukti Kumari , Basu Sayan 
Published: January 2025

Purpose:
The purpose of this study was to report the indications and outcomes of oral cyclosporine A (oCsA) use in vernal keratoconjunctivitis (VKC) and to assess its effect on corticosteroid use.

Methods:
This retrospective review of VKC cases included patients who were prescribed oCsA. Data on clinical characteristics, demographic profile, and treatment were collected. An acute episode was defined as one requiring oral/topical corticosteroids. The outcome measure was the difference in the number of acute episodes before and after oCsA use.

Results:
The study included 27 cases (54 eyes) of VKC from 2016 to 2024. The median age was 20 years. Thirty eyes had sequelae due to VKC, the most common of which was limbal stem cell deficiency (46%). The median duration of follow-up was 11 months. Indications for oCsA were recalcitrant disease (23/27, 85%) and severe active allergy in steroid-induced glaucoma/steroid responders (4/27, 15%). None of the cases experienced progression of sequelae with oCsA use. Forty-two acute episodes were observed before oCsA initiation over 403 person-months, which reduced to 10 episodes over 250 person-months with oCsA use. Without oCsA use, the odds of developing an acute exacerbation of the ocular allergy were 2.6 times (95% confidence interval: 1.3–5.2) higher compared with that with oCsA usage.

Conclusions:
Oral cyclosporine reduces corticosteroid use in VKC and can be considered in recalcitrant disease or in eyes with steroid-induced glaucoma and active allergy. Oral cyclosporine significantly reduced the risk of acute exacerbations, proving to be an effective modality for controlling inflammation in VKC.
Could Nocturnal Chronic Hypoxia Cause Ocular Surface Symptoms by Affecting Limbal Epithelial Cells in Patients With Obstructive Sleep Apnea?
Authors: Yilmam İlker , Küpeli Çinar Ayça , Çinar Abdulkadir Can , Serez Kaya Bilkay 
Published: January 2025

Purpose:
To investigate the effect of nocturnal chronic hypoxia on the thickness changes of the corneal limbal epithelial area that provides regeneration of the corneal epithelium and ocular surface evaluation parameters in patients with obstructive sleep apnea (OSA).

Methods:
All patients diagnosed with OSA and the control group underwent a complete ophthalmological examination, including slit-lamp examination and funduscopy. Tear break-up time, Schirmer test-I, Ocular Surface Disease Index Questionnaire, and anterior segment optical coherence tomography were performed with fluorescein sterile strip for ocular surface evaluation.

Results:
Oxygenation levels of patients during night sleep were different between mild-severe and moderate-severe groups. The Ocular Surface Disease Index results were statistically significantly different between the severe OSA group and the mild OSA group, and between the control group and all other OSA groups (P < 0.05). The limbal epithelial thickness (LET) value was found to be lower in the moderate OSA group than in the mild OSA group and the control group and was statistically significantly higher than in the severe OSA group. In the severe OSA group, the LET value was found to be statistically significantly lower than all other groups (P < 0.05).

Conclusions:
In the literature, there is no study evaluating the effect of prolonged hypoxia on limbus epithelium as in patients with OSA. In this study, LET was measured to be statistically significantly thinner as the severity of OSA increased. Considering these results, it can be concluded that the proliferation of limbal stem cells is reduced in prolonged hypoxia.
Sex-Dependent Variations in Gene Expression in Corneal Endothelial Cells Among Healthy Individuals and Patients With Fuchs Endothelial Corneal Dystrophy
Authors: Nakagawa Tatsuya , Tateishi Ayana , Tokuda Yuichi , Nakano Masakazu , Tashiro Kei , Tourtas Theofilos , Schlötzer-Schrehardt Ursula , Kruse Friedrich , Koizumi Noriko , Okumura Naoki 
Published: January 2025

Purpose:
Fuchs endothelial corneal dystrophy (FECD) displays a higher incidence in females than in males, yet the underlying mechanism remains unclear. This study aimed to elucidate sex-dependent differential gene expressions in corneal endothelial cells (CECs) from healthy non-FECD individuals and from patients with FECD.

Methods:
RNA-Seq data from CECs of non-FECD subjects (3 males, 4 females) and FECD subjects (5 males, 5 females) were analyzed to identify differentially expressed genes (DEGs) between the sexes. We used heatmaps and principal component analysis for expression pattern visualization and Gene Ontology analysis for functional categorization of DEGs.

Results:
Among the non-FECD subjects, we identified 341 DEGs—143 upregulated and 198 downregulated—in females relative to males. For FECD subjects, 309 DEGs were discovered, with 215 upregulated and 94 downregulated in females compared with males. Heatmaps exhibited hierarchical clustering by sex, whereas principal component analysis delineated distinct male and female clusters in both non-FECD and FECD cohorts. Gene Ontology enrichment analysis linked the upregulated genes in non-FECD females to steroid hormone response, and downregulated ones to cyclin-dependent protein kinase activity. In females with FECD, upregulated genes were associated with immune responses and downregulated genes with peptide hormone binding.

Conclusions:
To our knowledge, these findings are the first to reveal distinct gene expression patterns in CECs between sexes. The observed variations suggest a potential genetic basis for the observed sex disparity in FECD prevalence. Further investigation is warranted to explore these associations and their implications for the pathogenesis of FECD.
Influence of Sex and Gender on Adherence to Self-care Behaviors for Cardiovascular Disease Risk Management in the Global Context
Authors: Orach Juma , Adhikari Shambhu P. , Dev Rubee 
Published: January 2025

Background
Adherence to self-care behaviors can prevent or delay adverse outcomes associated with cardiovascular disease (CVD). Sex and socioculturally constructed gender might impact individuals' ability to adhere to healthy lifestyles.

Objective
The aim of this study was to systematically identify, evaluate, and synthesize the literature on the influence of sex and gender on adherence to self-care behaviors for CVD risk management in the global context.

Methods
We searched the MEDLINE, EMBASE, CINAHL, Scopus, Web of Science, and Global Health Databases for peer-reviewed original articles published between 2013 and 2023. We selected studies that investigated self-care behaviors, self-care maintenance, or self-care management as outcomes and reported sex- and gender-related factors (such as education level, employment status, and marital status). The data were synthesized in a narrative form.

Results
The search identified 3540 studies, 52 of which met the inclusion criteria for full-text review. Global North countries accounted for 55% of all the studies. Self-reported questionnaire scores were used in most of the studies (n = 47). Better self-care was associated with being a woman (n = 17), attaining a higher education level (n = 15), and having higher perceived social support (n = 10). The associations between adherence to self-care behaviors and employment status, socioeconomic status, marital status, and household size were inconsistent.

Conclusions
Adherence to self-care behaviors for CVD risk management varied widely, based on gender-related factors. Further research is needed to use a consistent measure of self-care adherence behavior and integrate a wider range of gender-related factors.
Internet-based cognitive rehabilitation for working cancer survivors: A process evaluation
Authors: Klaver Kete M. , Duijts Saskia F.A. , Geusgens Chantal A.V. , Aarts Maureen J.B. , Ponds Rudolf W.H.M. , van der Beek Allard J. , Schagen Sanne B. 
Published: January 2025

ABSTRACT

Objective
To evaluate the process of an online cognitive rehabilitation program aimed at supporting cancer survivors experiencing cognitive problems at work.

Methods
Cancer survivors (n = 279) were randomized to one of the intervention groups (i.e., basic and extensive online cognitive rehabilitation) or waitlist control group. Recruitment, reach, dosage, implementation, perceived usefulness and experiences with the program were evaluated using questionnaires and logbooks.

Results
Implementation (i.e., reach multiplied by dosage) was acceptable for both versions of the program (range 63% to 76%). Cancer survivors and cognitive therapists perceived the overall program as moderately to highly useful and generally reported positive experiences.

Conclusions
Both a basic and extensive version of the online cognitive rehabilitation program were successfully implemented in the context of an RCT, suggesting their feasibility as intervention to support cancer survivors with cognitive problems at work.
PM2.5 Speciation chemicals and Neonatal Respiratory Distress Syndrome (RDS): Uncovering the Interactions of Maternal Health, Environmental metal pollutants, and Sociodemographic Factors
Authors: Ibrahimou Boubakari , Burchfield Shelbie , Sun Ning 
Published: January 2025

Abstract

Objective
To assess factors influencing Neonatal Respiratory Distress Syndrome (RDS) risk, incorporating maternal demographics, behaviors, medical conditions, pregnancy-related factors, and PM2.5 speciation pollutants exposures.

Methods
Using Florida de-identified birth records, logistic regression analyses were conducted to assess associations between maternal exposure to PM2.5 speciation metals during pregnancy and the risk of RDS, adjusting for various covariates.

Results
Our findings highlight the multifaceted nature of RDS risk, reaffirming known risk factors such as preterm birth, low birth weight, and maternal health conditions. Complex interactions among pollutants and maternal health factors were observed, emphasizing the importance of considering synergistic effects in risk assessment. Additionally, race and ethnicity were identified as significant factors, with nuances observed within Hispanic subgroups.

Conclusion
Targeted interventions aimed at reducing exposure to harmful pollutants, particularly among high-risk populations, may help mitigate RDS burden.
Angiotensin-Receptor Blockers Prevent Vestibular Schwannoma–Associated Hearing Loss
Authors: Early Samuel , Brown Alyssa , Xu Lei , Stankovic Konstantina M. 
Published: January 2025

Background & Introduction
Vestibular schwannoma (VS) tumors typically present with sensorineural hearing loss (SNHL). Losartan has recently demonstrated prevention of tumor-associated SNHL in a mouse model of VS through suppression of inflammatory and pro-fibrotic factors, and the current study investigates this association in humans.

Methods
This is a retrospective study of patients with unilateral VS and hypertension followed with sequential audiometry at a tertiary referral hospital from January 1994 to June 2023. Patients were stratified into subgroups by anti-hypertensive medication class. SNHL progression was assessed using Kaplan–Meier analysis to account for variable follow-up times.

Results
Two hundred thirty-six patients were identified with diagnosis of both VS and hypertension, and with sequential audiometry. Of these, 186 were taking anti-hypertensive therapy at the time of initial VS diagnosis, and 23 were taking losartan or another angiotensin receptor blocker (ARB). Patients taking an ARB were both more likely to have normal baseline hearing and no progressive hearing loss with 36.5 total patient-years of follow-up. Patients taking other anti-hypertensives all showed expected declines in hearing consistent with natural history of VS tumors.

Discussion & Conclusion
This study represents the first statistically significant association between ARB intake and hearing preservation in a real-world VS patient population. Significant confounding factors, such as concomitant hypertension in these patients, could still cloud the full effect of ARB medications' interaction with SNHL progression. Given that ARBs are well tolerated and safe, the results advocate for a prospective clinical trial to validate this effect.
The Association of Modified 5-Item Frailty Index on Perioperative Cochlear Implant Speech Perception
Authors: Fenton David , Dimitroyannis Rose , Nordgren Rachel , Asfour Nour , Sevier Joshua , Imbery Terence 
Published: January 2025

Objective
This study aims to evaluate the potential association of perioperative hearing outcomes with frailty by Modified 5-Item Frailty Index (mFI-5).

Design
Retrospective cross-sectional study.

Setting
Single-institutional study conducted at a tertiary care hospital between January 2018 and January 2022.

Patients
All adult patients older than 50 years who underwent cochlear implantation (CI).

Interventions
Cochlear implantation.

Main Outcomes Measures
Hearing outcomes were measured using pre-CI and longitudinal post-CI quiet AzBio scores. Frailty was determined by mFI-5 scores (0 = not frail, 1 = prefrail, and 2+ = frail). Univariable and multivariable linear regressions, ordinal logistic regressions, and time-to-event curves were used to determine perioperative speech perception and likelihood of high-performance hearing (defined as ≥70% on AzBio).

Results
Of the 126 patients, the median age was 70 (63–77) years, 50% (63) were female, and 39% (49) identified as non-Hispanic Black, Hispanic, or other. By mFI-5 scoring, 38% (48) had no frailty, with 34% (43) and 28% (35) scoring 1 and 2+, respectively. When adjusting for age, sex, race, and BMI, scoring 1 point on mFI-5 was associated with significantly lower pre-implantation and post-implantation AzBio scores (pre: = −15 [−26, −3.4], p < 0.05; post: = −14 [−25, −3.0], p < 0.05). When controlling for all covariates, prefrailty and frailty were associated with significantly decreased likelihood of high-performance hearing (prefrailty OR: 0.22 [0.07, 0.63], p < 0.01; frailty OR: 0.31 [0.10, 0.92], p < 0.05). Time-to-event curves demonstrate significantly reduced likelihood of reaching high-performance hearing within 7 months after CI in patients with mFI-5 scores >0 (p < 0.05).

Conclusion and Relevance
Our findings suggest that prefrailty is associated with worse pre-CI and post-CI hearing and lower likelihood of high-performance hearing within 7 months post-CI. Preoperative frailty screening in adult CI candidates may better inform providers of patients' long-term risk-to-benefit.
Impact of the COVID-19 pandemic on the mental health of Nursing students: A systematic review and meta-analysis
Authors: Badillo-Sánchez Nadine , Gómez-Salgado Juan , Allande-Cussó Regina , Yildirim Murat , López-López Daniel , Goniewicz Krzysztof , Prieto-Callejero Blanca , Fagundo-Rivera Javier 
Published: January 2025

Background:
There is an increased prevalence of mental health problems in various population groups as a result of the COVID-19 pandemic and its consequences, especially regarding anxiety, stress, depression, fear, and sleep disturbances, require to be investigated longitudinally.

Objective:
This study aimed to determine the impact that the COVID-19 pandemic had on the mental health of Nursing students, as well as to examine other associated factors such as anxiety, fear, sleep disturbances, and coping strategies.

Method:
This systematic review and meta-analysis were designed following the PRISMA guidelines and were registered in PROSPERO with code CRD42024541904. PubMed, Web of Science, CINAHL, and Scopus electronic databases were utilized. Keywords indexed in the MeSH thesaurus were used (COVID-19, nurs* student and mental health), following the Condition Context Population (CoCoPop) strategy. A total of 3866 studies were obtained of which 36 were selected for inclusion in the review. The Joanna Briggs Institute critical appraisal tool was used to assess the methodological quality of the selected studies, all of which were cross-sectional, finally including those with a cutoff point equal to or greater than 4 out of 8.

Results:
The prevalence of total anxiety was found to be 33.6% in the meta-analysis. For depression, the prevalence was 37.92%, and for stress, it was 52.46%. The results of this study show increased levels of stress, anxiety, depression, fear, and sleep disturbances among Nursing students that coincide with the different waves of the pandemic, changes in the study methodology, and the increase or decrease in reports of cases of infection. A relationship is observed between variations in these variables and the implementation of protective measures and vaccinations in different countries.

Conclusion:
As the pandemic progressed, hygiene and prevention measures became more effective, and the lethality of the virus decreased. The prevalence of the negative psychological effects also decreased from the onset in 2020 until the end of 2022. Due to the impact of the pandemic on global health, preventive measures should include personal, family, emotional, economic, educational, professional, and mental health approaches.
The effect of 4-phenylbutyrate and sodium 4-phenylbutyrate on genetic mutation diseases: A meta-analysis
Authors: Tang Wen , Cai Dihui , Song Yongfei , Liao Zufang , Lian Jiangfang 
Published: January 2025

Background:
To determine the efficacy of 4-phenylbutyrate (4-PB) or sodium 4-phenylbutyrate (SPB) in treating diseases caused by genetic mutations.

Methods:
We searched PubMed, Web of Science, Cochrane Library, and EMBASE for studies of patients with genetic mutations treated with 4-PB or SPB. All data were tested using RStudio software.

Results:
4-PB or SPB corrected the “functional” production of mutant genes (0.88 [95% confidence interval {CI}: 0.73–1.00], P = .45, I
2 = 0%), restored mRNA transcription of mutant genes (0.50 [95% CI: 0.18–0.82], P = .13, I² = 47%), and improved symptoms (0.89 [95% CI: 0.78–1.00], P = .99, I² = 0%) and biochemical laboratory values (1.00 [95% CI: 0.89–1.00], P = .11, I² = 33%) in patients with inherited genetic diseases.

Conclusion:
4-PB or SPB can be used to treat genetic diseases. However, they must be validated in high-quality randomized controlled trials before clinical use.