bluuebunny/crossref_metadata_2025_split huggingface dataset:
WALLABY pilot survey: the potential polar ring galaxies NGC 4632 and NGC 6156
Authors: Deg N , Palleske R , Spekkens K , Wang J , Jarrett T , English J , Lin X , Yeung J , Mould J R , Catinella B , Dénes H , Elagali A , For B -Q , Kamphuis P , Koribalski B S , Lee-Waddell K , Murugeshan C , Oh S , Rhee J , Serra P , Westmeier T , Wong O I , Bekki K , Bosma A , Carignan C , Holwerda B W , Yu N 
Published: September 2023

ABSTRACT
We report on the discovery of two potential polar ring galaxies (PRGs) in the WALLABY Pilot Data Release 1 (PDR1). These untargeted detections, cross-matched to NGC 4632 and NGC 6156, are some of the first galaxies where the H i observations show two distinct components. We used the iDaVIE virtual reality software to separate the anomalous gas from the galactic gas and found that the anomalous gas comprises ∼50 per cent of the total H i content of both systems. We have generated plausible 3D kinematic models for each galaxy, assuming that the rings are circular and inclined at 90° to the galaxy bodies. These models show that the data are consistent with PRGs but do not definitively prove that the galaxies are PRGs. By projecting these models at different combinations of main disc inclinations, ring orientations, and angular resolutions in mock data cubes, we have further investigated the detectability of similar PRGs in WALLABY. Assuming that these galaxies are indeed PRGs, the detectability fraction, combined with the size distribution of WALLABY PDR1 galaxies, implies an incidence rate of ∼1–3 per cent. If this rate holds true, the WALLABY survey will detect hundreds of new polar ring galaxies.
The first mm detection of a neutron star high-mass X-ray binary
Authors: van den Eijnden J , Sidoli L , Díaz Trigo M , Degenaar N , El Mellah I , Fürst F , Grinberg V , Kretschmar P , Martínez-Núñez S , Miller-Jones J C A , Postnov K , Russell T D 
Published: September 2023

ABSTRACT
Neutron stars accreting from OB supergiants are often divided between persistently and transiently accreting systems, called supergiant X-ray binaries (SgXBs) and supergiant fast X-ray transients (SFXTs). This dichotomy in accretion behaviour is typically attributed to systematic differences in the massive stellar wind, binary orbit, or magnetic field configuration, but direct observational evidence for these hypotheses remains sparse. To investigate their stellar winds, we present the results of pilot 100-GHz observations of one SFXT and one SgXB with the Northern Extended Millimetre Array. The SFXT, IGR J18410-0535, is detected as a point source at 63.4 ± 9.6 μJy, while the SgXB, IGR J18410-0535 remains undetected. Radio observations of IGR J18410-0535 imply a flat or inverted low-frequency spectrum, arguing for wind emission and against non-thermal flaring. Due to the uncertain SFXT distance, however, the observations do not necessarily imply a difference between the wind properties of the SFXT and SgXB. We compare the mm constraints with other HMXBs and isolated OB supergiants, before considering how future mm campaigns can constrain HMXB wind properties by including X-ray measurements. Specifically, we discuss caveats and future steps to successfully measure wind mass-loss rates and velocities in HMXBs with coordinated mm, radio, and X-ray campaigns.
CRISPR screens in sister chromatid cohesion defective cells reveal PAXIP1-PAGR1 as regulator of chromatin association of cohesin
Authors: van Schie Janne J M , de Lint Klaas , Molenaar Thom M , Moronta Gines Macarena , Balk Jesper A , Rooimans Martin A , Roohollahi Khashayar , Pai Govind M , Borghuis Lauri , Ramadhin Anisha R , Corazza Francesco , Dorsman Josephine C , Wendt Kerstin S , Wolthuis Rob M F , de Lange Job 
Published: September 2023

AbstractThe cohesin complex regulates higher order chromosome architecture through maintaining sister chromatid cohesion and folding chromatin by DNA loop extrusion. Impaired cohesin function underlies a heterogeneous group of genetic syndromes and is associated with cancer. Here, we mapped the genetic dependencies of human cell lines defective of cohesion regulators DDX11 and ESCO2. The obtained synthetic lethality networks are strongly enriched for genes involved in DNA replication and mitosis and support the existence of parallel sister chromatid cohesion establishment pathways. Among the hits, we identify the chromatin binding, BRCT-domain containing protein PAXIP1 as a novel cohesin regulator. Depletion of PAXIP1 severely aggravates cohesion defects in ESCO2 mutant cells, leading to mitotic cell death. PAXIP1 promotes global chromatin association of cohesin, independent of DNA replication, a function that cannot be explained by indirect effects of PAXIP1 on transcription or DNA repair. Cohesin regulation by PAXIP1 requires its binding partner PAGR1 and a conserved FDF motif in PAGR1. PAXIP1 co-localizes with cohesin on multiple genomic loci, including active gene promoters and enhancers. Possibly, this newly identified role of PAXIP1-PAGR1 in regulating cohesin occupancy on chromatin is also relevant for previously described functions of PAXIP1 in transcription, immune cell maturation and DNA repair.
The evolutionary origins of the Global Neuronal Workspace in vertebrates
Authors: Zacks Oryan , Jablonka Eva 
Published: September 2023

Abstract
The Global Neuronal Workspace theory of consciousness offers an explicit functional architecture that relates consciousness to cognitive abilities such as perception, attention, memory, and evaluation. We show that the functional architecture of the Global Neuronal Workspace, which is based mainly on human studies, corresponds to the cognitive-affective architecture proposed by the Unlimited Associative Learning theory that describes minimal consciousness. However, we suggest that when applied to basal vertebrates, both models require important modifications to accommodate what has been learned about the evolution of the vertebrate brain. Most importantly, comparative studies suggest that in basal vertebrates, the Global Neuronal Workspace is instantiated by the event memory system found in the hippocampal homolog. This proposal has testable predictions and implications for understanding hippocampal and cortical functions, the evolutionary relations between memory and consciousness, and the evolution of unified perception.
The Association Between the License Fee Increase and the Density of Tobacco Retailers in California—A Segmented Interrupted Time-Series Analysis by Income and Race/Ethnicity
Authors: He Yanyun , Yang Qian , Lu Bo , Shang Ce 
Published: September 2023

Abstract

Introduction
On May 9, 2016, the State of California passed a law to increase the licensing fee for tobacco retailers from a one-time-only fee of $100 to an annual fee of $265, effective on June 9, 2016. This study investigates the association between this fee increase and retailer densities by neighborhood income and race/ethnicity characteristics.

Methods
We obtained quarterly data on the number of active tobacco retailer licenses from 2011 to 2020 in every zip code in California from the California Department of Tax and Fee Administration. These data were then linked to zip code-level income, race/ethnicity, and population measures. We used a single-group segmented interrupted time-series analysis to assess the association between the increase in licensing fees and retailer densities by neighborhood income and race/ethnicity.

Results
After the implementation of the annual licensing fees, the retailer density decreased both immediately and gradually. Specifically, the retailer density dropped by 0.47 in the first quarter following the intervention. Compared to the pre-intervention time trend, the retailer density decreased quarterly by 0.05. Furthermore, the impacts of increasing licensing fees were more pronounced in low-income and the majority Black zip codes.

Conclusions
Given that higher smoking prevalence is associated with greater tobacco outlet density, the licensing fee increase could be an effective policy tool to reduce tobacco use among economically disadvantaged and minority Black communities, thereby addressing tobacco-use disparities.

Implications
This study used the single-group segmented interrupted time-series analysis to assess the association between the licensing fee increase and tobacco retailer densities by neighborhood income and race/ethnicity. We found that this licensing fee increase was associated with reduced retailer densities and the total number of active retailers right after the implementation. We further found that the annual licensing fee policy had a continuous effect in reducing tobacco retailer densities in all zip codes. The impacts of increasing licensing fees were more pronounced in low-income and majority of Black zip codes.
Revisiting planetary systems in the Okayama Planet Search Program: A new long-period planet, RV astrometry joint analysis, and a multiplicity-metallicity trend around evolved stars
Authors: Teng Huan-Yu , Sato Bun’ei , Kuzuhara Masayuki , Takarada Takuya , Omiya Masashi , Harakawa Hiroki , Izumiura Hideyuki , Kambe Eiji , Yilmaz Mesut , Bikmaev Ilfan , Selam Selim O , Brandt Timothy D , Xiao Guang-Yao , Yoshida Michitoshi , Itoh Yoichi , Ando Hiroyasu , Kokubo Eiichiro , Ida Shigeru 
Published: September 2023

Abstract
In this study, we revisit 32 planetary systems around evolved stars observed within the framework of the Okayama Planet Search Program (OPSP) and its collaborative framework of the East Asian Planet Search Network to search for additional companions and investigate the properties of stars and giant planets in multiple-planet systems. With our latest radial velocities obtained from Okayama Astrophysical Observatory, we confirm an additional giant planet in the wide orbit of the 75 Cet system ($P_{\rm {c}} = 2051.62_{-40.47}^{+45.98}\ \rm {d}$, $M_{\rm {c}}\sin i=0.912_{-0.090}^{+0.088}\,\,M_{\rm {J}}$, and $a_{\rm {c}}=3.929_{-0.058}^{+0.052}\ \rm {au}$), along with five stars exhibiting long-term radial velocity accelerations, which indicates massive companions in the wide orbits. We also find that the radial velocity variations of several planet-harboring stars may indicate additional planet candidates, stellar activities, or other understudied sources. These stars include ϵ Tau, 11 Com, 24 Boo, 41 Lyn, 14 And, HD 32518, and ω Ser. We further constrain the orbital configuration of the HD 5608, HD 14067, HD 120084, and HD 175679 systems by combining radial velocities with astrometry, as their host central stars exhibit significant astrometric accelerations. For other systems, we simply refine their orbital parameters. Moreover, our study indicates that the OPSP planet-harboring stars are more metal poor compared to the currently known planet-harboring stars, and this is likely due to the B − V color upper limit at 1.0 for star selection in the beginning of the survey. Finally, by investigating the less massive giant planets (&lt;5 MJ) around currently known planet-harboring evolved stars, we find that metallicity positively correlates with the multiplicity and total planet mass of the system, which can be evidence for the core-accretion planet formation model.
Newly identified lineages of porcine hemagglutinating encephalomyelitis virus exhibit respiratory phenotype
Authors: He Wan-Ting , Li Dongyan , Baele Guy , Zhao Jin , Jiang Zhiwen , Ji Xiang , Veit Michael , Suchard Marc A , Holmes Edward C , Lemey Philippe , Boni Maciej F , Su Shuo 
Published: September 2023

Abstract
Swine pathogens have a long history of zoonotic transmission to humans, occasionally leading to sustained outbreaks or pandemics. Through a retrospective epidemiological study of swine populations in China, we describe novel lineages of porcine hemagglutinating encephalomyelitis virus (PHEV) complex coronaviruses (CoVs) that cause exclusively respiratory symptoms with no signs of the neurological symptoms typically associated with classical PHEV infection. Through large-scale epidemiological surveillance, we show that these novel lineages have circulated in at least eight provinces in southeastern China. Phylogenetic and recombination analyses of twenty-four genomes identified two major viral lineages causing respiratory symptoms with extensive recombination within them, between them, and between classical PHEV and the novel respiratory variant PHEV (rvPHEV) lineages. Divergence times among the sampled lineages in the PHEV virus complex date back to 1886–1958 (mean estimate 1928), with the two major rvPHEV lineages separating approximately 20 years later. Many rvPHEV viruses show amino acid substitutions at the carbohydrate-binding site of hemagglutinin esterase (HE) and/or have lost the cysteine required for HE dimerization. This resembles the early adaptation of human CoVs, where HE lost its hemagglutination ability to adapt to growth in the human respiratory tract. Our study represents the first report of the evolutionary history of rvPHEV circulating in swine and highlights the importance of characterizing CoV diversity and recombination in swine to identify pathogens with outbreak potential that could threaten swine farming.
Aging Workforce in the Context of Technological Advancements: Toward a Socio-Ecological Model
Authors: Chang Chu-Hsiang , Xu Heng , Xie Bo 
Published: September 2023

AbstractTechnological advancements continue to result in fundamental changes to the work itself and the workplace. Although these changes can create challenges for older workers, older workers can draw from individual and contextual resources to maintain and enhance their wellbeing, motivation, and capacities, and thus achieving successful aging at work. These articles in this special issue characterize the different psychological mechanisms underlying workers’ responses to technological changes in the workplace, such as automation, digitization, and use of information and communications technologies. Integrating the findings from these articles, along with the existing theoretical models of successful aging at work, we propose a socio-ecological approach to guide future research on older workers’ adaptation to technological changes.
Differential regulation of MAP2 by phosphorylation events in proline‐rich versus C‐terminal domains
Authors: DeGiosio R. A. , Needham P. G. , Andrews O. A. , Tristan H. , Grubisha M. J. , Brodsky J. L. , Camacho C. , Sweet R. A. 
Published: September 2023

AbstractMAP2 is a critical cytoskeletal regulator in neurons. The phosphorylation of MAP2 (MAP2‐P) is well known to regulate core functions of MAP2, including microtubule (MT)/actin binding and facilitation of tubulin polymerization. However, site‐specific studies of MAP2‐P function in regions outside of the MT‐binding domain (MTBD) are lacking. We previously identified a set of MAP2 phosphopeptides which are differentially expressed and predominantly increased in the cortex of individuals with schizophrenia relative to nonpsychiatric comparison subjects. The phosphopeptides originated not from the MTBD, but from the flanking proline‐rich and C‐terminal domains of MAP2. We sought to understand the contribution of MAP2‐P at these sites on MAP2 function. To this end, we isolated a series of phosphomimetic MAP2C constructs and subjected them to cell‐free tubulin polymerization, MT‐binding, actin‐binding, and actin polymerization assays. A subset of MAP2‐P events significantly impaired these functions, with the two domains displaying different patterns of MAP2 regulation: proline‐rich domain mutants T293E and T300E impaired MT assembly and actin‐binding affinity but did not affect MT‐binding, while C‐terminal domain mutants S426E and S439D impaired all three functions. S443D also impaired MT assembly with minimal effects on MT‐ or actin‐binding. Using heterologous cells, we also found that S426E but not T293E had a lower capability for process formation than the wild‐type protein. These findings demonstrate the functional utility of MAP2‐P in the proline‐rich and C‐terminal domains and point to distinct, domain‐dependent regulations of MAP2 function, which can go on to affect cellular morphology.
Postoperative Oral Rehydration and Regimented Follow-up Decrease Readmissions for Colorectal Surgery Patients with Ileostomies
Authors: Westfall Kristen M. , Rivard Samantha J. , Suwanabol Pasithorn A. , Albright Jeremy , Ramm Carole , Cleary Robert K. 
Published: September 2023

BACKGROUND:
Ileostomies constitute 15-43% of readmissions after colorectal surgery, often due to dehydration and acute kidney injury. Prior institutional interventions decreased readmissions but not among patients with new ileostomies.

OBJECTIVE:
Evaluate readmissions among patients with new ileostomies following postoperative oral rehydration solution and standardized clinic visits.

DESIGN:
Retrospective analysis of prospective database.

SETTINGS:
Enhanced recovery colorectal surgery service.

PATIENTS:
New ileostomy patients before and after intervention.

INTERVENTION(S):
Postoperative oral rehydration solution and postdischarge clinic visits with review of inputs/outputs, antimotility and appliance needs, and trained nurse re-education 4-7 days after discharge, 30-days postoperatively, and every 1-2 weeks thereafter as needed.

MAIN OUTCOME MEASURES:
Readmission rate due to dehydration/acute kidney injury (primary), emergency department and readmission rates overall and for specific diagnoses. Analysis used univariate and weighted techniques.

RESULTS:
A total of 312 patients (199 pre-intervention; 113 post-intervention) were included, with a mean age of 59.0 years. Patients were predominantly white (94.9%) and evenly split between men and women. Most common diagnosis was diverticulitis (43.3%). Most common procedure was high anterior resection (38.8%) followed by low anterior resection (16.35%). Patient and procedure characteristics were well matched between groups. Multivariate analysis demonstrated that readmission rate due to dehydration/acute kidney injury significantly decreased between pre- and post-intervention study groups (45.7% vs 16.5%, p = 0.039). ED visits due to dehydration/acute kidney injury (12.0% vs 1.7%, p < 0.001) and readmissions from all causes (24.33% vs 10.6%, p = 0.005) also significantly decreased. Other complications were not significantly different between groups. Average stoma output 24-hours before (776 mL vs 625 mL, p = 0.005) and after (993 mL vs 890 mL, p = 0.025) discharge was significantly decreased in the post-intervention group.

LIMITATIONS:
Retrospective single center study.

CONCLUSIONS:
An oral rehydration solution and frequent standardized post-discharge visits led by trained nursing staff decreased readmissions and emergency department visits among patients with new ileostomies following colorectal surgery.
Applying the Common-Sense Self-Regulation Model to Understand Illness Representations of Mild Traumatic Brain Injury in College Students
Authors: Kemp Amy M. , Neese Madison , Norton Gabriella , O'Brien Katy H. 
Published: September 2023

Objective:
The Common Sense Model (CSM) describes cognitive, emotional, and psychosocial factors that influence how health threats are processed and subsequently inform health-related decisions or actions. The purpose of this study was to examine psychosocial factors influencing coherence, or usefulness, of mild traumatic brain injury (mTBI) representations and their relationship to health-related decisions and actions.

Setting:
Public university.

Participants:
There were 458 graduate and undergraduate college students who participated in a web-based survey (mean age = 22 years; SD = 3.6).

Design:
A mixed-methods design randomized participants into 2 groups to examine perceptions of mTBI across differing injury mechanisms, or causes, by comparing actions recommended to a friend (Other; n = 214) with those generated for self (Self; n = 244).

Main Measures:
Seven common injury mechanisms representative of university student mTBI experiences were presented as vignettes (cause). Each vignette included open- and closed-ended questions framed from CSM constructs (identity, consequences, action plans, timeline, and social context). Data were analyzed using a series of chi-square tests and multiple analysis of variance. Post hoc analysis identified differences in the injury vignettes.

Results:
Students were more likely to identify the injury as mTBI (

= 8.62, P = .035) and recommend immediate healthcare (F
1,415 = 316.89, P < .001) for all causes if the injury occurred to a friend as compared with themselves. Action plans also varied by cause, with post hoc analysis revealing a higher likelihood of healthcare seeking for motor vehicle crashes and assault and a lower likelihood for falls while intoxicated. Students were generally more likely to talk to closest confidants than doctors (F
8,398 = 33.66, P < .001).

Conclusion:
Cause appears to be a key construct in generating illness representations and associated action plans for seeking care, with lower perceived severity causes (eg, falls) resulting in little to no health-seeking action. In addition, social support appears to be important for college students when making decisions about their health.
Associations Between Traumatic Brain Injury and Severity of Tinnitus-Related Functional Impairment Among US Military Veterans: A National, Population-Based Study
Authors: Coco Laura , Hooker Elizabeth R. , Gilbert Tess A. , Prewitt Austin L. , Reavis Kelly M. , O'Neil Maya E. , Clark Khaya D. , Henry James A. , Zaugg Tara , Carlson Kathleen F. 
Published: September 2023

Objective:
To describe associations between a history of traumatic brain injury (TBI) and the severity of tinnitus-related functional impairment among a national, stratified random sample of veterans diagnosed with tinnitus by the Department of Veterans Affairs (VA) healthcare system.

Setting:
A multimodal (mailed and internet) survey administered in 2018. Participants: VA healthcare-using veterans diagnosed with tinnitus; veterans with comorbid TBI diagnosis were oversampled.

Design:
A population-based survey.

Main Measures:
TBI history was assessed using International Classification of Diseases (ICD) diagnosis codes in veterans' VA electronic health records. The severity of participants' overall tinnitus-related functional impairment was measured using the Tinnitus Functional Index. Population prevalence and 95% confidence intervals (CIs) were estimated using inverse probability weights accounting for sample stratification and survey nonresponse. Veterans' relative risk ratios of very severe or moderate/severe tinnitus-related functional impairment, versus none/mild impairment, were estimated by TBI history using bivariable and multivariable multinomial logistic regression.

Results:
The population prevalence of TBI was 5.6% (95% CI: 4.8-6.4) among veterans diagnosed with tinnitus. Veterans with a TBI diagnosis, compared with those without a TBI diagnosis, had 3.6 times greater likelihood of rating their tinnitus-related impairment as very severe (95% CI: 2.1-6.3), and 1.5 times greater likelihood of rating their impairment as moderate/severe (95% CI: 1.0-2.4), versus none/mild.

Conclusions:
These findings suggest an important role of TBI in the severity of tinnitus-related functional impairment among veterans. This knowledge can help inform the integration of tinnitus management services into the care received by veterans with TBI.