bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluating cognitive analytic therapy within a primary care psychological therapy service
Authors: Owen Kiri , Laphan Andrew , Gee Brioney , Lince Karen 
Published: June 2023

AbstractObjectivesCognitive analytic therapy (CAT) is used within UK mental health settings as a treatment for transdiagnostic complex psychological presentations. However, it is not routinely offered by the NHS Talking Therapies, for anxiety and depression (NHS Talking Therapies) programme which provides psychological treatments for common mental health difficulties. We aimed to evaluate the outcomes of providing CAT treatment to patients presenting with depression and/or anxiety, within the context of relational difficulties, adverse childhood experience or difficulty managing emotions, returning for further psychological treatment within NHS Talking Therapies.MethodsThis was a pragmatic, real‐world evaluation, involving routinely collected self‐report measures of depression and anxiety, to examine the treatment outcomes of NHS Talking Therapies patients offered CAT over an 18‐month period. Quantitative validated measures of depression and anxiety were administered at the beginning and end of CAT treatment, and at follow up. Within‐group change in depression and anxiety scores were examined statistically, and rates of reliable improvement and recovery calculated.ResultsStatistically significant decreases in depression and anxiety scores were observed during the CAT active treatment phase. The recovery rate was 46.4%, and 71.4% of patients showed a reliable improvement post‐treatment. Positive outcomes continued to be observed at follow‐up, with a recovery rate of 50% and a reliable improvement rate of 79.4%.ConclusionsCAT shows promise as a treatment option for NHS Talking Therapies patients re‐presenting with depression and/or anxiety. More research is required to determine if CAT should be offered more widely within NHS Talking Therapies services.
Transsinusoidal lateral nasal floor augmentation for implant placement in the atrophic premaxilla: A within‐patient, 5‐year, prospective comparative study
Authors: Krennmair Gerald , Weinländer Michael , Forstner Thomas , Krennmair Stefan , Stimmelmayr Michael , Malek Michael 
Published: June 2023

AbstractObjectivesTo evaluate the clinical outcome for implants placed with transsinusoidal‐lateral nasal cavity augmentation (NA) compared to implants placed in maxillary sinus augmentation (SA).Materials and MethodsIn 28 atrophic edentulous maxillary regions (14 patients bi‐maxillary), a lateral window approach was used to perform transsinusoidal‐lateral NA (TSLNA) combined with maxillary SA. After healing period of about 6 months, each patient received bimaxillary one anterior implant located in the pre‐maxilla having lateral NA and 2–3 implants in the maxillary posterior region with SA. In a prospective follow‐up evaluation, clinical implant outcome (survival/success rates) and peri‐implant health (mucositis/peri‐implantitis) were assessed and compared between implants placed in TSLNA (n = 28) and SA (n = 58).ResultsAt the year‐1, year‐3, and year‐5 evaluation, neither patient‐based nor implant‐based comparisons revealed differences for marginal bone level reduction between implants placed in TSLNA (5‐year overall: 1.11 ± 0.26 mm) and SA (5‐year overall: 1.07 ± 0.30 mm), although with a significant (p < .001) continuous reduction over the observation time. At the year‐5 evaluation, all implants (n = 86) and restorations (n = 14) were still in situ (survival 100%) and showed an implant‐based incidence of peri‐implant mucositis/peri‐implantitis of 14.3%/0% in TSLNA and 6.9%/3.4% in SA corresponding to 21.4%/0% and 28.6%/7.1% for implant‐based evaluation. In addition, the implant success rate did not differ between NA and SA at implant‐ (100%/ 98.8%) and patient‐based (100%/97.6%) evaluation.ConclusionThe findings obtained show TSLNA as an effective method for implant placement of adequate length and direction in the atrophic premaxilla providing for success rates comparable to those of implants placed in SA.
Discontinuity of marginal artery at splenic flexure and rectosigmoid junction: A systematic review and meta‐analysis
Authors: Cirocchi Roberto , Randolph Justus , Cheruiyot Isaac , Davies R. Justin , Gioia Sara , Henry Brandon Michael , Anania Gabriele , Donini Annibale , Mingoli Andrea , Sapienza Paolo , Avenia Stefano 
Published: June 2023

AbstractAimThe aim of this study was to provide comprehensive evidence‐based assessment of the discontinuity of the marginal artery at the splenic flexure (SF) and the rectosigmoid junction (RSJ).MethodA systematic review was conducted of literature published to 26 December 2022 in the electronic databases PubMed, SCOPUS and Web of Science to identify studies eligible for inclusion. Data were extracted and pooled into a meta‐analysis using the Metafor package in R. The primary outcomes were the pooled PPEs of the marginal artery at the SF and the RSJ. The secondary outcome was the size of vascular anastomoses.ResultsA total of 21 studies (n = 2,864 patients) were included. The marginal artery was present at the splenic flexure in 82% (95% CI: 62–95) of patients. Approximately 81% (95% CI: 63–94%) of patients had a large macroscopic anastomosis, while the remainder (19%) had small bridging ramifications forming the vessel. The marginal artery was present at the RSJ in 82% (95% CI: 70–91%) of patients.ConclusionThe marginal artery may be absent at the SF and the RSJ in up to 18% of individuals, which may confer a higher risk of ischaemic colitis. As a result of high interstudy heterogeneity noted in our analysis, further well‐powered studies to clarify the prevalence of the marginal artery at the SF and the RSJ, as well as its relationship with other complementary colonic collaterals (intermediate and central mesenteric), are warranted.
Survival in relation to time to start of curative treatment of colon cancer: A national register‐based observational noninferiority study
Authors: Rydbeck Daniel , Bock David , Haglind Eva , Angenete Eva , Onerup Aron 
Published: June 2023

AbstractAimThere are ample discussions regarding the timing of treatment, especially in the era after Covid that caused delay to treatment. The aim of this study was to determine whether a delayed start to curative treatment, within 29–56 days after a diagnosis of colon cancer, was noninferior to starting treatment within 28 days, with regard to all‐cause mortality.MethodThis is a national register‐based observational noninferiority study, with a noninferiority margin of hazard ratio (HR) 1.1, including all patients treated with curative intent for colon cancer in Sweden between 2008 and 2016. The primary outcome was all‐cause mortality. Secondary outcomes were length of hospital stay, readmissions and reoperations within 1 year after surgery. Exclusion criteria were emergency surgery, disseminated disease at diagnosis, missing diagnosis date and treatment for another cancer 5 years before colon cancer diagnosis.ResultsA total of 20 836 individuals were included. A period of 29–56 days from diagnosis to start of curative treatment was noninferior versus starting treatment within 28 days for the primary outcome of all‐cause mortality (HR 0.95, 95% CI 0.89–1.00). Starting treatment within 29–56 days was associated with a shorter length of stay (average 9.2 vs. 10 days) but a higher risk of reoperation compared to within 28 days. Post hoc analyses demonstrated that surgical modality was driving survival rather than time to treatment. Overall survival was greater after laparoscopic surgery (HR 0.78, 95% CI 0.69–0.88).ConclusionFor patients with colon cancer, a period of up to 56 days from diagnosis to the start of curative treatment did not lead to worse overall survival.
Syntheses and dyeing properties of novel water‐soluble reactive sulphur black dyes
Authors: Gao Zhengyang , Ma Wei , Tang Bingtao , Zhang Shufen 
Published: June 2023

AbstractThe practical application of a sulphur black dye relies on its ability to dye cotton fibres with pure black colour and maintain the colour with high light fastness. Here, we report a synthesis method to prepare a novel water‐soluble reactive sulphur black dye. The approach involves the reduction of CI Sulphur Black 1 to its leuco form and subsequent reaction with a water‐soluble intermediate containing reactive groups synthesised from amino acid and cyanuric chloride. The optimal carboxyl and reactive group content of the water‐soluble reactive sulphur black dye is 141 mmol/100 g, and the water solubility can reach 92 g/L. The fixation of the reactive sulphur black dye on cotton reaches 89% in a pad dyeing process without using sodium sulphate. The reactive sulphur black dye can achieve a light fastness of grade 6‐7, a dry rub fastness of grade 4 and a wet rub fastness of grade 2, comparable or higher than the conventional CI Sulphur Black 1. The dyeing results showed that the novel water‐soluble reactive sulphur black dye has excellent performance and good application prospects.
Evaluation of the prognostic value of lncRNA UCA1 combined with extravascular lung water index and lung ultrasound score in patients with acute lung injury
Authors: Jiang Zhaopeng , Wu Jiaqi , Wan Ming , Liu Lingling , Zhou Xianli 
Published: June 2023

AbstractIntroductionAcute lung injury (ALI) is a common and rapidly developing critical inflammatory lung disease in clinic. This study investigated the predictive value of lncRNA UCA1, extravascular lung water index (EVLWI), and lung ultrasound score (LUS) in predicting the overall outcome of patients with ALI.MethodsPatients with ALI were recruited for detecting the content of UCA1, EVLWI, and LUS. All patients were cataloged into the survival group and death group according to the prognosis. The discrepancy of UCA1, EVLWI, and LUS was compared in the two groups. The prognostic significance of UCA1, EVLWI, LUS, and their combination was estimated by logistic regression and the receiver operating characteristic (ROC) curve.ResultsThe levels of UCA1, LUS, and EVLWI were elevated in the death group compared with the survival group. The content of UCA1 was positively correlated with LUS scores and EVLWI scores. UCA1, LUS, and EVLWI were independent indicators of predicting the prognosis of patients with ALI. The ROC curve reflected that UCA1, LUS, and EVLWI could forecast the endpoint events of patients with ALI whereas their combined approach had the highest accuracy.ConclusionHighly expressed UCA1 is a biomarker in forecasting the outcome of patients with ALI. It had high accuracy in predicting the endpoint of patients with ALI when combined with LUS and EVLWI.
Agential autonomy and biological individuality
Authors: Fulda Fermin C. 
Published: June 2023

AbstractWhat is a biological individual? How are biological individuals individuated? How can we tell how many individuals there are in a given assemblage of biological entities? The individuation and differentiation of biological individuals are central to the scientific understanding of living beings. I propose a novel criterion of biological individuality according to which biological individuals are autonomous agents. First, I articulate an ecological–dynamical account of natural agency according to which, agency is the gross dynamical capacity of a goal‐directed system to bias its repertoire to respond to its conditions as affordances. Then, I argue that agents or agential dynamical systems can be agentially dependent on, or agentially autonomous from, other agents and that this agential dependence/autonomy can be symmetrical or asymmetrical, strong or weak. Biological individuals, I propose, are all and only those agential dynamical systems that are strongly agentially autonomous. So, to determine how many individuals there are in a given multiagent aggregate, such as multicellular organism, a colony, symbiosis, or a swarm, we first have to identify how many agential dynamical systems there are, and then what their relations of agential dependence/autonomy are. I argue that this criterion is adequate to the extent that it vindicates the paradigmatic cases, and explains why the paradigmatic cases are paradigmatic, and why the problematic cases are problematic. Finally, I argue for the importance of distinguishing between agential and causal dependence and show the relevance of agential autonomy for understanding the explanatory structure of evolutionary developmental biology.
Radial basis function networks with lightweight multiscale fusion strategy‐based underwater image enhancement
Authors: Mythili R. , bama B. Sathya , Kumar P. Santhosh , Das Sanchali , Thatikonda Ramya , Inthiyaz Syed 
Published: June 2023

AbstractA novel underwater picture enhancement approach under non‐uniform lighting is presented to solve the issues of underwater photographs with unevenness due to additional lighting in deep‐sea and night‐time environments. Water suspended particles can cause image noise, low contrast, and colour deviation. The heterogeneous feature fusion module aims to combine multiple levels and levels of features with improving the network's ability to perceive semantic and specific information. The capability of autonomous underwater and remotely driven cars to explore and comprehend their environments is contingent on improving underwater images, a crucial low‐level computer vision challenge. Recent applications of deep learning models include enhancing aquatic image quality and resolving several computer vision problems. Although several deep learning‐based techniques exist for enhancing underwater images, their implementation is challenging due to the high memory and model parameter requirements. We propose a solution based on radial basis function networks (RBFN) for lightweight multiscale data fusion (LMFS). The LMFS incorporates diverse branches with varying kernel sizes to generate multiscale feature maps. The proposed RBFN‐LMFS The convolution layer with jump connection and the attention module produces the output from the feature extraction module, which aims to extract various features at the network's beginning. The outcomes of our experiments on diverse data sets demonstrate that our proposed RBFN‐LMFS technique performs well in processing both synthetic and authentic underwater images and successfully recovers image colour and texture characteristics. The visual output is superior to existing underwater image enhancement algorithms and is consistent with aspects of human vision.
Pre‐fatigue damage on the mechanical properties of Q690D steel
Authors: Zong Liang , Liu Heng , Si Qi , Chung Kwai‐Fai 
Published: June 2023

AbstractThis article aims to analyze the influence of high‐cycle fatigue damage on the mechanical properties and low‐cycle fatigue performance of Q690D. Monotonic tensile and cyclic loading tests were performed on Q690D specimens with different degrees of high‐cycle fatigue damage. Degradation models were established to describe the declining trend of mechanical properties with the increase of pre‐fatigue damage. Manson–Coffin models for Q690D steels of different pre‐damage levels were established. Besides, a comparison was presented between Q690D and Q355B. The research work in this article provides a fundamental reference for the appropriate assessment of the mechanical performance of Q690D high‐strength steel structures after long‐term alternating loading.
Broadleaf tree phenology and springtime wildfire occurrence in boreal Canada
Authors: Parisien Marc‐André , Barber Quinn E. , Flannigan Mike D. , Jain Piyush 
Published: June 2023

AbstractAlthough broadleaf tree species of the boreal biome have a lower flammability compared to conifers, there is a period following snow melt and prior to leaf flush (i.e., greenup), termed the “spring window” by fire managers, when these forests are relatively conducive to wildfire ignition and spread. The goal of this study was to characterize the duration, timing, and fire proneness of the spring window across boreal Canada and assess the link between these phenological variables and the incidence of springtime wildfires. We used remotely sensed snow cover and greenup data to identify the annual spring window for five boreal ecozones from 2001 to 2021 and then compared seasonality of wildfire starts (by cause) and fire‐conducive weather in relation to this window, averaged over the 21‐year period. We conducted a path analysis to concomitantly evaluate the influence of the spring window's duration, the timing of greenup, and fire‐conducive weather on the annual number and the seasonality of spring wildfires. Results show that the characteristics of spring windows vary substantially from year to year and among geographic zones, with the interior west of Canada having the longest and most fire‐conducive spread window and, accordingly, the greatest springtime wildfire activity. We also provide support for the belief that springtime weather generally promotes wind‐driven, rather than drought‐driven wildfires. The path analyses show idiosyncratic behavior among ecozones, but, in general, the seasonality of the wildfire season is mainly driven by the timing of the greenup, whereas the number of spring wildfires mostly responds to the duration of the spring window and the frequency of fire‐conducive weather. The results of this study allows us to better understand and anticipate the biome‐wide changes projected for the northern forests of North America.
Niche conservatism over deep timescales and diverse niche axes in land vertebrates
Authors: Saban Kristen E. , Qu Yan‐Fu , Wiens John J. 
Published: June 2023

AbstractAimThere has been considerable interest in niche conservatism, the idea that ecological variables are similar among related species. Much research has focused on climatic niches of recently diverged species, rather than deeper timescales or non‐climatic niche axes. Furthermore, it has been suggested that conservatism disappears over deeper timescales, and is greater in alpha niche traits (like diet and microhabitat) than beta niche variables (like climate). Here, we test these latter two ideas by comparing patterns of phylogenetic conservatism among 10 niche variables across major clades of land vertebrates.LocationGlobal.Time PeriodPresent to 350 million years ago.Major Taxa StudiedTetrapods, including amphibians, mammals, lepidosaurs (including lizards and snakes), turtles, crocodilians and birds.MethodsThe 10 niche variables included four alpha niche components (diet, diel activity, habitat, body temperature) and six beta niche components (related to climatic temperature and precipitation). We analysed these variables on time‐calibrated phylogenies with similar taxon sampling (~1700 species), using phylogenetic signal (lambda) to estimate conservatism, along with the D statistic and estimates of evolutionary rates.ResultsPhylogenetic signal was generally strong across all variables, with lambda generally >0.80 (with 1.0 representing maximum signal). Nevertheless, mean phylogenetic signal was lower in beta niche traits than alpha niche traits (based on lambda and especially the D statistic), and alpha niche traits showed significantly slower rates of evolution.Main ConclusionsWe address two long‐held views in the literature on niche conservatism, rejecting one but supporting the other. We show that phylogenetic signal does not disappear over deep timescales for many important niche variables, even over 350 million years. We also generally support greater conservatism in alpha niche traits than beta niche traits over hundreds of millions of years, a pattern that was previously suggested (but not explicitly tested) based on closely related species.
Bone marrow haematopoiesis in patients with COVID‐19
Authors: Marques‐Maggio Ewerton , Maccio Umberto , Marx Alexandra , Galli Serena , Schwab Nathalie , Frank Angela , Hamelin Baptiste , Varga Zsuzsanna , Nombela‐Arrieta César , Mertz Kirsten D , Theocharides Alexandre PA , Koelzer Viktor H 
Published: June 2023

AimsSevere acute respiratory syndrome coronavirus type 2 (SARS‐CoV‐2) infection broadly affects organ homeostasis, including the haematopoietic system. Autopsy studies are a crucial tool for investigation of organ‐specific pathologies. Here we perform an in‐depth analysis of the impact of severe coronavirus disease 2019 (COVID‐19) on bone marrow haematopoiesis in correlation with clinical and laboratory parameters.Methods and resultsTwenty‐eight autopsy cases and five controls from two academic centres were included in the study. We performed a comprehensive analysis of bone marrow pathology and microenvironment features with clinical and laboratory parameters and assessed SARS‐CoV‐2 infection of the bone marrow by quantitative polymerase chain reaction (qPCR) analysis. In COVID‐19 patients, bone marrow specimens showed a left‐shifted myelopoiesis (19 of 28, 64%), increased myeloid–erythroid ratio (eight of 28, 28%), increased megakaryopoiesis (six of 28, 21%) and lymphocytosis (four of 28, 14%). Strikingly, a high proportion of COVID‐19 specimens showed erythrophagocytosis (15 of 28, 54%) and the presence of siderophages (11 of 15, 73%) compared to control cases (none of five, 0%). Clinically, erythrophagocytosis correlated with lower haemoglobin levels and was more frequently observed in patients from the second wave. Analysis of the immune environment showed a strong increase in CD68+ macrophages (16 of 28, 57%) and a borderline lymphocytosis (five of 28, 18%). The stromal microenvironment showed oedema (two of 28, 7%) and severe capillary congestion (one of 28, 4%) in isolated cases. No stromal fibrosis or microvascular thrombosis was found. While all cases had confirmed positive testing of SARS‐CoV‐2 in the respiratory system, SARS‐CoV‐2 was not detected in the bone marrow by high‐sensitivity PCR, suggesting that SARS‐CoV‐2 does not commonly replicate in the haematopoietic microenvironment.ConclusionsSARS‐CoV‐2 infection indirectly impacts the haematological compartment and the bone marrow immune environment. Erythrophagocytosis is frequent and associated with lower haemoglobin levels in patients with severe COVID‐19.
Effectiveness and safety of a narrow band spectrum intense pulsed‐light dye with long pulse Nd:YAG laser for treating facial vascular lesions
Authors: Urdiales‐Gálvez Fernando , Castellano‐Miralla Antonio 
Published: June 2023

AbstractObjectiveDifferent devices are currently used for treating facial vascular lesions (FVL). This paper presents the aesthetic outcomes using different light‐based and laser devices, including narrow band spectrum intense pulsed‐light dye (NB‐Dye‐VL), Pulsed dye laser (PDL)–neodymium‐doped yttrium‐aluminum‐garnet (Nd:YAG) dual‐therapy, and either PDL or LP Nd:YAG for treating FVL in a clinical setting.MethodsA retrospective and single‐center study conducted on subjects ≥18 years with FVL. Patients underwent treatment with either PDL + LP Nd:YAG dual‐therapy, NB‐Dye‐VL, PDL, or LP Nd:YAG, according to the patient and lesion characteristics. The primary outcome was the weighted degree of satisfaction.ResultsThe cohort consisted of fourteen patients, nine women (64.3%) and five men (35.7%). The most prevalent FVL types treated were rosacea (28.6%; 4/14) and spider hemangioma (21.4%; 3/14). Seven patients underwent PDL + Nd:YAG (50.0%), three were treated with NB‐Dye‐VL (21.4%), and PDL or LP Nd:YAG was performed in two patients each (14.3%). Eleven patients rated their treatment outcome as excellent (78.6%), and three as very good (21.4%). Practitioners 1 and 2 classified treatment results as excellent in eight cases (57.1%) each. No serious or permanent adverse events were reported. Two (14.3%) patients, one treated with PDL and the other with PDL + LP Nd:YAG dual‐therapy, had post‐treatment purpura, which was successfully resolved with topical treatment after 5 and 7 days, respectively.ConclusionsNB‐Dye‐VL and the PDL + LP Nd:YAG dual‐therapy devices achieve excellent aesthetic outcomes for treating a wide range of FVL.