bluuebunny/crossref_metadata_2025_split huggingface dataset:
iTRAQ‐based proteomic analysis reveals proteins associated with cold stress response in two different populations of Manila clam (Ruditapes philippinarum)
Authors: Xu Qiaoyue , Nie Hongtao , Dong Shasha , Song Jun , Wang Qingzhi , Yan Xiwu 
Published: January 2023

AbstractWater temperature is one of the key environmental factors for marine ectotherms and a change in temperature beyond and organism's capacity limits can cause a series of changes to physiological state and damage to the organism. Understanding how organisms adapt to complex environments is a central goal of evolutionary biology and ecology. Ruditapes philippinarum is an ecologically and scientifically important marine bivalve species. To uncover the molecular mechanisms of acclimation of R. philippinarum to low‐temperature stress, iTRAQ‐based quantitative proteomics was conducted to compare the proteomes of the north and south populations of R. philippinarum under low‐temperature stress. The results showed a total of 6355 and 6352 proteins were identified in two populations, respectively. Among these, 94 and 83 were differentially abundant proteins (DAPs), and most of DAPs were related to oxidation‐process, protein binding, or an integral component of membrane. According to the results of KEGG pathway enrichment analysis, most of DAPs in both populations are involved in immune‐related pathways, while other population‐specific significant abundance proteins of south population and north population were enriched in biosynthesis of amino acids (Enolase, Glutamine synthetase) and unsaturated fatty acids pathways (3‐ketoacyl‐CoA thiolase, Stearoyl‐CoA desaturase), respectively, indicating that two population of clams may have different cold‐stress regulation mechanisms. Our study provides new insights into different cold stress tolerance mechanisms in northern and southern populations of R. philippinarum using iTRAQ‐based proteomics. This work contributes to a better understanding of molecular basis on cold stress response and adaptations, which shed lights on evolutionary biology and general ecophysiology of R. philippinarum.
Electronic properties of carbazole/biphenylamino functionalized sulfone‐based host materials
Authors: Xu Xiaopei , Huang Zehua , Liang Xuefeng , Tang Xinyuan , Zhao Yongze , Li Huifang , He Yan , Zhang Lisheng 
Published: January 2023

AbstractSulfone‐based molecules are widely used as molecular building blocks for host materials in the emissive layers of organic light‐emitting diodes (OLEDs). In this work, the electronic properties of dibenzo[b,d]thiophene 5,5‐dioxide (DBTO) and its derivatives were investigated by quantum‐chemical techniques to get more detailed information about the carbazole and biphenylamino functionalization effects on the charge injection property and triplet transition energy of such SO2‐based host materials. Calculated results demonstrated that the charge injection property of DBTO can be tuned by different functionalization strategies. Vertical ionization potential (VIP) and vertical electron affinity (VEA) values are reduced by functionalization, especially in the case of biphenylamino substitution. The S0 → S1 and S0 → T1* transitions, which are mainly dominated by the HOMO and LUMO energy levels, can also be tuned by functionalization. For the S0 → S1 transition, the effect of carbazole substitution is larger than that of biphenylamino substitution, while the effect of carbazole substitution on the S0 → T1* transition energies of DBTO is smaller than that of biphenylamino substitution. This effect will be more obvious if the number of introduced functional groups increases. In addition, it was observed that the substitution effect at the meta‐position of DBTO is much larger than that at the para‐position.
The impact of cancer on psychosocial function and quality of life: A cross‐sectional study in 18 pan‐European countries
Authors: Bazilainsky Svetlana , Cohen Miri , Holtmaat Karen , Erlich Brach , Verdonck‐de Leeuw Irma M. 
Published: January 2023

AbstractBackgroundTo improve psychosocial cancer care in Europe, more information is needed on psychosocial function and quality of life (QoL) among cancer patients in European countries.AimsTo investigate differences in psychosocial function between cancer survivors and the general population in Europe, in relation to national economic status and personal factors.MethodData were from the Survey of Health, Aging and Retirement in Europe (Wave 6). Main outcomes were psychosocial functioning: activity limitations, income adequacy, loneliness, depression, and QoL. Factors possibly associated with the main outcomes were ever having cancer, gross domestic product (GDP), and personal factors (age, gender, education, marriage status, employment status, number of children, number of chronic diseases).ResultsThe study sample featured 6238 cancer survivors and 60,961 individuals without cancer aged 50 or older in 17 European countries and Israel. Levels of depression were higher and QoL was lower among cancer survivors compared to individuals without cancer and worse in low GDP countries, whereas differences in income adequacy and loneliness were not statistically significant. The interaction of cancer groups and country groups indicated a significant interactional effect on activity limitations, loneliness, depression, and QoL. In a multivariate regression analysis, personal factors, GDP, and being a cancer survivor predicted the main outcome variables.ConclusionsCancer has a persistent negative effect on survivors that is related to a country's GDP. Cancer survivors in low‐GDP countries are affected by the consequences of cancer intertwined with the hardships of living in a low‐GDP country.
Relationship between demoralization and quality of life in end‐of‐life cancer patients
Authors: Bovero Andrea , Opezzo Marta , Tesio Valentina 
Published: January 2023

AbstractObjectiveTo examine the relationship between demoralization and health‐related quality of life (HRQoL) in a sample of end‐of‐life cancer patients with a life expectancy of 4 months or less undergoing palliative care, controlling for sociodemographic, clinical, and psychological variables.MethodsSociodemographic, clinical, and psychological data from 170 end‐of‐life cancer patients were collected using the following scales: Edmonton Symptom Assessment System for palliative care patients' symptoms; Patient Health Questionnaire‐9 (PHQ‐9) for depressive symptoms; Functional Assessment of Cancer Therapy Scale ‐ General Measure (FACT‐G) for HRQoL; Functional Assessment of Chronic Illness Therapy ‐ Spiritual Well‐Being for spirituality (FACIT‐Sp); Demoralization Scale ‐ Italian Version (DS‐IT) for demoralization.ResultsThe DS‐IT showed that 51.8% of cancer patients were severely demoralized. In addition, 36.5% of the sample had clinically significant depressive symptoms and QoL was severely impaired (FACT‐G). The result of regression analysis showed that demoralization (especially “Disheartenment” and “Sense of failure”) was the strongest contributor for HRQoL, followed by ESAS_Lack of Well‐Being and depression (PHQ‐9), with the final model explaining 66% of the variance of the FACT‐G.ConclusionsThe results highlight a very high prevalence of severe demoralization in end‐of life cancer patients. Moreover, demoralization was not only associated with patients' HRQoL, but it was also the most important contributing factor. This finding underscores the need to identify preventive or therapeutic psychological interventions that focus on preventing existential distress, and thus improve the QoL of dying patients in their last days of life.
Holographic Complexity of Braneworld in Horndeski Gravity
Authors: Santos Fabiano F. , Sokoliuk Oleksii , Baransky Alexander 
Published: January 2023

AbstractThis work investigates the influence of a probe string on a complexity of braneworld according to the CA (Complexity equals action) conjecture within the Horndeski gravity. In the current study, it is considered that scalar fields that source Horndeski gravity have a spatial dependence. In addition, our system contains a particle moving on the boundary, which corresponds to the insertion of a fundamental string in the higher dimensional bulk. Such an effect is given by the Nambu‐Goto term, that also incorporates the time‐dependence and evolution in our system. Both warp factor, scalar field and superpotential values are derived numerically assuming appropriate initial conditions and the growth rate of holographic complexity is analysed within the so‐called Wheeler‐De Witt (WDW) patch with null‐like hypersurfaces present.
Establishing an index for monitoring occupational health and well‐being of coal mines: Consideration of individual characteristics
Authors: Zhou Xiaofeng , Zhao Xu , Sun Ninghao , Wang Dongdong , Tong Ruipeng 
Published: January 2023

AbstractIt is crucial to enhance employee occupational health and well‐being (OHW) for the well‐run and prosperity of the industry, but there is very limited knowledge on the assessment of miners' well‐being that differs from person to person. Within this study, a new more direct method, as well as an instrument was constructed to measure the OHW through data analysis based on a representative sample of coal miners (N = 1037). Initially, the causal pathway of job stress and health consequences was characterized by the driving force‐pressure‐state‐impact‐response (DPSIR) model. The OHW index was represented by hazards, vulnerability, and severity through the data envelopment analysis and stochastic frontier approach method. The result was that the severity of the consequences of inadequate organizational response was the dominant factor. 75% of employees with poor OHW work in mining, and digging areas, including various drivers and support workers. This study provides an innovative and complete description of the interaction mechanisms among job stress, job burnout, and health outcomes. It demonstrates that a three‐level assessment method, namely hazards‐vulnerability‐severity, can effectively identify hierarchical management points. We provide metrics, objective data, and evidence‐based recommendations on stress and health management for miners.
Emerging Materials and Strategies for Passive Daytime Radiative Cooling
Authors: Gao Wei , Chen Yongping 
Published: January 2023

AbstractIn recent decades, the growing demands for energy saving and accompanying heat mitigation concerns, together with the vital goal for carbon neutrality, have drawn human attention to the zero‐energy‐consumption cooling technique. Recent breakthroughs in passive daytime radiative cooling (PDRC) might be a potent approach to combat the energy crisis and environmental challenges by directly dissipating ambient heat from the Earth to the cold outer space instead of only moving the heat across the Earth's surface. Despite significant progress in cooling mechanisms, materials design, and application exploration, PDRC faces potential functionalization, durability, and commercialization challenges. Herein, emerging materials and rational strategies for PDRC devices are reviewed. First, the fundamental physics and thermodynamic concepts of PDRC are examined, followed by a discussion on several categories of PDRC devices developed to date according to their implementation mechanism and material properties. Emerging strategies for performance enhancement and specific functions of PDRC are discussed in detail. Potential applications and possible directions for designing next‐generation high‐efficiency PDRC are also discussed. It is hoped that this review will contribute to exciting advances in PDRC and aid its potential applications in various fields.
Advance of Prussian Blue‐Derived Nanohybrids in Energy Storage: Current Status and Perspective
Authors: Wang Ronghao , Qian Chengfei , Zhang Zherui , Shen Hao , Xia Jingjie , Cui Dingyu , Sun Kaiwen , Liu He , Guo Cong , Yu Feng , Li Jingfa , Bao Weizhai 
Published: January 2023

AbstractGreat changes have occurred in the energy storage area in recent years as a result of rapid economic expansion. People have conducted substantial research on sustainable energy conversion and storage systems in order to mitigate the looming energy crisis. As a result, developing energy storage materials is critical. Materials with an open frame structure are known as Prussian blue analogs (PBAs). Anode materials for oxides, sulfides, selenides, phosphides, borides, and carbides have been extensively explored as anode materials in the field of energy conversion and storage in recent years. The advantages and disadvantages of oxides, sulfides, selenides, phosphides, borides, carbides, and other elements, as well as experimental methodologies and electrochemical properties, are discussed in this work. The findings reveal that employing oxides, sulfides, selenides, phosphides, borides, and other electrode materials to overcome the problems of low conductivity, excessive material loss, and low specific volume is ineffective. Therefore, this review intends to address the issues of diverse energy storage materials by combining multiple technologies to manufacture battery materials with low cost, large capacity, and extended service life.
Immunized Microspheres Engineered Hydrogel Membrane for Reprogramming Macrophage and Mucosal Repair
Authors: Wen Xiao , Xi Kun , Tang Yu , Bian Jie , Qin Yu , Xiao Wanshu , Pan Tingzheng , Cheng Xiaoming , Ge Zili , Cui Wenguo 
Published: January 2023

AbstractThe “double‐edged sword” effect of macrophages under the influence of different microenvironments determines the outcome and prognosis of tissue injury. Accurate and stable reprogramming macrophages (Mφ) are the key to rapid wound healing. In this study, an immunized microsphere‐engineered GelMA hydrogel membrane is constructed for oral mucosa treatment. The nanoporous poly(lactide‐co‐glycolide) (PLGA) microsphere drug delivery system combined with the photo‐cross‐linkable hydrogel is used to release the soybean lecithin (SL)and IL‐4 complexes (SL/IL‐4) sustainedly. In this way, it is realized effective wound fit, improvement of drug encapsulation, and stable triphasic release of interleukin‐4 (IL‐4). In both in vivo and in vitro experiments, it is demonstrated that the hydrogel membrane can reprogram macrophages in the microenvironment into M2Mφ anti‐inflammatory types, thereby inhibiting the local excessive inflammatory response. Meanwhile, high levels of platelet‐derived growth factor (PDGF) secreted by M2Mφ macrophages enhanced neovascular maturation by 5.7‐fold, which assisted in achieving rapid healing of oral mucosa. These findings suggest that the immuno‐engineered hydrogel membrane system can re‐modulating the biological effects of Mφ, and potentiating the maturation of neovascularization, ultimately achieving the rapid repair of mucosal tissue. This new strategy is expected to be a safe and promising immunomodulatory biomimetic material for clinical translation.
KOH‐Enabled Axial‐Oxygen Coordinated Ni Single‐Atom Catalyst for Efficient Electrocatalytic CO2 Reduction
Authors: Chen Xuanyi , Liu Wei , Sun Yuxia , Tan Ting , Du Chen‐Xia , Li Yuehui 
Published: January 2023

AbstractPrecise control of the coordination structure of metal centers is an ideal approach to achieve reasonable selectivity, activity, and stability in the electrochemical reduction of CO2. In this work, the KOH activation strategy for preparation of hierarchically porous material containing Ni single‐atoms with axial‐oxygen coordination is reported. Spectroscopic measurements reveal the multiple roles of KOH as oxygen source, pore‐making reagent and promoter for the formation of key phthalocyanine structure. It exhibits superior surface area (1801 m2 g−1) and electrocatalytic performance (Faradaic efficiency of 94%, Turnover frequency of 11 362 h−1). Notably, KOH‐enabled architecture with abundant pores benefits the anchoring of Ni atoms and mass transfer for high activity and selectivity. Density functional theory calculations suggest that the axial‐oxygen ligand can promote the electronic delocalization of the Ni site for facilitating the *COOH formation and *CO desorption to efficiently produce CO.
Surgical safety checklists in UK veterinary practice: Current implementation and attitudes towards their use
Authors: Hill Jessica , Irwin‐Porter Gemma , Buckley Louise A. 
Published: January 2023

AbstractBackgroundSurgical safety checklist (SSC) use benefits veterinary patients, but endorsement and implementation are essential for these benefits to be observed.MethodsA cross‐sectional survey assessed UK veterinary professionals' attitudes towards and usage of SSCs and identified factors associated with poorer attitude or failure to use SSCs.ResultsOf 513 respondents, 70% used SSCs. Of these, 87.1% used SSCs for every surgical procedure, 19.1% adapted SSCs for different procedures and 61.1% had a standard operating procedure detailing how to use SSCs. Attitudes towards SSC use were favourable, with increased positive attitude associated with employing at least one registered veterinary nurse with a post‐qualifying qualification (p < 0.001), current SSC use (p < 0.001), undertaking self‐directed reading (p = 0.033) or completing SSC‐relevant post‐qualification continuing professional development (p = 0.005). Factors associated with veterinary practices not using SSCs included Practice Standards Scheme (PSS) non‐membership (odds ratio [OR] 2.0, 1.1–3.4), no RCVS hospital status (OR 1.9, 1.1–3.5) or being a mixed first‐opinion veterinary practice (OR 2.4, 1.2–5.0).LimitationsStudy limitations include sampling methodology and non‐validated attitudinal scale usage.ConclusionMost respondents used SSCs. Familiarity, education and the RCVS PSS were associated with improved uptake and attitudes, but mixed practice was associated with reduced usage.
A bio‐based compatibilizer for improved interfacial compatibility in thermally conductive and electrically insulating graphite/high density poly(ethylene) composites
Authors: Zhou Hua , Ye Liangdong , Chen Dongming , Li Ziwei , Li Shanrong , Li Dacheng , Huang Zhiyi , Wei Zhouqiao , Lu Shaorong 
Published: January 2023

AbstractGraphite is a thermally conductive filler. However, when dispersed into high density poly(ethylene) (HDPE) resin, graphite particles tend to agglomerate and requires a compatibilizer to achieve desired thermal/physical properties. In this study, oleic acid (OA), a bio‐based additive and polyethylene‐polyamines (PEPA) were used to synthesize a new compatibilizer, PEPA‐g‐OA, containing numerous NR2 groups. The experimental results showed that PEPA‐g‐OA can significantly improve the compatibility between graphite particles and the HDPE matrix due to uniform dispersion of graphite in the HDPE matrix. When the graphite content was 25 wt%, the thermal conductivity of the composite recorded 1.2 W m−1 K−1 (three times that of neat HDPE) and the volume resistivity was 1.8 × 109 Ω cm, indicating excellent electrical insulation. Compared to the composites with no graphite content, the properties of the composites with 25 wt% graphite content exhibited narrower melting and crystallization peaks, more stable mechanical properties, and higher ultraviolet aging resistance. Synthesized new bio‐based compatibilizer and thermally conductive and electrically insulating composites developed in this study can be useful in different industrial fields for the preparation of the next generation composites.
Wandering, twisted spleen in a deerhound
Authors: Dillberger John E. , Stephenson Betty L. 
Published: January 2023

AbstractA 14‐month‐old, entire, deerhound bitch experienced episodes of abdominal discomfort. During some episodes, the abnormally shaped spleen could be palpated in the dorsocaudal abdomen, rather than in its normal cranioventral location. Exploratory laparotomy revealed an enlarged spleen that was twisted on its long axis but not on its suspensory ligaments. The spleen was excised, and the dog made an uneventful recovery. To the best of our knowledge, this is the first report of a so‐called wandering spleen in a dog, a condition that has been described in humans, albeit rarely. This also is the first report of a twisted spleen in a dog. Veterinary practitioners should include these two possibilities (wandering spleen and twisted spleen) in their list of differential diagnoses when presented with a dog experiencing abdominal discomfort or with an abdominal mass.
Tandem spawning and development in the African freshwater pufferfish Tetraodon schoutedeni
Authors: Momota Kazuyuki , Doi Hiroyuki , Obata Hiroshi , Sakai Harumi 
Published: January 2023

AbstractTo advance breeding techniques for the African freshwater pufferfish Tetraodon schoutedeni and observe tandem spawning closely, we monitored the reproduction of captive individuals. Eight spawning sessions (stable water temperature 24−25°C; daily light period 07:00−19:00) occurred between May 2016 and November 2017. After 65−150 min of tandem swimming (the male biting and clinging to the female's abdomen), 3−50 spherical, weakly adhesive eggs were spawned, being scattered onto the sandy substrate or water plants. The removal of cohabitants (potentially eating spawned eggs) and provision of small initial food items, such as small‐type Brachionus spp., for larval fish were essential for successful breeding.
The influence of a large build area on the microstructure and mechanical properties of PBF-LB Ti-6Al-4 V alloy
Authors: Bagasol Axieh Joy I. , Kaschel Frederico R. , Ramachandran Saranarayanan , Mirihanage Wajira , Browne David J. , Dowling Denis P. 
Published: January 2023

Abstract

This study investigated the print homogeneity of Ti-6Al-4 V alloy parts, when printed over a large build area of 250 $$\times$$
×
250 $$\times$$
×
170 mm3, using a production scale laser powder bed additive manufacturing system. The effect of part location across this large build area was investigated based on printed part porosity, microstructure, hardness, and tensile properties. In addition, a Hot Isostatic Pressing (HIP) treatment was carried out on the as-built parts, to evaluate its impact on the material properties. A small increase in part porosity from 0.01 to 0.09%, was observed with increasing distance from the argon gas flow inlet, which was located on one side of the build plate, during printing. This effect, which was found to be independent of height from the build plate, is likely to be associated with enhanced levels of condensate or spatter residue, being deposited at distances, further from the gas flow. Despite small differences in porosity, no significant differences were obtained for microstructural features such as prior β grain, $$\alpha$$
α
lath thickness, and phase fraction, over the entire build area. Due to this, mechanical performances such as hardness and tensile strengths were also found to be homogenous across the build area. Additionally, it was also observed based on the lattice constants that partial in-situ decomposition of $${\alpha }^{^{\prime}}\to \alpha +\beta$$

α

′

→
α
+
β

phases occurred during printing. Post HIP treatment result showed a decrease of 7 and 6%, in the yield strength (YS) and ultimate tensile strength (UTS), respectively, which was associated with a coarsening of $$\alpha$$
α
lath widths. The potential of the laser powder bed system for large area printing was successfully demonstrated based on the homogenous microstructure and mechanical properties of the Ti-6Al-4 V alloy parts.