bluuebunny/crossref_metadata_2025_split huggingface dataset:
دور الرقابة على دستورية القوانين في إرساء دولة القانون: دراسة مقارنة
Authors: Abdelmounaem BENAHMED 
Published: January 2023

يعتبر الدستور القانون الأساس في الدولة لما يتميز به من سمو شكلي وموضوعي، نظرا لطريقة وضعه من جهة والتي تكون إما بأسلوب الجمعية التأسيسية أو الاستفتاء أو الجمع بينهما، أما من الناحية الموضوعية فإنه يتناول شكل الدولة، نظام الحكم، سلطات الدولة والعلاقة فيما بينها بالإضافة إلى علاقتها بالأفراد الحقوق والحريات...، ونظرا لطبيعة الدستور كأعلى قانون في الدولة لابد أن يكون المرجعية الأولى لمختلف القوانين المتفرعة عنه، ولضمان هذا الارتباط كان لابد من وجود رقابة دستورية تحافظ على احترام الدستور وفي هذا الطرح سنتطرق لمختلف أنواع الرقابة على دستورية القوانين، سواء كانت رقابة امتناع أو إلغاء ونقف على حقيقة فعالية هذه الصور كأدوات رقابية.
Constitution is the basic Law of a state due to its formality and objectivity, and because of the way it is constitutionally codified on one hand and entrenched on the other hand; that which could be achieved through a Constituent Assembly or referendum or the combination of both. On the substantive aspect, constitutional checks and balances deal with the form of the state, system of government, state authorities and the relationship existing between them, as well as its relationship with individual rights and freedoms. Hence, given the nature of the Constitution as the highest law in the state, it must be the first reference to the other branches of laws which emanated from it. In order to guarantee an effective constitutionality of laws through constitutional checks and balances, attempt is made in this paper to address the various types of constitutional checks and balances as well as its role in establishing a state entrenched with the rule of Law, either by means of constitutional censorship or nullification or abrogation. The outcome of this research, therefore, confirms these tools of checks and balances as effective means of entrenching a state of law.
AN ANALYSIS OF INDONESIAN-ENGLISH CODE MIXING USED BY MALE AND FEMALE BROADCASTERS AT SWARAUNIB RADIO STATION
Authors: Ferdiansyah Novri , Arasuli Arasuli , Harahap Alamsyah 
Published: January 2023

The objectives of this research were to find out 1). the most common types of code-mixing used by male and female broadcasters at Swaraunib radio station 2).to find out the reasons for using Indonesian - English code-mixing by male and female broadcasters at Swaraunib Radio station. The subjects of this study were 6 broadcasters at Swaraunib radio station, with 3 male and 3 female broadcasters. The design of this research was descriptive, used quantitative as well as qualitative data. The result showed that there were three types of code-mixing proposed by Hoffman. The results for male broadcasters showed that there were 282 (87%) cases of intra-sentential code mixing, 31 (9,6%) cases of intra-lexical code mixing, and 11 (3,4%) involvement in a change of pronunciation. Meanwhile, the results for female broadcasters showed that there were 357 (89,9%) cases of intra-sentential code mixing, 28 (7,1%) cases of intra-lexical code mixing, and 12 (3%) involvement in a change of pronunciation. While for reasons of using code-mixing, female broadcasters and male broadcasters both used seven reasons from Hoffman's theory. The reasons were talking about particular topic, quoting somebody else, being emphatic about something, interjection, repetition used for clarification, and clarifying the speech content for the interlocutor, and expressing group identity and solidarity In addition, female broadcasters using code-mixing tended to be more conscious and intentional than male broadcasters, and female broadcasters were more expressive than male broadcasters in the use of code-mixing. In conclusion, although the most common types and reasons for using code mixing between male and female broadcasters were similar, there were still differences that were influenced by gender factors. However, code mixing can be used to create a good and interesting communication, especially in broadcasting media.
TRADISI BEJANGO DALAM PERKAWINAN MASYARAKAT SASAK DI DESA SENGKERANG KECAMATAN PRAYA TIMUR KABUPATEN LOMBOK TENGAH
Authors: Mustamiin Muhammad Zainal , Samsul Samsul Hadi 
Published: January 2023

Permasalahan dalam penelitian ini adalah: (1) Bagaimanakah pelaksanaan tradisi Bejango. (2) Nilai-nilai apa saja yang terkandung dalam tradisi Bejango. Tujuan penelitian ini adalah (1) Untuk mengetahui pelaksanaan tradisi Bejango dan (2) Untuk mengetahui nilai-nilai yang terkandung pada tradisi bejango. Jenis penelitian ini adalah jenis penelitian kualitatif dengan metode diskriptif. Informan penelitian ini adalah tokoh agama, tokoh adat, tokoh pemuda dan masyarakat. Responden penelitian ini adalah kepala dusun dan kepala desa. Penentuan jumlah informan dan responden dilakukan dengan teknik purposive. Teknik pengumpulan data yang digunakan dalam penelitian ini adalah wawancara, dan observasi. Data dianalisis dengan menggunakan tehnik analsis kualitatif dengan proses reduksi data, penyajian data, dan menarik kesimpulan. Hasil penelitian ini adalah (1) Tradisi bejango sebagai salah satu rangkaian pernikahan dalam adat sasak sekaligus peningalan leluhur/nenek moyang bangsa sasak dilaksanakan melalui tiga tahap yaitu, tahap persiapan, tahap pelaksanaan dan tahap penutup. Kegiatan pada tahap persiapan antara lain penentuan/menyepkati waktu bejango, mengundang tokoh masyarakat dan keluarga terdekat, musyawarah, menyiapkan perlengkapan dan menyiapkan jaja. Sedangkan kegiatan pada tahap pelaksanaan antara lain kegiatan dirumah pengantin laki-laki, kegiatan dijalan menuju rumah pegantin perempuan dan kegiatan dirumah pengantin perempuan. Sementara kegiatan pada tahap penutup antara lain pembacaan do’a dan salaman. (2) Nilai-nilai yang terkandung pada tradisi bejango adalah nilai sosial budaya yang meliputi nilai kebersamaan, dan nilai silaturrahmi yang ditandai dengan kedatanagan keluarga pengantin laki-laki beserta rombongannya bejango kerumah keluarga pengantin perempuan. Sedangkan nilai budaya yang terkandung dalam tradisi bejango yaitu bagaimana kita diajarkan untuk selalu menjaga dan melestarikan setiap kebudayaan yang menjadi warisan nenek moyang kita, Karena dalam tradisi tersebut mengandung nilai-nilai yang sangat mendalam dan merupakan adat dan tradsisi yang harus tetap diperhankan kuhususunya bagi masyrakat di Desa Sengkerang.Kata Kunci : Nilai, Perkawinan, Bejango, Sosial Budaya
MENINGKATKAN HASILBELAJAR SISWA PADA POKOK BAHASAN PECAHAN DENGAN PERAGA KERTAS LIPAT
Authors: Irfan Ahmad Zainul 
Published: January 2023

Mengingat pentingnya pengembangan kognitif khususnya mengenal pecahan, maka seorang guru harus menggunakan alat peraga dalam setiap menyampaikan pembelajaran agar materi yang disampaikan dapat dipahami siswa. Tujuan penelitian ini adalah untuk meningkatkan Hasil siswa pada pelajaran matematika dalam mengenal pecahan melalui Mandiangin Kecamatan Batukliang Utara, Lombok Tengah. Jenis penelitian ini adalah penelitian tindakan kelas. Penelitian ini dilakukan melalui dua siklus yaitu siklus I dan siklus II yang setiap siklus terdiri dari perencanaan, pelaksanaan, pengamatan dan refleksi. Penelitian minat siswa pada siklus I mencapai peningkatan persentase yang sebelumnya hanya 35% menjadi 63% dan pada siklus II mencapai 78%. Berdasarkan hasil penelitian ini dapat disimpulkan bahwa penggunaan alat peraga dapat meningkatkan hasil belajar siswa pada poko bahasan pecahan dengan peraga kertas lipas pada siswa kelas IV MI NW Tanak Beak, Kab. Lombok TengahKata Kunci : alat peraga kertas lipa, hasil belajar, pecahan
Analisis proses berpikir siswa ditinjau dari wallas dalam menyelesaikan soal matematika pokok bahasan sistem persamaan linier dua variabel di kelas VIII MTs NW Lingsar
Authors: Muzaki Ahmad , Juliangkary Eliska , Stiaman Stiaman 
Published: January 2023

Penelitian ini bertujuan untuk mendeskripsikan proses berpikir siswa ditinjau dari Wallas dalam menyelesaikan soal matematika dengan pokok bahasan Sistem Persamaan Linier Dua Variabel di kelas VIII MTs NW Lingsar Tahaun Pelajaran 2021/2022. Metode yang digunakan dalam penelitian ini adalah deskriptif dengan pendekatan kualitatif. Lokasi penelitian ini adalah di MTs NW Lingsar. Subjek yang digunakan dalam penelitian ini adalah 6 orang siswa yang memiliki kategori tinggi, sedang dan rendah berdasarkan nilai akhir ulangan semester pada matappelajaran matematika.Instrumen yang digunakan dalam penelitian ini sebnayak 3 nomor soal essay pada mataeri Sistem Persamaan Linier Dua Variabel yang berbentuk soal cerita. Teknik pengumpulan data berupa memberikan tes, wawancara serta dokumentasi. Wawancara dilakukan untuk menggali informasi yang lebih mendalam terkait dengan hasil tes tertulis siswa sebelumnya. Adapun teknik analisis data yang digunakan dalam penelitian ini adalah menggunakan 3 tahap yaitu reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian ini menunjukan bahwa dari keseluruhan subjek baik kategori tinggi, sedang dan rendah pada proses persiapan, inkubasi, dan iluminasi siswa mampu memenuhi prose 3 indikator sedangkan di tahap proses verifikasi hanya S1 yang mampu memberikan proses yang benar, sedangkan subjek lain tidak bisa berdasarkan dari teori Wallas
Gender Classification Based on Fingerprint Using Wavelet and Multilayer Perceptron
Authors: Suwarno Sri 
Published: January 2023

Fingerprint-based gender classification is beneficial for speeding up the fingerprint identification of criminals, accident victims, and natural disaster victims that are difficult to be recognized based on their physical characteristics. The biggest obstacle to digitally classifying fingerprints is the image's poor quality. Some methods have been developed to improve image quality through various preprocessing, such as noise removal, background segmentation, thinning, and binarization. However, as these processes increase the classification time, some methods have been developed to classify fingerprints without preprocessing. One of them that has shown excellent success is CNN (Convolutional Neural Network). The method does not require preprocessing, but the computation time is very long and requires large amounts of training data. This study proposed a new method that did not need any preprocessing by using wavelet decomposition combined with the max-pooling process to generate features. Firstly, the fingerprint image was decomposed with a Haar wavelet of 4 levels, and each level was followed by a max-pooling process with a 2´2 filter. After that, the resulting feature was used as training data for the Multilayer Perceptron (MLP) network. In this study, the training data was a dataset from NIST (National Institute of Standart and Technology), with 750 fingerprints consisting of male and female fingerprints, each as many as 375. The method could produce a total accuracy of 80.1%.
Implementation of CV Metha Developing Palembang Goods Ordering System
Authors: Fatmariani Fatmariani , Putri Meidyan Permata , Apriliani Marhama 
Published: January 2023

Abstract
CV Metha Berkembang is one of the companies engaged in the production and sale of aluminum sills. The sales process on CV Metha Berkembang has not been computerized where orders are made with consumers coming directly to the company's location or being able to call the company's phone number. An uncomputerized ordering process is needed in a company, where the ordering system does not require consumers to come to the place. For this reason, an ordering information system is needed that can make it easier for CV Metha Berkembang to carry out ordering activities. The system development method used is the prototype method, while for modeling the system used, namely flowcharts, data flow diagrams and entity relationship diagrams and conducting functional testing with blackbox testing. The result of this final project is in the form of a Website Application that aims to help the ordering process. This application is useful for the admin department to be able to confirm orders and input sold stock data. With this application, it can help consumers, leaders, managers, and admins in processing order data, sales stock, and total stock of goods.
Analysis of Book Distribution Routes Using the Capacity Vehicle Routing Problem (CVRP) Method Using the Sweep Algorithm
Authors: Arifta Ega , Rakhmawati Fibri 
Published: January 2023

Distribution is the process of distributing products from producers to consumers. The ease of consumers in obtaining the desired product is the top priority of every company. In the distribution system, the chosen route is the most important element in determining the distance to be traveled and the costs to be incurred. If the chosen route is optimal, then the distribution system becomes more effective and efficient. Basedon the results of the author's observations, the delivery of goods in the company is still manual and irregular, where the goods are sent from the depot to the consumer and back to the depot so that it takes a lot of time and costs. One solution in solving the distribution problem is the Capacity Vehicle Routing Problem (CVRP). The Sweep algorithm is the simplest clustering method to solve CVRP. In this study, the author used a sweep algorithm because this algorithm is one of the methods that can solve the problem of the distribution route of Quranic books. Based onthe results of the study, researchers compared the distribution route usingthe sweep algorithm and the distributionroute of the previous company, obtained a percentage of total mileage savings of 35.35%, namely from the previous total company mileage of 135.2 Km to 87.4 Km by using the Sweep algorithm. This shows that the CVRP method using the sweep algorithm can provide optimal distance and save company expenses.
A preliminary biomechanical study on trachea reconstruction surgery using the clavicular periosteum
Authors: Zhu Xiaoli , Sun Kangli , Xia Xin , Chen Yu , Sun Anqiang , Chen Xingming 
Published: January 2023

Introduction: The clavicular periosteum is a suitable material for trachea reconstruction. However, because the periosteum is softer and has different mechanical properties than tracheal cartilage, the mechanical loads under physiological conditions after trachea reconstruction may cause collapse or stenosis of the repaired trachea.Methods: In this study, the mechanical properties of the clavicular periosteum were tested, and the 3D trachea geometry was constructed based on CT-scanning images acquired before the surgery. Differing degrees of stenosis (0%, 33%, and 55%) for the repaired trachea sections were predetermined, presenting the different degrees of the tracheal cross-sectional area immediately after clavicular periosteum reconstruction. Then the biomechanical environments of the trachea and the airflow were simulated and analyzed.Results: In the fluid mechanics simulation, the air pressure on the patch area decreased with increasing degrees of stenosis, while the fluid velocity increased as stenosis increased. In solid mechanics simulations, patch area deformation increased as the cross-sectional area of the trachea decreased, and the stress in the patch increased as stenosis increased.Discussion: The solid stress changes may cause tissue remodeling, thickening, and scarring of the patch area. The fluid mechanical changes in the repaired trachea would further aggravate the stenosis. The numerical simulation study would provide references for biomechanical evaluation of trachea reconstruction surgery. The surgical indications may be expanded in the future based on the model prediction results.
Mutational analysis of the spike protein of SARS-COV-2 isolates revealed atomistic features responsible for higher binding and infectivity
Authors: Hanifa Muhammad , Salman Muhammad , Fatima Muqaddas , Mukhtar Naila , Almajhdi Fahad N. , Zaman Nasib , Suleman Muhammad , Ali Syed Shujait , Waheed Yasir , Khan Abbas 
Published: January 2023

Introduction: The perpetual appearance of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2), and its new variants devastated the public health and social fabric around the world. Understanding the genomic patterns and connecting them to phenotypic attributes is of great interest to devise a treatment strategy to control this pandemic.Materials and Methods: In this regard, computational methods to understand the evolution, dynamics and mutational spectrum of SARS-CoV-2 and its new variants are significantly important. Thus, herein, we used computational methods to screen the genomes of SARS-CoV-2 isolated from Pakistan and connect them to the phenotypic attributes of spike protein; we used stability-function correlation methods, protein-protein docking, and molecular dynamics simulation.Results: Using the Global initiative on sharing all influenza data (GISAID) a total of 21 unique mutations were identified, among which five were reported as stabilizing while 16 were destabilizing revealed through mCSM, DynaMut 2.0, and I-Mutant servers. Protein-protein docking with Angiotensin-converting enzyme 2 (ACE2) and monoclonal antibody (4A8) revealed that mutation G446V in the receptor-binding domain; R102S and G181V in the N-terminal domain (NTD) significantly affected the binding and thus increased the infectivity. The interaction pattern also revealed significant variations in the hydrogen bonding, salt bridges and non-bonded contact networks. The structural-dynamic features of these mutations revealed the global dynamic trend and the finding energy calculation further established that the G446V mutation increases the binding affinity towards ACE2 while R102S and G181V help in evading the host immune response. The other mutations reported supplement these processes indirectly. The binding free energy results revealed that wild type-RBD has a TBE of −60.55 kcal/mol while G446V-RBD reported a TBE of −73.49 kcal/mol. On the other hand, wild type-NTD reported −67.77 kcal/mol of TBE, R102S-NTD reported −51.25 kcal/mol of TBE while G181V-NTD reported a TBE of −63.68 kcal/mol.Conclusions: In conclusion, the current findings revealed basis for higher infectivity and immune evasion associated with the aforementioned mutations and structure-based drug discovery against such variants.
Lethal activity of BRD4 PROTAC degrader QCA570 against bladder cancer cells
Authors: Wang Qiang , Li Baohu , Zhang Wenkai , Li Zhuoyue , Jiang Bo , Hou Sichuan , Ma Shumin , Qin Chong 
Published: January 2023

Bladder cancer is the most common malignancy of the urinary system. Efforts to identify innovative and effective therapies for bladder cancer are urgently needed. Recent studies have identified the BRD4 protein as the critical factor in regulation of cell proliferation and apoptosis in bladder cancer, and it shows promising potential for pharmacologic treatment against bladder cancer. In this study, we have evaluated the biological function of QCA570, a novel BET degrader, on multiple bladder cancer cells and explore its underlying mechanisms. QCA570 potently induces degradation of BRD4 protein at nanomolar concentrations, with a DC50 of ∼ 1 nM. It decreases EZH2 and c-MYC levels by transcriptional suppression and protein degradation. Moreover, the degrader significantly induces cell apoptosis and cycle arrest and shows antiproliferation activity against bladder cancer cells. These findings support the potential efficacy of QCA570 on bladder cancer.
Pro-inflammatory role of Wnt/β-catenin signaling in endothelial dysfunction
Authors: Wadey Kerry S. , Somos Alexandros , Leyden Genevieve , Blythe Hazel , Chan Jeremy , Hutchinson Lawrence , Poole Alastair , Frankow Aleksandra , Johnson Jason L. , George Sarah J. 
Published: January 2023

BackgroundEndothelial dysfunction is a critical component of both atherosclerotic plaque formation and saphenous vein graft failure. Crosstalk between the pro-inflammatory TNF-α-NFκB signaling axis and the canonical Wnt/β-catenin signaling pathway potentially plays an important role in regulating endothelial dysfunction, though the exact nature of this is not defined.ResultsIn this study, cultured endothelial cells were challenged with TNF-α and the potential of a Wnt/β-catenin signaling inhibitor, iCRT-14, in reversing the adverse effects of TNF-α on endothelial physiology was evaluated. Treatment with iCRT-14 lowered nuclear and total NFκB protein levels, as well as expression of NFκB target genes, IL-8 and MCP-1. Inhibition of β-catenin activity with iCRT-14 suppressed TNF-α-induced monocyte adhesion and decreased VCAM-1 protein levels. Treatment with iCRT-14 also restored endothelial barrier function and increased levels of ZO-1 and focal adhesion-associated phospho-paxillin (Tyr118). Interestingly, inhibition of β-catenin with iCRT-14 enhanced platelet adhesion in cultured TNF-α-stimulated endothelial cells and in an ex vivo human saphenous vein model, most likely via elevating levels of membrane-tethered vWF. Wound healing was moderately retarded by iCRT-14; hence, inhibition of Wnt/β-catenin signaling may interfere with re-endothelialisation in grafted saphenous vein conduits.ConclusionInhibition of the Wnt/β-catenin signaling pathway with iCRT-14 significantly recovered normal endothelial function by decreasing inflammatory cytokine production, monocyte adhesion and endothelial permeability. However, treatment of cultured endothelial cells with iCRT-14 also exerted a pro-coagulatory and moderate anti-wound healing effect: these factors may affect the suitability of Wnt/β-catenin inhibition as a therapy for atherosclerosis and vein graft failure.
Comprehensive analysis of transcriptomics and metabolomics to understand tail-suspension-induced myocardial injury in rat
Authors: Liu Yu , Guo Liguo , Xu Chong , Liu Junlian , Fan Quanchun , Gai Yuqing , Zhao Shuang , Wu Xiaorui , Mi Tao , Wang Jiaping , Li Yongzhi 
Published: January 2023

Background/AimsThe effect and underlying mechanism of microgravity on myocardium still poorly understood. The present study aims to reveal the effect and underlying mechanism of tail-suspension-induced microgravity on myocardium of rats.MethodsTail-suspension was conducted to simulate microgravity in rats. Echocardiography assay was used to detect cardiac function. The cardiac weight index was measured. Hematoxylin and eosin (HE) staining and transmission electron microscopy assay were conducted to observe the structure of the tissues. RNA sequencing and non-targeted metabolomics was employed to obtain transcriptome and metabolic signatures of heart from tail-suspension-induced microgravity and control rats.ResultsMicrogravity induced myocardial atrophy and decreased cardiac function in rats. Structure and ultrastructure changes were observed in myocardium of rats stimulated with microgravity. RNA sequencing for protein coding genes was performed and identified a total of 605 genes were differentially expressed in myocardium of rats with tail suspension, with 250 upregulated and 355 downregulated (P &lt; 0.05 and | log2fold change| &gt; 1). A total of 55 differentially expressed metabolites were identified between the two groups (VIP &gt; 1 and P &lt; 0.05) by the metabolic profiles of heart tissues from microgravity groups and control. Several major pathways altered aberrantly at both transcriptional and metabolic levels, including FoxO signaling pathway, Amyotrophic lateral sclerosis, Histidine metabolism, Arginine and proline metabolism.ConclusionMicrogravity can induce myocardial atrophy and decreases cardiac function in rats and the molecular alterations at the metabolic and transcriptomic levels was observed, which indicated major altered pathways in rats with tail suspension. The differentially expressed genes and metabolites-involved in the pathways maybe potential biomarkers for microgravity-induced myocardial atrophy.