bluuebunny/crossref_metadata_2025_split huggingface dataset:
Advanced Machine Learning Boosting Strategies for Improved Intrusion Detection Performance
Authors: Pulyala Radhika , Boorgam Shiva Yadav , Kakarla Geeta 
Published: September 2023

Abstract
In the rapidly evolving digital landscape, the increased utilization of networks has given rise to numerous security challenges. With the integration of the digital world into society, the emergence of new threats such as viruses and worms has become prevalent. Malicious actors employ various techniques, including password cracking and detecting unencrypted text, to exploit vulnerabilities within computer systems. Consequently, users must prioritize security measures to safeguard their systems against unauthorized intrusions. One well-established method for protecting private networks from external threats is the firewall technique. Firewalls serve as a protective barrier by filtering incoming Internet traffic. However, certain access methods, such as connecting to the Intranet via a modem within the private network, can evade detection by conventional firewalls. To address this issue, a novel system known as a Network Intrusion Detection System (IDS) has been developed to effectively identify and mitigate network attacks. In this project, an Intrusion Detection System utilizing Machine Learning has been developed to accurately determine the presence of intrusions. Multiple models have been constructed using sklearn and ensemble techniques, resulting in exceptional accuracy. This system serves as a proactive approach to bolster network security and confront the constantly developing spectrum of cyber-attacks.
Assessing Anxiety Disorder among Type 2 Diabatic Patients in Damascus, Syria
Authors: Saba Christian , Dagher Rimon , Hammoud Taghreed 
Published: September 2023

Abstract
Introduction:
The incidence of generalized anxiety disorder among individuals with type 2 diabetes has received significant attention from researchers and clinicians alike. While the exact nature of this relationship is complex and still under study, there is a growing body of evidence suggesting that the burden of managing a chronic physical illness may contribute to the development or worsening of anxiety symptoms. Conversely, the emotional and psychological distress associated with generalized anxiety disorder can influence the management and progression of type 2 diabetes.
Methods:
This cross-sectional study was conducted in April 2023 using a convenient sampling pattern. The population was asked to participate voluntarily, and written informed consent was obtained from all participants. They were informed that all their responses were recorded anonymously, that responding to all questions was not mandatory, and that they were allowed to opt out of the survey at any time. The inclusion criteria included type 2 diabetes patients attending the clinic in Damascus Hospital - Syria. The objectives of the study were explained to the participants in a written form attached to the questionnaire.
Results:
The sample in our study consisted of 120 patients with diabetes. Their average age was 57.58 years, with a standard deviation of 15.75 years. The youngest among them was 20 years old, while the oldest among the sample patients was 86 years old.
Also, the average weight of the sample patients was 77.82 kg, with a standard deviation of 14.83 kg. The least weight of the patients was 45 kg, while the largest weight of them was 108 kg. Also with regard to height, the average length of the sample patients was 175.63 cm, with a standard deviation of 12.43 cm, as it was The height of one of the patients, who was considered the shortest, was 150 cm, while the highest value for this variable was 200 cm.
Conclusion:
The latest recommendations regarding the treatment of patients with diabetes should be followed, and diabetic patients should be directed to specialized doctors to evaluate their psychological condition.
Роль трансплантации аутологичных гемопоэтических стволовых клеток в лечении пациентов с системным AL-амилоидозом
Authors: Пирогова Ольга Владиславовна , Кудяшева О. В. , Смирнова А. Г. , Порунова В. В. , Толстова С. В. , Калимулина К. Р. , Черноус М. В. , Власова Ю. Ю. , Моисеев И. С. , Добронравов В. А. , Кулагин А. Д. 
Published: September 2023

Aim. To assess the outcomes of autologous hematopoietic stem cell transplantation (auto-HSCT) in systemic AL Amyloidosis patients treated at the R.M. Gorbacheva Scientific Research Institute of Pediatric Oncology, Hematology and Transplantation.
Materials & Methods. In the period from 2005 to 2022, auto-HSCT was performed in 33 patients with systemic AL Amyloidosis. In 7 of them, auto-HSCT was not preceded by the induction therapy “upfront”. From 2012 all patients received induction therapy prior to transplantation. The median age of patients was 54 years (range 38–68 years); among them there were 17 women and 16 men.
Results. The 3-year follow-up period showed hematological response rate of 76 % (95% confidence interval [95% CI] 50–90 %), heart response rate of 27 % (95% CI 6–55 %), renal response rate of 76 % (95% CI 41–93 %), and hepatic response rate of 26 % (95% CI 8–50 %). The 5-year overall (OS) and progression-free (PFS) survivals were 71 % (95% CI 49–85 %) and 53 % (95% CI 32–71 %), respectively. The OS parameters in the group with delayed auto-HSCT, i.e., after induction therapy, were better than in the “upfront” group: 82 % (95% CI 60–93 %) vs. 43 % (95% CI 10–73 %) (p = 0.03). The OS parameters were affected by health status (p = 0.03), reduced left ventricular ejection fraction < 60 % (p = 0.006), stage of heart disease (p = 0.016), and stage III kidney disease (p = 0.007). The PFS parameters depended on ECOG performance status (p = 0.004) and stage of heart disease (p = 0.041).
Conclusion. The presented data confirm the results of the studies emphasizing the importance of induction therapy prior to auto-HSCT in the treatment of systemic AL Amyloidosis. More stringent parameters of renal function, left ventricular ejection fraction, and ECOG performance status can be used as criteria for auto-HSCT eligibility. Reduced melphalan doses, as conditioning regimen, can be administered to patients with pronounced comorbidity.
The role of alarmins in the pathogenesis of psoriasis
Authors: Mezentsev A. V. , Denisova E. V. , Sobolev V. V. , Korsunskaya I. M. 
Published: September 2023

Alarmins are a group of immune activating proteins/peptides that initiate an inflammatory process by interacting with immune cells. The alarmins are biosynthesized as a result of cell injury, often due to proteolysis of native proteins. Most often, the alarmins are released into the extracellular matrix as a result of infection, burn or trauma. Several studies have been conducted recently to determine the role of alarmins in the pathogenesis of autoimmune diseases. This work was aimed to assess the clinical potential of alarmins and characterize their role in the pathogenesis of psoriasis. The proposed review analysed 6 groups of alarmins with increased expression in the skin of patients with psoriasis: defensins, CAMP/LL-37, amphoterin/HMGB1, interleukin-1 (IL-1)-like cytokine family members (IL1 and -33) with alarmin properties, heat shock proteins, and proteins of the S100 family. The presented work also discusses the therapeutic potential of alarmins: the possibility to use them as the drug therapy target, as well as to establish diagnosis and monitor the progress of psoriasis. The further experimental studies are supposed to pay considerable attention to alarmin receptors, as well as members involved in the signalling pathways they initiated. These work findings help to obtain biologically active compounds that will be able to specifically and effectively inhibit the physiological effects of alarmins, as well as control the inflammatory process they induced. It seems certain that the use of alarmin antagonists in clinical practice will prove useful in the treatment of both psoriasis and other chronic autoimmune diseases, especially in cases where the most commonly used therapies are not effective enough.
TIME CALCULATION METHODS OF THE BUGIS MAKASSAR TRIBE BASED ON THE KU TIKA BOOK
Authors: Sartika Sartika 
Published: September 2023

The Bugis Makassar Tribe Society is one of the tribes in Indonesia that has historical traces in the calendar system. The method of calculating people's time in ancient times was contained in the Ku Tika manuscript of the Bone Tribe which until now is no longer used and is only used as a historical source. Many of today's generations do not know and are no longer able to be read by various backgrounds in society in general. This is because the language used in the text is not the same as today's language, such as the Lontara Bugis language. Therefore, a study is needed regarding the contents of the manuscript so that it can be known by all audiences. This research is included in library research, namely research by collecting data and information from books, journals, and other document records. Based on the results of the research, it can be seen that the Ku Tika manuscript of the Bone tribe explains the meaning of hours, days and months. The time calculation method used is called Pakkita Esso which means the system of five times in one day.
Effect of Ultrasonic Exposure on the Efficiency of De-Oiling Fluid Lecithins
Authors: Lisovaya Ekaterina , Viktorova Elena , Sverdlichenko Anastasia , Zhane Mariet 
Published: September 2023

De-oiling fluid lecithin is a resource- and energy-intensive process that provides a phospholipid isolate with a high content of phospholipids. Ultrasonic exposure is one of the most effective and easy-to-implement physical methods that intensify this chemical-technological procedure. This article describes the effect of ultrasonic exposure on the efficiency of de-oiling fluid lecithins.
The research featured soy lecithin (fluid, partially de-oiled, phospholipid isolate). The de-oiling process involved acetone as a solvent and included three 10-min stages at a temperature of 40°C. The ratio of lecithin:acetone (by weight) was as follows: stage I – 1:7, stage II – 1:6, stage III – 1:5. The systems of fluid lecithin – acetone and partially de-oiled lecithin – acetone underwent ultrasonic treatment during the de-oiling process at different specific power and exposure time. As a result of filtration, phases separated into an acetone solution of neutral lipids and phospholipids. The phospholipid isolate was dried in a vacuum oven at 5 kPa and 40°C. Each stage ended with the following measurements: the content of phospholipids in partially de-oiled lecithins, the content of phospholipids in the phospholipid isolate, and the extraction degree of neutral lipids after distilling the solvent from the acetone miscella.
The specific power in the lecithin – acetone system was 0.28 W/cm3 at de-oiling stage I and 0.36 W/cm3 at stages II and III. Three minutes of ultrasonic exposure at stages I and II and two minutes at stage III reduced the acetone consumption by 1.2 times. The resulting phospholipid isolate yielded by 3.3% more phospholipids than the control sample, which presupposed no ultrasonic treatment.
Ultrasonic exposure proved to be an effective and solvent-saving three-stage method that intensified the process of de-oiling fluid soy lecithin. The study specified the optimal technological modes for obtaining a phospholipid isolate with a high content of phospholipids (98.6%), which can be recommended as a food additive.
Pempek Fishcake from Channa micropeltes with Pumpkin Puree: Quality Assessment
Authors: Adawyah Rabiatul , Dekayanti Tri , Aslamiah Ainun , Wahyu AS Muhammad , Puspitasari Findya 
Published: September 2023

Pempek is an authentic traditional dish of Indonesian cuisine. As a popular food, it needs to be both tasty and nutritious. Mashed pumpkin can add some health-beneficial properties to the traditional pempek and reduce its carbohydrate content. This research featured pempek made of farmed toman fish (Channa micropeltes), which is an affordable raw material. The research objective was to evaluate the consumer acceptance of the experimental pempek based on its sensory assessment and a folding test. This research also revealed the proximate composition, β-carotene, and amino acids in the pempek samples.
The research procedure included the following stages: making pumpkin puree; making pempek by substituting tapioca flour with pumpkin puree (control: 0%, Formulation 1: 10%, Formulation 2: 20%); sensory assessment and folding test; proximate analysis; β-carotene analysis; and amino acid analysis.
A greater proportion of pumpkin puree improved the appearance, color, aroma, flavor, and texture values of the experimental sample. Based on the folding test, the elasticity of pempek decreased as the pumpkin share increased. Pumpkin puree improved the quality of pempek in terms of its protein, moisture, ash, carbohydrate, β-carotene, and amino acid composition. Formulation 2 with 20% of tapioca flour substituted with pumpkin puree showed the best results for protein (7.91%) and amino acids (10.27%), as well as the lowest carbohydrate content (26.76%).
Mashed pumpkin proved to be an excellent substitute of tapioca flour in the traditional Indonesian pempek fishcake as it improved both its sensory profile and nutritional value.
Sourdoughs of Spontaneous (Natural) Fermentation in Modern Bakery Production
Authors: Zharkova Irina , Roslyakov Yuriy , Ivanchikov Danil 
Published: September 2023

Sourdough bakery products have a wide range of tastes and aromas, an extended shelf-life, and other benefits that are important for food producers and consumers. Recent years have seen a growing research interest in the microbiome of bakery sourdoughs. The research objective was to generalize, systematize, and analyze modern data on spontaneous fermentation starters, their production methods, and their role in the technological process at modern bakeries.
The study featured domestic and foreign monographs, research articles, and patents related to various aspects of the production and commercial use of spontaneously fermented baking starters. The search covered publications indexed in PubMed and eLIBRARY.RU in 2000–2022. The sources were selected based on such indicators as completeness, consistency, reliability, and relevance. The obtained data were analyzed and systematized in line with the method of apperception and holography.
The analysis focused on the factors that affect the microbiome of baking starter cultures, in particular, spontaneous fermentation. Another aspect included the effect of the raw materials used at the stage of breeding spontaneous fermentation starter cultures on their quality indicators. The transformation of bioactive compounds in the process of sourdough fermentation proved to be an increasingly relevant research matter. Food producers are looking for more effective tools to develop bakery products with specific nutritional properties, e.g., lower glycemic index, increased content of bioactive nutrients, reduced acrylamide content, low gliadin allergenicity, etc.
The isolation and profiling of microorganisms included in the microbiome of spontaneous fermentation sourdough cultures is of practical interest because new strains might produce starter cultures intended for various target audiences.
New Technology of Functional Bakery Products
Authors: Ladnova Olga , Koryachkina Svetlana , Koryachkin Vladimir , Bolshakova Larisa 
Published: September 2023

Peas (Pisum sativum L.) are rich in protein, B vitamins, and dietary fiber, represented by hemicellulose and pectins. In terms of amino acids, pea proteins are as close to the reference protein as possible. The limiting amino acids of pea protein are sulfur-containing, i.e., methionine and cysteine. Peas are also rich in lysine, which is the limiting amino acid for wheat flour. Therefore, products of pea processing can expand the range of commercial high-protein foods, including functional bakery products. The research objective was to develop a technology for functional bread from a mix of wholemeal pea flour and wheat gluten.
The study featured baking wheat flour, wheat gluten, wholemeal pea flour of San Cipriano and Vega varieties, dough samples, and ready-made bread. The carbohydrate-amylase complex of flour was studied using an Amilotest AT-97 device. The starch content was determined by the polarimetric method. The spectrophotometric method served to test the flower samples for protein while the Kjeldahl method was applied to the bread samples. The rheological properties of the dough were studied on a Reotest 2 viscometer. The sensory evaluation relied on a panel of experts, and the chemical composition was revealed by calculation and analytically.
The wholemeal pea flour had a lower starch gel viscosity compared to the wheat flour sample. A greater amount of flour added during kneading increased the viscosity of the resulting dough. The acidity was rather high: 7.2 and 9.4 degrees for San Cipriano and Vega samples, respectively, and so was the autolytic activity (≤ 80 s). These useful qualities made it possible to reduce the technological process by 115 and 145 min. The resulting bread demonstrated good physical, chemical, and sensory indicators. The high-protein raw materials increased the protein content in bread by 41.9–46.4%, compared to the control sample, which equaled 33.1–34.2% of the recommended daily intake per 100 g of bread.
The optimal ratio of wholemeal high-protein pea flour and wheat gluten was 20/80 for the San Cipriano samples and 30/70 for the Vega variety.
Seasonal Variations in the Biological Value of Kyrgyz Donkey’s Milk Proteins
Authors: Turganbaeva Nadira , Musulmanova Mukarama , Kydyraliev Nurudin 
Published: September 2023

Due to its protein component, donkey’s milk is a multifunctional product with a wide range of beneficial physiological properties. It is known for its antioxidant, anti-inflammatory, rejuvenating, antimicrobial, and antitumor effects. However, the milk of Kyrgyz donkeys has not received proper scientific attention in this respect. This study analyzed the seasonal amino acid profile and biological value of milk obtained from Kyrgyz donkeys.
The donkeys belonged to the Kyrgyz breed and inhabited the highlands of the Chui Region, Republic of Kyrgyzstan. The sampling took place in April, July, and September. The amino acid composition of milk proteins was determined by capillary electrophoresis. The biological value of proteins was assessed by amino acid score, index of essential amino acids (Auxerre index), utility ratio of essential amino acids, and utility ratio of amino acid composition.
The analysis revealed 18 amino acids, including eight essential ones. The total content of amino acids in the spring samples was 1840.07 mg/100 g. In the summer samples, this value peaked at 2037 mg/100 g; in autumn, it dropped to 1264.35 mg/100 g. The changes could be explained by the seasonal differences in the diet. The ratio of essential to non-essential amino acids approached 1:1. The milk also proved to contain arginine, which is an essential amino acid for a juvenile organism. In the spring samples, its content was 2.5 times as big as in the autumn ones. Leucine and isoleucine were responsible for 1/3 of the essential amino acids (322.60 ± 19.35 mg/100 g). The summer samples demonstrated the maximal content of some other essential amino acids, except for valine and tryptophan, which appeared to be the limiting essential amino acids for donkey’s milk in the autumn period. Total essential amino acids in the spring, summer, and autumn samples amounted to 54.24, 59.26, and 34.77 g/100 g, respectively, which exceeded the value for the reference protein (27.46 g/100 g).
Kyrgyz donkey’s milk proteins were of high biological value, regardless of the season, which means that donkey’s milk can become part of new functional products.
Analyzing Overseas Experience in Conducting Marketing Research in Business: Method of Hierarchy Analysis
Authors: Sharapova N. R. 
Published: September 2023

Continuous upgrading in business activity through the process of marketing research is essential for survival of all companies on highly-competitive markets. Analysis of adequate experience and practice dealing with marketing research in business gives an opportunity to influence different aspects of entrepreneurship, such as innovation, access to markets, delivery of human capital, strategic decision-making and others. There is a number of quality estimation of research experience and practice topicality in business activity. However, business quarters, including academic and industrial business people face a problem whether there is a uniform system of estimating scientific and production practices in marketing research aimed at assessing their quality/topicality by several important business characteristics. In view of this the goal of the research is to study overseas experience in conducting marketing research in business sphere in order to produce academic and industrial outlook based on the method of analytical hierarchy. Important estimation characteristics of marketing research in entrepreneurship were obtained in interviews with concerned people and analysis of academic investigations. On this foundation estimation indices and method of hierarchy analysis were elaborated and reasonable values of estimation criteria were fixed. Analysis results show that this model can assess the quality and topicality of marketing research in business objectively, accurately and rationally.
Painted Pottery Decorative Patterns in the North-Eastern Anatolian Plateau during the Late Iron Age (8th–7th century BC to 330 BC)
Authors: Korbi Anete 
Published: September 2023

The article offers a brief overview of the painted pottery decorative patterns on the north-eastern Anatolian plateau during the Late Iron Age. In this study, the author has examined painted pottery sherds of nine archaeological sites: Boğazköy, Alaca Höyük, Alișar Höyük, Ҫadir Höyük, Kerkenes Dağ, Ușaklı Höyük, Mașat Höyük, Kușaklı-Sarissa, Kaman-Kalehöyük. The total amount of painted pottery sherds examined is 344. Based on the evidence of the decorative painted patterns on the ceramic vessels dated to the Late Iron Age, the author has investigated the frequency and distribution of decorative types among the archaeological sites.
Armed Forces of Georgian Democratic Republic in 1918–1921
Authors: Anchabadze George 
Published: September 2023

The article is dedicated to the armed forces of the Georgian Democratic Republic (1918–1921). It shows the history of their creation and development, the composition and structure of the troops, as well as provides a brief insight into the combat path. It also shows the contradictions that existed between the socialist leadership of the country and a significant part of the officer corps, caused by ideological differences. The result of these contradictions were two forms of the armed organization of Georgia – the regular army and the People’s Guard, which caused discord in the armed forces. This circumstance, among other reasons, contributed to the military defeat of Georgia in the clash with Soviet Russia (1921).
Latvijas kultūras un mākslas sovetizācija pirmajā padomju okupācijas gadā: 1940. gada jūnijs – 1941. gada jūnijs
Authors: Stranga Aivars 
Published: September 2023

Kultūras un mākslas attiecības ar jauno varu – padomju režīmu – ir nopietni pētītas Latvijas vēstures literatūrā. Ilgoņa Bērsona darbi par literatūras likteņiem, Arnolda Klotiņa – par mūziku okupācijā un Ilzes Konstantes pētījumi par tēlotāju mākslu ir ievērojami pēdējo gadu sasniegumi. Šajā esejas formas rakstā, papildinot vienu otru faktisko materiālu, veltīta uzmanība kolaborācijai un pat kolaboracionismam. Bez šo parādību plašas izplatības kultūras un mākslas sovetizācijas procesi nebūtu iespējami.