bluuebunny/crossref_metadata_2025_split huggingface dataset:
End-of-Life Systemic Oncologic Treatment in the Immunotherapy Era: The Role of Race, Insurance, and Practice Setting
Authors: Canavan Maureen , Wang Xiaoliang , Ascha Mustafa , Miksad Rebecca , Showalter Timothy N. , Calip Gregory , Gross Cary P. , Adelson Kerin 
Published: June 2023

PURPOSEReceipt of antineoplastic systemic treatment near end of life (EOL) has been shown to harm patient and caregiver experience, increase hospitalizations, intensive care unit and emergency department use, and drive-up costs; yet, these rates have not declined. To understand factors contributing to use of antineoplastic EOL systemic treatment, we explored its association with practice- and patient-level factors.METHODSWe included patients from a real-world electronic health record–derived deidentified database who received systemic therapy for advanced or metastatic cancer diagnosed starting in 2011 and died within 4 years between 2015 and 2019. We assessed use of EOL systemic treatment at 30 and 14 days before death. We divided treatments into three subcategories: chemotherapy alone, chemotherapy and immunotherapy in combination, and immunotherapy (with/without targeted therapy), and estimated conditional odds ratios (ORs) and 95% CIs for patient and practice factors using multivariable mixed-level logistic regression.RESULTSAmong 57,791 patients from 150 practices, 19,837 received systemic treatment within 30 days of death. We observed 36.6% of White patients, 32.7% of Black patients, 43.3% of commercially insured patients, and 37.0% of Medicaid patients received EOL systemic treatment. White patients and those with commercial insurance were more likely to receive EOL systemic treatment than Black patients or those with Medicaid. Treatment at community practices was associated with higher odds of receiving 30-day systemic EOL treatment than treatment at academic centers (adjusted OR, 1.51). We observed large variations in EOL systemic treatment rates across practices.CONCLUSIONIn a large real-world population, EOL systemic treatment rates were related to patient race, insurance type, and practice setting. Future work should examine factors that contribute to this usage pattern and its impact on downstream care.[Media: see text]
Overview of tax measures for personal income tax of the period 2009-2020
Authors: Koutroubi Efstathia 
Published: June 2023

The key components of fiscal policy for a fair and effective tax framework are the implementation of tax reform through a mixture of immediate measures to increase revenue. The Greek income tax system underwent important structural reforms. There was an urgent need to immediately increase the state budget revenues and in the framework of the rescue program of the Greek economy there was a series of legislative interventions. Measures were taken in 2012 to curb the downward trend in revenues, such as expansion of the tax base, reduction of tax exemptions, reduction of taxable income resulting from the restraint of public expenditure due to the adjustment of special payroll. Low levels of growth tend to be one of the main reasons for preventing the collection of personal income taxes. There is a negative correlation between the percentage of tax revenues from personal income taxes and economic growth.
From 2020 major tax changes have been implemented with relief for employees, retirees, families with children, property owners.
This study indicates that prerequisites for a successful tax reform include a holistic approach to the tax system, the evaluation and measurement of concrete reform proposals, as well as the possibility of achieving the objectives and choosing the appropriate timeframe for the adoption of the tax reform in connection with the economic crisis. Also, it provides the financial impact of measures for the taxation undertaken of personal income from 2009 to 2020.

Keywords: Implementation of tax reform, personal income tax, expansion of the tax base, income redistribution

JEL Classifications: H20, H21, H24, H29
Dollar-Cost Average plan in EMU countries: could it be beneficial? What the data say.
Authors: Vasileiou Evangelos , Apostolidis Dimitrios 
Published: June 2023

This study examines a real case scenario using real data under the assumption of a long-term investment horizon. We examine the Dollar Cost Average, Cost Average Plan (CAP) in our case, and attempt to ascertain whether it could prove beneficial for an investor that does not have a significant amount of money to invest when the plan begins. We compare the outcome of the CAP with the alternative scenario of investing a monthly amount in a deposits account, which is in real terms the most comparable plan to the CAP. Using data from January, 2003 to November, 2021 from a wide range of ten (10) European Monetary Union countries, we compare the empirical evidence of these results and we reach the conclusions that CAP outperforms the seasonal bank deposits plan. Moreover, we compare these strategies with the Buy-and-Hold (BnH) strategy, as most studies do, and we conclude that CAP is more beneficial for highly volatile and less uptrend markets than a BnH strategy.

Jel Classifications: G1; G11; N2
Keywords: Dollar Cost Averaging; Investment Strategies; Investment Decisions; Investment Plans.
Measuring behaviour in hens using an ethogram to assess analgesia during further refinement of a high welfare, on-hen, poultry red mite feeding device
Authors: Nunn F. G. , Ewing D. A. , Bartley K. , Palarea-Albaladejo Javier , Chen W. , Price D. R. G. , Nisbet A. J. 
Published: June 2023

Background: To refine an on-hen mite feeding device, an ethogram was employed to measure the reactions of hens during a routine experimental procedure (feather plucking) and to assess effects of analgesic cream on those reactions. Methods: Three experimental groups were used; one treated with EMLA 5% before plucking (“EMLA group”); one with aqueous cream (“placebo group”) and a “no treatment” group. Behaviours were measured and compared on three days: ‘dummy handling day’ i.e. no plucking; ‘plucking day’, plucking the left thigh; and ‘treatment day’ i.e with right thighs plucked post-treatment. Poultry red mite feeding assays were performed to examine effect of creams on mite feeding rates, mortality and fecundity. All data were analysed using generalised linear (mixed) modelling approaches. Results: Use of the ethogram demonstrated no significant difference in hen behaviours in the EMLA group between dummy handling day and treatment day (p = 0.949) alongside a significant reduction in measured behaviours between plucking day and treatment day in the same group (p = 0.028). There was a statistically significant increase in measured behaviours from the dummy handling day to the plucking day in both placebo (p = 0.011) and no treatment group (p < 0.001). Effect sizes and directions were similar between dummy handling and treatment days in the ‘placebo’ and ‘no treatment’ groups, though not statistically significant (placebo, p = 0.064; no treatment p = 0.069). Mite feeding in the EMLA group was significantly lower than in the no treatment group in feeding assay 1 (p = 0.029) only. Mite mortality and fertility were unaffected. Conclusions: The ethogram successfully measured changes in observed behaviours between the dummy handling session and procedures. No adverse effects of EMLA cream on hens were demonstrated at 3mg/kg in hens. Use of analgesia for this routine procedure improves hens’ experiences during experimental trials.
A feasibility study for a unified, multimodal analysis of online information foraging in health-related topics
Authors: Zörgő Szilvia , Peters Gjalt-Jorn , Jeney Anna , Shaffer David Williamson , Ruis Andrew R. , Crutzen Rik 
Published: June 2023

Background: Digital health literacy (DHL) is the ability to find, understand, and appraise online health-related information, as well as apply it to health behavior. It has become a core competence for navigating online information and health service environments. DHL involves solving ill-structured problems, where the problem and its solution are not clearcut and may have no single answer, such as in the process of sensemaking. We employ and expand on information foraging theory to address how experts and novices in information retrieval perform a search task. Our overarching aim is to pinpoint best practices and pitfalls in understanding and appraising health-related information online to develop a digital intervention to increase DHL and critical thinking. Methods: In this feasibility study, we recruited a total of twenty participants for our expert and novice subsamples. We collected sociodemographic data with a self-developed survey, video data through an observation protocol of a 10-minute search task, as well as audio-video data via a retrospective think-aloud. The three, multimodal data streams were transcribed and aligned. Codes were developed inductively in several iterations, then applied deductively to the entire dataset. Tabularized, coded and segmented qualitative data were used to create various quantitative models, which demonstrate viability for the qualitative and statistical comparison of our two subsamples. Results: Data were visualized with Epistemic Network Analysis to analyze code co-occurrences in the three aligned data streams, and with Qualitative/Unified Exploration of State Transitions to examine the order in which participants in our two subsamples encountered online content. Conclusions: This paper describes our methods and planned analyses elaborated with mock figures. Quantifying qualitative data, aligning data streams, and representing all information in a tabularized dataset allows us to group data according to various participant attributes and employ data visualization techniques to pinpoint patterns therein.
In memoriam Profesor Stanisław Salmonowicz (1931–2022) i jego badania nad historią Torunia
Authors: Dygdała Jerzy 
Published: June 2023

Dnia 24 maja 2022 r. zmarł prof. dr hab. Stanisław Salmonowicz, wybitny historyk prawa i ustroju, badacz europejskiego Oświecenia, historii Polski nowożytnej, a także dziejów Polskiego Państwa Podziemnego lat 1939-1945, specjalizujący się również w historii Pomorza i państwa pruskiego, autor około 1350 prac naukowych, popularnonaukowych i publicystycznych. Wychowanek Uniwersytetu Jagiellońskiego w Krakowie, gdzie zaczynał swoją karierę naukową, od 1966 r. aż do końca życia, związany był z Toruniem i spora część jego dorobku naukowego poświęcona była historii, nauce i kulturze tego miasta. Należałoby tu zaliczyć blisko 190 pozycji, w tym 11 książek, 78 artykułów naukowych, 47 biogramów, 20 drobniejszych artykułów popularnonaukowych w miejscowej prasie, 8 notatek z kroniki naukowej oraz 13 nekrologów i wspomnień o zmarłych toruńskich kolegach i przyjaciołach. Szczególne znaczenie mają jego rozprawy poświęcone toruńskiej oświacie i kulturze XVI-XVIII w., a także roli środowisk intelektualnych Torunia w szerzeniu myśli wczesnooświeceniowej w osiemnastowiecznej Rzeczypospolitej.
Minimization Fractional Prophet Inequalities for Sequential Procurement
Authors: Qin Junjie , Vardi Shai , Wierman Adam 
Published: June 2023

We consider a minimization variant on the classical prophet inequality with monomial cost functions. A firm would like to procure some fixed amount of a divisible commodity from sellers that arrive sequentially. Whenever a seller arrives, the seller’s cost function is revealed, and the firm chooses how much of the commodity to buy. We first show that if one restricts the set of distributions for the coefficients to a family of natural distributions that include, for example, the uniform and truncated normal distributions, then there is a thresholding policy that is asymptotically optimal in the number of sellers. We then compare two scenarios based on whether the firm has in-house production capabilities or not. We precisely compute the optimal algorithm’s competitive ratio when in-house production capabilities exist and for a special case when they do not. We show that the main advantage of the ability to produce the commodity in house is that it shields the firm from price spikes in worst-case scenarios. Funding: This work was supported by NSF Grants [CNS-2146814, CPS-2136197, CNS-2106403, NGSDI-2105648].
Hyperglycaemia-related visual seizure
Authors: Thu Win Myat , Zaw Hein Htet 
Published: June 2023

Introduction: Visual seizure is one of the rare complications of poorly controlled chronic hyperglycaemia. This condition can be debilitating for patients. Early recognition and careful control of hyperglycaemia is vital. Case description: A middle-aged female was found collapsed at her home after missing insulin for several days. She was found to have diabetes ketoacidosis (DKA) and she was started on treatment for DKA. She reported visual hallucinations in the right side of her visual field for a week. Further assessment with EEG and brain MRI suggested an occipital seizure consistent with metabolic disturbances. She was initially started on antiepileptic medication. After strict diabetes control, her symptoms resolved, and she no longer needed antiepileptic treatment. Conclusion: Experiencing diabetes-related seizures can be terrifying both for patients and their family. Early recognition and quick control of hyperglycaemia is important in treating these patients.
Hand Hygiene Compliance and Healthcare Associated Infections Trends in a Tertiary Care Children Hospital, in Years 2016-2022
Authors: Ricotta Lara , D’Amore Carmen , Ravà Lucilla , Raponi Massimiliano , Degli Atti Marta Ciofi 
Published: June 2023

Healthcare workers hands are the most common vehicle for the transmission of healthcare-associated infections. Hand hygiene is considered the most effective measure for preventing microbial pathogen cross-transmission, and reducing healthcare-associated infections; thus, it’s key to maintain high healthcare workers compliance with this practice.
We calculated trends of compliance to hand hygiene and healthcare-associated infections (HAIs) point prevalence in a tertiary care children hospital, in years 2016–2022. We observed a significantly increased hand hygiene compliance from 89.5% (95% CI: 89.1-89.9) in 2016 to 92.1% (95% CI: 91.7-92.4; p<0.001) in 2022. Hand hygiene compliance significantly increased for four out of five moments for hand hygiene, and for most of the professional categories observed. We observed a stable trend of HAIs point prevalence which was 1.8% (95% CI: 0.7-3.6) in 2016, and 2.0% (95% CI:1.0-3.7; p=0.6) in 2022. No significant trends were observed over time stratifying by type of HAIs.
Our results document the increased adherence to hand hygiene in the context of pandemic emergency response, associated to maintenance of low prevalence of HAIs.
Do parents get what they want during bad news delivery in NICU?
Authors: Wege Mirjam , von Blanckenburg Pia , Maier Rolf Felix , Knoeppel Carmen , Grunske Albrecht , Seifart Carola 
Published: June 2023

Abstract

Objectives
Little is known about parents’ preferences in breaking bad news (BBN) in neonatology. The study was aimed at comparing parents’ experiences with their first BBN discussion with a neonatologist/pediatric surgeon to their personal preferences.

Methods
We conducted a quantitative survey amongst 54 parents of hospitalized preterm or term infants with severe diseases in two medium-size and one small German neonatal units. Parents answered self-rated questions on how they perceived BBN during their infant’s hospital stay, asking for procedure and perception of BBN, their preferences and satisfaction with BBN.

Results
Overall satisfaction with BBN was moderate to high (median (min–max): 8 (1–10) on a 1–10-Likert scale). A compassionate way of disclosure correlated highest with overall satisfaction with BBN. Thorough transmission of information in an easy to understand manner emerged as another crucial point and correlated significantly to satisfaction with BBN, too. The study revealed that it was highly important for parents, that physicians had good knowledge of the infant and the course of his/her disease, which was only met in a minority of cases. Moreover, there was a major discrepancy between expected and observed professional competence of the delivering physicians. Additionally, physicians did not set aside sufficient time for BBN and parents reported a lack of transporting assurance and hope.

Conclusions
In BBN physicians should draw greatest attention to ensure understanding in parents, with good knowledge of child and disease and sufficient time in a trustworthy manner. Physicians should focus on transporting competence, trust and gentleness.
The Absence of Redemption: A Twentieth-Century Jewish Political Theology
Authors: Batnitzky Leora 
Published: June 2023

Abstract
This article argues that Leo Strauss gives voice to a twentieth-century Jewish theology of the absence of redemption. Using the term “political theology” to characterize Strauss’s thought is unexpected. But this is only surprising because the reception of Strauss remains ensnared with that of Carl Schmitt. The first and last task of this article is to disentangle Strauss from Schmitt. In between the opening and closing frames of separating Strauss from Schmitt, the article fleshes out three points about the political theology of the absence of redemption, each of which brings Strauss into conversation with one of his German-Jewish contemporaries. These points and Strauss’s conversation partners are: 1. the rejection of Christian triumphalism: Franz Rosenzweig; 2. deferral and the possibility of justice: Gershom Scholem; and 3. martyrdom, morality and the seriousness of life: Fritz Baer. The conclusion considers three ways in which a Jewish political theology of the absence of redemption might begin to dislodge Schmitt’s hold on the category of “political theology.”
Contra Schmitt: Walter Benjamin, Leo Strauss and Carl Schmitt
Authors: Liska Vivian 
Published: June 2023

Abstract
This joint essay puts Leo Strauss and Walter Benjamin into conversation regarding their respective relationship to Carl Schmitt. That such a dialogue between the political philosopher regarded as a precursor of neo-conservativism and the idiosyncratic Marxist who continues to inspire the contemporary left can benefit from a comparison of their respective relationships to Carl Schmitt is far from self-evident. Yet, investigating the purported proximity of both Strauss and Benjamin to certain aspects of Schmitt’s thought harbors the promise of illuminating not only their divergent approach to political theology, but also the current interest in Schmitt’s anti-liberal thought. Saving Benjamin and Strauss from their purported proximity to Schmitt allows us to think of their legacies anew. Most importantly in the context of this essay, disentangling Benjamin and Strauss from Schmitt invites us to question the legitimacy of Schmitt’s towering role in the realm of political theology and to highlight these German-Jewish thinkers’ contribution to a twentieth-century Jewish political theology.
The crystal structure of (E)-4-fluoro-N′-(1-(2-hydroxyphenyl)propylidene)benzohydrazide, C16H15FN2O2
Authors: Li Xiaohua , Zhao Xin , Tang Wenqiang 
Published: June 2023

Abstract
C16H15FN2O2, monoclinic, P21/c (no. 14), a = 14.6825(16) Å, b = 11.7155(11) Å, c = 8.8285(7) Å, β = 102.753(10)°, V = 1481.2(2) Å3, Z = 4, Rgt
(F) = 0.0670 wRref
(F
2) = 0.1669, T = 293 K.
What kind of phonation causes the strongest vocal fold collision? – A hemi-larynx phonation contact pressure study
Authors: Scheible Florian , Lamprecht Raphael , Schaan Casey , Veltrup Reinhard , Semmler Marion , Sutor Alexander 
Published: June 2023

Abstract
This paper presents a measurement setup which is able to measure the distribution of small scale pressure on an area of 15.2 mm × 30.4 mm with a sample rate up to 1.2 kHz. It was used to investigate the contact pressures of vocal folds during phonation. This was performed in ex vivo experiments of 11 porcine larynges. The contact pressure at the medial surface and other phonation parameters, as the glottal resistance and the closing velocity of the vocal fold, were measured at different adduction and elongation levels and air flow rates. A statistical analysis was carried out. It could be shown that the contact pressure rises, when the vocal fold is manipulated or when the flow rate is increased.
CARTOGRAFIA SOCIAL NO ENSINO DE GEOGRAFIA: COM A PALAVRA, OS/AS ALUNOS/AS / CARTOGRAPHY SOCIAL AT THE TEACHING OF GEOGRAPHY: WITH WORD, THE STUDENTS
Authors: De Souza Camila Paula , Dias Liz Cristiane 
Published: June 2023

O presente artigo tem como objetivo evidenciar algumas reflexões sobre o processo de ensino e aprendizagem da Cartografia por meio de uma intervenção pedagógica utilizando a Cartografia Social como ferramenta metodológica com os alunos de uma turma do Ensino Médio da Escola Técnica Estadual Profª. Sylvia Mello, localizada na cidade de Pelotas-RS. Para tanto, os alunos realizaram mapeamentos dentro da escola e a confecção de mapas, considerando algumas particularidades e caracteríticas deste contexto escolar, dentre elas: a divisão dos espaços na escola e suas variadas formas de apropriações pelos alunos. Sendo assim, a prática metodológica é dividida em três etapas de realização, a qual teve como cerne a protagonização dos alunos por meio da construção de mapas. Neste estudo, verificou-se a Cartografia Social como uma ferramenta potencializadora ao articular o contexto vivido dos alunos com o ensino da Cartografia e os conceitos geográficos e, além disso, de sólida contribuição para a superação do distanciamento da Cartografia do restante dos conteúdos da disciplina escolar de Geografia.ABSTRACTThe present article aims to highlight some reflections about the teaching and learning process of Cartography through a pedagogical intervention using Social Cartography as a methodological tool with the students of a high school class of the State Technical School Profª. Sylvia Mello, located in the city of Pelotas-RS. In order to do so, the students carried out mapemetry within the school and the making of maps, considering some peculiarities and characteristics of this school context, among them: the division of spaces in the school and its various forms of appropriations by students. Thus, the methodological practice is divided into three stages of realization, which had as its core the protagonism of the students through the construction of maps. In this study, Social Cartography was verified as a potential tool in articulating the lived context of the students with the teaching of Cartography and the geographic concepts and, in addition, a solid contribution to overcome the Cartography distancing from the rest of the contents of the discipline school of Geography.Keywords: Maps; Geography; School
Discursos do Perfil Docente nas Políticas de Formação de Professores
Authors: Figueiredo Marize Peixoto da Silva 
Published: June 2023

Nesse estudo realizou-se uma análise dos discursos do perfil docente em textos da produção acadêmica, interpretando o contexto de sua produção, tendo por base a teoria do discurso como formulada por Ernesto Laclau e Chantal Mouffe.Defende-se que o protagonismo docente sedimentado nos textos alcança hegemonia, articulando demandas diferenciais na relação com um antagonismo constituído no discurso – o gerencialismo docente. Os significantes que assumem centralidade não representam uma essência de professor preexistente ao discurso, mas se constituem na contingência, em resposta ao que é significado como o que bloqueia tais demandas. Pensar o perfil docente como discurso constituído na contingência problematiza a ideia de uma racionalidade, de um projeto de formação, que antecipe e controle a significação da docência. Os discursos do perfil docente e os projetos curriculares para a sua formação se constituem na decisão razoável, uma possibilidade de resposta à diferença. Ressalta-se a produtividade da diferença, do conflito, do dissenso, para a emergência de alternativas na significação do perfil docente e de sua formação.