bluuebunny/crossref_metadata_2025_split huggingface dataset:
Theoretical and experimental analysis of plasma radius expansion model in EDM: a comprehensive study
Authors: Papazoglou Emmanouil L. , Karmiris-Obratański Panagiotis , Karkalos Nikolaos E. , Thangaraj Muthuramalingam , Markopoulos Angelos P. 
Published: March 2023

AbstractElectrical Discharge Machining (EDM) is an established non-conventional process, which is particularly efficient for the processing of hard-to-cut materials, in order to obtain high dimensional accuracy and surface integrity. However, in order to determine the appropriate parameters for machining novel materials, it is necessary to investigate the EDM process in depth, both by experiments and numerical models, taking into consideration the fundamental physical phenomena occurring during this process and be able to predict the surface morphology and microstructural alterations under various conditions. One of the challenging issues of EDM simulation models that still remain open is the representation of the evolution of plasma channel radius, for which various approaches have been proposed such as a linear, power law, or a more complex piecewise relation, in respect to time. Thus, in this work, the effect of different relations for the plasma channel radius evolution on energy absorption coefficient, plasma flushing efficiency (PFE), and crater morphology is compared under various conditions with a numerical model, which is also compared to experimental data. The results indicate that the energy absorption coefficient is dependent on the plasma column radius function, as slower growth of plasma channel leads to lower absorption coefficient and more efficient material removal, whereas a lower variation and different trends under different conditions were observed regarding PFE values, in respect to the power law exponent. Finally, the crater dimensions were shown to be consistently more narrow and deeper with higher exponents; thus, based on actual observations of indicative craters, it was revealed that the appropriate values for the exponent of the power law plasma radius function are below 0.25.
Classification of Genicular Artery Anatomic Variants Using Intraoperative Cone-Beam Computed Tomography
Authors: Callese Tyler E. , Cusumano Lucas , Redwood Karen D. , Genshaft Scott , Plotnik Adam , Stewart Jessica , Padia Siddharth A. 
Published: March 2023

Abstract
Purpose
Genicular artery embolization (GAE) is a new treatment option for symptomatic knee osteoarthritis. Genicular arterial anatomy is complex with limited published reports. This study describes the genicular artery anatomy utilizing intraprocedural cone-beam computed tomography (CBCT) during GAE.

Materials and Methods
This retrospective single-center study was approved by the institutional review board. All patients who underwent GAE between May 2018 and April 2022 were reviewed. Patients with a technically adequate CBCT were included in the analysis. CBCTs were analyzed to determine the presence, course, and branching patterns of the genicular arteries.

Results
A total of 222 patients underwent GAE and 205 (92%) were included for analysis. The descending genicular artery was present in 197 (96%) CBCTs with two branches in 152 (77%). The superior medial genicular artery (SMGA) was present in 186 (91%), superior lateral genicular artery (SLGA) in 203 (99%), inferior medial genicular artery (IMGA) in 195 (95%), inferior lateral genicular artery (ILGA) in 196 (95%), and median genicular artery (MGA) in 200 (97%). Four unique branching patterns were identified: common origin of SLGA and MGA (115, 56%), unique origins (45, 22%), trifurcation of SLGA, SMGA, and MGA (32, 15.5%), and common origin of SMGA and MGA (12, 6%). The recurrent ascending tibial was identified in 156 (76%) CBCTs and superior patellar artery in 175 (85%) CBCTs.

Conclusion
Genicular artery anatomy is complex with numerous common variants. CBCT is a powerful adjunct in GAE to rapidly identify target vessels for embolization and potentially decrease the risk of nontarget embolization.
Stem cell mobilization in multiple myeloma: challenges, strategies, and current developments
Authors: Wei Xiaolei , Wei Yongqiang 
Published: March 2023

AbstractAmong hematological malignancies, multiple myeloma (MM) represents the leading indication of autologous hematopoietic stem cell transplantation (auto-HCT). Auto-HCT is predominantly performed with peripheral blood stem cells (PBSCs), and the mobilization and collection of PBSCs are essential steps for auto-HCT. Despite the improved success of conventional methods with the incorporation of novel agents for PBSC mobilization in MM, mobilization failure is still a concern. The current review comprehensively summarizes various mobilization strategies for mobilizing PBSCs in MM patients and the evolution of these strategies over time. Moreover, existing evidence substantiates that the mobilization regimen used may be an important determinant of graft content. However, limited data are available on the effects of graft characteristics in patient outcomes other than hematopoietic engraftment. In this review, we discussed the effect of graft characteristics on clinical outcomes, mobilization failure, factors predictive of poor mobilization, and potential mobilization regimens for such patients.
Entrectinib dose confirmation in pediatric oncology patients: pharmacokinetic considerations
Authors: Meneses-Lorente Georgina , Guerini Elena , Mercier Francois , Parrott Neil , Kowalski Karey , Chow-Maneval Edna , Buchheit Vincent , Bergthold Guillaume , Fox Elizabeth , Phipps Alex , Djebli Nassim 
Published: March 2023

Abstract
Purpose
Entrectinib is a central nervous system-active potent inhibitor of tropomyosin receptor kinase (TRK), with anti-tumor activity against neurotrophic NTRK gene fusion-positive tumors. This study investigates the pharmacokinetics of entrectinib and its active metabolite (M5) in pediatric patients and aims to understand whether the pediatric dose of 300 mg/m2 once daily (QD) provides an exposure that is consistent with the approved adult dose (600 mg QD).

Methods
Forty-three patients aged from birth to 22 years were administered entrectinib (250–750 mg/m2 QD) orally with food in 4-week cycles. Entrectinib formulations included capsules without acidulant (F1) and capsules with acidulant (F2B and F06).

Results
Although there was interpatient variability with F1, entrectinib and M5 exposures increased dose dependently. Lower systemic exposures were observed in pediatric patients receiving 400 mg/m2 QD entrectinib (F1) versus adults receiving either the same dose/formulation or the recommended flat dose of 600 mg QD (~ 300 mg/m2 for a 70 kg adult) due to suboptimal F1 performance in the pediatric study. The observed pediatric exposures following 300 mg/m2 QD entrectinib (F06) were comparable to those in adults receiving 600 mg QD.

Conclusions
Overall, the F1 formulation of entrectinib was associated with lower systemic exposure in pediatric patients compared with the commercial acidulant formulation (F06). Systemic exposures achieved in pediatric patients with the F06 recommended dose (300 mg/m2) were within the known efficacious range in adults, confirming the adequacy of the recommended dose regimen with the commercial formulation.
Global mean potassium intake: a systematic review and Bayesian meta-analysis
Authors: Reddin Catriona , Ferguson John , Murphy Robert , Clarke Aoibhin , Judge Conor , Griffith Vincent , Alvarez Alberto , Smyth Andrew , Mente Andrew , Yusuf Salim , O’Donnell Martin J. 
Published: March 2023

Abstract
Purpose
Increasing potassium intake, especially in populations with low potassium intake and high sodium intake, has emerged as an important population-level intervention to reduce cardiovascular events. Current guideline recommendations, such as those made by the World Health Organisation, recommend a potassium intake of > 3.5 g/day. We sought to determine summary estimates for mean potassium intake and sodium/potassium (Na/K) ratio in different regions of the world.

Methods
We performed a systematic review and meta-analysis. We identified 104 studies, that included 98 nationally representative surveys and 6 multi-national studies. To account for missingness and incomparability of data, a Bayesian hierarchical imputation model was applied to estimating summary estimates of mean dietary potassium intake (primary outcome) and sodium/potassium ratio.

Results
Overall, 104 studies from 52 countries were included (n = 1,640,664). Mean global potassium intake was 2.25 g/day (57 mmol/day) (95% credible interval (CI) 2.05–2.44 g/day), with highest intakes in Eastern and Western Europe (mean intake 3.53g/day, 95% CI 3.05–4.01 g/day and 3.29 g/day, 95% CI 3.13–3.47 g/day, respectively) and lowest intakes in East Asia (mean intake 1.89 g/day; 95% CI 1.55–2.25 g/day). Approximately 31% (95% CI, 30–41%) of global population included have an estimated potassium intake > 2.5 g/day, with 14% (95% CI 11–17%) above 3.5 g/day.

Conclusion
Global mean potassium intake (2.25 g/day) falls below current guideline recommended intake level of > 3.5 g/day, with only 14% (95% CI 11–17%) of the global population achieving guideline-target mean intake. There was considerable regional variation, with lowest mean potassium intake reported in Asia, and highest intake in Eastern and Western Europe.
Concurrent visual sequence learning
Authors: Wilts Sarah , Haider Hilde 
Published: March 2023

AbstractMany researchers in the field of implicit statistical learning agree that there does not exist one general implicit learning mechanism, but rather, that implicit learning takes place in highly specialized encapsulated modules. However, the exact representational content of these modules is still under debate. While there is ample evidence for a distinction between modalities (e.g., visual, auditory perception), the representational content of the modules might even be distinguished by features within the same modalities (e.g., location, color, and shape within the visual modality). In implicit sequence learning, there is evidence for the latter hypothesis, as a stimulus-color sequence can be learned concurrently with a stimulus-location sequence. Our aim was to test whether this also holds true for non-spatial features within the visual modality. This has been shown in artificial grammar learning, but not yet in implicit sequence learning. Hence, in Experiment 1, we replicated an artificial grammar learning experiment of Conway and Christiansen (2006) in which participants were supposed to learn color and shape grammars concurrently. In Experiment 2, we investigated concurrent learning of sequences with an implicit sequence learning paradigm: the serial reaction time task. Here, we found evidence for concurrent learning of two sequences, a color and shape sequence. Overall, the findings converge to the assumption that implicit learning might be based on features.
Effects of a dynamically changing response set overlap on n − 2 repetition costs
Authors: Scheil Juliane , Kleinsorge Thomas 
Published: March 2023

AbstractN − 2 repetition costs are a marker for inhibition processes during task switching that are supposed to reduce interference from currently irrelevant information. The present study aimed at elucidating effects of response set overlap on n − 2 repetition costs while keeping stimulus set overlap constant. For this purpose, each task was associated with two different response sets. The relevant response set was visually cued in every trial. N − 2 repetition costs were present when the response set overlapped from trial n − 2 to trial n − 1. In contrast, they were abolished when the response set switched. This result is interpreted in terms of stronger interference for overlapping response sets that need to be inhibited to a high degree, resulting in large n − 2 repetition costs. Furthermore, the present results support the notion that two means for interference reduction, task inhibition and task shielding, are deployed in a flexible way depending on environmental demands.
Imperfect diet choice reduces the performance of a predatory mite
Authors: Lemos Felipe , Bajda Sabina , Duarte Marcus V. A. , Alba Juan M. , Van Leeuwen Thomas , Pallini Angelo , Sabelis Maurice W. , Janssen Arne 
Published: March 2023

AbstractTwo mutually unexclusive hypotheses prevail in the theory of nutritional ecology: the balanced diet hypothesis states that consumers feed on different food items because they have complementary nutrient and energy compositions. The toxin-dilution hypothesis poses that consumers feed on different food items to dilute the toxins present in each. Both predict that consumers should not feed on low-quality food when ample high-quality food forming a complete diet is present. We investigated the diet choice ofPhytoseiulus persimilis, a predatory mite of web-producing spider mites. It can develop and reproduce on single prey species, for example the spider miteTetranychus urticae. A closely related prey,T. evansi, is of notorious bad quality forP. persimilisand other predator species. We show that juvenile predators feeding on this prey have low survival and do not develop into adults. Adults stop reproducing and have increased mortality when feeding on it. Feeding on a mixed diet of the two prey decreases predator performance, but short-term effects of feeding on the low-quality prey can be partially reversed by subsequently feeding on the high-quality prey. Yet, predators consume low-quality prey in the presence of high-quality prey, which is in disagreement with both hypotheses. We suggest that it is perhaps not the instantaneous reproduction on single prey or mixtures of prey that matters for the fitness of predators, but that it is the overall reproduction by a female and her offspring on an ephemeral prey patch, which may be increased by including inferior prey in their diet.
Computational modeling of fiber orientation during 3D-concrete-printing
Authors: Reinold Janis , Gudžulić Vladislav , Meschke Günther 
Published: March 2023

AbstractDuring 3D-printing of fiber-reinforced concrete, fibers tend to align with the printing direction due to strong shearing deformation of the material, allowing for the controlled production of components with desired fiber orientation states. The accurate prediction of the fiber orientation state in printed components poses a major challenge due to the large number of processing and material parameters involved and due to the complex mechanisms of flow and fiber reorientation during printing. This contribution presents a novel incorporation of the Folgar–Tucker fiber orientation model within a fluid dynamics framework based on the Particle Finite Element Method for simulations of the fiber orientation evolution during 3D-concrete-printing. The fiber orientation state is represented using a second-order orientation tensor, which is coupled with a new anisotropic Bingham constitutive model used for the viscous fiber-concrete mixture to account for the effect of fiber orientation on the velocity field. Further, the orientation distribution function is reconstructed from the second-order orientation tensor, following the maximum entropy method for a more convenient interpretation of the results. The model is validated by comparing the simulated orientation numbers of a 3D-printed concrete layer for different extrusion nozzle diameters with experimental values from the literature. Several parametric studies are performed to examine the flow and fiber reorientation mechanisms and the influence of process parameters on the fiber orientation state in printed components. Stronger fiber alignment in the printing direction is obtained for higher printing speeds or smaller extrusion nozzles, associated with higher shear stresses developing in the extrusion nozzle.
RETRACTED ARTICLE: Retrospective study of preservation and transection of the round ligament of uterus during laparoscopic transabdominal preperitoneal inguinal hernia repair in adult women
Authors: Zhou Z. , Tong C. , Tian L. , Zhang X. , Li Y. , Xiao Y. , Yan L. 
Published: March 2023

Abstract
Purpose
The processing of the round ligament of uterus in laparoscopic transabdominal preperitoneal (TAPP) repair of inguinal hernia in women has contended. This study aimed to explore whether there is any difference in the surgical outcome and postoperative complications between the two processing modalities, preservation, and transection of the round ligament of uterus, in adult female inguinal hernia patients undergoing TAPP.

Methods
Retrospective analysis of 84 female patients (117 sides) who underwent TAPP in XXX Hospital from July 2013 to August 2022. Patient characteristics and technical details of the surgical procedure were collected and divided into two groups according to whether the round ligament of uterus was severed intraoperatively or not. There were 52 cases (77 sides) in the group with preservation of the round ligament of uterus and 32 cases (40 sides) in the group with transection of the round ligament of uterus, comparing the general condition, surgical condition, and the occurrence of postoperative related complications between the 2 groups.

Results
The operative time for unilateral primary inguinal hernia was (129.2 ± 35.1) and (89.5 ± 42.6) minutes in the preservation and transection groups, respectively. There were no statistical differences between the two groups in terms of age, length of hospital stay, ASA, BMI, history of lower abdominal surgery, type and side of hernia, intraoperative bleeding, and time to surgery for primary bilateral hernia (P > 0.05). In addition, there was likewise no statistical difference in the occurrence of postoperative Clavien–Dindo classification, VAS, seroma, mesh infection, labia majora edema, chronic pain or abnormal sensation in the inguinal region, and hernia recurrence in the two groups as well (P > 0.05).

Conclusion
There is no evidence that the transection of the round ligament of the uterus during TAPP has an impact on postoperative complications in patients. However, given the important role of the uterine round ligament in the surgical management of patients with uterine prolapse and the high incidence of uterine prolapse in older women, hernia surgeons should also be aware of the need to protect the round ligament of uterus in older women.
Risk of cancer after ST-segment-elevation myocardial infarction
Authors: Leening Maarten J. G. , Bouwer Nathalie I. , Ikram M. Arfan , Kavousi Maryam , Ruiter Rikje , Boersma Eric , van den Bos Ewout-Jan , Weevers Auke P. J. D. , Deckers Jaap W. , Levin Mark-David 
Published: March 2023

AbstractAnalyses from administrative databases have suggested an increased cancer incidence among individuals who experienced a myocardial infarction, especially within the first 6 months. It remains unclear to what extent this represents an underlying biological link, or can be explained by detection of pre-symptomatic cancers and shared risk factors.
Cancer incidence among 1809 consecutive patients surviving hospitalization for thrombotic ST-segment-elevation myocardial infarction (STEMI; mean age 62.6 years; 26% women; 115 incident cancers) was compared to the cancer incidence among 10,052 individuals of the general population (Rotterdam Study; mean age 63.1 years; 57% women; 677 incident cancers). Pathology-confirmed cancer diagnoses were obtained through identical linkage of both cohorts with the Netherlands Cancer Registry. Cox models were used to obtain hazards ratios (HRs) adjusted for factors associated with both atherosclerosis and cancer. Over 5-year follow-up, there was no significant difference in the incidence of cancer between STEMI patients and the general population (HR 0.96, 95% CI 0.78–1.19). In the first 3 months after STEMI, cancer incidence was markedly higher among STEMI patients compared to the general population (HR 2.45, 95% CI 1.13–5.30), which gradually dissolved during follow-up (P-for-trend 0.004). Among STEMI patients, higher C-reactive protein, higher platelet counts, and lower hemoglobin were associated with cancer incidence during the first year after STEMI (HRs 2.93 for C-reactive protein > 10 mg/dL, 2.10 for platelet count > 300*109, and 3.92 for hemoglobin < 7.5 mmol/L). Although rare, thrombotic STEMI might be a paraneoplastic manifestation of yet to be diagnosed cancer, and is hallmarked by a pro-inflammatory status and anemia.Trial registration Registered into the Netherlands National Trial Register and WHO International Clinical Trials Registry Platform under shared catalogue number NTR6831.
Burst error-correcting quantum stabilizer codes designed from idempotents
Authors: Ong Kai Lin 
Published: March 2023

AbstractCertain classical codes can be viewed isomorphically as ideals of group algebras, while studying their algebraic structures help extracting the code properties. Research has shown that this was remarkably efficient in the case when the code generators are idempotents. In quantum error correction, the theory of stabilizer formalism requires classical self-orthogonal additive codes over the finite field GF(4), which, via the lens of group algebras, are essentially $$F_2$$

F
2

-submodules over GF(4). Therefore, this paper provides a classification on idempotents in commutative group algebra GF(4)G, followed by a criterion that allows idempotents to generate stabilizer subgroups. Later, the construction of quantum stabilizer codes is done in the case when G is a cyclic group $$C_n$$

C
n

, for $$n=2^m-1$$

n
=

2
m

-
1

and $$n=2^m+1$$

n
=

2
m

+
1

. Quantum bounds on their burst error minimum distance are subsequently determined.
TDD LoRa and Delta Encoding in Low-Power Networks of Environmental Sensor Arrays for Temperature and Deformation Monitoring
Authors: Wielandt Stijn , Uhlemann Sebastian , Fiolleau Sylvain , Dafflon Baptiste 
Published: March 2023

AbstractDensely distributed sensor networks can revolutionize environmental observations by providing real-time data with an unprecedented spatiotemporal resolution. However, field deployments often pose unique challenges in terms of power provisions and wireless connectivity. We present a framework for wirelessly connected distributed sensor arrays for near-surface temperature and/or deformation monitoring. Our research focuses on a novel time division duplex implementation of the LoRa protocol, enabling battery powered base stations and avoiding collisions within the network. In order to minimize transmissions and improve battery life throughout the network, we propose a dedicated delta encoding algorithm that utilizes the spatial and temporal similarity in the acquired data sets. We implemented the developed technologies in a AA battery powered hardware platform that can be used as a wireless data logger or base station, and we conducted an assessment of the power consumption. Without data compression, the projected battery life for a data logger is 4.74 years, and a wireless base stations can last several weeks or months depending on the amount of network traffic. The delta encoding algorithm can further improve this battery life with a factor of up to 3.50. Our results demonstrate the viability of the proposed methods for low-power environmental wireless sensor networks.