bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between BMI and the success rate of transaxillary venous port implantation: a retrospective cohort study
Authors: Shao Fei , Zhang Chunling , Jin Yang , Cai Hao , Pang Yunfeng , Wen Gehua , Ma Chong , Wang Guodong , Sun Ziqiang , Jin Song 
Published: May 2023

Abstract
Background
Fully implantable infusion ports are widely used for long-term chemotherapy in cancer patients. Previous studies have only focused on the analysis of complications associated with infusion port implantation, ignoring the causes of unsuccessful infusion port implantation. The purpose of this study was to investigate the association between BMI and the success rate of transaxillary intravenous port implantation in breast cancer patients.
Materials and Methods
To review 361 breast cancer patients who underwent intravenous port implantation from January 2021 to September 2021. Baseline data, surgical data, and complications were collected from the patients, and the success rate of puncture of the axillary vein was recorded. The logistic regression analysis and smoothed curve fitting were used to assess the relationship between body mass index (BMI) and the success rate of axillary venipuncture. In addition, subgroup analyses were performed to explore potential interactions.
Results
Under ultrasound guidance, 67.3% of patients (243/361) had an infusion port implanted by axillary vein puncture. There was a roughly linear relationship between BMI and the success rate of axillary venipuncture. In the multiple regression equation, BMI was significantly and negatively associated with the success rate of axillary venipuncture (OR = 0.83; 95%CI = 0.77–0.89; P＜0.001). Stratified analysis showed that the relationship between BMI and the success rate of axillary venipuncture was stable and unaffected by other variables.
Conclusions
The higher the patient's BMI, the higher the chance of difficult axillary venipuncture or failed cannulation.
Luck Clustering in Sports: Applications and Implications for Performance and Strategy
Authors: Farshi Esmaeil 
Published: May 2023

Abstract
The notion of luck clustering has gained traction in recent years due to its potential influence on performance and decision-making across a range of domains. This study concentrates on the application of luck clustering in sports, with an emphasis on its consequences for performance metrics and strategic decision-making. We employ time series analysis to investigate the presence of luck clustering in sports data, such as win-loss records, scoring, and player rankings, while considering the role of the Principle of Luck Conservation in the observed clustering patterns. Our findings provide evidence of luck clustering in sports, implying that periods of high luck tend to be followed by more high luck events, and vice versa for low luck events. These insights carry significant implications for coaches, players, and teams, who can utilize the understanding of luck clustering to develop more effective strategies, manage resources efficiently, and ultimately enhance their performance. By enriching our comprehension of luck's nature and its effects on sports outcomes, this study contributes valuable knowledge for practitioners and researchers in sports analytics and performance management.
A Systems-thinking Approach to Assess the Efficacy of Local Fisheries Management towards Sustainability
Authors: Lukambagire Isaac , Abelson Avigdor , Bhavani Rao R. , N Remya S 
Published: May 2023

Abstract
Unsustainable fishing practices, contribute to a continuous decline in marine fisheries ecosystem resources. However, a lack of understanding on how local systems can be used in fisheries management is evident in literature. This study used a systems-thinking approach to show how local fisheries management practices could be used to promote sustainability in Alappad, Kerala. Systems-thinking entailed understanding of the complex interdependent relationships between the economic, environmental and social factors of a fishery system. The first step involved conducting a systematic literature review and data extraction from peer review journals and official websites. These were analyzed using Excel and R. The second step involved the use of system thinking models comprising causal system dynamics and systems actor mapping to present complex information as interactive relationship maps. Findings highlighted the significance of collaborative decision-making procedures and the necessity of strong governance frameworks for efficient fisheries management. Thus, there’s a need to adopt co-management strategies that take into account practical and proactive knowledge of the fishery operations through effective research methods and local involvement in decision-making processes. This study contributes to the continuing discussion about sustainable fisheries management practices and offers policymakers, managers, and researchers a useful foundation for comprehending the intricate dynamics of the fisheries system in Alappad panchayat and creating effective management measures. These results would contribute to the sustainability of coastal communities and the fisheries on which they depend in Kerala and other regions throughout India and the world.
Hypertension Recommended Self-care Knowledge, Attitude, Practice and Its Predictors among Hypertensive Patients in Ethiopia: A Cross Sectional Study
Authors: Wake Addisu Dabi 
Published: May 2023

Abstract
Introduction:
Globally, hypertension is a significant public health challenge. Elevated BP is responsible for 7.6 million deaths per annum globally, which is greater than any other risk factors. The aim of the study was to assess the hypertension recommended self-care knowledge, attitude, practice and its predictors among hypertensive patients on follow-up clinic.
Methods
A cross-sectional survey was done on 120 hypertensive patients who were on follow-up clinic at Asella Referral and Teaching Hospital. The data were collected from patients from 23/12/2020 to 16/01/2021 by face-to-face interview and medical records review. Data were entered into Epi Data version 4.2.0.0 and exported to SPSS version 23.0 for statistical analysis.
Results
The level of good knowledge, favorable attitude, and good practice towards recommended Self-care was 60.0%, 52.5%, and 50.8%, respectively. The multivariable logistic regression analysis showed that; formal education [AOR = 3.615, 95%CI (1.262, 10.352), p = 0.017], and receiving information about Self-care from healthcare providers during follow-up [AOR = 3.307, 95%CI (1.226, 8.926), p = 0.018] were factors significantly associated with knowledge towards recommended Self-care. Having good knowledge towards Self-care [AOR = 13.449, 95%CI (4.794, 37.728), p = 0.000] was significantly associated with attitude towards recommended Self-care. Receiving information about Self-care from healthcare providers during follow-up was 3.887 times [AOR = 3.887, 95%CI (1.232,12.261), p = 0.021], having good Knowledge towards Self-care [AOR = 3.195, 95%CI (1.161,8.794), p = 0.025], having a favorable attitude towards Self-care [AOR = 3.093, 95%CI (1.198,7.990), p = 0.020] were factors significantly associated with practice towards recommended Self-care.
Conclusion
The level of good knowledge, favorable attitude, and good practice towards recommended Self-care among hypertensive patients on follow-up was unsatisfactory. Health education programs about hypertension self-care are needed to take place to improve their knowledge, attitude, and practice of the patients.
BRCA testing and Japanese original testing criteria for hereditary breast and ovarian cancer covered by public health insurance
Authors: Ohta Kouji , Itoh Tomoko , Katoh Jun 
Published: May 2023

Abstract
In Japan, BRCA1/2 testing has been made available to the public as a companion diagnostic test for olaparib since July 2018. This testing indication has been expanded to diagnosis of hereditary breast and ovarian cancer. The Japanese breast cancer society (JBCS) issued original guidance and criteria to estimate eligibility for BRCA testing among breast cancer patients. This retrospective study aimed to evaluate the current Japanese situation of BRCA testing and the utility of JBCS criteria. We retrospectively reviewed medical records of 1,136 early breast cancer patients. The number of the patients who were eligible for BRCA testing based on JBCS criteria was retrospectively counted. The relationship between the six categories of JBCS and BRCA pathogenicity was evaluated using multivariate analysis. Among the entire cohort, 40.2% met at least one criterion. Being diagnosed with breast cancer at 45 years or younger of age, having two or more primary breast cancers, and being diagnosed with triple negative breast cancer at 60 years or younger significantly increased the likelihood of having BRCA mutation (OR: 8.8, 20.8, 8.6, respectively). In addition, the patients that met two or more testing criteria had higher rates of BRCA mutation than those that met only one criterion. This study suggests that approximately 40% of early breast cancer patients are potential candidates for BRCA testing and/or genetic counseling based on JBSC criteria. Prioritizing the six categories may make the criteria more applicable for use in the current Japanese clinical setting, as genetic practice has limited specialist human resources.
Moxa Cone Moxibustion at Zusanli(ST36) acupoint alleviate myelosuppression mouse induce by CTX and promote hematopoietic cell proliferation via HPA axis
Authors: Tan Li , Li Zhilin , Cao Nan , Li Jing , Ye Zhiyu , Chen Hongda , Wang Ning 
Published: May 2023

Abstract

Objective. Clinical studies have reported that moxibustion alleviates the side effects of chemotherapy, such as myelosuppression; however, its therapeutic mechanisms remain unclear. We investigated whether moxa cone moxibustion (MCM) promotes recovery from chemotherapy-induced myelosuppression via the hypothalamus-pituitary adrenal (HPA) axis.
Methods. A myelosuppression model was established in mice using cyclophosphamide (CTX), and they were grouped into control, model, and moxibustion groups. In the moxibustion group, the mice received MCM at ST36 for 7 days. The peripheral blood cells were detected using an automatic blood cell analyzer; serum levels of corticotropin-releasing hormone (CRH), corticotropin (ACTH), corticosterone (CORT) and glucocorticoid receptor (GRF) a/β were detected using enzyme-linked immunosorbent assay (ELISA); the expression and cell cycle of bone marrow hematopoietic cells were detected using flow cytometry (FC); and BGISEQ Instrument model-DNBseqTM Platform was used for RNA sequencing. The differentially expressed genes (DEGs) were subjected to gene ontology (GO) function enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis.
Results. Compared with the control group, the contents of the peripheral blood and LSK and HSC in the moxibustion group were significantly higher (P<0.05). Following moxibustion therapy, the S and G2 phases of bone marrow hematopoietic stem cells decreased significantly, while the G1 phase increased. The CRH, ACTRH, and CORT levels decreased (P<0.05), while GRF-a and GRFβ levels increased (P<0.05). Additionally, 193 DEGs were down-regulated in the control group and up-regulated in the moxibustion group, while 481 DEGs were up-regulated in the control group and down-regulated in the moxibustion group. GO analysis revealed that cross-DEGs were enriched in cell-cell junction, membrane raft, membrane microdomain, and T-cell receptor complex involved in T-cell activation, T-cell differentiation, and lymphocyte differentiation, which exerted the MF of cytokine binding, receptor activity, and activity. KEGG analysis revealed that hematopoietic cell lineage, primary immunodeficiency, cytokine-cytokine receptor interactions, and other pathways were significantly enriched in the moxibustion group.
Conclusion. MCM could alleviate myelosuppression induced by CTX and promote hematopoietic cell proliferation via the HPA axis and promote the proliferation and differentiation of bone marrow hematopoietic cells by regulating gene expression.
Recent Patents on Rolling Bearing Lubrication Device
Authors: Pan Chengyi , Shao Ruinan , Yan Yubin , Cao Yuanfei 
Published: May 2023

Background:
Rolling bearings are the core components of mechanical equipment. Lubrication plays an important role in the operating performance of rolling bearings. The research on rolling bearing lubrication devices is beneficial to making the bearings obtain the characteristics which is suitable for the working conditions and improving the bearing's service life. Compared with the traditional lubrication devices, the new ones provide assistance to various bearings, solving many problems.

Objective:
To review the latest research on rolling bearing lubrication devices, analyze their solutions to rolling bearing lubrication problems, and discuss their advantages and disadvantages for the reference of scholars and engineers.

Methods:
The representative patents related to rolling bearing lubrication devices are reviewed according to the lubrication method of bearings, including oil lubrication, grease lubrication and solid lubrication. Oil lubrication includes oil mist lubrication, oil-air lubrication, jet lubrication, under ring lubrication and immersion oil lubrication, etc. Grease lubrication includes external and internal lubrication methods. The working principle and characteristics are explained by analyzing the structure of bearing lubrication devices.

Results:
By comparing different types of rolling bearing lubrication devices, the main problems of the current lubrication devices are summarized and analyzed. The future development of rolling bearing lubrication devices are prospected.

Conclusion:
The improvement of rolling bearing lubrication devices is conducive to developing bearing lubrication technology. Advanced mechanical equipments require the rolling bearing lubrication devices to have a simple structure, intelligence, and are easy to be installed.
Evaluation of Activity of Zinc Oxide Nanoparticles on Human Rotavirus
and Multi-Drug Resistant Acinetobacter Baumannii
Authors: Minaeian Sara , Khales Pegah , Hosseini-Hosseinabad Seyed Morteza , Farahmand Mohammad , Poortahmasebi Vahdat , Habib Zahra , Tavakoli Ahmad 
Published: May 2023

Background:
Rotaviruses are the cause of acute gastroenteritis and severe diarrheal diseases
in children worldwide. Children under the age of five are more susceptible to rotavirus infections. Due
to such as the lack of effective drugs and supportive therapy only, the development of new antiviral
agents against rotaviruses is required. Multi-drug-resistant Acinetobacter baumannii is also one of the
most challenging Gram-negative bacteria to control and treat due to its antibiotic resistance, particularly
in intensive care units.

Objective:
This study aimed to investigate the activity of zinc oxide nanoparticles against human rotavirus
and multi-drug resistant Acinetobacter baumannii.

Methods:
The standard 50% tissue culture infectious dose method and the real-time polymerase chain
reaction assay were used to investigate the effects of zinc oxide nanoparticles on rotaviruses. The well
diffusion and the minimum inhibitory concentration method were used to assess the antibacterial activity
of zinc oxide nanoparticles against Acinetobacter baumannii.

Results:
300 μg/ml of zinc oxide nanoparticles demonstrated the highest anti-rotavirus effects, resulting
in a 3.16 logarithmic decrease in virus infectious titer, and a four-unit increase in the cycle threshold
value of the real-time polymerase chain reaction assay compared to the untreated control (P value
<0.001 and P value = 0.005, respectively). The diameter of the inhibition zone of zinc oxide nanoparticles
solution against Acinetobacter baumannii was 17 mm. The minimum inhibitory concentration results
of the zinc oxide nanoparticles solution against Acinetobacter baumannii was 1.56 mg/ml.

Conclusion:
Our findings showed that zinc oxide nanoparticles could be considered a promising antimicrobial
compound.
Standardization of Ready-to-use Therapeutic Food from Locally Available
Food Ingredients in Gujarat, India
Authors: Pramanik Jhilam , Kumar Akash , Phurailatpam Bidyalakshmi 
Published: May 2023

Background:
Malnutrition is associated with high morbidity and death in children under the age of five. A large child population is suffering from severe acute malnutrition (SAM) and it is not possible to admit every child for treatment in hospitals. SAM may be treated simply by providing calorie-dense, protein-rich, vitamin- and mineral-fortified meals at home. In India, there are 132 million children under the age of five, and 8 million of them are affected by malnutrition. As a result, there is a demand for locally made ready-to-use therapeutic food (RUTF) comparable to WHO-recommended RUTF, which should be efficient, safe, and easily accessible.

Objective:
The aim of this study was to develop a RUTF from locally available raw materials, such as barley flour, ghee, peanut, sugar, and flaxseeds.

Methods:
For the development of optimized RUTF, an I-Optimal mixture design with three variable and three non-variable factors was used. Thirty semi-trained panelists participated in sensory analy-sis. The finally optimized RUTF (with high desirability) was further analyzed. The optimized RUTF composition included malted-roasted barley flour (25 gm), roasted peanut (25 gm), powdered sugar (20 gm), desi ghee (20 gm), and roasted flax seeds (10 gm).

Results:
The optimized RUTF (100gm) provided 522.72 ± 0.031 kcal total energy, and the protein-energy, fat–energy, and carbohydrate-energy ratio of RUTF were found to be 11.98 %, 51.66 %, and 37.45 %, respectively.

Conclusion:
The developed RUTF from locally produced is comparable to WHO-approved RUTFs.
Jellyfish Tissue Extract as Inhibition Effect of Jellyfish Olindias sambaquiensis Müller (1861) Sting
Authors: Resgalla Charrid , de Barba Fabiana F. M. , Bazi Carla Camila , Pessatti Marcos Luiz 
Published: May 2023

Background:Olindias sambaquiensis, the most abundant species of jellyfish along the southern coast of Brazil, frequently stings bathers during the summer months, when the occurrence of this species usually reaches a peak.Objective:As jellyfish are rich in protein and carbohydrates, and as these biomolecules could provide a natural defense against stings, this study investigates whether any of the components present in the umbrella of jellyfish species occurring in the south of Brazil can inhibit the nematocyst discharge of the tentacles of 0. sambaquiensis.Methods:Sting tests were conducted in humans, with live tentacles of O. sambaquiensis, to evaluate different lyophilized extracts of different exumbrellar jellyfish tissues obtained at different times of the year to determine their capacity to reduce pain and alter skin color.Results:Of all the species of jellyfish used in this study (O. sambaquiensis, Chiropsalmus quadrumanus and Tamoya haplonema), only the lyophilized extract of the cubozoa C. quadrumanus umbrella showed the capacity to inhibit the pain associated with nematocyst stings.Conclusion:Tests on a lyophilized extract obtained from organisms caught in summer and winter suggested that the biomolecule responsible for the biological activity is carbohydrate since this biomolecule would signal the recognition of the species.
Efeitos da repetição procedimental e da complexidade cognitiva da tarefa no desempenho oral em português língua estrangeira: estudo exploratório
Authors: Santos Sara 
Published: May 2023

Este trabalho apresenta uma análise exploratória relativa aos efeitos da repetição procedimental imediata de tarefas na produção oral de aprendentes de português como língua estrangeira (PLE), quantificada nas dimensões da complexidade linguística, correção e fluência. Partindo dos resultados de um estudo-piloto, foram constituídas três tarefas com um nível de complexidade diferente (simples, complexa ou mais complexa). Cada tarefa foi desempenhada três vezes, sendo cada desempenho baseado numa de três histórias percecionadas com um nível de complexidade semelhante. Participaram neste estudo 21 aprendentes chineses de português como língua estrangeira. Cada participante foi associado a um nível de complexidade e desempenhou três vezes (de cada vez com uma história diferente) a mesma tarefa. Os resultados demonstraram que a repetição da tarefa teve um efeito positivo em dois níveis de complexidade cognitiva: na tarefa simples, ao nível da correção, e na tarefa mais complexa, no que respeita à complexidade sintática (subordinação) e à fluência (velocidade do discurso). O impacto da repetição da tarefa foi mais evidente no segundo desempenho. Considera-se que a repetição procedimental da tarefa poderá ser uma opção metodológica válida no Ensino de Línguas Baseado em Tarefas em PLE. Discutem-se as implicações pedagógicas desta investigação.
UMA NOTA FILOLÓGICA NA DISPERSÃO ARQUIVÍSTICA DA LIMANA, DE LIMA BARRETO
Authors: Souza Arivaldo Sacramento de 
Published: May 2023

Ainda em vida, Lima Barreto enfrentou diversos obstáculos para publicação de obras e, até mesmo, de textos em periódicos mais especializados ou em jornais de ampla circulação. Foi crítico de muitos editores e tipógrafos que o aborreceram muito com erros dos textos por suposta incompreensão de sua letra. Após a sua morte, sua biblioteca foi dispersada e, anos mais tarde, recuperada pelo seu primeiro biógrafo que, juntamente outros intelectuais da palavra, ajudaram a recompor a circulação de Lima Barreto. Neste artigo, discutimos de que maneira a dispersão arquivística de autorias negras tornam as pesquisas de fontes primárias urgentes para construção de argumentos que amplifiquem a fortuna editorial e crítica. Para isso, usamos, como caso paradigmático, os manuscritos preservados na Biblioteca Nacional, seção de Manuscritos, especificamente a Coleção Lima Barreto; a edição do Diário Íntimo do autor; e, por fim, o fac-símile do Inventário também presente na Coleção referida. Com isso, investimos numa leitura filológica que buscou cotejar os manuscritos e o impresso para entender a política editorial definida desde a primeira edição do Diário. Assim, conseguimos compreender que o Diário é uma composição editorial trilhada a partir de índices deixados pelo autor, mas, sobretudo, assumidos pelos editores que investiram na providência de criar uma série textual cronologicamente estabelecida, a fim de dar coerência a papeis que o próprio autor não considerava como dentro de uma cadeia textual.

Palavras-chave: Crítica Filológica; Lima Barreto; Diário Íntimo; Crítica Textual; Manuscritos.
Pendayagunaan Dana Infak dan Sedekah Dalam Program Pilar Ekonomi LAZISNU Kabupaten Tegal
Authors: Hakim Lukmanul , Susanto Dedy , Lestari Widya 
Published: May 2023

Program pilar ekonomi diimplementasikan untuk mengatasi kemiskinan dan pengangguran di Kabupaten Tegal. Studi ini mengevaluasi prosedur yang dilakukan oleh LAZISNU dalam mendistribusikan bantuan kepada para pelaku UMKM dan manfaat yang mereka terima. Metode penelitian yang digunakan adalah deskriptif kualitatif dengan pendekatan studi kasus. Data dikumpulkan melalui wawancara, observasi, dan analisis dokumen. Hasil penelitian menunjukkan bahwa LAZISNU Kabupaten Tegal telah melaksanakan berbagai program pengembangan ekonomi, seperti memberikan modal usaha, pelatihan keterampilan, dan bimbingan usaha, untuk membantu para pelaku UMKM dan masyarakat miskin meningkatkan kesejahteraan dan penghasilan mereka. Program ini membantu mengurangi kesenjangan sosial dan kemiskinan di daerah tersebut. LAZISNU Kabupaten Tegal melibatkan para pelaku UMKM secara langsung dalam menentukan prioritas dan kebutuhan yang tepat.