bluuebunny/crossref_metadata_2025_split huggingface dataset:
Knowledge and Attitudes of Parents, Teachers, and Doctors Regarding Screen Overuse and its Addiction in Children, Adolescents, and Young Adults
Authors: Rao Shirish Ravichandra , Saraf Prashant Harish , Adarkar Shilpa Amit , Inamdar Gayatri Sachin , Mhatre Pauras Pritam , Gupta Vidushi Chandrabhan , Ambike Amey Abhijit , Dedhia Keval Tushar , Raul Shreeya Kuldeepsing 
Published: January 2023

Background:
Media and technology have become an integral part of today's life. Internet addiction, video gaming, binge-watching, social media use, and hence the overall screen time is rising. There are physical, psychological, and social adverse consequences of screen overuse.

Objective:
The objective is to assess the knowledge and attitudes of the study participants and to present solutions for screen addiction.

Subjects and Methods:
A structured questionnaire was developed content validity ratio (CVR >0.65). It was sent via email to more than 500 participants and also on more than 70 WhatsApp groups. It was an online cross-sectional study where 800 participants were recruited using convenience and snowball sampling. Microsoft Excel 2019 and SPSS version 26 were used to obtain and analyze data. P value was determined by using the Chi-square test.

Results:
Knowledge of screen use guidelines and health concerns was highest in doctors followed by teachers and least in parents (P 0.001). 95% of doctors believed any kind of screen overuse should be classified as an addiction. For preventing screen addiction, the role of parents was voted to be most important (49% participants) and for overcoming screen addiction, the role of the person himself was voted to be most important (48% participants).

Conclusion:
The level of knowledge in our study population regarding screen use guidelines was moderate to low. The attitude of parents for tackling their child's screen use was found to be appropriate. The multi-stakeholder approach should be considered for tackling screen addiction.
Z score analysis
Authors: Chauhan Kriti , Bisht Bhumika , Kathuria Komal , Bisht Ritu , Hatwal Varun 
Published: January 2023

Context:
Z score defines the shift of an observed value from the mean.

Aims:
By determining the direction of this shift and its absolute value for mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC), one can quickly screen the hemogram for any spurious results in RBC parameters and also predict the type of anemia. This is because MCH and MCHC are derived parameters (from Hb, RBC, MCV) and thereby reflect the true as well as false changes in an erythrogram.

Materials and Methods:
A total of 975 hemograms were studied retrospectively. Basic statistical formulae using mean and standard deviation were applied to calculate z scores for MCH and MCHC. Results obtained were compared with the standard method and validated by an independent cohort of 100 random samples run on a different machine.

Results and Statistical Analysis:
Z score was found to be statistically significant (p <.001) in diagnosing iron deficiency anemias, megaloblastic anemias, hemolytic anemias, regenerative anemias, anemia of chronic disease and spurious findings. Z score was not significant (p = 0.9) in predicting beta thalassemia trait. The sensitivity was low for the differentials of microcytic hypochromic anemias.

Conclusions:
Despite this, Z score can be of immense help to the clinicians and pathologists in making quick interpretation of the underlying red cell abnormalities. Also, it can be used as a quality assessment tool in hematology laboratories taking pre analytical and analytical factors into account.
Evaluation of tumor budding and its correlation with histomorphological prognostic markers in oral squamous cell carcinoma and its association with the epithelial-mesenchymal transition process
Authors: Yadav Kusum , Singh Tejasvita , Varma Kachnar , Bhargava Mudita , Misra Vatsala 
Published: January 2023

Objective:
To evaluate the association of tumor budding (TB) with prognostic histomorphological parameters in oral squamous cell carcinoma (OSCC) and to investigate the correlation of TB intensity with epithelial to mesenchymal transition (EMT).

Material and Method:
A total of 200 cases diagnosed as OSCC were selected and their TB status was reviewed using Hematoxylin and eosin (H and E) and Immunohistochemistry (IHC). Correlation with histomorphological prognostic parameters was done. Also, IHC for Vimentin and E-cadherin was performed to look for EMT.

Results:
On H and E examination, TB was observed in 154/200 (77%). About 88/154 (57.14%) cases showed a high TB (>5 TB/10 hpf) which increased to 100/154 (64.9%) cases on IHC staining. The intensity of TB was significantly associated with tumor grade and depth of invasion. It was also significantly associated with reduced expression for E-Cadherin and upregulation of Vimentin establishing a pathogenetic correlation between the TB and EMT.

Conclusion:
Therefore, our results suggest that TB is associated with poor prognosis and histologically represents EMT in OSCC which further adds to the aggressiveness of the tumor.
Role of neutrophil-to-lymphocyte, neutrophil-to-eosinophil and platelet-to-lymphocyte ratios in the diagnosis of bullous pemphigoid and Pemphigus disease
Authors: Rai Preethi 
Published: January 2023

Context:
Bullous pemphigoid (BP) and “Pemphigus diseases” (PD) can have overlapping clinical manifestations and accurate distinction is crucial for appropriate management.

Aims:
The study aimed at analyzing the utility of simple hematological markers of systemic inflammation like neutrophil-to-lymphocyte ratio (NLR), neutrophil-to-eosinophil ratio (NER), and platelet-to-lymphocyte ratio (PLR) in clinical decision making in the setting of clinical differentials of BP and PD in a particular case.

Methods:
This single-centre based retrospective observational analytical study included adult subjects newly diagnosed to have BP (n=66) or PD (n=53), confirmed with direct immune-fluorescence testing, over a period of six years. Blood counts performed using Coulter™ hematology analyser, at the time of their initial presentation, were retrieved from the hospital medical records, and the leucocyte ratios were calculated.

Statistical Analysis:
The data were compared between the two groups, using Mann–Whitney U test and chi-square test /Fisher's exact test. ROC curve analysis was performed to estimate cut-off values.

Results:
The BP group had a significantly higher NLR, total leukocyte counts (TLC), absolute eosinophil counts (AEC), and absolute lymphocyte counts (ALC), and lower NER values compared to the PD group (P < 0.05). Areas under ROC for NLR, NER, TLC, AEC, and ALC were between 0.5 and 0.7. NLR ≥ 7, AEC ≥ 2055/cumm, and TLC ≥ 15,000/cumm had a specificity of 90.6, 100, and 100% respectively for identifying BP patients out of the two groups, but with a low sensitivity of 22.7, 21, and 22.7%, respectively.

Conclusions:
NLR can be a valuable diagnostic adjunct in subtyping autoimmune bullous disorders, albeit in a small proportion of cases.
A case of TFE3 translocation renal cell carcinoma with rare morphological features and literature review
Authors: Xia Tian , Long Hanan , Liao Dawei , Wang Wenyuan , Xiao Xiuli 
Published: January 2023

Context:
TFE3 translocation renal cell carcinoma (RCC) is a rare tumor that represents approximately 1% of RCC. It was classifed as a member of MiT family translocation RCCs by the World Health Organization in 2016. It is characterized by Xp11 translocation gene fusions involving TFE3. The diagnosis of TFE3 translocation RCC is based on immunohistochemical analysis and TFE3 break apart probes in FISH analysis, rather than histological characteristics and imaging examination.

Aims:
To determine the clinico-pathological, immuno-phenotypic, and cytogenetic characteristics of TFE3 translocation RCC.

Methods and Materials:
The clinical data of a 52-year-old-female patient with TFE3 translocation RCC exhibiting rare morphological characteristics was analyzed, and the tumor tissues were probed using histopathological staining, immunohistochemistry, and fluorescence in situ hybridization (FISH). In addition, the relevant literature was reviewed.

Results:
This case is a TFE3 translocation RCC with rare morphological features. It composed of two types of tumor cells. TFE3 and pax-8 were diffusely and strongly expressed in both tumor cells, and they were partially positive for CAIX, RCC, CK, EMA, CD10, Vim, Melan-A, and p504s. Only 2% of the cells were positive for the proliferation marker Ki-67, and the tumor was negative for CK7, CD117, Inhibin-α, HBM45, and p53. FISH showed a positive signal for TFE3 translocation.

Conclusions:
This case was a TFE3 translocation RCC with rare morphological features. Through this case report, we emphasize the importance of in situ detection of TFE3 gene translocation and protein in TFE3 translocation RCC.
Kocuria kristinae - An unusual opportunistic pathogen in head and neck malignancy
Authors: Chaubey Priyanka , Mohta Vandana , Mishra Manisha , Wagh Aniruddha , Sapre Satsheel 
Published: January 2023

Introduction:
Kocuria kristinae is a commensal organism, sometimes considered as a lab contaminant, but its repeated isolation from clinical samples in immunocompromised patients should raise red flags.

Materials and Methods:
We confirmed the infection with re-isolation of the organism from the same site before starting treatment. For the identification of Kocuria kristinae we used IDGP cards on VITEK 2 compact system. Antibiotic susceptibility test was done manually following CLSI guidelines 2018 for Coagulase-negative staphylococci.

Results:
A total of 510 major head neck oncosurgeries were performed during the period of two years. Out of which 120 patients had skin and soft tissue infections. Out of these infected patients, 90 were culture positive and of these Kocuria kristinae were isolated in 12 patients. Resistance to penicillin and oxacillin is seen in all isolates.

Conclusion:
Kocuria kristinae should not be ignored as a commensal flora or lab contaminant in immunocompromised hosts. Its Increase in resistance pattern is a matter of concern. It is an ignored opportunistic pathogen whose detailed sensitivity test should be developed to treat patients timely and effectively.
Effect of multimodal sensorimotor training on the stereotypical behavior in children with autism spectrum disorder
Authors: Bhagwasia Himani , Kaur Baljeet 
Published: January 2023

OBJECTIVE:
To analyze the effect of multimodal sensorimotor training on the stereotypical behavior in children with autism spectrum disorder (ASD).

MATERIALS AND METHODS:
A group of 60 children with autism were taken in the study who met the inclusion and exclusion criteria and were grouped into two groups using simple random sampling. Group 1 was the interventional group with 30 participants and Group 2 was control group with 30 participants. A 12-week multi-modal sensorimotor training program was given to Group 1. The control group (Group 2) was also given a 12-week conventional physiotherapy intervention. The outcome measure used was the Indian Scale for Autism Assessment (ISAA). Pretest and posttest findings on ISAA were noted for both groups.

RESULTS:
Multimodal sensorimotor training program has good results compared to the control group in improving the stereotypical behavior in children with ASD. Children who were given conventional physiotherapy programs also showed improvement in their posttest results. On comparing the two groups, multimodal sensorimotor training was found to be more effective in children with ASD.

CONCLUSION:
There is a significant improvement in stereotype behavior, such as head banging, hand flapping, and repetitive behavior. Multimodal sensorimotor training helps to improve the stereotypic behavior in children with ASD. The present study gives a promising intervention program for children with ASD.
Balance training in individuals with Parkinson's disease
Authors: Singh Gurpreet , Jain Tarang Kumar , Colgrove Yvonne M. , Sharma Neena K. , Pahwa Rajesh , Lyons Kelly 
Published: January 2023

OBJECTIVE:
The objective of this study was to evaluate the effect of balance training, using the Biodex Stability System (BSS) or supervised exercises, on balance and gait in individuals with Parkinson's disease (PD).

DESIGN:
This was a prospective, pilot interventional cohort study.

PARTICIPANTS:
Twenty individuals with PD at Hoehn and Yahr stages I–III were included in the study.

INTERVENTIONS:
Ten subjects in the BSS group and 10 subjects in the non-BSS group (supervised balance exercise training without BSS) participated in 55-min exercise sessions 3 times a week for 4 weeks.

OUTCOME MEASUREMENTS:
Postural sway measures-sway area, anterior-posterior (AP) and medial-lateral (ML) center of pressure path length, and root mean square velocity in AP and ML directions were collected at baseline and postintervention. Secondary outcome measures of the Berg Balance Scale (BBS), spatiotemporal gait measures-gait velocity, step length, and stride length, Timed Up and Go, and 6-min walk test data were also collected at baseline and postexercise intervention for both the groups.

RESULTS:
Improvements in postural sway were seen in the BSS group postintervention (sway area mean change = −435.3 mm2; 95% confidence interval = −818.5, −52.2). Postural sway data from the non-BSS group were unavailable, due to a technical failure. All secondary outcome measures improved in both the groups; however, we did not find any significant between-group differences in any of the secondary measures.

CONCLUSIONS:
A 4-week exercise training using BSS improved measures of balance and gait in individuals with PD. However, improvements were also seen after an exercise program that did not use BSS. This suggests that at least for the measures used in this study, there were no differences between BSS training and supervised exercise balance training.
Biomarcadores na cardiomiopatia chagásica como preditores diagnóstico, risco e prognóstico atualizações e associações
Authors: Moreira Pimenta Guilherme , Cerqueira Maia Prates Ludmilla Louise , Soares Lopes Diego Patrick ,  Arango Hector Gustavo , Mota Nobre Sergio Avelino , Chaves Andrade Mariléia 
Published: January 2023

Objetivo: relatar os diversos biomarcadores descritos para a cardiomiopatia chagásica, descrevendo o significado clínico e fisiopatológico em diferentes contextos, isolados ou combinados, diagnóstico, prognóstico, risco e desfecho. Método: Trata-se de uma revisão integrativa da literatura com busca de artigos na base de dados Medical Literature Analysis and Retrieval System Online (MEDLINE), consultada por meio das bases Biblioteca Virtual em Saúde (BVS) e PubMed, utilizando os Descritores em Ciências da Saúde (DeCS) e Medical Subject Headings (MeSH), Chagas cardiomyopathy, Biomarkers, Risk, com recorte temporal de janeiro de 2012 a dezembro de 2021. Foi elaborado um fluxograma com as etapas de identificação, seleção e inclusão dos estudos, e construídos dois quadros para permitir a visualização da estrutura e organização do conteúdo. Resultados: 46 estudos localizados na base MEDLINE, observando-se os critérios do método PRISMA, resultou em 11 artigos incluídos na revisão, em sua maioria estudos de coorte. Considerações finais: Os biomarcadores BNP, NT-proBNP, Troponina, CKMB, com evidências relacionadas à gravidade e risco na cardiomiopatia chagásica, já conhecidos, apresentaram associações consistentes. MMP-2, MMP-9, TIMP-1 e TIMP-2, TNF-α, IL-6, IL-8, IL-10, mostraram associações significativas. Galectina-3, vimentina, 8-OHdG, copeptina, endostatina, hnRNPA1, DHEA-S, cistatina C, igualmente, com associações significativas e com perspectivas para novos estudos.
The Influence of Family Environment, Peer Environment and Social Media on Consumptive Behavior with Religiosity as a Moderating Variable (Study on UIN Salatiga Students Scholarship Recipients)
Authors: Wulan Ndari Ratih , Firmantyas Putri Pertiwi Imanda 
Published: January 2023

Consumptive behavior is the behavior of consuming goods excessively just to meet the demands of lust. This study aims to determine the influence of Family Environment, Peer Environment and Social Media on the Consumptive Behavior of UIN Salatiga scholarship recipients, as well as to find out whether religiosity can moderate the influence of these three variables on consumptive behavior. This research is a quantitative study. The sample involved in this study was 222 UIN Salatiga students who received scholarships. Sample collection using purposive sampling technique. Data collection by spreading questionnaires digitally. The collected data were then analyzed with the Moderated Regression Analisys (MRA) test. From the results of the study, it is known that family environment and social media have no influence on consumptive behavior, while peer environtment has a positive and significant influence on consumptive behavior.
Muslim Consumers Behaviour Through ‘Buy Muslim First (BMF) Vs. ‘Buy Halal First’ (BHF) Campaign in Malaysia
Authors: Mohamad Rasit Rosmawati , Hanin Hamjah Salasiah 
Published: January 2023

The advertisement of products and services whether locally or globally attract consumers and persuade their buying decisions. Muslim consumers in Malaysia make half of the buying power that contributes to the nation’s economy. The buying decision of Muslim consumers shows the highest rating for products that have received halal certification from the Department of Islamic Development Malaysia (JAKIM). In 2018, a ‘Buy Muslim First’ campaign was launched; however, it was misinterpreted as an agenda to boycott the non-Muslim products. The actual purpose of the campaign is to foster the sustainability of entry-level Muslim products in the small-scale industries. Meanwhile the ‘Buy Halal First’ campaign has long been enforced in Malaysia, which allows products manufactured, including by the non-Muslims, to obtain the halal logo. In an Islamic nation such as Malaysia, the halal logo is issued by authoritative institutions that are appointed by the Government such as JAKIM. These authoritative institutions are responsible to ensure that Muslim consumers have options of products which are compliant to the requirements of Islamic rulings even though the products are made by non-Muslim manufacturers. Hence, this article discusses the Muslim consumers’ needs based on the BMF and BHF marketing campaigns.
Kepimpinan Teknologi Guru Besar dan Hubungannya dengan Kompetensi Pengetahuan Teknologi Pedagogi Kandungan Guru SJKC
Authors: Ong Hoay Har , A. Hamid Aida Hanim 
Published: January 2023

Punca guru gagal dalam menguasai kompetensi Pengetahuan Teknologi Pedagogi Kandungan adalah disebabkan guru besar tidak mengamalkan kepimpinan teknologi dengan berkesan. Justeru, tujuan kajian ini adalah untuk menentukan hubungan antara amalan kepimpinan teknologi guru besar dengan kompetensi Pengetahuan Teknologi Pedagogi Kandungan guru SJKC. Sampel kajian ini adalah seramai 178 daripada 206 populasi. Kajian tinjauan ini adalah berdasarkan pendekatan kuantitatif. Instrumen soal selidik diedarkan atas talian secara rawak mudah. Analisis deskriptif dan inferensi adalah melalui perisian SPSS 26.0. Dapatan kajian ini membuktikan bahawa tahap kepimpinan teknologi guru besar secara keseluruhannya berada pada tahap sangat tinggi (min=4.36, SP=0.43) dan tahap kompetensi Pengetahuan Teknologi Pedagogi Kandungan guru juga berada pada tahap sangat tinggi (min=4.28, SP=0.41). Analisis Korelasi Pearson menunjukkan bahawa terhadap hubungan positif yang signifikan dan kuat antara kepimpinan teknologi guru besar dengan kompetensi Pengetahuan Teknologi Pedagogi Kandungan guru (r=0.664; p<0.01). Kesimpulannya, kajian ini membuktikan bahawa kepimpinan teknologi guru besar mampu meningkatkan kompetensi Pengetahuan Teknologi Pedagogi Kandungan guru dengan berkesan sehingga mampu dijadikan sebagai rujukan kepada para penyelidik yang ingin meneroka tajuk kajian ini pada masa depan. Implikasi kajian ini adalah dapat membantu Kementerian Pendidikan Malaysia dalam membina modul tentang amalan kepimpinan teknologi supaya dapat menjayakan Dasar Pendidikan Kebangsaan. Cadangan kajian lanjutan adalah menjalankan kajian dalam bentuk gabungan kualitatif dan kuantitatif agar mampu memberikan impak yang menyeluruh dan positif kepada pihak-pihak berkepentingan dalam bidang pendidikan sehingga pendidikan Malaysia dapat mencapai tahap cemerlang.
DISTRIBUSI UNSUR UTAMA DAN UNSUR TANAH JARANG PADA PELAPUKAN BATUAN GRANITOID DI DAERAH PARMONANGAN, KABUPATEN TAPANULI UTARA
Authors: Nurul Hidayati Ana , Indro Basuki Nurcahyo , Sulaeman  , Sayekti Bayu 
Published: January 2023

Hasil penyelidikan oleh PSDMBP pada tahun 2011 menunjukkan kandungan REE pada pelapukan granitoid di Parmonangan terdapat beberapa unsur dengan anomali yang cukup signifikan seperti Ce (600 s.d. 1400 ppm), La (400 s.d. 1000 ppm), dan Pr (600 s.d. 1400 ppm). Oleh karena itu, penyelidikan lanjutan perlu dilakukan untuk mengetahui persebaran REE ke arah bagian barat dari daerah penyelidikan sebelumnya. Penyelidikan ini bertujuan untuk mengetahui karakteristik granitoid, pola pelapukan, dan profil kandungan REE di daerah penyelidikan.

Pelapukan granitoid di daerah Parmonangan berasal dari granit biotit dan granit biotit hornblende. Karakteristik geokimia hasil pelapukan menunjukkan bahwa Na2O, CaO, K2O, SiO2, P2O5, dan MnO mengalami pelarutan dan bersifat mobile saat berlangsungnya pelapukan sehingga menunjukkan penurunan kadar pada soil dibandingkan batuan dasar. Sedangkan Al2O3, Fe2O3, TiO2, dan LOI menunjukkan kenaikan pada hasil pelapukannya akibat mengalami pengayaan residual.

Kandungan pada pelapukan granitoid daerah Parmonangan menunjukkan pengayaan relatif ΣLREE terhadap ΣHREE. Kandungan ΣLREE dipengaruhi oleh persebaran unsur La dan Ce yang terkandung dalam mineral monasit. Kandungan ΣHREE dikontrol oleh persebaran unsur Y. Berdasarkan korelasi Spearman mineral titanit dan apatit juga berpengaruh pada kelimpahan ΣLREE. Sedangkan mineral pembawa ΣHREE adalah zirkon. Interval sampel berada pada zona pencucian REE sehingga konsentrasi ΣREE yang didapat pada soil lebih rendah dibanding batuan dasar.
The Factors Leading Learners to Fail in End of Year English Test from the Unsuccessful Students Perspective - Erbil Sample
Authors: Dayan Serdar , Yildiz Yunus 
Published: January 2023

Foreign language acquisition is not an easy situation and continues within a certain program and process. Furthermore, no matter what a foreign language it is, the individual who wants to learn the language faces difficulties. These difficulties are sometimes caused by prejudice against speech and the inability to get rid of habits. Since the individuals living in Iraq are a multinational state, the number of people who know at least two languages is quite high. However, while people who acquire languages are good at speaking, their writing skills have not developed well enough. In face-to-face conversations, some prospective students learnt the English language by watching television or playing online games.
This research is a qualitative study. In this study, we evaluated the first-year English language learners' thoughts about their failure at the year-end pass exam through an unstructured face-to-face interview made with 10 students who were subjected to 30 weeks of intensive language education in the 2021-2022 academic year in the language preparatory year of a private university. In the interview, students were asked one open-ended question. Their responses were recorded, not changed and then scripted as they said. As a result, the three most important reasons affecting students' learning of foreign languages were found. These include 1- Internet addiction, 2- Failure to do assigned homework 3- Overconfidence.