bluuebunny/crossref_metadata_2025_split huggingface dataset:
Associations between Socioeconomic Status, Cognition, and Brain Structure: Evaluating Potential Causal Pathways Through Mechanistic Models of Development
Authors: Thomas Michael S. C. , Coecke Selma 
Published: January 2023

AbstractDifferences in socioeconomic status (SES) correlate both with differences in cognitive development and in brain structure. Associations between SES and brain measures such as cortical surface area and cortical thickness mediate differences in cognitive skills such as executive function and language. However, causal accounts that link SES, brain, and behavior are challenging because SES is a multidimensional construct: correlated environmental factors, such as family income and parental education, are only distal markers for proximal causal pathways. Moreover, the causal accounts themselves must span multiple levels of description, employ a developmental perspective, and integrate genetic effects on individual differences. Nevertheless, causal accounts have the potential to inform policy and guide interventions to reduce gaps in developmental outcomes. In this article, we review the range of empirical data to be integrated in causal accounts of developmental effects on the brain and cognition associated with variation in SES. We take the specific example of language development and evaluate the potential of a multiscale computational model of development, based on an artificial neural network, to support the construction of causal accounts. We show how, with bridging assumptions that link properties of network structure to magnetic resonance imaging (MRI) measures of brain structure, different sets of empirical data on SES effects can be connected. We use the model to contrast two possible causal pathways for environmental influences that are associated with SES: differences in prenatal brain development and differences in postnatal cognitive stimulation. We then use the model to explore the implications of each pathway for the potential to intervene to reduce gaps in developmental outcomes. The model points to the cumulative effects of social disadvantage on multiple pathways as the source of the poorest response to interventions. Overall, we highlight the importance of implemented models to test competing accounts of environmental influences on individual differences.
Investigation of the clean patterning possibilities on cotton socks through laser technology
Authors: Atav Rıza , Köksal Daban Sevda , Çetin Erdoğan 
Published: January 2023

AbstractThe aim of this research is to reveal the effect of laser treatment at different resolutions (10, 20 and 30 dpi) and pixel times (80, 100 and 120 μs) on reactive dye uptake of cotton fabrics and the fastness values obtained. Yellowness index, Fourier Transform–infrared analysis, scanning electron microscopy analysis and bursting strength tests were applied to samples. The samples treated with laser were dyed in lighter shades than the untreated ones, with all three of the reactive dyes used in the experiments. In general, colour yield values decreased when the resolution and pixel time increased. However, no significant change was observed in washing, rubbing, light and perspiration fastness values. The possibilities of obtaining various patterns on cotton socks dyed with reactive dyes by laser treatment at different resolutions and pixel times were also investigated. According to the results, it was determined that if laser treatment was not applied to some parts of reactive dyed cotton socks, and 10 dpi 100 μs and 20 dpi 100 μs laser was applied to other parts of those socks, then it was possible to obtain patterns with different shades of the same colour on the socks. On the other hand, laser application after dyeing does not have a negative effect on fastness values. After determining the optimum conditions for the laser process, non‐see‐through tights were produced with cotton yarn on the front and polyester/elastane yarn on the back, and patterns were obtained by applying laser treatment before or after dyeing via sample scale industrial production.
Study of the dyeing properties of saffron and ultrafiltrated saffron powders, as colourants for natural and synthetic fibres
Authors: Naidis Panagiotis , Lykidou Smaro , Mischopoulou Magdalini , Vouvoudi Evangelia , Nikolaidis Nikolaos F. 
Published: January 2023

AbstractThere is a noticeable growing interest in the use of natural dyes in contemporary textile dyeing, motivated by the requirements imposed, in favour of environmental prosperity. The use of natural dyes reduces significantly both the energy requirements and the environmental impact of the process. In the present work natural and synthetic fibres were dyed with the dyestuff isolated from Crocus sativus L., after aqueous extraction of the dried stigmas of the plant. Additionally, part of the powder was purified by using ultrafiltration technology. The saffron extract and the ultrafiltrated saffron retentate were used to dye cotton, wool, nylon and polyester, in various depths of shade and temperatures. Both saffron and ultrafiltrated saffron successfully dyed not only the natural substrates, but also the synthetic ones, while higher dyeing temperatures produced level dyeing with all substrates used. Ultrafiltrated saffron powder produced brighter and much stronger dyeing to the original saffron powder, due to the elimination of extraction by‐products. Isothermal adsorptions for both colourants were performed on all substrates in order to investigate their adsorption mechanism. It was found that saffron and ultrafiltrated saffron follow a Freundlich‐type adsorption isotherm on cotton, wool and nylon which is a typical mechanism for a planar‐directed dye of big molecular weight. Nernst‐type adsorption was found to occur on polyester which again is typical for the adsorption of disperse dyes on polyester. Thus, saffron can be claimed as a universal dye, able to successfully dye natural and synthetic substrates.
Noninvasive assessment of carotid plaque with subharmonic aided pressure estimation from a US contrast agent: A preliminary study
Authors: Li Rui , Zhang Yukang , Zheng Shuai , Cheng Linggang , Zhang Yanfen , Chen Zhiguang , He Wen , Zhang Wei 
Published: January 2023

AbstractStroke is closely associated with carotid plaques. The assessment of carotid plaque is still the key issue of stroke prevention in clinical practice. This prospective cross‐sectional study included patients with carotid plaque evaluated by ultrasonography (US). The intima‐media thickness (IMT), lumen stenosis severity, thickness, and length of carotid plaque were measured by the routine US, and the amplitudes of subharmonics in the upstream shoulder, top, and downstream shoulder of all plaques and corresponding lumens were observed by Subharmonic Aided Pressure Estimation (SHAPE) US examination from the US contrast agent perflubutane microbubbles (Sonazoid), which analyzed the clinical parameters of patients, the subharmonic amplitude characteristics of all plaques and lumens, and the parameter differences between the ischemic stroke (IS) group and control group. From May 2021 to February 2022, 46 carotid plaques of 23 patients were included. For plaques, the subharmonic amplitude in the plaque (−60.52 ± 4.46) was lower than that in the opposing level lumen (−56.82 ± 5.68 dB), the subharmonic gradient across the plaque cap was negatively correlated with plaque thickness (r = −0.51, p < 0.001), and with the lumen stenosis severity (r = −0.42, p = 0.003). The median IMT of the IS group was thicker than the control group. The subharmonic gradient of the intraplaque of the IS group was larger than the control group (p = 0.004). In this analysis, we use the receiver operating characteristic (ROC) curve to establish the cutoff value of the difference to predict a new monitoring method for plaque without invasion to predict IS. It still needs a large‐scale study with long‐term follow‐up to validate these findings.
Characteristic tetraspanin expression patterns mark various tissues during early Xenopus development
Authors: Kuriyama Sei , Tanaka Masamitsu 
Published: January 2023

AbstractThe tetraspanins (Tspans) constitute a family of cell surface proteins with four transmembrane domains. Tspans have been found on the plasma membrane and on exosomes of various organelles. Reports on the function of Tspans during the early development of Xenopus have mainly focused on the expression of uroplakins in gametes. Although the roles of extracellular vesicles (EVs) including exosomes have been actively analyzed in cancer research, the contribution of EVs to early development is not well understood. This is because the diffusivity of EVs is not compatible with a very strict developmental process. In this study, we analyzed members of the Tspan family in early development of Xenopus. Expression was prominent in specific organs such as the notochord, eye, cranial neural crest cells (CNCs), trunk neural crest cells, placodes, and somites. We overexpressed several combinations of Tspans in CNCs in vitro and in vivo. Changing the partner changed the distribution of fluorescent‐labeled Tspans. Therefore, it is suggested that expression of multiple Tspans in a particular tissue might produce heterogeneity of intercellular communication, which has not yet been recognized.
Evaluation of the effect of fiber bridging on mode I quasi‐static testing
Authors: Ben Gur Hila , Banks‐Sills Leslie 
Published: January 2023

AbstractThe purpose of this investigation is to evaluate the contribution of fiber bridging to the energy release rate of a fracture resistance curve. Fiber bridging occurs when testing beam‐type specimens consisting of unidirectional plies in a laminate. Unidirectional double cantilever beam specimens composed of the carbon fiber reinforced polymer prepreg AS4/8552 were tested using standard methods. In addition, a cohesive zone model was developed and used to carry out finite element analyses on the tested specimens. It was employed to calculate the contribution of fiber bridging to the
‐curve which was determined from the tests. Fiber bridging in beam specimens increases the apparent fracture toughness of a composite laminate. A method has been proposed for evaluating its contribution to the energy release rate. In that way, an
‐curve may be determined for which the effect of fiber bridging is eliminated.
Viscoplastic constitutive model considering strain rate sensitivity under multiaxial thermomechanical fatigue loading
Authors: Li Dao‐Hang , Shang De‐Guang , Chen Hong , Cong Ling‐Hua , Wang Jin‐Jie , Mao Zheng‐Yu , Chen Chao‐Lin , Guo Yi‐Er , Yin Xiang 
Published: January 2023

AbstractStrain rate sensitivity will change the cyclic mechanical response of materials under multiaxial thermomechanical fatigue loading; thus, it will lead to errors in fatigue life prediction if strain rate sensitivity is not considered in constitutive simulation. In order to more accurately express the time/rate dependence of viscoplastic behavior, a strain rate sensitivity factor is proposed to modify the viscoplastic function of Chaboche model first. On this basis, a viscoplastic constitutive model considering strain rate sensitivity under multiaxial thermomechanical fatigue loading is proposed, which can describe the varying influence of strain rate sensitivity on cyclic mechanical behavior. Meanwhile, the exponential isotropic hardening rule with the linear term is adopted to characterize the initial rapid softening and subsequent stable softening of the material under fatigue loading at elevated temperature. Moreover, the material‐dependent nonproportional hardening coefficient and the loading path‐dependent rotation factor are used in the kinematic hardening rule to consider the effect of nonproportional additional hardening on the cyclic mechanical behavior of materials. Finally, the proposed method is verified by the stress–strain data of titanium alloy TC4 and Ni‐based superalloy GH4169 under uniaxial and multiaxial thermomechanical fatigue loadings, and a good agreement is obtained.
Crop residue return sustains global soil ecological stoichiometry balance
Authors: Liu Ji , Qiu Tianyi , Peñuelas Josep , Sardans Jordi , Tan Wenfeng , Wei Xiaomeng , Cui Yongxing , Cui Qingliang , Wu Chuanfa , Liu Lanfa , Zhou Baitao , He Haoran , Fang Linchuan 
Published: January 2023

AbstractAlthough soil ecological stoichiometry is constrained in natural ecosystems, its responses to anthropogenic perturbations are largely unknown. Inputs of inorganic fertilizer and crop residue are key cropland anthropogenic managements, with potential to alter their soil ecological stoichiometry. We conducted a global synthesis of 682 data pairs to quantify the responses of soil carbon (C), nitrogen (N), and phosphorus (P) and grain yields to combined inputs of crop residue plus inorganic fertilizer compared with only inorganic fertilizer application. Crop residue inputs enhance soil C (10.5%–12%), N (7.63%–9.2%), and P (2.62%–5.13%) contents, with an increase in C:N (2.51%–3.42%) and C:P (7.27%–8.00%) ratios, and grain yields (6.12%–8.64%), indicating that crop residue alleviated soil C limitation caused by inorganic fertilizer inputs alone and was able to sustain balanced stoichiometry. Moreover, the increase in soil C and C:N(P) ratio reached saturation in ~13–16 years after crop residue return, while grain yield increase trend discontinued. Furthermore, we identified that the increased C, N, and P contents and C:N(P) ratios were regulated by the initial pH and C content, and the increase in grain yield was not only related to soil properties, but also negatively related to the amount of inorganic N fertilizer input to a greater extent. Given that crop residual improvement varies with soil properties and N input levels, we propose a predictive model to preliminary evaluate the potential for crop residual improvement. Particularly, we suggest that part of the global budget should be used to subsidize crop residue input management strategies, achieving to a win‐win situation for agricultural production, ecological protection, and climate change mitigation.
Prenatal weight and regional body composition trajectories and neonatal body composition: The NICHD Foetal Growth Studies
Authors: Widen Elizabeth M. , Burns Natalie , Kahn Linda G. , Grewal Jagteshwar , Backlund Grant , Nichols Amy R. , Rickman Rachel , Foster Saralyn , Nhan‐Chang Chia‐Ling , Zhang Cuilin , Wapner Ronald , Wing Deborah A. , Owen John , Skupski Daniel W. , Ranzini Angela C. , Newman Roger , Grobman William , Daniels Michael J. 
Published: January 2023

SummaryBackgroundGestational weight gain (GWG) and anthropometric trajectories may affect foetal programming and are potentially modifiable.ObjectivesTo assess concomitant patterns of change in weight, circumferences and adiposity across gestation as an integrated prenatal exposure, and determine how they relate to neonatal body composition.MethodsData are from a prospective cohort of singleton pregnancies (n = 2182) enrolled in United States perinatal centres, 2009–2013. Overall and by prepregnancy BMI group (overweight/obesity and healthy weight), joint latent trajectory models were fit with prenatal weight, mid‐upper arm circumference (MUAC), triceps (TSF) and subscapular (SSF) skinfolds. Differences in neonatal body composition by trajectory class were assessed via weighted least squares.ResultsSix trajectory patterns reflecting co‐occurring changes in weight and MUAC, SSF and TSF across pregnancy were identified overall and by body mass index (BMI) group. Among people with a healthy weight BMI, some differences were observed for neonatal subcutaneous adipose tissue, and among individuals with overweight/obesity some differences in neonatal lean mass were found. Neonatal adiposity measures were higher among infants born to individuals with prepregnancy overweight/obesity.ConclusionsSix integrated trajectory patterns of prenatal weight, subcutaneous adipose tissue and circumferences were observed that were minimally associated with neonatal body composition, suggesting a stronger influence of prepregnancy BMI.
Secukinumab demonstrates superiority over narrow‐band ultraviolet B phototherapy in new‐onset moderate to severe plaque psoriasis patients: Week 52 results from the STEPIn study
Authors: Iversen Lars , Conrad Curdin , Eidsmo Liv , Costanzo Antonio , Narbutt Joanna , Pinter Andreas , Kingo Külli , Rivera Diaz Raquel , Kolbinger Frank , Nanna ManikPrabhu , Frueh Jennifer Annika , Jagiello Piotr 
Published: January 2023

AbstractBackgroundBiologic treatments have been studied mainly in patients with a long‐term history of psoriasis and previous treatment failures.ObjectivesThe purpose of this primary analysis of the STEPIn study is to determine whether early intervention with secukinumab in patients with new‐onset moderate to severe plaque psoriasis is superior to standard of care treatment with narrow band ultraviolet B (nb‐UVB) phototherapy.MethodsThe STEPIn study is a randomized, open‐label, multicentre study to investigate early intervention with 52 weeks of secukinumab 300 mg administered subcutaneously versus standard treatment with nb‐UVB phototherapy in patients with new‐onset (≤12 months) moderate to severe plaque psoriasis (NCT03020199). The primary and additional secondary endpoints were ≥90% improvement in Psoriasis Area and Severity Index (PASI 90) at Week 52 and Investigator's Global Assessment (IGA mod 2011) 0/1 response at Week 52, respectively.ResultsIn the secukinumab and nb‐UVB study arms, 77/80 and 76/80 randomized patients received at least one dose of study treatment, respectively. The primary endpoint was achieved: 91.1% (70/77) of patients achieved a PASI 90 response at Week 52 in the secukinumab arm versus 42.3% (32/76) in the nb‐UVB arm (p < 0.0001, odds ratio [OR] estimate [95% confidence intervals, CI] = 16.3 [5.6, 46.9]). The additional secondary endpoint was also achieved: 85.7% of patients achieved an IGA 0/1 response at Week 52 in the secukinumab arm versus 36.8% in the nb‐UVB arm (p < 0.0001). The safety data were consistent with the safety profiles of secukinumab and nb‐UVB with no new or unexpected safety signals.ConclusionsSecukinumab was superior to nb‐UVB in treating patients with new‐onset moderate to severe plaque psoriasis. The high and sustained skin clearance observed indicates that biologic treatment for psoriasis may be more effective if used early in the disease course.
Digital workflow in implant prosthodontics: The critical aspects for reliable accuracy
Authors: Gracis Stefano , Appiani Antonello , Noè Gaetano 
Published: January 2023

AbstractIntroductionThis paper is a comprehensive treaty about the variables that influence the transfer of the position of an implant to the laboratory when using a digital workflow.ObjectiveThe aim is to provide operators and manufacturers with a guide on how to improve certain aspects of the digital workflow specific to the fabrication of implant‐supported restorations.OverviewIt addresses intraoral scanning issues and CAD software issues. In the former, the variables that play a part in the quality of the scan file are investigated: the implant scan body, the IOS and the operator. For the latter, instead, the focus is on those aspects that still today may create inaccuracies in the workflow and in the final product being fabricated: the identification of the specific implant placed in the patient and the generation of a virtual model with the representation of that implant platform correctly positioned in the three dimensions of space. Suggestions and recommendations are given to improve the control on the quality of the digital workflow's output.ConclusionIn a digital workflow for the fabrication of an implant‐supported restoration, the selection and use of the implant scan body, the use of an effective scan strategy and the appropriateness of the best fit function in the CAD software, that is, the procedure of superimposing the library of geometric shapes of the ISB linked to the implant with the shape acquired intraorally, are variables that can influence the positional precision of the FDP.Clinical SignificanceFully understanding the importance of the information enclosed in the ISBs themselves can be crucial in the digital workflow. A proper ISB's selection, a correct scan of the ISB's shape and an accurate CAD superimposition of the ISB's library can lead the clinician to reduce the variables that affect the final result in daily practice.
Effects of temperature on metabolic rate and lower dissolved oxygen tolerance of juvenile speckled peacock bass Cichla temensis
Authors: Coffill‐Rivera Manuel E. , Neal J. Wesley , Allen Peter J. 
Published: January 2023

AbstractThe speckled peacock bass Cichla temensis is a popular sport and food fish that generates substantial angling tourism and utilitarian harvest within its range. Its popularity and value make this species important for management and a potential aquaculture candidate for both fisheries enhancement and food fish production. However, little is known of optimal physiochemical conditions in natural habitats, which also are important for the development of hatchery protocols for handling, spawning and grow‐out. Speckled peacock bass have been documented to have high sensitivity to extreme temperatures, but the metabolic underpinnings have not been evaluated. In this study, the effects of temperature (25, 30 and 35°C) on the standard metabolic rate (SMR) and lower dissolved oxygen tolerance (LDOT) of juvenile speckled peacock bass (mean ± standard error total length 153 ± 2 mm and wet weight 39.09 ± 1.37 g) were evaluated using intermittent respirometers after an acclimation period of 2 weeks. Speckled peacock bass had the highest SMR at 35°C (345.56 ± 19.89 mgO2 kg−1 h−1), followed by 30°C (208.16 ± 12.45 mgO2 kg−1 h−1) and 25°C (144.09 ± 10.43 mgO2 kg−1 h−1). Correspondingly, the Q10, or rate of increase in aerobic metabolic rate (MO2) relative to 10°C, for 30–35°C was also greater (2.76) than from 25 to 30°C (2.08). Similarly, speckled peacock bass were the most sensitive to hypoxia at the warmest temperature, with an LDOT at pO2 of 90 mmHg (4.13 mg l−1) at 35°C compared to pO2 values of 45 mmHg (2.22 mg l−1) and 30 mmHg (1.61 mg l−1) at 30 and 25°C, respectively. These results indicate that speckled peacock bass are sensitive to temperatures near 35°C, therefore we recommend managing and rearing this species at 25–30°C.
An epidemiological analysis of Nocardia seriolae isolated from a wide range of aquatic animals in Taiwan, based on their genotype and enzymatic activity
Authors: Nguyen Phuong , Nazareth Sandra Celenia , Chen Mei‐Yun , Wang Pei‐Chi , Chen Shih‐Chu 
Published: January 2023

AbstractChronic disease following Nocardia seriolae infection in a wide range of aquatic animals has been reported in many Asian countries and recently in America and Mexico. This study aimed to investigate the epidemiological relationship among N. seriolae isolates in Taiwan by investigating their genotype and enzymatic activities. A total of 66 strains isolated from 14 known and four unknown host fish from five sites in Taiwan were characterized using five combined methods. High genotypic diversity was recognized among the isolates with 10 pulsotypes being identified from the pulsed‐field gel electrophoresis method and 21 reptypes from the repetitive extragenic palindromic amplification method; however, no natural plasmids were detected in this bacterial population. Pulsotypes A8 and RI analysed by PFGE and repPCR, respectively, were found to be predominant within five sites in Taiwan over 17 years of isolation. Enzymatically, the majority of isolates displayed high leucine arylamidase, β‐glucosidase and α‐glucosidase activities but were negative for lipase, α‐galactosidase, β‐glucuronidase, N‐acetyl‐glucosaminidase, α‐mannosidase and α‐fucosidase activities. We identified a strong association between genotype and enzymatic activity since the majority of pulsotypes displayed the same type of enzymatic profile. This study provides comprehensive and potential epidemiological data, which will aid the fish farming activities and prevention method development.