bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adverse outcome following selective termination of presenting twin vs non‐presenting twin
Authors: Miremberg H. , Rosen H. , Weisz B. , Tirosh D. , Hershkovitz R. , Stern S. , Porat S. , Beloshevski B. , Melcer Y. , Goldberg Y. , Boms Yonai N. , Awawdeh M. , Leibovitz Z. , Shalev J. , Gindes L. 
Published: February 2023

ABSTRACTObjectiveData are lacking on the impact on pregnancy outcome of the position of the abnormal fetus in a discordant twin pregnancy undergoing selective termination (ST). Tissue maceration post ST of the presenting twin may lead to early rupture of membranes, amnionitis and preterm labor. The aim of this study was to evaluate pregnancy complications and outcome following ST of the presenting vs non‐presenting twin.MethodsThis was a multicenter retrospective cohort study of dichorionic diamniotic twin pregnancies that underwent ST due to a discordant fetal anomaly (structural or genetic) between 2007 and 2021. The study population was divided into two groups according to the position of the reduced twin (presenting or non‐presenting) and outcomes were studied accordingly. The primary outcome was a composite of early complications following ST, including infection, preterm prelabor rupture of membranes and pregnancy loss.ResultsA total of 190 dichorionic twin pregnancies were included, of which 73 underwent ST of the presenting twin and 117 of the non‐presenting twin. The groups did not differ in either baseline demographic characteristics or mean gestational age at the time of the procedure. ST of the presenting twin resulted in a significantly higher rate of early complications compared with the non‐presenting twin (19.2% vs 7.7%; P = 0.018). Moreover, the rates of preterm delivery (75.3% vs 37.6%; P < 0.001) and neonatal intensive care unit admission (45.3% vs 17.1%; P < 0.001) were higher, and birth weight was lower (P < 0.001), in those pregnancies in which the presenting twin was reduced.ConclusionsST of the presenting twin resulted in a higher rate of adverse pregnancy outcome compared with that of the non‐presenting twin. These findings should be acknowledged during patient counseling and, if legislation permits, taken into consideration when planning ST. © 2023 The Authors. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.
Biliary parascarosis in a foal
Authors: Sazmand Alireza , Yavari Morteza , Babaei Mohammad , Nourian Alireza , Otranto Domenico 
Published: February 2023

AbstractMigration of Ascaris lumbricoides through the papilla of Vater in humans, and entry into the biliary tree, is well‐recognised. Ascaris suum and Toxocara vitulorum have been recovered from the liver of swine and buffalo. We necropsied a Persian Kurdish filly at age 6 months, weighing ∼100 kg. Death evidently was caused by oleander (Nerium oleander) intoxication. An 8‐cm adult male Parascaris was found at the lobar‐left hepatic bile duct junction. We suggest that the nematode entered anteriorly into the hepatic tree, via the duodenum, major duodenal papilla, bile duct, left hepatic duct and finally the lobar duct. Considering the brief 4‐h elapsed time between death and necropsy, and the 18‐cm distance from the major duodenal papilla to the location of the parasite, we conclude that entry into the biliary tree likely occurred ante‐mortem. We advise consideration of Parascaris infection in differential diagnosis of equine hepatic and pancreatic dysfunction.
Quantitative analysis of high‐throughput biological data
Authors: Juan Hsueh‐Fen , Huang Hsuan‐Cheng 
Published: February 2023

AbstractThe study of multiple “omes,” such as the genome, transcriptome, proteome, and metabolome has become widespread in biomedical research. High‐throughput techniques enable the rapid generation of high‐dimensional multiomics data. This multiomics approach provides a more complete perspective to study biological systems compared with traditional methods. However, the quantitative analysis and integration of distinct types of high‐dimensional omics data remain a challenge. Here, we provide an up‐to‐date and comprehensive review of the methods used for omics data quantification and integration. We first review the quantitative analysis of not only bulk but also single‐cell transcriptomics data, as well as proteomics data. Current methods for reducing batch effects and integrating heterogeneous high‐dimensional data are then introduced. Network analysis on large‐scale biomedical data can capture the global properties of drugs, targets, and disease relationships, thus enabling a better understanding of biological systems. Current trends in the applications and methods used to extend quantitative omics data analysis to biological networks are also discussed.This article is categorized under:
Data Science > Artificial Intelligence/Machine Learning
Plantation Colonialism in Late Nineteenth-Century Hawai‘i: The Case of Chinese Sugar Planters
Authors: Miller Nicholas B. 
Published: February 2023

AbstractThis chapter defines the force of planter sovereignty in the circa 30-year period in which Hawai‘i witnessed the demographic, topographical, and political ramifications associated with the formation of a migrant labor-based plantation complex. Complementing recent research on indigenous sovereignty in the islands, it applies the analytical prisms of plantation polity and racialization to interrogate planter-ruling elite mediation in the contingent transition from a native- to migrant-dominated plantation labor force. Drawing on close engagement with the institutional, discursive, and operational archives of planters in Hawai‘i in the decades preceding US annexation, including Kingdom government records, an emergent Hawai‘i-based planter press, and planter correspondence, this chapter emphasizes how the plantation and planter networking figured in the contested and variegated state formation processes of late nineteenth-century Hawai‘i.
Simulating University Application Data for Fair Matchings
Authors: Segal Meirav , George Anne-Marie , Dimitrakakis Christos 
Published: February 2023

AbstractThis paper describes the design of a simulator (work in progress), that is based on Norwegian university admissions and exam data. It generates a realistic population of applicants to university programs, their preferences and study outcomes if they were admitted to the different study programs. This simulator is a versatile tool and can be used to analyse the current admission policy for Norwegian universities in terms of many fairness criteria that, e.g., take into account student preferences, gender balance, university preferences and study outcomes. More generally, it creates a benchmark for testing matching algorithms and fairness notions without revealing sensitive data.
BCF anomaly and higher-group structure in the low energy effective theories of mesons
Authors: Nakajima Tatsuki , Sakai Tadakatsu , Yokokura Ryo 
Published: February 2023

Abstract
We discuss the BCF anomaly of massless QCD-like theories, first obtained by Anber and Poppitz, from the viewpoint of the low energy effective theories. We assume that the QCD-like theories exhibit spontaneous chiral symmetry breaking due to a quark bilinear condensate. Using the ’t Hooft anomaly matching condition for the BCF anomaly, we find that the low energy effective action is composed of a chiral Lagrangian and a Wess-Zumino-Witten term together with an interaction term of the η′ meson with the background gauge field for a discrete one-form symmetry. It is shown that the low energy effective action cancels the quantum inconsistencies associated with η′ due to an ambiguity of how to uplift the action to a five-dimensional spacetime with a boundary. The η′ term plays a substantial role in exploring the emergent higher-group structure at low energies.
Incidence, predictors and vascular sequelae of distal limb ischemia in minimally invasive cardiac surgery with femoral artery cannulation: an observational cohort study
Authors: Ceulemans Angelique , Derwael Ruben , Vandenbrande Jeroen , Buyck Katelijne , Gruyters Ine , Van Tornout Michiel , Murkin John M. , Starinieri Pascal , Yilmaz Alaaddin , Stessel Björn 
Published: February 2023

AbstractLiterature regarding monitoring and consequences of distal limb ischemia due to femoral artery cannulation for Minimally Invasive Cardiac Surgery (MICS) remains limited. The primary objective was to determine its incidence, defined as a ≥ 15% difference in regional Oxygen Saturation (rSO2) lasting ≥ four consecutive minutes between the cannulated and non-cannulated limb. The secondary objectives included: determination of distal limb ischemia, defined as a Tissue Oxygenation Index (TOI) < 50% in the cannulated limb, identification of predictors for distal limb ischemia, determination of a possible association of NIRS-diagnosed ischemia with acute kidney injury, and the need for vascular surgery up to six months after cardiac surgery. A prospective, observational cohort study with blinded rSO2-measurements to prevent intraoperative clinical decision-making. A single-center, community-hospital, clinical study. All consecutive patients ≥ 18 years old, and scheduled for predefined MICS. Patients underwent MICS with bilateral calf muscle rSO2-measurements conducted by Near-Infrared Spectroscopy (NIRS). In total 75/280 patients (26.79%) experienced distal limb ischemia according to the primary objective, while 18/280 patients (6.42%) experienced distal limb ischemia according to the secondary objective. Multivariate logistic regression showed younger age to be an independent predictor for distal limb ischemia (p = 0.003). None of the patients who suffered intraoperative ischemia required vascular surgery within the follow-up period. The incidence of NIRS-diagnosed ischemia varied from 6.4% to 26.8% depending on the used criteria. Short and long-term vascular sequelae, however, are limited and not intraoperative ischemia related. The added value of intraoperative distal limb NIRS monitoring for vascular reasons seems limited. Future research on femoral artery cannulation in MICS should shift focus to other outcome parameters such as acute kidney injury, postoperative pain or paresthesias.
Comparing models of information transfer in the structural brain network and their relationship to functional connectivity: diffusion versus shortest path routing
Authors: Neudorf Josh , Kress Shaylyn , Borowsky Ron 
Published: February 2023

AbstractThe relationship between structural and functional connectivity in the human brain is a core question in network neuroscience, and a topic of paramount importance to our ability to meaningfully describe and predict functional outcomes. Graph theory has been used to produce measures based on the structural connectivity network that are related to functional connectivity. These measures are commonly based on either the shortest path routing model or the diffusion model, which carry distinct assumptions about how information is transferred through the network. Unlike shortest path routing, which assumes the most efficient path is always known, the diffusion model makes no such assumption, and lets information diffuse in parallel based on the number of connections to other regions. Past research has also developed hybrid measures that use concepts from both models, which have better predicted functional connectivity from structural connectivity than the shortest path length alone. We examined the extent to which each of these models can account for the structure–function relationship of interest using graph theory measures that are exclusively based on each model. This analysis was performed on multiple parcellations of the Human Connectome Project using multiple approaches, which all converged on the same finding. We found that the diffusion model accounts for much more variance in functional connectivity than the shortest path routing model, suggesting that the diffusion model is better suited to describing the structure–function relationship in the human brain at the macroscale.
Association between adjuvant therapy and survival in colorectal cancer patients according to metabolic Warburg-subtypes
Authors: Offermans Kelly , Jenniskens Josien C. A. , Simons Colinda C. J. M. , Samarska Iryna , Fazzi Gregorio E. , Smits Kim M. , Schouten Leo J. , Weijenberg Matty P. , Grabsch Heike I. , van den Brandt Piet A. 
Published: February 2023

Abstract
Purpose
Tumor location and tumor node metastasis (TNM) stage guide treatment decisions in colorectal cancer (CRC) patients. However, patients with the same disease stage do not benefit equally from adjuvant therapy. Hence, there remains an urgent clinical need to identify prognostic and/or predictive biomarker(s) to personalize treatment decisions. In this exploratory study, we investigated whether our previously defined metabolic Warburg-subtypes can predict which CRC patients might derive survival benefit from adjuvant therapy.

Methods
Information regarding treatment (surgery only: n = 1451; adjuvant radiotherapy: n = 82; or adjuvant chemotherapy: n = 260) and Warburg-subtype (Warburg-low: n = 485, -moderate: n = 641, or –high: n = 667) was available for 1793 CRC patients from the Netherlands Cohort Study (NLCS). Kaplan–Meier curves and Cox regression models were used to investigate survival benefit from adjuvant therapy compared to surgery-only for the different Warburg-subtypes.

Results
Patients with Warburg-moderate CRC (HRCRC-specific 0.64; 95% CI 0.47–0.86, HRoverall 0.61; 95% CI 0.47–0.80), and possibly Warburg-high CRC (HRCRC-specific 0.86; 95% CI 0.65–1.14, HRoverall 0.82; 95% CI 0.64–1.05), had survival benefit from adjuvant therapy. No survival benefit was observed for patients with Warburg-low CRC (HRCRC-specific 1.07; 95% CI 0.76–1.52, HRoverall 0.95; 95% CI 0.70–1.30). There was a significant interaction between Warburg-subtype and adjuvant therapy for CRC-specific survival (p = 0.049) and overall survival (p = 0.035).

Conclusion
Our results suggest that Warburg-subtypes may predict survival benefit from adjuvant therapy in CRC patients. A survival benefit from adjuvant therapy was observed for patients with Warburg-moderate and possibly Warburg-high CRC, but not for patients with Warburg-low CRC. Future prospective studies are necessary to validate our findings.
Oral health-related quality of life and patient-reported outcome measures after 10 years of supportive periodontal care
Authors: Vogt Luca , Pretzl Bernadette , Eickholz Peter , Ramich Tatjana , Nickles Katrin , Petsos Hari 
Published: February 2023

Abstract
Objective
The aim of this retrospective study was to evaluate the oral health-related quality of life (oHRQoL) and patient-reported outcome measures (PROMs) after 10 years of supportive periodontal care (SPC).

Material and methods
Patients were re-examined 120±12 months after active periodontal therapy. Dental and periodontal status and oHRQoL by completing Oral Health Impact Profile-G49 (OHIP-G49) and PROMs by marking a visual analogue scale (VAS) for self-perceived esthetics (VASe), chewing function (VASc), and hygiene ability (VASh) were assessed. Patient- and tooth-related factors (age, insurance status, number of SPC, compliance, change of therapist, smoking, tooth loss, need for surgery or antibiotic intake, bleeding on probing (BOP), periodontal inflamed surface area) influencing oHRQoL and PROMs were evaluated.

Results
One hundred eight periodontally compromised patients (59 female, mean age 65.4±10.7 years) lost 135 teeth during 10 years of SPC. At re-examination, 1.8% of all sites showed PPD ≥6mm. The mean OHIP-G49 sum score was 17.6±18.5, and VAS resulted in 76.0±22.5 (VASe), 86.3±16.3 (VASc), and 79.8±15.8 (VASh). Linear regression analyses identified a positive correlation with oHRQoL and/or PROMs for private insurance status (OHIP-G49, p=0.015, R2=0.204; VASc, p=0.005, R2=0.084; VASh, p=0.012, R2=0.222) and compliance to SPC (VASe, p=0.032; R2=0.204), as well as a negative correlation for active smoking (VASc, p=0.012, R2=0.084), increased BOP (VASh, p=0.029, R2=0.222) at the start of SPC, and number of lost molars (VASh, p=0.008, R2=0.222).

Conclusion
It is realistic to obtain satisfactory oHRQoL and PROM values in most of the patients after 10 years of SPC. The identified factors may help to predict patient satisfaction in the long-term course of therapy.

Clinical relevance
Systematic therapy of periodontally compromised patients provides values for oHRQoL and PROMs in a favorable range 10 years after therapy. This should encourage dentists to implement SPC in their daily routine.

Clinical trial number
NCT03048045
Preservation of long-term memory in older adults using a spaced learning paradigm
Authors: Caffrey Michelle , Commins Sean 
Published: February 2023

AbstractHow much information we retain depends on type/schedule of training. It has been widely acknowledged that spaced learning is advantageous compared to massed learning for cognitively healthy young adults and should be considered an educational standard. Literature would suggest that the spacing effect is preserved with age, though it is unclear whether this effect translates to more ecologically valid concepts such as face-name associations, which are particularly susceptible to deterioration with age. Two experiments were conducted to investigate the effects of spacing across recent/remote retention intervals, and the effect of age on spacing in cognitively healthy older adults using the Face-Name Pairs task. Experiment 1 results suggest that the beneficial memory effects of spacing are particularly observed with long-term memory. Experiment 2 results suggest that older adults are impaired at learning compared to younger adults, that the spacing effect influences both older and younger adults at longer intervals, and that spaced-trained participants display similar forgetting patterns at longer intervals, irrespective of age. These results may have some implications regarding improving the conditions under which optimum retention occurs (namely, whether spacing is beneficial when learning ecologically valid concepts at longer intervals outside of laboratory settings), and may provide insight into the effect of age on our ability to learn and remember face-name associations.
Effects of Economic Capital, Cultural Capital and Social Capital on the Educational Expectation of Chinese Migrant Children
Authors: Ding Qifan , Wu Qiaobing 
Published: February 2023

AbstractThe barrier for Chinese migrant children to receive compulsory education in megacities has been gradually solved in recent years. The demand for senior high school education is now the bottom line for most of migrant children. Unlike compulsory education, high school education in China is a prerequisite for students to enter university and can profoundly affect their future decisions. This study aims to identify how various dimensions of economic, cultural and social capital embedded in the family, school and peer contexts influence the educational expectation of Chinese migrant children. The study results showed that all dimensions of capital significantly influenced the educational expectation of migrant children except family social capital. The effect of objectified cultural capital appeared to be the most predominant factor. Surprisingly, against the original hypothesis, economic capital and embodied cultural capital negatively influenced educational expectations.
Invisible (bio)economies: a framework to assess the ‘blind spots’ of dominant bioeconomy models
Authors: Pungas Lilian 
Published: February 2023

AbstractBioeconomy as a new promissory discourse neither challenges the paradigm of economic growth, nor questions its embeddedness in capitalist (neo-)colonial patriarchal power relations. However, the calls for a ‘genuine’ socio-ecological transformation and for alternative bioeconomy visions imply exactly a destabilization of these power relations. Drawing on the Bielefeld subsistence approach and on its colonialism–capitalism–patriarchy nexus, I argue that the latest bioeconomy strategy and policy papers of both the EU and Estonia each disregard certain spheres of the bioeconomy due to the three-dimensional power relations. As a seemingly neutral political discourse, the bioeconomy is shaped by cultural assumptions and narratives that determine and perpetuate what is deemed worthy of protection and what is pushed aside as merely ‘natural’. As such, the current bioeconomy papers promote a ‘biomass-based model of capital accumulation’ that is essentially built on the prerequisite of the subordination, devaluation, appropriation and/or exploitation of (1) different geographical regions, (2) ecological foundations, and (3) prevalent bioeconomy practices. As a widespread agricultural practice in Eastern Europe, Food Self-Provisioning (FSP) serves as a good example of how predominant bioeconomy models (1) simply operate as new forms of postcolonial development discourse, instead of embracing the plurality of decolonial ‘alternatives to development’; (2) deepen the human–nature dichotomy by regarding nature as a mere resource to be extracted more efficiently instead of cultivating mutually nourishing partnership-like relation(ship)s with nature; and (3) maintain the separation between monetized and maintenance economies, rather than fostering ethics of care to overcome the structural separation between the latter.
What is attractive rural landscape? Differences in the social and expert assessment of the changes in the rural landscape of the Carpathian region in Poland with regard to the need of its protection
Authors: Gajdek Agata , Krupa Barbara , Nowak Anna 
Published: February 2023

AbstractContemporary villages of the mountain region are subject to uncontrolled structural and spatial transformations, which cause deformation of centuries-old spatial systems of high cultural and natural value. The aim of the study is to confront the opinions of the inhabitants and experts regarding the condition of the cultural landscape of the villages in south-eastern Poland. This area belongs to the Carpathian region of Central Europe. The historical and economic conditions of the studied region, related to the functioning in the post-war period, and then its breakdown and the development of the free market economy, constitute an interesting background for the proposed research. Local communities still remembering the period of difficulties related to the period of systemic transformations, are currently experiencing a relative prosperity, many difficulties related to the period of systemic transformations, are currently experiencing a relative prosperity, which is also expressed in a completely new, previously unknown way of managing the landscape. Investments implemented in villages are associated by the inhabitants with the improvement of the standards and quality of life. They assess them rather positively. An expert assessment of these landscape transformations indicates their negative dimension and the risk of losing timeless values. The discrepancy in the assessment of experts and local residents creates difficulties in the protection of the rural landscape. Therefore, high-quality visual landscape features among rural residents is necessary from the point of view of its multi-faceted and effective protection. Local initiatives and actions in the field of industry policy should play a significant role in this respect by consolidating the images of a harmonious landscape in the public awareness.