bluuebunny/crossref_metadata_2025_split huggingface dataset:
Barriers and facilitators of access to sexual and reproductive health services among migrant, internally displaced, asylum seeking and refugee women: A scoping review
Authors: Sawadogo Pengdewendé Maurice , Sia Drissa , Onadja Yentéma , Beogo Idrissa , Sangli Gabriel , Sawadogo Nathalie , Gnambani Assé , Bassinga Gaëtan , Robins Stephanie , Tchouaket Nguemeleu Eric 
Published: September 2023

Introduction
Migrant, internally displaced, asylum seeking and refugee women experience ongoing risks of having their reproductive healthcare rights violated. This ever-increasing population also has limited access to sexual and reproductive health services. We conducted a scoping review to identify the barriers and facilitating factors when accessing sexual and reproductive health services for this specific population.

Methods
We searched the grey literature and queried eight bibliographic databases (Embase, Medline, Cinahl, Scopus, Science Direct, Web of Science, Hinari, and Cochrane Library) to extract articles published between January, 2000, and October, 2021. The extracted data were organized in a framework adapted from Peters et al. and then categorized as facilitators or barriers. We followed the Arksey and O’Malley framework and wrote the report according to the PRISMA-Scr recommendations.

Results
The search identified 4,722 records of which forty-two (42) met eligibility criteria and were retained for analysis. Ten (10) groups of factors facilitating and/or limiting access to sexual and reproductive health care emerged from the synthesis of the retained articles. The main barriers were lack of knowledge about services, cultural unacceptability of services, financial inaccessibility, and language barriers between patients and healthcare providers. Facilitators included mobile applications for translation and telehealth consultations, patients having a wide availability of information sources, the availability health promotion representatives, and healthcare providers being trained in cultural sensitivity, communication and person-centered care.

Conclusion
Ensuring the sexual and reproductive rights of migrant, internally displaced, asylum-seeking and refugee women requires that policymakers and health authorities develop intervention strategies based on barriers and facilitators identified in this scoping review. Therefore, considering their mental health in future studies would enable a better understanding of the barriers and facilitators of access to sexual and reproductive health services.
Retrospective analysis of real-world data to evaluate actionability of a comprehensive molecular profiling panel in solid tumor tissue samples (REALM study)
Authors: Leroy Karen , Audigier Valette Clarisse , Alexandre Jérôme , Boussemart Lise , Chiesa Jean , Deldycke Clotilde , Gomez-Rocca Carlos , Hollebecque Antoine , Lehmann-Che Jacqueline , Lemoine Antoinette , Mansard Sandrine , Medioni Jacques , Monnet Isabelle , Mourah Samia , Pierret Thomas , Spaëth Dominique , Civet Alexandre , Galoin Sandrine , Italiano Antoine 
Published: September 2023

Introduction
Considering the growing interest in matched cancer treatment, our aim was to evaluate the ability of a comprehensive genomic profiling (CGP) assay to propose at least one targeted therapy given an identified genomic alteration or signature (actionability), and to collect the treatment modifications based on the CGP test results in clinical practise for solid tumors.

Methods
This retrospective, multicentre French study was conducted among 25 centres that participated in a free of charge program between 2017 and 2019 for a tissue CGP test. Data were collected on the patient, disease, tumor genomic profile, treatment suggested in the report (related to the genomic profile results) and subsequent therapeutic decisions according to the physician’s declaration.

Results
Among the 416 patients, most had lung cancer (35.6%), followed by biliary tract cancer (11.5%) or rare cancers (11.1%); 75% had a metastatic disease. The actionability was 75.0% (95% CI [70.6%-78.9%]) for all patients, 85.1% and 78.4%, respectively in lung cancer and metastatic patients. After exclusion of clinical trial suggestions, the actionability decreased to 62.3% (95% CI [57.5%-66.8%]). Treatment modification based on the test results was observed in 17.3% of the patients and was more frequent in metastatic disease (OR = 2.73, 95% CI [1.31–5.71], p = 0.007). The main reasons for no treatment modification were poor general condition (33.2%) and stable disease or remission (30.2%). The genomic-directed treatment changes were performed mostly during the first six months after the CGP test, and interestingly a substantial part was observed from six to 24 months after the genomic profiling.

Conclusion
This French study provides information on the real-life actionability of a CGP test based on tissue samples, and trends to confirm its utility in clinical practice across the course of the disease, in particularly for patients with lung cancer and/or advanced disease.
The influence of hip revision stem spline design on the torsional stability in the presence of major proximal bone defects
Authors: Boettcher Julius M. , Sellenschloh Kay , Huber Gerd , Ondruschka Benjamin , Morlock Michael M. 
Published: September 2023

Background
Despite the success of primary total hip arthroplasty, the number of revisions remains high. Infection, aseptic loosening, periprosthetic fractures and dislocations are the leading causes of hip revision. Current revision stem designs feature a tapered body with circumferential placed longitudinal thin metal splines that cut into the femoral cortex of the diaphysis to provide axial and rotational stability. Modifications to the spline design may help improve primary stability in various bone qualities. The purpose of this study was to evaluate whether the rotational stability of a revision hip stem can be improved by an additional set of less prominent, wider splines in addition to the existing set of splines. It is hypothesized that the additional splines will result in greater cortical contact, thereby improving torsional strength.

Methods and findings
The ultimate torsional strength of an established modular revision stem (Reclaim®, DePuy Synthes) was compared to a Prototype stem design with two sets of splines, differing in prominence by 0.25 mm. Five pairs of fresh-frozen human femurs (n = 10) were harvested and an extended trochanteric osteotomy was performed to obtain common bone defects in revision. Stems were implanted using successive droptower impacts to omit variability caused by mallet blows. The applied energy was increased from 2 J in 1 J increments until the planned implantation depth was reached or seating was less than 0.5 mm at 5 J impact. The ultimate torsional strength of the bone-to-implant interface was determined immediately after implantation. Image superposition was used to analyze and quantify the contact situation between bone and implant within the femoral canal. Cortical contact was larger for the Prototype design with the additional set of splines compared to the Reclaim stem (p = 0.046), associated with a higher torsional stability (35.2 ± 6.0 Nm vs. 28.2 ± 3.5 Nm, p = 0.039).

Conclusions
A second set of splines with reduced prominence could be shown to improve primary stability of a revision stem in the femoral diaphysis in the presence of significant proximal bone loss. The beneficial effect of varying spline size and number has the potential to further improve the longevity of revision hip stems.
Psychometric properties of the Problematic Use of Social Networks (PUS) scale in Arabic among adolescents
Authors: Obeid Sahar , González-Nuevo Covadonga , Postigo Álvaro , El Dine Abir Sarray , Azzi Vanessa , Malaeb Diana , Hallit Souheil 
Published: September 2023

Background
The Problematic Use of Social Networks (PUSN) scale assesses for the first time the comparative use of social networks along with addictive tendencies. However, it has only been validated in a Spanish sample. This study aimed to evaluate the psychometric properties of the Arabic version of the PUSN (PUSN-Ar) among Lebanese adolescents.

Methods
A total of 379 adolescents aged between 15 to 18 years (M = 16.07 years; 64.9% females) participated in this cross-sectional study conducted between January and May 2022. The problematic use of social networks—SNS (PUSN) scale yields of two subscales: addiction-related consequences of SNS use (SNS-ARC) and negative social comparison (SNS-NSC). The Beirut Distress Scale, the Smartphone Addiction Scale and the Jong-Gierveld Loneliness Scale were used to assess psychological distress, smartphone addiction and loneliness respectively.

Results
The PUS-Ar scale exhibited a two-dimensional structure (Comparative Fit Index [CFI] = .97; Root Mean Square Error of Approximation [RMSEA] = .08), consistent with the original scale. Both subscales, Negative Social Comparison (α = .96) and Addictive Consequences (α = .92), demonstrated excellent reliability. Additionally, measurement invariance was verified between males and females at the configural, metric and scalar levels. No significant difference was found between males and females in terms of SNS-NSC (20.75 ± 10.15 vs 21.09 ± 9.51; t(377) = -.32; p = .751) and SNS-ARC (19.08 ± 8.61 vs 19.76 ± 6.77; t(377) = -.79; p = .430). The SNS-ARC subscale was more correlated to smartphone addiction than the SNS-NSC (r = .73; p < .001 vs r = .54; p < .001) whereas both subscales were significantly associated with more stress and more loneliness.

Conclusion
The data collected in this study provided support for all the hypotheses formulated. Consequently, the PUS-Ar was deemed a suitable scale to measure problematic SNS among Lebanese adolescents. The PUS-Ar is currently available to researchers for use in evaluating PSNSU in Lebanon. However, it is important to note that further research is needed to explore its applicability and generalizability across different populations and contexts.
The Reaction of Portuguese SMEs in the Face of the Covid-19 Crisis
Authors: Stefani Silvio Roberto , Teixeira Josélia Elvira 
Published: September 2023

Purpose of the study: this study analyzes the micro, small, and medium enterprises SMEs’ reaction toward public policies to support domestic companies during the period of lockdown in Portugal. Methodology/approach: the research used a weekly survey conducted by Statistics Portugal in partnership with Banco de Portugal. The survey, was developed to monitor the impact of the pandemic on companies and this study analyzes the results of the survey. Main results: the survey indicated that the companies most affected by the lockdown were micro-enterprises, mainly in the hospitality and restaurant industry. However, 82.3% of SMEs completely or partially continued to perform their activities during the lockdown. Most businesses were not planning to use government support mechanisms such as access to credit at lower interest rates. Nevertheless, more than a hundred thousand companies used the instrument of simplified layoffs made available by the government to suspend workers’ contracts. Theoretical/methodological contributions: the study shows that contrary to the expectations of the policymakers, most SMEs did not use credit as a support tool to overcome the pandemic, among the other support policies the most used was the suspension of payment of tax. Relevance/originality: this study is valuable because it allows the analysis of what types of public policies can lead small businesses to cope with the crisis caused by Covid-19. Social / management contributions: the study also contributes by demonstrating whether the formulation and implementation of public policy can impact small businesses, but policy design has often not effectively reached its target audience.
Theoretical investigation on the elastic and mechanical properties of high-entropy alloys with partial replacement of Sc in Hf0.25Ti0.25Zr0.25Sc0.25−x
Al
x
(x ≤ 15 %)
Authors: Maddheshiya Ajit Kumar , Singh Shakti Pratap , Singh Devraj , Yadav Phool Singh , Yadav Raja Ram , Yadav Thakur Prasad 
Published: September 2023

Abstract
The theoretical assessment of mechanical and elastic properties is used to analyze the distinctive properties of high entropy alloys (HEAs) at room temperature. Using Lennard–Jones potential model, the second order elastic constants (SOECs) and third order elastic constants (TOECs) have been determined for the HEAs Hf0.25Ti0.25Zr0.25Sc0.25−x
Al
x
(x ≤ 15 %) in their hexagonal close-packed (hcp) phases. SOECs have been used to calculate mechanical constants, Poisson’s ratio, Pugh’s ratio, Kleinman’s parameter. In order to determine the anisotropic behaviour of the selected HEAs, the elastic anisotropy has also been computed at room temperature. All the HEAs under consideration have anisotropy parameters that are not equal to one, indicating anisotropic behaviour. Later, the Grüneisen parameters were estimated for the chosen HEAs Hf0.25Ti0.25Zr0.25Sc0.25−x
Al
x
(x ≤ 15 %) along longitudinal and shear modes of wave propagation. Analysis of the research results reveals the inherent properties of HEAs.
Corporate Venturing in Deutschland und den USA
Authors: Sandikçi Süleyman , Metzler Jannik 
Published: September 2023

Abstract
Viele etablierte Unternehmen kooperieren im Rahmen von Corporate Venturing mit Start-ups, um einen Zugang zu neuen Technologien zu erhalten, neue Geschäftsfelder aufzubauen und Innovationen hervorzubringen. Der Großteil der in DAX und Dow Jones vertretenen Unternehmen, darunter auch zahlreiche produzierende Unternehmen, verfügt über Venture-Einheiten, die die Zusammenarbeit initiieren und steuern. Dieser Beitrag liefert auf Grundlage statistischer Daten Erkenntnisse zur Bedeutung von Start-up-Zentren und zur lokalen Präferenz von Venture-Einheiten in Deutschland und den USA.
Repertórios de luta de mulheres latino-americanas durante a pandemia
Authors: Sartorio Gonçalves Lara , Silva Reghim Mariane , Gonzalez Vitória 
Published: September 2023

O protagonismo das mulheres e dos múltiplos feminismos latino
-
americanos ao longo da
pandemia caracterizam a luta popular do período. Observamos um processo inventivo e
multiplicador de repertórios mobilizados com acentuado giro decolonial. O propósito des
te
trabalho consistiu em tratar da trajetória dos movimentos feministas na América Latina,
apontando a emergência de diferentes repertórios em processos de continuidade, ruptura e
atualização. A partir desse desenvolvimento socio
-
histórico, teórico e da an
álise de dados
contidos nos monitoramentos de movimentos sociais em diferentes países da região, que
realizamos no bojo das iniciativas do Observatório de Movimentos Sociais na América Latina
(OMSAL), chegamos a conclusões interessantes: (a) os repertórios
de ação dos movimentos
feministas escancararam elementos cruciais para compreender o período da pandemia no
continente e seus impactos na vida social e política; (b) a vida das mulheres, sobretudo das
mulheres negras, sofreu impacto diferenciado da pandem
ia em diferentes temáticas; (c) o
cenário global de crescente autoritarismo, militarização, ascensão de extrema direita e de um
forte discurso antifeminista e nostálgico de períodos ditatoriais tornou o feminismo alvo de
resistência central; (d) a dinâmica
de afeto dos movimentos feministas reconstrói vínculos
sociais e ações de solidariedade.
Território, autonomia, soberania e extrativismo
Authors: Trotte Alyssa , Lopes Deborah , Closs Marília 
Published: September 2023

Este artigo tem como objetivo analisar os conflitos socioambientais TIPNIS, Chepete
-
El Bala e
da extração de lítio na Bolívia durante o período de pandemia da Covid
-
19, tendo como
recorte temporal abril de 2020 a abril de 2022. Para mapear os confli
tos, orientamo-nos pelas
seguintes perguntas: i) Quais foram os atores envolvidos nos conflitos? ii) Quais demandas
por eles pautadas? e iii) Como essas demandas foram reivindicadas na pandemia? Em termos
metodológicos, utilizamos fontes secundárias (jorna
is e meios de comunicação alternativos) e
mapeamento das redes sociais dos movimentos envolvidos nos casos estudados. À luz da
discussão contemporânea sobre extrativismo e neoextrativismo na América Latina,
concluímos que, durante a pandemia, há uma manute
nção nos padrões de relação Estado-recursos naturais por parte do governo, inalterados inclusive com as transições de governo
entre 2020 e 2021. Verifica-se, no entanto, que dentro das mesmas gramáticas de autonomia
e luta pelos territórios há um novo repe
rtório de ação sendo criado, com transformações nas
formas de reivindicação por parte dos atores sociais.
Creatividad, danza e indagación social
Authors: Paula Zanin María 
Published: September 2023

El presente escrito busca adentrarse en algunos debates de la teoría sociológica que aportan
herramientas heurísticas como ejercicio reflexivo intrínseco para repensar los problemas de
investigación específicos. El objetivo es indagar sobre los fundamentos
de por qué la dimensión
creativa de la acción es clave para abordar la danza como práctica artística/expresiva colectiva.
En un primer apartado se pone en contexto y tensión el planteo teórico del sociólogo Hans Joas
en torno a la dimensión creativa de la
acción enfatizando su influencia pragmatista, sus aportes y
limitaciones en el marco del desarrollo de la teoría sociológica. Luego se introduce la danza como
práctica abordada desde lo social, dando cuenta de algunos antecedentes relevantes de
investigac
iones que la abordan y permiten indagar sobre los distintos lentes teóricos y
epistémicos utilizados en su análisis. Por último, como cierre del trabajo, se tensiona, en el marco
de la teoría sociológica contemporánea, algunos hallazgos, para abordar la da
nza desde la
creatividad y la expresividad como claves analíticas
Increasing COVID-19 Vaccination Rates for Children With Sickle Cell Disease
Authors: Yan Adam P. , Archer Natasha M. , Arnold Dianne , Hansbury Eileen , Heeney Matthew M. , Johnson David , Lichtman Erica , McMullan Heather , Morrissey Lisa , Ilowite Maya 
Published: September 2023

BACKGROUND
The COVID-19 vaccine is important for children with sickle cell disease (SCD). This quality improvement project's objective was to increase the proportion of children with SCD receiving ≥2 COVID-19 vaccine doses to ≥70% by June 2022.

METHODS
We used the Model for Improvement framework. We assessed COVID-19 vaccination rates biweekly. Three plan-do-study-act cycles focusing on patient education, provider awareness, and access were performed. Process measures included the outcome of outreach calls and educational video views. Missed clinic appointments was our balancing measure. Line graphs and statistical process control charts were used to track changes. Interrupted time series was used to model implementation rates while accounting for preexisting trends.

RESULTS
A total of 243 patients were included. During the preintervention (September 2021–January 2022) and intervention periods (February 2022–June 2022), overall vaccination rates increased from 33% to 41% and 41% to 64%, respectively. Mean vaccination rate in eligible children in each 2-week period increased from 2.1% to 7.2%. The achieved vaccination rate was 11% greater than predicted for patients with SCD. For the general population the achieved vaccination rate was 23% lower than predicted. The proportion of missed visits did not change (9.0% vs. 9.6%). During outreach calls, 10 patients (13.5%) booked a vaccine. Forty percent of patients watched the promotional video.

CONCLUSIONS
A significant number of patients with SCD are not vaccinated against COVID-19. Targeting misinformation and improving vaccine access aided in increasing vaccination. Additional interventions are needed as a large number of patients remain unvaccinated.
Methylcobalamin injection 1500 mcg SC route versus IM route: A randomized parallel comparative bioavailability study
Authors: Modi Nimesh P , Jaiswal Anil J , Vasu PNSS 
Published: September 2023

Corona Remedies developed B-29 AQ PFS (Methylcobalamin Injection 1500 mcg) SC route for better patient compliance and ease of administration. The study outcome will explain pharmacokinetic behaviour of Methylcobalamin SC injection and non-inferiority over IM injection. The study was conducted to compare bioavailability, safety and tolerability of two different Methylcobalamin Injection formulation 1500 mcg with SC versus IM route. This was randomized, two treatment, parallel, comparative bioavailability study conducted on 24 normal, healthy, adult, human subjects. The dosage of the investigational product (IP) was given either as a 1500 mcg SC injection into the abdominal muscle or as an intramuscular injection into the gluteal muscle (buttock region) following an overnight fast of at least 10 hours. To assess the plasma concentrations of methylcobalamin, a number of blood samples were collected both before and after the injection. Maximum plasma concentration (C), time to maximum plasma concentration (T) and the area under the concentration-time curve (AUC) were compared. Pharmacokinetic (PK) parameters were statistically analysed using Statistical Analysis Software (SAS) Version 9.4 or above. The mean T for methylcobalamin absorption from SC administration and IM injection was 1.38 hours and 1.49 hours, respectively. In terms of bioavailability, the SC injection is comparable to the IM injection (the ratio of population geometric means for the SC and IM routes is 103.62 for AUC). In this study, a higher C for the SC route than the IM route was found (57.01 versus 45.82). Based on log transformed primary PK parameters (C and AUC), the geometric least squares mean ratio was observed &#62;80.00%. According to safety evaluations, both therapies were safe and well-tolerated.Methylcobalamin is a safe and well-tolerated alternative to the current one that is non-inferior to IM route and faster in absorption after SC route.
Dirac equation solution in the light front via linear algebra and its particularities
Authors: Sales Jorge Henrique de Oliveira , Aragão Gabriel de Oliveira , Nascimento Diego Ramos do , Thibes Ronaldo 
Published: September 2023

In undergraduate and postgraduate courses, it is customary to present the Dirac equation defined in a space of four dimensions: three spatial and one temporal. This article discusses aspects of the Dirac equation (QED) on the light front. This proposal of coordinate transformations comes from Dirac who originally introduced three distinct forms of relativistic dynamics possible depending on the choice we make of the different hypersurfaces constant in time. The first he called instantaneous, the most common form, the hypersurface of which is specified by the boundary conditions set at . The second, known as the point form, has as its characterizing surface, a hyperboloid, described by the initial conditions in , being one constant (chosen as the time of this system). The third relativistic form, known as the light front form, has its hypersurface tangent to the light cone; being defined by the initial conditions at , and is the time in the light front system. The method of this work is deductive. Therefore, one obtains the solution of the Dirac equation for the Free Electron and for the positron in the coordinates in the light front with the particularity of the energy associated with the system being given by , and for moments we have the electron and we have the positron. The result of this is that the positive energy states in the light front and negative are independently described in the equation, and with additional, the problem at the limit that does not converge.