bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of endoscopic gastric plication on portosystemic pressure gradient in patients with nonalcoholic fatty liver disease and compensated advanced chronic liver disease
Authors: Jirapinyo Pichamol , Thompson Christopher C. , Garcia-Tsao Guadalupe , Zucker Stephen D. , Ryou Marvin 
Published: August 2023

Background The goals of therapy for patients with nonalcoholic fatty liver disease and compensated advanced chronic liver disease include weight loss and reduction of the portosystemic pressure gradient (PPG) to decrease the risk of hepatic decompensation. Endoscopic gastric plication (EGP) is an effective endoscopic weight loss procedure. This study aimed to assess the effect of EGP on PPG.
Methods In this prospective pilot study, patients with nonalcoholic fatty liver disease and compensated advanced chronic liver disease underwent endoscopic ultrasound-guided PPG measurement prior to and at 6 months following EGP. Primary outcomes were the change in PPG and proportion of patients experiencing ≥ 20 % reduction in PPG at 6 months. Secondary outcomes included percent total weight loss (TWL) and changes in noninvasive tests of fibrosis.
Results 20 patients were included. Baseline median body mass index and liver stiffness measurement were 40.2 kg/m2 (range 30.1–56.7) and 14.7 kPa (range 8.2–36), respectively. At 6 months, median PPG decreased from 5.4 mmHg (range 0.7–19.6) to 1.8 mmHg (range 0.4–17.6) (P = 0.002), with 79 % (11/14) experiencing ≥ 20 % reduction. Patients experienced 12.5 % (6.5 %–26.1 %) TWL (P < 0.001) at 6 months, with 89 % (17/19) achieving ≥ 7 % and 68 % (13/19) achieving ≥ 10 % TWL. There were significant improvements in noninvasive tests of fibrosis.
Conclusion EGP appeared to be effective at reducing PPG in patients with nonalcoholic fatty liver disease and compensated advanced chronic liver disease.
Application of the Heck Reaction for the Synthesis of C-Glycosyl Phenolic Compounds
Authors: Soengas Raquel G. , Silva Artur M. S. , Tomé Sara M. 
Published: August 2023

AbstractThe potential of the Heck reaction for the C-glycosylation of phenolic compounds was explored. An efficient and general methodology for the synthesis of C-glycosylated phenolic compounds based on the Heck coupling of halogenated phenolic derivatives (chromones, 2-styrylchromones, and xanthones) and sugar alkenes was developed. The protocol was applied to the preparation of previously unreported C-glycosylated 2-styrylchromones and xanthones of potential biological relevance.
Brain Expression of CPB2 and Effects of Cpb2 Deficiency in Mouse Models of Behavior
Authors: Meijers Joost C. M. , van der Harst Johanneke , Marx Pauline F. , Sahbaie Peyman , Clark David J. , Morser John 
Published: August 2023

Background Procarboxypeptidase B2 (proCPB2 or TAFI) is a zymogen that after activation cleaves C-terminal basic residues from peptides or proteins with many identified targets. A splice variant of CPB2 has been found in the brain lacking essential residues for its carboxypeptidase function. The aim was to determine CPB2 expression in the brain and effects of CPB2 deficiency (Cpb2
−/−) on behavior.
Materials and Methods Behavioral effects were tested by comparing Cpb2
−/− mice in short-term (open field and elevated zero maze tests) and long-term (Phenotyper) observations with wild-type (WT) controls.
Results Long-term observation compared day 1 (acclimatizing to novel environment) to day 4 (fully acclimatized) with the inactive (day) and active (night) periods analyzed separately. Brain expression of CPB2 mRNA and protein was interrogated in publicly available databases. Long-term observation demonstrated differences between WT and Cpb2
−/− mice in several parameters. For example, Cpb2
−/− mice moved more frequently on both days 1 and 4, especially in the normally inactive periods. Cpb2
−/− mice spent more time on the shelter and less time in it. Differences were more pronounced on day 4 after the mice had fully acclimatized. In short-term observations, no differences were observed between Cpb2
−/− mice and WT mice. Brain expression of CBP2 was not detectable in the human protein atlas. Databases of single-cell RNAseq did not show expression of CPB2 mRNA in either human or mouse brain.
Conclusion Continuous observation of home-cage behavior suggests that Cpb2
−/− mice are more active than WT mice, show different day–night activity levels, and might have a different way of processing information.
Septal Reconstruction: Simple to Complex
Authors: Oliver Jamie R. , Humphrey Clinton D. 
Published: August 2023

AbstractNasal septal deviation is a frequent problem treated by otolaryngologists and facial plastic surgeons. Complete correction of the septal deformity is often essential both for straightening a crooked nose and for restoration of the nasal airway. While standard septoplasty techniques provide excellent outcomes in most patients, severe septal deformities may require treatment with more advanced maneuvers including adjacent grafting, caudal septal replacement, and even extracorporeal septoplasty. This article reviews a range of septoplasty techniques, with an emphasis on complex septal reconstruction and approaches that can be utilized to maintain keystone stability and establish a robust midline L-strut even in cases with challenging anatomy.
Early Predictor of Acute Kidney Injury in Newborns with Perinatal Asphyxia
Authors: Refat Nafisa Hassan , Fathy Mohamed Amir , Hafez Ali Hamdy Ali Abdel , Sabra Mohammed Abdeltawab , Hamed Enas Ahmad , Abdelraheem Yasser Farouk 
Published: August 2023

AbstractAcute kidney injury (AKI) is an independent risk factor for neonatal death. Since neonatal early renal injury usually has no specific clinical symptoms, many AKI cases are often missed the best time of early intervention if there is no relevant examination. Perinatal asphyxia (PA) can lead to AKI. The study aimed to assess efficacy of serum cystatin C (CystC) in early prediction of AKI in full-term neonates with PA. The study was conducted at the neonatal intensive care unit, Assiut University Children Hospital from January 2019 to January 2021. Seventy full-term neonates with documented PA were enrolled in the study. Baseline laboratory data and serum CystC levels were assessed. Out of those 70 neonates with PA, 21 (30%) developed AKI, while 49 (70%) neonates did not develop AKI. Majority of non-AKI group had stage-I hypoxic-ischemic encephalopathy (HIE) (61.2%), while majority of AKI had stage-III HIE (61.9%). A significantly higher serum CystC level was found among AKI group than those without AKI (1.50 ± 0.12 vs. 0.90 ± 0.14, p < 0.001). The predictors for AKI among neonates with PA were low birth weight, serum CystC levels, hypotension, and stage-III HIE. Serum CystC has 94.3% overall accuracy for prediction of AKI. In conclusion, AKI in neonates with PA is common. CystC is a promising biomarker in early prediction of AKI in such cases. Future studies are warranted to confirm these findings.
A many-channel FPGA control system
Authors: Schussheim Daniel T. , Gibble Kurt 
Published: August 2023

We describe a many-channel experiment control system based on a field-programmable gate array (FPGA). The system has 16 bit resolution on 10 analog 100 megasamples-per-second (MS/s) input channels, 14 analog 100 MS/s output channels, 16 slow analog input and output channels, dozens of digital inputs and outputs, and a touchscreen display for experiment control and monitoring. The system can support ten servo loops with 155 ns latency and MHz bandwidths, in addition to as many as 30 lower bandwidth servos. We demonstrate infinite-impulse-response (IIR) proportional–integral–differential filters with 30 ns latency by using only bit-shifts and additions. These IIR filters allow timing margin at 100 MS/s and use fewer FPGA resources than straightforward multiplier-based filters, facilitating many servos on a single FPGA. We present several specific applications: Hänsch–Couillaud laser locks with automatic lock acquisition and a slow dither correction of lock offsets, variable duty cycle temperature servos, and the generation of multiple synchronized arbitrary waveforms.
Unfurling a rolled-up sheet from a dispenser at constant speed
Authors: Mungan Carl E 
Published: August 2023

Abstract
An introductory physics problem asks for the applied force necessary to pull a strip of paper towels off a mounted roll at a constant tangential speed. Numerous online help sites provide inadequate solutions. Newton’s second law for rotations can be applied as the radius and hence the moment of inertia decreases. Several rolls of flexible materials having different dimensions and masses are characterized to show that the required force can increase, remain constant, or decrease as time elapses for a roll that rotates frictionlessly about a fixed axle.
Effective Hamiltonian of magnetic moments in proximity with an s-wave superconductor
Authors: Shen S W , Zhang W , Shao L B 
Published: August 2023

Abstract
In this paper, we consider two magnetic moments in proximity with an s-wave superconductor, where each magnetic moment has an internal energy level. The effective Hamiltonian of the two magnetic moments is derived in this paper by the method of path integral in the weak coupling limit. Interestingly, there are four new terms by the proximity effect, including the Ruderman–Kittel–Kasuya–Yosida interaction, the hopping term, the cross and on-site superconducting pairing potentials. Additionally, since the parity of electrons is conserved, the Hilbert space is split into two subspaces of even and odd parities, respectively. We also investigate the consequences of the effective Hamiltonian in the Coulomb blockade regime by varying the distance between the two magnetic moments. We found that a quantum phase transition happens whenever there is a level crossing for the ground states. The degeneracy of the ground states is also changed after the quantum phase transition, and the electron occupations for the magnetic moments with both singlet and triplet states are discontinuous at the level crossing, since the electronic states are always entangled with the spin states of the two magnetic moments.
Polarization current effect, strain effect and ferroelectric field effect on electrical transport properties of Eu0.7Sr0.3MnO3/PMN-PT multiferroic heterostructure
Authors: Wang Shengnan , Zheng Ming , Wang Yi , Guo Xin , Chen Lu , Ni Hao 
Published: August 2023

Abstract
By constructing Eu0.7Sr0.3MnO3 thin films/0.7Pb(Mg1/3Nb2/3)O3-0.3PbTiO3 (001) multiferroic heterostructures, the electrical transport properties of the Eu0.7Sr0.3MnO3 thin film under electro-photo dual control is studied. At room temperature, as the in-plane reading current increases from 1 μA to 100 μA, the polarization current effect gradually weakens, while the strain effect becomes more evident. As the temperature decreases from 300 K to 240 K, the ferroelectric field effect is observed to strengthen progressively. In addition, by applying light illumination, the ferroelectric field effect observed at 240 K can be suppressed, which proves that the light field can obviously control the tunable mechanism of electric field. Our results demonstrate that the temperature and light field play an important role in the switching between the electric field induced multiple tunable effects, such as polarization current effect, lattice strain effect and ferroelectric field effect. Meanwhile, the sensitivity of the Eu0.7Sr0.3MnO3 film to lattice strain enhances its application in tunable electronics.
Automated characterization of spatial and dynamical heterogeneity in supercooled liquids via implementation of machine learning
Authors: Nguyen Viet , Song Xueyu 
Published: August 2023

Abstract
A computational approach by an implementation of the principle component analysis (PCA) with K-means and Gaussian mixture (GM) clustering methods from machine learning algorithms to identify structural and dynamical heterogeneities of supercooled liquids is developed. In this method, a collection of the average weighted coordination numbers (

W
C
N
s

‾

) of particles calculated from particles’ positions are used as an order parameter to build a low-dimensional representation of feature (structural) space for K-means clustering to sort the particles in the system into few meso-states using PCA. Nano-domains or aggregated clusters are also formed in configurational (real) space from a direct mapping using associated meso-states’ particle identities with some misclassified interfacial particles. These classification uncertainties can be improved by a co-learning strategy which utilizes the probabilistic GM clustering and the information transfer between the structural space and configurational space iteratively until convergence. A final classification of meso-states in structural space and domains in configurational space are stable over long times and measured to have dynamical heterogeneities. Armed with such a classification protocol, various studies over the thermodynamic and dynamical properties of these domains indicate that the observed heterogeneity is the result of liquid–liquid phase separation after quenching to a supercooled state.
Magnetoplasmons in magic-angle twisted bilayer graphene
Authors: Do Thi-Nga , Shih Po-Hsin , Gumbs Godfrey 
Published: August 2023

Abstract
The magic-angle twisted bilayer graphene (MATBLG) has been demonstrated to exhibit exotic physical properties due to the special flat bands. However, exploiting the engineering of such properties by external fields is still in it infancy. Here we show that MATBLG under an external magnetic field presents a distinctive magnetoplasmon dispersion, which can be significantly modified by transferred momentum and charge doping. Along a wide range of transferred momentum, there exist special pronounced single magnetoplasmon and horizontal single-particle excitation modes near charge neutrality. We provide an insightful discussion of such unique features based on the electronic excitation of Landau levels quantized from the flat bands and Landau damping. Additionally, charge doping leads to peculiar multiple strong-weight magnetoplasmons. These characteristics make MATBLG a favorable candidate for plasmonic devices and technology applications.
Investigations on thermal contact resistance between filled polymer composites and solids using micro thermography
Authors: Roser Oliver , Griesinger Andreas , Marti Othmar 
Published: August 2023

Abstract
This article reports the use of a new measurement technique based on micro thermography for determining the thermal contact resistances (TCRs) between filled polymers and solids. The thermal conductivity of polymers can be significantly increased by using thermally conductive fillers. For numerous applications, not only is a high intrinsic thermal conductivity required but also a good thermal transfer between the filled polymer and an adjacent solid surface. The physical principles of thermal transport when considering this type of contact have not yet been investigated in detail, and only a few experimental results are available. The most common measurement techniques determine a macroscopic resistance and project it onto the contacting surface. However, the heterogeneous microstructure of a filled polymer causes the TCR to be a volumetric phenomenon in the overall boundary region. The utilized IR camera system takes thermal images with a spatial resolution of less than

15
μ

m

per pixel. The new method resolves the TCRs spatially and gives new insights into the microscale effects on the particle level. In addition to the common zero-gap extrapolation for the extraction of TCRs, we propose another evaluation method that considers all microscale effects of the boundary layers and evaluates TCR as a volumetric phenomenon. For the first systematic study, samples consisting of two aluminum substrates and a filled epoxy polymer were prepared and investigated. We studied the effects of filler size, filler material, filler volume fraction, and surface structure, focusing on monomodally filled polymers with filler amounts between

30

and

60

v

%

. The obtained results and the uncertainties of the new method are discussed within this paper.
IPEM topical report: guidance for the clinical implementation of online treatment monitoring solutions for IMRT/VMAT
Authors: Stevens Simon , Moloney Stephen , Blackmore Andrew , Hart Clare , Rixham Philip , Bangiri Anna , Pooler Alistair , Doolan Paul 
Published: August 2023

Abstract
This report provides guidance for the implementation of online treatment monitoring (OTM) solutions in radiotherapy (RT), with a focus on modulated treatments. Support is provided covering the implementation process, from identification of an OTM solution to local implementation strategy. Guidance has been developed by a RT special interest group (RTSIG) working party (WP) on behalf of the Institute of Physics and Engineering in Medicine (IPEM). Recommendations within the report are derived from the experience of the WP members (in consultation with manufacturers, vendors and user groups), existing guidance or legislation and a UK survey conducted in 2020 (Stevens et al
2021). OTM is an inclusive term representing any system capable of providing a direct or inferred measurement of the delivered dose to a RT patient. Information on each type of OTM is provided but, commensurate with UK demand, guidance is largely influenced by in vivo dosimetry methods utilising the electronic portal imager device (EPID). Sections are included on the choice of OTM solutions, acceptance and commissioning methods with recommendations on routine quality control, analytical methods and tolerance setting, clinical introduction and staffing/resource requirements. The guidance aims to give a practical solution to sensitivity and specificity testing. Functionality is provided for the user to introduce known errors into treatment plans for local testing. Receiver operating characteristic analysis is discussed as a tool to performance assess OTM systems. OTM solutions can help verify the correct delivery of radiotherapy treatment. Furthermore, modern systems are increasingly capable of providing clinical decision-making information which can impact the course of a patient’s treatment. However, technical limitations persist. It is not within the scope of this guidance to critique each available solution, but the user is encouraged to carefully consider workflow and engage with manufacturers in resolving compatibility issues.
Cerebral blood velocity during concurrent supine cycling, lower body negative pressure, and head-up tilt challenges: implications for concussion rehabilitation
Authors: Burma Joel S , Seok Jina , Johnston Nathan E. , Smirl Jonathan D 
Published: August 2023

Abstract

Introduction. The effect of concurrent head-up tilt and lower body negative pressure (LBNP) have been examined on middle cerebral artery velocity (MCAv) at rest; however, it is unknown the superimposed effect these factors have on blunting the elevation in cerebral blood velocity associated with moderate-intensity exercise. Methods. 23 healthy adults (11 females / 12 males, 20–33 years) completed three visits. The first consisted of a maximal ramp supine cycling test to identify the wattage associated with individualized maximal MCAv. Subsequent visits included randomized no LBNP (control) or LBNP at −40 Torr (experimental) with successively increasing head-up tilt stages of 0, 15, 30, and 45 degrees during the pre-described individualized wattage. Transcranial Doppler ultrasound was utilized to quantify MCAv. Two-factorial repeated measures analysis of variance with effect sizes were used to determine differences between days and tilt stages. Results. Between-day baseline values for MCAv, heart rate, and blood pressure displayed low variability with <5% variation. With no LBNP, MCAv was above baseline on average for all participants; however, 15 degrees and 30 degrees tilt with concurrent −40 Torr LBNP was sufficient to return MCAv to 100% of baseline values in females and males, respectively. Body-weight did not impact the association between tilt and pressure (R
2 range: 0.01–0.12). Conclusion. Combined LBNP and tilt were sufficient to reduce the increase in MCAv associated with moderate-intensity exercise. This exercise modality shows utility to enable individuals with a concussion to obtain the positive physiological adaptions associated with exercise while minimizing symptom exacerbation due to the notion of the Monro-Kellie doctrine.
The electrical asymmetry effect in electronegative CF4 capacitive RF plasmas operated in the striation mode
Authors: Wang Xiao-Kun , Masheyeva Ranna , Liu Yong-Xin , Hartmann Peter , Schulze Julian , Donkó Zoltán 
Published: August 2023

Abstract
The Electrical Asymmetry Effect (EAE) provides control of the mean ion energy at the electrodes of multi-frequency capacitively coupled radio frequency plasmas (CCP) by tuning the DC self-bias via adjusting the relative phase(s) between the consecutive driving harmonics. Depending on the electron power absorption mode, this phase control affects the ion flux in different ways. While it provides separate control of the mean ion energy and flux in the α-mode, limitations were found in the γ- and Drift-Ambipolar modes. In this work, based on experiments as well as kinetic simulations, the EAE is investigated in the striation-mode, which is present in electronegative CCPs driven by low frequencies. The discharge is operated in CF4 and is driven by two consecutive harmonics (4/8 MHz). The simulation results are validated against measurements of the DC self-bias and the spatio-temporally resolved dynamics of energetic electrons. To include heavy particle induced secondary electron emission realistically, a new computationally assisted diagnostic is developed to determine the corresponding secondary electron emission coefficient from a comparison of the DC self-bias obtained experimentally and from the simulations. Based on the validated simulation results, the EAE is found to provide separate control of the mean ion energy and flux in the striation mode, while the axial charged particle density profiles and the number of striations change as a function of the relative phase. This is understood based on an analysis of the ionization dynamics.
Prediction of nodal-line fermion and phonon-mediated superconductivity in bilayer α-borophene
Authors: Ge Yanfeng , Wang Zhicui , Han Yifan , Shang Yue , Wan Wenhui , Liu Yong 
Published: August 2023

Abstract
The electron deficiency of boron allows the formation of a variety of monolayer or few-layer two-dimensional structures (borophenes) with interesting physical properties. Recent experiments have also confirmed that interlayer covalent bonding makes the bilayer structure more stable than the monolayer. In this work based on α-borophene, we propose three free-stranding bilayer structures with dynamic stability. In these three metallic structures, the electronic band crossings around Fermi level form nodal lines. All these structures also exhibit strong electron-phonon couplings. The Bardeen–Cooper–Schrieffer superconducting critical temperature T
c of the type-II structure went as high as 28.2 K, which was further improved to 32.0 K by the enhancement effect of Li adatom at the Debye frequency. However, no increase in critical temperature was observed in other Li-doping cases. Specifically, Li intercalation inside the bilayer causes a significant abrupt decrease in the critical temperature of type-I structure. Our results indicated that the bilayer borophene would be an ideal platform for the coexistence of topological electronic states and superconducting states.