bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neural Correlation of Relation Information——Evidence from ERP
Authors: Jia Xiaofei , Zhou Changle 
Published: April 2023

Abstract
Central-parietal N200 is an ERP component that associates with orthographic processing in Chinese word recognition. Studies have shown that it may be related to the early processing of morpheme structures. Compound words can be regarded as the smallest unit of morpheme combination, the recognition process can be analogous to the comprehension of the sentence, including combining constituent morphemes. This process includes grammatical combinations and semantic combinations. Studies have found that the semantic combination takes place during the N400 time-window. Generally speaking, the grammatical combination should occur before the semantic combination, so does the structure priming that occurred during the N200 time-window represent grammatical combination? We explored this issue by using Chinese coordinative compounds and ERP technology. We found that there is a significant grammatical structure priming effect in the processing of Chinese compound words. This effect occurs in the early stage of word processing, that is, the N200 period. Combined with the previous research, the semantic relation priming occurred in the N400 window, indicating that the grammatical combination did appear before the semantic combination, and outlined the time course of the effect of relation information.
Reported Self-Care Practice towards Prevention of Puerperal Sepsis and Associated Factors among Postnatal Mothers In Arba Minch Town, Southern Ethiopia, 2022
Authors: Mengistu Sheleme , Seyoum Kenbon , Temesgen Gebremaryam , Terefe Bezabih , Ejigu Neway , Kene Chala , Geta Girma 
Published: April 2023

Abstract
Background: Puerperal sepsis is an important cause of maternal morbidity and mortality, especially in developing countries including Ethiopia. If not identified early and preventive measures are not taken, it can lead to severe lifetime maternal morbidity and even death. So, to prevent maternal complications associated with puerperal sepsis, assessing the postnatal mother's self-care practice is vital. Therefore, this study aimed to assess reported self-care practices towards the prevention of puerperal sepsis and associated factors among postnatal mothers in Arba Minch town, southwest Ethiopia, 2022.
Methods: Community-based cross-sectional study was employed from may1-30th, 2022. A structured and interviewer-administered questionnaire was used to collect the data from study participants. Study participants were randomly selected and interviewed at their homes using simple random sampling techniques. The data was collected by Open Data Kit (ODK) and exported to the Statistical Package for Social Sciences (SPSS) version 26 for analysis and the information was presented using frequencies, summary measures, tables, and figures.
Both bivariate and multivariable logistic regression analyses were performed to identify associated factors. Pvalues < 0.05 with a 95% confidence level were used to declare statistical significance.
Results; A total of 417 postnatal mothers participated in this study making a response rate of 98.5%. The study revealed that 45.6% with (95%, CI (41.2% - 50.1%) of postnatal mothers had good self-care practice towards the prevention of puerperal sepsis, whereas the rest had poor self-care practice. Tertiary educational level (AOR = 2.56(1.43-4.59), multiparity (AOR = .44(.26-.74) and having a good awareness of puerperal sepsis prevention (AOR = 2.17(1.40-3.37) were factors identified to have a significant statistical association with good self-care practice towards prevention of puerperal sepsis.
Conclusion; this study revealed that less than half of postnatal mothers had good self-care practices for the prevention of puerperal sepsis. Healthcare providers and all stakeholders should focus on strategies to improve awareness of postnatal mothers about self-care practice in antenatal care clinics, during postnatal, at a community level with a special focus on postnatal mothers with no formal education and multiparous mothers.
Insula functional connectivity at EEG resting-state as a biomarker linked to pain processing and severity of clinical symptoms in fibromyalgia
Authors: Alves Rael Lopes , Zortea Maxciel , Serrano Paul Vicuña , Tomedi Rafaela Brugnera , Almeida Rodrigo Pereira , Torres Iraci Lucena Silva , Fregni Felipe , Caumo Wolnei 
Published: April 2023

Abstract
Brain areas and oscillations have been pointed out as markers of chronic pain. We used electroencephalography (EEG) to compare the linear and non-linear connectivity of regions of interest (ROIs) related to the pain matrix in people with fibromyalgia (FM) and healthy controls (HC). Sixty-four women (49 FM and 15 HC) volunteered to participate in a resting-state EEG session with eyes open (EO) and eyes closed (EC), as well as clinical, psychological, and serum brain-derived neurotrophic factor (BDNF). The connectivity of 10 ROIs was computed for 7 different EEG frequencies. In EC conditions, FM exhibits decreased non-linear connectivity in the beta-2 band between the right-insula and left mPFC (F=-4.09, p = .035). Considering the differences between EO and EC, FM present increased linear connectivity between the left insula and right thalamus in the beta-3 band (F = 3.46, p = .009) and increased non-linear connectivity between the right insula and left medial prefrontal cortex (mPFC) in the beta-2 band (F = 3.78, p = .025). These results mainly indicate the insula role in different circuits in FM and highlight the beta oscillations activity. Insular brain connectivity at rest could be an objective biomarker of how pain is processed, and it is related to the severity of clinical symptoms in fibromyalgia.
Seasonal Prevalence of Respiratory Pathogens Among Children in the United Arab Emirates: A Multicenter Cross-Sectional Study in the Pre-COVID19 Era.
Authors: Salim Sara , Celiloglu Handan , Tayyab Farah , Malik Zainab A. 
Published: April 2023

Abstract
Background
Viral respiratory infections in children pose a significant burden on healthcare facilities globally. In the United Arab Emirates (UAE) these account for 15% of all healthcare encounters among children. However, the seasonal prevalence and molecular epidemiology of respiratory viral infections in the UAE remains unknown. We sought to determine trends in seasonal viral prevalence in order to monitor disease activity and optimize timing of Respiratory Syncytial Virus (RSV) prophylaxis among high-risk infants in the UAE.
Methods
This cross-sectional multicenter study included children 0-18 years of age who presented to a large private healthcare group in Dubai, UAE, and had upper respiratory samples collected for multiplex polymerase chain reaction (mPCR) testing between January 1st and December 31st, 2019. Sociodemographic, clinical, and molecular data were examined for children who tested positive for any pathogen on the mPCR panel.
Results
A total of three thousand and ninety-eight infants and children had mPCR assays performed during the study period, of which 2427 (78.3%) were positive for any respiratory pathogen. The median age of our sample population was 39 months and 56.8% were male. Emergency room was the most common site (34.7%) of sample collection and the vast majority of children presented with fever (85.3%). Rhinovirus/enterovirus was the most prevalent viral infection (45%) throughout the year and peaked in September, followed by Influenza (20.2%), and RSV (17.1%). RSV season, defined as an infection prevalence of >10%, occurred from August to December with a peak in October. Adenovirus (15.6%) infections peaked in June and accounted for 43% of hospitalizations in our study (p<0.05). Viral co-infections with RSV and rhinovirus/enterovirus were most common and observed in 19.9 % of children.
Conclusion
Rhinovirus/enterovirus is the most prevalent viral pathogen throughout the calendar year among the pediatric population in the UAE. RSV season begins earlier than reported in other countries regionally, hence RSV prophylaxis should be initiated in August to optimize protection among high-risk infants.
Antioxidative barrier indicators of pre-school children in case of active dental caries
Authors: Yildirim Sinem , amenabar jose miguel , Bakkal Meltem 
Published: April 2023

Abstract
Background: Antioxidant system is a powerful defense system of the body works against damages caused by free radicals. The present study investigated the effect of active dental caries on oxidative stress by evaluating the antioxidative stress indicators in saliva and serum samples of children.
Methods: Thirty eight children aged between 35-72 months were participated in this study. Unstimulated whole saliva and serum samples were collected from the children before and after the performance of their dental treatments. Salivary; pH, flow rate and total protein concentrations were measured. Total antioxidant status (TAS) and Total oxidant status (TOS) levels of serum and saliva samples were determined. In addition, saliva and serum levels of Nitric oxide (NO), Catalase (CAT) and Glutathione peroxidase (GPx) were measured quantitatively.
Results: According to the quantitative measurements, TAS showed an increase in the post-treatment saliva/serum samples, whereas TOS had a decrease. In addition, NO and CAT levels of pre-treatment saliva/serum samples were higher than the levels found in post-treatment samples. It was also found that the concentrations of GPx increased statistically after treatment. The positive correlations of these parameters were found between whole saliva and serum samples, except the GPx levels.
Conclusions: Saliva is has a great potential in biomedical research, as well as serum and it constitutes a defence, against free radical-modified oxidative stress due to active dental caries. The oxidative/antioxidative balance appeared to shift toward the antioxidant status after the children became caries-free.
Benefit of an action camera in endoscopy education for medical students under COVID-19
Authors: Uchiyama Akira , Yamashina Shunhei , Sato Toshifumi , Sakuma Satoshi , Tomiki Yuichi , Isayama Hiroyuki , Nagahara Akihito , Ikejima Kenichi 
Published: April 2023

Abstract
Background
Endoscopy is an important form of clinical gastroenterology education because it gives students the opportunity to learn about diagnosis procedures and even treatment. During the COVID-19 pandemic, medical students were observed from outside the endoscopy room due to the risk of airborne infection. In this study, we investigated the efficacy of combining endoscopy education with doctor's-eye-view videos of the procedure obtained using live-action cameras (GoPro®).
Methods
From February to May 2021, endoscopists wore GoPro Hero8 cameras on their heads to display a doctor's-eye view video outside the room. The efficacy of the GoPro videos in combination with endoscopic monitoring was evaluated by 15 participating medical students. The participants rated the efficacy on a 5-point scale and commented on the positive and negative points.
Results
A total of 78.6% of participants evaluated the GoPro as good; 57.2% answered that it increased their understanding, with 71.4% stating that it increased their understanding of procedures in particular. A total of 85.7% of the students answered that their interest in endoscopy had increased, and 85.7% evaluated the benefit of the GoPro videos as good. In addition, 64.3% answered that the method was effective in preventing COVID-19 infection. Education using GoPro videos enabled students to feel as if they were conducting the endoscopy themselves and enabled them to concentrate on learning.
Conclusions
Practical endoscopic education using a GoPro is an effective educational tool that not only increases understanding of endoscopic practice but also stimulates students’ interest and awareness of their future as doctors.
Optimal and Near-optimal Frequency-hopping Sequences based on Gaussian Period
Authors: Wang Yan , Fu YanXi , Li Nian , Wang HuanYu 
Published: April 2023

Abstract
In frequency-hopping communication system, frequency-hopping sequences(FHSs) have a decisive influence on the whole frequency-hopping communication system. To construct FHS sets which meet the requirements of the theoretical bounds are important in researching frequency hopping communication system. In this paper, a new class of optimal FHSs and near-optimal FHSs based on trace functions are constructed. It is shown that the new FHSs are optimal according to the Lempel-Greenberger bound.
New Eco-Friendly Zinc-incorporated Urea Slow Release Fertilizer for Improving Zinc availability and Nitrogen Use Efficiency in Maize
Authors: Mirbolook Atena , Rasouli-Sadaghiani MirHasan , Keshavarz Payman , Alikhani Mina 
Published: April 2023

Abstract

Background and Aims

improving nitrogen (N) use efficiency (NUE) is necessary to reduce the entry of excess N into the environment and to retain N in the soil. Few studies have been done on dual-purpose slow release fertilizers using urea and zinc (Zn).

Methods

In this study, a new Zn-incorporated urea slow release fertilizer with diatomite (DE) and nano-diatomite (NDE) was synthesized. The treatments included the following: C: control, U: urea, Zn: zinc sulfate, UZn: urea-Zn complex, UZn-DE: urea-Zn-diatomite, UZn-NDE: urea-Zn-nano-diatomite. The slow-release urea-Zn fertilizers (SRUZns) were characterized using FESEM/EDS, FT-IR, CHN, DLS, and zeta potential techniques. First, the slow release behavior of SRUZns in soil was monitored. Then, a greenhouse study was carried out to check the agronomic effects of them on maize (Zea mays).

Results

Instrumental analyses indicated the binding of UZn complex into DE and NDE in the components. Usage of SRUZns lead to better retention of NH4+ relative to NO3−. UZn-NDE was twice as effective as UZn-DE in NH4+ retaining in the soil. Also, cumulative losses of Zn available in the soil was the lowest by UZn-NDE. Pot study revealed that UZn-fertilizers boosted the crop growth in comparison to the urea and zinc sulfate alone. N and Zn uptake and use efficiency improved significantly by SRUZn fertilizers in maize.

Conclusion

The results showed that the dual-purpose SRUZns with slow-release behavior could be reflected as well-organized N and Zn fertilizers in agricultural and horticultural with minimal environmental effluence.
Sphaerocoryne affinis fruit extract causes DNA damage leading to inhibited cell proliferation and activated apoptosis in cervical cancer cells
Authors: Le-Trung Nghia , Minh Tue Duong , Phuong Thao Dang Thi , Kamei Kaeko 
Published: April 2023

Abstract
Background
The roots, bark, leaves, branches, and flowers of Sphaerocoryne affinis (family Annonaceae) reportedly exert anti-cancer activity. Herein, we examined the anti-cancer potential of S. affinis fruit extracts using cervical cancer HeLa cells.
Methods
The solvent fractions of the S. affinis fruit extract were prepared and subjected to in vitro testing in cervical cancer (HeLa) and human embryonic kidney 293 (Hek-293) cells. The CCK 8 assay was used to determine the time- and dose-dependent cytotoxicity. DAPI staining was performed to determine the number of nuclei and assess cell morphology. The expression of γH2AX, cleaved-caspase-3, and cyclin E was determined using western blotting. Quantitative PCR determined the relative transcription levels of pro-apoptotic BAX, anti-apoptotic BCL2, and proliferating cell nuclear antigen (PCNA).
Results
The hexane fraction of S. affinis fruit extract exhibited cytotoxicity against HeLa and Hek293 cells, as determined by IC50 values (95% confidence interval [CI] 4.05–4.34 µg/mL and 10.61–37.52 µg/mL, respectively). Accordingly, S. affinis fruit extract exerted selective toxicity against cancer cells relative to normal cells, with a selectivity index between 2.45–9.26. In addition, the cells displayed abnormal morphology and nucleus shrinkage. The time-dependent cytotoxicity assay revealed that cell viability was unaltered during the initial 24 h of treatment. Cells treated with the hexane fraction of S. affinis fruit extract showed increased levels of the histone H2A variant, γH2AX, a marker for DNA damage. Furthermore, caspase-3 was activated in the extract-treated cell group. Expression of cyclin E, crucial for the G1 to S phase transition, was reduced in cells treated with the S. affinis fruit extract. Simultaneously, treatment with S. affinis fruit extract decreased the expression of PCNA mRNA, which is essential for replication.
Conclusion
Collectively, these findings indicate that S. affinis fruit extracts exert an anti-cancer effect by arresting the cell cycle of HeLa cells and inducing apoptosis owing to irreversible DNA damage.
Risk of fall in female Saudi students who engage in cognitive-motor dual tasks- A Cross Sectional Study
Authors: Alatawi Salem , Mahmoud Hayam 
Published: April 2023

Abstract
Background: Dual tasking (DT) requires individuals to carry out two actions simultaneously, comparable to how the brain can perform a cognitive function while the body is in motion, which eventually enhances human balance.
Objective: To examine and compare the impact of DT on the risk of falling (ROF) among Saudi female students enrolled in the literary and scientific faculties.
Method: A cross-sectional design was used. 120 female students consented to this study after 150 were invited. Specialization led to the formation of the scientific (SG, 86) and literary (LG, 34) groups. All participants, aged 18 to 25, had a normal BMI and normal cognitive and balance skills. Using the Biodex balancing system, ROF during balance alone (no DT) and with DT (motor and two types of cognitive tasks) were assessed. ROF was compared within and between groups using paired and unpaired T-tests, respectively. Mann-Whitney compared the two groups throughout the DT. The level of significant was considered at P=0.05.
Results: There was no significant difference in ROF in SG (P 0.05) between the performance with and without dual tasking, contrary, LG demonstrated a significant difference (P=0.05) for the same tests. In addition, the only time there was a significant difference between the two groups was when they performed DT.
Conclusion: SG students are better capable than LG students in maintaining balance and resisting the ROF during DT. This study's findings may pave the way for improved interventions to reduce fall risk and improve balance during neurorehabilitation.
Obstetric violence among HIV positive and negative women in Ghana: A cross sectional study in two regions
Authors: Appiah Seth Christopher Yaw , Yalley Abena Asefuaba , Ahlin Ekoutiame , Hoeffler Anke 
Published: April 2023

Abstract

Background: Although the problem of obstetric violence (OV) is receiving increasing attention among academics and policy makers, the prevalence and associated factors of OV are still poorly understood. The fear of OV prevents women from giving birth in health facilities, which is crucial for the effectiveness of HIV prevention programs, such as the Prevention of Mother to Child Transmission (PMTCT) program.
Objective: The aim of this paper is to determine the prevalence of OV, the comparative burden and associated predictors between HIV positive and negative women in Ghana.
Methods: The present study is a facility-based cross-sectional study enrolling 2,142 women, of which 310 were HIV positive and 1,832 HIV negative with a birth history of 0-24 months. The women were enrolled consecutively using a two stage sampling technique from eight hospitals with antiretroviral clinics across two regions in Ghana. The primary outcome variable was the experience of OV and its various forms. Descriptive data is presented in tables and reported in frequencies. The inferential analysis has been performed by estimating the Adjusted Odds Ratios (AOR) using multivariate logistic regression.
Results: Prevalence of OV was slightly lower among HIV positive women (61.0%) compared to HIV negative women (65.1%), though this was not statistically significant (χ2=1.99; p=0.158). The most common sub-category of OV experienced by all women was non-confidential care (35.2%). HIV positive women experienced more abandoned care (32.6%) with non-consented care being the least prevalent form of OV. Experience of discrimination was higher among HIV positive women (13.5%) than HIV negative women (10.8%). The multivariate regression analysis of the predictors of OV suggests that HIV positive women are not more likely to experience OV. Instead, we find evidence that HIV positive women are less likely to be subjected to physical violence (AOR=0.512; CI: 0.369-0.710), non-consented care (AOR=0.457; CI: 0.244-0.859) and non-dignified care (AOR= 0.688; CI: 0.513-0.923).
Conclusions: The study shows high rates of OV among all women. However, we found no evidence that HIV positive women were at higher risk to experience OV than HIV negative women. Evidence based interventions are required to address OV due to its threat to facility-based childbirth and the PMTCT cascade of care.
Evaluation of the Association of mir-143 and rs4705342 single nucleotide polymorphism with Oral Squamous cell carcinoma
Authors: Rezazadeh Hojat , Rezazadeh Fahimeh , ranjbar Zahra , Mokhtari Mohammad Javad , Fattahi Mohamad Javad , Semnani Mohammadsadegh Aghabababak , Aghasadeghi kiana 
Published: April 2023

Abstract
Introduction

Numerous studies have demonstrated that decreased expression of miR-143 is frequently observed in different cancer types, which can lead to an elevated probability of cell proliferation, migration, apoptosis, invasion, and epithelial to mesenchymal transition. Among, all head and neck cancers, oral squamous cell carcinoma (OSCC) is the most commonly occurring type. Thus, the aim of this research is to explore the possibility of scrutinizing the plausibility correlation between a functional polymorphism (i.e., rs4705342) located in the flanking region of miR-143 and the susceptibility of Iranian individuals to squamous cell carcinoma.

Methods

we recruited a total of 245 participants in this cross-sectional study, consisting of 95 patients diagnosed with OSCC and 150 healthy controls. The tetra-primer ARMS-PCR method was used to genotype the rs4705342 polymorphism. This method is a highly accurate and validated technique for detecting genetic variations. The genotyping results were further validated through DNA sequencing to ensure accuracy and minimize errors.

Results

Our analysis of the allele and genotype frequencies of the miR-143 rs4705342 polymorphism revealed significant differences between OSCC cases and controls. Using the chi-square test, we found that the P-value was less than 0.05, which indicates that the null hypothesis of no significant difference in gene expression between the two groups can be rejected. Therefore, our findings imply that the rs4705342 polymorphism might be linked with a higher susceptibility to OSCC in the Iranian population.

Conclusion

We have discovered evidence that supports the notion that the presence of the miR-143 rs4705342 polymorphism may be a contributing factor in the development of OSCC in the Iranian population. However, further studies, sample sizes and diverse populations are needed to better evaluate the significance of this genetic variation in OSCC pathogenesis. Overall, our findings emphasize the importance of identifying genetic factors that may influence cancer risk and the need for continued research to improve the prevention and treatment of this disease.