bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reconstructing Electric Double Layer with β‐diketone Additive for Highly Invertible Zn Anode
Authors: Wu Boyong , Yan Tong , Liu Sucheng , Su Yufeng , Xiang Cong , Li Minjian , Cui Zhiming , Du Li , Liang Zhenxing , Song Huiyu 
Published: January 2025

AbstractAqueous Zn ion batteries (AZIBs) have emerged as a promising option for energy storage on a large scale. However, the unsteady electric double layer (EDL) that causes the continuous H2O and SO42− induced side reactions and byproducts, results in unstable anode electrolyte interphase (AEI) and restricts the practical application of AZIBs. A novel EDL reconstruction strategy is proposed by a prior adsorption process of the organic molecules, achieving steady AEI and uniform Zn deposition. Experimental results and theoretical calculations illustrate that the zinc acetylacetonate (Zn(C5H7O2)2, Zn(acac)2) that conceives a pair of polar groups (─C═O) contributes to stability of AEI. As a result, the electrolyte with Zn(acac)2 additive (ZnSO4 + Zn(acac)2, ZAH) realizes Zn//Zn cells a highly invertible plating/stripping performance over 2400 h with an average Coulombic efficiency of 99.55%. Moreover, the Zn//NH4V4O10 pouch cells with ZAH electrolyte maintain an impressive capacity retention of 55.81% during 3000 cycles. These results spotlight the enormous potential of Zn(acac)2 additive, providing promising feasibility on highly reversible Zn anodes.
Engineered Bio‐Heterojunction for Effective Treatment of Colorectal Cancer Through Intratumoral Bacteria Scavenging and Autophagy Regulation
Authors: Chen Lin , Shen Yu , Shi Hongxing , Chen Yanbai , Yang Tinghan , Cao Wenchao , Jiang Tianxiang , Wei Mingtian , Deng Yi 
Published: January 2025

AbstractIntratumor bacteria, a critical component of the tumor microenvironment, can facilitate tumor growth and contribute to the development of resistance to chemotherapeutic agents. The agents not only induce protective autophagy in tumors, contributing to drug resistance, but also exert minimal effects on bacteria within the tumor, thereby potentially accelerating tumor recurrence. To address this tough issue, vermiculite/copper telluride bio‐heterojunctions (VIC bio‐HJs) have been developed to enhance tumor autophagy and eradicate bacteria within the tumor to obtain a victory in the fight against tumors. VIC bio‐HJs are able to generate substantial reactive oxygen species (ROS) via photodynamic/chemodynamic therapy, effectively eliminating bacteria within the tumor by disrupting bacterial integrity and impairing electron transport chains. Concurrently, increased production of ROS leads to decreased mitochondrial membrane potential and apoptosis in tumor cells. In vivo assays and sequencing analysis confirm that VIC bio‐HJs have excellent bacteria‐killing ability while being able to induce excessive autophagy in tumor cells, ultimately leading to more cell death. Such work proposes a strategy for designing bio‐heterojunctions capable of tumor eradication and bacteria removal, offering a promising approach to improve the efficacy of bacterial‐infiltrated tumor therapy.
Elevating the Concentration of Na Ions to 1 in P2 Type Layered Oxide Cathodes
Authors: Vasavan Hari Narayanan , Saxena Samriddhi , Srihari Velaga , Das Asish Kumar , Gami Pratiksha , Dagar Neha , Deswal Sonia , Kumar Pradeep , Poswal Himanshu Kumar , Kumar Sunil 
Published: January 2025

AbstractLayered oxide cathodes, particularly those with P2 and P3 type structures, have lower specific capacities limited by the Na‐ion content in their structure. In this study, the Na content is elevated to its uppermost limit with a cathode. The material is synthesized in a monophasic P3, monophasic P2 (with a minor O3 phase), and biphasic P3/P2 configuration. During electrochemical testing, the biphasic P3/P2 and the monophasic P2 type compounds exhibited excellent performance, with specific capacities reaching 102 and 87 mAh g−1, respectively, at 6C. A full cell fabricated using the monophasic P2 type cathode demonstrated a specific capacity of 123 mAh g−1 at 0.1C and retained 90% of its initial specific capacity after 200 cycles at 0.2C. The structural integrity of both the biphasic P3/P2 and the monophasic P2 type cathode materials is supported by the operando synchrotron X‐ray diffraction data, which showed no phase transformations and P2 phase showing only a 0.78% variation in unit cell volume. These findings highlight the transformative potential of achieving high Na‐ion concentrations in P2‐type cathode materials, paving the way for developing high‐performance sodium‐ion batteries.
Enhancing Peroxidase‐Like Activity and Photothermal Property of Copper Single‐Atom Nanozyme via A Cascade Competition Strategy
Authors: Wu Qiushuang , Zheng Guoan , Li Lihua , Wang Li 
Published: January 2025

AbstractSingle‐atom nanozymes (SANs) are promising enzyme‐active catalysts due to their maximum atomic utilization. However, it is still a challenge to precisely regulate the single‐atom structure, especially in multimetallic MOFs. Based on the Cu‐N4 structure of Zn4Cu1, a cascade competition strategy mediated by a buffer (polydopamine) is proposed for the first time, which induces a one‐step nonthermal reaction to precisely remove the inactive Zn site and adjust the Cu coordination environment. Experimental results and theoretical calculations show that the Cu single‐atom nanozyme with Cu‐N2O2 structure (Cu‐N/O) breaks the strong steric restriction, and the exposed Cu active site can better adsorb H2O2, making it have peroxidase‐like activity. Compared with traditional bimetallic (Cu4Zn1) and monometallic (Cu‐MoF) nanozymes, it has stronger peroxidase‐like catalytic activity and photothermal properties, as well as good photocatalytic activity and extremely strong stability. It is successfully applied to Lateral flow immunoassay to achieve three‐mode ultrasensitive detection of Escherichia coli O157:H7, and the test strips after detection are subjected to broad‐spectrum sterilization treatment.
Surface Modification of 3D Biomimetic Shark Denticle Structures for Drag Reduction
Authors: Yang Kang , Yu Xinping , Cui Xianxian , Chen Dengke , Shen Tao , Liu Zhuoxing , Zhang Bowen , Chen Huawei , Fang Ruochen , Dong Zhichao , Jiang Lei 
Published: January 2025

AbstractShark skin features superhydrophilic and riblet‐textured denticles that provide drag reduction, antifouling, and mechanical protection. The artificial riblet structures exhibit drag reduction capabilities in turbulent flow. However, the effects of the surface wettability of shark denticles and the cavity region underneath the denticle crown on drag reduction remain insufficiently explored. Here, 3D printing is utilized to fabricate realistic staggered and overlapped denticle arrays, modified to achieve superhydrophilic, superhydrophobic, and hybrid configurations, including external riblets hydrophilic/internal cavities hydrophobic (ELIB), and vice versa (EBIL). Denticles of varying heights are also fabricated. The results indicate that superhydrophobic, ELIB, and EBIL denticles outperform superhydrophilic ones in reducing drag, achieving a peak drag reduction rate of ≈20%. Notably, shorter denticles further improve drag reduction. Reduced vortex formation within the underneath cavity correlates with improved drag reduction. These vortices can function similarly to rolling bearings while facilitating momentum exchange and increasing skin friction drag. Superhydrophobic or partially superhydrophobic denticles (ELIBD/EBILD) mitigate this effect. This study suggests that sharks may secrete mucus on specific sections of their denticles to further reduce vorticity and drag, offering novel insights into the biomimetic design of shark denticles for optimized drag reduction.
Tuning the Electroluminescence of Binuclear Copper(I) Emitters Into the NIR‐I Region
Authors: Jouaiti Abdelaziz , Ballerini Lavinia , Zhang Wei‐Min , Polo Federico , Gourlaouen Christophe , Su Hai‐Ching , Mauro Matteo 
Published: January 2025

AbstractOptoelectronic devices that emit into the near infrared (NIR) region are appealing technologies with applications in optical communication and as disposable, lightweight and cheaper photodynamic biomedical devices. The development of efficient devices is currently hampered by the lack of suitable NIR‐emissive materials. Achieving this goal is even more challenging when the use of non‐toxic, earth‐abundant metal complexes as electroactive materials is targeted. Herein, an enlarge family of binuclear Cu(I) emitters (D1–D4) bearing the bridging thiazolo[5,4‐d]thiazole scaffold is described along with their mononuclear counterparts (M3–M4), which are synthetized and characterized comprehensively by a combination of chemical, spectroscopical, electrochemical and computational techniques. By means of an efficient dinuclearisation strategy in combination with the selective tuning of the π‐accepting feature of the lateral N‐heterocyclic rings enabled modulation of photo‐ and electro‐luminescence spectra into the NIR‐I region. Light‐emitting electrochemical cells (LECs) fabricated by employing the binuclear copper complexes displayed electroluminescence into the deep‐red to NIR‐I region. Remarkably, derivative D2 shows the combination of λEL,max up to 782 with a spectral profile squarely falling into the NIR region, excellent carrier balance and good EL performances among all types of emissive materials used for NIR LECs.
Site Substitution Triggered Luminescence Characteristics Modulation in Eu3+‐Activated Sr4La6(SiO4)6Cl2 Phosphors for Boosting Viral Resistance and Plant Growth
Authors: Wang Yonghao , Shen Minjie , Zheng Hongying , Lu Yuwen , Du Peng 
Published: January 2025

AbstractA series of Eu3+‐activated Sr4La6(SiO4)6Cl2 (SLSCl) phosphors are prepared to fulfill the requirements of plant growth and immunity. Upon 394 nm excitation, the resulting phosphors can emit intense red emission from Eu3+, of which their intensities are sensitive to dopant content and site occupation. When Eu3+ occupies La3+ and Sr2+ sites, its optimal doping contents in SLSCl host lattices is 40 and 50 mol%, respectively. Moreover, the quantum efficiency and thermal stability of designed phosphors are also greatly dependent on the site taken by Eu3+ in SLSCl host lattices. Via utilizing the designed phosphors as red‐emitting converters, two different light‐emitting diodes (LEDs) are fabricated, whose emission bands overlap with the absorption bands of plant pigments, enabling their feasibilities in plant growth. Furthermore, the plant growth experiments indicate that the photosynthesis can be significantly improved via employing the packaged LEDs as supplementary lights. Additionally, the packaged red‐emitting LEDs can enhance the resistance of the N. benthamiana plants against viral infection. The findings do not only propose a facile route to manipulate the luminescence properties of Eu3+‐activated phosphors, but also confirm that the utilization of red light as supplementary light is an efficient to promote plant growth and viral resistance.
Chemical Substitution‐Driven Design of a High‐Performance Noncentrosymmetric Bismuth Molybdenum Selenite
Authors: Ngo Hieu Minh , Kuk Yunseung , Lee Jihyun , Lu Jiachen , Bai Zhiyong , Hu Chun‐Li , Ok Kang Min 
Published: January 2025

AbstractThe hydrothermal synthesis and characterization of a novel bismuth molybdenum selenite material, Bi2F2(MoO3)2(SeO3)2·H2O, designed using a chemical substitution‐based approach, is reported. This material represents the first example of its kind in the Bi–Mo–Se system, providing new insights into noncentrosymmetric (NCS) crystal engineering. The compound exhibits outstanding nonlinear optical (NLO) properties, including a second‐harmonic generation (SHG) efficiency 1.2 times that of KTiOPO₄ and a birefringence of 0.118 at 546.1 nm. Additionally, it demonstrates a wide transparency range (0.36–10 µm), making it a promising candidate for advanced NLO applications. Structural and computational analyses show that the remarkable SHG response is driven by the highly distorted MoO₆ octahedra, strong interatomic interactions within 1D chains, and the highly polarizable Bi3⁺ and SeO₃ groups. Furthermore, the compound is thermally stable after dehydration and exhibits a strong affinity for occupying its void space within the 5‐membered ring (5‐MR). These findings open new avenues for the design of NCS materials with enhanced optical functionalities, offering significant potential in the development of advanced solid‐state materials.
An Analysis of Elusive Relationships in Floating Zone Growth Using Data Mining Techniques
Authors: Vieira Lucas , Menzel Robert , Holena Martin , Dropka Natasha 
Published: January 2025

AbstractHigh‐purity silicon single crystals, essential in the renewable energy value chain, can be grown using the Floating Zone (FZ) method. Increasing the yield of the FZ process while maintaining its stability is a complex but sought‐after goal. This study examines intricate relationships in FZ growth, focusing on how representative crystal quality and process stability measures are influenced by various process parameters simultaneously. Data mining techniques are applied to synthetic data from numerical simulations. Regression Trees identified model parameters and their ranges responsible for complex behavior of the quantities of interest, some of which are undetected by bivariate correlation coefficients. Quantities at the center of the crystal are highly affected by the crystal radius and pulling rate, while quantities near the surface of the crystal are more sensitive to the reflector and inductor parameters due to their proximity. The results illustrate how data mining techniques can support informed parameter engineering of the FZ process toward desirable goals.
Inspecting the Role of Dimensional Anisotropy and Oxidized Environment on the Complex Dielectric Responses of CdSe/ZnS Ellipsoidal Core/Shell Quantum Dots with Embedded Impurities
Authors: Naifar A. , Hasanirokh K. 
Published: January 2025

AbstractThis research investigates the interplay between self‐polarization, structural anisotropy and impurity effects on the complex dielectric function (CDF) of CdSe/ZnS ellipsoidal core–shell quantum dots (ECSQDs) surrounded by HfO2 and SiO2 oxides with the aim of optimizing their performance in next‐generation optoelectronic devices. Analytical formulas of linear and third order nonlinear optical of susceptibility χ(3) as well as the CDF are derived by compact‐density matrix formalism applied to a two‐state system. Numerical results indicated that electron energy states exhibited a complex dependence on both core and shell ellipticity (δ1 and δ2) along with witnessed red and blue shifts due to anisotropic quantum confinement along the major and minor axes. The oscillator strengths of quantum transitions non‐monotonously depend on the structural anisotropy of the layers due to the different location of carriers. More importantly, computations showed that resonant peaks of real and imaginary parts of CDF could be precisely modulated through the dielectric medium, shape‐induced effects and size parameters. The Eccentricity of the core seems to dominate over that of the shell affecting the amplitude of computed nonlinear properties. Our model can be engineered to optimize electron transport by enhancing energy confinement and protecting quantum information from destructive interference mechanisms.
Humanized Candida and NanoBiT Assays Expedite Discovery of Bdf1 Bromodomain Inhibitors With Antifungal Potential
Authors: Wei Kaiyao , Arlotto Marie , Overhulse Justin M. , Dinh Tuan‐Anh , Zhou Yingsheng , Dupper Nathan J. , Yang Jiayi , Kashemirov Boris A. , Dawi Hasan , Garnaud Cécile , Bourgine Gaëlle , Mietton Flore , Champleboux Morgane , Larabi Amédé , Hayat Yordan , Indorato Rose‐Laure , Noirclerc‐Savoye Marjolaine , Skoufias Dimitrios , Cornet Muriel , Rabut Gwenaël , McKenna Charles E. , Petosa Carlo , Govin Jérôme 
Published: January 2025

AbstractThe fungal Bromodomain and Extra‐Terminal (BET) protein Bdf1 is a potential antifungal target against invasive fungal infections. However, the need to selectively inhibit both Bdf1 bromodomains (BDs) over human orthologs and the lack of molecular tools to assess on‐target antifungal efficacy hamper efforts to develop Bdf1 BD inhibitors as antifungal therapeutics. This study reports a phenyltriazine compound that inhibits both Bdf1 BDs from the human fungal pathogen Candida glabrata with selectivity over the orthologous BDs from the human BET protein Brd4. On‐target antifungal activity is established by devising two yeast‐based inhibition assays: a growth assay using humanized Candida strains in which the Bdf1 BDs are replaced by their Brd4 counterparts, and a NanoBiT assay that evaluates the BD‐mediated association of Bdf1 with chromatin. These assays additionally enable the discovery that BET inhibitor I‐BET726 targets both Bdf1 BDs, inhibits the growth of a broad spectrum of Candida species, including antifungal‐resistant clinical isolates, and displays efficacy in an invertebrate animal model of infection. These collective findings highlight the promising potential of Bdf1 BD inhibitors as an innovative class of antifungal therapeutics and the pivotal role of yeast‐based assay development toward achieving this end.
Left Insula and Right Middle Temporal Gyrus Dominate Cortical Network Discriminating Arousal‐dependent Emotions
Authors: Pan Na Clara , Gao Runshi , Ma Kai , Qiao Liang , Ni Duanyu , Yu Tao , Wang Yuping 
Published: January 2025

AbstractEmotion processing is an integral part of everyone's life. The basic neural circuits involved in emotion perception are becoming clear, though the emotion's cognitive processing remains under investigation. Utilizing the stereo‐electroencephalograph with high temporal‐spatial resolution, this study aims to decipher the neural pathway responsible for discriminating low‐arousal and high‐arousal emotions. This study involves 19 patients with pharmacologically resistant epilepsy who participate in a delayed match/mismatch sample task designed to separately assess their ability to discriminate between low‐arousal and high‐arousal emotions. Three groups of 11 brain subregions, with dominant lateralization, compose a network, which is identified as responsible for discriminating arousal‐dependent emotions. The connection of these subregions, leading by the left insula and right middle temporal gyrus, defines the pathways for discriminating emotions with different arousals. Further, the separated network patterns related to emotional discrimination are face‐independent. Overall, the left insula and the right middle temporal gyrus emerge as core components in the network, which plays key roles in the dynamic course for discriminating low‐ and high‐arousal emotions in the human brain.
A New Nanocomposite Electrode Developed from Environmental Atmosphere Triggered Reconstruction for Efficient Reversible Protonic Ceramic Cells
Authors: Wu Jie , Xie Zhenghui , Liang Mingzhuang , Chen Wanqing , Liu Dongliang , Yi Yongning , Luo Zhixin , Ran Ran , Zhou Wei , Wang Wei , Shao Zongping 
Published: January 2025

AbstractReversible protonic ceramic cells (r‐PCCs) are highly attractive energy storage and conversion technology, while the insufficient activity of state‐of‐the‐art air electrodes at reduced temperatures strongly limits their practical applications. Herein, this work reports a reduction/re‐oxidation strategy to design a new highly efficient, and durable nanocomposite air electrode for boosting the performance of r‐PCCs operated at intermediate temperatures. Specifically, single‐phase Ba(Co0.4Fe0.4Zr0.1Y0.1)0.9Ni0.1O3‐δ perovskite is selected as the precursor, its treatment in hydrogen atmosphere at 450 °C and then re‐oxidation in air leads to the formation of a nanocomposite, consisted of a perovskite‐based main phase and BaCoO3‐δ and NiO secondary‐phase nanoparticles, where the BaCoO3‐δ phase facilitates oxygen surface exchange while NiO nanoparticles promote surface oxygen/steam adsorption. The corresponding r‐PCC exhibits superior performance at 550 °C in a symmetrical cell (0.162 Ω cm2), a single fuel cell (0.690 W cm−2) and an electrolysis cell (−1.066 A cm−2 at 1.3 V). Such nanocomposite is thermodynamically stable at intermediate temperatures and offers better thermomechanical compatibility with protonic electrolyte because of the reduced thermal expansion coefficient. As a result, superior durability in both fuel and electrolysis cell modes is demonstrated. This study paves a new way for designing outstanding air electrodes for r‐PCCs with great application potential.
H2S‐Activated Near‐Infrared Emission Chemiluminescent Probes for Precise Diagnosis of Inflammations and Tumors
Authors: Liang Mengke , Zhang Ling'e , Yu Bo , Geng Zirui , Ge Huazhen , Sun Ying , Liu Luyu , Jiang Xiqun , Wu Wei 
Published: January 2025

ABSTRACTCompared to fluorescence imaging, chemiluminescence imaging does not need external excitation light, and hence presents high imaging depth and signal‐to‐noise ratio without autofluorescence and phototoxicity, making it a promising tool for biological detection and analysis. However, the target‐specific activatable near‐infrared emission chemiluminescent probes still need to be developed for the precise diagnosis of diseases. In this paper, we synthesized four direct near‐infrared emission Schaap's chemiluminophores (AINCL, AIFCL, ABTCL, and APYCL) by incorporating different electronic acceptors, respectively, and studied the effect of the acceptors on the optical properties of the chemiluminophores. To achieve the specific detection of hydrogen sulfide (H2S)‐related diseases, we used H2S‐cleavable 2,4‐dinitrophenylsulfonate to cage the phenol groups in the chemiluminophores. It was demonstrated that the endogenous H2S in inflammations and tumors could activate effectively the chemiluminescence with high specificity, which provided the precise location of nidus in chemiluminescence imaging and allowed us to perform surgical resection.
Therapeutic Errors Associated With Antithrombotic Medications Reported to United States Poison Centers
Authors: Cravo Emma N. , Hays Hannah L. , Badeti Jaahnavi , Spiller Henry A. , Rine Natalie I. , Zhu Motao , Smith Gary A. 
Published: January 2025

ABSTRACTThe objective of this study was to investigate the characteristics and trends of therapeutic errors in non‐healthcare facility settings associated with antithrombotic medications reported to United States Poison Centers by analyzing data from the National Poison Data System from 2000 to 2021. There were 57 288 reported therapeutic error‐related exposures involving antithrombotic medications as the primary substance. The rate of therapeutic errors increased by 590.9% during this 22‐year period. Although most (90.1%) therapeutic errors were clinically inconsequential and did not receive treatment at a healthcare facility, 2.3% were medically admitted, and 2.1% experienced a serious medical outcome, including 16 fatalities. Three‐fourths (74.9%) of therapeutic errors were among > 59‐year‐olds, and females represented 58.0% of exposures. Warfarin was the most commonly involved antithrombotic medication (37.5%), followed by direct oral anticoagulants (DOACs, 28.7%) and clopidogrel (23.3%). Therapeutic errors involving warfarin were more likely to be associated with a medical admission (odds ratio [OR] = 2.23; 95% confidence interval [CI]: 1.99–2.49) or a serious medical outcome (OR = 2.99; 95% CI: 2.65–3.37), and DOACs were less likely to be associated with a medical admission (OR = 0.53, 95% CI: 0.46–0.61) or a serious medical outcome (OR = 0.45; 95% CI: 0.38–0.53) than therapeutic errors involving other antithrombotic medications. The rate of therapeutic errors involving warfarin significantly increased by 187.0% during 2000–2011, followed by a 57.6% significant decrease during 2011–2021. The rate of therapeutic errors involving DOACs increased significantly by 1118.2% during 2011–2021. The scenario “inadvertently took/given medication twice” accounted for 56.3% of all therapeutic errors. Increased risk reduction efforts are needed to prevent antithrombotic‐related therapeutic errors.