bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Role of Ayushman Bharat Health Account (ABHA) in Telehealth: A New Frontier of Smart Healthcare Delivery in India
Authors: Paliwal Sushila , Parveen Suraiya , Singh Ompal , Alam M. Afshar , Ahmed Jawed 
Published: May 2023

Abstract
This paper draws attention to the Ayushman Bharat Health Account (ABHA), which constitutes a pivotal element of the Ayushman Bharat Digital Mission (ABDM) implemented in India. The ABHA database functions as a centralised repository of health-related information, offering a platform for IEC initiatives aimed at increasing awareness, encouraging healthy behaviours, and disseminating public health messaging. The integration of Information, Education, and Communication (IEC) and Artificial Intelligence (AI) technologies has the potential to augment patient education and engagement, streamline disease prevention initiatives, and enhance health literacy. Centralized health data can help in promoting telehealth by providing health care providers with access to patient medical records, enabling them to provide remote consultations and treatments. Exploring the function of Ayushman Bharat Health Account (ABHA) in telehealth for sustainable development necessitates an interdisciplinary view of healthcare delivery in India. Telehealth, which is the use of technology to provide remote healthcare services, can increase the reach and efficacy of ABHA. The adoption and success of ABHA and telehealth in India are influenced by numerous social, economic, technological, and policy-related factors, which can be identified through an interdisciplinary research approach. Such research can inform the development of a sustainable healthcare system that capitalizes on the strengths of ABHA and telehealth to enhance the population's health and well-being in India. This paper proposes the implementation of ABHA, IEC, AI, and telehealth in India, which have the potential to transform healthcare delivery by augmenting patient care, strengthening disease prevention efforts, and encouraging healthy lifestyles. This approach can potentially save lives and reduce healthcare costs in the long run. However, the implementation of such a system may raise concerns over privacy and data security, especially in a country with a large population and limited resources for enforcing regulations and protecting sensitive information.
Nutritional status of children with neurodevelopmental disorders: A cross-sectional study at the tertiary level hospital in northern Bangladesh
Authors: Khatun Rabeya , Siddique Md. Kaoser Bin , Khatun Mst. Reshma , Benzir Maskura , Islam Md. Rafiqul , Ahmed Sohel 
Published: May 2023

Abstract

Background
Neurodevelopmental disorders (NDD) are a significant global public health issue. It was often thought that such children's malnutrition was a sign of illness, but it is now obvious how crucial their nutrition is.
Objectives
This study's objective was to assess the sociodemographic profile and nutritional status of children with neurodevelopmental disorders.
Methods
157 NDD-affected children who attended the pediatric clinics of the TMSS Medical College and Rafatullah Community Hospital in Bogura between December 2020 and April 2022 took part in a cross-sectional study using a purposive sample strategy. Using metrics such z-scores for weight-for-age (WAZ), height-for-age (HAZ), and body mass index-for-age percentile, the nutritional condition of children with neurodevelopmental disorders was evaluated (BAZ). Using the SPSS version 25, descriptive statistics (number and percentage) and analytical statistics (chi-square or Fisher's exact test, if appropriate) were both employed.
Results
A total of 157 children, whose ages ranged from 6 to 144 months, were taken part in this study. Around 58.6% of children with NDDs had malnutrition, 47.8% had under-nutrition, and 10.8% had over-nutrition. There was a significant correlation between malnutrition and parental education level, fathers' employment, residency, and monthly family income (P 0.05).
Conclusions
More over half of the NDD youngsters were found to be malnourished, according to the research, which offers us a peek of their nutritional health. The socioeconomic position of the parents has a significant impact on the nutritional status of these kids.
The frequency of colon lesions in the first-degree relatives of patients with adenomatous polyp or premalignant/ malignant colon lesions referring to the PERSIAN Guilan Elderly Cohort Study (PGECS)
Authors: Matin Somaieh , Joukar Farahnaz , Maroufizadeh Saman , Asgharnezhad Mehrnaz , Karimian Paridokht , Mansour-Ghanaei Fariborz 
Published: May 2023

Abstract
Background
Family history of colon cancer or adenomatous polyp is associated with an increased risk of colon cancer. The aim of this study was to investigate the frequency of colonic lesions in the first-degree relatives of patients with adenomatous polyp or premalignant/ malignant colon lesions referring to the geriatric cohort of Guilan.
Methods
In this cross-sectional study, 162 subjects who were the first-degree relatives of 52 patients with adenomatous polyp were investigated and underwent total colonoscopy based on the guidelines proposed for screening colorectal cancer. Moreover, the subjects’ demographic information, colonoscopy results, and pathological findings were recorded using a checklist Logistic regression with backward elimination (p-value for removal > 0.1) was used to identify factors associated with presence of colon polyps. Odds ratio (OR) and 95% confidence interval (CI) were calculated.
Results
In total, 86 colon polyps (52 neoplastic and 34 non-neoplastic polyps) were observed in 56 (34.6%) individuals. Being older, higher BMI, cigarette smoking, and diabetes were significantly associated with a greater risk of having colon polyps. In contrast, higher consumption of vegetables as well as fruits were significantly associated with a less risk of having colon polyps.
Conclusions
Considering the high prevalence of neoplastic colon polyps among the first-degree relatives of the patients with adenomatous polyp, early screening is recommended for the people with family history of this disease in the same way that people with family history of colorectal cancer (CRC) are screened.
Invertebrate diversity in peri-urban community gardens and possible mechanisms of community assemblage
Authors: Ploessl Savanna , Willden Samantha , Ingwell Laura 
Published: May 2023

Abstract
Urban farming is becoming increasingly popular to address food insecurity in the U.S., especially in response to the COVID-19 pandemic. However, a major challenge on urban farms is pest identification and management. In addition, urban farms are diverse and occur in nonmetro and metropolitan areas alike, therefore tailored recommendations for pest management are needed to reflect this diversity. The primary objective of this study was to describe invertebrate community composition at 10 urban community gardens across two counties in Indiana. We also aimed to identify possible mechanisms that determine community assemblages, such as garden size, surrounding land use, ground cover management, and crop diversity. Using pitfall traps, sticky cards, and visual assessments, we determined that herbivores represent the dominant feeding guild at community gardens, and herbivore counts were highest on zucchini and tomato. However, sentinel prey releases determined that predators and parasitoids are important regulators of pest populations. Overall, the assemblage of feeding guilds was similar across sites, suggesting a common metapopulation present in the surrounding landscape. On-farm practices that had the greatest influence on insect diversity were crop diversity, the presence of floral resources, and ground cover management. Insect diversity was positively correlated with crop diversity, and pollination activity was associated with flowering crops, namely dill. Parasitoid counts on sticky cards were often associated with sites that had additional ground cover. This study provides useful insights on the dominant invertebrate groups present at urban community gardens in Indiana and accessible on-farm practices to improve farm biodiversity.
Disseminating Evidence in Medical Education: Journal Club as a Virtual Community of Practice
Authors: Gold Jonathan , Forbes Karen L. , Pahwa Amit 
Published: May 2023

Abstract
Background
This study explores the impacts of the Council on Medical Student Education in Pediatrics (COMSEP) Journal Club, a unique means of providing monthly professional development for a large community of pediatric undergraduate medical educators. In particular, we sought to establish member engagement with the Journal Club, identify factors impacting member contributions to the Journal Club, and determine perceived benefits of and barriers to participation as a Journal Club reviewer.
Methods
Using an established Annual Survey as a study instrument, six survey questions were distributed to members of COMSEP. Items were pilot tested prior to inclusion. Quantitative data were analyzed using descriptive statistics.
Results
Of 125 respondents who completed the survey, 38% reported reading the Journal Club most months or always. Level of engagement varied. Reasons for reading included a topic of interest, keeping up to date on medical education literature, gaining practical tips for teaching and implementing new curricula. Motivators for writing a review included keeping up to date, contributing to a professional organization, and developing skill in analyzing medical education literature, with a minority citing reasons of enhancing their educational portfolio or academic promotion. The most commonly cited barriers were lack of time and lack of confidence or training in ability to analyze medical education literature.
Conclusion
As a strategy to disseminate the latest evidence in medical education to its membership, the COMSEP Journal Club is effective. Its format is ideally suited for busy educators and may help in members’ professional development and in the development of a community of practice.
Linking assessment to real life practice - comparing work based assessments and objective structured clinical examinations using mystery shopping
Authors: Lim Angelina , Krishnan Sunanthiny , Singh Harjit , Furtletti Simon , Sarkar Mahbub , Stewart Derek , Malone Daniel 
Published: May 2023

Abstract
Objective Structured Clinical Examinations (OSCEs) and Work Based Assessments (WBAs) are the mainstays of assessing clinical competency in health professions’ education. Underpinned by the extrapolation inference in Kane Validity’s Framework, the purpose of this study is to determine whether OSCEs translate to real life performance by comparing students’ OSCE performance to their performance in real-life (as a WBA) using the same clinical scenario, and to understand factors that affect students’ performance. A sequential explanatory mixed methods approach where a grade comparison between students’ performance in their OSCE and WBA (conducted as a mystery shopper visit at the workplace) was performed, students were then followed up with semi-structured interviews to discuss the students’ experiences in both settings. Students were third year pharmacy undergraduates in 2022. Overall, 92 mystery shopper (WBA) visits with students were conducted and 36 follow-up interviews were completed. The median WBA score was 39.2% lower compared to the OSCE score (p < 0.001). Interviews revealed students knew they did not perform as well in the WBA compared to their OSCE, but reflected that they still need OSCEs to prepare them to manage a real-life patient. Many students related their performance to how they perceived their role in OSCEs versus WBAs, and that OSCEs allowed them more autonomy to manage the patient as oppose to an unfamiliar workplace. As suggested by the activity theory, the performance of the student can be driven by their motivation which differed in the two contexts.
Computational analysis of Epstein-Barr virus microRNA regulation on long non-coding RNAs in nasopharyngeal cancer
Authors: Jawai Daphne Olivia , Sim Edmund Ui Hang 
Published: May 2023

Abstract
To date, the regulatory framework mediated by Epstein-Barr virus (EBV) BART microRNAs (miRNAs) via their interaction with long non-coding RNAs (lncRNAs) in the context of nasopharyngeal cancer (NPC) pathogenesis remains partially understood. To derive a more complete insight into this phenomenon, we embarked on a computational study to identify BART miRNAs, lncRNAs, and all associate factors relevant to NPC tumourigenesis, and to characterise their interactions. In silico integration of multi-level RNA expression and construction of regulatory networks were performed. We found six EBV BART miRNAs (ebv- miR-BART21-3p, ebv-miR-BART19-3p, ebv-miR-BART15, ebv-miR-BART2-5p, ebv-miR-BART20-3p and ebv-miR-BART11-5p) that can interact with four messenger RNAs (mRNAs) (EYA4, EYA1, EBF1 and MACROD2) associated with NPC pathogenesis. These mRNAs can interact with six non-EBV miRNAs (hsa-miR-1246, hsa-miR-93-5p, hsa-miR-16-5p, hsa-miR-135b-5p, hsa-miR-211-5p and hsa-miR-1305), which in turn, could interact with three lncRNAs (CASC2, TPTE2P1 and ARHGEF26- AS1). These findings could shed light on the roles of dysregulated competing endogenous RNAs (ceRNA) network in NPC oncogenesis. In addition, we have also predicted the oncogenic and tumour suppressive functions of BART miRNAs and lncRNAs, and more precisely the involvement of BART miRNAs in DNA repair regulation and apoptosis.
Association of mitochondrial DNA copy number with chronic kidney disease in older adults
Authors: Liu Yang , Pan Ying , Tian Zijian , Wang Jing , Chen Fei , Geng Zhaoxu , Li Qian , Liu Ziqing , Zhou Xiaozhou , Zhou Kaixin 
Published: May 2023

Abstract
Background
Mitochondrial dysfunction in kidney cells has been implicated in the pathogenesis of chronic kidney disease (CKD). Estimation of mitochondrial DNA copy number (mtDNA-CN) is considered a convenient method for representing mitochondrial function in large samples. However, no study has investigated the association between mtDNA-CN and CKD in older adults with the highest prevalence. The objective is to examine cross-sectional and prospective associations between mtDNA-CN values and CKD risk in older adults to determine whether mtDNA-CN represents a novel potential biomarker for the recognition of CKD risk.
Patients and Methods:
In a Chinese community-based cohort of over 65-year-olds, we included 14467 participants (52.6% females). CKD was defined by eGFR < 60 mL/min/1.73 m2 or ICD-10 codes (patients = 3831 (26.5%)). Participants had peripheral blood levels of mtDNA-CN calculated from probe intensities of the Axiom CAS Array.
Results
The risk of CKD prevalence decreased with mtDNA-CN per 1-SD increment, independent of established risk factors for older CKD (odds ratio [OR] per SD 0.90, 95% confidence interval [CI] 0.86, 0.93, P < 0.001), and has comparable strength of association with these established risk factors. Furthermore, the progression of kidney function was stratified according to the worsening of eGFR categories. The risk of kidney function progression to a more severe stage gradually decreased as the mtDNA-CN increased (P trend < 0.001). Non-CKD participants in the highest quartile of mtDNA-CN had a lower risk of developing CKD compared to the lowest quartile within 2 years of follow-up, reducing the risk of CKD by 34% (95% CI 0.42, 0.97; P = 0.037).
Conclusions
Based on the analysis of the largest sample to date investigating the association between mtDNA-CN and CKD in older adults, higher levels of mtDNA-CN were found to be associated with a lower risk of CKD, suggesting that a reduced level of mtDNA-CN is a potential risk factor for CKD.
FACEmemory®, an innovative online platform for episodic memory pre-screening: findings from the first 3,000 participants
Authors: Alegret Montserrat , García-Gutiérrez Fernando , Muñoz Nathalia , Espinosa Ana , Ortega Gemma , Lleonart Núria , Rodríguez Isabel , Rosende-Roca Maitee , Pytel Vanesa , Cantero-Fortiz Yahveth , Rentz Dorene M. , Marquié Marta , Valero Sergi , Ruiz Agustin , Butler Christopher , Boada Mercè 
Published: May 2023

Abstract
Background: The FACEmemory® online platform comprises a novel, self-administered memory test with embedded voice recognition technology and a questionnaire with relevant sociodemographic and medical/family history data. This is the first study about a completely self-administered memory test with voice recognition, pre-tested in a memory clinic, offered freely worldwide on a website platform. The aims of this study are to investigate the demographic and clinical variables associated with FACEmemory total score, and to identify differentiable patterns of memory performance among the first 3,000 individuals who completed the FACEmemory.
Methods: A marketing campaign was carried out to make FACEmemory accessible worldwide to individuals whose native language was Spanish or Catalan. Data from the first 3,000 subjects over 18 years old who completed the FACEmemory were analysed. Descriptive analyses were applied to demographic, FACEmemory scores, and medical/family history variables reported in a questionnaire; t-test and chi-square analyses were used to compare participants with preserved (>31 points) versus impaired performance (<32) on total FACEmemory; and multiple linear regression was used to identify variables that modulate FACEmemory performance. Finally, Machine Learning techniques were applied to identify differentiable patterns of memory performance.
Results: The study sample had a mean age of 50.57 years and 13.65 years of schooling. 64.1% were women and most (82.1%) participants reported memory complaints that worried them. The group with impaired FACEmemory performance (20.4%) was older, had fewer years of formal education and a higher prevalence of hypertension, diabetes mellitus, dyslipidemia, and family history of a neurodegenerative disease compared with the group with preserved FACEmemory performance. Multiple regression analysis showed that age, schooling, sex, country and completion of the questionnaire were statistically associated with FACEmemory total score. Finally, Machine Learning techniques identified 4 patterns of FACEmemory performance: normal, dysexecutive, storage and completely impaired.
Conclusions: FACEmemory is a promising tool for the pre-screening of people with subjective memory complaints in the community in order to identify those with objective memory deficits and raise awareness about cognitive decline. The FACEmemory website platform is an opportunity to facilitate a free, online and self-administered episodic memory assessment to Spanish or Catalan speaking individuals worldwide, and potentially extensible to other languages.
Modelling Quinoa (Chenopodium quinoa Willd.) Seed Yield and Evapotranspiration under Water, Salt and Combined Water-Salt Stress
Authors: Hoşgören Çiğdem , Semiz Gülüzar Duygu , Ünlü Mustafa , Suarez Donald L. 
Published: May 2023

AbstractWe studied the responses of quinoa (Chenopodium quinoaWilld.) to single and combined effects of four different irrigation water salinity (electrical conductivity) levels (S1: 0.25, S2: 5, S3:10 and S4: 20 dS m− 1), and four water application rates (W1:120%, W2:100%, W3:70% and W4:50% of depleted water from field capacity), in a fully randomized factorial design with total of 48 weighted lysimeters. Seed yield was 30% higher when water requirement was fully met (W1 and W2) as compared to treatments where water requirement was partially met (W3 and W4). Crop water response coefficients were found sensitive (Ky= 1.55) to drought induced water stress but tolerant to salinity induced water stress (Ky=0.47). We found that quinoa had a salinity threshold value of ~ 4 dS m− 1(in soil extract) with a slope of 3.4%, (yield loss per dS m− 1increase in salinity) which is classified as moderately salt tolerant crop. We evaluated the combined effects of salinity and water levels on seed yield, concluding that if there is more than one stress factor, the crop will respond to the stress factor having the highest impact (either salinity or water stress). Seed yield under combined salt and water stress for all treatments was well predicted from the separate responses to water and salt stress using the dominant stress response model. Our results indicate that over the range of conditions studied, quinoa water productivity was more dependent on applied water rate than on salinity.
Intrapulmonary Lymph Nodes Positive for Metastasis, in a Typical Multifocal Neuroendocrine Tumor: Case Report.
Authors: Gaviria Habib Jussef Mantilla , Ruiz Willfredy Castaño 
Published: May 2023

Abstract
Background
Multifocal neuroendocrine tumors of the lung are rare, usually having low nodal involvement in early stages. We bring to the literature a case of a typical multifocal carcinoid associated to tumors with intrapulmonary lymph node (IPLN) involvement.
Case presentation:
59-year-old female asymptomatic patient with multiple nodules in the right lower lobe, PET-CT with hypermetabolic nodule, adequate pulmonary function, for which a right lower lobectomy was performed plus intrapulmonary lymph nodes dissection in the fresh surgical specimen. The lymph nodes of stations 11, 12, 13 and 14 were sent to pathology. The pathology laboratory report showed that stations 10, 11, 12 and 13 were negative, but station 14 was positive. Thus, changing the stage from Ia2 to IIb.
Conclusion
This patient had an upstaging because of IPLN were positive for metastasis. The search for a more accurate oncologic staging through intrapulmonary lymph node may allow a more accurate staging and therefore a better treatment for the patient regardless type histology.
Changes in the incidence of community-acquired upper urinary tract infections caused by extended-spectrum beta-lactamase-producing Escherichia coli in Japanese children, 2016-2022
Authors: Horie Akiyoshi , Sasaki Mayu , Nakamura Miku , Harano Shinichi , Moritou Yuuji , Hasegawa Yuki , Fujiwaki Takehisa , Mochizuki Misato , Nariai Akiyoshi 
Published: May 2023

Abstract
Background
Urinary tract infections caused by extended-spectrum beta-lactamase (ESBL)-producing bacteria are increasing worldwide. At our hospital, the number of children hospitalized with upper urinary tract infections (UUTI) caused by ESBL-producing Escherichia coli had been a major problem since 2016.
However, since the start of the COVID-19 pandemic in 2020, the proportion of ESBL-producing E. coli has changed. This study reviewed the trends in admissions of children to the hospital with UUTI caused by E. coli.
Methods
This retrospective study included patients who were hospitalized in the pediatric department of Matsue Red Cross Hospital with UUTI caused by E. coli. Medical and hospital records were reviewed to assess patient characteristics, antimicrobial use density, and days of antibiotic therapy at the hospital from January 1, 2016 to December 31, 2022.
Results
Over the study period, 80 children were admitted to the hospital with their first episode of bacterial UUTI. The total number of children hospitalized in the pediatric department decreased. However, the proportion of children with UUTI per total number of hospitalized children remained stable over the study period. Urine sample analyses showed that the proportion of ESBL-producing E. coli decreased significantly in 2020 to 2022. Antimicrobial use density and days of therapy of oral third-generation cephems was significantly correlated with the proportion of UUTI caused by ESBL-producing E. coli in pediatric patients.
Conclusion
Effective hygiene measures and appropriate use of antibiotics especially, oral third-generation cephems, are effective for reducing the incidence of ESBL-producing bacterial infections.