bluuebunny/crossref_metadata_2025_split huggingface dataset:
A retrospective study on improving the accuracy of radiotherapy for breast cancer patients with lymph node metastasis using Styrofoam
Authors: Jie Li , Yang# Lin , Yao Xiaowei , Xu Linlin , Zhao Lina , Bai Fei 
Published: April 2023

Abstract
Objective: To retrospectively analyze the accuracy of radiotherapy using cone beam computed tomography (CBCT), Styrofoam fixation, and breast bracket fixation in the chest wall target area and supraclavicular lymphatic drainage area (supraclavicular target area) of breast cancer patients.
Methods: A total of 65 patients with postoperative lymphatic metastasis of breast cancer, including 36 cases of Styrofoam fixation and 29 cases of breast bracket fixation, were recruited from March 2021 to August 2022. All the patients underwent CBCT scans weekly, and the set-up errors of the chest wall and supraclavicular target volume were compared and recorded. The planning target volume (PTV) margins of the two groups were calculated using the correlation MPTV = 2.5Σ+0.7σ. The set-up time and comfort satisfaction scores of the two groups were recorded and analyzed. The correlations among errors in each direction were analyzed using the Pearson correlation analysis.
Results: in the left-right direction (X) axis of the chest wall target area between the Styrofoam and breast bracket groups (1.59±1.47mm vs. 2.05±1.64mm, P = 0.012). Two groups compare in the ventrodorsal direction (Z) and bed angle of the supraclavicular target area, the data were (1.36±1.27mm vs 1.75 ±1.55mm,P=0.046;0.47±0.47°vs0.66±0.59°,P=0.006).The PTV margins of the two groups in the three directions of the chest wall target area. The Styrofoam groups were 5.01mm, 5.99mm, and 5.47mm and the breast bracket groups were 6.10mm, 6.34mm, and 6.10mm in the X, Y, and Z directions, respectively. the PTV margins of the supraclavicular target in the three directions. The Styrofoam groups were 3.69mm, 3.86 mm, and 4.28mm and The breast bracket groups were 3.99mm, 3.72 mm, and 5.45mm, respectively. The set-up time of the two groups was 3.4±1.1min and 5.5±3.1min(P=0.007). The subjective comfort satisfaction scores of the two groups were 27.50±1.24 and 25.44±1.23 (P <0.001).
Conclusions: The application of Styrofoam fixation in radiotherapy of breast cancer in the supraclavicular lymph node area has several advantages as compared to breast bracket fixation, including higher positioning accuracy, smaller external expansion boundary, improved work efficiency, and patients’ comfort, which might provide a reference for clinical work.
Research on Prediction and Compensation Strategy of Milling Deformation Error of Aitanium Alloy Integral Blisk Blade
Authors: Li Xiang , Gong Yadong , Ding Mingxiang , Sun Yao , Zhao Jibin , Zhao Yuan , Song Fei 
Published: April 2023

Abstract
Integral blisk blades are typical complex curved structures with small thickness, low stiffness, and complex boundaries. Due to the high material removal rate during the machining process, they are prone to force induced deformation, resulting in significant machining errors. This seriously contradicts the requirements for high design accuracy and surface accuracy in the aerospace industry. Therefore, accurately predicting the distribution pattern of deformation caused by dynamic milling forces during the machining process and proposing reasonable error compensation strategies are urgent issues to be solved in the manufacturing of integral blisk blade. Firstly, this paper establishes a dual flexible force induced deformation calculation model for tool-workpiece coupling based on the analytical-finite element method, and obtains the deformation distribution law of the integral blisk blade machining process according to the principle of static equivalence. Then, based on the finite element deformation prediction model of blades, the selection of blade milling processing methods and parameters was completed with the goal of minimizing machining deformation. Finally, based on the mirror image compensation theory, a reverse reconstruction geometric modelling compensation method is proposed, which uses the blade deformation compensation calculated multiple times to reconstruct the blade contour model, and uses the tool path program containing the deformation error compensation amount is regenerated. The prediction model of blade deformation distribution and the proposed compensation strategy of reverse reconstruction geometric modeling are verified by the milling experiment and profile accuracy measurement experiment of a certain aeroengine integral blisk blade. The results showed that the predicted results were in good agreement with the experimental results, with an average error of 7.96%; The new compensation strategy proposed in this article can significantly reduce the cutting error generated during the machining process and control the error within the designed tolerance range. This study provides theoretical basis and technical support for the large-scale application of virtual digital manufacturing technology to control the deformation of complex thin-walled workpiece during milling in the future.
Effect of bone cement sealing of the intramedullary femoral canal on coagulation status after total knee arthroplasty: a retrospective thromboelastography study
Authors: Chen Jiahao , Wang Hu , Zhang Qiang , Sun Yingjin , Liu Ning , jianning Sun , Feng Shuo 
Published: April 2023

Abstract
Background: The main objective of this study was to investigate whether the use of bone cement in total knee arthroplasty (TKA) has an effect on postoperative coagulation status and bleeding
METHODS: 148 patients who underwent unilateral TKA between September 2019 and February 2023 were collected and divided into Bone and Cement&Bone groups according to whether bone cement was used to seal the bone medullary canal intraoperatively. Routine blood and thromboelastography(TEG) examinations were performed on the day before, the first day and the seventh day after surgery; postoperative bleeding, drainage, transfusion rate and the number of people suffering from deep venous thrombosis (DVT) were recorded.
RESULTS: There were no significant differences between the two groups in terms of baseline clinical characteristics before surgery（p>0.05）。In terms of TEG indicators, the CI of the Bone&Cement group was lower than that of the Bone group on the first postoperative day and on the seventh postoperative day (p<0.005). The CI of patients in the Bone group on the first postoperative day was lower than that of the preoperative day (p<0.05); In terms of blood loss, the total blood loss and occult blood loss were lower in the Bone&Cement group than in the Bone group (p< 0.05). In addition, there was no significant difference in the incidence of postoperative drainage (p:0.255), transfusion rate (p:0.286) and DVT (p:0.576) between the two groups
CONCLUSION: Blocking the intramedullary canal of the femur with bone cement during TKA improves relative postoperative hypocoagulation and reduces postoperative blood loss, although there is no significant effect on transfusion rates, drainage and DVT, but the use of bone cement is clinically beneficial to patients.
TRIAL REGISTRATION: ChiCTR2100051502, 2021/09/24
An in-person survey of the influence of the COVID-19 pandemic on physical function, functional capacity, cognitive function, and mental health among community-dwelling elderly in Japan from 2016 to 2022
Authors: Fukase Yuko , Kamide Naoto , Sakamoto Miki , Ando Masataka , Ichikura Kanako , Shiba Yoshitaka , Tagaya Hirokuni 
Published: April 2023

Abstract
Background The COVID-19 outbreak might have had several effects on the elderly; however, much of the previous research only included self-report, cross-sectional, and online-survey data in the early stage of the pandemic. We conducted a face-to-face survey before and after the COVID-19 pandemic and investigated the influence of the pandemic on several functions.Methods A total of 8 longitudinal surveys were conducted from 2016 to 2022. Physical function was assessed by weight, body mass index, body fat percentage, skeletal muscle mass index, calf circumference, grip strength, knee extension strength, the 5-times chair stand test, and the timed up & go test. Functional capacity was measured using the Tokyo Metropolitan Institute of Gerontology index of competence, cognitive function was measured using the Trail Making Test - A, and mental health was measured using the Geriatric Depression Scale.Results Of a total of 73 participants, 52 (69.9%) were female. The mean age at first participation was 71.82 years (SD = 4.64). The results of the linear mixed model showed that lower-limb muscle strength and body fat percentage of physical function and cognitive function changed significantly before and after the pandemic. Grip strength, functional capacity, and mental health did not change due to the pandemic.Conclusions These functions, which changed before and after the pandemic, might be due to movement restrictions among independent elderly. Although functional capacity did not change, lower-limb muscle strength is important for functional independence. This decline might influence the functional capacity of these individuals in the future.
A study on the difference of physical exercise, manual labor and housework activities among urban and rural elderly population—— Based on CLHLS data
Authors: song keying , zhao zijian 
Published: April 2023

Abstract
This paper analyzes the differences of physical exercise, physical labor and housework activities among the elderly in urban and rural China based on CLHLS data from the 2018 China Aging Health and Longevity Tracking Survey (CLHLS).The results showed that after controlling for population, socioeconomic, lifestyle, self-rated health and external support, there were differences in physical exercise, physical labor and housework participation among the elderly in urban and rural areas (p<0.001).In terms of physical exercise, the urban elderly are more than the rural elderly, in terms of physical labor, the urban elderly are less than the rural elderly, and the urban elderly are less than the rural elderly.Conclusions: After controlling for some important factors, the differences in physical exercise, manual labor and housework activities among the elderly in urban and rural areas are actually smaller than observed.In addition, demographic, socioeconomic, lifestyle, self-rated health and external support variables could not be ignored to explain the differences in physical exercise, manual labor and household activities among the elderly.Moreover, in the dimensions of physical exercise, physical labor and housework, the effects and mechanisms of different variables are also different.
Cellular senescence contributes to tumor growth mediated by regulatory T cells in B-cell Non-Hodgkin's Lymphoma
Authors: xu xuanxuan , Li zhixia , Wang zhitao , Zhu fengfeng , Wang jiyu , Wang huiping , Xiong tao , Tang yuanyan , Zhai Zhimin 
Published: April 2023

Abstract
Background B-cell non-Hodgkin's lymphoma (B-NHL) is a common malignant tumor of the lymphoid immune system. The pathogenic factors are not clear. In recent years, studies have shown that cellular senescence promotes tumor cell immune escape and leads to tumor progression, but how cellular senescence affects B-NHL has not been determined.
Methods There were 12 patients in this study, including 6 cases of B-NHL and 6 cases of reactive lymph node hyperplasia. Senescence-associated β-galactosidase (SA-β-GAL) staining kit was used for aging staining. Regulatory T cells (Tregs) were detected by flow cytometry. The secreted cytokines were detected by enzyme-linked immunosorbent assay kit. Next, we induced the Human diffuse large B-cell lymphoma cell line (LY8) aging model with different concentrations of Tert-butyl hydroperoxide(tBHP) in vitro, and then cultured with normal human monocytes to detect cellular senescence, Tregs and cytokines.
Results Compared with patients with reactive lymph node hyperplasia, the proportion of senescent cells in patients with B-NHL was significantly increased, accompanied by an increase in Tregs and a variety of pro-inflammatory and immunosuppressive cytokines. The aging model of LY8 was induced by different concentrations of tBHP in vitro and co-cultured with normal monocytes. We found that the aging phenomenon was the most obvious in the experimental group with different concentrations of 30μmol/L tBHP, and the levels of related cytokines and Tregs were significantly increased.
Conclusion Cellular senescence and Tregs crosstalk each other, forming a complex tumor microenvironment and promoting the occurrence and development of lymphoma.
Sharia insurance marketing strategy during the Covid-19: PT Prudential life assurance Rembang
Authors: Arum Sari Rully Diyah , Mubarok Ferry Khusnul , Haryati Yuli 
Published: April 2023

Asuransi diartikan sebagai suatu jaminan yang diberikan kepada setiap orang agar terlindung dari risiko – risiko yang akan diderita jika terjadi kejadian yang tidak terduga yang dimaksudkan Judul diatas menguraikan tentang bagaimana strategi pemasaran yang digunakan oleh PT Prudential Life Assurance cabang Rembang sebagai bisnis asuransi yang baru yaitu asuransi berbasis syariah, agar dapat meningkatkan pemasaran di PT Prudential Life Assurance di masa pandemi Covid-19. Berdasarkan hasil penelitian yang telah penulis lakukan, bahwa penjualan produk asuransi mengalami penurunan. Penurunan tersebut dapat terjadi karena kurangnya analisis terhadap perubahan lingkungan pasar. Analisis SWOT dilakukan untuk mengetahui kekuatan, kelemahan, peluang, dan ancaman di PT Prudential Life Assurance cabang Rembang. Setelah mengetahui analisis SWOT PT Prudential Life Assurance cabang Rembang dapat meningkatkan strategi pemasarannya yang kemudian oleh perusahaan dapat diterapkan. Melalui pelatihan dan bersertifikasi seorang tenaga pemasar dituntut untuk memasarkan produk berbasis syariah dengan memperkenalkan produk baru tersebut kepada masyarakat dan mengajak calon nasabah untuk berasuransi yang bersyariah.
Health risk assessment of the heavy metals at wastewater discharge points of textile industries in Tongi, Shitalakkhya, and Dhaleshwari, Bangladesh
Authors: Uddin Mohsin , Alam Faisal Bin 
Published: April 2023

AbstractPollution of industry-adjacent surface water bodies has become a major threat to the environment in Bangladesh. This study examined the health risks of concentrated heavy metals in Tongi, Shitalakkhya, and Dhaleshwari, which receive effluents from wastewater treatment plants. Samples were analyzed for heavy metals such as lead, cadmium, iron, magnesium, manganese, zinc, copper, chromium, and nickel. At all the locations, only Zn, Cu, and Ni did not exceed the Bangladesh standard for drinking water. The health risk was estimated using the hazard quotient (HQ) technique. There was a threat of health risks resulting from the exposure through ingestion, with Pb, Cd, Fe, Mg, and Cr being the main contributors. The orders of decreasing values of mean HQ were Mg &gt; Pb &gt; Fe &gt; Cr &gt; Cd, Mg &gt; Fe &gt; Pb &gt; Cr &gt; Cd, and Cr &gt; Mg &gt; Pb &gt; Fe &gt; Cd via oral intake for both adults and children at Tongi, Shitalakkhya, and Dhaleshwari, respectively. For dermal intake, the mean HQ for only chromium at Dhaleshwari exceeded the limit for both groups. The results emphasize the need for enhancement, proper operation, and maintenance of wastewater treatment facilities in order to meet the discharge quality standard.
Numerical simulation analysis of heat and mass transfer of saline wastewater in a falling film evaporation tube based on different inlet modes
Authors: Kong Xiang Cheng , Liu You Le , Li Hua Shan , Xue Jian Liang , Liu Bing , Cheng Dong Le , Gao Yu , Xiao Xin Feng 
Published: April 2023

Abstract

Falling film evaporation technology is widely used in the treatment of salt-containing wastewater in coal chemical industry. However, there is still a lack of research on the inlet method of vertical falling film evaporation tubes. In this paper, the heat and mass transfer processes of saline wastewater under vertical and tangential inlets were investigated using numerical simulations. On this basis, the differences in flow and heat transfer processes between saline wastewater and pure water under tangential inlet were investigated. The results showed that the flow velocity of saline wastewater with a falling film evaporation tube in a tangential inlet mode was larger. Meanwhile, the turbulence in this way was more intense and the fluid temperature in the vertical tube was higher. Saline wastewater has higher temperature and smaller liquid volume fraction than pure water liquid membrane in the range of 193–1,000 mm from the inlet. The use of tangential inlet method to treat salt-containing wastewater has higher evaporation efficiency and is a very effective way to guide the improvement of heat transfer efficiency.
Homens trans no esporte:
Authors: Ferreira Noah Kyon Borges Caldas , Garcia Rafael Marques 
Published: April 2023

Na atualidade, é possível tomar o esporte como uma via de inclusão bastante significativa, porém nos propusemos a verificar como o esporte se apresenta quando se trata da população de pessoas transexuais, mais precisamente no Fut7. Objetivamos analisar o processo de inserção e atuação de jogadores de Fut7 transexuais do time carioca BigTboys, tendo como questão: como se dá o acesso ao esporte, mais especificamente no Fut7, por homens trans? Foi elaborado um questionário misto (perguntas fechadas e abertas) para coleta de dados, cujas respostas foram organizadas em sínteses, que foram posteriormente analisadas pela técnica de análise de discurso. Como resultados, identificamos que os jogadores transexuais do time de Fut7 têm no esporte, mais precisamente no time BigTboys, um local de acolhimento, pertencimento, cuidado e bem-estar. Porém, percebemos que num cenário mais amplo a inclusão no esporte não ocorre de forma pacífica em função do gênero e da sexualidade, tornando-se importante alertar sobre a necessidade de mais pesquisas acadêmicas acerca do tema com o intuito de tornar o esporte mais inclusivo e um aliado, não um local intimidador, para homens não cisheterossexuais.
A Cost-effective and Green Synthesis of Isothiocyanates
Authors: Li Qinsheng , Xiong Junhao , Liao Jiahao , Huang Qinghua , Hu Zhongyu , Yang Yuping , Xiong Zhenhua , Cheng Chuanjie 
Published: April 2023

Abstract:
Irritant, expensive, or toxic desulfurating agents are usually used in the synthesis of isothiocyanates
from amines, CS2, and appropriate bases, accompanied by a tedious workup. A more practical
and green method has been developed. Cheap and non-toxic CaO was used as both a base and a
desulfurating agent in the synthesis of isothiocyanates. Both alkyl and aryl isothiocyanates are easily
synthesized in moderate to high yield from amines, CS2, and CaO under mild conditions. A simple
and practical synthetic approach for isothiocyanates from amines, CS2, and CaO was developed. CaO
acts as both a base and a desulfurating agent in the reactions, simplifying the reaction system and reducing
cost as well as side products. Moderate to high yields were obtained at room temperature in 48
hours which included alkyl and aryl isothiocyanates.
Two-dimensional MXene Nanomaterials: Preparation, Structure
Modulation and the Applications in Electrochemical Energy Storage
Authors: Chen Yingchun , Yu Bei , Peng Lingling 
Published: April 2023

Background:
MXenes have attracted intensive attention owing to their unique twodimensional
(2D) layered structure, high specific surface area, excellent conductivity, superior surface
hydrophilicity, and chemical stability. In recent years, selective etching of the A element layers from
MAX phases by fluorine-containing etchants (HF, LiF-HCl, etc) is a common method to prepare multilayered
MXene nanomaterials (NMs) with plentiful surface terminations. At present, many studies have
been reported on the use of fluorine-free etchants (NaOH, ZnCl2, etc) to etch MAX phases. The properties
of MXene NMs are dependent on their structures.

Objective:
The purpose of this review is to focus on a comprehensive and systematical survey on the
preparation, structure modulation, and applications of MXene NMs in electrochemical energy storage
devices, including supercapacitors, lithium-ion battery, sodium-ion battery, potassium-ion battery, and
aluminum-ion battery.

Methods:
Extensive information related to the preparation and applications of 2D MXene NMs for electrochemical
energy storage and their associated patents were collected. This review highlights the recently
reported 2D MXene NMs which are used in supercapacitor and various metal ion.

Results:
It is found that the preparation methods have great impacts on the layer spacing and surface
terminations of MXenes, consequently affecting their performance. Hence, this paper summarizes the
research progress of the preparation strategies, layer spacing and surface termination modulation of
MXene NMs.

Conclusion:
The applications of 2D MXene NMs in electrochemical energy storage are outlined. The
forward-looking challenges and prospects for the development of MXenes are also proposed.
Health Tourism Prevalence among Western Balkans Citizens During the COVID-19 Pandemic Period
Authors: Maljichi Drita , Tahirbegolli Bernard , Maljichi Driton , Tahirbegolli Iliriana Alloqi , Spier Troy E. , Kulanić Ahmed , Nasufi Irida Agolli , Kovač-Orlandić Milica 
Published: April 2023

Background:
This study seeks to evaluate the prevalence of and the association between receiving medical care abroad and the level of trust that citizens from the Western Balkans—Albania, Bosnia and Herzegovina, Kosovo and Montenegro—have in their healthcare systems.

Methods:
The study is cross-sectional and was carried out during three months (July 25-October 30, 2021) through a self-reported questionnaire administered through the Google Forms platform. The study included approximately two-thousand citizens (N=2,356) aged eighteen (18) to seventy (70).

Results:
More than one-third (37.2%) of respondents stated that they or a relative had received healthcare services abroad during the last twelve (12) months. Citizens of Montenegro had the highest prevalence of receiving healthcare services abroad at 43.8%, followed by those from Bosnia and Herzegovina at 39%. No statistically significant difference was found in the level of trust in the healthcare system in the country between those who received healthcare services abroad (4.41±2.88) (out of 10) and those who did not (4.48±2.81) (t= -0.587, p=0.557).

Conclusion:

We ultimately conclude that more than one-third of the participants in our study have traveled abroad for healthcare purposes, with females, those living in urban areas, and those who have previously had a negative healthcare experience in their home country all being more likely to rely on health tourism.