bluuebunny/crossref_metadata_2025_split huggingface dataset:
Revealing the degradation pathways of layered Li-rich oxide cathodes
Authors: He Xin , Liu Zhimeng , Zeng Yuqiang , Tan Junyang , Wang Hailong , Zhu Yudong , Geng Xin , Guttmann Peter , Hou Xu , Yang Yang , Xu Yunkai , Cloetens Peter , Wei Yinping , Lu Jun , Li Jie , Liu Bilu , Winter Martin , Kostecki Robert , Lin Yuanjing 
Published: August 2023

Abstract

Layered Li-rich transition metal oxides (LRTMO) are one of the most promising cathode candidates for high energy density lithium batteries due to the redox contributions from transition metal (TM) cations and oxygen (O) anion. However, their practical application is hindered by gradual capacity fading and voltage decay. Although oxygen loss and phase transformation have been widely recognized as primary factors for these drawbacks, the structural deterioration and chemical rearrangement of LRTMO during battery operations, and the kinetic and thermodynamic evolution, remain unclear. Herein, we comprehensively investigate the morphological, structural, and oxidation state evolutions from the individual atoms to secondary particles. By means of nano- to micro-scale characterizations, distinct structural changing pathways associated with different intra-particle heterogeneous reactions are identified. Substantial O-defects are formed through the particle by slow electrochemical activation, accompanied with oxygen release triggering progressive phase transformation on surface and formation of nano-voids in bulk. The ultra-fast heterogeneous Li- (de)intercalation often leads to O-distortion dominated lattice displacement, TM-ions dissolution, and Li-sites variation. These inhomogeneous and irreversible structural changes are responsible for first-cycle Coulombic inefficiency, and ongoing particle cracking and expansion in the following cycles.
Expectations of platform workers in five Ibero-american countries
Authors: Cifuentes Diana Milec , Viego Valentina , Boscon Daniela Campos Bahia , Ansoleaga Maria Elisa , Llosa Jose Antonio 
Published: August 2023

Abstract

This article aimed to analyze the expectations of digital platform workers in delivery and transportation services in Argentina, Brazil, Colombia, Chile, and Spain about the future of their work. Based on a mixed method, we analyse responses to an open-ended question from a questionnaire applied in 2021 to 971 platform workers in the five chosen countries. We use content analysis and statistical tests to classify and compare results. We find that workers’ expectations differ according to living and working conditions. Favorable expectations focused on the possibility of finding new job opportunities, whereas pessimistic expectations are based on uncertainties and low pay. We discuss the ambivalence in workers’ expectations and their heterogeneity between countries. We found more favorable expectations than expected based on objective contracting conditions. All countries have a common transversal element as workers conceive platforms as transitional work.
Weight change following diagnosis with psychosis: A retrospective cohort study in Greater Manchester, UK
Authors: Heald Adrian , Daly Chris , Warner-Levy John Julian , Williams Richard , Meehan Cheyenne , Livingston Mark , Pillinger Toby , Hussain Lamiece , Firth Joseph 
Published: August 2023

Abstract
Introduction
Weight gain in the months/years after diagnosis/treatment of severe enduring mental illness (SMI) is a major predictor of future diabetes, dysmetabolic profile and increased risk of cardiometabolic diseases.
There is limited data on the longer-term profile of weight change in people with a history of SMI and how this may differ between individuals.
We here report a retrospective study on weight change over the 5 years following an SMI diagnosis in Greater Manchester UK, an ethnically and culturally diverse community, with particular focus on comparing non-affective psychosis (NAP) vs affective psychosis (AP) diagnoses.
Methods
We undertook an anonymised search in the Greater Manchester Care Record (GMCR).
We reviewed the health records of anyone who had been diagnosed for the first time with first episode psychosis, schizophrenia, schizoaffective disorder, delusional disorder (non-affective psychosis=NAP) or affective psychosis (AP). We analysed body mass index (BMI) change in the 5-year period following the first prescription of anti-psychotic medication. All individuals had taken an antipsychotic agent for at least 3 months. The 5-year follow-up point was anywhere between 2003 and 2023.
Results
We identified 9125 people with the diagnoses above. NAP (n=5618; 37.3% female) mean age 49.9 years; AP (n=4131; 60.5% female) mean age 48.7 years. 27.0% of NAP were of non-white ethnicity vs 17.8% of BAP individuals.
A higher proportion of people diagnosed with NAP were in the highest quintile of social disadvantage 52.4% vs 39.5% for AP. There were no significant differences in baseline BMI profile. In a subsample with HbA1c data (n= 2103), mean HbA1c was higher in NAP at baseline (40.4mmol/mol in NAP vs 36.7mmol/mol for AP).
At 5-year follow-up, there was similarity in both the overall % of individuals in the obese ≥30kg/m2 category (39.8% NAP vs 39.7% AP), and % progressing from a normal healthy BMI transitioned to obese / overweight BMI (53.6% of NAP vs 55.6% with AP). 43.7% of those NAP with normal BMI remained at a healthy BMI vs 42.7 % with AP. At 5-year FU for NAP, 83.1% of those with BMI ≥30kg/m2 stayed in this category vs 81.5% of AP.
Conclusion
The results of this real-world longitudinal cohort study suggest that the changes in BMI with treatment of non-affective psychosis vs bipolar disorder are not significantly different, while 43% maintain a healthy weight in the first 5 years following antipsychotic prescription.
The Long-Term Impact of Household Debts on Household Consumption in the Context of High Housing Prices in China
Authors: Xie Zhuyun , Liu Yue , Tajeddini Kayhan , Kumari Sonia , Xu Lu 
Published: August 2023

Abstract
It is important to understand the factors influencing consumption patterns in China, a rapidly growing economy with high household debt. The main objective of this study is to investigate the long-term impact of household debt on household consumption using panel data from 2014 to 2020. Data for this paper is mainly derived from the China Family Panel Studies (CFPS) database for the four periods of 2014, 2016, 2018, and 2020 to examine the impact of household debt on current consumption and its long-term effect on consumption. An econometric model was adopted to analyze the data. The findings demonstrate that total household debt significantly lowers long-term household consumption. In contrast, housing debt has a more significant crowding-out effect on household consumption, and non-housing debt has no significant impact. These findings imply that higher levels of debt cause decreased consumption by forcing households to allocate a larger portion of their income toward house financing. In addition, we also find that increasing rural families’ leverage will have a greater negative impact on household consumption. These findings propose that the measures to address the issue of high household debt, particularly housing debt, are necessary to promote sustainable consumption patterns and support the well-being of households. The findings of the study highlight the significance of considering rural families' unique circumstances when developing debt management measures.
Novel nano-siRNA delivery system loaded with anti-ESR1 siRNA for ovarian cancer clinical and nursing value assessment
Authors: Zhang Jin , Fan Wenhui 
Published: August 2023

Abstract
Globally, ovarian cancer is one of the most common cancers in women and one of the most common causes of cancer death. Researchers have been committed to investigating new treatment methods for ovarian cancer. In the present study, a new nano-siRNA delivery system loaded with anti-ESR1 siRNA was designed and synthesized. Its clinical and nursing value for ovarian cancer was evaluated, and the related mechanism was explored. First, the inhibitory activity of the new compound on the viability of ovarian cancer was measured via CCK-8 assay. Second, the relative expression of the estrogen receptor in the ovarian cancer cells was determined through real-time RT-PCR detection. Results revealed that the novel nano-siRNA delivery system loaded with anti-ERα siRNA could negatively regulate the expression of ERα and suppress the progression of ovarian cancer.
A Novel de novo Design Study of Potent SARS-CoV-2 Main Protease Inhibitors Based on Reinforcement Learning and Molecular Docking
Authors: Qu Hanyang , Wang Shengpeng , He Mingyang , Wu Yuhui , Yan Fei , Liu Tiaotiao , Zhang Meiling 
Published: August 2023

Abstract
The outbreak of coronavirus disease 2019 (COVID-19) SARS-CoV-2 has caused widespread panic in the world and has mutated at an extremely rapid rate and thus there is an urgent need for the development of COVID-19 inhibitors. In this study, we used a de novo design method, which integrates a recurrent neural network, reinforcement learning and molecular docking to generate inhibitors of SARS-CoV-2 main protease. Approximately 30,000 molecules were generated after a 120h generation process, and multiple physicochemical filters and molecular docking scores were used for further screening. Finally, five molecules were selected as drug candidates, and their binding stability was verified by molecular dynamics simulation and binding free energy analysis. The results showed that these molecules could be used as candidates for further generation and testing against SARS-CoV-2. Besides, a pharmacophore model based on superior molecules was constructed to provide a reference for subsequent drug screening.
Mid-infrared Imaging spectroscopic measurements of C2H4 frost simulating the outer solar system environments
Authors: Koga Ryoichi , Negishi Shohei , Zhao Biao , Li Yuan , Ito Fumiyuki , Kasaba Yasumasa , Hirahara Yasuhiro 
Published: August 2023

Abstract
In the dense and cold atmosphere of Titan, the presence of C2H4 haze has been confirmed by the observations of satellite explorers. In the present study, an original cryogenic experimental equipment was developed to simulate the low-temperature solid formation of C2H4 in combination with in-situ infrared spectroscopic measurements to understand the spectral band properties of C2H4 condensation in the haze component of Titan. As a result, out-of-plane bending vibration ν7 of solid-phase C2H4 located at λ ~ 10.5 µm was successfully detected with high sensitivity, and two-dimensional spectrographs of C2H4 at low temperatures were obtained. The obtained spectra of C2H4 can be fitted to the double Lorentzian function with various heights, central wavelengths, and full widths at half maximum of the two-component Lorentzian functions. They were classified into three types whose spectral shapes are similar to the amorphous, metastable crystal, and crystalline forms obtained by the previous laboratory experiment.
Finance, Growth and Inequality: Does Source of Finance Matter?
Authors: Das Pranab Kumar , Ganguli Bhaswati , Marjit Sugata , Roy Sugata Sen 
Published: August 2023

Abstract
Using India Human Development Survey (IHDS) data for two rounds the study aims to assess the role of source of finance in the growth process and the outcome on inequality of income and asset. The most important result of the paper is that source of loans – formal (banks) or informal (moneylenders) have no role on the rate of growth of household asset and income. The difference for the respective rates of growth lies only in the level, i.e. intercept term across main sources of borrowing and across poverty groups. Inequality of income increases independent of the source of borrowing, though the poor households are worse off in general. This questions the conventional wisdom regarding the policy aimed at financial inclusion. Indifference of rate of growth across sources of borrowing is due to the fact that informal sector interest rate is the marginal cost of borrowing. This result can be generalised for any number of sources of borrowing.
JEL Codes: C350, E2, E43,,E5, G210, O11.
The prognostic utility of the AJCC staging 8th edition in predicting the survival of human papillomavirus associated oropharyngeal squamous cell carcinoma: A population-based study using the SEER database
Authors: Kim Su Il , Lee Jung Woo , Eun Young-Gyu , Lee Young Chan 
Published: August 2023

Abstract
Background: The American Joint Committee on Cancer (AJCC) staging 8th edition introduced major changes in the TNM staging of oropharyngeal squamous cell carcinoma (OPSCC) based on the human papillomavirus (HPV) status. We aimed to comprehensively evaluate the discriminatory power in the survival of patients with HPV (+) OPSCC between AJCC staging 7th and 8th edition using a large population database.
Methods: A total of 7448 patients with HPV (+) OPSCC were enrolled using the Surveillance, Epidemiology, and End Results database between 2010 and 2016. Patients diagnosed with OPSCC and tested positive for HPV with information on the TNM staging according to the AJCC staging 7th edition were selected. Next, T-, N-, and clinical staging were reconstructed based on the AJCC staging 8th edition. Survival probabilities in each edition were estimated and compared using Kaplan–Meier plots.
Results: Of the 7448 patients, 6960 patients (93.44%) were down-staged from the 7th to the 8th edition in patients with HPV (+) OPSCC. Overall survival was significantly associated with clinical staging according to the 7th and 8th editions of the AJCC. Additionally, the staging system according to the 8th edition demonstrated more discriminatory power than that according to the 7th edition, regardless of the primary subsites. Clinical staging according to the AJCC 8th edition compared to that of the 7th edition was an independent prognostic factor in patients with HPV (+) OPSCC.
Conclusion: This large population-based study emphasizes the advantages of the new classification system for predicting survival in patients with HPV (+) OPSCC.
Deep Discretized Deterministic Policy Gradient Based Resource AllocationConsidering Network Slicing and Device-to-Device Paradigms
Authors: Lopes Hudson Henrique de Souza , Vieira Flávio Henrique Teles , Soare Telma Woerle de Lima 
Published: August 2023

Abstract
Next-generation networks, such as those beyond 5th generation (B5G) and 6th generation (6G) generation, have diverse network resource demands that imply significant changes in the architecture and infrastructure of telecommunication networks. Network slicing (NS) is considered a candidate technology, where a single network infrastructure is divided into (virtual) multiple slices to meet different service requirements. The idea of combining device-to-device (D2D) and NS can improve spectrum utilization, thereby providing better performance and scalability. This paper addresses the challenging problem of dynamic resource allocation in wireless network slices with D2D using deep reinforcement learning (DRL) techniques. More specifically, we propose an approach named DDPG-KRP based on deep deterministic policy gradient (DDPG) with K-Nearest Neighbors (KNN) and Reward Penalization (RP) for undesirable action elimination to determine the resource allocation policy maximizing long-term rewards. The simulation results show that the DDPG-KRP is a promising solution for resource allocation in next-generation wireless networks, outperforming other considered DRL algorithms.
A taxonomic revision of the South American trilobite cockroaches of Parahormetica Brunner von Wattenwyl, 1865 (Blattodea: Blaberidae), with description of Parahormetica museunacional sp. nov. from the Atlantic Forest
Authors: Polizeli Leonardo , Pinto Ângelo Parise 
Published: August 2023

Abstract
The taxonomically intricate genus of trilobite cockroaches, Parahormetica Brunner von Wattenwyl, 1865, is revised based on a comparative morphological analysis. The goals of this study are to review the nomenclature, propose hypotheses about specific delimitation and provide diagnoses to allow identification of the taxonomic units in the genus. Based on the revised status of Parahormetica we transferred Parahormetica hylaeceps Miranda-Ribeiro, 1936 and Parahormetica punctata Saussure, 1873 to the genus BionoblattaRehn, 1940. Therefore the genus include now four species of giant cockroaches which are predominantly distributed on the Atlantic Forest: Parahormetica bilobata (Saussure, 1864), Parahormetica cicatricosa Saussure, 1869, Parahormetica monticollis (Burmeister, 1838), and Parahormetica museunacional sp. nov. Diagnoses, key, distribution maps, images of living, non-type and type specimens are made available. Our results make clear that the status and limits among Brachycolini genera pending a full revision.
Anoikis-related Signature Predicts Prognosis and Characterizes Immune Landscape of Ovarian Cancer
Authors: Yang Jiani , Zhang Yue , Cheng Shanshan , Xu Yanna , Wu Meixuan , Gu Sijia , Xu Shilin , Wu Yongsong , Wang Chao , Wang Yu 
Published: August 2023

Abstract
Ovarian cancer (OV) is the most lethal gynecological malignancy worldwide, with high recurrence rates. Anoikis, a newly-acknowledged form of programmed cell death, plays an essential role in cancer progression, though studies focused on prognostic patterns of anoikis in OV are still lacking. We filtered 32 potential anoikis-related genes (ARGs) among the 6406 differentially expressed genes (DEGs) between the 180 normal controls and 376 TCGA-OV samples. Through the LASSO-Cox analysis, a 2-gene prognostic signature, namely AKT2, and DAPK1, was finally distinguished. We then demonstrated the promising prognostic value of the signature through the K-M survival analysis and time-dependent ROC curves (p-value < 0.05). Moreover, based on the signature and clinical features, we constructed and validated a nomogram model for 1-year, 3-year, and 5-year overall survival, with reliable prognostic values in both TCGA-OV training cohort ( p-value < 0.001) and ICGC-OV validation cohort (p-value = 0.030). We evaluated the tumor immune landscape through the CIBERSORT algorithm, which indicated the upregulation of resting Myeloid Dendritic Cells (DCs), memory B cells, and naïve B cells and high expression of key immune checkpoint molecules (CD274 and PDCD1LG2) in the high-risk group. Interestingly, the high-risk group exhibited better sensitivity toward immunotherapy and less sensitivity toward chemotherapies, including Cisplatin and Bleomycin. Especially, based on the IHC of tissue microarrays among 125 OV patients at our institution, we reported that aberrant upregulation of DAPK1 was related to poor prognosis. Conclusively, the anoikis-related signature was a promising tool to evaluate prognosis and predict therapy responses, thus assisting decision-making in the realm of OV precision medicine.
Multi-model evidence of future tropical Atlantic precipitation change modulated by AMOC decline
Authors: Cerato Giada , Bellomo Katinka , D'Agostino Roberta , von Hardenberg Jost 
Published: August 2023

Abstract
Projections from climate models reveal a significant inter-model spread in the anticipated changes in tropical Atlantic rainfall by the end of the 21st century, including alterations to the Intertropical Convergence Zone (ITCZ) and monsoonal regions. While existing studies have identified various sources of these uncertainties, our research uncovers, for the first time, a prominent role played by the inter-model spread in the decline of the Atlantic Meridional Overturning Circulation (AMOC). Through an examination of 30 climate model simulations for the 21st century (using the ssp5-8.5 scenario) from the CMIP6 archive, we demonstrate that models projecting a more substantial AMOC decline exhibit an equatorward shift of the ascending branch of the Atlantic Hadley circulation, resulting in a southward displacement of the ITCZ. Conversely, models projecting a relatively smaller AMOC decline depict an intensified hydrological cycle but do not indicate any displacement of the ITCZ. Our findings have crucial implications for comprehending the mechanisms driving future changes in tropical Atlantic precipitation, underscoring the central role played by the AMOC.
The effect of coting peach (Prunus persica L.) on increasing shelf life after harvesting
Authors: Shajari Sima , Madani Hamid , Pourhoseini Leila , Paknejad Farzad , Ilkaee Mohammad Nabi 
Published: August 2023

Abstract
Considering the high waste after peach harvest, it is very important to provide suitable solutions to increase the shelf life of this fruit after harvest. One of the ways to increase the shelf life of fruits after harvesting is to use nature-friendly substances such as vegetation and the use of hormones. For this purpose, an experiment was conducted to investigate the effect of vegetation cover in a factorial form in a completely randomized design in four replications on peach (Prunus persica L.). Research treatments included salicylic acid at three levels: control (no consumption), 1 mM and 2 mM, aloe vera gel at three levels control (no consumption), 20% and 30%, clove extract (Syzygium aromaticum) at three levels of no consumption (control), 150 ppm and 300 ppm. The results of this research showed that the use of coating fruits with plant extracts and salicylic acid increased the shelf life and quality of peaches after harvesting compared to the control (no consumption), so the highest fruit weight 24.65 g was seen in salicylic acid 2 mM, 73.68 g aloe vera gel 30%, and 62.75 g clove extract 300 ppm. The lowest this index was observed in control. The highest total antioxidant 509.75 m mol.l− 1, was observed in the interaction of salicylic acid 2 mM + aloe vera gel 30% + clove extract 300 ppm. The lowest of this index 320.53 m mol.l− 1 was seen in control.
A hearing preservation technique for acoustic neuroma resection via retrosigmoid sinus approach
Authors: Zeng Lang , Zeng Lingcheng , Chen Kun , Chen Rudong , Li Hua , Yu Jiasheng , Yang Hongkuan 
Published: August 2023

Abstract
Background: Acoustic neuroma, also known as vestibular schwannoma, is a non-cancerous tumor that accounts for up to 90% of all cerebellopontine angle (CPA) tumors. The treatment for acoustic neuroma typically involves surgical removal of the tumor. The most common surgical approach is translabyrinthine surgery, which involves resection of the tumor in the inner auditory canal (IAC) and in the cerebellopontine horn area. Adequate excision of the IAC is essential for complete tumor removal from this area. However, this type of surgery can result in injuries to the inner ear, leading to hearing loss and balance problems. Advances in surgical techniques for IAC resection have improved canal exposure without causing significant damage to the inner ear.
Objective: Preoperative imaging, such as three-dimensional (3D) high-resolution computed Tomography (HRCT), can be used to calculate the optimal resection angles for IAC excision. These images provide detailed information on the location and size of the tumor, as well as the surrounding structures in the ear.
Methods: This study included 256 patients diagnosed with unilateral acoustic neuroma who underwent HRCT scans before and after surgery. Images were acquired and analyzed using the Syngo 2008G workstation. IAC was then assessed and surgery was planned based on the acquired HRCT images.
Results: The optimal angle of grinding for the labyrinth was 42.3°, which allowed for IAC resection in 76.3% patients and total tumor resection in 94.1% patients as well as ensured the integrity of the labyrinth during the surgical procedure.
Conclusion: We hope that our method of calculation will serve as a useful guide for practicing surgeons when performing this complex surgery. We anticipate that with the application of endoscope-assisted neurosurgical technique and electrophysiological monitoring, the preservation of facial and vestibulocochlear nerve functions in acoustic neuroma surgery will be further improved.