bluuebunny/crossref_metadata_2025_split huggingface dataset:
Competency-Based Approach in Teaching Сardiopulmonary Resuscitation
Authors: Perepelitsa S. A. 
Published: December 2022

Aim of the study: to develop an additional professional competence «Emergency care in cardiac arrest» and to evaluate a set of tools for its development among the graduating students majoring in general medicine (code 31.05.01).Material and methods. The study was done in two stages. During the first stage, within the framework of PC (professional competence)-11 «Readiness to participate in providing first medical aid in conditions requiring urgent medical intervention» an additional professional competence «Emergency care in cardiac arrest» was developed with the definition of performance assessment. During the second one, the scientific research was conducted at the medical institute of the Immanuel Kant Baltic Federal University during the study of Anesthesiology, resuscitation, and intensive care, which has been included in the block 1 discipline (module) list, being a basic part of the General Medicine curriculum (code 31.05.01). The study involved 140 six-year students majoring in general medicine (code 31.05.01). The students were divided into two groups. The main group included 80 students who studied in 2021 (average age 25±1.5 years), while the control group comprised 60 participants who studied in 2019 (average age 25.9±1.6 years, retrospective analysis).Results. An additional professional competence «Emergency care in cardiac arrest» and its stratified structure have been developed. Specific elements were elaborated for each component stratum. Based on the developed elements, which were mastered by the student in the process of training, the necessary competence was developed. The novel pedagogical technologies in the curriculum contributed to more effective learning and development of the competence. The levels of development of additional professional competence «Emergency care in cardiac arrest» differed between the groups. Most students in the control group had a threshold level of competence. The basic and advanced levels of competence were significantly higher among the students in the main group compared with the control group (P<0.05).Conclusion. We have shown the necessity of developing an additional professional competence «Emergency treatment in case of cardiac arrest» within the «Readiness to participate in providing first medical aid in conditions requiring urgent medical intervention» PC-11. We have successfully implemented and validated in practice the system of development of additional professional competence using pedagogical innovations, including those based on advanced information and communication technologies.
Birth of the She-Devil
Authors: Downie-Greenidge Dexter 
Published: December 2022

At the turn of the century, lesbian characters were appearing in popular American media ranging from television to film. However, many of these depictions were far from supportive. Instead, the lesbian identity of characters in American cinema harbored negative stereotypes that acted as an attack on the third wave feminist movement.
This essay analyzes depictions of lesbians in film at the end of the 20th century as it relates to the third wave feminist movement of the 1990s. More specifically, it argues that stigmatized depictions of lesbians in American cinema reproduced the underlying anxieties of the third wave feminist movement. Through the analysis of two films: Election (1999) and Mean Girls (2003), as well as the feminist theory of bell hooks, this essay explores the fears and anxieties of the revitalized feminist movement. Both films served as a backlash against the feminist movement by using skewed depictions of lesbians to further establish negative emotions towards the movement. These political and sociological anxieties of the feminist movement developed into exaggerated characteristics within lesbian supporting characters. As a result, stigmatized depictions of lesbians delegitimized their role as leaders of the third wave feminist movement.
Improving Time to Stat Intravenous Antibiotic Administration: An 8-Year Quality Initiative
Authors: Miller Hannah , Tseng Ashlie , Lowerre Tracy , Schefft Matthew , Muñoz Jose , Pedigo Sheila , Silverman Jonathan 
Published: December 2022

BACKGROUND AND OBJECTIVES:
Prompt antibiotics have been shown to improve outcomes in pediatric sepsis, which continues to be a leading cause of death in children. We describe the quality improvement (QI) efforts of a single academic children’s hospital to improve antibiotic timeliness.

METHODS:
Using the electronic health record, we report time from order to the administration of stat intravenous (IV) antibiotics from 2012 to 2020 using statistical process control charts. We describe QI interventions initiated over the study period. These include the formation of a Pediatric Sepsis Committee, routine use of automated dispensing machines for stat IV antibiotics, creation of sepsis order sets, manual and automated sepsis screening implementation, participation in national sepsis QI collaboratives, creation of difficult intravenous access guidelines, and an automated notification system for charge nurses. As a balancing measure, we assessed stat IV antibiotic use normalized to total emergency department visits and inpatient days.

RESULTS:
Multiple quality improvement interventions were initiated and sustained under the direction of the hospital Pediatric Sepsis Committee. We improved our stat IV antibiotics given within 1 hour of order from 33% in 2012 to 77% in 2019 and maintained this through the end of the study period in July 2020.

CONCLUSIONS:
By using a multipronged quality improvement approach, we demonstrated consistent and sustained improvement in the timely administration of stat IV antibiotics over an 8-year period at our institution. Further study is needed to assess whether this is associated with reduced length of stay or improved survival in children with sepsis.
Cardiooncology: current status of the issue, interdisciplinary interaction
Authors: Tsyrenov D. D. , Tsyrenova E. B. , Sysoev S. Yu. 
Published: December 2022

Current methos of treatment of oncological pathology significantly increase survival rates and patients’ lifespan. However, treatment of malignant tumors leads to development of adverse reactions decreasing its effectiveness and negatively affecting quality of life and survival. It was shown that short- and long-term cardiovascular complications significantly affect the results of therapy.The article presents data on current scientific research in cardio-oncology touching on the problems of cardiotoxicity, concomitant cardiological disorders in oncological patients, cardiac rehabilitation, and patients’ quality of life. The importance of multidisciplinary approach in the context of reducing the risk of cardiovascular complications is demonstrated.
Insulin-like growth factors and their transfer protein in the blood of patients with primary and recurrent soft tissue sarcomas
Authors: Goroshinskaya I. A. , Kaplieva I. V. , Sagatelyan S. A. , Frantsiyants E. M. , Vashchenko L. N. , Pogorelova Yu. A. , Nemashkalova L. A. , Ausheva T. V. , Chernogorov P. V. , Trepitaki L. K. , Sheiko E. A. , Pandova O. V. 
Published: December 2022

Introduction. Soft tissue sarcomas (STS) are rare diseases but their characteristic tendency for recurrence and high mortality dictate the need for the search for prognostic biomarkers for identification of patients with the risk of recurrence. In this context, the system of insulin-like growth factors (IGF) and their insulin-like growth factor-binding proteins (IGFBP) is of interest because it was shown that disruption of the IGF system regulation leads to cancer cell proliferation and migration and chemotherapy resistance.The study objective is to investigate the levels of the IGF system components in blood of patients with primary and recurrent STS.Materials and methods. In total, 54 patients with STS, T2bN0M0, were examined: 12 men and 12 women with primary STS, 10 men and 20 women with recurrent STS, as well as healthy donors (10 men and 10 women). Mean patient age was 63.1 ± 0.9 years. In blood sampled prior to treatment, the levels of insulin-like growth factor 1 (IGF1), insulin-like growth factor 2 (IGF2) and insulin-like growth factor-binding protein 2 (IGFBP2) were measured by ELISA using Mediagnost kits (Germany). Statistical analysis was performed using Statistica 10 software and non-parametric Mann-Whitney test.Results. In primary STS, the levels of IGF1 in men with G3–4 tumors and all women decreased 14- and 20-fold, respectively, compared to healthy donors. Additionally, an insignificant decrease of IGF2 level in men and a decrease of IGF1/IGF2 ratio by the factor of 8.8 in men with G3–4 tumors and by the factor of 24.3 in women were observed. In recurrences, IGF1 level decreased by 40 % in men and by 78–85.5 % in women, while IGF2 level in men with G3–4 tumors decreased by 19 %, in women increased by 21–58 % compared to donors. In women with primary STS and recurrences of G3–4 tumors, IGFBP2 was also elevated. In men with G3–4 tumors, changes in IGFBP2 levels were less significant and had an opposite trend compared to women.Conclusion. STS recurrence is accompanied by imbalance of IGF system components in blood, especially in patients of both sexes with G3–4 tumors. Correlation between increased IGFBP2 level in STS and clinical characteristics of the disease, especially in recurrence, suggest prognostic significance of this molecule.
Analysis of anaplastic lymphoma kinase status in rhabdomyosarcomas: correlation with clinicopathological findings
Authors: Polatova D. Sh. , Botiralieva G. K. , Konovalov D. M. , Babanov B. X. , Sharlay A. S. , Muratov A. N. , Khayitboev S. A. , Zhakhongirova M. A. , Savkin A. V. , Asamedinov N. K. , Nurzhabov A. I. 
Published: December 2022

Introduction. Rhabdomyosarcoma (RMS) is a highly malignant tumor occurring mostly in children. Multimodal therapy is currently promising, however, in patients with high risk (per the stratification scale) low survival rates are observed. There remains a necessity for new possibilities in treatment of this category of patients. Currently, anaplastic lymphoma kinase (ALK) is of considerable interest.Aim. To study expression of ALK as a potential target marker in RMS tissues.Materials and methods. In total, 202 histological RMS blocks were studied. ALK expression was qualitatively measured using immunohistochemistry, and its correlation with histological tumors subtype and patient’s clinical data was evaluated.Results. ALK expression in samples of alveolar RMS was observed in 68 % (41/60) of cases, samples of embryonal RMS in 30 % (26/87) cases, samples of spindle cell/sclerosing RMS in 7 % (1/14) of cases, samples of epithelioid RMS (EpiRMS) in 100 % (2/2) of cases. The study showed correlation between ALK expression and alveolar RMS subtype (р <0.05). In all cases of alveolar RMS with focal ALK D5F3 expression, primarily low or moderate activity levels against anti-myogenin and MyoD1 were observed. ALK-positive samples in the embryonal and spindle cell/sclerosing RMS samples were rarer.Conclusion. The results show that ALK is a promising target for treatment of patients with RMS. Further study of additional genetic aberrations of ALK is planned which could serve as a springboard for development of targeted therapy.
International Special Operations: Concept, Problems of International Legal Support, Countering Challenges and Threats to the Security of States
Authors: Merkushin V. V. 
Published: December 2022

The problem of the implementation of international legal support of special operations is a natural, historically determined and in fact staying beyond the conventional scope of international law. In fact, this is an emerging international custom based on the practice of states in defending national interests in conditions of competing jurisdiction, the legalization of the resources of the «shadow» economy, the spread of the Darknet, the development of new ways and means of warfare and its propaganda. The transnationalization of organized crime, its links with international terrorism, corruption, cybercrime, attempts to build national security systems at the expense of the security of others, the destructive ideology of national domination, accompanied by the «privatization» of state sovereignty by non-state actors, substantiates the practice of implementing special operations against existing and newly created existential challenges and threats to the security of states.The institutionalization of some types of international special operations is obvious, based on the provisions of the UN Charter, multilateral and bilateral agreements, correlates with the activities of regional security systems (Collective Security Treaty Organization — CSTO, North Atlantic Treaty Organization — NATO, League of Arab States — LAS, Organization of American States — OAS, Organization for Security and Co-operation in Europe — OSCE, etc.). The uniqueness of special operations in each specific case, the impossibility of their absolute legal settlement, especially in the military-political sphere, raises the question of the need to revise a number of provisions of the UN Charter as ineffective, the formation of new (unipolar) regional mechanisms for monitoring their implementation, the activation of special scientific research in this area.
Electrolyte abnormalities in patients with perinatal asphyxia
Authors: Prodhan M. Shamsuzzaman , Azad Abu Zafar M. , Shormin Sangida , Kader M. Fazlul , Islam M. D. Monwarul , Das Mrinal Kanti , Hossain Shah M. Moazzem 
Published: December 2022

Background: Perinatal hypoxia is still a major cause of death and disability in developing countries. The infant mortality rate fell from 92 per 1000 live births in 1991 to 43 per 1000 live births in 2011. The aim of the study was to study the electrolyte abnormalities in perinatal asphyxia cases.Methods: This cross-sectional descriptive study was conducted at the Department of Obstetrics and Pediatrics, Rangpur Medical College and Hospital, Rangpur, Bangladesh. The study duration was 2 years, from January 2012 to December 2013. The study was conducted with a total of 120 neonates admitted in the neonatal ward of the study hospital, among which, 60 neonates who had perinatal asphyxia were selected for the case group, and the remaining 60 were age and gender-matched control group participants.Results: In 70% of cases, the mother was Primipara. Among the neonates, 61.67% were male, and 38.33% were female. Only 33% of the case neonates had received regular antenatal check-ups, while 55% had irregular check-ups, and 11.67% had no antenatal checkups. According to the grading of asphyxia, 51.67% of neonates had moderate asphyxia, 20% had mild asphyxia, and 28.33% had severe asphyxia. The comparison of mean values between the case, and control groups showed that both blood urea, and serum creatinine levels were significantly higher among the case group participants, compared to control group values. The mean serum sodium value in mild, moderate, and severe asphyxia were 135.33, 123.42, and 121.53 mmol/l respectively. Mean serum potassium values were 4.11, 4.86, and 5.51 mmol/l respectively. Mean serum creatinine 0.72, 1.00, and 1.83 mg/dl respectively. Mean blood urea levels were 36.17, 58.97, and 88.06 mg/dl respectively. A significant difference was observed between the mean values of serum electrolytes and patients’ asphyxia grade.Conclusions: The study findings can conclude that electrolyte abnormalities are common among perinatal asphyxia patients, and babies with perinatal asphyxia developed hyponatremia, and hyperkalemia at a higher frequency, and significant raises of serum creatinine, and blood urea was also observed, which was proportionate to the severity of asphyxia.
Experience with the midwifery- led continuity care model among female migrant, refugees and asylum seekers in the context of the ORAMMA project
Authors: Kompothanasi Eleni , Charos Dimitrios , Vivilaki Victoria 
Published: December 2022

IntroductionInadequate understanding of medical terminology, poor communication and lack of information affect women's ability to receive adequate care and to establish a relationship with the care provider.MethodsThe sample consists of five immigrants and refugees who lived in a shelter and participated in the ORAMMA program during their pregnancy, in March 2018. In-person interviews were conducted with the participation of an intercultural mediator with an open-ended exploratory questionnaire.ResultsThe women who received care under the ORAMMA program were very satisfied with the provision of prenatal care, they felt very comfortable with the providers talking, communicating, and building a relationship, asking clarifying questions and understanding the reason for their care. Women also felt intimacy, respect, friendship, empathy and confidence to share problems and feelings.
Finally, empowering them to familiarize themselves with the health care system has proven to be useful enough for women to be able to care for themselves.ConclusionsThe provision of prenatal and perinatal care to refugee and migrant women offers significant benefits to pregnancy. Therefore, the provision of the ORAMMA program to migrant and refugee women is vital.
Message from the Editor in Chief
Authors: Laborda Jesus Garcia 
Published: December 2022

Dear reader,
We are elated to present to you Volume 9, Number 1, 2022 issue of the Selected Papers of the 14th World Conference on Educational Sciences (WCES-2022), which was held online from the 3rd to the 5th of February 2022, in Paris, France. This issue aimed to present the papers that were selected from the myriad number of submissions made in the conference, related to educational breakthroughs and sciences, amidst the recovery from the COVID-19 pandemic.
After review, 7 papers were selected. These papers were authored by researchers from Kazakhstan, Turkey, Iran, Cyprus, Slovenia, and Germany. The selected papers include the following: Scientific concept development in early childhood through the lens of “over-development”; The need for academic writing: An online in-service training for academicians; The impact of higher education students’ personality traits on susceptibility to specific gamification elements; Popularization of physical activity in rural schools of Kazakhstan's Aktobe region; Linked List Implementation “Online learning”; Comparison of BA and MA students' attitudes toward virtual education; Atelier experiences in interior architecture education: Zero waste approaches.
Dear reader, this issue would not have been possible without the massive input from our researchers, editorial board, and publishing team. We would therefore like to extend our gratitude to all who contributed to making this publication a success.
Dear reader, enjoy reading!!

Best Regards
Assoc. Prof. Dr. Jesus Garcia Laborda, University of Alcala, Spain
(Editor in chief)
EXTERNAL DACRIOCYSTORINOSTOMY WITH SILICONE TUBE INTUBATION; LONG TERM RESULTS
Authors: DOĞANAY Derya , ÖRNEK Firdevs , GÜVENÇ Umay 
Published: December 2022

Aim: To present the long-term results of bicanalicular silicone tube intubation combined with external dacryocystorhinostomy (EDRS) in-patient with nasolacrimal duct obstruction (NLDO)
Methods: Long-term results of 169 eyes of 169 patients who underwent external dacryocystorhinostomy between January 2010 and December 2020 in our clinic were evaluated, retrospectively. On the postoperative 1st day, 10th day, 1st month, 3rd month, 6th month, 9th month, 12th month, and last visits, the patients were evaluated. Especially on the postoperative 1st day for signs of infection, the position, tension, and placement of the silicone tube, and the presence of epiphora. Silicone tubes of the patients were removed 6 months after surgery. Surgical success; The disappearance of the patient's symptoms was evaluated as the lacrimal drainage open.
Results: 102 of our cases were female and 67 were male. The mean age-standard error was 55,48±1,36. Our average follow-up-standard error was 47,83±2,27 months. Surgical failure occurred in two of our patients. These cases were who were severe bleeding occurred during surgery and flaps were formed with difficulty. In these cases, revision surgeries were performed with an internal approach and surgical success were achieved in both of them. In our patients, who underwent bicanalicular silicone tube intubation surgery combined with external dacryocystorhinostomy, the surgical success rate was 98,76% in the first operation and 100% in the second operation.
Conclusions: Considering the long-term results of bicanalicular silicon tube intubation combined with dacryocystorhinostomy operations, it is the most effective surgical method with the highest success rate in nasolacrimal canal obstruction.
TRABALHO DA ENFERMAGEM E RISCOS DE DANOS À SAÚDE NA SALA DE RECUPERAÇÃO PÓS-ANESTÉSICA
Authors: Pagliarini Ana Maria , Rodrigues Luane Luz , Glanzner Cecília Helena 
Published: December 2022

O artigo tem por objetivo analisar o trabalho e os riscos de danos à saúde relacionados ao trabalho da equipe de Enfermagem da Sala de Recuperação Pós-Anestésica de um Hospital Universitário. Este é um estudo transversal com abordagem quantitativa realizado no período de novembro de 2017 a janeiro de 2018. A amostra foi composta por 28 trabalhadores de enfermagem que responderam a Escala de Organização Prescrita do Trabalho (EOPT) e a Escala de Avaliação dos Danos Relacionados ao Trabalho (EADRT). Os dados foram submetidos a análise estatística e a pesquisa foi aprovada pelo comitê de pesquisa da instituição. Na EOPT, identificou-se 53,6% dos trabalhadores apresentaram risco médio para risco psicossocial, enquanto que na EADRT, os danos psicológicos (82,1%) e danos sociais (85,7%) apresentaram risco baixo e os danos físicos (75%) apresentaram risco médio relacionados ao trabalho. O estudo permitiu concluir que o trabalho possui significância para além da esfera profissional do indivíduo na equipe de enfermagem estudada.
ARIMA MODEL IN PREDICTING OF COVID-19 EPIDEMIC FOR THE SOUTHERN AFRICA REGION
Authors: SHOKO Claris , NJUHO Peter 
Published: December 2022

Background: Coronavirus pandemic, a serious global public health threat, affects the Southern African countries more than any other country on the continent. The region has become the epicenter of the coronavirus with South Africa accounting for the most cases. To cap the deadly effect caused by the pandemic, we apply a statistical modelling approach to investigate and predict COVID-19 incidence. Methods: Using secondary data on the daily confirmed COVID-19 cases per million for Southern Africa Development Community (SADC) member states from March 5, 2020, to July 15, 2021, we model and forecast the spread of coronavirus in the region. We select the best ARIMA model based on the log-likelihood, AIC, and BIC of the fitted models. Results: The ARIMA (11,1,11) model for the complete data set was finally selected among ARIMA models based upon the parameter test and the Box–Ljung test. The ARIMA(11,1,9) was the best candidate for the training set. A 15-day forecast was also made from the model, which shows a perfect fit with the testing set. Conclusion: The number of new COVID-19 cases per million for the SADC shows a downward trend, but the trend is characterized by peaks from time to time. Tightening up of the preventive measures continuously needs to be adapted in order to eradicate the coronavirus epidemic from the population