bluuebunny/crossref_metadata_2025_split huggingface dataset:
Retrospective analysis of laboratory diagnostic data to assess the seasonal and proportional distribution of major tick-borne diseases in cattle from selected smallholder farms, Zambia
Authors: Silwamba Isaac , Chijikwa Jeremiah , Mutemwa Vigirio K. , Chanda James , Nkhata Augustine , Chapple Jenny , Sialyobo Misheck , Mutale Juliet , Zgambo Natasha , Chama Nicholas , Muyangana Lungowe , Phiri Philip , Munyeme Musso , Nalubamba King S. , Mainda Geoffrey , Muma John Bwalya 
Published: March 2023

Abstract
Tick-borne diseases (TBDs) are endemic in Zambia and several other Sub-Saharan countries. They affect livestock production by causing high morbidity and mortality, resulting in increased production losses in terms of live-weight gain, milk production, off-take rates, and draft power. Herein, we applied a facility-based design to assess the proportion and seasonal distribution of theileriosis, babesiosis, anaplasmosis, and heartwater in cattle from selected smallholder farms in Lusaka and Central provinces of Zambia using laboratory records for microscopic examination of haemoparasites. The overall proportions for theileriosis, babesiosis, and anaplasmosis were 33.7% (95% CI: 30.7–38.2%), 8.3% (95% CI: 6.4–10.9%), and 0.5% (95% CI: 0.1–1.4%), respectively. Heartwater was detected in all the six laboratory records reviewed. Lusaka province had the highest proportion of theileriosis at 30.2% (95% CI: 25.5–35.3%), followed by babesiosis, 8.5% (95% CI: 5.8–11.9%), and anaplasmosis, 0.3% (95% CI: 0.01–1.6%). Similarly, Central province had the highest proportion of theileriosis at 39.5% (95% CI: 33.8–45.4%), followed by babesiosis, 8.4% (95% CI: 5.5–12.2%), and anaplasmosis, 0.7% (95% CI: 0.1–2.5%). Among the districts, Rufunsa district had the highest proportion for theileriosis at 70.6% (95% CI: 44.0–89.7%), followed by Kafue, 54.5% (95% CI: 23.4–83.3%), and Shibuyunji, 51.4% (95% CI: 34.0–68.6%). Analysis of seasonal variation revealed no statistical difference between the dry and wet seasons for theileriosis, babesiosis, and anaplasmosis. Furthermore, there was no statistical difference between Central and Lusaka provinces for babesiosis and anaplasmosis except for theileriosis. These data may have implications on farmers’ herd health management strategies with respect to TBDs, and farmers should be sensitized for effective implementation of risk-based disease control.
Mitofusin 2 Sustains the Axonal Mitochondrial Network to Support Presynaptic Ca2+Homeostasis and the Synaptic Vesicle Cycle in Rat Hippocampal Axons
Authors: Vevea Jason D. , Chapman Edwin R. 
Published: March 2023

Mitochondria exert powerful control over cellular physiology, contributing to ion homeostasis, energy production, and metabolite biosynthesis. The trafficking and function of these organelles are particularly important in neurons, with impaired mitochondrial function or altered morphology observed in every neurodegenerative disorder studied. While mitochondrial biosynthetic products play a crucial role in maintaining cellular function, their resulting byproducts can have negative consequences. Thus, organelle quality control (QC) mechanisms that maintain mitochondrial function are imperative to restrict destructive signaling cascades in the cell. Axons are particularly sensitive to damage, and there is little consensus regarding the mechanisms that mediate mitochondrial QC in this compartment. Here, we first investigated the unstressed behavior of mitochondria in rat hippocampal neurons of mixed sex, focusing on mitochondrial trafficking and fusion to better understand potential QC mechanisms. We observed size and redox asymmetry of mitochondrial traffic in axons, suggesting an active QC mechanism in this compartment. We also document biochemical complementation upon the fusion and fission of axonal mitochondria. Eliminating fusion by knocking down the neuronal mitochondrial fusion protein mitofusin 2 (MFN2) reduced the rates of axonal mitochondrial trafficking and fusion, decreased the levels of synaptic vesicle (SV) proteins, inhibited exocytosis, and impaired SV recruitment from the reserve pool during extended stimulation. MFN2 knockdown also resulted in presynaptic Ca2+dyshomeostasis. Remarkably, upon MFN2 knockdown, presynaptic mitochondria sequestered Ca2+more efficiently, effectively limiting presynaptic Ca2+transients during stimulation. These results support an active mitochondrial trafficking and fusion-related QC process that supports presynaptic Ca2+handling and the SV cycle.SIGNIFICANCE STATEMENTDecreased or altered mitochondrial function is observed in many disease states. All neurodegenerative diseases co-present with some sort of mitochondrial abnormality. Therefore, identifying quality control mechanisms that sustain the mitochondrial network in neurons, and particularly in axons, is of significant interest. The response of axonal mitochondria to acutely applied toxins or injury has been studied in detail. Although informative, the response of neurons to these insults might not be physiologically relevant, so it is crucial to also study the basal behavior of axonal mitochondria. Here, we use fluorescent biosensors to investigate the mitochondrial network in neurons and examine the role of mitofusin 2 in maintaining the axonal mitochondrial network and in supporting the synaptic vesicle cycle.
Mujeres y videojuegos: ¿un mundo de trabajo en transformación?
Authors: González-Sancho Roy , Obando-Reyes Fernando 
Published: March 2023

This study analyzes the contrast between the conclusions provided by several international female academic productions and the life working experience communicated by four Costa Rican professional women in the development and analysis of videogames. The research encompasses the professional working conditions in the videogame industry for women. The investigation departs from a qualitative approach, with a descriptive scope. Furthermore, it uses the phenomenological method. The data analyzed comes from audiovisual productions and selected articles from countries in Latin America, Europe and the United States. It also includes 4 in-depth interviews with young professional women in the sector.
The results indicate that in spite of some advance in inclusive measurements for women and other social collectivities, there are still maintained conditions and practices which are affecting and limiting the professional development of women. Such practices can be found both in the so-called “first world” and in the Costa Rica´s emerging environment. Some possible guidelines are highlighted in order to revert this tendency.
Pemberitaan Media Online Terhadap Radikalisme di Garut Jawa Barat (Analisis Framing Detik.Com dan Okezone.Com)
Authors: Al-Hakim Lukman 
Published: March 2023

Framing sebuah institusi media massa dilihat berdasarkan fakta dan realitas yang terjadi di masyarakat. Beragam kasus dan peristiwa telah banyak diungkap secara objektif dan transparan tanpa pandang bulu. Seperti pada kasus pemberitaan gerakan radikalisme di Kabupaten Garut Jawa Barat yang dimuat di laman Detik.com dan Okezone.com edisi 4-5 Juli 2022. Tujuan dari penelitian ini adalah untuk mengetahui framing Detik.com dan Okezone.com terhadap gerakan radikalisme dengan metode kualitatif analisis framing model Robert M. Entman yang terdiri dari: pendefinisian masalah, diagnosa masalah, membuat keputusan moral, dan menekankan penyelesaian masalah, serta untuk mengetahui perbedaan framing isu radikalisme dari kedua media online tersebut. Hasil dari penelitian ini adalah: Pertama radikalisme merupakan paham yang mengandung unsur “kekerasan” dan “pembodohan” dalam memahami agama serta adanya upaya mendirikan Negara Islam Indonesia (NII). Kedua eksistensi gerakan radikalisme sebagai jalan pintas menuju surga tanpa ibadah dan hanya dengan biaya infak 25 ribu rupiah saja. Ketiga ditemukan fakta baru terdapat 41 dari 42 Kecamatan di Kabupaten Garut Jawa Barat menjadi korban radikalisme. Keempat upaya pemerintah atasi gerakan radikalisme yang masih terus membumi di Kabupaten Garut Jawa Barat. Serta terdapat perbedaan framing berita pada kedua media online tersebut, diantaranya: Detik.com cenderung memberitakan tentang gerakan mendirikan Negara Islam Indonesia (NII), sementara Okezone.com cenderung memberitakan tentang gerakan “pembodohan” umat dalam memahami agama.
Prevalencia de enfermedades no transmisibles y factores de riesgo en industria de Minas Gerais
Authors: Andrade Fabiana Martins Dias de , Machado Ísis Eloah , Barbosa Jaqueline Almeida Guimarães 
Published: March 2023

Objetivo: estimar a prevalência de doenças e agravos não transmissíveis e seus fatores de risco em industriários de Minas Gerais, Brasil.
Materiais e método: estudo transversal com dados secundários cedidos pelo Serviço Social da Indústria. As variáveis estudadas foram tabagismo, uso de álcool, inatividade física, alimentação inadequada, excesso de peso, doenças e agravos não transmissíveis referidos e autoavaliação da saúde. Calcularam-se as prevalências e as diferenças segundo sexo, faixa etária e escolaridade pelo teste x2 de Pearson. Na sequência, calcularam-se as razões de prevalência ajustadas pelas covariáveis por meio de regressão de Poisson.
Resultados: foram estudados 34.072 trabalhadores. A prevalência de prática insuficiente de atividade física foi 75 %, consumo inadequado de frutas 66 % e consumo regular de refrigerante ou suco artificial 42 %. O tabagismo foi relatado por 10 %, fumo passivo no ambiente de trabalho por 14 % e uso abusivo de álcool por 30 %. Dos trabalhadores, 55 % estavam acima do peso, 2 % referiram diabetes, 10 % hipertensão e 10 % colesterol elevado. Homens apresentaram maiores prevalências de alimentação inadequada e colesterol elevado.
Conclusões: os resultados mostram baixa prevalência de atividade física, alto consumo de alimentos não saudáveis e de sobrepeso, além de elevada prevalência de consumo abusivo de álcool entre trabalhadores das indústrias de Minas Gerais.
Impacto de la obsolescencia tecnológica programada en la gestión financiera personal
Authors: Guerra Herrera Nancy , Niño Beltrán Lady Carolina 
Published: March 2023

Objetivo: El propósito de la investigación es exponer el efecto de la obsolescencia tecnológica programada en la gestión financiera personal realizada mediante apps financieras de Android. Método: Se realizó un estudio cuantitativo con diseño exploratorio basándose en una muestra de 73 aplicaciones de la play store que gestionan las finanzas personales. Se emplearon las técnicas de observación no participante y análisis exploratorio de datos recopilando la información en registros de observación. Resultados y discusión: Se determinó que la gestión financiera personal mediada por apps financieras es afectada negativamente por la obsolescencia tecnológica y que el hardware y software de los smartphones materializan una tipología de obsolescencia que a su vez impacta a la etapa de control financiero. Se evidenció la inexistencia de estudios que relacionen directamente la obsolescencia tecnológica programada con la gestión financiera personal que utiliza apps, por lo que no se comprende la importancia de la continua adaptabilidad a las actualizaciones de hardware y software de los smartphones, alterando la toma de decisiones financieras. Conclusiones: Las finanzas personales gestionadas con apps financieras y/o smartphones son vulnerables ante la obsolescencia tecnológica, generando inseguridad en el manejo tecnológico de la información financiera ocasionando pérdida en su control financiero.
Fear and Coping with Death in Intensive Care Nurses: a Structural Model Predictor of Compassion Fatigue
Authors: Medina-Fernández Josué , Torres-Soto Nissa Yaing , Casco-Gallardo Karina , Ruiz-Lara Anahí , Martínez-Ramírez Beatriz , Fuentes-Fernández Esmeralda 
Published: March 2023

Objective. To determine the effect of fear and coping with death on compassion fatigue in nurses working in the intensive care unit.
Methods. Correlational-predictive design, applied in 245 nurses working in the intensive care unit through intentional sampling. The study applied a personal data card, the Collet-Lester Fear of Death Scale (α=0.72), the Bugen Fell of Death Scale (α=0.82), and the Empathy Exhaustion Scale (α=0.80). Descriptive and inferential statistics were performed, such as Spearman's test and a structural equation model.
Results. The work had 255 nurses who participated, finding a relationship among fear and coping toward death and compassion fatigue (p<0.01), together with the equation model showing that fear and coping toward death have a positive effect in 43.6% on compassion fatigue.
Conclusion. Fear and coping with death have an effect on compassion fatigue in nurses working in the intensive care unit, so that when working in a critical area it can cause health effects
Coseismic Surface Horizontal Deformation of the 2022 Mw 6.6 Menyuan, Qinghai, China, Earthquake from Optical Pixel Correlation of GF-7 Stereo Satellite Images
Authors: Han Nana , Zhang Guohong , Shan Xinjian , Zhang Yingfeng , Hetland Eric , Qu Chunyan , Gong Wenyu , Sun Guangtong , Li Chenglong , Fan Xiaoran , Huang Chuanchao 
Published: March 2023

AbstractQuantifying surface deformation due to earthquake-related surface rupturing is a critical research focus. Localized offsets on the primary fault can be obtained via field measurements of dislocated landforms. However, effectively quantifying distributed deformation, which can extend for tens to hundreds of meters around the fault zone, has only become possible with the development of remote sensing technology and optical pixel correlation techniques. In this study, we correlated pre- and post-earthquake GaoFen (GF)-2 and -7 images that were ortho-rectified by a digital elevation model generated from GF-7 stereo images to obtain surface horizontal deformation of the 2022 Mw 6.6 Menyuan earthquake. The surface rupture had a total length of 28 km along two segments separated by a stepover; in this study, we focused on the northern segment (23.5 km), which was distributed along the Lenglongling fault (LLLF). The total surface offset measured by our study had the maximum value of 4.0 m and a mean value of 1.9 m. The mean offset measured by field observations captured just 50% of the mean offset from optical pixel correlation. Overall, 57% of off-fault deformation (OFD) occurred on the LLLF, which is a mature fault, owing to soft near-surface materials. Comparison of the surface offset measured by pixel correlation data in our study and near ground slip from joint inversion of Interferometric Synthetic Aperture Radar and pixel correlation data suggests that OFD played a significant role in accommodating the shallow slip. The results of this study offer new insight into the characteristics of surface deformation.
Oral health related disorder among children with behavioral problems
Authors: Khatun Mst. Mahmuda , Shahid Shelina Fatema Binte , Gaffar Foyjunnesa , Uddin Md. Nizam 
Published: March 2023

Background: The best mouth function, the absence of disease, and oral health are achieved by maintaining the highest self-esteem possible. When someone has good dental health, they can communicate and connect with people without getting sick, feeling uncomfortable, or feeling embarrassed. This study aimed to evaluate the Oral health-related disorder specifically to assess dental caries and gingivitis among children with behavioral problems.
Methods: This study was a prospective cross-sectional investigation carried out at Kalachandpur Government Primary School and Jashim Uddin Institute, Dhaka. The study was carried out between October 2021 and December 2022 and included 650 pediatric patients who were aged between 6 to 15 years.
Results: Most 290 (44.62%) children were aged 6-9 years, 250 (38.46%) were 10-12 years, and the rest 110 (16.92%) were 13-15 years old. Patients with 11-15 years had lower dental caries. 310 (48%) were female, and 340 (52%) were male. Dental caries is associated with elevated risk. Children in the elevated caries risk group had a significantly higher mean value of conduct problems and Hyperactivity/inattention based on the SDQ compared to those with low caries risk. No statistically significant differences were found between the low caries risk group and the elevated caries group for the other subscales.
Conclusions: There were statistically more children in the study group who had a high risk of getting caries. Behavior problems were observed while externalizing children who had a high risk of getting caries. Children with externalizing behavior also have more conduct problems and hyperactivity compared to children with reduced caries risk.
Observational study of segmental epidural anesthesia for orthopedic surgeries
Authors: Badheka Jigisha , Dalvani Khatija , Singh Aditya , Gohil Yagnesh 
Published: March 2023

Background: Epidural anaesthesia is suitable technique for lower abdominal and lower limb surgery. Compared to conventional epidural anesthesia (EA), segmental epidural anaesthesia (SEA) denotes the use of a small volume enough to block only the segments involved in the field with stable hemodynamics and limited spread of analgesia. We decided to do study of SEA for lower limb surgeries. Aim was to observe characteristic of sensory and motor block, quality of analgesia, hemodynamics and peri-operative complications.
Methods: After institutional ethical committee approval, prospective observational study of SEA for orthopedic surgeries was carried out in 130 patients of 18 to 60 years of either sex with ASA grade І-Ш. For SEA, we used bolus dose of lignocaine with adrenaline (L+A) 2% 8 to 12 ml injected over 4 minutes according to anticipated segments required to be blocked and patient’s condition and type of surgery. Top up dosages were repeated every 60 minutes. Quality of analgesia and block, total local anesthetic used and hemodynamics were recorded intraoperatively. Results were analysed statistically and were compared using the student’s paired ‘t’ test. P value <0.05 was considered as significant.
Results: Requirement of bolus dose was 8 ml, 10 ml and 12 ml in 78 patients, 31 patients and 7 patients respectively. In all patients 1st top up dose was given while 2nd top up was required in 32 patients only. Intra op MAP remains near to baseline. Quality of block was excellent in 66 patients (55%), good in 35 patients (29%) and fair in 15 patients (12.5%).
Conclusions: We concluded that SEA is a safe and reliable technique for orthopedic surgeries with stable hemodynamics, limited spread of analgesia involving only required segments with minimal side effects.
Effectiveness of lockdown to mitigate the spread of COVID-19 pandemic during its first wave in India
Authors: Srinivas Vani 
Published: March 2023

Background: Countries across the globe had adopted various prevention and control measures ranging from social distancing and isolation, to shutting down of nonessential services and countrywide lockdowns. The objective of the study was to assess the effectiveness of the nation-wide lockdown to prevent or delay the spread of COVID-19 in India.
Methods: This was a cross sectional and descriptive study. We used the secondary data from WHO website, from 01 January to 30 October 2020. We calculated mean, median number of new cases, deaths reported per day and case fatality rate, using Microsoft excel spreadsheet.
Results: There was a steady rise in number of cases and deaths in India, during the lockdown and unlock period from phase-1 to phase-4. Approximately 10-fold increase in death was reported in the duration of 68 days of lockdown from phase-1 to Phase 4. The number of cases reported in unlock phase-4 were approximately 6 times more compared to unlock phase 1. The case fatality rate per day had declined during the lockdown period, from 3 .4% to 2 .5% deaths per day. The case fatality rate was lowest during the peak of pandemic, 1.27% in September 2020. Indicating good care of hospitalized patients compared to initial stage of pandemic in India.
Conclusions: Indian government had imposed complete sudden lockdown at the right time. The peak of pandemic was delayed or slowed down. Indicating the timing of lockdown is an essential step to save the lives in pandemic, in resource limited settings.
Management and visual outcome of neovascular glaucoma in diabetes mellitus patients
Authors: Nair Shamili S , Prashanth C N  
Published: March 2023

Aim of this study was to analyse the management of neovascular glaucoma (NVG) in patients with diabetes mellitus and assess the visual outcome. A retrospective case series was conducted. 20 diabetic patients with NVG who attended the retina clinic over a period of 1 year were taken for the study and were followed up for 6 months to 1 year. Among them, 15 patients had an effectively controlled intraocular pressure (IOP) after the treatment (16.68 ± 4.69 mmHg) as compared to the pre-treatment levels (42.59 ± 9.44, p&#60;0.05). There was improvement in visual acuity to a certain extent in 12 eyes (62.7%) whereas visual acuity in 4 (23.5%) eyes was noted to be ≥0.1, remained the same in 3 (17.6%) eyes, and became worse in 1 (5.8%) eye. Results showed that a comprehensive management with adequate number of pan-retinal photocoagulations (PRP), intravitreal/intracameral anti-vascular endothelial growth factor (VEGF) injections and early surgical interventions along with strict diabetic control can avert visual loss and improve the prognosis.
Visual outcome in suspected ocular tuberculosis and role of mantoux testing
Authors: Shreya  , Kumar H Mohan , Chidambara Lavanya 
Published: March 2023

To determine the role of mantoux test in treatment of ocular TB.Three patients who presented to the OPD with features of anterior Uveitis were examined completely, both systemically and ophthalmologically. BCVA, Color vision, Slit lamp examination, dilated fundus examination was done. Systemic investigations in pertaining to Uveitis was done(CBC, Mantoux, CXR, Serology, ESR).All patients systemically had all investigations negative (including Chest X-ray) except and strong Mantoux reaction with signs of active anterior Uveitis and Vitritis. In collaboration with the department of chest medicine, Anti tubercular treatment was commenced. Patients have recovered from the Uveitis and have improved symptomatically and clinically.Uveitis can be a presenting feature of extra pulmonary TB. Easily available and affordable Mantoux test can help in detecting TB and commencing treatment which can be sight saving. A close follow up for these patients is needed, as they have been started on ATT after testing mantoux strongly positive and should be closely monitored for any ocular toxicity due to ATT.
Genealogical Study on the Legitimacy Strategies in the Islamic Banking
Authors: Soediro Achmad , Kusumawardani Media , Farhan Muhammad 
Published: March 2023

This study aimed to explore legitimacy strategies in Islamic financial institutions andunderstand the process and reason for their shifting over time. A reflective approach was used towards literature data sources and a thematic analysis of interview results. Islamic Banking and financial institutions were seeking a legitimacy strategy by adopting sharia compliance to distinguish them from conventional banks. This study examined the development of Indonesia's Islamic banking and assessed responses from participants with an Islamic banking background. The results showed that the legitimacy strategy of Islamic banking changes over time. Initially, it used labeling, but the stakeholders' pressures and demands have led Islamic banking to change its strategy. It has moved through integrating financial and non-financial performance to a sharia compliance strategy. This study contributes to understanding Islamic banking's legitimacy strategy that has developed over time. Additionally, it helps develop a better legitimacy strategy in line with the future philosophical and ideological basis of Islamicbanking.