bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pregnancy- and lactation-associated osteoporosis: A report of six cases
Authors: Qian Ying , Wang Lei , Qu Wei , Zhai Kai , Wang Jingming , Wu Aifang , Huang Weimin 
Published: March 2023

Abstract
Objective To illustrate the clinical characteristics of pregnancy- and lactation-associated osteoporosis (PLO) by retrospectively analyzing six cases of PLO.
Methods Six cases of PLO diagnosed in our Endocrinology and Orthopedics Departments from January 2018 to June 2020 were retrospectively studied. The baseline characteristics, clinical features, laboratory findings, radiological manifestations and follow-up outcomes were analyzed and compared with previous reports.
Results The mean age of the six patients was 33.5 years old (range 30-36 years) with a mean height of 163 cm (range 151-171 cm), mean weight of 56.2 kg (range 47-73 kg) and mean body mass index (BMI) of 21.3 kg/m2 (range 17.4-28.5 kg/m2). All enrolled patients complained of low back pain, with a mean visual analogue scale (VAS) score of 7.0 points (4-10). The mean bone mineral density (BMD), as assessed by the Z-score obtained from the dual-energy X-ray absorptiometry measurement, was -2.90 (range -4.37- -1.34). All six patients underwent magnetic resonance imaging (MRI) scans and vertebral compressive fractures were detected in four patients. The main feature of MRI images of the patients was the appearance of strip-shaped abnormal signal area under the upper endplate of the vertebrae, with low T1 phase signal and high T2 fat-suppressed phase signal. The fractures mainly affected the thoracolumbar regions. Fractures in four patients were all multiple vertebral fractures, with at least two and at most nine vertebral fractures. All six patients received conservative treatment, and no surgical intervention. After a mean follow-up of 27.3 months (range 24-31 months), the symptoms of the six patients were significantly relieved, although four patients still had low back pain to varying degrees.
Conclusion PLO tends to occur in older and thinner women with clinical manifestations varying in severity. MRI often reveals multiple vertebral compressive fractures in patients with PLO. PLO has good prognosis with conservative treatment, but complete relief may take a long time.
The Paradox of Collective Climate Action in Rural U.S. Ecovillages: Ethnographic Reflections and Perspectives
Authors: Schelly Chelsea , Rubin Zach , Lockyer Joshua 
Published: March 2023

Abstract
Are ecovillages suited to the challenge of climate change and radical social transformation? While often framed as social experiments with the potential to support dramatic social change, we argue that ecovillages should be seen as more than that - complicated sites which both enable and constrain social action in the fight to stem the effects of climate change. As ethnographic researchers with a variety of experiences researching ecovillages, we critically examine some of the factors that affect the power of ecovillages to accomplish this mission, including: governance modes that support reduced individual consumption patterns and impact; a commons infrastructure with decreased socioeconomic demands on members, and differing geographic locales with varying socio-political limitations. We conclude this piece by discussing how these factors should inform future research on the transformative nature of ecovillages.
A Novel Mutation of the SOX10 Gene Associated with Waardenburg Syndrome Type IV
Authors: Wang Yanan , Chai Yuqiong , Zhang Pai , Zang Weiwei 
Published: March 2023

Abstract
Background
Waardenburg syndrome (WS) is a genetic disorder that affects skin, hair, and iris pigmentation, and causes sensorineural deafness. The syndrome is classified into four types (WS1, WS2, WS3, and WS4), each with different clinical phenotypes and underlying genetic causes. The aim of this study is to identify the pathogenic mutation in a Chinese family with Waardenburg syndrome type IV.
Methods
The patient and her parents underwent a comprehensive examination. DNA was extracted from their peripheral venous blood. The mutation was identified through whole exome sequencing technology and was validated via Sanger sequencing.
Results
The patient presents with iris pigmentary anomalies, congenital megacolon, and sensorineural hearing loss. And we identified a heterozygous c.452_456dup mutation in exon 3 of the SOX10 gene, which is known to be associated with Waardenburg syndrome type Ⅳ. Our analysis suggests that this mutation produces a truncated protein that may contribute to the development of the disease.
Conclusions
Our findings provide additional information for diagnosing clinical diseases associated with mutations in the SOX10 gene and expand the existing database of such mutations. The use of WES and Sanger sequencing can aid in the accurate diagnosis and management of WS and related syndromes.
Electric vehicle integration system for power management on a blockchain-based smart grid platform with AI capabilities
Authors: Khan Mohd. Afzal , Gupta Nidhi , Kathuria Rahit , Vanshika Sharma , Sharma Vivek , Vaghmare Anil Kumar 
Published: March 2023

Abstract
A virtual power plant (VPP) is composed of a network of dispersed power generating units, available power users, and storage systems. The AEBIS system is an AI-enabled, block chain-based electric car integration system that is presented in this research for power management in a smart grid platform. The use of AI based chips guarantees a performance that is economical. A safe and transparent service is further achieved with the addition of block chain technology to the system at an affordable memory and latency cost. A VPP is made up of a network of dispersed power generating units, users, and storage systems. During times of peak load, a VPP distributes the electricity generated by numerous connected units to balance the network's load. When used effectively, demand-side energy equipment like mobile robots and electric vehicles (EVs) may also balance the supply and demand of energy. The balancing of supply power is an ambitious goal due to the volatility in power produced by various power units. Furthermore, although it is crucial, the security of communications and the end installations has not received adequate attention. This article suggests an electrical solution that is blocking chain-based and AI-powered. The vehicle integration system for the energy management of the smart grid platform is known as AEBIS. The solution is based on artificial neural networks and federated learning algorithms for EV load prediction and utilizes the fleet of electric vehicles as both a consumer and a supplier of electric energy within a VPP platform. The evaluation findings demonstrate that the suggested approach produced high power consumption forecasts in the standard training scenario with an R2 score of 0.938. Applying a federated learning strategy resulted in a 1.7% accuracy reduction. The suggested system produces a dependable and prompt service to deliver additional electricity from the vehicular network as a result, consequently lowering the amount of power fluctuation and providing an accurate estimation of power consumption. Additionally, adopting an AI chip guarantees economical performance. A safe and transparent service may also be obtained at the level at the cost of an acceptable memory cost and latency thanks to the system's integration of block chain technology.
Infinite memory effects on the stabilization of a Biharmonic Schrödinger equation
Authors: Capistrano-Filho Roberto A. , de Jesus Isadora Maria , Martinez Victor Hugo Gonzalez 
Published: March 2023

Abstract
This paper deals with the stabilization of the linear Biharmonic Schrödinger equation in an $n$-dimensional open bounded domain under Dirichlet-Neumann boundary conditions considering three infinite memory terms as damping mechanisms. We show that depending on the smoothness of initial data and the arbitrary growth at infinity of the kernel function, this class of solution goes to zero with a polynomial decay rate like t-n depending on assumptions about the kernel function associated with the infinite memory terms.
2020 Mathematics Subject Classification. 35B40, 35B45.
"How I cook with no kitchen": An investigation of the public perception of #apartment kitchens on TikTok
Authors: Mandzufas Joelie , Lombardi Karen , Winter Dorian , Foster Sarah , Hickling Siobhan , Trapp Gina 
Published: March 2023

Abstract
Despite the prevalence of urban high density, little research to-date has investigated the impacts of apartment living on food practices. Physical constraints of apartment kitchens (size, storage, cooking facilities) and the influence of the surrounding community food environment may present challenges to apartment residents’ healthful food practices, particularly in smaller apartments. This study aimed to determine whether these hypothesised barriers were evident in TikTok videos (n=250) sampled from five popular apartment-related hashtags. Overall, the majority of videos (87%) portrayed apartment living with a positive or neutral sentiment; with only 2% of videos portraying kitchen size and function negatively. Only a small number of videos portrayed the food practices of cooking at home (n=11), grocery shopping (n=5), and eating foods prepared out of the home (n=5). Further research investigating the actual impact of apartment living on the food practices of residents will enable comparison of this public portrayal, to the reality.
Effect of breakdown path on discharge of Micro - gap electrode
Authors: Ma Guokai , Zhao Laijun , Wang Guoda , Zhang Hao , Sun Yanzhou 
Published: March 2023

Abstract
In order to study the causes and influencing factors of the "plateau period" of breakdown voltage curve at the micron scale, three groups of different electrodes were set up for gas discharge experiments within the range of 20-100 𝜇m electrode spacing and 1-100kPa air pressure, and the results were analyzed. Under the conditions of different electrode curvature radii, the breakdown voltage curve deviates from Paschen curve with the change of air pressure, and there is a "plateau period". The "plateau period" is the (Pd) min when the charged particles meet the minimum breakdown voltage by changing the path near the electrode edge, and the "plateau period" range is affected by the radius of curvature of the electrode edge. However, the breakdown voltage curve of the electrode edge after insulation treatment is consistent with the Paschen curve, and the breakdown path is not along the minimum spacing between the electrodes at the micron spacing.
The co-dispersal strategy of Endocarpon (Verrucariaceae) shapes an unusual lichen population structure
Authors: Yang ChunYan , Zhou QiMing , Shen Yue , Liu LuShan , Cao Yunshu , Tian HuiMin , Cao ShuNan , Liu Chuanpeng 
Published: March 2023

Abstract
Lichen as the typical symbioses, reproduction and dispersal strategies play a major role in shaping their population structure and photobiont diversity. Sexual reproduction strategy is common in lichenized fungi, which leads to a high lichen genetic diversity and a low photobiont selectivity. Whereas a rare myco-and photobiont co-dispersal sexual patterns in lichens whose mycobiont is sexually reproductive, provides a different insight to understand how lichen population structure is shaped. Individuals from Endocarpon (Verrucariaceae, Verrucariales, Ascomycota) are widely distributed in desert or high mountains with well-known stress tolerance, and implement a co-dispersal strategy that their ascospores are sprayed with photosynthetic algae. A total of 62 Endocarpon individuals and 12 related Verrucariaceae genera (Placidiopsis, Placidium, and Verrucaria) individuals, representing co-dispersal strategy and conventional independent dispersal mode were studied to explore the dispersal strategy impact on lichen population structures. These individuals were collected from six areas, spanning almost across China from north to south. Phylogenetic analysis revealed that Endocarpon, with a large-scale geographical distribution, showed an extremely high specificity of symbiotic associations with their photobiont, while the other genera showed different photobiont diversity. Furthermore, three types of group I intron at 1769 site have been found in most Endocarpon mycobionts, which showed a high variety of group I intron in the same insertion site even in the same species collected from one location. The current study suggested that the ascospore-alga co-dispersal mode of Endocarpon resulted in this unusual mycobiont-photobiont relationship; also provided an evidence for the horizontal transfer of group I intron that may suggest the origin of the complexity and diversity of lichen symbiotic associations.
Differential hypopigmentation between vitiligo and lichen sclerosus et atrophicus
Authors: Park Young Joon , Lee Heera , Park Hyung Soo , Kim You Chan 
Published: March 2023

Abstract
Several case studies of lichen sclerosus et atrophicus (LS) have reported its association with vitiligo. LS may result in oral and genital depigmentation without textural changes and should be differentiated from vitiligo. However, the histopathological features of hypopigmentation during vitiligo and LS have rarely been compared and have not been precisely described using quantitative immunohistochemical analysis. This study, therefore, aimed to investigate and compare the pigmentary characteristics of LS and vitiligo lesions using histochemical and immunohistochemical staining. We included 31 and 46 patients diagnosed with LS and vitiligo, respectively, at Ajou University Hospital between March 2009 and March 2020 in this study. Their medical charts and skin biopsy specimens were retrospectively reviewed. Additionally, Fontana–Masson staining for melanin and immunohistochemical staining for Melan-A, NKI/beteb, tyrosinase, and microphthalmia-associated transcription factor was performed. Melanin pigment was significantly increased in the epidermis of patients in the LS group compared with that in the vitiligo group. The number of melanocytes and their activity were also significantly increased in the LS group. However, 22.6% of LS tissues showed less melanin pigmentation, 25.8% of LS specimens exhibited a lower number of melanocytes, and 29.0% of LS specimens demonstrated less melanocyte activitythan the average number in vitiligo specimens. In conclusion, in our study, melanin pigmentation and the number of melanocytes decreased in several patients with LS, as in vitiligo patients. Therefore, to differentiate vitiligo from LS, both the clinical and histological findings must be comprehensively reviewed.
Exploration of new positions for cabozantinib for advanced hepatocellular carcinoma in the latest real-world practice
Authors: Kanzaki Hiroaki , Ogasawara Sadahisa , Okubo Tomomi , Itokawa Norio , Yoshino Ryohei , Fujimoto Kentaro , Kogure Tadayoshi , Yumita Sae , Ishino Takamasa , Ogawa Keita , Iwanaga Terunao , Nakagawa Miyuki , Fujiwara Kisako , Kojima Ryuta , Koroki Keisuke , Inoue Masanori , Kobayashi Kazufumi , Kanogawa Naoya , Kiyono Soichiro , Nakamura Masato , Kondo Takayuki , Nakagawa Ryo , Nakamoto Shingo , Muroyama Ryosuke , Chiba Tetsuhiro , Itobayashi Ei , Atsukawa Masanori , Kato Jun , Kato Naoya 
Published: March 2023

Abstract

Background:Cabozantinib was found to be effective as a second-line treatment after sorafenib in patients with advanced hepatocellular carcinoma (HCC) in phase 3 CELESTIAL trial. So far, as immunotherapy has substituted molecular target agents as the primary systemic therapy for advanced HCC, cabozantinib is extensively used in the latest real-world clinical practice in a greatly different position than that shown by the CELESTIAL trial. In the current analysis, we examined the safety and effectiveness of cabozantinib administration in real-life settings for patients with advanced HCC.Methods:We retrospectively obtained data from patients with advanced HCC who received cabozantinib in 3 institutions in Japan between September 14, 2018, and November 30, 2021.Results:During the study period, 23 patients with advanced HCC received cabozantinib. Our cohort included 21.7% of patients with Child-Pugh class B, and 52.2% of patients in fourth-line or later. The median progression-free survival of patients given cabozantinib was 3.7 months (95% confidence interval, 1.5–8.9 months). Regarding patients with Child-Pugh class B or administration in fourth-line or later, the discontinuation rate due to adverse events in patients who initialized at 40 mg or 20 mg was fewer, unlike those who initialized at 60 mg (42.9% vs. 75.0%,p= 0.205).Conclusion:In the era of immunotherapy, cabozantinib is extensively administered to patients with various advanced HCC, indicating that with precise dose reduction initiation, the clinical benefit might be achieved even in patients with poor liver function or at the late line.
Synthesis and characterization of an innovative poly vinyl alcohol / sodium alginate bioartificial hydrogel for forward-osmosis desalination
Authors: Saad M. A. , Sadik E. R. , Eldakiky B. M. , Moustafa H. M.A. , Fadl E. A. , He Z. , Elashtokhy EL. Z. , Khlifa R. E. , Zewail T. M. 
Published: March 2023

Abstract
Hydrogels are three-dimensional network of polymeric materials that can hold large amount of water due to their hydrophilic structure. Hydrogels have received considerable attention for their use in FO desalination. The primary goal of the present work is the synthesis of a bioartificial hydrogel from a blend of sodium alginate (SA) and polyvinyl alcohol (PVA) using epichlorohydrin (EPC) as cross-linking agent. The effects of the percentage of PVA in the blend and cross linker / total polymer ratio on equilibrium swelling ratio (ESR) were investigated to optimize the hydrogel’s composition. Furthermore, the water flux and the reverse solute flux of the optimum PVA/SA hydrogel was evaluated in batch FO unit under the effect of different parameters such as: hydrogel particle size, temperature of feed solution, feed solution concentration and membrane orientation. FTIR spectroscopy, SEM, XRD were used to characterize the prepared hydrogel. In addition, mechanical properties of the prepared hydrogel were measured. Results reveal that maximum % ESR of 5228 was achieved with a hydrogel which has 25% PVA and cross linker/total polymer ratio of 0.8. FO experimental data indicated that as the hydrogel particle size decreases the water flux increases. However, the increase of feed solution temperature has a proportional effect on water flux whereas the feed solution concentration has a reverse effect on water flux. PRO mode proves to be superior to FO mode. In all FO experiment reverse solute flux approached zero. The performance of the present hydrogel to desalinate real brackish water has been examined.
Exact Solutions of position dependent mass Schrodinger equation with Pseudoharmonic Oscillator and its thermal properties using extended Nikiforov-Uvarov method
Authors: Ikot Akpan , Okon I. B. , Okorie U. S. , Omugbe E. , Abdel-Aty A.-H. , Obagboye L. F. , Ahmadov A.I. , Okpara N , Duque C.A , Abdullah H , Qadir K 
Published: March 2023

Abstract
In this work, we find the exact solution of Schrödinger wave equation for position dependent mass with pseudoharmonic oscillator using extended Nikiforov-Uvarov method. We obtained the energy-eigen equation presented in a closed and compact form and used the result to study both superstatistics and thermodynamic properties by first determining the partition function of the system. The unnormalized wave function was obtained and expressed in terms of Confluent Heun function. Using the resulting energy eigen equation, the numerical computation were computed for varying masses for with fixed physical constant potential parameter λ. The numerical result shows that the bound state energies increase with quantum states but decreases with the dependent mass m(x). The thermodynamics and superstatistics plots are also reported.
Comparison of standard-percutaneous nephrolithotomy combined ultrasonic lithotripsy system and mini-percutaneous nephrolithotomy combined high-power holmium laser for staghorn calculus: A retrospective comparative study
Authors: Shen Zhonghua , Xie Linguo , Luo Di , Xie Haijie , Chen Hongyang , Liu Chunyu 
Published: March 2023

Abstract
Purpose To compare the outcomes of standard-percutaneous nephrolithotomy combined ultrasonic lithotripsy system(s-PCNL+ULS) and mini-percutaneous nephrolithotomy combined high-power holmium laser(m-PCNL+hHL) for the treatment of staghorn calculus.
Methods The data of patients who underwent PCNL for the treatment of staghorn calculus were retrospectively reviewed between 2019 and 2022 from the second hospital of Tianjin medical university. The nephrostomy tracts were dilatated to 24 F in standard PCNL and 16-18 F in mini PCNL, standard PCNL combined ultrasonic lithotripsy system and mini PCNL combined high-power holmium laser. The preoperative, intraoperative, and postoperative variables of the patients were calculated to evaluate the efficacy and reliability of the two groups.
Results 1778 patients were received PCNL between 2019 and 2022, After screening computed tomography, finaly 310 patients with staghorn calculus were included. 98 underwent s-PCNL+ULS and 212 underwent m-PCNL+hHL. The total operative time (min) ,haemoglobin deficit (ΔHGB (g/L)) ,the postoperative hospitalization days for s-PCNL+ULS and m-PCNL+hHL groups were 76.07±26.68 vs 103.93±24.84(P＜0.001), 9.30±9.26 VS 7.73±7.50(P=0.017); 7.32±5.14 VS 4.71±2.42(P＜0.001). The incidence complications for s-PCNL+ULS and m-PCNL+hHL groups were 28.57% vs 16.04%(P = 0.064), s-PCNL+ULS group had more severity complications (9.18% vs 2.83%, P = 0.022) . The firist and second stone-free rates of PCNL were 56.12% VS 57.08%(P=0.902) and 92.86% VS 86.32%(P=0.126) for the m-PCNL+hHL and s-PCNL+ULS groups.
Conclusion The efficacy of m-PCNL+hHL was comparable to s-PCNL+ULS in the treatment of staghorn calculus. The advantages of m-PCNL+hHL included the lower haemoglobin deficit, shorter hospital stay and lesser severity complications.
Enhancing Navigation Accuracy in Geostationary Orbit Through Utilization of Regional Navigation Satellite System
Authors: Nakajima Yu , Yamamoto Toru 
Published: March 2023

Abstract
This paper proposes the use of Regional Satellite Positioning Systems (RNSSs) in addition to a Global Navigation Satellite System (GNSS)to determine the positions of satellites in Geosynchronous EquatorialOrbit (GEO). Signals from GNSS satellites observed in GEO are limitedbecause they can only receive GPS signals over the other side of theearth where they are not obscured. In addition, those observable signalsare from a paricular direction opposite side of the earth, resulting inpoor Dilution of Precision (DOP), which causes a significant radial error.Signals from RNSSs, located at different altitudes from MEO GNSSs,are observed from the diverse direction compared to the MEO GNSSs.These additional signals from the diverse direction enhance observabilityand improve the DOP. In this paper, we analyze the link budget andDOP in GEO using GPS and Quasi-Zenith Satellite System (QZSS) asexamples to verify the effectiveness of receiving signals from near RNSSs.Our link budget analysis showed that QZSS signals could be receivedfrom satellites in GEO over a wide range. The DOP was improved byusing signals from a near QZSS. The proposed method can be utilizedfor other GEO RNSSs, such as NavIC or BeiDou, and can be expandedto any GEO satellite by adapting the receiver. In addition, the navigationperformance was analyzed to validate the improved performance.