bluuebunny/crossref_metadata_2025_split huggingface dataset:
Formation of hotel and restaurant services for rural green tourism enterprises
Authors: Marchenko Oksana , Postol Anatoly 
Published: February 2023

The subject of the research is the theoretical and practical aspects of the development of hotel and restaurant services of enterprises of rural green tourism. The purpose of the article is to substantiate the prospects for the development of hotel and restaurant services of rural green tourism enterprises, to determine their features and use in administration and management. The methodological basis of the article was both general scientific and special methods of scientific knowledge. The article used scientific research methods: historical, system-structural analysis and synthesis, monographic, statistical-economic, problem-targeted. Results of the article. It is noted that the implementation of functions, the provision of services by rural green tourism enterprises and their focus on the hotel and restaurant direction of business are based on the presence and use of significant tourism and recreation potential on the one hand and a relatively free market segment for small businesses in this area on the other. It is substantiated that rural green tourism is integrated into the general structure of tourist and hotel-restaurant activities and allows providing services even where it is not economically feasible to build separate hotels and restaurants. It was determined that the concentration of efforts of rural settlements and other small enterprises of rural green tourism mainly on hotel and restaurant services requires them to improve the quality of such services, to observe high sanitary and hygienic standards; security conditions; appropriate level of service; training of hosts and/or their employees in hospitality, tact, business communication; certain aesthetics and style of places of accommodation and food. Field of application of results. The results can be used by tourism enterprises, territorial communities, regional and state authorities, public organizations, individual entrepreneurs and activists, institutions of higher education, scientific institutions. Conclusions. Combined efforts are achieving changes for the better in the field of service, tourism, and the hotel and restaurant industry. And this, at the same time, is a significant contribution to the development of the village. An example can be the creation of local branches of the Association for the Development of Rural Green Tourism in the administrative regions of the country, associations of citizens interested in the development of infrastructure for rural green tourism, etc. Thus, we can assert the existence of a "multiplier effect" from rural tourism for both the hotel and restaurant business and for the formation of a special multifunctional model of the development of rural areas.
SISTEM INFORMASI MANAJEMEN PUBLIKASI ASIA PASIFIC JOURNAL OF MULTIDISCIPLINARY RESEARCH PADA LYCEUM OF THE PHILIPPINE UNIVERSITY
Authors: Tawaqqal Bagues Putra , Alamsyah Nur , Sidik Abdurrahman 
Published: February 2023

Asia Pacific Journal of Multidisciplinary Research terbuka untuk komunitas global cendekiawan yang bercita-cita agar penelitian mereka diterbitkan dalam akses terbuka dan jurnal cetak yang ditinjau sejawat. Kriteria utama untuk publikasi di Asia Pacific Journal of Multidisciplinary Research adalah signifikansi dari kontribusi sebuah artikel terhadap badan pengetahuan. Dalam proses penerimaan jurnal dari penulisan yang telah mendaftarkan diri masih menggunakan email dan penyimpanan dalam folder komputer. Sehingga beberapa masalah yang perlu dipecahkan yaitu pendataan anggota komunitas Asia Pasific Journal of Multidisciplinary Research dan arsip dari jurnal yang telah di publikasi. Hal ini kurang efektif dan efesien dalam penyimpanan data dan juga arsip, Sehingga memerlukan waktu dalam pemrosesan publikasi suatu jurnal. Sistem Informasi Manajemen Publikasi Jurnal ini dirancang dengan framework laravel dan MySQL sebagai penyimpanan data di basis data.Penelitian ini akan mengimplimentasikan framework laravel pada sistem informasi ini dan mempermuda pemrosesan publikasi jurnal dan pengolahan data jurnal dan anggota.
SISTEM INFORMASI MANAJEMEN DAN KEUANGAN BERBASIS WEB PADA KLINIK GIGI ELDENTAL BANJARMASIN
Authors: Mahdalena Mahdalena , Alamsyah Nur , Sidik Abdurrahman 
Published: February 2023

Klinik eldental merupakan klinik yang melayani dalam kesehatan gigi dan mulut. Selama ini pencatatan dalam pengolahan administrasi dan operasional klinik Eldental, seperti pengolahan data pasien, dokter, suster, obat, bahan perlengkapan, keuangan, pelaporan dan perawatan rekam medis pasien menggunakan cara manual dengan media buku besar dan kertas lebaran pasien dan sehingga menimbulkan kendala seperti memakan waktu yang lama saat pencarian data dan kehilangan data laporan.Dikarenakan dengan permasalahan ini maka dibuatkanlah sebuah aplikasi sistem informasi agar dapat mempermudah dalam meningkatkan kualitas pelayan klinik gigi Eldental. Penelitian ini dalam pengembangan sistem informasi menggunakan metode Waterfall, dibuat dengan menggunakan bahasa pemrograman PHP pada Laravel Framework, dan database MySQL.Hasil dari penelitian ini yaitu mempermudah dalam pengolahan data dokter, suster, pasien, obat, bahan, keuangan, pelaporan serta rekam medis pasien.
ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI APLIKASI PENCATATAN KEUANGAN
Authors: Andriani Juwita , Nur Arifah Amalina , Eka Setyaputri Khairina 
Published: February 2023

Financial management in a well-planned and well-planned way is very useful to help create more focused life goals, and make quick decisions. One of the causes of people's inefficiency in managing their finances is the high level of activity among the people, moreover managing finances manually takes too long to make decisions. Financial management is important for some people, considering that financial problems are a very sensitive issue for today's life, the culture among the people, especially in urban areas, is that the majority have a consumptive lifestyle. The importance of financial management is still a lot of people who are not aware of it, especially for personal financial management.
The population in this study were all users of financial recording applications (financial records). The samples in this study were students, lecturers, civil servants, BUMN employees, private employees and others who are in the Special Region of Yogyakarta. This study used a purposive sampling technique. The purposive sampling technique is a data collection technique with certain considerations or criteria, in this study the criteria are only users who use financial recording applications (financial records).
The results in this study are Self-efficacy has a positive effect on perceived ease of use, Perceived ease of use able to mediate Self-efficacy on intentions to use financial recording applications, Subjective norms have a positive effect on perceived usefulness, Perceived usefulness is able to mediate Subjective norms on intentions to use financial recording applications, Perception Ease of use has a positive effect on the intention to use the financial recording application, perceived usefulness has a positive effect on the intention to use the financial recording application.
Keyword: Self-efficacy, perceived ease of use, Subjective norm, perceived usefulness, intention to use the financial recording application.
Cognitive Trajectories and Associated Biomarkers in Patients with Mild Cognitive Impairment
Authors: Kim Bum Soo , Jun Sungmin , Kim Heeyoung ,   Disease Neuroimaging Initiative Alzheimer’s
Published: February 2023

Background: To diagnose mild cognitive impairment (MCI) patients at risk of progression to dementia is clinically important but challenging. Objective: We classified MCI patients based on cognitive trajectories and compared biomarkers among groups. Methods: This study analyzed amnestic MCI patients with at least three Clinical Dementia Rating (CDR) scores available over a minimum of 36 months from the Alzheimer’s Disease Neuroimaging Initiative database. Patients were classified based on their progression using trajectory modeling with the CDR-sum of box scores. We compared clinical and neuroimaging biomarkers across groups. Results: Of 569 eligible MCI patients (age 72.7±7.4 years, women n = 223), three trajectory groups were identified: stable (58.2%), slow decliners (24.6%), and fast decliners (17.2%). In the fifth year after diagnosis, the CDR-sum of box scores increased by 1.2, 5.4, and 11.8 points for the stable, slow, and fast decliners, respectively. Biomarkers associated with cognitive decline were amyloid-β 42, total tau, and phosphorylated tau protein in cerebrospinal fluid, hippocampal volume, cortical metabolism, and amount of cortical and subcortical amyloid deposits. Cortical metabolism and the amount of amyloid deposits were associated with the rate of cognitive decline. Conclusion: Data-driven trajectory analysis provides new insights into the various cognitive trajectories of MCI. Baseline brain metabolism, and the amount of cortical and subcortical amyloid burden can provide additional information on the rate of cognitive decline.
Can T1-Weighted Magnetic Resonance Imaging Significantly Improve Mini-Mental State Examination-Based Distinguishing Between Mild Cognitive Impairment and Early-Stage Alzheimer’s Disease?
Authors: Marcisz Anna ,   for the Alzheimer’s Disease Neuroimaging Initiative, Polanska Joanna 
Published: February 2023

Background: Detecting early-stage Alzheimer’s disease (AD) is still problematic in clinical practice. This work aimed to find T1-weighted MRI-based markers for AD and mild cognitive impairment (MCI) to improve the screening process. Objective: Our assumption was to build a screening model that would be accessible and easy to use for physicians in their daily clinical routine. Methods: The multinomial logistic regression was used to detect status: AD, MCI, and normal control (NC) combined with the Bayesian information criterion for model selection. Several T1-weighted MRI-based radiomic features were considered explanatory variables in the prediction model. Results: The best radiomic predictor was the relative brain volume. The proposed method confirmed its quality by achieving a balanced accuracy of 95.18%, AUC of 93.25%, NPV of 97.93%, and PPV of 90.48% for classifying AD versus NC for the European DTI Study on Dementia (EDSD). The comparison of the two models: with the MMSE score only as an independent variable and corrected for the relative brain value and age, shows that the addition of the T1-weighted MRI-based biomarker improves the quality of MCI detection (AUC: 67.04% versus 71.08%) while maintaining quality for AD (AUC: 93.35% versus 93.25%). Additionally, among MCI patients predicted as AD inconsistently with the original diagnosis, 60% from ADNI and 76.47% from EDSD were re-diagnosed as AD within a 48-month follow-up. It shows that our model can detect AD patients a few years earlier than a standard medical diagnosis. Conclusion: The created method is non-invasive, inexpensive, clinically accessible, and efficiently supports AD/MCI screening.
Background Music and Memory in Mild Cognitive Impairment: The Role of Interindividual Differences
Authors: Calabria Marco , Ciongoli Francesco , Grunden Nicholas , Ordás Celia , García-Sánchez Carmen 
Published: February 2023

Background: Recent research has shown that background music may improve memory consolidation and retrieval. Nevertheless, in the clinical conditions preceding dementia such as mild cognitive impairment (MCI), there is no current evidence speaking to what effect background music during memory tasks has on impaired cognition. Objective: Across three experiments, we investigated if background music is able to improve memory performance, the most impacted cognitive domain in amnestic MCI. Methods: We tested the effect of background music by using a face recognition memory task in patients with amnestic MCI. In Experiment 1, we tested the effect of background music on memory when it was played solely during an encoding phase. In Experiment 2, we explored effects of background music when played during both encoding and recognition phases. In Experiment 3, we explored the role of musically induced arousal on memory. Results: The main finding from these three experiments was that background music played during a memory task did not improve or worsen participant performance. However, when exposed to high-arousal music, memory performance was predicted by individual mood regulation. For low-arousal music conditions, there was a negative relationship between rating scores for music pleasantness and performance on the memory task. Conclusion: Our results suggest that the benefits of background music on memory in individuals with MCI are modulated by interindividual preferences towards music.
Theory and Practice of Forensic Science and Criminalistics: War Challenges
Authors: Kliuiev Oleksandr 
Published: February 2023

Зараз ви маєте нагоду ознайомитися із 27-м випуском збірника наукових праць «Теорія та практика судової експертизи і криміналістики». Це вже другий номер, який редакція видає під час російської війни проти України. Співзасновники видання — Національний науковий центр «Інститут судових експертиз ім. Засл. проф. М. С. Бокаріуса» і Національний юридичний університет імені Ярослава Мудрого — упродовж 22 років дотримуються періодичності наукового видання, і навіть війна не здатна завадити цій благородній справі.
Gastric emptying performance of stomach-partitioning gastrojejunostomy versus conventional gastrojejunostomy for treating gastric outlet obstruction: A retrospective clinical and numerical simulation study
Authors: Zhang Haiqiao , Xu Fengyan , Zheng Zhi , Liu Xiaoye , Yin Jie , Fan Zhenmin , Zhang Jun 
Published: February 2023

Purpose: This study evaluated the gastric emptying performance of stomach-partitioning gastrojejunostomy (SPGJ) versus conventional gastrojejunostomy (CGJ) for treating gastric outlet obstruction (GOO).Methods: First, 73 patients who underwent SPGJ (n = 48) or CGJ (n = 25) were involved. Surgical outcomes, postoperative recovery of gastrointestinal function, delayed gastric emptying, and nutritional status of both groups were compared. Second, a three-dimensional stomach model was constructed based on the gastric filling CT images from a GOO patient with a standard stature. The present study evaluated SPGJ numerically by comparing it with CGJ in terms of local flow parameters such as flow velocity, pressure, particle retention time, and particle retention velocity.Results: Clinical data found that SPGJ had significant advantages over CGJ in terms of time to pass gas (3 versus 4 days, p &lt; 0.001), time to oral intake (3 versus 4 days, p = 0.001), postoperative hospitalization (7 versus 9 days, p &lt; 0.001), the incidence of delay gastric emptying (DGE) (2.1% versus 36%, p &lt; 0.001), DGE grading (p &lt; 0.001), and complications (p &lt; 0.001) for GOO patients. Moreover, numerical simulation revealed that the SPGJ model would induce contents in stomach discharge to the anastomosis at a higher speed, and only 5% of that flowed to the pylorus. SPGJ model also had a low-pressure drop as the flow from the lower esophagus to the jejunum, reducing the resistance to food discharge. Besides, the average retention time of particles in the CGJ model is 1.5 times longer than that in the SPGJ models, and the average instantaneous velocity in CGJ and SPGJ models are 22 mm/s and 29 mm/s, respectively.Conclusion: Compared with CGJ, patients after SPGJ had better gastric emptying performance and better postoperative clinical efficacy. Therefore, we think that SPGJ may be a better option for treating GOO.
Aerobic and facultative anaerobic Klebsiella pneumoniae strains establish mutual competition and jointly promote Musca domestica development
Authors: Zhang Kexin , Wang Shumin , Yao Dawei , Zhang Xinyu , Zhang Qian , Liu Wenjuan , Li Ying , Yin Yansong , An Sha , Zhang Ruiling , Zhang Zhong 
Published: February 2023

IntroductionThe gut microenvironment in housefly harbors a rich and diverse microbial community which plays a crucial role in larval development. However, little is known about the impact of specific symbiotic bacteria on larval development as well as the composition of the indigenous gut microbiota of housefly.MethodsIn the present study, two novel strains were isolated from housefly larval gut, i.e., Klebsiella pneumoniae KX (aerobe) and K. pneumoniae KY (facultative anaerobe). Moreover, the bacteriophages KXP/KYP specific for strains KX and KY were used to analyse the effects of K. pneumoniae on larval development.ResultsOur results showed that dietary supplementation with K. pneumoniae KX and KY individually promoted housefly larval growth. However, no significant synergistic effect was observed when the two bacterial strains were administered in combination. In addition, using high-throughput sequencing, it was demonstrated that the abundance of Klebsiella increased whereas that of Provincia, Serratia and Morganella decreased when housefly larvae received supplementation with K. pneumoniae KX, KY or the KX-KY mixture. Moreover, when used combined, K. pneumoniae KX/KY inhibited the growth of Pseudomonas and Providencia. When the abundance of both bacterial strains simultaneously increased, a balance in total bacterial abundance was reached.DiscussionThus, it can be assumed that strains K. pneumoniae KX and KY maintain an equilibrium to facilitate their development in housefly gut, by establishing competition but also cooperation with each other to maintain the constant composition of gut bacteria in housefly larvae. Thus, our findings highlight the essential role of K. pneumoniae in regulating the composition of the gut microbiota in insects.
Donation type and the effect of pre-transplant donor specific antibodies – Data from the Swiss Transplant Cohort Study
Authors: de Rougemont Olivier , Deng Yun , Frischknecht Lukas , Wehmeier Caroline , Villard Jean , Ferrari-Lacraz Sylvie , Golshayan Déla , Gannagé Monique , Binet Isabelle , Wirthmueller Urs , Sidler Daniel , Schachtner Thomas , Schaub Stefan , Nilsson Jakob ,   the Swiss Transplant Cohort Study
Published: February 2023

IntroductionThe type of donation may affect how susceptible a donor kidney is to injury from pre-existing alloimmunity. Many centers are, therefore, reluctant to perform donor specific antibody (DSA) positive transplantations in the setting of donation after circulatory death (DCD). There are, however, no large studies comparing the impact of pre-transplant DSA stratified on donation type in a cohort with a complete virtual cross-match and long-term follow-up of transplant outcome.MethodsWe investigated the effect of pre-transplant DSA on the risk of rejection, graft loss, and the rate of eGFR decline in 1282 donation after brain death (DBD) transplants and compared it to 130 (DCD) and 803 living donor (LD) transplants.ResultsThere was a significant worse outcome associated with pre-transplant DSA in all of the studied donation types. DSA directed against Class II HLA antigens as well as a high cumulative mean fluorescent intensity (MFI) of the detected DSA showed the strongest association with worse transplant outcome. We could not detect a significant additive negative effect of DSA in DCD transplantations in our cohort. Conversely, DSA positive DCD transplants appeared to have a slightly better outcome, possibly in part due to the lower mean fluorescent intensity (MFI) of the pre-transplant DSA. Indeed when DCD transplants were compared to DBD transplants with similar MFI (&lt;6.5k), graft survival was not significantly different.DiscussionOur results suggest that the negative impact of pre-transplant DSA on graft outcome could be similar between all donation types. This suggests that immunological risk assessment could be performed in a similar way regardless of the type of donor kidney transplantation.
Bioregionalization in a data-poor situation: Mapping of Uruguayan marine benthic regions
Authors: Limongi Pablo , Ortega Leonardo , Horta Sebastián , Burone Leticia , Carranza Alvar 
Published: February 2023

IntroductionThe Uruguayan Exclusive Economic Zone (U-EEZ) is still lacking a technically sound and institutionally agreed system for classifying marine benthic ecosystems. This fact, added to the growing anthropic pressure marine ecosystems face in the U-EEZ, increases the vulnerability of these ecosystems and their associated biodiversity. Despite this, there is valuable and abundant disaggregated environmental and biological information for benthic systems.MethodsIn this work, we used ca. 4000 records of all major Phyla of benthic invertebrates to determine discrete benthic regions for the U-EEZ. We looked at the structuring forces of bathymetry, salinity, and water masses. First, we categorized the multivariate structure according to statistical significance to test a priori categories for univariate descriptors. Then, we mapped unique combinations of categories of structuring variables, which largely determine the structure and composition of benthic communities. Operationally, the variables to be analyzed were classified, and subsequently, group (cluster) and SIMPROF analyzes were performed.ResultsThe results suggest seven bathymetric categories, two of water masses and two of salinity, significantly structuring the benthic communities. The combination of these categories suggests nine discrete benthic marine regions for the U-EEZ, with heterogeneous structural characteristics. Our results provide an initial model of distinct benthic ecological complexes in U-EEZ.DiscussionHowever, caution should be exerted when using this model during decision-making. For example, implementing use restrictions of benthic areas should rely on further groundtruthing, including direct seafloor observations and collections. The latter is relevant since our system is based on the analysis of accumulated historical data that may or may not represent the current condition of habitats of interest.
Characteristics and result reporting of registered COVID-19 clinical trials of Chinese and Indian traditional medicine: A comparative analysis
Authors: Zhao Nan , Pandey Kritika , Lakshmanan Skanthesh , Zhao Ran , Fan Jingchun , Zhang Junhua , Bachmann Max O. , Fan Hong , Song Fujian 
Published: February 2023

ObjectiveTo assess the main characteristics and result reporting of registered COVID-19 interventional trials of traditional Chinese medicine and traditional Indian medicine.Materials and methodsWe assessed design quality and result reporting of COVID-19 trials of traditional Chinese medicine (TCM) and traditional Indian medicine (TIM) registered before 10 February 2021, respectively, on Chinese Clinical Trial Registry (ChiCTR) and Clinical Trial Registry-India (CTRI). Comparison groups included registered COVID-19 trials of conventional medicine conducted in China (WMC), India (WMI), and in other countries (WMO). Cox regression analysis was used to assess the association between time from trial onset to result reporting and trial characteristics.ResultsThe proportion of COVID-19 trials investigating traditional medicine was 33.7% (130/386) among trials registered on ChiCTR, and 58.6% (266/454) on CTRI. Planned sample sizes were mostly small in all COVID-19 trials (median 100, IQR: 50–200). The proportion of trials that were randomized was 75.4 and 64.8%, respectively, for the TCM and TIM trials. Blinding measures were used in 6.2% of the TCM trials, and 23.6% of the TIM trials. Cox regression analysis revealed that planned COVID-19 clinical trials of traditional medicine were less likely to have results reported than trials of conventional medicine (hazard ratio 0.713, 95% confidence interval: 0.541–0.939; p = 0.0162).ConclusionThere were considerable between-country and within-country differences in design quality, target sample size, trial participants, and reporting of trial results. Registered COVID-19 clinical trials of traditional medicine were less likely to report results than trials of conventional medicine.