bluuebunny/crossref_metadata_2025_split huggingface dataset:
An approach for assessing and ranking fisheries management scenarios in spatially delimited marine areas
Authors: Clare D S , Martinez R , Goodsir F , Spence M A , Tyllianakis E , Ware S , Schratzberger M 
Published: April 2023

Abstract
Spatial restrictions to human activities such as bottom trawling are increasingly used to improve the ecological condition of disturbed habitats. Such management interventions typically have socio-economic consequences, which creates a challenge for those making decisions about which activities should be restricted and where restrictions should apply. We present an approach for predicting the effects of fisheries management scenarios in spatially delimited marine areas and ranking them—using a loss function—according to how well they achieve desired outcomes across a set of ecological and socio-economic indicators. This approach is demonstrated by simulating alternative fishing gear restrictions and zoning options within a hypothetical marine protected area (MPA). Relative benthic status (RBS; an indicator of ecological condition) and relative catch value (RCV; an indicator of potential economic cost) were estimated for the baseline environment and 21 potential management scenarios. The rank order depended on which indicator was prioritized (i.e. whether RBS or RCV was given greater weighting in the loss function), with the top-ranked scenarios in each case involving considerably different management measures. The methods presented can be applied anywhere using locally or strategically relevant indicators to help identify spatial fisheries management measures that minimize ecological and socio-economic trade-offs.
Bronchiolitis, Regardless of Its Etiology and Severity, Is Associated With Increased Risk of Asthma: A Population-Based Study
Authors: Muñoz-Quiles Cintia , López-Lacort Mónica , Díez-Domingo Javier , Orrico-Sánchez Alejandro 
Published: April 2023

Abstract
An association exists between severe respiratory syncytial virus (RSV)–bronchiolitis and a subsequent increased risk of recurrent wheezing (RW) and asthma. However, a causal relationship remains unproven. Using a retrospective population-based cohort study (339 814 children), bronchiolitis during the first 2 years of life (regardless of etiology and severity) was associated with at least a 3-fold increased risk of RW/asthma at 2–4 years and an increased prevalence of asthma at ≥5 years of age. The risk was similar in children with mild bronchiolitis as in those with hospitalized RSV-bronchiolitis and was higher in children with hospitalized non-RSV-bronchiolitis. The rate of RW/asthma was higher when bronchiolitis occurred after the first 6 months of life. Our results seem to support the hypothesis of a shared predisposition to bronchiolitis (irrespective of etiology) and RW/asthma. However, 60% of hospitalized bronchiolitis cases in our setting are due to RSV, which should be paramount in decision-making on imminent RSV prevention strategies.
A lizard is never late: Squamate genomics as a recent catalyst for understanding sex chromosome and microchromosome evolution
Authors: Pinto Brendan J , Gamble Tony , Smith Chase H , Wilson Melissa A 
Published: April 2023

Abstract
In 2011, the first high-quality genome assembly of a squamate reptile (lizard or snake) was published for the green anole. Dozens of genome assemblies were subsequently published over the next decade, yet these assemblies were largely inadequate for answering fundamental questions regarding genome evolution in squamates due to their lack of contiguity or annotation. As the “genomics age” was beginning to hit its stride in many organismal study systems, progress in squamates was largely stagnant following the publication of the green anole genome. In fact, zero high-quality (chromosome-level) squamate genomes were published between the years 2012 and 2017. However, since 2018, an exponential increase in high-quality genome assemblies has materialized with 24 additional high-quality genomes published for species across the squamate tree of life. As the field of squamate genomics is rapidly evolving, we provide a systematic review from an evolutionary genomics perspective. We collated a near-complete list of publicly available squamate genome assemblies from more than half-a-dozen international and third-party repositories and systematically evaluated them with regard to their overall quality, phylogenetic breadth, and usefulness for continuing to provide accurate and efficient insights into genome evolution across squamate reptiles. This review both highlights and catalogs the currently available genomic resources in squamates and their ability to address broader questions in vertebrates, specifically sex chromosome and microchromosome evolution, while addressing why squamates may have received less historical focus and has caused their progress in genomics to lag behind peer taxa.
Longitudinal canonical correlation analysis
Authors: Lee Seonjoo , Choi Jongwoo , Fang Zhiqian , Bowman F DuBois 
Published: April 2023

AbstractThis paper considers canonical correlation analysis for two longitudinal variables that are possibly sampled at different time resolutions with irregular grids. We modelled trajectories of the multivariate variables using random effects and found the most correlated sets of linear combinations in the latent space. Our numerical simulations showed that the longitudinal canonical correlation analysis (LCCA) effectively recovers underlying correlation patterns between two high-dimensional longitudinal data sets. We applied the proposed LCCA to data from the Alzheimer’s Disease Neuroimaging Initiative and identified the longitudinal profiles of morphological brain changes and amyloid cumulation.
A leaf-level spectral library to support high-throughput plant phenotyping: predictive accuracy and model transfer
Authors: Wijewardane Nuwan K , Zhang Huichun , Yang Jinliang , Schnable James C , Schachtman Daniel P , Ge Yufeng 
Published: April 2023

Abstract
Leaf-level hyperspectral reflectance has become an effective tool for high-throughput phenotyping of plant leaf traits due to its rapid, low-cost, multi-sensing, and non-destructive nature. However, collecting samples for model calibration can still be expensive, and models show poor transferability among different datasets. This study had three specific objectives: first, to assemble a large library of leaf hyperspectral data (n=2460) from maize and sorghum; second, to evaluate two machine-learning approaches to estimate nine leaf properties (chlorophyll, thickness, water content, nitrogen, phosphorus, potassium, calcium, magnesium, and sulfur); and third, to investigate the usefulness of this spectral library for predicting external datasets (n=445) including soybean and camelina using extra-weighted spiking. Internal cross-validation showed satisfactory performance of the spectral library to estimate all nine traits (mean R2=0.688), with partial least-squares regression outperforming deep neural network models. Models calibrated solely using the spectral library showed degraded performance on external datasets (mean R2=0.159 for camelina, 0.337 for soybean). Models improved significantly when a small portion of external samples (n=20) was added to the library via extra-weighted spiking (mean R2=0.574 for camelina, 0.536 for soybean). The leaf-level spectral library greatly benefits plant physiological and biochemical phenotyping, whilst extra-weight spiking improves model transferability and extends its utility.
The Cm14-3-3μ protein and CCT transcription factor CmNRRa delay flowering in chrysanthemum
Authors: Cheng Hua , Zhang Jiaxin , Zhang Yu , Si Chaona , Wang Juanjuan , Gao Zheng , Cao Peipei , Cheng Peilei , He Yuehui , Chen Sumei , Chen Fadi , Jiang Jiafu 
Published: April 2023

Abstract
The floral transition from vegetative to reproductive growth is pivotal in the plant life cycle. NUTRITION RESPONSE AND ROOT GROWTH (OsNRRa), as a CONSTANS, CONSTANS-LIKE, TOC1 (CCT) domain protein, delays flowering in rice, and an orthologous protein, CmNRRa, inhibits flowering in chrysanthemum; however, the underlying mechanism remains unknown. In this study, using yeast two-hybrid screening, we identified the 14-3-3 protein family member Cm14-3-3µ as a CmNRRa-interacting protein. A combination of bimolecular fluorescence complementation, pull-down, and co-immunoprecipitation assays was performed to confirm the physical interaction between CmNRRa and Cm14-3-3µ. In addition, expression analysis showed that CmNRRa but not Cm14-3-3µ responded to the diurnal rhythm, whereas both genes were highly expressed in leaves. Moreover, the function of Cm14-3-3µ in flowering time regulation was similar to that of CmNRRa. Furthermore, CmNRRa repressed chrysanthemum FLOWERING LOCUS T-like 3 (CmFTL3) and an APETALA 1 (AP1)/FRUITFULL (FUL)-like gene (CmAFL1) but induced TERMINAL FLOWER1 (CmTFL1) directly by binding to their promoters. Cm14-3-3µ enhanced the ability of CmNRRa to regulate the expression of these genes. These findings suggest that there is a synergistic relationship between CmNRRa and Cm14-3-3µ in flowering repression in chrysanthemum.
Spectroscopy of QUBRICS quasar candidates: 1672 new redshifts and a golden sample for the Sandage test of the redshift drift
Authors: Cristiani Stefano , Porru Matteo , Guarneri Francesco , Calderone Giorgio , Boutsia Konstantina , Grazian Andrea , Cupani Guido , D’Odorico Valentina , Fontanot Fabio , Martins Carlos J A P , Marques Catarina M J , Maitra Soumak , Trost Andrea 
Published: April 2023

ABSTRACT
The QUBRICS (QUasars as BRIght beacons for Cosmology in the Southern hemisphere) survey aims at constructing a sample of the brightest quasars with $z \lower.5ex\hbox{$\,\, \buildrel\gt \over \sim \,\,$}2.5$, observable with facilities in the Southern Hemisphere. QUBRICS makes use of the available optical and IR wide-field surveys in the South and of Machine Learning techniques to produce thousands of bright quasar candidates of which only a few hundred have been confirmed with follow-up spectroscopy. Taking advantage of the recent Gaia Data Release 3, which contains 220 million low-resolution spectra, and of a newly developed spectral energy distribution fitting technique, designed to combine the photometric information with the Gaia spectroscopy, it has been possible to measure 1672 new secure redshifts of QUBRICS candidates, with a typical uncertainty of σz = 0.02. This significant progress of QUBRICS brings it closer to (one of) its primary goals: providing a sample of bright quasars at redshift 2.5 &lt; z &lt; 5 to perform the Sandage test of the cosmological redshift drift. A Golden Sample of seven quasars is presented that makes it possible to carry out this experiment in about 1500 h of observation in 25 yr, using the ANDES spectrograph at the 39m ELT, a significant improvement with respect to previous estimates.
A simple sub-grid model for cosmic ray effects on galactic scales
Authors: Hopkins Philip F , Butsky Iryna S , Ji Suoqing , Kereš Dušan 
Published: April 2023

ABSTRACT
Many recent numerical studies have argued that cosmic rays (CRs) from supernovae (SNe) or active galactic nuclei (AGNs) could play a crucial role in galaxy formation, in particular by establishing a CR-pressure-dominated circumgalactic medium (CGM). But explicit CR-magnetohydrodynamics (CR-MHD) remains computationally expensive, and it is not clear whether those results can be applied to simulations that do not explicitly treat magnetic fields or resolved interstellar medium phase structure. We therefore present an intentionally extremely simplified ‘sub-grid’ model for CRs, which attempts to capture the key qualitative behaviors of greatest interest for those interested in simulations or semi-analytical models including some approximate CR effects on galactic (≳ kpc) scales, while imposing negligible computational overhead. The model is numerically akin to some recently developed sub-grid models for radiative feedback, and allows for a simple constant parametrization of the CR diffusivity and/or streaming speed; it allows for an arbitrary distribution of sources (proportional to black hole accretion rates or star–particle SNe rates or gas/galaxy star formation rates), and interpolates between the limits where CRs escape the galaxies with negligible losses and those where CRs lose most of their energy catastrophically before escape (relevant in e.g. starburst galaxies). The numerical equations are solved trivially alongside gravity in most codes. We compare this to explicit CR-MHD simulations and discuss where the (many) sub-grid approximations break down, and what drives the major sources of uncertainty.
A Quality Improvement Pilot Project for Noise Reduction in the NICU
Authors: Hull William , Wright Karen 
Published: April 2023

Background:
Increased noxious noise leads to adverse short-term and long-term effects on the growing neonate. The American Academy of Pediatrics recommends maintaining a noise level of less than 45 decibels (dBA). The average baseline noise level in an open-pod neonatal intensive care unit (NICU) was 62.6 dBA.

Purpose:
The purpose of this pilot project was to reduce the average noise levels by 39% at the end of an 11-week period.

Methods:
The location of the project was in a large, high-acuity level IV open-pod layout NICU that consisted of 4 pods, one of which was cardiac-focused. The average baseline noise level in the cardiac pod was 62.6 dBA in a 24-hour period. Noise levels were not monitored before this pilot project. This project was implemented over an 11-week period. Several modes of education were used for parents and staff. Post-education, Quiet Times were implemented at set times twice daily. Noise levels were monitored for 4 weeks during Quiet Times, with weekly noise level updates for staff. General noise levels were collected a final time to evaluate the overall change in the average noise levels.

Results:
At the end of the project, noise levels decreased from 62.6 dBA to 54 dBA, a 13.7% reduction.

Implications for Practice and Research:
At the end of this pilot project it was noted that: Online modules were the best way to educate staff. Parents should be included in the implementation of quality improvement. Healthcare providers need to know and understand that they can make preventative changes to improve the outcomes of the population.
Relationships Between the Auditory Nerve’s Ability to Recover From Neural Adaptation, Cortical Encoding of and Perceptual Sensitivity to Within-channel Temporal Gaps in Postlingually Deafened Adult Cochlear Implant Users
Authors: He Shuman , Yuan Yi , Skidmore Jeffrey 
Published: April 2023

Objective:
As a step toward identifying the origin of the across-electrode variation in within-channel gap detection thresholds (GDTs) measured in individual cochlear implant (CI) users, this study assessed the relationships between the auditory nerve’s (AN’s) ability to recover from neural adaptation, cortical encoding of and perceptual sensitivity to within-channel temporal gaps in postlingually deafened adult CI users.

Design:
Study participants included 11 postlingually deafened adults with Cochlear Nucleus devices, including three bilaterally implanted participants. In each of the 14 ears tested, recovery from neural adaptation of the AN was measured using electrophysiological measures of the electrically evoked compound action potential at up to four electrode locations. The two CI electrodes in each ear showing the largest difference in the speed of adaptation recovery were selected for assessing within-channel temporal GDT. GDTs were measured using both psychophysical and electrophysiological procedures. Psychophysical GDTs were evaluated using a three-alternative, forced-choice procedure, targeting 79.4% correct on the psychometric function. Electrophysiological GDTs were measured using the electrically evoked auditory event-related potential (eERP) evoked by temporal gaps embedded in electrical pulse trains (i.e., the gap-eERP). Objective GDT was defined as the shortest temporal gap that could evoke a gap-eERP. Related-samples Wilcoxon Signed Rank test was used to compare psychophysical GDTs and objective GDTs measured at all CI electrode locations. It was also used to compare psychophysical GDTs and objective GDTs measured at the two CI electrode locations with different speeds or amounts of adaptation recovery of the AN. A Kendall Rank correlation test was used to assess the correlation between GDTs measured at the same CI electrode location using psychophysical or electrophysiological procedures.

Results:
Objective GDTs were significantly larger than those measured using psychophysical procedures. There was a significant correlation between objective and psychophysical GDTs. GDTs could not be predicted based on the amount or the speed of adaptation recovery of the AN.

Conclusions:
Electrophysiological measures of the eERP evoked by temporal gaps can potentially be used to assess within-channel GDT in CI users who cannot provide reliable behavioral responses. The difference in adaptation recovery of the AN is not the primary factor accounting for the across-electrode variation in GDT in individual CI users.
What Happens After a Vertebral Body Tether Break? Incidence, Location, and Progression With Five-year Follow-up
Authors: Yang Michael J. , Samdani Amer F. , Pahys Joshua M. , Quinonez Alejandro , McGarry Maureen , Grewal Harsh , Hwang Steven W. 
Published: April 2023

Study Design.
Retrospective review.

Objective.
To study risk factors for anterior vertebral body tether (VBT) breakage.

Summary of Background Data.
VBT is used to treat adolescent idiopathic scoliosis in skeletally immature patients. However, tethers break in up to 48% of cases.

Materials and Methods.
We reviewed 63 patients who underwent thoracic and/or lumbar VBT with a minimum five-year follow-up. We radiographically characterized suspected tether breaks as a change in interscrew angle >5°. Demographic, radiographic, and clinical risk factors for presumed VBT breaks were evaluated.

Results.
In confirmed VBT breaks, the average interscrew angle change was 8.1°, and segmental coronal curve change was 13.6°, with a high correlation (r=0.82). Our presumed VBT break cohort constituted 50 thoracic tethers, four lumbar tethers, and nine combined thoracic/lumbar tethers; the average age was 12.1±1.2 years and the mean follow-up was 73.1±11.7 months. Of 59 patients with thoracic VBTs, 12 patients (20.3%) had a total of 18 breaks. Eleven thoracic breaks (61.1%) occurred between two and five years postoperatively, and 15 (83.3%) occurred below the curve apex (P<0.05). The timing of thoracic VBT breakage moderately correlated with more distal breaks (r=0.35). Of 13 patients who underwent lumbar VBT, eight patients (61.5%) had a total of 12 presumed breaks. Six lumbar breaks (50%) occurred between one and two years postoperatively, and seven (58.3%) occurred at or distal to the apex. Age, sex, body mass index, Risser score, and curve flexibility were not associated with VBT breaks, but the association between percent curve correction and thoracic VBT breakage trended toward significance (P=0.054). Lumbar VBTs were more likely to break than thoracic VBTs (P=0.016). Seven of the patients with presumed VBT breaks (35%) underwent revision surgery.

Conclusions.
Lumbar VBTs broke with greater frequency than thoracic VBTs, and VBT breaks typically occurred at levels distal to the curve apex. Only 15% of all patients required revision.

Level of Evidence.
3.
Distal Phalanx Intraosseous Epidermoid Cyst
Authors: AlMarshad Felwa A. , Mahabbat Nehal A. , Alzahrani Abdullah M. , Shash Hayam Ali , Al-Qattan Mohammad M. , Jarman Abdulaziz T. 
Published: April 2023

Summary:
An intraosseous epidermal cyst is a benign cystic lesion that occurs in the bones. It is assumed to be caused by congenital causes or trauma, and because the cyst forms in the soft tissue surrounding the bone, it can lead to bone loss. Intraosseous epidermal cysts have a well-defined radiolucent lesion with cortical extension on radiography. Due to clinical and radiological signs being similar, it is vital to distinguish an intraosseous epidermal cyst from other diseases that develop at the distal phalanx. A rare example of intraosseous epidermal cysts at the distal phalanx is reported. We describe the clinical, radiological, and pathologic aspect of this lesion, as well as our current therapeutic strategy.
An Algorithm in Managing Deep Inferior Epigastric Vessel Interruption in Free Flap Breast Reconstruction
Authors: Kapila Ayush K. , Kempny Tomas , Knoz Martin , Holoubek Jakub , Lipovy Bretislav , Hamdi Moustapha 
Published: April 2023

Background:
Previous surgical procedures in the abdomen are no longer contra-indications for free flap breast reconstruction using the deep inferior epigastric artery perforator flap. Nonetheless, a possible consequence of previous surgical procedures may be trauma to the deep inferior epigastric (DIE) pedicle, leading to interruption. In these cases, a modification in operative strategy may be required.

Methods:
A study was performed across two centers, during a 10-year period between January 1, 2010 and December 2019. Patient and outcome data were collected from the patient file and operation notes.

Results:
Four cases with clear evidence of DIE pedicle interruption were found, with an average age of 54 years and an average body mass index of 28.9. Three patients had a preoperative diagnosis of DIE pedicle interruption on CT angiography, whereas in one case this was found peroperatively. For three cases, unilateral reconstruction was performed, and for one, bilateral reconstruction. Four flaps (in three cases) were unipedicled; the contralateral DIE pedicle was used in three, and the superficial system was used in one. For the bipedicled case, two hemiflaps were used, with the interrupted DIE pedicle anastomosed to a branch of the contralateral DIE pedicle.

Conclusions:
Interrupted DIE vessels remain a challenge for free flap breast reconstruction. The four cases demonstrated in this article highlight different surgical strategies, with an emphasis on detailed preoperative planning, including CT angiography. We present an algorithm to aid the reader in approaching cases with an interrupted DIE pedicle.
Management of the Fontan patient during pregnancy
Authors: Gupta Tripti , Thompson Jennifer , Lindley Kathryn J. 
Published: April 2023

Purpose of review
Patients with single-ventricle Fontan palliation surgery often wish to pursue pregnancy. Pregnancies should be planned with well tolerated and effective contraception, and preconception risk stratification by adult congenital heart disease and maternal foetal medicine specialists.

Recent findings
Although infertility and foetal complications, including pregnancy loss, preterm birth and foetal growth restriction, are common, most patients with Fontan palliations can successfully complete pregnancy with a team-based approach. Important risk predictors are resting oxygen saturations, baseline functional status and the presence of systemic complications of the Fontan repair, including advanced Fontan associated liver disease, plastic bronchitis and ventricular dysfunction. Common maternal cardiovascular complications include arrhythmia, heart failure and thromboembolism. Delivery planning with input from an obstetric anaesthesiologist who has knowledge of complex congenital heart defects can facilitate appropriate, individualized monitoring and pain control. A vaginal delivery with consideration of an assisted second stage is appropriate for most single ventricle patients, in the absence of obstetric or foetal indications for caesarean delivery. Close postpartum monitoring and follow up is recommended, as the early postpartum period is the highest risk time for cardiovascular complications in patients with congenital heart disease.

Summary
A multidisciplinary approach to managing pregnancy and delivery in patients with Fontan circulation facilitates optimal maternal and infant outcomes.