bluuebunny/crossref_metadata_2025_split huggingface dataset:
Declarative Memory Through the Lens of Single-Trial Peaks in High-Frequency Power
Authors: Dede Adam J.O. , Cross Zachariah R. , Gray Samantha M. , Kelly Joseph P. , Yin Qin , Vahidi Parisa , Asano Eishi , Schuele Stephan U. , Rosenow Joshua M. , Wu Joyce Y. , Lam Sandi K. , Raskin Jeffrey S. , Lin Jack J. , McManus Olivia Kim , Sattar Shifteh , Shaikhouni Ammar , King-Stephens David , Weber Peter B. , Laxer Kenneth D. , Brunner Peter , Roland Jarod L. , Saez Ignacio , Girgis Fady , Knight Robert T. , Ofen Noa , Johnson Elizabeth L. 
Published: January 2025

SummaryDeclarative memory depends on the coordination of local processing, indexed by high-frequency broadband (HFB) activity, with global network organization, indexed by theta oscillations. However, theta and HFB exhibit asynchronous timing, raising the question of how results of local processing are communicated throughout the network. Using intracranial EEG in patients performing a recognition memory task, we examined this coordination across the medial temporal lobe (MTL) and prefrontal cortex (PFC). HFB peak activity was earlier in the MTL than PFC. Anchoring analyses of theta phase clustering and connectivity to HFB peaks revealed strong phase clustering locked to HFB peaks in the PFC, as well as connectivity between the PFC and MTL that predicted individual memory performance. Graph analysis revealed specific connections amidst sparse network connectivity during memory success. This study demonstrates that transient brain states linked to internal physiological events support memory and refines our understanding of local and network-level process interactions.HighlightsMemory-linked theta activity is time-locked to internal brain eventsNetwork connectivity changes dynamically during memory processingSparse network connectivity supports successful memorySpecific sequences of transient states may be critical for declarative memory
Estimating the clinical and economic burden of medically attended influenza in South Korea, stratified by age and comorbidity: A five-season hospital-based surveillance data, 2014/15-2018/19
Authors: Choi Min Joo , Choi Won Suk , Song Joon Young , Cheong Hee Jin , Noh Ji Yun , Wie Seong-Heon , Lee Jin Soo , Lee Jacob , Kim Hyo Youl , Kim Shin-Woo , Park Kyong-Hwa , Kim Woo Joo 
Published: January 2025

AbstractObjectivesTo estimate the nationwide clinical and economic burden of influenza across five seasons (2014/15–2018/19) in South Korea, stratified by age and comorbidity, using data from the Hospital-based Influenza Morbidity & Mortality (HIMM) surveillance network.MethodsData were collected from eight university hospitals, including adults (≥20 years) with laboratory-confirmed influenza. The catchment population was calculated using hospital and national statistical data. Economic costs were evaluated from a societal perspective.ResultsDuring the study period, the incidence per 100,000 persons of medically attended influenza occurrence ranged from 113.1 to 220.7, with hospitalization at 35.5 to 76.8, intensive care unit admission at 4.2 to 9.2, and deaths at 1.4 to 3.6 among the adult population. The total socioeconomic costs ranged from $156 to $316 million annually, primarily due to indirect costs associated with early death, peaking during the 2017/18 season, which had the largest outbreak scale, particularly among older adults. In contrast, the per capita average costs, ranging from $2,747 to $4,072, were highest in the 2018/19 season, followed by the 2015/16 season. For at-risk individuals, the per capita average socioeconomic costs were 1.5–2.3 times higher than that of the general adult population.ConclusionsInfluenza poses a substantial economic burden in South Korea. Additional strategies are needed to alleviate morbidity and mortality in older adults and to protect at-risk individuals who are not currently covered by the National Immunization Program.
Sexual dimorphism in human muscle ageing
Authors: Fieldsend Thomas W. , O’Neill Callum R. , Shrivastava Akshita , Ogden Helen E. , Dand Nick , Hughes Simon M. 
Published: January 2025

AbstractSex differences in human muscle strength, size, and quality are well characterised, but their alteration with age is less clear. Here we report a novel and striking sexual dimorphism in arm muscle ageing in 478,438 UK Biobank participants aged 40–82 yr. While there was a modest sex difference in age-related strength decline, muscle mass loss was considerably more pronounced in males, both in absolute and percentage terms. We also introduce a novel measure of muscle quality, which showed substantially greater age-related decline in females. These trends held across independent analyses of separate cross-sectional and longitudinal participant groups, and persisted after accounting for systematic size differences between the sexes. Furthermore, sex differences were apparent irrespective of female menopause status or HRT usage history. Defining sarcopenia on the basis of muscle mass is therefore inappropriate, particularly for females. Our findings demonstrate that sex-specific criteria based on muscle function, not mass, should be used to diagnose sarcopenia, and prompt consideration of sex-specific interventions.
The Future of HIV: Challenges in meeting the 2030Ending the HIV Epidemic in the U.S. (EHE)reduction goal
Authors: Bleichrodt Amanda M , Okano Justin T , Fung Isaac Ch , Chowell Gerardo , Blower Sally 
Published: January 2025

AbstractObjective(s)To predict the burden of HIV in the United States (US) nationally and by region, transmission type, and race/ethnicity through 2030.MethodsUsing publicly available data from the CDC NCHHSTPAtlasPlusdashboard, we generated 11-year prospective forecasts of incident HIV diagnoses nationally and by region (South, non-South), race/ethnicity (White, Hispanic/Latino, Black/African American), and transmission type (Injection-Drug Use, Male-to-Male Sexual Contact (MMSC), and Heterosexual Contact (HSC)). We employed weighted (W) and unweighted (UW)n-sub-epidemic ensemble models, calibrated using 12 years of historical data (2008-2019), and forecasted trends for 2020-2030. We compared results to identify persistent, concerning trends across models.ResultsWe projected substantial decreases in incident HIV diagnoses nationally (W: 27.9%, UW: 21.9%), and in the South (W:18.0%, UW: 9.2%) and non-South (W: 21.2%, UW: 19.5%) from 2019 to 2030. However, concerning non-decreasing trends were observed nationally in key sub-populations during this period: Hispanic/Latino persons (W: 1.4%, UW: 2.6%), Hispanic/Latino MMSC (W: 9.0%, UW: 9.9%), people who inject drugs (PWID) (W: 25.6%, UW: 9.2%), and White PWID (W: 3.5%, UW: 44.9%). The rising trends among Hispanic/Latino MMSC and overall PWID were consistent across the South and non-South regions.ConclusionsAlthough the forecasted national-level decrease in the number of incident HIV diagnoses is encouraging, the US is unlikely to achieve theEnding the HIV Epidemic in the U.S.goal of a 90% reduction in HIV incidence by 2030. Additionally, the observed increases among specific subpopulations highlight the importance of a targeted and equitable approach to effectively combat HIV in the US.
What adults in rural South Asia eat and when they eat it: evidence from Bangladesh, India, and Nepal
Authors: Scott Samuel , Patwardhan Sharvari , Ruel Marie , Chakrabarti Suman , Neupane Sumanta , Manohar Swetha , Moursi Mourad , Menon Purnima 
Published: January 2025

ABSTRACTBackgroundPoor diets pose a threat to all forms of malnutrition and diet-related noncommunicable diseases (NCDs). Data on dietary patterns are scarce in South Asia.ObjectivesWe sought to describe overall diet quality, intake of foods and food groups, and eating occasions among adults in rural South Asia.MethodsData were from five districts across Bangladesh (n=2,802 individuals), India (n=1,672), and Nepal (n=1,451). The Global Diet Quality Score (GDQS) application was used to measure intake of foods on the previous day, with each food tagged to an eating occasion. Diet quality and the risk of diet-related noncommunicable diseases (NCDs) were described using GDQS total (0–49), GDQS positive (0–32) and GDQS negative (0–17) metrics for overall, healthy, and unhealthy food intake respectively.ResultsDiet quality was low, with similar scores across countries for GDQS total (17-19 depending on country), GDQS positive (7–8) and GDQS negative (10–12), indicating low intake of healthy foods as the main contributor to poor diets. Over 90% of adults had levels of GQDS scores associated with moderate/high risk for diet-related NCDs, with the proportion at high risk in Bangladesh being 2-3x higher than other countries. Across sites, intake of refined grains (white rice), sweets (sugar, biscuits), and white tubers (potatoes) was common. One-third of adults did not eat breakfast in Nepal, and snacking was twice as common in males (63%) versus females (33%) in Bangladesh.ConclusionsThese findings highlight the need to improve diets in rural South Asia and may help inform interventions targeting food intake patterns.
Vertical transmission of core endophytes through the seeds
Authors: Sanz-Puente Irene , Redondo-Salvo Santiago , Torres-Cortés Gloria , de Toro María , Fernandes Susana , Börner Andreas , Lorenzo Óscar , de la Cruz Fernando , Robledo Marta 
Published: January 2025

AbstractPlant-associated microorganisms, particularly endophytes, are essential for plant health and development. Endophytic microbiota is intimately associated with host plants colonizing various tissues, including seeds. Seed endophytes are particularly noteworthy because of their potential for vertical transmission. This pathway may play a role in the long-term establishment and evolution of stable bacteria-host interactions across plant generations. Hundreds of seed-bacteria associations have been recently uncovered; however, most seem to be transient or unspecific. While it is known that microorganisms can be transmitted from plant tissues to seeds and from seeds to seedlings, the experimental confirmation of bacterial transfer through successive plant generations remains unreported. In this study, we identifiedPantoeaas the unique core endophytic bacteria inhabiting the endosperms of 24 wheat seed samples originally harvested in different worldwide locations. Remarkably,Pantoeais the genus with the highest relative average abundance in wheat seeds (61%) and also in germinated seedlings grown under gnotobiotic conditions (30%). In the field, it was the only genus dwelling roots, shoots, spikes and seeds of 4 different wheat varieties tested and its abundance progressively increased across these tissues. This genuine pattern of vertical enrichment, which was not found in other common wheat-associated taxa, suggests a role in the transfer of these endophytic bacteria through the seeds. To confirm intergenerational transmission, parental plants were inoculated with labelledPantoeaisolates, which specifically colonized the next generations of Poaceae plants, experimentally demonstrating bacterial vertical inheritance to the offspring generations and suggesting transmission specificity.
The Chimeric Peptide (GEP44) Reduces Body Weight and Both Energy Intake and Energy Expenditure in Diet-Induced Obese Rats
Authors: Goldberg Matvey , Blevins James E. , Wolden-Hanson Tami , Elfers Clinton T. , Chichura Kylie S. , Ashlaw Emily F. , den Hartigh Laura J. , Roth Christian L. , Doyle Robert P. 
Published: January 2025

AbstractWe recently reported that a chimeric peptide (GEP44) targeting the glucagon-like peptide-1 receptor (GLP-1R) and neuropeptide Y1- and Y2-receptors decreased body weight (BW), energy intake and core temperature in diet-induced obese (DIO) male and female mice. In the current study, we tested the hypothesis that the strong reduction of body weight in response to GEP44 is partially related to the stimulation of energy expenditure (EE). To test this, rats were maintained on a HFD for at least 4 months to elicit DIO prior to undergoing a sequential 2-day vehicle period, 2-day GEP44 (50 nmol/kg) period and a minimum 2-day washout period and detailed measures of energy homeostasis. GEP44 (50 nmol/kg) reduced EE (indirect calorimetry), respiratory exchange ratio (RER), core temperature, activity, energy intake and BW in male and female rats. As in our previous study in mice, GEP44 reduced BW in male and female HFD-fed rats by 3.8 ± 0.2% and 2.3 ± 0.4%, respectively. These effects appear to be mediated by increased lipid oxidation and reductions of energy intake as GEP44 reduced RER and cumulative energy intake in male and female HFD-fed rats. The strong reduction of body weight in response to GEP44 is related to a robust reduction of energy intake, but not to stimulation of EE. The paradoxical finding that GEP44 reduced EE might be secondary to a reduction of diet-induced thermogenesis or might indicate an important mechanism to limit the overall efficacy of GEP44 to prevent further weight loss.
Dynamic Transcriptomic Remodeling in Human Neural Progenitor Cells Reveals Mechanisms for Vision Preservation in Retinitis Pigmentosa Model
Authors: Shahin Saba , Bell Shaughn , Lu Bin , Banerjee Somanshu , Swarup Vivek , Xu Hui , Chetsawang Jason , Ramirez Stephany , Alfaro Jorge S , Laperle Alexander , Svendsen Soshana , Svendsen Clive N. , Wang Shaomei 
Published: January 2025

SUMMARYHuman neural progenitor cells (hNPCs) have shown promise in slowing down retinal degeneration in animal models and are currently being tested in clinical trials for treating retinitis pigmentosa (RP). However, the status of grafted hNPCs and their interaction with host retinal cells over time is largely unknown. Here, we investigated single-cell transcriptomic changes in grafted hNPCs and host retinal cells following injection into a rodent model for RP. Grafted hNPCs and host retinal cells undergo dynamic transcriptomic changes in the degenerative retinal environment. Grafted hNPCs protect vision through multiple mechanisms, including trophic factor support, modulation of metabolic activity, reduction of apoptosis, oxidative stress, and inflammation, alongside extracellular matrix remodeling. CellChat analysis revealed a progressive decline in intercellular signaling and communication strength between hNPCs and host retinal cells over time. This study indicates that enhancing trophic factor supports and improving host retinal environment are key targets to enable long-term vision preservation.
Necrotizing enterocolitis causes increased ileal goblet cell loss inWnt2bKO mice
Authors: Adegboye Comfort , Emeonye Chidera , Wu Yu-Syuan , Kwon Jaedeok , Oliveira Luiz Fernando Silva , Raveeniraraj Sathuwarman , O’Connell Amy E. 
Published: January 2025

AbstractWNT2B is Wnt ligand which is able to support intestinal stem cells (ISC) in culture and support the intestinal epithelium in vivo. We have previously shown that WNT2B is critical for resistance to colitis, but not small intestinal injury, in the adult mouse. WNT2B is thought to coordinate with WNT3 in supporting ISC, and we have also shown that WNT3 expression is low in the early postnatal ileum in mice. Here, we hypothesized that WNT2B may be more critical in the small intestine during early development, and we challengedWnt2bKO mice and controls with experimental necrotizing enterocolitis (NEC) on postnatal days 5-8.Wnt2bKO mice had similar ileum histology and injury scores to control mice. Molecular analyses showed thatWnt2bKO mice have differences inLgr5andTlr4expression compared to wild type controls in untreated conditions, but under experimental NEC expression of epithelial markers and inflammatory genes associated with NEC were similar to wild type. Periodic acid Schiff positive cells were lower in the villi ofWnt2bKO mice during NEC, however expression of goblet cell markers was not different compared to wild type mice. We also used an organoid-based NEC model to highlight the epithelium in isolation and also found no impact of WNT2B KO in the setting of NEC. These data further affirm that WNT2B is critical for inflammation responses in the mouse colon, but does not appear to play a major role in the small intestine, no matter the developmental period.
Neural encoding of biomechanically (im)possible human movements in occipitotemporal cortex
Authors: Marrazzo Giuseppe , De Martino Federico , Mukovskiy Albert , Giese Martin A. , de Gelder Beatrice 
Published: January 2025

AbstractUnderstanding how the human brain processes body movements is essential for clarifying the mechanisms underlying social cognition and interaction. This study investigates the encoding of biomechanically possible and impossible body movements in occipitotemporal cortex using ultra-high field 7Tesla fMRI. By predicting the response of single voxels to impossible/possible movements using a computational modelling approach, our findings demonstrate that a combination of postural, biomechanical, and categorical features significantly predicts neural responses in the ventral visual cortex, particularly within the extrastriate body area (EBA), underscoring the brain’s sensitivity to biomechanical plausibility. Lastly, these findings highlight the functional heterogeneity of EBA, with specific regions (middle/superior occipital gyri) focusing on detailed biomechanical features and anterior regions (lateral occipital sulcus and inferior temporal gyrus) integrating more abstract, categorical information.
Imaging ferroelectric domains with soft-x-ray ptychography at the oxygen K-edge
Authors: Butcher Tim A. , Phillips Nicholas W. , Wei Chia-Chun , Chang Shih-Chao , Beinik Igor , Thånell Karina , Yang Jan-Chi , Huang Shih-Wen , Raabe Jörg , Finizio Simone 
Published: January 2025

The ferroelectric domain structure of a freestanding BiFeO3 film was visualized by ptychographic dichroic imaging with linearly polarized x-rays at the O K-edge around 530 eV. The dichroic contrast is maximized at the energy of the hybridization of the O 2p state and the Fe 3d orbitals, which is split by the octahedral crystal field of the perovskite structure. The microscopy images thus obtained complement the ptychographic imaging of the antiferromagnetic contribution at the Fe L3-edge. The approach can be extended to the separation of different ferroic contributions in other multiferroic oxides.

Published by the American Physical Society
2025
Hadronic cross section measurements with the DAMPE space mission using 20 GeV-10 TeV cosmic-ray protons and
He4
Authors: Alemanno F. , An Q. , Azzarello P. , Barbato F. C. T. , Bernardini P. , Bi X. J. , Cagnoli I. , Cai M. S. , Casilli E. , Catanzani E. , Chang J. , Chen D. Y. , Chen J. L. , Chen Z. F. , Coppin P. , Cui M. Y. , Cui T. S. , Cui Y. X. , Dai H. T. , De Benedittis A. , De Mitri I. , de Palma F. , Di Giovanni A. , Ding Q. , Dong T. K. , Dong Z. X. , Donvito G. , Droz D. , Duan J. L. , Duan K. K. , Fan R. R. , Fan Y. Z. , Fang F. , Fang K. , Feng C. Q. , Feng L. , Frieden J. M. , Fusco P. , Gao M. , Gargano F. , Gong K. , Gong Y. Z. , Guo D. Y. , Guo J. H. , Han S. X. , Hu Y. M. , Huang G. S. , Huang X. Y. , Huang Y. Y. , Ionica M. , Jiang L. Y. , Jiang Y. Z. , Jiang W. , Kong J. , Kotenko A. , Kyratzis D. , Lei S. J. , Li W. H. , Li W. L. , Li X. , Li X. Q. , Liang Y. M. , Liu C. M. , Liu H. , Liu J. , Liu S. B. , Liu Y. , Loparco F. , Luo C. N. , Ma M. , Ma P. X. , Ma T. , Ma X. Y. , Marsella G. , Mazziotta M. N. , Mo D. , Niu X. Y. , Pan X. , Parenti A. , Peng W. X. , Peng X. Y. , Perrina C. , Putti-Garcia E. , Qiao R. , Rao J. N. , Ruina A. , Sarkar R. , Savina P. , Serpolla A. , Shangguan Z. , Shen W. H. , Shen Z. Q. , Shen Z. T. , Silveri L. , Song J. X. , Stolpovskiy M. , Su H. , Su M. , Sun H. R. , Sun Z. Y. , Surdo A. , Teng X. J. , Tykhonov A. , Wang J. Z. , Wang L. G. , Wang S. , Wang S. X. , Wang X. L. , Wang Y. , Wang Y. F. , Wang Y. Z. , Wang Z. M. , Wei D. M. , Wei J. J. , Wei Y. F. , Wu D. , Wu J. , Wu S. S. , Wu X. , Xia Z. Q. , Xu H. T. , Xu J. , Xu Z. H. , Xu Z. L. , Xu E. H. , Xu Z. Z. , Xue G. F. , Yang H. B. , Yang P. , Yang Y. Q. , Yao H. J. , Yu Y. H. , Yuan G. W. , Yuan Q. , Yue C. , Zang J. J. , Zhang S. X. , Zhang W. Z. , Zhang Yan , Zhang Yi , Zhang Y. J. , Zhang Y. L. , Zhang Y. P. , Zhang Y. Q. , Zhang Z. , Zhang Z. Y. , Zhao C. , Zhao H. Y. , Zhao X. F. , Zhou C. Y. , Zhu Y. ,   DAMPE Collaboration
Published: January 2025

Precise direct cosmic-ray (CR) measurements provide an important probe to study the energetic particle sources in our Galaxy, and the interstellar environment through which these particles propagate. Uncertainties on hadronic models, ion-nucleon cross sections in particular, are currently the limiting factor toward obtaining more accurate CR ion flux measurements with calorimetric space-based experiments. We present an energy-dependent measurement of the inelastic cross section of protons and helium-4 nuclei (alpha particles) on a Bi4Ge3O12 target, using 88 months of data collected by the DAMPE space mission. The kinetic energy range per nucleon of the measurement points ranges from 18 GeV to 9 TeV for protons, and from 5  GeV/n to 3  TeV/n for helium-4 nuclei. Our results lead to a significant improvement of the CR flux normalization. In the case of helium-4, these results correspond to the first cross section measurements on a heavy target material at energies above 10  GeV/n.

Published by the American Physical Society
2025
A meta-analysis of ESG factors in the real estate investment trusts sector: exploring their impacts on REITs performance
Authors: Zheng Zheng , Lee Chyi Lin 
Published: January 2025

PurposeThis study aims to analyse the inconsistencies found in previous research regarding the impact of environmental, social and governance (ESG) factors on real estate investment trusts’ (REITs) performance. By identifying the individual contributions of each ESG pillar, the research seeks to clarify ESG’s role in determining REIT outcomes.Design/methodology/approachThe study conducts a meta-analysis of 26 selected studies from a pool of over 300 academic papers that investigate the relationship between ESG factors and REIT performance. The meta-analysis aggregates regression findings from these studies, and logistic regression models are used to examine the distinct effects of each ESG factor on REIT performance.FindingsThe results indicate that the environmental and social pillars significantly influence the relationship between ESG and REITs performance. The social factor consistently shows a positive and significant effect, while the environmental factor is significant but with an unclear direction of influence. The governance factor does not show a significant impact, suggesting that under the current REITs regulatory framework, governance is less influential. The results address the distinct contribution of ESG factors in shaping REIT outcomes across different market contexts and time periods. Moreover, the positive impact of the social pillar aligns with Freeman’s (1984) social impact hypothesis, which suggests that business practices associated with stakeholders’ interests positively affect financial performance.Originality/valueThis study enhances the understanding of ESG factors’ impact on REITs by being the first to systematically analyse the underlying reasons for the varied outcomes in previous research. It is also the first attempt to employ meta-analysis in exploring the theoretical foundations of ESG effects within the real estate and construction sectors. The findings assist investors in making more informed decisions based on ESG components and offer guidance for policymakers in crafting regulations that better reflect the influence of ESG factors.