bluuebunny/crossref_metadata_2025_split huggingface dataset:
Soybean response to potassium, magnesium, and sulfur fertilization on Southeastern Coastal Plain soils
Authors: Erhunmwunse Adesuwa S. , Farmaha Bhupinder S. 
Published: January 2023

AbstractPotassium (K), magnesium (Mg), and sulfur (S) are susceptible to leaching in Southeastern Coastal Plain soils and can limit crop production if not properly managed. This study aimed to determine the effect of K, Mg, and S fertilization on soybean [Glycine max (L.) Merr.] yield, tissue nutrient concentrations, and soil K, Mg, and S concentrations. Treatments included three K, two Mg, and two S fertilizer rates arranged in a randomized complete block design with three replications. There was no significant main or interaction effect of K, Mg, and S on soybean yield, even when the initial soil‐test S level was below critical levels. Leaf K concentrations of control plots measured at the R2 growth stage were in the sufficiency range reported for soybean in southeastern states. However, leaf Mg and S concentrations were below the sufficiency ranges. Applying S fertilizer increased leaf Mg and S concentrations, but Mg fertilizer did not affect leaf Mg concentrations. Applying K fertilizer rates increased soil‐test K across three soil depths compared to the control K treatment. The application of Mg fertilizer increased soil‐test Mg more at 0–15 cm than at the other two depths (15–30 or 30–45 cm), whereas S fertilizer application increased soil‐test S more at 15–30 cm. The soil samples taken before experiment initiation showed that the lower two soil depths had greater soil‐test K and S concentrations than at the top layer. These findings indicate that more research is needed to appropriately credit subsoil nutrients while making fertilizer recommendations for soybean grown on Southeastern Coastal Plain soils.
Field evaluation of phosphorus limitation in drinking water biofilters
Authors: Rasmus Madison , Keithley Asher E. , Chambers Bryant A. , Zhou Grace , Pope Greg , Dickenson Eric R. V. , Bzdyra Bradley , Lu Alisa , Kinney Kerry A. , Kirisits Mary Jo 
Published: January 2023

AbstractHydraulic performance issues in drinking‐water biofilters have sometimes been associated with phosphorus limitation and increased production of extracellular polymeric substances in previous bench‐scale studies. However, field studies utilizing phosphorus supplementation to improve biofilter hydraulic performance have produced mixed results. Here, we determined the ratio of activities for phosphatase to glycosidase (PHO:GLY), which are enzymes involved in acquiring orthophosphate and biodegradable organic carbon from complex organic substrates, to assess phosphorus limitation in 21 pilot‐ and full‐scale biofilters. Supplementation of the pilot‐scale biofilter influents with 37 μg/L orthophosphate‐P reduced the PHO:GLY from 1.8–40.3 (mean 14.8) to 0.3–15.9 (mean 5.3), demonstrating that increased orthophosphate availability decreases PHO:GLY. In the absence of phosphorus supplementation, the PHO:GLY of the pilot‐ and full‐scale biofilters ranged from 0.3 to 40.3 (mean 10.1), and no hydraulic performance issues were noted. Thus, severe phosphorus limitation appears uncommon in the field, suggesting that phosphorus supplementation is unlikely to improve hydraulic performance in typical drinking water biofilters.
Improving Electrochemical Activity of P2‐type Na2/3Mn2/3Ni1/3O2 by Controlling its Crystallinity
Authors: Kataoka Riki , Taguchi Noboru , Tada Kohei , Machida Akihiko , Takeichi Nobuhiko 
Published: January 2023

AbstractInvited for this month's cover picture is the work of Dr. Kataoka, Dr. Taguchi, Dr. Tada and Dr. Takeichi at AIST and Dr. Machida at QST. The cover picture shows that the charge‐discharge cycle characteristics have been improved by reducing the particles size of the layered compound Na2/3Mn2/3Ni1/3O2 to the several nm level. Read the full text of the Research Article at 10.1002/batt.202200462.
Teaching “Biochemistry with Elements of Chemistry” in the COVID‐19 pandemic
Authors: Dudzik Paulina , Bentke‐Imiolek Anna , Kocemba‐Pilarczyk Kinga A. , Ostrowska Barbara 
Published: January 2023

AbstractThe purpose of the presented article is to evaluate the students' perception of the online teaching educational model as a part of the “Biochemistry with Elements of Chemistry” course conducted during the COVID‐19 pandemic at the Faculty of Medicine of the Jagiellonian University Medical College. The first part of the article reflects upon the pandemic impact on the transition from the in‐person (standard format) to a complete remote learning format. The next part is based on the responses of the students to a questionnaire and presents an analysis of the students' preferences and perceptions regarding synchronous and asynchronous teaching methods. Students answered questions about the advantages and disadvantages of distance learning programs. They indicated the most suitable learning mode in terms of gaining knowledge and enhancing their motivation to learn. They listed factors that facilitated remote learning as well as those which made it difficult and posed a challenge to adjust to the new system, in all types of classes, that is, lectures, seminars, and laboratories. The last part of this paper presents the results of the students' performance in the pandemic‐enforced system and compares them with the results from the previous class of students from the past year, when teaching was conducted mainly in the standard format. The conclusions from the given analysis may enable beneficial changes for the “Biochemistry with Elements of Chemistry” course for remote teaching in the future. It may also provide valuable insights for such types of courses conducted at other Universities and promote deliberations to continuously improve learning outcomes.
Comparison between a handheld ultrasound device and a traditional ultrasound for performing transcranial sonography in patients with Parkinson's disease
Authors: Paes Maria A. S. , Nicaretta Denise H. , Alvarenga Regina M. P. , Rosso Ana L. Z. , Brisson Rodrigo T. , Fernandes Rita C.L. 
Published: January 2023

AbstractObjectiveThe aim of this study is to compare a portable ultrasound (US) device and a traditional US for performing transcranial ultrasonography (CCT) in patients with Parkinson's disease (PD).MethodsThis is a cross‐sectional, observational, and analytical study. The study recruited a total of 129 individuals from two public hospitals in the city of Rio de Janeiro in a prospective and non‐randomized manner between September 2019 and July 2021 as follows: group A with 31 patients with PD, group B with 65 patients with PD, and group C with 64 healthy individuals. Group A was used to collect data to establish the agreement analysis of the TCS measurements between the two devices. Groups B and C provided data for constructing the receiver operating characteristic curve for the handheld US. The subjects underwent the assessment of the transtemporal bone window (TW) quality, the mesencephalon area, the size of the third ventricle, and the substantia nigra (SN) hyperechogenicity area.ResultsThere was a good agreement between the methods regarding the quality of the TW–Kappa concordance coefficient of 100% for the right TW and 83% for the left, the midbrain area—intraclass correlation coefficient (ICC) of 69%, the SN area ICC = 90% for the right SN and 93% for the left and the size of the third ventricle ICC = 96%. The cutoff point for the SN echogenic area in the handheld US was 0.20 cm2.ConclusionsThe handheld US is a viable imaging method for performing TCS because it shows good agreement with the measurements performed with traditional equipment, and the measurement of SN echogenic area for PD diagnosis presents good sensitivity and specificity.
Late onset of flesh‐colored papules of the neck
Authors: Baklouti Massara , Sellami Khadija , Chaari Chiraz , Tahia Boudaouara , Turki Hamida 
Published: January 2023

AbstractPapular elastorrhexis is a rare, acquired disorder of elastic tissue, occurring in adolescent females, characterized by flesh‐colored monomorphous papules usually located on the trunk and the proximal portion of the extremities. We report a case in an old woman with atypically isolated localization on the neck.
Energy Harvesting: Synthetic Use of Recovered Energy in Electrochemical Late‐Stage Functionalization
Authors: Karl Tobias A. , Seidl Max , König Burkhard 
Published: January 2023

AbstractInvited for this issue's Front Cover is the group of Prof. Dr. Burkhard König of the University of Regensburg (Germany). The cover picture illustrates an induction‐based energy harvesting (EH) device that converts part of the rotational energy of magnetic stirrers back into electrical energy, making it accessible for electrochemical transformations. Just like a satellite hovering in polar orbit, the EH device experiences a constant change in magnetic field orientation when placed on top of a stirring plate. Read the full text of the Research Article at 10.1002/celc.202201097.
Preventable harm because of outpatient medication errors among children with leukemia and lymphoma: A multisite longitudinal assessment
Authors: Wong Chris I. , Vannatta Kathryn , Gilleland Marchak Jordan , Quade Emeric V. , Rodgers Isabelle M. , Reid Christine M. , Dandoy Christopher E. , Billett Amy L. , Miller Tamara P. , Vaughn Shelley , Daraiseh Nancy M. , Liu Shanshan , Carle Adam C. , Walsh Kathleen E. 
Published: January 2023

AbstractBackgroundThere is little longitudinal information about the type and frequency of harm resulting from medication errors among outpatient children with cancer. We aimed to characterize rates and types of medication errors and harm to outpatient children with leukemia and lymphoma over 7 months of treatment.MethodsWe recruited children taking medications at home for leukemia or lymphoma from three pediatric cancer centers. Errors were identified by chart review, in‐home medication review, observation of administration, and interviews. Physician reviewers confirmed error (Fleiss' κ = 0.95), harm (Fleiss' κ = 0.82), and suggested interventions. Generalized linear mixed models with random effects were used to account for clustering by site.ResultsAmong 131 children taking 1669 medications with 367 home visits, 408 errors were identified, including 242 with potential for harm and 39 with harm (1.0 harm per 1000 patient‐days [95% CI, 0.1–9.8]). Ten percent of children were injured by errors and 42% had errors with potential for harm. Twenty‐six percent of caregivers reported that miscommunication led to missed doses or overdoses at home. Children on >13 medications had significantly more serious medication errors than those on fewer medications (77% vs 61%; p = .05). Physician reviewers judged that improved communication among caregivers and between caregivers and clinicians may have prevented the most harm (66%).ConclusionsIn this longitudinal study, 10% children with leukemia or lymphoma experienced adverse drug events because of outpatient medication errors. Improvements addressing communication with and among caregivers should be codeveloped with families and based on human‐factors engineering.Plain Language Summary

In this longitudinal study, medication errors in the clinic, pharmacy, or at home among children with leukemia or lymphoma over a 7‐month period were common, and 10% suffered harm because of errors.

Children on >13 medications had significantly more serious medication errors than those on fewer medications (77% vs 61%; p = .05).

Physician reviewers judged that improved communication among caregivers and between caregivers and clinicians may have prevented the most harm (66%). Improvements addressing communication with and among caregivers should be codeveloped with families and based on human‐factors engineering.
A location‐aware physical unclonable function and Chebyshev map‐based mutual authentication mechanism for internet of surveillance drones
Authors: Nair Aiswarya S. , Thampi Sabu M. 
Published: January 2023

SummaryThe primary concern for securing the Internet of Drones (IoD) is authentication. Drone location is a vital information that must be verified before a secure communication link with the ground station can be established. In this paper, a location aware mutual authentication technique for secure inter‐drone and drone to ground communication using physical unclonable functions and Chebyshev chaotic maps is proposed. This is the first work that addresses the location validation of drones along with server‐less inter‐drone communication with a fail‐safe mechanism designed using a fuzzy inference system to tackle drone failures. The security of the system is analyzed using Burrows–Abadi–Needham logic, real‐or‐random oracle model and ProVerif. The processing, communication, and storage costs of the proposed scheme are determined and compared to other drone mutual authentication protocols. The proposed mechanism outperforms the existing mutual authentication protocols with superior security features and performance attributes and is well suited for surveillance drone networks.
The contribution of the alternative pathway in complement activation on cell surfaces depends on the strength of classical pathway initiation
Authors: de Boer Esther CW , Thielen Astrid JF , Langereis Jeroen D , Kamp Angela , Brouwer Mieke C , Oskam Nienke , Jongsma Marlieke L , Baral April J , Spaapen Robbert M , Zeerleder Sacha , Vidarsson Gestur , Rispens Theo , Wouters Diana , Pouw Richard B , Jongerius Ilse 
Published: January 2023

AbstractObjectivesThe complement system is an important component of innate immunity. The alternative pathway (AP) amplification loop is considered an essential feed forward mechanism for complement activation. However, the role of the AP in classical pathway (CP) activation has only been studied in ELISA settings. Here, we investigated its contribution on physiologically relevant surfaces of human cells and bacterial pathogens and in antibody‐mediated complement activation, including in autoimmune haemolytic anaemia (AIHA) setting with autoantibodies against red blood cells (RBCs).MethodsWe evaluated the contribution of the AP to complement responses initiated through the CP on human RBCs by serum of AIHA patients and recombinant antibodies. Moreover, we studied complement activation on Neisseria meningitidis and Escherichia coli. The effect of the AP was examined using either AP‐depleted sera or antibodies against factor B and factor D.ResultsWe show that the amplification loop is redundant when efficient CP activation takes place. This is independent of the presence of membrane‐bound complement regulators. The role of the AP may become significant when insufficient CP complement activation occurs, but this depends on antibody levels and (sub)class. Our data indicate that therapeutic intervention in the amplification loop will most likely not be effective to treat antibody‐mediated diseases.ConclusionThe AP can be bypassed through efficient CP activation. The AP amplification loop has a role in complement activation during conditions of modest activation via the CP, when it can allow for efficient complement‐mediated killing.
Effect of Storage Time on Wax–Wax–Hydrolyzate Canola Oil Oleogels
Authors: Wettlaufer Till , Flöter Eckhard 
Published: January 2023

AbstractIn this study, two natural waxes, beeswax (BW) and sunflower wax (SFW), are combined with their hydrolyzed variants to deliberately alter the waxes’ composition. The properties of the produced oleogels with different wax inclusion levels (4%, 8%, 12%, and 16% w/w) are investigated after defined intervals (2 days, 7 days, 3 weeks, and 3 months). To do so, the gels are monitored via penetrometry, microscopy, and calorimetry. Although the gels do not show any significant difference during storage in the micrographs, the calorimetric and firmness data reveal meaningful results. The heat of dissolution increases in every system investigated, indicating post‐crystallization processes. Due to different solubilities of wax components, the critical gelling concentration is determined and the solid wax content is retrieved to further address the structure efficiency (S.E.). It is demonstrated that although the quantity of solids over time increases, the scaffolding effectiveness decreases in most cases. Only SFW, most likely due to sintering, shows an increase in S.E. over the storage time. Identified synergistic effects in BW and hydrolyzate mixtures decrease with increasing storage time. This work aims to contribute to a better understanding of the behavior of wax‐based oleogels upon storage.Practical Applications: Although much is known about the gel properties of wax‐based oleogels at short‐term, the behavior over the storage period remains largely unresolved. However, this behavior is immensely important for a real application in fast and slow moving consumer goods. After all, products should always have the same consumer‐relevant properties when stored at variable time frames. This applies to both food and pharmaceutical products. Knowledge of the behavior of wax‐based oleogels in terms of a time‐dependent change can help to choose a targeted product design and ensure product quality and consumer satisfaction.
LC/MS analysis of mushrooms provided new insights into dietary management of diabetes mellitus in rats
Authors: Hussein Abdelaziz , Ghonimy Abdallah , Jiang Hailong , Qin Guixin , El‐Ashram Saeed , Hussein Saddam , Abd El‐Razek Ibrahim , El‐Afifi Tarek , Farouk Mohammed Hamdy 
Published: January 2023

AbstractMushrooms possess antihyperglycemic effect on diabetic individuals due to their nonfibrous and fibrous bioactive compounds. This study aimed to reveal the effect of different types of mushrooms on plasma glucose level and gut microbiota composition in diabetic individuals. The effects of five different mushroom species (Ganoderma lucidum, GLM; Pleurotus ostreatus, POM; Pleurotus citrinopileatus, PCM; Lentinus edodes, LEM; or Hypsizigus marmoreus, HMM) on alloxan‐induced diabetic rats were investigated in this study. The results indicated that LEM and HMM treatments showed lower plasma glucose levels. For the microbiota composition, ACE, Chao1, Shannon, and Simpson were significantly affected by PCM and LEM treatments (p < .05), while ACE, Shannon, and Simpson indexes were affected by HMM treatment (p < .01). Simpson index was affected in positive control (C+) and POM groups. All these four indices were lower in GLM treatment (p < .05). Dietary supplementation of mushrooms reduced plasma glucose level directly through mushrooms' bioactive compounds (agmatine, sphingosine, pyridoxine, linolenic, and alanine) and indirectly through stachyose (oligosaccharide) and gut microbiota modulation. In conclusion, LEM and HMM can be used as food additives to improve plasma glucose level and gut microbiome composition in diabetic individuals.
Extracellular vesicles secreted by triple‐negative breast cancer stem cells trigger premetastatic niche remodeling and metastatic growth in the lungs
Authors: González‐Callejo Patricia , Gener Petra , Díaz‐Riascos Zamira V. , Conti Sefora , Cámara‐Sánchez Patricia , Riera Roger , Mancilla Sandra , García‐Gabilondo Miguel , Peg Vicente , Arango Diego , Rosell Anna , Labernadie Anna , Trepat Xavier , Albertazzi Lorenzo , Schwartz Simó , Seras‐Franzoso Joaquin , Abasolo Ibane 
Published: January 2023

AbstractTumor secreted extracellular vesicles (EVs) are potent intercellular signaling platforms. They are responsible for the accommodation of the premetastatic niche (PMN) to support cancer cell engraftment and metastatic growth. However, complex cancer cell composition within the tumor increases also the heterogeneity among cancer secreted EVs subsets, a functional diversity that has been poorly explored. This phenomenon is particularly relevant in highly plastic and heterogenous triple‐negative breast cancer (TNBC), in which a significant representation of malignant cancer stem cells (CSCs) is displayed. Herein, we selectively isolated and characterized EVs from CSC or differentiated cancer cells (DCC; EVsCSC and EVsDCC, respectively) from the MDA‐MB‐231 TNBC cell line. Our results showed that EVsCSC and EVsDCC contain distinct bioactive cargos and therefore elicit a differential effect on stromal cells in the TME. Specifically, EVsDCC activated secretory cancer associated fibroblasts (CAFs), triggering IL‐6/IL‐8 signaling and sustaining CSC phenotype maintenance. Complementarily, EVsCSC promoted the activation of α‐SMA+ myofibroblastic CAFs subpopulations and increased the endothelial remodeling, enhancing the invasive potential of TNBC cells in vitro and in vivo. In addition, solely the EVsCSC mediated signaling prompted the transformation of healthy lungs into receptive niches able to support metastatic growth of breast cancer cells.
Consumers' valuation for a novel food waste reducing technology: The case of natural coating
Authors: Dsouza Alwin , Fang Di , Yang Wei , Kemper Nathan P. , Nayga Rodolfo M. 
Published: January 2023

AbstractThis study analyzes consumers' valuation for a natural coating that extends the shelf life of produce. Specifically, we examine the effect of providing information about the natural coating's ability to reduce food waste on consumers' willingness to pay (WTP) using bananas and tomatoes as products of interest. We found higher WTP among participants provided with the information. Our study underscores the importance of cognitive and noncognitive factors in understanding the implications of food‐waste related interventions. We also used Query Theory to explore participants' thought processes. The results indicate that those provided with the information generated more value‐increasing thoughts than those not provided with the information.
Potential benefits of intraoperative ultrasound in neurosurgery
Authors: Olah Laszlo , Olah Marton 
Published: January 2023

AbstractComputed tomography and magnetic resonance imaging are the most popular diagnostic tools to visualize intracranial pathology and help surgical planning in the neurosurgical practice. However, these preoperative techniques need to be supplemented with intraoperative methods, if the lesion size may increase or preoperative anatomy may change after the primary imaging due to rapid progression of the underlying intracranial disease. In such situations intraoperative ultrasound could be a valuable technique in real‐time imaging of intracranial pathologic processes, real‐time control of surgical procedure, assistance in drain or catheter placement, and real‐time assessment of residual tumor or hematoma volume during neurosurgical interventions.