bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cost‐utility analysis of a coadjutant telemedicine intervention for fall prevention in Parkinson's disease
Authors: Cubo Esther , Rohani Mohammad , Eissazade Negin , Garcia‐Bustillo Álvaro , Ramírez‐Sanz José Miguel , Garrido‐Labrador José Luis , Olivares‐Gil Alicia , Valiñas‐Sieiro Rn Florita , Allende‐Río Rn Marta , Gonzalez‐Santos Josefa , Gonzalez‐Bernal Jerónimo Javier , Trejo José , Calvo‐Simal Sara , Diez‐Pastor José Francisco , García‐García David , Arnaiz‐González Álvar 
Published: January 2025

AbstractBackground and purposeAdopting telemedicine (TM) enables improved access to specialized care and reduces barriers. The aim was to assess the cost‐utility of a coadjutant multidisciplinary TM programme for fall prevention compared to standard in‐office visits for individuals with Parkinson's disease (PD).MethodsThis was an 8‐month single‐blind randomized controlled trial. TM and control groups received in‐office visits and standard management care at baseline, 4 and 8 months. In addition, the TM group received remote multidisciplinary visits for 4 months. Gait, motor and non‐motor symptoms, daily living activities, balance and frailty were measured using PD‐recommended rating scales and wearable sensors. Clinical characteristics were compared at each visit using baseline scores, gender and age as covariates. The incremental cost‐effectiveness ratio (ICER) and quality‐adjusted life years (QALYs) were calculated at each visit.ResultsFifty patients were included: 25 patients in the TM group (48% males, mean age 71.1 ± 9.0 years) and 25 patients in the control group (52% males, mean age 69.2 ± 9.4 years). Compared to controls, in the TM group similar QALYs were found but, in contrast, significant improvements in daily living activities, depression, apathy, freezing of gait, balance, quality of life and frailty (all p values <0.05). The use of coadjutant TM intervention in addition to in‐office visits was efficient for depression, apathy, freezing of gait, balance and frailty with ICERs, ranging from 91.55 € for non‐motor symptoms to 1677.4 € for frailty.ConclusionsTelemedicine could be considered an efficient coadjutant intervention for PD, especially for non‐motor symptoms, enhancing health outcomes and accessibility.
Investment in By‐Product Benefits (Pseudo‐Reciprocity) Explains the Majority of Help Provided to Non‐Relatives Found in Nature
Authors: Connor Richard 
Published: January 2025

ABSTRACTPseudo‐reciprocity, or investment in byproduct benefits, was introduced originally as an alternative explanation to many claims of reciprocity that followed the classic papers of Trivers and Axelrod and Hamilton. Although widely in use, the term pseudo‐reciprocity has had the unfortunate effect of keeping the concept of Investment in Byproduct Benefits (IBB) in the orbit of reciprocity (reciprocal investments). A recent example is the paper by Carter (2023) linking reciprocity and pseudo‐reciprocity in a continuum of ‘interdependency’ and ‘responsiveness’. As a heuristic exercise, I imagine an alternative history in which the phenomena of byproduct benefits (BB) and IBB were explored fully before the first paper on reciprocity appeared in the literature. This exercise makes clear that the simple concepts of BB and IBB, when joined with kin selection, would lead to a very reasonable description of most cases of cooperation in nature, including market effects, such as partner choice and control. Reciprocity would have claimed its rightful place as a fascinating concept, clearly important in humans and perhaps requiring specific cognitive abilities, that might emerge from the complex web of cooperation in social animals that included kin selection, BB, and IBB. In this context, continua between reciprocity and investment in byproduct benefits are useful. However, the scope for IBB is much broader than reciprocity. IBB, along with reciprocity and kin selection, is one of the key evolutionary mechanisms explaining the origin of helping behavior or ‘investment’ in others of the same and different species, occurring in many contexts where it is not usefully linked to reciprocity. Going forward, it will be helpful to remove IBB from the orbit of reciprocity by using of the term Investment in Byproduct Benefits (IBB) rather than pseudo‐reciprocity.
Return of a racehorse to racing after iatrogenic lipoid pneumonia
Authors: McCullagh S. , Dosi M. C. M. , Keen J. A. , Parkinson N. , Tay A. , McGorum B. C. 
Published: January 2025

SummaryThere is a paucity of literature describing equine lipoid pneumonia (LP) caused by inadvertent intrapulmonary administration of liquid paraffin (mineral oil). This case report improves our understanding of LP by describing; (1) the first reported return of a horse to racing after LP, (2) the likely benefits of prolonged dexamethasone administration, (3) the detailed short‐ and long‐term pulmonary and systemic responses to intrapulmonary liquid paraffin and (4) the prolonged pulmonary retention of liquid paraffin.
Clinical findings of candidate stallions presented for licensing at all German Warmblood horse‐breeding associations in 2018–2020
Authors: Folgmann Muriel Sarah , Stock Kathrin Friederike , Feige Karsten , Delling Uta 
Published: January 2025

AbstractBackgroundThere is very little information available about the health status of young stallions from the German Warmblood population that will, once licensed, shape the future of equestrian sport and horse breeding.ObjectivesTo evaluate the prevalence of clinical findings at licensing examinations of candidate stallions and the influences of season of birth, age at licensing, year of licensing, and the evaluator on the distribution of recorded findings.Study designRetrospective observational study.MethodsClinical records of 1655 candidate stallions presented for licensing in 2018–2020 were reviewed. Data were provided by all German Warmblood horse‐breeding associations and their official veterinarians. Storage and processing of the records was performed using the German equine health database. Generalised linear models were used to determine the influences of fixed effects (season of birth, age at licensing, year of licensing, evaluator) on main clinical findings. The significance level was set at p < 0.05.ResultsNo remarks were documented on the clinical examination protocol in 777 of the 1655 horses (47.0%). Furthermore, 51.9% of those stallions with remarks had only one finding documented. The main abnormalities recorded were skin lesions, enlargements on the limbs, and testicular findings. The distributions of several clinical findings differed significantly between the evaluators.Main limitationsHomogenous study population and retrospective data.ConclusionsThe clinical part of the licensing examination of German Warmblood candidate stallions presented in 2018–2020 rarely revealed abnormalities. The majority of the clinical findings which were recorded are considered to be of minor clinical relevance, implying an overall favourable clinical health status of the presented stallions.
Rethinking Museum Geographies: Towards Restitution and a Relational Ethics of Care in Legacies of Colonialism
Authors: Warren Saskia 
Published: January 2025

ABSTRACTThis article identifies how a critical exploration of museums and restitution processes illuminates geographical thinking on relational ethics and care. In legacies of colonialism, critical approaches to museums and restorative action show a need to address colonial violence and dispossession from stolen cultural heritage. Restorative action reveals emergent, and more hopeful, practices of care across relational geographies. Research on relational ethics, Indigenous and postcolonial spatial approaches, and geographies of care expands frameworks of understanding in critical museum geographies. It advances that a relational ethics through restitution processes can foster translocal and transnational circuits of learning and exchange, in more care‐full museum geographies.
Planetary Futures: On Life in Critical Times
Authors: Verne Julia , Marquardt Nadine , Ouma Stefan 
Published: January 2025

ABSTRACTBased upon the opening keynote address at the German Congress of Geography held in Frankfurt am Main in 2023, this article traces the current debate on the planetary in the humanities, social sciences and Earth System Science in three parts. Instead of taking the concept of the planetary for granted, we explore the question of how it is reflected in our respective fields of research (cultural geography, social geography, and economic geography) and what potential it harbors for unearthing new insights. In particular, we consider the possibilities for a planetarily‐oriented cultural geography beyond anthropocentrism, a social geography of housing that focuses on the concept of planetary habitability, and an economic geography that centers the trans‐historical and trans‐geographical impact of plantation logics. From our point of view, the planetary is not simply an additional scale but rather a style of thought that increasingly characterizes our present. Since natural and social science approaches meet here in a new way, it seems particularly relevant to ask how we as geographers might allow ourselves to be intrigued and unsettled by the planetary.
Evaluation and Comparison of the Efficacy and Safety of Erbium YAG Laser Along With Normal Saline vs. Its Combination With Stromal Vascular Fraction (SVF) and Platelet‐Rich Plasma (PRP) in the Treatment of Striae Distensae: A Double‐Blind Randomized Clinical Trial
Authors: Roohaninasab Masoumeh , Mahdi Zeinab , Zare Sona , Dehghani Abbas , Goodarzi Azadeh , Najar Nobari Niloufar , Zeinali Roya , Nouri Maryam , Ebrahimi Zahra , Nilforoushzadeh Mohammad Ali , Behrangi Elham 
Published: January 2025

ABSTRACTBackgroundThere is no definitive solution for the treatment of striae distensae (SD), and effectiveness of each treatment method remains controversial. We aimed to investigate and compare the efficacy of the combination of Erbium YAG (Er:YAG) laser and stromal vascular fraction (SVF), the combination of Er:YAG laser and platelet‐rich plasma (PRP) and Er:YAG laser plus saline in the treatment of SD.Materials and MethodsIn 12 participating patients with at least three lesions (36 lesions in total), each lesion was treated with an Er:YAG laser. SVF was randomly injected intradermally for the first lesion, PRP for the second lesion, and normal saline as placebo for the third lesion. Treatment duration was one session, and the safety and efficacy of the treatment was assessed 3 months later using the following items: evaluation of biometric parameters including corneometery, erythema, melanin, tewametery, color, cutometery, complete thickness, epidermal thickness, dermal thickness, complete density, epidermal density, and dermal density; assessment of patient and physician satisfaction using Likert score; and recording of adverse effects of treatment.ResultsThe study involved 12 patients (evaluating 36 lesions in total), predominantly women (83%), with an average age of 39.16 years. The analysis revealed significant improvements in biometric indices, including complete thickness, epidermal thickness, dermal thickness, and R5 cutometer readings across all groups after the intervention. Notably, the SVF and PRP groups showed statistically significant enhancements in dermal and complete density compared to the placebo group. The SVF group demonstrated a significant increase in epidermal density (from 45.95 to 51.19, p = 0.001), unlike the PRP and placebo groups which showed nonsignificant changes. Comparing the average changes in biometric factors, the SVF group exhibited significantly greater increases in complete thickness, dermal thickness, complete density, epidermal density, and dermal density than the other groups. Both patient and physician satisfaction scores were highest in the SVF group (p = 0.001), with no significant posttreatment complications reported.ConclusionOur results showed that the combination of Er:YAG laser and SVF injection could be considered an effective and safe treatment method in the treatment of SD.Trial RegistrationIRCT20200127046282N14
Population Diversity and Economic Growth: A Meta‐Regression Analysis
Authors: Sintos Andreas 
Published: January 2025

ABSTRACTIn this study, we apply meta‐regression techniques to 1537 estimates derived from 83 studies that investigate the effect of population diversity on economic growth. We find a subtle inclination toward publishing results that assert a negative correlation between diversity and economic growth, indicating a mild publication bias. However, the extent and direction of this bias vary according to the specific diversity dimension considered. After adjusting for both publication bias and the methodological quality of the underlying studies, our results indicate that while ethnic and linguistic diversity exhibit a small and statistically insignificant positive effect on economic growth, the remaining diversity dimensions—namely religious, genetic, birthplace, and other forms of diversity—exert a significant positive impact on growth, with effect sizes ranging from moderate to large. Additionally, our findings reveal that the reported estimates are influenced by several factors, including the methodologies employed by researchers in measuring economic growth and diversity, the characteristics of the data and estimation techniques utilized, and the consideration of other growth‐related factors.
The Burden of Hepatitis B and C in Asia, 1990–2019: An Update Analysis From the Global Burden of Disease Study 2019
Authors: Chen Qi , Huang Shu , Peng Jieyu , Wang Ping , Shi Xiaomin , Luo Rui , Xu Huan , Zhang Wei , Shi Lei , Peng Yan , Yuan Fangfang , Tang Xiaowei 
Published: January 2025

ABSTRACTAimThis research was aimed to uncover the hepatitis B virus (HBV) and hepatitis C virus (HCV) related diseases burden in Asia over the past 3 decades, estimating from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019.MethodsAge‐standardised rates, case numbers of prevalence, disability‐adjusted life‐years (DALYs), incidence and deaths with 95% uncertainty intervals (UI) for HBV/HCV‐related diseases from 1990 to 2019 were derived from GBD 2019 database, with the estimated annual percentage changes (EAPCs) calculated. Our analysis also encompassed the association between the Sociodemographic Index (SDI) and the burden of HBV/HCV‐related diseases, future disease burden predictions in six selected countries and various risk factors.ResultA general downward trend in the age‐standardised rates of death, disability‐adjusted life years (DALYs), prevalence and incidence for both HBV and HCV‐related diseases was observed in Asia during the past 30 years. Despite overall declining trends, some analysed diseases experienced an increase. Compared with females, the disease burden was greater in the male population and peaked in the age of 50–54 for both sexes. It is significant for the HBV‐related and HCV‐related diseases burden in Afghanistan, Cambodia, Mongolia and Pakistan. Drug use and smoking were prominent contributors to HCV and HBV‐related diseases. There was a negative relationship between the burden of HCV and HBV‐related diseases and SDI.ConclusionAlthough decreases were observed in Asia, the HBV‐ and HCV‐associated diseases burden remained high, highlighting that imperative measures for prevention and treatment should be taken by governments in Asia.
Imperial uses of non‐territorial autonomy: The projects of André Mandelstam and Boris Nolde
Authors: Khripachenko Tatiana 
Published: January 2025

AbstractThe article explores imperial uses of non‐territorial autonomy in the works of international lawyers André Mandelstam and Boris Nolde, which they wrote before the collapse of the Russian Empire. Although written in different contexts, their projects for non‐territorial autonomy departed from other similar plans proposed in the Russian Empire. Rather than an attempt to secure the status and the interests of ethno‐national groups within the framework of a multinational state, they pursued the goal of imperial domination and regarded the rights of minorities as a pretext for imposing limitations on other states (or states in the making). The project of André Mandelstam was a part of Russia's Plan of Reforms for the Ottoman Empire produced in 1913/1914, which aimed to protect its Armenian population, yet severely restricted the sovereignty of the Sultan. Written in July 1917, Boris Nolde's project developed the programme of the Constitutional Democratic Party on the national question. He was particularly concerned with the recognition of Ukrainian national‐territorial autonomy by the Provisional Government. For him, non‐territorial autonomy was an instrument of undermining the claims of the Ukrainian national movement and retaining control over Ukraine.
A Rapid and Reversible Molecular “Switch” Regulating Protein Expression in Chlamydomonas reinhardtii
Authors: Li Xinyi , Wang Song , Li Qianyi , Li Xiangyu , Lin Sirao , Zhao Wenyu , Liu Yingqi , Wu Bowen , Huang Ying , Jia Bin , Hu Zhangli 
Published: January 2025

ABSTRACTChlamydomonas reinhardtii, a prominent chassis in synthetic biology, faces limitations in regulating the expression of exogenous genes. A destabilization domain (DD)/Shield‐1 system, originally derived from mammals, offers a ligand‐dependent control of stability, making it a valuable tool. This system utilises the destabilization domain to induce rapid degradation of target protein unless stabilised by Shield‐1, a synthetic ligand. Upon the addition of Shield‐1,the degradation is halted, leading to the accumulation and stabilisation of the target protein. This system has demonstrated successful regulation of foreign protein expression in mammals, parasites, and plants. In this study, the DD/Shield‐1 system was harnessed to regulate the expression of the paromomycin resistance gene and luciferase encoding gene in Chlamydomonas, revealing its capability for rapid, stable, and reversible protein expression regulation in microalgae, serving as a molecular switch. Furthermore, this regulation exhibits reagent dependency, enhancing its applicability in practical production. A strain with induced expression of the gene‐editing protein, LbCas12a, was successfully constructed and then tested for gene editing. The findings not only enrich the toolkit for Chlamydomonas molecular studies but offer a promising technique for regulating the expression and validating the functionality of exogenous proteins in microalgae.
Effects of transcranial photobiomodulation on fine motor skills in boccia para‐athletes
Authors: de Morais Garcez Edna , Baptista Alessandra , Hamblin Michael R. , Suzuki Selly S. , Garcez Aguinaldo , Nunez Silvia Cristina , Navarro Ricardo S. , Bassoto Thamiris , Garcez Aguinaldo Silva 
Published: January 2025

AbstractThis study investigated the effects of transcranial photobiomodulation (t‐PBM) on para‐athletes' manual dexterity and intralimbal coordination. Six para‐athletes from a Boccia Team participated. t‐PBM was administered using a LED helmet with 204 LEDs (660 and 850 nm) emitting 10 mW each, delivering 9 J/cm2 per LED during 15‐min sessions three times a week. The trial lasted 2 weeks, with baseline, placebo treatment, and post‐treatment assessments. Manual dexterity was measured by Box and Ball Test (BBLT), and intralimbal coordination by discrete and continuous horizontal and vertical touch tests. Results showed significant improvements in manual dexterity for the t‐PBM group compared to the placebo. Discrete vertical touch tests showed reduced time to perform movements, and continuous vertical touch tests showed increased movement frequency in the t‐PBM group. No significant improvements were observed in the placebo group. t‐PBM was shown to be a potentially effective treatment, with significant benefits in fine motor skills.
Cartesian know‐how
Authors: Morales Carbonell Felipe , González Rodrigo 
Published: January 2025

AbstractIn this article, we examine the prospect of extracting an account of know‐how from Descartes's philosophy. Against the traditional take, we argue that Descartes's views on know‐how cannot be simply reduced to his account of theoretical knowledge. The key to understanding Descartes on know‐how is to examine his accounts of moral certainty and the relation between the mind and the body in action.
From human to superhuman: the impact of the microbiome on physiology
Authors: Keely Stephen J. , Cotter Paul D. , Wahlstrom Annika , Schellekens Harriët , Weinkove David , Barrett Kim E. 
Published: January 2025

AbstractThe complex microbial community residing in the human gut has long been understood to regulate gastrointestinal physiology and to participate in digestive diseases, but its extraintestinal actions and influences are increasingly recognized. This article discusses bidirectional interactions between the gut microbiome and athletic performance, metabolism, longevity and the ability of the gut–brain axis to influence cognitive function and mental health.
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Enhancement of Synchronization in Nonlinear MEMS Oscillator Based on Electrothermal Adjustment
Authors: Xiao Zunhao , Shi Zhan , Wang Xuefeng , Chuang Kuo-Chih , Lv Qiangfeng , Wei Xueyong , Huan Ronghua 
Published: January 2025

Abstract
Synchronization in microelectromechanical systems (MEMS) typically encounters the impact of electrothermal phenomena, often in conjunction with piezoresistive detection or frequency tuning. However, the electrothermal effects on synchronization have not been previously explored. This paper investigates the electrothermal effects on synchronization bandwidth and frequency stability in a nonlinear MEMS arch oscillator. Experimental results demonstrate a non-monotonic pattern in synchronization bandwidth as electrothermal current increases, corroborated by theoretical models based on quality factors and equivalent nonlinearity. Drawing from theoretical analysis, which suggests that synchronization can be enhanced by adjusting feedback and perturbation strength, we achieved a 5.72-fold enhancement in synchronization bandwidth in our experiments. Furthermore, we observed that increased electrothermal significantly improves frequency stability. We developed a model based on the Allan deviation that incorporates electrothermal temperature to evaluate frequency stability, and this model successfully verified our experimental results. These experimental and theoretical findings highlight the potential of electrothermal effects to enhance synchronization and frequency stability in MEMS devices, paving the way for more robust sensor technology applications.
Congenital cytomegalovirus pneumonia presents as pleural effusion in infancy
Authors: Rajvanshi Nikhil , Yadav Taruna , Kumar Prawin , Goyal Jagdish Prasad 
Published: January 2025

Cytomegalovirus (CMV) infection is one of the most common congenital infections. We present a case of an infant who presented with respiratory distress since birth with a normal antenatal history. The infant had bilateral pleural effusion. He was malnourished with a small head. Chest auscultation revealed bilateral diffuse crepitation. The chest radiograph showed diffuse haziness with the interstitial pattern. Contrast-enhanced CT of the thorax showed diffuse areas of ground glass opacities with peribronchial thickening and patchy atelectasis in bilateral lower lobes. Detailed evaluation showed positive IgM CMV antibodies with >1000 copies/mL of CMV on urinary PCR. Hearing evaluation revealed bilateral moderate hearing loss.This case emphasises that CMV may present as pneumonitis at birth. Early diagnosis and treatment are of paramount importance in such cases, as it can prevent permanent end-organ damage.