bluuebunny/crossref_metadata_2025_split huggingface dataset:
Usefulness of the Endoscopic Surgical Skill Qualification System for laparoscopic colectomy for transverse colon cancer: a Japanese multicenter analysis
Authors: Ishimaru Kazuhide , Tominaga Tetsuro , Nonaka Takashi , Hisanaga Makoto , Takeshita Hiroaki , Fukuoka Hidetoshi , To Kazuo , Tanaka Kenji , Sawai Terumitsu , Nagayasu Takeshi 
Published: February 2023

Abstract
Purpose
Laparoscopic colectomy for transverse colon cancer (TCC) can be technically demanding due to the anatomical complexity of the region. In Japan, the Endoscopic Surgical Skill Qualification System (ESSQS) was established to improve the skill of laparoscopic surgeons and further develop surgical teams. We examined the safety and feasibility of laparoscopic colectomy for TCC, and evaluated the effects of the Japanese ESSQS in facilitating this approach.
Methods
We retrospectively reviewed 136 patients who underwent laparoscopic colectomy for TCC between April 2016 and December 2021. Patients were divided into an expert group (surgery performed by an ESSQS-qualified surgeon, n = 52) and a non-expert group (surgery performed by an ESSQS-unqualified surgeon, n = 84). Clinicopathological and surgical features were compared between groups.
Results
Postoperative complications occurred in 37 patients (27.2%). The proportion of patients who developed postoperative complications was lower in the expert group (8.0%) than in the non-expert group (34.5%; p < 0.017). Multivariate analysis revealed “Operation by ESSQS-qualified surgeon” (Odds ratio [OR] 0.360, 95% confidence interval [CI] 0.140–0.924; p = 0.033), blood loss (OR 4.146, 95%CI 1.688–10.184; p = 0.002) and clinical N status (OR 4.563, 95%CI 1.814–11.474; p = 0.001) as factors independently associated with postoperative complications.
Conclusion
The present multicenter study confirmed the feasibility and safety of laparoscopic colectomy for TCC and revealed that ESSQS-qualified surgeons achieved better surgical outcomes.
Innovative low-cost engineered adsorbents based on waste eggshell for nickel removal from aqueous solutions
Authors: SEGNEANU Adina-Elena , TRUSCA Roxana , CEPAN Claudiu , MIHAILESCU Maria , MUNTEAN Cornelia , Grozescu Ioan 
Published: February 2023

Abstract

In the current circular economy, innovation is requisite for waste reuse into new efficient materials designed to minimize pollution and conserve non-renewable natural reserves. Water pollution is a global problem with health, quality of life and food security reverberations.In this study were prepared two newly low-cost engineered adsorbents from eggshells for nickel retention from aqueous solutions. SEM results showed that, in the first adsorbent (EZ), the zeolite nanoparticles were loaded in the eggshell pores. The preparation route for the second adsorbent led to the double functionalization of the eggshell with the nano-sized particles of zeolite and simultaneously eggshell pores and zeolite surface loading with FeOOH particles. The eggshell structural modification was confirmed by the BET analysis. These features enabled the proposed adsorbents to remove nickel with high performance and adsorption capacities of 321.11 mg/g and 287.9 mg/g. The adsorption kinetics and isotherm data follow the Freundlich model (ΔG<0, ΔH<0; ΔS>0) and pseudo-second-order kinetics model. These results indicate that nickel adsorption on adsorbents is a multi-molecular layer, spontaneous and endothermic process. Subsequently, the desorption results exhibit the higher reusability of both adsorbents. This study's outcomes conclude the use of waste to design new, low-cost, and highly efficient engineered adsorbents.
DLGNet: Adversarial Reinforcement Learning for Disease Label Generation
Authors: Yang Ce , Chen Zhenghan , Wang Ye , Tang Xunzhu 
Published: February 2023

Abstract
International Classification of Diseases (ICD) coding has been considered as a multi-label prediction problem, requiring the assignment of one or more codes to a detailed discharge summary. Existing automatic ICD coding algorithms struggle to effectively classify medical diagnosis texts representing deep sparse categories. We propose Disease Label Generation Network (DLGNet), a novel adversarial network that transforms ICD codes into a label generation challenge. This strategy faces three major challenges: (1) How to extract the relationship between clinical text and ICD codes? (2) What training methods should be used to improve the generalization and effectiveness of network? (3) How to evaluate the quality of disease labels generated by the DLGNet? For (1), we develop an information integration module (MIM) to encode the relationship between clinical text and ICD codes. For (2), we present adversarial training algorithms, such as reinforcement causal learning and adversarial perturbation regularization. For (3), we present a Label Discriminator (LD) that calculates the reward for each ICD code in the Label Generator (LG). In conclusion, DLGNet outperforms existing state-of-the-art approaches on evaluation measures such as micro-F1, leading to the formation of a new SOTA. The code is available at anonymous github link: https://anonymous.4open.science/r/DLGNet-787D.
The influence of sociodemographic factors on COVID-19 vaccine mandate acceptance: a cross-sectional study
Authors: Smith David , Zhu David T. , Hawken Steven , Bota A. Brianne , Mithani Salima S. , Marcon Alessandro , Pennycook Gordon , Greyson Devon , Caulfield Timothy , Graves Frank , Smith Jeff , Wilson Kumanan 
Published: February 2023

Abstract
Introduction
Vaccine certificates have been implemented worldwide, aiming to promote vaccination rates and to reduce the spread of COVID-19. However, they are not without controversy and have been criticized for infringing upon medical autonomy and individual rights.
Methods
We administered a national web-based survey exploring public attitudes towards vaccine mandates, vaccine acceptance, and demographic variables. We conducted a multivariate linear regression which revealed key social and demographic factors that were predictive of vaccine certificate acceptance in Canada.
Results
Self-reported minority status (p<0.001), rurality (p<0.001), political ideology (p<0.001), age (p<0.001), having children under 18 in the household (p<0.001), education (p=0.014), and income status (p=0.034) were significant predictors of attitudes towards COVID-19 vaccines and mandates. We found that the most common reasons for COVID-19 vaccination included personal health and safety, protecting others, and travel/work requirements. In contrast, the most common reasons for refusing COVID19 vaccination include perceived violations of personal freedoms, health and safety concerns, and a lack of perceived threat of COVID-19.
Conclusion
The present findings are valuable for their ability to inform the implementation of vaccine certificate which may require targeted communication between public health agencies and under-vaccinated populations.
Origin of gem-quality turquoise associated with quartz-barite veins in western Hubei Province, China: Constraints from mineralogical, fluid inclusion, and C-O-H isotopic data
Authors: Li Wen-Tian , Jiang Shao-Yong , Zhang Hao , Cui Pei-Long 
Published: February 2023

Abstract
Two types of turquoise, including homogeneous Cu-rich turquoise and oscillatory zoned turquoise-planerite series, are recognized in association with quartz-barite veins hosted by Cambrian carbonaceous slates from western Hubei Province of China. Combined fluid inclusion and Raman micro-spectroscopic data reveal that turquoise-bearing barite-quartz veins contain three types of fluid inclusions (pure CH4-N2, carbonic-aqueous, and aqueous), suggesting the responsible fluid is of carbonic-aqueous composition with low oxygen fugacity. Pressure-corrected homogenization temperatures in quartz and barite show a range from 325 to 485 °C and 186 to 391 °C, respectively. Carbon, oxygen, and hydrogen isotopic data suggest that the mineral-forming fluids have a mixed metamorphic-organic affinity, in which the fluids have δ18O and δD values of 15.0 to 18.8‰ and –111 to –93‰, respectively. Generally, the formation of quartz-barite-turquoise veins could be triggered by prior metamorphic devolatilization, followed by the interaction of fluids with country rocks enriched in carbonaceous material, which resulted in the leaching of Cu, Fe, P, and Al from chalcopyrite, pyrite, magnetite, monazite, xenotime, apatite, feldspar, and muscovite in the wall rocks. Decomposition of the organic matter in the carbonaceous slates, caused by regional metamorphism and deformation, could also promote the concentration and transportation of necessary metals for the turquoise. Thus, we propose a new model and suggest that the turquoise gem deposits in western Hubei Province of China belong to the non-magmatic hydrothermal vein type deposit, not the previously proposed supergene origin. The turquoise-forming fluids were characterized by the coexistence of two immiscible fluids of nonmagmatic affinity (i.e., moderate to high-temperature and low-salinity aqueous fluid and pure CH4-N2 fluid formed by interaction with carbonaceous slates). The bluish green homogeneous turquoise in the metamorphic quartz-barite-turquoise veins evolved toward the turquoise-planerite solid solution series as the metal-leaching capability of the aqueous fluids decreased.
Correlation between Hinckley index and stacking order-disorder in kaolinite
Authors: Rao Wenxiu , Liu Xin , Lv Guocheng , Liu Meng , Wang Lijuan , Niu Jinan , Li Zhaohui , Liao Libing 
Published: February 2023

Abstract
Hinckley index (Hi) can be used to characterize the crystallinity of kaolinite. Stacking order-disorder in kaolinite can considerably affect its crystallinity. However, the correlation between Hi and stacking order-disorder in kaolinite has not been reported thus far. Herein, the correlation between stacking order-disorder in kaolinite and Hi was investigated via experiments (XRD, IR spectroscopy, TG-DSC), molecular simulation, and structure refinement. First, we experimentally discovered that the stacking order-disorder in kaolinite changed the relative position between two adjacent structural layers, mainly affecting the interlayer forces. When the kaolinite layers are orderly stacked, the inter-layer force is higher and the stacking lattice energy is lower. The lattice energy of kaolinite in different stacking states was simulated and analyzed using first-principles calculation. It was determined that the kaolinite layers are orderly stacked when two kaolinite layers have zero shift and disorderly stacked otherwise. Finally, through structural refinements, we proposed a new crystallinity index based on stacking order-disorder in kaolinite (crystallinity index based on stacking, CIS). CIS was well fitted to Hi (R2 = 0.986), indicating that kaolinite crystallinity, characterized by Hi, is essentially the ratio of orderly stacking to total stacking (the sum of ordered and disordered stacks). Furthermore, measuring Hi is difficult when kaolinite crystallinity is poor; however, CIS can be used alternatively. This study of the crystallinity of kaolinite will have important significance for its industrial application.
Swarm intelligence machine-learning-assisted progressive global optimization of DNAPL-contaminated aquifer remediation strategy
Authors: Zhang Yunfeng , Chen Huanliang , Lv Minghui , Hou Zeyu , Wang Yu 
Published: February 2023

Abstract
Remediation projects of DNAPL-contaminated groundwater generally face difficulties of low contaminant removal rate and high remediation cost. Hence, a machine-learning-assisted mixed-integer multi-objective optimization technique was presented for efficiently programming remediation strategies. A swarm intelligence multi-kernel extreme learning machine (SI-MKELM) was proposed to build a reliable intelligent surrogate model of the multiphase flow numerical simulation model for reducing the computational cost of repetitive CPU-demanding remediation efficiency evaluations, and a hyper-heuristic homotopy algorithm was developed for progressively searching the global optimum of the remediation strategy. The results showed that: (1) The multi-kernel extreme learning machine improved by swarm intelligence algorithm significantly improved the approximation accuracy to the numerical model, and the mean residual and mean relative error were only 0.7596% and 1.0185%, respectively. (2) It only took 0.1 s to run the SI-MKELM. Replacing the numerical model with SI-MKELM considerably reduced the computational burden of the simulation–optimization process and maintained high computational accuracy for optimizing the DNAPL-contaminated aquifer remediation strategy. (3) The hyper-heuristic homotopy algorithm was capable of progressively searching the global optimum, and avoiding premature convergence in the optimization process. It effectively improved the searching ability of the traditional heuristic algorithms.
Hydrological performance of rain gardens having Calendula officinalis plant with varied planting mixtures
Authors: Kumar Sandeep , Singh Krishna Kumar 
Published: February 2023

ABSTRACT

The rain gardens (RGs) have been one of the best management practices in cities to reduce the impact of urban flooding. However, very little is known about various design parameters of RGs, viz., the type of plantation, planting mixtures, and RG dimensions. This study pertains to examining the influence of planting mixtures on the variations of percolation rates of the RG with Calendula officinalis plant and without plants. Six types of planting mixtures in different experimental RGs have been tried. It has been observed that the percolation rate increases with a higher percentage of compost in the planting mixture for RGs with and without plants. The percolation rate is highest for the planting mixture having 25% compost. The runoff rate reduces with a higher percentage of compost in the planting mixture for RGs with C. officinalis and bare surfaces. No runoff is produced in RGs with plant having a compost of more than 20% in the planting mixture. The outcome of the study will be useful in deciding the composition of the planting mixture which will keep the RG plant healthy and at the same time improve the hydrological performance leading to lowering urban flooding magnitude.
Tight Junctions in the Auditory System: Structure, Distribution and
Function
Authors: Gao Xiang , Chen Changsheng , Shi Shuai , Qian Fuping , Liu Dong , Gong Jie 
Published: February 2023

Abstract:
Tight junctions act as a barrier between epithelial cells to limit the transport of the paracellular substance, which is a required function in various tissues to sequestrate diverse microenvironments and maintain a normal physiological state. Tight junctions are complexes that contain various proteins, like transmembrane proteins, scaffolding proteins, signaling proteins, etc. Defects in those tight junction-related proteins can lead to hearing loss in humans which is also recapitulated in many model organisms. The disruption of the barrier between the endolymph and perilymph caused by tight junction abnormalities will affect the microenvironment of hair cells; and this could be the reason for this type of hearing loss. Besides their functions as a typical barrier and channel, tight junctions are also involved in many signaling networks to regulate gene expression, cell proliferation, and differentiation. This review will summarize the structures, localization, and related signaling pathways of hearing-related tight junction proteins and their potential contributions to the hearing disorder.
Aloe-emodin Quantification using HPTLC and RP-UHPLC in
Extracts and Commercial Herbal Formulations: Evaluation of
Antimicrobial and Antioxidant Effects
Authors: Ahmad Sufiyan , Dakne Ganesh , Taleuzzaman Mohamad , Sarafroz Mohammad , Yadav Pankaj , Khatoon Yasmin , Haque Ziyaul 
Published: February 2023

Background:
High-performance thin-layer chromatography (HPTLC) was
developed and validated for the determination of aloe-emodin in accordance with ICH
guidelines. In addition, a novel RP-UHPLC method was developed, and both methods
were used to analyse the herbal extract and herbal formulation.

Methods:
Separation was carried out on a silica gel 60 F254 HPTLC plate using the mobile
phase Toluene: Methanol (9:1). The linearity was good across the 800-4000 ng/spot
range. Validation results are within acceptable limits. The percent RSD for accuracy was
0.58-1.77, and precision was 1.10-1.97 and 1.45-1.94 for intraday and interday, respectively.
The percentage of aloe-emodin found in the herbal extract and aloe vera capsule
was 99.83 ± 1.19 and 99.53 ± 1.29, respectively, using this method.

Results:
Quantification of aloe-emodin in herbal extract and herbal formulation were
done using a novel UHPLC method with chromatographic conditions of orthophosphoric
acid Methanol (0.1 percent OPA): Water (65:35, v/v) and pH 3, a flow rate of 1.2
ml/min, and elute detection at 254 nm. At 6.32 minutes, a sharp and symmetric peak was
observed. The method developed was validated in accordance with ICH guidelines. The
percent RSD numerical value of accuracy was 0.304-0.576, and the inter-day and intraday
precision were 0.32-3.08 and 0.51-2.78, respectively. Herbal extract and aloe vera
capsule were analysed using the new UHPLC method. Aloe-emodin percentages were
reported as 100.3 ± 0.89 and 99.53 ± 1.29, respectively.

Conclusion:
The antimicrobial and anti-oxidant activities of an aloe-vera herbal formulation
were studied, and the results were positive.
Vilkaču mantinieki. Vēsturiskais un laikmetīgais Jāņa Mauliņa romānā “Pēdas” (1980)
Authors: Mintaurs Mārtiņš 
Published: February 2023

Rakstā aplūkots Jāņa Mauliņa vēsturiskais romāns “Pēdas”, pievēršot uzmanību tā tapšanas apstākļu kontekstam. Romāns publicēts 1980. gadā, tajā atspoguļota situācija 17. gadsimta pirmajā pusē Vid­zemes austrumu daļā. Sižeta pamatā ir stāsts par zemnieku pretestību kungiem, tā alegoriski saistīta ar latviešu situāciju padomju okupācijas laikā. Tādējādi romānu iespējams interpretēt postkoloniālā diskursa ietvaros kā rakstnieka konstruētu ideālā Latvijas modeļa paraugu. Romāns turpina nacionālā romantisma tradīciju vēsturiskajā prozā, pielāgojot to 20. gadsimta otrās puses situācijai. Pēc romāna motīviem 1983. gadā Rīgas kinostudijā uzņemta filma “Vilkatis Toms”, rakstā salīdzinātas romāna un filmas vēstījuma īpatnības.
Hunter-Gatherer Bone and Antler Implements in Lithuanian Coastal Area: Recent Studies in Chronology, Technology and Decoration Patterns
Authors: Rimkus Tomas 
Published: February 2023

Stone Age bone and antler implements are an essential study material, as they contain important information on hunter-gatherer tool making technology, dynamics in hunted animal species, choices of raw materials and much more. Some specimens have unique engravings and incisions on their surface, enabling the studies of the decoration patterns. Moreover, organic finds can be dated by radiocarbon, allowing to approach osseous technologies from a chronological aspect. The Early and Middle Holocene sites containing hunter-gatherer bone and antler implements in Lithuanian coastal area have been discovered and investigated in the last century. The Middle Holocene osseous collection, however, has been studied only recently, shedding light on the manufacturing techniques and chronology of the tools. This paper summarizes the combination of technological, radiocarbon and decoration data of osseous implements found in Palanga and Smeltė sites, as well as the single finds (ca. 6000–3800 cal BC) discovered along the coast of Lithuania.
U.S. Legation in Riga as a Gateway: Reflections in Frederick W. B. Coleman’s 1923 Diary
Authors: Selga Marika 
Published: February 2023

Mr. Frederick William Backus Coleman (1874‒1947) was the first Extraordinary Envoy and Plenipotentiary Minister of the United States to the Republic of Latvia (Estonia, Lithuania) He worked in Latvia from November 1922 to October 1931. This research is based mainly on such primary sources as a diary and letters of Frederick William Backus Coleman. Through the prism of visitors mentioned in the diary, the author attempts to gain insight into the activities of the U.S. Legation in Riga in 1923 and subsequently ascertain the U.S. foreign policy. Most of Coleman’s visitors highlight a divergence of views on how to proceed with Soviet Russia and on cooperation with Europe. During these times, the Legation became a repository of knowledge on Soviet Union.
Effects of Isolated or Enriched Housing at Adolescence Upon Ethanol Intake and Anxiety Responses, In Rats Exposed to Prenatal Ethanol
Authors: Di Doi Paula , Fernández Macarena Soledad , Haeger Soto Paola , Pautassi Ricardo 
Published: February 2023

Abstract
Prenatal alcohol exposure (PAE) is highly prevalent worldwide, and can affect alcohol intake and anxiety responses in the offspring. It is still relatively unknown how PAE interacts with stress exposure at adolescence, and there is a scarcity of treatments to reduce the impact of PAE. The present study assessed alcohol (ethanol) intake and anxiety responses after PAE and tested the modulation of these responses by different housing conditions during early adolescence. Pregnant dams were exposed for 22 hours/day, from gestational day 0, throughout pregnancy, and until postnatal day 7 (PD 7), to a single bottle of 10% ethanol that was mixed in tap water and sucralose (EtOH Group), or to a single bottle of tap water and sucralose (CTRL Group). During PDs 21-42 the offspring was exposed to standard pair housing, isolated housing or enriched housing. Immediately after, they were pair-housed and tested for ethanol intake in 24-hour access, intermittent 2-bottle choice sessions conducted over 4 weeks, and for anxiety responses in the light-dark box test. The EtOH offspring exhibited heightened anxiety (i.e., greater avoidance of the white area of the light-dark box) at PD21, when compared to control (CTRL) rats. Isolated housing induced greater avoidance of the white area, when compared to standard or enriched housing, on PDs 42 and 70. There were no significant EtOH versus CTRL differences in relative (i.e., percent preference vs. water) ethanol intake, yet overall fluid intake and absolute (g/kg) ethanol intake were significantly lower in EtOH versus CTRL rats. Enriched housing during adolescence had a suppressing effect upon absolute ethanol intake during the first week of testing, an effect more noticeable in CTRL than in PAE rats. The present study indicates that PAE or isolated housing is associated with an anxiety-like phenotype. The protracted PAE protocol here employed caused a generalized reduction of intake behaviours. Environmental enrichment was associated with a subtle, yet significant, reduction in absolute ethanol intake.