bluuebunny/crossref_metadata_2025_split huggingface dataset:
Correlation of sdLDL-C with cardiometabolic risk indices in women with subclinical hypothyroidism– A cross-sectional study
Authors: Rani V. Samyuktha , M. S. Rukmini , M. Nandini , Prabhu K. Ashok 
Published: September 2023

Introduction and Aim: Subclinical hypothyroidism (SCH) characterised by normal free thyroxine (FT4)­­, “free triiodothyronine (FT3)”, and raised serum TSH, is an early stage of mild thyroid hormone deficiency. A change in the lipid profile most often observed in SCH is mainly caused by increased serum levels of Triglycerides (TG), total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C), whereas high-density lipoprotein cholesterol (HDL-C) levels can be normal or elevated. Studies on small dense Low Density Lipoprotein – Cholesterol (sdLDL-C), associated with CVD risk are few. The aim of this study was to estimate serum sdLDL-C and find its correlation with thyroid profile (FT4 and TSH) and cardiometabolic risk indicators in female subjects with subclinical hypothyroidism.

Materials and Methods: The study had 112 female participants in total. After screening, subjects were divided into two groups. Control group (euthyroid) and study group (SCH). Age, TSH, FT4, TC, TG, HDL-C, LDL-C, sdLDL-C & Lipid ratios “(TC/HDL-C, LDL-C/HDL-C”, “Log TG/ HDL-C)” were examined and compared between the two groups.

Results: The correlation of sdLDL-C with TSH, FT4, lipid parameters & lipid ratios were studied. TG, TC, HDL-C, and LDL-C were not clinically significant. While sdLDL-C and lipid ratios had a statistical decrease, it was not clinically significant. A highly significant negative association between sdLDL-C, other lipid parameters, except HDL-C, lipid ratios are observed in the study group.

Conclusion: As anticipated, the current investigation did not demonstrate any statistically significant improvement in the sdLDL-C as a better predictor of CVD risk. No apparent lipid abnormalities were also seen in women, in the age group of 20-40 years as observed in the correlation studies. However, measurement of AIP along with FT4 would make a better assessment of CVD risk.
Tisagenlecleucel (Kymriah)
Authors: CADTH  
Published: September 2023

CADTH recommends that Kymriah be reimbursed by public drug plans for the treatment of adults with relapsed or refractory follicular lymphoma (FL) if certain conditions are met.
Kymriah should only be covered to treat adults who have grade 1, 2, or 3a FL whose disease did not respond to a second or later line of treatment, returned within 6 months after 2 or more treatments, or returned after an autologous stem cell transplant (SCT).
Kymriah should only be reimbursed for patients who have not already received a chimeric antigen receptor (CAR) T-cell therapy, are in relatively good health, and the cost of Kymriah is reduced. Kymriah should be prescribed and administered by clinicians with expertise in blood cancers in a hospital setting with adequate resources to treat patients and manage side effects.
Spatiotemporal variability in pH and carbonate parameters on the Canadian Atlantic continental shelf between 2014 and 2022
Authors: Gibb Olivia , Cyr Frédéric , Azetsu-Scott Kumiko , Chassé Joël , Childs Darlene , Gabriel Carrie-Ellen , Galbraith Peter S. , Maillet Gary , Pepin Pierre , Punshon Stephen , Starr Michel 
Published: September 2023

Abstract. The Atlantic Zone Monitoring Program (AZMP) was established by Fisheries and Oceans Canada (DFO) in 1998 with the aim of monitoring physical and biological ocean conditions in Atlantic Canada in support of fisheries management.
Since 2014, at least two of the carbonate parameters (pH; total alkalinity, TA; and dissolved inorganic carbon, DIC) have also been systematically measured as part of the AZMP, enabling the calculation of derived parameters (e.g., carbonate saturation states, Ω, and partial pressure of CO2, pCO2).
The present study gives an overview of the spatiotemporal variability in these parameters between 2014 and 2022.
Results show that the variability in the carbonate system reflects changes in both physical (e.g., temperature and salinity) and biological (e.g., plankton photosynthesis and respiration) parameters.
For example, most of the region undergoes a seasonal warming and freshening.
While the former will tend to increase Ω, the latter will decrease both TA and Ω.
Spring and summer plankton blooms decrease DIC near the surface and then remineralize and increase DIC at depth in the fall.
The lowest pCO2 values (down to ∼ 200 µatm) are located in the cold coastal Labrador Current, whereas the highest values (>1500 µatm) are found in the fresh waters of the Gulf of St. Lawrence and the St. Lawrence Estuary.
The latter is also host to the lowest pH values of the zone (7.48 in the fall of 2022).
Finally, most of the bottom waters of the Gulf of St. Lawrence (>90 %) are undersaturated with respect to aragonite (Ωarg<1).
In addition to providing a baseline of carbonate parameters for the Atlantic Zone as a whole, this comprehensive overview is a necessary and useful contribution for the modelling community and for more in-depth studies.
The full dataset of measured and derived parameters is available from the Federated Research Data Repository: https://doi.org/10.20383/102.0673 (Cyr et al., 2022a).
TEACHING ENGLISH GRAMMAR BY USING DEDUCTIVE METHOD THROUGH GROUP WORK
Authors: Merla Merla 
Published: September 2023

The objective of this research is undertaken to see whether the deductive method in teaching English grammar by using the group work technique has a positive effect on the academic achievement of the students of Dual System Class B at Politeknik ATI Makassar, expecially for students. Using deductive method with the help of group work played a positive role in improving the academic achievement of students who studying English at Dual System class. This method with the help of group work has improved the score Pre-test (60.9000) and Post-test (86.2000). This method also can improve students’ grammar in use, motivate students in learning grammar and as an effective method in teaching grammar. This research as also change what people think that deductive method often make the learners’ role rather passive as much of the attention is only focused on the teacher explaining the rules and showing the examples.
Cartografia social e os mapas mentais: a importância das abordagens qualitativas na educação geográfica.
Authors: Silva Edilson dos Santos 
Published: September 2023

Diante de uma sociedade que se mostra cada vez mais complexa e do espaço geográfico progressivamente mais globalizado, as pesquisas qualitativas assumem cada vez mais importância. A partir da década de 1990, a cartografia social emerge fruto da emergência em relacionar a produção de mapas com a dimensão social. O presente trabalho tem como objetivo analisar a relevância da metodologia da cartografia social como meio para inserir a abordagem qualitativa ao processo de mapeamento, através da metodologia dos mapas mentais. Fundamentado em um estudo bibliográfico, procuramos discutir se a abordagem qualitativa na cartografia, materializada através dos mapas mentais, é capaz de contemplar as vivências dos estudantes e ressignificar a função dos mapas na educação geográfica? A abordagem qualitativa nos mostra que é possível e socialmente relevante inserir aos mapas os elementos subjetivos do espaço, através dos princípios da cartografia social mediados pelo uso dos mapas mentais, o processo de mapeamento passa a ser democrático, participativo e sobretudo uma construção social, abrindo caminho para que as diversas realidades sejam representadas, problematizadas e questionadas.
Palavras-chave: Pesquisa qualitativa; Cartografia social; Mapa mental.
Relato de prática pedagógica: educação especial na pandemia
Authors: De Campos Sheila Garbulha Tunuchi 
Published: September 2023

A proposta, aqui, é a de apresentar o relato de uma experiência sobre práticas pedagógicas na educação especial vivida durante o período da pandemia da covid-19, especialmente no recorte temporal de 2020 a 2021. O intuito é compartilhar sobre as atividades realizadas no ensino não presencial no âmbito escolar, levando-nos a olhar para uma reﬂexão-na-prática pedagógica do ensino especializado, considerando a mediação entre a professora especialista em deﬁciência intelectual atuante na sala de recursos e duas alunas da educação especial inseridas na educação infantil (pré-escolar), ambas com 5 anos de idade. A unidade escolar de ensino localiza-se na zona rural do município de Porto Feliz, interior do estado de São Paulo. Compartilharei da experiência em meio ao tempo da modalidade do ensino não presencial, utilizando como referência dois projetos realizados para atendimento da demanda da pré-escola e levando ainda em consideração o quadro da diﬁculdade de aprendizagem das alunas. Sob o olhar do reﬂetir-na-prática acerca das atividades planejadas, que pudessem atingir este público, os meios utilizados envolveram o uso de recursos virtuais como a internet, vídeo chamada por aplicativo do celular e conversas pelo WhatsApp, ligações telefônicas e envio de link com vídeos explicativos produzidos pela professora, bem como materiais concretos organizados para realizar as tarefas em casa. Os projetos pedagógicos “Sala Viajante” e “Mochila Viajante” tiveram o viés psicopedagógico e os materiais foram projetados para a realização de atividades lúdicas e motoras e para reconhecimento das letras e dos números. Os objetivos versaram em: proporcionar o acesso aos materiais e às atividades parecidos com aqueles existentes no ambiente físico de uma sala de recursos; proporcionar atividades com materiais direcionados e em formato para o nível-concreto de compreensão das alunas; e criar um momento prazeroso para a aquisição da aprendizagem com vínculo afetivo entre estudante e família. As atividades e materiais foram projetados de forma que a família tivesse a preocupação somente em acompanhar e mediar a produção junto à criança, uma vez que a localização de suas residências na zona rural do município as impediam em adquirir materiais e outros objetos para a realização das tarefas. Como análise e observação sobre os resultados alcançados com ambos os projetos aplicados, houve um retorno positivo com devolutivas das atividades por meio de registros por fotos e vídeos, encaminhados à professora. As famílias pontuaram o fato de possuírem os materiais necessários para cada tarefa ajudou no processo de construção, produção e participação da criança, considerando as necessidades pontuais em relação à região da zona rural, bem como o quadro de diﬁculdade de aprendizagem, devido às questões intelectuais e motoras. Sendo assim, os projetos pedagógicos direcionados ao público-alvo foi produtivo e atendeu às demandas do momento do ensino não presencial escolar.
Realidade aumentada no ensino regular: aplicação nos anos finais
Authors: Fregapani Daniel Diniz , Roberto José Carlos Alves , Pinto Junior José Roberto Lira 
Published: September 2023

O objeto de análise desse artigo são as aplicações da tecnologia RA- realidade aumentada e sua implantação no ensino regular anos finais. O trabalho está subdividido, além desse resumo, em 6 (seis) partes: introdução, fundamentação teórica, metodologia, resultados, conclusão e bibliografia. A origem do estudo da aplicação do RA no ensino regular em materiais paradidáticos veio de necessidade de implementar a melhor adaptação de experiências originalmente produzidas em cards, dentro de trilhas educacionais, qualificando o público alvo docentes e discentes para utilização dessa tecnologia de acordo com os conteúdos previstos na BNCC – Base Nacional Comum Curricular por série, no ensino regular segmento anos finais. A empresa produtora dos materiais paradidáticos de referência desse artigo é a empresa Lion Mídia e Entretenimento LTDA - https://www.lionstudios.com.br/ situada no endereço AV Efigênio Salles N. 2300 Sala 210 Condomínio Boulevard Mundi na cidade de Manaus /AM. A questão a ser solucionada identificada foi como adaptar o uso de experiência isoladas em RA, produzidas originalmente em Cards, para sua utilização com enquadramento dentro da BNCC? Qual seria a melhor forma de adaptar essa tecnologia para sua utilização, qual seria a melhor forma de acesso, como poderia ser inserido de forma coletiva dentro da educação básica? Objetivo desse artigo foi apresentar a solução desenvolvida para nivelar o acesso à conteúdos previamente desenvolvidos em tecnologia RA, para sua aplicação em escala, utilizando plataforma com funcionamento off-line como meio de acesso universal, tornando factível reduzir eventuais diferenciações de aprendizagem em alunos da mesma faixa etária, mesmo momento educacional proporcionando maior isonomia do meio educacional no acesso à tecnologia, acesso aos conteúdos ministrados, permitindo através da experimentação com atividades práticas, estimular cada aluno a ser protagonista de seu processo de aprendizagem.
Impact of Financial Inclusion on Women Entrepreneurs in India: An Empirical Study
Authors: Rani Vosuri Sandya , Sundaram Natarajan 
Published: September 2023

Purpose: Researchers, practitioners, government leaders, as well as other stakeholders keep expressing a great deal of interest mostly in the close connection between economic inclusion with women having entrepreneurship on a both national and international scale.

Theoretical framework: The fundamental objective is still to increase women's access to finance so they can engage in entrepreneurship. The latest evidence exploring the connection between women's entrepreneurship as well as financial inclusion has generated an assortment of findings that are more conventional than reality.

Design/methodology/approach: This study looked into how financial inclusion affected the functioning of women-owned enterprises in Vellore, Tamilnadu, India. One thousand two thousand seventy-four (1,274) women-owned Small and medium enterprises, Small and Medium Businesses (MSMEs) registered with MSME made up the participants in this investigation, as well as three hundred fifty-seven (357) MSMEs being chosen as such sample size.

Findings: The research used structured questionnaires and in-person interviews to collect data. Multiple Regression (Ordinary Least Square Estimate), as well as Pearson Product Moment Correlation Coefficient, were used to examine the data. Findings indicated that the efficiency of women-owned enterprises is positively and significantly impacted by financial inclusion.

Research, Practical & Social implications: In hopes of reducing the gender disparity in financial intermediation, it is advised that the administration put laws and legislative regulations in place.

Originality/value: Recognizing the crucial role that women-owned businesses play in the country's economic expansion and continue to increase gender diversity to foster an atmosphere of innovation.
The Asymmetric Effects of Foreign Direct Investment Inflow on Economic Growth: Fresh Evidence from Somalia
Authors: Mohamed Abdulrazak Nur , Abdulle Abdikani Yusuf Abdulle 
Published: September 2023

Purposes: Although there has been some progress since the 2012 establishment of the Federal Government Somalia, Foreign direct investment is the one of critical engines in economic growth. The latest value of foreign direct investment for 2021 was 5.97% of GDP, comparison of previous years to 2020 was 6.74% of GDP in Somalia. This paper aims to investigate the asymmetric effects of foreign direct investment (FDI) inflow on economic growth in Somalia from 1977-2021. In addition to FDI, inflation, gross capital formation, and trade openness are used as control variables to examine their influence on economic growth.

Design/Methodology/approach: This research employs the nonlinear autoregressive distributed lag (NARDL) technique.

Finding: The findings reveal that a positive shock in FDI positively influences Somalia's economic growth, while a negative FDI has a negative impact. The Wald test establishes the asymmetric effect of FDI on economic growth in both the short and long run. Moreover, trade openness and inflation rate significantly reduce the pace of economic growth in both the long and short run. However, gross capital formation only boosts economic growth in the long run.

Research limitations/ implications: although Somali faced a lot of challenges including civil war, terrorists, macroeconomics instability, poor infrastructure, and corruptions are not considered owing to data availability. Policy implications: firstly, increase revenue through tax reforms and anti-corruption measures. Secondly, initiatives policies that help public finance investments and reduce trade barriers. Finally, maintain macroeconomic stability of inflation, and exchange rates, can help reduce the negative impact on economic growth improve the investment climate and Somalia’s image abroad.
Contribution of the Scientific Production of Higher Education Teachers to the Improvement of the Educational Quality of the Universidad Nacional Intercultural Fabiola Salazar Leguía de Bagua, Northern Peru
Authors: Morales Eli Morales , Araníbar-Araníbar Marcelino Jorge , Chayña Euclides Ticona , Reategui-Inga Manuel 
Published: September 2023

Objective: The objective of this study is to analyze the scientific contribution of the regular teachers of the Universidad Nacional Intercultural Fabiola Salazar Leguía de Bagua (UNIFSLB) since their first linkage.

Method: A review of databases (Latindex 2.0, Scielo, Web of Science and Scopus), as well as relevant management documents was carried out. Likewise, the annual growth rate and the behavior of the promotion and dissemination of science through its journals hosted in OJS were evaluated. Data analysis was carried out using Minitab 19.1 and VOSviewer programs.

Results: They reveal a remarkable annual growth rate of 31.12%, with a scientific production of 115 articles. In 2022, publications in Scopus and Scielo stand out with 32 articles and 2 in Scielo, respectively. The dissemination of scientific production is mainly through the scientific and academic journals "Dékamu Agropec" with 53 publications and "Manguare" with 32. However, the presence of publications related to interculturality is limited (5 in Web of Science and 2 in Scopus).

Conclusions: The minimal number of publications could be due to insufficient economic allocation for research. Therefore, it is necessary to implement policies that promote the valuation of ancestral knowledge and that this is validated through the generation of knowledge in accordance with the lines of research. This, in turn, is associated with the low visibility of keywords related to specific topics.
Analysis of the advantages of applying VR to education
Authors: Xu Shuo , Lu Ran , Liu Peiyu 
Published: September 2023

In 2021, the concept of Metaverse had become popular globally. VR, as the carrier and business form of the development of the Metaverse, entered the public's perspective; it has been widely applied in high-end technological fields such as new media, aerospace, and military so far. In the future, it will be widely applied as an advanced technological means in the field of education, promoting the digitization of teaching processes. Therefore, this paper analyzes the advantages of applying VR to education in order to enrich teaching methods and create a new educational model.
Trade Openness, Digital Economy and Spatial Spillover ---An empirical study based on China's provincial panel data
Authors: Guo Xiaoming , Zheng Qie 
Published: September 2023

Based on panel data of 31 provinces in China from year 2010 to 2020, this paper constructs a provincial digital economy evaluation index system to measure the digital economy development. Under the framework of static and dynamic spatial panel models, this paper empirically studies the spatial effects of China's provincial trade openness on the development of digital economy. The results show that China's provincial trade openness has obvious positive and spatial effects on the development of digital economy, and the local trade openness has a sustainable driving effect on its own digital development, but not sustainable for the neighboring region. Moreover, the influence of the eastern regional trade openness on the digital economy shows a spatial diffusion pattern in the short and long term, while that of the central and western regions shows a spatial siphon effect pattern.
The Impact of the Extraterritorial Application of American Law on China and the Response to it
Authors: Li Qiwen 
Published: September 2023

The extraterritorial application of American law has a long history of development, which has developed from the original firm territorialism to the " effect principle". Today, under the banner of the "America First" principle, the U.S. continues to expand the range of the extraterritorial application of its laws by expanding the "connection point", to achieve its political objectives, putting on a“legitimacy” cloak. After continuous development, it has been characterized by legal hegemony, extensive connection points, systematic operation, the politicization of applicable objects, and low predictability. The improper extraterritorial application of American law has caused many adverse effects on China, and China has actively responded to them through national legislation, regional cooperation, and enterprise compliance and legal remedy. However, these measures are still insufficient to eliminate all the adverse effects and to safeguard the legitimate rights and interests of our country. Therefore, China should also further improve it by formulating and revising relevant laws and regulations, improving working mechanisms, setting up compensation mechanisms and strengthening foreign-related rule of law talents, making full use of international and domestic laws to effectively curb the improper extraterritorial application of American law, and protect China's overseas interests.
The Response Characteristics of Sugarcane Yield, ET and WUE to Meteorological Drought Based on DSSAT-Canegro Model in Lai-bin, China
Authors: Wang Tingyan , Yang Yunchuan , Zhang Huiya , Wang Weiquan , Gan Rumin , Liang Liqing , Li Zongheng , Wei Changzheng 
Published: September 2023

Crop water use efficiency is an important indicator of the scientific and rational nature of agricultural water use. Studying the response characteristics of sugarcane yield accumulation and water use efficiency to meteorological drought scenarios is a key scientific issue to promote smart management and sustainable development of China's sugarcane industry. In this paper, based on SPEI index, different meteorological drought scenarios were set and the DSSAT-Canegro model was used to simulate the response mechanisms of sugarcane yield accumulation and canopy evapotranspiration to irrigation regime scenarios under different meteorological drought scenarios. Furtherly, in this study, the total on-farm water use efficiency (WUEg), field water use efficiency (WP), true irrigation water use efficiency (WUEti), and irrigation water use efficiency (WUEi) of sugarcane in the study area were evaluated quantitatively to screen the optimal irrigation regime. Specific studies have shown that the stem extension stage is the most sensitive growth stage for sugarcane response to irrigation. Soil evapotranspiration and crop transpiration in sugarcane fields in Laibin varied with irrigation quotas, and that reducing soil evapotranspiration could improve sugarcane water use efficiency. In meteorological drought scenarios with longer and more intense droughts, irrigation has a stronger stimulating effect on sugarcane growth and is more favourable to its yield accumulation.The correlations between WUEg index and WP, WUEi) and WUEti indicators of sugarcane in the study area were all significant, which can be used as key analytical indicators for the optimization of sugarcane irrigation regimes in Laibin. The results of this study can provide important scientific support for the accurate quantification of water demand and consumption of sugarcane in southern China and their coupled and coordinated intelligent management.