bluuebunny/crossref_metadata_2025_split huggingface dataset:
Філософська складова фамілістичних досліджень
Authors: Шаталович Олександр , Шаталович Інна 
Published: March 2023

Актуальність статті викликана поверненням теми сім’ї у коло філософських досліджень. У ХІХ-ХХ століттях тема сім'ї, не зовсім заслужено, як на думку авторів статті, була витіснена з філософського дослідницького поля і практично монополізована соціологією, психологією і демографією. Останні десятиліття відбувається відновлення міждисциплінарного балансу, що підтверджується неухильним зростанням філософських досліджень сім'ї. Метою статті є систематизація і експлікація філософської складової фамілістичних досліджень, яка активно розгортається у сучасному науковому просторі. У ході дослідження були отримані такі результати. Кожна з наук (таких як соціологія, психологія, демографія та ін.), яка відокремлено досліджувала феномен сім'ї, виявилася не в змозі охопити його в повноті, що викликало у дослідників (зокрема, А. Антонов, В. Медков, Є. Рашковський) пропозицію про міждисциплінарний синтез наук про сім'ю. Реалізація зазначеного синтезу пов'язана, за своєю суттю, з вирішенням філософської задачі сучасного розгляду сімейної форми людського буття з найбільш загальної точки зору, або в перспективі, з формуванням нового філософського підрозділу – філософії сім'ї. У статті проаналізовано соціально-філософський, історико-філософський, гендерно-антропологічний, етико-аксіологічний, екзистенціально-феноменологічний, метафізичний, діалектичний, семіотико-лінгвистичний, філософсько-релігійний, філософсько-психологічний, філософсько-педагогічний, філософсько-культурологічний, системно-синергетичний та комунікативний напрямки. За допомогою даних підходів сім'я розглядається в якості концепту, поняття, універсалії, ідеалу, цінності, норми, екзистенціалу, феномену. Продуктивними для дослідження сім'ї є також поняття системності, самоорганізації, комунікації. Автори дійшли до наступних висновків. Хоча соціально-філософський напрямок є найбільш розвиненим, проте перспективними для подальшої розробки є метафізичний та етико-аксіологічний напрямки. До ключових тем виділених напрямків належать: метафізична значимість сім'ї, її онтологічні підстави і проблема визначення, а також проблема ідеалу християнської сім'ї та конфлікту ідеалів сімейного та особистого буття. Подальше виявлення філософських вимірів сім'ї дозволить поряд з визнаними в науковому співтоваристві дисциплінами, такими як «соціологія сім'ї», «психологія сім'ї» або «демографія сім’ї» сформувати актуальний для сьогодення напрям «філософія сім'ї».
Modéliser la prise de Constantinople (1204) •
Authors: Grévin Benoît 
Published: March 2023

AbstractThe fictional letters on the capture of Constantinople in 1204 and its aftermath written by the professor of rhetoric Boncompagno da Signa for his treatise Boncompagnus (1215/1226) form a prime document for examining the relationship between real and fictional correspondence in the Middle Ages. By comparing their content, structure, and rhetorical devices with those of a set of documents written on the same theme, including the letter sent by Baldwin of Flanders to Pope Innocent III to report on the events of 1204, it is possible to identify the way in which Boncompagno drew inspiration from this official letter to compose his model letter, and what differentiates them. This comparative analysis allows us not only to deepen our knowledge of the processes of the fictionalisation of history at work in Italy in the thirteenth century, but also to take a different look at the rhetoric of official letters or other texts (poems, stories) relating the same events.
Effects of early mental state changes on physical functions in elderly patients with a history of falls
Authors: Cui Yao , Liu Bo , Qin Ming-Zhao , Liu Qian , Ye Hui 
Published: March 2023

Abstract
Background: Fear of falling is a potential consequence of falling in older adults. Whether such fall-related psychological concerns in turn affect physical function? Especially those who have a history of falling but have not been diagnosed with anxiety, depression or both. This study aimed to clarify the effects of early psychological changes on the physical function of order patients.
Methods: The 111 participants with falling history were divided into the poor physical function (PPF) group with SPPB≤9 and the good physical function (GPF) group with SPPB>10. Their physical function was assessed through 4-meter gait speed (4MGS), five times sit-to-stand test (FTSST), grip strength, and Timed Up and Go tests TUGT. Their mental state was assessed by the self-rating anxiety/depression scale (SAS/SDS).
Results: (1) SAS/SDS scores were negatively correlated with the SPPB score, gait speed, and maximum grip strength (males). (2) Multivariate logistic regression analysis showed that the SPPB score was subject to such independent influence factors: cerebrovascular disease (OR =15.615; P =0.001), normal ratio of grip strength (OR =0.046; P =0.008), TUGT (OR =1.671; P <0.001), and SDS score (OR =1.155; P =0.005). (3) The area under the ROC curve was 0.699 (0.601, 0.797) for SAS score, with a sensitivity of 0.776 and a specificity of 0.547; the AUC was 0.694 (0.596, 0.792) for SDS score, with a sensitivity of 0.586 and a specificity of 0.755.
Conclusions: This study showed that the higher SAS/SDS scores corresponded to poorer physical performance. SAS/SDS scores were to some extent predictive of physical function among older adults with a history of falls.
On the bumpy road to recovery: resilience of transit ridership during COVID-19 in 15 European cities
Authors: Manout Ouassim , Bouzouina Louafi , Kourtit Karima , Nijkamp Peter 
Published: March 2023

Abstract
COVID-19 had a dramatic impact on the use of transit. Most European cities report a decline in transit use during 2020 and 2021. Nevertheless, not all cities report similar decline patterns or comparable resilience paths. We investigate the resilience patterns of transit use during 2020 and 2021 in 15 European cities from 11 different countries using clustering and regression analysis of data from Google Mobility Reports. Results highlight the variety of resilience patterns of transit use in these 15 cities. These patterns vary in time and space. Transit use in some cities recovered faster and more significantly than in others. Findings also suggest that changes in retail and recreational routines have the highest impact on the resilience of transit use in most cities. Changes in workplace routines are also important, but to a lesser degree. The impact of policy stringency on transit use is significant, but less consistent between the 15 cities.
JEL classification: 40, 41, 48
A Hardware Prototype Fuzzy Logic based Automatic Accident Detection system in Vehicular Adhoc Network
Authors: bhanja urmila , Mohanty Anita , Mahapatra Sudipta 
Published: March 2023

Abstract

Traffic jams and accidents with increasing number of vehicles on the road cause significant social and financial losses. Minor accidents on the road are handled by locals and other drivers. However, attention must be paid to the serious accidents that happen more frequently. Hence, an intelligent accident detection system is necessary to detect accident and save the life of injured. Now-a-days, vehicular ad hoc network (VANET) has been used significantly to solve the issue.
In this work, we have developed a prototype hardware VANET model for detecting accidents using fuzzy logic controller (FLC) or fuzzy logic decision support. The proposed model detects accidents and sends the messages to a central server through a low range radio (LoRa) transceiver network. The server after receiving the message from a vehicle estimates the shortest path using Dijkstra’s algorithm and send messages to a nearby ambulance to take the victim to a nearby hospital. Ambulance is also a node in the proposed VANET model.
A new set of metrics to quantify the colonization potential of riverscapes by wind-dispersed plant species
Authors: Wagner Thomas C. , Wöllner Romy 
Published: March 2023

Abstract
Quantifying the potential of a braided riverscape to be colonized by a plant species is important for assessing the ecological state of the river and provides an important basis for nature conservation planning and the implementation of restoration measures. Common landscape and river connectivity indices are largely unsuitable for describing the situation for the mostly wind-dispersed plant species. We aim to provide a set of comparable metrics that allows the quantification of the colonization potential of riverscapes at the patch and riverscape level. We define and describe a set of cell-based, spatially explicit measures that can easily be implemented. We demonstrate their application using two typical plant species and three riverscapes with different habitat configurations as examples. Our metrics consider shape, size and the spatial configuration of habitat patches, along with the dispersal characteristics of the respective species. The metrics provide a linear, balanced, and realistic representation of the colonization potential at the cell, patch, and riverscape levels. The results are comparable between different riverscapes and species and can easily be extended and used for further modeling. The metrics provide a valuable tool for the planning and evaluation of conservation, restoration, and reintroduction measures and close the gap between simple habitat availability analyses and large-scale terrestrial connectivity indices.
Unilateral adrenalectomy for a drug-resistant bilateral primary aldosteronism with heart failure: pathophysiology and surgical indication
Authors: Hoshi Seiji , Onagi Akifumi , Tanji Ryo , Honda-Takinami Ruriko , Matsuoka Kanako , Hata Junya , Sato Yuichi , Akaihata Hidenori , Kataoka Masao , Ogawa Soichiro , Kojima Yoshiyuki 
Published: March 2023

Abstract
Background: Patients with bilateral primary aldosteronism (PA) generally are treated with antihypertensive drugs, but optimal treatment for patients with complications due to refractory hypertension has not been established. In this report, we present a case with bilateral PA who presented with persistent hypertension, despite treatment with 6 drugs, and left-dominant heart failure, which was improved after unilateral adrenalectomy.
Case presentation: A 61-year-old man was admitted to our hospital because of severe left-dominant heart failure. His heart rhythm was atrial fibrillation and the left ventricle was diffusely hypertrophic and hypokinetic. Coronary arteries were normal on coronary arteriogram. Primary aldosteronism was suspected based on severe hypokalemia (2.5 mEq/L) and plasma aldosterone concentration (PAC; 1,410 pg/mL). Although computed tomography (CT) showed a single left cortical nodule, adrenal vein sampling (AVS) indicated bilateral PA. Early in the case, heart failure and hyperkalemia in this patient were improved by treatment with a combination of 6 antihypertensive drugs (spironolactone 25 mg/day, eplerenone 100 mg/day, azosemide 60 mg/day, tolvaptan 7.5 mg/day, enalapril 5 mg/day, and bisoprolol fumarate 10 mg/day); however, heart failure relapsed after four months of treatment. We hypothesized that hypertension caused by excess aldosterone was inducing the patient’s heart failure. In order to reduce aldosterone secretory tissue, a laparoscopic adrenalectomy was performed for the left adrenal gland, given the higher level of aldosterone from the left gland compared to the right. Following surgery, the patient’s heart failure was successfully controlled despite the persistence of high PAC. Treatment with anti-hypertensive medications was reduced to two drugs (eplerenone 100 mg/day and bisoprolol fumarate 10 mg/day). In order to elucidate the mechanism of drug resistance, immunohistochemistry (IHC) and real time-polymerase chain reaction (RT-PCR) assays were performed to assess the expression of steroidogenic factor 1 (SF-1), a regulator of steroid synthesis in adrenal tissue. IHC and RT-PCR demonstrated that the expression of SF-1 in this patient (at both the protein and mRNA levels) was higher than that observed in unilateral PA cases that showed good responsivity to drug treatment.
Conclusions: Unilateral adrenalectomy to reduce aldosterone secretory tissue may be useful for patients with drug-refractory, bilateral PA. Elevated expression of SF-1 may be involved in drug resistance in PA.
Association of PM 2.5 level with pediatric patient visits for respiratory diseases in Bangkok, Thailand
Authors: Sittichai Phopthanaphon , Supapueng Orawan , Udomittipong Kanokporn , Tovichien Prakarn 
Published: March 2023

Abstract
Background
High levels of PM2.5 in Bangkok are concerned. We aimed to study the association of PM2.5 level with pediatric patient visits for respiratory diseases.
Methods
This retrospective study collected hospital visits of children less than 18 years for respiratory diseases and PM2.5 level during 2018–2020. Number of hospital visits with diagnoses of upper respiratory infections (URIs), acute bronchitis, acute bronchiolitis, pneumonia and asthmatic exacerbation were collected. We analyzed the association of weekly average of PM2.5 level with pediatric patient visits for respiratory diseases using a time-series analysis and a negative binomial model. We adjusted year, seasons, number of influenza and respiratory syncytial virus (RSV) cases as confounders.
Results
We found a significant association between weekly average of PM2.5 level and patient visits for URIs and acute bronchitis in children less than 2 years and asthmatic exacerbation in children less than 5 years. During winter, when weekly average of PM2.5 level was above 55 µg/m3, there was 40% increase in URIs cases and 80% increase in acute bronchitis cases in children less than 2 years.
Conclusions
High level of PM2.5 was associated with number of pediatric outpatients with URI, acute bronchitis and asthmatic exacerbation. Younger age group had more significant association.
The Efficacy of Oxytocin Gel in Postmenopausal Women with Vaginal Atrophy: An Updated Systematic Review and Meta-Analysis
Authors: Farahat Ramadan Abdelmoez , Salamah Hazem Mohamed , Mahmoud Abdelrahman , Hamouda Esraa , Hashemy Mahmoud , Hamouda Heba , Samir Ali , Chenfouh Imane , Marey Ahmed , Awad Dina M. , Farag Elsayed , Abd-Elgawad Mohamed , Eldesouky Elsayed 
Published: March 2023

Abstract
Background
Genitourinary syndrome of menopause (GSM) is a common disturbing issue in the postmenopausal period. Unlike vasomotor symptoms, it has a progressive trend. Our study aims to evaluate the efficacy and safety of oxytocin gel versus placebo gel in postmenopausal women with GSM.
Methods
A systematic review and meta-analysis synthesizing randomized controlled trials (RCTs) from Web of Science, SCOPUS, PubMed, and Cochrane Central Register of Controlled Trials databases on January 18, 2023. We used the risk ratio (RR) for dichotomous outcomes and mean difference (MD) for continuous outcomes; both presented with the corresponding 95% confidence interval (CI).
Results
Seven studies with 631 patients were included. Regarding the maturation index, there was a statistically insignificant increase in the oxytocin arm (MD= 12.34, 95% CI (-12.52-37.19), P= 0.33). Vaginal atrophy showed a statistically significant reduction in the oxytocin group (RR= 0.32, 95% CI (0.23-0.10), P< 0.00001). For dyspareunia, vaginal pH as well as histological evaluation of vaginal atrophy, there was a statistically insignificant difference between the two groups (RR= 1.02, 95% CI (0.82 -1.27), P= 0.84), (MD= -0.74, 95% CI (-1.58-0.10), P= 0.08) and (MD= -0.38, 95% CI (-0.82-0.06), P= 0.09) respectively. There was no significant difference in the safety profile between the two groups as measured by endometrial thickness (MD= 0.00, 95% CI (-0.23-0.23), P= 0.99).
Conclusions
Although oxytocin has been proposed as a viable alternative to estrogen in the treatment of GSM, our findings show the opposite. Larger, high-quality RCTs are needed to confirm or refute our results.
PROSPERO number
CRD42022334357.
Data-Driven Control of Neuronal Networks with Population-Level Measurement
Authors: Vu Minh , Singhal Bharat , Zeng Shen , Li Jr-Shin 
Published: March 2023

Abstract
Controlling complex networks of nonlinear neurons is an important problem pertinent to various applications in engineering and natural sciences. While in recent years the control of neural populations with comprehensive biophysical models or simplified models, e.g., phase models, has seen notable advances, learning appropriate controls directly from data without any model assumptions remains a challenging and less developed area of research. In this paper, we address this problem by leveraging the network’s local dynamics to iteratively learn an appropriate control without constructing a global model of the system. The proposed technique can effectively regulate synchrony in a neuronal network using only one input and one noisy population-level output measurement. We provide a theoretical analysis of our approach and illustrate its robustness to system variations and its generalizability to accommodate various physical constraints, such as charge-balanced inputs.
Full Orbital Phase Curve of KELT-1b using TESS observations
Authors: Eftekhar Mohammad 
Published: March 2023

Abstract
We present our joint model for comprehensive phase curve analysis of the transiting brown dwarf KELT-1b using observations from the Transiting Exoplanet Survey Satellite (TESS). We developed a full model of the phase curve over the orbit of a star-planet system, which includes primary transit, secondary eclipse, thermal emission, reflection, ellipsoidal tidal distortion, and Doppler beaming. All of these are jointly fitted simultaneously to obtain the parameters from the data sets. After taking out the instrumental systematic noise, we reliably detect the secondary eclipse with a depth of 383+36−24 ppm. Its hotspot is located east of the substellar point, demonstrating heat transport from the dayside (3005+207−191K) to the nightside (< 1491+162−145K) at the altitudes probed by TESS. Our estimated geometric albedo, Ag = 0.47+0.06−0.04, suggests that KELT-1b has a high geometric albedo. Finally, our estimated amplitude of the ellipsoidal variation and Doppler beaming signal is in agreement with the predictions of the theoretical expectations.
Evaluating the performance of a plasma dual-target test developed based on sense-antisense and dual-MGB probe technique for colorectal cancer detection
Authors: Zhao Yanteng , Wang Zhijie , Yu Qiuning , Liu Xin , Liu Xue , Dong Shuling , Lv Xianping , Bai Yu , Wang Shaochi 
Published: March 2023

Abstract
Background
Detecting colorectal cancer (CRC) via blood-based methylation tests shows good patient compliance and convenience, but some use to fail due to the low abundance of plasma cfDNA fragments. To address this issue, we designed this study to identify potential markers and enhance their performance to detect CRCs using sense-antisense and dual-MGB probe (SADMP) technique.
Methods
The study was conducted in three steps: identifying eligible methylation markers in our discovery set, developing assay using the sense-antisense and dual-MGB probe (SADMP) technique, and evaluating the test performance for CRC detection in training and validation cohorts.
Results
Findings of the discovery step indicated that adenoma and cancer samples exhibited similar methylation profiles and both had lower methylation levels than normal samples. Hypermethylated NTMT1 and MAP3K14-AS1 were recognized as the most promising candidate markers. The SADMP technique showed an ability to improve methylation signals by 2-fold than single-strand and single-MGB probe techniques. The MethyDT test, incorporating the SADMP technique, obtained an average sensitivity of 84.47% for CRC detection, higher than any single target alone, and without significant attenuation in specificity (average specificities of 91.81% for NTMT1 and 96.93% for MAP3K14-AS1 vs. 89.76% for MethyDT). For early (I-II) and late- (III-IV) stage CRC, the sensitivities were 82.61% and 88.64%, respectively. Meanwhile, the test performance was independent of patient age and gender.
Conclusion
The MethyDT test incorporating the SADMP technique exhibits a higher sensitivity to perceive methylation signals and may serve as a promising noninvasive tool for CRC detection.
Prediction of distant metastasis and specific survival prediction of small intestine cancer patients with metastasis: a population-based study
Authors: Xu Jinyi , Yao Zhiyi , Liao Guoliang , OuYang Xi , Mao Shengxun , Cao Jiaqing , Lai Bin 
Published: March 2023

Abstract
Background: Small intestine cancer (SIC) is a rarely found gastrointestinal malignancy, however early diagnosis of SIC is difficult as patients often present poor prognoses due to distant metastasis (DM) of the tumor by the time of diagnosis. Although nomograms for SIC have been developed, there are no relevant studies on the diagnosis and prognostic assessment of DM in patients with SIC.
Methods: The data of patients diagnosed with SIC between 2010 and 2015 was extracted from the Surveillance, Epidemiology and End Results (SEER) database. All patients were randomly assigned into the training and validation sets (7:3). Independent risk factors for DM in SIC patients were then determined by univariate and multifactor logistic regression analysis. In addition, independent prognostic factors for overall survival (OS) and cancer-specific survival (CSS) in patients with DM were analyzed by univariate and multifactor Cox regression analysis, respectively. We then constructed the corresponding three nomograms and assessed the clinical efficacy of the nomograms by receiver operating characteristic (ROC) curves, decision curve analysis (DCA), and calibration curves.
Result: The entire cohort consisted of 6773 SIC patients, of whom 1327 had DM at diagnosis. The results of multifactorial logistic regression analysis showed that T-stage, N-stage, tumor collaborative stage (CS) extension and histological type acted as independent risk factors for DM in patients with SIC. The results of multifactorial Cox regression analysis indicated that age, sex, histological type, N stage and tumor CS extension were independent predictors of OS; sex, histological type, N stage and tumor CS extension served as independent predictors of CSS. The results of ROC curves, DCA, calibration curves, and Kaplan-Meier (K-M) survival curves in the training and validation sets further confirmed the excellent accuracy of the three nomograms in predicting DM and prognosis in SIC patients.
Conclusion: This study constructed and validated nomograms for predicting DM in SIC patients as well as OS and CSS in patients with DM, which appear to function, as excellent tools to aid the physicians make more rational and personalized clinical decisions.