bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of acupuncture and medical training therapy on depression, anxiety, and quality of life in patients with frequent tension-type headache: A randomized controlled study
Authors: Schiller Joerg , Niederer Daniel , Kellner Tim , Eckhardt Isabelle , Egen Christoph , Zheng Wen , Korallus Christoph , Achenbach Johannes , Ranker Alexander , Sturm Christian , Vogt Lutz , Gutenbrunner Christoph , Fink Matthias G , Karst Matthias 
Published: January 2023

Objectives To compare the effects of acupuncture and medical training therapy in combination or individually with usual care on quality of life, depression, and anxiety in patients with tension-type headache. Methods In this single-center, prospective, randomized, controlled, unblinded trial, 96 adults (38.7(+/−13.3) years of age; 75 females/20 males/one dropout) with frequent episodic or chronic tension-type headache were randomized to one of four treatment groups (n = 24). The treatment groups received six weeks of either acupuncture or medical training therapy as monotherapies or in combination (12 interventions each), or usual care. We assessed depressiveness (PHQ-9), anxiety (GAD-7), and health-related quality of life (SF-12) as secondary outcome parameters at baseline, six weeks, three months, and six months after initiation of treatment. Linear mixed models were calculated. Results Both, acupuncture (baseline to six-weeks change scores: mean: −2(standard deviation: 2.5 points), three months: −2.4(2.4), six-months −2.7(3.6)) and the combination of acupuncture and medical training therapy (−2.7(4.9), −2.2(4.0), −2.2(4.2)) (each within-group p < .05) significantly reduced depressiveness-scores (PHQ-9) to a greater extent than medical training therapy (−0.3(2.0), −0.5(1.6), −0.9(2.6)) or usual care alone (−0.8(2.9), 0.1(2.8), 0.2(3.6)). We found similar results with anxiety scores and the physical sum scores of the SF-12. No severe adverse events occurred. Conclusions Acupuncture and the combination of acupuncture and medical training therapy elicit positive effects on depression, anxiety, quality of life, and symptom intensity in patients with episodic and chronic tension-type headache. Acupuncture appears to play a central role in mediating the therapeutic effects, underscoring the clinical relevance of this treatment. An additive benefit of the combination of both therapies does not appear to be relevant. Trial registration: Registered on 11 February 2019. German Clinical Trials Register, DRKS00016723.
Arthroscopic Remplissage Combined With Bankart Repair Results in a Higher Rate of Return to Sport in Athletes Compared With Bankart Repair Alone or the Latarjet Procedure: A Systematic Review and Meta-analysis
Authors: Davis William H. , DiPasquale Jake A. , Patel Reema K. , Sandler Alexis B. , Scanaliato John P. , Dunn John C. , Parnes Nata 
Published: January 2023

Background: Traumatic anterior shoulder instability affects athletes at a higher rate compared with the general population. In recent years, indications for arthroscopic remplissage, an adjunct procedure classically used to reduce the recurrence of anterior shoulder instability in patients with off-track Hill-Sachs lesions, have expanded. Purpose: To investigate return-to-sport (RTS) rates, functional outcomes, and adverse events in athletes who underwent arthroscopic Bankart repair with remplissage compared with surgical alternatives such as Bankart repair alone or the Latarjet procedure. Study Design: Systematic review and meta-analysis; Level of evidence, 4. Methods: A literature review of the Embase, PubMed (MEDLINE), and Web of Science databases was conducted for articles published before May 22, 2022. For the systematic review, 16 of 457 studies that reported RTS rates at any time point after remplissage were deemed eligible for inclusion in quantitative analysis and 17 of 457 studies in qualitative analysis. For the meta-analysis, 8 of 457 studies reported RTS rates after remplissage compared with surgical alternatives including Bankart repair alone or the Latarjet procedure and were deemed eligible for inclusion. Results: In total, 538 athletes underwent remplissage and were included in the study. RTS at any level was achieved by 86% (395/457) of patients, and the odds of RTS at any level were significantly higher after remplissage compared with surgical alternatives (odds ratio [OR], 2.71 [95% CI, 1.14-6.43]; P = .02). The odds of RTS at a previous or higher level were also significantly higher after remplissage compared with surgical alternatives (OR, 2.07 [95% CI, 1.29-3.31]; P = .002). The mean Rowe score increased significantly from 43.9 ± 7.77 preoperatively (n = 173) to 92.2 ± 4.02 after remplissage (n = 397) ( P < .001), but there was no significant difference in Rowe scores between remplissage and surgical alternatives ( P = .54). After remplissage, the recurrence rate was 5.0% for athletes (n = 220) and 7.3% for all patients (n = 634), with a mean time to recurrence of 24.0 ± 12.5 months. Reoperations occurred in 3.6% of athletes (n = 110) and 4.1% of all patients (n = 445). Recurrence and reoperations were significantly less likely after remplissage compared with surgical alternatives (OR, 0.18 [95% CI, 0.08-0.39]; P < .001 and OR, 0.17 [95% CI, 0.06-0.50]; P = .001, respectively). Conclusion: Arthroscopic Bankart repair with remplissage augmentation significantly improved RTS rates among athletes, both at any level and at previous levels of play. Additionally, remplissage appeared to significantly decrease recurrence and reoperation rates compared with surgical alternatives such as Bankart repair alone or the Latarjet procedure.
Test accuracy of artificial intelligence-based grading of fundus images in diabetic retinopathy screening: A systematic review
Authors: Zhelev Zhivko , Peters Jaime , Rogers Morwenna , Allen Michael , Kijauskaite Goda , Seedat Farah , Wilkinson Elizabeth , Hyde Christopher 
Published: January 2023

Objectives To systematically review the accuracy of artificial intelligence (AI)-based systems for grading of fundus images in diabetic retinopathy (DR) screening. Methods We searched MEDLINE, EMBASE, the Cochrane Library and the ClinicalTrials.gov from 1st January 2000 to 27th August 2021. Accuracy studies published in English were included if they met the pre-specified inclusion criteria. Selection of studies for inclusion, data extraction and quality assessment were conducted by one author with a second reviewer independently screening and checking 20% of titles. Results were analysed narratively. Results Forty-three studies evaluating 15 deep learning (DL) and 4 machine learning (ML) systems were included. Nine systems were evaluated in a single study each. Most studies were judged to be at high or unclear risk of bias in at least one QUADAS-2 domain. Sensitivity for referable DR and higher grades was ≥85% while specificity varied and was <80% for all ML systems and in 6/31 studies evaluating DL systems. Studies reported high accuracy for detection of ungradable images, but the latter were analysed and reported inconsistently. Seven studies reported that AI was more sensitive but less specific than human graders. Conclusions AI-based systems are more sensitive than human graders and could be safe to use in clinical practice but have variable specificity. However, for many systems evidence is limited, at high risk of bias and may not generalise across settings. Therefore, pre-implementation assessment in the target clinical pathway is essential to obtain reliable and applicable accuracy estimates.
Effect of Prefeeding Oromotor Stimulation on Oral Feeding Performance of Preterm Neonates during Hospitalization and at Corrected One Month of Age at a Tertiary Neonatal Care Unit of India: A Randomized Controlled Trial
Authors: Sasmal Suvashri , Shetty Asha P. , Saha Bijan , Knoll Brenda , Mukherjee Suchandra 
Published: January 2023

Aim To evaluate the effect of prefeeding oromotor stimulation on preterm infants’ feeding performance during hospitalization and in early infancy. Methods Twenty nine preterm neonates born between 26 and 32 weeks of gestation were randomized to receive either 5 minutes of prefeeding oromotor stimulation or routine care. Results Improvement in mean (SD) scores of feeding performance measured by various standardized scales were higher in the study group ( p <.001). There were a higher number of preterms of the intervention group on mothers’ milk at discharge and at corrected one month of age. They achieved independent oral feeding at significantly lower body weight ( p <.001) and had a shorter duration of hospitalization ( p <.05). No significant difference was found in the weight gain rate of preterm infants during hospitalization and at corrected one month of age. Conclusion Prefeeding oromotor stimulation improves feeding performance and shortens hospital stay in preterm neonates and improves the breastfeeding rate at their corrected one month of age.
Optical coherence tomography and angiography in Alzheimer's disease and other cognitive disorders
Authors: Moussa Mohamed , Falfoul Yousra , Nasri Amina , El Matri Khaled , Kacem Imen , Mrabet Saloua , Chebil Ahmed , Gharbi Alya , Gouider Riadh , El Matri Leila 
Published: January 2023

Aims The aims of this study were to analyze retinal and choroidal changes on optical coherence tomography (OCT) and OCT-Angiography (OCT-A) in Alzheimer's disease (AD) patients and compare them to other forms of major dementia. We also aimed to analyze the correlation between clinical severity of global cognitive deficiency assessed by the mini-mental state exam (MMSE) score and OCT/OCT-A parameters. Methods Retrospective cross-sectional evaluative study of AD, and age-and gender-matched patients with other dementias. Fundus examination, OCT and OCT-A were compared. Results Ninety-one eyes of AD patients and 53 eyes of patients with other dementias were included. Retinal deposits were found in 6.59% of AD cases. OCT highlighted the presence of hyperreflective deposits and localized areas of outer retina and ellipsoid zone disruption, respectively in 20.87% and 15.38% of AD cases. Hyperreflective foci were noted within inner retinal layers in 4.39% of AD cases. Quantitative analysis revealed a thicker nasal retinal nerve fiber layer (p = 0.001) and ganglion cell complex in superior (p = 0.011) and temporal quadrants (p = 0.009) in eyes of AD patients, compared to other dementias. OCT-A showed a significantly higher fractal dimension of both superficial and deep capillary plexus (p = 0.005), with lower choriocapillaris density (p = 0.003) in AD patients. Conclusions Structural OCT could highlight the presence of hyperreflective deposits in AD, probably reflecting beta-amyloid deposits, associated to outer retinal disruptions. Quantitative OCT analysis showed structural differences between AD patients and other dementias, and combined OCT-A could identify microvascular changes in AD patients representing new potential differential diagnosis criteria.
Thermal comfort analysis of auto-racing suits using a dynamic thermal manikin
Authors: Riedy Reannan , McQuerry Meredith 
Published: January 2023

Motorsports athletes compete at high speeds for, on average, three to four hours in a cockpit that can reach temperatures of 50°C. While engineers have worked to create a faster car and safer conditions, the comfort of the driver is often sacrificed. Motorsports governing bodies require that a driver’s racing suit meet at least one of several certification levels for thermal protection. While much research and testing go into certification, there continues to be a lack of information in the body of research regarding the impact of the racing suit on thermal comfort and heat stress. Therefore, the purpose of this research was to determine the impact of auto-racing personal protective clothing on the thermal comfort of race car drivers by utilizing a thermal manikin to observe the thermal insulation, evaporative resistance, and total heat loss (THL) of standard racing suits. Racing suit systems of varying SFI Foundation, Inc. (SFI) certification levels were purchased and analyzed using an ANDI sweating thermal manikin in an environmental chamber. Results from this research demonstrate that the average predicted THL for an SFI compliant racing ensemble is 172 W/m2. Findings indicate it is more beneficial for thermal comfort to wear a lower rated suit with base layers as opposed to a higher rated suit without undergarments. More research must be done to better understand how the predicted THL for racing ensembles effects the human body when performing under race day conditions, and to determine a minimum THL benchmark for racing ensembles.
Percutaneous Suture - Closure Device Used for Iatrogenic Carotid Artery Injury Management: Case Report and Review of Literature
Authors: Hu Yizhou , Al Khiami Belal 
Published: January 2023

Accidental carotid artery injury is an uncommon but serious central venous catheter insertion complication. Hemostasis might not be readily achieved by manual compression; therefore, surgery or endovascular treatment remains the mainstay for accidental carotid artery injury. However, not all patients are suitable candidates for surgery. Vascular closure devices are widely used in femoral arteries to achieve hemostasis and early ambulation. The use of vascular closure devices is occasionally reported in other vascular beds. Here we present a case of an iatrogenic left common carotid artery injury treated by vascular closure device, which is of help in the future management of this complication.
A single-center comparative study with large sample size on stent-assisted coiling versus coiling alone for the ruptured anterior communicating artery aneurysms: Analysis of safety, efficacy, and prognosis based on propensity score matching
Authors: Shang Wei , Chang Xiaoting , Xu Yousong , Dong Bin 
Published: January 2023

Objective To compare the safety, efficacy, and prognosis of stent-assisted coiling (SAC) versus coiling alone (CA) in the treatment of ruptured anterior communicating artery aneurysms (ACoAAs). Methods The clinical and follow-up data of ruptured ACoAAs treated with endovascular treatment in our center from January 2011 to January 2021 were retrospectively collected. Patients were divided into an SAC group and a CA group based on whether stents were used, after which the two groups were matched for propensity scores. The general clinical data, embolization effect, perioperative complications, clinical, and follow-up results after matching were compared. Results A total of 354 patients were enrolled, of whom 147 patients (41.5%) received SAC and the rest received CA. Comparison baseline of two groups showed that patients with a larger diameter, wide neck, irregular morphology, and anterior direction were more likely to receive SAC. After propensity score matching, 113 patients were included in each group. Immediately postoperative angiography results showed that the complete embolization rate of patients in the SAC group was significantly lower than that in the CA group (62.8% vs. 76.1%, p = 0.03). There were no significant differences between the two groups in the incidence of perioperative complications, mortality, poor prognosis at discharge or follow-up, mid-term complete occlusion rate and recurrence rate. Conclusion The stent-assisted treatment of ruptured ACoAAs did not increase the risk of perioperative complications or the probability of poor prognosis, indicating that SAC treatment of ruptured ACoAAs is safe and feasible and has a reliable mid-term cure rate.
Management paradigms of persistent primitive trigeminal artery aneurysms: A systematic review and analysis of techniques and complications from 1960s to 2022: From conservative to surgical to endovascular, how far along the right path are we?
Authors: Sreenivasan Sanjeev , Agarwal Neha , Roychowdhury Sudipta , Khandelwal Priyank , Sun Hai , Singla Amit , Sonig Ashish , Gupta Gaurav 
Published: January 2023

Introduction Aneurysms of persistent primitive trigeminal artery (PPTAAs) are increasingly reported and commonly managed by endovascular (EN) techniques. There are no systematic reviews or meta-analyses which analyse outcomes and complications of treatment modalities for PPTAAs. We aim to highlight the change in trend of management of PPTAAs and to identify clinical and radiological parameters which may influence management paradigms. Methodology A systematic search of literature was done in PubMed, Embase, Google Scholar, Cochrane library and Medline using keywords ‘persistent primitive trigeminal artery’, ’aneurysms’, ‘embolization’, ‘surgical clipping’, etc. Only cases reporting aneurysms of PPTA were included. Three subgroups, such as conservative, open surgical (OS) and EN interventional, were studied for outcome evaluation. In the EN subgroup, relation of clinical and radiological parameters with outcome (complete/partial occlusion) was analysed using Microsoft Excel Data Analysis ToolPak. Results Of the 101 articles found eligible for assessment, 54 were analysed quantitatively. Mortality in the conservative group was 12.5% and OS group was 9.09%. After EN treatment, complete angiographic occlusion was seen in 88.89% PPTAAs and 5.5% warranted retreatment. In the EN subgroup, location ( p=0.17), shape ( p=0.69), Saltzman circulation ( p=0.26) or status of rupture ( p=0.08) did not significantly impact angiographic occlusion outcome. Multivariate regression analysis showed 6.6% influence of independent variables, that is, age, gender, aneurysm location, side, shape (saccular/fusiform), rupture status and type of Saltzman circulation on aneurysm occlusion outcome [F(7,27) =1.34] ( p=0.27). Total mortality reported in the EN group was 8.57%. Conclusion Clinical or radiological parameters do not influence angiographic occlusion outcome. Although EN techniques are successful, meticulous reporting of outcomes and complications is important.
MyDietCam: Development and usability study of a food recognition integrated dietary monitoring smartphone application
Authors: Kong Nadine Alvina , Moy Foong Ming , Ong Shu Hwa , Tahir Ghalib Ahmed , Loo Choo Kiong 
Published: January 2023

Background Diet monitoring has been linked with improved eating habits and positive health outcomes such as prevention of obesity. However, this is often unsustainable as traditional methods place a high burden on both participants and researchers through pen and paper recordings and manual nutrient coding respectively. The digitisation of dietary monitoring has greatly reduced these barriers. This paper proposes a diet application with a novel food recognition feature with a usability study conducted in the real world. Methods This study describes the development of a mobile diet application (MyDietCam) targeted at healthy Malaysian adults. Focus group discussions (FGD) were carried out among dietitians and potential users to determine ideal features in a diet application. Thirty participants were recruited from a local university to log their meals through MyDietCam for six days and submit the Malay mHealth Application Usability Questionnaire (M-MAUQ) at the end of the study. Results The findings from the FGD led to the implementation of the main features: individualised recommendations, food logging through food recognition to reduce steps for data entry and provide detailed nutrient analyses through visuals. An average overall usability score of 5.13 out of a maximum of seven was reported from the M-MAUQ which is considered acceptable. Conclusion The development of a local (Malaysian) mobile diet application with acceptable usability may be helpful in sustaining the diet monitoring habit to improve health outcomes. Future work should focus on improving the issues raised before testing the effectiveness of the application for improving health outcomes.
Comparative Effectiveness, Efficiency, and ED Nurse Preference Between Two Methods of Visualization for Midline Catheter Insertion: A Pilot Study
Authors: Alsbrooks Kimberly , Hoerauf Klaus 
Published: January 2023

Introduction Rapid and reliable peripheral IV access is essential for many patients admitted to the emergency department (ED) to ensure administration of life-saving medications, and successful intravenous cannulation can significantly affect patient care. Objective The objective of this study was to assess the impact of a continuous needle tracking system on the accuracy, speed, and quality of ultrasound-guided peripheral venous catheter insertions. Methods A convenient sample study based on the study setting using simulated tissue was conducted with 49 US-based ED nurses to compare the insertion of a midline catheter using traditional ultrasound guidance versus an advanced needle-tracking technology along with ultrasound guidance. The purpose of this evaluation was to assess the impact of continuous needle tracking system. Informed consent was obtained from all individual participants involved in this study. All participants were made aware that the results may be published. There was no IRB approval for this study. All sources were properly disclosed within the text. Results The addition of the advanced needle-tracking technology significantly reduced total insertion attempts, insertion time, backwall penetrations, and redirects (probes to hit the target vein), while improving image clarity and confidence for participants. Conclusion The innovative needle-tracking system evaluated in this pilot study has the potential to improve emergent difficult vascular access. EDs should assess the value of this technology to potentially improve the management of difficult intravenous access patients in their settings.
Comorbidities in transplant recipients with acute myeloid leukemia receiving low-intensity conditioning regimens: an ALWP EBMT study
Authors: Fein Joshua A. , Shouval Roni , Galimard Jacques-Emmanuel , Labopin Myriam , Socié Gérard , Finke Jürgen , Cornelissen Jan J. , Malladi Ram , Itälä-Remes Maija , Chevallier Patrice , Orchard Kim H. , Bunjes Donald , Aljurf Mahmoud , Rubio Marie Thérèse , Versluis Jurjen , Mohty Mohamad , Nagler Arnon 
Published: January 2023

Abstract
Older age and a high burden of comorbidities often drive the selection of low-intensity conditioning regimens in allogeneic hematopoietic stem cell transplantation recipients. However, the impact of comorbidities in the low-intensity conditioning setting is unclear. We sought to determine the contribution of individual comorbidities and their cumulative burden on the risk of nonrelapse mortality (NRM) among patients receiving low-intensity regimens. In a retrospective analysis of adults (≥18 years) who underwent transplantation for acute myeloid leukemia in the first complete remission between 2008 and 2018, we studied recipients of low-intensity regimens as defined by the transplantation conditioning intensity (TCI) scale. Multivariable Cox models were constructed to study associations of comorbidities with NRM. Comorbidities identified as putative risk factors in the low-TCI setting were included in combined multivariable regression models assessed for overall survival, NRM, and relapse. A total of 1663 patients with a median age of 61 years received low-TCI regimens. Cardiac comorbidity (including arrhythmia/valvular disease) and psychiatric disease were associated with increased NRM risk (hazard ratio [HR], 1.54; 95% confidence interval [CI], 1.13-2.09 and HR, 1.69; 95% CI, 1.02-2.82, respectively). Moderate pulmonary dysfunction, though prevalent, was not associated with increased NRM. In a combined model, cardiac, psychiatric, renal, and inflammatory bowel diseases were independently associated with adverse transplantation outcomes. These findings may inform patient and regimen selection and reinforce the need for further investigation of cardioprotective transplantation approaches.