bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk Assessment in the Auditing Organization in Accordance with International Quality Management Standard (ISQM) 1
Authors: Kochinev Yuriy 
Published: September 2023

The article is devoted to a topical issue — the development of a methodology for assessing risks associated with the quality of work of an audit organization. The need to identify and assess the risks associated with quality, as well as the development of response measures by the audit organization, are established by the International Standard for Quality Management (ISQM) 1, the provisions of which are applicable from 12/15/2022. Th e purpose of the work is to develop a methodology for assessing risks associated with the quality of the work of an audit organization. The article substantiates the choice of a method for assessing risks associated with quality; identified and systematized the reasons for the occurrence of risks associated with quality; on the basis of the «fuzzy sets» method, the risk assessment associated with quality is formalized.
Participation in inpatient care from the perspective of family members of palliative care patients
Authors: Saarinen Johanna , Mishina Kaisa , Soikkeli-Jalonen Anu , Konradsen Hanne , Haavisto Elina 
Published: September 2023

Background: The participation of family members in inpatient palliative care has been shown to be meaningful; it contributes to the wellbeing of the patient. Even so, little is known about the perspectives of family members regarding their participation in this type of care. Aim: The aim of this study was to describe participation in inpatient care from the perspective of family members of palliative care patients. Method: This study involved semi-structured individual interviews with family members (n=19) of patients receiving inpatient palliative care, as well as inductive thematic analysis. Findings: Four main themes describing the family members’ perspectives of their participation in inpatient palliative care were identified: family members attending to everyday activities, importance of participation to family members, family members providing emotional support to patients and the role of family members in discussions and decision-making processes concerning patient care. Conclusion: Family members participate in inpatient palliative care in different ways. Participation was experienced as important to patients and family members, and some family members felt that participation may have supported their coping process.
Prevalence and incidence of tuberculosis infection among healthcare workers in chest diseases hospitals, Bangladesh: Putting infection control into context
Authors: Islam Md. Saiful , Gurley Emily S. , Banu Sayera , Hossain Kamal , Heffelfinger James D. , Amin Chowdhury Kamal Ibne , Ahmed Shahriar , Afreen Sadia , Islam Mohammad Tauhidul , Rahman Syed Mohammad Mazidur , Rahman Arfatur , Pearson Michele L. , Chai Shua J. 
Published: September 2023

Background
Healthcare workers (HCWs) are at increased risk of tuberculosis infection (TBI). We estimated the prevalence and incidence of TBI and risk factors among HCWs in Bangladeshi hospitals to target TB infection prevention and control (IPC) interventions.

Methods
During 2013–2016, we conducted a longitudinal study among HCWs in four chest disease hospitals. At baseline, we administered a questionnaire on sociodemographic and occupational factors for TB, tuberculin skin tests (TST) in all hospitals, and QuantiFERON ®-TB Gold in-Tube (QFT-GIT) tests in one hospital. We assessed factors associated with baseline TST positivity (induration ≥10mm), TST conversion (induration increase ≥10mm from baseline), baseline QFT-GIT positivity (interferon-gamma ≥0.35 IU/mL), and QFT-GIT conversion (interferon-gamma <0.35 IU/mL to ≥0.35 IU/mL). We included factors with a biologically plausible relationship with TBI identified in prior studies or having an association (p = <0.20) in the bivariate analyses with TST positivity or QFT-GIT positivity in multivariable generalized linear models. The Kaplan-Meier was used to estimate the cumulative TBI incidence rate per 100 person-years.

Results
Of the 758 HCWs invited, 732 (97%) consented to participate and 731 completed the one-step TST, 40% had a positive TST result, and 48% had a positive QFT-GIT result. In multivariable models, HCWs years of service 11–20 years had 2.1 (95% CI: 1.5–3.0) times higher odds of being TST-positive and 1.6 (95% CI 1.1–2.5) times higher odds of QFT-GIT-positivity at baseline compared with those working ≤10 years. HCWs working 11–20 years in pulmonary TB ward had 2.0 (95% CI: 1.4–2.9) times higher odds of TST positivity, and those >20 years had 2.5 (95% CI: 1.3–4.9) times higher odds of QFT-GIT-positivity at baseline compared with those working <10 years. TBI incidence was 4.8/100 person-years by TST and 4.2/100 person-years by QFT-GIT. Females had 8.5 (95% CI: 1.5–49.5) times higher odds of TST conversion than males.

Conclusions
Prevalent TST and QFT-GIT positivity was associated with an increased number of years working as a healthcare worker and in pulmonary TB wards. The incidence of TBI among HCWs suggests ongoing TB exposure in these facilities and an urgent need for improved TB IPC in chest disease hospitals in Bangladesh.
The Problem of Rabies Vaccination in Children; an Analysis of Children Bitten by Rabid and Rabid-Suspected-Animals
Authors: Munir Muzief 
Published: September 2023

The analysis of 234 Children, under 14 years of age, with the diagnosis of an animal bite was carried out in an attempt to find out problems of rabies vaccination in the children.
One of the most important factors in eliminating or at least greatly reducing rabies, is the public dissemination of information concerning not only the danger of unbzjected animals, but how rabies can be prevented or terminated if treated immediately.
Two ml of NTV was given for 14 consecutive days regardless of Â·the age of the victims, the site and the severity of the wounds, and the time span between the bite and the start of vaccinaton. ARS was never used regardless of the site and the severity of the wounds.
It is clearly seen from this analysis that the regime used in this report is safe and effective enough to prevent the victims from contracting rabies as long as the vaccination can be started within 10 days after being bitten. ARS must be given to the victims with head or back bites when the lapse of time between the bite and the start of vaccination is more than 10 days and can justifiably be instituted in arm and leg bite victims when the time span between the bite and the start of vaccinaion is more than 21 days.
Oral Rehydration Solution: An Appropriate Formula for Acute Infantile Diarrhoea
Authors: Sunoto Sunoto , Suharyono Suharyono , Wibowo Suryono , Wibowo Wibowo 
Published: September 2023

A new formula of oral rehydration solution (kristalyte R) with the following composition: Na 51.2, K 25.0, C/ 37.5, Citrate 57.5 mEq/L, dextrose 100 and sucrose 52.0 mMol/L with the osmolality of 323 mOsm/L were tried in 21 acute infantile gastroenteritis with mild and moderate dehydration. The age of the patients varied from 2.5 to 36 months with the average of 13.4 months.
As a control were used 21 children with the same age, same diagnosis and same nutritional state treated with oralyte with the composition of Na 90, K 15, Cl 75, HC03 30 mEq/L and glucose 120 mMol/L with the osmolality of 330 mOsm/L.
Clinical observation and chemical observation were done before and after rehydration which usually occurred after 24 hours of treatment.
Stool culture, W BC count and urinalysis were done on admission only.
The results of the trial revealed that in kristalyte group better results were obtained in gaining the body weight, reducing the frequency of diarrhoea or fluid loss, acceptance of the solution and reducing the risk of periorbital oedema.
No hypernatremia and neurological manifestations were found in both groups and all of the children were discharged on the third day in good condition.
Catharanthus roseus (L.) G. Don counteracts the ampicillin resistance in multiple antibiotic-resistant Staphylococcus aureus by downregulation of PBP2a synthesis
Authors: Shil Aparna , Mukherjee Sushmit , Biswas Prerona , Majhi Sudipta , Sikdar Sima , Bishayi Biswadev , Sikdar née Bhakta Mausumi 
Published: September 2023

Abstract
It is essential to revisit the global biodiversity, search for ethnopharmacologically relevant plants, and unveil their untapped potential to overcome the complications associated while treating infections triggered by multiple antibiotic-resistant Staphylococcus aureus. Catharanthus roseus (L.) G. Don of the Apocynaceae family is a medicinal plant used for remedial purposes against infectious diseases from ancient times. In this study, we intended to evaluate the mechanism by which the ethanolic extract of C. roseus root (EECRR) causes the reversal of ampicillin resistance in S. aureus. To achieve this goal, we have stained EECRR-treated S. aureus with acridine orange, analysed DNA damage by comet assay, and studied the alteration of plasmid band pattern and expression of penicillin-binding protein 2a (PBP2a) protein. Experiments revealed better S. aureus killing efficiency of EECRR at its minimum inhibitory concentration (MIC) doses due to DNA damage and reducing plasmid band intensities along with a decline in the expression of PBP2a in EECRR-treated cells at half-MIC dose. EECRR proved to be an efficient growth inhibitor of S. aureus that reduces the expression of PBP2a. Therefore, EECRR can also render ampicillin-resistant S. aureus susceptible to the antibiotic.
Extraction, phytochemical characterization, and antifungal activity of Salvia rosmarinus extract
Authors: Aamer Helmy A. , Al-Askar Abdulaziz A. , Gaber Mahmoud A. , El-Tanbouly Rania , Abdelkhalek Ahmed , Behiry Said , Elsharkawy Mohsen M. , Kowalczewski Przemysław Łukasz , El-Messeiry Sarah 
Published: September 2023

Abstract
In the current study, we used high-performance liquid chromatography (HPLC) and gas chromatography–mass spectrometry (GC–MS) to investigate and analyze the methanolic extract of Salvia rosmarinus leaves. HPLC analysis showed that the extract revealed a diverse array of polyphenolic compounds, including apigenin, catechin, chlorogenic acid, cinnamic acid, caffeic acid, coumaric acid, daidzein, ellagic acid, ferulic acid, gallic acid, hesperetin, kaempferol, methyl gallate, naringenin, pyrocatechol, quercetin, rutin, syringic acid, and vanillin. Furthermore, three fungal isolates from symptomatic strawberry plants were obtained and identified as Botrytis cinerea (OR116486), Fusarium oxysporum (OR116505), and Rhizoctonia solani (OR116525). The extract’s antifungal activity was evaluated at concentrations of 0, 50, 150, 200, and 300 µg/mL. At 200 µg/mL, the extract showed growth inhibition percentages of 74.56, 58.19, and 56.67% for R. solani, F. oxysporum, and B. cinerea, respectively, while at 300 µg/mL, all the tested fungi were completely suppressed. The GC–MS analysis revealed that the major compounds of the methanolic extract identified based on their retention times and relative peak areas (%) included β-caryophyllene (12.06%), germacrene d (13.55%), caryophyllene oxide (3.13%), methyl palmitate (5.26%), hexadecanoic acid (4.9%), and methyl stearate (6.02%). These results show rosemary extract’s potential as a source of natural antifungal agents against plant photogenic fungi. As a result, it provides a safer alternative to the current protective approaches for plant disease management.
Intelligent techno-economical optimization with demand side management in microgrid using improved sandpiper optimization algorithm
Authors: Praveen Mande , Gadi Venkata Siva Krishna Rao 
Published: September 2023

Abstract
The energy management system is established in the microgrid system for optimally integrating the Distributed Energy Resources (DERs) and generating the power distribution grids. At last, diverse mechanisms have been highly concentrated on cost reduction and at the same time, both the technical indices and economic factors are considered. Thus, this research work suggests a new heuristic algorithm termed Modified Sandpiper optimization algorithm (M-SOA) for optimal integration of DER-like Photo Voltaic (PV), wind turbines, and Energy Storage Systems (ESS) into microgrids. Here, the techno-economical optimization with ISOA is designed for determining the optimal capacity of PV, Wind Turbine, and ESS via the multi-objective function concerning measures like network power losses, voltage fluctuations, Electricity Supply Costs, initial cost, operation cost, fuel cost, and demand side management. Finally, the optimal energy management is done on distributed energy resources, and this developed model experiments on the IEEE-33 bus network. Throughout the result analysis, the developed M-SOA obtains 3.84 %, 0.98 %, 5.72 %, and 4.63 % better performance with less latency than the AGTO, BOA, WOA, and SOA. Finally, the result evaluation is done for minimizing the Electricity Supply Costs, initial cost, operation cost, and fuel cost and maximize energy efficiency.
Engineering fault intelligent monitoring system based on Internet of Things and GIS
Authors: Su Xiaoxing 
Published: September 2023

Abstract
The power grid (referred to as PG for convenience) structure is becoming increasingly complex. Aiming at the problem that it is difficult for traditional PG monitoring methods to accurately detect PG faults, an intelligent PG fault monitoring system is constructed using Internet of Things (IoT) and geographic information system (GIS) to improve the effectiveness of fault monitoring. The sensor equipment is used to collect the current information in the circuit, and the change of induced current is used to judge the cause of the fault, and the fault information is transmitted to the monitoring center through communication technology. The staff can directly locate the geographical location of the fault in the visual interface. One hundred overhead lines of Xianyang Power Supply Company are selected for analysis, and the performance of the traditional PG monitoring method and intelligent PG fault monitoring system is compared. The average fault detection accuracy of the traditional PG monitoring method and the system proposed in this article is 72.0 and 94.8%, respectively. The average fault location accuracy of the traditional PG monitoring method and this system is 80.8 and 96.5%, respectively. The intelligent monitoring system of PG fault based on IoT and GIS has high accuracy in PG fault detection and fault location, which can improve the effectiveness of fault monitoring.
P2Y6Receptor-Dependent Microglial Phagocytosis of Synapses during Development Regulates Synapse Density and Memory
Authors: Dundee Jacob M. , Puigdellívol Mar , Butler Richard , Brown Guy C. 
Published: September 2023

During brain development, excess synapses are pruned (i.e., removed), in part by microglial phagocytosis, and dysregulated synaptic pruning can lead to behavioral deficits. The P2Y6receptor (P2Y6R) is known to regulate microglial phagocytosis of neurons, and to regulate microglial phagocytosis of synapses in cell culture andin vivoduring aging. However, currently it is unknown whether P2Y6R regulates synaptic pruning during development. Here, we show that P2Y6R KO mice of both sexes had strongly reduced microglial internalization of synaptic material, measured as Vglut1 within CD68-staining lysosomes of microglia at postnatal day 30 (P30), suggesting reduced microglial phagocytosis of synapses. Consistent with this, we found an increased density of synapses in the somatosensory cortex and the CA3 region and dentate gyrus of the hippocampus at P30. We also show that adult P2Y6R KO mice have impaired short- and long-term spatial memory and impaired short- and long-term recognition memory compared with WT mice, as measured by novel location recognition, novel object recognition, and Y-maze memory tests. Overall, this indicates that P2Y6R regulates microglial phagocytosis of synapses during development, and this contributes to memory capacity.SIGNIFICANCE STATEMENTThe P2Y6receptor (P2Y6R) is activated by uridine diphosphate released by neurons, inducing microglial phagocytosis of such neurons or synapses. We tested whether P2Y6R regulates developmental synaptic pruning in mice and found that P2Y6R KO mice have reduced synaptic material within microglial lysosomes, and increased synaptic density in the brains of postnatal day 30 mice, consistent with reduced synaptic pruning during development. We also found that adult P2Y6R KO mice had reduced memory, consistent with persistent deficits in brain function, resulting from impaired synaptic pruning. Overall, the results suggest that P2Y6R mediates microglial phagocytosis of synapses during development, and the absence of this results in memory deficits in the adult.
RECORDING CONDITIONS AND PROCESSING OPTIMIZATION FOR HOLOGRAMS USING BAYFOL HX200 PHOTOPOLYMER FILM
Authors: Ivliev Vyacheslav S. , Kozin Roman A. , Voropaev Ilya S. , Sharov Daniil D. , Stafeev Sergey K. 
Published: September 2023

This work aims to analyze the process of recording and reconstructing holograms based on Denisyuk’s method, as well as calculating the power of the reference ZZZyclops camera laser beam required to record a hologram on the photopolymer film Bayfol HX200. We have studied how ultraviolet light and intense light affect the quality of holograms immediately after recording. Our experimental findings demonstrate that curing a hologram with ultraviolet light improves brightness and enhances color transfer, with better results achieved through longer exposure times. Additionally, our experiment reveals that strong illumination of a newly recorded hologram can severely damage the image and distort the object’s information. We have estimated the dosage of emission absorbed by the film and compared our results with the dosages recommended by the manufacturer.
Spectrofluorimetric determination of chlorophyll a in arugula extracts
Authors: Čakić Semenčić M. , Smoljo J. , Šupljika F. 
Published: September 2023

AbstractAs a principal pigment in plants, chlorophyll a (Chl a) is widely used to evaluate quality changes and senescence process during storage of leafy vegetables. The determination of Chl a in plant extracts by spectrophotometric methods using various empirical equations is often unreliable. Considering the sensitivity of fluorescence detection, we report here a simple, inexpensive spectrofluorimetric method that can detect and quantify Chl a in plant extracts. The fluorescence standard used for the quantitative determination of Chl a was isolated in our laboratory from the extract of Anthrospira platensis (Spirulina). The method proved to be reliable, fast, and low cost in a study of the influence of the most commonly used domestic storage conditions on Chl a degradation in fresh-cut arugula.
Differences in Outcomes by Place of Origin among Hispanic Patients with Kidney Failure
Authors: Rizzolo Katherine , Cervantes Lilia , Wilhalme Holly , Vasilyev Arseniy , Shen Jenny I. 
Published: September 2023

Significance Statement
Hispanic patients are known to have a higher risk of kidney failure and lower rates of home dialysis use and kidney transplantation than non-Hispanic White patients. However, it is unknown whether these outcomes differ within the Hispanic community, which is heterogeneous in its members’ places of origins. Using United States Renal Data System data, the authors found similar adjusted rates of home dialysis use for patients originating from places outside the United States and US-born Hispanic patients, whereas the adjusted risk of mortality and likelihood of transplantation differed depending on place (country or territory) of origin. Understanding the heterogeneity in kidney disease outcomes and treatment within the Hispanic community is crucial in designing interventions and implementation strategies to ensure that Hispanic individuals with kidney failure have equitable access to care.

Background
Compared with non-Hispanic White groups, Hispanic individuals have a higher risk of kidney failure yet lower rates of living donor transplantation and home dialysis. However, how home dialysis, mortality, and transplantation vary within the Hispanic community depending on patients' place of origin is unclear.

Methods
We identified adult Hispanic patients from the United States Renal Data System who initiated dialysis in 2009–2017. Primary exposure was country or territory of origin (the United States, Mexico, US–Puerto Rico, and other countries). We used logistic regression to estimate differences in odds of initiating home dialysis and competing risk models to estimate subdistribution hazard ratios (SHR) of mortality and kidney transplantation.

Results
Of 137,039 patients, 44.4% were US-born, 30.9% were from Mexico, 12.9% were from US–Puerto Rico, and 11.8% were from other countries. Home dialysis rates were higher among US-born patients, but not significantly different after adjusting for demographic, medical, socioeconomic, and facility-level factors. Adjusted mortality risk was higher for individuals from US–Puerto Rico (SHR, 1.04; 95% confidence interval [CI], 1.01 to 1.08) and lower for Mexico (SHR, 0.80; 95% CI, 0.78 to 0.81) and other countries (SHR, 0.83; 95% CI, 0.81 to 0.86) compared with US-born patients. The adjusted rate of transplantation for Mexican or US–Puerto Rican patients was similar to that of US-born patients but higher for those from other countries (SHR, 1.22; 95% CI, 1.15 to 1.30).

Conclusions
Hispanic people from different places of origin have similar adjusted rates of home dialysis but different adjusted rates of mortality and kidney transplantation. Further research is needed to understand the mechanisms underlying these observed differences in outcomes.
THE FLUID PRESSURE IN A HYDRAULIC FRACTURE PERPENDICULAR TO THE HORIZONTAL WELL
Authors: Bashmakov R. A. , Fokeeva N. O. , Shammatova A. A. 
Published: September 2023

For many decades, the hydraulic fracturing method, due to its efficiency, has been actively used to increase the productivity of wells in the oil and gas industry. This article is devoted to modeling fluid filtration in a fracture obtained by hydraulic fracturing running perpendicular to the wellbore.
The cases of constant flow rate and constant pressure in the well are considered in the paper. A mathematical model of the «well – fracture – reservoir» system for the case of a hydraulic fracture perpendicular to the well is described. The solution is derived by the sequential change of stationary states method, graphs with the results of test calculations are plotted.