bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Intersection of Identities: Access to Primary Education in Kamrup District of Assam
Authors: Das Sikha , Mallick Sambit 
Published: September 2023

Abstract
Access to primary education is often interpreted as access to school education, resources inside and outside the school, the way different children are treated by teachers and peers, and even access to distinct types of schools. However, different resources are not accessible to all members of a particular social system based on their intersectional identities. The intersection of identities may be gender, caste, class, region, religion, race, and age group in the context of Assam located in the North Eastern Region of India. Further, ‘access’ is a ‘socio-cultural’ construct that involves selection and multiple interpretations. Access to primary education is linked to the socioeconomic, political, and cultural identity of an individual or a group of individuals. It is against this backdrop that this article attempts to understand the experiences and interpretations of access to primary education from an intersectional perspective. The study is based on the in-depth personal interviews with students, teachers, and parents (in total, 75 respondents) in Kamrup district of Assam, located in the North Eastern Region of India, to understand differing perspectives on access to primary education, which reflect their socioeconomic, cultural, and political locales.
Short-chain fatty acids inhibit the activation of T lymphocytes and myeloid cells and induce innate immune tolerance
Authors: Porbahaie M. , Hummel A. , Saouadogo H. , Coelho R.M.L. , Savelkoul H.F.J. , Teodorowicz M. , van Neerven R.J.J. 
Published: September 2023

Abstract
The intestinal microbiota contributes to gut immune homeostasis, where short-chain fatty acids (SCFAs) function as the major mediators. We aimed to elucidate the immunomodulatory effects of acetate, propionate, and butyrate. With that in mind, we sought to characterise the expression of SCFA receptors and transporters as well as SCFAs’ impact on the activation of different immune cells. Whereas all three SCFAs decreased tumour necrosis factor (TNF)-α production in activated T cells, only butyrate and propionate inhibited interferon (IFN)-γ, interleukin (IL)-17, IL-13, and IL-10 production. Butyrate and propionate inhibited the expression of the chemokine receptors CCR9 and CCR10 in activated T- and B-cells, respectively. Similarly, butyrate and propionate were effective inhibitors of IL-1β, IL-6, TNF-α, and IL-10 production in myeloid cells upon lipopolysaccharide and R848 stimulation. Acetate was less efficient at inhibiting cytokine production except for IFN-α. Moreover, SCFAs inhibited the production of IL-6 and TNF-α in monocytes, myeloid dendritic cells (mDC), and plasmacytoid dendritic cells (pDC), whereas acetate effects were relatively more prominent in pDCs. In monocytes and mDCs, acetate was a less efficient inhibitor, but it was equally effective in inhibiting pDCs activation. We also studied the ability of SCFAs to induce trained immunity or tolerance. Butyrate and propionate – but not acetate – prevented Toll-like receptor-mediated activation in SCFA-trained cells, as demonstrated by a reduced production of IL-6 and TNF-α. Our findings indicate that butyrate and propionate are equally efficient in inhibiting the adaptive and innate immune response and did not induce trained immunity. The findings may be explained by differential SCFA receptor and transporter expression profiles of the immune cells.
Printing a Transregional Ṭarīqa: Haji Imdadullah Makki (d. 1899) and Sufi Contestations from Thana Bhavan to Istanbul
Authors: Baig Sohaib 
Published: September 2023

Abstract
This article analyzes the prominence of print in the Sufi ṭarīqa of Haji Imdadullah Muhajir Makki (d. 1899), a pre-eminent Indian Chishti-Sabri shaykh who settled in the Ottoman Hijaz after escaping North India in the aftermath of the 1857 mutiny. It explores the transregional contexts of the publication of Haji Imdadullah’s works, in the long journey of his manuscripts from Mecca to their lithographic printing in North India and their distribution through Ottoman disciples as far as Istanbul. In this study two main lines of inquiry are followed. First, how did Imdadullah participate intimately from Mecca in the editing and publication of Arabic, Urdu, and Persian books in British India, including his famed commentary and critical edition of the Masnavi-yi Maʿnavi of Jalal al-Din Rumi (d. 1273)? Second, the article follows the emergence of broader scholarly exchanges as a series of Istanbul-based Mevlevi shaykhs became invested in Imdadullah’s publications and even translated some from Persian to Ottoman Turkish. Ultimately, this article sheds light on how such Indian – Ottoman encounters in the Hijaz were catalyzed by a common investment in the Persianate disciplines of Sufi theology and classical Persian poetry in the late nineteenth and early twentieth centuries, a period typically seen as marking the shrinking and disintegration of the Persianate world. In so doing, the article highlights how modern Sufi discourse in Persian continued to facilitate intellectual exchange between Indian and Ottoman Sufi shaykhs through the Hijaz and formed an integral pillar of transregional Persianate print culture.
Alphabet Poems and other Urdu Religious Booklets
Authors: Orsini Francesca 
Published: September 2023

Abstract
Religious booklets formed a substantial part of the boom in commercial publishing and print culture in nineteenth and early-twentieth north India, cheaply available and widely reprinted by multiple publishers. This essay considers two popular texts that allow us to trace some of the range and of the linguistic and emotional contours of this production. Alif Be alphabet poems gesture towards the earlier history of Muslim oral traditions in north India. Short Wafātnāma verse narratives on the death of the Prophet Muhammad, conversely, were most likely produced by authors connected to Sunni reform movements and sought to focus their devotion on the Prophet alone.
Estimating Individual Radio Occultation Uncertainties Using the Observations and Environmental Parameters
Authors: Sjoberg Jeremiah , Anthes Richard , Zhang Hailing 
Published: September 2023

Abstract
Estimation of uncertainties (random error statistics) of radio occultation (RO) observations is important for their effective assimilation in numerical weather prediction (NWP) models. Average uncertainties can be estimated for large samples of RO observations and these statistics may be used for specifying the observation errors in NWP data assimilation. However, the uncertainties of individual RO observations vary, and so using average uncertainty estimates will overestimate the uncertainties of some observations and underestimate those of others, reducing their overall effectiveness in the assimilation. Several parameters associated with RO observations or their atmospheric environments have been proposed to estimate individual RO errors. These include the standard deviation of bending angle (BA) departures from either climatology in the upper stratosphere and lower mesosphere (STDV) or the sample mean between 40 and 60 km (STD4060), the local spectral width (LSW), and the magnitude of the horizontal gradient of refractivity (|∇HN|). In this paper we show how the uncertainties of two RO datasets, COSMIC-2 and Spire BA, as well as their combination, vary with these parameters. We find that the uncertainties are highly correlated with STDV and STD4060 in the stratosphere, and with LSW and |∇HN| in the lower troposphere. These results suggest a hybrid error model for individual BA observations that uses an average statistical model of RO errors modified by STDV or STD4060 above 30 km, and LSW or |∇HN| below 8 km.

Significance Statement
These results contribute to the understanding of the sources of uncertainties in radio occultation observations. They could be used to improve the effectiveness of these observations in their assimilation into numerical weather prediction and reanalysis models by improving the estimation of their observational errors.
PD-L1 testing in metastatic triple negative breast cancer: Results of an Italian survey
Authors: Cerbelli Bruna , Cirillo Alessio , Pomati Giulia , Pernazza Angelina , Ascione Andrea , Pisegna Simona , Pisano Annalinda , Leopizzi Martina , Pignataro Maria Gemma , Costarelli Leopoldo , Mulè Antonino , Vecchione Andrea , Catalano Piera , Coppola Luigi , Perrone Giuseppe , Perracchio Letizia , Anemona Lucia , Mastracchio Antonio , Nardi Stefano , Reitano Renato , Massari Annalisa , Grillo Lucia Rosalba , Liberati Fabrizio , Della Rocca Carlo , Marchetti Paolo , Botticelli Andrea , D’Amati Giulia 
Published: September 2023

Background: Immunotherapy has revolutionized the approach to metastatic triple-negative breast cancers. Atezolizumab was approved for patients with metastatic triple-negative breast cancers whose tumors express PD-L1, determined by SP 142 assay. To assess the availability and practice of SP142 test we administered a survey to all the 15 pathology departments of the Lazio Region during a six-month period. Methods: The survey comprised 12 questions regarding the availability of SP142 in the pathology departments, the percentage of positive tests, the difficulties of pathologists in cases close to cut-off value and the tested samples. Results: The SP142 assay was available in only eight centers. In case of positive result, most centers (5/8, 62.5%) reported values of PD-L1 expression ranging from > 1 to ⩽ 5%, with values close to the cut-off point (⩾ 1% or < 1%) being the greatest challenge. Most of the centers (6/8, 75%) tested material from both their own and other hospitals. In most centers, the evaluations were performed either on primary tumors or metastasis, in particular lymph nodes (5/8, 62.5%), followed by lung (3/8, 37.5%) and liver (1/8, 12.5%) metastasis. Conclusion: Our results raise some important issues concerning the evaluation of PD-L1 in the “real-life” setting, providing strategies for its implementation.
Effects of Smoking Marijuana on the Respiratory System: A Systematic Review
Authors: Vásconez-González Jorge , Delgado-Moreira Karen , López-Molina Belén , Izquierdo-Condoy Juan S. , Gámez-Rivera Esteban , Ortiz-Prado Esteban 
Published: September 2023

Background: The prevalence of marijuana use and its derivatives has surged over the past century, largely due to increasing legalization globally. Despite arguments advocating its benefits, marijuana smoking exposes the lungs to harmful combustion byproducts, leading to various respiratory issues such as asthma, pneumonia, emphysema, and chronic obstructive pulmonary disease. Methods: We embarked on an extensive literature search, utilizing PubMed/Medline, Scopus, Web of Science, and Google Scholar databases, identifying 200 studies. After the elimination of duplicates, and meticulous review of abstracts and full texts, 55 studies were included in our analysis. Results: Current literature demonstrates that marijuana use negatively impacts lung function, triggering symptoms like chronic cough, sputum production, and wheezing, and diminishing FEV1/FVC ratio in spirometry tests. Moreover, prolonged or chronic marijuana use augments the risk of respiratory function impairment. While the carcinogenic effects of marijuana are still contested, a weak correlation between marijuana use and lung cancer has been observed in some studies. Additionally, instances of other pathologies linked to marijuana use have been reported, including the development of COPD, pulmonary bullae, spontaneous pneumothorax, pleuritic pain, chronic pulmonary aspergillosis, hemoptysis, and pulmonary Langerhans cell histiocytosis. Conclusions: The evidence underscores that marijuana use is detrimental to respiratory health. In light of the escalating trend of marijuana use, particularly among the youth, it is imperative to advocate public health messages discouraging its consumption.
Assessing and improving the quality of guideline-adherent hepatitis B virus care in people with HIV: A cross-sectional study
Authors: Oomen Patrick GA , van Kraaij Vincent JP , Gerritsma Anna M , Verduyn Lunel Frans M , Boland Greet J , Hoepelman Andy IM , van Welzen Berend J 
Published: September 2023

The increasing use of non-tenofovir containing antiretroviral regimens calls for renewed attention to the prevention and management of hepatitis B virus (HBV) in people with HIV (PWH). We retrospectively assessed adherence to HBV guidelines, including complete HBV screening in PWH. In people with HIV/HBV co-infection, this included HBV therapy, screening for hepatitis delta virus (HDV) and on-therapy virologic response monitoring. HIV/HBV co-infection in PWH was defined as the presence of hepatitis B surface antigen (HBsAg) at the last measurement before study entry or detectable HBV-DNA for ≥6 months. After assessment, missing laboratory tests were performed to optimize HBV monitoring and screening for co-infections. Of all PWH under follow-up, 1484/1633 (90.9%) were adequately screened for HBV. After performing missing screening tests, 466 of 1618 PWH with complete screening results (28.8%) were non-immune for HBV infection. Fifty-one (3.2%) with HIV/HBV co-infection were identified. HBV treatment was adequate in 51/51 (100%). Screening for hepatitis A, C and delta virus antibodies and fibrosis was performed in 51/51 (100%), 49/51 (96.1%), 17/51 (35.3%) and 38/51 (74.5%). Annual HBV-DNA or HBsAg monitoring was done in 18/51 (35.3%) and hepatocellular carcinoma (HCC) surveillance in 2/9 (22.2%) of those indicated. Additional testing in those with missing data identified 4/34 (11.8%) persons with HDV antibodies and 3/30 (10%) with HBsAg seroclearance. Our study demonstrates the feasibility and added value of evaluating HBV care components and performing missing laboratory tests, identifying a large number of HBV vaccination candidates and HDV antibody screening, HBsAg monitoring and HCC surveillance as key areas for improvement.
Perceived stress and secondary traumatization in social workers during coronavirus disease 2019: The moderating effect of psychological capital and social work supervision
Authors: Gur Ayelet , Peled-Avram Maya , Itzchak Gili , Megira Sharon , Reich Ari , Farchi Moshe 
Published: September 2023

Summary Social workers have had a pivotal role in handling the challenges faced by people dealing with the coronavirus disease 2019 (COVID-19) pandemic. Supporting clients who have undergone traumatic experiences during a global pandemic may increase the risk of experiencing secondary traumatic stress. This study examined two protective factors that may be key in the association between stress and social workers’ secondary traumatic stress: Psychological capital (internal protective factor) and satisfaction with supervision (external factor). The study sample included 104 Israeli social workers who worked in their profession during the first year of the COVID-19 pandemic. A regression-based path analysis was conducted to test the moderation model with the PROCESS software. Findings Self-efficacy significantly moderated the association between perceived stress and intrusion; increasing self-efficacy decreases perceived stress's effect on intrusion. Although no significant moderating effect was found for the existence of supervision, the interaction between perceived stress and satisfaction with supervision was significant in predicting secondary trauma. Applications Social workers’ unions must work to improve the quality of supervision and raise awareness of the importance of supervision in general and particularly during times of crisis. Manageable workloads, a reasonable balance between work and home, and verbal and financial encouragement to seek professional psychological assistance would all be to the advantage of social workers at risk for secondary trauma.
Surgeon-Modified Fenestrated Stent-grafts for Zone 2 Endovascular Repair of Blunt Traumatic Thoracic Aortic Injury: Early and Midterm Results
Authors: Mavioglu Levent , Iscan Hakki Zafer , Askin Goktan , Akkaya Bekir Bogachan , Tumer Naim Noran , Karahan Mehmet , Unal Ertekin Utku 
Published: September 2023

Aim: Blunt traumatic thoracic aortic injury (BTAI) is a highly fatal surgical emergency and is treated with endovascular procedures. We aimed to analyze and report the early and midterm outcomes of surgeon-modified fenestrated stent-grafts (SMFSG) compared with other conventional endovascular methods in patients with BTAI repaired with zone 2 endovascular surgery. Materials and Methods: Before and after the study was performed, from January 2015 to January 2020 for a period in which conventional endovascular treatments were used and from January 2020 to January 2023 for the second period in which the SMFSG technique was used. A total of 25 patients who underwent zone 2 endovascular repair for BTAI were included. The patients treated with conventional endovascular methods in the first period, chimney thoracic endovascular aortic repair (TEVAR) (n=3 patients); Left subclavian artery (LSA)-covered (intentionally total) (n=12 patients) LSA-covered (LSAC) TEVAR; carotid-subclavian bypass TEVAR (n=2 patients) was defined as group 1, and the group of patients treated with SMFSG in the second period was defined as group 2. The primary endpoints of the study were technical success, defined as complete closure of BTAI, and in-hospital mortality. Secondary outcomes were aortic pathology-related morbidity, mortality, and re-interventions during the follow-up period. Results: The mean age was 42.6±14.3 years, and 21 (84%) of the patients were male. The patients were compared with respect to the proximal landing zone, fluoroscopy time, duration of the procedure, length of intensive care unit stay, and hospital stay, no statistically significant difference was found between the 2 groups (p>0.05). The mean follow-up time of patients in group I was 46±9 months, while in group II, it was 14±6 months (p<0.001). While no TEVAR-related complications were detected in group II throughout follow-up, they occurred in 4 patients (28.6%) in group I. Conclusion: TEVAR is the most appropriate treatment for BTAI in the modern era, especially for polytrauma patients with successful outcomes. Intentional coverage of the LSA can be performed, but SMFSG is an effective, economical, rapid, and available technique for endovascular revascularization of the LSA. Clinical Impact Altough intentional left subclavian artery coverage is preferred routinely in patients with blunt traumatic aortic injury (in Zone 2) which is a highly fatal surgical emergency, surgeon-modified fenestrated stent-grafts is also effective, economical, rapid and available technique.
Magnetic resonance imaging analysis of the distribution of cartilage damage in scaphoid nonunion
Authors: Jung Hyoung Seok , Kim Sujin , Chung Bo Mi , Lee Hyun il , Lee Jae-Sung 
Published: September 2023

This study aimed to evaluate the distribution and severity of cartilage damage using magnetic resonance imaging in patients with scaphoid nonunion without advanced wrist arthritis. We retrospectively analysed MRI of patients who underwent osteosynthesis for scaphoid nonunion. Cartilage damage was assessed in eight wrist regions using a modified Whole-Organ Magnetic Resonance Imaging Score. The frequencies of regions affected by any cartilage damage (Score ≥2.5) depicted on MRI were analysed. The study included 32 patients (31 men and one woman), with a mean age of 32 years (SD 11). The distal radioscaphoid (29/32), scaphotrapeziotrapezoid (STT) (22/32), proximal radioscaphoid (14/32) and scaphocapitate (11/32) joints were most commonly affected by degenerative cartilage damage. The STT and proximal radioscaphoid joint were especially likely to be involved in early-stage scaphoid nonunion advanced collapse. We recommend that surgeons should investigate the cartilage status of these joints during decision-making for scaphoid nonunion surgery. Level of evidence: III
Correlation between histopathological nerve assessment and clinical recovery in brachial plexus birth injuries
Authors: Moulinier Caroline , Bellity Lorie , Saghbiny Elie , Bachy-Razzouk Manon , Hanneur Malo Le , Fitoussi Frank 
Published: September 2023

In the management of brachial plexus birth palsies, the quality of the roots eligible for reconstruction is thought to be a key issue. The aim of the present study was to evaluate the correlations between pathological root examination and motor recovery after brachial plexus reconstructions. Quantitative histopathological analysis of intraneural fibrosis was conducted on 72 nerve transections (40 roots, 18 trunks and 14 suprascapular nerves) in 20 patients. Clinical recovery of targeted muscles after surgery was assessed by standardized functional scores. After a mean follow-up of 32 months, patients with a lower fibrosis rate for the suprascapular nerve had greater global Mallet scores (r = −0.57; p = 0.042) as well as a greater active shoulder flexion (r = −0.66; p = 0.015). Correlations were also found between C6 root and upper trunk fibrosis rate and some of the subsections of the Mallet score, active movement scale for the biceps and active elbow flexion. These results seem to confirm the relevance of intraoperative pathological evaluation of the roots and nerves after neuroma resection to optimally define the reconstruction strategy. Level of evidence: IV
HAHNet: a convolutional neural network for HER2 status classification of breast cancer
Authors: Wang Jiahao , Zhu Xiaodong , Chen Kai , Hao Lei , Liu Yuanning 
Published: September 2023

Abstract
Objective
Breast cancer is a significant health issue for women, and human epidermal growth factor receptor-2 (HER2) plays a crucial role as a vital prognostic and predictive factor. The HER2 status is essential for formulating effective treatment plans for breast cancer. However, the assessment of HER2 status using immunohistochemistry (IHC) is time-consuming and costly. Existing computational methods for evaluating HER2 status have limitations and lack sufficient accuracy. Therefore, there is an urgent need for an improved computational method to better assess HER2 status, which holds significant importance in saving lives and alleviating the burden on pathologists.

Results
This paper analyzes the characteristics of histological images of breast cancer and proposes a neural network model named HAHNet that combines multi-scale features with attention mechanisms for HER2 status classification. HAHNet directly classifies the HER2 status from hematoxylin and eosin (H&E) stained histological images, reducing additional costs. It achieves superior performance compared to other computational methods.

Conclusions
According to our experimental results, the proposed HAHNet achieved high performance in classifying the HER2 status of breast cancer using only H&E stained samples. It can be applied in case classification, benefiting the work of pathologists and potentially helping more breast cancer patients.