bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk Factors for Lower Respiratory Tract Infection Associated With Tracheobronchial Foreign Body Aspiration in Children
Authors: Lin Fu-Zhi , Cao Wei , Xu Bin , Liu Jia , Bi Jing , Fu Yong 
Published: December 2022

Objectives: Tracheobronchial foreign body aspiration (TFBA) is a major cause of accidental death in children. Lower respiratory tract infection (LRTI) may be caused by TFBA, but there are few reports about LRTI associated with TFBA. This study collected TFBA cases in our hospital to analyze LRTI and determine its risk factors. Methods: A total of 194 children who underwent tracheobronchial foreign body (TFB) extraction in The Children’s Hospital of Zhejiang University School of Medicine from June 2019 to April 2020 were enrolled. CT chest is routinely used in the workup of suspected airway FB at our institution to evaluate for patients, a FB was already highly suspected. The retention time was defined as from the time of TFB inhalation or presentation (if there was no history of TFBA) to the time of TFB removal. General characteristics including weight, clinical symptoms, operative records, cervicothoracic CT, retention time, type of TFB and postoperative hospitalization time were collected. Chi-square tests, rank sum tests and multivariate logistic regression analyses were performed. Results: The incidence of LRTI was 46.6%, 68.6%, and 68.6% when the retention time was within 24 hours, between 24 hours and up to 1 week and more than 1 week, respectively. Postoperative hospitalization time of LRTI group was significantly longer than that of non-LRTI group. Findings for cervicothoracic CT as pneumonia, emphysema, atelectasis meant more serious clinical manifestations and the retention time was longer in the LRTI group than in the non-LRTI group. There was a positive correlation between the retention time of a TFB and LRTI in multivariate logistic regression analysis. Conclusions: The incidence of LRTI caused by TFBA is high. LRTI is association with longer postoperative hospitalization time. The TFB retention time is an independent risk factor for LRTI. If a patient presents with significant LRTI symptoms, a course of steroids and antibiotics maybe a safer approach rather than proceeding immediately with bronchoscopic removal.
Prevalence of loneliness and its correlates among patients with schizophrenia
Authors: Suman Aarzoo , Nehra Ritu , Sahoo Swapnajeet , Grover Sandeep 
Published: December 2022

Background: There are limited data on loneliness and its correlates in patients with schizophrenia. Objective: To evaluate prevalence and correlates of loneliness in patients with schizophrenia, currently in clinical remission. Methodology: A total of 160 patients of schizophrenia in clinical remission were assessed on UCLA Loneliness Scale, Positive and Negative syndrome scale, Calgary Depression Scale for Schizophrenia (CDSS), Internalized Stigma of Mental Illness Scale, Rosenberg Self-esteem Scale, Brief COPE, Beck’s Hopelessness Scale, Brief Dyadic Scale of Expressed Emotions, and Self-report Quality of Life Measure. Results: The mean age of the study sample was 34.99 ( SD = 9.13) years. The prevalence of loneliness in the study sample was 80%, with mean total UCLA-loneliness scale score of 30.04 (16.9).Compared to participants without loneliness, those with loneliness had had higher CDSS score, had poor quality of life, lower self-esteem, experienced higher level of stigma, more often used maladaptive coping strategies such as self-blaming and reported a higher level of hopelessness. In the correlation analysis, higher level of loneliness was associated higher severity of depression, higher level of stigma (except for stigma resistance) and discrimination, poorer quality of life, lower self-esteem, perception of a higher level of expressed emotions, higher use of maladaptive coping in the domains of behavioral disengagement, and self-blaming, and a higher level of hopelessness. In regression analysis, the maximum variance of loneliness was explained by quality of life score (29%), followed by hopelessness score (8.8%) and discrimination score (2%). Conclusion: There is a high prevalence of loneliness in patients with schizophrenia, and there is a need to routinely evaluate the patients of schizophrenia for loneliness and address the same.
Study on methods to improve the mechanical properties of aramid/epoxy composites
Authors: Yermakhanova Azira Muratovna , Baiserikov Berdiyar Meirzhanuly , Kenzhegulov Aidar Karaulovich , Meiirbekov Mohammed Nurgazyuly , Zhumadilov Bauyrzhan Yerbolsynuly 
Published: December 2022

Polymer composites, in particular aramid-epoxy composites, are widely used in fields such as aerospace, transportation, electronics, etc. due to their excellent mechanical and dielectric properties. This article presents studies of modification and combined reinforcement on the mechanical properties of aramid-epoxy composites. The influence of matrix (epoxy resin) and reinforcing filler (aramid fabric) mass ratio and ways to increase strength characteristics and impact toughness of the composite were studied. Comparative results for composites made by vacuum forming and vacuum infusion methods are presented. Mass ratio of reinforcing filler and matrix varied in the range of 50:50%, 60:40%, 65:35%, and 75:25%. It was found that modifying epoxy resin with polyurethane rubber plasticizer, together with combined reinforcement of aramid fabric/aramid roving, resulted in composite strength up to 720 MPa and impact toughness of 426 kJ/m2. Modification of epoxy resin with tricresyl phosphate leads to composite strength up to 710 MPa and impact toughness of 475 kJ/m2. Thus, it is shown that modification and combined reinforcement of aramid-epoxy composites are the most effective methods to increase strength and adhesion to epoxy resin.
Perception on Anxiety among Adolescents and Mental Health Professionals and Development of Comic Strip
Authors: Ravunnikutty Pravitha Madathodiyil , Krishnamurthy Latha , Murthy Meena Kolar Sreedhara , Kapanee Aruna R. M. , Chaturvedi Santosh K. , Saini Deepika 
Published: December 2022

Background: Adolescence is a phase of many physical and psychological developments. This stage is also vulnerable to the development of mental illness. Anxiety is one of the most prevalent disorders among adolescents, which mostly onsets before puberty. This study aimed to understand the perception on anxiety among adolescents and mental health professionals and develop a comic strip on anxiety. Methods: This qualitative study involved focus group discussions (FGDs) among mental health professionals and pre-university college students. The FGD data were analyzed through direct content analysis according to the predetermined broad themes. Results: Awareness regarding anxiety was poor among adolescents, and in certain situations they were found to be reluctant to seek professional help. The comic strip on anxiety was developed based on the findings of FGD based on the themes, general awareness, factors responsible, symptoms and coping, management, and barriers to seeking professional help. Conclusions: Adolescents perceived mental health as very important for their overall health. The adolescents did not know that they were going through anxiety, but they noticed that they had some mental health issues and wanted to get out of it. The development of comic strip on anxiety for adolescents was an attempt to overcome these barriers.
Daily routine and habits during COVID-19 lockdown in Italy: An observational survey
Authors: Maritan Yuri , Pisaniello Diletta Maria , Belvedere Annalisa , Battain Pier Carlo 
Published: December 2022

Introduction: Between March–May 2020, the Italian Government applied restrictive measures to reduce the risk of contagion, fostering a potential condition of occupational deprivation. Methods: A digital survey was administered in June 2020 including closed and open questions. The goal was to report how the first Italian lockdown affected daily routine. Results: 648 surveys were valid. Most respondents were workers and spent lockdown at home. Before quarantine, the most representative occupations were working and housekeeping; the significant ones were working and meeting friends/relatives. Wellbeing meant meeting friends/relatives and hobbies/interests. During lockdown, respondents dedicated themselves to housekeeping and working; meaningful occupations were working and cooking. All data was stratified according to age and perceived wellbeing; open questions were categorized by the researchers. Discussion: A daily routine in compliance with lockdown restrictions required a change in habits. Time was used for occupations not strictly contentful; finance and work gained significance. It is to hypothesize that the idea of wellbeing was deeply altered. Conclusions: The study focuses on a slice of everyday life in times of emergency, it highlights people adaptability and their experiences according to age and future plans. Occupational justice emerges as a strong topic: the environment influences wellbeing, habits, and self-perception.
Does Multicomponent Physical Exercise Training Work for Dementia? Exploring the Effects on Cognition, Neuropsychiatric Symptoms, and Quality of Life
Authors: Borges-Machado Flávia , Teixeira Laetitia , Carvalho Joana , Ribeiro Oscar 
Published: December 2022

Objective To explore the effects of a multicomponent training (MT) physical exercise intervention in the cognitive function, neuropsychiatric symptoms, and quality of life of older adults with major neurocognitive disorder (NCD). Methods Quasi-experimental controlled trial. Thirty-six individuals (25 female) were equally distributed to an exercise group (aged 74.33 ± 5.87 years) or a control group (aged 81.83 ± 6.18 years). The Alzheimer’s Disease Assessment Scale – Cognitive (ADAS-Cog), the Neuropsychiatric Inventory (NPI) and the Quality of Life – Alzheimer’s Disease (QoL-AD) tests were performed before and after the intervention. Results There was no clear interaction effect factor of intervention on ADAS-Cog (B = 1.33, 95% CI: -2.61 – 5.28, P = .513), NPI (B = −8.35, 95% CI: −18.48 – 1.72, P = .115), and QoL-AD (B = 2.87, 95% CI: .01 – 5.73, P = .058). Conclusions The 6-month MT physical exercise intervention did not present evidence of slowing down cognitive decline neither improving neuropsychiatric symptomatology, and quality of life of older adults with major NCD. Future studies with larger samples are needed to better understand the impact of physical exercise interventions using MT methodology on specific cognitive abilities, neuropsychiatric symptoms, and quality of life domains.
Tamoxifen induced hands deformities
Authors: Bendarkawi Yasmine , Cherif Chefchaouni Ali , Lkhoyaali Sihame , Bechar Hafsa , Boudina Yassine , Abercha Youssef , Belahcen Mohammed Jaouad , Rahali Younes 
Published: December 2022

Introduction Tamoxifen is widely used for the treatment of hormone-responsive breast cancer. In this article, we report a case of a patient who developed hand deformities following long-term administration of tamoxifen. Case report A 57-year-old woman, followed for invasive ductal carcinoma of the left breast under tamoxifen for 7 years, presenting joint pain with deformities in her fingers. Management & outcome Following the appearance of the adverse effect, tamoxifen was stopped. A series of biologic and radiologic analysis were performed in order to explain the appearance of this event. A substitution treatment was discussed and a rheumatologist's opinion was requested. Discussion Tamoxifen appears to be associated with the development of inflammatory osteoarthritis resembling rheumatoid arthritis. Possible mechanisms of such an effect are discussed.
A review of medical devices used for safe chemotherapy applications: Focus on ONCOERA® IV GROUP products
Authors: Tekin Kemal , Karadoğan Muhammed , Kismet Kemal 
Published: December 2022

Objective The healthcare workers and the workers in the manufacturing industry of chemotherapy drugs are exposed to the “hazardous” effects of these drugs during production, transportation, distribution, administration, and disposal. In order to be protected from these harmful effects, personal protective equipment and medical devices providing safe applications are used. The aim of the present article is to review of medical devices used for safe chemotherapy applications in line with the information obtained from the literature. Data sources The international and national reliable sources, were used in the literature review for data analysis by using the keywords including chemotherapy, chemotherapy drugs, antineoplastic drugs, cytotoxic drugs, hazardous drugs, exposure to chemotherapy drugs, side effects of chemotherapy drugs, closed-system drug transfer devices, healthcare staff, needle-free devices, needle-free connectors, surface contamination, and phthalates. Data summary In order to minimize cytotoxic drug exposure, international standards were developed in the mid-1980s stating that all cytotoxic drugs should be prepared preferably in a ventilated biological safety cabinet, nurses dealing with the use of these drugs should use appropriate personal protective equipment, and in case of cytotoxic drug spillage, predefined cleaning and decontamination protocols should be followed. Although the risk of acute and long-term toxic effects in healthcare workers has decreased in recent years with these applications in the preparation and administration of cancer drugs, measurable contamination occurs in the workplace. A large number of medical devices have been developed for minimizing this type of contamination with chemotherapy drugs. In this article, these medical devices have been reviewed in detail under subtitles of closed system transfer devices, needle-free devices, and valve technology. Conclusions Until the results of the evaluations to be made in new studies prove the opposite, the use of these devices with additional protection measures taken, especially during the application of dangerous drugs, is of great importance in terms of patient and employee safety.
The Practice of Post-vaccination COVID-19 Prevention Strategy Among Healthcare Professionals in Felege Hiwot Referral Hospital, Northwest Ethiopia
Authors: Engdaw Garedew Tadege , Worede Eshetu Abera , Destaw Bitew Bikes 
Published: December 2022

Background: Coronavirus Disease 2019 (COVID-19) is an acute respiratory illness first discovered and identified in China. Countries are taking precautions to prevent COVID-19 in accordance with WHO guidelines. Objective: The objective of this study was to assess the practice of the COVID-19 prevention strategy post-vaccination and associated factors among health care professionals in Felege Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia, in 2021. Methods: An institutional-based cross-sectional study was carried out at Felege Hiwot Referral Hospital, Bahir Dar. Data were entered into Epi-Info software, version 7.1, and exported to SPSS, version 23, for analysis. Descriptive statistics were used to describe the socio-demographic characteristics of the respondents. The crude odds ratio (COR) and the adjusted odds ratio (AOR) with 95% CI were calculated to determine the coefficient of the COVID-19 prevention strategy. Results: In this study, 68.7% (95% CI: 63.7, 73.8) of health care professionals had good practice of the COVID-19 prevention strategy post-vaccination. Sex (AOR: 1.76; 95% CI: 1.08, 2.89), marital status (AOR: 1.75; 95% CI: 1.09, 2.93), and good attitude toward vaccination (AOR: 3.24; 95% CI: 2.13, 5.48) were significantly associated with the practice of COVID-19 prevention strategies post vaccination. Conclusions: The practices of COVID-19 preventive strategies post-vaccination were good among healthcare professionals. Good attitude toward vaccination, sex (male), marital status (married) were factors determining the occurrences of COVID-19 preventive strategies post-vaccination.
Traumatic injury patterns in humans from large feline predators: A systematic review and descriptive analysis
Authors: Kirtland Jack , Tremoleda Jordi L. , Trivedy Chetan 
Published: December 2022

Background Traumatic attacks from large feline predators cause a small yet significant burden of disease in rural populations, are increasing in frequency, cause complex injuries and worsen human–wildlife conflicts. Data on the traumatic injury pattern found in victims of these animals is sparse, and this study aimed to collate and synthesise patterns of injury to inform the care and management of these patients. Methods A multi-ethnographic literature search (PubMed, Embase, Web of Science, Google Scholar, and other sources) was performed on 12/1/21 to capture all available data describing anatomical injury and the mechanism of injury sustained by humans from attacks by lions, leopards and tigers. Quality and bias assessment was performed using the Joanna Briggs Critical Evaluation tools. Results Of 5110 studies identified, 42 were included in this review totalling 84 individual patient cases. A total of 85% of fatal injuries were due to exsanguination combined with neuroaxis injury of the neck. All wounds were susceptible to tissue loss, infection and long-term neuro-vascular complications. Leopards injured anterior-midline structures of the neck more often than did lions and tigers, while the latter caused high-energy fractures. Time lag to treatment for survivors of wild attacks extended to multiple days, and occult injury was common. Conclusion In addition to the primary finding of complex neck injury, this study generated specific patterns of injury seen from the included species and highlighted occult injury and healthcare disparity as challenges in providing patient care.
Initial PROMIS Scores Correlate With Operative and Nonoperative Management of Lateral Epicondylitis
Authors: Qiu Bowen , Sholtis Connor , Ketonis Constantinos 
Published: December 2022

Background: Lateral epicondylitis (LE) is a common source of elbow pain. Treatment options include physical therapy (PT), corticosteroid injection, or surgery, but the efficacy of each remains unclear. In this study, we compare Patient-Reported Outcomes Measurement Information System (PROMIS) scores between patients treated both operatively and nonoperatively for LE. Methods: Patients presenting to a tertiary academic medical center from February 2015 to December 2018 with a diagnosis of LE were identified. Those with initial and follow-up PROMIS physical function (PF), pain interference (PI), and Depression scores were included and stratified according to treatment. Single-factor analysis of variance testing was used to compare PROMIS scores between intervention types. Results: In all, 982 patients were initially identified with the diagnosis of LE and documented PROMIS scores. Initial treatment consisted of 266 patients receiving formal PT, 238 patients receiving injections, 20 patients undergoing surgery, and 296 patients receiving no formal treatment. At final follow-up, 235 (44.8%) patients had been treated with isolated PT, 237 (45.1%) with injections, and 52 (9.9%) with surgery. Patients who underwent formal PT had the highest initial PF scores when compared with all other interventions. Patients who underwent operative management had higher initial PI scores than those who pursued nonoperative management. Conclusions: Patient-Reported Outcomes Measurement Information System PF and PI may be useful for determining which treatment course patients suffering from LE are likely to pursue. Pain as a limiting factor in daily living may be a better indication for operative management as opposed to physical metrics.
A Comparison of the Rates of Postoperative Infection Following Distal Radius Fixation Between Pediatric and Young Adult Populations: An Analysis of 32 368 Patients
Authors: Albright J. Alex , Meghani Ozair , Rebello Elliott , Karim Omar , Testa Edward J. , Daniels Alan H. , Cruz Aristides I. 
Published: December 2022

Background: Infection following surgical fixation of a distal radius fracture can markedly compromise a patient’s functional outcome. This study aimed to compare infection rates in pediatric (5-14 years) and adolescent (15-17 years) patients undergoing fixation of a distal radius fracture to a cohort of young adult (18-30 years) patients. Methods: A matched retrospective study was performed using PearlDiver to determine the rates of postoperative infection following distal radius fixation. χ2 and logistic regression were used to assess differences in rates, while linear regression was used to analyze rates of infection over time. Results: In 32 368 patients, young adults experienced postoperative infection at a significantly increased rate (odds ratio [OR] = 1.81; 95% confidence interval [CI], 1.45-2.27). This trend was consistent among the male (OR = 1.96; 1.49-2.57) and female (OR = 2.11, 1.37-3.27) cohorts. In the multivariate model, the adult cohort remained at increased risk (OR = 1.40; 95% CI, 1.04-1.89), with open fracture (OR = 4.99; 3.55-6.87), smoking (OR = 1.76; 1.22-2.48), hypertension (OR = 1.69; 1.20-2.33), and obesity (OR = 1.37; 1.02, 1.80) identified as other significant risk factors. There was no significant change in the rate of postoperative infections over the 11-year study period. Conclusion: This study demonstrated that although surgical site infections following distal radius fixation are low in patients aged 30 years or younger (0.97%), young adults develop infections at a significantly increased rate. This is important for surgeons to recognize when counseling patients on the risks of surgical fixation.
Reliability and minimal detectable difference of pressure pain thresholds in a pain-free population
Authors: Koh Ryan GL , Paul Tracy M , Nesovic Karlo , West Daniel , Kumbhare Dinesh , Wilson Richard D 
Published: December 2022

The objective of this work was to evaluate the inter-rater and intra-rater reliability and minimal detectable difference (MDD) of pressure pain thresholds (PPTs) in pain-free participants with two examiners over two consecutive days in a cross-sectional study design. Examiners used a standardized method to measure and locate a specific testing site over tibialis anterior for PPT testing with a hand-held algometer. The mean of each examiner’s three PPT measurements was used to calculate the intraclass correlation coefficient, inter-rater reliability, and intra-rater reliability. The minimal detectable difference (MDD) was calculated. Eighteen participants were recruited (11 female). The inter-rater reliability was 0.94 and 0.96 on day 1 and day 2, respectively. Intra-rater reliability for the examiners was 0.96 and 0.92 on day 1 and day 2, respectively. The MDD on day 1 was 1.24 kg/cm2 (CI: 0.76–2.03) and the MDD on day 2 was 0.88 kg/cm2 (CI: 0.54–1.43). This study demonstrates high inter- and intra-rater reliability and the MDD values for this method of pressure algometry.