bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bifidobacteria define gut microbiome profiles of golden lion tamarin (Leontopithecus rosalia) and marmoset (Callithrix sp.) metagenomic shotgun pools
Authors: Malukiewicz Joanna , D’arc Mirela , Dias Cecilia A. , Cartwright Reed A. , Grativol Adriana D. , Moreira Silvia Bahadian , Souza Antonizete R. , Tavares Maria Clotilde Henriques , Pissinatti Alcides , Ruiz-Miranda Carlos R. , Santos André F. A. 
Published: September 2023

AbstractGut microbiome disruptions may lead to adverse effects on wildlife fitness and viability, thus maintaining host microbiota biodiversity needs to become an integral part of wildlife conservation. The highly-endangered callitrichid golden lion tamarin (GLT-Leontopithecus rosalia) is a rare conservation success, but allochthonous callitrichid marmosets (Callithrix) serve as principle ecological GLT threats. However, incorporation of microbiome approaches to GLT conservation is impeded by limited gut microbiome studies of Brazilian primates. Here, we carried out analysis of gut metagenomic pools from 114 individuals of wild and captive GLTs and marmosets. More specifically, we analyzed the bacterial component of ultra filtered samples originally collected as part of a virome profiling study. The major findings of this study are consistent with previous studies in showing thatBifidobacterium, a bacterial species important for the metabolism of tree gums consumed by callitrichids, is an important component of the callitrichid gut microbiome - although GTLs and marmosets were enriched for different species ofBifidobacterium. Additionally, the composition of GLT and marmoset gut microbiota is sensitive to host environmental factors. Overall, our data expand baseline gut microbiome data for callitrichids to allow for the development of new tools to improve their management and conservation.
The influence of general knowledge test performance on self-ratings of and perceived relationships between intelligence, knowledge, and memory
Authors: Coane Jennifer H. , Cipollini John , Beaulieu Charlotte , Song Julianna , Umanath Sharda 
Published: September 2023

AbstractThe present study examined how taking a general knowledge (GK) test affects perceptions of one’s intelligence, memory, and knowledge and the relationship between these three constructs. Participants rated their abilities on each construct and the strength of the relationships between them before and after completing an easy or hard GK test or control task. In Experiment 1, participants were (mis)informed that GK questions were correctly answered by 50% of the population; in Experiment 2, no such information was provided. Regardless of (mis)information about others’ performance, participants in the Hard condition believed they had a worse memory, were less knowledgeable, and were less intelligent post-task. However, the strength of the perceived relationship between GK and intelligence decreased only when participants were misled. Judgments of one’s intelligence, memory, and knowledge can be manipulated by taking a GK test, and individuals engage in self-protective behavior to reduce the potential threat to one’s self-concept.
Possible role of selenium in ameliorating lead-induced neurotoxicity in the cerebrum of adult male rats: an experimental study
Authors: Hegazy Abdelmonem Awad , Domouky Ayat M. , Akmal Fatma , El-wafaey Dalia Ibrahim 
Published: September 2023

AbstractChronic lead (Pb) poisoning is one of the greatest public health risks. The nervous system is the primary and most vulnerable target of Pb poisoning. Selenium (Se) has been shown to be a potential protection against heavy metal toxicity through anti-inflammatory and antioxidant properties. Therefore, the present study aimed to elucidate the possible protective role of Se in ameliorating the effects of Pb on rat cerebral structure by examining oxidative stress and markers of apoptosis. The rats were divided into 6 groups: control group, Se group, low Pb group, high Pb group, low Pb + Se group, high Pb + Se group. After the 4-week experiment period, cerebral samples were examined using biochemical and histological techniques. Pb ingestion especially when administered in high doses resulted in cerebral injury manifested by a significant increase in glial fibrillary acidic protein, malondialdehyde (MDA) marker of brain oxidation and DNA fragmentation. Moreover, Pb produced alteration of the normal cerebral structure and cellular degeneration with a significant reduction in the total number of neurons and thickness of the frontal cortex with separation of meninges from the cerebral surface. There was also a decrease in total antioxidant capacity. All these changes are greatly improved by adding Se especially in the low Pb + Se group. The cerebral structure showed a relatively normal histological appearance with normally attached pia and an improvement in neuronal structure. There was also a decrease in MDA and DNA fragmentation and an increase TAC. Selenium is suggested to reduce Pb-induced neurotoxicity due to its modulation of oxidative stress and apoptosis.
A low dimensional embedding of brain dynamics enhances diagnostic accuracy and behavioral prediction in stroke
Authors: Idesis Sebastian , Allegra Michele , Vohryzek Jakub , Sanz Perl Yonatan , Faskowitz Joshua , Sporns Olaf , Corbetta Maurizio , Deco Gustavo 
Published: September 2023

AbstractLarge-scale brain networks reveal structural connections as well as functional synchronization between distinct regions of the brain. The latter, referred to as functional connectivity (FC), can be derived from neuroimaging techniques such as functional magnetic resonance imaging (fMRI). FC studies have shown that brain networks are severely disrupted by stroke. However, since FC data are usually large and high-dimensional, extracting clinically useful information from this vast amount of data is still a great challenge, and our understanding of the functional consequences of stroke remains limited. Here, we propose a dimensionality reduction approach to simplify the analysis of this complex neural data. By using autoencoders, we find a low-dimensional representation encoding the fMRI data which preserves the typical FC anomalies known to be present in stroke patients. By employing the latent representations emerging from the autoencoders, we enhanced patients’ diagnostics and severity classification. Furthermore, we showed how low-dimensional representation increased the accuracy of recovery prediction.
Morphological, pathogenic and genetic diversity in Diplodia seriata associated with black rot canker of apple in India
Authors: Bhat Arif Hussain , Shah M. D. , Padder B. A. , Shah Zahoor Ahmad , Dar Eajaz Ahmad , Fayaz U. , Nain Manjeet Singh , Ali M. Ajmal , Al-Hemaid Fahad M. , Stępień Piotr , Ahmed Mohamed A. A. , Salama Ehab A. A. 
Published: September 2023

AbstractApple cankers are extremely destructive diseases threatening the global apple industry through direct and indirect losses. The population structure of the pathogens is of paramount significance for the development of efficient management strategies. Therefore, phenotypic, pathogenic, and genetic diversity of Diplodia seriata causing black rot canker of apple was investigated in this study. All the isolates were included for investigating the in vitro mycelial growth, conidial dimensions, and pathogenic variability on two-year-old potted apple seedlings. The ISSR approach was used to investigate the molecular diversity of D. seriata. Mycelial growth rates were found to vary significantly amongst the isolates; however, there were no major variations seen between the different geographical groupings of isolates. Pathogenicity tests revealed variations in the size of cankers among the isolates indicating the presence of virulence variability. The isolates were segregated into three virulence groups based on canker length. The Bayesian analyses of ISSR data divided the isolates into two genetic clusters. The genetic clustering of the isolates revealed no relationship with geographical origin of the isolates. Furthermore, no direct relationship of genetic clustering was observed with morphological or pathogenic variability. The ISSR primers revealed very high level of variability in D. seriata; however, no distinct populations of the pathogen existed which is an indication of high level of gene flow between the diverse geographical populations. According to our knowledge, this is the first thorough investigation on the diversity of D. seriata associated with apple black rot canker in India.
MHD dissipative Powell-Eyring fluid flow due to a stretching sheet with convective boundary conditions and slip velocity
Authors: Abbas W. , Megahed Ahmed M. , Emam M. S. , Sadek Hassan M. H. 
Published: September 2023

AbstractThe novelty and motivation of this research can be emphasized by examining how the heat transfer mechanism of a non-Newtonian Powell-Eyring fluid, which flows because of a stretched sheet, is affected by factors like viscous dissipation, the slip velocity phenomenon, and Joule heating. In addition, the investigation delves into the heat transfer behavior of the fluid flow when it comes into contact with a convectively heated stretched surface that is influenced by varying fluid properties. This analysis also takes into account the influence of changing fluid characteristics and the presence of magnetic field. The numerical solutions of modelled equations that governing the problem are detected using the shooting technique. Also, in order to confirm the validity of the present investigation, a proper comparison with certain published works as a particular case of the present model is presented, and a perfect agreement is noted. With the use of diagrams and tables, the flow problem’s effective parameters are thoroughly discussed. Likewise, through a tabular representation, the values of the local Nusselt number and the skin-friction coefficient are computed and analyzed. Many significant conclusions can be drawn from numerical results. Most importantly, the local Nusselt number rises monotonically with both the surface convection parameter and the slip velocity parameter, but the local skin-friction coefficient has the opposite trend. The results indicate that the nanofluid temperature is enhanced by factors such as the surface convection parameter, magnetic field, and viscous dissipation. On the other hand, the slip velocity phenomenon leads to the opposite effect.
Regulation of straw decomposition and its effect on soil function by the amount of returned straw in a cool zone rice crop system
Authors: Liu Lin , Cheng Ming , Yang Lei , Gu Xinyue , Jin Jingyi , Fu Minjie 
Published: September 2023

AbstractThe degradation process of returned straw in rice fields can improve soil organic matter and promote sustainable agriculture. The degradation process of returned straw is a humification process as well as a mineralization process involving microorganisms and enzymes. However, the degradation process of returned straw, the effect on straw decomposing microorganisms and the regulatory mechanism on potential functionality under cool climate flooding conditions are currently unknown.For this purpose, we investigated the biodegradation of straw from a biodegradation point of view at 20, 40, 71, 104, and 137 d after return under conventional (130 kg hm−2), 1/3 straw return (2933 kg hm−2), 2/3 straw return (5866 kg hm−2), and full straw return (8800 kg hm−2) applications in cool climate rice fields.. The test found Paludibacteraceae and Archaeaceae were the dominant bacteria for straw degradation, and their relative abundance was highest when 2/3 of straw was returned to the field. The straw degradation extracellular enzyme activity was higher in the late return period (104 d). At this time, the potential functionality of the soil differed significantly among the different return amounts, with the best extracellular enzyme activity and potential functionality at the 2/3 straw return amount. Therefore, the optimal amount of rice straw returned to the field is 5866 kg hm−2 at the current conventional N application rate (130 kg hm−2) in the cold zone.
High care and low overprotection from both paternal and maternal parents predict a secure attachment style with a partner among perinatal Japanese women
Authors: Zain Ekachaeryanti , Fukui Naoki , Watanabe Yuichiro , Hashijiri Koyo , Motegi Takaharu , Ogawa Maki , Egawa Jun , Someya Toshiyuki 
Published: September 2023

AbstractThis study aimed to determine how paternal and maternal parenting before adolescence affects adult attachment to a partner during the perinatal period, using three different models of attachment. We used the Parental Bonding Instrument (PBI) and the Relationship Questionnaire (RQ) to examine perceived parenting practices and adult attachment styles, respectively. The participants included 4586 Japanese women who were pregnant or who had given birth, up until one month after childbirth. We performed structural equation modeling analysis between PBI and RQ scores with three different category models, including the four-category model (secure, fearful, preoccupied, and dismissive attachment) as Model 1, the two-category model (model of the self and others) as Model 2, and the single-category model (total attachment style) as Model 3. Models 1 and 2 showed a good fit. Both path models showed a significant association between adult attachment style and perceived paternal and maternal parenting before adolescence, where high care and low overprotection from both paternal and maternal parents predicted adult attachment. Our findings indicate that attachment styles are best described using the four-category and two-category models, and suggest that both paternal and maternal overprotection and care influence adult attachment with a partner during the perinatal period.
Ameliorative effects of aerobic training in girls with precocious puberty: role of leptin and ghrelin
Authors: Najafi Ramyar , Heidarianpour Ali , Shokri Elnaz , Shokri Behnaz 
Published: September 2023

AbstractThis study was an attempt to examine the changes in serum levels of ghrelin and leptin after 12-weeks of aerobic training and gonadotropin releasing hormone agonist (GnRH) treatment in girls with central precocious puberty. Thirty girls (6–8 years old) with precocious puberty who had received Triptorelin were randomly divided in two groups (medication and medication + training). Fifteen age-matched healthy girls (without precocious puberty) were also included as the control group. The medication + training group submitted an aerobic training program for 3 days/week with 20–75 min per day and 45–75% of maximum heart rate for 12-weeks. Serum levels of leptin, ghrelin, cholesterol, triglycerides and body mass index (BMI) were determined at baseline and 48 h after the last training session. The results indicated that leptin significantly decreased (p = 0.001) and ghrelin significantly increased (p = 0.001) in the medication + training group but no significant difference was observed in the ghrelin (p = 1) and leptin (p = 0.78) in the medication group. Leptin to ghrelin ratio indicated a decrease in medicine + training group (p = 0.028). Ghrelin were negatively correlated with leptin and BMI. The data indicated that aerobic training increased ghrelin and reduced leptin and leptin to ghrelin ratio but GnRH agonist treatment had no effect on plasma leptin and ghrelin levels.
Prevalence and characteristics of pain in moderate-to-severe obstructive sleep apnea patients and effect of CPAP treatment
Authors: Shen Chong , Ou Yanru , Ouyang Ruoyun , Zong Dandan 
Published: September 2023

AbstractPain problems are common in patients with obstructive sleep apnea (OSA), but few studies have thoroughly evaluated pain in these patients. The objective of this study was to examine the prevalence and characteristics of pain in moderate-to-severe OSA patients and the effect of continuous positive airway pressure (CPAP) treatment. Moderate-to-severe OSA patients and healthy controls (HC) completed the Short Form McGill Pain Questionnaire (SF-MPQ) and a portion of the Brief Pain Inventory (BPI) Short Form to assess pain characteristics. The Epworth Sleepiness Scale (ESS), the Short Form-36 (SF-36), and the Hospital Anxiety and Depression Scale (HADS) were used to measure daytime sleepiness, health-related quality of life (HRQoL), and psychological status, respectively. The OSA patients with pain were divided into a CPAP-treated group and a CPAP-untreated group based on their adherence to CPAP. The subjects' pain intensity was reassessed after 3 months. The prevalence of pain was 57.5% in OSA versus 27.1% in HC (p < 0.001). Head (39.0%) accounted for the highest proportion of overall pain locations in subjects with OSA, with 28.8% of OSA patients experiencing headaches. Pain in OSA was associated with impaired HRQoL and psychological problems. Patients with very severe OSA had an increased risk for pain problems (OR: 7.000, p = 0.041). Associated factors for pain intensity in OSA included age, ESS ≥ 9.0, and lowest pulse oximetry (LSpO2) < 80.0%. Pain intensity in OSA decreased significantly after CPAP treatment (p < 0.001). Pain was prevalent among patients with moderate-to-severe OSA and was associated with depression, anxiety, and a lower HRQoL. Patients with very severe OSA had an increased risk for pain problems. The intensity of pain in OSA can be predicted by age, ESS ≥ 9.0, and LSpO2 < 80.0%, and it can be alleviated through CPAP treatment.
The influence of natural variability on extreme monsoons in Pakistan
Authors: Ashfaq Moetasim , Johnson Nathaniel , Kucharski Fred , Diffenbaugh Noah S. , Abid Muhammad Adnan , Horan Matthew F. , Singh Deepti , Mahajan Salil , Ghosh Subimal , Ganguly Auroop R. , Evans Katherine J. , Islam Shafiqul 
Published: September 2023

AbstractThe monsoons in Pakistan have been exceptionally harsh in recent decades, resulting in extraordinary drought conditions and record flooding events. The changing characteristics of extreme events are widely attributed to climate change. However, given this region’s long history of floods and droughts, the role of natural climate variability cannot be rejected without a careful diagnosis. Here, we examine how oceanic and atmospheric variability has contributed to unusual precipitation distributions in West South Asia. Variations in sea surface temperatures in the tropical Pacific and northern Arabian Sea, and internal atmospheric variability related to the circumglobal teleconnection pattern and the subtropical westerly jet stream, explain more than 70% of monthly summer precipitation variability in the 21st century. Several of these forcings have co-occurred with record strength during episodes of extreme monsoons, which have exacerbated the overall effect. Climate change may have contributed to increased variability and the in-phase co-occurrences of the identified mechanisms, but further research is required to confirm any such connection.
W546 stacking disruption traps the human porphyrin transporter ABCB6 in an outward-facing transient state
Authors: Lee Sang Soo , Park Jun Gyou , Jang Eunhong , Choi Seung Hun , Kim Subin , Kim Ji Won , Jin Mi Sun 
Published: September 2023

AbstractHuman ATP-binding cassette transporter subfamily B6 (ABCB6) is a mitochondrial ATP-driven pump that translocates porphyrins from the cytoplasm into mitochondria for heme biosynthesis. Within the transport pathway, a conserved aromatic residue W546 located in each monomer plays a pivotal role in stabilizing the occluded conformation via π-stacking interactions. Herein, we employed cryo-electron microscopy to investigate the structural consequences of a single W546A mutation in ABCB6, both in detergent micelles and nanodiscs. The results demonstrate that the W546A mutation alters the conformational dynamics of detergent-purified ABCB6, leading to entrapment of the transporter in an outward-facing transient state. However, in the nanodisc system, we observed a direct interaction between the transporter and a phospholipid molecule that compensates for the absence of the W546 residue, thereby facilitating the normal conformational transition of the transporter toward the occluded state following ATP hydrolysis. The findings also reveal that adoption of the outward-facing conformation causes charge repulsion between ABCB6 and the bound substrate, and rearrangement of key interacting residues at the substrate-binding site. Consequently, the affinity for the substrate is significantly reduced, facilitating its release from the transporter.
Pesticide reduction amidst food and feed security concerns in Europe
Authors: Schneider Kevin , Barreiro-Hurle Jesus , Rodriguez-Cerezo Emilio 
Published: September 2023

AbstractRecent studies have estimated the potential yield impacts of pesticide reductions in the European Union. While these estimates guide policy design, they are often based on worst-case assumptions and rarely account for positive ecological feedbacks that would contribute to sustainable crop yields in the long term.
Multi‐source to multi‐target domain adaptation method based on similarity measurement
Authors: Wu Lan , Wang Han , Yao Yuan 
Published: September 2023

AbstractMost existing domain adaption methods solve the problem of data distribution similarity in single‐source to single‐target domain or multi‐source to single‐target domain adaption, but the more realistic multi‐source to multi‐target domain transfer scenarios are ignored. At the same time, less attention is paid to the similarity of task distribution among domains and the corresponding relationship between coarse‐grained and fine‐grained, which leads to the problem of low classification accuracy. In this paper, a multi‐source to multi‐target domain adaption (MSMTDA) method based on similarity measurement is proposed. Firstly, a cross‐domain similarity measurement mechanism based on the idea of data distribution similarity and task distribution similarity is set up to judge and optimize the distribution difference among source domains and target domains. Secondly, global‐local‐bidirectional alignment is used to solve the problem of poor transfer performance in the existing distributed alignment. Then, the cross‐domain mutual learning strategy is proposed, which reduces classifier discrepancy caused by decision boundaries and distribution difference in multiple domains. Finally, the proposed method is verified on three benchmark datasets in image classification. The experimental results show that the proposed method performs better in both classification accuracy and training time when compared with the conventional method.
Pix2PixSSR: Spatial super‐resolution synthesis and visualization for time‐varying volumetric data
Authors: Ma Ji , Chen Jinjin 
Published: September 2023

AbstractUpscaling of the time‐varying volume data is significant, since it can be used in in situ visualization to help scientists fast analyse complex simulations relevant to time‐varying volume data. A novel deep learning method called Pix2Pix spatial super‐resolution (Pix2PixSSR), which can be used to generate spatial super‐resolution of the time‐varying volume data is proposed here. It consists of two main components: One is a variant UNet‐like generator that takes the low resolution volume sequence as input and generates the high resolution counterparts; one is a PatchGAN discriminator that takes both low and high resolution volume sequences as input and predicts their realness. To validate its advantages, we qualitatively and quantitatively compare it with the state‐of‐the‐art upscaling techniques. More specifically, two experiments are performed. The first experiment uses the same variable of a time‐varying volume dataset for training and inference, while the second experiment uses different variables for training and inference. The experimental results show that for most cases, the Pix2PixSSR can generate the most similar super‐resolution to the ground truth, compared to the state‐of‐the‐art techniques.