bluuebunny/crossref_metadata_2025_split huggingface dataset:
Transcriptome analyses of mouse cardiac myocytes and non-cardiomyocytes: postmitotic vs. proliferative cells
Authors: Takenaka Yasuhiro , Hirasaki Masataka , Inoue Ikuo , Ikeda Masaaki , Ohata Hisayuki , Kakinuma Yoshihiko 
Published: August 2023

AbstractAdult heart mostly contains long-lived postmitotic cardiomyocytes and non-cardiomyocytes that have proliferative potential. Here, we isolated cardiomyocytes and non-cardiomyocytes from young and aged mouse heart, and performed transcriptome analyses by RNA sequencing to understand the differences of gene expression in postmitotic and proliferative cells. Gene ontology analyses revealed that genes associated with inflammatory response were upregulated in aged cardiac myocytes, whereas genes including two ATP synthases in mitochondrial respiratory complex V (Atp5landAtp5J2) and two NADH dehydrogenases in complex I (Ndufa11andNdufv3) were significantly downregulated. In aged non-cardiomyocytes, genes related to inflammatory responses were also upregulated, while genes involved in cell cycle and DNA replication process were downregulated. We also found that the expression levels of some small nucleolar RNAs (snoRNAs) are decreased cardiomyocytes with aging. snoRNAs are deeply involved in RNA modification such as pseudouridylation stabilizing ribosomal RNA (rRNA) and mRNA splicing. Therefore, the age-related reduction in snoRNA expression may lead to the destabilization of rRNA, splicing dysfunction, and ultimately a decrease in protein synthesis capacity. A comparison with transcriptome results obtained for non-cardiomyocytes suggests that the decline in the expression of mitochondria-related genes and snoRNAs accompanying aging is specific to cardiomyocytes, implying their potential utility as one of novel aging markers in postmitotic cells.
Red light perception by the root is essential for gibberellin-induced primary-root elongation in tomato
Authors: Ramon Uria , Adiri Amit , Cheriker Hadar , Nir Ido , Burko Yogev , Weiss David 
Published: August 2023

SummaryThe promoting effect of gibberellin (GA) on primary-root elongation is well-documented in several plant species, yet its influence in others, including tomato (Solanum lycopersicum), remains unclear.The role of GA in primary-root elongation has been studied in tomato using the GA-deficient mutantsgib-1andga20-oxidase(ga20ox1) and various growth systems, including Dark (D)-root and D-shoot plates.GA application to these mutants following germination on vermiculite, promoted primary-root elongation. However, when the roots grew deeper into the dark environment the hormone had no effect. RNA-seq analysis of dark-grown roots, treated with GA, revealed typical transcriptional responses, but the output for cell expansion remained unaffected. When dark-grown roots were illuminated deep in the ground, the hormone promoted their elongation. The results suggest that activation of Phytochrome B (PhyB) in the root, by red light, is essential for GA-induced elongation.We propose that GA promotes tomato root elongation after germination, when roots are exposed to low light underground and this contributes to rapid seedling establishment. As roots penetrate deeper into the soil, insensitivity to GA due to the lack of light may be important for sustained root growth under fluctuating water availability, given that water deficiency suppresses GA accumulation.
Synthesis and characterization of DOE-based stir-cast hybrid aluminum composite reinforced with graphene nanoplatelets and cerium oxide
Authors: Kumar Dinesh , Angra Surjit , Singh Satnam 
Published: August 2023

Purpose
This research outlines the development and characterization of advanced composite materials and their potential applications in the aerospace industry for interior applications. Advanced composites, such as carbon-fiber-reinforced polymers and ceramic matrix composites, offer significant advantages over traditional metallic materials in terms of weight reduction, stiffness and strength. These materials have been used in various aerospace applications, including aircraft, engines and thermal protection systems.

Design/methodology/approach
The development of design of experiment–based hybrid aluminum composites using the stir-casting technique has further enhanced the performance and cost-effectiveness of these materials. The design of the experiment was followed to fabricate hybrid composites with nano cerium oxide (nCeO2) and graphene nanoplatelets (GNPs) as reinforcements in the Al-6061 matrix.

Findings
The Al6061 + 3% nCeO2 + 3% GNPs exhibited a high hardness of 119.6 VHN. The ultimate tensile strength and yield strength are 113.666 MPa and 73.08 MPa, respectively. A uniform distribution of reinforcement particulates was achieved with 3 Wt.% of each reinforcement in the matrix material, which is analyzed using scanning electron microscopy. Fractography revealed that brittle and ductile fractures caused the failure of the fractured specimens in the tensile test.

Practical implications
The manufactured aluminum composite can be applied in a range of exterior and interior structural parts like wings, wing boxes, motors, gears, engines, antennas, floor beams, etc. The fan case material of the GEnx engine (currently using carbon-fiber reinforcement plastic) for the Boeing 7E7 can be another replacement with manufactured hybrid aluminum composite, which predicts weight savings per engine of close to 120 kg.

Originality/value
The development of hybrid reinforcements, where two or more types of reinforcements are used in combination, is also a novel approach to improving the properties of these composites. Advanced composite materials are known for their high strength-to-weight ratio. If the newly developed composite material demonstrates superior properties, it can potentially be used to replace traditional materials in aircraft manufacturing. By reducing the weight of aircraft structures, fuel efficiency can be improved, leading to reduced operating costs and environmental impact. This allows for a more customized solution for specific application requirements and can lead to further advancements in materials science and technology.
Postgraduate students’ internet use and prevalence of internet addiction: what roles can librarians play post COVID-19?
Authors: Salubi Oghenere Gabriel , Muchaonyerwa Ndakasharwa 
Published: August 2023

Purpose
This study empirically analyse the lived and individual experiences of internet use time among postgraduate students in a period where the line between the virtual and real is blurred. The infusion of the internet in higher education has not only facilitated the production of new knowledge but has also led to reports of internet addiction among many users during the COVID-19 pandemic and the resulting lockdowns. This study aims to evaluate the level of internet addiction among postgraduate students and the supportive information services role that librarians could provide.

Design/methodology/approach
In this study, 279 postgraduate students completed a quantitative survey targeted at all the postgraduate students at a university campus in South Africa. Data was collected using an adopted internet addiction test questionnaire. The data was descriptively and inferentially analysed.

Findings
As many as 61 (22.7%) are always online, with most of the respondents, 112 (41.6%) spend 10 h or more on the internet daily. Laptop computers at 44.7% emerged as the primary electronic device used by postgraduate students for accessing the internet, surpassing the prevalence of mobile phone usage. On internet addiction level, internet use time had a statistically significant relation with problematic internet use levels in respondents. These results suggest that the increased uncontrolled internet use could negatively interfere with productive academic work of postgraduate students. However, based on the inferential statistical results, it can be concluded that academic use of the internet does not contribute to increased levels of internet addiction. The study recommends that librarians should provide literacy education and resources on how to use the internet safely and responsibly, including tips on setting boundaries, managing time online and productively using online information resources.

Originality/value
The study assesses problematic internet use among postgraduate students and provides suggestions on supportive information services that librarians could provide in an era where many library information services provision and higher education are hinged on the internet.
Cotton Web Limited: a journey from disintegrated complaint handling to an efficient and robust e-complaint management system
Authors: Shuja Aleena , Awan Malik Imtiaz , Saleem Imran 
Published: August 2023

Learning outcomes
The purpose of this study is to make students understand the logic behind and implications of the “Socio-Technical Imbrication Framework” that can help them understand the importance of aligning workforce motivation and capabilities with the modern technology deployed in the organization. Moreover, students will understand the essentiality and criticality of customer satisfaction for the organization.

Case overview/synopsis
The technical services operations team at Cotton Web Limited formerly relied on JS Node, e-coordination system, to address customer complaints. There were many bugs in that system as it did not carry along the complaint tracking protocol, was slow in response, fundamentally structured upon manual complaint record keeping that resulted in piling up un-resolved complaints for a longer period of time. The team under the leadership of Mr. Hasan Ali, a competent expert working as GM Research and Data Analytics, undertook detailed analysis of recurring glitches in this system and replaced it with a novel Web-based automated complaint management system at Cotton Web Limited. This entire diagnosis and intervention process took almost three months till completion. The case is written for use in courses in the curriculum of BBA, BBIS, BSIT and BSCS programs at undergraduate level. It is most suitable for the courses in leadership, change management, business process reengineering, soft engineering, team building and business communication.

Complexity academic level
The case is suitable for teaching at Undergraduate level to the students of BBIS, BBA, BSCS and BSIT students in the last year of their degree programs. Teaching faculty can use case-based methodology for student learning by putting them into a real-life situation faced by an organization and letting them think critically and identify following points for further discussion and clarity: individual or in groups; problem identification through discussion; the stakeholders involved in the company’s situation through presentation or one-pager presentation; case analysis with reaching best solution to prevailing issue at hand through group discussion; reaching a decision or solution with reasonable logic and justification through group discussions; and create further dilemma on the basis of questions unanswered within this case story.

Supplementary material
Teaching notes are available for educators only.

Subject code
CSS 7: Management Science.
Evaluation of the comprehensive thematic teaching effectiveness and technique/technology in culinary vocational education
Authors: Ma Chia-Yen , Wang Kuo-Ching , Liu De-Yen , Lai Ting-Ching 
Published: August 2023

PurposeThe research aims to discuss technical and vocational students' long-term and complete evaluation of learning effectiveness under school-wide thematic teaching design.Design/methodology/approachThis study adopted a mixed qualitative and quantitative approach to measure the learning effectiveness of thematic teaching in technical vocational schools using the Kirkpatrick model. Qualitative research conducted in-depth interviews with 32 interviewees, including students, parents, teachers, graduate alumni and the supervisors of off-campus internship units. Quantitative research conducted a questionnaire survey on vocational students. A total of 221 valid questionnaires were collected. In addition, this research conducts another quantitative survey on cooperative enterprises to compare the actual effect of the implementation of the school-wide thematic teaching students with the others, and a total of 35 valid questionnaires were collected.FindingsThe results of the research found that the effectiveness of thematic teaching method can achieve the expected goals of each level of Kirkpatrick model. The students taking thematic teaching are significantly better and fitting in the industry expects. Therefore, this research suggests the comprehensive introduction of school-wide thematic teaching to other school operators.Originality/valueThis research is the first study used the Kirkpatrick model to evaluate the effectiveness of school-wide thematic teaching design in hospitality education and providing a practical case for schools. This research combined qualitative and quantitative research methods to investigate the effectiveness of the teaching method through multiple perspectives. Through the feedback from supervisors of the hospitality industry, the school-wide thematic teaching design provides a good foundation for technical and vocational graduates.
Effect of social media usage on major depressive disorder among generation Z: a study in Indian context
Authors: Bhat Ishfaq Hussain , Gupta Shilpi , Bhat Ghulam Mohammad 
Published: August 2023

Purpose
The purpose of this study is to examine the specific social media behaviours (SMB) that lead to major depressive disorder (MDD). The study also looks at the moderation effect of pandemic on social media usage among users.

Design/methodology/approach
Using a descriptive approach, the required data was collected from a sample of 629 social media users chosen through random sampling technique. An adopted structured online questionnaire was used to collect the data. The data collected was analysed by using univariate and multinomial regression techniques.

Findings
The findings of the study revealed that social media intensity, social media addiction (SMA), social media participation, social interaction and SMB had a positive impact on MDD, whereas social comparison had a negative impact. The pandemic situation has also been found to moderate the effect of social media usage on MDD.

Social implications
This study will be supportive in disclosing behaviours and activities of students that impact their mental health adversely. This will also be helpful in dealing with specific stressors in the programs designed to cope with the depression. By adopting effective strategies to manage social media usage, the study would help to reduce the level of depressive symptoms among college students, significantly promoting healthy environments for students and, thus, contribute to social change.

Originality/value
Since the social media has both favourable and detrimental effects, the key for the users is to develop an awareness about the wise usage and to determine the alterations in the usage patterns that can help to reduce the behaviours associated with negative emotions and psychological distress.
Environmentalism in photovoltaics substitution, nationalism in photovoltaics rivalry and youth’s choice of solar power banks in Lanzhou
Authors: Zha Yiru , Jin Jiawei 
Published: August 2023

Purpose
This study aims to investigate how environmentalism in photovoltaic (PV) substitution and nationalism in PV rivalry with the USA are associated with the trade-offs made by young consumers in Lanzhou when selecting Chinese brand portable solar power banks.

Design/methodology/approach
In this study, the choice-based conjoint survey was conducted to investigate mobile power bank consumers aged 18–28 in Lanzhou urban districts. A total of 2,004 valid questionnaires were collected and 1,813 sample was used in analyses. Logit and ordinary least squares regression models were run for empirical analyses.

Findings
The research results show that consumers tend to sacrifice certain levels of affordability for moderate technological capability, a reputable brand, better portability and advanced charging functions or sacrifice certain levels of technological capabilities for a moderate price. Consumers with stronger environmentalism in PV substitution tend to prioritize median price levels, larger battery capacity and better portability, while being less sensitive to brand and showing less preference for advanced charging functions. Consumers with stronger nationalism in PV rivalry tend to prioritize reasonably higher prices, bigger brands, enhanced portability, more solar panels and advanced charging functions.

Practical implications
This research sheds light on consumer trade-offs between price, brand, portability, technological capability and charging function. It also explores how environmentalism and nationalism sentiments are associated with consumer decision-making. These insights carry valuable policy implications for fostering product innovation, supporting brand-building initiatives for small and medium-size enterprises, promoting market competition and preventing the weaponization of consumer nationalism.

Originality/value
As an emerging solar power product, the portable solar power bank holds significant potential for widespread adoption as a means to drive energy transition. Within the current context, two notable sentiments have surfaced: environmentalism, which pertains to the adoption of PV technology as a substitute for conventional energy sources and nationalism, which manifests in the PV rivalry between China and the USA. This research aims to investigate consumer preference related to this emerging product, specifically focusing on its relationship with these two sentiments.
Toyota Kata for continuous improvement; an action research project in the construction industry
Authors: Lodgaard Eirin , Iakymenko Natalia , Mogos Maria Flavia 
Published: August 2023

Purpose
The purpose of this study is to investigate how Toyota Kata can be effectively applied in the engineer-to-order (ETO) manufacturing within the construction industry. The objective is to identify the critical success factors (CSFs) for the Toyota Kata implementation in this environment and to develop a continuous improvement (CI) method – based on Toyota Kata and adapted to the ETO manufacturing within the construction industry.

Design/methodology/approach
An action research (AR) approach was applied, which includes a participatory form of inquiry and learning from both intended and unintended outcomes, while simultaneously building up scientific knowledge about successful implementation of Toyota Kata.

Findings
All the CSFs in the AR project are addressed by the earlier literature, thus confirming the existing body of knowledge. Moreover, the existing knowledge was arguably extended through the modified Toyota Kata as an approach for CI. New elements regarding how to run the small experiments by extending the core team with personnel who work with the problem on a daily basis.

Originality/value
This research addresses a gap identified in the literature regarding how Toyota Kata can be adapted to the ETO manufacturing within the construction industry. It also presents an overview of CSFs for the Toyota Kata implementation in this environment.
Properties of mortar containing Phragmites Australis Ash
Authors: Khatib Jamal , ElKhatib Lelian , Assaad Joseph , El Kordi Adel 
Published: August 2023

Purpose
The purpose of this paper is to examine the use of phragmites australis ash (PAA) in cementitious systems to achieve sustainable construction.

Design/methodology/approach
In this paper, the properties of mortar containing PAA as partial cement replacement are determined. The PAA is produced through slow burning in a closed system to minimize the CO2 emission. A total of four mortar mixes are prepared with PAA replacement levels ranging from 0% to 30% by weight. The water to binder and the proportions of binder to sand are 0.55 and 1:3 by weight, respectively. The properties tested are density, compressive strength, flexural strength, ultrasonic pulse velocity, water absorption by total immersion and capillary rise. Testing is conducted at 1, 7, 28 and 90 days.

Findings
While there is a decrease in strength as the amount of PAA increases, there is strong indication of pozzolanic reaction in the presence of PAA. This is in agreement with the results reported by Salvo et al. (2015), where they found noticeable pozzolanic activities in the presence of straw ash, which is rich in SiO2 and relatively high K2O content. At 90 days of curing, there is a decrease of 5% in compressive strength at 10% PAA replacement. However, at 20% and 30% replacement, the reduction in compressive strength is 23% and 32%, respectively. The trend in flexural strength and ultrasonic pulse velocity is similar to that in compressive strength. The water absorption by total immersion and capillary rise tends to increase with increasing amounts of PAA in the mix. There seems to be a linear relationship between water absorption and compressive strength at each curing age.

Research limitations/implications
The Phragmites australis plant used in this investigation is obtained from one location and this present a limitation as the type of soil may change the properties. Also one method of slow burning is used. Different burning methods may alter the composition of the PAA.

Practical implications
This outcome of this research will contribute towards sustainable development as it will make use of the waste generated, reduce the amount of energy-intensive cement used in construction and help generate local employment in the area where the Phragmites australis plant grows.

Originality/value
To the best knowledge of the authors, the ash from the Phragmites australis plant has not been used in cementitious system and this research can be considered original as it examines the properties of mortar containing PAA. Also, the process of burning in a closed system using this material.