bluuebunny/crossref_metadata_2025_split huggingface dataset:
Magnetic resonance imaging assessment of the therapeutic effect of combined electroacupuncture and stem cells in acute peripheral nerve injury
Authors: Chen Yueyao , Pan Zhongxian , Meng Fanqi , Yu Xuewen , Xu Qian , Huang Leyu , Liang Qiumei , Wu Yanglei , Lin Xiaofeng 
Published: December 2022

Objectives: This study aimed to evaluate the therapeutic effect of a combination of Bone Mesenchymal stem cells (BMSCs) transplantation and Electroacupuncture (EA) for acute sciatic nerve injury in rats using magnetic resonance.Methods: Ninety-two male adult healthy Sprague-Dawley rats were randomly divided into the EA+BMSCs group, EA group, MSCs group, and PBS group (control). Electroacupuncture was performed on a rat receiving EA treatment at Huantiao (GB30) and Zusanli (ST36). T2 values and diffusion tensor imaging (DTI) derived from multiparametric magnetic resonance imaging (MRI), histological assessments, and immunohistochemistry was used to monitor nerve regeneration. Walking track analysis was used to assess nerve functional recovery. Repeated-measures one-way analysis of variance was used to evaluate the significance of T2, DTI, and SFI values among the four groups. One-way analysis of variance was used for comparing the histological characteristics. Bonferroni test was used for multiple pairwise comparisons at each time point.Results: In terms of FA, the EA+BMSCs and EA groups had faster recovery than PBS (control) in all time points after surgery, and the EA+BMSCs group recovered better than the BMSCs group at 3 weeks (P ≤ 0.008). FA values were higher in the EA group than in the BMSCs group at 4 weeks (P ≤ 0.008). In terms of RD, the EA+BMSCs group recovered better than the BMSCs group at 2 and 4 weeks (P ≤ 0.008). Immunofluorescence staining for axon guidance molecule netrin-1 revealed that it was significantly higher in the EA+BMSCs subgroup and EA subgroup than it was in the control (PBS) subgroup at 1–3 weeks (P &lt; 0.001). Immunofluorescence staining for S100 showed the continuity of nerve fibers recovered more quickly in the EA+BMSCs subgroup than in the BMSCs subgroup.Conclusion: Our research revealed that a combination of MSCs and EA can provide both topological and biomolecular guidance to promote axonal extension, myelin regeneration, and functional recovery after PNI. EA not only promotes nerve repair on its own, but also enhanced the beneficial effects of stem cell treatment and the secretion of netrin 1, a guidance regeneration factor, and promotes the orderly growth of nerve fibers. These PNI repairs could be monitored non-invasively and in situ by MRI. The FA and RD values derived from MRI could be sensitive biomarkers to reflect the PNI repair process.
The clinical significance of peripheral blood cell ratios in patients with intracranial aneurysm
Authors: Kim Hyun Kyung , Lee Kee Ook , Oh Seung-Hun , Lee Kyung-Yul , Choo Seung-Wook , Kim Ok Joon , Kim Tae Gon , Kim Sang-Heum , Na Sang-Jun , Heo Ji Hoe 
Published: December 2022

Background and objectiveInflammation is an important factor in the development of aneurysm, and has been identified as a key characteristic predictive of rupture of intracranial aneurysm (IA). However, the role of inflammatory peripheral blood cell ratios in patients with IA has not been well delineated.MethodsA total of 1,209 patients, including 1,001 with unruptured IA and 208 with ruptured IA, were enrolled in this study. Neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), platelet-to-neutrophil ratio (PNR), and platelet-to-white-blood-cell ratio (PWR) were compared between ruptured and unruptured IA.ResultsCompared with the ruptured IA group, the unruptured IA group had higher PNR {median, 65.96 [interquartile range (IQR) 48.95–85.05] vs. 37.78 (IQR, 23.17–54.05); p &lt; 0.001} and PWR [median, 36.89 (IQR 29.38–44.56) vs. 22.39 (IQR, 16.72–29.29); p &lt; 0.001]. In multivariate analysis, PNR and PWR were independently associated with ruptured IA (p = 0.001 and p &lt; 0.001, respectively). Unruptured IA subgroup analyses according to the PHASES scores showed that a higher PHASES score was associated with significantly higher NLR and erythrocyte sedimentation rate (p &lt; 0.001 and p = 0.025) and lower PNR and PWR (p &lt; 0.001 and p = 0.007).ConclusionsWe demonstrated that lower PNR and PWR levels are associated with ruptured IA and a higher PHASES score. Unlike many other inflammatory markers and bioassays, peripheral blood cell ratios are inexpensive and readily available biomarkers that may be useful for risk stratification in patients with cerebral aneurysm. However, a long-term prospective study is needed to clarify this matter.
Identification of candidate genes associated with clinical onset of Alzheimer’s disease
Authors: Liao Wang , Luo Haoyu , Ruan Yuting , Mai Yingren , Liu Chongxu , Chen Jiawei , Yang Shaoqing , Xuan Aiguo , Liu Jun 
Published: December 2022

Background and objectiveAlzheimer’s disease (AD) is the most common type of dementia, with its pathology like beta-amyloid and phosphorylated tau beginning several years before the clinical onset. The aim is to identify genetic risk factors associated with the onset of AD.MethodsWe collected three microarray data of post-mortem brains of AD patients and the healthy from the GEO database and screened differentially expressed genes between AD and healthy control. GO/KEGG analysis was applied to identify AD-related pathways. Then we distinguished differential expressed genes between symptomatic and asymptomatic AD. Feature importance with logistic regression analysis is adopted to identify the most critical genes with symptomatic AD.ResultsData was collected from three datasets, including 184 AD patients and 132 healthy controls. We found 66 genes to be differently expressed between AD and the control. The pathway enriched in the process of exocytosis, synapse, and metabolism and identified 19 candidate genes, four of which (VSNL1, RTN1, FGF12, and ENC1) are vital.ConclusionVSNL1, RTN1, FGF12, and ENC1 may be the essential genes that progress asymptomatic AD to symptomatic AD. Moreover, they may serve as genetic risk factors to identify high-risk individuals showing an earlier onset of AD.
Effects of psychological interventions on high sports performance: A systematic review
Authors: Reyes-Bossio Mario , Corcuera-Bustamante Santiago , Veliz-Salinas Giancarlo , Villas Boas Junior Marcelo , Delgado-Campusano Mariel , Brocca-Alvarado Paul , Caycho-Rodríguez Tomás , Casas-Apayco Leslie , Tutte-Vallarino Veronica , Carbajal-León Carlos , Brandão Regina 
Published: December 2022

IntroductionIntervention programs in sports psychology aid to modify the thoughts and behaviors of athletes in order to improve their performance in sports settings. For high-performance athletes, these interventions are very relevant, given that they constantly face pressure towards obtaining sporting achievements.MethodsThis systematic review aims to analyze the scientific articles between 2010 and 2020 that evaluated the effect of psychological interventions on high-performance athletes. In the search procedure, nine studies were selected, the most studied variables were psychological skills, psychological flexibility, and stress.ResultsThe 44% of the interventions were designed by the research authors themselves, while the remaining 56% were replicated programs, which already had scientific evidence.DiscussionPsychological interventions have a positive impact on sports performance. This review allows sports institutions and professionals to have more knowledge and resources at their disposal to implement these types of programs in their sports planning.
Quality of life in Vietnamese young adults: A validation analysis of the World Health Organization’s quality of life (WHOQOL-BREF) instrument
Authors: Vu Linh Gia , Nguyen Long Hoang , Nguyen Cuong Tat , Vu Giang Thu , Latkin Carl A. , Ho Roger C. M. , Ho Cyrus S. H. 
Published: December 2022

BackgroundThe abbreviated version of the World Health Organization’s Quality of Life (WHOQOL-BREF) instrument has been widely used to assess the quality of life (QOL) of different population groups.AimsThis study aimed to examine the validity and reliability of the Vietnamese version of WHOQOL-BREF in evaluating the QOL of Vietnamese young adults.MethodsThe WHOQOL-BREF was validated in an online cross-sectional study among 445 young adults from 16 to 35 years in Vietnam. The exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were performed to examine the factorial structure of the instrument. The reliability and validity of the new factorial model were evaluated.ResultsThe EFA and CFA suggested the 3-factor model had better fit models than the theoretical 4-factor model. The internal consistency of factor 1 “External life” and factor 2 “Internal life” were excellent (0.931) and good (0.864), respectively, while the internal consistency of factor 3 “Physical and mental health” was nearly acceptable (0.690). Results indicated that the 3-factor model had good convergent and divergent validity as well as moderate discriminant validity. Scores of factors “External life” and “Internal life” had significant predictive effects on general QOL, general health, and overall QOL (p&lt; 0.05). Meanwhile, factor 3 “Physical and mental health” could only predict general health and overall QOL (p&lt; 0.05).ConclusionThis validation study improves understanding of the characteristics of QOL among young adults in Vietnam. While the theoretical model of WHO can be utilized for global comparisons, a new local model should be considered and cross-culturally adapted to successfully capture the progress of public health interventions for promoting young adults’ QOL.
Core self-evaluation and subjective wellbeing: A moderated mediation model
Authors: Chen Wei , Yang Tao , Luo Jing 
Published: December 2022

ObjectivesMuch has been written documenting the positive association between core self-evaluation and adolescents' subjective wellbeing, but little is known about the mediating and moderating mechanisms which underlay this relationship. This study constructed a moderated mediation model to examine whether meaning in life mediated the relationship between core self-evaluation and subjective wellbeing, and whether this mediating process was moderated by adolescents' self-esteem.MethodsA sample of 1,185 adolescents (11–17 years of age, 51.3% females) completed the Core Self-Evaluation Scale (CSES), the Meaning in Life Questionnaire (MLQ), the Rosenberg Self-esteem Scale (RSES), and the Index of Wellbeing Scale (IWS).ResultsThe results indicate that after controlling for gender and age, core self-evaluation contributed significantly to subjective wellbeing (β = 0.900, p &lt; 0.001). Meaning in life played a mediating role in the relationship between core self-evaluation and subjective wellbeing (β = 0.143, p &lt; 0.01), with core self-evaluation indirectly affecting subjective wellbeing through meaning in life (βindirect = 0.068, 95% CI = [0.024, 0.119]). Self-esteem moderated the path mediated by meaning in life, more specifically, the conditional indirect effect between core self-evaluation and wellbeing was significant for adolescents with medium and low self-esteem (effect = 0.056, 95% CI = [0.014, 0.106]; effect = 0.092, 95% CI = [0.034, 0.159]. Both mediating and moderating effects were shown to exist in the association between core self-evaluation and adolescents' subjective wellbeing.DiscussionBased on the results, the following suggestions can be made: subjective wellbeing can be promoted through interventions such as enhancing adolescents' core self-evaluation and helping them understand the meaning in life, and that greater attention needs to be paid to adolescents with low self-esteem. The findings of this study helpful to clarify the mediation and moderating mechanism of the beneficial influence of adolescents' core self-evaluation on subjective wellbeing.
Comparison of endoscopic thyroidectomy by complete areola approach and conventional open surgery in the treatment of differentiated thyroid carcinoma: A retrospective study and meta-analysis
Authors: Yuan Yuquan , Sun Chenyu , Yin Tingjie , Shao Cong , Pan Bin , Lu Dengwei , Hou Shaodong , Lowe Scott , Bentley Rachel , Chen Shuya , Huang Christy , Cheng Ce , Li Yaru , King Bethany , Zhou Qin , Yan Cunye , Zhang Fan 
Published: December 2022

BackgroundThe feasibility of endoscopic thyroidectomy by complete areola approach (ETCA) remains controversial. This study was conducted by combining our clinical data with the data obtained from a systematic review literature search to examine the effectiveness and safety of ETCA compared with conventional open thyroidectomy (COT) in differentiated thyroid carcinoma (DTC).MethodsA total of 136 patients with a diagnosis of DTC who underwent unilateral thyroidectomy with central neck dissection from August 2020 to June 2021 were enrolled. The enrolled patients were divided into the ETCA group (n = 73) and the COT group (n = 63). The operative time, intraoperative bleeding volume, number of removed lymph nodes, number of metastatic lymph nodes, postoperative drainage volume, length of postoperative hospital stay, postoperative parathyroid hormone (PTH) levels, and complications were analyzed. Then, a systemic review and comprehensive literature search were conducted by using PubMed, Google Scholar, Embase, Web of Science, CNKI, Wanfang, and VIP database up to June 2022. Review Manager software version 5.3 was used for the meta-analysis.ResultsThe results of clinical data showed that there were significant differences between the two groups in the operative time, intraoperative bleeding volume, removed lymph nodes, and postoperative drainage volume. There were no statistical differences in the length of postoperative hospital stay, number of metastatic lymph nodes, postoperative PTH level, and complications. In the systematic review and meta-analysis, 2,153 patients from fourteen studies (including our data) were ultimately included. The results of the meta-analysis found that ETCA had a longer operative time, larger postoperative drainage volume, and lower intraoperative bleeding volume. In terms of the length of postoperative hospital stay, the number of removed lymph nodes, and surgical complications, there was no significant difference between the two groups.ConclusionETCA poses lower surgical bleeding and better cosmetic appearance compared with COT, while the length of operation and postoperative drainage in ETCA is less favorable compared with COT. In addition, ETCA is not inferior to COT in terms of the postoperative hospitalization stay, the number of removed lymph nodes, and surgical complications. Given its overall advantages and risks, ETCA is an effective and safe alternative for patients with cosmetic concerns.
Calcium Enhances Thallium Uptake in Green Cabbage (Brassica oleracea var. capitata L.)
Authors: Jia Yanlong , Xiao Tangfu , Sun Jialong , Ning Zengping , Xiao Enzong , Lan Xiaolong , Chen Yuxiao 
Published: December 2022

Thallium (Tl) is a nonessential and toxic trace metal that is detrimental to plants, but it can be highly up-taken in green cabbage (Brassica oleracea L. var. capitata L.). It has been proven that there is a significant positive correlation between Tl and Calcium (Ca) contents in plants. However, whether Ca presents a similar role for alleviating Tl toxicity in plants remains unclear, and little is known in terms of evidence for both Ca-enhanced uptake of Tl from soils to green cabbage and associated geochemical processes. In this study, we investigated the influence of Ca in soils on Tl uptake in green cabbage and the associated geochemical process. The pot experiments were conducted in 12 mg/kg Tl(I) and 8 mg/kg Tl(III) treatments with various Ca dosages. The results showed that Ca in soils could significantly enhance Tl uptake in green cabbage, increasing 210% in content over the control group. The soluble concentrations of Tl were largely increased by 210% and 150%, respectively, in 3.0 g/kg Ca treatment, compared with the corresponding treatment without Ca addition. This was attributed to the geochemical process in which the enhanced soluble Ca probably replaces Tl held on the soil particles, releasing more soluble Tl into the soil solution. More interestingly, the bioconcentration factor of the leaves and whole plant for the 2.0, 2.5, 3.0 g/kg Ca dosage group were greatly higher than for the non-Ca treatment, which could reach 207%, implying the addition of Ca can improve the ability of green cabbage to transfer Tl from the stems to the leaves. Furthermore, the pH values dropped with the increasing Ca concentration treatment, and the lower pH in soils also increased Tl mobilization, which resulted in Tl accumulation in green cabbage. Therefore, this work not only informs the improvement of agricultural safety management practices for the farming of crops in Tl-polluted and high-Ca-content areas, but also provides technical support for the exploitation of Ca-assisted phytoextraction technology.
Our colonoscopic polypectomy experience in the tertiary hospital endoscopy unit
Authors: CAPOGLU Recayi , GÖNÜLLÜ Emre , BAYHAN Zulfu , AKA Bahaeddin Umur , SABUNCU Emre , YİĞİT Merve , SENTURK Adem 
Published: December 2022

Objective: The aim of this study is to present our experience with colon polyps detected during colonoscopy in our endoscopy unit.
Methods: The files of patients who underwent colonoscopy and at least one polyp detected with colonoscopy in our endoscopy unit between March 2016 and March 2018 were reviewed retrospectively.
Results: We included 428 patients in the study. While 96 (22.4%) polyps were located in more than one colon segment,102 (23.8%) polyps were located in the rectum, 108 (25.2%) in the sigmoid colon, 33 (7.7%) in the descending colon, 41 (9.6%) in the splenic flexure, 25 (5.8%) in the transverse colon, 2 (0.5%) in the hepatic flexure, 33 (7.7%) were in the ascending colon, 20 (4.7%) were in the cecum.
Conclusion:
The compatibility of our polypectomy results with the literature can be considered as an indicator of the quality of colonoscopic examinations performed in our clinic.
Osteogênese associada a terapia celular com finalidade na implantodontia: uma revisão de literatura
Authors: De Oliveira Izabela Daphine Mota , Ferreira Tereza Cecília Rodrigues , Mendonça Lucas Francisco Arruda , De Almeida Liliane , Meira Gabriela de Figueiredo , De Sá Juliana Lopes 
Published: December 2022

Introdução: A área da medicina que utiliza de células para realização de procedimentos terapêuticos de correção estrutural no organismo é a terapia celular. Objetivo: investigar as aplicações da terapia celular na implantodontia. Metodologia: Realizou-se uma revisão integrativa de literatura de acordo com as Diretrizes da Declaração PRISMA. As buscas dos artigos se indexaram na base de dados da PUBMED utilizando os descritores “terapia celular”, “implantodontia” e “osteogênese” obtendo 319 artigos. Resultados: inclui-se no estudo 26 artigos no idioma inglês, o país que mais desenvolveu pesquisa sobre a temática estudada foi a China com (27%) e o ano com maior número de estudos selecionado foi o de 2019 com oito artigos (30%). Conclusão: destaca-se que houve uma grande quantidade de desenhos in vitro selecionados nessa revisão integrativa, estudos esses que são ditos como a base da pirâmide da evidência científica, o que reforça a ideia de que estamos no início dos desdobramentos e aplicações dessa terapia na implantodontia sendo necessário o desenvolvimento constate de mais estudos sobre a temática.
الرؤية القانونية لمعاملات المؤسسات المالية دولياً
Authors: المياحي عمار فوزي , احمد ليلى فوزي 
Published: December 2022

أنّ تزايد القيود المفروضة على البنوك الأجنبية العاملة في البلدان النامية منذ الأزمة المالية العالمية 2009/2007 يعرقل تحسين آفاق النمو من خلال الحد من تدفق الموارد التمويلية التي تشتد إليها حاجة الشركات والقطاع العائلي.
ويمكن أن تكون للبنوك العالمية منافع هامة للتنمية، ولكنها ليست دواء شافيا، كما تحمل مخاطر. ويحسن صانعو السياسات بالبلدان النامية الصنع ببحث كيفية تحقيق أقصى قدر من المنافع من الخدمات المصرفية عبر الحدود مع خفض تكاليفها إلى الحد الأدنى، ودفعت أزمة 2007-2009 وما أعقبها من تراجع في النشاط الاقتصادي إلى إعادة تقييم واسعة النطاق لمنافع وتكاليف الخدمات المصرفية الدولية وأدت إلى فرض قيود عطّلت ما تحقق في عشر سنوات من عولمة الخدمات المالية والإقراض عبر الحدود. بيد أن البلدان النامية قد تحتاج إلى إعادة النظر في قيمة البنوك العالمية باعتبارها بوابات هامة للائتمان العالمي وتسريع وتيرة النمو الاقتصادي حتى مع استمرارها في إدارة المخاطر.
ومع استمرار تزايد الطموحات في جميع أنحاء العالم، وتطور القطاع المصرفي، هناك سؤال حاسم: هل سيكون التمويل صديقا أم عدوا في الكفاح من أجل إنهاء الفقر؟.. تخلق البنوك العالمية مخاطر تصدير عدم الاستقرار، لا سيما للبلدان ذات الأنظمة والمؤسسات الضعيفة، ويتعين التخفيف من حدة هذه المخاطر. لكن بدون قطاع مصرفي تنافسي، لن يتمكن الفقراء من الحصول على الخدمات المالية الأساسية، وسيخرج العديد من الشركات من السوق، وسيتوقف النمو في البلدان النامية ".
إن التمويل المصرفي ضروري لقطاع خاص نشيط، لا سيما من أجل رعاية الشركات الصغيرة والمتوسطة. ويمكن للبلدان النامية أن تحقق أقصى قدر من المنافع من نظام مصرفي أقوى مع توفير الحماية من المخاطر من خلال تحسين تبادل المعلومات عبر سجلات الائتمان، وإعمال حقوق الملكية والعقود بقوة، وضمان الإشراف القوي على البنوك .
ومع تراجع بنوك البلدان المتقدمة بعد الأزمة، ملأت بنوك البلدان النامية الفراغ وتوسعت عبر الحدود، وهي تمثل 60% من القيود المصرفية الجديدة منذ الانكماش. وكانت النتيجة زيادة في العلاقات المصرفية بين البلدان النامية وإضفاء الطابع الإقليمي على العمليات المصرفية الدولية().
MERAWAT TRADISI MEMPERTAHANKAN EKSISTENSI: STUDI ETNOBOTANI TANAMAN OBAT SUKU OSING KABUPATEN BANYUWANGI
Authors: Febrianto Hendra 
Published: December 2022

Setiap daerah di Indonesia pasti memiliki kearifan lokal tersendiri yang khas dan tentu tidak dimiliki oleh daerah lain. Terdapat berbagai macam bentuk dan kearifan lokal yang tertuang baik dalam nilai nilai keseharian, sastra, tutur dan hukum adat serta dalam bentuk upacara adat maupun kepercayaan. Upacara adat yang dilakukan oleh suku asli Banyuwangi, suku osing pada setiap ritual keaagamaan yang dilakukan disetiap daerahnya memiliki ritual dan tujuan yang berbeda. Upacara adat yang dilakukan oleh suku osing tidak lepas dari pengaruh dan kepercayaan akan unsur mistis yang diyakini dan terwarisi secara turun temurun. Upacara ini biasanya melibatkan penggunakan tanaman tertentu, yang juga mengandung manfaat sebagai obat oleh masyarakat lokal. Oleh kerena itu perlu adanya penelitian secara mendalam mengenai mempertahankan eksistensi tanaman obat suku osing dalam kerangka etnobotani dan makna folosofisnya yang kemudian didokumentasikan dalam bentuk sebuah budaya.
SOCIAL THEORY AT WORK
Authors: Marcelo Zunino Hugo 
Published: December 2022

While many geographers have focused on the structural conditions inftuencing the reconfiguration of urban areas in Latin America, the concrete ways in which actors attempt to advance particularistic interests and the relations of cooperation, cooptation, and resistance generated among actors remain largely ignored. This gap in the urban literature can be explained by the lack of an analytical framework to study how power is executed in particular social contexts. Based on theoretical elements derived from the work of Anthony Giddens and Michel Foucault, | suggest and apply a framework to disentangle power relations at work in the redevelopment of Concepción's riverfront.