bluuebunny/crossref_metadata_2025_split huggingface dataset:
Incidence and factors influencing neck shortening after screw fixation of femoral neck fractures with the femoral neck system
Authors: Wang Kai , Lin Dongze , Chen Peisheng , Lin Chaohui , Feng Tianxuan , Liu Jiajie , Zheng Shunze , Liang Yaqian , Ouyang Jirui , Cui Yubo , Lin Fengfei 
Published: April 2023

AbstractObjectiveTo investigate the effects of postoperative femoral neck shortening in patients with femoral neck fractures fixed with femoral neck system screws (FNS) and to explore the factors influencing femoral neck shortening.MethodTo retrospectively analyze the data of 113 patients with femoral neck fractures admitted to the Second Hospital of Fuzhou City, affiliated with Xiamen University, between December 2019 and January 2022. Of these, 87 patients were followed up for more than 12 months, 49 men and 38 women: 36 cases of Garden I and II fractures and 51 cases of Garden III and IV fractures, to record the patient's hip Harris score at 12 months postoperatively. Patients were divided into femoral neck shortening group and femoral neck no shortening group according to their regular postoperative follow-up radiographic measurements. To count the incidence of femoral neck shortening, a comparison of postoperative complication rates and hip Harris scores between the two groups was made. Statistical comparison of the two groups and a multifactorial logistic regression analysis were also performed to analyze the factors affecting femoral neck shortening.ResultsAll 87 patients were followed up for more than 12 months after surgery. In 34 of these cases, neck shortening occurred, and the incidence rate was 39.1%. 15 cases of severe shortening, incidence of 17.2%; fracture healing 84 cases, fracture healing rate of 96.5%. The hip Harris score was 83.99 (81.95, 89.20) in the neck shortening group at 12 months postoperatively, 90.87 (87.95, 94.80) for the group without neck shortening; the difference between the two groups was statistically significant (P < 0.01). 32 cases of fracture healing in the neck shortening group at 12 months after surgery, fracture healing rate of 94.1%; 52 cases healed without neck shortening group, fracture healing rate of 98.1%. The difference between the two groups was not statistically significant (P = 0.337). High incidence of neck shortening after FNS fixation of femoral neck fractures, cortical comminution of the severed end, fracture fractionation and quality of reduction were significantly correlated with neck shortening.ConclusionHigh incidence of postoperative neck shortening after internal fixation of femoral neck fractures with the femoral neck system, the cortical comminution, the type of fracture, and the quality of fracture reduction are the influencing factors; femoral neck shortening can affect postoperative hip function, but does not affect fracture healing.
Comparison of modified U-shaped and inverted L-shaped medial capsulorrhaphy in hallux valgus surgery: a prospective, randomized controlled trial of 75 patients
Authors: Wei Xiaohua , Liu Xiong , Zhang Peng , Liu Shifeng 
Published: April 2023

Abstract
Purpose
The purpose of this study was to report a modified U-shaped medial capsulorrhaphy and compare its clinical and radiological differences with an inverted L-shaped capsulorrhaphy in hallux valgus (HV) surgery.

Methods
A prospective study of 78 patients was performed between January 2018 and October 2021. All patients underwent chevron osteotomy and soft tissue procedures for HV, and the patients were randomly separated into 2 groups according to the medial capsule closing techniques: a modified U-shaped capsulorrhaphy (group U) and an L-shaped capsulorrhaphy (group L). All patients were followed for at least a year. The preoperative and follow-up data were collected for each patient and included patient demographics, weight-bearing radiographs of the foot, the active range of motion (ROM) of the first metatarsophalangeal (MTP) joint and the American Orthopedic Foot and Ankle Society (AOFAS) forefoot score. Mann–Whitney U test was used for the comparison of the postoperative measures between the groups.

Results
In total, 75 patients with 80 affected feet met the inclusion criteria, with 38 patients (41 feet) in group U and 37 patients (39 feet) in group L. One year after surgery, the mean hallux valgus angle (HVA), intermetatarsal angle (IMA), and AOFAS score in group U improved from 29.5 to 7.1, from 13.4 to 7.1, and from 53.4 to 85.5, respectively. The mean HVA, IMA, and AOFAS score in group L improved from 31.2 to 9.6, from 13.5 to 7.9, and from 52.3 to 86.6, respectively. Comparing the 1-year postoperative measures between the 2 groups, a significant difference was found in HVA (P = 0.02), but not found in IMA and AOFAS score (P = 0.25 and P = 0.24, respectively). The mean ROM of the first MTP joint was 66.3 degrees preoperatively and 53.3 degrees at the 1-year follow-up in group U, while 63.3 and 47.5 in group L. The degrees of ROM after 1 year in group U were better than those in group L (P = 0.04).

Conclusion
Compared to the inverted L-shaped capsulorrhaphy, the modified U-shaped capsulorrhaphy provided a better ROM of the first MTP joint; at 1 year following surgery, the modified U-shaped capsulorrhaphy maintained the normal HVA better.
Report of natural Mayaro virus infection in Mansonia humeralis (Dyar & Knab, Diptera: Culicidae)
Authors: De Sousa Flávia Barreto , de Curcio Juliana Santana , do Carmo Silva Lívia , da Silva Diego Michel Fernandes , Salem-Izacc Silvia Maria , Anunciação Carlos Eduardo , Ribeiro Bergmann Morais , Garcia-Zapata Marco Tulio A. , de Paula Silveira-Lacerda Elisângela 
Published: April 2023

Abstract
Background
Arboviruses are a group of viruses transmitted to vertebrate hosts by certain blood-feeding arthropods. Among urban vectors of arboviruses, mosquitoes of the genus Aedes are the most common. However, other mosquitoes may be susceptible to infection and involved in the transmission, such as Mansonia spp. Therefore, this study aimed to investigate whether Mansonia humeralis can be infected with the Mayaro virus (MAYV).

Methods
These insects were collected from 2018 to 2020 in chicken coops of rural communities in Jaci Paraná in Porto Velho, Rondônia, Brazil, while performing blood-feeding on roosters. The mosquitoes were randomly grouped in pools from which the head and thorax were macerated and checked for the presence of MAYV by quantitative reverse transcription polymerase chain reaction (RT-qPCR). The positive pools were used to infect the C6/36 cell line, and on different days post-infection, the supernatant of the infected cells was subjected to viral detection by RT-qPCR.

Results
A total of 183 pools of female mosquitoes were tested, of which 18% were positive for MAYV; some samples from insect pools inoculated into C6/36 cells showed in vitro multiplication capacity between 3 and 7 days post-infection.

Conclusions
This is the first report of Ma. humeralis mosquitoes that are naturally infected by MAYV, indicating that these vectors may be potential transmitting agents of this arbovirus.

Graphical Abstract
Analysis of antibiotic resistance gene cassettes in a newly identified Salmonella enterica serovar Gallinarum strain in Korea
Authors: Tran Thanh Quang , Park Minyoung , Lee Jong Eun , Kim Soo Hyun , Jeong Jae-Ho , Choy Hyon E. 
Published: April 2023

AbstractAntimicrobial resistant pathogens are a global health threat driven by the indiscriminate use of antimicrobials. Antimicrobial resistance can be acquired by resistance genes encoded by mobile genetic elements. In this study, we identified a strain of Salmonella enterica serovar Gallinarum (SG4021) from an infected chicken in Korea and characterized the presence of resistance genes in its plasmid by whole genome sequencing. The sequence was then compared with that of a plasmid (P2) from strain SG_07Q015, the only other strain of S. Gallinarum isolated in Korea for which a genome sequence is available. The results revealed that both strains harbored nearly identical DNA carrying antibiotic resistance gene cassettes inserted into integron In2 of the transposable element Tn21, namely an aadA1 resistance gene conferring resistance to aminoglycosides and a sul1 resistance gene conferring resistance to sulfonamide. Interestingly, despite the presence of sul1 in SG4021, an antibiotic sensitivity test revealed that it was sensitive to sulfonamides. Further analysis revealed that this disparity was due to the insertion of a ~ 5 kb ISCR16 sequence downstream of the promoter driving sul1 expression in SG4021. Using various mutants, we showed that the insertion of ISCR16 blocked the expression of the sul1 gene from the upstream promoter. Therefore, the functionality of antimicrobial resistance genes determines phenotypic antimicrobial resistance.
On a reverse Hardy–Hilbert-type integral inequality involving derivative functions of higher order
Authors: Huang Xingshou , Yang Bicheng , Huang Chunmiao 
Published: April 2023

AbstractBy means of the weight functions, the idea of introducing parameters and the technique of real analysis related to the beta and gamma functions, a new reverse Hardy–Hilbert-type integral inequality with the homogeneous kernel as $\frac{1}{(x + y)^{\lambda + m + n}}$

1

(
x
+
y
)

λ
+
m
+
n

($\lambda > 0$
λ
>
0
) involving two derivative functions of higher order is given. As applications, the equivalent statements of the best possible constant factor related to several parameters are considered, and some particular inequalities are obtained.
Conformable fractional versions of Hermite–Hadamard-type inequalities for twice-differentiable functions
Authors: Hezenci Fatih , Kara Hasan , Budak Hüseyin 
Published: April 2023

AbstractIn this paper, new inequalities for the left and right sides of the Hermite–Hadamard inequality are acquired for twice-differentiable mappings. Conformable fractional integrals are used to derive these inequalities. Furthermore, we provide our results by using special cases of obtained theorems.
Criminal law regulation of cyber fraud crimes—from the perspective of citizens’ personal information protection in the era of edge computing
Authors: Zhang Yu , Dong Haoyun 
Published: April 2023

AbstractCurrently, cloud computing provides users all over the globe with Information and Communication Technology facilities that are utility-oriented. This technology is trying to drive the development of data center design by designing and building them as networks of cloud machines, enabling users to access and run the application from any part of the globe. Cloud computing provides considerable benefits to organizations by providing rapid and adaptable ICT software and hardware systems, allowing them to concentrate on creating innovative business values for the facilities they provide. The right to privacy of big data has acquired new definitions with the continued advancement of cloud computing, and the techniques available to protect citizens’ personal information under administrative law have managed to grow in a multitude. Because of the foregoing, internet fraud is a new type of crime that has emerged over time and is based on network technology. This paper analyzed and studied China’s internet fraud governance capabilities, and made a comprehensive evaluation of them using cloud computing technology and the Analytic Hierarchy Process (AHP). This paper discussed personal information security and the improvement of criminal responsibility from the perspective of citizens’ information security and designed and analyzed cases. In addition, this paper also analyzed and studied the ability of network fraud governance in the era of cloud computing. It also carried out a comprehensive evaluation and used the fuzzy comprehensive evaluation method to carry out the evaluation. A questionnaire survey was used to survey 100 residents in district X of city Z and district Y of the suburban area. Among the 100 people, almost all of them received scam calls or text messages, accounting for 99%, of which 8 were scammed. Among the people, more than 59.00% of the people expressed dissatisfaction with the government’s Internet fraud satisfaction survey. Therefore, in the process of combating Internet fraud, the government still needs to step up its efforts.
System, institutional, and client-level factors associated with formal healthcare utilisation among older adults with low income under a social protection scheme in Ghana
Authors: Agyemang-Duah Williams , Asante Dennis , Oduro Appiah Joseph , Morgan Anthony Kwame , Mensah Isaac Verberk , Peprah Prince , Mensah Anthony Acquah 
Published: April 2023

Abstract
Background
In sub-Saharan African context, effect of system, institutional and client-level factors on formal healthcare utilisation among older adults with low income, especially those under a social protection scheme (called Livelihood Empowerment against Poverty [LEAP] programme) is least explored in the literature. However, an adequate understanding of how these factors contribute to formal healthcare utilisation among older adults who are classified as poor (in terms of low income) is important to inform health policy decisions. The aim of this study, therefore, was to examine the contributions of system, institutional and client-level factors in formal healthcare utilisation among older adults with low income under the LEAP programme in Ghana.

Methods
Data associated with this study were obtained from an Ageing, Health, Lifestyle and Health Services survey conducted between 1 and 20 June 2018 (N = 200) in the Atwima Nwabiagya Municipal and Atwima Nwabiagya North District of Ghana. Multivariable logistic regressions were used to determine system, institutional and client-level factors associated with formal healthcare utilisation among older adults with low income under the LEAP programme in Ghana. The significance of the test was set at a probability value of 0.05 or below.

Results
The study revealed that participants who relied on the LEAP programme and/or health insurance subscription to cater for their healthcare expenses (AOR: 11.934, CI: 1.151-123.777), those whose family/caregivers decided on when and where to use formal healthcare (AOR:12.409; CI: 2.198–70.076) and those who did not encounter communication problem with healthcare providers (AOR: 1.358; CI: 1.074–3.737) were significantly more likely to utilise formal healthcare services compared with their counterparts. The study further found that participants who perceived the attitude of healthcare providers as poor (AOR: 0.889; CI: 0.24–0.931) and those who spent 20–40 minutes at the healthcare facility were significantly less likely to utilise formal healthcare services compared with their counterparts (AOR: 0.070; CI: 0.006–0.195).

Conclusion
Our findings suggest that reducing waiting time at healthcare facilities, improving social protection and/or health insurance schemes, improving patient-doctor communication and promoting attitudinal change programmes (such as orientations and supportive supervision) for healthcare providers may help to facilitate the use of needed formal healthcare services by older adults with low income in Ghana.
Positive mood-related gut microbiota in a long-term closed environment: a multiomics study based on the “Lunar Palace 365” experiment
Authors: Hao Zikai , Meng Chen , Li Leyuan , Feng Siyuan , Zhu Yinzhen , Yang Jianlou , Han Liangzhe , Sun Leilei , Lv Weifeng , Figeys Daniel , Liu Hong 
Published: April 2023

Abstract
Background
Psychological health risk is one of the most severe and complex risks in manned deep-space exploration and long-term closed environments. Recently, with the in-depth research of the microbiota–gut–brain axis, gut microbiota has been considered a new approach to maintain and improve psychological health. However, the correlation between gut microbiota and psychological changes inside long-term closed environments is still poorly understood. Herein, we used the “Lunar Palace 365” mission, a 1-year-long isolation study in the Lunar Palace 1 (a closed manned Bioregenerative Life Support System facility with excellent performance), to investigate the correlation between gut microbiota and psychological changes, in order to find some new potential psychobiotics to maintain and improve the psychological health of crew members.

Results
We report some altered gut microbiota that were associated with psychological changes in the long-term closed environment. Four potential psychobiotics (Bacteroides uniformis, Roseburia inulinivorans, Eubacterium rectale, and Faecalibacterium prausnitzii) were identified. On the basis of metagenomic, metaproteomic, and metabolomic analyses, the four potential psychobiotics improved mood mainly through three pathways related to nervous system functions: first, by fermenting dietary fibers, they may produce short-chain fatty acids, such as butyric and propionic acids; second, they may regulate amino acid metabolism pathways of aspartic acid, glutamic acid, tryptophan, etc. (e.g., converting glutamic acid to gamma–aminobutyric acid; converting tryptophan to serotonin, kynurenic acid, or tryptamine); and third, they may regulate other pathways, such as taurine and cortisol metabolism. Furthermore, the results of animal experiments confirmed the positive regulatory effect and mechanism of these potential psychobiotics on mood.

Conclusions
These observations reveal that gut microbiota contributed to a robust effect on the maintenance and improvement of mental health in a long-term closed environment. Our findings represent a key step towards a better understanding the role of the gut microbiome in mammalian mental health during space flight and provide a basis for future efforts to develop microbiota-based countermeasures that mitigate risks to crew mental health during future long-term human space expeditions on the moon or Mars. This study also provides an essential reference for future applications of psychobiotics to neuropsychiatric treatments.
Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis
Authors: Yin Jing-Xian , Agbana Yannick Luther , Sun Zhi-Shan , Fei Si-Wei , Zhao Han-Qing , Zhou Xiao-Nong , Chen Jun-Hu , Kassegne Kokouvi 
Published: April 2023

Abstract
Background
Coronavirus disease 2019 (COVID-19) can involve persistence, sequelae, and other clinical complications that last weeks to months to evolve into long COVID-19. Exploratory studies have suggested that interleukin-6 (IL-6) is related to COVID-19; however, the correlation between IL-6 and long COVID-19 is unknown. We designed a systematic review and meta-analysis to assess the relationship between IL-6 levels and long COVID-19.

Methods
Databases were systematically searched for articles with data on long COVID-19 and IL-6 levels published before September 2022. A total of 22 published studies were eligible for inclusion following the PRISMA guidelines. Analysis of data was undertaken by using Cochran's Q test and the Higgins I-squared (I2) statistic for heterogeneity. Random-effect meta-analyses were conducted to pool the IL-6 levels of long COVID-19 patients and to compare the differences in IL-6 levels among the long COVID-19, healthy, non-postacute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (non-PASC), and acute COVID-19 populations. The funnel plot and Egger's test were used to assess potential publication bias. Sensitivity analysis was used to test the stability of the results.

Results
An increase in IL-6 levels was observed after SARS-CoV-2 infection. The pooled estimate of IL-6 revealed a mean value of 20.92 pg/ml (95% CI = 9.30–32.54 pg/ml, I2 = 100%, P < 0.01) for long COVID-19 patients. The forest plot showed high levels of IL-6 for long COVID-19 compared with healthy controls (mean difference = 9.75 pg/ml, 95% CI = 5.75–13.75 pg/ml, I2 = 100%, P < 0.00001) and PASC category (mean difference = 3.32 pg/ml, 95% CI = 0.22–6.42 pg/ml, I2 = 88%, P = 0.04). The symmetry of the funnel plots was not obvious, and Egger’s test showed that there was no significant small study effect in all groups.

Conclusions
This study showed that increased IL-6 correlates with long COVID-19. Such an informative revelation suggests IL-6 as a basic determinant to predict long COVID-19 or at least inform on the “early stage” of long COVID-19.
Using corporate foresight to enhance strategic management practices
Authors: Demneh Mohsen Taheri , Zackery Ali , Nouraei Amir 
Published: April 2023

AbstractThe ever-increasing environmental complexity makes strategizing a difficult multidimensional task. In this paper, we conducted a corporate foresight case study in an SME in packaging industry in Iran. The case study offers a detailed procedure of implementing corporate foresight (CF) and how it can reshape traditional strategic planning. A multimethodological approach was taken in this case study. Once an intraorganizational team in studied company was formed, archival document analysis, PESTEL and weak signal analysis, importance/uncertainty matrix, cross-impact balanced (CIB) analysis, scenario construction, wind tunneling, robust decision-making, and premortem session were used to create foresight intelligence. This paper presents a detailed description of how CF can be linked to conventional strategizing and reshape it. Key variables, driving forces, critical uncertainties, and 4 plausible scenarios are presented. The case study illustrates that as alternative realities challenged the foresight teams ingrained presuppositions, they found the dialectic between “weight of history” and “pull of future” both revelatory and indigestible. The CF intervention illuminated the fragility of preexisting strategic objectives, the implicit optimism bias underlying them, and an overflowing-plate syndrome of formulating too many strategic objectives. Consequently, studied company decided to revisit their strategic objectives, prepare a contingency plan for worst-case scenarios, and begin developing a crisis-ready culture. The comprehensive case study demonstrates how CF can enhance and contradict traditional strategizing, presents a rich know-how of added value of scenarios, and provides some subtleties and complexities of CF interventions.