bluuebunny/crossref_metadata_2025_split huggingface dataset:
To study the effect of three different doses of dexmedetomidine as premedication on the incidence and severity of etomidate-induced myoclonus
Authors: Kaushal Ketki , Kumari Anita , Abbi Pooja , Gupta Ruchi 
Published: May 2023

Background and Aims:
Etomidate, a carboxylated imidazole is a rapid-acting nonbarbiturate, nonopioid hypnotic agent that has unique hemodynamic stability, favorable toxic profile, and rapid recovery after a single dose. Myoclonus may occur when etomidate is used for induction of general anesthesia. We tested the hypothesis that premedication with different doses of dexmedetomidine reduces the incidence and severity of myoclonus as well as the side effects induced by etomidate.

Materials and Methods:
This prospective, randomized, double-blinded study was done on ninety patients undergoing elective surgical procedures who were randomly allocated into three groups for intravenous administration of premedication of 0.3 μg/kg (Group DL), 0.5 μg/kg (Group DM), and 1.0 μg/kg (Group DH) dexmedetomidine in 100 mL normal saline 10 min before induction of general anesthesia with 0.3 mg/kg etomidate. The primary outcome was to evaluate the incidence of etomidate-induced myoclonus, while the severity of etomidate-induced myoclonus and the incidence of adverse effects were taken as secondary outcomes.

Results:
The incidence of etomidate-induced myoclonus was reduced by 13.3% in Group DL, 36.7% in Group DM, and 56.7% in Group DH. The severity of myoclonus was significantly reduced in Group DH as compared to Group DL and DM (P = 0.001). Side effects such as bradycardia, hypotension, and nausea and vomiting were comparable among the three groups.

Conclusion:
Premedication with dexmedetomidine 1 μg/kg before induction of general anesthesia not only resulted in a 56.7% reduction in the incidence of etomidate-induced myoclonus but also reduced the severity of myoclonus, without inducing any significant adverse effects, as compared to other two doses.
Calidad de vida y hábitos saludables en las aulas. Una alternativa para el diagnóstico y monitorización de la diabetes mellitus a través de compuestos volátiles orgánicos (Quality of life and healthy habits in the classroom. An alternative for the diagnosis and monitoring of dia-betes mellitus through volatile organic compounds)
Authors: Ortiz Cermeño Eva , Rabadán Almela María 
Published: May 2023

La Diabetes Mellitus (DM) es un trastorno bioquímico común y generalizado que afecta a casi 400 millones de personas en todo el mundo. Es una enfermedad multiorgánica que produce graves complicaciones que pueden poner en peligro la vida. En situaciones de hipoglucemia, la capacidad de concentración y la intensidad de la actividad física pueden reducirse. Hay que establecer seminarios y actividades pedagógicas en las aulas, con la finalidad de evitar el riesgo entre el estudiantado de desarrollar esta enfermedad, que va en aumento cada vez más entre las personas sedentarias, con sobrepeso y hábitos alimentarios poco saludables. Esta investigación trata de establecer las características y factores a tener en cuenta para identificar un perfil de VOCs (Compuestos Orgánicos Volátiles) presentes en aire exhalado. Se ha llevado a cabo una revisión sistemática en base a la Declaración PRISMA por el método QUADAS-2 (Quality Assessment of Diagnostic Accuracy Studies 2). Se concluye que la principal ventaja de este enfoque muestra un método no invasivo que puede ayudar a mejorar la calidad de vida de las personas. Una estrategia prometedora para llevar a cabo el diagnóstico y seguimiento de esta enfermedad crónica. La práctica del deporte y la actividad física puede favorecer progresos a nivel terapéutico y preventivo obteniendo beneficios óptimos para la salud.
Palabras Clave: Salud, estudiante, calidad de vida, deporte, método de aprendizaje, educación, diagnóstico de enfermedades.
Abstract. Diabetes Mellitus (DM) is a common and widespread biochemical disorder that affects nearly 400 million people worldwide. It is a multiorgan disease that produces serious and lifethreatening complications. In situations of hypoglycaemia, the ability to concentrate and the intensity of physical activity may be reduced. It’s necessary to establish seminars and pedagogical activities in the classrooms, in order to avoid the risk among students of developing this disease, which is increasing more and more among sedentary people, overweight and unhealthy eating habits. This research tries to establish the characteristics and factors to take into account to identify a profile of VOCs (Volatile Organic Compounds) present in exhaled air. A systematic review has been carried out based on the PRISM Declaration by the QUADAS-2 (Quality Assessment of Diagnostic Accuracy Studies 2) method. It’s concluded that the main advantage of this approach shows a non invasive method that can help improve people’s quality of life. The practice of sport and physical activity can promote progress at a therapeutic and preventive level, obtaining optimal health benefits.
Keywords: Health, student, quality of life, sport, learning method, education, diagnosis of diseases.
Improved PCNN Polarization Image Denoising Method Based on Grey Wolf Algorithm and Non-Subsampled Contourlet Transform
Authors: Li Yuhai , Sun Yuxin , Feng Kai 
Published: May 2023

In this article, an adaptive pulse-coupled neural network (PCNN) polarization image denoising method based on Grey Wolf Optimization (GWO) and Non-Subsampled Contourlet Transform(NSCT) is proposed. Different from the traditional PCNN denoising method, the captured polarization image was firstly devised by the NSCT and enforced band-decomposition to denoised by PCNN. The evaluable index of the image was used for quantitative analysis. Then, GWO is used to update PCNN inherent voltage constant and attenuation time constant and neurons connected intensity factor three model parameters, after looking for multiple optimal solutions, and then to polarized image denoising to achieve the best effect. This method not only avoids the image edge blurring caused by the traditional image denoising method, but also solves the problem that the parameters of the PCNN are difficult to accurately estimate. Hence, it is more suitable for polarization images containing noise. The experiment and the quantitative analysis of image evaluation indices showed that NSCT-GWO-PCNN effectively suppresses the noise in polarization image by reducing salt-and-pepper noise while protecting edges.

Received: 7 April 2023 | Revised: 15 May 2023 | Accepted: 19 May 2023

Conflicts of InterestThe authors declare that they have no conflicts of interest to this work.

Data Availability StatementData sharing is not applicable to this article as no new data were created or analyzed in this study.
Arte digital
Authors: Lannes Yuri Nathan da Costa , Chagas Luíza Rodrigues , Soares Marcelo Negri 
Published: May 2023

Os direitos da personalidade se relacionam com o direito do autor, na medida em que é corolário da dignidade humana a transparência nos royalties, dividendos e remuneração contratual, com seu caráter alimentar, sendo que a NFT, com a tecnologia blockchain, garante a segurança da veiculação da arte em meio digital, seja quanto à originalidade autoral, seja com a sequência registral dos direitos e usos. Nesse aspecto, por meio do método hipotético-dedutivo, o presente artigo, com esteio na liberdade de expressão, na arte e também em obras de arte que substituem o pincel e tinta, na música e tantos outros meios digitais, o presente artigo versará sobre o exercício do direito autoral sobre os NFTs de arte digital, observando os dispositivos da Lei nº 9.610/98, conhecida também como a Lei dos Direitos Autorais. Notadamente, demonstra-se a verticalização da investigação, de modo único, típica de trabalhos pós-graduados. O resultado é que, nesses standards e equiparados, sobressai a proteção dos direitos fundamentais e da personalidade, favorecendo a liberdade de expressão, a arte como um todo, beneficiada pelas novas tecnologias, sem prejuízo de apresentar, pontualmente, malefícios ou neutralidades.
A STUDY OF DEMOGRAPHIC PROFILE ASSOCIATION WITH SEROPOSITIVE CASES OF DENGUE VIRUS INFECTION IN LAHORE
Authors: JALEES KHALID KHAN  , QURAT UL AIN  , AMNA SABIR  , RAFEEDA MAAB  , KHADEJA IQBAL  , MUHAMMAD ABDUL-REHMAN  
Published: May 2023

Introduction: Dengue fever is caused by a flavi virus, called dengue virus. Aedes Egypti and Aedes Albopictus transmit this virus. Diagnosis is through direct i.e. virus isolation, genome detection and antigen detection and indirect i.e. serology IgG and IgM detection methods.
Objective: The objective of the study was to study the association of different epidemiological factors with dengue fever in Lahore.
Material and Methods: 300 suspected dengue cases presenting in Emergency, Dengue isolation ward, different wards and OPD’s of Mayo Hospital, Sir Ganga Ram Hospital and Jinnah Hospital Lahore were obtained.
Sampling: Convenience purposive sampling was opted.
Study Design: It was analytical cross sectional. The different demographic and epidemiological factors were noted to see their association with dengue fever.
Results: 90 patients (30% of total) were positive for IgM and 210(70 % of total) were negative for IgM. 108 patients (36% of total)were positive for IgG and 192(64% of total) were negative for IgG . 54 (18%) were positive for IgM and 63 (21%) males were positive for IgG. 36 females (12%) were positive for IgM and 45 (15%) females were positive for IgG. Simultaneous positivity of both IgG and IgM was in 18 male patients (6%) and in 21 female patients (7%). IgM positivity was more in age group 11-20 (9%) and least in age group 71-80. IgG positivity was more in age group 11-20 (12%) and least in age groups 0-11 and 71-80(2% each). Their mean age were 29.14 + 17.03 (SD) years ranging from 9 months to 90 years? Maximum positivity of IgM and IgG both was observed in Northern Lahore i.e. 48 (19 %). Minimum positivity of both IgM and IgG was observed in Eastern Lahore i.e. 3 (3 %) respectively.
Metabolic syndrome: Comparing Performance of Three Different Diagnostic Criteria in Pakistan
Authors: Khan Muhammad Imran Hasan , Usama Azhar  
Published: May 2023

BACKGROUND
Metabolic syndrome was reported prevalence of 33.4% with the WHO, 22.6% with the NCEP-R, and 30.9% with the IDF criteria in urban population. According to literature, NCEP-R and IDF were most consistent in picking metabolic syndrome (MetS) in non insulin dependent diabetic patients.
AIM
This study evaluated three diagnostic criteria of metabolic syndrome with respect to their sensitivity and specificity, comparing the relation of WHO with IDF and NCEP-R, suggesting most suitable criteria for our population.
MATERIAL AND METHOD
It was a descriptive case-control study carried out in the Diabetes, Endocrine and Metabolic Center, Lahore General Hospital, Lahore (DEMC, LGH) between November 2011 to November 2013. Total 3300 subjects were selected and. interviewed for demographics, everyday features (diet, exercise, smoking, alcohol consumption). Laboratory analysis were used to develop biochemical parameters. .Anthropometric measurements were carried out. Data was analysed using SPSS version 23. Chi-square was used for comparison of proportions. Kappa statistic was used to test degree of agreement between them.
RESULTS
The incidence of MetS in type2 diabetic patients according to WHO criteria was highest, followed by IDF and NCEP-R. IDF and NCEP-R had better specificity. Positive Predictive Value (PPV) was high for NCEP-R and Negative Predictive Value (NPV) for IDF. Kappa showed both were in agreement, with IDF criteria better.
CONCLUSION
WHO criteria was most sensitive in picking diagnosis of MetS. IDF was second in sensitivity and NCEP-R was most specific. There is need to improve awareness, in view of the alarming number of patients.
ISOLATION OF CANDIDA SPECIES FROM CLINICAL SPECIMENS WITH THEIR ANTIFUNGAL SUSCEPTIBILITY PATTERN: AN OBSERVATIONAL STUDY FROM PAKISTAN
Authors: Zohaib Ashraf  , Iffat Javed  , Muhammad Saeed Anwar  , Muna Malik  , Amina Asif  , Fareeha Imran  , Sohaila Mushtaq  , Aasma Noveen Ajmal  
Published: May 2023

Objectives:This study aimed to observe the prevalence of Candida infection in hospital-admitted patients and observe their antifungal susceptibility to treat these admitted patients according to their sensitivity,
Methods:This study was conducted on 105 isolates of Candida species obtained from various clinical samples, including urine, cerebrospinal fluid, invasive catheter tips, blood, and tracheal secretions of patients admitted to a Tertiary Care Hospital in Lahore, Pakistan. The patients taking antifungal and outpatient department samples were excluded from this study. Each sample was processed according to standard operating procedures in the microbiology laboratory of Lahore General Hospital, Lahore, Pakistan, affiliated with Post Graduate Medical Institute, Ameer ud din Medical College, Lahore, Pakistan.
Results:The frequency of Candida species is found to be 5.71% in patients admitted to tertiary care. The most common isolated Candida spp. was Candida tropicalis, followed by Candida albicans. A 27.6% Fluconazole resistance was observed in the isolates. There was no Amphotericin resistance in the Candida isolates both by disc diffusion and on minimum inhibitory concentrations MIC method.
Conclusion:Resistance against the antifungal azole group was observed in the current study. More studies on fungal infection should be conducted in the healthcare sector of developing countries to add more information regarding new emerging resistant fungal infections
STAPHYLOCOCCAL CASSETTE CHROMOSOME MEC TYPES IN NASALLY CARRIED METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS ISOLATES OF HEALTHCARE WORKERS IN A TERTIARY CARE HOSPITAL: A CROSS-SECTIONAL STUDY
Authors: Amina Asif  , Iffat Javed  , Sohaila Mushtaq  , Saeed Anwar  
Published: May 2023

Objective: To determine the frequency and SCCmec type of nasally carried MRSA in HCWs of a tertiary care hospital.
Methods: Nasal swabs were collected from three hundred and eighty healthcare workers working in various clinical wards of Lahore General Hospital, Lahore. The phenotypic resistance to methicillin was determined using Cefoxitin disk 30 µg. All the isolates showing Cefoxitin resistance were confirmed for mecA gene and typed for SCCmec I, II, III, IV (a, b, c, d) and V by PCR. DNA sequencing was done for random isolates for all the SCCmec types recovered in the present study.
Results: Out of 380 nasal samples, 89 (23.42%) cultures yielded the growth of S. aureus out of which 31 (34.83%) were MRSA. The overall frequency of MRSA among all the HCWs was 8.2%. Overall, 47 SCCmec elements were found in total 29 MRSA isolates. Out of 29 MRSA isolates, 13 (44.82%) were hospital acquired, 7 (24.13%) were community acquired and 9 (31.03%) isolates had SCCmec types of both hospital acquired and community acquired origins.
Conclusion: The colonized healthcare workers are harboring Hospital-acquired MRSA more frequently and can act as being acting as mixing bowls of different SCCmec genes. Our study emphasizes the need for the formulation of regular nasal decolonization policies for effective infection control within our healthcare setups.
Seismic risk scenarios for the residential buildings in the Sabana Centro province in Colombia
Authors: Feliciano Dirsa , Arroyo Orlando , Cabrera Tamara , Contreras Diana , Valcárcel Torres Jairo Andrés , Gómez Zapata Juan Camilo 
Published: May 2023

Abstract. Colombia is in one of the most active seismic zones on
Earth, where the Nazca, Caribbean, and South American plates converge.
Approximately 83 % of the national population lives in intermediate to
high seismic hazard zones, and a significant part of the country's building
inventory dates from before the nation's first seismic design code (1984).
At present, seismic risk scenarios are available for the major cities of the country, but there is still a need to undertake such studies in other
regions. This paper presents a seismic risk scenario for the Sabana
Centro province, an intermediate hazard zone located close to the
country's capital. An exposure model was created combining information from
the Global Earthquake Model (GEM) Foundation, surveys, and the national
census. Fragility and vulnerability curves were assigned to the building
types of the region. A hazard model was developed for the region and
18 earthquake scenarios with a return period of 475 years were
simulated using the OpenQuake (OQ) hazard and risk assessment tool to
estimate damage and economic losses. In addition, a social vulnerability
index (SVI) based on demographic information was used to assess the direct
economic loss in terms of replacement costs. The results show that 10 % of all buildings considered in the region would experience collapse, and 7 % would suffer severe damage. Losses account for 14 % of the total replacement cost of the buildings and represent 21 % of the annual gross domestic product (GDP) of the region.
Echoic Re-Presencing
Authors: Borkowski Alex 
Published: May 2023

This paper considers listening as a method in media archaeology—a cluster of technology-oriented approaches to the past that attend to “dead end” inventions outside teleological narratives of progress. In particular, Wolfgang Ernst’s media-archaeological ear advances a materialist approach which favors listening to “the technical signifier rather than […] the acoustic or musical signified.” However, this perspective is subject to recurrent critiques from feminist scholars who highlight the lack of regard for the asymmetrical power structures that undergird technical objects and their exclusion from historical narratives. As a case study, and interrogation of the possibilities for a feminist media archaeology, this paper examines the work of Daphne Oram, a British composer whose contributions to electronic music have been routinely overlooked, and the excavation of her work in Oramics: Atlantis Anew (2011), a film by Aura Satz. The archival vestiges of Oram’s composition technique, in which visual notations on celluloid are sonified by her Oramics Machine, align with, and demand consideration beyond, Ernst’s “ascetic approach to signals.” Through a close reading of Satz’s film, I suggest that her simultaneous attention to the material processes of sound technologies and the erasure of women’s labor posits a necessary extension to this mode of enquiry. Considering recent feminist interventions in media archaeology, as well as critiques in sound studies that drawn on feminist STS to challenge the presumed universality of listening, this paper proposes a framework of media-archaeological listening as echoic re-presencing. Oram’s work, and Satz’s re-prescencing of it, therefore open up possibilities for listening otherwise to the sonic past.
EVALUASI PENYIMPANAN OBAT DI KLINIK PRATAMA LINGKAR BARAT KOTA JAMBI
Authors: Maimum Maimum , Zerlya Ramadika 
Published: May 2023

Pelayanan Kefarmasian adalah suatu pelayanan langsung dan bertanggung jawab kepada pasien yang berkaitan dengan sediaan farmasi dengan maksud mencapai hasil yang pasti untuk meningkatkan mutu kehidupan pasien. Penyimpanan obat dan bahan medis habis pakai merupakan suatu kegiatan pengaturanterhadap obat yang diterima agar aman (tidak hilang), terhindar dari kerusakan fisik maupun kimia dan mutunya tetap terjamin, sesuai dengan persyaratan yang ditetapkan. Tujuannya adalah agar mutu obat yang tersedia di puskesmas dapat dipertahankan sesuai dengan persyaratan yang Berdasarkan surve awal di Klinik Pratama Lingkar Barat. Penyimpanan Obat di Instalasi Farmasi Klinik tersebut memiliki tingkat cakupan 75 %. Maka peneliti ingin melakukan penelitian terhadap Evaluasi Penyimpanan Obat di Klinik Pratama Lingkar Barat. Apakah sistem penyimpanannya sudah sesuai dengan standar penyimpanan yang telah ditetapkan ditetapkan.
Penelitian menggunakan metode penelitian observasional dengan rancangan cross sectional secara deskriptif, dimana penelitian ini bertujuan untuk mengetahui gambaran penyimpanan obat di Klinik Pratama Lingkar Barat Kota Jambi. Penelitian ini dilakukan dengan cara pengumpulan data yaitu data kualitatif dan kuantitatif. Sampel yang diambil adalah data obat yang masuk dalam kategori persentase obat kadaluarsa, persenntase stok mati dan persentase stok akhir menggunakan populasi. Total populasi diambil secara random. Populasi yang digunakan adalah populasi ketersediaan obat di Instalasi Farmasi.
Berdasarkan hasil penelitian dari 20 pertanyaan yang diteliti, penyimpanan obat di Klinik Pratama Lingkar Barat yang sesuai adalah 13 pertanyaan dengan persentase kesesuaian yaitu 65%, dan yang tidak sesuai sebanyak 7 pertanyaan dengan persentase kesesuaian 35 % .Indikator yang belum efisien adalah persentase obat yang kadaluarsa, persentase stok obat mati, dan stok akhir obat.
Moral distress among healthcare professionals during the Covid-19 pandemic: report of an institution-wide survey
Authors: Wanigasekara Assel , Freeborn Julie 
Published: May 2023

BackgroundMoral distress occurs when professionals cannot carry out what they believe to be ethically appropriate actions because of constraints or barriers, possibly exacerbated by Covid-19.MethodsAn exploratory cross-sectional web-based survey was used to distribute the Measurement of Moral Distress for Healthcare Professionals (MMD-HP) at a Covid-19 hospital in the United Arab Emirates.Results238 responses were eligible for analysis. The mean total score of MMD-HP was 79.18 (SD=87.75). Average scores were higher for physicians than nurses, with critical care professionals reporting a significantly higher mean score. The MMD-HP was also associated with intention to leave and employment choices.
Optimization of Closed-loop Supply Chain Network for Vegetable and Fruit Agricultural Products Considering Fuzzy Demand and Purchasing Price
Authors: Fan Zhiqiang , Wang Qinfa 
Published: May 2023

Due to the seasonal and perishable nature of vegetable and fruit agricultural products, which can easily cause sudden changes in demand and prices in a short period of time, a decision model framework was established to address the uncertainty issues related to vegetable and fruit agricultural products. The framework consists of triangular fuzzy numbers, a closed-loop supply chain network model for vegetable and fruit agricultural products, and an optimization model based on chance constrained programming, while considering demand, return rate,utilization rate. And with the goal of minimizing the sum of fixed costs, transportation costs, purchasing costs, packaging costs, storage costs, processing cost and disposal costs in the supply chain network, the model is validated through two scenarios: fuzzy demand and deterministic demand. The model calculation results indicate that under certain other conditions, the return rate is positively correlated with the total cost; The relationship between utilization rate and total cost may be either positive or negative, influenced by the combined effects of transportation costs and disposal costs in reverse logistics activities; The cost increase and facility selection corresponding to adjacent demand proportion nodes are different. Proved the effectiveness and feasibility of the model.