bluuebunny/crossref_metadata_2025_split huggingface dataset:
Acute Myelogenous Leukemia in Pregnancy in a 32yr Old Woman
Authors: Sayibu S.S. , Sefogah P.E. , Coleman J. 
Published: July 2023

Background: Generally a disease of the elderly, Acute Myelogenous Leukemia (AML) very rarely occurs in pregnancy with an estimated incidence of 1 in 75,000 - 100, 000 pregnancies1, 2. There is hardly any data on the difference in its incidence between pregnant women and non-pregnant women in the reproductive age. However, management options are more in the non-pregnant, asthey are in the elderly. Because there is yet no globally agreed standard way of managing this clinical dilemma in pregnancy, various institutions have proposed different management protocols depending on the AML type, degree of symptomatology, gestational age at diagnosis and the patient’s wishes. The objective of this publication is to present our experience with this condition at the Korle Bu Teaching Hospital, to bring attention to the possibility of the condition in our environment as part of differential diagnoses of anaemia or coagulopathy in pregnancy. Case: We report the case of a 32yr old G3P1+1A, at 32weeks 2days gestation diagnosed with and managed for Acute Myeloid Leukemia at the Korle Bu Teaching Hospital, and review of the available literature on this condition in pregnancy.Conclusion: Acute Myelogenous Leukemia is a very rare condition in pregnancy that lacks universally accepted treatment protocols. Management can pose a challenge to clinicians, patients and their relatives. Early accurate diagnosis is difficult in resource-constrainedsettings, and management options are limited when trying to save both fetus and mother. Early accurate diagnosis and prompt referral for appropriate interventions are key in improving outcomes, even in the face of other obstetric complications.
Fendre les images, fendre les choses
Authors: Cannock Alejandro Léon 
Published: July 2023

Partant du fait historico-idéologique qui détermine l’appareil photographique -- sa nature et ses fonctions -- comme un dispositif inventé pour donner à voir ce qui est (« l’actuel »), et donc soumis à la logique de la représentation (« documentaire »), cet article affirme la possibilité, à l’instar de Vilém Flusser, de faire un usage contraire au programme de l’apparatus, c’est-à-dire un usage critique qui nous invite à voir ce qui pourrait être (« le virtuel »). Donc, à penser. Ainsi, en affirmant hypothétiquement l’existence d’un type particulier d’image qualifiée de « pensive », cet article retrace synthétiquement, en soulignant les similitudes et les différences, quelques efforts théoriques (Jacques Rancière, Gilles Deleuze, Roland Barthes, Régis Durand, Georges Didi-Huberman) faits pour cerner cette puissance très singulière des images. Enfin, l’article se demandera si les techniques de compositing (au sens large du terme : collage, patchwork, mosaïque, etc.) constituent un moyen efficace de produire ces images rebelles capables de nous donner à penser et, par conséquent, susceptibles de fendre notre image du monde (critique de l’iconologie) pour fendre le monde (critique de l’idéologie).
Sheila Jeffreys : sens et légitimité d'une critique « totale » de la pornographie aujourd'hui
Authors: Roszak Romain 
Published: July 2023

J'aimerais mettre en relation ici les analyses de la philosophe féministe anglaise Sheila Jeffreys et un certain nombre de discours contemporains francophones sur la pornographie. L'enjeu est multiple. Il s'agit d'abord, bien modestement, de donner à lire Jeffreys dans la mesure où elle n'est pas traduite en français à ce jour. Par là, de donner à voir un féminisme antipornographie vivace, et qui ne se fonde pas sur une vision réductrice de la pornographie, c'est-à-dire sur son catalogue le plus manifestement machiste, hétérocentré, brutal voire sadique. La critique « totale » que mène Sheila Jeffreys, et dont il faudra définir le sens, compliquerait heureusement le débat francophone sur le sort à faire à la pornographie ; il est, en l'état, très incomplet, puisque les seules figures médiatiquement reconnues qui s'opposent à l'enthousiasme queer sur le sujet sont des conservateurs qui tiennent les identités sexuelles pour naturelles et figées ; et puisque la seule opposition, dans le champ intellectuel, qui structure le débat, est celle de la défense de la pornographie en général et de la défense d'une certaine pornographie critique (et d'une manière ou d'une autre « progressiste »). Les analyses de Sheila Jeffreys permettent non seulement de rendre raison du statut et de l'extension de la pornographie aujourd'hui, mais encore de renvoyer les études pornographiques à leur fonction idéologique, sans que cela relève d'un procès d'intention.
Exploring Transnational Dimensions of Activism in Contemporary Book Culture: Ons Klyntji and Afrikaner Activism
Authors: Klingenberg Jana , Miller Samantha 
Published: July 2023

Afrikaans developed in South Africa out of an interaction among a variety of peoples. In the beginning, Afrikaans was considered a language spoken by the lower classes, but it rose from this low position to become an official language in 1925. After the National Party started to govern South Africa in 1948, Afrikaans became the language of the oppressor during apartheid. Post‑apartheid, Afrikaners questioned their identity, feeling conflicted between pride and shame.
The magazine Ons Klyntji was established in 1896 to foster a literary culture and shape Afrikaner identity, and still exists today. Throughout its publication history, the magazine was used to promote progressive causes: first in the creation of an Afrikaans literature, and then as a vehicle for protest by Afrikaners against apartheid. Both these causes developed out of a need to find a distinct identity amongst Afrikaners. The researchers argue that the publishing of Ons Klyntji has contributed positively to progressive political and social change with regards to Afrikaner identity, particularly in the post‑apartheid period.
Awareness and Utilization of Public Physiotherapy Health Care Services to Support People With Multiple Sclerosis: A Health Care Service Audit
Authors: Jasin-Pathiranage Saduni , Grech Lisa B. , Scroggie Charlotte , Sansom Phoebe 
Published: July 2023

ABSTRACT

BACKGROUND:
To maximize functioning and well-being in people with multiple sclerosis (MS), physiotherapy consultation is recommended at the point of diagnosis and throughout the disease course. We wanted to determine whether patients with MS being managed through a large metropolitan hospital in Australia accessed physiotherapy input as part of their MS management consistent with evidence-based recommendations and to identify patients’ self-reported physiotherapy requirements, including symptom management, information needs, and service delivery preferences.

METHODS:
Surveys were sent to 597 MS clinic patients, and 160 responded. Data were analyzed using descriptive methods to derive frequencies and percentages. The survey consisted of 16 questions plus 2 optional questions related to sociodemographics (age and postcode).

RESULTS:
Of 160 respondents, 142 completed all 14 nonoptional questions. One-third of participants (n = 53) were aware of the hospital MS clinic physiotherapy services, with 21.3% (n = 34) saying that they had accessed these services. Conversely, 40.1% of respondents (n = 61) reported having consulted a private physiotherapist. Combined, 52% of respondents reported seeing a physiotherapist. There was a clear preference (94.7%; n = 144) for access to the MS clinic physiotherapy service. The presence of at least 1 current MS-related physiotherapy problem was reported by 82.2 2% of respondents (n = 125). The top ways to access MS-related information were via a specialist MS website (57.6%) and a mobile app (55.6%).

CONCLUSIONS:
There is an unmet need for physiotherapy, and many participants may have foregone services due to unawareness. Improved awareness and uptake of physiotherapy at the point of diagnosis is needed to maximize functioning and well-being in people with MS.
Genome assembly composition of the String “ACGT” array: a review of data structure accuracy and performance challenges
Authors: Magdy Mohamed Abdelaziz Barakat Sherif , Sallehuddin Roselina , Yuhaniz Siti Sophiayati , R. Khairuddin Raja Farhana , Mahmood Yasir 
Published: July 2023

Background
The development of sequencing technology increases the number of genomes being sequenced. However, obtaining a quality genome sequence remains a challenge in genome assembly by assembling a massive number of short strings (reads) with the presence of repetitive sequences (repeats). Computer algorithms for genome assembly construct the entire genome from reads in two approaches. The de novo approach concatenates the reads based on the exact match between their suffix-prefix (overlapping). Reference-guided approach orders the reads based on their offsets in a well-known reference genome (reads alignment). The presence of repeats extends the technical ambiguity, making the algorithm unable to distinguish the reads resulting in misassembly and affecting the assembly approach accuracy. On the other hand, the massive number of reads causes a big assembly performance challenge.

Method
The repeat identification method was introduced for misassembly by prior identification of repetitive sequences, creating a repeat knowledge base to reduce ambiguity during the assembly process, thus enhancing the accuracy of the assembled genome. Also, hybridization between assembly approaches resulted in a lower misassembly degree with the aid of the reference genome. The assembly performance is optimized through data structure indexing and parallelization. This article’s primary aim and contribution are to support the researchers through an extensive review to ease other researchers’ search for genome assembly studies. The study also, highlighted the most recent developments and limitations in genome assembly accuracy and performance optimization.

Results
Our findings show the limitations of the repeat identification methods available, which only allow to detect of specific lengths of the repeat, and may not perform well when various types of repeats are present in a genome. We also found that most of the hybrid assembly approaches, either starting with de novo or reference-guided, have some limitations in handling repetitive sequences as it is more computationally costly and time intensive. Although the hybrid approach was found to outperform individual assembly approaches, optimizing its performance remains a challenge. Also, the usage of parallelization in overlapping and reads alignment for genome assembly is yet to be fully implemented in the hybrid assembly approach.

Conclusion
We suggest combining multiple repeat identification methods to enhance the accuracy of identifying the repeats as an initial step to the hybrid assembly approach and combining genome indexing with parallelization for better optimization of its performance.
Integration of information and communication technologies in management education: a path for success
Authors: Rani Ridhi , Sable Anita , Srinivas Ved , Prasad KDV 
Published: July 2023

We are in VUCA environment, a highly competitive environment, with distributed access to resources. The talented HR can give requisite which could provide the requisite cutting edge services to organizations to flourish. This calls for producing business management graduates who could efficiently handle the next century challenges. To achieve this, revolutionary pedagogical changes have to be made in terms of ICT (Information and Communications Technology) that would come in handy for improving the quality of imparting of management education in general and learning in particular. Many surveys conducted by industry associations like FICCI, CII and Aspiring Minds has pointed out that employability of business management graduates is the major issue. Hence any initiative, such as ICT as a pedagogical change will go a long way in solving this problem apart from enabling the youngsters to contribute to the Gross Domestic product (GDP). This paper aims at examining the role of ICT in improving the quality of management education. It further explores to find whether ICT enabled education enhances the learning experience and provides new skill sets to the students. Design /methodology – This study critically examines the role of ICT in Management education which is based on literature and document review. It has covered educational reports, empirical and theoretical research and various articles. Originality/Value- This is mainly an analytical study by exploring the secondary sources and reviewing documents including the experience of few institutes in the field of management education to make out a case for effective use of ICT.
Consumption Pattern and Competitors’ Analysis of Diced Cheese in Anand and Vadodara Cities of Gujarat, India
Authors: Baruri Sukanya , Vahoniya Dilip R. , Prajapati Mahesh R. , Rajwadi Alvira 
Published: July 2023

Background: The dairy industry is an important sector in the global food industry, offering various essential products like milk, cheese, butter, yogurt, and ice cream. These products are widely consumed for their nutritional benefits, taste, and versatility in cooking. Diced cheese has become a popular culinary ingredient due to its convenience and versatility. It is appreciated for its ease of use and the various ways it can be used in cooking. With pre-cut small pieces, diced cheese eliminates the need for slicing or grating, saving valuable time in the kitchen. Overall, diced cheese is a time-saving and convenient option for home cooks and chefs alike.
Methods: This study aimed to understand consumption patterns for diced cheese in the cities of Anand and Vadodara, Gujarat, India. The research design involved descriptive research using non-probability convenience sampling. Data were collected from 120 consumers through a semi-structured schedule and analyzed using Microsoft Excel and SPSS software.
Findings: The findings revealed that the majority of consumers were male, primarily belonging to the age group of 21-30 years. Nuclear families were the most common family type in both cities. The results also highlighted that a significant percentage of the population was unaware of diced cheese, with social media being the primary source of information. A portion of the respondents had not purchased diced cheese, suggesting a potential growth opportunity for the product in the market. Taste, price, and availability were identified as important factors influencing purchase decisions.
Enhancing Apoptosome Assembly via Mito‐Biomimetic Lipid Nanocarrier for Cancer Therapy
Authors: Han Huijie , Chen Jie , Li Jiachen , Correia Alexandra , Bártolo Raquel , Shahbazi Mohammad‐Ali , Teesalu Tambet , Wang Shiqi , Cui Wenguo , Santos Hélder A. 
Published: July 2023

AbstractApoptosis is the natural programmed cell death process, which is responsible for abnormal cell clearance. However, many cancer cells develop various mechanisms to escape apoptosis through interrupting apoptosome assembly, which is a key step to initiate apoptosis. This promotes tumorigenesis and drug resistance, and thus, poses a great challenge in cancer treatment. Herein, a biomimetic lipid nanocarrier mimicking mitochondrial Cytochrome C (Cyt C) binding is developed. Cardiolipin, the major phospholipid of mitochondrial inner membrane, is introduced as the main component in biomimetic liposomal formulation. With the help of cardiolipin, Cyt C is sufficiently loaded in liposome based on electrostatic and hydrophobic interaction with cardiolipin. Lonidamine (LND) is added in hydrophobic phase of liposome to modulate the metabolic activity within cancer cells and sensitize the cells to Cyt C‐induced apoptosis. The results suggest that LND reduces ATP level and creates favorable environment for Cyt C induced apoptosome assembly, exhibiting higher apoptosis level and anti‐tumor efficacy in vitro and in vivo. The conjugation of a tumor‐homing peptide, LinTT1, on the nanovesicle, increases the efficacy due to enhanced tumor accumulation. Overall, this biomimetic lipid nanocarrier proves to be an efficient delivery system with great potential of pro‐apoptosis cancer therapy.
Tailoring Pressure Sensitive Adhesives with H6XDI‐PEG Diacrylate for Strong Adhesive Strength and Rapid Strain Recovery
Authors: Park Hyunok , Lim Daegyun , Lee Geonwoo , Baek Myung‐Jin , Lee Dong Woog 
Published: July 2023

AbstractThe development of flexible electronic technology has led to convenient devices, including foldable displays, wearable, e‐skin, and medical devices, increasing the need for flexible adhesives that can quickly recover their shape while connecting the components of the device. Conventional pressure sensitive adhesives (PSAs) can improve recoverability via crosslinking, but often have poor adhesive strength. In this study, new types of urethane‐based crosslinkers are synthesized using m‐xylylene diisocyanate (XDI) or 1,3‐bis(isocyanatomethyl)cyclohexane (H6XDI) as a hard segment, and poly(ethylene glycol) (PEG) group as a soft segment. The PSA with the synthesized H6XDI‐PEG diacrylate (HPD) demonstrates a significantly improved recoverability compared to XDI‐PEG diacrylate and a conventional crosslinker 1,6‐hexanediol diacrylate (HDDA) while maintaining high adhesion strength (≈25.5 N 25 mm−1). The excellent recovery property of the PSA crosslinked with HPD is further confirmed by 100k folding tests and 10k multi‐directional stretching tests exhibiting high folding and stretching stability. PSA with HPD also shows high optical transmittance (> 90%) even after 20% straining, suggesting its applicability in fields that simultaneously require high flexibility, recoverability, and optical clarity such as foldable displays.
3D Elastomeric Stent Functionalized with Antioxidative and Perivascular Tissue Regenerative Activities Ameliorated PVT Deprivation‐Induced Vein Graft Failure
Authors: Wang Yinggang , Fu Mingdi , Xiao Weiwei , Zhao Yajing , Yuan Pingping , Zhang Xinchi , Wu Wei 
Published: July 2023

AbstractClinically, arterial injuries are always accompanied with perivascular tissue damage, which may contribute to high failure rate of vein grafts due to intimal hyperplasia and acute thrombosis. In this study, a “perivascular tissue (PVT) deprivation” animal model is constructed to mimic clinical scenarios and identify the contribution of arterial PVT to the success of vein grafts. Proteomics analysis suggests that depriving PVT may exacerbate reactive oxygen species (ROS)‐induced endothelial apoptosis by up‐regulating inflammation response and oxidative stress. Locally administering metformin on vein grafts through 3D‐printed external stent (PGS‐PCL) shows antioxidative and anti‐inflammatory properties to protect cells from ROS invasion, thereafter decreasing acute thrombosis. Moreover, metformin induce rapid regeneration of perivascular adipose tissue in recipient regions, which improves patency by inhibiting intimal hyperplasia. Proteomics, western blot, and in vitro blocking tests reveal that metformin resists endothelial apoptosis through AMPK/mTOR and NFκB signaling pathways. To conclude, PVT deprivation exacerbates inflammatory response and oxidative stress in vein grafts bridging arterial circulation. Metformin‐loaded stent ameliorates “PVT damage” related vein graft failure, and enhances patency of through resisting endothelial apoptosis and regenerating arterial PVAT, offering a promising avenue to improve the success of vein grafts in clinic.
Cu‐Catalyzed C(sp2)−H Bond Aminosulfonylation of Maleimides
Authors: Cen Kaili , Zeng Zhouting , Shen Wangzhen , Feng Yuting , Yan Pingzhi , Wei Jiahao , Hou Qian , Fu Junjie , Xia Xiaotong , Cai Jinhui 
Published: July 2023

AbstractA copper‐catalyzed direct C(sp2)−H bond aminosulfonylation of maleimides is demonstrated. This protocol enables concurrent construction of C(sp2)−N and C(sp2)−SO2 bonds in one‐step and features high efficiency, broad substrate scopes, good functional‐group tolerance, and mild reaction conditions. Preliminary mechanistic studies indicate that the reaction probably involves a radical way. Significantly, this method is applicable to synthesize derivatives of pharmaceuticals such as Desloratadine, Fluoxetine, Atomoxetine, and Maprotiline.
C−C Bond Cleavage of α‐Pyridinium Amides: A Synthetic Approach to Hydantoin Structures
Authors: Takallou Ahmad , Sakhaee Nader , Lotfi Nosood Yazdanbakhsh , Al‐Shidhani Sulaiman , Al‐Siyabi Munir , Mobaraki Akbar , Anwar Muhammad U. , Al‐Harrasi Ahmed 
Published: July 2023

AbstractThis study reports a mild reaction‐condition approach for the direct C−C bond cleavage of amides to form hydantoin structures in the presence of 4‐methylpyridine and a base. This approach presents an amide C−C bond cleavage strategy enabling nucleophilic addition to the amide carbonyl involving a reactive spiro intermediate. A broad spectrum of pseudo peptide Ugi adducts as bifunctional starting materials was synthesized and used in this transformation. The mechanistic pathway of this reaction was investigated using experimental and theoretical studies.
Optical Fiber‐Based Gas Sensing for Early Warning of Thermal Runaway in Lithium‐Ion Batteries
Authors: Chen Xuanren , Gan Lin , Guo Xin 
Published: July 2023

AbstractOwing to constantly increasing energy density and power density, thermal runaway is becoming the most dangerous event in lithium‐ion batteries, while gas sensing can provide the earliest and clearest signals for forewarning the advent of thermal runaway. However, gas‐sensing signals are not included in current battery management systems (BMSs). Especially for the challenging in‐cell sensing, gas sensing demonstrates significant advantages over out‐of‐cell sensing in the aspect of collecting signals precisely and in a timely manner. The integration of gas sensing with batteries is an important and valuable topic. In this review, the necessity and challenge of in‐cell sensing are expounded, the importance and promise of in‐cell gas sensing are highlighted, optical fiber‐based gas sensing technologies for in‐cell applications are summarized, and the engineering issues of integrating sensors with battery system are discussed. The topic of this article deserves more attention and efforts for the development of cell‐level BMSs and safe batteries in future.
Molecular Dynamics Simulation in Compatibility and Mechanical Properties of Chloroprene Rubber/Polyurethane Blends
Authors: Li Yintao , Chen Changwen , He Zhiyu , Wang Yutuo , Xiao Mengqing , Zhou Yuanlin 
Published: July 2023

AbstractFive simulation models of chloroprene rubber (CR)/polyurethane (PU) with different composition ratios (9/1, 8/2, 7/3, 6/4, 5/5) are constructed and simulated using molecular dynamics (MD) simulation. The effects of PU content on blend compatibility and mechanical properties are investigated using solubility parameters, the Flory–Huggins interaction parameter, binding energy, glass transition temperature, and the radial distribution function. The objectives of this study are to develop a computational model based on MD techniques to investigate the compatibility and mechanical properties of CR/PU blends. The results of the solubility parameter indicated that PU has good miscibility with CR. The analysis of interaction parameters, binding energy, glass transition temperature, and radial distribution function show that CR/PU blends with mass ratios of 9/1, 8/2, and 7/3 have good compatibility. Moreover, the analyses of binding energy, pair correlation function, and radial distribution function reveal the reasons for the variation in mechanical properties of the blend systems. Additionally, the correctness of the calculation model and the results are verified by experimental tests and analyses.