bluuebunny/crossref_metadata_2025_split huggingface dataset:
Changes in markers of collagen metabolism in the blood serum of white rats during the filling of femur defects with implants based on polylactide and tricalcium phosphate with allogeneous mesenchymal stem cells
Authors: Gontar N. M. 
Published: September 2023

The use of synthetic materials in combination with osteogenesis stimulators is one of the advanced directions of the development of traumatology. The purpose of the study: based on the analysis of biochemical markers of collagen metabolism in the blood serum of laboratory rats with a femur defect, to evaluate the course of bone remodeling after filling the defect with implants based on polylactide and tricalcium phosphate with simultaneous and delayed administration of allogeneic mesenchymal stem cells (MSCs). On the model of a defect in the metaphysis of the femur in white rats, the indicators of collagen exchange in blood serum were studied: the content of protein-bound, free fractions, the amount of hydroxyproline (HOP), the ratio of the content of protein-bound HOP to free PB/F was calculated. Comparison of the results of different groups was performed using the Student-Fisher method. The difference was considered statistically significant if p<0.05. Filling the defect with implants led to a decrease in the content of protein-bound HOP by 16.69 % and 14.34 % on the 15th and 90th days (p<0.05), an increase in the content of free HOP by 74.96 %; 67.31 % and 56.74 % (p<0.001), the content of the amount of HOP by 25.37 %; 23.66 % and 18.28 % (p<0.05), and reduction of PB/F by 52.20 %; 49.90 % and 45.30 % (p<0.001) relative to intact on the 15th; 30th and 90th days. Addition of MSCs to the implants at the same time as the installation caused a decrease in the content of free HOP by 63.90 %; 54.63 % and 42.76 % on the 15th; on the 30th and 90th days (p<0.001), the total metabolite by 21.87 % and 18.58 % on the 15th and 30th days (p<0.05) and a decrease in PB/F by 47, 50 %; 43.20 %; 37.60 % on the 15th; on the 30th and 90th days (p<0.001) relative to the intact. Postponing the introduction of MSCs increased the content of free HOP by 40.48 % (p<0.001); 20.49 % and 16.58 % (p<0.05) with a lower PB/F by 38.20 %; 25.80 % and 23.40 % (p<0.05) on the 15th; 30th and 90th days relatively intact. When the defect was filled with implants without MSCs, a moderate inhibition of anabolism and rapid activation of collagen destruction was observed. With the simultaneous use of implants and MSCs, the rate of formation and intense destruction of collagen was observed. When the introduction of MSCs was delayed, a moderate rate of destruction was recorded, which most contributed to collagen metabolism.
PHYSICAL AND MATHEMATICAL MODELING OF THE DISTRIBUTION OF LOAD FORCES ON THE FEMINAL COMPONENT OF AN ENDOPROSTHESIS OF THE HIP JOINT UNDER REAL CONDITIONS
Authors: Torchynskyi V. P. , Nizalov T. V. , Shmelyova L. V. , Suprun A. D. 
Published: September 2023

Determination of the factors causing the development of aseptic instability of endoprosthesis components is one of the main tasks of modern traumatology and orthopedics. It is important from a scientific and medical point of view to carry out physical and mathematical modeling of the distribution of load forces and their moments on the femoral component of a hip endoprosthesis. The purpose of the study: to conduct a physical and mathematical modeling of the distribution of load forces on the femoral component of a hip endoprosthesis under real conditions of incomplete axially symmetrical contact of the femoral component of the endoprosthesis and the femur, when the surface of the lower end of the endoprosthesis is not in contact with the surface of the bone. In the work, mathematical modeling of the distribution of point load forces and their moments on the contact surface between the femoral endoprosthesis stem and the bone marrow canal of the femur in real conditions is carried out. For qualitative estimates of point distributions of the load force, based on the analysis of previous results, an estimated empirical formula was obtained for these distributions: g(λ,λ1)=Р(λ,λ1) / 140λ7/2, in which the pressure Р(λ,λ1) is taken in kilograms per square centimeter (kg/cm2), and the point force g(λ,λ1) is in kilograms (kg). It was determined that the best, from the point of view of minimizing the harmful mechanical impact of the prosthesis on the femur, is the situation when the length of the prosthesis stem is not less than half the length of the femur (λ≥0.5). In this case, the values of the point load forces do not exceed 0.1 kg, at least for the length of the area of real contact, which is not less than half the length of the prosthesis stem (λ1≥0.5λ). It has been proven that the use of a prosthesis stem that is less than a third of the length of the femur is not advisable. Since already at the length of the prosthesis stem, which is 30 % of the length of the femur (λ=0.3), point loads increase rapidly and can reach from 0.55 to 1.5 kg depending on the length of the contact area. Such point loads are undesirable for the femur in the area of contact with the prosthesis in terms of the integrity of the femur.
Sentimen Analisis Inisiatif Vaksin Nasional Menggunakan Naïve Bayes dan Laplacian Smoothing Pada Komentar Video Youtube
Authors: Udayana I Putu Agus Eka Darma , Sudipa I Gede Iwan , Risaldi Risaldi 
Published: September 2023

COVID-19 pandemic that has been declared by who in march 2020 Has been Indonesia biggest health crisis end in the decade. WHO said one of the quickest way to end the pandemic is through immunity through vaccine thu's theory is a national vaccine program initiated by the government in the middle of 2021. YouTube is of de facto public space in Indonesia cyberspace for its netizen for various conversation. from gossiping to discuss in public policy YouTube has been a gold mine for social media data mining enthusiast since 2010. but has been not utilized much by Indonesia Academic. do lack of popularity compared to Twitter which has been a media darling what Indonesian Acdemic ever since This research is focused on sentiment analysis pantydeal YouTube about the national vaccine initiation on a news channel in YouTube. This research is primarily consist of naive bayes classifier a a popular algorithm Indonesian data mining enthusiast which has some limitation such as the problem known as zero probability problem and also the use of non-public data which can be fixed by the use of Laplacian smoothing algorithm which when tested Using 100 of random comments as a data testing has resulted in 71% percent of succes rate and when we do a statistical analysis the precision , recall rate and the F-meassurement score of the classifier all resulted in above 75% score which is satisfactory.
Rancang Bangun Alat Nebulizer Ultrasonic Berbasis Arduino Uno
Authors: Guna I Nyoman Satya Indra , Gunawan I Kadek Agus Riki , Arimbawa Putu Eka 
Published: September 2023

Nebulizer merupakan alat yang digunakan untuk terapi yang memasukkan obat kedalam tubuh manusia melalui pernapasan dengan cara mengubah obat menjadi uap atau kabut. Pada tugas akhir ini peneliti merancang sebuah alat nebulizer ultrasonic berbasis arduino uno. Alat ini dapat melakukan pemecahan obat menjadi partikel kecil atau menjadi uap yang dimana dalam alat ini terdapat pemilihan mode low, medium dan high untuk pemilihan frekuensi yang dikeluarkan oleh mist maker yang dimana mode ini akan berpengaruh pada intensitas uap atau kabut yang akan dihasilkan oleh alat. Penelitian ini merupakan penelitian observasi-eksperimental, metode pengumpulan data yang digunakan adalah dengan melakukan pengukuran pada alat ukur yang sudah terkalibrasi. Hasil penelitian ini menunjukkan bahwa alat nebulizer ultrasonic rancang bangun memiliki data rata-rata yaitu pada waktu 10 menit sebesar 600 detik, pada waktu 15 menit sebesar 900 dan pada 20 menit sebesar 1202 detik. Sedangkan rata-rata data frekuensi yang dihasilkan alat nebulizer rancang bangun yaitu pada mode low 12 KHz sebesar 11,5830 KHz, pada mode medium 24 KHz sebesar 24,3190 KHz dan pada mode high 50 KHz sebesar 51,6360 KHz.

Kata kunci: nebulizer ultrasonic, arduino uno dan frekuensi

Nebulizer is a device used for therapy that enters the drug into the human body through breathing by converting the drug into vapor or mist. In this final project, the researchers designed an Arduino Uno-based ultrasonic nebulizer. This tool can break the drug into small particles or into vapor where in this tool there is a selection of low, medium and high modes for the selection of frequencies issued by the mist maker, where this mode will affect the intensity of the steam or mist that will be generated by the device. This research is an observational-experimental research, the data collection method used is by measuring the measuring instrument that has been calibrated. The results of this study indicate that the ultrasonic nebulizer has an average data of 600 seconds at 10 minutes, 900 seconds at 15 minutes and 1202 seconds at 20 minutes. While the average frequency data produced by the design nebulizer is 11.5830 KHz in low mode 12 KHz, 24 KHz medium mode 24.3190 KHz and 50 KHz high mode 51.6360 KHz.

Keywords: ultrasonic nebulizer, arduino uno and frequency
MEMAKSIMALKAN POTENSI ENERGI TERBARUKAN MELALUI PELATIHAN DAN PERAWATAN MODUL SURYA DI DESA KALI BESAR, KECAMATAN KURAU
Authors: Firman Muhammad , Rendi Rendi , Arief Saifullah 
Published: September 2023

Kegiatan ini bertujuan untuk memaksimalkan potensi energi terbarukan melalui pelatihan dan perawatan modul surya bagi masyarakat Desa Kali Besar, Kecamatan Kurau, Kabupaten Tanah Laut. Tujuan utama dari kegiatan ini adalah untuk meningkatkan kesadaran dan keterampilan masyarakat dalam hal pemanfaatan dan perawatan modul surya sebagai sumber energi terbarukan. Metode pelaksanaan yang diberikan adalah memberikan pelatihan dan perawatan modul surya yang sesuai dan baik bagi Masyarakat desa Kali Besar. Prioritas solusi dalam pelatihan ini adalah meningkatkan kesadaran dan pemahaman masyarakat tentang potensi energi terbarukan, serta memberikan keterampilan bagi masyarakat dalam perawatan modul surya. Khalayak sasaran dari pelatihan ini adalah masyarakat Desa Kali Besar, Kecamatan Kurau, Kabupaten Tanah Laut yang membutuhkan pengetahuan dan keterampilan tentang pemanfaatan dan perawatan modul surya.Melalui pelaksanaan kegiatan ini diharapkan mampu memaksimalkan potensi energi terbarukan di Desa Kali Besar, Kecamatan Kurau, Kabupaten Tanah Laut dan membantu memenuhi kebutuhan energi bagi masyarakat setempat. Sambutan Mitra dan masyarakat cukup baik sangat membantu kelancaran pelaksanaan pengabdian. Masyarakat yang mengikuti pelatihan sangat antusias, yang digambarkan dengan pemahaman mereka yang tadinya hanya sekitar 30% menjadi 100%.
PENINGKATAN KAPASITAS DAN MANAJEMEN USAHA NELAYAN ALAT TANGKAP BUBU DI DESA WARULOR KECAMATAN PACIRAN KABUPATEN LAMONGAN
Authors: Rahayu Agung Pamuji , Ali Mukti 
Published: September 2023

Kemampuan SDM usaha perikanan di wilayah pesisir dalam manajemen usaha masih kurang karena sebagian besar berpendidikan rendah, permodalan usaha sebagian besar berasal dari modal sendiri, Manajemen produksi masih sederhana dan pemasaran hasil produksi usaha perikanan secara garis besar dipasarkan dalam bentuk segar dan masih berskala lokal. Oleh karena itu diperlukan upaya pengembangan usaha masyarakat di wilayah pesisir yaitu salah satunya melalui bimbingan teknis manajemen usaha. Minimnya pengetahuan akan pentingnya berkelompok juga menjadi kendala dalam upaya pendampingan kepada Nelayan. Sehingga perlu dilakukan upaya pendampingan dari instansi terkait dan akademisi guna merubah pola pikir dan nasib nelayan untuk menuju kehidupan ekonomi yang lebih baik. Sasaran kegiatan ini adalah pelaku utama/nelayan alat tangkap Bubu yang tergabung dalam organisasi mitra Kelompok Usaha Bersama “Makmur Sejahtera” di Desa Warulor, Kecamatan Paciran, Kabupaten Lamongan. Metode pendekatan yang digunakan yaitu pemetaan potensi lokasi, penyuluhan, pelatihan dan pendampingan manajemen usaha nelayan Desa Warulor Kecamatan Paciran Kabupaten Lamongan. Hasil pengabdian masyarakat yaitu masyarakat sadar akan pentingnya berkelompok sesuai KepMen KP No.14 tahun 2012 tentang penumbuhan dan pengembangan kelompok pelaku utama dan usaha Kelautan dan Perikanan. Selanjutnya masyarakat nelayan dapat memahami tentang manajemen usaha dalam upaya meningkatkan pendapatan dan kesejahteraan ekonomi.
Four Points Block Method with Second Derivative for Solving First Order Ordinary Differential Equations
Authors: Sabah Jasim Niran , Yousif Turki Mohammed , Mechee Mohammed  S. , Smeein Shrooq Bahjat 
Published: September 2023

In this study, we devised 4-point implicit block (New 4pb) approaches that take advantage of second derivatives. The aim provides is more accurate and quicker numerical solutions to first - order ordinary differential equations (ODEs). Whereas the properties of the (New 4pb) method such as the order and zero-stability have been discussed. After that, the approaches are applied to a collection of first-order (ODEs). In addressing the set of test problems, numerical results clearly indicate that the newly proposed systems outperformed previous, well-known existing methods.
A Novel Integral Transform :INEM - Transform
Authors: Zamil Intidhar , Kuffi Emad Abbas 
Published: September 2023

In this paper, we present a novel transform namely INEM – Transform , involving a lot of potential new or known transform basic characteristics of the new transform were examined in this work as special cases., authors first derived the INEM – transform of basic mathematical functions ,theorem of linearity ,theorem of derivatives and the definition of inverse formula .a novel transformation used to address specific initial value problems of higher order ,some illustrative examples, and use of application in two applications: finding the blood glucose concentration and finding the aortic pressure presented in this work.
Criteria for evaluating the work of the internal audit unit for the purposes of financial control of managers of state budget funds
Authors: SHCHYRSKA O. 
Published: September 2023

The article outlines the essence of the audit processes of state budget managers. The possibility of ensuring high-quality internal audit as a factor in providing information for the purposes of state financial audit and performance audit is considered. The issue of ensuring and implementing such control is the subject of regulatory attention. According to the norms of the current legislation of Ukraine, internal audit must be introduced in the activities of budget funds managers. Such rules apply to managers of state budget funds and local budgets, which ensures the transparency of management of budget funds, management responsibility of managers of different levels, responsibility for ensuring the effective operation of the budget institution.
It is stated that in accordance with the current legislation, the external assessment of the quality of the functioning of the internal audit is organized and conducted by the Ministry of Finance of Ukraine. The manager of budget funds in the person of the head forms an independent structural unit of internal audit, subordinated and accountable directly to this head.
The main parameters of the work of the internal audit unit are structured, which determine the specifi cs of quality control and the state of internal control of managers of budget funds within the framework of efficiency audit during check ups by the Accounting Chamber and the State Audit Service.
25 Years of Experience in Household Sample Surveys in the Official Statistics of Ukraine: Main Assets, Problems, Prospects
Authors: Sarioglo V. 
Published: September 2023

Since 1998, the state statistics of Ukraine has accumulated a huge experience in organizing and conducting household sample surveys in accordance with international recommendations and standards. Nowadays, the harmonized system of surveys includes the Household Living Conditions Survey, the Labor Force Survey and the Survey of Household Agricultural Activities in rural areas. About 100,000 households are surveyed annually, which represent all private households in various samples of these surveys. A significant number of specialists with the necessary knowledge and skills have been trained in the State Statistics Service of Ukraine (hereinafter - SSSU), territorial bodies of the SSSU.
The article considers the main characteristics of the SSSU experience in the field of methodology and practice of organizing and conducting the household sample surveys, collecting and processing surveys’ data, statistical indicators estimation. The strengths and weaknesses of the acquired experience, potential directions for improvement of surveys, risks that may affect the quality of their results in the future, plans for the development of the system of sample surveys and the use of new methods of data collecting and processing are discussed.
It is noted that the acquired experience made it possible to approach in 2021 to the development of the basis for introduction of such actual survey in Ukraine as the EU statistics on income and living conditions (EU-SILC), to foresee the use of new data collection technologies CAPI, CATI and CAWI without any particular problems.
At the same time, it is shown that some important methodologies regarding the estimation of indicators based on survey results have not been implemented. It is noted that an urgent problem for the SSSU is the use of "big data" in household surveys, which provides the opportunity of significantly reducing the burden on households during the survey, improving the completeness and timeliness of information about them, reducing costs for survey providing, etc. Such data could provide also estimation of certain important statistical indicators during the war. The risks of an accelerated transition for conducting the state household sample surveys mainly using CATI and CAWI technologies are discussed, related to the possibility of a significant deterioration in the quality of the survey results due to the lack of relevant skills of the SSSU specialists, insufficient level of Internet use by the population, lack of population and household registers with quality data in Ukraine, etc.
Statistical Assessment of Sustainable Urban Water Ecosystems
Authors: Kobylynska Т. V. , Motuzka O. M. , Kobylynskyi V. M. 
Published: September 2023

The integrated character of Sustainable Development Goals (SDGs) reflects interconnectedness of water systems and their rich biodiversity, supplying communities with foods, clean water and air, mineral resources, and regulating their welfare and economic growth. The increasing awareness of the importance of public access to water ecosystems can have a positive impact on these ecosystems and encourage partnerships to responsible management of these resources and reactions on water crises through improvements of skills and competencies.
The article highlights that the development of partnership relations for the achievement of SDGs is a target 17 of SDGs. An assessment of global and national objectives and indicators laid in the basis of the assessment of a progress on the way to the sustainable environmental accounting and the development of urban water ecosystems is given.
It should be noted that the statistical information in divided into four groups which data are used in monitoring of the green economy performance: statistical base of nature assets; environmental and resource productivity of economy; environmental quality of life; economic capabilities and political reactions.
The analysis showed the importance of the environmental inclusion of respective spatial groups. Aggregations based on drainage basin or ecosystem can provide better understanding of the environmental dimension of many interconnections defined for sweet water and seawater ecosystems. It is expected, however, that the applicable methods and tools will be elaborated in parallel, to simplify data use by politicians. A deeper understanding of interconnections of SDGs will enable for enhancing the efficiency of political measures.
It is concluded that the sustainable development and the 2030 Agenda for Sustainable Development can be achieved only by implementing the overall sectoral approach that will combine the tendencies of the indicators related with the environment with robust policy analysis. This requires the cohesion of all the sustainable development policy dimensions on the basis of the integrated approach, to ensure the elaboration of complementary strategies and to avoid compromises.
The Employment in Ukraine and the World: The Condition and Prospects
Authors: Gerasymenko S. S. , Нerasymenko V. V. 
Published: September 2023

The article is devoted to analysis of tendencies in the employment, its patterns and determining factors in the world and selected countries, problems of the effective population’s employment and prevention of the massive unemployment. The high level of unemployment and large scales of the poverty, small numbers of job vacancies along with large numbers of unemployed per job vacancy are explicit negative features of the domestic and regional labor markets. A problem of special importance is the unemployment that has gained large scales in nearly all the strata of the population, worsened their welfare and life standards, to become a problem of global dimension.
Analysis and solutions of unemployment problems have always drawn the increased attention of researchers in economics throughout the history of economic thought. The search for levers and tools allowing for eliminating this phenomenon with reliance on the total employment mechanism has been central to all the economic theories. A review of scientific developments focused on the essence and problems of unemployment shows the variety of approaches to the solution of problems associated with this phenomenon.
In view of the above, assessment, modelling and forecasting of the labor market has a leading position in socio-economic studies. The article contains the author’s substantiation of the feasibility of assessment and analysis of the level and dynamics of unemployment as an important component of the labor market under the impact of factors such as the economic mode and its structural change, the technical and organizational level of entrepreneurship, the balance between the structure of production means and workforce, the overall performance of business management system. An analytical review and comparison of the contents of social programs for protection of unemployed in selected countries is made.
The problem of assessment and determining the patterns of factor impact on the variations of unemployment level is addressed in the article on the basis of data on the dynamics of real gross domestic product and inflation, used for the aggregated assessment of the current performance of a national economy. It is recommended that the foundations of the policy on stabilization of prices, payment balance and structural transformations be developed in the future, given their impact on the employment and the income of the whole population and their groups, which consequence is supposed to be improvement of the labor market structure, unemployment reduction in particular. Determining the degree and vector of these measures’ impact on a national economy will be the next phase of the study.