bluuebunny/crossref_metadata_2025_split huggingface dataset:
Demography, common disorders and mortality of Boxer dogs under primary veterinary care in the UK
Authors: O’Neill Dan G. , Skipper Alison M. , Barrett Kate , Church David B. , Packer Rowena M. A. , Brodbelt Dave C. 
Published: June 2023

Abstract
Background
The Boxer is a popular dog breed with a distinctive appearance. However, the breed has been linked with several health conditions, some of which have been associated with its moderately brachycephalic conformation and its white colouration. Anonymised primary-care veterinary clinical records were explored to extract data on the demography, common disorders and mortality of Boxers in the UK in 2016.

Results
The study population of 336,865 dogs included 3,219 (0.96%) Boxers, of which 10.71% were recorded as white. The mean adult bodyweight was 30.43 kg (SD 5.73 kg). Annual disorder counts did not differ statistically between the sexes or between white and non-white Boxers. The most prevalent fine-level precision disorders were otitis externa (n = 230, 7.15%), epulis (188, 5.84%), corneal ulceration (161, 5.00%) and periodontal disease (149, 4.63%). Of the 34 most common fine-level disorders, none differed in prevalence between white and non-white dogs. The most prevalent disorder groups were skin disorder (n = 571, 17.74%), neoplasia (457, 14.20%) and ear disorder (335, 10.41%). White Boxers had higher prevalence than non-white Boxers for two disorder groups: dental disorder and brain disorder. The median longevity of 346 Boxers that died during the study was 10.46 years (IQR 9.00–11.98, range 2.76–18.00). Median longevity did not differ statistically between the sexes or between white and non-white Boxers. The most common grouped causes of death were death – unrecorded cause (n = 73, 21.10%), neoplasia (43, 12.43%) and brain disorder (33, 9.54%).

Conclusions
There was minimal evidence of substantial health differences between white and non-white Boxers. Among the four most common disorders recorded in Boxers, two were typically common across all types of dogs (otitis externa and periodontal disease) while two suggested strong predispositions for the Boxer breed (epulis and corneal ulceration), showing the value of eliciting breed-specific disorder patterns for insights for potential health reforms. The overall longevity of Boxer dogs was consistent with other breeds of similar body size.
Posterior stability of the shoulder depends on acromial anatomy: a biomechanical study of 3D surface models
Authors: Hochreiter Bettina , Beeler Silvan , Hofstede Simon , Sigrist Bastian , Snedeker Jess G. , Gerber Christian 
Published: June 2023

AbstractPurposePrimary glenohumeral osteoarthritis is commonly associated with static posterior subluxation of the humeral head. Scapulae with static/dynamic posterior instability feature a superiorly and horizontally oriented acromion. We investigated whether the acromion acts as a restraint to posterior humeral translation.MethodsFive three‐dimensional (3D) printed scapula models were biomechanically tested. A statistical shape mean model (SSMM) of the normal scapula of 40 asymptomatic shoulders was fabricated. Next, a SSMM of scapular anatomy associated with posterior subluxation was generated using data of 20 scapulae (“B1”). This model was then used to generate three models of surgical correction: glenoid version, acromial orientation, and acromial and glenoid orientation. With the joint axially loaded (100N) and the humerus stabilized, an anterior translation force was applied to the scapula in 35°, 60° and 75° of glenohumeral flexion. Translation (mm) was measured.ResultsIn the normal scapula, the humerus translates significantly less to contact with the acromion compared to all other configurations (p < .000 for all comparisons; i.e. 35°: “normal” 8,1 mm (± 0,0) versus “B1” 11,9 mm (± 0,0) versus “B1 Acromion Correction” 12,2 mm (± 0,2) versus “B1 Glenoid Correction” 13,3 mm (± 0,1)). Restoration of normal translation was only achieved with correction of glenoid and acromial anatomy (i.e. 75°: “normal” 11 mm (± 0,8) versus “B1 Acromion Correction” 17,5 mm (± 0,1) versus “B1 Glenoid Correction” 19,7 mm (± 1,3) versus “B1 Glenoid + Acromion Correction” 11,5 mm (± 1,1)).ConclusionsPersistence or recurrence of static/dynamic posterior instability after correction of glenoid version alone may be related to incomplete restoration of the intrinsic stability that is conferred by a normal acromial anatomy.Level of Evidence Vbiomechanical study
Diel variability in the vertical distribution of coastal barnacle larvae in the Bay of Cartagena, Chile
Authors: Bonicelli Jessica , Jeneral María José , Bularz Bryan , Weidberg Nicolas , Plummer Katalin A. , Calderón Ricardo , Cifuentes Ursula , Alarcón Darly , Navarrete Sergio A. 
Published: June 2023

Abstract
Background
Vertical distribution of zooplankton is an important biological factor that can modulate zooplankton transport, dispersal, and survival in the ocean. Seawater temperature and the associated formation of a thermocline can affect the spatial distribution of organisms in the water column and possibly modulate larval vertical distribution in coastal waters. In this study, we examined larval vertical distribution over small spatial scales where environmental conditions could exhibit strong and fairly predictable variability.

Methods
Diel variation in vertical distributions of barnacle larvae across the thermocline was characterized within the Bay of Cartagena of central Chile. Two intensive 21- and 24-h surveys were conducted in the northern (ECIM) and southern (CTGN) extremes of the bay in summer 2016 and spring 2017. In each survey, vertical tows were conducted at both sites every 3 h above and below the thermocline.

Results
During summer 2016, larval vertical distribution differed between taxa (balanids and verrucids), barnacle stages (nauplii, cyprids), and sites within the bay. Of all taxa analyzed Balanid nauplii at ECIM were more abundant in the bottom layer during the day and at the surface during the night, suggesting they can control their vertical distribution and follow a diel pattern.Acording to the results all barnacle larvae were found in diferent positions in the water column between day and night during periods of high stratification in this survey.. In spring 2017 all barnacle larvae were confined to the upper layer, despite the strength of stratification, potentially as a result of the intrusion of hypoxic water (< 2 mL L−1) at the bottom, which reached up to around 5 m deep.

Conclusions
We conclude that diel vertical distribution is not uniform across different barnacle larvae taxa and stages within the Bay of Cartagena and is not affected by stratification. Of all the taxa analyzed, only balanid nauplii showed a pattern of diel vertical migration across the thermocline under certain hydrographic conditions.
Abrupt increased serum creatinine in a hyperferritinemia patient treated with deferoxamine after cord blood transplantation: a case report with literature review
Authors: Nakayama Hirokazu , Kamoda Yoshimasa , Tanuma Michiya , Kato Toshiaki , Usuki Kensuke 
Published: June 2023

Abstract
Background
Erythrocyte transfusion is an indispensable component of supportive care after hematopoietic stem cell transplantation (HSCT). However, HSCT recipients are susceptible to the development of acute kidney injury (AKI) with multifactorial causes. We report a case of a rapid elevation in serum creatinine associated with deferoxamine after cord blood transplantation (CBT).

Case presentation
A 36-year-old Japanese male diagnosed with relapsed Philadelphia-positive acute lymphoblastic leukemia received CBT. At day 88 post-CBT, multidrug-resistant Pseudomonas aeruginosa (MDRP) was isolated from urine culture. Subsequently, colistin 200 mg/day was administered parenterally for treatment of epididymitis from day 91 to 117 post-CBT. Despite concomitant administration of potential nephrotoxic agents such as piperacillin-tazobactam, acyclovir, and liposomal amphotericin B, no development of AKI was observed during this period. At day 127 post-CBT, MDRP was detected in blood and urine cultures, and colistin 200 mg/day was re-started parenterally. Due to extremely higher ferritin level, deferoxamine was administered intravenously at day 133 post-CBT. While serum creatinine was 1.03 mg/dL before starting deferoxamine, the level increased to 1.36 mg/dL one day after commencing deferoxamine (day 134 post-CBT), and further increased to 2.11 mg/dL at day 141. Even though colistin was discontinued at day 141 post-CBT, serum creatinine continued to increase. Deferoxamine was withdrawn at day 145 post-CBT, when serum creatinine peaked at 2.70 mg/dL. In addition, no cylinduria is observed during the period of development of AKI. In adverse drug reaction (ADR) assessment using Naranjo probability score, the scores of 3 in deferoxamine and 2 in colistin, respectively, indicated “possible” ADR. However, while colistin-associated AKI manifested early onset, recovery time within 2 weeks after discontinuation and development of cylinduria, this case was discordant with the properties. Furthermore, in the literature review, development of AKI within 1 day, including sudden increase in serum creatinine or abrupt reduction in urine volume, was reported in 3 identified cases.

Conclusions
We considered the rapid creatinine elevation to be the result of deferoxamine rather than ADR caused by colistin. Therefore, careful monitoring of kidney function is required in recipients of HSCT treated with deferoxamine.
The microbiome of Riccia liverworts is an important reservoir for microbial diversity in temporary agricultural crusts
Authors: Wicaksono Wisnu Adi , Semler Bettina , Pöltl Martina , Berg Christian , Berg Gabriele , Cernava Tomislav 
Published: June 2023

AbstractBackgroundThe microbiota of liverworts provides an interesting model for plant symbioses; however, their microbiome assembly is not yet understood. Here, we assessed specific factors that shape microbial communities associated withRicciatemporary agricultural crusts in harvested fields by investigating bacterial, fungal and archaeal communities in thalli and adhering soil from different field sites in Styria and Burgenland, Austria combining qPCR analyses, amplicon sequencing and advanced microscopy.ResultsRiccia spec. div.was colonized by a very high abundance of bacteria (101016S rRNA gene copies per g of thallus) as well as archaea and fungi (108ITS copies per g of thallus). EachRicciathallus contain approx. 1000 prokaryotic and fungal ASVs. The field type was the main driver for the enrichment of fungal taxa, likely due to an imprint on soil microbiomes by the cultivated crop plants. This was shown by a higher fungal richness and different fungal community compositions comparing liverwort samples collected from pumpkin fields, with those from corn fields. In contrast, bacterial communities linked to liverworts are highly specialized and the soil attached to them is not a significant source of these bacteria. Specifically, enrichedCyanobacteria, BacteroidetesandMethylobacteriasuggest a symbiotic interaction. Intriguingly, compared to the surrounding soil, the thallus samples were shown to enrich several well-known bacterial and fungal phytopathogens indicating an undescribed role of liverworts as potential reservoirs of crop pathogens.ConclusionsOur results provide evidence that a stable bacterial community but varying fungal communities are colonizing liverwort thalli. Post-harvest, temporary agricultural biocrusts are important reservoirs for microbial biodiversity but they have to be considered as potential reservoirs for pathogens as well.
Effects of a High-Volume 7-Week Pectoralis Muscle Stretching Training on Muscle Function and Muscle Stiffness
Authors: Reiner Marina , Gabriel Anna , Sommer Daniel , Bernsteiner Daniel , Tilp Markus , Konrad Andreas 
Published: June 2023

Abstract
Background
There is evidence that high-volume static stretching training of the lower limbs can increase the range of motion (ROM) while decreasing muscles stiffness. However, to date, there is no evidence on the effects of upper limb stretching training or its effect mechanism. Therefore, this study aimed to investigate the effects of a comprehensive 7-week static stretching training program of the pectoralis major muscle (PMa) on glenohumeral joint ROM, muscle force, and muscle stiffness.

Methods
Thirty-eight healthy, physically active participants (23 male, 15 female) were randomly assigned to either the PMa-static stretching intervention (PMa-SS) group or the control group. The PMa-SS group performed a 7-week intervention comprising three sessions a week for 15 min per session, including three static stretching exercises of the PMa for 5 min each. Before and after the intervention period, shoulder extension ROM, muscle stiffness of the PMa (pars clavicularis), and maximal voluntary isometric contraction (MVIC) peak torque (evaluated at both long (MVIClong) and short (MVICshort) muscle lengths) were investigated on a custom-made testing device at 45° shoulder abduction.

Results
In the PMa-SS group, the shoulder extension ROM (+ 6%; p < 0.01; d = 0.92) and the MVIClong (+ 11%; p = 0.01; d = 0.76) increased. However, there were no significant changes in MVICshort or in PMa muscle stiffness in the PMa-SS group. In the control group, no changes occurred in any parameter.

Conclusion
In addition to the increase in ROM, we also observed an improved MVIC at longer but not shorter muscle lengths. This potentially indicates an increase in fascicle length, and hence a likely increase in sarcomeres in series.
Individual Changes in Respiratory Compliance Upon Immersion May Predict Susceptibility to Immersion Pulmonary Edema
Authors: Castagna Olivier , Druelle Arnaud , Michoud Guillaume , Prevautel Thibaut , Lacour Jean-René 
Published: June 2023

Abstract
Background
Immersion pulmonary edema (IPE) is a frequent diving accident, and it is the primary cause of hospitalization for young military divers during training. The objective of this study was to identify immersion-induced parameters predicting individual susceptibility to IPE.

Methods
Eighteen experienced male divers having completed at least 100 dives were recruited. Eight divers had previously been hospitalized for IPE (IPE), and the other ten had never developed IPE (non-IPE). The two groups were matched for age, BMI, and number of dives performed. Ventilatory function and overall compliance of the respiratory system (Crs) were measured on land and during head-out-of-water immersion. Subjects also performed 30 min of fin swimming in a channel at 33 m min−1. Following this exercise, the presence of extravascular lung water, revealed by ultrasound lung comets (ULC), was assessed.

Results
In the whole group, the decrease in Crs upon immersion correlated with the immersion-induced alterations to expiratory reserve volume, ERV (r2 = 0.91; p < 0.001), inspiratory reserve volume, IRV (r2 = 0.94; p < 0.001), and tidal volume, Vt, changes (r2 = 0.43; p < 0.003). The number of ULC correlated strongly with immersion-induced changes in ventilatory function (r2 = 0.818; p < 0.001 for ERV, r2 = 0.849; p < 0.001 for IRV, r2 = 0.304; p = 0.0164 for Vt) and reduced Crs (r2 = 0.19; p < 0.001).
The variations of ERV, IRV, and Crs at rest induced by head-out-of-water immersion and the number of ULC measured after swimming for 30 min were significantly greater in IPE subjects.

Conclusion
In the face of similar immersion stresses, the extent of alterations to ventilatory function and the number of ULCs were very different between individuals but remained statistically correlated. These parameters were significantly greater in divers with a history of IPE. Alterations to pulmonary function and, in particular, to pulmonary compliance induced by head-out-of-water immersion, through their effects on work of breathing appear to allow the identification of divers with a greater susceptibility to developing IPE. Measurement of these parameters could therefore be proposed as a predictive test for the risk of developing IPE.
Modeling and performance analysis of solar parabolic trough collectors for hybrid process heat application in Kenya’s tea industry using system advisor model
Authors: Akello Philip O. O. , Saoke Churchil O. , Kamau Joseph N. , Ndeda Jared O. H. 
Published: June 2023

AbstractAmong the Concentrated Solar Collector (CSC) technologies, Parabolic Trough Collector (PTC) is the most mature and commercialized CSC technology today. Currently, solar PTC technology is mainly used for electricity generation despite its huge potential for heating, especially in industrial process heat (IPH) applications. Though the technology is well-developed and successfully used in many developed countries, there is barely any development in Kenya. This paper studies the techno-economic feasibility of a solar PTC-assisted tea drying process in one tea factory that currently relies on biomass for process heat, in the tea producing area of Kericho, Kenya. The plant integrating parabolic troughs is modelled and a yearly simulation performed using System Advisor Model (SAM) software. The weather data are derived from ground measurements at Kericho meteorological weather station. SAM is used to model the impact of the principal design parameters, i.e., solar multiple (SM), thermal energy storage (TES) and hybridization percentages, on solar–biomass plant configurations, and to reveal the optimum case. The studied impacts are linked to the annual energy production and the optimal size which minimizes the levelized cost of heat (LCOH). Analysis of monthly variations of energy production by the solar PTC reveals that even when the solar system is designed to its maximum capacity (SM of 3 and TES of 24 h), some months will still require hybridisation with biomass to fully meet the energy demand. TES must also be incorporated in the solar PTC design to maximise on energy production. The hybrid solar–biomass plant with TES provides optimal performance when SM is 1.8 and TES is 24 h. This results in LCOH of 1.85 US cents/kWh, which is 25% cheaper than using biomass only as is the current practice. Furthermore, integration of solar PTC has a positive impact on carbon footprint and considerably reduces annual greenhouse gas (GHG) emissions by 9817 tons of CO2-eq, and annual fuel wood consumption by 16,462 m3 (equivalent to 23.51 acres of mature grown trees).
A global network of scholars? The geographical concentration of institutes in migration studies and its implications
Authors: Piccoli Lorenzo , Ruedin Didier , Geddes Andrew 
Published: June 2023

AbstractThe study of international migration and responses to it has experienced rapid growth in the last three decades: an institutionalisation of migration studies. This paper identifies and specifies infrastructural and semantic elements of institutionalisation by establishing a global Directory of Migration Research Institutions identifying 282 institutes focused on migration research that were operative between 1945 and 2020. We observe a clear geographical concentration in the Americas and Europe and find that most institutes are in countries with higher economic development (GDP) and net immigration (not emigration). Using this evidence, we suggest that the institutionalisation of migration studies is driven by concerns and ideas produced in high-income ‘destination’ countries. We thus show that uneven knowledge production in migration studies is not only caused by exclusive categories, language, or journal policies, but also by a structural problem at an earlier stage: because of fewer resources invested in the creation of institutionalised academic knowledge structures, lower income countries have fewer possibilities to shape the semantic features of the field of migration studies, by which we mean the identification of subjects of interest, concepts, narratives, and priorities.
Feasibility, credence, and usefulness of out-of-office cuffless blood pressure monitoring using smartwatch: a population survey
Authors: Jang Yongjun , Seo Jong-Mo , Ihm Sang-Hyun , Lee Hae Young ,   on behalf of the Korean Society of Hypertension
Published: June 2023

Abstract
Background
Cuffless blood pressure (BP) measurement, enabled by recent advances in wearable devices, allows for BP monitoring in daily life. This study aims to evaluate the feasibility, cresdence, and usefulness of cuffless BP monitoring through a population survey.

Methods
During the "Daily BP Measurement with Your Galaxy Watch" campaign held by the Korean Society of Hypertension, participants were asked to share their experiences with cuffless BP measurement using a smartwatch application through an online survey. The questionnaire included questions about age, underlying medical conditions, smartwatch utilization, experience with BP calibration, the reliability of BP values measured by a smartwatch, and willingness to use the BP monitoring function in the future.

Results
A total of 1071 participants responded to the survey. The largest age group (decile) was 50-59 years old (33.3%), followed by 40-49 years old (29.9%). Although nearly half of the participants (47.5%) had no chronic diseases, 40.1% reported having hypertension. BP monitoring was the most frequently utilized smartwatch function (95.8%), followed by heart rate measurement (87.1%). 31.8% of participants reported that BP values measured by the smartphone application were "very accurate and helpful," while 63.5% rated them as "slightly lower (44.4%)" or "higher (19.1%)" compared to the standard home BP monitoring device. 93% of the participants reported utilizing the BP monitoring function at least once a week. Regarding the BP calibration process, most participants (93.9%) calibrated the BP measurement application themselves, and 50.8% rated the difficulty level as "very easy."

Conclusion
Cuffless BP measurement using a smartwatch application was feasible in the general population, including the self-calibration process. However, the satisfaction level in terms of accuracy is still modest, indicating a need for further development.
PRO-Act: a healthcare provider workshop outlining the added value of implementing PROs in routine HIV practice
Authors: Antunes António , Racha-Pacheco Ricardo , Esteves Catarina , Tavares Ana , Mendez Josefina , Pacheco Patrícia , Short Duncan 
Published: June 2023

AbstractPatient Reported Outcomes (PROs) are an evidenced way of adding value to routine clinical care. As a source of unique information on the effect of a medical condition and its treatment from the patients’ perspective (Mercieca-Bebber et al. in Patient Relat Outcome Meas 9: 353–367,https://doi.org/10.2147/PROM.S156279, 2018), PROs allow for an improved assessment in routine clinical care of symptoms, side effects, functional outcomes (physical, sexual, social, emotional, cognitive functioning), and health-related quality of life (HRQoL). By helping to align healthcare providers’ interventions with what matters most to the patient, PROs contribute to the individualized choice of Anti-Retroviral Therapy (Carfora et al. in PLoS ONE 17(4): e0267030,https://doi.org/10.1371/journal.pone.0267030, 2022) as a paramount component of tailored and person-centred care management, in routine clinical practice. This article outlines a practical framework and process tested in Portugal to raise awareness of PROs’ added value, and to help guide first steps in the implementation and seamless integration of PROs, in routine HIV care.