bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Theoretical Study of Structural, Electronic, and Vibration Properties of Acetylcholine Chloride and Bromide
Authors: Gordienko Kirill , Gordienko Aleksei , Zhuravlev Yurii 
Published: December 2022

The ever-growing capabilities of computing systems and algorithms make the first-principle methods extremely important in such research fields as biologically active compounds and complex biological systems. They also facilitate the target search and prediction of new forms. The purpose of the study was to define the structural parameters and basic electronic and vibration characteristics of crystal acetylcholine halides (ACh-Hal).
The study featured acetylcholine chloride and bromide (ACh-Hal). The theoretical analysis was based on the density functional theory (DFT) with gradient Perdew-Burke-Ernzerhof exchange-correlation functional (PBE) and a semi-empirical scheme for dispersion-accounting density functional (DFT+D3).
The calculations made it possible to define the optimized parameters of the crystal lattice: a = 9.765 Å, b = 15.217 Å, c = 6.274 Å for orthorhombic acetylcholine chloride (ACh-Cl); a = 10.883 Å, b = 13.304 Å, c = 7.077 Å, 109.21° for monoclinic bromide (ACh-Br). The calculations also revealed atomic coordinates, bond lengths, valence, and torsion angles. As for the electronic structure, ACh-Hal proved to be dielectrics with a band gap of 4.734 and 4.405 eV. The effective charges of carbon atoms were highly anisotropic. The calculated vibration spectra confirmed the experimental data in the entire interval, while the dependence on the mass of the anion was especially prominent in the region of lattice vibrations.
The first-principle DFT+D3 scheme made it possible to obtain reliable data on the basic properties of complex organic and biologically active systems.
Spices, Herbs, and Essential-Oil Plants: Yield and Fatty Acid Composition of Seeds
Authors: Sachyuka Tatsiana , Feskova Alena , Kovalenko Natallia , Supichenko Galina , Bosak Viktar 
Published: December 2022

Spices, herbs, and essential-oil plants provide a lot of marketable products, e.g., green mash, seeds, essential oils, etc. These raw materials find application in food industry, pharmacy, perfumery, traditional and folk medicine, landscape gardening, etc. The research objective was to test some new varieties of spices, aromatic herbs, and essential oil crops for their yield and fatty acid composition.
The study featured new varieties of medicinal hyssop (Hyssopus officinalis L.), oregano (Origanum vulgare L.), basil (Ocimum basilicum L.), tulsi (Ocimum tenuiflorum L.), garlic chives (Allium odorum L.), rue (Ruta graveolens L.), blue fenugreek (Trigonella caerulea (L.) Ser.), and big-root geranium (Geranium macrorrhizum L.). The yield of green mass and seeds was studied on the experimental field of the Belarusian State Agricultural Academy according to standard methods. A set of standard laboratory procedures made it possible to define the content of crude fat, while the fatty acid composition of seed lipids was studied by gas chromatography in extracts of methyl esters of fatty acids.
The green mass yield was 150–280 c/ha, whereas the seed yield was 0.5–4.0 c/ha; the crude fat content was 1.15–3.37 and 1.62–9.81%, respectively. The fatty acid composition of seed lipids included caprylic, palmitic, stearic, oleic, linoleic, and α-linolenic acids. The highest content of polyunsaturated essential fatty acids represented by linoleic and α-linolenic acids was observed in oregano (86.74–87.27%), hyssop (76.41–85.96%), tulsi (85.67%), basil (72.52–80.72%), rue (78.04%), and blue fenugreek (72.96%).
The specified yield and fatty acid composition provided a complete assessment of spices, herbs, and essential-oil plants with the prospect of their use as part of new functional products.
Rheological Properties of Mayonnaise with Non-Traditional Ingredients
Authors: Bredikhin Sergey , Martekha Alexander , Andreev Vladimir , Kaverina Yuliya , Korotkiy Igor 
Published: December 2022

Rheological measurements are used in the food industry to determine physical characteristics of raw materials, as well as semi-finished and finished products. We aimed to study the effects of ingredients and homogenization parameters on the rheological properties of mayonnaise prepared with pumpkin and rice oils, as well as various honeys.
Mayonnaise samples were prepared with non-traditional ingredients, namely cold-pressed pumpkin seed oil, refined rice oil, and four varieties of honey (acacia, linden, forest, and spring). The samples were made in the traditional way on an Ultra Turrax T25 IKA homogenizer (3500–24 000 rpm). The rheological properties of honey and mayonnaise were determined on a Brookfield rotational viscometer.
Forest honey had the highest viscosity, while linden honey had the lowest viscosity, compared to the other honeys. The sample of mayonnaise with forest honey had the highest effective viscosity (3.427 Pa·s) and consistency (101.26 Pa·sn). The use of whey powder provided mayonnaise with the most optimal rheological parameters. Of all carbohydrates, inulin HD had the best effect on the consistency of mayonnaise, with effective viscosity of 2.801 ± 0.001 Pa·s and a flow index of 0.2630 ± 0.0020. Disaccharides provided mayonnaise with higher viscosity and consistency than monosaccharides. Mayonnaise with fresh egg yolk had higher viscosity (2.656 ± 0.002 Pa·s) and consistency (65.640 ± 0.004 Pa·s) than the samples with other egg products. The rheological characteristics of mayonnaise were also determined by the homogenization time and rotor speed. Increasing the time from 2 to 4 min at 10 000 rpm raised the emulsion’s viscosity and consistency from 6.253 to 8.736 Pa·s and from 77.42 to 134.24 Pa·sn, respectively, as well as reduced the flow index from 0.2628 to 0.1995. The rotor speed of 10 000–12 000 rpm was optimal for mayonnaise with pumpkin and rice oils and honey.
The studied samples of mayonnaise with pumpkin and rice oils, as well as honey, belong to non-Newtonian systems and pseudoplastic fluids. The empirical flow curves can be adequately described by the Herschel-Bulkley model. Our results can significantly increase the efficiency of mayonnaise production, improve its quality, and reduce production costs.
Quality Indicators of Agaricus bisporus after Ultraviolet Treatment
Authors: Kondratenko Vladimir , Posokina Natalia , Fedyanina Natalia , Karastoyanova Olga , Korovkina Nadezhda 
Published: December 2022

Ultraviolet treatment increases the shelf life of plant products. It inhibits the changes in the quality indicators of raw materials that are responsible for storage capacity. The research objective was to establish qualitative indicators for champignons (Agaricus bisporus) after ultraviolet treatment.
Fresh champignons were placed in plastic trays and sealed in plastic bags. The samples were treated with ultraviolet radiation in ranges A, B, and C. After that, they were stored in a refrigerator at 4 ± 2°C for 16 days, i.e., until the end of storage period. The quality indicators underwent a paired two-sample test, which defined the equality/inequality of variances in replicates and equality/inequality of means at a given error probability (α).
The obtained indicators characterized the degradation of mushroom plant tissue after ultraviolet treatment during storage: texture, moisture content, weight loss, soluble solids, pH, lightness, and color. The authors developed a new approach to determine significant changes in the quality indicators and estimated probability values. For each range, they established the most effective dose at α = 0.05 and 0.1. All the indicators proved significant for range A samples at 327.8–800.0 J/m2 and α = 0.05; all indicators were significant except weight loss in the range from 219.5 to 800.0 J/m2 at α = 0.1. For range B samples, pH, color, and lightness were significant at 104.6–200.0 J/m2 and α = 0.05; all but mass loss and texture were significant at 172.2–200.0 J/m2 and α = 0.1. For range C samples, pH, color, and lightness were significant at 412.4–439.5 J/m2 and 755.9–800.0 J/m2 at α = 0.05; all indicators were significant at 363.3–486.2 J/m2 and 728.2–800.0 J/m2 at α = 0.1.
The new analytical method made it possible to determine the ranges of external effect intensity, in which the changes in the indicator were significant or insignificant.
Assessment of future climate change impact on water balance components in Central Rift Valley Lakes Basin, Ethiopia
Authors: Balcha Sisay Kebede , Awass Adane Abebe , Hulluka Taye Alemayehu , Bantider Amare , Ayele Gebiaw T. 
Published: December 2022

Abstract
This study aims to assess the impact of climate change on the water balance component of the Katar and Meki watersheds of the Central Rift Valley Lakes Basin, Ethiopia. The semi-distributed soil and water assessment tool hydrological model and multiple regional climate model outputs were used to assess climate change impacts on water balance components and stream flow. Future climate scenarios were developed under a representative concentration pathway (RCP 4.5 and 8.5) for the 2040s (2021–2050) and 2070s (2051–2080). The study found that future annual and seasonal rainfall will show increasing and decreasing trends but that they are statistically insignificant. Furthermore, future temperatures show a significant increase in the subbasins. For the applied scenarios, an increasing and decreasing trend of future rainfall and increased temperatures would decrease the water yield by 4.9–15.3% at the Katar subbasin and 6.7–7.4% at the Meki subbasin. Furthermore, annual water yields will increase in the range of 0.38–57.1% and 6.57–49.9% for the Katar and Meki subbasins, respectively. The findings of this study will help basin planners, policymakers, and water resource managers develop appropriate adaptation strategies to mitigate the negative effects of climate change in the rift-bound lake system.
Role of Non-coding RNA in the Pathogenesis of Intestinal Ischemia-
Reperfusion Injury
Authors: Zhang Jianmin , Liu Zhenzhen , Liu Yongqiang , Shi Yajing , Chen Feng , Leng Yufang 
Published: December 2022

Abstract:
Intestinal ischemia-reperfusion injury is a relatively common clinical condition
that seriously threatens the prognosis of patients; however, the exact mechanism of
intestinal ischemia-reperfusion injury has not been clarified. Recent studies have found
that noncoding RNAs, including but not limited to lncRNA, circRNA, and miRNA, play
an important role in the pathogenesis of intestinal ischemia-reperfusion. The findings cited
in this paper reveal the expression, function, and mechanism of noncoding RNAs during
intestinal ischemia-reperfusion. The mechanistic roles of noncoding RNAs in the occurrence
and development of intestinal ischemia-reperfusion are discussed, including cell
proliferation, autophagy, oxidative stress, apoptosis, oxidative stress, iron death, and
many other aspects. However, many unknown mechanisms of association between noncoding
RNAs and intestinal ischemia-reperfusion remain to be investigated.
Strategies for Improving the Photocatalytic Methane to Methanol Conversion Efficiency
Authors: Yu Dan , Zhang Hongwen , Liu Hengshan , Ma Ye , Han Bin , Feng Wenhui , Weng Bo 
Published: December 2022

Abstract:The photocatalytic conversion of methane (CH4) into methanol (CH3OH) has evoked great interest recently. In this minireview, we summarize the recent advances and current status on how to construct efficient semiconductor-based photocatalysts for enhancing the CH4 conversion efficiency and selectivity to CH3OH. This minireview firstly introduces the different radicals induced photocatalytic CH4 conversion mechanisms. Then, different strategies proposed for improving the CH4-to-CH3OH performance are highlighted with some selected typical examples, including engineering surface defects, tuning size and morphology, doping with different ions, designing heterojunctions, decorating with cocatalysts, and assisting with oxidants. Finally, we give a concise perspective on the existing challenges and specifically propose further research opportunities on maximizing the photocatalytic performance for CH4 conversion. It is anticipated that this minireview could bring more fundamental insights into the design of advanced photocatalysts toward CH4 to CH3OH conversion under solar light irradiation.
Nucleated Red Blood Cell Emergence-Time in Newborn Lambs Following
a Dose of Darbepoetin Alfa
Authors: Bahr Timothy M. , Albertine Kurt H. , Christensen Robert D. , Dahl Mar Janna , Rebentisch Andrew , Dawson Elaine , Major Emily , Foreman Hannah , Headden David , Vordos Zoë , Nabi Akbarali , Pettet Luke , Badrov Peter , Addison Connor , Christensen Daniel R. 
Published: December 2022

Background:
Nucleated red blood cells (NRBC) are very uncommon in the blood of children and adults, but small numbers are not rare in neonates on the day of birth. Elevated NRBC counts in neonates can be seen following erythropoietin dosing. Limited studies in human neonates suggest the time-interval between erythropoietin dosing and the first appearance of NRBC in the blood (the “NRBC emergence-time”) is in excess of 24 hours.

Methods:
We made serial blood counts (Sysmex veterinary analyzer) on ten newborn lambs; five were dosed with darbepoetin (10 μg/kg), and five were dosed with a vehicle-control to assess the NRBC emergence time under relatively controlled laboratory conditions.

Results:
The first appearance of NRBC was at 24 h (2757 ± 3210 NRBC/μL vs. 0/μL in controls). Peak was 48-72 h (16,758 ± 8434/μL vs. 0/μL in controls), followed by fewer at 96 hours (7823 ± 7114/μL vs. 0/μL in controls). Similarly, reticulocytes peaked at 48-72 h (113,094 ± 3210/μL vs. 10,790 ± 5449/μL in controls), with no changes in platelets or leukocytes.

Conclusions:
The NRBC emergence time in newborn lambs is similar to reports from newborn hu-mans. By extrapolation, if a neonate has a high NRBC at birth, the erythropoietic stimulus likely occurred within the interval 24 to perhaps 96+ hours prior to birth.
Characteristics of Products of Fibrinogen Origin in the Presence of Anti-
SARS-CoV-2 IgG in the Bloodstream
Authors: Rachkovska Antonina , Krenytska Daryna , Karbovskyy Vitalii , Halenova Tetiana , Raksha Nataliia , Vovk Tetiana , Savchuk Olexii , Liubenko Dmytro , Falalyeyeva Tetyana , Ostapchenko Liudmyla , Abenavoli Ludovico 
Published: December 2022

Background:
The hemostasis system has been extensively investigated in patients in
the acute phase of coronavirus disease 2019 (COVID-19). In contrast, the post-COVID syndrome
is a poorly known entity, and there is a lack of information on the mechanisms underlying the
hemostasis abnormalities in the post-COVID period.

Aim:
To analyze the potential changes in the parameters of the hemostasis system in the post-
COVID period in the plasma of donors with different titers of anti-SARS-CoV-2 IgG.

Methods:
The plasma from 160 donors who had recovered from COVID infection was used in
the study. Based on the results of the Abbott SARS-CoV-2 IgG serological assay, all donors were
divided into several groups: 5 ± 3 (n = 20); 55 ± 5 (n = 20); 65 ± 5 (n = 20); 75 ± 5 (n = 20); 85 ±
5 (n = 20); 95 ± 5 (n = 20); 125 ± 5 (n = 20); 175 ± 5 (n = 20) Index (S/C). A total of 20 healthy
individuals without anti-SARS-CoV-2 IgG constituted the control group. Key laboratory
parameters, such as fibrinogen concentrations, soluble fibrin monomer complex (SFMCs), and Ddimer,
were investigated. In addition, the qualitative composition of the fraction of SFMCs was
analyzed.

Results:
The slight increase in the concentration of fibrinogen, SFMCs, and D-dimers in some
donor groups have been found, which could cause the development of hemostasis disorders. In
the fraction of SFMCs, the increase in the number of protein fragments with a molecular weight
of less than 250 kDa and an increase in the level of proteins with a molecular weight of more than
270 kDa was revealed.

Conclusion:
The obtained results indicated the relationship between the changes in the parameters
of the hemostasis system and the titers of anti-SARS-CoV-2 IgG in donors in the post-COVID
period. It can be assumed that donors with higher titers of anti-SARS-CoV-2 IgG (>55 ± 5 Index
(S/C)) are more prone to hemostasis abnormalities in the post-COVID period since a pronounced
imbalance in the levels of SFMCs and D-dimer characterizes them. The appearance of protein
fragments of different molecular weights in the fraction of SFMC points to uncontrolled activation
of biochemical processes involving molecules of fibrinogenic origin. Additional studies are required
to elucidate the role of anti-SARS-CoV-2 IgG in the post-COVID period.
Modelling Factors Associated with Malnutrition and Anemia in Children under Five Years in Angola, Senegal, and Malawi by using a Joint Model
Authors: Khulu Chris , Ramroop Shaun , Habyarimana Faustin 
Published: December 2022

Background:
In Sub-Saharan Africa, malnutrition and anemia contribute a higher percentage to infant morbidity. Malnutrition is known as the dearth of proper nutrition in the human body and it is an important risk factor for the burden of diseases. The lack of hemoglobin and red cells in the human body is known as anemia, and it is divided into three groups. This paper aims to identify the determinants of anemia and malnutrition in Angola, Senegal and Malawi. The novelty of this study includes creating a sample that will be jointly modelled to identify determinants of anemia and malnutrition.

Methods:
This paper used 2016 information from Angola, Senegal and Malawi Demographic and Health Survey to conduct a secondary data analysis. To create a pool sample for the analysis, the Angola, Malawi and Senegal Demographic and Health Survey data were combined. The joint model under the generalized linear mixed model was employed to identify the determinants of malnourishment and anemia among children under five years in Angola, Senegal, and Malawi.

Results:
The analysis of the data was performed in SAS 9.4. The results of the covariance components indicated a positive correlation between nutritional status and anemia status. Joint generalized linear mixed model results revealed that children under five years residing with a mother that has attained a primary level of education are 2.995 times more likely to be malnourished when compared to children under five years residing with a mother that have attained a higher level of education. Children under five years residing in the rural setting of Angola, Senegal, and Malawi are 1.473 times more likely to be malnourished when compared to children under five years residing in the urban setting of Angola, Senegal and Malawi.

Conclusion:
Based on the joint generalized linear mixed model results, type of residence, sex of the child, age of the child, mother's level of education, birth interval and wealth index are the correlates of malnourishment and anemia in Angola, Senegal and Malawi. There is a greater need for partnership and collaboration among the studied countries to achieve the SGD target.
Prevalence of Chronic Kidney Disease Among Diabetes and Hypertensive Patients in a Teaching Hospital in Ekiti State, Southwest Nigeria
Authors: Akpor Oluwaseyi A. , Adeoye Abigael O. , Ibitoba Funmilayo A. , Akpor Oghenerobor B. 
Published: December 2022

Introduction:
Chronic kidney disease (CKD) is a growing public health problem associated with enormous economic burdens, reduced quality of life, and untimely deaths, predominantly in developing countries. Aims: The study determines the prevalence and risk factors for CKD among diabetes and hypertensive patients in a teaching hospital in Ekiti State.

Methods:
Descriptive and cross-sectional research designs were employed using a quantitative strategy. Two hundred (200) randomly selected participants participated in the study. Socio-demographic data, awareness, and risk factors for CKD were determined using a standardized questionnaire, while CKD prevalence was investigated with biophysical measurements and laboratory investigations. Descriptive analyses were used to answer the research questions, while inferential statistics were used to test hypotheses at a significant level of p < 0.05.

Results:
Findings revealed that 50% and 57.1% of the diabetics and hypertensives were above 60 years, 36.7% of the people with diabetes had comorbidity, while only 2% and 3.1% of diabetics and hypertensives participants had a family history of CKD. The study revealed that the respondents' level of awareness of CKD was inadequate. Major risk factors of CKD identified among the respondents were already diagnosed with diabetes and hypertension, age above 60 years (50% and 57.1%), herbal concoction (77.7% and 73.5%), and NSAID (74.5% and 78.6%). The prevalence of CKD for people with diabetes was 39.8%, while 57.1% for hypertensives. There was a significant relationship between respondents’ level of education and awareness of CKD (X2 =44.20, p=<0.001). The prevalence of CKD among the studied population was high.

Conclusion:
Efforts should be intensified by nurses and all other stakeholders on awareness and prevention programs for CKD. Furthermore, the promotion of patients’ satisfaction with the quality of healthcare services should be the goal to promote positive health outcomes.
Using the PAH in Teaching Reading to Sustain the Quality of EFL Students' Life
Authors: Du Ruofei , Shamida Arieff , Kaur Sidhu Gurnam 
Published: December 2022

Sustaining the quality of student life in any learning environment should be the priority of all educators. This situation becomes even more challenging when international EFL postgraduate students are expected to function in a learning environment where English is the medium of instruction. This study aimed to enhance their reading skills by implementing a learner-centred instructional framework referred to as the PAH (Pedagogy-Andragogy-Heutagogy) Continuum. This reading programme witnessed a significant increase in students' reading comprehension skills. Students claimed to be more confident and experienced joy and learner satisfaction through a nurturing learning environment that encouraged peeragogy and cybergogy.
Keywords: reading skills; postgraduate students; EFL; PAH Continuum

eISSN: 2398-4287 © 2022. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians/Africans/Arabians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.
DOI: https://doi.org/10.21834/ebpj.v7i22.4145