bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of experimental ulcerative colitis on the myenteric neurons in the P2X7 knockout mice
Authors: Machado Felipe Alexandre , Souza Roberta Figueiroa , Figliuolo Vanessa , Coutinho-Silva Robson , Castelucci Patricia 
Published: January 2023

Abstract
The objective was to study the distal colon myenteric plexus and enteric glial cells (EGCs) in P2X7 receptor-deficient (P2X7-/-) animals after experimental ulcerative colitis on. 2, 4, 6-trinitrobenzene sulfonic acid (TNBS) was injected into distal colon of C57BL/6 (WT) and P2X7 receptor gene-deficient (P2X7-/-, KO) animals. Distal colon tissues were analysed 24 h and 4 d after administration. Double immunofluorescence was used for analyses and histology was used for morphological analysis. Quantitative analysis demonstrated 13.9% and 7.1% decreases in the number/ganglia of P2X7 receptor-immunoreactive (ir) in the 24 h-WT/colitis group and 4 d-WT/colitis, respectively. There was no reduction in the number per ganglia of neuronal nitric oxide synthase (nNOS)-ir, choline acetyltransferase (ChAT)-ir and PGP9.5 (pan neuronal)-ir neurons in the 4 d-KO/colitis group. There was a reduction by 19.3% in the number of glial fibrillary acidic protein (GFAP, EGC)-ir in the 24 h-WT/colitis group and a 19% increase in the number of these cells in the 4 d-WT/colitis group. There were no profile area changes in neurons in the 24 h groups. In the 4 d-WT/colitis and 4 d-KO/colitis groups, there was an increase in the profile neuronal area of nNOS, ChAT and PGP9.5. Histological analysis showed hyperaemia, oedema or cellular infiltration in the 24 h-WT/colitis groups and 4 d-WT/colitis groups. The 4 d-KO/colitis groups showed no histological changes.
The Spindle Axial Time-Varying Thermal Error Compensation Method for Horizontal Boring and Milling Machine Tool Based on Edge Computing
Authors: Song Lei , Liu Kuo , Zhao Di , Zhang Song , Zhang Zewei , Wang Yongqing 
Published: January 2023

Abstract
The time-varying thermal error of Horizontal Boring and Milling Machine Tool (HBMMT) directly affects the manufacturing performance of high-end parts. The time-varying thermal error is in axial direction due to the radial symmetry of spindle box is good. The spindle axial time-varying thermal error compensation method based on edge computing was studied for reducing the effect of spindle axial time-varying thermal error of HBMMT on the consistency of machining accuracy of parts. The spindle axial time-varying thermal error model was established based on the speed and acceleration of spindle temperature change. The spindle axial time-varying error compensation value was acquired by the edge computing, and the error was compensated based on the principle of coordinate origin offset. The error fluctuation range with compensation was reduced by 87.7%, and the accuracy stability of HBMMT was greatly improved.
Reputational Costs and Information Disclosure: Evidence from eBay
Authors: Eddhir Ahmed 
Published: January 2023

Abstract
This paper investigates how behavior changes when sellers face costs for failing to fully disclose private information. In particular, sellers may face costs in future transactions if they conceal unfavorable information. However, these costs are only relevant for sellers who plan to undertake future transactions. Using data from iPhone 6 auctions on eBay, I find that sellers who face higher reputational costs tend to disclose both favorable and unfavorable information. Conversely, sellers with lower costs for partial disclosure tend to reveal primarily favorable information about their items. Sellers who plan to undertake future transactions choose to fully disclose information, ultimately maximizing profits in the long run. These results suggest that reputational mechanisms can increase sellers’ incentives to fully disclose information, thereby reducing efficiency losses from asymmetric information and improving market outcomes.
The Relationship Between Attendance of at Least Four Antenatal Care Visits and Facility Delivery
Authors: Nkeeto Bill , Yawe Bruno L. , Matovu Fred 
Published: January 2023

Abstract

Background

The current global situation is such that 340,000 women still die annually of avoidable maternal health-related complications. Recent statistics in Uganda indicate that maternal deaths among women of age 15 – 49 years are 18% translating to a maternal mortality ratio of 336 deaths per 100,000 live births. Moreover, at least 26% of live deliveries are not attended to by professional practitioners, and 27% are not delivered at a health facility. Additionally, 40% of the last Uganda Demographic and health survey did not attend at least four antenatal care visits, a minimum formerly advocated for before the introduction of the eight contact visits.

Methods

The study used a cross-sectional research design with the dataset of the most recent UDHS of 2016. A sample of 9869 most recent births for which full information of delivery and ANC was attained, was used. The multilevel logistic regression model was fitted at both bivariate and multivariate levels, as well as a random intercept model to establish latent influence within the communities/clusters. Stata 16 was used for data analysis.

Results

The results showed that 28.2% Inter class correlation relates to the latent community influence on the health-seeking behavior of mothers on whether to deliver in health facilities or otherwise. Determinants positively associated with facility delivery included at least four ANC (OR=1.59, CI=1.28 – 1.85), professionally employed partner (OR = 1.38; CI =1.09 - 1.74) use of mobile phones (OR =1.23; CI). Those negatively associated include; no education (OR = 0.41; CI = 0.19 - 0.84), unwanted pregnancy (OR=0.98; CI = 0.87 - 1.13), and partner with primary education level (OR = 0.71; CI = 0.51 - 0.99).

Conclusion

There is a need to ensure sensitization about the 8 ANC visits which the bivariate stage of this study found positively associated with facility delivery, even with limited awareness. More so, advocacy through social marketing to positively influence the latent effect and encourage contraception use or abstinence to avoid unwanted pregnancies.
The specific brain imaging alteration underlying the autistic traits in children with attention-deficit/hyperactivity disorder
Authors: Liu Juan , Liu Qian-Rong , Wu Zhao-Min , Wang Yuan , Cao Xiao-Lan , Dai Mei-Xia , Dong Chao , Liu Qiao , Zhu Jun , Chen Qiao Ru , Zhang Lin-Lin , Li Ying , Wang Yu-Feng , Liu Lu , Yang Bin-Rang 
Published: January 2023

Abstract
Object: Autistic traits (ATs) were frequently reported in children with attention-deficit/hyperactive disorder (ADHD). This study aimed to examine ATs in children with ADHD from both behavioral and neuroimaging aspects.
Method: The Autism Spectrum Screening Questionnaire was used to assess and define subjects with and without ATs. For the behavioral analyses, 67 ADHD children with ATs (ADHD+ATs), 105 ADHD children without ATs (ADHD-ATs), and 44 typically developing controls (CONs) were recruited. The resting-state functional MRI data were collected and the mean ALFF (mALFF) values were analyzed in a subsample. The ‘brain-behavior’ relationship was explored to illustrate the potential shared and distinct imaging features for ATs and ADHD symptoms.
Result:Compared to ADHD-ATs, the ADHD+ATs group showed higher ATs and hyperactivity/impulsivity. Partial correlation analysis indicated hyperactive/impulsive significantly positively correlated with all aspects of ATs in ADHD. Imaging analyses indicated that mALFF values in left middle occipital gyrus (MOG), left parietal lobe (PL)/precuneus and left middle temporal gyrus (MTG) might be specifically related to ADHD, while that of right MTG might be more closely related to ATs. Meanwhile, the altered mALFF in right PL/precuneus was correlated with both ADHD and ATs, whereas with diverse direction.
Conclusion:The co-occurrence of ATs in children with ADHD indicated different behavioral characteristics and potentially specific brain functional alterations. The assessment of ATs in children with ADHD could help us to understand the heterogeneity of ADHD, and further improve the exploration of its pathogenesis and promote clinical intervention.
A large earthquake could occur in southeastern Sumatra or Jawa， Indonesia within the next several years
Authors: Chen Xuezhong , Li Yane , Chen Lijuan 
Published: January 2023

Abstract
In this article, we focused on the region including southeastern Sumatra and Jawa,Indonisia, conducted a joint analysis of the b-value and apparent stress to investigate the stress in the crustal rock. We also examine the correlation between the variations in the rate of Earth’s rotation and the occurrence of earthquakes there by means of P-value. The results are outlined below. In the area 100km south of Jakarta, the b value decreased ~ 48% within ten years from 2009 to 2018 in and around the area. An obvious upward trend in the apparent stress started at the beginning of 2002 and ended in July 2019. From August 2019 until July 2022, the apparent stress decreased, reflecting that a stage of sub-instability or critical state could have occurred. It‘s shown that lower P-values concentrate mainly around Bengkulu, about 370km west of Jakarta, indicating a significant correlation between the occurrence of earthquakes and the Earth’s rotation there. Based on the above results, we can conclude that there could occur a strong earthquake of Mw ≥8.0 in Jawa or southeastern Sumatra, Indonesia within the future several years. This is maybe important to reduce the seismic damage there.
Behavioral Performance and Microglial Status in Mice After Moderate Dose of Proton Irradiation
Authors: Sorokina S. S. , Malkov A. E. , Rozanova O. M. , Smirnova H. N. , Shemyakov A. E. 
Published: January 2023

Abstract
The cognitive impairment is a remote effect of gamma radiation treatment of malignancies. The major part of the studies on the effect of proton irradiation (a promising alternative in the treatment of radioresistant tumors and tumors located close to critical organs) on the cognitive abilities of laboratory animals and their relation to morphological changes in the brain is rather contradictory. The aim of this study was to investigate cognitive functions and the dynamics of changes in morphological parameters of hippocampal microglial cells after proton irradiation. Two months after the cranial irradiation, 8–9-week-old male SHK mice were tested for total activity, spatial learning, as well as long- and short-term hippocampus-dependent memory. To estimate the morphological parameters of microglia, the brain slices of control and irradiated animals each with different time after proton irradiation (24 h, 7 days, 1 month) were stained for microglial marker Iba-1. No changes in behavior or deficits in short-term and long-term hippocampus-dependent memory were found, but the impairment of episodic memory was observed. A change in the morphology of hippocampal microglial cells, which is characteristic of the transition of cells to an activated state, was detected. Radiation-induced oxidative stress into the brain tissue of mice one day after exposure resulted in a slight decrease in cell density, which was restored to the control level by 30 days after exposure, probably due to the activation of proliferation. The results obtained may be promising with regard to the future use of using high doses of protons per fraction in the irradiation of tumors.
Agreement Between 4D Transesophageal Echocardiography and Multi-detector Computed Tomography in Measuring Aortic Root Dimensions and Coronary Ostia Heights
Authors: Hassan Mohamed , Abdrabou Mostafa M. , Wahba Wasseem Amin , Baghdady Yasser , Elamragy Ahmed A. 
Published: January 2023

Abstract
Purpose
Multi-detector computed tomography (MDCT) is the gold standard non-invasive tool for evaluating aortic root dimensions. We assessed the agreement between 4D TEE and MDCT-derived aortic valve annular dimensions, coronary ostia height, and minor dimensions of sinuses of Valsalva (SoV) and sinotubular junction (STJ).
Methods
In this prospective analytical study, we measured the annular area, annular perimeter, area-derived diameter, area-derived perimeter, left and right coronary ostial heights, and minor diameters of the SoV and the STJ using ECG-gated MDCT and 4D TEE. TEE measurements were calculated semi-automatically by the eSie valve software.
Results
We enrolled 43 adult patients (27 males, median age: 46 years). We found strong correlations and good agreement between the two modalities in annular dimensions (area, perimeter, area-derived diameter, and perimeter-derived diameter), left coronary ostial height, minimum STJ diameter, and minimum SOV diameters. Moderate correlations, and agreement, with relatively large differences between the 95% LOA, were demonstrated for the right coronary artery ostial height.
Conclusion
4D TEE correlates well with MDCT in measuring aortic annular dimensions, coronary ostial height, sinuses of Valsalva minor diameter, and sinotubular junction minor diameter. Whether this can affect clinical outcomes is unknown. It could replace MDCT if the latter is unavailable or contraindicated.
A numerical study on seismic risk assessment of historic masonry towers: a case study in İstanbul
Authors: Saygılı Özden 
Published: January 2023

Abstract
A probabilistic seismic hazard analysis was performed for İstanbul considering the seismotectonic structure of the region. Earthquakes that occur in seismic regions has the possibility of triggering each other to a certain extent, and this causes earthquakes to cluster in time and space. In this study, the Poisson model was preferred for probabilistic seismic hazard analysis. Conventional integration approach was adopted to calculate the hazard curves to describe the likelihood of exceeding ground motion in a particular period. This paper presents results on the impact of seismic hazard on structural performance of an existing masonry tower, by evaluating the seismic response for different levels of ground motions.
Which Treatment is Best for Adult Humerus Distal 1/3 Fractures Without Extension to the Elbow Joint?
Authors: yılmaz mehmet , ulusoy ibrahim , kıvrak aybars , iğrek servet , gürger murat 
Published: January 2023

Abstract
Adult humeral fractures that do not extend to the elbow joint can be seen with low-energy trauma in the elderly and high-energy trauma in the young. Fractures of the distal 1/3 of the humerus are treated with surgical and non-surgical methods. Our study aimed to evaluate the functional and radiological results of the distal 1/3 humerus fractures, which do not involve the joint, by comparing the conservative and surgical treatments and the surgical techniques used.
Materials and Methods
Thirty-five patients with adult distal 1/3 humeral fractures that did not extend to the joint between January 2010 and October 2014 were included in the study. The cases were evaluated retrospectively.
Results
9 of the cases were female and 26 were male. The mean age of the patients was 33,6. Articular range of motion (ROM) of cases was measured averagely at 118,8˚, and extension loss was measured at 7,14˚ averagely. The average Mayo score of cases had been measured at 87 . Mono plaque osteosynthesis has been applied to 20 of cases (Group I), double plate osteosynthesis has been applied to 11 (Group II), and conservative treatment has been applied to 4 (Group III). A statistical significant difference between Group I and Group II has not been determined regarding union time, complication, Mayo Score, Cassebaum’s rating, ROM, and extension loss. According to surgical approaches applied to patients (lateral-posterior), while a statistical difference has not been determined regarding complications, union time, and ROM, a significant difference has been determined regarding Mayo Score and extension loss. According to different determination methods; a statistical difference has not been determined regarding to complications, ROM, extension loss, Mayo Score and union time.
Discussion
We recommend surgery with a lateral approach to preserve the extensor mechanism in fractures of the distal 1/3 of the humerus.
Superelastic ferroelectric micropillar with large hysteresis and surper-durability
Authors: Li Yingwei , Chu Kangjie , Wang Xiaomei , Wu Zhijun , Peng Qi , Li Jiangyu , Chen Long-Qing , Ren Fuzeng , Sun Qingping 
Published: January 2023

Abstract
Hysteresis and durability are generally on the opposite sides of a trade-off for superelastic materials (1-10). We herein break this trade-off and report that BaTiO3 (BT) micropillars present size-dependent superelasticity and possess simultaneous large hysteresis and super-durability, sustaining up to 108 cycles without functional degradation and structural failure. The super-durability was attributed to the small stress to drive ferroelastic switching and the moderate mismatch stress between different ferroelectric variants, that are much smaller than the dislocation nucleation activation stress and the compression strength of BT pillars (11-13). These discoveries enable ferroelectric micropillars many promising applications such as microdampers, and also provide significant insight into developing superelastic materials with enhanced durability.
Determining the drilling mud window by integration of geostatistics, intelligent, and conditional programming models in an Oilfield of SW Iran
Authors: Kianoush Pooria , Mohammadi Ghodratollah , Hosseini Seyed Aliakbar , Khah Nasser Keshavarz Faraj , Afzal Peyman 
Published: January 2023

Abstract

Accurate knowledge of pore and fracture pressures is essential for drilling wells safely with the desired mud weight (MW). Overpressure occurs when the pore pressure is higher than the normal hydrostatic pressure. There is a challenge regarding the pressure studies domain in an oilfield in SW Iran, where lack of geo-mechanical data limits exact mud window calculation. Also, the reservoir generally consists of carbonate rocks and contains no shale interbeds, so mechanical stratigraphy based on Gamma ray could not be applied. This study is to provide safe drilling considering MW to prevent the flow or loss in the vicinity of the new wells in the studied field. In this research the formation pressures and mud window models are determined by combining geostatistical, intelligent, and conditional programming models and compared with real data. The conditional programming was also used to correct small out-of-range data. The highest correlation between the final effective pressure and velocity cube was observed in lower Fahliyan Formation with 0.86 and Ilam with 0.71.The modeled MW difference ranged between 2.5 and 30 PCF. Also, the maximum modeled MW is 150 PCF in the upper Fahliyan Formation. Heavy mud of more than 130 PCF is suggested for drilling the Khalij member and continues to the end of stratigraphy column. Best observed correlation comparing the drilled and modeled MW, especially achieved in the Fahliyan reservoir Formation with more than 100 PCF and the Ilam Formation with 80-100 PCF. Finally, 3D formation pressures is presented and recommended for further safe drillings.
The Effects of Tilt Angle Filter on Noise Cancelation and Structural Edges Detection in Gas and Oil Source in Gravitational Potential Field of Qeshm Island SE Iran
Authors: Hosseini Seyed Aliakbar , Khah Nasser Keshavarz Faraj , Kianoush Pooria , Arjomandi Mojtaba , Ebrahimabadi Arash 
Published: January 2023

Abstract
One of the most critical issues in describing gravitational maps is separating the anomalies related to shallow sources from the deep ones. In this study, every kilometer of assessing gravity in a very regular network is done from the shallow part of the west of Qeshm Island to Hormoz and its north coast from Sarkhoun to Latidan in SE Iran. The range of gravitational Bouguer changes is from − 297 to-330 miligal (mGal), which after modeling and determining geometrical parameters, It was found that five negative anomalies came from salt penetration in this region. On the Bouguer anomaly maps, profound effects were seen as light and linear, called regional effects. The residual gravity was computed by removing gravitational effects related to deep sources from measured gravitational data. Regional anomalies have a low spatial frequency and long wavelength, while residual anomalies are related to under-surface potentials and have a high spatial frequency and short wavelength. By comparing the result after employing the tilt angle filter on different gravitational field maps during the tilt angle computation, the fundamental part of the hyperbolic tangent function was used instead of using the tangent function. Results of the boundary and edges of the subsurface masses are better than regional filters, so anomalies intensely were highlighted. Therefore, a hyperbolic tilt angle can reduce the sensitivity to existing noises and induction ones. This paper studied the effect of the local phase filter of the gravity tilt angle on the artificial model from coding in MATLAB software.
Focused single-cell analysis with principal feature analysis, mutual information, and machine learning reveals cell type signatures
Authors: Breitenbach Tim , Caliskan Aylin , Caliskan Deniz , Rasbach Lauritz , Yu Weimeng , Dandekar Thomas 
Published: January 2023

Abstract
Our single-cell analysis pipeline identifies a set of key genes whose expression describes the difference between cell types and consists of
(i) R packages Seurat and DoubletFinder preprocess single cell data according to quality. Next, a custom-made python script randomizes obtained data, generating random sets for comparison.
(ii) Principal feature analysis (PFA) identifies genes contributing to characteristic differences in cell types, represented by corresponding labels, removing redundant genes that are functions of others, leaving only genes that are arguments of such functions.
(iii) Genes associated with predicting the labels of the cells are selected. For further reduction, selected genes are ranked by the mutual information that the expression of these genes shares with the labels representing the cell types.
(iv) Importantly, selected genes are validated by a machine learning framework where the prediction accuracy on all genes vs. the selected genes is tested.
(v) If desired, mutual information ranking balances the number of selected genes and information content for predicting the cell types. Results from different single-cell data include: comparisons of adipocytes and adipose stem and progenitor cells (ASPCs), adipocytes and mesothelium, and endothelial cells and mesothelium, as well as fibroblast and macrophage. In each, only about ten out of more than 30000 genes are identified carrying the relevant information classifying the single cells for distinguishable cell types. Our code is provided in a GitHub repository at … ( link will be added after acceptance).
What Do I Do to Avoid Sexually Transmitted Diseases? A Scale Development Study: Behavioral Scale for Protection from Sexually Transmitted Diseases
Authors: Kılavuz PhD Student , Yiğit Assistant Professor Feride 
Published: January 2023

Abstract
The authors' aim is to develop and confirm a reliable and valid measurement tool that can measure women's behavior to prevent sexually transmitted diseases. The study data were collected from adult women aged 18-47 years (n= 505). Exploratory Factor Analysis (EFA) was applied to the STD scale consisting of 44 items. According to the results of EFA, 21 items were defined in the scale. The KMO value of the scale is 90.6%. In the study, the varimax rotation method was used to bring the factors together with the related items. As a result of varimax rotation, two factors with eigenvalues greater than 1 were found in the scale. The overall Cronbach's Alpha coefficient of the scale has been calculated as 0.911, 0.941 for the first sub-dimension and 0.889 for the second sub-dimension. The validity and reliability of this study has been proven according to the results of explanatory factor analysis (EFA) and confirmatory factor analysis (CFA).