bluuebunny/crossref_metadata_2025_split huggingface dataset:
PANDORA Project for the study of photonuclear reactions below $$A=60$$
Authors: Tamii A. , Pellegri L. , Söderström P.-A. , Allard D. , Goriely S. , Inakura T. , Khan E. , Kido E. , Kimura M. , Litvinova E. , Nagataki S. , Neumann-Cosel P. von , Pietralla N. , Shimizu N. , Tsoneva N. , Utsuno Y. , Adachi S. , Adsley P. , Bahini A. , Balabanski D. , Baret B. , Bekker J. A. C. , Binda S. D. , Boicu E. , Bracco A. , Brandherm I. , Brezeanu M. , Brummer J. W. , Camera F. , Crespi F. C. L. , Dalal R. , Donaldson L. M. , Fujikawa Y. , Furuno T. , Haoning H. , Higuchi R. , Honda Y. , Gavrilescu A. , Inoue A. , Isaak J. , Jivan H. , Jones P. , Jongile S. , Just O. , Kawabata T. , Khumalo T. , Kiener J. , Kleemann J. , Kobayashi N. , Koshio Y. , Kuşoğlu A. , Li K. C. W. , Malatji K. L. , Molaeng R. E. , Motoki H. , Murata M. , Netshiya A. A. , Neveling R. , Niina R. , Okamoto S. , Ota S. , Papst O. , Parizot E. , Petruse T. , Reen M. S. , Ring P. , Sakanashi K. , Sideras-Haddad E. , Siem S. , Spall M. , Suda T. , Sudo T. , Taniguchi Y. , Tatischeff V. , Utsunomiya H. , Wang H. , Werner V. , Wibowo H. , Wiedeking M. , Wieland O. , Xu Y. , Yang Z. H. ,   PANDORA Collaboration
Published: September 2023

AbstractPhotonuclear reactions of light nuclei below a mass of $$A=60$$

A
=
60

are planned to be studied experimentally and theoretically with the PANDORA (Photo-Absorption of Nuclei and Decay Observation for Reactions in Astrophysics) project. Two experimental methods, virtual photon excitation by proton scattering and real photo absorption by a high-brilliance $$\gamma $$
γ
-ray beam produced by laser Compton scattering, will be applied to measure the photoabsorption cross sections and decay branching ratio of each decay channel as a function of the photon energy. Several nuclear models, e.g. anti-symmetrized molecular dynamics, mean-field and beyond-mean-field models, a large-scale shell model, and ab initio models, will be employed to predict the photonuclear reactions. The uncertainty in the model predictions will be evaluated based on the discrepancies between the model predictions and experimental data. The data and predictions will be implemented in the general reaction calculation code, . The results will be applied to the simulation of the photo-disintegration process of ultra-high-energy cosmic rays in inter-galactic propagation.
Mass spectra of hidden heavy-flavor tetraquarks with two and four heavy quarks
Authors: Yan Ting-Qi , Zhang Wen-Xuan , Jia Duojie 
Published: September 2023

AbstractInspired by the observation of theX(6900) by LHCb and theX(6600) (with mass$$6552\pm 10\pm 12$$6552±10±12 MeV) recently by CMS and ATLAS experiments of the LHC in the di-$$J/\varPsi $$J/Ψinvariant mass spectrum, we systemically study masses of all ground-state configurations of the hidden heavy-flavor tetraquarks$$q_{1}Q_{2}{\bar{q}}_{3}{\bar{Q}}_{4}$$q1Q2q¯3Q¯4and$$Q_{1}Q_{2}{\bar{Q}}_{3}{\bar{Q}}_{4}$$Q1Q2Q¯3Q¯4$$(Q=c,b$$(Q=c,b;$$q=u,d,s)$$q=u,d,s)containing two and four heavy quarks in the MIT bag model with chromomagnetic interaction and enhanced binding energy. Considering color-spin mixing due to chromomagnetic interaction, our mass computation indicates that the observedX(6600) is likely to be the$$0^{++}$$0++ground states of hidden-charm tetraquark$$cc{\bar{c}}{\bar{c}}$$ccc¯c¯with computed masses 6572 MeV, which has a$$0^{++}$$0++color partner around 6469 MeV. The fully bottom system of tetraquark$$bb{\bar{b}}{\bar{b}}$$bbb¯b¯has masses of 19685 MeV and 19717 MeV for the$$0^{++}$$0++ground states. Further calculation of the tetraquark systems$$sc{\bar{s}}{\bar{c}}$$scs¯c¯,$$sb{\bar{s}}{\bar{b}}$$sbs¯b¯,$$cb{\bar{c}}{\bar{b}}$$cbc¯b¯,$$nc{\bar{n}}{\bar{c}}$$ncn¯c¯and$$nb{\bar{n}}{\bar{b}}$$nbn¯b¯shows that$$Z_{c}(4200)$$Zc(4200)is a$$1^{+-}$$1+-state of tetraquark$$nc{\bar{n}}{\bar{c}}$$ncn¯c¯andZ(4020) is a$$1^{+-}$$1+-state of tetraquark$$nc{\bar{n}}{\bar{c}}$$ncn¯c¯with a mass of 4079 MeV. All of these tetraquarks are above their lowest thresholds of two mesons and unstable against the strong decays.
Constraining the top-quark mass within the global MSHT PDF fit
Authors: Cridge Thomas , Lim Matthew A. 
Published: September 2023

AbstractWe examine the ability of experimental measurements of top-quark pair production to constrain both the top-quark mass and the strong coupling within the global MSHT parton distribution function (PDF) fit. Specifically, we consider ATLAS and CMS measurements of differential distributions taken at a centre-of-mass energy of 8 TeV, as well as $$ t\bar{t}$$

t

t

¯

total cross section data taken at a variety of experiments, and compare to theoretical predictions including next-to-next-to-leading order corrections. We find that supplementing the global fit with this additional information results in relatively strong constraints on the top-quark mass, and is also able to bound the strong coupling in a limited fashion. Our final result is $$m_t=173.0\pm 0.6~\textrm{GeV}$$

m
t

=
173.0
±
0.6

GeV

and is compatible with the world average pole mass extracted from cross section measurements of $$172.5\pm 0.7~\textrm{GeV}$$

172.5
±
0.7

GeV

by the Particle Data Group. We also study the effect of different top-quark masses on the gluon parton distribution function, finding changes at high x which nonetheless lie within the large PDF uncertainties in this region.
A realistic coalescence model for deuteron production
Authors: Mahlein Maximilian , Barioglio Luca , Bellini Francesca , Fabbietti Laura , Pinto Chiara , Singh Bhawani , Tripathy Sushanta 
Published: September 2023

AbstractA microscopic understanding of (anti)deuteron production in hadron–hadron collisions is the subject of many experimental and theoretical efforts in nuclear physics. This topic is also very relevant for astrophysics, since the rare production of antinuclei in our Universe could be a doorway to discover new physics. In this work, we describe a new coalescence afterburner for event generators based on the Wigner function formalism and we apply it to the (anti)deuteron case, taking into account a realistic particle emitting source. The model performance is validated using the EPOS and PYTHIA event generators applied to proton–proton collisions at the centre-of-mass energy $$\sqrt{s}= 13$$

s

=
13

TeV, triggered for high multiplicity events, and the experimental data measured by ALICE in the same collision system. The model relies on the direct measurement of the particle emitting source carried out by means of nucleon–nucleon femtoscopic correlations in the same collision system and energy. The resulting model is used to predict deuteron differential spectra assuming different deuteron wavefunctions within the Wigner function formalism. The predicted deuteron spectra show a clear sensitivity to the choice of the deuteron wavefunction. The Argonne $$v_{18}$$

v
18

wavefunction provides the best description of the experimental data. This model can now be used to study the production of (anti)deuterons over a wide range of collision energies and be extended to heavier nuclei.
Combined analysis on nature of X(3960), $$\chi _{c0}(3930)$$, and $$X_0(4140)$$
Authors: Ding Zuo-ming , He Jun 
Published: September 2023

AbstractIn this work, a study of the $$D_s{\bar{D}}_s$$

D
s

D

¯

s

interaction and its couplings to the channels $$D{\bar{D}}$$

D

D

¯

and $$J/\psi \phi $$

J
/
ψ
ϕ

is performed in a quasipotential Bethe–Salpeter equation approach. The $$D_s^+{D}_s^-$$

D
s
+

D
s
-

and $$D^+{D}^-$$

D
+

D

-

invariant mass spectra in three-body B decays are investigated in order to understand the origin of X(3960), $$\chi _{c0}(3930)$$

χ

c
0

(
3930
)

, and $$X_0(4140)$$

X
0

(
4140
)

structures reported at LHCb. With the help of effective Lagrangians, the potential kernel can be constructed with meson exchanges, from which the scattering amplitudes can be obtained. By inserting it into the three-body decay processes, the invariant mass spectra can be calculated with an additional Breit–Wigner resonance introduced. The $$D_s^+{D}_s^-$$

D
s
+

D
s
-

invariant mass spectrum in the decay process $$B^+\rightarrow D^+_sD^-_sK^+$$

B
+

→

D
s
+

D
s
-

K
+

is well reproduced, and the X(3960) structure can be explained as a molecular state from the $$D_s{\bar{D}}_s$$

D
s

D

¯

s

interaction. The state also exhibits as a peak in the $$D^+{D}^-$$

D
+

D

-

invariant mass spectrum in the decay $$B^+\rightarrow D^+D^-K^+$$

B
+

→

D
+

D
-

K
+

, however, it is too narrow to reproduce the experimental structure around 3930 MeV. The dip around 4140 MeV in the $$D_s^+{D}_s^-$$

D
s
+

D
s
-

invariant mass spectrum can be reproduced by the additional resonance with interference effect. However, a small bump instead of a dip is produced from the $$D_s{\bar{D}}_s-J/\psi \phi $$

D
s

D

¯

s

-
J
/
ψ
ϕ

coupled-channel effect, which suggests that the $$X_0(4140)$$

X
0

(
4140
)

cannot be interpreted as the $$D_s{\bar{D}}_s-J/\psi \phi $$

D
s

D

¯

s

-
J
/
ψ
ϕ

coupling in the current model.
Colliding cratons: linking the Variscan Orogeny in West Africa and North America
Authors: Villeneuve Michel , Gärtner Andreas , Mueller Paul A. , Guillou Omar , Linnemann Ulf 
Published: September 2023

Abstract

The Variscan Orogen was formed during the closure of the Rheic Ocean and the final collision between the North American and West African cratons in the Late Paleozoic. This collision led to the multistage building of the Mauritanide Belt to the east of the Variscan suture and to the building of the well-known Appalachian Belt to the west. Both led to opposite vergences in this part of the Variscan belt. The earliest records of the main collision episode begin at ∼360 Ma and end about 250 myr ago, while a late extensional phase lasted until ∼190 Ma. Three distinct stages are recognized in West Africa. The first stage (
c.
350–300 Ma) records the indentation of the Reguibat Shield into the central Appalachian margin of Laurentia. This indentation led to thrusting of the Souttoufide and Akjoujt ‘nappes’ onto the Reguibat Shield, to southward motion of the Senegalese block (SB), and to strike-slip motion in the Appalachians. The motion of the SB to the south is coeval with: (1) folding of the northern part of the Bové Basin, (2) north–south sinistral strike-slip motions in the central Mauritanides, and (3) the end of sedimentation in the Bové and Taoudeni Basins by the Late Devonian. The second stage (
c.
300–250 Ma) involves the eastward motion of the Western Thrust Block (WTB) against the SB and, likely, some of the westward thrusts in the Appalachians. This second ‘Variscan’ event includes: (1) closure of parts of the lower Diourbel Carboniferous basin, which is now concealed beneath the Senegalo-Mauritanian Basin, (2) thrusting to the east of the Simenti Group over the Koulountou Group in the Bassaride Belt, (3) thrusting to the east of the Wa-Wa Group, (4) thrusting of the Mauritanide Belt onto the Taoudeni Basin in the central Mauritanide Belt, and finally (5) thrusting of the Agualilet Group over the Akjoujt nappes and eastward motion of the western units over the Dhloat Ensour (Late Ordovician to early Devonian) autochthonous unit in the Souttoufides. West of the supposed ‘Variscan’ suture, Appalachian thrusting affected parts of Appalachian Belt. The third stage (
c.
250 to 190 Ma) began with the opening of Triassic rift basins in the Senegalo-Mauritanian basin and also in the north of Florida. As numerous previous correlations across the Variscan system do not include the West African part, our sythesis is intended to enhance these correlations.
VISTA Expression on Cancer-Associated Endothelium Selectively Prevents T-cell Extravasation
Authors: Luk Sietse J. , Schoppmeyer Rouven , Ijsselsteijn Marieke E. , Somarakis Antonios , Acem Ibtissam , Remst Dennis F.G. , Cox Daan T. , van Bergen Cornelis A.M. , Briaire-de Bruijn Inge , Grönloh Max L.B. , van der Meer Werner J. , Hawinkels Lukas J.A.C. , Koning Roman I. , Bos Erik , Bovée Judith V.M.G. , de Miranda Noel F.C.C. , Szuhai Karoly , van Buul Jaap D. , Falkenburg J.H. Frederik , Heemskerk Mirjam H.M. 
Published: September 2023

Abstract
Cancers evade T-cell immunity by several mechanisms such as secretion of anti-inflammatory cytokines, down regulation of antigen presentation machinery, upregulation of immune checkpoint molecules, and exclusion of T cells from tumor tissues. The distribution and function of immune checkpoint molecules on tumor cells and tumor-infiltrating leukocytes is well established, but less is known about their impact on intratumoral endothelial cells. Here, we demonstrated that V-domain Ig suppressor of T-cell activation (VISTA), a PD-L1 homolog, was highly expressed on endothelial cells in synovial sarcoma, subsets of different carcinomas, and immune-privileged tissues. We created an ex vivo model of the human vasculature and demonstrated that expression of VISTA on endothelial cells selectively prevented T-cell transmigration over endothelial layers under physiologic flow conditions, whereas it does not affect migration of other immune cell types. Furthermore, endothelial VISTA correlated with reduced infiltration of T cells and poor prognosis in metastatic synovial sarcoma. In endothelial cells, we detected VISTA on the plasma membrane and in recycling endosomes, and its expression was upregulated by cancer cell–secreted factors in a VEGF-A–dependent manner. Our study reveals that endothelial VISTA is upregulated by cancer-secreted factors and that it regulates T-cell accessibility to cancer and healthy tissues. This newly identified mechanism should be considered when using immunotherapeutic approaches aimed at unleashing T cell–mediated cancer immunity.
HER2-Selective and Reversible Tyrosine Kinase Inhibitor Tucatinib Potentiates the Activity of T-DM1 in Preclinical Models of HER2-positive Breast Cancer
Authors: Olson Devra , Taylor Janelle , Willis Kelsi , Hensley Kelly , Allred Sean , Zaval Margo , Farr Lauren , Thurman Robert , Jain Nishi , Hein Renee , Ulrich Michelle , Peterson Scott , Kulukian Anita 
Published: September 2023

The oncogenic receptor HER2 is overexpressed in many cancers, including up to 20% of breast cancers. Despite the availability of HER2-targeted treatments, patients’ disease often progresses during therapy, underscoring the need for novel treatment strategies. The addition of tucatinib, a reversible, highly selective HER2 tyrosine kinase inhibitor (TKI), to treatment with trastuzumab and capecitabine significantly improved survival outcomes of patients with HER2-positive metastatic breast cancer, including those with active brain metastases. We rationalized that combining tucatinib with other HER2-targeting agents with complementary mechanisms of action would further increase efficacy against tumors. We characterized the activity of tucatinib with the antibody–drug conjugate T-DM1 in preclinical models of breast cancer, including HER2-positive breast cancer cells and patient-derived xenograft (PDX) models. Mechanistic details on tucatinib activity were obtained in internalization and catabolism studies. In combination, tucatinib and T-DM1 showed an enhanced, often synergistic, cytotoxic response and demonstrated improved antitumor activity in vivo, including in PDX models refractory to T-DM1 single-agent activity. Mechanistically, tucatinib mediated an increase in inactive HER2 molecules at the cell surface through inhibition of HER2 ubiquitination, resulting in increased internalization and catabolism of T-DM1. The combination was correlated with enhanced HER2 pathway inhibition, decreased proliferation, and increased apoptosis. In a xenograft model of brain metastasis, tucatinib penetrated intracranial tumor tissues, inhibiting tumor growth and improving survival. These results suggest that tucatinib may be the optimal TKI partner for HER2-targeted therapies and support clinical studies of its combination with T-DM1, including in patients with brain metastases.

Significance:
The preclinical findings in breast cancer models presented here demonstrate that combining tucatinib with T-DM1 enhances the antitumor activity of either agent alone, supporting clinical studies of the combination in HER2-positive breast cancer, including in patients with brain metastases, which remains an important unmet medical need.
Estados recusados: o efeito do culturalismo em nações com histórico de colonização
Authors: Zocca Ricardo , Martins Moisés de Lemos 
Published: September 2023

Este estudo analisa a formação de Estados de minorias com Deleuze & Guattari (1997), o efeito do culturalismo em nações com histórico de colonização proposto por Souza (2019), além da influência que o sistema econômico tem nesse processo com Mandel (1998), atuando também como agente de pureza de Bauman (1998). A culminação desse processo divide os países e as populações em duas castas, a elite europeizada e o populacho, num movimento que se espiraliza e se retroalimenta. A elite se enxerga como distante da população e ocupa os principais cargos de informação no país, alastrando o culturalismo para todas as camadas da população.
Cildo Meireles e a reforma do zero da economia
Authors: Hermann Victor 
Published: September 2023

O sistema monetário internacional deve passar por transformações radicais em virtude da concorrência de moedas digitais e da emergência de uma nova ordem multipolar. Em busca de propor um conceito alternativo de dinheiro, neste artigo revisitaremos as obras de Cildo Meireles que versam sobre o dinheiro, especialmente Zero Dólar (1978-1984), Zero Cruzeiro (1974) e Zero Real (2013), todas pertencentes ao projeto Inserções em circuitos antropológicos. O artista propõe uma reforma “do zero” da economia, em que são questionadas as relações entre moeda e matéria, entre confiança e reputação, entre criação e circulação de valor. Trata-se de uma utopia das trocas monetárias, irredutível à tirania financeira da especulação e do endividamento.
Gender bias in funding evaluation: A randomized
experiment
Authors: Cruz-Castro Laura , Sanz-Menéndez Luis 
Published: September 2023

Abstract
Gender differences in research funding exist, but bias evidence is elusive and findings are contradictory. Bias has multiple dimensions, but in evaluation processes, bias would be the outcome of the reviewers’ assessment. Evidence in observational approaches is often based either on outcome distributions or on modeling bias as the residual. Causal claims are usually mixed with simple statistical associations. In this paper we use an experimental design to measure the effects of a cause: the effect of the gender of the principal investigator (PI) on the score of a research funding application (treatment). We embedded a hypothetical research application description in a field experiment. The subjects were the reviewers selected by a funding agency, and the experiment was implemented simultaneously with the funding call’s peer review assessment. We manipulated the application item that described the gender of the PI, with two designations: female PI and male PI. Treatment was randomly allocated with block assignment, and the response rate was 100% of the population, avoiding problems of biased estimates in pooled data. Contrary to some research, we find no evidence that male or female PIs received significantly different scores, nor any evidence of same-gender preferences of reviewers regarding the applicants’ gender.
Evaluation of Long-Term Nutrition Outcomes After Duodenal Switch: A Systematic Review and Meta-Analysis
Authors: Nakanishi Hayato , Abi Mosleh Kamal , AL-Kordi Mohammad , Marrero Katie , Kermansaravi Mohammad , Davis S. Scott , Clapp Benjamin , Ghanem Omar M. 
Published: September 2023

Background Biliopancreatic diversion with duodenal switch (BPD-DS) is the most effective and durable metabolic and bariatric surgery to achieve a target weight loss. However, many surgeons are hesitant to adopt BPD-DS due to a lack of training, technical complexity, and long-term nutrition deficiencies. This meta-analysis aimed to investigate long-term nutrition outcomes after primary BPD-DS in the management of obesity. Methods Cochrane, Embase, PubMed, Scopus, and Web of Science were searched for articles from their inception to February 2023 by 2 independent reviewers using the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) system. The review was registered prospectively with PROSPERO (CRD42023391316). Results From 834 studies screened, 8 studies met the eligibility criteria, with a total of 3443 patients with obesity undergoing primary BPD-DS. At long-term follow-up (≥5 years), 25.4% of patients had vitamin A deficiency (95% CI: -.012, .520, I2 = 94%), and 57.3% had vitamin D deficiency (95% CI: .059, 1.086, I2 = 86%). Calcium deficiency was observed in 125 patients (22.2%, 95% CI: .061, .383, I2 = 97%), and 69.7% had an abnormal parathyroid hormone level (95% CI: .548, .847, I2 = 78%). Ferritin level was abnormal in 30 patients (29.0%, 95% CI: .099, .481, I2 = 79%). Conclusions Despite displaying comparable nutrition-related outcomes to mid-term follow-up, our study demonstrated that BPD-DS could result in a high level of long-term nutrition deficiency after BPD-DS for selected patients. However, further randomized controlled studies with standardized supplementation regimens and improvement in compliance are necessary to evaluate and prevent long-term nutritional deficiencies after BPD-DS.
Food Price Dynamics During the Pandemic
Authors: Sekhar C. S. C , Thapa Namrata 
Published: September 2023

Coronavirus disease 2019 (COVID-19) posed a serious challenge to food production and distribution worldwide. There were major disruptions in supply chains due to mobility restrictions and a slump in demand due to the loss of livelihoods and incomes. What effect do these offsetting movements have on prices? Which commodities experienced price increases/slumps? Were these localised or widespread across regions? What is the relative contribution of sub-groups to the overall trends? We delve into these issues using wholesale and retail price data to understand the price dynamics in India during COVID-19, using the previous four years as the reference point. The analysis revealed that the retail margins were consistently higher in 2020–2021 indicating the persistence of local shortages for all commodities. Owing to government support through procurement and distribution, the effect on cereals’ prices was minimal. Perishables like vegetables and meat/fish marketed in raw form through informal/petty trade networks, faced maximum erratic behaviour, while milk, marketed in processed form by organised intermediaries, experienced a moderate impact on prices. Fruits, a perishable but with high-income elasticity of demand, witnessed muted prices possibly due to income erosion. Pulses and oils/fats, imported in large quantum, saw a sharp price increase due to local supply bottlenecks combined with international trade disruption. JEL Codes: E31, Q11