bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mercury Exposure in Birds of Prey from Norway: Relation to Stable Carbon and Nitrogen Isotope Signatures in Body Feathers
Authors: Gómez-Ramírez Pilar , Bustnes Jan Ove , Eulaers Igor , Johnsen Trond Vidar , Lepoint Giles , Pérez-García Juan Manuel , García-Fernández Antonio Juan , Espín Silvia , Jaspers Veerle Leontina Bernard 
Published: June 2023

AbstractMercury (Hg) and stable carbon and nitrogen isotope ratios were analysed in body feathers from nestlings of white-tailed eagles (Haliaeetus albicilla) (WTE; n = 13) and Northern goshawks (Accipiter gentilis) (NG; n = 8) and in red blood cells (RBC) from NG (n = 11) from Norway. According to linear mixed model, species factor was significant in explaining the Hg concentration in feathers (LMM; p < 0.001, estimate (WTE) = 2.51, 95% CI = 1.26, 3.76), with concentrations higher in WTE (3.01 ± 1.34 µg g−1 dry weight) than in NG (0.51 ± 0.34 µg g−1 dry weight). This difference and the isotopic patterns for each species, likely reflect their diet, as WTE predominantly feed on a marine and higher trophic-chain diet compared to the terrestrial NG. In addition, Hg concentrations in RBCs of NG nestlings were positively correlated with feather Hg concentrations (Rho = 0.77, p = 0.03), supporting the potential usefulness of nestling body feathers to biomonitor and estimate Hg exposure. Hg levels in both species were generally below the commonly applied toxicity threshold of 5 µg g−1 in feathers, although exceeded in two WTE (6.08 and 5.19 µg g−1 dry weight).
Evaluating digital work instructions with augmented reality versus paper-based documents for manual, object-specific repair tasks in a case study with experienced workers
Authors: Eversberg Leon , Lambrecht Jens 
Published: June 2023

AbstractManual repair tasks in the industry of maintenance, repair, and overhaul require experience and object-specific information. Today, many of these repair tasks are still performed and documented with inefficient paper documents. Cognitive assistance systems have the potential to reduce costs, errors, and mental workload by providing all required information digitally. In this case study, we present an assistance system for object-specific repair tasks for turbine blades. The assistance system provides digital work instructions and uses augmented reality to display spatial information. In a user study with ten experienced metalworkers performing a familiar repair task, we compare time to task completion, subjective workload, and system usability of the new assistance system to their established paper-based workflow. All participants stated that they preferred the assistance system over the paper documents. The results of the study show that the manual repair task can be completed 21% faster and with a 26% lower perceived workload using the assistance system.
Angle ranks of abelian varieties
Authors: Dupuy Taylor , Kedlaya Kiran S. , Zureick-Brown David 
Published: June 2023

AbstractUsing the formalism of Newton hyperplane arrangements, we resolve the open questions regarding angle rank left over from work of the first two authors with Roe and Vincent. As a consequence we end up generalizing theorems of Lenstra–Zarhin and Tankeev proving several new cases of the Tate conjecture for abelian varieties over finite fields. We also obtain an effective version of a recent theorem of Zarhin bounding the heights of coefficients in multiplicative relations among Frobenius eigenvalues.
Reconstruction of Inferior Vena Cava by Autologous Great Saphenous Vein Grafts in Liver Surgery
Authors: Feng Xi , Wu Kan , Yang XianWei , Qiu HaiZhou , Wei YongGang , Li Bo , Wang Wentao , Huang Bin 
Published: June 2023

AbstractBackgroundTo secure surgical margin for hepatic lesion with involvement of the inferior vena cava (IVC), combined radical liver resection and IVC replacement are required. A novel method of replacing IVC by newly customized autologous great saphenous vein (GSV) grafts was introduced by this study. This study aimed at reporting the feasibility and outcome of this novel technique.MethodsFrom January 2014 to January 2021, all consecutive patients who underwent concomitant hepatectomy and IVC replacement by autogenous GSV graft were enrolled in this study. Technical insights, intraoperative details, demographic data, postoperative complication, graft patency and survival data were collected and analyzed.ResultsConcomitant hepatectomy/autotransplantation (ERAT) with IVC replacement by autogenous GSV graft was successful in 47 patients and there was no 30‐day mortality. There were 8 out of the 47 patients whose retrohepatic venae cavae were completely invaded by the lesion and their reconstructed IVCs were totally made from GSV grafts. The other 39 patients whose IVCs were partially invaded had their IVCs reconstructed by both the unaffected part of the IVC wall and newly customized GSV graft. Postoperative complications classified as Clavien‐Dindo grade II, III A and III B were observed in 10, 7 and 3 patients, respectively. The median follow‐up months were 35 months (29–80 months). No patient developed thrombosis of the graft and 100% patency of the IVC was observed throughout the study.ConclusionIn selected patients, hepatectomy/ERAT with IVC replacement by autogenous GSV graft is safe and feasible. The newly customized autologous GVS graft was ideal for reconstruction of the IVC in liver surgery.
Synthetic Versus Biological Mesh in Ventral Hernia Repair and Abdominal Wall Reconstruction: A Systematic Review and Recommendations from Evidence‐Based Medicine
Authors: Shi Hekai , Wang Rui , Dong Wenpei , Yang Dongchao , Song Heng , Gu Yan 
Published: June 2023

AbstractAimTo compare the efficacy and safety of synthetic and biological meshes in ventral hernia repair (VHR) and abdominal wall reconstruction (AWR).MethodsWe screened all clinical trials that reported the application of synthetic and biological meshes in VHR and AWR using Medline, Web of Science, and Embase (Ovid). Only comparative studies with similar baselines such as age, sex, body mass index, degree of wound contamination, and hernia defects between the intervention and control groups were included. Effect sizes with 95% confidence were pooled using a random‐ or fixed‐effects model based on the size of heterogeneity. A sensitivity analysis was performed to test the stability of the results.ResultsTen studies with 1305 participants were included. Biological meshes were associated with significantly higher recurrence rate (OR, 2.09; 95% CI 1.42–3.08; I2 = 50%), surgical site infection (OR, 1.47; 95% CI 1.10–1.97; I2 = 30%), higher re‐admission rate (OR, 1.51; 95% CI 1.05–2.17; I2 = 50%), and longer length of hospital stay (SMD, 0.37; 95% CI 0.10–0.65; I2 = 72%). Similar surgical site occurrence, re‐operation rate, and mesh explantation rate were observed among biological and synthetic meshes. Biological meshes have no difference in recurrence rate as compared to synthetic meshes, between the clean‐contaminated, and contamination‐infected fields (OR, 1.41; 95% CI 0.41–4.87 vs 3.00; 95% CI 1.07–8.46; P = 0.36).ConclusionSynthetic meshes are a safe alternative to biological meshes for VHR and AWR. Considering the high cost of biological meshes, synthetic meshes are more appropriate for the VHR and AWR.
The mitotic spindle-related seven-gene predicts the prognosis and immune microenvironment of lung adenocarcinoma
Authors: Shen Ruxin , Li Zhaoshui , Wu Xiaoting 
Published: June 2023

Abstract
Purpose
Abnormalities in the mitotic spindle have been linked to a variety of cancers. Data on their role in the onset, progression, and treatment of lung adenocarcinoma (LUAD) need to be explored.

Methods
The data were retrieved from The Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), and Molecular Signatures Database (MSigDB), for the training cohort, external validation cohort, and the hallmark mitotic spindle gene set, respectively. Mitotic spindle genes linked to LUAD prognosis were identified and intersected with differentially expressed up-regulated genes in the training cohort. Nomogram prediction models were built based on least absolute shrinkage and selection operator (LASSO) regression, univariate cox, and multivariate cox analyses. The seven-gene immunological score was examined, as well as the correlation of immune checkpoints. The DLGAP5 and KIF15 expression in BEAS-2B, A549, H1299, H1975, and PC-9 cell lines was validated with western blot (WB).

Results
A total of 965 differentially expressed up-regulated genes in the training cohort intersected with 51 mitotic spindle genes associated with LUAD prognosis. Finally, the seven-gene risk score was determined and integrated with clinical characteristics to construct the nomogram model. Immune cell correlation analysis revealed a negative correlation between seven-gene expression with B cell, endothelial cell (excluding LMNB1), and T cell CD8 + (p < 0.05). However, the seven-gene expression was positively correlated with multiple immune checkpoints (p < 0.05). The expression of DLGAP5 and KIF15 were significantly higher in A549, H1299, H1975, and PC-9 cell lines than that in BEAS-2B cell line.

Conclusion
High expression of the seven genes is positively correlated with poor prognosis of LUAD, and these genes are promising as prospective immunotherapy targets.
Genderspezifische Unterschiede in der Anästhesie und Schmerzbehandlung – eine Übersicht
Authors: Sinner Barbara 
Published: June 2023

ZusammenfassungFrauen und Männer unterscheiden sich in zahlreichen anästhesierelevanten Aspekten. Hierzu zählen nicht nur die Vorerkrankungen, sondern auch geschlechtsspezifische Unterschiede in der Pharmakodynamik und -kinetik verschiedener Medikamente. Hinzu kommen die unterschiedlichen und zyklusabhängigen Einflüsse der weiblichen Sexualhormone. Diese Übersichtsarbeit soll einen Einblick in die geschlechtsspezifischen Unterschiede in der Anästhesie und Schmerzbehandlung geben.
A new large-area hierarchical PPP-RTK service strategy
Authors: Cui Bobin , Jiang Xinyuan , Wang Jungang , Li Pan , Ge Maorong , Schuh Harald 
Published: June 2023

AbstractIntroducing precise atmosphere information into precise point positioning enables rapid ambiguity resolution and introduces a significant accuracy improvement. However, it can only be implemented in regions with dense networks and stable communication links. For larger areas, e.g., an intercontinental level, there is a conflict between the accuracy of corrections and the amount of atmosphere information to be disseminated. We develop a hierarchical augmentation mode to combine the advantages of the fitting model and region interpolation model to relieve the communication burden. Relying on the fitting model with fewer coefficients applied over large areas as the essential information, the unmodeled errors are calculated at each reference station, and further correction information is optional compensation depending on the magnitude of the unmodeled residuals. We perform the proposed models on 103 EUREF Permanent Network stations with 200-km station spacing and 84 stations as the external validation. The ionosphere and troposphere fitting models have an average accuracy of about 4.2 and 1.3 cm, respectively, under meteorologically calm conditions. The unmodeled error transmission determined by the magnitude of residuals can be reduced by 61% and 96% for the ionospheric and tropospheric delays, respectively, with respect to the legacy interpolation mode. Further compensation implemented, i.e., unmodeled residuals, can achieve instantaneous convergence for 83.6% of all solutions, and the overall initialization time is within 1.0 min. Thus, the proposed hierarchical positioning mode satisfies real-time positioning convergence requirements and significantly reduces massive corrections in communication.
Considerations for environmental biogeochemistry and food security for aquaculture around Lake Victoria, Kenya
Authors: Marriott A. L. , Osano O. F. , Coffey T. J. , Humphrey O. S. , Ongore C. O. , Watts M. J. , Aura C. M. 
Published: June 2023

AbstractThe impact of population expansion through economic growth and development has been identified as one of the key drivers of both water and sediment contamination from potentially harmful elements (PHEs). This presents a major hazard not only to aquatic ecosystems but local riparian communities and beyond who rely heavily on this natural resource for drinking water and fish—a valuable source of dietary micronutrients and protein. The present study measured biogeochemical concentration of PHEs in water, sediment and fish from locations pooled into four zones within Winam Gulf and Lake Victoria area of Kenya. Captured fish were used as a sentinel receptor of lake health to evaluate potential risks to fisheries and aquaculture food security. In water, concentrations of arsenic (As), cadmium (Cd), chromium (Cr), copper (Cu) and lead (Pb) were observed above the United States Environmental Protection Agency (US EPA) maximum contamination level drinking water guidelines (MCL), with aluminium (Al) observed above the Aquatic Life Criteria in all four zones. Similarly, sediment concentrations in all four zones exceeded the US EPA Effects range low (ERL) threshold guidelines for Cu, nickel (Ni), zinc (Zn) and Pb, with Cu, Zn and Pb classed at moderate contamination levels using the contamination factor. Fish tissue concentrations from the four zones were calculated using recommended daily intakes (RDI) and for PHEs as provisional maximum tolerable intakes (PMTIs) and indicated most macro- and micronutrients were at or below 10% RDI from aquaculture and wild fish, with Se indicating a greater RDI (16–29%) in all the zones. Contributions of PHEs to PMTIs were below threshold guidelines for both aquaculture and wild fish with only Cd, Cr and Pb levels being above the PMTI thresholds. There is a need to assess the long-term effects of persistent anthropogenic PHE input into Winam Gulf and the wider Lake Victoria basin. Continued monitoring of PHEs using both historical and more recent data will enable future management policies to be implemented through improved mitigation strategies to reduce their impact on water quality, fish health and subsequent human health.
Interparental Relationship Satisfaction from Nine Months to Nine Years and Children’s Socioemotional Competencies at Nine Years
Authors: Conica Mirela , Nixon Elizabeth , Quigley Jean 
Published: June 2023

AbstractThe quality of the interparental relationship bears important implications for children’s socioemotional development. Given evidence that relationship satisfaction among parents tends to decline over time this study examined how change in parents’ relationship satisfaction from nine-months-old until nine-years-old related to children’s socioemotional difficulties at nine-years-old. Participants were 2074 mothers, fathers, and their child (55.1% male) recruited through random sampling of the Child Benefit Registrar by Growing Up in Ireland cohort study. Mothers ranged in age from 18 to 40 years (M = 31.06, SD = 4.70) and fathers ranged in age from 18 to 60 years (M = 33.50, SD = 5.54). Mothers and fathers completed the Dyadic Adjustment Scale at nine-months-old and at nine-years-old whereas child socioemotional development was assessed via teacher report on the Strengths and Difficulties Questionnaire at nine-years-old. Residualised change analysis indicated that both parents experienced declines in relationship satisfaction from nine-months-old until nine- years-old. However, in families where initial levels of relationship satisfaction were high, there was no significant association between decline in satisfaction and child socioemotional difficulties. Conversely, in couples where initial levels of satisfaction were low, mothers, but not fathers, who experienced further declines had female, but not male, children with more socioemotional difficulties at nine years (β = −0.22,p = 0.01;R2 = 0.15, F = 2.31,p = 0.02). These findings highlight the need for carefully tailored interventions aimed at promoting couple relationship satisfaction during transition to parenthood such that the negative impact on children of any decline experienced over time can be mitigated.
Safety and Efficacy of Hizentra® Following Pediatric Hematopoietic Cell Transplant for Treatment of Primary Immunodeficiencies
Authors: Patel Niraj C. , Torgerson Troy , Thakar Monica S. , Younger M. Elizabeth M. , Sriaroon Panida , Pozos Tamara C. , Buckley Rebecca H. , Morris David , Vilkama Diana , Heimall Jennifer 
Published: June 2023

Abstract Primary immunodeficiency disease (PIDD) comprises a group of disorders of immune function. Some of the most severe PIDD can be treated with hematopoietic cell transplant (HCT). Hizentra® is a 20% liquid IgG product approved for subcutaneous administration in adults and children greater than 2 years of age with PIDD-associated antibody deficiency. Limited information is available on the use of Hizentra® in children following HCT for PIDD. A multicenter retrospective chart review demonstrated 37 infants and children (median age 70.1 [range 12.0 to 176.4] months) with PIDD treated by HCT who received Hizentra® infusions over a median duration of 31 (range 4–96) months post-transplant. The most common indication for HCT was IL2RG SCID (n = 16). Thirty-two patients switched from IVIG to SCIG administration, due to one or more of the following reasons: patient/caregiver (n = 17) or physician (n = 12) preference, discontinuation of central venous catheter (n = 16), desire for home infusion (n = 12), improved IgG serum levels following lower levels on IVIG (n = 10), and loss of venous access (n = 8). Serious bacterial infections occurred at a rate of 0.041 per patient-year while on therapy. Weight percentile increased by a mean of 16% during the observation period, with females demonstrating the largest gains. Mild local reactions were observed in 24%; 76% had no local reactions. One serious adverse event (death from sepsis) was reported. Hizentra® was discontinued in 15 (41%) patients, most commonly due to recovery of B cell function (n = 11). These data demonstrate that Hizentra® is a safe and effective option in children who have received HCT for PIDD.
Advances in the study of global forest wildfires
Authors: Li Tong , Cui Lizhen , Liu Lilan , Chen Yang , Liu Hongdou , Song Xiufang , Xu Zhihong 
Published: June 2023

Abstract
Purpose
Wildfire is one of the most important natural disturbances in forest and multi-vegetation ecosystems, directly or indirectly affecting the structural processes and functions of forest ecosystems with varying degrees. Wildfire releases vast amounts of carbon dioxide and other substances by destroying vegetation, making itself an important topic for the study of global change and environmental impacts. Therefore, a deeper understanding of this topic is particularly crucial for managing forest ecosystems.

Methods
This paper was based on a literature search of the Web of Science database for international forest wildfire research, utilizing bibliometric and quantity statistical analysis methods.

Results
The results show that forest wildfire research has been rapidly growing over the last 20 years, with the number of relevant articles generally increasing yearly at an average annual growth rate of about 22.45%. The US tops the list in terms of total and independent publications, with a total of 3111 articles (49.88%). The key journals publishing on this topic include 12 journals, Stephens S.L., Bergeron Y., and Lindenmayer D.B. are the key contributing authors to the field, and research institutions are primarily concentrated in the US Forest Service. Keyword co-occurrence analysis shows that current forest wildfire research is focused on seven main areas. This paper systematically reviewed the progress and hotspots of international forest wildfire research in recent decades, mainly focusing on occurrences, severity, management, and warning techniques for wildfires, as well as the impact of climate change and human activities on wildfires.

Conclusions
The study concludes that research trends in this field have undergone a significant evolution in recent decades. The future forest wildfire research moves towards a combination of typical mechanisms and large-scale effects across spatial and temporal scales, deep integration of aerospace and earth observations and precise simulations, discipline fusion, and couplings research. We believe that this study provides a comprehensive and systematic overview for future forest wildfire observation, prediction, management, and investigation of ecological effects.
Unlocking and accelerating transformations to the SDGs: a review of existing knowledge
Authors: Allen Cameron , Malekpour Shirin 
Published: June 2023

AbstractAs we approach the 2030 deadline to achieve the Sustainable Development Goals (SDGs), there is a growing sense of urgency around the need to accelerate the necessary transformations. These encompass a broad range of systems and require fundamental changes in system goals and design. In this paper, we undertake a narrative review of the literature relating to the acceleration of transformations and offer a framework for unlocking and accelerating transformations to the SDGs. While there is no blueprint for acceleration, there is an expanding knowledge base on important dynamics, impediments and enabling conditions across diverse literatures which can help to inform strategic interventions by actors. The emerging literature on positive tipping points and deep leverage points identifies opportunities to rewire systems design so that important system feedbacks create the conditions for acceleration. Transformation takes time and actors will need to build momentum to reorient systems around new goals, informed by knowledge of common policy, technology and behavioural feedbacks that govern system dynamics. Where resistance is strong, actors can seek to augment system design in ways that weaken balancing feedbacks that stabilise existing system configurations and strengthen reinforcing feedbacks that promote emerging system configurations oriented towards the SDGs. Well-designed and sequenced interventions can promote innovation and behaviour change and build and maintain political support. This can build critical enabling conditions and push systems towards large-scale tipping points, paving the way for decisive policy action that is crucial for triggering acceleration. We conclude by highlighting gaps and priorities for further research.