bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nasopharyngeal Cancer Incidence and Mortality in 185 Countries in 2020 and the Projected Burden in 2040: Population-Based Global Epidemiological Profiling
Authors: Zhang Yanting , Rumgay Harriet , Li Mengmeng , Cao Sumei , Chen Wanqing 
Published: September 2023

Background
Nasopharyngeal cancer (NPC) is one of the most common head and neck cancers.

Objective
This study describes the global epidemiological profiles of NPC incidence and mortality in 185 countries in 2020 and the projected burden in 2040.

Methods
The estimated numbers of NPC cases and deaths were retrieved from the GLOBOCAN 2020 data set. Age-standardized incidence rates (ASIRs) and age-standardized mortality rates (ASMRs) were calculated using the world standard. The future number of NPC cases and deaths by 2040 were estimated based on global demographic projections.

Results
Globally, approximately 133,354 cases and 80,008 deaths from NPC were estimated in 2020 corresponding to ASIRs and ASMRs of 1.5 and 0.9 per 100,000 person-years, respectively. The largest numbers of both global cases and deaths from NPC occurred in Eastern Asia (65,866/133,354, 49.39% and 36,453/80,008, 45.56%, respectively), in which China contributed most to this burden (62,444/133,354, 46.82% and 34,810/80,008, 43.50%, respectively). The ASIRs and ASMRs in men were approximately 3-fold higher than those in women. Incidence rates varied across world regions, with the highest ASIRs for both men and women detected in South-Eastern Asia (7.7 and 2.5 per 100,000 person-years, respectively) and Eastern Asia (3.9 and 1.5 per 100,000 person-years, respectively). The highest ASMRs for both men and women were found in South-Eastern Asia (5.4 and 1.5 per 100,000 person-years, respectively). By 2040, the annual number of cases and deaths will increase to 179,476 (46,122/133,354, a 34.58% increase from the year 2020) and 113,851 (33,843/80,008, a 42.29% increase), respectively.

Conclusions
Disparities in NPC incidence and mortality persist worldwide. Our study highlights the urgent need to develop and accelerate NPC control initiatives to tackle the NPC burden in certain regions and countries (eg, South-Eastern Asia, China).
Analisis Pengaruh Pengungkapan Inovasi Hijau terhadap Profitabilitas pada Perusahaan Nonkeuangan
Authors: Amalia Elsa 
Published: September 2023

Tujuan – Tujuan penelitian ini adalah untuk menganalisis pengaruh pengungkapan inovasi hijau (produk hijau dan proses hijau) terhadap profitabilitas serta membuktikan apakah adanya peran pelaporan keberlanjutan perusahaan akan mengubah hasil hubungan pengungkapan inovasi hijau terhadap profitabilitas.Metode Penelitian – Metode penelitian ini menggunakan pendekatan kuantitatif dengan menggunakan data sekunder. Data yang digunakan dalam penelitian ini adalah laporan tahunan seluruh perusahaan nonkeuangan yang terdaftar di Bursa Efek Indonesia (BEI) dari 2017 hingga 2021 serta database OSIRIS sebagai sumber pengambilan data penelitian. Pengambilan sampel dilakukan secara purposive sampling dan didapatkan sampel sebanyak 1.619 perusahaan.Temuan – Temuan penelitian ini menunjukkan bahwa penerapan inovasi hijau berpengaruh signifikan positif terhadap profitabilitas. Hal ini membuktikan bahwa perusahaan melakukan inovasi produk hijau, inovasi tersebut akan meningkatkan profit yang didapatkan perusahaan, sedangkan inovasi proses hijau berpengaruh signifikan negatif terhadap profitabilitas. Hal ini terjadi karena dalam mengadopsi dan mengganti peralatan canggih untuk meningkatkan proses produksi yang ramah lingkungan perusahaan akan lebih banyak mengeluarkan biaya. Adanya laporan keberlanjutan tidak memengaruhi hubungan antara pengungkapan inovasi hijau yang dilakukan perusahaan dalam meningkatkan profitabilitas. Hal ini terjadi karena laporan keberlanjutan terkait dengan inovasi produk dan proses hijau tidak representatif dengan realisasinya.Orisinalitas – Penelitian ini menambahkan adanya peran pelaporan keberlanjutan pada pengaruh hubungan antara inovasi hijau terhadap profitabilitas. Penelitian ini menggunakan data panel unbalanced untuk mendapatkan sampel yang dapat digeneralisasikan karena masih sedikit perusahaan yang melakukan pengungkapan laporan keberlanjutan lengkap dari tahun ke tahun. Kata Kunci: Inovasi Produk Hijau, Inovasi Proses Hijau, Pelaporan Keberlanjutan, Profitabilitas
Eksplorasi Peran Inspektorat dalam Pelaksanaan Fungsi Pengawasan terhadap Pengelolaan Dana Desa: Studi Kasus pada Inspektorat Daerah Kabupaten Gunungkidul
Authors: Rahmawati Lathifah Nur Aini , Suwardi Eko 
Published: September 2023

>Penelitian ini bertujuan untuk mengeksplorasi peran inspektorat daerah dalam pelaksanaan pengawasan keuangan khususnya berkaitan dengan pengelolaan dana desa, mengidentifikasi kendala yang dihadapi oleh inspektorat daerah secara keseluruhan dan mendalam serta upaya yang dilakukan untuk mengatasi kendala tersebut. Metode penelitian yang digunakan dalam penelitian ini adalah metode penelitian kualitatif dengan pendekatan studi kasus. Sampel dari penelitian ini merupakan auditor internal di Inspektorat Daerah Kabupaten Gunungkidul, serta staf dari dinas dan pemerintah desa di Kabupaten Gunungkidul. Berdasarkan teori peran organisasi, ditemukan bahwa Kepala daerah mengirimkan peran pengawasan kepada Inspektorat Daerah Kabupaten Gunungkidul sebagai pemegang peran. Inspektorat Daerah Kabupaten Gunungkidul telah melaksanakan peran pengawasan sesuai dengan peraturan dan pedoman yang berlaku. Inspektorat Daerah menghadapi konflik peran dan peran berlebih yang dilatarbelakangi oleh kendala internal menyebabkan peran pengawasan belum optimal. Inspektorat Daerah Kabupaten Gunungkidul juga menghadapi kendala dari eksternal dalam melaksanakan peran pengawasan terhadap pengelolaan dana desa. Peneliti menemukan beberapa upaya yang dilakukan oleh Inspektorat Daerah Kabupaten Gunungkidul untuk mengatasi kendala tersebut.
Effect of Postmenopausal Hormone Therapy on Glucose Regulation in Women With Type 1 or Type 2 Diabetes: A Systematic Review and Meta-analysis
Authors: Speksnijder Esther M. , ten Noever de Brauw Gaby V. , Malekzadeh Arjan , Bisschop Peter H. , Stenvers Dirk Jan , Siegelaar Sarah E. 
Published: September 2023

BACKGROUND
Blood glucose regulation in women with diabetes may change during and after menopause, which could be attributed, in part, to decreased estrogen levels.

PURPOSE
To determine the effect of postmenopausal hormone therapy (HT) on HbA1c, fasting glucose, postprandial glucose, and use of glucose-lowering drugs in women with type 1 and women with type 2 diabetes.

DATA SOURCES
We conducted a systematic search of MEDLINE, Embase, Scopus, the Cochrane Library, and the ClinicalTrials.gov registry to identify randomized controlled trials (RCTs).

STUDY SELECTION
We selected RCTs on the effect of HT containing estrogen therapy in postmenopausal women (≥12 months since final menstrual period) with type 1 or type 2 diabetes.

DATA EXTRACTION
Data were extracted for the following outcomes: HbA1c, fasting glucose, postprandial glucose, and use of glucose-lowering medication.

DATA SYNTHESIS
Nineteen RCTs were included (12 parallel-group trials and 7 crossover trials), with a total of 1,412 participants, of whom 4.0% had type 1 diabetes. HT reduced HbA1c (mean difference −0.56% [95% CI −0.80, −0.31], −6.08 mmol/mol [95% CI −8.80, −3.36]) and fasting glucose (mean difference −1.15 mmol/L [95% CI −1.78, −0.51]).

LIMITATIONS
Of included studies, 50% were at high risk of bias.

CONCLUSIONS
When postmenopausal HT is considered for menopausal symptoms in women with type 2 diabetes, HT is expected to have a neutral-to-beneficial impact on glucose regulation. Evidence for the effect of postmenopausal HT in women with type 1 diabetes was limited.
Safety and Efficacy of Sustained Automated Insulin Delivery Compared With Sensor and Pump Therapy in Adults With Type 1 Diabetes at High Risk for Hypoglycemia: A Randomized Controlled Trial
Authors: Renard Eric , Joubert Michael , Villard Orianne , Dreves Bleuenn , Reznik Yves , Farret Anne , Place Jerome , Breton Marc D. , Kovatchev Boris P. ,   iDCL Trial Research Group
Published: September 2023

OBJECTIVE
Assess the safety and efficacy of automated insulin delivery (AID) in adults with type 1 diabetes (T1D) at high risk for hypoglycemia.

RESEARCH DESIGN AND METHODS
Participants were 72 adults with T1D who used an insulin pump with Clarke Hypoglycemia Perception Awareness scale score &gt;3 and/or had severe hypoglycemia during the previous 6 months confirmed by time below range (TBR; defined as sensor glucose [SG] reading &lt;70 mg/dL) of at least 5% during 2 weeks of blinded continuous glucose monitoring (CGM). Parallel-arm, randomized trial (2:1) of AID (Tandem t:slim ×2 with Control-IQ technology) versus CGM and pump therapy for 12 weeks. The primary outcome was TBR change from baseline. Secondary outcomes included time in target range (TIR; 70–180 mg/dL), time above range (TAR), mean SG reading, and time with glucose level &lt;54 mg/dL. An optional 12-week extension with AID was offered to all participants.

RESULTS
Compared with the sensor and pump (S&P), AID resulted in significant reduction of TBR by −3.7% (95% CI −4.8, −2.6), P &lt; 0.001; an 8.6% increase in TIR (95% CI 5.2, 12.1), P &lt; 0.001; and a −5.3% decrease in TAR (95% CI −87.7, −1.8), P = 0.004. Mean SG reading remained similar in the AID and S&P groups. During the 12-week extension, the effects of AID were sustained in the AID group and reproduced in the S&P group. Two severe hypoglycemic episodes occurred using AID.

CONCLUSIONS
In adults with T1D at high risk for hypoglycemia, AID reduced the risk for hypoglycemia more than twofold, as quantified by TBR, while improving TIR and reducing hyperglycemia. Hence, AID is strongly recommended for this specific population.
In the Struggle against “Tactless Liberalism”: A.K. Kirkor and the Newspaper Novoe Vremya on the Consequences of the Great Reforms in the Late 1860s – Early 1870s
Authors: Завьялова О. О. 
Published: September 2023

В статье представлен анализ социально-экономических и политических идей, отраженных на страницах газеты «Новое время» в конце 1860-х – начале 1870-х гг., когда ее издателем-редактором являлся виленский интеллектуал, представитель пророссийски ориентированной общественности Северо-Западного края А.К. Киркор. Особое внимание уделяется анализу его политических воззрений на проблемы управления регионом в переломную эпоху Великих реформ 1860-х – 1870-х гг., а также оценке, данной основным правительственным преобразованиям в передовых статьях «Нового времени», и попыткам газеты повлиять на формирующееся общественное мнение по данной проблеме в период 1868–1871 гг. Позицию редакционного отдела газеты и ее издателя-редактора Киркора при характеристике социально-экономических трансформаций пореформенного периода отличал идейный синкретизм, который основывался на сочетании либеральных и сословно-консервативных ценностных установок и определялся сложившейся в Северо-Западном крае во второй половине 1860-х гг. политической и социокультурной ситуацией. Делается вывод о том, что в рамках деятельности газеты своими рекомендациями местного «эксперта» Киркор стремился скорректировать национальную политику в отношении региона, указывая на более гибкие методы его обрусения, учитывавшие нужды и потребности как местной социальной элиты, так и недоминирующих этнических групп.
The article presents the analysis of socio-economic and political ideas reflected in the pages of the newspaper Novoe Vremya in the late 1860s – early 1870s, when A.K. Kirkor, a Vilna intellectual, representative of the pro-Russian-oriented public of Northwestern Krai, was its publisher and editor. Particular attention is paid to the analysis of Kirkor’s political views on the problems of governing the region in the critical era of the Great Reforms in the 1860s–70s, as well as to the assessment of the main governmental transformations in the editorials of Novoe Vremya and the newspaper’s attempts to influence the public opinion on that issue in the period between 1868 and 1871. The position of the editorial board of the newspaper and its publisher and editor Kirkor in characterizing the socio-economic transformations of the post-reform period could be characterized by ideological syncretism, which was based on a combination of liberal and class conservative values and was mainly determined by the political and socio-cultural situation in Northwestern Krai in the second half of the 1860s. It is concluded that within the framework of the newspaper’s work, Kirkor provided his recommendations of a local expert and thus sought to adjust the national policy in the region, pointing to more flexible methods of its Russification, which would take into account the needs and requirements of both the local social elite and the non-dominant ethnic groups of the region.
El oro y los “pesos de oro” en los inicios de Nueva España. Una propuesta de reinterpretación
Authors: Rivero Hernández Iván 
Published: September 2023

Desde su arribo al territorio americano, los españoles emplearon los referentes propios de la realidad monetaria de la que procedían para operar en un contexto económico carente de moneda. Esta adecuación derivó en el uso de ciertos conceptos específicos que, en el caso del oro, luego habrían de retomarse de manera oficial tras el establecimiento de las casas de moneda, si bien con nuevas modificaciones y valores. Esto implica la existencia de “pesos de oro” distintos según el momento, aspecto no siempre reconocido en los estudios que dan luz sobre la etapa formativa novohispana. Con base en las cuentas de tesorería y los registros de fundición de Nueva España, este artículo evidencia tal diferencia y ofrece una vía para su dimensión económica.
Olive Grove Landscapes in Andalusia: In Search of Synergies Between Agrarian Cultural Heritage and Rural Development
Authors: Martínez José Domingo Sánchez 
Published: September 2023

Summary
This paper analyses the strategy developed thus far to have Andalusian olive-growing landscapes included as a Cultural Landscape on the World Heritage List (UNESCO). The research method used is descriptive, reflexive and prospective, and seeks to achieve a systematic and holistic overview of a complex reality. In addition to the corresponding bibliographical review, the research has been nourished by qualitative information from land surveys (field visits) and interviews with experts consulted during the preparation of the two technical dossiers of the candidacy produced so far. The results include the rationale for Outstanding Universal Value and the basis of the protection and management plan for the property. Subsequently, the paper discusses the possibilities for rural development that can be derived from this initiative through the virtuous interactions between the property, the region and the food (olive oil) obtained from traditional olive groves.
Stakeholder Ecosystems and Corporate Sustainability: A Nexus for Value Creation in the Age of Sustainability
Authors: Gorski Andra-Teodora , Dumitraşcu Dănuț Dumitru 
Published: September 2023

Abstract
The present-day interconnected global society has seen a diminished significance of borders and a growing interdependence between companies and their stakeholders. For every organization the influence wielded by these key stakeholders plays a pivotal role. The interdependence between stakeholders and corporate sustainability forms the foundation for generating economic, social, and environmental performance, as well as long-term sustainable value for the stakeholder ecosystem. The aim of the paper is to examine significant aspects related to the stakeholder dimension of corporate sustainability. This research employs a methodology that draws upon both literature review and bibliometric analysis, performed using VOSviewer. The research has identified stakeholder engagement as a critical and emerging theme. Moreover, a modern stakeholder approach is essential for understanding stakeholder dynamics holistically. Amid current challenges, a growing discourse advocates a multi-stakeholder approach, recognizing wider society and the natural environment as important stakeholders. In the context of sustainability, key trends include: promoting a pro-sustainability mindset among all stakeholders, fostering shared interests in sustainability, and empowering stakeholders to advocate for nature and sustainable development. The paper concludes with recommendations derived from the research results, providing insights for academics, researchers, and managers in formulating and implementing corporate strategies aligned with sustainability opportunities and challenges.
Entrepreneurship in Romania: Opportunities and Challenges
Authors: Lucian Paul , Șoaită Antonela-Ioana 
Published: September 2023

Abstract
Is the development of entrepreneurship one of the solutions to the economic and development problems facing Romania? The answer is related to the identification of solutions to support its development. Romania is an Eastern European country that faces many problems, not only economic ones, but also social and political ones, and which does not favor a coherent and predictable entrepreneurial environment, which poses both opportunities and challenges for those who want to start or develop a business. Today there are many entrepreneurs in Romania who have created successful businesses in various fields, contributing to economic growth and new jobs. And yet, Romania ranks last among the other EU member states in terms of entrepreneurial development. Reducing the gap requires finding not only quick but also effective solutions to the problems they face related to bureaucracy, corruption, legislation and financing access.
Assessing the Situation of Micro, Small, and Medium-Sized Enterprises in the Emerging Markets of Egypt Under COVID-19 Implications
Authors: Saad Nourhan Ahmed , Mlaker Kac Sonja , Elgazzar Sara 
Published: September 2023

AbstractMicro, Small, and Medium-sized Enterprises (MSMEs) play a vital role in emerging economies, thus this research aims at assessing the current situation of Egyptian MSMEs under COVID-19 pandemic and identifying the role of Egyptian MSMEs in economic growth and development. This research adopted qualitative design; 24 semi-structured interviews were conducted with different eco-system stakeholders and MSMEs’ managers using content analysis to analyse collected data based on NVivo software. The findings revealed the importance of MSMEs sector in the emerging markets as well as global ones. Additionally, MSMEs play a significant role in enhancing country’s economic growth and development, particularly in GDP, job opportunities, domestic products/services, national income, sub-contractor, and individual/society welfare. Furthermore, the findings identify the main challenges that face Egyptian MSMEs under COVID-19 implications through analysing the four main strategic factors and concluded by policy recommendations that could be implemented by MSMEs’ owners to take full advantage in the Egyptian context and their contribution on country’s economic growth.
Entrepreneurial Awareness and Entrepreneurial Intention: Understanding the Role of Family and School
Authors: Widyastuti Umi , Purwana Dedi , Respati Dwi Kismayanti , Zulaihati Sri 
Published: September 2023

AbstractThis study aims to examine the factors that affect entrepreneurial awareness and intention in Junior High School students This research used a quantitative approach with PLS-SEM by considering that the model employed unobserved variables and measured using different scale. This research applied convenience sampling and obtained 97 Junior High School students spread across Jakarta, Bogor, Depok, Tangerang, and Bekasi (the Greater Jakarta) as the research samples. Furthermore, this research proved that entrepreneurial awareness and self-efficacy significantly affected entrepreneurial intention. On the other hand, entrepreneurship education, financial knowledge, and entrepreneurship experience did not significantly affect entrepreneurial intention. Meanwhile, entrepreneurial awareness was influenced by financial knowledge. The results proved that financial knowledge mediated the effects of financial socialization on entrepreneurial intention and entrepreneurial awareness. Meanwhile, financial knowledge had some effects on entrepreneurial intention through entrepreneurial awareness. The empirical results emphasized the importance of the role of families and schools in building entrepreneurial awareness and intention.
Políticas públicas no Brasil: história, evolução, situação e estigma
Authors: Ribeiro Rafael Bernardon , Cordeiro Júnior Quirino 
Published: September 2023

Os últimos anos têm sido marcados por vitórias em prol da saúde mental em decorrência das mudanças ocorridas nas Políticas Públicas em Saúde Mental no Brasil. Em 2020, a Associação Brasileira de Psiquiatria em parceria com o Ministério da Saúde, lançou o Mentalize, uma série de palestras com o objetivo de desmistificar os transtornos mentais e dessa forma diminuir o estigma. Quais as principais mudanças temos visto na atenção dada à saúde mental? Quais as principais medidas que devem ser tomadas para o oferecimento de tratamento de qualidade a todos? Quais as principais medidas devem ser tomadas para diminuição do estigma? Essas e outras questões serão respondidas no ABP TV pelos doutores Rafael Bernardon e Quirino Cordeiro.
Transtornos alimentares: o impacto do distanciamento social
Authors: Segal Adriano , Silva Antônio Geraldo da , Appolinario Jose Carlos Borges , Cordás Táki Athanássios 
Published: September 2023

A pandemia de Covid-19 pode servir de gatilho para o desenvolvimento ou agravamento de doenças psiquiátricas. Entre os comportamentos mais alterados durante o período, a relação com a alimentação pode ser diretamente impactada pelo tempo que passamos a mais em casa. Como administrar as escolhas por uma alimentação mais saudável durante a pandemia? De que forma os comportamentos alimentares podem indicar o agravamento de doenças psiquiátricas como depressão e ansiedade? Pacientes que sofrem com transtornos alimentares podem ter recaídas durante o período em casa? Estas e outras perguntas serão respondidas pelos nossos convidados nessa edição.
Atendimento médico psiquiátrico a distância em tempos de Covid-19
Authors: Silva Antonio Geraldo , Cavalcanti Emmanuel Fortes Silveira , Rodrigues Filho Salomão 
Published: September 2023

A pandemia de Covid-19, que se instalou em todo o mundo desde março, traz a necessidade de adaptação do atendimento em diversas especialidades médicas. Na psiquiatria, este panorama também se apresenta como um desafio para médicos da especialidade e também para pacientes psiquiátricos. Quais os limites técnicos e éticos para aplicação da telemedicina em psiquiatria? Como os médicos devem se adaptar para oferecer o melhor atendimento possível a seus pacientes? De que forma atuar dentro da ética médica ao aderir à telemedicina? Estas e outras perguntas serão respondidas no agora no programa ABPTV. Participam do programa os doutores Antônio Geraldo da Silva, Emmanuel Fortes e Salomão Rodrigues Filho.
Como cuidar da saúde mental das crianças e adolescentes | Covid-19
Authors: Silva Antônio Geraldo da , Soares Júnior Antônio Marcos Alvim , Porto Deisy Mendes , Lucas Lílian Schwanz , Pinheiro Mayra Isabel Correia 
Published: September 2023

No sábado, dia 11 de abril, a situação de pandemia decretada pela Organização Mundial da Saúde - OMS completou um mês. No Brasil, as primeiras restrições de circulação e orientações de distanciamento social começaram no dia 16 de março, em São Paulo e no Rio de Janeiro. Segundo dados da Organização das Nações Unidas para a Educação, Ciência e Cultura - UNESCO, metade dos estudantes de todo o mundo estão sem aulas devido à pandemia, ou seja, cerca de 850 milhões de crianças e adolescentes. Com isso, há também uma preocupação com a saúde mental desse público, que teve sua rotina de atividades interrompida e, agora, está em casa. Por isso, o ABPTV da série especial sobre o Covid-19 de hoje aborda o tema "Covid-19: como cuidar da saúde mental das crianças".