bluuebunny/crossref_metadata_2025_split huggingface dataset:
Penyelesaian Penyebab Bottle Neck Article SOT 2875 Pada Proses Join Collar di PT Ameya Livingstyle Indonesia
Authors: Eddy Yulius Sarjono 
Published: May 2023

PT Ameya Livingstyle Indonesia merupakan perusahaan garmen berskala internasional yang telah berkembang sejak tahun 2006, terletak di daerah Pajangan, Bantul Yogyakarta. Kata “Ameya” sendiri diambil dari bahasa Jepang “Bountiful” yang artinya PT Ameya Livingstyle Indonesia diharapkan dapat memberikan kelimpahan untuk stakeholdernya meliputi pemilik, karyawan, pembeli, pemasok, pemerintah dan lingkungan. Produk yang diproduksi oleh PT Ameya yaitu produk yang memiliki kualitas tinggi antara lain men shirt, ladies blouses atau dresses dan skirts. PT Ameya livingstyle Indonesia menjadi perusahaan yang berkembang dan tumbuh dengan pesat di berbagai bidang fasilitas garmen manufaktur, dengan jumlah karyawan ± 2.500 orang dan jumlah order minimum sebanyak 3.000 pcs/style, serta jumlah kapasitas produksi 300.000-350.000 per bulannya. Proses produksi dan pengendalian mutu mulai dari bahan baku, produk setengah jadi sampai menjadi suatu produk jadi (garmen). Tujuan dari pengendalian mutu adalah meminimalisir produk yang tidak sesuai dengan standar mutu yang diinginkan (second quality), dan bisa mengendalikan, menilai kualitas, sehingga konsumen merasa puas dan perusahaan merasa tidak dirugikan. Pada proses produksi garmen, setiap tahapan proses dilaksanakan pengendalian mutu dari pihak Quality Control, menganalisis masalah yang terjadi dalam proses produksi melalui pengamatan secara langsung dan mencari penyelesaiannya. Selama melakukan pengamatan khususnya di departemen sewing line 11 dengan style yang diproduksi article SOT 2875 ditemukan kendala yang menghambat jalannya proses produksi (bottle neck) pada proses join collar, terdapat 4 faktor penyebab bottle neck yaitu manusia (man), mesin (machine), bahan (material), dan faktor utama yang menyebabkan bottle neck pada proses join collar to body yaitu metode (method) jahit yang kurang efektif. Penyelesaian faktor tersebut yaitu merubah metode penjahitan join collar to body menjadi 2 langkah. Pertama beberapa operator melakukan join collar to body, kedua operator lainnya melakukan close collar, sehingga dapat meminimalisir bottle neck dan proses produksi dapat berjalan dengan lancar.
Ortez ve Protez Bölümü Öğrencilerinde Mesleki Farkındalık Düzeylerinin Belirlenmesi
Authors: DEMİRDEL Senem , YILDIRIM ŞAHAN Tezel , ÜN YILDIRIM Necmiye 
Published: May 2023

Bu çalışma Sağlık Bilimleri Üniversitesi Gülhane Sağlık Bilimleri Fakültesi Ortez ve Protez Bölümü öğrencilerinin mesleki farkındalık
düzeylerini değerlendirmek amacıyla planlandı. Çalışmaya 86 Ortez ve Protez bölümü öğrencisi katıldı. Bu kesitsel çalışmada çevrimiçi
form kullanılarak gönüllü öğrencilerin tanımlayıcı özellikleri sorgulandıktan sonra 17 çoktan seçmeli sorudan oluşan, yazarlar tarafından
literatür taranarak oluşturulan mesleki farkındalık anketi uygulandı. Ayrıca mesleki farkındalığı etkileyebileceği için öğrencilerin meslekle
ilgili yaptıkları araştırmalar, bu bölümü tercih etme nedeni gibi parametreler sorgulandı. Katılımcıların bölüme yerleşmekten dolayı
duydukları memnuniyet düzeyleri de soruldu. Mesleki farkındalık anketinin sorularının %54,3’üne doğru cevap verildiği görüldü. İkinci
sınıf öğrencilerinin doğru yanıt oranları anlamlı düzeyde daha fazla idi (p
Design of Topology‐Controlled Polyethers toward Robust Cooperative Hydrogen Bonding
Authors: Kim Junhee , Choi Soonyoung , Baek Jinsu , Park Yong Il , Kim Jin Chul , Jeong Ji‐Eun , Jung Hyocheol , Kwon Tae‐Hyuk , Kim Byeong‐Su , Lee Sang‐Ho 
Published: May 2023

AbstractTopology control of polymers is critical for determining their physical properties and potential applications; in particular, topologies that incorporate numerous hydrogen bonding (H‐bonding) donors and acceptors along the polymer chains considerably influence the formation of different inter‐ and intramolecular H‐bonding motifs. In this study, the high‐level control of inter‐ and intramolecular H‐bonding is investigated in topology‐controlled poly(glycidoxy carbonyl benzoic acid)s (PGCs). Three types of topology‐controlled PGCs (i.e., linear, hyperbranched, and branched cyclic structures having a similar degree of polymerization) are prepared by introducing aromatic carboxylic acids into the corresponding polyglycidols (PGs) via quantitative post‐polymerization modification with phthalic anhydride. The obtained three types of PGCs demonstrated the high‐level interplay between the inter‐ and intramolecular H‐bonding in polymer chains by exhibiting the pH‐dependent self‐association properties in the solution state and the strong adhesion properties in the bulk state with high transparency. Interestingly, the dramatically enhanced adhesive property by 2.6‐fold is demonstrated by simple mixing of branched cyclic PGC and topology‐controlled PGs to promote the cooperative H‐bonding between polymer chains. The new class of cooperative H‐bonding is anticipated between topology‐controlled polymers to contribute to the development of advanced adhesive and the high potential in biological and biomedical applications due to its excellent biocompatibility.
Awakening Allies for Breaking Microenvironment Barriers: NIR‐II Guided Orthogonal Activation of Tumor‐Infiltrating Mast Cells for Efficient Nano‐Drug Delivery
Authors: Wang Qingyuan , Yang Haiyan , Liu Yuan , Zhou Zhaoxi , Zhang Xu , Sang Mingyi , Xu Feng , Song Lebin , Xia Tiansong , Zhang Yue , Wei Jifu , Zhang Xiaobo , Ding Qiang 
Published: May 2023

AbstractMast cells (MCs), powerful immune cells that heavily infiltrate cancer cells, play a crucial role in tumor formation. Activated MCs can release histamine and a family of proteases through degranulation effects, concurrently achieving endothelial junction weakening and stromal degradation of the tumor microenvironment, thereby clearing the obstacles for nano‐drug infiltration. To achieve precise activation of tumor‐infiltrating MCs, orthogonally excited rare earth nanoparticles (ORENP), with two channels, are introduced for the controllable stimulating drugs release wrapped in “photocut tape”. The ORENP can emit near‐infrared II (NIR‐II) for image tracing for tumor localization in Channel 1 (808/NIR‐II) and allows energy upconversion to emit ultraviolet (UV) light for releasing drugs for MCs stimulation in Channel 2 (980/UV). Finally, the combined use of chemical and cellular tools enables clinical nano‐drugs to achieve a significant increase in tumor infiltration, thereby enhancing the efficacy of nano‐chemotherapy.
Entangling of Peptide Nanofibers Reduces the Invasiveness of SARS‐CoV‐2
Authors: Yang Pei‐Pei , Ye Xin‐Wei , Liu Mei‐Qin , Yang Jin‐Xuan , Feng Xiao‐Li , Li Yi‐Jing , Zhang Kuo , Liang Hong‐Wen , Yi Yu , Wang Lei , Liu Yi‐Xuan , Yang Xing‐Lou , Shi Zheng‐Li , Feng Li‐Qiang , Chen Ling , Xue Yintong , Pan‐Hammarström Qiang , Wang Hao , Zhao Yuliang 
Published: May 2023

AbstractThe viral spike (S) protein on the surface of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) binds to angiotensin‐converting enzyme 2 (ACE2) receptors on the host cells, facilitating its entry and infection. Here, functionalized nanofibers targeting the S protein with peptide sequences of IRQFFKK, WVHFYHK and NSGGSVH, which are screened from a high‐throughput one‐bead one‐compound screening strategy, are designed and prepared. The flexible nanofibers support multiple binding sites and efficiently entangle SARS‐CoV‐2, forming a nanofibrous network that blocks the interaction between the S protein of SARS‐CoV‐2 and the ACE2 on host cells, and efficiently reduce the invasiveness of SARS‐CoV‐2. In summary, nanofibers entangling represents a smart nanomedicine for the prevention of SARS‐CoV‐2.
Excimer‐Mediated Ultrafast Intermolecular Nonradiative Decay Enables Giant Photothermal Performance for Optimized Phototheranostic
Authors: Miao Xiaofei , Yao Weiyun , Chen Ruizhe , Jia Mingxuan , Ren Can , Zhao Hui , He Tingchao , Fan Quli , Hu Wenbo 
Published: May 2023

AbstractDeveloping organic photothermal materials (OPMs) with high photothermal performance for phototheranostic mainly focus on the manipulation of intramolecular nonradiative (intraNR) decay, which often requires quite complicated and time‐consuming molecular engineering. In addition to intraNR decay, intermolecular nonradiative (interNR) decay is equally important and more convenient in governing photothermal performance. However, controlling interNR decay remains challenging due to the limited understanding of their origin and dynamics. Here, systemic investigation of intraNR and interNR decay directs the first demonstration of simple manipulation of interNR decay to produce a giant photothermal performance for optimized phototheranostic. Among three designed polymers with varying fluorine substitution, structure–performance studies reveal a dimer‐initiated interNR decay to improve photothermal performance. Dimer is formed by intermolecular CF···H hydrogen bond. This finding inspires a simple aggregation control strategy to form excited dimer, namely, excimer. It initiates an ≈100‐fold enhancement in interNR decay rate over conventional intraNR decay to produce ultrahigh photothermal conversion efficiency of 81% for efficient photoacoustic imaging‐guided photothermal therapy in vivo. This study provides insights into interNR decay in achieving a giant photothermal effect and paves a convenient way to develop high‐performance OPMs.
High‐Throughput CRISPR/Cas9 Mediated Gene Editing of Primary Human T Cells in a Microfluidic Device for Cellular Therapy Manufacturing
Authors: Welch Michaela , Flusberg Deborah A. , Hsi Peter , Haroutunian Nerses J. , Santos Jose A. , Kim Ernest S. , Markovic Stacey , Coppeta Jonathan R. , Lissandrello Charles A. , Balestrini Jenna L. , Tandon Vishal 
Published: May 2023

AbstractAutologous cellular therapies have been highly successful in treating hematological cancers and have the potential to be used for a variety of indications. Manufacturing these therapies rapidly and at low cost remains a major challenge. A key bottleneck in cellular therapy manufacturing is genetic modification of target cells, which is often done using viral vectors. Because vectors are expensive to develop and produce, non‐viral gene transfer using electroporation is emerging as a preferred transfection method for next‐generation therapies. However, most commercial electroporation systems are built for research use rather than large‐scale clinical manufacturing. The microfluidic, continuous‐flow electroporation device presented here offers several advantages including large‐scale and high throughput processing, high performance, and the potential for automation. It transfects primary human T cells with Cas9‐guide ribonucleic acid (RNA) ribonucleoprotein complexes (RNP) and messenger RNA (mRNA) with up to 99–100% efficiency and minimal impact on viability. In addition, this device transfects 3.5 kbp plasmid deoxyribonucleic acid with up to 86% efficiency after preliminary optimization studies. A single microchannel can deliver a total cellular processing throughput of up to 9.6 billion per hour. The combination of high throughput and high performance enables the scale of processing required for future “off‐the‐shelf” allogeneic cellular therapies.
High‐Entropy Surface Complex Stabilized LiCoO2 Cathode
Authors: Tan Xinghua , Zhang Yongxin , Xu Shenyang , Yang Peihua , Liu Tongchao , Mao Dongdong , Qiu Jimin , Chen Zhefeng , Lu Zhaoxia , Pan Feng , Chu Weiguo 
Published: May 2023

AbstractElevating the charge voltage of LiCoO2 increases the energy density of batteries, which is highly enticing in energy storage implementation ranging from portable electronics to e‐vehicles. However, hybrid redox reactions at high voltages facilitate oxygen evolution, electrolyte decomposition and irreversible phase change, and accordingly lead to rapid battery capacity decay. Here significantly improved high‐voltage cycling stability of Mg‐Al‐Eu co‐doped LiCoO2 is demonstrated. It is found that element co‐doping induces a near‐surface high‐entropy zone, including an innately thin disordered rock‐salt shell and a dopant segregation surface. The high‐entropy complex can effectively suppress oxygen evolution and near‐surface structure deconstruction. The phase change reversibility between O3 and H1‐3 and thermal stability of the cathode are greatly enhanced as well. As a result, the co‐doped LiCoO2 exhibits a remarkable cycling performance, retaining 86.3% and 72.0% of initial capacity over 800 and 2000 cycles, respectively, with a high cut‐off voltage of 4.6 V. The feasible co‐doping approach broadens the perspective for the development of stable lithium‐ion batteries with high operating voltages.
Prognosis and long‐term outcomes in type I cryoglobulinemia: A multicenter study of 168 patients
Authors: Ghembaza Amine , Boleto Gonçalo , Bommelaer Marin , Karras Alexandre , Javaugue Vincent , Bridoux Frank , Alyanakian Marie‐Alexandra , Molinier Frenkel Valérie , Ghillani‐Dalbin Pascale , Musset Lucile , Barete Stéphane , Roosweil Damien , Choquet Sylvain , Le Joncour Alexandre , Mirouse Adrien , Lipsker Dan , Faguer Stanislas , Vieira Matheus , Cacoub Patrice , Biard Lucie , Saadoun David ,   from the French Cryoglobulinemia Network
Published: May 2023

AbstractType I cryoglobulinemia (CG) accounts for 10%–15% of all cryoglobulinemias and are exclusively seen in clonal proliferative hematologic conditions. In this multicenter nationwide cohort study, we analyzed the prognosis and long‐term outcomes of 168 patients with type I CG (93 (55.4%) IgM and 75 [44.6%] IgG). Five‐ and 10‐year event‐free survivals (EFS) were 26.5% (95% CI 18.2%–38.4%) and 20.8% (95% CI 13.1%–33.1%), respectively. In multivariable analysis, factors associated with poorer EFS were renal involvement (HR: 2.42, 95% CI 1.41–4.17, p = .001) and IgG type I CG (HR: 1.96, 95% CI 1.13–3.33, p = 0.016), regardless of underlying hematological disorders. IgG type I CG patients had higher cumulative incidence of relapse (94.6% [95% CI 57.8%–99.4%] vs. 56.6% [95% CI 36.6%–72.4%], p = .0002) and death at 10 years (35.8% [19.8%–64.6%] vs. 71.3% [54.0%–94.2%], p = .01) as compared to IgM CG, respectively. Overall, complete response of type I CG at 6 months was 38.7%, with no significant difference between Igs isotypes. In conclusion, renal involvement and IgG CG were identified as independent poor prognostic factors of type I CG.
Craniofacial and dental characteristics of three Japanese individuals with genetically diagnosed SATB2‐associated syndrome
Authors: Kurosaka Hiroshi , Yamamoto Sayuri , Hirasawa Kyoko , Yanagishita Tomoe , Fujioka Kaoru , Yagasaki Hideaki , Nagata Miho , Ishihara Yasuki , Yonei Ayumi , Asano Yoshihiro , Nagata Namiki , Tsujimoto Takayuki , Inubushi Toshihiro , Yamamoto Toshiyuki , Sakai Norio , Yamashiro Takashi 
Published: May 2023

AbstractCraniofacial defects are one of the most frequent phenotypes in syndromic diseases. More than 30% of syndromic diseases are associated with craniofacial defects, which are important for the precise diagnosis of systemic diseases. Special AT‐rich sequence‐binding protein 2 (SATB2)‐associated syndrome (SAS) is a rare syndromic disease associated with a wide variety of phenotypes, including intellectual disability and craniofacial defects. Among them, dental anomalies are the most frequently observed phenotype and thus becomes an important diagnostic criterion for SAS. In this report, we demonstrate three Japanese cases of genetically diagnosed SAS with detailed craniofacial phenotypes. The cases showed multiple dental problems, which have been previously reported to be linked to SAS, including abnormal crown morphologies and pulp stones. One case showed a characteristic enamel pearl at the root furcation. These phenotypes add new insights for differentiating SAS from other disorders.
The superiority and feasibility of 2,3,5‐triphenyltetrazolium chloride–stained brain tissues for molecular biology experiments based on microglial properties
Authors: Wang Yajuan , Zhang Qingrong , Zhang Shuchi , Qi Jiangtao , Li Li 
Published: May 2023

AbstractBackgroundTTC (2,3,5‐triphenyltetrazolium chloride) staining is the most commonly used method in identifying and assessing cerebral infarct volumes in the transient middle cerebral artery occlusion model. Given that microglia exhibit different morphologies in different regions after ischemic stroke, we demonstrate the superiority and necessity of using TTC‐stained brain tissue to analyze the expression of various proteins or genes in different regions based on microglia character.MethodsWe compared brain tissue (left for 10 min on ice) from the improved TTC staining method with penumbra from the traditional sampling method. We identified the feasibility and necessity of the improved staining method using real time (RT)‐PCR, Western blot, and immunofluorescence analysis.ResultsThere was no protein and RNA degradation in the TTC‐stained brain tissue group. However, the TREM2 specifically expressed on the microglia showed a significant difference between two groups in the penumbra region.ConclusionsTTC‐stained brain tissue can be used for molecular biology experiments without any restrictions. In addition, TTC‐stained brain tissue shows greater superiority due to its precise positioning.
Methane Carboxylation Using Electrochemically Activated Carbon Dioxide
Authors: Yuan Yucheng , Zhang Yuhan , Li Haoyi , Fei Muchun , Zhang Hongna , Santoro John , Wang Dunwei 
Published: May 2023

AbstractDirect synthesis of CH3COOH from CH4 and CO2 is an appealing approach for the utilization of two potent greenhouse gases that are notoriously difficult to activate. In this Communication, we report an integrated route to enable this reaction. Recognizing the thermodynamic stability of CO2, our strategy sought to first activate CO2 to produce CO (through electrochemical CO2 reduction) and O2 (through water oxidation), followed by oxidative CH4 carbonylation catalyzed by Rh single atom catalysts supported on zeolite. The net result was CH4 carboxylation with 100 % atom economy. CH3COOH was obtained at a high selectivity (>80 %) and good yield (ca. 3.2 mmol g−1cat in 3 h). Isotope labelling experiments confirmed that CH3COOH is produced through the coupling of CH4 and CO2. This work represents the first successful integration of CO/O2 production with oxidative carbonylation reaction. The result is expected to inspire more carboxylation reactions utilizing preactivated CO2 that take advantage of both products from the reduction and oxidation processes, thus achieving high atom efficiency in the synthesis.
Preparation of modified hydroxyapatite and its effect on natural latex film
Authors: Gong He , Zhong Kai , Chen Fanfan , Yi Mingyuan , Wan Lihong , Wang Zhifen , Liao Jianhe 
Published: May 2023

AbstractTo effectively screen pathogens or eliminate allergy symptoms caused by the protein in natural latex products, the strength of the natural latex film must be improved and the water‐soluble protein content in the latex products must be reduced. In this article, response surface methodology was used to optimize the reaction conditions for the preparation of hydroxyapatite (HA), and the reinforcement and adsorption of water‐soluble proteins on natural rubber latex (NRL) by HA modified by coupling agent KH550 were studied. Modified HA was homogenously dispersed in the NRL, and the tensile and tear strengths of the rubber film were increased by 37.45% and 40.86%, respectively. In addition, modified HA adsorbs the water‐soluble protein from the latex film. Compared with pure NR film, its protein content is reduced by 50.79%. This article has a reference value for the preparation of high‐performance natural latex film with low protein content.
Effect of adduct synthesis parameters on the ethylene polymerization kinetics of Ziegler Natta catalysts
Authors: Nouri‐Ahangarani Farshid , Bahri‐Laleh Naeimeh , Abedini Hossein , Nekoomanesh Mehdi 
Published: May 2023

AbstractHere, it is aimed to clarify the structure‐performance relationship in MgCl2 based Ziegler Natta catalysts toward ethylene polymerizations. In this regard, 11 different adduct precursors were prepared through industrially appreciated melt quenching method employing various: (i) reaction times for dissolving magnesium chloride inside ethanol; (ii) ethanol/MgCl2 molar ratios in the feed; (iii) heating rates during thermal dealcoholation; (iv) N2 flows during thermal dealcoholation and (v) alcohol content after thermal dealcoholation. Among the studied parameters, heating rate and N2 flow during thermal dealcoholation have the most pronounced effect on the porosity and particle size of the resulted adducts. Related Ziegler Natta catalysts were subsequently employed in ethylene polymerizations. According to the kinetic curves, catalyst productivity and form of kinetic curve (as decay or build‐up type) can be precisely tailored by proper choosing of the mentioned variables during adduct synthesis. Microstructure analysis of the prepared polyethylenes reveals that alcohol content in the final adduct has the most significant effect on the H2 response, in terms of molar mass and its distribution, of the related Ziegler Natta catalysts. The overall results help polyethylene producers in choosing proper reaction conditions during adduct synthesis for the production of different polymer grades, when productivity or H2 response is targeted.
Experimental design for combined abatement of organic compounds present in urine
Authors: Tonhela Marquele Amorim , Vernillo Natalia , Cardoso Laura Rezende , Almeida Maria Emília Veloso , Malpass Ana Claudia Granato , Malpass Geoffroy Roger Pointer 
Published: May 2023

AbstractOrganic compounds contained in urine, such as urea and creatinine, can compete with pharmaceuticals for the electro‐generated oxidants during electrochemical treatment. In addition, urine has a large amount of chloride ions, creating opportunities to produce chlorine and aqueous‐free chlorine species via electrolysis. The aim of the present study is to analyze artificial urine as a supporting electrolyte, while studying the removal of the organic components present (urea and creatinine) by employing an experimental design approach. A 2³ factorial design was employed to evaluate the efficiency of the photo‐assisted sonoelectrochemical (EC/UV/US) process. Operating conditions were optimized using response surface methodology (MRS), namely: 11.44 mL min−1 flow, 1.940 A at 160 min. The pH was analyzed and a predominance of HOCl (pH < 7.0) can be observed. Response surface methodology was used to investigate the effects and interactions of flow rate, time, and current to track the removal efficiency of organic compounds contained in artificial urine (TOC, creatinine, and urea). Over prolonged electrolysis, the EC/US/UV process achieved removal of TOC (25.7%), creatinine (68.2%), and urea (33.3%), due to the large contribution of highly reactive radical species (•OH, •Cl, ClO−).
Finite‐time dissipative control for semi‐Markovian jump systems with time‐varying delays and generally uncertain transition rates
Authors: Wan Zijing , Zhu Quanxin 
Published: May 2023

AbstractIn this paper, we mainly address the issue of finite‐time stochastic boundedness (FTSB) and finite‐time stochastic dissipation for semi‐Markovian jump systems (SMJSs) with generally uncertain transition rates (TRs). Firstly, by resorting to linear matrix inequities (LMIs), some sufficient conditions on FTSB for SMJSs with uncertain TRs are introduced, which includes two cases. Then, dissipative control is developed and a state feedback controller is designed to ensure the FTSB of the closed‐loop system by solving a series of LMIs. Finally, two examples are used to illustrate the results.