bluuebunny/crossref_metadata_2025_split huggingface dataset:
Deforestation Drivers Across the Tropics and Their Impacts on Carbon Stocks and Ecosystem Services
Authors: Seydewitz Tobias , Pradhan Prajal , Landholm David M. , Kropp Juergen P. 
Published: April 2023

AbstractGlobally, deforestation produces anthropogenic greenhouse gas (GHG) emissions, contributing substantially to climate change. Forest cover changes also have large impacts on ecosystem services. Deforestation is the dominant type of land cover change in tropical regions, and this land cover change relates to distinct causes recognized as direct deforestation drivers. Understanding these drivers requires a significant effort. Further, GHG emissions due to deforestation are quantified only in terms of biomass removal, while linking emissions from soil organic carbon (SOC) loss to deforestation is lacking. A closer picture of associated ecosystem service changes due to deforestation is also needed. We analyze for 2001–2010: (1) the magnitudes of deforestation drivers, (2) the related carbon loss, and (3) the ecosystem service value change. On the global scale, agriculture (90.3%) is the primary deforestation driver, where grassland expansion contributed the most (37.5%). The deforestation drivers differ in magnitude and spatial distribution on the continental scale. The total carbon loss by biomass removal and SOC loss accounted for 8797 Mt C and 1185 Mt C, respectively. Furthermore, tropical deforestation caused the ESV loss of 408 billion Int.$ year$$^{-1}$$

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, while the resulting land cover has the ESV of 345 billion Int.$ year$$^{-1}$$

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. Our findings highlight that agriculture substantially contributes to global carbon loss and ecosystem service loss due to deforestation. The deforestation drivers differ in magnitude and distribution for different continents. Further, we highlight the danger of putting a monetary value on nature.
Development and Psychometric Properties of Decision-Making Scale for Emergency Hospital Evacuation in Disasters
Authors: Yaghoubi Tahereh , Ardalan Ali , Ebadi Abbas , Nejati Amir , Khankeh Hamidreza , Safarpour Hamid , Khorasani-Zavareh Davoud 
Published: April 2023

AbstractBackground:The evidence shows that the need for emergency evacuation in hospitals has arisen. Designing an emergency evacuation decision making tool increases the confidence of hospital managers in the decision made. Therefore, this study was aimed at the development, and the psychometric properties, of the decision-making scale for emergency hospital evacuation in disasters.Methods:This study was done in 2 phases of qualitative study and literature review and designing and psychometric properties of the instrument. After development of the primary item pool, the psychometric properties of the questionnaire were evaluated. In this regard, face and content validity, internal consistency (Alpha’s Cronbach), reliability (ICC), and stability were assessed.Results:In the validity stage of the instrument, 4 items were removed. Also, 4 items were modified and 2 items were merged. The number of items was thus decreased to 64. After CVI calculation, 5 items were removed, 4 items were modified, and 2 items were merged. As a result of this, the number of items decreased to 58 items. The scale has good reliability and stability.Conclusion:It seems that the instrument could be useful in decision-making for emergency hospital evacuation in disasters.
Mitigation of Long-Term Risks and the Role of Insurance: A Behavioural Law and Economics Perspective
Authors: He Qihao , Faure Michael 
Published: April 2023

AbstractIn a world of rising long-term risks and their ensuing syndromes, the mitigation and financing of long-term risks are therefore arguably some of the most critical issues facing society. However, long-term thinking involving future generations draws limited attention in current political and social systems. Private insurance has received increased attention due to its expert role in risk management and its risk transfer mechanisms, and it has played an important role in dealing with some types of long-term risk, such as floods and earthquakes. Increasingly, insurance also contributes to disaster mitigation through regulating the conduct of policyholders by creating incentives for policyholders to counter short-termism and invest in reduction measures regarding long-term risks. In addition, it has been shown that supply-side problems and behavioural anomalies make it difficult to insure against long-term risks. Innovative long-term insurance solutions and a combination of public and private partnerships are proposed to overcome these restrictions.
Disorganized Political Violence: A Demonstration Case of Temperature and Insurgency
Authors: Shaver Andrew , Bollfrass Alexander K. 
Published: April 2023

AbstractAny act of battlefield violence results from a combination of organizational strategy and a combatant's personal motives. To measure the relative contribution of each, our research design leverages the predictable effect of ambient temperature on human aggression. Using fine-grained data collected by US forces during the Afghanistan and Iraq conflicts, we test whether temperature and violence are linked for attacks that can be initiated by individual combatants, but not for those requiring organizational coordination. To distinguish alternative explanations involving temperature effects on target movements, we examine situations where targets are stationary. We find that when individual combatants have discretion over the initiation of violence, ambient temperature does shape battlefield outcomes. There is no such effect when organizational coordination is necessary. We also find that ambient temperature affects combat-age males’ endorsement of insurgent violence in a survey taken during the conflict in Iraq. Our findings caution against attributing strategic causes to violence and encourage research into how strategic and individual-level motivations interact in conflict.
Taiwanese Public Opinion on the Chinese and US Military Presence in the Taiwan Strait
Authors: Wu Wen-Chin , Sun Mao-Chia , Fu Wen-Cheng , Huang Wen-Jian 
Published: April 2023

AbstractSince 2016, China has been conducting military flybys around Taiwan, while the US has approved arms sales to Taiwan on several occasions and sent warplanes and battleships through the Taiwan Strait. How does Taiwanese public opinion respond to the Chinese and US military presence in the Strait? Is the public likely to become less supportive of de jure independence for Taiwan on account of China's military deterrence or more supportive owing to a perceived likelihood of US military assistance? In this report, we provide answers to these questions based on evidence from a survey experiment conducted in Taiwan in October–November 2020. We find that Taiwanese are less sensitive to the Chinese military presence in the Taiwan Strait but have become more supportive of de jure independence after seeing the US aircraft in the area. Our findings contribute to studies of cross-Strait relations and US foreign policy on the Taiwan Strait.
Role of latent tuberculosis infection on elevated risk of cardiovascular disease: a population-based cohort study of immigrants in British Columbia, Canada, 1985–2019
Authors: Hossain Md. Belal , Johnston James C. , Cook Victoria J. , Sadatsafavi Mohsen , Wong Hubert , Romanowski Kamila , Karim Mohammad Ehsanul 
Published: April 2023

Abstract
We investigated cardiovascular disease (CVD) risk associated with latent tuberculosis infection (LTBI) (Aim-1) and LTBI therapy (Aim-2) in British Columbia, a low-tuberculosis-incidence setting. 49,197 participants had valid LTBI test results. Cox proportional hazards model was fitted, adjusting for potential confounders. Compared with the participants who tested LTBI negative, LTBI positive was associated with an 8% higher CVD risk in complete case data (adjusted hazard ratio (HR): 1.08, 95% CI: 0.99-1.18), a statistically significant 11% higher risk when missing confounder values were imputed using multiple imputation (HR: 1.11, 95% CI: 1.02-1.20), and 10% higher risk when additional proxy variables supplementing known unmeasured confounders were incorporated in the highdimensional disease risk score technique to reduce residual confounding (HR: 1.10, 95% CI: 1.01-1.20). Also, compared with participants who tested negative, CVD risk was 27% higher among people who were LTBI positive but incomplete LTBI therapy (HR: 1.27, 95% CI: 1.04-1.55), whereas the risk was similar in people who completed LTBI therapy (HR: 1.04, 95% CI: 0.87-1.24). Findings were consistent in different sensitivity analyses. We concluded that LTBI is associated with an increased CVD risk in low-tuberculosis-incidence settings, with a higher risk associated with incomplete LTBI therapy and attenuated risk when therapy is completed.
Detonating the air: The legality of the use of thermobaric weapons under international humanitarian law
Authors: van Coller Arthur 
Published: April 2023

AbstractThermobaric weapons cause damage and harm through overpressure and thermal effects, but secondary harm may also occur due to fragmentation, the consumption and depletion of ambient oxygen, and the release of toxic gases and smoke. Several international instruments prohibit or regulate weapons that generate asphyxiating or toxic gases, poison or poisoned weapons, chemical weapons, and weapons primarily designed to be incendiary. Thermobaric weapons are, however, primarily designed for blast and are not specifically covered by, or excluded from, the application of these instruments. The general customary law principles of international humanitarian law that determine the legality of the use of all weapons, including thermobaric weapons, prohibit causing superfluous injury and unnecessary suffering, and the use of indiscriminate weapons. Thermobaric weapons cause severe suffering but will not be rendered unlawful merely because of this effect. These weapons are also not automatically and inherently indiscriminate when used in their normal or designed circumstances. The use of thermobaric weapons, when directed at a military objective, while considering all feasible precautions to protect civilians and civilian objects and the principle of proportionality, will, as a result, be lawful in most circumstances. However, the use of thermobaric weapons should, in a similar manner to heavy explosive weapons, be avoided in urban or populated areas.
A Localized and Surprising Source of Energetic Ions in the Uranian Magnetosphere Between Miranda and Ariel
Authors: Cohen Ian J. , Turner Drew L. , Kollmann Peter , Clark George B. , Hill Matthew E. , Regoli Leonardo H. , Gershman Daniel J. 
Published: April 2023

AbstractIn situ exploration of Uranus has been limited to a single flyby encounter by the Voyager 2 spacecraft in January 1986. Nonetheless, new investigation has led to significant questions about the origin of energetic ions observed in the region between its moons Miranda and Ariel. Radial and pitch angle diffusion modeling suggests that typical magnetospheric sources cannot explain the observed characteristics of these energetic ions. We suggest that these are likely being introduced by a source from one of these moons and give rise to waves that could result in the observed particle distribution characteristics. This may reveal that internal plasma sources in the system may be important for Uranus' magnetospheric dynamics and may contribute to its unexpectedly strong radiation belts.
Climatologies of Various OH Lines From About 90,000 X‐Shooter Spectra
Authors: Noll S. , Schmidt C. , Kausch W. , Bittner M. , Kimeswenger S. 
Published: April 2023

AbstractThe nocturnal mesopause region of the Earth's atmosphere radiates chemiluminescent emission from various roto‐vibrational bands of hydroxyl (OH), which is therefore a good tracer of the chemistry and dynamics at the emission altitudes. Intensity variations can, for example, be caused by the general circulation, gravity waves, tides, planetary waves, and the solar activity. While the basic OH response to the different dynamical influences has been studied quite frequently, detailed comparisons of the various individual lines are still rare. Such studies can improve our understanding of the OH‐related variations as each line shows a different emission profile. We have therefore used about 90,000 spectra of the X‐shooter spectrograph of the Very Large Telescope at Cerro Paranal in Chile in order to study 10 years of variations of 298 OH lines. The analysis focuses on climatologies of intensity, solar cycle effect (SCE), and residual variability (especially with respect to time scales of hours and about 2 days) for day of year and local time. For a better understanding of the resulting variability patterns and the line‐specific differences, we applied decomposition techniques, studied the variability depending on time scale, and calculated correlations. As a result, the mixing of thermalized and nonthermalized OH level populations clearly influences the amplitude of the variations. Moreover, the local times of the variability features shift depending on the effective line emission height, which can mainly be explained by the propagation of the migrating diurnal tide. This behavior also contributes to remarkable differences in the effective SCE.
Present‐Day Caribbean‐North American Oblique Convergence Through the Ocoa‐Bonao‐La Guacara Fault Zone, Southern Central Hispaniola: A Transition Zone Between Oceanic Subduction and Arc‐Oceanic Plateau Collision
Authors: Escuder‐Viruete J. , Fernández F. J. , Valera F. Pérez , Medialdea A. 
Published: April 2023

AbstractAccording to GPS measurements, the Caribbean plate is moving east‐northeastward relative to the North American plate at a rate of ∼20 mm/a. This oblique motion is partly accommodated in southern Hispaniola by northward underthrusting/subduction bellow the Muertos submerged accretionary prism and the Peralta fold‐and‐thrust belt. This work investigates the active transition zone that connects Muertos and Peralta: the Ocoa‐Bonao‐La Guacara fault zone (OBFZ). Combined detailed structural analysis at macroscopic and mesoscopic scales, regional magnetic data and seismicity analysis, geomorphic observations, fault‐slip data inversion and geochronology of Quaternary deposits allow to establish the deformation pattern for the OBFZ along southern central Hispaniola. Distinct tectonic regimes have occurred successively in the Neogene, within a consistent regional NE‐trending horizontal shortening: (a) a lower Miocene to Early Pleistocene D1 regime characterized by SW‐directed thrusting that homogeneously affects the region; and (b) an Early/Middle Pleistocene to Holocene D2 regime of strike‐slip to transpressional faulting mainly located along the OBFZ. The change is coeval with the tectonic indentation of the Beata Ridge in the back‐arc region of the Hispaniola microplate. Finally, a Late Pleistocene to Holocene D3 extensional regime has a local development around the Ocoa Bay. Part of the present‐day stress‐field induced by the Beata Ridge collision is accommodated by the OBFZ within the Hispaniola microplate. This fault zone defines the onland transition between oceanic subduction and arc‐oceanic plateau collision. Due to its length and potential to generate large earthquakes, the OBFZ must be considered in the regional seismic hazard assessment.
Characterizing the Final Stage of Simulated Earthquake Nucleation Governed by Rate‐And‐State Fault Friction
Authors: He Changrong , Zhang Lei , Liu Peixun , Chen Qi‐Fu 
Published: April 2023

AbstractPrevious experiments and modeling on earthquake nucleation reveal accelerating slip and development of a final patch of fixed or expanding length, but whether the nucleation phase is spatially large enough to be detected in real‐Earth conditions with durations long enough to be helpful is unknown. This study performed a suit of simulations of the nucleation process based on the rate‐and‐state friction law on homogeneous faults started from a “locked” state. Our results reveal the development of a weakening‐zone core (WZcore, defined as a region bounded by two outwardly moving shoulders of stress distribution during the early phase, and later bounded by two inwardly shifting edges between the stress‐releasing region and stress‐increasing exterior) where stress releases continuously, which expands first to a dimension less than the half fault length then shrinks to a final length before re‐expanding. The slip rate within the WZcore is above several times of the driving rate, and the high‐rate region expands constantly up to the instability. The WZcore is similar to a strain‐releasing zone in our new experiment. Under the assumption that much higher seismicity rate can be observed within the WZcore due to higher slip rate and stress‐releasing state as augmented driving force for small asperities, these nucleation features, as well as the slip rate levels in our model, are consistent with step‐like increases in seismicity preceding large subduction earthquakes. On the time scale, duration of the WZcore is weeks before large subduction earthquakes under high driving rate, but years on low‐rate continental faults.
Benzo[a]pyrene stress impacts adaptive strategies and ecological functions of earthworm intestinal viromes
Authors: Xia Rong , Sun Mingming , Balcázar José Luis , Yu Pingfeng , Hu Feng , Alvarez Pedro J J 
Published: April 2023

Abstract
The earthworm gut virome influences the structure and function of the gut microbiome, which in turn influences worm health and ecological functions. However, despite its ecological and soil quality implications, it remains elusive how earthworm intestinal phages respond to different environmental stress, such as soil pollution. Here we used metagenomics and metatranscriptomics to investigate interactions between the worm intestinal phages and their bacteria under different benzo[a]pyrene (BaP) concentrations. Low-level BaP (0.1 mg kg−1) stress stimulated microbial metabolism (1.74-fold to control), and enhanced the antiphage defense system (n = 75) against infection (8 phage-host pairs). Low-level BaP exposure resulted in the highest proportion of lysogenic phages (88%), and prophages expressed auxiliary metabolic genes (AMGs) associated with nutrient transformation (e.g., amino acid metabolism). In contrast, high-level BaP exposure (200 mg kg−1) disrupted microbial metabolism and suppressed the antiphage systems (n = 29), leading to the increase in phage-bacterium association (37 phage-host pairs) and conversion of lysogenic to lytic phages (lysogenic ratio declined to 43%). Despite fluctuating phage-bacterium interactions, phage-encoded AMGs related to microbial antioxidant and pollutant degradation were enriched, apparently to alleviate pollution stress. Overall, these findings expand our knowledge of complex phage-bacterium interactions in pollution-stressed worm guts, and deepen our understanding of the ecological and evolutionary roles of phages.
Halide Perovskite glues activate two-dimensional covalent organic framework crystallites for selective NO2 sensing
Authors: Ye Wen , Zhao Liangdan , Lin Hong-Zhen , Ding Lifeng , Cao Qiang , Chen Ze-Kun , Wang Jia , Sun Qi-Meng , He Jing-Hui , Lu Jian-Mei 
Published: April 2023

AbstractTwo-dimensional covalent organic frameworks (2D COFs) are promising for gas sensing owing to the large surface area, abundant active sites, and their semiconducting nature. However, 2D COFs are usually produced in the form of insoluble micro-crystallites. Their poor contacts between grain boundaries severely suppress the conductivity, which are too low for chemresistive gas sensing. Here, we demonstrate that halide perovskites can be employed as electric glues to bond 2D COF crystallites to improve their conductivity by two orders of magnitude, activating them to detect NO2 with high selectivity and sensitivity. Resonant microcantilever, grand canonical Monte Carlo, density functional theory and sum-frequency generation analyses prove that 2D COFs can enrich and transfer electrons to NO2 molecules, leading to increased device conductivity. This work provides a facile approach for improving the conductivity of polycrystalline 2D COF films and may expand their applications in semiconductor devices, such as sensors, resistors, memristors and field-emission transistors.
Central cavity dehydration as a gating mechanism of potassium channels
Authors: Gu Ruo-Xu , de Groot Bert L. 
Published: April 2023

Abstract
The hydrophobic gating model, in which ion permeation is inhibited by the hydrophobicity, rather than a physical occlusion of the nanopore, functions in various ion channels including potassium channels. Available research focused on the energy barriers for ion/water conduction due to the hydrophobicity, whereas how hydrophobic gating affects the function and structure of channels remains unclear. Here, we use potassium channels as examples and conduct molecular dynamics simulations to investigate this problem. Our simulations find channel activities (ion currents) highly correlated with cavity hydration level, implying insufficient hydration as a barrier for ion permeation. Enforced cavity dehydration successfully induces conformational transitions between known channel states, further implying cavity dewetting as a key step in the gating procedure of potassium channels utilizing different activation mechanisms. Our work reveals how the cavity dewetting is coupled to structural changes of potassium channels and how it affects channel activity. The conclusion may also apply to other ion channels.
Hsp90 provides a platform for kinase dephosphorylation by PP5
Authors: Jaime-Garza Maru , Nowotny Carlos A. , Coutandin Daniel , Wang Feng , Tabios Mariano , Agard David A. 
Published: April 2023

AbstractThe Hsp90 molecular chaperone collaborates with the phosphorylated Cdc37 cochaperone for the folding and activation of its many client kinases. As with many kinases, the Hsp90 client kinase CRaf is activated by phosphorylation at specific regulatory sites. The cochaperone phosphatase PP5 dephosphorylates CRaf and Cdc37 in an Hsp90-dependent manner. Although dephosphorylating Cdc37 has been proposed as a mechanism for releasing Hsp90-bound kinases, here we show that Hsp90 bound kinases sterically inhibit Cdc37 dephosphorylation indicating kinase release must occur before Cdc37 dephosphorylation. Our cryo-EM structure of PP5 in complex with Hsp90:Cdc37:CRaf reveals how Hsp90 both activates PP5 and scaffolds its association with the bound CRaf to dephosphorylate phosphorylation sites neighboring the kinase domain. Thus, we directly show how Hsp90’s role in maintaining protein homeostasis goes beyond folding and activation to include post translationally modifying its client kinases.
The melanocortin action is biased toward protection from weight loss in mice
Authors: Li Hongli , Xu Yuanzhong , Jiang Yanyan , Jiang Zhiying , Otiz-Guzman Joshua , Morrill Jessie C. , Cai Jing , Mao Zhengmei , Xu Yong , Arenkiel Benjamin R. , Huang Cheng , Tong Qingchun 
Published: April 2023

AbstractThe melanocortin action is well perceived for its ability to regulate body weight bidirectionally with its gain of function reducing body weight and loss of function promoting obesity. However, this notion cannot explain the difficulty in identifying effective therapeutics toward treating general obesity via activation of the melanocortin action. Here, we provide evidence that altered melanocortin action is only able to cause one-directional obesity development. We demonstrate that chronic inhibition of arcuate neurons expressing proopiomelanocortin (POMC) or paraventricular hypothalamic neurons expressing melanocortin receptor 4 (MC4R) causes massive obesity. However, chronic activation of these neuronal populations failed to reduce body weight. Furthermore, gain of function of the melanocortin action through overexpression of MC4R, POMC or its derived peptides had little effect on obesity prevention or reversal. These results reveal a bias of the melanocortin action towards protection of weight loss and provide a neural basis behind the well-known, but mechanistically ill-defined, predisposition to obesity development.