bluuebunny/crossref_metadata_2025_split huggingface dataset:
Foreseeing everyday life for older postoperative patients with gastrointestinal cancer: a constructivist grounded theory
Authors: Horibe Mitsuhiro 
Published: March 2023

Background: With the rapid ageing of societies worldwide, the number of older individuals diagnosed with gastrointestinal cancer is expected to increase. Aims: This study aimed to describe nursing practices foreseeing everyday life after discharge in older patients following resection for gastrointestinal cancer. Methods: Data were collected using participant observation and semi-structured interviews and analysed using Charmaz's grounded theory method. Categories and subcategories were constructed using theoretical sampling until theoretical sufficiency was reached. Findings: Overall, 19 nurses (16 women and three men) and two patients (one man in his 80s and one woman in her 70s) were included. The following three categories were constructed: ‘establishing everyday foundation,’ ‘maintaining the rhythm,’ and ‘foreseeing a new everyday life,’ which were further divided into subcategories. Conclusion: The nursing practice identified here describes the process of encouraging older patients to incorporate physical changes while maximising their independent activities following resection of gastrointestinal cancer.
Effectiveness of wound contact layers in enabling undisturbed wound management: a case series
Authors: Barrett Simon , Rippon Mark G , Rogers Alan A 
Published: March 2023

Objective: Wound contact layers (WCLs) are intended to protect and support wounds during the healing process. An open, non comparative, case series clinical evaluation was undertaken to assess the impact of these dressings on establishing an undisturbed wound environment that supports effective wound management, and to allow the establishment of limits of duration of the wear time for the experimental WCLs. Method: The primary objectives of this clinical evaluation were to assess the ability of the WCLs to prevent tissue disturbance to the wound and surrounding skin and for the clinicians to have confidence to extend the wear time of the WCL dressings. For them to have confidence in leaving the dressings in place for extended periods, the assessment of the wound and periwound skin condition and an assessment of patient comfort was performed: assessment of wound and periwound condition in relation to tissue adherence of the dressing to the wound resulting in tissue damage/bleeding (to wound and/or periwound skin) and cellular infiltration into the WCL; assessment of patient wearing comfort and satisfaction; assessment of WCL wear time, relating to times between dressing changes as judged by the clinician. Results: Based upon five parameters used to assess the extent to which the WCLs Atrauman, Atrauman Silicone and Atrauman Ag (HARTMANN, Germany) disturbed the underlying tissues—bleeding, wound tissue damage, periwound skin damage, tissue ingrowth and dressing adherence—the majority (>95%) of assessments indicated low or no disturbance of tissue. Over the 14 days of study assessment, the mean (±standard deviation) wear time was 7.3±1.2 days for the Atrauman group, 9.9±2.8 days for the Atrauman Silicone group, and 5.8±1.0 days for the Atrauman Ag group. All dressings were well tolerated by patients and rated highly in terms of in-use dressing performance. Conclusion: The results indicate that Atrauman WCLs are suitable for the management of a variety of wounds as they promote an undisturbed wound environment, including extended wear time.
Treatment of complex extremity wounds with MatriDerm: first clinical experience in the US
Authors: Hones Keegan M , Hones Jaime , Satteson Ellen S , Chim Harvey 
Published: March 2023

Objective: Coverage of upper and lower extremity wounds with exposed vital structures such as tendon and bone is reliant on pedicled and free flaps. However, a population of patients with medical comorbidities or other social issues may not be suitable for flap coverage. We present the first in patient clinical experience in the US with MatriDerm (Billerbeck, Germany) for treatment of difficult extremity wounds, all with exposed bone or tendon. Method: MatriDerm dermal matrix has been popular in Europe for coverage of wounds. However, MatriDerm only received full approval for use by the US Food and Drug Administration (FDA) in 2021. Here we review our clinical experience. Results: Locations (n=11) treated included forearm (n=1), hand (n=4), leg (n=3), and feet (n=3). Vital structures in wounds exposed included bone (n=3), bone and tendon (n=1), and tendon (n=7). Mean area of the wound treated was 59.2cm2 (range: 2 to 230). In our series, eight out of 11 wounds healed, with MatriDerm only (n=6) or following delayed skin grafting (n=2). Mean time to healing in the patients treated only with MatriDerm was 49 days (range 7 to 84). Mean time to split-thickness skin grafting in the remaining two patients was 44.5 days (range 32 to 57). Conclusion: MatriDerm has potential for treatment of complex extremity wounds, which would otherwise require flap coverage, in patients who are not good candidates for flap surgery.
Psychometric validation of the Korean Pressure Ulcer Knowledge Assessment Tool
Authors: Ryu Jung Mi , Kim Myoung Soo , Kim Jung Yoon 
Published: March 2023

Objective:The purpose of this study was to evaluate the psychometric properties, including content validity, validity of multiple choice items, and the reliability of the Korean version of the Pressure Ulcer Knowledge Assessment Tool (K-PUKAT 2.0), using classical test theory (CTT) and item response theory (IRT).Method:Linguistic validation process and factor analysis were conducted among wound care nurses, staff nurses and nursing students. Items were analysed according to the CTT and IRT using a two-parameter logistic model. Intraclass correlation coefficients were used to examine reliability.Results:A total of 378 wound care nurses, staff nurses and nursing students participated in this study. While most items showed moderate difficulty based on the CTT, difficulty index values based on the IRT were more broadly distributed (low: 5 items; moderate: 9 items; high: 1 item). The intraclass correlation coefficient for K-PUKAT 2.0 was 0.72.Conclusion:The K-PUKAT 2.0 demonstrated concise and good psychometric properties. Based on the results of this study, repetitive use of K-PUKAT 2.0 will not only help in distinguishing whether an individual has sufficient clinical knowledge, but will also play a key role in supporting learning.
Response times of a degenerately doped semiconductor based plasmonic modulator
Authors: Vinnakota Raj K. , Dong Zuoming , Briggs Andrew F. , Bank Seth R. , Wasserman Daniel , Genov Dentcho A. 
Published: March 2023

We present a transient response study of a semiconductor based plasmonic switch. The proposed device operates through active control and modulation of localized electron density waves, i.e., surface plasmon polaritons (SPPs) at degenerately doped In0.53Ga0.47As based PN++ junctions. A set of devices is designed and fabricated, and its optical and electronic behaviors are studied both experimentally and theoretically. Optical characterization shows far-field reflectivity modulation, a result of electrical tuning of the SPPs at the PN++ junctions for mid-IR wavelengths, with significant 3 dB bandwidths. Numerical studies using a self-consistent electro-optic multi-physics model are performed to uncover the temporal response of the devices’ electromagnetic and kinetic mechanisms facilitating the SPP switching at the PN++ junctions. Numerical simulations show strong synergy with the experimental results, validating the claim of potential optoelectronic switching with a 3 dB bandwidth as high as 2 GHz. Thus, this study confirms that the presented SPP diode architecture can be implemented for high-speed control of SPPs through electrical means, providing a pathway toward fast all-semiconductor plasmonic devices.
One versus two doses of ivermectin-based mass drug administration for the control of scabies: A cluster randomised non-inferiority trial
Authors: Lake Susanna J. , Engelman Daniel , Zinihite Julie , Sokana Oliver , Boara Dickson , Nasi Titus , Gorae Christina , Osti Millicent H. , Phelan Sophie , Parnaby Matthew , Grobler Anneke C. , Schuster Tibor , Andrews Ross , Whitfeld Margot J. , Marks Michael , Romani Lucia , Steer Andrew C. , Kaldor John M. 
Published: March 2023

Background
Mass drug administration (MDA) based on two doses of ivermectin, one week apart, substantially reduces prevalence of both scabies and impetigo. The Regimens of Ivermectin for Scabies Elimination (RISE) trial assessed whether one-dose ivermectin-based MDA would be as effective.

Methods
RISE was a cluster-randomised trial in Solomon Islands. We assigned 20 villages in a 1:1 ratio to one- or two-dose ivermectin-based MDA. We planned to test whether the impact of one dose on scabies prevalence at 12 and 24 months was non-inferior to two, at a 5% non-inferiority margin.

Results
We deferred endpoint assessment to 21 months due to COVID-19. We enrolled 5239 participants in 20 villages at baseline and 3369 at 21 months from an estimated population of 5500. At baseline scabies prevalence was similar in the two arms (one-dose 17·2%; two-dose 13·2%). At 21 months, there was no reduction in scabies prevalence (one-dose 18·7%; two-dose 13·4%), and the confidence interval around the difference included values substantially greater than 5%. There was however a reduction in prevalence among those who had been present at the baseline assessment (one-dose 15·9%; two-dose 10·8%). Additionally, we found a reduction in both scabies severity and impetigo prevalence in both arms, to a similar degree.

Conclusions
There was no indication of an overall decline in scabies prevalence in either arm. The reduction in scabies prevalence in those present at baseline suggests that the unexpectedly high influx of people into the trial villages, likely related to the COVID-19 pandemic, may have compromised the effectiveness of the MDA. Despite the lack of effect there are important lessons to be learnt from this trial about conducting MDA for scabies in high prevalence settings.

Trial registration
Registered with Australian New Zealand Clinical Trials Registry ACTRN12618001086257.
Which clinical research questions are the most important? Development and preliminary validation of the Australia & New Zealand Musculoskeletal (ANZMUSC) Clinical Trials Network Research Question Importance Tool (ANZMUSC-RQIT)
Authors: Taylor William J. , Willink Robin , O’Connor Denise A. , Patel Vinay , Bourne Allison , Harris Ian A. , Whittle Samuel L. , Richards Bethan , Clavisi Ornella , Green Sally , Hinman Rana S. , Maher Chris G. , Cahill Ainslie , McPherson Annie , Hewson Charlotte , May Suzie E. , Walker Bruce , Robinson Philip C. , Ghersi Davina , Fitzpatrick Jane , Winzenberg Tania , Fallon Kieran , Glasziou Paul , Billot Laurent , Buchbinder Rachelle 
Published: March 2023

Background and aims
High quality clinical research that addresses important questions requires significant resources. In resource-constrained environments, projects will therefore need to be prioritized. The Australia and New Zealand Musculoskeletal (ANZMUSC) Clinical Trials Network aimed to develop a stakeholder-based, transparent, easily implementable tool that provides a score for the ‘importance’ of a research question which could be used to rank research projects in order of importance.

Methods
Using a mixed-methods, multi-stage approach that included a Delphi survey, consensus workshop, inter-rater reliability testing, validity testing and calibration using a discrete-choice methodology, the Research Question Importance Tool (ANZMUSC-RQIT) was developed. The tool incorporated broad stakeholder opinion, including consumers, at each stage and is designed for scoring by committee consensus.

Results
The ANZMUSC-RQIT tool consists of 5 dimensions (compared to 6 dimensions for an earlier version of RQIT): (1) extent of stakeholder consensus, (2) social burden of health condition, (3) patient burden of health condition, (4) anticipated effectiveness of proposed intervention, and (5) extent to which health equity is addressed by the research. Each dimension is assessed by defining ordered levels of a relevant attribute and by assigning a score to each level. The scores for the dimensions are then summed to obtain an overall ANZMUSC-RQIT score, which represents the importance of the research question. The result is a score on an interval scale with an arbitrary unit, ranging from 0 (minimal importance) to 1000. The ANZMUSC-RQIT dimensions can be reliably ordered by committee consensus (ICC 0.73–0.93) and the overall score is positively associated with citation count (standardised regression coefficient 0.33, p<0.001) and journal impact factor group (OR 6.78, 95% CI 3.17 to 14.50 for 3rd tertile compared to 1st tertile of ANZMUSC-RQIT scores) for 200 published musculoskeletal clinical trials.

Conclusion
We propose that the ANZMUSC-RQIT is a useful tool for prioritising the importance of a research question.
Psychometric properties of an innovative smartphone application to investigate the daily impact of hypoglycemia in people with type 1 or type 2 diabetes: The Hypo-METRICS app
Authors: Søholm Uffe , Broadley Melanie , Zaremba Natalie , Divilly Patrick , Nefs Giesje , Carlton Jill , Mader Julia K. , Baumann Petra Martina , Gomes Mikel , Martine-Edith Gilberte , Pollard Daniel J. , Rath Dajana , Heller Simon , Pedersen-Bjergaard Ulrik , McCrimmon Rory J. , Renard Eric , Evans Mark , de Galan Bastiaan , Forkmann Thomas , Amiel Stephanie A. , Hendrieckx Christel , Speight Jane , Choudhary Pratik , Pouwer Frans ,   on behalf of the Hypo-RESOLVE consortium
Published: March 2023

IntroductionThe aim of this study was to determine the acceptability and psychometric properties of the Hypo-METRICS (Hypoglycemia MEasurement, ThResholds and ImpaCtS) application (app): a novel tool designed to assess the direct impact of symptomatic and asymptomatic hypoglycemia on daily functioning in people with insulin-treated diabetes.Materials and methods100 adults with type 1 diabetes mellitus (T1DM, n = 64) or insulin-treated type 2 diabetes mellitus (T2DM, n = 36) completed three daily ‘check-ins’ (morning, afternoon and evening) via the Hypo-METRICs app across 10 weeks, to respond to 29 unique questions about their subjective daily functioning. Questions addressed sleep quality, energy level, mood, affect, cognitive functioning, fear of hypoglycemia and hyperglycemia, social functioning, and work/productivity. Completion rates, structural validity, internal consistency, and test-retest reliability were explored. App responses were correlated with validated person-reported outcome measures to investigate convergent (rs>±0.3) and divergent (rs<±0.3) validity.ResultsParticipants’ mean±SD age was 54±16 years, diabetes duration was 23±13 years, and most recent HbA1c was 56.6±9.8 mmol/mol. Participants submitted mean±SD 191±16 out of 210 possible ‘check-ins’ (91%). Structural validity was confirmed with multi-level confirmatory factor analysis showing good model fit on the adjusted model (Comparative Fit Index >0.95, Root-Mean-Square Error of Approximation <0.06, Standardized Root-Mean-square Residual<0.08). Scales had satisfactory internal consistency (all ω≥0.5), and high test-retest reliability (rs≥0.7). Convergent and divergent validity were demonstrated for most scales.ConclusionHigh completion rates and satisfactory psychometric properties demonstrated that the Hypo-METRICS app is acceptable to adults with T1DM and T2DM, and a reliable and valid tool to explore the daily impact of hypoglycemia.
Balloon Occlusion and Pharmomechanical Thrombectomy utilizing the CleanerXT/Cleaner15 Thrombectomy System
Authors: Stibbs Peter , Davis Cliff , Patel Jogi 
Published: March 2023

Use of the CleanerXT/Cleaner thrombectomy device (Argon Medical Devices, Plano,Texas) has been described utilizing the placement of retrievable IVCF to prevent catastrophic embolization of macerated thrombus which could result in symptomatic pulmonary embolism as a complication to mechanical
thrombectomy in the lower extremity vasculature¹. The following
describes the performance of the thrombectomy procedure using occlusive balloon placement in the IVC, and/ or, the non thrombosed section of iliac/ femoral vein to prevent embolic migration and to allow for concentration of applied lytics within the thrombus of the effected venous structure while limiting dissolution and systemic lytic exposure.
Histomorphological study of hepatic lobules of adult Wistar rats administered with aqueous extracts of leaves of cassia singueana
Authors: Alley Jemila , Jibril Adam N. , Saleh Sagir M. , Umar Mikail , Sirajo Mujittapha U. 
Published: March 2023

Abstract

Objectives

Cassia singueana is widely used in northern Nigeria as an herb for the treatment of enamors ailments. Nevertheless the toxicity of the herb on liver architecture; the hepatic lobule and body weight is yet to be authenticated.

Methods
A total of 24 male Wistar rats with an average weight of 150 g were randomly placed into four groups. Each group consisted of 6 rats. Group A served as the control group while groups B, C and D were given 150, 300, and 450 mg of Cassia singueana leaves extract respectively for 14 days. The animals were weighed before, during and after the treatment phase subsequently, they were sacrificed and the liver tissues were processed and stained using hematoxylin and eosin (H&E) stain, Masson’s and Trichrome Stain, Gordon and Sweet’s Stain, and Periodic Acid Schiff (PAS)Stain.

Results
There was no significant change in the animal’s body weight of in all the groups when compared to the control group. Our histology result showed that Cassia singueana induced vascular lesion and hepatocytes degeneration putatively though mechanism of cell death (apoptosis and necrosis). It was also found that Cassia singueana has no toxic effect on the reticular fibers of the liver. High dose of Cassia singueana was found to induce the deposition of PAS positive materials in hepatocytes.

Conclusions

The Cassia singueana leaves extract induce hepatocyte degeneration and vascular lesion in the hepatic lobules of the wistar rats, without affecting the animals’ body weight.
A strategic review: the role of commercially available tools for planning, modelling, optimization, and performance measurement of photovoltaic systems
Authors: Khan Akhlaque Ahmad , Minai Ahmad Faiz 
Published: March 2023

Abstract
Solar power and photovoltaic (PV) systems have become crucial components of the world’s energy portfolio. The PV systems may be engineered in a number of ways, including off-grid, on-grid, and tracking. Incorporating PV systems with traditional sources of power like diesel generators (DGs) or other renewable sources, like windmills, is possible. In this situation, developers, investigators, and experts are striving to create the best design that accommodates the load demand in regards to technological, financial, ecological, and social aspects. To assist in figuring out the best PV size and design, numerous tools, models, and heuristics were created and rolled out. The majority of the tools, models, and techniques used to build PV systems over the past 70 years were described, assessed, and evaluated in this article. It was observed that methods for optimising PV system designs evolved with time and demand. Tool design is often divided into segments such as artificial and classical, solo and hybrid approaches, and others. Hybrid approaches, nevertheless, gained prominence to become the most popular approach because of its adaptability and capacity for handling challenging issues. This paper’s evaluation also helps the readers choose a PV system design tool (approximately 46) that is suited for their needs.
From narrative past to mirativity and direct evidentiality: the case of Moldavian (Csángó) Hungarian
Authors: Kiss Katalin É. 
Published: March 2023

AbstractThis paper describes the evolution of grammaticalized evidentiality in the Moldavian dialect of Hungarian. It documents how the suffix-a/e, originally the marker of narrative past, became a rare, elevated marker of past tense highlighting significant past events; how it assumed a mirative overtone; and how the features ʻwitnessedʼ and ʻimmediate pastʼ, often present in mirative utterances, became inherent parts of its meaning. This grammaticalization path has resulted in an evidential system with typologically unique features. It is a two-term system based on the opposition of direct evidentiality and no evidentiality – violating the alleged universal that if a language has grammaticalized direct evidentiality, it has also grammaticalized indirect evidentiality. Mirative meaning is expressed by the same -a/esuffix that also encodes direct evidentiality – whereas it is claimed to be the extension of inferred evidentiality elsewhere. The unique properties of Moldavian Hungarian evidentiality are derived from the historical evolution of the -a/esuffix.
Part 1: Festschrift Commentaries
Authors: Heintz Sonja 
Published: March 2023

Abstract
In this first part of the “Festschrift for Willibald Ruch”, we collated seven commentaries, from board members and attendees of the Humour Summer School, Colin Cooper, Alyona Ivanova, Martin D. Lampert, Rod A. Martin, Paul E. McGhee and Frank ‘Appletree’ Rodden.
The entropy production paradox for fractional diffusion
Authors: Hoffmann Karl Heinz , Essex Christopher , Prehl Janett , Kulmus Kathrin 
Published: March 2023

AbstractDispersive diffusion and wave propagation seem to be unconnected and fundamentally different evolution equations. In the context of anomalous diffusion however modeling approaches based on fractional diffusion equations have been presented, which allow to build a continuous bridge between the two regimes. The transition from irreversible dispersive diffusion to reversible wave propagation shows an unexpected increase in entropy production. This seemingly paradoxical behavior of fractional diffusion is reviewed and compared to the behavior of a tree-based diffusion model.
The origin and development of pragmatics as a study of meaning: semiotic perspective
Authors: Niu Min 
Published: March 2023

Abstract
Pragmatics has grown into a flourishing independent academic discipline. Undefined and unsolved are, nevertheless, such confusing and controversial concerns in its evolution as research boundaries and uncertain definition. Some academics view Austin᾽s Speech Act Theory to be the birth of pragmatics, which certainly confines pragmatics to the field of linguistics and hence limits its study scope. This assertion is incongruous with Morris’ primary objective of proposing the word pragmatics from the standpoint of semiotics, inspired by Peirce. This research intends to investigate pragmatics from the perspective of linguistic philosophy and semiotics and argues that pragmatics derives and develops from Peirce’s pragmatist semiotics and Morris’ behavioral semiotics. Pragmatics is the exertion of the “interpretant” in Pierce’s Semiotics. Clearly, it is one of the three branches of Morris’s semiotics that investigates the relationship between signs and sign users. The meaning of signs is derived from the interpretation of sign users. Pierce’s pragmatism or pragmaticism is the intellectual foundation of pragmatics. As its research objective, it focuses on the relationship between meaning and context, i.e., the illocutionary meaning not covered by the study of semantics. Its primary methodology is based on logical reasoning.