bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effectiveness of Screening in Patients with Rheumatic Disease on Biological Therapy and Risk of Active Tuberculosis
Authors: Abdulaziz Sultana , Attar Suzan , Bajhammoh Wael , Alsindi Eman , Bakhashwain Eman , Ayish Doaa , Joudah Roaa , Alhashimi Nouran , Rmdan Lmees 
Published: August 2023

Background:
Treatment with biologic therapy has been associated with a high risk of reactivation of latent tuberculosis (TB).

Aims and Objectives:
The study aimed to access the effectiveness of TB screening recommendations before the initiation of biological therapy and identify the incidence of active TB among these patients.

Materials and Methods:
A hospital-based retrospective cohort study among rheumatic disease patients on biological therapy in two centers between January 2005 to December 2019 was performed. Data was collected through review of medical records.

Results:
A total of 365 patients were included over a period of 14 years. Majority had Rheumatoid arthritis (RA) (80%). The mean age was 47.54 (±14.2), 311 (85%) were females with a mean duration of disease 8.45 years (± 6.58). Hundred forty-nine (42.3%) were on steroids. Anti TNFs were prescribed in 213 (58.4%) patients, Non-Anti-TNFs 124 (36.6%) patients, and Jak inhibitors 18 (5%) patients. TB screening was done to all patients except 3 patients (data missing) before commencing biologics. Forty-four (12.1%) patients had latent TB at baseline and all received chemoprophylaxis with isoniazid before starting biologics. Four patients with active TB were identified (one with Behcet’s disease and three with RA). One patient had a reactivation of latent TB and 3 patients developed de novo TB. Two were on rituximab and one each on infliximab and adalimumab. Two cases had pulmonary TB and two others had extrapulmonary TB (pericarditis and brain abscess each). All four patients with active TB were treated with standard anti TB medications. Three had complete resolution of their TB and one died.

Conculsion:
Baseline screening has been effectively carried out in our cohort as per recommendations. Physicians should be vigilant for symptoms and signs of active TB as not only reactivation of latent TB can occur with patients on biologics but in addition de novo TB can occur specially in endemic areas.

Funding:
None
Effect of different carbon sources on callus formation, pigment accumulation, and antiviral activity in cell cultures of Euphorbia milii
Authors: Arafa Nermeen M. , Amer Ahmed M. , Girgis Nancy D. , El-Shenawy Reem , Helmy Naiera M. 
Published: August 2023

Background and aim
Humans have long been relying on plants for food, shelter, and most importantly for medicines. In vitro culture techniques, which ensure rapid, consistent, and uniform mass production, are indispensable for manufacturing important plant-derived metabolites. However, insufficient information is available regarding the tissue culture of Euphorbia milii and its important bioactive compounds. This study mainly aims to explore the impact of different carbon sources on callus formation, pigment accumulation, and antiviral activity of E. milii.

Materials and methods
Using inflorescence tissues as explants, we investigated the effects of different types and concentrations of plant growth regulators (2,4-dichlorophenoxyacetic acid [2,4-D], alone or combined with benzyl aminopurine) on callus induction frequency. Moreover, we studied the effects of different concentrations of carbon sources (glucose, fructose, and mannose) on callus growth, pigment (chlorophylls, carotenoids, and anthocyanins) accumulation, and antiviral activities.

Results and conclusion
The results indicated that 2,4-D alone (1.0 mg/l or 1.5 mg/l) induced callus formation most effectively. Furthermore, glucose was detected to be the more effective carbon source for the accumulation of chlorophylls, carotenoids, and anthocyanins compared with fructose and mannose. The highest accumulation of pigments was induced by 20 or 40 mg/l glucose supplements, with no significant difference between the effects of different concentrations. Unlike glucose, fructose or mannose did not enhance pigment accumulation; moreover, high concentrations had negative effects on pigment accumulation. Similarly, glucose was more suitable for the antiviral activity of E. milii extracts than fructose and mannose. The results will support the effective production of secondary metabolites and offer insights into the antiviral potency of E. milii.
Impact of Activity of Xanthine Oxidase on Some Biomarkers in Patients with Kidney Stones in Iraqi Patients
Authors: Rasool Ali Abdul , Ahmed Mawj Abdel Razzak 
Published: August 2023

Objective:
Kidney stones are crystalline concrete that often develops inside the kidneys. Urinary tract problems are getting worse and worse for human health. The risk of end-stage kidney failure has been associated with increase the level of a new biomarker (like xanthine oxidase) to assess severity of kidney injury.

Methods:
The eighty patients, who attended the government clinics in Yarmouk Teaching Hospital, and the forty healthy people were used as a control group. Colorimetric assays were used to assess serum xanthine oxidase (XO) and other biochemical parameters. Using an enzyme-linked immunosorbent assay was determined.

Results:
The mean serum XO activity (8.8525 IU/L) was significantly greater than the corresponding values for the controls (6.5825 IU/L). Patients with kidney stones showed abnormal activity of uric acid levels in 78.33% of cases, while XO activity showed highly sensitive (70%) and high specificity (79%). XO has been found to be an excellent biomarker for detecting damage of the kidney in people suffering from kidney stones.
Pulmonary Hypertension in a Group of Patients with Various Stages of Renal Disease
Authors: Hassan Sayf Nasseer , Al-Omary Qais Nemah Raheeem , Aldeen Ahmad Shams 
Published: August 2023

Background:
The pathogenesis of pulmonary hypertension (PHT) associated with renal failure is complex. It includes metabolic and hormonal changes, high cardiac output due to arteriovenous fistula (AVF), anemia, and other factors.

Objectives:
The objective is to identify PHT frequency and associated factors in patients on hemodialysis (HD) compared to patients, not on HD.

Methods:
A cross-sectional study was conducted at Ibn Sena teaching hospital/Mosul and included 100 diabetic males with end-stage renal disease on HD (Group 1) compared to 96 diabetic males (of similar age) with chronic kidney disease but not on HD (Group 2) to assess the pulmonary artery pressure using Doppler echocardiogram. Patients with other causes of PHT such as heart failure and chronic lung disease were excluded from the study.

Results:
42 (42%) of patients in Group 1 had PHT and 12 (12.5%) patients in Group 2. There were statistically significant differences between patients with and without PHT regarding ejection fraction (EF), but no significant differences regarding age, duration of dialysis, hemoglobin (Hb), and vascular access type in both groups.

Conclusions:
EF had a relationship with PHT, whereas the duration of dialysis, age of patients, Hb, and dialysis access type had no relationship to PHT.

Recommendations:
More studies are needed in our country regarding PHT in patients with variable stages of renal disease with larger sample sizes and different designs with the inclusion of data and parameters that were missing in our study such as duration of AVF creation.
A Pilot Study on Hypogonadism in Male Leprosy Patients in Rural Tertiary Care Hospital in Central India
Authors: Sonkusale Pratiksha Moreshwar , Kar Sumit , Deshmukh Abhay Vilas , Nandwani Subhor , Galui Sangeeta , Ambulkar Aditya 
Published: August 2023

Background:
Leprosy is a chronic granulomatous infectious disease caused by Mycobacterium leprae. Besides the skin and peripheral nerves, it also involves many internal organs. Testicular involvement is mainly seen in leprosy. Hypogonadism in males with leprosy can occur due the involvement of testis.

Aim:
The aim was to evaluate the gonadal function impairment in males with leprosy and to analyze the relation of follicle-stimulating hormone (FSH), luteinizing hormone (LH), and testosterone to the activity, duration, and disease classification in Central India.

Patients and Methods:
This was a prospective observational pilot study. We evaluated 30 patients of leprosy. They were subjected to careful history taking, dermatological and genital examination, assessment of FSH, LH, and testosterone levels, and slit skin smear for acid-fast bacilli. Diagnosis of leprosy was confirmed histopathologically. The collected data were encoded and entered electronically in a computer excel worksheet 2010 version. The statistical analysis was performed using SPSS version 17.0 for Windows. Pearson correlation coefficient was used to establish relationship between different variables. P ≤ 0.05 was considered statistically significant.

Results:
A positive correlation was found between FSH and LH hormones which was highly significant, whereas there was a negative correlation between testosterone and FSH and LH levels. There was a positive correlation between age, duration of disease, and reaction in leprosy with those of FSH and LH levels. There was a positive correlation between disease activity bacillary index (BI) and FSH, LH and a negative correlation between BI and testosterone.

Conclusion:
It is recommended that lepromatous leprosy patients should be routinely screened for hypogonadism using FSH, LH, and testosterone levels.
Pelatihan Pembuatan Nastar Jahe untuk Meningkatkan Pendapatan Keluarga pada Masa Pandemi
Authors: Asmorowati Dian Sri , Sumarti Sri Susilogati , Rahayu Endah Fitriani , Farida Noer 
Published: August 2023

Pandemi Covid-19 sangat berpengaruh pada bidang pekerjaan. Banyak orang yang tidak hanya harus Work From Home bahkan tak sedikit pula terkena PHK. Hal ini akan berpengaruh pula kondisi ekonomi masyarakat dan mempengaruhi ketahanan ekonomi keluarga. Ketahanan ekonomi merupakan kondisi terpenuhinya pangan bagi rumah tangga yang tercermin dari ketersediaan pangan yang cukup, baik jumlah, maupun mutunya, aman, merata, dan terjangkau. Keterbatasan pengetahuan mengenai pemanfaatan tanaman jahe yang ditanam dipekarangan rumah merupakan alasan utama mengapa kelompok PKK RT 8 RW 3 Desa Ngijo perlu mendapatkan pelatihan pembuatan nastar jahe, sehingga mampu mewujudkan ketahanan ekonomi keluarga. Metode pelaksanaan pengabdian ini antara lain: pelatihan untuk meningkatkan pengetahuan peserta terhadap pembuatan nastar jahe, praktik pembuatan nastar jahe, dan evaluasi kegiatan pengabdian masyarakat. Sebanyak 85% peserta mengalami peningkatan pengetahuan dan praktik pembuatan nastar jahe, sedangkan 15% peserta memiliki pengetahuan tetap. Sebanyak 80% peserta ingin melaksanakan pembuatan nastar jahe setelah diadakan pengabdian, sedangkan 20% peserta belum ingin melaksanakan pembuatan nastar jahe.
Analisis Pembelajaran Online Pada Masa Pandemi di Kelas IV Sekolah Dasar
Authors: Sutisna Atang , Komariah Kokom 
Published: August 2023

Kondisi pandemi covid-19 memaksa dunia pendidikan harus melakukan inovasi dan tetap melaksanakan proses pembelajaran, diantaranya yaitu dengan melaksanakan Pembelajaran Daring (online). Tujuan penelitian yaitu untuk menganalisis penerapan pembelajaran online di SDIT AL-Istiqomah Kuningan. Metode penelitian menggunakan kualitatif deskriptif. Teknik pengumpulan data menggunakan wawancara, dan dokumentasi. Sampel penelitian yaitu guru kelas, kepala sekolah, dan peserta didik. Hasil penelitian menunjukan bahwa implementasi pembelajaran daring di SDIT Al-Istiqomah telah sesuai dengan peraturan pemerintah bahwa kegiatan belajar mengajar dilakukan secara online menggunakan media internet yang bisa diakses di handphone, laptop dengan media komunikasi group WA. Kendala pelaksanaan pembelajaran daring diantaranya kuota internet yang terbatas, lemahnya jaringan internet, tidak semua peserta didik memiliki dan diperbolehkan menggunakan hp android. Solusi yang dilakukan adalah guru membuat video pembelajaran yang menarik, menggunakan model pembelajaran yang beragam, memberikan bahan bacaan pendamping penugasan, melakukan pembelajaran tatap maya dan membangun komunikasi baik dengan orang tua siswa.
Elaboração do Plano Individual de Transição (PIT) para jovens inclusivos do ensino médio na vida pós escola
Authors: Aguiar Aliaska Pereira , Vendruscolo Vanissia 
Published: August 2023

Para conceituar o PIT (Plano Individual de Transição) é necessário ter a empatia e a escuta projetada para a vida pós escola dos jovens inclusivos quer que seja o diagnóstico prescrito. A preparação deve estar de acordo com a abordagem pedagógica proposta pela instituição incluído um programa de práticas inclusivas. Os eixos temáticos selecionados e organizados de acordo com o projeto político pedagógico da escola e devem informaram as manifestações relacionadas ao conteúdo do Ensino Médio examinados e avaliados pela equipe gestora pedagógica e multidisciplinar com prontidão para os seguintes aspectos: funcionalidade, conteúdo e forma. O objetivo do estudo foi a elaboração de um documento modelo PIT para o conteúdo e forma dos indicadores de aprendizagem para o Ensino Médio em acordo com os eixos temáticos e as expectativas de aprendizagem, nomeadamente a sua clareza, compreensibilidade e adequação dos objetivos para o ano série. Este modelo adaptado, permitiu uma construção avaliativa eficiente que foram pontuadas em três etapas no processo (Análise; Revisão; Finalização). A elaboração integrativa faz parte de todo o processo, foi revisada e analisada para a etapa pós escola equiparado a diversidades individuais e a sensibilização para o olhar para as práticas inclusivas.
Survey Metrik Skala dan Kompleksitas Sistem Berorientasi Service
Authors: Lukmana Andy Firmansyah , Anugrah Wiratama Prayudha , Ibrahim Riswan , Ainul Yaqin Muhammad 
Published: August 2023

Survei metrik skala ini bertujuan untuk mengetahui kompleksitas dari suatu sistem berorientasi service. Sistem berorientasi service, atau dalam bahasa inggris Service Oriented Architecture (SOA), adalah gaya arsitektur sistem yang banyak digunakan oleh berbagai organisasi karena kecepatan dan kefektifan dalam proses bisnis. Namun disamping kelebihannya itu, arsitektur sistem ini memiliki kompleksitas yang berdampak pada stabilitas sistem. Resource yang didistribusikan sangat sulit untuk dikelola, dikontrol, dan mempertahankan kenaikan proporsional dengan jumlah dan keberagaman sistem, komponen, dan platform. Dan saat ini tidak banyak metrik skala dapat digunakan untuk mengukur kompleksitas tersebut. Oleh karena itu, tujuan dari tulisan ini adalah untuk mengulas metrik skala dalam mengukur kompleksitas sistem berorientasi service, yang kemudian dilakukan uji hipotesa dan analisis untuk menunjukkan jika resource terdistribusikan dengan imbang pada sistem
REVIEW ON - FOLK LITERATURE TO REDEVELOP VOCATIONAL EDUCATION THROUGH SKILL DEVELOPMENT IN INDIA
Authors: Gajjar Dharti 
Published: August 2023

The word, ‘folk’ has wide range of understanding and connotations-ranging from ‘natural’ to traditional’ to ‘rural’ and in some cases ‘from the heart’ in India. Very ancients of this land, India, were past masters of all art forms that are folk. Folk literature also called folklore or oral tradition is that the lore (traditional knowledge and beliefs) of cultures having no written communication. In the new National Education Policy-2020 several important guidelines to preserve the tradition of multilingualism and folk wisdom have been given. Its background is based on folk Literature. In the context of globalisation, and changes to work patterns it is failing to redevelop vocational education resources to industries.
The paper starts with folk literature and India’s Vocational Education and training which is essential mechanism of any strategy to improve farm and nonfarm productivity that improves rural incomes. Skill is the bridge between job and workforce. The discussion will go on to use of materials from folk literature for purposes of instruction at various levels of education is rather minimal included vocational education emerging with National Education Policy-2020. Finally, an attempt to make use of folk literature as a powerful educational tool to redevelop vocational education through skill development in India as it could be to increase inclusivity, innovation and prosperity. Efforts have to be made to sensitize our young learners towards the rich folk heritage of India and give it the prestigious position that it deserves in our life.
The process of handcuffing persons
Authors: Dalcaran Cristina-Andreea 
Published: August 2023

In Romania, the police are among the institutions whose aim is to defend civil rights and liberties, as well as train citizens to comply with the laws or punish those who deviate from the rules and principles of a modern and fair society.
The police generally perform work in the field, having direct contact with citizens, to ensure public order and peace, tracking and enforcement of the law.
The policeman is obliged to intervene on any person, regardless of the position that person holds in society, gender or race, when he endangers the security of the state, the rights and freedoms of other people.
In some situations, the warning given by the police to a person is enough for that person to stop committing illegal acts, but there are also situations in which it is necessary to use the means of immobilization, force or even the weapons provided. These situations endanger the physical integrity of the policeman or even his life, because of violent people. The utility of the existence of theories and practices of police intervention is caused by the fact that there are no complete articles in the law regarding the rights and freedoms of police officers on duty, for solving all cases. Compliance with these theoretical and practical rules protects police officers from abuses and deviations in interventions.
Missions will be solved successfully and carried out, only if the most effective procedures and methods are respected, which is exactly why the policeman is obliged to respect these rules.
The Coastal Surveillance Through Observation of Ocean Color (COASTℓOOC) dataset
Authors: Massicotte Philippe , Babin Marcel , Fell Frank , Fournier-Sicre Vincent , Doxaran David 
Published: August 2023

Abstract. Coastal Surveillance Through Observation of Ocean Color (COASTℓOOC) oceanographic expeditions were conducted in 1997 and 1998 to
examine the relationship between the optical properties of seawater and related biological and chemical properties across the coastal to open-ocean
gradient in various European seas. A total of 379 stations were visited along the coasts of the Gulf of Lion in the Mediterranean Sea (n=61),
the Adriatic Sea (n=39), the Baltic Sea (n=57), the North Sea (n=99), the English Channel (n=85), and the Atlantic Ocean (n=38). Particular emphasis
was placed on the collection of a comprehensive set of apparent and inherent optical properties (AOPs and IOPs) to support the development of ocean
color remote-sensing algorithms. The data were collected in situ using traditional ship-based sampling but also from a helicopter, which is a very
efficient means for that type of coastal sampling. The dataset collected during the COASTℓOOC campaigns is unique in that it is
fully consistent in terms of operators, protocols, and instrumentation. This rich and historical dataset is still today frequently requested and
used by other researchers. Therefore, we present the result of an effort to compile and standardize a dataset which will facilitate its reuse in
future development and evaluation of new bio-optical models adapted for optically complex waters. The dataset is available at https://doi.org/10.17882/93570 (Massicotte et al., 2023).
Aplikasi Pelayanan Administrasi Desa Sidangoli Dehe Berbasis Web Mobile
Authors: Senen Diana , Hamid Mustamin , Sudin Sakina 
Published: August 2023

Penelitian ini menggunakan metode web mobile untuk membuat Aplikasi Pelayanan Administrasi Desa Sidangoli Dehe dengan tujuan untuk mempermudah Pelayanan dan kepada Masyarakat di Desa Sidangoli Dehe. Permasalahan yang ada pada Pemerintah Desa Sidangoli Dehe Kabupaten Halmahera Barat, yaitu perlu diperhatikan dalam pelayanan Administrasi terhadap Masyarakat masih menggunakan sistem konvesional, yang pelayanannya mewajibkan masyarakat harus datang ke Kantor Desa dan harus langsung bertatap muka dengan Kepala Desa atau Sekertaris Desa untuk proses validasi pengesahan pengurusan surat-surat data kependudukan. Hal terebut dinilai kurang efektif, apabila Pejabat Desa saat tidak berada di Kantor Desa karena ada kepentingan atau tuntutan dari dinas. Akibatnya pelayanan tersebut terhambat membutuhkan validasi dari Kepala Desa atau Sekertaris Desa. Solusi yang peneliti usulkan adalah sebuah sistem aplikasi pelayanan administrasi desa sidangoli dehe berbasis web mobile. Aplikasi berbasis web mobile menggunakan bahasa pemrograman php dan mysql.

Kata kunci : Aplikasi, Pelayanan , Administrasi, Desa, Sidangoli Dehe
Monstrous Disembodiment and Ontological Uncertainty in Charybdis
Authors: Denson Ryan 
Published: August 2023

ABSTRACT
Charybdis is a well-known sea monster in both the ancient and modern imaginations resulting from her prominent appearance in the Odyssey. Yet, in contrast to her counterpart across the strait, Scylla, she has been overlooked by modern scholars, and few have examined what makes her monstrous in the first place. This article will argue that Charybdis should be understood as monstrous as a result of her lack of corporeality, which, in turn, also results in an ontological uncertainty about whether or not she is even a natural phenomenon or, rather, a supernatural monster. The type of fear and unease that Charybdis’s unique form of monstrosity exerts on humans can, then, be best described with reference to Mark Fisher’s concept of “the eerie” as a failure of presence where we expect it to be.
The “Western” Folk Healer as a Symbolic Healer: A Case Study from a Magic Ritual in Northern Greece
Authors: Barmpalexis Athanasios 
Published: August 2023

ABSTRACT
The article, based on the author’s doctoral research on the life and work of contemporary folk healers with shamanistic knowledge in North East Scotland, explores one key issue when it comes to healing traditions: What kind of healing do these individuals offer? In 1986, anthropologist James Dow, expanding on Daniel Moerman’s idea that all spiritual healers are in fact symbolic healers, suggested that these folk specialists use human communication, ritual, and culture-specific symbols as tools to heal others. Drawing from the author’s ethnographic fieldwork alongside one such spiritual healer, the article examines the healer’s symbolic healing approaches through the example of a spontaneous magic ritual he conducted in autumn 2015 in Greece. The article’s goal is to ethnographically demonstrate how the healer’s practices fit into Dow’s “symbolic healing” scheme as an integral component for the efficiency of his healing practices.
Pengajaran Bahasa Inggris untuk anak-anak Jalanan Save Street Child Palopo
Authors: Hermini  , Reski Pilu  
Published: August 2023

Pengabdian Pengajaran Bahasa Inggris untuk anak-anak jaIanan Save Street Child PaIopo bertujuan untuk memperkenalkan Bahasa Inggris kepada anak-anak Jalanan pada komunitas Save Street Child PaIopo. Target dari kegiatan ini adalah siswa anak-anak jalanan Save Street Child Palopo yang berjumlah 20 orang dengan rentang usia 7 (tujuh)- 13 (tiga belas) tahun yang dibagi menjadi 2 (dua) kelompok. Pengabdian ini dilaksanakan dalam tiga tahap yaitu: (1) tahap perencanaan, (2) tahap pelaksanaan dan (3) tahap evaluasi. Hasil dari kegiatan ini menunjukkan seluruh peserta merasa sangat senang dan antusias. Ini terlihat dari sikap dan semangat mereka yang nampak mulai dari awal hingga akhir kegiatan. Dan hasil akhirnya adalah, mereka dapat mengetahui dan menggunakan kosa kata daIam Bahasa Inggris baik keIompok 1 dan keIompok 2. Dengan kegiatan pengabdian masyarakat ini anak-anak jalanan dapat mengenaI kosa kata daIam Bahasa Inggris, meIafaIkan, dan mengetahui makna kosa kata daam Bahasa Inggris