bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of prognostic indicator based on NAD+ metabolism related genes in glioma
Authors: Chen Xiao , Wu Wei , Wang Yichang , Zhang Beichen , Zhou Haoyu , Xiang Jianyang , Li Xiaodong , Yu Hai , Bai Xiaobin , Xie Wanfu , Lian Minxue , Wang Maode , Wang Jia 
Published: January 2023

BackgroundStudies have shown that Nicotinamide adenine dinucleotide (NAD+) metabolism can promote the occurrence and development of glioma. However, the specific effects and mechanisms of NAD+ metabolism in glioma are unclear and there were no systematic researches about NAD+ metabolism related genes to predict the survival of patients with glioma.MethodsThe research was performed based on expression data of glioma cases in the Cancer Genome Atlas (TCGA) and Chinese Glioma Genome Atlas (CGGA) databases. Firstly, TCGA-glioma cases were classified into different subtypes based on 49 NAD+ metabolism-related genes (NMRGs) by consensus clustering. NAD+ metabolism-related differentially expressed genes (NMR-DEGs) were gotten by intersecting the 49 NMRGs and differentially expressed genes (DEGs) between normal and glioma samples. Then a risk model was built by Cox analysis and the least shrinkage and selection operator (LASSO) regression analysis. The validity of the model was verified by survival curves and receiver operating characteristic (ROC) curves. In addition, independent prognostic analysis of the risk model was performed by Cox analysis. Then, we also identified different immune cells, HLA family genes and immune checkpoints between high and low risk groups. Finally, the functions of model genes at single-cell level were also explored.ResultsConsensus clustering classified glioma patients into two subtypes, and the overall survival (OS) of the two subtypes differed. A total of 11 NAD+ metabolism-related differentially expressed genes (NMR-DEGs) were screened by overlapping 5,995 differentially expressed genes (DEGs) and 49 NAD+ metabolism-related genes (NMRGs). Next, four model genes, PARP9, BST1, NMNAT2, and CD38, were obtained by Cox regression and least absolute shrinkage and selection operator (Lasso) regression analyses and to construct a risk model. The OS of high-risk group was lower. And the area under curves (AUCs) of Receiver operating characteristic (ROC) curves were &gt;0.7 at 1, 3, and 5 years. Cox analysis showed that age, grade G3, grade G4, IDH status, ATRX status, BCR status, and risk Scores were reliable independent prognostic factors. In addition, three different immune cells, Mast cells activated, NK cells activated and B cells naive, 24 different HLA family genes, such as HLA-DPA1 and HLA-H, and 8 different immune checkpoints, such as ICOS, LAG3, and CD274, were found between the high and low risk groups. The model genes were significantly relevant with proliferation, cell differentiation, and apoptosis.ConclusionThe four genes, PARP9, BST1, NMNAT2, and CD38, might be important molecular biomarkers and therapeutic targets for glioma patients.
An Exploration of Sedentary Behavior, Physical Activity, and Quality of Life During the COVID-19 Outbreak
Authors: Huang Cheng-Yen , Huang Wen-Hsin , Yen Hsin-Yen 
Published: January 2023

Objectives: Staying physically active is a cost-efficient strategy for disease prevention during a pandemic. The purposes of this study were to explore precautionary behaviors, psychological factors associated with physical activity and sedentary behavior, and impacts of active and sedentary lifestyles on the quality of life in the early stage of the coronavirus disease 2019 (COVID-19) outbreak.Methods: Participants were community-dwelling adults aged over 20 years who had not been infected with COVID-19 and who lived in the United States. A study with a cross-sectional design was conducted between July and October 2020. Quantitative data were collected by a self-reported questionnaire.Results: In total, 467 valid responses were obtained. Participants who engaged in an active lifestyle had significantly higher scores on all domains of quality of life compared to those who engaged in an inactive lifestyle. Participants with a non-sedentary lifestyle had significantly higher scores of psychological and social domains of quality of life than those with a sedentary lifestyle.Conclusion: Engaging in an active lifestyle and avoiding a sedentary lifestyle are recommended when facing future, unpredictable pandemics similar to COVID-19.
Evaluation of Ecosystem Services Radiation Assessment of the National Ecological Sheltering Zone in China
Authors: Su Kai , Jiang Xuebing 
Published: January 2023

Ecosystem services (ES) have been shrinking due to unreasonable development and utilization for a long time. There are many studies on ES, but the ecological information for policymakers is still complex and obscure. To address this critical omission, based on remote sensing data, combined with meteorological data, land use data, and administrative division data, using GIS spatial analysis technology and some ecological process models, we develop an ecosystem services radiation assessment framework (ESRAF) that can provide policymakers with concise and reliable ecological information. We illustrate the measurement of ESRAF through an application to specific regions of China’s national ecological sheltering zone (NESZ), showing that the approach can effectively identify the beneficiary areas (SBA) for sand-stabilization service, soil conservation service, and water conservation service, and the degree of sharing of ES of SBA. ES produced by ecosystems in a specific region not only generates huge benefits locally but also a large number of ES benefit surrounding regions through cross-regional transmission. Specifically, in 2015, the area benefiting from sand-stabilization service provided by the Ordos’s ecosystem is about 1.66×106 km2, the amount of dust reduction in SBA would reduce by 28,738.67×104 tons. The Loess Plateau Ecological Screen (LPES) provides critical soil conservation service, the SBA of LPES includes two parts: LPES and the Yellow River. The Northeast Forest Belt (NFB) provides vital water conservation services. The water conservation service beneficiary area is mainly located near the NFB, with 266 hydrological response units, covering an area of 8.982×104 km2. This study also showed that the transmission distance is inversely proportional to the radiation effect, that is, the benefit level decreases with the distance from SPA. According to the degree of sharing of ES of SBA, the proposed cross-regional differentiated ecological compensation scheme is helpful to promote regional sustainable development. At the same time, this study also shows that NESZ is of great significance for ensuring China’s ecological security.
Application of EMS system for continuous measurement of rheology in reaction chamber
Authors: Hosoda M. , Yamakawa Y. , Sakai K. 
Published: January 2023

Abstract
The electromagnetically spinning method for viscosity measurement was enhanced for applications in a confined reaction chamber. In the reaction chamber, the immersion of the rotor into the sample might trigger the precipitation and aggregation of ingredients to the pivot of the probe rotor, which leads to harmful frictional torque of the rotation. To address this problem, an upper-point-type auto-standing probe rotor was developed and applied for the long-term measurement of the solution process of rock sugar in water. In addition, we propose the adoption of a punched board, instead of a solid board, as the lower substrate of the plate-plate-type rotational viscometer, which allows rapid exchange of the sample fluid between the interior and exterior of the narrow measurement area through molecular diffusion. We investigated the effect of punches from the perspective of the diffusion process of momentum and determined the geometrical conditions.
How to fix an ultrasonic variable-focus liquid crystal lens for substrate-mountable applications
Authors: Kuroda Yuma , Harada Yuki , Onaka Jessica , Emoto Akira , Matsukawa Mami , Koyama Daisuke 
Published: January 2023

Abstract
This paper proposed a board-mounted ultrasonic variable-focus liquid crystal (LC) lens. The lens controls the focus using the acoustic radiation force generated by the resonant flexural vibration mode. The LC lens was fixed to an aluminum substrate with a hole whose aperture corresponded to the inner diameter of the transducer. The part of the LC lens attached to the substrates functioned as a fixed condition, and the flexural vibration mode was successfully generated. The fixed lens exhibited a gradual focal change with current, confirming that fixing the condition affected the rate of focal change.
10 kW peak power, single-frequency 1553 nm nanosecond pulsed fiber laser for time-of-flight LIDAR
Authors: Zhang Zhitao , Li Zheng , Yu Hanghang , Xuan Hongwen 
Published: January 2023

Abstract
A 10 kW peak power, 10 ns duration and 6 kHz repetition rate fiber laser system at 1553 nm based on an Er/Yb co-doped large-mode-area fiber, is demonstrated experimentally. The seed laser is provided by a DFB laser switched with a semiconductor optical amplifier. Its optical spectrum, linewidth, and beam quality are measured and discussed. This pulsed laser with short pulse duration and high peak power could be a candidate for the laser source of time-of-flight light detection and ranging (LIDAR).
دراسات "جندرية "( النوع الاجتماعي) في فقه المرأة
Authors: الحسون بتول 
Published: January 2023

إن موقف الإسلام من المرأة واضح في الآيات القرآنية إذ أشار الإسلام إلى المساواة بين الذكر والأنثى ، لكن النظرة الجنسانية التقليدية التي سادت على المرأة بأنها عاطفية وأنها مناسبة فقط للإنجاب ، هو مايدفع الى إيجاد تحيز جنسي لصالح الذكور في حقوق الإنسان والمعرفة الدينية ، لذا فإن هذا البحث سيتطرق إلى بعض هذه المواقف ، وبعض التناقضات بين الجنسين ، والتحيزات ضد المرأة ، مما جعل العرب وغيرهم من الذين دخلوا الإسلام يفسرون الدين أولاً على نحو يسيء إلى الإسلام ، وتوصي الدراسة بإعادة قراءة الفقه والنصوص التشريعية في ضوء مفاهيم حقوق الإنسان الحديثة ، لأن الدين الإسلامي هو الدين الأخير ويفترض أن يقدم رؤية حديثة تناسب كل عصر. كما أن البحث يوصي بضرورة قراءة تشريعات المرأة والمساهمة في نضج واقع اجتهاد واعي للاختلافات بين الجنسين تجاه الدين
الثنائيات الضدية في أشعار ابن فركون الاندلسي
Authors: یوسفي حسین , الخضري أحمد 
Published: January 2023

ثنائيات الضدية هو ان يؤتى بمعنيين او اكثر وبعدها تذكر أضدادهما، على ان يكون التقابل بالترتيب. وتعتبر الثنائيات الضدية او التقابل البلاغي احد ابرز أساليب نظم المعاني كما انه احد سبل البيان التي تجد فيها المعاني معرضا للدقة والجمال، والتي تعطي للنص لذة ومتعة، فهو أسلوب بلاغي بديعي يكثر حضوره في الشعر، ويستخدم كأداة فنية لبيان المعاني الحقيقة والاغراض البلاغية. ونظرا لبلاغة هذا الفن فقد استخدمه الشعراء ومن ضمنهم ابن فركون الاندلسي حتى صبغ اغلب شعره.
تعددت مظاهر الثنائيات الضدّية في شعر ابن فركون الاندلسي وذلك لعدة اسباب ابرزها ان الشاعر كان ينطلق من بيئة أدبية اندلسية اشتهرت بحبها للزخرفة البديعية وقد تأثر الشاعر في ذلك من الجو الأدبي والذوق العام، كما ان تقلب الواقع الاندلسي بين الحروب والسلام والصراع والصلح والنعيم والبؤس والاستقرار والاضطراب كل ذلك قد ترك اثره في شعره فضلا عن ذلك فقد استعان الشاعر بهذا الفن للتعبير عن الكثير من افكاره وعواطفه ورؤاه من خلال الثنائيات الضدية والتقابل البلاغي. وقد استخدم الشاعر كل انواع الثنائيات الضدية سواء الطباق والمقابلة بمختف انواعها الإيجابية والسلبية الا اننا هنا نقتصر بحثنا علي التقابل نظرا لما تمتاز به من دور فنّي بديع. ويجدر التنويه الي ان هناك ضربان من المقابلة فمنها ما هو لفظي واضح ومنها ما هو معنوي يستنبط يفهم من سياق الكلام وهذا ما نتناوله ضمن التحليل.
Predictores sociodemográficos de la satisfacción con la vida en escolares de instituciones educativas públicas de la ciudad de Arequipa
Authors: Arias Gallegos Walter Lizandro , Huamani Cahua Julio Cesar 
Published: January 2023

This study analyzes some sociodemographic factors, which could predict the satisfaction with life in a sample of high school students from Arequipa, following the theoretical frame of the Positive Psychology. We tested a sample of 872 students of 4th and 5th grade, from five public local high schools, who were 46.9 % males and 53.1 % females. A sociodemographic chart and the Satisfaction with Life Scale were applied, in the version validated to Arequipa City (Arias, Huamani, & Caycho-Rodríguez, 2018). The data was processed by structural equations modeling. The results indicate that sex and school have some predictive power over life satisfaction.
Pemberian Gonad Deadema Setosum terhadap Berat Badan dan Panjang Badan Tikus Jantan Wistar (Rattus Norwegiccus) Kurang Gizi Kronik
Authors: Fathurrahman Teguh , Wiralis W , Zakaria Z , Hariani H 
Published: January 2023

Pendahuluan
Gizi kurang kronis dapat mengakibatkan stunting. Penambahan gonad Deadema setosum pada pembuatan produk makanan tambahan sebagai alternatif PMT berbasis bahan pangan lokal. Gonad Bulu babi mengandung asam amino esensial, asam lemak esensial, mineral dan vitamin yang dibutuhkan untuk pemeliharaan jaringan pada masa pertumbuhan. Penelitian ini bertujuan untuk menganalisis perbedaan panjang badan dan berat badan setelah pemberian gonad Deadema setosum pada model eksperimen.
Metode
Penelitian merupakan eksperimen laboratorium menggunakan model tikus jantan wistar (Ratus norwegiccus) kurang gizi kronik. Tikus usia 5 minggu, rancangan penelitian pre-post test with group control. Penelitian dilakukan selama 6 bulan (juli sampai desember 2020). Model eksperimen diinduksi dengan asupan rendah energi selama 24 hari pada 75 ekor sampel tikus untuk menghasilkan sampel tikus wasting. Tikus wasting sebanyak 15 ekor tikus yang dipilih secara random, diberi perlakuan :K+ (pakan standar+injeksi hormon pertumbuhan 1 ml), K- (pakan standar), F1 (pakan standar + tepung gonad 1 gram/hari), F2 (pakan standar + tepung gonad 2 gram/hari) dan F3 (pakan standar + tepung gonad 3 gram/hari) selama 12 hari. Data dianalisis secara deskriptif dan analitik.
Hasil
pemberian tepung gonad Bulu babi Deadema setosum 3 gram per hari (F3) dapat menambah panjang badan (0,15 cm) lebih cepat dibandingkan F2 : pemberian tepung gonad 2 gram/hari (0,13 cm), 1 gram/hari (0,06 cm) dan kelompok kontrol negatif (0,04 cm). Pemberian tepung gonad 3 gram/hari dapat menambah berat badan sampel sama dengan kontrol positif (0,4 gram) tinggi dibandingkan F2 (0,3 gram) dan F1 sama dengan kontrol negatif (0,1 grm) pada model eksperimen Rattus norwegicus . Hasil analisis statistik menunjukkan tidak ada perbedaan panjang badan (p= 0,903) dan berat badan (p=0,928) setelah pemberian tepung gonad.
Kesimpulan dan Saran
Pemberian tepung gonadTidak ada perbedaan panjang badan dan berat badan pada tikus setelah pemberian tepung gonad 1,2 dan 3 gram dengan kelompok yang mendapatkan injeksi hormone dan yang yang tidak mendapatkan suplemen selama 12 hari. Pemberian tepung gonad Bulu babi Deadema setosum diberikan > 3 gram/hari waktu yang lebih lama untuk melihat perubahan berat badan dan panjang badan.
Hubungan Pendidikan Ibu dengan Kejadian Kekurangan Energi Kronik pada Ibu Hamil pada Masa Pandemik COVID-19 di Wilayah Kerja Puskesmas Kabupaten Konawe
Authors: Kartini Kartini , H Mukaddas 
Published: January 2023

Pendahuluan
Kekurangan energi kronik merupakan suatu keadaan yang disebabkan ketidakseimbangan antara asupan gizi antara energi dan protein, sehingga zat gizi tubuh tidak tercukupi. Penelitian ini bertujuan untuk mengetahui hubungan Pendidikan ibu dengan kekurangan energi kronik (KEK) ibu hamil pada masa pandemik covid 19 di Wilayah Kerja Puskesmas Kabupaten Konawe.
Metode
Penelitian ini menggunakan metode observasional dengan rancangan penelitian cross sectional.Instrumen penelitian mengunakan kuesioner dan melakukan observasional pada sejumlah responden. Analisis data menggunakan uji Chi Square pada derajat kepercayaan (CI) 95 % dengan nilai kemaknaan (p<0.05).
Hasil
Hasil penelitian menunjukan bahwa jumlah ibu hamil kek sebanyak 42 orang (36,5%), pendidikan terbanyak ibu adalah rendah (SD dan SMP) dan menengah (SMA/Sederajat) masing-masing sebanyak 39 orang (33,9%). Ibu yang berpendidikan rendah yang mengalami kek sebanyak 24 orang (20,9%), menengah sebanyak 14 orang (12,2%), tinggi sebanyak 4 orang (3,5%). Ibu yang berpendidikan rendah yang tidak mengalami kek sebanyak 15 orang (13,0%), menengah sebanyak 25 orang (21,7%), tinggi sebanyak 3 orang (28,7%).
Kesimpulan dan Saran
Hasil analisis data menunjukkan nilai p value = 0,000. Dapat disimpulkan bahwa ada hubungan pendidikan dengan kejadian kekurangan energi kronik (KEK) ibu hamil pada masa pandemik covid 19 di Wilayah Kerja Puskesmas Kabupaten Konawe (p<0.05).
IDENTIFYING NEWLY DIAGNOSED DIABETES MELLITUS RISK FACTORS USING GRAPHICAL NETWORKS WITH EXPERT KNOWLEDGE
Authors: Lim Ooi Wei , Dass Sarat C 
Published: January 2023

An increasing trend of newly diagnosed diabetes mellitus (DM) among adolescents is occurring worldwide, including Malaysia. This study aims to determine the overall relationships between risk factors on the prevalence of newly diagnosed diabetes mellitus among Malaysian adolescents. Current study uses a cross-sectional study, data from the Fifth National Health and Morbidity Survey 2015 which consists of individuals who ages 18 and above, extraction of 18 and 19 years old from the data set was done.. Bayesian networks modelling was performed by using graphical networks with expert knowledge to identify the risk factors of newly diagnosed diabetes mellitus among adolescents in Malaysia. Education levels, Body Mass Index (BMI), and physical inactivity were identified as the significant predictors of newly diagnosed DM. The highest conditional probability of developing newly diagnosed DM belongs to both obese and underweight respondents given they have no formal education (probability, pr = 0.5000), followed by obese respondents who had unclassified level of education (pr = 0.4709), and obese respondents with primary level of education (pr = 0.4692). The findings of current study provide insights and allows policymakers to plan for future interventions in order to monitor and reduce the high prevalence of newly diagnosed diabetes mellitus among adolescents in Malaysia.
THE INFLUENCE OF THE MOTIVE FOR THE USE OF AUDIO-VISUAL DA'WAH MEDIA ON INCREASING THE SATISFACTION OF DA'WAH MESSAGES IN SURABAYA ISLAMIC STUDENTS
Authors: Nanik Mujiati  
Published: January 2023

The studies background of audio-visual media use as the da’wah media often accessed by Surabaya Islamic students. The study aims to see how the motive of the use of audio-visual da’wah media on the increasing satisfaction of the da’wah message on Surabaya Islamic students has been. Research answer the problems, 1) what was the motive behind the use of audio-visual da’wah media toward the increasing satisfaction of the da’wah message on Surabaya Islamic students? 2) what percentage of the motive behind the use of audio-visual da’wah media on the increasing satisfaction of the da’wah message on Surabaya Islamic students?. Data collection techniques this research through questionnaires, observation, interviews, and documentation. The technical data analysis is done in statistical quantitative. Based on research, it is known that there has been a significant influence on the use of audio-visual da’wah media toward the increased satisfaction of the da’wah message on Surabaya Islamic students. The motive for the use of audio-visual da’wah media on raising the satisfaction of the da’wah message on Surabaya Islamic students is 10,8 %.
Keywords: Da’wah, Audio-visual Media, Da’wah Message.
SEMIOTICS ANALYSIS OF THE INDONESIAN HALAL LOGO (STUDY OF ROLAND BARTHES ANALYSIS OF SEMIOTICS)
Authors: Yunita Indinabila  
Published: January 2023

The Presence of Law no. 33 of 2014 concerning Halal Product Assurance mandated by Badan Penyelenggara Jaminan Produk Halal (BPJPH) has an impact on changing the halal logo in Indonesia. Now the Indonesian halal logo consists of a logogram and logotype. Using semiotic analysis from Roland Barthes, researchers try to examine the signs, connotations, and myths on the Indonesian halal logo.
The use of kufi calligraphy in logotypes is inseparable from its history, that kufi khat has been used since the time of Rasulullah SAW. Furthermore, in its application, logogram and logotype cannot be separated.
The researcher analyzed the use of white as the background in the logo, representing that BPJPH wants to show a new beginning based on the values of purity, sincerity, simplicity, and independence. The purple color in the logogram and logotype is believed to represent faith, piety, and high imagination. Historically, purple has represented courage. Apart from purple, this logo also has turquoise as its secondary color. Toska is considered to represent wisdom, calm, and stability.
Temporal Behaviors of Magnetic Helicity Injections by Self and Mutual Sunspot Rotations
Authors: Hasegawa Takahiro , Shimizu Toshifumi 
Published: January 2023

Abstract
Magnetic helicity is a physical parameter used to quantify the complexity of magnetic fields, providing an indication of the energy state in the coronal magnetic structure. We investigate the temporal evolution of magnetic helicity and its relationship to the occurrence of a variety of flares in the solar active region NOAA 12297, which was well observed using the Solar Dynamics Observatory/Helioseismic and Magnetic Imager in 2015 March. The active region produced many M-class flares and an X-class flare in two distinctive areas, both of which had a similar magnetic evolution, i.e., the opposite polarity of an emerging flux developed beside a preexisting sunspot, but exhibited flares with different magnitudes and frequencies. We derived the spatiotemporal evolution of the magnetic helicity injections and evaluated how spinning and braiding helicity injections evolved with time in the two areas. In one area, we observed a remarkable evolution, in which a negative spinning helicity injection in the preexisting sunspot increased in a positive helicity system, followed by the occurrence of the X-class flare. The negative helicity injection was clearly caused by the flux emergence that developed along the outer edge of the preexisting sunspot. The other area showed positive braiding helicity injections, with spinning helicity injections fluctuating concurrently with flux emergence, changing their signs several times, i.e., variable energy, and helicity input. The observed temporal behaviors of the helicity injections may explain different types of flare occurrences in the regions.