bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between immune checkpoint inhibitors and myocardial infarction in Asians: A population‐based self‐controlled case series
Authors: Chan Jeffrey Shi Kai , Tang Pias , Lee Teddy Tai Loy , Chou Oscar Hou In , Lee Yan Hiu Athena , Li Guoliang , Leung Fung Ping , Wong Wing Tak , Liu Tong , Tse Gary 
Published: February 2023

AbstractBackgroundWhile immune checkpoint inhibitors (ICIs) are associated with elevated cardiovascular risks, evidence of any association between ICIs and myocardial infarction (MI) was scarce, especially in Asians.MethodsUsing prospectively collected population‐based data, this self‐controlled case series included patients prescribed an ICI between 1/1/2014 and 31/12/2020 in Hong Kong who had MI within January 1, 2013 to December 31, 2021. Incidence rate ratios (IRRs) for MI during and after ICI exposure were estimated, compared to the year before ICI initiation.ResultsOf 3684 identified ICI users, 24 had MI during the study period. MI incidence increased significantly in the first 90 days of exposure (IRR 3.59 [95% confidence interval: 1.31–9.83], p = 0.013), but not days 91–180 (p = 0.148) or ≥181 (p = 0.591) of exposure, nor postexposure (p = 0.923). Sensitivity analyses excluding patients with MI‐related death and incorporating extended exposure periods produced consistent results separately.ConclusionsICIs were associated with increased MI incidence in Asian Chinese patients during the first 90 days of use, but not later.
Value co‐creation and customer retention in services: Identifying a relevant moderator and mediator
Authors: Banik Shanta , Rabbanee Fazlul K. 
Published: February 2023

AbstractThis research explores the effects of the DART model of value co‐creation on customer retention. To do so, the current research examines the moderating role of types of customer (i.e., corporate vs. retail) and the mediating effect of customer engagement. Two studies were conducted through structured surveys among 362 bank customers (Study 1) and 316 hotel customers (Study 2). Partial least‐squares‐based structural equation modeling (PLS‐SEM) was employed to analyze the data. The results of Study 1 show that each element of the DART model significantly influences customer retention. The effects of dialog, risk assessment, and transparency on customer retention are found to be higher (lower) for corporate (retail) customers, while the effect of access on customer retention is higher (lower) for retail (corporate) customers. Study 2 further identified customer engagement as a mediator explaining the underlying mechanism in the links between each element of the DART model and customer retention. Theoretical contributions and managerial implications of the findings are discussed.
Controlling Activity of Heterogeneous Cu Single‐Atom Catalysts by Fine‐Tuning the Redox Properties of CeO2‐TiO2 Supports
Authors: Abdel‐Mageed Ali M. , Cisneros Sebastian , Mosrati Jawaher , Atia Hanan , Vuong Thanh Huyen , Rockstroh Nils , Wohlrab Sebastian , Brückner Angelika , Rabeah Jabor 
Published: February 2023

AbstractUnderstanding and enhancing the activity of heterogeneous single‐atom catalysts (SACs) are indispensable aspects to use them in industrial applications. Among these, low‐temperature CO oxidation is considered as a model reaction for testing a wide‐range of oxidation catalysts, and as an essential process for the exhaust aftertreatment in modern combustion engines. This study demonstrates that the activity of heterogeneous Cu/CeO2−TiO2 SAC catalysts can be fine‐tuned by controlling the Ce/Ti ratio in CeO2−TiO2 supports, with the highest catalytic activity achieved for a Ce/Ti molar ratio of 0.18. Based on DRIFT, EEL, and EPR spectroscopies, together with high‐resolution electron microscopy and H2‐TPR measurements, it is inferred that the optimized Ce/Ti ratio correlates with i) highest dispersion of separate CeO2 particles on TiO2 surface, ii) more facile reduction of Ce4+ to Ce3+, and iii) enhanced formation of −Cu2+−O−Ce4+−⇆−Cu+−□−Ce3+− redox shuttles, which play a dual role for CO adsorption and O2‐activation. These results extend the understanding of heterogeneous metal single‐atom catalysts and constitute a robust approach for the rational control of their catalytic performance in technically relevant applications.
Associations between diagnosis with stroke, comorbidities, and activity of daily living among older adults in the United States
Authors: Ruksakulpiwat Suebsarn , Zhou Wendie , Phianhasin Lalipat , Benjasirisan Chitchanok , Salehizadeh Saeideh , Wang Limin , Voss Joachim G. 
Published: February 2023

AbstractBackgroundStroke is the leading cause of mortality. This study aimed to investigate the association between stroke, comorbidities, and activity of daily living (ADL) among older adults in the United States.MethodsParticipants were 1165 older adults aged 60 and older from two waves (2016 and 2018) of the Health and Retirement Study who had a stroke. Descriptive statistics were used to describe demographic information and comorbidities. Logistic regressions and multiple regression analyses were used to determine associations between stroke, comorbidities, and ADL.ResultsThe mean age was 75.32 ± 9.5 years, and 55.6% were female. An adjusted analysis shows that older stroke adults living with diabetes as comorbidity are significantly associated with difficulty in dressing, walking, bedding, and toileting. Moreover, depression was significantly associated with difficulty in dressing, walking, bathing, eating, and bedding. At the same time, heart conditions and hypertension as comorbidity were rarely associated with difficulty in ADL. After adjusting for age and sex, heart condition and depression are significantly associated with seeing a doctor for stroke (odds ratio [OR]: 0.66; 95% confidence interval [CI]: 0.49–0.91; p = 0.01) and stroke therapy (OR: 0.46; 95% CI: 0.25–0.84; p = 0.01). Finally, stroke problem (unstandardized β [B] = 0.58, p = 0.017) and stroke therapy (B = 1.42, p < 0.001) significantly predict a lower level of independence.ConclusionThis study could benefit healthcare professionals in developing further interventions to improve older stroke adults' lives, especially those with a high level of dependence.
Single‐Site Molecular Ruthenium(II) Water‐Oxidation Catalysts Grafted into a Polymer‐Modified Surface for Improved Stability and Efficiency
Authors: Badiei Yosra M. , Annon Oshane , Maldonado Christina , Delgado Emily , Nguyen Caroline , Rivera Christina , Li Clive , Ortega Abril Flores 
Published: February 2023

AbstractWater‐oxidation is a mechanistic bottleneck in artificial photosynthesis that is critical for achieving sustainable energy‐to‐fuel conversion. Grafting molecular water‐oxidation catalyst assemblies on the surface of a polymer can engender better stability and higher efficiency. Herein, we present a hybrid construct which consists of a molecular single‐site RuCat1 encapsulated into a UV cross‐linked polymer assembly on an F‐doped tin oxide (FTO). Incorporation of high‐density surface‐binding sites (COO− groups) resulted in a high surface loading of the RuCat1 and surface stability as shown from ATR‐FTIR, UV‐vis and cyclic voltammetry data. Furthermore, we found that the grafted RuCat1 into the polymer brush layers promotes pH‐dependent electrocatalytic water‐oxidation with a turnover frequency of 0.45 s−1 and an estimated 88 % faradaic efficiency during control potential electrolysis at pH 8.5. The general applicability of this approach is illustrated by screening a series of molecular single‐site catalysts which points to the importance of electrostatic interactions as well as hydrogen bonding in the functionalization of the electrode.
Facile construction of a multilayered interface for a durable lithium‐rich cathode
Authors: Xu Zhou , Yuan Yifei , Tang Qing , Nie Xiangkun , Li Jianwei , Sun Qing , Ci Naixuan , Xi Zhenjie , Han Guifang , Ci Lijie , Min Guanghui 
Published: February 2023

AbstractLayered lithium‐rich manganese‐based oxide (LRMO) has the limitation of inevitable evolution of lattice oxygen release and layered structure transformation. Herein, a multilayer reconstruction strategy is applied to LRMO via facile pyrolysis of potassium Prussian blue. The multilayer interface is visually observed using an atomic‐resolution scanning transmission electron microscope and a high‐resolution transmission electron microscope. Combined with the electrochemical characterization, the redox of lattice oxygen is suppressed during the initial charging. In situ X‐ray diffraction and the high‐resolution transmission electron microscope demonstrate that the suppressed evolution of lattice oxygen eliminates the variation in the unit cell parameters during initial (de)lithiation, which further prevents lattice distortion during long cycling. As a result, the initial Coulombic efficiency of the modified LRMO is up to 87.31%, and the rate capacity and long‐term cycle stability also improved considerably. In this work, a facile surface reconstruction strategy is used to suppress vigorous anionic redox, which is expected to stimulate material design in high‐performance lithium ion batteries.
Boosting the Ni–Zn interplay via O/N dual coordination for high‐efficiency CO2 electroreduction
Authors: Zhang Ying , Jiang Hailei , Kumar Anuj , Zhang Hongchuan , Li Zongge , Xu Tongxin , Pan Yuan , Wang Yaqun , Liu Zhiming , Zhang Guoxin , Yan Zifeng 
Published: February 2023

AbstractDesign of supportive atomic sites with a controllably adjusted coordinating environment is essential to advancing the reduction of CO2 to value‐added fuels and chemicals and to achieving carbon neutralization. Herein, atomic Ni (Zn) sites that are uniquely coordinated with ternary Zn (Ni)/N/O ligands were successfully decorated on formamide‐derived porous carbon nanomaterials, possibly forming an atomic structure of Ni(N2O1)‐Zn(N2O1), as studied by combining X‐ray photoelectron spectroscopy and X‐ray absorption spectroscopy. With the mediation of additional O coordination, the Ni–Zn dual site induces significantly decreased desorption of molecular CO. The NiZn‐NC decorated with rich Ni(N2O1)‐Zn(N2O1) sites remarkably gained >97% CO Faraday efficiency over a wide potential range of ‒0.8 to ‒1.1 V (relative to reversible hydrogen electrode). Density functional theory computations suggest that the N/O dual coordination effectively modulates the electronic structure of the Ni–Zn duplex and optimizes the adsorption and conversion properties of CO2 and subsequent intermediates. Different from the conventional pathway of using Ni as the active site in the Ni–Zn duplex, it is found that the Ni‐neighboring Zn sites in the Ni(N2O1)‐Zn(N2O1) coordination showed much lower energy barriers of the CO2 protonation step and the subsequent dehydroxylation step.
Thermally Activated Delayed Fluorescence and Room‐Temperature Phosphorescence in Materials with Imidazo‐pyrazine‐5,6‐dicarbonitrile Acceptors
Authors: Xu Pengfei , Hojo Ryoga , Hudson Zachary M. 
Published: February 2023

AbstractThree donor‐acceptor compounds based on the imidazo‐pyrazine‐5,6‐dicarbonitrile (IPDC) acceptor were synthesized. The IPDC emitters exhibit blue to near‐infrared (NIR) emission with up to 54 % photoluminescent quantum yield. 9,9‐Dimethyl‐9,10‐dihydroacridine (ACR), phenoxazine (POX), and phenothiazine (PTZ) served as electron donors. IPDC‐POX displayed NIR emission in toluene solution, while showing room‐temperature phosphorescence in the solid state. IPDC‐ACR exhibited yellow thermally activated delayed fluorescence. Interestingly, dual‐emissive behavior as well as excitation‐dependent thermally activated delayed fluorescence (TADF) was found for IPDC‐PTZ, arising from the two conformers of phenothiazine derivatives. Overall, this work describes a novel strong electron acceptor from the fusion of imidazole, pyrazine, and nitrile functional groups into one conjugated heterocycle for materials exhibiting NIR emission, TADF, and/or room‐temperature phosphorescence (RTP).
Toward a Comprehensive Understanding of Amorphous Photocatalysts: Fundamental Hypotheses and Applications in CO2 Photoreduction
Authors: Powar Niket S. , Kim Dongyun , In Su‐Il 
Published: February 2023

AbstractIn principle, photocatalytic activity can be precisely controlled with crystalline catalysts. However, an amorphous photocatalyst could be a viable candidate for CO2 photoreduction to form value‐added products. The amorphous phase is currently part of the crystalline material in several ongoing CO2 photoreduction studies. Additionally, no study indicates the amorphous material required for overall CO2 photoreduction. This perspective review article highlights fundamental assumptions that are necessary to gain insights and understand the effectiveness of amorphous photocatalysts for CO2 photoreduction. We start with basic ideas and theories about these materials, including light harvesting, variable coordination number, and the interaction of CO2 molecules with the amorphous catalytic surface. To understand the prospects of the amorphous photocatalyst, we explore machine learning with EXAFS. Furthermore, we discuss product selectivity and regeneration of photocatalysts in detail. Finally, we briefly review the work in progress on amorphous materials and compare it to that on crystalline ones.
Structural Engineering of Red Luminogens to Realize High Emission Efficiency through ACQ‐to‐AIE Transformation
Authors: Sun Hua , He Tengfei , Zhang Chuchen , Wang Shifan , Dong Liming , Li Zhao , Gu Pei‐Yang , Wang Zhe , Long Guankui , Zhang Qichun 
Published: February 2023

AbstractDeep red/near‐infrared (NIR, >650 nm) emissive organic luminophores with aggregation‐induced emission (AIE) behaviours have emerged as promising candidates for applications in optoelectronic devices and biological fields. However, the molecular design philosophy for AIE luminogens (AIEgens) with narrow band gaps are rarely explored. Herein, we rationally designed two red organic luminophores, FITPA and FIMPA, by considering the enlargement of transition dipole moment in the charge‐transfer state and the transformation from aggregation‐caused quenching (ACQ) to AIE. The transition dipole moments were effectively enhanced with a “V‐shaped” molecular configuration. Meanwhile, the ACQ‐to‐AIE transformation from FITPA to FIMPA was induced by a methoxy‐substitution strategy. The experimental and theoretical results demonstrated that the ACQ‐to‐AIE transformation originated from a crystallization‐induced emission (CIE) effect because of additional weak interactions in the aggregate state introduced by methoxy groups. Owing to the enhanced transition dipole moment and AIE behaviour, FIMPA presented intense luminescence covering the red‐to‐NIR region, with a photoluminescence quantum yield (PLQY) of up to 38 % in solid state. The promising cell‐imaging performance further verified the great potential of FIMPA in biological applications. These results provide a guideline for the development of red and NIR AIEgens through comprehensive consideration of both the effect of molecular structure and molecular interactions in aggregate states.
Nanolobatone A, An Unprecedented Diterpenoid and Related New Casbanoids from the Hainan Soft Coral Sinularia nanolobata
Authors: Liu Jiao , Li Song‐Wei , Zhao Qing‐Min , Zhang Zai‐Yong , Yao Li‐Gong , Gu Yu‐Cheng , Lan Le‐Fu , Guo Yue‐Wei 
Published: February 2023

AbstractNanolobatone A, featuring an unprecedented tricyclo[10.3.0.01,2]pentadecane carbon skeleton, along with four new polyoxygenated and four unusual endoperoxide‐bridged casbane‐type diterpenoids were isolated from the Hainan soft coral Sinularia nanolobata. The structures of the new compounds were established by extensive spectroscopic analysis, X‐ray diffraction analysis, and time‐dependent density functional theory/electronic circular dichroism calculations. A plausible biosynthetic pathway of new isolates was proposed. Bioassays revealed that nanolobatone A showed weak antibacterial activity against the Gram‐positive bacteria Streptococcus pyogenes.
A New Type of Valence Tautomerism in Cobalt Dioxolene Complexes – Temperature‐Induced Transition from a Cobalt(III) Catecholate to a Low‐Spin Cobalt(II) Semiquinonate State
Authors: Metzger Christoph , Dolai Ramapada , Reh Sabine , Kelm Harald , Schmitz Markus , Oelkers Benjamin , Sawall Mathias , Neymeyr Klaus , Krüger Hans‐Jörg 
Published: February 2023

AbstractThe synthesis and characterization of the monocationic cobalt(III) catecholate complex [Co(L‐N4tBu2)(Cl2cat)]+ (L‐N4tBu2=N,N’‐Di‐tert.‐butyl‐2,11‐diaza[3.3](2,6)pyridinophane, Cl2cat2−=4,5‐dichlorocatecholate) are presented. The complex exhibits valence tautomeric properties in solution; but, in contrast to the usually observed conversion from a cobalt(III) catecholate to a high‐spin cobalt(II) semiquinonate state, valence tautomerism of [Co(L‐N4tBu2)(Cl2cat)]+ leads to the formation of a low‐spin cobalt(II) semiquinonate complex upon raising the temperature. This new type of valence tautomerism for a cobalt dioxolene complex has been unambiguously established by a detailed spectroscopic investigation using variable‐temperature NMR, IR and UV‐Vis‐NIR spectroscopy. Determination of the enthalpies and entropies characterizing the valence tautomeric equilibria in various solutions shows that the influence of the solvent is almost exclusively entropic.
Comprehensive Investigation of Anion Species in Crystalline Li+ ion Conductor Li27−x[P4O7+xN9−x]O3 (x≈1.9(3))
Authors: Schneider Stefanie , Wendinger Eva‐Maria , Baran Volodymyr , Hatz Anna‐Katharina , Lotsch Bettina V. , Nentwig Markus , Oeckler Oliver , Bräuniger Thomas , Schnick Wolfgang 
Published: February 2023

AbstractThe Li+ ion conductor Li27−x[P4O7+xN9−x]O3 (x≈1.9) has been synthesized from P3N5, Li3N and Li2O in a Ta ampoule at 800 °C under Ar atmosphere. The cubic compound crystallizes in space group
with a=12.0106(14) Å and Z=4. It contains both non‐condensed [PO2N2]5− and [PO3N]4− tetrahedra as well as O2− ions, surrounded by Li+ ions. Charge neutrality is achieved by partial occupancy of Li positions, which was refined with neutron powder diffraction data. Measurements of the partial ionic and electronic conductivity show a total ionic conductivity of 6.6×10−8 S cm−1 with an activation energy of 0.46±0.02 eV and a bulk ionic conductivity of 4×10−6 S cm−1 at 25 °C, which is close to the ionic conductivity of amorphous lithium nitridophosphate. This makes Li27−x[P4O7+xN9−x]O3 an interesting candidate for investigation of structural factors affecting ionic conductivity in lithium oxonitridophosphates.
HighlyE‐Selective Olefin Synthesis Catalysed by Novel Quinoxalinone Photocatalyst under Visible Light Conditions
Authors: Xu Xin , Huang Jie , Gao Dandan , Wang Jiahua , Tang Xiang‐Ying , Wang Long 
Published: February 2023

AbstractIn photo‐induced olefin synthesis, the photocatalysts with high triplet energy could cause the isomerization of olefins. This study demonstrates a new quinoxalinone photocatalytic system for highly stereoselective alkenes preparation from alkenyl sulfones and alkyl boronic acids. Our photocatalyst could not convert the thermodynamically favoredE‐olefin toZ‐olefin, guaranteeing the highE‐configuration selectivity of the reaction. There is weak interaction between boronic acids and quinoxalinone according to NMR experiments, probably decreasing the oxidation potential of boronic acids. This system can be further extended to the allyl and alkynyl sulfones to give corresponding alkenes and alkynes.
Impact of the ultra‐long 48 mm drug‐eluting stent on procedural and clinical outcomes in patients with diffuse long coronary artery disease
Authors: Youn Young Jin , Jeon Ho Sung , Kim Young In , Lee Jung‐Hee , Park Young Jun , Cho Dong‐Hyuk , Son Jung‐Woo , Lee Jun‐Won , Ahn Min‐Soo , Ahn Sung Gyun , Kim Jang‐Young , Yoo Byung‐Su , Lee Seung‐Hwan , Yoon Junghan 
Published: February 2023

AbstractBackgroundDiffuse coronary artery disease (CAD) is a prognostic factor after percutaneous coronary intervention (PCI) and requires multiple overlapping stent implantations.HypothesisWe investigated the impact of ultra‐long 48 mm drug‐eluting stent (DES) on procedural and clinical outcomes in real‐world practice.MethodsPatients who underwent DES implantation for a lesion length of >40 mm were selected from a prospective registry between 2019 and 2021. Patients treated with one or more ultra‐long 48 mm DES were in the ultra‐long DES group (n = 221). The others comprised the conventional DES group (n = 428). Procedural and clinical outcomes were compared after propensity score matching (PSM). The primary endpoint was a device‐oriented composite outcome (DOCO) consisting of cardiac death, target vessel‐related myocardial infarction, and target lesion revascularization at 1‐year follow‐up.ResultsAfter PSM, 158 matched pairs of patients showed no differences in the baseline clinical and angiographic characteristics. The stent delivery failure rate, the use of guide‐extension catheter or anchor balloon technique, and the procedural success rate were similar for both groups. Approximately two‐thirds of lesions could be treated with one DES in the ultra‐long DES group. At 1‐year follow‐up, the DOCO was similar for both groups (2.5% vs. 0.6%,p = .168).ConclusionsIn daily clinical practice, ultra‐long DES implantation is as safe and effective as multiple overlapping conventional DES implants in treating diffuse long CAD. However, ultra‐long DES can reduce the number of stents. (Trial Registration: ClinicalTrials.gov Identifier: NCT02038127).
Develop medium‐ to long‐term climate information services to enhance comprehensive climate risk management in Africa
Authors: Omukuti Jessica , Wanzala Maureen Anyango , Ngaina Joshua , Ganola Phoebe 
Published: February 2023

AbstractIncreasing climate change risks in Africa, emerging from global warming and their interaction with non‐climate risks such as market, have increased the need for comprehensive Climate Risk Management (CRM) that considers both climatic and non‐climatic risks and enables actions that address the underlying drivers of vulnerability to these risks. However, comprehensive CRM requires holistic Climate Information Services (CIS), that is, CIS that balances between components focused on provision of short‐ and long‐term climate information for both local and non‐local decision makers. In this article, we ask: to what extent is CIS in Africa holistic? We review recent and ongoing CIS interventions in Africa to determine whether a balance of components between short‐ and long‐term CIS for local and non‐local decision makers is achieved for holistic CIS. We find a focus on provision of short‐term, that is, Sub‐Seasonal‐to‐Seasonal (S2S) CIS for local and non‐local decision makers, with limited focus on medium‐ to long‐term (MLT) CIS, particularly MLT CIS for local decision makers which represents the biggest gap to achieving holistic CIS in Africa. We present a supported case that ensuring holistic CIS in Africa will require a portfolio‐based approach to CIS development, particularly focusing on MLT CIS for local decision makers. We further highlight the need for integration of this MLT CIS for local decision makers into existing CIS. Achieving this will require: (a) experimentation and innovation with different CIS formats, products and timeframes to enable learning and flexibility to achieve desired goals; (b) capacity development of producers and consumers of climate information to ensure that they have the skills and expertise to understand and generate, and articulate needs and consume MLT CIS respectively; and (c) coordinated allocation of financial resources to ensure that all components of the holistic CIS are advanced.