bluuebunny/crossref_metadata_2025_split huggingface dataset:
Level of Evidence Diagnosis Skabies Berdasarkan Oxford Centre for Evidence-Based Medicine
Authors: Gunardi Keiko , Sungkar Prof Saleha , Widaty Sandra , Irawan Yudo 
Published: July 2023

Abstrak
Skabies merupakan masalah kesehatan komunitas di seluruh dunia dan penyakit ini menjadi infeksi tropis yang sering terabaikan di Indonesia. Manifestasi kulit pada skabies yang tidak khas, namun tetap digunakan sebagai dasar dalam mendiagnosis skabies dengan tambahan pemeriksaan mikroskopik langsung. Tinjauan pustaka ini membahas penegakan diagnostik skabies berdasarkan level of evidence dari berbagai pemeriksaan penunjang. Pemeriksaan penunjang yang dibahas adalah pemeriksaan langsung mikroskopik, pemeriksaan dermoskopi, dan pemeriksaan imunologi antara lain Polymerase Chain Reaction (PCR) dan Enzyme-linked immunosorbent assay (ELISA) yang mempunyai LoE 1B. Pemahaman yang tepat mengenai metode diagnosis skabies akan memberikan tata laksana serta mendukung eradikasi penyakit ini.

Abstract
Scabies become a public health burden worldwide and the most common neglected tropical skin diseases in Indonesia. However, atypical skin manifestations are frequent and the widely used diagnostic test based on microscopic examinations has limited sensitivity. This literature review discuss about diagnostic method in patient with scabies according to level of evidence. We compared the classical manifestation, the new diagnostic consensus criteria, microscopic examination, dermoscopy examination and immunological assay such as polymerase chain reaction (PCR) and Enzyme-linked immunosorbent assay (ELISA) categorized in LoE 1B. The knowledge about the diagnostic method will give an effective treatment for scabies patient and will eradicate this disease.
Vaginal Estrogen Cream in Menopausal Women Using Pessary to Reduce Bacterial Vaginosis
Authors: Hakim Surahman , Santoso Budi Iman , Surya Raymond , Kurniawan Andrew Pratama 
Published: July 2023

Vaginal estrogen cream has widely been used for vaginal atrophy in menopausal women. However, the effectiveness in preventing bacterial vaginosis (BV) in women with pessary is limited. The study aims to evaluate the effectiveness of vaginal estrogen cream in preventing bacterial vaginosis in menopausal uterine prolapse women with a pessary. A literature search was conducted on PubMed®, Scopus®, and google scholar® before May 2022 using MeSH. Two investigators searched, extracted, and appraised the evidence. The studies were appraised using the Centre for Evidence-Based Medicine, University of Oxford, randomized controlled trial appraisal tools. There were two articles appropriate to the inclusion and exclusion criteria. Both studies were valid, important and applicable to our case. The relative risk of bacterial vaginosis after locally applied vaginal estrogen was 0.91-0.92, with a number needed to treat (NNT) 63.3-186.6. Estrogen vaginal cream did not reduce the risk of BV for menopausal women with pessary in the short term; however, BV incidence is reduced in the longer term.
Hubungan Pemanfaatan E-Learning terhadap Motivasi Belajar Mahasiswa Fakultas Kedokteran Universitas Muhammadiyah Semarang
Authors: Said Nurfiyan W.U.U. , Novitasari Andra , Arfiyanti Mega P. , Romadhoni Romadhoni 
Published: July 2023

Motivasi belajar mahasiswa bersifat dinamis atau dapat berubah setiap waktu. Penurunan motivasi belajar akan berdampak terhadap prestasi akademik dan meningkatkan risiko dropout pada mahasiswa. Mahasiswa telah menjadi pemakai internet terbesar dan e-learning memiliki peluang yang besar untuk meningkatkan motivasi belajar mahasiswa. Penelitian ini bertujuan untuk mengetahui hubungan pemanfaatan e-learning terhadap motivasi belajar mahasiswa Fakultas Kedokteran Universitas Muhammadiyah Semarang. Penelitian dilakukan pada bulan Oktober 2022 dengan menggunakan metode kuantitatif dengan rancangan analitik observasional dan pendekatan cross sectional. Sampel adalah mahasiswa tahum kedua dam ketiga Fakultas Kedokteran Universitas Miuhammadiyah Semarang. Sampel dipilih menggunakan total sampling dengan kriteria inklusi dan kriteria eksklusi. Analisis data dilakukan dengan Rank Spearman. Responden memiliki pemanfaatan e-learning baik (51,9%) dan motivasi belajar tinggi (90,7%) serta terdapat hubungan yang signifikan dan korelasi positif antara Pemanfaatan e-learning terhadap motivasi belajar dengan kekuatan korelasi kuat (uji Rank Spearman,p = 0,000 dan r = 0,730). Pemanfaatan E-learning berhubungan signifikan terhadap motivasi belajar mahasiswa Fakultas Kedokteran Universitas Muhammadiyah Semarang.
Single high-dose radiation therapy and liquid fiducial markers can be used in dogs with incompletely resected soft tissue sarcomas
Authors: Ericksen Timothy , Mauldin Neal , Dickinson Ryan , Mauldin Glenna 
Published: July 2023

Abstract

OBJECTIVE
To evaluate the outcome and effects of single high-dose radiation therapy with the aid of liquid fiducial markers in dogs following resection of soft tissue sarcomas (STSs).

ANIMALS
36 client-owned dogs.

METHODS
Dogs with a histologic diagnosis of a grade II or III STS that underwent liquid fiducial guided single fraction, 20-Gy stereotactic radiation therapy following surgical excision of an STS between May 2017 and March 2019 were prospectively enrolled in this study. Data collected from the medical records included patient signalment, tumor-related information, treatment details, and outcome. Kaplan-Meier survival analysis was performed for overall survival time (OST) and disease-free interval (DFI). The median OST and DFI were not reached, so restricted mean OST and DFI were also calculated.

RESULTS
36 dogs were included in the study. All dogs underwent radiation therapy a mean of 36.1 days (range, 20 to 59 days) after surgery. Acute and delayed radiation toxicity effects occurred in 80.5% and 36.1% of dogs, respectively, all of which affected the skin. Tumor recurrence was noted in 24.3% of dogs with a median time to recurrence of 272 days (range, 14 to 843 days). The restricted mean OST was 1,556 days (range, 1,383 to 1,728 days) and restricted mean DFI was 1,330 days (range, 1,101 to 1,559 days).

CLINICAL RELEVANCE
The results of this study showed that administering a single 20-Gy fraction of radiation in combination with a liquid fiducial marker to treat marginally or incompletely resected STS in the absence of gross disease resulted in similar OST and DFI compared to other previously reported radiation protocols.
Potential of Paulownia Leaves Silage in Lamb Diet to Improve Ruminal Fermentation and Fatty Acid Profile − An in vitro Study
Authors: Szulc Paulina , Nowak Bogumiła , Hassan Mahmood Ul , Lechniak Dorota , Ślusarczyk Sylwester , Bocianowski Jan , Szumacher-Strabel Małgorzata , Patra Amlan Kumar , Cieslak Adam 
Published: July 2023

Abstract
Environmental impact, quality, and quantity of food products of ruminant origin (especially beef and mutton) are considered major challenges in meeting the nutritional requirements of the growing human population worldwide. Therefore, we conducted this in vitro study to explore the potential of Paulownia leaves silage to reduce the environmental impact of feedlot lamb production and improve ruminal fatty acids (FAs) profile by influencing ruminal biohydrogenation. In the present study, Paulownia leaves silage (PLS) and alfalfa silage (AAS) were mixed in a proportion of 1:0 (Control, PLS 0%), 0.75:0.25 (PLS 25%), 0.5:0.5 (PLS 50%), 0.25:0.75 (PLS 75%) and 0:1 (PLS 100%) on dry matter basis in the lamb diet. The experimental findings demonstrated that 100% replacement of AAS with PLS in the lamb diet significantly improved the ruminal fermentation by increasing the in vitro DM degradability (P<0.01), total volatile fatty acid (P<0.01), and propionate production (P<0.01) while reducing the acetate: propionate (A/P) ratio (P<0.01) and CH4 concentration (mM; L and Q P<0.05) and CH4 production, mM/g DM (L and Q P<0.05). Meanwhile, 100% PLS inclusion in the diet increased the total monounsaturated fatty acids (P<0.05), total unsaturated fatty acids (P<0.01) and total n-3 fatty acids (P<0.05) particularly alpha-linolenic acid (ALA; C18:3 n-3; P<0.05) in the rumen fluid after incubation. Moreover, the total saturated fatty acids concentration was reduced (P<0.01). These findings suggested that PLS could be a climate-friendly and sustainable alternative to AAS in the lamb feedlot diet for quality meat production.
Assessment of Initial Investment Strategies for Different Farm-Scale Scenarios with Economic Cost Analyses in Offshore Salmon Farming
Authors: Yigit Ümüt 
Published: July 2023

Abstract
The simulation of investment strategies with different farm-scale scenarios has been evaluated for best management plan in cage farming business for the establishment of a salmon production with either full capacity or progressive investment. Economical revenues were analyzed with business risk assessment based on operating and fixed costs for each of the four scenarios. In the theoretical model projected for the stimulation of best management plans, structural elements for the construction of an offshore Turkish salmon farm in the Black Sea were designed and investment costs for an annual production capacity of 4,000 tons were re-scaled by 25, 50 and 75% reduction, corresponding to 3,000, 2,000 and 1,000 tons per year, respectively. Economic variables of operational costs were comparatively evaluated with the revenues and annual profit conditions by sales of harvested fish. The break-even points for all investment strategies with different farm-scale scenarios were remarkably lower (on average 302,574.7 kg/year) than the harvest yields from the farms (on average 3,702,857.1 kg/year). Based on break-even points and margin of safety (MOS over 85%), all farms gained net profits with low risks in the first year, whether the farm received full investment, or initiated business with reduced investment expenditures for a gradual and progressive expansion plan. Findings of this study exhibit useful indications for farm management in understanding conditions of a stepwise establishment of business plans for salmon farming in offshore conditions.
Prebiotic effects of dietary xylooligosaccharides on fish gut microbiota, growth, and immunological parameters – A review
Authors: Gufe Claudious , Merrifield Daniel L. , Hoseinifar Seyed Hossein , Rattanarojpong Triwit , Khunrae Pongsak , Abdel-Tawwab Mohsen 
Published: July 2023

Abstract
Xylooligosaccharides (XOSs) are being explored as prebiotics in fish diets; however, their effects and modes of action have not been well evaluated. Reports have shown that dietary XOS has the potential to improve the proliferation of beneficial gut microbes, and their metabolites, and enhance disease resistance in several fish species. In contrast, other studies report no substantial changes in immune and growth parameters compared to control groups. Like all prebiotics, the mode of action of XOS is based on their selective stimulation of beneficial gut microbiota, which will outcompete and prevent pathogen proliferation in the gut, and produce metabolites that modulate host immune responses. The reports of improved growth performance of XOS fed fish may be due to improved intestinal microbiome, enhanced glycolysis activity and elevated gastrointestinal enzymatic activities. Dietary XOSs have different effects on fish performance depending on the fish species and the structure of XOSs (degree of XOS polymerization and substitution). Nevertheless, further research is essential to determine the optimal dosage, degree of polymerization, and substitution levels required to improve each fish species’ gut health and growth performance. This review highlights the prebiotic effects of XOSs, their mechanism of action, and knowledge gaps.
Dandelion Root Extract in Trout Feed and its Effects on the Physiological Performance of Oncorhynchus mykiss and Resistance to Lactococcus garvieae Infection
Authors: Köse Özay , Karabulut Huriye Ariman , Er Akif 
Published: July 2023

Abstract
In this study, we investigated the dietary effects of dandelion root extract (DRE) on growth performance, body composition, serum biochemical parameters, intestinal and liver histology, and fish resistance against Lactococcus garvieae infection in the rainbow trout. In total, 540 rainbow trout fry (22.05±1.740 g and 13.03±0.470 cm) were used. Six experimental groups (control, 2.5 mL/kg (DRE-1), 5 mL/kg (DRE-2), 10 mL/kg (DRE-3), 20 mL/kg (DRE-4), and 40 mL/kg (DRE-5) dandelion root extract) with three replicates were formed. In each tank, 30 fish were placed and fed for 90 days, and the volume of water was adjusted to 80 L with a flow-through system. The results showed that the final fish weight, weight gain, specific growth rate, protein efficiency ratio, and protein deposition rate were significantly higher in the DRE-4 group, while the feed conversion ratio and fat deposition ratio were significantly lower compared to that in the control group (P<0.05). The viscerosomatic index and the hepatosomatic index decreased in the experimental groups depending on the concentration of the extract used, while the condition factor was higher than that in the control (P<0.05). The DRE significantly decreased glucose, cholesterol, triglyceride, low-density lipoprotein, alanine aminotransferase, and aspartate aminotransferase levels in blood serum in the fish from the experimental groups, but it significantly increased high-density lipoprotein, alkaline phosphatase, and total protein levels (P<0.05). Similarly, the DRE positively affected intestinal histology by increasing the stratum compactum, submucosa, lamina propria, villi length, villi width, absorption area, tunica muscularis thickness, mucosal folds, and goblet cell count. In the liver, depending on the high-fat diet (crude lipid = 20%), vacuolization areas, hepatocellular degeneration areas, apoptotic hepatocyte nucleus, and necrotic areas recorded in the control group decreased or even disappeared completely in the extract groups. The results of the challenge test showed that adding 2.5 mL/kg of the DRE to the feed positively affected the disease resistance against Lactococcus garvieae infection. The results of the quadratic polynomial regression showed that an average level of 23.91±1.048 mL/kg of DRE would be suitable for optimum fish growth.
Strategies for promoting sustainable aquaculture in arid and semi-arid areas – A review
Authors: Khanjani Mohammad Hosein , Sharifinia Moslem , Hajirezaee Saeed 
Published: July 2023

Abstract
Starvation and malnutrition are one of the most destructive problems faced by the poor and needy in the world. With the world population expected to increase by 9.7 billion by 2050, there are growing concerns about the long-term sustainability of many existing food production systems to meet future needs for food. Aquaculture is one of the important sources of food supply, the development of which is of great importance as an important weapon in the global fight against malnutrition and poverty, especially in developing countries and arid and semi-arid regions of the world. In recent decades, aquaculture has dominated all sectors of livestock production in terms of growth and increasingly contributes to food security, poverty reduction, job creation and sources of income. It is important to follow sustainable development goals to increase aquaculture production. Climate change is currently affecting food security through increasing temperature and decreasing rainfall, especially in arid and semi-arid regions. Food security is a global concern and access to affordable, nutritious, safe and properly cultivated food is one of the most important issues globally. The main emphasis in the development of aquaculture in arid and semi-arid areas is the use of new technologies based on water saving, such as biofloc technology (BFT), integrated multi-trophic aquaculture system (IMTA) and recirculating aquaculture systems (RAS). In this study, the importance of aquaculture as a sustainable source of food production in arid and semi-arid regions is discussed.
Mineralogy and Р-T conditions for the formation of metasomatic rocks of the Voznesenskoye gold deposit (Southern Urals)
Authors: Znamensky S. E. 
Published: July 2023

Research subject. Mineral associations, their chemical composition, and formation conditions of metasomatic rocks of the Voznesenskoye gold deposit located in the area of the Main Ural Fault in the Southern Urals.Methods. The chemical composition of minerals was studied using a Tescan Vega Compact scanning electron microscope equipped with an Oxford Instruments Xplorer 15 energy-dispersive analyzer. The formation P-T parameters were estimated using a chlorite geothermometer and a dolomite-calcite geothermobarometer.Results and conclusions. Two types of metasomatic rocks were identified: 1) propylites, which make up the outer zones of the metasomatic aureole, and 2) beresite-listvenites, common in its inner parts and hosting gold mineralization. The main propylite minerals were amphibole, orthoclase, albite, and ripidolite. Amphibole is represented by two generations, with the early generation comprising magnesian and actinolite hornblende and the late generation comprising actinolite. The crystallization temperature of ripidolite (307–313°С) corresponds to the temperature range of formation of propylites of the albite-actinolite facies. Beresite-listvenites (association: quartz, albite, chlorite, white mica, and carbonate) were formed at a temperature of 255–338°C and a pressure of 0.48–0.72 kbar. Gold ore mineralization was concentrated in the highest temperature zones of the halo of beresite-listvenite alterations. Such temperature conditions existed in dikes and their exocontact zones disturbed by ruptures. Light mica in beresite-listvenites is represented by sericite and phengite, and carbonate is a paragenesis of calcite and dolomite-ankerite. According to the composition and formation period, chlorite is differentiated into early ferruginous ripidolite and late pycnochlorite, depleted in Fe and enriched in Si, which is probably associated with a decrease in temperature during mineral formation and an increase in the activity of sulfide sulfur in the fluid. Along with an increase in the distance from the ore bodies, pycnochlorite exhibits greater contents of Si and lower contents of AlIV. The observed changes in the pycnochlorite composition are related to a decrease in temperature. The research results indicate the formation of the Voznesenskoye deposit under mesothermal conditions.
Sifat Fisis dan Mekanis Papan Partikel Serbuk Batang Pisang dan Kulit Buah Kakao Bertulang Ayaman Lidi Kelapa
Authors: Zul Adha Dendy Kurniady , Mora Mora 
Published: July 2023

Penelitian tentang pembuatan komposit dari serbuk batang pisang dan kulit buah kakao bertulang anyaman lidi kelapa terhadap sifat fisis dan mekanis papan partikel perekat resin epoksi telah dilakukan. Sifat fisis yang diuji meliputi densitas, kadar air, dan daya serap air. Sementara pengujian sifat mekanis meliputi kuat lentur dan kuat tekan. Papan partikel dibuat dengan memvariasikan komposisi partikel serbuk batang pisang dan kulit buah kakao yaitu 70%:0%, 50%:20%, 35%:35%, 20%:50%, 0%:70% dengan kadar resin epoksi 30%. Proses awal pencampuran serbuk batang pisang, serbuk kulit buah kakao, resin epoksi serta katalis. Bahan dibagi menjadi dua adonan dan dimasukan ke dalam cetakan besi ukuran 12 cm x 8 cm x 2 cm dan anyaman lidi kelapa sebagai pembatas antara dua adonan.Â Cetakan dikempa dengan tekanan kempa sebesar 3000 kg pada suhu 180oC selama 10 menit. Hasil uji sifat fisis menunjukan bahwa papan partikel termasuk papan partikel berkerapatan tinggi dengan nilai densitas di atas 9 g/cm3. Berdasarkan kadar air dan daya serap airnya memenuhi ketentuan SNI 03-2105-2006. Untuk nilai kuat lentur (MOE) belum memenuhi standar sedangkan nilai dari kuat tekan (MOR) sudah memenuhi standar SNI 03-2105-2006. Variasi massa terbaik pada pembuatan papan partikel serbuk batang pisang 20% dan serbuk kulit buah kakao 50%.
Identifikasi Pencemaran Logam Berat dan Hubungannya dengan Suseptibilitas Magnetik pada Sedimen Sungai Batang Agam Segmen Kota Bukittinggi
Authors: Aprianto Mayank , Afdal Afdal 
Published: July 2023

Kandungan logam berat pada sedimen sungai Batang Agam segmen Kota Bukittinggi telah diidentifikasi. Sampel sedimen diambil pada aliran sungai sepanjang 3 km pada Â 6 titik sampel. Enam sampel yang diambil kemudian di uji XRF untuk mengetahui kandungan logam beratnya. Hasil uji XRF menunjukan bahwa sampel mengandung logam berat Cr, Mn, Fe, Ni, Zn, Cu, As dan Pb. Konsentrasi rata-rata logam berat pada sedimen Sungai Batang Agam sudah melebihi ambang batas yang di tetapkan, yaitu Cr (206,6 ppm), Mn (3646,6 ppm), Fe (27298 ppm), Ni (83,3 ppm), Zn (4058,3 ppm), Cu (621,6 ppm), As (51,6 ppm) dan Pb (530 ppm). Hal ini mengindikasi bahwa sedimen Sungai Batang Agam segmen Kota Bukittinggi tercemar logam berat. Perbandingan kandungan logam berat antara titik S1 (hulu) dengan S15 (hilir) diketahui sungai sudah tercemar saat memasuki Kota Bukittinggi namun terdapat beberapa kandungan logam yang meningkat setelah melewati Kota Bukittinggi dengan kenaikan sekitar 60-80% dari nilai ambang batasnya.
Rancang Bangun Pembangkit Listrik Tenaga Ombak Berbasis Piezoelektrik dengan Modul Charging TP5100 pada Bangunan Groin Pemecah Ombak Pantai Padang
Authors: Shaputra Chahyo , Rasyid Rahmat 
Published: July 2023

Telah dilakukan rancang bangun pembangkit listrik tenaga ombak berbasis piezoelektrik dengan modul charging TP5100 pada bangunan groin pemecah ombak pantai Padang. Alat yang dirancang terdiri dari sensor piezoelektrik jenis Polyvinylidene DiflourideÂ (PVDF), dioda 1N4007, sensor tegangan, arduino UNO R3, LCD 16x2 dengan modul I2C, baterai lithium dan modul charging TP5100. Sensor piezoelektrik mengkonversi energi mekanis dari ombak menjadi energi listrik dengan arus AC yang disearahkan menjadi arus DC dengan rangkaian penyearah gelombang penuh 1N4007 kemudian dideteksi oleh sensor tegangan, ditampilkan pada LCD dan disimpan pada baterai lithium melalui modul TP5100. Groin mempengaruhi besar gaya mekanis ombak, semakin panjang groin, maka akan semakin besar gaya mekanis yang dibawa ombak saat mengenai piezoelektrik sehingga menghasilkan tegangan yang lebih besar, begitu sebaliknya. Tegangan rata-rata maksimum yang dihasilkan sebesar 2.75 volt DC, dengan daya 45,83 mW.Â Alat yang dirancang mampu menghasilkan energi listrik ketika sistem dikenai hantaman ombak laut pada bangunan groin pantai Padang.Kata kunci: piezoelektrik, TP5100, tegangan, groin, ombak laut, tegangan.
Sistem Informasi Tugas Akhir Berbasis Web di Jurusan Teknik Informatika Universitas Trisakti
Authors: Yunda Dwi , Syaifudin  , Sari Syandra 
Published: July 2023

The Department of Informatics has requirements for earning a Bachelor's degree, namely the Final Project. The Final Project is a research paper that must be written for students. However, the process of implementing the final project is still managed manually so problems occur on a regular basis. To avoid further issues, the author conducted research on the Information Systems of the Final Project. This system would not be integrated into the primary system of the university. There was only the Final Project 1 process in the implementation, consisting of a proposal and results seminars. This study aimed to create an Information system of Online Final Project for students who want to take Final Project 1 or those who are taking Final Project 1.
This study used the waterfall method which consisted of requirements, design, implementation, and evaluation. In the analysis and design, this study used PHP programming and a MySQL database server. The function test on the application was used to generate the test results. The Final Project Information System application would be used by the admins, students, lecturers (supervisors and examiners), and the final project coordinators.