bluuebunny/crossref_metadata_2025_split huggingface dataset:
Smartphone addiction and its impact on quality of sleep and academic performance among nursing students. Institutional based cross-sectional study in Western Rajasthan (India)
Authors: Kalal Nipin , Sabari Vel N , Angmo Sonam , Choyal Sukhi , Bishnoi Sunaina , Dhaka Subeeta , Rulaniya Suman , Banswal Surbhi 
Published: July 2023

Objective. To explore the smartphone addiction and its impact on quality of sleep and academic performance among the nursing students.
Methods. A descriptive cross-sectional study was conducted among the nursing students (n=160) in tertiary care teaching hospital in western Rajasthan (India) by using standardized Smartphone Addiction Scale Short Version (SAS-SV), the quality of sleep was assessed by standardized Pittsburg’s Sleep Quality Index scale (PSQI) and academic performance was assessed by self –made Academic Performance Scale.
Results. In this study 38.1 % students were having moderate smartphone addiction. The smartphone addiction is directly associated with hours daily spend on smartphone (p < 0.001), time check smartphone after wake up in the morning (p < 0.001), and frequency of smartphone pickups in a day (p=0.003) of students. The quality of sleep is inversely associated with duration of smartphone use (p=0.004), hours daily spend on smartphone (p=0.002), time check smartphone after wake up in morning (p=0.010), of students The academic performance is significantly associated with hours daily spend on smartphone (p=0.003), time check smartphone after wake up in morning (p=0.001), and frequency of smartphonepickups in a day (p=0.015) of students.
Conclusion: A high proportion of nursing students have moderate smartphone addiction. This addiction was associated with an increased risk of poor sleep quality and poor academic performance. Educational activities on the healthy use of smartphones are needed in the studied group.
Family integrated care: new perspectives for neonatal care
Authors: Bueno Mariana , Vieira Ana Claudia Garcia , Bacchini Fabiana 
Published: July 2023

Over the years, the highly technological environment of the Neonatal Intensive Care Units (NICUs) has allowed the survival of increasingly more premature and sick newborn infants. In parallel, physical distancing increased between hospitalized infants and their families, culminating with parents having restricted access to their children, limited to few daily hours of contact and interaction. However, this separation can negatively influence the recovery and development of the newborns and infants who remain hospitalized for extended periods of time. It is currently known that parents play a critical role in promoting positive health outcomes during hospitalization and after hospital discharge of these newborn infants.
Human Life as a Priority Object of Protection under Criminal Law
Authors: Kochoi S. M. 
Published: July 2023

The author of the paper proceeds from inviolability of the premise that a person’s life presides the hierarchy of values protected by criminal law. Recognition and actual consolidation of this provision is one of unconditional achievements adopted in the Criminal Code of the Russian Federation of 1996. However, a myriad of additions and amendments made to the Criminal Code of the Russian Federation after it entered into force raises the question of whether they do not call into question the postulate of human life as a priority object of criminal protection?To answer this question, the paper substantiates the thesis that decisive indicators of assessing a person’s life as the most important object of criminal law protection take the place in the system of the Special Part of the Criminal Code of the Russian Federation, which the legislator has assigned to infringeent on life (primarily murder), and the grounds that are established by the General Part of the Criminal Code of the Russian Federation for imposing the strictest of all types of punishment (life imprisonment or death penalty). Based on these indicators, initially established in the Criminal Code of the Russian Federation, the author concludes that at the time of its entry into force, a human life was really at the top of the system of values and goods protected by the Criminal Code. However, at present this conclusion cannot be considered indisputable, since the Criminal Code of the Russian Federation has introduced other norms where the sanctions are stricter than the sanctions of the norm on murder, and the grounds for the appointment of life imprisonment now include not only encroachments on human life. The author proposes to construct sanctions norms — both newly introduced and already existing — in such a way that no crime can be punished more severely than murder. In addition, the author proposes to abandon the legislative and law enforcement practice of absorbing murder by qualifying elements of other crimes, bearing in mind that they should be qualified only cumulatively.
Public Danger: Problems of Definition
Authors: Ondar A.‑B. S. 
Published: July 2023

A crime becomes a crime when the public danger is defined properly. The concepts of «public» and «danger» form the basis of the concept of public danger, which is an indicator for the criminalization and decriminalization of an act. The paper provides a lexical and doctrinal analysis of the concept of public danger, its social significance and the problems of developing criteria for its definition in relation to the benefits and human rights. The historical analysis of public danger, its relevance and the need to enshrine it in the current Criminal Code of the Russian Federation require a more careful consideration of this concept. It is not only public danger that must be established in the criminal law, but the criteria for distinguishing between its degree and nature must also be clearly formulated. Timely and proper definition of public danger allows you to adequately treat criminalization and decriminalization without prejudice to society. The paper proposes the author’s definition of public danger.
Congenital organic hyperinsulinism associated with a variant in the <i>ABCC8</i> gene. Description of a family case
Authors: Ivanov Dmitry O. , Ditkovskaya Lilaya V. , Turkunova Mariia E. , Suspitsin Evgeny N. 
Published: July 2023

Hypoglycemia is the most common metabolic disorder occurring in early childhood, which can be the first, and sometimes the only symptom of a whole range of diseases. Etiology determines the characteristic clinical features of the course of hypoglycemic syndrome. Diagnosis is complicated by the fact that the clinical manifestations of hypoglycemia are variable and little specific. The main cause of persistent hypoglycemia in children of the first years of life is congenital hyperinsulinism.
Congenital hyperinsulinism is a hereditary disease characterized by inadequate hypersecretion of insulin by beta cells of the pancreas. Manifesting as a rule in the neonatal period, congenital hyperinsulinism is a great threat, both in terms of survival of patients with late diagnosis, and in terms of the risks of severe neurological complications with inadequate therapy of emerging hypoglycemia.
The article describes a family case of congenital organic hyperinsulinism associated with a rare heterozygous mutation in the ABCC8 gene, the early diagnosis of which allowed avoiding severe complications of the disease and timely prescribing adequate treatment. The clinical variability of the course of the disease in related patients was shown, which required a personalized approach to diagnosis and treatment.
Thus, early detection of hypoglycemia, clarification of its etiology, including with the help of molecular genetic analysis, timely drug therapy and monitoring of the state of carbohydrate metabolism, are important aspects in the treatment and supervision of patients with congenital hyperinsulinism and the prevention of severe neurological complications in them.
Effect of low thoracic erector spinae block on postoperative pain management in patients undergoing lumbar microdiscectomy surgery
Authors: BİRİCİK Ebru , KARACAER Feride , LAFLI TUNAY Demet , ILGINEL Murat Türkeün , OKTAY Kadir , ÜNLÜGENÇ Hakkı , GÜNEŞ Yasemin 
Published: July 2023

Purpose: Lumbar disk hernia is very common reason for spinal surgery and usually treats with surgical interventions. The primary aim of this randomized controlled study was to determine the effect of low thoracic ultrasound guided erector spinae plane (ESP) block on postoperative pain management in lumbar microdiscectomy surgery.
Materials and Methods: Totally 42 adults scheduled for elective lumbar microdiscectomy surgery and assigned into two groups as Group ESP and Group Control. Anesthesia was induced with propofol 2mg/kg, rocuronium 0.6 mg/kg, fentanil 2µg/kg and maintained with total intravenous anesthesia (propofol 4-8 mg/kg/h and remifentanil 0.03-0.05 µg/kg/min), N2O/O2 mixture %60/40 for all patients. When patients were positioned at prone, ESP or sham block performed bilaterally. ESP performed with bupivacain 0.5% 15 mL+lidocain 2% 5 mL in ESP group and saline 20 mL for sham group at the T10 level of spine. The postoperative analgesia provided with morphine 0.1 mg/kg intravenously and diclofenac Na 75 mg intramuscularly at last 30 minutes of surgery for all patients. Postoperative visual analog scale (VAS) scores, meperidine requirements and patients’ satisfaction were recorded.
Results: There were significant differences between Group ESP and Group Control in meperidine requirement, VAS scores at rest and leg movement and patients’ satisfaction. Time to first analgesic need was median 62.5 min (interquartile range 5-180) in Group ESP and median 7.50 min (interquartile range 5-10) in Group Control.
Conclusion: ESP can significantly reduce postoperative pain scores (VAS at rest and leg movement), meperidine requirement and can provide better patients’ satisfaction, postoperatively.
Evaluation of sternocleidomastoid muscle cutaneous silent period in patients with cervical dystonia
Authors: KIR Hasan Hüseyin , YÜRÜTEN ÇORBACIOĞLU Betigül , TOKGÖZ Osman Serhat 
Published: July 2023

Purpose: The aim of this study to examine the in changes inhibitory interneurons of the brainstem, which are likely to be involved in pathophysiology of cervical dystonia, using the cutaneous silent period(SP) method which is an inhibitor reflex.
Materials and Methods: SP latency and interval values were obtained from bilateral sternocleidomastoid (SCM) muscles of individuals in 20 patients with cervical dystonia and 25 healthy volunteers using superficial electrodes. SP parameters obtained were compared within and between groups. Furthermore, intra-individual correlation analysis was performed for SP parameters from bilateral SCMs of the individuals in both groups.
Results: The mean age of the patients participating in the study was 49.3 ± 14.7, and the control group was 48.0 ± 13.7. There was no statistically significant difference between the two groups in terms of age and gender. No significant difference was found in the comparison of SP parameters both within and between groups. There was a strong intra-individual correlation between SP latencies of bilateral SCMs of both patient and control groups. It was determined that the strongly positive intra-individual correlation between SP intervals also continued in the control group, whereas at patient group disappeared.
Conclusion: The loss of correlation between bilateral SCM SP durations in the dystonia group indicates that the abnormality in interneuron connections, which is thought to be present in dystonia, may actually be a loss of order. This “disorganization” may explain the discrepancies in the results of cutaneous SP studies in dystonia patients.
A new prognostic index associated with pathological complete response in rectal cancer
Authors: YETİŞİR Abdullah Evren , BÜYÜKŞİMŞEK Mahmut , OĞUL Ali , ÇİL Timuçin , BOZKURT DUMAN Berna 
Published: July 2023

Purpose: Approximately half of rectal cancer cases are diagnosed at a locally advanced stage. It is important to identify biomarkers that can predict pathological complete response in patients undergoing surgery following neoadjuvant chemoradiotherapy.
Materials and Methods: This retrospective study included 205 patients with locally advanced rectal cancer who underwent surgery and adjuvant chemotherapy following neoadjuvant chemoradiotherapy. Inflammatory biomarkers were assayed in the complete blood count before neoadjuvant therapy.
Results: A pathological complete response was detected in 20.5% of the patients. The neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, and pan-immune inflammation value were significantly lower in the pathological complete response (+) group than in the pathological complete response (-) group. The cut-off of the pan-immune inflammation value was ≤ 331.2, and this parameter had the best diagnostic performance of 90.4%.
Conclusion: Neoadjuvant chemoradiotherapy followed by surgery and adjuvant chemotherapy remains the standard treatment approach for rectal cancer. Since pathological complete response improves oncological outcomes, it is important to identify biomarkers that can predict pathological complete response in rectal cancer
Analysis of ease and usefulness of using google sheets in accounting assignment with technology acceptance model approach
Authors: Dharojah Eka Putry Wahyuning , Sedyati Retna Ngesti , Tiara Tiara 
Published: July 2023

Abstrak: Pelaksanaan kegiatan pembelajaran akuntansi saat ini sudah mulai dilakukan dengan berbantuan aplikasi. Aplikasi yang digunakan sebaiknya adalah aplikasi yang dapat diterima oleh seluruh siswa karena hal tersebut akan memudahkan siswa dalam memahami materi pembelajaran. Penelitian deskriptif kuantitatif ini dilakukan dengan tujuan untuk mendeskripsikan tingkat penerimaan siswa terhadap penggunaan aplikasi Google Sheets dalam pembelajaran akuntansi. Sampel yang digunakan adalah sebanyak 143 siswa yang diambil menggunakan teknik sampel jenuh. Metode pengumpulan data adalah menggunakan angket, wawancara, serta dokumentasi yang kemudian dianalisis dengan teknik deskriptif persentase. Hasil penelitian menunjukkan bahwa siswa dapat menerima penggunaan aplikasi Google Sheets sebagai alat bantu mengerjakan tugas akuntansi karena aplikasi ini dinilai mudah dan bermanfaat untuk digunakan. Hal ini telah menyebabkan perolehan hasil belajar siswa menjadi maksimal. Dengan demikian, dapat disimpulkan bahwa penerimaan yang baik terhadap penggunaan suatu alat atau media pembelajaran akan memudahkan dalam pencapaian tujuan pembelajaran.Abstract: The implementation of accounting learning activities has now begun to be carried out with the help of applications. The application used should be an application that can be accepted by all students because this will make it easier for students to understand the learning material. This quantitative descriptive research was conducted with the aim of describing the level of student acceptance of the use of the Google Sheets application in accounting learning. The sample used was 143 students taken using the saturated sample technique. Data collection methods were by questionnaires, interviews, and documentation, which were then analyzed using percentage descriptive techniques. The results of the study show that students can accept the use of the Google Sheets application as a tool for doing accounting assignments because the application is considered easy and useful to use. This has led to the acquisition of student learning outcomes to be maximized. Thus, it can be concluded that good acceptance of the use of a learning tool or media will facilitate the achievement of learning objectives.
Results of Implantation of a New Hydrophobic Acrylic Monofocal Intraocular Lens in a Preloaded Injector
Authors: Pershin K. B. , Pashinova N. F. , Tsygankov A. Yu. , Kosova I. V. 
Published: July 2023

Purpose. To evaluate clinical and functional results of implantation of a new hydrophobic acrylic monofocal IOL in a preloaded injector.Methods. The prospective study included 60 patients (66 eyes) after Hoya iSert® 250/251 IOL implantation (31 patients, 35 eyes, group 1) and a new Hoya Vivinex Multisert® XY1-SP IOL (29 patients, 31 eyes, group 2). The mean age was 75.1 ± 7.9 years. The mean follow-up period after surgery was 3.1 ± 0.4 months. IOL viscoimplantation was performed in 100 % of cases in group 1, in group 2 — in 45.1 % of cases, and in 54.9 % — hydroimplantation was performed. Intraoperatively, the size of the corneal incision was measured with a ruler before and after IOL implantation. IOL optic power was calculated with SRK/T and Barrett Universal formulas. In the postoperative period, surgically induced astigmatism was assessed.Results. In both groups, there was a statistically significant (p < 0.05) increase of UCDVA from 0.28 ± 0.09 in the preoperative period to 0.70 ± 0.17 3 months after surgery in group 1 and from 0.24 ± 0.10 in the preoperative period to 0.84 ± 0.18 3 months after surgery in group 2. Slightly lower values of UCDVA in group 1 may be associated with a higher level of SIA in this group. Similar dynamics were shown for the BCDVA (from 0.52 ± 0.21 before surgery to 0.95 ± 0.19 after 3 months of follow-up in group 1 and from 0.55 ± 0.20 before surgery to 0.98 ± 0.21 after 3 months of follow-up in group 2). No differences were found between the studied groups. After IOL implantation, there was an increase in incision size to 2.40 ± 0.12 mm in group 1 and 2.10 ± 0.08 mm in group 2 (p = 0.04). In group 1, the mean SIA after 3 months of observation was 1.10 ± 0.16 D and in group 2, 0.48 ± 0.07 D (p = 0.0007).Conclusion. This study presents the first domestic experience with the implantation of a new monofocal hydrophobic acrylic Hoya Vivinex IOL in a Multisert® preloaded injector. A comparative analysis of implantation results with monofocal Hoya 250/251 IOLs in an Isert® injector was performed. The advantage of the new IOL implantation in reducing the incidence of surgically induced astigmatism was shown.
The Influence of Glaucoma as a Comorbidity on Cytokine Expression in Aqueous Humor of Patients with Fuchs Endothelial Corneal Dystrophy and Bullous Keratopathy
Authors: Fisenko N. V. , Demura T. A. , Osipyan G. A. , Avetisov K. S. 
Published: July 2023

Purpose: to evaluate the effect of primary open-angle glaucoma (POAG) as a comorbidity on cytokine expression in aqueous humor (AqH) of patients with Fuchs endothelial corneal dystrophy (FECD) and bullous keratopathy (BK).Patients and methods. In this prospective consecutive case study 58 patients (58 eyes) were divided into 2 main groups. Group 1 (22 patients with FECD) included 11 patients with coexisting POAG II–IIIA (group 1a) and 11 patients without ocular comorbidity (group 1b). Group 2 (28 patients with BK) consisted of 19 patients with coexisting POAG II–IIIA (group 2a) and 9 patients without ocular comorbidity (group 2b). Group 3 (control) included 8 patients with cataract. The patients of groups 1 and 2 underwent endothelial keratoplasty. Intraoperatively obtained recipients’ Descemet’s membranes (DMs) were investigated histologically (hematoxylin/eosin staining). A total of 58 AqH samples were collected from consecutive patients who underwent endothelial keratoplasty (groups 1a, 1b, 2a, 2b) or cataract surgery (controls). The AqH levels of cytokines (IL-1β, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12 (p70), IL-13, IL-17, G-CSF, GM-CSF, IFN-γ, MCP-1, MIP-1β and TNF-α) were compared among the groups.Results. Clinical diagnoses of FECD (group 1) and BK (group 2) were confirmed by the results of morphologic study. The levels of IL-8, MCP-1, IFN-γ were significantly higher in AqH samples from FECD and BK groups (regardless of the presence or absence of POAG) compared with the controls. IL-6 level was significantly elevated in FECD with coexisting POAG (group 1a) and BK (groups 2a and 2b) than in the controls. The influence of POAG on the local inflammation in FECD and BK is confirmed by the increased level of MIP-1β and the low concentration of GM-CSF compared with the controls. Among BK eyes (groups 2a and 2b), POAG as a comorbidity (group 2a) was associated with decreased level of IL-12. FECD with coexisting POAG was characterized with lower level of IL-13 in AqH than in the controls.Conclusions. POAG as a comorbid pathology in patients with FECD leads to high immune response mediated by cytokines expression. BK regardless of coexisting POAG is associated with severe local immune inflammation.
Excimer Laser Correction of Myopia in Patients with Visually Intense Work — Is It Necessary to Determine the Form of Accommodative Asthenopia?
Authors: Belikova E. I. , Gatilov D. V. , Ovechkin I. G. , Eskina E. N. 
Published: July 2023

Рurpose — to study the frequency of occurrence of various forms of accommodative asthenopia (AA) in patients with visually stressful work (VSW) with different degrees of myopia planning LASIK.Methods. As part of the preoperative examination, 300 patients with VSW were under observation. There were three groups of equal age and gender, corresponding to weak (up to 3.0 diopters, 100 patients), moderate (3.25–6.0 diopters, 100 patients ) and high (6.25–8.0 diopters, 100 patients) degrees of myopia. All patients underwent objective accommodation using the Righton Speedy-I device (Japan) with further calculation of the coefficient of microfluctuations of the ciliary muscle of the eye (KMF). Diagnosis of the type of AA was carried out according to the following indicators: with KMF less than 53.0 rel. un. — asthenic form of accommodative asthenopia (AFAA), pathology; at KMF from 53.0 to 58.0 rel. — norm; at KMF more than 58.0 rel.un. — Habitual Excessive Tension of Accommodation (HETA), pathology.Results. The incidence of AA (any form) was 51–57 % and weakly depended on the degree of myopia. A significant increase (compared with the literature data) in patients with AA according to the results of this work is due to the following factors: the examination of patients exclusively with VSW, who daily perform professional visual activity at the time of the examination, as well as a wide (24–34 years) the age range of the subjects. The probability of occurrence of HETA and AFAA is quite comparable and amounted to 29–36 % and 21–23 %, respectively. The obtained results are illustrated by typical accomodograms. Conclusion: the high incidence of both forms of AA actualizes further research aimed at assessing the dynamics of the state of the accommodative system of the eye after excimer laser surgery for myopia, as well as the development of a method for correcting AA, taking into account a personalized approach that allows performing the correct diagnosis of various forms of AA (HETA, AFAA), which, ultimately, will provide adequate treatment from the position of choosing both the actual method (physical factor) and the required optical, amplitude and time parameters of exposure.