bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE ROLE OF THE EXERCISE PROFESSIONAL IN THE SUPERVISED VERSUS TELEREHABILITATION EXERCISE PROGRAMS FOR MULTIPLE SCLEROSIS (STEP FOR MS) TRIAL
Authors: Born Kathryn A. , Neal Whitney , Ng Alexander V. , Backus Deborah , Motl Robert W 
Published: January 2023

https://youtu.be/itqMuZmn70Q

BACKGROUND
The STEP for MS trial was designed and delivered by a team of medical and rehabilitation professionals with a key player being the exercise professional (EP). Our purpose is to showcase the role of the EP and methods for standardized, safe and effective exercise and behavior change intervention.

DESIGN
Site principal investigators who designed the intervention and implementation plan were physical medicine and rehabilitation doctors, physical therapists and kinesiologists with expertise in MS and exercise programming. The interventional EP were site staff members with varied backgrounds in delivering exercise programming to people with MS. Professional titles include personal trainer, exercise specialist, clinical exercise physiologist, graduate teaching assistant, research associate, clinical integration and research coordinator. Interventionalists had little to no prior experience using the theory-based behavior change strategies employed in the trial.

METHODS
To accommodate differences in EP backgrounds and expertise, standardized training on behavior change principles and exercise prescription was required. Weekly booster meetings were held via Zoom to discuss participant progress, challenges and identify solutions and modifications to the intervention while maintaining trial fidelity. Supporting materials like exercise training manuals, scripts, newsletters, logbooks and calendars were used by EPs to deliver the intervention. EPs deployed their unique skills and training to provide guidance on exercise program progression, exercise technique modification and behavior change strategies to participants. EPs and participants mutually decided on the trajectory of exercise progression based on experiences during the first 2 standardized weeks. The trajectories differed in the rate of progression with all participants meeting the exercise guidelines of 30 minutes of aerobic exercise and 5–10 strength exercises consisting of 1–2 sets, 10–15 repetitions targeting lower body, upper body, and core musculature 2 days a week, by week 10 of the program. Outcome measures were transcribed by EPs in a research database.

CONCLUSION
There was a varied skillset among principal investigators and interventionalists in the STEP for MS trial which provided a well-rounded intervention to people with MS. Standardized training, trial-issued supporting materials and weekly booster meetings enabled successful and standardized program implementation across 8 sites.
Assessment of Oral Cancer: A Study in Nepal Cancer Hospital and Research Center, Harisiddhi, Lalitpur, Nepal.
Authors: Thapa Kapil , Jaiswal Puja 
Published: January 2023

Oral cancer is becoming very common and increasing day by day in Nepal. It ranks 6th in the world and 5th in Nepal among all types of cancer as of 2018. This is a hospital-based retrospective study. Required details of 128 patients who underwent surgery from 1st April 2018 to 30th October 2019 in Nepal Cancer Hospital and Research Center, Lalitpur. Data were collected age-wise, sex-wise, site-wise, and stage-wise prevalence was figured out. The data were analyzed using MS excel 2007. It was found that males were more commonly affected than females with the mean age for males at diagnosis being 53.3 years and females being 55.62 years. The tongue was the most affected site followed by GBS then buccal mucosa and RMT. Most people knew about cancer growing on them only at advanced stages.
Invisibility while under Scrutiny: Media Portrayals of White Temporary Foreign Workers
Authors: Hari Amrita , Ahmed Saher 
Published: January 2023

Background: Temporary foreign workers (TFWs) in Canada became the focus of public and media scrutiny in 2013 for allegedly replacing Canadian workers. One group of workers escaped the same scrutiny despite working in similar occupational categories—International Experience Canada (IEC) participants, primarily white, young workers from a variety of European countries, Australia, and New Zealand.Analysis: This article explores the significance of the spectre of whiteness to contemporary Canadian migration governance and employs critical discourse analysis, paying attention to the tone of select front-page coverage of the IEC program in two Canadian and two Irish news outlets.Conclusions and implications: The limited coverage of ethnically white IEC participants shielded them from the negative scrutiny experienced by racialized TFWs. “Irish” became a stand-in for the infinite variability of whiteness in Canadian nationhood.
APLICAÇÃO DO INDICADOR OVERALL EQUIPMENT EFFECTIVENESS (OEE)
Authors: Bernardelli Hélio , Regattieri Carlos Roberto 
Published: January 2023

Para as indústrias é de grande importância medir o desempenho dos equipamentos, uma vez que a forma com que estes são geridos colabora para o desempenho das empresas. o funcionamento dos equipamentos em sua maioria está relacionado a produção e a qualidade e eficiência desta determinam a sobrevivência da empresa. Este artigo tem como objetivo descrever o conceito da OEE e evidenciar um estudo de caso que traz um comparativo da medição de desempenho de duas máquinas pertencentes a uma indústria de produtos alimentícios. A metodologia utilizada foi de revisão de literatura com pesquisa no Google Acadêmico para a fundamentação teórica e pesquisa em campo em uma renomada indústria de produtos alimentícios. Os resultados encontrados apontam a importância do OEE dentro da indústria em questão, e deixam claro que conhecer o desempenho do equipamento é de grande importância para verificar a produtividade, qualidade, desempenho e disponibilidade, fatores de importância para o crescimento da empresa e manutenção da qualidade daquilo que se produz.
Entrepreneurial assistance for down syndrome children and caregivers in the DSI community
Authors: Katuruni Innas Rovino , Praptiwi Rahma Nur , Untari Sri Isti , Rahmi Iftita , Ariyanti Tika Dwi 
Published: January 2023

A vulnerable population, people with disabilities frequently face discrimination in the workplace. They frequently struggle to find employment in the formal sector because there aren't enough workplace amenities to support them and there aren't enough positions that match their skills. Because there aren't many jobs available in Indonesia for those with disabilities, starting a business is an excellent career option. This community service program aims to provide training and assistance for people with disabilities, especially people with Down syndrome and their caregiver who are members of the Down Syndrome Indonesia (DSI) community. This activity was conducted in three stages, including webinars, psychological testing to identify participants' strengths, workshops, and entrepreneurship mentoring. The results of this program were increased knowledge and skills of people with Down syndrome and their caregivers regarding interests and talents and the process of starting and developing a business. Thus, it is hoped that businesses built by people with Down syndrome and their caregivers can last a long time so that they can achieve economic independence.
Rare case of extracranial chordoid meningioma adjacent to the carotid sheath: illustrative case
Authors: Jeong Seung W. , Moran Michael , Elhamdani Shahed , Kusyk Dorian M. , Xu Chen , Gyure Kymberly , Williamson Richard 
Published: January 2023

BACKGROUND
Chordoid meningioma is a rare World Health Organization (WHO) grade 2 variant of meningioma with histological features resembling those of a chordoma. This tumor type is known for having an aggressive clinical course with a propensity for local recurrence. Most cases occur within the cranium, more specifically around the cerebral convexities. Although extracranial meningiomas of various subtypes have been documented, extracranial meningioma with a chordoid subtype is an extremely rare entity.

OBSERVATIONS
The authors herein report the case of a 51-year-old female who presented with a chief complaint of dysphagia and was found to have a neck mass abutting the carotid sheath. The patient underwent resection and final pathology results revealed a WHO grade 2 chordoid meningioma.

LESSONS
This case report demonstrates an atypical case of an extracranial chordoid meningioma adjacent to the carotid sheath. To the authors’ knowledge, this is the first reported case of a chordoid meningioma occurring within the soft tissue of the neck.
Concomitant brain abscess and spinal cord abscess in an immunocompetent teenage male: illustrative case
Authors: Virtanen Piiamaria S. , Jimenez Med Jimson D. , Horak V. Jane , Desai Virendra R. , Manaloor John J. , Raskin Jeffrey S. 
Published: January 2023

BACKGROUND
Multiple bilateral brain abscesses occur rarely in immunocompetent patients. Hematogenous spread to the central nervous system (CNS) allows suppuration and abscess formation in the privileged immune environment of the CNS; hematogenous spread to the spinal cord is extremely rare and the combination of multifocal brain abscesses and intramedullary abscesses has not been reported. This report presents a rare presentation and diagrams a treatment algorithm involving iterative minimal access surgeries and prolonged medical management.

OBSERVATIONS
The authors present a case of an 18-year-old male with numerous multifocal and bilateral intraparenchymal abscesses and a medically resistant C5 intramedullary spinal cord abscess. The symptomatic patient had a left oculomotor palsy and left hemiparesis, ultimately undergoing ultrasound-guided aspiration of abscesses in the left frontal and left cerebral peduncle. Following transient motor improvement, he evolved tetraparesis prompting spinal cord imaging and emergent ultrasound-guided needle aspiration of an occult C5 intramedullary spinal cord abscess. The patient received appropriate medical therapy, completed inpatient rehabilitation, and made a full recovery.

LESSONS
Needle- and ultrasound-guided catheter drainage of CNS abscesses should be considered for symptomatic lesions. Following the neurological examination closely is extremely important; if the expected neurological improvement is delayed or regresses, then expanded imaging is warranted.
Endovascular embolization and needle aspiration of a life-threatening cervical hematoma due to a neurofibromatosis type 1–associated arteriovenous fistula: illustrative case
Authors: Kojima Daigo , Akamatsu Yosuke , Aso Kenta , Kimura Kazuto , Matsumoto Yoshiyasu , Sato Shinpei , Kashimura Hiroshi , Kubo Yoshitaka , Ogasawara Kuniaki 
Published: January 2023

BACKGROUND
In cases of neurofibromatosis in which the bleeding source is considered strongly related to a neurofibroma, an open surgical approach could risk uncontrollable bleeding from the vascular wall infiltration by neurofibroma. The case of a neurofibromatosis type 1 (NF1)–associated arteriovenous fistula presenting with a life-threatening cervical hematoma that was successfully treated with alternative treatment is described.

OBSERVATIONS
A 68-year-old woman diagnosed with NF1 presented with sudden onset of a spontaneous right cervical mass. Neck imaging on admission showed a massive subcutaneous hematoma with tracheal deviation and abnormal vascular structure in the hematoma. Digital subtraction angiography showed that an arteriovenous fistula (AVF) fed from a vertebral artery located within the hematoma cavity was the primary source of bleeding and feeding arteries from the occipital artery to the neurofibroma. Embolization of the cervical neurofibroma, as well as the AVF, was performed to reduce the secondary risk of bleeding, and was accomplished. After endovascular treatment, needle aspiration of the cervical hematoma was performed to reduce the mass effect.

LESSONS
When performing open surgery via tissues with neurofibromatosis proliferation, uncontrollable bleeding can occur. Therefore, endovascular embolization and needle aspiration of the hematoma should be considered in this setting.
Chapter VI: David C. McClelland: The Need to Achieve
Authors: Gross Larry 
Published: January 2023

A large portion of the professional research performed by David McClelland has dealt with the nature of human motivation, and the achievement motive in particular. Many of his numerous papers, and five of the six books he has written, edited, and collaborated on, are concerned with questions of the origins and expression of human needs and motives.
David McClelland is professor of psychology and chairman of the Department of Social Relations at Harvard University. His many research activities have been complemented by a willingness to participate in administrative and advisory capacities in such bodies as the Ford Foundation, the Fulbright Advisory Panel, the Social Science Research Council, and the National Institute of Mental Health. The extent of this participation, greater than for any of the other subjects, indicates a certain consciousness or acceptance of the social responsibilities of his theoretical life that is an important characteristic of his personality. I think it is clear that the motive is not, consciously, a desire for power. I think we will see that it is rather an outgrowth of certain personal, perhaps even religious traits. A more important example of this is the fact that during the current year (1963–64) he is attempting to apply his theory to the task of improving society, by attempting to actually stimulate the need for achievement in the populations of underdeveloped nations. Many of his numerous papers, and five of the six books he has written, edited, and collaborated on, are concerned with questions of the origins and expression of human needs and motives.
David McClelland is professor of psychology and chairman of the Department of Social Relations at Harvard University. His many research activities have been complemented by a willingness to participate in administrative and advisory capacities in such bodies as the Ford Foundation, the Fulbright Advisory Panel, the Social Science Research Council, and the National Institute of Mental Health. The extent of this participation, greater than for any of the other subjects, indicates a certain consciousness or acceptance of the social responsibilities of his theoretical life that is an important characteristic of his personality. I think it is clear that the motive is not, consciously, a desire for power. I think we will see that it is rather an outgrowth of certain personal, perhaps even religious traits. A more important example of this is the fact that during the current year (1963–64) he is attempting to apply his theory to the task of improving society, by attempting to actually stimulate the need for achievement in the populations of underdeveloped nations.
A Self-contained Stellar Vault Construction Method. The Vault of the Matthias Oratorio in the Inner City Parish Church of Budapest
Authors: Jobbik Eszter , Krähling János 
Published: January 2023

In the present study, we analysed the laser-scanned point cloud of the stellar vault of the Inner City Parish Church of Budapest's Matthias oratorio. Our analysis concerned the global geometry of the rib network, as well as the webbing. During the study of the rib system, we reconstructed a probable construction method of the late 15th – early 16th-century vault, which seems to be a self-contained construction system in regard to the rib system's plan, the height of the junction points and the curvature of the individual ribs. We found, that to the latter the widely known "Prinzipalbogen" theory applies, however, the "theory of the longest route", which is often mentioned together with the former, most likely was not used. Mapping the webbing and the ribs allowed us to examine the building technique of the webs too.
ReFocus: The Films of William Friedkin
Authors: Choe Steve 
Published: January 2023

This book is the first scholarly study of the films of William Friedkin. Friedkin is the director of genre-defining works such as The French Connection (1971) and The Exorcist (1973), controversial productions like Cruising (1980) and Killer Joe (2011), as well as understudied films including The Birthday Party (1968), Sorcerer (1977) and The Hunted (2003). It brings a comprehensive understanding to his creative oeuvre, closely analyzing this director’s films and television productions in relation to key theoretical issues around melodrama, the ideological boundaries between good and evil, the formations of modern institutions, problems of sovereignty, transgression, and the phenomenology of his obsessive imagery. Placing his work in the historical contexts of the Vietnam War and Nixon’s presidency, it also examines Friedkin’s representations of sex, violence, and crime after the dismantling of the Production Code and in light of the rise and fall of New Hollywood cinema. While considering the trajectory of Friedkin’s work both historically and theoretically, it refocuses this important American director’s output by considering all of his films as a body of work.
Feedback, Asynchronicity and Sonic Sociabilities: Arnaud des Pallières’s Adieu
Authors: Talijan Emilija 
Published: January 2023

This chapter addresses the way noise has been deployed within the sonic practice of French filmmaker Arnaud des Pallières in his film Adieu (2004). According to des Pallières, the politics of his filmmaking resides in the way his films reflect on experiences of which he has no lived experience. With Adieu, des Pallières considers the experience of migration purposefully obliquely. I argue that des Pallières favours noise as a means of respecting radical strangeness and alterity in his exploration of migrant experience because noise allows him to avoid the violence of identitarian politics. Adieu registers passing presences and absences through noise and asynchronicity, sharpening our responses in a necessary vulnerability that might itself be receptive to the traumatic nature of migration as an experience. This rigorous approach to the sonic opens up avisual dimensions in Adieu that not only evoke socially invisible presences, but simultaneously register them against the ground of historical echoes of past abuses.
Efficacy of lyophilised bacteria-rich faecal sediment and supernatant with reduced bacterial count for treating patients with Clostridioides difficile Infection – A novel method for capsule faecal microbiota transfer
Authors: Varga Adorján , Makszin Lilla , Bufa Anita , Sipos Dávid , Kása Péter , Pál Szilárd , Rosenstiel Philip , Sommer Felix , Kocsis Béla , Péterfi Zoltán 
Published: January 2023

Background and aimsFaecal microbiota transfer (FMT) has managed to earn its place in the Clostridioides difficile infection (CDI) guidelines by having comparable efficacy and recurrence rate of fidaxomicin. After more than 100 successful FMT administration through nasogastric tube, we started using hard gelatine capsules filled with lyophilised faecal sediment and supernatant. Our main question was whether uncoated capsules (containing faecal sediment or supernatant) are comparable to the widely used nasogastric tubes in CDI. We also investigated the effect of storage and time on the survival rate of bacteria in the samples.MethodsWe compared the efficacy of our capsules to other treatment options of CDI at the Department of Infectology at the University of Pécs (Hungary). For our study, stool was collected from a single donor. We treated 10 patients with relapsing CDI, 5 of them received supernatant, 5 received sediment. Donor samples were stored on 4 different temperatures and tested to determine the survival rates of bacteria. As pilot projects, we also assessed the changes of bacterial taxa, protein- and lipid compositions. Moreover, we selected 4 patients to compare their samples prior and after FMT by using microbiome (16S amplicon sequencing), protein, and lipid analyses.Results4 out of the 5 patients who received supernatant became symptomless within 2 days after FMT. In the sediment group 3 out of 5 patients were cured from CDI. Comparing the supernatant to the sediment, we found significantly lower number of colony-forming units in the supernatant. We found that -80°C is the most suitable temperature to store the samples. The stool lipid profiles of recipients showed a more diverse composition after FMT, and changes in the stool protein profiles were observed as well. In the microbiome analysis, we observed an increase in the alpha diversity after FMT.ConclusionsOur study of 10 patients showed good efficacy of lyophilised faecal supernatant using capsules. The single donor approach proved to be effective in our investigation. A significantly lower CFU number was sufficient for the effect, the separation can be achieved by widely available instruments. For storage temperature, -20°C was sufficient in our clinical practice.
Anemia is a risk factor for rapid eGFR decline in type 2 diabetes
Authors: Xie Lijie , Shao Xiaoqing , Yu Yifei , Gong Wei , Sun Fei , Wang Meng , Yang Yeping , Liu Wenjuan , Huang Xinmei , Wu Xia , Wu Huihui , Li Yiming , Zhang Zhaoyun , Wen Jie , He Min 
Published: January 2023

ObjectiveTo investigate the association between anemia and progression of diabetic kidney disease (DKD) in type 2 diabetes.MethodsThis was a retrospective study. A total of 2570 in-patients with type 2 diabetes hospitalized in Jinan branch of Huashan hospital from January 2013 to October 2017 were included, among whom 526 patients were hospitalized ≥ 2 times with a median follow-up period of 2.75 years. Annual rate of eGFR decline was calculated in patients with multiple admissions. A rate of eGFR decline exceeding -5 ml/min per 1.73 m2 per year was defined as rapid eGFR decline. The prevalence of DKD and clinical characteristics were compared between anemia and non-anemia patients. Correlation analysis was conducted between anemia and clinical parameters. Comparison of clinical features were carried out between rapid eGFR decline and slow eGFR decline groups. The risk factors for rapid DKD progression were analyzed using logistic regression analysis.ResultsThe prevalence of anemia was 28.2% among the 2570 diabetic patients, while in patients with DKD, the incidence of anemia was 37.8%. Patients with anemia had greater prevalence of DKD, higher levels of urinary albumin-to-creatinine ratio (UACR), serum creatinine, BUN, urine α1-MG, urine β2-MG, urine NAG/Cr, hsCRP, Cystatin C, homocysteine and lower eGFR, as compared to the patients without anemia. Anemia was correlated with age, UACR, eGFR, urinary NAG/Cr, hsCRP and diabetic retinopathy (DR). Logistic regression analysis of 526 patients with type 2 diabetes during the follow-up period showed that anemia was an independent risk factor for rapid eGFR decline.ConclusionAnemia is associated with worse renal function and is an independent risk factor for rapid eGFR decline in type 2 diabetes.