bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence and abundance of coral disease in Aceh Besar regency Aceh, Indonesia
Authors: Ulfah Maria , Turnip Iqbal Nindo , Octavina Chitra , Dewiyanti Irma , Purnawan Syahrul 
Published: January 2023

The aims of this research was to knew the prevalence, abundance and types of coral diseases detected in Peukan Bada Aceh Besar Regency. Method used in this research was a 20x2m belt transect with 3 replicates. Results show that the prevalence value was between 27,94% – 58,25%. The value was quite higher if compared with other prevalence on some place in indonesia. Average value of coral disease abundance in this research was 0,23 ind/m2. There was 13 types of coral disease found during sampling, including Fish Bite, Drupella Predation, Acanthaster planci Predation, White Syndrome, Ulcerative White Spot, Focal Bleaching, Non-Focal Bleaching, Invertebrate Galls, Sponge Overgrowth, Cyanobacteria, Pigmentation Response, Sedimentation Damage, Algae Overgrowth. The most infected coral genus was Acropora with branching growth form.Keywords:AbundanceConditionCoral diseasePrevalence
Study on shipyard location and model development
Authors: Rizwan Thaib , Husaini Husaini , Husin Husni , Akhyar Akhyar 
Published: January 2023

The shipyard location and model highly influence shipyard industry development. This study aims to assess the location feasibility and determine the shipyard model suitable for shipyard industry development in Kutaraja Fishing Port. The study was conducted in Kutaraja Fishing Port. AHP method was used to determine the location and model, then analyzed using the Expert Choice v11 software. The data were collected using questionnaire interviews and further allocated the value using paired comparison scale table. The result shows that the shipyard industry is feasible to be developed in an area where land parameters adjacent to the waters have a maximum value of 37.3% compared with the five other parameters. The suitable shipyard model to be developed in Kutaraja Fishing Port is the slipway type with a value of 46.1%.Keywords:LocationModelShipyard
SurvivalPath:A R package for conducting personalized survival path mapping based on time-series survival data
Authors: Shen Lujun , Mo Jinqing , Yang Changsheng , Jiang Yiquan , Ke Liangru , Hou Dan , Yan Jingdong , Zhang Tao , Fan Weijun 
Published: January 2023

Summary
The survival path mapping approach has been proposed for dynamic prognostication of cancer patients using time-series survival data. The SurvivalPath R package was developed to facilitate building personalized survival path models. The package contains functions to convert time-series data into time-slices data by fixed interval based on time information of input medical records. After the pre-processing of data, under a user-defined parameters on covariates, significance level, minimum bifurcation sample size and number of time slices for analysis, survival paths can be computed using the main function, which can be visualized as a tree diagram, with important parameters annotated. The package also includes function for analyzing the connections between exposure/treatment and node transitions, and function for screening patient subgroup with specific features, which can be used for further exploration analysis. In this study, we demonstrate the application of this package in a large dataset of patients with hepatocellular carcinoma, which is embedded in the package. The SurvivalPath R package is freely available from CRAN, with source code and documentation hosted at https://github.com/zhangt369/SurvivalPath.
Anti-Trypanosoma cruzi antibody profiling in patients with Chagas disease treated with benznidazole assessed by genome phage display
Authors: Rodriguez Carnero Luis Antonio , Kuramoto Andréia , Campos de Oliveira Léa , Monteiro Jhonatas Sirino , Setubal João Carlos , Cunha-Neto Edécio , Cerdeira Sabino Ester , Giordano Ricardo José 
Published: January 2023

Background
There have been significant improvements in Chagas disease therapy and it is now widely accepted that most patients with chronic disease might benefit from therapy. However, there are challenges to monitor drug efficacy and cure for these patients, which are important impediments for current and future therapies. Trypanosoma cruzi-PCR is highly variable while IgG seroconversion takes decades yielding variable results depending on the antigen(s) used for the assay.

Methods and results
We used the genomic phage display (gPhage) platform to perform a pairwise comparison of antigens and epitopes recognized by twenty individual patients with chronic Chagas disease before and after treatment with benznidazole. In total, we mapped 54,473 T. cruzi epitopes recognized by IgG from individual patients (N = 20) before benznidazole treatment. After treatment, the number of epitopes recognized by all patients was significantly smaller (21,254), a reduction consistent with a decrease in anti-T. cruzi antibodies. Most of these epitopes represent distinct fragments from the same protein and could, therefore, be grouped into 80 clusters of antigens. After three years of treatment with benznidazole, we observed a 64% reduction in the number of clusters of antigens recognized by patients (59 clusters before versus 21 clusters after treatment). The most abundant antigenic clusters recognized by patients correspond to the surface antigen CA-2 (B13) followed by the microtubule associated antigen, which highlights the value of these epitopes in Chagas disease diagnosis. Most importantly, quantitative pairwise comparison of gPhage data allowed for the prediction of patient response to treatment based on PCR status.

Principal finding
Here, we compiled a list of antigens and epitopes preferentially recognized by Chagas disease patients before and after benznidazole treatment. Next, we observed that gPhage data correlated with patient PCR-status and could, therefore, predict patient response to treatment. Moreover, gPhage results suggest that overall, independent of PCR status, treatment led to a reduction in the presence of T. cruzi-specific antibody levels and the number of antigens and epitopes recognized by these patients.

Conclusion
The gPhage platform use of unbiased library of antigens, which is different from conventional serological assays that rely on predetermined antigens, is a contribution for the development of novel diagnostic tools for Chagas disease.
Using mobile audiometry (Wulira App) to assess noise induced hearing loss among industrial workers in Kampala, Uganda: A cross-sectional study
Authors: Batte Charles , Atukunda Immaculate , Semulimi Andrew Weil , Nakabuye Mariam , Bwambale Festo , Mumbere Joab , Twinamasiko Nelson , Mukunya David , Nyarubeli Israel Paul , Mukisa John 
Published: January 2023

Background
Occupational noise is a common cause of hearing loss in low-income countries. Unfortunately, screening for hearing loss is rarely done due to technical and logistical challenges associated with pure tone audiometry. Wulira app is a valid and potentially cost-effective alternative to pure tone audiometry in screening for occupational hearing loss. We aimed to determine the prevalence of occupational hearing loss among workers in a metal industry company in Kampala district.

Methodology
We recruited 354 participants conveniently from a steel and iron manufacturing industry in Kampala. All eligible participants answered a pretested and validated questionnaire and were assessed for noise induced hearing loss in a quiet office room approximately 500 meters from the heavy machinery area using the Wulira app. Descriptive statistics such as proportions were used to describe the study population while inferential statistics were used to determine associations.

Results
Of the 354 participants sampled, 333 (94.1%) were male, and the median age was 27, IQR (25–30). Regarding the risk factors of hearing loss, fourteen (3.9%) had history of smoking and more than half (65.5%) had worked in the industry for more than 2 years. The overall prevalence of hearing loss among industrial workers was 11.3% (40/354). 16.2% and 9% had mild hearing loss in the right and left ear respectively. Bilateral audiometric notch was present where fourteen (4%) of the participants had notch in their right ear while seven (2%) had notch in their left ear. Residing outside Kampala district was associated with hearing loss (OR, 95% CI, 0.213 (0.063–0.725), p = 0.013).

Conclusion
One in 10 workers in a metal manufacturing industry in Kampala had occupational hearing loss. Industrial workers residing outside Kampala were likely to develop hearing loss. Periodic screening should be done for early detection and intervention to prevent progression of hearing loss in this population.
Thoracic outlet syndrome (TROTS) registry: A study protocol for the primary upper extremity deep venous thrombosis section
Authors: Schropp Ludo , de Kleijn Robert J. C. M. F. , Westerink Jan , Nijkeuter Mathilde , Vonken Evert-Jan , van der Schaaf Irene C. , Goedee H. Stephan , Vrancken Alexander F. J. E. , van Hattum Eline S. , Petri Bart-Jeroen , de Borst Gert J. ,   TROTS registry collaborators
Published: January 2023

Introduction
There is a lack of comprehensive and uniform data on primary upper extremity deep venous thrombosis (pUEDVT). pUEDVT includes venous thoracic outlet syndrome related upper extremity deep venous thrombosis (UEDVT) and idiopathic UEDVT. Research on these conditions has been hampered by their rarity, lack of uniform diagnostic criteria, and heterogeneity in therapeutic strategies. To improve current research data collection using input of all various pUEDVT treating medical specialists, we initiated the ThoRacic OuTlet Syndrome (TROTS) registry. The aim of the TROTS registry is to a) collect extensive data on all pUEDVT patients through a predefined protocol, b) give insight in the long term outcome using patient reported outcome measures, c) create guidance in the diagnostic and clinical management of these conditions, and thereby d) help provide content for future research.

Methods and analysis
The TROTS registry was designed as an international prospective longitudinal observational registry for data collection on pUEDVT patients. All pUEDVT patients, regardless of treatment received, can be included in the registry after informed consent is obtained. All relevant data regarding the initial presentation, diagnostics, treatment, and follow-up will be collected prospectively in an electronic case report form. In addition, a survey containing general questions, a Health-related Quality of Life questionnaire (EQ-5D-5L), and Functional Disability questionnaire (Quick-DASH) will be sent periodically (at the time of inclusion, one and two years after inclusion, and every five years after inclusion) to the participant. The registry protocol was approved by the Medical Ethical Review Board and registered in the Netherlands Trial Register under Trial-ID NL9680. The data generated by the registry will be used for future research on pUEDVT and published in peer reviewed journals.

Conclusion
TROTS registry data will be used to further establish the optimal management of pUEDVT and lay the foundation for future research and guidelines.
Metabolomics of a neonatal cohort from the Alliance for Maternal and Newborn Health Improvement biorepository: Effect of preanalytical variables on reference intervals
Authors: Jafri Lena , Khan Aysha Habib , Ilyas Muhammad , Nisar Imran , Khalid Javairia , Majid Hafsa , Hotwani Aneeta , Jehan Fyezah 
Published: January 2023

Background
The study was conducted to determine reference interval (RI) and evaluate the effect of preanalytical variables on Dried blood spot (DBS)-amino acids, acylcarnitines and succinylacetone of neonates.

Methodology
DBS samples were collected within 48–72 hours of life. Samples were analyzed for biochemical markers on tandem mass spectrometer at the University of Iowa. Comparison of RI across various categorical variables were performed.

Results
A total of 610 reference samples were selected based on exclusion criteria; 53.2% being females. Mean gestational age (GA) of mothers at the time of delivery was 38.7±1.6 weeks; 24.5% neonates were of low birth weight and 14.3% were preterm. Out of the total 610 neonates, 23.1% were small for GA. Reference intervals were generated for eleven amino acids, thirty-two acylcarnitines and succinylacetone concentrations. Markers were evaluated with respect to the influence of gender, GA, weight and time of sampling and statistically significant minimal differences were observed for some biomarkers.

Conclusion
RI for amino acids, succinylacetone and acylcarnitine on DBS has been established for healthy neonates, which could be of use in the clinical practice. Clinically significant effect of GA, weight, gender and time of sampling on these markers were not identified.
Structural and spectroscopic properties of voriconazole and fluconazole – Experimental and theoretical studies
Authors: Drabińska Beata , Dettlaff Katarzyna , Kossakowski Kacper , Ratajczak Tomasz , Kujawski Radosław , Mikołajczyk Agnieszka , Kujawski Jacek 
Published: January 2023

Abstract
The article compares the experimental Fourier transform-infrared, Ultraviolet-visible (UV-vis), and proton nuclear magnetic resonance (1H NMR) spectra of voriconazole and fluconazole with the density functional theory (DFT) calculations using five different functionals. The results were compared with previously reported data related to its analogue – posaconazole. The analysis of calculated infrared (IR) spectra with the use of PBE1PBE (voriconazole) or APF (fluconazole) functionals shows good accordance with the experimental IR spectrum. The best compatibility between the experimental and theoretical UV spectra was observed with the use of PBE1PBE or B3LYP functionals for voriconazole or fluconazole, respectively. The reason for the difference in the UV-vis spectra of voriconazole and fluconazole was discussed based on linear response time-dependent DFT and natural bond orbital methods. The calculated 1H NMR spectrum shows that the DFT formalism, particularly the M06L or B3LYP functionals, gives an accurate description of the voriconazole and fluconazole chemical shifts.
New plant resistance inducers based on polyamines
Authors: Czerwoniec Patrycja 
Published: January 2023

Abstract
The novel and revolutionary approach to plant protection presented in this work, based on the preparation of bifunctional salts of a plant resistance inducer combined with a polyamine cation, may become a potential solution in the future for reducing the effects of abiotic and biotic stresses to which the plant is exposed. This study presents the synthesis, physical properties, phytotoxicity, and systemic acquired resistance (SAR) induction efficacy of new salts composed of the anion of plant resistance inducers and N,N,N,N′,N′,N′-hexamethylpropane-1,3-diammonium cation (5 salts), N,N,N,N′,N′,N′-hexamethyl-butane-1,4-diammonium cation (5 salts), spermidine salicylate, and spermine salicylate. SAR induction efficiency tests were performed on tobacco, Nicotiana tabacum var. Xanthi, infected with the tobacco mosaic virus.
Comparison of the corrosion resistances of chromium-passivated and cerium-passivated Zn/NdFeB magnets
Authors: Zhang Pengjie , Chen Jing , Yang Hongyi , Xu Guangqing , Lv Jun , Cui Jiewu , Sun Wei , Li Bingshan , Wang Dongmei , Wu Yucheng 
Published: January 2023

Abstract
Chromium-free passivation of Zn coating on NdFeB magnets becomes a research hotspot due to the serious harm of chromium ions to the human body. Chromium-based and cerium-based passivation technologies are conducted on electroplating Zn/NdFeB respectively. Morphologies, elemental compositions and phase structures of the two passivated coatings are characterized by scanning electron microscopy, X-ray diffraction and X-ray photoelectron spectroscopy, respectively. The corrosion resistances of the two passivated specimens are compared by neutral salt spray test, accelerated aging test and electrochemical measurements. A complete and smooth passivation film can be obtained on the surface of Zn/NdFeB, filling the gaps and pores in Zn coating. Compared with un-passivated Zn/NdFeB, Zn(Ce)/NdFeB and Zn(Cr)/NdFeB possess excellent corrosion resistance. In comparison, Zn(Ce)/NdFeB possesses excellent anti-corrosion performance, increasing the red-rust appearing time from 288 to 432 h, which is still lower than that of Zn(Cr)/NdFeB (528 h). Therefore, the self-repair effect of cerium passivation technology during the corrosion process should be further studied to achieve the purpose of replacing chromium passivation technology.
Study the effect of adding zirconia particles to nickel–phosphorus electroless coatings as product innovation on stainless steel substrate
Authors: Abed Khalid Mutashar , Radhi Nabaa S. , Jasim Ahlam Hamid , Al-Khafaji Zainab S. , Radhi Sabaa , Hussien Safa A. 
Published: January 2023

Abstract
Scholars have spent much time studying metal deposition procedures involving the deposition of electroless nickel, alloy, and composite coatings on various surfaces; the most current uses were feasible advantages of the coatings’ many good properties for achieving the final product innovation. Lately, these coatings have demonstrated intriguing wear and corrosion resistance features, resulting in several innovative macro-level developments. The notion of composite coating by co-deposition coating has been presented in this article. The characteristics of Ni–Pb alloy coatings were examined by inserting

ZrO

2

{{\rm{ZrO}}}_{2}

particles into the electroless deposited solution. The stainless steel (SS) specimens have been electroless coated with Ni–Pb and

ZrO

2

{{\rm{ZrO}}}_{2}

nanoparticles (size = 30–70 nm) at 0, 10, and 20 g/L amounts. The materials have been examined using scanning electron microscope and atomic force microscope, followed by wear-resistant and microhardness testing. According to the investigation findings, including inert particles improved the hardness magnitude and wearing resistance considerably. The base metal exhibited the highest wear rate at 10 N, while the wear rate decreased in the Ni–Pb–

ZrO

2

{{\rm{ZrO}}}_{2}

-coated SS316L by 34%. The Vickers hardness magnitudes of the Ni–Pb–

ZrO

2

{{\rm{ZrO}}}_{2}

-coated samples at different

ZrO

2

{{\rm{ZrO}}}_{2}

contents (0, 10, and 20 g/L) were 19, 50, and 81%, respectively.
Chitosan nanocomposite film incorporating Nigella sativa oil, Azadirachta indica leaves’ extract, and silver nanoparticles
Authors: Batubara Afnan S. , Obaid Najla A. , Alharbi Hanan M. , Altalhi Turki Mohammed , Alasmari Mohammed Abdullah , Alghamdi Ammar Zuhair , Sharmin Eram 
Published: January 2023

Abstract
Nanocomposite films have been prepared from chitosan, cinnamaldehyde, Nigella sativa or blackseed oil, and silver nanoparticles (NPs) biosynthesized in Azadirachta indica or neem leaves’ extract. The methodology involved simple blending of components through “green chemistry” route. The films obtained were soft and foldable. The morphology by scanning electron microscopy confirmed the inclusion of NPs in the films. Microbial penetration study demonstrated that the films offered good resistance to secondary bacterial infection. The antibacterial study against Staphylococcus aureus (ATCC 29213) and E. coli (ATCC 25922) indicated moderate antibacterial behavior of the films. The swelling behavior in water, phosphate buffer saline, and simulated wound fluid was found to be appropriate for use as wound dressings. The films were biodegradable in soil and showed good thermal stability up to 200°C.
Thermal and mechanical properties of poly(lactic acid)/poly(butylene adipate-co-terephthalate)/calcium carbonate composite with single continuous morphology
Authors: Song Qinghuan 
Published: January 2023

Abstract
Poly(lactic acid)/poly(butylene adipate-co-terephthalate) with a content ratio of 90/10, and its calcium carbonate (CaCO3) composites with nano- and micro-sized particles were prepared by melt mixing. The dependence of thermal and mechanical properties of the composites on the particle size and addition content of the CaCO3 filler was investigated. The composite containing five parts micro-sized filler (abbreviated as 90L10B5mC, similarly hereinafter) exhibited α and α′ crystallines on cooling as 90L10B without fillers. 90L10B11mC and 90L10B11n5mC exhibited only α′ crystalline, and the others exhibited no discernible crystalline. Jeziorny method showed that the crystallization mode of poly(lactic acid) chains in different composites was close, and Mo method showed that the crystal growth mode in 90L10B11n5mC was different from others. Changes in thermal and mechanical properties were attributed to the overall connection strength which was dependent on the particle size and addition content of the CaCO3 filler. From the perspective of industrialization, 90L10B5n11mC was preferred.
Rapid and efficient microwave-assisted extraction ofCaesalpinia sappanLinn. heartwood and subsequent synthesis of gold nanoparticles
Authors: Thanayutsiri Thana , Patrojanasophon Prasopchai , Opanasopit Praneet , Ngawhirunpat Tanasait , Laiwattanapaisal Wanida , Rojanarata Theerasak 
Published: January 2023

AbstractSince microwave (MW)-assisted synthesis of gold nanoparticles (AuNPs) usingCaesalpinia sappan(CS) extract as both a reducing and stabilizing agent is currently unavailable, a MW-based synthesis protocol was investigated and presented for the first time in this work. In addition, to rapidly prepare the reactant for this purpose, the MW-assisted extraction of CS heartwood was studied. From the optimization experiments, it was found that the extraction using the MW irradiation at 300 W for 3 min produced the extract with high and reproducible brazilin content which could be readily used for the synthesis of AuNPs. Under the optimal synthesis conditions, roughly spherical CS-AuNPs with an average diameter size of 49.6 nm and acceptable 28-day stability were obtained within only 1 min. The resulting CS-AuNPs were capable of selective binding to Fe2+, Fe3+, and Al3+, leading to particle aggregation as well as noticeable change of color and shift of UV-Vis absorption maxima. From these results, CS-AuNPs could be fabricated via this fast, green, and efficient route. Furthermore, their potential application for colorimetric sensing of certain metal ions was preliminarily explored and proposed in this work.
Removal efficiency of dibenzofuran using CuZn-zeolitic imidazole frameworks as a catalyst and adsorbent
Authors: Nguyen Thanh Q. C. , Tran Huy B. , Nguyen Nghia K. , Nguyen Nhut M. , Dang Giao H. 
Published: January 2023

Abstract
Dioxins/furans are classified as highly toxic chemicals that seriously affect human health. To remove dioxin residues from contaminated water, CuZn-ZIFs, a material from bimetallic zeolitic imidazolate frameworks (ZIFs) has been synthesized and explored its efficacy treatment with dibenzofuran (DBF). The pristine structure of CuZn-ZIFs was confirmed using powder X-ray diffraction, Fourier-transform infrared, thermogravimetric analysis, energy-dispersive X-ray, Brunauer–Emmett–Teller, and scanning electron microscopy. CuZn-ZIFs exhibited its role as a heterogeneous catalyst promoting H2O2 oxidation and as an adsorbent in DBF treatment. Herein, at room temperature, more than 86% of DBF adsorbed and 90% of DBF degraded in the presence of H2O2 with 10 mg catalyst dosage, 30 ppm of DBF within 40 and 60 min, respectively. Remarkably, the CuZn-ZIFs’ reusability of each process showed a high efficacy removal with over 80% after five cycles. Therefore, CuZn-ZIFs synthesized could be a prospective candidate for the indirect or direct degradation of dioxins/DBF derivatives from contaminated water.