bluuebunny/crossref_metadata_2025_split huggingface dataset:
The mission of the psychopedagogue
Authors: Tavares Reis Gilmar 
Published: August 2023

The genetic content of a person determines his characteristics and his process of evolution. However, in addition to the hereditary factor, it is verified that there is influence of the cultural environment and the level of harmonious integration of the child with the world in its surroundings on the development of the same, which is the object of study of Psychopedagogy. It is a discipline of the Human Sciences, whose beginning took place in the nineteenth century, with the demographic expansion of the post-war period, but its importance is extremely high for the present day, in which there is the search for a better orientation of knowledge and a deeper maturation of human learning. Psychopedagogy is a systematic study, closely linked to psychoanalysis and medicine, on the conditioning factors of behavior and lifestyle and their influence on human development in its most varied aspects, from cognitive functions to social interactions. The work of the psychopedagogue is to contribute to the optimized school formation of students through methods developed for each specific case. Through the interventions of the psychopedagogue in the educational process, it is possible to reverse learning deficits, help the inclusion of children with special needs and improve the social integration of the student in the environment in which he is inserted. The objective of the bibliographic research is to analyze the true contributions of psychopedagogy to education and to enumerate the main challenges experienced by the professional in the school institution. The bibliographies used are scientific and review articles, monographs and dissertations that report the performance of the psychopedagogue in the educational field. In this way, the work emphasizes the mission of the psychopedagogue, which is to contribute so that all individuals can assimilate contents and learn efficiently and effectively, promoting means of obtaining a healthier and more complete environment. human development, in addition to affirming the constant need for this professional in the educational environment.
Ból głowy z nadużywania leków przeciwbólowych – przegląd aktualnej literatury
Authors: Grużewska-Piotrowska Kinga , Grużewska Agnieszka 
Published: August 2023

Wprowadzenie: Wiele osób stosuje leki przeciwbólowe szczególnie w celu zatrzymania bólu głowy, nie zdając sobie sprawy, że niewłaściwe stosowanie tych substancji może wywoływać ten ból. Chorzy często stosują leki OTC i nie traktują tych środków jako potencjalnie niebezpiecznych. Schemat, w którym osoba z bólem przyjmuje coraz więcej leków, które wywołują ból może prowadzić do uzależnienia. W polskim piśmiennictwie można się spotkać z określeniami m.in.: „ból głowy z odbicia”, „polekowy ból głowy” „ból głowy indukowany lekami”. W obowiązującej Międzynarodowej Klasyfikacji Bólów Głowy 3 beta stosuje się określenie ‘medication overuse headache’ (MOH), co można przetłumaczyć jako „ból głowy z nadużywania leków”. Nazwa ta sugeruje występowanie bólów głowy w konsekwencji nadużycia dowolnych preparatów medycznych, ale według klasyfikacji wiąże się ona wyłącznie z nadużyciem leku lub leków stosowanych w doraźnej terapii przeciwbólowej.
Cel pracy: Celem tego przeglądu jest zebranie i podsumowanie aktualnej wiedzy na temat etiologii, epidemiologii i sposobach leczenia w bólu głowy spowodowanym nadużywaniem leków.
Materiały i metody: Ten przegląd systemowy oparto na dostępnych danych zgromadzonych w bazie PubMed oraz wyszukiwarce internetowej Google Scholar przy użyciu następujących wyrażeń: „ból głowy spowodowany nadużywaniem leków przeciwbólowych”, „główne czynniki ryzyka MOH”, „patofizjologia polekowych bólów głowy”, „leczenie bólu głowy spowodowanego nadużywaniem leków”
Wnioski: Ból głowy z nadużywania leków przeciwbólowych jest problemem ogólnoświatowym. Istnieje wiele czynników ryzyka odpowiedzialnych za rozwój tej choroby. Niektóre z nich są modyfikowalne, więc należy się na nich skupiać i edukować pacjentów i ich rodziny na temat tolerancji dawek przyjmowanych leków oraz możliwych uzależnieniach. Potrzebne są szeroko zakrojone randomizowane badania kliniczne, które pozwoliłyby porównać różne schematy leczenia i określić najlepsze podejście oparte na dowodach. Do tego czasu należy się skupiać na zwiększeniu świadomości o bólach głowy z nadużywania leków w populacji ogólnej. Leczenie MOH wymaga indywidualnego podejścia do pacjenta. Po zakończeniu leczenia ważne są regularne kontrole, by zapobiec nawrotom choroby.
Overview of cyclodextrins and medicinal products containing cyclodextrins currently registered in Poland
Authors: Napiórkowska Ewa 
Published: August 2023

Cyklodekstryny należą do cyklicznych oligosacharydów o unikalnych zdolnościach do tworzenia niekowalencyjnych kompleksów inkluzyjnych typu gospodarz-gość z wieloma cząsteczkami o właściwościach hydrofobowych, w tym także lekami. W efekcie mogą poprawiać rozpuszczalność wiązanych cząsteczek, a także zwiększać ich stabilność. Liczne zastosowania cyklodekstryn, m.in. w produkcji żywności, przemyśle kosmetycznym oraz naukach farmaceutycznych, świadczą o ich uniwersalności. Przeanalizowanie potencjału cyklodekstryn w naukach farmaceutycznych stwarza nowe możliwości poprawy właściwości fizykochemicznych leków, tworzenia nowych formulacji, projektowania systemów dostarczania leków, a także rozwoju innowacyjnych metod leczenia. Celem pracy było zebranie najważniejszych aspektów dotyczących cyklodekstryn, w tym ich budowy, sposobu tworzenia kompleksów inkluzyjnych, zastosowania w przemyśle farmaceutycznym, a także bezpieczeństwa stosowania cyklodekstryn. Artykuł obejmuje także przegląd dostępnych produktów leczniczych zarejestrowanych w Polsce zawierających w swoim składzie cyklodekstryny, wraz ze wskazaniami do ich stosowania oraz podaniem postaci farmaceutycznych. Różnorodność dostępnych produktów leczniczych podkreśla potencjał wykorzystania cyklodekstryn w projektowaniu nowych leków.
THE EFFECT OF PERCEPTIONS OF EASE OF USE AND USEFULNESS ON IMPLEMENTATION OF SAK EMKM IN SMALL AND MEDIUM ENTERPRISES (UKM) IN POLEWALI
Authors: Wahyuni Sry 
Published: August 2023

ABSTRACT

Purpose – The purpose of this study was to examine (1) the effect of perceived of Ease of Use, and (2) the effect of perceived usefulness on the implementation of SAK EMKM in Polewali.
Design/methodology/approach – The theory used in this research is the Technology Accepted Model (TAM).
Findings – The results of this study indicate: (1) perceived ease of use has a positive and significant effect on the implementation of SAK EMKM and (2) perceived usefulness has a positive and significant effect on the implementation of SAK EMKM.
Originality – The population in this study were 132 small and medium enterprises in the city of Polewali
Keywords: Technology Accepted Model (TAM), Perception of Ease of Use, Perception usefulness, Implementation of SAK EMKM
Paper Type Research Result
Blow-up criteria and instability of standing waves for the inhomogeneous fractional Schrodinger equation
Authors: Feng Binhua , He Zhiqian , Liu Jiayin 
Published: August 2023

In this article, we study the blow-up and instability of standing waves for theinhomogeneous fractional Schrodinger equation $$ i\partial_tu-(-\Delta)^su+ |x|^{-b}|u|^{p}u=0, $$ where \(s\in (\frac{1}{2},1)\), \(0<b<\min \{2s,N\}\) and \(0<p< \frac{4s-2b}{N-2s}\). In the \(L^2\)-critical and \(L^2\)-supercritical cases, i.e.,\(\frac{4s-2b}{N}\leq p< \frac{4s-2b}{N-2s}\), we establish general blow-up criteriafor non-radial solutions by using localized virial estimates. Based on theseblow-up criteria, we prove the strong instability of standing waves. For more information see https://ejde.math.txstate.edu/Volumes/2021/39/abstr.html
Pemahaman Teologis Yang Benar Tentang Perjamuan Kudus
Authors: Widodo Agus , Tedja Mahananie Esa 
Published: August 2023

Holy communion as one of the important doctrine as part of the curch. The doctrine is real to a believer in their connection with the church. A theologian named C.J Den Heyer stated, ““holy communion must be based on Bible and tradition” in the meantime, while Jesus together with His disciples held a holy communion by eat bread and drink wine (Mrk 14:22-25, Mat 26:26-29, Luk 22-14-20) as a mandate for holy communion at feast night’s holy communion, also written in the epistle of Paul to Chorintian (1Chorintian 10;14-22 and 11:17-34) about ‘holy communionn’ as a stong reason for the church of God to give a meaning based on true understanding of holy communion. The congregation must have a tru understanding about holy communion. To reach a true understanding about holy communion it must be based on the teological background of the Bible. Holy communion is the mandate from God Himself through His discipkes all aroud the world, “do in rememberence of Me.” Holy communion as an action to remembering the work of a mighty savior at the cross to redeem sins of man and stated the faith to Him.
Abstrak Indonesia
Perjamuan kudus adalah salah satu bagian penting yang diajarkan dalam doktrin gereja. Doktrin gereja ini sangat riil bagi orang percaya dalam hubungannya dengan gereja. Seorang teolog bernama C.J Den Heyer mengatakan bahwa, “Perjamuan kudus berangkat dari dasar Firman Tuhan dan tradisi.”3 Pada waktu Yesus bersama-sama dengan murid[1]murid-Nya mengadakan perjamuan kudus makan roti dan minum anggur (Mrk 14:22-25, Mat 26:26-29, Luk 22-14-20) sebagai amanat penetapan perjamuan malam, juga surat Paulus untuk jemaat di Korintus (1Korintus 10;14-22 dan 11:17-34) tentang ‘Perjamuan Tuhan’ sebagai alasan kuat bagi gereja Tuhan untuk memberikan makna berdasarkan pemahaman yang benar tentang perjamuan kudus. Umat Tuhan dalam gereja harus memiliki pemahaman yang benar tentang perjamuan kudus. Untuk mencapai pemahaman yang benar tentang perjamuan kudus harus berdasarkan kepada dasar teologis dari kebenaran Alkitab. Perjamuan kudus adalah perintah langsung dari Tuhan untuk jemaat-Nya secara universal, “perbuatlah ini menjadi peringatan akan daku.” Perjamuan kudus sebagai tindakan mengingat karya Juruselamat di kayu salib menebus dosa-dosa manusia dan meneguhkan keyakinan iman kepada-Nya.
Analisis Peran Pendidikan Kewarganegaraan Dalam Membangun Sikap Nasionalisme Warga Negara
Authors: Salsabila Imelda Saskia  
Published: August 2023

Karakteristik Nasionalisme yang melambangkan kekuatan suatu Negara dan asprasi yang berkelanjutan, kemakmuran, pemeliharaan rasa hormat dan penghargaan untuk hukum. Namun akhir-akhir ini nasionalisme warga Indonesia semakin menurun. Hal ini seiring dengan permasalahan yang dihadapi bangsa Indonesia. Berbagai masalah yang dihadapi oleh Bangsa Indonesia mulai dari masalah kemiskinan, pengangguran, terorisme dan lain sebagainya. Metode penelitian yang digunakan dalam penelitian ini menggunakan pendekatan kualitatif dengan penelitian deskriptif berdasarkan studi kasus dan telaah pustaka yang bertujuan untuk mengalisis peran pendidikan kewarganegaraan dalam membangun sikap nasionalisme warga negara. Hasil penelitian ini menunjukan, bahwa pendidikan kewarganegaraan erat kaitannya dengan nilai-nilai nasionalisme dan patriotisme. Hal tersebut bukanlah mitos, karena memang secara substantif pendidikan kewarganegaraan bertujuan untuk membentuk warga negara yang baik. Pendidikan Kewarganegaraan dimaksudkan untuk membentuk peserta didik menjadi manusia yang memiliki rasa kebangsaan dan cinta tanah air. Tujuan pendidikan kewarganegaraan adalah untuk menciptakan warga Negara yang memiliki wawasan mengenai kenegaraan, menanamkan rasa cinta tanah air, dan merasa bangga sebagai warga Negara Indonesia. Untuk membangun nasionalisme generasi muda sebagai wujud pendidikan kewarganegaraan adalah ungkapan perasaan senasib sepenanggungan dalam lingkup bangsa dalam bentuk kepedulian dan kepekaan akan masalah-masalah yang dihadapi bangsa, termasuk di dalamnya masalah yang berkaitan dengan rasa solidaritas sebangsa dan setanah air.
The criminal hierarchy in Russia: features and characteristics.
Authors: Novozhilov Sergei Sergeevich 
Published: August 2023

The article highlights the main problems associated with the definition of the criminal hierarchy of Russia, its criminological features and characteristics. The criminal hierarchy represents a system of relations that have developed in the criminal environment and determine the order of subordination of the lower links to the higher ones. The author conducts a comparative analysis of the criminal hierarchy of Russia and the hierarchy operating in places of deprivation of liberty (penitentiary hierarchy), noting that the criminal hierarchy is a broader concept and includes the prison (penitentiary) hierarchy, which is its integral part. The author presents various opinions of scientists on this issue concerning the functioning, characteristics and features of the criminal hierarchy of Russia. The main conclusion of the study is that there is not and cannot be a single criminal hierarchy on the territory of Russia with a single control center, a strict system of subordination and subordination of the lower levels of criminal communities (organizations) to the higher ones. The analysis of the operational situation shows that various OPS and EOPGS operate in the Russian Federation, including those headed by persons with leadership status who carry out their activities within the so-called "thieves' community", which is the most structured segment of the criminal hierarchy, in addition, prison (penitentiary hierarchy) operates in correctional institutions, which is also a segment of the criminal hierarchy. Only the totality of all segments forms the so-called criminal hierarchy of Russia (the criminal world of Russia), which is not a single and integral structure, and the system of subordination is characteristic only for its individual elements.
To flea or not to flea: survey of UK companion animal ectoparasiticide usage and activities affecting pathways to the environment
Authors: Perkins Rosemary , Goulson Dave 
Published: August 2023

Due to the convenience and efficacy of modern ectoparasiticides, routine prophylactic use has become commonplace for dogs and cats. However, the environmental consequences of this large-scale use are not well-understood, and multiple potential pathways for ectoparasiticides to the environment exist. Of particular concern is the potential for topically applied ectoparasiticides to pass to waterways, both down-the-drain via wastewater treatment plants and directly through swimming. In this online cross-sectional survey of 1,009 UK cat and dog owners, we investigated ectoparasiticide usage and the frequency of activities that are likely to result in transfer of the active substance to the environment, with a focus on pathways to waterways. A total of 603 dog owners and 406 cat owners completed the survey. Amongst dog and cat owners, 86.1% and 91.1% had administered an ectoparasiticide treatment to their pet in the preceding 12 months. Imidacloprid was the most frequently administered ectoparasiticide in both cats and dogs, followed by fluralaner in dogs and fipronil in cats. Eighty-four percent of owners who applied topical ectoparasiticides to their dog said they were aware of product warnings regarding swimming and bathing after application. Spot-on treated dogs were reported to swim significantly less frequently than non spot-on treated dogs (p = 0.007); however, 36.2% were reported to swim at least monthly. Similarly, significant differences were found in bathing frequency between spot-on treated and non spot-on treated dogs, with treated dogs less likely to be bathed at frequent (weekly) intervals, however 54.6% were reported to be bathed at least monthly. Washing of bedding was unaffected by ectoparasiticide treatment, and 87.8% of dog owners and 69.1% of cat-owners reported washing their pet’s bedding at least every 3 months, suggesting that residue washoff from bedding may be occurring for most topically treated animals. Results suggest that transfer of ectoparasiticides to the environment is likely to occur for many of the millions of animals treated annually in the UK, with imidacloprid spot-on treated dogs estimated to swim, be bathed and have their bedding washed over 3.3 million, 5 million and 6.3 million times per year, respectively.
Malignant Melanoma Metastasis to Bone Marrow: A Rare Case Report
Authors: Kumari Madhu , Sinha Sandhya Kumari , Bhadani Punam Prasad , Singh Avinash , Prasad Tanya 
Published: August 2023

Malignant melanoma is an aggressive neoplasm, its metastasis to bone marrow is rare phenomenon. Here, we are presenting a case of metastatic malignant melanoma to bone marrow with unknown primary in 40 years old patient along with review of literature. This case is diagnosed as metastatic malignant melanoma in bone marrow aspirate and biopsy specimen first. Diagnosis was done on the basis of classical histological features and with the help of immunohistochemistry. Radiological investigations were done to know primary site. Multiple metastasis in liver and vertebra were also identified. USG guided fine needle aspiration cytology of liver and biopsy of vertebral lesion were also performed, which confirms the diagnosis of malignant melanoma metastasis. In our case, patient died within one month after diagnosis. Early diagnosis of metastatic malignant melanoma will help clinicians to better understanding of course of disease, so they can provide best possible patient care and management. Clinicians must be aware of progression of disease, clinical manifestations of metastatic malignant melanoma.
Projected increases in extreme drought frequency and duration by 2040 affect specialist habitats and species in Scotland
Authors: Kirkpatrick Baird Fairlie , Spray Deborah , Hall Jeanette , Stubbs Partridge Julia 
Published: August 2023

Abstract

Climate‐driven increases in drought occurrence are an overlooked risk in temperate climates, which may be less resilient to water scarcity than arid habitats. Scotland provides an example of a temperate oceanic climate in which drought risk is understudied, but could have substantial ecological impacts, particularly in combination with additional stressors.

We modelled changes to risk of extreme drought occurrence in Scotland, and considered potential impacts of these changes on two key habitats, ombrotrophic (precipitation fed) wetlands and temperate rainforest. Using temperature and precipitation data from the UK Climate Projections 2018 and the drought index Standardized Precipitation‐Evapotranspiration Index, we calculated and mapped likely changes in extreme drought for the near future (2021–2040) in comparison to a baseline (1981–2001).

We found likelihood of extreme drought events increased from an average of one event every 20 years in the baseline period, to one event every 3 years by 2040. Typical events were projected to be up to 2–3 months longer, with an average of 11 extra drought months per decade. Increases were projected throughout the country, but the effect was most severe in the east, and during autumn.

Ombrotrophic wetlands have some level of adaptive resilience to drought, but are considered at high risk as several key sites are in drought hotspot areas. In contrast, Scotland's temperate rainforest is located in lower risk areas, but is typically less drought resilient. Potential impacts on these habitats include reductions in ecosystem services including carbon capture, reduced breeding success for multiple taxa and increased competition among plant communities, which threatens drought‐sensitive species.

These projections suggest that climate‐driven drought risk is a significant and imminent threat, even in wet climates. In Scotland, the results can direct mitigation and management actions to areas likely to be at greatest risk, as well as informing conservation interventions that can cope with drought. Additionally, other areas with a temperate oceanic climate may be at risk of extreme drought and could experience similar consequences. Therefore, these results have implications both for facilitating improved resilience to extreme drought in Scotland and for potentially overlooked impacts of drought in oceanic climates elsewhere.
Dopamine‐Based High‐Transparent Hydrogel as Bioadhesive for Sutureless Ocular Tissue Repair
Authors: Qian Yuna , Xu Kejia , Shen Liangliang , Dai Mali , Zhao Zelin , Zheng Yujing , Wang Haiou , Xie Hailin , Wu Xuan , Xiao Decheng , Zheng Qinxiang , Zhang Jinyi , Song Yang , Shen Jianliang , Chen Wei 
Published: August 2023

AbstractOcular injuries and their complications represent the most common causes of visual impairment. For ocular surgery, there is an unmet need for highly transparent bioadhesives with superior adhesion, biocompatibility, and regenerative properties. Herein, a novel high‐transparent bioadhesive hydrogel composed of gelatin methacryloyl (GelMA) and dopamine methacrylamide (DMA) is developed by in situ oxidative free‐radical polymerization. This bioadhesive hydrogel overcomes the fundamental weakness of mussel‐inspired adhesive copolymers in clinical practice by combining multiple favorable properties, including high light transmission, mechanical strength, adhesive strength, and biocompatibility. DMA significantly enhances corneal epithelial cells adhesion, proliferation, and migration on GelMA, and prevents the accumulation of reactive oxygen species (ROS) in corneal epithelial cells. In rabbit models of corneal and conjunctiva transplantation, the bioadhesive is able to decrease the inflammatory response and fibrosis formation induced by suture surgical trauma. In addition, the rabbit corneal stromal defect model reveals that the Gel/DMA bioadhesive could effectively seal corneal defects, accelerates corneal re‐epithelialization, and promotes wound healing. Thus, given the advantages of high bioactivity and simple preparation, the Gel/DMA bioadhesive represents a promising strategy for suture‐free ocular repair.
Solvent Exchange Induced In Situ Formed Hydrogel as Liquid Embolic Agents
Authors: Liu Menghui , Wang Yunzhi , Chen Yanlv , Li Liujun , Sun Yang , Li Yongchao , Yuan Yajun , Lu Pan , Zhang Wenkai , Pang Pengfei , Peng Xin , Shan Hong 
Published: August 2023

AbstractEndovascular embolization can selectively deploy embolic agents into diseased or injured blood vessels to complete the treatment. However, traditional embolic agents still face challenges, such as poor intravascular diffusivity, non‐biodegradable, unstable mechanical properties, radiolucency, and recanalization. Herein, we report a poly (lipoic acid‐tannic acid)/tromethamine/Galinstan (PLTTG) dimethyl sulfoxide (DMSO) solution‐derived hydrogel liquid embolic agent. By injecting PLTTG DMSO solution into body fluids, a PLTTG hydrogel can be formed in situ owing to the solvent exchange induced intra‐ and inter‐polymer hydrogen bonding and electrostatic interactions. Moreover, the gelation time and injection forces of the solution as well as the mechanical properties and embolic pressure of the obtained hydrogels can be adjusted by changing the concentration of PLTTG. The PLTTG hydrogel can effectively embolize the renal artery and femoral vein without recanalization and displacement in rabbit models. Furthermore, the hydrogel can embolize the ruptured femoral artery to arrest active bleeding. Owing to the advantages of the hydrogel, including adjustable gelation time, mechanical properties, viscosities, injection forces, and embolic pressure, as well as good biocompatibility and biodegradability, radiopacity, excellent embolization performance and intravascular diffusivity, easy usage, low cost, allowing it to be a potential embolic agent to treat multiple vascular diseases in clinic.