bluuebunny/crossref_metadata_2025_split huggingface dataset:
Towards the invasion of wild and rural forested areas in Gabon (Central Africa) by the Asian tiger mosquito Aedes albopictus: Potential risks from the one health perspective
Authors: Obame-Nkoghe Judicaël , Roiz David , Ngangue Marc-Flaubert , Costantini Carlo , Rahola Nil , Jiolle Davy , Lehmann David , Makaga Loïc , Ayala Diego , Kengne Pierre , Paupy Christophe 
Published: August 2023

Background
Since its first record in urban areas of Central-Africa in the 2000s, the invasive mosquito, Aedes albopictus, has spread throughout the region, including in remote villages in forested areas, causing outbreaks of Aedes-borne diseases, such as dengue and chikungunya. Such invasion might enhance Ae. albopictus interactions with wild animals in forest ecosystems and favor the spillover of zoonotic arboviruses to humans.
The aim of this study was to monitor Ae. albopictus spread in the wildlife reserve of La Lopé National Park (Gabon), and evaluate the magnitude of the rainforest ecosystem colonization.

Methodology
From 2014 to 2018, we used ovitraps, larval surveys, BG-Sentinel traps, and human landing catches along an anthropization gradient from La Lopé village to the natural forest in the Park.

Conclusions
We detected Ae. albopictus in gallery forest up to 15 km away from La Lopé village. However, Ae. albopictus was significantly more abundant at anthropogenic sites than in less anthropized areas. The number of eggs laid by Ae. albopictus decreased progressively with the distance from the forest fringe up to 200m inside the forest. Our results suggested that in forest ecosystems, high Ae. albopictus density is mainly observed at interfaces between anthropized and natural forested environments. Additionally, our data suggested that Ae. albopictus may act as a bridge vector of zoonotic pathogens between wild and anthropogenic compartments.
Determinants of non-adherence to home injury prevention practice among parents of under-five children in North Seberang Perai district, Penang: A mixed-methods study protocol
Authors: Rahim Nurul Iman Abdul , Kadir Shahar Hayati , Zulkefli Nor Afiah Mohd , Mohd Nazan Ahmad Iqmer Nashriq 
Published: August 2023

Background
Unintentional injury is a global burden that occurs everywhere, including in our homes. Young children are most vulnerable to home injuries because they still develop their physical and psychological skills and spend most of their time at home. Despite being largely preventable, three consecutive national surveys show no reduction in the rate of injury among children under five. More surprisingly, children from high-income families were found to have the highest incidence of injury, contradicting the findings from other countries.

Objective
This study aims to identify the determinants of non-adherence to unintentional home injury prevention practice among parents of under-five children in the North Seberang Perai district, Penang.

Methods
This sequential explanatory mixed-methods study consists of two phases consisting of a quantitative study which looks into respondents and their child’s sociodemographic status, their home injury prevention practice and the independent variables, followed by a qualitative study that interviews parents with non-adherence to home injury prevention practice and explore their barriers. In phase I, the parent or primary caregiver of a child age less than five years old who age 18 or older and is a Malaysian will be included in the study while being disabled or having a severe psychiatric disorder or having the index child diagnosed with chronic disease will make them not eligible to participate in the study. Derived using the two-group proportion formula, a sample size of 453 parents will be sampled among those with under-five children following up at the Maternal Child Health Department in the health clinics of North Seberang Perai using stratified systematic sampling. Chi-square/Fisher Exact test, simple logistic regression and multiple logistic regression will be used for data analysis. The sample will be stratified according to household income to look for associated factors and determinants of low prevention practice. In phase II, parents with a low score from the quantitative study will be selected to participate in the qualitative study using purposive sampling. A semi-structured interview using the help of an interview guide will be carried out and recorded with a voice recorder. The thematic analysis approach will be used to analyse the qualitative data.

Results
The study has been registered under the National Medical Research Registry.

Conclusion
It is hoped that findings from this study can shed light on the barriers faced by under-five parents in carrying out preventive measures at home.
Abordagem das Artes afro-brasileiras e africanas na BNCC: reflexões a partir da lei 10.639/03
Authors: Góes Washington Lopes 
Published: August 2023

Esse trabalho tem como objetivo fazer uma reflexão acerca da abordagem das Artes afro-brasileiras e africanas na Base Nacional Comum Curricular (BNCC) do Ensino Fundamental II à luz da Lei 10.639/03. Para tal, foi realizada uma pesquisa bibliográfica calcada no exame de artigos acadêmicos, livros, documentos, leis e normas oficiais que incidem nas formulações de políticas, planos e sistemas educativos. Foi possível chegar aos seguintes resultados: os estudos demonstraram que as abordagens referentes ao ensino da história e cultura africana e afro-brasileira no componente Artes quase nada estão contempladas na BNCC; problematizações acerca das questões estruturais e institucionais que são bases para uma cultura racista não estão presentes no documento. Palavras-chave: Lei 10.639/03 – Cultura Africana e Afro-brasileira – BNCC – Artes – Ensino Fundamental
Morphometry of the cold-climate Bory Stobrawskie Dune Field (SW Poland): Evidence for multi-phase Lateglacial aeolian activity within the European Sand Belt
Authors: Łopuch Michał , Zieliński Paweł , Jary Zdzisław 
Published: August 2023

Abstract
Aeolian dunes have been widely identified in the European Sand Belt, which was formed during the Pleniglacial and Late Glacial when cold and dry climatic conditions were favorable for intense Aeolian processes. In this study, we mapped and analyzed the fixed Bory Stobrawskie Dune Field (SW Poland) to determine factors that drive the evolution of dunes, expressed by the occurrence of different dune types and their spatial patterns. The study identified the longitudinal zonation within the dune field, as shown by the changeable proportion of specific dune types comparable to low-latitude dune fields. However, climatically controlled periodic and low sand supply combined with a changing vegetation cover caused the non-continuous and multi-phase evolution of the dune field. Additionally, we found that a dense pattern of streams has controlled the extent of the dune field. The trapping of sand by rivers led to a limitation of the dune field expansion; on the other hand, the supply of sand into rivers led to overloading of the fluvial system, affecting their transformation into braided rivers.
Intermittent vs. continuous swimming training on adipokines and pro-inflammatory cytokines in metabolic syndrome experimental model
Authors: Nayebifar Shila , Nakhaei Hossein , Kakhki Zohreh Borhani , Ghasemi Elham 
Published: August 2023

Abstract

Objectives
In this study, metabolic syndrome-affected rats were studied to examine how intermittent and continuous swimming training influenced adipokines and pro-inflammatory cytokines.

Methods
Forty-eight male Wistar rats were randomized in this experimental study into four groups (n=8), including normal control (NC), metabolic syndrome (MS), continuous swimming training with metabolic syndrome (CT-MS: load 0–3% body mass, 5 d/wk, for 8 weeks), and intermittent swimming training with metabolic syndrome (IT-MS: load 5–16% body mass, 5 d/wk, for 8 weeks). The serum levels of metrnl, adipolin, irisin, leptin, TNF-α, and IL-6 were measured using the ELISA test.

Results
The IT-MS and NC groups exhibited significantly lower leptin concentrations than the CT-MS group (p=0.001). The irisin, meteorin, and adipolin serum levels increased significantly in CT-MS and IT relative to the NC and CT-MS groups (p=0.001), with the changes being more pronounced in the IT group (p=0.05). TNF-α and IL-6 were inclined in the CT-MS group compared with the other three groups (p=0.001), while IL-6 was increased in the IT group (p=0.024).

Conclusions
Intermittent swimming is more effective than continuous swimming training in improving adipokines in rats with metabolic syndrome.
When Women’s Work Disappears: Marriage and Fertility Decisions in Peru
Authors: Mansour Hani , Medina Pamela , Velásquez Andrea 
Published: August 2023

Abstract
This paper studies the gendered labor market and demographic effects of trade liberalization in Peru. To identify these effects, we use variation in the exposure of local labor markets to import competition from China based on their baseline industrial composition. On average, the increase in Chinese imports during 1998–2008 led to a persistent decline in the employment share of low-educated female workers but had smaller and transitory effects on the employment of low-educated men. In contrast to the predictions of Becker’s model of household specialization, we find that the increase in import competition during this period increased the share of single low-educated people and decreased their marriage rates. There is little evidence that import competition affected fertility decisions. The results highlight the role of gains from joint consumption in marriage formation.
On Emergence, Again
Authors: Ferrari Francesco Maria , Bickhard Mark H. 
Published: August 2023

AbstractThe aim of the present paper is twofold. First, we are interested in assessing the validity of one version of Kim’s argument against genuine higher level causation. Second, we discuss Wilson’s proposal to consider a weaker notion of emergence as genuinely metaphysical and compatible with Non-Reductive Physicalism. Our conclusion is that both proposals fail: the first in preempting genuine (strong) emergent causation, whereas the second in ensuring a genuinely metaphysical status to weak emergence. After all, Wilson’s proposal strongly depends on the success of Kim’s, not only because it takes it as valid but, also, because in pursuing its own weaker model it shares the presuppositions that led Kim’s to failure. At the end of the day, Wilson’s conception of genuine weak emergence either breaks causal closure or is merely stipulative, namely confined at the descriptive level.
Nasal fluid sample as a reliable matrix for determination of cytokine levels in childhood asthma
Authors: Doulatpanah Mojtaba , Kocamanoğlu Meltem , Sözmen Eser Yıldırım , Öztürk Gökçen Kartal , Demir Esen , Gülen Figen , Akçay Yasemin 
Published: August 2023

Abstract

Objectives
Childhood asthma is a chronic disease with high incidence worldwide. As a lifelong disease, asthma has episodes. Inflammation continues to occur in the clinical remission of asthma. It can be difficult to diagnose childhood asthma, especially in clinical remission. We hypothesized that some cytokines secreted to nasal fluid from the airway during inflammation might help diagnose clinical remission of asthma. Moreover, sampling nasal fluid is an easy and non-invasive procedure, so it may be a preferable sampling method.

Methods
We measured levels of some interleukins (ILs), which are IL-4, IL-5, IL-6, IL-12p70, IL-13, IL-33, granulocyte-macrophage colony-stimulating factor (GM-CSF), periostin and thymic stromal lymphopoietin (TSLP) by Luminex magnetic bead-based immunoassay in nasal fluid and in serum of asthmatic children in clinical remission.

Results
We found that IL-5, IL-6, IL-33, and periostin had elevated levels in nasal fluid. IL-5 and IL-33 had increased levels in the nasal fluid of the patients with immunoglobulin E (IgE) high and low phenotypes. While the nasal fluid TSLP levels were positively correlated with most of the increased serum cytokine levels of non-allergic asthmatic children, the nasal fluid GM-CSF levels were positively correlated with most of the increased serum cytokine levels of the allergic asthmatic children.

Conclusions
IL-5, IL-6, IL-33, and periostin had elevated levels in the nasal fluid of the patients in clinical remission. The nasal fluid GM-CSF levels of the allergic patients and nasal fluid TSLP levels of the non-allergic patients had a positive correlation with most of the serum cytokine levels. Thus, our results showed that nasal fluid might be a preferable biological sample to diagnose asthma in children.
Presentation of new onset type 1 diabetes with diabetic ketoacidosis and hyperosmolar hyperglycaemia after a single dose of nivolumab and ipilimumab
Authors: Stathi Dimitra , Hussain Sufyan , Crawley Danielle , Karalliedde Janaka 
Published: August 2023

Summary
A Caucasian man in his 60s with recent diagnosis of metastatic renal cell carcinoma presented to the emergency department with a 5-day history of severe polyuria, polydipsia and fatigue and 1-day history of confusion, abdominal pain, nausea and vomiting. Investigations revealed an overlap of diabetic ketoacidosis (DKA) and hyperosmolar hyperglycaemic state (HHS). He had received the first dose of immunotherapy with nivolumab and ipilimumab 3 weeks prior to this attendance. New-onset type 1 diabetes (T1DM) was confirmed based on the clinical features at presentation, seropositivity for glutamic acid decarboxylase antibodies and significant insulin deficiency. He is currently on a multiple daily injections of insulin and uses intermittent-scanned glucose monitoring. Given the irreversible impact on beta-cell function and clinical response with insulin resulting in improved diabetes control, immunotherapy was resumed for his metastatic cancer with good radiological response. Although rare, new-onset T1DM can present with DKA and HSS overlap after a single dose of nivolumab/ipilimumab in individuals without pre-existing history of diabetes.

Learning points

Although rare, new onset of T1DM after immunotherapy can present with DKA and HSS overlap after a single dose of nivolumab/ipilimumab in individuals without pre-existing history of diabetes and normal glycaemic parameters.

Due to the irreversible destruction of beta-cells, treatment with steroids is not indicated in contrast to other settings such as immunotherapy-induced hypophysitis.

Presence of low c-peptide levels post-acute presentation is indicative of an irreversible impact on beta-cell function and supports resuming immunotherapy given the significant benefits on cancer prognosis.

Clinicians must maintain a high index of suspicion in regards to diagnosis and management of new-onset type 1 diabetes and advice patients on reporting symptoms suggestive of diabetes and/or diabetes-related hyperglycaemic emergencies.
Alternativas de manejo de la pudrición blanda del tomate mediante el uso de levaduras
Authors: García Murillo Paulo Germán 
Published: August 2023

En un estudio previo se determinó el alto potencial de control biológico de la levadura Pichia onychis cepa Lv027 contra Rhizopus stolonifer causante de la pudrición húmeda en tomate en la poscosecha. Por lo que el propósito de este trabajo fue establecer la concentración mínima efectiva de la cepa Lv027, determinar el tiempo óptimo de aplicación de la cepa Lv027, evaluar in vitro e in planta los efectos de la competencia por nutrientes y espacio de esta misma cepa contra R. stolonifer y observar la interacción de la cepa Lv027 en presencia de las esporangiosporas del mencionado fitopatógeno. En el primer ensayo, se seleccionó la concentración de 1x107células*ml-1 de la cepa Lv027, ya que presentó valores de antagonismo contra R. stolonifer de 86,2% a 6°C a 20°C de 85,1%. En el segundo, se estableció que al inocular la cepa Lv027 de la levadura mínimo 18 h antes que el fitopatógeno, se alcanza niveles de antagonismo del 88,0% a 6°C y del 100% a 20°C. En el tercero, se determinó el efecto de la cepa Lv027 sobre el crecimiento del micelio de R. stolonifer mediante la medición del peso seco, al ser ambos microorganismos cultivados al mismo tiempo en un medio sintético suplementado, con glucosa, fructosa y sacarosa, encontrándose una reducción de peso seco del micelio de R. stolonifer de 83,0%, 28,0% y 62,2% respectivamente; los anteriores resultados sugieren que la cepa Lv027 es más eficiente que R. stolonifer para la utilización de los mencionados azúcares como fuentes de carbono, reduciendo el crecimiento de este fitopatógeno. De otra parte, en las heridas hechas en frutos de tomate e inoculadas con la levadura antagonista y el fitopatógeno, se observa reducción en el desarrollo del tubo germinativo de las esporangiosporas de R. stolonifer a las 6 h de 19,0%, siendo éste muy inferior al producido por el fitopatógeno en ausencia de la cepa Lv027, en donde alcanza un valor promedio de 85,0%; a las 12 h, se observó la misma tendencia, pero con valores germinación de las esporangiosporas de R. stolonifer del 15,0% en presencia de la cepa Lv027, pero en ausencia de esta las esporangiosporas del fitopatógeno alcanzan un 92,0% de germinación. De acuerdo con los resultados presentados en los bioensayos, la concentración mínima efectiva de la cepa Lv027 es de 1x107células*ml-1 a 6°C y 20°C, la aplicación de la cepa Lv027, se debe realizar de forma preventiva con un mínimo tiempo de aplicación de 18 h. A partir de los resultados, también se evidencia fenómenos de competencia por nutrientes (carbohidratos) entre la cepa Lv027 de P. onychis frente a R. stolonifer, lo que se evidencia en el reducido desarrollo del micelio y baja germinación de las esporangiosporas del fitopatógeno en presencia de la cepa Lv027. Se sugiere, realizar futuros ensayos con esta levadura antagonista en condiciones comerciales de poscosecha de tomate.
Exploring the Correlation between Brazilian Iron Ore Exports and the Chinese Construction Sector
Authors: Rodrigues Daiane , Lengyel Peter 
Published: August 2023

A B S T R A C T

This article investigates the international iron trade, focusing on the Brazil-China network and its implications for economic and social progress. Iron supports various industries, particularly construction, manufacturing, and infrastructure development. The study employs descriptive analysis, quantitative measures, and correlation coefficients to analyse the dynamics of the iron trade. The research highlights Australia and Brazil as significant exporters in the global iron ore market, with China as the primary importer. Network analysis reveals China's extensive commercial connections and strong trade relationships with key exporting countries. Correlation coefficients demonstrate positive associations between Brazil's Iron Exports, Brazilian GDP, Chinese construction sector GDP, and world construction sector GDP, emphasising their interdependence. Understanding these dynamics is essential for policymakers, economists, and industry stakeholders in navigating the complexities of the global economy. The study provides valuable insights into the international iron trade, its impact on the construction sector, and broader economic dynamics. It contributes to informed decision-making and promotes sustainable economic and social development.
Snow Attenuation of Infrasound Signals and Wind Noise
Authors: Hoppinen Zachary , Johnson Jeffrey B. , Capelli Achille , Anderson Jacob H. , Marshall Hans-Peter 
Published: August 2023

Abstract
Infrasound monitoring of geophysical and human-sourced activity, such as explosions, eruptions, earthquakes, and avalanches, may be impacted by burial of sensors in a snowpack. We studied the frequency-dependent attenuation of sound, vertical sound speed, and wind noise reduction in a natural snowpack using earthquakes as a natural source of infrasound. Our experiment used a 2 m vertical distribution of sensors deployed during the 2021–2022 winter in the Sawtooth mountains of Idaho. We recorded 38 earthquakes and their primary infrasound propagating vertically upward through the snow. For these events, average attenuation appeared negligible between 0 and 8 Hz, rose to 0.1 dB/cm at ∼12 Hz, and remained at this level for higher frequencies. Using timing lags across the vertical profile the speed of infrasound in the snow was measured at 160 ± 51 m/s, significantly subsonic and indicative of pore-space waves. Finally, we quantified the significant reduction in the amount of background noise measured for snow-buried compared with free-air sensors. The 24 dB of reduction of noise observed for high wind speed conditions was evident with only 20 cm of snow burial and demonstrates the powerful capability of snowpack as a noise reduction filter. This study provides a clearer understanding of how snow burial filters infrasound and minimizes noise levels and has implications for monitoring of both natural and human-made hazards.
Specifics of Left Ventricular Hypertrophy and Characteristic of Phenotypic Variants in Patients with Hypertrophic Cardiomyopathy
Authors: Ignatenko G. I. , Taradin G. G. , Kugler T. E. 
Published: August 2023

Hypertrophic cardiomyopathy is characterized by genetic and phenotypic heterogeneity which manifests in different variants of localization and extent of myocardial hypertrophy.Aim: to evaluate specifics of left ventricular hypertrophy, the prevalence and characteristics of clinical and instrumental features of phenotypic variants of hypertrophic cardiomyopathy.Materials and methods. The study includes 295 patients with hypertrophic cardiomyopathy aged 18 to 88 years (60.3±13.4 years), 183 men (62 %), and women 112 (38 %). The diagnosis of which was established by 2D echocardiography. The severity, localization and extent of myocardial hypertrophy, the maximum thickness of the hypertrophied segment, left ventricular myocardial mass, left ventricular myocardial mass index, the presence and severity of mid-ventricular and left ventricular outflow tract obstruction were evaluated. Depending on the predominant localization and extent of hypertrophy, patients were divided into 8 groups according to the recommendations for hypertrophic cardiomyopathy of the Ministry of Health of the Russian Federation. The analysis and comparison of the obtained results are carried out.Results. The average duration of the disease is 10.5±7.52 years. The mean values of the body mass index in patients — 28.2±2.82 kg/m2. The phenotype with basal hypertrophy of the septum (n=130, 44.1 %), group 1 was most often noted. In 47 (15.9 %) patients, hypertrophy of the septum of “reverse curve” (2 group) was detected, in 41 (13.9 %) — “neutral septum” (3 group), in 36 (12.2 %) — symmetrical hypertrophy of the left ventricle (8 group), 11 (3.7 %) of patients had combined hypertrophy of the septum and other parts of the left or right ventricle (4 group) and the free left ventricular wall (7 group), in 10 (3.4 %) — middle ventricular hypertrophy of the left ventricle (6 group) and in 9 (3.1 %) — apical hypertrophy (5 group). The highest value of the maximum thickness of the myocardium was noted in patients of the 6th group 19.3 (1920.4 mm). Mid-ventricular obstruction was detected in group 6 (90 %), left ventricular outflow tract obstruction was more often registered in groups 4 and 8 (81.8 % and 77.8 %), and less often in group 5 (22.2 %) (p <0.01). In group 7, there were no cases of rest obstruction of left ventricular outflow tract. The maximum values of myocardial mass and left ventricular myocardial mass index were noted in group 8 — 402 (356-439) g and 195 (173218) g/m2, respectively (p <0.01).Conclusion. Echocardiography is an informative tool for assessing the presence, severity myocardial hypertrophy and determination of the phenotypic variant of hypertrophic cardiomyopathy. Variants of septal hypertrophy are most commonly registered one, among which the most frequent is the phenotype of basal septal hypertrophy. Each phenotype of hypertrophic expression is characterized by its echocardiographic parameters.