bluuebunny/crossref_metadata_2025_split huggingface dataset:
Atractivos turísticos de Ocaña y su región
Authors: Pacheco Carrascal Marilce , Vergel Quintero Damarys 
Published: March 2023

Tomando como referencia el estudio de la Capacidad Turística de Ocaña y su Región, se recurre a la información recolectada sobre los atractivos turísticos de Ocaña, La Playa de Belén, El Carmen y Ábrego en el Norte de Santander, como uno de los elementos que hacen parte de los recursos que permiten desarrollar la actividad turística, que dinamiza el desarrollo socioeconómico regional.
Para ello, se visitó cada uno de las poblaciones objeto de estudio donde se identificaron los atractivos turísticos con los que se cuenta, muchos de ellos declarados Bienes de Interés Cultural de Carácter Nacional, Departamental y Municipal; evidenciándose que Ocaña y su región posee un gran potencial turístico que permitiría ofertarse como un destino de clase mundial, pero para ello se requiere del apoyo e inversión tanto del sector público como del sector privado y el apoyo de instituciones educativas en la formación del recurso humano necesario que garantice un excelente servicio.
La importancia de la comunicación asertiva en el direccionamiento estratégico y ejecución de los proyectos
Authors: Silva Giraldo Cesar Augusto , Mejia Jálabe Aizar , Suarez David Andrés 
Published: March 2023

El siguiente artículo presenta una reflexión acerca la importancia de la comunicación asertiva en el direccionamiento estratégico y ejecución de proyectos resaltando la importancia de la comunicación como un proceso vital y parte inherente al ser humano, se apoya en una serie de autores que dan soporte desde una mirada de las prácticas comunicacionales existentes de tipo positivo o negativo convirtiéndose entonces, en elemento orientador y que puede ser empleado asertivamente por gerentes en las diferentes organizaciones o contextos laborales, también se retoman conceptos tales como asertividad en la comunicación vista como una destreza social, por medio de la cual se muestran ideas, opiniones y sentimientos de forma clara, directa, equilibrada, honesta y respetuosa entre otros. Finalmente se menciona el valor de la gestión de la comunicación asertiva como una herramienta de vital relevancia que deben potencializar los gerentes de las organizaciones desde la planeación y el direccionamiento estratégico con el fin de poder garantizar ventajas competitivas, a través del desarrollo de prácticas efectivas de liderazgo y la integración total.
METTL3 promotes PGC-1α transcription and alleviates mitochrondrial dysfunction of diabetic nephropathy by targeting lncRNA TUG1 m6A modification
Authors: Chen Tong , Wang Juan , Xu Yanyan , Zhu Yonghong , Ying Jin , Fan Qiuling 
Published: March 2023

Background: m6A modification plays an important role in various
biological processes and can regulate the function of non-coding RNA.
Our research group found the m6A level of lncRNA TUG1 was reduced in
HK-2 cells cultured with high glucose. Here we study the impact of the
important component of m6A-METTL3 on TUG1 in diabetic nephropathy.
Objective: Explore the m6A modification mechanism of lncRNA TUG1 and
whether METTL3 can promote PGC-1α transcription, alleviate
mitochrondrial dysfunction and diabetic renal injury. Methods: Test the
m6A modification level of the total RNA and lncRNA TUG1 in HK-2 cells
and db/db mice.Detect whether lncRNA TUG1 can combine METTL3 and IGF2BP2
by RIP-PCR. Test the mitochondrial function HK-2 cells and db/db mice.
Use transmission electron microscope to observe the morphology of
mitochondria in HK-2 cells and db/db mice. Results: RIP-PCR showed that
lncRNA TUG1 could bind to METTL3, and IGF2BP2 could recognize the
m6A-modified lncRNA TUG1. IGF2BP2 improved the stability of lncRNA TUG1.
High glucose and transfection of siTUG1 in HK-2 cells inhibited PGC-1α
pathway, and aggravated mitochondrial dysfunction and morphological
damages, while overexpression of METTL3 in HK-2 cells and injection of
AAV-METTL3 in db/db mice partially rescued the negative effect.
Conclusion: RNA m6A methylation/demethylation imbalance may be mainly
regulated by METTL3 in HK-2 cells, and involved in the occurrence and
development of diabetic nephropathy. METTL3 can promote the expression
of TUG1 through m6A modification in a IGF2BP2-dependent manner in HK-2
cells, and regulate the PGC-1α pathway to alleviate mitochrondrial
dysfunction of diabetic nephropat
Integral Risk Assessment in Steel Ropes Diagnostics Using Computer Vision
Authors: Panfilov A. V. , Nikolaev N. N. , Yusupov A. R. , Korotkiy A. A. 
Published: March 2023

Introduction. Currently, the technical condition of ropes of cable-working machines is evaluated periodically according to regulatory documentation. At the same time, methods of visual and instrumental control are used, which depend on the skills and physical capabilities (vision) of the personnel performing the work. There is no unified system of continuous assessment of the technical condition based on a set of factors that does not depend on the human factor. As a result, emergencies occur even when all routine maintenance is carried out on time. To correct this situation, it is proposed to use a computer vision system and neural networks, which allows determining its suitability for further operation by risk levels based on the totality of detected and identified defects, with the interpretation of their results in the color scheme: green — acceptable, yellow — increased, red — high. The work objective is to propose an integral method for risk assessment of operating machines with rope traction when defects and their combinations are detected in a steel rope using computer vision while excluding the influence of the human factor. Materials and Methods. Training of the neural network was carried out on the basis of statistical data of defects obtained from the results of technical inspections of machines with rope traction, on sections of the rope, multiples of its six and thirty nominal diameters according to GOST 33 718. Indexing of risks in the color scheme was carried out according to GOST 55 234.3 to develop a strategy for steel ropes maintenance. A certificate of registration of a computer program was obtained for the neural network program code. The neural network processes visual and measurement control data based on computer vision. Results. An integrated risk assessment system has been created for the diagnosis of steel ropes using computer vision, which allows you to detect defects in steel ropes timely, assess the existing risk of further operation and give recommendations to specialists of operating organizations in real time. This will dramatically reduce the risk of accidents, injury and death of people at facilities using steel ropes. Discussion and Conclusion. The proposed integrated risk assessment system can be applied in any facility that uses rope traction. These are elevators for various purposes, funiculars, cable cars, cranes and many other machines. It should be noted that the estimated commercial cost of the system is low; therefore, the system is available to a wide range of consumers.
Ejemplaridad en los escenarios de la convergencia mediática
Authors: Sarapura Sarapura Mercedes Milagro 
Published: March 2023

Los escenarios de la convergencia son los espacios actuales donde se propicia la tensión entre dos dimensiones contrastantes de acuerdo a la mirada de Gomá, la del estadio estético y la del estadio ético. Es en esa atmósfera donde la comunicación entendida como influencia personal en grupos pequeños cobra relevancia y vuelve a dar vigencia y un renovado rostro al clásico paradigma de los dos pasos, propuesto por Lazarsfeld en los inicios de la investigación científica de los medios de la comunicación en Norteamérica.
Los grupos y sus líderes interactúan intensamente ahora en las redes sociales; los líderes surgen entre ellos y causan influencia. La presente investigación cualitativa aborda desde la perspectiva de la ejemplaridad propuesta por Javier Gomá, la importancia de la influencia personal y los referentes en la vida cotidiana de miles de millones de personas a través de las redes sociales y su impacto en la realidad offline.
El caso de las múltiples adaptaciones
Authors: Mazzeo Vanesa Paola 
Published: March 2023

Desde 1900 cuando se estrena la primera producción audiovisual con el nombre Sherlock Holmes Baffled, no sólo se adaptaron y modernizaron los personajes canónicos de los 60 casos escritos por Sir Arthur Conan Doyle, sino que se realizaron crossover con otras historias y hasta se han ido incorporado nuevos integrantes a la familia. Para analizar las adaptaciones audiovisuales de las historias del detective consultor único en el mundo, se necesita: seleccionar algunas de las producciones y establecer una serie de conceptos sobre los cuales trabajar.
Tomaremos en consideración cuatro adaptaciones audiovisuales: Sherlock Holmes (Granada), Sherlock, Elementary y Enola Holmes. Estas producciones están relacionadas a diferentes momentos de la pantalla chica y sirven como excusa para poder analizar y comparar cómo se han modificado y actualizando los elementos del universo narrativos del canon holmesiano a partir de cinco variables: los eventos, los personajes, el tiempo, el universo narrativo y las prácticas de consumo, siempre teniendo en cuenta el contexto en que se estrenaron las adaptaciones del canon
Creatividad en la restricción
Authors: Sandoval Laura Emilce , Moreira Alonso Joaquín 
Published: March 2023

Los memes de internet son una de las formas comunicacionales participativas más características de la web 2.0. Con el objetivo de ser humorísticos pero también expresar sentimientos, ideas y opiniones de formas creativas y ser fácilmente comprensibles, los usuarios crean memes basados en formatos preexistentes llamados usualmente templates. En este artículo analizamos el uso de templates en memes de imagen fija desde una perspectiva empírica y teórica y también otras maneras en las que los memes están estructurados semióticamente por formas preexistentes.
Lectora de la existencia
Authors: Argüello Guzmán Luis Alfonso 
Published: March 2023

El presente artículo tiene un propósito fundamental centrado en estudiar los modos en los que Iris Murdoch se enfrenta a los textos literarios y filosóficos que la desafían e inspiran su propia obra ensayística, a la vez que elabora un modelo de análisis y reflexión como lectora. Este análisis se restringe a una selección de sus propios ensayos, artículos y textos filosóficos. Este artículo se ha dividido en tres secciones. La primera asume la relación establecida por Murdoch entre filosofía y literatura como un modo de leer que permite el encuentro entre moral y novela. La segunda se ocupa de la novela existencialista como modo de comprensión narrativa del mundo a partir de la individualidad de la existencia de lo humano. La tercera se concentra en la contemplación platónica sobre la mímesis y la realidad.
Nostalgias del futuro
Authors: Bustingorry Florencia 
Published: March 2023

Este trabajo tiene como objetivo analizar cuáles son los recursos a través de los cuales se construye una noción de futuro en el discurso de los medios, en el contexto de la pandemia del covid-19. Haremos hincapié en los siguientes interrogantes: ¿Cuál es el imaginario de futuro que se construye a través de los discursos de los medios de comunicación? ¿cómo se vinculan pasado, presente y futuro en las perspectivas que plantean los medios? ¿qué idea de normalidad se construye en el discurso mediático?
Nuestra hipótesis es que hay una persistencia de un pensamiento ligado a la modernidad, una búsqueda de estabilidad, de cierta normalidad, que se ha visto puesta en duda a partir de la aparición del coronavirus. La amenaza de la pandemia ha puesto en cuestión algunas certezas que se creían tener sobre el futuro y ha supuesto una acentuada idealización del pasado, con una idea de que eramos libres/felices y no lo sabíamos.
Analizamos 15 titulares BBC Mundo en español en su versión digital desde marzo hasta octubre de 2020, en la sección salud, para reflexionar cómo un medio internacional construye sentidos sobre este fenómeno global. La elección de este medio de comunicación responde a una muestra evaluada y de oportunidad.
The Puduhush gabbro in Griqualand West, South Africa: extendingca.1.89 to 1.83 Ga intraplate magmatism across the proto-Kalahari Craton
Authors: Ncube S. , Wabo H. , Owen-Smith T.M. , Gumsley A.P. , Beukes N.J. 
Published: March 2023

AbstractThe Puduhush gabbro is located on the western margin of the proto-Kalahari Craton in Southern Africa. This gabbro intrudes the Volop Formation, which conformably overlies the Hartley Formation lava of the late Palaeoproterozoic Olifantshoek Group. Here we report a new U-Pb ID-TIMS baddeleyite age as well as petrographic, whole-rock geochemical and palaeomagnetic results for the Puduhush gabbro. The gabbro shows a well-preserved sub-ophitic texture between clinopyroxene and plagioclase, with minor amounts of amphibole, olivine, biotite and Fe-Ti oxides. The new U-Pb ID-TIMS baddeleyite age of 1 881 ± 1 Ma reported here for the Puduhush gabbro, together with existing ages for the Hartley Formation, define a ca.1 916 to 1 881 Ma age bracket for the Volop Formation. Our 1 881 ± 1 Ma age is also within error of ages reported for the oldest episode (so-called Episode 1) of the ca.1.89 to 1.83 Ga magmatism in the eastern and northern parts of the proto-Kalahari Craton. Our geochemical results also suggest compositional similarities between the Puduhush gabbro and Episode 1 magmatism, particularly the post-Waterberg sills. The virtual geomagnetic pole calculated here for the Puduhush gabbro (VGP: 1.6°N; 352.0°E; A95 = 14.2°) is consistent with the Episode 1 pole. All data are therefore combined to produce a new palaeomagnetic pole (11.7°N; 8.8°E, A95 = 9.3°) for Episode 1 magmatism. The present study provides the first evidence that the ca.1.89 to 1.83 Ga magmatism had a wider footprint that previously thought, extending to the western margin of the proto-Kalahari Craton. This wide-scale magmatism, previously proposed to be related to a back-arc extension setting, is here reinterpreted in the context of a mantle plume. Our results are consistent with the lithostratigraphic-based notion that at least parts of the red-bed successions (i.e., Olifantshoek and Waterberg Groups) that are hosts to the ca.1.89 to 1.83 Ga magmatism could be correlative units, representing an extensive sedimentary sequence that once covered large expanses of the proto-Kalahari Craton.
Fatigue analysis of brazing structures with fin-plate-side bar in Liquefied Natural Gas (LNG) heat exchangers under cryogenic conditions
Authors: Ma Hongqiang , Jia Jiwei , Liu Yu , Luo Xinmei , Hou Caiqin , Wang Gang 
Published: March 2023

The purpose of this study is to evaluate the fatigue life of heat exchangers used for Liquefied Natural Gas (LNG) and to ensure its structural safety, the alternating stress of brazing structures under cryogenic conditions was analyzed with a Finite Element Model (FEM). Stress concentrations occurred at the brazed joint with a maximum alternating stress amplitude of 153.45 MPa. The fatigue life of brazed structures during the continuous cool-down and heat-up conditions was evaluated based on the ASME standard and the maximum alternating stress amplitude. Meanwhile, structure parameters have been analyzed for their influence on fatigue life. There are four main structure factors to influence the life cycle: the brazing seam, the fin thickness, the fin distance, and the fin height. The life cycle will decrease with increasing the fin distance, fin height, and brazing seam thickness, and it will increase with increasing the fin thickness. In addition, in order to predict fatigue life, a calculating model has been established based on the main factors. Finally, the fatigue life of brazing structures was also tested by experiment, and the microstructure was also analyzed for the fatigue fracture surface. It is clear that brittle fractures along the brazing seam and ductile fractures at the fin roots should be the primary failure modes. The study provides a base for LNG aluminum heat exchanger design, manufacture, and safe operation.
Administração de Rituximab e manejo de reações adversas em serviços de oncologia
Authors: Paixão Wallace Henrique Pinho da , Corrêa Daiana Neiva de Paula , Oliveira Erilane de Almeida Aguiar , Paula Hermes Candido de , Braga Tamires Santos , Silva Amanda Santana Goes da , Brandão Paula Paraguassú , Sousa Cristiane Moreira de , Silva David Costa da , Barbosa Kessya Cristina Valentim 
Published: March 2023

Objetivo: Identificar quais são os principais cuidados na administração do Rituximab, bem como apontar as principais condutas diante de reações infusionais em serviços de oncologia. Métodos: Revisão integrativa da literatura que buscou estudos nos portais e bases de dados BVS, LILACS, MEDLINE, e Google Scholar e utilizou os seguintes critérios de inclusão: texto completo disponível, publicado entre os anos 2016 e 2021, nos idiomas português, inglês e espanhol. Resultados: Foram selecionados 11 artigos que foram discutidos em três categorias, a saber: Infusão de primeira vez e subsequentes; Cuidados na infusão; Administração de Rituximab e reações adversas: assistência de enfermagem. Considerações finais: As reações gerais, já são bem descritas na literatura, contudo, os mecanismos e fatores de risco que favorecem o acontecimento, ainda são escassos. É de fundamental importância que o enfermeiro possua conhecimento no manejo das reações infusionais relacionadas ao Rituximab e destreza para intervir rapidamente diante de tais situações.
Violência obstétrica no contexto da depressão pós-parto
Authors: Vargas Jenifer Ferreira de , Salcher Fernanda Gava 
Published: March 2023

Objetivo: Identificar fatores associados à violência contra gestantes e sua influencia na depressão pós-parto. Métodos: Revisão integrativa da literatura. A coleta de dados foi feita através de uma busca na literatura nas bases de dados SCIELO, LILACS e BVS. A avaliação e a análise dos dados foram realizadas através da leitura dos artigos. Resultados: Inicialmente, foram encontrados 112.021 artigos. Após a aplicação dos filtros e da leitura dos resumos, foram excluídos 1.371 artigos que não se encaixavam dentro dos fatores de inclusão, restando 15 para a realização do estudo. Ao final do processo de revisão, os artigos evidenciaram os principais fatores associados a tipos de violência obstétrica e a sua influencia na depressão-pós-parto, e o papel dos enfermeiros no processo, e as principais ações para uma assistência de humanização no ciclo gravídico/puerperal. Considerações finais: A violência obstétrica está presente em grande parte das instituições e pode se manifestar de diversas maneiras. É evidente a necessidade de mudanças. Os enfermeiros possuem papel fundamental para que essas mudanças aconteçam, pois com assistência de qualidade são capazes de minimizar o prodesso da violência obstétrica e os danos decorrentes dela no processo.
Comparison of arterial spin labeling perfusion with dynamic susceptibility contrast perfusion in Moyamoya disease
Authors: Yadav Nishtha , Pendharkar Hima , Gupta Arun kumar , Prasad Chandrajit , Shukla Dhaval , Kandavel Thennarasu , Bansal Sonia 
Published: March 2023

Objectives:
Moyamoya disease (MMD) leads to frequent ischemic/hemorrhagic manifestations. Our aim was to compare findings of arterial spin labeling (ASL) with dynamic susceptibility contrast (DSC) perfusion in patients of MMD

Materials and Methods:
Patients diagnosed as MMD underwent magnetic resonance imaging with ASL and DSC perfusion sequences. Perfusion in bilateral anterior cerebral artery and middle cerebral artery territories at two levels (level of thalami and centrum semiovale) was graded as normal (score 1), or reduced (score 2) on DSC and ASL cerebral blood flow (CBF) maps by comparison with normal cerebellar perfusion. Time to peak (TTP) maps of DSC perfusion were also qualitatively scored as normal (score 1), or increased (score 2) similarly. Correlation between scores of ASL, CBF, DSC, CBF, and DSC, TTP maps was assessed by using Spearman’s rank correlation.

Results:
Among the 34 patients, we did not find any significant correlation between the ASL CBF maps and DSC CBF maps (r = −0.028, P = 0.878), mean matching index 0.39 ± 0.31, whereas significant correlation was noted between the ASL CBF maps and DSC TTP maps (r = 0.58, P = 0.0003), mean matching index 0.79 ± 0.26. ASL CBF underestimated the perfusion compared to DSC perfusion.

Conclusion:
ASL perfusion CBF maps do not match the DSC perfusion CBF maps and rather match the TTP maps of DSC perfusion. This is explained by inherent problems in estimation of CBF in these techniques because of delay in arrival of label (in ASL perfusion) or contrast bolus (in DSC perfusion) due to the presence of stenotic lesions.
Citrobacter koseri: A rare cause of an epidural spinal abscess
Authors: Casas-Martínez Martín R. , Rodríguez-Rubio Héctor A. , Bonilla-Suastegui Alfredo , López-Rodríguez Rodrigo , Serrano-Rubio Alejandro , Montes-Aguilar Oscar Josue , Alvarez-Betancourt Leonardo , Morgado-Vazquez Jonathan Samuel 
Published: March 2023

Background:
Citrobacter koseri, a Gram-negative organism, rarely causes an epidural spinal abscess.

Case Description:
A 50-year-old male presented with mild paraparesis attributed to an magnetic resonance (MR)-documented spinal epidural abscess (SEA) at the T10-level. Following surgical debridement, cultures grew C. koseri, a rare Gram-negative organism. The abscess was subsequently managed with a prolonged course of antibiotics resulting in complete symptom and MR-documented radiological resolution.

Conclusion:
A 50-year-old male presented with a T10 SEA attributed to a rare Gram-negative organism, C. koseri. The abscess was appropriately managed with surgical decompression/debridement, followed by prolonged antibiotic therapy.
Detection of ictal and periictal hyperperfusion with subtraction of ictal-interictal 1.5-Tesla pulsed arterial spin labeling images co-registered to conventional magnetic resonance images (SIACOM)
Authors: Abe Keisuke , Shimogawa Takafumi , Mukae Nobutaka , Ikuta Koumei , Shono Tadahisa , Tanaka Atsuo , Sakata Ayumi , Shigeto Hiroshi , Yoshimoto Koji , Morioka Takato 
Published: March 2023

Background:
Our recent report showed that 1.5-T pulsed arterial spin labeling (ASL) magnetic resonance (MR) perfusion imaging (1.5-T Pulsed ASL [PASL]), which is widely available in the field of neuroemergency, is useful for detecting ictal hyperperfusion. However, the visualization of intravascular ASL signals, namely, arterial transit artifact (ATA), is more remarkable than that of 3-T pseudocontinuous ASL and is easily confused with focal hyperperfusion. To eliminate ATA and enhance the detectability of (peri) ictal hyperperfusion, we developed the subtraction of ictal-interictal 1.5-T PASL images co-registered to conventional MR images (SIACOM).

Methods:
We retrospectively analyzed the SIACOM findings in four patients who underwent ASL during both (peri) ictal and interictal states and examined the detectability for (peri) ictal hyperperfusion.

Results:
In all patients, the ATA of the major arteries was almost eliminated from the subtraction image of the ictal-interictal ASL. In patients 1 and 2 with focal epilepsy, SIACOM revealed a tight anatomical relationship between the epileptogenic lesion and the hyperperfusion area compared with the original ASL image. In patient 3 with situation-related seizures, SIACOM detected minute hyperperfusion at the site coinciding with the abnormal electroencephalogram area. SIACOM of patient 4 with generalized epilepsy diagnosed ATA of the right middle cerebral artery, which was initially thought to be focal hyperperfusion on the original ASL image.

Conclusion:
Although it is necessary to examine several patients, SIACOM can eliminate most of the depiction of ATA and clearly demonstrate the pathophysiology of each epileptic seizure.