bluuebunny/crossref_metadata_2025_split huggingface dataset:
Myeloproliferative neoplasms and splanchnic vein thrombosis: Contemporary diagnostic and therapeutic strategies
Authors: Kiladjian Jean‐Jacques , Cassinat Bruno 
Published: March 2023

AbstractMyeloproliferative neoplasms (MPNs) are the most common etiologies of primary splanchnic vein thrombosis, present in almost forty percent of patients with Budd‐Chiari syndrome or portal vein thrombosis. Diagnosis of MPNs can be difficult in these patients because key characteristics, such as elevated blood cell counts and splenomegaly, are confounded by portal hypertension or bleeding complications. In recent years, diagnostic tools have improved to provide more accurate diagnosis and classification of MPNs. Although bone marrow biopsy findings remain a major diagnostic criterion, molecular markers are playing an increasing role not only in diagnosis but also in better estimating prognosis. Therefore, though screening for JAK2V617F mutation should be the starting point of the diagnostic workup performed in all patients with splanchnic vein thrombosis, a multidisciplinary approach is needed to accurately diagnose the subtype of myeloproliferative neoplasm, recommend the useful additional tests (bone marrow biopsy, search for an additional mutation using targeted next‐generation sequencing), and suggest the best treatment strategy. Indeed, providing a specific expert care pathway for patients with splanchnic vein thrombosis and underlying myeloproliferative neoplasm is crucial to determine the optimal management to reduce the risk of both hematological and hepatic complications.
Selective Synthesis of Benzofuro[2,3‐c]isoquinolines and 5,6‐Dihydro‐7H‐benzo[c]benzofuro[2,3‐e]azepin‐7‐ones from 4‐Diazoisoquinolin‐3‐ones and Salicylaldehydes
Authors: Chen Junrong , Suleman Muhammad , Lu Ping , Wang Yanguang 
Published: March 2023

AbstractA catalyst‐controlled selective synthesis of benzofuro[2,3‐c]isoquinolines and 5,6‐dihydro‐7H‐benzo[c]benzofuro[2,3‐e]azepin‐7‐ones from salicylaldehydes and 4‐diazoisoquinolin‐3‐ones has been developed. The Co(III)‐catalyzed reactions furnished benzofuro[2,3‐c]isoquinolines as major products, while the Rh(III)‐catalyzed reactions afforded 5,6‐dihydro‐7H‐benzo[c]benzofuro[2,3‐e]azepin‐7‐ones as major products.
Multiphonon Bundle Emission in a Strong‐Coupling Cavity Optomechanical System
Authors: Deng Tong‐Hui , An Xing‐Wei , Lan Zi‐Liang , Chen Lei , Ye Sai‐yun , Zhong Zhi‐Rong 
Published: March 2023

AbstractNonclassical effects in mesoscopic systems have attracted much attention recently. In this paper, it is shown that multiphonon bundle emission can be observed in a strong‐coupling cavity optomechanical system. Theoretical analysis shows that when the driving field is adjusted to nth‐order sideband excitation, the coupling between the cavity mode and the vibrational mode leads to super‐Rabi oscillations, and finally results in an n‐phonon bundles emission. Based on the current technology, this process can work in a wide range of parameters. Numerical simulation confirms the validity of the derivation. It is thought that this physical mechanism broadens the applications of cavity optomechanical system in realm of quantum phononics, such as in quantum metrology and phonon laser.
Asymmetric Construction of α,α‐Disubstituted Piperazinones Enabled by Benzilic Amide Rearrangement
Authors: He Yu‐Ping , Quan Rui , Li Xing‐Zi , Zhu Jieping , Wu Hua 
Published: March 2023

AbstractAn unprecedent asymmetric catalytic benzilic amide rearrangement for the synthesis of α,α‐disubstituted piperazinones is reported. The reaction proceeds via a domino [4+1] imidazolidination/formal 1,2‐nitrogen shift/1,2‐aryl or alkyl migration sequence, employing readily available vicinal tricarbonyl compounds and 1,2‐diamines as starting materials. This approach provides an efficient access to chiral C3‐disubsituted piperazin‐2‐ones with high enantiocontrol, which are exceedingly difficult to access from the existing synthetic methodologies. The observed enantioselectivity was proposed to be controlled by dynamic kinetic resolution in the 1,2‐aryl/alkyl migration step. The resulting densely functionalized products are versatile building blocks to bioactive natural products, drug molecules and their analogues.
Dynamic‐to‐Static Planar Chirality Conversion in Pillar[5]arenes Regulated by Guest Solvents or Amplified by Crystallization
Authors: Wada Keisuke , Suzuki Misaki , Kakuta Takahiro , Yamagishi Tada‐aki , Ohtani Shunsuke , Fa Shixin , Kato Kenichi , Akine Shigehisa , Ogoshi Tomoki 
Published: March 2023

AbstractControlling dynamic chirality and memorizing the controlled chirality are important. Chirality memory has mainly been achieved using noncovalent interactions. However, in many cases, the memorized chirality arising from noncovalent interactions is erased by changing the conditions such as the solvent and temperature. In this study, the dynamic planar chirality of pillar[5]arenes was successfully converted into static planar chirality by introducing bulky groups through covalent bonds. Before introducing the bulky groups, pillar[5]arene with stereogenic carbon atoms at both rims existed as a pair of diastereomers, and thus showed planar chiral inversion that was dependent on the chain length of the guest solvent. The pS and pR forms, regulated by guest solvents, were both diastereomerically memorized by introducing bulky groups. Furthermore, the diastereomeric excess was amplified by crystallization of the pillar[5]arene. The subsequent introduction of bulky groups yielded pillar[5]arene with an excellent diastereomeric excess (95 % de).
Heterobimetallic NiFe Cooperative Molecular Water Oxidation Catalyst
Authors: Zhang Hong‐Tao , Guo Yu‐Hua , Xiao Yao , Du Hao‐Yi , Zhang Ming‐Tian 
Published: March 2023

AbstractWe reported herein the development of heterobimetallic NiFe molecular platform to understand NiFe synergistic effect in water oxidation catalysis. Compared to homonuclear bimetallic compounds (NiNi and FeFe), NiFe complex possesses more remarkable catalytic water oxidation performance. Mechanistic studies suggest that this remarkable difference is attributed to the fact that NiFe synergy can effectively promote O−O bond formation. The generated NiIII(μ‐O)FeIV=O is the key intermediate and O−O bond was formed via intramolecular oxyl‐oxo coupling between bridged O radical and terminal FeIV=O moiety.
In situ Nucleation‐Growth Strategy for Controllable Heterogeneous Supramolecular Polymerization of Liquid Crystalline Block Copolymers and Their Hierarchical Assembly
Authors: Jin Bixin , Li Qin , Hu Lingjuan , Liu Qianwei , Chen Yiqi , Luo Yunjun , Chi Shumeng , Li Xiaoyu 
Published: March 2023

AbstractThe self‐assembly morphologies of subunits are largely governed by thermodynamics, which plays a less important role in dimensional control. Particularly for one‐dimensional assemblies from block copolymers (BCPs), the negligible energy difference between short and long ones imposes great challenges in length control. Herein, we report that by incorporating additional polymers to induce in situ nucleation and trigger the subsequent growth, controllable supramolecular polymerization driven by mesogenic ordering effect could be realized from liquid crystalline BCPs. The length of the resultant fibrillar supramolecular polymers (SP) is controlled by tuning the ratio between nucleating and growing components. Depending on the choice of BCPs, the SPs can be homopolymer‐like, heterogeneous triblock, and even pentablock copolymer‐like. More interestingly, with insoluble BCP as a nucleating component, amphiphilic SPs are fabricated, which can undergo spontaneous hierarchical assembly.
Uniform Growth of Nanocrystalline ZIF‐8 on Cellulose Nanocrystals: Useful Template for Microporous Organic Polymers
Authors: Cho Kyoungil , Andrew Lucas J. , MacLachlan Mark J. 
Published: March 2023

AbstractZeolitic imidazolate framework (ZIF‐8) nanocrystals were uniformly grown on the surface of cellulose nanocrystals (CNCs) to give a hybrid material, ZIF@CNCs. By varying the stoichiometry of the components, it was possible to control the size of the ZIF‐8 crystals grown on the CNC surface. Optimized ZIF@CNC (ZIF@CNC‐2) was used as a template to synthesize a microporous organic polymer (MOP), ZIF@MOP@CNC. After etching the ZIF‐8 with 6 M HCl solution, a MOP material with encapsulated CNCs (MOP@CNC) was formed. Zinc coordination into the porphyrin unit of the MOP yielded the ship‐in‐a‐bottle structure, Zn MOP@CNC, comprised of CNCs encapsulated within the Zn‐MOP. In comparison to ZIF@CNC‐2, Zn MOP@CNC showed better catalytic activity and chemical stability for CO2 fixation, converting epichlorohydrin to chloroethylene carbonate. This work demonstrates a novel approach to create porous materials through CNC templating.
A Polarized Gel Electrolyte for Wide‐Temperature Flexible Zinc‐Air Batteries
Authors: Jiao Miaolun , Dai Lixin , Ren Hong‐Rui , Zhang Mengtian , Xiao Xiao , Wang Boran , Yang Jinlong , Liu Bilu , Zhou Guangmin , Cheng Hui‐Ming 
Published: March 2023

AbstractThe development of flexible zinc‐air batteries (FZABs) has attracted broad attention in the field of wearable electronic devices. Gel electrolyte is one of the most important components in FZABs, which is urgent to be optimized to match with Zn anode and adapt to severe climates. In this work, a polarized gel electrolyte of polyacrylamide‐sodium citric (PAM‐SC) is designed for FZABs, in which the SC molecules contain large amount of polarized −COO−functional groups. The polarized −COO−groups can form an electrical field between gel electrolyte and Zn anode to suppress Zn dendrite growth. Besides, the −COO−groups in PAM‐SC can fix H2O molecules, which prevents water from freezing and evaporating. The polarized PAM‐SC hydrogel delivers a high ionic conductivity of 324.68 mS cm−1and water retention of 96.85 % after being exposed for 96 h. FZABs with the PAM‐SC gel electrolyte exhibit long cycling life of 700 cycles at −40 °C, showing the application prospect under extreme conditions.
Engineering Graphdiyne for Solar Photocatalysis
Authors: Li Jian , Zhu Lei , Tung Chen‐Ho , Wu Li‐Zhu 
Published: March 2023

AbstractGraphdiyne (GDY) with a direct band gap, excellent carrier mobility and uniform pores, is regarded as a promising photocatalytic material for solar energy conversion, while the research on GDY in photocatalysis is a less developed field. Herein, the distinctive structure, adjustable band gap, and electronic properties of GDY for photocatalysis is firstly summarized. The construction and progress of GDY‐based photocatalysts for solar energy conversion, including H2 evolution reaction (HER), CO2 reduction reaction (CO2RR) and N2 reduction reaction (NRR) are then elaborated. At last, the challenges and perspectives in developing GDY‐based photocatalysts for solar fuel production are discussed. It is anticipated that a timely Minireview will be helpful for rapid progress of GDY in solar energy conversion.
Outline of the conceptual evolution of the CEFYP*
Authors: Esborraz Alejandra 
Published: March 2023

AbstractThis article presents a historical journey through the concepts developed (i.e., worked, modified, and made more complex) over four decades in the existence of one of the first family therapy institutions in Argentina: the CEFYP. This journey travels from its beginnings, in the midst of the military dictatorship, to the present. The concepts will be introduced and discussed taking into account those concepts that emerged and stood out as we worked therapeutically, enriching our clinic in each new paradigm. We will start from the CEFYP's emergence within the socio‐political framework of Argentina in the 1970s, its constitution as differentiated from the prevailing psychoanalytic context within the field of psychotherapies, and its evolution, an evolution that was always attentive to the particular questions that accompanied its relational approach. These questions, which intersected philosophy, anthropology, art, and critical history, will express the position of the CEFYP in relation to change, history, power, dialogue, and the therapist and their place in the process of change. Finally, it will also discuss the CEFYP's way of thinking and developing the teaching and training of relational systemic therapists. This article will also present the most outstanding clinical themes, exemplified with the use of vignettes. Among others, these include our trajectories in the clinic of violence and partner violence, the clinic in destructive divorces, and the clinic with seriously disturbed families.
A short review on recent advances in porous adsorbents for separation of oxygen from atmospheric air
Authors: Shrotri Aadesh R. , Niphadkar Prashant S. , Bokade Vijay V. , Utgikar Vivek P. , Nandanwar Sachin U. 
Published: March 2023

AbstractPure oxygen demand is continuously increasing worldwide due to wide applications including medical and industrial. Pressure swing adsorption (PSA) is one of the promising techniques to separate O2 from atmospheric air. The porous solid adsorbent is a key element in the PSA to trap nitrogen (N2) and release O2. Several adsorbents including low silica X (LSX), zeolite 5A, ion‐exchanged LSX (Li‐LSX, AgLi‐LSX, Ca‐LSX), Engelhard titanosilicate (Na‐ETS‐10, Ag‐ETS‐10), and SSZ‐13 have been investigated for adsorption of N2 from the air. This review article is a summarization of recent research work published on O2 separation using different porous adsorbents via PSA. This review also emphasizes on the best porous sorbent for purification of O2 by sorption of N2 and Ar. The adsorption capacities with experimental conditions are also rigorously discussed. The review also proposed future trends and prospects for O2 separation. This review will be helpful to choose remarkable adsorbent for the generation pure O2.
Study on zinc oxide‐creatinine hybrid catalyst for efficient lactide synthesis with low racemization
Authors: Tian Guiying , Wang Huiqing , Song Yuanyuan , Xiang Jun , Ying Yiran , Han Xurui , Wang Songbo , Zhang Lei , Zhang Jianping , Tang Na 
Published: March 2023

AbstractLactide is the crucial intermediate for polylactic acid (PLA) synthesis via ring‐open polymerization, but it suffers low yield and low purity induced by racemization reaction. In this work, we have developed a zinc oxide‐creatinine (ZnO‐CR) hybrid catalyst, which offers high yield (the distilled lactide yield and pure l‐lactide yield are 95.73% and 61.64%) and high purity (81.53%) for green l‐lactide synthesis at the cyclization temperature of 240°C. Furthermore, NMR and HPLC results show that CR addition significantly restrains the racemization by reducing α‐proton abstraction, where guanidine derived from the CR plays a main catalytic role to provide a tight association with the carbonyl oxygen in the carboxyl of LnA oligomers. Therefore, carbonyl‐carbon with the enhanced electrophilicity is easier being attacked by a hydroxyl terminal of LnA oligomers, leading to high yield and high purity for lactide synthesis.
Synthesis and characterization of poly [(3,4‐ethylenedioxy) thiophene]:polystyrene sulfonate (PEDOT:PSS) for energy storage device application
Authors: Goyal Megha , Agarwal Satya Narayan , Singh Kulwant , Bhatnagar Nitu 
Published: March 2023

AbstractIn this paper, the facile synthesis and characterization aspects of PEDOT:PSS has been presented, in the context of energy storage device technology. PEDOT/PSS particles were synthesized via chemical oxidative polymerization to improve the electrical conductivity. The mechanism for this conductivity enhancement was studied through various chemical and physical characterizations. The structural characterization establishes that all the samples have high surface area and are highly crystalline, showing 3–4 nm spherical nanoparticles with the smoother surface. The electrical conductivity of measured thin film reached 6.23 × 10−6 ℧ cm−1. The use of the PEDOT:PSS as a binders will surely be helpful for scaling up the energy storage technology like high electrical conductivity, the ability for aqueous processing, electrochemical performance, good electrochemical stability and shows good binding ability. It also helps to protect the energy storage devices against electrode particle cracking, solid electrolyte interface (SEI), dendrite formation or lithium plating.
Electrothermal properties of short carbon fiber/PLA composite structure and its fast response behavior
Authors: Lin Liulan , Liu Guomin , Xu Weixuan 
Published: March 2023

AbstractIn this study, a new short carbon fiber (SCF) composite structure with electric triggering shape memory properties is developed. The SCF is cast on poly (lactic acid) substrate, then encapsulated by polyvinyl alcohol after drying and molding. In the experiment, the conductivity of the short carbon fiber/PLA sample with 5 mm conductive soft segment and 0.1 mm thickness diamond grid reached the 87.3 S/m, and the temperature of the substrate is higher than its glass transition temperature under 3 V voltage, indicating that the electric heating manner is feasible and stable. The shape recovery rate of the composite structure reaches 91.36%, and the shape memory deformation time is 18 s. This study provides a low‐cost and efficient preparation method for SCF reinforced composite structure, which is promoting the development and application of electric triggering shape memory polymers.
First report on rhinoceros from the late Neogene Qin Basin of Shanxi, China
Authors: Shi Bao‐Zhong , Chen Shao‐Kun , Lu Xiao‐Kang , Deng Tao 
Published: March 2023

AbstractDihoplus is a rhinoceros distributed across East Asia and Europe from the Late Miocene to Pliocene. This study describes a new skull from the Qin Basin in Shanxi Province, China, referred to as Dihoplus ringstroemi, which has long been debated in taxonomic identity. This skull confirms that D. ringstroemi is an independent species and reveals the presence of the upper incisor and variations in the degree of constriction of the two lingual cusps of upper cheek teeth. In addition, the new skull indicates that the Qin Basin has a late Neogene sediment and fauna comparable to that of the Yushe Basin.
Variation in the management of cT1 renal cancer by surgical hospital volume: A nationwide study
Authors: Yildirim H. , Schuurman M. S. , Widdershoven C. V. , Lagerveld B. W. , van den Brink L. , Ruiter A. E. C. , Beerlage H. P. , van Moorselaar R. J. A. , Graafland N. M. , Bex A. , Aben K. K. H. , Zondervan P. J. 
Published: March 2023

AbstractObjectivesTo analyse variation in clinical management of cT1 renal cell carcinoma (RCC) in the Netherlands related to surgical hospital volume (HV).Materials and methodsPatients diagnosed with cT1 RCC during 2014–2020 were identified in the Netherlands Cancer Registry. Patient and tumour characteristics were retrieved. Hospitals performing kidney cancer surgery were categorised by annual HV as low (HV < 25), medium (HV = 25–49) and high (HV > 50). Trends over time in nephron‐sparing strategies for cT1a and cT1b were evaluated. Patient, tumour and treatment characteristics of (partial) nephrectomies were compared by HV. Variation in applied treatment was studied by HV.ResultsBetween 2014 and 2020, 10 964 patients were diagnosed with cT1 RCC. Over time, a clear increase in nephron‐sparing management was observed. The majority of cT1a underwent a partial nephrectomy (PN), although less PNs were applied over time (from 48% in 2014 to 41% in 2020). Active surveillance (AS) was increasingly applied (from 18% to 32%). For cT1a, 85% received nephron‐sparing management in all HV categories, either with AS, PN or focal therapy (FT). For T1b, radical nephrectomy (RN) remained the most common treatment (from 57% to 50%). Patients in high‐volume hospitals underwent more often PN (35%) for T1b compared with medium HV (28%) and low HV (19%).ConclusionHV is related to variation in the management of cT1 RCC in the Netherlands. The EAU guidelines have recommended PN as preferred treatment for cT1 RCC. In most patients with cT1a, nephron‐sparing management was applied in all HV categories, although differences in applied strategy were found and PN was more frequently used in high HV. For T1b, high HV was associated with less appliance of RN, whereas PN was increasingly used. Therefore, closer guideline adherence was found in high‐volume hospitals.
An overview of CYP27B1 enzyme mutation and management: A case report and review of the literature
Authors: Zamanfar Daniel , Ghazaiean Mobin 
Published: March 2023

AbstractVitamin D‐dependent rickets type 1 (VDDRIA) is an autosomal recessive disorder caused by mutations in the Cytochrome P450 Family 27 Subfamily B Member 1 (CYP27B1) gene, which encodes for the enzyme 1 alpha‐hydroxylase. We report a known case of VDDRIA with hypotonia, growth and developmental disorders and discuss about the mutation and its management.
Familial homozygous hypercholesterolemia with arcus cornea and xanthomas: A rare but serious entity
Authors: Chamli Amal , Zaouak Anissa , Frioui Refka , Fenniche Samy , Hammami Houda 
Published: March 2023

AbstractFamilial hypercholesterolemia (FH) is a rare but life‐threatening disorder. Skin manifestations can be its only manifestation. We present a case of a fifteen‐year‐old female child, with multiple eruptive xanthomas, xanthomas anarcus, and a deranged lipid profile consistent with FH. The presence of this manifestation especially in the younger age group should draw attention to hypercholesterolemia. A timely diagnosis is fundamental to prevent serious complications and for early treatment.
A case of glial fibrillary acidotic protein (GFAP) meningoencephalitis with rheumatoid arthritis
Authors: Salari Mehri , Etemadifar Masoud , Soleymani Reyhaneh , Murgai Aditya Ashok , Rashedi Ronak 
Published: March 2023

AbstractAutoimmune glial fibrillary acidic protein (GFAP) astrocytopathy is an inflammatory disease of the central nervous system (CNS), which affects various regions in the CNS, presenting by variable clinical manifestations. Meningoencephalitis is the most common clinical presentation and association with autoimmune disorders has been reported in about 20% of these patients. Diagnosis is confirmed by the presence of CSF or serum immunoglobulin‐G (IgG) against GFAP. The reported case is a 53‐year‐old woman with the history of long‐standing rheumatoid arthritis who first presented with acute‐onset dizziness and gait disturbance, periventricular linear and radial enhancement pattern on MRI, and normal CSF analysis, successfully treated with an increase in the dose of oral steroids. After a year she had a subacute‐onset, moderate to severe holocephalic headache, normal neurologic examination and CSF analysis, and bilateral diffuse, pachymeningeal, and leptomeningeal enhancement on MRI. According to her Brain MRI imaging with relapsing remitting course steroid responsive ataxia and aseptic meningitis, her serum was tested for GFAP IgG antibodies which was positive. The reported patient is the first in the literature reported pachymeningitis in GFAP astrocytopathy. This case highlights the co‐occurrence of rheumatoid arthritis with GFAP‐associated astrocytopathy, and expands on the previously reported cases with similar association. This might also suggest a common immune pathogenesis.
Prolonged delirium caused by lithium poisoning in an endometrial cancer patient at advanced stage: A case report
Authors: Natsuyama Tomoya , Okamoto Naomichi , Akaji Haruka , Hoshino Kaori , Ikenouchi Atsuko , Yoshimura Reiji 
Published: March 2023

AbstractA patient with schizoaffective disorder and receiving long‐term treatment with lithium developed prolonged delirium. She had recently been diagnosed with stage IVB endometrial cancer and presented a deteriorating general condition. Toxic levels of lithium were measured in serum. After hemodialysis, lithium levels gradually decreased and the symptoms disappeared completely.