bluuebunny/crossref_metadata_2025_split huggingface dataset:
The free chimeric medial sural artery perforator flap for individualised and three‐dimensional reconstruction of complex soft‐tissue defects in extremities
Authors: Sui Xinlei , Khan Umar Zeb , Qing Liming , Yu Fang , Wu Panfeng , Tang Juyu 
Published: April 2023

AbstractTrauma or lesion resection often causes complex wounds with deep soft tissue defects in extremities. Simply covering with a skin flap will leave a deep dead space resulting in infection, non‐healing wounds, and poor long‐term outcomes. Thus, effectively reconstructing complex wounds with dead space leaves a clinical challenge. This manuscript presents our experience using chimeric medial sural artery perforator (cMSAP) flap, to reconstruct complex soft tissue defects of the extremities, thereby exploring broader analysis and indications for future reference. Between March 2016 and May 11, 2022, patients (8 males and 3 females) with a mean age of 41 years (range from 26 to 55 years) underwent reconstructive surgery with the cMSAP flap. The cMSAP flap consists of an MSAP skin paddle and a medial sural muscle paddle. The size of the MSAP skin paddle ranged between 9 × 5 cm and 20 × 6 cm, and the size of the medial sural muscle paddle ranged between 2 × 2 cm and 14 × 4 cm. Primary closure of the donor site was achieved in all cases. Of the 11 patients, the cMSAP flap survived in 10 cases. The vascular compromise occurred in one special case and was treated with surgical procedures. The mean follow‐up duration was 16.5 months (range of 5–25 months). Most patients present satisfactory cosmetic and functional results. The free cMSAP flap is a good option for reconstructing complex soft tissue defects with deep dead space in extremities. The skin flap can cover the skin defect, and the muscle flap can fill the dead space against infection. In addition, three types of cMSAP flaps can be used in a broader range of complex wounds. This procedure can achieve an individualised and three‐dimensional reconstruction of the defects and minimise the donor site morbidities.
Single‐step SNPBLUP evaluation in six German beef cattle breeds
Authors: Adekale Damilola , Alkhoder Hatem , Liu Zengting , Segelke Dierck , Tetens Jens 
Published: April 2023

AbstractThe implementation of genomic selection for six German beef cattle populations was evaluated. Although the multiple‐step implementation of genomic selection is the status quo in most national dairy cattle evaluations, the breeding structure of German beef cattle, coupled with the shortcoming and complexity of the multiple‐step method, makes single step a more attractive option to implement genomic selection in German beef cattle populations. Our objective was to develop a national beef cattle single‐step genomic evaluation in five economically important traits in six German beef cattle populations and investigate its impact on the accuracy and bias of genomic evaluations relative to the current pedigree‐based evaluation. Across the six breeds in our study, 461,929 phenotyped and 14,321 genotyped animals were evaluated with a multi‐trait single‐step model. To validate the single‐step model, phenotype data in the last 2 years were removed in a forward validation study. For the conventional and single‐step approaches, the genomic estimated breeding values of validation animals and other animals were compared between the truncated and the full evaluations. The correlation of the GEBVs between the full and truncated evaluations in the validation animals was slightly higher in the single‐step evaluation. The regression of the full GEBVs on truncated GEBVs was close to the optimal value of 1 for both the pedigree‐based and the single‐step evaluations. The SNP effect estimates from the truncated evaluation were highly correlated with those from the full evaluation, with values ranging from 0.79 to 0.94. The correlation of the SNP effect was influenced by the number of genotyped animals shared between the full and truncated evaluations. The regression coefficients of the SNP effect of the full evaluation on the truncated evaluation were all close to the expected value of 1, indicating unbiased estimates of the SNP markers for the production traits. The Manhattan plot of the SNP effect estimates identified chromosomal regions harbouring major genes for muscling and body weight in breeds of French origin. Based on the regression intercept and slope of the GEBVs of validation animals, the single‐step evaluation was neither inflated nor deflated across the six breeds. Overall, the single‐step model resulted in a more accurate and stable evaluation. However, due to the small number of genotyped individuals, the single‐step method only provided slightly better results when compared to the pedigree‐based method.
Insight of electrocardiographic and electrophysiological parameters on the left ventricular function in patients with ventricular arrhythmia from left ventricular summit
Authors: Kuo Ming‐Jen , Lin Chin‐Yu , Lin Yenn‐Jiang , Chang Shih‐Lin , Lo Li‐Wei , Hu Yu‐Feng , Chung Fa‐Po , Tuan Ta‐Chuan , Chao Tze‐Fan , Liao Jo‐Nan , Chang Ting‐Yung , Kuo Ling , Wu Cheng‐I , Liu Chih‐Min , Liu Shin‐Huei , Chen Shih‐Ann 
Published: April 2023

AbstractIntroductionVentricular arrhythmia (VA) commonly originate from the left ventricular summit (LVS) and results in left ventricular (LV) dysfunction in some patients; however, factors related to LV cardiomyopathy have not been well elucidated. Therefore, this study aimed to investigate the risk factors for LV cardiomyopathy and the outcomes of patients with LVS VA.MethodsBetween 2013 and 2018, a total of 139 patients (60.7% men; mean age 53.2 ± 13.9 years old) underwent catheter ablation for LVS VA in two centers. Detailed patient demographics, electrocardiograms, electrophysiological characteristics, and clinical outcomes were analyzed. LV cardiomyopathy was defined as left ventricular ejection fraction (LVEF) <50%.ResultsAcute procedural success was achieved in 92.8% of patients. There were 40 patients (28.8%) with LV cardiomyopathy, and the mean LVEF improved from 37.5 ± 9.3% to 48.5 ± 10.2% after ablation (p < .001). After multivariate analysis, the independent factors of LV dysfunction were wider QRS duration (QRSd) of the VA (odds ratio [OR] 1.02; 95% confidence interval [CI]: 1.00–1.04; p = .046) and the absolute earliest activation time discrepancy (AEAD) between epicardium and endocardium (OR 1.05; 95% CI: 1.00–1.09; p = .048). After ablation, the LV function was completely recovered in 20 patients (50%). The factors for LV dysfunction without recovery included wider premature ventricular complex (PVC) QRSd (OR 1.09; 95% CI: 1.02–1.17; p = .012) and poorer LVEF (OR 0.85; 95% CI: 0.74–0.97; p = .020).ConclusionIn patients with VA from the LVS, PVC QRSd and AEAD are factors associated with deteriorating LV systolic function. Catheter ablation can reverse LV remodeling. Narrower QRSd and better LVEF are associated with better recovery of LV function after ablation.
The role of trigger factors in the occurrence of appropriate ICD shocks and their clinical and prognostic implications
Authors: Lampropoulou Eleni , Kouraki Kleopatra , Strauss Margit , Mohammad Owais , Zahn Ralf , Kleemann Thomas 
Published: April 2023

AbstractBackgroundThe role of triggers in the occurrence of appropriate implantable cardioverter‐defibrillator (ICD) shocks due to ventricular tachyarrhythmias is not well known. The aim of the study was to assess the prevalence of trigger factors in appropriate ICD shocks and to analyze their prognostic impact on clinical outcome.MethodsA total of 710 consecutive patients of a prospective single‐center ICD‐registry who received a first appropriate ICD shock between 2000 and 9/2021 were analyzed.ResultsIn 35% of ICD patients with first ICD shock, at least one of the following triggers was found: Ischemia (22%), Compliance (9%), Decompensation (38%), Stress (12%), Technical (5%), Electrolyte/endocrinological disorder (22%) and Medication side effects (4%). The trigger factors can be summarized under the acronym ICD‐STEMi. The prospective application of the ICD‐STEMi scheme increased the rate of identified triggers from 32% to 56% (p < .001). Patients with triggered first ICD shock had an increased 5‐year mortality rate (50% vs. 38%, p < .001). Patients with triggers did not show different mortality outcomes or recurrent ICD shocks whether they received arrhythmia therapy or not.ConclusionsThe evaluation of trigger factors after the occurrence of ICD shocks is mandatory and can be systematically evaluated using the acronym ICD‐STEMi. Systematic evaluation of triggers using the ICD‐STEMi scheme can identify triggers in about half of ICD patients with first appropriate ICD shock. Patients with triggered ICD shock have a 12% higher 5‐year mortality rate.
Effectiveness of home‐based cardiac telerehabilitation in patients with heart failure: A systematic review and meta‐analysis of randomised controlled trials
Authors: Gao Yan , Wang Nan , Zhang Lixin , Liu Naiquan 
Published: April 2023

AbstractAims and ObjectivesTo evaluate the effectiveness of home‐based cardiac telerehabilitation in patients with heart failure.DesignThis systematic review and meta‐analysis of randomised controlled trials were designed and reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines.MethodsTwo researchers independently screened eligible studies. The Cochrane Handbook for Systematic Reviews of Interventions was used to assess the risk of bias within the included studies. A fixed‐ or random‐effects meta‐analysis model was used to determine the mean difference, based on the results of the heterogeneity test.Data sourcesA librarian‐designed search of the Cochrane Library, PubMed, Web of Science, EMBASE, CINAHL, CBM, CNKI and Wanfang databases was conducted to identify studies in English or Chinese on randomised controlled trials up to 15 August 2022.ResultsA total of 2291 studies were screened. The meta‐analysis included data from 16 studies representing 4557 participants. The results indicated that home‐based cardiac telerehabilitation could improve heart rate, VO2 peak, 6‐minute walk distance, quality of life and reduce readmission rates. No significant differences were observed in the left ventricular ejection fraction percentages between the home‐based cardiac telerehabilitation and usual care groups. Compared with centre‐based cardiac rehabilitation, home‐based cardiac telerehabilitation showed no significant improvement in outcome indicators.ConclusionPatients with heart failure benefit from home‐based cardiac telerehabilitation intervention. With the rapid development of information and communication technology, home‐based cardiac telerehabilitation has great potential and may be used as an adjunct or substitute for centre‐based cardiac rehabilitation.ImpactThis systematic review and meta‐analysis found that patients with heart failure would benefit from home‐based cardiac telerehabilitation intervention in terms of cardiac function, functional capacity, quality‐of‐life management and readmission rate. Future clinical interventions should consider home‐based cardiac telerehabilitation as an alternative to conventional cardiac rehabilitation in patients with heart failure to improve their quality of life.No Patient or Public Contribution:Our paper is a systematic review and meta‐analysis, and such details do not apply to our work.
The effects of weight change from childhood to adulthood on depression and anxiety risk in adulthood: A systematic review
Authors: Gallagher Claire , Waidyatillake Nilakshi , Pirkis Jane , Lambert Katrina , Cassim Raisa , Dharmage Shyamali , Erbas Bircan 
Published: April 2023

SummaryThis review aimed to evaluate the effects of weight change from childhood to adulthood on depression and/or anxiety risk in adulthood. We systematically searched MEDLINE, PsychINFO, Embase, Cumulative Index to Nursing and Allied Health Literature, and Scopus for longitudinal studies assessing changes in weight status between childhood (≤18 years) and adulthood (≥19 years) in association with outcomes of depression and/or anxiety in adulthood. Study quality was assessed using a modified version of the Newcastle‐Ottawa Scale, and data were narratively synthesized. Seventeen articles met our inclusion criteria: 13 evaluated outcomes of depression, one evaluated outcomes of anxiety, and five evaluated composite measures of depression and anxiety. Evidence was most consistent regarding outcomes of depression, with most finding that persistent and/or increasing adiposity from childhood to adulthood is associated with an increased risk of depression, particularly in women. However, heterogeneity and limitations in the evidence preclude definitive conclusions and inconsistent findings were reported in the few studies that assessed anxiety and composite outcomes. Overall, it appears that early intervention to both prevent or resolve excess weight may aid in reducing the burden of depression, along with mental health support targeting adolescents with persistent and/or increasing adiposity. However, further high‐quality research is needed to address the methodological limitations discussed.
Comparative evaluation of nasolabial appearance of unilateral cleft lip and palate patients by professional, patient and layperson using 2 aesthetic scoring systems: A cross sectional study
Authors: Duggal Isha , Talwar Aditya , Duggal Ritu , Chaudhari Prabhat Kumar , Samrit Vilas 
Published: April 2023

AbstractObjectiveTo compare the perspective of healthcare providers (orthodontists), cleft patients and laypersons in judging nasolabial aesthetics in patients with complete unilateral cleft lip, with or without cleft palate (UCL ± P) using 2 scoring systems.DesignThis cross‐sectional study was conducted in a tertiary care government hospital.PatientsPhotographic records of 100 patients with complete UCL ± P from the age group of 5‐18 years (mean age‐12.2 ± 3.93 years) were included in this study.MethodPhotographic records of 100 patients with complete UCL ± P from the age group of 5‐18 years were included. A panel of 3 orthodontists, 3 laypersons and 3 cleft patients rated nasolabial aesthetics using 2 scoring systems i.e. Asher‐McDade index (AMAI) and Cleft Aesthetic Rating Scale (CARS). Spearman's split‐half reliability, Intra‐class correlation coefficient and Cronbach's alpha were computed to measure internal consistency and reliability. Inter‐panel agreement between pair of groups was determined by means of Spearman correlation coefficient.ResultsEstimated reliability of CARS for 3 raters in each panel was in moderate agreement for orthodontists and cleft patients (0.849 and 0.810). Good repeatability and agreement were recorded with moderate to high intra‐panel reliability for all parameters of both AMAI and CARS. Overall inter‐panel agreement was moderate for both AMAI and CARS. Pair‐wise inter‐panel agreement showed a moderately positive correlation in both scales (AMAI and CARS) by cleft patients and professionals.ConclusionCARS index can be reliably used for assessment of nasolabial aesthetics by cleft patients, professionals and lay persons on 2D facial photographs. Patients were more critical than clinicians and laypersons using both indices (CARS and AMAI) as they are more self‐aware and conscious. Thus, a clear communication between clinician and patient regarding expectations, perception and satisfaction with surgical results is strongly recommended.
Systematic use of magnetic double J stent in pediatric kidney transplantation: A single‐center experience
Authors: Spagnoletti Gionata , Larghi Laureiro Zoe , Marincola Giuseppe , Guzzo Isabella , Dello Strologo Luca , Spada Marco 
Published: April 2023

AbstractBackgroundThe intraoperative insertion of a double J stent (DJS) is known to reduce urological complications and is broadly accepted in kidney transplant (KTx) patients. The magnetic ureteral DJS (mDJS) represents a valid alternative device as it can be removed without cystoscopy, using a transurethral magnet. This is of particular importance in the pediatrics, allowing us to avoid cystoscopy requiring general anesthesia (GA) in this population. To date, few data are available on the systematic use of mDJS in pediatric patients undergoing KTx.MethodsWe report a retrospective analysis of 32 consecutive pediatric KTx at our center from July 2020 to December 2021.ResultsUreteral stents remained in place for a median of 35 days (range: 12–76). Non‐surgical magnetic removal of the mDJS was attempted in all cases without complications. In most cases (69%), the removal procedure was performed in an outpatient clinic. In 10 cases, the mDJS was removed in the operating room under sedation before removal of the abdominal Tenckhoff catheter. All patients were clinically followed (range: 3–15 months).ConclusionsWe confirm the safety and feasibility of systematic use of mDJS in the setting of pediatric KTx. The systematic use of this device contributes to reduce the need for GA and the rate of hospital admission.
A machine learning approach to deal with ambiguity in the humanitarian decision‐making
Authors: Grass Emilia , Ortmann Janosch , Balcik Burcu , Rei Walter 
Published: April 2023

One of the major challenges for humanitarian organizations in response planning is dealing with the inherent ambiguity and uncertainty in disaster situations. The available information that comes from different sources in postdisaster settings may involve missing elements and inconsistencies, which can hamper effective humanitarian decision‐making. In this paper, we propose a new methodological framework based on graph clustering and stochastic optimization to support humanitarian decision‐makers in analyzing the implications of divergent estimates from multiple data sources on final decisions and efficiently integrating these estimates into decision‐making. To the best of our knowledge, the integration of ambiguous information into decision‐making by combining a cluster machine learning method with stochastic optimization has not been done before. We illustrate the proposed approach on a realistic case study that focuses on locating shelters to serve internally displaced people (IDP) in a conflict setting, specifically, the Syrian civil war. We use the needs assessment data from two different reliable sources to estimate the shelter needs in Idleb, a district of Syria. The analysis of data provided by two assessment sources has indicated a high degree of ambiguity due to inconsistent estimates. We apply the proposed methodology to integrate divergent estimates in making shelter location decisions. The results highlight that our methodology leads to higher satisfaction of demand for shelters than other approaches such as a classical stochastic programming model. Moreover, we show that our solution integrates information coming from both sources more efficiently thereby hedging against the ambiguity more effectively. With the newly proposed methodology, the decision‐maker is able to analyze the degree of ambiguity in the data and the degree of consensus between different data sources to ultimately make better decisions for delivering humanitarian aid.
On the fields of definition of genus‐one covers of P1$\mathbb {P}^1$
Authors: Molyakov Alexander 
Published: April 2023

AbstractIt is known that sometimes, a Belyi pair is not defined over its field of moduli. Instead, it is defined over a finite degree extension of its field of moduli, called a field of definition. We show that given a number , there exists a Belyi pair such that the degree of a field of definition over the field of moduli is greater than . As a by‐product, we obtain a counterexample to the local‐global principle for Belyi pairs.
Cluster structures for the A∞$A_\infty$ singularity
Authors: August Jenny , Cheung Man Wai , Faber Eleonore , Gratz Sira , Schroll Sibylle 
Published: April 2023

AbstractWe study a category of ‐graded maximal Cohen‐Macaulay (MCM) modules over the curve singularity and demonstrate that it has infinite type cluster combinatorics. In particular, we show that this Frobenius category (or a suitable subcategory) is stably equivalent to the infinite type cluster categories of Holm–Jørgensen, Fisher and Paquette–Yıldırım. As a consequence, has cluster tilting subcategories modelled by certain triangulations of the (completed) ‐gon. We use the Frobenius structure to extend this further to consider maximal almost rigid subcategories, and show that these subcategories and their mutations exhibit the combinatorics of the completed ‐gon.
N. A. Bulienkov’s Simplicial-Modular Design As a Basis for Modeling Metal Clusters
Authors: Tytik D. L. 
Published: April 2023

Abstract
The author considers the main principles of Bulienkov’s simplicial-modular design of metal clusters (face-centered cubic (FCC), body-centered cubic (BCC), hexagonal close-packed (HCP) metals). Models of clusters are presented along with algorithms for their construction based on operations of twinning ($$\bar {1}$$, 2, m) to simplices and modules of the corresponding metals.
Beyond Transactional Democracy: A Study of Civic Tech in Canada
Authors: McCord Curtis W. , Becker Christoph 
Published: April 2023

Technologies are increasingly enrolled in projects to involve civilians in the work of policy-making, often under the label of 'civic technology'. But conventional forms of participation through transactions such as voting provide limited opportunities for engagement. In response, some civic tech groups organize around issues of shared concern to explore new forms of democratic technologies. How does their work affect the relationship between publics and public servants?
This paper explores how a Civic Tech Toronto creates a platform for civic engagement through the maintenance of an autonomous community for civic engagement and participation that is casual, social, nonpartisan, experimental, and flexible. Based on two years of action research, including community organizing, interviews, and observations, this paper shows how this grassroots civic tech group creates a civic platform that places a diverse range of participants in contact with the work of public servants, helping to build capacities and relationships that prepare both publics and public servants for the work of participatory democracy.
The case shows that understanding civic tech requires a lens beyond the mere analysis or production of technical artifacts. As a practice for making technologies that is social and participatory, civic tech creates alternative modes of technology development and opportunities for experimentation and learning, and it can reconfigure the roles of democratic participants.