bluuebunny/crossref_metadata_2025_split huggingface dataset:
INPRES NO 14 TAHUN 1967: BENTUK DISKRIMINASI PEMERINTAH ORDE BARU TERHADAP ETNIS TIONGHOA
Authors: Aryani Mima Kharimah 
Published: July 2023

Masa Orde Baru merupakan masa kelam bagi etnis Tionghoa di Indonesia. Kebebasan mereka direnggut oleh pemerintah Orde Baru yang tentunya tindakan ini merupakan bentuk diskriminasi terhadap warga negara. Pemerintah Orde Baru dengan tegas membentuk kebijakan untuk mengatur warga etnis Tionghoa baik dalam menjalankan agama, kepercayaan, serta adat istiadatnya di Indonesia. Salah satu bentuk kebijakannya tertuang pada Instruksi Presiden No. 14 Tahun 1967. Tujuan penulisan artikel ini adalah untuk mengetahui bagaimana Inpres ini mengatur etnis Tionghoa sehingga membentuk masa kelam bagi mereka. Latar belakang masalah dalam artikel ini lebih difokuskan pada pelaksanaan Inpres No. 14 Tahun 1967 di masa Orde Baru serta dampaknya bagi etnis Tionghoa di Indonesia. Pendekatan yang digunakan dalam penulisan artikel ilmiah ini yaitu dengan studi literatur yang berpedoman pada langkah-langkah penelitian sejarah yaitu Heuristik, Kritik Sejarah, Interpretasi, dan Historiografi. Adapun hasil dari penelitian ini adalah tindakan diskriminasi pemerintah meliputi berbagai bidang kehidupan etnis Tionghoa selama kurang lebih 30 tahun lamanya dan ini berdampak besar pada pola hidup mereka di masa-masa sesudahnya.
Readiness Analysis of Politeknik STMI Jakarta Towards Implementation and Certification of ISO 21001:2018
Authors: Ambarwati Laksmi , Rusmiati Emi , Aisyah Siti 
Published: July 2023

Higher education has great demands and responsibilities to ensure their student graduates as highly competent human resources. Thus, effective and efficient management is required for higher education’s business process. To ensure their quality in process and result, compliance with national regulations and standards related to higher education is a must, and quality conformity with international standards is also one of the efforts of higher education institutions to improve their quality and competitiveness. ISO 21001:2018 is one of the international standards and best practice management systems for educational organizations that are widely used by various higher education institutions in the world. Considering Politeknik STMI Jakarta’s vision for resulting competent human resources, and that it is not yet certified by ISO 21001: 2018, this study is conducted to know the extent of readiness of Politeknik STMI Jakarta towards implementation and certification of ISO 21001:2018. The method used is the gap analysis method between conditions existing in Politeknik STMI Jakarta to ISO 21001:2018 standard. The results showed that the level of readiness of Politeknik STMI Jakarta is 88.85% which showed that the implementation of the clause requirements is mostly carried out but not consistently. The conclusion that can be drawn from the research is that Politeknik STMI Jakarta is ready to implement and carry out ISO 21001: 2018 certification.
Genetic Predisposition of Vulnerable Groups to Schizophrenia and Bipolar I via AKAP11 Variant Analysis
Authors: Tillie Peyton , Sidhu Sohila , Hu Vivian , Mohamad Ali , Vollmer Elle 
Published: July 2023

Recent exome sequencing analyses have shown that schizophrenia and
bipolar I disorder, collectively affecting 2% of the population, may
extend from a common genetic origin of the AKAP11 gene. Though
several studies have been put forth to examine the relationship between
the pathogenesis of these mental illnesses and AKAP11 variants, a
model has yet to be created that tests this hypothesis by accounting for
real–world diagnosis frequencies in addition to a genetic framework.
Analogously, no genetic study has been put forth to identify specific
vulnerable groups in the development of either schizophrenia or bipolar
disorder. To provide additional insight into the pathogenesis of these
diseases, we perform ordinal logistic regression on every AKAP11
variant in the SCHEMA and BipEx data sets. Primarily using the CADD
genome annotation, we establish the probability that each variant is
deleterious. We use a chi–square goodness of fit test to demonstrate
that the amino acids coded for by high–risk variants are similar
between schizophrenia and bipolar disorder, suggesting a common
underlying genetic origin. Additionally, a sequence of one–sided
t tests is run to compare the age and sex frequencies of these
high­–risk variants to the frequencies of schizophrenia and bipolar I
diagnoses among the Canadian population. In total, we find that
AKAP11 exhibits a strong correlation with bipolar I disorder and
a moderate correlation with schizophrenia. We also find that males
under 30 and females between 50 and 55 are most vulnerable to
schizophrenia and bipolar I, respectively.
Artificial Sweeteners and Risk of Type 2 Diabetes in the Prospective NutriNet-Santé Cohort
Authors: Debras Charlotte , Deschasaux-Tanguy Mélanie , Chazelas Eloi , Sellem Laury , Druesne-Pecollo Nathalie , Esseddik Younes , Szabo de Edelenyi Fabien , Agaësse Cédric , De Sa Alexandre , Lutchia Rebecca , Julia Chantal , Kesse-Guyot Emmanuelle , Allès Benjamin , Galan Pilar , Hercberg Serge , Huybrechts Inge , Cosson Emmanuel , Tatulashvili Sopio , Srour Bernard , Touvier Mathilde 
Published: July 2023

OBJECTIVETo study the relationships between artificial sweeteners, accounting for all dietary sources (total and by type of artificial sweetener) and risk of type 2 diabetes (T2D), in a large-scale prospective cohort.RESEARCH DESIGN AND METHODSThe analyses included 105,588 participants from the web-based NutriNet-Santé study (France, 2009–2022; mean age 42.5 ± 14.6 years, 79.2% women). Repeated 24-h dietary records, including brands and commercial names of industrial products, merged with qualitative and quantitative food additive composition data, enabled artificial sweetener intakes to be accurately assessed from all dietary sources. Associations between artificial sweeteners (total, aspartame, acesulfame potassium [K], and sucralose) and T2D were investigated using Cox proportional hazard models adjusted for potential confounders, including weight variation during follow-up.RESULTSDuring a median follow-up of 9.1 years (946,650 person-years, 972 incident T2D), compared with nonconsumers, higher consumers of artificial sweeteners (i.e., above the sex-specific medians of 16.4 mg/day in men and 18.5 mg/day in women) had higher risks of developing T2D (hazard ratio [HR] 1.69; 95% CI 1.45–1.97; P-trend &lt;0.001). Positive associations were also observed for individual artificial sweeteners: aspartame (HR 1.63 [95% CI 1.38–1.93], P-trend &lt;0.001), acesulfame-K (HR 1.70 [1.42–2.04], P-trend &lt;0.001), and sucralose (HR 1.34 [1.07–1.69], P-trend = 0.013).CONCLUSIONSPotential for reverse causality cannot be eliminated; however, many sensitivity analyses were computed to limit this and other potential biases. These findings of positive associations between artificial sweetener intakes and increased T2D risk strengthen the evidence that these additives may not be safe sugar alternatives. This study provides important insights in the context of on-going reevaluation of artificial sweeteners by health authorities worldwide.
Lean production in the decrease time expenses at publication of a scientific journal
Authors: Bolshakov D. Yu. 
Published: July 2023

The results of work on the optimization of processes in the editorial office of a scientific journal (reviewing, working out the text of articles by the authors according to the comments of reviewers, literary editing, layout, coordination with the authors) are presented. During the work, non-production losses were analyzed and reduced.The aim of the project was to optimally use the available resources to reduce time costs in the production of the scientific journal.The task of the project was to analyze the sequence, time and distribution law of the editorial and publishing processes of the scientific journal, and on their basis to develop recommendations for eliminating losses and implement their activities of the editorial staff of the scientific journal.As a result of the project: several times reduced losses when reviewing manuscripts; the average time for reviewing articles is maintained with a significant increase in the flow of incoming articles over a short period of time; the average time of delay in the release of magazines has been reduced. In the course of the work, it was revealed that lean production methods (lean methods) are also applicable to complex formalized processes that, at their core, clearly do not create added value and do not deal with physical production, and process optimization significantly affects customer satisfaction. The results of the Gantt diagram before and after of lean productions had been presented.
Nurses' Self-Compassion and Professional Quality of Life During COVID-19 Pandemic: A cross-sectional study
Authors: Juniarta Juniarta , Gea Idem Suarni , Lalenoh Wahyu Shisilia , Tatontos Yunira Elsa Vinolita , Barus Novita Susilawati 
Published: July 2023

Background: Self-compassion enables nurses to understand, know, and love themselves when faced with challenges, specifically during the COVID-19 pandemic. It will decrease compassion fatigue and raises compassion satisfaction.
Purpose: This study aimed to test how nurses’ self-compassion related to their professional quality of life (compassion satisfaction, burnout, and secondary traumatic stress) during the COVID-19 pandemic in Indonesia.
Methods: This was a quantitative correlational study which recruited 234 nurses from all over Indonesia using convenience sampling technique. To collect data, an online survey was administered. Descriptive statistics and the Spearman rank test were used to analyze the collected data.
Results: Self-compassion and compassion satisfaction have been found to have significant relationships (p=0.718), likewise self-compassion and burnout (p=0.726), and self-compassion and secondary traumatic stress (p=0.516).
Conclusions: Self-compassion increases compassion satisfaction. When nurses care for themselves, compassion fatigue (burnout and secondary traumatic stress) will be reduced, and vice versa. Self-awareness is required for nurses to cultivate self-compassion by focusing on and accepting each live event without regret.
Protective effects of N-acetyl-l-cysteine against penconazole-triggered hepatorenal toxicity in adult rats
Authors: Morgan Ashraf M. , Ogaly Hanan A. , Kamel Shaimaa , Rashad Maha M. , Hassanen Eman I. , Ibrahim Marwa A. , Galal Mona K. , Yassin Aya M. , Dulmani Sharah A. Al , Al-Zahrani Fatimah A.M. , Hussien Ahmed M. 
Published: July 2023

Abstract

Introduction
Penconazole (PEN) is a widely applied triazole fungicide. This study sought to define the efficacy of N-acetyl-l-cysteine (NAC) in mitigating PEN-triggered hepatorenal toxicity in rats.

Material and Methods
Twenty-eight adult male albino Wistar rats were assigned to four groups: a normal control (NC), a PEN group, a NAC group and a PEN+NAC group. Administration of PEN (50 mg/kg body weight (b.w.) every 2 days) and NAC (150 mg/kg b.w., daily) took place via oral gavage for 10 days.

Results
Effective amelioration by NAC of PEN-induced liver and kidney dysfunction was indicated by a significant reduction in the circulating liver and kidney markers (aspartate aminotransferase, alanine aminotransferase, urea and creatinine). Attenuation of PEN-induced oxidative stress and lipid peroxidation in liver and kidney tissues was evident in a significant reduction in malondialdehyde and enhanced total antioxidant capacity. Moreover, NAC significantly reduced the histopathological alterations and the expression of tumour necrosis factor α in liver and kidney tissue. Furthermore, NAC maintained the messenger RNA levels of nuclear factor erythroid 2-related factor 2 (Nrf2), haem oxygenase 1, and Kelch-like erythroid cell-derived protein 1 and prevented nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) protein upregulation caused by PEN.

Conclusion
N-acetyl-1-cysteine protected against PEN-induced hepatorenal oxidative damage and inflammatory response via activation of Nrf2 and inhibition of NF-κB pathways.
Inter-laboratory validation of liquid chromatography–tandem mass spectrometry multi-mycotoxin determination in animal feed – method transfer from the reference laboratory to regional laboratories
Authors: Jedziniak Piotr , Panasiuk Łukasz , Pietruszka Katarzyna , Kolano Krzysztof , Zbytniewski Radosław 
Published: July 2023

Abstract

Introduction
The results are presented of the inter-laboratory validation of a liquid chromatography–tandem mass spectrometry method for the determination of eight mycotoxins (aflatoxin B1, deoxynivalenol, fumonisin B1, fumonisin B2, ochratoxin A, toxin T-2, toxin HT-2 and zearalenone) in animal feeds.

Material and Methods
This study was an essential part of the method’s transfer from the National Reference Laboratory to six regional laboratories in Poland working in the official survey of mycotoxins in feed. The laboratories received a batch of standard solutions, blank samples and quality control materials on which to perform analysis with one procedure and different liquid chromatography–tandem mass spectrometry conditions.

Results
The validation results show good precision (reproducibility coefficient of variation 3.7–20.5%) and accuracy of the method (recovery 89–120% and trueness 94–103%) and sufficient skills of the laboratory personnel.

Conclusion
The study is an example of the successful transfer of the method among laboratories.
Influence of composition of curing agent and sand ratio of engineering excavated soil on mechanical properties of fluidized solidified soil
Authors: Liu Shuai , Zhan Jinsheng , Wang Xiaoli 
Published: July 2023

Abstract
With the continuous expansion of the urban scale, the development of engineering construction has been accelerated. In this process, excavated engineered soils produced in the construction process are facing the problem of difficult treatment. In this work, the influence of the composition ratio of different curing agents on the strength of fluidized solidified soil was studied. It was found that when the proportion of fly ash and quicklime in the curing agent was 1:1, and the percentage of the curing agent in the soil was 15%, the 28 days unconfined compressive strength of fluidized solidified soil reached the maximum value. When the composition and content of the curing agent and the slump of the fluidized solidified soil remained unchanged, the strength and water stability of the fluidized solidified soil increased with the increase of the sand ratio of the excavated engineered soil. X-ray powder diffraction (XRD) and scanning electron microscopy (SEM) showed that with the increase of sand in the soil ratio, more needle-like ettringite crystals were produced in the fluidized solidified soil, which were more compact, had fewer voids, and had higher overall compactness. The carbon emissions of the prepared fluidized solidified soil and the common backfill materials were calculated, and it proved that the carbon emissions of the fluidized solidified soil were the lowest. Therefore, this work offers a new method for resource utilization of excavated soil and provides a carbon emission reference for green low-carbon building materials. Finally, it was recommended to choose engineered excavation soil with high sand content to obtain higher performance from fluidized solidified soil.
PENDETEKSIAN JUMLAH PENUMPANG YANG MASUK BERDASARKAN CCTV PADA PINTU BUS DENGAN METODE YOLO
Authors: Marcellino Vincent , Christanti Mawardi Viny , Jaya Perdana Novario 
Published: July 2023

Salah satu cara untuk mengurangi kemacetan pada kota besar adalah dengan mengubah pola pikir masyarakat untuk lebih menggunakan kendaraan umum, kendaraan umum bus merupakan salah bentuk dari kendaraan umum. Namun kelebihan penumpang pada kendaraan umum merupakan permasalahan yang dapat ditemukan. Perancangan pendeteksian jumlah penumpang ini bertujuan untuk membantu melakukan perhitungan jumlah penumpang dari kendaraan umum menggunakan kamera, guna mendeteksi jumlah penumpang dalam kendaraan umum. Perancangan ini menggunakan algoritma YOLO (You Only Look Once), algoritma ini digunakan karena memiliki performa pendeteksian yang cepat pada skenario pendeteksian secara real-time. Perancangan ini menggunakan data berupa gambar yang telah dipecah dari video untuk kemudian digunakan sebagai data latih, data uji, dan data validasi. Setelah melakukan proses pengujian dengan 50 data video untuk pintu masuk dan pintu keluar, hasil yang didapatkan berupa 82% untuk tingkat akurasi perhitungan penumpang pada data video pintu masuk dan 72% untuk tingkat akurasi perhitungan penumpang pada data video pintu keluar.
PERANCANGAN SISTEM INFORMASI BERBASIS WEB UNTUK PROSES PENGELOLAAN PAKAN PADA CV SEHATI FARM
Authors: Yovita Evangelyn , Rusdi Zyad 
Published: July 2023

Recently, technology developments have had a great impact on the company's business processes. To support the company's business processes, a web-based information system was created for the feed management process. The application creation method uses the agile method, where there are several stages that will be passed, namely planning, analysis, design, implementation, and maintenance. The system development process uses UML (Unified Modeling Language). For the creation of the application used Php and the Bootstrap framework. The application created is divided into 3 users, namely Admin who can access the entire application menu, Head of warehouse who can input the feed management process and owner who can see the results of reports.
PERANCANGAN SISTEM INFORMASI MANAJEMEN EKSTRAKURIKULER BERBASIS WEB PADA SMA X JAKARTA
Authors: Livia Samanta 
Published: July 2023

Extracurriculars in education are intended to answer the demands of student’s needs. By participating in extracurricular activities, students will be assisted with creative learning patterns that can increase creativity. In fact, in limited school hours there are many activities that cannot always be carried out, so extracurriculars are created where the implementation is carried out outside school hours to accommodate students in meeting their needs, interests and talents. The management of the extracurricular information system at SMA X has problems, where students sometimes do not get information such as schedules, grades, extracurricular activities and extracurricular registration is done by submitting registration forms where this activity results in file accumulation, which is of course very ineffective nowadays.

From the existing problems, the researchers created a web-based extracurricular management information system with HTML, PHP, Bootstrap and database programming languages. This system was tested using the usability testing method which was directly tested on extracurricular members. The method used in the development of the system is the waterfall method. This system is expected to facilitate the extracurricular information management process and can provide extensive information about the extracurricular activities themselves, so that the information provided is not broken down and integrated in one system and can be useful for students, teachers and schools.
AVALIAÇÃO TOXICOLÓGICA E DETERMINAÇÃO DA DL 50 DO EXTRATO BRUTO DE LUFFA OPERCULATA COGN. (CUCURBITACEAE)
Authors: Badin Rebeka Caribé , Manaças Liliane Rosa Alves , De Souza Ivone Antônia 
Published: July 2023

As plantas medicinais têm sido bastante utilizadas para o tratamento de várias enfermidades pelo homem. Numerosos compostos bioativos obtidos de plantas medicinais apresentam atividades antimicrobianas, antivirais, anticancerígenas, anti-inflamatórias, antioxidantes e neuromoduladoras. Entretanto, existe um número crescente de estudos científicos que comprovam a toxicidade de plantas medicinais. O fruto da Luffa operculata Cogn. é utilizado popularmente como purgante, emenogogo, expectorante e rinossinusite. Este trabalho teve como objetivo avaliar a toxicidade aguda e determinar a dose letal 50% (LD50) do extrato bruto etanólico de Luffa operculata Cogn., por via intraperitoneal em camundongos. No experimento foi utilizado camundongos albinos fêmeas Swiss (Mus Muscullus). Os animais foram divididos em grupos (n=6/grupo), e a toxicidade foi avaliada em duas etapas: preliminar e definitiva. As reações comportamentais relacionadas às doses administradas do extrato de Luffa operculata Cogn. foram taquicardia, taquipneia, movimentos estereotipados e circulares e piloereção. Após essa fase, os animais apresentaram reações depressoras envolvendo apneia e prostração. Além disso, os animais apresentaram outros comportamentos como: contorções abdominais, tônus da musculatura abdominal, espasmos e irritação da conjuntiva. O extrato de Luffa operculata Cogn. apresentou uma DL50 de 3,3 mg/Kg de peso corpóreo, sendo considerada muito tóxica. Como essa planta é largamente usada pela população para fins terapêuticos, alertamos quanto a utilização indiscriminada devido ao alto potencial tóxico.
TANGGUNG JAWAB DIREKSI DAN NOTARIS TERHADAP PERSEROAN TERBATAS YANG BELUM BERBADAN HUKUM PERSPEKTIF PRINSIP FIDUCIARY DUTIES
Authors: Taufik Nailatul Fadhila 
Published: July 2023

Rumusan Masalah dalam Penelitian ini adalah Bagaimana tanggung jawab direksi dalam melakukan perbuatan hukum Ketika perseroan terbatas belum menjadi badan hukum berdasarkan perspektif prinsip fiduciary duties? Apakah peran Notaris sebagai Apakah peran Notaris sebagai pembuat Akta Pendirian Perseroan Terbatas dalam menjelaskan kedudukan dan pertanggungjawaban direksi dan para pendiri dalam bertindak atas Perseroan Terbatas? Tipe penelitian ini normatif dengan menggunakan metode pendekatan perundang-undangan, pendekatan konseptual dan pendekatan kasus, dengan menggunakan teori tanggungjawab, teori organ dan teori kewenangan. Kesimpulannya Perseroan Terbatas yang belum berbadan hukum ketika para anggota nya melaksanakan suatu perbuatan hukum maka tanggungjawab dari apa yang di laksanakannya tersebut adalah menjadi tanggung jawab pribadi secara taggung renteng para anggota terhadap perbuatan hukum tersebut, maka perbuatan hukum tersebut menjadi tanggungjawab Perseroan Terbatas Ketika perseroan tersebut telah menjadi Subjek Hukum, yaitu saat Perseroan telah di daftarkan ke Menteri dan menjadi Badan Hukum, dan perbuatan Hukum tersebut telah di setujui oleh semua pemegang saham perseroan dalam Rapat Umum Pemegang Saham.