bluuebunny/crossref_metadata_2025_split huggingface dataset:
Severe anal intraepithelial neoplasia trends and subsequent invasive anal cancer in the United States
Authors: Haas Cameron B , Engels Eric A , Palefsky Joel M , Clarke Megan A , Kreimer Aimée R , Luo Qianlai , Pfeiffer Ruth M , Qiao Baozhen , Pawlish Karen S , Monterosso Analise , Shiels Meredith S 
Published: August 2023

Abstract

Background
Anal intraepithelial neoplasia grade III is a precursor to squamous cell carcinoma of the anus for which rates are nearly 20-fold higher in people with HIV than in the general population in the United States. We describe trends in anal intraepithelial neoplasia grade III diagnosis and risk of squamous cell carcinoma of the anus following anal intraepithelial neoplasia grade III by HIV status and sex.

Methods
We used data from a population-based linkage between cancer and HIV registries in 11 US states; Puerto Rico; and Washington, DC, during 1996-2019. We identified all individuals with a diagnosis of anal intraepithelial neoplasia grade III and determined their HIV status. We estimated the average annual percentage change of anal intraepithelial neoplasia grade III using Poisson regression stratified by HIV status and sex. We estimated the 5-year cumulative incidence of squamous cell carcinoma of the anus following an anal intraepithelial neoplasia grade III diagnosis stratified by sex, HIV status, and prior AIDS diagnosis.

Results
Among people with HIV, average annual percentage changes for anal intraepithelial neoplasia grade III were 15% (95% confidence interval [CI] = 12% to 17%) per year among females and 12% (95% CI = 11% to 14%) among males. Average annual percentage changes for those without HIV were 8% (95% CI = 7% to 8%) for females and 8% (95% CI = 6% to 9%) for males. Among people with HIV, a prior AIDS diagnosis was associated with a 2.7-fold (95% CI = 2.23 to 3.40) and 1.9-fold (95% CI = 1.72 to 2.02) increased risk of anal intraepithelial neoplasia grade III diagnosis for females and males, respectively. Five-year cumulative incidence of squamous cell carcinoma of the anus following anal intraepithelial neoplasia grade III for people with HIV with a prior AIDS diagnosis were 3.4% and 3.7% for females and males, respectively.

Conclusions
Rates of anal intraepithelial neoplasia grade III diagnoses have increased since 1996, particularly for people with HIV, likely influenced by increased screening. A prior AIDS diagnosis was strongly associated with risk of anal intraepithelial neoplasia grade III diagnosis.
Commentary: Actionable Steps for Addressing Pediatric Pain in Rural and Underserved Communities: Disrupting Our Approach to Psychological Science and Care
Authors: Cunningham Natoshia R , Reid Mallet R , Love Sarah C , Connelly Mark A 
Published: August 2023

Abstract
Although chronic pain is one of the most common health issues affecting children, disparities in access to behavioral healthcare limit its proper identification and management. There is a critical need to move beyond traditional care delivery approaches for chronic pain to reach those in communities that have limited access to care. We argue one means of doing so is to leverage our skills and expertise as psychologists to partner with and train professionals who have established relationships with youth in these communities. Drawing from a community-engaged dissemination and implementation science framework and our research implementing pain management strategies in rural and underserved communities, we review actionable strategies for disrupting traditional psychological methods to expand access to care for children with chronic pain.
Sexual growth and destiny beliefs: Longitudinal associations with dyadic coping among couples seeking medically assisted reproduction
Authors: Rossi Meghan A , Péloquin Katherine , Allsop David B , El Amiri Sawsane , Bouzayen Renda , Brassard Audrey , Bergeron Sophie , Rosen Natalie O 
Published: August 2023

AbstractBackgroundMedically assisted reproduction is a vulnerable time for couples’ sexual health. Believing that sexual challenges can be worked through (i.e., sexual growth beliefs) or that these challenges indicate incompatibility (i.e., sexual destiny beliefs) may be related to dyadic coping—the strategies couples use to cope—with the physical and psychological stressors of medically assisted reproduction.AimIn the current study we aimed to examine the longitudinal associations between typical (i.e., average) levels of sexual growth and destiny beliefs and positive and negative facets of dyadic coping and how greater than typical levels of these constructs predicted each other across time.MethodsCouples (n = 219) seeking medically assisted reproduction were recruited for an online longitudinal, dyadic study.OutcomesCouples completed online measures of sexual growth and destiny beliefs and positive and negative dyadic coping at baseline, 6-and 12-months.ResultsRandom intercept cross-lagged panel models demonstrated that at the within-person level, reporting higher sexual growth beliefs at baseline, relative to their average across time points, was associated with lower negative dyadic coping at 6 months. Higher negative dyadic coping at 6 months, relative to their average, was linked to lower sexual growth beliefs at 12-months. When individuals reported higher sexual destiny beliefs at 6-months, relative to their average, they and their partners reported higher negative dyadic coping at 12 -months. At the between-person level, higher overall levels of sexual destiny beliefs were related to higher overall levels of negative dyadic coping. No associations with positive dyadic coping were identified.Clinical ImplicationsCouples may benefit from identifying and reducing unhelpful beliefs about sex and negative dyadic coping.Strengths and LimitationsStrengths of this study include our large, inclusive sample, engagement of community partners, and novel analytical approach to assess change over time. However, following couples in 6-month increments and not using questionnaires specific to medically assisted reproduction may have limited our ability to detect nuanced changes that couples experience during this time.ConclusionLower sexual growth and higher sexual destiny beliefs may promote couples’ engagement in less adaptive coping behaviors as they seek medically assisted reproduction.
Efficient Bayesian automatic calibration of a functional–structural wheat model using an adaptive design and a metamodelling approach
Authors: Blanc Emmanuelle , Enjalbert Jérôme , Flutre Timothée , Barbillon Pierre 
Published: August 2023

AbstractFunctional–structural plant models are increasingly being used by plant scientists to address a wide variety of questions. However, the calibration of these complex models is often challenging, mainly because of their high computational cost, and, as a result, error propagation is usually ignored. Here we applied an automatic method to the calibration of WALTer: a functional–structural wheat model that simulates the plasticity of tillering in response to competition for light. We used a Bayesian calibration method to jointly estimate the values of five parameters and quantify their uncertainty by fitting the model outputs to tillering dynamics data. We made recourse to Gaussian process metamodels in order to alleviate the computational cost of WALTer. These metamodels are built from an adaptive design that consists of successive runs of WALTer chosen by an efficient global optimization algorithm specifically adapted to this particular calibration task. The method presented here performed well on both synthetic and experimental data. It is an efficient approach for the calibration of WALTer and should be of interest for the calibration of other functional–structural plant models.
Challenges of Electron Correlation Microscopy on Amorphous Silicon and Amorphous Germanium
Authors: Radić Dražen , Peterlechner Martin , Spangenberg Katharina , Posselt Matthias , Bracht Hartmut 
Published: August 2023

Abstract
Electron correlation microscopy experiments were conducted on amorphous germanium (a-Ge) and amorphous silicon (a-Si) with the goal to study self-diffusion. For this purpose, a series of tilted dark-field images were acquired during in situ heating of the samples in a transmission electron microscope. These experiments show that the measurements are greatly affected by artefacts. Contamination, crystallization, electron beam-induced sputtering, and macroscopic bending of the samples pose major obstacles to the measurements. Other, more subtle experimental artefacts could occur in addition to these which makes interpretations regarding the structural dynamics nearly impossible. The data were nonetheless evaluated to see if some useful information could be extracted. One such result is that the distribution of the characteristic times τKWW, which were obtained from stretched exponential fits to the intensity autocorrelation data, is spatially heterogeneous. This spatial heterogeneity is assumed to be caused by a potential nonergodicity of the materials, the artefacts or an inhomogeneous amorphous structure. Further data processing shows that the characteristic times τKWW are moreover temperature independent, especially for the a-Ge data. It is concluded that the structural rearrangements over time are primarily electron beam-driven and that diffusive dynamics are too slow to be measured at the chosen, experimentally accessible annealing temperatures.
Cataclysmic Variables from Sloan Digital Sky Survey – V. The search for period bouncers continues
Authors: Inight K , Gänsicke Boris T , Schwope A , Anderson S F , Badenes C , Breedt E , Chandra V , Davies B D R , Gentile Fusillo N P , Green M J , Hermes J J , Huamani I Achaica , Hwang H , Knauff K , Kurpas J , Long K S , Malanushenko V , Morrison S , Quiroz C. I J , Ramos G N Aichele , Roman-Lopes A , Schreiber M R , Standke A , Stütz L , Thorstensen J R , Toloza O , Tovmassian G , Zakamska N L 
Published: August 2023

ABSTRACT
SDSS-V is carrying out a dedicated survey for white dwarfs, single, and in binaries, and we report the analysis of the spectroscopy of 118 cataclysmic variables (CVs) and CV candidates obtained during the final plug plate observations of SDSS. We identify eight new CVs, spectroscopically confirm 53 and refute 11 published CV candidates, and we report 21 new or improved orbital periods. The orbital period distribution of the SDSS-V CVs does not clearly exhibit a period gap. In common with previous studies, the distribution shows that spectroscopically identified CVs have a larger proportion of short-period systems compared to samples identified from photometric variability. Remarkably, despite a systematic search, we find very few period bouncers. We estimate the space density of period bouncers to be $\simeq 0.2\times 10^{-6}\, \mathrm{pc}^{-3}$, i.e. they represent only a few per cent of the total CV population. This suggests that during their final phase of evolution, CVs either destroy the donor, e.g. via a merger, or that they become detached and cease mass transfer.
Sub-second infrared variability from the archetypal accreting neutron star 4U 1728−34
Authors: Vincentelli F M , Casella P , Borghese A , Cavecchi Y , Mastroserio G , Stella L , Altamirano D , Padilla M Armas , Baglio M C , Belloni T M , Casares J , Cúneo V A , Degenaar N , Trigo M Díaz , Fender R , Maccarone T , Malzac J , Sánchez D Mata , Middleton M , Migliari S , Muñoz-Darias T , O’Brien K , Panizo-Espinar G , Sánchez-Sierras J , Russell D M , Uttley P 
Published: August 2023

ABSTRACT
We report on the first simultaneous high-time resolution X-ray and infrared (IR) observations of a neutron star low mass X-ray binary in its hard state. We performed $\approx 2\,$ h of simultaneous observations of 4U 1728−34 using HAWK-I@VLT, XMM–Newton, and NuSTAR. The source displayed significant X-ray and IR variability down to sub-second time-scales. By measuring the cross-correlation function between the IR and X-ray lightcurves, we discovered a significant correlation with an IR lead of $\approx 30 \!-\! 40\,$ ms with respect to the X-rays. We analysed the X-ray energy dependence of the lag, finding a marginal increase towards higher energies. Given the sign of the lag, we interpret this as possible evidence of Comptonization from external seed photons. We discuss the origin of the IR seed photons in terms of cyclo-synchrotron radiation from an extended hot flow. Finally, we also observed the IR counterpart of a type-I X-ray burst, with a delay of $\approx 7.2\,$ s. Although some additional effects may be at play, by assuming that this lag is due to light travel time between the central object and the companion star, we find that 4U 1728−34 must have an orbital period longer than $3\,$ h and an inclination higher than 8○.
An excursion into the core of the cluster lens Abell 1689
Authors: Ghosh Agniva , Adams Dominic , Williams Liliya L R , Liesenborgs Jori , Alavi Anahita , Scarlata Claudia 
Published: August 2023

ABSTRACT
Abell 1689 is a well-studied cluster of galaxies and one of the largest gravitational lens systems ever observed. We have obtained a reconstruction of the cluster Abell 1689 using grale, a free-form lens inversion method that relies exclusively on the multiple image data. Non-inclusion of any data related to cluster member galaxies ensures an unbiased measure of the mass distribution, which is the most notable feature of free-form methods like grale. We used two different sets of multiple image systems from the available strong lensing data – one containing only the secure systems (107 images) and the other containing all available systems, only excluding some very non-secure systems (151 images). For the very well-constrained central ∼100 kpc region of the cluster, we made a detailed comparison of the grale reconstructed lensing mass and stellar mass retrieved by the Spectral Energy Distribution (SED) fitting software fast++. We found a light-unaccompanied mass peak in this region, whose existence, while tentative, is favoured by the distribution of nearby images that are local maxima in the Fermat potential. However, further tests, using different methodologies are needed to confirm the reality of this feature. If it is shown to be real, this light-unaccompanied mass peak is consistent with dark matter self-interaction cross-section σ ≲ 1 cm2 g−1, while being in tension with larger cross-sections.
Constraints on the spectral signatures of superconducting cosmic strings
Authors: Cyr Bryce , Chluba Jens , Acharya Sandeep Kumar 
Published: August 2023

ABSTRACT
If they exist, networks of superconducting cosmic strings are capable of injecting copious amounts of electromagnetic energy into the background over a broad range of frequencies. We study this injection both analytically, as well as numerically using the thermalization code CosmoTherm. With our refined analytic formalism, we update constraints from CMB spectral distortions by following the injection of entropy, as well as energy, on the amplitude of the μ-distortion, leading to a significant improvement in those limits. Furthermore, we utilize the full shape of the distorted spectrum from CosmoTherm to include constraints from non-μ, non-y type distortions. Additionally, we use the outputs for the ionization history and global 21-cm signal to derive and update constraints on string model parameters using measurements from other data sets. Analysis of CMB anisotropies provides the most stringent constraints, though with a slightly modified shape and strength when compared to previous results. Modifications of the reionization history provide new bounds in the high current domain, and we also find that the observations of the low-frequency radio background probe a small region of parameter space not explored by other data sets. We also analyse global 21-cm constraints, and find that the inclusion of soft photon heating plays a crucial role, essentially removing any constraints in the considered parameter domain. Spectral distortion measurements from COBE/FIRAS are covered by other constraints, but our conservative forecast shows that a PIXIE-type satellite would probe important unexplored regions of parameter space.
Hubble Space Telescope imaging of the compact elliptical galaxy M32 reveals a dearth of carbon stars
Authors: Jones O C , Boyer M L , McDonald I , Meixner M , van Loon J Th 
Published: August 2023

ABSTRACT
We present new Hubble Space Telescope Wide-Field Camera 3/infrared medium-band photometry of the compact elliptical galaxy M32, chemically resolving its thermally pulsating asymptotic giant branch stars. We find 2829 M-type stars and 57 C stars. The carbon stars are likely contaminants from M31. If carbon stars are present in M32 they are so in very low numbers. The uncorrected C/M ratio is 0.020 ± 0.003; this drops to less than 0.007 after taking into account contamination from M31. As the mean metallicity of M32 is just below solar, this low ratio of C to M stars is unlikely due to a metallicity ceiling for the formation of carbon stars. Instead, the age of the asymptotic giant branch (AGB) population is likely to be the primary factor. The ratio of AGB to red giant branch stars in M32 is similar to that of the inner disc of M31 which contain stars that formed 1.5–4 Gyr ago. If the M32 population is at the older end of this age then its lack of C-stars may be consistent with a narrow mass range for carbon star formation predicted by some stellar evolution models. Applying our chemical classifications to the dusty variable stars identified with Spitzer, we find that the x-AGB candidates identified with Spitzer are predominately M-type stars. This substantially increases the lower limit to the cumulative dust-production rate in M32 to &gt; 1.20 × 10−5${\rm M}_{\odot } \, {\rm yr}^{-1}$.
A large sample of newly identified carbon-deficient red giants from APOGEE
Authors: Maben Sunayana , Kumar Yerra Bharat , Reddy Bacham E , Campbell Simon W , Zhao Gang 
Published: August 2023

ABSTRACT
Based on the Apache Point Observatory Galactic Evolution Experiment survey we conducted a search for carbon-deficient red giants (CDGs). We found 103 new CDGs, increasing the number in the literature by more than a factor of 3. CDGs are very rare, representing 0.03 per cent of giants. They appear as an extended tail off the normal carbon distribution. We show that they are found in all components of the Galaxy, contrary to previous findings. The location of CDGs in the Hertzsprung–Russell diagram (HRD) shows that they are primarily intermediate-mass stars ($2-4~\rm {M}_{\odot }$). Their extended distribution may indicate that CDGs can also sometimes have $M \lt 2.0~\rm {M}_{\odot }$. We attempted to identify the evolutionary phases of the CDGs using stellar model tracks. We found that the bulk of the CDGs are likely in the subgiant branch or red clump phase, whereas other CDGs may be in the red giant branch or early asymptotic giant branch phases. Degeneracy in the HRD makes exact identification difficult. We examined their C, N, and O compositions and confirmed previous studies showing that the envelope material has undergone extensive hydrogen burning through the CN(O) cycle. The new-CDGs have [C+N+O/Fe] that generally sum to zero, indicating that they started with scaled-solar composition. However, the previously known-CDGs generally have [C+N+O/Fe] &gt; 0.0, indicating that some He-burning products were added to their envelopes. As to the site(s) in which this originally occurred, we do not find a convincing solution.
Understanding the very high energy γ-ray excess in nearby blazars using leptonic model
Authors: Manzoor Aaqib , Sahayanathan Sunder , Shah Zahir , Bhattacharyya Subir , Iqbal Naseer , Malik Zahoor 
Published: August 2023

ABSTRACT
The availability of simultaneous X-ray and very high energy (VHE) observations of blazars helps to identify the plausible radiative contributors to the VHE emission. Under leptonic scenario, the VHE emission from BL Lacs are attributed to the synchrotron self Compton (SSC) emission. However, many BL Lacerate (BL Lacs) have shown significant hardening at VHE after correction for the extragalactic background light (EBL) attenuation. We study the spectral hardening of two nearby BL Lac objects, Mkn 421 and Mkn 501 having most number of simultaneous X-ray and VHE observations available among all the blazars. These BL Lacs are relatively close and the effect of EBL attenuation is relatively minimal/negligible. We study the scatter plot between the X-ray spectral indices and intrinsic VHE indices to identify the plausible origin of the VHE emission. For Mkn 501, the VHE spectral indices are steeper than X-ray spectra, suggesting the scattering process happening at extreme Klein–Nishina regime. On the other hand, for Mkn 421, the VHE spectra is remarkably harder than the X-ray spectra, which suggests an additional emission mechanism other than the SSC process. We show this hard VHE spectrum of Mkn 421 can be explained by considering the inverse Compton (IC) emission from a broken power-law electron distribution with Maxwellian pileup. The possibility of the hadronic contribution at VHE γ-rays is also explored by modelling the hard spectrum under the photomeson process.
Accretion spin-up of the massive component in the neutron star stripping model for short gamma-ray bursts
Authors: Kramarev Nikita , Yudin Andrey 
Published: August 2023

ABSTRACT
In this paper, we use analytical methods to study the last stages of the double neutron star (NS) system evolution. Depending on the initial masses of the components, this evolution can occur either in the framework of the merging scenario or in the NS stripping model. The main new ingredient of this work, compared with previous calculations, is accounting for accretion spin-up of the massive component. This effect leads to a significant decrease in the duration of the stable mass transfer of matter in the stripping mechanism. Within the framework of the Newtonian approximation, we determine the boundary between the merging and stripping scenarios. It is shown that this boundary weakly depends on the total mass of the system and the specific form of the NS equation of state, and is determined mainly by the initial mass ratio of the components. The stripping scenario is realized at M2/M1 ≲ 0.8, so it should make a large contribution to the population of gravitational wave events from NS–NS coalescing binaries that are close to us, and their accompanying short gamma-ray bursts. Nevertheless, the value obtained requires further clarification, taking into account relativistic effects, possible non-conservative mass transfer, etc.