bluuebunny/crossref_metadata_2025_split huggingface dataset:
Virtual Restoration of Ancient Wooden Ships Through Non-rigid 3D Shape Assembly with Ruled-Surface FFD
Authors: Nemoto Takashi , Kobayashi Tetsuya , Kagesawa Masataka , Oishi Takeshi , Kurokochi Hiromasa , Yoshimura Sakuji , Zidan Eissa , Taha Mamdouh 
Published: February 2023

AbstractIn recent years, 3D data has been widely used in archaeology and in the field of conservation and restoration of cultural properties. Virtual restoration, which reconstructs the original state in virtual space, is one of the promising applications utilizing 3D scanning data. Though many studies of virtual restoration have been conducted, it is still challenging to restore the cultural properties that consist of multiple deformable components because it is not feasible to identify the original shape uniquely. As a solution to such a problem, we proposed a non-rigid 3D shape assembly method for virtually restoring wooden ships that are composed of multiple timbers. The deformed timber can be well represented by ruled surface. We proposed a free-form deformation method with a ruled surface and an assembly method to align the deformable components mutually. The method employs a bottom-up approach that does not require reference data for target objects. The proposed framework narrows down the searching space for optimization using the physical constraints of wooden materials, and it can also obtain optimal solutions. We also showed an experimental result, where we virtually restored King Khufu’s first solar boat. The boat was originally constructed by assembling several timbers. The boat was reconstructed as a real object and is currently exhibited at a museum. However, unfortunately, the entire shape of the boat is slightly distorted. We applied the proposed method using archaeological knowledge and then showed the virtual restoration results using the acquired 3D data of the boat’s components.
Isolated relapse of plasma cell leukemia in the central nervous systems: a case report and literature review
Authors: Obo Takafumi , Morita Ken , Sumida Yutaro , Nakazaki-Watadani Kumi , Ikemura Masako , Yasaka Koichiro , Abe Osamu , Takami Hirokazu , Takayanagi Shunsaku , Tanaka Shota , Maki Hiroaki , Masamoto Yosuke , Miwa Akiyoshi , Kurokawa Mineo 
Published: February 2023

AbstractPlasma cell leukemia is a rare yet aggressive form of multiple myeloma characterized by high levels of plasma cells circulating in the peripheral blood. We recently experienced a case of plasma cell leukemia that had been in stringent complete remission for nine years after autologous stem cell transplantations with subsequent courses of lenalidomide maintenance therapy, and then relapsed as an extramedullary plasmacytoma in the central nervous system. Assessment of the bone marrow did not prove proliferation of plasma cells at relapse, but imbalanced elevation of serum levels of free light chains was observed without changes in other clinical biomarkers including immunoglobulin levels. Salvage chemotherapy with isatuximab, pomalidomide, and dexamethasone (IsaPD) was promptly initiated. After two courses of IsaPD, significant remission was achieved and the neuronal symptoms completely resolved. When excessive serum levels of clonotypic free light chains are noted, their significance should be carefully assessed even when plasma cell propagation in the bone marrow is not observed. In such cases, hematologists should search for extramedullary proliferation of plasma cells, including in the immune-privileged central nervous system.
Comparative evaluation of classical and SARIMA-BL time series hybrid models in predicting monthly qualitative parameters of Maroon river
Authors: Ahmadpour Abbas , Mirhashemi Seyed Hassan , Panahi Mehdi 
Published: February 2023

AbstractIn the present study, seasonal autoregressive integrated moving average (SARIMA) time series models, nonlinear BL model, multi-layer perceptron artificial neural network and SARIMA-bilinear hybrid models were employed to predict the quality parameters of total dissolved solids (TDS), sodium adsorption ratio (SAR), electrical conductivity (EC) in the Maroon basin in Khuzestan Province. For fitting the mentioned models, the monthly data were used for the calibration (1970–2000), confirmation (2001–2011) and prediction of the model (2012–2018). The appropriate models of SARIMA, the bilinear BL and SARIMA-BL hybrid models of the rationalized parameters of the above-mentioned quality parameters were selected based on the adequacy tests, such as the Akaike criterion and the independence test of the model residuals (Ljung–Box). To determine the effective input parameters of the network, the partial mutual information (PMI) algorithm was used to model the three monthly EC, TDS, and SAR parameters. Also, for input and output layers linear transfer function and for hidden layer various active functions with the back-propagation learning algorithm were used for modeling and predicting this water quality parameters. Comparison of the models showed the tangible superiority of SARIMA-bilinear hybrid models than the artificial neural network with effective input parameters based on PMI algorithm, SARIMA and bl models in performed prediction of the all three monthly qualitative parameters in all three stages, training-validation-test in Maroon basin.
Sexual functioning in women with functional hypothalamic amenorrhea: exploring the relevance of an underlying polycystic ovary syndrome (PCOS)-phenotype
Authors: Barbagallo F. , Pedrielli G. , Bosoni D. , Tiranini L. , Cucinella L. , Calogero A. E. , Facchinetti F. , Nappi R. E. 
Published: February 2023

Abstract
Purpose
To study sexual function and distress in women with functional hypothalamic amenorrhea (FHA) compared to women with FHA and an underlying polycystic ovary syndrome (PCOS)-phenotype, considering also their psychometric variables. As a secondary aim, we explored the relationship between sexual functioning and hormonal milieu in these women.

Methods
This is a retrospective cross-sectional study conducted on 36 women with typical FHA and 43 women with FHA + PCOS-phenotype. The following validated psychometric questionnaires were administered: Female Sexual Functional Index (FSFI), Female Sexual Distress Scale-Revised (FSDS-R), Body Attitude Test (BAT), Bulimia Investigation Test (BITE), State Anxiety Inventory (STAI), Beck Depression Inventory (BDI), Multidimensional Perfectionism Scale (MPS). Available hormones to formulate FHA diagnosis in the standard routine were considered.

Results
Women with typical FHA reported a significantly lower FSFI total score than women with FHA + PCOS-phenotype (95% CI for median 16–21.3 vs. 21.1–24.1, p = 0.002), whereas the FSDS-R score was similar in the two groups (95% CI for median 6–16 vs. 6–16.3). No statistically significant differences were evident in body attitude, state and trait anxiety, depression, bulimic risk, and perfectionism between the two groups, confirming the two FHA groups were superimposable from a psychometric perspective. State anxiety correlated negatively with the FSFI total score in both typical FHA (rho: − 0.33, p = 0.05) and FHA + PCOS-phenotype (rho: − 0.40, p = 0.009). In the entire study population, a positive correlation was found between luteinizing hormone, androstenedione, and 17ß-estradiol and the total FSFI score (rho: 0.28, p = 0.01; rho: 0.27, p = 0.01, rho: 0.27, p = 0.01, respectively).

Conclusion
Women with FHA showed a very high rate of sexual symptoms as part of their condition, but those with a typical diagnosis displayed a more severe sexual impairment as compared with the FHA + PCOS-phenotype, in spite of a similar psychometric profile. Sexual distress was equally present in both groups (approximately 4 out of 10 women). Further studies should be designed to investigate the potential role of sex hormones, mainly LH-driven androstenedione, in influencing women’s sexual functioning.
Improving the genome and proteome annotations of the marine model diatom Thalassiosira pseudonana using a proteogenomics strategy
Authors: Chen Xiao-Huang , Yang Ming-Kun , Li Yuan-Yuan , Xie Zhang-Xian , Zhang Shu-Feng , Töpel Mats , Amin Shady A. , Lin Lin , Ge Feng , Wang Da-Zhi 
Published: February 2023

AbstractDiatoms are unicellular eukaryotic phytoplankton that account for approximately 20% of global carbon fixation and 40% of marine primary productivity; thus, they are essential for global carbon biogeochemical cycling and climate. The availability of ten diatom genome sequences has facilitated evolutionary, biological and ecological research over the past decade; however, a complimentary map of the diatom proteome with direct measurements of proteins and peptides is still lacking. Here, we present a proteome map of the model marine diatom Thalassiosira pseudonana using high-resolution mass spectrometry combined with a proteogenomic strategy. In-depth proteomic profiling of three different growth phases and three nutrient-deficient samples identified 9526 proteins, accounting for ~ 81% of the predicted protein-coding genes. Proteogenomic analysis identified 1235 novel genes, 975 revised genes, 104 splice variants and 234 single amino acid variants. Furthermore, our quantitative proteomic analysis experimentally demonstrated that a considerable number of novel genes were differentially translated under different nutrient conditions. These findings substantially improve the genome annotation of T. pseudonana and provide insights into new biological functions of diatoms. This relatively comprehensive diatom proteome catalog will complement available diatom genome and transcriptome data to advance biological and ecological research of marine diatoms.
COVID-19 Vaccine Acceptance and Hesitancy Among Health Care Workers in Lebanon
Authors: Youssef Nour J. , Tfaily Nadim K. , Moumneh Mohammad Bahij M. , Boutros Celina F. , Elharake Jad A. , Malik Amyn A. , McFadden SarahAnn M. , Galal Bayan , Yildirim Inci , Khoshnood Kaveh , Omer Saad B. , Memish Ziad A. , Dbaibo Ghassan S. 
Published: February 2023

Abstract
Background
Lebanon endured its worst economic and financial crisis in 2020–2021. To minimize the impact of COVID-19 pandemic, it is important to improve the overall COVID-19 vaccination rate. Given that vaccine hesitancy among health care workers (HCWs) affects the general population’s decision to be vaccinated, our study assessed COVID-19 vaccine acceptance among Lebanon HCWs and identified barriers, demographic differences, and the most trusted sources of COVID-19 information.

Methods
A cross-sectional study was conducted between January and May 2021 among HCWs across nine hospitals, the Orders of Physicians, Nurses, and Pharmacists in Lebanon. Descriptive statistics were performed to evaluate the COVID-19 vaccine acceptance, and univariate and multivariable to identify their predictors.

Results
Among 879 participants, 762 (86.8%) were willing to receive the COVID-19 vaccine, 52 (5.9%) refused, and 64 (7.3%) were undecided. Males (226/254; 88.9%) and those ≥ 55 years (95/100; 95%) had the highest rates of acceptance. Of the 113 who were not willing to receive the vaccine, 54.9% reported that the vaccine was not studied well enough. Participants with a previous SARS-CoV-2 infection and those who did not know if they had a previous infection (p = 0.002) were less likely to accept the vaccine compared to those with no previous infection. The most trusted COVID-19 sources of information were WHO (69.3%) and healthcare providers (68%).

Conclusion
Lebanese HCWs had a relatively high acceptance rate for COVID-19 vaccination compared to other countries. Our findings are important in informing the Lebanese health care authorities to establish programs and interventions to improve vaccine uptake among HCWs and the general population.
Effectiveness of a neonatal intensive care unit–specific antimicrobial stewardship program: A ten-year review
Authors: Assen Katrina H. , Paquette Vanessa , Albert Arianne Y. , Shi Ginger , Srigley Jocelyn A. , Osiovich Horacio , Roberts Ashley D. , Ting Joseph Y. 
Published: February 2023

AbstractObjective:To evaluate the change in consumption of specific antibiotics in a neonatal intensive care unit after the implementation of an antimicrobial stewardship program (ASP).Design:Retrospective cohort study between January 1, 2010, and December 31,2019.Setting:The neonatal intensive care unit at British Columbia Women’s Hospital (Vancouver Canada), a tertiary-care center.Patients:Admitted neonates prescribed antibiotics.Methods:We implemented an ASP with an early implementation phase starting in January 2014 (period 2) and a later phase starting in January 2017 (period 3). Patient demographics were collected, including birth weight, gestational age, history of necrotizing enterocolitis (NEC), and surgical operations from existing databases. Interrupted time-series analysis was used, and comparison of antibiotic days of therapy (DOT) averages were conducted across the preimplementation period (period 1), period 2, and period 3 regarding total patients and subgroups.Results:We identified 4,512 infants. There was a significant decrease in DOT from 472 (95% confidence interval [CI], 431–517) in period 1 to 405 (95% CI, 367–446) in period 2 to 313 (95% CI, 280–350) in period 3. We detected a significant decrease in the use of ampicillin, aminoglycosides, cloxacillin, and linezolid but not in vancomycin or cefotaxime. Subgroup analyses of infants <1,500 g and those without NEC or surgery showed decreases in the use of cloxacillin, aminoglycosides, and linezolid.Conclusions:The implementation of an ASP was associated with a significant decrease in the overall DOT and use of certain antibiotics. This study presents important targets for ongoing ASP work.
Precision diagnostics in children
Authors: Dimitri Paul 
Published: February 2023

AbstractMedical practice is transforming from a reactive to a pro-active and preventive discipline that is underpinned by precision medicine. The advances in technologies in such fields as genomics, proteomics, metabolomics, transcriptomics and artificial intelligence have resulted in a paradigm shift in our understanding of specific diseases in childhood, greatly enhanced by our ability to combine data from changes within cells to the impact of environmental and population changes. Diseases in children have been reclassified as we understand more about their genomic origin and their evolution. Genomic discoveries, additional ‘omics’ data and advances such as optical genome mapping have driven rapid improvements in the precision and speed of diagnoses of diseases in children and are now being incorporated into newborn screening, have improved targeted therapies in childhood and have supported the development of predictive biomarkers to assess therapeutic impact and determine prognosis in congenital and acquired diseases of childhood. New medical device technologies are facilitating data capture at a population level to support higher diagnostic accuracy and tailored therapies in children according to predicted population outcome, and digital ecosystems now tailor therapies and provide support for their specific needs. By capturing biological and environmental data as early as possible in childhood, we can understand factors that predict disease or maintain health and track changes across a more extensive longitudinal path. Data from multiple health and external sources over long-time periods starting from birth or even in thein uteroenvironment will provide further clarity about how to sustain health and prevent or predict disease. In this respect, we will not only use data to diagnose disease, but precision diagnostics will aid the ‘diagnosis of good health’. The principle of ‘start early and change more’ will thus underpin the value of applying a personalised medicine approach early in life.
Theological exegesis and internal trinitarian relations
Authors: Wiarda Timothy 
Published: February 2023

AbstractThe Gospel of Mark includes a series of passages that depict direct interaction between Jesus and God. When viewed in their full literary, historical and canonical contexts, these passages can be seen to address an embryonic trinitarian question concerning the relationship between trusting and worshipping Jesus and trusting and worshipping the one God of Israel. They provide grounds for affirming that mutual love, knowledge and communication have a place in the immanent life of the Trinity, and that these elements bear a meaningful analogical relationship to the love, knowledge and communication that ideally characterise human father–son relations.
A married couple of mathematicians from Vienna remembers Sigmund Freud (1953)
Authors: Siegmund-Schultze Reinhard 
Published: February 2023

ArgumentThe paper is based on a hitherto unexplored document (audiotape of an interview accompanied by a German transcript) from 1953, located in the Freud Papers at the Library of Congress. It contributes to a better understanding of the impact of Freud and of Psychoanalysis on personalities from the exact sciences, here represented by the noted applied mathematicians Richard von Mises and Hilda Geiringer from Vienna. The detailed discussion of the interview sheds some new light on the different roles of Kraus and Freud in the Vienna culture, on the Vienna Jugendkulturbewegung (youth culture movement) during WWI in which Geiringer was involved, on Freud’s and Siegfried Bernfeld’s standing around 1930 among German philosophers and psychologists, and on Wilhelm Fließ’ theory of periodicity, which von Mises—based on his attitude as an applied mathematician—defended against superficial accusations. Finally, new biographical material is provided for von Mises and the remotely related Freud family, and for Geiringer’s and von Mises’ early lives. The interview, which was taken during the Cold War, also allows conclusions as to how politics influenced the memories and views of the participants. Part of the aim of the paper is historical documentation of unknown material (letters by Karl Kraus and Wolfgang Köhler, one book review by Wilhelm Ostwald, a file on Richard Pfennig), including some correction of erroneous information in the literature.
Grass fires and road structure influence plant invasions in a critical wildlife habitat in north-eastern India
Authors: Banerjee Subham , Das Amit , Rahman Masidur , Bhowal Swapnil , Das Dhritiman , John Robert 
Published: February 2023

SummaryOne of the multiple threats to protected areas worldwide, invasive plant species have the potential to decrease biodiversity and ecosystem function. We studied changes in infestation by two widespread invasive plant species – Chromolaena odorata and Mikania micrantha – in India’s Manas National Park, a critical conservation site for threatened flora and fauna. Based on field surveys in 2011 and 2019, we found that C. odorata and M. micrantha were present in most of the sampled plots and had newly invaded over 20% of the plots. However, the abundance of M. micrantha decreased in 45% of the plots while C. odorata increased in >50% of the plots. We used a decision tree-based regression with environmental variables as predictors to generate the distribution, abundance and invasion risk maps of the two species. Among environmental variables, road proximity and fire frequency had the strongest influences, respectively, on C. odorata and M. micrantha. Invaded quadrats exhibited lower native-plant diversity than non-invaded quadrats, and C. odorata specifically had a strong negative association with native-plant community structure. These invasive species have increased their range and abundance, and our predicted invasion risk maps indicate the areas where management intervention is urgently needed.
Trajectories of parental harshness and exposure to community violence differentially predict externalizing and internalizing mental health problems in legal system-involved youth
Authors: Estrada Suzanne , Baskin-Sommers Arielle 
Published: February 2023

AbstractYouth with legal system involvement are especially likely to experience parental harshness (PH) and exposure to community violence (ETV), two common forms of life stress. However, most studies examine these stressors separately or collapse across them in ways that preclude examination of their co-occurrence. Consequently, it is unclear 1) how PH and ETV simultaneously fluctuate across development and 2) how these fluctuations predict future mental health problems in legal system-involved youth. We used group-based multi-trajectory modeling to estimate simultaneous trajectories of PH and ETV in 1027 legal system-involved youth and regression analyses to understand how trajectory membership predicted mental health problems three years later. Four trajectories of co-occurrence were identified (1: Low; 2: Moderate and Decreasing; 3: Moderate PH/High ETV; 4: High PH/Moderate ETV). Compared to the Low trajectory, all trajectories with PH/ETV elevations predicted violent crime and substance problems; trajectory 3 (Moderate PH/High ETV) predicted nonviolent crime and depression/anxiety symptoms; trajectory 4 (High PH/Moderate ETV) predicted depression diagnosis. These results elucidate how PH and ETV typically co-occur across adolescence for legal system-involved youth. They also reveal important commonalities and dissociations among types of mental health problems.
Better, for worse, or both? Testing environmental sensitivity models with parenting at the level of individual families
Authors: Boele Savannah , Bülow Anne , de Haan Amaranta , Denissen Jaap. J. A. , Keijsers Loes 
Published: February 2023

AbstractAccording to environmental sensitivity models, children vary in responsivity to parenting. However, different models propose different patterns, with responsivity to primarily: (1) adverse parenting (adverse sensitive); or (2) supportive parenting (vantage sensitive); or (3) to both (differentially susceptible). This preregistered study tested whether these three responsivity patterns coexist. We used intensive longitudinal data of Dutch adolescents (N = 256, Mage = 14.8, 72% female) who bi-weekly reported on adverse and supportive parenting and their psychological functioning (tmean = 17.7, tmax = 26). Dynamic Structural Equation Models (DSEM) indeed revealed differential parenting effects. As hypothesized, we found that all three responsivity patterns coexisted in our sample: 5% were adverse sensitive, 3% vantage sensitive, and 26% differentially susceptible. No adolescent appeared unsusceptible, however. Instead, we labeled 28% as unperceptive, because they did not perceive any changes in parenting and scored lower on trait environmental sensitivity than others. Furthermore, unexpected patterns emerged, with 37% responding contrary to parenting theories (e.g., decreased psychological functioning after more parental support). Sensitivity analyses with concurrent effects and parent-reported parenting were performed. Overall, findings indicate that theorized responsivity-to-parenting patterns might coexist in the population, and that there are other, previously undetected patterns that go beyond environmental sensitivity models.