bluuebunny/crossref_metadata_2025_split huggingface dataset:
Global and sectoral retinal nerve fiber layer thickness in glaucoma suspects and primary open-angle glaucoma patients attending a tertiary care center in South India
Authors: Sreedharan Sreeniya Amadan , Sudha V. , Nambudiri Sujatha , Thulaseedharan Sinumol Sukumaran 
Published: May 2023

ABSTRACT

Background:
Spectral-domain optical coherence tomography (OCT) can identify the presence of localized glaucomatous structural damage. The peripapillary retinal nerve fiber layer (RNFL) thickness is a popular OCT parameter used for glaucoma diagnosis and monitoring progression.

Aim:
To measure the peripapillary RNFL thickness, the pattern of RNFL defect, and association of RNFL with the severity of glaucoma using Spectralis Spectral Domain – OCT in patients with primary open-angle glaucoma (POAG) at a glaucoma clinic in a tertiary care teaching hospital in south India.

Methods:
Cross-sectional study design. Peripapillary RNFL thickness of 109 glaucomatous eyes of 56 patients aged 40–75 years having POAG, ocular hypertension, or suspected to have glaucoma but without visual field (VF) defects were included in the study. The cross-sectional thickness of RNFL using a 3.46 mm circle centered around the disc in 6 segments were measured and defects in the RNFL were identified by comparing measurements from each patient with the normative database.

Results:
The study included 109 eyes with 51 (46.79%) preperimetric eyes and 58 (53.21%) POAG eyes (with field defects). The average global thickness in the study population was 91.31 ± 12.81 µm for preperimetric eyes and 67.76 ± 17.33 µm for eyes with glaucoma. There was significant thinning in all segments between eyes with POAG and normal eyes with the mean difference highest in the inferotemporal segment (mean difference of 73.05) and the superotemporal segment (mean difference of 55.85). The global RNFL thickness had a coefficient of − 0.015 (standard error [SE] 0.003, 95% confidence interval [CI]: 0.02–0.009, R2 = 0.29) for mild glaucoma, −0.010 (SE 0.004, 95% CI: 0.02–0.003, R2 = 0.12) for moderate and − 0.18 (SE: 0.001, 95% CI: 0.022–0.014, R2 = 0.60) for severe glaucoma compared to preperimetric eyes in a linear regression model that adjusted for age and gender. Global and sector-wise RNFL thickness also had a significant area under Receiver Operator Characteristic (0.84, 95% CI: 0.78. 0.91) that showed the ability to discriminate between preperimetric and glaucomatous eyes. Possible “floor effect” of RNFL thickness was shown by 7 eyes with advanced glaucoma cases.

Conclusion:
RNFL thinning can be used as a parameter to assess glaucomatous structural loss that can aid in early diagnosis and monitoring of disease progression, to grade the severity of the disease in primary open-angle glaucoma, and when VFs cannot be done.
Visual outcome with sclerocorneal contact lens in case of a pellucid marginal degeneration
Authors: Husna. K 
Published: May 2023

ABSTRACT
A 40-year-old male presented with progressive dimness of vision in right eye. Slit-lamp microscopy revealed features of pellucid marginal degeneration in right eye. Corneal topography showed “crab-claw” pattern of thinning. His visual acuity in right eye improved well with sclerocorneal contact lens.
ESPESSURA DA CAMADA ÍNTIMA-MÉDIA DA PAREDE ARTERIAL CAROTÍDEA E O ÍNDICE APNEIA-HIPOPNEIA
Authors: Cavaco Mariana , Mateus Sonia , Carvalho Lucinda , Coelho Patrícia , Rodrigues Francisco 
Published: May 2023

As doenças cardio-cerebrovasculares são das principais causas de morte no mundo e a ateromatose o seu principal motivo, traduzindo-se inicialmente na espessura da camada íntima-média arterial. Cada vez mais prevalente, a apneia do sono apresenta efeitos negativos no sistema cardio-cerebrovascular. A sua gravidade pode ser quantificada pelo índice apneia-hipopneia.
Objetivou-se avaliar a relação da espessura da camada íntima-média carotídea em indivíduos com apneia do sono com o grau de gravidade da mesma, através de um estudo observacional, longitudinal, retrospetivo e quantitativo com recolha de base de dados de amostra do tipo não probabilístico por conveniência, constituída por 67 indivíduos.
A análise estatística realizou-se através do programa IMB SPSS Statistics, com calculo de medidas descritivas e Teste Qui-Quadrado (p<0,05).
Neste estudo, apenas 20 indivíduos com apneia do sono apresentavam espessamento da camada íntima-média, sendo que 11 apresentavam apneia grave e 6 moderada. Verificou-se que a relação dos graus de gravidade da apneia do sono com o índice íntima-média não é estatisticamente significativa (p=0,523).
Concluiu-se que em indivíduos com valores aumentados da espessura da camada íntima-média das artérias carótidas existe maior número de indivíduos com graus mais graves do índice apneia-hipopneia, sendo mais prevalente no sexo masculino.
Biosynthesis of Reduced graphene oxide nanoparticles from Uropathogenic K.oxytoca
Authors: Alzubaidy Fatima Hamza , Al-Hadad Ayaat , Abdul-Zahra Noor I. 
Published: May 2023

With advantages over physical and chemical methods from an economic and environmental standpoint, bioproduction possibilities for nanoparticles are becoming a very important topic. The current study's objective is to synthesis of reduced graphene oxide nanoparticles from Klebsiella oxytoca that cause urinary tract infections and characterized the synthesized biogenic nanoparticles by different method for characterization include Fourier transform infrared, energy dispersive spectroscopy, and scanning electron microscopy.
CONCLUSIONS
The isolated K.oxytoca from urinary tract infections have the ability to biosynthesized of reduced graphene oxide nanoparticles with size range from 35-85 nm and average diameter was 49.31 , the EDS determine the elemental analysis of rGO that contained carbon, oxygen, nitrogen, phosphate, and chloride and many active group detected by FTIR technique .
Zoning System Policy Model in Accepting New Students in Indonesia
Authors: Kosasih Fitriyani , Rochmani Rochmani , Folia Roli Cahya 
Published: May 2023

This study aims to see and describe the implementation of the Van Meter and Van Horn policy models. The results of this study are: 1) Implementation and communication activities between policy implementing organizations have been implemented, but the results have not been optimal, 2) The characters of Public Senior High School 2 Ciamis as implementers have understood the policy context well, are consistent with the goals and objectives and Policy objectives, implement prospective students firmly and strictly on policy rules, and supervise Zoning System policies following student recruitment technical guidelines and SOP, but the results are optimal, 3) The disposition as policy implementers has not seen what to do, can do these policies and have the commitment to implement student recruitment policies for optimal system zoning systems, 4) Social, economic and political conditions have influenced policy policies, 5) The zoning of system policy implementation has a positive impact on service policies and the quality of education services. This research concludes that Public Senior High School 2 Ciamis has implemented a zoning system policy, but it has yet to be optimal.
Hubungan Pilkada Dengan Perencanaan Wilayah Di Kec. Siborongborong
Authors: Milanie Feby , Sari Ayu Kurnia , Mardia Asiafinur 
Published: May 2023

Siborongborong merupakan salah satu kecamatan yang berada di kabupaten Tapanuli Utara. Siborongorong merupakan kecamatan yang terdapat bandara international dengan nama bandara silangit. Potensi yang ada di kecamatan Siborongborong terbilang besar diantaranya adalah potensi lahan yang subur, domestik pemandangan dan tempat rekreasi yang ada dan di jadikan sebagai nationl geology. Perencanaan wilayah merupaka salah satu bagian yang terpenting dalam meningkatkan pendapat di wilayah tersebut. Perencanaan wilyah yang baik dapat meningkatkan PAD disuatu daerah tesebut. Pilkada atau pemilihan perangkat daerah bagian yang paling terpenting yang tidak pernah dilewati oleh masyarakat di Siborongborong. Tujuan penelitian adalah untuk mengetahui hubungan pilkada dengan perencanaan wilayah di kecamatan siborongborong. Metode penelitian yang digunakan bersifat deskriftif, pengumpulan data dilakukan secara kuantitatif dan bersumber dari review jurnal yang di publish. Hasil penelitian ini adalah masyarakat sekitar menyambut antusias yang sangat tinggi dengan adanya kegiatan tersebut pilkada sehingga kepala daerah dapat memajukan wilayahnya. Dari hasil penelitian adanya hubungan pilkada dengan perencanaan wilayaah di kecamatan Siborongborong. Hal ini dikarenakan pemilihan kepala daerah dilakukan dengan antusi agar kepala daerah yang terpililh di dalam pilkada akan merencakana perencanaan wilayaah dan memajukan daerahnya, sehingga dapat meningkatkan pendapatan daerah di Siborongborong. Kesimpulan dari penelitian ini adalah dari hasil penelitian ini menyatakan bahwa semangat dan antusias masyarakat dalam menyambut pilkada ini sangat luar biasa. Perencanaan wilayah akan dilakukan setiap daerah yang sudah mendapatkan hak sebagai kepala daerah. Hubungan pilkada dengan perencanaan wilayah di Siborongborong sangat erat kaitannya, hal ini dikarenakan dengan adanya pilkada masyarakat sudah menaruk harapan yang besar dengan kepala daerah tersebut untuk memajukan dan merencanakan perkembangan wilayah di masing-masing kelurahan yang ada di kecamatan Siborongborong
Social and biological factors related to the development of climacteric syndrome in women from Kyrgyzstan
Authors: Teppeeva Tanzilya , Karymshakova Kanysh , Makenjan Uulu Almaz , Zhumabekova Altynai 
Published: May 2023

Introduction and Aim: Climacteric syndrome (CS) is observed in 50–80% of women over 50 years of age, which is related to the most common age-specific diseases in women. The objective of this study is to evaluate social and biological factors of the development of menopausal disorders and their incidence in women from Kyrgyzstan.

Methods: This is a cross-sectional study conducted on 1465 women aged between 35–64 years. Premenopausal and postmenopausal (<10 years) women from Kyrgyzstan were included and women with surgical menopause were excluded from this study.

Results: The mean age of perimenopause and postmenopause onset was 44.4 ± 3.66 years and 48.26 ± 3.87 years. Analysing gynecologic history in examined women reported that 46% and 25.5% suffered from menstrual disorders and premenstrual syndrome. Considering comorbidities, in examined women hypertension (48.9%), thyroid gland diseases (50.2%), gastrointestinal tract and hepatobiliary system diseases (39.6%), obesity (36.9%), and urinary system diseases (26.6%) were observed.

Conclusion: Even though there are some researchers who studied social and biological factors of the development of menopausal disorders, their nature, and incidence in women from Kyrgyzstan, this study is necessary for solving the problems in medical care and management of CS in women with comorbidities and gynecologic histories.
Neonato de 39 semanas de gestación con taquipnea transitoria, criptorquidia e hidrocele, con el modelo de Dorothea E. Orem
Authors: Villanueva-Vera Diana Yessica , Sánchez-Villasana Gabriela 
Published: May 2023

Introducción: a nivel mundial la taquipnea transitoria del recién nacido se presenta entre el 0.3 y 0.5 % de todos los recién nacidos, aunque existen algunas series mexicanas que reportan hasta el 2 % de todos los recién nacidos vivos. Comprende entre el 35 y 50 % de todos los casos de dificultad respiratoria no infecciosa que ingresan a los cuneros patológicos o unidades de cuidado intensivo neonatal.1 Mientras que las tasas de criptorquidia e hidrocele son más altas en los niños nacidos por cesárea (3.3 y 4.7 %, respectivamente), en comparación con los obtenidos por vía vaginal (1.7 y 1.6 %).2
Descripción del caso: neonato de 39 semanas de gestación con taquipnea transitoria del recién nacido, criptorquidia e hidrocele atendido en el servicio de atención al recién nacido de un hospital de segundo nivel de atención.
Objetivo: proporcionar cuidados especializados, utilizando el proceso de atención de enfermería basado en los conceptos teóricos del modelo de autocuidado de Dorothea E. Orem.
Método: estudio de caso, dado que en este diseño se observan los fenómenos en su contexto natural, el cual se realizó en la tercera semana de mayo 2021. Consideraciones éticas: se tomaron en cuenta aspectos bioéticos para la investigación clínica basada en evidencia científica, como la ley de Helsinki y el código de Nuremberg. Resultado: se logró que el neonato y su cuidador primario alcanzaran las metas propuestas al inicio del ingreso hospitalario, mediante la continua capacitación sobre los cuidados generales del recién nacido.
Conclusión: la taquipnea transitoria, criptorquidia e hidrocele son alteraciones que pueden ser detectadas al momento de la exploración al neonato.
Literature Analysis on Stachybotrys chartarum and Connections to Sick Building Syndrome
Authors: Pert Allison 
Published: May 2023

Sick building syndrome is defined as components of infrastructure that are harmful to human health in various ways ranging from noxious, harmful building materials to toxic fungal contaminants (1). There is mounting emphasis on the need for healthy, sustainably developed buildings as the amount of scientific literature published about sick building syndrome increases. Specifically, there is growing attention regarding the presence of contaminant fungi in buildings and the possible adverse human health effects upon exposure (2). Further, the estimated prevalence of Canadian homes with indoor mold growth is pervasive due to unwanted moisture accumulation in building structures (3). Despite the increasing abundance of scientific research, the existing literature does refer to established knowledge gaps; this includes the need for more primary, quantitative research observing the health effects of indoor mold exposure (3). Black mold (Stachybotrys chartarum) is thought to induce a variety of respiratory, mucosal, and dermatological symptoms in humans (1, 3, 4). These symptoms may arise by direct exposure to spores, indirect exposure or hypersensitivity to fungal antigens, or exposure to mycotoxins which may make inhabitants of contaminated buildings chronically ill (3). Mycotoxins are metabolite products of molds, typically found in mold spores which are the agents of sexual reproduction. The pathogenesis of mold sickness varies from species to species, but all molds found indoors should be treated as a potential hazard risk due to the unknown range of possible consequences after exposure (5). A comprehensive literature review examining the potential health effects of black mold exposure will help to emphasize and articulate the need for employers and homeowners to prioritize building decontamination.
Pandemi Covid 19 : Implikasi pada Pemilihan Kepala Desa Serentak Tahun 2021 di Kabupaten Bandung
Authors: Siwi Galih Raka 
Published: May 2023

Pandemi covid-19 mulai ditemukan pada Negara Indonesia tahun 2019. Adanya pandemi covid-19 bukan hanya berdampak pada bidang ekonomi, pendidikan, peradilan, bahkan hampir ke seluruh bidang kehidupan termasuk pemerinatahan nasional. Gelaran pilkades yang seharusnya diadaka di bulan Juli terpaksa ditunda hingga beberapa kali penundaan, itu merupakan salah satu akibat adanya pandemi covid-19. Tujuan penelitian ini untuk mengetahui implikasi serta faktor yang mempengaruhi penyelenggaraan pemilihan kepala desa serentak tahun 2021 di Kab. Bandung. Metode penelitian yang digunakan ialah deskriptif analisis dengan metode kualitatif. Hasil dari penelitian ini ialah, pertama, adanya berbagai penyesuian dan menuntut perubahan terhadap regulasi (Peraturan Daerah dan Perbup Kab. Bandung) untuk menyesuaikan dengan pandemi covid-19 dengan aturan ketat dalam hal protokol kesehatan agar pilkades ini tidak sebagai klaster covid-19 serta keselamatan rakyat tetap terjaga. Kedua, Covid-19 berpengaruh terhadap jalannya pilkades serentak ini serta terhadap para pihak yang terlibat dalam pilkades. Ketiga, faktor kesehatan, faktor regulasi, faktor anggaran, faktor kepemimpinan kepala desa, dan faktor penyelenggaraanpun.Kata kunci : Covid-19, Pilkades, Kabupaten Bandung
Античность в концептах национального строительства в межвоенной Европе: идеология режима И. Метаксаса в Греции (1936–1941)
Authors: Сапожникова Мария Григорьевна 
Published: May 2023

Древность как концепт национального строительства в Центральной и Восточной Европе, особенно межвоенного периода, вызывает большой интерес как феномен рецепции античности. Данная статья раскрывает причины обращения режима И. Метаксаса (1936–1941) к античному прошлому его государства. В начале XX в. среди греческой интеллигенции появились убеждения об уникальности греческой нации в плане создания сразу двух цивилизаций – античной, а затем византийской. Пока в Европе набирали силу новые идеологии – нацизм, фашизм, греческое правительство искало свой самобытный путь, поскольку шансы реализации «Великой идеи» стали ничтожными к 1922 г., а либерализм премьер-министра Э. Венизелоса потерпел крах в 1929 г. Поэтому для Иоанниса Метаксаса было важно найти опору для своего режима, которая бы основывалась на традициях, добродетелях, идеалах и героях легендарного античного прошлого. Такой идеологией стала «третья греческая цивилизация».
PENGEMBANGAN POTENSI BUDAYA WISATA KULINER PASAR KAMU (PEKAN SARAPAN KARYA ANAK MUDA) DESA DENAI LAMA, PANTAI LABU KABUPATEN DELI SERDANG
Authors: Pujiati Pujiati , Ritha Dalimunte  , Khairina Khairina , Fanindia Purnama  
Published: May 2023

Pengembangan wisata kuliner terkesan masih terabaikan, padahal jika mampu dikelola secara maksimal dapat medongkrak kunjugan wisatawan. Bagi rakyat Indonesia, masyarakat Sumatera Utara dan Kabupaten Deli Serdang. Istilah wisata sebenarnya tidak asing lagi, karena mayoritas daerah mempunyai potensi wisata, hanya perlu dibangkitkan dan dikembangkan. Selama ini pemerintah yang dikelola oleh Dinas Pariwisata cenderung hanya fokus pada wisata alam dan lainnya. Tujuan kegiatan ini memberdayakan masyarakat dan pedagang kuliner dalam pengembangan wisata budaya kuliner yang minim belum secara maksimal diberdayakan. Pasar Kamu merupakan icon tempat wisata kuliner yang perlu dikembangkan. Metodenya FGD, edukasi, ceramah, diskusi, tanya jawab dan pendampingan. dan pelatihan IT, manajemen dan marketing serta budaya pelayanan yang perlu ditingkatkan. Hasil pengabdian masyarakat ini adalah pengembangan potensi pariwisata berbasis kuliner sangat menarik untuk dikembangkan di masyarakat, di satu sisi memberikan dampak positif bagi penerimaan daerah dan memberikan manfaat bagi penumbuh-kembangan industri kreatif yang berpengaruh bagi peningkatan pendapatan perkapita di daerah dan khususnya masyarakat di kampong tsb. Pengabdian masyarakat tentang wisata berbasis kuliner dapat dilakukan dengan berbagai model pendekatan, misalnya dari aspek historis, keterlibatan atau partisipasi publik, cost budgeting, managemen marketing, sosio-ekonomi-budaya, literasi digital bagi pengelola dan mitra dan juga eksibisi yang dipromosikan.
MEMBINA MAHASISWA AKTIF PRODI D3 ANAFARMA DALAM BERWIRAUSAHA PEMBUATAN DAN PEMASARAN BAWANG HITAM (BLACK GARLIC)
Authors: Patimah Patimah , Dodi Irwandi  , Joko Sulistiyo  , Arni Widyastuti  
Published: May 2023

Bawang putih dengan pemanasan menghasilkan bawang hitam (black garlic) sehingga memiliki rasa yang gurih, berwarna hitam, sedikit manis, bertekstur lembut, dan kenyal . Sebagai bentuk pengamalan Tri Darma Perguruan Tinggi, Politeknik Kesehatan Kementerian Kesehatan Jakarta II Program Studi Diploma III Analisis Farmasi dan Makanan melaksanakan kegiatan pengabdian masyarakat. Tujuan untuk membina mahasiswa aktif Prodi D3 Anafarma Poltekkes Kemenkes Jakarta II tentang cara pembuatan dan pemasaran bawang hitam (Black garlic). Manfaat yang dapat diperoleh binaan dari kegiatan ini antara lain dapat membuat bawang hitam (black garlic) dan memasarkannya baik secara online maupun offline. Metode yang digunakan merupakan pelatihan dan pendampingan yang terdiri dari: pelatihan pembuatan bawang hitam dengan menggunakan alat yang sederhana, pelatihan pembuatan label kemasan, pendampingan pembuatan nama produk, dan pelatihan pemasaran produk. Hasil dari kegiatan ini dapat menghasilkan calon wirausahawan baru yaitu mahasiswa aktif telah melakukan pemasaran secara offline sebanyak lima paket dan secara online sebanyak sepuluh paket, Kegiatan terebut dapat diambil kesimpulan yaitu menciptakan satu tim mahasiswa aktif Prodi D-III Analisis Farmasi dan Makanan menjadi wirausaha baru.
A saúde mental dos estudantes universitários da área da saúde: uma revisão integrativa de literatura
Authors: Costa Murilo Marques , Nunes Renata Sousa , Pereira Alessandra dos Santos , Selari Leandro da Silva , Ferreira Geisenely Vieira dos Santos , Scalabrine Christiny Leal de OLiveira , Lúcio Drielly Neres , Pires Roseli Vieira 
Published: May 2023

Introdução: Compreende-se que os discentes dos cursos da área da saúde, durante sua formação, são capacitados para lidar com o indivíduo como um todo. Porém, muitas vezes, ao se preocupar com o estado de saúde dos pacientes que irão atender, descuidam da própria saúde durante o processo de formação acadêmica. Nos últimos anos, e mais acentuadamente nos que sucedem a pandemia da COVID-19, estudos apontam que uma crescente de doenças emocionais tem acometido estudantes das universidades brasileiras. Objetivo: Analisar as principais publicações nacionais e internacionais acerca da saúde mental dos estudantes universitários da área da saúde. Metodologia: Trata-se de uma revisão integrativa, em que a questão norteadora da pesquisa foi: Quais as publicações nacionais e internacionais acerca da saúde mental dos estudantes da área da saúde? As estratégias de buscas se deram nas bases de dados da Biblioteca Virtual de Saúde (BVS), Periódicos da Capes, Pubmed e Scielo. A busca dos artigos foi realizada no período de janeiro de 2023.
PENGARUH RASIO FINANCIAL LEVERAGE DAN LIKUIDITAS TERHADAP PROFITABILITAS PERUSAHAAN SEKTOR MANUFAKTUR PERIODE 2019-2021
Authors: Andriani Ria Fitria , Agatha Lia 
Published: May 2023

This thesis discusses the effect of financial leverage and liquidity ratios on company profitability. This type of research is quantitative research with hypothesis testing. The research sample is the financial statements of 30 manufacturing sector companies listed on the Indonesia Stock Exchange for the 2019-2021 period. The source of research data is secondary data obtained from the official website of the Indonesia Stock Exchange, namely www.idx.co.id. The data
analyzed are profitability (variable Y) using Return On Asset (ROA) analysis, financial leverage variable (variable X1) using Debt to Asset Ratio (DAR) analysis, and liquidity variable (variable X2) using Current Ratio (CR) analysis. The results of the research that tested the hypothesis obtained data: (1) The financial leverage ratio (DAR) has a negative and significant effect on the profitability (ROA) of manufacturing sector companies on the Indonesia Stock Exchange for the period 2019-2021; (2) The liquidity ratio (CR) has a positive and significant effect on the profitability (ROA) of manufacturing sector companies on the Indonesia Stock Exchange for the period 2019-2021; (3) The ratio of financial leverage (DAR) and liquidity (CR) simultaneously has a positive and significant effect on the profitability (ROA) of manufacturing sector companies on the Indonesia Stock Exchange for the period 2019-2021.