bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integrated vegetation management within electrical transmission landscapes promotes floral resource and flower-visiting insect diversity
Authors: Kimmel Chase B. , Oliveira Ivone de Bem , Campbell Joshua W. , Khazan Emily , Bremer Jonathan S. , Rossetti Kristin , Standridge Matthew , Shaw Tyler J. , Epstein Samm , Tsalickis Alexandra , Daniels Jaret C. 
Published: August 2023

Abstract

Context
Electrical transmission rights-of-way (ROW) are ubiquitous and critical infrastructure across the landscape. Active vegetation management of these ROW, a necessity to deliver electricity more safely, maintains these landscape features as stages of early successional habitat, a rarity in many regions, making these areas viable movement corridors for many taxa.
Objectives
The goals of this study were to (i) evaluate the effects of different landscape management practices on flowering plant and flower-visiting insect diversity and (ii) generate conservation management inferences considering electrical transmission landscape management.
Methods
In this study we tested the impact of three vegetation management levels across 18 sites. We evaluated the effects of treatment on bloom abundance and species richness as well as flower-visiting insect abundance and family richness.
Results
We identified 76541 flowers/inflorescences across 456 transects, including 188 species in 56 plant families. Additionally, we obtained data on 11361 flower-visitors representing 33 families from 2376 pan trap sets. High vegetation management favored the reduction of coarse woody debris in the sites and harbored the highest level of diversity of both floral resources and flower-visiting insects.
Conclusions
We show that we can align social and ecological values of ROW, ensuring their sustainability by applying regular and targeted integrated vegetation management. Thus, we can use ROW landscapes not only as an effective management strategy for the delivery of essential human services, but also to provide conservation benefits for wild pollinators.
Algae induced tritium organification promotes human exposure risk
Authors: Mao Liang , lu kun , Miao Yu , Dong Shipeng , Cui Fengmei , Zhang Yanxu , Diwu Juan , Chai Zhifang , Wang Shuao 
Published: August 2023

Abstract

The human radiation exposure caused by tritiated water (HTO) release has long been underestimated due to neglecting the transfer of its bioconversion products (organically bounded tritium, OBT) along the food chain. Here we systematically assessed the enrichment and organification of tritium (3H) by algae and the transfer OBT in the marine food chain. We found that algae rapidly incorporate and transfer HTO into OBT as part of nutrients for trophic transfer to fish, specifically retaining in brain to conduct behavioral toxicity. Additionally, the obtained concentration factors (CF) and transfer factors (TF) are crucial for estimating internal exposure dose to human individuals (IEDI), providing more rigorous risk assessment for planted 3H release and some leakage accidents.
Quick Porting of Virtual Simulation Experiment Interactions from the Web 3D to VR
Authors: Liu Dexin , Chen Hengxin 
Published: August 2023

Abstract

Virtual reality (VR) technology is developing rapidly, and many 3D virtual simulation experiments on the web can be quickly ported to the VR environment to enhance user experience. The manner of interacting with a quickly ported two-dimensional user interface (2DUI) is a matter of preference. In this study, we focused on finding a more effective interaction scheme when a web 3D virtual simulation experiment is ported into the VR environment. When the development time is short, ray interaction and touch interaction can be easily and quickly ported while retaining the 2DUI of the original web-side experiment. We selected the architecture optics virtual simulation experiment for porting, divided the interactions into two levels, namely, L1 ray and L2 touch interactions, and recruited 30 volunteers to participate in the experiment in groups. The efficiency and user experience of L1 and L2 were compared by designing interactive tasks and collecting data. Overall, L1 was more efficient than L2. For the four common user interfaces, buttons, sliders, toggles, and dropdowns, L2 was only slightly better at interacting with the dropdown boxes than L1. However, both were slower than the web interface. L2 also received higher workload scores, based on user feedback and workload surveys. We also designed an interaction level, L3, for VR with reference to Worlds in Miniature and compared it with L1/L2/web by using the same interaction tasks. L3 was as efficient as the web. Finally, based on the experimental results, we provide suggestions for quick porting development.
Effect of MoS2 decoration on energy storage of wheat straw-derived porous carbon for lithium-ion batteries
Authors: Jia Pengcheng , Liang Jicai , Yue Liufei , Liu Meina , Wang Xiaofeng , Liang Ce , Yu Kaifeng 
Published: August 2023

Abstract
In this paper, we report a simple and reliable hydrothermal carbonization method to prepare high-performance energy storage materials. Herein, Using wheat straw as a carbon source and ammonium ferrous sulfate hexahydrate (AFSH) as a regulator, porous wheat straw carbon (PWSC) materials were prepared by hydrothermal and high-temperature carbonization treatment. Using the obtained porous carbon as a carbon matrix, a triblock copolymer F127 was selected to control the morphology of MoS2, and a porous wheat straw carbon and flower-like MoS2 composite (PWSC@MoS2) was synthesized by hydrothermal method. The effects of the amount of structural modifier on the overall electrochemical properties of the composites were investigated. It was finally determined that the composite (PWSC@ MoS2-2) at the optimal structural modifier ratio of 1:2 showed high lithium storage capacity (907.8 mAh g− 1 after 300 cycles at 1C), excellent cycling stability and superior rate performance. Therefore, this efficient and environmentally friendly method of preparing PWSC@MoS2 composites from wheat straw can realize the secondary utilization of biomass waste and is a new choice of anode materials for lithium-ion batteries.
Significance of mitochondrial DNA in neonates with acute respiratory distress syndrome
Authors: Qi Lina , Su Chang , Zhou Qian , Jiang Junsheng 
Published: August 2023

Abstract
Background
To analyze peripheral blood mitochondrial DNA levels in neonates with neonatal acute respiratory distress syndrome(ARDS) and to assess their correlation with the severity of ARDS.
Method
Neonates diagnosed with ARDS from January 2021 to January 2023 were included as a study group prospectively. According to the Oxygen index (OI), they were divided into mild ARDS group (4 ≤ OI < 8), moderate ARDS group (8 ≤ OI < 16), and severe ARDS group (OI ≥ 16). The control group was selected from jaundiced neonates who were observed in the neonatal unit of the hospital during the same period. Peripheral blood samples were collected on days 1, 3, and 7 after admission in the ARDS group, and on admission in the control group. Real-time quantitative PCR was used to detect the expression levels of mtDNA and cGAS -STING mRNA, and ELISA was used to detect the levels of serum IL-6, IL-23, and IFN-γ. Pearson correlation analysis was used to assess the correlation between serum mtDNA and serum IL-6, IL-23, and IFN-γ levels.
Results
50 newborns were enrolled in the ARDS group, including 25 with mild ARDS, 15 with moderate ARDS, and 10 with severe ARDS, control group included 25 neonates. Compared with the control group, serum levels of mtDNA, cGAS -STING mRNA, IL-6, IL-23, and IFN-γ were significantly increased in the ARDS groups (P < 0.05). Compared with the mild ARDS group, serum mtDNA, cGAS -STING mRNA, IL-6, IL-23, and IFN-γ levels were significantly increased in the moderate and severe ARDS groups (P < 0.05). Compared with day 1, serum mtDNA, cGAS -STING mRNA, IL-6, IL-23, and IFN-γ levels significantly increased on day 3 and significantly decreased on day 7 in all ARDS groups (P < 0.05). Pearson correlation analysis showed that serum mtDNA levels were correlated with serum IL-6, IL-23, IFN-γ, and cGAS -STING mRNA levels (P < 0.05).
Conclusion
Elevated ARDS mtDNA levels may produce inflammatory mediators IL-6, IL-23, and IFN-γ by activating the cGAS -STING mRNA signaling pathway. MtDNA levels may have clinical value in assessing the severity of neonatal ARDS and in the earlier diagnosis of ARDS.
Different Surgical interventions for Unstable intertrochanteric fracture of the femur: Network meta-analysis
Authors: Zhou Yuqiao , Zhou Chunlin , Zhang Xiufang , Xun Yuhao , Feng Min , LIN JUN , Zhang Xiufang 
Published: August 2023

Abstract
Introduction: Although there is a large body of literature indicating the presence of unstable intertrochanteric femoral fractures (UIFF) surgical approaches to treatment, and studies that comprehensively evaluate treatment outcomes are limited. The purpose of this study was to compare the effectiveness of extramedullary [i.e.dynamic hip screw (DHS)], intramedullary [i.e. the proximal femoral nail (PFN)], and hemiarthroplasty (HA) for the treatment of UIFF using a network meta-analysis..
Methods: The Cochrane Database of Systematic Reviews, PubMed, EMBASE, Wanfang, and China National Knowledge Infrastructure (CNKI) databases were searched to identify randomised controlled trials (RCTs) . The primary outcomes were harris hip score、operation time、superficial wound infection、deep venous thrombosis、deep wound infection、implant cut out、varus malunion、bedsore and mortality (e search time was from the inception of each database up to November 2022. Following data extraction and quality assessment, network meta-analysis was conducted with Stata 16.0.
Results: A total of 15 RCTs were included, including 1282 patients. In comparison to the DHS, Harris hip score had the lowest values with PFN and HA [standardized mean difference (SMD) -1.38 (-2.25, -0.51)] and [SMD -1.50 (-2.31, -0.68)] respectively. DHS [SMD 2.18 (0.42,3.93) had a significantly longer running time in comparison to the PFN. In comparison to HA, there was a lower risk of Superficial wound infection with PFN [odds ratio (OR) = -1.07; The 95% confidence interval (CI): 0.48–0.73], DHS, and PFN were significantly more likely to have Implant clipped than HA [2.20 (0.76, 3.64)] and [1.88 (0.48, 3.28)], Compared with DHS, PFN 1.18 (0.02, 2.34) and HA 2.09 (0.97, 3.20) had a lower risk of Malunion.
Conclusion: The comprehensive comparison of the outcome indicators in 3 different treatments indicates that HA and PFN have good efficacy in improving HHS scores and avoiding joint deformities.while HA has a higher risk of superficial infection compared to PFN, which carries a risk of screw removal. However, it is impossible to find out more high-quality randomized controlled trials are needed to further confirm this in the future.
Level of Evidence: Level I
Inter-individual, hemispheric and sex variability of brain activations during numerosity processing
Authors: Zang Zhongyao , Chi Xiaoyue , Luan Mengkai , Hu Siyuan , Zhou Ke , Liu Jia 
Published: August 2023

Abstract
Numerosity perception is a fundamental and innate cognitive function shared by both humans and many animal species. Previous research has primarily focused on exploring the spatial and functional consistency of neural activations that were associated with the processing of numerosity information. However, the inter-individual variability of brain activations of numerosity perception remains unclear. In the present study, with a large-sample functional magnetic resonance imaging (fMRI) dataset (n = 460), we aimed to localize the functional regions related to numerosity perceptions and explore the inter-individual, hemispheric, and sex differences within these brain regions. Fifteen subject-specific activated regions, including the anterior intraparietal sulcus (aIPS), posterior intraparietal sulcus (pIPS), insula, inferior frontal gyrus (IFG), inferior temporal gyrus (ITG), premotor area (PM), middle occipital gyrus (MOG) and anterior cingulate cortex (ACC), were delineated in each individual and then used to create a functional probabilistic atlas to quantify individual variability in brain activations of numerosity processing. Though the activation percentages of most regions were higher than 60%, the intersections of most regions across individuals were considerably lower, falling below 50%, indicating substantial variations in brain activations related to numerosity processing among individuals. Furthermore, significant hemispheric and sex differences in activation location, extent, and magnitude were also found in these regions. Most activated regions in the right hemisphere had larger activation volumes and activation magnitudes, and were located more lateral and anterior than their counterparts in the left hemisphere. In addition, in most of these regions, males displayed stronger activations than females. Our findings demonstrate large inter-individual, hemispheric, and sex differences in brain activations related to numerosity processing, and our probabilistic atlas can serve as a robust functional and spatial reference for mapping the numerosity-related neural networks.
6mA-stackingCV: An improved stacking ensemble model for predicting DNA N6-methyladenine site
Authors: Huang Guohua , Huang Xiaohong , Luo Wei 
Published: August 2023

Abstract
DNA N6-adenine methylation (N6-methyladenine, 6mA) is a key regulation in the cellular processes. Precisely recognizing 6mA sites is of importance to further explore its biological functions. Although there are many computational methods developed for 6mA site prediction over the past decades, there is a large root left to improve. We presented a cross validation-based stacking ensemble model for 6mA site prediction, called 6mA-stackingCV. The 6mA-stackingCV is a type of meta-learning algorithm, which uses output of cross validation as input to the final classifier. The 6mA-stackingCV outperformed the state of the art performances in the Rosaceae independent test. Extensive tests demonstrated the stability and the flexibility of the 6mA-stackingCV. We implemented the 6mA-stackingCV as a user-friendly web application, which allows one to restrictively choose representations or learning algorithms. This application is freely available at http://www.biolscience.cn/6mA-stackingCV/.
Vaccination of autologous dendritic cells induces early protection against the Foot-and-mouth disease virus in pigs by enhancing T-cell immunity
Authors: Mu Su , Chen Ling , Li Shuai , Dong Hu , Zhang Yun , Yin Shuang , Tian Yunfei , Ding Yaozhong , Sun Shi , Shang shaobin , Guo Hui 
Published: August 2023

Abstract
Foot-and-mouth disease virus (FMDV) remains a challenge for cloven-hooved animals. The currently-licensed FMDV vaccines induce neutralizing antibody (NAb)-mediated protection but have early protection defects. Dendritic cell (DC) vaccines have shown great potency in producing rapid T-cell immunity in humans and mice. However, this strategy has not been elaborately explored in domestic animals, and it is unknown how much effectiveness can be achieved for a specific pathogen in pigs. In this study, we tested the potency of DC immunization in the protective immunity against FMDV in pigs. Autologous DCs were differentiated from each pig's periphery blood mononuclear cells, pulsed with inactivated FMDV (iFMDV-DC), and injected into the original pigs. The cellular immune responses and protective efficacy elicited by the iFMDV-DC were examined by multicolor flow cytometry and tested by FMDV challenge. The results showed that autologous iFMDV-DC immunization induces predominantly FMDV-specific IFN-γ-producing CD4+ T cells and cytotoxic CD8+ T cells (CTLs), high NAb titers, compared to the inactivated FMDV vaccine, and accelerated the development of memory CD4 and CD8 T cells, which was concomitantly associated with early protection against FMDV virulent strain in pigs. Early protection was associated with the rapid proliferation of secondary T cell response after the FMDV challenge and conferred more by secondary CD8 effector memory T cells rather than NAbs. These results demonstrated that rapid induction of cellular immunity by DC immunization is critical to improving early protection. To enhance cytotoxic CD8+ T cells in addition to Th1 immunity via a strategy or adjuvant comparable to DC immunization may facilitate the development of more effective FMDV vaccines and overcoming the defects of the current FMDV vaccines in the future.
The impact of maxillary dimensions on determining surgical approach of fungal ball in the maxillary sinus
Authors: Lee Young-Ha , Cho Won Ki , Kim Dong Hyun , Kim Ji Heui 
Published: August 2023

Abstract

Endoscopic middle meatal antrostomy (MMA) is commonly used for maxillary sinus (MS) fungal ball removal. For challenging cases involving anterior or inferior recess, an additional inferior meatal approach (IMA) might be needed. We analyzed the differences in MS dimensions on CT scans according to the surgical approach to suggest preoperative variables that could facilitate an additional IMA. CT scans of 281 adult patients who underwent ESS for the MS fungal ball (139 MMA, 62 MMA & IMA) were evaluated for comparative analysis of 8 MS measurements based on the surgical approach. Complete removal was achieved in all cases. Age and sex didn't differ significantly (p > 0.05). The maximum distances between the anterior-posterior walls, the inferior ostium border to the lateral recess, and the ostium to the inferior wall of the MS were statistically greater in the MMA & IMA group compared to the MMA group (p = 0.003, p = 0.005, and p = 0.010, respectively), especially among females. This study underscores the clinical importance of specific measurements—anterior to posterior wall, medial wall to lateral recess, and ostium to inferior wall of the maxillary sinus—for guiding optimal surgical approaches in MS lesions.
Stability analysis and Hopf bifurcation for two-species reaction-diffusion-advection competition systems with delays
Authors: Alfifi H. Y. 
Published: August 2023

Abstract
This paper examines a class of two-species reaction-diffusion-advection competition models with two time delays. A system of DDE equations was derived, both theoretically and numerically, using the Galerkin technique method. A condition is defined that helps to find the existence of Hopf bifurcation points. Full diagrams of the Hopf bifurcation points and areas of stability are investigated in detail. Furthermore, we discuss three different sources of delay on bifurcation maps, and what impacts of all these cases of delays on others free rates on the regions of the Hopf bifurcation in this model. We find two different stability regions when the delay time is positive ($\tau>0$), while the no-delay case ($\tau=0$) has only one stable region. Moreover, the effect of delays and diffusion rates on all free others parameters in this model have been considered, which can significantly impact upon the stability regions in both population concentrations. It is also found that, as diffusion increases, the time delay increases. However, as the delay maturation is increased, the Hopf points for both proliferation of the population and advection rates are decreased and it causes raises to the region of instability. In addition, bifurcation diagrams are drawn to display chosen instances of the periodic oscillation and two dimensional phase portraits for both concentrations have been plotted to corroborate all analytical outputs that investigated in the theoretical part.
Mathematics Subject Classification (MSC2010): 34K18; 35K57; 92D25; 35B35; 35B32; 35B10
Study on evolution law of pore characteristics of freeze-thaw coal based on fractal theory
Authors: Yuan Junwei , Chen Jianxun , Wang Yao , Xia Jingyi , Chen Min , Ge Tengfei , Nie Jinlong 
Published: August 2023

Abstract
To investigate the characteristics of pore structure change of coal under freeze-thaw cycles, the surface and internal pore structure distribution of coal samples with long flame and different freeze-thaw times were measured by scanning electron microscopy (SEM) and low-temperature nitrogen adsorption method, and the law of pore structure change of coal after freeze-thaw was analyzed by fractal theory. The results of scanning electron microscopy experiments show that after freeze-thaw, the phenomenon of crack pore enlargement on the surface of coal samples occurs to different extents, and the phenomenon of crack pore enlargement on the surface of coal samples increases with the duration of freeze-thaw; at the same time, the porosity and fractal dimension DS of microcracks on the surface increased by 214.2% and 8.8%, respectively, corresponding to the change of macrocracks. The low-temperature nitrogen adsorption results show that the freezing and thawing changes the internal pore structure from simple to complex, and the maximum nitrogen adsorption capacity, specific surface area and pore volume in the pore parameters increase by 67.57%, 49.12% and 35.55%, respectively, compared with those before freezing and thawing. After freezing and thawing, the fractal dimension of the pores decreased to different degrees in the high-pressure and low-pressure stages. It decreased by 6.6% in the high pressure stage and by 8.9% in the low pressure stage. The change in fractal dimension DL in the low-pressure stage is greater than that of fractal dimension DH in the high-pressure stage, and the difference between the two decreases with increasing number of freeze-thaw cycles.
Exploring shared genes and molecular mechanisms between primary Sjögren's syndrome and pulmonary hypertension based on transcriptome data
Authors: Yang yi , Xie Lili , Zhong Yinglian , Zhong Xiuqin , Jiang Shan , Du Haoming , Zhang Xiuling , Yu Le , Shang Jingjing , Fan Jie , Zhang Rongwei , Ren Jie , Duan Xinwang 
Published: August 2023

Abstract
Background Primary Sjogren's syndrome (pSS) is a chronic inflammatory autoimmune disease that mainly invades the salivary gland and lacrimal gland. Compared with other populations, pSS in Asian populations is more prone to pulmonary hypertension (PAH). Most of the studies on pSS-PAH are case-control studies with a small sample size, and few studies have explored its pathogenesis, especially at the gene level. The goal of this work is to investigate the shared molecular mechanism of the pSS and PAH genes.Methods After obtaining the expression profiles of pSS and PAH from the GEO database, we used limma software package to find the differential expression genes (DEGs) between the two diseases. In addition, we built protein-protein interaction (PPI) networks, carried out GeneMANIA analysis, immune infiltration analysis, gene set enrichment analysis (GSEA), TF-miRNA-hub regulatory network analysis, and chemical-gene interaction network analysis on these DEGs. Furthermore, the accuracy of the hub genes was evaluated using receiver operating characteristic (ROC) curves.Results As shared DEGs between pSS and PAH, we found a total of 18 elevated genes. The findings of the enrichment analysis revealed that these genes primarily regulate the viral immune defense response and the type I interferon signaling pathway. In the ROC curve study, six hub genes (IFIT2, IFIT3, RSAD2, PARP9, GBP1, and EPSTI1) shown good sensitivity and specificity. Immune infiltration study revealed that in both the pSS and PAH cohorts, Monocyte, MDSC, Central memory CD8 T cell, and Activated CD8 T cell had a high infiltration level. A TF-miRNA-hub regulatory network was built using validation data from databases, and it included 7 transcription factors (TFs), 157 miRNAs, and 6 hub genes. The CTD database constructed a Chemical–Gene network that included 204 chemicals and 6 hub genes, among which 4 chemicals were targeted by these 6 hub genes.Conclusion The six hub genes (IFIT2, IFIT3, RSAD2, PARP9, GBP1, and EPSTI1) might be exploited as biomarkers and therapeutic targets for pSS and PAH therapy. And they may play a biological function through modulating the viral immune defense response and the type I interferon signaling pathway. Cyclosporin may be an effective treatment for pSS in combination with PAH.