bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical features and risk factors of plastic bronchitis caused by refractory Mycoplasma pneumoniae pneumonia in children: a practical nomogram prediction model
Authors: Zhang Han , Yang Jingjing , Zhao Wenqi , Zhou Jing , He Shuangyu , Shang Yunxiao , Cheng Qi 
Published: January 2023

AbstractEarly assessment of refractory Mycoplasma pneumoniae pneumonia (RMPP) with plastic bronchitis (PB) allows timely removal of casts using fiberoptic bronchoscopic manipulation, which relieves airway obstruction and limit sequelae development. This study aimed to analyze clinical data for risk factors and develop a nomogram for early predictive evaluation of RMPP with PB. The clinical data of 1-14 year-old patients with RMPP were retrospectively analyzed. Patients were classified into a PB or non-PB group. The general characteristics, clinical symptoms, laboratory test results, imaging findings, and microscopic changes of the two groups were compared. A statistical analysis of the risk factors for developing PB was performed, and a nomogram model of risk factors was constructed. Of 120 patients with RMPP included, 68 and 52 were in the non-PB and PB groups, respectively. Using multivariate logistic regression analysis, fever before bronchoscopy, extrapulmonary complications, pleural effusion, cough duration, and lactate dehydrogenase (LDH) levels were identified as risk factors. A nomogram was constructed based on the results of the multivariate analysis. The area under the receiver operating characteristic curve value of the nomogram was 0.944 (95% confidence interval: 0.779-0.962). The Hosmer-Lemeshow test displayed good calibration of the nomogram (p = 0.376, R2 = 0.723).Conclusion: The nomogram model constructed in this study based on five risk factors (persistent fever before bronchoscopy, extrapulmonary complications, pleural effusion, cough duration, and LDH levels) prior to bronchoscopy can be used for the early identification of RMPP-induced PB.

What is Known:• Refractory Mycoplasma pneumoniae pneumonia (RMPP) in children has been increasingly reported and recognized, which often leads to serious complications.• Plastic bronchitis (PB) is considered to be one of the causes of RMPP, and bronchoscopic treatment should be improved as soon as possible to remove plastic sputum thrombus in bronchus.

What is New:• This study determined the risk factors for RMPP-induced PB.• The nomogram model constructed in this study prior to bronchoscopy can be used for the early identification of RMPP-induced PB, which facilitate the early bronchoscopic removal of casts, thereby promoting recovery and reducing cases with poor RMPP prognosis.
The mesenchymal circulating tumor cells as biomarker for prognosis prediction and supervision in hepatocellular carcinoma
Authors: Zhao Lina , Zheng Zhifa , Liu Yunhe , Liu Fei , Li Xiaoxin , Wu Zhihong 
Published: January 2023

Abstract
Purpose
Hepatocellular carcinoma (HCC) is one of the most common cancers and a leading cause of death worldwide. Accurate prognosis prediction tools are urgently needed. While the use of circulating tumor cells (CTCs) as prognostic prediction tool has a clear potential.

Methods
We established a comprehensive, negative enrichment-based strategy for CTCs analysis in patients with HCC, involving identification of epithelial CTCs (E-CTCs) and mesenchymal CTCs (M-CTCs) through specific biomarker. This strategy was performed in 127 HCC cases, 21 nonmalignant liver disease (NMLD) patients and 42 health control to analyze the relevance between CTCs and tumor recurrence.

Results
The total CTC number and M-CTC percent were positively correlated with tumor malignancy and high recurrence risk. Individually, preoperative total CTC number and M-CTC percent could robustly distinguish relapse cases from those with no relapse, with sensitivity of 80.95% and 90.48%, specificity of 74.12% and 84.71%, respectively. Levels of preoperative total CTC number and M-CTC percent can both be regarded as independent risk factors for HCC with early recurrence (P = 0.0053, P < 0.0001), and are both significantly correlated with worse recurrence-free survival (RFS) (log rank P < 0.0001; HR 7.78, 95% CI = 3.59–16.87; log rank P < 0.0001; HR 24.4, 95% CI = 8.67–68.77). The levels of total CTC number and M-CTC number had higher effectiveness than alpha fetal protein (AFP) in HCC longitudinal supervision (77.78% vs 88.89% vs 22.22%).

Conclusion
Preoperative and postoperative CTCs with higher effectiveness than AFP in prognosis prediction and recurrence supervision, indicating that CTCs could work as the biomarker for HCC clinical management.
Multiscale structural analysis of an Epiligurian wedge-top basin: insights into the syn- to post-orogenic evolution of the Northern Apennines accretionary wedge (Italy)
Authors: Stendardi F. , Viola G. , Vignaroli G. 
Published: January 2023

AbstractWedge-top basins represent useful tectonic elements for the characterisation of the evolution of their underlying accretionary wedge in space and time, as their final state of deformation sums up the bulk shortening and structural instability conditions of the wedge. Here, we present the geometric and kinematic patterns of deformation structures deforming the wedge-top Epiligurian basins of the Northern Apennines (Italy). Our main goals are to generate an evolutionary model to account for the syn- to post-orogenic evolution of the Epiligurian basins and to infer the building style of the Northern Apennines wedge during continental collision. Mesoscale structural analysis shows that common and widely distributed thrust and normal fault arrays deform the entire Epiligurian stratigraphic succession infilling the broadly E-vergent wedge-top basins. Thrusts are invariably cut by later NW–SE and NE-SW-striking normal and oblique fault systems characterised by fault planes that mutually intersect at all scales to form polygonal patterns. Remote sensing analysis of the tectonic structures affecting the Epiligurian formations confirms the variable orientation of both thrusts and normal faults within the different studied stratigraphic successions. As a whole, results suggest a polyphase tectonic evolution of the Epiligurian wedge-top basins during the widening of the Northern Apennines accretionary wedge towards the foreland by frontal accretion. The recognised main phases are: (i) syn-orogenic compression accommodating overall tectonic transport towards the eastern quadrants; (ii) post-orogenic extension genetically related to the extension of the inner zone of the Northern Apennines; (iii) more recent extension forming collapse-induced normal faults spatially arranged in polygonal patterns.
Giotto's Arena Chapel and the Triumph of Humility
Authors: Lange Henrike Christiane 
Published: January 2023

In this book, Henrike Lange takes the reader on a tour through one of the most beloved and celebrated monuments in the world – Giotto's Arena Chapel. Paying close attention to previously overlooked details, Lange offers an entirely new reading of the stunning frescoes in their spatial configuration. The author also asks fundamental questions that define the chapel's place in Western art history. Why did Giotto choose an ancient Roman architectural frame for his vision of Salvation? What is the role of painted reliefs in the representation of personal integrity, passion, and the human struggle between pride and humility familiar from Dante's Divine Comedy? How can a new interpretation regarding the influence of ancient reliefs and architecture inform the famous “Assisi controversy” and cast new light on the debate around Giotto's authorship of the Saint Francis cycle? Illustrated with almost 200 color plates, this volume invites scholars and students to rediscover a key monument of art and architecture history and to see it with new eyes.
Production et circulation des savoirs dans une monarchie polycentrique
Authors: Palomo Federico 
Published: January 2023

La production et la circulation des savoirs dans les contextes ibériques de l’époque moderne se trouvent au cœur de cet article. Plus précisément, celui-ci tente d’analyser les connexions qui, au-delà des liens politiques et commerciaux, se sont établies sur le plan de la culture lettrée entre plusieurs des espaces, africains, asiatiques et américains, où les Portugais étaient présents aux xvie et xviie siècles. L’étude vise à éclairer des circulations de savoirs peu explorées au sein de cette monarchie polycentrique. Celles-ci permettent d’observer la constitution de certains lieux en centres d’accumulation, de (ré)élaboration et de dissémination des savoirs produits dans le cadre des expériences ibériques dans les océans Indien et Atlantique. Ces circulations révèlent surtout des dynamiques qui, en marge de la communication avec les centres métropolitains, ont permis de connecter directement entre eux les espaces coloniaux.
Dietary diversity and associated factors among adult cancer patients attending treatment at Black Lion Specialized Hospital, Addis Ababa, Ethiopia
Authors: Girma Helen , Nana Amanuel 
Published: January 2023

Abstract
Background: Cancer has become a significant public health issue around the world and an increasingly important contributor to disease burdens. In countries like Ethiopia with high nutrient demands, people with chronic diseases like cancer are at a high risk of macro and micronutrient deficiencies. Therefore, the present study attempted to assess dietary diversity and associated factors among adult cancer patients attending treatment at Black Lion Specialized Hospital, Addis Ababa, Ethiopia. Method and Materials: Hospital-based cross-sectional study was conducted from 22 April 2021 to 22 May 2021 on 416 adult cancer patients at Black Lion Specialized Hospital (BLSH). A systematic random sampling technique was applied to select study subjects. Quantitative data were collected using a structured, pretested and interviewer-administered questionnaire. The questionnaire comprised the standard dietary diversity measurement tool, which was adopted from the Food and Technical Assistance (FANTA) then data were entered into EPI INFO software and analysed using Statistical Package for the Social Sciences (SPSS) version 25. Frequency, mean and standard deviation were used to describe variables. A binary logistic regression model was fitted to elicit factors associated with the dietary diversity of cancer patients and a P-value of less than 0⋅2 was used as a cut-off for further analysis. Logistic regression analysis with a 95 % confidence interval (CI) was estimated to measure the strength of association at P < 0⋅05. Results: The present study revealed that 61⋅5 % of patients had low dietary diversity. Being from a family size of five and more (AOR = 1⋅48, 95 % CI 1⋅28, 1⋅83), having no permanent income (AOR = 1⋅31, 95 % CI 1⋅15, 1⋅67), alcohol consumption (AOR = 3⋅97, 95 % CI 1⋅20, 13⋅1), not doing regular physical exercise (AOR = 1⋅83, 95 % CI 1⋅07, 3⋅12), lack of nutritional information (AOR = 2⋅23, 95 % CI 1⋅30, 3⋅82), poor nutritional knowledge (AOR = 1⋅84, 95 % CI 1⋅05, 3⋅25) and minimum meal frequency (AOR = 10⋅7, 95 % CI 5⋅04, 22⋅7) were factors associated with inadequate dietary diversity. Conclusion: The present study showed that the majority of cancer patients had low dietary diversity, suggesting that they are highly vulnerable to micronutrient deficiencies. Therefore, efforts should be strengthened to improve patients’ income level, access to nutrition information and nutritional knowledge.
Comparative analysis of machine learning algorithms for predicting standard time in a manufacturing environment
Authors: Çakıt Erman , Dağdeviren Metin 
Published: January 2023

AbstractDetermining accurate standard time using direct measurement techniques is especially challenging in companies that do not have a proper environment for time measurement studies or that manufacture items requiring complex production schedules. New and specific time measurement techniques are required for such companies. This research developed a novel time estimation approach based on several machine learning methods. The set of collected inputs in the manufacturing environment, including a number of products, the number of welding operations, product's surface area factor, difficulty/working environment factors, and the number of metal forming processes. The data were collected from one of the largest bus manufacturing companies in Turkey. Experimental results demonstrate that when model accuracy was measured using performance measures, k-nearest neighbors outperformed other machine learning techniques in terms of prediction accuracy. “The number of welding operations” and “the number of pieces” were found to be the most effective parameters. The findings show that machine learning algorithms can estimate standard time, and the findings can be used for several purposes, including lowering production costs, increasing productivity, and ensuring efficiency in the execution of their operating processes by other companies that manufacture similar products.
‘Success to the Shropshire Chamber of Agriculture’: a reappraisal of the role of chambers of agriculture in Britain during the late nineteenth and twentieth centuries
Authors: Bowen James P. 
Published: January 2023

AbstractThe central and associated county or district chambers of agriculture have attracted little attention from historians. Their origins have been attributed to the perceived lack of a national coordinating body for agriculture highlighted by the 1865–7 cattle plague. This article based on the records of the Shropshire Chamber of Agriculture, newspapers and printed histories reconsiders their role. Members were initially drawn from landowning society and larger tenant farmers, although membership widened with the growth of rival organisations. Activities included lectures, talks and debates on agricultural subjects, visits to farms, factories and the county agricultural college and farm institute, dinners and social occasions at which those interested in agriculture could meet. By foregrounding the people and politics of the chambers of agriculture, it is argued they need to be incorporated more fully into the historiography of agricultural and rural politics of Britain during the nineteenth and early twentieth centuries.
Adults with CHD balancing motivations and concerns in pregnancy decision-making
Authors: West Kathleen M. , Bayley Elizabeth , Pechan Jaimie , Engelberg Ruth A. , Albright Catherine , Buber Jonathan , Steiner Jill M. 
Published: January 2023

AbstractBackground:While the incidence of pregnancy has increased among individuals with adult CHD, little has been described about considerations and experiences of patients with adult CHD regarding pregnancy.Objective:We aimed to explore patients’ motivations, concerns, and decision-making processes regarding pregnancy.Methods:In April 2019–January 2020, we conducted in-depth telephone interviews with patients (n = 25) with simple, moderate, or complex adult CHD, who received prenatal care at the University of Washington during 2010–2019 and experienced a live birth. Transcripts were analysed using thematic analysis.Results:Participants described motivations for pregnancy as both internal desires (motherhood, marriage fulfillment, biological connection, fetal personhood, self-efficacy) and external drivers (family or community), as well as concerns for the health and survival of themselves and the fetus. Factors that enabled their decision to maintain a pregnancy included having a desire that outweighed their perceived risk, using available data to guide their decision, planning for contingencies and knowing their beliefs about termination, plus having a trusted healthcare team, social support, and resources. Factors that led to insurmountable risk in subsequent pregnancies included desire having been fulfilled by the first pregnancy, compounding risk with age and additional pregnancies, new responsibility to an existing child, and reduced healthcare team and social support.Conclusions:Understanding individuals’ motivations and concerns, and how they weigh their decisions to become or remain pregnant, can help clinicians better support patients with adult CHD considering pregnancy. Clinician education on patient experiences is warranted.
Cardiac arrest as initial presentation of pheochromocytoma in a young
Authors: Li Xuanxuan , Wang Renping , Yang Zhikai 
Published: January 2023

AbstractWe reported a case of pheochromocytoma with initial presentation of cardiac arrest. The patient underwent implantable cardioverter defibrillator for primary prevention but subsequently experienced repeated implantable cardioverter defibrillator shocks and syncopal episodes. A mass was found in the adrenal gland by CT, which was confirmed by anatomopathological analysis of the surgical specimen.
The unbearable lightness of being? Reconfiguring the moral underpinnings and sources of ontological security
Authors: Bolton Derek 
Published: January 2023

AbstractWhile ontological security (OS) studies have gone through a recent evolution, shifting toward psychoanalytic and existential accounts of anxiety, this article argues there remains a deficient engagement with the affective environments within which actors operate. Specifically, focusing on shared emotions/affect allows for a thicker account of the mechanisms of OS – including the constitutive forces underpinning society/societal trust, the role/power of signifiers and narratives, and the basis upon which actors promote social change. Accordingly, it suggests Durkheim's social theory, his broader concept of ‘religion’ as an affective community constituted by faith in a moral order entwined with the sacred, offers a viable pathway to develop these insights and develop a new basis for the mechanisms of OS. The drive for OS thus becomes reconfigured as an effort to act faithfully toward a dynamic moral order, while ontological insecurity emerges from the unbearable lightness of being experienced within moral disorder. Following Durkheim's preliminary argument on nationalism representing the continuation of religion, we can then revise how/why nations are integral to OS and International Relations. Specifically, we can view foreign policy as informed by debates around how to act faithfully toward the moral order – a process interrelated with revitalization and renewal of the sacred.
Shared Genetic Factors Contributing to the Overlap between Attention-Deficit/Hyperactivity Disorder Symptoms and Overweight/Obesity in Swedish Adolescent Girls and Boys
Authors: Javaras Kristin N. , Munn-Chernoff Melissa A. , Diemer Elizabeth W. , Thornton Laura M. , Bulik Cynthia M. , Yilmaz Zeynap , Lichtenstein Paul , Larsson Henrik , Baker Jessica H. 
Published: January 2023

AbstractAttention-deficit/hyperactivity disorder (ADHD) and obesity are positively associated, with increasing evidence that they share genetic risk factors. Our aim was to examine whether these findings apply to both types of ADHD symptoms for female and male adolescents. We used data from 791 girl and 735 boy twins ages 16−17 years to examine sex-specific phenotypic correlations between the presence of ADHD symptoms and overweight/obese status. For correlations exceeding .20, we then fit bivariate twin models to estimate the genetic and environmental correlations between the presence of ADHD symptoms and overweight/obese status. ADHD symptoms and height/weight were parent- and self-reported, respectively. Phenotypic correlations were .30 (girls) and .08 (boys) for inattention and overweight/obese status and .23 (girls) and .14 (boys) for hyperactivity/impulsivity and overweight/obese status. In girls, both types of ADHD symptoms and overweight/obese status were highly heritable, with unique environmental effects comprising the remaining variance. Furthermore, shared genetic effects explained most of the phenotypic correlations in girls. Results suggest that the positive association of both types of ADHD symptoms with obesity may be stronger in girls than boys. Further, in girls, these associations may stem primarily from shared genetic factors.
Discovery of a >1,000 km Cambrian Eclogite‐Bearing High‐Pressure Metamorphic Belt in the Central Asian Orogenic Belt: Implications for the Final Closure of the Pan‐Rodinian Ocean
Authors: Zhu Mingshuai , Zhang Fuqin , Smit Matthijs A. , Pastor‐Galán Daniel , Guilmette Carl , Miao Laicheng , Zou Yi , Yang Shunhu , Ganbat Ariuntsetseg , Tual Lorraine , Wang Zeli 
Published: January 2023

AbstractThe immense Central Asian Orogenic Belt (CAOB) records the transition from the Pan‐Rodinian Mirovoi Ocean to the Paleo‐Asian Ocean, but the final closure of the Mirovoi Ocean remains unexplored. Here we document two new eclogite occurrences, located between CAOB microcontinents and the Ediacaran–Cambrian island arc in Mongolia. Pseudosection modeling and geothermobarometry constrain peak conditions of ∼560°C and ∼2.2 GPa for the Urgamal eclogite and ∼715°C and ∼2.0 GPa for the Tsengel eclogite. Zircon U‐Pb dating results suggest the Urgamal eclogite‐facies metamorphism occurred at ∼522 Ma, and the granite gneiss enclosing the eclogite yielded ∼811 Ma crystallization age and ∼519 Ma metamorphic age. Detrital zircon age spectra of the paragneisses associated with the eclogite suggest a probable provenance from the adjacent Zavkhan microcontinent and the Neoproterozoic arc superimposed on the microcontinent. The Tsengel eclogite has a protolith age of ∼853 Ma and an eclogite‐facies metamorphic age of ∼522 Ma, and the associated migmatite gneiss record a ∼520 Ma migmatization event. The rock associations and geochemical affinities indicate that their protoliths represent mafic rocks formed in a continental rift setting and the Early Neoproterozoic subduction–accretion complex, respectively. Their similar tectonic position and metamorphic age suggest that these rocks are part of a single >1,000 km long Cambrian high‐pressure metamorphic belt. The rocks record closure of the Mirovoi Ocean within the CAOB and constrain this crucial event to ∼520 Ma along the western margin of the microcontinents in Mongolia.
LNOx Emission Model for Air Quality and Climate Studies Using Satellite Lightning Mapper Observations
Authors: Wu Y. , Pour‐Biazar A. , Koshak W. J. , Cheng P. 
Published: January 2023

AbstractA lightning nitrogen oxides (LNOx) emissions model using satellite‐observed lightning optical energy is introduced for utilization in Air Quality modeling systems. The effort supports assessments of air‐quality/climate coupling as related to the influence of LNOx on atmospheric chemistry. The Geostationary Lightning Mapper (GLM), International Space Station Lightning Imaging Sensor (ISS‐LIS), and the Tropical Rainfall Measuring Mission (TRMM) LIS data are used to examine the efficacy of the method, extend the previously derived LNOx record, and demonstrate a path for using ISS‐LIS observations to cross‐calibrate regional LNOx estimates from the future global constellation of geostationary lightning observations. A detailed evaluation of the GLM data set is provided to establish the robustness of observations for LNOx estimates and to make preliminary assessments of the LNOx emissions model. Seasonal and geographical variation, land/ocean contrast, and annual fluctuation in the GLM observed lightning activity and flash optical energy are provided. GLM detection substantially degrades with the increase in the field of view, resulting in 44% more flashes and 40% less optical energy observation by GLM‐16 (compared to GLM‐17) to the east of the middle‐longitude between the two mappers (106.2°W). Regular horizontal striations are found in the optical energy product. On average, GLM flashes matched to the cloud‐to‐ground flashes have ∼30% longer duration, 50%–70% more extension, and ≥100% higher optical energy compared to the unmatched flashes (assumed to be intra‐cloud). The results from summer‐long chemical transport simulations using LNOx generated from the emission model agrees with previous studies and shows consistency across the GLM/LIS data sets.