bluuebunny/crossref_metadata_2025_split huggingface dataset:
What you hear may not be what you see: Potential of citizen science methods to use bats as riverine forest quality indicators
Authors: López‐Bosch David , Blanch Estel , Páramo Ferran , Flaquer‐Sánchez Carles , López‐Baucells Adrià 
Published: September 2023

AbstractMediterranean habitats will be one of the Eurasian ecosystems more strongly affected by Climate Change, especially their riverine systems. Monitoring these ecosystems, which are endemism hotspots and extremely sensitive to changes in rain regimes and extreme weather events like droughts, is of crucial importance. Decades of citizen science projects have proven their utility in highlighting ecological shifts and conservation action priority areas. The Bat Monitoring Programme (www.batmonitoring.org), for instance, has already been used to develop ecological indicators to evaluate the evolution and conservation status of Mediterranean ecosystems. However, using bats as ecological indicators for aquatic ecosystems has resulted in contradicting results, making its application a little controversial. In the present study, we compared two citizen science protocols (visual counting vs. passive acoustic monitoring) used in the Bat Monitoring Programme to test the utility of trawling bats as indicators of Mediterranean riverine habitat quality at both local and landscape scales. By doing so, we aimed to build a specific ecological indicator to determine habitat quality through visual and acoustic counts. Although both protocols presented similar positive significant responses to riverine forest quality, visual counts are suggested as the best sampling approach due to their simplicity and potential within citizen science projects. Moreover, for the first time, we defined threshold values of trawling bat activity to assign different levels of habitat quality to the sampled rivers. We applied them in NE Iberia to exemplify the benefits of using them in a Mediterranean region and discussed the potential, pros and cons of these two citizen science methodologies to establish a pan‐European river biomonitoring programme using trawling bats.
Square Technique—A Treatment for Cellulite with Large Size Particle Hyaluronic Acid
Authors: de Matos Lourenço Luciana , Colla Lara Apendino , Ortiz de Noronha Maria Gabriela , Izzo Thomaz Rezende , Sigrist Rosa 
Published: September 2023

Abstract
Gynoid lipodystrophy, also called cellulite, is defined as a metabolic disorder of the subcutaneous tissue that alters body contour. It is rare in men but affects 80%–90% of adult women.The authors describe a technique for the treatment of cellulite with non-traumatic subcisionTM of septa by cannula associated with large-gel-particle hyaluronic acid (HA). It uses a special marking, a safe plan and a specific product. The product being used is Subskin Aeskins, in a subcutaneous plan as no major blood vessels were found.The authors report good aesthetic results with the proposed technique. The patients reported a high degree of satisfaction.The product chosen has high G prime and large particles, which accounts for resistance to deformation and a high lifting power. Moreover, HA is a biocompatible, absorbable product and considered a safe filler. This technique allows the treatment of an area with various surface irregularities.The Square Technique proved to be a minimally invasive technique, with fast results, no major risks and little downtime, bringing satisfaction to patients and improving their self-confidence and quality of life.
Rapid identification of chemical constituents of Chaihu‐jia‐Longgu‐Muli decoction based on ultra‐performance liquid chromatography‐quadrupole time‐of‐flight mass spectrometry coupled with the UNIFI platform
Authors: Wu Tong , Liu Yin , Dong Hanshuo , Ai Chunling , Sun Li 
Published: September 2023

AbstractChaihu‐jia Longgu‐Muli decoction (CLMD) is a traditional Chinese medicine formula, and it has been used for more than a thousand years to treat mental and nervous system diseases. However, the active constitutions of the CLMD are unclear. Accordingly, an integrated analysis based on the ultra‐performance liquid chromatography‐quadrupole time‐of‐flight mass spectrometry method combined with the UNIFI platform was used to clarify the chemical composition of the CLMD. As a result, 102 compounds including 38 saponins, 32 flavonoids, 12 polyphenols, nine anthraquinones, and 11 others were identified or tentatively presumed. Among them, 19 compounds were confirmed unambiguously with standards. Moreover, the characteristic fragmentations and fragmentation patterns of different compounds in CLMD were summarized, and each compound was classified as an individual herb. It was demonstrated that this method is rapid and accurate and could provide a strategy for the qualitative analysis of the chemical constituents of CLMD, and these results will provide experimental evidence for the subsequent studies on the pharmacodynamic material basis and quality control of CLMD.
Systems engineering and water resources management: A closer relationship is needed
Authors: Grigg Neil S. 
Published: September 2023

AbstractSystems engineering can be applied in a broad spectrum of sectors, but only its analysis tool has been applied in the field of water resources management. Because systems engineering has a separate community of practice from water resources, there is little crosstalk between the two fields. As a result, the systems engineering functions that support planning, design, production, procurement, and customer support are not being applied to water systems. Meanwhile, water systems exhibit complexities that have generated a separate field named Integrated Water Resources Management that continues to confuse its followers after several decades. Its methods are applied to a broad spectrum of water issues that affect multiple stakeholders with conflicting interests and involve distinct subsystems, such as water supply or hydropower, as well as combinations of them. Use of systems analysis for such water issues began six decades ago, but it is still a work in progress. Evolving methods of systems engineering offer new possibilities to address problems of water resources management, but they must extend beyond systems analysis, which belongs to multiple disciplines. Examples show possibilities to apply systems engineering methods when water issues exhibit attributes of engineered systems and do not involve social and environmental complexities that cannot be included in system boundaries. Collaboration among systems engineering and water resources management would offer a fertile test bed to advance both fields.
The impact of Geospatial Inquiry lessons on student interest in science and technology careers
Authors: Rubino‐Hare Lori , Whitworth Brooke A. , Boateng Francis , Bloom Nena 
Published: September 2023

AbstractAdvances in online geospatial technologies (GST) have expanded access to K‐12 classrooms which has implications for the support teachers require to effectively integrate GSTs to promote learning. Previous studies have shown the impact of GST‐integrated lessons on student engagement, spatial thinking skills, and/or content knowledge; however, most of these studies have been small in scope and scale and frequently focus on the affordances of the technology, without addressing the context of the implementation and student characteristics for whom GST is most impactful. We attempt to address some of these gaps. Our program scaled an effective GST‐focused professional learning and development program to a national audience through a facilitator development model. This paper explores the student characteristics and lesson factors that resulted in student interest in science and technology and careers in those fields. After teaching a Geospatial Inquiry lesson created during a teacher workshop, teachers (n = 82) submitted the lessons and surveys on the implementation of Geospatial Inquiry lessons. The implementation surveys and lessons were scored for alignment to the principles of high‐quality Geospatial Inquiry. Students (n = 1924) completed a post‐lesson retrospective survey and indicated the extent to which their perceptions and attitudes toward science and technology changed because of the lesson. Results indicate that teacher GST performance is associated with increases in student outcomes. Students with previous exposure to science activities were more likely to have increased interest and excitement in science and careers in science but decreased interest in technology careers. Students who had previous exposure to technology activities had increased interest and excitement in technology and careers in technology but decreased interest in science careers. Geospatial Inquiry lessons also had a significant impact on students who are traditionally underrepresented in STEM fields. After participating in the lessons, students who identify as female reported higher engagement and interest in science and higher interest in science careers. Students who identified as Black or Hispanic also reported higher interest and excitement in science and technology, and students who identified as Black reported marginally higher interest in science careers.
In Pursuit of Queer Inquiry with Turkish EFL Preservice Teachers
Authors: Güney Özge 
Published: September 2023

AbstractBased on queer critical literacies framework, this study describes an intervention that aimed to help preservice teachers identify and deconstruct heteronormative discourse in Turkish social and educational contexts. Through a local documentary that narrates the experiences of a Turkish transgender individual, preservice teachers critique the normal/abnormal binary as conditioned by social practices, power relations, and religion in Turkey. The study further explores the attitudes of preservice teachers towards incorporation of sexuality issues in the English classroom and in English language teaching programs with data from in‐class discussions and individual interviews conducted at three Turkish state universities. Certain methodological challenges I encountered during data collection are also presented to hopefully give insights to future researchers interested in exploring sexual diversity issues in similar settings. As for the findings, the study revealed that participants’ lived experiences of queer conversations with teacher educators enabled them to successfully identify and deconstruct heteronormative discourses in their programs. Their experiences as trainee teachers additionally showed that queer discussions, considered a taboo in the Turkish society, are inevitable in the English classroom. However, preservice teachers revealed certain reservations about how or whether they would adopt a queer friendly discourse in their future classrooms considering the strict government policies and high levels of religiosity in society. It is thus critical that (preservice) teachers in conservative communities be pedagogically prepared for future encounters of queer discussions to offer a respectful classroom environment for all learners. Queer critical literacies might be a useful framework for teacher educators to increase awareness of teachers about how dominant discourses may reinforce heteronormativity and how teachers could be agents of change by identifying and deconstructing such discourses to create a safe classroom environment for learners of diverse sexual identities.
Estrogen receptor alpha‐mediated mitochondrial damage in intrahepatic bile duct epithelial cells leading to the pathogenesis of primary biliary cholangitis
Authors: Liang Mengting , Ye Siwen , Jing Rubin , Zhu Bukun , Yuan Wenjie , Chu Xi , Li Ying , Zhang Wei 
Published: September 2023

AbstractThis study investigated the effects of estrogen and estrogen receptor alpha (ERα) on the pathogenesis of primary biliary cholangitis (PBC) in human intrahepatic bile duct epithelial cells (HiBECs). The researchers measured serum levels of ERα, oxidative stress indicators, and cytokines in PBC patients and healthy controls. They examined the expression of ERα, pyruvate dehydrogenase complex E2‐component (PDC‐E2), and apoptosis‐related proteins in the small bile ducts. In vitro experiments with HiBECs showed that estrogen had a dual effect on cell viability, increasing it at low concentrations but reducing it at higher concentrations. ERα activation led to mitochondrial damage, apoptosis, and upregulation of ERα and PDC‐E2 expression. These findings suggest that the high expression of ERα in the bile ducts contributes to mitochondrial damage, inflammation, and apoptosis in PBC. The study highlights ERα as a potential target for understanding and treating estrogen‐mediated PBC pathogenesis.
Catalytic pyrolysis of polypropylene and polyethylene terephthalate waste using graphene oxide‐sulfonated zirconia (GO‐Szr) and analysis of its oil properties for Bharat Stage VI fuel production
Authors: Rex Prathiba , Rahiman Mohammed Kalil , Barmavatu Praveen , Aryasomayajula Venkata Satya Lakshmi Sai Bharadwaj , Meenakshisundaram Nagaraj 
Published: September 2023

AbstractThis research work is focused on the production of liquid hydrocarbon fuel from plastic waste. To perform the experiments, polypropylene waste (PPW) and polyethylene terephthalate (PETW) were selected and pyrolyzed in a semi‐batch reactor at a temperature of 500°C. Nearly 72.28 wt.% of liquid fuel was recovered from 100 g of plastic waste feed through non‐catalytic pyrolysis process. The application of catalyst GO‐Szr to the pyrolysis process increased the oil yield to 92.76 wt.%. The oil properties were studied, to assess the characteristics and to compare with that of diesel fuel. The properties of oil were found to possess very good diesel properties such as kinematic viscosity of 2.18 mm2/s, density of 790 kg/m3, cloud and pour point less than −11°C, Sulphur content less than 3 ppm and cetane number was found to be as high as 72.44. From these studies, it is highlighted that waste plastics pyrolysis is a suitable option to produce diesel‐like fuel.
Spectral simulation of hydromagnetic flow with dissipative and radiative heat transfer over an inclined rotating disk within a non‐Darcy porous medium
Authors: Kumar Premful , Nandkeolyar Raj 
Published: September 2023

AbstractThe goal of the research presented in this paper is to examine how a magnetic field affects the unsteady flow of an incompressible nanofluid over a spinning disc that is inclined and stretched while the flow is embedded in a non‐Darcy porous medium. Furthermore, the heat transmission mechanism takes into account Joule heating and viscous dissipation. By imposing thermal radiation to enhance the heat transmission system under the effects of convection, the current article becomes more realistic. A set of nonlinear partial differential equations and associated boundary conditions defines the mathematical problem. Using an appropriate similarity transformation, the mathematical model is converted into a set of nonlinear ordinary differential equations with boundary conditions, which are then solved numerically by the Spectral Quasi Linearization Method (SQLM). Graphs and tables for various flow parameters illustrate the complete results for the exploration of dimensionless velocity and temperature. Regression analysis is used to statistically estimate the local Nusselt number and the skin friction coefficients. From the numerical results, it is found that when the magnetic parameter is increased, the flow velocity in the radial and tangential directions decreases due to the Lorentz force. With the variation of the Forchheimer number, the fluid flow in both directions decreases with increasing inertia coefficient. By increasing the magnetic parameter and Eckart number, the temperature of the fluid increases. The performed quadratic regression analysis reveals that the permeability of the medium and the generated Lorentz force are significant for the skin friction coefficient in the radial direction, whereas the stretching parameter and Forchheimer number are significant for the skin friction coefficient in the tangential direction. Thermal radiation and convective heating are found to significantly affect the heat transfer coefficient.
Thermally stratified Cu–Al2O3/water hybrid nanofluid flow with the impact of an inclined magnetic field, viscous dissipation and heat source/sink across a vertically stretching cylinder
Authors: Paul Ashish , Nath Jintu Mani , Das Tusar Kanti 
Published: September 2023

AbstractA numerical study of the thermally stratified flow of H2O based Cu − Al2O3 hybrid nanofluid over a linearly stretching cylinder placed vertically in a porous media has been performed. The influences of viscous dissipation, thermal source/sink, and an inclined magnetic field were also considered. Using appropriate similarity transformations, the non‐linear mathematical equations of the flow model are translated into a dimensionless form. The in‐build finite difference Matlab code Bvp4c is used to attain the numerical solution of the transformed non‐linear ordinary differential equations (ODEs). Influences of nanoparticles when added to the water and also the flow parameters’ impacts on the flow rate and thermal transport rate are shown in graphs and tables. The results showed that the absolute value of the shear stress of the hybrid nanofluids was enhanced by up to 33% compared to the considered nanofluid. The study also revealed that the heat transport rate in the convective flow region was much higher in hybrid nanofluid as compared to nanofluid. For Cu − Al2O3/water hybrid nanofluid, the temperature went negative for high thermal stratification. The present study has important implications for the design and optimization of heat transfer devices that use thermally stratified hybrid nanofluids. The results also provide novel insights into the flow behavior of these fluids, that can be used to improve our understanding of their physical properties.
Radioprotectors, Radiomitigators, and Radiosensitizers
Authors: Montoro Alegría , Obrador Elena , Mistry Dhruti , Forte Giusi I. , Bravatà Valentina , Minafra Luigi , Calvaruso Marco , Cammarata Francesco P. , Falk Martin , Schettino Giuseppe , Ahire Vidhula , Daems Noami , Boterberg Tom , Dainiak Nicholas , Chaudhary Pankaj , Baatout Sarah , Mishra Kaushala Prasad 
Published: September 2023

AbstractThis chapter gives an overview of molecules and mechanisms able to intervene with the biological effects of ionizing radiation (IR), either related to their clinical use in radiotherapy or in the field of radiation protection in case of an accidental exposure to radiation and/or nuclear emergencies. According to the National Cancer Institute, “radiomodifiers” can be classified into (a) radioprotectors (protect molecules and tissues from direct and indirect damage induced by IR) or (b) radiomitigators (reduce and help to repair damage), depending on whether they are administered pre- or post-IR exposure, respectively. Most of them are free radical scavengers and antioxidants (or enhancers of the antioxidant defenses), increase DNA repair mechanisms, have anti-inflammatory properties, and/or prevent cell death. On the other hand, (c) radiosensitizers directly or indirectly enhance DNA damage and ROS production, increasing IR toxicity on tumor cells, thus they are used to increase radiotherapy efficacy in cancer patients. The section “Radionuclides and methods to treat contaminated individuals” describes the medical consequences and treatment modalities of internal contamination by radionuclides. Overall, the chapter discusses the effects of most currently known radiomodifiers, their specific properties, and their mechanisms of action, by emphasizing results obtained in recent preclinical and clinical trials.
Molecular Radiation Biology
Authors: Reindl Judith , Abrantes Ana Margarida , Ahire Vidhula , Azimzadeh Omid , Baatout Sarah , Baeyens Ans , Baselet Bjorn , Chauhan Vinita , Da Pieve Fabiana , Delbart Wendy , Dobney Caitlin Pria , Edin Nina Frederike Jeppesen , Falk Martin , Foray Nicolas , François Agnès , Frelon Sandrine , Gaipl Udo S. , Georgakilas Alexandros G. , Guipaud Olivier , Hausmann Michael , Michaelidesova Anna Jelinek , Kadhim Munira , Marques Inês Alexandra , Milic Mirta , Mistry Dhruti , Moertl Simone , Montoro Alegría , Obrador Elena , Pires Ana Salomé , Quintens Roel , Rajan Nicholas , Rödel Franz , Rogan Peter , Savu Diana , Schettino Giuseppe , Tabury Kevin , Terzoudi Georgia I. , Triantopoulou Sotiria , Viktorsson Kristina , Wozny Anne-Sophie 
Published: September 2023

AbstractVarious exogeneous and endogenous factors constantly cause damages in the biomolecules within a cell. For example, per day, 10,000–100,000 molecular lesions occur in DNA per cell. The molecule modifications that are formed disturb the structure and function of the affected molecules. The purpose of this chapter is to introduce the damages to biomolecules caused by radiation, the associated repair pathways, and the effect on the cellular function. Special interest lies on the damages induced to DNA, the carrier of the human genome, and the consequence to genomic integrity, cell death, and cell survival. Additionally, related effects regarding inflammation and immunity, epigenetic factors, and omics are discussed. The chapter concludes with an explanation of the molecular factors of cellular hyper-radiosensitivity and induced radiation resistance.
Clinical Radiobiology for Radiation Oncology
Authors: Sminia Peter , Guipaud Olivier , Viktorsson Kristina , Ahire Vidhula , Baatout Sarah , Boterberg Tom , Cizkova Jana , Dostál Marek , Fernandez-Palomo Cristian , Filipova Alzbeta , François Agnès , Geiger Mallia , Hunter Alistair , Jassim Hussam , Edin Nina Frederike Jeppesen , Jordan Karl , Koniarová Irena , Selvaraj Vinodh Kumar , Meade Aidan D. , Milliat Fabien , Montoro Alegría , Politis Constantinus , Savu Diana , Sémont Alexandra , Tichy Ales , Válek Vlastimil , Vogin Guillaume 
Published: September 2023

AbstractThis chapter is focused on radiobiological aspects at the molecular, cellular, and tissue level which are relevant for the clinical use of ionizing radiation (IR) in cancer therapy. For radiation oncology, it is critical to find a balance, i.e., the therapeutic window, between the probability of tumor control and the probability of side effects caused by radiation injury to the healthy tissues and organs. An overview is given about modern precision radiotherapy (RT) techniques, which allow optimal sparing of healthy tissues. Biological factors determining the width of the therapeutic window are explained. The role of the six typical radiobiological phenomena determining the response of both malignant and normal tissues in the clinic, the 6R’s, which are Reoxygenation, Redistribution, Repopulation, Repair, Radiosensitivity, and Reactivation of the immune system, is discussed. Information is provided on tumor characteristics, for example, tumor type, growth kinetics, hypoxia, aberrant molecular signaling pathways, cancer stem cells and their impact on the response to RT. The role of the tumor microenvironment and microbiota is described and the effects of radiation on the immune system including the abscopal effect phenomenon are outlined. A summary is given on tumor diagnosis, response prediction via biomarkers, genetics, and radiomics, and ways to selectively enhance the RT response in tumors. Furthermore, we describe acute and late normal tissue reactions following exposure to radiation: cellular aspects, tissue kinetics, latency periods, permanent or transient injury, and histopathology. Details are also given on the differential effect on tumor and late responding healthy tissues following fractionated and low dose rate irradiation as well as the effect of whole-body exposure.