bluuebunny/crossref_metadata_2025_split huggingface dataset:
Test–retest reliability of electroencephalographic and magnetoencephalographic measures elicited during language tasks: A literature review
Authors: Cocquyt Elissa‐Marie , Van Laeken Heleen , van Mierlo Pieter , De Letter Miet 
Published: March 2023

AbstractElectroencephalographic (EEG) and magnetoencephalographic (MEG) recordings during language processing can provide relevant insights on neuroplasticity in clinical populations (including patients with aphasia). To use EEG and MEG in a longitudinal way, the outcome measures should be consistent across time in healthy individuals. Therefore, the current study provides a review on the test–retest reliability of EEG and MEG measures elicited during language paradigms in healthy adults. PubMed, Web of Science and Embase were searched for relevant articles based on specific eligibility criteria. In total, 11 articles were included in this literature review. The test–retest reliability of the P1, N1 and P2 is systematically considered to be satisfactory, whereas findings are more variable for event‐related potentials/fields occurring later in time. The within subject consistency of EEG and MEG measures during language processing can be influenced by multiple variables such as the stimulus presentation mode, the offline reference choice and the required amount of cognitive resources during the task. To conclude, most of the available results are favourable regarding the longitudinal use of EEG and MEG measures elicited during language paradigms in healthy young individuals. In view to the use of these techniques in patients with aphasia, future research should focus on whether the same findings apply to different age groups.
Human nature, history, and the limits of critique
Authors: Setiya Kieran 
Published: March 2023

AbstractThis essay defends a form of ethical naturalism in which ethical knowledge is explained by human nature. Human nature, here, is not the essence of the species but its natural history as socially and historically determined. The argument does not lead to social relativism, but it does place limits on the scope of ethical critique. As society becomes “total”, critique can only be immanent; to this extent, Adorno and the Frankfurt School are right.
Transcriptomic and proteomic studies suggest the establishment of advanced zonation‐like profiles in human‐induced pluripotent stem cell‐derived liver sinusoidal endothelial cells and carboxypeptidase M‐positive liver progenitor cells cocultured in a fluidic microenvironment
Authors: Danoy Mathieu , Poulain Stéphane , Jellali Rachid , Scheidecker Benedikt , Tauran Yannick , Leduc Marjorie , Bruce Johanna , Kim Soo Hyeon , Kido Taketomo , Miyajima Atsushi , Sakai Yasuyuki , Leclerc Eric 
Published: March 2023

AbstractAimHepatic zonation is a physiological feature of the liver, known to be key in the regulation of the metabolism of nutrients and xenobiotics and the biotransformation of numerous substances. However, the reproduction of this phenomenon remains challenging in vitro as only part of the processes involved in the orchestration and maintenance of zonation are fully understood. The recent advances in organ‐on‐chip technologies, which allow for the integration of multicellular 3D tissues in a dynamic microenvironment, could offer solutions for the reproduction of zonation within a single culture vessel.MethodsAn in‐depth analysis of zonation‐related mechanisms observed during the coculture of human‐induced pluripotent stem cell (hiPSC)‐derived carboxypeptidase M‐positive liver progenitor cells and hiPSC‐derived liver sinusoidal endothelial cells within a microfluidic biochip was carried out.ResultsHepatic phenotypes were confirmed in terms of albumin secretion, glycogen storage, CYP450 activity, and expression of specific endothelial markers such as PECAM1, RAB5A, and CD109. Further characterization of the patterns observed in the comparison of the transcription factor motif activities, the transcriptomic signature, and the proteomic profile expressed at the inlet and the outlet of the microfluidic biochip confirmed the presence of zonation‐like phenomena within the biochips. In particular, differences related to Wnt/β‐catenin, transforming growth factor‐β, mammalian target of rapamycin, hypoxia‐inducible factor‐1, and AMP‐activated protein kinase signaling, to the metabolism of lipids, and cellular remolding were observed.ConclusionsThe present study shows the interest in combining cocultures of hiPSC‐derived cellular models and microfluidic technologies for reproducing in vitro complex mechanisms such as liver zonation and further incites the use of those solutions for accurate reproduction of in vivo situations.
Decisions about adopting novel COVID‐19 vaccines among White adults in a rural state, USA: A qualitative study
Authors: Kohut Mike , Scharnetzki Liz , Pajka Joseph , Jacobs Elizabeth A. , Fairfield Kathleen M. 
Published: March 2023

AbstractPurposeMany people, especially in rural areas of the United States, choose not to receive novel COVID‐19 vaccinations despite public health recommendations. Understanding how people describe decisions to get vaccinated or not may help to address hesitancy.MethodsWe conducted semistructured interviews with 17 rural inhabitants of Maine, a sparsely populated state in the northeastern US, about COVID‐19 vaccine decisions during the early rollout (March–May 2021). We used the framework method to compare responses, including between vaccine Adopters and Non‐adopters.FindingsAdopters framed COVID‐19 as unequivocally dangerous, if not personally, then to other people. Describing their COVID concerns, Adopters emphasized disease morbidities. By contrast, Non‐adopters never mentioned morbidities, referencing instead mortality risk, which they perceived as minimal. Instead of risks associated with the disease, Non‐adopters emphasized risks associated with vaccination. Uncertainty about the vaccine development process, augmented by social media, bolstered concerns about the long‐term unknown risks of vaccines. Vaccine Adopters ultimately described trusting the process, while Non‐adopters expressed distrust.ConclusionMany respondents framed their COVID vaccination decision by comparing the risks between the disease and the vaccine. Associating morbidity risks with COVID‐19 diminishes the relevance of vaccine risks, whereas focusing on low perceived mortality risks heightens their relevance. Results could inform efforts to address COVID‐19 vaccine hesitancy in the rural US and elsewhere.Patient or Public ContributionMembers of Maine rural communities were involved throughout the study. Leaders of community health groups provided feedback on the study design, were actively involved in recruitment, and reviewed findings after analysis. All data produced and used in this study were co‐constructed through the participation of community members with lived experience.
Talking Trials: An arts‐based exploration of attitudes to clinical trials amongst minority ethnic members of the South Riverside Community of Cardiff
Authors: Bridges Sarah , Lamont‐Robinson Catherine , Herbert Allan , Din Mashmooma , Smith Carl , Ahmed Nasra , Ali Arafa , Bandyopadhyay Sudipta , Bibi Saleema , Canu Rossana , Correia Mariama N. G. , Djalo Mamadu S. , Hayan Kense , Horne Alka , Mita Ayesha , Svobodova Martina 
Published: March 2023

AbstractIntroductionClinical trials must include diverse participants to ensure the wide applicability of results. However, people from ethnic minorities are included in clinical trials at rates lower than expected given their share of the population. Working with South Riverside Community Development Centre (SRCDC), Talking Trials used public engagement to foster discussions around the underrepresentation of those from minority ethnic communities in clinical trials and to identify and address concerns surrounding trial participation.MethodsWe conducted three workshops with 13 co‐researchers from minority ethnic backgrounds. We explored perceptions and understanding of clinical trials alongside participatory art activities to help move away from verbocentric methods of communication. These artworks formed an exhibition that was presented to the community, prompting further discussions and engagement.FindingsCo‐production workshops were an effective tool to introduce the public to trial research. With little knowledge of clinical trials at the beginning of the process, our co‐researchers formed a cohesive group, sharing initial fears and mistrust towards trials. As conversations progressed these attitudes clearly shifted. Artwork produced during the workshops was incorporated into an exhibition. Quotes and creative pieces from the group were included to reflect the themes identified. Presenting the exhibition at Riverside Festival enabled further engagement with a wider diverse community. The focus on co‐production helped build a network of individuals new to research and keen to become involved further.ConclusionInclusive and democratic co‐production, enriched by participatory art practices, provided a powerful means of enabling our group to create new insights and foster new relationships. Projects like Talking Trials can diversify the research process itself—for example, four co‐researchers have commenced lay research partner roles on trial management groups and a lay advisory group is in development.Patient or Public ContributionThree members of staff at SRCDC were on the project delivery group and involved in the initial project design, subsequently helping to connect us with members of the Riverside community to work as co‐researchers. Two of the SRCDC staff are co‐authors of this manuscript. The project had 13 public co‐researchers guiding the direction of this research and creating the artwork displayed in the art exhibition.
Child health nursing in the Solomon Islands: A qualitative evaluation of the impact of the ‘Bachelor of nursing ‐ Child health’
Authors: Burhin M. , Isom V. , Ogaoga D. , Devine S. , Duke T. , Bugoro H. , Tamou M. , Mark C. , Panda N. 
Published: March 2023

AbstractAimTo explore graduates’ perceptions of the impact on nursing practice of a new postgraduate course in child health, developed and implemented in the Solomon Islands in 2016.BackgroundThe Bachelor of Nursing ‐ Child Health was implemented in 2016 to develop nurses’ knowledge and skills in child health and paediatric care with the intent to improve national child health outcomes.DesignA qualitative exploratory, descriptive design was used to evaluate the impact of the Bachelor of Nursing ‐ Child Health on graduates’ nursing practice.MethodsFourteen nurses who graduated from the first cohort of students enrolled in the child health course were purposively selected to participate. Participants engaged in individual semi‐structured interviews, conducted between August and December 2018. A thematic analysis was undertaken following Braun and Clarke's six‐phase process.ResultsFindings from the study demonstrate positive impacts of the course on graduates’ nursing practice. These include a perceived enhanced quality of care through their commitment to evidence‐based practice, the ability to contribute to capacity building of colleagues, the reinforcement of provincial public health programmes and expanded participation in managerial activities. Following graduation, most alumni took on senior roles and greater responsibilities, felt more confident in managing unwell children, felt there was better access to and quality of child health care at the community and broader country levels and felt recognised by colleagues and communities. Some graduates faced resistance from colleagues to change practice and felt that despite being given greater responsibilities, nursing levels and salaries remained unchanged. This reflected a potential lack of recognition from hospital or provincial managers, the Nursing Council as the regulatory body for the nursing profession, and the Ministry of Health and Medical Services. A lack of human and material resources also impacted quality of care.Implications for Nursing and Health PolicyFindings from this study underline the need for the Solomon Islands National University, the Nursing Council, the Public Service and the Ministry of Health and Medical Services to concord and delineate formal accreditation standards for child health nurses. Overall, collaborative efforts and commitments at local, regional and global levels are required to support child health nurses in their ability and ambition to improve national child health outcomes.ConclusionsFindings from this study demonstrate positive impacts of the course on graduates’ nursing practice. The impact of increasing nurses’ knowledge and skills on national child health outcomes could be significant. Ongoing implementation and recognition of this course in the Solomon Islands, as well as more broadly across the Pacific region, are recommended.
Texas Cowboy Boots: America's Material Culture Melting Pot
Authors: Loranger David , Divita Lorynn 
Published: March 2023

AbstractCowboy boots are some of the most recognizable dress icons in the United States and symbolize the American West. The mythology of these material culture objects has been built over hundreds of years in many types of oral and written narratives. The purpose of this study was to combine secondary sources focusing on specific dimensions of cowboy boots with interviews of bootmakers and firm owners, developing a clearer understanding of the multicultural evolution of this material culture icon. Results indicate that although most bootmakers are aware of the multicultural origins of cowboy boots, they do not possess a complete comprehension of the origins and development of this material culture icon.
Factor analysis of evaluated and linearly scored traits in Swedish Warmblood horses
Authors: Nazari‐Ghadikolaei Anahit , Fikse Freddy , Gelinder Viklund Åsa , Eriksson Susanne 
Published: March 2023

AbstractAssessment protocols to describe the various aspects of conformation, gait and jumping traits on a linear scale were introduced at young horse tests for Swedish Warmblood horses in 2013. The traits scored on a linear scale are assumed to be less subjective and more easily compared across populations than the traditional evaluated traits that are scored relative to the breeding goal. However, the resulting number of traits is considerable, and several of the traits are correlated. The aim of this study was to investigate the interrelationship between the different evaluated and linearly scored traits in Swedish Warmbloods using factor analysis. In total, 20,935 horses born 1996–2017 had information on evaluated traits, and 5450 of these also had linearly scored trait records assessed since 2014 when the protocol was updated. A factor analysis with varimax rotation was performed separately for evaluated and linearly scored traits using the Psych package in R. Height at withers was included in both analyses. A total of four factors for evaluated traits and 14 factors for linearly scored traits were kept for further analysis. Missing values for individual traits in horses with linearly scored trait records were imputed based on correlated traits before factor scores were calculated using factor loadings. Genetic parameters for, and correlations between, the resulting underlying factors were estimated using multiple‐trait animal models in the BLUPF90 package. Heritability estimates were on a similar level as for the traits currently used in the genetic evaluation, ranging from 0.05 for the factor for linearly scored traits named L.behaviour (dominated by traits related to behaviour) to 0.59 for the factor for evaluated traits named E.size (dominated by height at withers and conformation). For both types of traits, separate factors were formed for jumping and gait traits, as well as for body size. High genetic correlations were estimated between such corresponding factors for evaluated traits and factors for linearly scored traits. In conclusion, factor analysis could be used to reduce the number of traits to be included in multiple‐trait genetic evaluation or in genomic analysis for warmblood horses. It can also contribute to a better understanding of the interrelationships among the assessed traits and be useful to decide on subgroups of traits to be used in several multiple‐trait evaluations on groups of original traits.
Developing a consensus to support health and social care professionals and patients manage nutrition in the context of COVID‐19 recovery
Authors: Tronco Hernandez Yessica Abigail , Julian Anna , Weekes Elizabeth C. , Murphy Jane , Frost Gary , Hickson Mary 
Published: March 2023

AbstractBackgroundThe long‐term effects on people who have had COVID‐19 affect nutrition and can be influenced by diet conversely. Specific nutritional guidelines, however, were scarce at the beginning of 2020, and empirical literature was also lacking. Conventional research methodologies needed to be adapted to review the available literature that could be relevant to the United Kingdom and policy documents as well as collect the views of health and care staff. The aim of this paper is to describe the method to develop consensus statements from experts to address the necessary nutritional support and what emerged from this.MethodsA nominal group technique (NGT) was adapted to the virtual world; we purposefully selected a range of professionals (dietitians, nurses, occupational therapists, etc.) and patients with long‐term effects of COVID to present them with the most updated evidence and aim to reach key guidelines to address COVID‐19 recovery.ResultsWe were able to reach consensus statements that were developed and reviewed by relevant healthcare staff at the front line to address the nutritional needs of patients recovering from COVID‐19 and those suffering from its long‐term effects. This adapted NGT process led us to understand that a virtual repository of concise guidelines and recommendations was needed. This was developed to be freely accessed by both patients recovering from COVID‐19 and health professionals who manage them.ConclusionsWe successfully obtained key consensus statements from the adapted NGT, which showed the need for the nutrition and COVID‐19 knowledge hub. This hub has been developed, updated, reviewed, endorsed and improved across the subsequent 2 years.
Gastrointestinal angiodysplasias diagnosed using video capsule endoscopy in 15 dogs
Authors: Defarges Alice , Stiller Jenny , Solomon Jeffrey A. 
Published: March 2023

AbstractBackgroundAngiodysplasia (AGD) is rarely diagnosed in dogs with gastrointestinal bleeding (GIB) and is reported in case reports in dogs.ObjectiveDescribe signalment, clinical and diagnostic features of dogs with gastrointestinal (GI) AGD diagnosed by video capsule endoscopy (VCE).AnimalsDogs with overt or suspected GIB which underwent VCE.MethodsDogs for which a VCE was submitted for overt or suspected GIB from 2016 to 2021 were selected retrospectively. Medical records and full‐length VCE recordings where AGDs were initially detected, were reviewed by 2 trained internists. AGD was considered definitive if 2 readers detected it. Signalment, clinical signs, blood work, medications, concurrent diseases, findings of previous conventional endoscopy, and surgical exploration (if applicable) of dogs with AGD were recorded.ResultsDefinitive AGD was diagnosed in 15 of 291 (5%) dogs (12 males, 3 females). Twelve (80%) had overt GIB, 11 (73%) had hematochezia, and 6 (40%) had microcytic and hypochromic anemia. AGD was missed by conventional endoscopy in 9/9 dogs and exploratory surgery in 3/3 dogs. Thirteen capsules were administered by mouth (1 incomplete study), and 2 via endoscopy directly into the duodenum. AGD was visualized in the stomach of 3 dogs, in the small intestine of 4, and in the colon of 13 dogs.Conclusion and Clinical ImportanceAlthough rare, AGD should be considered in dogs with suspected GIB after a negative conventional endoscopy or surgical exporation. Video capsuel endoscopy appears to be a sensitive test to identify AGD within the GI tract.
Turkey's Hydropolitics: Building Order in the Middle East
Authors: Hamidi Somaye , Mozdkhah Ehsan 
Published: March 2023

AbstractWater resources have evolved into a major tool for expanding a country's regional influence. The dynamic interactions of hydraulics strategies have thus been regarded as critical factors in Middle Eastern politics. As Turkey controls upstream water resources in the region, this study attempts to answer this question: What goals does Turkey pursue with its water‐control policy? The article demonstrates that Turkey is seeking to become the dominant power in the Middle East by regulating hydropolitics.
Supporting older people following out of hours discharge from the Emergency Department: An integrative review of the literature
Authors: Dunnion Mary , Ryan Assumpta , Goode Debbie , McIlfatrick Sonja 
Published: March 2023

AbstractBackgroundFor many older people the emergency department (ED) is an important but sometimes difficult step in their healthcare journey. They often attend the ED with co and multi morbidities. Discharge home at evenings and weekends when post‐discharge support services are limited can result in a delay or failure to follow through on their discharge plan leading to adverse health outcomes and in some cases, readmission to ED.ObjectiveThe aim of this integrative review was to identify and appraise the support available to older people following discharge from the ED out of hours (OOH).MethodsFor this review, out of hours referred to those times after 17.30 until 08.00 a.m. on Mondays to Fridays, all hours on weekends and public holidays. Whittemore and Knafl's (Journal of Advanced Nursing, 2005;52:546), framework was used to guide all stages of the review process. Articles were retrieved following a rigorous search of published works using various databases, the grey literature and hand search of the reference lists of the studies included.ResultsIn total 31 articles were included in the review. These comprised systematic reviews, randomised control studies, cohort studies and surveys. Main themes identified included processes that enable support, support provision by health and social care professionals and telephone follow‐up. Results identified a significant dearth of out of hours discharge research and a strong recommendation for more concise and thorough research in this important area of care transition.ConclusionOlder person discharge home from the ED presents an associated risk as previous research has identified frequent readmission and periods of ill health and dependency. Out of hours discharge can be even more problematic when it may be difficult to arrange support services and ensure continuity of care. Further work in this area is required, taking cognisance of the findings and recommendations identified in this review.