bluuebunny/crossref_metadata_2025_split huggingface dataset:
Accumulation of chemical elements in the roots of <I>Euphorbia fischeriana</I> Steudel in the Shilka river basin (Transbaikal region)
Authors: Makarov V. P. 
Published: December 2022

Background. Euphorbia fischeriana Steudel is used in traditional and herbal medicine in Russia and China. Its roots contain 241 chemical components, but there is not enough knowledge about the plant’s elemental composition. Concentrations of chemical elements in plants have an impact the effectiveness of medical products.Materials and methods. The research was conducted in the Transbaikal region. Plants were analyzed using an ICP-MS Elan 9000 mass spectrometer (Canada). The ICP-MS method of measuring metal content in solid objects, PND F 16.1:2.3:3.11-98 was used. Chemical analysis of the soil was performed at Kostromskaya State Station of Agrochemical Service. The obtained data were statistically processed using the Microsoft Excel software.Results. The accumulation of macro- and microelements in plant roots was studied (Ca, P, Mg, Na, Fe, Mn, Zn, Mo, Cr, Co, Se, Cu, B, Ni, V, As, Li, Pb, Ba, Bi, Cd, Hg, Be, Sb, Rb, Zr, Sn, Ag, W, Sr, and Ti). The chemical elements whose concentrations were significantly higher or, contrariwise, lower than the clarke of terrestrial plants were identified. Accumulations of Ti, Ag, As, Cr, Sr, Li, Ba, Mo, Fe, Bi, and Sb in descending order were 2–14 times higher than the clarke of terrestrial plants. Concentrations of Mn, Cd, Se, and especially V and Cu in E. fischeriana roots were low (0.01–5% of the clarke). The concentration of As in the test areas exceeded the threshold limit value for medicinal herbage and medicinal plant products (OFS.1.5.3.0009.15). Conclusion. The study made it possible to find deficiencies of a number of vital elements in E. fischeriana roots, discrepancy between the tested herbage and the threshold limit value for As, and increased accumulation of a number of toxic and potentially toxic elements compared with the clarke.
Promising source material for winter triticale breeding under the conditions of the Middle Urals
Authors: Potapova G. N. , Zobnina N. L. , Bezgodov A. V. , Ivanova M. S. 
Published: December 2022

Background. The northern border of cereal crop cultivation passes through the territory of Sverdlovsk Province. Cultivars of winter triticale developed in the regions of Russia located to the south are grown there, but they die under unfavorable winter conditions. The breeding of this crop in local climate is at an early stage, so a study of source material for breeding new highyielding cultivars adapted to local conditions seems quite pertinent.Materials and methods. In 2017–2020, the Ural Research Institute of Agriculture in Yekaterinburg conducted a study of 78 winter triticale genotypes from 10 regions of Russia and 7 foreign countries. The seeds were obtained from the VIR genebank and breeding centers of Russia. Sowing was carried out in clean fallow on August 20–25 on 1 m2 plots in 3-4 repetitions, with the reference ‘Bashkirskaya korotkostebelnaya’ sown on every 10th plot. Plants were assessed for winter hardiness, yield, density of productive stems, plant height, ear length, number of spikelets and grains per ear, weight of 1000 grains, and ear productivity in accordance with published guidelines.Results. Cvs. ‘Privada’, ‘Tsekad 90’ and ‘Nemchinovsky 58’ combined high winter hardiness (70–81%) with resistance to damage by snow mold (15–20%), high density of productive stems (324–425 pcs/m2), and high yield (562–616 g/m2). They had high 1000 grain weight (45.4–49.1 g) and ear productivity (2.63–2.68 g). High yield (571–670 g/m2) and density of productive stems (285–436 pcs/m2 ) with reduced winter hardiness (62–72%) and resistance to snow mold (30–35%) was observed in cvs. ‘Sirs 57’, ‘Sotnik’, ‘Germes’, ‘Antey’, ‘Beta’, ‘Don’, and lines 1/1 and 8003 from Sweden.
Optimal levothyroxine dose to achieve euthyroidism in patients with primary hypothyroidism: analysis according to etiology
Authors: Ramírez Stieben Luis Agustín , Pustilnik Estefanía , Feldman Rodolfo , Paladini Luciana , Mancinelli Laura , Pellizzón Noelia Andrea , Schwarzstein Diego 
Published: December 2022

Introduction. Levothyroxine (LT4) has been considered the standard of care for treatment of hypothyroidism. Current recommendations suggest a LT4 dose between 1.6–1.8 µg/kg/day. The aim of this study was to evaluate the LT4 dose for adult patients with primary hypothyroidism of different etiologies who reached euthyroidism.
Methods. A cross-sectional study was performed from the retrospective review of the charts of patients with primary hypothyroidism in treatment with LT4. Subjects were classified according to TSH level in overtreated (TSH < 0.4 µIU/ml), euthyroid (TSH 0.40-4.20), and undertreated (TSH >4.2) and according to the etiology of hypothyroidism. A stepwise logistic regression model was performed to evaluate the variables associated with TSH<0.4 µIU/ml.
Results. 955 patients were included. 75.13% of the patients had an adequate LT4 replacement. LT4 dose to achieve euthyroidism was higher in patients with a history of radioiodine therapy (1.92 μg/kg) and thyroid surgery (1.52 μg/kg), while the LT4 dose required to achieve euthyroidism in patients with Hashimoto's thyroiditis and atrophic thyroiditis was lower than that reported in previous studies (1.25 and 1.08 μg/kg, respectively). The variables that were associated with a higher probability of TSH<0.4 µIU/ml were male gender, Hashimoto's thyroiditis, radioiodine therapy, and thyroid surgery.
Major conclusion. LT4 dose required to achieve euthyroidism in patients with hypothyroidism varies according to the etiology, being higher in patients with hypothyroidism due to radioiodine therapy and thyroid surgery. Patients with hypothyroidism due to Hashimoto's thyroiditis and atrophic thyroiditis require a lower dose than current recommendations.
Perancangan Sistem Absensi Care Group Mahasiswa Berbasis Web Menggunakan Metode Agile Development (Studi Kasus: Universitas Advent Indonesia)
Authors: Panjaitan Jeremy , Pakpahan Andrew 
Published: December 2022

Universitas advent Indonesia (UNAI) merupakan sebuah universitas berasrama dimana mahasiswa/i yang berkuliah pada universitas ini tinggal di dalam asrama yang telah di sediakan. Walaupun begitu, unai memberikan kebebasan kepada mahasiswa/i untuk memilih tinggal di asrama (inside) atau di luar asrama (outside). Dalam mendidik unai mengedepankan pengembangan karakter. Untuk itu, unai memberikan beberapa peraturan yang perlu diikuti. Salah satu peraturan yang perlu diikuti oleh mahasiswa adalah mengikuti Caregroup. Caregroup merupakan kelompok doa yang beranggotakan beberapa mahasiswa/i, ketua caregroup. yang mendampingi kelompok doa tersebut. Setiap semester unai melakukan caregroup dimana ketua caregroup yang bertugas akan mengambil absensi dari setiap mahasiswa/i. Pengambilan absensi ini masih dilakukan secara manual. Staff unai akan membagikan form absensi ke setiap ketua caregroup. Setelah itu ketua caregroup akan mengabsensi setiap mahasiswa/I dengan meminta mereka memberikan tanda tangan mereka sebagai tanda bahwa mereka menghadiri caregroup. Namun terdapat beberapa mahasiswa/i yang menandatangani mahasiswa/i lainnya sehingga data absen menjadi tidak akurat. Masalah lain yang muncul yaitu proses rekapitulasi absensi mahasiswa/i membutuhkan waktu yang cukup lama. Untuk itu dirancang sebuah sistem informasi absensi untuk memudahkan proses absensi mahasiswa/i pada saat caregroup dilakukan sehingga peraturan yang telah ditetapkan oleh UNAI dapat berjalan dengan baik. Metode yang digunakan dalam perancangan system ini adalah agile software development dimana dengan metode tersebut memungkingkan dilakukan perancangan terhadap sistem dengan waktu yang singkat. Hasil dari penelitian ini adalah sebuah rancanga dari sistem absensi caregroup didalamnya terdapat usecase diagram dimana terdapat dua actor utama yaitu ketua caregroup dan admin; class diagram; dan rancangan interface dari system ini
Effect of Ranibizumab and Aflibercept on Retinal Pigment Epithelial Detachment, Subretinal, and Intra-Retinal Fluid in Age-Related Macular Degeneration
Authors: Sumarová Patrícia , Ovesná Petra , Matoušková Veronika , Beránek Jan , Michalec Marek , Michalcová Lenka , Autrata Daniel , Vysloužilová Daniela , Chrapek Oldřich 
Published: December 2022

Purpose: The aim of the study was to compare the effect of three initial doses of the anti-VEGF ranibizumab and aflibercept medication on serous pigment epithelial detachment (PED), subretinal fluid (SRF) and intraretinal fluid (IRF) in the macula of treatment naive neovascular AMD (nvAMD) patients.
Material and Methods: The cohort consists of 148 patients, of which 74 patients were treated with ranibizumab (51 females and 23 males) and 74 with aflibercept (46 females and 28 males). The data was recorded prospectively from the moment of diagnosis and start of treatment for a period of 3 months. At the moment of diagnosis and 3 months later, an OCT examination (Spectralis OCT, Heidelberg Engineering, Heidelberg, Germany) was performed. The OCT examination included a macular scan with 25 scans. Using the OCT instrument software, we measured the maximum anterior-posterior elevation of serous PED, the highest thickness of SRF and the largest diameter of the intraretinal cystic space. The statistical significance of differences between groups was evaluated using the t-test for continuous data and the Fisher exact test for categorical data. Changes in values of continuous variables over time were evaluated using the Wilcoxon paired test. Paired comparisons of binary parameters were determined by the McNemar test.
Results: Full regression of PED, SRF and IRF occurred in 3 (4.1%), 25 (39%) and 20 (51%) patients treated with ranibizumab, and in 5 (7.9%, p = 0.470),
28 (47%, p = 0.470) and 25 (57%, p = 0.827) patients treated with aflibercept, respectively. The average regression of PED, SRF and IRF was -60.4 µm (median -37.5 µm), -84.3 µm (median -85 µm) and -109.3 µm (median -81 µm) in patients treated with ranibizumab, and -46.3 µm (median -30 µm, p = 0.389), -127.7 µm (median -104 µm, p = 0.096) and -204.4 µm (median -163 µm, p = 0.005) in patients treated with aflibercept, respectively. We did not show a statistically significant difference in the regression rates of PED, SRF and IRF between the ranibizumab and aflibercept groups. (in patients with IRF after adjustment of the higher baseline IRF volumes in patients treated with aflibercept, p = 0.891).
Conclusion: We are convinced that ranibizumab and aflibercept have the same effect on serous PED, SRF and IRF in the macula in patients with treatment naive nvAMD during the initial loading phase.
Szanse i zagrożenia dla administracji publicznej w świadczeniu usług drogą elektroniczną
Authors: Romaniuk Paweł 
Published: December 2022

Współczesna realizacja usług drogą elektroniczną w administracji publicznej, jest jedną z form załatwiania spraw urzędowych. Przyjęte podstawy prawne w zakresie świadczenia elektronicznych usług, zapewniają widoczną dynamikę rozwoju nowoczesnych technologii informacyjno-komunikacyjnych. Takie rozwiązania wymagają nieustannych zmian legislacyjnych. Przyjęcie przez ustawodawcę modelu delegacji ustawowych do regulowania poszczególnych tematów, silnie powiązanych ze świadczeniem elektronicznych usług, zapewnia dostosowanie tych przepisów do bardzo szybko zmieniającego się otoczenia technologicznego. Celem artykułu jest wskazanie, że pojawiające się możliwości w zakresie rozwoju tej sfery życia publicznego, niewątpliwie napotykają także na różnorodne problemy i bariery. Niniejszy artykuł przybliża aspekty związane z rozwojem elektronicznej administracji, wskazując zarówno na szanse, jak i zagrożenia, pojawiające się w codziennym funkcjonowaniu administracji publicznej. Autor wskazuje również założenia de lege ferenda, których nadrzędnym celem jest wskazanie istotności funkcjonującego systemu, wykorzystującego model elektronicznych usług, wdrażanych na wszystkich poziomach administracji publicznej.
Kryminalistyczne aspekty wykrywania sprawców przestępstw gospodarczych
Authors: Juszka Kazimiera 
Published: December 2022

Ważnym czynnikiem ochrony prowadzenia działalności gospodarczej jest ciągłe podejmowanie działań organów procesowych prowadzących postępowania karne w celu wykrycia sprawców przestępstw gospodarczych. W codziennej pracy organów postępowania pomocne jest uwzględnianie czynników wpływających na efektywność procesu wykrywczego. W przedmiotowym artykule przedstawiono następujące czynniki: wersja kryminalistyczna oraz przeprowedzanie oględzin w wykrywaniu sprawców przestępstw gospodarczych. Celem artykułu jest analiza kryminalistycznych aspektów przestępczości gospodarczej z punktu widzenia czynności organów prowadzących postępowanie karne. Przedmiotowa prezentacja zostanie przedstawiona za pomocą czynników wpływających na efektywność prowadzenia postępowań karnych w celu wykrycia sprawców przestępstw gospodarczych tj. wersji kryminalistycznej oraz oględzin w wykrywaniu sprawców przestępstw gospodarczych. Niniejsze czynniki należy rozumieć jako każda aktywność organów postępowania w przedmiocie wykrycia sprawców przestępstw gospodarczych, mająca wpływ na efektywność dalszego prowadzenia postepowania karnego oraz kształt prawomocnego wyroku. Przedstawiona w niniejszym artykule analiza wersji kryminalistycznej oraz oględzin w wykrywaniu sprawców przestępstw gospodarczych stanowi najdonioślejsze aspekty ich wykrywania zarówno pod względem doktrynalnym ja również utylitarnym. Nieprawidłowe i nieefektywne przeprowadzenie oględzin a także nieprzestrzeganie zasad budowy wersji kryminalistycznych bezpośrednio wpływa na trudności dowodowe mogące uniemożliwić wykrycie sprawcy tytułowych przestępstw w toku postępowania karnego.
Biblical Hexameron as the Gospel
Authors: Олег Мумриков, 
Published: December 2022

Библейский Шестоднев в настоящее время часто воспринимается исключительно как космогонический текст, что неизбежно порождает попытки его интерпретаций лишь в контексте современной естественнонаучной картины мира (что само по себе неверно, поскольку научные картины мира находятся в постоянном динамичном развитии). Поэтому для библейской апологетики представляется перспективным, не отрицая историчности повествования первой главы Книги Бытия, рассматривать её в первую очередь как особый гимн-благовестие в контексте всего корпуса книг Священного Писания Ветхого и Нового Заветов. Автор попытался показать, что данный вполне традиционный церковный подход к осмыслению первой главы Книги Бытия позволяет избежать не только последствий допущения искусственных упрощений, неизбежных при построении моделей конкорданса библейских текстов и естественнонаучных данных, но и ошибок интерпретации Шестоднева как «случайного», «устаревшего» или «лишнего» фрагмента Книги Бытия.
Biblical Hexameron is now often perceived exclusively as a cosmogonic text, which inevitably gives rise to attempts to interpret it only in the context of the modern natural-scientific picture of the world (which in itself is not true, since the scientific pictures of the world are in constant dynamic development). Therefore, for biblical apologetics, it seems promising, without denying the historicity of the narration of the first chapter of the Book of Genesis, to consider it primarily as a special hymn-evangelism in the context of the entire corpus of the Holy Scriptures of the Old and New Testaments. The author tried to show that this quite traditional Church approach to comprehending the first chapter of Genesis allows avoiding not only the consequences of making artificial simplifications, which are inevitable in the construction of models of the concordance of biblical texts and natural science data, but also errors of interpreting Hexameron as «accidental», «outdated» or «extra» fragment of the Book of Genesis.
The Doctrine of the Judgment of God over the Gentiles in the Epistle of St. Paul the Apostle to the Romans (Romans 1, 18-32): An Attempt of Theologicaland Exegetical Commentary
Authors: Михаил Всеволодович Ковшов, , Михаил Еремин, , Александр Тодиев, 
Published: December 2022

Статья посвящена раскрытию темы Суда Божия на примере отрывка (Рим. 1, 18-32). Тема Суда Божия важна для изучения библейского богословия и христианского нравственного учения. Она является общей для посланий апостола Павла, но особенно раскрывается в послании к Римлянам и приобретает новый оттенок в контексте всего Священного Писания и иудейского богословия. Отрывок Рим. 1, 18-32 является первым представлением темы Суда Божия в этом послании св. апостола Павла. В нем можно проследить мотив, функцию, объект и основания Суда Господня над человеком.
The article is devoted to the disclosure of the topic of the Judgment of God on the example of the passage (Rom. 1, 18-32). The topic of the Judgment of God is important for the study of biblical theology and Christian moral teaching. It is common to the epistles of the Apostle Paul, but it is especially revealed in the epistle to the Romans and takes on a new shade in the context of all Holy Scripture and Jewish theology. The passage Rom. 1, 18-32 represents the first presentation of the theme of the Judgment of God in this epistle of St. Paul the Apostle. It is possible to trace the motive, function, object and grounds of the Judgment of the Lord over man in this passage.
Review of the Life Path and Pedagogical Activity of A. I. Anastasiev
Authors: Черкасов Иона 
Published: December 2022

В статье исследуется жизненный путь и педагогическая деятельность Андрея Ивановича Анастасиева. Особое внимание учителей он обращал на внутреннее усвоение учащимися православного учения не только умом, но и сердцем, с пониманием смысла. Поэтому он был сторонником обучения нерусского населения на их родном языке. Для развития в детях искреннего религиозного чувства и усвоения христианских правил в жизни он советовал учителям определенный способ преподавания - урок, который представлял бы собой живую, задушевную и доступную беседу доброго пастыря со своими детьми. Все это было совершенно необходимо в деле миссионерской деятельности Симбирской епархии, оказывающей поддержку миссионерам и приходским священникам в деле обращения иноверцев от заблуждений в истинах веры, утверждения в православии новокрещенных и борьбе с раскольническим движением в губернии. Показательный пример обращения язычника в православную веру, когда его внутреннее умственное и внешнее изменение показывают результаты применения религиозно-воспитательных идей А. И. Анастасиева. Изучение его авторских трудов в настоящее время могло бы мотивировать современного учителя по-новому осознать, что является приоритетом и основой в обучении учащихся, выстраивая весь комплекс учебной и воспитательной работы на основе Евангельских заповедей. Полагаю, что использование исторических сведений, изложенных в данной работе, возможно также при обобщающих исследованиях в учебных пособиях и курсах лекций по истории Симбирской епархии.
The article examines the life path and pedagogical activity of Andrei Ivanovich Anastasiev. He paid attention in his works to the learning of Orthodox teaching through the heart, not just the mind. Therefore, he supported teaching the non-Russian population in their native language. He advised teachers a way of teaching sincere religious feelings in children and the assimilation of Christian rules in life. He taught teachers a specific method of teaching - a method that would represent a lively, sincere and accessible conversation of the pastor with his children. That was necessary for the missionary activity of the Simbirsk diocese, providing support to missionaries and parish priests in the conversion of gentiles from errors in the truths of faith, the establishment of the newly baptized in Orthodoxy, and the fight against the dissident movement in the province. An illustrative example of the conversion of a pagan to the Orthodox faith, when his internal mental and external change shows the results of the religious and educational ideas of A. I. Anastasiev. And studying his author's works at present could motivate a modern teacher to take a fresh look at the priority and basis in teaching students, building the entire complex of educational and educational work based on the Gospel commandments. I believe that the use of historical information presented in this work is also possible with generalizing studies in textbooks and lecture courses on the history of the Simbirsk diocese.
Study of the slant fracture in solid and hollow cylinders: Experimental analysis and numerical prediction
Authors: Ben Chabane Nassima , Aguechari Nassim , Ould Ouali Mohand 
Published: December 2022

This paper is devoted to the numerical and experimental study of ductile fracture in bulk metal forming of the 2017A-T4 aluminum alloy. From an experimental standpoint, the ductile fracture of the 2017A-T4 aluminum alloy is investigated under compressive load. Two cross-sections of solid and hollow specimens are considered. The mechanical behavior and the microstructure of the 2017A-T4 aluminum alloy were characterized. It is found that the well-known barrel shape is obtained when a compressive load is applied. Analyses of fracture topographies show a ductile fracture with dimples under tension and coexistence of ductile fracture with dimples and slant under compression. The classical physically-based Gurson-Tvergaard-Needleman (GTN) model and its extension to incorporate shear mechanisms to predict failure at low-stress triaxiality are considered. These two models have been extended to take into account the thermal heating effect induced by the mechanical dissipation within the material during the metal forming process. The two models have been implemented into the finite element code Abaqus/Explicit using a Vectorized User MATerial (VUMAT) subroutine. Numerical simulations of the forging process made for hollow and solid cylindrical specimens show good agreement with experimental results. In contrast with the GTN model, the modified GTN model incorporating shear mechanisms can capture the final material failure.