bluuebunny/crossref_metadata_2025_split huggingface dataset:
An alternative assessment pathway: Lessons from Australia and New Zealand
Authors: Lakra V. 
Published: August 2023

IntroductionThe COVID-19 pandemic disrupted specialist training across Australia and New Zealand particularly in the area of assessments. Large-scale face-to-face exams were especially vulnerable to disruptions including lockdowns, travel and density restriction and required the Royal Australian and New Zealand College of Psychiatrists (RANZCP) to introduce alternatives.Following several small-scale Objective Structured Clinical Exams (OSCEs) in late 2020 and 2021 (both AV and multi-site), the RANZCP introduced an Alternative Assessment Pathway (AAP) after an exam cancellation in November 2021.ObjectivesTo discuss the introduction of an Alternative Assessment Pathway at the RANZCP and share progress regarding the broader changes to assessment models under consideration.MethodsThe AAP was co-designed with trainees and Specialist International Medical Graduates and introduced in December 2021 as an interim measure to assess clinical competence in the absence of an OSCE. It comprises a portfolio review of completed end-of-rotation forms and, if required, a case-based discussion held via Zoom.ResultsThe AAP has been held over two rounds (December 2021 and March 2022) with 97% and 90% pass rates respectively (data correct as at 6 October 2022). An evaluation into the pathway is currently underway.In July 2022, the RANZCP introduced the Clinical Competency Assessment as a continuation of the AAP (with some modifications) for the remainder of 2022 and 2023.ConclusionsWhile the pandemic has become a catalyst for change, the RANZCP has been considering broader changes to the theory and practice of its assessments for some time. The presentation will provide an overview of its short-term clinical assessment model and share progress regarding change to the long-term assessment strategy.Disclosure of InterestNone Declared
Psychopathological aspects in patients with diabetes
Authors: Trifu S. , Vasile A. I. , Ciubară A. 
Published: August 2023

IntroductionThis paper highlights the mutual influences and the relationships between the variables of type II diabetes, the type of psychiatric conditions, the administered treatment schemes, the imaging examinations and the impact on the functioning and quality of life of the patients.ObjectivesAnalysis of the influences between diabetes and psychiatric disorders, studying the relationships between the variables of type 2 diabetes, the type of psychiatric disorders, treatmentregimens, imaging examinations and the impact on the functioning and quality of life of patients.MethodsPsychiatric interview, Hamilton, Reisberg and Rosenberg scales, laboratory analysysResultsPatients with pre-existing diabetes, psychiatric disorders led to deterioration of its evolution, documented by HbA1c values, treatment schedule, frequency of diabetic emergencies; the increased frequency of psychotic phenomena (hallucinations and delusional ideas) is directly proportional to the number of diabetic emergencies; patients with uncontrolled, long-term diabetes have higher scores on HAM-D and Reisberg scales, while patients with controlled diabetes have higher scores on the self-esteem and quality of life scales; in patients with taste or odor disorders, cortical atrophy may be seen on CT examination, elevated HbA1c levels and the presence of polyneuropathy; alcohol consumption, smoking, high cholesterol levels, determine the advancement of diabetic complications, and these in turn correlate with higher scores on the HAM-D scales, Reisberg; patients who show large variations in blood glucose in the first days after hospitalization are those who exhibit irritability, irritability, nervousness and heteroaggression at the time of hospitalization;Conclusions65% patients with depressive disorders, 10% - with organic personality disorder, 25% - with affective disorders and 30% associated with cognitive impairment. The duration of diabetes mellitus, glycosylated hemoglobin levels and the presence of diabetic complications is directly related to the HAM-D and Reisberg scores; and inversely proportional to quality of life scores and self-esteem.Disclosure of InterestNone Declared
Self-Compassion and General Well-Being among Self-Quarantined Residents: Mediation by Certainty in Control and Moderation by Positive Coping
Authors: Li A. , Wang S. 
Published: August 2023

IntroductionThe outbreak of the Coronavirus Disease 2019 (COVID-19) has caused adverse outcomes on tens of millions of people worldwide, both physically and psychologically. As a public health response, quarantine has been recruited as a national measure in COVID-19, which subjects people who are suspected and confirmed cases to strictly isolation. Unfortunately, people may suffer from various adverse effects under self-quarantine at home. Thus, it is crucial to explore how to improve the psychological outcomes of self-quarantined residents to provide future intervention targets.ObjectivesDuring the COVID-19 pandemic, mandatory quarantine may threaten people’s psychological health and well-being. This study aimed to test the relationship between self-compassion and general well-being among self-quarantined residents and to examine the mediating role of certainty in control (i.e., a component of psychological security) in the relation. It further explored the moderated role of positive coping in the correlation between self-compassion and certainty in control.MethodsParticipants were 312 self-quarantined residents (120 men, 192 women) from a community in Liaoning Province, China, who completed online questionnaires of the Self-Compassion Scale (SCS), Security Questionnaire (SQ), Simplified Coping Style Questionnaire (SCSQ), and General Well-Being Scale (GWBS). A moderated mediation model was conducted to test the hypotheses.ResultsThe moderated mediation model suggested that self-compassion was positively associated with well-being. Certainty in control partially mediated the relationship between self-compassion and general well-being. Moreover, positive coping moderated the relationship between self-compassion and certainty in control. The link between self-compassion and certainty in control was stronger among low-level positive coping people than high-level
ones.ConclusionsFindings reveal that increased psychological security (e.g., certainty in control) by self-compassion contributes to general well-being during the self-quarantined period. People with low positive coping may benefit more from self-compassion. This study thus broadens the understanding of the mechanism underlying self-compassion on positive functioning and well-being. Psychological interventions should focus on self-compassion to enhance the general well-being of quarantined people in the pandemic.Disclosure of InterestNone Declared
Anxiety and depressive disorders in patients with Covid-19
Authors: Stolyarova A. , Tyvina N. , Golovkina D. , Vysokova V. , Zhao J. , Zhang K. , Kinkulkina M. 
Published: August 2023

IntroductionCoronavirus infection has shown a significant impact not only on physical health but also on mental health. Among the long-term consequences in the post-COVID period, depressive and anxiety disorders are well observed. A potential mechanism for developing mental disorders after undergoing SARS-CoV-2 is a neuroinflammatory process in the central nervous system.ObjectivesThis study aimed to discover the features of anxiety and depressive disorders in people who suffered from COVID-19.MethodsThe study was conducted from October 2021 to September 2022 in outpatient and inpatient conditions of the S. S. Korsakov Psychiatric Clinic of Sechenov University. 58 patients (17 (29.3%) men and 41 (70.7%) women) with a diagnosis of F32, F34.1, F41-F48.0, or F06.3-06.4 according to ICD-10 who underwent COVID-19, mainly of mild and moderate severity (46 (79,3%) and (8 (13,8%) consequently), were examined clinically.ResultsThe median age among the respondents was 34 years. Mental illness in the family history had 38 (65.5%) people. Among the examined patients, 21 ((36.2%) people had psychasthenic traits premorbid, 13 (22.4%) – hyperthymic, 9 (15.5%) – hysterical. 15 patients (25.9%) had a history of maternal disorders during pregnancy and childbirth – 16 (27,6%) had neurotic disorders in childhood, 27 (46.6%) had a traumatic brain injury or general anesthesia. 2 patients (3.4%) reported substance abuse, 7 (12.1%) abused alcohol. The median period from somatic well-being after infection to the onset of mental illness was 3 months. The duration from the onset of symptoms of a mental disorder to treatment with a psychiatrist was 3 months. The main symptoms in the clinical picture were impaired concentration (100.0%), decreased productivity (98.3%), sleep disorders (96.6%), decreased mood (98.3%), anxiety (89.7%), anhedonia (75.9%), decreased appetite (65.5%), asthenia (65.5%), emotional lability (44.8%), self-blame ideas (43.1%), obsessive thoughts (39.7%), irritability (37.9%), suicidal thoughts (19.0%).ConclusionsAbout two-thirds of respondents were female. The main reasons for consulting a psychiatrist were decreased concentration, sleep disorders, and reduced productivity. In addition, symptoms of anxiety, asthenia, and low mood were revealed, and more than half of the patients complained of apathy. Although the severity of depression was moderate, and the level of anxiety was mild, all these disorders were accompanied by clinically significant fatigue.Disclosure of InterestNone Declared
Outcomes of a community-based wellness screening tool administered by mental health professionals and religious leaders in the Ketu South Municipality in Ghana
Authors: Wolthusen R. P. F. , Andrä P. 
Published: August 2023

IntroductionGhanaian community members with mental health conditions are usually not identified until their families cannot handle their care at home anymore, for example, due to mistrust in medical institutions. From community-based and global mental health research, we know why we should act (for example, early interventions improve the treatment outcomes) and what we should do (for example, task-sharing in community settings). How any of these activities can be implemented on the community level to decrease the delay of access to evidence-based care remains unclear.ObjectivesThe study explored the “how” for a specific identified problem (collaboration between mental health professionals and religious leaders) in the Ketu South Municipality in Ghana; additionally, the study explored the feasibilty and the results of a community-based wellness screening.MethodsWe used a human-centered design approach to tackle this challenge in the Ketu South Municipality in Ghana. We invited 80 mental health professionals, religious leaders, and service users to participate in this exercise. The participants innovated the so-called Brain Spirit Desk, which builds collaboration between mental health professionals and religious leaders. The participants also designed a 9-question wellness screening tool, including four validated screening scales in Ghana: PHQ-2, GAD-2, one question about suicidality, and CAGE-AID. The participating religious leaders were trained to use this screening tool and administer it by themselves or allow mental health professionals to administer it in their respective institutions. Referral pathways were established for community members who screened positive on the wellness screening tool.Results1065 community members (787 females, 278 males, mean age: 32.42 years) were screened using the wellness screening tool over five months (January - May 2022); 215 of these community members were already connected to mental health clinics in hospitals. 60 community members out of 203 who screened positive on the PHQ-2 were not receiving treatment at the time of screening and were referred for further assessment and treatment. Another 52, 53, and 142 community members were referred for further evaluation and treatment based on their answers to the GAD-2, suicidality, and CAGE-AID screening questions, respectively. Completed referrals across conditions averaged around 55%.ConclusionsOur activities explored, guided through principles of a human-centered design approach, how the delay in access to evidence-based mental health care in the Ketu South Municipality in Ghana can be decreased through a collaborative effort of mental health professionals and religious leaders. A developed screening tool identified potential cases of mental health conditions. Importantly, religious leaders’ involvement and endorsement built trust in the activities.Disclosure of InterestNone Declared
Attitude Toward Depression in Thai Physicians compared with general population
Authors: Charnsil C. 
Published: August 2023

Introduction
High stigma has been considered an important cause for the low rates of help-seeking,
lack of access to care, undertreatment, material poverty, and social
marginalization.Physicians commonly know about depression but are reluctant to seek mental
health treatment.

Objectives
This study aimed to examine the attitude toward depression in Thai physicians compared
with the general population.

Methods
A cross-sectional descriptive study was conducted on Thai physicians and the general
population. We used the Depression Stigma Scale in the Thai version to assess stigma. The
Depression stigma scale was distributed via the internet with a google form program.

Results
Two thousand eighty-three participants responded to the questionnaire. Comparing the
Depression Stigma Scale of the general population and physicians by using an independent test
demonstrated that there was a significant difference between the two groups (p < 0.001)
with an average total score of physicians higher than the general population (37.47 and
35.73, respectively). There was a significant difference in the Perceived Stigma Subscale in
the general population p < 0.001 and physicians but not in the Personal Stigma Subscale. A
significant difference was shown between the Personal Stigma Subscale of male and female
physicians (P < 0.05). No significant difference was demonstrated between the Perceived
Stigma Subscale of male and female physicians. However, the male and female general
population had no significant differences in the Depression Stigma Scale.

Conclusions
Physicians had higher depression stigma than the general population, especially in
perceived stigma.

Disclosure of Interest
None Declared
How co-production helped to shape Well Parent Japan: A culturally appropriate parenting intervention for mothers of children with ADHD
Authors: Shimabukuro S. 
Published: August 2023

AbstractThis presentation will talk about co-production findings from three completed studies to develop and evaluate a culturally appropriate Japanese version of the New Forest Parent Training Programme (NFPP), named Well Parent Japan (WPJ). Dr Shimabukuro will also present an on-going prospective study aiming to provide support for Japanese mothers and teachers of children with ADHD in a school setting. Dr. Shimabukuro will share the experiences worked with different stakeholders at the different stage of the study and highlight the benefits of co-production in the research and how WPJ was shaped. This presentation will also discuss difficulties and challenges when evidence-based parent training intervention is transferred from research to practice.Disclosure of InterestNone Declared
Emotionally Unstable Personality Disorder and Severity of Suicide Attempt are related to Epigenetic Hypermethylation of Brain-Derived Neurotrophic Factor in Women
Authors: Jokinen J. , Jamshidi E. , Nilsonne Å. , Wilczek A. , Boström A. , Åsberg M. 
Published: August 2023

IntroductionBrain-derived neurotrophic factor (BDNF) has been associated with both emotionally unstable personality disorder (EUPD) and suicidal behavior. No study has yet investigated BDNF-associated epigenetic alterations in severely impaired EUPD and suicidal patients.ObjectivesThe main goal of the present study was to investigate whether epigenetic dysregulation in BDNF, CRP, IL-1, IL-2 and IL-6 were associated with EUPD and severity of suicidal behavior.MethodsThe discovery cohort consisted of 97 women with emotionally unstable personality disorder (EUPD) with at least two serious suicide attempts (SA) and 32 healthy women. The genome-wide methylation pattern was measured by the Illumina EPIC BeadChip and analyzed by robust linear regression models to investigate mean BDNF methylation levels in a targeted analysis conditioned upon severity of suicide attempt. The validation cohort consisted of 60 female suicide attempters, stratified into low- (n=45)and high-risk groups (n=15) based on degree of intent-to-die and lethality of suicide attempt method, and occurrence of death-by-suicide at follow-up.ResultsMean BDNF methylation levels exhibited hypermethylation in relation to EUPD(p=0.0343, percentage mean group difference ~3.8%). Similarly, this locus was confirmed as hypermethylated in an independent cohort of women with severe suicidal behavior (p=0.0469). Results were independent of age and BMI.ConclusionsThis study elicits emerging evidence of epigenetic dysregulation of BDNF in relation to phenotypes known to increase risk of suicide (lethality of suicide-attempt method and presence of EUPD diagnosis with history of recent SA). Further studies investigating epigenetic and genetic effects of BDNF on severe suicidal behavior and EUPD are needed to elucidate the role of epigenetic regulatory mechanisms and neurotrophic factors in relation to suicide risk.Disclosure of InterestNone Declared
Mental Health Services Utilization among Suicidal Patients: Comparing the Impact of Co-Occurring Opioid or Other Substance Use Disorders
Authors: Pathak J. 
Published: August 2023

IntroductionPrior literature establishes bidirectional associations between suicide and substance use disorders (SUDs), particularly opioid use disorder (OUD). However, the context of mental health services utilization remains under-investigated. This analysis examined patterns of mental health services utilization in patients with SUDs and suicidality, identified associated risk factors, and evaluated the impact of patient engagement on subsequent mental health outcomesObjectivesSee above.MethodsElectronic health records (EHRs) derived from 7 health systems across New York City between 2010-2019 were analyzed. Suicidality was identified as any ICD-9/10 diagnosis of suicide attempt, suicidal ideation, or self-harm injury. SUDs were identified as any opioid, cannabis, cocaine, hallucinogen, inhalant, sedative/hypnotic/anxiolytic, amphetamine, or other substance abuse or dependence. Quasi-Poisson regression adjusted for age, gender, and chronic diseases was used to model associations between OUD exposure and the frequency of encounters and estimate the relative risk (RR) of significant covariates.ResultsA total of 6977 adults with suicidality and any comorbid SUD were selected, including 2203 (31.6%) with a diagnosis of OUD and 4774 (68.4%) without a diagnosis of OUD. Most patients were male (54.8%) and aged between 25-64 years (79.3%). Many (61.3%) had over 3 chronic diseases, including depression (80.8%), hypertension (60.6%), anemia (43.0%), and hyperlipidemia (41.9%). Compared to patients with other SUDs, those with OUD had higher odds of self-harm injury [OR: 1.26 (95% CI: 1.13-1.41)], depressive disorders [1.47 (1.29-1.67)], anxiety disorders [1.65 (1.48-1.84)], psychotic disorders [1.23 (1.11-1.37)], personality disorders [1.30 (1.16-1.48)], and post-traumatic stress disorder [1.37 (1.20-1.57)]. Patients with OUD were more likely to utilize all-cause outpatient (RR: 1.16), emergency department (ED) (RR: 1.43), and inpatient (RR: 1.60) services (p<0.001). Among OUD patients, males were less likely to have outpatient visits (RR: 0.79) and inpatient hospitalizations (RR: 0.88), and older age was protective against ED admissions (RR range: 0.62-0.71). Additionally, individuals with OUD were more likely than those with other SUDs to have SUD-related encounters, as well as suicide-related ED admissions and inpatient hospitalizations (p<0.0001). Those who had more mental health outpatient visits were less likely to have suicide-related ED admissions (RR: 0.85), however this association was weaker among younger or male patients with comorbid OUD.ConclusionsAmong suicidal adults with comorbid SUDs, those with a diagnosis of OUD were more likely to utilize mental health services and have psychiatric comorbidity. Males and older adults were less likely to utilize services.Disclosure of InterestNone Declared
Borderline personality disorder and attention deficit/hyperactivity disorder in adolescence: overlap and differences in a clinical setting
Authors: Akca O. F. , Wall K. , Sharp C. 
Published: August 2023

IntroductionWith increased consensus regarding the validity and reliability of diagnosing Borderline PersonalityDisorder (BPD) in adolescents, clinicians express concern over the distinction between BPD and Attention-Deficit/Hyperactivity Disorder (ADHD), and its co-morbidity in clinical settings.ObjectivesThe goal of this study was to evaluate differences between BPD, ADHD and BPD + ADHD in terms of co-morbid psychiatric disorders and a range of selfreported behavioral problems in adolescents.MethodsOur sample consisted of N = 550 inpatient adolescents with behavioral and emotional disorders that have not responded to prior intervention. We took a person-centered approach (for increase clinical relevance) and compared adolescents with ADHD, BPD and ADHD+BPD in terms of co-occurring psychiatric disorders and behavioral problems. We performed a regression analysis to test whether BPD symptoms make an incremental contribution to the prediction of psychiatric symptoms over ADHD symptoms.ResultsThe severity of almost all co-occurring disorders, aggression, self-harm, suicidal thoughts, and substance use, were higher in the ADHD+BPD group. Borderline symptoms made an incremental contribution to the prediction of psychiatric symptoms beyond the contribution of ADHD.ConclusionsThe findings of this study demonstrated that ADHD and BPD have different psychiatric symptomatology. In addition, subjects who meet criteria for both the BPD and ADHD diagnoses may have more severe psychiatric and behavioral problems compared to individuals with only ADHD or BPD.Disclosure of InterestNone Declared