bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comprehensive voxel-wise, tract-based and network lesion mapping reveals unique architectures of right and left visuospatial neglect
Authors: Moore Margaret Jane , Hearne Luke , Demeyere Nele , Mattingley Jason B. 
Published: May 2023

Abstract

Visuospatial neglect is a common, post-stroke disorder of perception which is widely considered to be a disconnection syndrome. However, the patterns of dysconnectivity associated with neglect remain unclear. Here we had 530 acute stroke survivors (age = 72.8 (SD = 13.3), 44.3% female, 7.5 days poststroke (SD = 11.3)) undertake routine clinical imaging and standardised neglect testing. The data were used to conduct voxel-wise, tract-level, and network-level lesion-mapping analyses aimed at localising the neural correlates of left and right egocentric (body-centred) and allocentric (object-centred) neglect. Only minimal anatomical homogeneity was present between the correlates of right and left egocentric neglect across all analysis types. This finding challenges previous work suggesting that right and left neglect are anatomically homologous, and instead suggests that egocentric neglect may involve damage to a shared, but hemispherically asymmetric attention network. By contrast, egocentric and allocentric neglect were associated with dysconnectivity in a distinct but overlapping set of network edges, with both deficits related to damage across the dorsal and ventral attention networks. Critically, this finding suggests that the distinction between egocentric and allocentric neglect is unlikely to reflect a simple dichotomy between dorsal versus ventral networks dysfunction, as is commonly asserted. Taken together, the current findings provide a fresh perspective on the neural circuitry involved in regulating visuospatial attention, and provide important clues to understanding the cognitive and perceptual processes involved in this common and debilitating neuropsychological syndrome.
The Origin and Stability of Pit Lake Water in Baiyinhua, Inner Mongolia, based on Hydrochemistry and Stable Isotopes (δD, δ18O)
Authors: Pei Shengliang , Zhang Deqiang , Wang Shining , Zhang Zhaodi 
Published: May 2023

Abstract

The Baiyinhua area of Inner Mongolia is rich in coal resources but lacks water resources. Water required for ecological restoration in mining area is primarily obtained via pit lake water recycling. However, robust data has not yet been obtained to characterize the nature of the source, evaporation, and supply of the pit lake water. In this study, 20 groups of different water samples in the Baiyinhua mining area were collected, which were subjected to chemical analysis to determine the contents of hydrogen and oxygen stable isotopes (δD, δ18O) and ion ratios. By principal component analysis and the Rayleigh fractionation model, the mechanisms of pit lake water formation and the extent of its evaporation in the Baiyinhua mining area were revealed. The results show that the hydrochemical type of the pit lake water in the Baiyinhua mining area of Inner Mongolia is the HCO3-SO4-Na type,which is different from the surrounding water bodies (HCO3-Na-Ca and Cl-HCO3-Na types). The formation of pit lake water is mainly affected by evaporation (69.42%) and is less affected by groundwater recharge (17.06%) and human activities (11.51%). Due to its open area and relatively closed system, the evaporative loss of the pit lake water is relatively large, at about 40%-61% of the initial water body, which is 1%-22% higher compared to a nearby natural water body.
Endmember Extraction and Abundance Estimation Algorithm Based on Double-Compressed Sampling
Authors: Wang Li , Bi Yang , Wang Wei , Li Junfang 
Published: May 2023

Abstract
Based on double-compressed sampling, a hyperspectral spectral unmixing algorithm is proposed, which could directly complete the endmember extraction and abundance estimation. On the basis of the linear mixed model, we designed spatial and spectral sampling matrices, obtained spatial and spectral measurement data, and constructed a joint unmixing model containing endmember and abundance information. By using operator separation and Lagrangian multiplier algorithm, the endmember matrix, abundance matrix and remixing image can be quickly obtained by matrix operation. The parameters of the unmixing algorithm, including regularization parameter, convergence threshold and spatial sampling rate, are determined using synthetic simulated hyperspectral data. The proposed algorithm is applied to six groups of real hyperspectral data, and the experimental results fully verify the effectiveness and reliability of the algorithm. Compared with the algorithm that directly unmixes the original data, it is found that the proposed algorithm can effectively extract the endmembers and estimate the abundance even when there are few measurement data. Compared with the algorithm of sampling reconstruction first and then unmixing, the proposed algorithm can improve the efficiency of unmixing. Therefore, the main innovation of the proposed algorithm is that it can complete the unmixing directly from the measured data, maintain the accuracy and improve the efficiency of the unmixing.
Evaluation of COVID-19 m-Health Apps: An Analysis of the Methods of App Usability Testing During a Global Pandemic
Authors: Saeidnia Hamid Reza , Kozak Marcin , Ausloos Marcel , Lund Brady D. , Ghorbi Ali , Mohammadzadeh Zahra 
Published: May 2023

Abstract
Purpose: As the COVID-19 outbreak expanded over the world, governments looked for smartphone-based technological solutions to reduce the disease's dangers and prevent it. Most leading governments initially sought to use new smartphone-based applications (apps). In this study, we review articles that have evaluated these official government apps. The objective of this review is to answer the following question: “In evaluating or analyzing governmental apps for COVID-19, which methods have researchers used?”.
Methods: This study reviews existing scholarly literature, to identify and analyze the investigations into the usability evaluation of official (governmental) mobile apps developed in the COVID-19 era. Study parameters specified that articles must be originally published in peer-reviewed journals or short articles, written in English, and must be published between 2019 and 2022 and indexed in PubMed, OVID, EMBASE, Web of Science, and Scopus. Additionally, the articles had to analyze and evaluate at least one mobile app that was launched and/or supported by a government. Reports, letters to the editor, review articles, and meta-analyses were excluded; also excluded were articles processing non-governmental apps.
Results: 11 studies were identified that met the inclusion criteria. These studies evaluate a total of 40 governmental, “official”, mobile apps, developed in 41 countries from the five continents. This study finds that the heuristic method, thematic analysis, and comparative analysis are the most popular research methods used for evaluating or analyzing governmental apps for COVID-19.
Conclusion: This review of articles developed by various governments to combat COVID-19 leads the authors to conclude that most researchers sought to emphasize the strengths of these apps as opposed to limitations. Based on this review, we find that existing literature can sufficiently cover the effectiveness of these mobile applications.
Closing the Loop: Autonomous High-Throughput Strain Characterisation from Frozen Cell Bank to Product Assay
Authors: Helleckes Laura Marie , Puchta Debora , Czech Hannah , Morschett Holger , Geinitz Bertram , Wiechert Wolfgang , Oldiges Marco 
Published: May 2023

Abstract
Background: Modern genome editing enables rapid construction of genetic variants, which are further developed in Design-Build-Test-Learn cycles. To operate such cycles in high throughput, fully automated screening, including cultivation and analytics, is crucial. Here, we present the required steps to meet these demands, resulting in an automated microbioreactor platform that is able to close the experiment-model loop for phenotyping.
Results: First, an automated deep freezer was integrated into the robotic platform to provide working cell banks at all times. A mobile cart allows flexible docking of the freezer to multiple platforms. Next, precultures were integrated within the microtiter plate for cultivation, resulting in highly reproducible maincultures as demonstrated for Corynebacterium glutamicum. To avoid manual exchange of microtiter plates after cultivation, two clean-in-place strategies were established and validated, resulting in restored sterile conditions within two hours. Combined with the previous steps, these changes enable a flexible start of experiments and greatly increase the walk-away time.
Conclusions: Overall, this works demonstrates the capability of our microbioreactor platform to perform autonomous, consecutive cultivation and phenotyping experiments. As demonstrated in a case study of cutinase-secreting strains of C. glutamicum, the new procedure allows for flexible experimentation without human interaction while maintaining high reproducibility in early stage screening processes.
Sialorrhea in the assessment and correction of water balance in a 2 month old baby in the ICU: a case report
Authors: Lazarev Vladimir V. , Megeryan M. M. , Smirnov D. A. , Bykov M. V. , Frolov N. S. 
Published: May 2023

INTRODUCTION: In some cases, saliva production (sialorrhea — hypersalivation) can be so significant that it needs to be monitored and accounted for in the assessment and maintenance of the patient's water balance. OBJECTIVE: Description of a clinical case of sialorrhea, which had a clinically significant manifestation in the assessment and maintenance of water balance in a 2-month-old child in the intensive care unit (ICU). MATERIALS AND METHODS: Baby, 2 month old, was treated in the ICU with a diagnosis: perinatal organic hypoxic-ischemic lesion of the central nervous system of a newborn, congenital pathology of the brain, respiratory failure III stage, convulsions of the newborn, neonatal coma. In the complex of specific therapy, he received enteral feeding, correction of water and nutritional status. RESULTS: On the first day of detection of sialorrhea, the level of salivation of 2.81 ml/kg/hour (the norm is 1.3 ml/kg/hour) exceeded the physiological values by more than 2 times. The excess of normal values of salivation persisted for the next two days, as well as on the 9th day of its control, which required taking into account the amount of fluid lost with saliva in the calculation of its daily requirement. No specific measures were required in the treatment of the patient to eliminate sialorrhea; within 14 days from the moment the fact of sialorrhea was established, the level of salivation returned to normal values. CONCLUSIONS: In assessing the cumulative factors that cause fluid loss in ICU patients, especially infants, it is also necessary to take into account the presence and intensity of salivation, which can manifest as sialorrhea, when calculating the volume and administration of infusion drugs.
Bleeding disorders associated with severity of respiratory failure in COVID-19 patients: a prospective observational study
Authors: Neymark Mikhail I. , Momot A. P. , Nikolaeva M. G. , Маmаеv А. N. , Proskurin S. N. , Logvinov P. V. , Karkavina A. N. , Epp D. P. , Romanov V. V. 
Published: May 2023

INTRODUCTION: Despite the progress in understanding the pathophysiology of coagulopathy in COVID-19, data about the association and phasing of pathological changes in various parts of the hemostatic system with the development of acute respiratory distress syndrome (ARDS) are insufficient. OBJECTIVE: To determine association between the severity of respiratory failure and pathological changes in the hemostatic system in COVID-19 patients. MATERIALS AND METHODS: A prospective observational study included 204 patients with a confirmed diagnosis of severe and extremely severe COVID-19. Two groups were identified according to disease outcome: fatal (n = 106) and survived (n = 98) groups. To assess dynamics of the clinical picture of the disease and to study the hemostatic profile, time points were determined: I point — the first day — admission to intensive care unit; II point — 3–5 days, III point — 7–10 days after ICU admission. The respiratory index was calculated to assess the severity of respiratory distress syndrome. Statistical data processing was carried out using the statistical software package MedCalc Version 20.110 (MedCalc Software Ltd, Belgium). RESULTS: A 2.15-fold decrease in the respiratory index was determined for fatal outcome in patients with severe and extremely severe COVID-19. The most important hemostatic parameters affecting the severity of respiratory failure are increased Willebrand factor concentration at I point of the study (21 % contribution and inverse correlation), increased plasminogen activator inhibitor type 1 (PAI-1) level on 3–5 days (35 % contribution and direct correlation), and activation of the coagulative component of hemostasis on 7–10 days (78 % contribution and direct correlation). CONCLUSIONS: The severity of respiratory failure in patients with a confirmed diagnosis of severe and extremely severe COVID-19 is gradually associated with endotheliopathy (1 day), inhibition of parietal fibrinolysis (3–5 days) and activation of the coagulative component of hemostasis by 7–10 days of ICU stay.
Hubungan layanan perpustakaan sekolah dengan minat baca peserta didik di SMAN 4 Kota Tangerang Selatan
Authors: Rahman Aditiya , Lolytasari Lolytasari , Munawwaroh Zahrotul 
Published: April 2023

Introduction. Providing school library services to increase students' interest in reading is still an important study for school libraries. Increasing reading interest in the SMAN 4 Tangerang Selatan Library is carried out by providing collaborative services to improve scientific communication. This research needs to be carried out so that the services provided by the library can accommodate all students in reading interest services and become basic research for school libraries in the South Tangerang area.Methodology. This study uses a quantitative approach, with a correlation coefficient test to answer the hypothesis. The population is 346 students, so a sample of 186 respondents is obtained using a simple random sampling technique. Questionnaires were distributed to 186 students with Likert scale scores with four alternative answers and documentation studies to complete data collection.Results and Discussion. This study found a relationship between library services and students' reading interest, as evidenced by the contribution of 24.6% between library services and students' reading interest. In comparison, the remaining 75.4% was explained by other variables not examined. The tendency of library services to increase reading interest is still in the moderate category.Conclusion. This study describes the school's efforts to increase student's interest in reading with the strength of the services provided by the library. Reading skills need to be trained so that the more the library can provide the facilities needed for reading, the more trained students will be.
Content preservation analysis of Semarang City tourism website
Authors: Pramudibyanto Hascaryo 
Published: April 2023

Background. Semarang City tourism site is a means to market the tourism business industry has not been managed properly. The niche on the tourism website has not shown a complete description of the actual conditions of a digital collection preservation effort. This study aims to analyze content preservation on tourism websites in Semarang City. The purpose of this research is to describe the excellence of Semarang City tourism website when filled with complete and attractive content.Methodology. This study on preservation analysis of tourism websites uses descriptive qualitative methods by conducting media content analysis on the tourism website http://pariwisata.semarangkota.go.id/ as tourism information navigation. The core of the problem studied is the lack of relevance of Semarang City's development plan as a smart city with the readiness of tourism information. Results and discussion. The results of the content analysis of the preservation of the site found that the content of the site has not fully conveyed actual and interesting ideas, ideas, or information.Conclusions. Preservation efforts have been done well, but the quality of this niche on the site needs to be improved. This site is still undergoing an application maintenance process so there is a delay in updating the site content. Suggestions for site improvement include providing opportunities for the community to send coverage products about tourism activities through an editing process to harmonize the content with other aspects of beauty. Visitors expect an honest statement from the site manager to apologize that this site is undergoing application maintenance or preservation so that visitors can figure out the actual situations
Hybrid membrane process for water treatment: a short review
Authors: Saha Pratik , Jampa Surendra Sasikumar , Sinha Manish Kumar , Khuntia Snigdha 
Published: May 2023

Abstract
Water shortage is one of the most difficult issues confronting people all over the world. Rapid urbanization and water scarcity necessitate immediate action to improve sustainable water management without jeopardizing global socioeconomic growth. Thus, conventional water treatments are implemented for the purpose of eradicating various pollutants in wastewater. Traditional water treatment methods, whether in water treatment facilities or reverse osmosis (RO) plants, have run across a number of roadblocks that have significantly hampered their performance and efficiency. Integrating the membrane process with other remediation technologies in a hybrid process is a novel technique to improve contaminant extraction efficiency for our target streams. This process is termed the hybrid membrane process (HMP). On this aspect, this paper would highlight the benefits of using the HMP compared to conventional methodologies and their applications conducted in various sectors around the world. Some case studies are also reviewed illustrating its cost analysis in comparison to conventional methodologies accentuating the merits of using HMPs.
Assessment of the Coefficient of Tension in the Labor Market. Regional Aspect
Authors: Koshevoy O. S. 
Published: May 2023

.Assessing the situation in the labor market of the region, and ultimately forecasting the level of employment and unemployment, is a complex multidimensional mathematical problem that does not have a reliable and proven solution to date. Research in the direction of creating evaluation methods and forecasting the situation on the labor market is an actual task. The subject of the work is an assessment of the situation on the labor market of the Volga Federal District, through the analysis and modeling of the coefficient of tension in the labor market. The purpose of the study was to develop a methodology that allows making a preliminary forecast of the situation on the labor market of the subject of the Volga Federal District. The information base of the study was the results of a sample survey of the labor force conducted by state statistics bodies in accordance with the classifier of objects of administrative-territorial division (OKATO – Russian Classification on Objects of Administrative Division). To date, the length of the time series is four time periods (2018–2021) of the year. As methods of analysis and modeling, methods of descriptive statistics were used, as well as mathematical modeling of the relationship between the coefficient of tension in the labor market and the rating index of the socio-economic situation of the Volga Federal District. It is shown that the statistical grouping of the coefficient of tension in the labor market as a whole for all subjects of the Russian Federation is extremely heterogeneous, which makes it difficult to model processes in the labor market. At the same time, the statistical grouping of the coefficient of tension in the labor market of the regions of the Volga Federal District is quite homogeneous, which makes it possible to carry out simulations using such an integral index as the rating of the socio-economic situation of the subject of the Volga Federal District. In the process of modeling in the environment of the SPSS computer program, a nonlinear regression model of the relationship between the coefficient of tension in the labor market (dependent variable) and the place in the rating of the socio-economic situation of the subject of the Volga Federal District (explanatory variable) was formed. The model allows you to make a preliminary forecast of the situation on the labor market of the subject of the Volga Federal District.
Socio-Economic Factors of Population Reproduction in Russia and in the Context of Federal Districts
Authors: Gulyaeva T. I. , Takmakova E. V. , Savkin V. I. 
Published: May 2023

The purpose of the study. Establishing the specifics of reproduction of the Russian population in the modern conditions of economic development in general and in the context of federal districts.Materials and methods. In the process of writing the article, the authors used regulatory legal acts of the Government of the Russian Federation, materials of the Federal State Statistics Service, the works of individual scientists and public organizations on the problems of population reproduction. In the course of the work, such statistical research methods as tabular and graphical methods, analysis of indexes of dynamics series were used.Results. The population of the Russian Federation and the components of its change for 1990-2021, the dynamics of fertility and mortality rates for 1950-2021 were studied, the reasons for the decline in the total fertility rate and the net coefficient of population reproduction, including in the context of federal districts, were considered.Conclusion. Currently, the population of the Russian Federation has not reached the level of 1990. Fluctuations in the total population growth are mainly caused by fluctuations in migration growth. In conditions of low fertility and high mortality, the migration component is the determining factor of population growth. Since 1992, the natural decline of the population has been established (with the exception of 2013-2015). The amount of migration growth exceeded the natural decline in 2009-2017, which ensured the overall population growth.The intersection of the curves of the dynamics of the fertility rate and the mortality rate in the Russian Federation was established in 1992 and 2016. From 2012 to 2016 the coefficient of natural growth is approaching zero, and then a downward trend is formed, that is, a decrease in the population.The main reason for the decline in the birth rate in Russia is the demographic, socio-economic state of society, in which a steady decline in the total fertility rate, demographic aging of the population, and changes in the family structure have been established. Over the past 30 years, there has been a narrowed reproduction of the population in the country, which can be considered as a potential depopulation.A high variation of the total fertility rate in the context of federal districts of Russia has been established. In the Central Federal District and the North-Western Federal Districts for the period 1990-2021, the total fertility rate did not exceed the average Russian level of this index. Over the past three years (2019-2021), the total fertility rate has been decreasing in the Northwestern, Southern, Volga, and Siberian Federal Districts.In order to eliminate negative trends in the birth rate in the regions, it is necessary to create jobs, form normal housing conditions, ensure sustainable growth in real income of the population, organize a modern level of healthcare, education, develop a network of preschool institutions, and support families.