bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reliability and validity of pose estimation algorithm for measurement of knee range of motion after total knee arthroplasty
Authors: Saiki Yoshitomo , Kabata Tamon , Ojima Tomohiro , Kajino Yoshitomo , Kubo Naoyuki , Tsuchiya Hiroyuki 
Published: May 2023

AimsWe aimed to assess the reliability and validity of OpenPose, a posture estimation algorithm, for measurement of knee range of motion after total knee arthroplasty (TKA), in comparison to radiography and goniometry.MethodsIn this prospective observational study, we analyzed 35 primary TKAs (24 patients) for knee osteoarthritis. We measured the knee angles in flexion and extension using OpenPose, radiography, and goniometry. We assessed the test-retest reliability of each method using intraclass correlation coefficient (1,1). We evaluated the ability to estimate other measurement values from the OpenPose value using linear regression analysis. We used intraclass correlation coefficients (2,1) and Bland–Altman analyses to evaluate the agreement and error between radiography and the other measurements.ResultsOpenPose had excellent test-retest reliability (intraclass correlation coefficient (1,1) = 1.000). The R2 of all regression models indicated large correlations (0.747 to 0.927). In the flexion position, the intraclass correlation coefficients (2,1) of OpenPose indicated excellent agreement (0.953) with radiography. In the extension position, the intraclass correlation coefficients (2,1) indicated good agreement of OpenPose and radiography (0.815) and moderate agreement of goniometry with radiography (0.593). OpenPose had no systematic error in the flexion position, and a 2.3° fixed error in the extension position, compared to radiography.ConclusionOpenPose is a reliable and valid tool for measuring flexion and extension positions after TKA. It has better accuracy than goniometry, especially in the extension position. Accurate measurement values can be obtained with low error, high reproducibility, and no contact, independent of the examiner’s skills.Cite this article: Bone Joint Res 2023;12(5):313–320.
The perioperative utility of 3D printed models in complex surgical care: feedback from 106 cases
Authors: Thorn C , Ballard J , Lockhart C , Crone A , Aarvold A 
Published: May 2023

Introduction 3D models are an emerging tool for surgical planning, providing an augmented method for the visualisation of a patient’s anatomy. As their use increases, more data about the utility of these models is critical to inform budget allocation. This study provides the most comprehensive analysis to date for the use of 3D models in perioperative management. Methods 3D models for complex surgical cases in NHS hospitals were delivered alongside a surgeon feedback survey. The survey on the model’s utility had been designed alongside the university data analytical team and focused on five areas: surgical planning and diagnosis, economic impact, impact on intraoperative and preoperative time, effect on communication and direct impact on the patient. Results There were 106 models used by 63 surgeons for complex surgical cases between May 2020 and March 2021, across multiple surgical specialties. The models were reported to have benefits in all perioperative areas, with 92.5% of responses agreeing that the 3D model was a better method for diagnosis and planning than traditional 2D techniques. Benefits were reported on preoperative planning (92.4%), economic savings due to equipment selection (54.4%), reduction in surgical time (41.5%) and surgeon-to-surgeon communication (92.6%). Conclusion 3D models were shown to have a wide range of benefits in a surgical setting. The reduction in surgical time could have the potential to help alleviate surgical backlogs. With more widespread use and optimisation of costs the use of 3D models could become the standard for unusual and complex surgical cases.
Chest wall reconstruction reduces hospital mortality following major chest wall trauma: a retrospective cohort study
Authors: Cheruvu MS , Chubsey R , Blagojevic-Bucknall M , Satur CMR 
Published: May 2023

Introduction Chest wall reconstruction was introduced for the management of patients with severe chest wall injuries. We undertook a retrospective cohort study to investigate whether the treatment was associated with improved survival compared with conservative treatment. Methods A retrospective single institutional cohort study compared mortality following treatment of major chest wall trauma (Abbreviated Injury Scale ≥3) by chest wall reconstruction (CWR) to conservative management (Non-CWR) between September 2014 and December 2019. Univariable and multivariable associations between demographic and comorbid characteristics and mortality were estimated using Cox proportional hazard analysis and expressed as hazard ratios (HR) and corresponding confidence intervals (CI). Results Of a cohort of 947, CWR (n=157, 16.6%) had a lower prevalence of polytrauma (35.7 vs 56.3%, p<0.001) and head injury (11.5% vs 26.7%, p<0.001). CWR-treated patients experienced a greater number of fractured ribs, (8.3 vs 5.8, p<0.001), higher incidence of flail chest (84.9% vs 48.9%, p<0.001), higher admission to Critical Care (64.3% vs 44.1%, p<0.001), greater demand for ventilation (36.9% vs 25.6%, p=0.004) and a higher New Injury Severity Scale value (36.9 vs 34.6, p=0.003). Mortality of CWR patients was significantly lower (3.8% vs 8.6%, p=0.04), with adjusted HR 0.30 (95% CI 0.12, 0.72, p=0.008). Conclusions Chest wall reconstructive surgery, provided as a part of multidisciplinary treatment strategy for major thoracic trauma, reduces risk of mortality. The results validate the UK Government strategy, designed to reduce mortality, by centralising management of serious trauma in Major Trauma Centres.
Anatomical injury patterns, demographics and outcomes data for blunt and penetrating neck injuries on the Trauma Audit and Research Network database
Authors: Dodds N , Hollis S , Islam M , Thompson J 
Published: May 2023

Introduction Penetrating neck trauma is a relatively rare though potentially devastating mode of injury. To date, there has been no analysis on this subject using the Trauma Audit and Research Network (TARN) dataset for the population of England, Wales and Northern Island. Methods This was a retrospective observational study using the TARN dataset to identify all adult patients (≥16 years) presenting with neck trauma between January 2012 and March 2019. Results A total of 2,395 patients met the inclusion criteria for this study: 1,584 with blunt injuries to the neck (374 isolated injuries) and 811 with penetrating neck injuries (412 isolated injuries). The median age of the study population was 44.2 years and 73% were male. The unadjusted mortality rate was 18.2%. Seventy-nine per cent of patients with penetrating injuries required surgical exploration. The odds ratios (ORs) of injury to the trachea, pharynx/retropharynx, jugular vein and larynx were all significantly increased with penetrating injuries to the neck. There was significantly increased mortality for those patients suffering hyoid bone injury (OR: 3.07, 95% confidence interval [CI]: 2.10–4.49), carotid artery injury (OR: 1.81, 95% CI: 1.41–2.32) and laryngeal injury (OR: 1.25, 95% CI: 0.95–1.65). Conclusions Our data highlight the potentially devastating consequence of neck injury with associated injury patterns. Patients suffering penetrating neck trauma have complex care requirements needing appropriate specialty input.
Highly sensitive and reliable optical fiber TDLAS gas detection system for methane in situ monitoring in near space
Authors: Zhang Qinduan , Zhang Tingting , Wei Yubin , Liu Tongyu 
Published: May 2023

A highly sensitive and reliable tunable diode laser absorption spectroscopy gas detection system with a temperature–pressure compensation algorithm is demonstrated for detecting CH4 concentrations in near space. Near space generally refers to the airspace 20–100 km away from the ground, where temperature and pressure changes are complex. Since the gas absorption spectrum is easily affected by temperature and pressure, a temperature–pressure compensation algorithm is proposed and used in the CH4 sensor to improve the detection accuracy of the sensor. First, we measured the basic characteristics of the sensor in the laboratory, such as linearity and long-term stability. Experimental results showed that the linear correlation coefficient R-square can reach 0.999, and the concentration fluctuation of CH4 is less than 0.17 ppm within 3.5 h. Then the sensor was applied to a research activity in Qinghai Province, China, in September, and the results show that the sensor can effectively monitor the CH4 concentration in near space.
COVID-19 in patients with paracoccidioidomycosis
Authors: de Macedo Priscila Marques , Benko Lorena Macedo Pestana , Falcão Eduardo Mastrangelo Marinho , Nosanchuk Joshua D. , Almeida-Paes Rodrigo , do Valle Antonio Carlos Francesconi 
Published: May 2023

Introduction
In 2020, we reported the first patient with concomitant COVID-19 and paracoccidioidomycosis (PCM). Since then, no other cases have been recorded in the literature. We aim to update information on the occurrence of COVID-19 in patients with PCM followed at a reference center for infectious diseases at Rio de Janeiro, Brazil.

Methods
We reviewed the medical records from patients diagnosed with PCM who presented with clinical symptoms, radiological findings, and/or laboratory diagnosis of COVID-19 at any time during their acute or follow-up care. The clinical profiles of these patients were described.

Results
Between March 2020 and September 2022, we identified six individuals with COVID-19 among the 117 patients with PCM evaluated. The median age was 38 years and the male to female ratio 2:1. Most patients (n = 5) presented for evaluation due to acute PCM. The severity of COVID-19 ranged from mild to severe in acute PCM and only the single patient with chronic PCM died.

Conclusions
There is a range of disease severity in COVID-19 and PCM co-infection and concomitant disease may represent a severe association, especially in the chronic type of the mycosis with pulmonary involvement. As COVID-19 and chronic PCM share similar clinical aspects and PCM is neglected, it is probable that COVID-19 has been hampering simultaneous PCM diagnosis, which can explain the absence of new co-infection reports. With the continued persistence of COVID-19 globally, these findings further suggest that more attention by providers is necessary to identify co-infections with Paracoccidioides.
Myocarditis and pericarditis recovery following smallpox vaccine 2002–2016: A comparative observational cohort study in the military health system
Authors: Engler Renata J. M. , Montgomery Jay R. , Spooner Christina E. , Nelson Michael R. , Collins Limone C. , Ryan Margaret A. , Chu Clara S. , Atwood John E. , Hulten Edward A. , Rutt Ahlea A. , Parish Dacia O. , McClenathan Bruce M. , Hrncir David E. , Duran Laurie , Skerrett Catherine , Housel Laurie A. , Brunader Janet A. , Ryder Stephanie L. , Lohsl Connie L. , Hemann Brian A. , Cooper Leslie T. 
Published: May 2023

Objectives
(1) Characterize the initial clinical characteristics and long-term outcomes of smallpox vaccine-associated hypersensitivity myocarditis and pericarditis (MP) in United States service members. (2) Describe the process of case identification and adjudication using the 2003 CDC nationally defined myocarditis/pericarditis epidemiologic case definitions to include consideration of case-specific diversity and evolving evidence.

Background
Between 2002 and 2016, 2.546 million service members received a smallpox Vaccinia vaccine. Acute MP is associated with vaccinia, but the long-term outcomes have not been studied.

Methods
Records of vaccinia-associated MP reported to the Vaccine Adverse Event Reporting System by vaccination date were adjudicated using the 2003 MP epidemiologic case definitions for inclusion in a retrospective observational cohort study. Descriptive statistics of clinical characteristics, presentation, cardiac complications, and time course of clinical and cardiac recovery were calculated with comparisons by gender, diagnosis and time to recovery.

Results
Out of over 5000 adverse event reports, 348 MP cases who survived the acute illness, including 276 myocarditis (99.6% probable/confirmed) and 72 pericarditis (29.2% probable/confirmed), were adjudicated for inclusion in the long-term follow-up. Demographics included a median age of 24 years (IQR 21,30) and male predominance (96%). Compared to background military population, the myocarditis and pericarditis cohort had a higher percentage of white males by 8.2% (95% CI: 5.6, 10.0) and age <40 years by 4.2% (95% CI: 1.7,5.8). Long-term follow-up documented full recovery in 267/306 (87.3%) with 74.9% recovered in less than a year (median ~3 months). Among patients with myocarditis, the percentage who had a delayed time to recovery at time of last follow-up was 12.8% (95% CI: 2.1,24.7) higher in those with an acute left ventricular ejection fraction (EF) of ≤50% and 13.5% (95% CI: 2.4,25.7) higher in those with hypokinesis. Patient complications included 6 ventricular arrhythmias (2 received implanted defibrillators) and 14 with atrial arrhythmias (2 received radiofrequency ablation). Three of 6 patients (50%) diagnosed with cardiomyopathy had clinical recovery at their last follow-up date.

Conclusions
Hypersensitivity myocarditis/pericarditis following the smallpox vaccine is associated with full clinical and functional ventricular recovery in over 87% of cases (74.9% <1 year). A minority of MP cases experienced prolonged or incomplete recovery beyond 1 year.
The effect of isocaloric, energy-restrictive, KETOgenic diet on metabolism, inflammation, nutrition deficiencies and oxidative stress in women with overweight and obesity (KETO-MINOX): Study protocol
Authors: Drabińska Natalia , Romaszko Jerzy , White Paul 
Published: May 2023

Obesity is considered one of the biggest health problems of the 21st century, becoming a worldwide epidemic, leading to the development of many diseases and increasing the risk of premature death. The first step in reducing body weight is a calorie-restricted diet. To date, there are many different diet types available, including the ketogenic diet (KD) which is recently gaining a lot of attention. However, all the physiological consequences of KD in the human body are not fully understood. Therefore, this study aims to evaluate the effectiveness of an eight-week, isocaloric, energy-restricted, KD as a weight management solution in women with overweight and obesity compared to a standard, balanced diet with the same calorie content. The primary outcome is to evaluate the effects of a KD on body weight and composition. The secondary outcomes are to evaluate the effect of KD-related weight loss on inflammation, oxidative stress, nutritional status, profiles of metabolites in breath, which informs about the metabolic changes in the body, obesity and diabetes-associated parameters, including a lipid profile, status of adipokines and hormones. Notably, in this trial, the long-term effects and efficiency of the KD will be studied. In summary, the proposed study will fill the gap in knowledge about the effects of KD on inflammation, obesity-associated parameters, nutritional deficiencies, oxidative stress and metabolism in a single study.
ClinicalTrail.gov registration number: NCT05652972.
“Of course, drones delivering urgent medicines are necessary. But I would not use them until…” Insights from a qualitative study on users’ needs and requirements regarding the use of medical drones
Authors: Fink Franziska , Paulicke Denny , Grünthal Martin , Jahn Patrick 
Published: May 2023

Background
The current COVID-19 pandemic, demographic trends, and the increasing shortage of skilled workers pose major challenges for the care of people with and without care needs. The potential of drones as unmanned aerial vehicles in health care is being discussed as an effective innovative way of delivering much-needed medicines, especially in rural areas. Although the advantages are well known, the needs of the users have not yet been taken into account.

Methods
Online-based focus groups (via WebEx) were conducted with participants from different disciplines: nursing, pharmacy, physicians. Focus groups with COVID-19 patients were conducted face-to-face. The focus was primarily on potential problems and requirements of the users regarding the use of drones. Structured and contrastive snowball sampling has been deployed. The focus groups were audio recorded, transcribed by a transcription-company, and coded with the help of the program “f4analyse 2” for content (Elo et al. 2008).

Results
Especially during the pandemic situation, delays, and restrictions in the delivery of medicines have been noticed. All interview partners (patients, pharmacists, physicians, and nurses; n = 36 participants) see drones as useful in cases of limited mobility, time-critical medicines (rapid availability), emergencies, and disasters (e.g., floods), but also for the delivery of regular medicines in rural areas (e.g., for the treatment of chronic diseases). Moreover, only 16.7% of the participants have experiences with drones.

Discussion
Drone deliveries do not play a role in the health system yet despite their great importance, which is perceived as particularly evident in the pandemic situation. The results lead to the conclusion that this is mainly due to knowledge and application deficits, so that educational and advisory work is absolutely necessary. There is also a need for further studies that go beyond the scope of acceptance research to describing and evaluating concrete scenarios of drone delivery on the basis of a user-centered approach.
Millennial Fandom: Television Audiences in the Transmedia Age, Louisa Stein (2015)
Authors: Howell Linda 
Published: May 2023

Review of: Millennial Fandom: Television Audiences in the Transmedia Age, Louisa Stein (2015)
Iowa City, IA: University of Iowa Press, 224 pp.,
ISBN 978-1-60938-355-8, p/bk, $24.00
Straight Korean Female Fans and Their Gay Fantasies, Jungmin Kwon (2019)
Authors: Entrikin Kelsey 
Published: May 2023

Review of: Straight Korean Female Fans and Their Gay Fantasies, Jungmin Kwon (2019)
Iowa City, IA: University of Iowa Press, 236 pp.,
ISBN 978-1-60938-621-4, p/bk, $65.00
DIÁLOGO ENTRE A TECNOLOGIA SOCIAL DA MEMÓRIA, A HISTÓRIA ORAL E A FUNÇÃO DA HISTÓRIA
Authors: Venera Raquel Alvarenga Sena , Nart Gustavo Henrique Cardoso , Medina Bruna de Souza 
Published: May 2023

Este artigo busca discutir a relação entre as metodologias História Oral ea Tecnologia Social da Memória com ênfase na criação de objetos epistemológicos, na potencialização política de narrativas de memória e na função da História. A partir da exposição “Comunicação Sensível”, aponta a potência do discurso político das narrativas de vidas ao mesmo tempo em que discute a função epistemológica de produção de fontes de memória. O desafio é a partir da definição e das considerações acerca da História Oral de Vida, em Albert (1996; 2005) e Thompson (2006), aproximar da Tecnologia Social da Memória, construída pelo Museu da Pessoa (2009) e mapear, em diálogo comSzymczak (2018), a aproximação e a diferenciação dessas duas metodologias, refletindo também acerca da função da História em Rusën (2001). O artigo mostra como a exposição “Comunicação Sensível” traduz essas duas vertentes, quais sejam, a construção de fontes históricas e a função política da visibilidade da voz de sujeitos históricos.
Geometry of CMC surfaces of finite index
Authors: Meeks William H. , Pérez Joaquín 
Published: May 2023

Abstract
Given

r

0

>
0

{r}_{0}\gt 0

,

I
∈
N
∪

{

0

}

I\in {\mathbb{N}}\cup \left\{0\right\}

, and

K

0

,

H

0

≥
0

{K}_{0},{H}_{0}\ge 0

, let

X

X

be a complete Riemannian 3-manifold with injectivity radius

Inj

(

X

)

≥

r

0

\hspace{0.1em}\text{Inj}\hspace{0.1em}\left(X)\ge {r}_{0}

and with the supremum of absolute sectional curvature at most

K

0

{K}_{0}

, and let

M

↬

X

M\hspace{0.33em}\looparrowright \hspace{0.33em}X

be a complete immersed surface of constant mean curvature

H
∈

[

0
,

H

0

]

H\in \left[0,{H}_{0}]

and with index at most

I

I

. We will obtain geometric estimates for such an

M

↬

X

M\hspace{0.33em}\looparrowright \hspace{0.33em}X

as a consequence of the hierarchy structure theorem. The hierarchy structure theorem (Theorem 2.2) will be applied to understand global properties of

M

↬

X

M\hspace{0.33em}\looparrowright \hspace{0.33em}X

, especially results related to the area and diameter of

M

M

. By item E of Theorem 2.2, the area of such a noncompact

M

↬

X

M\hspace{0.33em}\looparrowright \hspace{0.33em}X

is infinite. We will improve this area result by proving the following when

M

M

is connected; here,

g

(

M

)

g\left(M)

denotes the genus of the orientable cover of

M

M

:

(1)
There exists

C

1

=

C

1

(

I
,

r

0

,

K

0

,

H

0

)

>
0

{C}_{1}={C}_{1}\left(I,{r}_{0},{K}_{0},{H}_{0})\gt 0

, such that

Area

(

M

)

≥

C

1

(

g

(

M

)

+
1

)

{\rm{Area}}\left(M)\ge {C}_{1}\left(g\left(M)+1)

.

(2)
There exist

C
>
0

C\gt 0

,

G

(

I

)

∈
N

G\left(I)\in {\mathbb{N}}

independent of

r

0

,

K

0

,

H

0

{r}_{0},{K}_{0},{H}_{0}

, and also

C

C

independent of

I

I

such that if

g

(

M

)

≥
G

(

I

)

g\left(M)\ge G\left(I)

, then

Area

(

M

)

≥

C

(

max

1
,

1

r

0

,

K

0

,

H

0

)

2

(

g

(

M

)

+
1

)

{\rm{Area}}\left(M)\ge \frac{C}{{\left(\max \left\{1,\frac{1}{{r}_{0}},\sqrt{{K}_{0}},{H}_{0}\right\}\right)}^{2}}\left(g\left(M)+1)

.

(3)
If the scalar curvature

ρ

\rho

of

X

X

satisfies

3

H

2

+

1

2

ρ
≥
c

3{H}^{2}+\frac{1}{2}\rho \ge c

in

X

X

for some

c
>
0

c\gt 0

, then there exist

A
,
D
>
0

A,D\gt 0

depending on

c
,
I
,

r

0

,

K

0

,

H

0

c,I,{r}_{0},{K}_{0},{H}_{0}

such that

Area

(

M

)

≤
A

{\rm{Area}}\left(M)\le A

and

Diameter

(

M

)

≤
D

{\rm{Diameter}}\left(M)\le D

. Hence,

M

M

is compact and, by item 1,

g

(

M

)

≤
A

/

C

1

−
1

g\left(M)\le A\hspace{0.1em}\text{/}\hspace{0.1em}{C}_{1}-1

.
Wer bietet mehr, oder: Wie eine Vielzahl Signaturen zustande kommt
Authors: Blortz Ulrich Ch. 
Published: May 2023

Zusammenfassung
Am Beispiel des Bonner Standortes von ZB MED – Informationszentrum Lebenswissenschaften, der früheren Zentralbibliothek der Landbauwissenschaft (ZBL) wird dargestellt, wie sich eine Vielzahl von verschiedenen Signaturenarten „historisch entwickelt“.
Physicochemical and biological properties of carvacrol
Authors: Gandova Vanya , Lazarov Anton , Fidan Hafize , Dimov Milen , Stankov Stanko , Denev Petko , Ercisli Sezai , Stoyanova Albena , Gulen Hatice , Assouguem Amine , Farah Abdellah , Ullah Riaz , Kara Mohammed , Bari Ahmed 
Published: May 2023

AbstractCarvacrol is a major component of many essential oils of the genusThymus, Satureja,andOriganum, determining their antimicrobial, antioxidant, and other properties. The aim of the present study was to investigate some physicochemical and biological properties of pure carvacrol. The surface tension and density were measured at six different temperatures (30, 40, 50, 60, 70, and 80°C). The surface tension values were between 53.11 and 60.38 mN/m, while density varied from 0.978 to 0.99 kg/m3. The antibacterial activity against seven pathogenic and conditionally pathogenic bacteria was investigated. The diameter of the inhibition zones was determined in the range of 3.9–4.9 mm. The antioxidant activity was determined by the oxygen radical absorbance capacity (1687.0 µmol TE/mL) method.