bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bevacizumab in recurrent WHO grades II–III glioma
Authors: Annakib Soufyan , Rigau Valérie , Darlix Amélie , Gozé Catherine , Duffau Hugues , Bauchet Luc , Jarlier Marta , Fabbro Michel 
Published: July 2023

PurposeThe management of recurrent WHO grades II–III (rGII–III) glioma is not well established. This study describes the clinical outcomes in patients who received bevacizumab as rescue treatment.MethodsIn this retrospective study, the main inclusion criteria were as follows: adult patients with histologicaly proved rGII–III glioma according 2016 WHO classification treated with bevacizumab from 2011 to 2019, T1 contrast enhancement on MRI. Efficacy was assessed using the high-grade glioma 2017 Response Assessment in Neuro-Oncology criteria. Progression-free survival (PFS) and overall survival (OS) were estimated using the Kaplan–Meier method.ResultsEighty-one patients were included (M/F ratio: 1.7, median age at diagnosis: 38 years) among whom 46 (56.8%) had an initial diagnosis of grade II glioma. Previous treatments included at least one surgical intervention, radiotherapy (98.8%), and ≥ 2 chemotherapy lines (64.2%). After bevacizumab initiation, partial response, stable disease, and progressive disease were observed in 27.2%, 22.2%, and 50.6% of patients. The median PFS and OS were 4.9 months (95% confidence interval [CI] 3.7–6.1) and 7.6 months (95% CI 5.5–9.9). Bevacizumab severe toxicity occurred in 12.3%. Twenty-four (29.6%) patients discontinued bevacizumab without radiological progression. Oligodendroglioma and age ≥ 38 years at diagnosis were more frequent in this subgroup (odds ratio = 0.24, 95% CI 0.07–0.84, p = 0.023 and 0.36, 95% CI 0.13–0.99, p = 0.042). Ten of these 24 patients were alive at 12 months and two patients at 8 years after bevacizumab initiation, without any subsequent treatment.ConclusionBevacizumab can be an option for heavily pretreated patients with rGII–III glioma with contrast enhancement. In our study, bevacizumab displayed prolonged activity in a subgroup of patients.
Formative experiences and psychological distance in the lives of contemporary environmentalists
Authors: Raja Urooj S. , Carrico Amanda R. 
Published: July 2023

IntroductionWe use the term “environmentalists” to describe the people who are highly and actively engaged and involved in environmental issues like climate change. Environmentalists consistently advocate, research, or volunteer to do the work needed to address environmental challenges. Factors that drive contemporary environmentalists remain understudied.MethodsWe, therefore, ask: what formative experiences drive environmentalists on climate change and other environmental problems at present? We frame this exploration through the significant life experiences (SLE) literature, which examines people and environmental pathways. We also ask: how do feelings of perceptual/actual distance or closeness to environmental threats and climate change shape a person’s decision to become an environmentalist? We anchor this query to the psychological distance (PD) literature that explores how people perceive external phenomena and the role distance plays in their conception. To answer both questions, we use qualitative methods and draw on 33 interviews with environmentalists involved in environmental protection work for an average of 91 h in the past 4 weeks.ResultsWe find that environmentalists spoke about several formative experiences broadly consistent with what has been documented in the SLE literature. Traumatic experiences were especially influential for our sample of environmentalists. Our findings also reveal that PD, especially social, plays a role in the lives of environmentalists.DiscussionStudy findings could help scholars and practitioners deepen their understanding of contemporary environmentalists. Practitioners, in particular, could use this knowledge to help environmentalists by providing them with tailored resources and support.
Safety climate perceived by pre-hospital emergency care personnel—an international cross-sectional study
Authors: Kosydar-Bochenek Justyna , Religa Dorota , Knap Małgorzata , Czop Marcin , Knap Bartosz , Mędrzycka-Dąbrowska Wioletta , Krupa Sabina 
Published: July 2023

IntroductionImproving patient safety is one of the most critical components of modern healthcare. Emergency medical services (EMS) are, by nature, a challenging environment for ensuring patient safety. It is fast-paced, physically dangerous, and highly stressful, requiring rapid decision-making and action. This can create risks not only for patients but also for employees. We assessed variations in perceptions of safety culture in prehospital emergency care among an international sample of paramedics and nurses.MethodsThe Emergency Medical Services Safety Attitudes Questionnaire (EMS-SAQ) was used for the study. The instrument measures six domains of safety culture in the workplace: teamwork climate, job satisfaction, safety climate, working conditions, stress recognition, and perceptions of management. A total of 1,128 EMS from 9 countries participated in this study.ResultsSafety Climate was 81.32/100 (SD 6.90), Teamwork Climate 84.14/100 (SD 8.74), Perceptions of Management 76.30/100 (SD 10.54), Stress Recognition 89.86/100 (SD 5.70), Working Conditions 81.07/100 (SD 9.75), and Job Satisfaction 70.71/100 (SD 7.21). There was significant variation in safety culture scores across countries for teamwork climate (TWC), working conditions (WC), and job satisfaction (JS). Among the individual variables (age, gender, level of education, and work experience), variations in safety culture scores were unaffected by age, gender, or work experience. Organizational characteristics: employment status and position type were linked to significant variations in safety culture domain scores.ConclusionParticipants’ perceptions of the patient safety climate were not particularly satisfactory, confirming that there is still a need to develop a culture of patient safety in prehospital emergency care.
PERBANDINGAN KELUHAN MUSKULOSKELETAL PADA MAHASISWA FAKULTAS KEDOKTERAN DENGAN DAN TANPA GANGGUAN SOSIAL MEDIA
Authors: M Idrus Baagil Fatma , Bustamam Nurfitri , Safira Lisa 
Published: July 2023

Pada pandemi COVID-19 sebagian besar aktivitas mahasiswa kedokteran dilaksanakan secara daring. Hal tersebut membuat mahasiswa berisiko mengalami gangguan sosial media dan keluhan muskuloskeletal. Penelitian ini bertujuan untuk mengetahui bagaimana perbandingan keluhan muskuloskeletal antara mahasiswa kedokteran dengan atau tanpa gangguan sosial media. Penelitian menggunakan desain potong lintang dan teknik stratified proportional random sampling pada mahasiswa kedokteran Universitas Pembangunan Nasional “Veteran” Jakarta tahun 2021. Instrumen penelitian yang digunakan adalah kuesioner karakteristik subjek, Nordic Body Map dan Social Media Disorder questionnaire. Hasil analisis didapatkan 32,8% dari 64 subjek mengalami gangguan sosial media. Bagian tubuh yang banyak mengalami keluhan adalah leher (47,6%), tengkuk (42,9%), punggung (52,4%), pinggang (61,9%), dan pergelangan tangan kanan (7%). Hasil uji Chi-square exact didapatkan perbedaan keluhan muskuloskeletal antara mahasiswa yang mengalami gangguan sosial media dan yang tidak mengalami gangguan sosial media (p = 0,001). Terdapat perbedaan keluhan pada leher dan pinggang antara mahasiswa yang mengalami gangguan sosial media dengan yang tidak mengalami gangguan sosial media (p < 0,05). Hasil penelitian ini menunjukkan perlunya self awareness terhadap keluhan fisik muskuloskeletal dan gangguan sosial media sehingga masalah tersebut dapat segera diatasi.
During the COVID-19 pandemic, most medical student activities were held online. These put students at risk for social media disorders and musculoskeletal complaints. This study aims to compare musculoskeletal complaints between medical students with or without social media disorders. The study used a cross-sectional design with a stratified proportional random sampling technique towards medical students of Universitas Pembangunan Nasional “Veteran” Jakarta in 2021. The research instruments used were the subject characteristics questionnaire, the Nordic Body Map, and the Social Media Disorder questionnaire. The results of the analysis showed that 32.8% of 64 subjects experienced social media disorders. The body parts that experienced the most complaints were the neck (47.6%), the nape (42.9%), the back (52.4%), the waist (61.9%), and the right wrist (7%). The results of the Chi-square exact test showed differences in musculoskeletal complaints between students who experienced social media disorders and those who did not experience social media disorders (p = 0.001). There are differences in complaints about the neck and waist between students who experience social media disorders and those who do not experience social media disorders (p<0.05). The results of this study indicate the need for self-awareness of musculoskeletal physical complaints and social media disorders so that these problems can be treated immediately.
ANALISA PENGARUH ANALISA JABATAN DAN ANALISA BEBAN KERJA TERHADAP KINERJA SUMBER DAYA MANUSIA PADA DINAS PEKERJAAN UMUM DAN PENATAAN RUANG PROVINSI SUMATERA UTARA
Authors: Pardosi Ananda , Andronicus Melkyory , Tumanggor Andi Bagus Rizky , Manurung Eva Rusvalina , Salunia Salunia , Sri Rahayu Sri Rahayu 
Published: July 2023

Penelitian ini bertujuan untuk meneliti mencari tahu lebih dalam mengenai Dinas Pekerjaan Umum dan Penataan Ruang Provinsi Sumatera Utara adalah sebuah organisasi pemerintahan yang bergerak menyelenggarakan perumusan dan pelaksanaan di bidang penyelenggaraan jalan sesuai dengan ketentuan perundang-undangan di bawah naungan Dinas Pekerjaan Umum (PU). Untuk mendapatkan sumber daya manusia yang paling tepat dan sesuai dengan kebutuhan organisasi agar mendapatkan kinerja yang maksimal dari sumber daya manusia tersebut, maka Dinas Pekerjaan Umum dan Penataan Ruang Provinsi Sumatera Utara menggunakan analisa jabatan dan analisa beban kerja. Dalam melakukan analisa jabatan, Dinas Pekerjaan Umum dan Penataan Ruang Provinsi Sumatera Utara menetapkan deskripsi kerja yang sesuai dengan jabatan yang akan diduduki dan spesifikasi kerja. Sementara pada analisa beban kerja yang dijalankan Dinas Pekerjaan Umum dan Penataan Ruang Provinsi Sumatera Utara ditetapkan bahwa beban kerja yang harus dipenuhi dalam satu bulan adalah 6000 menit jam kerja atau 22 hari kerja dalam sebulan. Tetapi yang terjadi, masih ada sumber daya manusia yang tidak memenuhi beban kerja tersebut, dimana yang paling signifikan terjadi pada bulan April dan Juni 2022 yaitu terdapat 38 dan 30 orang yang tidak memenuhi beban kerja. Maka perlu dilakukan analisa jabatan dan analisa beban kerja dengan melakukan pengujian-pengujian salah satunya Uji Koefisien Determinan menggunakan Spss maka diketahui nilai dari Abjusted R Square (Koefisien Determinan) sebesar 0,063 yang artinya pengaruh variabel independen (X) terhadap variabel dependen sebesar 6,3%.
PENGARUH KOMPETENSI KERJA, DISIPLIN KERJA DAN FLEKSIBILITAS KERJA TERHADAP KINERJA KARYAWAN DI ERA NEW NORMAL PADA PT. TORGANDA KANDIR MEDAN
Authors: Subakti Ripaldo , Rajagukguk Sri Meilin , Hutahaean Van Daniel , Nazmi Hendra , Fahmi Nur Augus 
Published: July 2023

Tujuan penelitian ini ialah untuk mengetahui Pengaruh Kompetensi Kerja, Disiplin Kerja Dan Fleksibilitas Kerja Terhadap Kinerja Karyawan Di Era New Normal Pada Pt. Torganda Kandir Medan. Penelitian ini menggunakan pendekatan kuantitatif dengan jenis penelitian eksplanatori. Direncanakan, penelitian ini akan dilaksanakan selama 3 bulan mulai dari November 2022 hingga Januari 2023 di PT. Torganda Kandir Medan, yang berlokasi di JL. Abdullah Lubis No.26, Babura, Kec. Medan Baru, Kota Medan, Sumatera Utara 20153. Populasi dalam penelitian ini adalah seluruh karyawan PT. Torganda Kandir Medan, dengan sampel yang diambil adalah seluruh karyawan tetap PT. Torganda Kandir Medan. Pengumpulan data dilakukan melalui penggunaan kuesioner yang akan didistribusikan kepada karyawan sebagai responden. Selain itu, wawancara juga dilakukan dengan karyawan PT. Torganda Kandir Medan. Metode ini
Digunakan peneliti untuk mendapatkan informasi tentang perusahaan berdasarkan laporan yang diberikan oleh perusahaan. Data primer dalam penelitian ini mencakup hasil wawancara dengan karyawan PT. Torganda Kandir Medan dan pengisian kuesioner yang diberikan kepada perusahaan tersebut. Sementara itu, sumber data sekunder melibatkan studi dokumentasi. Berdasarkan hasil penelitian dan pembahasan, secara parsial variabel Kompetensi Kerja memiliki pengaruh positif dan signifikan terhadap kinerja karyawan PT. Torganda Kandir Medan di era New Normal. Begitu pula, secara parsial variabel Disiplin Kerja juga memiliki pengaruh positif dan signifikan terhadap kinerja karyawan PT. Torganda Kandir Medan di era New Normal. Selain itu, secara parsial variabel Fleksibilitas Kerja juga memiliki pengaruh positif dan signifikan terhadap kinerja karyawan PT. Torganda Kandir Medan di era New Normal.
PENGARUH PERBEDAAN SUHU PEREBUSAN DAN KONSENTRAS NaOH TERHADAP KUALITAS BUBUK TULANG IKAN GABUS (Channa striata)
Authors: Cucikodana Yunita , Supriadi Agus , Purwanto Budi 
Published: July 2023

The purpose of this Â research was to observe the quality of snake head fish bone powder using different boiling Â temperature and NaOH concentration.The Factorial Randomized Block Design was used with two factors of treatment and 2 replications. The different boiling temperatures (60 0C, 650C, 700C) and three different NaOH concentrations (Control 0%, NaOH 2%, NaOH 4% and NaOH 6%). The parameters were yield, whiteness, density, Â solubilityÂ and calcium content. The result showed that the treatments significantly effected the yield (43.98%-97.47%), whiteness (47.6-58.48%) density (0.51â€“0.67 g/ml), solubility(11.38-23.76%) and calcium content (16.86-22.77%). Â Keyword :bone powder, snake head, calcium
The Influence of the Work Environment, Organizational Commitment, and Information Technology on Employee Performance at KSP CU Dharma Prima Kita Yogyakarta
Authors: Andi Andi , Kurniawan Ignatius Soni 
Published: July 2023

This study aims to determine the effect of the work environment, organizational commitment, and information technology on employee performance. The population used in this study were employees of KSP CU Dharma Prima Kita, Yogyakarta. This research is a quantitative study and primary data was taken using a questionnaire on 40 respondents taken from a saturated population and the answers were processed using multiple linear regression analysis. The results in this study state that the work environment, organizational commitment, and information technology partially have a positive effect on employee performance.
Estrategia pedagógica enfocada a la mitigación de impactos causados por agroquímicos en cultivos de aguacate hass (persea americana) en la vereda la cristalina (casabianca tolima)
Authors: Parra Maira Alejandra , Monje Ceballes Benigno , Montealegre Giraldo José Fernando 
Published: July 2023

La presente investigación titulada: estrategia pedagógica enfocada a la mitigación de impactos causados por agroquímicos en cultivos de aguacate Hass (Persea americana) en la vereda la cristalina (Casabianca - Tolima). Es un trabajo que resulta de la pregunta ¿Cómo sensibilizar por medio de una estrategia pedagógica a la comunidad de la vereda la cristalina sobre la contaminación causada por agroquímicos en el cultivo de aguacate Hass (Persea americana)?. El objetivo general de la investigación es, desarrollar una estrategia pedagógica sobre la huella ecológica que deja la utilización de agroquímicos en el cultivo de aguacate hass como medio de enseñanza para mitigar el impacto que tiene sobre el suelo. El enfoque de la investigación es cualitativo, el alcance es exploratorio y el diseño utilizado fue el de participación acción, el tipo de muestreó de casos-tipos, esta muestra se centra en la finca la Conga y el Rubí ubicadas en la misma vereda. Para la recolección de datos en el trabajo investigativo, se toma la técnica de entrevista utilizando una guía de entrevista semiestructurada con preguntas abiertas. Para las técnicas e instrumentos de recolección de información, se hacen personalmente las entrevistas a los parceleros y cultivadores. En la investigación se culmina con presentar la estrategia pedagógica de la forma teórico-práctica a los cultivadores en el mismo lugar de la investigación. El trabajo finaliza con recolectar información de resultados aplicando nuevamente otra entrevista para su análisis. De allí, se emite como producto algunas conclusiones y recomendaciones.
Expert Evaluation-Based Generation of Synonymic Sets for Sentiment Analysis
Authors: Гончаров А. Р. , Лысенкова С. А. , Назин А. С. 
Published: July 2023

представлен результат экспертной оценки машинного перевода онлайн-сервисом «Reverso Context» в задаче формирования синонимичных рядов. Данные ряды формируют кортежи слов, предназначенные для проведения процедуры анкетирования методом «наилучшее-худшее масштабирование» и расчёта коэффициентов эмоциональности слов в новом тональном словаре. Номинальные оценки экспертов были переведены в связанные ранги, на основании которых рассчитан коэффициент согласованности экспертов. Обработанные оценки экспертов показывают адекватность подобранного данным сервисом перевода.
this study presents the expert evaluation of machine translation by the Reverso Context online service as applied to the generation of synonymic sets. These sets are used for a ”best-worst” survey and estimation of emotionality levels to make a sentiment dictionary. The expert scores were converted into ranks. We also estimated the consistency index for the experts. The expert evaluations indicated that the machine translation offered by the online service is adequate.
Implementation of The Qur'an in Modern Science Learning
Authors: Mape Angel , Ardi Ardi , Andini Divi , Sakina Shalmita 
Published: July 2023

Alqur'an is a very perfect human guideline, because it regulates all aspects of human life, both worldly life including very small things and the afterlife. But unfortunately, the development of the times has led to the teachings of alqur'an and further away from the monitoring and implementation of the contents of alqur'an ‟in human life. From the perspective of Islamic science, Islamic science is used as a tool to gain knowledge about Allah, pleasure and closeness to Allah. Knowledge must be able to direct a Muslim in various ways and efforts to get close to Allah SWT. The method used in this research is the literature review method by looking for various relevant theoretical references. The data sources in this study are 10 articles obtained from the database Google Scholar and Google Scholar. This study aims to find out how the Implementation of alqur'an in Modern Science Learning. Based on the results of the literature review, it can be concluded that alqur'an plays a role in the advancement of science, especially science, both in Biology, Mathematics, Physics, Chemistry, Medicine, and other sciences. In the field of biology, alqur'an explains how the creation of humans, the creation of the heavens and the earth, the functions of the structures of living things (animals), etc. In the fields of mathematics, Algebra, Sets, Geometry and Measurement, Logic, Statistics and Estimation (estimates) are several concepts mathematics in the Qur'an, and in the field of chemistry alqur'an also explains how the creation of the universe. Thus, it seems clear that learning science cannot be separated from the verses of alqur'an.

Keywords : implementation,alqur'an,learning science
Impact of COVID-19 Pandemic on Routine Vaccination Coverage among Children of Age 15 to 23 Months in Lahore, Punjab, Pakistan
Authors: Khadim Hussain Komal , Danish Hasan , Ahmad Farah 
Published: July 2023

Background: The COVID-19 pandemic affected all socio-economic activities including the provision of routine vaccinations.
Objective: This study determined the effect of the COVID-19 pandemic on routine vaccination rates among children aged 15-23 months.
Methods: A cross-sectional study was conducted in Lahore, from April 2021 to November 2021. The study included 750 children aged 15 to 23 months from the District of Lahore. A structured questionnaire was used to collect data from the outpatient department of Services Hospital, Lahore after informed consent. The data was analyzed by using SPSS version 26. The p-value <0.05 was considered statistically significant.
Results: Among the study participants, 567 (75%) children had completed their routine vaccines according to the card. One hundred and eighty-three (24.2%) children were not fully vaccinated. Seven hundred and twenty-seven (96.2%) children had oral polio 1 (OPV I), while 693 (91.7%) had Pneumococcal 2 (PCV II), and 696 (92.1%) had taken the Pentavalent 1 vaccine. Measles 2 was received by only 604 (79.9%) children. Sixty-three (8.3%) mothers and caregivers were unaware of the need for vaccination. Twenty-seven (3.6%) mothers had no time to get their children vaccinated, and 27 (3.4%) were uninformed about their children’s vaccination appointments.
Conclusion: The vaccination rate was 36% lower among children of ages 15-23 months in the Lahore district compared to the pre-pandemic era.
Guillain-Barre Syndrome, Clinical Spectrum and Electrophysiological Sub Types: A Local Experience
Authors: Shamim Faryal , Safia Safia bano , Waqar Masooma , Numan Ahsan 
Published: July 2023

Background: Guillain-Barre syndrome is uncommon neurological disease that occurs in acute phase as generalized polyradiculo-neuropathy. It has multiple variants some of them being uncommon and rarely encountered.
Objective: The objective of the study was to determine the frequency and clinical characteristics of Guillain-Barre syndrome variants.
Methods: A cross-sectional study was carried out in neurology department, Mayo hospital from July to December 2022. Patients clinically diagnosed as Guillain-Barre syndrome by using Brighton criteria were included. All the patients underwent electro diagnostic procedures and they were categorized into five basic variants i.e., Acute motor axonal neuropathy, Acute motor sensory axonal neuropathy, acute inflammatory demyelinating polyradiculo-neuropathy, acute sensory axonal neuropathy and mixed variety acute polyradiculo-neuropathy.
Results: Out of total 85 patients, males were 56 (65.9%) and 29 (34.1%) were females. Adults were more affected with a mean age of 36±15.3. Frequency of acute motor axonal neuropathy (35.3%) was high followed by acute motor sensory axonal neuropathy (31.8%), mixed variety acute polyradiculo-neuropathy (16.5%), acute inflammatory demyelinating polyradiculo-neuropathy (12.9%) and acute sensory axonal neuropathy (3.5%) respectively.
Conclusion: Acute motor axonal neuropathy is frequently encountered Guillain-Barre syndrome variant in our setup. Also, the frequency of acute sensory axonal neuropathy and mixed variety acute polyradiculo-neuropathy has increased with a declining trend of acute inflammatory demyelinating polyradiculo-neuropathy.