bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bio‐Derived Fluorescent Carbon Dots for Metal Sensing and DNA Binding Applications
Authors: Daphne Jacinth Gracia K. , Sheeba Thavamani S. , Peter Amaladhas T. 
Published: January 2023

AbstractTunable optical and electronic properties of the fluorescent carbon dots have drawn significant research interests over the years mainly owing to their sensing and photocatalytic applications. In this work, highly fluorescent nitrogen doped carbon dots [N−CDs] have been synthesised from Quercus infectoria via hydrothermal treatment. The structural, optical properties and the surface functionalities of the synthesised N−CDs are analysed with the help of various analytical techniques. The spherical shaped N−CDs exhibit an average particle size of 5 nm. Dual turn‐on‐off fluorescent sensors have been developed to sense Fe(III) and cysteine with detection limit of 1.88×10−8 M and 7.8×10−5 M respectively. The synthesised N−CDs exhibited excellent sensitivity in the in vitro detection of Fe(III) in ferric citrate supplements with a detection limit of 1.43×10−7 M. Interaction between ct‐DNA and N−CDs with a binding constant of 1.32 (mg/mL)−1 indicates its potency in designing drugs. The fluorescent nature of the N−CDs envisions its application to image SKMEL cells and L6 cells. This work may be extended for the use of N−CDs for diverse applications including in vivo sensing.
Zn‐Incorporated Titanium Substrates with High Antibacterial Activity and Consecutive Release of Zinc
Authors: Lin Xing , Jin Kaihao , He Liyin , Zhi Hongfeng , Ying Yunhui , Wang Xiao , Wu Yinqiu , Zhang Jianfeng 
Published: January 2023

AbstractIn this work, Zn‐incorporated titanium substrate with nano network structures was built, and its antibacterial activity against the gram positive and negative bacteria was tested. Ti plate was successively treated by hot alkaline, Zn2+ion‐exchange, and ZnO nanoparticles deposit, where alkaline treated Ti plate (NTi), Zn2+exchanged Ti plate (NZTi), Zn2+/ZnO incorporated Ti plate (NZZTi) were correspondingly generated. ForEscherichia coli, the antibacterial percentage of NZTi and NZZTi after 24 h was 99.86 % and 99.98 %, while it was 99.95 % and 100 % forStaphylococcus aureus, respectively. The result disclosed that NZZTi have a bit better antibacterial activity than NZTi, which indicates that Zn2+shows fabulous antibacteria activity and the presence of ZnOnps can contribute the antibacterial ability of Ti plates, which agrees with result of NZZTi‐Cup antibacterial effect. The release tests of Zn2+after 8 days from NZZTi‐Cup disclosed that Zn‐incorporated Ti plate could consecutively release trace Zn ions.
Base‐Mediated N‐Acetylation of Anilines/Amines: Nitriles as a Surrogate of the Acetyl Group
Authors: Kumar Saurav , Agasti Nityananda , Singh Gajendra , Kumar Anil 
Published: January 2023

AbstractA base‐mediated protocol has been established for the N‐acetylation of anilines/amines at room temperature. Reaction utilizes acetonitrile as a solvent as well as a surrogate of the acetyl group. Apart from acetonitrile, trifluoroacetonitrile could also be utilized in the reaction. The advantages of the reactions are simple operation, transition‐metal‐free approach, short reaction time, high functional group tolerance, and gram‐scale synthesis, which show the reaction‘s utility. The developed strategy represents a valuable approach in synthetic organic chemistry.
Macrophage Polarization Induced by Bacteria‐Responsive Antibiotic‐Loaded Nanozymes for Multidrug Resistance‐Bacterial Infections Management
Authors: Zhu Xufeng , Guo Jiaqi , Yang Yonglan , Liu Jie 
Published: January 2023

AbstractInherited bacterial resistance and biofilm‐induced local immune inactivation are important factors in the failure of antibiotics to fight against bacterial infections. Herein, antibiotic‐loaded mesoporous nanozymes (HA@MRuO2‐Cip/GOx) are fabricated for overcoming bacterial resistance, and activating the local immunosuppression in biofilm microenvironment (BME). HA@MRuO2‐Cip/GOx are prepared by physical adsorption between ciprofloxacin (Cip) or glucose oxidase (GOx) and MRuO2 NPs, and modified with hyaluronic acid (HA). In vitro, HA@MRuO2‐Cip/GOx cleaves extracellular DNA (eDNA) to disrupt biofilm, thereby enhancing Cip kill planktonic bacteria. Furthermore, HA@MRuO2‐Cip/GOx can induce polarization and enhance phagocytosis of a macrophage‐derived cell line. More importantly, in vivo therapeutic performance confirms that HA@MRuO2‐Cip/GOx can trigger macrophage‐related immunity, and effectively alleviate MRSA‐bacterial lung infections. Accordingly, nanocatalytic therapy combined with targeted delivery of antibiotics could enhance the treatment of bacterial infections.
Extracellular Vesicles as Delivery Shippers for Noncoding RNA‐Based Modulation of Angiogenesis: Insights from Ischemic Stroke and Cancer
Authors: Pan Yongli , Liu Yuheng , Wei Wei , Yang Xinyu , Wang Zengguang , Xin Wenqiang 
Published: January 2023

AbstractIschemic stroke and systemic cancer are two of the leading causes of mortality. Hypoxia is a central pathophysiological component in ischemic stroke and cancer, representing a joint medical function. This function includes angiogenesis regulation. Vascular remodeling coupled with axonal outgrowth following cerebral ischemia is critical in improving poststroke neurological functional recovery. Antiangiogenic strategies can inhibit cancer vascularization and play a vital role in impeding cancer growth, invasion, and metastasis. Although there are significant differences in the cause of angiogenesis across both pathophysiological conditions, emerging evidence states that common signaling structures, such as extracellular vesicles (EVs) and noncoding RNAs (ncRNAs), are involved in this context. EVs, heterogeneous membrane vesicles encapsulating proteomic genetic information from parental cells, act as multifunctional regulators of intercellular communication. Among the multifaceted roles in modulating biological responses, exhaustive evidence shows that ncRNAs are selectively sorted into EVs, modulating common specific aspects of cancer development and stroke prognosis, namely, angiogenesis. This review will discuss recent advancements in the EV‐facilitated/inhibited progression of specific elements of angiogenesis with a particular concern about ncRNAs within these vesicles. The review is concluded by underlining the clinical opportunities of EV‐derived ncRNAs as diagnostic, prognostic, and therapeutic agents.
An Omniphobic Spray Coating Created from Hierarchical Structures Prevents the Contamination of High‐Touch Surfaces with Pathogens
Authors: Abu Jarad Noor , Rachwalski Kenneth , Bayat Fereshteh , Khan Shadman , Shakeri Amid , MacLachlan Roderick , Villegas Martin , Brown Eric D. , Soleymani Leyla , Didar Tohid F. 
Published: January 2023

AbstractEngineered surfaces that repel pathogens are of great interest due to their role in mitigating the spread of infectious diseases. A robust, universal, and scalable omniphobic spray coating with excellent repellency against water, oil, and pathogens is presented. The coating is substrate‐independent and relies on hierarchically structured polydimethylsiloxane (PDMS) microparticles, decorated with gold nanoparticles (AuNPs). Wettability studies reveal the relationship between surface texturing of micro‐ and/or nano‐hierarchical structures and the omniphobicity of the coating. Studies of pathogen transfer with bacteria and viruses reveal that an uncoated contaminated glove transfers pathogens to >50 subsequent surfaces, while a coated glove picks up 104 (over 99.99%) less pathogens upon first contact and transfers zero pathogens after the second touch. The developed coating also provides excellent stability under harsh conditions. The remarkable anti‐pathogen properties of this surface combined with its ease of implementation, substantiate its use for the prevention of surface‐mediated transmission of pathogens.
Mycosynthesis of Zinc Oxide Nanoparticles Exhibits Fungal Species Dependent Morphological Preference
Authors: Brady Nathan G. , O'Leary Shamus L. , Moormann Garrett C. , Singh Manish K. , Watt John , Bachand George D. 
Published: January 2023

AbstractFilamentous fungi can synthesize a variety of nanoparticles (NPs), a process referred to as mycosynthesis that requires little energy input, do not require the use of harsh chemicals, occurs at near neutral pH, and do not produce toxic byproducts. While NP synthesis involves reactions between metal ions and exudates produced by the fungi, the chemical and biochemical parameters underlying this process remain poorly understood. Here, the role of fungal species and precursor salt on the mycosynthesis of zinc oxide (ZnO) NPs is investigated. This data demonstrates that all five fungal species tested are able to produce ZnO structures that can be morphologically classified into i) well‐defined NPs, ii) coalesced/dissolving NPs, and iii) micron‐sized square plates. Further, species‐dependent preferences for these morphologies are observed, suggesting potential differences in the profile or concentration of the biochemical constituents in their individual exudates. This data also demonstrates that mycosynthesis of ZnO NPs is independent of the anion species, with nitrate, sulfate, and chloride showing no effect on NP production. These results enhance the understanding of factors controlling the mycosynthesis of ceramic NPs, supporting future studies that can enable control over the physical and chemical properties of NPs formed through this “green” synthesis method.
Spatial Control of Substitutional Dopants in Hexagonal Monolayer WS2: The Effect of Edge Termination
Authors: Zhang Tianyi , Liu Mingzu , Fujisawa Kazunori , Lucking Michael , Beach Kory , Zhang Fu , Shanmugasundaram Maruda , Krayev Andrey , Murray William , Lei Yu , Yu Zhuohang , Sanchez David , Liu Zhiwen , Terrones Humberto , Elías Ana Laura , Terrones Mauricio 
Published: January 2023

AbstractThe ability to control the density and spatial distribution of substitutional dopants in semiconductors is crucial for achieving desired physicochemical properties. Substitutional doping with adjustable doping levels has been previously demonstrated in 2D transition metal dichalcogenides (TMDs); however, the spatial control of dopant distribution remains an open field. In this work, edge termination is demonstrated as an important characteristic of 2D TMD monocrystals that affects the distribution of substitutional dopants. Particularly, in chemical vapor deposition (CVD)‐grown monolayer WS2, it is found that a higher density of transition metal dopants is always incorporated in sulfur‐terminated domains when compared to tungsten‐terminated domains. Two representative examples demonstrate this spatial distribution control, including hexagonal iron‐ and vanadium‐doped WS2 monolayers. Density functional theory (DFT) calculations are further performed, indicating that the edge‐dependent dopant distribution is due to a strong binding of tungsten atoms at tungsten‐zigzag edges, resulting in the formation of open sites at sulfur‐zigzag edges that enable preferential dopant incorporation. Based on these results, it is envisioned that edge termination in crystalline TMD monolayers can be utilized as a novel and effective knob for engineering the spatial distribution of substitutional dopants, leading to in‐plane hetero‐/multi‐junctions that display fascinating electronic, optoelectronic, and magnetic properties.
The Collision between g‐C3N4 and QDs in the Fields of Energy and Environment: Synergistic Effects for Efficient Photocatalysis
Authors: Chen Yongxi , Cheng Min , Lai Cui , Wei Zhen , Zhang Gaoxia , Li Ling , Tang Chensi , Du Li , Wang Guangfu , Liu Hongda 
Published: January 2023

AbstractRecently, graphitic carbon nitride (g‐C3N4) has attracted increasing interest due to its visible light absorption, suitable energy band structure, and excellent stability. However, low specific surface area, finite visible light response range (<460 nm), and rapid photogenerated electron–hole (e−–h+) pairs recombination of the pristine g‐C3N4 limit its practical applications. The small size of quantum dots (QDs) endows the properties of abundant active sites, wide absorption spectrum, and adjustable bandgap, but inevitable aggregation. Studies have confirmed that the integration of g‐C3N4 and QDs not only overcomes these limitations of individual component, but also successfully inherits each advantage. Encouraged by these advantages, the synthetic strategies and the fundamental of QDs/g‐C3N4 composites are briefly elaborated in this review. Particularly, the synergistic effects of QDs/g‐C3N4 composites are analyzed comprehensively, including the enhancement of the photocatalytic performance and the avoidance of aggregation. Then, the photocatalytic applications of QDs/g‐C3N4 composites in the fields of environment and energy are described and further combined with DFT calculation to further reveal the reaction mechanisms. Moreover, the stability and reusability of QDs/g‐C3N4 composites are analyzed. Finally, the future development of these composites and the solution of existing problems are prospected.
Multi‐Mechanism Antibacterial Strategies Enabled by Synergistic Activity of Metal–Organic Framework‐Based Nanosystem for Infected Tissue Regeneration
Authors: Xie Wenjia , Chen Junyu , Cheng Xinting , Feng Hao , Zhang Xin , Zhu Zhou , Dong Shanshan , Wan Qianbing , Pei Xibo , Wang Jian 
Published: January 2023

AbstractDrug‐resistant bacterial infection impairs tissue regeneration and is a challenging clinical problem. Metal–organic frameworks (MOFs)‐based photodynamic therapy (PDT) opens up a new era for antibiotic‐free infection treatment. However, the MOF‐based PDT normally encounters limited photon absorbance under visible light and notorious recombination of photogenerated holes and electrons, which significantly impede their applications. Herein, a MOFs‐based nanosystem (AgNPs@MOFs) with enhanced visible light response and charge carrier separation is developed by modifying MOFs with silver nanoparticles (AgNPs) to improve PDT efficiency. The AgNPs@MOFs with enhanced photodynamic performance under visible light irradiation mainly disrupt bacteria translation process and the metabolism of purine and pyrimidine. In addition, the introduction of AgNPs endows nanosystems with chemotherapy ability, which causes destructive effect on bacterial cell membrane, including membrane ATPase protein and fatty acids. AgNPs@MOFs show excellent synergistic drug‐resistant bacterial killing efficiency through multiple mechanisms, which further restrain bacterial resistance. In addition, biocompatible AgNPs@MOFs pose potential tissue regeneration ability in both Methicillin–resistantStaphylococcusaureus(MRSA)‐related soft and hard tissue infection. Overall, this study provides a promising perspective in the exploration of AgNPs@MOFs as nano antibacterial medicine against drug‐resistant bacteria for infected tissue regeneration in the future.
Freestanding Block Copolymer Membranes with Tunable Pore Sizes Promoted by Subnanometer Nanowires
Authors: Ouyang Wanyue , Zhang Simin , Wang Xun 
Published: January 2023

AbstractBlock copolymers (BCPs) have enduring appeal for its intriguing assembly behaviors. Nevertheless, the unsatisfactory mechanical properties of BCPs make it a problem to fabricate freestanding membranes and hindered practical applications. Herein, a freestanding membrane with tunable pore size is prepared simply by co‐assembly of BCPs and subnanometer nanowires (SNWs), combining the abundant function of BCPs and prominent mechanical properties of SNWs. Benefited from synergy of the components and the hierarchical structure, the tensile strength of composite membrane is promoted by two orders of magnitude compared to that of BCPs. With the columnar pores aligning vertically to surfaces and the pore size regulated by processing conditions, the membranes exhibit precise size‐selected effect in ultrafiltration of Au nanoparticles (Au NPs) and can distinct NPs with diameter difference as tiny as 5 nm, demonstrating the promising prospect in separation technology and even widespread fields.
Negatively Charged Holey Titania Nanosheets Added Electrolyte to Realize Dendrite‐Free Lithium Metal Battery
Authors: Luo Geng , Liu Dongqing , Zhao Jie , Hussain Arshad , Raza Waseem , Wu Yanyan , Liu Fude , Cai Xingke 
Published: January 2023

AbstractElectrolyte modulation and electrode structure design are two common strategies to suppress dendrites growth on Li metal anode. In this work, a self‐adaptive electrode construction method to suppress Li dendrites growth is reported, which merges the merits of electrolyte modulation and electrode structure design strategies. In detail, negatively charged titania nanosheets with densely packed nanopores on them are prepared. These holey nanosheets in the electrolyte move spontaneously onto the anode under electrical field, building a mesoporous structure on the electrode surface. The as‐formed porous electrode has large surface area with good lithiophilicity, which can efficiently transfer lithium ion (Li+) inside the electrode, and induce the genuine lithium plating/stripping. Moreover, the negative charges and nanopores on the sheets can also regulate the lithium‐ion flux to promote uniform deposition of Li metal. As a result, the symmetric and full cells using the holey titania nanosheets containing electrolyte, show much better performance than the ones using electrolyte without holey nanosheets inside. This work points out a new route for the practical applications of Li‐metal batteries.
Phase‐Modulated Multidimensional Perovskites for High‐Sensitivity Self‐Powered UV Photodetectors
Authors: Zhang Xinyu , Li Ziqing , Yan Tingting , Su Li , Fang Xiaosheng 
Published: January 2023

Abstract2D Ruddlesden‐Popper perovskites (PVKs) have recently shown overwhelming potential in various optoelectronic devices on account of enhanced stability to their 3D counterparts. So far, regulating the phase distribution and orientation of 2D perovskite thin films remains challenging to achieve efficient charge transport. This work elucidates the balance struck between sufficient gradient sedimentation of perovskite colloids and less formation of small‐n phases, which results in the layered alignment of phase compositions and thus in enhanced photoresponse. The solvent engineering strategy, together with the introduction of poly(3,4‐ethylene‐dioxythiophene):polystyrene sulfonate (PEDOT:PSS) and PC71BM layer jointly contribute to outstanding self‐powered performance of indium tin oxide/PEDOT:PSS/PVK/PC71BM/Ag device, with a photocurrent of 18.4 µA and an on/off ratio up to 2800. The as‐fabricated photodetector exhibits high sensitivity characteristics with the peak responsivity of 0.22 A W−1 and the detectivity up to 1.3 × 1012 Jones detected at UV‐A region, outperforming most reported perovskite‐based UV photodetectors and maintaining high stability over a wide spectrum ranging from UV to visible region. This discovery supplies deep insights into the control of ordered phases and crystallinity in quasi‐2D perovskite films for high‐performance optoelectronic devices.
Symmetry‐Breaking Induced Dipole Enhancement for Efficient Spiro‐Type Hole Transporting Materials: Easy Synthesis with High Stability
Authors: Xu Jianbin , Xiong Qiu , Huang Xiaofeng , Sun Pingping , Zhou Qin , Du Yitian , Zhang Zilong , Gao Peng 
Published: January 2023

AbstractSpiral cores are crucial for designing efficient hole transporting materials (HTMs) for perovskite solar cells (PSCs), owing to their no‐planar 3D architecture, high thermal stability, good solubility, and beneficial solid‐state morphology. A lack of facile synthetic procedures for the spiral core limited the development of novel and stable spiral HTMs. In this regard, a one‐step reaction is adopted to produce several novel acceptor‐embedded spiral cores containing electron‐withdrawing carbonyl group embedded orthogonal spiral conformation. After coupling with triphenylamine donors, symmetry‐breaking spiral HTMs with uneven charge distribution can be obtained, bearing the advantages of adjustable dipole moment and enhanced structural stability. A combined theoretical and experimental study shows that the HTM with a stronger dipole moment can easily adsorb on the surface of perovskite via electrostatic potential, and the closer distance promoted facile hole transfer from perovskite to HTMs. In the end, PSCs based on strongly polarized spiro‐BC‐OMe achieved efficient hole extraction and thus an improved fill factor, promoting a power conversion efficiency (PCE) of 22.15%, and a module‐based PCE of 18.61% with an active area of 16.38 cm2. This study provides a new avenue for designing HTMs with strong dipole moments for efficient PSCs.
Interfacial Roughness Enhanced Gel/Elastomer Interfacial Bonding Enables Robust and Stretchable Triboelectric Nanogenerator for Reliable Energy Harvesting
Authors: Jing Titao , Wang Shuchang , Yuan Haiyuan , Yang Yujue , Xue Ming , Xu Bingang 
Published: January 2023

AbstractGel‐based triboelectric nanogenerator (TENG) has demonstrated promising potentials in stretchable electronics owing to gel electrodes’ intrinsic softness, stretchability, and conductivity. However, delamination between gel and elastomer layers in deformations remains a considerable challenge for gel‐based TENG, which most often induces structure failure. Herein, gels are regarded as adhesives and further effectively enhances interfacial bonding strength by a rough interface in adhesives’ view, which exploits gels’ liquid‐to‐solid transformation. This method just needs surface roughness of elastomer, which avoids chemical modification. Moreover, this method is effective to both organogel with good stickiness and hydrogel with weak stickiness, demonstrating wide applicability to different gels. Owing to the tough gel/elastomer interfacial bonding, TENG‐Rough largely solves delamination problem under various deformations and the corresponding output performances of TENG‐Rough are also maintained, implying a robust stretchable TENG device for reliable energy harvesting. This work demonstrates a general and facile method to enhance interfacial bonding in an adhesives’ way, which provides a view for addressing delamination problem in gel‐based TENGs and other kinds of gel‐based devices.
In Situ Coupling of Carbon Dots with Co‐ZIF Nanoarrays Enabling Highly Efficient Oxygen Evolution Electrocatalysis
Authors: Hong Qiang , Wang Yingming , Wang Ruirui , Chen Ziliang , Yang Hongyuan , Yu Kai , Liu Yang , Huang Hui , Kang Zhenhui , Menezes Prashanth W. 
Published: January 2023

AbstractMetal‐organic frameworks (MOFs) are regarded as one promising class of precatalysts for electrocatalytic oxygen evolution reaction (OER), yet most of them suffer from poor conductivity and lack of coordinatively unsaturated metal sites, which hinders the fast electrochemical reconstruction and thus a poor OER activity. To address this issue, a unique heterocomposite has been constructed by in situ inserting carbon dots (CDs) into cobalt‐based zeolitic imidazolate framework (Co‐ZIF) nanosheet arrays (Co‐ZIF/CDs/CC) in the presence of carbon cloth (CC) via one‐pot coprecipitation for alkaline OER. Benefiting from the synergism between CDs and Co‐ZIF subunits such as superior conductivity, strong charge interaction as well as abundant metal sites exposure, the Co‐ZIF/CDs/CC exhibits an enhanced promotion effect for OER and contributes to the deep phase transformation from CDs‐coupled Co‐ZIF to CDs‐coupled active CoOOH. As expected, the achieved Co‐ZIF/CDs/CC only requires an overpotential of 226 mV to deliver 10 mA cm−2 in 1.0 M KOH, which is lower than that of Co‐ZIF/CC and superior to most previously reported CC‐supported MOF precatalysts. Moreover, it can also maintain a large current density of 100 mA cm−2 for 24 h with negligible activity decay.