bluuebunny/crossref_metadata_2025_split huggingface dataset:
Supuestos, distancias y apropiación de la tecnología en la atención institucional de la salud
Authors: Lemus Alcántara Sergio 
Published: January 2025

La atención de la salud es una actividad institucionalizada bajo rectoría del Estado. La política pública actual ofrece beneficios circunscriptos al avance científico y el uso de tecnología por su potencial para resolver problemas de gran complejidad. Sin embargo, en los hospitales públicos, se observa la distancia entre el discurso y la concreción de la atención, cuyo epítome es la praxis humana. Este trabajo se deriva de un proyecto de investigación del Programa de Maestría y Doctorado en Ciencias Médicas, Odontológicas y de la Salud de la Universidad Nacional Autónoma de México (UNAM). Utiliza el método etnográfico en el contexto clínico. Los hallazgos abren la discusión sobre los alcances y las repercusiones del uso de la tecnología en el contexto clínico. A la fecha, el uso de la tecnología en la atención es tema de investigación en el Departamento de Historia y Filosofía de la Medicina de la UNAM, bajo la coordinación del Dr. Alfredo Paulo Maya.
Influence of Seed Priming, Plant Geometry and Conjunctive Use of Fertilizers, FYM and Vermicompost on Productivity and Economics of Green Gram (Vigna radiata L.)
Authors: Birla Jinendra , Pandey Santosh 
Published: January 2025

Background: Nutrients requirement of crops can easily be met by the application various fertilizers alone but in long run their continuous use deteriorate soil health and may retard the productivity of crops also. Further cost escalation and timely availability of fertilizers and other inputs lead to uneconomic production. Integrated nutrient management (INM) practices including reduced levels of fertilizers with locally available organic sources of plant nutrients, low cost and no cost inputs may be answer to the problems. Very meagre work has been done in past on different aspects on green gram crop. Present study aimed at evaluating and quantify the performance of summer green gram (Vigna radiata L.) crop as affected by seed hydropriming, plant geometry and nutrient applications through fertilizers, FYM, vermicompost and their combinations for maximizing the productivity and economic viability. Methods: The low cost seed hydropriming, no cost treatments of 2 plant geometries of (i) G1 (30´10 cm) and (ii) G2 (30´20 cm) and 5 treatments of integrated nutrient management (INM) practices (N) viz; (i) N1 (20+40+20 kg NPK/ha (RDF), (ii) N2 (100% RDF equivalent FYM), (iii) N3(100% RDF equivalent vermicompost) (iv) N4(50% RDF from fertilizer+50% RDF equivalent FYM) and (v) N5 (50% RDF from fertilizer+50% RDF equivalent vermicompost) were evaluated in field experiments using split-split plot design having 3 replications. Result: The main conclusion is that practices of seed hydropriming and planting geometry of 30´10 cm proved superior for realizing maximum productivity and profitability. Integrated application of fertilizer equivalent to 50% of recommended dose of fertilizers (RDF) coupled with 50% nutrients through organic sources like farmyard manure and or vermicompost (treatments N4 and N5) proved most effective over organic sources alone (FYM and vermicompost through treatments N2 and N3) and 100% RDF through fertilizers (N1) for summer green gram cultivation on sustainable basis. The results of the present work will be useful for majority of farmers particularly pulse crops growers to bridge the gap between present level of productivity and potentially realizable productivity of moong bean crop on cost effective and sustainable basis.
Performance of mud crab farming in natural seed-based apartment systems with various pretransport holding durations
Authors: Atul Hayati Mira , Effendi Irzal , Hadiroseyani Yani , Budiardi Tatag 
Published: January 2025

Farming mud crabs (Scylla serrata) in Indonesia generally use seeds from natural habitats, which are caught, held, and transported dry to the farming location. The crabs are held for several days while waiting for consumers. This study analyzed the impact of pre-transport holding times (one, three, and five days) with four replications and an average initial weight of 73.60 ± 12.53 g on the physiological condition and production performance of farming mud crabs in an apartment system. The crabs were transported dry from Muara Gembong, Bekasi Regency, West Java, to the IPB Fisheries and Marine Observation Station (IFMOS) Ancol, North Jakarta, DKI Jakarta, for three hours. The crabs were farming in apartment boxes with a recirculation system for 14 days. The results showed that the crabs experienced severe gill damage indicated by the lysis of gill cuticles and low survival rates, especially after five days of pre-transport holding. The crabs experienced stress in all treatments, as indicated by high glucose levels above 30 mg/dL. The best survival rate was found in the one-day pre-transport holding time, with a value of 87.50% at the holding location and 95% at the farming location. In conclusion, a one-day pre-transport holding time provides better physiological conditions and production performance for mud crab farming in an apartment system.

Keywords: crab, gills, natural catch, stress

ABSTRAK

Budidaya kepiting bakau (Scylla serrata) di Indonesia umumnya menggunakan benih dari alam, yang ditangkap, ditampung, dan kemudian di transportasi kering ke lokasi budidaya. Penampungan kepiting berlangsung beberapa hari sambil menunggu konsumen. Penelitian ini menganalisis dampak lama waktu penampungan pratransportasi (satu, tiga, dan lima hari) dengan empat ulangan dan bobot rata-rata awal 73,60 ± 12,53 g, terhadap kondisi fisiologi dan kinerja produksi kepiting bakau yang dibudidayakan dalam sistem apartemen. Kepiting di transportasi kering dari Muara Gembong, Kabupaten Bekasi, Jawa Barat, ke IPB fisheries and marine observation station (IFMOS) Ancol, Jakarta Utara, DKI Jakarta, selama tiga jam. Kepiting dibudidayakan pada boks apartemen dengan sistem resirkulasi selama 14 hari. Hasil penelitian menunjukkan bahwa kepiting mengalami kerusakan insang yang parah ditunjukkan dengan lisisnya kutikula insang dan tingkat kelangsungan hidup rendah, terutama setelah lima hari lama penampungan. Kepiting mengalami stres dalam semua perlakuan, yang ditunjukkan oleh tingginya kadar glukosa di atas 30 mg/dL. Tingkat kelangsungan hidup terbaik yakni pada lama waktu penampungan satu hari, dengan nilai 87,50% di lokasi penampungan dan 95% di lokasi budidaya. Kesimpulannya, lama waktu penampungan satu hari pratransportasi memberikan kondisi fisiologi dan kinerja produksi budidaya kepiting bakau sistem apartemen yang lebih baik.
Kata kunci: insang, kepiting, stres, tangkapan alam
Peluang Bisnis Kopi bagi Masyarakat Desa Serdang Wetan, Tangerang
Authors: Alexandra Yoanita , Situmorang Ringkar , Choirisa Septi Fahmi 
Published: January 2025

Kopi adalah salah satu minuman populer di Indonesia yang dapat dinikmati oleh berbagai macam kalangan. Selain itu, kopi telah menjadi bagian dari kehidupan dan budaya sehari-hari masyarakat Indonesia, dimana meningkatkan jumlah bisnis warung kopi di Indonesia. Bisnis warung kopi di Indonesia di nilai memiliki prospek bisnis yang bagus, dan keuntungan bersih yang tinggi. Berdasarkan pertimbangan kemudahan dalam pembuatan bisnis kopi sederhana, dan tingginya profit margin, maka pelatihan kopi dengan cara manual diberikan untuk Desa Serdang Wetan. Kegiatan ini bekerja sama dengan BUMDES (Badan Usaha Milik Desa) Serdang Tirta Kencana. Desa Serdang Wetan telah memiliki warung kopi sederhana yang dikelola oleh Karang Taruna setempat.. Adapun tujuan dari PKM ini adalah untuk membantu masyarakat Desa Serdang Wetan didalam memulai dan melanjutkan usaha bisnis warung kopi sederhana dengan berfokus kepada pelatihan coffee manual brew. PKM ini diharapkan dapat memberikan manfaat di masa depan bagi masyarakat desa Serdang Wetan yang ingin mempunyai usaha mikro kuliner di wilayahnya. Metode pengabdian dilaksanakan secara langsung di Desa Serdang Wetan.
Perancangan Konsep Kreatif Video Profil Desa Rancagong Sebagai Sarana Pengembangan Potensi Desa
Authors: Tanrere Rezki Gautama , Alfayadh Mohammad Dody , Ramadhani Syarurie , Taufiqulhakim Attirmidzi Irzan 
Published: January 2025

Desa Rancagong yang berlokasi 12 km di sebelah Barat Daya Kota Tangerang tepatnya di Kecamatan Legok memiliki potensi dalam menunjang aktivitas ekonomi desa. Mayoritas desa yang memiliki mata pencaharian tampah bambu dan kuliner tradisional khas Indonesia memiliki sejumlah UMKM unggulan yang sudah berjalan cukup lama. Selain itu, Desa Rancagong memiliki keindahan alam seperti area pesawahan dan mata air yang berpotensi sebagai tempat wisata. Namun permasalahan utama yang dialami Desa Rancagong adalah minimnya infomasi mengenai identitas desa tersebut pada khalayak luas. Hal tersebut disebabkan oleh keterbatasan modal, sumber daya manusia, hingga pengelolaan informasi melalui marketing yang buruk, sehingga berdampak pada kegiatan promosi wisata maupun produk-produk UMKM tidak berjalan dengan baik dan kurang dikenal oleh masyarakat luas. Melalui masalah tersebut, solusi yang dapat diberikan adalah perancangan dan pembuatan video profil desa. Video profil desa merupakan suatu proyek yang penting dalam memperkenalkan dan mempromosikan keunikan desa kepada dunia luar. Video profil dapat membantu meningkatkan kesadaran masyarakat tentang potensi desa dan menarik minat para investor dan wisatawan untuk berkunjung ke desa, selain itu video profil dapat dijadikan sebagai suatu dokumentasi sejarah hingga prestasi yang telah dicapai oleh Desa Rancagong. Agar kualitas video profil desa dapat berlangsung dengan baik, maka dilakukan metode kualitatif melalui survei, wawancara, observasi, studi eksisting dan studi literatur, serta dilakukuan metode perancangan visual secara sistematis melalui berbagai aspek seperti penyusunan script, storyboard,lighting, editingdan lainnya dalam 4 tahapan yaitu riset data, pra produksi, produksi hingga pasca produksi. Harapan besar, melalui perancangan dan pembuatan video profil Desa Rancagong, dapat memperkenalkan dan menambah ketertarikan masyarakat luas dengan meningkatnya kesadaranakan keindahan alam serta beragam potensi produk UMKM yang menarik Desa Rancagong, selain itu dapat pula membantu peningkatan perekonomian dan kesejahteraan masyarakat Desa Rancagong.
Exploring the impact of elevated pH and short maceration on the deterioration of red wines: physical and chemical perspectives
Authors: Nascimento Alves Carlos Artur , Camarão Telles Biasoto Aline Camarão Telles , Da Silva Nunes Grace , Oliveira do Nascimento Hélio , Ferreira do Nascimento Ronaldo , Gomes Oliveira Inglides , Coelho de Souza Leão Patrícia , Barros de Vasconcelos Lucicléia 
Published: January 2025

This study explored the impact of high pH and short maceration on red wines' physical and chemical traits and stability. Specifically, wines from Petit verdot, Merlot, Malbec and Tempranillo grapes, harvested in a tropical wine-producing region, were analysed. A consistent maceration period of 96 hours was applied in all vinification trials. After six months of bottling, parameters such as colour, acetaldehyde levels, higher alcohols and phenolic compounds were assessed. The findings highlighted significant impacts of grape pH on chemical stability, influenced by the phenolic profile of each grape variety. The short maceration period reduced phenolic compound extraction in high-pH musts, leading to decreased antioxidant potential and chemical stability. Critical indicators included colorimetric parameters, acetaldehyde and free SO₂ content. Acetaldehyde levels were strongly correlated with free SO₂ consumption and colour variations, signifying oxidative processes. Wines with higher concentrations of (+)-catechin, procyanidins and monomeric anthocyanins exhibited enhanced stability, while the presence of hydroxycinnamic acids was associated with oxidative changes. Caffeic acid emerged as a potential marker of oxidative stress, particularly in grapes from warmer climates. To improve the stability of wines made from high-pH grapes, extended maceration times or increased SO₂ dosages may be required.
Analyzing trends and suggested instructional strategies for Geometry education: Insights from Uganda Certificate of Education-Mathematics Examinations, 2016-2022
Authors: Ndungo Issa , Akugizibwe Edwin , Balimuttajjo Sudi 
Published: January 2025

Geometry education plays a pivotal role in fostering analytical, spatial, and problem-solving skills among students. Nonetheless, there is still a problem with how well geometry training in Ugandan schools accomplishes these objectives and this is evident in the Uganda Certificate of Education (UCE) examinations. To close this gap, a comprehensive examination of data taken from Uganda National Examinations Board (UNEB) reports covering the years 2016 to 2022 was carried out; with an emphasis on candidates’ performance, the study looks at common geometric ideas, pinpoints areas of weakness for candidates, and assesses response quality. This study's content analysis reveals notable variations in the quality of responses to various mathematics areas, with geometry consistently having the largest percentage of poor responses. Interestingly, in most areas, attempt levels positively correlate with response quality; but, in the case of geometry, this correlation reverses, suggesting that learners in this domain confront different problems. These problems include using geometric principles for problem-solving, combining algebraic and geometric concepts, and spatial visualization. The study advocates for using technology, active and problem-based learning; as these approaches provide opportunities for experiential learning, and conceptual knowledge reinforcement to learners. All this will support ongoing attempts to enhance mathematics education, particularly in the field of geometry, within the Ugandan context.
Spatio-temporal analysis of wetland loss in the lower Mekong River Basin based on surface water detection datasets and machine learning
Authors: Hiraga Yusuke , Aoki Mayu , Kazama So 
Published: January 2025

Abstract

Wetland loss and degradation is a major global issue in which its detailed estimation of spatio-temporal distribution will be a key for understanding the dynamics and subsequent impact assessment studies. This study aimed to estimate the spatio-temporal distributions of wetland loss, analyze its geographical characteristics, and quantify the likelihood of loss occurrence for existing wetlands in the lower Mekong River Basin in Cambodia. Using the global surface water detection datasets, the spatiotemporal distribution of wetland loss with high resolution (30m) over the entire study area (140km×210km) during 1984–2021 was estimated. Statistically significant differences were found in the distance from urban areas and distance from river channels for the existing wetlands and lost wetlands as of 2021, in which the lost wetlands tend to locate closer to urban areas. Subsequent Land Use/Land Cover after the wetland loss was found to be mainly croplands (72.2%) in the study area. Though our estimate overall agrees with the recent global-scale estimate, our estimate resulted in notable ratio of rangelands (11.3%), which represents the unique characteristics of floodplain wetlands in the lower Mekong River Basin. The Random Forest and Light GBM algorithms-based wetland loss prediction models resulted in good statistical evaluation metrics. In both models, the distance from river channels was found to be the most important feature for classifying existing wetlands and lost wetlands. Application of the developed models successfully provided the map of likelihood of wetland loss for existing wetlands in the study area.
ATAC-seq Guided Interpretable Machine Learning Reveals Cancer-Specific Chromatin Features in Cell-free DNA
Authors: Gunarathna Sakuntha , Nagornyuk Aerica , Belabbaci Nazim , Nguyen Regina , Ganai Sabha , Lemke Tabatha , Garry Cassy , Saotome Mika , Wang Xusheng , Takaku Motoki 
Published: January 2025

Abstract

Cell-free DNAs (cfDNAs) are DNA fragments found in blood. In healthy individuals, cfDNAs are primarily derived from immune cells, while in cancer patients, a significant fraction of cfDNAs originates from cancerous cells. These cancer-derived cfDNAs contain specific mutations, making cfDNA analysis a promising diagnostic biomarker. Recent studies have revealed that epigenetic information, such as DNA methylation and nucleosome positioning, is retained in cfDNAs, enhancing the accuracy of cell-of-origin predictions. This study aims to characterize the chromatin architecture preserved in cfDNAs by looking at nucleosomal DNA enrichment. Nucleosome fragments from both breast and pancreatic cancer patients are significantly enriched in open chromatin regions. A differential enrichment was observed between healthy donors and cancer patients at cell type-specific ATAC-seq peaks. Leveraging this pattern of open chromatin enrichment, we enhanced the prediction accuracy for identifying breast cancer-derived cfDNA through machine learning. Our analysis pipeline provides an interpretable machine learning platform that effectively detects cancer-specific nucleosome enrichment in cfDNAs.
Proteomics-based aging clocks in midlife and late-life and risk of dementia
Authors: Sedaghat Sanaz , Park Saeun , Walker Rob , Wang Shuo , Liu Jialing , Hughes Timothy , Sabayan Behnam , Tang Weihong , Coresh Josef , Pankow James , Walker Keenan , Casanova Ramon , Dubin Ruth , Deo Rajat , Rotter Jerome , Wood Alexis , Ganz Peter , Lutsey Pamela , Guan Weihua , Prizment Anna 
Published: January 2025

Abstract

Background: Biological age can be quantified by composite proteomic scores, called aging clocks. We investigated whether biological age acceleration (a discrepancy between chronological and biological age) in midlife and late-life is associated with cognitive function and risk of dementia.
Methods: We used two population-based cohort studies: Atherosclerosis Risk in Communities (ARIC) Study and Multi-Ethnic Study of Atherosclerosis (MESA). Proteomics-based aging clocks (PACs) were created in ARIC at midlife (mean age: 58 years, n=11,758) and late-life (mean age: 77 years, n=4,934) using elastic net regression models in two-thirds of dementia-free participants and validated in the remaining one-third of participants. Age acceleration (AA) was calculated as residuals after regressing PACs on chronological age. We validated the midlife PAC in the MESA cohort (mean age: 62 years, n=5,829). We used multivariable linear and Cox proportional hazards regression to assess the association of AA with cognitive function and dementia incidence, respectively.
Results: In ARIC, every five years AA was associated with lower global cognitive function: difference: -0.11, 95% confidence interval (CI): -0.16, -0.06) using midlife AA and difference: -0.17, CI: -0.23, -0.12 using late-life AA. Consistently, midlife AA was associated with higher risk of dementia (hazard ratio [HR]: 1.20 [CI: 1.04, 1.36]) and more prominently when using late-life AA (HR: 2.14 [CI:1.67, 2.73]). Similar findings were observed in the MESA study: every five years AA was associated with lower global cognitive function (difference: -0.08 [CI: -0.14, -0.03]) and higher risk of dementia (HR:1.23 [CI: 1.04, 1.46]).
Conclusion: Accelerated biological age – as defined by the plasma proteome – is associated with lower cognitive function and predicts a higher risk of dementia in midlife and more prominently in late-life.
Photobiomodulation with 650 nm Wavelength Mediates Endoplasmic Reticulum-Mitochondria Contact and Ameliorates Lipotoxicity in NAFLD via Mfn2/PERK/CHOP Signaling
Authors: Yao Min , Jiang Zhixuan , Wu Shan , Zhou Shengzhe , Zheng Hongjie , Bai Yubing , Zhang Yiqiu 
Published: January 2025

Abstract

The disruption of mitochondria associated membranes (MAMs) is involved in the pathogenesis of non-alcoholic fatty liver disease (NAFLD) by modulating endoplasmic reticulum stress (ERS) and mitochondrial malfunction induced by lipotoxicity. Photobiomodulation (PBM), as a non-invasive physical therapy, has been demonstrated to improve cellular metabolim in various diseases. Here we found that PBM with 650 nm ameliorated lipid accumulation and liver injury in high-fat-diet-fed mice. Moreover, MAMs integrity was restored in liver tissues of NAFLD after PBM. Correspondingly, PBM enhanced mitochondria-ER colocalization and improved mitochondrial homeostasis in fatty-acid-treated HepG2 cells. Mechanically, Mfn2 expression was selectively elevated by PBM, accompanied by downregulation of PERK, p-PERK, and CHOP. The beneficial effects of PBM were diminished by Mfn2 knockdown, while PERK activity regulated mitochondrial function without altering MAMs formation. Thus, PBM relieves lipotoxicity in NAFLD by enhancing MAMs integrity via the Mfn2/PERK/CHOP pathway. Our findings may provide evidence for noninvasive physical light therapeutics for lifestyle-related metabolic diseases.
Current carbon policies and emerging emission control technologies in the dairy supply chain
Authors: Wang Bei , Meng Fanyu , Wang Weijun , Wang Guofeng , Sun Chuanwang , Yang Zhijie , Wang Yadong , Han Haoying , Meng Yi , He Jian , Wang Yanbo , Liao Maolin , Wu Bobo , Sun Baoguo 
Published: January 2025

Abstract

Addressing the dynamic changes in the carbon footprint (CF) of the dairy industry to meet the diverse demands of different countries and achieve the global net-zero emission target presents a significant challenge. This study integrates a systematic scoping of CF and reduction strategies, with a policy analysis utilizing Term Frequency–Inverse Document Frequency (TF-IDF) statistics to provide a comprehensive assessment of current efforts to mitigate CF in the dairy industry. Across 29 countries, the CF of dairy production ranges from 0.57 kg CO₂-eq/kg FPCM (Norway) to 5.85 kg CO₂-eq/kg FPCM (Tanzania). Mitigation strategies are implemented across the entire dairy supply chain, with a primary focus on the milk production stage. Among the six countries analyzed over a 10-year period, New Zealand demonstrated the highest policy effectiveness, largely due to measures targeting feeding practices and dairy cattle breeding. This article offers an in-depth evaluation of CF reduction in the dairy sector, integrating environmental, technological, and policy dimensions.