bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hospital admission after primary care consultation for community-onset lower urinary tract infection: a cohort study of risks and predictors using linked data
Authors: Aryee Anna , Rockenschaub Patrick , Robson John , Priebe Marian , Ahmed Zaheer , Fhogartaigh Caoimhe Nic , Ball David , Hayward Andrew , Shallcross Laura 
Published: May 2023

BackgroundUrinary tract infections (UTIs) are a common indication for antibiotic prescriptions, reductions in which would reduce antimicrobial resistance (AMR). Risk stratification of patients allows reductions to be made safely.AimTo identify risk factors for hospital admission following UTI, to inform targeted antibiotic stewardship.Design and settingRetrospective cohort study of East London primary care patients.MethodHospital admission outcomes following primary care consultation for UTI were analysed using linked data from primary care, secondary care, and microbiology, from 1 April 2012 to 31 March 2017. The outcomes analysed were urinary infection-related hospital admission (UHA) and all-cause hospital admission (AHA) within 30 days of UTI in primary care. Odds ratios between specific variables (demographic characteristics, prior antibiotic exposure, and comorbidities) and the outcomes were predicted using generalised estimating equations, and fitted to a final multivariable model including all variables with aP-value <0.1 on univariable analysis.ResultsOf the 169 524 episodes of UTI, UHA occurred in 1336 cases (0.8%, 95% confidence interval [CI] = 0.7 to 0.8) and AHA in 6516 cases (3.8%, 95% CI = 3.8 to 3.9). On multivariable analysis, increased odds of UHA were seen in patients aged 55–74 years (adjusted odds ratio [AOR] 1.49) and ≥75 years (AOR 3.24), relative to adults aged 16–34 years. Increased odds of UHA were also associated with chronic kidney disease (CKD; AOR 1.55), urinary catheters (AOR 2.01), prior antibiotics (AOR 1.38 for ≥3 courses), recurrent UTI (AOR 1.33), faecal incontinence (FI; AOR 1.47), and diabetes mellitus (DM; AOR 1.37).ConclusionUrinary infection-related hospital admission after primary care consultation for community-onset lower UTI was rare; however, increased odds for UHA were observed for some patient groups. Efforts to reduce antibiotic prescribing for suspected UTI should focus on patients aged <55 years without risk factors for complicated UTI, recurrent UTI, DM, or FI.
AS RELAÇÕES DE CLASSE NOS CANTEIROS DE OBRAS BRASILEIROS
Authors: Costa Luciano Rodrigues 
Published: May 2023

Este artigo trata do funcionamento do mercado de trabalho no setor da construção de uma pequena cidade de Minas Gerais. Com base numa etnografia das práticas de trabalho e da gestão da mão de obra num canteiro de tamanho médio, o autor busca mostrar como os imperativos técnicos e organizacionais combinam-se com lógicas de relações de classe para organizar as práticas de contratação, de remuneração e de demissão. Demonstra-se que, visando a uma gestão eficiente e a um controle eficaz sobre o processo de trabalho, se desenvolve, paralelamente aos mecanismos institucionalizados do mercado, proteções informais para o estabelecimento de relações de lealdade e de confiança com os trabalhadores. A hipótese principal aqui discutida é tomada de empréstimo a Alain Morice, que havia sugerido, nos anos 1990, que as relações hierárquicas e a exploração da mão de obra nos canteiros se explicam em parte pelo desprezo por esses trabalhadores manuais sem qualificação advindos das zonas rurais.
Adsorption Of Clomid Drug On Activated Carbon And Zinc Oxide Surfaces
Authors: Hawraa K. Al-Husseini  
Published: May 2023

The research included study the adsorption of Clomid drug on the
surface of activated carbon and zinc oxide. Many of parameters were
studied which affect the adsorption process such as temperature, weight of
adsorbent, equilibrium time, initial concentration and effect of pH.
Activated carbon and zinc oxide were used as a model adsorbent in the
experiments. We found that increased of temperature (30-50) °C followed
by increased in adsorption capacity experiments were done at 30 °C and
showed that the optimum weight of activated carbon was (0.15 g) while for
zinc oxide was (0.1g), equilibrium time was (150 min) for the two
adsorbents. The adsorption capacity of the two adsorbents increased with
increasing initial concentration of drug, In addition, the experiments
showed that the (3-7) pH was the best medium of the adsorption process.
Semantic Segmentation of Foggy Scenes Based on Progressive Domain Gap Decoupling
Authors: Wang Ziquan , Zhang Yongsheng , Ma XianZheng , Yu Ying , Zhang ZhenChao , Jiang Zhipeng , Cheng Binbin 
Published: May 2023

<p>Robust Semantic Foggy Scene Segmentation (SFSS) is crucial for the security of autonomous driving. However, the blurring of images caused by fog increases the difficulty of recognition and makes annotation of foggy scene images more expensive, resulting poor performance when recognizing entities in the fog. Currently, many methods use domain adaptation to transfer segmentation knowledge from clear scenes to foggy ones. But these method are often ineffective due to the large domain gap between different cities' styles and the quality degradation of images caused by fog. The latest research has attempted to introduce an intermediate domain to decouple the domain gap and gradually complete the semantic segmentation of foggy scenes, but the exploration of the intermediate domain information is often insufficient. To solve these problems, we first analyze the self-training in domain adaptation and propose the concept of <em>"label reference value"</em>. We prove that the higher the total label reference value, the easier the self-training performance gets improved. With this precondition, we can reasonably split the original problem into two-stage domain adaptation. In each stage, the <em>"label reference value" </em>can be controlled and maximized. Specifically, the first stage only process the style gap between source domain and the intermediate domain, and the second stage process the fog gap. The fog gap includes: (1) real fog gap between the intermediate domain and target domain; (2) the synthetic fog gap between clear source domain and synthetic foggy source domain. This allows the model to make full use of <em>"label reference value"</em> and gradually develop good semantic segmentation skills for foggy scenes. Our approach significantly outperforms the baseline algorithm on all the mainstream SFSS benchmarks, with good generalization ability demonstrated in other adverse scenes such as rain and snow. We also compare our method with latest large segmentation models, which shows that our method has more robust performance in the foggy scenes. </p>
Utilizing Compost Soil Conditioner in Beach Sand Soil as a Palm Oil (Elaeis guineensis Jacq) in Pre-nursery Media
Authors: Suryanti Sri , Firman Syah Ryan , Al Hafish Ichan 
Published: May 2023

The objective of this study was to assess the effect of the type and dose of compost on the growth of oil palm seedlings in pre nursery with coastal sandy soil. The other objective is to know the effect of the type of compost on the growth of oil palm seedlings in pre nursery with coastal sandy soil. Lastly, the study examines the right dose of compost that provides the best growth of oil palm seedlings in pre nursery with coastal sandy soil. The experimental design was set in a factorial completely randomized design (CRD) consisting of two factors from April to June 2020 at the Tridharma Research Station Faculty of Agriculture, INSTIPER. The first factor is the type of compost which consists of 2 levels, Lamtoro compost, and vermicompost. The second factor is the dose of compost consisting of 4 levels: control (without compost), 50 gr compost/polybag, 75 gr compost/polybag, and 100 gr compost/polybag. The research data were analyzed using analysis of variance (α =0,05), and if there was a significant effect, it was continued with the Duncan multiple range test ( α = 0,05). Parameters observed included seedling height, total leaf, leaf width, stem diameter, shoot dry weight, root dry weight, root length, and total roots. The results showed that no combination of types and doses of compost significantly affected the growth of oil palm seedlings in pre-nursery. Using vermicompost can significantly increase oil palm seedlings' leaf area and root dry weight. Using compost at a dose of 50 g/polybag increased seedling height, stem diameter, and root dry weight in pre-nursery of oil palm seedlings.
Tolerance of Upland Rice Genotypes from Deli Serdang North Sumatra to Drought Stress Condition
Authors: Chaniago Noverina Chaniago , Setia Budi Rahmad , Nurhayati Nurhayati , Gunawan Indra Gunawan 
Published: May 2023

Drought is the main problem that is often faced in upland rice cultivation in the dry land. Therefore, drought-tolerant rice varieties are needed, but until now, the number is very limited. It is crucial to produce drought-tolerant rice because Indonesia has a relatively sizeable dry land of 148 million ha. This study aimed to obtain a genotype of upland rice that is tolerant to drought with high productivity and can be developed in the dry land. This research was then continued with drought tolerance testing by giving water below field capacity in a greenhouse. This study was in a factorial form using a Split Plot Design, with the main plot of drought stress treatment consisting of tree levels, namely water availability field capacity water, field capacity water, and field capacity water. The sub-plots were four genotypes of upland rice from Deli Serdang North Sumatra consisting of Sialus, Arias, Silayur, Sirabut and one drought-tolerant variety for comparison is Inpago11. The observed variables included plant height, chlorophyll content, number of tillers, number of productive tillers, age of flowering, harvest period, grain weight per clump, and weight of 100 grains. The heaviest drought stress (FCW) caused a significant decrease in plant height, number of tillers per clump, number of productive tillers, and grain weight per clump and extended the flowering and harvesting ages. Based on the tolerance index criteria, it was found that the Silayur genotype was more tolerant to drought stress than the other upland rice genotypes.
PENDEKATAN BALANCED SCORECARD DARI PERSPEKTIF PELANGGAN DI INSTALASAI FARMASI RUMAH SAKIT
Authors: Hidayati Ika Ratna , Rahman Miandi Akhmad Aldy , Yunita Sendi Lia 
Published: May 2023

Instalasi farmasi adalah unit pelaksana fungsional yang menyelenggarakan kegiatan pelayanan kefarmasian di Rumah Sakit. Balanced Scorecard merupakan satu sistem terintegrasi dari manajemen kinerja yang menyertakan ukuran capaian keuangan dan non-keuangan. Pendekatan Balanced Scorecard belum pernah dilakukan pada IFRSU Karsa Husada Batu sehingga perlu dilakukan untuk membantu meningkatkan kinerja IFRS. Bertujuan mengukur Kinerja Instalasi Farmasi Rumah Sakit Karsa Husada Batu berdasarkan perspektif pelanggan dengan indikator kepuasan pelanggan dan tingkat pertumbuhan pelanggan menggunakan Balanced Scorecard.. Penelitian ini menggunakan metode deskriptif dengan pendekatan cross sectional. Pengambilan sampel menggunakan metode non probability sampling dan teknik purposive sampling. Jumlah sampel indikator kepuasan pelanggan sebanyak 95 responden, Pertumbuhan pelanggan diambil dari jumlah resep yang masuk ke IFRSU Karsa Husada Batu pada periode Tahun 2020-2021. Hasil penelitian pada perspektif pelanggan indikator kepuasan pelanggan dengan metode Servqual mendapatkan nilai mendapatkan hasil rata-rata kenyataan lebih rendah daripada rata-rata harapan sehingga memiliki nilai kesenjangan negatif oleh sebab itu pelanggan merasa belum puas dengan kinerja IFRSU Karsa Husada Batu. Analisis tingkat kepuasan berdasarkan indeks kepuasan memiliki hasil puas dan masuk kriteria “Baik”. Analisis indikator pertumbuhan pelanggan pada tahun 2020 memiliki persentase sebesar 97% dan tahun 2021 sebesar 98%, dari hasil analisis dapat dikatakan baik karena mengalami kenaikan persentase tiap tahun. Dapat disimpulkan kinerja IFRSU Karsa Husada Batu cukup baik pada indikator pertumbuhan, namun perlu perbaikan serta evaluasi kinerja pada indikator kepuasan pelanggan.
IN SILICO DESIGN OF B-CELL EPITOPE BASED PEPTIDE VACCINE FOR ZIKA VIRUS
Authors: Sumadi Firasti AN , Ariadne Annisa ZS , Jamil Ahmad Shobrun , Muchlisin M. Artabah , Rachmawati Hidajah 
Published: May 2023

Zika virus infection attracted the attention of the medical community since it is transmitted by the Aedes mosquito and humans act as hosts. The disease affects fetal development and causes severe neurodevelopmental disorders, such as GBS (Guillain-Barre Syndrome), and CZS (Congenital Zika Syndrome) in pregnant women, including congenital microcephaly, and fetal death. Therefore, a vaccine is needed for prevention. Epitope-based peptide vaccines have advantages in terms of both selectivity and safety. The use of computational methods is a cost-efficient way of developing vaccines. This research aims to look at conserved areas and see the phylogenetic tree of the zika virus E protein sequences obtained from various countries, to see the most immunogenic epitope notifications of the ZIKV E protein sequence using the in-silico method, to see the potential for the most immunogenic epitopes of protein sequences. Zika virus as a vaccine candidate through the use of in silico. This study was using a descriptive observational study using in-silico tools for Zika virus peptide vaccine candidates. Some software and websites that were used are MEGA-X, IEDB, VaxiJen 2.0, BLASTp NCBI. From the 41 sequences that have been collected, 3 epitope candidates had antigenic properties and also passed the similarity test so the potential to develop a peptide vaccine; SLGLDCE, ETDENRAKVEVTPNSPRAEATLG, and AHAKRQ. Keywords: Vaccine, Peptide, Epitope, Zika Virus, In Silico
Formulasi Dan Evaluasi Sediaan Fisik Sediaan Serum Wajah Ekstrak Beras Merah (Oryza Nivara L.)
Authors: Sarifah Siti 
Published: May 2023

Dampak yang dapat ditimbulkan radikal bebas terutama dari paparan UV sinar matahari pada kulit wajah membuat produksi kolagen menurun, kulit kasar, kusam dan mulai muncul kerutan. Untuk mencegah dampak radikal bebas pada kulit wajah, dapat digunakan sediaan kosmetik beras merah yang dapat diformulasikan dalam bentuk serum wajah. Penelitian bertujuan untuk mnentukan formulasi, mengevaluasi sifat fisik serum wajah ekstrak beras merah dan menguji aktivitas antioksidan dari ekstrak beras merah. Formula serum mengandung ekstrak beras merah dengan konsentrasi 0,5%, 1% dan 2%. Gelling agent yang digunakan merupakan Hyropropyl Metylcellullose (HPMC) dengan variasi 1%, 0,8% dan 0,5%. Fromua serum dievaluasi sifat fisik meliputi pH, viskositas dan daya sebar. Uji DPPH digunakan untuk menguji aktivitas antioksidan dari ekstrak beras merah. Hasil uji evaluasi fisik sediaan serum menujukkan pH 5,5 ± 0,01 FI); 5,2 ± 0,2 (FII); dan 4,8 ± 0,01 (FIII). Viskositas untuk masing-masing formula adalah 4.527 ± 54,44 (FI); 3.582 ± 23,81 (FII) dan 2.900 ± 36,01 (FIII). Sedangkan daya sebar memberikan hasil 6,63 ± 0,15 (FI); 6,77 ± 0,06 (FII); dan 7,83 ± 0,06 (FIII). Uji antioksidan menunjukkan bahwa serum ekstrak beras merah memiliiki aktivitas sebagai antioksidan sedang dengan nilai 132,37. Formula II menjadi formula terbaik karena memiliki sifat fisik yang baik yang memenuhi persyaratan kriteria serum wajah ekstrak beras merah dan memiliki aktivitas antioksidan.
UJI TOKSISITAS AKUT EKSTRAK ETANOL DAUN TEMPUYUNG (Sonchus arvensis L.) PADA MENCIT BETINA DENGAN METODE FIXED DOSE
Authors: Amal Surya 
Published: May 2023

ABSTRAKTempuyung (Sonchus arvensis L.) adalah tumbuhan dari famili Asteraceae yang sering digunakan sebagai obat diuretik, batu ginjal, batu empedu, bengkak, asma, penurun kadar kolesterol, bronchitis dan pada penelitian sebelumnya menunjukkan efektivitasnya sebagai obat antihiperurisemia. Potensi pemanfaatannya sebagai bahan baku obat perlu didukung dengan uji keamanan. Penelitian yang dilakukan bertujuan untuk mengetahui toksisitas akut dari ekstrak etanol daun tempuyung ditinjau dari gejala klinis, berat badan, indeks organ, perubahan makropatologi, gambaran LD50 dan klasifikasi toksisitas akut ekstrak etanol daun tempuyung (Sonchus arvensis L.) pada mencit (Mus musculus) betina. Uji toksisitas akut dilakukan secara oral dengan menggunakan metode fixed dose dimana satu kelompok terdiri dari 5 ekor mencit betina. Dosis yang digunakan ialah 5 mg/kg BB, 50 mg/kg BB, 300 mg/kg BB, 2000 mg/kg BB, dan dilanjutkan ke uji batas 5000 mg/kg BB. Hasil dari penelitian ini ialah pada uji pendahuluan ditemukan adanya gejala toksisitas berupa gejala klinis mulai dari dosis 5 mg/kg BB sampai 2000 mg/kg BB walaupun tidak terdapat kematian pada hewan coba. Pada uji utama ditambahkan uji batas 5000 mg/kg BB dimana terdapat 80% mencit yang mati setelah 24 jam. Berdasarkan hasil penelitian disimpulkan bahwa ekstrak etanol daun tempuyung (Sonchus arvensis L.) mempunyai kisaran LD50 > 2000 mg/kg BB dengan klasifikasi sedikit toksik terhadap hewan uji mencit (Mus musculus) betina. Kata kunci: Toksisitas akut, Sonchus arvensis L., Metode fixed dose.
UJI ANALGETIKA MADU MURNI HASIL FERMENTASI BAWANG PUTIH TUNGGAL TERHADAP MENCIT (Mus musculus) JANTAN
Authors: Kunaedi Aan 
Published: May 2023

Honey has a variety of beneficial compounds, one is a flavonoid that can inhibit the pain enzyme namely cyclooxygenase. Klanceng honey is one of kind honey that is easily found in Indonesia and is unique cause honey comes from various plants that make it easy to cultivate. Besides honey, another natural ingredient that is popular with the antioxidant compound is garlic. It is known that the single garlic in the antioxidant compound is higher than the common garlic. The study is intended to identify the analgesic effect of fermented pure honey with single garlic in male mice. The research hypothesis is that H0= fermented pure honey with single garlic hasn’t an analgesic effect in mice and H1 = fermented pure honey with single garlic has an analgesic effect in male mice. Used 5 treatment groups where each mouse is induced by acetic acid. The group consists of negative control (aqua dest 0,5 ml), positive control (ibuprofen 0,65mg/20g BB), Treatment I (fermented honey 1 week 50% 37mg/20g BB), Treatment II (fermented honey 2 weeks 50% 37mg/20g BB) and Treatment III (pure honey 50% 37mg/20g BB). The result, fermented Klanceng Honey with single garlic with a dose of 37mg/20gBB 50% has an analgesic effect, especially those fermented in 2 weeks. If fermented honey of 2 weeks compared with 1-week fermentation and pure honey, it has a surplus: a)high-protection numbers; b)the lower average of writhings numbers and c)longer onset of writhings than 1-week fermentation.
KAJIAN FITOKIMIA PIGMEN WARNA UNGU DAN PROFIL ANTIOKSIDAN PADA EKSTRAK BUNGA HARENDONG (Melastoma malabatrichum L.)
Authors: Suhendy Hendy , Astuti Nita , Gustaman Firman 
Published: May 2023

Bunga harendong (Melastoma malabatrichum L.) merupakan salah satu tanaman sebagai sumber pigmen alami yang berkontribusi terhadap zat warna ungu. Pigmen warna ungu yang terdapat pada tanaman salah satunya bersumber dari antosianin dan diketahui bahwa secara farmakologis antosianin memberikan aktivitas antioksidan. Penelitian ini bertujuan untuk mengetahui pigmen warna ungu pada beberapa ekstrak dan menentukan aktivitas antioksidan secara kualitatif dan kuantitatif ekstrak terpilih. Serbuk simplisia bunga harendong diekstraksi dengan maserasi bertingkat menggunakan pelarut yang berbeda kepolaran dan ditambahkan dengan pelarut asam klorida 1%. Pengujian ekstrak dengan monitoring pigmen warna ungu dan memberikan aktivitas antioksidan secara kualitatif menggunakan kromatografi lapis tipis dan pengujian kuantitatif antioksidan menggunakan metode spektrofotometri UV-Vis dengan reagen DPPH. Data IC50 yang diperoleh dianalisis secara statistik menggunakan SPSS dengan metode independent T-Test. Pigmen warna ungu sebagai flavonoid yang memberikan aktivitas antioksidan secara kualitatif hanya terdapat pada ekstrak etil asetat dengan nilai Rf masing-masing sebesar 0,14 dan 0,84. Rataan nilai IC50 pada ekstrak etil asetat dan vitamin C secara berturut-turut adalah 4,54 ppm dan 2,85 ppm. Secara analisis statistik kedua nilai tersebut berbeda signifikan (p<0,05). Pigmen warna ungu sebagai flavonoid terdapat pada ekstrak etil asetat bunga harendong yang memberikan aktivitas antioksidan dengan kategori sangat kuat. Kata Kunci : Antioksidan; Bunga Harendong; Pigmen Warna Ungu
Counseling on the Potential of Platelet Growth Factor as a Biological Agent to Overcome Osteoarthritis Disorders at Ar-Rasyid Hospital Palembang Indonesia
Authors: Hidayat Rachmat 
Published: May 2023

Growth factor is a cytokine that plays a role in triggering a series of inhibition of inflammatory processes and triggers repair of joint cartilage which acts as a shock absorber. However, the current phenomenon shows that patients are still very hesitant to take advantage of the potential of platelet growth factor as a modality for the treatment of OA. The aspect of patient ignorance related to the potential of this modality is believed to be the reason for the lack of interest in OA patients utilizing this therapeutic modality. This community service aims to increase aspects of knowledge of OA patients about the potential, benefits and possible risks of using platelet growth factor through the process of counseling and education for OA patients at Ar-Rasyid Hospital Palembang Indonesia. This counseling activity was carried out on outpatients at the polyclinic of Ar-Rasyid Hospital Palembang Indonesia. There was an increase in the response knowledge score after counseling on the potential growth factor of platelets to overcome OA, with p<0.05. The results of the study also showed that there was an increase in aspects of attitude and behavior to choose the modality of platelet growth factor therapy after thecounseling process, with p < 0.05. Counseling activities are effective in improving aspects of knowledge and patient behavior at RS Ar Rasyid Palembang Indonesia in choosing growth factor therapy modalities from platelets for OA.