bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long term experimental verification of a single chip quantum random number generator fabricated on the InP platform
Authors: Chrysostomidis Themistoklis , Roumpos Ioannis , Alvarez Outerelo David , Troncoso-Costas Marcos , Moskalenko Valentina , Garcia-Escartin Juan Carlos , Diaz-Otero Francisco J. , Vyrsokinos Konstantinos 
Published: February 2023

AbstractThis work presents the results from the experimental evaluation of a quantum random number generator circuit over a period of 300 minutes based on a single chip fabricated on the InP platform. The circuit layout contains a gain switched laser diode (LD), followed by a balanced Mach Zehnder Interferometer for proper light power distribution to the two arms of an unbalanced MZI incorporating a 65.4 mm long spiral waveguide that translates the random phase fluctuations to power variations. The LD was gain-switched at 1.3 GHz and the chip delivered a min-entropy of 0.5875 per bit after removal of the classical noise, resulting a total aggregate bit rate of 6.11 Gbps. The recoded data set successfully passed the 15-battery test NIST statistical test suite for all data sets.
A Trans-Season Out-of-Phase Relationship of Tropical Cyclogenesis between the Western North Pacific and South China Sea
Authors: Cao Xi , Wu Renguang , Xu Liangtao , Wang Zhibiao , Sun Ying , Dai Yifeng , Chen Sheng 
Published: February 2023

Abstract
The present study investigates the relationship of tropical cyclone (TC) genesis between the western North Pacific (WNP) and South China Sea (SCS) from 1979 to 2020. A significantly out-of-phase variation is found between spring [March–May (MAM)] TC genesis over the WNP and the following summer–fall [June–November (JJASON)] TC genesis over the SCS. More TCs over the WNP in MAM are followed by fewer TCs over the SCS in the succeeding JJASON. Composite analysis and numerical model experiments show that negative sea surface temperature (SST) anomalies during MAM in the tropical central-eastern Pacific (CEP) and southeastern Indian Ocean work together to induce a lower-level cyclonic circulation over the WNP, with the latter more important. The positive specific humidity and ascending motion favor the TC genesis over the WNP in MAM. In the following JJASON, the SST anomalies are reversed in the tropical CEP. The positive precipitation anomalies over the western-central Pacific induced by positive SST anomalies further stimulate an anomalous zonal overturning circulation with anomalous descending motion and boundary layer divergence over the SCS. In addition, the persistent negative SST anomalies around the Maritime Continent (MC) induce an anomalous anticyclone to the west. Both processes lead to negative genesis potential index (GPI) anomalies and thus inhibit the TC genesis over the SCS. This out-of-phase relationship of TC genesis between the WNP and SCS also exists when the El Niño–Southern Oscillation (ENSO) transition years are removed. This finding may be helpful to improve the seasonal prediction of the SCS TC activity over the peak TC season.
Land and Atmosphere Conditions prior to Extreme Great Plains Low-Level Jets
Authors: Matus Sean A. , Dominguez Francina , Ford Trent W. 
Published: February 2023

Abstract
The warm season in the United States Great Plains (GP) is characterized by frequent nocturnal low-level jets (LLJs). The GPLLJ serves as a major mechanism of atmospheric moisture transport, contributing to severe weather and precipitation in the region. A combination of synoptic and regional forcing modulates GPLLJ frequency and intensity. The GPLLJ has primarily been studied at the diurnal scale. We hypothesize that, due to the memory of the land surface, longer time scale variability associated with surface moisture also modulates GPLLJ intensity. This work identifies GPLLJ days from ECMWF Reanalysis v5 (ERA5) wind data and isolates extremes using a peaks-over-threshold approach. Extreme GPLLJs are classified by geographic region and synoptic state. Composites of daily soil moisture anomalies show a preference for extreme GPLLJs to occur over anomalously dry soil. Critically, antecedent soil moisture anomalies emerge weeks before the extreme jet occurrence. The dry soil moisture signal coexists with clear skies and drying of the surface at the synoptic time scale. A diurnal PBL heat accumulation, which intensifies the buoyancy oscillation, is also present. The identification of a subseasonal dry anomaly suggests that, although the GPLLJ is generated by diurnally varying oscillations and intensified by synoptic-scale processes, the memory of the land surface can modulate the GPLLJ far beyond the diurnal and synoptic scale. Additionally, the location of the antecedent soil moisture anomalies corresponds with the eventual GPLLJ. The spatiotemporal characteristic of these antecedent anomalies suggests the potential for improved prediction of the GPLLJ activity.
Wages, Price, and Profit: Protection and Value Capture in the Mercosur Automotive Industry
Authors: Fitzsimons Alejandro , Guevara Sebastián 
Published: February 2023

The expansion of the automotive industry in Argentina and Brazil and its regional integration can be attributed to determinants that differentiate them from other contemporary regionalization processes. Their limited scales of production, outmoded technology, and lower productivity levels than the average in the world market and the inward orientation of regional industry are shared characteristics of the two national processes of capital accumulation, which are still organized around the appropriation by industrial capital of a portion of the substantial ground rent available. La expansión de la industria automotriz en Argentina y Brasil, así como su integración regional, pueden atribuirse a determinantes que las diferencian de otros procesos de regionalización contemporáneos. Sus limitadas escalas de producción, la tecnología anticuada y niveles de productividad más bajos que el promedio en el mercado mundial, así como la orientación interna de la industria regional, son características compartidas por ambos procesos nacionales de acumulación de capital, los cuáles todavía se encuentran organizados en torno a la apropiación, por parte del capital industrial, de una parte de la renta sustancial disponible.
Young Tzeltal Migrants from the Ejido to California’s Cities
Authors: Cruz-Salazar Tania 
Published: February 2023

The meaning of “youth” is changing among young Tzeltal migrants from Chiapas, Mexico, living in the U.S. state of California. Migration improves young people’s condition in terms of work, leisure time, and cultural consumption. A study based on ethnographic data, interviews, questionnaires, and participant observation undertaken in 2011, 2013, and 2016 shows how the material resources to which these migrants have access are directed toward building a unique youth style based on aesthetics and language that can be called the “Tzeltal jungle cowboy.” El significado del concepto “juventud” está cambiando entre los jóvenes migrantes tzeltales de Chiapas, México, que viven en el estado de California en Estados Unidos. La migración mejora las condiciones de vida de los jóvenes debido a su acceso al trabajo, tiempo libre y consumo cultural. Un estudio hecho en base a datos etnográficos, entrevistas, cuestionarios y observación participante realizado en 2011, 2013 y 2016 nos muestra cómo los recursos materiales a los que tienen acceso estos migrantes se dirigen a construir un estilo juvenil único basado en la estética y el lenguaje que podría denominarse el “vaquero tzeltal de la selva”.
Territorial Dispossession in Mexico: Mining and the New Latifundism
Authors: Tassinari Aideé 
Published: February 2023

Three multibillionaire-owned consortia in Mexico—Carlos Slim Helu’s Minera Frisco, Germán Larrea’s Grupo México, and Alberto Baillères’s Industrias Peñoles—have played a leading role in the process of accumulation through dispossession by perpetrating violence against indigenous and peasant communities in the form of the expulsion of thousands of people from their land, attacks on their security, health and ways of life, environmental depredation, fraud, criminalization, and murder. Examination of media reports of the most recent socio-environmental conflicts and corporate documents reveals the tension between profit accumulation through dispossession and territorial depredation in mining and various forms of resistance. Los consorcios multimillonarios mexicanos—Minera Frisco de Carlos Slim Helu, Grupo México de Germán Larrea e Industrias Peñoles de Alberto Baillères—han desempeñado un papel protagónico en el proceso de acumulación a través del despojo efectuado a través de la perpetración de actos de violencia contra las comunidades indígenas y campesinas. Esto se ha manifestado en la expulsión de miles de personas de sus tierras, ataques a su seguridad, salud y formas de vida, así como depredación ambiental, fraude, criminalización y asesinato. Un análisis de los informes hechos por los medios de comunicación en torno a los conflictos socioambientales más recientes así como de documentos corporativos revela la tensión existente entre la acumulación de ganancias a través del despojo y la depredación territorial en el rubro de la minería, al igual que diversas formas de resistencia.
The impact of epigenetic mechanisms in migraine: Current knowledge and future directions
Authors: Gallardo Víctor José , Vila-Pueyo Marta , Pozo-Rosich Patricia 
Published: February 2023

Background Epigenetic mechanisms, including DNA methylation, microRNAs and histone modifications, may modulate the genetic expression in migraine and its interaction with internal and external factors, such as lifestyle and environmental changes. Objective To summarize, contextualize and critically analyze the published literature on the current state of epigenetic mechanisms in migraine in a narrative review. Findings The studies published to date have used different approaches and methodologies to determine the role of epigenetic mechanisms in migraine. Epigenetic changes seem to be involved in migraine and are increasing our knowledge of the disease. Conclusions Changes in DNA methylation, microRNA expression and histone modifications could be utilized as biomarkers that would be highly valuable for patient stratification, molecular diagnosis, and precision medicine in migraine.
Outcomes Among People With Schizophrenia Participating in General-Population Smoking Cessation Treatment: An Observational Study
Authors: Veldhuizen Scott , Behal Anjali , Zawertailo Laurie , Melamed Osnat , Agarwal Mahavir , Selby Peter 
Published: February 2023

Objective People with schizophrenia are much more likely than others to smoke tobacco, raising risks of disease and premature mortality. These individuals are also less likely to quit successfully after treatment, but the few existing clinical and observational studies have been limited by small sample sizes, and have generally considered specialized treatment approaches. In this analysis, we examine outcomes, service use, and potential explanatory variables in a large sample of people with schizophrenia treated in a general-population cessation program. Method Our sample comprised 3,011 people with schizophrenia and 77,790 controls receiving free nicotine replacement therapy through 400 clinics and health centres. We analysed self-reported 7-day abstinence or reduction at 6-month follow-up, as well as the number of visits attended and self-reported difficulties in quitting. We adjusted for demographic, socioeconomic, and health variables, and used multiple imputation to address missing data. Results Abstinence was achieved by 16.2% (95% confidence interval [CI], 14.5% to 17.8%) of people with schizophrenia and 26.4% (95% CI, 26.0% to 26.7%) of others (absolute difference = 10.2%; 95% CI, 8.5% to 11.9%; P < 0.001). After adjustment, this difference was reduced to 7.3% (95% CI, 5.4% to 9.3%; P < 0.001). Reduction in use was reported by 11.8% (95% CI, 10.3% to 13.3%) and 12.5% (95% CI, 12.2% to 12.8%), respectively; this difference was nonsignificant after adjustment. People with schizophrenia attended more clinic visits (incidence rate ratio [IRR] = 1.15, 95% CI = 1.12% to 1.18%, P < 0.001) and reported more difficulties related to “being around other smokers” (odds ratio [OR] = 1.28; 95% CI, 1.11% to 1.47%; P = 0.001). Conclusion There is abundant demand for tobacco cessation treatment in this population. Outcomes were substantially poorer for people with schizophrenia, and this difference was not explained by covariates. Cessation remained much better than for unaided quit attempts, however, and engagement was high, demonstrating that people with schizophrenia benefit from nonspecialized pharmacological treatment programs.
Outcomes of Keller Gap Arthroplasty for Plantar Hallux Interphalangeal Joint Ulcers in Patients With Diabetes Mellitus
Authors: Periasamy Madhu , Muthukumar Vamseedharan , Mali Reddy Radhika , Asokan Kumanan , Sabapathy S. Raja 
Published: February 2023

Background: Hallux ulcers are known for their recurrence and associated risk for future amputations. Traditional nonsurgical external offloading methods have poor compliance rates, and the data is sparse on surgical offloading of hallux ulcers. We performed this study to analyze the outcomes of Keller excision gap arthroplasty of the first metatarsophalangeal joint in patients with a neuropathic plantar hallux interphalangeal joint (IPJ) ulcer in patients with diabetes mellitus. Methods: A retrospective study of 105 diabetic patients with a plantar hallux IPJ ulcer who underwent a Keller excision gap arthroplasty between December 2014 and June 2020 was done. A total of 122 great toes had been operated upon for hallux IPJ ulcers. We studied the long-term wound healing rates from patient records and then did a prospective survey of the postreview period. Results: All the hallux IPJ ulcers healed well in the immediate postoperative period. Six patients reported a recurrence of the ulcer at the original site during a mean follow-up period of 30 months. For these 6 patients, the mean time to recurrence of ulcer after operation was 2.5 years. Conclusion: At an average of 30 months, we found the Keller gap arthroplasty for treatment of noninfected and nonischemic diabetic foot hallux IPJ ulcers was associated with an ulcer recurrence rate of 5%. Level of Evidence: Level IV, cohort study.
Outbreak management of multidrug-resistant Bordetella bronchiseptica in 16 shelter-housed cats
Authors: Rodriguez Lisa , Berliner Elizabeth A 
Published: February 2023

Case series summary This case series describes an outbreak of multidrug-resistant (MDR) Bordetella bronchiseptica in 16 shelter-housed cats with infectious respiratory disease. Four cats presented with acute dyspnea on the same day, each with a history of previous upper respiratory disease that had resolved with treatment. Early diagnostic testing and culture and sensitivity allowed for targeted antimicrobial therapy and environmental interventions. A case definition based on exposure and clinical signs identified 12 additional presumptive cases, including the likely index case. Comprehensive outbreak management included diagnostic testing, risk assessment, vaccination, use of isolation and quarantine, increased surveillance and review of biosecurity practices. The outbreak resolved in 26 days. Relevance and novel information Management of an MDR B bronchiseptica outbreak in shelter-housed cats has not been previously described. Along with standard population and environmental measures, early and appropriate use of necropsy, PCR and bacterial culture allowed rapid and appropriate use of effective, second-line antibiotics. Shelters are resource-challenged population centers. Veterinarians working in animal shelters can play an important role in helping to develop cost-efficient and effective antimicrobial stewardship practices for companion animal settings. Outbreak management expertise and funding for diagnostic testing, as well as application of the principles of antimicrobial stewardship, are essential components of shelter medicine practice.
Clinical Characteristics and Outcomes of Diabetic Ketoacidosis in Patients With Type 2 Diabetes using SGLT2 Inhibitors
Authors: Almazrouei Raya , Afandi Bachar , AlKindi Fatima , Govender Romona , Al-Shamsi Saif 
Published: February 2023

Background: Sodium glucose cotransporter 2 inhibitors (SGLT2i) use is associated with an increased risk of diabetic ketoacidosis (DKA). Objective: This study evaluated and compared the DKA characteristics and outcomes of users and non-users of SGLT2i. Methods: We retrospectively studied patients with type 2 diabetes mellitus (T2DM) admitted with DKA to Tawam Hospital, Al Ain City, UAE between January 2017 and March 2021. Demographic data, clinical, and laboratory findings were extracted from the electronic medical records. Results: A total of 55 patients with T2DM (62% UAE nationals, 50% women) were admitted with DKA. The average age was 54.0 ± 18.9 years and average diabetes duration of 15.7 ± 15.1 years. Seventeen patients (31%) were using SGLT2i. Infection was the main precipitating factor for DKA in (8 out of 17) SGLT2i users. Compared to non-users, SGLT2i users had lower systolic blood pressure (119.9 vs 140 mmHg; P = .012) and serum glucose levels (16.2 vs 24.9 mmol/L; P < .001) and higher Na level (137.5 vs 132.6 mmol/L; P = .005). Additionally, 56.3% of SGLT2i users had euglycemic DKA compared to 2.6% of nonusers ( P < .001). Acute kidney injury (AKI) occurred more in SGLT2i users compared to non-users (94.1% vs 67.6%, P = .043). Further analysis revealed that SGLT2i users were about five times more likely to have prolonged hospital length of stay (⩾14 days) when compared with non-users (adjusted OR: 4.84; P = .035). Overall, there was no difference between the two groups with regards to DKA complications and mortality. Conclusions: SGLT2i related DKA is associated with lower blood glucose levels, lower SBP, worse hypovolemia, increased risk of AKI, and longer hospital stay when compared to non SGLT2i related episodes. Since the benefits of SGLT2 inhibitors far outweigh potential risks, there is a need to raise healthcare professionals and patients’ awareness about this potential association.
Scoping review: Evidence for long-term follow-up and monitoring in shoulder and elbow arthroplasty
Authors: Morris Daniel Leslie James , Candal-Couto Jaime , Watts Adam Charles , Rangan Amar , Tambe Amol 
Published: February 2023

Aims Long-term follow-up and monitoring of asymptomatic shoulder and elbow arthroplasty remains contentious, with a wide spectrum of non-evidence-based mechanisms used. This scoping review aims to outline related evidence, thereby informing research requirements. Methods Studies relevant to shoulder and elbow arthroplasty follow-up, surveillance and time-related failure were included. The review included randomised controlled trials, systematic reviews and economic studies indexed in MEDLINE, Embase, Cochrane CDSR and Cochrane CENTRAL since 1 January 2012. In addition, all registry studies, follow-up studies, cohort studies and case reports indexed in MEDLINE since 1 January 2020 were included. The screening was undertaken by two reviewers. Key characteristics of each study were described, alongside a narrative review. Results Twenty-one articles were included. We were unable to identify evidence that long-term follow-up and monitoring of asymptomatic shoulder and elbow arthroplasty identifies failure or leads to a revision that is of reduced patient morbidity and cost. In addition, no evidence was apparent to inform whether patients will self-present with a failing implant. Several surveillance mechanisms were identified. Conclusion This scoping review highlights the paucity of evidence related to long-term follow-up and monitoring of shoulder and elbow arthroplasty, and the need for high-quality data to inform the development of evidence-based care pathways.
Improving the reliability of smartphone-based urine colorimetry using a colour card calibration method
Authors: Noor Azhar Muhaimin , Bustam Aida , Naseem Fathmath Sausan , Shuin Soo Siew , Md Yusuf Mohd Hafyzuddin , Hishamudin Naseeha Ubaidi , Poh Khadijah 
Published: February 2023

Objective Urine colorimetry using a digital image–based colorimetry is potentially an accessible hydration assessment method. This study evaluated the agreement between urine colorimetry values measured with different smartphone brands under various lighting conditions in patients with dengue fever. Methods The urine samples were photographed in a customized photo box, under five simulated lighting conditions, using five smartphones. These images were analyzed using Adobe Photoshop to obtain urine Red, Green and Blue (RGB) values with and without colour correction. A commercially available colour calibration card was used for colour correction. Using intraclass correlation coefficient (ICC), inter-phone and intra-phone agreements of urine RGB values were analyzed. Results Without colour correction, the various smartphones produced the highest agreement for Blue and Green values under the ‘daylight’ lighting condition. With colour correction, ICC values showed ‘exceptional’ inter-phone and intra-phone agreement for the Blue and Green values (ICC > 0.9). Red values showed ‘poor’ (ICC < 0.5) agreement with and without colour correction in all lighting conditions. Out of the five phones compared in this study, Phone 4 produced the lowest intra-phone agreement. Conclusions Colour calibration using photo colour cards improved the reliability of smartphone-based urine colorimetry, making this a promising point-of-care hydration assessment tool using the ubiquitous smartphone.