bluuebunny/crossref_metadata_2025_split huggingface dataset:
Subgenual and Hippocampal Pathways in Amygdala Are Set to Balance Affect and Context Processing
Authors: Joyce Mary Kate P. , Wang Jingyi , Barbas Helen 
Published: March 2023

The amygdala, hippocampus, and subgenual cortex area 25 (A25) are engaged in complex cognitive-emotional processes. Yet pathway interactions from hippocampus and A25 with postsynaptic sites in amygdala remain largely unknown. In rhesus monkeys of both sexes, we studied with neural tracers how pathways from A25 and hippocampus interface with excitatory and inhibitory microcircuits in amygdala at multiple scales. We found that both hippocampus and A25 innervate distinct as well as overlapping sites of the basolateral (BL) amygdalar nucleus. Unique hippocampal pathways heavily innervated the intrinsic paralaminar basolateral nucleus, which is associated with plasticity. In contrast, orbital A25 preferentially innervated another intrinsic network, the intercalated masses, an inhibitory reticulum that gates amygdalar autonomic output and inhibits fear-related behaviors. Finally, using high-resolution confocal and electron microscopy (EM), we found that among inhibitory postsynaptic targets in BL, both hippocampal and A25 pathways preferentially formed synapses with calretinin (CR) neurons, which are known for disinhibition and may enhance excitatory drive in the amygdala. Among other inhibitory postsynaptic sites, A25 pathways innervated the powerful parvalbumin (PV) neurons which may flexibly regulate the gain of neuronal assemblies in the BL that affect the internal state. In contrast, hippocampal pathways innervated calbindin (CB) inhibitory neurons, which modulate specific excitatory inputs for processing context and learning correct associations. Common and unique patterns of innervation in amygdala by hippocampus and A25 have implications for how complex cognitive and emotional processes may be selectively disrupted in psychiatric disorders.SIGNIFICANCE STATEMENTThe hippocampus, subgenual A25, and amygdala are associated with learning, memory, and emotions. We found that A25 is poised to affect diverse amygdalar processes, from emotional expression to fear learning by innervating the basal complex and the intrinsic intercalated masses. Hippocampal pathways uniquely interacted with another intrinsic amygdalar nucleus which is associated with plasticity, suggesting flexible processing of signals in context for learning. In the basolateral (BL) amygdala, which has a role in fear learning, both hippocampal and A25 interacted preferentially with disinhibitory neurons, suggesting a boost in excitation. The two pathways diverged in innervating other classes of inhibitory neurons, suggesting circuit specificities that could become perturbed in psychiatric diseases.
The Architecture of the Leisure Class: Thorstein Veblen and the University of Chicago
Authors: Merwood-Salisbury Joanna 
Published: March 2023

Abstract
The American economist Thorstein Veblen’s The Theory of the Leisure Class (1899) has been used to support and define concepts of architectural modernity for more than one hundred years. Best known for introducing the concept of “conspicuous consumption,” this influential book has been especially valuable for historians of the architecture of consumer culture. Yet curiously, Veblen’s own architectural examples have escaped scholarly attention. This article explores the link Veblen drew between Gothic Revival architecture and cultural barbarism. Inverting the concepts and terminology of race science, Veblen used the image of the Gothic Revival university to criticize the rhetoric of American exceptionalism. Seen through the lens of Veblen’s writing, Henry Ives Cobb’s design for the University of Chicago (1891–97), where Veblen taught for fourteen years, represents the transformation of leisure-class aesthetics under the logic of capitalism.
Effect of Sn doping on sinterability and electrical conductivity of strontium hafnate
Authors: Khaliullina Adelya S. , Meshcherskikh Anastasia N. , Dunyushkina Liliya A. 
Published: March 2023

The effect of isovalent substitution of hafnium by tin in strontium hafnate on sinterability and electrical conductivity was studied for the first time. The ceramic samples SrHfxSn1–xO3–δ (x = 0–0.16) were synthesized by solid-state reaction and sintered at 1600 °C for 5 h. The samples were examined using the methods of X-ray diffraction, scanning electron microscopy, impedance spectroscopy, and four-probe direct current technique. It was shown that all samples were phase pure and had the orthorhombic structure of SrHfO3 with the Pnma space group. Sn doping resulted in an increase in grain size, relative density and conductivity; the sample with x = 0.08 demonstrated the highest conductivity, which was ~830 times greater than that of undoped strontium hafnate at 600 °C. The conductivity of SrHf0.92Sn0.08O3–δ was 4.1∙10–6 S cm–1 at 800 °C in dry air. The possible reasons for the effect of Sn on the electrical properties of strontium hafnate were discussed.
USOS DAS TECNOLOGIAS DA INFORMAÇÃO E COMUNICAÇÃO NO ENSINO SUPERIOR DURANTE A PANDEMIA DA COVID-19
Authors: Oliveira Janaina Prieto , Esteves Thais Vieira , Silva Fernanda França Velo , Toledo Maria Elena Roman de Oliveira , Azevedo Sergio Alves , Morais Suelen Cristian de Freita 
Published: March 2023

A pandemia provocada pelo novo coronavírus trouxe uma série de desafios ao ensino superior e à educação como um todo. Resultou em fechamento das atividades nacionalmente, interrompendo o formato tradicional de ensino presencial e forçando professores e alunos a ficarem em casa. Com isso, as instituições de ensino foram compelidas a pensar em formas alternativas para continuidade do processo de ensino-aprendizagem. Assim, o campo educacional experimentou uma variação significativa com a inclusão das Tecnologias de informação e comunicação (TICs). Baseando-se no método qualitativo e exploratório, a pesquisa parte de um universo composto por 283 matérias jornalísticas online pertencentes aos dois primeiros anos de pandemia que, após seleção, resultou em 27 matérias para análise detalhada. Os resultados da investigação convergem para três conjuntos de domínios principais: (1) aspectos estruturais, (2) relativos ao corpo docente e ao (3) corpo discente. A análise pormenorizada dos materiais selecionados permitiu a constatação de que as TICs, enquanto ferramentas de suporte deram mais flexibilidade, adaptabilidade e dinamismo ao sistema educativo, permitindo a continuidade do processo de ensino. Embora o uso dessas tecnologias tenha trazido novas e significativas possibilidades para as práticas educativas, sua adoção enfrentou, e ainda enfrentam diversos desafios relacionados à formação docente, à resistência as mudanças por parte das equipes educativas, às características estruturais das instituições de ensino e à necessidade de motivação dos discentes.
Complications of percutaneous endoscopic gastrostomy in children: a single-center experience
Authors: ÖZÇELİK Zerrin , BANLI CESUR İlknur , GÜLCÜ TAŞKIN Didem 
Published: March 2023

Purpose: Percutaneous endoscopic gastrostomy is the most preferred method for feeding in children with intact gastrointestinal system functions when oral nutrition is insufficient due to neurological, neuromuscular, or oncological diseases. This study aimed to evaluate the indications for percutaneous endoscopic gastrostomy and associated complications in the patients we followed up.
Materials and Methods: In this descriptive study, the records of 130 patients who underwent percutaneous endoscopic gastrostomy for nutritional support between January 1st 2013- December 30th 2020 were retrospectively reviewed. Demographic data, indications, complications, and follow-up periods of the patients were examined.
Results: Of the patients, 75 were male and 55 were female. The mean age of the patients was 48 months (min 1 month-max 211 months). The evaluation of the patients with percutaneous endoscopic gastrostomy in terms of diagnosis revealed that 95 patients required nutritional support due to neuromotor retardation associated with neurological disease, 19 patients due to central nervous system tumor, and 13 patients due to metabolic disease. Considering complications, the most frequent minor complication was leakage in 11of the 33 patients, while the most frequent major complication was colonic fistulation in 6 of the 9 patients. Two patients required open surgery in the early period due to intra abdominal leak.
Conclusion: Although enteral nutrition with a percutaneous endoscopic gastrostomy tube seems to be an appropriate and reliable method to meet the nutritional needs of pediatric patients who have normal digestive system functions but cannot be fed orally due to swallowing disorders, it is necessary to pay attention to its complications like any surgical procedure.
Implementation of methods and times to increase productivity in a textile company
Authors: De Leon-Galeano Guiliana , Mendoza-Catañeda María Camila , Peña-Valdez Daniris , Hernández-Padilla Edita Marcela , Altamar-Cano José , Martínez-Olaya Jesús 
Published: March 2023

The realization of the research project was carried out in the textile company KEYSHAR'AR SPORT in order to implement the study of methods and times to increase the productivity of this, the objectives set were to identify the problems in the realization of the dresses, implement tools of analysis of study of the work and increase the productivity of the company, this through analytical diagrams, travel, and the respective productivity calculations. In the methodological phase of the project, a description of the garment company KEYSHAR'AR SPORTS was initially made, a process was chosen and what was observed in the current material used in the company was explained step by step, it was observed that the production process begins with the storage of the raw material then goes to the design area where a process of specific patterns is made to the fabrics used in each design is then taken to a cutting machine, from there it is transported to the garment machines; then the dress goes to the inspection area where it is verified if the product has imperfections, then those that pass the inspection are transported to the ironing area and then they are labeled and packed, in this way having made each of the diagrams of the methods, both the initial and the proposed, we proceed to find the percentage of processes, initially 12 processes that are reduced to 9, in addition some improvements are formulated to increase the performance and productivity of the company.
Distraction: A game changer-A comparative interventional study in children aged between 4-7 years
Authors: Kakkar Tanya , Srivastava Pooja , Saraf Bhavna Gupta , Sheoran Neha , Khan Anam Khushboo , Lakhanpal Pallavi 
Published: March 2023

Nowadays, various novel techniques have been documented to modify behaviour of the child and reduce dental anxiety in paediatric patients. Recently developed distraction methods have advancements that involve intellectual distraction games. This approach enables the clinicians to treat children with minimal resources and is readily accessible in the market. Several studies have also evaluated the productiveness of virtual reality (VR) as an audio-visual distraction aid in guiding anxious children.The aim of the present study was to compare and evaluate the effectiveness of virtual reality eyeglasses vs intellectual colored game as a distraction aid to reduce anxiety of children undergoing dental procedure.This was an in vivo interventional comparative study. A total sample of 90 children was selected aged between 4-7 years. They were randomly divided by chit method into three different groups with 30 children in each group: Group I (Control), Group II (VR) and Group III (ICG). Child’s anxiety level was assessed using a combination of physiological parameter (pulse rate and oxygen saturation) and behavioral measures including subjective assessment (Venham’s anxiety rating scale) and objective assessmemt (Facial Image Scale). Data was analysed using Statistical Package for Social Sciences (SPSS) version 21, IBM Inc.The study displayed a high statistically significant reduction in anxiety with VR & ICG Group when compared to Control group (p&#60;0.001)Mental distraction (Intellectual coloured game) was proven to be a more promising distraction aid due to certain limitations of Virtual reality distraction.
Dentoalveolar compensation in various skeletal malocclusion groups in district solan population: A cephalometric study
Authors: Manchanda Yenika , Goyal Merry , Mittal Sanjay , Aggarwal Isha , Avasthi Avijit 
Published: March 2023

: To assess the position and inclination of upper and lower incisors and bases in different groups of skeletal malocclusions. 45 pretreatment lateral cephalometric radiographs were included. They were divided into his three groups of skeletal class I, class II, and class III. A variety of linear and angular measurements were used to assess both the position and inclination of the maxillary and mandibular bases, incisors, and the relationship between the incisors. There was a significantly stronger correlation between anterior-posterior skeletal mismatch and maxillary alveolar bone compensation in skeletal classes I, II, and III. Except for maxillary vertical skeletal discrepancy (MP-SN) and alveolar compensation, there was a weak correlation between maxillary and mandibular vertical skeletal discrepancy and alveolar compensation. The anterior-posterior position of the skeletal jaw had a greater effect on alveolar bone changes than the vertical inclination of the skeletal jaw in the Grad variant. There may be a relationship between alveolar bone changes and skeletal anteroposterior and vertical position, inclination and intermaxillary relationship.
Inhibition of MDM2 Using Idasanutlin (RG-7388) enhances the Chemo-sensitivity of B-ALL Cells to Daunorubicin
Authors: Boustani Hassan , Abbasi Nasser , Ghotaslou Abbas , Ghalesardi Omid Kiani , Zaker Farhad , Shahidi Minoo 
Published: March 2023

Background: Although significant advances have been made in the treatment of cancer, a significant number of patients with acute lymphoblastic leukemia (ALL) show resistance to treatment. Thus, it is necessary to seek novel therapeutic agents to overcome this problem. Studies have indicated that the expression level of mouse double minute 2 (MDM2), a negative regulator of p53, is markedly elevated in patients with refractory or recurrent ALL. Thus, targeting MDM2 using a specific inhibitor, Idasanutlin, can increase the activity of p53. This study evaluated the possible synergistic effect of Idasanutlin and Daunorubicin on the induction of apoptosis in NALM-6 cells.
Materials and methods: In this fundamental study, the anti-proliferative effects of Idasanutlin on NALM-6 cells, either alone or in combination with Daunorubicin, were confirmed by MTT(methyl-thiazol-tetrazolium) assay, Annexin/PI apoptosis assay, and cell cycle analysis. Quantitative reverse transcription-PCR (qRT-PCR) and Western blot analyses were applied to elucidate the molecular mechanisms underlying the anti-leukemic activity of Idasanutlin.
Results: Idasanutlin synergistically enhanced Daunorubicin-induced apoptosis and activated caspase-3, thereby activating programmed cell death in a dose-dependent manner (P<0.001). The treatment of NALM-6 cells with Idasanutlin caused cell cycle arrest in the G1 phase by an increase in the expression of p21 (P<0.001). Moreover, a significant increase was detected in the expression of pro-apoptotic genes (P<0.001), as well as a remarkable decrease in the expression of anti-apoptotic (P<0.01) and multidrug resistance1 (MDR1) genes (P<0.01).
Conclusions: It seems that Idasanutlin can cooperatively promote daunorubicin-induced apoptosis in NALM-6 cells. These findings open up a new horizon in the application of Idasanutlin in combination with Daunorubicin to overcome drug resistance in patients with ALL.
Comunicação/educação: apontamentos para discussão
Authors: Baccega Maria Aparecida 
Published: March 2023

O texto aborda o campo da comunicação/educação como resultado do campo da comunicação, lugar de disputa entre as agências de formação do cidadão. Ressalta as mediações dos meios de comunicação, os quais selecionam, editam e interpretam os fatos do cotidiano, dando um determinado sentido às coisas do mundo. Adverte para o fato de que vivemos todos num mundo editado e que é a partir da crítica a ele que construímos a cidadania, o que torna indispensável distinguir informação de conhecimento e dar destaque à questão da recepção enquanto práticas culturais. Lembra o papel da publicidade, lugar privilegiado do encontro entre o já visto e o por ver. A reflexão sobre a pluralidade de sentidos passa pela escola que, se ressignificada, pode ser o espaço da transformação da informação fragmentada em conhecimento, o que implica reelaboração e capacidade de seleção.

Abstract:
The text approaches the communication/education field as a result of the communication field, a place of dispute between the agencies that form the citizen. It highlights the mediation of means of communication that select, edit and interpret the everyday facts, giving a certain sense to the worldly thing. Adverts to the act that we all live in an edited world and that it is from the criticism of it that we build the citizenship, what akes it indispensable to distinguish information from knowledge and to highlight the issue of reception as ultural practice. It reminds the role of publicity, privileged meeting place between the already seen and hat is yet to be seen. The reflection about the plurality of the senses passes by the school that, if re-signified, an be the space of transformation of fragmented information in knowledge, which implies re-elaboration and selection capacity.

Palavras-chave: comunicação; educação; recepção; campo comunicação/ educação.

Key-words: communication; education; reception; communication/education field.
Cultura, consumo e segmentação de público em anúncios de cosméticos
Authors: Palacios Annamaria da Rocha Jatobá 
Published: March 2023

RESUMO
O artigo analisa transformações em hábitos de consumo feminino, por meio da recente segmentação do produto cosmético. O fenômeno classificatório e diferenciador do cosmético bem como a conseqüente alteração do perfil identitário do público consumidor devem-se a alguns fatores: instauração de novos marcos biológicos que norteiam o princípio dos cuidados com o corpo; tentativa da publicidade de incluir o cosmético no rol das mercadorias de primeira necessidade; crescente democratização dos cuidados estéticos com o corpo; interesse econômico e produção industrial de mercadorias para vários nichos do mercado consumidor.
Palavras-chave: Publicidade; consumo; cultura contemporânea.
ABSTRACT
The article analyses changes in feminine consumer habits through an examination of recent market segmentation of cosmetic goods. Segmentation – and therefore the classification and differentiation of cosmetics lines – and its effects on identity profiles of consumers is examined. The article identifies and discusses some factors contributing to classification and differentiation, such as: the emergence of new biological guidelines related to body care; the attempt by the advertising industry to include cosmetics in the list of essential goods; the gradual democratization of aesthetic body care; the action of economic and industrial interests in mar-ket segmentation.
Keywords: Advertising; consumption; contemporary culture.
Bunker glocal: configuração majoritária sutil do imaginário mediático contemporâneo e militarização imperceptível da vida cotidiana
Authors: Trivinho Eugênio 
Published: March 2023

Bunker glocal – esta expressão heterodoxa – é o fundamento mediático do processo civilizatório contemporâneo. Sua análise no âmbito da teoria social e da comunicação apreende o principal aspecto de sua múltipla significação social-histórica: a militarização velada da existência humana
no contexto civil da era digital. Ao materializar essa injunção teórica, o presente artigo detalha os vínculos inextricáveis entre processo de bunkerização ampliada, imaginário social e fenômeno glocal (além do global e do local), para, em conclusão, qualificar o bunker glocal como linguagem matricial de equivalência generalizada na cibercultura.
Palavras-chave: Comunicação; cibercultura; bunker glocal; processo de
bunkerização; militarização velada da vida social.
ABSTRACT
Glocal bunker – this heterodox expression – is the mediatic fundament of the contemporary civilizing process. Its analysis within the ambit of social and communication theory apprehends the principal aspects of its multiple social and historical meaning: the covert militarization of human existence in the civil context of the digital era. By materializing this theoretical injunction, this article details the inextricable links between the expanded bunkering process, the social imaginary and the glocal phenomenon (beyond the global and local), and concludes by qualifying the glocal bunker as a matricial language of generalized equivalence in cyberculture.
Keywords: Communication; cyberculture; glocal bunker; bunkering process;
covert militarization of social life.
El consumo juvenil en la sociedad mediática
Authors: González Germán Muñoz 
Published: March 2023

Los modos de vida de los jóvenes están cada día más afectados en el mundo globalizado por formas de comunicación mediadas por internet. El artículo analiza algunos efectos, retos y perspectivas, en particular aquellos que tienen relación con sus producciones de sentido y sus identidades en formación. Se exploran asuntos tales como las reconfiguraciones de sus espacios culturales; el paradójico aislamiento en el ciberespacio; los usos innovadores de las TICs (Tecnologías de la Información y la Comunicación), la producción de saberes y nuevas identidades.
Palabras clave: Consumo; jóvenes; medios de comunicación.
Abstract
Young people are increasingly linked around the globe by a common mass media and forms of internet communication. This article examines the effects, challenges, and promises these recent developments have on young people’s sense of identity. Questions explored are: how an increase in a common cultural space affects young people’s sense of space and future prospects; how youth in isolated communities enhance their sense of themselves in the world through cyberspace activities; how these technologies are being used; and how mediated knowledge produce new forms of identity.
Keywords: Youth; consumption; mass media.
Estratégias de personalização e sites de redes sociais: um estudo de caso da apropriação do Fotolog.com
Authors: Recuero Raquel 
Published: March 2023

O presente trabalho busca estudar as estratégias de personalização dos usuários do Fotolog.com. Essas estratégias são compreendidas como essenciais para o uso do sistema como um site de rede social. A análise e a identificação de tais estratégias são realizadas com base em um estudo de caso de 20 fotologs. São diretamente observados 242 fotografias e 1583 comentários. Baseadas nessa observação sistemática e na análise do conteúdo, são elencadas quatro formas de personalização: pelas fotografias
publicadas, pelo nickname utilizado; pelas conexões e pelas configurações do sistema. Essas estratégias são depois discutidas diante de sua importância para a interação social e para as redes sociais.
Palavras-chave: Fotolog; personalização; sites de redes sociais.
ABSTRACT
The following paper studies the users’ personalization strategies on Fotolog. com. These strategies are essential for Fotolog’s appropriation as a social network site. We identify which strategies are used and how based on a case study of 20 fotologs, in which we observed directly 242 photographies
and 1583 comments. Based on this systematic observation andcontent analysis, we point out four strategies of personalization: through photographies published, nicknames used, connections and system configuration. We then discuss these strategies and their importance for social interaction and social networks.
Keywords: Fotolog; personalization; social network sites.