bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical index to quantify the 1-year risk for common postpartum mental disorders at the time of delivery (PMH CAREPLAN): development and internal validation
Authors: Vigod Simone N. , Urbach Natalie , Calzavara Andrew , Dennis Cindy-Lee , Gruneir Andrea , Thombs Brett D. , Walker Mark , Brown Hilary K. 
Published: June 2023

BackgroundCommon postpartum mental health (PMH) disorders such as depression and anxiety are preventable, but determining individual-level risk is difficult.AimsTo create and internally validate a clinical risk index for common PMH disorders.MethodUsing population-based health administrative data in Ontario, Canada, comprising sociodemographic, clinical and health service variables easily collectible from hospital birth records, we developed and internally validated a predictive model for common PMH disorders and converted the final model into a risk index. We developed the model in 75% of the cohort (n = 152 362), validating it in the remaining 25% (n = 75 772).ResultsThe 1-year prevalence of common PMH disorders was 6.0%. Independently associated variables (forming the mnemonic PMH CAREPLAN) that made up the risk index were: (P) prenatal care provider; (M) mental health diagnosis history and medications during pregnancy; (H) psychiatric hospital admissions or emergency department visits; (C) conception type and complications; (A) apprehension of newborn by child services (newborn taken into care); (R) region of maternal origin; (E) extremes of gestational age at birth; (P) primary maternal language; (L) lactation intention; (A) maternal age; (N) number of prenatal visits. In the index (scored 0–39), 1-year common PMH disorder risk ranged from 1.5 to 40.5%. Discrimination (C-statistic) was 0.69 in development and validation samples; the 95% confidence interval of expected risk encompassed observed risk for all scores in development and validation samples, indicating adequate risk index calibration.ConclusionsIndividual-level risk of developing a common postpartum mental health disorder can be estimated with data feasibly collectable from birth records. Next steps are external validation and evaluation of various cut-off scores for their utility in guiding postpartum individuals to interventions that reduce their risk of illness.
Survival After Implementation of a Decision Support Tool to Facilitate Evidence-Based Cancer Treatment
Authors: Ojha Rohit P. , Lu Yan , Narra Kalyani , Meadows Rachel J. , Gehr Aaron W. , Mantilla Emmanuel , Ghabach Bassam 
Published: June 2023

PURPOSE Decision support tools (DSTs) to facilitate evidence-based cancer treatment are increasingly common in care delivery organizations. Implementation of these tools may improve process outcomes, but little is known about effects on patient outcomes such as survival. We aimed to evaluate the effect of implementing a DST for cancer treatment on overall survival (OS) among patients with breast, colorectal, and lung cancer. METHODS We used institutional cancer registry data to identify adults treated for first primary breast, colorectal, or lung cancer between December 2013 and December 2017. Our intervention of interest was implementation of a commercial DST for cancer treatment, and outcome of interest was OS. We emulated a single-arm trial with historical comparison and used a flexible parametric model to estimate standardized 3-year restricted mean survival time (RMST) difference and mortality risk ratio (RR) with 95% confidence limits (CLs). RESULTS Our study population comprised 1,059 patients with cancer (323 breast, 318 colorectal, and 418 lung). Depending on cancer type, median age was 55-60 years, 45%-67% were racial/ethnic minorities, and 49%-69% were uninsured. DST implementation had little effect on survival at 3 years. The largest effect was observed among patients with lung cancer (RMST difference, 1.7 months; 95% CL, –0.26 to 3.7; mortality RR, 0.95; 95% CL, 0.88 to 1.0). Adherence with tool-based treatment recommendations was >70% before and >90% across cancers. CONCLUSION Our results suggest that implementation of a DST for cancer treatment has nominal effect on OS, which may be partially attributable to high adherence with evidence-based treatment recommendations before tool implementation in our setting. Our results raise awareness that improved process outcomes may not translate to improved patient outcomes in some care delivery settings.
Obstetric and Gynecologic Disorders and the Nervous System
Authors: Marulanda Erika , Tornes Leticia 
Published: June 2023

ABSTRACTOBJECTIVEThis article discusses obstetric and gynecologic associations with common neurologic disorders.LATEST DEVELOPMENTSNeurologic complications of obstetric and gynecologic disorders can arise throughout the lifespan. Caution should be exercised when prescribing fingolimod and natalizumab to patients with multiple sclerosis who are of childbearing potential because of the risk of disease rebound when they are discontinued. OnabotulinumtoxinA is considered safe in pregnancy and lactation based on long-term observational data. Hypertensive disorders of pregnancy are associated with higher subsequent cerebrovascular risk, likely via multiple mechanisms.ESSENTIAL POINTSNeurologic disorders may present in a variety of obstetric and gynecologic contexts, with meaningful implications for recognition and treatment. These interactions must be considered when treating women with neurologic conditions.
Hematologic Disorders and the Nervous System
Authors: Mauermann Michelle L. , Southerland Andrew M. 
Published: June 2023

ABSTRACTOBJECTIVEThis article discusses the epidemiology, diagnosis, treatment, and prevention of neurologic complications of red blood cell, platelet, and plasma cell disorders.LATEST DEVELOPMENTSCerebrovascular complications can occur in patients with blood cell and platelet disorders. Treatment strategies to prevent stroke are available for patients with sickle cell disease, polycythemia vera, and essential thrombocythemia. A diagnosis of thrombotic thrombocytopenic purpura should be considered in patients with neurologic symptoms, hemolytic anemia, thrombocytopenia, mild renal insufficiency, and fever. Plasma cell disorders can be associated with peripheral neuropathy, and classification of the monoclonal protein type and neuropathy aid in diagnosis. Patients with POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder, and skin changes) syndrome can present with arterial and venous neurologic events.ESSENTIAL POINTSThis article discusses the neurologic complications of blood cell disorders and the most recent advances in prevention and treatment.
Viral evasion of the interferon response at a glance
Authors: Zhu Junji , Chiang Cindy , Gack Michaela U. 
Published: June 2023

ABSTRACT
Re-emerging and new viral pathogens have caused significant morbidity and mortality around the world, as evidenced by the recent monkeypox, Ebola and Zika virus outbreaks and the ongoing COVID-19 pandemic. Successful viral infection relies on tactical viral strategies to derail or antagonize host innate immune defenses, in particular the production of type I interferons (IFNs) by infected cells. Viruses can thwart intracellular sensing systems that elicit IFN gene expression (that is, RIG-I-like receptors and the cGAS–STING axis) or obstruct signaling elicited by IFNs. In this Cell Science at a Glance article and the accompanying poster, we review the current knowledge about the major mechanisms employed by viruses to inhibit the activity of intracellular pattern-recognition receptors and their downstream signaling cascades leading to IFN-based antiviral host defenses. Advancing our understanding of viral immune evasion might spur unprecedented opportunities to develop new antiviral compounds or vaccines to prevent viral infectious diseases.
Vicarious Learning Without Knowledge Differentials
Authors: Park Sanghyun , Puranam Phanish 
Published: June 2023

The benefits of vicarious learning are usually conceptualized in terms of a mechanism for learners to utilize the superior knowledge of others. Building on the fact that vicarious learning typically co-occurs and interacts with individual learning-by-doing, we propose an alternative mechanism—one in which vicarious learning is useful because it corrects for certain well-known limitations of individual learning-by-doing. Using computational agent-based models, we show that, under this mechanism, vicarious learning can be beneficial, even without any ex ante differential knowledge to exploit. Our analysis contributes to a deeper understanding of the microfoundations of vicarious learning, which is a vital component of organizational learning. We draw implications for empirical analysis and managerial practice. This paper was accepted by Lamar Pierce, organizations. Funding: Financial support from The Desmarais Fund at INSEAD is gratefully acknowledged. Supplemental Material: The data file and online appendix are available at https://doi.org/10.1287/mnsc.2023.4842 .
Are patients with HHV-8 associated Castleman disease successfully treated with rituximab at risk of subsequently developing HHV-8 negative (idiopathic) Castleman disease? iMCD after HHV-8-associated MCD
Authors: Ha Gavin , Kwong Kelsey , Tanaka Bryce , Nishimura Yoshito , Chong Christina 
Published: June 2023

Introduction: Multicentric Castleman disease (MCD) is a lymphoproliferative disorder characterized by lymph node histopathology and systemic symptoms. To our knowledge, there are no descriptions in the literature of long-term outcomes of human herpesvirus-8 (HHV-8)-associated MCD. Case Description: We report a case of a 70-year-old male living with human immunodeficiency virus and a history of human herpesvirus-8 (HHV-8)-associated MCD. The patient reported having had low-grade fever for two weeks. Extensive workup revealed systemic lymphadenopathy without evidence of autoimmune disease or malignancy. Lymph node biopsy was consistent with HHV-8-negative idiopathic MCD (iMCD). The patient was subsequently scheduled for anti-interleukin-6 therapy. Discussion: The present case is the first report of probable development of iMCD after long-term follow-up for HHV-8-associated MCD. The case illustrates the possible long-term consequences of MCD, suggesting the necessity of further research on the pathogenesis of CD. Conclusion: Given the uncertainty in the long-term outcomes of HHV-8-associated MCD, periodic surveillance of patients with a history of HHV-8-associated MCD is warranted. Prospective nationwide cohort studies comparing characteristics of HHV-8-associated MCD and iMCD would bring further insights.
Post-death burial and funeral practices in rural Alberta
Authors: Grainger Brooklyn , Wilson Donna M , Rainsford Suzanne 
Published: June 2023

Background: Burial and funeral practices are important customary mortuary rituals, especially in rural areas as people are likely to have different values and interests than people who live in larger cities. However, little is known about rural post-death practices in Canada. Aims: This review gathered information on funeral and burial practices in rural Alberta, a western Canadian province with a diverse rural population. Methods: A literature review of community print sources, including obituaries and funeral home websites, was conducted for select representative rural communities. Findings: This review found that cremations outnumber burials, and mortuary ceremonies more commonly occur in non-religious settings. Furthermore, personalised post-death rituals were identified as highly significant to rural people as they allow the dead to remain connected to their rural land, family and community. Conclusion: It is important to understand rural mortuary rituals to help prepare dying rural people and their families.
Paediatric end-of-life care at home
Authors: Larsen Signe Hoff Kobborg , Bording Inger , Bjergegaard Margit , Buchreitz Jakob , Mouritzen Bente Toth , Brix Lotte , Jespersen Bodil Abild , Neergaard Mette Asbjoern 
Published: June 2023

Background: A terminally ill child should have the possibility to be at home with their family during the end of life. Provision of care from primary care nurses (PCNs) is crucial, but no model exists on how specialised paediatric palliative care teams (SPPCTs) support the PCNs to perform this task. Aim: To investigate how PCNs evaluated a shared care model between a SPPCT and PCNs in paediatric end-of-life care. Method: A 23-item questionnaire was distributed to PCNs involved in care of 14 terminally ill children in November 2019 and January 2020. Descriptive statistics were used. Findings: A total of 20 questionnaires were returned from nurses who agreed/completely agreed that an introductory meeting made them better prepared (78.9%) to deal with the death of a child in their care, cooperating with family members (70.6%) and dealing with own emotions (73.7%). A total of 69.2% felt the meeting helped coping with parents' pressure and 88.9% stated that the trajectory changed how they saw themselves involved in future paediatric palliative care. Conclusion: The shared care model was evaluated positively. Clear agreements and specialist support were prerequisites for good trajectories at the end of life. Further research is needed to investigate if the shared care model optimises palliative care and security in relation to child and family.
HUBUNGAN KECERDASAN EMOSIONAL DAN ADAPTABILITAS KARIER PADA SISWA KELAS XII SMA SANTA URSULA JAKARTA
Authors: Paradita Cornelia Tasya , Sawitri Dian Ratna 
Published: June 2023

Adaptabilitas karier merupakan kesiapan dan kemampuan yang dimiliki oleh seorang individu dalam memilih, menentukan, menghadapi, serta mengatasi tantangan dalam masa depannya, baik yang dapat diduga ataupun tidak terduga. Kecerdasan emosional merupakan kemampuan individu untuk mengenali dan memahami diri sendiri serta orang lain sehingga dapat menyesuaikan diri dengan lingkungannya. Siswa SMA kelas XII sedang berada berada pada tahap perkembangan karier eksplorasi dan merupakan populasi yang akan menghadapi transisi dari jenjang pendidikan menuju karier dunia kerja, sehingga diharapkan mampu untuk beradaptasi, baik di lingkungan pendidikan yang lebih tinggi maupun di lingkungan kerja. Penelitian ini bertujuan untuk mengetahui hubungan antara kecerdasan emosional dan adaptabilitas karier pada siswa kelas XII SMA Santa Ursula Jakarta. Populasi dalam penelitian ini sejumlah 213 siswa kelas XII dengan sampel sebanyak 144 siswa, yang diambil dengan cluster random sampling. Alat ukur yang digunakan dalam penelitian ini yaitu Skala Kecerdasan Emosional (24 aitem, ) dan Skala Adaptabilitas Karier (23 aitem, ). Teknik analisis data menggunakan analisis Spearman’s Rank dan menunjukkan adanya hubungan positif yang signifikan antara kecerdasan emosional dan adaptabilitas karier (rxy = 0,354, p = 0,000). Artinya, semakin tinggi kecerdasan emosional, maka semakin tinggi adaptabilitas karier, dan sebaliknya semakin rendah kecerdasan emosional, maka semakin rendah pula adaptabilitas karier.
Pengaruh Kadar Timbal dalam Darah terhadap Peningkatan Kadar Superoxide Dismutase (SOD) pada Preeklampsia
Authors: Pramono Besari Adi , Faradz Sultana M.H , Suhartono Suhartono , Pramono Noor 
Published: June 2023

Latar Belakang: Angka kematian ibu (AKI) adalah masalah yang masih menjadi perhatian khusus di Indonesia. Preeklampsia adalah suatu komplikasi dalam kehamilan yang menjadi salah satu penyebab utama mortalitas ibu dan janin di seluruh dunia. Preeklampsia pun merupakan penyakit yang seringkali menyebabkan seorang ibu hamil memerlukan perawatan hingga di intensive care unit (ICU). Paparan timbal merupakan faktor risiko penting kejadian preeklampsia, dimana ibu hamil dengan preeklampsia memiliki kadar timbal darah lebih tinggi secara signifikan dari rata – rata kehamilan normal. Penurunan kadar Antioksidan juga secara konsisten berhubungan dengan kejadian preeklampsia. Dibutuhkan pengkajian lebih lanjut mengenai hubungan antara kadar timbal darah dengan status antioksidan pada pasien preeklampsia.Tujuan: Untuk mengetahui dan menganalisis kadar timbal sebagai faktor risiko terhadap peningkatan kadar superoxide dismutase (SOD).Metode: Penelitian ini merupakan penelitian observasi analitik dengan metode case control pada 46 ibu hamil dengan preeklampsia yang berobat di RSUD Kabupaten Brebes. Dilakukan pemeriksaan kadar timbal darah dengan metode SSA dan SOD serum dengan metode enzyme linked imunosorben assay (ELISA).Hasil: Rerata kada Pb darah dalam penelitian ini adalah 42,35 μg/dl, sedangkan rerata kadar SOD serum adalah 118,43 U/L. Analisis statistik dengan uji korelasi spearman menunjukan tidak terdapat hubungan yang signifikan antara kadar Pb darah dengan SOD serum (r = -0,263, p = 0,078).Kesimpulan: Kadar Pb darah tidak cukup mempengaruhi kadar SOD serum pada pasien Preeklampsia.
Perbandingan Model Pengembangan Perangkat Lunak Untuk Proyek Tugas Akhir Program Vokasi
Authors: Paksi Angger Binuko , Hafidhoh Nisa'ul , Bimonugroho Sigit Kariagil 
Published: June 2023

Salah satu syarat penyelesaian pendidikan pada perguruan tinggi adalah membuat tugas akhir. Hasil akhir dari tugas akhir pada perguruan tinggi vokasi diarahkan dalam bentuk produk atau alat. Untuk membuat produk perangkat lunak yang tersistematis maka dibutuhkan sebuah metodologi atau siklus pengembangan yang lebih dikenal dengan Software Development Life Cycle (SDLC). Secara umum SDLC memiliki beberapa tahapan yang dimulai dari tahap perencanaan, analisis, perancangan, implementasi, pengujian sampai pemeliharaan sistem. Kajian yang dilakukan adalah studi komparatif pada model pengembangan prototype, iterative dan agile. Perbandingan dari ketiga model tersebut menyatakan hasil bahwa model prototype membutuhkan perencanaan kebutuhan lebih matang dibanding kedua model lainnya, sedangkan model iterative dan model agile memiliki fleksibilitas lebih baik dalam menghadapi pengembangan ulang berjangka. Ketiga model cocok untuk perangkat lunak yang bersifat customizable, yang membedakan adalah kapan fase penyesuaian perubahan dilakukan. Dari kajian ketiga model didapatkan bahwa masing-masing mempunyai kelebihan dan kekurangan, sehingga pengembang dalam hal ini mahasiswa dapat menentukan model mana yang sesuai untuk pengembangan perangkat lunak proyek tugas akhir berdasarkan karakteristik setiap model.
Zkušenosti žáků s výukou ve výkonových skupinách: kvalitativní výzkumná sonda
Authors: Navrátilová Jana 
Published: June 2023

Cíle – Předkládaná studie je věnovaná problematice seskupování žáků v prostředí druhého stupně základních škol. Studie si klade za cíl popsat, jak žáci vypovídají o zkušenostech s výukou ve výkonových skupinách, a to především v porovnání s výukou, která probíhá v heterogenní třídě.
Metody – Studie je součástí projektu, který byl koncipován jako vícepřípadová studie mapující podobu seskupování žáků na druhém stupni ZŠ. V předloženém textu jsou prezentovány výsledky z jedné třídy, jedné základní školy, na které započalo výzkumné šetření. Studie vychází z dat získaných z individuálních (n=4) a párových rozhovorů (n=6) se žáky. Celkem je využito dat od 16 žáků.
Výsledky – Žáci z obou skupin jsou spokojenější ve výuce v homogenním seskupení na tolik, že preferují zintenzivnit výuku ve skupinách na úkor výuky ve společné třídě. Argumentují tím, že učitelé diferencují výuku pouze ve skupinách, které jsou k tomuto účelu údajně určeny. Výuka ve společné třídě diferencovaná podle žáků není. Optikou žáků se zdá, jako by učitelé centrovali svoje didaktické úsilí do kvality výuky ve skupinách a na diferencovanou výuku ve společné třídě zanevřeli. Ačkoli výuka ve výkonnostních skupinách lépe odpovídá vzdělávacím potřebám žáků v porovnání s výukou ve společné třídě, učitelé podle žáků někdy balancují nad tím, jakou míru podpory obě skupiny žáků potřebují. Tím, že učitelé výuku ve skupinách diferencují spíše podle očekávání o výkonech celé skupiny než podle skutečných výkonů jednotlivců, přestává výuka občas reagovat na individuální potřeby.
Závěry – Žákovský pohled ukazuje, že učitelé diferencují výuku spíše ve skupinách než ve společné třídě, nicméně v rámci skupiny již výuka diferencovaná není. Seskupení žáků do výkonových skupin může učitele svádět k užívání unifikovanějších didaktických postupů, které odpovídají potřebám a možnostem skupiny jako celku nikoli měnícím se potřebám jednotlivců uvnitř skupin.
Where to next with Australia’s News Media and Digital Platforms Mandatory Bargaining Code?
Authors: Dwyer Tim , Flew Terry , Wilding Derek 
Published: June 2023

Abstract
Taken at face value the introduction in 2021 of Australia’s News Media and Digital Platforms Mandatory Bargaining Code (“the Code”) may appear “world leading,” innovative, and, in general, a productive and strategic intervention to reverse the decline of public interest journalism. It is claimed that in the Australian news industry context, an annual transfer of around $200 million between two platform companies – Google and Meta – and news businesses has now been put in place (Sims, 2022). All major news media companies in Australia, if not smaller more independent ones, have greatly benefitted from the new Code, and anecdotally it appears that the funding has resulted in the creation of significant numbers of new journalists being hired. Yet the exact investment destination and ultimate beneficiaries of the funding are not known beyond the corporate walls of the recipients. The article points to the transparency and sustainability problems inherent to the new Code, arguing that an alternative approach to funding public interest journalism might be a levy funded by the platforms.
Pell-Lucas polynomials for numerical treatment of the nonlinear fractional-order Duffing equation
Authors: El-Sayed Adel Abd Elaziz 
Published: June 2023

AbstractThe nonlinear fractional-order cubic-quintic-heptic Duffing problem will be solved through a new numerical approximation technique. The suggested method is based on the Pell-Lucas polynomials’ operational matrix in the fractional and integer orders. The studied problem will be transformed into a nonlinear system of algebraic equations. The numerical expansion containing unknown coefficients will be obtained numerically via applying Newton’s iteration method to the claimed system. Convergence analysis and error estimates for the introduced process will be discussed. Numerical applications will be given to illustrate the applicability and accuracy of the proposed method.
Impacts of Brownian motion and fractional derivative on the solutions of the stochastic fractional Davey-Stewartson equations
Authors: Mohammed Wael W. , Al-Askar Farah M. , El-Morshedy Mahmoud 
Published: June 2023

Abstract
In this article, the stochastic fractional Davey-Stewartson equations (SFDSEs) that result from multiplicative Brownian motion in the Stratonovich sense are discussed. We use two different approaches, namely the Riccati-Bernoulli sub-ordinary differential equations and sine-cosine methods, to obtain novel elliptic, hyperbolic, trigonometric, and rational stochastic solutions. Due to the significance of the Davey-Stewartson equations in the theory of turbulence for plasma waves, the discovered solutions are useful in explaining a number of fascinating physical phenomena. Moreover, we illustrate how the fractional derivative and Brownian motion affect the exact solutions of the SFDSEs using MATLAB tools to plot our solutions and display a number of three-dimensional graphs. We demonstrate how the multiplicative Brownian motion stabilizes the SFDSE solutions at around zero.