bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nonlinear dynamics of a piezoelectrically laminated initially curved microbeam resonator exposed to out-of-plane electrostatic actuation
Authors: Azizi Saber , Rashidi Zahra , Rahmani Omid 
Published: March 2023

Abstract
In this paper the nonlinear dynamics of a piezoelectrically sandwiched initially curved microbeam subjected to out-of-plane electrostatic actuation is investigated. The governing motion equation is derived by minimising the Hamiltonian over the time and discretised to a reduced order model using Galerkin technique. The modelling accounts for nonlinear fringing field and mid plane stretching effect which appears as quadratic and cubic nonlinearities in the motion equation. The electrostatic force is numerically computed using finite element simulation. The nonlinear dynamics of the microbeam in the vicinity of primary resonance is investigated and the bifurcation types are determined by investigating the location of the Floquet exponents and their configuration with respect to the unit circle on the complex plane. The branches on the frequency response curves which originate from the period doubling bifurcation points are introduced and the transition from period-1 to period-2 response is demonstrated by slight sweep of the excitation frequency over the time. The effect of DC and AC electrostatic excitation as well as the piezoelectric excitation on the response of the system are examined and their effect on the bifurcation types are determined. The force response curves assuming the AC voltage as the bifurcation parameter are also introduced; It is illustrated that in contrast with in-plane electrostatic excitation, in fringing field-based resonators the resonator is not limited by Pull-in instability which is substantially confining the amplitude of the motion in in-plane resonators.
Platoon dispersion model in the mixed traffic environment
Authors: Cheng Wei , Chen Ye-xiao 
Published: March 2023

Abstract
To describe the law of platoon dispersion in the mixed traffic environment and provide a theoretical basis for signal timing optimization in the mixed traffic environment. Based on Robertson’s platoon dispersion model, this paper fully considers the characteristics of non-mixed conditions, and models the platoon dispersion in non-mixed traffic environment. Firstly, considering the influence of the percentage of non-motor vehicles on the platoon dispersion, the functional relationship between the percentage of non-motor vehicles and the parameters of the platoon dispersion model is derived, and the parameters of the Robertson platoon dispersion model are calibrated. Secondly, through the measured data of Zitai Road in Kunming City, the required model parameters are calculated, and the arrival flow rate distribution downstream of the intersection is obtained. Finally, according to the measured data, the proposed model is compared with the classical Robertson model. The results show that compared with the Robertson model, the average prediction mean square error of the proposed model is reduced by 5.89%, which can better describe the dispersion law of the mixed traffic under the influence of different percentage of non-motorized vehicles.
Measurements of Data Analytics Capability Construct
Authors: Rahman Nayem 
Published: March 2023

Abstract
Big data analytics has emerged as an important area of research in the big data domain. However, big data analytics capability empirical investigations have been hindered by the lack of psychometrically sound measurement items and scales. This paper reports approaches to the development and validation of new multi-item measurement scales reflecting a construct called data analytics capability. Data analytics capability reflects an organization's expertise in developing and deploying resources, usually in combination, to achieve the desired new insights that have business implications. This data analytics capability competence is operationalized as a multidimensional construct reflected by measurement items. In the first stage of measure development, we review the prominent information systems journals. We develop the construct items most of which are new items. Then we use industry experts and academicians to score them on a one to five scale. We also asked them to propose any new items. Based on their evaluation and scoring we finalize four items for this construct. Our results demonstrate that a reduced set of measurement items have reasonable psychometric properties and, therefore, are useful inputs for multi-item measurement scale development. In the second stage of measurement development, we conduct a survey of big data users via two online user groups. We received 349 valid responses which are analyzed using SPSS and AMOS statistical software. We successfully performed construct reliability analysis. The construct developed in this research may be used to advance scholarly understanding and theory in the big data and data analytics field.
Evaluation of the Relationship of Sleep Disturbances to Severity and Common Behaviors in Autism Spectrum Disorder
Authors: Miner Stacy , McVoy Molly , Damato Elizabeth 
Published: March 2023

Abstract
Background: Autism spectrum disorder (ASD) is one of the most puzzling disorders of childhood. Recent research of comorbidities that accompany ASD and are commonly attributed to the diagnosis, indicate that they may contribute to the severity of behavioral symptoms of the disorder.
Disturbed sleep in all children can decrease cognition, decrease focus, increase performance problems, and alter mood and behavior. Children with ASD experience an increased sensitivity to disturbed sleep that may increase the severity of the disorder. Disturbed sleep patterns, such as increased sleep latency, nighttime waking and early arousal, have been identified in up to 80% of children with ASD. This study explored the relationship of disturbed sleep and the severity of the core ASD symptoms.
Methods: Actigraphy and an accompanying sleep diary captured disturbed sleep patterns in 24 children, ages 6-12, with ASD. Participants wore a GT3X actigraphy monitor for 7 nights to collect data on patterns of disturbed sleep. Parents completed a sleep diary and the Autism Spectrum Rating Scale (ASRS) questionnaire.
A descriptive analysis was used to report the characteristics of nighttime sleep and sleep efficiency as well as sleep disturbances. Pearson’s r determined the relationships between the number of sleep disturbances and the severity of ASD behavioral scores and diagnostic severity (determined by the ASRS).
Results: Of the 24 study participants, almost 92% had one or more sleep disturbances. A positive correlation was present between the number of sleep disturbances and the severity of delays in social and communication symptoms. A moderate effect size was found between the number of sleep disturbances and unusual behaviors in ASD suggests a possible, unanticipated, inverse relationship.
Conclusions: Exploring the relationship of disturbed sleep to behavior and symptom severity in children with ASD can provide an understanding of how poor sleep influences ASD symptoms. This study identified distinct differences in ASD symptom severity between and within individual participants and found unique, and unexpected, symptom patterns. This finding supports the need, in research and treatment, to identify comorbidities and symptoms that contribute to individual behavioral profiles and phenotypes of the disorder.
Weekly change in serum β-human chorionic gonadotropin, estradiol, and progesterone levels for pregnancy assessment in women with unexplained recurrent miscarriage
Authors: Su Ruide , Wang Yan , Lu Ye , Lin Bizhu , An Jian 
Published: March 2023

Abstract

Objective
To investigate the efficacy of weekly changes in β-human chorionic gonadotropin (β-hCG), estradiol (E2), and progesterone (Prog) levels for pregnancy assessment in patients with unexplained recurrent miscarriage.
Methods
We included 140 patients with unexplained recurrent miscarriage whose serum β-hCG, E2, and Prog levels were measured three or more times within early pregnancy. The weekly change in serum β-hCG, E2, and Prog levels (Δβ-hCG, ΔE2, and ΔProg) was calculated according to the following formula: [(serum level at third visit) - (serum level at initial visit)]/interval days×7. Participants were divided into two groups according to pregnancy outcomes, which were determined as ongoing pregnancy or miscarriage, at the 20th week of gestation. The Δβ-hCG, ΔE2, and ΔProg levels of the two groups were compared, and the cutoff values of Δβ-hCG, ΔE2, and ΔProg were determined using receiver operating characteristic (ROC) analyses for predicting pregnancy outcome.
Results
Serum levels of Δβ-hCG identified ongoing pregnancy or miscarriage with an area under the ROC curve (AUC) of 0.841 (95% CI 0.769–0.914), diagnostic cutoff value of 30,632.855 mIU/ml, sensitivity of 0.971, and specificity of 0.642. ΔE2 levels had an AUC of 0.839 (95% CI 0.752–0.926), cutoff value of 45.055 pg/ml, sensitivity of 0.706, and specificity of 0.915.
Conclusion
Higher increases in the serum levels of Δβ-hCG and ΔE2 are associated with favorable pregnancy outcomes. Weekly remeasurement of serum β-hCG and E2 may be useful for pregnancy risk assessment in patients with unexplained recurrent miscarriage throughout clinical practice.
Human cortical, muscular, and kinematic gait adaptation with novel use of an ankle exoskeleton
Authors: Song Seongmi , Haynes Courtney A. , Bradford J. Cortney 
Published: March 2023

Abstract
Walking with an exoskeleton is a complex task that requires human and machine integration. Previous studies focused on metabolic consumption, muscle activations, kinetic and kinematic changes, and adaption during exoskeleton-assisted walking. However, limited information is available on cortical changes and adaptations during walking with an exoskeleton. Our study aims to better understand human cortical responses and adaptation to walking with an ankle exoskeleton. We included healthy, novice users without prior exoskeleton experience and collected EEG (electroencephalography), EMG (electromyography), and full body motion capture while walking at a speed of 1.2m/s. When experiencing exoskeleton-assisted walking for the first time, subjects showed reduced joint range of motion and stride length along with increased step width, even while muscle activation was decreased. The cortical response also follows the decreased balance, showing theta power increase in the left prefrontal, right sensorimotor, and right somatosensory cortex. Over time, the results showed increased balance, greater reduction in muscle activity, and reduced cortical engagement while walking with exoskeleton assistance. Yet, we also observed adaptation to walking with exoskeleton frames over time. These findings could provide information to develop more effective and intuitive augmentation devices that are better able to integrate with human movements.
Fabrication of hydrophobic surface on eri silk/ wool fabric using nano silica extracted from rice husk
Authors: Borah Mamoni Probha , Kalita Binita Baishya , Jose Seiko , Baruah Sunita 
Published: March 2023

AbstractSilica nano particles were synthesized from rice husk by alkali treatment followed by calcination. The nano particles were characterized with the aid of Fourier Transform Infrared Spectroscopy (FTIR), Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM) and X-ray Diffraction Spectroscopy (XRD). The eri silk / wool union fabric was coated with the nano silica by hydrothermal method for achieving hydrophobic surface. The SEM and XRD results inferred that the synthesized silica nano particles are spherical and amorphous in nature. SEM, EDX, and Atomic Absorption Spectroscopy (AAS) analyses qualitatively and quantitatively verified the presence of nano silica on the fabric. The nano silica treatment resulted in the enhancement of water contact angle upto 145○. The results are further confirmed by spray test and water absorbency analysis. The nano silica treated fabric possessed good fastness to dry cleaning and washing. The highest contact angle of 145○was observed with the treatment of union fabric with 7.5% nano silica. The AAS results showed 667 ppm of silica on the fabric. The physico-mechanical properties of the silica treated fabric marked marginal difference with the untreated fabric.
Diffuse reflectance spectroscopy for predicting age, species, and insecticide resistance of the malaria mosquito Anopheles gambiae s.l
Authors: Betancourth Mauro Pazmiño , Ochoa-Gutiérrez Victor , Ferguson Heather M. , González-Jiménez Mario , Wynne Klaas , Baldini Francesco , Childs David 
Published: March 2023

Abstract
Mid-infrared spectroscopy (MIRS) combined with machine learning analysis has shown potential for quick and efficient identification of mosquito species and age groups. However, current technology to collect spectra is destructive to the sample and does not allow targeting specific tissues of the mosquito, limiting the identification of other important biological traits such as insecticide resistance. Here, we assessed the use of a non-destructive approach of MIRS for vector surveillance, micro diffuse reflectance spectroscopy (µDRIFT) using mosquito legs to identify species, age and cuticular insecticide resistance within the Anopheles gambiae s.l. complex. These mosquitoes are the major vectors of malaria in Africa and the focus on surveillance in malaria control programs. Legs required significantly less scanning time and showed more spectral consistence compared to other mosquito tissues. Machine learning models were able to identify An. gambiae and An. coluzzii with an accuracy of 0.73, two ages groups (3 and 10 days old) with 0.77 accuracy and we obtained accuracy of 0.75 when identifying cuticular insecticide resistance. Our results highlight the potential of different mosquito tissues and µDRIFT as tools for biological trait identification on mosquitoes that transmit malaria. These results can guide new ways of identifying mosquito traits which can help the creation of innovative surveillance programs by adapting new technology into mosquito surveillance and control tools.
Adult-onset Alexander disease in people living with HIV and a novel mutation in GFAP
Authors: Guo Yongzheng , Peng Xiaorong , Zhou Xiaotang , Zhu Biao 
Published: March 2023

Abstract
Background: Alexander disease (AD) is a rare and fatal leukoencephalopathy that is diagnosed based on clinical symptoms, typical MRI findings, and mutations in the glial fibrillary acid protein (GFAP) gene. However, no case has been reported on adult-onset Alexander disease (AOAD) in people living with HIV (PLWH).
Case presentation: A 43-year-old male patient experienced a progressive gait disorder and generalized muscle weakness. He was diagnosed HIV-positive ten years ago with viral suppression. Conventional microbiological tests and Metagenomic next-generation sequencing in cerebrospinal fluid were negative. Brain T2-weighted image showed marked thinning of the medulla and upper cervical spinal cord (tadpole sign). A heterozygous 206A→T mutation was confirmed in GFAP exon 1. The patient’s family consisted of three generations with two affected individuals. The clinically affected mother (I.1) and unaffected sister (II.1) and daughter (III.1) had the 206A→T heterozygous mutation, whereas the remaining two siblings and son did not harbor the mutation.
Conclusions: In summary, this is the first report of AOAD in PLWH. AOAD should be considered in PLWH that exhibit uncommon neurological diseases.
Soil microbial dark matter explored from genome-resolved metagenomics
Authors: Ma Bin , Lu Caiyu , Wang Yiling , Yu Jingwen , Zhao Kankan , Xue Ran , Lv Xiaofei , Pan Ronghui , Zhang Jiabao , Zhu Yong-Guan , Xu Jianming 
Published: March 2023

Abstract
Soil contains a vast number of unidentified microbes, known as soil microbial dark matter. This is an important source of microbial biodiversity and genetic resources1,2, but has yet to be fully explored. In this study, we conducted the first large-scale excavation of soil microbial dark matter by reconstructing 40,039 metagenome-assembled genome bins (the SMAG catalog) from 3,463 soil metagenomes. We identified 16,530 of 21,077 species-level genome bins (SGBs) as unknown SGBs (uSGBs), which greatly expand archaeal and bacterial diversity across the tree of life. The uSGBs identified substantially increased the functional landscape and intra-species genome diversity of the soil microbiome, and provided large proportions of the 43,169 biosynthetic gene clusters and 8,544 CRISPR-Cas genes mined from the SMAG catalog. This suggests their potential for genetic resource exploitation. In addition, we determined that uSGBs contributed 84.6% of novel viral-host associations identified from the SMAG catalog. Our results demonstrate the richness of microbial dark matter in soil and highlight its potential. Furthermore, the SMAG catalog will serve as a valuable genomic database for understanding soil microbial biodiversity and exploiting novel genetic resources.
Association between Depression, Anemia And Physical activity Using Isotemporal Substitution Analysis
Authors: Nam Hee-kyoung , Park Jungmi , Cho Sung-il 
Published: March 2023

Abstract

Background:Depression is a leading cause of disability and mortality, with estimated number of deaths exceeding 2.2 million worldwide. We examined depression in relation to anemia and physical activity, both of which have an impact on depression mechanisms.Methods:This cross-sectional study used data from the Korean National Health and Nutrition Examination Survey was utilized including 18622 participants. Depression was measured by The Patient Health Questionnaire-9, and physical activity was assessed by the Global Physical Activity Questionnaire. Anemia was defined by World Health Organization criteria for blood hemoglobin levels. Isotemporal substitution model for physical activity was used to assess the effect of replacing each intensity level of physical activity. Logistic regression was applied to estimate the effects on depression.Results:Replacing sedentary behavior with moderate or vigorous physical activity was associated with a lower risk of depression in the anemic (OR: 0.875, 95% CI: 0.782–0.978) and non-anemic groups (OR: 0.943, 95% CI: 0.919–0.967). Depression risk was significantly reduced by replacing walking with moderate to vigorous physical activity in both anemic (OR: 0.877, 95% CI: 0.784–0.982) and non-anemic groups (OR: 0.951, 95% CI: 0.927–0.976).Conclusions:Moderate to vigorous physical activity had a protective effect against depression in both anemic and non-anemic groups. Physical activity should be performed to prevent depression in individuals with anemia.
The Benefits of Early Continuous Renal Replacement Therapy in Critically Ill Patients with Acute Kidney Injury at High-Altitude Areas: A Retrospective Multi-center Cohort Study
Authors: Wang Bowen , Peng Mengjia , Wei Hui , Liu Chang , Wang Juan , Jiang Liheng , Fang Fei , Wang Yuliang , Shen Yuandi 
Published: March 2023

Abstract
Severe hypoxia would aggravate the acute kidney injure (AKI) in high-altitude areas and continuous renal replacement therapy (CRRT) has been used to treat critically ill patients with AKI. However, the characteristics and outcomes of CRRT of critically ill patients with AKI in high altitude and the optimal timing of CRRT initiation are still unclear. 1,124 patients were diagnosed with AKI and treated with CRRT in ICU, involving high-altitude group (n = 648) and low-altitude group (n = 476). Compared with low-altitude group, patients with AKI in high altitude showed longer CRRT (4.8 vs. 3.7, P = 0.036) and more rapid progression of AKI stages (P < 0.01), but without any significance of minor or major bleeding episode (P > 0.05). Referring to the analysis of survival and kidney recovery curves, a higher mortality but a lower possibility of renal recovery was observed in high-altitude group (P < 0.001). However, in the high-altitude group, the survival rate of early CRRT initiation was significantly higher than that of delayed CRRT initiation (P < 0.001). The findings showed poorer clinical outcomes of patients undergoing CRRT for AKI in high altitude. CRRT at high altitude was unlikely to increase the adverse events. Moreover, early CRRT initiation might reduce the mortality and promote renal recovery in high-altitude patients.
Divergent brain regional atrophy and associated fiber disruption in amnestic and non-amnestic MCI
Authors: Chen Yaojing , Du Chao , Dang Mingxi , Chen Kewei , Zhang Zhanjun 
Published: March 2023

Abstract
Background: Understanding the pathological characteristics of various subtypes of mild cognitive impairment (MCI) is crucial for the differential diagnosis of dementia. The purpose of this study was to feature divergent symptom-deficit profiles in amnestic MCI (aMCI) and non-amnestic MCI (naMCI).
Methods: T1 and DTI MRI data from a total of 158 older adults with 50 normal controls, 56 aMCI and 52 naMCI were included. The voxel-wise gray matter volumes and the number of seed-based white matter fiber bundles were compared between these groups. Further, correlation and mediation analyses between the neuroimaging indices and cognitive performance indices were performed.
Results: The aMCI with specific memory abnormalities was characterized by volumetric atrophy of the left hippocampus but not by differences in linked white matter fiber bundles. Conversely, naMCI was characterized by altered volume of the right inferior frontal gyrus with significant damage to fiber bundles traversing the region in all three directions, not only affecting fibers around the atrophied area but also distant fibers. Mediation analyses of gray matter-white matter-cognition showed that gray matter atrophy affects the number of fiber bundles and further affects attention and executive function. Meanwhile, fiber bundle damage also affects gray matter volume, which further affects visual processing and language.
Conclusions: The divergent structural damage patterns of the MCI subtypes and cognitive dysfunctions highlights the importance of detailed differential diagnoses in the early stages of pathological neurodegenerative diseases to deepen understanding of dementia subtypes and inform targeted early clinical interventions.
Tongue Necrosis Secondary to Giant Cell Arteritis, Successfully Treated with Tocilizumab: A Case Report
Authors: Cho Young Min , Khoury Lara El , Paramo Jonathan , Horowitz Diane Michelle , Li Jian Yi , Kello Nina 
Published: March 2023

Abstract
Background: Giant Cell Arteritis (GCA) is a large vessel vasculitis that most commonly presents with headache, scalp tenderness, jaw claudication, and vision changes. Various other, less common, manifestations have been reported in the literature such as scalp and tongue necrosis. Though most patients respond to corticosteroids, some cases of GCA are refractory to the high doses of corticosteroids.
Case presentation: We present a 73-year-old female with GCA refractory to corticosteroids presenting with tongue necrosis. This patient significantly improved with a dose of tocilizumab, an IL-6 inhibitor.
Conclusion: To the best of our knowledge, this is the first case report of a patient with refractory GCA presenting with tongue necrosis that had rapid improvement with tocilizumab.