bluuebunny/crossref_metadata_2025_split huggingface dataset:
‘I think this is where this lovely word “sustainability” comes in’: Fruit and vegetable growers' narratives concerning the regulation of environmental water use for food production
Authors: Sutcliffe Chloe , Knox Jerry , Hess Tim 
Published: May 2023

AbstractThis article concerns UK commercial fruit and vegetable growers’ narratives regarding the sustainability of water use for food production. In it we explore their perspectives on efforts by regulators to limit agricultural withdrawals of water from the natural environment in line with EU Water Framework Directive objectives, alongside their views on retailer sustainability commitments. Discourse analysis is used to investigate how the growers contested restrictive regulation, constructed their identities, portrayed other supply chain stakeholders, and conveyed their social relations with them. Using Erving Goffman's theory of frontstage and backstage performances, the implications for the growers’ water management decisions and their internalisation of sustainability agendas for water are examined. Whilst the growers gave accounts of purposely misrepresenting their water withdrawal practices and their discourse illustrated significant polarisation between environmental and agricultural interests, their underlying commitment to environmental sustainability was ambivalent, with both anti and pro‐environmental attitudes expressed. The growers also frequently gave critiques of superficial sustainability in fresh produce supply chains. We argue that, given contemporary shifting definitions of agricultural identities, settings in which their construction is negotiated can provide windows of opportunity for conventional growers to engage in genuine pro‐environmental performances that may deepen their assimilation of environmental goals and commitment to sustainable water use.
GIS‐enabled historiography to determine travel routes during the Western Han period via agent‐based models and least‐cost path analysis
Authors: Sengupta Raja , Vankeerberghen Griet , Wen Ruoxuan , Rao Jing , Chen Yanbing 
Published: May 2023

AbstractGIS‐enabled historiography allows us to shed light on missing or poorly understood aspects of historical events. Here, we use agent‐based models (ABMs), least cost path analysis (LCPA), and space–time paths to recreate and evaluate possible modes and routes of travel undertaken by Shi Rao, a Western Han official. A diary was found in Shi Rao's tomb that includes information about his travels over 1 year (11 BCE), including start and end times of his journeys. But it leaves out details regarding modes of transport or exact routes. Using Tan Qixiang's historical atlas, we digitized river networks and utilized modern topographic data to digitally recreate the landscape as it was during Shi Rao's travels. This was then used to evaluate possible journeys via rivers (using ABMs) and roads (using LCPA), and compared to historical speed of boats, carts and horses, with findings indicating that horseback may have been the viable option.
Strategies to improve antiretroviral therapy (ART) initiation and early engagement among men insub‐SaharanAfrica: A scoping review of interventions in the era of universal treatment
Authors: Dovel Kathryn L. , Hariprasad Santhi , Hubbard Julie , Cornell Morna , Phiri Khumbo , Choko Augustine , Abbott Rachel , Hoffman Risa , Nichols Brooke , Gupta Sundeep , Long Lawrence 
Published: May 2023

AbstractObjectivesMen in sub‐Saharan Africa (SSA) have lower rates of antiretroviral therapy (ART) initiation and higher rates of early default than women. Little is known about effective interventions to improve men's outcomes. We conducted a scoping review of interventions aimed to increase ART initiation and/or early retention among men in SSA since universal treatment policies were implemented.MethodsThree databases, HIV conference databases and grey literature were searched for studies published between January 2016 to May 2021 that reported on initiation and/or early retention among men. Eligibility criteria included: participants in SSA, data collected after universal treatment policies were implemented (2016–2021), quantitative data on ART initiation and/or early retention for males, general male population (not exclusively focused on key populations), intervention study (report outcomes for at least one non‐standard service delivery strategy), and written in English.ResultsOf the 4351 sources retrieved, 15 (reporting on 16 interventions) met inclusion criteria. Of the 16 interventions, only two (2/16, 13%) exclusively focused on men. Five (5/16, 31%) were randomised control trials (RCT), one (1/16, 6%) was a retrospective cohort study, and 10 (10/16, 63%) did not have comparison groups. Thirteen (13/16, 81%) interventions measured ART initiation and six (6/16, 37%) measured early retention. Outcome definitions and time frames varied greatly, with seven (7/16, 44%) not specifying time frames at all. Five types of interventions were represented: optimising ART services at health facilities, community‐based ART services, outreach support (such as reminders and facility escort), counselling and/or peer support, and conditional incentives. Across all intervention types, ART initiation rates ranged from 27% to 97% and early retention from 47% to 95%.ConclusionsDespite years of data of men's suboptimal ART outcomes, there is little high‐quality evidence on interventions to increase men's ART initiation or early retention in SSA. Additional randomised or quasi‐experimental studies are urgently needed.
Implications of Grounded Cognition for Conceptual Processing Across Cultures
Authors: Barsalou Lawrence W. 
Published: May 2023

AbstractCross‐linguistic differences in concepts have implications for all theories of concepts, not just for grounded ones. Failure to address these implications does not imply the belief that they do not exist. Instead, it reflects a division of labor between researchers who focus on general principles versus cultural variability. Furthermore, core principles of grounded cognition—empirical learning and situated conceptual processing—predict large cultural differences in conceptual systems. If asked, most grounded cognition researchers would anticipate and endorse these differences, as would most researchers from other perspectives. Finally, by incorporating ethnographic and linguistic analysis, grounded cognition researchers can examine how cultural differences manifest themselves in conceptual systems.
Experimental and Computational Investigation of Shaped Film Cooling Holes Designed to Minimize Inlet Separation
Authors: Jones Fraser B. , Fox Dale W. , Bogard David G. 
Published: May 2023

Abstract
Film cooling is used to protect turbine components from the extreme temperatures by ejecting coolant through arrays of holes to create an air buffer from the hot combustion gases. Limitations in traditional machining meant film cooling holes universally have sharp inlets, which create separation regions at the hole entrance. The present study uses experimental and computational data to show that these inlet separation are a major cause of performance variation in crossflow fed film cooling holes. Three-hole designs were experimentally tested by independently varying the coolant velocity ratio (VR) and the coolant channel velocity ratio (VRc) to isolate the effects of crossflow on hole performance. Leveraging additive manufacturing (AM) technologies, the addition of a 0.25D radius fillet to the inlet of a 7-7-7 shaped hole is shown to significantly improve diffuser usage and significantly reduce variation in performance with VRc. A second AM design used a very large radius of curvature inlet to reduce biasing caused by the inlet crossflow. Experiments showed that this “swept” hole design did minimize biasing of the coolant flow to one side of the shaped hole, and it significantly reduced variations due to varying VRc. RANS simulations at six VR and three VRc conditions were made for each geometry to better understand how the new geometries changed the velocity field within the hole. The sharp and rounded inlets were seen to have very similar tangential velocity fields and jet biasing. Both AM inlets created more uniform, slower velocity fields entering the diffuser. The results of this article indicate that large improvements in film cooling performance can be found by leveraging AM technology.
Use of interviewer-administered telephone surveys during infectious disease outbreaks, epidemics and pandemics: a scoping review
Authors: Arita Sayaka , Ba Mouhamadou Faly , Traoré Zoumana , Bonnet Emmanuel , Faye Adama , Ridde Valéry 
Published: May 2023

IntroductionDuring the COVID-19 crisis, researchers had to collect data remotely. Telephone surveys and interviews can quickly gather data from a distance without heavy expense. Although interviewer-administered telephone surveys (IATS) can accommodate the needs of international public health research, the literature on their use during infectious disease outbreaks is scarce. This scoping review aimed to map the characteristics of IATS during infectious disease outbreaks.MethodsIATS conducted principally during infectious disease outbreaks and answered by informants at least 18 years old were searched from PubMed and EBSCO. There was a manual addition of relevant documents identified during an initial search. Overall trends were reported using different groupings, including WHO regions, and study details were compared before and during the COVID-19 pandemic.Results70 IATS published between 2003 and 2022 were identified. 57.1% were conducted during the COVID-19 pandemic. Among 30 IATS conducted before the COVID-19 pandemic in the world, only 3.3% were carried out in low-income and middle-income countries (LMICs). This percentage of studies in LMICs out of all the IATS rose to 32.5% during the pandemic. The share of qualitative studies grew from 6.7% before the COVID-19 outbreak to 32.5% during the outbreak. IATS performed during the COVID-19 pandemic focused on more diverse, specific population groups, such as patients and healthcare professionals. Mobile phones are increasingly used for IATS over time.ConclusionIATS are used globally with high frequency in the Western Pacific Region and high-income countries. Technical and financial challenges continue to exist, and assessments of inclusiveness and representativeness should be carefully conducted. A lack of details related to methods was observed, and this scoping review urges researchers using this data collection method in the future to specify how they executed IATS for better use and more efficient deployment.
Protocol for the BONE-RECON trial: a single-arm feasibility trial for critical sized lower limb BONE defect RECONstruction using the mPCL-TCP scaffold system with autologous vascularised corticoperiosteal tissue transfer
Authors: Sparks David S , Wiper Jay , Lloyd Thomas , Wille Marie-Luise , Sehu Marjoree , Savi Flavia M , Ward Nicola , Hutmacher Dietmar W , Wagels Michael 
Published: May 2023

IntroductionReconstruction of critical bone defects is challenging. In a substantial subgroup of patients, conventional reconstructive techniques are insufficient. Biodegradable scaffolds have emerged as a novel tissue engineering strategy for critical-sized bone defect reconstruction. A corticoperiosteal flap integrates the hosts’ ability to regenerate bone and permits the creation of a vascular axis for scaffold neo-vascularisation (regenerative matching axial vascularisation—RMAV). This phase IIa study evaluates the application of the RMAV approach alongside a custom medical-grade polycaprolactone-tricalcium phosphate (mPCL-TCP) scaffold (Osteopore) to regenerate bone sufficient to heal critical size defects in lower limb defects.Methods and analysisThis open-label, single-arm feasibility trial will be jointly coordinated by the Complex Lower Limb Clinic (CLLC) at the Princess Alexandra Hospital in Woolloongabba (Queensland, Australia), the Australian Centre for Complex Integrated Surgical Solutions (Queensland, Australia) and the Faculty of Engineering, Queensland University of Technology in Kelvin Grove (Queensland, Australia). Aiming for limb salvage, the study population (n=10) includes any patient referred to the CLLC with a critical-sized bone defect not amenable to conventional reconstructive approaches, after discussion by the interdisciplinary team. All patients will receive treatment using the RMAV approach using a custom mPCL-TCP implant. The primary study endpoint will be safety and tolerability of the reconstruction. Secondary end points include time to bone union and weight-bearing status on the treated limb. Results of this trial will help shape the role of scaffold-guided bone regenerative approaches in complex lower limb reconstruction where current options remain limited.Ethics and disseminationApproval was obtained from the Human Research Ethics Committee at the participating centre. Results will be submitted for publication in a peer-reviewed journal.Trial registration numberACTRN12620001007921.
Protocol for a pragmatic cluster randomised controlled trial assessing the clinical effectiveness and cost-effectiveness of Electronic RIsk-assessment for CAncer for patients in general practice (ERICA)
Authors: Hamilton Willie , Mounce Luke , Abel Gary A , Dean Sarah Gerard , Campbell John L , Warren Fiona C , Spencer Anne , Medina-Lara Antonieta , Pitt Martin , Shephard Elizabeth , Shakespeare Marijke , Fletcher Emily , Mercer Adrian , Calitri Raff 
Published: May 2023

IntroductionThe UK has worse cancer outcomes than most comparable countries, with a large contribution attributed to diagnostic delay. Electronic risk assessment tools (eRATs) have been developed to identify primary care patients with a ≥2% risk of cancer using features recorded in the electronic record.Methods and analysisThis is a pragmatic cluster randomised controlled trial in English primary care. Individual general practices will be randomised in a 1:1 ratio to intervention (provision of eRATs for six common cancer sites) or to usual care. The primary outcome is cancer stage at diagnosis, dichotomised to stage 1 or 2 (early) or stage 3 or 4 (advanced) for these six cancers, assessed from National Cancer Registry data. Secondary outcomes include stage at diagnosis for a further six cancers without eRATs, use of urgent referral cancer pathways, total practice cancer diagnoses, routes to cancer diagnosis and 30-day and 1-year cancer survival. Economic and process evaluations will be performed along with service delivery modelling. The primary analysis explores the proportion of patients with early-stage cancer at diagnosis. The sample size calculation used an OR of 0.8 for a cancer being diagnosed at an advanced stage in the intervention arm compared with the control arm, equating to an absolute reduction of 4.8% as an incidence-weighted figure across the six cancers. This requires 530 practices overall, with the intervention active from April 2022 for 2 years.Ethics and disseminationThe trial has approval from London City and East Research Ethics Committee, reference number 19/LO/0615; protocol version 5.0, 9 May 2022. It is sponsored by the University of Exeter. Dissemination will be by journal publication, conferences, use of appropriate social media and direct sharing with cancer policymakers.Trial registration numberISRCTN22560297.
Comparison of hearing aid fitting effectiveness with audiograms from either user-operated or traditional audiometry in a clinical setting: a study protocol for a blinded non-inferiority randomised controlled trial
Authors: Pedersen Carl Christian , Pedersen Ellen Raben , Laugesen Søren , Sanchez-Lopez Raul , Nielsen Jacob , Sørensen Chris Bang , Sidiras Christos , Pedersen René Gyldenlund , Schmidt Jesper Hvass 
Published: May 2023

IntroductionThere is a worldwide need to enhance the capacity of audiometry testing. The objective of this study is to compare the User-operated Audiometry (UAud) system with traditional audiometry in a clinical setting, by investigating if hearing aid effectiveness based on UAud is non-inferior to hearing aid effectiveness based on traditional audiometry, and whether thresholds obtained with the user-operated version of the Audible Contrast Threshold (ACT) test correlates to traditional measures of speech intelligibility.Methods and analysisThe design will be a blinded non-inferiority randomised controlled trial. 250 adults referred for hearing aid treatment will be enrolled in the study. Study participants will be tested using both traditional audiometry as well as the UAud system and they will answer the questionnaire Speech, Spatial and Qualities of Hearing Scale (SSQ12) at baseline. Participants will be randomly divided to receive hearing aids fitted based on either UAud or traditional audiometry. Three months after participants have started using their hearing aids, they will undergo a hearing in noise test with hearing aids to measure their speech-in-noise performance and answer the following questionnaires: SSQ12, the Abbreviated Profile of Hearing Aid Benefit and the International Outcome Inventory for Hearing Aids. The primary outcome is a comparison of the change in SSQ12 scores from baseline to follow-up between the two groups. Participants will undergo the user-operated ACT test of spectro-temporal modulation sensitivity as part of the UAud system. The ACT results will be compared with measures of speech intelligibility from the traditional audiometry session and follow-up measurements.Ethics and disseminationThe project was evaluated by the Research Ethics Committee of Southern Denmark and judged not to need approval. The findings will be submitted to an international peer-reviewed journal and presented at national and international conferences.Trial registration numberNCT05043207.
Sexual health promotion for sexual and gender minorities in primary care: a scoping review protocol
Authors: Homme Paige , Truong Robinson , Gong Jenny , Ziegler Carolyn , Freitas Cassandra , Yeung Anna , Tan Darrell HS , Burchell Ann N 
Published: May 2023

IntroductionSexual and gender minorities (SGMs) face health disparities related to systemic discrimination and barriers to sexual health. Sexual health promotion encompasses strategies that enable individuals, groups and communities to make informed decisions regarding their sexual well-being. Our objective is to describe the existing sexual health promotion interventions tailored for SGMs within the primary care context.Methods and analysisWe will conduct a scoping review and search for articles in 12 medical and social science academic databases on interventions that are targeted towards SGMs in the primary care context in industrialised countries. Searches were conducted on 7 July 2020 and 31 May 2022. We defined sexual health interventions in the inclusion framework as: (1) promote positive sexual health, or sex and relationship education; (2) reduce the incidence of sexually transmitted infections; (3) reduce unintended pregnancies; or (4) change prejudice, stigma and discrimination around sexual health, or increase awareness surrounding positive sex. Two independent reviewers will select articles meeting inclusion criteria and extract data. Participant and study characteristics will be summarised using frequencies and proportions. Our primary analysis will include a descriptive summary of key interventional themes from content and thematic analysis. Gender-based Analysis Plus will be used to stratify themes based on gender, race, sexuality and other identities. The secondary analysis will include the use of the Sexual and Gender Minority Disparities Research Framework to analyse the interventions from a socioecological perspective.Ethics and disseminationNo ethical approval is required for a scoping review. The protocol was registered on the Open Science Framework Registries (https://doi.org/10.17605/OSF.IO/X5R47). The intended audiences are primary care providers, public health, researchers and community-based organisations. Results will be communicated through peer-reviewed publication, conferences, rounds and other opportunities to reach primary care providers. Community-based engagement will occur through presentations, guest speakers, community forums and research summary handouts.
Effectiveness of digital adherence technologies in improving tuberculosis treatment outcomes in four countries: a pragmatic cluster randomised trial protocol
Authors: Jerene Degu , Levy Jens , van Kalmthout Kristian , Rest Job van , McQuaid Christopher Finn , Quaife Matthew , Charalambous Salome , Gamazina Katya , Garfin A M Celina , Mleoh Liberate , Terleieva Yana , Bogdanov Alexsey , Maraba Noriah , Fielding Katherine 
Published: May 2023

IntroductionSuccessful treatment of tuberculosis depends to a large extent on good adherence to treatment regimens, which relies on directly observed treatment (DOT). This in turn requires frequent visits to health facilities. High costs to patients, stigma and burden to the health system challenged the DOT approach. Digital adherence technologies (DATs) have emerged as possibly more feasible alternatives to DOT but there is conflicting evidence on their effectiveness and feasibility. Our primary objective is to evaluate whether the implementation of DATs with daily monitoring and a differentiated response to patient adherence would reduce poor treatment outcomes compared with the standard of care (SOC). Our secondary objectives include: to evaluate the proportion of patients lost to follow-up; to compare effectiveness by DAT type; to evaluate the feasibility and acceptability of DATs; to describe factors affecting the longitudinal engagement of patients with the intervention and to use a simple model to estimate the epidemiological impact and cost-effectiveness of the intervention from a health system perspective.Methods and analysisThis is a pragmatic two-arm cluster-randomised trial in the Philippines, South Africa, Tanzania and Ukraine, with health facilities as the unit of randomisation. Facilities will first be randomised to either the DAT or SOC arm, and then the DAT arm will be further randomised into medication sleeve/labels or smart pill box in a 1:1:2 ratio for the smart pill box, medication sleeve/label or the SOC respectively. We will use data from the digital adherence platform and routine health facility records for analysis. In the main analysis, we will employ an intention-to-treat approach to evaluate treatment outcomes.Ethics and disseminationThe study has been approved by the WHO Research Ethics Review Committee (0003296), and by country-specific committees. The results will be shared at national and international meetings and will be published in peer-reviewed journals.Trial registration numberISRCTN17706019.