bluuebunny/crossref_metadata_2025_split huggingface dataset:
Schrödinger Operators with Oblique Transmission Conditions in $${\mathbb R}^2$$
Authors: Behrndt Jussi , Holzmann Markus , Stenzel Georg 
Published: May 2023

AbstractIn this paper we study the spectrum of self-adjoint Schrödinger operators in $$L^2(\mathbb {R}^2)$$

L
2

(

R

2

)

with a new type of transmission conditions along a smooth closed curve $$\Sigma \subseteq \mathbb {R}^2$$

Σ
⊆

R

2

. Although these oblique transmission conditions are formally similar to $$\delta '$$

δ
′

-conditions on $$\Sigma $$
Σ
(instead of the normal derivative here the Wirtinger derivative is used) the spectral properties are significantly different: it turns out that for attractive interaction strengths the discrete spectrum is always unbounded from below. Besides this unexpected spectral effect we also identify the essential spectrum, and we prove a Krein-type resolvent formula and a Birman-Schwinger principle. Furthermore, we show that these Schrödinger operators with oblique transmission conditions arise naturally as non-relativistic limits of Dirac operators with electrostatic and Lorentz scalar $$\delta $$
δ
-interactions justifying their usage as models in quantum mechanics.
Application of machine learning algorithm in prediction of lymph node metastasis in patients with intermediate and high-risk prostate cancer
Authors: Wang Xiangrong , Zhang Xiangxiang , Li Hengping , Zhang Mao , Liu Yang , Li Xuanpeng 
Published: May 2023

Abstract
Purpose
This study aims to establish the best prediction model of lymph node metastasis (LNM) in patients with intermediate- and high-risk prostate cancer (PCa) through machine learning (ML), and provide the guideline of accurate clinical diagnosis and precise treatment for clinicals.

Methods
A total of 24,470 patients with intermediate- and high-risk PCa were included in this study. Multivariate logistic regression model was used to screen the independent risk factors of LNM. At the same time, six algorithms, namely random forest (RF), naive Bayesian classifier (NBC), xgboost (XGB), gradient boosting machine (GBM), logistic regression (LR) and decision tree (DT) are used to establish risk prediction models. Based on the best prediction performance of ML algorithm, a prediction model is established, and the performance of the model is evaluated from three aspects: area under curve (AUC), sensitivity and specificity.

Results
In multivariate logistic regression analysis, T stage, PSA, Gleason score and bone metastasis were independent predictors of LNM in patients with intermediate- and high-risk PCa. By comprehensively comparing the prediction model performance of training set and test set, GBM model has the best prediction performance (F1 score = 0.838, AUROC = 0.804). Finally, we developed a preliminary calculator model that can quickly and accurately calculate the regional LNM in patients with intermediate- and high-risk PCa.

Conclusion
T stage, PSA, Gleason and bone metastasis were independent risk factors for predicting LNM in patients with intermediate- and high-risk PCa. The prediction model established in this study performs well; however, the GBM model is the best one.
Electrophysiological underpinnings of dysfunctional inhibitory control in adults with attention-deficit/hyperactivity disorder: evidence for reduced NoGo anteriorization
Authors: Papp Szilvia , Tombor László , Kakuszi Brigitta , Réthelyi János M. , Bitter István , Czobor Pál 
Published: May 2023

AbstractOur aim was to delineate the electrophysiological basis of dysfunctional inhibitory control of adult ADHD via investigating the anteriorization of the P3 component of the event-related brain response associated with the NoGo task condition (i.e., NoGo anteriorization, NGA). NGA is a neurophysiological measure of brain topography for cognitive response control, which indexes an overall shift of the brain’s electrical activity in anterior direction towards the prefrontal areas. While the NoGo P3 received considerable attention in the adult ADHD literature, the brain topography of this component, which reflects the inhibitory process, remains largely unaddressed. EEG recordings were obtained during a Go/NoGo task from 51 subjects (n = 26 adult patients with ADHD, n = 25 healthy controls) using a high-density, 128-channel BioSemi ActiveTwo recording system. ADHD patients had significantly lower P3 NGA response compared to controls. The decrease in NGA was related to impulsivity scores as measured by the Conners’ Adult ADHD Rating Scale: patients with higher impulsivity scores had significantly lower NGA. Treatment with stimulant medication, as compared to the lack of such treatment, was associated with a correction of the lower NGA response in ADHD patients. The current study revealed a lower NGA in adult ADHD, a finding which is consistent with the inhibitory control and frontal lobe dysfunctions described in the disorder. Our finding of the inverse relationship between NGA and impulsivity suggests that clinically more severe impulsivity is linked to a more pronounced frontal dysfunction in adult ADHD subjects.
A case of coexistent poorly differentiated adenosquamous carcinoma (glassy cell carcinoma), usual-type adenocarcinoma, and squamous cell carcinoma in situ of the cervix
Authors: Habara Kouki , Nishikori Asami , Kiyama Jin , Nakashima Manami , Koda Masanori , Sasaki Kenji , Sakashita Tomohisa , Tanaka Norifumi , Yonehara Shuji 
Published: May 2023

AbstractPoorly differentiated adenosquamous carcinoma (glassy cell carcinoma) of the cervix is extremely rare, accounting for 1–2% of all cervical cancers. Herein, we report a case with coexistent poorly differentiated adenosquamous carcinoma (glassy cell carcinoma), “usual-type” adenocarcinoma, and squamous cell carcinoma in situ of the cervix. A female patient in her 60 s was referred to our hospital and diagnosed with poorly differentiated adenosquamous carcinoma based on cervical cytology and biopsy. The tumor was classified as clinical stage IB1 cervical cancer following magnetic resonance imaging; radical hysterectomy was performed. Histopathological examination revealed poorly differentiated adenosquamous carcinoma (glassy cell carcinoma), usual-type adenocarcinoma, and squamous cell carcinoma in situ, all coexisting. All carcinoma regions showed identical sizes to high-risk human papillomavirus (HPV) in fragment analysis. The patient is currently alive, without evidence of recurrence, 31 months post surgery. In this case, three different carcinomas coexisted. Fragment analysis of the patient’s HPV status suggested that all carcinomas were related to an infection with the same high-risk HPV type. To determine the precise mechanism of tumor development, i.e., whether the tumors were of the mixed or collision type, further studies are needed, including clonal analysis for the loss of heterozygosity pattern.
The Impact of Convertase Subtilisin/Kexin Type 9 Monoclonal Antibodies with and without Apheresis on Platelet Aggregation in Familial Hypercholesterolemia
Authors: Konečný Lukáš , Hrubša Marcel , Karlíčková Jana , Carazo Alejandro , Javorská Lenka , Matoušová Kateřina , Krčmová Lenka Kujovská , Blaha Vladimír , Bláha Milan , Mladěnka Přemysl 
Published: May 2023

Abstract

Background and aims
It is well known that elevated cholesterol is associated with enhanced platelet aggregation and patients suffering from familial hypercholesterolemia (FH) have a high risk of thrombotic cardiovascular events. Although decreasing cholesterol level is associated with attenuation of platelet hyperactivity, there are currently no data on the effect of convertase subtilisin/kexin type 9 monoclonal antibodies (PCSK9ab) on platelet reactivity in FH. The aim of the study was to analyse the impact of different therapies including PCSK9ab on platelet aggregation in FH.

Methods
This study enrolled all 15 patients treated in the University Hospital Hradec Králové for FH. PCSK9ab have been administered in 12 of 15 patients while 8 patients were also undergoing lipid apheresis. Blood samples from all patients including pre- and post-apheresis period were tested for platelet aggregation triggered by 7 inducers, and the effect of 3 clinically used drugs (acetylsalicylic acid, ticagrelor and vorapaxar) was compared as well.

Results
Although apheresis decreased the reactivity of platelets in general, platelet responses were not different between non-apheresis patients treated with PCSK9ab and apheresis patients (post-apheresis values) with the exception of ristocetin. However, when compared to age-matched healthy population, FH patients had significantly lower platelet aggregation responses to 4 out of 7 used inducers and higher profit from 2 out of 3 used antiplatelet drugs even after exclusion of FH patients regularly receiving conventional antiplatelet treatment.

Conclusion
This study showed for the first time the suitability of PCSK9ab treatment for reduction of platelet reactivity in FH patients.
Parry response to Dialectical Anthropology forum on Classes of Labour
Authors: Parry Jonathan 
Published: May 2023

AbstractThe paragraphs that follow respond to some of the criticisms and comments that the contributors to this forum have made on my book. Many of these revolve around the central issue of social class and around my analysis of the manual blue-collar workforce of the central Indian steel town of Bhilai as sharply divided between two ‘classes of labour’ with separate and sometimes antagonistic interests. Some earlier commentaries on this argument had been sceptical, and many of the observations made here invoke much the same issues. In the first part of this response, I attempt to summarize my central argument about the class structure, the main criticisms of it, and my earlier attempts to answer these. The second part responds directly to the observations and comments made by those who have so generously
participated in the present discussion.
Isotopic niche of New Jersey terrapins suggests intraspecific resource partitioning, and little variability following a major hurricane
Authors: Denton Mathew J. , Hart Kristen M. , Wnek John , Moss Sarah A. , Avery Harold W. 
Published: May 2023

AbstractDiamondback terrapins (Malaclemys terrapin) are sexually dimorphic generalist turtles that inhabit salt marshes and estuaries along the Atlantic and Gulf coasts of the United States. On October 29th, 2012, Hurricane Sandy made landfall in New Jersey, USA, directly impacting terrapin populations inhabiting central and southern Barnegat Bay. To examine potential food web mediated impacts to the terrapin population and their foraging dynamics we examined carbon and nitrogen stable isotope values collected from terrapin tissues (2011, 2015, 2019) and resource taxa (2015, 2019) within Barnegat Bay. Isotopic analysis revealed that mature females had lower carbon and higher nitrogen values than immature females and males with almost no isotopic niche overlap, whereas males and immature females had statistically similar values with overlapping niches. Terrapins and resources collected from island habitats contained higher carbon and nitrogen values than those from mainland habitats, with little overlap in niche between habitats. There were no significant temporal variations detected in either carbon or nitrogen values from terrapins between years, or within each habitat pre- and post-Hurricane Sandy. These findings suggest long-term terrapin foraging dynamics have remained relatively stable, signifying resilience to disturbance events within the study site.
Prospects of Hybrid Conjugated Polymers Loaded Graphene in Electrochemical Energy Storage Applications
Authors: Adedoja Oluwaseye Samson , Sadiku Emmanuel Rotimi , Hamam Yskandar 
Published: May 2023

AbstractThe synergy between graphene and conducting polymers has the potential to revolutionize the energy storage sector to a more dependable, sustainable, and affordable energy source. Introducing graphene nanoparticles in the conductive polymers (polypyrrole and polythiophene) nanoparticles is a prospective technique to increase the charge transfer efficiency of the resulting nanocomposite. Subsequently, the fabrication method of graphene-polymer nanoelectrode is the most critical factor responsible for their excellent performance. This review presents a concise summary of graphene (Gr), polypyrrole (PPy), and polythiophene (PTh) synthesis techniques. The study revealed that the dispersion of nanoparticles could be controlled by suitable solvent, mixing approach, and drying conditions. In addition, the PPy/PTh/Gr nanocomposite is envisaged to be a promising nanoelectrode for sustainable and efficient energy storage capabilities. The future approaches to developing improved materials synthesis techniques for multi-applications (supercapacitors, sensors, and photovoltaic) are also provided.
Nonlinear dynamics and safety aspects of pressure relief valves
Authors: Kadar Fanni , Stepan Gabor 
Published: May 2023

AbstractDirect spring operated pressure relief valves are regular elements of high-pressure hydraulic systems; however, valve vibrations may still occur endangering the valve and the protected system. The damping of these vibrations is a crucial issue, whereas the external viscous damping at the valve cannot be increased boundlessly based on safety aspects. The vibrations emerge via Hopf bifurcations of either super- or subcritical type, and the nonlinear characteristics have an important role in the valve dynamics. Thorough nonlinear analysis is needed to guarantee safe operation. The linear stability analysis is extended by local and global bifurcation analysis to reveal the stable domains bounded by subcritical Hopf points and the possible bistabilities that exclude the safe operation. Afterwards, the effect of a downstream pipe is analysed, which can also carry safety risks based on the literature; however, the time delay originated in the wave propagation in the pipe may also have stabilising effects. The nonlinear analysis of the presented system compares analytical, semi-analytical and numerical results and assigns the safe parameter domains of the valve with respect to a wide range of relevant parameter variations.
3,4-Dioxygenated xanthones as antifouling additives for marine coatings: in silico studies, seawater solubility, degradability, leaching, and antifouling performance
Authors: Vilas-Boas Cátia , Silva Elisabete R. , Resende Diana , Pereira Beatriz , Sousa Gonçalo , Pinto Madalena , Almeida Joana R. , Correia-da-Silva Marta , Sousa Emília 
Published: May 2023

Abstract
Marine biofouling pollution is a process that impacts ecosystems and the global economy. On the other hand, traditional antifouling (AF) marine coatings release persistent and toxic biocides that accumulate in sediments and aquatic organisms. To understand the putative impact on marine ecosystems of recently described and patented AF xanthones (xanthones 1 and 2), able to inhibit mussel settlement without acting as biocides, several in silico environmental fate predictions (bioaccumulation, biodegradation, and soil absorption) were calculated in this work. Subsequently, a degradation assay using treated seawater at different temperatures and light exposures was conducted for a period of 2 months to calculate their half-life (DT50). Xanthone 2 was found to be non-persistent (DT50 < 60 days) at 50 μM, contrary to xanthone 1 (DT50 > 60 days). To evaluate the efficacy of both xanthones as AF agents, they were blended into four polymeric-based coating systems: polyurethane- and polydimethylsiloxane (PDMS)-based marine paints, as well as room-temperature-vulcanizing PDMS- and acrylic-based coatings. Despite their low water solubility, xanthones 1 and 2 demonstrated suitable leaching behaviors after 45 days. Overall, the generated xanthone-based coatings were able to decrease the attachment of the Mytilus galloprovincialis larvae after 40 h. This proof-of-concept and environmental impact evaluation will contribute to the search for truly environmental-friendly AF alternatives.
Environmental impact scenarios of organic fraction municipal solid waste treatment with Black Soldier Fly larvae based on a life cycle assessment
Authors: Ferronato Navarro , Paoli Riccardo , Romagnoli Francesco , Tettamanti Gianluca , Bruno Daniele , Torretta Vincenzo 
Published: May 2023

AbstractBiowaste treatment with Black Soldier Fly (BSF) larvae is an alternative option for organic waste valorization. Its environmental impacts should be assessed and compared with conventional treatment options. The research aims to evaluate the treatment of organic fraction of municipal solid waste (OFMSW) with BSF larvae through a life cycle assessment (LCA). This study employed data inventories from literature and aimed to provide a wide range of production parameter values to identify the potentialities of BSF treatment in the best-case and worst-case scenarios. The SimaPro9, the database Ecoinvent3.5, and the impact assessment method IMPACT 2002+ have been employed for the analysis. A sensitivity analysis of relevant parameters was conducted, considering the avoided impacts that can be obtained thanks to the exploitation of larvae proteins for bioplastics or fishmeal production. Research findings highlight six main environmental impact indicators: respiratory inorganics (kg PM2.5-eq), ozone layer depletion (kg CFC-11-eq), terrestrial ecotoxicity (kg TEG soil), land occupation (m2 organic arable), global warming (kg CO2-eq), and non-renewable energy (MJ primary). The most relevant process generating impacts is BSF breeding, followed by boiling, storage, and OFMSW treatment. The environmental performance is better when the conventional fishmeal substituted, thanks to BSF larvae production, is made from areas 10,000 km far, implementing a 100% renewable energy scenario, reducing the energy consumption by 50%, increasing the lifespan of the equipment to 15 years, and products are employed locally. The current study represents the first attempt to evaluate the global higher or lower environmental impact scenario related to OFMSW treatment through BSF larvae.
Graphical Abstract
The prevalence of anthropogenic nest materials differs between two distinct populations of migratory birds in Europe
Authors: Jagiello Zuzanna , Dylewski Łukasz , Aguirre José I. , Białas Joanna T. , Dylik Andrzej , López-García Alejandro , Kaługa Ireneusz , Olszewski Adam , Siekiera Joachim , Tobółka Marcin 
Published: May 2023

AbstractA major impact of human development is the transformation of natural habitats into farming lands and the expansion of built-up areas. Also, plastic pollution is affecting wildlife on a global scale. Discarded plastic is ubiquitous and accessible for birds, which can incorporate them into the nest structure. Here, we describe the differences in type, prevalence, and the amount of anthropogenic nest materials between two populations of terrestrial, mainly farmland bird, the white storkCiconia ciconia, on a broad geographical scale, from two migratory divides—eastern in Poland and western in Spain (in total 303 nests). In the two populations, we detected significant differences in the incorporation of anthropogenic nest material, as measured by the Human Footprint Index (HFI) and the Impervious Surface Areas (ISA). We found that ISA was positively related to anthropogenic nest material incorporation in the Spanish population, and HFI was positively related to anthropogenic nest material, in contrast to the Polish population, in which the relationships were not significant. Moreover, we showed that the prevalence of nests with anthropogenic nest material was two times higher in Spanish than in the Polish white stork population. This study demonstrates that the behavior of incorporation of the anthropogenic nest material differs between two distinct populations of a single bird species.
Hybrid system coupling ozonation and nanofiltration with functionalized catalytic ceramic membrane for ibuprofen removal
Authors: Szymański Kacper , Mozia Sylwia , Ayral Andre , Brosillon Stephan , Mendret Julie 
Published: May 2023

Abstract
The investigations on the removal of ibuprofen (IBU) in a hybrid system coupling ozonation and nanofiltration with functionalized catalytic ceramic membrane are presented. The gaseous ozone into feed water in concentration of 11 g Nm−3 was supplied. Positive influence of catalytic ozonation on ibuprofen decomposition was observed. The application of catalytic nanofiltration membrane led to the ibuprofen removal of 91% after the first 15 min from the beginning of the O3/NF process, while at the same time, for the pristine membrane, it was equal to 76%. The investigations revealed incomplete degradation of drug under pH 3 after 2 h, i.e., 89%. On the other hand, the addition of inorganic salts did not affect the catalytic ibuprofen removal efficiency. Under acidic pH, the highest permeate flux decline (26%) was noted, whereas no differences between permeate flux measured under natural and alkaline conditions were observed. During the treatment process, three IBU by-products were detected, which significantly affected the permeate toxicity; however, after 2 h of catalytic nanofiltration, the product of treatment process was found as non-toxic.
Screw Extrusion Additive Manufacturing of Carbon Fiber Reinforced PA6 Tools
Authors: Barera G. , Dul S. , Pegoretti A. 
Published: May 2023

AbstractThe creation of tools by additive manufacturing is becoming increasingly convenient for CFRP one-off and small batch production. Screw extrusion additive manufacturing of thermoplastic polymers has boosted the development of large format manufacturing solutions. Interlayer adhesion and anisotropic properties of a 3D printed part are indisputably key aspects of tool manufacturing process. In this study, thermal and mechanical properties of large format 40% carbon fiber reinforced polyamide 6 3D printed tools were determined. Moreover, the influence on part performance of two main printing parameters, deposition temperature and extruding pressure, was analyzed with respect to polymer melt rheology. The printed material revealed a highly anisotropic thermal and mechanical behavior associated with the alignment of the high carbon fiber content. The optimal process window was identified in terms of substrate deposition temperature. Along the print direction, no major impact on tensile and flexural mechanical properties was detected, while the injection molding values were exceeded by approximately 10%. The layer adhesion was estimated by measuring the stress at break on transversely Z-oriented specimens. Higher deposition temperatures and pressures, combined with lower viscosity, promote wetting and bond formation between layers, ultimately leading to more consistent performances. The best results in the transverse direction were achieved between 140 and 160 °C, reaching roughly a fifth of the longitudinal values. A significant drop in performance was detected below 120 °C, which was identified as the minimum process temperature. A post-process annealing heat treatment was also investigated, no beneficial outcomes were reported.