bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Talent Management, Work-Life Balance, Hrm Practices Terhadap Job Satisfaction Pada Flight Attendants Maskapai Penerbangan Indonesia
Authors: Cahyani Riska Putri , Netania Emilisa  
Published: May 2023

Tujuan dari penelitian ini adalah menganalisis pengaruh Talent Management, Work-Life Balance, HRM practices terhadap Job Satisfaction pada flight attendants maskapai penerbangan Indonesia. Variabel independen dalam penelitian ini adalah Talent Management, Work-Life Balance, HRM practices dan variabel dependen dalam penelitian ini adalah Job Satisfaction. Data dikumpulkan dari 160 responden yaitu menyebarkan kuesioner melalui g-form yang diisi oleh flight attendants maskapai penerbangan Indonesia. Teknik pengolahan data yang digunakan pada penelitian ini yakni pengujian instrument seperti uji validitas dan realibitas serta Structural Equation Modeling (SEM) menggunakan SPSS dan AMOS. Hasil pengujian hipotesis dalam penelitian ini menunjukkan terdapat pengaruh positif antara Talent Management terhadap Job Satisfaction, Work-Life Balance berpengaruh positif terhadap Job Satisfaction, dan HRM Practices berpengaruh positif terhadap Job Satisfaction. Implikasi bagi perusahaan maskapai penerbangan di Indonesia adalah untuk meningkatkan Job Satisfaction pada flight attendants melalui Talent Management dan HRM Practices yang diberikan oleh perusahaan agar flight attendants dapat menyesuaikan Work-Life Balance dalam menjalankan pekerjaannya.
The Emerging Role of microRNAs as Novel Diagnostic and Therapeutic Tools For Breast Cancer: a systematic review
Authors: Mumtaz Sara , Saeed Rida Fatima , Qazi Asma Saleem , Akhtar Nosheen , Awan Uzma Azeem 
Published: May 2023

Objective: A systematic review was conducted to evaluate recent studies performed on miRNAs as a diagnostic and therapeutic biomarker in breast cancer.Study Design: Online standard databases like PubMed, EMBASE, Web of Science and COCHRANE library were searched to identify research articles relavant to the topic. Place and Duration of Study: All online published studies between 2010-2020, in the scientific electronic databases were analyzed.Materials and Methods: This review was performed according to PRISMA guidelines. Databases were systematically analyzed to explore the diagnostic and therapeutic potentials of miRNAs in breast cancer.Results: We identified twenty-seven studies after literature search. We found six studies focused on diagnosis, sixteen on therapeutics and five on both diagnosis and therapeutics of miRNAs in breast cancer.Conclusion: The combined data obtained in the present systematic review specify that miRNAs could serve as novel diagnostic and therapeutic biomarkers in breast cancer, whereas the practical relevance of the current results has yet to be established.
Incidence of Surgical Glove Perforations during Surgical Procedures at a Tertiary Care Hospital, Islamabad
Authors: Idrees Hina , Rashid Isbah , Aqib Muhammad , Shah Sajid Ali , Ali Sana Sharafat , Ahsan Muhammad Faheem , Waqar S H 
Published: May 2023

Objective: To determine the rate and patterns of surgical glove perforation during surgical procedures and to compare the rates between emergency and elective surgeries at PIMS, Islamabad.Study Design: A cross-sectional study.Place and Duration of Study: The study was conducted in the Department of General Surgery of Pakistan Institute of Medical Sciences (PIMS), Islamabad, Pakistan from January 2021 to June 2021.Materials and Methods: Surgical gloves are worn in various major surgeries, elective and emergency, and were studied post-procedure, for six months’ period. Gloves were examined by standardized visual and hydro-insufflation techniques to check for perforations. Glove quality was also noted. The type of procedure carried out, the number of perforations, the location of perforations, and the roles of the surgical team were all recorded along with other relevant information. Data were analyzed using SPSS version 22.Results: A total of 120 gloves were tested perforated, 69/100 for elective and 51/80 for emergency procedures. Perforations in emergency procedures were 57.5% ±0.44, while 42.5% ±0.52 in elective surgeries. Glove perforations were extremely common among first assistants (26.67%) and second assistants (9.17%) during emergency surgeries as well as among first surgeons (30%) and scrub nurses (11.67%) during elective procedures. Only 1.2% of inner glove perforations were recorded. The most commonly perforated parts of the glove were the left hand, the left index finger and the thumb. Residents had a lower rate of glove perforation than consultant surgeons.Conclusion: Calculated perforation rate is high, posing a clear threat to the surgical workforce. Preventive measures such as double gloving should be routinely adopted for all surgical procedures. Glove quality is also an important contributing element.
Epidemiological Characteristics, Spectrum of Upper Gastrointestinal Tract Injuries and Burden of Corrosive Intake Patients in A Tertiary Care Hospital in Islamabad
Authors: Abbasi Hyder Wajid , Aftab Warda , Shahid Sara , Ali Mashood , Zahid Javeria , Naz Shumaila , Ishtiaq Amna 
Published: May 2023

Objective: To investigate the epidemiology and spectrum of upper gastrointestinal (UGI) tract injuries, as well as to assess the burden of Corrosive intake patients who presented to an Islamabad tertiary care hospital.Study Design: Descriptive cross-sectional.Place and Duration of Study: The study was carried out at the Department of Gastroenterology of Pakistan Institute of Medical Sciences, Islamabad, Pakistan from January 2021 to December 2021.Materials and Methods: A retrospective descriptive study was carried out at the department of Gastroenterology using patient records. After taking a thorough history, patients were admitted in the hospital, which was followed by a physical examination, necessary investigations, and an initial emergency management. The study did not include any follow-up cases. Corrosive ingestion induced tissue damage was assessed via endoscopy using Zargar’s classification. The data was analyzed using SPSS version 26.Results: The total number of patients who were brought to emergency department with corrosive ingestion during one year were 74. There were 45 females (60.81%) and 29 male patients (39.19%). Age ranged from 13 to 60 years (mean 27.01 ± 18.91) with highest incidence in the age group of 21-30 years which was 44.59 % followed by 11-20 age Group (28.28 %). 41 patients were unmarried (55.41%), whereas 33 were married (44.59 %). Corrosive ingestion was most common in illiterate patients (44.59 %). 46 patients (62.16%) confessed that they ingested corrosive substance intentionally while 28 (37.84 %) claimed it happened due to accidental ingestion. Washroom cleaner was found to be the most commonly used corrosive Agent (90.54%). The most common sites that sustained corrosive injuries were the oropharynx and oesophagus, while the duodenum was found to be the least affected with normal endoscopic examination in the majority of the patients (51.35 %).Conclusion: In developing countries, corrosive ingestion is a major public health concern, with a high proportion of suicidal ingestions. It is particularly common in suicidal young people with easy access to washroom cleaners. The seriousness of this problem emphasises the importance of pursuing multidisciplinary solutions. In addition, strict action and stringent legislation by governing bodies are required in developing countries to limit adults' unrestricted access to hazardous corrosive elements.
Evaluation of Risk Factors Associated with Positive Exercise Tolerance Test
Authors: Ramzan Muhammad , Shahid Muhammad , Zohaib Zahoor Muhammad , Shahzad Amir , Razzaq Abdul , Ali Hashmi Kashif 
Published: May 2023

Objective: To determine the potential risk factors in patients aged under 40 years with a positive Exercise Tolerance Test (ETT).Study Design: Prospective study.Place and Duration of Study: The study was carried out at the Department of Cardiology Choudhary Pervaiz Elahi Institute of Cardiology (CPEIC), Multan, Pakistan, from 1st January 2021 to 1st March 2022.Materials and Methods: The study included 285 patients with positive ETT, selected through non-probability consecutive sampling. Patients were grouped into two age brackets: 20-30 and 31-40. Patients were advised to stop taking nitrates, calcium channel blockers and beta blockers a day before the test. The patients were investigated for potential risk factors that caused the positivity of EET.Results: The study was conducted on 285 patients. The age of the participants was 30.12±5.64 years. There were 185 (64.9%) males and 100 (35.1%) females. The BMI was .32±1.38 kg/m2. Obesity was recorded in 38 (13.3%) patients, 85 (29.8%) had a family history, 63 (22.1%) had dyslipidemia, hypertension in 58 (20.4%), 32 (11.2%) had a smoking history, and 56 (19.6%) had diabetes mellitus. Diabetes Mellitus (p=0.00) and dyslipidemia (p=0.004) were found to be the most significant risk factors in patients aged between 31-40 years with positive EET.Conclusion: Diabetes mellitus and dyslipidemia are the most significant causes of positive EET in patients aged between 31-40 years.
Investigation on Production of Edible Oil from Rice Husk
Authors: A Murugesan , K Balamurugan , Gowthaman  , R Mohammed shabeer , R Abishek 
Published: May 2023

Rice husk, the hard protective covering of the grain of rice (paddy), is a massive agricultural residue. Rice bran oil (RBO) also called wonder oil is well known for its numerous health benefits. The presence of a unique antioxidant called oryzanol contributes maximum antioxidant activity to rice bran oil. Rice bran oil has number of advantages over the other edible oil. The results showed that the rice bran has 21.44% of raw oil, with a chemical composition (based on fatty acids) of 48.48% oleic acid, 35.26% linoleic acid, and 14.54% palmitic acid, as well as a free fatty acid content of 8.15%. The oil contains vitamins such as B and E, proteins, fatty acids, antioxidants, collagen, elastin, oryzanol and ferulic acid. Antioxidants and Vitamin E are good for the heart as they reduce the amount of bad cholesterol and prevent cardiac arrest. Compounds such as oryzanol and ferulic acid are used as functional food supply ingredients. Apart from these benefits, the consumption of rice bran oil maintains the immune system, aids in weight loss, prevents diseases like cancer, relieves symptoms of menopause and enhances skin health. These advantages motivate capitalists to venture into rice bran oil manufacturing and thus can supply cooking oil and various other essential products that require rice bran oil as a component of it. Is. Although it is classified as an “oil”, rice bran oil is completely safe for consumption by patients with heart problems, diabetes, cholesterol, or high blood pressure. Because of all these benefits, you can expect good profits in the Rice Bran Oil Making Business.
digitala arbetslivet
Authors: Hansson Kristofer 
Published: May 2023

The virtual workplace
This article examines what the digitalization of healthcare has come to mean for nurses as a professional group. Digitalization is understood in the article as a term that is concerned with everything from digital surveillance systems that partially take over the nurses’ attentive observation of their patients, to healthcare meetings that do not take place in the hospital but transpire with the help of cameras and monitors. Another dimension of digitalization is that which goes beyond healthcare meetings and concerns digital journal systems and how they change working life from writing on paper by hand to having all the care of the patient visible on a computer screen. The purpose of the article is therefore to culturally analyse and examine how the working life of nurses change when healthcare and medical care are digitized. What happens when digital technology enters the profession and when working nurses have to spend an increasing amount of time in a liaison with / association with the virtual environment?
Four nurses, aged 46 years and over were interviewed based on a questionnaire with open questions. Based on the interviews, this article presents four key themes, namely (1) the actual digitalization of health and medical care and how it affects the nurses; (2) patients who via the Internet can be more apprised of their illness and treatment options and thus can also affect healthcare meetings in new ways, (3) the different contexts of digital technologies that are at risk of collapsing into each other and allowing the patient's private attitude/approach to come to the attention of the nurses, and (4) how the boundary between working life and leisure time is affected by the new technology.
Digital technology thus creates various mediated platforms that transform the interactions in, for example, a healthcare meeting. These interactions can occur both in the virtual world as well as in face-to-face relationships in a healthcare meeting. It has been central to the article's argumentation to reveal how the impact can go both ways and that this fact affects nurses working life in new and unexpected ways. Based on this reasoning, the article also argues for ethnological work life research that focuses much more on the complexity that working individuals meet, both in their profession and in spare time. There is not always a clear boundary between these two worlds. If anything, ethnological research into working life has highlighted the importance of focusing on the entire life situation of the workforce; this is something which it is even more central to make evident in relation to the digitalized working life.
Percepción de los maestros de Educación General Básica sobre el Trastorno por Déficit de Atención e Hiperactividad en Niños
Authors: Samaniego Luna Natasha Ivanova , Chamba Carchi Yosselyn Nathaly , González Estella José Eduardo 
Published: May 2023

Este estudio analiza la formación académica de los maestros de educación general básica (EGB) y su relación con el nivel de conocimientos acerca del TDAH en niños. La muestra incluyó a 342 maestros de los diferentes centros educativos del Distrito 11D01- Loja; 19,3% (n= 66) hombres y 80,7% (n= 276) mujeres; cuyas edades fluctuaron entre 20 a 65 años, formados en tercero y cuarto nivel de educación, en quienes se aplicó el test (Knowlegde of Attention Deficit Hyperactivity Disorder Scale) KADDS, observándose que aquellos con cuarto nivel y capacitación acerca del trastorno, a través de educación formal (pregrado y posgrado), así como no formal (charlas y conferencias), mostraron conocimiento alto (58% n=95) principalmente en las subescalas síntomas y diagnóstico, además de tratamiento, en relación a los maestros que tuvieron formación hasta de tercer nivel. La prueba estadística chi cuadrado, determinó asociación significativa entre formación académica, nivel de conocimiento y estrategias utilizadas por el maestro para alcanzarlo. Los resultados sugieren, es necesario que los maestros incrementen sus conocimientos sobre el TDAH. Mejorar la formación y capacitación en los maestros, podría repercutir en la calidad y cantidad de conocimientos sobre este trastorno.
Identificación de Hipoplasia Cerebelar en gestante de 35,6 semanas, a propósito de un caso
Authors: Silva Gutiérrez Paola Alejandra , Cajas Lema Carlos Luis , Sola Villalva María Victoria , Silva Poaquiza Violeta Alexandra , Zambrano Zambrano Michelle Lissette 
Published: May 2023

La hipoplasia cerebelar se asocia a una amplia variedad de características neuro-radiológicas, lo cual representa un gran desafío para los médicos que identifican estos casos, principalmente en etapa prenatal.
Objetivo. Describir un caso clínico de hipoplasia cerebelar identificado en periodo prenatal y analizar el protocolo de atención aplicado en el primer nivel de salud para embarazadas de alto riesgo.
Material y métodos. Estudio descriptivo y retrospectivo, presentación de caso clínico.
Resultados. Se presenta un caso clínico de una paciente femenina de 43 años, gestante de 35,6 semanas, sin antecedentes de importancia, que acude a primer nivel de atención por su cuarto control prenatal, asintomática, Score mama de cero puntos, se evidencian obesidad grado 1, al examen físico paciente gestante, activa, afebril, cabeza y órganos de los sentidos sin patología aparente, cardiopulmonar normal, abdomen útero gestante, altura uterina 32cm, FCF 149 lpm, feto único pelviano, región inguinogenital no se evidencia sangrado ni secreción vaginal. Además, presenta ecografía del tercer trimestre con hallazgos morfológicos patológicos de Hipoplasia de cerebelo, es referida a segundo nivel de atención para seguimiento y elección de tratamiento acorde al caso.
Conclusión. La atención brindada sigue parámetros de captación y manejo de las embarazadas de alto riesgo según las guías del ministerio de salud, sin embargo, es importante que las pacientes decidan cumplir con las recomendaciones de los médicos en primer nivel, para evitar complicaciones a futuro.
La tecnocultura digital en la enseñanza-aprendizaje
Authors: Morales Cordero Carlos Andrés , Viloria Espitia Jairo Miguel 
Published: May 2023

En el presente artículo resulta de gran utilidad determinar la incidencia que ejerce la Tecnocultura digital en la educación cuando es parte de las herramientas de que se valen los educadores para realizar su trabajo. Dicha incidencia se estudia, para el caso de la presente investigación, caracterizado por la globalización que ha involucrado a todas o casi todas las comunidades humanas en un mismo momento de la historia universal, posibilitado este fenómeno histórico ante todo por el inusitado desarrollo de las tecnologías informáticas, al punto de que los más recientes inventos casi inmediatamente recorren todo el planeta; lo que permite que desde la más grande metrópoli hasta la aldea más apartada conozcan en cuestión de días los últimos inventos, lo que actualmente se llama sociedad del conocimiento y cómo su evolución, producto de la tecnología, ha abarcado distintas áreas, permitiendo innovar en la educación, estimulando la creación de nuevos conocimientos, de esta manera se describe la importancia de cada agente educativo (docente-alumno) y su rol transformador en el proceso de enseñanza-aprendizaje.
The Behavior of Bp He-strong Stars in the far UV—Paper I: HD 37776
Authors: Monier Richard 
Published: May 2023

Abstract
The analysis of thirty-two spectra of the Bp He-strong variable star HD 37776 recorded by the SWP camera on board the International Ultraviolet Explorer reveals variations of the far-ultraviolet spectral energy distribution over a time interval of about 26 hr. Variations are present shortwards of 1450 Å which can be partly attributed to variations of lines and continuum of Si ii. Other lines due to C ii, Si iii and Si iv also contribute to the opacity in this range too. The variations suggest that silicon and possibly carbon are not distributed in a uniform manner over the surface.
Subcellular Translocation of Yorkie through the PRP4K–CRM1 Axis Regulates Antimicrobial Peptides Transcription and Defense against Bacterial Infection in Crab
Authors: Qin Yukai , Zhao Ke , Zhou Kaimin , Luo Zhi , Nan Xingyu , Wang Qun , Li Weiwei 
Published: May 2023

Abstract
The Hippo signaling pathway plays important roles in innate immunity. In the current study, we found that bacterial infection did not influence mRNA and protein levels of yorkie (Yki), which is an important terminal molecule of the Hippo signaling pathway. However, bacterial infection promoted the translocation of Yki from the nucleus to the cytoplasm in Chinese mitten crab (Eriocheir sinensis), thus attenuating Yki-suppressed transcription of antimicrobial peptides through Cactus. Chromosome region maintenance 1 (CRM1)–silenced crab hemocytes significantly suppressed Yki translocation from the nucleus to the cytoplasm upon bacterial infection, resulting in significantly increased expression of Cactus, decreased expression of antimicrobial peptides, and higher bacterial susceptibility, which demonstrated the regulatory role of CRM1 in subcellular localization of Yki. However, RNA interference of Scalloped (Sd) exhibited no effect on the subcellular localization of Yki and its regulation of Cactus/antimicrobial peptides. Moreover, we elucidated that both CRM1 and Sd could interact with Yki and that the PRP4K-mediated phosphorylation of a conserved serine amino acid residue in the nuclear export signal of Yki is essential for interaction between Yki and CRM1; however, the phosphorylation did not affect the binding of Yki with Sd. We also found that bacterial infection significantly promoted the expression of PRP4K in hemocytes; RNA interference of PRP4K and phosphatase inhibitor suppressed Yki translocation from the nucleus to the cytoplasm, promoting Cactus expression and inhibiting antimicrobial peptide expression. Thus, subcellular localization of Yki regulates antibacterial infection through both PRP4K and CRM1 in crabs.
METTL3-Mediated m6A Modification of TRIF and MyD88 mRNAs Suppresses Innate Immunity in Teleost Fish, Miichthys miiuy
Authors: Geng Shang , Zheng Weiwei , Zhao Yan , Xu Tianjun 
Published: May 2023

Abstract
Methyltransferase (METTL3), the most important N6-methyladenosine (m6A) writer, plays a vital role in regulating immune-related signaling pathways. However, the underlying mechanism of METTL3 action remains largely unknown, especially in lower vertebrates. The results of this study show that METTL3 inhibits innate immune response and promotes the infection of miiuy croaker, Miichthys miiuy, by Siniperca chuatsi rhabdovirus and Vibrio anguillarum. Significantly, the function of METTL3 in inhibiting immunity depends on its methylase activity. Mechanistically, METTL3 increases the methylation level of trif and myd88 mRNA, rendering them sensitive to degradation by the YTHDF2/3 reader proteins. By contrast, we found that the YTHDF1 reader protein promotes the translation of myd88 mRNA. In summary, these results indicate that METTL3-mediated m6A modification of trif and myd88 mRNAs suppresses innate immunity by inhibiting the TLR pathway, unveiling a molecular mechanism by which RNA methylation controls innate immunity to pathogens in the teleost fish.
<b>RETRACTION</b>: Intrinsic innervation and dopaminergic markers after experimental denervation in rat thymus
Authors: Mignini Fiorenzo , Sabbatini Maurizio , D'Andrea Vito , Cavallotti Carlo 
Published: May 2023

On behalf of the coauthors and with much regret, I must retract our publication entitled “Intrinsic innervation and dopaminergic markers after experimental denervation in rat thymus” published in European Journal of Histochemistry 2010;54(2):e17 for the following reason:
Unfortunately, now, after thirteen years, we have realized that some microphotographs published in the paper have been processed to improve the presentation of the images. The three surviving authors of the paper agree that the processing of the presentation images is against the COPE Ethical Editorial Standard, although the presentation images do not alter the integrity of methodological procedures and the results of the research work, obtained from the direct analysis of slides under microscope and rigorous statistical analysis of data; therefore, we, the authors of the above indicated paper, request the retraction of the publication.
We apologize for what happened.

Maurizio SabbatiniDip. di Scienze e Innovazione Tecnologica (DISIT)Università del Piemonte OrientaleAlessandria, Italy