bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integrated Case Presentation Seminar: Bridging Parallel Fields to Improve Psychiatry and Psychology Learner Experience
Authors: Leffler Jarrod M. , Romanowicz Magdalena , Brennan Elle , Elmaghraby Rana , Caflisch Sara , Lange Hadley , Kirtley Alexander T. 
Published: December 2022

Abstract
Daily clinical practice of mental health professionals often requires interaction between providers from diverse training and professional backgrounds. Efforts to engage mental health trainees across disciplines are necessary and have had varied outcomes. The current study reviews the development and implementation of a monthly one-hour integrated case presentation seminar (ICPS) as part of independent psychology and psychiatry two-year fellowships at a Midwestern teaching hospital. The training integrated a semi-structured seminar to facilitate case presentation within a group setting. The focus of the seminar was to allow for exposure to conceptualization, diagnostic, and treatment strategies and skills, as well as science-based practice techniques for trainees. Learner survey results and the sustained offering of the seminar suggest the format and goals of the seminar are feasible and acceptable. Based on the current preliminary findings, similar training programs may find benefit in strategies to enhance integrated training opportunities for psychiatry and psychology trainees.
Investigating the effectiveness of the supportive-educational program, based on COPE model, on the quality of life and caregiver burden of family caregivers of heart failure patients: A randomized clinical trial study
Authors: Alaei Atefeh , Babaei Sima , Farzi Sedigheh , hadian Zahra 
Published: December 2022

Abstract
Background: Heart failure (HF) is one of the common and spreading diseases in the world, especially in developing countries. As HF symptoms progress, the need for care by the family increases in these people, so that it affects the quality of life and the caregiver burden of the family. The aim of the present study was to determine the effectiveness of the supportive-educational program, based on COPE care model, on the quality of life and caregiver burden of family caregivers of HF patients.
Method: This clinical trial was conducted on 90 caregivers of HF patients admitted to Chamran Hospital of Isfahan in 2021. Patients were selected using convenience sampling method and were divided into experimental (n=45 people) and control (n=45 people) groups based on random allocation (card method). The experimental group received problem-solving skills based on the four components of the COPE model (creativity, optimism, planning and expert advice) in six sessions during one month. In order to collect data, the 36-Item Short Form Survey (SF-36) and the Zarit Burden Interview (ZBI) were used in two groups before, after and three months after the intervention.
Results: There was a significant difference between the experimental and control groups in terms of gender (p<0.05), which was considered as a confounding factor. This confounding factor had no significant effect on the two components of quality of life and caregiver burden (p>0.05). There was a significant difference between the two groups in terms of mean scores of quality of life and care burden, immediately (75.99, 16.60) and three months after the intervention, respectively (78.78, 12.73) (p<0.05).
Conclusions: The results of the present study showed that the COPE model plays a significant role in increasing the quality of life and reducing the caregiver burden of caregivers of HF patients.
Trial registration: This study is registered by Iranian Registry of Clinical Trials with decree code: IRCT20211128053202N1on 2022-02-20.
Effects of epidural analgesia on gastric emptying in parturients monitored by ultrasound
Authors: Wu Wei , Bu Wenhao , Chen Lin , Yan rongrong , wan shengjun 
Published: December 2022

Abstract
Background:
Using B-ultrasound monitoring, we compared gastric emptying of semi-solid food between parturient women undergoing versus not undergoing epidural analgesia.
Methods
Eighty-six full-term, low-risk parturients were selected and divided into two groups according to epidural analgesia status: epidural analgesia group (LA, n = 66) and non-epidural analgesia group (NA, n = 20). The cross-sectional area of the gastric antrum (CSA0) was measured while fasting using B-ultrasound, and the time recorded as T0. The parturients in both groups then ate about 300 g millet congee (about 600 KJ). The CSAs of the gastric antra were measured by ultrasonography 60, 90, and 120 minutes after the experimental meal, these areas being recorded as CSA1, CSA2 and CSA3 and the corresponding time points as T1, T2, and T3. Pain scores of parturients at these four time points were recorded.
Results
CSA1, CSA2, and CSA3 were larger in the NA than in the LA group, and the gastric emptying time was longer in the NA than in the LA group (P < 0.05). Pain scores were higher in the NA than LA group at the three time points of T1, T2, T3 (P < 0.05).
Conclusions
Gastric emptying was faster in parturient women who undergo epidural analgesia than those who not. Pregnant women can safely eat small amounts of semi-solid food to meet their energy needs during delivery.
Braille Recognition by E-skin System based on Binary Memristive neural network
Authors: Liu Y. H. , Wang J. J. , Wang H. Z. , Liu S. , Wu Y. C. , Hu S. G. , Yu Q. , Liu Z. , Chen T. P. , Yin Y. , Liu Y. 
Published: December 2022

Abstract
Braille system is world widely used for visually impaired people for communication. However, there are still some visually impaired people who are not able to learn Braille system due to various factors, such as the age (too young or too old), damage of brain, etc. A wearable and low-cost Braille recognition system may substantially help these people recognize Braille or assist them in Braille learning. In this work, we fabricated polydimethylsiloxane (PDMS)-based flexible pressure sensors to construct an electronic skin (E-skin) for the application of Braille recognition. The E-skin mimics the human touch sensing function for collecting Braille information. The Braille recognition is realized with a neural network based on memristors. We utilize a binary neural network algorithm with only two bias layers and three fully connected layers. Such neural network design remarkably reduces the calculation burden and thus the system cost. Experiments show that the system can achieve a recognition accuracy of up to 91.25%. This work demonstrates the possibility to realize a wearable and low-cost Braille recognition system and a Braille learning-assistance system.
Piloting an ICU follow-up clinic to improve health-related quality of life in ICU survivors after a prolonged intensive care stay (PINA): Feasibility of a pragmatic randomised controlled trial
Authors: Drewitz Karl Philipp , Hasenpusch Claudia , Bernardi Christine , Brandstetter Susanne , Fisser Christoph , Pielmeier Katharina , Rohr Magdalena , Brunnthaler Vreni , Schmidt Konrad , Malfertheiner Maximilian , Apfelbacher Christian 
Published: December 2022

Abstract
Background
ICU survivors often suffer from prolonged physical and mental impairments resulting in the so called “Post-Intensive Care Syndrome” (PICS). The aftercare of former ICU patients affected by PICS in particular has not been addressed sufficiently in Germany so far. The aim of this study was to evaluate the feasibility of a pragmatic randomized trial (RCT) comparing an intensive care unit (ICU) follow-up clinic intervention to usual care.
Methods
This pilot study in a German university hospital evaluated the feasibility of a pragmatic RCT. Patients were assigned in a 1:1 ratio to an ICU follow-up clinic intervention or to usual care. The concept of this follow-up clinic was previously developed in a participatory process with patients, relatives, health professionals and researchers. We performed a process evaluation and determined acceptability, fidelity, completeness of measurement instruments and practicality as feasibility outcomes. The RCT’s primary outcome (health-related quality of life) was assessed six months after ICU discharge by means of the physical component scale of the Short-Form-12 self-report questionnaire.
Results
Principal findings related to feasibility were 85% consent rate (N = 48), 34% attrition rate (N = 41) and 77% completeness of outcome measurements. 41 participants (15 women, median age 60 years) were included of whom 66% completed the study (12/21 in the intervention group, 15/20 in the control group). Median length of ICU stay was 13 days and 85% (N = 41) received mechanical ventilation, median Sequential Organ Failure Assessment Score was nine. 62% of the intervention group (N = 21) fully completed all components of the intervention (fidelity). Six-month follow-up assessment was planned for all study participants and performed after 197 days (median). The primary effectiveness outcome (health-related quality of life) could be measured in 93% of participants who completed the study (N = 27).
Conclusion
The participatory developed intervention of an ICU follow-up clinic and the pilot RCT both seem to be feasible. We recommend to start the pragmatic RCT on the effectiveness of the ICU follow-up clinic.
Trial registration
ClinicalTrials.gov US NLM, NCT04186468, Submission: 02/12/2019, Registration: 04/12/2019, https://clinicaltrials.gov/ct2/show/NCT04186468
Moya-Moya like vasculitis secondary to sarcoidosis: a rare case report of concomitant ischemic infracts and sub-arachnoid hemorrhage
Authors: Zouari Rania , Saeid Mohamed Zakaria , Sassi Samia Ben 
Published: December 2022

Abstract
Background : Sarcoidosis is a rare idiopathic systemic inflammatory disease that mainly affects the lymph nodes, lungs, skin and eyes. Nervous system involvement is only seen in 5% of cases of sarcoidosis. Cerebral vasculitis, is particularly uncommon in patients with sarcoidosis, with serious outcome.
Case presentation : We reported the case of a 55 years-old female who developed a severe hemicranial headache with nausea and vomiting. She had a history of erythema nodosum. The clinical examination showed left arm weakness and central facial paralysis, along with brisk tendon reflexes and arthralgia. Brain MRI showed a moderate subarachnoid hemorrhage, multiple acute lacunar infracts, and a large ischemic stroke over the right superficial sylvian territory; and MR angiography revealed a Moya-Moya like vasculopathy pattern and the occlusion of intracranial internal carotid arteries. Extensive laboratory workup including infectious serologies and vasculitis screen was negative; and Angiotensin-converting enzyme levels were normal. Findings in the CT chest and abdomen scan, and Broncho alveolar lavage confirmed the diagnosis of sarcoidosis.
Conclusions : Cerebrovascular manifestation are uncommon in sarcoidosis. Multiple factors seem to be involved in the pathogenesis of sarcoidosis related vasculopathy. The diagnosis should be considered when recurrent infracts and hemorrhage are encountered in a patient having systemic symptoms of sarcoidosis.
A novel c.64G&gt;T (p.G22C) NR5A1 mutation in a Chinese adolescent with 46, XY disorders of sex development: a case report
Authors: Zhang Dan , Wang Dajia , Tong Yajie , Li Mingyu , Meng Lingzhe , Song Qiutong , Xin Ying 
Published: December 2022

Abstract
Background
Adolescents with 46, XY disorders of sex development (DSD) face additional medical and psychological challenges. To optimize management and minimize hazards, correct and early clinical and molecular diagnosis is necessary.
Case presentation:
We report a 13-year-old Chinese adolescent with absent Müllerian derivatives and suspected testis in the inguinal area. History, examinations, and investigations were available for clinical diagnosis, and subsequent genetic sequencing was employed for molecular diagnosis. We identified a novel variation in nuclear receptor subfamily 5 group A member 1 (NR5A1) [c.64G > T (p.G22C)] in the patient. In vitro functional analyses of the novel variant suggested no impairment to NR5A1 mRNA or protein expression relative to wild-type, and immunofluorescence confirmed similar localization of the NR5A1 mutant to the cell nucleus. However, we observed decreased DNA-binding affinity by the NR5A1 variant, while dual-luciferase reporter assays showed that the mutant effectively downregulated the transactivation capacity of anti-Müllerian hormone. We described a novel NR5A1 variant and demonstrated its adverse effects on the functional integrity of the NR5A1 protein resulting in serious impairment of its modulation of gonadal development.
Conclusions
This study provides deeper insights into the NR5A1 mutational spectrum.
Role of trombe walls on the reduction of energy load and sustainable development in an eco-resort residential building in Binalood region with a cold and dry climate
Authors: Sady Hamed , Rashidi Saman , Rafee Roohollah 
Published: December 2022

Abstract
Trombe wall is a passive strategy that reduces the energy consumption in buildings and helps for sustainable development of residential sector. Applying these walls is very important in areas that need heating load in winter. In this study, a set of trombe walls is evaluated for the energy management of a residential building under real conditions in Binalood region with a cold and dry climate. In order to study the potentials of trombe wall, four different designs, including C, T3SG, T4SG and T designs, for trombe walls are considered. Trombe walls of all four suggested designs are exposed to outdoor conditions and installed at 17 places on the southern walls of the residential building. The occupied surface by these walls is 60% of the total area of the southern walls. Therefore, using the southern natural light is possible for all 17 places. The obtained results show that when the shade (Blinds) and ventilation values are considered on the common wall with specific seasonal and daily functions, the use of trombe walls in all designs leads to a significant reduction in the heating load of the entire building. Results show that during five months of the year, the trombe walls with C, T3SG, T4SG and T designs lead to the reductions of 4710, 5400, 5112 and 5559, kWh in the heating load of the building, respectively. In addition, the most optimal mode, i.e. design T with three directions of radiation absorption, trapezoidal cross-section, and thicker storage wall, leads to the greatest decrease (1637 kWh) in heating load in January.
Implementation and Evaluation of Personal Genetic Testing As Part of Genomics Analysis Courses in German Universities
Authors: Slosarek Tamara , Ibing Susanne , Schormair Barbara , Heyne Henrike O. , Böttinger Erwin P. , Andlauer Till F. M. , Schurmann Claudia 
Published: December 2022

Abstract
Purpose
Due to the increasing application of genome analysis and interpretation in medical disciplines, professionals require adequate education. Here, we present the implementation of personal genotyping as an educational tool in two genomics courses targeting Digital Health students at the Hasso Plattner Institute (HPI) and medical students at the Technical University of Munich (TUM).
Methods
We compared and evaluated the courses and the students’ perceptions on the course setup using questionnaires.
Results
During the course, students changed their attitudes towards genotyping (HPI: 79% [15 of 19], TUM: 47% [25 of 53]). Predominantly, students became more critical of personal genotyping (HPI: 73% [11 of 15], TUM: 72% [18 of 25]) and a majority of students stated that genetic analyses should not be allowed without genetic counseling (HPI: 79% [15 of 19], TUM: 70% [37 of 53]). Students found the personal genotyping component useful (HPI: 89% [17 of 19], TUM: 92% [49 of 53]) and recommended its inclusion in future courses (HPI: 95% [18 of 19], TUM: 98% [52 of 53]).
Conclusion
Students perceived the personal genotyping component as valuable in the described genomics courses. The implementation described here can serve as an example for future courses in Europe.
Coping strategies among adolescents and young adults living with HIV/AIDS in Accra-Ghana
Authors: Dake Selom , Bonful Harriet Affran , Asamoah Alexander , Arthur Hannah Ama , Mwintuu Linus , Asampong Emmanuel , Kretchy Irene A. , Anum Adote 
Published: December 2022

Abstract

Background
Living with HIV/AIDS is remarkably stressful and has an adverse effect on one’s physical and mental health. In Sub-Saharan Africa, the introduction of highly active anti-retroviral therapy has led to an increased number of children with perinatal acquired HIV who are living into adolescence and adulthood. Developing strategies to cope with HIV becomes imperative, especially among these adolescents. The study determined the factors that influence coping strategies among adolescents living with HIV.
Methods
An analytic cross-sectional design was used. 154 adolescents aged 10–19 years living with HIV were systematically sampled at the Fevers Unit of Korle Bu Teaching Hospital from June to December 2021. The adolescent version of the KidCope was used to assess the choice of coping strategies. Stata 16 was used to determine associations between independent variables and the coping strategies identified. Only variables that were significant at p = 0.1 or less in the crude model were used to run the adjusted regression model. The level of significance was set at p = 0.05 with a 95% confidence interval.
Results
The mean age of participants was 19.2 (95%CI-18.7-19.6) years with 51.9% (80/154) of participants being males. A majority, 57.1% (95%CI-52.3%-63.4%) of the participants employed positive coping with 87.0% (135/154) using cognitive restructuring strategy. In an adjusted linear regression model, participants coping strategies were significantly associated with their age 0.96 (95%CI 0.51–1.76, p = 0.046), educational level (p = 0.029), parental status (p = 0.045), caregiver (p = 0.014) as well as dealing with stigma and discrimination (p = 0.008).
Conclusion
Participants largely adopted positive coping strategies in managing the disease. Factors that influenced the choice of coping strategies were increasing age, higher levels of education, and the presence of both parents as caregivers. The importance of a good social support structure and pursuing further education needs to be emphasized in counselling adolescents living with HIV as it promotes the choice of positive coping strategies.
An investigation of the level of stigma and the factors influencing it in the rehabilitation of young and middle-aged stroke patients
Authors: Zheng Zixiu , Song Runluo , Zhao Yunxiao , Lv Hongxia , Wang Yanqing , Yu Cong 
Published: December 2022

Abstract
Background
There are few reported studies on stigma in young and middle-aged stroke patients during the rehabilitation period, however, the rehabilitation period plays a key role in the patients' disease regression. Exploring the level of stigma and the influencing factors in young and middle-aged stroke patients during the rehabilitation period is crucial for determining how to reduce the level of stigma and improve the patients' motivation for rehabilitation treatment. Therefore, this study investigated the level of stigma in young and middle-aged stroke patients and analyzed the factors influencing stigma in order to provide a reference or basis for healthcare professionals to develop effective and targeted stigma intervention programs.
Methods
Using a convenience sampling method, 285 young and middle-aged stroke patients admitted to the rehabilitation medicine department of a tertiary care hospital in Shenzhen, China, from November 2021 to September 2022 were selected and surveyed using a general information questionnaire, the Stroke Patient Stigma Scale, the Barthel Index, and the Positive and Negative Emotions Scale, and multiple linear regression and smoothed curve fitting were used to analyze the factors influencing the stigma of young and middle-aged stroke patients during the rehabilitation period.
Results
Total stigma score of 45.08 ± 11.057, univariate analysis of age, occupation, education level, monthly income before illness, type of health insurance, chronic illness status, primary caregiver, Barthel Index, positive and negative emotion as factors influencing stigma. Multiple linear regression showed that age, monthly income before illness, the Barthel Index, positive and negative emotions were independent influences on stigma in young and middle-aged stroke patients, explaining 58.0% of the total variance in stigma. A smoothed curve fit revealed a curvilinear relationship between the above influences and stigma.
Conclusion
Young and middle-aged stroke patients have a moderate level of stigma. Medical staff should focus on young patients aged 18–44 years, those with high monthly income before the stroke, those with poor self-care ability, and those with low positive and high negative emotion scores, and conduct early assessments and adopt targeted intervention programs according to the influencing factors to reduce the stigma of young and middle-aged stroke patients, improve their motivation for rehabilitation, and help them return to their families and society as soon as possible.
Exploring Effortful Control as a Moderator of the Relationship Between Negative Affect and Child Psychopathology
Authors: Osborne Hanna S. , Palumbo Isabella M. , Tone Erin B. 
Published: December 2022

Abstract
The present study examined unique and interactive effects of effortful control (self-report vs. task-based) on the relationship between negative affect and dimensions of psychopathology in a group of children from the ABCD Study® aged 9–11 (n = 5,432). Results demonstrate that the reactive temperament factor of negative affect showed strong and positive significant associations with both dimensions of psychopathology, while the regulative factor of effortful control showed a significant negative association with both dimensions of psychopathology via Flanker, and a significant positive association with both dimensions of psychopathology via the EATQ-R. These findings raise the possibility that early assessment of effortful control may aid in the identification of early risk profiles for psychopathology and that interventions aimed at maximizing flexible deployment of effort control could help to reduce children’s risk of developing psychopathological symptoms.
Calibration of three-dimensional hot-film data using a collocated sonic anemometer
Authors: Freire Livia , Chamecki Marcelo , Patton Edward 
Published: December 2022

Abstract
In this study, we evaluate hot-film data and test an in situ calibration method from simultaneous sonic anemometer measurements. The details of the calibration are provided, and its performance is validated by comparing results of spectra and structure functions with standard wind-tunnel data and model spectra. A single 3h block of data was selected, containing 33 subblocks of 2 min data without gaps, whose statistics were averaged to provide smooth results. This block was measured above canopy under stable conditions, and it corresponds to a Taylor Reynolds number Reλ ≈ 1550. The agreement with wind tunnel results for a similar Reλ and with model predictions provides a validation for the proposed in situ calibration method. Furthermore, the results indicate a presence of the bottleneck effect in the lateral and vertical spectra, in addition to a lack of inertial range in the second-order structure function due to the low Reynolds number.