bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fasilitasi Deteksi Dini Pneumonia Pada Balita Dengan Menggunakan Media Aplikasi Sebar Pesona (Selamatkan Balita Dari Pneumonia) Di Kota Depok
Authors: Sa'diyah Halimatus , Supriyatna Rahmat , Kasih Bayu Aditya Trisnaning , Ananda Dea Elsa , Kusumaningrum Meliana , Pangestu Riyan , Sarwendah Sarwendah 
Published: September 2023

Pneumonia masih menjadi salah satu penyebab tingginya angka kesakitan dan kematian pada balita saat ini yang salah satunya disebabkan kurangnya pengetahuan ibu. Berdasarkan cakupan penemuan kasus pneumonia yang ditangani di Kota Depok tahun 2018 sebanyak 2.408 (24,39%). Alternatif luaran intervensi pada pelaksanaan Aplikasi ini dibuat dengan tujuan untuk meningkatkan pengetahuan ibu tentang penyakit pneumonia. Penelitian ini dibuat dengan metode observasi secara online melalui google formulir dalam jangka waktu April hingga September 2021 di wilayah Kota Depok dengan sasaran ibu yang mempunyai balita sebanyak 20 orang. Berdasarkan hasil yang di dapat dari pretest terdapat 13 orang yang masih belum mengetahui tentang penyakit pneumonia dan berdasarkan hasil post test terdapat peningkatan pengetahuan ibu terhadap penyakit Pneumonia dengan melihat nilai akurasi dari pre test dan post test. Kegiatan ini memiliki kekurangan yaitu jaringan internet yang kurang stabil. Materi aplikasi yang disampaikan mendapat respon yang cukup baik dari responden. Kesimpulan kegiatan ini adalah mengenalkan produk luaran dalam bentuk aplikasi yang berisi tentang edukasi pencegahan penyakit pneumonia pada balita. Diharapkan kepada ibu yang mempunyai balita dapat mempelajari tentang pneumonia pada balita dengan menggunakan media digital berupa aplikasi atau media pembelajaran lainnya sehingga dapat meningkatkan pengetahuan ibu tentang penyakit pneumonia pada balita.
Pengaruh Keterampilan Manajerial Kepala Sekolah, Supervisi Akademik, Budaya Sekolah Terhadap Kinerja Guru
Authors: Laila Cahya Pratiwi  , Titi Prihatin  , Tri Joko Raharjo  
Published: September 2023

Tujuan yang hendak dicapai dalam penelitian ini adalah untuk untuk menganalisis serta mengetahui pengaruh antar variabel Keterampilan manajerial kepala sekolah, supervisi akademik, serta budaya sekolah terhadap kinerja guru. Jenis penelitian ini adalah penelitian kuantitatif menggunakan desain penelitian Ex-Post Facto dengan teknik analisis regresi berganda. Populasi dalam penelitian ini menggunakan guru SD Kecamatan Suradadi Kabupaten Tegal. Sampel yang diambil adalah 60 Guru dengan menggunakan stratified random sampling. Data dalam penelitian ini diperoleh melalui angket, observasi, dan dokumentasi. Berdasarkan hasil analisis regresi berganda yang telah dilakukan variabel keterampilan manajerial kepala sekolah nilai signifikansi (0,027 < 0,05), variabel supervisi akademik nilai signifikansi (0,034 < 0,05), variabel budaya sekolah nilai signifikansi (0,028 < 0,05). Disimpulkan bahwa terdapat pengaruh antara variabel keterampilan manajerial kepala sekolah, supervisi akademik, budaya sekolah terhadap kinerja guru. Berdasarkan hasil penelitian ini saran yang dapat disimpulkan adalah keterampilan manajerial kepala sekolah, supervisi akademik, dan budaya sekolah saling mempengaruhi dan meningkatkan kinerja guru dalam meningkatkan kinerja guru dan staf terkait pelaksanaan tugas pokok dan fungsinya.
Efeito do ambiente sobre as respostas fisiológicas de caprinos criados em clima quente recebendo diferentes fontes de volumoso
Authors: Moura Danívia Maria Ferreira de , Santos Neilson Silva , Silva José Crisólogo de Sales , Oliveira Alex Romualdo Nunes de , Abdalla Adibe Luiz 
Published: September 2023

Objetivou-se avaliar os efeitos do ambiente ntas respostas fisiológicas dos caprinos sem raça definida, sob as condições do semiárido em Santana do Ipanema. Utilizou-se 30 caprinos na faixa de um ano de idade e peso médio entre 24 e 28 kg. Estudou-se os seguintes parâmetros: temperatura retal (TR) onde foi introduzido um termômetro clínico, diretamente do reto do animal, frequência respiratória (FR) obtida pela auscultação indireta das bulhas. Os batimentos foram obtidos com um estetoscópio colocado diretamente na região torácica esquerda, contando-se o número de batimentos durante 20 segundos. A temperatura e umidade relativa do ar foram registradas através de um psicrômetro portátil na área experimental. Os parâmetros fisiológicas e ambientais foram registrados a cada 3 horas. As amostras de sangue de cada animal foram retiradas a cada 8 dias, realizando o eritrograma (contagem de hemácias, hematócrito e hemoglobina), e o leucograma (contagem total de leucócitos). Os dados obtidos foram avaliados estatisticamente por meio do Teste de Tukey em nível de significância de 5%. Observou-se que a TR não sofreu efeito das dietas, mantendo-se acima da faixa normal em todas as dietas. Já as FR e FC sofreram efeito significativo (p< 0,05) mantendo-se também acima do ideal. O histograma apresentou segmentados, linfócitos, monócitos e bastonetes com diferenças significativas, mas dentro do ideal para a espécie. Pode-se concluir que os parâmetros observados sofreram mais influência do clima, do que da fonte de volumoso, sendo seguro utilizar todas as dietas estudadas.
Projeto terapêutico singular como ferramenta de abordagem familiar durante a visita domiciliar
Authors: Napoleão Franco Magnago , Bezerra Mariana Torres , Xavier Mayza Mendonça , Souza Bruno Henrique de Oliveira , Apratto Junior Paulo Cavalcante , Chevitarese Leila , Ney Márcia Silveira 
Published: September 2023

O Projeto Terapêutico Singular (PTS), principal ferramenta de trabalho da Estratégia Saúde da Família (ESF) na Atenção Básica à Saúde, possibilita a integralidade do cuidado. O objetivo do artigo foi de descrever as etapas que constituíram a construção de um PTS em conjunto com o paciente e sua rede de apoio no cenário de prática em uma comunidade em Duque de Caxias, RJ, possibilitando retratar a importância dessa ferramenta de abordagem familiar durante a Visita Domiciliar. Trata-se de um relato de experiência de acadêmicos do curso de Medicina da Universidade Unigranrio Afya. A construção do PTS favoreceu a elaboração em conjunto do plano terapêutico e, consequentemente, do fortalecimento de vínculo, visto que o projeto foi feito pelos acadêmicos, seus docentes, a Agente Comunitária de Saúde (ACS) da Unidade Básica de Saúde (UBS) local, o paciente e sua rede de apoio. Assim, a experiência possibilitou um enriquecimento teórico-prático para formação pessoal e profissional além de uma visão ampliada da dinâmica familiar e do processo de adoecimento, favorecendo, portanto, a gestão do cuidado.
Identifikasi Perilaku Berkendara Mahasiswa Kota Bandung Menggunakan Driver Behaviour Questionnaire (DBQ)
Authors: Halim Winda , Caroline Cristy 
Published: September 2023

According to data from the Central Statistics Agency of West Java Province, the number of accidents in Bandung is quite high. The number of traffic accidents with victims as college students in Bandung is in the 3rd highest rank among other big cities. Of all accidents that occur, the driver's behaviour is the main cause of the accident. Therefore, the purpose of this study is to analyze driving behaviour and the factors of deviant driving behaviour carried out by student drivers in Bandung and analyze the relationship between gender, area of ​​residence, driving experience, and driving frequency on driving behaviour.
This research was conducted by distributing the Driver Behaviour Questionnaire (DBQ) to determine the deviant driving behaviour of the respondents. There are 154 respondent data that will be used in this study. The data that will be collected in this study is the respondent's profile and 59 items of driving behaviour statements. The results of data collection will be processed by testing Bivariate Correlation and comparison of the average value of driving behaviour. There are several driving behaviour variabels related to the independen variabel as well as several preventive and punishment efforts given to overcome the deviant driving behaviour.
FAKTOR-FAKTOR YANG MEMPENGARUHI KEPUTUSAN PEMBELIAN PRODUK
Authors: Pasmawati Yanti , Pegi Andrian M 
Published: September 2023

In this modern era, competition in the business world is getting tougher. Every company is competing to market their products or services according to the growing trend among consumers. Likewise in the furniture business which is also starting to develop quite rapidly in Indonesia. The company basically wants to be the market leader in the competition faced in the business world. PT Pratama Tunggu Tubang is one of the PTs working in the timber industry. Based on the results of this study, simultaneously the product design variable (X1) and product quality variable (X2) in this study have a positive and significant effect on purchasing decisions (Y) on PT consumers Primary Wait Tubang. This is evidenced by the results of calculations from SPSS obtained f count 291.751> f table 3.150, so it can be concluded that the product design variable (X1) and product quality variable (X2) have a simultaneous effect on the purchase decision variable (Y).
Keywords: design product,, product, quality product, purchase decision
Value added analysis on the processing of frozen tuna in PT. Kelola Mina Laut at Ocean Fishing Port of Kendari Southeast Sulawesi
Authors: Septiyanti Feni , Yusuf Sarini , Huli La Ode , Budiyanto  , Riani Irdam , Sriwulan Desy 
Published: September 2023

Tuna is one of the important economical fishery commodities exported in frozen form. One of the companies that develops a frozen tuna processing business in Kendari City is the company PT. Manage Mina Laut Kendari Ocean Fishing Port This study aims to analyze how much added value pt. Manage Mina Laut in March 2022. This research uses the case study method with data collection through interviews, observations, documentation, and literature studies. Interviews wre conducted to respondents consisting of one company manager and 3 representatives of each employee division and one supervisor of PT Kelola Mina Laut. The analysis used is a quantitative analysis, namely the added value obtained is calculated using the formula NTP (Product Added Value) = NP – Na (NTP = Product Added Value, NP = Product Value, and Na = Intermediate Cost Value). Production in this study was calculated for 26 times a month as carried out by the company. The results showed that the average added value of the product was IDR 28,939,353/production with a value-added ratio of 26.91% for each production cycle. The added value obtained by PT. Kelola Mina Laut at PPS Kendari was low. It is necessary to increase the amount of production with careful consideration on raw materials and packaging. The high price of raw materials and plastic packaging contributes to the suboptimal added value
The Effect of Layer Thickness and Light Intensity on the Degree of Conversion, Microhardness and Cytotoxicity of Bulk Fill Composite Resins
Authors: BATMAZ Sevde Gül , DÜNDAR Ayşe , BARUTÇUGİL Çağatay 
Published: September 2023

Objectives: The aim of this study was to evaluate the effects of polymerizing bulk fill composite resins at different thicknesses and different light intensities on the degree of conversion, microhardness and cytotoxicity of the composites.
Methods: Two different bulk fill composite resins were used in this in vitro study: Sonic Fill 2, Filtek Bulk Fill. Samples prepared from both composites with a thickness of 2, 4 and 6 mm were polymerized in 2 different power modes. The degree of conversion, microhardness and cytotoxicity of these samples were measured.
Results: As the layer thickness of the bulk fill composite resins increased, the degree of conversion of the lower surfaces of the composites decreased significantly (p
WeChat online visual language among Chinese Gen Z: virtual gift, aesthetic identity, and affection language
Authors: Liu Ruoxi 
Published: September 2023

IntroductionAs a relatively new and innovative form of digital communication and visual image, emojis, emoticons, and stickers are appreciated, yet criticised. Young people on social media have lost the traditional social etiquette and interpersonal networking skills, which is a challenge in itself. This study provides a better understanding of how young people engage and behave in diverse interpersonal contexts while utilising digital visual language.MethodsThis study contributes to digital anthography and social media studies, by conducting this study through interviews with 10 Generation Z young people from urban China and a 2-month-long participatory observation of three WeChat group chats.ResultsBy examining how young people use WeChat visual language in relationships with their elders or superiors, equivalent peers and intimate lovers or friends, this study found that emoticons and stickers become virtual gifts, aesthetic identities and the affection language of Generation Z.DiscussionThis study contends that digital visual languages and new media do not alter human nature or ethical standards but rather provide new avenues for expression and empower human affective communication. Although the core of traditional etiquette is still being passed on and absorbed, its form has changed.
The newly proposed alanine aminotransferase to high-density lipoprotein cholesterol ratio has shown effectiveness in identifying non-alcoholic fatty liver disease
Authors: Qiu Jiajun , Kuang Maobin , Yang Ruijuan , Yu Changhui , He Shiming , Sheng Guotai , Zou Yang 
Published: September 2023

ObjectiveAlanine aminotransferase (ALT) and high-density lipoprotein cholesterol (HDL-C) are important predictive factors for non-alcoholic fatty liver disease (NAFLD). The aim of this study was to analyze the association between the ALT/HDL-C ratio and NAFLD.MethodsWe conducted a retrospective analysis of data from 14,251 individuals participating in the NAGALA project’s health screening program. The presence of NAFLD was diagnosed based on the participants’ alcohol consumption status and liver ultrasonography images. Multivariable logistic regression models were used to assess the association between the ALT/HDL-C ratio and NAFLD. Receiver operating characteristic (ROC) analysis was performed to determine and compare the effectiveness of ALT, HDL-C, the aspartate aminotransferase to HDL-C (AST/HDL-C) ratio, the gamma-glutamyl transferase to HDL-C (GGT/HDL-C) ratio and the ALT/HDL-C ratio in identifying NAFLD.ResultsWe observed a significant positive association between the ALT/HDL-C ratio and the prevalence of NAFLD. For each standard deviation (SD) increase in the ALT/HDL-C ratio, the adjusted odds ratio (OR) for NAFLD among the participants was 3.05 [95% confidence interval (CI): 2.63, 3.53], with the highest quartile of ALT/HDL-C ratio having a 9.96-fold increased risk compared to the lowest quartile. In further subgroup analyses stratified by gender, age, and waist circumference (WC), we observed a significantly higher risk of NAFLD associated with the ALT/HDL-C ratio among individuals aged ≥45 years, males, and those who were abdominal obesity. Furthermore, based on the results of ROC analysis, we found that the ALT/HDL-C ratio [area under the curves (AUC): 0.8553] was significantly superior to ALT, HDL-C, AST/HDL-C ratio and GGT/HDL-C ratio in identifying NAFLD (All Delong P&lt;0.05); the threshold of suggested ALT/HDL-C ratio for identifying NAFLD was 15.97.ConclusionThis population-based study demonstrates a positive association between the ALT/HDL-C ratio and NAFLD. The ALT/HDL-C ratio can effectively identify individuals with NAFLD.
Prognostic utility of TME-associated genes in pancreatic cancer
Authors: Nie Yuanhua , Xu Longwen , Bai Zilong , Liu Yaoyao , Wang Shilong , Zeng Qingnuo , Gao Xuan , Xia Xuefeng , Chang Dongmin 
Published: September 2023

Background: Pancreatic cancer (PC) is a deadly disease. The tumor microenvironment (TME) participates in PC oncogenesis. This study focuses on the assessment of the prognostic and treatment utility of TME-associated genes in PC.Methods: After obtaining the differentially expressed TME-related genes, univariate and multivariate Cox analyses and least absolute shrinkage and selection operator (LASSO) were performed to identify genes related to prognosis, and a risk model was established to evaluate risk scores, based on The Cancer Genome Atlas (TCGA) data set, and it was validated by external data sets from the Gene Expression Omnibus (GEO) and Clinical Proteomic Tumor Analysis Consortium (CPTAC). Multiomics analyses were adopted to explore the potential mechanisms, discover novel treatment targets, and assess the sensitivities of immunotherapy and chemotherapy.Results: Five TME-associated genes, namely, FERMT1, CARD9, IL20RB, MET, and MMP3, were identified and a risk score formula constructed. Next, their mRNA expressions were verified in cancer and normal pancreatic cells. Multiple algorithms confirmed that the risk model displayed a reliable ability of prognosis prediction and was an independent prognostic factor, indicating that high-risk patients had poor outcomes. Immunocyte infiltration, gene set enrichment analysis (GSEA), and single-cell analysis all showed a strong relationship between immune mechanism and low-risk samples. The risk score could predict the sensitivity of immunotherapy and some chemotherapy regimens, which included oxaliplatin and irinotecan. Various latent treatment targets (LAG3, TIGIT, and ARID1A) were addressed by mutation landscape based on the risk model.Conclusion: The risk model based on TME-related genes can reflect the prognosis of PC patients and functions as a novel set of biomarkers for PC therapy.
A serum metabolic biomarker panel for early rheumatoid arthritis
Authors: Rodríguez-Muguruza Samantha , Altuna-Coy Antonio , Arreaza-Gil Verónica , Mendieta-Homs Marina , Castro-Oreiro Sonia , Poveda-Elices Maria José , del Castillo-Piñol Nuria , Fontova-Garrofé Ramon , Chacón Matilde R. 
Published: September 2023

ObjectiveThere is an urgent need for novel biomarkers to improve the early diagnosis of rheumatoid arthritis (ERA). Current serum biomarkers used in the management of ERA, including rheumatoid factor and anti-cyclic citrullinated peptide (ACPA), show limited specificity and sensitivity. Here, we used metabolomics to uncover new serum biomarkers of ERA.MethodsWe applied an untargeted metabolomics approach including gas chromatography time-of-flight mass spectrometry in serum samples from an ERA cohort (n=32) and healthy controls (n=19). Metabolite set enrichment analysis was performed to explore potentially important biological pathways. Partial least squares discriminant analysis and variable importance in projection analysis were performed to construct an ERA biomarker panel.ResultsSignificant differences in the content of 11/81 serum metabolites were identified in patients with ERA. Receiver operating characteristic (ROC) analysis showed that a panel of only three metabolites (glyceric acid, lactic acid, and 3-hydroxisovaleric acid) could correctly classify 96.7% of patients with ERA, with an area under the ROC curve of 0.963 and with 94.4% specificity and 93.5% sensitivity, outperforming ACPA-based diagnosis by 2.9% and, thus, improving the preclinical detection of ERA. Aminoacyl-tRNA biosynthesis and serine, glycine, and phenylalanine metabolism were the most significant dysregulated pathways in patients with ERA.ConclusionA metabolomics serum-based biomarker panel composed of glyceric acid, lactic acid, and 3-hydroxisovaleric acid offers potential for the early clinical diagnosis of RA.
Optimizing rheological properties for printability: low-temperature extrusion 3D printing of hydroxyapatite-polycaprolactone mixture inks for bone tissue engineering
Authors: Yan Ming , Awad Hani A. 
Published: September 2023

Introduction: Low-temperature extrusion three-dimensional printing (LTE-3DP) using viscous ceramic-polymer inks has shown promise for bone tissue engineering. This process involves formulating a flowable ink by combining ceramic powders and other components with organic or inorganic polymer solutions, which can then be extruded through a 3D printer nozzle. LTE-3DP allows the incorporation of high fractions of bioactive ceramics and thermally labile additives such as drugs, proteins, and biomolecules into the inks to promote osteogenesis and bone regeneration. The rheology of the ink, influenced by various variables, significantly impacts the printability and form fidelity of the resulting scaffolds. These variables include the composition of the polymer solution and the size and weight ratio of ceramic microparticles. In this study, we posited that the printability of hydroxyapatite (HA) and polycaprolactone (PCL) mixture inks could be optimized by tailoring their rheological properties.Methods: We conducted a systematic investigation, varying the PCL weight percentage and HA:PCL weight ratio, to examine the effects of the ink’s composition on its viscosity and storage modulus, as well as its printability and the mechanical properties of 3D printed HA:PCL scaffolds.Results: We demonstrated that HA:PCL inks exhibit predictable non-Newtonian fluid behavior at higher fractions of HA, displaying significant shear thinning at elevated shear rates, which can facilitate extrusion through a 3D printing nozzle. We identified printable ink compositions based on filament continuity and scaffold form fidelity criteria. Moreover, we performed computational simulations to analyze the ink flow through an extrusion nozzle. These simulations utilized the Herschel-Bulkley-Papanastasiou constitutive model, considering the rheological properties obtained from experimental measurements. By combining experimental measurements and computational simulations, we formulated a non-dimensional Printability number that predicts whether an ink is printable based on the ink’s rheological parameters and printer-specific factors. Furthermore, we evaluated the compressive properties of printed HA:PCL scaffolds and characterized the effects of PCL% and HA:PCL ratio on the hyperelasticity observed in response to compressive deformations.Discussion: This hybrid approach using experimental rheology and FE simulations provides a framework to define the printability of ceramic-polymer ink formulations, which could help streamline the 3D printing of novel inks for bone tissue engineering.
The impact of COVID-19 pandemic on orthodontic services and trainees’ mental health in India
Authors: Thiruvenkatachari Badri , Sivakumar Prema , Ananth Sanjana , Sabbagh Yana , Lewis Benjamin R. K. , Chadwick Stephen M. , Kaliyaperumal Gnana Shanmugam , Batra Panchali 
Published: September 2023

AimTo evaluate the impact of COVID-19 on clinical orthodontic services, orthodontic education, and the emotional well-being of orthodontists and orthodontic trainees in India.Materials and methodsThe survey was designed using Survey Monkey™ and distributed to members of the Indian Orthodontic Society via their registered email address and also via social media platforms (WhatsApp and LinkedIn).ResultsA total of 610 responses to the survey were received. The majority of respondents agreed on the negative impact of COVID-19 on clinical activity and the associated income of orthodontists. Respondents reported that this was mainly due to national restrictions (70.1%), increased cross infection measures (59.6%), state restrictions (55.9%), and social distancing (39.4%). Ninety one percent of respondents agreed that orthodontic staff should have evidence of vaccination before providing care.COVID-19 was found to have a negative impact on the trainees’ perceptions of their clinical dexterity (72.4%), their confidence with respect to academic knowledge (66.5%), their mental health (80.7%), and their stress levels during the pandemic (93.2%).ConclusionThe COVID-19 pandemic has had a negative impact on orthodontic specialists and post-graduate trainees in India. The impact on trainees’ mental health was significantly higher compared to trainees from other countries. Decreased clinical activity has reduced the opportunities for learning, and trainers must rise to the challenge of providing additional support to this cohort of trainees who will progress to become the future orthodontic workforce.