bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nonsecretor Phenotype Is Associated With Less Risk of Rotavirus-Associated Acute Gastroenteritis in a Vaccinated Nicaraguan Birth Cohort
Authors: Reyes Yaoska , St Jean Denise T , Bowman Natalie M , González Fredman , Mijatovic-Rustempasic Slavica , Becker-Dreps Sylvia , Svensson Lennart , Nordgren Johan , Bucardo Filemón , Vielot Nadja A 
Published: June 2023

Abstract

Background
Histo-blood group antigens (HBGAs) have been associated with rotavirus vaccine take; but the effect of these HBGAs on rotavirus incidence and risk remains poorly explored in vaccinated populations.

Methods
Rotavirus-associated acute gastroenteritis (AGE) was assessed in 444 Nicaraguan children followed from birth until 3 years of age. AGE episodes were tested for rotavirus by reverse-transcription quantitative polymerase chain reaction, and saliva or blood was used to determine HBGA phenotypes. Cox proportional hazards models were used to estimate the relative hazard of rotavirus AGE by HBGA phenotypes.

Results
Rotavirus was detected in 109 (7%) stool samples from 1689 AGE episodes over 36 months of observation between June 2017 and July 2021. Forty-six samples were successfully genotyped. Of these, 15 (35%) were rotavirus vaccine strain G1P[8], followed by G8P[8] or G8P[nt] (11 [24%]) and equine-like G3P[8] (11 [24%]). The overall incidence of rotavirus-associated AGE was 9.2 per 100 child-years, and was significantly higher in secretor than nonsecretor children (9.8 vs 3.5/100 child-years, P = .002).

Conclusions
The nonsecretor phenotype was associated with decreased risk of clinical rotavirus vaccine failure in a vaccinated Nicaraguan birth cohort. These results show the importance of secretor status on rotavirus risk, even in vaccinated children.
Collaborative benchmarking of functional-structural root architecture models: Quantitative comparison of simulated root water uptake
Authors: Schnepf Andrea , Black Christopher K , Couvreur Valentin , Delory Benjamin M , Doussan Claude , Heymans Adrien , Javaux Mathieu , Khare Deepanshu , Koch Axelle , Koch Timo , Kuppe Christian W , Landl Magdalena , Leitner Daniel , Lobet Guillaume , Meunier Félicien , Postma Johannes A , Schäfer Ernst D , Selzner Tobias , Vanderborght Jan , Vereecken Harry 
Published: June 2023

Abstract
Functional-structural root architecture models have evolved as tools for the design of improved agricultural management practices and for the selection of optimal root traits. In order to test their accuracy and reliability, we present the first benchmarking of root water uptake from soil using five well-established functional-structural root architecture models: DuMux, CPlantBox, R-SWMS, OpenSimRoot and SRI. The benchmark scenarios include basic tests for water flow in soil and roots as well as advanced tests for the coupled soil-root system. The reference solutions and the solutions of the different simulators are available through Jupyter Notebooks on a GitHub repository. All of the simulators were able to pass the basic tests and continued to perform well in the benchmarks for the coupled soil-plant system. For the advanced tests, we created an overview of the different ways of coupling the soil and the root domains as well as the different methods used to account for rhizosphere resistance to water flow. Although the methods used for coupling and modelling rhizosphere resistance were quite different, all simulators were in reasonably good agreement with the reference solution. During this benchmarking effort, individual simulators were able to learn about their strengths and challenges, while some were even able to improve their code. Some now include the benchmarks as standard tests within their codes. Additional model results may be added to the GitHub repository at any point in the future and will be automatically included in the comparison.
Bearing Witness and Creative Activism
Authors: Bacharach Sondra 
Published: June 2023

AbstractIn this article, I explore the relationship between witness-bearing arts as a form of creative activism designed to respond to social injustices. In the first section, I present some common features of bearing witness, as conceptualized within media studies and journalism. Then I explain how artworks placed in the streets can bear witness in a similar way. I argue that witness-bearing art transmits knowledge about certain unjust and harmful events, which then places a moral burden or responsibility on the viewer. To defend this view, I offer some examples of activist art that bears witness to certain events. I suggest that witness-bearing art is placed in the streets in order to make certain truths publicly available, by offering evidence of them embedded in the artwork. The final section considers why the bearing witness is especially effective for activist art. Witness-bearing art plays a crucial knowledge-transmitting function, one which enables art to engage in creative activism. I conclude by considering how witness-bearing art offers a powerful and persuasive voice for the oppressed.
Animal Deities, Domestication, and the Purpose of Control in Contemporary Singaporean Mediumship
Authors: Strange Stuart Earle 
Published: June 2023

Abstract
This article considers how to study the meanings of control in religious life and multispecies relations. In it, I examine how contemporary Singaporean deity mediums, who describe themselves as subject to an absolute form of control while possessed, interpret what this control should be like. By treating mediums’ self-described subordination as analogous to that of domestic animals’ relations to humans, I explore common problems with control shared between religious and multispecies studies. In doing so, I examine core issues that point to how control can be more effectively conceptualized and analyzed by paying attention to the ways religious practices shape the interpretation of purpose. The article contends that any effective theory of control must explore how what it means to be controlled is embedded in the ways that different religious traditions perceive the purposes of the relations that make the subjects of control interpretable to themselves and others.
A snapshot of artificial intelligence research 2019–2021: is it replacing or assisting physicians?
Authors: Elmahdy Mahmoud , Sebro Ronnie 
Published: June 2023

Abstract
Artificial intelligence (AI) has the potential to be a disruptive technology in healthcare. Recently, there is increased speculation that AI may be used to replace healthcare providers in the future. To answer this question, we reviewed over 21 000 articles published in medical specialty journals between 2019 and 2021 to evaluate whether these AI models were intended to assist or replace healthcare providers. We also evaluated whether all Food and Drug Administration (FDA)-approved AI models were used to assist or replace healthcare providers. We find that most AI models published in this time period were intended to assist rather than replace healthcare providers, and that most of the published AI models performed tasks that could not be done by healthcare providers.
Effect of withdrawing an immunomodulatory feed additive from lactating cow diets on peripheral blood mononuclear cell proliferation
Authors: Marins Thiago N , Calix Jainer O S , Orellana Rivas Ruth M , Bernard John K , Garcia Miriam , Chapman James D , Kirk David J , Tao Sha 
Published: June 2023

Abstract
Supplementation of immunomodulatory feed additives, such as OmniGen AF (OG), helps to maintain immune competency; however, it is unknown if immune benefits persist in lactating cows after OG is removed from the diet. The aim of this trial was to evaluate the effect of withdrawing OG from the diet on peripheral blood mononuclear cells (PBMC) proliferation of midlactation dairy cows. Multiparous Holstein cows (N = 32), blocked by parity (2.7 ± 0.8) and days in milk (153 ± 39 d) were randomly assigned to one of the two dietary treatments within each block: diets were top dressed with either OG (56 g/d/cow) or placebo (CTL, 56 g/d/cow). Cows were housed in the same free-stall pen and individually fed once per day through Calan gates. All cows were fed the same diet containing OG for at least 1 yr before the onset of treatments. Cows were milked three time per day and milk yield was recorded at each milking. Milk samples were collected from three consecutive milkings weekly and composition analyzed. Body weight (BW) and condition score were measured weekly. Blood samples were collected at −1, 1, 3, 5, and 7 wk relative to the onset of treatments for the isolation of PBMC. The PBMC were cultured with concanavalin A (ConA) and lipopolysaccharides (LPS) for 72 h in vitro to determine proliferative responses. Prior to the experiment, cows in both treatments had similar disease incidence. During the experiment, cows did not show symptoms of disease. Withdrawing OG from the diet did not affect (P ≥ 0.20) milk yield or composition, intake, or BW. Compared with CTL, feeding OG maintained greater body condition score (2.83 vs. 2.92, P = 0.04). Regardless of time, relative to CTL, PBMC isolated from cows fed with OG had a greater proliferative rate when stimulated with LPS (stimulation index: 1.27 vs. 1.80, P = 0.05) and tended to have greater proliferation when stimulated with ConA (stimulation index: 5.24 vs. 7.80, P = 0.08). In conclusion, withdrawing OG from the diet of midlactation cows reduced proliferative response of PBMC suggesting that the immunomodulatory role of OG is lost as early as 1 wk after its withdrawal from the diet of lactating dairy cows.
A systems approach to evaluate nitrogen utilization efficiency and environmental impacts of swine growing-finishing feeding programs in U.S. pork production systems
Authors: Yang Zhaohui , Urriola Pedro E , Johnston Lee J , Shurson Gerald C 
Published: June 2023

Abstract
Traditionally, swine diets have been formulated to meet nutrient requirements at the lowest cost with little regard toward minimizing environmental impacts. The overall objective of this study was to evaluate the relative differences among four grower-finisher feeding programs, using precision diet formulation practices, on growth performance, carcass composition, nitrogen utilization efficiency, and environmental impacts. In experiment 1, four 4-phase growing-finishing feeding programs consisting of diets containing corn and soybean meal (CSBM), low protein CSBM supplemented with crystalline amino acids (LP), CSBM with 30% distillers dried grains with solubles (DDGS), and DDGS supplemented with crystalline Ile, Val, and Trp (DDGS + IVT) were fed to 288 mixed sex pigs (initial body weight [BW] = 36.9 ± 4.2 kg) for 12 wk to determine effects on growth performance and carcass characteristics. Pigs fed with CSBM had greater (P &lt; 0.05) final BW than those fed with LP and DDGS, and greater gain efficiency than pigs fed with LP. Pigs fed with DDGS + IVT tended to have greater (P = 0.06) backfat depth than pigs fed with DDGS, and less (P &lt; 0.05) loin muscle area than pigs fed with CSBM. In experiment 2, nitrogen (N) and phosphorus (P) balance of barrows (n = 32; initial BW = 59.9 ± 5.1 kg) fed with each of the phase-2 diets from experiment 1 was determined in a 12-d metabolism study (7 d adaptation and 5 d collection). Pigs fed with CSBM had a greater (P &lt; 0.05) amount of N retained than pigs fed with other diets, but also had a greater (P &lt; 0.05) amount of urinary N excretion and blood urea N than pigs fed with LP and DDGS + IVT diets. Pigs fed with LP tended (P = 0.07) to have the greatest N utilization efficiency but the least (P &lt; 0.05) P retained as a percentage of P intake among dietary treatments. Diet composition and data collected from experiments 1 and 2 were used to calculate life cycle assessment environmental impacts using Opteinics software (BASF, Lampertheim, Germany). The CSBM feeding program had the least impact on climate change, marine and freshwater eutrophication, and fossil resource use. The LP feeding program had the least impact on acidification, terrestrial eutrophication, and water use, while the DDGS feeding programs had the least impact on land use. These results indicate that feeding CSBM diets optimized growth performance and carcass composition while simultaneously reducing impacts on climate change, marine and freshwater eutrophication, and fossil resource use compared with the other feeding programs evaluated.
A new genus of Madagascan freshwater crab to accommodate Hydrothelphusa vencesi Cumberlidge, Marijnissen & Thompson, 2007 (Brachyura: Potamoidea: Deckeniidae), and the description of two new congeners
Authors: Cumberlidge Neil , Soma Julia B , Leever Ellen M , Daniels Savel R 
Published: June 2023

Abstract
Nheena n. gen. is established to accommodate the Madagascan freshwater crab Hydrothelphusa vencesi Cumberlidge, Marijnissen & Thompson, 2007 that was formerly included in Hydrothelphusa A. Milne-Edwards, 1872. In addition, N. museonatoran. sp. and N. artiareginan. sp. are established and these new taxa are recognized based on a combination of morphological characters and previous molecular data; are all illustrated. The three species assigned to Nheenan. gen. are compared with each other and with other species of freshwater crabs found in Madagascar, and a map of their distribution is included.
Population changes of Bemisia tabaci (Hemiptera: Aleyrodidae) on different colored poinsettia leaves with different trichome densities and chemical compositions
Authors: Shi Pei-Qiong , Liu Jing , Ye Jun-Xi , Zhang Ting-Zhen , Lin Yu-Chun , Lao Qiao-Bin , Qiu Bao-Li , Zhou Hong-Kai , Xu Jin 
Published: June 2023

Abstract
The whitefly, Bemisia tabaci, is a destructive and invasive pest of many horticultural plants including poinsettia (Euphorbia pulcherrima). Outbreaks of B. tabaci cause serious damage by direct feeding on phloem sap, and spreading 100+ plant viruses to crops. Bemisia tabaci were observed more frequently on green than red poinsettia leaves, and the factors responsible for this are unknown. Here, we investigated the development rate, survivorship, fecundity of B. tabaci feeding on green versus red leaves, as well as the leaves’ volatiles, trichome density, anthocyanin content, soluble sugars, and free amino acids. Compared to red leaves, B. tabaci on green leaves showed increased fecundity, a higher female sex ratio, and survival rate. The green color alone was more attractive to B. tabaci than red. Red leaves of poinsettia contained more phenol, and panaginsene in their volatiles. Alpha-copaene and caryophyllene were more abundant in the volatiles of poinsettia green leaves. Leaf trichome density, soluble sugars and free amino acids were higher in green than red leaves of poinsettia, anthocyanin was lower in green than red leaves. Overall, green leaves of poinsettia were more susceptible and attractive to B. tabaci. The morphological and chemical variation between red and green leaves also differed; further investigation may reveal how these traits affect B. tabaci’s responses.
Entomopathogens infecting brown marmorated stink bugs before, during, and after overwintering
Authors: Hajek Ann E , Brandt Samuel N , González Jennifer B , Bergh J Christopher 
Published: June 2023

AbstractThe microsporidian, Nosema maddoxi Becnel, Solter, Hajek, Huang, Sanscrainte & Estep, infects brown marmorated stink bug, Halyomorpha halys (Stål) (Hemiptera: Pentatomidae), populations in North America and Asia and causes decreased fitness in infected insects. This host overwinters as adults, often in aggregations in sheltered locations, and variable levels of mortality occur over the winter. We investigated pathogen prevalence in H. halys adults before, during, and after overwintering. Population level studies resulted in detection of N. maddoxi in H. halys in 6 new US states, but no difference in levels of infection by N. maddoxi in autumn versus the following spring. Halyomorpha halys that self-aggregated for overwintering in shelters deployed in the field were maintained under simulated winter conditions (4°C) for 5 months during the 2021–2022 winter and early spring, resulting in 34.6 ± 4.8% mortality. Over the 2020–2021 and 2021–2022 winters, 13.4 ± 3.5% of surviving H. halys in shelters were infected with N. maddoxi, while N. maddoxi infections were found in 33.4 ± 10.8% of moribund and dead H. halys that accumulated in shelters. A second pathogen, Colletotrichum fioriniae Marcelino & Gouli, not previously reported from H. halys, was found among 46.7 ± 7.8% of the H. halys that died while overwintering, but levels of infection decreased after overwintering. These 2 pathogens occurred as co-infections in 11.1 ± 5.9% of the fungal-infected insects that died while overwintering. Increasing levels of N. maddoxi infection caused epizootics among H. halys reared in greenhouse cages after overwintering.
Engaging with the Nagoya Protocol on Access and Benefit-Sharing: recommendations for noncommercial biodiversity researchers
Authors: Colella Jocelyn P , Silvestri Luciana , Súzan Gerardo , Weksler Marcelo , Cook Joseph A , Lessa Enrique P 
Published: June 2023

Abstract
The Convention on Biological Diversity and the Nagoya Protocol on Access and Benefit-Sharing provide an international legal framework that aims to prevent misappropriation of the genetic resources of a country and ensure the fair and equitable sharing of benefits arising from their use. The legislation was negotiated at the behest of lower-income, biodiverse countries to ensure that benefits derived from research and development of genetic resources from within their jurisdictions were equitably returned and could thereby incentivize conservation and sustainable use of biodiversity. Despite good intentions, however, rapid adoption of access and benefit-sharing measures at the national level, often without participatory strategic planning, has hampered noncommercial, international collaborative genetic research with counterproductive consequences for biodiversity conservation and sustainable use. We outline how current implementation of the Convention of Biological Diversity and the Nagoya Protocol affect noncommercial research, such as that conducted in many disciplines in biology, including mammalogy. We use a case study from Brazil, an early adopter, to illustrate some current challenges and highlight downstream consequences for emerging pathogen research and public health. Most emerging pathogens colonize or jump to humans from nonhuman mammals, but noncommercial research in zoonotic diseases is complicated by potential commercial applications. Last, we identify proactive ways for the mammalogical community to engage with the Convention on Biological Diversity and the Nagoya Protocol, through sharing of nonmonetary benefits and working with local natural history collections. Leveraging international scientific societies to collectively communicate the needs of biodiversity science to policy makers will be critical to ensuring that appropriate accommodations are negotiated for noncommercial research.
Patterns of post-hibernation wing damage healing in little brown bats (Myotis lucifugus) impacted by white-nose syndrome
Authors: Ineson Katherine M , Richardson Christopher S , Looney Caitlin E , Fuller Nathan W , Reichard Jonathan D 
Published: June 2023

Abstract
The patterns of recovery from injury or infection are not well studied in free-ranging animals. Bats that survive the fungal disease white-nose syndrome (WNS) often emerge from hibernation suffering from skin infections and wing damage. The extent of wing damage reflects physiological and immunological responses to WNS and may impact the ability of bats to fly, forage, and reproduce. Here, we built on previous studies of wing damage in both captive and free-ranging bats to better understand the patterns and extent of wing damage healing in little brown bats (Myotis lucifugus) post-hibernation. We quantified two main types of wing damage, black necrotic dots and white spots, and used the extent of damage to assign bats 1 of 6 wing damage scores. We found that the patterns of black dots and white spots on wing membranes of free-ranging bats aligned with the patterns observed in captive bats soon after emergence from hibernation. Black dot extent was highest at the beginning of the active season in May, while white spot extent peaked 3–4 weeks later. Our study also extends our knowledge of wing damage healing throughout the active season. Wing scores of bats recaptured within the summer decreased or stayed the same and &gt;95% had negligible signs of wing damage by August. We found that black dots were more indicative of disease status than other types of wing damage and could be consistently quantified in the field and from photographs by multiple observers. These results suggest that black dots and our wing damage scoring system can be used to better understand the patterns of post-hibernation healing in little brown bats impacted by WNS.
Predicting cancer incidence in regions without population-based cancer registries using mortality
Authors: Retegui Garazi , Etxeberria Jaione , Riebler Andrea , Ugarte María Dolores 
Published: June 2023

Abstract
Cancer incidence numbers are routinely recorded by national or regional population-based cancer registries (PBCRs). However, in most southern European countries, the local PBCRs cover only a fraction of the country. Therefore, national cancer incidence can be only obtained through estimation methods. In this paper, we predict incidence rates in areas without cancer registry using multivariate spatial models modelling jointly cancer incidence and mortality. To evaluate the proposal, we use cancer incidence and mortality data from all the German states. We also conduct a simulation study by mimicking the real case of Spain considering different scenarios depending on the similarity of spatial patterns between incidence and mortality, the levels of lethality, and varying the amount of incidence data available. The new proposal provides good interval estimates in regions without PBCRs and reduces the relative error in estimating national incidence compared to one of the most widely used methodologies.
Rare case of retroperitoneal mitotically active leiomyoma in a postmenopausal woman
Authors: Doita Susumu , Taniguchi Fumitaka , Mouri Kengo , Miyake Eiki , Hatono Minami , Kajioka Hiroki , Ogawa Toshihiro , Watanabe Megumi , Arata Takashi , Katsuda Kou , Tanakaya Kouji , Aoki Hideki 
Published: June 2023

Abstract
Leiomyomas are benign smooth muscle tumors, and retroperitoneal leiomyomas without coexisting uterine leiomyomas are extremely rare. Mitotically active leiomyomas, which are leiomyomas with increased mitotic activity, are rarely observed in postmenopausal women, except under the influence of exogenous hormones. This report presents a rare case of a retroperitoneal mitotically active leiomyoma in a postmenopausal woman. The patient presented with an abdominal mass and underwent surgical resection of the retroperitoneal tumor. Pathological examination revealed a mitotically active retroperitoneal leiomyoma with 31 mitotic figures per 10 high-power fields. The patient did not experience recurrence during the 2-year follow-up period. This case highlights the need to consider retroperitoneal mitotically active leiomyomas in postmenopausal women and suggests that myomectomy can prevent their recurrence.