bluuebunny/crossref_metadata_2025_split huggingface dataset:
Primary Aldosteronism and Drug Resistant Hypertension: A
“Chicken-Egg” Story
Authors: Lenzini L , Pintus G , Rossitto G , Seccia T M , Rossi G P 
Published: April 2023

AbstractDrug-resistant arterial hypertension (RH) is a major risk factor for
cardiovascular disease, often due to overlooked underlying causes.
Identification of such causes poses significant clinical challenges. In this
setting, primary aldosteronism (PA) is a frequent cause of RH and its prevalence
in RH patients is likely higher than 20%.The pathophysiological link between PA and the development and maintenance of RH
involves target organ damage and the cellular and extracellular effects of
aldosterone excess that promote pro-inflammatory and pro-fibrotic changes in the
kidney and vasculature.The feasibility of adrenal vein sampling in PA patients with RH, and the clinical
benefit achieved by adrenalectomy, further emphasize the need to implement
systematic screening for this common form of secondary hypertension in the
management of a high-risk population as RH patients.
We herein review the current knowledge of the factors that contribute to the RH
phenotype with a focus on PA and discuss the issues regarding the screening for
PA in this setting and the therapeutic approaches (surgical and medical) aimed
at resolving RH caused by PA.
Hybrid Palatoplasty: A Simplified DOZ (Double Opposing Z Plasty) with Palatal Myoplasty for Primary Palate Repair
Authors: Damalachervu Mukunda Reddy , Yellinedi Rajesh , Nuvvula Rambabu , A. Dharanipriya 
Published: April 2023

Abstract
Introduction Surgical techniques for soft palate repair aiming for zero velopharyngeal insufficiency (VPI) are still not achieved. Straight line closure of the soft palate by various techniques of intravelar veloplasty (IVVP) leads to higher incidence of VPI due to scar contracture. Furlow's Z plasty has long, narrow, thin mucosal flaps and mucomuscular flaps with malaligned muscle closure. We present a technique of “hybrid palatoplasty” which borrows from and adds to the existing methods, is robust, is easy to replicate, and results in normal speech consistently.
Aim (1) To design a technique of “hybrid palatoplasty”—combining double opposing Z (DOZ) plasty and IVVP, which is applicable to all types of cleft palate. (2) To evaluate the results of cleft palate children operated using the technique of “hybrid palatoplasty” from 2014 to 2015 in terms of surgical complications (fistulae and dehiscence) and incidence of VPI.
Methods Our procedure combines aspects of both DOZ and IVVP. It is simplified with design of smaller Z plasties. On one side, from the oral Z plasty muscle is dissected off and sutured to the nasal mucomuscular flap of the opposite side to complete the palatal sling. Oral Z plasty is purely mucosal and reverse of the nasal side. A total of 123 cases, operated below 5 years of age were followed up. Speech was assessed by direct evaluation and tele-evaluation.
Results A total of 123 cases, below 5 years of age, were operated between 2014 and 2016 with at least 5 years of follow-up. Note that 120 had normal speech, and 3 had VPI of which 2 were subsequently corrected and went on to develop normal speech.
Conclusion This novel “hybrid palatoplasty” is a simple technique with good speech outcome as it combines the principles of Z plasty and direct muscle repair with palatal sling formation.
SARS-CoV-2-Related Pediatric Encephalopathy with Biphasic Convulsions and Cortical Blindness: A Case Report
Authors: Shiraishi Yuriko , Tomari Kouki , Matsuoka Tsuyoshi , Numazawa Masaya , Matsuoka Takashi 
Published: April 2023

AbstractAcute encephalopathy with biphasic seizures and late reduced diffusion (AESD) is an encephalopathy syndrome that develops during the febrile phase of infection and is characterized by biphasic seizures and bright tree appearance (BTA) on imaging. In this study, we examined a 1-year-old child who was diagnosed with AESD caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. He had a fever for 2 days and was diagnosed with coronavirus disease 2019 on the day of consultation based on a positive antigen test for SARS-CoV-2. The seizures had stopped on arrival to hospital; however, symptoms of encephalopathy persisted. Despite being treated for acute encephalopathy with steroid pulse therapy, vitamins, and remdesivir, he had poor expressive language, and electroencephalography showed generalized slow waves. A repeat head magnetic resonance imaging showed BTA in the parietal and occipital lobes, and seizures recurred during hospital stay. He was also found to have cortical blindness. At the 4-month follow-up, the vision gradually improved and the hand movements recovered. SARS-CoV-2 infection can cause febrile convulsions, which can lead to the development of AESD. Furthermore, a subtype of AESD has occipital lobe predominant lesions that can cause visual impairment.
Asperisporium caricae (Speg.) Maubl.
Authors: CABI  , EPPO  
Published: April 2023

Abstract

A new distribution map is provided for Asperisporium caricae (Speg.) Maubl. Dothideomycetes: Mycosphaerellales: Mycosphaerellaceae. Host: papaya (
Carica papaya
).
Grapevine flavescence dorée phytoplasma
Authors: CABI  , EPPO  
Published: April 2023

Abstract

A new distribution map is provided for Grapevine flavescence dorée phytoplasma. Acholeplasmatales: Acholeplasmataceae: Phytoplasma: 16SrV(Elm yellows group). Main host: grapevine (
Vitis vinifera
).
Plectosphaerella melonis (Watanabe & Sato) Phillips, Carlucci & Raimondo
Authors: CABI  , EPPO  
Published: April 2023

Abstract

A new distribution map is provided for Plectosphaerella melonis (Watanabe & Sato) Phillips, Carlucci & Raimondo. Sordariomycetes: Phyllachorales: Plectosphaerellaceae. Hosts: melon (
Cucumis melo
), other Cucurbitaceae.
Armillaria luteobubalina Watling & Kile
Authors: CABI  , EPPO  
Published: April 2023

Abstract

A new distribution map is provided for Armillaria luteobubalina Watling & Kile. Agaricomycetes: Agaricales: Physalacriaceae. Main host: Eucalyptus spp.; spotted gum (
Corymbia spp.
).
Diaporthe amygdali (Delacr.) Udayanga, Crous & K.D. Hyde
Authors: CABI  , EPPO  
Published: April 2023

Abstract

A new distribution map is provided for Diaporthe amygdali (Delacr.) Udayanga, Crous & K.D. Hyde. Sordariomycetes: Diaporthales: Diaporthaceae. Hosts: Typically Prunus spp. especially peach (
Prunus persica
) and almond (
P. amygdalus
).
The longitudinal energy spread of ion beams extracted from an electron cyclotron resonance ion source
Authors: Angot J. , Tarvainen O. , Chauveau P. , Kosonen S.T. , Kalvas T. , Thuillier T. , Migliore M. , Maunoury L. 
Published: April 2023

Abstract
We present a study of factors affecting the energy spread of
ion beams extracted from a Charge Breeder Electron Cyclotron
Resonance Ion Source (CB-ECRIS). The comprehensive simulations,
supported by experiments with a Retarding Field Analyser (RFA),
reveal that the longitudinal and transverse energy spread of the
extracted beams are strongly affected by the electrostatic focusing
effects, namely the extraction geometry and plasma beam boundary, to
the extent that the electrostatic effects dominate over the magnetic
field induced rotation of the beam or the effect of plasma potential
and ion temperature. The dominance of the electrostatic focusing
effect over the magnetic field induced rotation complicates
parametric studies of the transverse emittance as a function of the
magnetic field strength, and comparison of emittance values obtained
with different ion sources having different extraction designs. Our
results demonstrate that the full ion beam energy spread, relevant
for the downstream accelerator, can be measured with the RFA only
when all ions are collected. On the contrary, studying the effect of
plasma properties (plasma potential and ion temperature) on the
longitudinal energy spread requires heavy collimation of the beam
accepting only ions near the symmetry axis of the beam for which the
electrostatic and magnetic effects are suppressed. As the extraction
system of the CB-ECRIS is similar to a conventional ECRIS, the
conclusions of the study can be generalised to apply for all high
charge state ECR ion sources. Finally, we present the results of
systematic plasma potential measurements of the Phoenix-type
CB-ECRIS at LPSC, varying the source potential, the microwave power
and the axial magnetic field srength. It was observed that the
plasma potential increases with the extraction magnetic field and
the microwave power.
RF design and frequency sensitivity analysis of a 1500 MHz passive third harmonic superconducting cavity for the SILF
Authors: Yuan N. , Ma W. , Sun Y. , Ge Y. , Zhang Z. , Wang C. , Zou Z. , Zou L. , Lu L. 
Published: April 2023

Abstract
To reduce Touschek scattering in the beam and extend the lifetime of the beam in the Shenzhen Innovation Light-source Facility (a fourth-generation light source), a 1500 MHz passive third harmonic system will be used. The present work is devoted to the RF design and frequency sensitivity analysis of the 1500 MHz passive third harmonic superconducting cavity, optimizing the RF parameters of the cavity, and giving a frequency scheme for the cavity in fabrication. The reliability of the cavity during operation is taken as the main goal for the optimization of the geometrical parameters, and its structural and RF parameters are obtained with E
peak/E
acc of 2.17, B
peak/E
acc of 5.12 mT/(MV/m) and G · R/Q of 25052 at 2 K. A pair of fluted beam pipes are used to propagate the higher order modes (HOMs) of the harmonic cavity, allowing a smooth transition of the first dipole mode to the absorber located at room temperature area. For the frequency sensitivity analysis, the frequency variations of the cavity in fabrication are obtained by multi-physics coupling simulation in the paper, which gives the target frequency of the cavity between welding and preloading. After electron beam welding (EBW), the resonant frequency of the cavity should be maintained at 1500.096 MHz, and the pre-tuning target frequency is 1497.456 MHz. The slow tuning range is ±400 kHz, the fast-tuning range is 600 Hz, and the maximum allowable tuning force is 15 kN.
Innovative process for precise grinding of optical free-form elements
Authors: Procháska František , Tomka David , Vavruška Petr , Paprčková Markéta , Melich Radek , Matoušek Ondřej , Lhomé Emilie 
Published: April 2023

Abstract
The aim of the presented article is to share experience gained throughout the course of two projects focused on precise grinding of a free-form glass optical element with the objective of achieving a surface shape error of less than approximately 10 μm PV before the subsequent polishing phases. Compared to spheres or aspheres machining, it is considerably more demanding, mainly due to the impossibility of using rotationally symmetric shape corrections. The developed and tested process combines a mechanical engineering approach based on the use of the current Computer Aided Design and Computer Aided Manufacturing software with their respective strengths and weaknesses and an optical engineering approach, for which the employment of CNC machines featuring precise control but low flexibility is typical. Therefore, attention is paid mainly to the description of particular process steps like CAD construction and CNC grinding step programming with regard to the necessary software and data handling, as well as the required parametrisation of the used machine equipment.
Arctic curves of the 20V model on a triangle
Authors: Di Francesco Philippe 
Published: April 2023

Abstract
We apply the Tangent Method of Colomo and Sportiello to predict the arctic curves of the Twenty Vertex model with specific domain wall boundary conditions on a triangle, in the Disordered phase, leading to a phase diagram with six types of frozen phases and one liquid one. The result relies on a relation to the Six Vertex model with domain wall boundary conditions and suitable weights, as a consequence of integrability. We also perform the exact refined enumeration of configurations.
Charging a quantum battery in a non-Markovian environment: a collisional model approach
Authors: Morrone Daniele , Rossi Matteo A C , Smirne Andrea , Genoni Marco G 
Published: April 2023

Abstract
We study the effect of non-Markovianity in the charging process of an open-system quantum battery. We employ a collisional model framework, where the environment is described by a discrete set of ancillary systems and memory effects in the dynamics can be introduced by allowing these ancillas to interact. We study in detail the behaviour of the steady-state ergotropy and the impact of the information backflow to the system on the different features characterizing the charging process. Remarkably, we find that there is a maximum value of the ergotropy achievable: this value can be obtained either in the presence of memoryless environment, but only in the large-loss limit, as derived in (Farina et al 2019 Phys. Rev. B 99 035421), or in the presence of an environment with memory also beyond the large-loss limit. In general, we show that the presence of an environment with memory allows us to generate steady-state ergotropy near to its maximum value for a much larger region in the parameter space and thus potentially in a shorter time. Relying on the geometrical measure of non-Markovianity, we show that in both the cases of an environment with and without memory the ergotropy maximum is obtained when the non-Markovianity of the dynamics of the battery is zero, possibly as the result of a non-trivial interplay between the memory effects induced by, respectively, the environment and the charger connected to the battery.
Extending the extended dynamic mode decomposition with latent observables: the latent EDMD framework
Authors: Ouala Said , Chapron Bertrand , Collard Fabrice , Gaultier Lucile , Fablet Ronan 
Published: April 2023

Abstract
Bernard O Koopman proposed an alternative view of dynamical systems based on linear operator theory, in which the time evolution of a dynamical system is analogous to the linear propagation of an infinite-dimensional vector of observables. In the last few years, several works have shown that finite-dimensional approximations of this operator can be extremely useful for several applications, such as prediction, control, and data assimilation. In particular, a Koopman representation of a dynamical system with a finite number of dimensions will avoid all the problems caused by nonlinearity in classical state-space models. In this work, the identification of finite-dimensional approximations of the Koopman operator and its associated observables is expressed through the inversion of an unknown augmented linear dynamical system. The proposed framework can be regarded as an extended dynamical mode decomposition that uses a collection of latent observables. The use of a latent dictionary applies to a large class of dynamical regimes, and it provides new means for deriving appropriate finite-dimensional linear approximations to high-dimensional nonlinear systems.
Convergence analysis of Nédélec finite element approximations for a stationary Maxwell’s system
Authors: Tran Quyen 
Published: April 2023

In this paper we analyze the Maxwell system

{

∇
×

(

σ

−
1

(

x

)
∇
×

E

(

x

)
)

a
m
p
;
=

ϵ
(

x

)

u

(

x

)
,

x

∈
Ω

∇
⋅
(
ϵ
(

x

)

E

(

x

)
)

a
m
p
;
=

ρ
(

x

)
,

x
x
x
i

x

∈
Ω

E

(

x

)
×

n

→

(

x

)

a
m
p
;
=

0

,

x
x
x
x
x
x

x

∈
∂
Ω

∇
⋅

(
ϵ
(

x

)

u

(

x

)
)

a
m
p
;
=

0
,

x
x
x
x
x
x

x

∈
Ω

\begin{equation*} \begin {cases} \nabla \times \left (\sigma ^{-1}(\mathbf {x} )\nabla \times \mathbf {E}(\mathbf {x} )\right )&=~ \epsilon (\mathbf {x} ) \mathbf {u}(\mathbf {x}), \quad \mathbf {x} \in \Omega \\ \nabla \cdot (\epsilon (\mathbf {x} ) \mathbf {E}(\mathbf {x} )) &=~ \rho (\mathbf {x} ), \quad \phantom {xxxi} \mathbf {x} \in \Omega \\ \mathbf {E}(\mathbf {x} )\times \vec {\mathbf {n}}(\mathbf {x}) &=~ \mathbf {0}, \quad \phantom {xxxxxx} \mathbf {x} \in \partial \Omega \\ \nabla \cdot \left ( \epsilon (\mathbf {x} ) \mathbf {u}(\mathbf {x})\right ) &=~0, \quad \phantom {xxxxxx}\mathbf {x} \in \Omega \end{cases} \end{equation*}

with the Nédélec finite elements. We show the convergence of the finite element approximations as well as establish their error bounds.
A New Legal Form for Social Enterprises in Asia
Authors: Lim Ernest 
Published: April 2023

Abstract
This Article argues that there should be a new legal form for social enterprises in Asia that takes into account the distinctive contexts within which different types of social enterprises operate in the different Asian jurisdictions. In order to understand and evaluate social enterprise law, this Article advances an analytic framework consisting of (i) corporate purpose; (ii) directors’ duties; (iii) decision-making powers; (iv) reporting and certification; and (v) distribution of dividends, assets, and tax benefits. Using the four leading common law jurisdictions (Singapore, Hong Kong, Malaysia, and India) as a case study, the Article challenges the dominant assumption that the existing legal forms in Asia are adequate and appropriate to achieving the aims of social enterprises in Asia. It also critiques the legal forms for social enterprises in the United Kingdom and the United States, and finds them unsuitable for adoption by the Asian jurisdictions.
Behavioral and Personal Characteristics Associated With Risk of SARS-CoV-2 Infection in a Spanish University Cohort
Authors: Amer Fares , Gil-Conesa Mario , Carlos Silvia , Ariño Arturo H , Carmona-Torre Francisco , Martínez-González Miguel A , Fernandez-Montero Alejandro 
Published: April 2023

Abstract
The aim of this study was to analyze the life habits and personal factors associated with increased severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) risk in a university environment with in-person lectures during the coronavirus disease 2019 (COVID-19) pandemic. To our knowledge, there are no previous longitudinal studies that have analyzed associations of behavioral and personal factors with the risk of SARS-CoV-2 infection on an entire university population. A cohort study was conducted in the 3 campuses of the University of Navarra between August 24, 2020, and May 30, 2021, including 14,496 students and employees; the final sample included 10,959. Descriptive and multivariate-adjusted models were fitted using Cox regression. A total of 1,032 (9.4%) participants were diagnosed with COVID-19 (879 students and 153 employees), almost 50% living with their families. COVID-19 was associated with living in college or residence (hazard ratio (HR) = 1.96, 95% CI: 1.45, 2.64), motor transportation (HR = 1.35, 95% CI: 1.14, 1.61), South American origin (HR = 1.43, 95% CI: 1.20, 1.72), and belonging to Madrid’s campus (HR = 3.11, 95% CI: 2.47, 3.92). International students, especially from Latin America, mostly lived in university apartments or shared flats and cohabited with 4–11 people. Living in a big city (Madrid), was a significant risk factor.
Stimulation of non-motor subthalamic nucleus impairs selective response inhibition via prefrontal connectivity
Authors: Waldthaler Josefine , Sperlich Alexander , Stüssel Charlotte , Steidel Kenan , Timmermann Lars , Pedrosa David J 
Published: April 2023

AbstractGiven the inconsistent results in the past, there is an ongoing debate whether and how deep brain stimulation in the subthalamic nucleus modifies cognitive control processes like response inhibition in persons with Parkinson’s disease. In this study, we examined how the location of the stimulation volume within the subthalamic nucleus affects the performance in an antisaccade task but also how its structural connectivity is related to response inhibition. Antisaccade error rates and latencies were collected in 14 participants on and off deep brain stimulation in a randomized order. Stimulation volumes were computed based on patient-specific lead localizations using preoperative MRI and postoperative CT scans. Structural connectivity of the stimulation volumes with pre-defined cortical oculomotor control regions as well as whole-brain connectivity was estimated using a normative connectome. We showed that the detrimental effect of deep brain stimulation on response inhibition, measured as antisaccade error rate, depended upon the magnitude of the intersection of volumes of activated tissue with the non-motor subregion of the subthalamic nucleus and on its structural connectivity with regions of the prefrontal oculomotor network including bilateral frontal eye fields and right anterior cingulate cortex. Our results corroborate previous recommendations for avoidance of stimulation in the ventromedial non-motor subregion of the subthalamic nucleus which connects to the prefrontal cortex to prevent stimulation-induced impulsivity. Furthermore, antisaccades were initiated faster with deep brain stimulation when the stimulation volume was connected to fibres passing the subthalamic nucleus laterally and projecting onto the prefrontal cortex, indicating that improvement of voluntary saccade generation with deep brain stimulation may be an off-target effect driven by stimulation of corticotectal fibres directly projecting from the frontal and supplementary eye fields onto brainstem gaze control areas. Taken together, these findings could help implement individualized circuit-based deep brain stimulation strategies that avoid impulsive side effects while improving voluntary oculomotor control.
Prognostic echocardiographic findings in patients supported with venoarterial extracorporeal membrane oxygenation for cardiogenic shock
Authors: Siriwardena Maithri , Brahmbhatt Darshan H , Douflé Ghislaine , Fan Eddy , Billia Filio 
Published: April 2023

Abstract

Aims
Echocardiography is critical in the management of patients supported with veno-arterial extracorporeal membrane oxygenation (V-A ECMO). This study aimed to identify the incidence of critical echocardiographic findings and determine their prognostic significance.

Methods and results
All available echocardiograms, hemodynamic variables and outcomes of patients with CS supported with V-A in the period of 2011-2018 at the Toronto General Hospital were retrospectively reviewed. Critical echocardiographic findings were defined as minimal to no left ventricular (LV) ejection, the presence of intra-cardiac clot, significant pericardial effusion and malpositioning of ECMO cannulae. 130 patients were included in this study with in-hospital mortality of 58.5%. Critical findings were most often seen in the first echocardiogram (42/121; 35%). The incidence of critical findings in the first echocardiogram was minimal to no LV ejection in 28 patients (23%), intracardiac thromboses in 8 patients (6.6%), tamponade in 5 patients (4%) and malpositioned cannulae in 1 patient (0.8%). Presence of a critical finding in the first study was associated with an odds ratio for in-hospital mortality of 2.32 (95% CI 1.01-5.06, P = 0.011).

Conclusion
The initial echocardiogram was most likely to demonstrate a critical finding of which the most common was minimal to no LV ejection. Critical echocardiographic findings carried prognostic significance for in-hospital mortality.