bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Self‐Reconfigured, Dual‐Layered Artificial Interphase Toward High‐Current‐Density Quasi‐Solid‐State Lithium Metal Batteries
Authors: Guo Jun‐Chen , Tan Shuang‐Jie , Zhang Chao‐Hui , Wang Wen‐Peng , Zhao Yao , Wang Fuyi , Zhang Xu‐Sheng , Wen Rui , Zhang Ying , Fan Min , Xin Sen , Zhang Juan , Guo Yu‐Guo 
Published: March 2023

AbstractThe uncontrollable dendrite growth and unstable solid electrolyte interphase have long plagued the practical application of Li metal batteries. Herein, a dual‐layered artificial interphase LiF/LiBO–Ag is demonstrated that is simultaneously reconfigured via an electrochemical process to stabilize the lithium anode. This dual‐layered interphase consists of a heterogeneous LiF/LiBO glassy top layer with ultrafast Li‐ion conductivity and lithiophilic Li–Ag alloy bottom layer, which synergistically regulates the dendrite‐free Li deposition, even at high current densities. As a result, Li||Li symmetric cells with LiF/LiBO–Ag interphase achieve an ultralong lifespan (4500 h) at an ultrahigh current density and area capacity (20 mA cm−2, 20 mAh cm−2). LiF/LiBO–Ag@Li anodes are successfully applied in quasi‐solid‐state batteries, showing excellent cycling performances in symmetric cells (8 mA cm−2, 8 mAh cm−2, 5000 h) and full cells. Furthermore, a practical quasi‐solid‐state pouch cell coupling with a high‐nickel cathode exhibits stable cycling with a capacity retention of over 91% after 60 cycles at 0.5 C, which is comparable or even better than that in liquid‐state pouch cells. Additionally, a high‐energy‐density quasi‐solid‐state pouch cell (10.75 Ah, 448.7 Wh kg−1) is successfully accomplished. This well‐orchestrated interphase design provides new guidance in engineering highly stable interphase toward practical high‐energy‐density lithium metal batteries.
Lightweight All Graphene‐Based Two‐Phase Heat Transport Devices
Authors: Zheng Feiyu , Shen Qingchen , Wang Zhiying , Cheng Weizheng , Wang Ruitong , Fang Cheng , Chu Ben , Tao Jinran , Zhang Wanli , Tao Peng , Song Chengyi , Shang Wen , Fu Benwei , Deng Tao 
Published: March 2023

AbstractGraphene‐based composites show great potential in the development of lightweight functional devices and systems, and polymers are usually used as binders to enhance the mechanical properties of these composites. Due to the low thermal conductivity of the polymer and the high inherent interfacial thermal resistance between polymer and graphene, however, the developed devices and systems generally possess low thermal conductivity, which seriously limits their further thermal‐related applications. Here, a lightweight two‐phase heat transport device (TPHTD) based on a vapor‐liquid phase transition‐based heat transfer by using a graphene‐based composite material as the casing is generated. The graphene‐based TPHTD has high thermal conductivity of up to 1408 W (mK)−1and realizes ultra‐high specific thermal conductivity of ≈5600 W (mKg)−1. This graphene‐based device with lightweight and high heat transfer capacity offers new opportunities for efficient thermal management of compact, portable, or wearable electronic and power systems.
Mitochondrial TSPO Promotes Hepatocellular Carcinoma Progression through Ferroptosis Inhibition and Immune Evasion
Authors: Zhang Deguo , Man Da , Lu Jiahua , Jiang Yifan , Ding Bo , Su Rong , Tong Rongliang , Chen Junru , Yang Beng , Zheng Shusen , Chen Diyu , Wu Jian 
Published: March 2023

AbstractHepatocellular carcinoma (HCC) is one of the most common malignancies with poor prognosis, and novel treatment strategies are urgently needed. Mitochondria are key regulators of cellular homeostasis and potential targets for tumor therapy. Here, the role of mitochondrial translocator protein (TSPO) in the regulation of ferroptosis and antitumor immunity is investigated and the potential therapeutic implications for HCC are assessed. TSPO is highly expressed in HCC and associated with poor prognosis. Gain‐ and loss‐of‐function experiments present that TSPO promotes HCC cell growth, migration, and invasion in vitro and in vivo. In addition, TSPO inhibits ferroptosis in HCC cells via enhancing the Nrf2‐dependent antioxidant defense system. Mechanistically, TSPO directly interacts with P62 and interferes with autophagy, leading to the accumulation of P62. The P62 accumulation competes with KEAP1, preventing it from targeting Nrf2 for proteasomal degradation. Furthermore, TSPO promotes HCC immune escape by upregulating PD‐L1 expression through Nrf2‐mediated transcription. Notably, TSPO inhibitor PK11195 combines with anti‐PD‐1 antibody showing a synergistic anti‐tumor effect in a mouse model. Overall, the results demonstrated that mitochondrial TSPO promotes HCC progression by inhibiting ferroptosis and antitumor immunity. Targeting TSPO can be a promising new strategy for HCC treatment.
Of women and land: How gender affects successions and transfers of Iowa farms
Authors: Liu Qing , Maule Beatrice , Zhang Wendong 
Published: March 2023

AbstractUsing 589 responses to the 2019 Iowa Farm Transfer Survey, we examine factors in farm successor choices among Iowa farmers with a focus on female successors and landowners. Among those with identified successors, 57% chose sons and 8% chose daughters. We find a 12.4% probability a female farmer will choose a daughter, but only 5.9% for a male farmer. Agriculture experience increases the probability of choosing a daughter from 5.4% to 20.7% and from 36.3% to 65.2% for a son. Our paper reveals striking evidence of gender imbalance in farm succession, transfer, and inheritance decisions of US farms.
Access toward steroid skeleton and its derivatives via copper‐catalyzed intramolecular cyclization: A short synthesis of estradiol and estrone
Authors: Liaba Niaz , Lee Junseong , Oh Chang Ho 
Published: March 2023

AbstractA practical and efficient approach leading to [6,6,6,5] tetracyclic fused ring steroid skeletons (8 a–i) has been designed through copper catalyzed intramolecular [4+2] cycloaddition reaction of enyne‐carbonyl substrates (7 a–i). The compound 8 a having OMe group at aromatic ring was further utilized to synthesize estradiol and Estrone.
11C‐Cyanation of Aryl Fluorides via Nickel and Lithium Chloride‐Mediated C−F Bond Activation
Authors: Zhang Zhouen , Niwa Takashi , Watanabe Kenji , Hosoya Takamitsu 
Published: March 2023

AbstractAryl fluorides are expected to be useful as radiolabeling precursors due to their chemical stability and ready availability. However, direct radiolabeling via carbon‐fluorine (C−F) bond cleavage is a challenging issue due to its significant inertness. Herein, we report a two‐phase radiosynthetic method for the ipso‐11C‐cyanation of aryl fluorides to obtain [11C]aryl nitriles via nickel‐mediated C−F bond activation. We also established a practical protocol that avoids the use of a glovebox, except for the initial preparation of a nickel/phosphine mixture, rendering the method applicable for general PET centers. This method enabled the efficient synthesis of diverse [11C]aryl nitriles from the corresponding aryl fluorides, including pharmaceutical drugs. Stoichiometric reactions and theoretical studies indicated a significant promotion effect of lithium chloride on the oxidative addition, affording an aryl(chloro)nickel(II) complex, which serves as a precursor for rapid 11C‐cyanation.
Long‐term persistence of large dugong groups in a conservation hotspot around Hawar Island, Kingdom of Bahrain
Authors: Khamis Abdulqader , Abdulla Ameer , D'Souza Elrika , Kelkar Nachiket , Arthur Rohan , Al Khalifa Ebrahim , Bader Hani , Alcoverro Teresa 
Published: March 2023

Abstract

Predictable aggregations of large marine mammals are valuable conservation targets, but aggregated populations can also be exposed to site‐level threats.
The globally vulnerable Dugong dugon has a wide distribution but is found in large numbers mainly in Australia and the Arabian Gulf. Though Australian dugong populations are well studied, much less is known of the dugongs in the Arabian Gulf.
The spatial and temporal persistence of dugongs around Bahrain, with a focus on large dugong groups (>50 dugongs), was determined using an occupancy modelling framework supported by historical records, structured interviews, citizen science network reports, and small‐scale boat and unmanned aerial vehicle surveys.
Historical records and current distributional studies confirmed that large dugong groups have been reliably sighted around Hawar Island (Bahrain) since at least 1986, forming large, clumped groups that persist almost year round. The largest recorded so far in the world, these fluid groups (maximum of ~700 dugongs) account for ~60% of the dugongs found in Bahrain and ~12% of all dugongs in the Arabian Gulf.
The delineated occupancy core area of large dugong groups (~145 km2) straddles the Bahrain–Qatar border, reflecting the transboundary nature of these groups.
Careful management of human‐induced stressors (in particular, fishing, boating, and coastal development) combined with regular monitoring of Hawar Island's large dugong groups and their seagrass habitat is critical to safeguard this globally important population.
The effectiveness of any conservation management is predicated on strengthening cooperation among all range states in the Arabian Gulf. A key recommendation of this study is to establish a regional network of marine protected areas encompassing core aggregation sites for dugongs, particularly the Hawar Islands in Bahrain, the north‐western waters of Qatar, Marawah Island in the United Arab Emirates in addition to the shallow waters between Saudi Arabia, Qatar, and United Arab Emirates.
Xenorhinos bhatnagari sp. nov., a new, nasal‐emitting trident bat (Rhinonycteridae, Rhinolophoidea) from early Miocene forests in northern Australia
Authors: Hand Suzanne J. , Archer Michael , Gillespie Anna , Myers Troy 
Published: March 2023

AbstractA new Old World trident bat (Rhinonycteridae) is described from an early Miocene cave deposit in the Riversleigh World Heritage Area, northwestern Queensland, Australia. Living rhinonycterids comprise a small family of insect‐eating, nasal‐emitting rhinolophoid bats from Africa, Madagascar, Seychelles, the Middle East, and northern Australia. The new fossil species is one of at least 12 rhinonycterid species known from the Oligo‐Miocene cave deposits at Riversleigh. We refer the new species to the genus Xenorhinos (Hand, Journal of Vertebrate Paleontology, 18, 430–439, 1998a) because it shares a number of unusual cranial features with the type and only other species of the genus, X. halli, including a broad rostrum, very wide interorbital region, pronounced ventral flexion of the rostrum, very constricted sphenoidal bridge, and, within the nasal fossa, reduced bony division, and relatively well developed turbinals. Xenorhinos species lived in northern Australia during the global Miocene Climatic Optimum, in closed wet forests, unlike the drier habitats that trident bats largely inhabit today. Our phylogenetic analysis suggests that more than one dispersal event gave rise to the Australian rhinonycterid radiation, with two lineages having sister‐group relationships with non‐Australian taxa.
Combined physicochemical and functional assessment of pertuzumab integrity supports extended in‐use stability
Authors: Jirschitzka Sven , Längle Daniel , Lück Hendrik , Schade Dennis , Kunze Thomas 
Published: March 2023

AbstractPertuzumab (Perjeta®) is a monoclonal antibody approved for the treatment of HER2‐positive breast cancer. Before treatment, the concentrate must be diluted to obtain the ready‐to‐use infusion solution. Data on the storage stabilities of these preparations are lacking but important for all healthcare professionals in the area of outpatient chemotherapy. The aim of this study was to investigate the storage stability of the ready‐to‐use infusion bags and the concentrates from once‐opened vials over a period of up to 42 days. For a comprehensive and unambiguous assessment of pertuzumab's integrity, a panel of orthogonal analytical methods was employed, including a newly established mass spectrometry‐based peptide mapping procedure along with a reporter gene assay for monitoring cellular bioactivity. The herein presented data showed that the ready‐to‐use infusion solutions stored at 4 ± 2°C and at 20 ± 3°C without light protection, as well as the undiluted Perjeta® concentrates stored at 4 ± 2°C, were physicochemically stable and biologically active for 28 days. These results might eventually allow for infusion preparations in advance, thus improving the quality of patient care as well as the economic usage of pertuzumab.
π‐Extended BTD Derivatives: Synthesis, Photophysical Properties, and Applications in Biological Systems Imaging for Discriminating Living and Dead Cells
Authors: Li Cong‐Cong , Cao Jiaxin , Wang Lin , Ji Xingxiang , Xu Yanjun , Wang Jian‐Yong 
Published: March 2023

AbstractHere, π‐Extended BTD derivatives were successfully synthesized by Heck coupling reaction, which exhibited the the advantages of simplicity and efficiency, wild substrate scope, easily available substrates and high yield. The fluorescent probe PEG‐BTDAr targeting LDs was successfully prepared by the nucleophilic substitution reaction between the Heck coupling reaction product 3 h and Amino polyethylene glycol monomethyl ether (Mn=2000). PEG‐BTDAr exhibited the advantages of high selectivity, good stability and pH resistance. The use of PEG as a substrate gave PEG‐BTDAr good biocompatibility. It was worth mentioning that PEG‐BTDAr could not only track LDs in cells under different physiological conditions, but also distinguish between living and dead cells in biological systems.
Analysis of barriers affecting circular economy adoption in food supply chain: A strategic perspective
Authors: Sonar Harshad , Ghag Nikhil , Kharde Yashomandira , Ghosh Shriya 
Published: March 2023

AbstractThe circular economy (CE) is specifically transforming the linear food supply chains (FSCs), which attracted a lot of interest from practitioners and researchers in order to address the global difficulties facing the FSCs today. However, there has not been much discussion of implementing CE activities in literature, especially in the FSCs. The purpose of this study is to identify the barriers for implementing CE in the FSC. Barriers are identified from past academic literature and are finalized based on the fuzzy‐Delphi method. Nine experts provided their opinions to develop the contextual relationship between identified barriers using the DEMATEL with Neutrosophic set theory. As per the findings, top management commitment is crucial for the successful adoption of CE throughout the FSC followed by poor corporate social responsibility. The novelty lies in identification of the barriers for implementing CE in FSC using Neutrosophic theory. This study will assist professionals in developing advantageous ways for adopting the CE to gain sustained competitive advantage in the FSC. Managers and planners can better understand and implement CE strategies in the FSC. The FSC can become more sustainable in a number of ways by using the CE concepts.
Establishment and validation of systematic prognostic nomograms in patients over 60 years of age with osteosarcoma: A multicenter external verification study
Authors: Shao Zhuce , Li JiaChen , Liu Ze , Bi Shuxiong 
Published: March 2023

AbstractBackgroundThe aim of this study was to develop and validate systematic nomograms to predict cancer specific survival (CSS) and overall survival (OS) in osteosarcoma patients aged over 60 years.MethodsWe used data from the Surveillance, Epidemiology, and End Results (SEER) database and identified 982 patients with osteosarcoma over 60 years of age diagnosed between 2004 and 2015. Overall, 306 patients met the requirements for the training group. Next, we enrolled 56 patients who met the study requirements from multiple medical centers as the external validation group to validate and analyze our model. We collected all available variables and finally selected eight that were statistically associated with CSS and OS through Cox regression analysis. Integrating the identified variables, we constructed 3‐ and 5‐year OS and CSS nomograms, respectively, which were further evaluated by calculating the C‐index. A calibration curve was used to evaluate the accuracy of the model. Receiver operating characteristic (ROC) curves measured the predictive capacity of the nomograms. The Kaplan–Meier analysis was used for all patient‐based variables to explore the influence of various factors on patient survival. Finally, a decision curve analysis (DCA) curve was used to analyze whether our model would be suitable for application in clinical practice.ResultsCox regression analysis of clinical variables identified age, sex, marital status, tumor grade, tumor laterality, tumor size, M‐stage, and surgical treatment as prognostic factors. Nomograms showed good predictive capacity for OS and CSS. We calculated that the C‐index of the OS nomogram of the training population was 0.827 (95% CI 0.778–0.876), while that of the CSS nomogram was 0.722 (95% CI 0.665–0.779). The C‐index of the OS nomogram evaluated on the external validation population was 0.716 (95% CI 0.575–0.857), while that of the CSS nomogram was 0.642 (95% CI 0.50–0.788). Furthermore, the calibration curve of our prediction models indicated the nomograms could accurately predict patient outcome.ConclusionsThe constructed nomogram is a useful tool for accurately predicting OS and CSS at 3 and 5 years for patients over 60 years of age with osteosarcoma and can assist clinicians in making appropriate decisions in practice.
A case of acute myelomonocytic leukemia morphologically mimicking lymphoblastic leukemia
Authors: Ni Sao‐Chih , Yao Chi‐Yuan , Tien Feng‐Ming , Lin Chien‐Chin 
Published: March 2023

AbstractWe present the case of a 70‐year‐old man diagnosed with acute myelomonocytic leukemia, albeit that his leukemic blasts at initial presentation had scant cytoplasm, inconspicuous cytoplasmic granules, and morphologically mimicked lymphoblasts. We would like to raise the recognition that acute myelomonocytic leukemia can actually present with atypical blast morphology.
Microaggressions, mentoring, and connectedness: Doctoral students’ experiences in counselor education
Authors: Vaishnav Shreya , Wester Kelly L. 
Published: March 2023

AbstractThis descriptive, correlational research study examined the prevalence of racial microaggressions among doctoral students of color in counselor education, and the relationships between experiences of racial microaggressions, relational mentoring, and social connectedness. Implications and future directions are provided based on the results.
Synthesis of Activated Carbon from Agricultural Wastes and Its Application in Adsorption of Dyes
Authors: Hamad Kareem H. , El-Sayed Amal M. , Mohamed Ahmed G. , Mostafa Ahmed H. , Deeb Nayera M. El , Tedawy Ahmed H. , Leithy Ali G. El , Abdelhamid Mostafa F. , Tawab Sayed Abdel , Aly Sohair T. 
Published: March 2023

AbstractActivated carbon (AC) is one of the most used materials in dye removal that can be synthesized using different agricultural wastes. In this work, the effects of waste type and pyrolysis temperature were investigated. Corn cob and wheat straw were used for preparation of activated carbon by applying 10 % H3PO4 as an activating agent, followed by pyrolysis at 400 or 500 °C and then thermal activation at 800 °C for 10 minutes. Elemental analysis, acid soluble matter, ash content, and calorific value were measured for the prepared samples of AC. Finally, the product was applied for adsorption of Congo Red and Nile Blue dyes from wastewater and the maximum adsorption capacity was found to be 99.56 and 85.23 mg g−1, respectively using a corn cob sample activated at 500 °C.
Highly Efficient Wavelength‐Tunable Circularly Polarized Luminescence Film Constructed by Responsive Chiral Aggregation‐induced Emission Luminophore
Authors: Luo Zhi‐Wang , Huang Ao , Deng Yuan , Huang Jiang , Bu Zhen‐Qing , Xie He‐Lou 
Published: March 2023

AbstractKey Lab of Environment‐friendly Chemistry and Circularly polarized luminescent (CPL) materials with multitudinous inherent advantages shows extensive application. In this work, we prepare a kind of highly efficient wavelength‐tunable CPL free‐standing films by responsive chiral aggregation‐induced emission mesogen. Firstly, the pyridine‐functionalized tetraphenylethene monomer (MPy) is designed and synthesized. Then, the different ration of the monomer MPy mixed with the liquid crystal (LC) reactive monomer (LC242) to fabricate a free‐standing film by photopolymerization. The obtained film presents efficient CPL with a constant luminescence asymmetry factor (glum) of +0.75, as well as sensitive wavelength tunability. Finally, this wavelength‐tunable CPL film with both fluorescence and CPL modes is successfully applied in anti‐counterfeiting and information encryption. This work provides a simple way to construct CPL apparatus with adjustable luminescence wavelength and high glum.
Bis[1]benzothieno[1,4]thiaborins as a Platform for BODIPY Singlet Oxygen Photosensitizers
Authors: Marek‐Urban Paulina H. , Urbanowicz Karolina A. , Wrochna Karolina , Pander Piotr , Blacha‐Grzechnik Agata , Hauer Simone T. , Berens Henning R. V. , Woźniak Krzysztof , Müller Thomas J. J. , Durka Krzysztof 
Published: March 2023

AbstractA synthetic approach to two regioisomeric π‐electron extended [1,4]thiaborins annulated with two benzothiophene units has been developed. The central thiaborin rings of the boracycles obtained exhibit different electronic properties; this is reflected in their different aromatic characters, boron Lewis acidity and UV‐vis spectroscopic behavior. Thiaborins were converted to boron dipyrromethene (BODIPY) complexes. Their emission spectra exhibit two distinct bands resulting from 1LE and 1CT transitions. Strong near‐infrared phosphorescence in Zeonex thin films at 77 K indicates efficient intersystem crossing and the formation of triplet states. Separation of HOMO and LUMO orbitals between boracyclic and BODIPY moieties facilitates electron transfer to a 1CT state followed by a transition to the 3LE triplet state located on the ligand. These unique properties of spiro thiaborin‐BODIPY complexes were explored for their application as singlet‐oxygen photosensitizers. They show excellent photocatalytic performance with singlet oxygen quantum yields reaching 77 % and full conversion of the model organic substrate achieved after 1.5 h with only 0.05 % mol catalyst load.