bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fluorescent Probes for Detection of Environmental Contaminants (NACs & VOCs): Probe Design from a Supramolecular Perspective
Authors: Basak Megha , Das Gopal 
Published: July 2023

AbstractFresh air and clean water are essential constituents for the human population as well as for fauna and flora. Owing to the extreme toxicity of NACs and VOCs in physiological systems and their widespread presence in the environment, serious mitigation is required. The innovation of chemosensors for these two types of harmful organic contaminants (NACs i. e., nitroaromatics, and VOCs i. e., volatile organic compounds) have unfolded as a key research topic in recent decades, garnering a lot of attention due to their environmental, industrial and biological importance. In recent years, there has been a significant amount of research on both NACs and VOCs chemosensors. This Review article has recapitulated the latest development of fluorescent chemosensors especially small molecular frameworks from 2015 to 2022, for NACs and VOCs which has been discussed individually. In addition, the detection of NACs and VOCs on multiple platforms with a special focus on their mechanistic exploration, as well as their probable applications in natural water body specimens, vapor phase detection, and paper strip analysis have also been discussed.
Big Data and Machine Learning: What Is It and Can We Use It for 4R Nutrient Management?
Authors: Nigon Leanna Leverich 
Published: July 2023

AbstractBig data and machine learning have the potential to transform agriculture and 4R nutrient management practices. The integration of these technologies empowers farmers to adapt to variable conditions, optimize applications, and minimize environmental impact. While challenges such as data quality must be addressed, the future prospects are promising. Earn 1 CEU in Nutrient Management by reading this article and taking the quiz at https://web.sciencesocieties.org/Learning‐Center/Courses.
Mechanochemistry toward Organic “Salt” via Integer‐Charge‐Transfer Cocrystal Strategy for Rapid, Efficient, and Scalable Near‐Infrared Photothermal Conversion
Authors: Chen Shun‐Li , Zhang Meng‐Meng , Chen Jiecheng , Wen Xinyi , Chen Wenbin , Li Jiayu , Chen Ye‐Tao , Xiao Yonghong , Liu Huifen , Tan Qianqian , Zhu Tangjun , Ye Bowei , Yan Jiajun , Huang Yihang , Li Jie , Ni Shaofei , Dang Li , Li Ming‐De 
Published: July 2023

AbstractInvited for this month′s cover is the group of Shun‐Li Chen and Ming‐De Li at the Shantou University. The image shows that one electron can be transferred easily from donor to acceptor unit to obtain integer‐charge‐transfer cocrystals for realizing high‐efficient solar‐harvesting and photothermal conversion. The Research Article itself is available at 10.1002/cssc.202300644.
Artificial intelligence enabled Luong Attention and Hosmer Lemeshow Regression Window‐based attack detection in 6G
Authors: Bhuvaneshwari B. , Balusamy Balamurugan , Dhanaraj Rajesh Kumar , Ravi Vinayakumar 
Published: July 2023

SummaryRegardless of the developments of networking and communication technologies, security is without exception a predominant feature to ensure network reliability. The future sixth‐generation (6G) network is anticipated to be carried out with artificial intelligence (AI) powered communication via machine learning (ML), post‐quantum cryptography, and so on. AI‐powered communication has been in recent years utilized in enhancing network traffic performance with respect to resource management, optimal frequency spectrum design, security, and latency. The studies of modern wireless communications and anticipated features of 6G networks revealed a prerequisite for designing a trustworthy attack detection mechanism. In this work, a method called, Luong Attention and Hosmer Lemeshow Regression Window‐based (LA‐HLRW) attack detection in 6G is proposed. Initially, with the raw Botnet Attack dataset obtained as input, preprocessing is performed to normalize network traffic features. Next, the dimensionality of network traffic feature of large‐scale network traffic data is reduced using the Luong Attention integrated with Long Short Term Memory (LSTM)‐based Feature extraction model. Finally, with the objective of classifying network traffic samples for attack detection in 6G, we analyze the low dimensional network traffic feature set produced by Luong Attention integrated with LSTM using the Hosmer Lemeshow Logistic Regression Window‐based Attack Detection model. Extensive experiments are performed with the Botnet Attack dataset to validate the efficiency of the proposed LA‐HLRW method by using different parameters such as attack detection accuracy, attack detection time, precision, and recall. The overall analysis of proposed LA‐HLRW results significantly reduced the attack detection time by 24%, and additionally improved attack detection accuracy, precision, and recall by 5%, 5%, and 6% as compared to existing attack detection methods respectively.
Systematic review and meta‐analysis of the effects of foot and ankle physical therapy, including mobilisations and exercises, in people with diabetic peripheral neuropathy on range of motion, peak plantar pressures and balance
Authors: Lepesis Vasileios , Marsden Jonathan , Rickard Alec , Latour Jos M. , Paton Joanne 
Published: July 2023

AbstractTo evaluate the effects of foot and ankle physical therapy on ankle and first metatarsophalangeal joint range of motion (ROM), peak plantar pressures (PPPs) and balance in people with diabetes. MEDLINE, EBSCO, Cochrane Database of Systematic Reviews, Joanna Briggs Institute Database of Systematic Reviews, PROSPERO, EThOS, Web of Science and Google Scholar were searched in April 2022. Randomised Controlled Trials (RCT), quasi‐experimental, pre‐post experimental design and prospective cohort studies were included. Participants were people with diabetes, neuropathy and joint stiffness. Interventions included physical therapy such as mobilisations, ROM exercises and stretches. Outcome measures focused on ROM, PPPs and balance. Methodological quality was assessed with Critical Appraisal Skills Programme RCT and Risk‐of‐Bias 2 tool. Meta‐analyses used random‐effects models and data was analysed using the inverse variance method. In total, 9 studies were included. Across all studies, participant characteristics were similar; however, type and exercise dosage varied greatly. Meta‐analysis was performed with four studies. Meta‐analysis showed significant effects of combined exercise interventions in increasing total ankle ROM (3 studies: MD, 1.76; 95% CI, 0.78–2.74; p = 0; I2 = 0%); and reducing PPPs in the forefoot area (3 studies; MD, −23.34; 95% CI, −59.80 to 13.13; p = 0.21, I2 = 51%). Combined exercise interventions can increase ROM in the ankle and reduce PPPs in the forefoot. Standardisation of exercise programmes with or without the addition of mobilisations in the foot and ankle joints needs further research.
A difference in larval mosquito size allows a biocontrol agent to target the invasive species
Authors: Russell Marie C 
Published: July 2023

AbstractAs the global temperature rises in the coming decades, Aedes albopictus is expected to invade and establish in South East England, where Culex pipiens is currently the most common native mosquito species. Biocontrol measures that use local cyclopoid copepods against Ae. albopictus may be compromised if the copepods prefer alternate Cx. pipiens prey. In this study, I assessed the predation efficiency of Megacyclops viridis copepods against Ae. albopictus larvae from France and larvae that hatched from egg rafts of Cx. pipiens collected in South East England. The experiments were conducted at 15 and 25°C, which are representative of present and future summer temperatures in South East England. Ae. albopictus larvae that survived the course of the experiment in the predator‐absent controls were significantly smaller than Cx. pipiens larvae that survived in the absence of predation. The background mortality of Cx. pipiens larvae increased with the 10‐degree increase in temperature, and the smaller size of surviving Cx. pipiens larvae at 25°C, relative to survivors at 15°C, suggests that larger Cx. pipiens larvae were more likely to die at the higher temperature setting. Across all experimental treatments, the ratio of copepod body length to mean prey length, based on larval lengths of survivors from the corresponding predator‐absent controls, was a significant predictor of the copepod's predation efficiency. Adding temperature setting to the predation efficiency model as a predictor did not improve model fit. Within the mixed prey treatments, the predation efficiency of M. viridis was 34.5 percentage points higher against Ae. albopictus prey than against Cx. pipiens prey. The higher predation efficiency that M. viridis exhibited against invasive Ae. albopictus prey, likely due to the smaller size of these larvae, supports the future use of M. viridis as a biocontrol agent in the United Kingdom.
Determinants and treatments of heart failure after transcatheter aortic valve implantation: moving up a notch
Authors: Matsushita Kensuke , Marchandot Benjamin , Trimaille Antonin , Hmadeh Sandy , Kibler Marion , Heger Joe , Carmona Adrien , Hess Sebastien , Reydel Antje , Jesel Laurence , Ohlmann Patrick , Schini‐Kerth Valerie , Morel Olivier 
Published: July 2023

AbstractTranscatheter aortic valve implantation (TAVI) has become an alternative to surgical aortic valve replacement for patients with symptomatic severe aortic stenosis in elderly and comorbid population. Significant improvement in heart function has been observed in patients undergoing TAVI, but numerous patients are readmitted to hospital for heart failure (HF). Moreover, repeat HF hospitalization is strongly associated with an adverse prognosis and increases the financial burden of health care. Although studies have identified pre‐existing and post‐procedural factors that contribute to HF hospitalization after TAVI, there is a paucity of data regarding optimal post‐procedural pharmacological treatments. This review aims to provide an overview of the current understanding of mechanisms, determinants, and potential treatments of HF following TAVI. We first review the pathophysiology of left ventricular (LV) remodelling, coronary microcirculation disorder, and endothelial dysfunction in patients with aortic stenosis and then examine the impact of TAVI on these conditions. We then present evidence of various factors and complications that may interplay with LV remodelling and contribute to HF events after TAVI. Next, we describe the triggers and predictors of early and late HF rehospitalizations following TAVI. Lastly, we discuss the potential of conventional pharmacological treatments, including renin–angiotensin blockers, beta‐blockers, and diuretics in TAVI patients. The paper explores the potential of newer drugs, including sodium–glucose co‐transporter 2 inhibitors, anti‐inflammatory drugs, and ion supplementation. Comprehensive knowledge in this field may aid in recognizing successful existing therapies, developing effective new treatments, and establishing dedicated patient care strategies during follow‐up after TAVI.
Zirconocene‐Mediated Radical Hydrophosphination
Authors: Javier‐Jiménez Diego R. , Novas Bryan T. , Waterman Rory 
Published: July 2023

AbstractHydrophosphination activity has been solicited from the parent and decamethyl zirconocene dichloride compounds, Cp2ZrCl2 and Cp*2ZrCl2. Given recent reports of photocatalytic hydrophosphination, these compounds were irradiated in the near ultraviolet (UV) as precatalysts resulting in the successful hydrophosphination of styrene substrates and activated alkenes. Irradiation appears to induce homolysis of the Cp or Cp* ligand, resulting in radical hydrophosphination. Successful detection of this radical reactivity was achieved by monitoring for EPR signals with in situ irradiation, a methodology proving to be general for the determination of radical versus closed‐shell reactivity in transition‐metal photocatalysis.
Elucidating the Mechanism and Chemoselectivity in the PBu3‐Catalyzed Rauhut‐Currier Reaction of Chalcone with Ethyl Acrylate
Authors: Ye Juan , Wang Yang 
Published: July 2023

AbstractDisclosing the chemoselectivity and regioselectivity of phosphine‐catalyzed Rauhut‐Currier (R−C) reaction remains a challenge. Here, a comprehensive study on the possible mechanisms and origins of the chemoselectivity and regioselectivity of PBu3‐catalyzed R−C reactions between ethyl acrylate and chalcone is performed by DFT. Both cross and homo R−C reactions are investigated and compared. The computational results show that the cross R−C reaction is energetically favorable than the homo R−C reaction, with head‐to‐tail product being generated preferentially. Moreover, the C−C bond formation process is identified to be the regioselectivity‐ and chemoselectivity‐determining step. The CDFT and Parr function analyses are successfully used to predict the origins of chemoselectivity and regioselectivity, respectively. This work would provide a valuable case for exploring the origins of the chemoselectivity and regioselectivity of the phosphine catalyzed reactions, which should be helpful to understand and control the selectivities by rational design.
A Highly Sterically Congested Bis‐Zinc‐Porphyrin Containing a Single Buta‐1,3‐diyne Linkage: From a Serendipitous Finding to Supramolecular Encapsulation
Authors: Kupietz Kamil , Trouvé Jonathan , Roisnel Thierry , Kahlal Samia , Gramage‐Doria Rafael 
Published: July 2023

AbstractA unique example of a bis‐zinc‐porphyrin chemical system in which both macrocycles are covalently connected with a single, short buta‐1,3‐diyne linkage placed at theorthosites of themesophenyl rings is presented. This dimeric compound resulted from an homo‐coupling side‐reaction taking place during a copper‐catalyzed click reaction between an alkyne porphyrin and 2‐azidopyridine derivatives. Its unexpected formation was rationalized by control experiments and an improved synthesis was achieved under copper‐catalyzed Glaser‐Hay coupling reaction conditions. This highly sterically congested bis‐zinc‐porphyrin derivative behaved as a supramolecular host for encapsulating ditopic molecular guests such as 1,4‐diazabicyclo[2.2.2]octane (DABCO) with association constantK1.1in the order of 106 M−1. This value is comparable to current systems that typically feature several connecting linkages between the two zinc‐porphyrin sites resulting in (supra)molecular cages ensuring a high pre‐organization. As such, the requirements to take benefit from supramolecular encapsulation can be reduced to a highly rigid, minimal covalent linkage of four atoms between zinc‐porphyrins as herein described.
The normal value and influencing factors of shear wave elastography in healthy tibial nerves: A cross‐sectional study
Authors: Shang Shiyao , Yan Wenxiao , Guo Yuping , Guo Hantao , Chen Rumin , Cong Shuzhen , Huang Chunwang 
Published: July 2023

AbstractBackground and AimsShear wave elastography is a potential method for evaluating peripheral neuropathy, but lacking reference values. The aim of this study was to measure tibial nerve stiffness in healthy individuals using shear wave elastography and to investigate the influencing factors of tibial nerve stiffness.MethodsShear wave elastography of bilateral tibial nerves was performed in 50 healthy individuals 4 cm proximal to the medial malleolus. Mean shear modulus data of tibial nerves were obtained and recorded. Intra‐ and interobserver agreement were assessed using intraclass correlation coefficients. Differences among groups (grouped by laterality, sex, age, and body mass index) were analyzed with independent‐samples t‐tests and paired t‐tests. Effect size (Cohen's d) was also calculated.ResultsThe intra‐and interobserver agreement were moderate (intraclass correlation coefficient, 0.700–0.747) for all participants, and was poor (intraclass correlation coefficient, 0.265–0.088) in very thin people (body mass index <18.5 kg/m2). The shear wave elastography measurements of the tibial nerve did not show a significant difference between legs, sexes, or different age groups. Higher values of tibial nerve stiffness were found in thinner participants.ConclusionsShear wave elastography is a method to evaluate the stiffness of peripheral nerves. The measurement results were likely influenced by body mass index of the participants.
Historical contamination with a current problem: Can mining tailings enhance coastal arsenic pollution?
Authors: do Nascimento Gisele B. , Longhini Cybelle M. , Cagnin Renata C. , Costa Eduardo S. , Silva Cesar A. , Neto Renato R. , Sá Fabian 
Published: July 2023

Abstract
The coast of Espírito Santo state (Southeast Brazil) is recognized for its environmental arsenic (As) enrichment and, over the years, mining operations have potentialized it. We aimed to evaluate the effect of Rio Doce discharge on As inputs and the role of iron ore tailings from the Fundão dam disaster in enhancing As contamination in the marine sediment. Two scenarios were evaluated: Predisaster and Postdisaster; dry and wet conditions were considered in each period. High As concentrations were found in the Predisaster (28.44 ± 13.53 µg g−1), but a significant increase in As was remarkable during the Postdisaster in the wet season, one year after the disaster (maximum of 58.39 µg g−1; geoaccumulation index (Igeo) Class 3, moderately severe pollution). On that occasion, iron (Fe) oxy-hydroxides from tailings were remobilized from the Rio Doce channel and deposited on the continental shelf bottom. Therefore, chemical interactions among Fe, As, and carbonates were enhanced, resulting in As and Fe coprecipitation and the trapping by carbonate adsorption. Rio Doce discharge seems to be the main factor in As inputs to the inner continental shelf when flooding do not occur previously in samplings, which allows further dispersion of contaminants, although this hypothesis should be tested further. Integr Environ Assess Manag 2024;20:159–168. © 2023 SETAC
Methods for estimating no-effect toxicity concentrations in ecotoxicology
Authors: Fisher Rebecca , Fox David R. , Negri Andrew P. , van Dam Joost , Flores Florita , Koppel Darren 
Published: July 2023

Abstract
A range of new statistical approaches is being developed and/or adopted in ecotoxicology that, when combined, can greatly improve the estimation of no-effect toxicity values from concentration–response (CR) experimental data. In particular, we compare the existing no-effect-concentration (NEC) threshold-based toxicity metric with an alternative no-significant-effect-concentration (NSEC) metric suitable for when CR data do not show evidence of a threshold effect. Using a model-averaging approach, these metrics can be combined to yield estimates of N(S)EC and of their uncertainty within a single analysis framework. The outcome is a framework for CR analysis that is robust to uncertainty in the model formulation, and for which resulting estimates can be confidently integrated into risk assessment frameworks, such as the species sensitivity distribution (SSD). Integr Environ Assess Manag 2024;20:279–293. © 2023 Commonwealth of Australia and The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals LLC on behalf of Society of Environmental Toxicology & Chemistry (SETAC).
Managing couples with recurrent miscarriage: A narrative review and practice recommendations
Authors: Ali Amanda , Elfituri Abdullatif , Doumouchtsis Stergios K. , Zini Mudiaga Eseajeberuo , Jan Haider , Ganapathy Ramesh , Divakar Hema , Hod Moshe , Shehata Hassan 
Published: July 2023

AbstractThere is significant variation in practice when managing couples with recurrent miscarriage (RM), with guidelines differing on the definition of RM, recommended investigations, and treatment options. In the absence of evidence‐based guidance, and following on from a paper by the authors—FIGO Good Practice Recommendations on the use of progesterone in the management of recurrent first‐trimester miscarriage—this narrative review aims to propose a global holistic approach. We present graded recommendations based on best available evidence.
Cervical sliding sign at second trimester in the prediction of early preterm birth in twin pregnancy
Authors: Tugrul Ersak Duygu , Oluklu Deniz , Beser Dilek Menekse , Hendem Derya Uyan , Tokalıoglu Eda Ozden , Kara Ozgur , Ayhan Sule Goncu , Sahin Dilek 
Published: July 2023

AbstractObjectiveTo examine the cervical sliding sign (CSS) alongside cervical length (CL) in twin pregnancies to predict preterm birth (PB).MethodsTwin pregnancies (n = 37) with no known risk factor for PB were included in this prospective study. CSS was defined as the ultrasonographic finding in which the anterior lip of the cervix slides over the posterior lip with gentle and continuous pressure application. The CSS and CL measurements were held in the second trimester. Early PB was defined as the birth of the fetus before 32 weeks of gestation. The patients were divided into two groups as CSS‐positive and CSS‐negative.ResultsWhereas 11 (29.7%) of the twin pregnancies were CSS‐positive, 26 (70.3%) were CSS‐negative. CSS positivity had a sensitivity of 75.0%, a specificity of 82.2%, a positive predictive value of 54.5%, and a negative predictive value of 92.3% to predict early PB. Multivariate logistic regression analysis revealed that CSS positivity was the only significant independent factor related to early PB.ConclusionCSS was shown to be superior to CL in providing a better insight to predict early PB. CSS evaluation should be performed in twin pregnancies.
Real world effectiveness and feasibility of pharmacist‐led preemptive CMV treatment in high risk (CMV D+R−) liver transplant
Authors: Revollo Jane Y. , Gajurel Kiran , Noell Bennett C. , Cooper Kevin T. , Hames Heather , Aldag Erika , Russo Mark W. , Casingal Vincent P. 
Published: July 2023

AbstractBackgroundRecent data have demonstrated a lower incidence of cytomegalovirus (CMV) disease utilizing preemptive CMV treatment compared to universal prophylaxis in CMV seronegative liver transplant recipients who receive allografts from CMV seropositive donors (donor‐positive [D+]recipient‐negative [R−]). However, there are little data on the feasibility and outcomes after switching transplant center protocols from universal CMV prophylaxis to preemptive treatment.MethodsAll D+R− adult liver transplant recipients underwent pharmacist‐led weekly monitoring of World Health Organization standardized quantitative plasma CMV deoxyribonucleic acid (DNA) after transplant for 6 months. Valganciclovir was started when plasma CMV viral load (VL) reached 100 IU/mL. All patients who were at least 12 months post‐liver transplant were retrospectively reviewed for incidence of CMV DNAemia and CMV disease in this cohort study.ResultsAmong 30 CMV D+R− liver transplant recipients, 23 (77%) developed target CMV DNAemia (≥100 IU/mL) at a median of 26 (range: 10–37) days after transplant with a median peak CMV VL of 947 IU/mL. Valganciclovir was started promptly with a median lag time of 1 (range: 0–5) day. There were no differences in surgical or infectious complications and readmission rates between patients with and without CMV DNAemia. Two patients had possible CMV disease in the first 6 months. None developed CMV disease in 6–12 months posttransplant. Only two patients who developed CMV DNAemia had acute cellular rejection, and none had graft loss or death. Weekly CMV polymerase chain reaction (PCR) testing was late on only three occasions for all patients before reaching the target CMV VL (<4%). Among those who remained nonviremic, 85% of scheduled weekly CMV PCR testing was completed in the first 3 months.ConclusionPreemptive CMV treatment in high‐risk liver transplant recipients is feasible and safe. There was a low rate of CMV disease in the first 12 months post‐liver transplant with a pharmacist‐led protocol.