bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Model NHT dan Minat Belajar Terhadap Hasil Belajar Mata Pelajaran EKonomi
Authors: Marnis Efi 
Published: May 2023

Penelitian ini bertujuan untuk mengungkapkan: Siswa yang diajar dengan menggunakan model tipe Numbered Heads Together memiliki hasil belajar lebih tinggi dibandingkan dengan siswa yang diajar dengan model tipe Group Investigation. Siswa yang minat belajar tinggi, Siswa yang minat belajar rendah. Interaksi antara penggunaan model pembelajaran tipe Numbered Heads Together dengan minat belajar terhadap hasil belajar pada mata pelajaran ekonomi kelas X. Jenis penelitian ini adalah eksperimen Treatment by block. Teknik analisis data dilakukan uji normalitas, uji homogenitas dan hipotesis dengan anova dua arah. Hasil penelitian menunjukkan bahwa: (1) hasil belajar siswa yang diajarkan dengan model tipe Numbered heads Together lebih tinggi secara signifikan daripada hasil belajar siswa yang diajarkan dengan model Group Investigation. (2) hasil belajar siswa yang mempunyai minat belajar tinggi dengan model tipe Numbered Heads Together lebih tinggi secara signifikan daripada hasil belajar siswa yang memiliki minat belajar tinggi dengan model tipe Group Investigation. (3) hasil belajar siswa yang mempunyai minat belajar rendah dengan model tipe Numbered Heads Together sebanding dengan hasil belajar siswa yang memiliki minat belajar rendah dengan model tipe Group Investigation. (4) tidak terdapat interaksi antara model tipe Numbered Heads Together dengan minat belajar terhadap hasil belajar.
Dynamical Mass of the Young Brown Dwarf Companion PZ Tel B
Authors: Franson Kyle , Bowler Brendan P. 
Published: May 2023

Abstract
Dynamical masses of giant planets and brown dwarfs are critical tools for empirically validating substellar evolutionary models and their underlying assumptions. We present a measurement of the dynamical mass and an updated orbit of PZ Tel B, a young brown dwarf companion orbiting a late-G member of the β Pic moving group. PZ Tel A exhibits an astrometric acceleration between Hipparcos and Gaia EDR3, which enables the direct determination of the companion’s mass. We have also acquired new Keck/NIRC2 adaptive optics imaging of the system, which increases the total baseline of relative astrometry to 15 yr. Our joint orbit fit yields a dynamical mass of

27

−
9

+
25

M

Jup

, semimajor axis of

27

−
4

+
14

au

, eccentricity of

0.52

−
0.10

+
0.08

, and inclination of

91.73

−
0.32

+
0.36

°

. The companion’s mass is consistent within 1.1σ of predictions from four grids of hot-start evolutionary models. The joint orbit fit also indicates a more modest eccentricity of PZ Tel B than previous results. PZ Tel joins a small number of young (<200 Myr) systems with benchmark substellar companions that have dynamical masses and precise ages from moving group membership.
Les blessures traumatiques des liens familiaux. Approche thérapeutique
Authors: Delage Michel 
Published: May 2023

Les blessures traumatiques des liens familiaux sont abordées différemment selon qu’une famille est victime ou selon qu’elle est elle-même traumatogène. Le travail thérapeutique s’oriente différemment : il s’agit de développer une clinique de l’offre quand la famille est victime et de pouvoir, pour le thérapeute, remplir diverses fonctions : phorique, sémaphorique et métaphorique. Lorsque la famille est traumatogène, il est le plus souvent question d’une clinique contrainte, ce qui suppose une bonne articulation-coordination des différents auteurs des champs judiciaires, éducatifs et soignants. En conclusion, les points clefs d’une résilience sont rapidement présentés.
Comment vivre comme après ? Une clinique du lien pour transformer l’effraction traumatique
Authors: Duret Isabelle 
Published: May 2023

L’article débute par l’exploration d’une série de processus psychiques individuels et systémiques avec lesquels sont aux prises les victimes d’effractions traumatiques, mais aussi ceux et celles qui en sont les témoins ou tentent de les aider. À travers l’exposé de plusieurs situations cliniques, nous allons montrer comment les effets des traumatismes dits extrêmes (abus sexuels, violence de masse, génocide…) convoquent la clinique du lien pour mobiliser les processus de résilience. La perspective du « comment vivre comme après » – expression empruntée à Guy Ausloos – sert de fil rouge pour conduire un travail thérapeutique engagé, qui favorise le (re)tissage de lien, les remaillages des liens filiatifs et affiliatifs, la réhumanisation.
CD8+ Regulatory T Cells Induced by Lipopolysaccharide Improve Mouse Endotoxin Shock
Authors: Morita Nanaka , Hoshi Masato , Tezuka Hiroyuki , Ando Tatsuya , Yoshida Sayaka , Sato Fumiaki , Yokoi Hiroyuki , Ito Hiroyasu , Saito Kuniaki 
Published: May 2023

Abstract
Sepsis is a systemic inflammatory disease caused by a bacterial infection that leads to severe mortality, especially in elderly patients, because of an excessive immune response and impaired regulatory functions. Antibiotic treatment is widely accepted as the first-line therapy for sepsis; however, its excessive use has led to the emergence of multidrug-resistant bacteria in patients with sepsis. Therefore, immunotherapy may be effective in treating sepsis. Although CD8+ regulatory T cells (Tregs) are known to have immunomodulatory effects in various inflammatory diseases, their role during sepsis remains unclear. In this study, we investigated the role of CD8+ Tregs in an LPS-induced endotoxic shock model in young (8–12 wk old) and aged (18–20 mo old) mice. The adoptive transfer of CD8+ Tregs into LPS-treated young mice improved the survival rate of LPS-induced endotoxic shock. Moreover, the number of CD8+ Tregs in LPS-treated young mice increased through the induction of IL-15 produced by CD11c+ cells. In contrast, LPS-treated aged mice showed a reduced induction of CD8+ Tregs owing to the limited production of IL-15. Furthermore, CD8+ Tregs induced by treatment with the rIL-15/IL-15Rα complex prevented LPS-induced body wight loss and tissue injury in aged mice. In this study, to our knowledge, the induction of CD8+ Tregs as novel immunotherapy or adjuvant therapy for endotoxic shock might reduce the uncontrolled immune response and ultimately improve the outcomes of endotoxic shock.
An audit of adherence to cervical cancer screening guidelines in a tertiary-level HIV clinic
Authors: Bolon Jeffrey , Samson Amy , Irwin Natalie , Murray Lyle , Mbodi Langanani , Stacey Sarah , Aikman Nicholas , Moonsamy Louell , Zamparini Jarrod 
Published: May 2023

Background: Cervical cancer is the most common malignancy affecting South African women aged 15–44 years, with a higher prevalence among women living with HIV (WLWH). Despite recommendations for a screening target of 70%, the reported rate of cervical cancer screening in South Africa is 19.3%.Objectives: To investigate the adherence of healthcare workers to cervical cancer screening guidelines in a tertiary-level HIV clinic.Method: A retrospective cross-sectional record audit of women attending the Charlotte Maxeke Johannesburg Academic Hospital HIV Clinic over a 1-month period.Results: Out of 403 WLWH who attended the clinic, 180 (44.7%) were screened for cervical cancer in the 3 years prior to the index consultation. Only 115 (51.6%) of those women with no record of prior screening were subsequently referred for screening. Women who had undergone screening in the previous 3 years were significantly older (47 years vs 44 years, P = 0.046) and had a longer time since diagnosis of their HIV (12 years vs 10 years, P = 0.001) compared to women who had not undergone screening. There was no significant difference in CD4 count or viral suppression between women who had and had not undergone screening.Conclusion: The rate of cervical cancer screening in our institution is below that recommended by the World Health Organization and the South African National Department of Health.
Public-private partnership models for rehabilitation service delivery: A scoping review
Authors: Mazibuko Senzelwe M. , Nadasan Thayananthee , Govender Pragashnie 
Published: May 2023

Background: Public-private partnership (PPP) for the delivery of health services is known to improve access to healthcare, yet little is known about its utilisation for rehabilitation services, particularly in sub-Saharan Africa (SSA).Objectives: As a first step to generating evidence to develop a PPP model for physiotherapy service delivery in South Africa, our study mapped and described available research evidence on PPP models for rehabilitation services in the global literature.Method: The Arksey and O’Malley framework guided our scoping review. Published research on rehabilitation and PPP was searched in five databases from 2000 to August 2022 using keywords, Medical Subject Headings (MeSH) and Boolean terms. Two reviewers independently completed the titles, abstracts and full-text screening of the articles and data extraction from the included articles. A narrative synthesis was conducted, and summaries of the findings are reported.Results: Nine articles were included from a total of 137 obtained from the evidence searches. Of these, five were from Australia and the others from Hong Kong, Denmark, Bangladesh and the Netherlands. All the included articles showed evidence of PPP models for physiotherapy service delivery.Conclusion: Our study suggests that PPP models for physiotherapy service delivery exist, particularly in high-income countries (HICs). It also highlights limited research in low- and middle-income countries (LMICs).Clinical implications: There is a need for primary studies to generate further evidence and develop innovative PPP models for rehabilitation services for the populations who need them most as part of efforts towards improving access to healthcare in LMICs.
Nonalcoholic Fatty Liver Disease in Polycystic Ovary Syndrome
Authors: Hima Hafeja Akhter , Hannan Miah Md Abdul , Ghosh Nipa Rani , Sultana Sazia , Akter Tanjina , Aalpona Fatema Tuz Zahura , Kamrul-Hasan A. B. M. 
Published: May 2023

Background and Objectives:
Nonalcoholic fatty liver disease (NAFLD) and polycystic ovary syndrome (PCOS) are two prevalent metabolic disorders characterized by insulin resistance. A bidirectional relationship exists between NAFLD and PCOS. NAFLD prevalence is significantly higher and more severe in women with PCOS. This study was conducted to generate data regarding the frequency of NAFLD among Bangladeshi women with PCOS.

Materials and Methods:
This cross-sectional study was conducted at the endocrinology and gynecology outpatient department of a tertiary hospital in Bangladesh from October 2020 to December 2021. All adult women diagnosed with PCOS by the revised Rotterdam criteria underwent ultrasonographic evaluation for hepatic steatosis. Relevant sociodemographic and clinical data were obtained from all; all underwent hormonal and metabolic assessment.

Results:
Among 120 women (age 33.67 ± 10.15 years) with PCOS studied, 32 (26.7%) had NAFLD. NAFLD frequency was higher in rural than urban areas. Clinical hyperandrogenism (HA) was less frequent in the NAFLD group than in the non-NAFLD group. Two groups did not vary in the frequencies of overweight, obesity, abdominal obesity, and hypertension. Hormonal parameters were indifferent in the two groups; both groups had a similar frequency of biochemical HA. Both groups had similar plasma glucose levels and glycemic status. NAFLD patients had lower high-density lipoprotein cholesterol and higher triglyceride than the non-NAFLD patients; total and low-density lipoprotein cholesterol were similar in the two groups. Although metabolic syndrome frequency was higher (43.8% vs. 33.0%) in the NAFLD group, the difference was insignificant (P = 0.290). Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were more elevated in the NAFLD group; AST: ALT ratios were identical in the two groups. In binary logistic regression analysis, only clinical HA was associated with a lower risk of NAFLD among the study participants.

Conclusion:
More than one-fourth of women with PCOS have NAFLD in this study. A large-scale, multicenter study may better explain NAFLD's association and risk factors in women with PCOS.
Effect of zinc oxide nanoparticles on cellular stress in Ehrlich ascites carcinoma
Authors: Morsy Sara , Abd-Ellatif Rania N , Soliman Nema A , Ibrahim Wafaa M 
Published: May 2023

Background
Cancer cells are characterized by high cellular stress that is considered crucial for cancer cell survival and metastasis.

Aim
In this study, we assessed cellular stress in Ehrlich ascites carcinoma (EAC) cells before and after treatment with intraperitoneal zinc oxide nanoparticles.

Materials and methods
This experiment was performed on six groups of mice: 90 female albino mice were included in this study and were divided into six groups (n=15 per group): C [saline treated mice (20 ml/Kg intraperitoneal (i.p.)], CZn20/2d [ZnO NP-treated mice (20 mg/kg i.p. every other day], EC [untreated EAC-bearing mice], EZn 10/d [EAC-bearing mice administered with ZnO NPs 10 mg/kg everyday], EZn 10/2d [EAC-bearing mice administered with ZnO NPs 10 mg/kg every other day], EZn20/2d [EACs-bearing mice administered with ZnO NPs 20 mg/kg every other day]. After 2 weeks, the ascitic fluid and mammary gland were collected to measure the level of nitric oxide (NO) and peroxynitrite.

Results
Based on this results, there was a significantly high level of NO and peroxynitrite in the EAC groups compared with the control group. Zinc oxide nanoparticles significantly decreased the level of NO and peroxynitrite in the EAC groups compared with the control group.

Conclusion
This study implied that cancer cells have higher cellular stress, and it was efficiently decreased by treatment with zinc oxide nanoparticles indicating its efficacy against cancer cells.
The role of CXCR5+ CD4+T-follicular helper cells in idiopathic thrombocytopenic purpura
Authors: El-Sayed Nada E.-S.T. , Fouda Mohammed H.M. , El-Shanshory Mohamed R. , Ghaith Fatma M. 
Published: May 2023

Background
Primary immune thrombocytopenic purpura (ITP) is an autoimmune illness characterized by increased platelet breakdown in the peripheral blood as well as impaired platelet production and it is also characterized by platelet counts less than 100 × 109/L. T-follicular helper (TFH) cells have been linked to the pathogenesis of autoimmune conditions.

Aim
The study’s aim was to study the role of TFH cells and their function in ITP children.

Patients and methods
This research involved 25 ITP patients and 20 age-matched and sex-matched controls, with the frequency of circulating TFH cells measured by BD FACS Calibur Flowcytometer in both ITP patients and healthy controls.

Results
The results showed that the ratio of circulating CD4+ CXCR5+ PD1+ (TFH) in ITP (+) patients, that is, (ITP patients with antiplatelet antibody-positive results) was dramatically higher than those of ITP (−) patients, that is, (ITP patients with antiplatelet antibody-negative results) and it was discovered that the ratios of circulating CD4+ CXCR5+ PD1+ (TFH) were dramatically higher in ITP (+) patients than the control group. However, the ratio of circulating CD4+ CXCR5 +PD1+ (TFH) was not dramatically different between ITP (−) patients and the control group.

Conclusion
Patients with ITP have an increased number of TFH cells, which prove its critical role in B-cell proliferation, resulting in the development of autoantibodies that contribute to the pathophysiology of ITP.
A Comparative Study of the Efficacy of Thulium Fiber Laser Enucleation and Transurethral Resection for Medium- to Large-Size Prostate
Authors: Mahajan Abhay Dinkar , Mahajan Sumeeta Abhay 
Published: May 2023

Abstract

Purpose:
The objective of this study was to evaluate the efficacy and safety of the newer, thulium fiber laser enucleation of the prostate (ThuFLEP) versus the transurethral resection of the prostate (TURP) for medium- to large-volume benign prostatic hyperplasia (BPH).

Materials and Methods:
We performed a single-center retrospective study between May 2020 and June 2021. Among these, we included patients >50 years of age, with prostate size >80 cc, International Prostate Symptom Score (IPSS) >19, and maximum urine flow rate (Qmax) <15 mL/s. All patients underwent either TURP or ThuFLEP. Preoperative parameters such as IPSS score, quality of life (QoL) score, Qmax, and residual urine were assessed.

Results:
Of the total of 101 patients, 29 underwent ThuFLEP and 72 TURP. The mean prostate volume was significantly higher in the ThuFLEP group compared to the TURP (P = 0.01). The mean operative time was longer for ThuFLEP compared to TURP (P < 0.0001). No significant difference was noted in the postoperative hematuria (P = 0.29) and mean postoperative hemoglobin (P = 0.37). The QoL scores were significantly improved with ThuFLEP than TURP (P = 0.0006). Compared to a day after catheter removal, the proportion of patients with stress, urge, and total incontinence was significantly reduced at the end of 1 month in the ThuFLEP group (P < 0.00001); however, it was significantly greater than with TURP (P < 0.05). At 3 months, no significant difference was found between IPSS (P = 0.37) and Qmax (P = 0.98) scores between the groups; however, the decrease from baseline was significant for IPSS (P < 0.0001). The Clavien–Dindo Grade I and II complications were 31% and 13.8%, respectively, for ThuFLEP and 8.3% and 1.4% for TURP. There was no significant difference of patients with late complications.

Conclusion:
ThuFLEP demonstrated efficacy similar to TURP in medium- to larger-size BPH in terms of IPSS and Qmax but had significant improvement in QoL scores. The overall complications with ThuFLEP were higher as compared to TURP.
AN ANALYSIS OF SOCIAL VALUES IN EKA KURNIAWAN’S CANTIK ITU LUKA
Authors: Zalukhu Zeni Merlinda , Tambunan Dermawati L. , Silaban Gongsar 
Published: May 2023

Penelitian ini berjudul Analisis Nilai Sosial dalam novel Cantik Itu Luka karya Eka Kurniawan. Analisis ini di fokuskan pada nilai sosial dan penggambaran nilai sosial dalam novel Cantik Itu Luka karya Eka Kurniawan. Penelitian ini merupakan penelitian deskriptif kualitatif. Data penelitian berupa kutipan kalimat, dialog atau pun paragraf dalam novel Cantik Itu Luka. Data dalam penelitian ini diaplikasikan oleh teori Burhan mengatakan nilai sosial terbagi tiga jenis yaitu pertama nilai hubungan manusia dengan diri sendiri, kedua nilai hubungan manusia dengan masyarakat, dan ketiga nilai hubungan menusia dengan Tuhan. Ketiga jenis nilai merangkumi setiap kelakuan seseorang manusia dalam sehari-hari. Hasil penelitian menunjukkan bahwa nilai sosial yang terkandung dalam novel ini meliputi kasih sayang, peduli, tolong menolong dan tanggung jawab. Penggambaran nilai sosial dalam novel ini adalah melakukan yang terbaik untuk orang yang anda cintai sebagai penggambaran kasih sayang dan tanggung jawab, rasa empati setiap anggota manusia untuk membantu orang lain sebagai penggambaran kepedulian, membantu meringankan kesulitan yang dirasakan orang lain sebagai penggambaran tolong menolong.
Mosteirinho de São Francisco in Paudalho, Brazil: Building Typology Adaptation in Colonial Architecture
Authors: Rolim Renan Cornélio Vieira de Souza , Gilabert-Sansalvador Laura , Viñals María José 
Published: May 2023

The Mosteirinho de São Francisco, in the city of Paudalho (Brazil), is a unique example of Franciscan religious architecture that reflects a very specific historical context of the area. It was built during the period of Dutch domination of Northeastern Brazil (1630-1654), characterized by territorial disputes and religious persecution between Dutch (Protestants) and Portuguese (Catholics). Designed in this emergency context, the building was conceived with a simple and compact layout, adapting the typology and spaces of a Franciscan convent to the site and specific circumstances. An example of this is the addition of two connected aisles to the nave, providing an architectural promenade around this main space: a modest but ingenious adaptation of the cloister concept. Nowadays the building is completely abandoned, in an advanced state of decay and in a judicial process regarding its property. Even its heritage protection is at risk. This paper presents the results of an architectural research about this building with the aim of claiming the importance of its preservation.
Translated anthologies: (Re)establishing adaptive reuse as a transdisciplinary cultural practice
Authors: Mac Aoidh Colm , Van Cleempoel Koenraad 
Published: May 2023

The immediacy of the climate crisis has necessitated a paradigm shift away from endless cycles of demolition and reconstruction towards more ecologically and socially sustainable architectural practices that focus on the adaptive reuse of existing buildings. Many recent approaches have tended however to concentrate on the technical, material and economic aspects of reuse at the expense of the equally important social and cultural aspects.This paper discusses a recently-launched project at Hasselt University in Belgium that attempts to address this myopic imbalance through the development of a conceptual framework that firmly repositions adaptive reuse as a transdisciplinary practice, engaged not only with ‘hard’ values like technical and material concerns, but also ‘soft’ values encompassing the integral cultural and social aspects that give places meaning.The project sets out to curate an anthology of textual and non-textual sources from both within and beyond the discipline of architecture that can contribute to the emerging theory of adaptive reuse and situate it within wider contemporary discourses. This collected body of knowledge is then examined through the critical lens of translation, investigating the acts of translation involved in reconciling different traces, time periods, interventions and actors, as a way to synthesise the various meanings uncovered and suggest how the intimate and reciprocal relay between theory, practice and education might be strengthened.Through an exploration of anthologising as a critical practice and translation as a critical lens, the paper highlights how proposing a theoretical foundation for adaptive reuse can help reinforce its cross-cutting nature as a cultural activity, at the same time emphasising the critical role it has to play in any future sustainable development.