bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multiyear changes in oceanographic factors of the autumn migration of the Black Sea anchovy to the shores of Crimea from satellite data in 2000–2021
Authors: Panov B. N. , Smirnov S. S. , Spiridonova E. O. 
Published: August 2023

The purpose of this work is to analyze long-term changes in oceanographic indicators in the southeastern area of the northwestern Black Sea in November-December 2000–2021, which determine the migration activity and fishery performance of the Black Sea hammerhead off the coast of Crimea. Materials and methods used: The fishery statistics, data of information system Copernicus Marine Service of satellite altimetry and surface temperature of waters near the western coast of the Crimean Peninsula in November-December 2000–2021, graphic and statistical methods of the analysis of these data were used in work. Novelty: The element of novelty in the work is the use of oceanographic satellite data in the study of the behaviour of the Black Sea anchovy and long-term changes in its catch off the coast of Crimea. Result: During the period under consideration, the tendency of catch increase of the Black Sea anchovy of the Crimean coast is obvious. The main reasons for the activation of the autumn migration of the Black Sea anchovy to the shores of Crimea is a multi-year increase in sea surface temperature and the strengthening of south-eastern currents to the west of the Crimean Peninsula. Practical significance: The revealed causes of the mass autumn approaches of the Black Sea anchovy to the Crimean coast allow hoping for possibilities of their use in forecasting the results of the Black Sea anchovy fishing in the Crimean fishing area, and also give grounds for continuing research with special attention to monitoring of the Black Sea anchovy occurrence on the Crimean shelf.
Biological indicators and traceability of the origin of Russian sturgeon juveniles in the lower reaches of the Volga River and the north- western part of the Caspian Sea
Authors: Shipulin S. V. , Vlasenko S. A. , Kirillov D. E. , Kozlova N. V. , Lepilina I. N. , Makarova E. G. , Mikhailova A. V. , Tikhonova Je. Ju. , Chaplygin V. A. , Shcherbakova V. D. , Barmintseva A. A. , Burlachenko I. V. , Mugue N. S. 
Published: August 2023

The aim of the work: characterization of juveniles released from sturgeon hatcheries into the natural habitat with individual identification of individuals. Methods: Ichthyological researches in the Volga River and its watercourses were surveyed using a 4.5 m fry trawl; in the western part of the Northern Caspian, a trawl survey was carried out using a 9 m trawl and the developed grid of stations, adjusted to take into account the sea level decrease. The trophological material was processed by the quantitative-weight method, followed by the calculation of private and general indices of the filling of the digestive tracts. Molecular genetic methods for the analysis of microsatellite loci and sequencing of a fragment of the control region of mitochondrial DNA were used. Novelty: the origin of the Russian sturgeon and the contribution of artificial reproduction from Russian sturgeon hatcheries to the Volga- Caspian fishery basin were determined by molecular genetic methods. Results: The composition of food organisms and the degree of fattening of Russian sturgeon juveniles after their migration to the sea were determined. The contribution of artificial reproduction from Russian sturgeon hatcheries to the replenishment of the Russian sturgeon population of the Volga- Caspian basin in the period 2016–2021 for fingerlings was averaged 80 %. Practical significance: The intensity of downstream migration in the Volga River and its watercourses of juveniles released from sturgeon hatcheries was studied. The presented data was made it possible to determine the main localization sites of Russian sturgeon juveniles depending on the species composition and abundance of food organisms in the northwestern part of the Caspian Sea. Based on the results of genotyping of spawners at sturgeon hatcheries and juveniles caught in the Northern Caspian, an assessment was made of the effectiveness of the work of the sturgeon hatcheries in 2016–2021.
Design and Validation of a Torso-Dynamics Estimation System (TES) for Hands-Free Physical Human-Robot Interaction*
Authors: Song Seung Yun , Guo Yixiang , Yuan Chentai , Marin Nadja , Xiao Chenzhang , Bleakney Adam , Elliott Jeannette , Ramos Joao , Hsiao-Wecksler Elizabeth 
Published: August 2023

<p>This is a submitted draft of a paper on the design and validation of a Torso-dynamics Estimation System (TES). The TES consisted of a Force Sensing Seat (FSS) and an inertial measurement unit (IMU) that measured the kinetics and kinematics of the subject's torso motions. The FSS estimated the 3D forces, 3D moments, and 2D COPs while the IMU estimated the 3D torso angles. To validate the TES, the FSS and IMU estimates were compared to gold standard research equipment (AMTI force plate and Qualisys motion capture system, respectively).</p>
<p>Potential applications of the TES include physical human-robot interaction (pHRI) for navigating riding or remote robots.</p>
<p>The data and data processing code from this study are open source and can be found via the following links:</p>
<ul>
<li>IEEE DataPort with data: https://ieee-dataport.org/documents/validation-study-torso-dynamics-estimation-system-tes-hands-free-physical-human-robot </li>
<li>GitHub repository with code: https://github.com/ssong47/TorsodynamicsEstimationSystem </li>
</ul>
<p><br></p>
Uma História de Sinergias: as Relações entre UFRJ-IBGE
Authors: De Almeida Roberto Schmidt 
Published: August 2023

O artigo traz um histórico das principais relações acadêmicas entre o conjunto de instituições universitárias que deram origem à atual Universidade Federal do Rio de Janeiro (UFRJ), à Universidade do Distrito Federal (UDF), à Universidade do Brasil (UB), e ao Instituto Brasileiro de Geografia e Estatística (IBGE), apresentando seus principais líderes acadêmicos, juntamente com seus papéis, nos diferentes períodos históricos.
Mapeamento participativo e cartografia social: aspectos conceituais e trajetórias de pesquisa, organizado por Raquel Dezidério Souto Paulo, Márcio Leal de Menezes e Manoel do Couto Fernandes. Rio de Janeiro: Instituto Virtual para o Desenvolvimento Sustentável – IVIDES.org. 214p., 2021
Authors: De Carvalho Carolina Monteiro 
Published: August 2023

O Mapeamento Participativo é um método que vem sido amplamente explorado por pesquisas ambientais, sociais e urbanas, atualmente. O livro Mapeamento participativo e cartografia social: aspectos conceituais e trajetórias de pesquisa apresenta, de forma aprofundada, os conceitos fundamentais deste método, como a sua origem, motivação e contribuições para o impacto social e ambiental, tais como i) aumento da capacidade em gerar, manejar e comunicar informações espaciais; ii) estímulo à inovação e iii) encorajamento das mudanças sociais positivas.
Conservation agriculture practices in a peanut cropping system: Effects on pod yield and soil penetration resistance
Authors: Betiol Olavo , Bolonhezi Denizart , Leal Élcio Ríos Perez , Gruener Chandler Edwin , Michelotto Marcos Doniseti , Furlani Carlos Eduardo Angeli , Ruiz Fábio Fiori 
Published: August 2023

ABSTRACT

Conservation agriculture principles applied to peanut can reduce soil erosion and production costs when cultivated in rotation with sugarcane. Still, the problem with soil compaction is the leading cause of skepticism about the efficacy of this practice. This research aimed to study the effect of three soil management strategies compared with conventional for peanut cv. IAC-OL3, cultivated in rotation with sugarcane using the MEIOSI (method of intercropping occurring simultaneously) system for agronomic practices with additional analysis on changes in soil physics properties. The trial was conducted in 2019-2020 in Planalto municipality (São Paulo, Brazil) under a green-harvested sugarcane field, using a randomized complete block experimental design. The trial consisted of four soil management treatments (conventional tillage, minimum tillage with chisel, strip-tillage, and no-tillage) with five replications. Although no differences were verified in soil bulk density and porosity among treatments, the highest values of soil penetration resistance were observed in no-tillage treatment for all evaluations (before planting, at the beginning of flowering, and before and after harvesting) in comparison with conventional tillage. The difference in soil penetration resistance among the treatments diminished from planting to the end of the cycle. Furthermore, low soil disturbance and maximum covering with straw significantly increased the available water capacity and reduced the incidence and severity of groundnut ringspot virus (GRSV) on peanut plants. Consequently, both minimum-tillage and no-tillage have increased the pod yield on average by 695 and 991 kg ha
-1
more than strip-tillage and conventional tillage, respectively, without differences in terms of quality and pod losses.
Male Breast Cancer in Dr. Hasan Sadikin General Hospital: A Serial Case
Authors: Sari Rantapina Kurnia , Maman Abdurrahman  , Monty Priosodewo Soemitro  , Kiki Akhmad Rizki  , Raden Yohana  
Published: August 2023

Background: Male breast cancer is a rare case. It accounts for 1% of all breast cancer cases. Both female and male breast cancers were influenced by the same risk factors. Male breast cancer patients are typically associated with advanced stages, higher grades, higher prevalence of hormone receptor-positive, and a worse prognosis. Many factors can explain the late diagnosis in men: absence of screening programs, lack of awareness about the condition by the male population, embarrassment due to a stigmatization of the disease, and misjudgment by primary care physicians. The aim of study is to improve the knowledge about the biology tumor and characteristics, risk factor, and management of male breast cancer.
Case presentation: Two patients who were studied were a man with 50 years old, without malignancy on their family and testicles disease. First patients was diagnosed with mucinous adenocarsinoma grade II on right breast luminal A subtype T4bN0M0 and second patient was diagnosed with Ductal carcinoma in situ on right breast luminal B Her2 negative subtype TisN0M0 as preoperative diagnosis and Invasive solid papillary carcinoma grade III on right breast T2N0M0 as post operative diagnosis. Both of them were operated with modified radical mastectomy. First patient was given neoadjuvant chemotherapy, adjuvant chemotherapy and tamoxifen as endocrine therapy. Second patient was given adjuvant chemotherapy and tamoxifen as endocrine therapy.
Conclusion: Both of patients on serial cases are male breast cancer with hormone receptor positive and they were given endocrine therapy. The majority characteristic of male breast cancer was hormone receptor-positive. Management of male breast cancer is similar overall to management of female breast cancer in modality surgery, chemotherapy, endocrine therapy, and radiotherapy.
Upaya Meningkatkan Hasil Belajar Melalui Model Open Ended Learning Berbantu Media Kartu Puzzle Huruf Kelas I Semester 2 SD Negeri 1 Wonokromo
Authors: Puspaningsih Wahyu 
Published: August 2023

Penelitian ini bertujuan untuk meningkatkan Hasil Belajar Melalui Model Open Ended Learning Berbantu Media Kartu Puzzle Huruf Kelas I Semester 2 SD Negeri 1 Wonokromo. Jenis penelitian ini merupakan penelitian tindakan kelas yang didisain dengan menggunakan model Kemmis & Mc Taggart. Subjek dalam penelitian ini adalah siswa kelas I SD Negeri 1 Wonokromo dengan jumlah 7 siswa dan dilaksanakan dalam 2 siklus. Instrumen pengumpulan data yang digunakan adalah tes untuk mengetahui dan mengukur hasil belajar siswa. Data yang didapatkan pada prasiklus adalah 3 siswa atau 43% lulus nilai KKM dengan rata-rata 67 yang sudah mendapatkan nilai mencapai kriteria. Pada siklus I mengalami peningkatan sebesar 57% atau 4 siswa tuntas KKM dengan rata-rata 75 dan pada siklus ke II semua siswa lulus KKM atau 100% siswa mencapai KKM dengan rata-rata 90. Dari hasil diatas, dapat disimpulkan jika pembelajaran Open Ended Learning mampu meningkatkan hasil belajar siswa sehingga dapat dikatakan penelitian ini telah berhasil.
Pengaruh Kompetensi SDM, Moralitas Individu, Dan Sistem Pengendalian Internal Terhadap Pencegahan Fraud
Authors: Komalasari Tika 
Published: August 2023

The purpose of this research is to examine and explain the influence of SDM competence, morality individual and internal control systems on fraud prevention. his research is a quantitative study with a descriptive research design. The data source in this study uses primary data obtained from the results of the distribution of questionnaires to all officials in the village recorded in Bantargebang District of 45 respondents. This research was conducted in Bantargebang Village, Cikiwul Village, Ciketing udik village and sumur batu village. The results of this study indicate that SDM competence, morality individual, and internal control systems, have a significant simultaneous effect on fraud prevention. partially, the SDM competence has no effect on fraud prevention, morality individual has an effect on fraud prevention and internal control system has no effect on fraud prevention.

Keywords: SDM Competence, Morality individual, internal control system, fraud prevention
A Synthetic Poly(A) Tail Targeting Extracellular CIRP Inhibits Sepsis
Authors: Murao Atsushi , Jha Alok , Ma Gaifeng , Chaung Wayne , Aziz Monowar , Wang Ping 
Published: August 2023

Abstract
Sepsis is an infectious inflammatory disease that often results in acute lung injury (ALI). Cold-inducible RNA-binding protein (CIRP) is an intracellular RNA chaperon that binds to mRNA’s poly(A) tail. However, CIRP can be released in sepsis, and extracellular CIRP (eCIRP) is a damage-associated molecular pattern, exaggerating inflammation, ALI, and mortality. In this study, we developed an engineered poly(A) mRNA mimic, AAAAAAAAAAAA, named A12, with 2′-O-methyl ribose modification and terminal phosphorothioate linkages to protect it from RNase degradation, exhibiting an increased half-life. A12 selectively and strongly interacted with the RNA-binding motif of eCIRP, thereby preventing eCIRP’s binding to its receptor, TLR4. In vitro treatment with A12 significantly decreased eCIRP-induced macrophage MAPK and NF-κB activation and inflammatory transcription factor upregulation. A12 also attenuated proinflammatory cytokine production induced by eCIRP in vitro and in vivo in macrophages and mice, respectively. We revealed that treating cecal ligation and puncture–induced sepsis with A12 significantly reduced serum organ injury markers and cytokine levels and ALI, and it decreased bacterial loads in the blood and peritoneal fluid, ultimately improving their survival. Thus, A12’s ability to attenuate the clinical models of sepsis sheds lights on inflammatory disease pathophysiology and prevention of the disease progress.
Probiotic Lactobacillus and the potential risk of spreading antibiotic resistance: a systematic review
Authors: Shahali Ali , Soltani Rasool , Akbari Vajihe 
Published: August 2023

Background and purpose:

Lactobacillus, the most popular probiotic, has recently gained more attention because it is a potential reservoir of antibiotic resistance. This review summarized and discussed the phenotypic-genotypic characteristics of antibiotic resistance.

Experimental approach:
Google Scholar, PubMed, Web of Science, and Scopus were searched up to February 2022. The inclusion criteria were all studies testing antibiotic resistance of probiotic Lactobacillus strains present in human food supplementation and all human/animal model studies in which transferring antibiotic-resistant genes from Lactobacillus strains to another bacterium were investigated.

Findings/Results:
Phenotypic and genotypic characterization of Lactobacillus probiotics showed that the most antibiotic resistance was against protein synthesis inhibitors (fourteen studies, 87.5%) and cell wall synthesis inhibitors (ten studies, 62.5%). Nine of these studies reported the transfer of antibiotic resistance from Lactobacillus probiotic as donor species to pathogenic bacteria and mostly used in vitro methods for resistance gene transfer.

Conclusion and implications:
The transferability of resistance genes such as tet and erm in Lactobacillus increases the risk of spreading antibiotic resistance. Further studies need to be conducted to evaluate the potential spread of antibiotic resistance traits via probiotics, especially in elderly people and newborns.
Bioinformatic analysis of highly consumed phytochemicals as P-gp binders to overcome drug-resistance
Authors: Rajaei Narges , Rahgouy Ghazaleh , Panahi Nasrin , Razzaghi-Asl Nima 
Published: August 2023

Background and purpose:
P-glycoprotein (P-gp) is an adenosine triphosphate (ATP)-dependent membrane efflux pump for protecting cells against xenobiotic compounds. Unfortunately, overexpressed P-gp in neoplastic cells prevents cell entry of numerous chemotherapeutic agents leading to multidrug resistance (MDR). MDR cells may be re-sensitized to chemotherapeutic drugs via P-gp inhibition/modulation. Side effects of synthetic P-gp inhibitors encouraged the development of natural products.

Experimental approach:
Molecular docking and density functional theory (DFT) calculations were used as fast and accurate computational methods to explore a structure binding relationship of some dietary phytochemicals inside distinctive P-gp binding sites (modulatory/inhibitory). For this purpose, top-scored docked conformations were subjected to per-residue energy decomposition analysis in the B3LYP level of theory with a 6-31g (d, p) basis set by Gaussian98 package.

Findings/Results:
Consecutive application of computational techniques revealed binding modes/affinities of nutritive phytochemicals within dominant binding sites of P-gp. Blind docking scores for best-ranked compounds were superior to verapamil and rhodamine-123. Pairwise amino acid decomposition of superior docked conformations revealed Tyr303 as an important P-gp binding residue. DFT-based induced polarization analysis revealed major electrostatic fluctuations at the atomistic level and confirmed larger effects for amino acids with energy-favored binding interactions. Conformational analysis exhibited that auraptene and 7,4′,7″,4‴-tetra-O-methylamentoflavone might not necessarily interact to P-gp binding sites through minimum energy conformations.

Conclusion and implications:
Although there are still many hurdles to overcome, obtained results may propose a few nutritive phytochemicals as potential P-gp binding agents. Moreover; top-scored derivatives may have the chance to exhibit tumor chemo-sensitizing effects.
Honokiol inhibits the growth of hormone-resistant breast cancer cells: its promising effect in combination with metformin
Authors: Mikhaevich Ekaterina I. , Sorokin Danila V. , Scherbakov Alexander M. 
Published: August 2023

Background and purpose:
Primary and metastatic breast cancers still represent an unmet clinical need for improved chemotherapy and hormone therapy. Considerable attention has been paid to natural anticancer compounds, especially lignans. The study aimed to evaluate the activity of several lignans against breast cancer cells and assess the effect of leading lignans on signaling pathways in combination with metformin.

Experimental approach:
Human breast cancer cell lines MCF7 (hormone-dependent), MDA-MB-231, and SKBR3 (hormone-independent) were used. A hormone-resistant MCF7/hydroxytamoxifen (HT) subline was obtained by long-term cultivation of the MCF7 line with hydroxytamoxifen. Antiproliferative activity was assessed by the MTT test; the expression of signaling pathway proteins was evaluated by immunoblotting analysis.

Findings/Results:
We evaluated the antiproliferative activity of lignans in breast cancer cells with different levels of hormone dependence and determined the relevant IC50 values. Honokiol was chosen as the leading compound, and its IC50 ranged from 12 to 20 μM, whereas for other tested lignans, the IC50 exceeded 50 μM. The accumulation of cleaved PARP and a decrease in the expression of Bcl-2 and ERα in MCF7/HT were induced following the combination of honokiol with metformin.

Conclusions and implications:
Honokiol demonstrated significant antiproliferative activity against both hormone-dependent breast cancer cells and lines with primary and acquired hormone resistance. The combination of honokiol with metformin is considered an effective approach to induce death in hormone-resistant cells. Honokiol is of interest as a natural compound with antiproliferative activity against breast cancers, including resistant tumors.
Managing patients with vitiligo by narrowband–ultraviolet-B and systemic vitamin D
Authors: Alsabbagh Manal M. , Kassim Azad K. 
Published: August 2023

Background
The role of vitamin D in autoimmune disorders in general and in vitiligo in specific has drawn the attention of many authors recently. Topical vitamin D is known to help in restoring pigmentation in vitiligo. The effect of vitamin D deficiency in vitiligo is still not fully understood.

Aim
To examine the effect of correcting vitamin D deficiency on the clinical improvement of vitiligo.

Setting and design
A randomized clinical trial where patients attending the Dermatology Clinic and diagnosed with vitiligo were invited to participate.

Patients and methods
In all, 26 patients with vitiligo and vitamin D deficiency were recruited, and by simple randomization, they were assigned into one of the 12-week therapeutic groups: a combined therapy of narrowband–ultraviolet-B (NB–UVB) and oral vitamin D, and a monotherapy of oral vitamin D or a monotherapy of NB–UVB. Serum level of vitamin D was measured at three occasions; before and after treatment, and at onset of repigmentation. Statistical analysis: SPSS was used for statistical analysis; A P value of less than 0.05 was considered as statistically significant.

Results
Patients on a combined therapy of NB–UVB and oral vitamin D required the shortest time for repigmentation (2.4 weeks) compared with monotherapy of vitamin D (4.8 weeks) or phototherapy (6.4 weeks) (P<0.05). However, the relationship between serum vitamin D level and onset of repigmentation was insignificant.

Conclusions
Replacement of vitamin D might positively influence the course of vitiligo management when combined with phototherapy. Further studies are required to confirm and identify the exact role vitamin D.