bluuebunny/crossref_metadata_2025_split huggingface dataset:
Vertrauen durch digitale Identifizierung: Über den Beitrag von SSI zur Integration von dezentralen Oracles in Informationssysteme
Authors: Babel Matthias , Gramlich Vincent , Guthmann Claus , Schober Marcus , Körner Marc-Fabian , Strüker Jens 
Published: March 2023

ZusammenfassungDie Vernetzung kommunikationsfähiger Geräte schreitet aktuell schnell voran und verspricht durch eine Ende-zu-Ende-Digitalisierung von Prozessen Effizienzgewinne und neue Anwendungsmöglichkeiten. Die Verifizierung von Endgeräten ist insbesondere bei kritischen Infrastrukturen wie der Energieversorgung eine notwendige Bedingung. Unter anderem für die aktive Integration von Kleinstanlagen wie Photovoltaikanlagen oder Wärmepumpen in das Stromnetz stellt sich die Frage, wie Stamm- und Bewegungsdaten von Verbrauchs- und Erzeugungsanlagen vertraulich und unverändert verfügbar gemacht werden können. Mit der Beantwortung dieser Fragestellung hat sich das Projekt „Digitale Maschinen-Identitäten als Grundbaustein für ein automatisiertes Energiesystem (BMIL)“ im Rahmen des Future Energy Lab der Deutschen Energie-Agentur (dena) beschäftigt. Für die vertrauensvolle Einspeisung und Integration von dezentral erzeugten Daten folgt das Projekt dem Paradigma der selbstbestimmten Identitäten (engl.: SSI). Hierbei werden intelligente Messsysteme bzw. Smart Meter Gateways (SMGWs) mit Maschinenidentitäten ausgestattet. Dies ermöglicht Vertrauensketten zu nutzen, um Bewegungsdaten verbunden mit verifizierbaren Stammdaten in digitale Strommärkte zu integrieren. Im Rahmen dieses Artikels werden die Ergebnisse des BMIL-Projekts innerhalb einer Fallstudie aufgearbeitet und konkrete Handlungsempfehlungen für die Praxis zur Lösung des Oracle-Problems mit Hilfe von SSI abgeleitet.
Risk factors of catheter- associated bloodstream infection: Systematic review and meta-analysis
Authors: Lafuente Cabrero Elisabeth , Terradas Robledo Roser , Civit Cuñado Anna , García Sardelli Diana , Hidalgo López Carlota , Giro Formatger Dolors , Lacueva Perez Laia , Esquinas López Cristina , Tortosa Moreno Avelina 
Published: March 2023

Introduction
The prevalence of catheter-associated bloodstream infections (CLABSI) is high and is a severe health problem associated with an increase in mortality and elevated economic costs. There are discrepancies related to the risk factors of CLABSI since the results published are very heterogeneous and there is no synthesis in the description of all the predisposing factors.

Objective
We aimed to perform a systematic review and meta-analysis to synthesize and establish the risk factors predisposing to CLABSI reported in the literature.

Method
This is a systematic review of observational studies following the PRISMA recommendations. MEDLINE and CINAHL databases were searched for primary studies from 2007 to 2021. The protocol was registered in PROSPERO CRD42018083564.

Results
A total of 654 studies were identified, 23 of which were included in this systematic review. The meta-analysis included 17 studies and 9 risk factors were analyzed (total parenteral nutrition (TPN), chemotherapy, monolumen and bilumen catheters, days of catheterization, immunosuppression, kidney disease and diabetes mellitus) due to the homogeneity of their definitions and measurements. The risk factors found to increase the probability of developing CLABSI were TPN, multilumen devices, chemotherapy treatment, immunosuppression and the number of days of catheterization. On the other hand, monolumen devices presented a lower likelihood of triggering this infection.
Glycemic control and diabetes complications among adult type 2 diabetic patients at public hospitals in Hadiya zone, Southern Ethiopia
Authors: Dimore Abraham Lomboro , Edosa Zerihun Kura , Mitiku Asmelash Abera 
Published: March 2023

Background
Diabetes is one of the biggest worldwide health emergencies of the 21st century. A major goal in the management of diabetes is to prevent diabetic complications that occur as a result of poor glycemic control. Identification of factors contributing to poor glycemic control is key to institute suitable interventions for glycemic control and prevention of chronic complications.

Methods
A hospital-based cross-sectional study was conducted among 305 adult type 2 diabetic patients at public hospitals in Hadiya zone from March 1–30, 2019. The study participants were selected by systematic sampling technique. Data were collected using a pretested structured questionnaire and patient chart review; anthropometric and blood pressure measurements were taken. Multivariable logistic regression analysis was used to identify factors associated with poor glycemic control. Adjusted odds ratios (AOR) with respective 95% Confidence Interval (CI) and p < 0.05 were used to set statistically significant variables.

Results
Out of 305 diabetic patients, 222 (72.8%) were found to have poor glycemic control. Longer duration of diabetes (5–10 years) [AOR = 2.24, 95% CI: 1.17–4.27], lack of regular follow-up [AOR = 2.89, 95% CI: 1.08–7.71], low treatment adherence [AOR = 4.12, 95% CI: 1.20–8.70], use of other alternative treatments [AOR = 3.58, 95% CI: 1.24–10.36], unsatisfactory patient physician relationship [AOR = 2.27, 95% CI: 1.27–4.04], and insufficient physical activity [AOR = 4.14, 95% CI: 2.07–8.28] were found to be independent predictors of poor glycemic control. Diabetes Mellitus (DM) complications were slightly higher among participants with poor glycemic control (39.2%), duration of DM 10 and above years (41.9%), low medication adherence (48.5%), taking oral anti-diabetics (54.3%), and DM patients having unsatisfactory patient provider relationship (72.4%).

Conclusion
A significant proportion of diabetic patients had poor glycemic control and DM complications. Therefore, appropriate interventions are required to maintain optimal glycemic control and prevent the development of life-threatening complications among DM patients.
Chlorhexidine bathing in a tertiary care neonatal intensive care unit: A pilot study
Authors: Bar-Meir Maskit , Bendelac Shoshana , Shchors Irina 
Published: March 2023

Background
Concerns regarding potential risk of dermal irritation have led to the exclusion of NICU patients from the recommendation regarding the use of 2% chlorhexidine gluconate (CHG) wash for daily skin cleansing to reduce bloodstream infections. Our aim was to assess the safety of 2% CHG bathing in NICU patients.

Methods
The regulator required a stepwise study enrollment to three successive groups: term infants, followed by near-term and pre-term infants. For comparison, we used a cohort of matched controls. A propensity score-adjusted regression model was used to compare the groups.

Intervention
Infants were bathed thrice-weekly with 2% CHG-impregnated washcloths. Participant’s skin was examined daily.

Results
Over a total of 661 days of treatment: 384,129, and 148 days for the term, near-term and pre-term groups, respectively, no skin reactions were observed. The intervention group was generally sicker, however, bloodstream infections were similar between the groups.

Conclusion
For infants >30 weeks and >3 days old, 2% CHG bathing was safe. Large multicenter studies are urgently needed to establish the effectiveness of this practice in the NICU.
Prevalence of depression and its association with health-related quality of life in people with heart failure in low- and middle-income countries: A systematic review and meta-analysis
Authors: Mulugeta Henok , Sinclair Peter M. , Wilson Amanda 
Published: March 2023

Introduction
Heart failure is a growing public health concern around the world. People with heart failure have a high symptom burden, such as depression, which affects health-related quality of life (HRQoL). The objective of this systematic review and meta-analysis was to estimate the pooled prevalence of depression and evaluate its association with HRQoL among people with heart failure in low- and middle-income countries (LMICs).

Methods
This systematic review was conducted in accordance with the JBI methodology. Electronic databases such as MEDLINE, PsycINFO, EMBASE, CINAHL, Web of Science, Scopus and JBI EBP were searched to identify relevant studies published from January 2012 to August 2022. The methodological quality of each article was assessed using relevant JBI critical appraisal instruments. A random-effects model was employed to estimate the pooled prevalence of depression. Heterogeneity across the studies was investigated using Cochrane’s Q test and I2 statistic. The Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines 2020 were followed for reporting the results. All statistical analyses were performed using STATA version 17 software.

Results
After screening, a total of 21 eligible articles with 5074 participants with heart failure were included in this review. The pooled prevalence of depression among people with heart failure in LMICs was 51.5% (95% CI = 39.7, 63.3%, I2 = 99.00%). Subgroup analysis revealed, the highest prevalence in studies whose participants were in-patients, and from the Middle East and North Africa, and studies utilizing Becks Depression Inventory (BDI). Depression was positively associated with HRQoL.

Conclusion
This review revealed that almost half of all people with heart failure in low- and middle-income countries have comorbid depression. People with heart failure and depressive symptoms had poor HRQoL. Therefore, early screening of depression is critical for improving HRQoL in this population.
Systematic review registration: PROSPERO CRD42022361759.
Investment case for primary health care in low- and middle-income countries: A case study of Kenya
Authors: Mwai Daniel , Hussein Salim , Olago Agatha , Kimani Maureen , Njuguna David , Njiraini Rose , Wangia Elizabeth , Olwanda Easter , Mwaura Lilian , Rotich Wesley 
Published: March 2023

Background
Primary healthcare (PHC) systems attain improved health outcomes and fairness and are affordable. However, the proportion of PHC spending to Total Current Health Expenditure in Kenya reduced from 63.4% in 2016/17 to 53.9% in 2020/21 while external funding reduced from 28.3% (Ksh 69.4 billion) to 23.9% (Ksh 68.2 billion) over the same period. This reduction in PHC spending negatively affects PHC performance and the overall health system goals.

Methods
We conducted a cost-benefit analysis and computed costs against the economic benefits of a PHC scale-up. Activity-Based Costing (ABC) on the provider perspective was employed to estimate the incremental costs. The OneHealth Tool was used to estimate the health impact of operationalizing PHC over five years. Finally, we quantified Return on Investment (ROI) by estimating monetized DALYs based on a constant value per statistical life year (VSLY) derived from a VSL estimate.

Results
The total projected cost of PHC interventions in the Kenya was Ksh 1.65 trillion (USD 15,581.91 billion). Human resource was the main cost driver accounting for 75% of the total cost. PHC investments avert 64,430,316 Disability Adjusted Life-Years (DALYs) and generate cost savings of Ksh. 21.5 trillion (USD 204.4 Billion) over five years. Shifting services from high-level facilities to PHC facilities generates Ksh 198.2 billion (USD 1.9 billion) and yields a benefit-cost ratio of 16:1 in 5 years. Thus, every $1 invested in PHC interventions saves up to $16 in spending on conditions like stunting, NCDs, anaemia, TB, Malaria, and maternal and child health morbidity.

Conclusions
Evidence of the economic benefits of continued prioritization of funding for PHC can strengthen the advocacy argument for increased domestic and external financing of PHC in Kenya. A well-resourced and functional PHC system translates to substantial health benefits with positive economic benefits. Therefore, governments and stakeholders should increase investments in PHC to accelerate economic growth.
Modifiable and nonmodifiable factors associated with anxiety, depression, and stress after one year of the COVID-19 pandemic
Authors: Islam Azharul , Mahbuba Papia , Ahmed Tanvir , Haque Shamsul 
Published: March 2023

Background
People worldwide have experienced various mental health issues during the COVID-19 pandemic. This study investigates the modifiable and nonmodifiable predictors of anxiety, depression, and stress among Bangladeshi participants after one year of the pandemic.

Method
A large group of adult participants (N = 1897), recruited from eight administrative divisions in Bangladesh, completed an online survey in May and June 2021 when the Movement Control Order was in place. We used the Beck Anxiety Inventory, Patient Health Questionnaire-9, and Perceived Stress Scale-4 to assess the participants’ anxiety, depression, and stress. We also gave the Mindful Attention Awareness Scale and Life-Orientation Test-Revised to assess mindfulness and optimism.

Results
The results revealed that the prevalence rates for anxiety and depression were 62.5% and 45.3%, respectively. Multivariate analyses showed that several nonmodifiable factors, such as those who were students, unmarried and females, and those living in the Northern region (Rajshahi and Mymensingh division) and dwelling in the rural areas, suffered from worse mental health (accounted for 5%-23% of the variances in the mental health outcome scores). Modifiable factors accounted for an additional 10%-25% of the variances in the same outcome variables. Adults with higher mindfulness and optimism, living in the country’s Southern region (Chattogram division) and those who took both vaccine doses and had no history of mental illness reported better mental health.

Conclusion
Anxiety, depression, and stress remained high in Bangladeshi adults after one year of the pandemic. The community-based interventions should aim to increase the mindfulness and optimism levels among the sufferers. More accelerated vaccination programs across the country could protect people from suffering from overall mental distress.
Association between proximity to COVID-19 and the quality of life of healthcare workers
Authors: Khaing Nang Ei Ei , Quah Claire , Png Gek Kheng , Wong Joanna , Tee Augustine , Oh Hong Choon 
Published: March 2023

BackgroundThe coronavirus disease 2019 (COVID-19) affects almost all countries in the world and it impacts every aspect of people’s life-physically, mentally, and socio-economically. There are several research studies examining the impact of this pandemic on health, however, very few studies examining the impact of this pandemic on quality of life. This study aimed to investigate the association between proximity to the COVID-19 and quality of life of healthcare workers and identify factors influencing quality of life.MethodsA cross-sectional study was conducted among hospital staff in a tertiary hospital in Singapore. Data on demographic, medical history, lifestyle factors, psychosocial factors, and quality of life were collected using online self-administered questionnaire. Quality of life (QoL) was measured by the WHOQOL-BREF questionnaire. Robust linear regression was used to determine factors associated with quality of life.ResultsA total of 1911 participants were included in the analysis. The average age of participants was 38.25 (SD = 11.28) years old. 26.90% of participants had been quarantined, hospitalised, being suspected or diagnosed of having COVID-19 infection and they were found to have the lowest levels of QoL across all four domains (physical, psychological, social, and environmental domains). Participants who were singles or nurses, worked in shifts or worked longer hours, had chronic diseases were likely to have lower QoL scores compared to participants in other categories. Healthy lifestyle, social connectivity, resilience, social and workplace support were associated with higher QoL scores.ConclusionsIn planning of measures which aim to improve QoL of healthcare workers, priority should be given to individuals who have been quarantined, hospitalised, being suspected, or diagnosed of having COVID-19 infection. In addition to the proximity of the COVID, lifestyle and psychosocial factors contribute to QoL of healthcare workers. Hence, multifaceted interventions are needed to improve QoL of healthcare workers.
Un análisis multicriterio para la toma de decisiones en la selección de una mezcla asfáltica en pavimentos
Authors: Sánchez Edgar , Villegas Flores Noé , Ochoa Averos Sara del Rocío , Saldeño Madero Yelinca Nalena 
Published: March 2023

Objetivo: Esta investigación presenta una novedosa metodología multicriterio que permite evaluar dos materiales asfálticos utilizados en el sector de la pavimentación, en aras de aportar directrices al momento de seleccionar un material bajo un perfil sostenible. Esta herramienta metodológica permite evaluar características e indicadores asociados al comportamiento de una mezcla asfáltica de forma integrada, consistente y con impacto medioambiental.
Metodología: Se obtuvo un parámetro de sostenibilidad asociado al estudio de dos materiales del sector de la pavimentación. Se evaluaron las principales características de una mezcla asfáltica en caliente y una mezcla fría bajo las mismas condiciones de contorno. Con respecto al modelo multicriterio, se tomó el concepto de teoría de la decisión, con apoyo de la metodología MIVES y la función de utilidad, permitiendo evaluar y comparar los indicadores propuestos para este caso de análisis.
Resultados: Se obtuvo el índice de sostenibilidad para los dos materiales estudiados. La mezcla asfáltica fría obtuvo un valor de 0,76, representando de forma global un mejor desempeño en los tres ejes analizados (medioambiental, económico y de operación). Por otro lado, la mezcla en caliente obtuvo un índice de 0,57, valor inherente a una respuesta menos positiva que la mezcla fría.
Conclusiones: La metodología desarrollada permitió incorporar variables e indicadores con unidades de medición distintas y de naturaleza diversa. La obtención de un índice de sostenibilidad en materiales asfálticos supone un avance significativo en la aplicación de metodologías multicriterio.
Etična občutljivost študentov zdravstvene nege
Authors: Renko Jakob , Praprotnik Deja , Nastran Ana , Prosen Mirko , Ličen Sabina 
Published: March 2023

Uvod: Etična občutljivost je pomemben dejavnik pri zagotavljanju kakovostne zdravstvene oskrbe. Namen raziskave je bil preučiti etično občutljivost študentov zdravstvene nege.Metode: Uporabljena je bila kvantitativna metodologija raziskovanja z metodo anketiranja. Anketiranje je potekalo na priložnostnem vzorcu 126 dodiplomskih študentov zdravstvene nege. Podatki so bili zbrani na podlagi prevedenega in prilagojenega »Vprašalnika za merjenje etične občutljivosti med študenti zdravstvene nege« (ang. Ethical Sensitivity Questionnaire for Nursing Students). Za statistično analizo so bile uporabljene naslednje metode: osnovna deskriptivna statistika ter neparametrični Mann-Whitneyjev U-test in Kruskal- Wallisov H-test.Rezultati: Rezultat notranje konsistentnosti za celoten vprašalnik je pokazal dobro stopnjo zanesljivosti (Cronbach α = 0,711). Anketirani študenti zdravstvene nege na dodiplomskem študiju so prikazali zmerno stopnjo etične občutljivosti ( = 33,50, s = 5,615). Rezultati so pokazali statistično značilne razlike v stopnji etične občutljivosti med rednimi študenti dodiplomskega študija zdravstvene nege in študenti izrednega študija (p = 0,025).Diskusija in zaključek: Ugotovljeno je bilo, da obstajajo možnosti za izboljšanje etične občutljivosti študentov zdravstvene nege. Na podlagi ugotovitev so potrebne nadaljnje raziskave o etični občutljivosti v povezavi z delovno otopelostjo v zdravstvenem sistemu. Smiselno bi bilo raziskati tudi dejavnike, ki vplivajo na etično občutljivost in primerjati etično občutljivost med študenti zdravstvene nege in zaposlenimi medicinskimi sestrami.
PERBEDAAN FAKTOR RISIKO STUNTING DI DAERAH PERKOTAAN DAN PERDESAAN PADA ANAK USIA 6-23 BULAN DI INDONESIA: ANALISIS DATA RISKESDAS
Authors: Ucianna Vivi , Pramono Adriyan , Margawati Ani , Syauqy Ahmad 
Published: March 2023

Latar belakang: Stunting merupakan masalah gizi yang sering ditemukan di negara berkembang, termasuk Indonesia. Stunting dapat disebabkan oleh banyak faktor. Perbedaan tempat tinggal di perkotaan dan perdesaan salah satu faktor penyebab stunting. Tujuan: Menganalisis faktor risiko stunting di daerah perkotaan dan perdesaan pada anak usia 6-23 bulan di Indonesia.Metode: Penelitian ini menggunakan desain cross-sectional dengan menganalisis data survei nasional di 34 provinsi di Indonesia tahun 2018 (Riskesdas 2018). Jumlah subjek dalam penelitian ini sebanyak 15.833 anak usia 6-23 bulan. Data dianalisis menggunakan analisis deskriptif, uji chi-square, dan regresi logistik ganda.Hasil: Prevalensi stunting pada usia 6-23 bulan lebih rendah di perkotaan (26,9%) dibandingkan di perdesaan (30,8%). Perbedaan signifikan yang ditemukan pada faktor risiko kejadian stunting antara daerah perkotaan dan perdesaan. Faktor risiko kejadian stunting yang signifikan di perkotaan adalah berat badan lahir rendah (OR=2,017, 95%Cl: 1,655-2,457). Sedangkan, faktor risiko kejadian stunting yang signifikan di perdesaan adalah adalah kelahiran prematur (OR=1,121, 95%Cl: 1,015–1,238) dan riwayat berat badan lahir rendah (OR=2,188, 95%Cl: 1,845–2,595). Setelah dikontrol dengan variable perancu (jenis kelamin dan usia), berat badan lahir rendah (OR=2,017, 95%Cl: 1,655-2,457) tetap menjadi faktor risiko kejadian stunting yang signifikan di perkotaan. Sedangkan, kelahiran prematur (OR=1,121, 95%Cl: 1,015–1,238) dan riwayat berat badan lahir rendah (OR=2,188, 95%Cl: 1,845–2,595) juga tetap menjadi faktor risiko kejadian stunting yang signifikan di perdesaanSimpulan: Berat badan lahir rendah menjadi faktor risiko stunting di daerah perkotaan dan perdesaan. Sedangkan, kelahiran premature menjadi faktor risiko stunting hanya di perdesaan.
The assessment of cortical hemodynamic responses induced by tubuloglomerular feedback using in vivo imaging
Authors: Lee Blaire , Postnov Dmitry D. , Sørensen Charlotte M. , Sosnovtseva Olga 
Published: March 2023

AbstractThe tubuloglomerular feedback (TGF) mechanism modulates renal hemodynamics and glomerular filtration rate in individual nephrons. Our study aimed to evaluate the TGF‐induced vascular responses by inhibiting Na‐K‐2Cl co‐transporters and sodium‐glucose co‐transporters in rats. We assessed cortical hemodynamics with high‐resolution laser speckle contrast imaging, which enabled the evaluation of blood flow in individual microvessels and analysis of their dynamical patterns in the time‐frequency domain. We demonstrated that a systemic administration of furosemide abolishes TGF‐mediated hemodynamic responses. Furthermore, we showed that the local microcirculatory blood flow decreased, and the TGF‐induced hemodynamic oscillations were sustained but weakened after inhibiting sodium‐glucose co‐transporters in Sprague–Dawley rats.