bluuebunny/crossref_metadata_2025_split huggingface dataset:
White Racial Identity, Racial Attitudes, and Latino Partisanship
Authors: Cuevas-Molina Ivelisse 
Published: September 2023

AbstractWhile partisanship in American politics has been historically tied to racial identity and racial attitudes, most studies of Latino partisanship do not incorporate these factors into understanding their partisan attachments. I argue that the concepts of race, color, and mestizaje as they are understood within Latino communities in the United States can influence political attitudes and partisanship among Latinos themselves. Using six consecutive Cooperative Election Study (formerly Cooperative Congressional Election Study) surveys I examine how self-identification as white, racial resentment, and color-blind attitudes influence Latino partisanship. I find that white racial identity has a small but significant positive association with Republican partisanship among Latinos, and a negative association with Democratic partisanship. Additionally, negative racial attitudes among Latinos are strongly related to identification as Republican, even when controlling for ideology and other factors like immigrant generation and religion. These results have important implications for understanding current and future Latino voting patterns.
Expression patterns and antifungal function study of KaSPI in Mythimna separata
Authors: Chen Ya-Ru , Yang Hong-Jia , Cha Jin-Myong , Zhang Xin-Xin , Fan Dong 
Published: September 2023

AbstractKazal-type serine protease inhibitors (KaSPI) play important roles in insect growth, development, digestion, metabolism and immune defence. In this study, based on the transcriptome of Mythimna separata, the cDNA sequence of MsKaSPI with Kazal domain was uploaded to GenBank (MN931651). Spatial and temporal expression analysis showed that MsKaSPI was expressed at different developmental stages and different tissues, and it was induced by 20-hydroxyecdysone in third-instar larvae of M. separata. After 24 h infection by Beauveria bassiana, the expression level of MsKaSPI and the corresponding MsKaSPI content were significantly up-regulated, being 6.42-fold and 1.91-fold to the control group, respectively, while the activities of serine protease, trypsin and chymotrypsin were inhibited. After RNA interference interfered with MsKaSPI for 6 h, the expression decreased by 73.44%, the corresponding content of MsKaSPI protein decreased by 55.66% after 12 h, and the activities of serine protease and trypsin were significantly enhanced. Meanwhile, both the larval and pupal stages of M. separata were prolonged, the weights were reduced and the number of eggs per female decreased by 181. Beauveria bassiana infection also increased the mortality of MsKaSPI-silenced M. separata by 18.96%. These prove MsKaSPI can not only result in slow growth and low fecundity of M. separata by regulating the activity of related protease, but also participate in the resistance to pathogenic fungi by regulating the serine protease inhibitor content and the activities of related serine protease.
Jesus’s Secret Journey in John 7: A Symbol of the Ascension
Authors: Méndez Hugo 
Published: September 2023

AbstractIn John 7:8–9, Jesus tells his brothers he will not “go up” to Jerusalem, but in the very next scene, he makes the ascent in secret. This essay interprets Jesus’s unusual, and seemingly deceptive, behavior in the episode as a symbolic action akin to others structuring the first half of the Gospel. The episode immediately precedes a dialogue in which Jesus predicts his imminent departure from the world. Jesus insists that he will soon “go” to God so that unbelievers “will seek” him “but … not find” him (7:33–34; cf. 20:17). Foreshadowing this future, Jesus “goes up” to Judea but in such a way that leaves unbelievers unaware of his whereabouts, leaving them to ask, “Where is he?” (7:10–11). The article highlights half-truth as an important speech device in the episode and dialogue that follows. It also concludes that the episode is key to interpreting other scenes sharing a motif of misdirection, delay, and secret reversal.
Seasonal dietary niche changes in Neotropical bats
Authors: Genelhú Sebastião Maximiano Corrêa , Laurindo Rafael de Souza , Tahara Arthur Setsuo , Oliveira Letícia Langsdorff , Gregorin Renato 
Published: September 2023

Abstract
In the vast Neotropic seasonal environment, the most diverse family of bats, the Phyllostomidae (leaf-nosed bats), includes up to 93 species. As the quality and quantity of food resources fluctuate in the habitats, diet heterogeneity is observed among bat species and regions of the Neotropics. In this study, we investigated by faecal analyses, how the dietary niche (DN) of eight Phyllostomidae bat species (Artibeus planirostris, A. fimbriatus, Carollia brevicauda, C. perspicillata, Chiroderma villosum, Glossophaga soricina, Platyrrhinus lineatus, and Sturnira lilium) that occur in a karstic area in the Midwest region of Minas Gerais, Brazil, change in response to seasonal food availability. We recorded the consumption of insects and nine plant families. Moraceae was the most frequent, followed by Piperaceae. Given that seasonal dietary changes can be subtle and hardly noticeable along with fluctuating habitat conditions, we performed the DN decomposition of the eight bats species into subniches, by analysing the data with the WitOMI, which is a decomposition of the niche into temporal subniches. By improving the accuracy and details of the results, we assessed the effects of abiotic (precipitation and environmental temperature) and biotic (quantity and quality of food resources) interactions within the phyllostomid bat community. For each species, we compared niche breadth and overlap and found higher values for the dry season among morphologically similar species. The results of our study suggest that ecologically similar bat species coexist occupying different DNs.
Hydrocarbons on Mars
Authors: Klokočník Jaroslav , Kostelecký Jan , Bezděk Aleš , Cílek Václav 
Published: September 2023

AbstractProviding evidence for possible oil-type occurrences on Mars means providing an indication for the past life on Mars. We do this via analysis of the combed (aligned) gravity strike angles, one of the gravity (gravitational) aspects (descriptors) derived from one of the recent gravitational field models of Mars, currently having the highest accessible precision and resolution. After intensive testing for features on the Earth and the Moon, the gravity aspects are applied for Mars. We detect candidates for the groundwater/hydrocarbon/mud/petroleum-bearing sites in the largest areas with as many as possible combed gravity strike angles, uniformly ordered into ‘plates’. They appear mainly but not only in the hypothetical northern Martian palaeo-ocean (the northern lowlands). It turns out that the combed strike angles are sensitive not only to uniformly ordered sediments of the basins, but also to supposed lahars.
Global Surface Winds and Aeolian Sediment Pathways on Mars From the Morphology of Barchan Dunes
Authors: Rubanenko L. , Gunn A. , Pérez‐López S. , Fenton L. K. , Ewing R. C. , Soto A. , Lapôtre M. G. A. 
Published: September 2023

AbstractIn the absence of consistent meteorological data on Mars, the morphology of dunes can be employed to study its atmosphere. Specifically, barchan dunes, which form under approximately unimodal winds, are reliable proxies for the dominant wind directions. Here, we characterize near‐surface winds on Mars from the morphology of >700,000 barchans mapped globally on the planet by a convolutional neural network. Barchan migration is predominantly aligned with known southern‐summer atmospheric circulation patterns—northerly at mid‐latitudes and cyclonic near the north pole—with the addition of an anti‐cyclonic north‐polar component that likely originates from winds emerging from the ice cap. Locally, migration directions deviate from regional trends in areas with high topographic roughness. Notably, obstacles <100 km such as impact craters are efficient at deflecting surface winds. Our database, which provides insights into planetary‐scale aeolian processes on modern‐day Mars, can be used to constrain global circulation models to assist with predictions for future missions.
Reply to “Comment on ‘Advanced Testing of Low, Medium, and High ECS CMIP6 GCM Simulations Versus ERA5‐T2m’ by N. Scafetta (2022)” by Schmidt et al. (2023)
Authors: Scafetta Nicola 
Published: September 2023

AbstractSchmidt, Jones, and Kennedy’s (SJK) (2023, https://doi.org/10.1029/2022GL102530) critique of Scafetta (2022, https://doi.org/10.1029/2022GL097716) is flawed. Their assessment of the error of the ERA‐T2m 2011–2021 mean (≈0.10°C) is 5–10 times overestimated and contradicts published literature. SJK confused natural variability with random noise and mistook the error of the mean of a temperature chronology for the stochastic error of the regression parameter M of a nonphysical isothermal climate model (T(t) = M). SJK's allegations regarding the internal variability of the models, the role of the global climate model ensemble members, and other issues were partially addressed in Scafetta (2022, https://doi.org/10.1029/2022GL097716) and, later, more extensively in Scafetta (2023a, https://doi.org/10.1007/s00382-022-06493-w) where Scafetta's (2022, https://doi.org/10.1029/2022GL097716) conclusions were confirmed.
Groundwater Flooding on Atolls Caused by Storm Surges: Effects of the Dual‐Aquifer Configuration
Authors: Tajima Satoshi , Brunner Philip , Liu Jiaqi , Delottier Hugo , Tokunaga Tomochika 
Published: September 2023

AbstractStorm surges associated with tropical cyclones endanger atolls through groundwater flooding, where groundwater is discharged from the land surface as the sea level rises. Atolls are characterized by a “dual‐aquifer” configuration, where recent Holocene sediments unconformably overlie highly permeable Pleistocene limestone, creating an interface called a “Thurber discontinuity.” This study aimed to quantitatively analyze how the dual‐aquifer configuration of atolls controls the temporal dynamics of groundwater flooding caused by storm surge. To this end, we ran surface‐subsurface coupled synthetic numerical simulations using HydroGeoSphere and compared 12 scenarios with different Thurber discontinuity elevations and hydraulic conductivities of the Pleistocene aquifer (KP). The results showed that the shallower the Thurber discontinuity and the higher the KP value, the higher the maximum water depth in the freshwater swamp on the atoll during the storm surge and the longer the flooding duration. Despite the effects of the different dual‐aquifer configurations, the initial water table elevation and salinity distribution were almost identical in all the simulation cases. These findings suggest that accurate information on the dual‐aquifer configuration is necessary to evaluate the potential risk of groundwater flooding on atolls accompanying storm surges. Furthermore, the results indicate that groundwater flooding caused by storm surges substantially contributes to cyclone‐driven flooding on atolls, and hence, it should not be neglected in flood predictions to avoid underestimation.
Targeting ferroptosis opens new avenues for the development of novel therapeutics
Authors: Sun Shumin , Shen Jie , Jiang Jianwei , Wang Fudi , Min Junxia 
Published: September 2023

AbstractFerroptosis is an iron-dependent form of regulated cell death with distinct characteristics, including altered iron homeostasis, reduced defense against oxidative stress, and abnormal lipid peroxidation. Recent studies have provided compelling evidence supporting the notion that ferroptosis plays a key pathogenic role in many diseases such as various cancer types, neurodegenerative disease, diseases involving tissue and/or organ injury, and inflammatory and infectious diseases. Although the precise regulatory networks that underlie ferroptosis are largely unknown, particularly with respect to the initiation and progression of various diseases, ferroptosis is recognized as a bona fide target for the further development of treatment and prevention strategies. Over the past decade, considerable progress has been made in developing pharmacological agonists and antagonists for the treatment of these ferroptosis-related conditions. Here, we provide a detailed overview of our current knowledge regarding ferroptosis, its pathological roles, and its regulation during disease progression. Focusing on the use of chemical tools that target ferroptosis in preclinical studies, we also summarize recent advances in targeting ferroptosis across the growing spectrum of ferroptosis-associated pathogenic conditions. Finally, we discuss new challenges and opportunities for targeting ferroptosis as a potential strategy for treating ferroptosis-related diseases.
Spatiotemporal, optogenetic control of gene expression in organoids
Authors: Legnini Ivano , Emmenegger Lisa , Zappulo Alessandra , Rybak-Wolf Agnieszka , Wurmus Ricardo , Martinez Anna Oliveras , Jara Cledi Cerda , Boltengagen Anastasiya , Hessler Talé , Mastrobuoni Guido , Kempa Stefan , Zinzen Robert , Woehler Andrew , Rajewsky Nikolaus 
Published: September 2023

AbstractOrganoids derived from stem cells have become an increasingly important tool for studying human development and modeling disease. However, methods are still needed to control and study spatiotemporal patterns of gene expression in organoids. Here we combined optogenetics and gene perturbation technologies to activate or knock-down RNA of target genes in programmable spatiotemporal patterns. To illustrate the usefulness of our approach, we locally activated Sonic Hedgehog (SHH) signaling in an organoid model for human neurodevelopment. Spatial and single-cell transcriptomic analyses showed that this local induction was sufficient to generate stereotypically patterned organoids and revealed new insights into SHH’s contribution to gene regulation in neurodevelopment. With this study, we propose optogenetic perturbations in combination with spatial transcriptomics as a powerful technology to reprogram and study cell fates and tissue patterning in organoids.
Fast and robust metagenomic sequence comparison through sparse chaining with skani
Authors: Shaw Jim , Yu Yun William 
Published: September 2023

AbstractSequence comparison tools for metagenome-assembled genomes (MAGs) struggle with high-volume or low-quality data. We present skani (https://github.com/bluenote-1577/skani), a method for determining average nucleotide identity (ANI) via sparse approximate alignments. skani outperforms FastANI in accuracy and speed (>20× faster) for fragmented, incomplete MAGs. skani can query genomes against >65,000 prokaryotic genomes in seconds and 6 GB memory. skani unlocks higher-resolution insights for extensive, noisy metagenomic datasets.
Aberrant gene activation in synovial sarcoma relies on SSX specificity and increased PRC1.1 stability
Authors: Benabdallah Nezha S. , Dalal Vineet , Scott R. Wilder , Marcous Fady , Sotiriou Afroditi , Kommoss Felix K. F. , Pejkovska Anastasija , Gaspar Ludmila , Wagner Lena , Sánchez-Rivera Francisco J. , Ta Monica , Thornton Shelby , Nielsen Torsten O. , Underhill T. Michael , Banito Ana 
Published: September 2023

AbstractThe SS18-SSX fusion drives oncogenic transformation in synovial sarcoma by bridging SS18, a member of the mSWI/SNF (BAF) complex, to Polycomb repressive complex 1 (PRC1) target genes. Here we show that the ability of SS18-SSX to occupy H2AK119ub1-rich regions is an intrinsic property of its SSX C terminus, which can be exploited by fusion to transcriptional regulators beyond SS18. Accordingly, SS18-SSX recruitment occurs in a manner that is independent of the core components and catalytic activity of BAF. Alternative SSX fusions are also recruited to H2AK119ub1-rich chromatin and reproduce the expression signatures of SS18-SSX by engaging with transcriptional activators. Variant Polycomb repressive complex 1.1 (PRC1.1) acts as the main depositor of H2AK119ub1 and is therefore required for SS18-SSX occupancy. Importantly, the SSX C terminus not only depends on H2AK119ub1 for localization, but also further increases it by promoting PRC1.1 complex stability. Consequently, high H2AK119ub1 levels are a feature of murine and human synovial sarcomas. These results uncover a critical role for SSX-C in mediating gene deregulation in synovial sarcoma by providing specificity to chromatin and further enabling oncofusion binding by enhancing PRC1.1 stability and H2AK119ub1 deposition.
Condition optimization of eco-friendly RP-HPLC and MCR methods via Box–Behnken design and six sigma approach for detecting antibiotic residues
Authors: Y. A. Alanazi Tahani , Adel Pashameah Rami , Y. Binsaleh Ammena , A. Mohamed Mahmoud , A. Ahmed Hoda , F. Nassar Hossam 
Published: September 2023

AbstractA precise, Eco-friendly, and highly sensitive RP-HPLC method was employed using quality-by-design principles to concurrently identify cephalexin and cefixime residues in the manufacturing machines using a hypersil BDS C18 column (250 × 4.6 mm, 5 μm) at wavelength 254 nm. The Box–Behnken design was applied to obtain the best chromatographic conditions with the fewest possible trials. Three independent factors viz organic composition, flow rate, and pH were used to assess their effects on the responses' resolution and retention time. Overlay plot and desirability functions were implemented to predict responses of the high resolution and relatively short retention time using a mobile phase composed of acidic water: acetonitrile (85:15, v/v) at pH 4.5 adjusted by phosphoric acid with a flow rate of 2.0 mL/min. The spectral overlapping of the drugs was successfully resolved by the mean centering ratio (MCR) spectra approach at 261 nm and 298 nm for cephalexin and cefixime, respectively. Good linearity results were obtained for the suggested HPLC and MCR methods over the concentration range of (0.05–10 ppm) and (5–30 ppm) with a detection limit of 0.003, 0.004, 0.26, and 0.23 ppm, and quantitation limits of 0.008, 0.013, 0.79, and 0.68 ppm for cephalexin and cefixime, respectively, with a correlation coefficient of ≥ 0.9998 and good swab recovery results of 99–99.5%. A process capability index was accomplished for chemical and micro results, illustrating that both are extremely capable. The suggested method was effectively validated using ICH recommendations.
Behavior of non-prismatic RC beams with conventional steel and green GFRP rebars for sustainable infrastructure
Authors: Suparp Suniti , Khan Inamullah , Ejaz Ali , Khan Kaffayatullah , Weesakul Uruya , Hussain Qudeer , Saingam Panumas 
Published: September 2023

AbstractThis study presents an experimental and finite element analysis of reinforced concrete beams with solid, hollow, prismatic, or non-prismatic sections. In the first part, a total of six beams were tested under four-point monotonic bending. The test matrix was designed to provide a comparison of structural behavior between prismatic solid and hollow section beams, prismatic solid and non-prismatic solid section beams, and prismatic hollow and non-prismatic hollow section beams. The intensity of shear was maximum in the case of prismatic section beams. The inclusion of a tapered section lowered the demand for shear. In the second part, Nonlinear Finite Element Modeling was performed by using ATENA. The adopted modeling strategy resulted in close agreement with experimental crack patterns at ultimate failure. However, the ultimate failure loads predicted by nonlinear modeling were generally higher than their corresponding experimental results. Whereas in the last part, the developed models were further extended to investigate the effect of the strength of concrete and ratio of longitudinal steel bars on the ultimate load-carrying capacity and cracking behavior of the reinforced concrete beams with solid, hollow, prismatic, or non-prismatic sections. The ultimate loads for each beam predicted by the model were found to be in close agreement with experimental results. Nonlinear modeling was further extended to assess the effects of concrete strength and longitudinal reinforcement ratio on failure patterns and ultimate loads. The parametric study involved beams reinforced with glass fiber-reinforced polymer (GFRP) bars against shear and flexural failure. In terms of ultimate load capacities, diagonal cracking, and flexural cracking, beams strengthened with GFRP bars demonstrated comparable performance to the beams strengthened with steel bars.
First report of environmental isolation of Cryptococcus and Cryptococcus-like yeasts from Boyacá, Colombia
Authors: Serna-Espinosa Briggith-Nathalia , Forero-Castro Maribel , Morales-Puentes María Eugenia , Parra-Giraldo Claudia Marcela , Escandón Patricia , Sánchez-Quitian Zilpa Adriana 
Published: September 2023

AbstractThe Cryptococcus genus comprises more than 100 species, of which C. neoformans and C. gattii are the leading cause of cryptococcosis. The distribution of C. gattii and C. neoformans species complexes has been extensively studied and widely reported globally. Other species such as Naganishia albida, Papiliotrema laurentii, and Papiliotrema flavescens have been reported as pathogenic yeasts. Since there are no reports of environmental isolation in the Boyacá region (Colombia), this study aimed to isolate and characterize Cryptococcus and Cryptococcus-like yeasts from pigeon feces, Eucalyptus, and olive trees distributed in the municipalities of Tunja and Ricaute Alto. The environmental data was recovered, and the isolations obtained were identified by microscopy, biochemical test, MALDI-TOF MS, URA5-RFLP, and sequencing of the ITS and LSU loci. For the 93 pigeon dropping samples collected in Tunja, 23 yielded to C. neoformans, 3 to N. globosa, 2 N. albida and 1 to P. laurentii. Of the 1188 samples collected from olive trees, 17 (1.43%) positive samples were identified as C. gattii species complex (4), C. neoformans species complex (2), P. laurentii (3), N. albida (2), N. globosa (5) and P. flavescens (1). Likewise, specimens of C. neoformans presented molecular type VNI and molecular type VNII; for C. gattii the molecular types found were VGIII and one VGIV by URA5-RFLP but VGIII by MALDI-TOF and sequencing of the ITS and LSU. Therefore, it can be concluded that the species of Cryptococcus, Naganishia and Papiliotrema genera, are present in the environment of Boyacá, and show a predilection for climate conditions that are typical of this region.
Qualitative study of the association between psychosocial health and physical activity/sleep quality in toddlers
Authors: Tsuyuki Chisa , Suzuki Koya , Seo Kanako , Ke Dandan , Tsuge Kyoko , Deng Pengyu , Lu Dajiang , Naito Hisashi 
Published: September 2023

AbstractPhysical activity and sleep are important factors of mental and physical health in children, with some reports indicating that their effects can persist into adulthood. However, there is limited research on the qualitative aspects of physical activity and sleep in preschool children, particularly in those aged < 3 years. Therefore, to elucidate the association between psychosocial health and physical activity/sleep in early childhood in terms of qualitative aspects, we conducted a retrospective cohort study in 2985 3-year-old children (37.2 ± 0.75 months) in Shanghai, China. An analysis using structural equation modeling indicated that current physical activity had a direct and moderate impact on current psychosocial health evaluated using the Strength and Difficulties Questionnaire. In particular, past physical activity had an indirect and mild effect on current psychosocial health via current physical activity in girls. However, regardless of sex, past sleep quality had slight impact on current psychosocial health, not only indirectly via current sleep quality, but also directly. These findings highlight the importance of considering the qualitative aspects of physical activity and sleep quality as significant factors influencing the current and future psychosocial health of children, even at a very early age (< 3 years).