bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis Kegagalan Material Aluminium 5052 sebagai Aplikasi Bahan Lambung Kapal Terhadap Pengaruh Salinitas Air Laut
Authors: Kusminah Imah Luluk , Wardani Dianita , Pramesty Lely , Indarto Richo Oktavian 
Published: January 2023

Sebagai negara kepulauan, maka untuk menghubungkan antar pulau di Indonesia peranan transportasi kapal laut sangat penting. Dalam perencanaan konstruksi kapal, material lambung kapal menjadi faktor penting karena sering terjadi korosi. Korosi adalah kerusakan material akibat adanya reaksi kimia. Penelitian ini menggunakan metode eksperimen. Secara kuantitatif material aluminium dihitung kehilangan berat sesuai dengan ASTM G31-72, kemudian melakukan perhitungan laju korosi dan menganalisa faktor yang mempengaruhi laju korosi dengan pengujian XRD. Dari hasil pengujian weight loss, laju korosi terbesar terjadi pada material yang terletak pada kondisi salinitas 3,6% NaCl sebesar 12,18 mpy dengan waktu perendaman selama 1 bulan. Konsentrasi larutan NaCl yang lebih tinggi menghasilkan lebih banyak ion klorida di sekitar logam, menyebabkan desensitisasi permukaan logam. Dari hasil analisa XRD menunjukkan terdapat senyawa 2NaAlO2 dan Al2O3 pada intensitas peak tertinggi. Data tersebut menunjukkan terbentuknya senyawa yang melekat dengan permukaan aluminium yang terekspos dalam larutan klorida, yang berfungsi melindungi logam dari korosi.
Peramalan Harga Crude Oil dengan Model Double Exponensial Smoothing-Holts
Authors: As’ad Mohamad , Yuniar Eka , Sujito  , Farida Eni , Setyowibowo Sigit 
Published: January 2023

Kenaikan harga bahan bakar minyak (BBM) oleh pemerintah sangat ramai sekali di respon masyarakat. Crude oil merupakan bahan baku BBM. Harga crude oil tergantung pasar dunia. Penelitian ini bertujuan untuk meramalkan harga crude oil bulanan secara cepat dan akurat dengan menggunakan model yang mudah dan dengan software yang mudah didapat. Penelitian ini memakai model double exponensial smoothing dari Holts (DES-H). Data sekunder diperoleh dari “Spot Crude Oil Price: West Texas Intermediate (WTISPLC)”. Hasil penelitian ini dengan model DES-H mendapatkan parameter alpha sebesar 0,9999 dan parameter beta sebesar 1e-04. Nilai akurasi peramalan yaitu RMSE sebesar 5.813075 dan MAPE sebesar 7.451311 % (sangat bagus). Penambahan data terbaru sangat penting untuk update model dan digunakan untuk peramalan jangka pendek.
Pengaruh Jumlah Sudu Turbin Air Crossflow Terhadap Kinerja Pembangkit Mini Hidro
Authors: Budiarsyah Ginanjar , Putra Mohammad Alexin 
Published: January 2023

Unjuk kerja suatu turbin air dapat dinilai dari daya dan torsi turbin yang dihasilkan. penelitian bertujuan untuk mengetahui pengaruh jumlah sudu terhadap kinerja turbin mini hidro dengan variasi debit. Pada penelitian turbin air crossflow, pengujian dilakukan pada aliran bawah. Penelitian ini menggunakan variasi debit 0.49 l/s dan 0.53 l/s. Dengan variasi jumlah sudu 15 dan 30, hasil pengujian menunjukan bahwa torsi yang didapat berbanding lurus dengan meningkatnya debit, rpm dan jumlah sudu sehingga mempengaruhi nilai torsi dan daya turbin yang dihasilkan. Pada kondisi debit 0,49 l/s daya terbesar untuk sudu 30 terdapat pada putaran 89,3 rpm dengan daya turbin 0.0037 daya terendah pada putaran 32 rpm yakni 0.0018 dengan jumlah sudu 15. Sedangkan pada kondisi 0.53 l/s Daya terbesar terdapat pada putaran 98.4 rpm dengan daya sebesar 0,0051 jumlah sudu 30 dan daya terendah putaran 40.4 rpm dengan daya 0,0025 debit 0.53 l/s jumlah sudu 15.
Uso de herramientas tecnológicas en educación: Estudio de revisión.
Authors: Marín-Campos Elmer 
Published: January 2023

La presente investigación tiene como objetivo identificar y recopilar artículos científicos en relación con el uso de herramientas tecnológicas (HT) en educación en los últimos 3 años, producto de la Covid-19, consultándose base de datos de Scopus, Redalyc y Scielo; para tal efecto, se utilizó como metodología el enfoque cuantitativo, con diseño descriptivo, empleando como instrumento la ficha de registro de artículos, además las técnicas de revisión sistemática, análisis documental, lectura crítica y parafraseo. La población estuvo constituida por 90 artículos científicos originales de experiencia pedagógica y teórica. Teniendo una muestra final de 40 artículos relacionada con el uso de herramientas tecnológicas. Se obtuvo los siguientes resultados, al utilizar HT en el proceso de enseñanza - aprendizaje permite la interacción entre docente y estudiante de manera colaborativa, dinámica e innovadora, fortaleciendo sus competencias digitales en docentes a la vez del estudiantado. Además, permite adaptarse a las nuevas formas de enseñar y aprender usando la tecnología como forma de actualización pedagógica, desprendiéndose de la práctica tradicional. Se concluye que, según fuentes revisadas se vine aplicando un conjunto de herramientas tecnológicas en la enseñanza - aprendizaje en los diferentes niveles educativos. Por ello, se sugiere seguir capacitando a los maestros y maestras con el fin de continuar fortaleciendo sus competencias digitales, pedagógicas; para enseñar y aprender acorde al contexto. Siendo el docente innovador, el estudiante protagonista y la tecnología mediadora de los aprendizajes y al mismo tiempo reducir la brecha digital.
Cuidados com a voz do professor: análise de uma ação oferecida em modalidade semi-presencial
Authors: Ferreira Raiza Mendes , Ferreira Léslie Piccolotto , Souza Thelma Mello Thomé de , Giannini Susana Pimentel Pinto , Rangel Ana Carolina Fonseca 
Published: January 2023

Objetivo: analisar o conhecimento sobre práticas de autocuidado com a voz adquirido por professores comparando dois períodos. Método: pesquisa transversal, realizada com 129 professores que realizaram um curso oferecido na modalidade semipresencial e responderam um questionário para avaliar o conhecimento adquirido. Os participantes foram divididos em dois grupos: G1 (n=74), que respondeu seis meses após a conclusão do curso, e G2 (n=55), um ano. Os dados coletados foram submetidos a testes estatísticos. Resultados: a comparação entre as duas turmas evidenciou que a categoria “prática de autocuidado com a voz no dia a dia profissional” registrou diferença (p=0,031), em que G1 foi maior (100,0%) do que G2 (92,7%). Também houve diferença (p=0,004) quanto ao aspecto “pensa em usar estratégias para melhorar o ambiente de trabalho” (G1=75,7% e G2=94,5%). Conclusão: os aspectos mais mencionados foram preocupação com hidratação, realizar exercícios vocais e não forçar a voz/não gritar. Houve pouca diferença entre os grupos.
HABITUS MENONTON SINETRON PARA IBU RUMAH TANGGA DI KELURAHAN TLOGOANYAR KABUPATEN LAMONGAN
Authors: Anggraini Kiky Chandra Silvia 
Published: January 2023

Kegiatan menonton sinteron merupakan kegiatan favorit para ibu rumah tangga. proses terbentuknya menonton sinetron memerlukan proses berpikir dan interpretasi pengalaman. oleh sebab itu penelitian ini bertujuan untuk mengetahui bagaimana habitus menonton sinetron para ibu rumah tangga di RT -3 RW 02. Penelitian merupakan penelitian kualitatif deskripsi dengan teknik pengumpulan data berupa wawancara dan observasi yang kemudian akan dianalisis dengan teori Miles dan Huberman. Hasil penelitian ini diperoleh data terdapat tiga macam kategori yaitu habitus mandiri, habitus sugesti dan habistus adaptasi
The cryoEM structure of cytochrome bd from C. glutamicum provides novel insights into structural properties of actinobacterial terminal oxidases
Authors: Grund Tamara N. , Kabashima Yoshiki , Kusumoto Tomoichirou , Wu Di , Welsch Sonja , Sakamoto Junshi , Michel Hartmut , Safarian Schara 
Published: January 2023

Cytochromes bd are essential for microaerobic respiration of many prokaryotes including a number of human pathogens. These enzymes catalyze the reduction of molecular oxygen to water using quinols as electron donors. Their importance for prokaryotic survival and the absence of eukaryotic homologs make these enzyme ideal targets for antimicrobial drugs. Here, we determined the cryoEM structure of the menaquinol-oxidizing cytochrome bd-type oxygen reductase of the facultative anaerobic Actinobacterium Corynebacterium glutamicum at a resolution of 2.7 Å. The obtained structure adopts the signature pseudosymmetrical heterodimeric architecture of canonical cytochrome bd oxidases formed by the core subunits CydA and CydB. No accessory subunits were identified for this cytochrome bd homolog. The two b-type hemes and the oxygen binding heme d are organized in a triangular geometry with a protein environment around these redox cofactors similar to that of the closely related cytochrome bd from M. tuberculosis. We identified oxygen and a proton conducting channels emerging from the membrane space and the cytoplasm, respectively. Compared to the prototypical enzyme homolog from the E. coli, the most apparent difference is found in the location and size of the proton channel entry site. In canonical cytochrome bd oxidases quinol oxidation occurs at the highly flexible periplasmic Q-loop located in the loop region between TMHs six and seven. An alternative quinol-binding site near heme b595 was previously identified for cytochrome bd from M. tuberculosis. We discuss the relevance of the two quinol oxidation sites in actinobacterial bd-type oxidases and highlight important differences that may explain functional and electrochemical differences between C. glutamicum and M. tuberculosis. This study expands our current understanding of the structural diversity of actinobacterial and proteobacterial cytochrome bd oxygen reductases and provides deeper insights into the unique structural and functional properties of various cytochrome bd variants from different phylae.
Effects of Zhishi Daozhi Decoction on the intestinal flora of nonalcoholic fatty liver disease mice induced by a high-fat diet
Authors: Bi Chao-Ran , Sun Jia-Tong , Du Jian , Chu Li-Yuan , Li Yi-Jing , Jia Xiao-Yu , Liu Yuan , Zhang Wen-Ping , Li Yu-Chun , Liu Yan-Jing 
Published: January 2023

Background and aimsNonalcoholic fatty liver disease (NAFLD) is the most common type of chronic liver disease with a high incidence, and the situation is not optimistic. Intestinal flora imbalance is strongly correlated with NAFLD pathogenesis. Zhishi Daozhi Decoction (ZDD) is a water decoction of the herbs used in the classical Chinese medicine prescription Zhishi Daozhi Pills. Zhishi Daozhi Pills has shown promising hepatoprotective and hypolipidemic properties, but its specific mechanism remains unclear.MethodsMice were fed on a high fat-rich diet (HFD) for ten weeks, and then the animals were administrated ZDD through oral gavage for four weeks. The serum liver function and blood lipid indexes of the mice were then tested using an automatic biochemical analyzer. H&amp;E and Oil Red O staining were used to observe the pathological conditions of mice liver tissue, and 16S rRNA sequencing technology was used to analyze the changes in intestinal flora of mice. The concentration of short-chain fatty acids (SCFAs) in the gut of mice was analyzed by gas chromatography-mass spectrometry (GC-MS). The expression of tight junction (TJ) proteins between ileal mucosal epithelial cells was analyzed using the immunofluorescence technique.ResultsZDD was found to reduce the bodyweight of NAFLD mice, reduce serum TG, CHO, ALT, and AST levels, reduce fat accumulation in liver tissue, make the structure of intestinal flora comparable to the control group, and increase the concentration of intestinal SCFAs. It was also found to increase the expression of TJ proteins such as occludin and ZO-1, making them comparable to the control group.ConclusionsZDD has a therapeutic effect on NAFLD mice induced by HFD, which may act by optimizing the intestinal flora structure.
A Novel Approach to Left Ventricular Filling Pressure Assessment: The Role of Hemodynamic Forces Analysis
Authors: Airale Lorenzo , Vallelonga Fabrizio , Forni Tommaso , Leone Dario , Magnino Corrado , Avenatti Eleonora , Iannaccone Andrea , Astarita Anna , Mingrone Giulia , Cesareo Marco , Giordana Carlo , Omedè Pierluigi , Moretti Claudio , Veglio Franco , Pedrizzetti Gianni , Milan Alberto 
Published: January 2023

Graphical AbstractRisk variation of presenting increased left ventricular filling pressure (upper graph) and PCWP variation (lower graph), according to the proposed scoring system. EF, ejection fraction; DLF, diastolic longitudinal force; LAe, left atrial enlargement; ILFP, increased left ventricular filling pressure; NLFP, normal left ventricular filling pressure; PCWP, postcapillary wedge pressure.
Jia-Wei-Si-Miao-Yong-An decoction modulates intestinal flora and metabolites in acute coronary syndrome model
Authors: Zhao Ning , Wang Ying , Ma Yan , Liang Xiaoxue , Zhang Xi , Gao Yuan , Dong Yingying , Bai Dong , Hu Jingqing 
Published: January 2023

AimsWe assessed the efficacy of the traditional Chinese medicine formulation Jia-Wei-Si-Miao-Yong-An decoction (HJ11) in the treatment of acute coronary syndrome and evaluated its impact on the intestinal microbiota and their metabolites.MethodsAn acute coronary syndrome model was established in rats, which were randomly assigned to the model, HJ11 treatment, and atorvastatin treatment groups. Rats were then administered saline solution (model and sham operation control groups) or drugs by oral gavage for 28 d. Echocardiography was performed and serum creatine kinase-MB and cardiac troponin I levels were monitored to examine the cardiac function. Inflammation was evaluated using hematoxylin and eosin staining of heart tissue, and serum interleukin-2, interleukin-6, tumor necrosis factor alpha, and high-sensitivity C-reactive protein measurements. Gut microbiota composition was analyzed via 16S rRNA gene sequencing. Metabolomics was used to determine fecal metabolites and elucidate the modes of action of HJ11 in acute coronary syndrome treatment.ResultsHJ11 improved cardiac function and attenuated inflammation in rats with acute coronary syndrome. Relative to the untreated model group, the HJ11-treated group presented normalized Firmicutes/Bacteroidetes ratio and reduced abundances of the bacterial genera norank_f__Ruminococcaceae, Desulfovibrio, Clostridium_sensu_stricto_1, Adlercreutzia, Staphylococcus, Bacteroides, Prevotella, Rikenellaceae_RC9_gut_group, unclassified_o__Bacteroidales, and Ruminococcus_gauvreauii_group. We found 23 differentially expressed intestinal metabolites, and the enriched metabolic pathways were mainly related to amino acid metabolism. We also discovered that asymmetric dimethylarginine levels were strongly associated with cardiovascular disease. Correlation analyses revealed strong associations among intestinal microflora, their metabolites, proinflammatory factors, and cardiac function. Hence, the therapeutic effects of HJ11 on acute coronary syndrome are related to specific alterations in gut microbiota and their metabolites.ConclusionThis work demonstrated that HJ11 effectively treats acute coronary syndrome. HJ11 seems to increase the abundance of beneficial bacterial taxa (Bacteroides and Rikenellaceae_RC9_gut_group), mitigate the risk factors associated with cardiovascular disease, alter bacterial metabolites, lower asymmetric dimethylarginine levels, and effectively treat acute coronary syndrome.
Traditional Baduanjin exercise through the eyes of patients with chronic heart failure: A qualitative content analysis study
Authors: Chen Xiankun , Jiang Wei , Salazar Mariano , Zhu Huiying , Wen Zehuai , Chen Xixi , Lundborg Cecilia Stålsby 
Published: January 2023

ObjectiveBaduanjin (eight silken movements) is a traditional Chinese exercise that can be used as cardiac rehabilitation therapy for patients with chronic heart failure (CHF) especially when other forms of rehabilitation are scarce or unaffordable. This study explores the experiences of Chinese patients with CHF who undertook Baduanjin exercise at home as part of a pilot trial in Guangzhou, China.MethodsWe conducted seven qualitative interviews with participants who had participated in the intervention arm of a pilot randomized controlled trial (RCT) (n = 8). For data collection, we used a semi-structured interview guide with both open-ended, and follow-up questions. We audio recorded the interviews, transcribed them verbatim, and then analyzed them with content analysis.ResultsParticipants’ experiences of doing Baduanjin were classified into three categories: (1) improving practice (2) factors facilitating good exercise adherence, and (3) feeling good. Participants reported that the exercises were easy but that the correct Baduanjin execution and coordination between the mind, movements, and breathing were only achievable through practice. In addition, the training benefits which they perceived were the predominant motivation for patients to keep practicing. Finally, trust in Baduanjin, personal attitudes toward health, flexibility in practice times, as well as social support helped the participants to achieve good adherence to home-based training.ConclusionThis study’s findings indicate that Baduanjin could be a cardiac rehabilitation exercise modality for patients with CHF in China, especially in a home-based setting.
Charcoal in Kunlun Mountains loess: Implications for environment change and human activity during the middle Holocene
Authors: Pan Yanfang , Mu Guijin , Gao Cunhai , Behling Herman , Liu Dexin , Wu Guangyang 
Published: January 2023

Loess sediment charcoal records are used in paleoecological analyses to reconstruct fire history and human activities. The Tarim Basin is bordered to the south by the Kunlun Mountains, where eolian silt or loess is extensive and has continued to be deposited in modern times. In this study, we conducted multiple analyses of a 720 cm–thick loess section (KLA) at 3,516 m elevation in the Kunlun Mountains to reconstruct the middle Holocene vegetation history in northern China. Our palynological, charcoal, and grain-size data reveal a slightly drying trend with notable moisture fluctuations in the Kunlun highland since ∼4.9 kyr (1 kyr = 1,000 cal yr BP). At approximately 4.1, 2.0, and 1.0 kyr, the climate became more arid; the intervals of 4.0–3.2, 2.4–1.9 and 0.7–0.5 kyr were relatively wet periods. Some sand activity phases in the southern margin of the Taklimakan Desert are recorded around 4.0–3.5, 2.5–2.3, and 1.2–0.7 kyr. Stronger human activities commenced at approximately 2.0 kyr. On the basis of sedimentary charcoal concentrations and regional paleoclimatic and archaeological records, we propose that micro charcoal (&lt;50 μm) originated from the Tarim Basin, reflecting human activity in the basin. Macro charcoal (&gt;50 μm) is suitable for reconstructing Kunlun highland fire events. We suggest that increased anthropogenic activities such as agriculture, construction, and wars played an important role in land degradation and abandonment of ancient cities in the southern Tarim Basin. Our results provide new insights into the role of humans in the ecological evolution of inland arid areas in China during the middle Holocene.
Do pupils at research-informed schools actually perform better? Findings from a study at English schools
Authors: Groß Ophoff Jana , Brown Chris , Helm Christoph 
Published: January 2023

IntroductionAcross the globe, many national, state, and district level governments are increasingly seeking to bring about school “self improvement” via the fostering of change, which, at best, is based on or informed by research, evidence, and data. According to the conceptualization of research-informed education as inquiry cycle, it is reasoned that there is value in combining the approaches of data-based decision-making and evidence-informed education. The originality of this paper lies in challenging common claims that teachers’ engagement with research supports development processes at schools and pupil performance.MethodsTo put this assumption to test, a data-set based on 1,457 staff members from 73 English primary schools (school year 2014/2015) was (re-)analyzed in this paper. Not only survey information about trust among colleagues, organizational learning and the research use climate was used (cf. Brown et al., 2016), but also the results from the most recent school inspections and the results from standardized assessment at the end of primary school. Of particular interest was, as to whether the perceived research use climate mediates the association between organizational learning and trust at school on the one hand and the average pupil performance on the other, and whether schools that were rated as “outstanding,” “good,” or “requires improvement” in their most recent school inspection differ in that regard. Data was analyzed based on multi-level structural equation modelling.ResultsOur findings indicate that schools with a higher average value of trust among colleagues report more organizational and research informed activities, but also demonstrate better results in the average pupil performance assessment at the end of the school year. This was particularly true for schools rated as “good” in previous school inspections. In contrast, both “outstanding” schools and schools that “require improvement” appeared to engage more with research evidence, even though the former seemed not to profit from it.DiscussionThe conclusion is drawn that a comprehensive model of research-informed education can contribute to more conceptual clarity in future research, and based on that, to theoretical development.
A network pharmacology study on mechanism of resveratrol in treating preeclampsia via regulation of AGE-RAGE and HIF-1 signalling pathways
Authors: Shi Jiamiao , Wang Jiahao , Jia Ning , Sun Qinru 
Published: January 2023

BackgroundPreeclampsia (PE) is a hypertensive disorder of pregnancy that threatens the lives of millions of pregnant women and their babies worldwide. Without effective medications, there are thousands of maternal and child mortalities every year. Resveratrol (RSV), a non-flavonoid polyphenol extracted from multiple plants, has shown positive effects in treating hypertension, cardiovascular disorders, and even PE. This study aimed to explore the pharmacological mechanism of RSV in treating PE by using network pharmacology and bioinformatics.MethodsWith the use of multiple databases, 66 intersecting targets were obtained from the 347 putative targets of RSV and 526 PE-related genes. Then, Gene Ontology (GO) analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis were conducted to investigate the functions of the intersecting targets. The protein–protein interaction network and target–pathway network were drawn and analyzed to illustrate the correlation between targets and pathways. Finally, molecular docking was conducted to calculate the binding energy between RSV and core targets.ResultsThe results showed that the core targets of RSV were IL6, TNF, IL1B, VEGFA, STAT3, and EGFR. There existed good binding between RSV and IL6, TNF, IL1B, VEGFA, and EGFR. In addition, we found that RSV mainly functioned in the AGE-RAGE and HIF-1 signaling pathways, which are associated with the occurrence and development of PE.ConclusionIn conclusion, our findings indicated that RSV has the effects of regulating angiogenesis and anti-inflammation and can be a candidate medicine for treating PE.