bluuebunny/crossref_metadata_2025_split huggingface dataset:
“Infinite Subdued Vexation”: Love, Agency, and Frustration in Melville’s Pierre; or the Ambiguities
Authors: Jonik Michael 
Published: May 2023

Le roman de Herman Melville, Pierre; ou les Ambiguïtés (1852), n’est certes en aucun cas le seul roman du xixe siècle à lier les mystères de l’action aux mystères de l’amour. Toutefois il propose une exploration unique en son genre de la façon dont les causalités complexes de l’action et de l’inaction se mêlent aux économies libidinales de satisfaction et de frustration de l’amour. Et comme il sied à un roman psycho-philosophique marqué d’ambiguïtés affectives, la frustration, loin d’être le revers de la satisfaction, se confond avec elle. Pierre incarne alors l’une des « paraboles de la volonté » que constituent chez Melville d’autres figures comme Moby-Dick ou Bartleby, le Scribe. Mais peut-être offre-t‑il aussi la vision melvillienne la plus large sur la façon dont des indices mystérieux, des intuitions irrésistibles ou des agents externes peuvent façonner nos vies affectives.
L’appropriation collective du foncier au service d’une agriculture ancrée dans son environnement naturel
Authors: Crézé Ronan 
Published: May 2023

Depuis 35 ans, la SCTL expérimente la gestion collective de 6 300 hectares de terres publiques. La gouvernance de cet organisme foncier est assurée par les habitants (agricoles et non agricoles) qui se donnent encore aujourd’hui comme objectif de maintenir et préserver l’usage agricole du territoire. Cette modalité de gestion du foncier participe au développement de pratiques agricoles respectueuses de l’environnement dans un milieu écologiquement sensible où la nature sauvage occupe une place importante.
Autour de la propriété ? La « communalisation » des ressources en eau grenobloises aux prises avec la rationalisation administrative territoriale
Authors: Renou Yvan , Brochet Antoine 
Published: May 2023

Cet article vise à mieux comprendre comment se forment historiquement des trajectoires d’aménagement hydrosocial de territoires singuliers et à mieux cerner la fragilité de leur consolidation dans le temps. Informés par les travaux récents de l’approche du « commoning », on montre que la « communalisation des ressources en eau » qui a pu être portée historiquement par des associations syndicales sur le territoire grenoblois s’est trouvée fragilisée, voire partiellement remise en cause dans sa légitimité, par l’affirmation d’une logique d’action publique infusée de rationalité administrative. L’analyse attentive des « jeux du commoning » qui se déploient actuellement sur ce territoire laisse toutefois apparaître des stratégies de résistance inédites face à la domination croissante des règles et des droits formels.
Female Representation in Pediatric Ophthalmology at the American Academy of Ophthalmology Annual Meeting From 2018 to 2022
Authors: Hucko Lauren , Pajek Sarah , Robles-Holmes Hailey , Watane Arjun , Sridhar Jayanth , Cavuoto Kara M. 
Published: May 2023

Purpose:
To identify trends in female pediatric ophthalmologist authorship and representation at the American Academy of Ophthalmology (AAO) Annual Meeting from 2018 to 2022.

Methods:
Participant data from 2018 to 2022 were collected from the AAO website, organized by conference activity (papers, posters, instruction courses, videos, symposia, subspecialty day, and awards), and analyzed by sex using an online tool. Chi-squared and odds ratio analyses were performed to determine trends in authorship sex and associations between the sex of paper and poster authors in each category.

Results:

Of 923 pediatric ophthalmology presentations from 2018 to 2022, 46.2% (426 of 923) of presenters and 46.6% (281 of 603) of unique individual participants were women. Overall, 48% (174 of 362) of first and senior authors of papers and posters were women. No significant difference or association between female first and senior authors was observed (52% vs 44%,
P
= .14; odds ratio 1.59,
P
= .13). There was no significant change in the proportion of total female presenters from 2018 to 2019 (−3.09%,
P
= .53), 2019 to 2020 (0.76%,
P
= .88), 2020 to 2021 (9.09%,
P
= .09), 2021 to 2022 (−5.68%,
P
= .30), or 2018 to 2022 (1.08%,
P
= .84).

Conclusions:
Since 2018, female representation at the AAO Annual Meeting has remained consistent and nears 50%. The lack of a significant difference between the proportion of female first and senior authors suggests that junior female pediatric ophthalmologists are climbing the ranks and more broadly engaging in mentorship roles. Considering the increasing proportion of female pediatric ophthalmologists, the absence of corollary, statistically significant increases in female participation may be of concern.

[
J Pediatr Ophthalmol Strabismus
. 2024;61(1):6–13.]
3-MCPD and glycidol levels in edible oils and fats obtained from local markets in Türkiye
Authors: Gündüz A.O. , Ceylan M.M. , Baştürk A. 
Published: May 2023

In this study, it was aimed to determine the 3-MCPD and glycidol levels in 9 types (46 brands) of edible fat and oil offered for sale in markets located in Türkiye. 3-MCPD and glycidol levels were determined by making some modifications to the DGF C VI 18 (10) method. The highest levels of 3-MCPD and glycidol levels were detected in hazelnut oils, riviera olive oils, margarines, and shortenings. As expected, these contaminants were not observed in extra-virgin olive oils, while they were detected at low levels in fish oils. The highest 3-MCPD levels were found in the range of 0.06-2.12 mg·kg-1 in hazelnut oil, 0.16-1.69 mg·kg-1 in riviera olive oils, and 0.17-1.17 mg·kg-1 in margarines. The highest glycidol levels were found in the shortenings in the range of 1.98-6.46 mg·kg-1, followed by hazelnut oil (0.54-2.63 mg·kg-1) and riviera olive oil (0.19-3.53 mg·kg-1).
Fatty acids and mineral composition of seed oils extracted from different Rosa L. taxa
Authors: Hatipoglu I.H. , Ak B.E. 
Published: May 2023

In the study, the macro and micro elements and fatty acid contents in rose seeds, which are generally evaluated in the waste category, were determined. Among the plants belonging to these taxa, only the registered varieties belonging to four taxa were used, while the others were genotypes. The plant materials of the study include rosehip (R. canina L.), Yildiz variety of rosehip (R. canina L. cv ‘Yildiz’), Syrup rose (R. heckeliana Tratt. subsp. vanheurckiana), Austrian briar (R. foetida Herrm.), lax rootstock [R. caesia Sm. (Syn: R. laxa Retz.)], wild rose [R. montana subsp. woronovii Chaix subsp. woronovii (Lonacz) Ö. Nilsson L.], hybrid landscape roses (R. x hybrida) and Hosap rose [R. pisiformis (Christ) D.] taxa. It was determined that the contents of nitrogen, potassium, phosphorus, magnesium and calcium of the macro elements examined in the seed samples differed statistically from each other. The seeds of different Rosa L. species examined within the scope of the research can be considered as one of the fruit oil sources with its 3.71-10.01% oil content. The fatty acid contents were determined as follows: linoleic acid (ω6) contents in the taxa ranged from 41.63 to 50.11% with an average of 44.88%; oleic acid (ω9) ranged from 20.80 to 30.27% with an average of 24.95%; linolenic acid (ω3) varied between 14.00-28.51% with an average of 19.20%; arachidic acid ranged from 0.75-1.63% and the average was 1.97%; eicosenoic acid ranged between 0.13-0.65% and averaged 0.33%; palmitoleic acid contents ranged from 0.08-0.60; behenic acid varied between 0.08-0.19% with 0.11% average. It was observed that the (ω3/ω6 ratio of the hybrid rose, which is especially used as a landscape rose and whose fruits are not evaluated, had an average value. R. canina ‘Yildiz’ cultivar showed a high (ω3/ω6 ratio, which is important in health terms. The high oleic acid contents found in these taxa are important results.
Le contrôle du juge sur le motif économique de licenciement – Comparaison franco-allemande
Authors: Dabosville Benjamin 
Published: May 2023

L’analyse de décisions de justice montre que, en matière de licenciement pour motif économique, une logique différente est à l’œuvre de part et d’autre du Rhin : alors que le juge français contrôle étroitement les raisons économiques à l’origine de la décision, c’est sur les conséquences organisationnelles que se porte essentiellement le contrôle du juge allemand.
Le juge et les pouvoirs de gestion de l’employeur en Turquie
Authors: Sur Melda 
Published: May 2023

Le juge, s’appuyant sur des dispositions du Code du travail, use largement de son pouvoir d’appréciation en vue de protéger les travailleurs. Ainsi, les salariés d’un sous-traitant ont la possibilité d’obtenir en justice la création d’un lien contractuel avec l’employeur bénéficiaire, et les contrats à durée déterminée peuvent être requalifiés en contrats à durée indéterminée. Dans le cadre de la protection contre les licenciements, des principes établis par la jurisprudence servent de base au contrôle du juge : le licenciement, ne sera qu’un dernier recours, proportionné et en cohérence avec les autres choix de gestion. L’employeur est tenu de justifier et de documenter les raisons de la réduction d’effectifs et du choix de ceux qui seront licenciés. Au final, les principes de traitement égal (article 5 du Code du travail) et de bonne foi (article 2 du Code Civil), couplés à un souci de sauvegarde de l’emploi, constituent les principaux fondements de l’ingérence et du pouvoir d’appréciation du juge, qui s’étendent ainsi au-delà des limites posées par la loi.
Les droits collectifs du travail et la question du genre dans les systèmes interaméricain et européen des droits de l’homme
Authors: Gorrochategui Polo María 
Published: May 2023

L’avis consultatif OC 27/21 émis par la Cour interaméricaine des droits de l’homme fournit une interprétation de la portée générale des obligations des États dans le cadre du système interaméricain sur les droits à la liberté d’association, à la négociation collective et à la grève, dans une perspective de genre. Cet article analyse la portée et l’impact de l’OC 27/21 sur deux aspects spécifiques particulièrement intéressants et pertinents : le droit de grève et sa reconnaissance en tant que droit fondamental par la Cour interaméricaine des droits de l’homme d’une part, et d’autre part, l’exercice des droits collectifs du travail dans une perspective de genre.
Effect of mangosteen skin ethanol extract on streptozotocin-induced TNF-α expression
Authors: Herdiani Novera , Wirjatmadi Bambang , Kuntoro Kuntoro , Zamzam Maki 
Published: May 2023

Introduction: Diabetes Mellitus (DM) is a significant health problem worldwide. DM with poor control of blood glucose levels can eventually cause pancreatic cell disorders, including a decrease in cell mass and function. Mangosteen rind contains xanthone compounds that can be used to protect and reduce cell damage, especially those caused by free radicals. This study aimed to analyze the administration of mangosteen peel ethanol extract on the expression of TNF-α induced by streptozotocin.Materials and Methods: The research was carried out in an experimental laboratory. The research design used was Randomized Post Test Only Control Group Design. The sample is a male rat Wistar strain. Rats were grouped into five groups, namely negative control group, positive control STZ, mangosteen peel extract at a dose of 200 mg/kg BW (K2), a dose of 400 mg/kg BW (K3), an amount of 600 mg/kg BW (K4). Administration of therapy for 14 days orally.Results: The effects of the mangosteen rind extract had a lower TNF- positive cell count of 3.83 compared to the group that was not treated with the mangosteen rind extract 19.33. All treatment groups showed a significant difference (P0.001) in the number of TNF- protein-expressing cells. This research can inform the public that mangosteen peel’s benefits can be developed as prevention and alternative treatment in humans caused by inflammation.Conclusions: This research affects the administration of ethanol extract of mangosteen peel to decrease the number of TNFpositive cells with an effective dose of 600 mg/kg BW.
Connecting neurodevelopment to neurodegeneration: a spotlight on the role of kinesin superfamily protein 2A (KIF2A)
Authors: Ruiz-Reig Nuria , Hakanen Janne , Tissir Fadel 
Published: May 2023

Abstract
Microtubules play a central role in cytoskeletal changes during neuronal development and maintenance. Microtubule dynamics is essential to polarity and shape transitions underlying neural cell division, differentiation, motility, and maturation. Kinesin superfamily protein 2A is a member of human kinesin 13 gene family of proteins that depolymerize and destabilize microtubules. In dividing cells, kinesin superfamily protein 2A is involved in mitotic progression, spindle assembly, and chromosome segregation. In postmitotic neurons, it is required for axon/dendrite specification and extension, neuronal migration, connectivity, and survival. Humans with kinesin superfamily protein 2A mutations suffer from a variety of malformations of cortical development, epilepsy, autism spectrum disorder, and neurodegeneration. In this review, we discuss how kinesin superfamily protein 2A regulates neuronal development and function, and how its deregulation causes neurodevelopmental and neurological disorders.
Adenosine A2A receptor blockade attenuates excitotoxicity in rat striatal medium spiny neurons during an ischemic-like insult
Authors: Coppi Elisabetta , Cherchi Federica , Gibb Alasdair J. 
Published: May 2023

Abstract
During brain ischemia, excitotoxicity and peri-infarct depolarization injuries occur and cause cerebral tissue damage. Indeed, anoxic depolarization, consisting of massive neuronal depolarization due to the loss of membrane ion gradients, occurs in vivo or in vitro during an energy failure. The neuromodulator adenosine is released in huge amounts during cerebral ischemia and exerts its effects by activating specific metabotropic receptors, namely: A1, A2A, A2B, and A3. The A2A receptor subtype is highly expressed in striatal medium spiny neurons, which are particularly susceptible to ischemic damage. Evidence indicates that the A2A receptors are upregulated in the rat striatum after stroke and the selective antagonist SCH58261 protects from exaggerated glutamate release within the first 4 hours from the insult and alleviates neurological impairment and histological injury in the following 24 hours. We recently added new knowledge to the mechanisms by which the adenosine A2A receptor subtype participates in ischemia-induced neuronal death by performing patch-clamp recordings from medium spiny neurons in rat striatal brain slices exposed to oxygen and glucose deprivation. We demonstrated that the selective block of A2A receptors by SCH58261 significantly reduced ionic imbalance and delayed the anoxic depolarization in medium spiny neurons during oxygen and glucose deprivation and that the mechanism involves voltage-gated K+ channel modulation and a presynaptic inhibition of glutamate release by the A2A receptor antagonist. The present review summarizes the latest findings in the literature about the possibility of developing selective ligands of A2A receptors as advantageous therapeutic tools that may contribute to counteracting neurodegeneration after brain ischemia.
Advances in extracellular vesicle-based combination therapies for spinal cord injury
Authors: Wang Tingting , Huang Guohao , Yi Zhiheng , Dai Sihan , Zhuang Weiduan , Guo Shaowei 
Published: May 2023

AbstractSpinal cord injury is a severe insult to the central nervous system that causes persisting neurological deficits. The currently available treatments involve surgical, medical, and rehabilitative strategies. However, none of these techniques can markedly reverse neurological deficits. Recently, extracellular vesicles from various cell sources have been applied to different models of spinal cord injury, thereby generating new cell-free therapies for the treatment of spinal cord injury. However, the use of extracellular vesicles alone is still associated with some notable shortcomings, such as their uncertainty in targeting damaged spinal cord tissues and inability to provide structural support to damaged axons. Therefore, this paper reviews the latest combined strategies for the use of extracellular vesicle-based technology for spinal cord injury, including the combination of extracellular vesicles with nanoparticles, exogenous drugs and/or biological scaffold materials, which facilitate the targeting ability of extracellular vesicles and the combinatorial effects with extracellular vesicles. We also highlight issues relating to the clinical transformation of these extracellular vesicle-based combination strategies for the treatment of spinal cord injury.
Role of lipids in the control of autophagy and primary cilium signaling in neurons
Authors: Hernández-Cáceres María Paz , Pinto-Nuñez Daniela , Rivera Patricia , Burgos Paulina , Díaz-Castro Francisco , Criollo Alfredo , Yañez Maria Jose , Morselli Eugenia 
Published: May 2023

AbstractThe brain is, after the adipose tissue, the organ with the greatest amount of lipids and diversity in their composition in the human body. In neurons, lipids are involved in signaling pathways controlling autophagy, a lysosome-dependent catabolic process essential for the maintenance of neuronal homeostasis and the function of the primary cilium, a cellular antenna that acts as a communication hub that transfers extracellular signals into intracellular responses required for neurogenesis and brain development. A crosstalk between primary cilia and autophagy has been established; however, its role in the control of neuronal activity and homeostasis is barely known. In this review, we briefly discuss the current knowledge regarding the role of autophagy and the primary cilium in neurons. Then we review the recent literature about specific lipid subclasses in the regulation of autophagy, in the control of primary cilium structure and its dependent cellular signaling in physiological and pathological conditions, specifically focusing on neurons, an area of research that could have major implications in neurodevelopment, energy homeostasis, and neurodegeneration.
Microshear bond strength of resin cement to a zirconia-reinforced lithium silicate glass ceramic using different surface treatments
Authors: Nakhaei Mohammadreza , Mohammadipour Hamideh-Sadat , Eslami Seyyed-Farzan , Soroush Zahra 
Published: May 2023

Background:
The purpose of this study was to evaluate the effect of different surface treatments on the microshear bond strength (μSBS) of resin cement to zirconia-reinforced lithium silicate ceramic and to compare it with lithium disilicate ceramic.

Materials and Methods:
In this in vitro study, 80 specimens containing two glass ceramics of IPS e.max press and VITA SUPRINITY were prepared and categorized into four groups according to the surface treatments (n = 10) as Group 1 (C): no treatment (control); Group 2 (HF): etching with 9% hydrofluoric acid (HF) for 90 s followed by silane application; Group 3 (SPH): sandblasting with Al2O3 particles (50 μm), etching with 35% phosphoric acid for 40 s followed by application of silane and adhesive (Clearfil liner bond F); and Group 4 (SB): sandblasting with Al2O3 followed by silanization. Then, a resin cement (Panavia F2) was applied to the prepared ceramic surfaces. All samples were subjected to thermal aging (5000 cycles, 5–55). The μSBS test was evaluated and failure modes were recorded. Data were analyzed using the Shapiro–Wilk, two-way analysis of variance and Tukey's Honest Significant Difference post hoc tests (P < 0.05).

Results:
IPS e.max press samples revealed significantly higher μSBS values compared to VITA SUPRINITY (P < 0.001), in whole surface treatments. The HF group showed the highest μSBS value, followed by the SPH and SB groups, respectively (P < 0.001). Adhesive failure was recorded as a predominant failure mode.

Conclusion:
The adhesion performance of IPS e.max press was significantly higher than VITA SUPRINITY. The common surface treatment protocol including HF application followed by silanization was the most effective surface treatment for both glass ceramics.
Analysis of mechanical properties of the stent's outflow segment during thoracic endovascular aortic repair
Authors: Shen Yu , Chen Zheng , Lu Qingsheng 
Published: May 2023

AIMS AND OBJECTIVES:
To discuss the mechanical properties of stents and optimize the stents' selection scheme of overlapping segment through in vitro mechanical simulation of stent grafts.

MATERIALS AND METHODS:
The radial force tester was used to measure the radial force of different aortic covered stents, bare stents and the combination of the two. Linear relationship between the radial force at the distal end of the stent and oversize rate was plotted. The stent-induced aortic wall shear stress was evaluated intuitively by mechanical simulation.

RESULTS:
The radial force curve of the distal end of the thoracic aortic covered stent reflected the superelastic characteristics of aortic stent, and the characteristics was more obvious in stents composed of nickel-titanium than stainless; When different size of Hercules stents were combined with the same sized restrictive bare stent, the oversize rate of overlapping segment was the same, and the radial force was similar; At the initial compression diameter, the use of restrictive bare stent can improve the chronic outward force, but at high compression level, the chronic outward force of the overlapping segment was higher than that of the individual aortic covered stent.

CONCLUSIONS:
Based on in vitro mechanical simulation, the stent-vessel wall interaction after implantation can be more intuitively understood. The application of restrictive bare stents can change the radial force of the overlapping segment of the stents by reducing the oversize rate of the distal end of the stent-graft, but it can be harmful at a higher compression level.
Preoperative Meal Practices
Authors: Shah Prerana Nirav , Kezo Azho 
Published: May 2023

Background:
In this era of enhanced recovery after surgery (ERAS), prolonged fasting has been discouraged. This study is an appraisal on the fasting practice in a tertiary hospital in India.

Materials and Methods:
Over a period of 1 year, 118 patients were taken into the study. The attending anesthesiologist noted the time of their last meal and the type of meal that was taken on the morning of surgery. Data were analyzed using STATA™ and Microsoft Excel version 2016.

Results:
Our study found that the fasting period for large and light meals was more and for clear fluids was 10.28 ± 3.63. For light meals and clear fluids, the fasting period was more than recommended.

Conclusion:
Prolonged preoperative fasting is still practiced despite existing guidelines. Prolonged preoperative fasting is still prevalent in today's era of ERAS. Education on the existing fasting guidelines and its implementation is needed.