bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recent substance use among clients with early psychosis and the potential to graduate from New Journeys
Authors: Fraser Elizabeth R. , Kordas Gordon , Stokes Bryony , McDonell Michael G. , Oluwoye Oladunni 
Published: January 2023

AbstractAimThis study examined the relationship between recent substance use prior to intake and program graduation among young adults with early psychosis enrolled in coordinated specialty care.MethodsParticipants (N = 248) were from New Journeys, a network of coordinated specialty care programs in Washington State. Recent (i.e., past 30 days) alcohol, cannabis, and other substance use was collected at intake and process data (e.g., contact) was collected by clinicians across a 2‐year period.ResultsAt intake, 32% of participants reported alcohol use only, 26% cannabis use only, and 15% both alcohol and cannabis use. Participants who reported alcohol use only (p = .02), cannabis use only (p = .03), and any substance use (p = .02) had significantly lower chances of graduating from coordinated specialty care than individuals who do not use substances.ConclusionsUnlike prior work, recent substance use influences clients' potential to graduate from New Journeys. Additional focus on the implementation of substance use treatment, with an emphasis on alcohol use, in coordinated specialty care programs is needed improve program completion rates.
The relevance of social anxiety for understanding social functioning and facial emotion recognition in individuals at clinical high‐risk for psychosis
Authors: Williams Trevor F. , Conley Rachel E. , Mittal Vijay A. 
Published: January 2023

AbstractAimIndividuals at clinical high risk (CHR) for psychosis often experience poor social functioning and impaired facial emotion recognition (FER); however, the impact of frequently comorbid symptoms upon these processes is underexplored. In particular, social anxiety is characteristic of this population and also related to poor social functioning and FER biases, such as misinterpreting neutral faces as negative or threatening; however, little is known about how social anxiety relates to these processes in CHR individuals. The present study examined the overlap of social anxiety, social functioning, and FER accuracy and bias.MethodParticipants (CHR N = 62, healthy controls N = 52) completed the self‐report Social Interaction Anxiety Scale (SIAS), Penn Emotion Recognition‐40 (ER‐40) behavioural task, and interviewer‐rated Global Functioning Scale‐Social (GFS‐S). The ER‐40 was used to assess both FER accuracy (e.g., overall number of correct responses) and bias (e.g., mislabelling neutral faces as angry).ResultsConsistent with previous research, relative to controls, CHR participants had more social anxiety (d = −1.07), poorer social functioning (d = −1.62), and performed more poorly on the FER task (e.g., d = −.37). Within CHR participants, social anxiety was related to an anger detection bias (r = .28), above and beyond positive symptom severity, which in turn was related to FER accuracy (r = .26) and social functioning (r = −.28).ConclusionThese findings suggest that ongoing work examining social processes within CHR individuals needs to account for social anxiety and that social anxiety may be a useful preventive intervention target.
Brief review of masseter muscle disorders
Authors: Aleman Monica 
Published: January 2023

SummaryRegional and systemic disorders of myopathic or neurogenic cause affecting the masticatory muscles have been reported or suspected in horses. The primary masticatory muscles include the masseter, temporalis, lateral and medial pterygoid muscles. The masseter muscle is the largest of the primary masticatory muscles and the most affected based on sporadic reports. This is a brief review of disorders involving the masseter muscle.
The prevalence of headshaking in horses with primary and secondary dental sinusitis and computed tomographic evidence of infraorbital canal pathology
Authors: Labbe Karyn A. , Allshouse Kimberly A. , Gilmour Lindsey J. , Arnold Carolyn E. , Whitfield‐Cargile Canaan M. , Griffin Cleet E. 
Published: January 2023

AbstractBackgroundSinusitis is a common disease of horses yet there are a limited number of reports in the literature that describe the prevalence of infraorbital canal (IOC) pathology and headshaking behaviour in horses diagnosed specifically with primary sinusitis and secondary dental sinusitis. Given the impact that these behaviours can have on horses' intended athletic use, investigation is warranted.ObjectivesTo determine the occurrence of IOC pathology in horses with concurrent primary or secondary dental sinusitis based on computed tomography (CT) findings and to assess whether the frequency of headshaking behaviour is influenced by the presence of IOC pathology.Study designRetrospective case series.MethodsComputed tomography studies were assessed for sinusitis (unilateral or bilateral), IOC pathology (unilateral or bilateral) and description of IOC disease including displacement, deformation, periosteal proliferation, hyperostosis, osteolysis and infraorbital nerve exposure. Behaviour outcome was determined by client questionnaire five or more years following CT scan.ResultsA total 65 out of 66 horses diagnosed with primary or secondary dental sinusitis demonstrated IOC changes on CT. Hyperostosis (86%), periosteal proliferation (85%) and osteolysis (86%) were common CT findings. Hyperostosis was frequently found to involve both the IOC and supporting bone structure. Five cases were euthanized immediately after CT acquisition or during hospitalisation following diagnostic investigations. Follow‐up was obtained in 48/61 cases, with five horses showing headshaking behaviour.Main limitationsInfraorbital nerve histopathology was not performed. The limited number of cases with no IOC pathology prevented direct comparison between sinusitis groups both with IOC pathology and without IOC changes. The client questionnaire carries a memory bias.ConclusionComputed tomography changes involving the IOC may not predict headshaking behaviours in sinusitis secondary to dental disease. This finding is important in the context that these behaviours render some horses unusable and unsafe for their intended riding discipline.
Association between insulin dysregulation and adrenocorticotropic hormone in aged horses and ponies with no clinical signs of pituitary pars intermedia dysfunction
Authors: Li Fang I. , Spence Robert J. , de Laat Melody A. , Harris Patricia A. , Sonntag Johanna , Menzies‐Gow Nicola J. , Durham Andy E. , Bailey Simon R. , Sillence Martin N. 
Published: January 2023

AbstractBackgroundHigh concentrations of adrenocorticotropic hormone (ACTH) are used as an indicator of pituitary pars intermedia dysfunction (PPID), but other factors that may influence ACTH need to be understood, if diagnostic reference ranges for ACTH are to be used with confidence. Insulin dysregulation (ID) could be one such factor, as insulin affects pituitary hormones in other species.ObjectivesTo test the hypothesis that a relationship exists between high insulin and high ACTH in aged (>15‐year‐old) animals with no clinical signs of PPID.Study designA cohort study.MethodsThirteen horses and eleven ponies (17–25 years‐old; mares and geldings) were clinically examined for signs of PPID in the spring (November 2020) and autumn (April 2021). On the same day, blood samples were taken before and 2 h after an oral glucose test (OGT). Concentrations of insulin, glucose, ACTH and cortisol were measured.ResultsThere was no association between ACTH and cortisol. However, there was a positive linear correlation between ACTH and post‐OGT (insulin in the autumn (r = 0.427, p = 0.04). Two horses and six ponies had ACTH above the cut‐off value for PPID diagnosis, and of these eight animals, six also had insulin concentrations above the cut‐off value for ID.Main limitationsThe cohort was small and thyrotropin‐releasing hormone (TRH) stimulation tests were not performed.ConclusionsIn autumn, high ACTH was associated with ID, when no clinical signs of PPID were present. Because ACTH is used in PPID diagnosis, further work is required to understand this interaction.
Impacts of motor phenotype on cognitive function in patients with Parkinson's disease 1 year after subthalamic‐nucleus deep brain stimulation
Authors: Wang Zhengyang , You ZhiFei 
Published: January 2023

BackgroundParkinson's disease (PD) is a neurological disorder that affects both motor and cognitive functioning. This study aimed to examine the impact of motor phenotype on cognitive function 1 year after subthalamic‐nucleus deep brain stimulation (STN‐DBS).MethodsThe prospectively collected data of 37 patients with PD were retrospectively analyzed. The patients were divided into two group according to their motor phenotype: the postural instability and gait disturbance (PIGD) group comprised 16 patients, and the tremor‐dominant (TD) group comprised 21 patients. The clinical characteristics and cognitive functions of all patients were examined at baseline and at the 1‐year follow‐up after STN‐DBS.ResultsThe data showed that STN‐DBS significantly improved motor functions (P < 0.05). A repeated‐measures analysis of variance indicated a considerable group × time interaction impact on the memory quotient score (P < 0.001) and Tmin (P = 0.033).ConclusionsA distinct relationship between the neuropsychological spectrum and motor phenotype of PD patients was observed at the 1‐year follow‐up after STN‐DBS, with worse cognitive outcomes in patients with the PIGD phenotype. Geriatr Gerontol Int 2023; 23: 85–90.
Conceptualising the ‘Administration of the Dead’: Cadavers, war and public health in the early 20th century
Authors: Fathi Romain 
Published: January 2023

AbstractThis article examines the relative absence of historical literature pertaining to the battlefield disposal of military corpses during and shortly after the First World War. It posits that while First World War Studies constitute an enormously rich field of research, scholars are yet to consider corpses and their disposal as a central topic of investigation, as is the case with other disciplines and historians of other conflicts. To address this lacuna, this article proposes the notion of ‘administration of the dead’ that may serve to both conceptualise and explore how First World War battlefield body disposal was performed. This article demonstrates the rich avenues that this topic opens to historians and sketches out areas of investigation such as the administrative, medical and technological dimensions of body disposal in the First World War.
Preparation and properties of anorthite‐based ceramics by using metallurgical solid waste and fly ash
Authors: Shen Can , Huang Yilun , Zhang Yuena , Wu Xiaowen , Tao Tianyi , Min Xin , Huang Zhaohui , Fang Minghao , Liu Yangai , Mi Ruiyu 
Published: January 2023

AbstractA large amount of metallurgical solid waste accumulation poses a serious threat to the environment. Study on synergistic reinforcement of synthetic process of metallurgical solid waste‐based ceramics with fly ash is of great significance in reducing environmental pollution and resource utilization. A metallurgical solid waste‐based ceramic used as building ceramic was developed with the erosion part of used MgO–C bricks and fly ash as main raw materials, and the amount of solid waste added to the prepared ceramics was at least 60 wt% and up to 90 wt%. The effects of fly ash content and sintering temperature on the crystalline phase transitions, morphologies, and the main physical and mechanical properties of ceramics were investigated by X‐ray diffraction, scanning electron microscopy, and mechanical testing. The results show that the obtained ceramics presented maximum bending strength and minimum water absorption, 80.14 MPa and 5.04%, respectively, when the raw material proportions were the erosion part of used refractories accounted for 60 wt%, fly ash 20 wt%, pyrophyllite 10 wt%, and quartz sands 10 wt%, and the process parameters were the sintering temperature 1150°C, sintering time 120 min, and molding pressure 15 MPa.
Synthesis and adsorption performance of fly ash/steel slag‐based geopolymer for removal of Cu (II) and methylene blue
Authors: Yan Shu , Feng Xue , Huang Kai , Ren Xiaoqi , Zhao Yang , Xing Pengfei 
Published: January 2023

AbstractIn order to realize the value‐added resource utilization of solid waste, geopolymer particle adsorbents were prepared at low temperatures using silica‐aluminum‐rich fly ash and steel slag powders as raw materials. In order to investigate the mechanism of their adsorption of dyes and heavy metal ions from wastewater, the effects of steel slag/fly ash ratio, adsorbent dosage, initial concentration of methylene blue (MB) and Cu2+ solution, adsorption time and temperature on the adsorption performance of the fly ash/steel slag‐based geopolymer adsorbents were investigated, systematically. Results presented that the adsorption capacities of MB and Cu2+ were 33.30 and 24.15 mg/g, and the removal efficiencies were 99.90% and 96.59% with the dosages of 3 and 4 g/L geopolymer adsorbents (steel slag/fly ash ratio of 20 wt.%), respectively. The adsorption processes of MB and Cu2+ on the adsorbents were in accordance with the proposed pseudo‐second‐order and Langmuir isotherm models, which mainly included physical and chemical adsorption mechanisms. The adsorption was a spontaneous endothermic process. The fly ash/steel slag‐based geopolymer had good removal ability for dyes and heavy metal ions, and it could maintain good adsorption performance after three cycles of regeneration. It had potential application in wastewater treatment.
Expansion microscopy: A revolution in diagnostic pathology
Authors: Ghosh Snehashish , Sapkota Bhawana Subedi , Rao Roopa S , Patil Shankargouda , Rajkumar Chandini , Lakshminarayan Surendra 
Published: January 2023

AbstractExpansion microscopy (ExM) is a recent discovery in diagnostic pathology and microbiology that promotes a physical magnification of the tissue specimen instead of optical magnification. It not only improves the resolution of the specimen but also enhances the diagnostic precision, and permits nanoscale imaging of the specimen. Optical microscopy is routinely used in histopathology and microbiology for ages. Due to its simplicity, compatibility with different types of specimens, and ease of operation it is accepted by pathologists. ExM and its variants have been widely tested in different types of tissue specimens and microbiological specimens and yielded brilliant results.
Effect of artificial aging on optical properties and crystalline structure of high‐translucency zirconia
Authors: Hajhamid Beshr , Bozec Laurent , Tenenbaum Howard , De Souza Grace , Somogyi‐Ganss Eszter 
Published: January 2023

AbstractPurposeTo investigate the effect of different in vitro aging protocols on the optical properties and crystalline structure of high‐translucency (HT) zirconia.Materials and methodsThirty‐six specimens of HT and extra‐high translucency (XT) zirconia were divided into three groups: control (CO)—no treatment; hydrothermal aging (HA)—autoclave aging for 12.5 h at 134°C, 2 bar; clinically related aging (CRA)—aging in the chewing simulator for 1.2 million cycles, followed by 50,000 thermocycles (5–55°C) and immersion in HCl (pH 1.2) for 15 h. Optical properties, crystalline structure, and surface roughness were analyzed and compared using analysis of variance (5% significance level).ResultsThere was no statistically significant effect of aging on translucency (p = 0.10), but CRA promoted the development of a high contrast ratio (p = 0.03). Aging did not cause significant color changes for HT (p = 0.65) or XT (p = 0.36). The proportion of monoclinic crystals increased to 40% for HT‐zirconia after HA and 5% after CRA. No monoclinic crystals were detected for XT groups. There was no effect of aging on surface roughness (p = 0.77).ConclusionsAlthough hydrothermal aging has been widely used to verify zirconia crystalline stability, it did not generate an effect similar to clinically related aging on the optical properties and crystalline structure of zirconia. HA affected the crystalline structure of HT‐zirconia, and CRA compromised the optical properties of XT zirconia.
Consumers' willingness to pay for safer, more environmentally friendly smoke flavored chicken breasts
Authors: Ellsworth Seth , Crandall Philip Glen , Seo Han‐Seok , O'Bryan Corliss A. 
Published: January 2023

AbstractBoneless, skinless chicken breasts comprise almost 30% of total poultry sales and poultry remains US consumers' protein of choice. This research sought to determine whether consumers of chicken would pay a premium for a smoked chicken breast that was healthier and produced with less of a negative impact on the environment. Two balanced consumer panel groups were presented with information on the two value prospects of smoked chicken prepared with liquid smoke. The order of presentation of the health claims and the environmentally friendly claims were reversed to measure the impact of the order of presentation on consumers' willingness to pay. An Nth type auction showed that health claims elicited a greater premium; the highest average premium was approximately $7 including the baseline price following the health claims for the liquid smoked chicken. The order of presentation of the information did not affect the results.Practical applicationsConsumers are willing to pay more for chicken that is deemed healthier and prepared with environmentally friendly ingredients.
Multistability and hysteresis in states of oral microbiota: Is it impacting the dental clinical cohort studies?
Authors: Mangal Utkarsh , Noh Kowoon , Lee Seeyoon , Cha Jae‐Kook , Song Je Seon , Cha Jung‐Yul , Lee Kee‐Joon , Kim Kwang‐Mahn , Kwon Jae‐Sung , Choi Sung‐Hwan 
Published: January 2023

AbstractIntroductionMicrobiome from a “healthy cohort” is used as a reference for comparison to cases and intervention. However, the studies with cohort‐based clinical research have not sufficiently accounted for the multistability in oral microbial community. The screening is limited to phenotypic features with marked variations in microbial genomic markers. Herein, we aimed to assess the stability of the oral microbiome across time from an intervention‐free “healthy” cohort.MethodsWe obtained 33 supragingival samples of 11 healthy participants from the biobank. For each participant, we processed one sample as baseline (T0) and two samples spaced at 1‐month (T1) and 3‐month (T2) intervals for 16S ribosomal RNA gene sequencing analysis.ResultsWe observed that taxonomic profiling had a similar pattern of dominant genera, namely, Rothia, Prevotella, and Hemophilus, at all time points. Shannon diversity revealed a significant increase from T0 (p < .05). Bray Curtis dissimilarity was significant (R = −.02, p < .01) within the cohort at each time point. Community stability had negative correlation to synchrony (r = −.739; p = .009) and variance (r = −.605; p = .048) of the species. Clustering revealed marked differences in the grouping patterns between the three time points. For all time points, the clusters presented a substantially dissimilar set of differentially abundant taxonomic and functional biomarkers.ConclusionOur observations indicate towards the presence of multistable states within the oral microbiome in an intervention‐free healthy cohort. For a conclusive and meaningful long‐term reference, dental clinical research should account for multistability in the personalized therapy approach to improve the identification and classification of reliable markers.
Being Wounded: Finitude and the Infinite in Jean Louis Chrétien and Gregory of Nyssa
Authors: Breedlove Thomas 
Published: January 2023

AbstractWounds appear throughout the writings of Jean‐Louis Chrétien and Gregory of Nyssa. Most well known in Chrétien's corpus is his description of prayer as a “wounded word,” a phrase that seeks to describe an ungraspable dimension of phenomenal life in which the contingency and groundlessness of finitude appear as gifts. Gregory, in turn, draws upon the language of wounding in the Song of Songs to describe the soul's ascent to God. The first two parts of this essay bring to light how, for both writers, woundedness characterizes human finitude and describes encounters with the infinite. The third part turns to Chrétien's phenomenology of touch and Gregory's account of Macrina's scar, taking up the question of how the wound of finitude relates to wounded flesh. While both writers use the language of woundedness to describe a reality that both precedes and opposes historical violence, it remains that the power of this language flows from historical and physical wounds. The final pages argue that in drawing upon while seeking to oppose such wounds, this image represents not a liminal case but the complexity and contingency that attends theological speech which—the image of the wound reminds—is of the flesh.
Localization and pathogenic role of the cysteine protease dentipain in Treponema denticola
Authors: Miyai‐Murai Yuri , Okamoto‐Shibayama Kazuko , Sato Toru , Kikuchi Yuichiro , Kokubu Eitoyo , Potempa Jan , Ishihara Kazuyuki 
Published: January 2023

AbstractThe Msp protein complex and the serine protease dentilisin are the best‐characterized virulence factors in Treponema denticola, the major etiological agent of chronic periodontitis. In addition to these outer sheath factors, the cysteine protease dentipain contributes to pathogenicity, but its secretion, processing, cellular localization, and role in T. denticola virulence are not fully understood. In this study, we found that full‐sized dentipain (74‐kDa) and the 52‐kDa truncated form of the enzyme are located, respectively, in the outer sheath derived from T. denticola dentilisin‐ and the Msp‐deficient mutants. Furthermore, dentipain was barely detected in the wild‐type strain. These results suggest that dentilisin and Msp, the major outer sheath proteins, are involved in the secretion and maturation of dentipain. Inactivation of the dentipain gene slowed the growth of T. denticola, and the effect was more profound in serum‐free medium than in serum‐containing medium. Several genes, including those encoding transporters and methyl‐accepting chemotaxis proteins, were differentially expressed in the dentipain‐deficient mutant. Furthermore, the mutant strain was more hydrophobic than the wild‐type strain. Finally, the mutant showed less autoaggregation activity and adhesion to IgG in a serum‐free medium than the wild‐type strain. These findings suggest that dentipain contributes to the virulence of T. denticola by facilitating adhesion and acquisition of nutrients essential for colonization and proliferation in the gingival crevice under serum‐rich conditions.