bluuebunny/crossref_metadata_2025_split huggingface dataset:
Climate warming in the Russian North: biomedical aspect
Authors: Solomennyi A. P. 
Published: January 2023

Objective. To summarize the data regarding the warming of climate in the Russian sector of the Arctic and the effect of this process on the population health.
Materials and methods. The search and review of official documents of the international organizations, Rosgidromet, the Ministry of Healthcare of the Russian Federation and other institutions as well as scientific publications with experimental data on the situation and plan of actions in conditions of the current changes in the Arctic climate.
Results. The data presented show that Siberia and Arctic warm up more strongly than the other regions of the planet. The temperatures in these regions grow twice as faster than the world average ones.
Conclusions. The problems of negative consequences of climate warming for Perm Krai are urgent since Gainsky, Kosinsky and Kochevsky regions are officially included in the list of the territories of the Extreme North. In Perm Krai, there is possible an increase in the number of weather phenomena and risks for health associated with them.
Risk factors of maternal and failed maternal mortality, prediction of severe obstetric conditions
Authors: Berseneva S. N. , Isaeva N. V. , Padrul M. M. , Cherkasova E. V. 
Published: January 2023

Objective. To determine the priority risk factors for maternal mortality (MM) and failed maternal mortality (FMM) on the basis of clinical and epidemiological features and to develop scientifically based patient-centered models for predicting severe obstetric conditions.
Materials and methods. Primary documentation of successful and dysfunctional maternal outcomes that occurred at the levels I, II, III of medical organizations in Perm and the territories of Perm Krai from 2007 to 2018. Using random sampling, two observation groups were formed: women with failed maternal mortality, deceased women and the control group. Analytical epidemiological "case-control" studies were carried out, which included the determination of confidence intervals, etiological accuracy using Epi Info and Excel 2016 MSO programs, a package of applied electronic tables Stat2015 of the author ( V.S. Sheludko, 20012016), the MedCalc 15.8 Portable program.
Results. Socio-behavioral, general somatic, obstetric-gynecological risk factors, the frequency of occurrence of which among women with failed maternal mortality was 1,44,3; 1,225,5; 1,17,6 times more often, and in the group of deceased mothers 1,99,0; 1,729,5; 2,89,0 times higher than in the group of healthy participants. The "indicators of maternal death" have been identified, which increase the risk of a failed maternal death turning into maternal death. Early clinical and laboratory signs of severe obstetric conditions are the following: high leukocyte intoxication index (LII), elevated levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), urea and creatinine, decreased levels of fibrinogen, prothrombin index (PTI), prolongation of thrombin time (TT). Infectious-inflammatory, hypertensive complications, comorbidity, a high percentage of premature births and, accordingly, severe perinatal conditions are significantly more common in groups with unfavorable outcomes.
Conclusions. In the course of the study, reliably significant risk factors were identified, on the basis of which scientifically based models for assessing the probability of developing critical obstetric conditions were worked out.
Blepharoplasty in Involutional Spastic Lower Lid Entropion
Authors: Ivolgina I. V. 
Published: January 2023

Background. The eyelids are movable folds that protect the eyeball from external influences and carry out a supporting function. A misalignment of the eyelids can seriously effect on the ocular function.Purpose. To evaluate the effectiveness of surgical treatment of spastic lower lid entropion.Patients and methods. The results of treating patients with eyelid entropion for the period from 2014 to 2021 were analyzed — 66 people, 85 operations. All patients with eyelid entropion underwent a standard ophthalmological examination and additional studies, which revealed the presence of a spastic component. The pathogenetically substantiated methods of surgical treatment were performed.Results and discussion. In all 69 cases, where operations were performed according to the Wheeler and Callahan method — the lower eyelid was in the correct position, changing the direction of tension of the circular muscle and the Riolan’s muscle, creating a duplicate of the muscles. The retractor was strengthened, which ensured the correct position of the eyelid. In 16 cases in recurrent entropion and the presence of blepharospasm caused by corneal changes, surgery was performed according to the Meek method. In the early period, in all cases, hyper effect was observed. In the late period, the hyper effect persisted in 4 cases (25.00 %), but the patients refused reoperation.Conclusions. Determination of the parameters of the lower eyelid state during examination makes it possible to identify the reasons for the development of entropion, the presence of a spastic component MRI or CT examination allows assessing the condition of the eyelid retractor objectively. In patients with spastic entropion, Wheeler and Kallahan surgeries that eliminate the spastic component provide a stable result. In patients with spastic recurrent entropion, accompanied by blepharospasm, the Meek’s surgeries in all cases provide a stable result. The disadvantage of this operation is the presence of hyper effect in 100 % of cases in the early period, which persisted in the late postoperative period in 25 % of cases.
Features of Tonometric Indicators Obtained by the Corneal Biomechanical Properties Analyzer Using Corneal Imaging Technology CorVis ST, Oculus in Real Clinical Practice
Authors: Apostolova A. S. , Malyshev A. V. , Sergienko A. A. , Oparina A. E. , Slavova M. A. 
Published: January 2023

Objective: to analyze the tonometric data, obtained with standard contactless tonometry and corneal-compensated tonometry, examined by the Oculus CorVis ST device in different groups of patients of the Tri-Z Krasnodar Clinic.Patients and Methods. The study included 42 eyes of patients, with glaucoma — 55 %, with suspected glaucoma — 45 %, mean age — 63.19 ± 1.7 years, men were 20 (47.5 %), women — 22 (52.5 %), the central corneal thickness was 554.43 ± 5.28 microns. Corneal tomography and biomechanical parameters were measured using Pentacam (Oculus) and Corvus ST, respectively.Results. IOP in people aged over 60 years was lower according to CorVis ST (Po 22.07 = 2.25, Pcс 18.63 ± 1.30, p = 0.007). IOP differed only in patients with a CCT of more than 580 µm (Po 22.4 ± 2.9, Pcc 18.21 ± 2.16, p = 0.012). IOP in patients with glaucoma was Ро 26.19 ± 3.5 and Рсс 21.3 ± 2.0, p = 0.008, without glaucoma — Ро 17.83 ± 9.60; Pсс 16.1 ± 5.5; p = 0.063. IOP in patients with compensated glaucoma Ро 17.34 ± 1.10, Pсс 16.6 ± 1.1, p = 0.354, with decompensated Ро 42.78 ± 6.8, Pсс 30.08 ± 4.10, p = 0.005. In the initial stage of glaucoma, Рo 22.5 ± 2.3, Рсс 20.0 ± 1.0, p = 0.297, in the advanced stage — Рo 20.7 ± 2.7, Рсс 17.6 ± 1.9, p = 0.027.Conclusion. Standard non-contact tonometry can be used in persons aged under 60 years, persons without glaucoma and with initial compensated glaucoma. In all other cases, the Oculus CorVis ST values are more accurate.
Failed Induction of Labor and Associated Factors Among Women Who Undergone Induction of Labor in Jimma Medical Center, Ethiopia: A Hospital-Based Cross-Sectional Study
Authors: Kitaba Kebenesa Angasu , Hussein Hanan Osman , Gadisa Tariku Bekela , Gonfa Mosisa Ebisa 
Published: January 2023

BACKGROUNDAlthough induction of labor is intended to achieve a safe vaginal delivery, its process is not always successful. Failed induction of labor leads to an increased risk of complication for both mother and fetus. Thus, this study aimed to assess the proportion of failed induction of labor and associated factors among women who undergone induction of labor from September 1, 2019 to August 31, 2020 in Jimma Medical Center (JMC), southwest Ethiopia.METHODSA hospital-based retrospective cross-sectional study was conducted on 243 charts of women who had induction of labor in JMC selected by a simple random sampling method from January 10 to 30, 2021. The collected data were entered into Epi-data version 4.2 and analyzed by SPSS version 23. Bivariate and multivariable logistic regression analyses were done to test the association. Adjusted odds ratio at 95% confidence interval (CI) andP-value <.05 was used to ascertain statistical significance.RESULTSThe proportion of failed induction of labor in JMC was 16.9%. Maternal age ≥ 30 years (AOR 7.57; 95%CI = 2.88, 19.9) at (P-value = .000), elective induction (AOR .39; 95% CI = .16, .98) at (P-value = .045), and unfavorable bishop score (AOR 6.94; 95%CI = 2.35, 20.4) at (P-value = .000) were factors statistically significantly associated with failed induction of labor.CONCLUSIONSThe proportion of failed induction of labor was relatively low in the study area. Advanced maternal age, elective induction, and unfavorable bishop score were associated with failed induction of labor. Thus, the hospital should strictly follow the protocol for induction of labor, and candidates of emergency induction of labor should be counseled thoroughly so as to be well prepared psychologically for the labor thereby reducing the risk of failed induction.
Career Transitions Caused by Chronic Illness: A Career Construction Perspective
Authors: Hill Julie C. , Stokes Lindsey E. , Higgins Kristin K. 
Published: January 2023

Purpose:People living with chronic illness face significant challenges with employment. This study explores the impact of participating in the Career Construction Interview (CCI) on the career exploration of individuals facing a forced career transition due to the onset or exacerbation of a chronic illness.Method:An instrumental multiple case study design was used in this qualitative study. A purposeful, homogeneous sample of three female adults was used to gain multiple perspective of forced career transitions. The participants were within 2 years of their diagnosis or exacerbation of one or more chronic health conditions and had to change their career because of the impact of their condition(s).Results:Eight open codes and five axial codes were discovered through the process of constant comparative analysis. For this study one open code (CCI experience) and five axial codes will be discussed.Conclusions:This study found patterns related to chronic illness and career and that the Career Construction Interview was helpful to the participants in assisting them with making decisions about potential careers and options for employment. Implications for rehabilitation counseling practice and suggestions for future research.
Impact of COVID-19 on People With Aphasia: Emerging Rehabilitation Needs
Authors: Sandberg Chaleece W. , Niemkiewicz Joanne K. , Kubat Anne Marie , Conyers Liza M. 
Published: January 2023

Purpose:The purpose of this article is to address an emerging issue in rehabilitation counseling: The effect of the COVID-19 pandemic on people with aphasia (PWA).Method:Based upon a review of the literature this article provides an overview of (a) COVID-19 and emergent aphasia-related disability, (b) COVID-19 effects on stroke and aphasia services, (c) COVID-19 effects on mental health and employment of PWA.Results:This review of the impact of COVID-19 on PWA highlights the increased and emerging needs for rehabilitation counseling services related to an anticipated increase in incidence of aphasia related to COVID-19 illness and secondary impact of medical care for this population.Conclusion:The impact of COVID-19 on aphasia care in rehabilitation settings underscores the need for increased interprofessional education and collaboration to address the many gaps in aphasia care. Likewise, interdisciplinary research focused on rehabilitation outcomes in aphasia is needed to provide a foundation for evidence-based practice that conforms to the WHO-ICF framework.
As Terras Indígenas, a Proteção nos Termos da Constituição Vigente e Normas Infraconstitucionais, sua Demarcação e o Embate na Exploração Destas
Authors: Lima João Batista Guimarães de , Oliveira Joveny Sebastião Cândido de 
Published: January 2023

A Constituição Federal/1988, como em nenhuma outra, protege os índios, assim como em normas infraconstitucionais. Nos termos da CF/1988, é competência privativa da União legislar sobre populações indígenas. Outrossim, o texto constitucional reconhece aos índios à organização social, costumes, línguas, crenças e tradições e às terras que tradicionalmente ocupam, competindo à União demarcá-las, proteger e fazer respeitar todos os seus bens.
A Constituição Federal diz em seu art. 231 que, são terras tradicionalmente ocupadas pelos índios as por eles habitadas em caráter permanente, as utilizadas para suas atividades produtivas, as imprescindíveis à preservação dos recursos ambientais necessários ao bem-estar e as necessárias à sua reprodução física e cultural, segundo seus usos, costumes e tradições. Tais terras, cabe-lhes o usufruto exclusivo das riquezas do solo, dos rios e dos lagos nelas existentes. Tais terras, que constituem patrimônio da União, são inalienáveis e indisponíveis, e os direitos sobre elas, imprescritíveis. O aproveitamento dos recursos hídricos, incluídos os potenciais energéticos, a pesquisa e a lavra das riquezas minerais em terras indígenas, só pode ser efetivado com autorização do Congresso Nacional.
Анализ динамики эпидемического процесса COVID-19 в мире за неделю с 31.12.2022 г. по 06.01.2023 г.
Authors: Зимирова Анастасия , Поспелов Михаил , Иванова Александра , Дмитриева Людмила , Чумачкова Елена , Карнаухов Игорь , Щербакова Светлана , Кутырев Владимир 
Published: January 2023

В обзоре представлен анализ эпидемиологической ситуации в странах мира по
COVID-19, за неделю с 31.12.2022 г. по 06.01.2023 г.
2D Surface Roughness Quantification for Enhanced Petrophysical Applications
Authors: Singer Gabriela , Ma Shouxiang Mark , Chen Songhua , Eid Mahmoud 
Published: January 2023

Summary
Surface roughness is an essential rock parameter affecting petrophysical properties that are surface sensitive such as characterization of pore structure and wettability. For instance, Wenzel’s contact angle formula for rough surfaces requires knowledge of the surface roughness, and surface roughness is expected to speed up the aging of cores in crude oil for wettability restoration. In addition, proper quantification of surface roughness is critical for obtaining representative, roughness-independent, pore sizes for applications such as prediction of permeability and interpretation of capillary pressure curves.
Intuitively, a surface is better characterized in 2D than in 1D. This 2D study is a continuation and enhancement of the previous 1D work, recently published in the SPE Journal (Ma et al. 2021). In this current paper, a comprehensive investigation of 1D vs. 2D surface roughness measurements is conducted to evaluate and cross validate the two approaches. In this study, surface roughness is measured on 26 carbonate rock samples by laser scanning confocal microscopy (LSCM), where both the 1D absolute increment surface roughness, Sr, and the 2D interfacial area ratio of surface roughness, Sdr, are reported. As expected, the results indicate that surface roughness characterized by 2D Sdr has a greater dynamic range than the 1D Sr measurement, i.e., the 2D Sdr provides a more representative characterization of surface roughness.
A detailed account of methodologies, assumptions, limitations, validation, and applications of the 1D and 2D surface roughness characterization is documented in this paper. To extract the roughness features present on rock grain surfaces, effects of de-spiking and filter length, used to eliminate pore-size effects, are investigated. For specific applications of surface roughness corrected pore-size estimation from nuclear magnetic resonance (NMR) measurements, differences in length scales of surface roughness are compared between LSCM measurement and that derived from NMR diffusion-T2 plus BET (Brunauer-Emmett-Teller) surface area. The surface roughness-corrected NMR pore-size distribution is also validated against the pore-size distribution obtained from the measurement of micro-computed tomography (CT) scanning.
An Unusual Case of Pancytopenia With Hepatosplenomegaly Case Report
Authors: Alam Farid 
Published: January 2023

Abstract
BACKGROUND
Gaucher’s disease is one of the most common lysosomal storage diseases characterized by hematologic abnormalities, organomegaly, and skeletal involvement. It is caused by reduced activity of the enzyme acid β-glucosidase which is encoded by a gene on chromosome 1q21-q311. There are 3 clinical subtypes distinguished by the presence or absence and progression of neurologic manifestations: type 1 or the adult, non neuronopathic form; type 2, the infantile or acute neuronopathic form; and type 3, the juvenile or subacute neuronopathic form3. Here we report a case of Gaucher’s disease that presented with pancytopenia and splenomegaly. We present this case to emphasize the importance of considering storage disorders like Gaucher’s disease when evaluating a case of unexplained pancytopenia and organomegaly even in adults
CASE PRESENTATION
A 20 year old female presented with generalised weakness and easy fatigability, menorrhagia and dragging sensation in the left upper quadrant of abdomen. On physical examination, She had massive splenomegaly with firm consistency, regular margin and smooth surface and a non tender, mild hepatomegaly. Lab investigations showed pancytopenia. Bone marrow biopsy was done which revealed hypercellular marrow with clusters of ovoid macrophages with abundant fibrillary cytoplasm and round eccentric nucleus (gaucher cells). To confirm the diagnosis of Gaucher’s disease (Type 1), β-glucosidase enzyme assay by fluorometry method was done which showed β-glucosidase level of 0.51 nmol/hour/ml (normal value >2 nmol/hour/ml). Final diagnosis was G.D (type-1).
CONCLUSIONS
This case emphasises the importance of considering storage disorders like Gaucher’s disease in patients presenting with pancytopenia and organomegaly even in adulthood. A high index of suspicion is needed for early diagnosis so that timely and appropriate treatment can be administered.
Novel Underwater Continuum Robot: Structural Design, Theoretical Modeling and Experiments
Authors: Ru Changxin , Zang Hongbin , Gao Yuan , Yin Qiang , li Chengjia , Zhou Jun , Huo Jianwen , Yuan Weifeng 
Published: January 2023

Abstract
Continuum robots have high adaptability to narrow underwater environments, because of their unique redundant degree of freedom (DOF) and post drive integration design. However, they need multiple motors to control redundant DOF, which increases the manufacturing cost and control difficulty. This paper studies and proposes a continuum robot suitable for underwater operations. The robot adopts the drive mode of the diagonal coupling gear system to realize the control of two ropes by a single motor and reduce the number of motors from 12 to 6. On this basis, motion can be achieved by rope traction on different joint groups. The kinematic model of the planar circular arc method is established to reduce the complexity of the inverse kinematics of continuous joints and improve the solving speed. The motion posture and working space are obtained through the simulation analysis. Finally, the robot’s function and load test with an arm length of 609 mm are demonstrated, and the air tightness and water tightness tests are carried out at the same time, that verify the rationality of the structure and control of the continuum robot for the underwater operation.
Targeting transforming growth factor alpha to recruit newly generated neuroblasts in cortical brain injuries
Authors: Gómez-Oliva Ricardo , Geribaldi-Doldán Noelia , Domínguez-García Samuel , Pardillo-Díaz Ricardo , Martínez-Ortega Sergio , Oliva-Montero José María , Pérez-García Patricia , Cózar Francisco J García , Muñoz-Miranda Juan Pedro , Sánchez-Gomar Ismael , Nunez-Abades Pedro , Castro Carmen 
Published: January 2023

Abstract
Background
Neurogenesis is stimulated in the subventricular zone (SVZ) of mice with cortical brain injuries. In most of these injuries, newly generated neuroblasts attempt to migrate toward the injury, accumulating within the corpus callosum not reaching the perilesional area.
Methods
We use a murine model of mechanical cortical brain injury, in which we perform unilateral cortical injuries in the primary motor cortex of adult male mice. We study neurogenesis in the SVZ and perilesional area at 7 and 14 dpi as well as the ex pression and concentration of the signaling molecule transforming growth factor alpha (TGF-α) and its receptor the epidermal growth factor (EGFR). We use inhibitors of EGFR to promote neurogenesis in brain injuries.
Results
We show that microglial cells that emerge within the injured area and the SVZ in response to the injury express high levels of TGF-α leading to elevated concentrations of TGF-α in the cerebrospinal fluid. Thus, the number of neuroblasts in the SVZ increases in response to the injury, a large number of these neuroblasts remain immature and proliferate expressing the epidermal growth factor receptor (EGFR) and the proliferation marker Ki67. Restraining TGF-α release with a classical protein kinase C inhibitor reduces the number of these proliferative EGFR+ immature neuroblasts in the SVZ. In accordance, the inhibition of the TGF-α receptor, EGFR promotes migration of neuroblasts toward the injury leading to an elevated number of neuroblasts within the perilesional area.
Conclusions
our results indicate that in response to an injury, microglial cells activated within the injury and the SVZ release TGF-α, activating the EGFR present in the neuroblasts membrane inducing their proliferation, delaying maturation and negatively regulating migration. The inactivation of this signaling pathway stimulates neuroblast migration toward the injury and enhances the quantity of neuroblasts within the injured area. These results suggest that these proteins may be used as target molecules to regenerate brain injuries.
Energy-saving High-bandwidth Perovskite Nano-encoder
Authors: Xie Wei , Liang Shuang , Zhong Yichi , Tang Bing , Wang Qiangqiang , Hu Yongsheng , Wang Zhenyu , Zhang Long , Dong Hongxing , Xu Hongxing 
Published: January 2023

Abstract
Optical coding has been widely applied in communication and data processing fields due to its practical and powerful characteristics, such as high transmission rate and operation convenience. However, improvements in the loading information capacity of optical encoders, always cause more energy consumption. It is a challenge to realize an optical encoder that combines energy savings, high bandwidth, and miniaturization. Here, we report both the concept and the demonstration of a perovskite nano-encoder with an 84% energy-saving efficiency and a tuneable bandwidth up to 200 GHz. The way to code the radiative dynamics of the light source could reduce the unnecessary energy consumption from the initial stage through the control of radiation core. Moreover, the miniature encoder generates code sequences of good coherence, stimulating the development of perovskite-based optical microchips for ultrafast information processing.