bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of usage of immunity boosters among the citizens of Pune district during the COVID-19 pandemic
Authors: Sajith Manjusha , Danole Ritika Rajendra , Shaji Jilu Treasa , Kuruvila Ansee 
Published: June 2023

Introduction:
Post the coronavirus disease (COVID-19 pandemic), there was a spike in demand for immunity boosters, leading to the irrational use of supplements. To assess the usage of immunity boosters among the citizens of Pune City and correlate the side effects associated with supplements.

Material and Methods:
A cross-sectional study was conducted from September 2020 to May 2021 in Pune. Data, such as demographic, supplement intake (allopathic, homeopathic, and ayurvedic/home remedies), duration, frequency of supplements, and side effects associated with supplements, were collected through a personal interview and e-form circulation. The correlation of the immunity boosters with the side effects was done using Karl Pearson's Correlation test in SPSS software version 22.0.

Results:
Out of 1006, the ayurvedic supplements/home remedies were preferred by 906 (98%) allopathic supplements by 599 (65%) and homeopathic supplements by 256 (28%) participants. The commonly reported side effects were acidity (37%), headache (29.6%), nausea (9%), loss of appetite (8.8%), diarrhea (7%), stomach ache (6%), cough (5.6%), and constipation (4.1%). These side effects had a weak positive linear proportionality with ayurvedic supplements such as amla (r = 0.162), Giloy Vati (r = 0.139), turmeric (r = 0.108), and Kadha (r = 0.102); also, Eupatorium perfoliatum, Vitamin C, and Vitamin D showed a linear proportionality with loss of appetite (r = 0.15), headache (r = 0.12), and cough (r = 0.12), respectively. A higher incidence of side effects such as nausea (r = 0.267), diarrhea (r = 0.243), headache (r = 0.164), and acidity (r = 0.113) was observed when supplements were taken for 6 months.

Conclusion:
Most participants were on immunity boosters during the COVID-19 pandemic. The study concluded that using immunity boosters in excess or for more than 6 months causes side effects, the most recurrent ones being acidity, headache, nausea, and lack of appetite.
Feasibility and Scope of Teledentistry Services during the COVID-19 Pandemic – A Cross-Sectional Study
Authors: Jain Swati , Mohanty Vikrant 
Published: June 2023

Introduction:
COVID-19 pandemic has influenced health-care utilization globally accentuating oral disease burden. This has reinforced the role of telemedicine. However, being technologically sensitive; the concept is still not popular. Hence, the present study aims to assess the scope and feasibility of teledentistry services of a Mobile Dental Clinics.

Methodology:
Teledentistry services were provided to the old patients of Mobile Dental Clinic Project for follow-up care from May 2021 to June 2021. Contact details of the patients were retrieved and were contacted for teleconsultation services using smartphones. Data were recorded through a prestructured digital outpatient department and feedback form.

Results:
A total of 813 active calls were made to provide teledentistry services. The response rate was 26.33% (n = 214). Around 78.5% (n = 168) of the study respondents did not have any current chief complaint related to oral health. Those who suffered from some ailment (11.2%) complained majorly of “dental pain.” Around 34.6% (n = 74) still required further dental treatment. The majority (97.7%) were satisfied with the teledentistry services provided.

Discussion:
Mostly, the patients could not be contacted due to COVID-19-related lockdown and migration from the city. From the patients who were followed up, 21.5% reported having some dental complaint. This clearly showed that these patients had received dental treatment even during pandemic. Furthermore, the felt need in the community was quite high leading to health-seeking behavior previously.

Conclusion:
In the view of COVID-19 preventive measures, it is advocated that teledentistry services should be implemented to improve oral healthcare outreach.
Analysis of Epstein–Barr virus infection in oral potentially malignant disorders and oral cancer: A cross-sectional study
Authors: Pankam Jintana , Lapthanasupkul Puangwan , Kitkumthorn Nakarin , Rungraungrayabkul Dulyapong , Klongnoi Boworn , Piboonniyom Khovidhunkit Siribang-on 
Published: June 2023

Abstract

Aims and Objectives:
The primary objective of this study is to determine the prevalence of Epstein–Barr virus (EBV) in oral potentially malignant disorders (OPMDs) and oral cancer (OC) in a group of Thais using polymerase chain reaction (PCR) and Epstein–Barr encoding regions (EBERs) in situ hybridization (ISH). The secondary objective is to investigate the risk factors of OC and the association between the presence of EBV and risk factors of OC/site of oral lesions.

Materials and Methods:
Sixty-one participants attending the screening project for OC and OPMDs at the Northeastern district hospitals of Thailand were recruited. Information related to risk factors and biopsy tissues for histopathological diagnosis was collected. Sixty-seven paraffin tissue blocks, including 52 OPMDs and 15 OC specimens, were investigated for EBV infection, using PCR analysis with latent membrane protein-1 (LMP-1) primer and EBERs ISH. Pearson’s Chi-square or Fisher’s exact test was used to analyze the differences in variables between participants with OPMDs and OC, as appropriate. The association between EBV infection and related risk factors was analyzed using logistic regression with a significant level at 0.05.

Results:
Using PCR analysis, 8 of 67 specimens (11.94%) were positive for LMP-1. Three cases of OPMDs were positive for both LMP-1 PCR and EBERs ISH. Regarding risk factors of OC, the two most common risk factors were betel nut chewing (52.46%) and working in sunlight (42.62%). The habit of taking alcohol was significantly different between the OC and the OPMDs groups (p = 0.009). The association between LMP-1 and the lesion at the tongue was statistically significant, with odds ratio = 4.900 (95% confidence interval = 1.046–22.943; p = 0.044).

Conclusions:
The prevalence of EBV infection in this group of participants was low. However, OPMDs at the tongue exhibited a significant association with EBV infection.
Traumatic Spinal Cord Injuries: An Institutional Experience
Authors: Velho Vernon L. , Skhandeshwaran P. , Kharosekar Hrushikesh 
Published: June 2023

Background:
Traumatic Spinal cord injuries are an important health burden taking heavy toll on life and livelihood. Early institution of treatment has best chance of nursing patient back to health. Even with timely intervention this disease has high mortality, morbidity and disability rates.

Objective:
The objective of this study was to analyze the epidemiological aspects and evaluate the outcomes and efficacy of the existing treatment modalities of traumatic spinal cord injuries.

Marterials and Methods:
Prospective study was conducted on all the cases of traumatic spinal cord injuries admitted at the institutional level between the years of 2019 January and 2022 January. Patients’ records were analyzed for epidemiological data, treatment modalities, preoperative baseline data, immediate postoperative outcomes, outcomes at discharge, and follow-up (6-month follow-up).

Results:
There were a total of 168 cases of traumatic spinal cord injury (SCI); of which 103 were cervical and 65 were thoracolumbar with a male: female ratio of 2.4:1 with the mean age being around 37 years. Road/railway traffic accidents account for the most common (42.6%), followed by fall down from height (26%). Eighty-one (48.21%) had American Spinal Injury Association Grade A injury. Thirteen (7%) were able to be discharged from the hospital with no deficits. Sixty-seven (39.8%) was the mortality rate. The statistics are in line with national data for traumatic SCI. Extensive research is being undertaken for newer modalities of treatment to improve outcomes.

Conclusion:
Traumatic spinal injuries are improtant health burden. Early prompt and appropriate treatment can prevent high mortality, morbidity and disability.
A correlation of 8-hour and 12-hour with 24-hour urinary protein among pregnant women with preeclampsia in a teaching hospital in South-Western Nigeria
Authors: Akindele R.A. , Omopariola S.O. , Adeyemo A.T. , Afolabi B.A. , Awodele K. , Folami E.O. , Adeyemo A.T. 
Published: June 2023

Background and Objective: Proteinuria is one of the cardinal features of preeclampsia, which is a common and potentially severe complication of pregnancy. This study sought to determine how the quantitative measurement of urine protein from 8-hour and 12- hour samples correlate with that of a 24-hour sample in diagnosing preeclampsia.
Materials and Methods: 52 eligible pregnant women with preeclampsia were recruited between April 2017 and April 2018. For each patient, having emptied the bladder at 0 hour, urine was collected into three different containers (containers 1, 2, 3) at 8th hour, 12th hour and 24th hour ensuring that the bladder was emptied into each container at hours 8, 12 and 24. Volumes of 8 hours urine (volume in container 1), 12 hours urine (total volume in containers 1 and 2), and 24 hours urine (total volumes in containers 1, 2 and 3) were measured and 5 ml aliquot respectively obtained from each sample for colorimetric analysis of urinary protein. Data was analyzed using the EPI Info software
Results: A total of 52 patients completed the study. The mean gestational age was 33+ 2.82weeks. The mean 8-hour, 12-hour and 24-hour urinary protein values were 2.1+1.53, 2.3+1.52 and 3.1+1.89 respectively. There were significant correlations between the protein values of 8-and 12-hour urine samples with those of 24-hour urine samples
Conclusion: 8-hour and 12-hour values of urine protein correlated positively with values in 24-hour samples and may be useful for initial assessment of cases of preeclampsia for prompt interventions.
Graphics by Viktor Khvostenko
Authors: Сидорова О.В. 
Published: June 2023

Статья посвящена графике художника Виктора Михайловича Хвостенко, который живет и работает в городе Бийске Алтайского края. Материалом исследования послужили работы, представленные на персональной выставке художника в апреле-мае 2023 года в Государственном художественном музее Алтайского края. Статья вводит в научный оборот произведения мастера и его комментарии и воспоминания, записанные автором статьи в интервью, которое хранится в архиве музея. Виктор Хвостенко учился у лучших представителей современного сатирического рисунка, работал под руководством известных московских художников-сатириков Е. Гурова, Е. Шукаева, Ж. Ефимовского, сотрудничал с редакциями сатирических журналов «Крокодил», «Перец», «Чаян». На выставке в художественном музее «Здравствуйте, соседи!» (2023) было представлено более 40 работ художника: иллюстрации к произведениям Ф.М. Достоевского, В.М. Шукшина, графические серии «Телефон-автомат», «Аэропорт», «Деревенский мостик», «Будьте здоровы!», посвященные детской тематике. Серия рисунков художника «Деревенский мостик» была отобрана региональным выставкомом для экспонирования на межрегиональной выставке «Сибирь – XIII» (Барнаул, 2023).
The article presents a study of graphics by the artist Viktor M. Khvostenko, who lives and works in the Altai Krai. The research material is the works presented at the artist's personal exhibition in April-May 2023 at the State Art Museum of Altai Krai. Viktor Khvostenko is a thoughtful and subtle interpreter of reality who looks at the world with a smile; this is his life and professional credo. He studied with the best representatives of modern satirical drawing. In 1986–1989 he actively collaborated with the editorial offices of the satirical magazines “Crocodile”, “Pepper”, “Chayan”. He worked under the guidance of famous Moscow satirical artists: Evgeny Gurov, Evgeny Shukaev, and Joseph Efimovsky. The result of such cooperation was participation in the All-Union Exhibition of Satire and Humor in 1986. More than 40 works of the artist were presented at the personal exhibition “Hello, neighbours!”. These were illustrations to the works of F.M. Dostoevsky, V.M. Shukshin, graphic series “Pay phone”, “Airport”, “Village Bridge”, “Be healthy!”, dedicated to children's themes. A series of drawings by the artist “Village Bridge” was selected by the Interregional Exhibition “Siberia – 13th” (Barnaul, 2023).
Pemberdayaan Komunitas Herbal Medicine Class di Tangerang Selatan dalam Meningkatkan Kesehatan Keluarga
Authors: Adi Lukas Tersono 
Published: June 2023

ABSTRAKLatar Belakang: Lebih dari dua tahun bencana COVID-19 berlalu menyisakan pekerjaan rumah semua bangsa di dunia, termasuk pemerintah Indonesia. Pemerintah telah berusaha semaksimal mungkin dalam mengendalikan penyebaran penyakit. Upaya kesehatan berbasis masyarakat di Indonesia sebanyak 63.6% yang aktif. Hal ini menandakan potensi yang belum tergali secara optimal dalam perlindungan kesehatan masyarakat secara menyeluruh.Tujuan: Penelitian ini bertujuan untuk menelaah partisipasi masyarakat dalam pemberdayaan dan pengelolaan kesehatan secara mandiri dalam keluarga.Metode: Menggunakan metode kualitatif berbentuk studi kasus menggunakan data yang diambil dari sumber data sekunder berasal dari pengelola komunitas Herbal Medicine Class, observasi, wawancara dengan 12 informan. Analisis data dilakukan dengan menggunakan teknik analisa konten dimana peneliti menginterpretasikan penelitian sesuai dengan masalah penelitian.Hasil: Komunitas memberikan ruang partisipasi masyarakat terhadap sasaran yang belum tercapai melalui pendekatan teknologi, kearifan lokal dan suasana kondusif di masyarakat. Hal ini justru akan membantu proses penyembuhan, peningkatan kapasitas, perlindungan kesehatan, termasuk panutan sebagai fasilitator dan teman. Keberhasilan pemberdayaan masyarakat terletak pada model, komitmen dan pemberdayaan.Kesimpulan: Pemberdayaan komunitas dapat mencapai kedaulatan kesehatan dengan mengutamakan keluarga menciptakan suasana kondusif, selalu menghargai kualitas hidup dan kearifan lokal serta keteladanan. AbstractBackground: More than 2 years since the COVID-19 disaster has passed, it has left homework for all nations in the world, including the Indonesian government,which has made every effort to control the spread of the disease. At that time community-based health efforts in Indonesia were 63.6% active, there was potential that had not been explored optimally in protecting public health as a whole.Purpose:Observing community participation in health empowerment and processing independently within the family.Method: Using qualitative methods in the form of case studies using data taken from secondary data sources from Herbal Medicine Class community manager,observations, interviews with 12 informants.Data analysis was carried out using content analysis techniques in which the researcher interpreted the research according to the research problem.Results:The community provides space for community participation for targets that have not been reached through a technological approach, local wisdom,and a conducive atmosphere in society, in fact helping the healing process, capacity building, health protection, including role models as facilitators and companions. The success of community empowerment lies in the commitment and empowerment model.Conclusion:Community empowerment can achieve health sovereignty by prioritizing the family, creating a conducive atmosphere,always respecting the quality of life and local wisdom and role models.
SIKAP HKBP TERHADAP OKULTISME DAN EKSORSISME DALAM MASYARAKAT BATAK TOBA: KAJIAN ATAS PRAKTIK OKULTISME DI HKBP NAULI DANOHORBO
Authors: Sihombing Jhon Ferdinand , Sitanggang Asigor P. 
Published: June 2023

Perjumpaan Gereja dengan budaya memungkinkan terjadinya penerimaan atau penolakan gereja terhadap budaya. Gereja HKBP salah satu gereja kesukuan di Indonesia yang menerima dan menjaga tradisi Batak Toba. Penerimaan Gereja HKBP terhadap budaya telah disertai dengan larangan dan pengajaran yang tertuang dalam buku Konfessi dan Ruhut Parmahanion Paminsangon (RPP), namun masih ada jemaat yang melaksanakan praktik okultisme. Tulisan ini bertujuan mempercakapkan sikap Gereja HKBP saat ini dan di waktu yang akan datang terhadap praktik okultisme dan eksorsisme dalam masyarakat Batak Toba. Penulis akan menggunakan metode kualitatif dengan studi kepustakaan, yaitu upaya kontekstualisasi berbasis teori Stephen B. Bevans khususnya model sintesis dan berdasarkan pandangan Richard Niebuhr tentang Kristus dan Kebudayaan, Edgar H. Schein tentang struktur kebudayaan dan Martin Luther tentang Eksorsisme. Kajian ini menemukan bahwa tradisi Batak Toba mengandung nilai positif dan juga nilai negatif, oleh karena itu kajian ini menawarkan bahwa Gereja perlu melakukan kajian ulang terhadap budaya sehingga ditemukan tradisi yang benar, dan Gereja harus ambil bagian dalam praktik Eksorsisme.
The effect of zaleplon on metabolic changes in neurotransmitters and toxic effects in Danio fish
Authors: Volkova Alla Andreevna , Kalekin Roman Anatolievich , Orlova Alevtina Mikhailovna , Pavlova Albina Zakharovna , Astashkina Olga Genrikhovna , Pavlov Andrey Leonidovich 
Published: June 2023

Introduction. Z-drugs are a group of “non-benzodiazepine” drugs with the main mode of action regulating sleep behavior in humans through exposure to GABA receptors. There are reports indicating the toxic effects of overdose and abuse of zaleplon. However, information on the effect of Z-drugs on neurotransmitter levels is scarce.
The aim of this study was to study the effect of zaleplon exposure on neurotransmitter levels in the larvae of Danio fish using targeted metabolomics.
Material and methods. 4-hour exposure to zaleplon in concentrations of 0.1, 1.0, 10, 100 and 1000 μg/l was carried out on the larvae of Danio fish. Intervention groups were compared with control groups. Each group consisted of 20 larvae of Danio fish. Neurotransmitters and their metabolites were measured using high-performance liquid chromatography combined with tandem mass spectrometry (HPLC-MS/MS).
Results. Twenty-two metabolites associated with neurotransmission were quantified. Significantly increased metabolites were tryptophan, serotonin, 5-hydroxyindolacetic acid, acetylserotonin, epinephrine and choline. Significantly reduced metabolites were 5-hydroxytryptophan, 5-methoxytryptamine, dopamine, normetanephrine, metanephrine, kynurenine, 3-hydroxykinurenine, anthranilic acid and gamma-aminobutyric acid.
Limitation. When studying metabolic changes in neurotransmitters and toxic effects in Danio fish, the results of a group of 20 larvae were analyzed, which is a sufficient sample to state the results obtained.
Conclusion. Exposure to zaleplon caused metabolic changes in the concentrations of neurotransmitters associated with most major neurotransmitter systems.
UJI ANTIOKSIDAN KOMBINASI EKSTRAK ETANOL DAUN ALPUKAT (Persea americana Mill.) DAN DAUN JAMBU BIJI (Psidium guajava L.) METODE DPPH DAN FRAP
Authors: Douw Dollince Doumau , Wardani Tatiana Siska 
Published: June 2023

Radikal bebas (radikal bebas) adalah suatu senyawa atau molekul yang mengandung satu atau lebih elektron yang tidak berpasangan pada orbital luarnya. Semua bentuk gangguan tersebut dapat memicu munculnya berbagai penyakit seperti penyakit degeneratif hingga kanker. Oleh karena itu dilakukan penelitian yang bertujuan untuk mengetahui aktivitas antioksidan kombinasi ekstrak etanol 96% daun alpukat (Persea americana Mill.) dan daun jambu biji (Psidium guajava L.) sebagai antioksidan ditinjau dari kapasitas peredaman radikal bebas pada dua ekstrak tersebut dibandingkan dengan larutan standar Vitamin C dengan konsentrasi seri secara kombinasi kedua ekstrak etanol 96% manggunakan metode DPPH (2,2-difenil-1-pikrilhidrazil) dan FRAP ( FreecReducing antioxidant power) secara Spektrofotometri UV/Visibel. Hasil uji antioksidan dari kombinasi ekstrak daun alpukat dan daun jambu biji menunjukkan pada metode DPPH nilai IC50 89,282 ppm mempunyai antioksidan aktif, FRAP IC50 47,795 ppm mempunyai antioksidan sangat aktif.
Kata kunci: Daun alpukat, Daun jambu biji, Uji antioksidan, DPPH, FRAP
Uji Aktivitas Antibakteri Fraksi n-Heksan, Etil Asetat, Air Daun Rambutan (Nephelium lappaceum L) Terhadap Bakteri Escherichia coli ATCC 25922
Authors: Kayogop Ana Berlinda 
Published: June 2023

Salah satu obat tradisional dari tanaman yang sering digunakan adalah daun rambutan (Nephelium lappaceum L). yang secara tradisional masyarakat menggunakan daun rambutan sebagai alternatif pengobatan sebagai antibakteri.. Bakteri yang menjadi penyebab diare salah satunya adalah Escherichia coli. Penelitian ini bertujuan untuk mengetahui apakah aktivitas antibakteri fraksi n-heksan, etil asetat, air daun rambutan (Nephelium lappaceum L) terhadap pertumbuhan bakteri uji Escherichia coli ATCC 25922 dengan menggunakan metode dilusi dan difusi dengan konsentrasi 2,5%, 5%, 10%, 20%, 40% serta dengan kontrol positifnya adalah Ciprofloxacin dan kontrol negatifnya adalah DMSO 1%. Hasil dari pengujian ini yaitu Zona hambat fraksi daun rambutan (Nephelium lappaceum L) terhadap pertumbuhan bakteri Escherichia coli ATCC 25922 fraksi n-heksan konsentrasi tertinggi 40% replikasi III yaitu 9,4, fraksi etil asetat konsentrasi tertinggi konsentrasi 40% replikasi III yaitu 14,3 dan fraksi air konsentrasi tinggi 40% replikasi II yaitu 17,0. Konsentrasi hambat minimum (KBM) dari fraksi air daun rambutan (Nephelium lappaceum L) terhadap pertumbuhan bakteri Escherichia coli ATCC 25922 pada konsentrasi 1,25%.
Kata Kunci: Escherichia coli ATCC 25922, Nephelium lappaceum L, Difusi, Dilusi
Sistem Informasi Pengelolaan Barang Berbasis Web
Authors: Safitri Nadya , Ishak Andre Reynaldi 
Published: June 2023

Abstrak: Pengelolaan persediaan barang merupakan salah satu proses bisnis yang dikelola oleh perusahaan. Penelitian ini mengamati sebuah perusahan yang memiliki keterbatasan pemanfaatan teknologi dalam pengelolaan persediaan barang sehingga terjadi beberapa masalah diantaranya ketidaksesuaian pengeluaran, ketidak akuratan data yang dihasilkan, dan kesalahan dari pengelola yang menyebabkan kerugian pada perusahaan. Berdasarkan permasalahan tersebut penelitian ini melakukan pengembangan sistem informasi pengelolaan persediaan barang berbasis website. Pengembangan dilakukan dengan menggunakan metode Rapid Application Develompment, untuk model perancangan menggunakan Unified Modeling Language serta dilanjukan dengan pengkodingan berbasis website. Setelah aplikasi selesai pengujian dilakukan guna memastikan tidak ada bug dan penyamaan persepsi dengan pengguna dengan menggunakan pengujian Alpha dan Beta. Hasil dari penelitian ini diharapkan dapat mempermudah serta memberikan informasi yang lebih akurat dibanding sistem yang sedang berjalan.
Kata kunci: persediaan barang, rapid application development, unified modeling language, website