bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preparation, characterization, and stability of lipid nanoparticles including unsaturated lipids
Authors: Park Yeseul , Park Jin-Won 
Published: September 2023

Abstract
Among the SARS-CoV-2 vaccines developed to date, the mRNA vaccines developed by the Pfizer/BioNTech and Moderna companies have been formulated using saturated lipids, specifically 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC), along with cholesterol. DSPC and cholesterol have the disadvantage of causing sclerosis. Therefore, in this study, lipid nanoparticles (LNPs) were prepared and characterized by replacing DSPC with 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and excluding cholesterol. The results showed that the DOPC-based LNPs had a smaller diameter (75.67 nm) compared to the previous study and the polydispersity index (PI) indicated a good dispersion homogeneity, suggesting size uniformity. Additionally, the LNPs maintained their size between 57 nm and 152 nm and showed stable PI values (0.330–0.393) throughout the 25 days.
A zinc coordination compound showing green photoluminescence
Authors: Zhu Yu-Shu , Deng Cui-Er , Zhang Xue-Chun , Huang Kun-Lin , Liu Xi 
Published: September 2023

Abstract
A novel three-dimensional coordination compound has been solvothermally synthesized based on a tetracarboxylate ligand H4L (H4L = 1,3,6,8-tetrakis(4-carboxylphenyl)pyrene), Zn2L(H2O)2·2DEF (1) (DEF = N,N′-diethylformamide). Each Zn ion is coordinated by four carboxylate oxygen atoms from four L4− ligands and one oxygen atom from a water molecule to provide a distorted square-pyramidal geometry. Pairs of adjacent Zn cations are bridged by four carboxylate groups of four different L4− ligands to generate a paddle-wheel [Zn2(COO)4(H2O)2] secondary building unit (SBU). Each SUB is further linked to four L4− ligands to give a three-dimensional framework with cds-type (CdSO4-type) topology. The crystal structure has been determined via single-crystal X-ray diffraction, and the compound was characterized by elemental and thermal analysis, infrared spectroscopy, powder X-ray diffraction, and solid-state photoluminescence measurements.
Towards sustainable water purification: MOFs as a promising solution to eliminate toxic water pollutant resorcinol
Authors: Ahmad Khalil , Naseem Khalida , Shah Habib-ur-Rehman , Riaz Nagina Naveed , Alhadhrami A. , Majeed Hammad , Ahmad Muhammad Mahboob , Afzal Awan Muhammad Mateen , Ahmad Shakeel , Ashfaq Muhammad , Taj Muhammad Babar , Abd Elsalam Hassan E. 
Published: September 2023

Abstract
Water pollutants especially alcoholic based aromatic compounds are documented as emergent water pollutants and caused serious health problems for all living organisms. It is a major challenge for all researchers to synthesize effective adsorbents to eliminate these water pollutants. For this purpose, two MOFs were synthesized and characterized using SEM, FTIR, EDX and PXRD techniques. These MOFs exhibited excellent adsorption capacity for resorcinol and adsorption process was spontaneous, endothermic and proceeds with physiosorption as confirmed using thermodynamics data (∆H
ads = 30.473 kJ/mol). Furthermore, separation-factor value was in the range of 0.0238–0.1312 for 30–100 ppm resorcinol concentration which represents that adsorption process was favorable. Langmuir and Pseudo 2nd order Models were best described which represented that chemisorption process also favored due to presence of –OH group and N-atom between adsorbent and adsorbate as well as monolayer adsorption-process is proceeded. Moreover, ion-exchange and electrostatic-interactions are the major interactions which are responsible for adsorption of resorcinol. Along with electrostatic-interactions, ion-exchange, hydrogen-bonding and π–π stacking/interactions are also accountable for adsorptive elimination of resorcinol. In summary we can conclude that MOFs are considered outstanding adsorbents for elimination of water pollutants to purify water, as water is very important for healthy life.
Features of the management of the rule of Urbakh in ZnSe:Yb crystals
Authors: Kinzerska O.V. , Senko I.M. , Slyotov M.M. , Slyotov O.M. , Mazur T.M. 
Published: September 2023

A comparative analysis of the edge absorption spectra measured in the temperature range of 290–470 K for two types of zinc selenide substrates has been carried out. It has been established that the self-absorption edge of pure ZnSe: Yb melt crystals is described by the «crystalline» approximation of the general Urbach rule, which is a consequence of dynamic disordering. In samples doped with ytterbium, at 330 K, a reversible transition from dynamic to static disordering was detected, which is described by the “glassy” approximation of the general Urbach rule.
Toward ultraflexible organic electronic devices
Authors: Park Sungjun , Takakuwa Masahito , Fukuda Kenjiro , Lee Sunghoon , Yokota Tomoyuki , Someya Takao 
Published: September 2023

AbstractIn recent decades, organic electronics have progressed remarkably, owing to their exceptional mechanical and electrical properties. The development of ultraflexible organic electronics has opened up possibilities for applications such as wearable electronics, flexible displays, and skin- and tissue-compatible sensors with good breathability. In this article, we introduce state-of-the-art ultrathin and high-performance functional organic electronic devices and their integration with potential applications. Our focus is on the strategies for advancing new materials, novel device structures, and diverse applications, which have enabled the development of multifunctional and complex systems. Additionally, we highlight the challenges and opportunities for future research in this field, including improving stability and reliability over long periods, ensuring scalability and cost-effectiveness of production, and addressing issues related to integration into larger systems. Finally, we present future directions in this exciting and rapidly growing field of ultraflexible organic electronics.Graphical abstract
An orthotropic damage model for masonry walls with consistent damage evolution laws
Authors: Teschemacher Tobias , Kalkbrenner Philip , Pelà Luca , Wüchner Roland , Bletzinger Kai-Uwe 
Published: September 2023

AbstractThis research presents a constitutive model for the macro scale simulation of masonry structures. The model is containing an orthotropic plane stress assumption, which appears as an appropriate assumption for the in-plane analysis of masonry walls. The material model is based upon damage mechanics, split into tensile and compression parts. The novelty herewith is the consistent mapping of the damage evolution laws. Aim of this research is to develop a simple but accurate constitutive law, suitable to simulate large scale structures and buildings with reasonable computational costs. The developments are presented and compared with available literature examples from laboratory testings.
Realization of malignant potential of human glioblastoma mitochondria in immunodeficient animals
Authors: Kit O. I. , Frantsiyants E. M. , Shikhlyarova A. I. , Neskubina I. V. 
Published: September 2023

Purpose. Obtaining extracranial diﬀuse tumor foci of glioblastoma in Balb/c Nude mice by implantation of mitochondria isolated from human glioblastoma.Material and methods. Human glioblastoma mitochondria were isolated using diﬀerential centrifugation in a high speed refrigerated centrifuge. Mitochondrial samples were diluted with 0.9 % NaCl solution to a protein concentration of 3 mg of protein in 0.4 ml of saline. Balb/c Nude mice (N = 6) were intraperitoneally transplanted with freshly isolated glioblastoma mitochondria at the rate of 3 mg of protein per 1 animal in 0.4 ml of physiological solution. Male mice of Balb/c Nude line (N = 4), which were injected once intraperitoneally with 0.4 ml of physiological solution, served as control. All animals were euthanized by guillotine decapitation 17-21 days aﬅer parenteral implantation of mitochondria isolated from glioblastoma.Results. Speciﬁc changes in the spleen structure were revealed (N = 4): the formation of strands of cells resembling glioblastoma multi-forme was observed in multiple ﬁelds of vision. The initiation of diﬀuse growth of glioblastoma cells in the stromal part of the red pulp of the spleen was evidenced by the expression of GFAP and ki-67, which were also recorded in the tumor preparation of the patient with glioblastoma. Morphological examination of the mesentery and lymph nodes revealed multiple areas with atypical cells resembling glioblastoma multiforme, localized in ﬁbrous septa and sinuses. Stained granules with the corresponding immunohistochemical proﬁle, GFAP and ki-6, were clearly deﬁned in the mesentery and lymph node of a Balb/c Nude mouse (N = 6) aﬅer transplantation of human glioblastoma mitochondria. An additional study of the immunophenotype of cells in the spleen, mesentery, and lymph nodes of Balb/c Nude mice by the generally accepted marker S100 leﬅ no doubt about the induction of malignant growth aﬅer transplantation of mitochondria isolated from human glioblastoma.Conclusions. Parenteral implantation of mitochondria isolated from human glioblastoma in male Balb/c Nude mice Might cause the growth and development of extracranial foci of glioblastoma in animals.
Radiomics of magnetic resonance imaging for assessment of pathological complete response to neoadjuvant therapy and long-term survival in breast cancer
Authors: Petrova N. V. , Karmazanovsky G. G. , Kondratyev E. V. , Popov A. Yu. , Rostovtsev M. V. , Germanovich N. Yu. , Kalinin D. V. 
Published: September 2023

Breast cancer (BC) is the most common malignant disease. The use of neoadjuvant drug therapy increases the likelihood of achieving a complete pathomorphological response (pCR), leads to an increase in resectability and ablation; helps to determine the sensitivity of tumor cells to chemopreventive agents, thereby improving the patient’s prognosis. Since pathomorphological assessment occurs aﬅer surgery, it is necessary to develop methods for non-invasive response assessment for timely correction of the volume of treatment. One such method is magnetic resonance imaging (MRI). Assessment of the obtained images using texture analysis allows to increase the accuracy of the method both in the control of neoadjuvant treatment and in the assessment of the response to neoadjuvant therapy during preoperative planning.This article provides an analysis of the literature data on the potential to improve the prognostic value of breast MRI in assessing the complete pathomorphological response to neoadjuvant drug treatment of breast cancer using texture analysis of data.
Impact of the type of anesthesia on the frequency of postoperative complications after hernioplasty and on the dynamics of the frailty index in elderly patients with inguinal hernia
Authors: Akhverdiev B. D. 
Published: September 2023

Purpose of the study. The purpose of the study was to compare the eﬀect of spinal and general anesthesia on the incidence of postoperative complications aﬅer hernioplasty and on the dynamics of the frailty index (FI) in elderly patients with inguinal hernia.Patients and methods. 78 patients diagnosed with inguinal hernia were involved in the study (average age was 70.1 ± 0.8 years). Patients underwent open hernia repair and Lichtenstein plasty of the posterior wall of the inguinal canal. The patients were divided into two groups depending on the type of anesthesia: spinal anesthesia (SA; N = 65) and general anesthesia (GA; N = 13). At the time of admission, 30 days aﬅer the surgery, the FI was calculated using the Edmonton questionnaire.Results. In the SA group, 39 patients (60 %) had a FI ≥ 7; 9 patients (13.8 %) had a FI ≥ 9; 8 patients (12.3 %) had a FI ≥ 11; and 9 patients (13.8 %) had the highest FI ≥ 12. At 30 days aﬅer surgery, 20 patients (30.8 %) showed a decrease in FI values (FI from 7 to 9 decreased almost 2-fold). In the GA group, on the day of admission, 6 patients (46.2 %) had FI ≥ 7, 5 (38.5 %) had FI ≥ 9, and 2 (15.4 %) had FI ≥ 11. At 30 days aﬅer surgery, no changes were observed in patients with FI ≥ 7.Conclusion. In the spinal anesthesia group, urinary retention was predominant among complications, while in patients aﬅer general anesthesia, pulmonary atelectasis prevailed among complications. The use of spinal anesthesia for hernioplasty was accompanied by a decrease in the frailty index within 30 days aﬅer surgery in individuals with a FI ≥ 7. In the GA group, decrease in the index within 30 days aﬅer surgery was observed in patients with FI ≥ 9.
The role of the infectious factor in the genesis of perinatal losses in pregnant women who have birth in maternity hospitals in St. Petersburg and Leningrad Region in 2009–2018
Authors: Bezhenar Vitaly F. , Ivanova Lidiia A. , Ivanov Dmitry O. 
Published: September 2023

BACKGROUND: One of the tasks of modern medicine is to reduce the level of perinatal losses, for which it is necessary to know their main causes.
AIM: To determine the course of an infectious disease in the genesis of perinatal losses.
MATERIALS AND METHODS: In order to determine the role of infection in the genesis of perinatal losses, a retrospective study was conducted with two groups: the main group 307 women with perinatal fetal death, the control group 357 women without perinatal losses. An analysis was also made of the data of the statistical form No. 32 (annual) Information on medical care for pregnant women, women in childbirth and puerperas, presented by the Medical Information and Analytical Centers of St. Petersburg and the Leningrad Region for 20062018 and annual reports of the Leningrad Regional Pathological Anatomical Bureau for 20062016.
RESULTS: In 20062018, the leading causes of perinatal death were intrauterine hypoxia and asphyxia during childbirth (ICD 10: P20, P21), that is, not diseases, but symptomatic conditions. Such features of reporting documentation complicate the analysis of the causes of perinatal losses and the implementation of a set of preventive measures, including at the state level. Also, according to the official report, it is impossible to assess the contribution of a specific virus and a specific localization of the lesion to the genesis of perinatal losses. In the main group, hematogenous viral and ascending bacterial infection of the placenta was detected 4 times more often. With a combination of bacterial and viral infection of the placenta, the risk of a fatal outcome increases. Infectious pathogens most frequently encountered in perinatal losses have been established.
CONCLUSIONS: The cause of more than half of the cases of perinatal losses in women who gave birth in maternity hospitals in St. Petersburg and Leningrad Region in 20092018 is an infectious pathology: viral, bacterial and viral-bacterial, and not intrauterine hypoxia/asphyxia during childbirth, as stated by the official statistics. In this regard, the main direction in the prevention of perinatal losses is the timely detection and treatment of infectious pathology.
Newborn asphyxia: features of the course of pregnancy and delivery and the structure of the placenta
Authors: Ivanova Lidiia A. , Ivanov Dmitry O. , Bezhenar Vitaly F. , Krasnogorskaya Olga L. 
Published: September 2023

BACKGROUND: The main cause of early neonatal death is neonatal asphyxia. Asphyxia transferred during childbirth can lead to damage of the brain, respiratory disorders, hemodynamic disorders, and impaired renal function.
AIM: The aim of the study is to determine the factors predisposing to the birth of a child in a state of asphyxia.
MATERIALS AND METHODS: A retrospective study was conducted, which included the analysis of medical records of 11,662 women who gave birth at the Perinatal Center of the Saint Petersburg State Pediatric Medical University (level IIIB obstetric institution), whose pregnancy ended in urgent delivery. The main group included patients who gave birth to full-term babies in a state of moderate and severe asphyxia (n = 70), the control group included patients who gave birth to children without asphyxia (n = 11,592).
RESULTS: Factors predisposing to the birth of a full-term baby in a state of moderate and severe asphyxia were identified, which can be used to develop a system for predicting the birth of a child in a state of asphyxia and a set of preventive measures.
CONCLUSIONS: More frequent ascending infection of stage II and III makes it necessary to timely identify and treat a bacterial infection in all full-term pregnant women. A prognostic model for the birth of a full-term baby in a state of asphyxia has been constructed. Women at risk should undergo an additional examination at 37 weeks of pregnancy: sowing from the cervical canal for flora and sensitivity to antibacterial drugs to identify pathogenic and opportunistic microflora, childbirth should be carried out under mandatory constant monitoring control.
Desenvolvimento de um vídeo educacional como recurso de ensino em projetos de produtos para área da Saúde
Authors: Alves Júlio Cesar da Rocha , Falcão Luiz Fabio Magno , Normando Valéria Marques Ferreira 
Published: September 2023

Introdução: O fortalecimento do Sistema Único de Saúde requer das instituições de ensino e pesquisa a proposição de ideias inovadoras em processos e produtos. Objetivo: O objetivo do estudo foi desenvolver e validar uma mídia audiovisual como recurso de ensino na criação de projetos tecnológicos para área da saúde. Metodologia: Trata-se de um estudo de desenvolvimento de tecnologia educacional, abrangendo etapas de estudos pré-produção, produção e validação. Ocorreu no âmbito do curso de Fisioterapia da Universidade do Estado do Pará e contou como participantes da pesquisa com estudantes do 3º e 4º ano do curso de Fisioterapia e com profissionais da área de ensino em saúde, atuando como juízes especialistas. Resultados: Como resultados do estudo de revisão foram definidos conceitos, atributos e etapas de projeto de produtos. O estudo exploratório-descritivo demonstrou necessidade de aprimoramento nas competências relacionadas à concepção criativa de projetos e formas de representação. Conclusão: Os resultados dos estudos iniciais embasaram a composição do roteiro e a produção do vídeo educacional. No processo de validação de conteúdo e validação semântica do vídeo educacional, obtiveram-se Índice de Validação de Conteúdo de 86% e Índice de Validação de Semântica de 97%, sendo considerado válido e adequado ao uso como recurso de ensino na criação de projetos de produtos em saúde.
A betűtípus és a szövegértés összefüggésének vizsgálata felső tagozatos tanulók körében
Authors: Gombos Péter , Látics Barbara 
Published: September 2023

A kutatás alapvető kérdése, hogy mekkora szerepe van a betűtípus megválasztásának egy szöveg megértésében, illetve felidézésében felső tagozatos tanulók körében. A vizsgálat hipotézise szerint a felső tagozatos tanulók szövegértésére, az információk felidézésére kedvezőbb hatással van a talpas betűtípussal írt szöveg, mint a talpatlan. A szakirodalomban nincs egységes álláspont ebben a kérdésben. Korábban főleg a betűtípusok képernyőről történő olvashatóságát mérték, jellemzően felnőttek körében. A kutatás egy talpas (Cambria) és egy talpatlan (Candara) betűtípusú szövegértési tesztet alkalmazott. Összesen 450 felső tagozatos tanuló vett részt a felmérésben, amelyben a szöveg olvasását egy szövegértési teszt követte, majd két héttel később 5-5 kérdésből álló felidézéses tesztet töltött ki 196 tanuló. A teszt célja annak felmérése volt, hogy a talpas vagy a talpatlan szöveg esetében eredményesebb-e az információk előhívása. Kétmintás, párosított t-próbát alkalmazva történt a szövegértési, valamint felidézéses tesztek eredményeinek az összehasonlítása. Szignifikáns különbség nem mutatkozott az eredmények között. A hipotézisek nem igazolódtak: felső tagozatos tanulók esetében sem a szövegértésre, sem az információk felidézésére nincs kedvezőbb hatással a talpas betűtípussal írt szöveg.
The effect of urbanization and behavioral factors on coyote net displacement and its implications for seed dispersal
Authors: Gelmi-Candusso Tiziana A. , Wheeldon Tyler J. , Patterson Brent R. , Fortin Marie-Josée 
Published: September 2023

Abstract
Coyotes (Canis latrans) may be important seed dispersal vectors in urban areas, given their omnivorous diet and wide-ranging movement patterns potentially able to bypass fragmentation. However, fragmentation itself, anthropogenic food sources, and human activity can limit their natural movement patterns. Previous research has found urbanization limits movement range across mammals; however, it remains unclear the degree to which this may cascade into seed dispersal as seed retention time plays an important role in seed dispersal distance. Additionally, social and temporal changes in behavior influence coyote movement patterns, likely interacting with the effect of urbanization on net displacement and seed dispersal. We used GPS telemetry data to analyze the effect of urbanization on coyote net displacement (n = 94 individuals), in interaction with social and temporal factors, for a series of seed retention timeframes. We found that urbanization led to shorter net displacement in comparison to rural areas. The effect of urbanization increased with increasing seed retention timeframe and disproportionately affected long-distance seed dispersal. While seasonality did not influence the effect of urbanization, social status had a strong interaction effect, whereby the effect of urbanization was strong for transient and dispersing coyotes but negligible for resident coyotes, as territoriality was likely the main limiting factor for the latter, whereas the former, which were wider ranging, were most affected by the urban matrix. Interestingly, despite the urban effect, coyote net displacement varied across social statuses and seasons in both landscape types, suggesting coyotes can provide a heterogenous seed dispersal contribution within and across plant species. Future research on fine-scale movement patterns and scat analysis is needed to better understand the cascading effects of decreased long-distance net displacements on urban plant populations.
First report of Fusarium anthophilum causing drying on Butia odorata in Rio Grande do Sul, Brazil
Authors: Arellano Alfonso Daniel Victoria , Chaves Fabio , Marquez-Licona Guillermo , Solano-Báez Alma Rosa , Martinez Francisco Javier Camacho , Dallagnol Leandro J. 
Published: September 2023

Abstract
Butia spp. is a palm tree native to southern Brazil and Uruguay. The fruits are consumed fresh and used to make many food products, while the leaves are commonly used to make crafts. In January 2018, severe symptoms of wilt and drying were identified in clusters of Butia odorata occurring on the leaf and the rachis (in a proportion of 50% of leaf area). The pathogen was isolated from a stump extracted from a symptomatic tree. The morphologic characters showed a presence of macroconidia and microconidia with a classic salmon color of some species of the Fusarium genus. The molecular identification of the locus of actin (ACT), calmodulin (CAL), factor elongation 1-alpha (TEF1) and histone (HIS3), confirmed the identity of Fusarium anthophilum. This finding will help growers and agronomists prevent and manage this disease. To the best of our knowledge, this is the first report of Fusarium antophilum causing disease in Butia odorata.