bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Motivasi dan Kemandirian Belajar Terhadap Prestasi Akademik Mahasiswa
Authors: Cahyadiana Windarini , Anita Anita 
Published: August 2023

Abstrak. Tujuan penelitian ini untuk mengetahui apakah motivasi dan kemandirian belajar memiliki pengaruh signifikan terhadap prestasi akademik mahasiswa, baik pengaruh secara parsial maupun secara simultan. Penelitian dilakukan dengan menggunakan responden mahasiswa STIKI Malang. Data yang diolah, merupakan data yang diperoleh melalui pengisian angket yang dilakukan secara online kepada mahasiswa STIKI Malang, serta melalui pengamatan terhadap mahasiswa STIKI Malang selama proses pembelajaran. Dari data yang diperoleh, kemudian diolah dan diuji dengan menggunakan uji validitas, uji reliabilitas, uji signifikansi, dan uji asumsi klasik, serta uji heteroskedastisitas. Dari hasil penelitian diketahui, secara simultan, motivasi dan kemandirian belajar berpengaruh signifikan terhadap pencapaian prestasi akademik mahasiswa.
Abstract. The purpose of this research is to determine wether motivation and learning independence have a significant effect on student academic achievement, either partially or simultaneously. The research was conducted using STIKI Malang student respondent. Processed data is obtained through filling out online questionnaires to STIKI Malang students, as well as through observations of STIKI Malang students during the learning prosess. Then the data obtained, processed and tested using the validity, reliability, significance, classical assumption test, and heteroscedasticity test. From the research result it is known that simultaneously, learning motivation and learning independence have a siginificant effect on student academic achievement.
Efikasi Diri Dengan Prokrastinasi Pada Karyawan Taman Wisata Air Wendit Kabupaten Malang
Authors: Handayani Sri Wiworo Retno Indah , Lindayani Ni Luh , Anisa Nurfa 
Published: August 2023

Abstrak. Tujuan dari penelitian ini untuk mengetahui hubungan efikasi diri dengan prokrastinasi pada karyawan Taman Wisata Air Wendit. Penelitian ini menggunakan metode penelitian kuantitatif dengan populasi dan sampel berjumlah 40 karyawan. Untuk mengetahui hubungan efikasi diri dengan prokrastinasi karyawan, maka digunakan rumus korelasi product moment. Penghitungan reliabilitas item skala menggunakan SPSS 24.0, hasil uji korelasi dengan formula Pearson Product Moment menunjukan terdapat hubungan negatif sangat signifikan antara efikasi diri dengan prokrastinasi yang terlihat dari nilai r sebesar -.690 dengan taraf signifikansi 0.000 lebih kecil dari phi 0.01. Dengan demikian hipotesis diterima, sehingga ada hubungan efikasi diri dengan prokrastinasi karyawan Taman Wisata Air Wendit Kabupaten Malang. Artinya bahwa semakin tinggi efikasi diri partisipan maka prokrastinasi akan menurun, dan begitu pula sebaliknya. Hasil penelitian menyatakan bahwa ada hubungan antara efikasi diri dengan prokrastinasi karyawan Taman Wisata Air Wendit. Prokrastinasi kerja subjek dalam penelitan ini tergolong tinggi dan efikasi diri subjek tergolong rendah dengan sumbangan variabel efikasi diri terhadap prokrastinasi sebesar 47%, sehingga masih ada kemungkinan sebesar 53% faktor lain mempengaruhi prokrastinasi kerja antara lain motivasi kerja, stress kerja, beban kerja dan kontrol diri.
Abstract: The purpose of this study was to determine the relationship between self-efficacy and procrastination among Wendit Air Tourism Park employees. This study uses quantitative research methods with a population and sample of 40 employees. To find out the relationship between self-efficacy and employee procrastination, the product moment correlation formula is used. Calculation of the reliability of scale items using SPSS 24.0, the results of the correlation test with the Pearson Product Moment formula showed that there was a very significant negative relationship between self-efficacy and procrastination as seen from the r value of -.690 with a significance level of 0.000, less than phi 0.01. Thus the hypothesis is accepted, so that there is a relationship between self-efficacy and procrastination by employees of the Wendit Water Tourism Park, Malang Regency. This means that the higher the participant's self-efficacy, the procrastination will decrease, and vice versa. The results of the study stated that there was a relationship between self-efficacy and procrastination of Air Wendit Tourism Park employees. The subject's work procrastination in this study is high and the subject's self-efficacy is low with the contribution of the self-efficacy variable to procrastination by 47%, so there is still a 53% possibility that other factors affect work procrastination including work motivation, work stress, workload and self-control .
Hypolipidemic Activity of Sesquiterpene Lactones and their Derivatives
Authors: Adekenov Sergazy , Mareška Václav , Ivanov Vladimir , Maslova O. V. , Doskaliyev Aidos , Shaidarov M. Z. , Spiwok Vojtech 
Published: August 2023

BACKGROUND: Despite the available range of lipid-lowering drugs, mainly of synthetic origin, the problem of atherosclerosis therapy and its manifestations remain unresolved. Bioinformatics methods, in particular molecular docking, are considered as a promising direction in terms of developing effective original lipid-lowering drugs. Today, as a promising source of natural lipid-lowering agents, it is advisable to consider natural terpenoids, namely sesquiterpene lactones, which are distinguished by a wide range of pharmacological activity. This article presents the results of a virtual and biological screening of the lipid-lowering activity of sesquiterpene γ-lactones and their chemically modified derivatives.
AIM: The aim is to evaluate the lipid-lowering properties of samples of sesquiterpene γ-lactones and their derivatives by virtual and biological screening methods.
METHODS: Molecular modeling of the binding energy of the “ligand-target” complex (docking). Molecular docking of the lipid-lowering activity of sesquiterpene γ-lactones and their derivatives was performed using the Glide program from the developer of the Schrodinger Small-Molecule Drug Discovery package using the Extra Precision algorithm (https://www.schrodinger.com/glide). The effect of sesquiterpene lactones on the expression of genes for key enzymes of lipid metabolism in the liver was studied in an in vivo model of hyperlipidemia caused by an atherogenic diet.
CONCLUSION: Virtual screening of the lipid-lowering activity of sesquiterpene γ-lactones and their derivatives by molecular docking revealed a number of promising compounds (matricin, matricarin, grossmisin oxime, austricin oxime, 5β (H)-austricin) receptor interactions on the enzyme system cholesterol 7α-hydroxylase (CYP7A1). New mechanisms of lipid-lowering activity for sesquiterpene γ-lactones were proposed, which were established in the study of gene expression of key enzymes of lipid metabolism in the liver in a model of hyperlipidemia caused by an atherogenic diet in rats under in vivo conditions.
Depression Symptom Patterns as Predictors of Metabolic Syndrome and Cardiac Events in Symptomatic Women with Suspected Myocardial Ischemia: The Women's Ischemia Syndrome Evaluation (WISE and WISE-CVD) Projects
Authors: Virzi Nicole E. , Krantz David S. , Bittner Vera A. , Bairey Merz C Noel , Reis Steven E. , Handberg Eileen M. , Pepine Carl J. , Vaccarino Viola , Rutledge Thomas 
Published: August 2023

Background:
Ischemic heart disease (IHD) risk in women includes biomedical, behavioral, and psychosocial contributors. The purpose of this study was to build upon previous research suggesting that in women, somatic symptoms (SS) of depression may be important to the development of IHD risk factors and major adverse cardiovascular events (MACE). Based on previous findings, we hypothesized that: (1) SS would be associated with robust biomedical predictors of heart disease and functional capacity, while cognitive symptoms (CS) of depression would not, and (2) SS would independently predict adverse health outcomes while CS would not.

Methods:
We examined the relationships between symptoms of depression (SS/CS), metabolic syndrome (MetS), inflammatory markers (IM), coronary artery disease (CAD) severity, and functional capacity in two independent cohorts of women with suspected IHD. In the Women's Ischemia Syndrome Evaluation (WISE), we also examined these variables as predictors of all-cause mortality (ACM) + MACE over a median 9.3-year follow-up. The WISE sample included 641 women with suspected ischemia with or without obstructive CAD. The WISE-Coronary Vascular Dysfunction (WISE-CVD) sample consisted of 359 women with suspected ischemia and no obstructive CAD. All study measures were collected uniformly at baseline. Depressive symptoms were measured via the Beck Depression Inventory. MetS was assessed according to Adult Treatment Panel III (ATP-III) criteria.

Results:
In both studies, SS was associated with MetS (Cohen's d = 0.18, 0.26, P < 0.05, respectively), while CS was not. Within WISE, using Cox Proportional Hazard Regression, SS (Hazard ratio [HR] = 1.08, 95% confidence interval [CI] = 1.01–1.15; HR = 1.07, 95% CI = 1.00–1.13) and MetS (HR = 1.89, 95% CI = 1.16–3.08; HR = 1.74, 95% CI=1.07–2.84) were independent predictors of ACM + MACE after controlling for demographics, IM, and CAD severity, while CS was not.

Conclusions:
In two independent samples of women undergoing coronary angiography due to suspected ischemia, SS but not CS of depression were associated with MetS, and both SS and MetS independently predicted ACM and MACE. These results add to previous studies suggesting that SS of depression may warrant specific attention in women with elevated cardiovascular disease (CVD) risk. Future research evaluating the biobehavioral basis of the relationship between depression, MetS, and CVD is needed.
Perceived Stress and Cardiovascular Disease in a Community-Based Population
Authors: Zhang Yasi , Zhang Aijie , Xiang Jianbang , Zhan Yiqiang 
Published: August 2023

Background:
Perceived stress plays an important role in the pathogenesis of cardiovascular diseases (CVDs). Their associations with CVDs in the Chinese population are less investigated. The present study aims to investigate the associations of perceived stress with well-defined CVDs in a population-based survey in Shenzhen, China.

Methods:
In the community-based survey, we recruited 2,287 participants aged 18 years and over from 8 communities in Shenzhen, China. Perceived stress was assessed using the modified Chinese version of the Perceived Stress Scale with 14 items and a five-point Likert scale. CVDs including coronary heart disease, heart failure, and atrial fibrillation were ascertained from electronic health records and confirmed by family physicians. Potential confounders included age, sex, educational attainment, occupation, smoking, and alcohol-drinking habits. Multivariable logistic regression models were employed to estimate the magnitude of the associations.

Results:
Overall, the average perceived stress score was 37.2 (standard error: 7.2 and range: 14–70) among the participants. The prevalence of CVDs was 2.7%. After controlling for age, sex, educational attainment, occupation, smoking, and alcohol-drinking habits, a higher perceived stress score was significantly associated with higher risks of CVDs (odds ratio [OR]: 1.25, 95% confidence interval [CI]: 1.01–1.55). The associations were comparable among men (OR: 1.20, 95% CI: 1.01–1.43) and women (OR: 1.29, 95% CI: 1.02–1.63). We also examined the potential nonlinear relationship using restricted cubic spines and found that the relationship was almost linear.

Conclusions:
Our analysis showed that higher perceived stress was associated with higher risks of CVDs among adults. Future studies are warranted to clarify the biological mechanisms and shed light on these associations.
Short-Term Outcomes and Their Predictors among Patients with Cardiorenal Syndrome Hospitalized for Heart Failure
Authors: Shehu Muhammad N. , Okeahialam Basil N. , Borodo Musa M. , Sani Mahmoud U. , Isezuo Simeon A. 
Published: August 2023

Context:
Cardiorenal syndrome (CRS) encompasses a spectrum of disorders involving both the heart and kidneys in which acute or chronic dysfunction in one organ may induce acute or chronic dysfunction in the other organ.

Aim:
To review the short-term outcomes and their predictors among patients admitted with HF complicated by renal impairment.

Settings and Design:
This was a cross-sectional study conducted at the Aminu Kano Teaching Hospital, Kano, Nigeria.

Materials and Methods:
Patients aged 18 years and above were consecutively recruited over a period of 11 months. Detailed history and physical examination as well as relevant baseline blood chemistry, full blood count, urinalysis, estimated glomerular filtration rate, ECG, echocardiography, and renal ultrasound were carried out on all patients.

Statistical analysis used:
The data was analyzed using SPSS Version 16.0. Student t-test and the nonparametric χ2 or Fisher's exact test were used to test for significance among the noncategorical and categorical variables, respectively.

Results:
One hundred and twenty four (72.9%) patients had CRS. Patients with CRS had a significantly higher mortality rate compared with those without the syndrome (25% vs. 13%; P = 0.031). There was no significant difference in the duration of hospital stay between patients with CRS and those without CRS (17.86 ± 13.11 vs. 15.85 ± 13.46; P = 0.378). Serum creatinine of ≥170 μmol/L and serum urea of >20 mmol/L were the identified predictors of mortality (95% confidence interval [CI] 1.098–6.243, RR = 2.618, P = 0.030; and 95% CI 1.106–6.757, RR = 2.734, P = 0.029, respectively).

Conclusion:
CRS is associated with a significantly higher mortality rate. Measures of the renal function, serum creatinine >170 μmol/L and serum urea of >20 mmol/L were identified as the predictors of mortality.
Predictors of Vaginal Delivery Following Stimulation of Uterine Contractions for Term Premature Rupture of Membranes
Authors: Okoror Collins Ejakhianghe Maximilian , Ezeanochie Michael Chudi , Ande Adedapo Babatunde Anibaba 
Published: August 2023

Context:
Premature rupture of membranes (PROM) is a significant event as it may lead to maternal complications, increased operative procedure, neonatal morbidity, and mortality.

Aim:
To determine the predictors of successful vaginal delivery in pregnant women undergoing stimulation of uterine contractions following premature rupture of membranes (PROM).

Settings and Design:
This prospective cohort study was conducted at the University of Benin Teaching Hospital, Benin City, Nigeria.

Materials and Methods:
Seventy-four pregnant women between the gestational ages of 37 weeks and 41 weeks with a live singleton fetus in cephalic presentation and no contraindication to vaginal delivery who had stimulation of uterine contractions following term PROM were included in this study. The main outcome measure was the route of delivery.

Statistical Analysis:
The analysis was done with IBM statistical package for social science (SPSS) Statistics v21, and a P value ≤0.05 was considered statistically significant.

Results:
Sixty-two (83.8%) women had a vaginal delivery. The mean age and gestational age were 29.76 ± 3.69 years and 39.04 ± 1.15 weeks, respectively. The chance of vaginal delivery was increased with BMI <30 (RR = 9.091, 95% CI = 1.827–45.246). The duration between rupture of membranes and commencement of stimulation of uterine contractions was ≤8 h (RR = 4.889, 95% CI = 1.307–18.293) also increasing the chance of achieving vaginal delivery. The time interval to 4 cm cervical dilatation ≤4 h (RR = 4.167, 95% CI = 1.141–15.215) and time interval to delivery ≤8 h (RR = 12.222, 95% CI = 2.433–61.402) also favored vaginal delivery.

Conclusion:
When uterine contractions are stimulated for PROM at term, vaginal delivery is predicted by maternal BMI <30, duration of rupture of membrane ≤ 8 h, and time interval to 4 cm cervical dilatation ≤4 h. Also, it was found was that vaginal delivery becomes less likely when the time interval from stimulation to delivery exceeds 8 h.
Functional Correlates of Malnutrition Among Older Patients in a Primary Care Clinic in Northern, Nigeria
Authors: Olawumi Abdulgafar Lekan , Grema Bukar Alhaji , Suleiman Abdullahi Kabir , Omeiza Yakubu Sule , Michael Godpower Chinedu 
Published: August 2023

Context:
Nutritional and functional impairments are assumed to be inevitable consequences of aging and they attract little attention in the primary care setting.

Aim:
To determine the association between malnutrition and functional status of the elderly to advocate for their routine screening in the primary care clinics and similar settings.

Settings and Design:
A cross-sectional descriptive study involving 352 patients of age ≥60 years who presented at the Family Medicine Clinic.

Methods and Materials:
The nutritional status was assessed using the Mini Nutritional Assessment tool, whereas functional capacity was assessed using Katz and Lawton index for the Activities of Daily Living (ADL) and Instrumental Activities of Daily Living (IADL), respectively.

Statistical Analysis:
Chi-square test and logistic regression analysis were used to determine associations between variables and nutritional status, and determinants of nutritional status, respectively.

Results:
The mean age of respondents was 67.9 ± 7.6 (60–95) years; 215 (61.1%) were women. The prevalence of malnutrition was 25.9% and of risk of malnutrition 53.1%. Advancing age (odds ratio [OR] = 4.93, 95% confidence interval [CI] =1.42–1.71, P ≤ 0.001), low monthly income (OR = 9.29, 95% CI = 0.20–43.50, P = 0.005) and being functionally dependent (OR = 14.706, 95% CI = 1.26–3.35, P = 0.03 for ADL; OR = 17.51, 95% CI = 5.07–37.31, P = 0.004 for IADL) were the determinants of malnutrition in the elderly patients.

Conclusion:
The prevalence of malnutrition and those of at-risk of malnutrition was high. Advancing age, low income, and functional dependence were the independent correlates.
Determinants of Personal Hygiene Practices
Authors: Ibrahim Usman M. , Jibo Abubakar M. , Gadanya Muktar A. , Musa Abubakar , Tsiga Ahmed Fatimah I. , Jalo Rabiu I. , Audu Sunday , Danzomo Abba A. , Abdullahi Shamsudden , Bashir Usman , Umar Muhammad L. 
Published: August 2023

Background:
Increasing consumption of vended foods may pose a significant public health threat associated with food-borne illnesses. Context: Increasing consumption of vended foods may pose a significant public health threat associated with food borne illnesses.

Aim:
To assess and compare the determinants of personal hygiene practices among street food vendors and canteen food handlers in a commercial city of northwestern Nigeria.

Settings and design:
Using interviewer-administered questionnaire, comparative cross-sectional design was used

Materials and Methods:
As much as 310 (in each group) street food vendors and canteen food handlers, selected using a multistage sampling technique.

Data analysis used:
The data was analyzed using SPSS Version 22.0

Results:
The proportion of street food vendors practicing correct personal hygiene measures were 214 (70.2%), compared with 213 (74.0%) canteen food handlers, respectively. There was a significant association between street food vendor's sex, ethnicity, educational status, hepatitis A or typhoid vaccination status, and the correct practice of personal hygiene (P < 0.05). Sex was found to be an independent predictor of personal hygiene practice (adjusted odds ratio = 4.7, 95% confidence interval = 1.3–16.7) among street food vendors with female street food vendors being five times more likely to observe correct personal hygiene practice than their male counterparts.

Conclusions:
Personal hygiene practice was found to be good among both street food vendors and canteen food handlers. However, there is a need for improvement if food-borne diseases are to be controlled; therefore, the government should ensure training and enforcement of all regulations to improve the personal hygiene practice thereby reducing the burden of food-borne illnesses.
Factors Associated with the Use of Outcome Measures among Physiotherapists Working in Neurorehabilitation Units in Tertiary Hospitals of North-Western Nigeria
Authors: Sani Fatima Sada , Ahmad Rufai Yusuf 
Published: August 2023

Context:
The use of standardised outcome measures (SOMs) is an essential part of rehabilitation and is widely endorsed as an excellent practice.

Aim:
The purpose of this descriptive study was to identify the factors associated with the use of OMs among physiotherapists working in neurorehabilitation units in tertiary hospitals of North-Western Nigeria.

Materials and Methods:
Physiotherapists managing neurological conditions in North-Western Nigeria were asked to complete a structured self-administered questionnaire that has two sections. Section I comprises items consisting of demographic information and Section II comprises items regarding the knowledge, attitude, use, perceived benefits and factors that hinder the use of SOMs among physiotherapists managing neurological conditions.

Results:
over 72.9% of the respondents were familiar with OMs; majority (77.1%) had poor attitude even though they had positive perception about the use of OMs. The respondents reported four most crucial factors hindering the use of OMs in neurological physiotherapy practice in tertiary hospitals in North-Western Nigeria, which are unavailability of appropriate tools, lengthy completion time of OMs, inadequate office space and lack of training on how to use OMs.

Conclusion:
The main findings of this study revealed that majority of the Participants were aware of the use of outcome measures in clinical practice, they perceived it as essential and useful, however, they have poor attitude and seldom make use of the Oms.
An audit of emergency response to terrorist-related bomb blasts and gunshot injuries
Authors: Amole Olushola , Amole Taiwo , Omeje Kelvin , Efunkoya Akinwale , Osunde Otasowie , Muhammad Muhammad Aminu , Aji Sani Ali , Ismail Hassan , Abubakar Mohammed , Akinlade Akinwaleola , Ahmed Rufai , Becker Torben 
Published: August 2023

Context:
The management of mass casualty events caused by terrorist-related suicide bombings in densely populated areas is often challenging.

Aims:
This study describes the pattern of injuries, the emergency response following a suicide bombing in Nigeria in 2014 and compares the outcomes to those of other incidents.

Settings and Design:
A retrospective analysis of cases that presented to a major tertiary care center was done.

Methods and Material:
Medical records of 50 patients who experienced bomb blast or gunshot wounds during 28th November, 2014 suicide bombing of the Kano Central Mosque were reviewed and 12 eyewitnesses were interviewed.

Statistical analysis used:
Descriptive analysis of quantitative data was done while major themes were identified from the key informant interviews.

Results:
Fifty patients were admitted at the acute care center within 4 hours. There was a male predilection (98%), with a median age of 30 years (IQR, interquartile range = 37.5 years). Most injuries were the result of multiple penetrating projectiles (secondary blast injuries), primarily involving blast-energized metallic fragments like screws, nails, bolts, ball bearings, and metal scraps. Eleven patients (22%) had minor lacerations, about a quarter (n = 12; 24%) had severe hemorrhage and were transfused, five (10%) had multi-system involvement, and mortality rate was 8% (n = 4). Interventions were aimed at preserving the lives of those injured.

Conclusion:
Most of the victims had major injuries which were appropriately managed although the hospital lacked an existing protocol on mass casualty management. Increased awareness, organized field triage mechanisms, and capacity building in health facilities will facilitate prompt emergency response.