bluuebunny/crossref_metadata_2025_split huggingface dataset:
Challenges and strategies to improve the provision of end‐of‐life cancer care in rural and regional communities: Perspectives from Australian rural health professionals
Authors: Cerni Jessica , Rhee Joel , Hosseinzadeh Hassan 
Published: May 2023

AbstractObjectiveTo identify challenges and strategies to improve the provision of end‐of‐life (EOL) cancer care in an underserved rural and regional Australian local health district (LHD) from the perspective of general practitioners (GPs) and specialist clinicians while exploring the benefits of adopting a generalist health care approach to delivering EOL care in rural and regional communities.SettingRural and regional Australia.ParticipantsGeneral practitioners and palliative care and cancer care specialists (medical and nursing) involved in the provision of EOL care to people with advanced cancer in the rural and regional areas of an Australian LHD.DesignQualitative descriptive study involving 22 participants in four face‐to‐face and online focus groups. Thematic analysis of the transcripts identified key issues affecting EOL care for people with advanced cancer in rural and regional areas of the LHD.ResultsFour themes including geographical remoteness, system structures, medical management and expertise and training emerged from the focus groups. Key barriers to effective EOL care included insufficient remuneration for GPs and other clinicians (especially home visits), resource limitations, limited community awareness of palliative care and lack of confidence and training of clinicians. Continuity of care was identified as an important facilitator to effective EOL care. Participants suggested greater Medicare rebates for palliative care and home visits, adequate equipment and resources, technology‐enabled clinician training and greater rural‐based training for specialist PC clinicians may improve the provision of EOL care in regional and rural communities.ConclusionsRural‐based clinicians delivering EOL cancer care appear to be disproportionately affected by geographical challenges including resource and funding limitations. A multi‐pronged strategy aimed at greater interdisciplinary collaboration, community awareness and greater resourcing and funding could help to improve the provision of EOL care in underserved rural and remote communities of Australia.
Right hemicolectomy for ascending colon cancer using the hinotori surgical robot system: The first ever case report for colon cancer
Authors: Miyo Masaaki , Okita Kenji , Okuya Koichi , Ito Tatsuya , Akizuki Emi , Ogawa Tadashi , Ishii Masayuki , Miura Ryo , Ichihara Momoko , Korai Takahiro , Kimura Akina , Takemasa Ichiro 
Published: May 2023

AbstractThe hinotori Surgical Robot System obtained pharmaceutical approval for use in colorectal cancer surgery in October 2022 in Japan, and its advantages, including its operating arm with eight axes, adjustable arm base, and flexible 3D viewer, are expected to be utilized in colon cancer surgery. A 68‐year‐old woman presented to our hospital with abdominal pain and was diagnosed with cStageIIa (cT3N0M0) ascending colon cancer and underwent right hemicolectomy using the hinotori Surgical Robot System with the appropriate port placement on the arc around the hepatic flexure, which was available for both ileocecal manipulation and lymph node dissection, and adjustment of the angle of the arm base to further reduce interference. Herein we report the world's first surgery for colorectal cancer using the hinotori Surgical Robot System.
Towards theorising corporate social irresponsibility: The Déjà Vu cases of collapsed forestry ventures
Authors: Leung Tiffany C. H. , Ng Artie W. , Hoepner Andreas G. F. , Harjoto Maretno A. 
Published: May 2023

AbstractBased on case studies and secondary data, this study theorises how and why firms engage in corporate social irresponsibility (CSIR). Using the inductive process of theory building based on case studies of two forestry companies operating in China, this study explains how and why organisations with initial intentions towards corporate social responsibility (CSR) engage in CSIR based on paths taken and the behaviours across micro (individual), meso (organisational), and macro (industry) levels. Hence, there is a ‘grey zone’ between CSR and CSIR (Clark, C. E., Riera, M., & Iborra, M. (2021). Business & Society, 61, 1473–1511. 10.1177/00076503211015911). This study extends the path dependence literature on CSIR (Küberling‐Jost, J.A. (2019). Journal of Business Ethics, 169(3), 579–601) by integrating moral disengagement and the theory of planned behaviour, stakeholder agency, and institutional theory into path dependence theory based on observed behaviours across micro, meso, and macro levels.
Agreement between maternal self‐report of birth‐related information and medical records in Brazil: A comparison study between public, mixed, and private hospitals
Authors: Nakamura‐Pereira Marcos , Takemoto Maíra Libertad Soligo , Bittencourt Sônia Duarte de Azevedo , Viellas Elaine Fernandes , do Carmo Cléber Nascimento , Schilithz Arthur Orlando Corrêa , Theme Filha Mariza Miranda , Leal Maria do Carmo 
Published: May 2023

AbstractBackgroundThe study aims to assess agreement between data obtained from interviews with postpartum women and their health records about labor and birth characteristics, newborn care, and reasons for cesarean birth.MethodsThe present study analyzes the Birth in Brazil study dataset, a nationwide hospital‐based survey that included 23,894 postpartum women. Reliability was assessed using kappa coefficients and 95% confidence intervals. We also calculated the proportion of specific agreement: the observed proportion of positive agreement (Ppos) and the observed proportion of negative agreement (Pneg).ResultsIn terms of labor and birth characteristics, more significant discrepancies in prevalence were observed for fundal pressure (1.4%–42.6%), followed by amniotomy, and augmentation. All of these variables were reported more frequently by women. Reliability was nearly perfect only for mode of delivery (kappa 0.99–1.00, Ppos and Pneg >99.0%). Higher discrepancies in reasons for cesarean prevalence were observed for previous cesarean birth (CB) (3.9%–10.4%) and diabetes mellitus (0.5%–8.5%). Most kappa coefficients for CB reasons were moderate to substantial. Lower coefficients were seen for diabetes mellitus, induction failure, and prelabor rupture of membranes and Pneg was consistently higher than Ppos.DiscussionOur findings raise relevant questions about the quality of information shared with women during and after the process of care for labor and birth, as well as the information recorded in medical charts. Not having access to full information about their own health status at birth may impair women's health promotion behaviors or clear disclosure of risk factors in future interactions with the healthcare system.
Snow damage in a Himalayan forest maintains the dominance of evergreen oaks
Authors: Thadani Rajesh 
Published: May 2023

AbstractExtreme climate events are increasing due to climate change. Heavy snowfall in a Himalayan evergreen oak forest damaged 21% trees and created large treefall gaps. Such occasional events may help define the upper altitudinal boundary of certain species. Oak trees with branches lopped by local communities showed lower damage.
Reduced dosing versus full dosing valganciclovir for prophylaxis of cytomegalovirus in high‐risk abdominal transplant recipients
Authors: Kreiser Maura L. , Dupuis Robert , Szempruch Kristen R. , Chargualaf Laura M. 
Published: May 2023

AbstractBackgroundCytomegalovirus (CMV) is a common infection in abdominal transplant recipients (ATR). Prevention of CMV in the highest risk population (CMV IgG donor+/recipient‐) is critical as CMV is associated with negative outcomes. Guideline recommended prophylactic valganciclovir dosing is 900 mg daily for 6 months in this population. However, reduced dosing strategies are utilized in practice.MethodsThis single center, retrospective study in adult ATR compared full valganciclovir prophylactic dosing (900 mg daily for 6 months) to reduced dosing (900 mg daily for 3 months, then 450 mg daily for 3 months). The primary endpoint was incidence of CMV infection with viral load >1000 IU/mL. Secondary endpoints included incidence of CMV infection with viral load 200–1000 IU/mL, neutropenia, and leukopenia.ResultsIncidence of CMV infection with viral load >1000 IU/mL (29% vs. 27%, p = 1) or CMV infection with viral load 200‐1000 IU/mL (6% vs. 12%, p = .421) did not differ significantly between 68 ATR in reduced and full dosing groups, as well as incidence of leukopenia (94% vs. 97%, p = 1) and neutropenia (77% vs. 70%, p = .586).ConclusionsThere was no difference in the incidence of CMV infection, neutropenia, or leukopenia of the two dosing regimens, although time to CMV diagnosis was different.
Advancing therapy in people with suboptimally controlled basal insulin‐treated type 2 diabetes: Subanalysis of the SoliMix trial in participants in Latin American countries
Authors: Frechtel Gustavo , Sauque‐Reyna Leobardo , Choza‐Romero Ricardo , Anguiano Luis , Melas‐Melt Lydie , Sañudo‐Maury María Elena 
Published: May 2023

AbstractAimsThis subanalysis of the SoliMix trial assessed the efficacy and safety of advancing basal insulin (BI) therapy with iGlarLixi versus BIAsp 30 in people with type 2 diabetes (T2D) living in Latin American (LATAM) countries, i.e. Argentina and Mexico (N = 160).Materials and MethodsSoliMix (EudraCT: 2017‐003370‐13) was a 26‐week, open‐label, multicentre study, where adults with T2D suboptimally controlled with BI plus one or two oral glucose‐lowering drugs and glycated haemoglobin (HbA1c) ≥7.5% to ≤10% were randomized to once‐daily iGlarLixi or twice‐daily BIAsp 30. Primary efficacy endpoints were non‐inferiority in HbA1c reduction (margin 0.3%) or superiority in body weight change for iGlarLixi versus BIAsp 30.ResultsBoth primary efficacy endpoints were met in the LATAM region. After 26 weeks, HbA1c was reduced by 1.8% with iGlarLixi and 1.4% with BIAsp 30, meeting non‐inferiority [least squares mean difference −0.47% (95% confidence interval: −0.82, −0.11); p < .001]. iGlarLixi was superior to BIAsp 30 for body weight change [least squares mean difference −1.27% (95% confidence interval: −2.41, −0.14); p = .028]. iGlarLixi was also superior to BIAsp 30 for HbA1c reduction (p = .010). A greater proportion of participants achieved HbA1c <7% without weight gain and HbA1c <7% without weight gain and without hypoglycaemia with iGlarLixi versus BIAsp 30. Incidence and rates of American Diabetes Association Level 1 and 2 hypoglycaemia were lower with iGlarLixi versus BIAsp 30.ConclusionsOnce‐daily iGlarLixi provided better glycaemic control with weight benefit and less hypoglycaemia than twice‐daily premix BIAsp 30. iGlarLixi may be a favourable alternative to premix BIAsp 30 in people with suboptimally controlled T2D to advance BI therapy in the LATAM region.
Machine‐learning‐derived heart and brain age are independently associated with cognition
Authors: Iakunchykova Olena , Schirmer Henrik , Vangberg Torgil , Wang Yunpeng , Benavente Ernest D. , van Es René , van de Leur Rutger R. , Lindekleiv Haakon , Attia Zachi I. , Lopez‐Jimenez Francisco , Leon David A. , Wilsgaard Tom 
Published: May 2023

AbstractBackground and purposeA heart age biomarker has been developed using deep neural networks applied to electrocardiograms. Whether this biomarker is associated with cognitive function was investigated.MethodsUsing 12‐lead electrocardiograms, heart age was estimated for a population‐based sample (N = 7779, age 40–85 years, 45.3% men). Associations between heart delta age (HDA) and cognitive test scores were studied adjusted for cardiovascular risk factors. In addition, the relationship between HDA, brain delta age (BDA) and cognitive test scores was investigated in mediation analysis.ResultsSignificant associations between HDA and the Word test, Digit Symbol Coding Test and tapping test scores were found. HDA was correlated with BDA (Pearson's r = 0.12, p = 0.0001). Moreover, 13% (95% confidence interval 3–36) of the HDA effect on the tapping test score was mediated through BDA.DiscussionHeart delta age, representing the cumulative effects of life‐long exposures, was associated with brain age. HDA was associated with cognitive function that was minimally explained through BDA.
Alternative approach for fracture fixation following implant infection in aSalter‐Harris type‐IIfracture of the proximal phalanx in a Warmblood foal
Authors: Kalinovskiy Andrey , Ehrle Anna , Müller Eva , Lischer Christophorus 
Published: May 2023

SummaryA 2‐day‐old female Warmblood foal (70 kg) presented with a closed, displaced Salter‐Harris type‐II fracture of the proximal physis of the left hind first phalanx. The fracture was repaired with four 4.5 mm cortical screws and a wire in a figure‐of‐8 pattern applied on the lateral and medial aspect of the phalanx, respectively. A 4.5 mm cortical screw was additionally inserted in lag‐fashion to engage the lateral metaphyseal spike. Three days postoperatively, medial and proximal displacement of the distal fracture fragment and implant infection were apparent and revision surgery was performed. Previous implants were removed and two 4.5 mm transphyseal cortical lag‐screws were placed in proximolateral–distomedial and dorsoproximal–plantarodistal direction across the physis and the fracture line. Postoperatively, the fracture healed rapidly and the implants were removed 6 weeks later. Nineteen months after implant removal, the horse did not show any sign of lameness, despite a shortening of the proximal phalanx compared to the contralateral limb. In cases of postoperative implant instability and infection, implant removal often becomes necessary. However, new implants cannot be placed safely in the previous location. To avoid this problem, this report describes an alternative approach for screw positioning in case of previous implant infection in a Salter‐Harris type‐II fracture of the proximal physis of the first phalanx.
Undifferentiated sarcomas in humans and veterinary species
Authors: Hollis Anna R. 
Published: May 2023

SummaryUndifferentiated sarcomas, more correctly known as undifferentiated pleomorphic sarcomas (UPS), are a form of soft tissue sarcoma. They appear to be uncommonly diagnosed in veterinary species but represent the second most common form of soft tissue sarcoma in human adults. There is an evolving nomenclature around these tumours, with older reports referring to ‘malignant fibrous histiocytoma’, but these have been reclassified into several different tumour types, including the UPS. This makes review of the literature challenging, as many tumours previously referred to as malignant fibrous histiocytomas have been reclassified and are not the same as the UPS.En blocsurgical excision is the mainstay of treatment in all species, although adjunctive radiotherapy and perioperative chemotherapy improve the prognosis in humans, and should be considered in horses diagnosed with this tumour type. Metastasis is uncommon in all species but can be devastating when it occurs.
A new method of multi‐attribute group decision making based on hesitant fuzzy soft expert information
Authors: Akram Muhammad , Ali Ghous , Alcantud José Carlos R. 
Published: May 2023

AbstractInteresting insights into uncertain multi‐attribute decision‐making systems have come from the theory of hesitant fuzzy sets. Outputs become more reliable when a decision‐maker is not forced to produce one single assessment in the presence of hesitation. Hesitancy in fuzzy environments grants more flexibility to the decision‐maker, therefore enhancing the validity of all subsequent results. Due to these facts, hesitation has become a landmark in the enhancement of fuzzy‐soft‐inspired theories, and techniques using models such as hesitant fuzzy soft sets or hesitant (fuzzy) ‐soft sets have thrived. However, the literature lacks a comparable improvement for fuzzy soft expert information. The main goal of this paper is the integration of both hesitation and fuzziness with the characteristics of soft expert sets. The resulting hybrid model is therefore called hesitant fuzzy soft expert set, and its utilization for multiple attribute group decision‐making (MAGDM) will be investigated too. To that purpose, we first study the required algebraic operations and properties (subsethood and equality, complement, union, intersection, plus AND and OR operation). Respective numerical examples illustrate their utilization. We also establish some important laws for hesitant fuzzy soft expert sets, including commutativity, associativity, distributivity, and De Morgan's laws. Moreover, we define four novel types of level soft expert sets for fuzzy soft expert sets, and three types of fuzzy soft expert sets for hesitant fuzzy soft expert sets, which are: ‐level soft expert sets, level soft expert sets regarding fuzzy threshold, mid‐level soft expert sets and top‐level soft expert sets. Armed with these tools, we present a natural algorithm for MAGDM under hesitant fuzzy soft expert information that is accompanied by an illustrative application that concerns a selection problem for the samples of electric vehicles manufactured by different companies. This is followed by a comparison with existing mathematical tools such as hesitant fuzzy soft sets and fuzzy soft expert sets, in order to show the advantages of our work over them. In the end, we provide some future research directions.
Maritime temporalities and capitalist development
Authors: Colás Alejandro , Campling Liam 
Published: May 2023

AbstractThis intervention develops arguments in our book Capitalism and the Sea on the complex temporalities attached to capitalism's intense and peculiar relationship to the global ocean. Technological innovations like the steamship or containerisation plainly transformed the pace and intensity of maritime commerce, and aspects of the global economy. We take this further to argue that the very origins and periodisation of capitalism are connected to the global ocean; as will be our futures, given the unpredictable implications of the oceans acting as the biosphere's ‘heat sink’. We consider several stylised expressions of time at sea: deep‐time, logistical‐time, life‐time, and revolutionary time suggesting that the ocean world as a geographical space articulates these in distinctive and contradictory ways.
From the cocoon to la chape de plomb: The birth and persistence of silence around sexism in academia
Authors: Shymko Yuliya , Vershinina Natalia , Daskalaki Maria , Azevedo Guilherme , Quental Camilla 
Published: May 2023

AbstractDrawing on narrative accounts of French business school staff and faculty about their experiences and observations of actions taken by different organizational actors in response to a trigger event, we theorize the intricate connections between organizational practices conducive to sexism and the persistence of silence around such practices. Specifically, empirical investigation demonstrates how managerial practices such as the allocation of organizational tasks and valorization of individual contributions prompt organizational members to assume a variety of stances toward gender issues. The enactment of these stances in various interactions provokes organizational counteraction in the form of sanctions, the establishment of a hermetic and formulaic communication regime, and public reinforcement of meritocratic narratives. This results in silence around organizational sexism manifesting as a collective and individual inability and unwillingness to react. This study contributes to a broader and rapidly developing literature on sexism in academic settings and the phenomenon of silencing in organizations by shedding light on the mechanisms of its persistence.
Evaluation of Dual Domain Mass Transfer in Porous Media at the Pore Scale
Authors: Dorchester Leland , Day‐Lewis Frederick D. , Singha Kamini 
Published: May 2023

AbstractDual‐porosity models are often used to describe solute transport in heterogeneous media, but the parameters within these models (e.g., immobile porosity and mobile/immobile exchange rate coefficients) are difficult to identify experimentally or relate to measurable quantities. Here, we performed synthetic, pore‐scale millifluidics simulations that coupled fluid flow, solute transport, and electrical resistivity (ER). A conductive‐tracer test and the associated geoelectrical signatures were simulated for four flow rates in two distinct pore‐scale model scenarios: one with intergranular porosity, and a second with an intragranular porosity also defined. With these models, we explore how the effective characteristic‐length scale estimated from a best‐fit dual‐domain mass transfer (DDMT) model compares to geometric aspects of the flow field. In both model scenarios we find that: (1) mobile domains and immobile domains develop even in a system that is explicitly defined with one domain; (2) the ratio of immobile to mobile porosity is larger at faster flow rates as is the mass‐transfer rate; and (3) a comparison of length scales associated with the mass‐transfer rate (Lα) and those associated with calculation of the Peclet number (LPe) show LPe is commonly larger than Lα. These results suggest that estimated immobile porosities from a DDMT model are not only a function of physically mobile or immobile pore space, but also are a function of the average linear pore‐water velocity and physical obstructions to flow, which can drive the development of immobile porosity even in single‐porosity domains.
Volumetric changes in root canal sealers in ex vivo and a novel animal model approach
Authors: Ferreira Cláudio Malizia Alves , de Lima Carolina Oliveira , Pinto Karem Paula , Barbosa Ana Flávia Almeida , de Souza Jenif Braga , De‐Deus Gustavo , Sassone Luciana Moura , Silva Emmanuel J. N. L. 
Published: May 2023

AbstractAimThis study aimed to evaluate the volumetric change of root canal sealers through micro‐computed tomographic analysis using a novel in vivo model and to compare the results with those obtained using an ex vivo test.MethodologyEighteen single‐rooted teeth were cut to 5 mm length from the root apex. The root canals were uniformly enlarged and filled with EndoSequence BC Sealer or AH Plus Jet root canal sealers. Samples were stored at 37°C and 95% relative humidity for 24 h and then scanned with a micro‐CT device. Twelve samples (n = 6 for each sealer) were implanted in the subcutaneous tissue of Wistar rats, while six samples (n = 3 for each sealer) were immersed in 20 mL of phosphate‐buffered saline (PBS) at 37°C at neutral pH. After 7 and 30 days, teeth were removed from subcutaneous tissue or PBS and rescanned. Statistical analysis of volume changes was performed using Shapiro–Wilk's test and independent t‐test (p < .05).ResultsAH Plus Jet had smaller volume changes (−2.2 to +0.77%) than EndoSequence BC Sealer (−2.0 to +4.0%) (p < .05), in the two tested models. The volume of the root canal sealers decreased over time (p < .05), in vivo. AH Plus Jet results varied between the in vivo and ex vivo results (p < .05), while EndoSequence BC Sealer presented similar volume losses for both experimental models (p > .05).ConclusionEndoSequence BC Sealer lost more volume than AH Plus Jet. The experimental conditions influenced the volumetric change of AH Plus Jet but not the EndoSequence BC Sealer. The ex vivo model should be further explored as a methodological alternative to assess the volumetric changes of root canal sealers without causing harm to animals.