bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of the ozonated sunflower oil application on reducing sensitivity after at-home bleaching
Authors: Roque João Vitor Oribka , Mendonça Márcio José , Vanolli Rafael da Silva , Campos Francisco Ubiratan Ferreira , Ueda Julio Kathuide , Colognese Maria Ritha Veiga , Silva Marina Pereira , Camilotti Veridiana 
Published: June 2023

Abstract
Objectives
Due to controversial results in relation to the influence of desensitizing agents on sensitivity during bleaching, the present study evaluated the degree of tooth bleaching sensitivity, color change, and patient acceptability of desensitizing agents containing potassium nitrate/sodium fluoride (PNF) or ozonized sunflower oil associated with in-office bleaching with 35% hydrogen peroxide (HP).
Materials and Methods
A clinical trial was conducted with a split-mouth design. The sample consisted of 30 volunteers randomized into 2 experimental groups according to the desensitization protocol. Potassium nitrate and sodium fluoride was applied to the hemiarch corresponding to the control group for 10 minutes, while in the hemiarch of the test group, ozonized sunflower oil was applied for 2 minutes with a rubber cup in low rotation, followed by a potassium nitrate and sodium fluoride application for 10 minutes. In sequence, both arcades were bleached with 35% hydrogen peroxide for 50 minutes.
Results
Previous application of ozonated sunflower oil resulted in a significant reduction in sensitivity in the first 24 hours after removal of the bleaching gel, as well as the test group showed lower tooth sensitivity in times measured up to 1 hours after removal of the bleaching gel.
Conclusions
Both experimental groups presented satisfactorily lighter shades, but no statistically significant differences were observed regardless of the desensitization protocol employed.
Clinical relevance
The combined use of ozonated sunflower oil followed by a potassium nitrate and sodium fluoride-based desensitizing agent results in reduced sensitivity compared to the desensitizing agent alone.
Unlabeled Data Selection for Active Learning in Image Classification
Authors: Li Xiongquan , Lu Yao , Fu Hongpeng , Wu Ying Cheng 
Published: June 2023

Abstract
Active Learning has emerged as a viable solution for addressing the challenge of labeling extensive amounts of data in data-intensive applications such as computer vision and neural machine translation. The main objective of Active Learning is to automatically identify a subset of unlabeled data samples for annotation. This identification process is based on an acquisition function that assesses the value of each sample for model training. In the context of computer vision, image classification is a crucial task that typically requires a substantial training dataset. This research paper intro-duces innovative selection methods within the Active Learning framework, aiming to identify informative images from unlabeled datasets while minimizing the number of required training data. The proposed methods, namely Similarity-based Selection, Prediction Probability-based Selection, and Competence-based Active Learning, have been extensively evaluated through experiments conducted on popular datasets like Cifar10 and Cifar100. The experimental results demonstrate that the proposed methods outperform random selection and conventional selection techniques. The superior performance of the novel selection methods underscores their effectiveness in enhancing the Active Learning process for image classification tasks.
Multianalytical approach to the exceptional Late Roman shipwreck of Ses Fontanelles (Mallorca, Balearic Islands)
Authors: Cau-Ontiveros M. Á. , Bernal-Casasola D. , Pecci A. , Fantuzzi L. , Picornell-Gelabert Ll. , Valenzuela A. , Retamosa J. A. , Portillo J. L. , Cardell J. , Llabrés S. Munar , Fuertes C. Juan , Riaza E. García 
Published: June 2023

Abstract
The paper presents the results of an interim analytical approach to the Late Roman shipwreck of Ses Fontanelles recently found in the island of Mallorca (Balearic Islands, Spain). The excellent state of preservation of the hull and the cargo, including amphorae with painted inscriptions (tituli picti), and its location in shallow waters offshore of one of the main touristic beaches of the island makes this a unique finding in the Mediterranean. A first season of excavations and study of the cargo triggered an analytical approach to solve some of the problems pose by archaeological research, mainly related to the possible origin of the vessel. The analytical strategy combines petrographic analysis for the study of the provenance of the amphorae, archaeozoology and residue analysis to identify their content, and analysis of the wood and plant remains to understand the use of vegetal resources in shipbuilding and in the stow of the cargo. The results of the combination of the petrographic analysis, the study of the ichthyofauna and the organic residue analysis suggest that the boat probably departed from the area of Cartagena in the southeastern part of the Iberian Peninsula, carrying a cargo of fish sauce (liquaminis flos), oil, and probably olives preserved in wine derivatives, transported in three main types of amphorae. The analysis of the wood shows, as known in Roman shipbuilding, a clear selection of forest resources. The shipbuilders used pine for longitudinal parts of the hull, while for the small pieces related to the assemblage system (pegged, mortise and tenons) and subjected to a great stress they selected harder woods mainly Cupressaceae, Olea europaea, and Laurus nobilis. In addition, the study reveals that mainly branches of Vitis vinifera, but also other herbaceous plants were used as dunnage protecting the cargo during the journey. The results help to shed some light into different aspects of this unique vessel sunk in Mallorcan waters and contributes to show the benefit of applying archaeological sciences in maritime archaeology.
Comparison of Diet with and Without Strengthening Exercises Impacting Non-Specific Chronic Low Back Pain Patients in Obesity
Authors: Sarfraz Muhammad , Shadmehr Azadeh , Ahmed Javeria , Bhutto Mazhar Ali , Jalaie Shohreh 
Published: June 2023

Abstract
Aims:
The purpose of this study was to compare the effects of two commonly practiced techniques of weight reduction and their impact on Non-specific low back pain in obese clients.
Methods:
52 patients with sedentary lifestyle, age between 25–40 years were assigned in two groups according to their BMI (Grade I & II obesity) and were assessed for their weight, Body Mass index (BMI), Waist to hip ratio (WHR), Body Fat Percentage (BF %), Fat mass (FM), lean Mass (LM), Numeric Pain rating scale (NPRS), Oswestry Disability Index (ODI) and pushups for muscular endurance and strength. One of the group followed diet only (D) while the other followed diet plus strength (DS) training. After 6 weeks’ intervention, clients were assessed again on same parameters. SPSS 21 version was used to analyze the results.
Result:
DS group revealed positive changes in all parameters i.e, weight (0.00), BMI (0.00), WHR (0.01), BF% (0.00), FM (0.00), LM (0.01), NPRS (0.00), OLBPD (0.00), pushups (0.00), while D group showed insignicant results in WHR (p value- 0.736, before 0.88 ± 0.1 after 0.88 ± 0.1), LM (p-value- 0.384, before 40.9 ± 8.9 after 40.3 ± 8.8) and Pushups (p value 0.384, before 4.6 ± 3.4 after 4.3 ± 3.7).
Conclusion:
6 weeks of diet and diet plus strength training resulted in bringing about the positive changes in pain and Oswestry disability index but in all parameters diet plus strength exercise group overweighed the diet only group.
Polygenic risk score predicting susceptibility and outcome of benign prostatic hyperplasia in the Han Chinese
Authors: Hung Sheng-Chun , Chang Li-Wen , Hsiao Tzu-Hung , Lin Guan-Cheng , Wang Shian-Shiang , Li Jian-Ri , Chen I-Chieh 
Published: June 2023

Abstract
Importance:
Polygenic risk score (PRS) is effective in predict benign prostatic hyperplasia (BPH) incidence, prognosis and risk of operation in Han Chinese.
Objective:
The aim of our study is to investigate the role of PRS for BPH incidence and treatment outcome through hospital-based genome-wide association study (GWAS).
Design, setting, and participants:
The Affymetrix Genome-Wide TWB 2.0 SNP Array genotyped 6,237 male participants with benign prostatic hyperplasia (BPH) and 17,170 non-BPH controls from the Taiwan Precision Medicine Initiative (TPMI). PRS was determined using PGS001865, which included 1,712 single nucleotide polymorphisms. PRS scores were categorized into quartiles (Q1-Q4) and their association with outcomes in BPH patients was analyzed using logistic regression models.
Main outcomes and measures:
We investigated the PRS association with BPH incidence, adjusting for age and PSA levels. We explored PSA's relationship with prostate volume and assessed 5ARI treatment response via percentage reduction in prostate volume per patient. Additionally, we studied the PRS association with TURP risk.
Results:
In a cohort of 23,407 men, 6,237 were diagnosed with BPH. Risk of BPH was higher in the fourth quartile (Q4) than the first quartile (Q1) (OR=1.34, 95% CI=1.24-1.46, p<0.0001), even after adjusting for age (OR=1.39, 95% CI=1.27-1.52, p<0.0001). The Q4 group had larger prostate volume (43.1 ± 25.0 ml) than Q1 (34.6 ± 19.0 ml) (p<0.001), and less volume reduction after 5ARI treatment (Q1: 29.9 ± 16.6 ml, Q4: 25.0 ± 18.6 ml, p=0.011). Q1 had lower cumulative TURP probability at 3, 5, and 10 years compared to Q4 (p=0.045, p=0.009, p<0.001, respectively). PRS Q4 was an independent TURP risk in multivariate COX hazard regression (HR=1.45, 95% CI=1.09-1.92, p=0.012).
Conclusions and relevance:
In this hospital-based cohort, a higher PRS was associated with the susceptibility to BPH in male Han Chinese. In patients with BPH, a higher PRS was associated higher PSA level, larger prostate volume, inferior response of 5ARI and higher risk of TURP. Age, PSA and prostate volume were also independent risk of TURP. Prospective large-scale study with longer follow-up would be needed to validate our result.
Effects of condensed tannins on bacterial and fungal communities during aerobic exposure in sainfoin silage
Authors: Huang Rongzheng , Zhang Fanfan , Ma Chunhui , Wang Xuzhe 
Published: June 2023

Abstract
Sainfoin is a forage legume that is widely distributed around the world and is beneficial for animals owing to the characteristics of its condensed tannins (CTs), which, from certain plants, can prolong the aerobic stability of silage. The present study investigated whether sainfoin CTs can prolong aerobic stability by adding polyethylene glycol (PEG) to inactivate CTs activity in the silage system. The results showed that the aerobic stability increased under the PEG treatment (P < 0.05). The pH (4.62 vs. 4.53; P < 0.05) was lower while the ammonia nitrogen (0.71 g ammonia nitrogen/kg dry matter (DM) vs. 0.94 g/kg DM; P < 0.05) was higher in the PEG-treated group compared with the control after 3 d of aerobic exposure. The crude protein content decreased by 5.93% in the PEG-treated group during 7 d of aerobic exposure. BA was detected only in the PEG-treated group upon aerobic exposure. Yeasts were more abundant in the control compared with the PEG-treated group after 7 d of aerobic exposure (4.32 vs. 4.08 Log10 CFU/g, fresh weight basis, P < 0.05), after which the relative abundance of Lactobacillus was lower in the PEG-treated group (65.01% vs. 75.01% in the control; P < 0.05), while the relative abundance of Pediococcus was higher in the PEG-treated group compared with the control (10.9% vs. 4.49%, respectively; P < 0.05). Wickerhamomyces was dominant in both groups after 7 d of aerobic exposure, with no difference between groups (P > 0.05). The relative abundances of Apiotrichum and Aspergillus were lower in the control than in the PEG-treated group after 7 d of aerobic exposure (2.28 vs. 8.63% for Apiotrichum and 0.58 vs. 7.19% for Aspergillus, respectively; P < 0.05). The results suggested that sainfoin CTs decreased aerobic stability, but could inhibit certain bacteria and fungi, such as Pediococcus and Apiotrichum, and preserve the protein content during the aerobic exposure of silage.
Protective Effects of Aureobasidium pullulans Lysate on UV-damaged Human Skin Fibroblasts and HaCaT Cells
Authors: Wang Xin , Zhang Yongtao , Wang Dongdong , Su Ning , Yang Li , Fu Hao , Zhang Jiachan , Li Meng , Wang changtao 
Published: June 2023

Abstract
Background
Aureobasidium pullulans has a wide range of applications. Ultraviolet (UV) rays from the sun can cause skin photoaging. In order to explore the protective effect and application potential of A.pullulans lysate on UV-damaged Human Skin Fibroblasts (HSF) and HaCaT Cells, this study investigate the anti-aging and anti-inflammatory effects of A.pullulans lysate and the mechanism of anti-oxidative stress from the cellular and molecular levels through cytotoxicity experiments, enzyme-linked immunosorbent assay (ELISA) and real-time reverse transcription-polymerase chain reaction (qRT-PCR).
Results
The experimental results showed that the A.pullulans lysate reduced the loss of extracellular matrix components (EMC) such as collagen and hyaluronic acid(HA), cleared excessive reactive oxygen species( (ROS)) in the body, increased catalase activity, reduced the expression of intracellular matrix metalloproteinases (MMPs), and enhanced the gene expression of metalloproteinases inhibitor (TIMP), reduced the content of inflammatory factors, and regulated the balance of oxidative stress through Nrf2/Keap1 and MAPK signaling pathways.
Conclusions
This study shows that the A.pullulans lysate has the potential to resist photoaging.
Effect of Contact Inhibition Location on confined cellular organization
Authors: Potdar Harshal , Pagonabarraga Ignacio , Muhuri Sudipto 
Published: June 2023

Abstract
Experiments performed using micro-patterned one dimensional collision assays have allowed a precise quantitative analysis of the collective manifestation of contact inhibition locomotion (CIL) wherein, individual migrating cells reorient their directionof motion when they come in contact with other cells. Inspired by these experiments, we present a discrete, minimal 1D Active spin model that mimics the CIL interaction between cells in one dimensional channels. We analyze the emergent collective behaviour of migrating cells in such confined geometries, as well as the sensitivity of the emergent patterns to driving forces that couple to cell motion. In the absence of vacancies, akin to dense cell packing, the translation dynamics is arrested and the model reduces to an equilibrium spin model which can be solved exactly. In the presence of vacancies, the interplay of activity-driven translation, cell polarity switching, and CIL results in an exponential steady cluster size distribution. We define a dimensionless Péclet number Q - the ratio of the translation rate and directional switching rate of particles in the absence of CIL. While the average cluster size increases monotonically as a function of Q, it exhibits a non-monotonic dependence on CIL strength, when the Q is sufficiently high. In the high Q limit, an analytical form of average cluster size can be obtained approximately by effectively mapping the system to an equivalent equilibrium process involving clusters of different sizes wherein the cluster size distribution is obtained by minimizing an effective Helmholtz free energy for the system. The resultant prediction of exponential dependence on CIL strength of the average cluster size and Q1/2 dependence of the average cluster size is borne out to reasonable accuracy as long as the CIL strength is not very large.
Automatic Power Trace Alignment for Side-Channel Analysis
Authors: Wang Sying-Jyan , Lin Yi-Chi , Li Katherine Shu-Min , Lin Chen-Yeh , Chong Song-Kong 
Published: June 2023

Abstract
Data encryption is critical for information security. Previous studies show that power analysis is a powerful tool for side-channel attack (SCA) against cryptographic modules. Therefore, it is essential to carry out power analysis to assess the vulnerability of cryptographic modules. The success of power analysis relies on aligned power traces, which is not easy without an external trigger point. Locating cryptographic operations in a power trace can be tedious, so it is desirable if we can achieve automatic power trace alignment. In this paper, we propose an automatic power trace alignment method so that operations in power traces and be located without external trigger points. Experimental results show that the proposed method can be applied to various ciphers, including AES, RSA, and ECC.
Supramolecular architecture of a novel non-centrosymmetric heteromolybdate hybrid for nonlinear optical applications: structure, characterization, stability study and DFT calculations
Authors: Djeribi Malek , Nagazi Ichraf , Dege Necmi , Issaoui Noureddine , Haddad Amor 
Published: June 2023

Abstract
A novel non-linear optical organic–inorganic material based on three-dimensional (3D) Strandberg-type polyoxoselenomolybdate, (C6H14N2)2[Se2Mo5O21]·2.6 H2O (I) has been successfully obtained by solution process and characterized by scanning electron microscopy, infrared and ultraviolet spectroscopy, thermogravimetric analysis, cyclic voltammetry measurement. The electronic and electrochemical stability behaviour of the compound was evaluated as a function of pH and time via UV-visible spectroscopy and cyclic voltametry. Single X-Ray diffraction was used for complete structure elucidation which confirms the title compound crystallizes in the non-centrosymmetric orthorhombic space group P212121 thus allowing non-linear optical properties. The supramolecular framework exhibits a periodic arrangement of Strandberg clusters anions [Se2Mo5O21]4– connected to each other with water molecules and Dabconium organic cations through a network of hydrogen bonds. The intermolecular interactions which ensure the cohesion between different entities were ‎analysed by density functional theory calculations and Hirshfeld surface analysis. DFT ‎calculations with different functionals have been used to better understand several properties. A good agreement was found between the experimental and computational results.
The Neonatal-Perinatal Medicine Fellowship Application Webinar Series: A Novel Approach to Helping Applicants Succeed
Authors: Bartlett Michelle , Ribar Ellen , Zheng Yingying , Amiri Sasha , Dyess Nicolle Fernández , Lucke Ashley , French Heather 
Published: June 2023

Abstract
Background
In 2022, 13,586 candidates applied to subspecialty fellowships. Formal resources to inform candidates on subspecialty-specific fellowship application are limited. Candidates rely on residency application experience, informal advice, and online research for navigating the application process. Thus, a need exists for formal subspecialty-specific fellowship application guidance. The American Academy of Pediatrics Organization of Neonatal-Perinatal Medicine Training Program Directors (ONTPD) and Trainees and Early Career Neonatologists (TECaN) created a webinar-based curriculum to help educate trainees about the application process and recruit diverse fellowship applicants.
Methods
In 2022, ONTPD and TECaN co-hosted and implemented a four-part national webinar series focused on different aspects of the Neonatal-Perinatal Medicine (NPM) fellowship application and interview processes. Webinars were advertised through list-servs and social media, conducted in two time zones, and recorded for asynchronous viewing. Registration, demographic data, and questions for webinar panelists were collected via electronic survey. Program evaluation data was collected after each webinar and following the fellowship match.
Results
In the 2022 appointment year, 310 candidates participated in the NPM fellowship match and 250 individuals registered for the webinar series. A quarter (26%) of registrants identified as underrepresented in medicine. Most registrants reported minimal or no knowledge of the fellowship application (64%, 158/248) and interview (81%, 201/248) processes. The majority of registrants (70%, 173/248) were planning on applying to fellowship in 2022, and 91% of post-webinar respondents (43/47) felt the webinars were moderately or extremely helpful, a finding that was sustained beyond the match (37/42). Almost all respondents rated the quality of the webinars as good or higher and were likely or very likely to recommend them to peers (39/42). There was considerable variability amongst respondents in the number of fellowship programs applied to, interviewed at, and ranked, and factors influencing rank list.
Conclusion
We describe a virtual curriculum to prepare trainees for the NPM fellowship application and interview process. This webinar series provides needed education to fellowship candidates, bridges the gap between candidate knowledge and program director expectations, is generalizable to other specialties, and can be replicated with minimal resources.
Laser Trimming and Performance Analysis of Mill-grinding Tools for Carbon Fiber Reinforced Plastics
Authors: Liu Li , Yao Peng , Zhang Heyong , Chu Dongkai , Qu Shuoshuo , Huang Chuanzhen 
Published: June 2023

Abstract

Carbon fiber reinforced plastics (CFRP) are widely used in the aeronautic aerospace and manufacturing industries due to their excellent performance. However, Due to the structural characteristics of CFRP, its processing efficiency is low, the surface quality is poor, and it is easy to cause tool wear. In this study, the effect of tool type (conventional milling tool, rhombus tooth milling tool, electroplating mill-grinding tool, slotted mill-grinding tool, laser trimmed milling-grinding tool) and processing parameters (spindle speed, feeding speed, radial cutting depth) on tool life, processing quality and accuracy was systematically studied. The cutting force of the three types of electroplated diamond mill-grinding tools and the surface roughness of the processed CFRP are smaller than that of the conventional milling tool, and larger than that of the rhombus tooth milling tool. The main cutting and radial force of the trimming mill-grinding tool is 9.5 N, 1.26 N, respectively. The surface roughness is about 2.524 µm. Due to the laser trimmed mill-grinding tool has neat and sharp edges which can shear carbon fiber effectively, there is no obvious burrs on the processed CFRP. Moreover, the processed surface roughness was significantly reduced, and only slight wear of the tool was occurred. More importantly, since the processing debris can easily flow out of the straight groove of the laser trimmed mill-grinding tool, resulting in a sharp edge of the tool, which would reduce the cutting force. The overall processing performance of the laser trimmed mill-grinding tool is close to that of CFRP special tool (rhombus tooth milling tool), but its price is about one-fiftenth that of special tools. Therefore, the electroplated diamond milling tool with improved structure and optimized processing parameters can be an ideal tool for mill-grinding CFRP.