bluuebunny/crossref_metadata_2025_split huggingface dataset:
Laser Iridotomy for Pupillary Block in Children with Endogenous Uveitis
Authors: Arestova N. N. , Katargina L. A. , Denisova E. V. , Kruglova T. B. , Egiyan N. S. 
Published: April 2023

Objective. Development of a differential approach to laser iridotomy in children with endogenous uveitis considering iris characteristics and the reaction of children’s eyes to different laser types.Patients and methods. Thirty-six laser iridotomies were conducted in 36 children aged 8–16 years with pupillary block. Nidek YAG laser was used in YAG (1064 nm) and SLT (532 nm) modes.Results. The frequency of hemorrhagic complications during surgery decreased to 19.4 % since 2009. The frequency of exudative reactions and proliferative syndrome with closure of laser coloboms in 1-6 months after surgery decreased to 33.3 % (25.7 % and 40.9 % respectively).Conclusion. We recommended the patented differential approach for effective nontraumatic laser iridotomy in children with endogenous uveitis. In a thin iris single-stage YAG laser perforation should be performed in maximum bombe and multiple perforation in cases of multi-chamber bombe. In a dense thick iris or in cases of former iridotomy closure two-stage approach should be performed. First, circular coagulation should be done in the form of a ring or spot at the site of the planned coloboma. Second, YAG-laser perforation should be done in 10–14 days. The iris vessels topography, reflexogenic zones, and the peculiarities of the iris reactions to the lasers in children with endogenous uveitis should be considered when choosing a place for a coloboma. The use of thermal coagulating lasers should be limited, especially on thin irises. Active anti-inflammatory therapy and eye monitoring are necessary after laser surgery. The differential approach is safe, effective, and can be recommended for implementation in the practice of pediatric ophthalmology.
Combined Treatment of Post-Thrombotic Macular Edema with Navigation Laser Coagulation and Intravitreal Administration of Angiogenesis Inhibitors
Authors: Krylova I. A. , Fabrikantov O. L. 
Published: April 2023

At present about 16.4 million people in the world suffer from retinal venous occlusions (RVO). The pathophysiology of RVO includes changes in the vascular wall, blood flow, blood clotting. The key role in the pathogenesis of this group of diseases is played by ischemia and retinal hypoxia, leading to neovascularization. Macular edema (ME) is the most common complication of retinal vein occlusions. Optical coherence tomography-angiography (OCTA) is considered as an informative and highly sensitive method for diagnosing macular edema (ME) and ischemic zones in RVO. Intravitreal administration of glucocorticosteroids and/or angiogenesis inhibitors is the priority treatment method for macular edema in RVO. The combination of antiangiogenic therapy and laser treatment is promising. The navigation treatment technology is implemented under the conditions of the Navilas 577 system. The Navilas 577 laser navigation system is a laser coagulator with a tracking system and a fundus camera. The possibility of planning the operation, superimposing the results of OCTA on a fundus image makes the treatment faster, more accurate, and minimizes damage to healthy tissues.Purpose: to evaluate the results of target topographically oriented threshold laser coagulation in the treatment of post-thrombotic ME using theNavilas 577 laser navigation system following intravitreal administration of angiogenesis inhibitors.Materials and methods. There was performed a prospective study of the results of navigation laser treatment on the Navilas 577 device after intravitreal injections of angiogenesis inhibitors in 14 patients (14 eyes), aged 51 to 83 years, with macular edema up to 390 μm due to the branch central retinal vein occlusion. Laser treatment was performed within 2 weeks to 1 month following the last injection of angiogenesis inhibitors. The zones of ischemia in the macula were determined according to OCT-A data, imported into the Navilas 577 navigation system and superimposed on a color fundus image. Then the treatment was planned — the position of the future coagulates was marked.Results. In 3 months, there was a decrease in the height of edema from 366.5 (323;390) to 280 (270;300) μm, an increase in light sensitivity in the central retinal zone from 17 to 21.2 dB and an increase in visual acuity from 0.4 (0.3;0.5) to 0.5 (0.45;0.6).Conclusion. The combination of navigation retinal laser coagulation and angiogenesis inhibitors in the treatment of low post-thrombotic edema (less than 390 μm) gives good results; therefore, it can be justified and advisable in real clinical practice.
Evaluation of flow, Ph and solubility of a new calcium silicate-based sealer: A comparative in-vitro study
Authors: Choudhary Ashish , Kaul Rudra , Malik Azhar , Sharma Aditi , Gupta Ajay 
Published: April 2023

The physical properties of sealers were evaluated for flow, setting time, radiopacity, dimensional stability, PH change, and solubility. Thus, the aim of this study was to compare a new calcium silicate-based sealer (Ceraseal) with 2 well established root canal sealers (MTA Fillapex & AH Plus) based on their flow, alkalinity and solubility. Three already established root canal sealers (MTA Fillapex, Ceraseal & AH Plus) were assessed for flow, alkalinity and solubility among 40 samples. For flow evaluation and pH evaluation 15 samples each were used, and for solubility test 10 samples were used. Statistical analysis was performed using t test and Tukey parametric tests after evaluating the normality of data. The significance level was set at 5%.AH plus showed maximum flow among all the sealers followed by MTA fillapex and Ceraseal. It was found that maximum pH was seen among ceraseal root canal sealer at 72 hours. When MTA Fillapex and ceraseal were compared the results were not significant statistically, except at 72 hours. The maximum solubility was seen among ceraseal sealer followed by MTA Fillapex and AH Plus. The results were significant statistically. Ceraseal had acceptable flow and an alkaline pH while also having a greater solubility, which may be a sign of its bioactivity given the limits of this in vitro investigation.
The Determinants of Bank Stability: An Empirical Investigation in Southeast Asia
Authors: Niken Novita Sari  , Barianto Nurasri Sudarmawan  
Published: April 2023

ABSTRACT
This research aimed to examine the effect of institutional quality, financing growth, and earnings management on the stability of Islamic banks in Southeast Asia for the 2014-2021 period. The sampling technique used was purposive sampling and received 11 Islamic commercial banks from Brunei Darussalam, Indonesia, and Malaysia. Data sources were obtained from each bank’s financial statements and the World Bank’s statements. The analysis method used was panel data regression analysis with Eviews 12 software. The results showed that the quality of institutions and the growth of financing had a significant effect on the stability of banks proxied by the Z-Score. The quality of institutions has a positive influence, while the growth of financing has a negative effect on banks' stability. Furthermore, the variables of earnings management have no significant impact on the stability of the bank. This research was limited to a sample of countries in Southeast Asia, so it is expected to be a reference for improving the quality of institutions to support banking performance. The implications of this study are expected to be an evaluation for banks to pay more attention to their policies in financing expansion and improve the quality of financial statements to minimize earnings management practices whose existence does not affect bank stability.
Keywords: Bank stability, institutional quality, banking performance, financing

ABSTRAK
Penelitian ini bertujuan untuk menguji pengaruh kualitas institusi, pertumbuhan pembiayaan dan manajemen laba terhadap stabilitas bank syariah di Asia Tenggara periode 2014-2021. Teknik pengambilan sampel menggunakan metode purposive sampling dan diperoleh 11 bank umum syariah dari negara Brunei Darussalam, Indonesia dan Malaysia. Sumber data diperoleh dari laporan keuangan masing-masing perbankan dan laporan World Bank. Metode analisis yang digunakan ialah analisis regresi data panel dengan software Eviews 12. Hasil penelitian menunjukkan bahwa kualitas institusi dan pertumbuhan pembiayaan berpengaruh secara signifikan pada stabilitas bank yang diproksikan dengan Z-Score. Kualitas institusi memiliki pengaruh yang positif sedangkan pertumbuhan pembiayaan berpengaruh negatif pada stabilitas bank. Selanjutnya, variabel manajemen laba tidak berpengaruh secara signifikan pada stabilitas bank. Penelitian ini terbatas pada sampel negara di Asia Tenggara, sehingga diharapkan dapat menjadi referensi dalam meningkatkan kualitas institusi untuk menunjang kinerja perbankan. Implikasi dari penelitian ini diharapkan dapat menjadi evaluasi bagi perbankan untuk lebih memperhatikan kebijakannya dalam ekspansi pembiayaan dan meningkatkan kualitas laporan keuangan guna meminimalisir praktik manajemen laba yang keberadaanya tidak mempengaruhi stabilitas bank.
Kata Kunci: Stabilitas Bank, Kualitas Institusi, Kinerja Perbankan, Pembiayaan
THE IMPACT OF CONSUMING SALMON FISH (SALMO SALAR) ON DENTAL CALCIUM LEVELS IN MICE (MUS MUSCULUS)
Authors: Christiono Sandy , Salsabila Naila , Amalina Rizki , Anggarani Welly , Hutami Islamy Rahma 
Published: April 2023

ABSTRACTBackground: Pregnant women require calcium as a vital vitamin. Insufficient calcium intake during pregnancy can result in enamel hypoplasia and cavities in deciduous teeth. It can boost pregnant women's calcium intake with calcium-containing pill formulations and vitamin D; however, this has negative effects such as kidney stone issues. Salmon can be used as a substitute because it has no negative side effects and contains omega 3, which can enhance calcium absorption. Purpose: This study aimed to determine the effect of salmon (Salmo salar) consumption on calcium levels in the teeth of mice (Mus musculus). Method: This study used pregnant mice and a post-test-only control strategy. Pregnant mice were fed salmon combined with CMC (Carboxy Methyl Cellulose) and CMC (Carboxy Methyl Cellulose) alone as a control. The salmon dose administered is 2.17 mg/0.5 ml. Using atomic absorption spectrophotometry, mice dental calcium levels can be determined (AAS). Result: The findings of hypothesis testing with an unpaired t-test of 0.041 revealed a significant difference between the salmon-eating and CMC-consuming groups at p 0.05. (Carboxy Methyl Cellulose). Conclusion: Consuming salmon can significantly increase the calcium content of mouse teeth. Keywords: Dental calcium, Mice (Mus Musculus, Pregnant mice, Salmon (salmo nalar)
Effectiveness of STEM-Based Lectora Inspire Media to Improve Students’ HOTS in Physics Learning
Authors: Kurniawan Aziz , Tantri Irma Dwi , Fian Khafifatul 
Published: April 2023

This study aimed to determine the effectiveness of STEM-based lectora inspire media to improve the student’s higher order thinking skills (HOTS). This research design was Research and Development (RnD). This research referred to the ADDIE model that included Analysis, Design, Development, Implementation, and Evaluation. The data were gathered through questionnaires and tests. The questionnaire technique was used to test the feasibility of the material and media used. At the same time, the test instrument was used to determine the increase in students’ HOTS based on the final results after using the product. The results showed that the developed media was categorized as feasible to be used as a student learning media with an average score of 93.745% of material expert judgment and 87.485% of media expert judgment. The responses of science teachers and students as users were 91.66% and 87%. Both concluded that the learning media was efficient. Paired sample t-test resulted in a significance value of 0.000 < 0.005, and the N-Gains test yielded a value of 58%. Thus, it can be concluded that STEM-based Lectora Inspire Media can improve the student’s higher order thinking skills (HOTS).
Evaluation of clinical pharmacist-led medication review in patients referred to a hospital-based residential aged care support service
Authors: Chan June , Bolitho Richard , Hay Karen , Yong Faith 
Published: April 2023

Abstract
Background

Hospital-based Residential Aged-care Support Service (RaSS) teams typically consist of doctors and nurses who provide emergency and hospital substitutive care to residents of residential aged care facilities (RACF). While evidence supports the role of community pharmacist-led medication reviews in RACFs, there is limited literature evaluating the role of pharmacists integrated into aged care support teams. The purpose of this study was to analyse the effect of RaSS pharmacist-led medication reviews on polypharmacy, drug burden index, potentially inappropriate medications and potential prescribing omissions for residents living in RACFs.

Methods

Residents were referred to a Residential Aged-care Support Service pharmacist for medication review over a 12-month period. Medication-related problems and recommendations identified by the pharmacist were communicated to the resident’s general practitioner and RaSS medical practitioner for review. Residents’ medication histories were obtained at baseline and at one-month post-intervention. The number of medications prescribed to RACF residents, their associated drug burden indices, potentially inappropriate medications, and potential prescribing omissions identified at baseline and post-intervention were compared to evaluate the effects of RaSS pharmacist-led medication reviews.

Results

175 residents with a mean age of 84 years were referred to a hospital-based Residential Aged-care Support Service pharmacist for medication review. Median time to post-intervention evaluation was 29 days. The mean total number of medications prescribed were reduced from 18 medications at baseline to 17 medications post-intervention (p<0.001). The mean drug burden index score was reduced from 1.53 (at baseline) to 1.35 post-intervention (p<0.001). There were more residents that experienced a decrease in inappropriate medications (p<0.001) and prescribing omissions (p=0.008) compared to those that had an increase.

Conclusions

This study suggests that medication reviews performed by pharmacists embedded in hospital-based residential aged care support services may improve medication use and prescribing practices in aged care. Future research needs to be prioritised to corroborate this.
Tailoring Elastic Scattering of Relativistic Antiferromagnetic
Domain Walls for Collision-based Computing
Authors: Otxoa Ruben M. , Tatara Gen , Roy Pierre E. , Chubykalo-Fesenko Oksana 
Published: April 2023

Abstract
Soliton-based computing relies on their unique properties for transporting energy and emerging intact from head-on collisions. Magnetic domain walls are often referred to as solitons disregarding the strict mathematical definition requiring the above scattering property. Here we demonstrate the conditions of elastic and inelastic scattering for spinorbit torque-induced dynamics of relativistic domain walls on the technologically relevant Mn2Au antiferromagnetic material. We show that even domain walls with opposite winding numbers can experience elastic scattering and we present the corresponding phase
diagram as a function of the spin-orbit field strength and duration. The elastic collision requires minimum domain walls speed, which we explain assuming an attractive potential
created by domain wall pair. On the contrary, when the domain walls move at lower speeds, their collision is inelastic and results in a dispersing breather. Our findings will be
important for the development of soliton-based computing using antiferromagnetic spintronics and we discuss their prospects for building NOT and XOR gates.
Repurposing Drugs for COVID-19 by Graph Convolutional Network
Authors: Yue Rongting , Dutta Abhishek 
Published: April 2023

Abstract
Computational approaches for drug repurposing speed up the process of finding drugs for fast-spreading diseases such as COVID-19, which is challenging due to unknown disease mechanisms and pathogens. Here we present a graph learning-based pipeline to identify the potential drugs that are likely to intervene in COVID-19 virus infection using RNA-seq data and molecular interactions and features. We do so by detecting disease-related genes and pathways first, then constructing a heterogeneous graph model that integrates protein-protein interactions, drug-protein interaction and drug-target interactions, and finally applying graph convolutional network on the graph model to predict potential drug molecules. With this method, we predict 28 drugs that have the potential to bind with disease-related proteins. Molecular docking shows that 2 drugs, Flunisolide and Adapalene, have a high possibility to be used for COVID-19 by stably binding with the products of disease-related genes STAT1 and AKT1, respectively, which will be later confirmed by experiments. The proposed method applies to drug repurposing for any diseases with gene expression data, and it is expected to expand our understanding of novel disease mechanisms and select drug candidates for therapy design.
Characterizing the Social-Ecological System for Inland Freshwater Salinization using Fuzzy Cognitive Maps: Implications for Collective Management
Authors: Rippy Megan , Grant Stanley , Roston Benjamin , Berglund Emily , Aminpour Payam , Krauss Lauren , Bhide Shantanu , Schenk Todd , Rowles Kristin , Misra Shalini , Birkland Thomas , Kaushal Sujay 
Published: April 2023

Abstract
Current regulatory tools are not well suited to address freshwater salinization in urban areas and the conditions under which bottom-up management is likely to emerge remain unclear. We hypothesize that Ostrom’s social-ecological-systems (SES) framework can be used to explore how current understanding of salinization might foster or impede its collective management. Our study focuses on the Occoquan Reservoir, a critical urban water supply in Northern Virginia, U.S., and uses fuzzy cognitive maps (FCMs) to characterize stakeholder understanding of the SES that underpins salinization in the region. Hierarchical clustering of FCMs reveals four stakeholder groups with distinct views on the causes and consequences of salinization, and actions that could be taken to mitigate it, including technological, policy, and governance interventions and innovations. Similarities and differences across these four groups, and their degree of concordance with measured/modeled SES components, point to actions that could be taken to catalyze collective management of salinization in the region.
Construction of Interface-Engineered Coral-like Ni2P@CeO2 Hybrid Nanoarrays to Boost Electrocatalytic Hydrogen Evolution Performance in alkaline water/seawater electrolytes
Authors: Lyu Chaojie , Cheng Jiarun , Wang Huichao , Yang Yuquan , Wu Kaili , Song Peng , Lau Woon-Ming , Zheng Jinlong , Zhu Xixi , Yang Hui Ying 
Published: April 2023

Abstract
Fabricating a functional heterogeneous interface to enhance the catalytic performance is quite significant for developing high-efficient electrocatalysts. Herein, we designed a coral-like Ni2P@CeO2 hybrid nanoarrays on nickel foam via selective-phosphorization of Ni(OH)2@CeO2. Benefiting from CeO2 as the “electron pump”, it leads to electrons transfer from Ni2P to CeO2 side, and induces the electrons redistribution in interface boundary, thereby optimizing the H* adsorption free energy in HER process. As proposed, owing to the superior affinity to oxygen-containing species of CeO2, the H2O molecule will preferentially adsorb on CeO2 side, and easily decompose into OH* and H* with lower energy barrier. Subsequently, benefiting from the lower H* adsorption free energy of P sites, the generated H* will transfer to Ni2P side through spillover process. Contributing to the synergistic effect of double-active sites, the Ni2P@CeO2/NF electrode exhibits brilliant catalytic performance for HER with 62 mV to attain 10 mA/cm2 and exceptional durability over 100 h in 1 M KOH solution under ~ 100 mA/cm2. Meanwhile, attributing to the similar interface electrons redistribution effect, the precursor Ni(OH)2@CeO2/NF also displays excellent OER electrocatalytic performance, it only requires 229 mV to arrive 10 mA/cm2, even better than benchmark RuO2. Hence, the assembled Ni(OH)2@CeO2/NF||Ni2P@CeO2/NF system only needs 1.53 V to achieve 10 mA/cm2 in basic solution. Moreover, the electrolyzer also presents brilliant electrocatalytic activity and stability in natural seawater alkaline electrolyte with higher reserves on earth. This research offers a novel insight to enhance the catalytic properties of TMPs materials for hydrogen production.
Diagnosis by visualizing blood data -multiple myeloma
Authors: choi elisa 
Published: April 2023

Abstract
Multiple myeloma is the type of cancer that difficult to diagnosis early due to vague symptoms which can lead to misdiagnosis or create confusion with other diseases. When the symptoms are visible it may reach to advance cancer stage when even appropriate treatment is not left. This paper seeks and proposes a method for diagnosis of multiple myeloma through basic blood and urine tests by utilizing radar chart to increase readability and help to make rational decision making for patients and doctors. The radar chart is optimal way to visualizing numeric values. As a result of visualizing it as a graph, a clear visual and morphological difference was found compared to normal people.
Development of two elite water chestnut genotypes (Trapa spp.) and their molecular characterization using RAPD and ISSR markers
Authors: Jana Bakulranjan , Kornepati Anupama , Vaishna R.L. , Das Anup 
Published: April 2023

Abstract
Water chestnut (2n = 48) is an aquatic plant of Trapaceae family, the fruits of which are nutritious and have medicinal properties. By selecting from Green Spineless and Red Spineless Biotypes for high TSS and yield from natural population, we developed Improved Red Spineless (IRS) and Improved Green Spineless (IGS) genotypes and registered at N.B.P.G.R as IC 642169 and IC 642170, respectively. These two improved varieties were analyzed with the well-known local varieties using 10 RAPDs and 10 ISSR primers. A total of 78.0 polymorphic fragments with an average PIC of 0.32 and 0.16 and an average MI of 1.48 and 1.09 were produced by the RAPD and ISSR markers, respectively. The dendrogram analysis based on individual and combined RAPD and ISSR markers has demonstrated that the new improved varieties are molecularly distinct from the locally popular varieties. Among four genotypes, the unique gene sequences in 550 bp and 800 bp DNA ladders identified by AP-4 primer and 600 bp DNA ladders identified by AP-32 primer are only found in IRS genotype as dimorphic bands and single band, respectively. Similarly, in IGS water chestnut, DNA fragments AP30-1250, and ISSR23-1500 & ISSR23-1350 are only found as single bands and dimorphic bands, respectively.