bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Introduction to Mohammad-Taqi Bahār’s Sabkshenāsi: A Translation
Authors: Jabbari Alexander 
Published: May 2023

Abstract
Mohammad-Taqi Bahār’s 1942 textbook Sabkshenāsi (“Stylistics”) was a landmark text in modern Persian literary studies. It coined terms (like sabk-e Hendi or the “Indian style” of Persian poetry) and laid out a tripartite, geographical-temporal model for the history of Persian poetry which largely remain dominant today. Bahār’s articulation of a national canon of Iranian literature (comprising writings in various stages of the Persian language as well as Arabic) made Sabkshenāsi an important text not only for the nascent department of Persian literature at the University of Tehran for which it was written, but for twentieth-century Iranian nationalism in general. By combining traditional forms of knowledge with the methodologies pioneered by European Orientalists, it played an important role in modernizing Persian literary studies. The influential introduction to Sabkshenāsi is translated here into English in full for the first time, along with a preface explaining the work’s importance for Persian literary studies.
Explaining Rationalist Weak Conciliationism: A Challenge
Authors: Thurow Joshua C. 
Published: May 2023

Abstract
In his book, Disagreement, Deference, and Religious Commitment, John Pittard presents and critiques what he calls the “master argument for disagreement-motivated religious skepticism.” This argument purports to show, using only higher-order reasoning and facts about religious disagreement, that nobody’s religious outlook is justified (at least, nobody aware of the argument). The master argument presupposes that any attempt to vindicate one’s religious outlook must employ dispute-independent reasons. Pittard objects to this assumption and argues, instead, for rationalist weak conciliationism: the view that partisan justification can be had when (and only when) one has rational insight into the claim in question. In this paper, I raise a challenge for rationalist weak conciliationism; in short, it is difficult to explain why only rational insight provides partisan justification while maintaining that a wide range of beliefs, including religious beliefs, can be justified in a partisan way.
Putting the World in the Centre: a Different Future for Scotland’s Education
Authors: Biesta Gert 
Published: May 2023

Abstract
This paper provides a critical discussion of Putting Learners at the Centre: Towards a Future Vision for Scottish Education, which was published by the Scottish Government in 2022. After reconstructing the case made in the report for putting learners at the centre of Scottish education, I raise critical questions, both about the idea that learners should be at the centre of education and that it is their learning that education should focus on. I also argue why the United Nations Convention on the Rights of the Child is insufficient as a basis for education. I then present the case for an alternative view, which neither puts learners nor the curriculum at the centre, but sees the physical, natural, and social world as that which education should centre on. I show how this may provide a more meaningful and more educational future for education in Scotland and elsewhere.
Pharmacological characterization of the selective orexin-1 receptor antagonist JNJ-61393215 in healthy volunteers
Authors: Brooks S , Zuiker RGJA , Bleys C , Ziagkos D , Moyer JA , van Nueten L , Bonaventure P , Drevets WC , van Gerven JMA , Salvadore G , Jacobs GE 
Published: May 2023

Background: Up to 40% of patients suffering from anxiety disorders do not benefit from currently available pharmacological treatments. Overactivity of the orexin-1 receptor (OX1R) has been implicated in anxiety- and panic-related states. Aim & methods: We investigated the pharmacokinetics and characterized the pharmacodynamic (PD) profile of the OX1R antagonist JNJ-61393215 using a battery of central nervous system assessments investigating relevant functional domains such as alertness, attention, (visuo)motor coordination, balance, subjective effects and resting-state electroencephalography in a single ascending dose placebo-controlled study in doses from 1 to 90 mg inclusive, assessing PD up to 10 h after dosing, safety and pharmacokinetic in 48 healthy male subjects. Results: Average time to maximal plasma concentration ( Tmax) ranged between 1.0 and 2.25 h; average half-life ranged from 13.6 to 24.6 h and average maximum plasma concentration ranged from 1.4 to 136.8 ng/mL in the 1 and 90 mg groups, respectively. JNJ-61393215 did not demonstrate any statistically significant or clinically meaningful effects on any PD endpoint at any dose investigated at Tmax nor over the total period up to 10 h post-dose and was well tolerated. The reported somnolence rate was 16.7% (which was attributable to the cohorts receiving 6 mg and higher doses) compared to 12.5% in placebo. Conclusion: This observation is in line with our knowledge about the OX1R in preclinical studies, where only inconsistent and non-dose-dependent changes in electroencephalography or other behavioural measures were observed under non-challenged conditions, potentially exemplifying the need for a challenged subject.
Questionnaire and structural imaging data accurately predict headache improvement in patients with acute post-traumatic headache attributed to mild traumatic brain injury
Authors: Mao Lingchao , Li Jing , Schwedt Todd J , Berisha Visar , Nikjou Devin , Wu Teresa , Dumkrieger Gina M , Ross Katherine B , Chong Catherine D 
Published: May 2023

Background Our prior work demonstrated that questionnaires assessing psychosocial symptoms have utility for predicting improvement in patients with acute post-traumatic headache following mild traumatic brain injury. In this cohort study, we aimed to determine whether prediction accuracy can be refined by adding structural magnetic resonance imaging (MRI) brain measures to the model. Methods Adults with acute post-traumatic headache (enrolled 0–59 days post-mild traumatic brain injury) underwent T1-weighted brain MRI and completed three questionnaires (Sports Concussion Assessment Tool, Pain Catastrophizing Scale, and the Trait Anxiety Inventory Scale). Individuals with post-traumatic headache completed an electronic headache diary allowing for determination of headache improvement at three- and at six-month follow-up. Questionnaire and MRI measures were used to train prediction models of headache improvement and headache trajectory. Results Forty-three patients with post-traumatic headache (mean age = 43.0, SD = 12.4; 27 females/16 males) and 61 healthy controls were enrolled (mean age = 39.1, SD = 12.8; 39 females/22 males). The best model achieved cross-validation Area Under the Curve of 0.801 and 0.805 for predicting headache improvement at three and at six months. The top contributing MRI features for the prediction included curvature and thickness of superior, middle, and inferior temporal, fusiform, inferior parietal, and lateral occipital regions. Patients with post-traumatic headache who did not improve by three months had less thickness and higher curvature measures and notably greater baseline differences in brain structure vs. healthy controls (thickness: p < 0.001, curvature: p = 0.012) than those who had headache improvement. Conclusions A model including clinical questionnaire data and measures of brain structure accurately predicted headache improvement in patients with post-traumatic headache and achieved improvement compared to a model developed using questionnaire data alone.
Three dimensional finite element analysis of biomechanics of osteotomy ends with three different fixation methods after hallux valgus minimally invasive osteotomy
Authors: Xie Qiang , Li Xiaodong , Wang Pei 
Published: May 2023

Purpose Biomechanical study of fixation methods post hallux valgus minimally invasive osteotomy using finite element technology hasn’t been reported. This study aimed to compare maximum displacement and stress distribution of osteotomy ends after minimally invasive osteotomy fixed by bandage, Kirschner wire, Herbert screw. Methods Foot CT images of a patient with mild-moderate hallux valgus were collected. Three-dimensional finite element model of hallux valgus was established through CT image. This study simulated bandage, Kirschner wire and Herbert screw fixation, and analyzed maximum displacement and stress distribution of osteotomy ends in plantar flexion position of foot after fixation. Results Maximum equivalent stress of osteotomy end fixed with bandage, Kirschner wire, Herbert screw was 7.8615, 14.253, 8.3156 MPa, respectively. Total displacement of osteotomy end fixed by bandage, Kirschner wire, Herbert screw was 0.26,896, 0.022,779, 0.029,195 mm, respectively. Maximum stress of Kirschner wire and Herbert screw near osteotomy end was 154.7 and 46.404 MPa, respectively. Fixation strength and stability of Kirschner wire and Herber screw were better than bandage. Kirschner wire had stress concentration phenomenon, with potential fracture risk. Stress of Herbert screw was evenly distributed around osteotomy end, and there was a certain stress concentration, playing an important role in maintaining fracture end stability. Conclusions Herbert screw showed good fixation strength and stability, and stress distribution was uniform, which can well maintain stability of minimally invasive osteotomy ends. Findings of this study would provide a theoretical basis for selection of fixation methods after clinical minimally invasive osteotomy for hallux valgus.
Ocular severe involvement in oculofaciocardiodental syndrome: Description of a case series
Authors: Moleiro Ana Filipa , Oliveira Joana Santos , Grangeia Ana , Faria Pedro , Falcão-Reis Fernando , Magalhães Augusto , Silva Sérgio Estrela 
Published: May 2023

Background Oculofaciocardiodental (OFCD) syndrome is a rare genetic disorder affecting ocular, facial, dental, and cardiac systems, being an X-linked condition caused by pathogenic variants in the BCL-6 corepressor gene ( BCOR). We report a case series of three female patients with OFCD syndrome with severe glaucoma. Results Three female patients with OFCD syndrome with different variants involving BCOR gene, in heterozygosity: a seven-years-old girl with an insertion (c.2037_2038dupCT), a nine years-old girl with a microdeletion in the X (p21.2-p11.4)) spanning the BCOR gene; and a 25 years-old female with a deletion (c.3858_3859del). Systemic involvement is variable among patients ranging from one patient mainly with ocular and dental involvement to one with associated intra-auricular and intra-ventricular defects. All the patients presented with congenital cataracts diagnosed in the first days of life. Cataract surgery was performed without incidents between 6 and 16 weeks of age in all the patients. Postoperatively, the three patients developed ocular hypertension and glaucoma with the need for surgical interventions, including trabeculectomy, Ahmed valve implantation, and cyclophotocoagulation. Conclusion OFCD syndrome characterizes by a severe ocular involvement with glaucoma as a characteristic feature. Ocular hypertension after cataract surgery in these patients is challenging, almost always needing surgery during childhood. Therefore, we consider BCOR disruption may predispose to a higher incidence of glaucoma due to its aggressiveness and early onset on our case series. The awareness of these complications is crucial to an adequate follow-up of the patients.
Associations of gross motor skills with self-regulation and executive function in preschool-aged children
Authors: Veldman Sanne LC , Hammersley Megan L , Howard Steven J , Stanley Rebecca M , Okely Anthony D , Jones Rachel A 
Published: May 2023

This study aimed to examine associations between gross motor skills and executive functions (EF) in a large sample of Australian preschool-aged children. Of 566 children (mean age = 3.2 ± 0.4 years, 51.2% girls), locomotor, object control, and total skill competence were significantly associated with visual spatial working memory and inhibition ( p < 0.05). Total skill competence was associated with shifting and locomotor skills were significantly associated with self-regulation ( p < 0.05). Static balance was significantly associated with inhibition and shifting ( p < 0.05). In boys, an association between object control skills and visual spatial working memory was observed. In girls, an association between static balance and visual spatial working memory, phonological working memory, and shifting was observed. The identification of significant associations between gross motor skills and different EFs is an important contribution to the growing evidence on the relationship between motor skills and EFs in early childhood.
Preoperative Dehydration Increases the Risk of Extended Length of Hospital Stay Following Total Ankle Arthroplasty
Authors: Quan Theodore , Magruder Matthew , Chen Frank R. , Tabaie Sean , Best Matthew J. , Aiyer Amiethab 
Published: May 2023

Introduction The effects of preoperative dehydration on outcomes following total ankle arthroplasty (TAA) remain unknown. Therefore, the purpose of this study is to evaluate the association between dehydration and postoperative complications for patients undergoing TAA. Methods Patients undergoing TAA from 2007 to 2019 were identified in the National Surgical Quality Improvement Program (NSQIP) database. A preoperative serum blood urea nitrogen/creatinine (BUN/Cr) greater than 20 was used to define preoperative dehydration. Patients were stratified into 2 cohorts: patients who were dehydrated (BUN/Cr > 20) and patients without dehydration (BUN/Cr ≤ 20). In this analysis, various postoperative outcomes were assessed with bivariate and multivariate analyses. Results In total, 1033 patients underwent TAA and had their serum BUN and Cr values recorded. For both BUN and Cr, the patients in this study had their serum values recorded a mean of 15 days before their surgery. A total of 588 patients (56.9%) did not have dehydration preoperatively and 445 patients (43.1%) were dehydrated. Following adjustment on multivariate analysis, an increased risk of extended length of hospital stay (odds ratio [OR] = 1.457; p = 0.024) was seen in the dehydrated group compared with those who were noted to be well hydrated. Conclusion As fluid intake is one modifiable preoperative variable that can be easily monitored during elective procedures, it is important for physicians to be aware of patients who are dehydrated and adjust their fluids appropriately to optimize postoperative outcomes. Levels of Evidence: Level III: Retrospective cohort study
Feasibility, acceptance and factors related to the implementation of telemedicine in rural areas: A scoping review protocol
Authors: Aufa Badra Al , Nurfikri Ari , Mardiati Wiwiet , Sancoko Sancoko , Yuliyanto Heri , Nurmansyah Mochamad Iqbal , Arumsari Imas , Koire Ibrahim Isa 
Published: May 2023

Background Telemedicine is a quickly developing service that offers more people the access to effective and high-quality healthcare. Societies residing in rural places tend to travel long distances to receive health care, usually have limited access to health care and/or postpone getting health care until a health emergency occurs. However, for telemedicine services to be accessible, a number of prerequisites including the availability of cutting-edge technology and equipment in rural areas must be present. Objective This scoping review aims to collect all available data on the viability, acceptability, challenges and facilitators of telemedicine in rural areas. Methods PubMed, Scopus and Medical collection of ProQuest are the databases chosen for an electronic search of the literature. Identification of the title and abstract will be followed by an evaluation of the paper's accuracy and eligibility in a two-fold mode; whereas the identification of papers will be openly and completely described using the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) flowchart. Conclusion This scoping review would be among the first to offer a thorough evaluation of issues related to the viability, acceptance and implementation of telemedicine in rural areas. In order to improve the conditions of supply, demand and other circumstances relevant to the implementation of telemedicine, the results would be helpful in providing direction and recommendations for future developments in the usage of telemedicine, particularly in rural areas.
Neurodata Tracker: Software for computational assessment of hand motor skills based on optical motion capture in a virtual environment
Authors: López David , Casado-Fernández Laura , Fernández Fernando , Fuentes Blanca , Larraga-García Blanca , Rodríguez-Pardo Jorge , Hernández David , Alonso Elisa , Díez-Tejedor Exuperio , Gutiérrez Álvaro , Alonso de Leciñana María 
Published: May 2023

Objectives Deficits affecting hand motor skills negatively impact the quality of life of patients. The NeuroData Tracker platform has been developed for the objective and precise evaluation of hand motor deficits. We describe the design and development of the platform and analyse the technological feasibility and usability in a relevant clinical setting. Methods A software application was developed in Unity (C#) to obtain kinematic data from hand movement tracking by a portable device with two cameras and three infrared sensors (leap motion®). Four exercises were implemented: (a) wrist flexion-extension (b) finger-grip opening-closing (c) finger spread (d) fist opening-closing. The most representative kinematic parameters were selected for each exercise. A script in Python was integrated in the platform to transform real-time kinematic data into relevant information for the clinician. The application was tested in a pilot study comparing the data provided by the tool from ten healthy subjects without any motor impairment and ten patients diagnosed with a stroke with mild to moderate hand motor deficit. Results The NeuroData Tracker allowed the parameterization of kinematics of hand movement and the issuance of a report with the results. The comparison of the data obtained suggests the feasibility of the tool for detecting differences between patients and healthy subjects. Conclusions This new platform based on optical motion capturing provides objective measurement of hand movement allowing quantification of motor deficits. These findings require further validation of the tool in larger trials to verify its usefulness in the clinical setting.
Development of the information quality scale for health information supply chain type 2 diabetes mellitus management using exploratory factor analysis
Authors: Karimah Rinda Nurul , Kusnanto Hari , Lazuardi Lutfan 
Published: May 2023

Background: Research on the quality scale of the healthcare supply chain is still limited. This study aimed to assess the information quality of the supply chain model with a focus on construct validity. Studies related to information quality measurement generally focus on measuring the dimensions of the completeness of medical records and consumer perspectives. We intended to assess the scale based on doctors needed as care coordinators on type 2 diabetes mellitus or the Non-Insulin-Dependent-Diabetes-Mellitus (NIDDM) program in primary healthcare. Methods: Sixty-four primary healthcare doctors with an age range of 24–51 years were involved in this research. The scale obtained was formed from the assessment of the point of view of a panel of experts through the content validity index (CVI). The exploratory factor analysis (EFA) method was used to explore the scale of information quality in the information supply chain model for the NIDDM chronic disease management program. Result: The data analysis results indicated three main factors that affected the quality of the information supply chain model of NIDDM, namely accessibility, safety, and efficiency of information related to NIDDM. The results of the validity and reliability of the data showed that the scale used in this research was valid and reliable with a Cronbach alpha coefficient of 0.861. Conclusion: The scale developed in this research could be used to explore the quality of the information supply chain of NIDDM management in primary healthcare. Each item on the scale could explain the variables according to their respective groups.
Heterogeneity of treatment effects by risk in pulmonary arterial hypertension
Authors: Pan Hao-Min , McClelland Robyn L. , Moutchia Jude , Appleby Dina H. , Fritz Jason S. , Holmes John H. , Minhas Jasleen , Palevsky Harold I. , Urbanowicz Ryan J. , Kawut Steven M. , Al-Naamani Nadine 
Published: May 2023

BackgroundIt is currently unknown if disease severity modifies response to therapy in pulmonary arterial hypertension (PAH). We aimed to explore if disease severity, as defined by established risk-prediction algorithms, modified response to therapy in randomised clinical trials in PAH.MethodsWe performed a meta-analysis using individual participant data from 18 randomised clinical trials of therapy for PAH submitted to the United States Food and Drug Administration to determine if predicted risk of 1-year mortality at randomisation modified the treatment effect on three outcomes: change in 6-min walk distance (6MWD), clinical worsening at 12 weeks and time to clinical worsening.ResultsOf 6561 patients with a baseline US Registry to Evaluate Early and Long-Term PAH Disease Management (REVEAL 2.0) score, we found that individuals with higher baseline risk had higher probabilities of clinical worsening but no difference in change in 6MWD. We detected a significant interaction of REVEAL 2.0 risk and treatment assignment on change in 6MWD. For every 3-point increase in REVEAL 2.0 score, there was a 12.49 m (95% CI 5.86–19.12 m; p=0.001) greater treatment effect in change in 6MWD. We did not detect a significant risk by treatment interaction on clinical worsening with most of the risk-prediction algorithms.ConclusionsWe found that predicted risk of 1-year mortality in PAH modified treatment effect as measured by 6MWD, but not clinical worsening. Our findings highlight the importance of identifying sources of treatment heterogeneity by predicted risk to tailor studies to patients most likely to have the greatest treatment response.
Pre-excited atrial fibrillation revealed at a very delayed age: case report
Authors: Diallo Thierno Hamidou , Faraj Raid , Hilal Safae , Lahraoui Myriam , Kisra Oualid , Benmessaoud Fatima-Azzahra , Doghmi Nawal , Fellat Ibtissam , Cherti Mohamed 
Published: May 2023

Abstract
Background
Wolff-Parkinson-White (WPW) syndrome is a condition characterized by the persistence of an accessory pathway responsible for ventricular pre-excitation that can lead to symptomatic and potentially severe arrhythmias. Coexistence with atrial fibrillation is well known and not uncommon, exposing to potential degenerescence into ventricular fibrillation when atrial impulses are transmitted along the accessory pathway. WPW syndrome is most prevalent in younger patients and cases revealed after an advanced age have rarely been described in the literature.

Case presentation
Here, we report a case of atrial pre-excitation first diagnosed at the age of 72 years that required external electrical cardioversion with a favorable outcome. The diagnosis was based on clinical and electrographic findings.

Conclusions
WPW syndrome is a relatively rare cardiac disorder that can be a cause of sudden death, especially when combined with atrial fibrillation. Therefore, cardiologists have to consider this diagnosis in patients presenting clinical signs of arrhythmia with an electrical pattern of WPW.