bluuebunny/crossref_metadata_2025_split huggingface dataset:
A statistically stationary minimal flow unit for self-similar Rayleigh–Taylor turbulence in the mode-coupling limit
Authors: Goh Chian Yeh , Blanquart Guillaume 
Published: January 2025

We propose a computational framework for simulating the self-similar regime of turbulent Rayleigh–Taylor (RT) mixing layers in a statistically stationary manner. By leveraging the anticipated self-similar behaviour of RT mixing layers, a transformation of the vertical coordinate and velocities is applied to the Navier–Stokes equations (NSE), yielding modified equations that resemble the original NSE but include two sets of additional terms. Solving these equations, a statistically stationary RT (SRT) flow is achieved. Unlike temporally growing Rayleigh–Taylor (TRT) flow, SRT flow is independent of initial conditions and can be simulated over infinite simulation time without escalating resolution requirements, hence guaranteeing statistical convergence. Direct numerical simulations (DNS) are performed at an Atwood number of 0.5 and unity Schmidt number. By varying the ratio of the mixing layer height to the domain width, a minimal flow unit of aspect ratio 1.5 is found to approximate TRT turbulence in the self-similar mode-coupling regime. The SRT minimal flow unit has one-sixteenth the number of grid points required by the equivalent TRT simulation of the same Reynolds number and grid resolution. The resultant flow corresponds to a theoretical limit where self-similarity is observed in all fields and across the entire spatial domain – a late-time state that existing experiments and DNS of TRT flow have difficulties attaining. Simulations of the SRT minimal flow unit span TRT-equivalent Reynolds numbers (based on mixing layer height) ranging from 500 to 10 800. The SRT results are validated against TRT data from this study as well as from Cabot & Cook (Nat. Phys., vol. 2, 2006, pp. 562–568).
Literally ‘a jerk’: an experimental investigation of expressives in predicative position
Authors: Domaneschi Filippo , Cepollaro Bianca , Stojanovic Isidora 
Published: January 2025

Abstract
The semantic literature on negative expressive terms, such as ‘bastard’ and ‘jerk’, converges on two assumptions. First, the content associated with expressives is attitudinal; more precisely, it amounts to the condition that the agent (typically the speaker) has a negative attitude toward the target (that is, the person referred to with the expressive). Second, the use of such terms is felicitous as long as this condition is satisfied, regardless of whether this information is in the contextual background or not. This assumption has been challenged by Cepollaro, Domaneschi and Stojanovic (2021, Synthese), whose experimental studies show that negative expressives impose constraints on the context, contrary to what had been taken for granted in the literature. In line with their work, our goal is to investigate the first assumption on empirical grounds. Our studies show that when person A calls person B ‘a jerk’, participants prefer the target-oriented interpretation (that B must have done something bad) to the attitudinal agent-oriented interpretation (that A has a negative attitude toward B). Additionally, our studies replicate the main results from Cepollaro, Domaneschi and Stojanovic, 2021, Synthese), as well as reveal some unexpected asymmetries between positive and negative evaluative terms, which were used as control items.
“Talking heads” in Portuguese sign and spoken languages
Authors: Cruz Marisa , Frota Sónia 
Published: January 2025

Abstract
Head and eyebrow movements have been reported as question markers in both spoken (e.g. Swerts & Krahmer, 2004) and sign languages (e.g., Zeshan, 2004). However, the relative weight of these visual cues in conveying prosodic meaning remains unexplored. This study examines, through a kinematic analysis, if (and how) the amplitude of head falling movements varies in statements versus questions, both in Portuguese Sign Language (LGP) and in the spoken modality of European Portuguese. The results show that the head falling movement plays a key role in conveying interrogativity in Portuguese, in varying degrees. In LGP, the head amplitude is larger than in the spoken modality, and the shape of the head movement varies across sentence types, thus showing the primary role of this visual cue in LGP prosodic grammar. In spoken Portuguese, although the head amplitude also differs between sentence types, the shape of the movement over time is always the same (falling), thus pointing to a secondary/complementary role in spoken Portuguese.
These findings not only contribute to the knowledge of the prosodic grammar of spoken and sign languages, but also challenge traditional language processing models, mostly focused on verbal language.
A model of network redistributive pressure
Authors: Di Falco Salvatore , Feri Francesco , Pin Paolo 
Published: January 2025

Abstract
In this paper, we propose a network model to explain the implications of the pressure to share resources. Individuals use the network to establish social interactions that allow them to increase their income. They also use the network as a safety and to ask for assistance in case of need. The network is therefore a system characterized by social pressure to share and redistribute surplus of resources among members. The main result is that the potential redistributive pressure from other network members causes individuals to behave inefficiently. The number of social interactions used to employ workers displays a non-monotonic pattern with respect to the number of neighbors (degree): it increases for intermediate degree and decreases for high degree. Respect to a benchmark case without social pressure, individuals with few (many) network members interact more (less). Finally, we show that these predictions are consistent with the results obtained in a set of field experiments run in rural Tanzania.
Low-frequency turnover star-forming galaxies I: Radio continuum observations and global properties
Authors: Grundy Joe Arthur , Seymour Nicholas , Wong O. Ivy , Lee-Waddell Karen , Galvin Timothy James , Cluver Michelle 
Published: January 2025

Abstract
There is growing evidence that the broadband radio spectral energy distributions (SEDs) of star-forming galaxies (SFGs) contain a wealth of complex physics. In this paper we aim to determine the physical emission and loss processes causing radio SED curvature and steepening to see what observed global astrophysical properties, if any, are correlated with radio SED complexity. To do this, we have acquired radio continuum data between 70 MHz and 17 GHz for a sample of 19 southern local (

$z \lt 0.04$

) SFGs. Of this sample 11 are selected to contain low-frequency (

$ \lt $

300 MHz) turnovers (LFTOs) in their SEDs and eight are control galaxies with similar global properties. We model the radio SEDs for our sample using a Bayesian framework whereby radio emission (synchrotron and free-free) and absorption or loss processes are included modularly. We find that without the inclusion of higher frequency data (

$ \gt $

17 GHz) single synchrotron power-law based models are always preferred for our sample; however, additional processes including free-free absorption (FFA) and synchrotron losses are often required to accurately model radio SED complexity in SFGs. The fitted synchrotron spectral indices range from

$-0.45$

to

$-1.07$

and are strongly anticorrelated with stellar mass suggesting that synchrotron losses are the dominant mechanism acting to steepen the spectral index in larger/more massive nearby SFGs. We find that LFTOs in the radio SED are independent from the inclination of SFGs; however, higher inclination galaxies tend to have steeper fitted spectral indices indicating losses to diffusion of cosmic ray electrons into the galactic halo. Four of five of the merging systems in our SFG sample have elevated specific star formation rates and flatter fitted spectral indices with unconstrained LFTOs. Lastly, we find no significant separation in global properties between SFGs with or without modelled LFTOs. Overall these results suggest that LFTOs are likely caused by a combination of FFA and ionisation losses in individual recent starburst regions with specific orientations and interstellar medium properties that, when averaged over the entire galaxy, do not correlate with global astrophysical properties.
Supernova remnant candidates identified using MWA Galactic Plane Monitoring over
$285^{\circ} \lt l \lt 70^{\circ}$
and
$|b| \lt 16^{\circ}$
Authors: Mantovanini Silvia , Hurley-Walker Natasha , Anderson Gemma 
Published: January 2025

Abstract
Observations of Galactic supernova remnants (SNRs) are crucial to understanding supernova explosion mechanisms and their impact on our Galaxy’s evolution. SNRs are usually identified by searching for extended, circular structures in all-sky surveys. However, the resolution and sensitivity of any given survey results in selection biases related to the brightness and angular scale of a subset of the total SNR population. As a result, we have only identified 1/3 of the expected number of SNRs in our Galaxy. We used data collected by the Murchison Widefield Array (MWA) to perform a visual search for SNR candidates over

$ 285^{\circ} \lt l \lt 70^{\circ}$

and

$|b| \lt 16^{\circ}$

. We then used the Widefield Infrared Survey Explorer to eliminate likely Hii regions from our SNR candidate sample. By exploiting the resolution and sensitivity of MWA data, we have successfully detected 10 new candidates using our proposed method. In addition, our method has also enabled us to detect and verify 10 previously known but unconfirmed candidates. The 20 SNR candidates described in the paper will increase the known SNR population in the Galaxy by 7%.
Abiotic niche partitioning among congeneric species in an Atlantic forest fragment
Authors: Dantas Thais A. Vitoriano , Dantas Anderson , Silva Jackson dos Santos , Ribeiro-Neto José Domingos 
Published: January 2025

Abstract
Understanding the processes that allow phylogenetically related plant species coexist is important to understand the ecological and evolutionary processes that structure biological communities. In this study, we investigated how the species Erythroxylum simonis, Erythroxylum pauferrense and Erythroxylum citrifolium share ecological niche dimensions according to the abiotic characteristics of their environments of occurrence. To this end, in ten pre-established plots in an Atlantic Forest remnant in northeastern Brazil, we carried out a population survey of the three species and characterised their abiotic niche by measuring light availability, humidity and the physical–chemical properties of the soil. We used generalised linear models to test whether abiotic variables influence species abundance. Our results indicate that the three species coexist along the different environmental gradients, with some level of niche overlap. The species E. simonis is the best competitor, showing generalist behaviour and the highest abundance in all environmental gradients. We emphasise that the adult populations of the species have adapted to various environmental and ecological challenges. Thus, the results reported are influenced by their ability to perform well in terms of physiology, growth and survival in their early-life stages.
The global burden of cancer attributable to dietary factors from 1990 to 2019
Authors: Xie Jiping , Zhao Jing 
Published: January 2025

Abstract

Objective:
To analyze the global cancer burden associated with dietary factors across 204 countries and regions from 1990 to 2019.

Design:
A population-based study

Setting:
Global Burden of Disease Study

Participants:
Using data from the 2019 global burden of disease, we calculated Population Attributable Fractions (PAFs), death and disability-adjusted life years (DALYs). A comparative risk assessment framework was employed, along with estimated annual percentage changes (EAPCs).

Results:
In 2019, approximately 6.01% of cancer mortality and 5.50% of DALY rates can be attributed to dietary risk factors, particularly low intake of whole grains, milk, and fruits and vegetables. The High Socio-Demographic Index (SDI) region had the highest cancer mortality and DALY PAFs, mainly due to high consumption of red and processed meats, while the Low SDI region showed the highest PAFs from low fruit and vegetable consumption. In 2019, the High-middle SDI region had the highest age-standardized death rate (ASDR) and DALY rate attributable to dietary factors. Among geographic regions, Southern Latin America had the highest ASDR, and Central Europe had the highest age-standardized DALY rate. At the country level, Mongolia exhibited the highest rates for both ASDR and DALYs attributable to dietary risks. From 1990 to 2019, the largest increase in ASDR was observed in Western Sub-Saharan Africa, with Bulgaria showing the largest country-specific increase. Similarly, the largest increase in the age-standardized DALY rate was seen in Western Sub-Saharan Africa, with Lesotho experiencing the highest increase at the country level.

Conclusions:
Our findings underscored the importance of increasing the consumption of whole grains, milk, and calcium, which can inform global dietary guidelines and cancer prevention strategies.
Departmental practice on informed consent in radiotherapy departments: a UK evaluation
Authors: Orr Marie , Rosbottom Keeley 
Published: January 2025

Abstract

Introduction:
Valid and informed consent in healthcare is an ethical and legal requirement. This evaluation reports the practices within UK radiotherapy departments surrounding consent processes and therapeutic radiographer (TR) education. This article focuses on those patients who are considered to lack the capacity to consent.

Method:
This service evaluation adopted a qualitative research design. Seventy-six radiotherapy department managers were sent the online survey: containing a combination of open, closed and free text questions relating to consent practices. Descriptive analysis using Microsoft Excel was performed; additional correlation analysis was attempted with Fisher’s exact test using Statistical Package for the Social Sciences.

Results:
TRs from 39 radiotherapy departments (51%) completed the survey. Analysis of results demonstrated obtaining written consent before radiotherapy treatment was completed in all departments. Assessment methods used to determine capacity to consent varied across the departments. Responses identified 37 departments employ a different consent form for those considered to lack capacity. Thirty-eight departments have a policy surrounding consent; 16 departments reported no formal TR education in consent. Of the remaining 22 departments, 13 departments included lack of capacity within their education package.

Conclusion:
To ensure best practice throughout the UK, is it recommended that radiotherapy departments review their consent processes to ensure they are in the best interests of the patient. It is recommended that TRs are familiar with their regulatory body standards and the ethical and legal issues surrounding consent; all departments should consider capacity and those considered to lack capacity within their education and training framework.
Associations among rearing environment and the infant gut microbiome with early-life neurodevelopment and cognitive development in a nonhuman primate model (Macaca mulatta)
Authors: Daiy Katherine , Wiley Kyle , Allen Jacob , Bailey Michael T. , Dettmer Amanda M. 
Published: January 2025

Abstract
Early gut microbiome development may impact brain and behavioral development. Using a nonhuman primate model (Macaca mulatta), we investigated the association between social environments and the gut microbiome on infant neurodevelopment and cognitive function. Infant rhesus monkeys (n = 33) were either mother-peer-reared (MPR) or nursery-reared (NR). Neurodevelopmental outcomes, namely emotional responsivity, visual orientation, and motor maturity, were assessed with the Primate Neonatal Neurobehavioral Assessment (PNNA) at 14–30 days. Cognitive development was assessed through tasks evaluating infant reward association, cognitive flexibility, and impulsivity at 6–8 months. The fecal microbiome was quantified from rectal swabs via 16S rRNA sequencing. Factor analysis was used to identify “co-abundance factors” describing patterns of microbial composition. We used multiple linear regressions with AIC Model Selection and differential abundance analysis (MaAsLin2) to evaluate relationships between co-abundance factors, microbiome diversity, and neuro-/cognitive development outcomes. At 30 days of age, a gut microbiome co-abundance factor, or pattern, with high Prevotella and Lactobacillus (β = −0.88, p = 0.04, AIC Weight = 68%) and gut microbiome alpha diversity as measured by Shannon diversity (β = −1.33, p = 0.02, AIC Weight = 80%) were both negatively associated with infant emotional responsivity. At 30 days of age, being NR was also associated with lower emotional responsivity (Factor 1 model: β = −3.13, p < 0.01; Shannon diversity model: β = −3.77, p < 0.01). The infant gut microbiome, along with early-rearing environments, may shape domains of neuro-/cognitive development related to temperament.
Maternal exposure to purified versus grain-based diet during early lactation in mice affects offspring growth and reduces responsivity to Western-style diet challenge in adulthood
Authors: Rakhshandehroo M. , Harvey L. , de Bruin A. , Timmer E. , Lohr J. , Tims S. , Schipper L. 
Published: January 2025

Abstract
The nutritional environment during fetal and early postnatal life has a long-term impact on growth, development, and metabolic health of the offspring, a process termed “nutritional programming.” Rodent models studying programming effects of nutritional interventions use either purified or grain-based rodent diets as background diets. However, the impact of these diets on phenotypic outcomes in these models has not been comprehensively investigated. We used a previously validated (C57BL/6J) mouse model to investigate the effects of infant milk formula (IMF) interventions on nutritional programming. Specifically, we investigated the effects of maternal diet type (i.e., grain-based vs purified) during early lactation and prior to the intervention on offspring growth, metabolic phenotype, and gut microbiota profile. Maternal exposure to purified diet led to an increased post-weaning growth velocity in the offspring and reduced adult diet-induced obesity. Further, maternal exposure to purified diet reduced the offspring gut microbiota diversity and modified its composition post-weaning. These data not only reinforce the notion that maternal nutrition significantly influences the programming of offspring vulnerability to an obesogenic diet in adulthood but emphasizes the importance of careful selection of standard background diet type when designing any preclinical study with (early life) nutritional interventions.
Physicochemical Properties and Bioreactivity of Sub‐10 μm Geogenic Particles: Comparison of Volcanic Ash and Desert Dust
Authors: Tomašek Ines , Eychenne Julia , Damby David E. , Hornby Adrian J. , Romanias Manolis N. , Moune Severine , Uzu Gaëlle , Schiavi Federica , Dole Maeva , Gardès Emmanuel , Laumonier Mickael , Gorce Clara , Minet‐Quinard Régine , Durif Julie , Belville Corinne , Traoré Ousmane , Blanchon Loïc , Sapin Vincent 
Published: January 2025

AbstractExposure to ambient particulate matter (PM) with an aerodynamic diameter of <10 μm (PM10) is a well‐established health hazard. There is increasing evidence that geogenic (Earth‐derived) particles can induce adverse biological effects upon inhalation, though there is high variability in particle bioreactivity that is associated with particle source and physicochemical properties. In this study, we investigated physicochemical properties and biological reactivity of volcanic ash from the April 2021 eruption of La Soufrière volcano, St. Vincent, and two desert dust samples: a standardized test dust from Arizona and an aeolian Gobi Desert dust sampled in China. We determined particle size, morphology, mineralogy, surface texture and chemistry in sub‐10 μm material to investigate associations between particle physicochemical properties and observed bioreactivity. We assessed cellular responses (cytotoxic and pro‐inflammatory effects) to acute particle exposures (24 hr) in monocultures at the air‐liquid interface using two types of cells of the human airways: BEAS‐2B bronchial epithelial cells and A549 alveolar type II epithelial cells. In acellular assays, we also assessed particle oxidative potential and the presence of microorganisms. The results showed that volcanic ash and desert dust exhibit intrinsically different particle morphology, surface textures and chemistry, and variable mineralogical content. We found that Gobi Desert dust is more bioreactive than freshly erupted volcanic ash and Arizona test dust, which is possibly linked to the presence of microorganisms (bacteria) and/or nanoscale elongated silicate minerals (potentially clay such as illite or vermiculite) on particle surfaces.
Quasi‐Periodic Emissions in Saturn's Magnetosphere and Their Effects on Electrons
Authors: Teng S. , Wang Dedong , Drozdov Alexander Y. , Shprits Yuri Y. , Wu Zeyin , Hao Y. X. , Yao Z. , Zhang J. 
Published: January 2025

AbstractInvestigations into quasiperiodic (QP) whistler mode emissions within Saturn's magnetosphere have uncovered distinctive characteristics of these emissions, which display a nearly periodic rising tone structure in the wave spectrogram, characterized by modulation periods of several minutes. These QP emissions are predominantly observed at low L‐shells around 5 and near the magnetic equator. Utilizing a quasi‐linear analysis framework, we evaluate the effects of these waves on the dynamics of energetic electrons. Our analysis suggests that these QP emissions can efficiently cause the loss of electrons within the energy range from 10 to 60 keV over a timescale of tens of minutes. By incorporating these findings into Fokker‐Planck simulations, we find minimal acceleration effects. This study is the first to examine QP emissions and their implications for energetic electron dynamics in Saturn's magnetosphere, highlighting their potentially significant contribution to the magnetospheric processes and dynamics.
Systematically developing a registry of splice-site creating variants utilizing massive publicly available transcriptome sequence data
Authors: Iida Naoko , Okada Ai , Kobayashi Yoshihisa , Chiba Kenichi , Yatabe Yasushi , Shiraishi Yuichi 
Published: January 2025

AbstractGenomic variants causing abnormal splicing play important roles in genetic disorders and cancer development. Among them, variants that cause the formation of novel splice-sites (splice-site creating variants, SSCVs) are particularly difficult to identify and often overlooked in genomic studies. Additionally, these SSCVs are frequently considered promising candidates for treatment with splice-switching antisense oligonucleotides (ASOs). To leverage massive transcriptome sequence data such as those available from the Sequence Read Archive, we develop a novel framework to screen for SSCVs solely using transcriptome data. We apply it to 322,072 publicly available transcriptomes and identify 30,130 SSCVs. Among them, 5121 SSCVs affect disease-causing variants. By utilizing this extensive collection of SSCVs, we reveal the characteristics of Alu exonization via SSCVs, especially the hotspots of SSCVs within Alu sequences and their evolutionary relationships. We discover novel gain-of-function SSCVs in the deep intronic region of the NOTCH1 gene and demonstrate that their activation can be suppressed using splice-switching ASOs. Collectively, we provide a systematic approach for automatically acquiring a registry of SSCVs, which facilitates the elucidation of novel biological mechanisms underlying splicing and serves as a valuable resource for drug discovery. The catalogs of SSCVs identified in this study are accessible on the SSCV DB (https://sscvdb.io).