bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mortality of Patients With Candidemia and COVID-19: A Systematic Review With Meta-analysis
Authors: Colaneri Marta , Giusti Emanuele Maria , Genovese Camilla , Galli Lucia , Lombardi Andrea , Gori Andrea 
Published: July 2023

AbstractMortality of candidemia in coronavirus disease 2019 (COVID-19) patients has not been deeply studied despite evidence suggesting an increased occurrence. We performed a systematic review and meta-analysis to summarize the available evidence about these patients’ mortality and length of stay. Data about the in-hospital, all-cause and 30-day mortality, and length of stay were pooled. Subgroup analyses were performed to assess sources of heterogeneity. Twenty-six articles out of the 1915 records retrieved during the search were included in this review. The pooled in-hospital mortality was 62.62% (95% CI, 54.77% to 69.86%), while the mortality in intensive care unit (ICU) was 66.77% (95% CI, 57.70% to 74.75%). The pooled median in-hospital length of stay was 30.41 (95% CI, 12.28 to 48.55) days, while the pooled median length of stay in the ICU was 28.28 (95% CI, 20.84 to 35.73) days. The subgroup analyses did not identify the sources of heterogeneity in any of the analyses. Our results showed high mortality in patients with candidemia and COVID-19, suggesting the need to consider screening measures to prevent this life-threatening condition.
Failure and Success in Agency
Authors: Heering David 
Published: July 2023

Abstract
Agency often consists in performing actions and engaging in activities that are successful. We pour glasses, catch objects, carry things, recite poems, and play instruments. It has therefore seemed tempting in recent philosophical thinking to conceptualise the relationship between our agentive abilities and our successes as follows: (Success) S is exercising their ability to ϕ only if S successfully ϕ-s. This paper argues that (Success) is false based on the observation that agency also often consists in making mistakes. We bungle things. We spill water, we miss objects thrown at us, we drop things, misremember lines, and mess up songs. I argue that these mistakes, doings that fall short of being a φ-ing, can only be understood as subpar exercises of the ability to φ. Since this understanding is incompatible with (Success), the thesis should be given up.
Trajectories of Informal and Formal Social Participation After Retirement
Authors: Lim-Soh Jeremy , Ang Shannon , Malhotra Rahul 
Published: July 2023

Abstract
Literature suggests that on average, social participation declines after retirement. However, there likely remains substantial variability in individual experiences. We rely on seven waves of the Korean Longitudinal Study of Aging to identify contrasting social participation trajectories of individuals 45 years and older after leaving work, and their individual-level correlates. Informal and formal social participation were measured through self-reported frequencies of meeting a friend and attending a group respectively. Group-based trajectory modeling delineated heterogeneous changes over time and multinomial logit regressions estimated individual-level correlates of the trajectories. While a minority of respondents experienced trajectories of decreasing social participation (6%–12%), a majority exhibited stable trajectories (79%–81%), and some even experienced increasing participation (7%–8%). There was also a U-shaped trajectory of decline and recovery in formal social participation (7%). Our findings challenge the belief that disengagement is the norm and illustrate the heterogeneous experiences of social participation after retirement. Returning to work, vs. stopping work for an extended period, was associated with favorable trajectories, pointing to the strong connection between work and social participation, and the potential for interventions that promote bridge employment and lifelong learning. Interestingly, the high stable trajectory of informal participation was associated with certain factors that may be considered vulnerabilities, such as being older, female, single, living in non-metropolitan regions, and retiring from irregular work. This highlights the possibility that despite facing challenges, older adults can aspire towards high social participation.
VThe Early Sixteenth Century
Authors: Smith Edward 
Published: July 2023

Abstract
This chapter has five sections: 1. General: Drama and Prose; 2. General: Verse; 3. More; 4. Skelton; 5. Wyatt
In a sign of the rude health of critical literature on earlier Tudor topics, 2021 featured a broad-spanning range of articles and chapters that focused as much, if not more, on writers and works hitherto accorded little attention as on the canonical figures of the period. A case in point is the fact that more articles on Stephen Hawes saw the light of print (three) than on Henry Howard, Earl of Surrey (none).
Complex regional pain syndrome
Authors: Mills Micayah , Howell Christopher M. 
Published: July 2023

ABSTRACT
Complex regional pain syndrome (CRPS), formerly called reflex sympathetic dystrophy (RSD), is a chronic pain phenomenon associated with an alteration in peripheral and central pain perception in a localized body region. Because of the many risk factors associated with this phenomenon, the true nature of the disease risk and clinical course are a challenge to predict. After the diagnosis is confirmed and treatment is provided promptly, clinicians must consider patient health and function holistically to foster improvement in overall quality of life.
Fluorescence-guided Two-port Robotic Gastrectomy Versus Conventional Laparoscopic Gastrectomy: A Nonrandomized Controlled Trial
Authors: Choi Seohee , Kim Na Young , Kim Youn Nam , Park Sung Hyun , Kim Ki-Yoon , Cho Minah , Kim Yoo Min , Hyung Woo Jin , Kim Hyoung-Il 
Published: July 2023

Objective:
To compare the number of retrieved lymph nodes between conventional laparoscopic gastrectomy (CLG) and robotic gastrectomy integrated with fluorescence guidance and a two-port system (integrated robotic gastrectomy, IRG).

Background:
The benefits of robotic surgery over laparoscopic surgery for gastric cancer have not yet been established. Using built-in features of robotic system, further benefit can be provided to the patients with effective lymphadenectomy and enhanced recovery.

Methods:
A nonrandomized controlled trial was performed by a single surgeon at single-center, tertiary referral hospital between January 2018 and October 2021. Overall, 140 patients scheduled to undergo minimally invasive subtotal gastrectomy for early gastric cancer were enrolled. The primary endpoint was the number of retrieved lymph nodes. Secondary endpoints were complications, hospital stay, pain score, body image, and operative cost.

Results:
This study analyzed 124 patients in the per-protocol group (IRG, 64; CLG, 60). The number of retrieved lymph nodes was higher in the IRG group than those in the CLG group (IRG vs CLG; 42.1 ± 17.9 vs 35.1 ± 14.6, P = 0.019). Moreover, other surgical parameters, such as hospital stay (4.1 ± 1.0 vs 5.2 ± 1.8, P < 0.001) and body image scale (better in 4 of the 10 questions), were significantly better in the IRG than in the CLG.

Conclusions:
Robotic surgical procedures integrated with fluorescence guidance and a reduced-port system yielded more retrieved lymph nodes. In addition, the IRG group showed better perioperative surgical outcomes, particularly regarding the length of hospital stay and postoperative body image.

Trial registration:
NCT03396354
Geriatric Intertrochanteric Fractures: What is the optimal follow-up period?
Authors: Green John , Watson J. Tracy , Philip Shaheen  , Kuldjanov Djoldas 
Published: July 2023

Abstract

Objective:
To evaluate operatively treated intertroch fracture patients in order to determine the optimal follow-up to ensure complete fracture healing and recognize complications.

Design:
This was a retrospective cohort review of patients, presenting with an intertrochanteric hip fracture, treated with a cephallomedullary nail (CMN) or sliding hip screw.(SHS).

Setting:
Patients were treated at an Academic Level 1 trauma center. The trauma database matched with CPT codes 27244 and 27245 to identify patients over the age of 60, treated with CMN or SHS. Inclusion criteria included isolated intertroch fractures (not pathologic), complete radiographic and clinical data, with at least 1 year follow-up. 497 patients were identified. 249 patients met inclusion criteria with 194 patients studied.

Intervention:
All patients underwent operative fixation for their isolated intertroch fractures with either CMN or SHS.

Main Outcome Measurements:
Radiographic parameters included time to union, neck shaft angle, tip apex distance, and femoral neck screw telescoping (shortening)for both CMS and SHS combined. Post-operative complications were recorded.

Results:
Union was achieved at a mean of 64.8+/-30.7 days. Mortality (n=12), infection (n=4), and implant failure (n=5) occurred within three months . Neck shaft angle changed prior to 3 months. Significant neck shortening for both CMN and SHS occurred within 6 weeks. (p=<0.001). Major complications occurred early, within 3 months.

Conclusion:
Radiographic parameters occurred during the first 3 months . Most fractures healed by three months, the remainder by 6 months. Routine follow up for 6 months is more than sufficient for most of these fractures.

Level of evidence:
Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
Surgeon Preference for Prophylactic Contralateral Fixation in Slipped Capital Femoral Epiphysis (SCFE) Patients: A Nationwide POSNA Survey Study
Authors: Donnelly Megan R. , Layne Jonathan E. , Castañeda Pablo G. 
Published: July 2023

Background:
It is estimated that 11% to 60% of unilateral slipped capital femoral epiphysis (SCFE) patients will develop contralateral pathology, usually within 18 months after the first event. Despite this, prophylactic fixation remains controversial, and there is significant variability in surgeon preferences. Thus, this study aimed to determine which factors predict surgeon preferences for prophylactic contralateral pinning in SCFE patients.

Methods:
We designed a survey for pediatric orthopedic surgeons to collect data on (1) surgeon and hospital characteristics, (2) individual preference for contralateral SCFE pinning in three disparate hypothetical scenarios, and (3) personal risk-aversion traits. The questionnaire was distributed across the United States by the POSNA Evidence-Based Orthopaedics Committee. All POSNA members were eligible to respond. We performed analyses to evaluate the role of patient risk factors in hypothetical surgical decision-making and to determine if surgical training, hospital characteristics, and geographic region influenced prophylactic pinning in a surgeon’s real-life practice.

Results:
A total of 126 POSNA members responded to the survey. In the last year, a median of 6.5 SCFE patients was seen per surgeon (1243 patients total). A median of 10% of those patients underwent prophylactic contralateral fixation. In multiple analyses, surgeons were influenced by body mass index, open triradiate cartilage, patient race, various endocrine abnormalities, and specific radiographic measurements when deciding to fix the contralateral side prophylactically. Moreover, in multivariate regression, more years in practice and a hospital size of 500+ beds predicted fewer prophylactic fixation procedures (all P<0.05). Surgeons practicing in the South Atlantic, New England, and Mountain regions of the United States estimated the highest rate of contralateral pinning.

Conclusions:
This study’s findings suggest that multiple factors influence surgeons’ decisions to prophylactically fix the contralateral side in SCFE patients. Surgical training, hospital characteristics, and geographical regions played a role in decision-making.

Level of Evidence:
N/A
The Difference in Tibial Tuberosity to Trochlear Groove Distance Between CT and MRI Arises From the Degree of Knee Flexion During Imaging
Authors: Bae Kunhyung , Aldosari Amaal Mohammed , Kang Michael Seungcheol 
Published: July 2023

Background:
Tibial tuberosity to trochlear groove distance (TT-TG) has been reported to have different values according to imaging modalities, usually higher in computed tomography (CT) than in magnetic resonance imaging (MRI). This difference is thought to be caused by the degree of knee flexion during imaging, but few studies have aimed to elucidate the cause.

Methods:
Five hundred eight patients with knee CT or MRI performed between ages of 6 to 16 years without underlying diseases affecting the musculoskeletal system were included. This study was conducted in 2 statistical ways. (1) Propensity score matching was performed for the imaging modality, and the bony TT-TG was compared between the 2 matched groups. (2) A regression model was fitted with 484 patients with either CT or MRI (a training set), and validation of the fitted model was performed with 24 patients with both CT and MRI simultaneously taken within a week (a test set). The predicted TT-TG values were compared with the measured values.

Results:
(1) Eighty-one patients were successfully matched by propensity score (all the standardized mean differences < 0.1) for each modality. In the matched patients, there was no significant difference in TT-TG according to the imaging modality (11.3 ± 3.7 mm for CT, 10.4 ± 3.8 mm for MRI, P = 0.126). (2) For the model fitting, different linear models were fitted before and after 10 degrees of knee flexion angle because there was a sharp change in TT-TG when the knee flexion angle was <10 degrees. The predicted TT-TG values did not significantly differ from the measured values (10.2 ± 4.3 mm vs. 9.0 ± 5.1 mm, P = 0.124).

Conclusions:
This study is the first to statistically prove that the difference between TT-TG in MRI and CT originates from the different degrees of knee flexion. In addition, although more studies are needed, authors recommend imaging to be performed with the knee flexed at least 10 degrees for more reliable measurements because TT-TG changes sharply if the knee flexion angle is <10 degrees.

Level of Evidence:
III.
Moving from Interest to Engagement—Understanding the Research Capacity Building Needs of Rehabilitation Doctors
Authors: Geraghty Timothy J. , Foster Michele M. , Burridge Letitia H. 
Published: July 2023

Introduction:
Doctors working in rehabilitation settings have specialized clinical skills and experience, but research activity may be constrained by time pressures and inadequate current skills. This means missed opportunities to contribute to the evidence-base for better clinical practice and outcomes for people living with disabling, chronic complex conditions. This research aimed to understand rehabilitation doctors' research needs, experience, and aspirations to enable future training initiatives that are tailored to their practice context.

Methods:
This exploratory sequential mixed-method study comprised a survey followed by focus groups. Rehabilitation doctors from three health services in south-east Queensland, Australia completed an online survey incorporating the Research Spider to explore their research experience, confidence, interest, opportunity, and intent. Focus groups explored the survey results and participants' views regarding strategies to build research capacity.

Results:
The major findings were the gap between high research interest and low experience, confidence and opportunity; and fundamental research skills were identified as priority training topics. These findings support previous research. However, rehabilitation doctors may also have a self-expectation that, as competent clinicians, they should necessarily also be research-competent, and hold misperceptions regarding the shared nature of health services research.

Discussion:
Protected time and funding may enhance engagement with research to generate specialty-relevant evidence for practice. To this end, a research capacity building initiative in the form of a series of self-directed learning packages has been developed and implemented. A tailored workshop to strengthen rehabilitation doctors' research skills and engagement has also been developed for implementation.
Is Education Enough to Change the Practice of Monitoring of Blood Pressure in Outpatient Clinics? Case Report
Authors: Smith Leslie M. , Muralidharan Sindhuja , Stanek Diana , Yorke Amy M. 
Published: July 2023

Purpose:
Hypertension (HTN) is a prevalent and preventable risk factor for several medical conditions that can lead to death. The purpose of this study was to investigate the frequency of physical and occupational therapists taking blood pressure (BP) in outpatient clinics before and after education focused on the clinical importance of monitoring BP.

Methods:
This pre/posttest model consists of 2 phases. In phase 1, physical and occupational therapists were surveyed regarding attitudes, behaviors, and barriers toward monitoring BP; and electronic medical records (EMR) were audited to determine frequency of BP documentation. For phase 2, educational webinars were developed highlighting the importance of BP monitoring and followed by another EMR audit.

Results:
Nine clinicians participated in our survey. Survey results indicated that one-third agreed that BP should be monitored during evaluations, but 100% responded that they rarely take BP. An audit of 488 EMR charts pre-education showed there was no BP documented. Three months after education, another 237 EMR charts were audited, with a 12.7% improvement in the frequency of BP documented. A chi-square analysis showed that this improvement was statistically significant (P < .001).

Conclusions:
Therapists did not monitor and document BP. After the webinar series, there was a significant increase, however still below recommendations for monitoring BP.
Local Regrowth and the Risk of Distant Metastases Among Patients Undergoing Watch-and-Wait for Rectal Cancer: What Is the Best Control Group? Muticenter Retrospective Study
Authors: São Julião Guilherme Pagin , Fernández Laura M. , Vailati Bruna Borba , Habr-Gama Angelita , Azevedo José , Santiago Inês , Parés Oriol , Parvaiz Amjad , Vendrely Véronique , Rullier Anne , Rullier Eric , Denost Quentin , Perez Rodrigo Oliva 
Published: July 2023

BACKGROUND:
A proportion of patients that achieve a clinical complete response may develop local regrowth. While salvage appears to provide appropriate local control, the risk of distant metastases is less known.

OBJECTIVE:
Compare the risk of distant metastases between patients that achieve a complete clinical response (watch-and-wait strategy) and subsequent local regrowth to patients managed by surgery after chemoradiation.

DESIGN:
Retrospective multicenter cohort study.

SETTINGS:
This study used data of patients from 3 institutions that were treated between 1993 and 2019.

PATIENTS:
Patients with initial clinical complete response (after neoadjuvant therapy) followed by local regrowth and patients with near-complete pathological response (≤10%) after straightforward surgery after chemoradiation.

MAIN OUTCOME MEASURES:
Univariate/multivariate analysis was performed to identify risk factors for distant metastases. Kaplan-Meier curves were created (log-rank test) to compare survival outcomes. Analysis were performed using time-zero as last day of radiation therapy (1) or as date of salvage resection (2) in the local regrowth group.

RESULTS:
Twenty-one of 79 patients with local regrowth developed distant metastases while only 10 out of 74 after straightforward surgery (p = 0.04). Local regrowth and final pathology (ypT3-4) were the only independent risk factors associated with distant metastases. When using date of salvage resection as time-zero, distant-metastases-free survival rates was significantly inferior for patients with local regrowth (70 vs. 86%; p = 0.01).

LIMITATIONS:
Small number of patients, many neoadjuvant therapies, selection bias.

CONCLUSIONS:
Patients undergoing watch-and-wait who develop local regrowth are at higher risk for development of distant metastases compared to patients with near-complete pathological response managed by surgery upfront after chemoradiation.
A Descriptive Analysis of Access to Assistive Technology in Children With Acquired Brain Injury: The Right to Assistive Devices
Authors: Fins Joseph J. , Knitter Julie , Mukherjee Debjani , Conti Karen , Donleavy-Hiller Barbara , Gerber Linda M. , Hersh Jennifer E. , Kotorac-Erlbaum Rita , Milch Barbara , Klein Scott M. 
Published: July 2023

Objective:
Pediatric clinicians caring for children with acquired brain injury have noted that many individuals requiring assistive technology (AT) go unserved or face delays until devices are obtained, with potential adverse implications for recovery and development. In this article we map the pathways by which AT is prescribed and assess delays and barriers to access.

Methods:
We conducted a retrospective chart review of patients with moderate to severe brain injury admitted to Blythedale Children's Hospital over a 2-year period using a database drawn from the medical record.

Results:
We identified 72 children diagnosed with brain injury requiring at least 1 device. Devices were used to improve mobility and positioning, self-care, safety, and communication, and enable access to other technologies and foster social integration. We found that 55% of devices were delivered, with most deliveries to home or the hospital's outpatient department for fitting, training, and instruction. Time to delivery ranged from 12 to 250 days with an average of 69.4 days. Twenty percent of nondeliveries were attributable to change in medical status, transfer to a skilled nursing facility, or continued inpatient status, while 31% were canceled by the family. Other nondeliveries were attributed to insurance coverage. We also found that the medical record is not designed for the longitudinal tracking of devices, indicating the need for a prospective process to document the AT trajectory.

Conclusion:
Instead of tolerating delays and denials, there should be a normative expectation that children have a right to medically necessary devices, consistent with disability law. This analysis was undertaken as a step toward formulating a prospective means of tracking AT recommendations, approvals, denials, and/or deliveries. Our findings should be understood as a promissory note toward structural reforms that are reflective of society's responsibility to better meet the needs of vulnerable children and their families.
Impact of Interprofessional Communication on Safety in the Neonatal Intensive Care Unit
Authors: Thomas Tyler S. , Chance Kasey , Spurlock Amy 
Published: July 2023

Background:
In light of the complex advances in neonatal intensive care units (NICU), it is essential that healthcare providers (HCPs) are equipped with the appropriate skills to effectively communicate between disciplines to provide safe, quality care. However, many HCPs acknowledge that they are not confident in their ability to communicate effectively with peers.

Purpose and Design:
This study aimed to identify perceived barriers and facilitators of communication among HCPs in a NICU setting. This study took place in a 60-bed NICU that utilized multiple disciplines of HCPs. Using a qualitative, cross-sectional design, 2 surveys were administered, namely, a demographic survey with open-ended questions and the Safety Attitudes Questionnaire (SAQ).

Results:
Findings indicated inverse relationships in age/experience and perceptions of management. Total SAQ scores ranged from 45 to 77 (N = 28, M = 62.47, SD = 9.40). The SAQ highlight that total scores above 75 correspond with positive perceptions of safety in the NICU.

Conclusion:
The statistical evidence derived from this study contributes to the evaluation of HCP-perceived communication barriers and facilitators. The identification of perceived barriers and facilitators of communication in an ICU setting may serve as a distinct, evidence-based foundation to develop interventions that emphasize the value of communication.