bluuebunny/crossref_metadata_2025_split huggingface dataset:
Control of stochastic and inverse stochastic resonances in a liquid-crystal electroconvection system using amplitude and phase noises
Authors: Huh Jong-Hoon , Shiomi Masato , Miyagawa Naoto 
Published: June 2023

Abstract
Stochastic and inverse stochastic resonances are counterintuitive phenomena, in which noise plays a pivotal role in the dynamics of various biological and engineering systems. Even though these resonances have been identified in various systems, a transition between them has never been observed before. The present study demonstrates the presence of both resonances in a liquid crystal electroconvection system using combined amplitude and phase noises, which correspond to colored noises with appropriate cutoff frequencies (i.e., finite correlation times). We established the emergence of both resonances and their transition through systematic control of the electroconvection threshold voltage using these two noise sources. Our numerical simulations were experimentally confirmed and revealed how the output performance of the system could be controlled by combining the intensity and cutoff frequency of the two noises. Furthermore, we suggested the crucial contribution of a usually overlooked additional phase noise to the advancements in various noise-related fields.
Date Fruits
Authors: Chamon Afrose , Parash Md. Abrar Hasin , Fahad Jannatul Islam , Hassan S.M. Nazmul , Ahmed Santo Kabir , Mushrat Maesha , Islam Nafisha , Hasan Taukir , Atiya Zarin , Mondol Md. Nadiruzzaman 
Published: June 2023

Abstract

Background
Heavy metals are drawing much attention and excess accumulation of heavy metals in frequently consumed food (e.g., vegetables, fruits) is a serious threat to human health as well as contamination of the food chain. The concentration of heavy metals in Ajwa dates collected from three markets in Dhaka, Bangladesh and from Madinah was analyzed. Average daily intake (ADI), hazard quotient (HQ), and hazard index (HI) were also estimated to assess the health risks posed by the intake of heavy metals from the consumption of studied dates.
Results
The presence and degree of contamination was assessed for chromium (Cr), cadmium (Cd), lead (Pb), nickel (Ni), copper (Cu), zinc (Zn), iron (Fe), and manganese (Mn). Concentrations of Cd and Ni exceeded the maximum permissible limit (MPL) in some date fruit samples. ADI was found to be lower than the maximum permitted tolerable daily intake in all samples. Hazard indices of samples collected from new market and Badamtali exceeded unit value, due to higher human activity and higher vehicular traffic, signifying potential health hazard from the dietary intake of the studied date fruits. Results of this study, reveals that most of studied heavy metals are within safe limit with respect to maximum allowable levels (MAL) in some date samples and were safe for consumption.
Conclusions
Higher concentrations of Cd and Ni were found in some samples. Hence, the consumption of dates with higher metal concentration has higher potential health risks. This study suggests that regular monitoring of heavy metals in date fruits is essential to prevent health risks associated with consuming heavy metal contaminated fruits.
Role of the revised Baux score in predicting mortality among burn patients in an African low income country; a multicenter prospective cohort
Authors: Baraka Samuel Mandro , Kiswezi Ahmed , Olasinde Anthony Ayotunde , Edyedu Isaac , Molen Selamo Fabrice , Muhumuza Joshua , Zawadi Gift Vulwaghe , Okedi Francis Xaviour 
Published: June 2023

Abstract
Introduction
Burn injury is a major cause of mortality. Majority of the burns occur in low and middle income countries like Uganda. Uganda has limited burn centres and medical resources making a predictor of mortality necessary in allocation of the limited resources. Though the revised Baux (r-Baux) score has been validated and used in many high income countries, no study has assessed the role of r-Baux score in an African low income country; the reason this study was done.
Methods
This was a prospective multicentre cohort that enrolled 101 burns patients with moderate and severe burns admitted in 3 tertiary hospitals in western Uganda. Follow up was done until discharge, documenting mortality. A receiver operator characteristic curve was used to determine the role of r-Baux score in predicting mortality.
Results
This study included 101 patients, with a mean age of 21.3 (SD = 16.8) years. The majority of the participants were male (69.3%). The area under the curved for r-Baux score at predicting mortality was 0.943 (p < 0.001). The most appropriate cut off was determined to be 74.5. At this cut off, r-Baux score predicted mortality with a sensitivity of 100% and specificity of 83.5%. For every one unit increase in r-Baux score, the odds of mortality increased by 1.1 times (p = 0.001) while controlling for severity.
Conclusion
The r-Baux score was found to be excellent at predicting mortality among burn patients in Uganda and therefore should be done for all patients at admission, in order to predict mortality and do proper planning.
Key Sets Analysis of Compiler Vector Options for H.264 Video Compression Algorithms Implemented on the MIPS SIMD Architecture
Authors: Bogaevskiy Danil , Ezhov Sergey , Fedoseev Petr , Butusov Denis , Elkamchouchi Dalia H. , Alqahtani Malak S , Abbas Mohamed , Soufiene Ben Othman , Kaplun Dmitrii 
Published: June 2023

Abstract
The paper offers metrics to evaluate the image processing performance and video processing programs implemented on the MIPS SIMD Architecture (MSA). These metrics were also used to analyze and present key sets for the GCC compiler. As a result of the analysis, which was performed earlier, numerical representations of each parameter of four algorithms (CABAC, CAVLC, FDCT-IDCT, and Motion Estimation), used in the H.264 video compression standard, were calculated, and 5952 key sets were obtained, respectively. The weight coefficients were determined for each of the key parameters according to the Saati hierarchy analysis methodology. After that, using weight functions, 372 recommended sets of keys were determined, the target functions of which are maximal for each of the 4 algorithms considered.
Ketogenic diet regulates cardiac remodeling and calcium homeostasis in diabetic cardiomyopathy
Authors: Lee Ting-I , Trang Nguyen Ngoc , Lee Ting-Wei , Higa Satoshi , Kao Yu-Hsun , Chen Yao-Chang , Chen Yi-Jen 
Published: June 2023

Abstract
Background
Ketogenic diet (KD) might alleviate patients with diabetic cardiomyopathy. However, the underlying mechanism remains unclear. Myocardial function and arrhythmogenesis depend on the homeostasis of calcium (Ca2+). We investigated the effects of KD on Ca2+ homeostasis and electrophysiology in diabetic cardiomyopathy.
Methods
Male Wistar rats were created to have diabetes mellitus (DM) by applying streptozotocin (65 mg/kg intraperitoneally), and they were treated for 6 weeks with a normal diet (ND) or KD. Our electrophysiological and Western blot analyses assessed myocardial Ca2+ homeostasis in ventricular preparations in vivo.
Results
Unlike those on KD, DM rats treated with ND exhibited a prolonged QTc interval and action potential duration. Compared to control and DM rats on KD, DM rats treated with ND also showed lower intracellular Ca2+ transients, sarcoplasmic reticular Ca2+ content, sodium (Na+)-Ca2+exchanger currents (reverse mode), L-type Ca2+ contents, sarcoplasmic reticulum ATPase contents, Cav1.2 contents, phosphorylated phospholamban/phospholamban ratios, and phosphorylated ryanodine receptor 2 (RyR2) at serine 2808/RyR2 ratios but higher Ca2+/calmodulin-dependent protein kinase II (CaMKII-δ) levels. Moreover, DM rats treated with ND demonstrated a higher frequency and incidence of Ca2+ leak, mitochondrial and cytosolic reactive oxygen species, Na+/hydrogen-exchanger currents, and late Na+ currents than control and DM rats on KD.
Conclusion
KD treatment may attenuate the effects of DM-dysregulated Na+ and Ca2+ homeostasis, contributing to its cardioprotection in DM.
Fusion of myofibre branches is a physiological feature of healthy human skeletal muscle regeneration
Authors: Højfeldt Grith , Sorenson Trent , Gonzales Alana , Kjaer Michael , Andersen Jesper L. , Mackey Abigail 
Published: June 2023

Abstract
Background: The occurrence of hyperplasia, through myofibre splitting, remains a widely debated phenomenon. Structural alterations and fibre typing of skeletal muscle fibres, as seen during regeneration and in certain muscle diseases, can be challenging to interpret. Neuromuscular electrical stimulation can induce myofibre necrosis followed by changes in spatial and temporal cellular processes. 30 days following electrical stimulation, remnants of regeneration can be seen in the myofibre and its basement membrane as the presence of small myofibres and encroachment of sarcolemma and basement membrane (suggestive of myofibre branching/splitting). The purpose of this study was to investigate myofibre branching and fibre type in a systematic manner in human skeletal muscle undergoing adult regenerative myogenesis.
Methods: Electrical stimulation was used to induce myofibre necrosis to the vastus lateralis muscle of one leg in 5 young healthy males. Muscle tissue samples were collected from the stimulated leg 30 days later, and from the control leg for comparison. Biopsies were sectioned and stained for dystrophin and laminin to label the sarcolemma and basement membrane, respectively as well as ATPase, and antibodies against type I and II myosin, and embryonic and neonatal myosin. Myofibre branches were followed through 22 serial sections (264mm). Single fibres and tissue blocks were examined by confocal and electron microscopy, respectively.
Results: Regular branching of small myofibre segments was observed (median length 144mm), most of which were observed to fuse further along the parent fibre. Central nuclei were frequently observed at the point of branching/fusion. The branch commonly presented with a more immature profile (nestin+, neonatal myosin+, disorganised myofilaments) than the parent myofibre, together suggesting fusion of the branch, rather than splitting. Of the 210 regenerating muscle fibres evaluated, 99.5% were type II fibres, indicating preferential damage to type II fibres with our protocol. Furthermore, these fibres demonstrated 7 different stages of “fibre type” profiles.
Conclusions: By studying the regenerating tissue 30 days later with a range of microscopy techniques, we find that so-called myofibre branching or splitting is more likely to be fusion of myotubes and is therefore explained by incomplete regeneration after a necrosis-inducing event.
Impact Calculation Of The Players Using The Cricket Commentary Corpus
Authors: GOEL AMAN , Singh Piyush Pratap 
Published: June 2023

Abstract
This research paper focuses on the use of natural language processing techniques for extracting insights from cricket commentary. This study proposes a framework that considers the commentary text, evaluates each player's performance, and gives value-based scores to define their impacts. This research relies on sentiment analysis, topic modeling, and NER to analyze a large corpus of cricket commentary data and develop a model for calculating the impacts of the players. The findings of this study will be of great interest to sports analysts, coaches, players, and fans of the game. The literature review of this paper covers the existing works on textual analysis and analysis using commentary corpora. This study has the potential to revolutionize player performance evaluation in cricket by identifying "hidden gems" that may have been overlooked based on conventional statistics alone.
MiR-302a reprogrammed fibroblast-derived induced anti-aging neural stem cells improve cognition and prolong lifespan in Alzheimer's disease model
Authors: Li Yuanyuan , Sun Jing , Zheng Yuanyuan , Xu Tingting , Zhang Yanan , Wang Yuesi 
Published: June 2023

Abstract
Background: Neural stem cells (NSC) are essential for maintaining tissue homeostasis and promoting longevity in living organisms. As a promising approach to treating neurodegenerative diseases, NSC transplantation has been hampered by crucial issues such as cellular senescence, immune rejection, and low cell viability.
Methods: MiR-302a was used to reprogram human and mouse fibroblast cells into induced neural stem cells (iNSCs). In vitro, differentiation experiments were performed to demonstrate that iNSCs have the ability to differentiate into neurons, astrocytes, and oligodendrocytes. INSCs were transplanted into nude mice to evaluate cell survival, differentiation, and tumor formation in vivo. Multi-electrode arrays were used to determine that the differentiated neurons from iNSCs have mature electrophysiological functions. INSCs were treated with oxidative damage to test their antioxidant and anti-aging abilities. The supernatant of iNSCs was used to treat aged cells to determine their antioxidant and anti-aging effects. INSCs were transplanted into SAMP8 rapid aging Alzheimer's disease (AD) mouse model for behavioral tests to evaluate the improvement and therapeutic effects of iNSCs treatment on cognitive function and memory. Tests were also performed to assess lifespan extension, improved glycemic control, promoted motor ability recovery, improved reproductive ability, and improved hearing.
Results: We report that a single miR-302 factor alone can effectively reprogram human and mouse fibroblasts directly into iNSCs within 2-3 days, confirmed by cell phenotype, molecular characterization, and functional analysis. The anti-aging factors Nrf2, Sirt6, and Foxo3 are highly expressed in induced neural stem cells reprogrammed by miR-302a (miR-302a-hiNSCs). Compared to other iNSCs, miR-302a-hiNSCs showed delayed aging and increased resilience to oxidative stress. MiR-302a-hiNSCs were implanted into SAMP8 mice to improve cognition, extend longevity by 40.625%, increase fatigue resistance, and enhance blood sugar control, hair regrowth, and reproduction.
Conclusion: Our study highlights the potential of iNSCs generated based on miR-302a as a promising therapeutic approach for treating various age-related diseases and conditions. We found the iNSCs treatment to improve lifespan, cognitive abilities in late-stage AD, fatigue resistance, hair regeneration, blood glucose, and fat metabolism, renal function, reproductive function, and hearing loss.
The nonlinear optical properties of self-assembled InAs/GaAs quantum dot under effect of temperature and hydrostatic pressure
Authors: Jaouane M. , El-Bakkari K. , Al E. B. , Sali A. , Ungan F. 
Published: June 2023

Abstract

In this study, we have scrutinized the influences of the temperature \(\left(T\right)\) and hydrostatic pressure \(\left(P\right)\) on the nonlinear and linear optical properties of a core/shell quantum dot (QD) system with Screened Modified Kratzer potential (SMKP). To realize this goal, we have examined the energy levels and their associated wave functions using the diagonalization method within the effective mass approximation. Analytical terms for absorption coefficients (ACs) and relative refractive index changes (RRICs) are exploited by means of the density matrix approach. The numerical outcomes are offered for typical InAs/GaAs core/shell QD system. The dependency of SMKP, dipole transition matrix element and electron energies of the ground (\(1s\)) and first excited state (\(1p\)) on the \(P\) and \(T\) that are varied over a range. Obtained numerical calculation results revealed that the \(P\) and \(T\) impacts the magnitude and position of the resonant peaks that characterize the ACs and RRICs.
Combining C-reactive protein, procalcitonin, and serum albumin to predict long-term mortality in patients with infective endocarditis
Authors: Karaca Banu , Esin Fatma , Tiryaki Muhammet Mücahit , Kiris Tuncay 
Published: June 2023

Abstract
Aims
To determine the predictive value of C-reactive protein plus albumin plus procalcitonin (PCT) for long-term mortality in patients with infective endocarditis (IE).
Methods
The current study included 261 IE patients between February 2008 and 31 December 2021. CRP, PCT, and albumin levels were measured within 24 hours of admission. A CRP plus PCT plus albumin points (2–6) was assigned based on the CRP, PCT, and albumin concentrations. The outcome was defined as an all-cause mortality rate at long-term follow-up. The patients were divided into two groups; survivors (n = 112), and non-survivors (n = 149).
Results
The patients in the non-survivors group had higher PCT [5.4 (0.7–19.9) vs 1.1 (0.2–9.1), p = 0.020], and CRP [131 (73.5–187) vs 84.5 (45-138.5), p = 0.010] compared with the patients in the survivors’ group. However, the albumin level was lower in the non-survivors (3.1 ± 0.6 vs 3.5 ± 0.6, p = 0.015). In the multivariate analysis, CRP plus PCT plus albumin points (the patients’ risk groups) was an independent predictor of long-term mortality in IE patients ( each p < 0.05).
Management of adhesive small bowel obstruction: The results of a large prospective trial
Authors: Maienza Elisa , GodirisPetit Gaelle , Noullet Séverine , Menegaux Fabrice , Chereau Nathalie 
Published: June 2023

Abstract
Background: Postoperative adhesive small bowel obstruction (SBO) is a frequent cause of hospital admission in a surgical department. Emergency surgery is needed in a majority of patients with bowel ischemia or peritonitis; most adhesive SBO can be managed nonoperatively. Many studies have investigated benefits of using oral water-soluble contrast to manage adhesive SBO. Treatment recommendations are still controversial. Methods: We conducted an observational prospective monocentric study to test our protocol of management of SBO using Gastrografin®, enrolling 661 patients from January 2008 and December 2021. An emergency surgery was performed in patients with abdominal tenderness, peritonitis, hemodynamic instability, major acute abdominal pain despite gastric decompression, or CT-scan findings of small bowel ischemia. Nonoperative management was proposed to patients who did not need emergency surgery. A gastric decompression with a nasogastric tube was immediately performed in the emergency room for four hours, then the nasogastric tube was clamped and 100 ml of nondiluted oral Gastrografin® was administered. The nasogastric tube remained clamped for eight hours and an abdominal plain radiograph was taken after that period. Emergency surgery was then performed in patients who had persistent abdominal pain, onset of abdominal tenderness or vomiting during the clamping test, or if the abdominal plain radiograph did not show contrast product in the colon or the rectum. In other cases, the nasogastric tube was removed and a progressive refeeding was introduced, starting with liquid diet. Results: 78% of patients with SBO were managed nonoperatively, including 183 (36%) who finally required surgery. Delayed surgery showed a complete small bowel obstruction in all patients who failed the conservative treatment, and a small bowel resection was necessary in 19 patients (10%): among them only 5 had intestinal ischemia. Conclusions: Our protocol is safe and it is a valuable strategy in order to accelerate the decisional making process for management of adhesive SBO, with a percentage of risk of late small bowel resection for ischemia esteemed at 0,1%.
Relative Equilibria and Periodic Orbits in a Binary Asteroid Model
Authors: Bakker Lennard F , Freeman Nicholas J 
Published: June 2023

Abstract
We present a planar four-body model, called the Binary Asteroid Problem, for the motion of two asteroids (having small but positive masses) moving under the gravitational attraction of each other, and under the gravitational attraction of two primaries (with masses much larger than the two asteroids) moving in uniform circular motion about their center of mass. We show the Binary Asteroid Model has (at least) 6 relative equilibria and (at least) 10 one-parameter families of periodic orbits, two of which are of Hill-type. The existence of six relative equilibria and 8 one-parameter families of periodic orbits is obtained by a reduction of the Binary Asteroid Problem in which the primaries have equal mass, the asteroids have equal mass, and the positions of the asteroids are symmetric with respect to the origin. The remaining two one-parameter families of periodic orbits, which are of comet-type, are obtained directly in the Binary Asteroid Problem.
MSC Classification: Primary 70F15 Secondary 37C27
Understanding the pathogenesis of engineered-stone associated accelerated silicosis: the effect of particle chemistry on the lung cell response
Authors: Ramkissoon Chandnee , Song Yong , Yen Seiha , Southam Katherine , Page Simone , Pisaniello Dino , Gaskin Sharyn , Zosky Graeme 
Published: June 2023

Abstract
Background: Accelerated silicosis amongst engineered stone fabricators has been reported in several countries. Up to now, poorly controlled respirable crystalline silica exposure has been considered to be the critical risk factor, however, the potential contribution of other chemical components of engineered stone is poorly understood. We investigated the link between the physico-chemical characteristics of engineered stone and lung cell responses.
Methods: Respirable dust from 50 resin-based engineered stone samples, 3 natural stones and 2 other non-resin-based materials was captured and analysed for crystalline components, elements, resin content, particle size, morphology and zeta potential. Human alveolar epithelial cells and macrophages were challenged in vitro with dust particles and assessed for cytotoxicity and inflammation. Principal component analysis and stepwise linear regression were used to explore the relationship between engineered stone components and the cellular response.
Results: Approximately 90% of the particles had aerodynamic diameters < 600 nm. Ultrafine particles were noted for the two low silica products. Crystalline silica was the main component with metal elements such as Ti, Cu, Co and Fe also present. In epithelial cells, there were marginally significant differences in cytotoxicity (p = 0.061) and IL-6 (p = 0.084) between dust samples. However, IL-8 levels were clearly variable (p < 0.05) while, in macrophages, there was considerable variability in the levels of TNF-α (p < 0.05) and IL-8 (p < 0.05) produced. For the engineered stone samples, quartz explained 11% of the variance (p = 0.019) in macrophage inflammation while Co and Al accounted for 32% of the variance (p < 0.001) in macrophage cytotoxicity. None of the measured characteristics were linked to epithelial cell response and two of the non-engineered stone products induced considerable macrophage inflammation despite their low silica content.
Conclusions: The findings suggest that crystalline silica partially explains the macrophage inflammatory response while aluminium and cobalt contribute to macrophage toxicity. However, a lack of association between the particle characteristics and the epithelial cell response, and the high inflammation induce by some of the other non-engineered stone products, highlights the caution required as new low-silica products enter the market in an effort to reduce disease risk.