bluuebunny/crossref_metadata_2025_split huggingface dataset:
Polymerizable Solvent‐free Organic Liquids: A New Approach for Large Area Flexible and Foldable Luminescent Films
Authors: Wakchaure Vivek Chandrakant , Veer Sairam Dnyaneshwar , Nidhankar Aakash D. , Kumar Viksit , Narayanan Aswini , Babu Sukumaran Santhosh 
Published: June 2023

AbstractThe high demand for light‐emitting and display devices made luminescent organic materials as attractive candidates. Solvent‐free organic liquids are one of the promising emitters among them due to the salient features. However, the inherent limitations of forming sticky and noncurable surfaces must be addressed to become an alternate emitter for large‐area device applications. Herein, we functionalized solvent‐free organic liquids having monomeric emission in bulk with polymerizable groups to improve the processability. The polymerizable group on carbazole, naphthalene monoimide, and diketopyrrolopyrrole‐based solvent‐free liquid emitters enabled on‐surface polymerization. These emitters alone and in combinations can be directly coated on a glass substrate without the help of solvents. Subsequent photo or thermal polymerization leads to stable, non‐sticky, flexible, foldable, and free‐standing large‐area films with reasonably high quantum yield. Our demonstration of the tunable and white light‐emitting films using polymerizable solvent‐free liquids might be a potential candidate in flexible/foldable/stretchable electronics. The new concept of polymerizable liquid can be extended to other functional features suitable for futuristic applications.
Comparative analysis in the performances of four in‐ground lagoon anaerobic digesters treating palm oil mill effluent (POME)
Authors: Mohd Yusof Mohd Amran Bin , Chan Yi Jing , Chong Chien Hwa 
Published: June 2023

AbstractWhile palm oil mill effluent (POME) from different sources will have varying characteristics due to the different process flows in mills, efficient monitoring and performance evaluation of anaerobic digesters in POME treatment are crucial to ensure stable biogas production with minimal operational problems. Therefore, this study aims to evaluate and compare the performances of in‐ground lagoon anaerobic digesters under mesophilic conditions in four different biogas plants (BGPs A, B, C and D) located in Malaysia with respect to total chemical oxygen demand (COD) removal and total biogas produced. Results show that all BGPs are still functioning well with satisfactory methane yields (.135–.364 Nm3CH4/kgCOD removed) and COD removal efficiencies (67%–85%). ANOVA analysis shows that organic loading rate (OLR), temperature (T) and recirculation ratio (RR) have significant effects on the COD removal and biogas production of all four plants. BGP B has the highest amount of biogas produced (4.12 × 105 Nm3/month) and COD removal rate amongst other BGPs due to its most stable and lowest T (<40°C), high RR, and consistent and high COD load. Conversely, BGP D has the lowest COD removal and biogas production, which are mainly contributed by a high COD inlet (92 000 mg/L) and a high T in the anaerobic digester (48.7°C). Despite having a similar design of an anaerobic digester, this comparative study reveals that different BGPs will have different optimum operating conditions and limitations, depending not only on the operating conditions of the BGP (OLR, T and RR) but also on the raw POME quality stemming from the palm oil milling process. A future study would be focused on the optimisation of four BGPs for maximum biogas removal.
A key role of a bio‐based charring‐coupling agent in flame retardant and anti‐dripping performance of polyamide 6/aluminum diethylphosphinate
Authors: Zhang Wei , Li Hui , Cao Weihong , Guo Zhenghong , Fang Zhengping , Li Juan , Chen Peng 
Published: June 2023

AbstractIn this work, an organophosphorus flame retardant (BHD) was synthesized using 4‐formylphenylboronic acid and 1,6‐hexanediamine; a charring‐coupling agent containing epoxy (DE) was synthesized using daidzein and epichlorohydrin. The BHD and DE were reacted and coated on the surface of aluminum diethylphosphinate (ADP) and the product is identified as BD‐ADP. PA6 with 12 wt% BD‐ADP achieves a UL‐94 V‐0 rating and a limiting oxygen index (LOI) value of 30.0 vol%. Substitute 1.0 wt% DE for BD‐ADP, PA6‐1.0E not only achieves a UL‐94 V‐0 rating, but also goes out before dripping. The time to ignition of PA6‐1.0E is 19 s longer than that of PA6. The flame‐retardant mode is the combination of the gas‐phase effect of ADP and the condensed‐phase effect of DE. In addition, the tensile strength and impact strength of PA6‐1.0E are 103.9 MPa and 6.6 kJ/m2which are 35.6% and 43.5% more than that of PA6‐12A. Both BD coating and DE contribute to a strong interfacial adhesion between ADP and PA6 which improves the mechanical properties. The DE plays a key role in the flame retardancy and mechanical properties of PA6 blends.
Diagonallagenholz (DLH) – Ressourceneffizienz durch diagonale Orientierung einzelner Lagen: Bestimmung der Steifigkeitsparameter und Verformungsanalysen
Authors: Arnold Matthias , Maderebner Roland , Dietsch Philipp , Winter Stefan 
Published: June 2023

AbstractDieser Aufsatz befasst sich mit der Entwicklung von diagonal verklebtem Brettsperrholz (Diagonallagenholz – DLH), einem Laminat aus Massivholzlamellen, welche zur Anpassung der Steifigkeitseigenschaften in einem bestimmten Winkel zueinander angeordnet werden. DLH stellt somit eine anwendungsoptimierte Weiterentwicklung von Brettsperrholz (BSP) dar und erreicht bei gleichem Materialeinsatz verbesserte mechanische Eigenschaften. Der Beitrag beschäftigt sich mit der analytischen Herleitung der Steifigkeitsmatrix, der experimentellen Charakterisierung und numerischen Verformungsanalysen. Die Untersuchungen wurden mit spezifischen DLH‐Serien durchgeführt, welche durch die Ausrichtung von Lagen unter Winkeln von ±45° bzw. ±30° (±60°) gekennzeichnet sind. Die Ergebnisse zeigen, dass die Torsionssteifigkeit im Vergleich zu BSP deutlich erhöht ist. Diese Eigenschaft ist vielversprechend für die Anwendung von DLH in Platten unter zweiachsiger Biegebeanspruchung, wie z. B. punktgestützten Flachdecken. Hierbei verspricht die diagonale Ausrichtung einzelner Lagen zudem Homogenisierungseffekte bei der Verteilung von Biege‐ und Schubspannungen. Gleichzeitig führt die diagonale Orientierung einzelner Lagen zu einer Erhöhung der Scheibenschubsteifigkeit, welche hinsichtlich aussteifender Wand‐ und Deckenelemente von großem Interesse ist. Die Forschung an DLH hebt die Relevanz und Eignung diagonal ausgerichteter Lagen in Massivholzelementen für einen effizienteren und damit nachhaltigen Umgang mit der Ressource Holz hervor.
High‐moisture pelleting of corn stover using pilot‐ and commercial‐scale systems: Impact of moisture content, L/D ratio and hammer mill screen size on pellet quality and energy consumption
Authors: Tumuluru Jaya Shankar 
Published: June 2023

AbstractHigh‐moisture pelleting of corn stover was tested in pilot‐ and commercial‐scale systems. For the pilot‐scale study, a 6.35 mm screen size hammer mill ground corn stover was reconditioned to moisture between 14 and 29.6% (w.b.), and 5, 7 and 9 L/D ratio pellet die were used. At 29% corn stover moisture content and L/D ratios of 5 and 9, the bulk density and durability of the pellets were ≤450 kg/m3 and <90% and >540 kg/m3 and >90%, respectively. Increasing the feedstock moisture and L/D ratio increased the pelleting energy. Increasing the hammer mill screen size to 11.11 mm reduced the bulk density but not the durability. The response surface models adequately described the pelleting process (R2 ≥ 0.88), and analysis of variance showed a strong interaction between the process variables and pellet properties. Commercial‐scale testing of high‐moisture pelleting using 6.35 mm ground corn stover bales in the moisture range 24–26% (w.b.) produced pellets with a density of >675 kg/m3 and durability of >98%, whereas increasing the hammer mill screen size to 11.11 mm reduced the bulk density by about 100 kg/m3 but not the durability. The energy consumption of the commercial‐scale unit operations for the high‐moisture pelleting process was in the range 98–124 kW h/ton, which is 64–72% less energy than conventional pelleting that requires energy about 350 kW h/ton for biomass drying from 30% (w.b.) to 10% (w.b.) moisture content before pelleting. Pellets produced using high‐moisture pelleting met International Organization for Standardization and Pellets Fuel Institute international standards. Published 2023. This article is a U.S. Government work and is in the public domain in the USA.
Eating disorder symptoms and control‐seeking behavior
Authors: Slanina‐Davies Ashley , Robinson Oliver J. , Pike Alexandra C. 
Published: June 2023

AbstractObjectiveEating disorders (EDs) are a heterogenous group of disorders characterized by disturbed eating patterns. Links have been made between ED symptoms and control‐seeking behaviors, which may cause relief from distress. However, whether direct behavioral measures of control‐seeking behavior correlate with ED symptoms has not been directly tested. Additionally, existing paradigms may conflate control‐seeking behavior with uncertainty‐reducing behavior.MethodA general population sample of 183 participants completed part in an online behavioral task, in which participants rolled a die in order to obtain/avoid a set of numbers. Prior to each roll, participants could choose to change arbitrary features of the task (such as the color of their die) or view additional information (such as the current trial number). Selecting these Control Options could cost participants points or not (Cost/No‐Cost conditions). Each participant completed all four conditions, each with 15 trials, followed by a series of questionnaires, including the Eating Attitudes Test‐26 (EAT‐26), the Intolerance of Uncertainty Scale, and the Obsessive–Compulsive Inventory—Revised (OCI‐R).ResultsA Spearman's rank test indicated no significant correlation between total EAT‐26 score and total number of Control Options selected, with only elevated scores on a measure of obsessions and compulsivity (OCI‐R) correlating with the total number of Control Options selected (rs = .155, p = .036).DiscussionIn our novel paradigm, we find no relationship between EAT‐26 score and control‐seeking. However, we do find some evidence that this behavior may be present in other disorders that often coincide with ED diagnosis, which may indicate that transdiagnostic factors such as compulsivity are important to control‐seeking.
Green marketing practices and green consumer behavior: Demographic differences among young consumers
Authors: Mehraj Danish , Qureshi Ishtiaq Hussain , Singh Gurmeet , Nazir Nazir Ahmed , basheer Shakeel , Nissa Viqar u 
Published: June 2023

AbstractThe research was undertaken to study the influence of demographics, especially gender, age, education, and income, on the green purchase decisions of Indian consumers. The structured close‐ended questionnaire was distributed among millennials (graduate, post‐graduate, and doctorate students) in educational institutions in the UT of Jammu and Kashmir. A total of 700 students participated in this study employing stratified random sampling. ANOVA and t‐tests were used to analyze the data. The study results show that education and income significantly influence while Age and gender do not significantly influence the green consumer behavior of young Indian consumers. The insights in this study will be helpful to green marketers as they develop strategies for Indian consumers of various genders, age groups, educational backgrounds, occupations, and socioeconomic levels. Future academics and researchers might adopt this work as a starting point to further explore the idea of green marketing in India.
Gen Z's personalization paradoxes: A privacy calculus examination of digital personalization and brand behaviors
Authors: McKee Kathleen M. , Dahl Andrew J. , Peltier James W. 
Published: June 2023

AbstractEmploying privacy calculus theory, we examine why Gen Z consumers increasingly adopt ad blockers, use private browsers, or take other measures to limit data tracking. Specifically, we evaluate consumer behaviors related to personalized and non‐personalized digital marketing in light of two personalization paradoxes: privacy–benefits and avoidance–annoyance. Using structural equation modeling on a sample of 414 Gen Z consumers, our findings show that both the privacy–benefits paradox and avoidance–annoyance paradox strongly influence consumers' intentions to avoid brands that fail to personalize marketing efforts. We also explore the interaction effects of the two digital personalization tensions, showing that tradeoffs exist between the utilization of these two paradoxes. Our findings underscore key implications for marketers investing in personalized marketing efforts to enhance consumer–brand relationships.
Protective Effect of Cannabidiol on Hydrogen Peroxide‐Induced Oxidative Damage in Human Umbilical Vein Endothelial Cells (HUVECs)
Authors: Li Hang , Yang Tian‐Xiao , Zhao Qing‐Sheng , Zhao Bing 
Published: June 2023

AbstractNatural antioxidants play an important role in promoting good health because of their prevention for oxidative damage. The work aimed to explore the antioxidant mechanism and activity of cannabidiol (CBD) at the cellular level. The human umbilical vein endothelial cell (HUVEC) with oxidative damage was employed as the model to study the protective capability of CBD. The results showed that CBD pre‐treatment before the cells were exposed to hydrogen peroxide (H2O2) resulted in an obvious increase of cell viability (about 100 %) and antioxidant related enzymes activity, and a decline of malondialdehyde (MDA) level. Besides, CBD could alleviate the increase of intracellular reactive oxygen species (ROS) content, the contraction of nucleus, and condensation of chromatin. The changes showed a dose‐dependent effect. Additionally, the free radicals scavenging capacity of CBD was comparable to that of typical natural antioxidant, anthocyanidins. In summary, CBD could be employed as a potent antioxidant source for avoiding the oxidative damage. These results could provide the foundation for the development of CBD antioxidant products.
Synthesis, Antifungal Activity, and Molecular Simulation Study of L–Carvone‐Derived 1,3,4‐Oxadiazole‐Thioether Compounds
Authors: Wen Rongzhu , Duan Wengui , Lin Guishan , Li Baoyu , Zhang Zhaolei , Liu Chuwen 
Published: June 2023

AbstractTo discover potent antifungal molecules with new and distinctive structures, 20 novel L‐carvone‐derived 1,3,4‐oxadiazole‐thioether compounds5 a–5 twere synthesized through multi‐step reaction of L‐carvone, and their structures were confirmed by FT‐IR,1H‐NMR,13C‐NMR, and HR‐MS. The antifungal activities of compounds5 a–5 twere preliminarily tested by in vitro method, and the results indicated that all of the title compounds displayed certain antifungal activities against the eight tested plant fungi, especially forP. piricola. Among them, compound5 i(R=p‐F) with the most significant antifungal activity deserved further study for discovering and developing novel natural product‐based antifungal agents. Moreover, two molecular simulation technologies were employed for the investigation of their structure–activity relationships (SARs). Firstly, a reasonable and effective 3D‐QSAR model was established by the comparative molecular field (CoMFA) method, and the relationship of the substituents linked with the benzene rings and the inhibitory activities of the title compounds againstP. piricolawas elucidated. Then, the binding mode of compound5 i(R=p‐F) and its potential biological target (CYP51) was simulated by molecular docking, and it was found that compound5 icould readily bind with CYP51 in the active site, and the ligand‐receptor interactions involved three hydrogen bonds and several hydrophobic effects.
Molecular Highway Patrol for Ribosome Collisions
Authors: Iyer Kaushik Viswanathan , Müller Max , Tittel Lena Sophie , Winz Marie‐Luise 
Published: June 2023

AbstractDuring translation, messenger RNAs (mRNAs) are decoded by ribosomes which can stall for various reasons. These include chemical damage, codon composition, starvation, or translation inhibition. Trailing ribosomes can collide with stalled ribosomes, potentially leading to dysfunctional or toxic proteins. Such aberrant proteins can form aggregates and favor diseases, especially neurodegeneration. To prevent this, both eukaryotes and bacteria have evolved different pathways to remove faulty nascent peptides, mRNAs and defective ribosomes from the collided complex. In eukaryotes, ubiquitin ligases play central roles in triggering downstream responses and several complexes have been characterized that split affected ribosomes and facilitate degradation of the various components. As collided ribosomes signal translation stress to affected cells, in eukaryotes additional stress response pathways are triggered when collisions are sensed. These pathways inhibit translation and modulate cell survival and immune responses. Here, we summarize the current state of knowledge about rescue and stress response pathways triggered by ribosome collisions.
Renal impairment and mortality in patients with STEMI and cardiogenic shock/cardiac arrest
Authors: Shroff Gautam R. , Garcia Santiago , Schmidt Christian , Okeson Brynn , Tannenbaum Edward , Pacheco Roberto , Smith Timothy D. , Garberich Ross , Sharkey Scott , Aguirre Frank , Tannenbaum Mark , Shivapour Daniel , Coulson Teresa , Henry Timothy D. 
Published: June 2023

AbstractObjectivesWe sought to study the association of renal impairment (RI) with mortality in ST‐segment elevation myocardial infarction (STEMI) complicated by cardiogenic shock and/or cardiac arrest (CS/CA).MethodsPatients with RI (estimated glomerular filtration rate <60 mL/min/1.73 m2) were identified from the Midwest STEMI consortium, a prospective registry of four large regional programs comprising consecutive patients over 17 years. Primary outcome was in‐hospital and 1‐year mortality stratified by RI status and presence of CS/CA among patients with STEMI referred for coronary angiography.ResultsIn a cohort of 13,463 STEMI patients, 13% (n = 1754) had CS/CA, 30% (n = 4085) had RI. Overall, in‐hospital mortality was 5% (12% RI vs. 2% no‐RI, p < 0.001) and 1‐year mortality 9% (21% RI vs. 4% no‐RI, p < 0.001). Among uncomplicated STEMI, in‐hospital mortality was 2% (4% RI vs. 1% no‐RI, p < 0.001) and 1‐year mortality 6% (13% RI vs. 3% no‐RI, p < 0.001). In STEMI with CS/CA, in‐hospital mortality was 29% (43% RI vs. 15% no‐RI, p < 0.001) and 1‐year mortality 33% (50% RI vs. 16% no‐RI, p < 0.001). Using Cox proportional hazards, RI was an independent predictor of in‐hospital mortality in STEMI with CS/CA (odds ratio [OR]: 3.86; confidence interval [CI]: 2.6, 5.8).ConclusionsThe association of RI with in‐hospital and 1‐year mortality is disproportionately greater in those with CS/CA compared to uncomplicated STEMI presentations. Factors predisposing RI patients to higher risk STEMI presentations and pathways to promote earlier recognition in the chain of survival need further investigation.
Annular pustular crusted plaques as unusual cutaneous presentation of systemic lupus erythematosus
Authors: Gheisari Mehdi , Baghani Moein , Ganji Raziyeh , Zahedi Khatere 
Published: June 2023

Key Clinical MessageSystemic lupus erythematosus (SLE) is a systemic autoimmune disease that affects several organs including the skin. Clinical cutaneous symptoms of SLE come in a broad range, consisting of both non‐specific and specific cutaneous lesions. Except for cases of amicrobial pustulosis of the folds, generalized pustular psoriasis, acneiform eruptions, pustular vasculitis, Wells' syndrome, subcorneal pustular dermatosis, and neutrophilic dermatosis, there are no reports of pustular lesions linked to SLE. The unusual cutaneous features of our patient were annular plaques with pustules and crusts on the margins.
Tumoral calcinosis in the extensor indicis proprius tendon: A case report
Authors: AlShamsi Maithaa , AlDhamin Ammar 
Published: June 2023

Key Clinical MessageTumoral calcinosis is a rare clinicopathological entity characterized by the presence of calcified deposits in the periarticular soft tissue. Commonly affecting the hips, buttock, shoulders, and elbow, and less commonly in hands, wrists, and feet. We present a novel case of tumoral calcinosis in a 4‐year‐old female with an atraumatic wrist swelling for 2 months. It was a diagnostic enigma for the surgeon due to the peculiar site of presentation. However, with the help of a pathologist, we diagnosed and successfully treated tumoral calcinosis of the extensor indicis proprius tendon.
Imatinib associated temporal bone osteonecrosis
Authors: McKenna Dominic , Reddy Ekambar 
Published: June 2023

Key Clinical MessageTyrosine kinase inhibitors have substantially improved survival in patients with gastrointestinal stromal tumors (GIST) and chronic myeloid leukemia (CML). We report the first association between long‐term imatinib use and temporal bone osteonecrosis, highlighting the importance of prompt ENT evaluation of such patients with new otological symptoms.
Spatiotemporal Investigation of Intercellular Heterogeneity via Multiple Photocaged Probes
Authors: Tsai Chun‐Yi , Chen Po‐Hsun , Chen Ai‐Lin , Wang Tsung‐Shing Andrew 
Published: June 2023

AbstractIntercellular heterogeneity occurs widely under both normal physiological environments and abnormal disease‐causing conditions. Several attempts to couple spatiotemporal information to cell states in a microenvironment were performed to decipher the cause and effect of heterogeneity. Furthermore, spatiotemporal manipulation can be achieved with the use of photocaged/photoactivatable molecules. Here, we provide a platform to spatiotemporally analyze differential protein expression in neighboring cells by multiple photocaged probes coupled with homemade photomasks. We successfully established intercellular heterogeneity (photoactivable ROS trigger) and mapped the targets (directly ROS‐affected cells) and bystanders (surrounding cells), which were further characterized by total proteomic and cysteinomic analysis. Different protein profiles were shown between bystanders and target cells in both total proteome and cysteinome. Our strategy should expand the toolkit of spatiotemporal mapping for elucidating intercellular heterogeneity.
Peptide Assemblies for Cancer Therapy
Authors: Qiao Yuchen , Xu Bing 
Published: June 2023

AbstractSupramolecular assemblies made by the self‐assembly of peptides are finding an increasing number of applications in various fields. While the early exploration of peptide assemblies centered on tissue engineering or regenerative medicine, the recent development has shown that peptide assemblies can act as supramolecular medicine for cancer therapy. This review covers the progress of applying peptide assemblies for cancer therapy, with the emphasis on the works appeared over the last five years. We start with the introduction of a few seminal works on peptide assemblies, then discuss the combination of peptide assemblies with anticancer drugs. Next, we highlight the use of enzyme‐controlled transformation or shapeshifting of peptide assemblies for inhibiting cancer cells and tumors. After that, we provide the outlook for this exciting field that promises new kind of therapeutics for cancer therapy.