bluuebunny/crossref_metadata_2025_split huggingface dataset:
«Зоопарк» эмпирических результатов: количественные исследования и прирост знания об обществе
Authors: Либман А.М. 
Published: January 2025

Последние десятилетия стали периодом «эмпирического поворота» в экономической науке и во многом в других общественных науках — растущей роли количественных эмпирических исследований и снижения влияния больших исследовательских программ и парадигм. Однако что означает рост числа эмпирических исследований для общего процесса накопления знания об обществе? В принципе генерализируемость выводов часто рассматривается как важное преимущество количественных методов. В статье показано, что стандартные исследования «эмпирического поворота» лишь в небольшой степени вступают в диалог друг с другом, опираются друг на друга или пытаются опровергнуть друг друга. Ссылки на другие статьи часто имеют символический характер. Вместо стройной систематической картины мира формируется своего рода «зоопарк» бесчисленных исследований, отдельных «кейсов», слабо связанных друг с другом. Такое развитие, однако, не обязательно следует воспринимать как признак кризиса науки.
The last decade became a period of an empirical turn in economics and in many other social sciences, i. e., increasing role of quantitative empirical research and declining importance of big paradigms and research programs. What does, however, the increase of the number of empirical studies mean for the overall accumulation of knowledge about societies? Fundamentally, generalizable results are frequently seen as an important advantage of the quantitative methods. However, our article shows that standard studies within the framework of the empirical turn hardly communicate with each other, build upon each other or try to refute each other. References to other papers play a more or less symbolic role. Instead of a systematic worldview a sort of a ‘zoo’ of numerous individual case studies emerges, being hardly connected to each other. This development, however, should not necessarily be perceived as evidence of a crisis in social sciences.
Является ли Российское государство патерналистским? (К вопросу о концепции А. Я. Рубинштейна)
Authors: Оболонский А.В. 
Published: January 2025

Статья посвящена обсуждению части вопросов, поднимаемых в фундаментальной междисциплинарной работе А. Я. Рубинштейна. Отмечаются многие достоинства статьи, ее глубокий, стимулирующий к размышлениям и дальнейшему развитию идей характер. Это предполагает дискуссию по ряду вопросов. Поднимаемые автором вопросы о сущности и типах государства, о его роли в жизни человека относятся к числу «вечнозеленых». Их историческую эволюцию я обозначил очень кратким обзором. А основная часть статьи посвящена дискуссии относительно интерпретации автором взглядов фон Хайека, а также различиям в понимании автором статьи и мной концепта патерналистского государства. Представляется, что Рубинштейн недооценивает либеральную основу социальных взглядов Хайека и в то же время неоправданно расширительно трактует само понятие патерналистского государства. В результате этого оно, по сути, распространяется на всякое авторитарное правление, что представляется не вполне корректным. Это я и пытаюсь аргументированно показать на исторических и современных примерах. Отдельный интерес представляют социологическая часть статьи и авторское описание провалов современного российского государства, дающее ценный материал для дальнейших аналитических рассуждений и исследований.
The article is devoted to discussion around a part of questions, raised in the fundamental interdisciplinary work by A.Ya. Rubinshtein. Multiple qualities of his article, a deep character of it, stimulating to further considerations and development of its ideas, are emphasized. It assumes, at the same time, discussion on some aspects of it. Problems of the essence and typology of states, its place in the life of individual are everlasting and “evergreen”. I reminded the historical evolution of them in a very short review. The major part of my arguments was addressed to analysis of the author’s interpretation of von Hayek’s views and to critical comparison of his and my understandings of paternalistic state. It seems that Rubinshtein underestimates the liberal basis of Hayek’s social vision. He interprets paternalistic state unreasonably too broadly. As a result, this notion becomes almost similar to any authoritarian rule. That seems to me incorrect, and I am trying to prove it on historical and contemporary examples. Sociological part of the article is of special interest, including the author’s description of states’ failures attributed to contemporary Russia. It presents a valuable ground for the following analytical considerations and research.
Государство: хищническая природа против гражданского общества
Authors: Заостровцев А.П. 
Published: January 2025

В статье представлен взгляд на хищническую природу государства как на его универсальное свой ство. Она противостоит как рынкам, так и гражданскому обществу. Однако если в определение государства включить рынки и гражданское общество, то это будет идеологическим оправданием поглощения их государством. Государство рассматривается как стремящееся к постоянному разрастанию за счет вытеснения независимых от него институтов и превращению, в конечном счете, во всеохватывающий институт. Кратко анализируются опросы российских экспертов в отношении политического участия, гражданских прав и т. д. Делается вывод о том, что на их основе можно утверждать наличие промежуточного состояния российского государства, находящегося между неопатримониализмом и неосултанизмом. Возрождение же гражданского общества через развитие социальных сетей не видится в качестве реальной перспективы по причине преимуществ госу- дарства как центрального актора цифрового мира и носителя права на легитимное насилие. Ключевые слова: хищническое государство, гражданское общество, властнособственническое общество, неопатримониальное государство, неосултанистское государство, социальные сети.
The article presents the predatory nature of the state as its universal property. It opposes both markets and civil society. However, if markets and civil society are included in the definition of the state, this will be an ideological justification for their absorption by the state. The government is viewed as striving for constant expansion by reducing civil institutions and ultimately turning the latter into state institution. The surveys of russian experts on political participation, civil rights etc. are briefly analyzed. It is concluded that one can assert that the Russian state is in an intermediate position, located between neopatrimonialism and neosultanism. The revival of civil society through the development of social networks is not seen as a real prospect due to the advantages of state as central actor in the digital world and the bearer of right to legitimate violence.
Pengaruh Komunikasi Interpersonal Dalam Pemahaman Terkait Pemilahan Sampah di SDN 09 Sungai Cubadak
Authors: Adi Putri Silvia , Soni Redha Pratiwi , Adzkia Legabina , Setiana Iffa 
Published: January 2025

Abstrak: Kegiatan Pengabdian Masyarakat (PKM) ini dilaksanakan di SDN 09 Sungai Cubadak,Baso , Kabupaten Agam pada Tanggal 12 September – 13 September 2024. Kegiatan ini mengiktsertakan Sejumlah Siswa di SDN 09 Sungai Cubadak. Kegiatan ini bertujuan untuk meningkatkan kompetensi Siswa terkait komunikasi interpersonal dan pemilahan sampah, Sosialisasi tentang penerapan pemilahan sampah di SDN 09 Sungai Cubadak,Baso , Kabupaten Agam. Kegiatan PKM ini telah disesuaikan dengan fokus ilmu dan kajian dari program studi D-III Administrasi Rumah Sakit dan Dosen yang melakukan pengabdian masyarkat ini telah sesuai dengan bidang ilmu serta Visi dan MIsi Program Studi. Pelaksanaan PKM Bertujuan untuk Meningkatkan kompetensi Siswa terkait komunikasi interpersonal dan pemilahan sampah.
Pengaruh Kualitas Produk dan Promosi terhadap Keputusan Pembelian Sepeda Motor Nmax di Dealer Yamaha Jayamandiri Gemasejati Bojong Gede Kabupaten Bogor
Authors: Muzakir Abdul Wahid , Apriliani Siti 
Published: January 2025

Tujuan penelitian ini untuk mengetahui Pengaruh Kualitas Produk dan Promosi Terhadap Keputusan Pembelian Sepeda Motor Nmax Di Dealer Yamaha Jayamandiri Gemasejati Bojong Gede Kabupaten Bogor secara parsial dan simultan. Metode penelitian yang digunakan ialah metode kuantitatif dengan pendekatan assositaif. Sumber data populasi pada penelitian ini sebanyak 230, teknik sampling dalam penelitian ini menggunakan rumus slovin dengan margin error 5%. Jumlah sampel yang diperoleh berjumlah 146 orang dan pengumpulan data dilakukan menggunakan kuesioner dengan mengacu pada skala likert. Teknik analisis data menggunakan uji instrumen data, uji asumsi klasik, uji kuantitatif dan uji hipotesis dengan SPSS 27. Uji hipotesis parsial kualitas produk diperoleh nilai Thitung ≥ Ttabel (thitung 12,175 ≥ ttabel 1,656) atau nilai Sig (0,000 ≤ 0,05) maka H0 ditolak dan H1 diterima, yang artinya variabel kualitas produk secara parsial berpengaruh signifikan terhadap keputusan pembelian. Uji hipotesis parsial promosi diperoleh nilai Thitung ≥ Ttabel (thitung 9,065 ≥ ttabel 1,656) atau nilai Sig (0,000 ≤ 0,05) maka H0 ditolak dan H2 diterima, yang artinya variabel promosi secara parsial berpengaruh signifikan terhadap keputusan pembelian. Kualitas Produk (X1) dan Promosi (X2) secara simultan berpengaruh positif dan signifikan terhadap kepuasan pelanggan (Y) yang dibuktikan dari hasil persamaan regresi linier berganda Y= 30,957 + 0,227 (X1) + 0,031 (X2) + ie dan nilai Fhitung ≥ Ftabel (Fhitung 129,337 > Ftabiel 1,656) atau nilai sig (0,000b < 0,05) maka H0 ditiolak dan H3 ditierima, nilai koefisien determinasi sebesar 64,4% sedangkan sisanya 35,6% dipengaruhi oleh faktor lain.
Pengaruh Current Ratio dan Debt to Equity Ratio terhadap Return on Equity pada PT Telekomunikasi Indonesia (Persero) Tbk Periode 2012 - 2021
Authors: Ariyanti Fitri , Astutik Endang Puji 
Published: January 2025

Penelitian ini dilakukan bertujuan untuk menguji pengaruh Current Ratio (CR), Debt to Equity Ratio (DER), terhadap Return On Equity (ROE) pada perusahaan PT Telekomunikasi Indonesia (Persero) Tbk. Penelitian ini menggunakan metode deskriptif kuantitatif dengan sampel sebanyak 10 tahun yaitu berupa laporan keuangan tahunan periode 2012-2021. Analisis data yang digunakan yaitu analisis regresi linier berganda, uji hipotesis menggunakan uji t, uji f, dan uji determinasi. Hasil dalam penelitian ini menunjukkan bahwa Current Ratio (CR) berpengaruh positif dan signifikan secara parsial terhadap Return On Equity (ROE) dengan nilai thitung 2,994 > 2,365 ttabel dan memiliki nilai signifikansi 0,017 < 0,05 dan Debt to Equity Ratio (DER) berpengaruh negatif dan signifikan secara parsial terhadap Return On Equity (ROE) dengan nilai thitung -3,931 > 2,365 ttabel dan memiliki nilai signifikansi 0,004 < 0,05. Secara simultan Current Ratio (CR) dan Debt to Equity Ratio (DER) berpengaruh positif dan signifikan terhadap Return On Equity (ROE) dengan nilai signifikansi 0,017 < 0,05 dengan nilai fhitung 7,626 > ftabel 4,74. Pada PT Telekomunikasi Indonesia (Persero) Tbk. Koefisien Determinasi (R Square) menunjukkan bahwa diketahui nilai koefisien determinasi variabel Current Ratio dan Debt to Equity Ratio terhadap Return On Equity sebesar 68,5%. Sedangkan sisanya yaitu sebesar 31,5% dipengaruhi oleh variabel lain.
Pengaruh Kualitas Pelayanan O-Ranger Antaran terhadap Kepuasan Pelanggan pada PT. Pos Indonesia Rangkasbitung 42300
Authors: Anggraeni Angga Dewi , Nuraeni Beti Siti 
Published: January 2025

Keberhasilan suatu perusahaan dapat dilihat dari kemampuan perusahaan dalam memberikan pelayanan kepada pelanggan, pelayanan yang berkualitas dapat memberikan kepuasan kepada pelanggan dan perusahaan dapatmeningkatkan nilai pada perusahaan. Hal tersebut dapat menjadi pengaruh kualitas pelayanan oranger antaran terhadap kepuasan pelanggan pada PT. Pos Indonesia. Metode penelitian ini menggunakan metode deskriptif kuantitatif dan menggunakan objek penelitian Kualitas Pelayanan dan Kepuasan Pelanggan. Dalam penelitian ini data yang digunakan bersumber data primer dan data sekunder. Populasi dari penelitian ini merupakan data dari pelanggan yang datang ke PT. Pos Indonesia Kota Rangkasbitung. Pengambilan sampel menggunakan sampling Insedintial dan pengumpulan datanya menggunakan kuisioner. Serta teknik analisis data yang digunakan adalah uji validitas, reliabilitas dan analisis linear sederhana dengan menggunakan program SPSS serta melakukan uji hipotesis dengan melakukan uji T. Populasi yang digunakan dalam penelitian ini sebanyak 6,130, dan sampel yang digunakan sebanyak 99 pelanggan. Dalam penelitian ini kualitas pelayanan memiliki pengaruh sebesar 67,7% terhadap kepuasan pelanggan, sedangkan 32,3% lainnya dipengaruhi variabel lain
Pengaruh Strategi Pembelajaran Bernyanyi Terhadap Perkembangan Kemampuan Membaca Anak Usia 5-6 Tahun
Authors: Cahyani Nurul , Dorlina Simatupang Nurhenti , Reza Muhammad , Widayati Sri 
Published: January 2025

Kemampuan membaca adalah salah satu komponen pendidikan yang paling penting dan berfungsi sebagai bakat dasar yang harus dimiliki setiap individu. Pembelajaran justru lebih mudah diterima oleh anak pada masa golden age. Mulai membaca sejak usia dini merupakan bakat yang perlu dimiliki setiap anak karena memungkinkan mereka untuk mengikuti pelajaran di sekolah dan membuka dunia pengetahuan serta kesempatan untuk meraih keberhasilannya. Penelitian ini mengerucut dan fokus pada pengaruh strategi pembelajaran bernyanyi dengan tahapan terhadap perkembangan kemampuan bahasa khusunya membaca. Desain yang digunakan dalam penelitian ini adalah desain penelitian quasi-exsperimental atau eksperimen semu dengan nonequivalent control group design menggunakan uji Mann Whitney U Test menunjukkan hasil nilai nilai U < U tabel, maka Ha diterima dan Ho ditolak. Artinya pada penelitian ini terdapat perbedaan secara signifikan antara kelompok eksperimen dan kelompok kontrol setelah perlakuan. Dalam hal ini dapat diartikan bahwa strategi pembelajaran bernyanyi memiliki pengaruh terhadap kemampuan membaca permulaan pada anak. Hipotesis diterima.
Abating Heat Accrual During Exercise in Microgravity and Implications for Future Long-Term Missions
Authors: Maguire Katherine , Wydotis Margaret , Bollinger Lance , Caruso John 
Published: January 2025

INTRODUCTION: Space agencies will embark on manned journeys to Mars on smaller vehicles than those used previously. In-flight exercise on those flights must abate the adverse effects microgravity (μG) has on humans. Due to space constraints on these vehicles, a single exercise device must address multiple fitness needs. Exercise and μG individually cause body heat accrual. During in-flight exercise they conspire to exacerbate heat gain. Given the duration of Mars missions and volume of exercise they entail, excess heat accrual must be addressed.
METHODS: This review presents data on μG, thermoregulation, and exercise. Since their relationships are impacted by other variables, energy balance, body water, and cerebral and vascular physiology are discussed. Data are integrated to acknowledge the challenges long-term missions, and the in-flight exercise that accompanies them, impose on thermoregulation. Strategies to limit heat accrual are discussed.
RESULTS: Current in-flight exercise and hardware will not address heat accrual mitigation or operational performance needs for Mars missions.
DISCUSSION: This review suggests for future missions, crewmembers: 1) consume beverages with high sodium contents; 2) employ palm cooling for conductive heat transfer; and 3) perform plyometric exercise on gravity-independent hardware. Research should continue to evaluate these treatments to abate heat gain in μG.
Maguire K, Wydotis M, Bollinger L, Caruso J. Abating heat accrual during exercise in microgravity and implications for future long-term missions. Aerosp Med Hum Perform. 2025; 96(1):53–61.
Enhancement of host defense against Helicobacter pylori infection through modulation of the gastrointestinal microenvironment by Lactiplantibacillus plantarum Lp05
Authors: Dong Yao , Han Mei , Qi Yongmei , Wu Ying , Zhou Zhipeng , Jiang Dacheng , Gai Zhonghui 
Published: January 2025

ObjectiveThis study aimed to assess the impact of Lactiplantibacillus plantarum Lp05 (Lp05) on the gastrointestinal microbiome and pathophysiological status of mice infected with Helicobacter pylori (H. pylori), exploring its potential as a probiotic treatment for H. pylori infections.MethodsIn vitro, the interaction between Lp05 and H. pylori was analyzed using laser confocal and scanning electron microscopy. In vivo, C57BL/6 mice infected with H. pylori were treated with Lp05 and divided into six groups: control, model, quadruple therapy, and three dosage levels of Lp05 (2×107, 2×108, 2×109 CFU/mouse/day). Over six weeks, the impact of Lp05 on the gastrointestinal microbiome and physiological markers was assessed. Measurements included digestive enzymes (α-amylase, pepsin, cellulase), inflammatory markers (interleukin-17A, interleukin-23, interleukin-10, interferon-β, interferon-γ, FoxP3, endothelin, IP-10, TGF-β1), oxidative stress markers (catalase, malondialdehyde, superoxide dismutase, myeloperoxidase), and tissue pathology (via modified Warthin-Starry silver and H&amp;E staining). Microbial community structure in the stomach and intestines was evaluated through 16S rRNA gene sequencing.ResultsIn vitro studies showed Lp05 and H. pylori formed co-aggregates, with Lp05 potentially disrupting H. pylori cell structure, reducing its stomach colonization. In vivo, Lp05 significantly lowered gastric mucosal urease activity and serum H. pylori-IgG antibody levels in infected mice (p &lt; 0.01). It also mitigated pathological changes in the stomach and duodenum, decreased inflammatory responses (ET, IL-17A, IL-23, TGF-beta1, and IP-10, p &lt; 0.01 for all), and enhanced antioxidant enzyme activities (CAT and SOD, p &lt; 0.01) while reducing MDA and MPO levels (p &lt; 0.01), combating oxidative stress from H. pylori infection. Lp05 treatment significantly modified the intestinal and gastric microbiota, increasing beneficial bacteria like Lactobacillus and Ligilactobacillus, and decreasing harmful bacteria such as Olsenella, linked to pathological conditions.ConclusionLp05 effectively modulates the gastrointestinal microbiome, reduces inflammation and oxidative stress, and suppresses H. pylori, promising for probiotic therapies with further research needed to refine its clinical use.
Salivary proteomics profiling reveals potential biomarkers for chronic kidney disease: a pilot study
Authors: Picolo Bianca Uliana , Silva Nathália Rabello , Martins Mário Machado , Almeida-Souza Hebréia Oliveira , de Sousa Letícia Cristina Machado , Polveiro Richard Costa , Goulart Filho Luiz Ricardo , Sabino-Silva Robinson , Alonso-Goulart Vivian , Saraiva da Silva Luciana 
Published: January 2025

IntroductionChronic kidney disease (CKD) is a global public health problem, and the absence of reliable and accurate diagnostic and monitoring tools contributes to delayed treatment, impacting patients’ quality of life and increasing treatment costs in public health. Proteomics using saliva is a key strategy for identifying potential disease biomarkers.MethodsWe analyzed the untargeted proteomic profiles of saliva samples from 20 individuals with end-stage kidney disease (ESKD) (n = 10) and healthy individuals (n = 10) using liquid chromatography–tandem mass spectrometry (LC–MS/MS) to identify potential biomarkers for CKD. A volcano plot was generated using a p-value of ≤0.05 and a fold change (FC) ≥ 2.0. Multivariate analysis was performed to generate the orthogonal partial least squares discriminant analysis (OPLS-DA) model and the variable importance in projection (VIP) scores. The accuracy of candidate biomarker proteins was evaluated using receiver operating characteristic (ROC) curves.ResultsIn total, 431 proteins were identified in the salivary proteomic profile, and 3 proteins were significantly different between the groups: apoptosis inhibitor 5 (API5), phosphoinositide phospholipase C (PI-PLC), and small G protein signaling modulator 2 (Sgsm2). These proteins showed good accuracy based on the ROC curve and a VIP score of &gt;2.0. During pathway enrichment, PI-PLC participates in the synthesis of IP3 and IP4 in the cytosol. Gene ontology (GO) analysis revealed data on molecular functions, biological processes, cellular components, and protein classes.ConclusionWe can conclude that the salivary API5, PI-PLC, and Sgsm2 can be potential biomarker candidates for CKD detection. These proteins may participate in pathways related to renal fibrosis and other associated diseases, such as mineral and bone disorders.
Изучение хронической токсичности нового миорелаксанта на белых крысах
Authors: Ямалова Г.Р. 
Published: January 2025

Для отлова животных применяют миорелаксанты периферического действия, которые отличаются по составу, механизму действия, способности расслаблять различные группы мышц, также по эффективности воздействия при разных способах введения. В отделении токсикологии ФГБНУ «ФЦТРБ-ВНИВИ» получен препарат с миорелаксирующим действием. Важным этапом доклинической оценки безопасности нового лекарственного препарата является изучение его хронической токсичности, направленное на выявление возможности обратимости желаемого токсического эффекта, что и определило цель данного исследования. Целью исследования являлось изучение хронической токсичности разработанного миорелаксанта на белых крысах. Хроническую токсичность оценивали на 36 беспородных белых крысах обоего пола, весом от 170 до 220 г. Всего было сформировано три группы животных. Животным первой контрольной группы внутримышечно вводили воду для инъекций, второй – 1/10 смертельной дозы (ЛД50) миорелаксант (0,26 мг/кг массы тела), третьей – полуторакратную дозу от 1/10 ЛД50 препарата, что соответствовало 0,39 мг/кг массы тела. Результаты исследований продемонстрировали, что парентеральное длительное введение миорелаксанта не оказывает существенного влияния на массу и температуру тела лабораторных животных, не вызывает негативного воздействия на гематологические и биохимические показатели крови белых крыс. Таким образом, препарат с миорелаксирующим действием не обладает хронической токсичностью при длительном введении белым крысам.
For trapping animals, peripheral muscle relaxants are used, which differ in composition, mechanism of action, ability to relax various muscle groups, as well as in the effectiveness of exposure with different methods of administration. A drug with a muscle relaxant effect was developed in the Department of Toxicology of the FSBSI «FCTRBS-ARRVI». An important stage in the preclinical evaluation of the safety of a new drug is the study of its chronic toxicity, aimed at identifying the possibility of reversibility of the desired toxic effect, which determined the purpose of this study. The aim of the reserach was to study the chronic toxicity of the developed muscle relaxant in white rats. Chronic toxicity was evaluated on 36 outbred white rats of both sexes, weighing from 170 to 220 g. In total, three groups of animals were formed. The animals of the first control group were intramuscularly administered with water for injections, the second - 1/ 10 of the lethal dose (LD50) of muscle relaxant (0.26 mg/kg of body weight), the third - a one-and-a half dose of 1/10 LD 50 of the drug, which corresponded to 0.39 mg/kg of body weight. The results of the studies demonstrated that parenteral long-term administration of a muscle relaxant neither significantly affected the body weight and temperature of laboratory animals, nor caused a negative effect on hematological and biochemical parameters of the blood of white rats. Thus, the drug with a muscle relaxant effect does not have chronic toxicity when administered for a long time to white rats.