bluuebunny/crossref_metadata_2025_split huggingface dataset:
The water–energy–food–land–climate nexus: Policy coherence for sustainable resource management in Sweden
Authors: Blicharska Malgorzata , Smithers Richard J. , Kuchler Magdalena , Munaretto Stefania , van den Heuvel Lotte , Teutschbein Claudia 
Published: August 2023

AbstractThe concept of a ‘nexus’ across issues regarding the management of natural resources has gained increasing academic attention in recent years, but there is still relatively limited research on the application of the nexus approach for evaluating policies. This study analyses coherence among the main goals of five policy areas (water, energy, food, land, and climate) in Sweden, drawing upon a desk review, expert assessment, and interaction with stakeholders. The main objective is to enhance understanding of opportunities and challenges posed by such a nexus, understand policy interactions in Sweden, and provide insights into the use of policy coherence analysis as an integral part of resource nexus assessments. The analysis reveals synergies and conflicts between policy goals. For example, Sweden's environmental quality objectives (EQOs) regarding land and all the goals regarding water are either synergistic or neutral. Likewise, climate policy goals are well aligned with the goals regarding energy and ground water quality. On the other hand, the key goal for agriculture, which is food production, is the least coherent with those of the other policy areas. There are conflicts between the EQOs and goals regarding agricultural and forestry production. Stakeholders also indicate that climate goals are treated with higher priority than the goals of other policy areas. Notably, some interactions between policy goals are synergistic or conflicting depending on the context or their interpretation. Implementation of existing goals depends on relevant stakeholders' interests, priorities and interpretations, and on existing prevailing discourses in society, often supported by higher level policies.
Photoinduced Oxygen Atom Transfer to α‐Pinene and R‐Carvone using a Dioxo‐Molybdenum (VI) Complex Incorporated within a Modified UiO‐67 (Zr/Ti) MOF
Authors: Valdivieso Zarate Laura M. , Bravo Sanabria Cesar A. , Ramírez Caballero Gustavo E. , Martínez Ortega Fernando 
Published: August 2023

AbstractWe report a highly selective (100 %) epoxidation of α‐pinene and R‐carvone using an oxygen atom transfer (OAT) reaction facilitated by a dioxo‐Mo complex (Mo(VI)O2Cl2Ln) incorporated into the ligand 5,5’‐dicarboxylate‐2,2’‐bipyridine (bpydc) within a Metal‐Organic Framework (MOF) type UiO‐67. Photo‐stimulated (350 nm) OAT reaction was carried out with oxygen molecular used as the oxidant for 10 h. UiO‐67 was synthesized with a mixture of the ligands 2,2′‐biphenyl‐5,5′‐dicarboxylate (bpdc) and 2,2‐bipyridine‐5,5‐dicarboxylate (bpydc) in different molar ratios (67 : 33, 50 : 50, 70 : 30, 0 : 100 bpdc : bpydc) to promote a higher presence of catalytic sites, i. e., the dioxo‐Mo complex units. Furthermore, a post‐synthetic exchange of Zr for Ti, between 64 : 36 to 78 : 22 Ti : Zr molar ratio, was performed to improve the optical properties of the MOF and promote the photoinduced OAT reaction. The Catalytic system was characterized by FTIR, XRD, 1H NMR, XPS, TGA, N2 adsorption/desorption and UV‐Vis‐DR. The amount of the epoxide monoterpene is proportional to the number of the dioxomolybdenum(VI) units (MoO2) incorporated in the UiO‐67 (Zr/Ti), and the OAT reaction selectivity is due to the absence of the oxygen radicals in the medium of reaction. Besides, The Mo complex exhibited excellent stability after five cycles of use.
A Fluorescent Probe for Al3+ Based on Calix[4]arene Containing Salicylaldehyde‐Derived Schiff Base
Authors: Wang Zuquan , Li Yunjian , Shi Jing , Sun Xiaoqiang , Xiao Tangxin , Yang Ke , Li Zheng‐Yi 
Published: August 2023

AbstractTwo novel fluorescent probes L1 and L2 for recognizing Al3+ have been prepared by cooperating salicylaldehyde‐derived Schiff base groups onto the upper rim of the calix[4]arene. Of these probes, L2 is the most effective at recognizing Al3+, displaying a highly selective fluorescence “on” response with an emission wavelength at 478 nm and a Stokes shift of 88 nm. Additionally, probe L2 can form a 1 : 1 coordination complex with Al3+ with a binding constant of 2.6×1010 M−1. Furthermore, its fluorescence intensity exhibits a good linear relationship with Al3+ concentration within the range of 2.0×10−5 M to 1.4×10−4 M, and the probe has a low detection limit of 4.36×10−7 M.
C,N‐Diarylformamidines as Valuable Building Blocks in the Synthesis of Heterocyclic Compounds
Authors: Trukhanova Yulia A. , Chernov Nikita M. , Kuvaeva Elena V. , Yakovlev Igor P. 
Published: August 2023

AbstractObtaining highly functionalized heterocyclic structures is an important topic of modern organic synthesis, as it reveals the possibility of constructing more complex systems and therefore, expanding the range of various drugs. Aiming at synthesizing complex molecules from simple and readily available reagents, the modification of C,N‐diarylformamidines, well known in medicinal chemistry, is of great interest. This article reviews comprehensively the field of C,N‐diarylformamidine chemistry and covers publications on this topic from 1999 to 2022.
Evaluating the effectiveness of ground motion intensity measures through the lens of causal inference
Authors: Burton Henry V. , Baker Jack W. 
Published: August 2023

AbstractWhen solving the performance‐based earthquake engineering (PBEE) integral, the engineering demand parameters (EDPs) are assumed to be independent of the “upstream” parameters used in ground motion models (e.g., magnitude and source‐to‐site distance) after conditioning on the intensity measure (IM). This paper formulates a methodology for evaluating this conditional independence assumption through the lens of causal inference (CI). From a causal perspective, the effect of an upstream parameter on the EDP of interest is partially mediated by the IM with the remainder having a direct influence on the EDP. An IM is judged to be desirable (from a conditional independence standpoint) if the mediated effect of the upstream parameter is maximized, which implies that the direct effect is minimized. In the language of causal inference (CI), the IM, EDP and upstream parameters are described as the “treatment”, “outcome” and “confounding” variables, respectively. It then follows that the best performing IM is the one that maximizes the effect on the EDP after controlling for the upstream parameters. A semi‐parametric model that employs double machine learning is used to estimate the causal effect. The methodology is demonstrated through a case study application utilizing the responses from five special steel moment frames analyzed using 240 site‐agnostic ground motions. Compared to sufficiency‐based assessments, the casual inference method produces findings that are more explainable using structural dynamics principles and invariant to the number of ground motions used in the evaluation.
Time‐varying partial‐directed coherence approach to forecast global energy prices with stochastic volatility model
Authors: Dhifaoui Zouhaier , Ben Jabeur Sami , Khalfaoui Rabeh , Nasir Muhammad Ali 
Published: August 2023

AbstractFor investors and policymakers, forecasting energy prices with accuracy is essential and plays a major role in the global bulk commodity markets. The current study proposes a novel hybrid forecasting model to predict global energy prices, namely, time‐varying partial‐directed coherence with stochastic volatility. The proposed method combines partial‐directed coherence analysis and stochastic volatility models. Accordingly, this study attempts to provide an in‐depth understanding of the relationship between energy markets and global economic conditions as well as the causality pathway between the underlined markets. Monthly data from January 1982 to July 2022 is used in this study. The results show a strong causality between global economic conditions, European oil, and natural gas prices and have profound implications for policymakers. For completeness, we extend the analysis to the forecasting ability of global economic conditions for oil and natural gas prices. The out‐of‐sample results show that the autoregressive model incorporating the global economic conditions index can significantly improve the accuracy of oil and gas price forecasts. In addition, our results are strongly robust over a variety of time horizons for forecasting, and they provide valuable insights into the forecasting choices to guide investment strategies in the energy and financial market.
Application of the Technology Readiness Levels Framework to Natural Resource Management Tools
Authors: Cupp Aaron , Fritts Andrea , Brey Marybeth , Woodley Christa , Smith David , Cornish Mark , McGovern Amy , Simmonds Rob , Jackson Neal 
Published: August 2023

Abstract
Technology advancements in fisheries science can provide useful tools to support natural resource management and conservation. However, new technologies may also present challenges for decision makers due to the lack of a standardized process to assess technologies for consideration within management plans. Future technology development in fishery and water resources could benefit from a framework that assigns an appropriate technology development stage and defines the readiness for implementation. Technology Readiness Levels (TRL) are one established research and development scale used throughout engineering and related disciplines that could be applied to natural resource management tools. The TRL assess the maturity of a technology from nascent idea through a fully developed technology. Steps within this scale could provide a general framework for researchers to follow when planning and conducting studies, while similarly providing a standard scale for resource managers to assess readiness for technology transfer and implementation. The goal of this paper is to describe TRL in the context of natural resource management tools and offer this existing framework as one option to facilitate communication between researchers and managers.
Evaluation of foam application in providing required conditioning for EPB hard rock TBMs
Authors: Firouzei Yavar , Hassanpour Jafar , Peila Daniele , Azali Sadegh Tarigh , Todaro Carmine 
Published: August 2023

AbstractUtilizing the earth pressure balancing technique on hard rock tunnel boring machines (TBMs) is an efficient way to overcome engineering geological hazards that disrupt the application of these machines. Considering that geomechanical and engineering geological conditions of soil and rock are dramatically different, proposing a suitable conditioning design for earth pressure balance (EPB) hard rock TBMs requires particular attention to the characteristics of the excavated material and ground conditions. In this paper, foam application providing a favourable support medium for EPB hard rock TBMs is evaluated based on the experience of the Tehran metro line 6 southern expansion sector project, using laboratory and actual data. TBM muck, with different water contents, was used as the test specimen after granulometry correction. The trend of changes in the workability of foam conditioned mix was obtained by performing 350 slump tests. The pressurized permeability cell test (PPCT), a testing device capable of applying high water pressures to the conditioned material, was used to evaluate the impermeability of workable mixes. Results indicate that although foam can efficiently increase the workability of dry and moistened specimens, the presence of a separated liquid phase in the test specimen disrupts its application; moreover, foam conditioned mix is permeable even against low water pressures.
The association between mother‐to‐child HIV transmission knowledge and antenatal care utilisation in Cameroon
Authors: Dhillon Satveer , Amoak Daniel , Sano Yujiro , Antabe Roger , Luginaah Isaac 
Published: August 2023

AbstractWhile the health benefits of antenatal care (ANC) utilisation for mothers and their infants have been well documented, very few studies have explored the association between mother‐to‐child transmission (MTCT) knowledge of human immunodeficiency virus (HIV) and mothers' utilisation of ANC in HIV endemic regions such as Cameroon. To address this void in the literature, we use the 2018 Cameroon Demographic and Health Survey to examine the association between mother's knowledge of MTCT of HIV and the three strands of ANC utilisation (i.e., number of ANC visits, timing to first ANC visit, and place of delivery). We found that women with adequate MTCT knowledge were more likely to have four to seven ANC visits (relative risk ratio [RRR] = 1.39, p < 0.001) and more than eight ANC visits (RRR = 1.43, p < 0.05), compared to their counterparts with inadequate knowledge. Similarly, women with adequate MTCT knowledge were more likely to attend ANC within the first trimester (odds ratio [OR] = 1.16, p < 0.05) and to give birth in a health facility (OR = 1.37, p < 0.001) than their counterparts with inadequate MTCT of HIV knowledge. These results remained robust after controlling for theoretically relevant variables. Based on these findings, we discussed several implications for policymakers and recommendations for future research.
Enhancing early parenting in the community: Preliminary results from a learning collaborative approach to scale up Attachment and Biobehavioral Catch‐up
Authors: Appleyard Carmody Karen , Murray Kathryn J. , Williams Breanna , Frost Allison , Coleman Cheri , Sullivan Kelly 
Published: August 2023

AbstractAttachment and Biobehavioral Catch‐up (ABC) is a promising home‐visiting intervention promoting sensitive caregiving and secure parent–child attachment in families with young children. The goal of this study was to examine a learning collaborative approach to disseminating ABC in a community setting. Training outcomes (e.g., trainee completion, satisfaction, effectiveness of training methods) and intervention outcomes (e.g., parent behavior, parent beliefs, child socioemotional development) were examined. Eighteen practitioners participated in the ABC learning collaborative; 13 completed training. Quantitative and qualitative measures indicated that trainees were satisfied with their experience and valued the unique collaboration opportunities offered by the learning collaborative. In addition, trainees served 67 families in the community, 37 of whom completed all sessions of ABC. The study was conducted in the United States. Racial demographics of the children in the sample included: 56.7% White, 22.4% Black/African–American, 17.9% Bi‐ or Multi‐racial, and 3.0% unknown. Regarding ethnicity, 80.6% were Non‐Hispanic/Latino, 10.4% were Hispanic/Latino, and 9.0% were unknown. Caregivers who completed ABC showed more sensitive parenting behavior and reported positive changes in their perceived self‐efficacy and their beliefs around infant crying. Children who received ABC showed increased socioemotional functioning. Results demonstrate successful dissemination of ABC in the community using a learning collaborative approach.
Exploring the connections between disciplinary and digital literacies in history
Authors: Lesley Mellinee , Stewart Elizabeth , Keene Johanna 
Published: August 2023

AbstractGiven the prevalence of digital tools and platforms as the primary pedagogical means through which to organize and deliver content in schools, this study examined how history teachers instructed students in digital literacies to develop their disciplinary knowledge through project‐based learning. Although several studies addressing new literacies tout digital mediums as a way to ignite adolescents' imagination and bring together conceptual and social learning, this research revealed students struggled with navigating numerous digital literacy tasks in the context of learning to read, write, and think like historians, which hindered their ability to curate knowledge utilizing disciplinary literacies. Thus, this study raises questions about the methods needed to converge disciplinary knowledge and digital literacies as well as the extent to which Information Communication Technologies can transform rather than replace disciplinary practices. Implications for student engagement are discussed.
TMCO3, a Putative K+:Proton Antiporter at the Golgi Apparatus, Is Important for Longitudinal Growth in Mice and Humans
Authors: Holling Tess , Brylka Laura , Scholz Tasja , Bierhals Tatjana , Herget Theresia , Meinecke Peter , Schinke Thorsten , Oheim Ralf , Kutsche Kerstin 
Published: August 2023

AbstractIsolated short stature, defined as short stature without any other abnormalities, is a common heterogeneous condition in children. Exome sequencing identified the homozygous nonsense variant c.1832G>A/p.(Trp611*) in TMCO3 in two sisters with isolated short stature. Radiological studies, biochemical measurements, assessment of the skeletal status, and three‐dimensional bone microarchitecture revealed no relevant skeletal and bone abnormalities in both sisters. The homozygous TMCO3 variant segregated with short stature in the family. TMCO3 transcript levels were reduced by ~50% in leukocyte‐derived RNA of both sisters compared with controls, likely due to nonsense‐mediated mRNA decay. In primary urinary cells of heterozygous family members, we detected significantly reduced TMCO3 protein levels. TMCO3 is functionally uncharacterized. We ectopically expressed wild‐type TMCO3 in HeLa and ATDC5 chondrogenic cells and detected TMCO3 predominantly at the Golgi apparatus, whereas the TMCO3W611* mutant did not reach the Golgi. Coordinated co‐expression of TMCO3W611*‐HA and EGFP in HeLa cells confirmed intrinsic instability and/or degradation of the mutant. Tmco3 is expressed in all relevant mouse skeletal cell types. Highest abundance of Tmco3 was found in chondrocytes of the prehypertrophic zone in mouse and minipig growth plates where it co‐localizes with a Golgi marker. Knockdown of Tmco3 in differentiated ATDC5 cells caused reduced and increased expression of Pthlh and Ihh, respectively. Measurement of long bones in Tmco3tm1b(KOMP)Wtsi knockout mice revealed significant shortening of forelimbs and hindlimbs. TMCO3 is a potential member of the monovalent cation:proton antiporter 2 (CPA2) family. By in silico tools and homology modeling, TMCO3 is predicted to have an N‐terminal secretory signal peptide, forms a dimer localized to the membrane, and is organized in a dimerization and a core domain. The core domain contains the CPA2 motif essential for K+ binding and selectivity. Collectively, our data demonstrate that loss of TMCO3 causes growth defects in both humans and mice. © 2023 American Society for Bone and Mineral Research (ASBMR).
Properly colored and rainbow C4 ${C}_{4}$'s in edge‐colored graphs
Authors: Wu Fangfang , Broersma Hajo , Zhang Shenggui , Li Binlong 
Published: August 2023

AbstractWe present new sharp sufficient conditions for the existence of properly colored and rainbow 's in edge‐colored graphs. Our first results deal with sharp color neighborhood conditions for the existence of properly colored 's in edge‐colored complete graphs and complete bipartite graphs, respectively. Next, we characterize the extremal graphs for an anti‐Ramsey number result due to Alon on the existence of rainbow 's in edge‐colored complete graphs. We also generalize Alon's result from complete to general edge‐colored graphs. Finally, we derive a structural property regarding the extremal graphs for a bipartite counterpart of Alon's result due to Axenovich, Jiang, and Kündgen on the existence of rainbow 's in edge‐colored complete bipartite graphs. We also generalize their result from complete to general bipartite edge‐colored graphs.
The average order of a connected induced subgraph of a graph and union‐intersection systems
Authors: Vince Andrew 
Published: August 2023

AbstractBecause connectivity is such a basic concept in graph theory, extremal problems concerning the average order of the connected induced subgraphs of a graph have been of notable interest. A particularly resistant open problem is whether or not, for a connected graph of order , all of whose vertices have degree at least 3, this average is at least . It is shown in this paper that if is a connected, vertex transitive graph, then the average order of the connected induced subgraphs of is at least .The extremal graph theory problems mentioned above lead to a broader theory. The concept of a Union‐Intersection System (UIS) is introduced, being a finite set of points and a set of subsets of called blocks satisfying the following simple property for all : if , then . To generalize results on the average order of a connected induced subgraph of a graph, it is conjectured that if a UIS is, in various senses, “connected and regular,” then the average size of a block is at least half the number of points. We prove that if a union‐intersection set system is regular, completely irreducible, and nonredundant, then the average size of a block is at least half the number of points.
Diagnosis and management of children with McArdle Syndrome (GSD V) in New South Wales
Authors: Adams Louisa , Selvanathan Arthavan , Batten Kiera J. , van Doorn Nancy , Thompson Susan , Mitchell Ashleigh , Sampaio Hugo , Dalkeith Troy , Russell Jacqui , Ellaway Carolyn J. , Farrar Michelle , Broderick Carolyn , Bhattacharya Kaustuv 
Published: August 2023

AbstractGlycogen storage type V (GSD V—McArdle Syndrome) is a rare neuromuscular disorder characterised by severe pain early after the onset of physical activity. A recent series indicated a diagnostic delay of 29 years; hence reports of children affected by the disorder are uncommon (Lucia et al., 2021, Neuromuscul Disord, 31, 1296–1310). This paper presents eight patients with a median onset age of 5.5 years and diagnosis of 9.5 years. Six patients had episodes of rhabdomyolysis with creatine kinase elevations >50 000 IU/L. Most episodes occurred in relation to eccentric non‐predicted activities rather than regular exercise. One of the patients performed a non‐ischaemic forearm test. One patient was diagnosed subsequent to a skeletal muscle biopsy, and all had confirmatory molecular genetic diagnosis. Three were homozygous for the common PYGM:c.148C > T (p.Arg50*) variant. All but one patient had truncating variants. All patients were managed with structured exercise testing to help them identify ‘second‐wind’, and plan an exercise regimen. In addition all also had an exercise test with 25 g maltodextrin which had statistically significant effect on ameliorating ratings of perceived exertion. GSD V is under‐recognised in paediatric practice. Genetic testing can readily diagnose the condition. Careful identification of second‐wind symptomatology during exercise with the assistance of a multi‐disciplinary team, allows children to manage activities and tolerate exercise. Maltodextrin can be used for structured exercise, but excessive utilisation may lead to weight gain. Early intervention and education may improve outcomes into adult life.