bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Classification of “Program Sembako” recipients in Payobasung West Sumatra based on the K-nearest neighbors classifier
Authors: YOZZA HAZMIRA , AZIZAH NINDI MAULA , YULIANTI LYRA , RAHMI IZZATI 
Published: June 2023

The "Sembako Program" is a program carried out by the Indonesian government to improve the welfare of low-income communities. The purposes of this study are: (a) to determine the classification of households that deserve to receive basic-food assistance in Koto Panjang Payobasung, West Sumatra, using the KNN classifier and (b) to determine the optimal number of nearest neighbors used in the classification process. The measure of proximity between objects used is the Gower dissimilarity coefficient. This research used primary data consisting of 175 households collected purposively in a survey conducted on all households in Payobasung. The optimal K value is determined by implementing a 5-fold cross-validation procedure. The result showed that the best classification process is when K = 3 nearest neighbors are used since it produces the highest accuracy coefficient and Mattews correlation coefficient (MCC). Therefore, for further work, in deciding the eligibility of a household to receive the Sembako Program in Payobasung, KNN can be used by considering its 3 nearest neighbors
The Concept and Significance of Political Awareness towards the State and Society
Authors: Nasser Zain Al-Abdeen Ahmed  , Layla Eissa Abu Al-Qasim  
Published: June 2023

Abstract: Political consciousness is an individual's awareness of their society's reality, as well as their regional and international environment. It involves understanding the different problems of the era and the influential forces involved in decision-making, both domestically and globally. It encompasses knowing the facts, monitoring influential aspects and forces, tracking events, analyzing and exploring their backgrounds, dimensions, and effects. Additionally, it entails understanding the traditions, customs, cultures, sciences, prevailing and obsolete laws that have evolved and continue to shape it. It also involves familiarizing oneself with the terminology, political, literary, and scientific languages of the era in order to read and analyze its discourse, to gain knowledge about the projects of friends and foes, and to explore the various transformative experiences and investigate the reasons behind their success or failure.
Therefore, societal political consciousness acts as a supportive bond for individuals in confronting their social reality, resolving its problems, and protecting it from regional and international challenges. It serves as a stabilizing force for society, both in its internal and external dealings. This research aims to explain the concept of political consciousness, its sources, and its importance for the state and society.
Development of Interactive E-Modules to Increase Learning Motivation and Science Literacy in Elementary School Students
Authors: Christina Ismaniati  , Baroroh Iskhamdhanah  
Published: June 2023

The article aimed to produce interactive e-modules from my country that meets the qualified criteria and to know the effectiveness of the interactive e-modules of my country produced to improve the learning motivation and science literacy of elementary school students of grade IV in the nearby. The research used research and development (R&D), with ADDIE model. The subject of a pilot project for a small group trial consists of 15 students and 1teacher in SD Negeri Soka. Next, the test subject of the field trial consists of 20 Muhammadiyah Kalinampu 1 students as a control class and 20 students IV grade SD Muhammadiyah Kalipakem 1 as an experimental class. Collecting data used interview guide, observation guidelines, product assessment sheet, teacher-response scale, student response scale, and the motivational scale of study and science literary test. The results showed that: (1) the resulting interactive e-module met the criteria of "very appropriate" according to the assessment of media experts and material experts; in the one-to-one trial, it obtained the "Decent" category from the responses given by the teacher and obtained the "Easy" category. Very Feasible" from the responses of students, while in the small group trial, the category "Very Eligible" was obtained from the responses given by the teacher and students; (2) the interactive e-module was found effectively increase learning motivation and science literacy of fourth-grade primary school students. The results of the t-test and the MANOVA test showed a significant level of 0.05, indicating the interactive e-modules, 'the richness of my country,' can significantly increase the learning motivation and science literacy of fourth-grade elementary school students with a significance value of 0.000 <0.05.
Keywords : Interactive E-module, Learning Motivation, Science Literacy
Bioequivalence study of two formulations of rivaroxaban in healthy adult subjects under fasting conditions
Authors: Pena Evelyn , Inatti Alfredo , Martín Xenón S. 
Published: June 2023

Objectives:
Oral anticoagulants exert their antithrombotic effect by disrupting the coagulation cascade. Rivaroxaban is the first oral agent to be developed that inhibits the coagulation process by binding directly to Factor Xa in a competitive manner. The aim of this study was to demonstrate the bioequivalence (BE) and safety of a generic formulation of rivaroxaban by comparing their pharmacokinetic (PK) parameters through statistical data and criteria of validation. Oral tablet formulations of 20 mg of a commercial product rivaroxaban reference (R) were tested against a generic product test (T) in 24 healthy adults under fasting condition.

Materials and Methods:
The study was an open label, balanced, randomized, two-treatment, two-period, two-sequence, single oral dose, and crossover study. Blood samples were collected pre-dose and at specified intervals up to 48-h post-dose to evaluate PK parameters by quantifying the concentration of rivaroxaban in plasma using a validated Liquid chromatography-mass spectrometry (LC-MS/MS) method of analysis. Statistics and confidence intervals (CIs) were calculated for BE purposes.

Results:
The geometric means of the T/R ratios and 90% confidence intervals (CIs) were: Cmax 87.80% (82.74 –93.12%), AUC0-t 85.96% (81.88–90.24%), and AUC0-∞ 86.13% (82.2–90.35%). All PK parameters are within BE acceptance range of 80–125% for demonstration of average bioequivalence.

Conclusions:
The study demonstrates the BE and well tolerance of both formulations of rivaroxaban in healthy subjects under fasting conditions.
The Effect of Supply Chain Digitalization on Internal Supply Chain Integration of Cement Manufacturing and Distribution Firms in Ghana
Authors: Okyere S. , Osei A. , Akuh R. , Addo L. 
Published: June 2023

Purpose: The purpose of this study is to assess the effect of supply chain (SC) digitalization on the internal supply chain integration of firms with a focus on cement manufacturing and distribution firms in Ghana.
Design/Methodology/Approach: The study adopted the cross-sectional quantitative research design from 114 key players and administrative staff of cement manufacturers and distributors in Ghana using a purposive sampling technique and the use of a questionnaire for gathering the data.
Findings: The findings revealed a positive, moderate relationship between the drivers of SC digitization and internal SC integration; a negative, moderate relationship between the challenges of SC digitization and internal SC integration; a positive, strong correlation between the extent of SC digitization and internal SC integration. All the relationships were significant. Also, the drivers and inhibitors of SC digitisation revealed both positive and negative associations with the extent of SC integration.
Research Limitation: The selected firms are not fully representing the entire population of cement manufacturing and distribution firms in Ghana, which impact on the external validity of the findings.
Practical Implications: The results will help increase the performance of cement production firms and improve its SC integration. Firms invest resources in the digitalization of its SC to further improve internal SC integration.
Originality/Value: The study examines the relationship between supply chain digitalization and internal supply chain integration. While digitalization has been widely studied in supply chain management, the specific focus on how it impacts internal supply chain integration in the context of cement manufacturing and distribution firms in Ghana is relatively novel.
Prevalencia de asma en pacientes hospitalizados por neumonía asociada a infección por SARS-CoV-2
Authors: Paz-Velarde Beatriz Alejandra , Arellano-Arteaga Kevin Javier , Bedolla-Pulido Angie , Morales-Romero Jaime , Rodríguez-Lizola Juan Manuel , Bedolla-Barajas Martín 
Published: June 2023

Antecedentes: La asociación el asma con la COVID-19 continúa siendo controversial. Objetivo: establecer la prevalencia de asma en una muestra de pacientes con neumonía asociada COVID-19; además, describir las características clínicas de los pacientes con asma en comparación con los pacientes sin asma.
Métodos: Se analizaron los datos clínicos correspondientes a120 pacientes hospitalizados por neumonía asociada a infección por SARS-CoV-2. Los pacientes con y sin asma fueron comparados en función de la gravedad de la COVID-19.
Resultados: La prevalencia de asma en los pacientes con neumonía por COVID-19 fue del 3.5% (IC 95%: 1.5% a 9.6%). Al comparar la gravedad de la COVID-19 entre los pacientes con asma con los pacientes sin asma, ésta no difirió en función de los síntomas, la comorbilidad, la duración de los síntomas, la necesidad de ventilación mecánica asistida, los biomarcadores de inflamación y la ocurrencia de muerte. Los pacientes con asma y COVID-19 mostraron un fenotipo T2 alto, con pobre función respiratoria y sin uso de tratamiento regular para el control del asma.
Conclusiones: No se observaron diferencias significativas en la frecuencia de la ventilación mecánica asistida o de la muerte entre los pacientes hospitalizados por neumonía asociada con COVID-19 con y sin historia de asma.
Palabras clave: asma; COVID-19; prevalencia; SARS-CoV-2.
Vía aérea pequeña: de la definición al tratamiento
Authors: Gochicoa-Rangel Laura , Jiménez-González Carlos Adrián , Lechuga-Trejo Irma , Benítez-Pérez Rosaura Esperanza , Thirión-Romero Ireri , Hernández-Rocha Federico Isaac , Ceballos-Zúñiga Omar , Cortés-Télles Arturo , Guerrero-Zúñiga Selene , Díaz-García Roberto , Hernández-Morales Aloisia Paloma , Aguilar-Zanela Jacqueline Lorena , Torre-Bouscoulet Luis 
Published: June 2023

La vía aérea pequeña, presente desde los orígenes de la humanidad y descrita hace apenas un siglo, se ha descubierto recientemente como el sitio anatómico donde inicia la inflamación provocada por algunas enfermedades pulmonares obstructivas: asma y enfermedad pulmonar obstructiva crónica (EPOC), per se. Se ha identificado disfunción de la vía aérea pequeña en el 91% de los pacientes asmáticos y en una gran proporción de quienes padecen EPOC. En los pacientes sin enfermedad, la vía aérea pequeña representa el 98.8% (4500 mL) del volumen pulmonar total, y solo aporta del 10 al 25% de la resistencia pulmonar total; sin embargo, en sujetos con obstrucción puede suponer el 90% de la resistencia total. A pesar de esto, sus características morfológicas y funcionales permiten que la disfunción pase inadvertida por métodos diagnósticos convencionales, por ejemplo la espirometría. Con base en lo anterior, el objetivo de este estudio fue revisar el panorama general de los métodos disponibles para evaluar la vía aérea pequeña y los posibles tratamientos asociados con esta zona silente.
Palabras clave: Vía aérea pequeña; resistencia al flujo aéreo; asma; EPOC.
Reducción del contenido de IgA1 e IgA2 en la leche materna por efecto de la pasteurización y congelación
Authors: López-Marin Beatriz , Osorno-Gutiérrez Adriana Patricia , Arredondo-Vanegas Natalia 
Published: June 2023

Objetivo: Determinar el efecto de la pasteurización y congelación en el contenido de IgA1 e IgA2 en la leche materna. Métodos: Estudio observacional y retrospectivo, llevado a cabo en mujeres que tuvieran más de 30 días de ofrecer lactancia a su neonato, y pudieran donar 50 mL de leche. Se determinó la concentración de IgA1 e IgA2 mediante turbidimetría, antes y después de someterse a pasteurización y congelación, cada 15 días durante 2 meses. La congelación fue a –20°C. Se encontró un contenido total de IgA de 1598,5 mg/dL. Resultados: Se seleccionaron 10 donantes de leche materna. La concentración inicial de IgA1 e IA2 fue de 651 y 945.7 mg/dL, respectivamente; al finalizar los tiempos de congelación disminuyó el contenido de ambas inmunoglobulinas: IgA1 del 74% e IgA2 del 86%. Después de los tratamientos, el contenido de inmunoglobulinas disminuyó de forma contundente, con diferencia significativa de p < 0.05. Conclusión: La pasteurización y la congelación afectan de manera importante el contenido de IgA1 e IgA en la leche materna; por tanto, la alimentación al seno materno sigue siendo la mejor forma de ofrecer toda protección inmunológica al lactante. Palabras claves: Leche materna; inmunoglobulinas; IgA1; IgA2; pasteurización; congelación, turbidimetría.
Vasculitis leucocitoclástica como efecto adverso del propiltiouracilo. Reporte de un caso
Authors: Cortés-Guzmán José Santiago , Veloza Karen T. , Domínguez Juan D. , Pinzón-Tovar Alejandro 
Published: June 2023

Antecedentes: La causa más frecuente de hipertiroidismo es la enfermedad de Graves. El propiltiouracilo es uno de los medicamentos más prescritos para esta enfermedad. Uno de los efectos adversos dermatológicos del propiltiouracilo es la vasculitis leucocitoclástica.
Reporte de caso: Paciente femenina de 18 años, alérgica al metamizol, con vasculitis asociada a ANCAs, con características de vasculitis leucocitoclástica provocada por el consumo de propiltiouracilo. No se observó afectación sistémica. Dos meses después de suspender el propiltiouracilo desaparecieron casi por completo las lesiones en la piel.
Conclusiones: La vasculitis leucocitoclástica debe considerarse en el espectro de complicaciones provocadas por el consumo de propiltiouracilo. Las lesiones pueden manifestarse con el paso del tiempo, desde unas semanas hasta años después de consumir el fármaco. Cuando no existe afectación sistémica, la suspensión del propiltiouracilo es suficiente para detener la enfermedad.
Palabras clave: Hipertiroidismo; enfermedad de Graves; propiltiouracilo; vasculitis asociada con anticuerpos anti-citoplasma del neutrófilo; vasculitis leucocitoclástica.
Histomorphometric effects of energy drink consumption on pancreatic tissue of albino wistar rats.
Authors: Shahnaz Bano Memon  , Sajjad Ali Almani  , Saqib Baloch  , Shahab Hanif  , Ayesha Asad  , Rida Qureshi  
Published: June 2023

Objective: To determine the histo-morphometric effects of energy drink consumption in different doses on the pancreatic tissue of Wistar Albino rats. Study Design: Experimental study. Setting: Department of Pharmacology, Isra University, Hyderabad. Period: April 2021 to September 2021. Material & Methods: Thirty healthy albino Wistar rats of body weight 200±20 were included in the study. Rats were divided equally into three groups. Group I (Control), Group II (Low dose energy drink 7.5 ml/day) and Group III (High dose energy drink 15 ml/day). The body weight of all animals was measured. Blood samples were collected for the biochemical analysis including serum glucose, serum insulin level, and oxidative markers. Histo-pathological and morphometric findings were observed. Results: A statistically significant rise in body weight in groups II and III (p<0.05). Significantly increased serum glucose and declined insulin level was seen in group II and III compared with controls (p<0.05). There was a significantly lower level of oxidative markers observed in group III than in groups I and II (p<0.05). The mean pancreatic acini and islets diameter in groups II and III has decreased signiﬁcantly compared with group I (p<0.05). The histo-pathological grading reveals that mild to moderate parenchymal changes in the pancreatic tissue of group II rats compared with group I. While moderate to severe changes were observed in group III compared with group I and II rats. Conclusion: Caffeinated energy drink consumption results in oxidative stress and degenerative changes in the potential to seriously alter the exocrine and endocrine pancreas' normal morphology consumption.
Psikologi Tokoh “Aku” dalam Novel "Hidup Ini Brengsek dan Aku Dipaksa Menikmatinya" Karya Puthut EA dan Gindring Waste
Authors: Yudhia Bayu , Suntoko Suntoko , Nurhasanah Een 
Published: June 2023

Penelitian ini dilatarbelakangi oleh urgensi peran hawa nafsu dan naluri tokoh “aku” dalam novel Hidup Ini Brengsek dan Aku Dipaksa Menikmatinya karya Puthut EA dan Gindring Waste yang sangat liar dan luas. Penelitian ini bertujuan untuk mengetahui peran id, ego dan superego tokoh “aku” yang terdapat dalam novel Hidup Ini Brengsek dan Aku Dipaksa Menikmatinya. Penelitian menggunakan pendekatan kualitatif dan metode deskriptif. Penelitian ini akan menjadikan novel Hidup Ini Brengsek dan Aku Dipaksa Menikmatinya sebagai subjek penelitian. Data penelitian ini berupa id, ego, dan superego yang terdapat dalam novel tersebut. Hasil penelitian ini menunjukan terdapat pengaruh id, ego, dan superego terhadap perilaku sehari-hari tokoh “aku” dalam novel tersebut. Kondisi psikologi tokoh “aku” sebagai tokoh utama dipengaruhi oleh kondisi sosial masyarakat sekitar. Naluri tokoh “aku” cenderung kasar dan bebas sehingga dapat memproyeksikan kepuasan nafsu yang begitu tidak terduga. Sejalan dengan bertambahnya usia, tokoh “aku” lebih bijak untuk memilih, seperti yang ditampilkan oleh ego dan superego.Kata Kunci: Novel, Tokoh “aku”, Psikologi Sastra dan Sigmund Freud.
KEARIFAN LOKAL MASYARAKAT MELAYU DALAM PERLINDUNGAN DAN PENGELOLAAN LINGKUNGAN HIDUP DI KABUPATEN KUANTAN SINGINGI
Authors: Putri Adi Tiara , Diana Ledy 
Published: June 2023

AbstrakDalam Undang-Undang Nomor 32 Tahun 2009 tentang Perlindungan dan Pengelolaan Lingkungan Hidup, bahwa asas dalam pengelolaan lingkungan hidup berlandaskan kearifan lokal. Masyarakat Melayu yang kaya akan nilai-nilai kearifan lokalnya yang dapat ditemukan di dalam petatah, petitih, syair, tunjuk ajar, norma. Begitu juga dengan nilai-nilai kearifan lokal terkait dengan perlindungan dan pengelolaan lingkungan hidup akan dapat ditemukan dalam sumber hukumnya.. Penelitian ini berkaitan dengan penerapan nilai-nilai kearifan lokal masyarakat melayu dalam perlindungan dan pengelolaan lingkungan hidup di Kabupaten Kuantan Singingi. Kata Kunci : Kearifan Lokal, Lingkungan, Melayu AbstractIn Law Number 32 Year 2009, the principle of environmental is based on local wisdom. The Malay community has the values of local wisdom that can be found in the petatah, petitih, lyric, teaching point, norm. The values of local wisdom associated with the protection and management of the environment will be found in the source of the law. This research is related to the implementation of local wisdom values of Malay community about environmental in Kuantan Singingi.Keywords : Local Wisdom, Environment, Malay
PENGISIAN JABATAN HAKIM MAHKAMAH KONSTITUSI BERDASARKAN KAJIAN TERHADAP KREDIBILITAS DAN INDEPENDENSI HAKIM
Authors: Alsyam Alsyam 
Published: June 2023

AbstractThe personal judges of the Constitutional Court are the main pillars for realizing the independence and impartiality of the Constitutional Court. The composition of the nine judges at the Constitutional Court of the Republic of Indonesia, proposed three people by each state institution namely the People's Representative Council (DPR), the President, and the Supreme Court (MA). The involvement of the three state institutions in the mechanism for filling the positions of Constitutional Justices has the potential to trigger a conflict of interest (especially in the DPR and the President) which has an impact on the credibility and independence of the appointed Constitutional Justices. The research is doctrinal research by conceptual approach and statute approach. Results study explains that the dynamics of politics in Indonesia do not mature so that the guardian of Constitutional Court judges is threatened. Therefore, to avoid this offense, it is necessary to form an ad hoc committee in the process of selecting candidate judges for the Constitutional Court as a form of implementing independence. AbstrakPersonal hakim Mahkamah Konstitusi merupakan pilar utama untuk mewujudkan independensi dan imparsialitas Mahkamah Konstitusi. Komposisi sembilan hakim pada Mahkamah Konstitusi Republik Indonesia, diajukan tiga orang oleh masing-masing lembaga negara yakni Dewan Perwakilan Rakyat (DPR), Presiden, dan Mahkamah Agung (MA). Keterlibatan ketiga lembaga negara tersebut dalam mekanisme pengisian jabatan hakim konstitusi, berpotensi akan memicu terjadi konflik kepentingan (terutama di DPR dan Presiden) yang berdampak pada kredibilitas dan independensi hakim konstitusi yang ditetapkan. Metode penelitian ini menggunakan penelitian hukum normatif (doctrinal research) dengan pendekatan analitis (conceptual approach), pendekatan undang-undang (statute approach). Hasil penelitian ini menjelaskan bahwa dinamika perpolitikan di Indonesia tidak kunjung dewasa sehingga terancamnya marwah hakim Mahkamah Konstitusi. Oleh sebab itu, menghindarkan ketersinggungan tersebut maka perlunya membentukan panitia ad hoc dalam proses pemilihan calon hakim Mahkamah Konstitusi sebagai bentuk implementasi independensi.
Comparison of Red Betel Leaf Decoction and Aloe Vera Decoction on Decreased Sugar Levels in Patients with Diabetes Mellitus at Setia Janji Health Center
Authors: Pane Herviza Wulandary , Suryantara Bima , Kristiarini Juda Julia 
Published: June 2023

<div><table cellspacing="0" cellpadding="0" align="left"><tbody><tr><td align="left" valign="top"><p><em>Diabetes Mellitus is the third most common cause of death after cancer and cardiovascular disease in people aged 30-70 years (WHO 2016). The aim of the study was to compare the effect of red betel leaf decoction and aloe vera decoction on reducing blood sugar levels in people with diabetes mellitus at the Setia Janji Health Center.</em><em> </em><em>This research is a quantitative research. In this study the researchers used the Pre-Experiment research design with a One-Group Pretest-Posttest Design with a control approach. The research was carried out in February 2023 until it was completed at the Setia Janji Health Center. With a Sample of 40 People. Bivariate analysis using Bivariate Analysis was used to see how far the influence of each independent variable on the dependent variable used the Shapiro-Wilk data normality test and the Paired T-test paired samples.The study obtained that the average difference in blood sugar levels of DM patients before and after being given red betel leaf decoction was 82.90 mg/dL with a standard deviation of 28.069 mg/dL. The average difference in blood sugar levels of DM patients before and after being given red betel leaf decoction was 45.30 mg/dL with a standard deviation of 22.614 mg/dL. The results of the Mann Whitney statistical test obtained p = 0.000, where the p value ≤ 0.05, statistically it means that there is a difference in the average decrease in blood sugar levels given red betel leaf decoction (Piper crocatum) and aloe vera decoction. in people with diabetes mellitus at the Setia Janji Health Center. There is support from midwives in providing counseling about the benefits of decoction of red betel leaves and aloe vera as an alternative to herbal medicine in helping lower blood sugar levels in people with diabetes mellitus.</em></p><p><em> </em></p></td></tr></tbody></table></div><p><strong><em>Keywords : Aloe Vera, Decrease in KGD, DM, Red Betel Leaf</em></strong></p>