bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mobile Integrated Health Interventions for Older Adults: A Systematic Review
Authors: Louras Nathan , Reading Turchioe Meghan , Shafran Topaz Leah , Demetres Michelle R , Ellison Melani , Abudu-Solo Jamie , Blutinger Erik , Munjal Kevin G , Daniels Brock , Masterson Creber Ruth M 
Published: March 2023

Abstract

Background and Objectives
Mobile integrated health (MIH) interventions have not been well described in older adult populations. The objective of this systematic review was to evaluate the characteristics and effectiveness of MIH programs on health-related outcomes among older adults.

Research Design and Methods
We searched Ovid MEDLINE, Ovid EMBASE, CINAHL, AgeLine, Social Work Abstracts, and The Cochrane Library through June 2021 for randomized controlled trials or cohort studies evaluating MIH among adults aged 65 and older in the general community. Studies were screened for eligibility against predefined inclusion/exclusion criteria. Using at least 2 independent reviewers, quality was appraised using the Downs and Black checklist and study characteristics and findings were synthesized and evaluated for potential bias.

Results
Screening of 2,160 records identified 15 studies. The mean age of participants was 67 years. The MIH interventions varied in their focus, community paramedic training, types of assessments and interventions delivered, physician oversight, use of telemedicine, and post-visit follow-up. Studies reported significant reductions in emergency call volume (5 studies) and immediate emergency department (ED) transports (3 studies). The 3 studies examining subsequent ED visits and 4 studies examining readmission rates reported mixed results. Studies reported low adverse event rates (5 studies), high patient and provider satisfaction (5 studies), and costs equivalent to or less than usual paramedic care (3 studies).

Discussion and Implications
There is wide variability in MIH provider training, program coordination, and quality-based metrics, creating heterogeneity that make definitive conclusions challenging. Nonetheless, studies suggest MIH reduces emergency call volume and ED transport rates while improving patient experience and reducing overall health care costs.
Geophysics-steered self-supervised learning for deconvolution
Authors: Chai Xintao , Yang Taihui , Gu Hanming , Tang Genyang , Cao Wenjun , Wang Yufeng 
Published: March 2023

SUMMARYDeep learning (DL) has achieved remarkable progress in geophysics. The most commonly used supervised learning (SL) framework requires massive labelled representative data to train artificial neural networks (ANNs) for good generalization. However, the labels are limited or unavailable for field seismic data applications. In addition, SL generally cannot take advantage of well-known physical laws and thus fails to generate physically consistent results. The weaknesses of standard SL are non-negligible. Therefore, we provide an open-source package for geophysics-steered self-supervised learning (SSL; taking application to seismic deconvolution as an example). With the wavelet given, we incorporate the convolution model into the loss function to measure the error between the synthetic trace generated by the ANN deconvolution result and the observed data, steering the ANN’s learning process toward yielding accurate and physically consistent results. We utilize an enhanced U-Net as the ANN. We determine a hard threshold operator to impose a sparse constraint on the ANN deconvolution result, which is challenging for current DL platforms because no layer is available. 2-D/3-D ANNs can naturally introduce spatial regularization to the ANN deconvolution results. Tests on synthetic data and 3-D field data with available well logs verify the effectiveness of the proposed approach. The approach outperforms the traditional trace-by-trace method in terms of accuracy and spatial continuity. Experiments on synthetic data validate that sparsity promotion matters for sparse recovery problems. Field data results of the proposed approach precisely identify the layer interfaces and mostly match well with the log. All codes and data are publicly available at https://doi.org/10.5281/zenodo.7233751 (Xintao Chai).
Defining the Yangtze–Cathaysia suture zone in South China using ambient noise tomography
Authors: Ma Junwei , Guo Zhen , Huang Jingqiu , Fu Yuanyuan V , Barnard Alex 
Published: March 2023

SUMMARYThe South China Craton formed after collision between the Yangtze and Cathaysia Blocks. The suture zone between these two blocks is the crux of understanding the geological evolution of South China. Due to the relative paucity of high-resolution subsurface data, the location of the suture zone in the southwestern region remains uncertain. To find the suture zone, we created a high-resolution model of the crust and upper mantle structure using 27 months of continuous waveform data acquired from 457 stations in South China. The model uses extracted phase velocity dispersion curves of Rayleigh waves at 4–40 s from ambient noise cross-correlation functions, to perform a direct inversion for an azimuthal anisotropic VSV model. In the crust a prominent belt of strong azimuthal anisotropy exists between the Yangtze and Cathaysia Blocks. The fast polarization axes in this belt correspond to the NE-trending orogen between the two blocks. In the deeper crust of the Cathaysia Block we image multiple areas of diffuse low-velocity anomalies. As defined by the margins of the strongly anisotropic belt, the Yangtze–Cathaysia suture zone is delineated by lines that traverse: Shaoxing–Jiangshan–Pingxiang–Longsheng–Hechi and Shitai–Jiujiang–Yueyang–Dayong–Jishou. Further analysis of the seismic data links deep low velocities with widespread Late Mesozoic magmatism in the Cathaysia Block. The deep low velocities are likely a result of dehydration of the subducting Pacific Plate causing mantle upwelling and underplating.
Inequitable access to sport in juvenile justice across the USA: findings from a national survey
Authors: McDonough Kalyn , Knight Erin K 
Published: March 2023

SummaryThe USA incarcerates more young people than any other industrialized nation in the world, and black youth are much more likely to be incarcerated than white youth. Young people who interface with the criminal justice system are at higher risk for poor health upon release and the justice system is believed to be a contributor to racial health disparities. Sport participation during incarceration has the potential to improve health and health equity, but the evidence on the health benefits of youth sport participation has almost exclusively focused on school and community settings in the USA with little attention to non-traditional settings, such as the justice system. Given the poor health consequences of incarceration, the potential of sport to improve health, and the lack of research on this phenomenon in the USA, our objective was to describe the landscape of sport programming in juvenile correctional facilities and provide a baseline understanding upon which future research can build. Through a cross-sectional survey of all long-term secure juvenile correctional facilities in the USA (n = 211), we found 55.1% operate a sport program. Among facilities with programs, there was a range of sport program offerings. Gender disparities in access to various types of programs exist, with girls generally having less opportunity than boys. Most facilities reported a purpose of positive youth development in the operation of their programs. These findings have important implications for health promotion and the further integration of sport and juvenile justice as part of a public health agenda.
Prioritizing well-being in K-12 education: lessons from a multiple case study of Canadian school districts
Authors: Montemurro Genevieve , Cherkowski Sabre , Sulz Lauren , Loland Darlene , Saville Elizabeth , Storey Kate E 
Published: March 2023

SummaryIncreasingly, school districts are looking for insights on how to embed a well-being focus across school communities. Well-being in K-12 education is proven to support positive mental health, improve academic performance and contribute to positive outcomes for students and staff. How districts transition to deeply integrate well-being into existing priorities and practices is not well understood. Insights on such shifts can help inform widespread change in education. In 2020, six Canadian school districts participated in case study research to examine how and why districts were able to shift their culture to one that prioritizes well-being. Fifty-five school community members participated in individual semi-structured interviews to explore their perception of well-being in their school communities. Analysis identified six themes: well-being is wholistic and requires balance, student and staff well-being are interconnected, organizational leadership sustains implementation, connection and voice as a catalyst to well-being, building capacity to support well-being action, and charting and re-charting a course. Findings increase our understanding of system-level change, and provide insights to support well-being in education.
C
0-hybrid high-order methods for biharmonic problems
Authors: Dong Zhaonan , Ern Alexandre 
Published: March 2023

Abstract
We devise and analyze $C^0$-conforming hybrid high-order (HHO) methods to approximate biharmonic problems with either clamped or simply supported boundary conditions. $C^0$-conforming HHO methods hinge on cell unknowns that are $C^0$-conforming polynomials of order $(k+2)$ approximating the solution in the mesh cells and on face unknowns, which are polynomials of order $k\ge 0$ approximating the normal derivative of the solution on the mesh skeleton. Such methods deliver $O(h^{k+1})$$H^2$-error estimates for smooth solutions. An important novelty in the error analysis is to lower the minimal regularity requirement on the exact solution. The technique to achieve this has a broader applicability than just $C^0$-conforming HHO methods, and to illustrate this point, we outline the error analysis for the well-known $C^0$-conforming interior penalty discontinuous Galerkin methods as well. The present technique does not require a $C^1$-smoother to evaluate the right-hand side in case of rough loads; loads in $W^{-1,q}$, $q&gt;\frac {2d}{d+2}$, are covered, but not in $H^{-2}$. Finally, numerical results including comparisons to various existing methods showcase the efficiency of the proposed $C^0$-conforming HHO methods.
Categories for Grassmannian Cluster Algebras of Infinite Rank
Authors: August Jenny , Cheung Man-Wai , Faber Eleonore , Gratz Sira , Schroll Sibylle 
Published: March 2023

Abstract
We construct Grassmannian categories of infinite rank, providing an infinite analogue of the Grassmannian cluster categories introduced by Jensen, King, and Su. Each Grassmannian category of infinite rank is given as the category of graded maximal Cohen–Macaulay modules over a certain hypersurface singularity. We show that generically free modules of rank $1$ in a Grassmannian category of infinite rank are in bijection with the Plücker coordinates in an appropriate Grassmannian cluster algebra of infinite rank. Moreover, this bijection is structure preserving, as it relates rigidity in the category to compatibility of Plücker coordinates. Along the way, we develop a combinatorial formula to compute the dimension of the $\textrm {Ext}^{1}$-spaces between any two generically free modules of rank $1$ in the Grassmannian category of infinite rank.
Anticancer potential of fermented milk with autochthonous lactic acid bacteria
Authors: Mahmoudi Mandana , Khomeiri Morteza , Saeidi Mohsen , Davoodi Homa , Memarian Ali 
Published: March 2023

AbstractAimsThe purpose of this study was to investigate the effect of fermented milk supernatants of autochthonous lactic acid bacteria, including Lactobacillus helveticus KMCH1 (ON561781), Lactococcus lactis KMCM3 (ON561782), and Lactiplantibacillus plantarum KMJC4 (ON615217), on human colon cancer (HT-29) and normal mouse fibroblast (L929) cells in vitro.Methods and ResultsProteolytic activity, 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide test, evaluation of apoptosis induction, and cell cycle arrest by flow cytometry were the assays performed in this study. The measurement of proteolytic activity of three types of fermented milk supernatant using an orthophthalaldehyde reagent showed that the fermented milk supernatant of L. helveticus KMCH1 included the highest proteolysis. Three types of fermented milk supernatant showed anticancer effects on HT-29 cell in a time- and concentration-based manner (at a concentration of 16 mg ml−1 for 72 h of incubation), while the effect of three types of supernatant on inhibition of L929 cell was 3%–10%. Besides, three types of supernatant inhibited HT-29 cell proliferation by inducing apoptosis and cell cycle arrest in the S phase.ConclusionsAutochthonous lactic acid bacteria strains were able to produce bioactive peptides with anticancer effects in fermented milk. Inhibition of HT-29 cell proliferation was dependent on peptide concentration.
Evaluation of oxidized beta-carotene on sow and piglet immune systems, sow reproductive performance, and piglet growth
Authors: Elefson Sarah K , Ross Jason W , Rademacher Christopher J , Greiner Laura L 
Published: March 2023

AbstractThis study aimed to determine if supplementation of oxidized-beta carotene (OxC-Beta) improved sow reproductive performance, litter growth performance, vitamin A status, and ability to alter immune cells abundance in sows and piglets, subsequent litter performance, and nursery growth performance. On approximately day 60 of gestation and through the lactation period, 194 sows (blocked by parity) were assigned to a common gestation diet or the common diet supplemented with 80 ppm oxidized beta-carotene (OxC-Beta, Aviagen, Ottawa, ON, Canada). A subset of sows (N = 54 per treatment) were sampled for blood and body weight recorded at the beginning of the study, farrowing, and weaning. A blood sample was taken from a subset of piglets at birth and weaning, and all piglet weights were recorded. Blood was analyzed for vitamin A as retinol concentrations and immunoglobulin G (IgG) and immunoglobulin M (IgG) levels were assessed from the sow’s blood. Twelve pigs (N = 6 per treatment) were euthanized at birth and weaning. The livers were collected and analyzed for the Kupffer cell phagocytic activity through flow cytometry. Whole blood was analyzed via flow cytometry for cluster of differentiation (CD335, CD8, and CD4). Colostrum during farrowing and milk at weaning were analyzed for IgG and IgA concentrations. Data were analyzed via SAS 9.4 using MIXED and frequency procedures where appropriate. No differences (P &gt; 0.05) between dietary treatments were observed in sow reproductive performance, feed intake, wean to estrus interval, or piglet growth performance. No differences (P &gt; 0.05) were observed in the plasma or liver for vitamin A. No differences (P &gt; 0.05) were observed in the composition of the colostrum or milk. No immunological differences (P &gt; 0.05) were observed in the piglets’ liver and blood or sow antibodies in colostrum and milk. The supplementation of OxC-Beta did (P &lt; 0.05) decrease IgM and tended (P &lt; 0.10) to decrease IgG in sow plasma. No differences (P &gt; 0.05) were observed in the reproductive performance of subsequent litter information from the sows. Gilt litter weaning weight and feed intake were reduced (P &lt; 0.05) compared to sow performance. In conclusion, the supplementation of OxC-Beta at 80 ppm from day 60 of gestation through lactation does not affect the reproductive performance of sows, litter growth performance, vitamin A status, piglet immune status, and antibodies or composition in colostrum and milk.
Curcumin Protects Human Dermal Fibroblasts Exposed to Hydrogen Peroxide by Regulating Autophagy Level and Reactive Oxygen Species Generation
Authors: Pan Tianyun , Zhang Shuxian , Fei Huanhuan , Hu Yun 
Published: March 2023

Abstract
Curcumin is getting more and more attention in wound healing and scar prevention because of its wide range of pharmacological effects, such as anti-inflammation, antioxidant, and anti-fibrosis. The activity of fibroblasts suffering from oxidative stress is reduced, affecting wound repair. In this study, we investigated whether curcumin treatment (10 μM, 24 hours) had protective effects on human dermal fibroblasts (HDFs) exposed to hydrogen peroxide (H2O2, 300 μM, 12 hours). We found that curcumin alleviated H2O2-induced accumulation of reactive oxygen species (ROS, the fold change relative to the untreated control was 1.75 [SD ± 0.21] vs 5.23 [SD ± 0.51], P &lt; .001) and improved the expression and activities of antioxidant enzymes superoxide dismutase 1 (66.61 U [SD ± 7.47] vs 46.39 U [SD ± 6.82]/106 cells, P &lt; .05) and catalase (9.77 U [SD ± 1.82] vs 4.61 U [SD ± 0.94]/106 cells, P &lt; .01), accompanied with increased cell proliferation and migration but decreased senescence. In addition, we found that curcumin reduced the inhibition of autophagy by H2O2, as manifested in the increased autophagic vacuoles (P &lt; .05) and higher expression of autophagy-related proteins including phosphoinositide-3-kinase class III (P &lt; .001), light chain 3 form II (P &lt; .001), and Beclin1 (P &lt; .01). However, intracellular redox status deteriorated again and curcumin’s protection effects were partially canceled after autophagy was inhibited by 3-methyladenine pretreatment. These data suggest that rescue of HDFs from oxidative damage by curcumin may related to the regulation of autophagy levels and ROS generation.
Multicentre Analysis of Cost, Uptake and Safety of Canadian Multidisciplinary Pancreatic Cyst Guidelines
Authors: Verhoeff Kevin , Webb Alexandria N , Krys Daniel , Anderson Danielle , Bigam David L , Fung Christopher I 
Published: March 2023

AbstractBackgroundPancreatic cystic lesions (PCLs) are common, with several guidelines providing surveillance recommendations. The Canadian Association of Radiologists published surveillance guidelines (CARGs) intended to provide simplified, cost-effective and safe recommendations. This study aimed to evaluate cost savings of CARGs compared to other North American guidelines including American Gastroenterology Association guidelines (AGAG) and American College of Radiology guidelines (ACRG), and to evaluate CARG safety and uptake.MethodsThis is a multicentre retrospective study evaluating adults with PCL from a single health zone. MRIs completed from September 2018–2019, one year after local CARG guideline implementation, were reviewed to identify PCLs. All imaging following 3–4 years of CARG implementation was reviewed to evaluate true costs, missed malignancy and guideline uptake. Modelling, including MRI and consultation, predicted and compared costs associated with surveillance based on CARGs, AGAGs and ACRGs.Results6698 abdominal MRIs were reviewed with 1001 (14.9%) identifying PCL. Application of CARGs over 3.1 years demonstrated a &gt;70% cost reduction compared to other guidelines. Similarly, the modelled cost of surveillance for 10-years for each guideline was $516,183, $1,908,425 and $1,924,607 for CARGs, AGAGs and ACRGs respectively. Of patients suggested to not require further surveillance per CARGs, approximately 1% develop malignancy with fewer being candidates for surgical resection. Overall, 44.8% of initial PCL reports provided CARG recommendations while 54.3% of PCLs were followed as per CARGs.ConclusionsCARGs are safe and offer substantial cost and opportunity savings for PCL surveillance. These findings support Canada-wide implementation with close monitoring of consultation requirements and missed diagnoses.
Translation-invariant functional clustering on COVID-19 deaths adjusted on population risk factors
Authors: Cheam Amay , Fredette Marc , Marbac Matthieu , Navarro Fabien 
Published: March 2023

Abstract
This paper focuses on clustering the COVID-19 death rates reported in Europe and the United States. Several methods have been developed to cluster such functional data. However, these methods are not translation-invariant (TI) and thus cannot handle different times of arrivals of the disease, nor can they consider external covariates and so are unable to adjust for the population risk factors of each region. We propose a novel three steps clustering method to circumvent these issues. First, feature extraction is performed by TI wavelet decomposition, which permits to deal with the different onsets. Then, single-index regression is used to neutralize disparities caused by population risk factors. Finally, a nonparametric mixture is fitted on the regression residuals to achieve the region clustering.
An Assessment of Gender Equity and Parity Among “Nontraditional” Pathology Awards
Authors: Jacobs Jeremy W , Adkins Brian D , Allen Elizabeth S , Parra-Herran Carlos , Stephens Laura D , Woo Jennifer S , Booth Garrett S 
Published: March 2023

Abstract

Objective
The aim of this study was to assess the gender composition of nontraditional pathology recognition award recipients.

Methods
Cross-sectional analysis of American Society for Clinical Pathology (ASCP) Top Five 40 Under Forty and The Pathologist Power List award recipients’ gender. Gender was independently analyzed by 2 authors using pronouns. Two analyses were performed: difference in gender parity and difference in gender equity for award recipients.

Results
From 2014 through 2022, 618 total awards were conferred. Significantly more men than women received an award overall (57.1% vs 42.9%; P &lt; .001). Compared with population benchmarks, awards conferred to US-based nontrainee pathology physicians (men 56.2%, women 43.8%; P = .091) and US-based pathology physician trainees (men 60.5%, women 39.5%; P = .15) are equitable. Conversely, gender inequities exist among awards conferred to US-based nonphysician laboratory professionals (men 51.7%, women 48.3%; P &lt; .001).

Conclusion
The Pathologist Power List and Top Five ASCP 40 Under Forty awards have not completely achieved gender parity, and gender inequities remain among subgroups.
Repeating periodic eruptions of the supernova impostor SN 2000ch
Authors: Aghakhanloo Mojgan , Smith Nathan , Milne Peter , Andrews Jennifer E , Filippenko Alexei V , Jencson Jacob E , Sand David J , Van Dyk Schuyler D , Wyatt Samuel , Zheng WeiKang 
Published: March 2023

ABSTRACT
We analyse photometric observations of the supernova (SN) impostor SN 2000ch in NGC 3432 covering the time since its discovery. This source was previously observed to have four outbursts in 2000–2010. Observations now reveal at least three additional outbursts in 2004–2007, and 16 outbursts in 2010–2022. Outburst light curves are irregular and multipeaked, exhibiting a wide variety of peak magnitude, duration, and shape. The outbursts after 2008 repeat with a period of 200.7 ± 2 d, while the outburst in 2000 seems to match with a shorter period. The next outburst should occur around January/February 2023. We propose that these periodic eruptions arise from violent interaction around times of periastron in an eccentric binary system, similar to the periastron encounters of η Carinae leading up to its Great Eruption, and resembling the erratic pre-SN eruptions of SN 2009ip. We attribute the irregularity of the eruptions to the interplay between the orbit and the variability of the luminous blue variable (LBV) primary star, wherein each successive periastron pass may have a different intensity or duration due to the changing radius and mass-loss rate of the LBV-like primary. Such outbursts may occasionally be weak or undetectable if the LBV is relatively quiescent at periastron but can be much more extreme when the LBV is active. The observed change in orbital period may be a consequence of mass lost in outbursts. Given the similarity to the progenitor of SN 2009ip, SN 2000ch deserves continued attention in the event it is headed for a stellar merger or an SN-like explosion.