bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prospects for Utilizing Codiaeum variegatum L. Leaf Extract to Inhibit Propionibacterium acnes and Bacillus subtilis Growth
Authors: Hastuti U S , Sulisetijono S , Zahida N S , Labibah S B , Abdini A , Sulistiyowati N , Arlan L , Yanti V R , Puspitasari D R 
Published: January 2025

Abstract

Codiaeum variegatum L plant is medicinal plant, this plant can produce antibacterial secondary metabolites, namely: alkaloids, flavonoids, tannins, and steroids. The research is done to: examine the antibacteria effect of C. variegatum leaves ethanol extract with various concentrations against the growth inhibition of P. acnes; examine the antibacteria effect of C. variegatum leaves ethanol extract with various concentrations against the growth inhibition of B. subtilis; determine the most effective concentration of C. variegatum leaves ethanol extract to inhibit P. acnes growth; and determine the most effective concentration of C. variegatum leaves ethanol extract to inhibit B. subtilis growth. Extraction using maceration method. The antibacteria effect determination of C. variegatum leaf extract used the agar well diffusion method, each well was filled with bacteria liquid culture and incubated at 37 °C for 1 × 24 hours. The research results are there is antibacteria effect of ethanol extract C. variegatum leaves to inhibit P. acnes and B. subtilis growth; the most effective concentration of C. variegatum ethanol extract leaves to inhibit the growth of P. acnes is 90%, while the most effective concentration in inhibit B. subtilis is 100%.
Phytochemical Profile, Antioxidant and Anti-Methanogen Potential of Red Betel (Piper crocatum Ruiz and Pav) Leaf Extracts By Different Solvents
Authors: Setiasih S. , Anggraeny Y. N. , Antonius  , Puspito S. , Istiqomah N. , Bakrie B. , Indriatie R. , Rachmawati D. , Wardi W. , Latifah E. 
Published: January 2025

Abstract
The red betel leaf (Piper crocatum) from the island of Sulawesi which is used as a medicinal plant. The red betel leaf contains secondary metabolite compounds that function as bioactive substances. This research aims to determine the phytochemical content and potential antioxidant and anti-methanogen activity of red betel leaf extracts. This research was conducted at the herbal laboratory of Materia Medika, Batu City, East Java. The raw material used was red betel leaf obtained from Materia Medika Garden. The extraction of red betel leaves used 3 types of solvents with different polarities, namely n-hexane, ethyl acetate and 70% ethanol. The content of red betel leaf extracts with different solvents showed total phenols 6.5-16.43 mg/g, total tannins 1,05-4,31 mg/g, total flavonoids 8.11-18.3 mg/g. The antioxidant activity of ethyl acetate red betel leaf extract was IC50 167.1. Anti-methanogen contained in red betel leaf extracts can reduce the number of methanogens with inhibitory power 13. 34% - 55.02%. The conclusion of this study is that red betel leaf extract has the potential to be used as a feed additive and reduce methane gas emissions in ruminants.
Application of Eco-Interior Design Concept in Kollektiv Hotel Bandung
Authors: Roboy E O , Mulyadi  
Published: January 2025

Abstract
Currently, the port authorities intentionally neglect more than seventeen million shipping containers worldwide, as it is not economically viable to return them to their original locations. Given the current circumstances, we have the opportunity to transform used containers into shipping container buildings, thereby incorporating eco-friendly and sustainable practices into our modern era. Several studies have been conducted on used containers, with a focus on architectural objects, thermal comfort, and life cycle assessment. The research aims to enrich and develop knowledge about sustainable design, particularly in the concept of eco-interior design, especially in hospitality facilities. This research uses purposive sampling, with the sample being Kollektiv Hotel’s in Bandung. We employed a descriptive qualitative methodology and conducted data analysis based on Kusumarini’s eco-interior concepts. The eco-interior design attributes applied include space organisation, material selection, lighting systems, ventilation systems, water sanitation, indoor pollution, electromagnetic emissions, and waste management within the space. This research confirms the importance of eco-interior application for container buildings and is expected to serve as a reference for evaluating the application of the eco-interior concept in the hospitality industry.
Utilization of Glass-Beads for Interior Surface Material with an Experience Approach
Authors: Mulyono A , Nadim  
Published: January 2025

Abstract
Glass is one of the building materials that will be a problem to the environment when disposed of after use because It cannot be decomposed like organic waste. However, glass waste can be recycled or reused as a component of new products. This research aims to determine how people respond to glass waste in bead form when mixed as an interior surface material component. Experiments combine several types of glass beads embedded in polyester resin. Participants who are concise of designers and users are invited to give their opinions about the materials. The research employs the Material-Driven Design (MDD) method, a design approach that focuses on the unique properties of materials to guide the design process. The results of processed glass waste in several samples were explored to identify the sensory, interpretative, and affective responses. The test results found that there are tendencies to have the sensory response as a strong material. Emotionally, the material applied glass beads with violet color surrounding drew strong attention that stimulated feelings of fascination and curiosity. The created samples are recommended for commercial and modern facilities such as cafes or restaurants.
Digitally Enhanced Architecture for Sustainable Placemaking: A Systematic Review
Authors: Lovendianto J , Samodra FX T B , Ekasiwi S N N , Kim D Y 
Published: January 2025

Abstract
Digital placemaking embeds digital technology to enhance form, activity, and meaning. The inclusion of digital material into conventional placemaking diagrams indicates gaps and leads to the development of new propositions. This study aims to develop new propositions, principles, and criteria for digitally enhanced architecture for sustainable placemaking. The novelty lies in the new proposition of digitally enhanced architecture by using digital information as a formal material for sustainable placemaking through multisensory experience and two-way user-form interaction. This study uses a systematic literature review method to analyse 38 theoretical and 20 case studies based on constituent aspects (form, activity, meaning) in digital placemaking and media architecture theory to formulate design principles and criteria. The developed propositions are digital information technology as form, reciprocal multisensory interactions as activities, and perception for place meaning. The principle is digital form stimulates users’ sensors to respond via two-way interactions, constructing a perception of place meaning. The criteria are building architectural forms from digital information as a physical setting and stimulating two-way multisensory interactions for spatial perceptions and experiences associated with memory and meaning. These findings apply to places with inaccessible physical forms, so digital information can replace and stimulate interactive activities to construct, strengthen, or restore place meaning.
Building Performance Based on Seismic Conceptual Design in Temporary Housing Semeru Eruption 2021
Authors: Bahar M A 
Published: January 2025

Abstract
Indonesia’s geographical location, which often experiences earthquakes, is important in disaster mitigation programs, especially for earthquake-resistant building planning. This study uses quantitative and case study methods to determine the seismic performance in the design of temporary housing for the 2021 Mount Semeru eruption based on the Seismic Conceptual Design of Buildings. The analysis used a scoring method to measure the similarity of the case study object to seismic theory. The damage caused by the eruption, relocation of settlements, and construction of new houses are very necessary. The 2000 temporary housing units were designed using fast materials, such as light steel and gypsum board, which is not suitable for the main structure of the building. However, with a building area of only 28.8 m2, the building span is shorter, and only one floor with room partitions inside makes the structure more solid. Each building is also given a distance from another building so that vibration waves that hit the building do not spread to other buildings. From the analysis results, the design of this temporary housing has a similarity of 65.9% with the seismic theory. This design has a fairly good building performance in terms of security and safety to reduce the risk of earthquake damage. However, more detailed drawings are needed, such as structural connection systems, technical specifications, and construction guidelines, and there must also be calculations of structural strength by experts.
Design parameters for enhancing passive ventilation using vertical void in hot humid climate with high density
Authors: Hakim M N , Ekasiwi S N N , Samodra FX T B 
Published: January 2025

Abstract
Natural ventilation is deemed as one of the most suitable cooling strategy especially for hot humid climate. Natural ventilation relies on outdoor condition and requires space to provide air flow. Providing space for air flow is in hot humid climate with high density, vertical void is regarded as one of the best design for enhancing passive ventilation performance. This review synthesizes the design parameters of vertical void in hot humid climate as a method to enhance passive ventilation performance. The study uses bibliometric analysis and systematic review to analyze research trend and synthesize the design parameters from selected relevant publications. The results shows that vertical void designs are highly effective in improving passive ventilation in multi-story residential buildings. Various design variables such as aspect ratio, building height, and building to void ratio are paramount in improving ventilation performance. Strategically designed openings can maximize airflow by leveraging windward and leeward ventilation dynamics. Smaller void aspect ratio enhances ventilation efficiency across various void types, while taller chimneys increase air circulation through the stack effect. An optimal building to void ratio also improves air change rates and wind velocity, but excessively large voids may reduce airflow efficiency due to volume related dissipation.
Facile Synthesis of Carbon Dots from Chicken Feathers via Catalytic Hydrothermal Method for Photodegradation of Methylene Blue
Authors: Hastuti E. , Hikmah U. , Nuryadin B. W , Hisam U. H. 
Published: January 2025

Abstract
Chicken feathers have a high keratin content and have the potential to be used to create novel materials, such as Carbon dots (C-dots). C-dots are zero-dimensional carbon materials that can cause fluorescence, making them useful as photocatalysts. A hydrothermal technique using hydrochloric acid as catalysis with various concentrations (2, 4, and 6 M) was designed to synthesize C-dots from chicken feathers to generate a crystalline carbon core. The C-dots show that the functional groups C-O, C=C, and O-H are present in the FTIR data, and the functional group C-H increases with acid content. UV-Vis results reveal an absorbance peak at 270 and 380 nm, indicating the presence of a C-dot core. The photoluminescence measurement results, which show a cyan luminescence emission intensity peak at 430 and 460 nm, strengthen the indication of C-dots formation. According to the photodegradation results, the C-dots sample reduced the methylene blue content at the CD-2 sample by up to 80%. The synthesized C-dots derived from chicken feathers are efficient and eco-friendly materials with the potential for wastewater treatment and environmental sustainability.
Boosting non-oxide interfacial Co/SiO2 hybrid bonding by selective surface activation
Authors: Qi Xiaoyun , Zhou Shicheng , Ma Yan , Suga Tadatomo , Wang Chenxi 
Published: January 2025

Abstract
Due to its superior nanoscale properties, cobalt (Co) is highly desirable for ultrahigh-density 3D integration into materials through metal/dielectric hybrid bonding. However, this process is very challenging through Co/SiO2 hybrid bonding, as very hydrophilic SiO2 surfaces are needed for bonding during dehydration reactions and oxidation of the Co surfaces must be avoided. Additionally, the substantial coefficient of thermal expansion mismatch between the robust capping layers (Co and SiO2 layers) necessitates hybrid bonding with minimal thermal input and compression. In this study, we introduce a ternary plasma activation strategy employing an Ar/NH3/H2O gas mixture to facilitate Co/SiO2 hybrid bonding at temperatures as low as ∼200 °C, which is markedly lower than the melting point of Co (∼1500 °C). Intriguingly, non-oxide metallization at the Co–Co interface can be realized without the hindrance of a bonding barrier, thereby reducing the electrical resistance by over 40% and compression force requirements. Moreover, the enhancement in the SiO2 surface energy through active group terminations fosters extensive interfacial hydration and strengthens the mechanical properties. This research paves the way for fine-tuning bonding surfaces using a material-selective strategy, which should advance metal/dielectric hybrid bonding for future integration applications.
Interpretive Labor
Authors: Carithers Kirsten 
Published: January 2025

Abstract
Interpretive Labor: Experimental Music at Work introduces and develops the author’s theory of Interpretive Labor, based on examples from the postwar Euro-American avant-garde and other forms of experimentalism. The book establishes several models of musical work: the Executive calling the shots, the Scientist testing and refining, the Administrator making sure events happen, the Hacker subverting a given system, and the Gamer making a new system entirely. Each model of Interpretive Labor, and its representative case studies, demonstrates a unique but interrelated form of engagement with the work of being a contemporary musician. The book also explores the myriad connections between music and labor in the neoliberal present. Its characters comprise a powerful system of working methods that can help us understand creative work more broadly.
The “Administrator” Model
Authors: Carithers Kirsten 
Published: January 2025

Abstract
“The Administrator Model: ‘Women’s Work’ and New-Music Coordinators” presents the third of the author’s five models of the theory of Interpretive Labor. It considers two important figures in the history of musical experimentalism who happen to have been arts administrators: Charlotte Moorman and Renée Levine Packer. Their work enabled their perhaps better-known contemporaries—composers and performers—to create and share their music at the Avant-Garde Festivals of New York and in the Center of the Creative and Performing Arts. Administrative labor was, in the postwar era, especially gendered. This chapter addresses the gender pay gap, recent trends in labor fields traditionally considered feminine, and the issue of entrepreneurship today.
cyclicpeptide: a Python package for cyclic peptide drug design
Authors: Yang Liu , Cao Suqi , Liu Lei , Zhu Ruixin , Wu Dingfeng 
Published: January 2025

Abstract
The unique cyclic structure of cyclic peptides grants them remarkable stability and bioactivity, making them powerful candidates for treating various diseases. However, the lack of standardized tools for cyclic peptide data has hindered their potential in today’s artificial intelligence–driven efficient drug design landscape. To bridge this gap, here we introduce a Python package named cyclicpeptide specifically for cyclic peptide drug design. This package provides standardized tools such as Structure2Sequence, Sequence2Structure, and format transformation to process, convert, and standardize cyclic peptide structure and sequence data. Additionally, it includes GraphAlignment for cyclic peptide–specific alignment and search and PropertyAnalysis to enhance the understanding of their drug-like properties and potential applications. This comprehensive suite of tools aims to streamline the integration of cyclic peptides into modern drug discovery pipelines, accelerating the development of cyclic peptide–based therapeutics.
Bayesian thresholded modeling for integrating brain node and network predictors
Authors: Sun Zhe , Xu Wanwan , Li Tianxi , Kang Jian , Alanis-Lobato Gregorio , Zhao Yize 
Published: January 2025

Summary
Progress in neuroscience has provided unprecedented opportunities to advance our understanding of brain alterations and their correspondence to phenotypic profiles. With data collected from various imaging techniques, studies have integrated different types of information ranging from brain structure, function, or metabolism. More recently, an emerging way to categorize imaging traits is through a metric hierarchy, including localized node-level measurements and interactive network-level metrics. However, limited research has been conducted to integrate these different hierarchies and achieve a better understanding of the neurobiological mechanisms and communications. In this work, we address this literature gap by proposing a Bayesian regression model under both vector-variate and matrix-variate predictors. To characterize the interplay between different predicting components, we propose a set of biologically plausible prior models centered on an innovative joint thresholded prior. This captures the coupling and grouping effect of signal patterns, as well as their spatial contiguity across brain anatomy. By developing a posterior inference, we can identify and quantify the uncertainty of signaling node- and network-level neuromarkers, as well as their predictive mechanism for phenotypic outcomes. Through extensive simulations, we demonstrate that our proposed method outperforms the alternative approaches substantially in both out-of-sample prediction and feature selection. By implementing the model to study children’s general mental abilities, we establish a powerful predictive mechanism based on the identified task contrast traits and resting-state sub-networks.
Conceptualizing the Nepalese ‘Gang’
Authors: Atkinson-Sheppard S , Subedi G , Jha V , Ghimire N C 
Published: January 2025

Abstract
This article discusses the ‘gang’ in Nepal. Drawing on a two-year case study conducted in Kathmandu, involving a survey and interviews with criminal justice practitioners, government officials, NGO workers, social activists as well as interviews and focus groups with ex-street children, the article argues that gangs in Nepal are a complex social phenomenon. The term ‘gang’ is used to describe a multitude of criminal groups, many of which operate in alliance with the state. Gangs are also closely associated with organized crime and in many instances, street children become involved in these criminal groups. The article illustrates how street children develop their own groups to assist their survival. For these young people gangs provide solidarity, support, friendship and are vehicles for income generation. Thus, there is no one ‘gang’, rather many gangs, who change and evolve, the implications of which are discussed.
Prognostic value of left atrioventricular coupling index in heart failure
Authors: Kasa Gizem , Teis Albert , De Raffele Martina , Cediel German , Juncà Gladys , Lupón Josep , Santiago-Vacas Evelyn , Codina Pau , Bayés-Genis Antoni , Delgado Victoria 
Published: January 2025

Abstract

Aims
To investigate the distribution of left atrioventricular coupling index (LACI) among patients with heart failure and left ventricular ejection fraction (LVEF) &lt; 50% and to explore its association with the combined endpoint of all-cause death or HF hospitalization at long-term follow-up.

Methods and results
Patients with HF and LVEF &lt; 50% undergoing cardiac magnetic resonance were evaluated. Patients with atrial fibrillation or flutter were excluded. Left atrioventricular coupling index was measured as the ratio between the left atrial (LA) and the LV end-diastolic volumes. Patient population was divided according to LACI tertiles and followed up. Total of 478 patients (mean age 62 ± 12 years, 78% male) were included. The median value of LACI was 27.1% (interquartile range 19.9–34.5). Patients within the worst LACI tertile (≥30.9%) showed smaller LV volumes and larger LA volumes as compared with patients in the first or second tertile (LACI 6.2–22.2 and LACI 22.3–30.9, respectively). Left atrioventricular coupling index was significantly associated with the combined endpoint [hazard ratio (HR) 1.87, P = 0.01]. After adjusting for sex, age, ischaemic HF aetiology, LVEF, LA reservoir strain, diabetes mellitus, LV scar, mitral regurgitation, and LVEDVi, LACI remained significantly associated with the combined endpoint (HR 1.77, P = 0.02). Patients with the highest LACI values had worse outcomes compared with patients in first and second tertiles (HR 1.69, P = 0.02 and HR 1.77, P = 0.02, respectively).

Conclusion
In patients with HF and LVEF &lt;50%, LACI is independently associated with adverse events. Patients with most impaired left atrioventricular coupling have the worst clinical outcomes.
The Effects of Italy’s Unification on Its Dual Development: A Synthetic Control Approach
Authors: Barone Guglielmo , Chilosi David , Ciccarelli Carlo , de Blasio Guido 
Published: January 2025

Abstract
There is a long-standing debate on the effect of Italian unification (1861) on the country’s dual development. We estimate the causal impact of unification on agricultural share, literacy and railway density for the South and the Centre-North by analyzing a newly assembled panel of countries/regions with the synthetic control method. Our findings suggest that over the 50 years following the birth of the unified state, neither area drew generalized benefits from unification. Consolidation delayed industrialization in both macro areas. However, the South benefited from a strong spread of rail infrastructure, while the Centre-North enjoyed a pronounced increase in literacy.