bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integrating Tetrathiafulvalene and Nickel‐Bis(dithiolene) Units into Donor‐Acceptor Covalent Organic Frameworks for Stable and Efficient Photothermal Conversion
Authors: Li Yu‐Yang , Wei Tianqi , Liu Cheng , Zhang Zedong , Wu Lei‐Feng , Ding Mengning , Yuan Shuai , Zhu Jia , Zuo Jing‐Lin 
Published: April 2023

AbstractTetrathiafulvalene (TTF) and Ni‐bis(dithiolene) are typical conductive units widely studied in electronics, optics, and photochemistry. However, their applications in near‐infrared (NIR) photothermal conversion are often limited by insufficient NIR absorption and low chemical/thermal stability. Herein, we integrate TTF and Ni‐bis(dithiolene) into a covalent organic framework (COF) with stable and efficient NIR and solar photothermal conversion performance. Two isostructural COFs, namely Ni‐TTF and TTF‐TTF, are successfully isolated which are composed of TTF and Ni‐bis(dithiolene) units as donor‐acceptor (D−A) pairs or TTF units only. Both COFs show high BET surface areas and good chemical/thermal stability. Notably, compared with TTF‐TTF, the periodic D−A arrangement in Ni‐TTF significantly lowers the bandgap, leading to unprecedented NIR and solar photothermal conversion performance.
Impact of bortezomib‐based versus lenalidomide maintenance therapy on outcomes of patients with high‐risk multiple myeloma
Authors: Bumma Naresh , Dhakal Binod , Fraser Raphael , Estrada‐Merly Noel , Anderson Kenneth , Freytes César O. , Hildebrandt Gerhard C. , Holmberg Leona , Krem Maxwell M. , Lee Cindy , Lekakis Lazaros , Lazarus Hillard M. , Mian Hira , Murthy Hemant S. , Nathan Sunita , Nishihori Taiga , Parrondo Ricardo , Patel Sagar S. , Solh Melhem , Strouse Christopher , Vesole David H. , Kumar Shaji , Qazilbash Muzaffar H. , Shah Nina , D’Souza Anita , Sidana Surbhi 
Published: April 2023

AbstractBackgroundLenalidomide maintenance after autologous stem cell transplant (ASCT) in multiple myeloma (MM) results in superior progression‐free survival and overall survival. However, patients with high‐risk multiple myeloma (HRMM) do not derive the same survival benefit from lenalidomide maintenance compared with standard‐risk patients. The authors sought to determine the outcomes of bortezomib‐based maintenance compared with lenalidomide maintenance in patients with HRMM undergoing ASCT.MethodsIn total, the authors identified 503 patients with HRMM who were undergoing ASCT within 12 months of diagnosis from January 2013 to December 2018 after receiving triplet novel‐agent induction in the Center for International Blood and Marrow Transplant Research database. HRMM was defined as deletion 17p, t(14;16), t(4;14), t(14;20), or chromosome 1q gain.ResultsThree hundred fifty‐seven patients (67%) received lenalidomide alone, and 146 (33%) received bortezomib‐based maintenance (with bortezomib alone in 58%). Patients in the bortezomib‐based maintenance group were more likely to harbor two or more high‐risk abnormalities and International Staging System stage III disease (30% vs. 22%; p = .01) compared with the lenalidomide group (24% vs. 15%; p < .01). Patients who were receiving lenalidomide maintenance had superior progression‐free survival at 2 years compared with those who were receiving either bortezomib monotherapy or combination therapy (75% vs. 63%; p = .009). Overall survival at 2 years was also superior in the lenalidomide group (93% vs. 84%; p = .001).ConclusionsNo superior outcomes were observed in patients with HRMM who received bortezomib monotherapy or (to a lesser extent) in those who received bortezomib in combination as maintenance compared with lenalidomide alone. Until prospective data from randomized clinical trials are available, post‐transplant therapy should be tailored to each patient with consideration for treating patients in clinical trials that target novel therapeutic strategies for HRMM, and lenalidomide should remain a cornerstone of treatment.
Screening Multi‐layered Two‐dimensional Cd‐chalcogenide Structures as Potential Candidates for Photocatalysis
Authors: Zhang Daoqing , Kumar Sourabh , Xiao Shifa 
Published: April 2023

AbstractIn recent years, clean and sustainable energy generation by photocatalytic water splitting has gained enormous attention from researchers. Two‐dimensional Cd‐based structures play a central role in the research of semiconductor‐based photocatalysis. Here, a few layers of cadmium monochalcogenides (CdX; X=S, Se, and Te) are theoretically investigated using density functional theory (DFT). For their potential applicability in photocatalysis, it is proposed that they are exfoliated from the wurtzite structure with an electronic gap that depends on the thickness of the proposed systems. Our calculations address a long‐standing doubt about the stabilities of free‐standing CdX monolayers (ML). Induced buckling removes the acoustic instabilities in 2D planar hexagonal CdX structures (due to interlayer interactions) that depend on the number of neighboring atomic layers present. All studied (and stable) systems have an electronic gap of >1.68 eV, calculated with hybrid functionals (HSE06). A band‐edge alignment plot about the water‘s oxidation‐reduction potential is constructed, and a potential energy surface is constructed for the hydrogen evolution reaction. Our calculations suggest that the chalcogenide site is most favorable for hydrogen adsorption, and the energy barrier falls within the experimentally achievable limits.
Comparison of endoscopic ultrasound‐guided fine needle aspiration cytology versus endoscopic biopsy for the diagnosis of subepithelial lesions of the upper and lower gastrointestinal tract: A 10‐year retrospective single institution analysis
Authors: Collins Katrina , Yocum Bianca Puello , Mesa Hector , Cramer Harvey , Saeed Omer 
Published: April 2023

AbstractBackgroundThe aim of this study is to compare the diagnostic accuracy of endoscopic ultrasound‐guided fine needle aspiration (EUS‐FNA) versus endoscopic biopsy for the diagnosis of gastrointestinal (GI) subepithelial lesions (SELs) using surgical resection as the gold standard.MethodsAll patients who underwent EUS‐FNA of upper and lower GI SELs over a 10‐year period (2010 through 2019) were retrospectively reviewed. The medical records of all patients were reviewed and data extracted from the endoscopy, pathology, and surgical reports were analyzed.ResultsIn total, 283 patients with ages ranging from 21 to 92 years underwent EUS‐FNA for evaluation of GI SELs, 117 (41%) patients underwent endoscopic biopsy and 82 (29%) patients had concurrent surgical resection specimen. EUS‐FNA was obtained from the stomach in 167 (59%) patients, duodenum in 51 (18%) patients, esophagus in 38 (13%) patients, and colorectum in 27 (10%) patients. It was found that the largest percentage of lesions originated in the muscularis propria (36%), followed by the submucosa (26%), deep mucosa (13%), and not specified in 21%. The concordance between EUS‐FNA and endoscopic biopsy was good (correlation coefficient of 0.631, p < .001). EUS‐FNA versus endoscopic biopsy in resected cases showed sensitivity and specificity of 78% versus 68% and 84% versus 100%, respectively. The EUS‐FNA has an accuracy of 80% compared to 74% in biopsy. The diagnostic yield of EUS‐FNA and endoscopic biopsy was 64% versus 55%.ConclusionEUS‐FNA is more sensitive and more accurate than endoscopic biopsy for diagnosing GI SELs with a good concordance between the two techniques.
Development of feedback system by customized UI to improve UX of web page
Authors: Motobu Tatsuhiro , Kida Koji 
Published: April 2023

AbstractIn recent years, the number of websites has been increasing, and with it, the number of similar services. As a result, UX is becoming more and more important to measure the differentiation of a website from its competitors, and UI plays a major role in improving UX. Website developers implement a development process called HCD to improve UI. However, in HCD, there is a gap between the perception of the evaluator and the developer, resulting in a lot of man‐hours. In this paper, we propose a method for evaluating web pages using GUI operations to solve this problem. We let the evaluator of the web page edit the web page by mouse operation from the browser, and feedback the result directly to the developer. As a result of the experiment, we were able to discover problems with the web pages that could not be obtained by the conventional questionnaire. It also made it easier to design improvement plans, leading to a reduction in man‐hours.
Characterization of landslide displacements in an active fault zone in Northwest China
Authors: Shi Xuguo , Hu Xie 
Published: April 2023

AbstractLandslides can be caused by natural forcing and anthropogenic activities. Zhouqu County (China) on the eastern margin of Qinghai‐Tibet Plateau is set within the active Pingding‐Huama fault zone with evident fractures on the land surface. Frequent landslides and debris flows have occurred in this region due to river erosion, rainfall and deforestation. Here we quantified the slope movements using time‐series synthetic aperture radar interferometry (InSAR) based on the ascending and descending Sentinel‐1 satellite images acquired between October 2014 and August 2020. We observed distinct displacements in the highly fractured fault zone. The eastward and vertical displacement time series between February 2017 and July 2020 were constrained by the common‐day ascending and descending acquisitions. The eastward rates (461 mm/year) were greater than those in the vertical direction (−185 mm/year). We also note displacement discontinuities across the thrust faults beneath the Suoertou and Zhongpai landslides. Seasonal variations in the displacement time series suggest that the cyclic rainfall is the primary driver for the mass wasting processes rather than the tectonic loading. As a complement to in situ observations, our results demonstrate that InSAR is an effective tool to characterize the spatio‐temporal nature of landslide displacements in complicated geological environments.Plain Language SummaryZhouqu County in the Pingding‐Huama fault zone in the eastern margin of Qinghai‐Tibet Plateau is identified as a high priority site to research on clusters of landslides and debris flows in a mixed geodynamic setting of active tectonics, seasonal rainfall, river erosion and anthropogenic activities. However, our knowledge about landslide kinematics in this complicated region is still limited. We relied on remote sensing images from one ascending and one descending Sentinel‐1 satellite tracks to constrain the spatial–temporal displacement dynamics of active landslides from 2014 to 2020. The spatial patterns of displacements are determined by thrust faulting, river erosion, and anthropogenic activities. The temporal variations of landslide speed are mainly controlled by the seasonal rainfall rather than the tectonic loading.
Controllable Doping of Mn into Ni0.075‐xMnxAl0.025(OH)2(CO3)0.0125·yH2O for Efficient Adsorption of Fluoride Ions
Authors: Wagassa Ararso N. , Tufa Lemma T. , Lee Jaebeom , Zereffa Enyew A. , Shifa Tofik A. 
Published: April 2023

AbstractHere, the structural, optical, and adsorptive behaviors of Ni0.075‐xMnxAl0.025(OH)2(CO3)0.0125·yH2O (Ni‐Mn/Al) layered double hydroxides (LDHs) are investigated to capture fluoride from aqueous media. The 2D mesoporous plate‐like Ni‐Mn/Al LDHs are successfully prepared via a co‐precipitation method. The molar ratio of divalent to trivalent cations is maintained at 3:1 and the pH at 10. The X‐ray diffraction (XRD) results confirm that the samples consist of pure LDH phases with a basal spacing of 7.66 to 7.72 Å, corresponding to the (003) planes at 2θ of 11.47o and the average crystallite sizes of 4.13 to 8.67 nm. The plate‐like Mn‐doped Ni‐Al LDH consists of many superimposed nanosheets with a size of 9.99 nm. Energy‐dispersive X‐ray and X‐ray photoelectron spectroscopies confirm the incorporation of Mn2+ into the Ni‐Al LDH. UV–vis diffuse reflectance spectroscopy results indicate that incorporating Mn2+ into LDH enhances its interaction with light. The experimental data from the batch fluoride adsorption studies are subjected to kinetic models such as pseudo‐first order and pseudo‐second order. The kinetics of fluoride retention on Ni‐Mn/Al LDH obey the pseudo‐second‐order model. The Temkin equation well describes the equilibrium adsorption of fluoride. The results from the thermodynamic studies also indicate that fluoride adsorption is exothermic and spontaneous.
Developing an evaluation approach to consider the influence of country context on environmental impact assessment performance, from a southern African perspective
Authors: Aljareo Abdulhakim , Watson Ingrid , Schwaibold Ute 
Published: April 2023

Abstract
Environmental impact assessment (EIA) as an environmental policy has been adopted in some countries. However, in terms of achieving its stated objectives in the developing country context, EIA system performance often falls short compared with the developed country context. Evaluation of EIA system performance has gained considerable attention with the aim of ensuring the achievement of its purpose, most recognizably the promotion of sustainable development through informed decision-making. Different evaluation approaches have been developed and applied to explore areas of inadequacy in the EIA system components, EIA implementation, and EIA report. Researchers have considered the context of the EIA system as the underlying cause of its limited performance in developing countries. However, the literature has not rigorously explored the relationship between EIA system performance and country context, and it is the subject of ongoing debate. Our aim in this article is to contribute to the practical analysis of the influence of country context on EIA system performance. Drawing on the conceptual frameworks and evaluation methods in the literature, we propose an evaluation approach to the EIA system performance that combines the importance of considering the country context in the evaluation process. It consists of EIA system components, EIA report, and an indicative set of country context indicators. The developed evaluation approach was validated by applying it to four case studies from southern Africa. The South African case study results are presented here. The outcome is a practical evaluation approach that promotes understanding of the relationship between EIA system performance and country context and can improve EIA system performance. Integr Environ Assess Manag 2023;19:1510–1524. © 2023 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals LLC on behalf of Society of Environmental Toxicology & Chemistry (SETAC).
Classifications of benign and malignant mammogram images using Gabor‐modified CNN architecture
Authors: Swetha V. , Vadivu G. 
Published: April 2023

AbstractBreast cancer is one of the leading life killing cancers in women patients around the world. Digital mammogram is used to detect and segment the abnormal mass portions in breast region. In this article, the breast cancer regions are detected and segmented using the Gabor transform based Convolutional Neural Networks (CNN) classification approach. This proposed breast cancer detection method consist of the following modules Kirsch's edge detector, Gabor transform, CNN classification and Segmentation. The cancer pixels and healthy pixels are differentiated in edge pixels. Hence, the Kirsch's edge detector is used to detect the fine edge boundary pixelsthe in source mammogram image. Then, the spatial edge detected mammogram image is converted into multi resolution mammogram image using Gabor transform. This transformed multi resolution mammogram image is classified into Normal, Benign or Malignant in this article using the proposed CNN architecture. The developed CNN structure extracts more complex feature maps from their internal layers to improve the classification rate. The conventional and proposed CNN structure is differed with respect to the internal layers. The proposed CNN structure is optimized by reducing the usage of the internals and increases Convolutional Filters (CF) in each Convolutional Layer during utilization design process. After classification process over, the cancer regions in the abnormal mammogram images are segmented using morphological functions. The proposed breast cancer detection is evaluated on Mammographic Image Analysis Society (MIAS) dataset and their cancer region segmentation results are 98.4% of sensitivity, 98.9% of specificity and 99.2% of cancer region segmentation accuracy. The average Detection Rate (DR) of the proposed breast cancer detection method is about 98.3% on the set of mammogramthe images from MIAS dataset. These simulation results are compared with other state‐of‐the art methods and cross verified by the k‐fold verification algorithm.
EXPRESSION OF CONCERN: Intratumoral microbiota is associated with prognosis in patients with adrenocortical carcinoma
Authors: Li Yuqing , Zhang Dengwei , Wang Minghua , Jiang Haowen , Feng Chenchen , Li Yong‐Xin 
Published: April 2023

AbstractAdrenocortical carcinoma (ACC) is a rare but aggressive malignancy. Recent studies have discovered a pivotal role of the intratumoral microbiota in various cancers, yet it remains elusive in ACC. Here, we explored the intratumoral microbiome data derived from in silico identification, further validated in an in‐house cohort by bacterial 16S rRNA fluorescence in situ hybridization and lipopolysaccharide staining. Unsupervised clustering determined two naturally distinct clusters of the intratumoral microbiome in ACC, which was associated with overall survival. The incorporation of microbial signatures enhanced the prognostic performance of the clinical stage in an immunity‐dependent manner. Genetic and transcriptomic association analyses identified significant upregulation of the cell cycle and p53 signaling pathways associated with microbial signatures for worsened prognosis. Our study not only supports the presence of intratumoral bacteria but also implies a prognostic and biological role of intratumoral microbiota in ACC, which can advance a better understanding of the biology of ACC.
Impact of pharmacist‐led discharge medication reconciliation at an Academic Medical Center
Authors: Clark Collin M. , Carden Dominick , Seyse Stephanie , Cieri‐Hutcherson Nicole E. , Woodruff Ashley E. 
Published: April 2023

AbstractPrior studies evaluating the impact of pharmacist‐led discharge medication reconciliation have demonstrated higher rates of medication discrepancy detection and intervention with variable effects on hospital readmission. The purpose of this study was to evaluate the impact of a newly developed pharmacist‐led hospital discharge medication reconciliation process implemented with an interdisciplinary Internal Medicine Service. This was a retrospective, single‐center, pre‐post observational cohort study. Institutional review board approval was obtained. The primary end point was quantification and categorization of medication discrepancies identified on the hospital discharge medication list. Secondary end points included characterization of interventions made during the discharge medication reconciliation process, and 30‐day hospital readmission rates that were adjusted using a multivariable logistic regression model. A total of 144 patients were included in the pharmacist‐led discharge medication reconciliation intervention group and 144 patients were included in the historical control. There was a statistically significant four‐fold reduction in the number of medication discrepancies identified on discharge medication lists in the intervention group (77 vs. 18 in the historical control vs. intervention groups, respectively; p < 0.0001). When adjusted for length of stay (L), acuity of the admission (A), comorbidity of the patient (C), and emergency department use in the last 6 months (E) (LACE) index and age, the adjusted odds ratio (aOR) for 30‐day readmission was 0.51 (95% confidence interval: 0.27–0.95) in the intervention versus the historical control group. Implementation of an interdisciplinary pharmacist‐led discharge medication reconciliation program was associated with a significant reduction in medication discrepancies on the discharge medication list, as well as a reduction in the adjusted odds of 30‐day hospital readmission.
Trauma exposure, posttraumatic stress, and identity content valences among Japanese adolescents
Authors: Hihara Shogo , Truskauskaite‐Kuneviciene Inga , Abe Kazuaki , Daniunaite Ieva , Haramaki Yutaka , Kazlauskas Evaldas , Sugimura Kazumi , Zelviene Paulina , Kabir Russell S. , Masuda Narumi , Kamite Yuka 
Published: April 2023

AbstractIntroductionTheorists and a few empirical studies have suggested that traumatic experiences, posttraumatic stress disorder (PTSD), and complex PTSD (CPTSD) may affect identity development. However, existing studies have overlooked how adolescents' traumas are associated with the alignment of their identity with socio‐cultural expectations, which is a crucial component of identity development. To address this gap, this study examined the associations of various types of potentially traumatic experiences and PTSD and CPTSD symptoms with the positive and negative valences of identity affected by desirable and undesirable images within socio‐cultural contexts.MethodsA cross‐sectional survey of 341 adolescents (44.0% girls; Mage = 14.8, SD = 1.8) was conducted in Japan.ResultsExposure to certain types of potentially traumatic events (e.g., family violence and physical attack) were related to high levels of negative identity elements, whereas none of the types were related to positive identity elements. The results also indicated that CPTSD‐specific symptoms of disturbances in self‐organization (DSO) were related to high levels of negative identity elements rather than PTSD.ConclusionsThe findings expand upon related research by suggesting that adolescents' exposure to some types of traumatic events (e.g., family violence and physical attack) and posttraumatic DSO symptoms have the potential to disturb the alignment of their identities with socio‐cultural expectations.
Examining readiness for implementing practice changes in federally qualified health centers: A rapid qualitative study
Authors: Dias Emanuelle M. , Walker Timothy J. , Craig Derek W. , Gibson Robert , Szeszulski Jacob , Brandt Heather M. , Johnson Hiluv , Lamont Andrea , Wandersman Abraham , Fernandez Maria E. 
Published: April 2023

AbstractImplementing evidence‐based interventions remains slow in federally qualified health centers (FQHCs). The purpose of this study is to qualitatively examine the R = MC2 (Readiness = motivation × innovation specific capacity × general capacity) heuristic subcomponents in the context of implementing general and colorectal cancer screening (CRCS)‐related practice changes in FQHCs. We conducted 17 interviews with FQHC employees to examine (1) experiences with successful or unsuccessful practice change efforts, (2) using approaches to promote CRCS, and (3) opinions about R = MC2 subcomponents. We conducted a rapid qualitative analysis to examine the frequency, depth, and spontaneity of subcomponents. Priority, compatibility, observability (motivation), intra‐ and interorganizational relationships (innovation‐specific capacity), and organizational structure and resource utilization (general capacity) emerged as highly relevant. For example, organizational structure was described as related to an organization's open communication during meetings to help with scheduling procedures. The results contribute to understanding organizational readiness in the FQHC setting and can be helpful when identifying and prioritizing barriers and facilitators that affect implementation.