bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dense Arrays of Nanohelices: Raman Scattering from Achiral Molecules Reveals the Near‐Field Enhancements at Chiral Metasurfaces
Authors: Jones Robin R. , Miksch Cornelia , Kwon Hyunah , Pothoven Coosje , Rusimova Kristina R. , Kamp Maarten , Gong Kedong , Zhang Liwu , Batten Tim , Smith Brian , Silhanek Alejandro V. , Fischer Peer , Wolverson Daniel , Valev Ventsislav K. 
Published: January 2023

AbstractAgainst the background of the current healthcare and climate emergencies, surface enhanced Raman scattering (SERS) is becoming a highly topical technique for identifying and fingerprinting molecules, e.g., within viruses, bacteria, drugs, and atmospheric aerosols. Crucial for SERS is the need for substrates with strong and reproducible enhancements of the Raman signal over large areas and with a low fabrication cost. Here, dense arrays of plasmonic nanohelices (≈100 nm in length), which are of interest for many advanced nanophotonics applications, are investigated, and they are shown to present excellent SERS properties. As an illustration, two new ways to probe near‐field enhancement generated with circular polarization at chiral metasurfaces are presented, first using the Raman spectra of achiral molecules (crystal violet) and second using a single, element‐specific, achiral molecular vibrational mode (i.e., a single Raman peak). The nanohelices can be fabricated over large areas at a low cost and they provide strong, robust and uniform Raman enhancement. It is anticipated that these advanced materials will find broad applications in surface enhanced Raman spectroscopies and material science.
Terahertz Nonlinear Hall Rectifiers Based on Spin‐Polarized Topological Electronic States in 1T‐CoTe2
Authors: Hu Zhen , Zhang Libo , Chakraborty Atasi , D'Olimpio Gianluca , Fujii Jun , Ge Anping , Zhou Yuanchen , Liu Changlong , Agarwal Amit , Vobornik Ivana , Farias Daniel , Kuo Chia‐Nung , Lue Chin Shan , Politano Antonio , Wang Shao‐Wei , Hu Weida , Chen Xiaoshuang , Lu Wei , Wang Lin 
Published: January 2023

AbstractThe zero‐magnetic‐field nonlinear Hall effect (NLHE) refers to the second‐order transverse current induced by an applied alternating electric field; it indicates the topological properties of inversion‐symmetry‐breaking crystals. Despite several studies on the NLHE induced by the Berry‐curvature dipole in Weyl semimetals, the direct current conversion by rectification is limited to very low driving frequencies and cryogenic temperatures. The nonlinear photoresponse generated by the NLHE at room temperature can be useful for numerous applications in communication, sensing, and photodetection across a high bandwidth. In this study, observations of the second‐order NLHE in type‐II Dirac semimetal CoTe2 under time‐reversal symmetry are reported. This is determined by the disorder‐induced extrinsic contribution on the broken‐inversion‐symmetry surface and room‐temperature terahertz rectification without the need for semiconductor junctions or bias voltage. It is shown that remarkable photoresponsivity over 0.1 A W−1, a response time of approximately 710 ns, and a mean noise equivalent power of 1 pW Hz−1/2 can be achieved at room temperature. The results open a new pathway for low‐energy photon harvesting via nonlinear rectification induced by the NLHE in strongly spin–orbit‐coupled and inversion‐symmetry‐breaking systems, promising a considerable impact in the field of infrared/terahertz photonics.
Lanthanide Upconversion Nanoplatforms for Advanced Bacteria‐Targeted Detection and Therapy
Authors: Li Zhuo , Lu Shan , Li Xingjun , Chen Zhuo , Chen Xueyuan 
Published: January 2023

AbstractThe growing crisis of antibiotic resistance calls for advanced and sustainable antibacterial strategies. In the past few years, lanthanide‐doped upconversion nanoparticles (UCNPs) with unique photophysical properties have been innovatively explored for bacterial detection and therapy, and hold promise for alleviating challenges faced in the post‐antibiotic era. In this review, the interface engineering for the bacteria‐targeted UCNP nanoplatforms is highlighted, the principles and merits of various upconversion detection strategies are discussed, and the latest progress in UCNP‐based antibacterial applications are summarized, especially in deep‐tissue infection imaging and therapy. Finally, the remaining concerns and future efforts for practical applications are put forward. This review is expected to provide comprehensive guidance for diagnosing and combating bacterial infections based on advanced UCNP nanoplatforms.
Steric Barrier‐Steered Reaction Sites in Micellar Catalysis
Authors: Zhang Lijuan , Yin Shengqiang , Guan Weijiang , Lu Chao 
Published: January 2023

AbstractIn the pursuit of an advanced micellar catalysis system, the reaction sites in micelles determine its catalytic performances. However, the intrinsic polarity gradient of micelles anchors the reactants in the fixed regions, leading to an unmet challenge to steer the reaction sites to the optimal ones. To overcome this limitation, a Förster resonance energy transfer (FRET) spectroscopic ruler is established to position the true sites of reactants in micellar catalysis by using tetraphenylethylene (TPE) in the aggregation‐induced emission (AIE) micelles as the FRET donor and Nile red as the FRET acceptor. Subsequently, the customizable TPE steric barriers in the AIE micelles are apt to mediate the reactants into the polar micellar surface, the semipolar palisade layer, or the nonpolar internal layer, achieving the corresponding catalytic efficiencies. Additionally, the universality of steric barrier‐steered reaction sites in micellar catalysis is further demonstrated by the simple incorporation of small nonpolar molecules into the commercially available surfactants. To the authors’ knowledge, this is the first report on the design of steric barriers to steer the reaction sites in micellar catalysis. These findings open up attractive perspectives for the exploration of new classes of efficient micellar catalysis systems in a variety of reactions.
Prediction of Linear Energy Transfer Based on Geant4 Simulation and Neural Networks
Authors: Zhang Xuyan , Chen Siyu , Liu Bohang , Cao Xianfa , Chen Dongliang , Ma Lan , Wang Shulong 
Published: January 2023

AbstractMost of the traditional studies based on single event effects (SEEs) favor the analysis of electrical mechanisms of semiconductor devices. Professional simulation software in microelectronics requires researchers to have a solid knowledge of microelectronics theory, and the modeling threshold of the software is relatively high, the simulation speed is slow, and accurate simulation of inter‐particle and particle–material interactions is lacking. SEEs are related to linear energy transfer (LET), in this paper, a method is proposed to obtain LET datas to predict SEEs of particles incident on silicon materials by using the Geant4 Monte Carlo toolkit in combination with a dense convolutional network to accurately and rapidly estimate the energy deposition characteristics of the particles. The proposed network structure has a high prediction accuracy with a mean square error （MSE） of only 1.77 × 10−4. Compared with Geant4, which takes 1 min to compute a set of data, the proposed network structure takes only 0.0817 s. The method explores the feasibility of using Geant4 to model semiconductor devices combined with deep learning algorithms, providing a new research perspective for the prediction of microelectronic devices and making it possible to explore the influence of integrated circuits by SEEs.
Perovskite Solar Cells in the Shadow: Understanding the Mechanism of Reverse‐Bias Behavior toward Suppressed Reverse‐Bias Breakdown and Reverse‐Bias Induced Degradation
Authors: Wang Chaofeng , Huang Like , Zhou Yike , Guo Yi , Liang Kaiwen , Wang Tianzhou , Liu Xiaohui , Zhang Jing , Hu Ziyang , Zhu Yuejin 
Published: January 2023

AbstractIn recent years, the power conversion efficiencies of halide perovskite solar cells (PSCs) have reached 25.7%. Further commercialization puts forward higher requirements for the stability of PSCs under different stresses. Current research on the stability of PSCs predominantly focuses on investigating the effects of temperature, humidity, oxygen, ultraviolet light, and electrical bias stress, while stability under reverse bias has been poorly studied among the many factors. When large‐area application of PSCs panels occurs, the shading effect and local hot spots of PSCs modules in real scenarios all indicate that the research on reverse bias stability of PSCs is urgently needed. Within this review, a bird's‐eye view of the recent advances on the reverse bias stability issue and reverse bias behavior of PSCs is obtained, and the related mechanisms behind that have been proposed so far are reviewed and discussed. Furthermore, future directions are provided for further improving the reverse bias stability of PSCs via increasing the reverse breakdown voltage (VRB). This review aims to promote the establishment of well‐established reverse bias degradation and reverse breakdown mechanisms of PSCs as well as to establish standardized test procedures for reverse bias stability issues on the road to commercialization of PSCs.
Evaluation of floral volatile patterns in the genus Narcissus using gas chromatography–coupled ion mobility spectrometry
Authors: Losch Florian , Liedtke Sascha , Vautz Wolfgang , Weigend Maximilian 
Published: January 2023

AbstractPremiseDaffodils (Narcissus, Amaryllidaceae) are iconic ornamentals with a complex floral biology and many fragrant species; however, little is known about floral plant volatile organic compounds (pVOCs) across the genus and additional sampling is desirable. The present study investigates whether the floral scent of 20 species of Narcissus can be characterized using gas chromatography–coupled ion mobility spectrometry (GC–IMS), with the aim of building a comparative pVOC data set for ecological and evolutionary studies.MethodsWe used a commercial GC–IMS equipped with an integrated in‐line enrichment system for a fast, sensitive, and automated pVOC analysis. This facilitates qualitative and (semi)‐quantitative measurements without sample preparation.ResultsThe GC–IMS provided detailed data on floral pVOCs in Narcissus with very short sampling times and without floral enclosure. A wide range of compounds was recorded and partially identified. The retrieved pVOC patterns showed a good agreement with published data, and five “chemotypes” were characterized as characteristic combinations of floral volatiles.DiscussionThe GC–IMS setup can be applied to rapidly generate large amounts of pVOC data with high sensitivity and selectivity. The preliminary data on Narcissus obtained here indicate both considerable pVOC variability and a good correspondence of the pVOC patterns with infrageneric classification, supporting the hypothesis that floral scent could represent a considerable phylogenetic signal.
Finite‐frequency output feedback MPC for Markov jump systems
Authors: Liu Yuling , Wen Jiwei , Luan Xiaoli , Liu Fei 
Published: January 2023

AbstractThis paper investigates a general design framework of dynamic output feedback model predictive control (DOFMPC) for Markov jump systems within both time and frequency domain. Such a design with guaranteed H∞ and quadratic performance is formulated by a standard semi‐definite programming (SDP), and it is achieved by employing a special congruence transformation. The SDP condition greatly reduces the computational effort by eliminating bilinear matrix inequalities or equation constraints reported in existing references. Specifically, the H∞ norm of the transfer function is optimized within three types of frequency ranges on account of generalized Kalman–Yakubovic–Popov (GKYP) lemma. The quadratic index is optimized online via SDP. Finally, we verify the feasibility and effectiveness of the proposed method from both theoretical and practical point of view.
Ökobilanz im Bauwesen – Treibhausgasemissionen praxisüblicher Deckensysteme
Authors: Heckmann Michael , Glock Christian 
Published: January 2023

AbstractIn den vergangenen Jahren erfolgte eine ökobilanzielle Bewertung von Gebäuden nur in Ausnahmefällen auf Wunsch von Projektinitiierenden. Vor dem Hintergrund des gesellschaftlichen und politischen Drucks auf ein klimagerechtes und nachhaltiges Handeln werden Ökobilanzen und die zur Verfügung stehenden Daten zunehmend auch wirtschaftlich relevant. Im Rahmen des Beitrags werden daher die wesentlichen Grundlagen einer Ökobilanz im Bauwesen vorgestellt. Neben einer kritischen Analyse des Bilanzierungsrahmens erfolgt eine kurze Vorstellung verfügbarer Datengrundlagen, wie z. B. der nationalen Datenbank ÖKOBAUDAT. Ferner wird auf die Treibhausgasbilanzierung des Baustoffs Holz eingegangen, die teils erhebliche Bewertungsspielräume mit der Gefahr von Fehlanreizen eröffnet. Als horizontale Bauteile können Deckensysteme von mehrgeschossigen Bauten etwa 40 % der tragwerksbedingten Emissionen eines Gebäudes verursachen und sind folglich von hoher Relevanz für eine Ökobilanz. Unter Variation der bilanzierten Lebenszyklusphasen und verwendeten Datensätze als mögliche Einflussfaktoren auf die Ergebnisse einer Ökobilanz werden diese Bauteile im nachfolgenden Beitrag genauer untersucht und gegenübergestellt. Trotz z. T. sensibler Auswirkungen auf die Gegenüberstellung der Deckensysteme bietet die Ökobilanz eine klare Entscheidungshilfe bei der Wahl von Deckensystemen im Sinne reduzierter Treibhausgasemissionen einer Rohbaukonstruktion.
Modification of the swirling well cell culture model to alter shear stress metrics
Authors: Arshad Mehwish , Cheng Shuyu , van Reeuwijk Maarten , Sherwin Spencer J. , Weinberg Peter D. 
Published: January 2023

AbstractEffects of hemodynamic shear stress on endothelial cells have been extensively investigated using the “swirling well” method, in which cells are cultured in dishes or multiwell plates placed on an orbital shaker. A wave rotates around the well, producing complex patterns of shear. The method allows chronic exposure to flow with high throughput at low cost but has two disadvantages: a number of shear stress characteristics change in a broadly similar way from the center to the edge of the well, and cells at one location in the well may release mediators into the medium that affect the behavior of cells at other locations, exposed to different shears. These properties make it challenging to correlate cell properties with shear. The present study investigated simple alterations to ameliorate these issues. Flows were obtained by numerical simulation. Increasing the volume of fluid in the well‐altered dimensional but not dimensionless shear metrics. Adding a central cylinder to the base of the well‐forced fluid to flow in a square toroidal channel and reduced multidirectionality. Conversely, suspending a cylinder above the base of the well made the flow highly multidirectional. Increasing viscosity in the latter model increased the magnitude of dimensional but not dimensionless metrics. Finally, tilting the well changed the patterns of different wall shear stress metrics in different ways. Collectively, these methods allow similar flows over most of the cells cultured and/or allow the separation of different shear metrics. A combination of the methods overcomes the limitations of the baseline model.
Continuous flow system for biphasic synthesis of gem‐dichloroaziridine derivatives
Authors: Jang Yea Seul , Kang Kook Hee , Yun Seula , Park Chan Pil 
Published: January 2023

Abstractgem‐Dichloroaziridines are essential building blocks in the synthesis of biologically and pharmacologically active compounds. We developed a continuous flow biphasic system to overcome the limitation of conventional batch systems, in which dichlorocarbene generated from the reaction of chloroform and a NaOH combined with azomethines to generate gem‐dichloroaziridine derivatives in good yields. Then a two‐step one‐flow process was designed with the addition of flow synthesis of N‐benzylideneaniline. This process is also advantageous in protecting the researcher from irritating odors and harmful reactants and intermediates.
Semi‐Synthesis of Flavonoid Glycosides and Their Anti‐Inflammatory and Antitumor Activities towards Triple Negative Breast Cancer
Authors: Xie Ji‐Zhao , Xu Huan‐Ji , Zhang Qing , Wu Zheng , Wu Xin‐Duo , Li Xue‐Hua , Tan Zhen‐Yuan , Xie Yun‐Feng , Qiu Li 
Published: January 2023

AbstractBackground: Flavonoid glycosides are known to possess diverse bioactivities including antitumor and anti‐inflammatory properties. Hesperetin is abundant in nature and can be used to synthesize bioactive flavonoids. This has the advantages of low cost, short synthetic steps, simple operation, and good yields. Objective: In this study, we aimed to synthesize bioactive flavonoids and flavonoid glycosides from hesperetin and evaluate the antitumor and anti‐inflammatory activities of these compounds. Methods: A series of flavonoids and their derivatives were synthesized by methoxylation, oxidative dehydrogenation, benzylation, debenzylation, and deacetylation as well as using a modified peroxyacetone method and a glycoside condensation reaction. Their anti‐inflammatory activities were evaluated for their inhibitory effects on nitric oxide (NO), tumor necrosis factor (TNF‐α), and interleukin‐6 (IL‐6) production in LPS‐induced RAW264.7 mouse macrophages. Their structures were characterized by HRMS, 1H‐NMR, and 13C‐NMR, and their cytotoxicity on the human triple‐negative breast cancer cell (TNBC) line, SUM 149, was tested by using the MST assay. Results: Most of the compounds markedly reduced NO production in LPS‐stimulated murine macrophages at the tested concentrations in a dose‐dependent manner. Among these, compounds 1, 7, 9, and 17 showed significant anti‐inflammatory activities against NO production in LPS‐induced RAW264.7 mouse macrophages. In addition, they could also reduce the release of TNF‐α and IL‐6 in a concentration‐dependent manner. Most of the tested compounds showed remarkable anti‐human TNBC activities. Compounds 1b–1m, 1, and 3 showed a certain degree of growth inhibition effect on the human TNBC cell lines and their IC50 values were all below 16.61 μM. In addition, compound 1l was the most cytotoxic with IC50 values of 1.38±0.31 μM, while the other compounds were inactive with inhibition rates <50 % at the highest concentration tested (20 μM). Conclusions: A novel series of flavonoids were synthesized from the natural flavonoid, hesperetin, including 17 new compounds. Screening tests indicated that most of these compounds reduced NO production in LPS‐stimulated murine macrophages at concentrations of 15 to 60 μM, and the inhibition generally increased in a dose‐dependent manner. Some compounds showed different degrees of cytotoxicity on the human TBNC cell lines, SUM 149.
Pituitary hyposignal characteristic of hemochromatosis on MRI
Authors: Yehouenou Tessi Romeo Thierry , Oze Rita Koudouhonon , Outznit Mustapha , Hadj Hsain Ihssan , Nassar Ittimade , Moatassim Billah Nabil 
Published: January 2023

AbstractPituitary haemochromatosis is an endocrine disorder caused by the accumulation of iron due to a lack of absorption during haemochromatosis. The characteristic appearance on MRI is a T2 and T2* hyposignal of the anterior pituitary gland without enhancement, respecting the pituitary stalk and the posterior pituitary gland.
A giant quiet esophageal polyp: A case report
Authors: Sadidi Hossein , Ahmadi Ghazale , Mehri Ali , Nouri Dalouee Marzie 
Published: January 2023

AbstractFibrovascular polyps of the esophagus are rare, benign, intraluminal submucosal tumors. In this report, we present a case of esophageal polyp in a young woman and discuss its diagnostic and surgical aspects.
Neutrophilic erythrophagocytosis in myelodysplastic syndrome and cold agglutinin disease co‐occurrence
Authors: Amelirad Asra , Modaresi Parisa , Soltani Hassan 
Published: January 2023

AbstractIn this article, we report the rare phenomenon of erythrophagocytosis by neutrophils in peripheral blood smear of a 56‐year‐old male patient with concurrent myelodysplastic syndrome and cold agglutinin disease.
Sulphonic Acid‐Functionalized Polymeric Ionic Liquids Catalyzed Conversion of Carbohydrates into Levulinic Acid in One‐Pot Reaction
Authors: Shi Shengbin , Wu Wenting , Liu Panli , Xiao Guomin 
Published: January 2023

AbstractSulphonic acid‐functionalized polymeric ionic liquids (PILs) were synthesized and applied into catalytic conversion of cellulose into levulinic acid (LA). The structure, thermal stability, and Hammett acidity function (H0) of PILs were characterized and all were more thermostable than those of small‐molecular ionic liquids (IL). At the optimum reaction conditions, the LA yield was maximized to 79.4 % by catalyst [Pim]CH3SO3. More importantly, catalyst [Pim]CH3SO3 performed well in other biomass conversion, such as cellobiose, starch and rice husk. The product LA can be easily extracted by methyl isobutyl ketone from the reaction mixture. The PILs with high catalytic activity were easily recycled with an LA yield up to 68.9 % even after five cycles. These sufficient PILs will offer new approaches for transforming biomass to platform chemicals.
Soluble Iron Enhances Extracellular Electron Uptake by Shewanella oneidensis MR‐1
Authors: Abuyen Karla , El‐Naggar Mohamed Y. 
Published: January 2023

AbstractExtracellular electron transfer (EET) is a process that microorganisms use to reduce or oxidize external insoluble electron acceptors or donors. Much of our mechanistic understanding of this process is derived from studies of transmembrane cytochrome complexes and extracellular redox shuttles that mediate outward EET to anodes and external electron acceptors. In contrast, there are knowledge gaps concerning the reverse process of inward EET from external electron donors to cells. Here, we describe a role for soluble iron (exogenous FeCl2) in enhancing EET from cathodes to the model EET bacterium Shewanella oneidensis MR‐1, with fumarate serving as the intracellular electron acceptor. This iron concentration‐dependent electron uptake was eradicated upon addition of an iron chelator and occurred only in the presence of fumarate reductase, confirming an electron pathway from cathodes to this periplasmic enzyme. Moreover, S. oneidensis mutants lacking specific outer membrane and periplasmic cytochromes exhibited significantly decreased current levels relative to wild‐type. These results indicate that soluble iron can function as an electron carrier to the EET machinery of S. oneidensis.
Electrochemical Synthesis of Carbon Quantum Dots
Authors: Rocco Daniele , Moldoveanu Vyali Georgian , Feroci Marta , Bortolami Martina , Vetica Fabrizio 
Published: January 2023

AbstractCarbon quantum dots (CDs) are “small” carbon nanostructures with excellent photoluminescence properties, together with low‐toxicity, high biocompatibility, excellent dispersibility in water as well as organic solvents. Due to their characteristics, CDs have been studied for a plethora of applications as biosensors, luminescent probes for photodynamic and photothermal therapy, fluorescent inks and many more. Moreover, the possibility to obtain carbon dots from biomasses and/or organic waste has strongly promoted the interest in this class of carbon‐based nanoparticles, having a promising impact in the view of circular economy and sustainable processes. Within this context, electrochemistry proved to be a green, practical, and efficient method for the synthesis of high‐quality CDs, with the possibility to fine‐tune their characteristics by changing operational parameters. This review outlines the principal and most recent advances in the electrochemical synthesis of CDs, focusing on the electrochemical set‐up optimization.