bluuebunny/crossref_metadata_2025_split huggingface dataset:
Eating disorder symptomatology among transgender individuals: a systematic review and meta-analysis
Authors: Rasmussen Sofie M. , Dalgaard Martin K. , Roloff Mia , Pinholt Mette , Skrubbeltrang Conni , Clausen Loa , Kjaersdam Telléus Gry 
Published: May 2023

Abstract
Objective
The purpose of this systematic review and meta-analysis was to synthesize the literature on eating disorders and eating disorder symptomatology among transgender individuals and to summarize the existing literature on gender-affirming treatment and the prevalence of eating disorder symptomatology.

Method
The literature search for this systematic review and meta-analysis was performed in PubMed, Embase.com, and Ovid APA PsycInfo. We searched for “eating disorders” and “transgender” using both controlled vocabularies and natural language terms for their synonyms. The PRISMA statement guidelines were followed. Quantitative data from studies on transgender individuals and eating disorders assessed with relevant assessment tools was included.

Results
Twenty-four studies were included for the qualitative synthesis, and 14 studies were included in the meta-analysis. The results revealed higher levels of eating disorder symptomatology among transgender individuals compared with cisgender individuals, especially cisgender men. Transgender men tend to display higher levels of eating disorder symptomatology than transgender women; however, transgender women seem to have higher levels of eating disorder symptomatology than cisgender men and, interestingly, this study also noted a trend toward transgender men having higher levels of eating disorders than cisgender women. Gender-affirming treatment seems to alleviate the presence of eating disorder symptomatology in transgender individuals.

Discussion
The body of research on this subject is extremely limited, and transgender individuals are underrepresented in the eating disorder literature. More research investigating eating disorders and eating disorder symptomatology in transgender individuals and the relationship between gender-affirming treatment and eating disorder symptomatology is needed.
School socio-economic context and student achievement in Ireland: an unconditional quantile regression analysis using PISA 2018 data
Authors: Flannery Darragh , Gilleece Lorraine , Clavel Jose G. 
Published: May 2023

Abstract
Background
The existence of a multiplier, compositional or social context effect is debated extensively in the literature on school effectiveness and also relates to the wider issue of equity in educational outcomes. However, comparatively little attention has been given to whether or not the association between student achievement and school socio-economic composition may vary across the achievement distribution. Furthermore, with limited exception, comparatively little use has been made of unconditional quantile modelling approaches in the education literature.

Methods
This paper uses Irish data from the Programme for International Student Assessment 2018 and employs ordinary least squares regression and unconditional quantile regression empirical approaches to examine the association between school socio-economic composition and achievement. Reading and mathematics achievement are used as outcome variables and models control for a rich set of school and student characteristics.

Results
Findings from the ordinary least squares regression show that, on average, there is a significant negative relationship between school socio-economic disadvantage and student achievement in reading and mathematics having controlled from a range of individual and school-level variables. From a distributional perspective, unconditional quantile regression results show variation in the strength of the relationship between school socio-economic disadvantage and student achievement, particularly in reading, with a stronger association at the lower end of the achievement distribution. Findings illustrate the need to give nuanced consideration to how students with varying levels of achievement may experience a socio-economically disadvantaged context at school. Our findings also draw attention to the benefit of examining variation in the association between achievement and explanatory variables across the achievement distribution and underscore the importance of moving beyond an exclusive focus on the mean of the distribution. Finally, we emphasise the importance of drawing population-level inferences when using the unconditional quantile regression method.
Bioupgrading of the aqueous phase of pyrolysis oil from lignocellulosic biomass: a platform for renewable chemicals and fuels from the whole fraction of biomass
Authors: Ashoor Selim , Khang Tae Uk , Lee Young Hoon , Hyung Ji Sung , Choi Seo Young , Lim Sang Eun , Lee Jinwon , Park Si Jae , Na Jeong-Geol 
Published: May 2023

AbstractPyrolysis, a thermal decomposition without oxygen, is a promising technology for transportable liquids from whole fractions of lignocellulosic biomass. However, due to the hydrophilic products of pyrolysis, the liquid oils have undesirable physicochemical characteristics, thus requiring an additional upgrading process. Biological upgrading methods could address the drawbacks of pyrolysis by utilizing various hydrophilic compounds as carbon sources under mild conditions with low carbon footprints. Versatile chemicals, such as lipids, ethanol, and organic acids, could be produced through microbial assimilation of anhydrous sugars, organic acids, aldehydes, and phenolics in the hydrophilic fractions. The presence of various toxic compounds and the complex composition of the aqueous phase are the main challenges. In this review, the potential of bioconversion routes for upgrading the aqueous phase of pyrolysis oil is investigated with critical challenges and perspectives.
Graphical Abstract
Further development in measuring communicative participation: identifying items to extend the applicability of the communicative participation item bank
Authors: ter Wal Nicole , van Ewijk Lizet , Visser-Meily Johanna M.A. , Volkmer Anna , Gerrits Ellen , Terwee Caroline B. 
Published: May 2023

Abstract
Background
The ability to communicate is a prerequisite for participation in today’s society. To measure participation in adults with communication disorders, the Communicative Participation Item Bank (CPIB) was developed in 2006. Since then, several new PROMs have been developed to measure communication and the impact of communication disorders on participation. Moreover, the CPIB items do not all appear to be relevant to certain populations with communication problems and context of communicative participation is changing rapidly, given the increased use of digital communication forms. The purpose of this study was to identify new PROMs developed since 2006 that aim to measure (aspects of) communication, in order to select items that are suitable for expanding the Communicative Participation Item Bank to make the item bank more widely applicable (e.g., to the hearing-impaired population) and tailored to the current societal context.

Methods
Medline and Embase were used to search for PROMs that aim to measure (aspects of) communication. Each new PROM as well as the CPIB, was evaluated to determine to what extent it contains items that measure communicative participation and to what extent these items capture all communicative participation domains by linking each item to the ICF Activities and Participation domains.

Results
This study identified 31 new PROMs, containing 391 items that were labelled as measuring communicative participation. The majority of the 391 items measure aspects of ICF Activities and Participation domain ‘communication’, followed by the domain ‘interpersonal interactions and relationships’. The other ICF Activity and Participation domains were less often addressed. Analysis of the CPIB showed that items do not cover all domains of participation as defined in the ICF, such as the ‘major life areas’ domain.

Conclusions
We found a potential pool of 391 items measuring communicative participation that could be considered for extending the CPIB. We found items in domains that are already present in the CPIB, but also items that relate to new domains, such as an item on talking with customers or clients for the ‘major life areas’ domain. Inclusion of new items in other domains would benefit the comprehensiveness of the item bank.
Combination of decaffeinated green coffee and decaffeinated green tea ameliorates cardiomyopathy through cardiotrophin-1-dependent expression regulation in a metabolic syndrome rat model: a proposed mechanism
Authors: Rohman Mohammad Saifur , Lukitasari Mifetika , Kholis Mukhamad Nur , Wahyuni Nila Aisyah , Chandra Beryl Reinaldo , Hermanto Feri Eko , Widodo Nashi 
Published: May 2023

Abstract
Background
Cardiovascular diseases (CVD) are the primary medical manifestation of metabolic syndrome (MetS). Hypoxia is also involved in the pathogenesis of CVD. Since dietary intervention significantly improved the physiological condition in MetS, the development of functional food to complement conventional medical therapy is essential. Among several standard consumable products, decaffeinated green tea (DGT) and decaffeinated green coffee (DGC) have excellent activity in managing MetS-induced CVD. However, the mechanism underlying their protective activity is poorly understood. This study aimed to understand the cardio-protective activity of DGT, DGC, and a combination of the two (DGT + DGC) in managing MetS-induced CVD in vivo and in silico.

Results
The MetS condition led to the upregulation of Cardiotrophin-1 (CT-1), Signal Transducer and Activator of Transcription 3 (STAT3), GATA binding protein 4 (GATA4), and B-type Natriuretic Peptide (BNP) beyond the levels of the normal (N) group, while administration of DGT, DGC, and DGT + DGC significantly decreased the expression of those genes compared with the levels of the N group (p < 0.05). The computational analysis showed that the protective role of DGT, DGC, and DGT + DGC might be achieved through AKT1 inhibition by several bioactive components present in DGT and DGC. The analysis also defined the improvement in cardio-protective activity by combining DGT and DGC.

Conclusions
The administration of DGT, DGC, or DGT + DGC repaired cardiac dysfunction parameters through indirect regulation of the CT-1 signaling axis by inhibiting AKT1 activity.
Validation of RUBY for Breast Cancer Knowledge Extraction From a Large French Electronic Medical Record System
Authors: Schiappa Renaud , Contu Sara , Culie Dorian , Chateau Yann , Gal Jocelyn , Pace-Loscos Tanguy , Bailleux Caroline , Haudebourg Juliette , Ferrero Jean-Marc , Barranger Emmanuel , Chamorey Emmanuel 
Published: May 2023

PURPOSE RUBY is a tool for extracting clinical data on breast cancer from French medical records on the basis of named entity recognition models combined with keyword extraction and postprocessing rules. Although initial results showed a high precision of the system in extracting clinical information from surgery, pathology, and biopsy reports (≥92.7%) and good precision in extracting data from consultation reports (81.8%), its validation is needed before its use in routine practice. METHODS In this work, we analyzed RUBY's performance compared with the manual entry and we evaluated the generalizability of the approach on different sets of reports collected on a span of 40 years. RESULTS RUBY performed similarly or better than the manual entry for 15 of 27 variables. It showed similar performances when structuring newer reports but failed to extract entities for which changes in terminology appeared. Finally, our tool could automatically structure 15,990 reports in 77 minutes. CONCLUSION RUBY can automate the data entry process of a set of variables and reduce its burden, but a continuous evaluation of the format and structure of the reports and a subsequent update of the system is necessary to ensure its robustness.
Faulkner's Glitches
Authors: Wainstein Nathan 
Published: May 2023

Abstract
Formalist novel criticism has a strange relationship to artistic failure. Although an array of twentieth-century theoretical frameworks have taught critics to find value and meaning in negative formal phenomena that may resemble writerly lapses (such as moments of contradiction, discontinuity, or ambiguity), the same critics rarely make actual negative judgments about literary form. This article examines and challenges this critical trend. It begins by introducing the new formal category of the narrative glitch: a microscopic disruption of fictional mimesis that resembles both a formal experiment and a simple writerly failure. It then turns to the work of William Faulkner, whose novels Sanctuary and Absalom, Absalom! reveal a buried alliance between criticism's customary ways of understanding glitches and an older modernist aesthetics. In Absalom, Absalom!, General Compson's celebratory close reading of a temporal rupture in Thomas Sutpen's narrative models an essentially modernist trope of glitch interpretation (the aesthetic redemption of a formal rupture as temporally mimetic) that remains popular in criticism to this day. At the same time, Faulkner's own glitches in Sanctuary, when read as genuine writerly lapses, dramatize the fallibility of this enduring critical gesture and thus subvert and estrange criticism's latent modernism.
Neoliberal Kosmos and the Cunning of Aesthetic Revolt
Authors: Bailey Devan 
Published: May 2023

Abstract
Writing in The Fatal Conceit: The Errors of Socialism (1988) late in his career, the neoliberal theorist F. A. Hayek lamented that writers and artists of his time had remained under the spell of “constructivist rationalism.” The truth, however, is more interesting. Sharing Theodor W. Adorno's fear that the “administered world” that arose in the twentieth century might “strangle all spontaneity,” artists embraced chance, open-endedness, and indeterminacy. In the process, experimental artists went beyond negating the rationalized postwar social order; their work also positively modeled the dispersed, unwilled—in a word, spontaneous—conception of social order that simultaneously came to theoretical expression in the work of neoliberal intellectuals. This essay offers new insight into the formal unity between spontaneous aesthetics and the neoliberal account of the order produced by markets. After broadly retracing the shared commitment among experimental artists and neoliberal intellectuals to spontaneous order—that is, to order as an emergent effect of dispersed activity rather than the rational outcome of conscious construction and coordination—this essay reads Jacques Attali's Noise: The Political Economy of Music (1977) as a text in which the spirit of aesthetic revolt formally and materially converges with the neoliberal intellectual and political project.
Lack of expression of miR-29a/b1 impairs bladder function in male mice
Authors: Wang Zunyi , Spitz Robert , Vezina Chad , Hou Jianghui , Bjorling Dale E. 
Published: May 2023

ABSTRACT
Lower urinary tract symptoms (LUTS) refer to various urological diseases, and incomplete bladder emptying is common among affected patients. The etiology of LUTS is largely unknown, and investigations of LUTS suggest that bladder fibrosis contributes to pathogenesis of LUTS. MicroRNAs (miRNAs) are short (∼22 nucleotides), non-coding RNAs that repress target gene expression by a combination of mRNA degradation and translation inhibition. The miR-29 family is best known for its anti-fibrotic role in various organs. miR-29 was decreased in bladders of patients with outlet obstruction and a rat model of bladder outlet obstruction, suggesting that miR-29 may contribute to impaired bladder function subsequent to tissue fibrosis. We characterized bladder function in male mice lacking expression of Mir29a and Mir29b-1 (miR-29a/b1). Lack of miR-29a/b1 resulted in severe urinary retention, increased voiding duration and reduced flow rate, and these mice failed to void or voided irregularly during anesthetized cytometry. Collagens and elastin were increased in bladders of mice lacking miR-29a/b1. These findings reveal an important role for miR-29 in bladder homeostasis and suggest the therapeutic potential of miR-29 to improve symptoms in patients with LUTS.
Synthesis of Photochromic Heterocyclic-Fused Naphthopyrans. Tuning the Color and Fading Speed
Authors: Graça Vânia , Sousa Céu M , Coelho Paulo J 
Published: May 2023

Abstract
New photochromic 3-thienyl-3H-naphtho[1,2-b]pyrans fused to lactone and indole rings were efficiently prepared using a one-pot acid-catalyzed reaction, at room temperature, as the key step. These colorless photoswitches acquire intense red/brown shades under UV light and return spontaneously to the colorless state in the dark. The combination of the 3 heterocyclic rings assures a broad and intense absorption in the visible region and it allows a full switch between the two states in less than 1 min, at room temperature.
Generador axial para un generador eólico de baja potencia, selección, diseño y simulación en COMSOL multiphysic
Authors: Piracoca-Peralta Sindy Tatiana , Rivas-Trujillo Edwin , Montaña-Quintero Henry 
Published: May 2023

Los generadores de flujo axial son máquinas utilizadas en sistemas de generación eólica, y dado el creciente interés por las energías renovables a pequeña escala se requiere buscar nuevas configuraciones que permitan enfrentar el aumento de las necesidades energéticas a nivel mundial. En este documento se analiza la selección, diseño y simulación de tres topologías de un generador de imanes permanentes de flujo axial de doble rotor para aplicaciones de baja velocidad y baja potencia (10 watios), las cuales se modelan aplicando el método de elementos finitos en el software COMSOL 2D, como aporte al proyecto de investigación Topologías de Generador Eólico de Baja Potencia, gracias a este método es posible optimizar el diseño y observar la densidad de flujo magnético en los dientes del estator, entrehierro y polos magnéticos. Los resultados obtenidos se comparan tomando como referencia la potencia de salida generada bajo las cargas de 10, 40,100, 150 y 260 ohmios, además indican que las topologías 1 y 3 (puramente sin núcleo y estado ranurado) presentan un mejor comportamiento tanto en vacío como bajo carga, al buscar reducir el peso de la maquina implementado una matriz tipo HALBACH en los polos magnéticos de los rotores.
Chitosan nanoparticles loaded with mesosulfuron methyl and mesosulfuron methyl + florasulam + MCPA isooctyl to manage weeds of wheat (Triticum aestivum L.)
Authors: Khan Bilal Ahmad , Nadeem Muhammad Ather , Iqbal Mudassar , Yaqoob Neelam , Javaid Muhammad Mansoor , Maqbool Rizwan , Elnaggar Nehal , Oraby Hesham 
Published: May 2023

Abstract
Nanoherbicides are articulated by empowering the potential of nanotechnology for the efficacious delivery of chemical or biological herbicides with the aid of nanomaterial‐based herbicide combinations. Therefore, the goal of this work was to investigate the chitosan nanoparticles loaded with mesosulfuron methyl and mesosulfuron methyl + florasulam + (2-methyl-4-chlorophenoxyacetic acid) MCPA isooctyl herbicides as a possible environmentally benign substitute to manage weeds in wheat. Due to intriguing characteristics including biocompatibility, low allergenicity, biodegradability, and nontoxicity, chitosan biopolymers as sustainable chitin derivatives have received intense scrutiny in the biomedical business. The manufactured nanoparticles were characterized by using ultraviolet absorbance, scanning electron microscopy (SEM), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FT-IR). The average particle size as revealed by SEM was 40–70 nm in a cluster form with the porous structure. The maximum absorption peaks of both nanoparticles of mesosulfuron methyl and mesosulfuron methyl + florasulam + MCPA isooctyl were 330 and 360 nm. The FT-IR analysis showed an intensive peak at 2θ value of 30.55° for mesosulfuron methyl and 32.79° for mesosulfuron methyl + florasula + MCPA isooctyl, which correspond to the 78 and 198 planes of the anatase phase, respectively. The nanoparticles were sprayed at the third to fourth leaf stages of the targeted weeds. Seven different doses were applied. A total of 100% mortality and visual injury were caused by the chitosan-based nanoparticles of both herbicides at the recommended dose of standard herbicide. The 5-fold lower dose showed the minimum chlorophyll content (5.75%), plant height (2.35 cm), fresh biomass (1.08 g), and dry biomass (0.33 g) of a weed mixture. For the same traits, the herbicide nanoparticles at 10-fold lower dose of commercial herbicides exhibited a similar effect as the recommended dose. Nanoherbicides could recuperate the conventional herbicide effectiveness by enhancing the stability and reducing the toxicity.
Multigenic prognosis assessment model for nasopharyngeal carcinoma via a modified meta-analysis approach
Authors: Sim Chor-Chien , Ui-Hang Sim Edmund , Lee Choon-Weng , Narayanan Kumaran 
Published: May 2023

Abstract

Objectives
Currently, clinically relevant multigene-based prognostic assessment models for nasopharyngeal carcinoma (NPC) are limited. This paper reports a novel NPC prognosis assessment model based on multiple established NPC-associated biomarkers.

Methods
We used a modified meta-analysis approach to retrieve eligible studies and analyse the data. Different prognostic biomarkers and hazard ratios (HRs) with 95 % confidence intervals (CIs) of overall survival (OS) data were extracted and tabulated from eligible studies. We then used the formula based on Parmar et al. to determine OS (expressed as HR with 95 % CI). Prognosis assessment risk scores assigned to the logarithm of HR were the basis for interpreting the multigene prognosis assessment model. Finally, we explained the biological significance of this model using a multigenic NPC oncogenesis network system.

Results
We constructed a multigenic NPC prognosis assessment model consisting of 10 prognostic biomarkers to determine the OS rate in NPC patients. Based on the biomarkers’ expression patterns, the model could determine 1,023 possible OS rates of NPC patients. The risk score derived determines the prognosis status of the NPC patients. The higher the total risk assessment score, the poorer the prognosis. An NPC-associated network involving all ten biomarkers was also derived.

Conclusions
We provided a novel multigenic NPC prognosis assessment model comprising ten prognostic biomarkers on OS rate in NPC patients. A conceptual molecular-based pathophysiological network of NPC oncogenesis supported the biological relevance of this model.