bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comprehensive evaluation of the influence of sex differences on composite disease activity indices for rheumatoid arthritis: results from a nationwide observational cohort study
Authors: Nishino Takahiro , Hashimoto Atsushi , Tohma Shigeto , Matsui Toshihiro 
Published: March 2023

AbstractBackgroundThe effects and their magnitudes of sex on disease activity indices for rheumatoid arthritis are not clear. We aimed to comprehensively evaluate the influence of sex on disease activity indices in the real-world setting using a large observational database.MethodsWe analyzed 14,958 patients registered in the National Database of Rheumatic Diseases in Japan (NinJa) in 2017. We evaluated the sex differences in the 28-joint disease activity score (DAS28) using erythrocyte sedimentation rate (ESR), DAS28 using C-reactive protein (DAS28-CRP), Simplified Disease Activity Index (SDAI), and Clinical Disease Activity Index by disease activity category using Cliff’s delta and regression analysis. Differences in the share of components of indices were evaluated using permutational multivariate analysis of variance. Correction equations were constructed to estimate the number of misclassification in male patients who achieve DAS28-ESR remission.ResultsDAS28-ESR showed higher values in female patients than male patients in remission despite no obvious difference in other indices or disease activity categories. Among the components of DAS28-ESR, only ESR was higher in female patients than male patients in remission. In DAS28-CRP and SDAI, 28-tender joint count was higher and CRP was lower in female patients than male patients. In addition, the profiles in the components were different between female and male patients, especially among those with high disease activity. Using correction equations, almost 12% of male patients with DAS28-ESR remission were estimated to be misclassified, mainly due to differences in ESR.ConclusionAmong the disease activity indices, significant sex difference was observed only in DAS28-ESR remission. The degree of misclassification in DAS28-ESR remission would be unignorable.
Novel Prognostic Staging System for Patients With De Novo Metastatic Breast Cancer
Authors: Plichta Jennifer K. , Thomas Samantha M. , Hayes Daniel F. , Chavez-MacGregor Mariana , Allison Kimberly , de los Santos Jennifer , Fowler Amy M. , Giuliano Armando E. , Sharma Priyanka , Smith Benjamin D. , van Eycken Elizabeth , Edge Stephen B. , Hortobagyi Gabriel N. 
Published: March 2023

PURPOSE Given the heterogeneity and improvement in outcomes for metastatic breast cancer (MBC), we developed a staging system that refines prognostic estimates for patients with metastatic cancer at the time of initial diagnosis, de novo MBC (dnMBC), on the basis of survival outcomes and disease-related variables. METHODS Patients with dnMBC (2010-2016) were selected from the National Cancer Database (NCDB). Recursive partitioning analysis (RPA) was used to group patients with similar overall survival (OS) on the basis of clinical T category, grade, estrogen receptor (ER), progesterone receptor, human epidermal growth factor receptor 2, histology, organ system site of metastases (bone-only, brain-only, visceral), and number of organ systems involved. Three-year OS rates were used to assign a final stage: IVA: >70%, IVB: 50%-70%, IVC: 25 to <50%, and IVD: <25%. Bootstrapping was applied with 1,000 iterations, and final stage assignments were made based on the most commonly occurring assignment. Unadjusted OS was estimated. Validation analyses were conducted using SEER and NCDB. RESULTS At a median follow-up of 52.9 months, the median OS of the original cohort (N = 42,467) was 35.4 months (95% CI, 34.8 to 35.9). RPA stratified patients into 53 groups with 3-year OS rates ranging from 73.5% to 5.7%; these groups were amalgamated into four stage groups: 3-year OS, A = 73.2%, B = 61.9%, C = 40.1%, and D = 17% (log-rank P < .001). After bootstrapping, the survival outcomes for the four stages remained significantly different (log-rank P < .001). This staging system was then validated using SEER data (N = 20,469) and a separate cohort from the NCDB (N = 7,645) (both log-rank P < .001). CONCLUSION Our findings regarding the heterogeneity in outcomes for patients with dnMBC could guide future revisions of the current American Joint Committee on Cancer staging guidelines for patients with newly diagnosed stage IV disease. Our findings should be independently confirmed.
A rare case of incidentally diagnosed pulmonary inflammatory myofibroblastic tumour with dramatic response to crizotinib in a postpartum woman
Authors: Yorke Jojo , Solanki Krupa , Theegala Vaishnavi , Sinha Alok , Asberry Don , El Abbassi Adel 
Published: March 2023

Introduction: Inflammatory myofibroblastic tumours are rare neoplasms which most commonly affect children and young adults. With an intermediate malignant potential, they are typically detected in the abdomen, lung, mediastinum, head and neck, gastrointestinal tract, and genitourinary tract. Case description: We describe the case of a 33-year-old postpartum woman incidentally diagnosed with a pulmonary inflammatory myofibroblastic tumour following complaints of poorly controlled hypertension a week after caesarean section. She was ALK-negative and received an ALK inhibitor with complete resolution of the lesion. A ROS1–TFG fusion confirmed the diagnosis of an inflammatory myofibroblastic tumour after CT-guided fine needle aspiration. Discussion: This case highlights an uncommon presentation posing a diagnostic and therapeutic challenge and the potential treatment option of crizotinib.
Effect of the bonding layer and multigrading layers on the performance of a wafer-bonded InGaAs/Si single-photon detector
Authors: Chen Xiaoqiang , Jiao Jinlong , Yao Liqiang , Ji Ruoyun , Rao Yingjie , Wei Huang , Lin Guangyang , Li Cheng , Ke Shaoying , Chen Songyan 
Published: March 2023

A wafer-bonded InGaAs/Si avalanche photodiode (APD) at a wavelength of 1550 nm was theoretically simulated. We focused on the effect of the In1−xGa
x
As multigrading layers and bonding layers on the electric fields, electron and hole concentrations, recombination rates, and energy bands. In this work, In1−xGa
x
As multigrading layers inserted between Si and InGaAs were adopted to reduce the discontinuity of the conduction band between Si and InGaAs. A bonding layer was introduced at the InGaAs/Si interface to isolate the mismatched lattices to achieve a high-quality InGaAs film. In addition, the bonding layer can further regulate the electric field distribution in the absorption and multiplication layers. The wafer-bonded InGaAs/Si APD, structured by a polycrystalline silicon (poly-Si) bonding layer and In1−xGa
x
As multigrading layers (x changes from 0.5 to 0.85), displayed the highest gain-bandwidth product (GBP). When the APD operates in Geiger mode, the single-photon detection efficiency (SPDE) of the photodiode is 20%, and the dark count rate (DCR) is 1 MHz at 300 K. Moreover, one finds that the DCR is lower than 1 kHz at 200 K. These results indicate that high-performance InGaAs/Si SPAD can be achieved through a wafer-bonded platform.
Portable 3D-printed umbrella photoacoustic cell for trace gas detection
Authors: Yin Yajie , Niu Mingsheng , Sun Liuya , Tang Min , Chen Jiaxue , Cao Hongzhong 
Published: March 2023

We purpose a novel portable 3D-printed umbrella photoacoustic (PA) cell, to the best of our knowledge, for trace gas detection. Its simulation and structural optimization were performed via finite element analysis using COMSOL software. We investigate the factors affecting the PA signals using both experimentation and theory. By measuring methane, a minimum detection limit of 5.36 ppm (signal-to-noise ratio, 223.8) with a lock-in time of 3s was achieved. The proposed miniature umbrella PA system indicates the potential for a miniaturized and low-cost trace sensor.
Tuberculosis notifications in regional Victoria, Australia: Implications for public health care in a low incidence setting
Authors: Moyo Nompilo , Tay Ee Laine , Trauer James M. , Burke Leona , Jackson Justin , Commons Robert J. , Boyd Sarah C. , Singh Kasha P. , Denholm Justin T. 
Published: March 2023

Background
Regionality is often a significant factor in tuberculosis (TB) management and outcomes worldwide. A wide range of context-specific factors may influence these differences and change over time. We compared TB treatment in regional and metropolitan areas, considering demographic and temporal trends affecting TB diagnosis and outcomes.

Methods
Retrospective analyses of data for patients notified with TB in Victoria, Australia, were conducted. The study outcomes were treatment delays and treatment outcomes. Multivariable Cox proportional hazard model analyses were performed to investigate the effect of regionality in the management of TB. Six hundred and eleven (7%) TB patients were notified in regional and 8,163 (93%) in metropolitan areas between 1995 and 2019. Of the 611 cases in the regional cohort, 401 (66%) were overseas-born. Fifty-one percent of the overseas-born patients in regional Victoria developed TB disease within five years of arrival in Australia. Four cases of multidrug-resistant tuberculosis were reported in regional areas, compared to 97 cases in metropolitan areas. A total of 3,238 patients notified from 2012 to 2019 were included in the survival analysis. The time follow-up for patient delay started at symptom onset date, and the event was the presentation to the healthcare centre. For healthcare system delay, follow-up time began at the presentation to the healthcare centre, and the event was commenced on TB treatment. Cases with extrapulmonary TB in regional areas have a non-significantly longer healthcare system delay than patients in metropolitan (median 64 days versus 54 days, AHR = 0.8, 95% CI 0.6–1.0, P = 0.094).

Conclusion
Tuberculosis in regional Victoria is common among the overseas-born population, and patients with extrapulmonary TB in regional areas experienced a non-significant minor delay in treatment commencement with no apparent detriment to treatment outcomes. Improving access to LTBI management in regional areas may reduce the burden of TB.
Are portable ankle brachial pressure index measurement devices suitable for hypertension screening?
Authors: Janus Justyna , Nicholls Jennifer K. , Pallett Edward , Bown Matthew , Chung Emma M. L. 
Published: March 2023

Objective
In a large-scale population cardiovascular screening programme, peripheral artery disease (PAD) and hypertension would ideally be rapidly assessed using a single device. The ankle-brachial pressure index (ABPI) is calculated by comparing the ankle and brachial blood pressure (BP). However, it is currently unclear whether brachial BP measurements provided by automated PAD screening systems are sufficiently accurate for simultaneous hypertension screening.

Methods
Two portable PAD screening devices, the MESI ABPI MD and Huntleigh’s Dopplex ABIlity, were evaluated following the European Society of Hypertension International Protocol (ESH-IP) Revision 2010 using a mercury-free sphygmomanometer as a reference device.

Results
On average, the MESI slightly underestimated brachial systolic blood pressure (BP) with a bias and standard deviation (SD) of -3.5 (SD: 3.3) mmHg and diastolic BP with a bias of -1.5 (SD: 2.3) mmHg. For systolic BP estimates, the Dopplex was more accurate than the MESI with a lower bias of -0.5 (SD: 4.2) mmHg but less precise. The MESI successfully fulfilled all the requirements of the ESH-IP for hypertension screening. The Dopplex device failed the ESH-IP due to the absence of DBP measurements.

Conclusions
The MESI device appears to be suitable for simultaneous PAD and hypertension screening as part of a preventative care programme. Huntleigh’s Dopplex ABIlity failed to pass the ESH-IP validation test. Further clinical trials are underway to assess the use of the MESI for simultaneous screening for hypertension and PAD in a population screening setting.
La Marina alemana y la evacuación de refugiados en la guerra civil española, 1936-1937
Authors: Gómez García Iñigo 
Published: March 2023

En este artículo se abordará cómo la Marina de guerra alemana participó en la evacuación de miles de extranjeros que buscaban salir de España una vez comenzó la guerra civil. Con base en la documentación primaria alemana, se analizará el despliegue de las fuerzas navales germanas para tratar de entender su modus operandi, poniéndolo en contexto mediante la comparación de sus actividades con las evacuaciones llevadas a cabo por otras marinas en este mismo espacio. Así se mostrará cómo durante el desarrollo de sus operaciones, la Marina alemana favoreció al bando sublevado, tanto por su política de evacuación como por las actividades paralelas que desempeñó durante los primeros meses de la guerra civil.
Para deslocalizar e descolonizar o sistema-mundo moderno
Authors: Cardenal Jozieli , Corona Hieda Maria Pagliosa , Rubin-Oliveira Marlize 
Published: March 2023

Este artigo mobiliza um debate epistêmico voltado a problematizar os cânones paradigmáticos da ciência moderna, propondo um manifesto em prol da pluralidade e da diversidade de saberes. Para tanto, lança a ideia da deslocalização dos saberes, em diálogo com estudos de gênero e teorias feministas decoloniais.
PALAVRAS-CHAVE: Estudos Decoloniais. Sistema-mundo Moderno. Saberes Localizados. Feminismos Decoloniais. Gênero.
Da curandeira à cientista
Authors: Mattos Lyandra de , Baldin Talita 
Published: March 2023

O estudo contextualiza o olhar oferecido à mulher na sociedade como efeito de um certo viés religioso, científico e social. Partindo desta premissa, elaborou-se uma reflexão sobre como a ciência perpetua este status quo e reforça a impossibilidade das mulheres terem acesso à palavra.
PALAVRAS-CHAVE: Ciência. Silenciamento Feminino. Sistema Patriarcal. Psicanálise.
Imperfeitas
Authors: Lopes Ana Luiza Szuchmacher Veríssimo , Vinhas Valéria Quiroga , Silva Marcela Porto de Oliveira 
Published: March 2023

A pesquisa tem como objetivo descrever a percepção sobre a demanda com relação aos papéis de mãe e de profissional de funcionárias durante a pandemia no Rio de Janeiro. Para tal, realizou-se inicialmente uma pesquisa teórica para entender a evolução da mulher dentro do mercado de trabalho, os consequentes impactos sociais gerados e o Mito da Mãe Perfeita.
PALAVRAS-CHAVE: Funcionárias Mães. Pandemia. Maternidade. Pressão.
Domesticidade e maternagem como subversão poético-política
Authors: Guimarães Marta Mencarini 
Published: March 2023

O presente artigo[1] tem como objetivo, estabelecer um diálogo com a produção acadêmica feminista, trafegando por proposições das historiadoras Griselda Pollock na relação entre o sistema de saber-poder baseada no gênero e a construção cultural dos conceitos de feminilidade e domesticidade, bem como, a invisibilidade e o silenciamento de artistas mulheres na história da arte. Serão considerados os apontamentos de Simone de Beauvoir sobre ser e tornar-se mulher e a sexualidade feminina, bem como, a domesticidade como subversão em Luana Tvardovskas e a maternagem como condição política em Bell Hooks e Roberta Barros. A partir da investigação e recorte da produção artística e entrevistas com a artista Clarice Gonçalves, abordamos os conceitos de domesticidade e maternagem como estratégia de subversão na produção artística contemporânea e seus desdobramentos poéticos-políticos.
PALAVRAS-CHAVE: Domesticidade. Maternagem. Arte Contemporânea. Clarice Gonçalves
Simulation and Analysis of Electro Mechanical Actuator with Position Control
Authors: S Rengasamy , D Manamalli , R Ramaprabha 
Published: March 2023

In recent times, Electro-Mechanical Actuator (EMA) is widely employed in various aerospace applications
because of its compactness, ease of maintenance, and cost efficiency. It attracts most of the researcher for simulation and performance analysis. It is very much important to study its control system behaviour. In general, EMA requires, three loop cascade control, but for aerospace application two loop cascade control is used for speed and position controls due to dynamic load changing requirement. Most research efforts on EMA system has used a transfer function model of all its subsystems. Nevertheless, this technique does not yield complete outcomes for analysing its performance. To analyse its performance and characteristics in dynamic condition, an experimental model is essential. In addition, this model needs to cater for analysing performance of different capacity EMA. The primary goal of this work is to simulate unique EMA model with position control using a practical data and analyse its performance. In this design, EMA is modelled by three-phase Brushless Direct Current (BLDC) motor, six-step commutation logic, a speed sensor (Tacho) and a position sensor using Linear Variable Differential Transformer (LVDT). Position and speed controls are handled by Proportional (P) and Proportional plus Integral (PI) controllers respectively. The process reaction curve method is used to tune the controllers. This tuning approach is adequate to enable accurate and robust speed and position control. This paper focus on the simulation and performance analysis of a practical EMA system with position and speed controls in matlab-simulink. The performance analysis results shows that simulated model characteristic is close to physical system and reliable.
Wohnen und soziale Bewegungen
Authors: Tribble Renée 
Published: March 2023

Zusammenfassung
Im Zuge des Protests gegen die Gentrifizierung St. Paulis, und insbesondere aus dem Kampf gegen den Abriss der sog. Esso-Häuser an der Reeperbahn heraus, entstand die PlanBude – ein interdisziplinäres Team, das als GbR für den Beteiligungsprozess zur Neuplanung der Esso-Häuser vom Bezirk Mitte der Freien und Hansestadt Hamburg beauftragt wurde. Die PlanBude steht auch für den aus zwei Containern bestehenden Raum am Ort der Auseinandersetzung. In einem von zugespitzten Konflikten, Verhandlungen und Vereinbarungen geprägten Prozess entstand eine Neuplanung, die nicht zuletzt durch die Arbeit der PlanBude auf dem „Wissen der Vielen“ basiert. Im forschenden Rückblick lassen sich bestimmte Handlungslogiken hoheitlicher Planung und künstlerischer urbaner Praxis finden, die als grundlegend für den Verlauf des Prozesses und die erreichten Ergebnisse gelten können. Zudem wird herausgearbeitet, wie diese in einem relationalen Raumverständnis wirken und wie im Zusammenspiel die Inhalte normativer Planung verändert werden können.
Soziale Bewegungen, die Wohnungsfrage und kritische Theorie – ein Gespräch in Erinnerung an Peter Marcuse
Authors: Güntner Simon , Holm Andrej , Madden David , Mayer Margit , Silver Hilary 
Published: March 2023

ZusammenfassungPeter Marcuse war ein wichtiger Autor in der internationalen kritischen Stadt- und Wohnforschung. Seine Arbeiten, u. a. zu Gentrifizierung und Wohnungspolitik, boten immer wieder Anknüpfungspunkte auch für soziale städtische Bewegungen in New York, Berlin und anderen Städten. Anlässlich seines Todes im März 2022 diskutieren vier renommierte Wissenschaftler:innen über sein Werk und dessen Bedeutung für ihr eigenes Schaffen und für aktuelle Kämpfe für ein Recht auf Stadt und ein Recht auf Wohnen.
Infectious Disease as a Security Threat: A Mental Framework for Future Emergency Preparedness
Authors: Houser Ryan Scott 
Published: March 2023

Abstract
The emergence of COVID-19 pandemic has had significant impacts on human lives as well as economic and social stability. The United States has a complicated history with biosecurity. The September 11th terror attacks uncovered various weaknesses in the national biosecurity infrastructure that have persisted into the current pandemic. This study explores the implications of framing the infectious disease biothreat as a security threat to improve our capabilities while protecting against the potential accelerated threat of bioterrorism in the post-COVID-19 era. To counter the increasing biothreats, the United States must invest in revamping the biodefense infrastructure to increase our resilience to various biothreats.
Connective and magnetic effects in a curved wavy channel with nanoparticles under different waveforms
Authors: Tanveer Anum , Abidin Zain Ul 
Published: March 2023

Abstract
The present study describes the peristaltic flow of Jeffrey fluid with nanomaterial bounded under peristaltic waves in a curved channel. Silver (Ag) is the nanomaterial used for this purpose, and base fluid is water. The diversity of peristaltic waves is captured under four different wave profiles traveling along the curved channel. The consequences of heat generation and mass concentration are also taken. The problem is modeled under physical laws and then simplified using the lubrication technique. The obtained system is sketched in graphs directly using a numerical scheme. The physical outcomes of involved parameters on axial velocity, temperature variation, concentration profile, and streamline patterns are discussed in the last section.
Associations of intimate partner violence and maternal comorbidities: a cross-sectional analysis of the Pregnancy Risk Assessment Monitoring System
Authors: Hartwell Micah , Keener Ashley , Robling Kristyn , Enmeier Mackenzie , Sajjadi Nicholas B. , Greiner Benjamin , Price Jameca 
Published: March 2023

Abstract

Context
Intimate partner violence (IPV) occurs when an intimate partner inflicts physical, sexual, and/or emotional assault with coercive control and is a traumatic experience with repercussions that can be exacerbated when a woman is pregnant. While screening for IPV during pregnancy is recommended to occur regardless of risk, less than 50% of pregnant women are screened.

Objectives
Identifying clinical factors commonly associated with IPV during pregnancy may improve screening rates, thus our primary objective was to examine associations between IPV and maternal comorbidities.

Methods
We conducted a cross-sectional analysis of the Pregnancy Risk Assessment Monitoring System (PRAMS) Phase 8 spanning 2016 through 2019. Bivariate and multivariable logistic regression was utilized to calculate adjusted odds ratios (AORs) to determine associations between IPV and diabetes, anxiety, hypertension, depression, asthma, polycystic ovary syndrome (PCOS), and thyroid disease.

Results
More than 40% of women experiencing IPV reported a history of depression or anxiety. The occurrence of IPV was higher among women with depression (AOR 3.48, CI 3.14–3.85), anxiety (AOR 2.98, CI 2.64–3.37), hypertension (AOR 1.21, CI 1.02–1.44), and asthma (AOR 1.37; CI 1.17–1.59) than women without those respective conditions, but not among diagnoses of diabetes, PCOS, or thyroid disorders.

Conclusions
Our findings show that pregnant individuals reporting having experienced IPV were more likely to report having certain comorbidities compared to those who did not report experiencing IPV. Given the low rates of screening, knowing clinically relevant associations may increase screening sensitivity among clinicians and, in turn, increase the likelihood that individuals experiencing IPV receive supportive care.
Bauhaus und Genossenschaftswesen
Authors: Zepf Uwe 
Published: March 2023

Zusammenfassung
Ausgehend von dem Gemeinschaftsgedanken der Bauschaffenden beim Bauhaus und dem Gemeinschaftsansatz von Wohnungsbaugenossenschaften beim Bauen und Wohnen geht diese Abhandlung den Beziehungen und Wechselwirkungen zwischen Beiden nach. Dabei werden die genossenschaftlichen Aktivitäten und Erfahrungen des zweiten Bauhausdirektors Hannes Meyer bei der Planung und Errichtung des Freidorfes Muttenz dargelegt und bis zu einem Manifest des Bauhauses verfolgt. Mit diesem Rüstzeug werden dann die wechselseitigen Auswirkungen von Bauhaus und Genossenschaftswesen beispielhaft erläutert. Dies erfolgt einerseits anhand der Handwerkergenossenschaftlichen Gildenhall, die von ehemaligen Bauhäuslern mitgetragen wurde und andererseits anhand der Wohnungsbaugenossenschaft Trachau-Nord eG, deren Wohnungsbestand aus den zwanziger und dreißiger Jahren des 20. Jahrhunderts, der architektonischen Haltung des Bauhauses folgend, errichtet wurde.