bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Light‐Programmed Rewritable Lattice‐Mediated Multistate Memory for High‐Density Data Storage
Authors: Sun Qi , Yuan Meili , Wu Rongqi , Miao Yuan , Yuan Yahua , Jing Yumei , Qu Yuanyuan , Liu Xiaochi , Sun Jian 
Published: May 2023

AbstractMainstream non‐volatile memory (NVM) devices based on floating gate structures or phase‐change/ferroelectric materials face inherent limitations that compromise their suitability for long‐term data storage. To address this challenge, a novel memory device based on light‐programmed lattice engineering of thin rhenium disulfide (ReS2 ) flakes is proposed. By inducing sulfur vacancies in the ReS2 channel through light illumination, the device's electrical conductivity is modified accordingly and multiple conductance states for data storage therefore are generated. The device exhibits more than 128 distinct states with linearly increasing conductance, corresponding to a sevenfold increase in storage density. Through further optimization to achieve atomic‐level precision in defect creation, it is possible to achieve even higher storage densities. These states are extremely stable in vacuum or inert ambient showing long retention of >10 years, while they can be erased upon exposure to the air. The ReS2 memory device can maintain its stability over multiple program‐erase operation cycles and shows superior wavelength discrimination capability for incident light in the range of 405–785 nm. This device represents a significant contribution to NVM technology by offering the ability to store information in multistate memory and enabling filter‐free color image recorder applications.
Intrinsic Descriptor Guided Noble Metal Cathode Design for Li‐CO2 Battery
Authors: Guo Chang , Zhang Fuli , Han Xiao , Zhang Lipeng , Hou Qian , Gong Lele , Wang Jincheng , Xia Zhenhai , Hao Jianhua , Xie Keyu 
Published: May 2023

AbstractTo date, the effect of noble metal (NM) electronic structures on CO2 reaction activity remains unknown, and explicit screening criteria are still lacking for designing highly efficient catalysts in CO2‐breathing batteries. Herein, by preferentially considering the decomposition of key intermediate Li2CO3, an intrinsic descriptor constituted of the orbital states and the electronegativity for predicting high‐performance cathode material are discovered. As a demonstration, a series of graphene‐supported noble metals (NM@G) as cathodes are fabricated via a fast laser scribing technique. Consistent with the preliminary prediction, Pd@G exhibits an ultralow overpotential (0.41 V), along with superior cycling performance up to 1400 h. Moreover, the overall thermodynamic reaction pathways on NM@G confirm the reliability of the established intrinsic descriptor. This basic finding of the relationship between the electronic properties of noble metal cathodes and the performance of Li‐CO2 batteries provides a novel avenue for designing remarkably efficient cathode materials for metal‐CO2 batteries.
Transitional Structures with Continuous Variations in Atomic Positions from Anatase to Rutile Improve Photocatalytic Activity
Authors: Song Miao , Prange Micah P. , Ren Peng , Lu Zexi , Lee Jaewon , Zheng Jian , Engelhard Mark , De Yoreo James J. , Sushko Peter V. , Li Dongsheng 
Published: May 2023

AbstractTiO2 polymorphs have distinct properties that are widely employed in various applications. However, mechanisms of transformations between these polymorphs are not fully understood, especially at atomic scale, inhibiting advancing the design and application of the transitional phases. Here, based on results from semi‐in situ transmission electron microscopy, density functional theory, and X‐ray photoemission experiments, a physical picture of transitional structures is discovered, in which continuous variations in atomic positions form along a previously unreported anatase‐to‐rutile phase transformation path of [010]A–to–[]R and (004)A–to– (011)R. These gradient structures give rise to continuous band bending, which promotes electron‐hole separation and inhibits their recombination across the bulk of the particles, leading to a large functionally active volume fraction and resulting in high photoactivity. These findings suggest that interphase matter based on extended gradient structures can be designed to advance new functions not achievable using abrupt interfaces.
Oxygen Assisted Lithium‐Iodine Batteries: Towards Practical Iodine Cathodes and Viable Lithium Metal Protection Strategies
Authors: Giammona Maxwell J. , Kim Jangwoo , Kim Yumi , Medina Phillip , Nguyen Khanh , Bui Holt , Jones Gavin O. , Tek Andy T. , Sundberg Linda , Fong Anthony , La Young‐Hye 
Published: May 2023

AbstractRechargeable batteries with iodine‐based cathodes have recently been the subject of significant interest due to the moderately high theoretical specific energy (≈600 Wh kg−1) and high‐rate capability (>5 C) of the iodine cathode. Progress however has been impeded by the relatively low iodine contents of reported iodine‐based cathodes. This is likely due to high rates of poly‐iodide shuttling and cell instability that takes place at higher cell loadings. To reinforce the lithium metal anode, oxygen gas is introduced in the cells, which leads to a more robust solid‐electrolyte interphase (SEI) layer, improving cell stability. This oxygen‐assisted lithium‐iodine (OALI) battery overcomes many of the shortcomings of other reported lithium‐iodine batteries by utilizing a simple to fabricate lithium iodide (LiI) on activated carbon cathode with cell operating under an oxygen containing atmosphere to realize high‐rate capability (>50 mA cm−2) and high areal capacity (>12 mAh cm−2).
Nano Ultrasound Contrast Agent for Synergistic Chemo‐photothermal Therapy and Enhanced Immunotherapy Against Liver Cancer and Metastasis
Authors: Qiu Yijie , Wu Zhihua , Chen Yanling , Liao Jinghan , Zhang Qi , Wang Quan , Duan Yi , Gong Ke , Chen Sheng , Wang Liting , Fan Peili , Duan Yourong , Wang Wenping , Dong Yi 
Published: May 2023

AbstractAdvanced liver cancer is the most fatal malignant cancer, and the clinical outcomes of treatment are not very satisfactory due to the complexity and heterogeneity of the tumor. Combination therapy can efficiently enhance tumor treatment by stimulating multiple pathways and regulating the tumor immune microenvironment. Nanodrug delivery systems have become attractive candidates for combined strategies for liver cancer treatment. This study reports a nano ultrasound contrast agent (arsenic trioxide (ATO)/PFH NPs@Au‐cRGD) to integrate diagnosis and treatment for efficient ultrasound imaging and liver cancer therapy. This nanodrug delivery system promotes tumor‐associated antigens release through ATO‐induced ferroptosis and photothermal‐induced immunogenic cell death, enhancing the synergistic effects of ATO and photothermal therapy in human Huh7 and mouse Hepa1–6 cells. This drug delivery system successfully activates the antitumor immune response and promotes macrophage M1 polarization in tumor microenvironment with low side effects in subcutaneous and orthotopic liver cancer. Furthermore, tumor metastasis is inhibited and long‐term immunological memory is also established in orthotopic liver cancer when the nanodrug delivery system is combined with anti‐programmed death‐ligand 1 (PD‐L1) immunotherapy. This safe nanodrug delivery system can enhance antitumor therapy, inhibit lung metastasis, and achieve visual assessment of therapeutic efficacy, providing substantial potential in clinic applications for liver cancer.
Chemical Profiles of the Oxides on Tantalum in State of the Art Superconducting Circuits
Authors: McLellan Russell A. , Dutta Aveek , Zhou Chenyu , Jia Yichen , Weiland Conan , Gui Xin , Place Alexander P. M. , Crowley Kevin D. , Le Xuan Hoang , Madhavan Trisha , Gang Youqi , Baker Lukas , Head Ashley R. , Waluyo Iradwikanari , Li Ruoshui , Kisslinger Kim , Hunt Adrian , Jarrige Ignace , Lyon Stephen A. , Barbour Andi M. , Cava Robert J. , Houck Andrew A. , Hulbert Steven L. , Liu Mingzhao , Walter Andrew L. , de Leon Nathalie P. 
Published: May 2023

AbstractOver the past decades, superconducting qubits have emerged as one of the leading hardware platforms for realizing a quantum processor. Consequently, researchers have made significant effort to understand the loss channels that limit the coherence times of superconducting qubits. A major source of loss has been attributed to two level systems that are present at the material interfaces. It is recently shown that replacing the metal in the capacitor of a transmon with tantalum yields record relaxation and coherence times for superconducting qubits, motivating a detailed study of the tantalum surface. In this work, the chemical profile of the surface of tantalum films grown on c‐plane sapphire using variable energy X‐ray photoelectron spectroscopy (VEXPS) is studied. The different oxidation states of tantalum that are present in the native oxide resulting from exposure to air are identified, and their distribution through the depth of the film is measured. Furthermore, it is shown how the volume and depth distribution of these tantalum oxidation states can be altered by various chemical treatments. Correlating these measurements with detailed measurements of quantum devices may elucidate the underlying microscopic sources of loss.
Coexistence of Ferroelectricity and Ferromagnetism in Fullerene‐Based One‐Dimensional Chains
Authors: Zhao Yang , Guo Yu , Qi Yan , Jiang Xue , Su Yan , Zhao Jijun 
Published: May 2023

AbstractOne‐dimensional (1D) magnetoelectric multiferroics are promising multifunctional materials for miniaturized sensors, actuators, and memories. However, 1D materials with both ferroelectricity and ferromagnetism are quite rare. Herein, using first‐principles calculations, a series of fullerene‐based 1D chains, namely U2C@C80‐M (M = Cr, Mn, Mo, and Ru) 1D chains with both ferroelectric (FE) and ferromagnetic (FM) properties is designed. Compared to individual U2C@Ih(7)‐C80, the spontaneous polarization (Ps) in 1D chains is enhanced by about two to four times owing to the interaction between U2C@Ih(7)‐C80 fullerene and M (M = Cr, Mn, Mo, and Ru) atoms. Meanwhile, the introduction of transition metal atoms dopes electrons into U's 5f orbitals, leading to numerous intriguing magnetic properties, such as U2C@C80‐Cr and U2C@C80‐Mo as 1D ferromagnetic semiconductors, U2C@C80‐Ru as 1D ferrimagnetic (FiM) semiconductor, and U2C@C80‐Mn as 1D antiferromagnetic (AFM) semiconductor. Excitingly, it is found that magnetic ordering and electrical polarization can be modulated independently by linking different transition metal atoms. These findings not only broaden the range of 1D multiferroic materials, but also provide promising candidates for novel electronic and spintronic applications.
CRISPR Assays for Disease Diagnosis: Progress to and Barriers Remaining for Clinical Applications
Authors: Huang Zhen , Lyon Christopher J. , Wang Jin , Lu Shuihua , Hu Tony Y. 
Published: May 2023

AbstractNumerous groups have employed the special properties of CRISPR/Cas systems to develop platforms that have broad potential applications for sensitive and specific detection of nucleic acid (NA) targets. However, few of these approaches have progressed to commercial or clinical applications. This review summarizes the properties of known CRISPR/Cas systems and their applications, challenges associated with the development of such assays, and opportunities to improve their performance or address unmet assay needs using nano‐/micro‐technology platforms. These include rapid and efficient sample preparation, integrated single‐tube, amplification‐free, quantifiable, multiplex, and non‐NA assays. Finally, this review discusses the current outlook for such assays, including remaining barriers for clinical or point‐of‐care applications and their commercial development.
Cathode Materials and Chemistries for Magnesium Batteries: Challenges and Opportunities
Authors: Li Zhenyou , Häcker Joachim , Fichtner Maximilian , Zhao‐Karger Zhirong 
Published: May 2023

AbstractRechargeable magnesium batteries hold promise for providing high energy density, material sustainability, and safety features, attracting increasing research interest as post‐lithium batteries. With the progressive development of Mg electrolytes with enhanced (electro‐)chemical stability, tremendous efforts have been devoted to the exploration of high‐energy cathode materials. In this review, recent findings related to Mg cathode chemistry are summarized, focusing on the strategies that promote Mg2+ diffusion by targeting its interaction with the cathode hosts. The critical role of the cathode–electrolyte interfaces is elaborated, which remains largely unexplored in Mg systems. The approaches to optimization of cathode–electrolyte combinations to unlock the kinetic limitations of Mg2+ diffusion, enabling fast electrochemical processes of the cathodes, are highlighted. Furthermore, representative conversion chemistries and coordination chemistries that bypass bulk Mg2+ diffusion are discussed, with particular attention given to their key challenges and prospects. Finally, the hybrid systems that combine the fast kinetics of the monovalent cathode chemistries and high‐capacity Mg anodes are revisited, calling for further practical evaluation of this promising strategy. All in all, the aim is to provide fundamental insights into the cathode chemistry, which promotes the material development and interfacial regulations toward practical high‐performance Mg batteries.
Radical‐Mediated Photocatalysis for Lignocellulosic Biomass Conversion into Value‐Added Chemicals and Hydrogen: Facts, Opportunities and Challenges
Authors: Aboagye Dominic , Djellabi Ridha , Medina Francesc , Contreras Sandra 
Published: May 2023

AbstractPhotocatalytic biomass conversion into high‐value chemicals and fuels is considered one of the hottest ongoing research and industrial topics toward sustainable development. In short, this process can cleave Cβ−O/Cα−Cβ bonds in lignin to aromatic platform chemicals, and further conversion of the polysaccharides to other platform chemicals and H2. From the chemistry point of view, the optimization of the unique cooperative interplay of radical oxidation species (which are activated via molecular oxygen species, ROSs) and substrate‐derived radical intermediates by appropriate control of their type and/or yield is key to the selective production of desired products. Technically, several challenges have been raised that face successful real‐world applications. This review aims to discuss the recently reported mechanistic pathways toward selective biomass conversion through the optimization of ROSs behavior and materials/system design. On top of that, through a SWOT analysis, we critically discussed this technology from both chemistry and technological viewpoints to help the scientists and engineers bridge the gap between lab‐scale and large‐scale production.
Doubly Strapped Zwitterionic NIR‐I and NIR‐II Heptamethine Cyanine Dyes for Bioconjugation and Fluorescence Imaging
Authors: Li Dong‐Hao , Gamage Rananjaya S. , Oliver Allen G. , Patel Nimit L. , Muhammad Usama Syed , Kalen Joseph D. , Schnermann Martin J. , Smith Bradley D. 
Published: May 2023

AbstractHeptamethine cyanine dyes enable deep tissue fluorescence imaging in the near infrared (NIR) window. Small molecule conjugates of the benchmark dye ZW800‐1 have been tested in humans. However, long‐term imaging protocols using ZW800‐1 conjugates are limited by their instability, primarily because the chemically labile C4′‐O‐aryl linker is susceptible to cleavage by biological nucleophiles. Here, we report a modular synthetic method that produces novel doubly strapped zwitterionic heptamethine cyanine dyes, including a structural analogue of ZW800‐1, with greatly enhanced dye stability. NIR‐I and NIR‐II versions of these doubly strapped dyes can be conjugated to proteins, including monoclonal antibodies, without causing undesired fluorophore degradation or dye stacking on the protein surface. The fluorescent antibody conjugates show excellent tumor‐targeting specificity in a xenograft mouse tumor model. The enhanced stability provided by doubly strapped molecular design will enable new classes of in vivo NIR fluorescence imaging experiments with possible translation to humans.
Light Triggered Pore Size Tuning in Photoswitching Covalent Triazine Frameworks for Low Energy CO2 Capture
Authors: Huang Qi , Zhan Zhen , Sun Ruixue , Mu Junju , Tan Bien , Wu Chunfei 
Published: May 2023

AbstractRecently, photo switching porous materials have been widely reported for low energy costed CO2 capture and release via simply remoted light controlling method. However, most reported photo responsive CO2 adsorbents relied on metal organic framework (MOFs) functionalisation with photochromic moieties, and MOF adsorbents still suffered from chemically and thermally unstable issues. Thus, further metal free and highly stable organic photoresponsive adsorbents are necessary to be developed. CTFs, because of their high porosity and stability, have attracted great attention for CO2 capture. Considering the high CO2 uptake capacity and structural tunability of CTFs, it suggests high potential to fabricate the photoswitching CTF materials by the same functionalisation method as MOFs. Herein, the first series of photo switching CTFs were developed for low energy CO2 capture and release. Apart from that, the CO2 switching efficiency could be doubled either through the azobenzene numbers adjusting method or through the previously reported structural alleviation strategy. Furthermore, the pore size distribution of azobenzene functionalised PCTFs also could be tuned under UV exposure, which may contribute to the UV light induced decrease of CO2 uptake capacity. These photoswitching CTFs represented a new kind of porous polymers for low energy costed CO2 capture.
Constructing a honeycomb‐inspired Ni‐Co LDHs@CFs enhanced polymer composites with high strength, aging resistance and excellent anti‐wear for tribological applications
Authors: Zhu Wenting , Zhang Shouyang , Fei Jie , Li Chang , Yang Hongtao , Liu Longqi 
Published: May 2023

AbstractThe development of carbon fibers/polymer composites (CFPCs) has made a profound impact on varied application prospects in the transmission and braking fields, where interface engineering between fibers/matrix holds the key to co‐enhanced mechanical and tribological properties. Herein, we designed a honeycomb‐inspired Ni‐Co layered double hydroxides (Ni‐Co LDHs) modified CFPCs, in which Ni‐Co LDHs interconnected nanosheets were grown in‐situ onto the carbon fibers (CFs) surface via the oxidation‐assisted hydrothermal method, and then polymer matrix fully impregnate and filled with both the CFs and LDHs porous containers by capillary forces. Benefiting from the special interface, the Ni‐Co LDHs grafted CFs reinforced polymer composites (Ni‐Co LDHs@CFs composites) possessed the excellent mechanical strength and outstanding tribological properties. The LDHs@CFs composites had 32% improvement in the tensile strength, and 84.9% strength retention ratio after the hydrothermal aging process. Furthermore, the friction coefficient was increased by 24% and wear rate was dramatically decreased by 42% from 6.148 × 10−14 to 3.557 × 10−14 m3 (N m)−1, indicating better torque transmitting capacity and anti‐wear properties. This work could provide a valuable reference for the construction of biomimetic interface to simultaneously improve the mechanical and tribological properties of the CFPCs.
Characterization of a Musculoskeletal Syndrome of Enthesitis and Arthritis in Patients With Atopic Dermatitis Treated With Dupilumab, an Interleukin‐4/13 Inhibitor
Authors: Hughes Catherine D. , Nathan Joseph , Mathew Libin , Pink Andrew E. , Woolf Richard T. , Smith Catherine , Menon Bina , Kirkham Bruce 
Published: May 2023

ObjectiveTo characterize the presentation and outcomes of patients with atopic dermatitis (AD) who developed musculoskeletal symptoms after treatment with dupilumab, a human IgG4 monoclonal antibody that blocks the functions of interleukin‐4 (IL‐4) and IL‐13, key pathologic pathways in AD.MethodsThis article reports an observational cohort of patients receiving dupilumab who developed new‐onset musculoskeletal symptoms after dupilumab therapy at our center. All patients had a comprehensive rheumatologic history and examination, with imaging by ultrasonography (US) or magnetic resonance imaging (MRI) in most patients.ResultsBetween October 2018 and February 2021, we recorded 470 patients with AD commencing dupilumab treatment from routine clinical care records. Of 36 patients referred for rheumatologic assessment, we identified 26 patients (14 male, 12 female) with a musculoskeletal syndrome of inflammatory enthesitis, arthritis, and/or tenosynovitis. Clinical findings were confirmed by US and MRI. All patients had very good response to dupilumab treatment, and no specific predictors of musculoskeletal syndrome were noted. Symptoms were mild in 16 patients, moderate in 6 patients, and severe in 4 patients. Receipt of nonsteroidal antiinflammatory drugs or cyclooxygenase 2 inhibitors, reduction of dupilumab dose/frequency, and cessation of dupilumab therapy led to improvement, but moderate or severe symptoms persisted for many months.ConclusionWe report a new musculoskeletal syndrome of inflammatory enthesitis/arthritis/tenosynovitis in some patients receiving the IL‐4 receptor antagonist dupilumab. This response to a cytokine‐targeting therapy provides key insights into the pathogenesis of enthesitis.
White Light to Near‐IR Chargeable Single Component Photocapacitor Based on Donor‐chromophore‐Acceptor Dyes
Authors: Li Feng , Cuhadar Can , Zhang Zilong , Jindal Shanay , Huang Zehan , Zhang Ni , Tsao Hoi Nok , Gao Peng 
Published: May 2023

AbstractPower sources that can be charged anytime and anywhere are highly desirable for mobile devices. The most suitable device for achieving such wireless charging is a photocapacitor, which utilizes light as a renewable energy source instead of electricity from the grid. Sunlight on Earth is intermittent and unstable, so photocapacitors that can be charged by the day or room light and near‐infrared (near‐IR) radiation are needed to ensure the uninterrupted operation of the equipment. We employ a single dye‐sensitized solar cell as a photocapacitor without adding any additional charge storage components to reduce the cost and complexity of device manufacturing. To realize such photocapacitors, this work presents a family of new isoindigo‐based D‐π‐A photoactive dyes with good visible and near‐IR absorption. Notably, LF15 has a higher molar absorbance coefficient and enhanced dye‐loading than LF23, which is consistent with the higher photocurrent of photocapacitors based on the former. Photocapacitors based on these three dyes achieve photovoltages up to 0.74 V, area‐specific capacitances of 2.87 mF cm−2, and excellent charge‐discharge stability. The devices can be charged in both visible and near‐IR conditions, exhibiting typical capacitor behavior.