bluuebunny/crossref_metadata_2025_split huggingface dataset:
Conjunctival malignant melanoma in a horse
Authors: Moore Cecil P. , Collins B. Keith , Linton Lana L. , Collier Linda L. 
Published: August 2023

AbstractA case of malignant melanoma originating from the conjunctiva of a horse is reported. The tumor exhibited locally aggressive behavior as evidenced clinically by recurrence following two treatment episodes including surgical excision on each occasion and one application of cryotherapy. The orbit was subsequently exenterated and histologically malignant conjunctival melanoma was confirmed. Histopathologic features included variable pigmentation with amelanotic sites demonstrating marked cellular and nuclear pleomorphism with high numbers of mitotic figures. Cords of neoplastic cells invaded the sclera and cornea. Following exenteration, the horse exhibited no recurrence of the tumor for five years before being lost to follow‐up. To our knowledge, this is the first report of primary malignant conjunctival melanoma in a horse.
Corneal stromal sequestration and keratoconjunctivitis sicca in a horse
Authors: McLellan Gillian J. , Archer F. Joy 
Published: August 2023

AbstractA 19‐year‐old Shetland pony presented with unilateral ocular discomfort and abnormal ocular appearance. Keratoconjunctivitis sicca, ulcerative keratitis and brown discoloration of the corneal stroma were identified on ophthalmic examination. The etiology of keratoconjunctivitis sicca was not determined in this case. For practical and financial reasons, the owners requested enucleation of the affected eye. Histopathologic examination revealed extensive loss of corneal epithelium overlying a zone of hypereosinophilic, degenerate, and necrotic corneal stroma. This well‐circumscribed region of corneal stromal sequestration was surrounded by stromal vascularization, and an intense inflammatory, predominantly polymorphonuclear, cellular infiltrate. The clinical and histopathologic features of this case were considered remarkably similar to those observed in feline corneal stromal sequestration.
Fabrication and verification of a single aligned nanofibre gas sensor based on non‐contact direct writing method
Authors: Zadeh Sadegh Pouriyan , Nikfarjam Alireza , Mohammadi Alireza Salavati 
Published: August 2023

AbstractIn this letter, the non‐contact direct writing method for producing single aligned fibre utilizing polyvinylpyrrolidone (PVP) polymer has been explored. It has been shown that with the help of this method, nanofibres can be created in a controlled manner with designed structures. This form of nanofibres is being studied with the goal of using it in carbon monoxide (CO) gas sensors. The temperature required for the annealing operation was 500°C, and finally the authors obtained nanofibres with diameter of 200 nm. In addition, a simulation technique built on the Monte Carlo method has also been introduced. It is shown that this simulation method is compatible with the experimental results with reasonable accuracy. The results showed that the authors have a correlation of about 0.934 between experimental results obtained in 30 ppb of CO gas and its simulation data.
An adaptive decision‐making approach for transmission expansion planning considering risk assessment of renewable energy extreme scenarios
Authors: Zhao Pengfei , Xu Xinzhi , Dong Xiaochong , Gao Yi , Sun Yingyun 
Published: August 2023

AbstractThe extreme power output scenarios of renewable energy sources (RES) proposed new challenges to the safe and stable operation of the power system. Transmission expansion planning (TEP) with large‐scale RES grid integration needs considering the risk of extreme scenarios. In this paper, an adaptive decision‐making approach for the TEP problem based on planning‐risk assessment‐replanning iterative process is proposed. The method obtains massive temporal and spatial correlated wind‐photovoltaic (PV) power output scenarios by generalizing the historical data to describe the uncertainties. A data‐driven load loss risk assessment model (RAM) based on the power system's actual operating state is built, referring to the degree of extreme scenario risks on the balance of supply and demand, and the probability of extreme scenario occurrence. The planning decision is progressively revised according to the risk assessment result. The Garver's 6‐bus system and the IEEE RTS 24‐bus system are adopted as simulation cases. The results show that the optimal expansion plans achieve a balance between the economy and robustness, which verifies the effectiveness of the proposed method.
The miniJPAS survey
Authors: Maturi M. , Finoguenov A. , Lopes P. A. A. , González Delgado R. M. , Dupke R. A. , Cypriano E. S. , Carrasco E. R. , Diego J. M. , Penna-Lima M. , Doubrawa L. , Vílchez J. M. , Moscardini L. , Marra V. , Bonoli S. , Rodríguez-Martín J. E. , Zitrin A. , Márquez I. , Hernán-Caballero A. , Jiménez-Teja Y. , Abramo R. , Alcaniz J. , Benitez N. , Carneiro S. , Cenarro J. , Cristóbal-Hornillos D. , Ederoclite A. , López-Sanjuan C. , Marín-Franch A. , Mendes de Oliveira C. , Moles M. , Sodré Jr L. , Taylor K. , Varela J. , Vázquez Ramió H. , Fernández-Ontiveros J. A. 
Published: August 2023

Context. Samples of galaxy clusters allow us to better understand the physics at play in galaxy formation and to constrain cosmological models once the mass, position (for clustering studies), and redshift are known. In this context, large optical datasets play a crucial role.
Aims. We investigate the capabilities of the Javalambre-Physics of the Accelerating Universe Astrophysical Survey (J-PAS) in detecting and characterizing galaxy groups and clusters. We analysed the data of the miniJPAS survey, obtained with the JPAS-Pathfinder camera and covering 1 deg2 centred on the AEGIS field to the same depths and with the same 54 narrow-band filters plus two broader-band near-UV and near-IR filters anticipated for the full J-PAS survey.
Methods. We used the Adaptive Matched Identifier of Clustered Objects (AMICO) algorithm to detect and characterize groups and clusters of galaxies down to S/N = 2.5 in the redshift range 0.05 < z < 0.8.
Results. We detected 80, 30, and 11 systems with signal-to-noise ratios higher than 2.5, 3.0, and 3.5, respectively, down to ∼1013 M⊙ h−1. We derive mass-proxy scaling relations based on Chandra and XMM-Newton X-ray data for the signal amplitude returned by AMICO, the intrinsic richness, and a new proxy that incorporates the galaxies’ stellar masses. This proxy is made possible thanks to the J-PAS filters and shows a smaller scatter with respect to the richness. We fully characterize the sample and use AMICO to derive a probabilistic membership association of galaxies with the detected groups that we test against spectroscopy. We further show how the narrow-band filters of J-PAS provide a gain of up to 100% in signal-to-noise ratio in detection and an uncertainty on the redshift of clusters of only σz = 0.0037(1 + z), placing J-PAS between broad-band photometric and spectroscopic surveys.
Conclusions. The performance of AMICO and J-PAS with respect to mass sensitivity, mass-proxies quality, and redshift accuracy will allow us to derive cosmological constraints not only based on cluster counts, but also based on clustering of galaxy clusters.
The main evolutionary pathways of massive hierarchical triple stars
Authors: Kummer F. , Toonen S. , de Koter A. 
Published: August 2023

Context. So far, stellar population studies have mainly focused on the evolution of single and binary stars. Recent observations show that triple and higher order multiple star systems are ubiquitous in the local population, especially among massive stars. Introducing three-body dynamical effects can influence the evolution of an individual stellar system and can therefore affect the predicted rates of astrophysical sources that are a product of stellar evolution. Therefore, predictions of triple star evolution are necessary for a more complete understanding of the evolutionary behaviour of stellar populations and their end products.
Aims. We aim to constrain the main evolutionary pathways of massive hierarchical triple star systems and to quantify the effect of the third star on the evolution of the system.
Methods. We model the massive triple star population by performing simulations of triple star evolution with the TRES code, which combines stellar evolution with secular evolution of triple systems, and explore how robust the predictions of these simulations are under variations of uncertain initial conditions. We focus on coeval, hierarchical stellar triples in pre-mass-transfer phases.
Results. Interactions are common among massive triple stars. The majority of systems (65%–77%) experience a phase of mass transfer in the inner binary, often with a main sequence donor star. This differs significantly from isolated binary evolution, where mass transfer is less frequent (52.3% instead of 67% for our fiducial model) and the donors are typically post-main sequence stars. Initial constraints for dynamical stability as well as eccentricity oscillations driven by the third body facilitate the occurrence of interactions, such as mass transfer. The requirement of dynamical stability at formation places quite stringent constraints on allowed orbital properties, reducing uncertainties in triple evolution that resort from these initial conditions. Ignoring three-body dynamics during evolution of non-interacting triples leads to triple compact-object systems with stronger eccentricity oscillations and thereby likely over-predicts the merger rate of compact objects in such systems.
Die neuralgische Amyotrophie: eine häufige Ursache uni- oder bilateraler Zwerchfellparesen
Authors: Zimmermann Maximilian , Wollsching-Strobel Maximilian , Majorski Daniel Sebastian , Kroppen Doreen , Schwarz Sarah Bettina , Berger Melanie , Windisch Wolfram , Holle Johannes Fabian 
Published: August 2023

ZusammenfassungEine ein- oder beidseitige Zwerchfellparese kann verschiedene Ursachen haben, an erster Stelle stehen (intraoperative) Verletzungen des Nervus phrenicus. In bis zu 20% der Fälle lässt sich jedoch trotz umfangreicher Abklärung keine Erklärung finden. Die neuralgische Amyotrophie (NA, syn. Parsonage-Turner-Syndrom) ist eine häufige, im Alltag unterdiagnostizierte, multifokale autoimmun-inflammatorische Erkrankung, die überwiegend proximale Nervenabschnitte der oberen Extremitäten betrifft. Klassische Symptome sind akut einsetzende, starke Schmerzen im Bereich des Schultergürtels mit zeitverzögert auftretenden Paresen der Schulter- und Armmuskulatur. In mindestens 7% der Fälle ist der N. phrenicus (mit-)betroffen. Legt man die jährliche Inzidenz einer NA von 1:1000 zugrunde, ist die Entität als Ursache einer Zwerchfellfunktionsstörung wahrscheinlich nicht so ungewöhnlich, wie bislang angenommen. Die klinische Erfahrung zeigt jedoch, dass diese Diagnose oft nicht in Betracht gezogen und die Zwerchfellparese somit fälschlicherweise als idiopathisch klassifiziert wird. Fatal ist dies v.a. im Hinblick auf die Möglichkeit einer medikamentösen Therapie mittels Kortikosteroiden im Akutstadium einer NA sowie einer möglicherweise zu frühen operativen Zwerchfellraffung aufgrund des Potenzials der Erkrankung einer spontanen Heilung auch viele Monate nach Symptombeginn.Ziel des vorliegenden Artikels ist es, das Bewusstsein für die Entität der NA als Ursache einer Zwerchfellparese zu schärfen und einen standardisierten Ansatz für die Diagnostik und Behandlung zu etablieren.
Comparison of Transcutaneous and Total Serum Bilirubin Measurements
at Five Different Sites in Newborns before and after
Phototherapy
Authors: Eken Seda , Ilhan Ozkan , Hakan Nilay 
Published: August 2023

Abstract
Objective This study aims to examine the accuracy of transcutaneous
bilirubin (TcB) in estimating the total serum bilirubin (TSB) level at five
different sites before and immediately after phototherapy.
Methods This study prospectively enrolled infants with a gestational age
of 34 to 416/7 weeks who were clinically diagnosed with
neonatal jaundice and required phototherapy within 28 days after birth. TcB
levels were measured on the uncovered four areas (forehead, mid-sternum,
abdomen, and interscapular site) and covered hipbone by using the Dräger
JM-103 Jaundice Meter before phototherapy and at 0 min after
discontinuing phototherapy. Correlation and agreement between TcB and TSB levels
were assessed before and after phototherapy.
Results We included 108 infants with a mean gestational age of
37.6±1.5 weeks and birth weight of 3108±548 g. A strong
significant correlation was found between TSB and TcB measurements at all five
sites before phototherapy with the strongest correlation at the interscapular
site (r=0.768, p=0.001). The correlation was weakened between
TSB and TcB at all five sites after phototherapy; however, the strongest
correlation was at the covered hipbone (r=0.619, p=0.001). TcB
measurements at all five sites tended to underestimate TSB levels before and
after phototherapy. The difference (TcB − TSB) tended to increase with
increasing TSB levels.
Conclusions TcB levels were most accurately measured at the interscapular
site and covered hipbone before and immediately after phototherapy,
respectively.
Effect of Perioperative Prophylactic Intravenous Antibiotic Use in Immediate Implant-Based Breast Reconstruction: A Retrospective Matched Cohort Study
Authors: In Seok Kyung , Park Seok Won , Myung Yujin 
Published: August 2023

Abstract
Background Among breast reconstruction methods, implant-based breast reconstruction has become the mainstream. However, periprosthetic infection is still an unresolved problem. Although published articles have revealed that limited use of antibiotics is sufficient to reduce infection rates, the number of surgeons still preferring elongated usage of antibiotics is not less. The aim of our study is to validate the appropriate duration of antibiotic use to reduce infection rate after implant-based breast reconstruction.
Methods A retrospective study reviewed medical record of 235 patients (274 implants for reconstruction) who underwent prepectoral direct to implant breast reconstruction using acellular dermal matrix wrapping technique. Infection rates were analyzed for the patients administered postoperative prophylactic antibiotics until drain removal and those who received only perioperative prophylactic antibiotics for 24 hours.
Results Of the 274 implants, 98 who were administered prophylactic antibiotics until drain removal had an infection rate of 3.06% (three implants) and 176 who received prophylactic antibiotics no longer than 24 hours postoperatively had an infection rate of 4.49% (eight implants). A total of 11 patients diagnosed with postoperative infection clinically, 8 were salvaged by antibiotic treatment, and 3 had implant removal and replacement with autologous flap. Postoperative antibiotic prophylaxis duration had no statistically significant effects in the risk of infection (p = 0.549).
Conclusion The duration of prophylactic antibiotics after surgery was not related to infection risk. Further study with a large number of patients, randomized control study, and route of antibiotics is needed.
Perioperative Neonatal Acute Kidney Injury Is Common: Risk Factors for Poor Outcomes
Authors: Mohamed Tahagod H. , Mpody Christian , Nafiu Olubukola 
Published: August 2023

Objective Perioperative acute kidney injury (AKI) is associated with poor patient outcomes. The epidemiology of perioperative AKI is characterized in children and to a lesser extent in neonates with cardiac disease. We hypothesized that the prevalence of noncardiac perioperative AKI in neonates is higher than in older children. We also hypothesized that certain neonatal characteristics and comorbidities increase the risk of perioperative AKI and hospital mortality. We aimed to characterize the epidemiology and risk factors of perioperative AKI in neonates undergoing noncardiac surgeries and outline the associated mortality risk factors.
Study Design We performed a retrospective study of neonates ≤28 days old who underwent inpatient noncardiac surgery in 46 U.S. children's hospitals participating in the Pediatric Hospital Information System between 2016 and 2021. AKI was evaluated throughout the surgical admission encounter. AKI was defined using the International Classification of Diseases (ICD) versions 9 and 10 codes. Comorbid risk factors are chronic and longstanding diagnoses and were selected using ICD-9 and ICD-10 diagnostic and procedure codes.
Results Perioperative AKI occurred in 10% of neonates undergoing noncardiac surgeries. Comorbidities associated with high risk of perioperative AKI included metabolic, hematologic/immunologic, cardiovascular, and renal disorders. The relative risk of mortality in perioperative AKI was highest in infants with low birthweight (relative risk = 1.49, 1.14–1.94) and those with hematologic (1.46, 1.12–1.90), renal (1.24, 1.01–1.52), and respiratory comorbidities (1.35, 1.09–1.67).
Conclusion Perioperative AKI is common in neonates undergoing noncardiac surgeries. Infants with high-risk comorbidity profiles for the development of perioperative AKI and mortality may benefit from close surveillance of their kidney function in the perioperative period. Although retrospective, the findings of our study could inform clinicians to tailor neonatal perioperative kidney care to improve short- and long-term outcomes.
Key Points
A Primary Intraosseous Meningioma: A Rare Case of Malignancy with High Proliferative Ability
Authors: Sato Yoshiki , Mitsuya Koichi , Kakuda Yuko , Oishi Takuma , Deguchi Shoichi , Sugino Takashi , Akiyama Yasuto , Nagashima Takeshi , Urakami Kenichi , Shimoda Yuji , Ohshima Keiichi , Hayashi Nakamasa , Yamaguchi Ken 
Published: August 2023

AbstractPrimary intraosseous meningioma (PIM) is a rare tumor that arises in the skull. Histopathologically, it is generally described as a slow-growing, benign lesion. However, on rare occasions, PIM presents as a malignancy with high proliferative ability, which requires maximal resection, adjuvant radiotherapy, and subsequent careful follow-up. Because of the rarity of such cases, they present a diagnostic challenge with unusual pathological findings. Herein, we report a case of a primary intraosseous anaplastic meningioma with extensive invasion inside and outside the skull, along with the results of whole-genome analysis. Histopathological diagnosis was a World Health Organization grade 3 anaplastic meningioma. In the literature, only two cases of anaplastic PIM have been reported, so its characteristics and treatment are poorly understood. Our patient was successfully treated with tumor resection, followed by intensity-modulated radiation therapy. Follow-up imaging studies revealed no recurrence or distant metastasis, including to lung, liver, and bone, at 8 months after the surgery.
Redox-Tag-Guided Radical Cation Diels–Alder Reactions: Use of Enol Ethers as Dienophiles
Authors: Okada Yohei , Morizumi Haruka , Nakayama Kaii , Kitano Yoshikazu 
Published: August 2023

AbstractAlthough radical cation Diels–Alder reactions enable the formation of cyclohexene ring systems between electronically mismatched (both electron-rich) dienes and dienophiles, which is otherwise difficult or impossible to achieve under thermal conditions, the substrate scope has been limited. Herein, we disclose that a radical cation Diels–Alder reaction using an enol ether as an electron-rich (and therefore oxidizable) dienophile is possible through a rationally designed redox tag strategy. Electrochemical and TiO2 photochemical approaches are effective in driving the reaction, where both intermolecular and intramolecular electron transfers are the key.
The effects of the healthcare line in a stroke unit: three years' experience of a center in the Northeast of Brazil
Authors: Rangel Deborah Moreira , Feitosa Anna Karuza Nogueira , Araújo Flaviane Melo , Pinheiro Mara Cibelly da Silva , Cidrão Alan Alves de Lima 
Published: August 2023

Abstract
Background Treatment at an organized stroke unit center (SUC) improves survival after stroke. Stroke mortality has decreased worldwide in recent decades.
Objective This study shows the experience of a SUC in the Northeast of Brazil, comparing its first, second, and third years.
Methods We compared data on the SUC prospectively collected from 31 July 2018 to 31 July 2019 (year 1), August 1st, 2019, to July 31st, 2020 (year 2), and August 1st to July 31st, 2021 (year 3).
Results There was an expertise evolution through the years, with good outcomes in spite of the coronavirus disease 2019 pandemic in the 3rd year. Also, in the 1st year, the median (interquartile range) door-to-needle time was 39.5 (29.5–60.8) minutes evolving to 22 (17–30) minutes, and then to 17 (14–22) minutes in the last year.
Conclusion This was the first report on a SUC's outcome in the Brazil's Central Arid Northeast countryside, and it shows the improvement in care for patients with stroke through an effective healthcare line.
New role of astrocytes in neuroprotective mechanisms after ischemic stroke
Authors: Xie Xiaoyun , Liu Jingli 
Published: August 2023

AbstractAstrocytes are the most abundant cell subtypes in the central nervous system. Previous studies believed that astrocytes are supporting cells in the brain, which only provide nutrients for neurons. However, recent studies have found that astrocytes have more crucial and complex functions in the brain, such as neurogenesis, phagocytosis, and ischemic tolerance. After an ischemic stroke, the activated astrocytes can exert neuroprotective or neurotoxic effects through a variety of pathways. In this review, we will discuss the neuroprotective mechanisms of astrocytes in cerebral ischemia, and mainly focus on reactive astrocytosis or glial scar, neurogenesis, phagocytosis, and cerebral ischemic tolerance, for providing new strategies for the clinical treatment of stroke.
A Pilot Single-Site Randomized Control Trial: Investigating the Use of Donor Milk in Late Preterm and Term Infants in the Neonatal Intensive Care Unit
Authors: Pithia Neema , Grogan Tristan , Garg Meena , Kesavan Kalpashri , Calkins Kara L. 
Published: August 2023

Objective We aimed to study donor milk (DM) supplementation when mother's own milk (MOM) was unavailable in term and late preterm infants (LPIs) admitted to the neonatal intensive care unit (NICU). We hypothesized that this study would be feasible, defined by the rate of consent, diet adherence, and study completion. We further hypothesized that compared with formula supplementation, DM supplementation, for no longer than 7 days from birth, would be associated with an increase in breastfeeding attempts and the percentage of MOM (MOM%) without adversely affecting growth. Breastfeeding attempts and MOM% were assessed over 48 hours at the end of the intervention, which was defined as NICU discharge or at the end of supplementation, whichever came sooner.
Study Design This was a pilot study (n = 32). Infants with a gestational age > 34 weeks admitted to the NICU were included. Infants were randomized to one of two groups: human milk (MOM + DM) or formula (MOM + F).
Results The consent rate was 52%. Adherence to the study diet was 97%, and completion was 100%. When the MOM + DM group was compared with the MOM + F group, there was no difference in breastfeeding attempts (median [interquartile range]: 3.5 [1.5–6] vs. 1.5 [0.5–4] times, p = 0.1) or MOM% (60 vs. 59%, p = 0.9). Weight and length at multiple time points were similar when the groups were compared.
Conclusion A study randomizing term and LPIs in the NICU to DM or formula when MOM was unavailable is feasible. It remains unclear if DM improves breastfeeding success in this population.
Key Points