bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lessons From the Edge
Authors: Barrett-Carrier Lynne 
Published: April 2023

When schools across this province were ordered to close on March 13, 2020, due to the Covid-19 pandemic, classroom teachers could never have imagined the profound repercussions of this decision and the colossal impact this would have on both teachers and students across Quebec. Teachers scrambled to upgrade their technology skills as school boards quickly mobilized to provide much-needed technical support and hardware for teachers, students, and parents/guardians. More than ever, home and school needed to be connected. In a quick response to the urgent need to provide a continued opportunity for learning, the virtual classroom soon took centre stage.
In January 2022, a couple of months before the pandemic sent us into lockdown, I became a McGill Field Supervisor for the Faculty of Education as my career as a secondary school/ adult education ELA teacher would soon come to a close. I had planned to retire that June after teaching for 42 years at the English Montreal School Board. In my three final months at the EMSB, I designed, with a colleague, an online Secondary 5 ELA course, and became very well-acquainted with Microsoft Teams and all it had to offer. The course was both solid and engaging, affording the students the opportunity to work on their own, in small groups in break out rooms, and co-operatively as a whole class. Students were expected to participate and were held accountable for their contributions to the learning experience.
La gestion de classe
Authors: Moukaddam Dunia 
Published: April 2023

Composer avec l’inédit, saisir l’imprévu, créer du renouveau, la gestion de classe dans son évolution semble se déterminer par la capacité de gérer le quotidien en le réinventant au rythme du renouveau et des relations. Est-ce le mot « équilibre » qui en détient le mot de passe pour que le quotidien, porteur de rituels et de sécurité, soit aussi porteur de découvertes, d’apprentissages, d’émerveillements et de transformations ? Ou est-ce le mot « engagement » qui permet à l’enseignant de prendre des initiatives et de veiller au développement professionnel autonome pour affermir une posture qui lui permet de s’ouvrir et d’ouvrir sans cesse de nouveaux horizons ?
Le défi de l’heure en enseignement
Authors: Bissonnette Steve , Gauthier Clermont 
Published: April 2023

Le contexte pandémique a exacerbé les difficultés comportementales des élèves. À ce sujet, l’Institut National de Santé Publique du Québec (INSPQ, 2021) a montré des effets négatifs de la pandémie sur le développement des enfants de 2 à 12 ans. L’INSPQ (2021) a recensé 14 études, provenant de divers pays, ayant examiné le domaine du développement social et affectif, principalement en ce qui concerne les problèmes de comportements internalisés et externalisés. Dans ces études, les problèmes de comportements internalisés réfèrent aux difficultés émotionnelles comme la dépression, l’anxiété, etc. Les comportements externalisés sont associés aux problèmes de conduite, à l’irritabilité et la mauvaise humeur, à l’hyperactivité/l’inattention, aux problèmes relationnels avec les pairs, à la manifestation d’agressivité ou à un trouble de l’opposition. L’INSPQ (2021) indique « [qu’] une majorité d’études rapportent une augmentation significative des problèmes de comportements internalisés et externalisés, comparativement à la période prépandémique, » (p. 5).
La formation
Authors: Rolando Delphine 
Published: April 2023

19 h, le téléphone sonne, on me demande d’animer un cours demain à 9h. Heureusement, j’ai déjà animé ce cours récemment. Je recherche mes notes, mon ordinateur, mon support PowerPoint. Mince ! Impossible de remettre la main dessus. Ça y est, je l’ai retrouvé ! plus qu’à préparer ma tenue chic, mais confortable pour entrer sur scène (l’amphithéâtre de la faculté) et tout sera prêt pour le lendemain !
Argumenter sur l’argumentation : regards croisés sur les apports de la transdisciplinarité en recherche
Authors: Lalancette Mireille , Caty Marie-Ève , Drolet Marie-Josée 
Published: April 2023

Dans le cadre de cet article, nous utilisons notre expérience de recherche et de rédaction de l’ABC de l’argumentation pour les professionnels de la santé ou toute autre personne qui veut convaincre (publié aux Presses de l’Université du Québec) comme un tremplin pour réfléchir à notre collaboration interdisciplinaire et transdisciplinaire. Nous présentons la manière dont nous avons collaboré au fil des ans ainsi que la façon dont nos regards différents, mais complémentaires, sur un même objet – l’argumentation – ont permis (1) d’offrir une perspective riche et diversifiée sur cet objet de recherche, (2) d’alimenter des discussions épistémologiques et éthiques, (3) de bonifier nos regards respectifs et (4) de développer une collaboration féconde. Ces réflexions nous permettront de revenir plus largement, et de manière plus théorique, sur notre approche de la transdisciplinarité, laquelle nous apparaît pertinente pour aborder divers enjeux sociaux contemporains, liés à nos disciplines respectives et à ceux relatifs à l’intersectionnalité.
Poor air quality is associated with impaired visual cognition in the first two years of life: A longitudinal investigation
Authors: Spencer John P , Forbes Samuel H , Naylor Sophie , Singh Vinay P , Jackson Kiara , Deoni Sean , Tiwari Madhuri , Kumar Aarti 
Published: April 2023

Background:Poor air quality has been linked to cognitive deficits in children, but this relationship has not been examined in the first year of life when brain growth is at its peak.Methods:We measured in-home air quality focusing on particulate matter with diameter of <2.5 μm (PM2.5) and infants’ cognition longitudinally in a sample of families from rural India.Results:Air quality was poorer in homes that used solid cooking materials. Infants from homes with poorer air quality showed lower visual working memory scores at 6 and 9 months of age and slower visual processing speed from 6 to 21 months when controlling for family socio-economic status.Conclusions:Thus, poor air quality is associated with impaired visual cognition in the first two years of life, consistent with animal studies of early brain development. We demonstrate for the first time an association between air quality and cognition in the first year of life using direct measures of in-home air quality and looking-based measures of cognition. Because indoor air quality was linked to cooking materials in the home, our findings suggest that efforts to reduce cooking emissions should be a key target for intervention.Funding:Bill & Melinda Gates Foundation grant OPP1164153.
Homoeopathic rare remedies for osteoarthritis of knee joint
Authors: Khan Sadaf 
Published: April 2023

The 2 nd most common rheumatological problem and most frequent joint disease is osteoarthritis. The prevalence of osteoarthritis in India ranges from 22% to 39%. OA is more common in females than males and its prevalence increases with advanced age. As per the literature available osteoarthritis of the knee joint is mostly seen in the population. Various complementary and alternative therapy is open to the patients to choose the best for themselves. There are side effects seen with NSAID’s thus patients are moving towards modalities in CAM. The homeopathic system of medicine has remedies that are already proven on human beings having no side effects to the patients, yet are effective. Homoeopathy offers a great chance for patients suffering from the pain, stiffness and limitation in daily activities. This particular article is listed with a few rare homoeopathic remedies indicated in homoeopathic materia medica for osteoarthritis like Angustura vera, ArgemoneMexicana, Formica rufa, Jacaranda Caroba, Osteoarthritic Nosode, Salicylic acid, Slag.
Emerging diseases in Australian oysters and the challenges of climate change and uncertain futures
Authors: Scanes Elliot , O’Connor Wayne A. , Seymour Justin R. , Siboni Nachshon , Parker Laura M. , Ross Pauline M. 
Published: April 2023

ABSTRACT
Oysters are a valuable and iconic seafood, deeply rooted in Australian culture. However, oysters have always been vulnerable to disease, with disease outbreaks leading to mass mortality events that regularly cost the oyster aquaculture industry millions of dollars and affect livelihoods. Notably, there is evidence that climate change is rapidly causing the emergence of new diseases alongside the amplification of impacts of existing diseases. This is because warming, acidification and freshening of coastal and estuarine habitats is affecting the three axes of disease; the host, the external environment and the pathogens. Here we explore how climate change is likely to impact all three axes of disease in Australian oyster aquaculture. Climate change is affecting oyster physiology, leading to weaker immune defences that allow for increased susceptibility to viral and bacterial infections. For example, there is evidence that recent heavy rain events precede oyster disease in estuaries. In addition, climate change is increasing the abundance and virulence of bacterial and viral pathogens, potentially resulting in the introduction of novel disease into new habitats. In order to remain viable, we suggest that the Australian oyster industry needs to enhance selective breeding programs currently underway with a diversification of products and research on emerging diseases to ensure resilience in the sector.
Determination of Recent In-Migrants in Yogyakarta using Bayesian Regression Logistics
Authors: Rohmah Devi Azarina Manzilir , Astuti Ani Budi , Efendi Achmad 
Published: April 2023

Aims: This research aims to find out the status determinant of recent in-migrants entering the province of Yogyakarta, Indonesia in 2021 with Bayesian logistic regression combined with a nonlinear principal component analysis in the process of forming a latent variable.
Study Design: Quantitative Design.
Place and Duration of Study: This research was carried out in the city of Yogyakarta with the data used is 1 year data throughout 2021.
Methodology: The data were obtained from the results of national socio-economic surveys (SUSENAS) KOR in March 2021.
Results: The research results indicate that particular variables such as age, resident latest education, the status of main activities, the status of residential ownership, housing quality, and asset ownership have significant influences on recent in-migrants entering the Province of Yogyakarta, Indonesia.
Conclusion: This research concludes that the Bayesian approach in logistic regression with iteration 1,000,000, 4 thinning interval, and 500.000 burn-in indicates that of seven variables, six variables with significant influences on the status of recent migrants entering the Province of Yogyakarta consist of age (X1), latest education (X3), main activities (X4), house ownership (X5), housing quality (X6), and asset ownership (X7). Of these six variables, the younger resident, the resident with high school or equal as their latest education, the resident currently working as their main activity, the resident renting a house, and the resident with high housing quality score and high asset ownership score are more likely to do recent migration to the Province of Yogyakarta.
Social Vulnerability and Risk of Suicide in US Adults, 2016-2020
Authors: Liu Shuhan , Morin Samuel B. , Bourand Natalie M. , DeClue Isabella L. , Delgado Gustavo E. , Fan Jiahe , Foster Sabrina K. , Imam Maaz S. , Johnston Coulter B. , Joseph Franklin B. , Lu Yihao , Sehrawat Ujjwal , Su Li Chun , Tavan Ketaki , Zhang Kelly L. , Zhang Xingruo , Saulsberry Loren , Gibbons Robert D. 
Published: April 2023

ImportanceThere were over 45 000 suicides in the US in 2020, making suicide the 12th leading cause of death. If social vulnerability is associated with suicide rates, targeted interventions for at-risk segments of the population may reduce US suicide rates.ObjectiveTo determine the association between social vulnerability and suicide in adults.Design, Setting, and ParticipantsThis cohort study analyzed 2 county-level social vulnerability measures (the Social Vulnerability Index [SVI] and the Social Vulnerability Metric [SVM]) and US Centers for Disease Control and Prevention–reported county-level suicides from 2016 to 2020. Data were analyzed November and December 2022.ExposuresCounty-level variability in social vulnerability.Main Outcomes and MeasuresThe primary outcome measure was number of county-level adult suicides from 2016 to 2020, offset by county adult population during those years. The association between social vulnerability (measured using the SVI and the newly created SVM for 2018) and suicide was modeled using a bayesian-censored Poisson regression model to account for the CDC’s suppression of county-level suicide counts of less than 10, adjusted for age, racial and ethnic minority, and urban-rural county characteristics.ResultsFrom 2016 to 2020, there were a total of 222 018 suicides in 3141 counties. Comparing the least socially vulnerable (0% to 10%) to the most socially vulnerable (90% to 100%) counties, there was a 56% increase in suicide rate (17.3 per 100 000 persons to 27.0 per 100 000 persons) as measured by the SVI (incidence rate ratio, 1.56; 95% credible interval, 1.51-1.60) and an 82% increase in suicide rate (13.8 per 100 000 persons to 25.1 per 100 000 persons) as measured by the SVM (incidence rate ratio, 1.82; 95% credible interval, 1.72-1.92).Conclusions and RelevanceThis cohort study found that social vulnerability had a direct association with risk for adult suicide. Reducing social vulnerability may lead to life-saving reduction in the rate of suicide.
Long COVID—Challenges in diagnosis and managing return-to-work
Authors: Tan Kian Wei Alvin , Koh David 
Published: April 2023

Abstract

Objectives
Long COVID may be a public health concern resulting in a hidden toll of the pandemic years later, on workers and their work ability in the workforce. We illustrate the challenges in diagnosing long COVID in a patient, its associated psychological impact on work and how return-to-work can be better managed and supported from an occupational health perspective.

Methods
An Occupational Health trainee working as a government public health officer experienced persistent fatigue, decreased effort tolerance, and difficulties in concentration after contracting COVID-19. There were unintended psychological effects arising from the functional limitations that were not explained with a proper diagnosis. This was further complicated with a lack of access to occupational health services for return-to-work.

Results
He developed his own rehabilitation plan to improve his physical tolerance. Progressive efforts to build up his physical fitness complemented with workplace adjustments helped to overcome his functional limitations and allowed him to effectively return-to-work.

Conclusion
Diagnosing long COVID continues to remain challenging due to a lack of consensus on a definitive diagnostic criterion. This may give rise to unintended mental and psychological impact. Workers with long COVID symptoms can return-to-work, involving a complex individualized approach to the symptoms’ impact on work, and workplace adjustments and job modifications available. The psychological toll on the worker must also be addressed. Occupational health professionals are best placed to facilitate these workers in their journey to return-to-work, with multi-disciplinary delivery models providing return to work services.
Effects of apolipoprotein E polymorphism on cerebral oxygen saturation, cerebral perfusion, and early prognosis after traumatic brain injury
Authors: Lin Xun , Li Qilin , Sun Xiaochuan , Shi Quanhong , Dan Wei , Zhan Yan , Deng Bo , Xia Yulong , Xie Yanfeng , Jiang Li 
Published: April 2023

AbstractObjectiveTo investigate the effects of the apolipoprotein E (APOE) gene on oxygen saturation and cerebral perfusion in the early stages of traumatic brain injury (TBI).MethodsThis study included 136 consecutive TBI patients and 51 healthy individuals. The APOE genotypes of all subjects were determined using quantitative fluorescence polymerase chain reaction (QF‐PCR). Regional cerebral oxygen saturation (rScO2) of patients with TBI and normal subjects was monitored using near‐infrared spectroscopy (NIRS). Computed tomography (CT) perfusion was used to obtain cerebral perfusion in patients with TBI and normal subjects.ResultsIn the TBI group, the rScO2 of APOEε4 carriers (53.06 ± 6.87%) was significantly lower than that of non‐carriers (58.19 ± 5.83%, p < 0.05). Meanwhile, the MTT of APOEε4 carriers (6.75 ± 1.30 s) was significantly longer than that of non‐carriers (5.87 ± 1.00 s, p < 0.05). Furthermore, correlation analysis showed a negative correlation between rSCO2 and MTT in patients with TBI. Both the univariate and multifactorial logistic regression analyses revealed that APOE ε4, hypoxia, MTT >5.75 s, Marshall CT Class, and GCS were independent risk factors for early poor prognosis in patients with TBI.ConclusionBoth cerebral perfusion and cerebral oxygen were significantly impaired after TBI, and low cerebral perfusion and hypoxia were related to poor prognosis of patients with TBI. Compared with APOE ε4 non‐carriers, APOE ε4 carriers not only had poorer cerebral perfusion and cerebral oxygen metabolism but also worse prognosis in the early stages of TBI. Furthermore, a negative correlation was observed between the rSCO2 and MTT levels. In addition, both CT perfusion scanning (CTP) and NIRS are reliable for monitoring the condition of patients with TBI in the neurological intensive care unit (NICU).
Finite‐time composite control for fuzzy delayed semi‐Markovian jump systems with multiple disturbances and uncertainty
Authors: Xu Tianbo , Zhu Chunxia , Qi Wenhai , Cao Jinde , Cheng Jun , Shi Kaibo , Pan Guangsheng 
Published: April 2023

SummaryThis article is concerned with the issue of finite‐time analysis for fuzzy semi‐Markovian jump systems (S‐MJSs) with multiple disturbances. Takagi–Sugeno fuzzy method is applied to address the nonlinear problem of closed‐loop systems. Unlike the existing research, delay, multiple disturbances, generally uncertain transition rate, uncertain parameters are all analyzed in a unify S‐MJSs framework. The aim of this study is to construct a composite control strategy for stable operation of S‐MJSs with multiple disturbances on the basis of the actual system requirements. For S‐MJSs, conservatism of analysis method and uncertainty of actual system are both the significant problems need to be solved urgently. First, the sufficient condition of S‐MJSs is obtained to guarantee the finite‐time stable performance through mathematical analysis and matrix inequality derivation. Second, disturbance observer based control and control are combined to deal with the effects of multiple disturbances which contain incomplete information disturbance and norm bounded disturbance. Third, fuzzy controller is designed to satisfy close‐loop systems finite‐time performance. Finally, the actual nonlinear example is presented to verify the accuracy of the approach.
Pathogenesis‐Guided Engineering of Multi‐Bioactive Hydrogel Co‐Delivering Inflammation‐Resolving Nanotherapy and Pro‐Osteogenic Protein for Bone Regeneration
Authors: Liu Shan , Wang Wenle , Wu Peng , Chen Zhiyu , Pu Wendan , Li Lanlan , Li Gang , Zhang Jianxiang , Song Jinlin 
Published: April 2023

AbstractThere are still great challenges in promoting bone defect repair via regeneration strategies. In view of delayed bone healing due to local inflammation, herein, pathogenesis‐guided engineering of multi‐bioactive hydrogel therapy is proposed for bone regeneration, by simultaneously improving the osteoimmune environment and enhancing osteogenic differentiation of stem cells. After discovering the pivotal role of persistent inflammation and bone loss in the pathogenesis of periodontitis by transcriptomics, a multi‐bioactive nanotherapy based on self‐assembled nanomicelles (PP5 NMs) is first developed. PP5 NMs effectively rescue osteogenesis of human periodontal ligament cells under pathological conditions and promote bone formation in rats with mandibular or cranial bone defects. By integrating PP5 NMs, a pro‐osteogenic protein rhBMP9, and a hydrogel‐forming temperature‐responsive material, a multifunctional hydrogel therapy is further engineered, which can regulate the pro‐inflammatory/oxidative microenvironment and accelerate bone regeneration. The obtained multi‐bioactive hydrogel capable of co‐delivering and sustainedly releasing PP5 NMs and rhBMP9 displays excellent bone regeneration capability, by synergistic effects of inflammation‐resolving and pro‐osteogenic differentiation of stem cells. Mechanistically, this hydrogel therapy improves the osteoimmune environment by attenuating pathogenesis and enhancing stem cell differentiation via the TLR4/NF‐κB/HO‐1 axis and activating the Smad1/5/8 protein complex. The hydrogel is promising for treating different inflammatory bone diseases.
Guiding Fibroblast Activation Using an RGD‐Mutated Heparin Binding II Fragment of Fibronectin for Gingival Titanium Integration
Authors: Heras‐Parets Aina , Ginebra Maria‐Pau , Manero Jose Maria , Guillem‐Marti Jordi 
Published: April 2023

AbstractThe formation of a biological seal around the neck of titanium (Ti) implants is critical for ensuring integration at the gingival site and for preventing bacterial colonization that may lead to periimplantitis. This process is guided by activated fibroblasts, named myofibroblasts, which secrete extracellular matrix (ECM) proteins and ECM‐degrading enzymes resolving the wound. However, in some cases, Ti is not able to attract and activate fibroblasts to a sufficient extent, which may compromise the success of the implant. Fibronectin (FN) is an ECM component found in wounds that is able to guide soft tissue healing through the adhesion of cells and attraction of growth factors (GFs). However, clinical use of FN functionalized Ti implants is problematic because FN is difficult to obtain, and is sensitive to degradation. Herein, functionalizing Ti with a modified recombinant heparin binding II (HBII) domain of FN, mutated to include an Arg‐Gly‐Asp (RGD) sequence for promoting both fibroblast adhesion and GF attraction, is aimed at. The HBII‐RGD domain is able to stimulate fibroblast adhesion, spreading, proliferation, migration, and activation to a greater extent than the native HBII, reaching values closer to those of full‐length FN suggesting that it might induce the formation of a biological sealing.