bluuebunny/crossref_metadata_2025_split huggingface dataset:
Training items for trainee residents in community medicine in rural areas
Authors: Kumabe Ayako , Kenzaka Tsuneaki , Goda Ken , Yahata Shinsuke 
Published: June 2023

Abstract
Objective
To examine the significant events experienced by initial trainees during community medicine training, evaluate their impact on community medicine practice, and support improvements in rural community medicine training.
Results
Three faculty teachers independently evaluated significant event analysis reports from 25 trainee residents who had completed four weeks of community medicine training in a rural area. Reports were analyzed according to topics relating to rural community medicine derived from the Model Core Curriculum for Medical Education. The most frequently reported items were identified as follows: Primary care: 9 (36.0%); integrated community care systems: 8 (32.0%); medical care in the local community: 7 (28.0%); home health care and systems, patient–physician relationship, and end-of-life medical treatment and care: 6 each (24.0%). Reports from residents describing events related to home health care and systems and end-of-life medical treatment and care related to more than one item.
Do Inequalities of Opportunity Influence Access to Financial Products in Cameroon? An Analysis Using the Shapley and Oaxaca-Blinder Decompositions
Authors: ONDOA Henri ATANGANA , TCHINDA Arnold Dilane MOMOU 
Published: June 2023

Abstract
The aim of this study is to analyze the influence of inequalities of opportunity in access to financial products in Cameroon. Based on the Finscope 2017 survey data, we use the "IOP" command to estimate inequalities of opportunity. Furthermore, we decompose the total inequality of opportunity obtained with the Shapley and Oaxaca-Blinder methods. We find that inequalities of opportunity are most pronounced in the possession of a formal bank account and the access to credit from a formal financial institution. However, their influence is relatively smaller for formal savings account and mobile money account ownership. The decomposition methods show that the circumstantial factors that contribute most to inequality of opportunity in access to financial products are parental education, the individual's place of residence and the social capital. Circumstances such as gender and age, contribute on average very little to the opportunity gaps observed in access to financial products in Cameroon.
JEL classification: D63, D140, G21.
Oxidation and cross-linking to improve stability and sizing properties of cassava starch with ammonium persulfate-assisted hexamethylenetetramine
Authors: Wang Miao , Qian Dechen , Wu Hailiang , Zhao Yahao , Shen Yanqin , Yao Yijun 
Published: June 2023

Abstract
An oxidation cross-linking modified cassava starch (AHS) with high thermal viscosity stability and good film-forming property was synthesized by oxidation cross-linking and amidation reaction，which used ammonium persulfate (APS) as the oxidant, hexamethylenetetramine (HMT) as the cross-linking agent and urea as an assistant. The results of Fourier transform infrared spectroscopy (FTIR) and nuclear magnetic resonance (1H NMR) showed that compared with cassava starch, the strength of the hydroxyl peak on the AHS structure changed, and the strength of the intramolecular hydrogen bond decreased. The crosslinking agent HMT releases formaldehyde under heating conditions to crosslink oxidized starch. The auxiliary urea undergoes an amidation reaction to form amide bonds while adsorbing residual formaldehyde, improving the toughness of the AHS sizing film. When the APS usage is 0.4% (carboxyl content is 0.3024%), the HMT usage is 0.35% (sedimentation volume is 7.8mL), and urea usage exceeds 3%, the viscosity thermal stability of the AHS sizing agent is well (97.12%), and the elongation of the sizing film can reach 2.97%. Finally, The AHS sizing agent can improve the tensile properties and wear resistance of cotton yarn. This study overcomes the toxic substance emissions caused by traditional aldehyde crosslinking agents, improves the viscosity stability of the starch sizing agent, and provides a new approach to improving the viscosity thermal stability and film-forming properties of starch sizing agents.
Multi-vesicular Liposome and its Applications: A Novel Chemically Modified
Approach for Drug Delivery Application
Authors: Ghosal Kajal , Pani Ayan , Chowdhury Totan , Kundu Abhijeet , Thomas Sabu 
Published: June 2023

Background:
This study aimed to elaborate on all the aspects of multivesicular liposomes,
including structure, function, topology, etc. Liposomes are a unique drug delivery system, in which
both hydrophilic and hydrophobic drug molecules can be incorporated. Particularly, multivesicular
liposomes have more advantages than other liposomes because of their unique structure. This study
provides an overview of several works already performed by various researchers in this field. Numerous
studies have reported on preparing and evaluating multivesicular liposomes for drug delivery applications.
This study summarizes the process of formulating multivesicular liposomes and their application
in drug delivery systems and provides details about how to resolve the problem of limited
solubility and stability of biomolecules, along with controlled drug release kinetics, with the possibility
of loading various drugs. There is no doubt that multivesicular liposome opens new avenues to
develop novel drug delivery system for achieving the desired functional performances and expanding
the applications in the drug delivery area.
Possibilities and Challenges of Delivering Health-Related Small Group Interventions Online: Scoping Review
Authors: Preuhs Katharina , Klein Velderman Mariska , van Empelen Pepijn 
Published: June 2023

Background
The outbreak of the COVID-19 pandemic required the transition of health-related face-to-face group interventions to an online setting. While it seems that group outcomes can be realized in an online setting, less is known about resulting potential challenges (and advantages) and how these can be overcome.

Objective
The aim of this article is to explore what challenges and advantages may arise when providing health-related small group interventions in an online setting and how to overcome these challenges.

Methods
Scopus and Google Scholar databases were searched for relevant literature. Effect studies, meta-analyses, literature reviews, theoretical frameworks, and research reports relating to synchronous, face-to-face, health-related small group interventions, online group interventions, and video teleconferencing group interventions were identified and screened. Findings relating to potential challenges and corresponding strategies are described. In addition, potential advantages of online group settings were explored. Relevant insights were gathered until saturation of results relating to the research questions was reached.

Results
The literature indicated several aspects that require extra attention and preparation in the online group setting. These include the delivery of nonverbal communication and affect regulation, as well as the build-up of group cohesion and therapeutic alliance, which seem more challenging online. Yet there are strategies to overcome these challenges, such as metacommunication, collecting participant feedback, and providing guidance concerning technical accessibility. In addition, the online setting provides opportunities to reinforce group identity, such as by allowing independence and the ability to create homogeneous groups.

Conclusions
While online, health-related small group interventions offer a considerable number of possibilities and benefits compared to face-to-face groups, there are also potential drawbacks to consider, which, if anticipated, can be to a great extent overcome.
Tổng hợp vật liệu Zn-ZIF có độ kết tinh cao trong dung môi nước ở nhiệt độ phòng định hướng xúc tác phân hủy chất thải ô nhiễm 4-nitrophenol
Authors: Diệp Lê Hà Thơ , Nguyễn Bùi Thị Quế Trân , Huỳnh Thái , Nguyễn Phú Quí , Nguyễn Thị Tuyết Nhung 
Published: June 2023

Vật liệu khung cơ kim cấu trúc zeolite dựa trên cluster tứ diện ZnN4 được tổng hợp trong dung môi nước, ở nhiệt độ phòng. Phản ứng được khảo sát với nguồn muối kẽm ZnSO47H2O kết hợp với linker 2‑methylimidazole (2‑HmIm) ở những điều kiện khác nhau về nồng độ của 2‑HmIm và tỉ lệ mol 2‑HmIm/Zn. Cấu trúc của vật liệu được xác định bằng phương pháp nhiễu xạ tia X (PXRD). Hình thái của mẫu được quan sát bằng kính hiển vi điện tử quét (SEM) và thành phần nguyên tố được phân tích bằng phổ tán xạ năng lượng tia X (EDS). Độ bền nhiệt của vật liệu được xác định qua phân tích nhiệt trọng lượng (TGA). Kết quả cho thấy vật liệu Zn-ZIF được tổng hợp thành công theo quy trình hóa học xanh với độ kết tinh cao và độ bền nhiệt lớn. Sản phẩm được tiếp tục sử dụng làm xúc tác phản ứng khử 4‑nitrophenol với chất khử NaBH4. Nghiên cứu sơ bộ cho thấy Zn-ZIF chưa biến tính không thể hiện hoạt tính xúc tác do các vị trí ZnN4 đã hoàn toàn bão hòa. Kết quả nghiên cứu này mở ra định hướng biến tính vật liệu tạo các tâm kim loại chưa bão hòa được bố trí phân tán trên khung sườn carbon.
The Addition of Copper Nanoparticles to Mineral Trioxide Aggregate for Improving the Physical and Antibacterial Properties
Authors: Fakhriza Muhammad Akram , Rusdiarso Bambang , Sunarintyas Siti , Nuryono Nuryono 
Published: June 2023

The physical and antibacterial properties of mineral trioxide aggregate (MTA) have been improved by adding copper nanoparticles (CuNP). The CuNP colloid was synthesized by reacting CuCl2·2H2O and NaBH4 as the reducing agent using C6H8O6 as the capping agent. The Cu(II) concentration was varied by 3.0, 6.0, and 9.0 mM to produce CuNP-3, CuNP-6, and CuNP-9 colloids, respectively. The CuNP colloids were characterized with a UV-Vis spectrophotometer and TEM. MTA was hydrated with CuNP at a mass-to-volume ratio of 2:1 to produce Cu-MTA-3, Cu-MTA-6, and Cu-MTA-9, respectively. All products were characterized with XRD and SEM-EDX. The compressive strength, pH, Ca ion release, and solubility were measured, and antibacterial activity was tested. The results showed a spherical shape of the synthesized CuNP with a particle size of ~28.08 nm. Adding CuNP-9 to hydrated MTA increased the compressive strength, pH, Ca ion release, and solubility, with the value of 4.78±0.38 MPa; 9.01±0.03; 1718±63 ppm, and 22.48±0.37%, respectively. The highest antibacterial activity occurred for Cu-MTA-9, with an inhibition zone of 10.15±0.47 mm against S. aureus and 11.93±1.16 mm against P. aeruginosa. The findings show a potential application of the product for endodontic materials containing antibacterial agents.
O EIXO ESTATÍSTICA NOS ANOS INICIAIS DO ENSINO FUNDAMENTAL: PERSPECTIVAS A PARTIR DA PEDAGOGIA HISTÓRICO-CRÍTICA
Authors: Da Silva Araújo Adriana Jerônimo , Nozella Gama Carolina 
Published: June 2023

Este artigo é resultado da nossa pesquisa de mestrado que analisou o eixo estatística na coleção do livro didático Buriti Mais Matemática (2017) para os anos iniciais do Ensino Fundamental. Apresentamos neste momento um recorte da dissertação, visando discutir as contribuições do ensino de estatística nos anos iniciais do Ensino Fundamental, a partir da concepção pedagógica histórica-crítica.O trabalho bibliográfico valeu-se dos estudos de Cazorla et al. (2017); CAZORLA (2002); CAZORLA e CASTRO (2008); ORSO (2021); GALVÃO, LAVOURA, MARTINS (2019); GIARDINETTO (2012); CASCAVEL (2008), etc. Concluímos que o ensino de estatística não deve estar restrito a fórmulas matemáticas e a níveis de leitura, mas, deve contribuir para a transformação social. Nessa perspectiva, é preciso superar a ideia de que não é qualquer conteúdo que fará com que o estudante se desenvolva nas suas máximas possibilidades, pois só os conhecimentos ricos em oportunidades de desenvolvimento podem de alguma maneira ampliar a formação do indivíduo em sua forma mais elaborada.
INFÂNCIA BRASILEIRA: OLHARES PARA A VIOLÊNCIA DURANTE A PANDEMIA
Authors: Batomarco Nobre Lara , Voltarelli Monique Aparecida 
Published: June 2023

O presente trabalho desenvolve-se a partir de uma pesquisa guarda-chuva, sobre infância e pandemia, realizada a partir do Programa Institucional de Bolsas de Iniciação Científica (PIBIC) da Universidade de Brasília no período de 2022 a 2023. Como recorte de um estudo mais amplo, esta pesquisa visa, a partir das produções científicas, a exploração dos aspectos relacionados à infância vivenciada durante a pandemia da Covid-19, com efeito nas circunstâncias que corroboraram para a intensificação da violência infantil no território brasileiro durante o período de isolamento social, tendo em vista que a quarentena fortaleceu os fenômenos propulsores de diversos tipos de violência, que compõem uma temática de extrema urgência. Desta forma, investiga-se neste artigo as variadas características das violências praticadas contra as crianças, bem como as consequências e efeitos resultantes de agressões psicológicas, físicas, sexuais, de maus tratos, do rompimento dos direitos infantis e até da violência mediada pelas tecnologias digitais a partir das publicações acadêmicas deste período.
LA ENSEÑANZA MUSICAL EN LA FORMACIÓN DE DOCENTES PARA LAS PRIMERAS INFANCIAS
Authors: Zilli Lía Rosa 
Published: June 2023

El presente trabajo expone y socializa algunas dimensiones posibles de abordarse desde la Educación Musical en la formación de docentes de Educación Inicial.
La discusión y la reflexión sobre diversas instancias vivenciales en la formación superior se estructuran en torno al desarrollo de juegos musicales y de ficción, de estímulos concordantes, de enfoque multimodal de obras musicales y de algunos aportes desde la pedagogía que discute la noción de destino -que refiere a una pérdida de singularidad que se posa sobre las infancias- cuando se trata de pensar políticas educativas y formación de las mismas. A partir de allí, este trabajo instaura un plural de posibilidades que situadas desde la enseñanza musical se pueden ofrecer a quienes trabajan junto a ellas.
Se proponen algunas dimensiones de análisis que a partir de la musicalidad comunicativa, del enfoque de la cognición musical temprana y la teoría de la cognición corporeizada posibilitan en las prácticas musicales junto a las infancias: la escucha, el disfrute, la experimentación y la producción-contextualización de diferentes manifestaciones artísticas en la Educación Inicial.
ENSEÑANZA DE LA LITERATURA EN EL PRIMER CICLO DEL NIVEL INICIAL, TRADICIONES, SABERES Y PRÁCTICAS DOCENTES EN JARDINES DE LA CIUDAD DE SANTA FE (ARGENTINA)
Authors: Paniccia Adriana 
Published: June 2023

Este trabajo de investigación constituye una invitación a conocer cómo se configuran las propuestas de enseñanza de la literatura de los docentes en el primer ciclo del nivel inicial, cuáles son las tradiciones que las sustentan y los saberes que se ponen en juego durante el diseño y puesta en práctica de las mismas.
Dicha investigación se llevó a cabo durante el período 2020 se tomó como muestra un total de veinte instituciones del Nivel Inicial de la Ciudad de Santa Fe, que cuentan con un mínimo de dos secciones Primer Ciclo.
El diseño metodológico de estudio de caso consideró las siguientes etapas de investigación cualitativa, elaboración de las encuestas y realización de entrevistas semiestructuradas a las docentes del nivel inicial.
Esto permitió un acercamiento a conocer las prácticas de literatura que realizan las docentes en las salas y a los obstáculos que se presentan en la concreción de las mismas requiriendo por parte del docente reflexionar acerca del sentido que sustentan sus decisiones cotidianas y tener en cuenta conocimientos que permitan abordar a la literatura como un discurso literario, para mejorar las prácticas educativas.

Palabras clave: enseñanza, literatura, nivel inicial, prácticas docentes
O GARIMPO ILEGAL E A SAÚDE DOS IANOMÂMIS
Authors: Teixeira Cunha Wéltima 
Published: June 2023

O mercúrio é um metal mais estudado em razão da sua utilização e consequências danosas aos humanos e ao ecossistema. Esse fato se deve aos efeitos tóxicos para a saúde humana e contaminação ambiental, descritos e comprovados na literatura. O território dos ianomâmis faz fronteira entre Brasil e Venezuela da seguinte forma, ao norte de Roraima, ao sul da Venezuela e ao nordeste da Amazônia do Brasil. A subsistência desses indígenas se dá por meio da riqueza da floresta amazônica aliada a respeitosa sabedoria praticada por eles repassadas de geração para geração e também do plantio de suas roças. Diante disso o objetivo é disseminar informações sobre a nocividade do mercúrio para a saúde dos ianomâmis nos últimos quatros anos, assim como, as causas que influenciam o estado de desnutrição, doenças e morte desses povos originários. A pesquisa bibliográfica foi realizada a partir de referencial teórico em livros e site confiáveis, como registros de uma realidade excludente e de possível extermínio. A pesquisa evidencia os malefícios causados na saúde dos ianomâmis e no ecossistema, pelos invasores garimpeiros nas terras indígenas
The Work from Home Revolution: WFH Starter Kit
Authors: Mohd Sharip Sharfizie , Mohd Rashid Nur Rasyida , Abdul Hamid Syahrul Bariah , Abdullah Asiah , Pungot Noor Hidayah 
Published: June 2023

The implications of the COVID-19 pandemic have greatly changed the norm in the employment system. Workers in both the public and private sectors are now adapted to the term "Work from Home" (WFH). Also, despite the little information on reliable practices for working from home, employees are nevertheless expected to perform at their highest level in accordance with the organizational goals. Therefore, this study is aimed to evaluate the need of establishing a guideline for WFH. A total of 178 employees from both private and government sectors were recruited in this survey. Findings showed that 69.1% of staff agreed their organization should provide them with proper guidelines in the implementation of WFH. It means that when they have specific guidelines it enables them to work more independently which also exhibits flexibility and creativity. As a conclusion, the developed and validated WFH manual handbook is able to become the main reference for employees for them to prepare physically and mentally while working efficiently from home.
155-OR: Remnant Cholesterol Predicts Major Cardiovascular Events in Cardiovascular Disease Patients with NAFLD
Authors: LARCHER BARBARA , MADER ARTHUR , SPRENGER LUKAS , VONBANK ALEXANDER , MAECHLER MAXIMILIAN , PLATTNER THOMAS , LEIHERER ANDREAS , MUENDLEIN AXEL , DREXEL HEINZ , SAELY CHRISTOPH H. 
Published: June 2023

Remnant cholesterol has attracted interest as a marker of cardiovascular event risk. The power of remnant cholesterol to predict major cardiovascular events (MACE) in patients with nonalcoholic fatty liver disease (NAFLD) is unclear and is addressed in the present study. We enrolled a high-risk cohort of 1420 consecutive patients with established cardiovascular disease (1183 patients with stable coronary artery disease and 237 patients with peripheral artery disease). NAFLD was diagnosed using the validated fatty liver index (FLI). Prospectively, MACE including cardiovascular death, non-fatal myocardial infarction and non-fatal stroke were recorded over a mean follow-up period of 9.6±5.0 years. At baseline, remnant cholesterol was significantly higher in patients with NAFLD (n=683) than in patients who did not have NAFLD (29 ±.26 mg/dl vs. 19 ±16 mg/dl; p&lt;0.001). During follow-up, 570 of our patients suffered MACE. Remnant cholesterol in Cox regression models adjusting for age, sex, hypertension, smoking, diabetes mellitus, body mass index and LDL cholesterol independently predicted MACE in the total study population (standardized adjusted HR 1.15 [1.06-1.24], p&lt;0.001), and both in patients with NAFLD as well as in those who did not have NAFLD (standardized adjusted HRs 1.16 [1.03-1.30], p=0.012 and 1.14 [1.02-1.27], p=0.028, respectively). From our data we conclude that remnant cholesterol is a predictor of MACE in cardiovascular disease patients with NAFLD.

Disclosure
B. Larcher: None. A. Mader: None. L. Sprenger: None. A. Vonbank: None. M. Maechler: None. T. Plattner: None. A. Leiherer: None. A. Muendlein: None. H. Drexel: None. C.H. Saely: None.
1599-P: Regulation of Mitochondrial Dynamics Ameliorates Hepatic Steatosis through TFEB Activation
Authors: YOO JIN , CHEOL HWANG YOU 
Published: June 2023

Nonalcoholic fatty liver disease (NAFLD) is a common cause of liver disease that is closely related to metabolic syndromes, obesity, and type 2diabetes. There is strong evidence that mitochondrial dysfunction plays a significant role in the development and progression of NAFLD. Recently, growing evidence suggests that the TFEB plays a pivotal role in mitochondrial dynamics. In this study, we investigated that mitochondrial dynamics play the potential role and mechanisms of TFEB in the amelioration of NAFLD. FFA increased expression of mitochondrial fission proteins p-Drp1, Fis1 and decreased expression of fusion proteins OPA1, Mfn2 and inhibition of TFEB activation. Mitotracker stain significantly increased in the proportion of cells with fragmented mitochondria in FFA-treated cells. HFD-fed mice displayed histology consistent with pathological hepatic steatosis. EM analysis indicated that HFD-fed mitochondria tended to be shorter and more round than ND-fed mitochondria. Western blot analyses reveal increased expression of the fission proteins, p-Drp1, Fis1, and significantly decreased in the fusion protein, Mfn2 and OPA1 in HFD-fed group. In vivo Tfeb knockout dramatically increased hepatic fat accumulation, liver ballooning in HFD-fed mice. EM analysis showed that HFD-fed Tfeb knockout mice had more rounded and swollen mitochondria, indicating that TFEB was dependent on the regulation of mitochondrial fragmentation. In vivo Tfeb knockout reveal significantly increased expression of the fission proteins in HFD-fed group. To demonstrated the direct regulatory mechanism of mitochondrial dynamics and TFEB activation, we used siRNA DRP1 and Mdivi-1. Inhibition of Drp1 promotes mitochondrial fusion, increased expression of fusion protein and reduced fat accumulation and activated TFEB. These results suggest a role in improving hepatic steatosis through regulation of TFEB-mediated mitochondrial dynamics in NAFLD.

Disclosure
J.Yoo: Other Relationship; American Diabetes Association. Y.Hwang: None.

Funding
National Research Foundation of Korea (2022R1I1A1A01069899)