bluuebunny/crossref_metadata_2025_split huggingface dataset:
N‐doped flexible triazine‐based porous polymer for thermal energy storage
Authors: Jiang Xiaowei , Liu Zhihong , Tan Yujiao , Chen Xiaosong , Huang Ping , Ma Libo , Xiong Xu , Gao Weibin , Tao Yu , Lu Hongxia , Dai Zheng 
Published: July 2023

AbstractNitrogen atoms has been widely adopted in preparation of porous organic polymers (POPs). In our study, flexible nitrogen porous organic polymers (FNPOPs) with high nitrogen content are synthesized by using acetic acid both as solvent and catalyst. The materials show moderate Brunauer–Emmett–Teller (BET) surface area and outstanding thermal stabilities (Td: 330°C). FNPOP‐2 is prepared into phase change material (PCM) composites by self‐adsorption method. From differential scanning calorimetry (DSC) analysis, the PCM composites show high encapsulation ratio (55.2 wt%) and latent heat (135.7 J g−1) due to flexible structure and high nitrogen atomic content. Furthermore, the thermal energy storage properties of all PCM composites remained after several thermal cycles. In general, FNPOPs have potential applications in phase change materials adsorption and thermal energy storage.
Spatial patterns of intrinsic brain activity in rats with capsular stroke
Authors: Ma Jie , Li Xue‐Jia , Liu Wen‐Xin , Teng Fei , Hua Xu‐Yun 
Published: July 2023

AbstractBackgroundTo explore the neural changes of brain activity in rats with circumscribed capsular infarcts to find a new therapeutic target for promoting the functional recovery.MethodsA total of 18 capsular infarct rats and 18 normal rats were conducted in this study. All animal use procedures were strictly in accordance with the guide for the care and use of laboratory animals. After establishing the photothrombotic capsular infarct model, the functional magnetic resonance imaging (fMRI) data were collected and analyzed.ResultsThe fMRI results indicated that the passive movement would induce strong activation in caudate, putamen, frontal association somatosensory cortex, thalamus dorsolateral, and thalamus midline dorsal in control group, and the passive movement would only induce limited activation mostly in somatosensory cortex, thalamus dorsolateral, and thalamus midline dorsal in capsular infarct models. Capsular infarct makes the cortical activity weaken in sensory‐related cortex and subcortical nuclei, including capsular area and thalamus.ConclusionsSuch findings imply that the posterior limb of internal capsule (PLIC) is connected to these structures in function, interacts together with them, and, accordingly, the lesion of PLIC manifests the related symptoms.
Polycyclic Aromatic Hydrocarbons Occurrences in Biomass Char and Its Mitigation Approaches: A Mini Review
Authors: Mohd Nor Azman Nur Aina Najwa , Asmadi Mohd , Amin Nor Aishah Saidina , Shamjuddin Amnani , Mohammad Zainol Muzakkir , Phaiboonsilpa Natthanon , Kawamoto Haruo 
Published: July 2023

AbstractBiochar is a porous fine‐grained substance produced from the pyrolysis technology of biomass that can be commercially used as a soil conditioner to promote soil fertility. Biochar is characterized by high carbon content, stability, and porosity. However, organic pollutants residue of polycyclic aromatic hydrocarbons (PAHs) is also formed during the pyrolysis of biochar. The high concentration of PAHs adversely degrades the quality of biochar for soil amendment application. Meanwhile, highly toxic‐PAHs concentration may pose a potential threat to both human health and the environment. The total PAHs yield is mainly influenced by the pyrolysis condition and feedstock resource. This review aims to discuss the conversion pyrolysis technology of biochar and factors that may influence the PAHs formation. The key research findings from this literature will lead to some strategies to minimize the PAHs compound in biochar by controlling the pyrolysis conditions through higher pyrolysis temperature, carrier gas flow, and prolonged pyrolysis time or by selecting suitable feedstock with lower lignin content.
Nanocarbon in Sodium‐ion Batteries – A Review. Part 2: One, Two, and Three‐dimensional Nanocarbons
Authors: Thangaraj Baskar , Solomon Pravin Raj , Hassan Jamal 
Published: July 2023

AbstractNanocarbons play a significant role in the development of alternative, clean and sustainable energy technologies. The utility of low‐dimensional nanostructured carbons (one‐, two‐ and three‐dimensional) in the new generation of batteries have shown great potential due to their physicochemical and electrochemical properties as well as high safety. The electrodes made from nanostructured carbon materials with different dimensions, size and structures offer enhanced ionic transport and electronic conductivity as compared to conventional batteries. They also enable the occupation of all intercalation sites available in the particle which leads to high specific capacities, fast ion diffusion, superior rate capability and long‐term cyclability. The carbonaceous nanosized active materials are important to enhance the electrical conductivity of the electrode materials and buffer the structural change and strain during sodium insertion and extraction. Application potentialities of different low‐dimensional nanostructured carbons in sodium‐ion batteries (SIBs) are discussed in this part II. It also deals with the modifications made on the carbonaceous material by doping with heteroatoms, expressing diversified morphologies with porous materials or compositing with organic or inorganic species.
E3 ubiquitin ligase neural precursor cell‐expressed developmentally downregulated gene 4 motivates FOXA1 ubiquitination and restrains proliferation of diffuse large B‐cell lymphoma cells via the Wnt/β‐Catenin pathway
Authors: Yang Li , Li Jun Nan 
Published: July 2023

AbstractNeural precursor cell‐expressed developmentally downregulated gene 4 (NEDD4) is an E3 ubiquitin ligase that recognizes substrates via protein–protein interactions and takes part in tumor development. This study aims to clarify NEDD4's functions in diffuse large B‐cell lymphoma (DLBCL) and its downstream mechanisms. Collection of 53 DLBCL tissues and adjacent normal lymphoid tissues, and detection of NEDD4 and Forkhead box protein A1 (FOXA1) in the tissues were conducted. The selection of DLBCL cells was for FARAGE, and test of cells' advancement was after transfection. Analysis of NEDD4 and FOXA1's link, and test of Wnt/β‐catenin pathway were implemented. In vivo tumor xenograft experiments were put into effect. Detection of the pathological conditions of tumor tissues and the positive Ki67 in the family was implemented. It came out NEDD4 was reduced in DLBCL tissues and cell lines, and FOXA1 was elevated; Enhancing NEDD4 or repressing FOXA1 refrained DLBCL cells' advancement; NEDD4 could combine with FOXA1 and trigger its ubiquitination and degradation; NEDD4 inactivates the Wnt/β‐catenin pathway by motivating FOXA1 ubiquitination; NEDD4 enhancement refrained DLBCL growth in vivo. In conclusion, the E3 ubiquitin ligase NEDD4 accelerates FOXA1 ubiquitination but refrains DLBCL cell proliferation via the Wnt/β‐Catenin pathway.
Superhydrophilic and Superaerophobic Ru‐Loaded NiCo Bimetallic Hydroxide Achieves Efficient Hydrogen Evolution over All pH Ranges
Authors: Zhang Mingyue , Gao Yong , Li Jingjing , Xia Yujiao , Yang Ling , Jiang Cheng , Huang Xianli , Wang Tao , He Jianping 
Published: July 2023

AbstractRealizing an effective, binder‐free, and super‐wetting electrocatalyst for the hydrogen evolution reaction (HER) at full pH is essential for the creation of clean hydrogen. In this study, the Ru‐loaded NiCo bimetallic hydroxide (Ru@NiCo‐BH) catalyst was prepared by spontaneous redox reaction. The chemical interaction between Ru NPs and NiCo‐BH by the Ru−O−M (M=Ni, Co) interface bond, the electron‐rich Ru active site, and the multi‐channel nickel foam carrier make the superhydrophilic and superaerophobic surface advantageous for mass transfer in the HER process. Therefore, Ru@NiCo‐BH has remarkable HER activity, with low overpotential of 29, 68 and 80 mV, a 10 mA cm−2 current density can be obtained in alkaline, neutral and acidic electrolytes respectively. This work provides a reference for the rational development of universal electrocatalysts for hydrogen evolution in the all pH ranges through simple design strategies.
Diastereoselective Petasis‐Borono‐Mannich Crotylation Reactions of Chiral α‐Heteroatom (F, OBz, OH) Aldehydes: Rapid Access to Valuable Mono and Bicyclic Heterocyclic Scaffolds
Authors: Chevis Philip J. , Chao Chi Bong Eric , Richardson Christopher , Hyland Christopher J. T. , Lee Richmond , Pyne Stephen G. 
Published: July 2023

AbstractThe crotylation reactions of chiral α‐F, α‐OBz and α‐OH aldehydes under Petasis‐borono‐Mannich conditions using (E)‐ or (Z)‐crotylboronates and primary amines resulted in γ‐addition products in high dr and high er. α‐F and α‐OBz aldehydes gave 1,2‐anti‐2,3‐syn and 1,2‐anti‐2,3‐anti, products, respectively while an α‐OH aldehyde gave 1,2‐syn‐2,3‐syn products. The stereochemical outcomes of reactions of the former aldehydes can be explained using a six‐membered ring transition state (TS) model in which a Cornforth‐like conformation around the imine intermediate is favoured resulting in 1,2‐anti products. The 2,3‐stereochemical outcome is dependent upon the geometry of the crotylboronate. These TS models were also supported by DFT calculations. The stereochemical outcomes of reactions employing an α‐OH aldehyde can be rationalised as occurring via an open‐TS involving H‐bonding in the imine intermediate between the α‐OH group and the imine N atom. Representative products were converted to highly functionalized 1,2,3,6‐tetrahydropyridines and 3H‐oxazolo[3,4‐a]pyridine‐3‐ones which will be valuable scaffolds in synthesis.
Investigations of the Photothermal Properties of a Series of Molecular Gold‐bis(dithiolene) Complexes Absorbing in the NIR‐III Region
Authors: Pluta Jean‐Baptiste , Guechaichia Romain , Vacher Antoine , Bellec Nathalie , Cammas‐Marion Sandrine , Camerel Franck 
Published: July 2023

AbstractThe photothermal properties of a series of neutral radical gold‐bis(dithiolene) complexes absorbing in the near‐infrared‐III window (1550–1870 nm) have been investigated. This class of complexes was found to be good photothermal agents (PTAs) in toluene under 1600 nm laser irradiation with photothermal efficiencies around 40 and 60 % depending on the nature of the dithiolene ligand. To the best of our knowledge, these complexes are the first small molecular photothermal agents to absorb so far into the near infrared. To test their applicability in water, these hydrophobic complexes have been encapsulated into nanoparticles constituted by amphiphilic block‐copolymers. Stable suspensions of polymeric nanoparticles (NPs) encapsulating the gold‐bis(dithiolene) complexes have been prepared which show a diameter around 100 nm. The encapsulation rate was found to be strongly dependent on the nature of the dithiolene ligands. The photothermal properties of the aqueous suspensions containing gold‐bis(dithiolene) complexes were then studied under 1600 nm laser irradiation. These studies demonstrate that water has strong photothermal activity in the NIR‐III region that, cannot be overcome even with the addition of gold complexes displaying good photothermal properties.
Facile Synthesis of Enantiomerically Pure P‐Chiral 1‐Alkoxy‐2,3‐dihydrophospholes via Nucleophilic P−N Bond Cleavage of a 1‐Phospha‐2‐azanorbornene
Authors: Ramazanova Kyzgaldak , Lönnecke Peter , Hey‐Hawkins Evamarie 
Published: July 2023

AbstractInvited for the cover of this issue is the group of Prof. Evamarie Hey‐Hawkins at Leipzig University. The image depicts a deer with diastereomeric antlers. Read the full text of the article at 10.1002/chem.202300790.
Characterization of membrane‐interaction mechanisms of proteins using vacuum‐ultraviolet circular dichroism spectroscopy
Authors: Kumashiro Munehiro , Matsuo Koichi 
Published: July 2023

AbstractProtein‐membrane interactions play an important role in various biological phenomena, such as material transport, demyelinating diseases, and antimicrobial activity. We combined vacuum‐ultraviolet circular dichroism (VUVCD) spectroscopy with theoretical (e.g., molecular dynamics and neural networks) and polarization experimental (e.g., linear dichroism and fluorescence anisotropy) methods to characterize the membrane interaction mechanisms of three soluble proteins (or peptides). α1‐Acid glycoprotein has the drug‐binding ability, but the combination of VUVCD and neural‐network method revealed that the membrane interaction causes the extension of helix in the N‐terminal region, which reduces the binding ability. Myelin basic protein (MBP) is an essential component of the myelin sheath with a multi‐layered structure. Molecular dynamics simulations using a VUVCD‐guided system showed that MBP forms two amphiphilic and three non‐amphiphilic helices as membrane interaction sites. These multivalent interactions may allow MBP to interact with two opposing membrane leaflets, contributing to the formation of a multi‐layered myelin structure. The antimicrobial peptide magainin 2 interacts with the bacterial membrane, causing damage to its structure. VUVCD analysis revealed that the M2 peptides assemble in the membrane and turn into oligomers with a β‐strand structure. Linear dichroism and fluorescence anisotropy suggested that the oligomers are inserted into the hydrophobic core of the membrane, disrupting the bacterial membrane. Overall, our findings demonstrate that VUVCD and its combination with theoretical and polarization experimental methods pave the way for unraveling the molecular mechanisms of biological phenomena related to protein‐membrane interactions.
Hirschhornsalz (baker's ammonia) and the chemical equilibrium – experiments using digital pressure sensors
Authors: Rautenstrauch Hanne , Rebenstorff Anne 
Published: July 2023

AbstractDigitale Messsensoren bieten das Potential, schwer verständliche oder schwer beobachtbare Phänomene, wie die Bildung farbloser Gase oder die Erhöhung oder Erniedrigung des Drucks, während einer chemischen Reaktion sichtbar und somit besser begreifbar zu machen. Zudem kann durch den Einsatz digitaler Messsensoren ein neuer Blick auf altbewährte Experimente ermöglicht werden. In diesem Beitrag werden dazu Experimente zum chemischen Gleichgewicht mit Hirschhornsalz unter Verwendung eines digitalen Drucksensors vorgestellt.
Generalization of waving‐plate theory to multiple interacting swimmers
Authors: Baddoo Peter J. , Moore Nicholas J. , Oza Anand U. , Crowdy Darren G. 
Published: July 2023

AbstractEarly research in aerodynamics and biological propulsion was dramatically advanced by the analytical solutions of Theodorsen, von Kármán, Wu and others. While these classical solutions apply only to isolated swimmers, the flow interactions between multiple swimmers are relevant to many practical applications, including the schooling and flocking of animal collectives. In this work, we derive a class of solutions that describe the hydrodynamic interactions between an arbitrary number of swimmers in a two‐dimensional inviscid fluid. Our approach is rooted in multiply‐connected complex analysis and exploits several recent results. Specifically, the transcendental (Schottky–Klein) prime function serves as the basic building block to construct the appropriate conformal maps and leading‐edge‐suction functions, which allows us to solve the modified Schwarz problem that arises. As such, our solutions generalize classical thin aerofoil theory, specifically Wu's waving‐plate analysis, to the case of multiple swimmers. For the case of a pair of interacting swimmers, we develop an efficient numerical implementation that allows rapid computations of the forces on each swimmer. We investigate flow‐mediated equilibria and find excellent agreement between our new solutions and previously reported experimental results. Our solutions recover and unify disparate results in the literature, thereby opening the door for future studies into the interactions between multiple swimmers.
Protein‐Inspired Control over Synthetic Polymer Folding for Structured Functional Nanoparticles in Water
Authors: Wijker Stefan , Palmans Anja R. A. 
Published: July 2023

AbstractThe folding of proteins into functional nanoparticles with defined 3D structures has inspired chemists to create simple synthetic systems mimicking protein properties. The folding of polymers into nanoparticles in water proceeds via different strategies, resulting in the global compaction of the polymer chain. Herein, we review the different methods available to control the conformation of synthetic polymers and collapse/fold them into structured, functional nanoparticles, such as hydrophobic collapse, supramolecular self‐assembly, and covalent cross‐linking. A comparison is made between the design principles of protein folding to synthetic polymer folding and the formation of structured nanocompartments in water, highlighting similarities and differences in design and function. We also focus on the importance of structure for functional stability and diverse applications in complex media and cellular environments.
The cost‐effectiveness of a virtual intervention to prevent eating disorders in young women in Sweden
Authors: Martínez de Alva Patricio , Ghaderi Ata , Andersson Gerhard , Feldman Inna , Sampaio Filipa 
Published: July 2023

AbstractObjectiveTo determine the cost‐effectiveness of a virtual version of the Body Project (vBP), a cognitive dissonance‐based program, to prevent eating disorders (ED) among young women with a subjective sense of body dissatisfaction in the Swedish context.MethodA decision tree combined with a Markov model was developed to estimate the cost‐effectiveness of the vBP in a clinical trial population of 149 young women (mean age 17 years) with body image concerns. Treatment effect was modeled using data from a trial investigating the effects of vBP compared to expressive writing (EW) and a do‐nothing alternative. Population characteristics and intervention costs were sourced from the trial. Other parameters, including utilities, treatment costs for ED, and mortality were sourced from the literature. The model predicted the costs and quality‐adjusted life years (QALYs) related to the prevention of incidence of ED in the modeled population until they reached 25 years of age. The study used both a cost‐utility and return on investment (ROI) framework.ResultsIn total, vBP yielded lower costs and larger QALYs than the alternatives. The ROI analysis denoted a return of US $152 for every USD invested in vBP over 8 years against the do‐nothing alternative and US $105 against EW.DiscussionvBP is likely to be cost‐effective compared to both EW and a do‐nothing alternative. The ROI from vBP is substantial and could be attractive information for decision makers for implementation of this intervention for young females at risk of developing ED.Public SignificanceThis study estimates that the vBP is cost‐effective for the prevention of eating disorders among young women in the Swedish setting, and thus is a good investment of public resources.
eDNA metabarcoding reveals differences in fish diversity and community structure in heterogeneous habitat areas shaped by cascade hydropower
Authors: Cheng Ruli , Luo Yang , Zhang Yufeng , Li Qinghua , Li Yingwen , Shen Yanjun 
Published: July 2023

AbstractFreshwater ecosystems are under great threat from humans, among which habitat heterogeneity is the most obvious, being one of the important reasons for the decline of fish diversity. This phenomenon is particularly prominent in the Wujiang River, where the continuous rapids of the mainstream have been divided into 12 mutually isolated sections by 11 cascade hydropower reservoirs. Based on the fact that conventional survey methods are more harmful to the ecological environment, the efficient and noninvasive environmental DNA metabarcoding (eDNA) approach was used in this study to conduct an aquatic ecological survey of the 12 river sections of the mainstream of the Wujiang River. A total of 2299 operational taxonomic units (OTUs) were obtained, corresponding to 97 species, including four nationally protected fish species and 12 alien species. The results indicate that the fish community structure of the Wujiang River mainstream, which was originally dominated by rheophilic fish species, has been changed. And there are differences in fish species diversity and species composition among the reservoir areas of the mainstream of the Wujiang River. The fish species in the area have gradually declined under the influence of anthropogenic factors such as terraced hydropower and overfishing. The fish populations consequently have demonstrated a tendency to be species miniaturized, and the indigenous fish are severely threatened. In addition, the fish composition monitored by the eDNA approach was found to be close to the fish composition of historical information on the Wujiang River, indicating that eDNA approach may be used as a complementary tool to conventional methods in this basin.
The Evolution of Phosphite‐Oxazoline Ligands for the Pd‐Allylic Substitution and Their Application in Building Chiral Molecules
Authors: Biosca Maria , Tarr Daniel , Pàmies Oscar , Diéguez Montserrat 
Published: July 2023

AbstractPd‐catalyzed asymmetric allylic substitution (AAS) is a highly effective method for producing chiral molecules with alkene‐substituted frameworks which can be further derivatized. However, its stereochemical outcome is affected by the steric requirements of the substrate and only a narrow set of nucleophiles yield excellent enantioselectivities. In this regard, phosphite‐oxazolines have emerged as strong candidates to be privileged ligands for this process, providing results that surpass most of the previously published studies. They have provided high enantiocontrol when used in the Pd‐AAS of several hindered and unhindered substrates, using a wide range of C‐, O‐, and N‐nucleophiles. In this concept, we review and discuss the current progress made in the design of tailor‐made phosphite‐oxazoline ligand libraries for the Pd‐AAS of a broad range of substrates and nucleophiles and its application in the construction of chiral complex molecules.
Total Synthesis of Spiroalkaloids Lycibarbarines A–C
Authors: Nie Pengpeng , Zhao Chuanfang , Yu Shuai , Liu Jun , Du Yuguo 
Published: July 2023

AbstractThe concise and efficient synthesis of tetrahydroquinoline alkaloids lycibarbarines A−C has been accomplished in four steps from a common intermediate derived from commercially available 2‐deoxy‐D‐ribose and 8‐hydroxyquinoline. For the synthesis of the unique tetracyclic spiro‐heterocycle skeleton we employed a synthetic strategy that features two key transformations: iodomethyllithium‐based homologation of lactone / N‐alkylation to access tetracyclic spiro‐heterocycle skeleton in one step and one‐pot acetonide deprotection, hemiacetal formation, and spirocyclization cascade process.