bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quality Indicators in Three Coffee Production Agrosystems
Authors: Fernández Abraham de Jesus Romero , González Rogelio Carrillo , Cabrera Braulio Edgar Herrera , Chávez Ma. del Carmen González 
Published: February 2023

Abstract
Healthy soil is a fundamental resource against hunger; it contributes to mitigating climate change and ensures sustainable production. The economic and social importance of coffee requires taking measures to promote its sustainable production. Shaded coffee production systems offer valuable ecosystem services indispensable for product diversification. In this context, we compared the quality of the soil, foliage, and seed of three coffee production systems: under mango shade (CM), under banana shade (CB), and under the full sun (CS). Using principal component analysis, we selected the minimum data set to designate quality indicators. For soil, the quality indicators were pH, cation exchange capacity, N content, the concentration of Ca, Mg, K, Fe, soil moisture, percentage specific conductance, soil penetration resistance and the number of worms. Foliar indicators corresponded to N content, the concentration of K, Ca, Fe, Cu, and Chlorophyll b; and seed indicators were concentration of P, K, Ca, Mg, Zn, and Cu. The soil quality index was moderate in the shaded coffee production systems, but deficient in the CS system. Foliar quality was very high in the CM system, moderate in CB and low in CS. Seed yield was low in the three systems. This research shows the main indicators influencing not only soil quality but also plant and seed nutrition in the three systems. Knowledge of the indices will allow establishing of better agronomic management practices in the shaded systems, improving soil fertility, plant nutrition, and coffee seed quality.
Accumulation Characteristics and Health significance of As, Cd and Cr Elements in Different Plants
Authors: Wang Lu , Zou Runyan , Han Yuejiang , Tan Zhengxi , Xie Yingkai , Yang Hao , Su Huiyue , Yu Huan , Zhu Zhiqiang , Song Yingqiang 
Published: February 2023

Abstract
To evaluate the impacts of vegetable and soil variables on phytoaccumulation of arsenic (As), cadmium (Cd) and chromium (Cr) and identify their interactions and predictors, 33 paired soil-vegetable samples were collected from the production areas of celery (Oenanthe javanica), green onion (Allium), pak choy (Brassica rapa subsp. chinensis), rape (Brassica campestris L.) and spinach (Spinacia olearacea) in the Wuqing District of Tianjin, China. The concentrations (mean ± sd in mg kg-1) of As, Cd, and Cr were 12.9 ± 2.4, 0.21 ± 0.19, 68.2 ± 11.2 in soils, respectively, higher than their soil backgrounds, and 0.19 ± 0.13, 0.17 ± 0.11, and 1.33 ± 0.94 in shoots (leaves & stems) of all vegetables, respectively. Only Pak Choy’s Cd was significantly higher than its soil concentration and threshold. All vegetables, except green onion, with the lowest concentration of As, Cd, and Cr have been heavily contaminated with Cr. For all vegetables except spinach, Cd concentration in shoots can be well predicted with 0.1M HCl extracted soil Cd (clCd) (R2 > 0.75) with soil clNi; and shoot Cr concentration with shoot Fe (stFe) for celery, pok choy, rape, and spinach (R2 > 0.90).Generally, the concentration of As, Cd, and Cr in shoots depends not only on the availability of their specific forms in soil and soil pH but also on the interactions with other elements (especially Fe) in shoots, despite their variations with vegetable species. Both Cd and Cr have a high accumulation potential, which can be better predicted with either 0.1M HCl extractable soil Cd or Fe concentration in shoots. So, how a trace element interacts with other ingredients and its specific form in the soil should be seen as essential factors in how it gets into the shoots.
Living Alone and Loneliness in Predicting Health-Related Quality of Life: Results from the Healthy Aging Longitudinal Study in Taiwan (HALST)
Authors: Tseng Han-Yun , Lee Chun-Yi , Wu Chi-Shin , Wu I-Chien , Chang Hsing-Yi , Hsu Chih-Cheng , Hsiung Chao Agnes 
Published: February 2023

Abstract
Purpose.
This study examined two related but distinct features of social isolation – living alone and loneliness – concerning their unique and joint effects on predicting health-related quality of life (HRQoL). In addition, we examined the moderating and mediating role of loneliness in the associations between living alone and HRQoL.
Method.
Analyses were with a nationally representative sample of 5,012 community-residing adults aged 55 and older (Mage = 59.3, SD = 8.1) and with their follow-up data 3.2 years later.
Results.
At baseline, 9% (n = 508) reported living alone, and 10.3% (n = 586) reported feeling lonely. 2.5% (n = 130) reported both living alone and feeling lonely. A series of regression showed that loneliness was consistently associated with lower physical (PCS) and mental (MCS) components of HRQoL, concurrently and longitudinally, whereas living alone was only associated with lower PCS 3.2 years later. Moderation analysis showed compounded effects of loneliness and living alone in predicting lower MCS. Mediation analyses revealed a cascading effect where living alone was associated with concurrent and subsequent loneliness, which, in turn, was associated with lower PCS and MCS 3.2 years later.
Conclusion.
Loneliness appeared to be a more potent predictor of lower HRQoL in later life. Nevertheless, living alone could indirectly worsen adults’ HRQoL by either exacerbating the negative impacts of loneliness or triggering a sense of prolonged loneliness predicting lower HRQoL. For practice, programs and policies to improve adults’ HRQoL should pay special attention to older adults who report loneliness, especially those who live alone.
RAD-Blood: a database to identify RNAs in blood as potential biomarkers of Alzheimer's disease by integrating bulk- and single-cell transcriptome profile
Authors: Duan Ting-Ting , Li Jin-Quan , Chu Jin-Yu , Li Xin-Wen , Pan Shi-Yao , Tan Wei , Zeng Yan , Hu Fei-Fei 
Published: February 2023

Abstract
Background
The early diagnosis of Alzheimer's disease (AD) in large-scale high-risk population is a major challenge. Blood-based biomarkers could enable widespread testing for AD. RNA-seq technology is becoming an effective method in investigating diagnostic biomarkers for diseases, but platforms exploring RNA-seq data in AD blood are lacking.
Methods
We collected the raw RNA-seq data in the blood of AD patients or AD mouse models, mild cognitive impairment (MCI) patients, and normal people or wild type mouse from the Gene Expression Omnibus (GEO) and Synapse databases. And the RNA-seq data was analyzed by the standard pipeline. We applied R-Shiny to develop the website of RAD-Blood (RNA-seq analysis of AD blood, http://www.bioinform.cn/RAD-Blood/) to present the plentiful analysis results.
Results
RAD-Blood was specifically designed to analyze existing blood RNA-seq data sets (mRNA-seq, miRNA-seq, and scRNA-seq) from patients and mouse models with AD pathology. The RAD-Blood provides differential expression, gene set enrichment, immune abundance and its correlation with gene expression, cell type annotation, T cell receptor, and cell communication analyses for RNA-seq data in AD/MCI/normal blood, with rich results forms and colorful figures. We used a case study to show the capacity of RAD-Blood in finding blood biomarkers in AD/MCI blood. By using RAD-Blood, we found 274 protein-coding genes whose mRNA expression was consistently up-regulated or down-regulated from normal to MCI to AD. Among the consistently down-regulated genes, four are the markers of the blood erythroid cell. Compared with normal people, the population of erythroid cells in AD patients decreased. Despite the reduction in cell count, interactions between blood erythroid cells with other cells increased dramatically, which is mainly mediated through the major histocompatibility complex I (MHC-I) signaling pathway. These findings have not been reported by existing studies, which suggests that RAD-Blood is a solution for finding potential novel signatures in the blood of AD and MCI.
Conclusions
RAD-Blood is a user-friendly web server for multi-level analysis and visualization of gene/miRNA expression and immune profile in AD blood, and allows broad utility in exploring potential AD blood biomarkers, testing hypotheses, guiding experiment design, and investigating the peripheral pathogenic mechanisms and proposing potential early diagnosis standard of AD.
Prevalence of Serum Immunoglobulin A Antibodies Reactive to Severe Acute Respiratory Syndrome Coronavirus 2 in Healthy College Students and Employees: A Preliminary Study in Sudan
Authors: Mahmoud Motaz Mohammed , Yasin Ola Hassan , Atabani Nafisa Mahmoud , Mohammed Riyadh Abdulsalam , Mohammed Samah said Ahmed , Bakheit Abdullah M , Hajhamed Nooh Mohamed , Ismail Salahaldeen , Mengistu Samuel Tekle , Hamida Mohammed Elfatih 
Published: February 2023

Abstract
The SARS-CoV-2-caused COVID-19 pandemic has posed a severe danger to worldwide public health. While several nations have recorded high rates of occurrence, Sudan has reported a comparably low number of instances. To investigate this phenomenon, we conducted a preliminary investigation to determine the frequency of immunoglobulin A (IgA) antibodies reactive to SARS-CoV-2 in healthy Sudanese college students and employees. Using an enzyme-linked immunosorbent assay, we collected blood samples from 80 individuals and evaluated serum IgA antibodies reactive to the receptor binding region of SARS-CoV-2 spike-1 subunit proteins. Our primary finding was that 17.5% (95% CI 9.97–27.6) of those who asymptomatic to SARS-CoV-2 tested positive for serum IgA antibodies, with a broad range of values of the grand median of the optical density (OD) of 0.083 (IQR: 0.049–0.13) ng/ml. We discovered a downward trend in antibody positivity with increasing age. According to our early findings, IgA antibodies reactive to SARS-CoV-2 are found in asymptomatic Sudanese college students and staff. This discovery may shed light on the comparatively low prevalence of COVID-19 in Sudan. Further study is needed to look into the potential protective impact of pre-existing IgA antibodies against SARS-CoV-2 and to understand the underlying processes.
CONTESTATION AND REPRESENTATION
Authors: Jahroni Jajang , Faisal Bakti Andi M. 
Published: February 2023

This article seeks to elaborate the roles of some Muslim scholars and activists who, thanks to the advancement of internet technology, have shaped new forms of religious life in Indonesia. Using social media platforms such as YouTube, Instagram, Facebook, and Twitter, they advocate their ideas and attract followers from Muslim groups. These Muslims are divided into four ideologies, namely conservative, moderate, liberal and traditionalist. As this article argues, thanks to their online activism, they successfully shape a new religious authority replacing the old model. Nevertheless, as this article also suggests, religious activism on online media outlets does not lead to the pluralism of religious views and understandings. In contrast, this activism creates the so called echo chamber or isolated bubbles, which means that the activists’ voices are only observed by their limited followers. Taking the activism of most popular conservative activists Felix Siauw, it sees that his view reverberates only among his social media followers and fails to attract those who embrace other views orideologies. The followers of the moderate, the liberal, and the traditionalist on the other hand tend to be heterogenous creating a noisy minority. This leads to the vibrant and robust religious discourses.
Procedure for selecting a rational technological mode for the processing of cast iron melt on the basis of graph-analytical processing of the data of serial smeltings
Authors: Nikolaiev Denys 
Published: February 2023

The object of research: cast iron grade DSTU EN 1561 (EN-GJL-200), used for the manufacture of body parts for mechanical engineering.
Investigated problem: the choice of the technological mode of the process of producing cast iron under conditions of multifactorial influence on the formation of its microstructure.
The main scientific results: A procedure for truncation of the influencing factors on the formation of the microstructure is proposed, which is a consistent reduction of data from serial smeltings to uniform conditions allowed by the actual data set. Common conditions mean the closeness of the chemical composition of the melt, which makes it possible to compare the effectiveness of the applied modifiers in combination with microalloying in terms of cast iron microstructure indicators. The proposed data truncation procedure made it possible, by creating conditions for comparing the efficiency of FeSi75 and FeSi65CaBaSr2 modifiers, to develop a rational technological regime for melt processing.
It has been established that the compared modifiers have the same effect on the size of graphite – its content is (50–51) μm, however, the use of FeSi65CaBaSr2 in combination with an alloying complex (0.27 %Cr+0.083 %Ni+0.048 %Ti+0.155 %Cu+0.018 %V ) makes it possible to obtain an average amount of pearlite of 96 % in the microstructure.
The area of practical use of the results of the study: the results obtained can be used in foundries or metallurgical shops of industrial enterprises as part of a general technology for producing cast iron of various grades, developed for cases of incomplete control of the quality of charge materials. Such a situation occurs, for example, when the charge is formed from dismantled armored vehicles that cannot be restored due to destruction on the battlefield.
Innovative technological product: iron smelting technology that allows the possibility of minimizing the cost of smelting in terms of the use of modifiers and alloying ferroalloys
The scope of the technological innovative product: technological regimes for the production of cast iron.
Impact of low birth weight and breastfeeding practices on the nutritional status of children aged 2 to 5 years in the slums
Authors: Vallepalli Chandrasekhar , Sumalini Mannem Meghana , Prathyusha T. V. D. , Deekala Ravi Sankar , Nagaraj Kondagunta 
Published: February 2023

Malnutrition among children in developing countries is a major public health problem, especially in India. Inappropriate feeding practices, in combination with other causes such as infection and food shortage, may be responsible for 1/3rd of malnutrition. Moreover, the risk of mortality is inversely related to children's height-for-age and weight-for-height.
The aim: To assess the nutritional status of children aged 2 to 5 years in the urban field practice area of SVIMS-Sri Padmavathi Medical College for Women, Tirupati and to determine the impact of low birth weight, breastfeeding practices and other related factors on the nutritional status of the above study population.
Materials and methods: This is a community-based observational cross-sectional study conducted among 282 children aged 2 to 5 years in the urban field practice area of SVIMS-Sri Padmavathi Medical College for Women, Tirupati. Socio-demographic data, Birth history, breastfeeding practices and anthropometric measurements were noted in the study questionnaire. Nutritional status was determined using HAZ, WHZ and WAZ scores of WHO child growth standards. Data was entered and analyzed using IBM SPSS Statistics 26 version to test for association between categorical variables, and a p-value < 0.05 was considered statistically significant.
Results: A total of 282 school children with mean age of 39.9 (+10.4) months participated in the study, of which 132 (46.8 %) were boys and 150 (53.2 %) were girls. This study observed exclusive breastfeeding in 193 (68.4 %) children. Prevalence of stunting, wasting and being underweight were 22 %, 12.4 % and 23.8 %, respectively. A statistically significant association was found between stunting (p=0.006) and underweight (p=0.001) with low birth weight children.
Conclusions: The present study revealed a high prevalence of malnutrition, especially stunting, a common outcome of long-term malnutrition among young children. Low birth weight and inappropriate breastfeeding practices result in long-term adverse consequences on the nutrition of preschool children, which should be prevented through appropriate strategies.
Comparison of serum copper levels between coronary artery disease patients and normal individuals: a case-control study
Authors: Rajan Zinnia Shivaji , Jaganathan Sowndharya , Arokiasamy Synthiya , Kandhi Suganya , Sasikala Pothanur Mayavan 
Published: February 2023

Cardiovascular diseases (CVD) are the leading causes of death in technologically developed and developing countries. Copper, an active redox element, is involved in energy production through various mechanisms. Copper and coronary artery disease can be associated directly, through its direct effect on the vascular endothelium, or indirectly through lipoprotein metabolism. Hence an evaluation of copper in the coronary artery disease individual is important.
The aim is to compare the relationship of serum copper levels between coronary artery disease patients and control individuals based on age, sex, hypertension and diabetes mellitus.
Materials and methods: The study design was a case-control study in which proven coronary artery disease patients attending cardiology OPD were selected as cases. Control individuals were mainly selected from the master health check-up. Serum copper levels, plasma glucose, cholesterol, serum triglycerides, and serum HDL & LDL cholesterol were done. Glycated haemoglobin (HbA1C) was also measured. The data were analyzed using IBM SPSS software version 24.
Result: The correlation of serum copper level with other quantitative parameters is determined by calculating Pearson’s correlation coefficient among cases and controls.
Conclusion: The serum copper level is significantly (p=0.001) higher in CAD patients than in age, sex, DM, and HT-matched controls. The serum copper level has a significant (p=0.001) effect on disease, and the adjusted odds ratio is 1.032 (CI 1.011–1.054). In addition, the serum copper level has a significant (0.01) negative correlation with LDL cholesterol and total cholesterol.
Improved method of brewing peanut mouth with blending fruit drink of a high degree of readiness
Authors: Zahorulko Andrii , Zagorulko Aleksey , Mikhaylov Valeriy , Rudska Nina , Dmytrevskyi Dmytro , Ibaiev Eldar , Tytarenko Nataliia 
Published: February 2023

The method of production of peanut paste with blended fruit and vegetable semi-finished products of high degree of readiness based on Jerusalem artichoke and cranberry obtained under conditions of low-temperature concentration has been improved. The production method is characterized by the process of concentration in a rotary-film apparatus at a temperature of 45...50 °C to a content of 28...30 % of dry substances within 1.75...2.00 minutes. The organoleptic evaluation of various recipe ratios of the selected raw materials revealed its optimal content in the semi-finished product (Jerusalem artichoke 65 %, cranberry 35 %), which has a uniform structure, a pleasant aroma of cranberry and Jerusalem artichoke, and its color is red-orange. The obtained fruit and vegetable semi-finished product of a high degree of readiness can be used as a base or additive in various food products of special purpose to increase their nutritional value and provide the products with a health-improving effect.
For the production of health-prophylactic peanut paste, a technological manufacturing scheme is proposed with the addition of Jerusalem artichoke and cranberry fruit and vegetable paste to its composition, which will further increase the health-prophylactic properties of the finished product, eliminate the use of sugar and other synthetic stabilizers in comparison with classical technology. The organoleptic evaluation of the received samples of peanut paste with blended fruit and vegetable semi-finished product of a high degree of readiness revealed a rational amount of the semi-finished product at the level of 25 %, while the product has a structured, homogeneous consistency and a pleasant yellow-orange color. The obtained product can be recommended for therapeutic and preventive purposes, as a cholesterol-lowering and immunomodulating agent
BVDV Impact on Feedlot Mortality and Morbidity
Authors: Loneragan Guy H. 
Published: February 2023

Bovine viral diarrhea virus (BVDV) contributes to the pathogenesis of a number of maladies such as bovine respiratory disease (BRD), reproductive wastage amd acute enteritis. The causative role of BVDV in BRD is of greatest concern to the feedlot industry because BRD is by far the greatest cause of morbidity and mortality in US feedlots. Up to 90% of morbidity and 75% of mortality is attirbutable to respiratory tract disease. More cattle are treated or die from BRD than all other conditions combined.
Despite our increased understanding of its pathogenesis, universal use of vaccines, and availability of efficacious antimicrobial drugs, the proportion of placements dying from respiratory disease has increased.
Development of an Esophageal Tube Feeder for use in Calves
Authors: Pedersen Rikke Engelbrecht , Agerholm Jørgen S. 
Published: February 2023

Disease and mortality in neonatal calves are often the consequences of insufficient passive immunization due to inadequate colostrum management. Disease prevalence and mortality can be reduced if colostrum is administered by an esophageal tube feeder a few hours after calving.
The Danish Agricultural Advisory Centre recommends that calves expected to have insufficient colostrum intake, be fed a sufficient volume of high quality colostrum by esophageal tube feeder.
To improve efficiency of esophageal tube feeding and increase calf welfare and performance, an interdisciplinary project was initiated aimed at development of a user-friendly, hygienic esophageal tube feeder for use in calves.
Vaccination Programs for Breeding Heifers using Combinations of Killed and Modified-Live BVDV Vaccines
Authors: Dubovi E. J. , Grohn Y. T. , Nydam D. V. 
Published: February 2023

Despite preventing morbidity and mortality in properly immunized cattle, sometimes bovine viral diarrhea virus (BVDV) vaccines have failed to prevent reproductive consequences of BVDV infection, in particular, persistently infected animals.
High (SN) titers may provide fetal protection in at-risk breeding heifers. Our objective was to test different types and sequences of administration of killed and modified-live virus (MLV) vaccines to determine which produced the greatest titer response.
Comparison Of Commercial ELISA Tests For Johne's Disease In Beef Cattle Herds
Authors: Heeb Matt , Austerman S. R. , Hall Jason , Evans R. 
Published: February 2023

The prevalence of Johne's disease throughout the United States has prompted the development of several USDA approved ELISA kits. These test kits are widely used in diagnostic labs throughout the country. As numbers of beef producers utilizing these ELISA tests to detect Johne's disease increase, it becomes important to critically evaluate the performance of these diagnostic tests specifically in beef cattle.
The aim of this study was to evaluate the specificity and agreement between the three commercially manufactured ELISA tests for Johne's in beef cattle herds. Two-thousand fifty-four sera samples were collected from six beef herds in Iowa, South Dakota and Georgia. The samples were ran according to manufacturer's recommendations. The results were evaluated based upon specificity in negative herds, and kappa statistics were calculated for both positive and negative herds. The specificities ranged between 90.48 and 9.41 %. Agreement between tests ranged from k-0.394-0.061 in negative herds and k-0.503-0.310 in positive herds. These data indicate a significant difference between commercial ELISA tests.