bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nurses' wound care competency in a sample of hospitals in Northern Vietnam
Authors: TD Phan , Chinh Nguyen Duc , Ha Truong Thi Mai , Thuy Mai TT , Notter Joy 
Published: February 2023

Background: This study aimed to investigate the current situation regarding wound care by nurses in eight hospitals in the north of Vietnam, in order to plan the training for nurses to enable them to achieve the National Basic Competency Standards for Nurses. Methods: A cross-sectional descriptive prospective study was conducted from June 2020 to October 2020, with nurses in eight hospitals in four provinces of Northern Vietnam – Hanoi, Quang Ninh, Thai Nguyen and Bac Ninh. Data were collected based on a checklist of direct observation of nurses who provide wound care. The two main indicators were the knowledge score and the practical capacity/competence of the nurses in wound care. Results: A total of 518 nurses participated in the study, the mean age was 32.25±7.31; with 438 (84.6%) being female. Clinical experience of less than 10 years was reported by 63.6%; college education level (diploma) was reported by 58.1%, university level by 28.2%; and post-university level by 4%. The highest mean scores for knowledge were found in the categories of health education for patients, followed by care of clean wounds, communication skills and team work, management and professional development and pressure ulcer wound care. Under the practice domain the highest mean scores were ability to plan wound care, followed by self-evaluation, identification of wound types and implementation of wound care plans. Conclusions and recommendations: The results showed that when judged against the competency standards, nurses' level of wound care competency needs to be improved. Also that there is a distinct theory–practice gap, which must be addressed. It is recommended that hospitals should conduct training for all nurses using the basic competency standards for Vietnamese nurses to improve the quality of care.
Existence and concentration behavior of positive solutions to Schrödinger-Poisson-Slater equations
Authors: Li Yiqing , Zhang Binlin , Han Xiumei 
Published: February 2023

Abstract
This article is directed to the study of the following Schrödinger-Poisson-Slater type equation:

−

ε

2

Δ
u
+
V

(

x

)

u
+

ε

−
α

(

I

α

∗
∣
u

∣

2

)

u
=
λ
∣
u

∣

p
−
1

u

in

R

N

,

-{\varepsilon }^{2}\Delta u+V\left(x)u+{\varepsilon }^{-\alpha }\left({I}_{\alpha }\ast | u{| }^{2})u=\lambda | u{| }^{p-1}u\hspace{1em}\hspace{0.1em}\text{in}\hspace{0.1em}\hspace{0.33em}{{\mathbb{R}}}^{N},

where

ε
,
λ
>
0

\varepsilon ,\lambda \gt 0

are parameters,

N
⩾
2

N\geqslant 2

,

(

α
+
6

)

/

(

α
+
2

)

<
p
<

2

∗

−
1

\left(\alpha +6)\hspace{0.1em}\text{/}\hspace{0.1em}\left(\alpha +2)\lt p\lt {2}^{\ast }-1

,

I

α

{I}_{\alpha }

is the Riesz potential with

0
<
α
<
N

0\lt \alpha \lt N

, and

V
∈
C

(

R

N

,
R

)

V\in {\mathcal{C}}\left({{\mathbb{R}}}^{N},{\mathbb{R}})

. By using variational methods, we prove that there is a positive ground state solution for the aforementioned equation concentrating at a global minimum of

V

V

in the semi-classical limit, and then we found that this solution satisfies the property of exponential decay. Finally, the multiplicity and concentration behavior of positive solutions for the aforementioned problem is investigated by the Ljusternik-Schnirelmann theory. Our article improves and extends some existing results in several directions.
Efficiency of early selection for growth and wood quality traits of slash pine in three progeny trials in southern China
Authors: Lai Meng , Dong Leiming , Zhang Lu , Liu Siyu , Wen Jing , Yi Min 
Published: February 2023

Abstract
A firm understanding of the early selection efficiency of ring width and wood quality traits is a prerequisite for breeding of higher growth rates and wood quality of slash pine (Pinus elliottii Engelm.). To accomplish effective early selection for the studied traits, wood core samples were collected from 360 trees of 20 open-pollinated families from three slash pine rotation-aged (harvest age) genetic trials. Wood cores were measured by SilviScan, and the annual patterning, heritability, age-age genetic correlation and efficiency of early selection for ring width, modulus of elasticity (MOE), microfibril angle (MFA) and wood density for early to reference age (age 27) were investigated. The greatest annual ring width was observed at age 4, and this trait decreased gradually toward the bark. Different radial trends were found for MOE and MFA. Wood density was lowest near the pith and then increased steadily with age. Overall, heritability was moderate to high for all area-weighted wood quality traits. Very high age-age genetic correlation values were observed for all traits researched. Estimates of efficiency for early selection indicated that the optimal age of early selection for ring width was 9–12 years, while that for area-weighted MOE, MFA and wood density was 7–8 years.
Intelligent gloves: An IT intervention for deaf-mute people
Authors: Babour Amal , Bitar Hind , Alzamzami Ohoud , Alahmadi Dimah , Barsheed Amal , Alghamdi Amal , Almshjary Hanadi 
Published: February 2023

Abstract
Deaf-mute people have much potential to contribute to society. However, communication between deaf-mutes and non-deaf-mutes is a problem that isolates deaf-mutes from society and prevents them from interacting with others. In this study, an information technology intervention, intelligent gloves (IG), a prototype of a two-way communication glove, was developed to facilitate communication between deaf-mutes and non-deaf-mutes. IG consists of a pair of gloves, flex sensors, an Arduino nano, a screen with a built-in microphone, a speaker, and an SD card module. To facilitate communication from the deaf-mutes to the non-deaf-mutes, the flex sensors sense the hand gestures and connected wires, and then transmit the hand movement signals to the Arduino nano where they are translated into words and sentences. The output is displayed on a small screen attached to the gloves, and it is also issued as voice from the speakers attached to the gloves. For communication from the non-deaf-mutes to the deaf-mute, the built-in microphone in the screen senses the voice, which is then transmitted to the Arduino nano to translate it to sentences and sign language, which are displayed on the screen using a 3D avatar. A unit testing of IG has shown that it performed as expected without errors. In addition, IG was tested on ten participants, and it has been shown to be both usable and accepted by the target users.
Metabolic resuscitation therapy in critically ill patients with sepsis and septic shock: A pilot prospective randomized controlled trial
Authors: Feng Fang , Yang Huyong , Yang Weiwei , Chen Yu 
Published: February 2023

Abstract
The main purpose of our research was to further clarify the effectiveness and potential pathophysiological principles of metabolic resuscitation therapy in critically ill patients with sepsis and septic shock. We found that metabolic resuscitation therapy is beneficial for patients with sepsis and septic shock, shortening the length of intensive care unit (ICU) stay, reducing the duration of vasopressor use, and reducing the ICU mortality rate of patients with sepsis and septic shock, but it does not reduce the hospital mortality rate.
Lycopene ameliorates locomotor activity and urinary frequency induced by pelvic venous congestion in rats
Authors: Zhao Jinchai , Chen Wei , Liu Jian 
Published: February 2023

Abstract
Decreased locomotor activity and altered urinary frequency are induced by bilateral common iliac vein ligation in rats. As a carotenoid, lycopene has a strong anti-oxidative function. This research investigated the function of lycopene in the pelvic venous congestion (PC) rat model and the underlying molecular mechanism. Lycopene and olive oil were administered intragastrically on a daily basis for 4 weeks after successful modeling. Locomotor activity, voiding behavior, and continuous cystometry were analyzed. The levels of 8-hydroxy-2′-deoxyguanosine (8-OHdG), nitrate and nitrite (NO
x
), and creatinine in the urine were measured. Gene expression in the bladder wall was analyzed by quantitative reverse transcription polymerase chain reaction, enzyme-linked immunosorbent assay, and Western blot. Locomotor activity, single voided volume, the interval between the bladder contractions, and urinary NO
x
/cre ratio were all decreased in rats with PC, while the frequency of urination, urinary 8-OHdG/cre ratio, inflammatory responses, and nuclear factor-κB (NF-κB) signal activity were all increased. Lycopene treatment increased locomotor activity, decreased frequency of urination, elevated urinary NO
x
level, and decreased urinary 8-OHdG level in the PC rat model. Lycopene also inhibited PC-enhanced pro-inflammatory mediator expression and NF‐κB signaling pathway activity. In conclusion, lycopene treatment ameliorates PC-induced phenotypes and shows an anti-inflammatory effect in the PC rat model.
Applying solution of spray polyurea elastomer in asphalt binder: Feasibility analysis and DSR study based on the MSCR and LAS tests
Authors: Sun Xiaolong , Yuan Zhengbing , Huang Zhenying , Xu Qin , Zhu Yongqiang , Xu Xinquan , Yuan Junshen , Liu Zhisheng , Zhang Yikang , Chen Qian , Ng Alex Hay-Man 
Published: February 2023

Abstract
The polyurea elastomer (PUA) powder modifier was prepared by the method of spraying–initial crushing–fine grinding, and then, the PUA-modified asphalt was produced. The typical functional structure of PUA was identified and characterized. The apparent viscosity of PUA-modified asphalt was tested at different temperatures. The impact of particle size and content of PUA on creep and recovery properties of asphalt at high temperature was investigated through the multiple stress creep recovery test. The mesothermal fatigue behavior of PUA-modified asphalt was evaluated by means of time sweep and linear amplitude sweep. Results indicated that the high elastic properties of PUA materials might depend on the spherical structure inside PUA material. The diameter of functional structure was around 20 µm and presented as 3D ball structure. The increase in PUA particle size would lead to the increase in cracks and folds in the bonding surface PUA modifier could improve by about 50% of the apparent viscosity significantly. Furthermore, PUA modifier could promote the high-temperature rutting resistance and middle-temperature fatigue property of asphalt. The improving effect on R could reach almost 28% and the 0.075 mm could be the best application size of PUA.
Etiology and Pathogenesis of Postoperative Cognitive Dysfunction (Review)
Authors: Neimark M. I. , Shmelev V. V. , Rakhmonov A. A. , Titova Z. A. 
Published: February 2023

Impairment of higher mental functions can complicate the course of the postoperative period even after short and minimally invasive, including laparoscopic, surgical procedures. Postoperative cognitive dysfunction significantly challenges patients’ quality of life, negating real success of surgical intervention and anesthetic support. In some cases, early postoperative cognitive dysfunction may be one of the main predictors of persistent cognitive impairment.The purpose of the review. To contemplate etiology, pathogenesis and the current perspective of postoperative cognitive dysfunction.We analyzed 96 publications in various databases (PubMed, Medline, RSCI and others), including 67 papers published over the past 5 years.The review provides an overview of current definitions and classification of postoperative cognitive dysfunction, data on the prevalence, polyethyology and risk factors, potential impact of the type of anesthesia and surgical intervention on the development of postoperative cognitive dysfunction. Various pathogenetic mechanisms of higher mental functions impairment alongside with available effective pharmacotherapies to correct them were considered.Conclusion. Numerous adverse factors of the perioperative period, such as neurotoxic effects of general anesthetics, neuroinflammation in response to operational stress and surgical trauma, impaired autoregulation of the cerebral blood flow, imperfect oxygen homeostasis, interactions of neurotransmitter, etc., can potentially cause postoperative cognitive dysfunction. Further deeper insights into etiology and pathogenesis of early postoperative cognitive dysfunction are relevant and necessary to improve prevention strategies and identify most effective pharmacotherapies to correct such disorders.
Predictors of Clinical Efficacy of Cytokine Hemoadsorption in COVID-19 (Clinical Trial)
Authors: Ratnikov V. A. , Sheglov A. N. , Abramovskiy S. V. , Simutis I. S. , Danilov M. S. , Ivanova G. G. , Syrovatskii A. A. 
Published: February 2023

Materials and methods. This study analyzed the results of treatment of 62 patients with severe COVID-19 in the intensive care unit using selective hemoadsorption of cytokines. All patients with severe COVID-19 were admitted to the intensive care unit within 14 days from the disease onset were subdivided into two groups. Group 1 patients (n=32) received on a top of standard treatment the hemoperfusion (HP) procedure for 4 hours, for 2–3 days in a row, using a cytokine sorption column composed of mesoporous styrene-divinilbenzen copolymer matrix. Group 2 patients were not subjected to extracorporeal blood purification. All patients received IL-6 inhibitors at a baseline in accordance to the temporary guidelines. We evaluated factors of unfavorable outcomes by analyzing changes in biochemical markers of systemic inflammatory response and mortality rates in patients of both groups.Results. Initiation of HP later than 10 days from NCI onset (P < 0.001), length of stay in the ICU, extent of lung damage (P = 0.036) and the SOFA (Sequential Organ Failure Assessment) score (P = 0.009) were the most powerful predictors of unfavorable outcome. Levels of systemic inflammatory response markers (interleukin- 6, CRP, D-dimer) in both groups did not significantly affect the survival rates and length of hospital stay (P > 0.05). HP group demonstrated better survival (P < 0.05). Mean hospital stay was 31 and 27 days, ICU stay — 11 and 8 days for Groups 1 and 2, respectively (P < 0.05).Conclusion. Treatment of severe COVID-19 patients with HP using novel domestic hemosorbent composed of styrene-divinilbenzen copolymer matrix resulted in decrease in CRP levels on the first day after application and, with early onset, contributed to a significant increase in survival and decreased hospital and ICU stay. Additional studies are warranted to clarify the optimal timing of the initiation of HP in severe COVID-19 patients.
Achieving and Maintaining Effective Plasma Concentration of Lithium After Oral Administration
Authors: Makarevich D. G. , Grebenchikov O. A. , Yadgarov M. Ya. , Berikashvili L. B. , Kadantseva K. K. , Likhvantsev V. V. 
Published: February 2023

The aim of the study. To study the achievability and contingency to maintain an effective plasma lithium concentration in the perioperative period in patients undergoing carotid endarterectomy (CEAE) with oral intake of lithium carbonate pills.Materials and methods. It was a prospective study, as a preparatory stage of the multicenter «BINOS» (NCT05126238) RCT. The sample included 15 patients undergoing elective CEAE. In the course of this study, patients were administered oral lithium carbonate, 900 mg per day during 4 perioperative days: two days before the procedure, in the day of surgery and in the 1st postoperative day. Plasma lithium concentration was monitored every 24 hours during all 4 days from the onset of treatment.Results. Increased plasma lithium concentrations were found in blood samples taken at 48 hours (0.68 mmol/l [0.53–0.84, P = 0.004) and 72 hours (0.68 mmol/l [0.62–0.90, P < 0.001), as compared with the initial values (0.14 mmol/l [0.11–0.17).While during the period between 48 and 72 hours from the onset of treatment the plasma lithium concentration remained in the therapeutic range (0.4–1.2 mmol/l) in 100% of patients.Conclusion. Oral intake of lithium carbonate pills at a dose of 900 mg/day during 2 preoperative days provided an effective and safe plasma lithium concentration in 100% of patients enrolled in the study.
Assessment of Anthropometric Data of Children Died at Perinatal Period
Authors: Moiseeva Karina E. , Ivanov Dmitry O. , Yur’ev Vadim K. , Berezkina Elena N. , Shevtsova Kseniya G. , Alekseeva Anna V. , Kharbedia Shalva D. 
Published: February 2023

Background. Despite the decrease in fetoinfantile losses, the levels of perinatal mortality and stillbirth remain quite high. One of the medical criteria for viability is the anthropometric indicators of the child, therefore, their relevant medical and statistical assessment may allow us to establish potential opportunities for reducing the loss of viable children at perinatal period.Objective. The aim of the study is to assess anthropometric data of children died at perinatal period.Methods. We have analyzed 277 cases of children deaths at ante- and intranatal periods and 197 cases of newborns deaths during first 7 days of life. Assessment of anthropometric data of children died at perinatal period was presented via the method of sigmal deviations and the centile method.Results. Anthropometric data of premature infants died at perinatal period in 90–94% of cases corresponded to the physical development for children of this gestational age. Anthropometric data of full-term children died during the first 168 hours of life, in 70.0% of cases, corresponded to 3–6 corridors of physical development (P10–P90), in 20.0% of cases — 7–8 corridors. 58.3% of full-term children died at perinatal period have harmonious development which significantly exceeds the proportion of children with sharply disharmonious development (19.5%) and with disharmonious development (22.2%). 79.0% of all neonatal deaths occur in the first 72 hours of life (for the early neonatal period), while losses on the first day account for 54.0% of all deaths in children during the first week.Conclusion. This study has shown that the anthropometric data of children died at perinatal period significantly corresponded to the standard indicators established for children of this gestation age.
Chronic Diarrhea as a Debut Manifestation of Crohn’s Disease in Infant: Clinical Case
Authors: Konovalova Anna M. , Pechkurov Dmitry V. , Tyazheva Alena A. 
Published: February 2023

Background. Chronic diarrhea can be a symptom of a wide variety of diseases, either of which requires special therapy approaches. The diagnosis of rare causes of chronic diarrhea is especially difficulty as it may be associated with inflammatory bowel disease (IBD) with very early (under 1 year of age) debut.Clinical case description. Boy E. had chronic diarrhea manifested on the first year of life. Ulcerative colitis was diagnosed at the age of 1.5 years, then the diagnosis was changed to Crohn’s disease at the age of 2.5 years. The results of 6-years-follow-up of the patient were presented, as well as analysis of diagnosis and treatment difficulties was carried out.Conclusion. The clinical case of Crohn’s disease with diarrhea as the leading clinical manifestation at the disease onset is described. Sequential diagnostic search allowed us to establish the diagnosis of IBD and to exclude other causes of chronic diarrhea that determined the correct therapeutic strategy.
Abdominal aortic aneurysm screening: are those at high-risk being overlooked?
Authors: Patil Sangram D. , Pillay Willy 
Published: February 2023

An abdominal aortic aneurysm (AAA) is defined as enlargement of an abdominal aorta with a diameter of 3.0 cm or larger in the anteroposterior or transverse plane. In order to diagnose and treat this disease early, clinical trials were conducted to evaluate the benefits of ultrasound screening for AAA. There is enough good evidence to recommend AAA population ultrasound scan screening for men over 65 years old. Prevalence rates for AAA amongst males at age 65 detected by screening appear to be decreasing, however AAA screening continues to be cost effective. There has been emerging evidence suggesting a strong link between family history and development of AAA. The prevalence of AAA amongst family members has been higher when compared to general population. This high prevalence of AAA in the first-degree relatives provide a strong argument for aggressive approach to screening of this specific cohort. After the latest literature review, there have been no data from a single randomised clinical trial or large nonrandomised studies published with ‘targeted USS screening’ with regards to family history of AAA. Ultrasound screening for the first-degree relatives, both male and female, of patients with AAA appears to be feasible and cost effective. A pilot study to determine the prevalence of familial AAA amongst probands and the prevalence amongst first degree relatives should identify the unmet need for AAA screening for this cohort and quantify the resources required for a sustainable screening programme.
Comparison of open reduction internal fixation by lateral extensile approach versus conservative management in sanders type 2 and 3 calcaneum fractures: a prospective, two-arm, parallel group study
Authors: Tathe Pankaj V. , Garg Rohit , Sakharkar Nilesh S. , Adewar Aniket , Mithal Ayush , Atilkar Akshay J. 
Published: February 2023

Background: Calcaneum bone is the most common tarsal bone to get fractured. It accounts for 50-60% of all fractured tarsal bones. Calcaneum fractures are always debilitating and are challenging and cumbersome to treat. There is a paucity of Indian studies to assess the comparative treatment outcomes of calcaneal fractures treated by non-operative conservative procedure and open reduction internal fixation by lateral extensile approach.
Methods: Adult patients with closed intra-articular calcaneum fractures of Sanders type 2 and 3 were enrolled. Patients managed by cast application (non-operative) or open reduction internal fixation (operative) were separated into two groups. The VAS score for pain, range of motion, radiological angles (Bohler’s and Crucial angle of Gissane) and parameters, functional scores American orthopedic foot and ankle society and Maryland foot score were evaluated sixth month and 1-year post-intervention and compared between the study groups. Descriptive statistics were used for statistical analysis.
Results: 29 patients managed with open reduction internal fixation (N=15) or cast application (N=14) were enrolled. The mean age of patients was 39.54±7.81 years, 22 being males and 7 females. Mean VAS score was significantly lower in the plating group at sixth month (4.31+0.69 vs. 5.01+0.66, p<0.05) but not significant at 1 year (1.25+1.09 vs. 1.86+0.77, p<0.05). Range of movements at the ankle and subtalar joints were higher in the operative group. Mean Bohler’s angle was significantly higher and Gissane’s angle lower in the operative group (p<0.05). Significantly higher AOFAS and Maryland scores were noted in the operative group (p<0.05). Subtalar arthritis with malunion was more common in the non-operative group.
Conclusions: Operative open reduction and internal fixation methods were found to be significantly better than the conservative management of calcaneus fracture based on clinical, radiological and functional outcomes. Results are most favourable if wound complications are minimized.