bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bringing Compiling Databases to RISC Architectures
Authors: Gruber Ferdinand , Bandle Maximilian , Engelke Alexis , Neumann Thomas , Giceva Jana 
Published: April 2023

Current hardware development greatly influences the design decisions of modern database systems. For many modern performance-focused database systems, query compilation emerged as an integral part and different approaches for code generation evolved, making use of standard compilers, general-purpose compiler libraries, or domain-specific code generators. However, development primarily focused on the dominating x86-64 server architecture; but neglected current hardware developments towards other CPU architectures like ARM and other RISC architectures.
Therefore, we explore the design space of code generation in database systems considering a variety of state-of-the-art compilation approaches with a set of qualitative and quantitative metrics. Based on our findings, we have developed a new code generator called FireARM for AArch64-based systems in our database system, Umbra. We identify general as well as architecture-specific challenges for custom code generation in databases and provide potential solutions to abstract or handle them.
Furthermore, we present an extensive evaluation of different compilation approaches in Umbra on a wide variety of x86-64 and ARM machines. In particular, we compare quantitative performance characteristics such as compilation latency and query throughput.
Our results show that using standard languages and compiler infrastructures reduces the barrier to employing query compilation and allows for high performance on big data sets, while domain-specific code generators can achieve a significantly lower compilation overhead and allow for better targeting of new architectures.
Efficient Black-Box Checking of Snapshot Isolation in Databases
Authors: Huang Kaile , Liu Si , Chen Zhenge , Wei Hengfeng , Basin David , Li Haixiang , Pan Anqun 
Published: April 2023

Snapshot isolation (SI) is a prevalent weak isolation level that avoids the performance penalty imposed by serializability and simultaneously prevents various undesired data anomalies. Nevertheless, SI anomalies have recently been found in production cloud databases that claim to provide the SI guarantee. Given the complex and often unavailable internals of such databases, a black-box SI checker is highly desirable.
In this paper we present PolySI, a black-box checker that efficiently checks SI and provides understandable counterexamples upon detecting violations. PolySI builds on a characterization of SI using generalized polygraphs (GPs), for which we establish its soundness and completeness. PolySI employs an SMT solver and also accelerates SMT solving by utilizing a compact constraint encoding of GPs and domain-specific optimizations for pruning constraints. As our extensive assessment demonstrates, PolySI successfully reproduces all of 2477 known SI anomalies, detects novel SI violations in three production cloud databases, identifies their causes, outperforms the state-of-the-art black-box checkers under a wide range of workloads, and can scale up to large workloads.
Flare: A Fast, Secure, and Memory-Efficient Distributed Analytics Framework
Authors: Li Xiang , Li Fabing , Gao Mingyu 
Published: April 2023

As big data processing in the cloud becomes prevalent today, data privacy on such public platforms raises critical concerns. Hardware-based trusted execution environments (TEEs) provide promising and practical platforms for low-cost privacy-preserving data processing. However, using TEEs to enhance the security of data analytics frameworks like Apache Spark involves challenging issues when separating various framework components into trusted and untrusted domains, demanding meticulous considerations for programmability, performance, and security.
Based on Intel SGX, we build Flare, a fast, secure, and memory-efficient data analytics framework with a familiar user programming interface and useful functionalities similar to Apache Spark. Flare ensures confidentiality and integrity by keeping sensitive data and computations encrypted and authenticated. It also supports oblivious processing to protect against access pattern side channels. The main innovations of Flare include a novel abstraction paradigm of shadow operators and shadow tasks to minimize trusted components and reduce domain switch overheads, memory-efficient data processing with proper granularities for different operators, and adaptive parallelization based on memory allocation intensity for better scalability. Flare outperforms the state-of-the-art secure framework by 3.0× to 176.1×, and is also 2.8× to 28.3× faster than a monolithic libOS-based integration approach.
Using Deadlifts as a Postactivation Performance Enhancement Strategy in Warm-ups in Football
Authors: Abade Eduardo , Brito João , Gonçalves Bruno , Saura Luís , Coutinho Diogo , Sampaio Jaime 
Published: April 2023

Abstract
Abade, E, Brito, J, Gonçalves, B, Saura, L, Coutinho, D, and Sampaio, J. Using deadlifts as a postactivation performance enhancement strategy in warm-ups in football. J Strength Cond Res XX(X): 000–000, 2022—Postactivation performance enhancement activities may be relevant warm-up strategies aiming to improve subsequent physical performance. The purpose of the current study was to investigate the effects of adding barbell deadlift or hex-bar deadlift exercises to current warm-up routines on running and jumping performances in football players. Ten highly trained male football players participated in the study during the competitive phase of the season. All players performed 3 protocols in the same week: a standard warm-up that included players' regular routines and 2 other protocols with the addition of barbell or hex-bar deadlift, after the end of the warm-up (3 sets of 3 reps, progressing set by set from 60% to 85% repetition maximum). All protocols had the same time interval between pretest (immediately after the warm-up) and posttest (15 minutes after the warm-up). Vertical jumping (countermovement jump [CMJ]; Abalakov jump [AJ]) and running performances (505 test) were impaired 15 minutes after the standard warm-up (CMJ: −6.7 ± 4.2%; AJ: −8.1 ± 8.4%; and 505 time: 1.4 ± 2.5%). For warm-up with the addition of barbell deadlift, vertical jump increased by 4.3 ± 5.6% (Cohen's d

unb
: 0.23 [0.02–0.47]) and 505 time decreased by −5.9 ± 3.6% (Cohen's d

unb
: 0.97 [−1.68 to −0.43]). The warm-up with hex-bar deadlift led to trivial changes for CMJ and AJ, but 505 time decrease by −2.7 ± 2.6% (Cohen's d

unb
: −0.53 [−1.01 to −0.13]). The deadlift exercise can be added to warm-up routines to maintain or even enhance acute physical performance. However, coaches and practitioners should be aware that performance enhancements resultant from deadlift may vary according to individual physical profiles.
Ana Ozores y santa Teresa de Jesús: «el coloquio de dos almas a través de tres siglos». Consideraciones acerca de la recepción de la autobiografía teresiana en La Regenta
Authors: García Sánchez Laura 
Published: April 2023

El presente estudio trata de establecer, a partir de los paralelismos biográficos y de las referencias intertextuales, la influencia de Teresa de Cepeda y Ahumada en la construcción psicológica de Ana Ozores. Dicha influencia, patente textualmente a raíz de la asimilación del Libro de la Vida en la segunda parte de la obra, parte de la existencia de unos antecedentes familiares semejantes, de las lecturas de infancia y adolescencia, de la reivindicación de la creación literaria femenina o de una concepción religiosa cercana al misticismo. Estas circunstancias vitales y culturales se erigen como los puntos de intersección entre ambas mujeres.Palabras clave: Ana Ozores, santa Teresa, infancia, lecturas, misticismo.Ana Ozores and santa Teresa de Jesús: «el coloquio de dos almas a través de tres siglos». Considerations about the teresian autobiography’s reception in La RegentaAbstract:This study aims to demonstrate the influence of Teresa de Cepeda y Ahumada in the development of the psicological profile of Ana Ozores, using the similarities in their biographies and several intertextual references. Such influence, evident in the text since the reading of Libro de la Vida by Ana in the second part of the book, starts from the existence of a similar family history, the childhood and adolescence readings, the claim of literary female creation or a religious conception close to mysticism. These vital and cultural circumstances stand as the points of intersection between the two women.Key words: Ana Ozores, santa Teresa, chilhood, readings, mysticism.
El pacto epistolar en relación a la auto-ficción en Correspondencia privada, de Esther Tusquets
Authors: Toribio Álvarez Andrea 
Published: April 2023

En este trabajo, analizaremos el vínculo entre el artificio epistolar, bajo la óptica del cuento, y la ficción autobiográfica en Correspondencia privada (2001), de la editora y escritora catalana Esther Tusquets. Así mismo, estudiaremos la construcción de los distintos destinatarios o interlocutores a los que se dirige en dicha obra y los múltiples procesos de reescritura de su proyecto literario que afectan a la misma. Abordaremos, de forma paralela, la conquista del espacio de lo privado por parte de la escritora desde su condición femenina y desde las categorías «experiencia» y «memoria».Palabras clave: Modelo epistolar, Ficción autobiográfica, Cuento, Esther Tusquets.The epistolary pact in relation to self-fiction in Correspondencia Privada, by Esther TusquetsAbstract: This research will analyse the relation between the epistolary art, throghout the tale genre, and the autobiographical fiction in Correspondencia privada (2001), of the catalan editor and writer Esther Tusquets. Furthermore, it will study the setting of the different addressees or speakers to whom she is writting for and the numerous procedures of rewriting from her literary project that affect this book. It will consider thus the re-appropiation of the private space by the author from the female condition and the spheres of «experience» and «memory».Key words: Epistolary art, Autobiographical fiction, Tale genre, Esther Tusquets.
Improving the Quality of Written Discharge Instructions: A Multisite Collaborative Project
Authors: Desai Arti D. , Tolpadi Anagha , Parast Layla , Esporas Megan , Britto Maria T. , Gidengil Courtney , Wilson Karen , Bardach Naomi S. , Basco William T. , Brittan Mark S. , Johnson David P. , Wood Kelly E. , Yung Steven , Dawley Erin , Fiore Darren , Gregoire LiseAnne , Hodo Laura N. , Leggett Brett , Piazza Kirstin , Sartori Laura F. , Weber Danielle E. , Mangione-Smith Rita 
Published: April 2023

BACKGROUND AND OBJECTIVES
Written discharge instructions help to bridge hospital-to-home transitions for patients and families, though substantial variation in discharge instruction quality exists. We aimed to assess the association between participation in an Institute for Healthcare Improvement Virtual Breakthrough Series collaborative and the quality of pediatric written discharge instructions across 8 US hospitals.

METHODS
We conducted a multicenter, interrupted time-series analysis of a medical records-based quality measure focused on written discharge instruction content (0–100 scale, higher scores reflect better quality). Data were from random samples of pediatric patients (N = 5739) discharged from participating hospitals between September 2015 and August 2016, and between December 2017 and January 2020. These periods consisted of 3 phases: 1. a 14-month precollaborative phase; 2. a 12-month quality improvement collaborative phase when hospitals implemented multiple rapid cycle tests of change and shared improvement strategies; and 3. a 12-month postcollaborative phase. Interrupted time-series models assessed the association between study phase and measure performance over time, stratified by baseline hospital performance, adjusting for seasonality and hospital fixed effects.

RESULTS
Among hospitals with high baseline performance, measure scores increased during the quality improvement collaborative phase beyond the expected precollaborative trend (+0.7 points/month; 95% confidence interval, 0.4–1.0; P &lt; .001). Among hospitals with low baseline performance, measure scores increased but at a lower rate than the expected precollaborative trend (−0.5 points/month; 95% confidence interval, −0.8 to −0.2; P &lt; .01).

CONCLUSIONS
Participation in this 8-hospital Institute for Healthcare Improvement Virtual Breakthrough Series collaborative was associated with improvement in the quality of written discharge instructions beyond precollaborative trends only for hospitals with high baseline performance.
Las fronteras en Colombia: su origen, evolución, pérdida e importancia en las Relaciones Internacionales
Authors: Cano Blandon Rodolfo 
Published: April 2023

La política exterior colombiana es reciente. La configuración territorial del país en 1819, su unión a Venezuela y Ecuador en la Gran Colombia y su posterior disolución en 1831 obligaron a la naciente república a constituir relaciones con los demás Estados. A partir de las primeras constituciones promulgadas desde 1810 las relaciones internacionales quedaron plasmadas en las consecutivas cartas políticas. No obstante, a pesar de haberse escrito dieciséis constituciones políticas durante cerca de doscientos años de vida republicana y de haber considerado la política exterior como un elemento fundamental dentro de la evolución y maduración del Estado colombiano, las fronteras territoriales y marítimas de Colombia estuvieron sumidas en el atraso y en el olvido estatal, y las políticas e inversiones en dichos territorios fueron deficientes.
Se estima que Colombia ha cedido gran parte de su territorio continental y marítimo a países como Venezuela, Brasil, Perú, Ecuador, Panamá y en el mar Caribe con Venezuela y Nicaragua. La cesión del territorio confirma la falta de visión política, marítima y prospectiva del Estado colombiano, respecto a territorios de suma importancia para la configuración del país. Por esta y otras razones el presente artículo desarrolla el tema de los territorios fronterizos colombianos, su nacimiento con el uti possidetis iuris de 1810, su sufrida y malograda negociación con los países vecinos, su evolución y las cesiones territoriales y marítimas durante los últimos dos siglos de vida republicana[1].

[1] El presente artículo sintetiza la tesis doctoral Reconfiguración territorial en Colombia: el papel del Estado y la diplomacia en las fronteras (1830-2012), realizada en el Doctorado en Estudios Políticos de la Universidad Externado de Colom­bia. La investigación fue elaborada entre 2014 y 2020.
MHC polymorphism in the immune system
Authors: Pinatih Komang Januartha Putra , Supadmanaba I Gede Putu , Wihandani Desak Made 
Published: April 2023

An antigen will be able to stimulate an immune response if the antigen has been presented and recognized by T-cells. Major Histocompatibility Complex (MHC) molecules are molecules that will recognize and present the peptides of the antigen. In humans, two classes of MHC are known to carry out this role, namely Class-I MHC and Class-II MHC, while Class-III MHC has a function that is not directly related to peptide binding. The genes that code for MHC molecules are so polymorphic that each individual is certain to have a different allele (heterozygous). In Class-I MHC, only the α-chain is polymorphic while in Class-II MHC both α and β-chains are polymorphic. MHC polymorphism will affect (1) the ability to create immune responses including antibody production, (2) resistance or susceptibility to infectious diseases, and (3) resistance or susceptibility to autoimmune and allergic diseases. That is why MHC is so polymorphic. The immune system has to fight many different pathogens. By having many different MHC molecules, one can present widely different antigens and can spur an effective immune response.
No Effect of the p.Arg230His Variant Of The VCL Protein on the Course of the Hypertrophic Cardiomyopathy In Russian Family Carrying The p.Gln1233Ter Pathogenic Variant In The MYBPC3 Gene
Authors: Filatova E. V. , Krylova N. S. , Klass A. L. , Kovalevskaya E. A. , Maslova M. Yu. , Shadrina M. I. , Poteshkina N. G. , Slominsky P. A. 
Published: April 2023

Aim To determine specific clinical characteristics caused by a combination of the rs397516037 pathogenic variant in the myosin-binding protein C (MTBPC3) and the rs749628307 polymorphic variant in the vinculin (VCL) gene in a Russian family of carriers and to evaluate the contribution of the rs749628307 polymorphic variant in the VCL gene to the development of hypertrophic cardiomyopathy (HCMP).Material and methods The family under study included one healthy person and 3 patients with HCMP. A targeted analysis of proband’s exome was performed. A structural alignment for both forms of the VCL protein, the canonical form and the form with p.Arg230His substitution, was performed.Results The pathogenic rs397516037 variant and the potentially pathogenic rs749628307 variant were detected in the proband and several family members. A possibly damaging variant rs749628307 was detected in the proband and several family members evaluated in this study. The structural alignment confirmed that the rs749628307 variant did not alter the protein structure significantly and could not cause an impairment or loss of the protein function.Conclusion This study demonstrated that apparently the rs749628307 variant in the VCL gene does not affect the protein structure in a pathogenetically significant way, neither does it affect the severity and form of the clinical manifestations of HCMP; therefore, it cannot be considered as pathogenic.
Endothelial Dysfunction in Patients With Takotsubo Syndrome and its Role in Acute and Long Terms Of the Disease
Authors: Evdokimov D. S. , Feoktistova V. S. , Boldueva S. A. , Ermolov S. Yu. , Gaykovaya L. B. 
Published: April 2023

Aim To evaluate the endothelial function using an Endo-PAT2000 instrument before and after mental stress tests in patients with Tacotsubo syndrome (TS) during acute and long-term periods and to compare the obtained results with laboratory markers of endothelial dysfunction (ED).Material and methods This study included 45 patients with TS (mean age, 63.5±13.7 years) and 40 healthy volunteers (control group, CG). All patients of the main group during the acute period (first 7–14 days) and long-term period (at 1 and 2 years), as well as CG subjects, underwent evaluation of the endothelial function with an Endo-PAT 2000 instrument, and the reactive hyperemia index (RHI) was determined before and after mental stress tests. Also, concentrations of endothelin 1 (ET-1) and numbers of circulating endothelial cells (CEC) were measured after a two-year follow-up of TS patients.Results During the acute period of disease, all TS patients (n=45) had ED: RHI was below the threshold level of 1.67; furthermore, 42 (93.3 %) patients retained a lower RHI following mental stress. At one year (n=40), 16 (40%) patients showed ED at rest along with a significantly increased mean RHI. Mental stress produced at one year was associated with ED in 28 (70 %) TS patients. At two years (n=44), resting RHI was lower than normal in 19 (43.2 %) patients. Mental stress tests performed at two years were associated with ED in 29 (65.9 %) patients (RHI ≤1.67). Only 10% of CG subjects had a lower-than-normal RHI, which was significantly less than in the main group of TS patients during the acute and long-term periods (p<0.05). Mean values of laboratory markers for ED also were significantly different between TS patients during the long-term period of disease (n=41) and CG subjects (n=40; p<0.01).Conclusion During acute and long-term periods of disease, most of TS patients had impaired vascular reactivity both at rest and during mental stress. The laboratory markers of ED, ET-1 and CEC can be used in clinical practice for evaluation of the risk for TS.
Evolución del régimen colombiano de servicios de radiocomunicaciones por satélite
Authors: Valderrama Rojas Carmen Ligia , González Cárdenas Geusseppe 
Published: April 2023

Las tecnologías han evolucionado rápidamente en torno a la mejora continua de la transmisión de información. Esta evolución ha impactado la tecnología satelital tradicionalmente empleada para llevar conectividad y servicios de comunicaciones a lugares remotos y lejanos, pero que se veía limitada por algunas de sus características técnicas, como por ejemplo, capacidad y latencia, así como, por su alto costo. No obstante, la optimización técnica de las capacidades que nos ofrecen actualmente los satélites de comunicaciones ha generado que los países se enfoquen en aprovechar su potencial como elemento de desarrollo y crecimiento económico. En el caso colombiano, resultan de total utilidad para llevar conectividad a zonas rurales apartadas y de difícil acceso en las que el despliegue de las tecnologías terrestres tradiciones se dificulta debido a las diversas características orográficas del territorio.
Teniendo en cuenta estos antecedentes, el Ministerio de Tecnologías de la Información y las Comunicaciones (MINTIC) a través de la Resolución MINTIC 376 de 2022, impulsó la modernización del sector actualizando el marco normativo que había sido expedido mediante la Resolución MINTIC 106 de 2013, conforme a las mejores prácticas internacionales, así como también de las experiencias y evolución propia de nuestro país. Con este fin, flexibilizó los procedimientos para el otorgamiento del permiso para uso o explotación del espectro radioeléctrico e implementó criterios diferenciales para fijar el monto de la contraprestación. Con estas medidas se busca generar un entorno que promueva la inversión, y beneficie a todos los habitantes de Colombia con un mercado más competitivo, con más actores y por consiguiente con la posibilidad de encontrar mejores ofertas de servicios de telecomunicaciones. En este orden de ideas, resulta claro que el país requería un Régimen Satelital moderno que reconociera y, que también, propiciara las nuevas dinámicas de las comunicaciones satelitales para maximizar los beneficios disponibles en el entorno tecnológico de la industria satelital.
Ethical problems in the development of artificial intelligence technologies in healthcare
Authors: Gusev A. V. , Sharova D. E. 
Published: April 2023

The development and implementation of software based on artificial intelligence (AI) technologies is one of the main directions of the digital transformation in healthcare. The global market for AI systems in medicine as well as re­search in this area are the main industry drivers. At the same time there is a growing concern in the medical profes­sional community about the safety and effectiveness of AI-based software when it is put into practice. Responsibility issues come to the fore when discussing the pace of development of the AI industry. The aim of the work was to analyze the existing ethical problems of AI implementation in healthcare and to formulate priorities for overcoming them.