bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intraprocedural Cortisol Measurement Increases Adrenal Vein Cannulation Success Rate in Primary Aldosteronism: A Systematic Review and Meta-analysis
Authors: Zhou Yaqiong , Zhang Huamin , Luo Jie , Hou Jixin , Xue Qiang , Wang Xiaohan , Guo Hui , Wang Xinquan , Wang Peijian 
Published: September 2023

Abstract

BACKGROUND
This study aimed to explore the effectiveness of intraprocedural cortisol measurement (IPCM) for the technical success rates of bilateral adrenal vein, right adrenal vein (RAV), and left adrenal vein (LAV) cannulation during adrenal vein sampling (AVS).

METHODS
Systematic searches of PubMed, Embase, Cochrane Library, and ClinicalTrials.gov were performed from database inception to May 10, 2023, without any restrictions. We estimated the overall effect estimates of outcomes using the Mantel–Haenszel random-effects model. We conducted subgroup analyses, meta-regression, and sensitivity analysis to explore the possible sources of between-study heterogeneity.

RESULTS
In total, 3,485 patients from 11 studies (three prospective and eight retrospective) were enrolled. Bilateral selectivity in patients who underwent IPCM during AVS was significantly higher than that in patients who underwent a routine AVS procedure (84% vs. 64%, RR 1.42, 95% confidence interval [CI]: 1.27–1.59, P &lt; 0.01), with significant heterogeneity (I2 = 68%). A 42% relative risk reduction in the failure rate of bilateral adrenal vein cannulation was found in the IPCM group. Moreover, pooled analysis showed a significant increase in the success rates of RAV cannulation (84% vs. 72%, RR 1.21, 95% CI 1.12–1.31, P &lt; 0.01, I2 = 33%) and LAV cannulation (89% vs. 84%, RR 1.05, 95% CI 1.02–1.08, P &lt; 0.01, I2 = 4%) when IPCM was implemented during the AVS procedure compared to the routine AVS procedure.

CONCLUSIONS
An IPCM-based strategy during AVS appears to have a significant beneficial effect on improving the success rate of bilateral cannulation, RAV cannulation and LAV cannulation.
Microbiome Metabolome Integration Platform (MMIP): a web-based platform for microbiome and metabolome data integration and feature identification
Authors: Gautam Anupam , Bhowmik Debaleena , Basu Sayantani , Zeng Wenhuan , Lahiri Abhishake , Huson Daniel H , Paul Sandip 
Published: September 2023

Abstract
A microbial community maintains its ecological dynamics via metabolite crosstalk. Hence, knowledge of the metabolome, alongside its populace, would help us understand the functionality of a community and also predict how it will change in atypical conditions. Methods that employ low-cost metagenomic sequencing data can predict the metabolic potential of a community, that is, its ability to produce or utilize specific metabolites. These, in turn, can potentially serve as markers of biochemical pathways that are associated with different communities. We developed MMIP (Microbiome Metabolome Integration Platform), a web-based analytical and predictive tool that can be used to compare the taxonomic content, diversity variation and the metabolic potential between two sets of microbial communities from targeted amplicon sequencing data. MMIP is capable of highlighting statistically significant taxonomic, enzymatic and metabolic attributes as well as learning-based features associated with one group in comparison with another. Furthermore, MMIP can predict linkages among species or groups of microbes in the community, specific enzyme profiles, compounds or metabolites associated with such a group of organisms. With MMIP, we aim to provide a user-friendly, online web server for performing key microbiome-associated analyses of targeted amplicon sequencing data, predicting metabolite signature, and using learning-based linkage analysis, without the need for initial metabolomic analysis, and thereby helping in hypothesis generation.
Horticulture could facilitate invasive plant range infilling and range expansion with climate change
Authors: Beaury Evelyn M , Allen Jenica M , Evans Annette E , Fertakos Matthew E , Pfadenhauer William G , Bradley Bethany A 
Published: September 2023

Abstract
Invasive plants are often sold as ornamental garden plants, but how often are species sold in the same locations as where they are invasive? To answer this question, we assessed the geography of ornamental plant sales in the United States in relation to existing invasions and potential invasion risk with climate change. Using a data set of 672 nurseries selling 89 invasive plants, we estimated the distance between nursery sales and invasive species’ observed distributions. We also used species range maps to identify nursery sales within current potential invaded ranges, as well as within species’ future potential ranges given climate change. Half of the species were sold by a nursery within 21 kilometers of an observed record of invasion. Under the current climate, horticulture could be seeding invasions for 73 of the 89 species studied, and horticulture could facilitate climate-driven range expansion of 25 of 89 species. Our results illustrate risks associated with horticultural introductions of invasive species, providing guidance for regulatory and educational interventions that reduce the spread of ongoing and future invasions.
Constraint breeds creativity: A brainstorming method to jumpstart out-of-the-box thinking for sustainability science
Authors: Gould Rachelle K , Saito Tomomi , Allen Karen E , Bonn Aletta , Chapman Mollie , Droz Laÿna , Herrmann Thora M , Himes Austin , Ishihara Hiroe , Coelho-Junior Marcondes G , Katsue Fukamachi , Kenter Jasper O , Muraca Barbara , Ortiz-Przychodzka Stefan , Pearson Jasmine , Tadaki Marc , Rono Betty J , Tamura Norie 
Published: September 2023

Abstract
Conservation science often addresses highly complex issues; creative approaches can help develop new ways of doing so. We describe constraint-based brainstorming, a 10-minute creativity-inducing exercise inspired by design thinking. Although we applied the method with the goal of developing creative environmental valuation methods, it is applicable to almost any complex, interdisciplinary environmental research problem. We tried the approach at two academic workshops, in Japan and in Germany. We generated, in each short activity, scores of unique ideas for the target question. We present this engaging activity as a way to simultaneously achieve multiple outcomes that can support innovative conservation science: quickly generate many seeds of ideas to address a challenge or goal, offer insight into nuances of and shared convictions related to the topic at hand, set a tone of creativity and breaking outside of established thought structures, and build community around a willingness to take risks and freely share ideas.
Quantifying the temporal stability of international fertilizer trade networks
Authors: Li Mu-Yao , Wang Li , Xie Wen-Jie , Zhou Wei-Xing 
Published: September 2023

Abstract
The importance of fertilizers to agricultural production is undeniable, and most economies rely on international trade for fertilizer use. The stability of fertilizer trade networks is fundamental to food security. However, quantifying the temporal stability of a fast-growing system, such as the international fertilizer trade, requires a multi-dimensional perception. Therefore, we propose a new method, namely the structural inheritance index, to distinguish the stability of the existing structure from the influence of the growing process. The well-known mutual information and Jaccard index are calculated for comparison. We use the three methods to measure the temporal stability of the overall network and different functional sub-networks of the three fertilizer nutrients N, P and K from 1990 to 2018. The international N, P and K trade systems all have a trend of increasing stability with the process of globalization. The existing structure in the fertilizer trading system has shown high stability since 1990, implying that the instability calculated by the Jaccard index in the early stage comes from the emergence of new trade. The stability of the K trade network is concentrated in large sub-networks, meaning that it is vulnerable to extreme events. The stable medium sub-network helps the N trade become the most stable nutrient trade. The P trade is clearly in the role of a catch-up player. Based on the analysis of the comparisons of three indicators, we concluded that all three nutrient trade networks enter a steady state.
Experiences of Extensive User Involvement through Vision Seminars in a Large IT Project
Authors: Cajander Åsa , Larusdottir Marta , Lind Thomas , Stadin Magdalena 
Published: September 2023

Abstract
As the complexity of IT systems increases, the demand for methods taking the whole work situation into account grows. The Vision Seminar (VS) process addresses the future usage of technologies in complex digital work environments. This paper describes the experiences of conducting the VS process in the context of a large IT project to improve study-administrative work. The participants and stakeholders' experiences of participating in VS workshops were studied as the effect the participants and stakeholders believed the vision might have. Data were gathered through interviews and a survey. The participants were confident that the time spent on workshops was worthwhile and that achieving the future described in the resulting vision was feasible. The stakeholders perceived the VS process as rigorous. They were happily surprised by the positive spirit and engagement displayed by the participants. The utility of the resulting vision not being obvious was the most notable weakness mentioned.
Supplemental feedings affect diet seasonality and niche width in urban Eurasian red squirrels
Authors: Takahata Yu , Uchida Kenta , Shimamoto Tatsuki , Kutsukake Nobuyuki , Shirai Kotaro , Tanaka Kentaro , Ito Motohiro 
Published: September 2023

Abstract
Urban environments are novel alternative habitats for wildlife. Anthropogenic food resources such as supplemental feeding (SF) are usually abundant, stable across seasons, and sometimes rich in calories. Although anthropogenic food resources could modify the seasonality and composition of the diets of urban animals, previous studies have been limited to qualitative assessments based on stomach content and food remains. Our study compared diet seasonality and niche width between rural and urban populations of Eurasian red squirrels (Sciurus vulgaris) in Hokkaido, Japan, using direct observation and stable isotope analysis. We found that dietary seasonality was lower in urban populations than in rural populations. The frequency of seed use was higher throughout the year in urban populations than in rural populations, possibly because of excessive seeds by SF in urban squirrels. Additionally, female body weights of the urban population were higher than those of the rural population. However, this was not true for males. Because high body weight can increase reproductive success in females, it is feasible that diet modification could contribute to population growth in urban squirrels. However, no differences in male body weight were observed, possibly due to energy loss caused by intense male–male competition at feeding sites. Our study highlights the importance of studying the multidimensional effects of anthropogenic foods on wildlife.
Redeeming education after progress: composing variations as a way out of innovation tyrannies
Authors: Thoilliez Bianca 
Published: September 2023

Abstract
At a time of pedagogical exhaustion, this article wants to imagine ways to redeem education, to spare education from its unaccomplished promises, reinvent and renew its vows, and make it somehow work towards possible futures. But how can this be done when there is no longer the old inherited faith in a direction of history with an end, no ‘telos’ nor faith that educational institutions will inevitably move societies forwards? Is there any ‘after’ if the arrow of history points in no direction? What can we collectively expect from education if we have no assurance that schooling can lead to anything better than what we are now, or that caring for truth will make people freer? In place of the modernist idea of progress, the alternative narrative that is being offered to school systems and teachers is what I will describe as the ‘innovation paradigm’. Within this framework what we are, what we have, and what is in place are presented as declining, inadequate, and unsatisfactory. This narrative has become so powerful that from a ‘pedagogical popular culture’ perspective it has turned into the mainstream way of thinking about our educational institutions, practices, and hopes. Would it not, however, be more pedagogically productive to speak of ‘variation’ instead of ‘innovation’? Might this be the potential path for redeeming education after progress? [Editorial note: this paper forms part of the suite of papers entitled ‘Education After Progress’.]
The plant siRNA landscape
Authors: Vaucheret Hervé , Voinnet Olivier 
Published: September 2023

Abstract
Whereas micro (mi)RNAs are considered the clean, noble side of the small RNA world, small interfering (si)RNAs are often seen as a noisy set of molecules whose barbarian acronyms reflect a large diversity of often elusive origins and functions. Twenty-five years after their discovery in plants, however, new classes of siRNAs are still being identified, sometimes in discrete tissues or at particular developmental stages, making the plant siRNA world substantially more complex and subtle than originally anticipated. Focusing primarily on the model Arabidopsis, we review here the plant siRNA landscape, including transposable elements (TE)-derived siRNAs, a vast array of non–TE-derived endogenous siRNAs, as well as exogenous siRNAs produced in response to invading nucleic acids such as viruses or transgenes. We primarily emphasize the extraordinary sophistication and diversity of their biogenesis and, secondarily, the variety of their known or presumed functions, including via non-cell autonomous activities, in the sporophyte, gametophyte, and shortly after fertilization.
Effect of a religious coping intervention of rational emotive behavior therapy on mental health of adult learners with type II diabetes
Authors: Okeke Nkechi Mercy , Onah Beatrice N. , Ekwealor Nwakaego Ebele , Ekwueme Stella Chinweudo , Ezugwu Joy Onyinyechukwu , Edeh Esther Nwarube , Okeke Polycarp M.D. , Ndille Roland , Onwuadi Charles C. , Amedu Amos N. , Nwaogaidu John Chidubem , Nnamani Rebecca Ginikanwa , Okolie Charles Nkem , Okoro Kingsley , Solomon Kingsley Christopher , Owonibi Ola Elizabeth 
Published: September 2023

Background:
Some previous studies have highlighted the high rate of mental health problems associated with type II diabetes (T2DM). The primary purpose of this study was to investigate the effect of a religious coping intervention of rational emotive behavior therapy (REBT) on the mental health of adult learners with T2DM.

Methods:
This study utilized a randomized controlled trial to select 146 adult learners with T2DM and mental health-related problems. The treatment group was made up of 73 adult learners, while the control group was also made up of 73 adult learners. The experimental group received 8 sessions of a religious coping intervention of REBT, while the control group received usual care. Data were collected using the patient health questionnaire, Warwick–Edinburgh mental well-being scale, and Kessler psychological distress scale. Repeated ANOVA and univariate analysis of covariance were used for data analyses.

Results:
The religious coping intervention of REBT substantially enhanced the mental health of adult learners with T2DM as measured by Warwick–Edinburgh mental well-being scale (P < .000) and patient health questionnaire (P < .000). The religious coping intervention of REBT significantly alleviated the psychological distress of adult learners with T2DM as measured by Kessler psychological distress scale (P < .000).

Conclusion:
In this study, it has been demonstrated that a religious coping intervention of REBT effectively improves the mental health of adult learners with T2DM. The study concludes that the religious coping intervention of REBT is a practical alternative medicine approach to enhancing the mental health of adult learners with T2DM.
Case report: Successful pregnancy complicated with non-cirrhotic portal hypertension in a lady who suffered from postpartum hemorrhage previously
Authors: Niu Xiaoxi , Gong Yanmin , Luo Xia 
Published: September 2023

Rationale:
Non-cirrhotic portal hypertension (NCPH) is characterized by the absence of cirrhotic modification of the liver and the patency of the portal and hepatic veins. When compared to the general population, NCPH is associated with an increased risk of maternal and perinatal morbidity and mortality during pregnancy. NCPH was present in the majority (74.1%) of pregnant women with portal hypertension. One (25%) out of every 4 pregnancies was complicated by variceal hemorrhage while pregnant. So far, there is still no consensus in the world about the treatment of this rare condition.

Patient concerns:
We have specifically illustrated a rare instance where the patient was diagnosed with NCPH and hypersplenism at the age of 8 and experienced a 3 L massive hemorrhage during labor induction as a result of her first pregnancy loss due to hypertension.

Diagnoses and Interventions:
The diagnosis of threatened preterm labor with cervical dilatation, gestational diabetes mellitus, massive splenomegaly with hypersplenism, portal vein hypertension, and parenchymal damage of kidney with impaired renal function led to the cesarean delivery of the second pregnancy at 29+3 weeks gestation without splenectomy after been evaluated by multispecialty team.

Outcomes:
She and her child were both in generally good condition 3 months after the operation.

Lessons:
Preconception counseling, ongoing follow-up, and monitoring are crucial in pregnant women with NCPH. A multidisciplinary team approach, with timely intervention and intensive monitoring, can help achieve optimal maternal–perinatal outcomes in pregnancies complicated with portal hypertension. Our case provided a successful treatment, but more guidelines for the management of NCPH are needed.
Bibliometric and visualized analysis of nonpharmaceutical TCM therapies for rheumatoid arthritis over the last 20 years using VOSviewer and CiteSpace software
Authors: Sun Xiaojun , Yin Hongqin , Zhu Yanhui , Li Ling , Shen Jun , Hu Kongfa 
Published: September 2023

Background:
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease that poses a significant threat to a patient’s quality of life. Commonly used drugs include glucocorticoids, nonsteroidal anti-inflammatory drugs, disease-modifying antirheumatic drugs, and biological agents; however, there are associated side effects. Complementary and alternative medicines can play positive roles. Bibliometric analysis of herbal medicines for RA has been conducted, but current research trends in nonpharmaceutical traditional Chinese medicine (TCM) therapies for the treatment of RA have not been studied. Here, we conducted a bibliometric analysis of the application of nonpharmaceutical TCM therapies for RA over the last 20 years.

Methods:
We retrieved relevant literature from the Web of Science Core Collection database and used VOSviewer and CiteSpace software for analysis. Visualized maps were then generated to display the relationships between the author, country, institution, and keywords.

Results:
A total of 567 articles were included in the final analysis. The number of annual publications on nonpharmaceutical TCM interventions for RA increased over the study period. The journal with the highest number of publications on this topic was Evidence-based Complementary and Alternative Medicine; however, Cochrane Database of Systematic Reviews had the most citations. Collaborations were observed among worldwide institutions, with the People’s Republic of China playing a dominant role in the research on treatment of RA using nonpharmaceutical TCM therapies. Ernst E was the most productive author, with 11 articles, whereas Green S had the highest number of citations (287) at the time of retrieval. Specific improvements in the efficacy and selection of nonpharmaceutical therapies were the main research hotspots based on citation burst analysis.

Conclusion:
This study characterizes the trends in the literature for nonpharmaceutical TCM therapy for RA over the past 20 years; showcasing the current research status for relevant researchers and their teams and providing a reference for future research directions.
Study of monomelic amyotrophy of the lower limbs in the territory of the Western Balkans: Case series
Authors: Djordjevic Gordana , Milosevic Vuk , Stojanov Aleksandar 
Published: September 2023

Rationale:
Monomelic amyotrophy is a rare form of motor neuron disease in which the neurogenic atrophy is restricted to 1 limb, mostly the distal part of the arm. The disease most often occurs in Asia, especially in Japan and India, while in European countries, this disease is rarely recognized. Registration and publication of new cases of this disease aims to increase the awareness of clinicians about the existence of this disease in European countries, and with the aim of easier recognition and faster diagnosis of this essentially benign disorder.

Patient concerns:
Five patients with signs of atrophy of the muscles of 1 leg were examined at our Institution.

Diagnoses:
The criteria for selecting patients were as follows: clinical evidence of wasting and weakness confined to the 1 lower limb; progressive course, or initial progression followed by stationary course; absence of any definite sensory loss or central nervous system involved; no evidence of compression lesion of the spinal cord.

Interventions:
The clinical characteristics of our patients were similar to those previously described in the literature. The characteristic clinical features were sporadic occurrence, predominance in males with an initially progressive course for 2 to 5 years followed by a stationary state. There was no family history of neuromuscular disease.

Outcomes:
The electromyographic finding was consistent with a chronic neuropathic disorder. Magnetic resonance imaging of the lumbosacral spine excluded intraspinal pathologies and root compression in all cases.

Lessons subsection:
Monomelic amyotrophy of the lower limb is a rare disease that should be considered in cases of slow progressive unilateral amyotrophy of a single leg, especially in younger and middle-aged men, not only in Asia but also in the Western Balkans and Europe.