bluuebunny/crossref_metadata_2025_split huggingface dataset:
The accuracy of implant placement using a combination of static and dynamic computer‐assisted implant surgery in fully edentulous arches: A prospective controlled clinical study
Authors: Lorwicheanrung Jarungvit , Mahardawi Basel , Arunjaroensuk Sirida , Kaboosaya Boosana , Mattheos Nikos , Pimkhaokham Atiphan 
Published: September 2023

AbstractObjectiveTo compare the accuracy of implant position, using a combination of static and dynamic computer‐assisted implant surgery (CAIS), with either static, dynamic, or freehand implant placement, in fully edentulous arches.Materials and MethodsTwenty‐one patients with a total of 88 fixtures were included. Implants were divided equally into four groups: a combination of static and dynamic CAIS (SD group), static CAIS (S group), dynamic CAIS (D group), and freehand placement (FH group). Angular deviation, as well as the 3D platform and apex deviations, were measured for all groups. Furthermore, the direction of implant deviation was recorded and compared.ResultsThe FH group showed significantly more deviation compared to all groups, considering all the aspects, and at both the implant platform and apex. A significant difference in angular deviation between the SD and S groups (p < .001), and between the SD and D groups (p < .001) was noted, favoring the SD group. When evaluating implant distribution, the FH group showed a tendency towards the buccal, apical, and distal directions at platform and apex, while in the D group, implants shifted more to the buccal. In contrast, the SD group did not show a trend toward any specific direction. The S and SD groups did not show a statistical significance considering any direction.ConclusionsThe combination of static and dynamic CAIS increases the accuracy of implant placement in fully edentulous arches when compared with either static or dynamic CAIS alone, as well as freehand placement.
Allergic contact dermatitis to footwear in Thailand: Prevalence, clinical characteristics and common allergens
Authors: Chaiyabutr Chayada , Sereeaphinan Chudapa , Prasertsook Suthasanee , Boonchai Waranya 
Published: September 2023

AbstractBackgroundFootwear contact allergy is caused by exposure to allergens in shoes. The prevalence and common allergens vary by region and time due to differences in customs and lifestyle.ObjectivesTo determine the clinical characteristics and common allergens of patients with footwear‐related allergic contact dermatitis (ACD) who attended Siriraj Hospital in Bangkok, Thailand, between 2001 and 2020.MethodsThe medical records of 247 patients with clinically suspected footwear dermatitis who underwent patch testing were reviewed.ResultsThe prevalence of ACD to footwear was 1.8%. Females were predominant (71.6%). The three most common allergens were carba mix (7.7%), mercapto mix (6.9%) and potassium dichromate (6.9%). According to the allergens found, rubber (14.2%), adhesives (7.7%) and leathers (6.9%) were the three most common groups. Dorsal‐limited skin lesions were significantly associated with footwear ACD.ConclusionRubber and leather allergens were still the most common culprit allergens. Dermatologists should keep up‐to‐date on common allergens in footwear and emerging allergens to include in patch test series.
Estimating the cost‐effectiveness of intermittently scanned continuous glucose monitoring in adults with type 1 diabetes in England
Authors: Elliott Rachel A. , Rogers Gabriel , Evans Mark L. , Neupane Sankalpa , Rayman Gerry , Lumley Sarah , Cranston Iain , Narendran Parth , Sutton Christopher J. , Taxiarchi Vicky P. , Burns Matthew , Thabit Hood , Wilmot Emma G. , Leelarathna Lalantha ,   FLASH–UK Trial Study Group
Published: September 2023

AbstractObjectiveWe previously showed that intermittently scanned continuous glucose monitoring (isCGM) reduces HbA1c at 24 weeks compared with self‐monitoring of blood glucose with finger pricking (SMBG) in adults with type 1 diabetes and high HbA1c levels (58–97 mmol/mol [7.5%–11%]). We aim to assess the economic impact of isCGM compared with SMBG.MethodsParticipant‐level baseline and follow‐up health status (EQ‐5D‐5L) and within‐trial healthcare resource‐use data were collected. Quality‐adjusted life‐years (QALYs) were derived at 24 weeks, adjusting for baseline EQ‐5D‐5L. Participant‐level costs were generated. Using the IQVIA CORE Diabetes Model, economic analysis was performed from the National Health Service perspective over a lifetime horizon, discounted at 3.5%.ResultsWithin‐trial EQ‐5D‐5L showed non‐significant adjusted incremental QALY gain of 0.006 (95% CI: −0.007 to 0.019) for isCGM compared with SMBG and an adjusted cost increase of £548 (95% CI: 381–714) per participant. The lifetime projected incremental cost (95% CI) of isCGM was £1954 (−5108 to 8904) with an incremental QALY (95% CI) gain of 0.436 (0.195–0.652) resulting in an incremental cost‐per‐QALY of £4477. In all subgroups, isCGM had an incremental cost‐per‐QALY better than £20,000 compared with SMBG; for people with baseline HbA1c >75 mmol/mol (9.0%), it was cost‐saving. Sensitivity analysis suggested that isCGM remains cost‐effective if its effectiveness lasts for at least 7 years.ConclusionWhile isCGM is associated with increased short‐term costs, compared with SMBG, its benefits in lowering HbA1c will lead to sufficient long‐term health‐gains and cost‐savings to justify costs, so long as the effect lasts into the medium term.
Links between personality, reproductive success and re‐pairing patterns in a long‐lived seabird
Authors: McCully Fionnuala R. , Descamps Sébastien , Harris Stephanie M. , Mckendrick Freddie , Gillies Natasha , Cornell Stephen J. , Hatchwell Ben J. , Patrick Samantha C. 
Published: September 2023

AbstractIn long‐lived monogamous species, the trigger of costly re‐pairing is not always clear. Limited research suggests that within‐pair behavioural compatibility may be an important driver of partnership success, as cooperation should be enhanced when pair members' decisions complement one another. Animals' decision‐making processes are influenced by personality traits – defined as individual differences in behaviour that are stable in time. Despite the potential for the personality trait ‘boldness’ to (a) directly impact individual willingness to re‐pair and (b) indirectly impact re‐pairing choices via reproductive success, there is currently little work exploring how re‐pairing decisions might be impacted by the pair members' personalities. Using a 13‐year dataset, we investigated whether within‐pair boldness and its relationship with breeding success explained re‐pairing patterns of black‐legged kittiwakes (Rissa tridactyla), breeding in two Arctic colonies. We found that pairs with dissimilar boldness levels were more likely to experience breeding failure and that failed pairs were more likely to re‐pair the following year. Despite this, only one colony displayed evidence of assortative mating by boldness, and there was no indication that re‐pairing impacted reproductive success the following season. Neither individual nor pair boldness directly influenced re‐pairing probability; however, in both colonies, re‐pairing birds chose partners that were slightly more similar to themselves in boldness than their previous mates. These results imply an indirect pathway by which poorer behavioural compatibility within pairs may lead to breeding failure and ultimately re‐pairing. Our findings highlight the importance of behavioural compatibility, and possibly personality, in mitigating sexual conflict and its population‐specific drivers.
Engaged ETFs and firm performance
Authors: El Kalak Izidin , Hudson Robert , Tosun Onur K. 
Published: September 2023

AbstractExchange Traded Funds (ETFs) have often tracked indices and charged low fees so their incentives to improve firm performance are questionable although little empirical work has investigated this issue. Theoretically, however, we expect firms to perform better when held by more engaged ETFs. We develop a new measure of engagement using a weighted‐average concentration measure which captures the combined effect of the concentration of the portfolios of the ETFs investing in a firm and the ownership of the firm by those ETFs. Using ETFs' investment in US‐listed firms for the period 2000–2019, we confirm our expectations that more engaged ETFs improve firm performance.
Diverse pathways for climate resilience in marine fishery systems
Authors: Eurich Jacob G. , Friedman Whitney R. , Kleisner Kristin M. , Zhao Lily Z. , Free Christopher M. , Fletcher Meghan , Mason Julia G. , Tokunaga Kanae , Aguion Alba , Dell'Apa Andrea , Dickey‐Collas Mark , Fujita Rod , Golden Christopher D. , Hollowed Anne B. , Ishimura Gakushi , Karr Kendra A. , Kasperski Stephen , Kisara Yuga , Lau Jacqueline D. , Mangubhai Sangeeta , Osman Layla , Pecl Gretta T. , Schmidt Jörn O. , Allison Edward H. , Sullivan Patrick J. , Cinner Joshua E. , Griffis Roger B. , McClanahan Timothy R. , Stedman Richard C. , Mills Katherine E. 
Published: September 2023

AbstractBoth the ecological and social dimensions of fisheries are being affected by climate change. As a result, policymakers, managers, scientists and fishing communities are seeking guidance on how to holistically build resilience to climate change. Numerous studies have highlighted key attributes of resilience in fisheries, yet concrete examples that explicitly link these attributes to social‐ecological outcomes are lacking. To better understand climate resilience, we assembled 18 case studies spanning ecological, socio‐economic, governance and geographic contexts. Using a novel framework for evaluating 38 resilience attributes, the case studies were systematically assessed to understand how attributes enable or inhibit resilience to a given climate stressor. We found population abundance, learning capacity, and responsive governance were the most important attributes for conferring resilience, with ecosystem connectivity, place attachment, and accountable governance scoring the strongest across the climate‐resilient fisheries. We used these responses to develop an attribute typology that describes robust sources of resilience, actionable priority attributes and attributes that are case specific or require research. We identified five fishery archetypes to guide stakeholders as they set long‐term goals and prioritize actions to improve resilience. Lastly, we found evidence for two pathways to resilience: (1) building ecological assets and strengthening communities, which we observed in rural and small‐scale fisheries, and (2) building economic assets and improving effective governance, which was demonstrated in urban and wealthy fisheries. Our synthesis presents a novel framework that can be directly applied to identify approaches, pathways and actionable levers for improving climate resilience in fishery systems.
Prediction model of rail head check initiation considering wear and nonlinear fatigue damage accumulation
Authors: Li Junpeng , Weng Zhiyi , Zhou Yu , Cheng Zhongning , Wang Chi , Lu Zhechao , Wang Zheng 
Published: September 2023

AbstractWear and rolling contact fatigue (RCF) cracks are the key defects affecting the service life of heavy‐haul railways in China. In this study, based on the influences of the loading sequence and the interaction between adjacent loads, a modified nonlinear fatigue damage accumulation model under the steady‐state wheel–rail contact was developed to predict the coexistence of wear growth and head check (HC) initiation. A twin‐roller fatigue test was designed and performed, and the testing data were compared with the predicted data to verify the established model. Compared with the linear model, the nonlinear model yielded the faster fatigue damage with an HC initiation life of 2.58 × 105 wheel cycles, which was 24.34% less than that of the linear model. In addition, the HC initiation lives obtained from the nonlinear and linear models were close to the median and upper limits observed in the field, respectively. The results of the linear and nonlinear models were respectively 41.3% and 22.5% higher than the two‐round test results. The result of the nonlinear model was closer to the two‐round test result of 2 × 105.
Filter‐feeding gelatinous macrozooplankton response to climate change and implications for benthic food supply and global carbon cycle
Authors: Clerc Corentin , Aumont Olivier , Bopp Laurent 
Published: September 2023

AbstractIt is often suggested that gelatinous zooplankton may benefit from anthropogenic pressures of all kinds and in particular from climate change. Large pelagic tunicates, for example, are likely to be favored over other types of macrozooplankton due to their filter‐feeding mode, which gives them access to small preys thought to be less affected by climate change than larger preys. In this study, we provide model‐based estimate of potential community changes in macrozooplankton composition and estimate for the first time their effects on benthic food supply and on the ocean carbon cycle under two 21st‐century climate‐change scenarios. Forced with output from an Earth System Model climate projections, our ocean biogeochemical model simulates a large reduction in macrozooplankton biomass in response to anthropogenic climate change, but shows that gelatinous macrozooplankton are less affected than nongelatinous macrozooplankton, with global biomass declines estimated at −2.8% and −3.5%, respectively, for every 1°C of warming. The inclusion of gelatinous macrozooplankon in our ocean biogeochemical model has a limited effect on anthropogenic carbon uptake in the 21st century, but impacts the projected decline in particulate organic matter fluxes in the deep ocean. In subtropical oligotrophic gyres, where gelatinous zooplankton dominate macrozooplankton, the decline in the amount of organic matter reaching the seafloor is reduced by a factor of 2 when gelatinous macrozooplankton are considered (−17.5% vs. −29.7% when gelatinous macrozooplankton are not considered, all for 2100 under RCP8.5). The shift to gelatinous macrozooplankton in the future ocean therefore buffers the decline in deep carbon fluxes and should be taken into account when assessing potential changes in deep carbon storage and the risks that deep ecosystems may face when confronted with a decline in their food source.
Factors associated with maintaining walking ability postoperation for hip fractures and the predictive value of the CGA7 score for postoperative walking ability
Authors: Morisaki Shinsuke , Yoshii Kengo , Tsuchida Shinji , Oda Ryo , Okubo Naoki , Takahashi Kenji 
Published: September 2023

AimPatients with hip fractures have a high rate of mortality or decreased mobility, despite early operative treatment and rehabilitation. The first aim of this study was to investigate the factors of decreased walking ability after hip fracture based on whether walking ability was or was not maintained postoperatively. The second aim was to examine the usefulness of the Comprehensive Geriatric Assessment 7 (CGA7), modified from the conventional Comprehensive Geriatric Assessment, for predicting postoperative walking ability.MethodsThis study included patients who were treated surgically for hip fractures. We divided patients by whether they did or did not maintain their walking ability postoperatively. We registered the following demographic data: walking ability preadmission and at discharge, CGA7 score, cognitive impairment, the patient's prefracture status, fracture type, surgical waiting time, hospital stay duration, limitation of weight‐bearing, postoperative complications, transfer to rehabilitation hospital, final living place, and follow‐up period. The characteristics of the two groups were compared using Wilcoxon's rank‐sum test, the chi‐squared test, or Fisher's exact test.ResultsAmong 855 patients, 616 (73.0%) patients maintained walking ability and 239 (27.0%) patients did not. Multivariate logistic regression revealed that the factors of age, sex, preoperative walking ability, and postoperative complications were significantly associated with maintaining postoperative walking ability. Furthermore, the higher the CGA7 score, the more likely were patients to maintain their walking ability (odds ratio, 0.72; 95% confidence interval, 0.61–0.85; P < 0.001).ConclusionsPatients who had a low CGA7 score had the potential risk of decreased walking ability. Geriatr Gerontol Int 2023; 23: 830–835.
Can lowering the minimum age of criminal responsibility be justified? A critical review of China's recent amendment
Authors: Wong Aaron H. L. 
Published: September 2023

AbstractIn 2021, China amended its law on the minimum age of criminal responsibility (MACR), lowering the MACR of two specified offences to twelve years. As a result, China now has three different levels of MACR for different offences. Based on the position in China, this article argues that while lowering the MACR against the international trend can be justified as a necessary measure to tackle serious crimes committed by children, creating different levels of MACR based on the types of crime is wrong in principle. This article further considers the classic dilemma in setting an absolute MACR, which results in either freeing the guilty or convicting the innocent. It is argued that setting a relatively low MACR accompanied by robust safeguards of doli incapax, child immaturity defence, diversion and wider sentencing options would allow a better assessment of children's culpability and better serve the interests of justice. It is also suggested that lowering the MACR will not unjustifiably undermine children's rights if the juvenile justice system could ensure only those truly culpable could be convicted and that the option of prosecution is reserved as a last resort.
Effects of the web‐based birth preparation programme and motivational interviews on primigravida women: Randomized‐controlled study
Authors: Yesildag Birnur , Golbasi Zehra 
Published: September 2023

AbstractAimThis study aimed to identify the effects of a web‐based birth preparation programme based on the Health Belief Model and supported by motivational interviews on fear of childbirth, self‐efficacy and the labour process in primigravida women.MethodsThe study was conducted in a single‐blind, randomized controlled design with 73 pregnant women. The Birth Health Belief Scale, the Wijma Delivery Expectation/Experience Questionnaire A‐B, the Childbirth Self‐efficacy Scale and the Labour Process Assessment forms were used to collect data. Five sessions of motivational interviews were held with the pregnant women in the experimental group, while those in the control group were administered placebo education.ResultsFear of birth was lower, and the birth self‐efficacy total score was higher in the experimental group. None of the groups indicated significant differences in terms of their mode of delivery.ConclusionHealth Belief Model‐based web‐based birth preparation programme and motivational interviews were found to reduce the fear of birth, increase self‐efficacy and positively affect the birth process in primigravida women.
Capital Structure Instability
Authors: DeAngelo Harry , Roll Richard 
Published: September 2023

This article summarizes the evidence from the authors’ recent study published in the Journal of Finance that documented the extent of the variation in the capital structures of individual public companies over long time horizons. It also reports the results of an exploratory investigation into the sources of variation over time in leverage ratios—an investigation that included case analyses of leverage instability at 24 U.S. companies that were included in the Dow Jones Industrial Average at some point in their histories.The main finding of the authors’ study is that substantial instability in leverage has been the norm at publicly held nonfinancial companies. “Episodic” cases of leverage stability were observed from time to time, but they were the exception, not the rule. Such cases almost always involved companies with low leverage ratios, and they invariably proved to be short‐lived, rarely exceeding a decade or two. Leverage was found to be “sticky” during periods lasting just a few years, but a company's currently high (or low) leverage became an increasingly poor predictor of whether its future leverage would be high (or low) as the amount of time between leverage observations lengthened.When attempting to explain companyspecific changes in leverage after extended periods of stability, the authors found a strong connection with company expansion and investment. At the same time, they found no systematic relations between company‐specific leverage changes and changes in industry leverage, company profitability, or other determinants of leverage that have been emphasized in previous academic studies. The authors' case analyses reinforced their finding that capital structure changes were often linked to the funding of company expansions, but such changes were also sometimes designed to support established payout policies while preserving financing flexibility.
ROR2 deficit may induce the tetralogy of Fallot via down‐regulating of β‐catenin/SOX3/HSPA6 in vitro and in vivo
Authors: Guo Rui , Guo Yiran Zhou , Zhou Qing , Li Guoju , Du Zhanghui , Shi Yefei , Xing Quansheng 
Published: September 2023

AbstractTetralogy of Fallot (TOF) is the highly conventional appearance of cyanotic congenital heart disease. Our study aimed to assess the involvement of receptor tyrosine kinase‐like orphan receptor 2 (ROR2) in TOF and elucidate the specific mechanism. Upon investigation of human tissue samples, we observed a decrease in ROR2 expression in TOF patients compared to healthy control individuals. Transcriptome analysis revealed diminished ROR2 expression in TOF pathological samples relative to normal tissues. Of the 2246 genes that exhibited altered expression, 886 were upregulated, while 1360 were down‐regulated. KEGG analysis and GO analysis of the differentially expressed genes indicated that these genes were significantly enriched in the Wnt signalling pathway, apoptosis and cardiac development function. Importantly, ROR2 was the only gene shared among the three pathways. Furthermore, interference with ROR2 promotes apoptosis and curtails cell proliferation in vitro. The knockdown of the ROR2 gene in AC16 cells resulted in a significant decrease in Edu‐positive cells. Flow cytometry studies indicated an increase in the percentage of cells in the S phase. In contrast, the G2/M cell cycle transition was blocked in the ROR2‐knockdown group, leading to a significant increase in apoptosis. Moreover, the CCK‐8 cell viability assay demonstrated a reduced proliferation in the ROR2‐knockdown group. Furthermore, both in vivo and in vitro data indicated that the expression of HSPA6 (Recombinant Heat Shock 70 kDa Protein6), an essential gene enriched in cardiac tissue and associated with apoptosis, was down‐regulated following ROR2 knockdown mediated by the β‐catenin/SOX3 signalling pathway. In conclusion, low expression of ROR2 plays a crucial role in the occurrence and development of TOF, which may be related to the downregulation of HSPA6 through the β‐catenin/SOX3 signalling pathway.