bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fourier‐transform infrared study on effects of ageing, oestrogen level and altered dietary loading on rat mandibular condylar cartilage
Authors: Hauru Riikka , Rieppo Lassi , Tuomisto Teresa , Yu Jia , Laaksonen Sakari , Saarakkala Simo , Raustia Aune , Pirttiniemi Pertti 
Published: August 2023

AbstractObjectiveMandibular condylar cartilage (MCC) of the rat was examined with the Fourier‐transform infrared (FITR) spectroscopic imaging to study the effects of ageing, oestrogen level and altered dietary loading on the structure of MCC.Materials and MethodsThe Sprague–Dawley rats (n = 96) aged 5 and 14 months were divided into 12 subgroups according to age, oestrogen status (ovariectomized [OVX], non‐ovariectomized [non‐OVX)]) and diet (hard, normal, soft). Specimens of the MCC were examined with FTIR spectroscopic imaging to quantify the distribution of collagens and proteoglycans. MCC was divided sagittally into three segments: anterior, most superior and posterior. From each segment, the collagen and proteoglycan contents at different depths of cartilage were statistically compared between the groups using an N‐way analysis of variance (ANOVA).ResultsThe amount of collagen content was significantly associated with old age in the deep layer of the anterior segment and in the middle layer of the posterior segment of MCC. In the deep layer of the most superior segment, the collagen content also increased with ageing. The amount of proteoglycan content increased significantly when dietary loading increased, and the oestrogen level decreased in the deep layer of the most superior segment of MCC.ConclusionAgeing, oestrogen level and altered dietary loading have a significant effect on the location and content of collagens and proteoglycans of rat MCC. Ageing significantly increased the amount of collagen content in the superior and posterior segments, being highest in the older soft‐diet rats. Decreased oestrogen levels and increased dietary loading increased the amount of proteoglycan content.
Communities of practice in residential aged care: A rapid review
Authors: Read Martin , Peters Sanne , Bennett Noleen , Francis Jill J. , Fetherstonhaugh Deirdre , Lim Wen Kwang , Tropea Joanne 
Published: August 2023

AbstractBackgroundCommunities of practice (CoPs) have the potential to help address the residential aged care system's need for continuing education and quality improvement. CoPs have been used in healthcare to improve clinical practice; however, little is known about their application to the unique residential aged care context.ObjectivesThis rapid review of CoPs for residential aged care was conducted to summarise the features of CoPs, how they are developed and maintained, and assess their effectiveness.MethodsMEDLINE and CINAHL databases were searched for studies published from January 1991 to November 2022 about CoPs in residential aged care. Data were extracted regarding the CoPs' three key features of ‘domain’, ‘community’ and ‘practice’ as described by Wenger and colleagues. Kirkpatrick's four levels of evaluation (members' reactions, learning, behaviour and results) was used to examine studies on the effectiveness of CoPs. The Mixed Methods Appraisal Tool was used for quality appraisal.ResultsNineteen articles reported on 13 residential aged care CoPs. Most CoPs aimed to improve care quality (n = 9, 69%) while others aimed to educate members (n = 3, 23%). Membership was often multidisciplinary (n = 8, 62%), and interactions were in‐person (n = 6, 46%), online (n = 3, 23%) or both (n = 4, 31%). Some CoPs were developed with the aid of a planning group (n = 4, 31%) or as part of a larger collaborative (n = 4, 31%), and were maintained using a facilitator (n = 7, 54%) or adapted to member feedback (n = 2, 15%). Thirteen (81%) studies evaluated members' reactions, and three (24%) studies assessed members' behaviour. The heterogeneity of studies and levels of reporting made it difficult to synthesise findings.ConclusionsThis review revealed the variation in why, and how, CoPs have been used in residential aged care, which is consistent with previous reviews of CoPs in healthcare. While these findings can inform the development of CoPs in this context, further research is needed to understand how CoPs, including the membership makeup, delivery mode, facilitator type and frequency of meetings, impact quality of care.
Roles of the pepper JAZ protein CaJAZ1‐03 and its interacting partner RING‐type E3 ligase CaASRF1 in regulating ABA signaling and drought responses
Authors: Koh Haeji , Joo Hyunhee , Lim Chae Woo , Lee Sung Chul 
Published: August 2023

AbstractPlants have developed various defense mechanisms against environmental stresses by regulating hormone signaling. Jasmonic acid (JA) is a major phytohormone associated with plant defense responses. JASMONATE ZIM‐DOMAIN (JAZ) proteins play a regulatory role in repressing JA signaling, impacting plant responses to both biotic and abiotic stresses. Here, we isolated 7 JAZ genes in pepper and selected CA03g31030, a Capsicum annuum JAZ1‐03 (CaJAZ1‐03) gene, for further study based on its expression level in response to abiotic stresses. Through virus‐induced gene silencing (VIGS) in pepper and overexpression in transgenic Arabidopsis plants, we established the functional role of CaJAZ1‐03. Functional studies revealed that CaJAZ1‐03 dampens abscisic acid (ABA) signaling and drought stress responses. The cell‐free degradation assay showed faster degradation of CaJAZ1‐03 in drought‐ or ABA‐treated pepper leaves compared to healthy leaves. Conversely, CaJAZ1‐03 was completely preserved under MG132 treatment, indicating that CaJAZ1‐03 stability is modulated via the ubiquitin‐26s proteasome pathway. We also found that the pepper RING‐type E3 ligase CaASRF1 interacts with and ubiquitinates CaJAZ1‐03. Additional cell‐free degradation assays revealed a negative correlation between CaJAZ1‐03 and CaASRF1 expression levels. Collectively, these findings suggest that CaJAZ1‐03 negatively regulates ABA signaling and drought responses and that its protein stability is modulated by CaASRF1.
Agricultural tillage practice and rhizosphere selection interactively drive the improvement of soybean plant biomass
Authors: Chen Shi , Wang Yang , Gao Jiamin , Chen Xingyu , Qi Jiejun , Peng Ziheng , Chen Beibei , Pan Haibo , Liang Chunling , Liu Jiai , Wang Yihe , Wei Gehong , Jiao Shuo 
Published: August 2023

AbstractRhizosphere microbes play key roles in plant growth and productivity in agricultural systems. One of the critical issues is revealing the interaction of agricultural management (M) and rhizosphere selection effects (R) on soil microbial communities, root exudates and plant productivity. Through a field management experiment, we found that bacteria were more sensitive to the M × R interaction effect than fungi, and the positive effect of rhizosphere bacterial diversity on plant biomass existed in the bacterial three two‐tillage system. In addition, inoculation experiments demonstrated that the nitrogen cycle‐related isolate Stenotrophomonas could promote plant growth and alter the activities of extracellular enzymes N‐acetyl‐
d‐glucosaminidase and leucine aminopeptidase in rhizosphere soil. Microbe‐metabolites network analysis revealed that hubnodes Burkholderia‐Caballeronia‐Paraburkholderia and Pseudomonas were recruited by specific root metabolites under the M × R interaction effect, and the inoculation of 10 rhizosphere‐matched isolates further proved that these microbes could promote the growth of soybean seedlings. Kyoto Encyclopaedia of Genes and Genomes pathway analysis indicated that the growth‐promoting mechanisms of these beneficial genera were closely related to metabolic pathways such as amino acid metabolism, melatonin biosynthesis, aerobactin biosynthesis and so on. This study provides field observation and experimental evidence to reveal the close relationship between beneficial rhizosphere microbes and plant productivity under the M × R interaction effect.
Association between the COVID‐19 pandemic and psychiatric symptoms in people with preexisting obsessive‐compulsive, eating, anxiety, and mood disorders: a systematic review and meta‐analysis of before‐after studies
Authors: van Reekum Emma A , Woo Julia J , Petropoulos Jo‐Anne , Samaan Zainab , Mbuagbaw Lawrence 
Published: August 2023

AimTo determine whether the coronavirus disease 2019 (COVID‐19) pandemic was associated with a change in psychiatric symptoms in people with preexisting obsessive‐compulsive, eating, anxiety, and mood disorders compared to their prepandemic levels.MethodsWe searched MEDLINE, CINAHL, PsycINFO, and Embase from inception until February 16, 2022. Studies were included if they reported prepandemic and during‐pandemic psychiatric symptoms, using validated scales, in people with preexisting mood, anxiety, eating, or obsessive‐compulsive disorders. Two reviewers independently screened studies, extracted data, and assessed evidence certainty. Random‐effects meta‐analyses were conducted. Effect sizes were reported as standardized mean differences (SMDs) with 95% confidence intervals (CIs).ResultsEighteen studies from 10 countries were included. Of the 4465 included participants, 68% were female and the average age was 43 years. Mood and obsessive‐compulsive disorders were the most studied disorders. During‐pandemic psychiatric measurements were usually collected during nationwide lockdown. Obsessive‐compulsive symptoms worsened among people with obsessive‐compulsive and related disorders, with a moderate effect size (N = 474 [six studies], SMD = −0.45 [95% CI, −0.82 to −0.08], I2 = 83%; very low certainty). We found a small association between the COVID‐19 pandemic and reduced anxiety symptoms in people with mood, anxiety, obsessive‐compulsive, and eating disorders (N = 3738 [six studies], SMD = 0.11 [95% CI, 0.02–0.19], I2 = 63%; very low certainty). No change in loneliness, depressive, or problematic eating symptoms was found.ConclusionPeople with obsessive‐compulsive and related disorders may benefit from additional monitoring during the COVID‐19 pandemic and possibly future pandemics. Other psychiatric symptoms were stable in people with the specific disorders studied. Overall, evidence certainty was very low.
Needle‐based confocal laser endomicroscopy for real‐time granuloma detection
Authors: Kramer Tess , Wijmans Lizzy , van Heumen Saskia , Bansal Sandeep , Jeannerat Dawn , Manley Christopher , de Bruin Martijn , Bonta Peter I. , Annema Jouke T. 
Published: August 2023

AbstractBackground and ObjectiveNeedle‐based confocal laser endomicroscopy (nCLE) allows real‐time microscopic imaging at the needle tip. nCLE malignancy criteria are used for tool‐in‐lesion confirmation during bronchoscopic lung nodule analysis. However, to date, nCLE criteria for granulomas are lacking. The aim was to identify and validate nCLE granuloma criteria and assess if blinded raters can distinguish malignant from granulomatous nCLE videos.MethodsIn patients with suspected sarcoidosis, nCLE‐imaging of mediastinal lymph nodes was performed during endoscopic ultrasound procedures, followed by needle aspiration. nCLE granuloma criteria were identified by comparison with pathology and final diagnoses. Additionally, nCLE‐videos of granulomatous lung nodules part of prospective trials and clinical care were compared to the proposed nCLE granuloma criteria. Blinded raters validated nCLE videos of sarcoid and reactive mediastinal lymph nodes and malignant and granulomatous lung nodules twice.ResultsGranuloma criteria were identified (brighter‐toned, homogeneous and well‐demarcated lesions) based on nCLE‐imaging in 14 sarcoidosis patients. Raters evaluated 26 nCLE‐videos obtained in lymph nodes (n = 15 sarcoidosis; n = 11 reactive and total of 260 ratings). Granuloma criteria were recognized with 88% accuracy. The inter‐observer (κ = 0.63, 95% CI 0.54–0.72) and intra‐observer reliability (κ = 0.70 ± 0.06) were substantial. Based on 12 nCLE‐videos obtained in lung nodules (n = 4 granulomas, n = 6 malignancy, n = 2 malignancy + granulomas and total of 120 ratings) granuloma and malignancy criteria were recognized with 92% and 75% accuracy.ConclusionnCLE imaging facilitates real‐time granuloma visualization. Blinded raters accurately and consistently recognized granulomas on nCLE‐imaging and distinguished nCLE granuloma criteria from malignancy. Our data show the potential of nCLE as a real‐time bronchoscopic guidance tool for lung nodule analysis.
Preventative plasmapheresis in a diabetic pregnant patient with hypertriglyceridemia and distal pancreatectomy
Authors: Hogan Keenan O. 
Published: August 2023

AbstractBackgroundPregnant patients with a history of hypertriglyceridemia are at increased risk for development of acute pancreatitis. When conservative management fails to maintain triglyceride levels less than 250–500 mg dL−1, implementation of pregnancy category C medications to prevent pancreatitis must be considered. Plasmapheresis rapidly reduces triglyceride levels and has been reported as a successful third‐line therapy for hypertriglyceridemia‐induced acute pancreatitis in a limited number of pregnant patients. Use of preventative plasmapheresis as a bridge to delivery is not well characterised.Case PresentationWe report an outpatient plasmapheresis regimen for the control of hypertriglyceridemia in a pregnant patient with a history of diabetes mellitus, hypertriglyceridemia, distal pancreatectomy, and repeat pregnancy loss. During the second trimester, refractory triglyceride levels increased up to 3438 mg dL−1 by 28 weeks gestation. Given the patient's high risk for recurrent pancreatitis and limited remaining pancreatic parenchyma, she was treated acutely with two single‐plasma‐volume exchanges with 100% albumin over 2 days, decreasing the triglyceride level to 559 mg dL−1. Subsequent plasmapheresis every 7 to 9 days maintained a triglyceride level of 320–1296 mg dL−1. The patient experienced no adverse effects and remained outpatient until successful scheduled delivery for hypertension at 33 weeks gestation.DiscussionFor select patients, early escalation to plasmapheresis may prevent morbidity and mortality associated with acute pancreatitis. An individualised plasmapheresis regimen can serve as a bridge to delivery, which requires close observation and the coordination of a multidisciplinary team.
Dynamical cancellation of polynomials
Authors: Zhong Xiao 
Published: August 2023

AbstractExtending the work of Bell, Matsuzawa and Satriano, we consider a finite set of polynomials over a number field and give a necessary and sufficient condition for the existence of an and a finite set such that for any , we have the cancellation result: If and are maps in such that , then in fact . Moreover, the conditions we give for this cancellation result to hold can be checked by a finite number of computations from the given set of polynomials.
Tensor stable moduli stacks and refined representations of quivers
Authors: Abdelgadir Tarig , Chan Daniel 
Published: August 2023

AbstractIn this paper, we look at the problem of modular realisations of derived equivalences, and more generally, the problem of recovering a Deligne–Mumford stack and a bundle on it, via some moduli problem (on or ). The key issue is, how does one incorporate some of the monoidal structure of into the moduli problem. To this end, we introduce a new moduli stack, the tensor stable moduli stack which generalises the notion of the Serre‐stable moduli stack. We then show how it can be used both for stack recovery and the modular realisation problem for derived equivalences. We also study the moduli of refined representations and how they address these problems. Finally, we relate the two approaches when is a tilting bundle which is a direct sum of line bundles.
Analytical Fractal Model for Effective Thermal Conductivity of Open-Cell Metallic Foams With Coated Hollow Ligaments
Authors: Xiao Tian , Lu Liu , Yu Chenlei , Boetcher Sandra K. S. , Yang Xiaohu , Li Moxiao , Lu Tian Jian 
Published: August 2023

Abstract
Coating the hollow ligaments of open-cell (fluid-through) metallic foams (MFs) fabricated via the sintering route with a thin layer of graphene can improve the effective thermal conductivity (ETC) of the foam without significantly increasing its flow resistance, potentially important for thermal storage applications. However, the Euclidean geometry cannot accurately depict the random distribution of pores within MFs. To this end, the present study aims to analyze how such thin coatings affect the ETC of MF by employing the fractal theory to depict the random distribution of its open pores. Subsequently, a cubic representative structure is chosen for self-similar pores in the fractal to establish a correlation between the geometric parameters of MF and its fractal dimension. Upon determining the thermal resistance provided a representative structure of the foam having coated hollow ligaments, its ETC is derived as a function of fractal dimension, dimensionless parameters of pore size, porosity, and thermal conductivity of relevant materials (e.g., ligaments, coatings, and filling medium). For validation, existing experimental data are used to compare with analytical predictions, with good agreement achieved. It is demonstrated that the ligament hollowness weakens the thermal conduction of MFs. In addition, when the coating has a thermal conductivity greater than that of ligament, the coating enhances the ability of the foam to conduct heat. Although the ligament hollowness and coating thickness are imperative factors affecting the ETC, the material makes of ligament and coating plays a decisive role in the ETC.
Agreement between the ventilated capsule and the KuduSmart® device for measuring sweating responses to passive heat stress and exercise
Authors: Ravanelli Nicholas , Newhouse Douglas , Foster Fergus , Caldwell Aaron R. 
Published: August 2023

The present study assessed agreement between a wireless sweat rate monitor (KuduSmart® device) and the ventilated capsule (VC) technique for measuring: (i) minute-averaged local sweat rate (LSR), (ii) sweating onset, (iii) sudomotor thermosensitivity, and (iv) steady-state LSR, during passive heat stress and exercise. It was hypothesized that acceptable agreement with no bias would be observed between techniques for all assessed sweating characteristics. On two separate occasions for each intervention, participants were either passively heated by recirculating hot water (49 °C) through a tube-lined garment until rectal temperature increased 1 °C over baseline ( n = 8), or a 60 min treadmill march at a fixed rate of heat production (∼500 W, n = 9). LSR of the forearm was concurrently measured with a VC and the KuduSmart® device secured within ∼2 cm. Using a ratio scale Bland–Altman analysis with the VC as the reference, the KuduSmart® device demonstrated systematic bias and not acceptable agreement for minute-averaged LSR (1.17 [1.09, 1.27], CV = 44.5%), systematic bias and acceptable agreement for steady-state LSR (1.16 [1.09,1.23], CV = 19.5%), no bias and acceptable agreement for thermosensitivity (1.07 [0.99, 1.16], CV = 23.2%), and no bias and good agreement for sweating onset (1.00 [1.00, 1.00], CV = 11.1%). In total, ≥73% of all minute-averaged LSR observations with the KuduSmart® device ( n = 2743) were within an absolute error of <0.2 mg/cm2/min to the VC, the reference minimum detectable change in measurement error of a VC on the forearm. Collectively, the KuduSmart® device may be a satisfactory solution for assessing the sweating response to heat stress where a VC is impractical.
The Role of Data Scientists in Modern Enterprises - Experience from Data Science Education
Authors: Mildenberger Thoralf , Braschler Martin , Ruckstuhl Andreas , Vorburger Robert , Stockinger Kurt 
Published: August 2023

"Data Scientist" has often been considered as the sexiest job of the 21st century. As a consequence, the spectrum of data science education programs has increased significantly in recent years, and there is a high demand for data scientists at many companies. However, what training is required to become a data scientist? What is the role of data scientists in current enterprises? Is the training well-aligned to the practical needs of a job?
In this article, we will address these questions by evaluating a survey of people who were trained in a continuing education program in data science in Switzerland. Our study sheds lights on the practical aspects of the data science education and how this newly-gained knowledge can successfully be applied in an enterprise. One of the highlights from the point of view of the database community is the important role of SQL in data science.
ІНДИВІДУАЛЬНИЙ ПРОГНОЗ ВИНИКНЕННЯ РЕЦИДИВУЮЧОГО ВІЗИНГУ В ДІТЕЙ ІЗ БРОНХІОЛІТОМ НА ОСНОВІ БАГАТОПОПУЛЯЦІЙНОЇ МОДЕЛІ ВЕЙБУЛЛА
Authors: Токарчук Н. І. , Очередько О. М. , Оверчук А. А. 
Published: August 2023

Мета дослідження – розробити моделі індивідуального прогнозу виникнення рецидивуючого візингу у дітей із бронхіолітом із врахуванням алергологічого анамнезу, пасивного тютюнокуріння, забезпечення вітаміном D, рівнів VCAM-1 та EDN.
Матеріали та методи. Основну групу склали 34 дитини, хворих на бронхіоліт без обтяженого алергологічного анамнезу. Групу порівняння становили 33 дитини, хворих на бронхіоліт із обтяженим алергологічним анамнезом. Аналітичний фрейм дослідження базувався на двопопуляційній моделі Вейбулла.
Результати дослідження та їх обговорення. Ризик рецидивуючого візингу у дітей, хворих на бронхіоліт за моделлю Вейбулла становили: алергологічний анамнез, β=679,57; пасивне тютюнокуріння, β=1114; проживання в міській місцевості, β=517,8; штучне вигодовування з β=767,3; дефіцит і недостатність вітаміну D, β=448,3; високі рівні VCAM-1 β=17,84 та EDN β=0,182.
Висновки. Підвищені рівні VCAM-1 та EDN виявились суттєвими маркерами прогнозу розвитку рецидивуючого візингу в дітей із бронхіолітом. Роль VCAM-1 є виключно важливою для створення прогнозу, оскільки саме за рівнем цього маркера визначається гетерогенність двох популяцій. Рівень EDN ≤ 7 нг/мл у сироватці крові є прогностичним маркером для ризику виникнення рецидивуючого візингу в дітей, хворих на бронхіоліт.