bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thermodynamics, kinetics and isothermal studies of tartrazine adsorption onto microcline/MWCNTs nanocomposite and the regeneration potentials
Authors: Amaku James Friday , Taziwa Raymond 
Published: June 2023

AbstractThe quest for a cheap, effective, and eco-friendly wastewater treatment technique that is free of secondary toxic byproducts, calls for the fabrication of a nature-friendly adsorbent with a robust capacity to decontaminate polluted water sources and be recycled. To this end, we report the fabrication of novel nanocomposite (KMCM) from microcline (KMC) and multiwall carbon nanotubes (MWCNTs). The adsorbents (KMC and KMCM) were characterized using XRD, BET, SEM, TGA and FTIR. The novel and low-cost nano sorbent were designed for the elimination of tartrazine (Tatz) from wastewater. The adsorption of Tatz onto KMC and KMCM was influenced by adsorbent dose, initial Tatz concentration, contact time and solution pH. Experimental data acquired from the equilibrium studies were well addressed by the Langmuir isotherm model. The maximum uptake capacity of 37.96 mg g−1 and 67.17 mg g−1 were estimated for KMC and KMCM. The kinetics for the adsorption of Tatz onto KMC and KMCM was best expressed by pseudo-second-order and Elovich models. The thermodynamic parameters revealed that the uptake of Tatz onto KMC and KMCM was an endothermic (ΔH: KMC = 35.0 kJ mol−1 and KMCM = 42.91 kJ mol−1), entropy-driven (ΔS: KMC = 177.6 J K−1 mol−1 and KMCM = 214.2 J K−1 mol−1) and spontaneous process. Meanwhile, KMCM demonstrated good reusability potential and superior adsorption efficiency when compared to other adsorbents.
Radiomics for characterization of the glioma immune microenvironment
Authors: Khalili Nastaran , Kazerooni Anahita Fathi , Familiar Ariana , Haldar Debanjan , Kraya Adam , Foster Jessica , Koptyra Mateusz , Storm Phillip B. , Resnick Adam C. , Nabavizadeh Ali 
Published: June 2023

AbstractIncreasing evidence suggests that besides mutational and molecular alterations, the immune component of the tumor microenvironment also substantially impacts tumor behavior and complicates treatment response, particularly to immunotherapies. Although the standard method for characterizing tumor immune profile is through performing integrated genomic analysis on tissue biopsies, the dynamic change in the immune composition of the tumor microenvironment makes this approach not feasible, especially for brain tumors. Radiomics is a rapidly growing field that uses advanced imaging techniques and computational algorithms to extract numerous quantitative features from medical images. Recent advances in machine learning methods are facilitating biological validation of radiomic signatures and allowing them to “mine” for a variety of significant correlates, including genetic, immunologic, and histologic data. Radiomics has the potential to be used as a non-invasive approach to predict the presence and density of immune cells within the microenvironment, as well as to assess the expression of immune-related genes and pathways. This information can be essential for patient stratification, informing treatment decisions and predicting patients’ response to immunotherapies. This is particularly important for tumors with difficult surgical access such as gliomas. In this review, we provide an overview of the glioma microenvironment, describe novel approaches for clustering patients based on their tumor immune profile, and discuss the latest progress on utilization of radiomics for immune profiling of glioma based on current literature.
Fourier synthesis dispersion engineering of photonic crystal microrings for broadband frequency combs
Authors: Moille Grégory , Lu Xiyuan , Stone Jordan , Westly Daron , Srinivasan Kartik 
Published: June 2023

AbstractDispersion engineering of microring resonators is crucial for optical frequency comb applications, to achieve targeted bandwidths and powers of individual comb teeth. However, conventional microrings only present two geometric degrees of freedom – width and thickness – which limits the degree to which dispersion can be controlled. We present a technique where we tune individual resonance frequencies for arbitrary dispersion tailoring. Using a photonic crystal microring resonator that induces coupling to both directions of propagation within the ring, we investigate an intuitive design based on Fourier synthesis. Here, the desired photonic crystal spatial profile is obtained through a Fourier relationship with the targeted modal frequency shifts, where each modal shift is determined based on the corresponding effective index modulation of the ring. Experimentally, we demonstrate several distinct dispersion profiles over dozens of modes in transverse magnetic polarization. In contrast, we find that the transverse electric polarization requires a more advanced model that accounts for the discontinuity of the field at the modulated interface. Finally, we present simulations showing arbitrary frequency comb spectral envelope tailoring using our Fourier synthesis approach.
Anisotropies of solar energetic electrons in the MeV range measured with Solar Orbiter/EPD/HET
Authors: Fleth S. , Kuehl P. , Kollhoff A. , Wimmer-Schweingruber R. F. , Heber B. , Rodríguez-Pacheco J. , Dresing N. 
Published: June 2023

Aims. This study analyses relativistic electron measurements obtained by the High Energy Telescope (HET) aboard Solar Orbiter in the energy range from 200 keV to above 10 MeV. Caveats of these measurements are discussed. The purpose of this study is to analyse anisotropies of relativistic solar energetic electrons utilising the different viewing directions of HET.
Methods. We identified time periods of interest, that is, those with enhanced electron flux due to a significant solar component, and composed a list of these time periods, including additional observations such as maximum energy and flux as well as the first-order anistropy.
Results. This study provides an overview of HET measurements of MeV electrons and a list of time periods of enhanced flux of relativistic solar electrons, 21 in total. For the first time with Solar Orbiter/EPD/HET, the anisotropies of high-energy electrons have been measured. Specifically, we find three time periods with significant anisotropy above 1 MeV within 0.5 au.
Central Serous Chorioretinopathy: An Update on the Current State of Management
Authors: Kalogeropoulos Dimitrios , Shaw Lincoln , Skondra Dimitra , Ch'ng Soon Wai , Christodoulou Aikaterini , Kalogeropoulos Chris 
Published: June 2023

AbstractCentral serous chorioretinopathy (CSCR) is a relatively common retinal disorder that leads to central vision impairment, often with a high recurrence rate. The exact etiology and pathogenetic mechanisms have not been fully elucidated but are likely to be associated with hyperpermeability of the choroidal capillaries and failure of the retinal pigment epithelium (RPE), leading to serous detachment of the neurosensory retina. Multimodal imaging plays a critical role in the diagnostic approach and monitoring of CSCR. Fortunately, the natural course of the disease is usually self-limiting, with spontaneous resolution and total fluid reabsorption. However, some patients may exhibit recurrences or persistent subretinal fluid (chronic CSCR), leading to progressive and irreversible RPE atrophy or photoreceptor damage. Thus, to prevent permanent visual loss, individualized treatment should be considered. Recent developments in the diagnostic and therapeutic approach have contributed
to better outcomes in patients with CSCR. More studies are required to improve our understanding of epidemiology, pathogenesis, diagnosis, and treatment, with a significant impact on the management of this challenging clinical entity. The purpose of this review is to summarize the current knowledge about the clinical features, diagnostic workup, and therapeutic approach of CSCR.
Development, validation, and results of a national endoscopy safety attitudes questionnaire (Endo-SAQ)
Authors: Ravindran Srivathsan , Matharoo Manmeet , Marshall Sarah , Robinson Emma , Bano Madeline , Bassett Paul , Coleman Mark , Rutter Matt , Ashrafian Hutan , Darzi Ara , Healey Chris , Thomas-Gibson Siwan 
Published: June 2023

Abstract
Background and study aims Safety attitudes are linked to patient outcomes. The Joint Advisory Group on Gastrointestinal Endoscopy (JAG) identifies the need to improve our understanding of safety culture in endoscopy. We describe the development and validation of the Endo-SAQ (endoscopy safety attitudes questionnaire) and the results of a national survey of staff attitudes.
Methods Questions from the original SAQ were adapted to reflect endoscopy-specific content. This was refined by an expert group, followed by a pilot study to assess acceptability. The refined Endo-SAQ (comprising 35 questions across six domains) was disseminated to endoscopy staff across the UK and Ireland. Outcomes were domain scores and the percentage of positive responses (score ≥75/100) per domain. Descriptive and comparative analyses were performed. Binary logistic regression identified staff and service factors associated with positive scores. Validity and reliability of Endo-SAQ were assessed through psychometric analysis.
Results After expert review, four questions in the preliminary Endo-SAQ were adjusted. Sixty-one participants undertook the pilot study with good acceptability. A total of 453 participants completed the refined Endo-SAQ. There were positive responses in teamwork, safety climate, job satisfaction, and working conditions domains. Endoscopists had significantly more positive responses to stress recognition and working conditions than nursing staff. JAG accreditation was associated with positive scores in safety climate and job satisfaction domains. Endo-SAQ met thresholds of construct validity and reliability.
Conclusions Endoscopy staff had largely positive safety attitudes scores but there were significant differences across domains and staff. There is evidence for the validity and reliability of Endo-SAQ. Endo-SAQ could complement current measures of patient safety in endoscopy and be used in evaluation and research.
Perforation-free removal of gastric gastrointestinal stromal tumors: Endoscopic inversion and strangulation of muscle layer and resection (EISMR)
Authors: Yamashina Takeshi , Shimatani Masaaki , Matsumoto Hironao , Orino Masahiro , Kano Masataka , Kasai Takeshi , Saito Natsuko , Horitani Shunsuke , Mitsuyama Toshiyuki , Sumimoto Kimi , Takeo Masahiro , Yuba Takafumi , Naganuma Makoto 
Published: June 2023

AbstractEndoscopic resection for GIST has become more widespread in recent years because it is less invasive than surgery. However, when endoscopic resection is performed, a full-layer resection of the gastric wall is often necessary, and extensive suturing is required if perforation occurs, which is a technically challenging procedure. Recently, we reported a new method called endoscopic inversion and strangulation of the muscle layer and resection (EISMR), which consists of endoscopically inverting the muscle layer into the gastric lumen and strangulating the muscle layer with a detachable snare, followed by resection.The study comprised five consecutive patients with gastric GIST ≤50 mm in diameter who underwent EISMR procedures. The main outcomes of the study were en bloc resection rate, R0 resection rate, procedure time, and complications. The results showed that all five patients successfully underwent complete resection without perforation, and the en bloc resection and R0 resection rates were 100%. The median procedure time was 93 min (range, 58–120 min), and there were no major complications. We concluded that EISMR would be a safe and effective technique for endoscopic resection of gastric GISTs and may be an alternative to surgery or endoscopic submucosal dissection.
Effects of Body Weight Support in Running on Achilles Tendon
Loading
Authors: Pohlman Callie , Pardee Andrew , Friedman Mikey , Rutherford Drew , Vannatta Charles Nathan , Kernozek Thomas W. 
Published: June 2023

AbstractAchilles tendon (AT) tendinopathy is common in runners. Repetitive AT loading may
play a role in etiology. Interventions such as body weight support (BWS) may
reduce loading on the AT in running. Examine how ground reaction force, AT
loading, foot strike, and cadence variables change in running with BWS.
Twenty-four healthy female runners free from injury were examined. Participants
ran on an instrumented treadmill with and without BWS using a harness-based
system at a standardized speed. The system has 4 elastic cords affixed to a
harness that is attached to a frame-like structure. Kinematic data and kinetic
data were used in a musculoskeletal model (18 segments and 16 degrees of
freedom) to determine AT loading variables, foot strike angle, and cadence.
Paired t-tests were used to compare each variable between conditions. Ground
reaction force was 9.0% lower with BWS (p<.05). Peak AT stress,
force, and impulse were 9.4, 11.7%, and 14.8% lower when using
BWS in running compared to no support (p<.05). Foot strike angle was
similar (p<.05) despite cadence being reduced (p<.05). BWS may
reduce AT loading and impulse variables during running. This may be important in
rehabilitation efforts.
Role of CBCT in Prediction of Oro-antral Communication Post Third Molar Extraction: A Retrospective Study
Authors: Singh Anupam , Kodali Murali Venkata Rama Mohan , Pentapati Kalyana Chakravarthy , Chattopadhyay Anwesha , Shetty Rhea , Patil Vathsala , Gadicherla Srikanth , Smriti Komal 
Published: June 2023

AbstractObjective Oro-antral communication (OAC) is one of the most frequently encountered complications during third molar extraction. Various radiographic factors, like excessive maxillary sinus pneumatization, long periods of edentulism, periapical lesions, etc., have been considered high-risk factors for OAC. However, a panoramic radiograph has not proven to be accurate in predicting the chances of OAC. Through this retrospective study, we evaluated the efficacy of a CBCT in predicting the incidence of OAC after maxillary third molar extraction.Materials and Methods We conducted a retrospective study in our department, which included the patients who had undergone extraction of a maxillary third molar over five years with the presence of panoramic X-rays and/or CBCT scans prior to extraction. Primary outcomes assessed from the case files were intra-operative complications like OAC, root fracture, tuberosity fracture, pterygoid plate fracture, etc. The incidence of these complications was correlated with the presence or absence of CBCT before extraction.Results Out of 920 extracted maxillary third molar, only 148 teeth (16.1%) had a CBCT record before extraction. The most commonly encountered complication was broken inaccessible root piece/s (4.9%), followed by OAC (3.5%). An inter-group comparison showed that a significantly higher percentage of patients (p < 0.001) with CBCT records had an incidence of OAC (11.5%) as against the group of patients with no CBCT record (1.9%).Conclusion A CBCT scan prior to cases with high-risk factors for OAC can be a valuable tool in accurately predicting the chances of OAC after maxillary third molar extraction.
Surgical Techniques for the Management of Placenta Accreta Spectrum
Authors: Khoury-Collado Fady , Newton J. M. , Brook Olga R. , Carusi Daniela A. , Shrivastava Vineet K. , Crosland Brian A. , Fox Karin A. , Khandelwal Meena , Karam Amer K. , Bennett Kelly A. , Sandlin Adam T. , Shainker Scott A. , Einerson Brett D. , Belfort Michael A. ,   for the Pan-American Society for Placenta Accreta Spectrum
Published: June 2023

The surgical management of placenta accreta spectrum (PAS) is often challenging. There are a variety of techniques and management options described in the literature ranging from uterine sparing to cesarean hysterectomy. Following the inaugural meeting of the Pan-American Society for Placenta Accreta Spectrum a multidisciplinary group collaborated to describe collective recommendations for the surgical management of PAS. In this manuscript, we outline individual components of the procedure and provide suggested direction at key points of a cesarean hysterectomy in the setting of PAS.
Key Points
Critical Care in Placenta Accreta Spectrum Disorders—A Call to Action
Authors: Padilla Cesar R. , Shamshirsaz Amir A. , Easter Sarah R. , Hess Phillip , Smith Carly , El Sharawi Nadir , Sandlin Adam T. 
Published: June 2023

The rising in placenta accreta spectrum (PAS) incidence, highlights the need for critical care allotment for these patients. Due to risk for hemorrhage and possible hemorrhagic shock requiring blood product transfusion, hemodynamic instability and risk of end-organ damage, having an intensive care unit (ICU) with surgical expertise (surgical ICU or equivalent based on institutional resources) is highly recommended. Intensive care units physicians and nurses should be familiarized with intraoperative anesthetic and surgical techniques as well as obstetrics physiologic changes to provide postpartum management of PAS. Validated tools such of bedside point of care ultrasound and viscoelastic tests such as thromboelastogram/rotational thromboelastometry (TEG/ROTEM) are clinically useful in the assessment of hemodynamic status (shock diagnosis, assessment of both fluid responsiveness and tolerance) and transfusion guidance (in patients requiring massive transfusion as opposed to tranditional hemostatic resuscitation) respectively. The future of PAS management lies in the collaborative and multidisciplinary environment. We recommend that women with high suspicion or a confirmed PAS should have a preoperative plan in place and be managed in a tertiary center who is experienced in managing surgically complex cases.
Key Points
Can a Mother's Parenting Style Predict Adolescent Oral Hygiene Behavior? A Self-Reported Cross-Sectional Study
Authors: Annisa Deva , Abidin Fitri Ariyanti , Setiawan Arlette Suzy 
Published: June 2023

Abstract
Objective Adolescent oral hygiene behavior plays a crucial role into adulthood and still requires attention from parents, especially mothers. Parenting done by the mother will directly affect the child's life, including the child's oral hygiene behavior. The aim of this study was to determine the role of the mother's parenting style in predicting adolescent oral hygiene behavior.
Materials and Methods A quantitative study with a cross-sectional approach was used to examine the role of parenting style on their teenage child's oral hygiene behavior. The instruments used were (1) a parenting style measuring instrument to measure supportive and nonsupportive parenting styles of mothers (parent as social context questionnaire) and (2) a self-structured oral hygiene behavior measuring instrument based on the theory of planned behavior. The population of this study were students at SMP PGRI Depok and SMP Negeri 11 Depok, West Java, aged between 12 and 14 years. The sampling technique used total sampling on SMP PGRI students and multistage random sampling on students at SMP Negeri 11 Depok with a total sample of 230 students. Data analysis was done using multiple linear regression test.
Results Statistical regression tests showed that nonsupportive parenting style did not predict adolescent oral hygiene behavior (p = 0.567), while supportive parenting style did predict adolescent oral hygiene behavior (p = 0.000). Supportive parenting style predicts 31.2% of adolescent oral hygiene behavior.
Conclusion Mother's supportive parenting style plays a role in predicting adolescent oral hygiene, and the mother's nonsupportive parenting style does not play a role in predicting adolescent oral hygiene behavior.
The Effect of Dental Implant Drills Materials on Heat Generation in Osteotomy Sites: A Systematic Review
Authors: Chakraborty Shreyasi , Moufti Mohammad-Adel , Kheder Waad 
Published: June 2023

AbstractThe aim of this review was to examine the impact of dental implant drill materials and wear profiles on heat generation in the osteotomy sites as reported in experimental studies and to critically appraise these studies. The research question was formulated based on predefined patient, intervention, comparison, and outcome (PICO) elements. A comprehensive electronic search was undertaken in Medline/PubMed Central, Science Direct, and Google Scholar, using predetermined keywords, followed by a manual search of the bibliography of the selected articles. The selection of the studies for the critical appraisal part of our study was based on the criteria used to assess the study designs such as study aims, outcome measure, clarity of method, sample selection, randomization, allocation concealment, sample attrition, bias, method of data analysis, and external validity. Increased heat generation was observed with both ceramic and metal drills; the heat generation was proportional to drills' wear. The literature was inconclusive regarding the association between drill material and heat generation. However, drill materials had a significant influence on the overall temperature increase during osteotomy. The noncoated drills showed a higher wear resistance, and it has been observed that using worn drills leads to more friction contact, reduced drill cutting efficiency, and increased heat generation. Eleven in vitro studies met the inclusion criteria, and showed a considerable methodological heterogeneity and confounding factors, including drill geometry, speed and load, depth and diameter, number of uses, irrigation protocol, study specimens, and the heat measuring device. Besides, most of the studies have a potential operator and assessor bias, and some have sponsorship bias. It is possible to conclude that the literature is not conclusive on the effect of drill materials on heat generation during osteotomy. Lack of standardization and uniformity in the study design, along with potential bias in the study methodology can be the reason for the heterogeneity of the results.
The Wholesome Foods Approach to Trabeculectomy Wet Lab Training
Authors: Gallant Tara L. , Lieng Monica K. , Rizzo Jennifer L. , Brandt James D. , Lim Michele C. 
Published: June 2023

Abstract
Purpose In an era when trabeculectomy surgeries in the United States are on the decline, ophthalmology residents may have limited opportunities to practice surgical techniques critical to success. However, key steps of trabeculectomy surgery can be introduced in a wet laboratory using a simple surgical model based on food items.
Methods A fresh lime and chicken parts with skin, purchased from a grocery store, were utilized to practice trabeculectomy surgery. The white rind of a lime was used as a surrogate for human sclera and was incised to create a trabeculectomy flap. The flap was then successfully sewn down with 10–0 nylon suture using an operating microscope. The skin of the chicken part was used to re-create a fornix-based and limbus-based conjunctival incision, which was then sutured closed using 6–0 Vicryl suture. A survey of wet laboratory participants was conducted to assess the feasibility and efficacy of this technique.
Results Survey respondents were divided into two groups, those who had performed ≥40 incisional glaucoma surgeries and those who had performed <40. Both groups rated the simulation a 4 (mode) out of 5 in terms of how well it prepared them for glaucoma surgery on a human eye and how well the materials replicated human tissue, with 1 being not at all and 5 being very well. Similarly, both groups rated ease of setup and material acquisition a 1 out of 5, 1 being not difficult at all and 5 being extremely difficult. Also, 93.5% of the survey respondents recommended implementing this training model at other teaching hospitals, and none of the respondents recommended against it.
Conclusion This trabeculectomy teaching model is inexpensive, clean, and safe, and it provides a reasonably realistic substrate for surgical practice. It does not require cadaver or animal eyes, and no fixatives are needed, thus minimizing the risk of contact with biohazardous materials. Wet laboratory materials are easy to obtain, making this a practical model for practicing glaucoma surgery in both westernized and developing countries.