bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of the coronavirus pandemic on perceived capitalization support provision and receipt
Authors: Gosnell Courtney L. , Dascano Kendra 
Published: June 2023

AbstractThe coronavirus pandemic has influenced relationship dynamics due to heightened stress, increased isolation, and the need for social distancing. Prior work suggests receiving support for positive events (“capitalization support”) during this time could boost well‐being, but only if it is provided in a manner that is active (involved) and constructive (supportive), as opposed to passive (uninvolved) and/or destructive (discouraging). Given the need for reduced social contact, we predicted the pandemic would make providing active, constructive support more challenging and might increase the frequency of passive support. We conducted two studies to explore how perceptions of capitalization methods may have shifted during the pandemic using an online participant pool (MTurk). Overall, we found that participants reported receiving significantly less active‐constructive capitalization support and receiving more passive‐constructive support during the pandemic (compared to pre‐pandemic perceptions). In addition, we found that those who reported receiving and providing more active‐constructive support tended to report more positive well‐being outcomes. Interestingly, passive‐constructive support was also associated with greater well‐being for recipients (counter to prior research that has shown it associated with only costs). Overall, our data suggests that capitalization support perceptions are associated with well‐being even during the pandemic, but methods of capitalization support perceived may have shifted during the pandemic.
VPT‐like genes modulate Rhizobium–legume symbiosis and phosphorus adaptation
Authors: Liu Jinlong , Yang Rongchen , Yan Jun , Li Chun , Lin Xizhen , Lin Lin , Cao Yanyan , Xu Tiandong , Li Jianxuan , Yuan Yangyang , Wen Jiangqi , Mysore Kirankumar S. , Luan Sheng 
Published: June 2023

SUMMARYAlthough vacuolar phosphate transporters (VPTs) are essential for plant phosphorus adaptation, their role in Rhizobium–legume symbiosis is unclear. In this study, homologous genes of VPT1 (MtVPTs) were identified in Medicago truncatula to assess their roles in Rhizobium–legume symbiosis and phosphorus adaptation. MtVPT2 and MtVPT3 mainly positively responded to low and high phosphate, respectively. However, both mtvpt2 and mtvpt3 mutants displayed shoot phenotypes with high phosphate sensitivity and low phosphate tolerance. The root‐to‐shoot phosphate transfer efficiency was significantly enhanced in mtvpt3 but weakened in mtvpt2, accompanied by lower and higher root cytosolic inorganic phosphate (Pi) concentration, respectively. Low phosphate induced MtVPT2 and MtVPT3 expressions in nodules. MtVPT2 and MtVPT3 mutations markedly reduced the nodule number and nitrogenase activity under different phosphate conditions. Cytosolic Pi concentration in nodules was significantly lower in mtvpt2 and mtvpt3 than in the wildtype, especially in tissues near the base of nodules, probably due to inhibition of long‐distance Pi transport and cytosolic Pi supply. Also, mtvpt2 and mtvpt3 could not maintain a stable cytosolic Pi level in the nodule fixation zone as the wildtype under low phosphate stress. These findings show that MtVPT2 and MtVPT3 modulate phosphorus adaptation and rhizobia–legume symbiosis, possibly by regulating long‐distance Pi transport.
The Arabidopsis RRM domain proteins EDM3 and IBM2 coordinate the floral transition and basal immune responses
Authors: Wang Jianqiang , Eulgem Thomas 
Published: June 2023

SUMMARYThe transition from vegetative to reproductive development (floral transition) is a costly process in annual plants requiring increased investments in metabolic resources. The Arabidopsis thaliana (Arabidopsis) PHD finger protein EDM2 and RRM domain proteins EDM3 and IBM2 are known to form chromatin‐associated complexes controlling transcript processing. We are reporting that distinct splice isoforms of EDM3 and IBM2 cooperate in the coordination of the floral transition with basal immune responses. These cooperating splice isoforms, termed EDM3L and IBM2L, control the intensity of basal immunity and, via a separate pathway, the timing of the floral transition. During the developmental phase prior to the floral transition expression of EDM3L and IBM2L strongly and gradually increases, while these isoforms simultaneously down‐regulate expression of the floral suppressor gene FLC and promote the transition to reproductive growth. At the same time these accumulating EDM3 and IBM2 splice isoforms gradually suppress basal immunity against the virulent Noco2 isolate of the pathogenic oomycete Hyaloperonospora arabidopsidis and down‐regulate expression of a set of defense‐associated genes and immune receptor genes. We are providing clear evidence for a functional link between the floral transition and basal immunity in the annual plant Arabidopsis. Coordination of these two biological processes, which compete for metabolic resources, is likely critical for plant survival and reproductive success.
K3 surfaces with action of the group M20$M_{20}$
Authors: Comparin Paola , Demelle Romain 
Published: June 2023

AbstractIt was shown by Mukai that the maximum order of a finite group acting faithfully and symplectically on a K3 surface is 960 and if such a group has order 960, then it is isomorphic to the Mathieu group . In this paper, we are interested in projective K3 surfaces admitting a faithful symplectic action of the group . We show that there are infinitely many K3 surfaces with this action and we describe them and their projective models, giving some explicit examples.
Nonlinear Thermal-Magneto-Mechanical Vibration Analysis of Single-Walled Embedded Branched Carbon Nanotubes Conveying Nanofluid
Authors: Yinusa A. A. , Sobamowo M. G. 
Published: June 2023

Abstract
In this present study, the nonlinear thermal-magneto-mechanical stability and vibration of branched nanotube conveying nano-magnetic fluid embedded in linear and nonlinear elastic foundations are analyzed. The governing equations are established via Euler–Bernoulli theory, Hamilton’s principle, and the nonlocal theory of elasticity. The fluid flow and thermal behaviors of the nanofluid are described using modified Navier–Stokes and conservation of energy equations. With the aid of the Galerkin decomposition technique and differential transformation method (DTM), the coupled thermos-fluidic-vibration equation is solved analytically. The analytical solutions as presented in this study match with an existing experimental result and as such used to explore the influences of nonlocal parameters, downstream or branch angle, temperature, magnetic effect, fluid velocity, foundation parameters, and end conditions on vibrations of the nanotube. The results indicate that decreasing temperature change and augmenting the nanotube branch angle decreases the stability for the prebifurcation domain but increases for the post-bifurcation region. Furthermore, the magnetic term possesses a damping or an attenuating impact on the nanotube vibration response at any mode and for any boundary condition considered. It is anticipated that the outcome of this present study will find applications in the strategic optimization of designed nano-devices under thermo-mechanical flow-induced vibration.
Simplified sewerage to prevent urban leptospirosis transmission: a cluster non-randomised controlled trial protocol in disadvantaged urban communities of Salvador, Brazil
Authors: Cremonese Cleber , Souza Fabio Neves , Palma Fabiana Almerinda Gonçalves , Sodré Jonatas Fernandes Araújo , Brito Ricardo Lustosa , Ribeiro Priscyla dos Santos , Santana Juliet Oliveira , Coelho Rachel Helena , Ticona Juan P Aguilar , Nazaré Romero J , de Oliveira Daiana , Silva Cainã Queiroz , Eyre Max T , Mendes Vinícius de Araújo , Knee Jackie , Ristow Paula , Stauber Christine E , López Yeimi Alexandra Alzate , Giorgi Emanuele , Diggle Peter J , Reis Mitermayer Galvão G , Cumming Oliver , Ko Albert , Costa Federico 
Published: June 2023

IntroductionLeptospirosis is a globally distributed zoonotic and environmentally mediated disease that has emerged as a major health problem in urban slums in developing countries. Its aetiological agent is bacteria of the genusLeptospira, which are mainly spread in the urine of infected rodents, especially in an environment where adequate sanitation facilities are lacking, and it is known that open sewers are key transmission sources of the disease. Therefore, we aim to evaluate the effectiveness of a simplified sewerage intervention in reducing the risk of exposure to contaminated environments andLeptospirainfection and to characterise the transmission mechanisms involved.Methods and analysisThis matched quasi-experimental study design using non-randomised intervention and control clusters was designed to assess the effectiveness of an urban simplified sewerage intervention in the low-income communities of Salvador, Brazil. The intervention consists of household-level piped sewerage connections and community engagement and public involvement activities. A cohort of 1400 adult participants will be recruited and grouped into eight clusters consisting of four matched intervention-control pairs with approximately 175 individuals in each cluster in baseline. The primary outcome is the seroincidence ofLeptospirainfection assessed through five serological measurements: one preintervention (baseline) and four postintervention. As a secondary outcome, we will assessLeptospiraload in soil, before and after the intervention. We will also assessLeptospiraexposures before and after the intervention, through transmission modelling, accounting for residents' movement, contact with flooding, contaminated soil and water, and rat infestation, to examine whether and how routes of exposure forLeptospirachange following the introduction of sanitation.Ethics and disseminationThis study protocol has been reviewed and approved by the ethics boards at the Federal University of Bahia and the Brazilian National Research Ethics Committee. Results will be disseminated through peer-reviewed publications and presentations to implementers, researchers and participating communities.Trial registration numberBrazilian Clinical Trials Registry (RBR-8cjjpgm).
What is the landscape of evidence about the safety of physical agents used in physical medicine and rehabilitation? A scoping review
Authors: Bargeri Silvia , Pellicciari Leonardo , Gallo Chiara , Rossettini Giacomo , Castellini Greta , Gianola Silvia 
Published: June 2023

BackgroundSeveral systematic reviews (SRs) assessing the effectiveness of superficial physical agents have been published, but the evidence about their safety remains controversial.ObjectiveTo identify areas where there is evidence of the safety of physical agents by a scoping review.DesignFour databases were systematically searched for including English SRs that explored and reported safety in terms of adverse events (AEs) related to the application of physical agents in outpatient and inpatient physical medicine and rehabilitation settings managed by healthcare professionals, published in January 2011–29 September 2021. The severity of AEs was classified according to the Common Terminology Criteria. Then, AE findings were summarised according to the SR syntheses. Finally, the reporting of the certainty of the evidence was mapped.ResultsOverall, 117 SRs were retrieved. Most of the SRs included randomised controlled trials (77%) and patients with musculoskeletal disorders (67%). The most investigated physical agents were extracorporeal shock wave therapy (ESWT) (15%), transcutaneous electrical nerve stimulation (13%) and electrical stimulation (12%). No AE (35%) was reported in one-third of the included primary studies in SRs, whereas few severe AEs occurred in less than 1% of the sample. Among physical agents, ESWT showed an increased risk of experiencing mild AEs compared with the control. Most SRs reported a qualitative AE synthesis (65.8%), and few reported the certainty of the evidence (17.9%), which was mainly low.ConclusionWe found evidence of safety on several physical agents coming mostly from qualitative synthesis. No significant harms of these interventions were found except for ESWT reporting mild AEs. More attention to the AEs reporting and their classification should be pursued to analyse them and assess the certainty of evidence quantitatively.Review registrationhttps://osf.io/6vx5a/.
Cohort profile: rationale and methods of UK Biobank repeat imaging study eye measures to study dementia
Authors: Foster Paul J , Atan Denize , Khawaja Anthony , Lotery Andrew , MacGillivray Tom , Owen Christopher G , Patel Praveen J , Petzold Axel , Rudnicka Alicja , Sun Zihan , Sheard Simon , Allen Naomi 
Published: June 2023

PurposeThe retina provides biomarkers of neuronal and vascular health that offer promising insights into cognitive ageing, mild cognitive impairment and dementia. This article described the rationale and methodology of eye and vision assessments with the aim of supporting the study of dementia in the UK Biobank Repeat Imaging study.ParticipantsUK Biobank is a large-scale, multicentre, prospective cohort containing in-depth genetic, lifestyle, environmental and health information from half a million participants aged 40–69 enrolled in 2006–2010 across the UK. A subset (up to 60 000 participants) of the cohort will be invited to the UK Biobank Repeat Imaging Study to collect repeated brain, cardiac and abdominal MRI scans, whole-body dual-energy X-ray absorptiometry, carotid ultrasound, as well as retinal optical coherence tomography (OCT) and colour fundus photographs.Findings to dateUK Biobank has helped make significant advances in understanding risk factors for many common diseases, including for dementia and cognitive decline. Ophthalmic genetic and epidemiology studies have also benefited from the unparalleled combination of very large numbers of participants, deep phenotyping and longitudinal follow-up of the cohort, with comprehensive health data linkage to disease outcomes. In addition, we have used UK Biobank data to describe the relationship between retinal structures, cognitive function and brain MRI-derived phenotypes.Future plansThe collection of eye-related data (eg, OCT), as part of the UK Biobank Repeat Imaging study, will take place in 2022–2028. The depth and breadth and longitudinal nature of this dataset, coupled with its open-access policy, will create a major new resource for dementia diagnostic discovery and to better understand its association with comorbid diseases. In addition, the broad and diverse data available in this study will support research into ophthalmic diseases and various other health outcomes beyond dementia.
Predictive ability of pulse oximetry-derived indices for hypotension after spinal anaesthesia for caesarean section: protocol for a systematic review and meta-analysis
Authors: Kondo Yuriko , Mihara Takahiro , Nakamura Eishin , Noma Hisashi , Shimizu Sayuri , Goto Takahisa 
Published: June 2023

IntroductionIn general, caesarean sections are performed under spinal anaesthesia. Hypotension after spinal anaesthesia adversely affects both the mother and fetus. Although several studies have used pulse oximetry-derived indices, such as pulse perfusion index (PI) and Pleth variability index (PVI), to predict hypotension after spinal anaesthesia, the predictive ability of the PI and PVI remain controversial.Methods and analysisWe prepared this protocol following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols guidelines. We will conduct searches of MEDLINE, Embase, Web of Science, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Clinicaltrial.gov, European Union Clinical Trials Register (EU-CTR), WHO International Clinical Trials Registry Platform (ICTRP) and University Hospital Medical Information Network Clinical Trials Registry (UMIN) from inception until 8 October 2022. We will include retrospective and prospective observational studies and randomised controlled trials that evaluated the predictive ability of PI and PVI for hypotension after spinal anaesthesia for caesarean section, published in any language. We will exclude case reports, case series and animal studies. Two authors will independently scan and select eligible studies and perform data extraction and assessment of risk of bias. We will estimate predictive ability of PI and PVI as indices of hypotension after spinal anaesthesia for caesarean section using the Reitsma-type bivariate random-effects synthesis model and the hierarchical summary receiver operating characteristic curve. We will assess the quality of evidence using the Grading of Recommendation Assessment, Development and Evaluation approach.Ethics and disseminationEthics approval is not required as the systematic review will use existing published data. The results will be submitted for publication in a peer-reviewed journal.PROSPERO registration numberCRD42022362596.
Child Developmental MRI (CDM) project: protocol for a multi-centre, cross-sectional study on elucidating the pathophysiology of attention-deficit/hyperactivity disorder and autism spectrum disorder through a multi-dimensional approach
Authors: Yamashita Masatoshi , Kagitani-Shimono Kuriko , Hirano Yoshiyuki , Hamatani Sayo , Nishitani Shota , Yao Akiko , Kurata Sawa , Kosaka Hirotaka , Jung Minyoung , Yoshida Tokiko , Sasaki Tsuyoshi , Matsumoto Koji , Kato Yoko , Nakanishi Mariko , Tachibana Masaya , Mohri Ikuko , Tsuchiya Kenji J , Tsujikawa Tetsuya , Okazawa Hidehiko , Shimizu Eiji , Taniike Masako , Tomoda Akemi , Mizuno Yoshifumi 
Published: June 2023

IntroductionNeuroimaging studies on attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) have demonstrated differences in extensive brain structure, activity and network. However, there remains heterogeneity and inconsistency across these findings, presumably because of the diversity of the disorders themselves, small sample sizes, and site and parameter differences in MRI scanners, and their overall pathogenesis remains unclear. To address these gaps in the literature, we will apply the travelling-subject approach to correct site differences in MRI scanners and clarify brain structure and network characteristics of children with ADHD and ASD using large samples collected in a multi-centre collaboration. In addition, we will investigate the relationship between these characteristics and genetic, epigenetic, biochemical markers, and behavioural and psychological measures.Methods and analysisWe will collect resting-state functional MRI (fMRI) and T1-weighted and diffusion-weighted MRI data from 15 healthy adults as travelling subjects and 300 children (ADHD, n=100; ASD, n=100; and typical development, n=100) with multi-dimensional assessments. We will also apply data from more than 1000 samples acquired in our previous neuroimaging studies on ADHD and ASD.Ethics and disseminationThe study protocol has been approved by the Research Ethics Committee of the University of Fukui Hospital (approval no: 20220601). Our study findings will be submitted to scientific peer-reviewed journals and conferences.
Women’s lived experiences of sex hormones and life-related to bariatric surgery: an interpretative qualitative study
Authors: Paul Rebecca , Andersson Ellen , Olbers Torsten , Frisk Jessica , Berterö Carina M 
Published: June 2023

ObjectivesThe study aimed to explore the lived experiences of women with severe obesity before and after undergoing bariatric surgery with a special focus on possible effects of changed sex hormone levels.DesignA qualitative interview study with transcribed text analysis based on Gadamer’s hermeneutics.SettingRegional hospital and outpatient bariatric clinic in central Sweden.ParticipantsTen women (age 23–38 years) having undergone Roux-en-Y gastric bypass surgery between 2016 and 2019 were interviewed.ResultsThe transcribed interviews were analysed according to Gadamer’s hermeneutics. Text horizons, interpreter horizons and fact horizons were derived and formed the fusions ‘Recognition of unhealthy body weight’, ‘Dealing with other people’s opinions and society’s norms’, ‘Life has changed in a positive way’ and ‘Accepting inner self and bodily changes’.ConclusionWomen highlighted weight and body size in their responses. The study provided a deeper understanding of the situation of women living with obesity and pros and cons of having undergone bariatric surgery. Experiences of changes in sex hormones and fertility were discussed but not central to the informants. Participants emphasised the need to be prepared and properly supported in dealing with changes in life after bariatric surgery and subsequent weight loss.
Infants’ immunisations, their timing and the risk of allergic diseases (INITIAL): an observational prospective cohort study protocol
Authors: Wrenger Jennifer , Martin David D , Jenetzky Ekkehart 
Published: June 2023

IntroductionVaccinations are considered to have a large impact on disease control, hence a multitude of vaccines in infancy is recommended. Retrospective studies suggest a possible relation between timing, kind or number of vaccines given in the first year of life and the subsequent incidence of allergic diseases. It must be clarified whether a causal relationship exists to ensure safety and reduce vaccine hesitancy.Methods and analysisDue to the high recommendation rate of vaccines, a long-term randomised controlled trial is not considered as ethically acceptable. Therefore, this study aims to observe prospectively the allergic incidence at the age of 5 years after various vaccine interventions in the early months of life.Parents of infants up to the age of 4–6 weeks will be recruited before the first recommended vaccination. Relevant prognostic factors for allergies, status of immunisation and general health will be evaluated up to the age of 5.Allergic symptoms will be assessed by the International Study of Asthma and Allergies in Childhood-questionnaire and a medical confirmation of the allergy is mandatory.The main objective is to compare the incidence of asthma, atopic dermatitis, rhinoconjunctivitis, food allergy or any of these atopies at the age of 5 between infants who were not vaccinated or were vaccinated according to recommendations in the first year of life.The sample size calculation with about 4000 participants can prove a 5% difference to the basic prevalence with about 80% power and global 5% alpha error for the five primary endpoints adjusting according to Bonferroni-Holm and assuming a rate of 10% not early vaccinated infants.Ethics and disseminationThe study was registered (DRKS00029677) and has received approval by the ethics committee of Universität Witten/Herdecke (no. 113/2022). The results will be published.