bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of dietary pretreated Chinese herbal medicine supplementation on production performance, egg quality, uterine histopathological changes, and antioxidant capacity in late-phase laying hens
Authors: Yu Ao-Chuan , Wang Min-An , Chen Li , Long Cheng , Guo Yong , Sheng Xi-Hui , Wang Xiang-Guo , Xing Kai , Xiao Long-Fei , Ni He-Min , Li Jian-Tao , Qi Xiao-Long 
Published: January 2023

Aims: The study aimed to evaluate the effects of pretreated Chinese herbal medicine (PCHM) on egg quality, production performance, histopathological changes in the uterus, antiox idant capacity, and antioxidant gene expression in late-phase layers.Methods: Jinghong No.1 layers (n = 360, 68 weeks old) were assigned randomly to one of f our dietary interventions. Each treatment was replicated six times. Repeat 15 chickens per g roup. All birds were fed a diet composed of a corn-soybean meal-based diet supplemented with 0, 0.2, 0.4, or 0.8% PCHM for 6 weeks.Results: Dietary PCHM supplementation had no significant effects on laying rate, feed con sumption, yolk color, and shape index. With increasing PCHM level the Haugh unit linearly increased (P &lt; 0.05). Supplementation of 0.8% PCHM increased egg weight, compared with the control (P &lt; 0.05). PCHM can effectively alleviated the pathological changes caused by aging in the uterus including hemorrhage, and many inflammatory cell infiltrations. Supplementation of 0.4% PCHM increased glutathione peroxidase (GSHPx) in liver, magnum, and plasm considerably, compared with the control (P &lt; 0.05). Supplementation of PCHM decr ease in the liver, magnum, and uterus on malondialdehyde (MDA) content, compared with the control (P &lt; 0.05). Compared with the control group, mRNA expressions of glutathione peroxidase 1 (GPX1), peroxidase 4 (GPX4), catalase (CAT), and nuclear factor E2-related factor 2 (Nrf2) in the magnum, liver, and uterus were dramatically rose in the 0.4% PCHM supplementation group (P &lt; 0.05). In summary, dietary supplementation after PCHM increased egg weight and quality in late-phase laying hens.Conclusion: Dietary PCHM increased the antioxidative capacity of late-phase laying hens, which could be associated with increased mRNA expression of antioxidant enzymes and Nrf2. These findings provide potential for using PCHM to increase the production performance in late-phase laying hens.
Biochar amendment alters root morphology of maize plant: Its implications in enhancing nutrient uptake and shoot growth under reduced irrigation regimes
Authors: Wan Heng , Liu Xuezhi , Shi Qimiao , Chen Yiting , Jiang Miao , Zhang Jiarui , Cui Bingjing , Hou Jingxiang , Wei Zhenhua , Hossain Mohammad Anwar , Liu Fulai 
Published: January 2023

IntroductionBiochar amendment provides multiple benefits in enhancing crop productivity and soil nutrient availability. However, whether biochar addition affects root morphology and alters plant nutrient uptake and shoot growth under different irrigation regimes remain largely unknown.MethodsA split-root pot experiment with maize (Zea mays L.) was conducted on clay loam soil mixed with 2% (w/w) of wheat-straw (WSP) and softwood (SWP) biochar. The plants were subjected to full (FI), deficit (DI), and alternate partial root-zone drying (PRD) irrigation from the fourth leaf to the grain-filling stage.Results and discussionThe results showed that, compared to plants grown in unamended soils, plants grown in the biochar-amended soils possessed greater total root length, area, diameter, volume, tips, forks, crossings, and root length density, which were further amplified by PRD. Despite a negative effect on soil available phosphorus (P) pool, WSP addition improved soil available nitrogen (N), potassium (K), and calcium (Ca) pool and cation exchange capacity under reduced irrigation. Even though biochar negatively affected nutrient concentrations in shoots as exemplified by lowered N, P, K (except leaf), and Ca concentration, it dramatically enhanced plant total N, P, K, Ca uptake, and biomass. Principal component analysis (PCA) revealed that the modified root morphology and increased soil available nutrient pools, and consequently, the higher plant total nutrient uptake might have facilitated the enhanced shoot growth and yield of maize plants in biochar-added soils. Biochar amendment further lowered specific leaf area but increased leaf N concentration per area-to-root N concentration per length ratio. All these effects were evident upon WSP amendment. Moreover, PRD outperformed DI in increasing root area-to-leaf area ratio. Overall, these findings suggest that WSP combined with PRD could be a promising strategy to improve the growth and nutrient uptake of maize plants.
Self-leadership as an attribute of service leadership: Its relationship to well-being among university students in Hong Kong
Authors: Shek Daniel T. L. , Zhu Xiaoqin , Dou Diya , Tan Lindan 
Published: January 2023

IntroductionIn the scientific literature, although conceptual models and empirical evidence have shown that leadership attributes are intimately linked to the well-being of followers, there is a lack of studies focusing on leadership in the service economy. According to the Service Leadership Theory, service leadership is a process that satisfies the needs of self, others, and systems (teams, organizations, communities, and societies) in ethical ways that is characterized by leadership competence, character, and care. With specific reference to self-leadership emphasized in service leadership, higher levels of service leadership attributes should promote personal well-being. However, the relationships between “service leadership attributes” and “well-being” in leaders at the intrapersonal level in leadership education among Chinese university students are rarely examined.MethodsIn this study, we collected data from 198 students to understand the linkages between “service leadership attributes” and “well-being” in university students taking a course on service leadership. For tracking changes in students, we collected both pretest and posttest data on validated measures of “service leadership attributes” (i.e., “knowledge,” “attitude,” and “behavior”) and “well-being” (i.e., “positive youth development attributes” and “life satisfaction”).ResultsResults showed that the posttest scores on all three domains of “service leadership attributes” as well as two dimensions of “well-being” encompassing life satisfaction and positive youth development attributes were higher than the respective pretest scores, suggesting that students experienced a shift in a positive direction after taking the course. Cross-lagged analyses showed that pretest service leadership attitude and behavior predicted posttest positive youth development attributes; pretest service leadership behavior predicted posttest life satisfaction. Pretest life satisfaction also predicted posttest service leadership behavior.DiscussionFindings suggest that there is an intimate relationship between “service leadership attributes” and “well-being” in the “pre-work” context among university students.
Ataque de nervios: The impact of sociodemographic, health history, and psychological dimensions on Puerto Rican adults
Authors: Roche-Miranda Marcos I. , Subervi-Vázquez Alisha M. , Martinez Karen G. 
Published: January 2023

IntroductionAtaque de nervios (ADN) is a cultural syndrome prevalent in Puerto Ricans characterized as an episode of intense emotional upset due to overwhelming stress.MethodsThe Ataque de Nervios Questionnaire, developed at the Center for the Study and Treatment for Fear and Anxiety (CETMA), served as the diagnostic tool for this retrospective secondary data analysis. We evaluated three models regarding ADN’s function as a marker of (1) sociodemographic vulnerability, (2) health history risk, and (3) psychological vulnerability. This last model was subdivided to assess the scores of screening tests regarding anxiety (Anxiety Sensitivity Inventory, Beck Anxiety Inventory, and State-Trait Anxiety Inventory), affect (Beck Depression Inventory, Emotional Dysregulation Scale, Positive and Negative Affective Schedule), personality (NEO Five-Factor Inventory), and trauma (considering the responses to the Childhood Trauma Questionnaire and the Life Event Checklist).ResultsOur study sample had a total of 121 Puerto Rican adult patients from CETMA out of which 75% had ADN. We differentiated subjects according to their ADN status with t-tests and Mann-Whitney U tests and evaluated our models using logistic regressions. People with ADN showed more anxiety, depressive symptoms, emotional dysregulation, and negative affect than those without ADN. They also revealed lower positive affect and agreeableness. Highly extraverted but minimally agreeable personalities related to ADN. Living with a partner and being employed were risk factors for ADN. Having higher educational levels showed the strongest effect size: it greatly reduced the odds of an ataque.DiscussionThese characteristics suggest a distinct profile of ADN seen in employed, educated, adult Puerto Ricans living on the Island experiencing anxiety. Our study provides clinical tools to comprehend our patients’ ADN experience, enriching our practice as culturally competent health providers.
Classic psychedelics do not affect T cell and monocyte immune responses
Authors: Rudin Deborah , Areesanan Alexander , Liechti Matthias E. , Gründemann Carsten 
Published: January 2023

IntroductionClassic psychedelics have been shown to exert therapeutic potential for the treatment of various psychiatric disorders, neuropsychiatric diseases, and neuronal damage. Besides their psychopharmacological activity, psychedelics have been reported to modulate immune functions. There has thus far been a sparse exploration of the direct immune-modulating effect of psychedelics on human immune cells in vitro. Since T cells are key mediators of several immune functions, inhibition of their function would increase the risk of infections.MethodsWe investigated the effect of the classic psychedelics lysergic acid diethylamide (LSD), psilocin, N,N-dimethyltryptamine (DMT), and mescaline on the proliferation and stimulated cytokine release of primary human T lymphocytes and on the stimulated NF-κB induction of monocytes.ResultsWe did not observe any relevant direct immune-modulatory effects of the tested classic psychedelics in either cell line.DiscussionWe concluded that LSD, psilocin, DMT, or mescaline did not directly stimulate the proliferation or cytokine secretion of primary human T lymphocytes or stimulate NF-κB induction of monocytes. Our findings support the future safe use of classic psychedelics in assisted psychotherapy in patients with life-threatening diseases where immune suppression and diminished immune function would be detrimental.
Effect of childhood maltreatment on cognitive function and its relationship with personality development and social coping style in major depression disorder patients: A latent class model and network analysis
Authors: Wang Xiao , Li Xinrong , Zhao Juan , Du Xinzhe , Li Junxia , Zhao Wentao , Li Jing , Liu Sha , Xu Yong 
Published: January 2023

Study objectivesThe study aimed to (1) analyze the interrelationships among different types of childhood adversity, diverse personality dimensions, and individual coping style integratively among major depressive disorder (MDD) patients and healthy participants using a network approach; (2) explore the latent class of child maltreatment (CM) and its relationship with cognitive function.MethodsData were collected from the Objective Diagnostic Markers and Personalized Intervention in MDD Patients (ODMPIM) study, including 1,629 Chinese participants. Using the Childhood Trauma Questionnaire to assess CM, the Simplified Coping Style Questionnaire to measure individual coping style, Eysenck Personality Questionnaire Revised-Short Form for personality characters, and a series of neurocognitive tests, including seven tests with 18 subtests for cognitive assessments. We used the “Network Module” in Jeffreys’s Amazing Statistics Program (JASP) and R package for network analysis. A latent class analysis was performed with SAS9.4.ResultsChild maltreatment was more common in MDD patients than in healthy controls, except for emotional abuse. Network analysis showed that emotional abuse, emotional neglect, physical abuse, and physical neglect formed quadrangle connections. Personality dimensions were associated with physical neglect and emotional abuse. All types of CM (excluding sex abuse) showed an association with coping style. Emotional neglect showed the highest centrality measures. Physical neglect had a high level of closeness. To a concerning strength, emotional and physical neglect showed the highest levels. The structure of the networks is variant between groups (M = 0.28, P = 0.04). Latent class analysis (LCA) revealed that three classes provided the best fit statistics. Neglect and abuse classes tended to perform more poorly on the five cognitive domains.ConclusionThis study provided insights on multi-type of CM. Neglect played an important role in different routes through the relation between CM with personality traits and social coping style. However, neglect has often been ignored in previous studies and should receive more public attention.
Prevalence and correlates of sexual harassment in professional service firms
Authors: Hardies Kris 
Published: January 2023

BackgroundDespite their significance, limited research has been conducted on sexual harassment in professional service firms (PSFs).MethodsSurvey data were gathered from 321 Belgian employees (155 women, 166 men) of global accounting and law firms. The prevalence of sexual harassment in PSFs based on traditional sexual harassment items and not-man-enough harassment items was reported. Correlations of respondents' experiences with workplace sexual harassment with perceived acceptance of sexual harassment by one's peers (social norms), personality traits, and demographic and job-related factors were examined.ResultsExperiences of workplace sexual harassment were widespread in the current sample: 88.5% of women and 83.3% of men experienced at least once or twice some form of sexual harassment at work during the past 24 months. The most frequent types of sexual harassment reported are examples of (verbal) forms of gender harassment. Instances of traditional harassment were experienced equally often by men and women, while not-man-enough harassment was much more frequently experienced by women. Severe physical sexual harassment was less frequent. Workplace sexual harassment is positively correlated with perceived acceptance of sexual harassment by one's peers and negatively with job level.ConclusionsResults of the current study align with research that links workplace sexual harassment with workplace culture and suggest that both men and women in PSFs experience enforcement of gender roles. It seems quintessential for firms to create working environments and cultures in which sexual harassment is clearly and unambiguously condemned and sanctioned.
Sex difference in the associations among obesity-related indices with incidence of diabetes mellitus in a large Taiwanese population follow-up study
Authors: Chung Tung-Ling , Liu Yi-Hsueh , Wu Pei-Yu , Huang Jiun-Chi , Chen Szu-Chia 
Published: January 2023

BackgroundObesity is a major risk factor for diabetes mellitus (DM), which is in turn a major risk factor for cardiovascular diseases such as coronary artery disease and stroke. As few studies have investigated sex differences in the association between obesity and incidence of DM, the aim of this longitudinal study was to explore this issue in a large group of Taiwanese participants.MethodsA total of 24,346 participants were enrolled in this study, of whom 8,334 (mean age, 50.6 ± 11.0 years) were male and 16,012 (mean age, 50.5 ± 10.1 years) were female. The following obesity-related indices were studied: body mass index, waist-to-height ratio, waist-to-hip ratio (WHR), body roundness index, conicity index (CI), body adiposity index, abdominal volume index, lipid accumulation product (LAP), and visceral adiposity index (VAI).ResultsThe analysis showed significant associations between all of these indices with incidence of DM (all p &lt; 0.001). In the male participants, the strongest predictors for incidence of DM were LAP (AUC = 0.692), WHtR (AUC = 0.684), and WHR (AUC = 0.683). In the female participants, the strongest predictors were LAP (AUC = 0.744), WHtR (AUC = 0.710) and VAI (AUC = 0.710), followed by BRI (AUC = 0.708).ConclusionStrong associations were found between the studied obesity-related indices and incidence of DM, and sex differences were found. Hence, to better control DM, reducing body weight may be beneficial in addition to lifestyle modifications, diet control, and pharmacological interventions.
Semen parameters and male reproductive potential are not adversely affected after three or more months of recovery from COVID-19 disease
Authors: Stigliani Sara , Massarotti Claudia , Bovis Francesca , Maccarini Elena , Anserini Paola , Scaruffi Paola 
Published: January 2023

BackgroundThe male reproductive system may be a potential target for SARS-CoV-2 since the presence of ACE and TMPRS2 receptors. After a first report of the presence of SARS-CoV-2 in semen of COVID-19 patients, several papers reported that SARS-CoV-2 was not detected in the semen. However, some evidences indicated that COVID-19 disease could impair semen parameters. During the infection, or in a short period after, a reduction in sperm concentration and motility and an increase in DNA fragmentation were observed, even in asymptomatic patients. There is no conclusive data exploring whether this damage changes with time. We investigated whether COVID-19 disease has a negative impact on semen parameters and male reproductive potential after recovery.MethodsIn this longitudinal retrospective study, we enrolled 20 men who had COVID-19 disease. We compared sperm parameters in samples collected before COVID-19 and after infection (8.3 ± 4.8 months). We also evaluated the reproductive potential in pre- and post-COVID-19 infertility treatments of 8 self-controlled couples as well as in 40 cycles after COVID-19 infection of the male partner.ResultsFor most patients, we obtained results of more than one semen analysis before and after COVID-19. After adjusting for age, days of sexual abstinence, frequency of ejaculations and presence of fever, we found no significant difference over time in any semen parameter. The interval between COVID-19 infection and subsequent infertility treatments was 10.7 ± 7.5 months. There were no differences in the embryological and clinical outcomes of infertility treatments performed before and after male infection. One couple obtained a single pregnancy in the post COVID-19 IUI. Normal fertilization (65%), cleavage (99%) and blastocyst development (40%) rates in treatments performed after male infection were within the expected range of competencies. A total of 5 singleton and 1 twin clinical pregnancies were obtained, and 6 healthy children were born. A total of 10 blastocysts have been cryopreserved.ConclusionOur data are reassuring that COVID-19 disease has no negative effect on semen quality and male reproductive potential when semen samples are collected three months or more after infection.
Functional outcomes of tibiotalocalcaneal arthrodesis using a hindfoot arthrodesis nail in treating Charcot's arthropathy deformity
Authors: Bajuri Mohd Yazid , Manas Ammar Muizuddin , Zamri Kamarul Syarazi 
Published: January 2023

BackgroundTibiotalocalcaneal arthrodesis or hindfoot fusion is a salvage surgical option used to treat symptomatic or severe deformity as a result of Charcot’s arthropathy. It is an internal fixation that utilizes nails to stabilize the hindfoot after surgical correction of the deformity. This study intends to measure the change in functional outcomes of patients with Charcot's arthropathy using this technique and the time taken to achieve fusion.MethodThis study presents a series of 40 cases of Charcot's arthropathy where hindfoot fusion was done using a hindfoot arthrodesis nail. A retrospective analysis was done where these patients’ functional scores had been evaluated preoperatively and postoperatively (serially) with the Short-Form Health Survey 36 (SF-36), American Orthopedic Foot and Ankle Society (AOFAS), Foot and Ankle Outcome Score (FAOS), and Foot Function Index (FFI). Along with its complication, the length of time required for the fusion is also reported.ResultsThis study consists of 40 patients (13 men, 27 women; mean age 60.5 years; age range 52–68 years) with a mean follow-up of 64 months (range 24–108 months). The mean time taken for fusion was 5.1 months. All patients showed improvement in functional scoring (SF-36, AOFAS, FFI, and FAOS) postoperatively. We establish that the improvements were gradual over 2 years. Approximately 37.5% of patients had a minor complication and 2.5% had a major complication.ConclusionHindfoot fusion using a hindfoot arthrodesis nail results in improved functional outcome with an acceptable fusion time and acceptable complication rate.Level of evidenceLevel III.
On Approximating the pIC50 Value of COVID-19 Medicines In Silico with Artificial Neural Networks
Authors: Baressi Šegota Sandi , Lorencin Ivan , Kovač Zoran , Car Zlatan 
Published: January 2023

In the case of pandemics such as COVID-19, the rapid development of medicines addressing the symptoms is necessary to alleviate the pressure on the medical system. One of the key steps in medicine evaluation is the determination of pIC50 factor, which is a negative logarithmic expression of the half maximal inhibitory concentration (IC50). Determining this value can be a lengthy and complicated process. A tool allowing for a quick approximation of pIC50 based on the molecular makeup of medicine could be valuable. In this paper, the creation of the artificial intelligence (AI)-based model is performed using a publicly available dataset of molecules and their pIC50 values. The modeling algorithms used are artificial and convolutional neural networks (ANN and CNN). Three approaches are tested—modeling using just molecular properties (MP), encoded SMILES representation of the molecule, and the combination of both input types. Models are evaluated using the coefficient of determination (R2) and mean absolute percentage error (MAPE) in a five-fold cross-validation scheme to assure the validity of the results. The obtained models show that the highest quality regression (R2¯=0.99, σR2¯=0.001; MAPE¯=0.009%, σMAPE¯=0.009), by a large margin, is obtained when using a hybrid neural network trained with both MP and SMILES.
“Na sua escrita eu sou existida”: Lendo a história da Antropologia via Textures of the Ordinary
Authors: Singh Bhrigupati , Rodgers Ana Paula 
Published: January 2023

Neste ensaio, tento sugerir uma forma não teleológica de ler a história da antropologia, situando o livro de Veena Das Textures of the ordinary, de 2020, em relação a suas obras anteriores, começando por Structure and cognition: aspects of Hindu caste and ritual, de 1977. Em vez de um movimento teleológico do estruturalismo ao “pós-estruturalismo” ou a um trabalho “autorreflexivo”, aponto para a continuidade e transfiguração dos conceitos de estrutura e evento nos diferentes livros de Das, como forma de também imaginar movimentos no interior da teoria social mais ampla, sem que cada sucessivo “paradigma” tenha que negar dialeticamente seu antecessor. Pergunto, ainda, o que significa envelhecer ou “amadurecer” no interior de um corpo de trabalho acadêmico, e como podemos considerar que um autor está envelhecendo e rejuvenescendo ao mesmo tempo, se considerarmos que envelhecer no pensamento não é necessariamente apenas uma questão de cronologia ou teleologia.