bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of the collapsible deformation of surrounding rock of loess hydraulic tunnel considering ground stress variation
Authors: She Fangtao , Xu Wanying , Liu Lele , Liu Guoping , Li Lei , Duan Changhui 
Published: July 2023

Abstract
Background
Uneven settlement will occur as a result of the collapsible deformation of the loess strata, and the hydraulic tunnel lining structure will also fail. In this work, laterally confined compression tests were carried out on loess and the double-line method was employed to evaluate the loess collapsibility. The deformation of the surrounding rock of a loess hydraulic tunnel under various ground stresses and its effect on the lining structure were modelled.
Results
Three stages were noted in the collapsible deformation of loess. The critical point between the former two stages corresponds to the pre-consolidation pressure of saturated loess and that between the latter two is taken as the structural yield pressure of unsaturated loess.
Conclusion
From the relationship between the collapsibility coefficient and vertical stress, the deformation of the tunnel under ground seepage primarily originates from two sources, i.e., the collapsible and compressive deformation. The latter source accounts for the deformation of loess adjacent to the lining when the seepage depth is low, while both sources are included when the bottom of the tunnel invert is infiltrated. The collapsible deformation is lower than that of the original stratum due to the stress relaxation during tunnel excavation. The tensile and compressive stresses of tunnel lining increase linearly with the seepage depth, with the maximum appear at a position of 20 m away from the midline of the collapse and non-collapse domains. The results will provide theoretical reference to the design and construction of hydraulic tunnel in collapsible loess stratum.
Federated learning-based detection and control mechanism of in-car navigation safety system
Authors: Gao Jingge , Zhang Shuqiang , Lu Wei 
Published: July 2023

Abstract
The advancement of in-car navigation systems has dramatically improved driving experiences. However, ensuring the safety of these systems remains a critical concern. Federated learning provides a new solution for cooperative learning between non-mutually trusted entities. Through the mode of local training and central aggregation, the local data privacy of each entity is protected while training the global model. To achieve this, a federated learning method for deep learning that preserves privacy is developed by integrating differential privacy with secure multi-party computing. In this scheme, vehicles add perturbations to the local models obtained by local training and secretly share them with multiple central servers. The scheme protects the local information uploaded by users from being stolen and prevents the adversary from malicious inference from globally shared information such as the aggregation model. Additionally, the scheme enables users dropping out and implements a variety of aggregating methods. The aforementioned system may also easily be expanded to decentralized scenarios for real-world applications devoid of a trustworthy center. The experimental findings show that, in order to protect sensitive data obtained from in-car navigation systems during learning, the suggested strategy heavily emphasizes privacy protection. Simultaneously, the high accuracy achieved through the proposed federated learning scheme significantly enhances in-car navigation safety systems' detection and control capabilities. It enables precise and reliable event detection, differentiation of abnormal situations, and reduces false alarms, improving overall safety, user trust, and system performance.
Improving the Performance of the Chaotic Nonlinear System of the Fractional-Order Brushless Direct Current Electric Motor by Using Fractional-Order Sliding Mode Control
Authors: Kaveh Amin , Vahedi Mohammad , Gandomkar Majid 
Published: July 2023

Abstract
Chaos is a dynamic phenomenon that occurs over time in discrete and continuous nonlinear systems for some parameters, and chaotic systems are very sensitive to initial conditions. Controlling a chaotic system means eliminating its chaotic behavior and bringing the system to its origin equilibrium point or another desirable point. Moreover, as most natural systems have fractional dynamics, there is a clear need to study fractional systems. Nowadays, Brushless Direct Current (BLDC) electric motors are widely used as actuator components in many industries. Controlling these nonlinear and multivariable systems is of great importance. Additionally, these systems are often accompanied by parameter uncertainties and external disturbances, which may lead to undesirable and even unstable system behavior. In this research, a three-state-variable chaotic model is presented, and with the help of fractional-order sliding mode control strategy, the performance of the system is improved and controlled compared to conventional sliding mode control. It can be seen that the resistance of the fractional-order BLDC system with fractional-order sliding mode control is significantly higher than that of the conventional BLDC system with conventional sliding mode control against parameter uncertainties and external disturbances. Finally, the controller's performance is evaluated using MATLAB software.
Formation mechanism of mesoporous Cu/CuSe and its application as electrocatalyst for methanol oxidation reaction
Authors: Ullah Nabi , Guziejewski Dariusz , Koszelska Kamila , Małecka Magdalena , Ranoszek-Soliwoda Katarzyna , Grobelny Jarosław , Mirceski Valentin 
Published: July 2023

Abstract
Single step solvothermal method is used to prepare Cu/CuSe as an electrocatalyst for methanol electro-oxidation reaction (MOR). 1,3-butan-diol is selected as a reaction medium, whose viscosity and complex formation with Cu(II) ions, dictate the catalyst morphology. The catalyst has a mesoporous structure, which is composed of nanoballs with a high purity, crystallinity, and uniform morphology. The electrocatalyst is excellent for MOR, as it delivers current density of 37.28 mA/mg at potential of 0.6 V (vs Ag/AgCl) in the electrolyte of 1 M KOH and 0.75 M methanol at a 50 mV/s scan rate under conditions of cyclic voltammetry. The catalyst also shows good stability for 3600 s with negligible charge transfer resistance and high electrochemical active surface area (ECSA) value of 0.100 mF/cm2.
Nicotine exposure and mild cognitive impairment in the elderly：A mixtures approach
Authors: 王 佳辉 , zhang jiuhong , Ren Xiaohu , Liu Peiyi , Fu Ying , Zhi Ying , Zhou Qimei , Xu Benhong , Chen Xiao , Wu Desheng , Deng Huiping , Yang Xifei , Huang Haiyan , Liu Jianjun 
Published: July 2023

Abstract
Background
The relationship between nicotine exposure and cognitive impairment remains controversial. Evidence for combined exposure to its metabolites is also inconclusive. The extensive exposure of metabolites represents the exposure level of nicotine to a certain extent. Therefore, it is essential to explore the comprehensive association between nicotine metabolites and mild cognitive impairment.
Methods
This cross-sectional study measured eight nicotine metabolites in the urine of older adults。 Associations between nicotine metabolites were assessed using logistic regression models. An integrated exposure model was then applied for a comprehensive assessment of metabolites, including Bayesian kernel machine regression (BKMR), weighted quantile sum regression (WQS), and grouped weighted quantile sums (GWQS).
Results
The complete population logistic regression results indicated that CNO was negatively associated with mild cognitive impairment. In contrast, Cot and OHCotGluc showed a trend toward a positive association. Logistic regression results excluding the smoking population showed that OHCotGluc, NNO, and Cot were significantly positively associated with MCI. CNO and OHCotGluc were negatively associated with MCI. In the WQS, the total population had a positive association between combined exposure and mild cognitive impairment (OR: 1.15; 95% CI: 1.04–1.26). Metabolites were grouped for smoking and non-smoking populations based on the BKMR and logistic regression cues. The GWQS results showed an OR of 2.08 (95% CI:1.55,2.83) for the OHCotGluc (43.6%) dominated metabolite group and 0.78 (95% CI:0.613,0.98) for the CNO (55.92%) dominated metabolite group in the non-smoking population. An OR of 2.61 (95% CI:1.42,5.10) for the metabolite group dominated by CotGluc (35.86%) and 0.38 (95% CI:0.19,0.69) for the metabolite group dominated by NNO (47.4%) was found in the smoking population.
Significance
The association of nicotine metabolites with MCI was analyzed using combined exposure and single-factor exposure models. Provides new clues to the cognitive impact of nicotine exposure in older adults.
An extended gradient method for smooth strongly convex functions
Authors: Zhang Xuexue , Liu Sanyang , Zhao Nannan 
Published: July 2023

Abstract
This paper considers an extended gradient method with fixed step size applied to the centralized and decentralized strongly convex and smooth functions. Firstly, the range of step size is derived to guarantee that the function value generated by the extended gradient method converges to the optimal solution at a sublinear rate. Then, we further show that the iterate sequences converge to the optimal solution at a linear rate for the centralized and decentralized problems. Finally, we demonstrate the efficiency of the proposed extended gradient method in numerical experiments.
Factors influencing the need and willingness for presbyopic correction – A cross sectional study from south India
Authors: Khurana Dhruval , N Swathi , Rajalakshmi A.R 
Published: July 2023

Abstract
Background: Presbyopia is an age-related physiological phenomenon in which eye gradually losses its ability to accommodate. It is one of the leading causes of visual impairment worldwide, especially in adults above the age of 40. If uncorrected it can significantly impair patient's quality of life. This study aims to evaluate the factors which affects patient’s need and willingness to accept presbyopic correction.
Methodology: A cross-sectional analytical study was done in semiurban tertiary hospital from Jan 2021 to June 2022. Details of patients aged 40 and above who presented to OPD like whether their chief complaints were related to presbyopia or not, history of spectacle use, systemic diseases, medications and their decision regarding near vision correction were noted. Ophthalmic examination included refraction and ocular biometry. Factors that may have influenced complaints of presbyopia or willingness to accept presbyopic correction were analysed.
Results: Patients with chronic ailments and on chronic medication (p=0.01), higher educational qualification (p=0.031), hypermetropia (p=0.021) and shallower AC depth (p=0.028) were more likely to present with chief complaints attributable to presbyopia. Patients who had chief complains related to presbyopia, those with higher educational qualifications (p = 0.02) and skilled workers were more likely to accept near vision glasses (p = 0.02), while those with lower Hb (p = 0.01) and myopia (p = 0.01) were less likely to accept correction for presbyopia. In patients without chief complaints related to presbyopia and were not willing to accept near vision glasses. Among them, those with higher BMI (p = 0.04) and hypermetropes (p=0.05) were more willing to accept presbyopic correction.
Conclusion: Presbyopia constitutes a significant reason for patients above the age of 40 visiting eye care facility. Multiple socio-economic, systemic and ocular factors influenced both the chief complaints related to presbyopia and willingness to accept presbyopic correction.
Oral health in Behçet's disease and its association with disease severity: cross-sectional and case-control study
Authors: Khalayli Naram , Ataya Jawdat , Darwish Lama Al , Rabah Nour , Rabah Karam , Haidar Ghina , Ataya Jamal , Kudsi Maysoun 
Published: July 2023

Abstract
Background: Behçet's disease is a chronic autoimmune disorder that affects various organs, including oral aphte, genital ulceration, cutaneous manifestation, ocular involvement, and positive pathergy test according to International Study Group for Behçet’s Disease criteria. This study aimed to investigate the oral health condition of patients with Behçet's disease and to assess how it correlates with the patients' gender, clinical symptoms, and severity of the disease.
Methods: A total of 92 participants, including 42 patients with Behçet's disease and 50 healthy controls, were enrolled in this cross-sectional study. The periodontal indices were measured and compared between the two groups. Logistic regression analysis was used to identify potential risk factors for disease severity.
Results: This study assessed the periodontal health of patients with Behçet's disease and found that they had significantly higher plaque, gingival, bleeding, and probing depth scores compared to healthy controls (P<0.05). Logistic regression analysis revealed that plaque accumulation was a significant risk factor for higher severity scores in Behçet's disease. Gender-specific approaches may be necessary in the management and treatment of periodontal disease in Behçet's disease patients.
Conclusions: The findings of this study suggest that patients with Behçet's disease are at increased risk for periodontal disease and its associated symptoms. Specifically, plaque accumulation appears to be a significant risk factor for more severe periodontal health issues in these patients. Therefore, it is important for clinicians to be aware of this increased risk and to develop tailored treatment plans that address both the underlying Behçet's disease and the associated periodontal disease.
Phase Ib and pharmacokinetics study of alpelisib, a PIK3CA inhibitor, and capecitabine in patients with advanced solid tumors
Authors: Lim Ah Reum , Kim Boyeon , Kim Jwa Hoon , Park Kyong Hwa , Kim Yeul Hong , Lee Soohyeon 
Published: July 2023

Abstract
This phase Ib study was performed to determine the safety, the maximal tolerated dose (MTD), and recommended phase II dose (RP2D) of capecitabine with alpleisib in patients with advanced solid tumors. Regardless of PIK3CA mutation, patients were administered orally once daily alpelisib (200mg and 300mg) and twice daily capecitabine (850mg/m2, 1,000mg/m2, 1,250mg/m2, days 1–14) every 3 weeks. Standard “3+3” dose escalation was used to define the MTD. The effect of alpelisib on the PK of capecitabine was assessed. Patients with 6 colorectal cancer (three PIK3CA mutation) and 6 breast cancer (all PIK3CA mutation) were enrolled. The first three patients in dose level 0 (alpelisib 200mg, capecitabine 1,000 mg/m2) had no dose-limiting toxicities (DLTs). In dose level 1 (alpelisib increased to 300 mg), one of six patients had DLT (grade 3 hyperglycemia). At dose level 2 (capecitabine 1,250 mg/m2), no patients had DLTs, establishing it as the MTD/RP2D. The most common AE was grade 1-3 hyperglycemia (75.0%). Antitumor activity was observed in patients with PIK3CA mutant breast cancer (3 partial response and 3 stable disease). Alpelisib was unaffected by capecitabine (Cmax and AUC0-12). This combination is generally tolerated, and shows antitumor activity in patients with PIK3CA mutant advanced cancers.
Comparison of electronic nose and conventional cow-side diagnostic tools for detection of ketosis in early lactation dairy cows
Authors: Schelkopf C. S. , Apley M. D. , Lubbers B. V. 
Published: July 2023

Ketosis is a metabolic disease observed in early lactation, high-producing dairy cows. The disease state is characterized by a negative energy balance with increases in serum, milk and urine ketone bodies (acetoacetate [AcAc], acetone and beta-hy­droxybutyrate [BHB]). Rapid diagnosis of ketosis is imperative for implementing proper treatment protocols and managing economic losses associated with reduced milk production and reproductive performance, increased culling rates and treat­ment costs.
Conventional cow-side diagnostic tools providing rapid results for ketosis detection have improved disease identification; however, these tools still require farm personnel to identify potential ketosis cases prior to their use. The implementation of a hands-off, continuous monitoring system within a produc­tion setting would streamline the diagnostic process leading to real-time health management without the need for a subjective clinical assessment.
Advancements in the non-invasive detection of volatile com­pounds holds potential in the veterinary field for disease diag­nosis. Electronic nose (Enose) technology utilizes volatile com­pounds from patient samples, such as breath, urine or milk to classify disease. Incorporating Enose technology into a contin­uous monitoring system could provide a modernized approach to cattle health management.
The objective of this study was to explore the capabilities of the Enose for ketosis detection in early lactation dairy cattle and compare its performance to diagnostic tools currently used in the dairy industry.
Synthesis and characterization of p-carboxy phenyl amino maleimide-g-cellulose acetate/ZrO2 nanocomposite membrane for water desalination
Authors: Abdel-Naby Abir , Alabdullatif Bushra A. , Aldulaijan Sarah , Alqarni Yanallah 
Published: July 2023

Abstract

The reaction of p-carboxy phenyl amino maleimide (CHM) with cellulose acetate (CA) led to the formation of a modified cellulose acetate polymer (MCA), which was characterized by UV/Vis, 1H NMR, and 13C NMR. The active sites of the reaction were the –NH group of (CHM) and the OAc of CA. CA was grafted with (CHM) to build branches on its main chains, using benzoyl peroxide as an initiator. The results of 1H NMR and 13C NMR revealed the presence of (CHM) moieties inside the polymeric matrix. The (CA-g-CHM) ZrO2 was fabricated into a membrane, using a phase inversion technique. The effect of ZrO2 content on the water flux was discussed. The SEM/EDS was also used to characterize the membrane contents and morphology. The morphology of the membrane showed the grafted parts and the EDS confirmed the presence of nitrogen atoms in the polymeric matrix. The thermogravimetry (TGA) results showed that the membrane exhibited high thermal stability which would adjust the membrane for the desalination process. The desalination test indicated the removal of NaCl salt by the membrane, as shown by the EDS and 1H NMR spectroscopy results. The membrane exhibited good antibacterial and antifungal properties.
Current Update of Research on Exosomes in Cancer
Authors: Tendulkar Reshma , Tendulkar Mugdha 
Published: July 2023

Abstract:
Exosomes are vesicles secreted by the plasma membrane of the cells
delimited by a lipid bilayer membrane into the extracellular space of the cell. Their
release is associated with the disposal mechanism to remove unwanted materials from
the cells. Exosomes released from primary tumour sites migrate to other parts of the
body to create a metastatic environment for spreading the tumour cells. We have
reviewed that exosomes interfere with the tumour progression by (i) promoting
angiogenesis, (ii) initiating metastasis, (iii) regulating tumour microenvironment (TME)
and inflammation, (iv) modifying energy metabolism, and (v) transferring mutations. We
have found that EVs play an important role in inducing tumour drug resistance against
anticancer drugs. This review discusses the potential of exosomes to generate a
significant therapeutic effect along with improved diagnosis, prognosis, insights on the
various research conducted and their significant findings of our interest.
Determinants of Inadequate Health Literacy Among Faculty of Medical Technical Sciences Students in Albania: Cross-Sectional Survey
Authors: Rustami Etleva , Toçi Dorina , Poshi Klodiana , Peka Elida , Pano Irida , Pula Alma 
Published: July 2023

Background
Health literacy (HL) refers to people’s ability to find, understand, and use health information in order to make appropriate health decisions. Health literacy among students is important so that tomorrow’s health professionals can deliver high-quality health care and enhance patient education and communication.

Objective
In this context, the aim of this study was to assess the HL level of Faculty of Medical Technical Sciences (FMTS) students in order to shed light on this underresearched topic in Albanian settings.

Methods
A cross-sectional study involving 193 FMTS students of various study branches (nursing, midwifery, physiotherapy, and laboratory technician) was carried out during June 22-29, 2022, on the premises of the FMTS Faculty in Tirana, Albania. The international European Health Literacy Survey Questionnaire (HLS-EU-Q) standardized questionnaire, validated in Albanian, was used to collect information about FMTS students’ general HL through a face-to-face interview. Basic sociodemographic information was collected as well. Binary logistic regression was used to assess the factors associated with inadequate, problematic, or limited HL.

Results
The mean level of general HL was 37.2 (on a scale from 0 [minimum HL] to 50 [maximal HL]). About one-quarter of FMTS students had inadequate (9/193, 4.7%) or problematic (38/193, 19.7%) HL, 51.3% (99/193) had sufficient HL, and 24.4% (47/193) had excellent HL. The prevalence of limited HL (inadequate and problematic HL) was higher among male than female students (6/12, 50% vs 41/181, 22.6%, respectively) and those with lower social and economic status. Upon adjusting for confounding effects, the only factor significantly increasing the likelihood of limited HL was male gender (odds ratio 8.13, 95% CI 1.68-39.39). Findings suggested that low social and economic status also increased the likelihood of limited HL, but such associations did not reach statistical significance.

Conclusions
To our knowledge, this is the first study exploring the level of HL and its associated factors among FMTS students in Albania. The prevalence of limited HL was relatively high among FMTS students. There is a need for targeted interventions to increase the HL of nursing and midwifery students, such as the inclusion of HL subjects in the nursing curriculum.
ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI IMPLEMENTASI STANDAR AKUNTANSI KEUANGAN ENTITAS MIKRO KECIL DAN MENENGAH (SAK EMKM) DI KOTA JAMBI (STUDI KASUS PADA UMKM BATIK DI SEBERANG KOTA JAMBI)
Authors: Sholihin M , Mukhzarudfa Mukhzarudfa , Tiswiyanti Wiwik 
Published: July 2023

Penelitian ini dilakukan untuk menguji pengaruh sosialisasi, jenjang pendidikan, ukuran usaha, umur usaha dan pemahaman teknologi informasi terhadap implementasi SAK EMKM, baik secara parsial maupun simultan. Data yang digunakan dalam penelitian ini adalah data sekunder yang diperoleh dari Dinas Koperasi dan UKM Kota Jambi, literatur, dan jurnal penelitian, sedangkan data primer diperoleh langsung dari UMKM Batik Seberang Kota Jambi. Populasi penelitian ini adalah UMKM Batik Seberang Kota Jambi, Pemilihan sampel menggunakan teknik purposive sampling dengan berbagai kriteria jumlah sampel sebanyak 41 UMKM. Penelitian ini merupakan penelitian casual-comparative research. Teknik analisis yang digunakan adalah regresi linier berganda dan uji hipotesis menggunakan t-statistik untuk menguji koefisien regresi parsial serta f-statistik untuk menguji pengaruh secara simultan dengan tingkat kepercayaan 5%. Selain itu semua variabel telah diuji dengan uji asumsi klasik. Hasil penelitian ini menunjukkan bahwa sosialisasi dan ukuran usaha berpengaruh terhadap implementansi SAK EMKM, namun jenjang pendidikan, umur usaha dan pemahaman teknologi informasi tidak berpengaruh terhadap implementansi SAK EMKM.