bluuebunny/crossref_metadata_2025_split huggingface dataset:
High-Quality Sleep Mitigates ABCA7-Related Generalization Deficits in Healthy Older African Americans
Authors: Sinha Neha , Fausto Bernadette A. , Mander Bryce , Gluck Mark A. 
Published: May 2023

Background: Both sleep deficiencies and Alzheimer’s disease (AD) disproportionately affect older African Americans. Genetic susceptibility to AD further compounds risk for cognitive decline in this population. Aside from APOE ɛ4, ABCA7 rs115550680 is the strongest genetic locus associated with late-onset AD in African Americans. While sleep and ABCA7 rs115550680 independently influence late-life cognitive outcomes, we know too little about the interplay between these two factors on cognitive function. Objective: We investigated the interaction between sleep and ABCA7 rs115550680 on hippocampal-dependent cognitive function in older African Americans. Methods: One-hundred fourteen cognitively healthy older African Americans were genotyped for ABCA7 risk ( n = 57 carriers of risk “G” allele; n = 57 non-carriers), responded to lifestyle questionnaires, and completed a cognitive battery. Sleep was assessed via a self-reported rating of sleep quality (poor, average, good). Covariates included age and years of education. Results: Using ANCOVA, we found that carriers of the risk genotype who reported poor or average sleep quality demonstrated significantly poorer generalization of prior learning—a cognitive marker of AD—compared to their non-risk counterparts. Conversely, there was no genotype-related difference in generalization performance in individuals who reported good sleep quality. Conclusion: These results indicate that sleep quality may be neuroprotective against genetic risk for AD. Future studies employing more rigorous methodology should investigate the mechanistic role of sleep neurophysiology in the pathogenesis and progression of AD associated with ABCA7. There is also need for the continued development of non-invasive sleep interventions tailored to racial groups with specific AD genetic risk profiles.
Efficacy of Therapy vs Surveillance in Patients with Resected Early-Stage Intermediate to High-Risk Renal Cell Carcinoma
Authors: Major C. Kendall , Rodriguez Carlos I. , Haas Naomi B. 
Published: May 2023

BACKGROUND: The historical standard of care for locally advanced renal cell carcinoma (RCC) is nephrectomy + active surveillance. Despite a high recurrence rate ( 40%), adjuvant therapy was previously not included in the standard of care. This review of adjuvant pharmacotherapy reflects conflicting results from multiple trials. OBJECTIVE: The objective of this review is to summarize the efficacy of therapy vs surveillance in resected early-stage intermediate to high-risk renal cell carcinoma. METHODS: We performed a systematic literature search using PubMed, EMBASE, and SCOPUS. Keywords such as “renal cell carcinoma”, “adjuvant therapy” and “nephrectomy” were used. In the literature search, 2,711 studies were identified and screened. RESULTS: We included a total of 21 publications. The most common histology seen in trials was clear cell carcinoma. A variety of interventions were reviewed including immunotherapy, medroxyprogesterone acetate, interferon alfa, and tyrosine kinase inhibitors. Most trials did not demonstrate a benefit in relapse-free survival (RPS) or overall survival (OS). Pembrolizumab demonstrated a significant difference in disease recurrence in the KEYNOTE-564 trial although median data was not reached. Blinded independent reviewers identified a benefit in disease-free survival (DFS) with Sunitinib in the S-TRAC trial. CONCLUSION: There was not a clear benefit in using adjuvant therapy broadly for resected locoregional RCC; however, further investigation should be done in the highest-risk group to elucidate potential benefit.
Indonesian Brown rice improves obesity parameters and dysbiosis of gut microbiota
Authors: Sulistyowati Etik , Handayani Dian , Soeharto Setyawati , Huang Xu F. , Rudijanto Ahmad 
Published: May 2023

BACKGROUND: Brown rice contains nutrients that significantly reduce the incidence of obesity. This study aimed to investigate the effect of brown rice as a functional food on the reduction of obesity incidence through the pathways of gut microbiota dysbiosis. METHODS: In this study, we used white rats ( Rattus norvegicus albus), which were divided into five groups, i.e., Normal, High fructose feed diet (HFFD), HFFD + Brown rice (BR) I, HFFD + BR II, HFFD + BR III. The parameters were SCFA concentration, FFAR3 expression, and Firmicutes– Bacteroidetes ratio. RESULTS: The rats fed HFFD + BR III diet with a high intake of brown rice resulted in a greater reduction in abdominal circumference. The group of rats fed the HFFD had a higher BFI than the other rats. The brown rice intervention reduced the Lee index, a higher concentration of short-chain fatty acid (SCFA), and led to a higher reduction in Firmicutes– Bacteroidetes ratio. The brown rice intervention also increased the FFAR3 expression in the rat ileal L cells. CONCLUSIONS: Brown rice has significant benefits for reducing obesity, as evidenced by the improvement in the abdominal circumference, Lee index, and BFI through the improvement of intestinal dysbiosis and increase in SCFA concentration and FFAR3 expression.
POLA KOMUNIKASI KELUARGA DALAM MEMBENTUK KEPRIBADIAN ISLAMI ANAK DI KAMPUNG SINAR HARAPAN RAJABASA JAYA KOTA BANDAR LAMPUNG
Authors: Nasor M. , Wahyu M. , Rifa’i Rendra Nasrul , Utama Esen Pramudya , Puspita Sari Nina Ayu Ayu 
Published: May 2023

In Islam, children are very important. Islam does not treat children by wasting them. In essence, children are a mandate from Allah SWT. While parents are educators for their children, they have a great responsibility for their children's growth and development. As for the education carried out by parents to their children, it is solely to create people who are faithful, pious and knowledgeable who are able to develop themselves into obedient servants of Allah. This obedient servant of Allah can be seen from his personality, Islamic personality is behavior that is in accordance with Islamic values, both in the form of worship, especially prayer and fasting, as well as good morals, especially discipline, responsibility, and respect. Thus, parents as educators are obliged to form Islamic personalities in children from an early age, especially when children are 7-12 years old. In general, children at this age really like to play and often meet with other important activities. In addition, this age is also known as the ripe period for learning. So that parents can use it to instill religious behavior in children.
From this background, the author examines what are the patterns of family communication in shaping the personality of Islamic children in Sinar Harapan Village, Rajabasa Jaya Village, Bandar Lampung City? and what are the effects of family communication on the child's Islamic personality?. This study aims to explain the communication pattern of the child's family in shaping the Islamic personality and explain the effect of family communication on the child's Islamic personality. This research is a type of research that collects data from the field, which is descriptive qualitative. In taking the sample, the researcher used a purposive sampling technique, namely taking samples with certain criteria. Data collection tools used in this study were interviews, observation and documentation.
As for the findings in this study, families in Sinar Harapan Village use a communication pattern in the form of dyadic interpersonal communication which in the communication process uses a two-way communication model, and gets direct responses that are positive or negative. dyadic interpersonal relationships are carried out by means of hiwar, stories, examples, habituation, tarhib, advice and punishment. The effects of family communication on children include cognitive, affective and behavioral effects.
Analisis Vegetasi Gulma pada Lahan Tanaman Jagung di Kecamatan Insana Tengah Kabupaten Timor Tengah Utara
Authors: Kamaluddin Kamaluddin , Hano’e Emanuel M. Y. , Pardosi Lukas 
Published: May 2023

Penelitian ini dilaksanakan untuk mengetahui jenis gulma dan indeks keanekaragaman gulma pada tanaman jagung di Kecamatan Insana Tengah Kabupaten Timor Tengah Utara. Penelitian dilakukan dengan menggunakan metode kuadrat sebanyak 10 plot dengan ukuran 1x1 m2. Hasil penelitian menunjukkan bahwa ditemukan 11 Famili dengan 614 Individu pada lokasi penelitian. Spesies paling banyak ditemukan yaitu famili Asteraceaae sebanyak 403 individu, Famili Euphorbiaceae sebanyak 67 individu, Famili Poaceae sebanyak 65 Individu dan Spesies paling sedikit ditemukan yaitu Famili Fabaceae dimana ditemukan 2 individu. Spesies gulma yang memiliki nilai SDR tertinggi dan terendah yaitu Sinedrella nodiflora L. dengan nilai SDR: 38,89%, dan Desmodium triflorium L. DC merupakan gulma yang memiliki nilai SDR paling rendah yaitu SDR: 1,66%. Nilai indeks keanekaragaman jenis gulma yaitu H’=1,461 dengan kategori sedang.
INSECTICIDAL EFFECT OF NEEM (Azadirachta indica a.juss) LEAF AQUEOUS EXTRACT ON FLEA BEETLE (Podagrica spp) ON ROSELLE (Hibiscus sabdariffa L) IN KEBBI STATE-NIGERIA.
Authors: KHADIJA U.Z. , RAHMA I. , JEGA I.Y. , FAKAI A.U. , YUSUF A.U. , MOHAMMED I.U. 
Published: May 2023

The study evaluates the efficacy of the neem leaf aqueous extract NLAE at different graded levels on flea beetle (Podagrica spp) infecting roselle (Hibiscus sabdariffa L.) varieties in rainy season in 2020 at Aliero and Jega, Kebbi State, Nigeria. The treatment consisted of three varieties of Roselle Green (V1), Red (V2), and deep red (V3) and three graded level of NLAE (C1-1000mg/mL, C2-500mg/mL, C3-333mg/mL) and control (C0-0mg/mL). The experiment was laid out in randomized complete block design (RCBD) in a split plot arrangement and replicated three times. Different graded extracts were sprayed as Roselle flowering reaches 50%. The spraying procedure was repeated at 0 day before spray (DBS), 1, 2, 3, 5 and 7 days after spraying (DAS) with (NLAE). Data were collected on Flea count, number of fresh and dried calyx, fresh and dried leaf yields per hectare (kg/ha). The results revealed that Podagrica spp were identified as a major pest complex affecting Roselle production. Furthermore, results also revealed the efficiency of the Neem leaf aqueous at different grade levels on pest affecting Roselle, while untreated control recorded the highest number of Podagrica spp with significant difference among the treatment that eventually have great effect of the yield of Roselle.
ECONOMICS OF SMALL-SCALE CASSAVA PROCESSING IN ADAVI LOCAL GOVERNMENT AREA OF KOGI STATE
Authors: AKUBO D , USMAN F.R. , ABUBAKAR U.A. , EGBUNU M.M. , IYAJI J. 
Published: May 2023

This study examined economics of small-scale cassava processing in Adavi Local Government Area of Kogi State. Specific objectives were to: describe the socioeconomic characteristics of cassava processors, assess the profitability of small-scale cassava processing and determine factors affecting the income of cassava processors. 120 respondents were selected from the list of cassava processors from Agricultural Development Project (ADP) and Adavi Local Government. Primary data used were collected using a structured questionnaire. Data were analysed with Descriptive statistics and Linear Regression. Results showed that respondents had a mean age of 37 years, 66% of the respondents were females, 45% of the respondents were married. 38.33% of the respondents acquired secondary education. The mean household size was 7 persons. The mean years of processing experience was 8 years. 61.67% of processors were members of cooperative societies. 72.50% of the respondents used household members as employees. Gross Margin of N 33,443.3, benefit-cost ratio of 2.72 and the operating cost ratio of 0.367 showed that cassava processing was viable and profitable. Independent variables included in the model were all statistically significant at 5% alpha level. Cassava processing in the study area is a profitable venture. Favourable pricing policies that will help to lessen the cost of processing should be put in place, this will in turn help to lessen processors’ selling prices and thus enable them withstand market competition thereby continue to be in business.
PENCIPTAAN KARYA TARI â€œANAKKU BERMAINâ€
Authors: Diana Silvi Fitriah 
Published: May 2023

The reason for this research was the lack of development of creativity and the poor learningspirit among school children. This is due to the fact that educators still tend to use conventionalteaching methods in the teaching and learning process. The question addressed in the research iswhether the creativity and learning spirit of children in the first and second years of the An-NurKindergarten in the District of Jember, in which a play-based learning model is implemented,will develop to an optimal level. The goal of this research is to discover the results of implementinga play-based learning model on the creativity and learning spirit of children at school. Thebenefits of the research are: (1) for the children, to increase their learning spirit and develop theircreativity; (2) for the educator, to implement play-based learning in the teaching and learningprocess in the classroom; and (3) for the school, to create an innovation in the learning processwhich is suitable for the world of children while at the same time remaining relevant to thenuance of learning that is required according to the curriculum. The nature of the research is aclassroom action study which includes planning, implementation, and evaluation. The researchdata includes the data of the activities and the results of the development of the childrenâ€™s creativitywith the implementation of a play-based learning model. The data was obtained throughÂ demonstrations, observation, discussions, and field notes. The results of the research show thatthere is an increase in learning, evident both in the activities of the teachers in the teaching andlearning process and also in the results of the observation and demonstrations. This increase canbe seen in every study inside the classroom which uses personal notes, firstly with adequate development(c) and secondly with very good development (SB). The conclusions of the research arethat using a play-based learning model can increase the creativity and learning spirit of childrenin the An-Nur Kindergarten in the Sub-District of Kaliwates in the District of Jember.Keywords: Play-Based Learning Model, Creativity, Childrenâ€™s Learning SpiritÂ
TARI KETHEK OGLENG SEBAGAI EKSPRESI SENI KOMUNITAS CONDRO WANORO DESA TOKAWI KECAMATAN NAWANGAN KABUPATEN PACITAN
Authors: Peni Catur Mustika , Pramutomo RM. 
Published: May 2023

AbstrakÂ Ekspresi merupakanhasil dan bentuk manifistasi dari emosi ekspresi, juga merupakan pengungkapan dalam suatu proses mengutarakan maksut. Tari Kethek Ogleng merupakan sebuah tarian yang menjadi jembatan bagi para pelaku seni yang ada di Komunitas Condro Wanoro. Tari kethek ogleng adalah tari yang diciptakan guna untuk memberikan nuansa baru di sebuah desa. Tarian ini bisa disajikan secara kelompok, individu dan pasangan.. Permasalahan dalam penelitian ini adalah bagaimanabentuk tari Kethek Ogleng Desa Tokawi Kecamatan Nawangan dan mengapa ekspresi seni komunitas Condro Wanoro terbentuk melalui tari Kethek Ogleng. Konsep yang di gunakan untuk menganalisis bentuk tari Kethek Ogleng Desa Tokawi ini ialah Sumandyo Hadi. yang meliputi urutan sajian, Penari, gerak, pola lantai, karawitan, atau music tari, rias dan busana, tempat dan waktu pertunjukan. Untuk mengupas ekspresi yang terbentuk melalui tari Kethek Ogleng mengunakan teori dari Setephanie Ross. Metode yang digunakan dalam penelitian ini mengandalkan data kualitatif dalam hal pengumpulan data dan yang menghasilkan data deskriptif. Hasil penelitian ini menunjukkan bahwa ekspresi yang terbentuk melalui tari Kethek Ogleng itu ada beberapa hal yang mendasari sebuah ekspresi itu sendiri. Ada beberapa model orientasi ekspresi yang terbentuk dalam sebuah komunitas melalui tari Kethek Ogleng. Orientasi itu diantaranya adalah Orientasi Keagamaan atau religi, Orientasi Solidaritas, orientasi komunikasi, orientasi kekeluargaandan Orientasi Integratif. Simpulan dari penelitianini yaitu tari Kethek Ogleng merupakan tari yang digunakan sebagai penyalur bagi para pelaku seni yang ada di Komunitas Condro Wanoro.Kata kunci : Tari Kethek Ogleng, Bentuk Tari, Ekspresi Komunitas.Â AbstractÂ The Expression is a result of the manifestation from emotion. It was also the process to respond the way emotion proposed. This article will strives a Kethek Ogleng which is belong to the bridge among dance participants of Condro Wanoro Community. This dance form was created to present a new nuance from the country side. Generally it was also presented by individual,Â Â duet or in a group. This article will examine the Kethek Ogleng dance form in Tokawi Village, Kecamatan Nawangan and why they have Condro Wanoro Community which was supporting thir dance form. Choreograplically this article will use. Y. Sumandiyo Hadi concepts of dance choreographyâ€™s as recreasional form. Another side it is also examine the many aspects of Choreog- raphy. There is another concept of arts as community expression from Stephanie Ross. From this concept this article will expose several orientation of community like, religion orientation, soli- darity orientation, communication orientation, family orientation, and integrative orientation. The perspective will use in this article called ethnochoreological perspective and practically using dance ethnography method.Keywords: Tari Kethek Ogleng, Dance Form, Expression of Community.
NDALEM PADMASUSASTRO SEBAGAI RUANG PERTUNJUKAN ALAM NATURAL (Ndalem Padmasusastro as a natural performing stage)
Authors: Efrida Efrida 
Published: May 2023

Space (is) esensial element in a(n show. Space become the place of to artistic expression blaze outburst explosion of feeling. Natural spaceÂ (of)Â natural with strong column value and character have potency to become a show space. This matter (is) determined by sensitivity (of) choreographer to catch strength (of] potency and space a space so that can mengekplorasinya maximally to ajang afn show. Ndalem Padmasusastro with joglo house building and wide [of] background representing air-gap which consist of some space where each space have different space value and characterIts existence as natural show space [of) natural at the same time as public space make Nda!em Padmasusastro as space capable to accommodate incoming public importance and give freedom (at] public to determine (by] xself focus their attention and express artistic (soul! head] (of) them to show which look on is theÂ Keyword: Ndalem Padmasusastra, natural show space (of) natural, space.
PERANCANGAN BACKDROP UNTUK PERNIKAHAN DENGAN TEKNIK MAKRAME
Authors: Sabilla Mukhlisa , Widyastuti Theresia 
Published: May 2023

ABSTRAKMukhlisa Sabilla. C0915029. 2019. Perancangan Backdropuntuk Pernikahan menggunakan Teknik Makrame.Tugas Akhir: Program Studi Kriya Tekstil Fakultas Seni Rupa dan Desain Universitas Sebelas Maret.“Perancanganbackdrop untuk pernikahan menggunakan teknik makrame” bertujuanmengeksplorasi simpul-simpul makame yang dibuat menjadi dekorasi pernikahan. Hasil perancangan menjadi produk yang inovatif dan memiliki diferensiasi produk. Realisasi produk dapat menambah kekayaan visual makrame yang berfungsi sebagai dekorasi pernikahan.Hasil perancangan adalah backdrop untuk pernikahan dibuat dengan teknik makrame dengan mengambil ide dari bentuk flora yaitu daun sirih gading dan bunga lotus, bentuk fauna yaitu kupu-kupu, motif kawung, wajikan, ukel/besusulan, tumpal/sorot dan jumbai. Backdrop terdiri dari 3 bagian, bagian utama berada di tengah, bagian pelengkap ada di sisi kiri dan kanan. Pemasangan backdrop pada kerangka kayu yang terinspirasi dari bentuk dasar rumah. Backdrop dengan teknik makrame menawarkan nuansa yang berbeda dari segi estetik dan wujud visual. Kata kunci:backdrop pernikahan, makrame ABSTRACTMukhlisa Sabilla. C0915029. 2019. Backdrop Design for Wedding using the Macrame Technique. Final Project: Textile Craft Study Program, Faculty of Arts and Design, Sebelas Maret University."Designing backdrop for wedding using the macrame technique" aims to explore the makame knots made into wedding decorations. The design results into an innovative product and has product differentiation. The realization of the product can add to the visual wealth of macrames that function as wedding decorations.The result of the design is a backdrop for wedding made with macrame techniques by taking the idea of the shape of flora sirih gading leaves and lotus flowers, the form of fauna butterflies, kawung motifs, wjikan, ukel/besusulan, tumpal/sorot and tassels. Backdrop consists of 3 parts, the main part is in the middle, the complement is on the left and right. Laying the backdrop on a wooden frame inspired by the basic shape of the house. Backdrop with macrame technique offers different nuances in terms of aesthetics and visual appearance. Keywords: wedding backdrop, macrame
Perlindungan Hukum Bagi Pencari Suaka (Asylum Seeker) Di Wilayah Indonesia
Authors: Pramesti Ivana Putri Kinasih  , Eko Wahyudi  , Miko Aditiya Suharto  
Published: May 2023

Tujuan utama penelitian ini adalah untuk mengetahui perbedaan antara perlindungan hukum yang diberikan kepada pengungsi dan pencari suaka di wilayah Indonesia menurut hukum internasional dan hukum nasional Indonesia, serta dampak hukum yang akan dihadapi pencari suaka di sana menurut hukum pengungsi internasional. Penelitian ini menggunakan pendekatan perundang-undangan dan pendekatan konseptual dalam metodologi penelitian yuridis normatifnya. Sumber hukum yang digunakan dalam penelitian ini adalah sumber hukum primer, seperti undang-undang dan konvensi internasional, dan sumber hukum sekunder, seperti buku dan jurnal ilmiah. Dalam rangka pemenuhan hak asasi manusia, termasuk pemberian perlindungan hukum dan perlakuan terhadap pengungsi dan pencari suaka asing, temuan studi dikaitkan dengan hukum dan peraturan Indonesia serta norma global.
Kata kunci : Pencari Suaka, Pengungsi, Perlindungan Hukum, UNHCR.
Shakespeare, Montaigne and Moral Luck
Authors: McNair Maria Devlin 
Published: May 2023

The term ‘moral luck’ refers to the ‘problematic or paradoxical fact that factors decisive for the moral standing of an agent are factors subject to luck’ (Walker). This chapter argues that Montaigne and Shakespeare disagree not only on the reality of moral luck but also on the dangers it might pose. Montaigne rejects moral luck insofar as he adopts a Stoic ethos, which identifies the autonomous will as the ground of moral judgment and the basis of excellence – excellence that could be compromised if moral luck were real. The Christian ethos dramatized by Shakespeare insists that the will is not autonomous, and locates the highest value, not in one’s own excellence, but in relationships with others. When those relationships are compromised by sin, full reconciliation often requires moral luck. For Montaigne, the greatest threat would be to suffer bad moral luck; for Shakespeare, it would be to miss out on good moral luck.