bluuebunny/crossref_metadata_2025_split huggingface dataset:
Determinants of post-COVID-19 symptoms among adults aged 55 or above with chronic conditions in primary care: data from a prospective cohort in Hong Kong
Authors: Zhang Dexing , Chung Vincent Chi-Ho , Chan Dicken Cheong-Chun , Xu Zijun , Zhou Weiju , Tam King Wa , Lee Rym Chung-Man , Sit Regina Wing-Shan , Mercer Stewart W. , Wong Samuel Yeung-Shan 
Published: May 2023

BackgroundPrimary care patients, especially those with an older age, are one of the most vulnerable populations for post-COVID-19 symptoms. Identifying predictors of post-COVID symptoms can help identify high-risk individuals for preventive care.MethodsOut of 977 primary care patients aged 55 years or above with comorbid physical and psychosocial conditions in a prospective cohort in Hong Kong, 207 patients infected in the previous 5–24 weeks were included. The three most common post-COVID-19 symptoms (breathlessness, fatigue, cognitive difficulty), which lasted beyond the 4-week acute infection period, were assessed using items from the COVID-19 Yorkshire Rehabilitation Scale (C19-YRS), together with other self-reported symptoms. Multivariable analyses were conducted to identify predictors of post-acute and long COVID-19 symptoms (5–24 weeks after infection).ResultsThe 207 participants had a mean age of 70.8 ± 5.7 years, 76.3% were female, and 78.7% had ≥2 chronic conditions. In total, 81.2% reported at least one post-COVID symptom (mean: 1.9 ± 1.3); 60.9, 56.5 and 30.0% reported fatigue, cognitive difficulty, and breathlessness respectively; 46.1% reported at least one other new symptom (such as other respiratory-related symptoms (14.0%), insomnia or poor sleep quality (14.0%), and ear/nose/throat symptoms (e.g., sore throat) (10.1%), etc.). Depression predicted post-COVID-19 fatigue. The female sex predicted cognitive difficulty. Receiving fewer vaccine doses (2 doses vs. 3 doses) was associated with breathlessness. Anxiety predicted a higher overall symptom severity level of the three common symptoms.ConclusionDepression, the female sex, and fewer vaccine doses predicted post-COVID symptoms. Promoting vaccination and providing intervention to those at high-risk for post-COVID symptoms are warranted.
First year nursing students’ reflections about developing their verbal nursing skills during their nursing education in China: a qualitative study
Authors: Zhu Xiaoling , Rask Mikael , Xu Hongbo 
Published: May 2023

ObjectiveThe aim of the study is to explore the expectations of a group of first-year nursing students in China about developing their verbal and social interactional skills during their nursing education.BackgroundNursing students’ communication skills were not fully developed in China. Students have many challenges to face regarding developing their nursing skills, especially interaction skills, when they start their education.DesignA qualitative design was used in this research.MethodTwelve second-semester undergraduate nursing students were interviewed on the basis of purposive sampling, and qualitative content analysis was employed.ResultsThe main theme was ‘facilitating a caring nurse–patient relationship’ and ‘using a knowledge base for performing nursing care’. The first theme comprises two sub-themes, ‘caring approach’ and ‘helping and involving the patient in care’, with three and two categories, respectively. The second theme comprises the two sub-themes, ‘knowledge needed to be able to understand the patient’ and ‘health and treatment information’, with three and two categories, respectively.ConclusionA synthesis of both knowledge and practice is needed to improve the nursing students’ interaction and professional skills during their nursing education.
Factors associated with caregiver compliance to an HIV disclosure intervention and its effect on HIV and mental health outcomes among children living with HIV: post-hoc instrumental variable-based analysis of a cluster randomized trial in Eldoret, Kenya
Authors: Magill Elizabeth B. , Nyandiko Winstone , Baum Aaron , Aluoch Josephine , Chory Ashley , Ashimoshi Celestine , Lidweye Janet , Njoroge Tabitha , Sang Festus , Nyagaya Jack , Scanlon Michael , Hogan Joseph , Vreeman Rachel 
Published: May 2023

BackgroundThe HADITHI study is a cluster-randomized trial of children living with HIV and their caregivers in Kenya that aimed to increase rates of caregiver disclosure of their child's HIV status, encourage earlier status disclosure, and improve pediatric mental health and HIV outcomes. This analysis identified characteristics predicting caregiver non-responsiveness and compared outcomes among children based on disclosure status.MethodsA penalized logistic regression model with lasso regularization identified the most important predictors of disclosure. The two-stage least squares instrumental variable approach was used to assess outcomes accounting for non-compliance to disclosure.ResultsCaregiver non-isolation and shorter time on antiretroviral therapy were predictive of HIV status disclosure. There were no statistically significant differences found in CD4 percentage, depression status, or mental and emotional status based on disclosure status up to 24 months-post intervention.ConclusionThese findings have implications for specialists seeking to tailor disclosure interventions to improve caregiver-child dyad responsiveness.
Triclosan is associated with breast cancer via oxidative stress and relative telomere length
Authors: Cai Xiaomin , Ning Caibo , Fan Linyun , Li Yanmin , Wang Lu , He Heng , Dong Tianyi , Cai Yimin , Zhang Ming , Lu Zequn , Chen Can , Shi Ke , Ye Tianrun , Zhong Rong , Tian Jianbo , Li Heng , Li Haijie , Zhu Ying , Miao Xiaoping 
Published: May 2023

IntroductionTriclosan (TCS), a widely prescribed broad-spectrum antibacterial agent, is an endocrine-disrupting chemical. The relationship and biological mechanisms between TCS exposure and breast cancer (BC) are disputed. We aimed to examine the correlation between urinary TCS exposure and BC risk and estimated the mediating effects of oxidative stress and relative telomere length (RTL) in the above association.MethodsThis case-control study included 302 BC patients and 302 healthy individuals in Wuhan, China. We detected urinary TCS, three common oxidative stress biomarkers [8-hydroxy-2-deoxyguanosine (8-OHdG), 8-iso-prostaglandin F2α (8-isoPGF2α), 4-hydroxy-2-nonenal-mercapturic acid (HNE-MA)], and RTL in peripheral blood mononuclear cells.ResultsSignificant associations were observed between log-transformed urinary concentrations of TCS, 8-OHdG, HNE-MA, 8-isoPGF2α, RTL, and BC risk, with the odds ratios (95% confidence intervals) being 1.58 (1.32–1.91), 3.08 (1.55–6.23), 3.39 (2.45–4.77), 3.99 (2.48–6.54), and 1.67 (1.35–2.09), respectively. Continuous TCS exposure was significantly positively correlated with RTL, HNE-MA, and 8-isoPGF2α (all p&lt;0.05) but not with 8-OHdG (p = 0.060) after adjusting for covariates. The mediated proportions of 8-isoPGF22α and RTL in the relationship between TCS and BC risk were 12.84% and 8.95%, respectively (all p&lt;0.001).DiscussionIn conclusion, our study provides epidemiological evidence to confirmed the deleterious effects of TCS on BC and indicated the mediating effect of oxidative stress and RTL on the correlation between TCS and BC risk. Moreover, exploring the contribution of TCS to BC can clarify the biological mechanisms of TCS exposure, provide new clues for the pathogenesis of BC, which is of great significance to improving public health systems.
Mental health problems among transition-aged youth with physical disabilities: an initial evaluation
Authors: Amalfi Amanda , Li Jia Yin , Théberge-Lamoureux Vanessa , Tang Carmen , Rinaldi Emilie , Khayargoli Pranamika , Anaby Dana 
Published: May 2023

AimDecreased participation and complex transitions into adulthood among youth with disabilities may impede their well-being. To advance knowledge on the co-occurrence of mental health problems and physical disability, this brief report describes the frequency of mental health problems, measured by the Behavior Assessment System of Children (BASC-3), among transition-aged youth (14–25 years) with physical disabilities and examines the association between mental health problems and sex, age, and number of functional issues.MethodsThirty-three participants completed a demographic questionnaire and the BASC-3. Frequency of BASC-3 scales falling within 3 categories: “within norms”, “at risk”, and “clinically significant” were described. Crosstabs and Chi-square tests were used to examine the association between BASC-3 scales and sex, age (&lt; and ≥ 20), and number of functional issues (&lt; and ≥ 6).ResultsOverall, “somatization”, “self-esteem”, “depression” and “sense of inadequacy” were the most common subscales being at risk. Participants with a higher number of functional issues (≥6) were more likely to fall within “at risk” or “clinically significant” categories across 20 (out of 22) BASC-3 scales, and female participants tended to fall more within “at risk” or “clinically significant” categories for 8 of BASC-3 scales. Younger participants (&lt;20) were ranked in the “at risk” or “clinically significant” categories for 7 scales.ConclusionsFindings lend further support for the occurrence of mental health problems emerging in youth with physical disabilities and highlight initial trends especially across functional levels. Further investigation of such co-occurrences and the factors that affect their development is needed.
Evaluation of Physical Activity Level and Related Factors in Pregnancy During the COVID-19 Period
Authors: Altaş Zeynep Meva , Lüleci Nimet Emel , Hıdıroğlu Seyhan 
Published: May 2023

Objectives: It was aimed to determine the level of physical activity and related factors in pregnant women.Methods: The study is a mixed methods study. The participants are women applied to the pregnancy outpatient clinic of a hospital. The level of physical activity was assessed with the Pregnancy Physical Activity Questionnaire. Sociodemographic questions and seven questions of the International Physical Activity Environment Module were asked. Besides, in-depth interviews were conducted with 14 women.Results: The study was conducted with 304 women. The median age was 29.0 (18.0–40.0) years. The mean total activity and sedentary activity scores were 195.8 ± 107.9 and 37.22 ± 31.08 MET-hours/week, respectively. Pregnant women were mostly involved in light-intensity and housework/caregiving activities. Most of the participants mentioned that they were less active than pre-pregnancy period. The most common reasons for being less active were weakness, fatigue, lack of time and complaints such as low back pain and nausea.Conclusion: More than half of the pregnant women mentioned that they were less active during pregnancy. Thus, interventions should be planned to increase physical activity level of pregnant women.
Glycosyltransferases Expression Changes in Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Grown on Different Carbon Sources
Authors: Vallejo-García Luz Cristina , Sánchez-Olmos María del Carmen , Gutiérrez-Ríos Rosa María , López Munguía Agustín 
Published: May 2023

Leuconostoc mesenteroides strains are common contributors in fermented foods producing a wide variety of polysaccharides from sucrose through glycosyltransferases (GTFs). These polymers have been proposed as protective barriers against acidity, dehydration, heat, and oxidative stress. Despite its presence in many traditional fermented products and their association with food functional properties, regulation of GTFs expression in Ln. mesenteroides is still poorly understood. The strain Ln. mesenteroides ATCC 8293 contains three glucansucrases genes not found in operons, and three fructansucrases genes arranged in two operons, levLX and levC-scrB, a Glycoside-hydrolase. We described the first differential gene expression analysis of this strain when cultivated in different carbon sources. We observed that while GTFs are expressed in the presence of most sugars, they are down-regulated in xylose. We ruled out the regulatory effect of CcpA over GTFs and did not find regulatory elements with a direct effect on glucansucrases in the condition assayed. Our findings suggest that only operon levLX is repressed in xylose by LexA and that both fructansucrases operons can be regulated by the VicK/VicR system and PerR. It is essential to further explore the effect of environmental conditions in Ln. mesenteroides bacteria to better understand GTFs regulation and polymer function.
CyclosporinA derivative as therapeutic candidate for Alport syndrome by inducing mutant type IV collagen secretion
Authors: Kuwazuru Jun , Suico Mary Ann , Omachi Kohei , Kojima Haruka , Kamura Misato , Kaseda Shota , Kawahara Teppei , Hitora Yuki , Kato Hikaru , Tsukamoto Sachiko , Wada Mikiyo , Asano Toshifumi , Kotani Shunsuke , Nakajima Makoto , Misumi Shogo , Sannomiya Yuya , Horizono Jun , Koyama Yuimi , Owaki Aimi , Shuto Tsuyoshi , Kai Hirofumi 
Published: May 2023

Background
Type IV collagen α3,4,5 (α345(IV)) is an obligate trimer that is secreted to form a collagen network, which is the structural foundation of basement membrane. Mutation in one of the genes (COL4A3, A4, A5) encoding these proteins underlies the progressive genetic nephropathy Alport syndrome (AS) due to deficiency in trimerization and/or secretion of the α345(IV) trimer. Thus, improving mutant α345(IV) trimerization and secretion could be a good therapeutic approach for AS.

Methods
Using the nanoluciferase-based platform that we previously developed to detect α345(IV) formation and secretion in HEK293T cells, we screened libraries of natural product extracts and compounds to find a candidate compound capable of increasing mutant α345(IV) secretion.

Results
The screening of >13,000 extracts and >600 compounds revealed that cyclosporin A (CsA) increased the secretion of mutant α345(IV)-G1244D. To elucidate the mechanism of the effect of CsA, we evaluated CsA derivatives with different ability to bind to calcineurin (Cn) and cyclophilin (Cyp). Alisporivir (ALV), which binds to Cyp but not to Cn, increased the trimer secretion of mutant α345(IV). Knockdown studies on Cyps showed that PPIF/CypD was involved in the trimer secretion-enhancing activity of CsA and ALV. We confirmed that other α345(IV) mutants are also responsive to CsA and ALV.

Conclusions
CsA was previously reported to improve proteinuria in AS patients, but due to its nephrotoxic effect, CsA is not recommended for treatment in AS patients. Our data raise the possibility that ALV could be a safer option than CsA. This study provides a novel therapeutic candidate for AS with an innovative mechanism of action, and reveals an aspect of the intracellular regulatory mechanism of α345(IV) that was previously unexplored.
Surgical Treatment of Posttraumatic Deformations of Zygomatico-Orbital Complex
Authors: Велитченко А.Н. , Ластовка А.С. , Павлов О.М. 
Published: May 2023

Наличие посттравматических деформаций костей средней зоны лица приводит к эстетическим проблемам пациентов, меняет привычный внешний вид, во многих случаях приводит к функциональным нарушениям, прежде всего зрения. Учитывая постоянно возрастающие эстетические требования пациентов к своему внешнему виду, настоящее требует совершенствования хирургических методов лечения переломов костей средней зоны лица, в том числе с увеличением показаний к проведению остеосинтеза костей лицевого отдела черепа. Особенностью травмы костей средней зоны лица является наличие выраженных посттравматических отеков и гематом, которые мешают правильной оценке имеющейся костной деформации и тяжести повреждения костей лицевого отдела черепа. С другой стороны, использование хирургических методов лечения в виде репозиций без жесткой фиксации системами мини-пластин или микропластин нередко приводит к вторичным смещениям репонированныхкостных фрагментов, а также к возникновению вторичных деформаций.
The presence of posttraumatic deformities of midfacebones leads to aesthetic problems for patients, change the usual appearance, in many cases leads to functional disorders, primarily of vision. Given the ever-increasing aesthetic requirements of patients for their appearance, the present requires the improvement of surgical methods for treatment of fractures of midfacebones, including an increase in indications for osteosynthesisof bones of facial skull. A feature of trauma of midfacebones is the presence of pronounced posttraumatic edema and hematomas, which interfere with the correct assessment of the existing bone deformity and the severity of damage to bones of facial skull. On the other hand, the use of surgical methods of treatment in the form of repositions without rigid fixation by systems of mini-plates or micro-plates often leads to secondary displacements of the repositioned bone structures and also to occurrence of secondary deformities.
Tongue Cleaning in Oral Hygiene. Part 1
Authors: Попруженко Т.В. , Борис С.П. 
Published: May 2023

Вопрос о чистке языка, время от времени задаваемый стоматологу, требует профессиональных, обстоятельных, не вполне очевидных ответов. Настоящий обзор соответствующей информации, почерпнутой в отечественных и зарубежных источниках, представлен в двух частях. В первой части приведены научные сведения о биологии налета на языке, а также систематизированы широко доступные потребителю суждения о социальных и медицинских задачах, предметах и методах чистки языка, изложены принципы безопасности механического контроля лингвального налета. Во второй части обзора будут представлены результаты анализа научных исследований эффективности чистки языка для решения тех или иных задач, описаны исторические и современные позиции стоматологических сообществ в отношении чистки языка.
The question about tongue cleaning, asked to dentist from time to time, requires professional, thorough, not quite obvious answers. This literature review from national and foreign sources is presented in two parts. The first part provides scientific information about the biology of lingual plaque, systematizes widely available for consumers judgments about the social and medical tasks, subjects and methods of tongue cleaning, outlined the safety principles of mechanical control of lingual plaque. The second part presents the results of scientific research analysis about effectiveness of tongue cleaning for certain tasks, historical and modern positions of the dental community regarding tongue cleaning.
МІХАЛ ГРАБОВСЬКИЙ ЯК ПЕРЕКЛАДАЧ УКРАЇНСЬКОЇ НАРОДНОЇ ТВОРЧОСТІ
Authors: Андерсон Ірина 
Published: May 2023

У статті розглянуто перекладені польською мовою українські козацькі думи та пісні зі збірки Михайла Максимовича 1834 року. Польський літературний критик, письменник доби романтизму, Міхал Грабовський у своїй найвідомішій праці «Література і критика» 1837 року підніс українську народну поезію на щабель зразків світової літератури, козацький епос прирівняв до лицарського епосу, а збірку українських народних пісень Михайла Максимовича визнав зібранням національних шедеврів літератури. Розглянуто такі віршовані пісні: «Ой на морі, на морі синьому», «Гомін, гомін по діброві», «Ой панове-молодці, відкіль ідете?», «Пісні про Свирговського», «Пісні про Морозенка», «Вітер гуде, трава шумить», «Пісня про Богданка», «Туман поле покриває», «Пісня Богуславцю (Гей із устя Дніпра)», «Про козака Байду (А в містечку славним Берестечку)», «А що в тій Чорногорі за вороні коні!», «Ой мала вдова сина сокола», «Наїхали козаки до Марусі в гості», «Повстання Наливайка», «Похід на поляків», «Про Хмельницького та Барабаша», «Про похід Хмельницького в Молдавію», а також думи «Про Івася Коновченка», «Чорноморська буря», «Про Федора Безродного» та «Втеча трьох братів з Азова».
Встановлено, що при перекладі Міхал Грабовський допустив такі погрішності в перекладених поезіях: порушення часового принципу, пропуск строф, недотримання малої / великої літери при тлумаченні, заміна категорії роду іменників, власні доповнення, неправильний переклад певних частин тіла, порушення граматичних форм, зокрема й недотримання правил передавання ступенів порівняння прикметників. Окрім того, не завжди влучно підібрано відповідники до семантики слів із оригіналу тексту, а також фразеологічних одиниць. Однак це жодним чином не применшує заслуги польського літературознавця та не є приводом недооцінювати його сміливий учинок, що мав на меті познайомити польськомовне суспільство з український фольклором.
ANTISEMITISM IN SOVIET UKRAINE: ORIGINS, CONTENT, CONSEQUENCES. HISTORIOGRAPHY OF THE PROBLEM
Authors: Vengerska Victoriуa , Mahaletska Kateryna 
Published: May 2023

The purpose of the article is to analyze and systematize the scientific literature on the study of various aspects of Stalin's state policy of anti-Semitism implemented on Ukrainian lands in the Soviet era.
Methodology. The study used general scientific and special historical methods of scientific knowledge. This made it possible to study and generalize the historiography of anti-Semitism in the Soviet period of national history.
Scientific novelty. For the first time, modern studies of the phenomenon of Soviet anti-Semitism in the Ukrainian territories are systematized on the basis of the thematic principle. The reasons that complicated the process of researching the history of Ukrainian Jews in the Soviet period are analyzed.
Conclusions. In modern historiography, the Jewish issue had to fight for its "place under the sun". The activation of researchers' attention to Judaica, the history of Jews and the Holocaust is associated with the 80-90s of the 20th century. Since the process of formation of Ukrainian historiography was just beginning in the 1990s, the Jewish theme did not immediately become its component. In recent years, the largest number of publications that have appeared in Ukraine are devoted to the problems of the Holocaust and Baby Yar, as its personification. Why was the Holocaust possible? Why did the choice of assimilation strategy not become salvation for the Jews? How did anti-Semitic sentiments grow in the conditions of Stalinist authoritarianism and why do they remain viable at the everyday level? Reflections, searches for answers to these and other questions are presented in modern Ukrainian and foreign historiography, some of them remain open, which preserves prospects for further research.
PENGARUH KEPEMIMPINAN & MOTIVASI TERHADAP KINERJA KARYAWAN DENGAN KOMITMEN ORGANISASI SEBAGAI VARIABEL INTERVENING (STUDI PADA PEKERJAAN KONSTRUKSI KOMANDO DAERAH MILITER I/BUKIT BARISAN)
Authors: Akhmad Rudi  , Ririn Handayani Ririn Handayani 
Published: May 2023

Penelitian ini bertujuan menguji pengaruh kepemimpinan & motivasi terhadap kinerja karyawan dengan komitmen organisasi sebagai intervening. Teknik analisa data menggunakan statistik deskriptif dan analisis verifikatif, sebagai alat analisis digunakan Sctruktural Equational Model yang diproses dengan Software SmartPLS2. Hasil analisis membuktikan pada Konstruksi Komando Daerah Militer I/Bukit Barisan, kepemimpinan berpengaruh positif signifikan terhadap kinerja karyawan; motivasi berpengaruh positif signifikan terhadap kinerja; kepemimpinan berpengaruh positif signifikan terhadap komitmen organisasi; motivasi berpengaruh positif signifikan terhadap komitmen organisasi; komitmen organisasi berpengaruh positif signifikan terhadap kinerja; kepemimpinan berpengaruh positif signifikan terhadap kinerja melalui komitmen organisasi; dan motivasi berpengaruh positif dan tidak signifikan terhadap kinerja karyawan melalui komitmen organisasi.

Kata kunci: Kepemimpinan, Motivasi, Komitmen Organisasi, dan Kinerja