bluuebunny/crossref_metadata_2025_split huggingface dataset:
Patterns of distant metastases in patients with triple‐negative breast cancer—A population‐based study
Authors: Gao Yang , Bian Chuanzhen , Gu Kang , Wang Haiyan , Zhuang Shan , Tang Xiaowen , Zhao Yunian 
Published: June 2023

AbstractThis study provided systematic insights into the patterns of triple‐negative breast cancer (TNBC) distant metastases (DM) and investigated the related elements for the prognosis prediction of TNBC patients based on a large sample. We reviewed eligible patients with TNBC from the SEER database between 2010 and 2015. We also analyzed differences in baseline characteristics among patients with diverse modes of metastasis. Meanwhile, we calculated proportional mortality ratio and expression of proportional trends in different patients. Subsequently, KM analysis was employed to investigate the survival outcomes. Finally, the predictive and prognostic factors of DM were identified. In this study, we included 24 822 TNBC patients, including 1026 DM patients and 23 796 non‐DM patients. At the time of initial diagnosis, 4.1% of patients had DM, and 36.9% had multiple metastases. According to the study, the most common sites of metastasis in DM patients were bone (251 cases) and lung (244 cases), while the least common organ of metastasis was brain (37 cases). Age, grade, T, N, and marital status were deemed as risk elements of DM. T stage, insurance status, marital status, surgery treatment, chemotherapy, number of metastatic sites, and metastatic sites also significantly affected the diagnosis of DM. Our study showed that the most common site of metastasis in TNBC patients with DM was bone and the least common site was brain. Different modes of metastasis have different survival and prognostic characteristics. Thus, our research may have important implications for the clinical practice of TNBC patients in the future.
TSNAXIP1 is required for sperm head formation and male fertility
Authors: Sultana Tasrin , Iwamori Tokuko , Iwamori Naoki 
Published: June 2023

AbstractPurposeTRANSLIN (TSN) and its binding partner TSNAX have been reported to contribute to a wide spectrum of biological activities including spermatogenesis. TSN accompanies specific mRNA transport in male germ cells through intercellular bridges. A testis‐expressed protein TSNAXIP1 was reported to interact with TSNAX. However the role of TSNAXIP1 in spermatogenesis remained unclear. This study aimed to elucidate the role of TSNAXIP1 in spermatogenesis and male fertility in mice.MethodsTSNAXIP1 knockout (KO) mice were generated using the CRISPR‐Cas9 system. The fertility, spermatogenesis, and sperm of TSNAXIP1 KO males were analyzed.ResultsTSNAXIP1, and especially its domains, are highly conserved between mouse and human. Tsnaxip1 was expressed in testis, but not in ovary. TSNAXIP1 KO mice were generated, and TSNAXIP1 KO males were found to be sub‐fertile with smaller testis and lower sperm count. Although no overt abnormalities were observed during spermatogenesis, lack of TSNAXIP1 induced sperm head malformation, resulting in a unique flower‐shaped sperm head. Moreover, abnormal anchorage of the sperm neck was frequently observed in TSNAXIP1 null sperm.ConclusionA testis‐expressed gene TSNAXIP1 has important roles in sperm head morphogenesis and male fertility. Moreover, TSNAXIP1 could be a causative gene for human infertility.
Theℒ1controller synthesis for piecewise continuous nonlinear systems via set invariance principles
Authors: Choi Hyung Tae , Kim Jung Hoon 
Published: June 2023

AbstractThis article provides a synthesis method of the controller for piecewise continuous nonlinear systems in terms of set invariance principles. Following the arguments of Filippov's differential equations, solutions of piecewise continuous differential equations are first characterized by set‐valued functions. Based on such characteristics of solutions equipped with set‐valued functions, the performance of piecewise continuous nonlinear systems, that is, the gain from the associated disturbance to regulated output, is formulated. To clarify the existence of a controller such that the resulting closed‐loop system satisfies the performance in the presence of piecewise continuity, the so‐called generalized controlled invariance domain is proposed. Taking this advanced argument allows us to establish a synthesis procedure for the controller by showing a lower‐semicontinuity of the set‐valued functions involved in the generalized controlled invariance domain. Finally, some numerical examples are provided to evaluate the validity of the existence condition for the controller.
Botfly Myiasis after Travel to Bolivia
Authors: Chattopadhyay Aheli , Wang Jason F. , Wei Maria L. 
Published: June 2023

Abstract
Following a trip to Bolivia, a 32-year-old woman developed a left lower leg ulcer with a sensation of movement within the lesion. After being seen by four primary care providers, she was referred to dermatology 7 weeks after her return from Bolivia. At that time, she was found to have a 5 mm weeping ulcer, with a live larva visible at the base. We conducted a punch biopsy for botfly removal, after which the patient healed well. Herein we discuss the ways in which clinical presentation, history of travel, dermoscopy, and ultrasound can contribute to diagnosing botfly myiasis. While treatment of botfly infestation is not required, we discuss the importance of shared decision-making in considering treatment, as well as methods for extraction, including mechanical or surgical removal, which may help to reduce patient anxiety and the risk for secondary infection. As global travel resumes to levels prior to the Covid-19 pandemic, it is important for dermatologists to be aware of the presenting symptoms and treatment of tropical skin disorders.
Acidity: A Key Parameter in Zeolite‐Templated Carbon Formation
Authors: Aumond Thibaud , Vezin Hervé , Batonneau‐Gener Isabelle , Compère Steven , Pouilloux Yannick , Le Person Annaig , Moissette Alain , Sachse Alexander 
Published: June 2023

AbstractThis work reveals the crucial role of zeolite acidity in the synthesis of zeolite‐templated carbons (ZTCs). While textural and chemical properties appear to be independent from acidity at a given synthesis temperature, the spin concentration in hybrid materials appears to be strongly impacted by the zeolite acid site concentration. The electrical conductivity of the hybrids and resulting ZTCs are closely related to the spin concentration in the hybrid materials. The amount of zeolite acid sites hence fundamentally impacts the electrical conductivity of the samples that spans over a range of four magnitudes. Electrical conductivity reveals as key parameter to describe the quality of ZTCs.
2D–3D‐Convertible, pH‐Responsive Lipid Nanosheets
Authors: Zhang Wancheng , Takahashi Shutaro , Shimada Naohiko , Maruyama Atsushi 
Published: June 2023

Abstract2D nanosheets self‐assembled with amphiphilic molecules are promising tools for biomedical applications; yet, there are challenges to form and stabilize these nanosheets under complex physiological conditions. Here, the development of lipid nanosheets with high structural stability that can be reversibly converted to cell‐sized vesicles by changes in pH within the physiological range robustly, are described. The system is controlled by the membrane disruptive peptide E5 and a cationic copolymer anchored on lipid membranes. It is envisioned that nanosheets formed using the dual anchoring peptide/cationic copolymer system can be employed in dynamic lipidic nanodevices, such as the vesosomes described here, drug delivery systems, and artificial cells.
Modulating Ionic Transport and Interface Chemistry via Surface‐Modified Silica Carrier in Nano Colloid Electrolyte for Stable Cycling of Li‐Metal Batteries
Authors: Lim Minhong , An Hyeongguk , Seo Jiyeon , Lee Mingyu , Lee Hyuntae , Kwon Hyeokjin , Kim Hee‐Tak , Esken Daniel , Takata Ryo , Song Hyun A , Lee Hongkyung 
Published: June 2023

AbstractTailoring the Li+ microenvironment is crucial for achieving fast ionic transfer and a mechanically reinforced solid–electrolyte interphase (SEI), which administers the stable cycling of Li‐metal batteries (LMBs). Apart from traditional salt/solvent compositional tuning, this study presents the simultaneous modulation of Li+ transport and SEI chemistry using a citric acid (CA)‐modified silica‐based colloidal electrolyte (C‐SCE). CA‐tethered silica (CA‐SiO2) can render more active sites for attracting complex anions, leading to further dissociation of Li+ from the anions, resulting in a high Li+ transference number (≈0.75). Intermolecular hydrogen bonds between solvent molecules and CA‐SiO2 and their migration also act as nano‐carrier for delivering additives and anions toward the Li surface, reinforcing the SEI via the co‐implantation of SiO2 and fluorinated components. Notably, C‐SCE demonstrated Li dendrite suppression and improved cycling stability of LMBs compared with the CA‐free SiO2 colloidal electrolyte, hinting that the surface properties of the nanoparticles have a huge impact on the dendrite‐inhibiting role of nano colloidal electrolytes.
Anion Exchange Facilitates the In Situ Construction of Bi/BiO Interfaces for Enhanced Electrochemical CO2‐to‐Formate Conversion Over a Wide Potential Window
Authors: Zhao Shulin , Qin Yue , Wang Xuerong , Wang Chun , Chen Xin , Wang Yu , Yu Jie‐Xiang , Liu Xiaojing , Wu Yuping , Chen Yuhui 
Published: June 2023

AbstractElectrochemical reduction of CO2 (CO2RR) into value‐added products is a promising strategy to reduce energy consumption and solve environmental issues. Formic acid/formate is one of the high‐value, easy‐to‐collect, and economically viable products. Herein, the reconstructed Bi2O2CO3 nanosheets (BOCR NSs) are synthesized by an in situ electrochemical anion exchange strategy from Bi2O2SO4 as a pre‐catalyst. The BOCR NSs achieve a high formate Faradaic efficiency (FEformate) of 95.7% at −1.1 V versus reversible hydrogen electrode (vs. RHE), and maintain FEformate above 90% in a wide potential range from −0.8 to −1.5 V in H‐cell. The in situ spectroscopic studies reveal that the obtained BOCR NSs undergo the anion exchange from Bi2O2SO4 to Bi2O2CO3 and further promote the self‐reduction to metallic Bi to construct Bi/BiO active site to facilitate the formation of OCHO* intermediate. This result demonstrates anion exchange strategy can be used to rational design high performance of the catalysts toward CO2RR.
Insights into Electrode Architectures and Lithium‐Ion Transport in Polycrystalline V2O5 Cathodes of Solid‐State Batteries
Authors: Yu Zhenjiang , Shan Hongmei , Zhong Yunlei , Hong Guo , Hui Kwan San , Zhang Xia , Hui Kwun Nam 
Published: June 2023

AbstractPolymer‐based solid‐state batteries (SSBs) have received increasing attentions due to the absence of interfacial problems in sulfide/oxide‐type SSBs, but the lower oxidation potential of polymer‐based electrolytes greatly limits the application of conventional high‐voltage cathode such as LiNixCoyMnzO2 (NCM) and lithium‐rich NCM. Herein, this study reports on a lithium‐free V2O5 cathode that enables the applications of polymer‐based solid‐state electrolyte (SSE) with high energy density due to the microstructured transport channels and suitable operational voltage. Using a synergistic combination of structural inspection and non‐destructive X‐ray computed tomography (X‐CT), it interprets the chemo–mechanical behavior that determines the electrochemical performance of the V2O5 cathode. Through detailed kinetic analyses such as differential capacity and galvanostatic intermittent titration technique (GITT), it is elucidated that the hierarchical V2O5 constructed through microstructural engineering exhibits smaller electrochemical polarization and faster Li‐ion diffusion rates in polymer‐based SSBs than those in the liquid lithium batteries (LLBs). By the hierarchical ion transport channels created by the nanoparticles against each other, superior cycling stability (≈91.7% capacity retention after 100 cycles at 1 C) is achieved at 60 °C in polyoxyethylene (PEO)‐based SSBs. The results highlight the crucial role of microstructure engineering in designing Li‐free cathodes for polymer‐based SSBs.
Ecosystem sustainability and conservation of waste natural fiber strengthen epoxy composites for lightweight applications
Authors: Poyyamozhi Natesan , Sivanantham Arunachalam , Mukilarasan Nedunchezhiyan , Gopal Kaliyaperumal , De Poures Melvin Victor , Venkatesh Rathinavelu , Naveen Subbaiyan , Perumal Muthumari 
Published: June 2023

AbstractIn recent days, the automobile, aerospace, and marine sectors are imposed to search the similar quality alternative material with desired mechanical and wear characteristics obtained by using natural fiber extracted from environmental wastes. The current investigational characteristics study focuses to increase the mechanical properties of composite by using NaOH‐treated natural fiber like jute and sisal bonded with epoxy resin via the wet filament technique. The four different positions of fibers like the jute‐sisal fiber were dipped with epoxy resin and waved as random (multi‐directional), 0° (unidirectional), 90° (bi‐directional), and interlock position. The developed natural fiber composites were subjected to tensile, impact, and flexural strength made by ASTM procedure. The composite prepared with interlock position showed higher tensile, impact, and flexural strength 49.51 ± 1.51 MPa, 12 ± 0.98 J, and 57.31 ± 1.98 MPa respectively and improved by 12%, 33.3%, and 10% as compared to random (multi‐directional) composite. So the developed composites were enhanced by the conservation of jute/sisal fiber bonded with epoxy as interlocking distribution is utilized for lightweight applications and the conservation of waste natural fiber retained the ecosystem sustainability.
Reconstructing radar reflectivity by integrating GPM and INSAT‐3D observations for near real‐time monitoring of convective storms over India
Authors: Mishra Anoop Kumar , Tomar Chander Singh , Kumar Gajendra , Bhan Subhash Chander 
Published: June 2023

AbstractThis study focuses on integrating dual‐frequency precipitation radar (DPR) observations on‐board the Global Precipitation Mission with the storm index from INSAT‐3D for the development of reconstructed radar reflectivity. Performance of the derived product was tested against the independent DPR observations. A correlation coefficient of 0.81 is reported between the reconstructed radar reflectivity and the DPR observations. Derived reconstructed reflectivity is shown to be an excellent product for the weather monitoring over the regions without radar coverage.
Local discontinuous Galerkin method on graded meshes for a third‐order singularly perturbed problem
Authors: Yan Li , Cheng Yao 
Published: June 2023

AbstractWe consider the local discontinuous Galerkin (LDG) method for a third order singularly perturbed problem with different kinds of boundary layer. On graded Duran‐Shishkin and Duran type meshes, we prove optimal order error estimate in the energy‐norm which is valid uniformly up to a logarithmic factor. Numerical experiments are given to confirm our theoretical findings.
A Crack in the Track of the Hubble Constant
Authors: Gueguen Marie 
Published: June 2023

AbstractMeasuring the rate at which the universe expands at a given time–the ‘Hubble constant’– has been a topic of controversy since the first measure of its expansion by Edwin Hubble in the 1920s. As early as the 1970s, Sandage and de Vaucouleurs have been arguing about the adequate methodology for such a measurement. Should astronomers focus only on their best indicators, e.g., the Cepheids, and improve the precision of this measurement based on a unique object to the best possible? Or should they “spread the risks”, i.e., multiply the indicators and methodologies before averaging over their results? Is a robust agreement across several uncertain measures, as is currently argued to defend the existence of a ‘Hubble crisis’ more telling than a single 1% precision measurement? This controversy, I argue, stems from a misconception of what managing the uncertainties associated with such experimental measurements require. Astrophysical measurements, such as the measure of the Hubble constant, require a methodology that permits both to reduce the known uncertainties and to track the unknown unknowns. Based on the lessons drawn from the so-called Hubble crisis, I sketch a methodological guide for identifying, quantifying and reducing uncertainties in astrophysical measurements, hoping that such a guide can not only help to re-frame the current Hubble tension, but serve as a starting point for future fruitful discussions between astrophysicists, astronomers and philosophers.
Green Marketing as Manifest Performance of Ethical Judgment
Authors: Bengtson Erik , Mossberg Oskar 
Published: June 2023

AbstractThis chapter concludes the book’s discussion and emphasizes the need for discursive conditions and a constructive marketing critique that encourages virtuous marketing practices. The chapter also relates the virtue-framework to the field of marketing ethics, as well as other strands of research, and suggests avenues for future interdisciplinary work. We argue that rhetorical scholarship can contribute to the collaborative effort of steering market dynamics in more sustainable directions.
Female Migration and Stay-Behind Children in Bangladesh
Authors: Luna Sabnam Sarmin 
Published: June 2023

AbstractIn migration studies, male migrants and their stay-behind families, including women and children have been an area of sustained academic investigation in the Global South. The unaccompanied children of female migrants remain, however, an area of peripheral interest in the existing literature. Millions of South Asian female migrants work in two major destination regions: the GCC countries and Southeast Asia. They are often married with children and their traditional role as mothers is transferred to and executed by other members of the extended family, giving rise to an exciting area of migration research in the global South in general and in South Asia in particular. This paper attempts to address this relatively under-studied field of South-South migration by investigating the stay-behind families of female migrants in Bangladesh with a focus on their unaccompanied children.
Sustainable Development of Railway Corridors: Methods and Models for High Speed Rail (HSR) Demand Analysis
Authors: Russo Francesco , Sgro Domenico , Musolino Giuseppe 
Published: June 2023

AbstractThe realization of High Speed Rail (HSR) lines generates different type of effects that have been observed and studied in the scientific literature in last decades. The paper focuses on the travel demand models to estimate the effects of HSR on passenger mobility. The HSR travel demand may be segmented into three main components: diverted demand from other modes, or from other rail services, to HSR; induced demand, which can be direct and indirect; economy-based demand growth. The aim is to analyse and highlight the actual trend of scientific publications on the HSR demand analysis, thus identify the existing research gaps and the needs inside this trend, so the necessary future directions of research.
Methodologies for Sustainable Development of TEN-T/RFC Corridors and Core Ports: Estimation of Time-Series Economic Impact
Authors: Musolino Giuseppe , Cartisano Antonio , Fortugno Giuseppe 
Published: June 2023

AbstractThe container revolution in the last decades of the 20th century determined the arise of container ports. They further evolved in the so-called third-generation ports, becoming generators of value added due to the manipulation of goods in transit. The increase of value added in third-generation ports is amplified in core ports connected to TEN-T/RFC corridors, where Special Economic Zones (SEZs) and the three pillars of smartness (ICT, Transport and Energy) are present. The paper deals with time-series models for the estimation of economic impact of a SEZ in an underdeveloped region of EU. The test case is the Calabria region (Italy). SEZ in Calabria has its fulcrum in the industrial area close to the transhipment hub port of Gioia Tauro. The economic impacts of the SEZ were quantified through two variables: exports and employment of industrial firms settled in Calabria. The comparison of two scenarios (Do-Nothing scenario and SEZ) shows relevant positive impacts in the SEZ one. Future developments concern the calibration and validation of multi-variate time-series models from observations provided by worldwide SEZs.
Entanglement and geometry from subalgebras of the Virasoro algebra
Authors: Caputa Pawel , Ge Dongsheng 
Published: June 2023

Abstract
In this work we study families of generalised coherent states constructed from SL(2,R) subalgebras of the Virasoro algebra in two-dimensional conformal field theories. We derive the energy density and entanglement entropy and discuss their equivalence with analogous quantities computed in locally excited states. Moreover, we analyze their dual, holographic geometries and reproduce entanglement entropies from the Ryu-Takayanagi prescription. Finally, we outline possible applications of this universal class of states to operator growth and inhomogeneous quenches.
A two-dimensional string cosmology
Authors: Rodriguez Victor A. 
Published: June 2023

Abstract
We study two-dimensional string theory on a time-dependent background, whose worldsheet description consists of Liouville theory at central charge c = 1 and Liouville theory at central charge c = 25, together with the conformal ghosts. We compute the tree-level three-point and four-point components of the cosmological wavefunction in string perturbation theory. The latter is evaluated numerically by decomposing the Liouville four-point correlation functions into Virasoro conformal blocks and three-point function coefficients and integrating over the moduli space of the four-punctured sphere string diagram. This computation numerically confirms a surprisingly simple conjectural result for the four-point wavefunction component whose physical interpretation remains to be clarified.
Accommodating muon (g − 2) and leptogenesis in a scotogenic model
Authors: Alvarez A. , Banik A. , Cepedello R. , Herrmann B. , Porod W. , Sarazin M. , Schnelke M. 
Published: June 2023

Abstract
We present a detailed study of a scotogenic model accommodating dark matter, neutrino masses and the anomalous magnetic moment of the muon while being consistent with the existing constraints on flavour violating decays of the leptons. Moreover, this model offers the possibility to explain the baryon asymmetry of the Universe via leptogenesis. We determine the viable regions of the model’s parameter space in view of dark matter and flavour constraints using a Markov Chain Monte Carlo setup combined with a particular procedure to accommodate neutrino masses and the anomalous magnetic moment of the muon at the same time. We also discuss briefly the resulting collider phenomenology.
Kac-Moody symmetry in the light front of gauge theories
Authors: González Hernán A. , Labrin Oriana , Miskovic Olivera 
Published: June 2023

Abstract
We discuss the emergence of a new symmetry generator in a Hamiltonian realisation of four-dimensional gauge theories in the flat space foliated by retarded (advanced) time. It generates an asymptotic symmetry that acts on the asymptotic fields in a way different from the usual large gauge transformations. The improved canonical generators, corresponding to gauge and asymptotic symmetries, form a classical Kac-Moody charge algebra with a non-trivial central extension. In particular, we describe the case of electromagnetism, where the charge algebra is the U(1) current algebra with a level proportional to the coupling constant of the theory, κ = 4π2/e2. We construct bilinear generators yielding Virasoro algebras on the null boundary. We also provide a non-Abelian generalization of the previous symmetries by analysing the evolution of Yang-Mills theory in Bondi coordinates.