bluuebunny/crossref_metadata_2025_split huggingface dataset:
An Efficient Privacy Preserving Scheme for Internet of Things Environment
Authors: Taha Mohammad Bany 
Published: January 2023

Abstract
While Internet of Things (IoT) systems, including cloud-enabled IoT systems, are becoming the norm, ensuring the security and privacy of data without impacting performance remains challenging. In this paper, we demonstrate how one can outsource attribute-based encryption (ABE) operations (e.g., encryption and decryption) to proxy servers in order to reduce the computation overhead of encryption and decryption. Our proposed scheme is also designed to incur minimal storage overhead of the ciphertext (CT), by generating constant ciphertext, regardless of the number of access policy attributes required for encryption. We also evaluate the performance of our proposed scheme and demonstrate that our scheme is more efficient than two other schemes.
Evaluation of GPS Signal Vulnerabilities against Time Synchronization Attacks
Authors: Bagheri Z. , Orouji N. , Mosavi Mohammad Reza 
Published: January 2023

Abstract

A spoofing attack is an intervention aimed at forcing the GPS receiver to obtain and track invalid navigation data. Time Synchronization Attack (TSA) is a type of spoofing attack that changes the receiver clock information, such as clock offset and drift. The purpose of TSA is to create an error in the estimated time of the receiver. These attacks usually target static receivers that use GPS signals for their time-synchronization applications. One of the main countermeasures for any security vulnerabilities is comprehending the process of thread generation and weak points of the system. In this research, for the first time, the TSA generation process is discussed and explained in detail. The proposed method demonstrates the feasibility of a spoof attack on the GPS receiver. The attack is defined as an optimization problem that aims to maximize the receiver clock offset error while maintaining the receiver position. The decision variables in the optimization problem are the coordinates of the receiver and the satellite's ephemerides variables. The constraints are such that the decision variables and satellite positions calculated from solving the optimization problem are close to pre-attack values to avoid possible detection schemes that examine large mutations in the values of these variables. Due to the ability to solve complex problems, simple concepts, and easy implementation of Metaheuristic Optimization Algorithms (MOA), Chimp Optimization Algorithm (ChoA), Grey Wolf Optimization (GWO) and Particle Swarm Optimization (PSO) algorithms are exploited. According to the achieved solutions, the maximum modification in the receiver clock offset is 1.6 ms, which is a severe attack based on IEEE C37.118 standard. This result is achieved despite a change of 10 meters in the coordinates of the receiver position.
Numerical solution of nonsingular fuzzy LR algebraic linear equations
Authors: Zhou Hongyi 
Published: January 2023

Abstract
In order to solve a fuzzy LR algebraic linear equation, a linear programme with much larger dimension than the original one is employed in [14]. Thus it is a expensive method to solve the fuzzy LR algebraic equations. In this paper, By studying the algebraic structure of the fuzzy equations, a much cheaper method is proposed. Numerical tests show the efficiency of our method. Here our method can also be used to study the conditions of the solution existence.
Traditional Chinese medicine formula Xiaoyaosan alleviates autistic behaviors and anxiety behaviors in valproic acid-induced autistic rats
Authors: Li Yanyan , Yang Junjie , Li Honglei , Xu Chengming , Li Enyao , Dong Xianwen 
Published: January 2023

Abstract
Background
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is correlated with anxiety behavior. This study aimed to investigate the effect of Xiaoyaosan (XYS) on anxiety behavior in autism rats and its potential mechanism.
Materials and Methods
The autistic rat model was established by intraperitoneal injection of pregnant rats with sodium valproic acid (VPA) at 12.5 days of pregnancy. The newborn rats (n = 15 in each group) were given XYS solution gavage daily for 21 days. The autistic behaviors were identified by the marble-burying behavior test (MBT), ultrasonic vocalization (USV) test, three-chamber social interaction task (TCT), and novel object recognition (NOR) task. The anxiety behaviors were detected by open field test (OFT), elevated plus maze (EPM), and sucrose preference test (SPT). Heart rate variability (HRV) was used to detect the changes in the autonomic nerve. The expression of Ionized calcium-binding adaptor molecule 1 (Iba-1) in microglia of the hippocampus and amygdala was detected by immunohistochemistry.
Results
Compared with the control group, the number of buried marbles in MBT was increased, the number of vocalizations at 50 kHz in the USV test was reduced, the social ability in the TST was reduced, and the exploration time and distance of new objects in NOR task were reduced in the VPA group. In the OFT, the activity time in the central zone was reduced, the open arm activity time in EPM was reduced, and the sucrose consumption rate in SPT was reduced in autistic rats. The autonomic sympathetic balance of autistic rats was impaired. In hippocampus and amygdala regions, the number of Iba-1 positive cells was increased in VPA-induced rats. After XYS treatment, the above effects caused by VPA were reversed.
Conclusion
XYS could improve autism and anxiety behaviors. It could also maintain the balance of sympathetic and parasympathetic nerves in autistic rats. Its mechanism may be related to the inhibition of the activation of microglia in the hippocampus and amygdala.
Design and Development of Open Source Software Solution for Hyperspectral Data Simulation: Hydas.
Authors: Tiwari Varun , Kumar Vinay , Pandey Kamal , Anand Shivesh , Ranade Rigved , Singh Mohit , Agrawal Shefali 
Published: January 2023

Abstract
Multispectral remote sensing data is available with broad spectral bands in the wavelength range of Visible-NIR-SWIR, and finds its applications in assessment of Land Use Land Cover classes (LULC). There are plenty of onboard sensors which are providing these datasets regularly. However, for detailed LULC classification there is a requirement of distinguishing spectrally similar land cover features, which is possible through hyperspectral data. These datasets are spectrally rich and are available with narrow spectral bandwidth but the availability of such datasets is limited. This is due to requirement of sophisticated detectors and high storage, which makes the acquisition of these datasets challenging. Therefore, there is a opportunity to utilize the available multispectral data for generating hyperspectral data. Existing spectral reconstruction technique is used for simulating hyperspectral bands from multispectral bands in combination with ground spectra. In this study, an attempt has been made to develop a software solution for automating the simulation of hyperspectral data using multispectral data in an open source platform. The developed software solution (HyDAS) consists of modules for satellite data visualization, spectral library creation, spectral unmixing and hyperspectral data simulation. HyDAS toolbox is successfully tested for simulating hyperspectral data from EO-1 ALI multispectral data. The simulated results were validated using the available EO-1 Hyperion data and results were satisfactory with similarity being 80–90%. This open source solution was also tested for simulating hyperspectral bands from EO-1 ALI and Indian Satellite (LISS III & LISS IV) multispectral datasets, the results obtained were satisfactory for species level classification
Role of the lipid bilayer at the dielectric relaxations in human erythrocytes
Authors: Ivanov Ivan T. , Paarvanova Boyana Kaancheva 
Published: January 2023

AbstractUsing the dielectric changes in red blood cells (RBCs) at the temperature of spectrin dissociation and denaturation,TA, two dielectric relaxations have been detected on spectrin network, βsprelaxation at 1.4 MHz and γ1sprelaxation at 9 MHz. In this study, the βsprelaxation was linearly strengthened on increasing the ion accumulation at either side of RBC plasma membranes, while the strength of γ1sprelaxation remained unaffected. In Triton shells, produced by mild extraction of RBC ghost membrane lipids by Triton-X-100 (up to 0.1%) and in RBCs, treated by acid medium (pH 5.2), known to disconnect the glycophorin C integral protein from the actin-spectrin junction, the βsprelaxation was strongly to fully inhibited while γ1sprelaxation was preserved. In RBCs, acid-treated RBCs, RBC ghost membranes and Triton-X shells the capacitance contribution and dielectric loss curve of spectrin network were both positive for βsprelaxation and negative for γ1sprelaxation. The above results support the view that βsprelaxation exhibits piezo effect on spectrin network prior toTA, powered by the electrodeformation of lipid membrane mainly through the glycophorin C-actin-spectrin bridge. This piezo effect adds strength (~ 25%) to the interfacial polarization of RBC lipid membrane and could be adjuvant factor in the elasticity and flicker of RBC membrane. The results and the amended equivalent circuit of RBC suspension support the claim that γ1sprelaxation reflects direct interaction and resonance of the field with the natural oscillations of dipoles (segments) of spectrin tetramers.
Load-dependent dynamic model of spur gear considering effects of oil film
Authors: Cao Zheng , Rao Meng , Chen Zaigang 
Published: January 2023

Abstract
Gear system is usually lubricated to generate an oil film to avoid dry contact at the mesh interface. As the oil film separates the engaging gear teeth, its effect on the transmission error (TE) is opposite to the teeth elasticity. How to consider the combined influence of the oil film and the tooth elasticity on the TE, and further on the dynamic performance of gears, is still not revealed completely. In this paper, a new mesh stiffness (MS) involving the effect from the oil film and the tooth elasticity is defined, and a nonlinear dynamic model of a spur gear system with developed MS and drive-side and back-side contact is proposed. The effect of the oil film on the dynamic responses of the gear pair is revealed by comparing the received results with that from the dry contact situation and the experiment. It is indicated that the oil film will affect the effective MS and dynamic transmission error (DTE) of the gear system, especially under the situation with the light load. For a tip relived gear pair, the dynamic load sharing ratio (DLSR) between teeth pairs changes significantly when the lubrication is considered.
A Computed Tomography and Dissection Study of a Unique Ychsma Burial Bundle from the site of Pachacamac, Peruvian Central Coast
Authors: Owens Lawrence S. , Eeckhout Peter A. 
Published: January 2023

Abstract
Computed tomography (CT) scans of funerary bundles have become the convention for mummy studies, especially in Andean contexts. Increasingly high-resolution 3D imaging – as well as ethical issues surrounding the treatment of human remains, has led to the increasing conviction that mummy studies should be carried out using solely digital approaches. However, the fact that these approaches are non-invasive inevitably stymies our understanding of how accurate they are, compared to traditional unwrapping. A large, complex Ychsma bundle (dated to AD1020-1150) was recovered from Pachacamac, Peru, in 2018, and was analysed using a dual approach. A series of CT images were scored for bundle structure, body position, element presence, and anatomy/pathology; the bundle was then dissected and the data was compared. CT imaging performed well for body position, element presence and certain aspects of anatomy/pathology. However, the presence of radio-opaque inclusions following the internal deterioration in antiquity served to obscure various elements, while the CT was also unable to distinguish any of the layers of textile and botanical wrappings or any artefacts within them. The CT was also unable to determine that the bundle contained two individuals; the original individual had been partially removed and other elements incorporated, but as there was no element duplication the CT imaging could not differentiate the individuals. In addition to providing new information concerning bundle reprocessing and the use of trophy items among the Ychsma, this is both a support and cautionary tale towards the use of radiographic imaging in the analysis of Andean bundles.
Potentials of Single Nucleotide Polymorphisms and Genetic Diversity Studies at HSP90AB1 Gene in Nigerian White Fulani, Muturu and N’Dama Cattle Breeds
Authors: De Campos John , Onasanya Gbolabo , Ubong Akpan , Yusuff Afolabi , Adenaike Adeyemi , Mohammed Afolarin , Ikeobi Christian 
Published: January 2023

Abstract
The study was aimed at genetic characterization of the (Heat Shock Protein 90AB1) HSP90AB1 gene in the Muturu, N’Dama and White Fulani Nigerian cattle. Total number of 200 blood samples were collected from white Fulani, muturu and N’Dama breeds of cattle out of which 20 samples each were used for the wet laboratory experiment. DNA was extracted from the blood samples using the Zymo-bead extraction kit and DNA sequencing of our samples was performed. A total number of 9 and 11 Single nucleotide polymorphisms (SNPs) were detected using the codon code aligner software within exons 5–6 and 12–13 of the HSP90AB1 gene. ARLEQUIN 2.0001 software was used to estimate the basic population genetic statistics while the DnaSP version5.10.01 was used to estimate the genetic diversity indices. In exons 5–6, the N’Dama cattle had the highest (5) for number of SNPs and genetic diversity indices while other breeds including White Fulani and Muturu had the least (2) number of SNPs and genetic diversity indices breeds. In exons 12–13, White Fulani had the highest (7) for the numbers of SNPs and genetic diversity indices while Muturu had the least (1) number of SNPs and genetic diversity indices. Some of the SNPs identified at these loci were shared by the breeds, suggesting the likelihood of shared ancestral alleles and similar functions. The study concluded that the HSP90AB1 was polymorphic and highly diverse in Nigerian cattle breeds.
Study on the resolution of DC resistivity sounding exploration with differential array and integral array in layered media
Authors: Ling Jiaxuan , Dai Shikun , Zhou Yinming 
Published: January 2023

Abstract
In order to study the exploration device to improve the resolution of DC resistivity exploration, we introduced the differential array and integral array, and gave the basic principle and apparent resistivity expression of these two arrays. Based on the forward and inversion theory in layered media, we have demonstrated the exploration resolution of these two arrays through several examples. The results show that, compared with other arrays, the differential array has better sensitivity and resolution to layered media. The integral array and dipole-dipole array have the same resolution to the underground, which is inferior to the differential array, and the integral array has a higher signal-to-noise ratio than the dipole-dipole array.
Pattern of CD4 + T cell recovery and determinants of HIV infected individuals receiving highly active antiretroviral treatment in Mekelle Hospital, Tigray Northern Ethiopia; Retrospective study
Authors: Weldemhret Letebrhan , Aregay Abraham , Bekurtsion Hadish , Gebreegziabher Gebremicheal , Asmelash Tsehaye , Hagos Dawit Gebreegziabher 
Published: January 2023

Abstract
Background: With the advent of antiretroviral treatment, HIV related morbidity and mortality have tremendously decreased. However, some HIV patients on ART don’t optimally respond to the ART regimen to restore the immunity. This study was aimed to determine the pattern of CD4+ T cell recovery and determinants of HIV infected individuals receiving the ART in Mekelle Hospital, Tigray northern Ethiopia.
Methods: A hospital based retrospective cross-sectional study was conducted from January, 2010 to August, July 2020 among HIV positive individuals on ART follow up. Data were collected using pre-tested structured questionnaire by trained data collector. Statistical analysis was performed using SPSS V. 20. Bivariate and multivariate analyses were performed to identify the possible predictors for immune reconstitution after ART administration. P-values < 0.05 was considered statistically significant.
Results: Of the total 424 study participants, 248(58%) were females. The mean age of the study participants was 37+9 (mean + sd). The median time of ART follow up was 60 (IQR: 36-84) months and the recent median CD4+ T-cell count was 388 (IQR; 254-527) cells/µl. The CD4 cell count increment compared to pre-ART was 166 cells/µl of blood. Age ranges 25-34 years (AOR 2.62, 95%CI: 0.82-8.35), CD4+ T-cell count >200 cells/µl at baseline (AOR 3.53, 95%CI: 2.23-5.58), duration of ART follow up at 12, 48 and 49 and above months respectively (AOR 8.053, 95%CI:1.45-44.84; 4.82, 95%CI:1.16-20.11); and (AOR 6.36, 95%CI:1.63-24.77), and TDF-3CT-Efv ART regimen combination (AOR 2.29, 95%CI:1.32-3.97) were found predictors significantly associated with CD4+ T-cell recovery after long term ART uptake, which characterized by >350 cells/µl increments.
Conclusions: The immune restoration of HIV positive individuals depends on the length of ART follow up time and CD4+ T-cell level during the initiation. Moreover, individuals who were taking TDF-3CT-Efv ART drug combination demonstrated a rapid CD4+ T-cell restoration than these who were taking other ART drug regimens.
Comparative function of blacklight and visual light sources in capturing Harmonia axyridis in the field and laboratory conditions; effect of color polymorphism
Authors: Farhoudi Farhad , Sahragard Ahad , Hosseini Reza , Saboori Atefeh 
Published: January 2023

Abstract

Light trapping is one of the most popular sampling methods for monitoring pests’ populations in IPM programs. Harmonia axyridis (Coleoptera: Coccinellidae), which is a voracious aphid predator, needs to be monitored for several reasons; e.g. for its function as an invasive alien species newly appeared in many non-native countries. Lots of studies and observations show that this ladybird is significantly attracted to blacklight traps. Two major color morphs of H. axyridis (melanic and nonmelanic) appear with different ratios in different populations. In this study, the outcome of two sampling methods, including light trapping and foliage beating were evaluated in terms of the color morph combination and sex ratio in the field. Also, two types of light sources (blacklight (UV) and visual light LED) were compared in attracting the two color morphs in the laboratory conditions. Field results, where the ladybirds could fly towards the light source, indicated that blacklight trap captures less melanic individuals compare to mercury light trap and foliage beating, while there was no difference between the two latter methods. Also sex ratios were not different among the sampling methods. However, blacklight (UV) and visual light sources did not show any effect on attracting the two morphs in laboratory conditions, where the ladybirds could only walk towards the light sources. Comparing the results from field and laboratory experiments suggest that H. axyridis shows different phototaxic reactions based on its locomotion options.
A case-control study of the association between the gut microbiota and colorectal cancer: exploring the roles of diet, stress, and race
Authors: Carson Tiffany L , Byrd Doratha A , Smith Kristen S , Carter Daniel , Abaskaron Michael , Little Rebecca B , Holmes Sh'Nese Townsend , Pol William J van Der , Lefkowitz Elliot J , Morrow Casey D , Fruge Andrew D , Gomez Maria 
Published: January 2023

Abstract
Background
The gut microbiota is associated with risk for colorectal cancer (CRC), a chronic disease for which racial disparities persist with Black Americans having a higher risk of CRC incidence and mortality compared to other groups. Given documented racial differences, the gut microbiota may offer some insight into previously unexplained racial disparities in CRC incidence and mortality. A case-control analysis comparing 11 women newly diagnosed with CRC with 22 cancer-free women matched on age, BMI, and race in a 1:2 ratio was conducted. Information about participants’ diet and perceived stress levels were obtained via 24-hour Dietary Recall and Perceived Stress Scale-10 survey, respectively. Participants provided stool samples from which microbial genomic DNA was extracted to reveal the abundance of 26 genera chosen a priori based on their previously observed relevance to CRC, anxiety symptoms, and diet.
Results
Significantly lower alpha diversity was observed among cancer-free Black women compared to all other race-cancer status combinations. No group differences were observed when comparing beta diversity. Non-Hispanic White CRC cases tended to have higher relative abundance of Fusobacteria, Gemellaceae, and Peptostreptococcus compared to all other race-cancer combination groups. Perceived stress was inversely associated with alpha diversity and was associated with additional genera.
Conclusions
Our findings suggest that microbiome-CRC associations may differ by racial group. Additional large, racially diverse population-based studies are needed to determine if previously identified associations between characteristics of the gut microbiome and CRC are generalizable to Black women and other racial, ethnic, and gender groups.
Exploring the Mechanism of Action of Lobetyolin in the Treatment of Allergic Rhinitis based on Network Pharmacology and Molecular Docking
Authors: Hou Li , Yang Jing , Li YanRong , Kang Jing , Ma Zheng , Luo XiaoYa , Yang XiaoLing , Shao Hui 
Published: January 2023

Abstract
Lobetyolin (LBT) is an important active ingredient in the traditional medicinal plant Codonopsis pilosula (Franch.) Nannf. However, the pharmacological targets and mechanisms of action of LBT against allergic rhinitis (AR) are not known. The aim of this study was to evaluate the possible functional role and potential mechanism of LBT as an anti-AR treatment through a combination of network pharmacology and molecular docking. The disease database and target screening database were used to find potential targets for screening LBT for the treatment of AR. Further network visualization analysis, gene ontology (GO) enrichment analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis were performed for potential targets. Finally, we performed some molecular docking with LBT and core targets to verify their relevant effects. The results revealed that a total of 64 target genes were obtained for LBT for AR. The top 10 targets with the highest enrichment scores were TNF, EGFR, MMP9, TLR4, ERBB2, JUN, CXCR4, HSP90AA1, KDR, and MMP2. GO and KEGG enrichment analysis showed that multiple signaling pathways are involved in LBT for AR. Molecular docking results showed that LBT binds strongly to the target proteins MMP2, MMP9, TNF, JUN, and EGFR through intermolecular forces. This study reveals for the first time the pharmacological targets and related pathways of LBT for the treatment of AR, indicating that LBT can intervene in the intrinsic molecular mechanism of AR through multiple targets and pathways.