bluuebunny/crossref_metadata_2025_split huggingface dataset:
Network intrusion detection based on multi-domain data and ensemble-bidirectional LSTM
Authors: Wang Xiaoning , Liu Jia , Zhang Chunjiong 
Published: June 2023

AbstractDifferent types of network traffic can be treated as data originating from different domains with the same objectives of problem-solving. Previous work utilizing multi-domain machine learning has primarily assumed that data in different domains have the same distribution, which fails to effectively address the domain offset problem and may not achieve excellent performance in every domain. To address these limitations, this study proposes an attention-based bidirectional long short-term memory (Bi-LSTM) model for detecting coordinated network attacks, such as malware detection, VPN encapsulation recognition, and Trojan horse classification. To begin, HTTP traffic is modeled as a series of natural language sequences, where each request follows strict structural standards and language logic. The Bi-LSTM model is designed within the framework of multi-domain machine learning technologies to recognize anomalies of network attacks from different domains. Experiments on real HTTP traffic data sets demonstrate that the proposed model has good performance in detecting abnormal network traffic and exhibits strong generalization ability, enabling it to effectively detect different network attacks simultaneously.
SipNose-topiramate: a potential novel approach to binge eating management
Authors: Kobo-Greenhut Ayala , Zohar-Beja Adit , Hadar Liron , Itzhaki Lior , Karasik Avraham , Caraco Yoseph , Frankenthal Hilel , Shahaf Daniel , Ekstein Dana , Shichor Iris , Gur Eitan 
Published: June 2023

Abstract
Background
Binge-eating disorder) BED) is the most common eating disorder in the United-States. Daily, orally administered topiramate has shown BED treatment efficacy, with two major limitations: frequent and severe side effects and slow time-to-effect. SipNose is a novel non-invasive intranasal direct nose-to-brain drug delivery platform that delivers drugs to the central nervous system consistently and rapidly. Herein, we study a SipNose-topiramate combination product, as an acute “as needed” (PRN) solution for BED management.

Methods
First, SipNose-topiramate’s pharmacokinetics (PK) and safety was evaluated. The second part aimed to demonstrate its PRN-treatment feasibility in terms of usability and potential efficacy in reducing the number of binge-eating events. Twelve BED patients were studied over three time periods; 2-weeks of baseline monitoring [BL], 8-weeks of treatment [TX], and 2-weeks of follow up [FU].

Results
The PK profile showed peak plasma levels at 90 min post-administration, a t1/2 > 24 h and consistent topiramate delivery with no adverse events. In the second part, 251 treatments were self-administered by the patient participants. There was a significant reduction from baseline to treatment periods in mean weekly binge-eating events and binge-eating event days per week. This was maintained during the follow up period. Efficacy was corroborated by improved patient illness severity scales. There were no adverse events associated with any administered treatments. Patients were exposed to less drug when compared with accepted oral dosing.

Conclusions
This study introduces a SipNose-topiramate drug-device combination as a potentially safe, effective, and controlled method for BED management. Its findings introduce a potential approach to BED management both as an intranasal and as a PRN therapy for reducing binge-eating events, with a large-scale reduction in patient drug exposure and side effects and with improved patient quality of life. Further studies are needed with larger patient populations to establish SipNose-topiramate as a mainstream treatment for BED.
Trial registration: Registration number and date of registration of the clinical studies reported in this article are as follows: 0157-18-HMO, August 15th 2018 and 6814-20-SMC, December 2nd 2020.
Ultrafine and crosstalk-free 2D tactile sensor by using active-matrix thin-film transistor array
Authors: Kinjo Hiroumi , Tanaka Hitoshi , Haga Yuta , Tamaru Takaya , Kobashi Junji , Sako Kazuhiko , Yamaguchi Kazunori , Oka Shinichiro 
Published: June 2023

AbstractPassive matrix (PM) technologies are widely used in various fields (e.g., manufacturing, human sensing, and robotics) to visualize the tactile pressure distribution. These technologies are powerful addressing methods with simple structures, low cost, and easy fabrication steps. However, crosstalk problems have been pointed out, especially in high-resolution fields. To prevent a crosstalk occurrence, we adapt active-matrix (AM) technologies for ultrafine tactile imaging. In this work, two-dimensional (2D) tactile sensors are prepared using AM arrays fabricated through standard display processes. Pressure-sensitive resistor sheets are then attached. The sensors have 6720 px in a 90 × 90 mm sensing area with a 1.1 mm pixel pitch. The crosstalk is evaluated by pressurizing the control area of the sensor and measuring the output in the non-pressurized area. No pixel is affected by the pressure outside the pixel itself, or no crosstalk occurs. For a demonstration, static pressure from soft toy balls and dynamic foot pressure during walking are loaded to the 2D tactile sensors. The differences in the contact mode by the ball type and the pressure of each finger are observed, thanks to the 1.1 mm-pitch without crosstalk. The 2D tactile sensors presented herein will contribute to the fundamental understanding of the contact interface and will have practical usage in sport sciences, biometric identifications, and tactile sensation of robots.
Outcome of extradural devascularization in resection of giant olfactory groove meningioma in bilateral subfrontal approach
Authors: Elsisi Yasser Bahgat , Hossen Mohamed Adel , Al Emam Saeed Esmaeel 
Published: June 2023

Abstract
Background
Olfactory groove meningioma (OGM) is characterized by slow-growing tumors that are frequently bilateral as opposed to unilateral & asymmetrical and may cause progressive frontal lobe compression. We aimed to evaluate the value of extradural devascularization as a golden step in bilateral subfrontal approach in management of OGM.

Results
The mean operative time was 158.32 ± 24.88. Blood loss ranged from 500 to 1000 cc with a mean value of 763.64 ± 155.98. The number of patients requiring blood transfusion was 5 (22.7%). Based on Simpson classification, 19 (86.4%) patients had whole tumor excision (grade I, II) & 3 (13.6%) patients had grade III and IV. The incidence of complications among the studied patients is: CSF leak did not occur to any case, pneumocephalus occurred in 1 (4.5%) patient, anosmia occurred in 1 (4.5%) patient, focal CNS deficit occurred in 1 (4.5%) patient, wound infection occurred in 1 (4.5%) patient and hematoma occurred in 1 (4.5%) patient. Only 1 (4.5%) case died due to pulmonary embolism, whereas behavioral manifestations occurred in 9.09% of patients.

Conclusions
The extradural devascularization is a golden step in this approach in management of OGM associated with lower incidence of blood loss intraoperatively (total blood loss was 500–1000 mL, recurrence rate, mortality and additional neurological deficits postoperatively.
A retrospective study comparing open and percutaneous trigger finger release in the Thai population
Authors: Malisorn Saran 
Published: June 2023

Background: Over the years, open surgery has been the primary treatment for trigger finger, a prevalent issue among hand illnesses. There has been some resistance to the technique's routine use, despite the fact that the percutaneous release of triggers provides a quicker recovery than surgery. As a result, the study proposed that the percutaneous release technique outperforms open surgery. The objective of this study was to compares the trigger finger surgery's open and percutaneous releases in terms of short-term results. Methods: From 2014 to 2020, 166 patients who underwent open or percutaneous release surgery for the trigger finger at Naresuan University Hospital were the subjects of this retrospective analysis. For one, three, and six weeks, the initial characteristics and post-operative hemorrhage, digital nerve and artery injury, surgical site pain, inability to flex the finger, and other outcomes were compared. The visual analog scale (VAS) score and the impairments of the arm, shoulder, and hand (DASH) score were also compared between the two groups. Results: The age, sex, and number of patients in both groups were statistically comparable. Before the procedure, there was no difference between the groups in terms of DASH and VAS scores for pain; however, at six weeks, the percutaneous release group showed a substantial difference and low VAS scores. There were no differences between the groups in terms of consequences, including wound pain, damage to digital nerves and arteries, and others. Conclusion: Based on the patients' short-term outcomes, the study found that percutaneous release of the trigger finger is just as successful as traditional open surgery.
Synchronous borderline ovarian tumor with endometrioid endometrial carcinoma - from diagnosis to treatment. A Case study
Authors: Kolasa Eliza , Paluch Alicja , Satora Małgorzata , Kułak Krzysztof 
Published: June 2023

Introduction
The occurrence of two primary tumors at an interval of no more than two months is called a synchronous tumor. This also applies to female reproductive organs among which synchronous occurrence of ovarian and endometrial cancers is most frequently observed. This phenomenon is observed mainly in young women before menopause. A rare and problematic diagnostic situation is the synchronous co-occurrence of borderline ovarian carcinoma with endometrioid carcinoma of the endometrium. The diagnostic problem and treatment of this combination of cancers are presented in the following case.
Case description:
A 30-year-old female patient presented to the Gynecologic Oncology Department with a suspected malignant lesions of both ovaries. She underwent fertility-sparing surgery with preservation of the left ovary and uterus. Examination of the resected tissues revealed an endometrioid borderline tumor. During the next hospitalization, an excision of uterine polyps was performed, during which no neoplastic lesion of the endometrium was observed. Ultrasound examination, in which the endometrial lesion was also invisible, raised suspicion of cancer recurrence on the left ovary. The patient was scheduled for resection of the left ovary with the recurrence and hysterectomy. The histopathological examination performed confirmed the recurrence on the ovary and showed foci of G1 endometrioid carcinoma of the uterus.
Conclusions
Cases that meet the criteria for synchronous tumor occurrence should be considered. Appropriate diagnosis and selection of radical treatment could affect the curability of patients. Further research on rare combinations of synchronous neoplasms could be helpful in clinical practice.
Black pearls in Little Africa
Authors: Furtado Junia 
Published: June 2023

The village of Tejuco, now the town of Diamantina, was the center of the Diamond District in the Northeast of the captaincy of Minas Gerais. The aim of this article is to unveil, using a census and a map from around 1774, some of the layers of the feminine geography of the social life of the village. This reveals a more dynamic and plural configuration of Tejuco, where a significant number of people of color, mostly black African women, were heads of household. Their presence transformed Tejuco into a Little Africa.
HOW INTERNATIONAL STANDARDS OF WOMEN'S RIGHTS WERE BORN: THE EXPERIENCE OF ANALYZING THE LEGAL POLICY OF THE UNITED NATIONS IN THE 1950–1970S.
Authors: Головинов А.В. , Golovinov Yu.V. 
Published: June 2023

The purpose of the article is to show the history of the formation of the legal foundations of genderequality in the rule-making activities of the United Nations in the period of 1950–1970s. The chronologicalframework was not chosen by chance, it was for the 50–70s. 20th century there was an active phase of the adoption of legal contractual documents in the field of the institution of the rights of women and men. Theauthors analyze the consistent history of the UN legal policy in this area.The article establishes that a decisive struggle against gender asymmetry fell on the initial stage of theformation of an organization that aims at world peace. In general, the authors come to the conclusion thatfrom the second half of the XX century. in the world community, the process of developing internationallegal acts in the field of protecting women's rights has been developed. Progress in defining the essence andcontent of women's rights proceeded naturally and evolutionarily. International conventions and pacts inthis area were progressively adopted. Ultimately, women were equalized with men. Anti-discriminationinternational legislation was actively developed.
The European Parliament’s AI Regulation
Authors: Haataja Meeri , Bryson Joanna J. 
Published: June 2023

The European Union (EU) has been leading the world with its influential digital regulation. However, the EU’s legislative process is sufficiently complex and careful that some national legislation clearly influenced by the EU’s AI Regulation is already in place in other countries, before the law has even been finalized in the EU. Meanwhile, other states and regions are just beginning to develop AI policy. For both the EU and such others, we here describe the outcomes of the first round of legislative action by one of the EU’s two legislative bodies, the European Parliament, in terms of modifying the Artificial Intelligence Act. The Parliament has introduced a number of changes we consider to be enormously important, some in a very good way, and some in a very bad way. At stake is whether the AI Act really brings the power and strength of product law to continuously scale improved practice on products in the EU with intelligent components, or whether the law becomes window-dressing aimed only at attacking a few elite actors post hoc. We describe here the EU process, the changes and our recommendations.
Keywords: AI Act; digital governance; AI regulation; parliamentary processes; European Union; transnational regulation.
A British Bundesrat? The Brown Commission and the Future of the House of Lords
Authors: Meggitt Gary 
Published: June 2023

Reform of the House of Lords has occupied the minds of politicians, civil servants and academics for over a century. In late 2022, the Labour Party published a proposal for the replacement of the Lords with a new, democratically elected, Assembly of the Nations and Regions. This proposed Assembly resembles, at least superficially, the German Bundesrat. The author reviews the history of Lords reform, examines Labour’s proposals, compares the envisioned Assembly with the Bundesrat and concludes that the former will be found wanting.
Keywords: United Kingdom; Germany; constitutional law; Parliament; House of Lords; Bundesrat; constitutional reform.
Tikanga and the Law
Authors: Whata Justice Christian 
Published: June 2023

This paper is based on the transcript from a presentation given at the New Zealand Asian Lawyers Wānanga on Tikanga and the Law given on 3 May 2023. This paper offers one of many explanations of tikanga and is an entry level introduction only to a complex kaupapa. This paper traverses briefly a proposed three-part model of recognition of tikanga. The first part of the model is a methodology of engagement. The second part is the notion of kaitiaki as a controlling principle. The third part is tikanga-enabling processes. The last two steps of the methodology are covered briefly due to time restraints.
Keywords: tikanga; normative system; recognition; methodology of engagement; tikanga-enabling processes; common law.
Summary Dismissal in Arbitration
Authors: Marsden Oliver , Kelly Joshua , Everett Caspar 
Published: June 2023

This article considers the United Kingdom Law Commission’s recent proposal to amend the Arbitration Act 1996 so as to expressly empower arbitral tribunals to make orders for summary dismissal of meritless claims/defences (among several other reforms to the Act). Noting the summary dismissal procedures available in the English courts and the provisions for summary dismissal now included in the procedural rules of the major arbitral institutions, this article concludes that such an amendment to the 1996 Act would be a very welcome development, promoting efficiency in London-seated arbitration and thereby further securing London’s position as one of the most popular seats of arbitration.
Keywords: summary dismissal; summary judgment; Arbitration Act 1996.
Is Legal Knowledge Regressing (Thanks to AI)?
Authors: Samuel Geoffrey 
Published: June 2023

This review article focuses on a recent book that poses the following question. Is law computable? In examining some of the contributions in this edited collection the article poses a second question. Is, as a result of artificial intelligence (AI) and law research, legal knowledge regressing? In its analysis of the book, the article examines several of the major epistemological problems facing the creators of a legal reasoning AI programme; and it concludes that some of the epistemological assumptions upon which AI research is based are assumptions rooted in old and discredited legal knowledge. Nevertheless, the article has few illusions that judging will one day be dispensed by robot judges, especially if liberal democratic cultures slide slowly into authoritarian societies.
Keywords: artificial intelligence; computer; Deakin (Simon); epistemology; Markou (Christopher); mos mathematicus; reasoning (legal); rule-model.
Phytochemical, Antimicrobial and Cytotoxic Activities of Strophanthus sarmentosus DC
Authors: Abiola Julius Leke , Aiyelaagbe Olapeju Oluyemisi 
Published: June 2023

Strophanthus sarmentosus DC is used traditionally in the management of snake-bite, arthritis, eye infection, rheumatism, emetic and venereal diseases. Freshly collected mature Strophanthus sarmentosus plant parts were air-dried at room temperature. Each of the plant parts (leaf, stem and roots) was successively extracted by cold extraction method using hexane, ethyl acetate and methanol respectively. The crude extracts were subjected to phytochemical, antimicrobial and cytotoxicity analysis by employing chemical tests, agar diffusion and brine shrimps methods.The phytochemical screening showed the presence of tannins, saponins, glycosides, flavonoids, phenols, steroids, terpenoids and carbohydrates in all the extracts. The extracts demonstrated broad spectrum activities against both gram- positive and gram-negative bacteria and the fungi tested. The MIC and MMC of ethyl acetate and methanol extracts of the S. sarmentosus (stem) is between 0.3 and 5.0 mg/mL. The cytotoxic activity (LC50) of the S. sarmentosus extracts (leaf, stem and root) ranged between 117 µg/mL and 270 µg/mL, showing that the extracts are within the medium toxic level according to Clarkson’s toxicity index.
Peran Mediasi Network Heterogeneity pada Hubungan Online Subjective Well-Being dan Social Media Fatigue pada Pengguna Media Sosial
Authors: Prabowo Adhyatman 
Published: June 2023

The use of social media has many implications for individuals. One of the impacts that arises is users’ Online Subjective Well-Being (OSWB). This study aims to explore the relationship between OSWB and Social Media Fatigue (SMF) mediated by network heterogeneity; privacy concern, social comparison and selfdisclosure. This correlational research design used early adult respondents of a range of ages 20 - 30 years (N = 337) which was taken using non-probability quota sampling. Data was analyzed using SPSS Process (Model 4) by Hayes. The results showed that OSWB was able to predict SMF directly. The factors which succeed in mediating OSWB and SMF were self-disclosure, while privacy concerns and social comparison were unable to act as mediator. However, all three mediating variables have a positive correlation with SMF. Individuals with high OSWB are predicted to have lower SMF. In addition, the role of self-disclosure greatly determines the occurrence of SMF. Penggunaan media sosial membawa banyak implikasi bagi individu. Salah satu dampak yang muncul adalah Online Subjective Well-Being (OSWB) pengguna. Penelitian ini bertujuan untuk mengeksplorasi hubungan antara OSWB dan Social Media Fatigue (SMF) yang dimediasi oleh network heterogeneity; privacy concren, social comparison dan self-disclosure. Penelitian koreasional ini melibatkan responden dewasa awal dengan rentang usia 20 - 30 tahun (N = 337) dengan pengambilan sampling menggunakan non probability quota sampling. Analisis data melalui SPSS Process (Model 4) oleh Hayes. Hasil penelitian menujukkan OSWB mampu memprediksi SMF secara langsung. Adapun faktor yang berhasil menjadi mediasi adalah self-disclosure sedangkan privacy concerns dan social comparison tidak mampu menjadi mediator. Namun demikian, ketiga variabel mediasi berkorelasi positif dengan SMF. Individu dengan OSWB yang tinggi diprediksi memiliki SMF yang lebih rendah. Selain itu, peran self-disclosure dalam diri sangat menentukan proses terjadinya SMF.
Studi Meta-analisis: Welas Diri dan Kecemasan
Authors: Polii Clarissa Firanda , Yudiarso Ananta 
Published: June 2023

Anxiety is defined as a physiological response to the possibility of problems arising in individuals. Anxiety is known to have a relationship with other variables, one of which is self-compassion. Individual self-compassion will be able to influence the level of anxiety. Individuals who have self-compassion will tend to avoid negative emotions that cause anxiety. This meta-analytic study aims to look at the relationship between anxiety and self-compassion in the last five years of research from 2018 to 2023 with a total of 10,489 respondents. The results of the study found that self-compassion had a moderate effect size (-0.55) with heterogeneity (I 2 ) of more than 88.81%, so this study used a random effects size. Therefore, self-compassion is interpreted as having a moderate effect that is negatively correlated with levels of anxiety. Kecemasan didefinisikan sebagai respon secara fisiologis dari kemungkinan munculnya permasalahan pada individu. Kecemasan diketahui memiliki kaitan dengan variabel lain salah satunya welas diri. Welas diri yang dimiliki individu akan mampu mempengaruhi tingkat kecemasan. Individu yang memiliki welas diri akan cenderung terhindar dari emosi negatif yang menyebabkan kecemasan. Studi meta-analisis ini bertujuan untuk melihat hubungan antara kecemasan dan welas diri dalam penelitian lima tahun terakhir dari tahun 2018 hingga 2023 dengan total responden sebanyak 10.489 orang. Hasil penelitian menemukan bahwa welas diri memiliki medium effect size (-0,55) dengan heterogenitas (I 2 ) lebih dari 88,81%, sehingga penelitian ini menggunakan random effects size. Oleh karena itu, welas diri diartikan memiliki efek sedang yang berkorelasi secara negatif pada tingkat kecemasan.