bluuebunny/crossref_metadata_2025_split huggingface dataset:
Antiobesity effects of onion (Allium cepa) in subjects with obesity: Systematic review and meta‐analysis
Authors: Chung Min‐Yu , Hwang Jin‐Taek , Park Soo‐Hyun 
Published: May 2023

AbstractOnions are rich in bioactive compounds and have been found to prevent various chronic diseases, including obesity. We performed a systematic review and meta‐analysis to investigate the antiobesity effect of onions. Studies were identified in PubMed/MEDLINE, Embase, Web of Science, and CENTRAL focusing on clinical trials evaluating the antiobesity effects of onion in obese subjects. The risk of bias in the studies was evaluated using Cochrane's Risk of Bias tool. The effect of onions was analyzed using data from the selected studies, and the results were indicated by weighted mean difference with 95% CI. The I2 static test was used to examine heterogeneity between the studies. A total of 38 studies were reviewed, of which five clinical trials meeting the criteria were selected. As investigational products, onion peels were used in four studies and onions were used in one study. Following systematic review, it was determined that the risk of bias was generally low, and body weight, BMI, waist circumference, and triglyceride levels were significantly reduced in the onion groups compared to the placebo. In conclusion, onion intake had an antiobesity effect by reducing body weight and body fat, and this effect was particularly pronounced with onion peel.
Significant heterogeneity in structural asymmetry of the habenula in the human brain: A systematic review and meta‐analysis
Authors: Abuduaini Yilamujiang , Pu Yi , Thompson Paul M. , Kong Xiang‐Zhen 
Published: May 2023

AbstractUnderstanding the evolutionarily conserved feature of functional laterality in the habenula has been attracting attention due to its potential role in human cognition and neuropsychiatric disorders. Deciphering the structure of the human habenula remains to be challenging, which resulted in inconsistent findings for brain disorders. Here, we present a large‐scale meta‐analysis of the left–right differences in the habenular volume in the human brain to provide a clearer picture of the habenular asymmetry. We searched PubMed, Web of Science, and Google Scholar for articles that reported volume data of the bilateral habenula in the human brain, and assessed the left–right differences. We also assessed the potential effects of several moderating variables including the mean age of the participants, magnetic field strengths of the scanners and different disorders by using meta‐regression and subgroup analysis. In total 52 datasets (N = 1427) were identified and showed significant heterogeneity in the left–right differences and the unilateral volume per se. Moderator analyses suggested that such heterogeneity was mainly due to different MRI scanners and segmentation approaches used. While inversed asymmetry patterns were suggested in patients with depression (leftward) and schizophrenia (rightward), no significant disorder‐related differences relative to healthy controls were found in either the left–right asymmetry or the unilateral volume. This study provides useful data for future studies of brain imaging and methodological developments related to precision habenula measurements, and also helps to further understand potential roles of the habenula in various disorders.
Identification of behavioural changes in reporting adverse events early during COVID‐19: An ambulatory care perspective in Israel
Authors: Reychav Iris , Yaakobi Alon , McHaney Roger , Tal Yossi , Manor Orly 
Published: May 2023

AbstractThis study examined adverse event reporting centred on three significant dates in the months before the pandemic arrived in Israel. On these dates, broad media coverage exposed citizens and health care providers with indications about the forthcoming pandemic. The current study tracked whether parameters related to reporting adverse medical events provided early indications that a large crisis was unfolding. The method for analysing the data was based on a statistical test called Regression Discontinuity Design, which helped identify parameters related to medical reporting patterns which significantly changed. The examination indicated nurses' reports were unique in relation to others and indicated three phases: (1) upon declaration of the upcoming pandemic, there was a rise in reporting; (2) when the disease was named, there was moderation and maintenance in a steady quantity of reports, and finally, (3) when the first case arrived in Israel, a slight decrease in reporting began. Nurses' behaviours manifested as changes in reporting patterns. In this process of increase, moderation and decrease, it can be concluded that these are three stages that may characterise the beginning of a large event. The research method presented reinforces the need for forming tools by which significant events such as the COVID‐19 pandemic can be identified quickly, and aid in proper planning of resources, optimise staffing and maximise utilization of the health systems.
COVID‐19 vaccination success in Bangladesh: Key strategies were prompt response, early drives for vaccines, and effective awareness campaigns
Authors: Nazmunnahar  , Ahamed Bulbul , Haque Md. Anamul , Tanbir Md. , Roknuzzaman A. S. M. , Sarker Rapty , Rabiul Islam Md. 
Published: May 2023

AbstractBangladesh is located in Southeast Asia that has a high population density. It is a lower‐middle‐income country. The COVID‐19 pandemic severely impacted the nation that slowed its economic growth. It halted major industries, crippling the nation's economy. The students were uncertain after the declaration of school closures. Hospitals could not treat other patients properly due to the vast health burden of COVID‐19. Bangladesh put up a solid fight during COVID‐19 as a lower‐middle‐income country. Prompt action, early vaccination drives, effective awareness campaigns, and widespread public involvement have enabled Bangladesh to bring more than 90% of its population into COVID‐19 vaccination coverage. It was possible by the effective diplomatic and local health strategy implemented by the Bangladeshi government, the country's extensive prior experience, and its long history of achieving a high success rate in other vaccination campaigns. Bangladesh was able to flatten the curve sooner than other developed countries. Therefore, the cogs of everyday social life and the economy begin to turn once more. The strategy Bangladesh used to combat the COVID‐19 pandemic through vaccination and diplomatic policy by calling on its prior experience has the potential to serve as a model for other low‐ and middle‐income countries and an example for developed nations.
Mother–child separation after twin birth in a maternity unit with an appropriate level of neonatal care
Authors: Pauphilet Victoire , Goffinet François , Korb Diane , Zeitlin Jennifer , Torchin Heloïse , Schmitz Thomas ,   for the Jumeaux Mode d'Accouchement (JUMODA) study group and the Groupe de Recherche en Obstétrique et Gynécologie (GROG)
Published: May 2023

AbstractObjectiveTo evaluate the mother–child separation rate in twin pregnancies delivered in maternity units offering an appropriate level of neonatal care.MethodsJUMODA is a French, prospective, population‐based cohort study of twin deliveries, including 7998 women who gave birth in maternity units with appropriate levels of neonatal care based on thresholds for weeks of gestational age (wGA) and birth weight according to French guidelines: level I (≥36 wGA), IIA (≥34 wGA), IIB (≥32 wGA and ≥ 1500 g), and IIII (<32 wGA or < 1500 g). The primary outcome was mother–child separation, defined as the transfer of at least one twin or the mother to another hospital.ResultsMother–child separation occurred in 2.1% of pregnancies. This rate was significantly higher in level I (4.8%, 95% confidence interval [CI] 1.5–12.5) and IIA (3.4%, 95% CI 2.4–4.7) compared with level IIB (1.6%, 95% CI 1.1–2.3) and level III maternity units (2.1%, 95% CI 1.9–2.8). In level IIA units, the rate of mother–child separation was higher for babies born between 34 and 36 wGA (8.3%) than for those born at 36 wGA or beyond (1.7%). In level IIb, the rate of mother–child separation for babies born between 32 and 34 wGA (7.5%) was higher than for those born between 34 and 36 wGA (2.1%) and at 36 wGA or beyond (0.9%).ConclusionMother–child separation rates were low but differed by level of care. By using specific thresholds for twins to define levels of care, rather than data from singleton births, one‐fifth of mother–child separations could have been avoided.
Comparison of an automated digital cell morphology analysis system with manual counting
Authors: Jiao Juan , Yin Xin , Ma Jiali , Xia Yinglong , Xu Jianxia , Zhao Shaozhe , Liu Jie 
Published: May 2023

AbstractBackgroundBionovation's CSFA800 is a new automated digital cell imaging analyzer. We evaluated the performance of the CSFA800 by comparing it with artificial peripheral blood white blood cell counting.MethodsAccording to inclusion and exclusion criteria, 131 randomly selected samples (77 abnormal samples and 54 normal samples) were compared. Correlations between automated and manual counting results were analyzed. Manual counting was carried out according to the guidelines of the Association of Clinical and Laboratory Standards.ResultsCounts of neutrophils, lymphocytes, monocytes, eosinophils, basophils, and immature granulocytes obtained from CSFA800 and artificial methods were linearly and positively correlated, with R values of 0.73, 0.65, 0.24, 0.2, 0.4, and 0.63, respectively, all p < 0.05. Therefore, correlations between CSFA800 and manual counting are acceptable. Compared with the DI‐60 Automated Digital Cell Morphology System (DI‐60; Sysmex), CSFA800 is more efficient and can analyze 20,000 cells in 1 min. However, the overall accuracy of CSFA800 is not as good as DI‐60, although its counting performance is better for basophils.ConclusionsThe performance of CSFA800 for WBC counts is acceptable, and it displayed good performance for neutrophils, lymphocytes, and immature granulocytes. Compared to DI‐60, CSFA800 is more efficient but has slightly lower overall accuracy. To some extent, CSFA800 is helpful to optimize the clinical laboratory workflow and improve the working efficiency of inspectors.
Comparison of adsorption performance for Cd(II) removal from aqueous solution using biochar derived from different types of carbon sources: aquatic plants, pine branches and peat
Authors: Li Yuhuan , Sui Xin , Wang Xuemei , Ji Hongbing 
Published: May 2023

AbstractBACKGROUNDGuizhou Province, China is rich in forest, peat and aquatic plants. The effect of biochar prepared by pyrolysis carbonization on the Cd(II) adsorption has not been effectively studied. In this work, the physicochemical structural characteristics of different biochars were investigated. On this basis, the influence of pH value, acid washing, adsorption time on Cd(II) removal efficiency and the characteristics of adsorption isotherms of four biochars were studied. The adsorption mechanism was discussed by adopting the Langmuir and Freundlich kinetic model.RESULTSThe findings exhibited that PT contained a great amount of free humic acid, fulvic acid and montan wax, which had a considerable impact on the Cd(II) adsorption. The surface of biochar AP300 has a fine crack structure, and the specific surface area (SSA) is the largest, reaching 2.9006 m2/g. When the solution range in pH value above 6, the removal efficiency of PT and biochar AP300 for Cd(II) exceeds 80%. The acid‐washed biochar with increased SSA did not exhibit an increase in Cd(II) removal efficiency, or even decreased significantly. Under the same adsorption time, the Cd(II) removal efficiency was in the following order: PT>AP300>PT300>PB300. The fitting effect of the Freundlich model for the four biochars was more than a match for Langmuir model, and the former is more appropriate to expression of the adsorption mechanism of Cd(II). Among the four biochars, AP300 had the smallest ΔG°, and the Cd(II) adsorption was the most easily performed.CONCLUSIONBoth PT and AP carbon material adsorbents can both meet the removal of Cd (II) in water, and can be promoted to treat heavy metals in soil later. © 2023 Society of Chemical Industry (SCI).
Uptake of genetic testing among patients seeking cancer genetic counseling in Taiwan
Authors: Fang Su‐Ying , Hsieh Ling‐Ling , Hung Chen‐Fang , Wang Yong Alison 
Published: May 2023

AbstractGenetic testing is becoming increasingly available and affordable. Understanding the reasons for individual decisions about genetic testing may assist in the identification of clinically appropriate use of genetic counseling and genetic testing resources. With the ongoing development of cancer genetic counseling services in Taiwan, we conducted this study to understand the characteristics of those seeking cancer genetic counseling and genetic testing and the predictors for undergoing genetic testing after counseling. Cross‐sectional with correlational design was used in this study. Surveys completed by patients visiting the genetic counseling clinic at the cancer center included demographics, personal and family history of cancer, and questions on attitudes toward genetic counseling and genetic testing. Multinomial logistic regression was used to analyze the predictors of decision to undergo genetic testing. A total of 120 participants between the years 2018 and 2021 were analyzed, of which 54.2% were referred by health care professionals. The majority (76.7%) had a personal history of cancer and 50% had breast cancer. Over half (53.3%) had a strong family history of cancer defined as two or more 1st‐degree relatives having cancer at a young age. Only 35.8% decided to receive genetic testing right after counseling and 47.5% were undecided. The main reason for hesitation or not pursuing testing was cost (41.4%). Multivariate logistic regression analysis showed that a positive attitude toward genetic counseling was significantly associated with the uptake of genetic testing (Odds ratio 7.60, 95% CI 2.34–24.66, p < 0.001). Given the significant number of individuals undecided about genetic testing after counseling, decision aid could be developed to support genetic counseling and increase satisfaction with the testing decision.
Application of near‐infrared spectroscopy for the estimation of volatile compounds in Tempranillo Blanco grape berries during ripening
Authors: Marín‐San Román Sandra , Fernández‐Novales Juan , Cebrián‐Tarancón Cristina , Sánchez‐Gómez Rosario , Diago María Paz , Garde‐Cerdán Teresa 
Published: May 2023

AbstractBACKGROUNDThe knowledge of volatile compounds concentration in grape berries is very valuable information for the winemaker, since these compounds are strongly involved in the final wine quality, and in consumer acceptance. In addition, it would allow to set the harvest date according to aromatic maturity, to classify grape berries according to their quality and to make wines with different characteristics, among other implications. However, so far, there are no tools that allow the volatile composition to be measured directly on intact berries, either in the vineyard or in the winery.RESULTSIn this work, the use of near‐infrared (NIR) spectroscopy to estimate the aromatic composition and total soluble solids (TSS) of Tempranillo Blanco grape berries during ripening was evaluated. For this purpose, the spectra in the NIR range (1100–2100 nm) of 240 intact berry samples were acquired in the laboratory. From these same samples, the concentration of volatile compounds was analyzed by thin film‐solid‐phase microextraction‐gas chromatography–mass spectrometry (TF‐SPME‐GC–MS), and the TSS were quantified by refractometry. These two methods were used as reference methods for model building. Calibration, cross‐validation and prediction models were built from spectral data using partial least squares (PLS). Determination coefficients of cross‐validation (R2CV) above 0.5 were obtained for all volatile compounds, their families, and TSS.CONCLUSIONSThese findings support that NIR spectroscopy can be successfully use to estimate the aromatic composition as well as the TSS of intact Tempranillo Blanco berries in a non‐destructive, fast, and contactless form, allowing simultaneous determination of technological and aromatic maturities. © 2023 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Effects of different colors of film mulch on soil temperature and rice growth in a non‐flooded condition
Authors: Zhang Youliang , Huang Chenyu , Zhao Long , Feng Shaoyuan , Zhao Zhonghua , Zhang Lu 
Published: May 2023

AbstractBACKGROUNDRice cultivation under film mulching with no flooding is widely used as an effective water‐saving technology. Different colors of film mulch have different effects on the soil hydrothermal environment and crop growth because of their different optical properties. However, the effects of different colors of film mulch on soil temperature and rice physiological growth are not clearly understood.RESULTSField experiments were conducted in 2019 and 2020 to investigate the effects of different color mulches on soil temperature and rice growth in a non‐flooded condition. Transparent film (TM), black film (BM), two‐color film (BWM, silver on the front and black on the back), and no film (NM) in a non‐flooded condition were designed. Soil temperature variation at different soil depths of 0–0.25 m and rice plant height, stem thickness, dry matter, yield and quality were monitored. The results showed that compared to no mulching, the mulching treatment effectively increased the average soil temperature during the whole rice growth stage with the soil temperature ranked TM > BM > BWM. Compared with NM, the BM and BWM treatments increased rice yield by 12.1–17.7% and 6.4–14.4% in 2019 and 2020, respectively. The BWM had 18.2% and 6.8% greater gel consistency than NM in 2019 and 2020, respectively.CONCLUSIONTransparent film should be applied with care because of the high soil temperature stress. Black film and two‐color film (silver on the front and black on the back) could be better option for rice yield, increasing and quality improving in a non‐flooded condition. © 2023 Society of Chemical Industry.
Pilonidal sinus disease carcinoma: Survival and recurrence analysis
Authors: Safadi Mhd Firas , Degiannis Konstantinos , Doll Dietrich 
Published: May 2023

AbstractBackgroundThe study aims to determine the survival and recurrence rates of pilonidal sinus disease (PSD) carcinoma.MethodsThe data were collected retrospectively by searching the worldwide literature for all reports of carcinoma developing on the background of PSD. The results were presented using Kaplan–Meier curves.ResultsBetween 1900 and 2022, 140 cases of PSD carcinoma were published in 103 papers, with follow‐up data available in 111 cases. Squamous cell carcinoma constituted 94.6% of the cases (n = 105). The disease‐specific survival rate was 61.7% for 3 years, 59.8% for 5 years, and 53.2% for 10 years. There was a significant survival difference between stages: 80.0% in stages I and II, 70.8% in stage III, and 47.8% in stage IV (p = 0.01). The 5‐year survival in G1‐tumors was better than G2 and G3‐tumors at 70.5% and 32.0%, respectively (p = 0.002). Recurrence occurred in 46.6% of the patients. The time‐to‐recurrence in patients treated with curative intention averaged 15.1 months (1–132 months). Local, regional, and distant recurrence was observed in 75.6%, 33.3%, and 28.9% of the recurrent tumors, respectively.ConclusionsPilonidal sinus carcinoma has a worse prognosis than primary cutaneous squamous cell carcinoma. Poor prognostic factors include advanced‐stage disease and poor differentiation.
Reactive infectious mucocutaneous eruption secondary to SARS‐CoV‐2 and influenza A coinfection with varicella zoster virus reactivation
Authors: Moshayedi Aref , Malachowski Stephen J. , Haught Justin 
Published: May 2023

AbstractReactive infectious mucocutaneous eruption (RIME) is a newly proposed clinical entity characterised by post‐infectious mucositis involving two or more mucous membranes. The term expands the previously described Mycoplasma pneumoniae‐induced rash and mucositis to include additional infectious agents. We report a case of RIME secondary to SARS‐CoV2 and Influenza A coinfection with subsequent reactivation of varicella zoster virus on the lips. RIME can have significant clinical overlap with Stevens‐Johnson Syndrome and differentiation is key in limiting unnecessary future medication restrictions on patients. This report serves to increase awareness of RIME, including to coinfections and possible reactivation of Human Herpes Viruses.
Detecting Mild Phonotrauma in Daily Life
Authors: Van Stan Jarrad H. , Burns James , Hron Tiffiny , Zeitels Steven , Panuganti Bharat A. , Purnell Phillip R. , Mehta Daryush D. , Hillman Robert E. , Ghasemzadeh Hamzeh 
Published: May 2023

ObjectiveThe aim of this study was to gain quantitative insights into the role of daily voice use associated with mild phonotrauma via the Daily Phonotrauma Index (DPI), a measure derived from neck‐surface acceleration magnitude (NSAM) and difference between the first two harmonic magnitudes (H1 − H2).MethodsAn ambulatory voice monitor recorded weeklong voice use for 151 female patients with phonotraumatic vocal hyperfunction (PVH) and 181 female vocally healthy controls. Three laryngologists rated phonotrauma severity from each patient's laryngoscopy. Mixed generalized linear models evaluated the accuracy, sensitivity, and specificity of the original DPI trained on all patients versus a mild DPI version trained on only patients rated with mild phonotrauma. Individual contribution of NSAM and H1 − H2 to each DPI model was also evaluated.ResultsReliability across the laryngologists' phonotrauma ratings was moderate (Fleiss κ = 0.41). There were 70, 69, and 12 patients with mild, moderate, and severe phonotrauma, respectively. The mild DPI, compared to the original DPI, correctly classified more patients with mild phonotrauma (Cohen's d = 0.9) and less controls (d = −0.9) and did not change in overall accuracy. H1 − H2 contributed less to mild phonotrauma classification than NSAM for mild DPI.ConclusionsCompared with the original DPI, the mild DPI exhibited higher sensitivity to mild phonotrauma and lower specificity to controls, but the same overall classification accuracy. These results support the mild DPI as a promising detector of early phonotrauma and that NSAM may be associated with early phonotrauma, and H1 − H2 may be a biomarker associated with vocal fold vibration in the presence of lesions.Level of EvidenceLevel 4, case–control study Laryngoscope, 133:3094–3099, 2023