bluuebunny/crossref_metadata_2025_split huggingface dataset:
A First Report of Thyroid Pneumatosis as a Complication of Ultrasound-guided
Thyroid Biopsy
Authors: Li Honglu , Chen Wei , Xu Hua , Wang Chuanhong , Zou Huachun , Chen Yang , Lei Pinggui , Fan Bing 
Published: April 2023

Background:
Ultrasound-guided needle biopsies, including fine-needle aspirations (FNA) and core needle biopsies (CNB), have become an effective technique in the evaluation of thyroid nodules. In this report, we discuss the first reported case, to our knowledge, of thyroid pneumatosis after ultrasound-guided FNA.

Case Presentation:
A 44-year-old woman underwent ultrasound-guided FNA in other hospitals after thyroid ultrasound revealed a solid lesion in the left lobe classified as TI-RADS 4. Two days later, this female presented to our hospital for an excision of a thyroid mass. Pre- and post-contrast CT scans of the thyroid showed extensive accumulation of gas in the thyroid gland and the retropharyngeal and retrotracheal space. A CT scan of the thyroid two days later revealed obvious absorption of thyroid gas and faint low-density nodules in the left lobe of the thyroid. The lesion was histopathologically confirmed as papillary carcinoma of the thyroid.

Conclusion:
We thought the aforementioned issues originating from the limited imaging capacity of ultrasound in the context of thyroid biopsy. To avoid these limitations, we highlight the need to thoroughly examine the location of a lesion prior to thyroid biopsy to understand in detail the relationship between the lesion and the adjacent tissues, especially the proximity of the lesion to the trachea, the occurrence of coughing during a biopsy (indicating puncture of the trachea) is what operators need to be aware of so that they can manage such cases. On the other hand, we recommend that pre-operative use of CT before thyroid biopsy and especially if CT is needed anyway later for nodules evaluation before surgery to ensure the CT image quality.
A Conceptual Framework Towards the Realization of In situ Monitoring
and Control of End-to-End Additive Manufacturing Process
Authors: Karadgi Sachin , M. Bhovi Prabhakar , Patil Arun Y. , Ramaiah Keshavamurthy , Venkateswarlu K. , Langdon Terence G. 
Published: April 2023

Abstract:
Additive Manufacturing (AM) is considered one of the key technologies for realizing Industry
4.0. There are numerous stages in the end-to-end AM process, including component design, material
design, build, and so on. An enormous amount of data is generated along the end-to-end AM process
that can be acquired from the 3D printer in real-time, micro-characterization studies, and process
plan details, among others. For instance, these data can be employed to predict the printed components’
quality and, at the same time, proactively adapt the 3D printer parameters to achieve better quality.
This end-to-end AM process can be mapped onto the digital thread. The current article elaborates
on a conceptual framework to acquire the data from various sources associated with the end-to-end
AM process and realize monitoring and control of the end-to-end AM process, leading to an intelligent
AM process.
Chemical Detoxification of Therapeutic Hybrid Complexes Prepared by the
Compatible Combination of Ayurvedic Herb and Allopathic Drug
Authors: Bhawana Mishra , Deepak Pant , Suraj Gothwal , Akash Garhwal , Ramnarayan Yadav Sanjay , Ashok Nadda Kumar 
Published: April 2023

Background & Objective:
The treatment of diseases and good health maintenance are the common fundamental aims of ayurvedic and allopathic medical systems. Limited
information is available in the public domain for the concept of symbiohealth, i.e., the symbiotic interaction of ayurveda and allopathy, that needs
to be explored for an efficient and robust health system. Therefore, an attempt has been made to reduce the toxicity of therapeutic drugs via the
integration approach of ayurveda and allopathy.

Methods:
Three different categories of allopathy and ayurvedic medicines, such as antacids (omeprazole, ranitidine, and sooktybhasma), antibacterial
(amoxicillin trihydrate, ciprofloxacin hydrochloride, Curcuma longa, and Datura stramonium) and antiviral (acyclovir, efavirenz, Echinacea,
Calendula, Allium sativum, and Citrullus colocynthis) were targeted.

Results:
Best therapeutic hybrid combination was obtained on the basis of their UV absorption maxima and peak shift. Acyclovir with A. sativum (1-6%),
sooktybhasma 20% with rantidine, Ciprofloxacin HCl (2%) with 10% aqueous datura and Ciprofloxacin HCl (0.02-0.2%) with 0.02-0.06%
acetonitrile turmeric showed best integration result. This drug integration can be applied to improve the potential results or detoxification of hybrid
drugs that target the drug moiety results in reduced side effects or the dose of important drugs, which might be due to the chelation pattern of their
functional group, absorption, bonding, and pi-pi interaction.

Conclusion:
This study will provide the leadership for the betterment of a therapeutic hybrid drug complex that might be useful as an allopathic drug and less
harmful than its ayurvedic component. The proposed integration fusion of different medication therapies, such as Ayurvedic and allopathic, has the
potential for a scientific merger.
Small Non-coding RNA in Plants: From Basic Science to Innovative
Applications
Authors: Tarquini Giulia , Cione Erika 
Published: April 2023

Abstract:
Plants possess an arsenal of different classes of small RNAs (sRNAs) of variable size, which play a regulatory role in a multitude of physiological and pathological processes via tran-scriptional or post-transcriptional gene silencing. The hard challenges that agriculture will face in the next few decades, such as an increasing demand for agrifood production related to the global in-crease in population, have stimulated the development of innovative biotechnological approaches in agriculture. In this regard, the use of artificial sRNAs has already been exploited successfully for many purposes, including control of severe plant diseases, improvement of genetic and agronomic traits of cultivated species, and increasing the nutritional value of plant foodstuffs. This strategy re-lies on the application of synthetic sRNA molecules to induce specific physiological responses by triggering appropriate RNA silencing pathways. This review contextualizes the use of artificial sRNAs in consideration of the huge diversity of RNA silencing mechanisms in plants. Additionally, the discussion also examines microRNAs from edible plants and exosome-like vesicles, also known as plant-derived edible nanoparticles (ENPs), which themselves can act as micronutrients.
Effect of Rapid Urbanization in Mainland China on the Seasonal Influenza Epidemic: Spatiotemporal Analysis of Surveillance Data From 2010 to 2017
Authors: Lei Hao , Zhang Nan , Niu Beidi , Wang Xiao , Xiao Shenglan , Du Xiangjun , Chen Tao , Yang Lei , Wang Dayan , Cowling Benjamin , Li Yuguo , Shu Yuelong 
Published: April 2023

Background
The world is undergoing an unprecedented wave of urbanization. However, the effect of rapid urbanization during the early or middle stages of urbanization on seasonal influenza transmission remains unknown. Since about 70% of the world population live in low-income countries, exploring the impact of urbanization on influenza transmission in urbanized countries is significant for global infection prediction and prevention.

Objective
The aim of this study was to explore the effect of rapid urbanization on influenza transmission in China.

Methods
We performed spatiotemporal analyses of province-level influenza surveillance data collected in Mainland China from April 1, 2010, to March 31, 2017. An agent-based model based on hourly human contact–related behaviors was built to simulate the influenza transmission dynamics and to explore the potential mechanism of the impact of urbanization on influenza transmission.

Results
We observed persistent differences in the influenza epidemic attack rates among the provinces of Mainland China across the 7-year study period, and the attack rate in the winter waves exhibited a U-shaped relationship with the urbanization rates, with a turning point at 50%-60% urbanization across Mainland China. Rapid Chinese urbanization has led to increases in the urban population density and percentage of the workforce but decreases in household size and the percentage of student population. The net effect of increased influenza transmission in the community and workplaces but decreased transmission in households and schools yielded the observed U-shaped relationship.

Conclusions
Our results highlight the complicated effects of urbanization on the seasonal influenza epidemic in China. As the current urbanization rate in China is approximately 59%, further urbanization with no relevant interventions suggests a worrisome increasing future trend in the influenza epidemic attack rate.
Evaluating the Discriminatory Ability of the Sickle Cell Data Collection Program’s Administrative Claims Case Definition in Identifying Adults With Sickle Cell Disease: Validation Study
Authors: Singh Ashima , Sontag Marci K , Zhou Mei , Dasgupta Mahua , Crume Tessa , McLemore Morgan , Galadanci Najibah , Randall Eldrida , Steiner Nicole , Brandow Amanda M , Koch Kathryn , Field Joshua J , Hassell Kathryn , Snyder Angela B , Kanter Julie 
Published: April 2023

Background
Sickle cell disease (SCD) was first recognized in 1910 and identified as a genetic condition in 1949. However, there is not a universal clinical registry that can be used currently to estimate its prevalence. The Sickle Cell Data Collection (SCDC) program, funded by the Centers for Disease Control and Prevention, funds state-level grantees to compile data within their states from various sources including administrative claims to identify individuals with SCD. The performance of the SCDC administrative claims case definition has been validated in a pediatric population with SCD, but it has not been tested in adults.

Objective
The objective of our study is to evaluate the discriminatory ability of the SCDC administrative claims case definition to accurately identify adults with SCD using Medicaid insurance claims data.

Methods
Our study used Medicaid claims data in combination with hospital-based medical record data from the Alabama, Georgia, and Wisconsin SCDC programs to identify individuals aged 18 years or older meeting the SCDC administrative claims case definition. In order to validate this definition, our study included only those individuals who were identified in both Medicaid’s and the partnering clinical institution’s records. We used clinical laboratory tests and diagnostic algorithms to determine the true SCD status of this subset of patients. Positive predictive values (PPV) are reported overall and by state under several scenarios.

Results
There were 1219 individuals (354 from Alabama and 865 from Georgia) who were identified through a 5-year time period. The 5-year time period yielded a PPV of 88.4% (91% for data from Alabama and 87% for data from Georgia), when only using data with laboratory-confirmed (gold standard) cases as true positives. With a narrower time period (3-year period) and data from 3 states (Alabama, Georgia, and Wisconsin), a total of 1432 individuals from these states were included in our study. The overall 3-year PPV was 89.4% (92%, 93%, and 81% for data from Alabama, Georgia, and Wisconsin, respectively) when only considering laboratory-confirmed cases as true cases.

Conclusions
Adults identified as having SCD from administrative claims data based on the SCDC case definition have a high probability of truly having the disease, especially if those hospitals have active SCD programs. Administrative claims are thus a valuable data source to identify adults with SCD in a state and understand their epidemiology and health care service usage.
PENGARUH KONTRIBUSI PAJAK RESTORAN, PAJAK HIBURAN, PAJAK HOTEL, DAN PAJAK PENERANGAN JALAN TERHADAP PENDAPATAN ASLI DAERAH DI KOTA CIMAHI
Authors: Amelia Vera , Ishak Jouzar Farouq 
Published: April 2023

Tujuan penelitian ini untuk memahami bagaimana pengaruh kontribusi pajak restoran, pajak hiburan, pajak hotel, dan pajak penerangan jalan terhadap penerimaan PAD di Kota Cimahi dari 2016-2020, dengan simultan dan parsial. Metode yang dipakai adalah kuantitatif melalui pendekatan deskriptif pada data sekunder yakni Laporan Bulanan Penerimaan Pendapatan Daerah Kota Cimahi dari 2016-2020 yang dikerjakandengan IBM SPSS Statictics Versi 25.0. Sampel pada penelitian ini yaitu 60 bulan. Hasil penelitian ini membuktikan bahwa pajak restoran, pajak hiburan, pajak hotel, dan pajak penerangan jalan secara individumaupun bersama-sama tidak terdapat pengaruh yang signifikan terhadap PAD di Kota Cimahi.
MEDIA PEMBELAJARAN INTERAKTIF MATAKULIAH PENGGUNAAN DAN PENGATURAN MOTOR LISTRIK DENGAN MEMANFAATKAN TEKNOLOGI FLASH
Authors: Solihin Muhammad Dani , Astrid Erita , Siregar Rosma , Isnaini Muhammad , Hutahaean Harvei Desmon 
Published: April 2023

Abstrak: Media pembelajaran merupakan hal yang sangat penting dalam proses pembelajaran. Media pembelajaran yang baik sangat efektif digunakan dalam pembelajaran. Peneliti mengembangkan media pembelajaran interaktif dengan tujuan untuk menghasilkan produk berupa media pembelajaran dalam bentuk CD Interaktif yang dapat digunakan dalam proses pembelajaran. Media pembelajaran pada penelitian ini berdasarkan model desain ADDIE (Analysis, Design, Development, Implementation, and Evaluation). Adapun metode penelitian dilakukan dengan menggunakan langkah-langkah penggunaan metode research and development (R & D). Hasil penelitian menunjukkan CD Interaktif ternyata mendapat respon antusias dari mahasiswa dan sangat efektif digunakan dalam pembelajaran. Kata kunci: Media Pembelajaran, Model ADDIE, Penelitian dan Pengembangan Abstrack: Learning media is very important in the learning process. Good learning media is very effective in learning. Researchers develop interactive learning media with the aim of producing products in the form of learning media in the form of Interactive CDs that can be used in the learning process. The learning media in this study are based on the ADDIE design model (Analysis, Design, Development, Implementation, and Evaluation). The research method is carried out using the steps of using research and development (R & D) methods. The results showed that the Interactive CD received an enthusiastic response from students and was very effective in teaching and learning. Keywords: Learning Media, ADDIE Model, Research and Development
KOMPETENSI BERPIKIR INOVATIF GURU STUDI KASUS SMPN 10 SINGKAWANG
Authors: . Noni , Astuti Indri , . Afandi 
Published: April 2023

Abstrak: Proses pendidikan yang dilaksanakan harus berjalan secara optimal, oleh karena itu guru memiliki peran penting dalam mengembangkan dan merancang sebuah pembelajaran agar memberikan pengalaman belajar yang maksimal bagi siswa. Kompetensi guru yang inovatif harus dimiliki guru saat ini. Penelitian ini bertujuan untuk melihat dan menilai kompetensi inovatif guru di SMPN 10 Singkawang. Sampel dalam penelitian ini adalah seluruh 15 guru yang mengajar di SMPN 10 Singkawang dengan mengisi angket kompetensi inovatif guru. Kuesioner terdiri dari 4 indikator yaitu mengamati, bertanya, berjejaring ide dan bereksperimen. Penilaian kompetensi yang inovatif sangat membantu dalam memberikan gambaran tentang kualitas yang dimiliki guru sehingga dapat dilakukan perbaikan untuk menjadi lebih baik lagi. Kualitas guru di SMPN 10 Singkawang tergambar dengan jelas dalam hasil penelitian, guru di SMPN 10 Singkawang memiliki kompetensi guru yang inovatif dengan kriteria baik. (Rata-rata: 73,03). Kata Kunci: Kompetensi, Inovatif, Guru, Kuisioner. Abstract: The educational process carried out must run optimally, therefore the teacher has an important role in developing and designing a lesson in order to provide a maximum learning experience for students. Innovative teacher competencies must be owned by today's teachers. This study aims to see and assess the competence of innovative teachers at SMPN 10 Singkawang. The sample in this study were 15 teachers who teach at SMPN 10 Singkawang by filling out an innovative teacher competency questionnaire. The questionnaire consists of 4 indicators, namely observing, asking questions, networking ideas and experimenting. Innovative competency assessments are very helpful in providing an overview of the qualities possessed by teachers so that improvements can be made for the better. The quality of teachers at SMPN 10 Singkawang is clearly reflected in the results of the study, teachers at SMPN 10 Singkawang have innovative teacher competencies with good criteria. (Average: 73.03). Keywords: Competence, Innovative, Teacher , Questionnaire.
PENGARUH MODEL PEMBELAJARAN LANGSUNG (DIRECT INTRUCTION) BERBANTUAN MEDIA HAND OUT TERHADAP HASIL BELAJAR DASAR POLA SISWA KELAS X TATA BUSANA SMK NEGERI 1 STABAT
Authors: Sinukaban Veronica Yulisna , Vetricia Damai Linda Gea , . Ambiyar , Zaus Mahesi Agni 
Published: April 2023

Abstrak: Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran langsung berbantuan media hand out terhadap hasil belajar dasar pola pada siswa kelas X Tata busana di SMK Negeri 1 Stabat tahun ajaran 2016/2017. Jenis penelitian ini menggunakan metode quasi eksperimen dengan desain penelitian Post Test Only Design. Pengambilan sampel dilakukan dengan teknik total sampling dari populasi seluruh siswa kelas X Tata Busana SMK Negeri 1 Stabat yang terdiri kelas X-1 yang berjumlah 35 orang sebagai kelas eksperimen dengan menggunakan model pembelajaran langsung (Direct Intruction) berbantuan Media Hand out dan X-2 yang berjumlah 35 orang sebagai kelas kontrol dengan menggunakan model pembelajaran konvensional berbantuan Media hand out. Instrumen yang digunakan dalam penelitian ini adalah lembar pengamatan yang telah dinyatakan valid oleh validator. Hasil perhitungan uji hipotesis dengan uji t diperoleh thitung > ttabel (20,05 > 1,66), yang artinya bahwa Hipotesis alternatif (Ha) diterima, yaitu adanya pengaruh yang positif dan signifikan tinggi pada hasil belajar pembuatan pola dasar badan atas dengan teknik draping dengan menggunakan model pembelajaran langsung (Direct Intruction) berbantuan media hand out pada siswa kelas X Tata Busana SMK Negeri 1 Stabat. Kata Kunci: Direct Intruction, Media Hand Out, Hasil Belajar ABSTRACTThis researh have purpose to know the effect of direct instruction model aided hand out media toward learning outcomes of basic patterns in class X fashion at vocational high school 1 Stabat in academic years 2016/2017. The type of researh is quasi-experiment with design Post Test Only Design. The sampel was take by using total sampling, that is class X-2 which totaled 35 people as experiment class using direct intruction model assisted hand out media and X-1 which totaled 35 people as control class using conventional learning models aided hand outs media. The instrument used in this research is the observation sheet that has been declared valid by the validator. The calculation result of hypothesis testing by t test obtained tcount > ttable (20.05 > 1.66), which means that the alternative hypothesis (Ha) is accepted. the existence of positive and significant influence on the learning result of basic pattern making upper body with a draping technique using direct intruction model aided hand out media in class X fashion at vocational high school 1 Stabat. Keywords: Direct Intruction, Hand Out, Learning Outcomes.
En los orígenes del anarquismo agrario: el campesinado malagueño y la "Federación Regional Española" de la A.I.T.
Authors: Morales Muñoz Manuel 
Published: April 2023

Comúnmente olvidado por la historiografía dedicada al anarquismo rural andaluz, el objetivo de este artículo es describir la organización del campesinado malagueño en las filas de la Federación Regional Española (F.R.E.), desde sus orígenes, en julio de 1872, hasta su disolución el año 1874. Sus primeros pasos, con la creación de la sección de Hortelanos; la huelga de dignidad mantenida por estos durante el otoño-invierno de 1872-73; la extensión del "ideal" anarcocolectivista por la provincia, tras el Congreso de Córdoba (25.XII.1872-1.I.1873), y su paso a la clandestinidad, coincidiendo con la disolución de la F.R.E., son las cuestiones tratadas.
La ciudad como escenario para la muerte en el siglo XIX: honras funebres de M. A. Heredia en Málaga
Authors: Ordóñez Vergara Javier 
Published: April 2023

En su aparente normalidad, el funeral del hasta entonces principal representante de la burguesía malagueña es determinante y significativo de los intereses y las pautas que dominan el marco urbano decimonónico, donde las clases dirigentes hacen de sus actuaciones personales hechos de gran magnitud y resonancia, que infieren radicalmente, aunque de forma eventual, en el paisaje habitual de la ciudad y en la vida y actividad de sus habitantes.
La mujer esclava en España en los comienzos de la Edad Moderna
Authors: Lobo Cabrera Manuel 
Published: April 2023

Quizá la condición de objeto que tenían los seres humanos en el esclavismo diluya, al estudiarlos, la identificación sexual. Sin embargo, era frecuente la preferencia por las hembras frente a los varones. Aquéllas reunían una serie de condiciones que las hacían más apetecibles para sus compradores: eran trabajadoras domésticas o en todo tipo de trabajos como los varones, pero además eran vientres fecundos capaces de aumentar el ganado humano al tiempo que se convertían en objeto de placer de sus amos. Estos aspectos son los que analiza el autor en este artículo para situar en su contexto a las mujeres esclavas.
Notas sobre la Historia Antigua en el ocaso del mundo ilustrado: el Discurso sobre el origen de la monarquía y sobre la naturaleza del gobierno español de F. Martínez Marina
Authors: Wulff Alonso Fernando 
Published: April 2023

El autor plantea una visión del tratamiento de la Historia Antigua y especialmente de la Historia Antigua de España en Martínez Marina, un autor clave para entender el tránsito de una historiografia ilustrada a otra ligada a los intereses de la historiografía de la época romántica.
Religiosidad institucionalizada en el municipio malagueño
Authors: Reder Gadow Marion 
Published: April 2023

Atendiendo a la bula papal de Clemente X, de febrero de 1671, la Reina Doña Mariana de Austria, gobernadora de la Monarquía española durante la minoría de edad de Carlos II, ordenó a todas las Iglesias del Reino conmemorar ciertos acontecimientos religiosos con el mayor esplendor. Así mismo, exhortó a los cabildos municipales a concurrir solemnemente a estos actos que la iglesia mayor local programaba.
El Reino de Granada en tiempo de repoblación. Avisos y arbitrios contra la decadencia (a propósito de unos Memoriales de Pedro Mexía de Quemada)
Authors: Barrios Aguilera Manuel 
Published: April 2023

Sobre la base de unos memoriales, de clara progenie arbitrista, dirigidos a Felipe II por el clérigo Pedro Mexía de Quemada, completados por otros de semejante temática, se analiza la inconveniencia de los arrendamientos ordenados por la Corona en los lugares denominados "Valles, Llanos y Vegas", especialmente de la Vega de Granada, causa, en opinión de los memorialistas de un sinfín de males que ya habían conducido a una situación de decadencia, apenas pasados tres años de la expulsión de los moriscos, que se convertiría en irremediable, de no adoptarse el recurso de la dación a censo enfitéutico que caracterizó la repoblación de las "Alpujarras, Sierras y Marinas". Se aventura por el autor una polémica que debió tener cierta consideración en las altas esferas del gobierno y entre las autoridades civiles y eclesiásticas del Reino de Granada.