bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effectiveness of the platelet-rich fibrin in the control of pain associated with alveolar osteitis: a scoping review
Authors: La Rosa Giusy Rita Maria , Marcianò Antonia , Priolo Carlotta Ylenia , Peditto Matteo , Pedullà Eugenio , Bianchi Alberto 
Published: April 2023

Abstract

Objectives
The aim of this scoping review was to determine the effectiveness of the platelet-rich fibrin in the control of pain associated with alveolar osteitis.

Materials and methods
Reporting was based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Extension for Scoping Reviews. A literature search was conducted in the PubMed and Scopus databases to identify all clinical studies on the application of platelet-rich fibrin in the control of pain caused by alveolar osteitis. Data were extracted independently by two reviewers and qualitatively described.

Results
The initial search returned 81 articles, with 49 identified after duplicates removal; of these, 8 were selected according to the inclusion criteria. Three of the eight studies were randomized controlled clinical trials, and four were non-randomized clinical studies, two of which were controlled. One study was case series. In all of these studies, pain control was evaluated using the visual analog scale. Overall, the use of platelet-rich fibrin resulted effective in the control of pain determined by alveolar osteitis.

Conclusions
Within the limits of this scoping review, the application of platelet-rich fibrin in the post-extra-extraction alveolus reduced the pain associated with alveolar osteitis in almost all the included studies. Nevertheless, high-quality randomized trials with adequate sample size are warranted to draw firm conclusions.

Clinical relevance
Pain associated with alveolar osteitis causes discomfort to the patient and is challenging to be treated. Use of platelet-rich fibrin could be a promising clinical strategy for pain control in alveolar osteitis if its effectiveness will be confirmed by further high-quality studies.
On the convergence of numerical integration as a finite matrix approximation to multiplication operator
Authors: Sarmavuori Juha , Särkkä Simo 
Published: April 2023

AbstractWe study the convergence of a family of numerical integration methods where the numerical integration is formulated as a finite matrix approximation to a multiplication operator. For bounded functions, convergence has already been established using the theory of strong operator convergence. In this article, we consider unbounded functions and domains which pose several difficulties compared to the bounded case. A natural choice of method for this study is the theory of strong resolvent convergence which has previously been mostly applied to study the convergence of approximations of differential operators. The existing theory already includes convergence theorems that can be used as proofs as such for a limited class of functions and extended for a wider class of functions in terms of function growth or discontinuity. The extended results apply to all self-adjoint operators, not just multiplication operators. We also show how Jensen’s operator inequality can be used to analyse the convergence of an improper numerical integral of a function bounded by an operator convex function.
The effect of preservation on biomass and length estimates and its variation within and between two mayfly species
Authors: Dekanová Vladimíra , Streberová Zuzana , Novikmec Milan , Svitok Marek 
Published: April 2023

AbstractBiomass estimation offers insight into aquatic ecosystem processes and represents a powerful tool for measuring biomass in communities. However, the accuracy of this estimate depends considerably on the sample preservation method and biological traits of species. We quantified the effect of commonly used preservatives (70% ethanol, 4% formaldehyde, freezing), preservation time and initial body length on the estimation bias of body length, wet mass and dry mass in two mayfly species with dorsoventrally flattened (Rhithrogena carpatoalpina) and cylindrically elongated (Habroleptoides confusa) bodies. Freezing caused the largest relative bias in the length estimates (up to 18%). Both ethanol and freezing led to significant underestimation of wet mass of preserved animals (up to 26%). The most severe biases were observed in dry weights, where all preservation methods reduced body mass by up to 89%. Importantly, initial body mass influenced the bias caused by preservation, and the larger animals were less affected by mass losses. In contrast, larger individuals were subject to greater length reduction. Additionally, the length–mass relationship for R. carpatoalpina, based on fresh mass of living animals, was significantly different from relationships based on preserved animals. Overall, formaldehyde caused the least biased estimates of length and biomass in both examined species. This case study indicates that direct measurements of unpreserved individuals or length–mass equations based on fresh material are likely the best ways to avoid severe underestimation of biomass in aquatic insects. However, more studies covering a broader range of taxa are needed to reach general conclusions.
Bryophyte diversity, composition and functional traits in relation to bedrock and tree species composition in close-to-nature managed forests
Authors: Kutnar Lado , Kermavnar Janez , Sabovljević Marko S. 
Published: April 2023

AbstractBryophytes respond to a variety of environmental factors, including tree species composition and geological conditions, which are influenced by both natural and anthropogenic factors. Bryophytes growing on a variety of substrates were identified in ICP Forests monitoring plots in a wide range of close-to-nature managed forests, from lowland to high mountain areas in Slovenia. Based on data on tree layer composition (broadleaves vs. conifers) and on bedrock and soil type (calcareous vs. siliceous bedrock), all study plots were classified into five groups representing forest types. Different ordination analyses and statistical tests were used to represent differences between forest types in bryophyte composition, richness and functional traits. Almost 200 bryophyte species were identified in managed forests, with the most common being Hypnum cupressiforme, Brachytheciastrum velutinum and Polytrichum formosum. Bryophyte species composition varied considerably along the tree species composition and edaphic gradients represented by the selected forest types. Bryophyte species richness was significantly higher on calcareous bedrock than on siliceous bedrock. The higher occurrence of rocks on the ground surface may significantly increase the availability of various microhabitats for bryophytes. Bedrock had a significant influence on the functional diversity and composition of bryophytes, while tree species composition had less influence. Bedrock and tree species composition are important drivers of bryophyte species composition and diversity at taxonomic and functional trait levels. The high diversity of bryophyte species in Slovenian forests can also be attributed to close-to-nature and sustainable forest management practices that preserve favourable microclimatic conditions in forest stands and maintain diverse substrates.
Rant or rave: variation over time in the language of online reviews
Authors: Ziser Yftah , Webber Bonnie , Cohen Shay B. 
Published: April 2023

AbstractWe examine how the language of online reviews has changed over the past 20 years. The corpora we use for this analysis consist of online reviews, each of which is paired with a numerical rating. This allows us to control for the perceived sentiment of a review when examining its linguistic features. Our findings show that reviews have become less comprehensive, and more polarized and intense. We further analyzed two subgroups to understand these trends: (1) reviews labeled “helpful” and (2) reviews posted by persistent users. These trends also exist for helpful reviews (albeit in a weaker form), suggesting that the nature of reviews perceived as helpful is also changing. A similar pattern can be observed in reviews by persistent users, suggesting that these trends are not simply associated with new users but represent changes in overall user behavior. Additional analysis of Booking.com reviews indicates that these trends may reflect the increasing use of mobile devices, whose interface encourages briefer reviews. Lastly, we discuss the implications for readers, writers, and online reviewing platforms.
Comparative toxicological evaluations of novel forms nano-pesticides in liver and lung of albino rats
Authors: Abdel-Azeem Abeer M. , Abdel-Rehiem Eman S. , Farghali Ahmed A. , Khidr Fatma K. , Abdul-Hamid Manal 
Published: April 2023

AbstractCopper oxide Nanoparticles (CuONPs) are used in different agricultural applications. Large amounts of CuONPs cause organ dysfunction in animals. Our study aim to compare between the toxic effects of CuONanSphere (CuONSp) and CuONanoFlower (CuONF) as new nano-pesticides, determine a less toxic form when used in agricultural applications. To characterize CuONSp and CuONF, we used X-ray diffraction (XRD), Field emission scanning electron microscopy (SEM), and High resolution transmission electron microscopy (HRTEM) and Zeta-sizer device.18 adult male albino rats were divided into three groups (n = 6), (I) control group, (II) and (III) groups were given orally 50 mg/kg/day of CuONSp and CuONF 30 days respectively. CuONSp induced oxidant-antioxidant abnormalities, including an increase in malondialdhyde (MDA) and a decrease in glutathione (GSH) in comparison to CuONF-treated one. CuONSp induced an increase in liver enzymes activities compared to CuONF. Tumour necrosis factor-alfa (TNF-α) detected an increased in liver and lung compared to CuONF. However, histological examinations revealed changes in CuONSp group than CuONF group. Changes in immune-expressions of TNF-α, nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kβ) and tumour suppressor gene (p53) were also more identified in CuONSp group than CuONF group. Ultrastructural studies of liver and lung tissues marked alternations were observed in CuONSp group than CuONF group. In conclusion, CuONSp induced biological alternation in liver and lung more than CuONF. So, CuONF is less toxic compared to CuONSp when used as nano-pesticide in agricultural applications.
Graphical abstract
Video steganography: recent advances and challenges
Authors: Kunhoth Jayakanth , Subramanian Nandhini , Al-Maadeed Somaya , Bouridane Ahmed 
Published: April 2023

AbstractVideo steganography approach enables hiding chunks of secret information inside video sequences. The features of video sequences including high capacity as well as complex structure make them more preferable for choosing as cover media over other media such as image, text, or audio. Video steganography is a prominent as well as the evolving field in the information security domain and significant number of video steganography methods are proposed in recent years. This article provides a comprehensive review of video steganography methods proposed in the literature. This article initially reviews various raw domain-based video steganography methods. In particular, the raw domain-based methods include spatial domain approaches such as least significant bits (LSB), transform domain-based methods such as discrete wavelet transform, discrete cosine transform, etc. Furthermore, the article looks into various compressed domain steganography methods. A critical comparative analysis is included in the article to analyze and contrast the steganography methods proposed in the literature. A brief description of various evaluation matrices for video steganography methods is provided in this article. Moreover, a brief introduction to steganalysis and video steganalysis is provided. The article concludes with a discussion focused on the limitations and challenges of the video steganography methods. Further, a brief insight into future directions in video steganography systems is provided.
Entrepreneurial ecosystems, institutional quality, and the unexpected role of the sustainability orientation of entrepreneurs
Authors: Audretsch David Bruce , Belitski Maksim , Eichler Georg Maximilian , Schwarz Erich 
Published: April 2023

AbstractWhile research on entrepreneurship and entrepreneurial ecosystems (EEs) has consolidated over the last decade, one question remains unanswered: how can the sustainability orientation of EE actors facilitate the intensity and growth orientation of entrepreneurship in the ecosystem? Entrepreneurship activity relies on the sustainability orientation of the ecosystem, which is lacking in most developing countries where reaching the UN’s Sustainable Development Goals (SDGs) is the most pressing concern. Using primary data on 1789 EE actors from 17 cities in East and South-East Europe and econometric analysis techniques, we investigate the relationship between the sustainability orientation of EE actors and EE outcomes. We find that this relationship is conditional on the country’s institutional quality and is consistent for a variety of EE outcomes. Practical implications for regional policymakers and entrepreneurs are developed.
Modeling Gender Life Expectancy Ratio in a Multi-population Framework
Authors: Cefalo Leonardo , Levantesi Susanna , Nigri Andrea 
Published: April 2023

AbstractThis paper aims to assess whether the male-to-female ratio in life expectancy is driven by cross-national long-period common trends. If a common trend is detected across a group of countries, then a model taking it into account should provide a more reliable description of the process in scope. We model the gender life expectancy ratio of a set of countries as a multivariate time series. Since our study includes data from 25 countries that are characterized by different longevity patterns, we preliminarily aggregate populations in clusters. Once we verify that all these series are non-stationary, we apply Johansen’s cointegration rank test to each cluster. The idea behind this methodology is to detect any stationary linear combination out of nonstationary variables, which implies that the series share some underlying long-period equilibrium relationships. If the cointegration rank test provides evidence for any cointegrating relationship, we further check whether estimated linear combinations of the single series - namely the error correction terms - are stationary. Finally, we measure forecasting errors with respect to the 10-year testing set. At least for two clusters over six, we find enough evidence to outline some cointegrating relationships in the male-to-female life expectancy ratio. This result leads us to assume that an underlying long-period equilibrium in life expectancy gender differentials does exist among the single countries included in these clusters.
The transcription regulator ATF4 is a mediator of skeletal muscle aging
Authors: Miller Matthew J. , Marcotte George R. , Basisty Nathan , Wehrfritz Cameron , Ryan Zachary C. , Strub Matthew D. , McKeen Andrew T. , Stern Jennifer I. , Nath Karl A. , Rasmussen Blake B. , Judge Andrew R. , Schilling Birgit , Ebert Scott M. , Adams Christopher M. 
Published: April 2023

AbstractAging slowly erodes skeletal muscle strength and mass, eventually leading to profound functional deficits and muscle atrophy. The molecular mechanisms of skeletal muscle aging are not well understood. To better understand mechanisms of muscle aging, we investigated the potential role of ATF4, a transcription regulatory protein that can rapidly promote skeletal muscle atrophy in young animals deprived of adequate nutrition or activity. To test the hypothesis that ATF4 may be involved in skeletal muscle aging, we studied fed and active muscle-specific ATF4 knockout mice (ATF4 mKO mice) at 6 months of age, when wild-type mice have achieved peak muscle mass and function, and at 22 months of age, when wild-type mice have begun to manifest age-related muscle atrophy and weakness. We found that 6-month-old ATF4 mKO mice develop normally and are phenotypically indistinguishable from 6-month-old littermate control mice. However, as ATF4 mKO mice become older, they exhibit significant protection from age-related declines in strength, muscle quality, exercise capacity, and muscle mass. Furthermore, ATF4 mKO muscles are protected from some of the transcriptional changes characteristic of normal muscle aging (repression of certain anabolic mRNAs and induction of certain senescence-associated mRNAs), and ATF4 mKO muscles exhibit altered turnover of several proteins with important roles in skeletal muscle structure and metabolism. Collectively, these data suggest ATF4 as an essential mediator of skeletal muscle aging and provide new insight into a degenerative process that impairs the health and quality of life of many older adults.
Entrepreneurial intention and creative performance – the role of distress tolerance
Authors: Caniëls Marjolein C. J. , Motylska-Kuźma Anna 
Published: April 2023

AbstractThe Person-Entrepreneurship fit perspective poses that individuals are drawn to work settings that match their personal preferences, attitudes and goals. We argue that compatibility between personal attributes of individuals and their intention to become an entrepreneur is positively associated to creative (entrepreneurial) performance. While previous studies have branded trait creativity as an important personal resource for entrepreneurs, research has yet to investigate entrepreneurial intention as antecedent of entrepreneurs’ creative performance. Therefore, this two-wave study investigates the conditions under which entrepreneurial intentions of student entrepreneurs are related to their creative performance. Specifically, we investigate the three-way interaction between entrepreneurial intention, opportunity recognition and distress tolerance in determining creative performance in a sample of 142 Polish student entrepreneurs. We use Hayes’ process function for R to examine the hypothesized three-way moderation effect (Model template 3). Theoretical contributions of this study lie in (1) advancing theory on creative performance in the context of entrepreneurship, as well as (2) extending the work on Person-Entrepreneurship fit, by establishing a contingency model in which individuals aiming at entrepreneurship and having specific personal attributes may be more likely to display entrepreneurial creativity under certain conditions. Findings indicate that opportunity recognition and distress tolerance act as boundary conditions, moderating the intention-performance relationship. The relationship between entrepreneurial intention and creative performance only holds for entrepreneurs with high levels of opportunity recognition. Moreover, low distress tolerance impedes the stimulating effect of opportunity recognition on the relationship between entrepreneurial intention and creative performance.
Quantification of olanzapine and its three metabolites by liquid chromatography–tandem mass spectrometry in human body fluids obtained from four deceased, and confirmation of the reduction from olanzapine N-oxide to olanzapine in whole blood in vitro
Authors: Nozawa Hideki , Minakata Kayoko , Hasegawa Koutaro , Yamagishi Itaru , Miyoshi Naotomo , Suzuki Masako , Kitamoto Takuya , Kondo Minako , Watanabe Kanako , Suzuki Osamu 
Published: April 2023

Abstract
Purpose
Quantification of olanzapine (OLZ) and its metabolites such as N-desmethylolanzapine (DM-O), 2-hydroxymethylolanzapine (2H-O) and olanzapine N-oxide (NO-O) in five kinds of human body fluids including whole blood by liquid chromatography (LC)–tandem mass spectrometry (MS/MS) has been presented; the quantification methods were carefully devised and validated using the matrix-matched calibration and standard addition methods.

Methods
OLZ and its three metabolites were extracted from 40 μL each of body fluids by two-step liquid–liquid separations. The samples and reagents were pre-cooled in a container filled with ice for the extraction because of the thermal instability of OLZ and its three metabolites especially in whole blood.

Results
The limits of quantification (LOQs) of OLZ and 2H-O were 0.05 ng/mL and those of DM-O and NO-O were 0.15 ng/mL in whole blood and urine, respectively. The concentrations of OLZ and its metabolites in heart whole blood, pericardial fluid, stomach contents, bile and urine were determined for two cadavers and those in whole blood and urine for the other two cadavers. The reduction from NO-O to OLZ was observed at 25 ℃ in whole blood in vitro.

Conclusions
To our knowledge, this is the first report on the quantification of metabolites of olanzapine in the authentic human body fluids by LC–MS/MS as well as on the confirmation of in vitro reduction from NO-O to OLZ in whole blood that seems to have induced the quick decrease of NO-O.
Higher body weight-dependent neural activation during reward processing
Authors: Richter Maike , Widera Sophia , Malz Franziska , Goltermann Janik , Steinmann Lavinia , Kraus Anna , Enneking Verena , Meinert Susanne , Repple Jonathan , Redlich Ronny , Leehr Elisabeth J. , Grotegerd Dominik , Dohm Katharina , Kugel Harald , Bauer Jochen , Arolt Volker , Dannlowski Udo , Opel Nils 
Published: April 2023

AbstractObesity is associated with alterations in brain structure and function, particularly in areas related to reward processing. Although brain structural investigations have demonstrated a continuous association between higher body weight and reduced gray matter in well-powered samples, functional neuroimaging studies have typically only contrasted individuals from the normal weight and obese body mass index (BMI) ranges with modest sample sizes. It remains unclear, whether the commonly found hyperresponsiveness of the reward circuit can (a) be replicated in well-powered studies and (b) be found as a function of higher body weight even below the threshold of clinical obesity. 383 adults across the weight spectrum underwent functional magnetic resonance imaging during a common card-guessing paradigm simulating monetary reward. Multiple regression was used to investigate the association of BMI and neural activation in the reward circuit. In addition, a one-way ANOVA model comparing three weight groups (normal weight, overweight, obese) was calculated. Higher BMI was associated with higher reward response in the bilateral insula. This association could no longer be found when participants with obesity were excluded from the analysis. The ANOVA revealed higher activation in obese vs. lean, but no difference between lean and overweight participants. The overactivation of reward-related brain areas in obesity is a consistent finding that can be replicated in large samples. In contrast to brain structural aberrations associated with higher body weight, the neurofunctional underpinnings of reward processing in the insula appear to be more pronounced in the higher body weight range.
A new species of phytophagous flower fly (Diptera, Syrphidae), feeding on holoparasitic broomrape plants (Orobanchaceae) for the first time in Europe
Authors: Aracil Andrea , Grković Ana , Pérez-Bañón Celeste , Kočiš Tubić Nataša , Juan Ana , Radenković Snežana , Vujić Ante , Rojo Santos 
Published: April 2023

AbstractThe first data on the interaction between a phytophagous hoverfly and holoparasitic broomrape plants in Europe is reported. Description of the new species Eumerus larvatus sp. nov. Aracil, Grković et Pérez-Bañón is presented from specimens feeding within the fleshy hypogeal stems of Cistanche phelypaea in different localities of Southeast of Iberian Peninsula. Both, adult and preimaginal morphology are studied, including also a molecular analysis based on COI gene sequences. The molecular data, together with the diagnostic morphological characteristics of the adult, indicate that the species belongs to the Eumerus tricolor species-group. This paper presents the first in-depth and detailed description of the preimaginal morphology of a representative of this species group, based on scanning electron microscopy (SEM) images.