bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALISIS PENGARUH EARNING PER SHARE DAN RETURN ON EQUITY TERHADAP NILAI PERUSAHAAN
Authors: Wibowo Dedi , Agustina Risma Citra , Simamora Saur Cotanius 
Published: June 2023

This study aims to determine the effect of earnings per share and return on equity on company value. The sample in this study was PT Astra International Tbk in 2015-2019. This study used secondary data in the form of financial statements obtained from the www.idx.co.id website and the PT Astra International Tbk website. The analysis methods used are multiple linear regression analysis and data analysis using SPSS software version 25. The results of the study partially show that earnings per share have a significant effect on company value with significance 0,002 < 0,05, while return on equity does not have a significant effect on Company Value. The results of the study simultaneously show that earnings per share and return on equity affect the company's value by significance 0,006 < 0,05.
Keywords: Earning Per Share (EPS), Return On Equity (ROE), Nilai Perusahaan.
Factors associated with challenges in skin wound length and depth prediction of physicians in forensic cases
Authors: KOMUT Seval , GÜMÜŞ Burak , DOĞAN Burcu , ULUDAĞ Oğuz Kağan , YAĞCI Salih , BARINDIK Mert , ERENLER Ali Kemal 
Published: June 2023

Aim: We aimed to display factors associated with error rates in identifying skin lesions with subjective methods and determine potential effectiveness of objective and metric measurements on judicial processes which may result in unwanted social and legal outcomes and raise the awareness of physicians.
Material and Method: We made an incision on a piece of sponge with a lencet in order to model a skin lesion. The length and depth of the lesion was measured by compass device. Then, a face to face interview was planned with the physicians working in the hospital and they were asked to estimate the length and depth of the lesion. Estimations of the physicians were recorded.
Results: Total of 146 physicians were involved into the study. Of these, 41.8% (n=61) were female and 58.2% (n=85) were male. Mean age of the physicians was 33.46±7.94 (24-61) years. Of the physicians, 7.5% (n=11) were a member of basic medical sciences, 26% (n=38) were a member of surgical medical sciences and 21.9% (n=32) were practitioner physician. When titles of the physicians were investigated, it was found that 21.9% (n=32) were practitioners, 34.9% (n=51) were residents, 34.9% (n=51) were specialists, 8.2% (n=12) were lecturers. The rate of the participants who estimated the incision more than 8 cm was higher than those who estimated less than 8 cm. Standart deviation of the depth estimation was 1.35 cm. Thirty-nine (26.7%) participants made an exact estimation of the depth of the incision.
Conclusion: The measurement accuracy without a device is not associated with experience and errors of both inexperienced physicians and experienced physicians of any grade do similar mistakes during judicial report preparation process. These high error levels reveal that use of devices may avoid errors of physicians at any grade and protect physicians from possible judicial challenges.
YouTube as a source of patient information on positron emission tomography
Authors: GENÇ Mustafa 
Published: June 2023

Aim: With the technological developments and the widespread use of smart phones, patients frequently use the internet to get information. YouTube is also one of the most popular sources for patient information. Positron emission tomography is one of the most common and important imaging methods specific to nuclear medicine. The aim of this study was to investigate the videos on YouTube about positron emission tomography imaging.
Material and Method: This study was conducted in October 2022. Videos were accessed on YouTube using the keywords "positron emission tomography" and "pozitron emisyon tomografisi". These videos were evaluated using the global quality scale (GQS), the DISCERN scale, and the Journal of the American Medical Association (JAMA) benchmark criteria.
Results: In total, 123 videos were reviewed and 75 videos were included in the study. Most of these videos were uploaded by non-physician person. The number of views, the number of comments, the number of video likes and the viewing rate of the non-physician sourced videos were found to be higher than the physician sourced videos. On the other hand, JAMA scores, GQS scores and DISCERN scores of non-physician sourced videos were found to be lower than physician sourced videos. These findings were statistically significant. In addition, significant positive correlations were found between JAMA score, GQS score and DISCERN score.
Conclusions: Widely used YouTube platform for any information. Patients and their relatives can also search specifically for any disease and treatment. Physicians and specialty associations can upload official videos to the YouTube platform to ensure that patients have access to higher quality and more accurate content. URLs of these videos can also be added to patient information forms.
Retrospective analysis of 102 neonatal cases hospitalized with diagnosis of the ongoing phenomenon of neonatal period: hypernatremic dehydration
Authors: ÖZDİL Mine , VARDAR Gonca 
Published: June 2023

Aim: The aim of this study was to examine the prevalence of hypernatremic dehydration (HD) among term neonates admitted to a tertiary care unit over a three-year period and to identify mother and neonate related risk factors associated with HD.
Material and Method: Medical records of 102 term babies and their mothers were analyzed retrospectively. The gender, weight at birth, type of birth, postnatal day of diagnosis, weight and weight loss percentage at diagnosis, season and presenting complaint upon admission, feeding with human milk/formula/mixed, laboratory findings, usage of antibiotics as well as maternal age, parity, residence, level of education and presence of smoking were recorded. Serum sodium (Na) levels, severity of dehydration, age on admission, and length of stay in the neonatal intensive care unit (NICU) were recorded along with any significant effect of maternal demographic properties, residence, season, gender, and type of birth.
Results: The average Na levels were found to be 152.1±4.2 mEq/L (max:166 mEq/L). Mild, moderate and severe hypernatremia were found in 34 (33%), 62 (61%) and 6 (6%) patients, respectively. More weight loss was observed in neonates born via cesarean section vs. vaginal delivery (12.8±3.0% vs. 11.6±3.5%, p=0.01). Higher serum Na levels (153.9±4.86 mEq/L vs. 151±2.34 mEq/L, p=0.008) and a greater median age at admission (4.5 [IQR4-6]) days vs. 3 [IQR3-4]) days, p=0.03) were reported for neonates born to mothers residing in rural/suburban vs. urban areas. Serum Na levels were not different based on the mother's level of education or parity (p=0.96 and p=0.29, respectively). There was no difference in serum Na levels (p=0.05) but the percentage of weight loss was higher when the mother smoked (14.3±3.8% vs. 11.7±3.1%, p=0.003). Serum Na and glucose levels were lower, antibiotics usage rates, and prevalence of mixed feedings were higher in early term infants (p=0.01, p=0.002, p=0.04 and p=0.04, respectively). Males had higher creatinine levels (0.89±0.27 mg/dl vs. 0.78±0.28 mg/dl, p=0.005), but there was no difference between the sexes in terms of day of admission, percentage of weight loss, or length of stay in NICU.
Conclusion: Hypernatremic dehydration is a significant and increasingly prevalent problem of neonatal period. Serum Na levels and severity of dehydration in neonates may be affected by the type of birth, mother's smoking status, residence and early term birth. Counseling on breastfeeding, education of health professionals and caregivers on the signs and symptoms of dehydration, and monitoring of body weight are essential for the prevention, diagnosis, and treatment of HD.
A retrospective analysis on mucormycosis in patients with hematological diseases: a single center experience from Turkey
Authors: YILDIZHAN Esra , GÜVEN Zeynep Tuğba , KAYNAR Leylagül 
Published: June 2023

Aim: Mucormycosis is an acute, invasive, devastating and highly fatal fungal infection, affecting particularly immunocompromised patients; fortunately, it is rare. This study aimed to describe the attitude of mucormycosis in patients with a hematological disease, and to evaluate the risk factors associated with mortality.
Material and Method: We retrospectively assessed the demographic and clinical data of patients who were diagnosed with mucormycosis in Erciyes University Hematology and Bone Marrow Transplantation Center, between 2010 and 2020. The study was included 34 patients with a history of either hematological malignancy or hematopoietic stem cell transplantation.
Results: Twenty-seven patients had proven infection, and the others had possible infection. The most frequent underlying disease was acute leukemia. Seven-teen patients had a history of allogeneic transplantation, and frequency of mucormycosis was 3.5% among allogeneic transplant recipients. The most frequent site of infection was the rhino-orbital region (85.3%). Forty-seven percent of patients presented with acute orbital symptoms. Fifteen patients were on a mucor-active antifungal (posaconazole and liposomal Amphotericin B) prophylaxis or treatment at the time of diagnosis. All patients received liposomal Amphotericin B and seven patients received posaconazole additionally as initial therapy. Surgical debridement was performed in 91.1% of patients. The two-year mucor-related mortality rate was 44.1%. The survival curves were significantly lower in patients with concomitant fungal pneumonia, allogeneic transplantation and also in patients who were receiving mucor-active antifungal drugs at the time of diagnosis.
Conclusion: Mucormycosis remains a significant problem for hematology clinicians despite the expanding use of antifungal prophylaxis. Moreover, breakthrough infections indicate rising danger regarding resistant agents. We also highlight that, most of the patients receiving broad-spectrum antifungal prophylaxis are more fragile and more complicated patients, which put them at increased baseline risk for mucormycosis, and deserve more attention.
Demographic and clinical characteristics of patients with nonspecific esophageal motility disorder
Authors: TENLİK İlyas , ÖZTÜRK Ömer , ÖZDERİN Yasemin , BACAKSIZ Ferhat , ARI Derya , COŞKUN Orhan 
Published: June 2023

Aim: Although nonspecific esophageal motility disorder(NEMD) is the most common diagnosis in manometry, unlike other primary esophageal disorders, it is the least known and least studied disorder in the literature. Studies with a small number of patient groups have been reported in the literature. The aim of this study is to share the demographic and clinical characteristics of the single center high-volume NEMD patients we have followed up.
Material and Method: The study was carried out retrospectively by examining the motility records of 391 patients diagnosed with NEMD in the motility laboratory of the gastroenterology clinic of our hospital. 20-year motility laboratory records between 1991 and 2019 were reviewed.
Results: The mean age of 391 patients diagnosed with NEMD was 49.08±14.4 (18-90). 213 (54.5%) of them were female, and 178 (45.5%) of them were male. The primary symptom was reflux in 56.8% (222/391) of the patients, and dysphagia in 43.2% (169/391). While there was no esophagitis in 78.2% of the patients who had endoscopy, esophagitis was found in 21.8% of them. Pathological reflux was detected in 73.5% of the patients whose 24-hour pH was measured. In the repeated manometry results of patients due to increased complaints in their follow-up whose initial manometry findings were compatible with NEMD, 18 patients were diagnosed with achalasia, 5 patients with nutcracker esophagus, and 4 patients with diffuse esophageal spasm (DES).
Conclusion: The majority of patients with NEMD are associated with reflux. Patients with NEMD who do not have endoscopic and radiological organic disorders should be re-evaluated with manometry and further examinations if their complaints persist.
Evaluation of patellar tendon morphology in Turkish population: a cross-sectional study
Authors: KÖKSAL Ali , TUĞTAĞ DEMİR Berin , ÇANKAL Fatih 
Published: June 2023

Aim: This study aims to investigate the length, width and thickness of the patellar tendon and the type and length of the patella with MRI and to reveal the normal values ​​of patellar tendon morphology specific to the Turkish population.
Material and Method: The study was conducted with 348 individuals (137 males, 211 females) who applied to our hospital, had no anterior knee pathology, and had knee MRIs. The length, proximal and distal width and thickness of the patellar tendon, patella type, prepatellar and infrapatellar fat pad signal characteristics and Insall-Salvati ratio were evaluated on knee MRI images of these individuals.
Results: Type I patella was detected in 23.9%, type II in 57.2%, type III in 16.1%, and type IV in 2.9% of individuals. The mean length of the patella was 41.26±4.36 mm, the patellar tendon length was 47.36±6.70 mm, the proximal width was 28.86±3.49 mm, the distal width was 23.53±2.69 mm, the proximal thickness was 3,62±1.47 mm, and distal thickness was 5.21±1.1 mm. It was determined that the Insall-Salvati ratio did not cause a statistical difference according to age, but the patella type showed significance with the Insall-Salvati classification.
Conclusion: While evaluating MRI images, the effect of social differences on measurements should not be ignored; normal measurement values ​​of the tendon should be known to evaluate pathological measurements.
Effect of tocilizumab in subarachnoid hemorrhage-induced cerebral vasospasm of experimental rats
Authors: İZCİ Emir , KESKİN Fatih , KAYA Bulent , YERLİKAYA Fatma Hümryra , CÜCE Gökhan 
Published: June 2023

Aim: This study aimed to evaluate the effects of tocilizumab (TCZ), a recombinant humanized, anti-human monoclonal antibody of the immunoglobulin G1k subclass, on vascular morphological changes, endothelial apoptosis, and the levels of pro-inflammatory and apoptotic cytokines, such as IL-6, tumor necrosis factor-alpha (TNF-α), caspase-3, Bcl-2 associated X-protein (BAX), and vascular endothelial growth factor (VEGF) in a rat SAH model.
Material and Method: The rats were randomly assigned (animal study) to 4 groups KONÜDAM Experimental Animal Research Center, Necmettin Erbakan University, Meram Faculty of Medicine, Konya, Turkey; 15/03/2019): (1) normal control (without SAH); (2) SAH (without treatment); (3) SAH treated with saline (SAH + Sal.); and (4) SAH treated with TCZ (SAH + Toc.). The tissues were measured using enzyme-linked immunosorbent assay (ELISA) kits. A series of brain and basilar artery sections were categorized into several subgroups for hematoxylin and eosin (H&E) staining, immunohistochemistry, and Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) staining.
Results: The levels of caspase, BAX, and IL-6 in the SAH + TOC group were significantly lower than in other groups. TCZ treatment significantly increased the lumen of the basilar artery compared with that in the SAH and SAH + SAL groups without treatment (p=0.002 and p=0.004 respectively). SAH increased the apoptotic index in the endothelium compared with TCZ treatment (p=0.027) groups.
Conclusion: It can be concluded that TCZ is safe and effective for treating experimental SAH. The results reveal clearly experimental evidence for the potential clinical application of TCZ in SAH patients.
Fracture of the Petrous Carotid Canal
Authors: Yang Nathaniel 
Published: June 2023

A 23-year-old male motorcyclist experienced blunt head trauma with loss of consciousness, headache and vomiting, epistaxis and right otorrhagia after a collision with a motor vehicle. Fractures involving the right parietal and temporal bones, as well as acute subdural and subarachnoid hemorrhage were identified on a cranial and facial CT scan. On independent evaluation of the imaging study, a subtle but distinct fracture line in the skull base involving the petrous carotid canal was identified. (Figure 1) The patient subsequently underwent CT angiography to evaluate for any injury to the internal carotid artery. In this examination, good opacification of the internal carotid arteries and their branches was noted, with no evident aneurysm, arteriovenous malformation or arteriovenous fistula formation.
In patients with temporal bone fractures, the most commonly encountered complications are: tympano-ossicular injury causing conductive hearing loss, cochlear or vestibular injury causing sensorineural hearing loss or vertigo, facial nerve trauma causing facial paralysis, and fractures of the tegmen or posterior cranial fossa plate causing cerebrospinal fluid leaks.1 On the other hand, injury to the intratemporal portion of the internal carotid artery has been described as a rare complication and as such may be overlooked.1 However, its potentially devastating and life-threatening sequelae necessitates a purposeful and intentional evaluation for its presence. These sequelae include brain ischemia from arterial dissection or complete vascular occlusion, exsanguinating epistaxis or otorrhagia from carotid pseudoaneurysms, and the formation of carotid-cavernous fistulas.2 The incidence of involvement of the carotid canal in skull base fractures has been reported to be around 24%, with around 11% of this group developing internal carotid artery injuries.3 As such, the presence of fractures involving the petrous carotid canal is an indication for CT or MR angiography to further evaluate the internal carotid artery.4
Kewajiban Direksi untuk melakukan Permintaan Persetujuan Kepada Pemegang Saham dalam Pengalihan Aset Kekayaan Perseroan
Authors: Sukendar Abdullah Muhammad Assyad , Barkatullah Abdul Halim , Djumadi Djumadi 
Published: June 2023

Penelitian ini bertujuan menganalisa kewenangan Direksi dalam hal persetujuan pemegang saham dalam hal pengalihan aset perseroan dan untuk menganalisa penerapan sanksi terhadap Direksi apabila pengalihan aset tidak disertai dengan persetujuan pemegang saham. Maka dalam penelitian ini direksi memiliki kewenangan yang dibatasi bertindak secara intern, baik yang bersumber pada doktrin hukum maupun yang bersumber pada peraturan yang berlaku, termasuk anggaran dasar perseroan. Terkait dengan batasan direksi yang meminta persetujuan RUPS untuk mengalihkan aset perseroan baik menjadikan jaminan utang kekayaan perseroan yang jumlahnya lebih dari 50 % (lima puluh persen) dalam satu transaksi atau lebih itu merupakan kewajiban direksi. Maka persoalan mengalihkan aset perseroan ini akan sangat berdampak pada kelangsungan hidup perseroan yang harus diketahui dan diputuskan langsung oleh RUPS. Selain itu, penerapan sanksi terhadap direksi apabila pengalihan aset tidak disertai dengan persetujuan pemegang saham jika dilakukan dengan sengaja, maka direksi dapat dikatakan melakukan perbuatan yang melampaui kewenangan yang diberikan. Artinya Direksi telah melakukan tindakan ultra vires, sedangkan akibat dari tindakan ultra vires yang berakibat dapat merugikan Perseroan tersebut, maka tanggung jawab terbatas Direksi karena kesalahan Direksi adalah tanggung jawab pribadi, selain itu perbuatan direksi yang ultra vires dapat dikaitkan juga dengan perbuatan melawan hukum sebagaimana dirumuskan dalam Pasal 1365 KUH Perdata.
Desafíos del derecho a la protección de la salud en México
Authors: Martínez Lazcano Alfonso Jaime 
Published: June 2023

El presente artículo expone los criterios judiciales mexicanos y de la Corte Interamericana de Derechos Humanos, referentes a los parámetros del derecho a la protección de la salud del ámbito constitucional y convencional, la importancia de éste para el desarrollo humano, frente algunos datos capitales del escenario a salvaguardar, el cual representa un abismo entre lo que se dice que se pretende y la realidad, esencialmente por la pobreza y la desigualdad social que impera en Latinoamérica y específicamente en México.
Consejos comunitarios como eje central para la gobernanza territorial contra la deforestación en el departamento del chocó
Authors: Asprilla Panesso Edwin Samir , Posso Asprilla Javier Alexis , Restrepo Escobar Yuceth Bradley 
Published: June 2023

El presente artículo científico aborda desde una metodología de investigación cualitativa, el estudio de la deforestación en el departamento del chocó buscando responder a la pregunta de que si ¿los consejos comunitarios como entidades públicas de administración territorial afrodescendiente pueden para liderar los procesos de gobernanza territorial que se han de desarrollar en procura de, prevenir, mitigar y subsanar la deforestación en el departamento del chocó? esto con el objetivo de encontrar herramientas administrativas que permitan desarrollar procesos de participación plurales para el abordaje y solución de la problemática de la deforestación en el departamento.
Para tal fin se explica en primera medida que son y cómo se organizan los consejos comunitarios, así como explicar la base normativa sobre la que se erigen estos consejos comunitarios, para posteriormente abordar el estado actual de la deforestación departamental, para continuar con la gobernanza territorial como concepto y proceso de desarrollo y participación diversa que nos permita encontrar herramientas realistas para el tratamiento de la problemática de la deforestación y finalmente se abordan los resultados y conclusiones, donde se expone cómo la estructura de los consejos comunitarios y las experiencias de emprendimiento comercial en el departamento desarrolladas desde los consejos comunitarios, los convierten en instituciones más que interesantes para liderar los procesos de gobernanza territorial que puedan traducirse en la mitigación del fenómeno de la deforestación.
Las Garantías Judiciales y los Derechos Políticos en el Proceso Disciplinario Colombiano contra funcionarios de Elección Popular
Authors: Peña Sánchez Alcides , Soto Barrios Andrés , Cardona Arbeláez Diego 
Published: June 2023

La jurisdicción disciplinaria, en específico la competencia de la Procuraduría General de la Nación (PGN) en el ius puniendi colombiano, y la tradición procedimental disciplinaria, interpretada por la jurisprudencia de los procesos sancionatorios en Colombia, prima facie se encuentra en armonía con la normativa interamericana. No obstante, revisándose detalladamente sentencias internas e internacionales en donde se establece el alcance de la inhabilitación y destitución por la PGN en su poder preferente disciplinario, los controles de constitucionalidad, legalidad, convencionalidad de sus habilidades expuestas en el marco jurisprudencial nacional e internacional y analizando las estadísticas sobre funcionarios públicos elegidos popularmente suspendidos, destituidos e inhabilitados por procuradores, es evidente que existe una discordia institucional entre las corporaciones del ordenamiento jurídico interno y la Corte Interamericana de Derechos Humanos (CIDH). Habiéndose establecido la regla jurisprudencial cuando produjo el efecto de cosa juzgada constitucional en el 2006, se determinó la interpretación de la norma y sus implicaciones. Si bien fueron actualizadas, los vacíos pendientes y cuestiones surgentes se pueden convertir en lagunas de impunidad, por lo cual se aproximará la realidad normativa disciplinaria en Colombia dos años después del Caso Petro Urrego Vs. Colombia.