bluuebunny/crossref_metadata_2025_split huggingface dataset:
Electroactive Dyes Based on 1,8‐Naphthalimide with Acetylene Linkers as Promising OLED Materials – the Relationship Between Structure and Photophysical Properties
Authors: Matussek Marek , Kurpanik‐Wójcik Aneta , Gogoc Szymon , Fijołek Aleksandra , Filapek Michał , Naumczuk Beata , Data Przemysław 
Published: August 2023

AbstractFour A‐π‐D‐π‐A type small organic molecules with 1,8‐naphthalimide motifs were successfully synthesised. The designed compounds are built of two 1,8‐naphthalimide units linked via ethynyl π‐linkages with selected functionalised donor motifs i. e. 2,2’‐bithiophene, fluorene, phenothiazine and carbazole derivative. The synthesis based on Sonogashira cross‐coupling allowed us to obtain the presented dyes with good yields. The resulting symmetrical small molecules’ optical, electrochemical and thermal properties were thoroughly investigated, and their potential applicability for the OLED devices was demonstrated. In addition, the relationship between molecular structure and properties was considered by employing experimental and theoretical studies. As a result of using various donor groups, it was possible to achieve efficient electroluminescence in the range from green (DEV4) to orange‐red light (DEV3) with a maximum luminance of 3 820 cd/m2 for DEV4. Upon the insertion of an acetylene linker to the designed molecules, the free rotation of D and A fragments, and hence the effective π‐electron communication within the entire molecule, is possible, which was confirmed by DFT studies. The obtained dyes are characterised by high thermal stability, reversible oxidation‐reduction process, satisfactory optoelectronic properties and good solubility in organic solvents, which is advisable for the application in small molecular organic light‐emitting diodes (SM‐OLEDs) technology.
The Different Types of Noise and How They Effect Data Analysis
Authors: Bunde Armin 
Published: August 2023

AbstractRandom (noisy) processes can be characterized by the way consecutive data are correlated. The data can be uncorrelated (white noise), short‐range correlated (often called red noise), or long‐range correlated (sometimes called pink noise). Here we describe the properties and applications of these different kinds of noise. We discuss, how they influence (i) the diffusion process, (ii) the occurrence of rare extreme events and (iii) the detection of an external trend that is superimposed on the noise; (ii) and (iii) are particularly relevant in the context of detecting anthropogenic global warming by data analysis.
Do Naturally Modified Nucleotides Contribute to Stabilizing Complexes between Ribosomes and Small Molecules? A Case Study with the Antitumor Drug Homoharringtonine
Authors: Pietra Francesco 
Published: August 2023

AbstractModified nucleotides are ubiquitous with RNAs, also in contact with drugs that target the ribosome. Whether this represents a stabilization of the drug‐ribosome complex, thus affecting the drug's affinity and possibly also intrinsic efficacy, remains an open question, however. The challenge of answering this question has been taken here with the only human‐ribosome‐targeting small‐molecule currently in clinical use, the antitumor plant alkaloid homoharringtonine (HHT). The approach consisted in dissecting HHT‐nucleotide interaction energies from QM‐MM simulations in explicit water. What emerged is a network of mostly weak interactions of the large, branched HHT with standard nucleotides and a single modified nucleotide, out of the four ones present at PCT's A site. This is unlike the case of the small, compact marine antitumor alkaloid agelastatin A, which displays only a few, albeit strong, interactions with site‐A ribosome nucleotides. This should aid tailoring drugs targeting the ribosome.
A Fault‐tolerant model for tuple space coordination in distributed environments
Authors: Kirti Medha , Maurya Ashish Kumar , Yadav Rama Shankar 
Published: August 2023

SummaryIn distributed systems, tuple space is one of the coordination models that significantly maximizes system performance against failure due to its space and time decoupling features. With the growing popularity of distributed computing and increasing complexity in the network, host and link failure occurs frequently, resulting in poor system performance. This article proposes a fault‐tolerant model named Tuple Space Replication (TSR) for tuple space coordination in distributed environments. The model introduces a multi‐agent system that consists of multiple hosts. Each host in a multi‐agent system comprises an agent space with a tuple space for coordination. In this model, we introduce three novel fault‐tolerant algorithms for tuple space primitives to provide coordination among hosts with tolerance to multiple links and hosts failure. The first algorithm is given for out() operation to insert tuples in the tuple space. The second algorithm is presented for rdp() operation to read any tuple from the tuple space. The third algorithm is given for inp() operation to delete or withdraw tuples from the tuple space. These algorithms use less number of messages to ensure consistency in the system. The message complexity of the proposed algorithms is analyzed and found O(n) for out(), O(1) for rdp(), and O(n) for inp() operations which is comparable and better than existing works, where n is the number of hosts. The testbed experiment reveals that the proposed TSR model gives performance improvement up to 88%, 70.94%, and 63.80% for out(), rdp(), and inp() operations compared to existing models such as FT‐SHE, LBTS, DEPSPACE, and E‐DEPSPACE.
Gel Polymer Electrolytes with Talc as a Natural Mineral Filler and a Biodegradable Polymer Matrix in Sodium‐Ion Batteries
Authors: Swiderska‐Mocek Agnieszka , Karczewska Izabela , Gabryelczyk Agnieszka , Popławski Mikołaj , Czarnecka‐Komorowska Dorota 
Published: August 2023

AbstractA gel polymer electrolyte based on poly(vinyl alcohol) (PVA) is used in sodium‐ion batteries (SIBs). The use of biodegradable and water‐soluble polymer potentially reduces the negative environmental impact. The other components include sodium salt (NaPF6), sulfolane (TMS) as a plasticizer and talc. For the first time, natural and abundant talc has been used as an inert filler in a gel polymer electrolyte. The best results were obtained for moderate amounts of filler (1 and 3 wt%). Then, an increase in the conductivity, transference numbers, and thermal stability of the membranes was observed. Moreover, the presence of talc had a positive effect on the cyclability of the hard carbon electrode. The discharge capacity after 50 cycles of HC|1 % T_TMS|Na and HC|3 % T_TMS|Na was 243 and 225 mAh g−1, respectively. The use of talc in gel polymer electrolytes containing sodium ions improves the safety and efficiency of SIBs.
Gold‐Catalyzed Asymmetric Transformation of Hydroxylated Propargylic Esters
Authors: Quintanilla Carlos D. , Zhao Ke , Zhang Liming 
Published: August 2023

AbstractBy combining tandem asymmetric gold catalysis and subsequent stereoconvergent hydrolysis of enol ester in a one‐pot process, hydroxylated propargylic esters are converted into chiral β‐oxygenated ketones with mostly good enantiomeric ratios and in largely good to excellent yields. The product chiral center is formed via stereoselective cyclization of a hydroxylated allenyl ester intermediate, which is enabled by asymmetric gold‐ligand cooperation.
Synthesis, Types, and Applications of Zeolite Capsule Catalysts
Authors: Zhang Zhuang , Sun Yuewen , Zhang Hongxiang , Wei Lihong 
Published: August 2023

AbstractCapsule catalysts offer a unique spatial confinement effect, which effectively minimizes byproduct formation, enhances catalyst life, and promotes tandem reactions, thus reducing energy, time, and raw material consumption. This review presents an overview of recent advances and research progress in capsule catalysts, highlighting major breakthroughs in preparation strategies over the past decade. Innovative synthesis methods are discussed based on synthesis principles, difficulty, and effectiveness, along with an analysis of growth mechanisms and the advantages and disadvantages of zeolite shells. Application status of capsule catalysts in high‐value hydrocarbon synthesis from syngas, low‐carbon alkane dehydroaromatization, and CO2 hydrogenation reactions is explored. Finally, challenges and future prospects for scientific research and industrial applications of capsule catalysts are addressed.
Malignant pleural effusion and pericardial effusion, an unusual presentation of metastatic adenoid cystic carcinoma of the floor of mouth: A case report with cyto‐histopathological correlation
Authors: Lin Chiao , Nandakumar Lakshmy 
Published: August 2023

AbstractAdenoid cystic carcinoma (ACC) is an uncommon tumour that represents 5%–10% of salivary gland tumours and 1% of all head and neck malignancies. It is characterised by a protracted clinical course with late metastasis and poor long‐term prognosis. We report the case of a 38‐year‐old woman presenting with pulmonary and pleural metastases, on the background of ACC of the floor of mouth, which had been treated 4 years ago with surgical excision and radiotherapy. Cytological evaluation of the pleural effusion showed exfoliated ACC tumour cells. Despite palliative chemotherapy, the patient developed disease progression including metastatic spread to the pericardium, and died of disease within a year. This case illustrates an unusual presentation of ACC and highlights the importance of considering this entity when encountering a basaloid neoplasm in extra‐salivary locations.
Diabetes and incidence of breast cancer and its molecular subtypes: A systematic review and meta‐analysis
Authors: Xiong Fanxiu , Dai Qichen , Zhang Sihan , Bent Stephen , Tahir Peggy , Van Blarigan Erin L. , Kenfield Stacey A. , Chan June M. , Schmajuk Gabriela , Graff Rebecca E. 
Published: August 2023

AbstractDiabetes mellitus (DM) has been proposed to be positively associated with breast cancer (BCa) risk due to shared risk factors, metabolic dysfunction, and the use of antidiabetic medications. We conducted a systematic review and meta‐analysis to evaluate the association between DM and BCa risk. We searched PubMed, Embase, and Web of Science for cohort and case‐control studies assessing the association between DM and BCa published before 10 December 2021. Two reviewers independently screened the studies for inclusion, abstracted article data, and rated study quality. Random effects models were used to estimate summary risk ratios (RRs) and 95% confidence intervals (CIs). From 8396 articles identified in the initial search, 70 independent studies were included in the meta‐analysis. DM was associated with an overall increased risk of BCa (RR = 1.20, 95% CI: 1.11–1.29). The 24 case‐control studies demonstrated a stronger association (RR = 1.26, 95% CI: 1.13–1.40) than the 46 cohort studies (RR = 1.15, 95% CI: 1.05–1.27). Studies reporting risk by menopausal status found that postmenopausal women had an elevated risk of developing BCa (RR = 1.12, 95% CI: 1.07–1.17). No association between DM and BCa risk was observed among premenopausal women (RR = 0.95, 95% CI: 0.85–1.05). In addition, DM was associated with significantly increased risks of oestrogen receptor (ER)+ (RR = 1.09, 95% CI: 1.00–1.20), ER‐ (RR = 1.16, 95% CI: 1.04–1.30), and triple negative BCa (RR = 1.41, 95% CI: 1.01–1.96). The association estimate for human epidermal growth factor 2‐positive BCa was also positive (RR = 1.21, 95% CI: 0.52–2.82), but the CI was wide and crossed the null. Our meta‐analysis confirms a modest positive association between DM and BCa risk. In addition, our results suggest that the association between DM and BCa may be modified by menopausal status, and that DM may be differentially associated with BCa subtypes defined by receptor status. Additional studies are warranted to investigate the mechanisms underlying these associations and any influence of DM on BCa receptor expression.
Validation of the youth‐nine item avoidant/restrictive food intake disorder screen
Authors: Billman Miller Marley G. , Zickgraf Hana F. , Murray Helen Burton , Essayli Jamal H. , Lane‐Loney Susan E. 
Published: August 2023

AbstractObjectiveThis study assessed the factorial, divergent, and criterion‐related validity of the Youth‐Nine Item Avoidant/Restrictive Food Intake Disorder (ARFID) Screen (Y‐NIAS) in a paediatric clinical sample at initial evaluation for an eating disorder (ED).MethodParticipants included 310 patients (82.9% female, 77.4% White, Age M = 14.65) from a tertiary ED clinic. Confirmatory factor analysis (CFA) evaluated the three‐factor of the Y‐NIAS. One‐way analysis of variance compared Y‐NIAS scores across diagnoses. A receiver operating curve analysis assessed the ability of each subscale to identify ARFID presentations from the full sample. Two logistic regressions assessed the criterion‐related validity of the obtained Y‐NIAS cut‐scores.ResultsCFA supported the original three‐factor structure of the Y‐NIAS. Clinically‐elevated scores were observed in all diagnostic groups except for binge‐eating disorder. Subscales were unable to discriminate ARFID cases from other ED diagnoses. Cut scores were identified for picky eating subscale (10) and Fear subscale (9), but not for Appetite subscale. In combination with the ED Examination Questionnaire (EDE‐Q), classification accuracy was moderate for ARFID (62.7%) and other EDs (89.4%).DiscussionThe Y‐NIAS demonstrated excellent factorial validity and internal consistency. Findings were mixed regarding the utility of the Y‐NIAS for identifying clinically‐significant ARFID presentations from other ED diagnoses.
Aeolian dust accretion outpaces erosion in the formation of Mediterranean alpine soils. New evidence from the periglacial zone of Mount Olympus, Greece
Authors: Styllas Michael , Pennos Christos , Persoiu Aurel , Godelitsas Athanasios , Papadopoulou Lambrini , Aidona Elina , Kantiranis Nikolaos , Ducea Mihai N. , Ghilardi Matthieu , Demory Francois 
Published: August 2023

AbstractSoil formation in Mediterranean periglacial karst landscapes remains poorly understood as the interplay between local and allochthonous sources of parent materials, and mineral alteration and pedogenesis, as dominant post‐depositional processes, depends on a variety of climatic and environmental factors. Herein, we investigate the balance between erosion and aeolian dust accretion in the formation of an alpine soil profile in the periglacial zone of Mount Olympus in Greece. We applied a wide range of analytical methods to 23 samples, from a soil profile developed in a glaciokarstic plateau, from colluvial sediment horizons interbedded in postglacial scree slopes of different maturity and formation age and from modern Sahara dust samples deposited on the snowpack. Colluvial sediment horizons exhibit high concentrations of carbonate gravel and calcite‐rich sand and represent the local erosion products. The soil B horizon developed on the glaciokarstic plateau, contains high amounts of fine earth and is rich in quartz, mica, plagioclase, clays and Fe–Ti oxides. Based on physical and textural characteristics, the soil profile is partitioned in a surficial weathered Bw and an illuvial Bt horizon that overlies the local regolith composed of fragmented glacial till and slope wash deposits. Radiogenic isotope systematics, textural and mineralogical analysis show that the contribution of aeolian (Sahara and locally sourced) dust to the development of the soil B horizon ranges between 50% and 65%. Cryoturbation results in fine earth translocation from Bw to the Bt horizon, whereas weak pedogenetic modifications of detrital (aeolian and bedrock‐derived) minerals result in magnetic mineral weathering and secondary clay formation. Our findings reveal that aeolian dust accretion from Saharan and lcal sources is the dominant process in providing alpine soil parent material and that cryoturbation, weak pedogenesis and clay mineral alteration occur within the Mediterranean periglacial zone of Mount Olympus.
Recent advances on the effect of nut consumption on cognitive improvement
Authors: Wu Weijie , Niu Ben , Peng Liang , Chen Qi , Chen Huizhi , Chen Hangjun , Xia Wei , Jin Long , Simal‐Gandara Jesus , Gao Haiyan 
Published: August 2023

AbstractCognitive disorders, including dementia, Parkinson's and Alzheimer's disease, pose significant public health issues. Preventing/delaying their onset is essential as effective medical treatments are unavailable. Nuts contain bioactive compounds, including fatty acids, macronutrients such as proteins and dietary fibers, micronutrients, and polyphenols; these act synergistically preventing age‐related diseases. Epidemiological investigations have established that high nut consumption reduces cognitive impairment risk, suggesting it is useful for cognitively impaired individuals; however, clinical data on the effects of nut consumption on cognitive function are lacking. This review summarized nut consumption effects on oxidative stress, inflammatory response, and gut microbiota. Nuts reduce oxidative stress; their active substances, including glansreginin A, proanthocyanidins, quercetin, and nut oil, have significant anti‐inflammatory effects. Furthermore, they comprise complex mixtures, which synergistically induce beneficial changes in the intestinal microbial community.
Evaluating the effect of food components on the digestion of dietary nucleic acids in human gastric juice in vitro
Authors: Zhang Yanfang , Dong Jingyi , Chen Jingxian , Pan Xiaoming 
Published: August 2023

AbstractNucleic acids (NAs) were recently shown to be digested by pepsin in vitro; however, NAs digestion in human gastric juice in vivo is more complicated because of the complex gastric environment and ingestion of other food components. The purpose of this study was to investigate the digestibility of NAs in real human gastric juices after ingestion of other food components. As a result, DNA digestion was not affected when carbohydrates, proteins, and metal elements were ingested within the recommended dietary intake levels. Separately, protein exerted an inhibitory effect on DNA digestion when the mass ratio of protein:DNA was greater than 40:1. DNA exists in the nucleoprotein, which is closer to the state of DNA in real food, and was digested efficiently in human gastric juice. Meanwhile, DNA digestion was rarely affected even when the concentrations of monovalent ion (Na+) and divalent ions (Mg2+) were as high as 500 and 100 mM, respectively, and high concentration of Mg2+ ranged from 20 to 100 mM accelerated the digestion. In particular, short‐stranded DNA (<100 nt) and miRNAs (19 ~ 25 nt) were not obviously degraded in human gastric juice. In conclusion, dietary NAs were digested efficiently and were not affected by other food components in human gastric juice, which may facilitate further digestion and utilization of DNA in the intestinal tract.
Sequential Itô–Taylor expansions and characteristic functions of stochastic volatility models
Authors: Ding Kailin , Cui Zhenyu , Liu Yanchu 
Published: August 2023

AbstractThis study proposes a new approach to derive the characteristic function of a general stochastic volatility model by sequentially utilizing the Itô–Taylor expansions. In particular, our method applies to non‐affine stochastic volatility models with jumps, for which the corresponding characteristic functions do not have closed‐form expressions. Numerically inverting these characteristic functions can yield accurate probability density functions of stochastic volatility models to serve for various pricing and hedging purposes in quantitative finance. The proposed sequential Itô–Taylor expansion allows us to handle derivatives with medium to long maturities. Numerical experiments illustrate the accuracy and effectiveness of our approach.
Constitutional balanced translocations involving SMARCB1: A rare cause of rhabdoid tumor predisposition syndrome
Authors: Blackburn Patrick R. , McGee Rose B. , Mostafavi Roya , Carroll Andrew J. , Mikhail Fady M. , Armstrong Gregory T. , Furtado Larissa V. , Chiang Jason , Wheeler David A. , Carey Steven S. , Nichols Kim E. , Upadhyaya Santhosh A. 
Published: August 2023

AbstractRhabdoid Tumor Predisposition Syndrome 1 (RTPS1) confers an increased risk of developing rhabdoid tumors and is caused by germline mutations in SMARCB1. RTPS1 should be evaluated in all individuals with rhabdoid tumor and is more likely in those with a young age at presentation (occasionally congenital presentation), multiple primary tumors, or a family history of rhabdoid tumor or RTPS1. Proband genetic testing is the standard method for diagnosing RTPS1. Most known RTPS1‐related SMARCB1 gene mutations are copy number variants (CNVs) or single nucleotide variants/indels, but structural variant analysis (SVA) is not usually included in the molecular evaluation. Here, we report two children with RTPS1 presenting with atypical teratoid/rhabdoid tumor (ATRT) who had constitutional testing showing balanced chromosome translocations involving SMARCB1. Patient 1 is a 23‐year‐old female diagnosed with pineal region ATRT at 7 months who was found to have a de novo, constitutional t(16;22)(p13.3;q11.2). Patient 2 is a 24‐month‐old male diagnosed with a posterior fossa ATRT at 14 months, with subsequent testing showing a constitutional t(5;22)(q14.1;q11.23). These structural rearrangements have not been previously reported in RTPS1. While rare, these cases suggest that structural variants should be considered in the evaluation of children with rhabdoid tumors to provide more accurate genetic counseling on the risks of developing tumors, the need for surveillance, and the risks of passing the disorder on to future children. Further research is needed to understand the prevalence, clinical features, and tumor risks associated with RTPS1‐related constitutional balanced translocations.
Exploring the relationship between bird diversity and anxiety and mood disorder hospitalisation rates
Authors: Buxton Rachel T. , Pearson Amber L. , Lin Hsien‐Yung , Sanciangco Jonnell C. , Bennett Joseph R. 
Published: August 2023

AbstractNatural environments provide a myriad of health benefits, yet the role of species diversity within these spaces remains underexplored. Bird diversity may yield mental health benefits for humans, through birdsong or feelings of connection to nature. In an initial effort to establish whether bird diversity may be linked with human health in a US context and to test the consistency in such trends from year to year, we combine widely available community (aka citizen) science data (eBird) estimating bird diversity across the state of Michigan with anxiety/mood disorder hospitalisation records (2008–18). We found a negative, significant association between bird species diversity and anxiety/mood disorder hospitalisations (β = −0.36, 95% CI = −0.69 to −0.04). The relationship between bird diversity and hospitalisations found at this scale is significant, given the potential for biodiversity to affect severe mental health outcomes. Thus, these initial findings should be further explored in studies with finer resolution of exposure to bird species and longitudinal or experimental designs that account for other demographic characteristics, risk factors and other neighbourhood features. If future studies confirm these findings, there are important implications for urban greening efforts, some of which are explicitly focused on increasing bird habitat.