bluuebunny/crossref_metadata_2025_split huggingface dataset:
Severity of All-Terrain Vehicle–Related Injuries by Age in Canada, 2002-2019
Authors: MacDougall William , Jiang Xuejing , Sobhan Shamsia , Balshaw Robert , Haas Barbara , Moore Lynne , Yanchar Natalie , McGavock Jonathan 
Published: May 2023

ImportanceRates of pediatric hospitalizations following an injury while riding an all-terrain vehicle (ATV) are increasing. Few studies have compared the rates of severe injuries among children, adolescents, and adults.ObjectivesTo investigate whether younger ATV riders are at risk for more severe ATV-related injuries.Design, Setting, and ParticipantsThis cross-sectional study was conducted using administrative data from hospitals in 9 provinces in Canada. Participants included patients admitted to hospitals with ATV-related injuries between 2002 and 2019. Statistical analysis was performed from June 2020 to September 2021.ExposuresThe primary exposure was age younger than 16 years. Comparison groups were youths aged 16 to 20 years and adults aged 21 years and older.Main Outcomes and MeasuresThe main outcomes of interest were death, spinal cord injury, and an Injury Severity Score (ISS) greater than 25. Secondary outcomes were less severe injuries, including head injuries, crush type injuries, and fractures.ResultsAmong 52 745 patients with complete data, 15% were youths younger than 16 years, 13% were youths aged 16 to 20 years, 82% were male, and 47% lived in rural areas. After adjusting for covariates, the odds of dying were higher among youths aged 16 to 20 years (adjusted odds ratio [aOR], 1.64; 95% CI, 1.04-2.60) compared with those younger than 16 years. Youths aged 16 to 20 years also had higher odds of spinal cord injury (aOR, 2.72; 95% CI, 1.80-4.20) and an injury severity score greater than 25 (aOR, 1.63; 95% CI, 1.36-1.96) compared with youths 16 years of age or less. Sex-specific analyses revealed these associations were greater for male youths aged 16 to 20 years (spinal cord injury: aOR, 3.81; 95% CI, 1.38-11.10, and dying in a hospital: aOR, 4.37; 95% CI, 1.19-21.02) than female youths aged 16 to 20 years.Conclusions and RelevanceIn this cross-sectional study of patients hospitalized for ATV injuries in Canada, youths aged 16 to 20 years and adults aged 21 years and older were at an increased risk of death and severe injuries compared with youths younger than 16 years. The increased risk of death and severe injuries was most evident among male patients.
Memory, metamemory, and false memory for features of the Apple logo
Authors: Whatley Mary C. , Schwartz Shawn T. , Block Jessica B. , Castel Alan D. 
Published: May 2023

AbstractOur memory for common, easily recognizable logos, like the Apple logo, is surprisingly poor because of attentional saturation, where we stop attending to details of frequently encountered objects. This lack of attention to details may leave us susceptible to misinformation effects. Across four experiments, we tested recognition memory for the Apple logo after incidentally encoding an accurate or altered version of the logo (Experiments 1–3), or after no incidental encounter of the logo prior to the surprise test (Experiment 4). Additionally, participants rated how much they liked the logo as a measure of processing fluency. Results demonstrated that incidentally viewing an altered version of the Apple logo can disrupt subsequent recognition of the correct logo, but this effect may diminish following a short delay. Considering our frequent exposure to everyday stimuli, we show conditions in which memory for a ubiquitous stimulus can be disrupted when incidentally presented with inaccurate information.
Self‐Assembled Artificial Light‐Harvesting System Constructed Using Electrostatic Interactions in Aqueous Solution for the Sensing of Heavy Metal Cations
Authors: Li Meng , Shi Quanyu , Song Ningxin , Chen Zhijun , Wang Lidong , James Tony D. 
Published: May 2023

AbstractA supramolecular artificial light‐harvesting system (LHS) is successfully constructed in an aqueous environment using carbon dots (CDs) andα,β,γ,δ‐Tetrakis(1‐methylpyridinium‐4‐yl) porphyrin p‐Toluenesulfonate (TMPyP) via electrostatic interactions. Specifically, the CDs act as a donor, and TMPyP, which is loaded to the surface of the CDs, acts as an acceptor for the LHS. Energy transfer occurs from the CDs to the TMPyP in the assembled CDs‐TMPyP upon UV excitation. To demonstrate the applicability, the CDs‐TMPyP system is used as a sensor for Hg(II) in an aqueous solution. Subsequently, a functional material suitable for the detection and removal of Hg(II) is fabricated by integrating the CDs‐TMPyP into a polymer network.
A Highly Active Hydroformylation Catalyst Using a Self‐Assembling Bis‐N‐Pyrrolyl Phosphine Ligand
Authors: Bauer Felix , Dierenbach Niklas , Breit Bernhard 
Published: May 2023

AbstractHerein we report an improved self‐assembling phosphorus ligand based on hydrogen bonding between pyridone/hydroxypyridine in the ligand backbone. The N‐pyrrolyl substituents significantly improve the π‐backbonding properties of the ligand. Rhodium, iridium and platinum complexes of the ligand were prepared and analyzed by NMR spectroscopy and x‐ray crystal structure analysis. A catalyst based on this ligand showed very high catalytic activity and linear regioselectivity in rhodium‐catalyzed hydroformylation of 1‐octene. The same ligand was applied in linear regioselective iridium‐catalyzed hydroformylation of 1‐octene.
Assessment of two in‐situ and ex‐situ methods for silver/graphene oxide‐grafted cotton fabrics fabrication and antibacterial activity enhancement by hydrophobic modification with stearic acid
Authors: Huong Quach Thi Thanh , Nam Nguyen Thanh Hoai , Tinh Ninh Thi , Hai Nguyen Duy , An Hoang , Vy Nguyen Pham Tuong , Han Tran My , Khanh Tran Nhat , Nhi Tran Le Hoai , Hieu Nguyen Huu 
Published: May 2023

AbstractThe increase in the number of infectious diseases has exerted many negative consequences on human health. In this study, the antibacterial cotton fabric was fabricated for application in antibacterial products, contributing to the prevention of infectious diseases for humans. Particularly, ex‐situ and in‐situ dip‐coating techniques were compared and utilized for the fabrication of the antibacterial cotton fabric. Besides, the effects of the concentrations of precursors, including graphene oxide (GO), silver nanoparticles (AgNPs), silver/graphene oxide nanocomposite (Ag/GO), and dip‐coating times were evaluated to determine the most appropriate preparation conditions. Therewithal, the resulting cotton fabric was modified with stearic acid (SA) to enhance the hydrophobicity, in which the concentration of the SA was also assessed. Additionally, the antibacterial performance of the prepared material was investigated against Gram‐negativePseudomonas aeruginosaand Gram‐positiveStaphylococcus aureus. Different analytical techniques such as scanning electron microscope, contact angle measurement, and color stability were also utilized for the comparison between different cotton fabrics. According to the obtained results, the dip‐coated in‐situ Ag/GO (in‐situ‐Ag/GO/cotton) fabrics showed better antibacterial performance than that of dip‐coated ex‐situ Ag/GO (ex‐situ‐Ag/GO/cotton) ones, which can be attributed to the even distribution of Ag/GO nanocomposite on the fabric prepared by the in‐situ methods. According to the aforementioned results, the resulting antibacterial cotton fabric can be considered a promising material for the production of antibacterial face masks and protective clothing, which can be utilized in hospitals, textile industries, or the manufacture of sport gears.
Silver‐Catalyzed Synthesis of Benzyl Ethers via Alkoxylation of Benzylic C(sp3)−H Bonds
Authors: Huang Peng , Zhang Guang'an , Wang Zechao , Wu Junliang 
Published: May 2023

AbstractAlkoxylation of benzylic C(sp3)−H bonds has become one of the most important tools for the construction of benzyl ethers from feedstock chemicals. Herein, we reported a silver catalyzed alkoxylation of benzylic C(sp3)−H bonds employing potassium persulfate as an oxidant at room temperature. This strategy showed good functional‐group tolerance, site selectivity, and chemoselectivity. The reaction proceeded smoothly in the presence of various primary, secondary, and tertiary alcohol nucleophiles, affording corresponding benzyl ethers. Combined experimental studies provided mechanistic insights into the possible radical pathways. Furthermore, a possible mechanism was proposed for this method.
Synthesis, antioxidant effectiveness, and docking study of new benzothiazolyl‐chromenone‐based fluorophores
Authors: Hossan Aisha , Al‐nami Samar Y. 
Published: May 2023

AbstractAs chromenones demonstrate significant push–pull fluorescence effects on the development and description of novel push–pull fluorescent compounds based on chromenone with exceptional molar extinction coefficients, benzothiazolyl‐chromenone‐based fluorophores were created by refluxing ethanol/piperidine over Knoevenagel's condensation. Many spectral methods, including 1H‐NMR, FT‐IR analysis, and (C, H, N) analysis, were used to demonstrate the molecular structures of the synthesized benzothiazolyl‐chromenone‐based fluorophores. The synthesized fluorophore UV–vis absorption and emission spectra showed significant extinction coefficients, which were observed to be influenced by the substituted benzothiazole bridge in conjugation with the alkoxy donor moiety. It was discovered that the alkoxyl group‐bonded substituents had an effect on the maximum absorbance wavelength. The benzothiazolyl‐chromenone hybrid achieved antioxidant efficacy that compared favourably with commonly used medications [butylated hydroxytoluene (BHT) and vitamin C]. In contrast with the other hybrids, hybrid 3c, which has a hexyloxy tail, made good claims about its suitable action towards vitamins and reference medications. Additionally, the synthesized benzothiazolyl‐chromenone‐based hybrids showed marked coordination with antioxidant efficacy when docked studies of the hybrids towards the chosen 3NM8 protein were conducted.
One‐pot synthesis of unsymmetrical 1,3‐butadiyne derivatives
Authors: Zhao Zhicai 
Published: May 2023

AbstractAn efficient co‐operative Ni/Cu system for Cadiot–Chodkiewicz coupling utilizes CaC2 as the alkyne source. The advantage of this cross‐coupling reaction lies in the low cost of using cheap and readily available raw materials and the simplicity of operation. A series of functionalized diaryl, aryl‐alkyl, and aryl‐heteroaryl 1,3‐diynes are obtained in moderate to high yields.
Two New Cembranoids from the Chinese Soft Coral Sarcophyton boettgeri**
Authors: Yu Jia‐Dong , Su Ming‐Zhi , Gu Yu‐Cheng , Yu Dan‐Dan , Yao Li‐Gong , Shen Shou‐Mao , Guo Yue‐Wei , Wang Hong 
Published: May 2023

AbstractTwo new cembranoids, namely sarcoboettgerols D and E, together with four known related ones, have been isolated from the soft coral Sarcophyton boettgeri collected from Weizhou Island in the South China Sea. Their structures including absolute configurations were elucidated by extensive spectroscopic analysis, quantum mechanical nuclear magnetic resonance methods, time‐dependent density functional theory‐electronic circular dichroism calculations, as well as comparison with the reported data in the literature. A plausible biogenetic relationship of four cembranoids was proposed. In bioassays, sarcomililatin B exhibited cytotoxic activity against H1299 cell (IC50=35.0 μM), whereas sarcomililatin B and sarcomililatin A displayed moderate antibacterial activities (MIC 17.4–34.8 μg/mL).
Long‐term survival in a dog with probable thyroid storm
Authors: Beverly Jeffrey , Pigott Armi , Puzio Claire E. , Rivera Meghan 
Published: May 2023

Key Clinical MessageThyroid storm is a rare, life‐threatening endocrine emergency that may occur in dogs. With rapid identification and early aggressive therapy, long‐term survival is possible.AbstractThe aim of this paper was to describe the successful emergency management and long‐term survival of a dog with probable thyroid storm. We present proposed guidelines for the characterization of thyroid storm in dogs, and treatment considerations as utilized for this patient. A 6‐year‐old female spayed German Shepherd Dog was presented to a multispecialty center for radiation planning and treatment of a previously diagnosed nonresectable functional thyroid carcinoma. Recovering from anesthesia, the patient developed clinical features that would qualify as thyroid storm using human metrics. The patient improved with aggressive treatment of thyroid storm, extrapolating from human and feline recommendations. This is the first known report of long‐term survival in a canine with suspected thyroid storm. The crisis was effectively identified and emergently treated.
Negative pressure pulmonary edema due to upper airway obstruction after general anesthesia in a patient with Parkinson's disease: A case report
Authors: Hasegawa Ayaka , Niimi Naoko , Mitaka Chieko , Hayashida Masakazu 
Published: May 2023

Key Clinical MessageIn a patient with Parkinson's disease (PD) who underwent spine surgery 13 h after the last anti‐Parkinson medications, negative pressure pulmonary edema from upper airway obstruction developed immediately after extubation. Although oxygenation improved with high‐flow nasal cannula therapy, such complications might develop due to abrupt discontinuation of medication for PD.
Post‐COVID‐19 syndrome mimicking cholangiocarcinoma: A case report
Authors: Khonsari Mahmoodreza , Boostani Kamal , Farnood Farahnoosh 
Published: May 2023

Key Clinical MessageThe differential diagnosis of post‐COVID‐19 syndrome is important in patients with symptoms of biliary obstruction. This patient had severe COVID‐19 who underwent ERCP and mimicked cholangiocarcinoma.AbstractPatients with severe coronavirus disease 2019 (COVID‐19) manifest liver injuries with pathological changes because of lowered blood oxygen saturation, cardiac malfunction, hepatotoxic drugs during treatment, and cellular injury. This paper reports a patient with a history of severe COVID‐19 who mimics cholangiocarcinoma after undergoing endoscopic retrograde cholangiopancreatography (ERCP). It was shown that differential diagnosis of post‐COVID‐19 syndrome is greatly important mostly in patients with symptoms of biliary obstruction.
Rare forearm intramuscular myxoma: A case report
Authors: Pirmohamadi Hosein , Begloo Mahmood Jafar , Rahimi Mohsen , Akbaribazm Mohsen 
Published: May 2023

Key Clinical MessageIntramuscular myxoma (IMM) is a benign soft tissue tumor of mesenchymal origin that occurs mainly in skeletal muscles which can be removed through surgery after diagnosis.AbstractIntramuscular myxoma (IMM) is a benign soft tissue tumor of mesenchymal origin that typically occurs in skeletal muscles. Its diagnosis is based on magnetic resonance imaging (MRI) and histopathologic evaluation of the lesion. In our report, we describe the case of a 60‐year‐old female with an IMM in the supinator muscle of the right forearm, which was confirmed by MRI and histopathologic examination. Following surgery to remove the mass, a follow‐up confirmed the patient's recovery and the absence of movement limitations in the elbow joint.
Direct Valorization of Recycled Palladium as Heterogeneous Catalysts for Total Oxidation of Methane
Authors: y Morales Michaël Martin Romo , Brunet‐Manquat Anthony , Dib Hadi , Rousset Jean‐Luc , Morfin Franck , Burel Laurence , Bourgeois Damien , Kaper Helena 
Published: May 2023

AbstractElectronic waste as an alternative source of palladium is used for the preparation of heterogeneous catalysts for methane oxidation. The strategy developed in this paper involves two steps: optimization of the leaching protocol to recover the Pd from the waste, and development of a suitable impregnation protocol directly from the leachate, which is a strongly acidic solution. The precipitation‐deposition technique is particularly suitable for the preparation of catalysts from acidic media. The impact of Ba, Bi, and Ag impurities on the catalytic performance is studied on model catalysts. The presence of these elements and their impact on the catalytic properties are analyzed and discussed using X‐ray diffraction, nitrogen physisorption, scanning and transmission electron microscopy. Through variation of the pH, the impurities co‐deposited with Pd can be limited and the catalytic performance of catalysts derived from real waste can be greatly enhanced.
A Sustainable and Catalytic Synthesis of Dibenzosuberone
Authors: Nori Valeria , Della Penna Francesca , Cocco Emanuele , Mantegazza Simone , Razzetti Gabriele , Quattrocchi Giuseppe , Pesciaioli Fabio , Carlone Armando 
Published: May 2023

AbstractDibenzosuberone (DBS) is a key intermediate for the synthesis of relevant active pharmaceutical ingredients (APIs) for the treatment of several diseases related to the central nervous system. Herein, the design and development of a milder and greener approach to improve the well‐established methodology for the synthesis of DBS limiting waste production via the use of immobilized catalysts are presented.
Preparation of Ca(OH)2 nanoparticles by impinging stream reaction precipitation method
Authors: Zhang Jianwei , Zhang Jin , Dong Xin , Feng Ying , Niu Juchao 
Published: May 2023

AbstractIn this paper, Ca(OH)2 nanoparticles are prepared by impinging stream co‐precipitation method. The process of preparing nanoparticles by impinging stream is optimized. The influence of process variable, such as dispersant type, dispersant dosage, circulating flow rate, reactant concentration ratio of OH− and Ca2+, reaction temperature and circulation time, on the particle size of Ca(OH)2 nanoparticle are investigated. The results show that the concentration ratio of reactants has a significant effect on the size of Ca(OH)2 nanoparticles. The optimal process conditions are obtained by single factor experiment, PEG6000, 3.3% dispersant dosage, Q = 1000 L · h−1, C = 1.88, T = 46.68°C and t = 60 min. The average particle size of Ca(OH)2 nanoparticles prepared under these conditions is 107.67 nm. According to the microstructure analysis, the prepared Ca(OH)2 nanoparticles samples have high purity and a good crystal structure. The powder dispersed with a marked hexagonal crystal shape and good thermal decomposition.
Correlation between serum laminin level and prognosis of acute heart failure
Authors: Yan Xiaoyun , Ye Jiaqi , Chen Haixiao , Jiang Ying , Xie Ling , Zhang Ying , Qiang Wenhui , Cai Hongli , Zheng Koulong , Zhang Qing 
Published: May 2023

AbstractObjectiveTo investigate the correlation between serum laminin (LN) level and the prognosis of acute heart failure (AHF).MethodsA total of 199 patients with AHF treated in Nantong First People's Hospital from March 2019 to November 2021 were included in this study. The patients were divided into the event group and the non‐event group according to whether major adverse cardiovascular events (MACEs) occurred during hospitalization. We collected the baseline data of all patients and their LN levels were measured. The receiver operating characteristic (ROC) curve was used to analyze the predictive value of LN for the occurrence of MACE in AHF patients during hospitalization. Multivariate Logistic regression analysis was used to screen the independent factors associated with the occurrence of MACE in patients with AHF.ResultsAmong 199 patients with AHF, 43 were in the event group and 156 were in the non‐event group. The area under ROC curve of LN to predict MACE in AHF patients during hospitalization was 0.8144, 95% confidence interval (CI): 0.7433–0.8855, p < .0001, cutoff point = 77.9, specificity 58.33%, and sensitivity 88.37%. Multivariate logistic regression analysis showed that the independent factors associated with the occurrence of MACE in AHF patients were the increase of LN level (odds ratio [OR]: 1.020, 95% CI: 1.012–1.028), the decrease of ejection fraction (OR: 0.007, 95% CI: 0.000–0.362) and diastolic blood pressure (OR: 0.946, 95% CI: 0.913–0.981; p < .05).ConclusionThe increase of LN level is independently correlated with the occurrence of MACE in AHF patients during hospitalization, which has the potential to be a serological indicator for poor prognosis in patients with AHF.
Proteome profiling of salivary small extracellular vesicles in glioblastoma patients
Authors: Müller Bark Juliana , Trevisan França de Lima Lucas , Zhang Xi , Broszczak Daniel , Leo Paul J. , Jeffree Rosalind L. , Chua Benjamin , Day Bryan W. , Punyadeera Chamindie 
Published: May 2023

AbstractBackgroundExtracellular vesicles (EVs) play a critical role in intercellular communication under physiological and pathological conditions, including cancer. EVs cargo reflects their cell of origin, suggesting their utility as biomarkers. EVs are detected in several biofluids, and their ability to cross the blood–brain barrier has highlighted their potential as prognostic and diagnostic biomarkers in gliomas, including glioblastoma (GBM). Studies have demonstrated the potential clinical utility of plasma‐derived EVs in glioma. However, little is known about the clinical utility of saliva‐derived EVs in GBM.MethodsSmall EVs were isolated from whole mouth saliva of GBM patients pre‐ and postoperatively. Isolation was performed using differential centrifugation and/or ultracentrifugation. EVs were characterized by concentration, size, morphology, and EVs cell‐surface protein markers. Protein cargo in EVs was profiled using mass spectrometry.ResultsThere were no statistically significant differences in size and concentration of EVs derived from pre‐ and post GBM patients' saliva samples. A higher number of proteins were detected in preoperative samples compared to postoperative samples. The authors found four highly abundant proteins (aldolase A, 14‐3‐3 protein ε, enoyl CoA hydratase 1, and transmembrane protease serine 11B) in preoperative saliva samples from GBM patients with poor outcomes. Functional enrichment analysis of pre‐ and postoperative saliva samples showed significant enrichment of several pathways, including those related to the immune system, cell cycle and programmed cell death.ConclusionsThis study, for the first time, demonstrates the feasibility of isolating and characterizing small EVs from pre‐ and postoperative saliva samples from GBM patients. Preliminary findings encourage further large cohort validation studies on salivary small EVs to evaluate prognosis in GBM.