bluuebunny/crossref_metadata_2025_split huggingface dataset:
Las prácticas educativas de la educación física para estudiantes con necesidades educativas especiales durante la pandemia
Authors: Bennasar-García Miguel Israel , Duque Fernández Leonor Mariana , Martínez Nadal Haifa Ariana 
Published: December 2022

Introducción: El artículo analiza la situación de estudiantes con necesidades educativas especiales (NEE) quienes han limitado sus actividades físicas (AF) debido al confinamiento, situación que obliga al personal docente a diseñar nuevas prácticas educativas adaptadas a la virtualidad.
Objetivo: Analizar las prácticas educativas de la educación física (EF) para estudiantes del nivel primario con NEE durante la pandemia en la República Dominicana.
Metodología: Se utilizó el enfoque cualitativo, exploratorio de corte transversal mediante la encuesta, empleando un muestreo no probabilístico y un análisis de contenidos con redes semánticas. El estudio consta de 45 docentes, quienes proporcionaron las informaciones sobre su formación académica docente, la matrícula estudiantil asistida, las metodologías, estrategias empleadas y los recursos del proceso de enseñanza.
Resultados: Los resultados reflejan el interés del personal docente por su actividad profesional, en contraposición a la falta de apoyo de especialistas en el aula y un bajo conocimiento de la enseñanza, de las metodologías y estrategias usadas desde la virtualidad para la EF dirigida a estudiantes con NEE. Por otra parte, la mayoría de los docentes no usaron las instalaciones educativas para las actividades físicas, se utilizó la tecnología con la asistencia guiada por la familia y los adultos en el hogar, en especial con actividades físicas grupales en familia.
Conclusiones: Las actividades académicas fueron realizadas desde el hogar y han sido afectadas por la falta de condiciones idóneas para un espacio académico y la falta de recursos tecnológicos. Se debe promover la capacitación de docentes en el área de la EF para estudiantes con NEE.
Índices de obesidad en mujeres con cáncer de mama del Cauca, Colombia
Authors: Molano-Tobar Nancy Janneth , Villaquirán-Hurtado Andrés Felipe , Molano-Tobar Dolly Ximena 
Published: December 2022

Introducción: Algunos estudios permiten identificar que el cáncer de mama tiene orígenes multicausales y dentro de ellos se encuentran los trastornos derivados asociados a la grasa corporal, el objetivo fue identificar el nivel de sobrepeso u obesidad a través de índices de adiposidad en mujeres con cáncer de mama del departamento del Cauca.
Material y métodos: estudio descriptivo correlacional, con 126 mujeres diagnosticadas con cáncer de mama. Las medidas para el análisis de la grasa corporal fueron el índice de conicidad, adiposidad, volumen abdominal y la ecuación CUN BAE, IMC, perímetros de cintura y cadera, se procesó en SPSS, obteniendo medidas de tendencia central y dispersión, como el estadístico de Pearson con una significancia p < 0,05, y la curva ROC (Receiver Operating Characteristic), para determinar la sensibilidad y la especificidad de las pruebas de adiposidad, atendiendo los aspectos éticos y legales.
Resultados: el 31,78 %, de las evaluadas presentaron cáncer tipo IIb, invasivo en ganglios axilares, con una edad de la menarquia de 13,50±2,33 años. Se observó un promedio de sobrepeso según el IMC de 26,91±4,87 Kg/m2, respecto al perímetro de cintura (46.02 %) y el ICC (58.72 %) no manifestaron riesgo en estas variables; se identificaron correlaciones positivas muy altas entre el perímetro de cintura y los índices de adiposidad (R=0,992), índice de conicidad (R=0,858) y el ICC (R=0,845).
Conclusiones: se pudo establecer que un alto porcentaje de mujeres con cáncer de mama presentó sobrepeso, identificando situaciones de riesgo asociadas con la grasa acumulada alrededor de la cintura, que se relaciona con otros índices de adiposidad, la herramienta identificada como útil correspondió al índice de conicidad con significancia estadística.
Influencia de entrenamiento sensoriomotor sobre el equilibrio estático en nadadores con síndrome de Down y discapacidad intelectual
Authors: Hernández Chacón Milena , Mora Campos Andrea , Ramírez Ulloa Juan José , Víquez Ulate Fabián 
Published: December 2022

Propósito: Este estudio determinó el efecto de un programa de entrenamiento sensoriomotor sobre el equilibrio estático en nadadores con síndrome de Down (SD) y discapacidad intelectual (DI).
Metodología: Participantes: 13 personas. Instrumentos y materiales: Se utilizó el Modified Clinical Test for Sensory Integration for Balance para determinar el equilibrio y un equipo Wii Balance Board y computadora con programa de análisis del centro de gravedad. Procedimientos: se aplicó un pretest y luego se aplicó un entrenamiento neuromotor (3 sesiones semanales, de 30 minutos, durante 4 semanas), al terminar se aplicó el postest. Por tratarse de deportistas activos continuaron con su rutina sin alteraciones en la carga de entrenamiento. Se usó estadística descriptiva y ANOVA de dos vías 2X2, mediciones y grupos.
Resultados: No hubo diferencias estadísticamente significativas entre la variable mediciones (F = 0.14; p = 0.7162) ni por grupos (F = 0.2; p = 0.6659) en variable ojos abiertos estable. En la variable ojos cerrados inestable sí hubo diferencias significativas (F = 0.952; p = 0.350), por grupos (F = 6.066; p = 0.320), en la variable ojos abiertos inestable no hubo diferencias ni en mediciones (F = 0.852; p = 0.376) ni en grupos (F = 2.484; p = 0.143). En variable ojos cerrados estable no hubo diferencias en mediciones (F = 0.716; p = 0.415) ni por grupos (F = 0.801; p = 0.390). Se demostró que este entrenamiento en esa población produce mejora en la variable equilibrio ya que muestra una diferencia significativa p < 0.05 en la variable ojos abiertos inestable 0.32.
Efecto del Ejercicio en el Medio Acuático sobre la Aptitud Física en Personas con Discapacidad Intelectual: Una Revisión Sistemática
Authors: Ozols Rosales Maria Antonieta , Fonseca Jeffry Tames , Araya Maria Antonieta Corrales , Jiménez José Moncada 
Published: December 2022

Introducción: Los programas de ejercicio en el medio acuático proporcionan un ambiente motivante y divertido, en el cual las personas con discapacidad intelectual pueden realizar actividades deportivas o recreativas de manera accesible, lo que incide positivamente en la condición física.
Propósito: El objetivo de la revisión sistemática fue conocer los efectos del ejercicio acuático sobre la aptitud física en personas con discapacidad intelectual.
Metodología: Para lograr el propósito del estudio, se llevó a cabo una búsqueda de literatura en las bases de datos Sport Discus, Science Direct, Scopus y PubMed, cuyas publicaciones comprenden del 2009 al 2018; como criterios de inclusión debían especificar el tipo de ejercicio, los componentes de la carga de entrenamiento, el tipo de discapacidad que presentaban los sujetos del estudio y que la duración de la intervención fue mayor a 4 semanas.
Resultados: Solamente 5 trabajos cumplieron los criterios de selección. Aquellos en los que aplicaron intervenciones de natación y ejercicio combinado indicaron que se mejoraron elementos de la aptitud física importantes para la salud, así como el desenvolvimiento de actividades de la vida diaria. Se pudo concluir que se requieren investigaciones con mayor rigor metodológico, para clarificar el efecto del ejercicio en el medio acuático sobre los componentes de la aptitud física en personas con discapacidad intelectual.
Autopercepción e insatisfacción de la imagen corporal con relación al IMC y porcentaje de grasa entre hombres y mujeres estudiantes universitarios chilenos
Authors: Inzunza Rosales Edwin , Díaz Tapia Cinthia , Valenzuela Manríquez Esteban , Gutiérrez Vergara Yovely , Baier Riquelme Bárbara , Molina-Márquez Iván , Hernàndez-Mosqueira Claudio 
Published: December 2022

Introducción: Uno de los factores que condiciona el peso corporal es la percepción de la imagen corporal. En estudiantes universitarios la ingesta de comida rápida puede generar dificultades en la autopercepción de la imagen corporal como lo son la subestimación o sobreestimación del estado nutricional, llegando a producir trastornos como anorexia, bulimia e intentos de suicidio.
Objetivo: Comparar la autopercepción de la imagen corporal, insatisfacción corporal, índice de masa corporal (IMC) y porcentaje de grasa corporal entre mujeres y hombres de la Universidad Adventista de Chile.
Material y métodos: Estudio de tipo descriptivo comparativo de diseño transversal, aplicado a 150 estudiantes regulares de la Universidad Adventista de Chile, Chillán (UnACh). Se realizaron evaluaciones antropométricas (IMC y pliegues cutáneos), aplicación de Body Shape Questionnaire (BSQ) y Test de Modelo anatómico de Montero (MAM).
Resultados: Entre los principales hallazgos se presentaron diferencias entre hombres y mujeres tanto en el BSQ como en el porcentaje de grasa, no así en el MAM y en el IMC donde no se encontraron diferencias significativas.
Conclusiones: Las mujeres evaluadas poseen mayor insatisfacción corporal y porcentaje de grasa que los hombres universitarios; sin embargo, tanto hombres como mujeres poseen autopercepción corporal que se ajusta a su IMC, no habiendo diferencias significativas entre ambos sexos.
Comparative assessment of results of D2 and D3 lymph node dissections in term of colon cancer surgery
Authors: Kit O. I. , Dzhenkova E. A. , Mirzoyan E. A. , Gevorkyan Yu. A. , Kolesnikov E. N. , Snezhko A. V. 
Published: December 2022

Purpose of the study. Was to evaluate overall survival of CC patients after D2 and D3 lymph node dissections and assess the frequency of postoperative complications and dynamics of postoperative recovery.Materials and methods. The study included 50 CC patients aged 39–84 years.Results. The comparative assessment of the overall survival, frequency of postoperative complications and dynamics of postoperative recovery was performed in patients divided into 2 groups depending on the lymph node dissection extent. Group 1 included 23 patients (46 %) with D2 lymph node dissection, group 2–27 patients (54 %) with D3 lymph node dissection. 8 (16 %) patients developed complications in the early postoperative period. Patients in group 1 had grade I (5 patients) and grade IIIb (1 patient) surgical complications, according to the Clavien-Dindo classification. 2 patients in group 2 developed grade III b complications. No significant differences were found between groups in peristalsis, gases and bowel movement, starting eating and drinking. A significant increase in the number of postoperative bed-days was observed in patients who underwent open surgery, compared with the group with laparoscopic access. No statistically significant difference was found in the overall survival in patients of the two groups (p = 0.918).Conclusion. The rates of postoperative complications that required repeated surgery were comparable between the groups with D2 and D3 lymph node dissections. D3 lymph node dissection did not affect the dynamics of postoperative recovery and the overall survival of patients.
Male infertility along with the era of coronavirus infection SARS-CoV-2
Authors: Kulchenko N. G. , Druzhinina N. K. , Myandina G. I. 
Published: December 2022

Russian and foreign epidemiological data suggest that males may have an increased risk of morbidity and mortality associated with COVID‑19. It is known that due to the high expression of ACE2 in spermatogonia, Leydig and Sertoli cells, the testicle, as an organ producing male germ cells, is a potential target for the COVID‑19 virus, which directly affects the reproductive health of men. To date, several factors of the influence of the SARS-CoV‑2 virus on the male reproductive system are known. To begin with, when infected, the virus has a direct damaging effect on the testicle itself with the provocation of orchitis. In addition to the previous statement, high body temperature during inflammation contributes to an increase in testicular temperature, which can lead to a deterioration in the quality of sperm. Furthermore, a pronounced inflammatory reaction promotes the circulation of a large number of cytokines and damage to the hemato-testicular barrier. Also, the increased activity of immunocytes leads to an imbalance of the antioxidant system of men, an increase in the level of reactive oxygen species and the formation of oxidative stress. In a Nutshell, Leydig cell dystrophy provokes the development of secondary hypogonadism. Thus, COVID‑19, like a “multifaceted Janus”, has a polysymptomatic manifestation, but at the same time has a multifactorial effect on the reproductive function of a man. All these factors of the impact of the SARS-CoV‑2 virus on the testicle must be considered when rehabilitating the patient. It should be kept in mind that the deterioration of sperm quality is observed both during the acute period of coronavirus infection and during recovery period. Therefore, laboratory evaluation of the ejaculate in dynamics and its correction is necessary for males, especially those who plan to realize their reproductive potential.Conclusion. COVID‑19 generally has a negative impact on spermatogenesis and male fertility. To date, the timing and degree of restoration of a man’s reproductive function after a coronavirus infection remains completely unknown. Therefore, both in the early and late rehabilitation period, men of reproductive age need the supervision of an andrologist.
Staff policy issues in scientific research
Authors: Armashevskaya O. V. , Menshikovа L. I. 
Published: December 2022

Purpose of the study. Analysis of implemented personnel practices presented in dissertations in the specialty 14.02.03. Public health and healthcare for 2016–2020.Materials and methods. We used data from the website of the Higher Attestation Commission under the Ministry of Science and Higher Education of the Russian Federation. Of the 220 dissertations, the authors of which were awarded the degree of candidate or doctor of medical sciences in the specialty 14.02.03 Public health and health care, 21 scientific papers devoted to personnel issues were singled out. In this study, a descriptive-analytical method was applied.Results. Dissertations covering a fifteen-year period since the beginning of the modernization of healthcare revealed a number of problems: low wages; insufficient staffing, disproportion between doctors and paramedical workers; difficult working conditions, the outflow of personnel from the industry in general, as well as from public health institutions to private medical organizations. Approbation of developments and implementation on the basis of research, evaluation of their effectiveness allowed the authors to offer recommendations for implementation in healthcare practice, starting with the Ministry of Health of the Russian Federation, government bodies of the subject of the Federation, a medical organization, educational institutions and ending directly with the object of study – management personnel, doctors, secondary medical worker. The study and analysis of personnel practices presented in scientific research makes it possible to determine the most relevant areas for the formation of personnel policy.Conclusion. The results of the study showed a small number of dissertations (9.5 %) devoted to personnel issues and defended in the specialty 14.02.03. Public health and healthcare, despite the decisive role of human resources in the innovative development of the country’s healthcare. The studies covered all groups of medical workers, managers, students of medical universities, colleges and included the study of the state of health, motivation, job satisfaction, leadership training, interaction between medical workers of different levels and patients. Effective practices are proposed that can be replicated at the regional level, new ones can be created on their basis, and they also make it possible to determine the criteria for assessing staff policy in a medical organization, subject and country.
A comparative study of different contrast administration routes efficiency performed on in vivo colorectal cancer models
Authors: Goncharova A. S. , Khodakova D. V. , Galina A. V. , Zaikina A. V. , Kurbanova L. Z. , Mindar M. V. , Gurova S. V. 
Published: December 2022

Purpose of the study. The investigation is aimed to provide a systematic comparison of different contrasting methods for in vivo micro-CT diagnostic of orthotopic colorectal cancer models extracted by ortotopic implantation into the caecum of immunocompromised mice BALB/c Nude lines.Materials and methods. BALB/c Nude (N = 25) female mice were implanted by transplanted human colorectal cancer strain into the cecum. 20 days after the implantation mice were administered with iodine-based contrast agent Optiray by means of different administration method (intravenously, per os, intraperitoneally, per rectum) and micro-CT scans have been registered via Quantum GX2 tomograph. Measurement of tumor nodes was performed both by means of estimation from micro-CT images via RadiAnt DICOM Viewer software and by means of explicit measurements using calipers upon laparotomy and posthumously. At the last stage of the study, the animals were euthanized by cervical dislocation. The tumors were excised, measured with a caliper and placed in 10 % formalin for the standard histological analysis according to the standard methods.Results. The average volumes of tumor xenografts in animals with intravenous, oral, and intraperitoneal contrast administration measured at micro-CT were 53.7 ± 5.2 mm3, 52.7 ± 6.4 mm3 and 63.6 ± 5.6 mm3 respectively; measured at laparotomy – 43.0 ± 5.5 mm3, 44.5 ± 5.4 mm3 and 58.5 ± 5.5 mm3 respectively; measured post-mortem – 55.2 ± 6.6 mm3, 53.2 ± 8.8 mm3 and 65.9 ± 3.8 mm3 respectively. The average volumes of tumor xenografts isolated post-mortem in these groups were comparable with the values shown at micro-CT, but larger than the volumes measured at laparotomy.Conclusion. The results obtained demonstrated that intravenous, peroral and intraperitoneal administration techniques provide the best visualization of laboratory rodents pathological tissue upon in vivo micro-CT diagnostics and thus are preferred.
Role of hypothalamic-pituitary-adrenal axis and catecholamine factors in independent and primary multiple types of tumor growth
Authors: Frantsiyants E. M. , Bandovkina V. A. , Kaplieva I. V. , Surikova E. I. , Pogorelova Yu. A. , Cheryarina N. D. , Trepitaki L. K. , Neskubina I. V. , Vereskunova A. A. , Kotieva I. M. , Shumarin K. A. , Shikhlyarova A. I. , Goroshinskaya I. V. 
Published: December 2022

Purpose of the study. To study the levels of adrenal axis factors in the hypothalamus, adrenal glands, blood serum of mice and catecholamines in the adrenal glands during the independent growth of B16 melanoma and Lewis lung carcinoma (LLC) and their combined growth in female mice, and in males – with independent growth of B16 and combined growth of B16 and LLC.Materials and methods. Male and female BALB/c Nude mice were divided into groups, n = 7 each: group 1 involved intact animals, group 2 involved mice with B16/F10 melanoma, group 3 – mice with LLC, group 4 – synchronous growth of melanoma and LLC. Levels of corticotropin releasing, noradrenaline and dopamine were determined in homogenates of the hypothalamus and adrenal glands and in the blood serum of all animals by ELISA, and levels of 17‑hydroxyprogesterone (17-OHP), dehydroepiandrosterone sulfate (DHEA-S) and cortisol were determined by RIA. Statistical processing of results was performed using the Statistica 10.0 program.Results. All tumor-bearing females showed elevated corticotropin releasing in the hypothalamus together with an increase of all stress-characterizing parameters: cortisol, the cortisol/DHEA-S ratio, and noradrenaline. However, an increase in serum levels of cortisol was blocked by high levels of DHEA-S, and as a result, the cortisol/DHEA-S ratio was either within the normal range (B16 melanoma and B16+LLC combination) or reduced (LLC). Levels of corticotropin releasing in the hypothalamus of tumor-bearing males decreased, together with opposite changes in stress-characterizing parameters in the adrenal glands: cortisol increased, the cortisol/DHEA-S ratio did not differ significantly from the control values, and noradrenaline decreased. An increase in serum levels of cortisol was not blocked by high levels of DHEA-S, and as a result, the cortisol/DHEA-S ratio was sharply elevated in B16 melanoma and B16+LLC combination.Conclusion. At independent and primary multiple types of tumor growth, the sex-specific features of the functioning of the adrenal axis at the central and peripheral levels are observed, which determines a more pronounced stressful state of the body with B16+LLC combination growth, realized by various mechanisms.
Evaluation of Toll-like receptors expression in terms of colon cancer
Authors: Dzhenkova E. A. , Mirzoyan E. A. , Sagakyants A. B. , Bondarenko E. S. , Zlatnik E. Yu. , Shaposhnikov A. V. , Kolesnikov E. N. , Kaymakchi O. Yu. , Dashkov A. V. , Kaminskiy G. V. , Milakin A. G. , Malinin S. A. , Savchenko D. A. , Chalkhakhyan L. Kh. 
Published: December 2022

Purpose of the study. To evaluate the number of cells with the CD45+/- phenotype expressing Toll-like receptors (TLRs) in tissues of the tumor, peritumoral area and resection line tissues in colon cancer (CC) with various tumor locations.Materials and methods. The study included 50 patients with CC. All patients underwent surgery as the primary treatment, and tissue material was collected from the patients. Expression of TLRs (2, 3, 4, 8, 9) on CD45+, CD45- cell populations was determined by flow cytometry in cell suspensions obtained from tissues of the tumor, peritumoral area (1–3 cm from the tumor) and resection line tissues (~10 cm from the tumor) with further calculation of the percentage of cells with the corresponding phenotype from the total number of cells.Results. An analysis of left-sided colon tumors showed lower percentage of CD45- cells expressing TLR4, 8, compared to rightsided tumors, by 38 % and 25 %. A comparative analysis of the number of CD45+ cells expressing TLR 2, 4 showed their decrease by 81 % and 87 %, respectively, compared with right-sided tumors. An assessment of the data in the perifocal zone of left-sided colon tumors, compared with right-sided ones, demonstrated a decrease in the percentage of cells with the CD45- phenotype that express TLR4, by 61 %. Resection line tissues in left-sided tumors, compared with right-sided ones, showed a statistically significant increase in the percentage of CD45- cells that express TLR 2, 4 by 205 % and 55 %, respectively. The number of CD45+ cells expressing TLR 4 decreased by 87 %. An assessment of the number of cells expressing TLRs 3 and 9 in the tumor, peritumoral area and resection line tissues did not reveal significant differences.Conclusions. Lower number of cells with CD45+ and CD45- phenotypes express TLRs 2, 4, 8 in left-sided colon tumors and their peritumoral tissues, compared to right-sided cancer.