bluuebunny/crossref_metadata_2025_split huggingface dataset:
Species composition and biogeographical affinities of polychaetes (Annelida) from the southern Mexican Pacific shelf
Authors: Hernández-Alcántara Pablo , Velasco-López Francisco F. , Quiroz-Martínez Benjamín , Solís-Weiss Vivianne 
Published: September 2023

Abstract
Polychaetes from tropical ecosystems of the eastern Pacific have been poorly studied; thus, the aim of this study was to analyse their taxonomic composition in the southern Mexican Pacific shelf and to examine their biogeographic affinities. A total of 3741 specimens from 82 species, 52 genera, and 27 families were identified from 38 stations at 42–109 m depth. The Sedentaria group was more diverse (40 species, 48.8%) and abundant (1753 ind., 46.9%) compared to the Errantia (36 species, 43.9%; 346 ind., 9.2%) and the Basal Annelida groups (6 species, 7.3%; 1642 ind., 43.9%). The families Onuphidae (14 spp.), Spionidae (8 spp.), and Paraonidae (8 spp.) were the most diverse. The Amphinomidae and Spionidae accounted for 72.6% of the fauna; the remarkably high abundance of both families together is unusual in the tropical eastern Pacific. The polychaete species had high biogeographic affinities with the Mexican tropical Pacific ecoregion (45.1%), which has tropical conditions, and the Cortezian (29.3%), which has warm-temperate characteristics. Twelve amphiamerican species and ten with worldwide distribution were found. The tropical eastern Pacific is one of the world regions with the lowest number of polychaete records, thus underlining the importance of the taxonomic and biogeographic information provided here. The sampling effort should increase, since the non-parametric estimators indicated that 116–138 species were expected, instead of the 82 species actually found.
Factors associated with depression among healthcare workers during the COVID-19 pandemic: a systematic review and meta-analysis
Authors: Tian Haoyu , Qiao Tianci , Teng Jing , Kang Chen , Ke Jia , Shan Lili , Li Mengting , Shen Chun , Han Yan 
Published: September 2023

AbstractThe COVID-19 pandemic has had a profound impact on the mental health of healthcare workers (HCWs). We aimed to identify the factors associated with depression among HCWs during the pandemic. We conducted literature search using eight electronic databases up to July 27 2022. Observational studies with more than 200 participants investigating correlates of depression in HCWs after COVID-19 outbreak were included. We used fixed- and random-effects models to pool odds ratios (ORs) across studies, and Cochran's chi-squared test andI2statistics to assess study heterogeneity. Publication bias was evaluated by funnel plots. Thirty-five studies involving 44,362 HCWs met the inclusion criteria. Female (OR=1.50, 95% CI [1.23,1.84]), single (OR=1.36, 95% CI [1.21,1.54]), nurse (OR=1.69, 95% CI [1.28,2.25]), history of mental diseases (OR=2.53, 95% CI [1.78,3.58]), frontline (OR=1.79, 95% CI [1.38,2.32]), health anxiety due to COVID-19 (OR=1.88, 95% CI [1.29,2.76]), working in isolation wards (OR=1.98, 95% CI [1.38,2.84]), and insufficient personal protective equipment (OR=1.49, 95% CI [1.33,1.67]) were associated with increased risk of depression. Instead, HCWs with a positive professional prospect (OR=0.34, 95% CI [0.24,0.49]) were less likely to be depressed. This meta-analysis provides up-to-date evidence on the factors linked to depression among HCWs during the COVID-19 pandemic. Given the persistent threats posed by COVID-19, early screening is crucial for the intervention and prevention of depression in HCWs.
Scientism and the value of scientific evidence for religious belief
Authors: Warman Jack , De Brasi Leandro 
Published: September 2023

AbstractThis article presents a novel argument against an application of evidential scientism to religious belief. In particular, our target is those arguments at whose core lies the claim that it ought to be the case that, if one holds religious beliefs, then those beliefs are based on the best scientific evidence. Moreover, rather than focussing on the philosophical puzzles that usually fall within the purview of philosophers of religion, we are interested in the mundane beliefs of ordinary believers about their everyday interactions with God. Our argument combines recent work on epistemic partiality in close personal relationships with insights from analytic theology on the personal nature of believer's relationships with God. We argue that it's inappropriate for believers who take themselves to have a personal relationship with God to base their religious beliefs about God's nature on scientific evidence. In particular, it's precisely because these believers are in a personal relationship with God that it's sometimes inappropriate for them to form their beliefs about God's nature on the basis of scientific evidence.
V2 violations in different variants of Icelandic: A common denominator?
Authors: Angantýsson Ásgrímur , Nowenstein Iris Edda , Thráinsson Höskuldur 
Published: September 2023

AbstractIn this article, we report on a number of violations of (or exceptions to) the so-called V2 constraint in different variants of Icelandic. The main purpose is to investigate what these violations can tell us about the nature of the V2 constraint, its vulnerability, the limits of syntax, and about children’s ability to sort out what is relevant and what is not in the input they hear during the acquisition period. Three main explanatory possibilites are taken under consideration: the use and acceptance of sentences with V2 violations in Icelandic (i) is due to English influence, (ii) indicates an expansion of patterns existing in the language for language-internal reasons, (iii) is due to a task effect. In brief, our results support (i) for heritage Icelandic but not for non-heritage Icelandic, while different subsets of our data are best accounted for in terms of either (ii) or (iii).
Epidemiology and molecular typing of multidrug-resistant bacteria in day care centres in Flanders, Belgium
Authors: van Kleef – van Koeveringe Stefanie , Matheeussen Veerle , Jansens Hilde , Perales Selva Natascha , De Coninck Dieter , De Bruyne Katrien , Mensaert Klaas , Kluytmans - van den Bergh Marjolein , Kluytmans Jan , Goossens Herman , Dhaeze Wouter ,   on behalf of the i-4-1-Health Study Group
Published: September 2023

Abstract
The global prevalence and spread of multidrug-resistant organisms (MDROs) represent an emerging public health threat. Day care centre (DCC) attendance is a risk factor for MDRO carriage in children and their environment. This study aimed to map the epidemiology of carriage and potential transmission of these organisms within 18 Flemish DDCs (Belgium). An MDRO prevalence survey was organised between November 2018 and February 2019 among children attending the centres. Selective chromogenic culture media were used for the detection of extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-E), carbapenemase-producing Enterobacterales (CPE), and vancomycin-resistant Enterococci (VRE) in faecal swabs obtained from diapers or jars (n = 448). All isolated MDROs were subjected to resistance gene sequencing. A total of 71 of 448 samples (15.8%) yielded isolates of ESBL-E with a predominance of Escherichia coli (92.2% of ESBL-E) and ESBL resistance gene blaCTX-M-15 (50.7% of ESBL coding genes in E. coli). ESBL-E prevalence varied between DCCs, ranging from 0 to 50%. Transmission, based on the clonal relatedness of ESBL-E strains, was observed. CPE was identified in only one child carrying an E. coli with an OXA-244 gene. VRE was absent from all samples. The observed prevalence of ESBL-E in Flemish DCCs is high compared with previous studies, and our findings re-emphasise the need for rigorous hygiene measures within such centres to control the further spread of MDROs in the community.
Promoting plant-based eating in meat-centric meal contexts: a field study
Authors: Guedes David , Brazão Vasco , Roque Lisa , Campos Lúcia , Godinho Cristina , Truninger Monica , Vinnari Markus , Graça João 
Published: September 2023

AbstractObjective:Shifting from meat-centric to plant-rich diets may help to enable healthier and more sustainable food systems. Here we present the results of a 1-week intervention to promote plant-based eating in a meat-centric food context (i.e. canteen).Design:The intervention included environmental restructuring strategies (e.g. promotional materials and menu redevelopment) and improvements to the offer of plant-based meals. The evaluation (sales data; pre-registered) spanned 3 weeks prior to the intervention (baseline), 1 week during the intervention (immediate/short-term impact) and 3 weeks after the intervention (follow-up). Opinion surveys were also used to collect data with customers during the intervention.Setting:Canteen unit of a university campus in Portugal (Lisbon metropolitan area).Participants:In addition to sales data (baseline: 7965 meals; immediate/short-term: 2635 meals; follow-up: 7135 meals), we used opinion surveys to assess customers’ meal appraisals during the intervention (n = 370).Results:The odds of a sold meal being vegetarian were 24 % higher in the intervention week compared with the pre-intervention period [OR = 1·24, 95 % CI (1·10, 1·40)] and 9 % higher in the post-intervention period compared with the pre-intervention period [OR = 1·09, (95 % CI (1·00, 1·19)]. Survey data showed that vegetarian meals compared favourably to meat and fish alternatives in liking, sustainability and satiety.Conclusions:A short-term, theory-driven, operationally feasible intervention was effective in promoting increased plant-based meal choices in a collective meal context. Nevertheless, these changes were not entirely sustained over time. Future studies could test whether prolonged or more transformative interventions are necessary to unlock entrenched food practices more effectively in meat-centric collective meal contexts.
ODYSSEAN MEDIATIONS IN EUDOCIA'SMARTYRDOM OF ST CYPRIAN
Authors: Praticò Domenico 
Published: September 2023

ὑμετέρης γενεῆς τε καὶ αἵματος εὔχομαι εἶναι(Eudocia'sLaudes Antiochiae; cf.Il. 6.211, 20.241).1The article argues that in Eudocia's fifth-centuryMartyrdom of St Cyprian– the only surviving Greek verse paraphrase of a hagiography – certain Odyssean lexical items and intertexts may be thematically grouped. A new category, the ‘diatext’, is introduced to describe this function of theOdysseyas an intermediate thematic model used to transpose the Cyprianic hagiographies (the ‘hypotext’) into Eudocia's verse paraphrase (the ‘hypertext’). A particularly important and complex example is the way in which Eudocia's metapoetic/narratorial and biographical alter ego, the ex-pagan Christian convert Cyprian, is modelled after Odysseus (especially in book 2).
Police Shooting Statistics and Public Support for Police Reforms
Authors: Schiff Kaylyn Jackson , Clark Tom S. , Glynn Adam N. , Owens Michael Leo , Gunderson Anna , Dobbie Eric 
Published: September 2023

AbstractDoes providing information about police shootings influence policing reform preferences? We conducted an online survey experiment in 2021 among approximately 2,600 residents of 10 large US cities. It incorporated original data we collected on police shootings of civilians. After respondents estimated the number of police shootings in their cities in 2020, we randomized subjects into three treatment groups and a control group. Treatments included some form of factual information about the police shootings in respondents’ cities (e.g., the actual total number). Afterward, respondents were asked their opinions about five policing reform proposals. Police shooting statistics did not move policing reform preferences. Support for policing reforms is primarily associated with partisanship and ideology, coupled with race. Our findings illuminate key sources of policing reform preferences among the public and reveal potential limits of information-driven, numeric-based initiatives to influence policing in the US.
Lithospheric Structure of the Circum‐Pannonian Region Imaged by S‐To‐P Receiver Functions
Authors: Kalmár Dániel , Petrescu Laura , Stipčević Josip , Balázs Attila , János Kovács István ,   the AlpArray and PACASE Working Groups
Published: September 2023

AbstractThe lithosphere‐asthenosphere boundary and mid‐lithospheric discontinuities are primary attributes of the upper mantle. The Pannonian region is an extensional sedimentary basin enclosed by collisional orogens. Here, we estimate the negative phase depth of S‐to‐P receiver functions to image the lithospheric thickness and other discontinuities with high resolution, based on the recent dense seismological broadband networks. The lithosphere‐asthenosphere boundary is relatively shallow (<90 km) in the Pannonian Basin system, and deeper (∼90–140 km) in the surrounding orogens, where average surface heat flow values are higher (120 mW/m2) and lower (50–70 mW/m2), respectively. The 1D and 2D common conversion point migration with 3D velocity model provide comparable but different resolution images beneath the wider region of the Pannonian Basin. We obtained deeper values in the Western (∼120 km) and Southern‐Carpathians orogens (∼135 km). Furthermore, we provide new information on the lithospheric thickness and its seismic properties in the eastern part of the study region (e.g., Apuseni Mountains (∼95 km), Eastern‐Carpathians (∼120 km), Moesian Platform (∼90 km) and Transylvanian Basin (∼85 km). The shallower negative phase depth can be interpreted as the lithosphere‐asthenosphere boundary beneath the Pannonian Basin system in agreement with its high heat flow values. In contrast, the deeper negative phase depth estimates in the colder surroundings can be interpreted as intra‐ or mid‐lithospheric discontinuities, when compared with local seismic tomography models. In this region, the correlation with heat flow implies that the observed negative phase depth is of thermo‐chemical or rheological nature.
Introducing the Idea of Classifying Sets of Permanent GNSS Stations as Benchmarks for Hydrogeodesy
Authors: Klos A. , Kusche J. , Leszczuk G. , Gerdener H. , Schulze K. , Lenczuk A. , Bogusz J. 
Published: September 2023

AbstractWe propose a novel approach to classify sets of Global Navigation Satellite System (GNSS) permanent stations as benchmarks for hydrogeodesy. Benchmarks are trusted sets of GNSS stations whose displacements are classified as significantly and positively correlated with hydrospheric changes and identified in a three temporal‐scales: short‐term, seasonal and long‐term. We use 63 vertical displacement time series processed at the Nevada Geodetic Laboratory for the period 1998–2021 from stations located within Amazon basin and show that estimates of trends and annual signals, including the annual phase maximum, are very coherent with water surface levels provided by altimetry missions. We compute vertical displacements from Gravity Recovery and Climate Experiment (GRACE) and GRACE Follow‐On gravity missions and predict those also from Global Land Water Storage (GLWS) v2.0 data set which values are produced by assimilation of GRACE into WaterGAP Global Hydrological Model (WGHM). We divide vertical displacements from the three data sets into the pre‐defined temporal‐scales of short‐term, seasonal and long‐term, using non‐parametric wavelet analysis. For each temporal‐scale, correlation coefficients are computed between GNSS‐measured and GRACE‐derived/GLWS‐predicted displacements. We present the benefits of applying high‐resolution GRACE‐assimilating hydrology model to benchmark GNSS stations, which are particularly evident when using spherical harmonic coefficients higher than 120. Their increase causes the number of stations included in the benchmarks to rise by up to 15% for short‐term. Benchmarking allows hydrogeodesy to take advantage of a broader set of GNSS stations that were previously omitted, such as earthquake‐affected sites and those where a possible poroelastic response is observed.
The Role of In‐Cloud Wet Removal in Simulating Aerosol Vertical Profiles and Cloud Radiative Forcing
Authors: Shan Yunpeng , Liu Xiaohong , Lin Lin , Ke Ziming , Lu Zheng , Tilmes Simone , Gao Lan , Yu Pengfei 
Published: September 2023

AbstractAmong the physical processes controlling aerosol vertical profiles, in‐cloud wet removal is of utmost importance while its representation in global climate models (GCMs) is crude. In this study, we implement into the Community Atmosphere Model version 6 (CAM6) a physically‐based aerosol wet removal parameterization scheme that explicitly treats aerosol activation, removal and resuspension. Evaluation against in‐situ observations shows that the default scheme substantially overestimates the upper tropospheric black carbon (BC) and sea salt mass. Our physically‐based scheme reduces BC and sea salt mass by a factor of 10 and 1,000, respectively, in better agreement with observations. Also, the new scheme slightly increases number of aerosol particles between 12 nm and 4.8 μm in diameter, thereby mitigating the aerosol number underestimation in the default scheme. Our new scheme reduces the overestimation of coarse‐mode aerosol (0.5–4.8 μm) number. Overall, the aerosol property changes (mass decrease and number increase) reduce the cloud condensation nuclei (CCN) concentration at low supersaturation (i.e., 0.02% and 0.1%), and increase CCN at high supersaturations (i.e., 0.5% and 1%). Consequently, the global annual mean cloud liquid water path increases by 1.89 g m−2 and the ice water path increases by 0.51 g m−2. The global annual mean shortwave, longwave, and net cloud radiative forcing change by −1.06, 0.57, and −0.48 W m−2, respectively. Further improvement is needed to reflect the real physics that the removal efficiencies for aerosol mass and number are disproportionate and to advect cloud‐borne (activated) aerosols for a complete aerosol lifecycle.
Electronic exoneuron based on liquid metal for the quantitative sensing of the augmented somatosensory system
Authors: Shang Jin , Tang Lixue , Guo Kaiqi , Yang Shuaijian , Cheng Jinhao , Dou Jiabin , Yang Rong , Zhang Mingming , Jiang Xingyu 
Published: September 2023

AbstractThe increasing demands in augmented somatosensory have promoted quantitative sensing to be an emerging need for athletic training/performance evaluation and physical rehabilitation. Neurons for the somatosensory system in the human body can capture the information of movements in time but only qualitatively. This work presents an electronic Exo-neuron (EEN) that can spread throughout the limbs for realizing augmented somatosensory by recording both muscular activity and joint motion quantitatively without site constraints or drift instability, even in strenuous activities. Simply based on low-cost liquid metal and clinically used adhesive elastomer, the EEN could be easily fabricated in large areas for limbs. It is thin (~120 μm), soft, stretchable (>500%), and conformal and further shows wide applications in sports, rehabilitation, health care, and entertainment.
Histological diagnosis of polyploidy discriminates an aggressive subset of hepatocellular carcinomas with poor prognosis
Authors: Matsuura Takanori , Ueda Yoshihide , Harada Yoshiyuki , Hayashi Kazuki , Horisaka Kisara , Yano Yoshihiko , So Shinichi , Kido Masahiro , Fukumoto Takumi , Kodama Yuzo , Hara Eiji , Matsumoto Tomonori 
Published: September 2023

Abstract
Background
Although genome duplication, or polyploidization, is believed to drive cancer evolution and affect tumor features, its significance in hepatocellular carcinoma (HCC) is unclear. We aimed to determine the characteristics of polyploid HCCs by evaluating chromosome duplication and to discover surrogate markers to discriminate polyploid HCCs.

Methods
The ploidy in human HCC was assessed by fluorescence in situ hybridization for multiple chromosomes. Clinicopathological and expression features were compared between polyploid and near-diploid HCCs. Markers indicating polyploid HCC were explored by transcriptome analysis of cultured HCC cells.

Results
Polyploidy was detected in 36% (20/56) of HCCs and discriminated an aggressive subset of HCC that typically showed high serum alpha-fetoprotein, poor differentiation, and poor prognosis compared to near-diploid HCCs. Molecular subtyping revealed that polyploid HCCs highly expressed alpha-fetoprotein but did not necessarily show progenitor features. Histological examination revealed abundant polyploid giant cancer cells (PGCCs) with a distinct appearance and frequent macrotrabecular-massive architecture in polyploid HCCs. Notably, the abundance of PGCCs and overexpression of ubiquitin-conjugating enzymes 2C indicated polyploidy in HCC and efficiently predicted poor prognosis in combination.

Conclusions
Histological diagnosis of polyploidy using surrogate markers discriminates an aggressive subset of HCC, apart from known HCC subgroups, and predict poor prognosis in HCC.
A microprotein N1DARP encoded by LINC00261 promotes Notch1 intracellular domain (N1ICD) degradation via disrupting USP10-N1ICD interaction to inhibit chemoresistance in Notch1-hyperactivated pancreatic cancer
Authors: Zhai Shuyu , Lin Jiewei , Ji Yuchen , Zhang Ronghao , Zhang Zehui , Cao Yizhi , Liu Yang , Tang Xiaomei , Liu Jia , Liu Pengyi , Lin Jiayu , Li Fanlu , Li Hongzhe , Shi Yusheng , Fu Da , Deng Xiaxing , Shen Baiyong 
Published: September 2023

AbstractThe extensively activated Notch signaling pathway in pancreatic cancer cells is important in carcinogenesis, chemoresistance, and recurrence. Targeting this pathway is a promising therapeutic strategy for pancreatic cancer; however, few successful approaches have been reported, and currently used molecular inhibitors of this pathway exhibit limited clinical benefits. In this study, we identified a previously uncharacterized microprotein, Notch1 degradation-associated regulatory polypeptide (N1DARP), encoded by LINC00261. N1DARP knockout accelerated tumor progression and enhanced stem cell properties in pancreatic cancer organoids and LSL-Kras, LSL-Trp53, and Pdx1-Cre (KPC) mice. Mechanistically, N1DARP suppressed canonical and non-canonical Notch1 pathways by competitively disrupting the interaction between N1ICD and ubiquitin-specific peptidase 10 (USP10), thereby promoting K11- and K48-linked polyubiquitination of N1ICD. To evaluate the therapeutic potential of N1DARP, we designed a cell-penetrating stapled peptide, SAH-mAH2-5, with a helical structure similar to that of N1DARP that confers remarkable physicochemical stability. SAH-mAH2-5 interacted with and promoted the proteasome-mediated degradation of N1ICD. SAH-mAH2-5 injection provided substantial therapeutic benefits with limited off-target and systemic adverse effects in Notch1-activated pancreatic cancer models. Taken together, these findings confirm that N1DARP acts as a tumor suppressor and chemosensitizer by regulating USP10-Notch1 oncogenic signaling, and suggest a promising therapeutic strategy targeting the N1DARP–N1ICD interaction in Notch1-activated pancreatic cancer.