bluuebunny/crossref_metadata_2025_split huggingface dataset:
Data-Driven Decision Support for Post-Hospitalization Diabetes Case Management Referral: Protocol for Predictive Analysis
Authors: Lee Seung-Yup , Hayes Leslie , Ozaydin Bunyamin , Howard Steven , Garretson Alison , Bradley Heather , Land Andrew , DeLaney Erin , Pritchett Amy , Furr Amanda , Allgood Ashleigh , Wyatt Matthew , Hall Allyson , Banaszak-Holl Jane 
Published: July 2023

Abstract
Background
While diabetes cases become more complex with increasing age and comorbidity, social determinants of health (SDoH), including food security, medication availability, and transportation, act as a significant source of disparities in diabetes risk and outcomes. However, with the existing supply-demand mismatch in diabetes case management, current case management referrals are primarily based on the most apparent clinical information. Data-driven decision support that learns from large-scale electronic health records (EHRs) encompassing the SDoH is a promising approach to helping prioritize demand and alleviate disparities through the identification of patients at highest risk.
Methods
This protocol is for a predictive analysis study to develop a proactive risk assessment decision support (PRADS) model incorporating the SDoH data to stratify urgency of needed case management among diabetic patients by identifying patients that are likely to utilize extensive resources including hospitalizations and emergency department (ED) visits. We will collect EHR data spanning from January 2018 to February 2023 from a Level 1 Trauma Center in Southeast (where diabetes and disparities have been prevalent), including demographics, SDoH, comorbidities, laboratory test results, access to care, medications, and the outcome variables (i.e., readmissions and ED visits). The dataset includes 65,821 unique inpatients that account for 132,273 inpatient encounters. 70% of the data observations will be utilized to train a Survival Decision Tree model, and the rest to generate prediction outcomes (probability of readmission or ED visit). The model will be validated in a quantitative manner by evaluating performance evaluation metrics and in a qualitative manner by conducting a three-phase modified Delphi method that involves the case management, clinician, and quality and patient safety teams.
Discussion
Despite the multifaceted disparities among diabetic patients, e.g., comorbidities and social support, the current case management referral process does not involve a comprehensive assessment of patient information. Data-driven decision support that learns from a wide range of SDoH and clinical information can help better identify high-risk patients for effective utilization of the current workforce. The PRADS model may demonstrate the value of SDoH in estimating diabetes risk factors, potential for system implementation, and improvement in utilizing the case management workforce.
Analysing the Segreggation Ratio of Grain Amaranth Cross (Suvarna X Ga2)
Authors: Mishra Madhuchhada , Chatterjee Suchismita , Sagar Preeti , Tiwari Jitendra Kumar 
Published: July 2023

Abstract
Grain Amaranthus is a potential pseudocereal cereal which has the capability to ensure balanced nutrient availability and can cope up with the degrading environment. The present study was conducted to identify the pattern of inheritance of 9 important morphological traits in the F2 segregating population of 2 well known, cultivated varieties of grain amaranth i.e., Suvarna X GA2. The F1 plants were found to be green colour (green leaf and stem) having red leaf margin, red colour, erect, flat inflorescence but with spreading growth habit with late flowering, indicating these characters to be dominant over the other contracting character(s). In F2 we found out that Leaf colour and Flowering time followed Supplementary gene action; Panicle Colour and Inflorescence shape following Polymorphic gene action; Plant growth habit and inflorescence spiney were found to follow Inhibitory genre action and Presence of red leaf margin, Stem colour and inflorescence compactness were found to follow normal Mendelian segregation.
Tax Revenues and Income Inequality in Sub-Saharan Africa: Evidence from a Dynamic Panel Threshold Analysis.
Authors: AZENG Therese Felicitee , HELGATH Bybert MOUDJARE 
Published: July 2023

Abstract
The main goal of this paper is to revisit the relationship between tax revenues and income inequality in 28 Sub-Saharan countries from 2000 to 2015. Applying a dynamic panel threshold model, the results find that that there is a nonlinearity link between both variables and an optimal tax revenue rate affecting income inequalities. More specifically, the optimal tax revenue rate is around 1.051%. Below this threshold, an increase of 1 percent in tax revenue rises income inequality by 0.017% and beyond this threshold, an increase of 1 percent in tax revenue reduces income inequality by 0.026%. by remaining below the optimal threshold, the authorities deprive themselves of a broadening of the tax base, lever in the fight against inequalities and poverty.
Code JEL : C36, E62, 023.
The constant domain of CRTAM is essential for high-affinity interaction with Nectin-like 2
Authors: Barragan-Galvez Juan Carlos , Lopez-Ortega Orestes , Hernandez-Flores Araceli , Rodriguez-Alvarez Adriana A. , Maravillas-Montero Jose Luis , Ortiz-Navarrete Vianney 
Published: July 2023

Abstract
CRTAM (Class-I MHC-restricted T cell-associated molecule) is a member of the Nectin-like family, composed of two extracellular domains, one constant domain (IgC), and another variable domain (IgV), expressed in activated CD8 T cells, epithelial cells, NK cells and in a subpopulation CD4 T cell. CRTAM recognizes the ligand Nectin-like 2 (Necl2) through the variable domain. However, the role of the constant domain during this ligand recognition has yet to be understood. In this study, we show the purification of soluble-folded Ig-domains of CRTAM, and we demonstrated that the constant domain forms a homodimer in solution via hydrophobic interactions. By SRP analysis, we also demonstrate that the full CRTAM binds to Necl2 with a 2.16 nM affinity. Additionally, transfected cells expressing the full length of CRTAM on the surface establish a better interaction with Necl2 than with the CRTAM-IgC domain expressed on the cell surface. In conclusion, the constant domain of CRTAM is essential for high-affinity interaction with Necl-2.
Early postoperative intra-axial dissemination of a pediatric extradural and complicated hydatid cyst
Authors: Borni Mehdi , Souissi Ghassen , Taallah Marouen , Abdelmouleh Souhir , Ayadi Ali , Boudawara Mohamed Zaher 
Published: July 2023

Abstract
Hydatid disease is very common around the Mediterranean basin and endemic in some parts of the world. Cerebral involvement remains rare, represents only about 2% of all hydatid localizations and mainly affects the pediatric population. Extradural hydatid cyst is very rare or even exceptional when it is associated with or followed by intracerebral disseminations. Here, the authors report a new exceptional case of an early multiple intra-axial hydatid dissemination in a 5-year-old North African male patient from a rural area who underwent surgery three months ago after a primary osteolytic extradural and complicated hydatid cyst with good clinical and radiological outcomes.
Fatigue behavior of teeth filled with calcium silicate- and epoxy resin-based sealers in bulk or associated with a main core material
Authors: Chiaratti Luiza Colpo , Lena Isabella Marian , Pilecco Rafaela Oliveira , Machry Renan Vaz , Pereira Gabriel Kalil Rocha , DornellesMorgental Renata 
Published: July 2023

Abstract
Objective:
To evaluate the fatigue behavior of teeth filled with a calcium silicate-based sealer (Bio-C Sealer, BC) in comparison to an epoxy resin-based sealer (AH Plus, AH), in bulk or associated with gutta-percha as main core material.
Methods:
Root canals of 72 human maxillary incisors and canines were prepared using nickel-titanium reciprocating instruments and randomly assigned to 2 control groups: C- (without preparation and filling) and C+ (prepared but not filled); and 4 experimental groups: BC-B (BC in bulk); BC-GP (BC + gutta-percha); AP-B (AH in bulk); AP-GP (AH + gutta-percha). The specimens were submitted to a survival analysis after the cyclic fatigue test.
Results:
The experimental groups showed similar fatigue behavior (P> .05), being also similar to C+ (BC-B = BC-GP = AP-B = AP-GP = C+). The C- group presented the best fatigue performance (P<.05), being similar only to the AP-GP group (P>.05). Considering a premature failure rate (~10%), lower performance is observed for experimental groups filled in bulk. Conclusions:
The use of calcium silicate-based sealer is valid, both as bulk or associated with gutta-percha as a main core material, as it resulted on similar mechanical performance to an epoxy resin-based sealer. Despite that, the use of gutta-percha, as a main core material, seems to reduce the risk of premature failures. Clinical relevance: Ah Plus associated with gutta percha as main core material show similar fatigue behavior to sound teeth. Teeth filled in bulk, without gutta-percha as main core, had higher risk of premature failures.
Enhanced nutrient (N&amp;P) removal by partially saturated and hybrid vertical flow constructed wetland from single household greywater
Authors: Punyapwar Swapnil , Mutnuri Srikanth 
Published: July 2023

Abstract
Constructed wetlands (CWs) are a group of novel, natural wastewater treatment technologies which principally house microbes with help of plants and filter media. The denitrification rates in vertical flow constructed wetland (VFCW) are sensitive and in most cases complete nitrogen removal does not occur. In current study, two systems were evaluated, 1st was partial saturated up-flow VFCW and the 2nd was hybrid pilot scale setup of VFCW and floating treatment wetland (FTW) in series. Both these systems were implemented at single household scale for treatment of greywater. VFCW filter media were river sand and gravels with Canna indica as macrophyte. FTW rafts were made of thermocol sheets covering 100% of water surface in tank. System sampling was done for every 3rd day and pollutant removal performance was measured in terms of COD, total nitrogen (TN), ammoniacal nitrogen (NH4-N), nitrate (NO3-N), nitrite (NO2-N), and o-phosphate (PO4-P) concentrations of influent and effluent. Saturated VFCW system removed 89.09%, 78.7%, 67%, 68.74%, 94.6%, and 86.01% whereas hybrid wetland removed 91.5%, 92.32%, 82.2%, 71.13%, 97.25%, and 89.37% of COD, TN, NH4-N, NO3-N, NO2-N and PO4-P respectively. After stable pollutant removal trend, FTW macrophyte roots were harvested and subjected to metagenomic analysis on Illumina platform to identify microbial diversity and functional annotation related to nitrogen and phosphate removal. Microbial diversity showed Pseudomonas, Bacteroides, Clostridium, Azoarcus, Achromobacter as dominant top 5 genus. This group of genus highlights denitrifying microbial abundance greater than VFCW metagenomes microbial population. The presence of significantly higher denitrifying microbes in FTW confirms higher denitrification rate than VFCW, resulting in overall more Nitrogen removal by the system.
Medial-type persistent trigeminal artery and ipsilateral posterior communicating artery supplying bilateral posterior cerebral arteries associated with an aberrant right subclavian artery and bicarotid trunk
Authors: Uchino Akira , Kondo Ryushi 
Published: July 2023

Abstract
Purpose
To describe a case of a medial-type persistent trigeminal artery (PTA) associated with multiple arterial variations.
Methods
A 34-year-old woman with multiple sclerosis underwent cranial magnetic resonance (MR) angiography from the aortic arch to the neck region and intracranial region for the evaluation of an unruptured cerebral aneurysm that was previously detected on MR imaging. The MR machine was a 3-T scanner.
Results
There was an aberrant right subclavian artery and bicarotid trunk, medial-type left PTA and ipsilateral posterior communicating artery (PCoA) supplying bilateral posterior cerebral arteries (PCAs). The unruptured aneurysm was located at the paraclinoid segment of the left internal carotid artery and was treated successfully by coil embolization via a transfemoral approach.
Conclusion
Only 10% of PTAs are classified as the medial type. The association with hyperplastic ipsilateral PCoA, which supplies the bilateral PCAs, has not been previously reported. Aberrant right subclavian arteries are common and are frequently associated with a bicarotid trunk. Before catheterization of the cerebral arteries, the aortic arch and its branches must be evaluated by MR angiography or computed tomography angiography to prevent catheterization failure via the right transradial approach.
An excellent super-polarization-independent optical directional coupler based on dual-core photonic crystal fiber with a bandwidth of 390nm
Authors: Jiang Meng-Lin , Zou Hui , Xu Jian-Jie , Chen Yu 
Published: July 2023

Abstract
In this work, a novel structure of dual-core photonic crystal fiber (PCF) is proposed to make the super-polarization-independent optical directional coupler, which takes not only the feasibility of optical fiber manufacturing process but also the needs of practical application into account. The introduced fluorine-doped elliptical cores with a rotation angle of 45-degree successfully realize the super-polarization-independent coupling performance of less than 0.004% in the difference between coupling ratios of two polarized lights within the effective wavelength range of 1230-1620nm. In other words, it effectively offsets the damage caused by the introduction of two cores to the structural symmetry, thereby significantly reducing the difference in the coupling ratio between the two polarization states and excellently eliminating the polarization-dependence of the dual-core PCF. In addition, compared with traditional elliptical air holes, the solid elliptical structure is easier to get under control, which significantly reduces the difficulty of manufacturing. Consequently, the novel structure is expected to be applied in the optical communication network nowadays.
Are Blockchain-based assets connected to classical markets? Volatility spillover and wavelet analysis
Authors: Karoui Ali Trabelsi , Mahjoub Rabeb , Kammoun Aida 
Published: July 2023

Abstract

Following the rise of new blockchain-based assets like NFTs and DeFi tokens, alongside the high demand for cryptocurrencies, investors are altering the construction of their portfolios by not just relying on classical strategies in FOREX, stocks, and commodities markets. To highlight the overall risk transmission between the different segment of the markets, we study the connectedness using VAR and TVP-VAR models at various frequencies. We compare the t-variant components across different scales. This approach allows for the investigation of time-frequency dynamics and the identification of patterns and relationships between these assets. The study will utilize historical data and apply wavelet coherence techniques to analyze the co-movements and dependencies at various time scales. The empirical results indicate a strong correlation between DeFi, other cryptocurrencies, and Bitcoin, while NFTs exhibit independence from nearly all segments of the network. The transmission of shocks between markets depends on time and frequency, with most transmission occurring at short-term frequencies. Dynamic transmission is influenced by crises such as the COVID-19 outbreak. Our findings contribute to the literature on blockchain-based assets by examining the transmission of shocks with established markets. These results are significant for investors in managing their portfolios and making informed decisions by considering their holdings in the classical market.
JEL Classification: G11; G14 ; C5 ; C58 ; L86 ; G19
Environmental protection experience of secretaries and COD regulation: Firm-level evidence from China
Authors: Yang Zhenbing , Shao Shuai , Xu Le , Yang Lili 
Published: July 2023

Abstract
Using the firm-level data of the Chinese industrial sector from 1998 to 2010, this study investigates the impact of the previous environmental protection experience of prefecture-level Communist Party secretaries on the COD regulation within the secretaries’ respective jurisdictions. The study finds that the secretaries’ previous environmental protection experience has reduced the COD discharge intensity. The duration of the previous environmental protection experience is selected as an instrumental variable and the endogeneity is further addressed; the research conclusion remains unchanged. However, this negative impact only lasts for two years and presents an unclear long-term impact. The negative effect on COD discharge intensity caused by the previous environmental protection experience is affected by the mandatory regulation pressure from the central government and the overall polluting density of the sub-sectors. Secretaries with previous environmental protection experience do not reduce the COD discharge intensity by using the punishment mechanism of increasing sewage charges. The secretaries, instead, encourage enterprises to use clean production technology, save water resources, and reduce the produced COD level. Also, the secretaries place an emphasis on the treatment of wastewater pollutants, thus reducing the COD discharge intensity. The conclusions of this study can provide decision-making reference for the selection and training of local officials, with the goal of environmental regulation.
The Use of Puzzle Technique as an Active Learning Method in Psychiatric Semiology Teaching: A Randomized Controlled Study
Authors: Yalcinturk Aydan Akkurt , Babaoglu Elcin , Sipahi Asli Zeynep , Güres Emel Erdeniz , Dogan Selma 
Published: July 2023

Abstract
The aim of the study is to examine the effect of using puzzle technique in teaching psychiatric semiology. The sample of the study consisted of 90 students studying in the 4th year of the Nursing Department of a foundation university in Turkey and taking a psychiatric nursing course. Students were randomly assigned to intervention (n=45) and control groups (n=45). “Information Form on Psychiatric Semiology” was applied to both groups in the pre-test. A total of 6 puzzle applications were made to the students in the intervention group. Concepts related to symptoms including mental state and psychopathology are included in the puzzle content. The control group only attended the theoretical course; did not participate in the puzzle application. At the end of 6 weeks, the same information form was applied to both groups again. After the theoretical lessons and puzzle applications, the mean score of the students in the intervention group (81.95±7.69) was found to be significantly higher than the students in the control group (77.53±7.41) (p<0.05). The difference between the posttest and pretest mean scores was 24.17±10.51 in the intervention group; It was determined that it was 12.26±9.10 in the control group and the difference between pretest and posttest mean scores was statistically significant (p<0.05). Since it is seen that the use of puzzle technique is effective in teaching psychiatric semiology, it is recommended to integrate this method into traditional education methods.
Dorsal flexion maneuver of the phalanx of the first metatarsophalagic joint with the use of running socks
Authors: Carrión Álvaro Gómez , Medina José Manuel Reguera , Andueza Ignacio Ayerra , Jiménez Manuel Coheña , Cortés Juan Francisco Morán , Gómez Rubén Sánchez 
Published: July 2023

Abstract
The movement of the dorsal flexion of the first metatarsophalagic joint (MTPJ) is necessary for a correct gait. Its restriction generates an alteration in the establishment of the windlass mechanism, the Jack´s test allows to assess if there is alteration of movement. The use of compressive running socks is commonly used in the population, but we do not know how these socks influence the mechanism of windlass.Objectives: the aim of this study is to measure the amount of force needed to perform the dorsal flexion of the first MTPJ with the use of special compressive running socks.Methods: The sample size of this research was 30 subjects. Jack's test was measured with a new device, consisting of an algometer and a lever system. The necessary force was calculated with the use of two types of compressive running socks.Results: There were statistically significant differences with the use of special compressive running socks with orthopedic corrections during the Jack´s test measured with the new device(13.33N ±3.54, p<0.001).Conclusions: The use of special compressive running socks with orthopedic corrections decreases the force needed measured in Newtons to perform the dorsal flexion of the first MTPJ during the Jack´s test. The new device for measuring dorsal flexion of the first MTPJ is a valid and reliability tool.
The ta-C hardness effect on wear properties under MoDTC contained boundary lubrication
Authors: Tokoroyama T. , Wang S. , Umehara N. , Murashima M. , Lee W.-Y. 
Published: July 2023

Abstract
The wear acceleration of hydrogenated amorphous carbon under lubrication with molybdenum dithiocarbamate (MoDTC) is one of the problems to apply it to engine components. It is assumed that using high hardness tetrahedral amorphous carbon (ta-C) can easily solve the wear problem regardless of chemical wear by Mo degradable materials, however, we still do not know the effect of ta-C coating hardness on wear of itself with MoDTC. Because, amount and structure of Mo degradable material is assumed to relate contact pressure. It suggested that even if ta-C coating has high hardness, the wear amount changes with normal load. In this study, we prepared four different hardness ta-C coatings (such as approximately 18.2, 22.1, 46.6, and 53.6 GPa) and conducted friction tests to clarify the effect of ta-C hardness on wear characteristics under boundary lubrication with MoDTC. Eventually, chemical analysis (Raman, EDS and XPS) was conducted to reveal the chemical spices existence of tribofilm for three hardness ta-Cs, especially for 22.1 GPa as a representative low hardness ta-C coating. As a result, the wear suppression was achieved when the contact pressure was higher than 200 MPa regardless of the coating hardness.
FUS Unveiled in Mitochondrial DNA Repair and Targeted Ligase-1 Expression Rescues Repair-Defects in FUS-Linked Neurodegeneration
Authors: Hegde Muralidhar , Manohar Kodavati , Wang Haibo , Gao Wenting , Mitra Joy , Hegde Pavana , Provasek Vincent , Rao Vikas , Vedula Indira , Zhang Aijun , Mitra Sankar , Tomkinson Alan , Bosch Ludo Van Den , Hamilton Dale 
Published: July 2023

Abstract
This study establishes the physiological role of Fused in Sarcoma (FUS) in mitochondrial DNA (mtDNA) repair and highlights its implications to the pathogenesis of FUS-associated neurodegenerative diseases such as Amyotrophic lateral sclerosis (ALS). Endogenous FUS interacts with and recruits mtDNA Ligase IIIα (mtLig3) to DNA damage sites within mitochondria, a relationship essential for maintaining mtDNA repair and integrity in healthy cells. Using ALS patient-derived FUS mutant cell lines, a transgenic mouse model, and human autopsy samples, we discovered that compromised FUS functionality hinders mtLig3's repair role, resulting in increased mtDNA damage and mutations. These alterations cause various manifestations of mitochondrial dysfunction, particularly under stress conditions relevant to disease pathology. Importantly, rectifying FUS mutations in patient-derived induced pluripotent cells (iPSCs) preserves mtDNA integrity. Similarly, targeted introduction of human DNA Ligase 1 restores repair mechanisms and mitochondrial activity in FUS mutant cells, suggesting a potential therapeutic approach. Our findings unveil FUS's critical role in mitochondrial health and mtDNA repair, offering valuable insights into the mechanisms underlying mitochondrial dysfunction in FUS-associated neurodegeneration.