bluuebunny/crossref_metadata_2025_split huggingface dataset:
STUDI EKSPERIMEN PANEL SURYA DENGAN KOLEKTOR PEMANAS UDARA
Authors: Umar Mega Lazuardi , Wardana Prabuditya Bhisma Wisnu , Finali Asmar , Hanafi Agung Fauzi , Yaqin Rizqi Ilmal 
Published: April 2023

Solar panel is popular renewable energy technology because it is environmentally friendly, zero emissions, and environmentally clean. However, the energy conversion value from solar radiation to electricity is quiet small, more than 70% of solar radiation is discharged into heat energy. Therefore, a heat collector is needed to take advantage of the heat dissipation from solar panel. In this study, an air heat collector is placed at the bottom of the panel to indicating the potential energy, electrical efficiency and heat efficiency. It was found that solar panels with air heat collectors were able to increase the electrical efficiency of solar panels by 0.70%. The daily primary total energy efficiency value of solar panels with a heat collector is 17.47% higher than a solar panel without a collector. In the future, the results of this research can be a reference for academics and industry to develop their renewable energy potential.
Differentiation of Alzheimer’s Disease from Frontotemporal Dementia and Mild Cognitive Impairment Based on Arterial Spin Labeling Magnetic Resonance Imaging: A Pilot Cross-Sectional Study from PUMCH Dementia Cohort
Authors: Mao Chenhui , You Hui , Hou Bo , Chu Shanshan , Jin Wei , Huang Xinying , Shang Li , Feng Feng , Peng Bin , Gao Jing 
Published: April 2023

Background: Arterial spin labeling (ASL) is helpful in early diagnosis and differential diagnosis of Alzheimer’s disease (AD), with advantages including no exposure to radioactivity, no injection of a contrast agent, more accessible, and relatively less expensive. Objective: To establish the perfusion pattern of different dementia in Chinese population and evaluate the effectiveness of ASL in differentiating AD from cognitive unimpaired (CU), mild cognitive impairment (MCI), and frontotemporal dementia (FTD). Methods: Four groups of participants were enrolled, including AD, FTD, MCI, and CU based on clinical diagnosis from PUMCH dementia cohort. ASL image was collected using 3D spiral fast spin echo–based pseudo-continuous ASL pulse sequence with background suppression and a high resolution T1-weighted scan covering the whole brain. Data processing was performed using Dr. Brain Platform to get cerebral blood flow (ml/100g/min) in every region of interest cortices. Results: Participants included 66 AD, 26 FTD, 21 MCI, and 21 CU. Statistically, widespread hypoperfusion neocortices, most significantly in temporal-parietal-occipital cortices, but not hippocampus and subcortical nucleus were found in AD. Hypoperfusion in parietal lobe was most significantly associated with cognitive decline in AD. Hypoperfusion in parietal lobe was found in MCI and extended to adjacent temporal, occipital and posterior cingulate cortices in AD. Significant reduced perfusion in frontal and temporal cortices, including subcortical nucleus and anterior cingulate cortex were found in FTD. Hypoperfusion regions were relatively symmetrical in AD and left predominant especially in FTD. Conclusion: Specific patterns of ASL hypoperfusion were helpful in differentiating AD from CU, MCI, and FTD.
Adeno-Associated Virus-Mediated Immunotherapy Based on Bispecific Tandem scFv for Alzheimer’s Disease
Authors: Qian Lin , Bian Wenjuan , Wang Diqi , Ming Zhuoqun , Zhang Yu , Zhang Linbo , Fu Lu 
Published: April 2023

Background: Patients with Alzheimer’s disease (AD) have considerably increased globally as a result of population aging, placing a significant burden on the global economy and the medical system. The outcome of clinical trials for AD immunotherapy that solely targeted amyloid-β (Aβ) or phosphorylated tau protein (p-Tau) was unsatisfactory. Therefore, blocking both Aβ and p-Tau’s pathological processes simultaneously while also preventing their interaction may be the key to developing an effective AD therapy. Objective: To develop a novel immunotherapy based on bispecific tandem scFv (TaFv) against AD. Methods: Bispecific single-chain antibody that targets both Aβ and p-Tau were obtained using E. coli expression system. Biological ability of TaFvs were determined by ELISA, SDS-PAGE, and immunohistochemical assay. Recombinant adeno-associated virus 9 (rAAV9) were packaged to create TaFv. The in vivo activity of rAAV9 were detected in mouse, using biophotonic imaging and frozen section methods. Results: The outcomes demonstrated that both Aβ and p-Tau had a high affinity for the bispecific TaFv. Additionally, it can bind to the amyloid plaques and neuronal tangles in the brain slices of an AD mouse model. Moreover, the rAAV9 could infect neuronal cells, transverse the blood-brain barrier, and express TaFv in the mouse brain. Conclusion: This novel immunotherapy offers a fresh concept for the immunotherapy of AD and successfully delivers the double target antibody into the brain, acting on both pathogenic substances Aβ and p-Tau.
Association Between Serum Cystatin C and Cognitive Decline Independently from Creatinine: Evidence from Two Nationally Representative Aging Cohorts
Authors: Ma Yanjun , Li Chenglong , Hua Rong , Yang Chao , Xie Wuxiang , Zhang Luxia 
Published: April 2023

Background: Studies on the association between cystatin C based estimated glomerular filtration rate (eGFRcys) and cognitive outcomes yielded inconsistent results. Objective: The present study aimed to examine the potential association of eGFRcys with subsequent cognitive decline rate. Methods: A total of 11,503 community-based participants were involved in our analyses, including 5,837 (aged 72.9±6.3; 58.6% women) in the Health and Retirement Study (HRS) from the US and 5,666 (aged 58.1±9.2; 49.0% women) in the China Health and Retirement Longitudinal Study (CHARLS). The association of eGFRcys with subsequent cognitive decline rate was evaluated by linear mixed models. Results: During 85,266 person-years of follow-up, both baseline elevated serum cystatin C (–0.048 standard deviation [SD]/year per mg/L; 95% confidence interval [CI], –0.060 to –0.036; p < 0.001) and decreased eGFRcys (0.026 SD/year per 30 mL/min/1.73m2; 95% CI, 0.020 to 0.032; p < 0.001) were associated with faster cognitive decline rate after full adjustment. Compared with those had eGFRcys ≥90 mL/min/1.73m2, participants with eGFRcys between 60 to 90 mL/min/1.73m2 (–0.012 SD/year; 95% CI, –0.020 to –0.004; p = 0.004) and those with eGFRcys <60 mL/min/1.73m2 (–0.048 SD/year; 95% CI, –0.058 to –0.039; p < 0.001) experienced statistically significantly faster cognitive decline after adjustment. The associations were independent from serum creatinine/eGFRcre (eGFR that was calculated from serum creatinine). Conclusion: Decreased eGFRcys are significantly associated with faster cognitive decline after full adjustment, independently from serum creatinine/eGFRcre. Serum cystatin C might be a risk factor or a prodromal biomarker of cognitive decline.
StynMedGAN: Medical images augmentation using a new GAN model for improved diagnosis of diseases
Authors: Wali Aamir , Ahmad Muzammil , Naseer Asma , Tamoor Maria , Gilani S.A.M. 
Published: April 2023

Deep networks require a considerable amount of training data otherwise these networks generalize poorly. Data Augmentation techniques help the network generalize better by providing more variety in the training data. Standard data augmentation techniques such as flipping, and scaling, produce new data that is a modified version of the original data. Generative Adversarial networks (GANs) have been designed to generate new data that can be exploited. In this paper, we propose a new GAN model, named StynMedGAN for synthetically generating medical images to improve the performance of classification models. StynMedGAN builds upon the state-of-the-art styleGANv2 that has produced remarkable results generating all kinds of natural images. We introduce a regularization term that is a normalized loss factor in the existing discriminator loss of styleGANv2. It is used to force the generator to produce normalized images and penalize it if it fails. Medical imaging modalities, such as X-Rays, CT-Scans, and MRIs are different in nature, we show that the proposed GAN extends the capacity of styleGANv2 to handle medical images in a better way. This new GAN model (StynMedGAN) is applied to three types of medical imaging: X-Rays, CT scans, and MRI to produce more data for the classification tasks. To validate the effectiveness of the proposed model for the classification, 3 classifiers (CNN, DenseNet121, and VGG-16) are used. Results show that the classifiers trained with StynMedGAN-augmented data outperform other methods that only used the original data. The proposed model achieved 100%, 99.6%, and 100% for chest X-Ray, Chest CT-Scans, and Brain MRI respectively. The results are promising and favor a potentially important resource that can be used by practitioners and radiologists to diagnose different diseases.
Upaya Peningkatan Nilai Audit Operasional Dari Aspek Quality Di PT. Food Beverages Indonesia (Chatime) Menggunakan Metode Seven Tools
Authors: Rodiah Hj. , Aang Adi 
Published: April 2023

Semakin berkembangnya suatu perusahaan menuntut pula perkembangan di bidang pemeriksaan. Â PT. Food Beverages Indonesia (Chatime) adalah perusahaan yang bergerak dalam penjualan minuman buble tea, yang merupakan usaha yang bergerak di bidang jasa. Dalam pelaksanaan nya terdapat beberapa masalah yang mengharuskan perusahaan melakukan audit operasional.Penelitian ini bertujuan untuk mengidentifikasiÂ faktor-faktor yang menjadi penyebab menurun nya nilai audit, untuk mengetahui jumlah waste produk topping berada pada batas wajar, dan untuk mengetahui apa saja yang harus dilakukan agar nilai audit meningkat dengan menganalisis proses pembuatan topping-topping. Pada penelitian kualitas produk topping ini menggunakan tujuh alat pengendali mutu (seven tools). Seven tools meliputi : Diagram Alir (Flow Chart), Diagram Sebab Akibar (Cause and Effect Diagram), Lembar Periksa (Check Sheet), Histogram, Diagram Pareto, Diagram Pencar (Scatter Diagram), dan Peta Kendali (Control Chart). Data yang diambil yaitu data historis produksi bulan Mei 2018 sampai dengan April 2019 di PT. Food Beverages Indonesia.Dari data yang diambil terdapat banyak waste dalam satu tahun terakhir, namun masih dalam batas kendali karena apabila di rata-ratakan tidak ada yang melebihi batas toleransi waste yang ditentukan oleh Â PT. Food Beverages Indonesia, sebesar 2% dari total jumlah keseluruhan produksi. Berdasarkan hasil pengamatan, terlihat bahwa produk yang sering di waste di sebabkan karena produk tidak matang. Dengan data satu tahun terakhir waste dengan jumlah produk tidak matang mencapai 154.400 gram atau 93.3% dari total produksi. Â Kata Kunci : Pengendalian Kualitas, Audit Operasional, Seven Tools.
Perancangan Dan Realisasi Mesin Pengupas Bawang Merah
Authors: Ramdani Aliyudin , Munandar Ahmad 
Published: April 2023

Inovasi merupakan hal yang paling penting dikuasai di zaman persaingan teknologi yang serba canggih, karena dapat mempermudah segala jenis pekerjaan pada bidang apapun termasuk salah satunya bidang pertanian. Salah satu komoditas pertanian yang dihasilkan oleh negara Indonesia adalah bawang merah. Salah satu inovasi yang dapat membantu petani untuk mengolah bawang merah ialah mesin pengupas bawang merah. Mesin pengupas bawang merah yang akan dibuat menggunakan kawat loket, plat stainless steel 304, plat besi, besi siku, poros danÂ menggunakan motor listrik dengan penggerak puli lalu ditransmisikan menggunakan V-belt dengan daya 0,5 hp, dimana proses pembuatanya menggunakan proses permesinan, pengelasan, dan kerja bangku. Mesin pengupas bawang merah ini mempunyai kapasitas maksimum 7,5 kg/proses dengan putaran tabung 1420 rpm. Dengan waktu pengujian sekitar 30 menit mesin dapat menghasilkan 90% bawang merah terkupas dari kapasitas maksimum mesin.
Hubungan & Pengaruh Antara Review Product Terhadap Keputusan Pembelian Produk Skincare di E-Commerce Shopee
Authors: Aziz Fikri Nur , Munandar Ahmad 
Published: April 2023

Kesempurnaan diri merupakan faktor yang cukup penting dalam menompang penampilan salah satunya dengan menggunakan skincare. Banyak konsumen yang membeli suatu produk menggunakan e-commerce salah satunya pembelian produk skincare. Maka dirasa penting untuk mengetahui review product sebelum konsumen membeli. Penelitian ini dimaksudkan untuk mengetahui pengaruh Review Product terhadap keputusan pembelian produk skincare di e-commerce shopee di wilayah kelurahan sarijadi menggunakan metode Analisis Regresi Sederhana dengan mengambil 245 responden dari populasi berjumlah 1.972 jiwa sebagai sampel penelitian. Dari hasil analisa data menunjukan arah positif, maka terdapat pengaruh yang signifikan secara parsial antara Review Product terhadapÂ keputusan pembelian. Derajat kedekatan, suatu relasi yang terjadi antara variabel diperoleh nilai sebesar r= 0,691. Nilai ini menunjukan hubungan yang kuat antara Review Product(X) dan Keputusan Pembelian(Y).
FUNDAMENTAÇÃO TEÓRICA PARA PROFESSORES NA ÁREA DE HISTÓRIA E FILOSOFIA DA BIOLOGIA: CONHECENDO OS ASPECTOS TEMÁTICO-AUTORAL DE UM PERIÓDICO DA ÁREA
Authors: Barbosa Gabriel da Rocha , Martins Iury Kesley Marques de Oliveira , Guimarães Simone Sendin Moreira 
Published: April 2023

O objetivo deste artigo é apresentar um mapeamento quali-quantitativo das produções publicadas no periódico Filosofia e História da Biologia entre 2006 (ano da primeira publicação) e 2019 (migração do site para outra plataforma), caracterizando especialmente a formação dos autores e lugar geográfico de atuação bem como as temáticas recorrentes na publicação. Metodologicamente consideramos elementos da Revisão Sistemática para o levantamento dos artigos e a análise foi pautada pela perspectiva dialética. Constatou-se no mapeamento que os autores que publicam na revista são formados em biologia (66%) e tem como local geográfico de atuação o Sudeste (59%). Também é possível que sejam os responsáveis pelo coletivo mais relevante relacionado ao tema no Brasil. Em relação à análise temática, os conceitos relacionados à Teoria da Evolução aparecem na maior parte dos artigos publicados (38%) prevalecendo uma visão de mundo histórica (46%). Destaca-se a necessidade de mais pesquisas a partir do periódico, haja vista seu potencial para o desenvolvimento do campo de investigação relacionadas a história e filosofia da biologia no Brasil bem como para fundamentação de professores e professoras de biologia que atuam na educação básica.
Palavras-chave: História da Biologia. Levantamento temático. Periódico científico. Teoria da Evolução.

ABSTRACT
The objective of this article is to present a qualitative and quantitative mapping of the productions published in the journal Philosophy and History of Biology between 2006 (year of first publication) and 2019 (migration of the site to another platform), characterizing especially the training of the authors. and geographical place of action, as well as recurring themes in the publication. Methodologically, we considered elements of the Systematic Review to survey the articles and the analysis was guided by the dialectical perspective. It was found in the mapping that the authors who publish in the journal are trained in biology (66%) and have the Southeast (59%) as their geographic location. It is also possible that they are responsible for the most relevant collective related to the topic in Brazil. Regarding the thematic analysis, concepts related to the Theory of Evolution appear in most published articles (38%) with a prevailing historical worldview (46%). The need for more research based on the journal is highlighted, given its potential for the development of the field of investigation related to the history and philosophy of biology in Brazil, as well as for the foundation of biology teachers who work in basic education.
Keywords: History of Biology. Thematic survey. Scientific journal. Evolution theory.
PENGARUH INFLASI, SUBSIDI BBM, DAN ANGGARAN INFRASTRUKTUR TERHADAP PERTUMBUHAN EKONOMI
Authors: Nuswandari Inti , Wibowo Edi , Indiarti Miralda 
Published: April 2023

Ada beberapa faktor yang bisa mempengaruhi laju “pertumbuhan ekonomi di Indonesia”. Penelitian ini menganalisis pengaruh inflasi, subsidi BBM, dan anggaran infrastruktur terhadap pertumbuhan ekonomi. Ketiga komponen ini memiliki peranan penting di dalam pergerakan pertumbuhan ekonomi nasional. Tujuan dari penelitian ini adalah unuk mengetahui pengaruh atas inflasi, subsidi BBM dan anggaran infrastruktur terhadap tingkat pertumbuhan ekonomi Indonesia. Penelitian yang dilakukan menggunakan pendekatan ekonometrika dalam bentuk model sistem persamaan simultan yang variable bebasnya adalah inflasi, subsidi BBM, anggaran infrastruktur sementara pertumbuhan ekonomi Indonesia sebagai variable terikatnya. Hasil penelitian melalui uji t menyatakan bahwa ketiga variable yang merupakan variable bebas tersebut secara terpisah memiliki pengaruh signifikan terhadap variable terikat. Dari Uji F didapatkan pula bahwa ketiga variable bebas tersebut secara bersama-sama memberikan pengaruh terhadap variabel terikat. Berdasarkan penelitian yang dihasilkan ini diharapkan dapat menjadi acuan atau referensi dalam pengambilan kebijakan-kebijakan terkait perekonomian Indonesia. Pemerintah, dalam hal ini sebagai penyelenggara negara diharapkan mampu membuat kebijakan yang mendorong peningkatan pertumbuhan perekonomian yang berimplikasi pada peningkatan kesejahteraan masyarakat. Kebijakan pengendalian inflasi, kebijakan subsidi serta kebijakan anggaran harus terus didorong ke arah tercapainya pertumbuhan ekonomi yang berkesinambungan. Kata kunci: bahan bakar minyak (BBM), inflasi, infrastruktur, pertumbuhan ekonomi There are several factors that can affect the rate of economic growth in Indonesia. This study analyzes the effect of inflation, fuel subsidies, and infrastructure budget on economic growth. These three components have an important role in the movement of national economic growth. This study has purpose to determine the effect of inflation, fuel subsidies and infrastructure budget on Indonesia's economic growth rate. The study was built using the econometric approach in the form of a simultaneous equations model consisting of inflation, fuel subsidies, the infrastructure budget as the independent variable and Indonesian Economic Growth as the dependent variable. The results of the study stated that the three independent variables have an influence on the dependent variable. Based on the results of this study, it is expected to be a reference in making policies related to the Indonesian economy. The government, as the state administrator is expected to be able to make policies that encourage the increased of economic growth which has implications for improving people's welfare. Inflation control policies, subsidy policies and budget policies must continue to be encouraged towards achieving sustainable economic growth. Keywords: economic growth, fuel, inflation, infrastructure
PENGARUH STRESS KERJA, LINGKUNGAN KERJA, DAN KOMITMEN TERHADAP NIAT UNTUK BERPINDAH DI PT UNIFLEX KEMASINDAH
Authors: Agustina Alvi Puguh , Setyaningrum Retno Purwani 
Published: April 2023

Tujuan penelitian ini meneliti pengaruh stres kerja terhadap turnover intention, pengaruh lingkungan kerja terhadap turnover intention, dan pengaruh komitmen organisasi terhadap turnover intention di PT Uniflex Kemasindah. Adapun metodenya adalah mengumpulkan data melalui kuesioner yang disebar ke 67 responden dan sampel menggunakan sampel jenuh. Metode analisis data dengan Smart PLS 3.3.3 dengan outer model, inner model, dan uji hipotesis. Hasil analisis menyatakan stres kerja berpengaruh signifikan terhadap turnover intention, lingkungan kerja tidak berpengaruh terhadap turnover intention, dan komitmen organisasi berpengaruh signifikan terhadap turnoverintention. Nilai R-square sebesar 0.429 atau 42.9% yang berarti turnover intention dipengaruhi oleh stres kerja, lingkungan kerja, dan komitmen organisasi sebesar 42.9% , sisanya 57.1% dipengaruhi dengan variable lain diluar penelitian ini. Kata kunci: : komitmen organisasi, lingkungan kerja, stres kerja, turnover intention ABSTRACT The purpose of this study is to determine the effect of work stress on turnover intention, the effect of the work environment on turnover intention, and the effect of organizational commitment on turnover intention at PT Uniflex Packaging. The method used for data collection was a questionnaire distributed to 67 respondents and the sampling method used a saturated sample. The data analysis method utilized SmartPLS 3.3.3 with the outer model, inner model and hypothesis testing. The results of the analysis show that work stress has a significant effect on turnover intention, the work environment has no effect on turnover intention, and organizational commitment has a significant effect on turnover intention with an R-square value of 0.429 or 42.9% which means that turnover intention is influenced by work stress, work environment and organizational commitment of 42.9%, while the remaining 57.1% is influenced by other variables outside of this study. Keywords: commitment organization, work environment, work stress, turnover intention
MENGUJI MEMORABLE TOURISM EXPERIENCES TERHADAP NIAT KUNJUNG ULANG WISATAWAN PADA GEOPARK DI KEBUMEN
Authors: Riptiono Sulis 
Published: April 2023

Memorable tourism experiences telah menjadi konsep yang penting dalam pemasaran wisata khususnya menumbuhkan niat pengunjung untuk berkunjung ulang. Makadari itu, tujuan penelitian ini adalah untuk menguji pengaruh dimensi-dimensi MTE’s terhadap niat berkunjung ulang pada Geopark Karangsambung di Kebumen. Studi ini melibatkan sebanyak 100 wisatawan yang berkunjung pada objek wisata tersebut. Tehnik pengambilan sample yang digunakan dengan convenience sampling. Data yang terkumpul diolah dengan menggunakan SPSS versi 28 dan dianalisis menggunakan analisis regresi berganda. Hasil penelitian menunjukkan bahwa dari ketujuh variable dari MTE’s, terdapat empat variable yang diterima dan tiga variable yang ditolak. Local culture, knowledge, involvement, dan novelty secara signifikan terbukti berpengaruh pada revisit intention. Sedangkan hedonism, refreshment, dan meaningfulness tidak terbukti memberukan pengaruh pada revisit intention. Novelty merupakan variable yang memiliki pengaruh terbesar bagi niat wisatawan untuk melakukan kunjungan ulang pada Geopark Karangsambung. Kata kunci: geopark, memorable tourism, niat kunjung ulang, pemasaran wisata, pengalaman ABSTRACT Memorable tourism experiences have become an important concept in tourism marketing, especially in cultivating visitor intentions to revisit. Therefore, the purpose of this study was to examine the effect of MTE's dimensions on intention to return to the Karanggulung Geopark in Kebumen. This study involved as many as 100 tourists who visited the tourist attraction. The sampling technique used is convenience sampling. The collected data were processed using SPSS version 28 and analyzed using multiple regression analysis. The results showed that of the seven variables from MTE's, there were four variables that were accepted and three variables that were rejected. Local culture, knowledge, involvement, and novelty are significantly proven to have an effect on revisit intention. Meanwhile, hedonism, refreshment, and meaningfulness are not proven to have an effect on revisit intention. Novelty is the variable that has the greatest influence on tourist intentions to make a repeat visit to the Karanggulung Geopark. Keywords: experiences, geopark, marketing tourism, memorable tourism, revisit intention