bluuebunny/crossref_metadata_2025_split huggingface dataset:
Immunomodulatory effect of a proprietary polyherbal formulation on healthy participants: A single- blind, randomized, placebo- controlled, exploratory clinical study
Authors: Khadke Suresh , Gupte Poonam , Mourya Akanksha , Yadav Amit , Mane Sarika , Joshi Asavari , Mahajan Madhavi , Mishra Manisha , Bhalerao Supriya 
Published: July 2023

Context:
Clinical study for immunity.

Aims:
The present study aimed to assess the effect of proprietary polyherbal formulation (PPHF), labelled as Kofol immunity tablets (KIT) on innate and adaptive immune responses in healthy individuals, on the backdrop of COVID-19 pandemic.

Settings and Design:
Single-blind, randomized, placebo-controlled, exploratory study in institutional setting.

Materials and Methods:
Post Ethics Committee permission, screened healthy individuals of either sex aged 18–35 years were randomized to PPHF/Placebo for 2 months. Major assessment variables included peak expiratory flow rate (PEFR), questionnaire-based immune status, perceived stress, and quality of life (QOL) with immune-specific cell counts (CD4+, CD8+), cytokines (interferon gamma [IFN-γ], tumor necrosis factor-alpha [TNF-α], interleukin 10 [IL-10]), and oxidative stress in red blood cells (RBCs) (malondialdehyde (MDA), glutathione peroxidase [GPx]), done at day 60.

Statistical Analysis Used:
Mean ± standard deviation and paired/unpaired t-test for parametric data analysis while median (range) and Wilcoxon Rank sum test/Mann–Whitney test for nonparametric data analysis, were done. Categorical data was analyzed using Chi-square test. GraphPad InStat software, version 9 was used with p < 0.05, as the level of statistical significance.

Results:
Of 52 recruited, 28 individuals completed the study. PPHF significantly increased PEFR, improved immune status along with QOL compared to baseline. It also decreased perceived stress from moderate and severe grade to mild. Serum IFN-γ levels remained almost constant post-PPHF treatment. PPHF significantly decreased MDA and increased GPx in RBCs. Significant decrease and increase in TNF-α and IL-10, respectively, were seen in PPHF group. The safety parameters post-PPHF treatment remained within normal reference ranges.

Conclusions:
PPHF is an efficacious and safe formulation with immunomodulatory potential.
Post-approval process: A challenge for ethics committees
Authors: Halwai Aarti , Vaswani Vina 
Published: July 2023

Context:
Ethics committees (ECs) work toward upholding rights, dignity, safety, and well-being of research participants. They are also tasked with conducting oversight pre- and post-approval. ECs face various challenges in their functioning. Post-approval oversight is one of the major challenges, and various studies have stressed the importance of post-approval oversight.

Aims:
The aim of this study was to explore the challenges in the post-approval processes that are faced by the ECs and to suggest solutions to the most common challenges.

Methods:
We conducted a quantitative study contacting member secretaries of different ECs using an online Google Forms questionnaire. The questionnaire consisted of three domains and included questions about the description of the EC, conduct of post-approval activities, and challenges encountered during the post-approval process.

Results and Conclusion:
We received responses from 61 member secretaries. We were able to identify challenges faced by the EC members in the post-approval process in the areas of site monitoring visit, review of post-approval submission (nonsubmission/incomplete submission/late submission of documents by PI, long time taken by reviewers, nonavailability of reviewers, nonadherence to timeline and too much paperwork), review of serious adverse events, and review of protocol deviations. Our study also noted the difference between accredited/assessed (National Accreditation Board for Hospitals and Healthcare Providers/Forum for Ethical Review Committees in the Asian and Western Pacific Region) ECs versus registered (Central Drugs Standard Control Organisation/Department of Health Research only) ECs by comparing the challenges.
Arte de frontera: lo migratorio, siniestro y psicopatológico en la pintura de Martín Ramírez
Authors: Gómez-Vargas Christian Guillermo 
Published: July 2023

El texto tiene la finalidad de plantear algunas relaciones entre la función del arte, en su modalidad terapéutica, ante la psicopatología ―con el trasfondo de la categoría de lo siniestro―, desde una perspectiva psicoanalítica y estética. Específicamente, se aborda el caso de la obra de Martín Ramírez, pintor mexicano que vivió gran parte de su vida recluido en hospitales psiquiátricos de Estados Unidos (desde la década de los treinta del siglo pasado). La experiencia de Ramírez alude a la pérdida de la razón desde una situación de migrante; este se halla completamente desterritorializado, ya que nunca aprendió a hablar inglés. Así, su diagnóstico ―para algunos autores― se realizó de manera errada, estuvo influenciado por el racismo: algunos medios psiquiátricos consideraban a los migrantes como potenciales portadores de locura, lo cual ponía en peligro las condiciones genéticas de los americanos para futuras generaciones. El arte, para Ramírez, opera como un dispositivo atemperador frente a las dinámicas biopolíticas del hospital psiquiátrico, debido a que con este intenta reconstruir un horizonte de coherencia y sentido ante las realidades psíquicas (interiores) y exteriores (fenoménicas) que se han colapsado. Empero, el arte funge como un mecanismo de compensación frente a un principio de realidad que se ha diluido, tal como para algunos autores funcionan los mecanismos de compensación psíquicos, como sucede en el caso de la psicosis. Entonces, se abre una veta para el tratamiento de psicopatologías, allende una terapéutica de corte farmacológico de cuño neurobiológico positivo.
madre monstruosa: figuraciones de la casa y de la maternidad en Mandíbula de Mónica Ojeda
Authors: Garnica-Brocos Helen 
Published: July 2023

La novela Mandíbula (2018) de Mónica Ojeda da cuenta de una configuración que se puede reconocer monstruosa en torno a la figura materna desde, principalmente, dos aristas: la gestación de la madre como un ser que devora y ahoga a sus crías (homologación con una matriz violenta) y la extrañificación mediante una representación animalizada que carece de referentes humanos y se muestra semejante a elementos del reino animal y vegetal, o tópicos hórridos como la noción de la bruja. En ese sentido, nuestra investigación se detendrá en las imágenes vinculadas a los espacios domésticos que representan figuraciones disruptivas para la profesora Clara, y las estudiantes Annelise y Fernanda. Para ello, ubicaremos la casa-útero que se constituye símil de un cuerpo femenino que las hijas simultáneamente anhelan y repelen. Así, nos valdremos, principalmente, de la categoría de monstruo trazada por Mabel Moraña en El monstruo como máquina de guerra (2017) y por Elena del Río en Una era de monstruos. Representaciones de lo deforme en el Siglo de Oro español (2003), puesto que nos servirá para detectar fisuras dentro del discurso racional y la emergencia de una filiación distinta. De manera similar, señalaremos los peligros que conlleva una cercanía malsana para la progenie basándonos en los artículos de Luce Irigaray (1994) y de Jacques-Alain Miller (2005).
Trabajo, institución y salud mental
Authors: Maureira-Silva Sergio 
Published: July 2023

La relación entre trabajo, institución y salud mental es un tema de relevancia en Chile, a propósito del interés por comprender la relación entre las enfermedades laborales asociadas a los efectos no cuantificables e invisibilizados por los modelos de objetivación del malestar, que han sido muchas veces dominio del higienismo, la ergonomía, la salud ocupacional y la psicología organizacional. Estas modalidades de comprensión establecen conceptos, representaciones sociales y estrategias de intervención en las mutualidades, las instituciones y en la ciudadanía, que muchas veces reducen el sufrimiento y su abordaje a cambios en la infraestructura, materiales, técnicas, conflictos intrapsíquicos, familiares o patologías de salud mental aisladas del contexto laboral.
Zihinsel İş Yükü ile Tükenmişlik Arasındaki İlişki: Sağlık Çalışanları Örneği
Authors: KARACA Beşir Rıdvan , OĞUZHAN Gülpembe 
Published: July 2023

Amaç: Sağlık çalışanlarının zihinsel iş yükü düzeylerini tespit etmek ve tükenmişlik düzeyleri ile olan ilişkisini incelemektir.
Gereç ve Yöntem: Araştırmanın evreni olarak Samsun ilinde bir dal hastanesinde görev yapmakta olan 124 sağlık çalışanı alınmış ve 101 sağlık personeline anket uygulanmıştır. Anket olarak zihinsel iş yükü düzeyini belirlemek amacıyla Ulusal Havacılık ve Uzay Kurumu İş Yükü İndeksi (National Aeronautics and Space Administration Task Load Index-NASA-TLX), tükenmişlik düzeyini belirlemek için ise Maslach Tükenmişlik Envanteri kullanılmıştır.
Bulgular: Duygusal tükenmenin hekimlerde 3.25, fizyoterapistlerde ise 3.11 ile “yüksek” eşik değeri olan 3 ortalamanın üstünde olduğu ortaya çıkmıştır. Zihinsel iş yükü ortalaması ise; hekimlerde 76.25, fizyoterapistlerde 76.93, hemşirelerde 70.67 ve diğer sağlık personelinde 64.73 olarak hesaplanmıştır. Zihinsel iş yükü ile duygusal tükenme arasında pozitif yönlü zayıf düzey anlamlı bir ilişki bulunmuştur (r=0.272, p=0.006). Ancak zihinsel iş yükünün duyarsızlaşma ve kişisel başarı düzeyi ile arasında anlamlı bir ilişki bulunamamıştır.
Sonuç: Sağlık çalışanlarının zihinsel iş yükü düzeyinde meydana gelen artış duygusal tükenme düzeyini de artırmaktadır. Ayrıca zihinsel iş yükü düzeyi ve tükenmişlik düzeyi sağlık çalışanlarının mesleklerine göre farklılıklar gösterebilmektedir.
Effect of NIC Interventions to Older Adults on Behaviour Regarding Drug Use and Drug Response: Quasi-Experimental Study
Authors: GENÇBAŞ Dercan , DARICI Zeynep Kübra , BEBİŞ Hatice 
Published: July 2023

Aim: This study aims to investigate the effect of ‘teaching: prescribed medication’ NIC on drug use behaviors and ‘medication response’ NOC outputs of older people.
Material and Methods: This study was designed with a quasi-experimental form. The Patient Information Form, Questionnaire of Elderly Drug Use Behaviours, and ‘Medication Response’ NOC Scale were applied to older adults who were admitted to Internal Medicine Clinic and complied with the research criteria. After applying the forms, ‘teaching: prescribed medication’ NIC interventions were applied to each of the older adults.
Results: After the ‘teaching: prescribed medication’ NIC intervention was applied to the older adults, the drug adherence behavior and patient outputs after drug use changed positively (p
Türkiye’de İlişkisel Travmaların Kuşaklar Arası Aktarımını İnceleyen Lisansüstü Tezlerin İncelenmesi
Authors: ÇİYDEM Emre , KAÇKİN Özlem 
Published: July 2023

Amaç: Bu çalışmanın amacı Türkiye’de ilişkisel travmaların kuşaklar arası aktarımını inceleyen lisansüstü tezlerin içerik analizi yöntemiyle incelenmesidir.
Gereç ve Yöntem: Betimsel tarama modelindeki araştırmanın örneklemini 12 lisansüstü tez oluşturmuştur. Ulusal tez merkezinin gelişmiş tarama sekmesi üzerinden 1990-2022 arasında yayınlanan tezler kuşaklararası, kuşak, nesil, arası, aktarım, geçiş, travma, üç kuşak, iki kuşak kelimelerinden oluşan kombinasyonlar kullanılarak taranmıştır. Veri toplama aracı olarak Bilgi Formu kullanılmıştır. Veriler betimsel içerik analizi yöntemi kullanılarak analiz edilmiştir.
Bulgular: Tezlerin %41.7’sinin 2019 yılında, %66.7’sinin yüksek lisans tezi olarak yürütüldüğü belirlenmiştir. Tezlerin araştırma tasarımı olarak %50’sinin nicel, %33.3’ünün nitel, %16.7’sinin ise karma yöntem kullandığı belirlenmiştir. Tezlerin %41.7’sinin amaçlı örnekleme yöntemini, diğer %41.7’sinin ise kartopu örnekleme yöntemini kullandığı belirlenmiştir. Tezlerde yapısal eşitlik, t testi, ANOVA ve tema analizi gibi çeşitli istatiksel analiz yöntemlerinin kullanıldığı belirlenmiştir. Karma yöntem çalışmalarının bazılarında entegrasyon yeterince sağlanamamıştır.
Sonuç: Tezlerde farklı örnekleme ve istatiksel analiz yöntemlerinin kullanıldığı ve çalışmalardan birinde entegrasyonun yeterince sağlanamadığı belirlenmiştir.
Pengaruh Kepemimpinan dalam Peningkatan Motivasi Kerja PNS di Kantor Kecamatan
Authors: Akhmad Zaenal , Hasran Hasran , Rahman Rahman 
Published: July 2023

Abstract
This study aims to determine the influence of sub-district leadership on increasing the work motivation of civil servants in Bontomatene District, Selayar Regency. This research was conducted in the area of ​​the Bontomatene District Office, Selayar Regency. In this study the authors used a survey research basis. While the type of research used was to obtain research data, the population used by the author was all employees of the Bontomatene District office, Selayar Regency, while the informants were the Bontomatene Sub-District Head and the Bontomatene Sub-District Secretary. The sampling technique in this study is the purposive sample method. To collect the required data the author collects data through: Library research, field research, interviews, questionnaires and online data tracking. The collected data will be analyzed using a qualitative approach. The results of the research show that the leadership of the sub-district head which influences employee motivation seen from planning is quite good. This can be seen with an average score of 2.2 which shows that the planning carried out by the Bontomatene Sub-District Head is in the moderate category. All employees have been involved in planning the sub-district work program, but the resulting score is still in the moderate category. Therefore, employee involvement still needs to be improved. In addition to planning indicators, researchers also use indicators of effective communication. The communication carried out by the Bontomatene sub-district head to his subordinates still needs to be improved.
Analisis Rencana Pelaksanaan Pembelajaran (RPP) untuk Implementasi Kurikulum 2013 di Madrasah Tsanawiyah Negeri Binjai
Authors: Arlina Arlina , Sanjuwatma Delvi , Sari Nur Awaliyah Afrinda , Rizki Juan Adji 
Published: July 2023

The problems faced by teachers in developing lesson plans are that they have not been equipped with KI-1 and KI-2 on indicators and teachers have not revised several lesson plans according to Permendikbud Number 103 of 2014. Therefore this study aims to (1) describe teachers' opinions regarding lesson plans for curriculum implementation 2013, (2) describes the suitability of the contents of lesson plans developed by teachers with the implementation of the 2013 curriculum, (3) describes the constraints faced by teachers in developing lesson plans for implementing the 2013 curriculum, and (4) describes the efforts made by teachers in overcoming problems in developing RPP for implementing the 2013 curriculum. This type of research is descriptive research. The subjects in this study were 3 low grade teachers. Data collection methods used in this study, namely questionnaires, observations and interviews. The collected data was processed using quantitative descriptive analysis techniques and qualitative descriptive analysis. The results showed that (1) the teacher's opinion regarding lesson plans (2) the suitability of the content of lesson plans developed by teachers with the implementation of the 2013 curriculum (3) the obstacles faced by teachers in developing lesson plans were that teachers had difficulty designing learning steps in core activities because they were too much guided to observing, and (4) teacher problems in developing lesson plans can be overcome by filling oneself in by adding insight through workshop activities related to the implementation of the 2013 curriculum, being responsive to information and often sharing information related to the 2013 curriculum with other teachers and with the school principal.
Keywords: RPP, curriculum 2013
Peran Guru PAI Dalam Membentuk Karakter Islami Siswa MAS Al-Wasliyah Tembung
Authors: Siagian Fitri Alkomariah , Harahap Nur Fauziah , Muliadi Muliadi , Rahayu Widia , Audrie Fiona Shopie , Arlina Arlina 
Published: July 2023

The role of Islamic religious education (PAI) teachers cannot be overstated in shaping the identity of Muslim students in formal education settings such as schools and mosques; this article, in particular, draws attention to the contributions of Guru Aqidah Akhlak. Because of the role of the Aqidah Akhlak teacher as a role model, role model, and idol for his students, it is hoped that they can be formed into Muslims through pedagogical techniques which are usually in the form of lectures and reprimands. The purpose of this study was to find out (1) how much influence the Aqidah Akhlak curriculum had in shaping the Islamic identity of MAS Al-Wasliyah Tembung students. (2) Analyze the supporting and inhibiting factors encountered in implementing Islamic reform. 3. Study the responses of MAS Al-Wasliyah Tembung students. How big is the change before and after MAS Al-Wasliyah Tembung students shape their Islamic character profile? This study uses a quantitative descriptive research design. Data collection through interviews, observation, and written notes. Next, a descriptive quantitative analysis was carried out by providing the relevant data set. The results showed that the role of Islamic religious education teachers, especially teachers of Islamic religious beliefs in shaping the Islamic character of MAS Al Wasliyah students, was as a guide, educator, leader, and motivator. . Students at MAS Al-Wasliyah Tembung are expected to develop a peaceful, virtuous character by participating enthusiastically in religious education lessons — classes which usually involve reciting and reciting the Koran, as well as discussing its meaning with a qualified teacher, or 'Gurus Tahfiz. .
Keywords: The Role of Islamic Education Teachers, Islamic Character.
Bakti Kami Pejuang Muda Kementerian Sosial Kabupaten Lamongan
Authors: Zulia Anita , Adrinoviarini Adrinoviarini 
Published: July 2023

Bakti kami pejuang muda kementerian sosial di kabupaten lamongan merupakan salah satu program dari peserta pejuang muda kabupaten lamongan dari kementerian sosial, dan mahasiswa akan dituntut untuk mengaplikasikan ilmu dan pengetajuannya dapat memberikan dampak sosial secara konkret melalui program setara 20 SKS ini, mahasiswa akan ditantang untuk belajar dari warga sekaligus berkolaborasi dengan pemerintah daerah, pemuka masyarakat, tokoh agama setempat serta seluruh stakeholder penggerak sosial di daerah.
Program pejuang muda adalah kesempatan emas bagi mahasiswa untuk membuat perubahan nyata di masyarakat kementerian sosial diperkuat brand ambassador untuk mempromosikan program ini melalui cerita mengenai program pejuang muda di media sosial mereka, program pejuang muda berpegang pada nilai yang relevan untuk perkembangan mahasiswa dan perubahan sosial di masyarakat.
Pendampingan Literasi Keuangan Digital Bagi UMKM Digital Di Kelurahan Tembong Kota Serang
Authors: Rahmiyanti Sev , Arianto Bambang 
Published: July 2023

Era digitalisasi membuat pemanfaatan aplikasi keuangan digital dapat berkontribusi bagi pengembangan bisnis UMKM terutama dari aspek keuangan. Para pegiat UMKM sejatinya bisa mempergunakan kemajuan teknologi keuangan digital untuk pembiayaan dan penguatan modal bisnis. Akan tetapi minimnya literasi keuangan digital membuat para pegiat UMKM terutama berbasis digital tidak bisa mempergunakan layanan keuangan digital dengan baik, sehingga justru banyak yang terkena pinjaman online ilegal. Dalam pengabdian masyarakat di Kelurahan Tembong Kota Serang yang dilaksanakan pada tanggal 5 Maret 2023, telah diberikan pendampingan tentang pentingnya literasi keuangan digital bagi pegiat UMKM berbasis digital. Dari hasil kegiatan ini diketahui bahwa para pegiat UMKM masih rendah pemahaman terkait literasi keuangan digital. Hal itu yang membuat beberapa pegiat UMKM digital sulit berkembang dan justru memperburuk kinerja bisnis. Keberhasilan kegiatan ini tampak dari para pegiat UMKM digital yang telah memanfaatkan berbagai aplikasi keuangan digital bagi peningkatan modal kerja melalui pola pembiayaan keuangan digital. Para pegiat UMKM juga dapat mengenal tata kelola keuangan digital, sehingga bisa melakukan transaksi digital sebagai upaya memperkuat aspek keuangan dan ekosistem bisnis digital.
Semarak Masyarakat Desa Sasak Panjang Pada Perayaan Hari Kemerdekaan
Authors: Latifah Latifah , Yudiana Yudi 
Published: July 2023

Perayaan hari kemerdekaan merupakan refleksi wujud syukur masyarakat atas kemerdekaan. Pada prakteknya bentuk perayaan seringkali dicederai dengan kegiatan yang justru menodai nilai kemerdekaan itu sendiri. Desa Sasak Panjang kecamatan Tajurhalang Bogor merupakan salah satu desa yang memiliki luas wilayah yang cukup besar, serta di huni oleh penduduk yang berasal dari berbagai daerah berbeda di Indonesia. Keberagaman latar belakang asal penduduk di desa ini tentu saja perlu dibina dan dijaga rasa kebersamaannya. Pada kenyataannya kita masih banyak mendengar berita negatif terjadinya tawuran antar daerah, pengkubuan satu etnik asal daerah tertentu merasa lebih superior dibandingkan daerah lain, penguasaan wilayah atau lahan oleh suatu kubu wilayah tertentu dsb. Salah satu langkah antisipasipatif yang dilakukan oleh pemerintahan desa Sasak Panjang adalah penyelenggaraan perayaan pestival karnaval, karena didalamnya terkandung makna, arti dan nilai penting dalam mempersatukan bangsa serta menumbuhkembangkan tingkat kreativitas dengan melibatksan seluruh kalangan umur masyarakat maupun mahasiswa yang sedang melaksanakan Kuliah Kerja Nyata.
Endovascular treatment for ruptured aortic aneurysm complicating hemoptysis
Authors: Anh Vo Tuan , Anh Pham Minh , Nguyen Nguyen Thoi Hai , Phuoc Dang Ha Huu 
Published: July 2023

Introduction: Aortic disease has a high mortality rate, especially when complications include - hemoptysis. Treatment includes surgery and endovascular intervention with its own advantages and disadvantages. Endovascular intervention is associated with good early and medium-term outcomes.
Subjects – Methods: We report 03 cases of hemoptysis due to ruptured thoracic aortic aneurysm who underwent endovascular intervention at Dong Nai General Hospital.
Result: In all three cases, endovascular grafts were placed in the descending thoracic aorta, the number of grafts used was 1, the time to stop hemoptysis was 4-5 days, the hospital stay was from 6 to 8 days. No intravascular fistula was noted in the three patients. There were no cases of premature death, renal failure, prolonged mechanical ventilation and other major cardiovascular events.
Conclusion: The implementation of this technique at regional hospitals helps to improve prognosis, reduce mortality and complications, and contributes to improving the quality of hospital expertise. (consider: contributes to improving the quality of hospital expertise.)