bluuebunny/crossref_metadata_2025_split huggingface dataset:
Variances of life expectancy estimations
Authors: Dang Phuc Ho , Nguyen Thanh Nga 
Published: April 2023

Abstract
Concerning the local parametric estimation method, a novel method of life expectancy estimation, the article derives a formula to calculate the variance of that estimation. Specifically, we provide the theoretical base of the variance formula, then prove the approximation to normal distribution of the life expectancy local parametric estimation. Extensive experiments with real-world datasets show that the local parametric method provides less biased estimation with lower variance in comparison to the Chiang method. This confirms the advantages of the new life expectancy estimation method over the Chiang estimation method. The lower variance of estimation allows the statistical tests to get the higher performance in detection of life expectancy estimation differences. The new life expectancy estimation method can be useful in the assessment of the health inequality in small area settings by conducting statistical tests.
Effect of operative positions during bariatric surgery on postoperative nausea and vomiting
Authors: Li zhaopeng , Song Yancheng , Tian Yaoyao , Li Yali , Yang Xiaojuan , Zhou Xia , Li Zhao , Liu Shuguang , Li Yu 
Published: April 2023

Abstract
Objective To explore the effect of operative positions during bariatric surgery on postoperative nausea and vomiting(PONV) .Methods The patients with obesity who underwent laparoscopic sleeve gastrectomy (LSG) in the hospital from June 2020 to February 2022 were divided into two groups and analyzed retrospectively. The multivariable logistic regression analyses and T test were used to study the influence for operative positions on PONV.Results There were 15 cases of PONV in the prone split-leg position group, with an incidence rate of 50%, and 11 cases of PONV in the supine position group, with an incidence rate of 36.7%(P = 0.297). The operation time in the prone split-leg position group was 168.23 ± 46.24 min and the anesthesia recovery time was 55.03 ± 21.392 min. The operation time in the supine position was 140.60 ± 32.256 min and the anesthesia recovery time was 44.60 ± 13.307 min. There were significant differences between the two groups(P༜0.05). Multivariable analysis showed that the operative positions was not an independent risk factor for PONV, with an OR of 1.192 ( 95%CI: 0.376–3.778, P = 0.766).Conclusions This study showed that the operative positions may affect the PONV. Although, the difference in the incidence of PONV was not significant. The operative positions should be carefully selected for the patients with obesity before surgery.
Financial Public Turbulency After Covid-19 Pandemic Pressure (CPP 19 ) : Study Case in Indonesia
Authors: Basmar Edwin , Salim Zamroni , Widiastuti Tika , Basmar Erlin 
Published: April 2023

Abstract
The Covid-19 pandemic has mutated with various types, we need a model for detect financial turbulence, heavy economic pressures in the form of financial instability and slowing economic growth in Indonesia. The collecting financial data process was obtained during the Covid 19 Pandemic from Bank Indonesia reports 2019 to 2022. Data processing used the Ed Waves Index the development model, which describes the financial cycle wave movement as a reaction form to the Covid-19 pandemic pressures in Indonesia, The study results found that there are three concepts of financial turbulency, first, the Covid-19 Pandemic Pressure (CPP19) which increases, the financial cycle moves negatively by -0.020 Amplitude. Second, the Covid-19 Pandemic Pressure (CPP19) is neutral, the financial cycle moves negatively by -0.009 Amplitude. Third, the decreasing the Covid-19 pandemic pressure (CPP19), the financial cycle moving positively by 0.022 Amplitude, all techniques have an impact on financial stability and economic growth in Indonesia.
JEL Classification: E32, E52, E58
Expression of p53 Combined with Ki-67 in IDH-wildtype Glioblastomas: Prediction by Apparent Diffusion Coefficient Values
Authors: Zhang Bin , Xue Caiqiang , Zhou Qing , Zhang Peng , Han Tao , Deng Liangna , Jing Mengyuan , Zhou Junlin 
Published: April 2023

Abstract
The presence of p53 mutationscombined with high Ki-67 expression can predict poor prognosis and overall survival in IDH-wildtypeglioblastoma patients. This study aims to use magnetic resonance imaging (MRI) features and apparent diffusion coefficient(ADC) values to predict the expression of p53 and Ki-67 in IDH-wildtype glioblastomas to informclinical treatment. We retrospectively collected clinical and imaging data for 103 IDH-wildtype glioblastoma patients in our hospital between June 2021 and February 2023. The datasets were divided into four groups: p53(+)/Ki-67(+), p53(+)/Ki67(-), p53(-)/Ki67(+), and p53(-)/Ki67(-) according to mutant status of p53 and expression level of Ki-67. Six MRI morphological features and four ADC values for the tumor parenchyma were analyzed. In the 103 patients, 21 had p53(-)/Ki-67(-), 12 had p53(+)/Ki-67(-), 28 had p53(-)/Ki-67(+), and 42 had p53(+)/Ki-67(+). Tumor location showed statistically significant differences among the 4 groups (P < 0.05). ADC parameters were negatively correlated with p53 and Ki-67 expression status and could distinguish the co-expression of p53 and Ki-67 (P < 0.05). In distinguishing between the p53(+)/Ki-67(+) and p53(-)/Ki-67(-) groups, when ADCmin was 0.85×10-3 mm2/s, the sensitivity, specificity and accuracy reached their maximum values of 61.90%, 92.90% and 82.54%, respectively. In conclusion, the expression of p53 and Ki-67 in IDH-wildtypeglioblastoma can be evaluated by ADC values. ADC values can be used as a non-invasive quantitative parameter to assist in the clinical diagnosis of IDH-wildtype glioblastoma molecular states.
Venous Blood Gases of Captive Red Foot Tortoise (Chelonoidis carbonarius)
Authors: de Freitas Sofia Silva La Rocca , Garcia Laís Velloso , Santos Jairo Antonio Melo dos , Hirano Líria Queiroz Luz 
Published: April 2023

Abstract
Blood gas analysis evaluates the exchange of oxygen and carbon dioxide in the lungs and provides important information since the state of balance of these gases directly influences the acid-basic balance of the body. Due to the necessity of blood gas parameter measurement for Brazilian reptiles, venous blood gas was determined in captive red foot tortoises. In the present study, 19 animals were used, 8 males and 11 females. Blood was obtained from the dorsal coccygeal vein from the tail, and the analysis was performed immediately after blood collection. The blood parameters pH, PO2, HCO3, TCO2, BEecf, Na, K, ICa, and Glu were compared between females and males, and the values of pH, pCO2, and pO2 were compared with and without temperature correction. A significant difference was observed for the saturation of oxygen and sodium levels between sexes, with higher mean values in males. Furthermore, it was possible to infer that the lower the body temperature in relation to the environment, the greater the pH difference with temperature correction.
Investigating the Role of Proximal Femoral Morphology in Non-Contact ACL Injuries: A Comparative Study
Authors: Musliu Dijon , Bexheti Sadi , Kida Qerim , Kafexholli Ardita , Jashari Redon , Shatri Jeton , Mahmuti Agron , Berisha Lavdim , Karakushi Ardian 
Published: April 2023

Abstract
Purpose: Non-contact ACL injury is a common and debilitating injury among athletes, with high rates of recurrence and long-term consequences. Identifying individuals who are at risk of ACL injury can help prevent or reduce the severity of these injuries. The aim of this study is to assess the role of alpha angle in patients with ACL rupture.
Methodology: This is a case-control study which includes a total of 105 subjects. Hip radiographs were taken in all the subjects using the modified Dunn View radiograph with patient in supine position, hip flexed 45o and abducted 20o. Osirix MD was used to analyse the radiographs and SPSS v.23 for statistical analysis.
Results: The majority of injuries were caused by football (58.1%), followed by jumping sports (23.8%) and skiing (18.1%). A mean difference of 5o of the alpha angle between the groups was measured. Statistical tests showed significant difference between the groups (p<0.001) and logistic regression showing 12-20% risk increase for every degree of alpha angle raise.
Conclusion: The findings showed a substantial correlation between higher alpha angles and an increased likelihood of ACL injury, with patients who ruptured their ACLs having higher mean alpha angles than those who did not. We recommend that young athletes who are actively participating in sports have their hip alpha angles measured so that those with higher alpha angle can follow special prevention programs.
Hypothermia rescued by veno-arterial extracorporeal membrane oxygenation: a case report
Authors: Chen Hao , Yuan Wei , Sun Xiangyou , Sun Yutian , Zhang Jing , Wu Haibo 
Published: April 2023

Abstract
Background: Severe hypothermia is a life-threatening condition that often causes hemodynamic instability or cardiac arrest and carries a high risk of mortality. The use of VA-ECMO in this indication has greatly improved the prognosis of patients.
Case presentation: We describe an incredible case involving the complete recovery of a 47-year-old man placed on VA-ECMO for cardiogenic shock and protracted ventricular fibrillation caused by hypothermia. The patient was discharged home in 20 days with no neurologic sequelae.
Clinical discussion: Extracorporeal life support (ECLS) with cardiopulmonary bypass (CPB) or extracorporeal membrane oxygenation (ECMO) has been recommended as the gold standard for the treatment of severe hypothermia due to its rapid availability and the possibility of prolonged support. Our case demonstrates the effectiveness of ECMO in treating patients with hypothermic cardiogenic shock. At the same time, nutritional support and rehabilitation therapy play an integral role in the whole treatment process. Therefore, it is recommended that such patients be managed by an experienced cardiac team that can evaluate the patient's condition in multiple aspects.
Conclusion: ECMO is effective in the treatment of cardiogenic shock caused by hypothermia.
Income Taxation and Dual Job labour Supply*
Authors: Choe Chung , Oaxaca Ronald , Renna Francesco 
Published: April 2023

Abstract
This paper examines the effects of increasing marginal tax rates on labour supply in a setting in which workers may hold two jobs and may be constrained in their weekly hours on their main jobs. A panel data, multi-equation labour supply model is estimated with correction for tax system endogeneity and multi-sample selection in a correlated random effects framework. Data come from the British Household Panel Survey. The effects of counterfactual increases in marginal tax rates are obtained from Gauss-Seidel simulations of labour supply embedded in a tax system with allowances, tax credits, and child benefits. Labour supply to the main job is reduced by increased marginal tax rates while labour supply to the second job is increased. On net total labour supply is reduced. These effects diminish with increased marginal tax rates. In addition there are labour force withdrawal effects as well as transitions from dual job holding to unitary job holding in response to increased marginal tax rates.
Effect of LiF‑introduced on electrochemical properties of carbon coated silicon suboxide anode material for lithium-ion batteries
Authors: Tang Zhenyuan , Zhang Zhengyu , Wu Jiani , Luo Qian , Lan Lifang , Li Jun 
Published: April 2023

Abstract
Though silicon suboxide (SiOx, 0<x<2) has been considered a new generation of anode material for lithium-ion batteries, the large volume expansion and intrinsic conductivity hinder its commercial applications. In this work, silicon dioxide (SiO2) was prepared via tetraethyl orthosilicate (TEOS) hydrolyzed, and lithium fluoride (LiF) was introduced in situ, and then SiO2/LiF was covered with pyrolyzed sucrose to obtain SiOx/LiF@C. Large elastic modulus, low solubility in a carbonate solution, and high chemical stability LiF was designed to induce the formation of a stable SEI layer on the electrode surface. The more stable interface minimizes the continuous growth of the SEI layer, thereby reducing the resistance and the irreversible decay of capacity. Compared with SiOx@C-3, the SiOx/LiF@C-3 anode displays better electrochemical performance, especially cycle performance at high current density. Benefiting from the cooperation of amorphous carbon coating and stable SEI layer, SiOx/LiF@C-3 activated by low current maintains a specific capacity of 504.2 mAh g-1 and a capacity retention rate of 96% after 300 cycles at a current density of 0.3 A g-1. The great potential of LiF‑introduced for silicon suboxide anode is demonstrated.
Effects of Bone marrow sparing radiotherapy on acute hematologic toxicity for patients with locoregionally advanced cervical cancer: a prospective phase II randomized controlled study
Authors: li wen , Ma Lan , Li Fang , Zhang Yang , Ren Hongtao , Bao Xing , Guo Yuyan , Guo Ya , Li Dan , Ma Xiulong , Wang Zhongwei , Wang Yali , Yin Rutie 
Published: April 2023

Abstract
Background and purpose: To evaluate effects of bone marrow sparing (BMS) radiotherapy on decreasing the incidence of acute hematologic toxicity (HT) for locoregionally advanced cervical cancer (LACC) patients treated by pelvic irradiation.
Materials and methods: LACC patients were recruited prospectively from May 2021 to May 2022 at a single center and were evenly randomized into the BMS group and the control group. All patients received pelvic irradiation with concurrent cisplatin (40 mg/m2 weekly), followed by brachytherapy and BM V40 <25% in the BMS group was additionally prescribed. Acute HT was assessed weekly. Binary logistic regression model and receiver operating characteristic (ROC) curve were used for predictive value analysis. The trial was registered with Chinese clinical trial registry (ChiCTR2200066485).
Results: A total of 242 patients were included in the analysis. Baseline demographic, disease and treatment characteristics were balanced between the 2 groups. In the intention-to-treat population, BMS was associated with a lower incidence of grade ≥2 and grade ≥3 acute HT, leukopenia and neutropenia (72.70% vs 90.90%, P <0.001*; 16.50% vs 65.30%, P <0.001*; 66.10% vs 85.10%, P = 0.001*; 13.20% vs 54.50%, P <0.001*; 37.20% vs 66.10%, P <0.001*; 10.70% vs 43.80%, P <0.001*). BMS also resulted in decreased dose delivered to the organs at risk (OARs) including rectum, bladder and left and right femur head. Univariate and multivariate analyses showed that BM V40 was an independent risk factor for grade ≥3 acute HT (odds ratio [OR] = 2.734, 95% confidence interval [CI] = 1.959-3.815, P <0.001*). Cutoff value was 25.036% and area under the curve (AUC) was 0.786. The nomogram was constructed, which was rigorously evaluated and internally cross-validated, showing good predictive performance.
Conclusions: Receiving BMS pelvic irradiation could reduce the incidence of acute HT in LACC patients, and BM V40 <25% may be a significant factor in reducing the risks of acute HT.
Outcomes for Potentially Resectable Patients Undergoing Primary Chemoradiation Treatment for T1 – T2 HPV Negative Oropharyngeal Squamous Cell Carcinoma
Authors: Laxague Francisco , Fnais Naif , Son Hee Young , Alzahrani Faisal , Mymryk Joe S. , Barrett John W. , Tay Keng Yow , Leung Andrew , Theurer Julie , Nichols Anthony C. , Palma David A. 
Published: April 2023

Abstract
Background
A previous study in HPV-positive patients have shown that transoral surgical resectability (TOS) is a strong prognostic factor for patients with T1-2 disease undergoing radiotherapy (RT), but it is unclear whether this holds for HPV-negative patients, in whom the biology is different and outcomes are worse. We aimed to compare outcomes of potential TOS-candidates vs. non-TOS candidates, among patients who underwent RT/CRT for early T-stage human papillomavirus-negative (HPV-negative) OPSCC.
Methods
For patients treated with RT/CRT for early-stage HPV-negative OPSCC between 2014 and 2021, pretreatment imaging was reviewed by four head-and-neck surgeons, blinded to outcomes, to assess primary-site suitability for TOS, and extracapsular extension (ECE) was assessed by a head-and-neck neuroradiologist. We compared outcomes based on surgical resectability relating to: 1) the primary site tumor alone, and 2) the primary site plus the absence/presence of ECE (overall assessment). Kaplan-Meier curves for overall survival (OS), disease-specific survival (DSS), and progression-free survival (PFS) were compared using the log-rank test, with Cox regression for multivariable modeling.
Results
Seventy patients were included in the analysis. The mean age was 63.1 years and the majority of the patients were male 39/70 (55.7%). The primary site was TOS-favorable in 46/70 (66%). Based on the overall assessment (including the primary site and positive lymph nodes), 41/70 (58.6%) were TOS-favorable. The 3-year OS, DSS and PFS for primary site TOS-favorable vs. unfavorable were OS: 76.9% vs. 37.4%; DSS: 78.1% vs 46.2%, PFS: 69.9% vs 41.3%, (log-rank test = 0.01, 0.03, 0.04; respectively). Additionally, patients with an overall assessment of TOS favorability demonstrated better survival outcomes compared with TOS-unfavorable patients (OS: 77.3% vs. 46.2%; DSS: 78.2% vs. 56.5%, PFS: 72.3% vs. 42.1%, log-rank test = 0.01, 0.04, 0.01; respectively).
Conclusion
Patients with TOS-favorable HPV-negative early T-stage OPSCC have superior survival outcomes than TOS-unfavorable patients. This critical confounder needs to be considered when comparing primary surgical and primary radiation clinical trials and retrospective studies.
Oncolytic adenovirus H101 enhanced antitumor effects of PD-1 blockade by downregulating CD47 on tumor cells
Authors: Qiao Chenxiao , Wang Song , Xu Yipeng , He Yedie , Cai Zhijian , Wang Hua 
Published: April 2023

Abstract
Programmed cell death protein 1/programmed cell death ligand 1 (PD-1/PD-L1) blockade are standard of care for many patients with advanced or metastatic cancer. However, a majority of patients remain resistant to these treatments. It has been reported that local oncolytic viral infection of tumors is capable of overcoming systemic resistance to PD-1 blockade, and strongly suggest the combination therapy of virotherapy with PD-1 blockade to improve therapeutic efficacy in tumors that are refractory to checkpoint blockade. We investigate the antitumor effects of an E1B55KD deleted oncolytic adenovirus H101, in combination with a humanized anti-PD-1 monoclonal antibody Camrelizumab on cancer. Combination of H101 with Camrelizumab demonstrated more potent antitumor effects than monotherapy in immune system humanized NSG mice subcutaneous (S.C.) tumor model. Increased tumor infiltrating T cells including the total and IFN-γ-expressing CD8+ T cells in the combination treatment group were observed. H101 infection induced decreased expression of CD47 on cancer cells, thereby promoting macrophage to phagocytose cancer cells. With the activation of macrophage by H101, increased levels of cytokines including TNF, IL-12 and IFN-γ were observed when induced THP-1 cells were co-cultured with H101-treated cancer cells, which further induced increased expressions of IFN-γ in T cells. Eliminating the IL-12 by anti-IL-12 neutralizing antibodies abolished IFN-γ production from T cells, showing activation of macrophages by H101 induced oncolysis to promote IFN-γ secretion of T cells via IL-12. Meanwhile, infection with H101 induced upregulation of PD-L1 on YTS-1 cells. These results suggested that H101 works synergistically to enhance therapeutic efficacy of PD-1 blockade on cancer by suppressing CD47 signaling, which may promote phagocytose of macrophages to tumor cells and activate CD8+ T cells. Combination of H101 with PD-1 blockade would be a novel strategy for treating cancer.
Li-ion conduction in novel Scandium and Gallium doped Li 1.3 Al 0.29 Ga 0.005 Sc 0.005 Ti 1.7 (PO 4 ) 3 NASICON compound
Authors: Kothari Dharmesh H. , Kanchan D. K. , Kumar Deepak , Chaudhari Ketan 
Published: April 2023

Abstract

Li1.3Al0.3Ti1.7(PO4)3 (LATP) has a high Li+ conductivity of ~ 10− 3 S/cm which can be employed as an inorganic solid electrolyte for solid state batteries. Here we report the electrical properties of gallium and scandium doped forms of LATP viz. Li1.3Al0.3Ti1.7(PO4)3 (LATP), Li1.3Al0.29Ga0.01Ti1.7(PO4)3 (LAGTP) and Li1.3Al0.29Sc0.01Ti1.7(PO4)3 (LASTP) and Li1.3Al0.29Ga0.005 Sc0.005Ti1.7(PO4)3 (LAGSTP). All the samples were prepared by solid state reaction method. Structural characterization was carried out using X-ray diffraction (XRD) and Fourier Transform Infrared (FTIR) techniques whilst electrical properties were studied using Electrochemical Impedance Spectroscopy (EIS). It was found that the larger cations Ga3+ and Sc3+ at octahedral sites change the Ti–O–P bond angle in LTP lattice. This distortion of lattice on ion-ion correlation and subsequently on Li+ ion conduction in the novel LAGSTP material was found to decrease the Li+ ion conductivity to ~ 10− 5 S/cm.
Handy App for Safety Against Violence
Authors: Janokar Sagar , Gaikwad Vijay , Ghuge Siddhant , Ghorpade Sakshi , Gholap Sanveda , Ghuge Pranjal , Ghule Ojasvi 
Published: April 2023

Abstract
Heinous offenses against women have forced us to undertake many precautionary measures and put on a large array of ideas so that to provide security systems to women via their phones. Here we present, an Android Application for women safety, this app can be activated by just normal movements like shaking, as situation demands. Our main agenda is to create a model that removes the financial and physical complexities in GPS, since it is a satellite-based service alongside being available anytime anywhere. GPS system can come handy to extract data which contains parameters like latitude, longitude along with the time details, etc. There exists no prior financial investment for its usage. ’Google Maps’ is a popular service for this purpose. Mobile phone catches hold of location which communicates with the help of General Packet Radio Service (GPRS), being one of the superior modes as far as tracking concerned.