bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using emotion to guide decisions: the accuracy and perceived value of emotional intensity forecasts
Authors: Carlson Steven J. , Levine Linda J. , Lench Heather C. , Flynn Elinor , Winks Kaitlin M. H. , Winckler Britanny E. 
Published: March 2023

AbstractForecasts about future emotion are often inaccurate, so why do people rely on them to make decisions? People may forecast some features of their emotional experience better than others, and they may report relying on forecasts that are more accurate to make decisions. To test this, four studies assessed the features of emotion people reported forecasting to make decisions about their careers, education, politics, and health. In Study 1, graduating medical students reported relying more on forecast emotional intensity than frequency or duration to decide how to rank residency programs as part of the process of being matched with a program. Similarly, participants reported relying more on forecast emotional intensity than frequency or duration to decide which universities to apply to (Study 2), which presidential candidate to vote for (Study 3), and whether to travel as Covid-19 rates declined (Study 4). Studies 1 and 3 also assessed forecasting accuracy. Participants forecast emotional intensity more accurately than frequency or duration. People make better decisions when they can anticipate the future. Thus, people’s reports of relying on forecast emotional intensity to guide life-changing decisions, and the greater accuracy of these forecasts, provide important new evidence of the adaptive value of affective forecasts.
Argumentation as a Speech Act: Two Levels of Analysis
Authors: Haro Marchal Amalia 
Published: March 2023

AbstractFollowing and extending Searle’s speech act theory, both Pragma-Dialectics and the Linguistic Normative Model of Argumentation characterize argumentation as an illocutionary act. In these models, the successful performance of an illocutionary act of arguing depends on the securing of uptake, an illocutionary effect that, according to the Searlean account, characterizes the successful performance of any illocutionary act. However, in my view, there is another kind of illocutionary effect involved in the successful performance of an illocutionary act of arguing, which affects both the speaker’s and the hearer’s set of rights, obligations, and entitlements. In order to give an account of this second type of effect, I will argue that it is necessary to distinguish two levels in the analysis of the illocutionary act of arguing. The first one is related to the illocutionary effect of securing of uptake and thus to the speech act performed by the speaker, while the second one allows us to account for the changes produced by the performance of the illocutionary act of arguing in the deontic modal competence of both the speaker and the hearer.
Chinese Legal Thought on the Global and the Domestic Stage: A Rhetorical Study
Authors: Seppänen Samuli 
Published: March 2023

AbstractChinese Communist Party ideologues and a number of prominent legal scholars have become outspoken about the global significance of Chinese legal thought. The question is, however, whether the ambitious statements about the global importance of Chinese legal thought are supported by legal theoretical arguments, which could be influential abroad. This article examines the interaction between the domestic and global stages of Chinese legal speech through the tools of rhetorical theory. Arguments about the nature and global significance of Chinese law are made for different purposes and for different audiences. The most ambitious statements about the global significance of Chinese legal thought are produced within a ‘ceremonial’ genre of speech. Domestic Chinese ceremonial speech is meaningful in the Chinese context, but it translates poorly to globally influential ideological speech. Foreign audiences will find more persuasive arguments about the significance of Chinese legal thought in Chinese deliberative speech, such as parts of Chinese legal scholarship. While arguments made in the deliberative genre are more persuasive than ceremonial speech, specific argumentative moves within this genre are not always helpful for the international advocacy of Chinese legal thought. Moreover, arguments in the deliberative genre are not consistently reflected in Chinese judicial decisions. These observations highlight the role of language and persuasion in the globalisation of law.
Not an “Ordinary Man”: J. Gresham Machen and the Un-Queering of Evangelical Theology
Authors: Steelman Austin 
Published: March 2023

ABSTRACTIn the 1920s, Princeton Seminary professor J. Gresham Machen was the leading fundamentalist intellectual of the Fundamentalist-Modernist controversy. His Calvinist theology, commitment to biblical inerrancy, and opposition to liberalism were passed on to and spread by his influential students including Carl McIntire, Harold Ockenga, and Francis Schaeffer. But in the early days of 1906, the young man who would go on to indelibly shape evangelical theology wrote home from Germany where he was a graduate student that he could never go into Christian ministry because of his “moral fault” that no “ordinary man” could understand. This article analyzes the coded language of J. Gresham Machen's letters during his pivotal personal crisis in the context of changing German understandings of “homosexuality” and Machen's lifelong homosocial tendencies. Moreover, it connects Machen's confrontation with his sexuality with his simultaneous confrontation with German liberal theology. In the fall of 1905, Machen found himself drawn to the more experiential and pluralistic Christianity of Wilhelm Herrmann. However, in facing his own perceived immorality, Machen found “Calvinism a very comforting doctrine indeed.” He rejected modernism and spent his life defending a rigid orthodoxy against the theologies that would come to accommodate and embrace queerness. The results of his personal crisis echoed through the history of twentieth-century American evangelicalism. This article analyzes the historical process of “un-queering” theology that emanated from that crisis and demonstrates that resistance to queerness was woven into the ideological fabric of evangelicalism far earlier than scholars have yet recognized.
Kefir as a therapeutic agent in clinical research: a scoping review
Authors: Bessa Milena Klippel , Bessa Giancarlo Rezende , Bonamigo Renan Rangel 
Published: March 2023

AbstractIncreasing research has been conducted on the role of probiotics in disease treatment. Kefir, a safe, low-cost probiotic fermented milk drink, has been investigated in manyin vitroand animal studies, although parameters for human therapeutic dose or treatment time have not yet been determined. Here we perform a scoping review of clinical studies that have used kefir as a therapeutic agent, compiling the results for perspectives to support and direct further research. This review was based on Joanna Briggs Institute guidelines, including studies on the effects of kefir-fermented milk in humans. Using the term KEFIR, the main international databases were searched for studies published in English, Spanish or Portuguese until 9 March 2022. A total of 5835 articles were identified in the four databases, with forty-four eligible for analysis. The research areas were classified as metabolic syndrome and type 2 diabetes, gastrointestinal health/disorders, maternal/child health and paediatrics, dentistry, oncology, women’s and geriatric health, and dermatology. The many study limitations hampered generalisation of the results. The small sample sizes, methodological variation and differences in kefir types, dosage and treatment duration prevented clear conclusions about its benefits for specific diseases. We suggest using a standard therapeutic dose of traditionally prepared kefir in millilitres according to body weight, making routine consumption more feasible. The studies showed that kefir is safe for people without serious illnesses.
A novel approach toward the generation of oocytes by direct diploid cell haploidization
Authors: Setton Robert , Xie Philip , Rosenwaks Zev , Palermo Gianpiero D. 
Published: March 2023

SummaryOocyte-mediated somatic cell haploidization is a process in which a diploid cell halves its chromosomal content by segregating its homologue within the ooplasm. Replacing the donor oocyte nucleus with a patient’s female diploid somatic nucleus can generate patient-genotyped oocytes. Insemination of these resulting constructs enables their activation and induces a reductive meiotic division, haploidizing the diploid female donor cell that can subsequently support syngamy with the male genome and create a zygote. So far, experimental data for this method have been limited and have not consistently proven the generation of chromosomally normal embryos. Overall, we achieved reconstruction of murine oocytes with a micromanipulation survival rate of 56.5%, and a correct haploidization and fertilization rate of 31.2%, resulting in a 12.7% blastocyst rate. Time-lapse analysis revealed that reconstructed embryos underwent a timely polar body extrusion and pronuclear appearance followed by a satisfactory embryonic cleavage, comparable with the control. Whole genome sequencing of the analyzed embryos indicated that 27.3% (6/22) were properly diploid. Our findings suggest that diploid cell haploidization may be a feasible technique for creating functional gametes in mammals.
A pilot randomized study of a telephone-based cognitive-behavioral stress-management intervention to reduce distress in phase 1 oncology trial caregivers
Authors: Carr Alaina L. , Bilenduke Emily , Adolf Esmeralda , Kessler Elizabeth R. , Arch Joanna J. , Ranby Krista W. , Kilbourn Kristin 
Published: March 2023

AbstractObjectivesCaregivers of adult phase 1 oncology trial patients experience high levels of distress and face barriers to in-person supportive care. The Phase 1 Caregiver LifeLine (P1CaLL) pilot study assessed the feasibility, acceptability, and general impact of an individual telephone-based cognitive behavioral stress-management (CBSM) intervention for caregivers of phase I oncology trial patients.MethodsThe pilot study involved 4 weekly adapted CBSM sessions followed by participant randomization to 4 weekly cognitive behavioral therapy sessions or metta-meditation sessions. A mixed-methods design used quantitative data from 23 caregivers and qualitative data from 5 caregivers to examine the feasibility and acceptability outcomes. Feasibility was determined using recruitment, retention, and assessment completion rates. Acceptability was assessed with self-reported satisfaction with program content and participation barriers. Baseline to post-intervention changes in caregiver distress and other psychosocial outcomes were assessed for the 8-session intervention.ResultsThe enrollment rate was 45.3%, which demonstrated limited feasibility based on an a priori criterion enrollment rate of 50%. Participants completed an average of 4.9 sessions, with 9/25 (36%) completing all sessions and an 84% assessment completion rate. Intervention acceptability was high, and participants found the sessions helpful in managing stress related to the phase 1 oncology trial patient experience. Participants showed reductions in worry and isolation and stress.Significance of resultsThe P1CaLL study demonstrated adequate acceptability and limited feasibility and provided data on the general impact of the intervention on caregiver distress and other psychosocial outcomes. Caregivers of phase 1 oncology trial patients would benefit from supportive care services; a telephone-based intervention may have more utilization and thus make a larger impact.
Political determinants of health: (re) examining the role of governance in reducing maternal mortality
Authors: Tiwari Chhavi , Jain Neha , Goli Srinivas , Puri Parul 
Published: March 2023

AbstractGiven change in the universal developmental agenda and the quality of governance in the last two decades, this paper re-examines the relationship between governance, health expenditure and maternal mortality using panel data for 184 countries from 1996 to 2019. By employing the ‘dynamic panel data regression model’, the study reveals that a one-point improvement in the governance index decreases maternal mortality by 10–21%. We also find that good governance can better translate health expenditure into improved maternal health outcomes through effective allocation and equitable distribution of available resources. These results are robust to alternative instruments, alternative dependent variables (such as infant mortality rate and life expectancy), estimation by different governance dimensions and at the sub-national level. Additional findings using ‘Quantile regression’ estimates show that the quality of governance matters more than the health expenditure in countries with a higher level of maternal mortality. While the ‘Path regression’ analysis exhibits the specific direct and indirect mechanisms through which the causal inference operates between governance and maternal mortality.
On the Systematic Occurrence of Compound Cold Spells in North America and Wet or Windy Extremes in Europe
Authors: Messori Gabriele , Faranda Davide 
Published: March 2023

AbstractThe repeated co‐occurrence of cold spells over Eastern North America and wet or windy extremes over Western Continental Europe during recent winters, has led to hypothesize a link between the two. Here, we analyze the interplay between the large‐scale atmospheric circulation and co‐occurring cold spells in North America and wet or windy extremes in Europe. We collectively term these occurrences compound cold–wet–windy extremes. We leverage a recent approach grounded in dynamical systems theory, which provides an analytically and computationally efficient analysis of spatially resolved, multivariate climate extremes. We find that there are specific, recurrent large‐scale atmospheric circulation patterns systematically associated with both the individual extremes and co‐occurring cold–wet–windy anomalies. Evidence for this is also found when focusing on compound cold–wet–windy extremes, although with a weaker signal. This motivates further analyses focusing specifically on the statistics and drivers of these compound extreme occurrences.
Pore‐Scale Observations of Hydrogen Trapping and Migration in Porous Rock: Demonstrating the Effect of Ostwald Ripening
Authors: Zhang Yihuai , Bijeljic Branko , Gao Ying , Goodarzi Sepideh , Foroughi Sajjad , Blunt Martin J. 
Published: March 2023

AbstractWe use high‐resolution three‐dimensional X‐ray imaging to study hydrogen injection and withdrawal in the pore space of Bentheimer sandstone. The results are compared with a replicate experiment using nitrogen. We observe less trapping with hydrogen because the initial saturation after drainage is lower due to channeling. Remarkably we observe that after imbibition, if the sample is imaged again after 12 hr, there is a significant rearrangement of the trapped hydrogen. Many smaller ganglia disappear while the larger ganglia swell, with no detectable change in overall gas volume. For nitrogen, the fluid configuration is largely unchanged. This rearrangement is facilitated by concentration gradients of dissolved gas in the aqueous phase—Ostwald ripening, We estimate the time‐scales for this effect to be significant, consistent with the experimental observations. The swelling of larger ganglia potentially increases the gas connectivity, leading to less hysteresis and more efficient withdrawal.
Conditions for Inception of Relativistic Runaway Discharges in Air
Authors: Pasko Victor P. , Celestin Sebastien , Bourdon Anne , Janalizadeh Reza , Jansky Jaroslav 
Published: March 2023

AbstractTerrestrial gamma‐ray flashes are linked to growth of long bidirectional lightning leader system consisting of positive and stepping negative leaders. The spatial extent of streamer zones of a typical lightning leader with tip potential exceeding several tens of megavolts is on the order of 10–100 m. The photoelectric absorption of bremsstrahlung radiation generated by avalanching relativistic runaway electrons occurs efficiently on the same spatial scales. The intense multiplication of these electrons is triggered when the size of the negative leader streamer zone crosses a threshold of approximately 100 m (for sea‐level air pressure conditions) allowing self‐replication of these avalanches due to the upstream relativistic electron seeds generated by the photoelectric absorption. The model results also highlight importance of electrode effects in interpretation of X‐ray emissions from centimeter to meter long laboratory discharges, in particular, a similar feedback effect produced by generation of runaway electrons from the cathode material.
Long‐Lead Drought Forecasting Across the Continental United States Using Burg Entropy Spectral Analysis With a Multiresolution Approach
Authors: Han Jeongwoo , Singh Vijay P. 
Published: March 2023

AbstractAmid climate change, extreme droughts have occurred more frequently, accompanied by increasing socio‐economic‐environmental losses. To be prepared for upcoming droughts, proactive drought management planning based on drought forecasting is being highlighted. This study, therefore, developed a long‐term drought forecasting model using Burg entropy spectral analysis with the maximal overlap discrete wavelet transform across the continental United States (CONUS). The model forecasted monthly self‐calibrated Palmer Drought Severity Index (scPDSI) up to median lead times of 12 months with root mean square error less than 0.8 and the modified Nash‐Sutcliffe efficiency coefficient greater than 0.6 across CONUS. The lead‐time with an acceptable accuracy was affected by how the model parameterized low‐frequency structure of scPDSI that was significantly correlated to sea surface temperature climate mode. The correlation between low‐frequency signals and Niño‐3.4 tended to be weaker for the regions located at higher elevations. Thus, higher variability in spectral structures of low‐frequency signals at higher elevation‐regions led to shorter memory/persistency of time series that shortened the forecast lead time. Besides, higher variability in precipitation linked to the variability of scPDIS also shortened the forecast lead time. To appraise the applicability of the suggested forecast model to drought management planning, drought characteristics (i.e., severity, duration, and area) were obtained by the three‐dimensional drought clustering algorithm for the forecasted and observed scPDSI. Then, risk was analyzed for drought characteristics using the vine copula. Risk analysis for drought characteristics forecasted up to a 12‐month lead time showed the potential for applicability of the model to drought mitigation plans.
Reducing default mode network connectivity with mindfulness-based fMRI neurofeedback: a pilot study among adolescents with affective disorder history
Authors: Zhang Jiahe , Raya Jovicarole , Morfini Francesca , Urban Zoi , Pagliaccio David , Yendiki Anastasia , Auerbach Randy P. , Bauer Clemens C. C. , Whitfield-Gabrieli Susan 
Published: March 2023

AbstractAdolescents experience alarmingly high rates of major depressive disorder (MDD), however, gold-standard treatments are only effective for ~50% of youth. Accordingly, there is a critical need to develop novel interventions, particularly ones that target neural mechanisms believed to potentiate depressive symptoms. Directly addressing this gap, we developed mindfulness-based fMRI neurofeedback (mbNF) for adolescents that aims to reduce default mode network (DMN) hyperconnectivity, which has been implicated in the onset and maintenance of MDD. In this proof-of-concept study, adolescents (n = 9) with a lifetime history of depression and/or anxiety were administered clinical interviews and self-report questionnaires, and each participant’s DMN and central executive network (CEN) were personalized using a resting state fMRI localizer. After the localizer scan, adolescents completed a brief mindfulness training followed by a mbNF session in the scanner wherein they were instructed to volitionally reduce DMN relative to CEN activation by practicing mindfulness meditation. Several promising findings emerged. First, mbNF successfully engaged the target brain state during neurofeedback; participants spent more time in the target state with DMN activation lower than CEN activation. Second, in each of the nine adolescents, mbNF led to significantly reduced within-DMN connectivity, which correlated with post-mbNF increases in state mindfulness. Last, a reduction of within-DMN connectivity mediated the association between better mbNF performance and increased state mindfulness. These findings demonstrate that personalized mbNF can effectively and non-invasively modulate the intrinsic networks associated with the emergence and persistence of depressive symptoms during adolescence.
Pathways to the persistence of drug use despite its adverse consequences
Authors: McNally Gavan P. , Jean-Richard-dit-Bressel Philip , Millan E. Zayra , Lawrence Andrew J. 
Published: March 2023

AbstractThe persistence of drug taking despite its adverse consequences plays a central role in the presentation, diagnosis, and impacts of addiction. Eventual recognition and appraisal of these adverse consequences is central to decisions to reduce or cease use. However, the most appropriate ways of conceptualizing persistence in the face of adverse consequences remain unclear. Here we review evidence that there are at least three pathways to persistent use despite the negative consequences of that use. A cognitive pathway for recognition of adverse consequences, a motivational pathway for valuation of these consequences, and a behavioral pathway for responding to these adverse consequences. These pathways are dynamic, not linear, with multiple possible trajectories between them, and each is sufficient to produce persistence. We describe these pathways, their characteristics, brain cellular and circuit substrates, and we highlight their relevance to different pathways to self- and treatment-guided behavior change.
Intrinsic neural timescales in autism spectrum disorder and schizophrenia. A replication and direct comparison study
Authors: Uscătescu Lavinia Carmen , Kronbichler Martin , Said-Yürekli Sarah , Kronbichler Lisa , Calhoun Vince , Corbera Silvia , Bell Morris , Pelphrey Kevin , Pearlson Godfrey , Assaf Michal 
Published: March 2023

AbstractIntrinsic neural timescales (INT) reflect the duration for which brain areas store information. A posterior–anterior hierarchy of increasingly longer INT has been revealed in both typically developed individuals (TD), as well as persons diagnosed with autism spectrum disorder (ASD) and schizophrenia (SZ), though INT are, overall, shorter in both patient groups. In the present study, we aimed to replicate previously reported group differences by comparing INT of TD to ASD and SZ. We partially replicated the previously reported result, showing reduced INT in the left lateral occipital gyrus and the right post-central gyrus in SZ compared to TD. We also directly compared the INT of the two patient groups and found that these same two areas show significantly reduced INT in SZ compared to ASD. Previously reported correlations between INT and symptom severity were not replicated in the current project. Our findings serve to circumscribe the brain areas that can potentially play a determinant role in observed sensory peculiarities in ASD and SZ.