bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anophelessalivary apyrase regulates blood meal hemostasis and drives malaria parasite transmission
Authors: Pala Zarna Rajeshkumar , Alves e Silva Thiago Luiz , Minai Mahnaz , Crews Benjamin , Patino-Martinez Eduardo , Carmona-Rivera Carmelo , Valenzuela-Leon Paola Carolina , Martin-Martin Ines , Flores-Garcia Yevel , Cachau Raul E. , Srivastava Naman , Moore Ian N. , Alves Derron A. , Kaplan Mariana J , Fischer Elizabeth , Calvo Eric , Vega-Rodriguez Joel 
Published: May 2023

AbstractMosquito salivary proteins play a crucial role in regulating hemostatic responses at the bite site during blood feeding. In this study, we investigate the function ofAnopheles gambiaesalivary apyrase (AgApyrase) inPlasmodiumtransmission. Our results demonstrate that salivary apyrase interacts with and activates tissue plasminogen activator, facilitating the conversion of plasminogen to plasmin, a human protein previously shown to be required forPlasmodiumtransmission. Microscopy imaging shows that mosquitoes ingest a substantial amount of apyrase during blood feeding which reduces coagulation in the blood meal by enhancing fibrin degradation and inhibiting platelet aggregation. Supplementation ofPlasmodiuminfected blood with apyrase significantly enhancedPlasmodiuminfection in the mosquito midgut. In contrast, AgApyrase immunization inhibitedPlasmodiummosquito infection and sporozoite transmission. This study highlights a pivotal role for mosquito salivary apyrase for regulation of hemostasis in the mosquito blood meal and forPlasmodiumtransmission to mosquitoes and to the mammal host, underscoring the potential for new strategies to prevent malaria transmission.
ROP GTPase regulates polarised cell growth and cell division orientation during tissue development and organogenesis inMarchantia polymorpha
Authors: Mulvey Hugh , Dolan Liam 
Published: May 2023

SUMMARYCell polarity – broadly defined as the asymmetric distribution of cellular activities and or subcellular components within a cell – determines the geometry of cell growth and division during development. RHO GTPase proteins regulate the establishment of cell polarity and are conserved among eukaryotes. RHO Of Plant (ROP) proteins are a subgroup of RHO GTPases that are required for cellular morphogenesis in plants. However, how ROP proteins modulate the geometry of cell growth and division during the morphogenesis of plant tissues and organs is not well understood. To investigate how ROP proteins function during tissue development and organogenesis, we characterised the function of the single copyROPgene of the liverwortMarchantia polymorpha.M. polymorphadevelops morphologically complex three-dimensional tissues and organs exemplified by air chambers and gemmae, respectively. Mproploss of function mutants form defective air chambers and gemmae, indicating ROP function is required for tissue development and organogenesis. During air chamber and gemma development in wild-type, the MpROP protein is enriched to sites of polarised growth at the cell surface and accumulates at the expanding cell plate of dividing cells. Consistent with these observations, polarised cell growth is lost, and cell divisions are misoriented in Mpropmutants. We propose that ROP regulates both polarised cell growth and cell division orientation in a coordinated manner to orchestrate tissue development and organogenesis in land plants.
A redox switch allows binding of Fe(II) and Fe(III) ions in the cyanobacterial iron binding protein FutA fromProchlorococcus
Authors: Bolton Rachel , Machelett Moritz M. , Stubbs Jack , Axford Danny , Caramello Nicolas , Catapano Lucrezia , Malý Martin , Rodrigues Matthew J. , Cordery Charlotte , Tizzard Graham J. , MacMillan Fraser , Engilberge Sylvain , von Stetten David , Tosha Takehiko , Sugimoto Hiroshi , Worrall Jonathan A.R. , Webb Jeremy S. , Zubkov Mike , Coles Simon , Mathieu Eric , Steiner Roberto A. , Murshudov Garib , Schrader Tobias E. , Orville Allen M. , Royant Antoine , Evans Gwyndaf , Hough Michael A. , Owen Robin L. , Tews Ivo 
Published: May 2023

AbstractThe marine cyanobacteriumProchlorococcusis a main contributor to global photosynthesis, whilst being limited by iron availability. Cyanobacterial genomes typically encode two different types of FutA iron binding proteins: periplasmic FutA2 ABC transporter subunits bind Fe(III), while cytosolic FutA1 binds Fe(II). Owing to their small size and their economized genomeProchlorococcusecotypes typically possess a singlefutAgene. How the encoded FutA protein might bind different Fe oxidation states was previously unknown. Here we use structural biology techniques at room temperature to probe the dynamic behavior of FutA. Neutron diffraction confirmed four negatively charged tyrosinates, that together with a neutral water molecule coordinate iron in trigonal bipyramidal geometry. Positioning of the positively charged Arg103 side chain in the second coordination shell yields an overall charge-neutral Fe(III) binding state in structures determined by neutron diffraction and serial femtosecond crystallography. Conventional rotation X-ray crystallography using a home source revealed X-ray induced photoreduction of the iron center with observation of the Fe(II) binding state; here, an additional positioning of the Arg203 side chain in the second coordination shell maintained an overall charge neutral Fe(II) binding site. Dose series using serial synchrotron crystallography and an XFEL X-ray pump-probe approach capture the transition between Fe(III) and Fe(II) states, revealing how Arg203 operates as a switch to accommodate the different iron oxidation states. This switching ability of theProchlorococcusFutA protein may reflect ecological adaptation by genome streamlining and loss of specialized FutA proteins.Significance StatementOceanic primary production by marine cyanobacteria is a main contributor to carbon and nitrogen fixation.Prochlorococcusis the most abundant photosynthetic organism on Earth, with an annual carbon fixation comparable to the net global primary production from agriculture. Its remarkable ecological success is based on the ability to thrive in low nutrient waters. To manage iron limitation,Prochlorococcuspossesses the FutA protein for iron uptake and homeostasis. We reveal a molecular switch in the FutA protein that allows it to accommodate binding of iron in either the Fe(III) or Fe(II) state using structural biology techniques at room temperature and provide a plausible mechanism for iron binding promiscuity.
Between street and digital capital? A qualitative study of judicial sentencing of persons convicted of online drug dealing in Sweden
Authors: Nordgren Johan , Tiberg Fredrik 
Published: May 2023

Purpose
Drug sales facilitated through digital communication on the surface web and on darknet cryptomarkets have increased during the past two decades. This has resulted in an increase in drug law enforcement efforts to combat these markets and a subsequent increase in judicial sentencing of people selling drugs online. The aim of this study was to analyze how Swedish courts describe sentenced sellers and how the courts apply case law.

Design/methodology/approach
The empirical material consists of 71 sentencing documents produced by Swedish courts in cases of online drug selling between January 1, 2010 and January 1, 2020. In total, 99 sentenced persons occur in the documents. Using a qualitative research design, the authors analyzed the material through thematic text analysis.

Findings
Overall, in their descriptions of online drug sale operations, the courts’ characterizations of the concepts of street capital and digital capital show a dichotomy. These forms of capital are situationally described as both aggravating and mitigating aspects in the application of case law, indicating that it may be fruitful to view both street and digital capital as resources used on contemporary drug markets in general.

Originality/value
Very little research exists into how judicial systems describe and perceive the developing phenomenon of online drug sales. Using a relatively large sample from a decade of sentencing, the authors provide an analysis of how Swedish courts view and valuate capital forms in the online drugs trade.
Person-organization fit, person-job fit and organizational commitment among hotel employees: the roles of positive affect and calling
Authors: Park In-Jo , Hai Shenyang 
Published: May 2023

Purpose
Drawing on affective events theory, the purpose of this study is to examine the mediation effect of positive affect on the association between fit (e.g. person-organization fit and person-job fit) and organizational commitment in the hospitality industry. The secondary aim is to investigate the moderated mediation effect of hospitality employees’ calling on these associations.

Design/methodology/approach
The authors collected data from 248 hotel employees in China at three different time points. A moderated mediation model was examined by using the bias-corrected bootstrapping method.

Findings
Results revealed that person-organization fit and person-job fit indirectly influenced organizational commitment via positive affect. Calling was found to moderate the indirect influences of person-organization and person-job fit on organizational commitment via positive affect.

Practical implications
Managing employees’ affective experiences in the hospitality industry and promoting their organizational commitment are key strategies for hospitality organizations to promote service quality and retain their employees. This study suggests that hospitality organizations should actively attempt to improve employees’ fit perceptions and promote their sense of calling.

Originality/value
By theorizing and investigating the mediating role of positive affect and the moderating role of calling in the association between fit and employee commitment, this research extends existing knowledge on the association between fit–job attitudes and makes notable contributions to the hospitality literature on fit, affect, calling and job attitudes.
Employee and customer perspectives in discovering the antecedent and output relationships for hotel branding development
Authors: Liu Chih-Hsing 
Published: May 2023

Purpose
The purpose of this study is to propose and develop an antecedent model from star hotel employee viewpoint and a consequence model for star hotel customers’ evaluation of the brand equity development process.

Design/methodology/approach
In terms of the study setting, structural equation modelling was conducted. Study 1 used the views of 323 star hotels’ employees on the mutual relationships among employee-based brand equity, and Study 2 used 516 star hotels’ customer perspectives concerning the mutual relationships among customer-based brand equity.

Findings
In the antecedent model of Study 1 from an employee viewpoint, service quality is a foundational attribute of the indirect influences of brand equity development through brand promise, values and message. A moderating role of brand identity is also found. In the consequence model of Study 2 from the perspective of customers’ evaluation, mutual relationships of brand equity are identified, and social interactions are established that enhance the positive relationships among the different critical attributes of brand equity.

Originality/value
Although numerous hotel branding studies have identified the consequences of hotels for employees, few have simultaneously considered employees and customer feedback in terms of star hotel branding. This research considers the bidirectional effects of such a comprehensive perspective.
Using theory of mind to understand the impact of Covid-19 fear on healthcare workers’ withdrawal intentions
Authors: Saini Garima , Dash Sanket Sunand , Tiwari Anurag 
Published: May 2023

PurposeHealthcare workers’ (HCWs’) job-related high exposure to Covid-19 virus arouses fear of Covid-19 among them. Based on the Theory of Mind (ToM), the study predicts that fears will lead to negative psychological (psychological distress) and behavioral (withdrawal intentions) outcomes. ToM is also used to identify social intelligence as a means to counter fear of Covid-19 on heightened psychological distress and increased withdrawal intentions.Design/methodology/approachTo investigate the study design, a sample of 262 HCWs, including doctors, nurses and technicians, were surveyed using standardized questionnaires.FindingsAs predicted, Covid-19 fear led to increased withdrawal intentions with heightened psychological distress partially mediating the relationship. The alleviating role of social intelligence on the effects of Covid-19 was supported as high social intelligence reduced HCWs’ turnover intentions, with decreased psychological distress partially mediating the relationship.Originality/valueGiven the universality of the Theory of Mind (ToM), the findings of this study are likely to be generalizable to all pandemics. The study results support the increased application of ToM in organizational settings and have both theoretical and practical implications for health administrators. Based on study results, health administrators are exhorted to develop ToM-based mental models to understand and deal with the fear of contagious diseases. Health administrators can also increase HCWs’ social intelligence to deal with the negative perceptual and behavioral outcomes arising from the emotions aroused by the nature of their work.
Do globalised economies benefit more from export sophistication? Evidence from advanced and developing economies
Authors: Haini Hazwan , Pang Wei Loon 
Published: May 2023

PurposeThis study examines whether the gains from export sophistication is conditional on the level of globalisation. Previous studies have shown that the impact of export sophistication on growth varies depending on the level of a country's economic development. The authors argue that globalisation plays an important role in influencing the gains from export sophistication, mainly through the competition and scale effects. The competition effect disincentivises domestic firms to engage in export markets, while the scale effect incentivises knowledge accumulation and innovation.Design/methodology/approachThe authors employ data from 163 economies from 1995 to 2018. The authors re-estimate values for export sophistication using ordinary goods from 1995 to 2018 and estimate a growth model using the generalised method of moments (GMM) to control for endogeneity and simultaneity issues.FindingsThe results show that the gains from export sophistication and globalisation is greater for economies with higher levels of economic development compared to economies with low levels of economic development. Moreover, the authors find that the gains from export sophistication are conditional on the level of globalisation. The authors’ results show that the marginal impact of export sophistication diminishes as developing economies become more globalised, while advanced economies gain more from export sophistication when globalisation precedes at a higher level.Originality/valuePrevious studies have generally examined the conditional growth effects of export sophistication on trade, economic development and other structural factors. To the best of the authors’ knowledge, this is the first study to examine the impact of globalisation, and the authors exploit the multidimensional concept of globalisation to test the hypothesis.Peer reviewThe peer review history for this article is available at: https://publons.com/publon/10.1108/IJSE-01-2023-0001.
Antecedents of team alignment for team performance: length of relationship as a moderator
Authors: Jadhav Dhananjay , Fatima Johra Kayeser , Quazi Ali 
Published: May 2023

Purpose
While scholarly attention has mainly focused on team-level or relational constructs for the success of team performance, understanding the inter-play between these two streams of research remains limited in digital transformation projects. Borrowing from social exchange theory, this study aims to explore the antecedents of team alignment leading to team performance with mediation effects of trust, commitment and customer–service provider relationship. The moderating role of relationship length was also examined.

Design/methodology/approach
Data was collected using a survey of 180 employees working on digital projects in B2B context, mostly in the Indo-Pacific region, specifically Singapore, Indonesia, Malaysia and India. Partial least squares method with multi-group analyses and bootstrapping method were used to analyze the data.

Findings
Findings show that customer control and team capability are the strongest antecedents of team alignment, and inter-play between the customer–provider relationship with team-level constructs is also significant. Relationship length has higher level of moderation impact on trust–team performance link compared to commitment–team performance relationship.

Research limitations/implications
The study considers moderation impact of relationship length on trust, commitment and team performance but not other constructs. Also, gender ratio is skewed in the data set.

Practical implications
Digital transformation practitioners need to be aware of relational constructs (not only team-level constructs) when designing successful long-term digitalization strategies for organizations.

Originality/value
This study is one of the first to document the inter-play between team alignment and relational constructs (such as trust, commitment, and customer–service provider relationship), with moderation impact of relationship length leading to team performance in digital transformation projects.
A study of workplace bullying and coping strategies in hospitality sector: role of moral injury and inclusive leadership
Authors: Srivastava Shalini , Khan Muskan , Kumari Arpana , Jain Ajay Kumar 
Published: May 2023

PurposeBased on the stimulus-organism-response (SOR) model and Transactional Model of Stress and Coping, the current study aims to investigate the direct effects of workplace bullying (WPB) on internal whistleblowing (IW) and workplace withdrawal (WW), as well as the indirect effects, including the mediating role of moral injury (MI) and moderating role of inclusive leadership (IL) in the hospitality sector.Design/methodology/approachThree-waves approach was used to collect data from 266 hotel employees in India. AMOS 21 and Macro-PROCESS were used to analyse the hypothesised relationships.FindingsWPB has a direct effect on IW and workplace withdrawal. MI mediated the relationship between WPB and IW and WPB and WW. Further, IL moderated the relationship between WPB and MI.Practical implicationsThe results of the current study have significant policy-related, academic and practical implications. Executives must be aware of WPB incidents and take prompt action to completely stop them.Originality/valueThe study contributes to the literature by analysing the role of MI as a mediator for the relationship between WPB and WPB's coping strategies like IW and workplace withdrawal. This study also answers repeated calls for more research on MI and MI's consequences.
Exploring the influence of risk management on the performance of industry–university collaborative projects: the moderating role of knowledge management capabilities
Authors: Daradkeh Mohammad 
Published: May 2023

PurposeEffective management of risk and knowledge is critical to ensure the success of industry–university collaboration (IUC) projects. However, the intricate dynamics through which these factors influence the performance of IUC projects have yet to be fully investigated. The purpose of this study is to explore the interplay between risk management and knowledge management capabilities and their impact on IUC project performance.Design/methodology/approachA model was constructed and evaluated through the examination of a sample of 188 collaborative innovation projects located in the United Arab Emirates (UAE), utilizing structural equation models (SEM) and hierarchical regression analysis.FindingsThe findings indicate that social system risk, technical system risk and project management risk have a negative impact on the performance of university–industry collaboration (UIC) projects, while cultural, technical and structural knowledge management capabilities can mitigate the negative impact of these risks on the performance of IUC projects.Practical implicationsThe study concludes with three recommendations aimed at improving the management of UIC projects, including the establishment of a distinct and precise management strategy, the deployment of a comprehensive and systematized management methodology and the adoption of a balanced management framework.Originality/valueThe originality and value of this study lie in its exploration of the interplay between risk management and knowledge management capabilities in IUC projects. While previous studies have examined either risk management or knowledge management in IUC projects separately, this study provides a comprehensive analysis of both factors and their combined impact on project performance. The study also contributes to the literature by highlighting the specific risks and knowledge management capabilities that are most relevant to the context of IUC projects in the UAE. The practical recommendations offered by the study can help project managers and stakeholders to improve the success of collaborative innovation projects.
Bridging the power gap: the impact of pedagogical strategies and relationship-building on student success
Authors: Marmet Matthew D. 
Published: May 2023

PurposeThis study was designed to assess the efficacy of pedagogical and relationship-building strategies employed to foster student engagement and success. Also, it was meant to demonstrate the importance of faculty to engagement and success, and emphasize a faculty member's role in lessening the power divide that can exist in classrooms.Design/methodology/approachFirst, archival survey data were explored that provide a baseline for student perceptions of the interactions with faculty that have been shown to impact student engagement. Second, an in-depth description of the course taught by this author is provided, along with the relationship-building and pedagogical strategies employed to promote student engagement and learning. Finally, a mixed-methods approach was utilized to capture whether improved engagement and learning occurred. Both qualitative data, in the form of student opinionnaires, and quantitative data gathered from the institution's assessment instrument were reviewed.FindingsA review of the qualitative survey data found that students believe faculty should be very intentional about building relationships with them. Student opinionnaires confirmed the efficacy of the relationship-building tactics employed by the instructor. Additionally, data analysis of the learning assessment tool yielded an 18% increase in performance, lending further support to the classroom strategies utilized during this time.Originality/valueThe results of this study add to the body of literature addressing the impact faculty have on student engagement. Additionally, these results can be used to help inform institutional strategies, such as faculty development seminars, to improve retention as a result of an engaged student body.