bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hazard consistent record selection procedures accounting for horizontal and vertical components of the ground motion: Application to liquid storage tanks
Authors: Kohrangi Mohsen , Bakalis Konstantinos , Triantafyllou Georgios , Vamvatsikos Dimitrios , Bazzurro Paolo 
Published: January 2023

AbstractA methodology is proposed to enable state‐of‐the‐art record selection using ground motion components in all three principal loading directions. Relying on the well‐established Conditional Spectrum approach, its fundamental concepts are extended to ensure hazard consistency when the vertical ground motion component is considered along with the horizontal ones. To this end, different record selection techniques are employed, spanning sets of ground motion records with and without vertical motions, as well as with and without vertical ground motion hazard consistency. To demonstrate the effect that each record set can potentially have on a structure, an unanchored liquid storage tank is adopted as a case study, because of the vertical uplift motion it can exhibit, even under the application of horizontal loading only. A reduced‐order structural model is employed to generate the numerical output via multi‐stripe analysis, thus enabling the evaluation of the pertinent record selection approaches. Focusing on uplift and compressive meridional stress, response ratios and response hazard curves are extracted. It is shown that although the vertical ground motion component only mildly affects uplift, its effect on compressive meridional stress, on average, amplifies the response by a factor of 1.8 for moderate intensities and 2.8 for higher ones. Accounting for hazard consistency in the vertical component appears to be important for the case at hand, as it reveals notable discrepancies in the mean annual frequency of exceedance for the response parameters examined.
Extremely High Soil Copper Content, yet Low Phytotoxicity: A Unique Case of Monometallic Soil Pollution at Kargaly, Russia
Authors: Dovletyarova Elvira A. , Zhikharev Alexander P. , Polyakov Dmitry G. , Karpukhin Mikhail M. , Buzin Igor S. , Yáñez Carolina , Neaman Alexander 
Published: January 2023

Abstract
Ecotoxicological studies on soil metal toxicity often rely on artificially contaminated soils. A major difficulty in using soils contaminated by anthropogenic activities (e.g., mining and agriculture) is the presence of multiple metals, which can make it impossible to distinguish the toxic effects of a particular metal. Therefore, sites with monometallic pollution have great potential for ecotoxicological research. One such site is an agricultural field in Kargaly, Orenburg region, Russia, where copper mining and smelting activities were carried out during the 18th–20th centuries. Samples of Mollisols (chernozems) were collected in the studied field. At several sampling points there were copper ore rocks on the surface, containing malachite (CuCO3 · Cu(OH)2). The soil samples had a high copper content, up to approximately 10 g kg−1, compared with 75 mg kg−1 in the background soil. Importantly, the content of other elements in all soil samples was similar to that in the background soil, highlighting the uniqueness of the monometallic contamination in the study area. Despite the extremely high total copper content, exchangeable copper was relatively low, with a maximum of approximately 0.5 mg kg−1. We performed a short-term (21-day) ecotoxicity assessment using perennial ryegrass as an indicator of copper toxicity. Contrary to expectations, plant growth was not affected by the high copper content in the studied soils. The low copper phytotoxicity may be explained by the low solubility of malachite. However, future long-term experiments may be warranted to determine copper toxicity thresholds for plants under field conditions. The site discovered in the present study could potentially acquire the same significance as the Danish Hygum site for the study of monometallic soil contamination. Environ Toxicol Chem 2023;42:707–713. © 2023 SETAC
Broadening the Perspective on Reducing Pharmaceutical Residues in the Environment
Authors: Helwig K. , Niemi L. , Stenuick J.-Y. , Alejandre J. C. , Pfleger S. , Roberts J. , Harrower J. , Nafo I. , Pahl O. 
Published: January 2023

Abstract
The present study reviews options for reducing harm from pharmaceuticals that are known to cause adverse impacts by their presence in the environment. It reviews recent global and European Union policy development, which could go further in recognizing and addressing the issue in a global context. It considers green chemistry, which can help clean up production processes but holds only long-term promise for creating “green” alternatives. It explores the potential of health promotion and disease prevention, which can contribute significantly to a reduction of the disease burden and thus the need for medicines, both for infectious and for noncommunicable disease. Eco-directed sustainable prescribing practices are reviewed, which have been adopted successfully to reduce the use of harmful pharmaceuticals. We note recent developments in medicines optimization and precision medicine, which hold promise for improving patient outcomes, saving costs, and reducing pharmaceutical use, through individually tailored prescribing whereby the patient codecides their therapy. Waste prevention through reuse or redistribution is beginning to find public support and “take-back” waste disposal schemes set up via extended producer responsibility systems have achieved high returns. Finally, the paper summarizes preferred advanced wastewater technologies, including innovative low-cost, low-energy options. In summary, although end-of-pipe options have a role to play, particularly for highly concentrated wastewaters, solutions further up the medicinal chain and disease prevention interventions, informed by a broad view of health and health care, are needed to pursue a much greater potential reduction of pharmaceuticals in the environment than can be achieved by end-of-pipe solutions alone. Environ Toxicol Chem 2024;43:653–663. © 2023 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC.
Nanocelluloses review: Preparation, biological properties, safety, and applications in the food field
Authors: He Hong , Teng Hui , An Fengping , Wang Yiwei , Qiu Renhui , Chen Lei , Song Hongbo 
Published: January 2023

AbstractFunctional diet and food safety requirements, as well as reducing the consumption of nonrenewable resources and environmental pollution are the important development themes on food processing. The development and application of edible nanocelluloses (NCs) is an urgent need in the current food field. NCs are divided into three types, including cellulose nanofibrils, and cellulose nanocrystals from natural fibers, as well as bacterial cellulose synthesized by bacteria. In this review, recent developments in surface modification, biological properties, safety issues, and their applications in the food industry were highlighted. NCs have application limits due to native hydrophilicity, surface modification strengthens their hydrophobicity and stability in the oil phase. NCs exhibit excellent physicochemical properties and successfully be used as edible coatings, emulsion stabilizers, and functional food ingredients. In particular, NCs and modified NCs can be used as low‐calorie fat substitutes and prebiotics for improving gut microbiota. However, the biological properties and safety assessments still require more attention, as well as establishing the regulations for food applications.
Crustal study based on integrated geophysical techniques in the Northwestern Himalayas, Pakistan
Authors: Hameed Fahad , Khan Muhammad Rustam , Dentith Michael 
Published: January 2023

The present research aims to explicate the tectonics of the northwest Himalayas, Pakistan, based on integrated gravity, magnetic and earthquake data. The raw gravity and magnetic data were processed, and seven isoanomaly maps were prepared for qualitative interpretation, whereas a gravity model was prepared along the selected profile for quantitative interpretation. The local earthquake data have also been used to identify the various seismogenic layers in the subsurface and to understand how seismicity relates to regional structural features. Three northwest‐trending thick‐skinned blind basement faults are identified from the present study, namely the Indus Kohistan Seismic Zone (IKSZ), Bagh Basement Fault and Hazara Lower Seismic Zone. The IKSZ is the tectonically most active among them and responsible for the 2005 Kashmir earthquake (Mw = 7.6) and 1974 Pattan earthquake (Mw = 6.2) in the region. The present study also delineated the prominent location of the Main Central Thrust in which the high‐grade metamorphic rocks of Higher Himalayan Crystalline thrust over low‐grade metamorphic rocks of Lesser Himalayas along this thick‐skinned fault. The field evidence such as ductile deformation, zone of inverted metamorphism, and brittle deformation also confirm this location. The sharp bending of the crystalline crust, as well as deep basement just south of Kohistan Island Arc (KIA), indicate that the high density and susceptibility rocks of this arc thrust on the leading margin of the Indian Plate along the Main Mantle Thrust. This thrust fault is a major suture zone separating the KIA in the north from the Indian Plate in the south. The other faults in the region exist in the sedimentary/meta‐sedimentary wedge and are thin‐skinned. It is inferred from the current investigation that the study area exhibits a composite style of deformation. Moreover, the gravity model combined with earthquake data suggested the existence of multiple décollement zones below the Hazara‐Kashmir Syntaxis. The model envisaged an increase in the thickness of the Indian Plate continental crust in the northeast direction.
Unravelling neurotransmitters impairment in primary progressive aphasias
Authors: Premi Enrico , Dukart Juergen , Mattioli Irene , Libri Ilenia , Pengo Marta , Gadola Yasmine , Cotelli Maria , Manenti Rosa , Binetti Giuliano , Gazzina Stefano , Alberici Antonella , Magoni Mauro , Koch Giacomo , Gasparotti Roberto , Padovani Alessandro , Borroni Barbara 
Published: January 2023

AbstractPrimary progressive aphasias (PPAs) are a group of neurodegenerative diseases mainly characterized by language impairment, and with variably presence of dysexecutive syndrome, behavioural disturbances and parkinsonism. Detailed knowledge of neurotransmitters impairment and its association with clinical features hold the potential to develop new tailored therapeutic approaches. In the present study, we applied JuSpace toolbox, which allowed for cross‐modal correlation of magnetic resonance imaging (MRI)‐based measures with nuclear imaging derived estimates covering various neurotransmitter systems including dopaminergic, serotonergic, noradrenergic, GABAergic and glutamatergic neurotransmission. We included 103 PPA patients and 80 age‐matched healthy controls (HC). We tested if the spatial patterns of grey matter volume (GMV) alterations in PPA patients (relative to HC) are correlated with specific neurotransmitter systems. As compared to HC, voxel‐based brain changes in PPA were significantly associated with spatial distribution of serotonin, dopamine, and glutamatergic pathways (p < .05, False Discovery Rate corrected‐corrected). Disease severity was negatively correlated with the strength of GMV colocalization of D1 receptors (p = .035) and serotonin transporter (p = .020). Moreover, we observed a significant negative correlation between positive behavioural symptoms, as measured with Frontal Behavioural Inventory, and GMV colocalization of D1 receptors (p = .007) and serotonin transporter (p < .001). This pilot study suggests that JuSpace is a helpful tool to indirectly assess neurotransmitter deficits in neurodegenerative dementias and may provide novel insight into disease mechanisms and associated clinical features.
An Unusual Fullerene–Carbene Adduct: Thermal Motion, Disorder, or Both?**
Authors: Carreras Abel , Lorbach Andreas , Bazan Guillermo C. , Alemany Pere , Wu Guang , Garcia‐Garibay Miguel A. , Maverick Emily F. 
Published: January 2023

AbstractA single‐crystal X‐ray study of a fullerene‐imidazole adduct at nine temperatures (80 K≤T≤480 K), accompanied by energy calculations, strongly suggested thermal motion of the C60 moiety with respect to the imidazolium heterocycle. Analysis of the anisotropic displacement parameters, calculations of frequencies, and the refinement of disorder models for the crystal at four temperatures (230 K≤T≤380 K) lead to the conclusion that the rotator is moving at all temperatures. The rotation barrier is low, with one preferred crystallographic site and several other energy minima.
Extreme risk spillovers across energy and carbon markets: Evidence from the quantile extended joint connectedness approach
Authors: Cao Guangxi , Xie Fei 
Published: January 2023

AbstractExtreme events have further complicated the already closely related carbon‐energy system, but little research has focused on the extreme spillovers between energy and carbon markets. This paper combines quantile vector autoregression with the extended joint connectedness approach to introduce a new quantile extended joint connectedness approach to study the extreme spillover between the carbon market, fossil energy and clean energy markets, using daily data spanning from October 15, 2010 to February 25, 2022. The results show that markets are more closely linked at extreme risk, and the spillover is time‐varying and cyclical. The impact of extreme events will strengthen the links between markets. Further research shows different clean energy have heterogeneous spillovers on the carbon market, especially when impacted by extreme events. Finally, the hedging and portfolio effectiveness of clean energy to carbon market also show the existence of heterogeneity, and clean energy can diversify the portfolio of carbon market.
Coping and sleep quality in youth: An Experience Sampling study
Authors: Hagemann Noëmi , Kirtley Olivia J. , Lafit Ginette , Vancampfort Davy , Wampers Martien , Decoster Jeroen , Derom Catherine , Gülöksüz Sinan , De Hert Marc , Jacobs Nele , Menne‐Lothmann Claudia , Rutten Bart P. F. , Thiery Evert , van Os Jim , van Winkel Ruud , Wichers Marieke , Myin‐Germeys Inez 
Published: January 2023

AbstractIntroductionSleep quality is closely linked with mental health. Two factors that influence sleep are coping style and locus of control, yet these have not been investigated in daily life. In this study, we examined associations between coping styles and sleep quality in daily life and the potential mediating effect of daily locus of control in a sample of youth, a group particularly vulnerable to developing psychopathology.MethodsThree hundred and seventy‐nine youths from the TwinssCan study participated in an Experience Sampling study, assessing sleep quality as well as state locus of control over the most negative event from the previous day. Participants also completed the Utrecht Coping List, which assessed engagement, disengagement, and emotion‐focused coping.ResultsDisengagement, “passive reaction,” and emotion‐focused coping were associated with lower daily sleep quality. State locus of control did not mediate any effects of coping styles on quality of sleep.ConclusionsDisengagement, “passive reaction,” and emotion‐focused coping were associated with decreased sleep quality during several consecutive days, which may put youths at risk for developing future insomnia, and strain their mental well‐being over time. Thus, there may be value in asking about coping when a young individual presents with sleep problems; however, impaired coping when sleeping poorly should also be considered.
The landscape of endodontic education research area: A bibliometric analysis
Authors: Fu Di , Yao Lin , Zhu Hualing , Yan Yujia , Ji Mengzhen , Li Yanyao , Chi Yaqi , Wang Ye , Liao Ga , Zou Ling 
Published: January 2023

AbstractObjectivesEducational research is essential for rationalizing curriculum design, improving evaluation systems, and updating teaching content. This bibliometric study aimed at analyzing the characteristics of publications relevant to endodontic education, thus forming a comprehensive scope of this research area.MethodsThe search was conducted in the Web of Science Core Collection database in May 2022. Knowledge units of the included publications, such as year of publication, journal, country/institution/author, keywords, and highly cited articles/references, were analyzed.ResultsThe United States ranked first in the number of articles with a total of 17 articles. The majority of included articles were published in Journal of Dental Education (n = 25), International Endodontic Journal (n = 21), and European Journal of Dental Education (n = 14). The top 3 most frequent keywords were Endodontics, Education, and Root canal treatment. The main topic in endodontic education were curriculum, preclinical education, educational technology, and continuing education.ConclusionForming a full scope of the endodontic research area, this bibliomertic
analysis can help mine the hot topic, predict the frontiers in the field and provide the data necessary to determine the direction of research, rationalize resource allocation, and formulate policy.
UK and Spanish stranger sexual offenders crime scene behaviours and previous convictions: A cross‐cultural comparison
Authors: Almond Louise , Rainbow Lee , Ramos Romero Manuel , Giles Susan , McManus Michelle , Nikolajeva Anastasia 
Published: January 2023

AbstractInternational comparisons of previous convictions (PC) and crime scene behaviours (CSB) of stranger sexual offences can inform offender profiling strategies; especially the degree to which pragmatic models cross validate across countries. The present study compared PC and CSB of 474 UK and 418 Spanish cases. CSB and PC were analysed using Chi‐square. UK stranger sexual offenders displayed a higher proportion of all CSB analysed. UK offenders also had a significantly higher proportion of PC with the exception of violence offences. There were no significant differences in sexual pre‐convictions. In both the UK and Spain the CSB ‘reference to the police’ was significantly association with the PC ‘Criminal damage’ no other similar significant associations were found. Explanations for these findings include differences between the countries in regards to: legislation, crime recording processes, data coding processes, with additional consideration of any cultural, environmental and contextual factors.
The association of astrogliosis and microglial activation with aging and Alzheimer's disease pathology in the chimpanzee brain
Authors: Edler Melissa K. , Munger Emily L. , Maycon Hannah , Hopkins William D. , Hof Patrick R. , Sherwood Chet C. , Raghanti Mary Ann 
Published: January 2023

AbstractAging and neurodegenerative disorders, such as Alzheimer's disease (AD), trigger an immune response known as glial activation in the brain. Recent evidence indicates species differences in inflammatory responses to AD pathology, highlighting the need for additional comparative studies to further understand human‐specific neuropathologies. In the present study, we report on the occurrence of astrogliosis, microglial activation, and their relationship with age and AD‐like pathology in a cohort of male and female chimpanzees (Pan troglodytes). Chimpanzees with severe astrogliosis exhibited widespread upregulation of hypertrophic astrocytes immunoreactive for glial fibrillary acidic protein (GFAP) throughout all layers of the dorsolateral prefrontal cortex and a loss of the interlaminar palisade. In addition, extreme astrogliosis was associated with increased astrocyte density in the absence of significant microglial activation and AD lesions. A shift from decreased resting to increased phagocytotic microglia occurred with aging, although proliferation was absent and no changes in astrogliosis was observed. Vascular amyloid correlated with decreased astrocyte and microglia densities, while tau lesions were associated with morphological changes in microglia and greater total glia density and glia: neuron ratio. These results further our understanding of inflammatory processes within the chimpanzee brain and provide comparative data to improve our understanding of human aging and neuropathological processes.
Development and Internal Validation of a Prediction Model for Difficult Laryngoscopy Using Ultrasound‐Derived Factor in Comatose Patients
Authors: Li Yueying , Li Jingye , Zhong Liping , Zeng Zhiwen 
Published: January 2023

ObjectivesThe distance from skin to the hyoid bone (DSHB) and skin to the anterior commissure of vocal cords (DSAC) are reliable parameters for pre‐operative airway ultrasound assessment in awake patients and can be assessed in comatose patients. This study aimed to inspect its feasibility and accuracy in predicting difficult laryngoscopy for comatose patients.MethodsA prospective cohort study included patients with a Glasgow Coma Scale (GCS) of ≤8 who underwent emergency tracheal intubation between November 2019 and August 2020. The outcome was difficult laryngoscopy and classified according to the Cormack–Lehane grading.ResultsA total of 151 patients were included in the study. Fifty‐two (34.4%) patients were categorized as having difficult laryngoscopy. The DSHB add DSAC (hereinafter referred to as the “DSBAC”) was superior to either parameter alone in the predictive performance, and the optimal cut‐off value was 1.90. To optimize the predictive value, DSBAC (adjusted odds ratio [OR]: 7.76; 95% confidence interval [CI]: 2.88–20.94; P < .001), GCS (adjusted OR: 1.39; 95% CI: 3.93–26.28; P = .039), mandibular retraction (adjusted OR: 8.20; 95% CI: 1.92–35.09; P = .005) and edentulous (adjusted OR: 4.23; 95% CI: 1.40–12.80; P = .011) were included in a multivariable model and constructed a nomogram. Discrimination and calibration statistics were satisfactory, with C‐index above 0.80 from both model development and internal validation.ConclusionsUltrasound‐derived factor, DSBAC, can be easily assessed and help predict difficult laryngoscopy among comatose patients. A simple nomogram including only four clinical items exhibited excellent discrimination performance and was useful when comatose patients underwent emergency tracheal intubation.
The relationship between learning orientation and new product development capability
Authors: Moreno Espinoza Paola Andrea , Sparano Martins Tomas , Gomes Paulo Morilha Lanzarini 
Published: January 2023

AbstractThe objective of this paper is to analyze the mediating effect of new product development capability on the relationship between learning orientation and financial performance. The research was applied in SMEs that belong to the Personal Hygiene and Cosmetic Industry in Brazil. There are 226 cases in the sample and the method used to test the relations between the hypotheses was the Structural Equation Modeling. The results showed us that learning orientation positively influences financial performance; there is a significant positive relationship between learning orientation and new product development capability; new product development capability has a positive influence on the financial performance; and there is a partial mediating effect of the new product development capability on the relationship between learning orientation and financial performance.