bluuebunny/crossref_metadata_2025_split huggingface dataset:
Longitudinal Quantitative Assessment of Retinal Crystalline Deposits in Bietti Crystalline Dystrophy
Authors: You Seung Jun , Yoon Chang Ki , Park Un Chul , Park Kyu Hyung , Lee Eun Kyoung 
Published: January 2025

Abstract

Background
This study aims to quantitatively analyze retinal crystalline deposits in patients with Bietti Crystalline Dystrophy (BCD) and examine their progression over time in a longitudinal study.
Methods
We retrospectively reviewed consecutive patients diagnosed with BCD at a single center. Retinal crystalline deposits were quantified from fundus photographs using semi-automated software, which divided the macular area into a central foveal circle, inner ring, and outer ring. We then analyze changes in the amount and intensity of these deposits over a two-year period.
Results
The study included 30 eyes from 16 patients. Mean crystal intensity was 1.158 ± 1.425% in the central foveal circle, 1.043 ± 1.444% in the inner ring, and 0.990 ± 0.969% in the outer ring, with no significant differences observed between the regions (all P > 0.05). Over the two-year study period, there was a gradual decrease in both the amount and intensity of the crystals in all zones. However, these changes were not statistically significant (all P > 0.05).
Conclusions
The use of semi-automated software to analyze fundus photographs provided a quantitative method for assessing retinal crystalline deposits in BCD. This longitudinal study enhanced our understanding of the disease’s natural progression.
Hospital-Based Analysis of Early-Onset Diabetes in Ghana's Upper East Region: Prevalence, Complications, and Challenges
Authors: Solomon Beletaa , Kaba Ceasar , Mensah Joy Afua , Helegbe Gideon Kofi , Abugri James , Adadey Samuel Mawuli 
Published: January 2025

Abstract

Diabetes mellitus is the most prevalent endocrine disorder in individuals under 30 years, encompassing type 1 diabetes mellitus (T1DM), early-onset type 2 diabetes mellitus (T2DM), monogenic diabetes, and maturity-onset diabetes of the young (MODY). This study investigated the prevalence, diagnosis, types, and complications associated with early-onset diabetes in Ghana, utilizing hospital data from 52 patients under 30 years of age. Among them, 20 patients were under 20 years. T1DM was diagnosed in 15 patients, while only one case of T2DM was identified. Secondary diabetes with unknown etiologies was the most common diagnosis (22 cases), indicating the potential presence of undiagnosed monogenic diabetes or MODY. Reported complications included diabetic foot (5 cases), diabetic nephropathy (2 case), infections (4 cases), retinopathy (4 cases) and ketoacidosis (13 cases). While most patients recovered and were discharged, 3 deaths, 1 referral, and 1 absconded case were recorded. These findings highlight the importance of accurate diagnosis, targeted management strategies, and further research into secondary diabetes and its potential underlying causes in Ghana. The study underscores the need for improved diagnostic capabilities, awareness, and healthcare resources to address early-onset diabetes and its complications in the country.
The Role of Mid Regional Pro-adrenomedullin as a Biomarker for Early Cardio-Renal Dysfunction in Prediabetes and Type 2 Diabetes Mellitus _ A Prospective cohort study
Authors: Rao Oshmi , Kumar J.S. 
Published: January 2025

Abstract

Background:Cardiovascular and renal complications are leading causes of morbidity and mortality in patients with Prediabetes type 2 diabetes mellitus (T2DM). Identifying reliable biomarkers for early detection of cardio-renal dysfunction is essential to mitigate disease progression and improve clinical outcomes. This prospective cohort study evaluates the association between serum Mid-Regional Pro-adrenomedullin (MR-ProADM) levels and early signs of endothelial dysfunction in patients with prediabetes and T2DM.
Method: The study was conducted at SRM Medical College Hospital and Research Centre, involving 90 participants divided equally into prediabetic and T2DM groups. Comprehensive clinical assessments included measurements of MR-ProADM, NT-ProBNP, eGFR, urine albumin-to-creatinine ratio (ACR), lipid profiles, and glycated hemoglobin (HbA1c). All these petameters are measured at baseline as well as after 1 year of follow-up.
Finding: The study observed a significant increase in serum MR-ProADM levels in prediabetic and T2DM patients during follow-up compared to baseline. MR-ProADM correlated positively with early markers of endothelial dysfunction and cardio-renal impairment. Linear regression analysis confirmed strong associations with NT-ProBNP, Ejection fraction, eGFR, and ACR, indicating its potential as a predictive biomarker for cardiovascular and renal complications. ROC curve analysis further validated MR-ProADM’s diagnostic utility in identifying patients at risk. This study highlights MR-ProADM’s clinical relevance as a stable, reliable marker for early detection, risk assessment, and timely intervention in prediabetic and T2DM populations.
Interpretation: Serum MR-ProADM shows potential as a reliable biomarker for early detection of cardio-renal dysfunction in prediabetes and T2DM. Its significant correlation with NT-ProBNP, Ejection fraction, eGFR, and ACR highlights its utility in predicting cardiovascular and renal complications, enabling timely intervention to improve clinical outcomes.
The Role of Emerging Technologies in Sports Law: Legal Challenges and Opportunities
Authors: Asiabar Mojtaba Ghorbani , Asiabar Morteza Ghorbani , Asiabar Alireza Ghorbani 
Published: January 2025

Abstract

This study examines the profound impact of emerging technologies on sports law, highlighting both the challenges and opportunities they present. The rapid advancement of digital platforms, artificial intelligence, and data analytics has revolutionized the sports industry, necessitating a reevaluation of existing legal frameworks. Our research employs a mixed-methods approach, combining qualitative analysis of legal cases with quantitative data from a survey of 500 sports law professionals (n = 500, p < 0.05). Key findings reveal that 78% of respondents identify data privacy and athlete biometric information as the most pressing legal concerns. The study also explores the legal implications of virtual and augmented reality in sports, with 65% of participants anticipating significant changes in intellectual property rights within the next five years. Additionally, we analyze the potential of blockchain technology in enhancing transparency in sports contracts and anti-doping measures. Our results indicate a statistically significant correlation (r = 0.72, p < 0.01) between the adoption of new technologies and the complexity of legal challenges faced by sports organizations. This research contributes to the growing body of literature on sports law and technology, providing valuable insights for legal practitioners, policymakers, and sports administrators navigating this rapidly evolving landscape.
Detection And Grading of Rust Disease Severities from Wheat Images Using Deep Learning Techniques
Authors: Muhammadnur Jibril , Meshesha Million , Abate Jemal , Aman Araba 
Published: January 2025

Abstract

Wheat production, a cornerstone of food security in Ethiopia, is heavily impacted by stripe rust disease, which leads to significant economic losses. Traditional methods for detecting and classifying disease severity are labor-intensive, error-prone, and costly. This study introduces a novel convolutional neural network (CNN)-based model, WRNet, designed for the detection and severity classification of wheat yellow rust disease, along with treatment recommendations. Utilizing 20,000 annotated images collected from Ethiopia, the model applies advanced preprocessing techniques such as noise removal and segmentation using bilateral filtering and k-means algorithms. The WRNet model achieved superior performance with 99.11% training accuracy, 99.04% validation accuracy, and 99% testing accuracy, surpassing pre-trained models such as InceptionV3, InceptionResNetV2, and MobileNetV2. Additionally, the system provides fungicide dosage recommendations tailored to severity levels, ensuring effective disease management. A user-friendly prototype interface developed using Flask enables domain experts to classify disease severity and receive treatment recommendations, offering a scalable solution for precision agriculture in Ethiopia and beyond.
Determining the Factors that Influence Online Purchase Intentions at Shopee Indonesia with Trust as Mediation
Authors: Solihin Dede , Ahyani Ahyani 
Published: January 2025

Objectives: This research was conducted to determine the factors that influence online purchasing intentions at Shopee Indonesia with Trust as Mediation.Methodology: This research uses quantitative methods with a casual design. The population in this research is all Shopee users in South Tangerang. The sampling technique used a purposive sampling method with a sample size of 120 people. Data was collected using a questionnaire and then analyzed using statistical tests using the SEM (Structural Equation Modeling) method using PLS 3.0 software.Finding: The research results show that perceived usefulness, Perceived Ease, and perceived risk have a significant effect on trust. Trust has a significant effect on Purchase Intention. Perceived usefulness has a significant effect on purchase intention. Perceived Ease does not have a significant effect on Purchase Intention. Risk Perceived has a significant effect on Purchase Intention. Trust has not been able to mediate the influence between Perceived Usefulness on Purchase Intentions. Trust can mediate the influence of Perceived Ease of Convenience on Purchase Intentions. Trust has not been able to mediate the influence between Risk Perceived on Purchase Intentions.Conclusion: The Trust variable has not been able to mediate the relationship between Perceived Usefulness and Perceived Risk on Purchase Intentions, however, the Trust variable can mediate the relationship between Perceived Ease on Purchase Intentions. Perceived Ease does not have a significant effect on Purchase Intention. Thus, to minimize the risks that occur when shopping online, companies must be able to maintain and increase consumer confidence in online transactions.
Apostándole al arte como fundamento de las apuestas lúdico-pedagógicas: Un camino hacia la inclusión y el fortalecimiento de la equidad educativa en el proceso de enseñanza-aprendizaje
Authors: Guevara Lasso Alejandra , Oyola Juan Guillermo , Aguas Briyith Brisbana 
Published: January 2025

El ámbito educativo, puntualmente en el sector rural, se ha visto seriamente afectado por un sistema educativo que los rige a todos por igual, pero que desafortunadamente no garantiza una educación con los mismos beneficios para todos y todas, desde el reconocimiento de la diversidad y la equidad como pilares en el accionar docente e institucional.
La presente apuesta investigativa nace entonces desde el interés por fortalecer los procesos de enseñanza-aprendizaje con estudiantes en edades de 6 a 8 años que presentan dificultades del aprendizaje de la Institución educativa rural El Poblado del Municipio de Puerto Asís, a través de la guía lúdico-pedagógica “EquiGuía”, buscando favorecer así, la equidad educativa. La investigación se realiza bajo un enfoque Cualitativo, que permita de manera confiable hallar la información a partir de la lectura de la realidad, corroborando los resultados, y ejecutando una propuesta de acción, para finalmente valorar la efectividad de las acciones gestadas y realizar un proceso y análisis reflexivo del proceso, todo ello bajo la mirada de la Investigación acción participante.
De otro lado, la apuesta investigativa permitió reconocer aportes sobre la importancia de la educación en el ámbito social; para comprender las realidades de la educación rural desde el reconocimiento de la diversidad y la equidad como pilares en el accionar docente e institucional, se debe dar una mirada holística al fenómeno.Por lo anterior, se considera como elemento principal de las estrategias de enseñanza y aprendizaje, el desarrollo de los procesos de aula, a través de métodos lúdicos, estos resaltan elementos pedagógicos positivos, debido a sus características: la variedad en los procesos pedagógicos, didácticas divertidas, goce de las actividades, entre otros, que generan ambientes de aprendizaje agradables a las y los estudiantes mientras desarrollan habilidades cognitivas como capacidad de análisis, reflexión, interpretación y co-construcción de contenidos, algo que puede ser casi imposible de adquirir con técnicas tradicionales de estudio.
En concordancia, sin duda el desinterés de los estudiantes, se debe convertir en un elemento preocupante para los docentes ya que es un indicador de la baja efectividad de los actuales procesos pedagógicos, a los estudiantes se les debe motivar, incentivar y estimular con estrategias lúdico-pedagógicas acorde a sus características, intereses y/o necesidades, pero las estrategias tradicionales y rutinarias, solo han generado desánimo y desinterés por parte de los estudiantes a su entorno escolar, quienes deben ser la mayor motivación para la generación estudiantes integrales con capacidades y habilidad que les permita desarrollarse de la manera más adecuada en sociedad.
Pengaruh Pendekatan Student Centered Learning (SCL) Terhadap Hasil Belajar pada Mata Kuliah Morfologi Tumbuhan
Authors: Lely Lely Pratiwi , Marjanah  , Tri Mustika Sarjani  
Published: January 2025

Pendidikan saat ini menuntut peserta didik untuk lebih aktif dan mandiri dalam pembelajaran. Sehingga, digunakan pendekatan Student Centered Learning (SCL) sebagai salah satu pendekatan yang dapat memenuhi capaian tersebut, disebabkan pendekatan Student Centered Learning (SCL) memusatkan peserta didik sebagai pelaku utama dalam proses pembelajaran. Penelitian ini bertujuan untuk mengetahui pengaruh dan hasil belajar pada pendekatan Student Centered Learning (SCL). Metode yang digunakan adalah metode eksperimen. Rancangan penelitian yang digunakan adalah Pretest-Posttest Control Group Design dengan menggunakan dua sampel yaitu kelas eksperimen dan kelas kontrol. Sampel dalam penelitian ini berjumlah 17 mahasiswa kelas eksperimen dan 15 mahasiswa kelas kontrol. Instrumen yang digunakan berupa soal pilihan berganda berjumlah 20 soal. Nilai rata-rata hasil belajar kelas eksperimen sebesar 79,21 dan kelas kontrol 60,23 maka selisihnyasebesar 18,98. Hasil pengujian hipotesis hasil belajar dengan uji t (α = 0,05) diperoleh Thitung (6,316) > Ttabel (2,042). Berdasarkan hasil tersebut didapatkan bahwa penerapan pendekatan Student Centered Learning (SCL) memiliki pengaruh yang signifikan terhadap hasil belajar mahasiswa. Hal ini terjadi, karena pendekatan Student Centered Learning (SCL) mendorong pembelajaran secara aktif yang dapat mengembangkan kemampuan peserta didik untuk lebih kreatif dan mandiri dalam proses pembelajaran sehingga dapat meningkatkan hasil belajar.
Solar Drying and Bioethanol Production From Agro-Industrial Banana (musa paradisiaca l.) Residues
Authors: Santis-Espinosa Luis Fernando , López-Vidaña Erick C. , Hernández‑Altamirano R. , Grajeda Juan M. Sierra , Aguilar-Aguilar F.A. , Sebatian P. J. 
Published: January 2025

Objectives: The objective of this study is to investigate biomass sources that may be potential for bioethanol production, as well as the impact of using solar energy for dehydration of raw materials in the process of preserving carbohydrates for alcoholic fermentation. As well as to evaluate the potential of banana waste for bioethanol production by solar drying and three different pretreatment methods: acid hydrolysis, sterilization and pasteurization.

Theoretical Framework: Banana (Musa paradisiaca L.) residues, rich in fermentable sugars, present a valuable yet underutilized feedstock for this purpose.

Method: In this study the banana residues were first dehydrated using solar dryers, followed by analysis of their sugar composition using high-performance liquid chromatography (HPLC).

Results and Discussion: The sugar analysis revealed significant levels of fructose (16.5 g/L) and glucose (15.01 g/L), key substrates for ethanol fermentation. Pretreatment methods were compared based on their effectiveness in enhancing bioethanol yields. Acid hydrolysis at pH 4.5 produced the highest bioethanol concentration of 55.18 g/L, demonstrating the effectiveness of acid treatment in breaking down complex sugars. Sterilization also yielded promising results, with a maximum ethanol production of 64.26 g/L at pH 5.0, showing consistency across different pH levels. Pasteurization, while less efficient, still produced 34.11 g/L of ethanol at pH 4.5, highlighting its potential in low-intensity processes. The solar drying process effectively reduced the moisture content of banana residues by up to 88.6%, maintaining the integrity of fermentable sugars.

Research implications: The drying kinetics were influenced by solar irradiance, with faster moisture removal observed during peak sunlight hours.

Originality/value: The study demonstrates that banana residues are a promising feedstock for bioethanol production, with acid hydrolysis and sterilization offering the best results in terms of bioethanol yield.
The Human Factor in The Problems, Challenges and Solutions of Implementing Technologies in Recycling Networks
Authors: Lima Ana Paula Freitas De , Giglio Ernesto Michelangelo 
Published: January 2025

Objective: The objective is to investigate the problems, challenges and solutions of implementing technologies in recycling networks found in the analysis of research sources, based on a proposition.

Theoretical Framework: In this topic, the main concepts and theories that underpin the research are presented. The theories of network formation, principles of circular economy and principles of technology adoption theory stand out.

Method: The research is qualitative and exploratory due to the rarity of bibliographic production. A matrix of indicators was produced and research was carried out in secondary sources of documents and media, and primary sources of interviews.

Results and Discussion: The data supports the proposition that problems and challenges are found on the human side, because technologies exist. There is a lack of environmental education, business commitment and good government governance.

Research Implications: The results imply knowledge about resistance and solutions for adopting recycling technologies, paving the way for new research and possible management actions.

Originality/Value: A matrix of results is offered, which organizes the problems, challenges and solutions throughout the stages of recycling and environmental and human variables, presenting a practical contribution to future research and policies to encourage the circular economy.
TRILOGÍA DE NOVELAS DE CARLOS SEPÚLVEDA LEYTON: LA LITERATURA COMO HERRAMIENTA PARA LA HISTORIOGRAFÍA DEL PROFESORADO CHILENO
Authors: Fernández Llanos Belén 
Published: January 2025

El artículo toma como objeto de estudio la trilogía de novelas de Carlos Sepúlveda Leyton, profesor normalista y representante de la Asociación General de Profesores de Chile (AGP). La trilogía está compuesta por las novelas autobiográficas Hijuna… (1934), La Fábrica (1935) y Camarada (1938), las cuales fueron analizadas en dos niveles narrativos: en primer lugar, la escritura de las experiencias alusivas a la escuela, a la formación/profesión docente y al movimiento político pedagógico de la AGP; en segundo lugar, los recursos narrativos utilizados por el autor para dar cuenta de dichas experiencias. La trilogía de Carlos Sepúlveda Leyton es un caso de Novelas de formación docente, en tanto muestra el desarrollo de un personaje al interior de la escuela primaria, la Escuela Normal de Preceptores y luego en su ejercicio como maestro. El estudio propone la utilidad de este y otros materiales literarios para reconstruir la historia del profesorado chileno, a partir de las narrativas autobiográficas de sus docentes.
PRESENCIA DE LAS HABILIDADES DEL PENSAMIENTO MATEMÁTICO EN EVALUACIONES DE 4o BÁSICO. INVESTIGACIÓN EN CONTEXTO DE APROPIACIÓN CURRICULAR
Authors: Palacios Donoso Marcelo Manuel 
Published: January 2025

El presente artículo da cuenta del primer año de formación de comunidades de docentes de educación básica que imparten la asignatura de matemáticas en la región de Valparaíso por parte del Departamento de Educación Regional a partir de 2017, el cual incorpora un proceso investigativo cuyo objetivo estratégico es la apropiación curricular de docentes mediante reflexión y análisis de los programas. Para ello se analiza la relación entre ítems correspondientes a la unidad de número y operaciones de 4o básico con las exigencias curriculares del desarrollo de habilidades propias del pensamiento matemático. El proceso implica la revisión de diversos elementos de política pública centrados en la demanda curricular, el rol docente y su evidencia en la evaluación.
Metodológicamente se opta por la perspectiva interpretativa-cualitativa, utilizando la técnica de análisis de contenido temático para analizar los ítems. Los resultados obtenidos señalan una baja presencia de las habilidades matemáticas en los ítems analizados, siendo la más baja la de argumentar y comunicar, por lo que este artículo busca aportar al conocimiento de equipos técnicos internos y externos a la escuela, pero por sobre todo a la toma de conciencia sistémica del carácter urgente que tiene una adecuada apropiación curricular para la asignatura de matemáticas.
Crisis socioecológicas y educación popular ambiental en el mundo rural: la relevancia de Paulo Freire para los estudios críticos de la comunicación ambiental y la educación para el desarrollo sostenible
Authors: Alarcon Ferrari Cristian Edmundo 
Published: January 2025

Este artículo pretende contribuir a la reexión en torno a la relevancia del trabajo de Paulo Freire al pensar problemas pedagógicos y educativos en el mundo rural en el contexto de las múltiples crisis socioecológicas del presente y en la perspectiva de un análisis crítico de los campos de estudio de la educación para el desarrollo sostenible y la comunicación ambiental. Para ello se presenta una lectura en perspectiva del ensayo de Freire ¾Extensión o comunicación? La concientización en el medio rural, en la que se utilizan ejemplos de experiencias pedagógicas y de investigación con foco en temas de sustentabilidad y ruralidad. El artículo discute y propone algunos de los aportes de Freire para la construcción política de la educación popular ambiental en el mundo rural actual.
Memorias del presente.
Authors: Garriga María Cristina , Pappier Viviana 
Published: January 2025

Quienes escribimos este trabajo formamos parte de la cátedra de Planificación Didáctica y prácticas de la enseñanza en Historia, del Profesorado de Historia de la Facultad de Humanidades y Ciencias de la Educación de la Universidad Nacional de la Plata, cuyo propósito consiste en abordar la complejidad de la práctica docente, atravesada por múltiples subjetividades, saberes y tradiciones y diseñar herramientas para teorizar conjuntamente con los estudiantes.
Desde nuestro lugar como docentes nos preguntamos ¿Cómo transmitir el pasado reciente argentino a las jóvenes generaciones? ¿Cómo transmitir la herencia en un relato que invite al diálogo y la polémica?
De las reflexiones producto de los intercambios en nuestro trabajo cotidiano decidimos llevar a cabo, en el año 2021, la experiencia virtual que relatamos aquí, la que tuvo como propósito abrir un espacio para pensar/nos, narrar/nos en diálogo intergeneracional, identitario para reconocernos en una historia que nos atraviesa de modo diverso y conversar con futuros docentes sobre aquel tiempo y éste presente, en pleno contexto de pandemia COVID 19 en el que el aula se transforma en “cuadraditos en la pantalla” en los que es difícil leer la gestualidad de los cuerpos.
PALABRAS CLAVES: pasado reciente argentino- enseñanza- formación docente