bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study on Genetic Variability for Quantitative and Quality Parameters in Rice (Oryza sativa L.)
Authors: Nikhil Alahari Sai , Lal Gaibriyal M. , Reddy Inturi Naga Bala , Raju E. Bala 
Published: September 2023

Genetic variability is the prime and fundamental requirement for any crop breeding to develop superior varieties which yields more and fulfills the demanding requirements of increasing population.The current study investigates twenty genotypes of rice, including one check variety NDR-359, that were raised in the Field Experimentation Centre of the Department of Genetics and Plant Breeding, SHUATS, Prayagraj during Kharif 2022 using a Randomized Block Design with three replications.The best genotypes for grain yield per plant were chosen based on the mean performance of genotypes RNR – 1446, followed by MTU - 1121, JGL – 24423, and Rango Komal. All of the qualities under examination had significant differences, according to the analysis of variance. The characters viz., Biological yield, Grain yield per hill, Number of spikelets per panicle exhibited high Genotypic Coefficient of Variation (GCV) and Phenotypic Coefficient of Variation (PCV). For all the features under study, there were very slight variations between GCV and PCV, indicating that the environment had little to no impact on these individuals. High heritability recorded in Biological yield (95.92%), Grain yield per hill (91.89%), Panicle length (91.80%), Plant height (91.00%) and Days to 50% flowering (87.81%), whereas moderate heritability observed in Flag leaf width (47.08%). High heritability coupled with genetic advance as percent mean is recorded in Biological yield (77.10), Grain yield per hill (59.72), Panicle length (24.65) and Plant height (34.50) indicating that simple selection could be effective for improving these characters. Correlation results shown that grain yield per hill exhibited highly and significantly correlation with biological yield and Number of spikelets per panicle. The results of the Path coefficient analysis revealed that both phenotypic and genotypic levels, had positive direct effects on grain yield while compare with parameters like Biological yield, Harvest index %, Number of panicles per hill and Days to 50% flowering. Quality characters i.e., hulling (%), cooking and eating characters i.e., kernel length and breadth before and after cooking, elongation ratio was taken for 19 genotypes. As per mean performance highest maximum grain length was observed in Kasturi, DRRH2, highest elongation ratio observed in MTU - 1121 and NLR - 40024.
Attitudes and Practices of Insecticide Treated Bed Nets Usage among Rural Dwellers in Oyo State, Nigeria
Authors: Ekeleme N. C. , Ijioma C. E. , Unachukwu N. A. , Ejikem P. I. , Areh J. E. , Ogwu C. I. , Jeffery E. O. , Esangbedo I. J. , Amuta A. C. , Ojiri P. C. , Amoji N. O. , Aminu-Ayinde O. E. , Amadi E. S. , Onyeukwu N. , Abali I. O. , Airaodion A. I. 
Published: September 2023

Aim: Malaria, a life-threatening disease transmitted to humans by the bites of infected female Anopheles mosquitoes, continues to be a significant public health issue, particularly in sub-Saharan Africa. This study was aimed at understanding the attitudes and practices regarding the use of insecticide-treated bed nets (ITNs) among rural dwellers in Oyo state, Nigeria.
Methodology: The study adopted a cross-sectional design. The questionnaire was developed based on the objectives of the study. Sample size was calculated using the Fisher’s formula. The minimum sample size was 278 and was adjusted to 306 to account for non-response rate of 10%. A multi-stage cluster sampling technique was employed to select the participants.
Results: The primary understanding of the purpose of ITNs was prevention of mosquito bites (59.67%), and prevention of malaria (40.33%). However, only 74% believed that ITNs could effectively prevent malaria and just 66% considered ITNs safe for use. The practice of ITN usage was quite high, with 93% of respondents possessing ITNs in their households. ITNs were obtained predominantly through free distribution (49%) or purchase (29.67%). Use of ITNs varied among participants, with 28.67% always using it, 41% often using it, and 7% never using it. The reasons for not always using ITNs included discomfort sleeping under it (49%) and perceptions of heat (30%). An analysis of the factors affecting the usage of ITNs indicated a significant association with the age, marital status, level of education, knowledge of ITNs, and beliefs about ITN's effectiveness and safety. The usage of ITNs was particularly low among younger respondents, those who were single or widowed/divorced/separated, those with no formal education or primary education, and those who were unaware of ITNs or did not believe in their effectiveness or safety.
Conclusion: This study reveals a gap between knowledge and practice in ITN use, with significant barriers being discomfort and a lack of belief in the effectiveness of ITNs. While ownership rates are high, usage rates, especially consistent usage, is low. This was due to misconceptions, especially around the efficacy and safety of ITNs. Moreover, maintenance practices are suboptimal.
The Knowledge and Utilization of Traditional Birth Attendants by Women in a Rural Community of Ilorin, Northern Nigeria
Authors: Abdulwahab Lawal , Wuraola Salawu , Oluwanifemi Makanjuola , Ambali Ambali , Oreoluwa Alabi , Ahmed Kareem , Nwakama Chijindu , Maryam Akande , Tanimola Akande , Sumayya Al-Mansur , Yusuf Tijani , Mahmud Ahmed , Taofeek Aleem-Ghandi , John Adeyeye , Oni Nwafor , Peace Obateru , Lukman Lawal 
Published: September 2023

Background: One of the major factors contributing towards high maternal morbidity and mortality in many developing countries is the lack of access to skilled maternal healthcare services, as traditional birth attendants (TBAs) continue to serve as predominant providers of maternal healthcare in many rural communities.
Aim: This study explores the knowledge and utilization of TBAs by women in a rural community, in order to identify healthcare gaps towards the provision of needed intervention.
Study Design: This study is a descriptive cross-sectional study which was conducted in Alanamu community of Ilorin, northern Nigeria, in the year 2019.
Methodology: A well-structured interviewer based questionnaire was administered to 212 women of reproductive age-group to collect data on their knowledge and utilization of the services of TBAs. Analysis was done using Statistical Product and Service Solutions (SPSS) software version 20.
Results: One hundred and fifty three respondents (72.2%) had background knowledge of TBAs, 91 (40.8%) had visited a TBA at least once to carry out their deliveries, of which 73 (80.2%) of them had successful deliveries, 18 (19.8%) had complications during their deliveries, of which 7 (7.7%) were referred to health care facilities for expect management.
The study showed statistical significance between the level of education of respondents and their patronage of TBAs with a P-value of .04.
Conclusion: Our study showed adequate knowledge and utilization of the services of TBAs by members of the community. The use of TBAs has continued to thrive in this rural community especially among the uneducated population and has been associated with maternal complications. The integration of TBAs with standard healthcare system as well as continuous sensitization of the public on their roles and limitations would go a long way in reducing maternal morbidity and mortality associated with the use of untrained TBAs.
Development of the Q4-CNS for Reissner-Mindlin Plate Bending
Authors: Soetanto Richo Michael 
Published: September 2023

The paper was published on Matec WEB Conference Vol 147 - 2018, as seen link below: https://www.matec-conferences.org/articles/matecconf/abs/2018/06/matecconf_sibe2018_01002/matecconf_sibe2018_01002.html
Tipologi Pembentuk Kota (Street Connectivity) dan Walkability Pada Kawasan Tunjungan Surabaya
Authors: Siswanto Angelique Hillary , Sunaryo Rony Gunawan 
Published: September 2023

Kawasan Tunjungan merupakan kawasan penting di Surabaya sejak 1866 hingga sekarang. Berawal sebagai koridor penghubung antara Kota Lama dan Baru Surabaya, Tunjungan berkembang menjadi shopping-district yang terkenal dan menggerakkan roda ekonomi sekaligus sosial-budaya kota. Fenomena automobile-dependent lekat dengan masyarakat membuat orang berfokus hanya pada jalan raya, melupakan keberadaan jalan kecil yang melengkapi kawasan. Pemetaan jalan secara menyeluruh akan berdampak dalam pemerataan kawasan yang sekarang hanya terpusat di Jalan Tunjungan. Riset ini mempelajari konektivitas tipologi pembentuk kota (road mapping) dan kualitas walkability kawasan. Riset menganalisa morfologi kawasan secara sinkronis-diakronis, memetakan rute pejalan kaki-sepeda, mengidentifikasi ruang terbuka dan fasilitas publik serta menganalisa walkability kawasan melalui peta pedestrian-shed. Hasil riset dari pemetaan jalan membuka konektivitas baru yang sebelumnya tidak terlihat ketika melintasi kawasan dengan kendaraan bermotor. Riset juga menemukan variasi dan intensitas ruas jalan yang tinggi, membuat pengkajian rute jalan berdasarkan peta ped-shed menunjukkan angka permeabilitas kawasan (walkability) yang baik yaitu 0,67 dari 1,00. Namun angka ini tidak didukung dengan persentase dedicated pedestrian pathway yang baik, baru 45% jalan di kawasan nyaman digunakan. Pengolahan pedestrian yang baik (revitalisasi trotoar) akan menunjang aktivitas di kawasan dengan berjalan kaki ataupun bersepeda yang dapat mengurangi automobile dependency.
Reproductive Factors and Endometrial Cancer Risk Among Women
Authors: Katagiri Ryoko , Iwasaki Motoki , Abe Sarah Krull , Islam Md. Rashedul , Rahman Md. Shafiur , Saito Eiko , Merritt Melissa A. , Choi Ji-Yeob , Shin Aesun , Sawada Norie , Tamakoshi Akiko , Koh Woon-Puay , Sakata Ritsu , Tsuji Ichiro , Kim Jeongseon , Nagata Chisato , Park Sue K. , Kweon Sun-Seog , Shu Xiao-Ou , Gao Yu-Tang , Tsugane Shoichiro , Kimura Takashi , Yuan Jian-Min , Kanemura Seiki , Lu Yukai , Sugawara Yumi , Wada Keiko , Shin Min-Ho , Ahsan Habibul , Boffetta Paolo , Chia Kee Seng , Matsuo Keitaro , Qiao You-Lin , Rothman Nathaniel , Zheng Wei , Inoue Manami , Kang Daehee 
Published: September 2023

ImportanceDespite evidence of an association between reproductive factors and endometrial cancer risk, prospective studies have been conducted mainly in non-Asian countries.ObjectiveTo assess the association between reproductive factors, such as number of deliveries, age at menarche, or menopause, and endometrial cancer risk.Design, Setting, and ParticipantsThis cohort study used pooled individual data from 13 prospective cohort studies conducted between 1963 and 2014 in the Asia Cohort Consortium. Participants were Asian women. Data analysis was conducted from September 2019 to April 2023.ExposuresReproductive factors were assessed using a questionnaire in each cohort.Main Outcomes and MeasuresThe main outcome was time to incidence of endometrial cancer. A Cox proportional hazards model was used to calculate hazard ratios (HRs) and 95% CIs.ResultsA total of 1005 endometrial cancer cases were detected among 332 625 women (mean [SD] age, 54.3 [10.4] years) during a mean (SD) of 16.5 (6.4) years of follow-up. Increasing number of deliveries was associated with a decreased endometrial cancer risk in a dose-response manner (≥5 deliveries vs nulliparous [reference]: HR, 0.37; 95% CI, 0.26-0.53; P for trend &amp;lt; .001). Compared with menarche at younger than 13 years, menarche at 17 years or older had an HR of 0.64 (95% CI, 0.48-0.86; P for trend &amp;lt; .001). Late menopause (age ≥55 years) showed an HR of 2.84 (95% CI, 1.78-4.55; P for trend &amp;lt; .001) compared with the youngest age category for menopause (&amp;lt;45 years). Age at first delivery, hormone therapy, and breastfeeding were not associated with endometrial cancer risk.Conclusions and RelevanceThis large pooled study of individual participant data found that late menarche, early menopause, and a higher number of deliveries were significantly associated with a lower risk of endometrial cancer. These convincing results from Asian prospective studies add to the growing body of evidence for the association between reproductive factors and endometrial cancer.
Vaccines and the Risk of Hospitalization for Multiple Sclerosis Flare-Ups
Authors: Grimaldi Lamiae , Papeix Caroline , Hamon Yann , Buchard Albert , Moride Yola , Benichou Jacques , Duchemin Tom , Abenhaim Lucien 
Published: September 2023

ImportanceScientific literature is sparse about the association of vaccination with the onset of multiple sclerosis (MS) flare-ups. Immunization by vaccines of the entire population is crucially important for public health.ObjectiveTo evaluate the risk of hospitalization for severe MS flare-ups after vaccination in patients with MS.Design, Setting, ParticipantsThis cohort study included patients diagnosed with MS between January 1, 2007, and December 31, 2017, who were included in the System of National Health Databases, a national health claims database in France. In a nested case-crossover analysis, cases were defined by vaccine exposure prior to the onset of hospitalization due to an MS flare-up, and flare-up rates were compared with those that occurred prior to vaccine exposure in up to 4 control time windows immediately preceding the at-risk time window (ie, the MS flare-up) for each patient. Data were analyzed from January 2022 to December 2022.ExposureReceipt of at least 1 vaccination, including the diphtheria, tetanus, poliomyelitis, pertussis, or Haemophilus influenzae (DTPPHi) vaccine, influenza vaccine, and pneumococcal vaccine, during follow-up.Main Outcomes and MeasuresThe primary outcome was the risk of hospitalization for an MS flare-up after receipt of a vaccine. Adjusted odds ratios (AORs) and 95% CIs were derived using conditional logistic regression to measure the risk of hospitalization for an MS flare-up associated with vaccination.ResultsA total of 106 523 patients constituted the MS cohort (mean [SD] age, 43.9 [13.8] years; 76 471 females [71.8%]; 33 864 patients [31.8%] had incident MS and 72 659 patients [68.2%] had prevalent MS) and were followed up for a mean (SD) of 8.8 (3.1) years. Of these patients, 35 265 (33.1%) were hospitalized for MS flare-ups during the follow-up period for a total of 54 036 MS-related hospitalizations. The AORs of hospitalization for an MS flare-up and vaccine exposure in the 60 days prior to the flare-up were 1.00 (95% CI, 0.92-1.09) for all vaccines, 0.95 (95% CI, 0.82-1.11) for the DTPPHi, 0.98 (95% CI, 0.88-1.09) for the influenza vaccine, and 1.20 (95% CI, 0.94-1.55) for the pneumococcal vaccine.Conclusions and RelevanceA nationwide study of the French population found no association between vaccination and the risk of hospitalization due to MS flare-ups. However, considering the number of vaccine subtypes available, further studies are needed to confirm these results.
A Self‐Sustaining Hydrogels with Autonomous Supply of Nutrients and Bioactive Domains for 3D Cell Culture
Authors: Zargarzadeh Mehrzad , Gomes Maria C. , Patrício Sónia G. , Custódio Catarina A. , Mano João F. 
Published: September 2023

AbstractPhoto‐crosslinkable platelet lysate (PL)‐based hydrogels have been proven to support human‐derived cell cultures owing to their high content of bioactive molecules, such as cytokines and growth factors. As a unique self‐maintained and biocompatible 3D scaffold, the recently reported self‐feeding hydrogels with enzyme‐empowered degradation capacity have shown high biological performance in vitro and in vivo. To take advantage of all features of both PL and self‐feeding hydrogels, here UV responsive laminaran‐methacrylate (LamMA) and PL‐methacrylate (PLMA) derivatives plus glucoamylase (GA), which significantly improve the overall features of a 3D system, is coupled. This self‐sustaining hybrid hydrogel emerges as a unique scaffold due to the sustained delivery of glucose produced via enzymatic degradation of laminaran while granting the release of growth factors through the presence of PL. This biomaterial is applied to fabricate high‐throughput freestanding microgels with controlled geometric shapes. Furthermore, this multicomponent hybrid hydrogel is successfully implemented as the first reported glucose supplier bioink to manufacture intricate and precisely defined cell‐laden structures using a support matrix. Finally, such hydrogels are utilized as a proof of concept to serve as 3D in vitro cancer models, with the aim of recapitulating the tumor microenvironment.
A Bioengineering‐Regenerative Medicine Approach for Ocular Surface Reconstruction Using a Functionalized Native Cornea‐Derived Bio‐Scaffold
Authors: Park Mijeong , Richardson Alex , Delic Naomi , Nguyen Kim , Biazik Joanna , Zhang Richard , Sprogyte Lina , Nureen Lamia , Lees Justin , Fajardo Angelica , Kunicki Ursula , Watson Stephanie L. , Males John , Girolamo Nick Di 
Published: September 2023

AbstractLimbal stem cell deficiency (LSCD) is characterized by the loss of limbal epithelial stem cells (LESCs) which compromises corneal transparency, leading to blindness. It cannot be treated with pharmacological or corneal transplantation interventions, instead a specialized stem cell (SC) therapy is needed to restore eye health and sight. Herein, a native cornea‐derived biomaterial, a by‐product of a laser refractive surgical procedure called small incision lenticule extraction is identified as a new cell delivery matrix. Culture conditions are optimized to facilitate LESC attachment, expansion and stratification, and their identity is immunophenotyped. Using electron microscopy, bio‐constructs display stratification, similar to the architectural and cellular organization of a native mammalian cornea with formation of a basement membrane and an orderly array of collagen fibrils. Neuronal growth and depleted CD45+/CD14+ leukocytes on lenticules are also shown, suggesting that in transplantation experiments, they will re‐innervate and not trigger a host‐mediated immune response. Finally, human lenticules are geometrically customized to successfully fit them over a LSCD murine cornea ex vivo, during which they maintain curvature. The authors are poised to conduced similar studies in live mice using these and other carriers currently used in the clinic to compare SC therapy outcomes.
Photoinduced Contact Evolution and Junction Rearrangement in Two‐Dimensional van der Waals Heterostructure
Authors: Cen Yingqian , Tu Yudi , Zhu Jingting , Hu Yutao , Hao Qiaoyan , Zhang Wenjing 
Published: September 2023

AbstractDevices based on 2DMs van der Waals (vdW) heterostructures always compose of multiple contacts. Due to the instability of nanoscale 2DMs and interfaces, these contacts can be affected by the operation‐induced photo or thermal effect. They can trigger the evolution of junctions and rearrange the junctions across a device, which are detrimental for applications. Herein, vdW heterostructure of indium selenide (InSe) and black phosphorus (BP) on Au electrodes are investigated to reveal the contact evolution and its relation to device performance. During operation, light irradiation changes the I–V characteristics from symmetry to strong rectification. Photocurrent mapping and Kelvin‐probe force microscopy (KPFM) reveal triple junctions in this heterostructure, i.e., Au‐InSe junction, InSe homojunction, and InSe‐BP heterojunction. The variation of I–V characteristics of vdW heterostructure is ascribed to the evolution of Au‐InSe junction from quasi‐ohmic junction with a near‐zero work function difference (Δφ) to a strong Schottky junction (Δφ = ≈0.27 eV). The stabilized device demonstrates distinguished time‐domain response at individual junctions and overall device, indicating the evolution of contacts and the consequent opposite junction directions degrade the overall device performance. This research emphasizes the importance of dealing with heterogeneous contacts and junction directions in designing vdW heterostructure photodetectors.
A Zwitterionic Hydrogel with Anti‐Oxidative and Anti‐Inflammatory Properties for the Prevention of Peritoneal Adhesion by Inhibiting Mesothelial‐Mesenchymal Transition
Authors: Yu Qingyu , Sun Hong , Zhang Linhua , Jiang Lijie , Liang Lei , Yu Chaojie , Dong Xiaoru , Guo Bingyan , Qiu Yuwei , Li Jingwu , Zhang Hong , Yao Fanglian , Zhu Dunwan , Li Junjie 
Published: September 2023

AbstractPostoperative peritoneal adhesion is a serious clinical complication. Various hydrogel barriers have been developed to prevent peritoneal adhesion. However, it remains a challenge to design a hydrogel with desirable physicochemical properties and bioactivities. In this study, a zwitterionic polysaccharide‐based multifunctional hydrogel is developed using epigallocatechin‐3‐gallate (EGCG) to prevent postoperative abdominal adhesion. This hydrogel is simple to use and has desirable properties, such as excellent injectability, self‐healing, and non‐swelling properties. The hydrogel also has ultralow fouling capabilities, such as superior bactericidal performance, cell and protein adhesion, and low immunogenicity resistance. Moreover, the hydrogel exhibits good antioxidant activity, which is attributed to the integration of EGCG. Furthermore, the detailed mechanism from in vivo and in vitro experimental studies illustrates that hydrogel compositions can synergistically prevent adhesion formation through multiple pathways, including anti‐inflammatory and antioxidant capabilities and inhibition effects on the mesothelial‐mesenchymal transition (MMT) process induced by transforming growth factor (TGF‐β). In summary, this zwitterionic multifunctional hydrogel has great potential to prevent postoperative adhesion formation in the clinical setting.
Stabilizing Precursor Solution and Controlling Crystallization Kinetics Simultaneously for High‐Performance Perovskite Solar Cells
Authors: Wu Nan , Yang Tinghuan , Wang Zhichao , Wu Yin , Wang Yajie , Ma Chuang , Li Haojin , Du Yachao , Zhao Di , Wang Shuang , Liu Pengchi , Huang Wenliang , Ren Xiaodong , Liu Shengzhong (Frank) , Zhao Kui 
Published: September 2023

AbstractThe efficiency of metal halide perovskite solar cells (PSCs) has skyrocketed; however, defects created by aging precursor solutions and during crystallization pose a significant barrier to the reproducibility and efficiency of solar cells. In this work, fluoro‐N,N,N″,N″‐tetramethylformamidinium hexafluorophosphate (F‐(CH3)4CN2PF6, abbreviated as TFFH) is introduced to stabilize precursor solution and improve crystallization dynamics simultaneously for high‐performance formamidinium lead iodide (FAPbI3)‐based perovskite indoor photovoltaics. The TFFH stabilizes the precursor solution by inhibiting oxidation of I− and reducing newly generated I0 to I−, and passivates undercoordinated Pb2+ by interacting with the Pb─I framework. Time‐resolved optical diagnostics show prolonged perovskite crystallization dynamics and in situ defect passivation due to the presence of strong FA+···TFFH···Pb─I interaction. Simultaneous regulation of precursor solution and crystallization dynamics guarantee larger perovskite grain sizes, better crystal orientation, fewer defects and more efficient charge extraction in PSCs. The optimized PSCs achieve improved reproducibility and better stability and reach an efficiency of 42.43% at illumination of 1002 lux, which is the highest efficiency among all indoor photovoltaics. It is anticipated that the concurrent stabilization of solutions and regulation of crystallization dynamics will emerge as a prevalent approach for enhancing the reproducibility and efficiency of perovskite.