bluuebunny/crossref_metadata_2025_split huggingface dataset:
Animal Health, Management, and Foodborne Pathogens in Beef Feedlots
Authors: Dargatz David A. , Wagner Bruce A. , Loneragan Guy H. , Garber Lindsey P. , Hill George W. , Wineland Nora E. 
Published: February 2023

The USDA's National Animal Health Monitoring System (NAHMS) has been conducting benchmark studies of the livestock industries since the late 1980's. Through 2001 there have been studies of swine (n=3), dairy (n=2), beef cow-calf (n=2), beef feedlot (n=2), catfish (n=l), layers (n=l), sheep (n=l) and equine (n=l).
A stratified random sample of feedlot operations with at least 1000 head capacity in the 12 leading cattle feeding states1 was selected for participation in the Feedlot '99 study. Cattle from feedlots with 1000 head or more capacity in these 12 states accounted for 81.9% of fed cattle marketings for 1999. Operators of selected feedlots were contacted for a series personal interviews to collect information on health and management of cattle in their feedlot. In addition, operators were offered the opportunity to participate in activities that required the collection of water, feed or feces.
Male Reproductive Surgery
Authors: Hull Bruce L. 
Published: February 2023

Although male reproductive surgery can be very rewarding, it is overall a bad area to do surgery. To have a successful outcome there must be complete freedom of movement. The area is prone to post operative swelling and the area is contaminated, which increases the risk of post operative infection. Post operative infection leads to abscesses which lead to secondary adhesions as they heal. With these factors in mind a guarded prognosis is in order and these surgeries should only be considered on valuable animals.
Urogenital surgery requires a lot of time, not only from a surgical standpoint, but also extended time out of service post-operatively. Depending on the surgical procedure at least 30 days of sexual rest is recommended. In most cases this removes a bull from the program for an entire breeding season.
Tranquilizers should be avoided when performing urogenital surgery as many of them cause the penis and prepuce to prolapse. Prolapse increases edema to the injured part and may lead to secondary trauma. Therefore, if tranquilization is necessary it should be done lightly and with caution.
Responses of On-site Slaughterhouse Screening Tests After Administration of Ceftiofur
Authors: Robb Edward J. , Brown Scott A. , Payne Michael 
Published: February 2023

Responses of three on-site slaughterhouse screening tests, along with the FSIS - USDA Post-Screening Multiple Bioassay, are described. On-site tests include the CAST, STOP and FAST.
Kidney, liver and muscle were obtained from lactating dairy cattle after the last of five intramuscular injections of ceftiofur sodium* administered at 24-hour intervals at a dose of 2.2 mg or 1.1 ceftiofur equivalents (CE) per kg of bodyweight (0.5-1.0 mg/lb). Animals were slaughtered at 12 hours or five or 10 days.
Study of the Economic Losses Due to Bovine Paratuberculosis in Two Herds Around Tehran
Authors: Nadalian M. Gh. 
Published: February 2023

Paratuberculosis (Johne's disease) is a chronic, granulomatous enteritis and a contagious bacterial disease of the intestinal tract. Johne's disease is characterized by delayed onset and variable expression of clinical signs, including intermittent diarrhea, emaciation and sometimes submandibular edema.
Economic losses associated with Johne's disease relate to many factors, including decreased milk production and weight, increased susceptibility to other diseases, loss of genetic potential and export market and increased calving interval. Mastitis and infertility in infected cattle also are higher than in non-infected cattle but results are inconsistent. Total losses were estimated to exceed $105 billion annually for the dairy industry in the United States.4,5
Relative Risk of Liver Failure in Dairy Cows with Left Abomasal Displacement
Authors: Rehage J. , Kaske M. , Scholz H. 
Published: February 2023

Dairy cows with left abomasal displacement (LDA) are in substantial negative energy balance and mobilize considerable amounts of non-esterified fatty acids. Thus, fatty liver is a common hepatic disorder in LDA cows. Results of a previous study showed that approximately 4-5% of LDA cows referred to our clinic for surgical correction of abomasal displacement died or were sacrified due to liver coma. We found not only cows with severe fatty liver but also cows with moderate or even mild fatty liver affected by liver failure. Characteristically, cows with liver failure showed typical clinical signs of a hepatic encephalopathy (general depression, ataxia, recumbency or coma) and a low plasma amino acid ratio (Val+Leu+Ile/Phe+Tyr), low plasma cholesterol concentrations and high plasma levels of ammonia, total bilirubin and hepatic enzymes.
Thus, aim of the study was to calculate the risk of liver failure of dairy cows with LDA related to the hepatic triglyceride content.
Coenzyme Q10 for Enhancing Physical Activity and Extending the
Human Life Cycle
Authors: Bjørklund Geir , Semenova Yuliya , Gasmi Amin , Ruwan Indika Neluwa-Liyanage , Hrynovets Ihor , Lysiuk Roman , Lenchyk Larysa , Uryr Taras , Yeromina Hanna , Peana Massimiliano 
Published: February 2023

Background:
Coenzyme Q (CoQ) is an enzyme family that plays a crucial
role in maintaining the electron transport chain and antioxidant defense. CoQ10 is the
most common form of CoQ in humans. A deficiency of CoQ10 occurs naturally with aging
and may contribute to the development or progression of many diseases. Besides, certain
drugs, in particular, statins and bisphosphonates, interfere with the enzymes responsible
for CoQ10 biosynthesis and, thus, lead to CoQ10 deficiency.

Objectives:
This article aims to evaluate the cumulative studies and insights on the topic
of CoQ10 functions in human health, focusing on a potential role in maintaining physical
activity and extending the life cycle.

Results:
Although supplementation with CoQ10 offers many benefits to patients with cardiovascular
disease, it appears to add little value to patients suffering from statin-associated
muscular symptoms. This may be attributed to substantial heterogeneity in doses and
treatment regimens used.

Conclusion:
Therefore, there is a need for further studies involving a greater number of
patients to clarify the benefits of adjuvant therapy with CoQ10 in a range of health conditions
and diseases.
Predictors of Quality of Life in Women with Premature Ovarian
Insufficiency
Authors: Shabani Fatemeh , Montazeri Maryam , Mirghafourvand Mojgan 
Published: February 2023

Background::
Women with premature ovarian insufficiency (POI) have more difficulty
concerning their physical and psychological health, indicating a need to provide adequate psychosocial
and clinical support for these women to minimize the repercussion of this diagnosis on their activities
and quality of life.

Objective::
To determine the predictors of quality of life in women with premature ovarian insufficiency
(POI).

Methods::
This cross-sectional study was performed on 130 women with POI in Tabriz in 2021 by
convenience sampling. Data were collected using the socio-demographic characteristics questionnaire,
Spielberger state-trait anxiety inventory (STAI), Beck depression scale (BDI), female sexual function
index (FSFI), and the World Health Organization quality of life questionnaire (WHOQOL). The adjusted
general linear model was used to estimate the impact and determine the relationship between
independent variables (socio-demographic characteristics, anxiety, depression, and sexual function)
and dependent variables (quality of life and its domains).

Results::
The mean total score of quality of life was 46.3 (SD: 18.3) out of 0 to 100. The lowest mean
score belonged to the social relations domain (35.6 (17.0)), and the highest mean score belonged to the
physical health domain (40.0 (16.0)). Sexual function was one of the predictors of overall quality of
life score, and all its domains except environmental health. Depression was one of the predictors of
psychological health. Education was also a predictor of psychological and environmental health.

Conclusion::
Sexual function and mental health are directly related to the quality of life of women
with POI.
Effect of Natural Plant Products on Alzheimer’s Disease
Authors: Varshney Himanshi , Siddique Yasir Hasan 
Published: February 2023

Background::
Plants and their extracts like ginger, garlic, Curcuma, Salvia, and Ginkgo are
best known for their anti-oxidative and anti-inflammatory responses. These plants have shown their
anti-Alzheimer’s properties in various in vivo and in vitro studies. Their diverse phytochemicals play a
protective role against amyloid-beta-induced neurotoxicity and improve cognitive and learning impairments.
These plants have a wide range of bioactive compounds, including alkaloids, flavonoids,
phenols, glycosides, terpenoids, coumarins, and saponins. These chemicals scavenge the free radicals,
lower the amyloid burden, improve memory dysfunction, and inhibit acetylcholinesterase activity.
Some of the clinical trials and animal-based studies suggested the protective role of these plants and
their extract mentioned in the literature.

Methods::
The articles for this review were majorly searched from popular search engines, viz, Google
Scholar, PubMed, and Scopus.

Results::
Medicinal plants improve cognitive and memory impairments by inhibiting acetylcholinesterase
activity and scavenging free oxygen species by activating superoxide dismutase, catalase, and GSH activity.
The plant extracts reduce amyloid insult by inactivating the beta-site amyloid precursor protein cleaving
enzyme (BACE). The inactivation of Caspase 3 and 9 reduces apoptosis. Furthermore, the stimulation
of microglial cells and astrocyte reduce inflammation by lowering chemokines and interleukins.

Discussion::
The medicinal plants help to reduce AD pathogenesis by controlling different pathways
and could be used as a therapeutic agent against the symptoms.
Stereospecific Total Synthesis of Putaminoxin 1 by Ring Closing Metathesis
and Enantioselective Epoxidation
Authors: Shekhar Vanam , Sudhakar Chithaluri , Veerareddy Nagireddy 
Published: February 2023

Abstract:
The stereoselective synthesis of putaminoxin 1, a biologically active natural phototoxic lactone has been synthesized from (R)-2-Propyloxirane and Hex-5-en-1-ol. The synthesis involves Jacobsen’s hydrolytic kinetic resolution and ring-closing metathesis as the key steps.
Meeting the Shared Goals of a Student-Selected Component: Pilot Evaluation of a Collaborative Systematic Review
Authors: Bhatti Faheem , Mowforth Oliver , Butler Max , Bhatti Zainab , Rafati Fard Amir , Kuhn Isla , Davies Benjamin M 
Published: February 2023

Background
Research methodology is insufficiently featured in undergraduate medical curricula. Student-selected components are designed to offer some research opportunities but frequently fail to meet student or supervisor expectations, such as completion or publication. We hypothesized that a collaborative, educational approach to a systematic review (SR), whereby medical students worked together, may improve student experience and increase success.

Objective
This study aimed to establish whether offering a small team of students the opportunity to take part in the screening phase of SRs led by an experienced postgraduate team could enhance the learning experience of students, overcome the barriers to successful research engagement, and deliver published output.

Methods
Postgraduate researchers from the University of Cambridge led a team of 14 medical students to work on 2 neurosurgical SRs. One student was appointed as the lead for each SR. All students were provided with training on SR methodology and participated in title and abstract screening using Rayyan software. Students completed prepilot, midscreening, and postscreening questionnaires on their research background, perceptions, knowledge, confidence, and experience. Questions were scored on a Likert scale of 1 (strongly disagree) to 10 (strongly agree).

Results
Of the 14 students involved, 29% (n=4) reported that they had received sufficient training in research methodology at medical school. Positive trends in student knowledge, confidence, and experience of SR methodology were noted across the 3 questionnaire time points. Mean responses to “I am satisfied with the level of guidance I am receiving,” “I am enjoying being involved in the SR process,” and “I could not gain this understanding of research from passive learning e.g., textbook or lecture” were greater than 8.0 at all time points. Students reported “being involved in this research has made me more likely to do research in the future” (mean 8.57, SD 1.50) and that “this collaborative SR improved my research experience” (mean 8.50, SD 1.56).

Conclusions
This collaborative approach appears to be a potentially useful method of providing students with research experience; however, it requires further evaluation.
Predicting Habitual Use of Wearable Health Devices Among Middle-aged Individuals With Metabolic Syndrome Risk Factors in South Korea: Cross-sectional Study
Authors: Ha Jaeyoung , Park Jungmi , Lee Sangyi , Lee Jeong , Choi Jin-Young , Kim Junhyoung , Cho Sung-il , Jeon Gyeong-Suk 
Published: February 2023

Background
Prevention of the risk factors for metabolic syndrome (MetS) in middle-aged individuals is an important public health issue. Technology-mediated interventions, such as wearable health devices, can aid in lifestyle modification, but they require habitual use to sustain healthy behavior. However, the underlying mechanisms and predictors of habitual use of wearable health devices among middle-aged individuals remain unclear.

Objective
We investigated the predictors of habitual use of wearable health devices among middle-aged individuals with risk factors for MetS.

Methods
We proposed a combined theoretical model based on the health belief model, the Unified Technology of Acceptance and Use of Technology 2, and perceived risk. We conducted a web-based survey of 300 middle-aged individuals with MetS between September 3 and 7, 2021. We validated the model using structural equation modeling.

Results
The model explained 86.6% of the variance in the habitual use of wearable health devices. The goodness-of-fit indices revealed that the proposed model has a desirable fit with the data. Performance expectancy was the core variable explaining the habitual use of wearable devices. The direct effect of the performance expectancy on habitual use of wearable devices was greater (β=.537, P<.001) than that of intention to continue use (β=.439, P<.001), and the total effect estimate of the performance expectancy was 0.909 (P<.001), including the indirect effect (β=.372, P=.03) on habitual use of wearable devices via intention to continue use. Furthermore, performance expectancy was influenced by health motivation (β=.497, P<.001), effort expectancy (β=.558, P<.001), and risk perception (β=.137, P=.02). Perceived vulnerability (β=.562, P<.001) and perceived severity (β=.243, P=.008) contributed to health motivation.

Conclusions
The results suggest the importance of the users’ performance expectations for wearable health devices for the intention of continued use for self-health management and habituation. Based on our results, developers and health care practitioners should find better ways to meet the performance expectations of middle-aged individuals with MetS risk factors. They also should generate device use easier and find a way to encourage users’ health motivation, thereby reducing users’ effort expectancy and resulting in a reasonable performance expectancy of the wearable health device, to induce users’ habitual use behaviors.
Impact of the COVID-19 Pandemic on Clinical Findings in Medical Imaging Exams in a Nationwide Israeli Health Organization: Observational Study
Authors: Ozery-Flato Michal , Ein-Dor Liat , Pinchasov Ora , Dabush Kasa Miel , Hexter Efrat , Chodick Gabriel , Rosen-Zvi Michal , Guindy Michal 
Published: February 2023

Background
The outbreak of the COVID-19 pandemic had a major effect on the consumption of health care services. Changes in the use of routine diagnostic exams, increased incidences of postacute COVID-19 syndrome (PCS), and other pandemic-related factors may have influenced detected clinical conditions.

Objective
This study aimed to analyze the impact of COVID-19 on the use of outpatient medical imaging services and clinical findings therein, specifically focusing on the time period after the launch of the Israeli COVID-19 vaccination campaign. In addition, the study tested whether the observed gains in abnormal findings may be linked to PCS or COVID-19 vaccination.

Methods
Our data set included 572,480 ambulatory medical imaging patients in a national health organization from January 1, 2019, to August 31, 2021. We compared different measures of medical imaging utilization and clinical findings therein before and after the surge of the pandemic to identify significant changes. We also inspected the changes in the rate of abnormal findings during the pandemic after adjusting for changes in medical imaging utilization. Finally, for imaging classes that showed increased rates of abnormal findings, we measured the causal associations between SARS-CoV-2 infection, COVID-19–related hospitalization (indicative of COVID-19 complications), and COVID-19 vaccination and future risk for abnormal findings. To adjust for a multitude of confounding factors, we used causal inference methodologies.

Results
After the initial drop in the utilization of routine medical imaging due to the first COVID-19 wave, the number of these exams has increased but with lower proportions of older patients, patients with comorbidities, women, and vaccine-hesitant patients. Furthermore, we observed significant gains in the rate of abnormal findings, specifically in musculoskeletal magnetic resonance (MR-MSK) and brain computed tomography (CT-brain) exams. These results also persisted after adjusting for the changes in medical imaging utilization. Demonstrated causal associations included the following: SARS-CoV-2 infection increasing the risk for an abnormal finding in a CT-brain exam (odds ratio [OR] 1.4, 95% CI 1.1-1.7) and COVID-19–related hospitalization increasing the risk for abnormal findings in an MR-MSK exam (OR 3.1, 95% CI 1.9-5.3).

Conclusions
COVID-19 impacted the use of ambulatory imaging exams, with greater avoidance among patients at higher risk for COVID-19 complications: older patients, patients with comorbidities, and nonvaccinated patients. Causal analysis results imply that PCS may have contributed to the observed gains in abnormal findings in MR-MSK and CT-brain exams.
Evaluasi Kesiapan Penerapan Standar Akuntansi Keuangan Entitas Mikro Kecil Dan Menengah (Sak Emkm) Pad A Usaha Mikro Kecil Dan Menengah (UMKM) (Studi Pada UMKM Di Kota Samarinda)
Authors: Seftiany Tuti , Wijayana Singgih 
Published: February 2023

Penelitian ini mendeskripsikan hasil evaluasi yang dilakukan pada usaha kecil di Kota Samarinda, khususnya pada entitas mikro terkait sejauh mana entitas-entitas tersebut siap untuk menerapkan Standar Akuntansi Keuangan untuk menunjang kebtuhan dan keselarasan pelaporan keuangan dalam upaya keberlanjutan entitas UMKM tersebut. Penelitian ini menggunakan pendekatan kuantitatif. Pengumpulan data dilakukan dengan metode penyebaran kuesioner kepada 236 sampel dari kelompok usaha kecil yang ada di Kota Samarinda, Provinsi Kalimantan Timur. Data terkait sampel dari penelitian diperoleh dari DISPERNDAGKOP Provinsi Kalimantan Timur yang berada di Kota Samarinda. Penilitian ini menggunakan empat indikator untuk menilai kesiapan UMKM yaitu pengetahuan, pemahaman, asusmsi biaya dan manfaat, dan sumber daya manusia.Hasil dari penelitian ini menunjukan bahwa entitas secara signfikan belum siap untuk mengimplementasikan Standar Akuntansi Keuangan Entitas Mikro Kecil dan Menengah (SAK EMKM). Entitas yang sudah membuat laporan keuangan masih banyak yang menggunakan jasa dari Kantor Jasa Akuntan (KJA) walaupun sudah memiliki sumber daya yang menangani bagian keuanggan entitas. Penggunaan laporan keuangan tersebut juga masih ditujukan untuk pengambilan keputusan dan kebutuhan perpajakan. Studi ini memberikan gambaran bahwa, dibutuhkannya sinergi dari pihak pemerintah dan sisi akademisi untuk memberikan edukasi tidak hanya kepada pelaku UMKM. Namun, juga kepada calon sumber daya manusia yang akan bekerja di bidang akuntansi untuk memiliki kesadaran terhadap Standar Akuntansi yang berlaku, khususnya di Kota Samarinda.
arbitraje comercial internacional como forma de resolución de controversias en España
Authors: Ortega Giménez Alfonso 
Published: February 2023

El arbitraje como forma de resolución de controversias, se encuentra fundamentado en la voluntad libre de las partes. Esta institución juridica ha tenido un crecimiento importante en los últimos años y su uso se ha convertido en regular, pues permite a las partes que deciden someterse, solucionar los conflictos que pudieran derivarse de su relación contractual de manera ágil y eficaz. El presente artículo, dara un panorama sobre el arbitraje, su concepto, vias procedimentales y los tipos de este, que se encuentran, de acuerdo al procedimiento arbitral en España, analizando sus ventajas, ya que se introducen consejos sobre cómo redactar una cláusula arbitral, concluyendo con una reflexión acerca de por qué el arbitraje en España no tiene tanto éxito.
Telehealth and Type 1 Diabetes Care During COVID-19: Perceptions From Youth of Color, Caregivers, and Health Care Providers
Authors: Thomas Courtney , Ramirez Alejandra Perez , Alderfer Melissa A. , Patton Susana R. , Carakushansky Mauri , Enlow Paul T. 
Published: February 2023

ObjectiveAt the outset of the coronavirus disease 2019 (COVID-19) pandemic, health care systems rapidly implemented telehealth services to maintain continuity of type 1 diabetes care. Youth of color are more likely to have suboptimal glycemic control and may benefit most from efforts to ensure continuity of care. However, research examining the perspectives of families of youth of color regarding telehealth for pediatric type 1 diabetes care is limited. We gathered perspectives from youth of color, their caregivers, and health care providers (HCPs) on telehealth for type 1 diabetes care during COVID-19.MethodsFifty participants (22 caregivers, 19 youth, and nine HCPs) completed semi-structured interviews conducted in English (n = 44) or Spanish (n = 6). Transcripts containing mentions of telehealth (n = 33) were included for qualitative analysis to extract themes pertaining to perceptions of type 1 diabetes care and telehealth use during COVID-19.ResultsThemes related to perceptions, feasibility, and quality of telehealth diabetes care were obtained. Most families had positive perceptions of telehealth. Families and HCPs described logistical and technical challenges and noted the potential for disparities in telehealth access and use. Furthermore, caregivers and HCPs felt that the lack of in-person interaction and limited access to clinical data affected the quality of care.ConclusionFamilies of youth of color with type 1 diabetes mostly had positive perceptions of telehealth but also identified issues with feasibility and quality of care. Our findings highlight a need for interventions promoting equal access to telehealth and quality care for all youth with type 1 diabetes to minimize disruptions in care.