bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk and UCON-based Access Control Model for Healthcare Big Data
Authors: Jiang Rong , Chen Xue , Yu Yimin , Zhang Ying , Ding Weiping 
Published: May 2023

Abstract

The rapid development of healthcare big data has brought certain convenience to medical research and health management, but privacy protection of healthcare big data is an issue that must be considered in the process of data application. Access control is one of the methods for privacy protection, but traditional access control models cannot adapt to the dynamic, continuous, and real-time characteristics of healthcare big data scenarios. In this paper, we propose an access control model based on risk quantification and usage control (RQ-UCON). The model adds a risk quantification module to the traditional UCON model to achieve privacy protection of medical data. This module classifies risks into direct and indirect risks and quantifies them based on the physician's visit history. The model stores the quantified risk values as subject attributes. The RQ-UCON model uses an improved Exponentially Weighted Moving Average (EWMA) and penalty factors to predict risk value and to update the risk values of the subject attributes in real-time. The RQ-UCON model uses agglomerative hierarchical clustering to cluster the risk values of physicians within the department, resulting in risk intervals for each physician's operational behavior. Each risk interval is stored as a condition in the RQ-UCON model. Finally, according to the model whether the subject attributes meet the model conditions to determine whether the subject has the corresponding access rights, and according to the risk interval to grant the subject the corresponding access rights. Through the final experiment, it can be seen that the access control model proposed in this paper has a certain control on the excessive access behavior of doctors and has a certain limitation on the privacy leakage of healthcare big data.
Bone Metabolism Markers in the Serum of Patients With Thoracic and Lumbar Injuries
Authors: Shulga Aleksey E. , Ostrovskij Vladimir V. 
Published: May 2023

Abstract
We analyzed the serum enzyme immunoassay findings of 100 patients varied in gender and age with consequences of thoracic and lumbar spine injuries to evaluate concentrations of systemic bone metabolism markers in fractures of thoracic and lumbar vertebrae, and revealed a sensitive and specific laboratory criterion for predicting the rate of resorption-plastic processes in bone regenerate.
An amplicon-based approach for fast and scalable genome sequencing of lumpy skin disease virus on benchtop next-generation sequencers
Authors: Bhoyar Rahul C. , Jolly Bani , Vignesh Harie , Bhatt Lenin , Senthivel Vigneshwar , Israni Ravi , Scaria Vinod , Sivasubbu Sridhar 
Published: May 2023

Abstract
Lumpy Skin Disease (LSD) is a viral disease predominantly affecting cattle and caused by a poxvirus belonging to the capripoxvirus genus. LSD is characterized by extensive cutaneous lesions, with severe consequent morbidity and sometimes mortality of the affected animal. Timely diagnosis and control of the spread of infections through measures including vaccination are therefore of great importance in preventing social and economic consequences of the disease. Genomic studies from outbreaks in the past have provided unique insights including the identification of recombinant variants in recent years. Genome sequencing and genomic surveillance of the disease therefore could provide useful insights into the evolution and epidemiology of the virus and could potentially also contribute to the development of diagnostic tools. Previous approaches for genome sequencing of the virus used a variety of approaches including amplicon-based sequencing as well as metagenomic approaches, which are tedious, time-consuming as well as costly. The wide availability of benchtop next-generation sequencing equipment and the application of sequencing-based approaches to enable genomic epidemiology of SARS-CoV-2 at scale, motivated us to create an amplicon-based approach based on the Illumina COVIDSeq assay1. for fast, scalable and cost-effective sequencing of the Lumpy Skin Disease Virus. This protocol is a modification of the previously published COVIDSeq assay 1 and can be adapted to any Illumina sequencing platform as an accelerated and scalable system for quick detection as well as genomic surveillance of LSD.
For complete details on the use and execution of this protocol, please refer to Bhatt et al. (2023).2
WITHDRAWN: A Hybrid Deep Learning Framework to Predict Alzheimer’s Disease Progression Using Generative Adversarial Networks and Deep Convolutional Neural Networks
Authors: SinhaRoy Rajarshi , Sen Anupam 
Published: May 2023

Abstract
A major research subject in recent times is Alzheimer’s disease (AD) due to the growth and considerable societal impacts on health. So, the detection of AD is essential for medication care. Early detection of Alzheimer’s disease (AD) is critical for effective treatment and monitoring the time period between normal aging’s unavoidable cognitive loss & dementia’s more catastrophic degradation is common practice. The deep learning method for early diagnosis and automated categorization of Alzheimer’s disease (AD) has suddenly gained a lot of attention since rapid advancement in the field of GANs approaches has now been used in the clinical research sector. Many recent studies using brain MRI images and convolutional neural networks (CNN) to identify Alzheimer’s disease have yielded promising results. Instead of adequately engaging with the lack of Real data, many research papers have focused on prediction. The main purpose of this paper is to do this by generating synthetic MRI images using a series of DCGANs. This paper demonstrates the effectiveness of this concept by cascading DCGANs that imitate different stages of Alzheimer’s disease & utilizing SRGANs to enhance the resolution of MRI scans. The purpose of this research is to come forward and tell if an individual might just get Alzheimer’s disease. CNN, DCGANs, and SRGANs are used in this paper to present a Deep Learning-based approach that improves classification and prediction accuracy to 99.7% and also handles the lack of data and the resolution of data.
TRAVEL PATTERN WISATA RELIGI DI JAWA TENGAH
Authors: Hakim Lukmanul , Muhajarah Kurnia 
Published: May 2023

Abstrak: Penelitian ini bertujuan untuk perencanaan Travel Pattern wisata religi di Jawa Tengah, Indonesia. Wisata religi menjadi daya tarik utama bagi para wisatawan karena memberikan pengalaman spiritual dan kegiatan yang berbeda. Metode yang digunakan adalah library research (penelitian kepustakaan), dan bersifat kualitatif, deskriptif analisis. Hasil Penelitian travel Pattern wisata religi di Jawa Tengah diperoleh kesimpulan yaitu: perlu perencanaan paket wisata yang menarik, pembuatan pola dan model perjalanan yang murah dan efisien, akomodasi, dan aksesibilitas yang baik. Pembuatan pola perjalanan wisata religi khususnya wisata ziarah harus memperkenalkan paket wisata atau destinasi wisata yang menarik selain yang sering dikunjungi oleh para peziarah. Hal tersebut perlu diperhatikan masalah kemudahan informasi yang harus diupdate menggunakan sistem digitalisasi dan aplikasi yang support saat ini untuk memperoleh informasi terkait wisata religi di Jawa Tengah.
Kata Kunci: Travel Pattern; Wisata Religi; Wisata

Abstract: This study aims to plan a religious tourism Travel Pattern in Central Java, Indonesia. Religious tourism is the main attraction for tourists because it provides spiritual experiences and different activities. The method used is library research, and is qualitative, descriptive analysis. The results of the research on religious tourism travel patterns in Central Java obtained conclusions, namely: it is necessary to plan attractive tour packages, make cheap and efficient travel patterns and models, accommodation, and good accessibility. Making religious tourism travel patterns, especially pilgrimage tourism, must introduce tour packages or tourist destinations that are interesting other than those frequented by pilgrims. It should be noted the issue of ease of information that must be updated using the current digitization system and application support to obtain information related to religious tourism in Central Java.
Keywords: Travel Pattern; Religious Tourism; Tourism
PENGARUH ATTRACTION, ACCESSIBILITY, AMENITY, ANCILLARY TERHADAP MINAT KUNJUNG ULANG PEZIARAH DI MAKAM SYEKH ABU BAKAR JEPARA
Authors: Islam Putri Izzatul , Savitri Fania Mutiara 
Published: May 2023

Abstrak: Penelitian ini bertujuan untuk menganalisis pengaruh Atraction, Accessibility, Amenity dan Ancillary terhadap minat kunjung ulang peziarah di makam Syekh Abu Bakar Jepara. Penelitian ini berlokasi di makam Syekh Abu Bakar desa Ujungbatu Pulau Panjang Jepara. Pendekatan dalam penelitian ini adalah pendekatan kuantitatif, metode survey dengan menyebar 100 kuesioner kepada 100 orang responden. Peniliti menggunakan teknik pengumpulan data menggunakan formula Lemeshow untuk populasi yang tidak diketahui melalui kuesioner. Untuk uji statistik dan pengolahan data dilakukan dengan menggunakan partial least square (AmartPLS 3.0). Penelitian menunjukkan bahwa Attraction berpengaruh terhadap minat kunjung ulang peziarah pada makam Syekh Abu Bakar Jepara, Accessibility tidak berpengaruh terhadap minat kunjung ulang peziarah pada makam Syekh Abu Bakar Jepara, Amenity tidak berpengaruh terhadap minat kunjung ulang peziarah pada makam Syekh Abu Bakar Jepara, Ancillary berpengaruh terhadap minat kunjung ulang peziarah pada makam Syekh Abu Bakar Jepara.
Kata Kunci: Attraction; Accessibility; Amenity; Ancillary; Minat Kunjung Ulang

Abstract: This study aims to analyze the effect of Attraction, Accessibility, Amenity and Ancillary on pilgrims' intention to revisit the tomb of Syekh Abu Bakar Jepara. This research is located at the tomb of Sheikh Abu Bakar, Ujung batu Village, Panjang Island, Jepara. The approach in this study is a quantitative approach, a survey method by distributing 100 questionnaires to 100 respondents. Researchers used data collection techniques using the Lemeshow formula for unknown populations through questionnaires. Statistical tests and data processing were carried out using partial least squares (AmartPLS 3.0). Research shows that Attraction has an effect on pilgrims' intention to return to the tomb of Sheikh Abu Bakar Jepara, Accessibility has no effect on pilgrims' intention to return to Syekh Abu Bakar Jepara's tomb, Amenity has no effect on pilgrims' intention to return to Syekh Abu Bakar Jepara's tomb, Ancillary has no effect on the interest of pilgrims returning to the tomb of Sheikh Abu Bakar Jepara.
Keywords: Attraction; Accessibility; Amenity; Ancillary; Intention to Revisit
PENGARUH MOBILE BANKING, BOPO, DPK, DAN TRANSAKSI VALAS, TERHADAP FEE BASED INCOME
Authors: Rahayu Sherlita Ribkha , Lestari Murti 
Published: May 2023

ABSTRACT Banking services are activities carried out by banks to support their main activities. Banking services generate income in the form of fees or known as fee base income. The rapid development of technology encourages the banking industry to innovate, especially in service products. This study aims to analyze how the influence of Operating Income Operating Expenses (BOPO), Third Party Funds (DPK), foreign exchange transactions, and mobile banking (M-banking) on fee based income. The sampling technique used is purposive sampling technique. The sample used is the National Private Bank with the largest asset value in Indonesia for the period 2006-2020. The data analysis used in this study is panel data regression (pooled). This study uses the Fixed effect Regression Model. The results of the study show that foreign exchange transactions have a significant positive effect on fee-based income. Meanwhile, BOPO, DPK, and M-banking have no significant effect on fee-based income. Keywords : BOPO, DPK, foreign exchange transaction, fee based income ABSTRAK Layanan jasa perbankan merupakan kegiatan yang dilakukan bank untuk menunjang kegiatan utamanya. Layanan jasa perbankan menghasilkan pendapatan berupa fee atau dikenal dengan fee base income. Pesatnya perkembangan teknologi mendorong industri perbankan untuk berinovasi, terutama pada produk layanan jasa. Penelitian ini bertujuan untuk menganalisis bagaimana pengaruh Beban Operasional Pendapatan Operasional (BOPO), Dana Pihak Ketiga (DPK), transaksi valas, dan Mobile banking (M-banking) terhadap fee based income. Teknik pengambilan sampel yang digunakan adalah teknik purposive sampling. Sampel yang digunakan adalah Bank Swasta Nasional dengan nilai asset terbesar di Indonesia periode 2006-2020. Analisis data yang digunakan dalam penelitian ini adalah regresi data panel (pooled). Penelitian ini menggunakan Model Regresi Fixed effect. Hasil Penelitian menunjukan bahwa transaksi valas berpengaruh positif signifikan terhadap fee based income. Sedangkan BOPO, DPK, dan M-banking tidak berpengaruh signifikan terhadap fee based income. Kata Kunci : BOPO, DPK, transaksi valas, fee based income
PENERAPAN BIG DATA ANALYTICS DAN ESKALASI KEMAMPUAN AUDITOR
Authors: Edward Zevan Ricardo 
Published: May 2023

ABSTRACT The use of Big Data is predicted to be used more intensively because it will certainly benefit the auditor and the company because it can reduce costs and travel time, improve the quality of audit results, and allow auditors to use more comprehensive data. But on the other hand there are problems that arise related to audit time pressure which makes audit quality threatened. Audit time pressure has been a scourge for auditors for years, caused either because of regulations or because of the ability of the auditors themselves. With the times, these problems can be avoided, one of which is by optimizing big data. Fast and accurate data processing can help auditors in archiving data faster and even more than that big data is able to offer more things such as changing the sampling paradigm to 100% of the population. The use of a continuous auditing framework certainly also complements big data and auditors because a framework that focuses on continuous auditing can help auditors get optimal results so that audit time pressure problems can be resolved. Keywords : Auditor, Big Data, Continuous Auditing, Audit Time Pressure ABSTRAK Penggunaan Big Data diprediksi akan semakin intensif digunakan karena tentu akan menguntungkan auditor dan perusahaan karena dapat menekan biaya dan waktu perjalanan, meningkatkan kualitas hasil audit, dan memungkinkan auditor dapat menggunakan data yang lebih komprehensif. Namun disisi lain ada masalah yang muncul terkait audit time pressure yang membuat kualitas audit menjadi terancam. Audit time pressure menjadi momok bagi auditor selama bertahun-tahun yang disebabkan baik karena regulasi atau karena kemampuan auditor itu sendiri. Dengan perkembangan zaman, permasalahan tersebut bisa terhindarkan salah satunya dengan optimalisasi big data. Pengolahan data yang cepat dan akurat dapat membantu auditor dalam pengarsipan data yang lebih cepat pula bahkan lebih dari itu big data mampu menawarkan hal yang lebih seperti merubah paradigma sampling menjadi 100% populasi. Penggunaan framework continuous auditing tentu juga semakin melengkapi big data dan auditor karena framework yang menitikberatkan pada pengauditan terus menerus dapat membantu auditor mendapatkan hasil yang optimal sehingga permasalahan audit time pressure dapat terselesaikan. Kata Kunci : : Auditor, Big Data, Continuous Auditing, Audit Time Pressure
PERSEPSI MAHASISWA TERHADAP PROFESIONALISME DOSEN AKUNTANSI DI LINGKUNGAN PERGURUAN TINGGI SWASTA DI SURAKARTA
Authors: Pramesti Hernawati , Satyawati Endang 
Published: May 2023

ABSTRACT The problem to be answered is how the students' perceptions of the professionalism of accounting lecturers in private universities in Surakarta. This study uses a survey method. The population includes all university students in Surakarta. The research sample was taken using purposive sampling method and convenience sampling. Data collection through questionnaires and collected as many as 40 sheets. In this study, lecturers' professionalism was measured using 4 professionalism factors, namely skills, knowledge, attitudes, and ethics. Hypothesis analysis was carried out by proportion analysis, score analysis, and Chi-Square analysis. The results of the analysis show that the null hypothesis is accepted, namely the Student's Perception of the Professionalism of Accounting Lecturers in Private Universities in Surakarta is good. Keywords: perception, professionalism, expertise, attitude and ethics. ABSTRAK Masalah yang hendak dicari jawabannya adalah bagaimanakah persepsi mahasiswa terhadap profesionalisme dosen akuntansi di lingkungan Perguruan Tinggi swasta di Surakarta. Penelitian ini menggunakan metode survei. Populasi mencakup seluruh mahasiswa Perguruan Tinggi di Surakarta. Sampel penelitian diambil dengan menggunakan metode purposive sampling dan conveniance sampling. Pengumpulan data melalui kuesioner dan yang terkumpul sebanyak 40 lembar. Dalam penelitian ini profesionalisme dosen diukur dengan menggunakan 4 faktor profesionalisme yaitu skill, knowledge, attitute, dan ethics. Analisis hipotesis dilakukan dengan analisis proporsi, analisis skor, dan analisis Chi-Square. Hasil analisis menunjukkan bahwa, hipotesis nol diterima yaitu Persepsi Mahasiswa terhadap Profesionalisme Dosen Akuntansi di lingkungan Perguruan Tinggi Swasta di Surakarta baik. Kata kunci: persepsi, profesionalisme, keahlian, sikap dan etika
Functional constipation in patients with injuries of the musculoskeletal system
Authors: Lazareva Yu. A. , Egorov D. V. , Seliverstov P. V. 
Published: May 2023

This paper highlights the problem of functional constipation, its epidemiology, etiology, features of the clinical picture during prolonged immobilization in injured patients, and approaches to therapy. Stool retention in patients undergoing prolonged immobilization is an urgent medical problem, since it occurs in most of these patients. The paper presents a clinical example of managing a patient with an injury to the musculoskeletal system and functional constipation. Functional constipation is associated with a number of pathophysiological processes: genetic characteristics, lifestyle (lack of physical activity) and eating style characteristic of Western cultures (low intake of dietary fiber and water), intestinal movement disorders that can be caused by numerous causes (neurogenic factors , diseases of the endocrine glands, circulatory disorders in the intestinal vessels, taking certain medications), anatomical features (dolichosigma), as well as social factors (late awakening, morning rush, work in different shifts, changes in the usual living and working conditions) and psychological patient features. The possibilities of lifestyle modification in patients with injuries of the musculoskeletal system are very limited, and special attention should be paid to correcting nutrition and observing the drinking regimen. The key point in the treatment of functional constipation in such patients will be the appointment of stimulant laxatives, one of which is sodium picosulfate. At the stages of treatment and rehabilitation, the patient should be recommended measures for modifying lifestyle and nutrition, exercise therapy in accordance with his physical capabilities and clinical recommendations for the treatment of constipation.
Implementation of Accounting Standards as an effort to realize the Accountability of Sharia Microfinance Institutions
Authors: Saadah Naili 
Published: May 2023

Purpose - This study aims to analyze the presentation of the financial statements of what factors influence the presentation of the financial statements of Islamic microfinance institutions according to PSAK 101. Method - This study aims to explore the implementation of accounting standards which are the basis for the presentation of financial statements of Islamic entities, therefore field research with qualitative methods is considered the most appropriate in this study.Result - The results of this study show that in the implementation of accounting standards, sharia people's credit banks have implemented applicable accounting standards while sharia savings and loan cooperatives which are part of sharia entities have not been fully implemented, this is because there are several parts of financial statements that are not presented even though these parts are not crucial, for example zakat infaq and sodaqoh reports some sharia entities do not present because the ZIS levy has been managed by a separate institution so that the reporting is also separate, besides that there are still many human resources who do not understand sharia SAK is an obstacle that is commonly encountered in the field.Implication - Referring to the results of this research, through this research, it is hoped that it will have implications for efforts to improve the competence of financial human resources in order to better understand the applicable accounting standards.Originality - This study seeks to compare the implementation of the presentation of financial statements in several BPRS and BMT and identify weaknesses in the implementation of SAK.
Research Progress of BAP1 in Structure, Function, and Cancer
Authors: Lu Wei-Tao , Li Meng-Ru , Yang Yi-Bo , Sun Yan-Yan , Dong Chun-Ming 
Published: May 2023

Abstract:
Cancer is an important chronic non-communicable disease that endangers human health and
has become the main cause of death of residents around the world in the 21st century. At present, most
of the mature treatment methods stay at the level of cell and tissue, which is difficult to fundamentally
solve the problem of cancer. Therefore, explaining the pathogenesis of cancer at the molecular level
becomes the answer to the key problem of cancer regulation. BRCA-associated protein 1 (brca1-
associated protein 1) is a kind of ubiquitination enzyme encoded by the BAP1 gene and composed of
729 amino acids. As a carcinogenic protein, BAP1 can affect the cancer cell cycle and proliferation
capacity, mutation, and deletion. For example, depending on catalytic activity, it participates in the
regulation of intracellular function through transcription, epigenetic, and DNA damage repair. This
article mainly reviews the basic structure and function of BAP1 in cells, its role in cancer
development, and cancer-related mutants.
NIO-1, A Novel Inhibitor of OCT1, Enhances the Antitumor Action
of Radiofrequency Ablation against Hepatocellular Carcinoma
Authors: Yang Hua , Yang Yang , Zou Xiaozheng , Zhang Qian , Li Xiaoli , Zhang Chunyu , Wang Yanan , Ren Lili 
Published: May 2023

Background:
Radiofrequency ablation (RFA) is an important treatment
strategy for patients with advanced hepatocellular carcinoma (HCC). However, its
therapeutic effect is unsatisfactory and recurrence often occurs after RFA treatment. The
octamer-binding transcription factor OCT1 is a novel tumour-promoting factor and an
ideal target for HCC therapy.

Objective:
This study aimed to expand the understanding of HCC regulation by OCT1.

Methods:
The expression levels of the target genes were examined using qPCR. The
inhibitory effects of a novel inhibitor of OCT1 (NIO-1) on HCC cells and OCT1 activation
were examined using Chromatin immunoprecipitation or cell survival assays. RFA was
performed in a subcutaneous tumour model of nude mice.

Results:
Patients with high OCT1 expression in the tumour tissue had a poor prognosis
after RFA treatment (n = 81). The NIO-1 showed antitumor activity against HCC cells
and downregulated the expression of the downstream genes of OCT1 in HCC cells,
including those associated with cell proliferation (matrix metalloproteinase-3) and
epithelial-mesenchymal transition-related factors (Snail, Twist, N-cadherin, and
vimentin). In a subcutaneous murine model of HCC, NIO-1 enhanced the effect of RFA
treatment on HCC tissues (n = 8 for NIO-1 and n = 10 for NIO-1 + RFA).

Conclusion:
This study demonstrated the clinical importance of OCT1 expression in
HCC for the first time. Our findings also revealed that NIO-1 aids RFA therapy by
targeting OCT1.