bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effect of Reflection Supported Learning of Writing on Students’ Writing Attitude and Writing Achievement Goal Orientations
Authors: Deti Taddese , Ferede Tekile , Tiruneh Dagne 
Published: January 2023

Abstract
The purpose of this study is to investigate how reflection-supported learning of writing affects students' writing attitude and writing achievement goal orientations. First-year natural science students from Jimma University were the study participants. In the study a quasi-experimental research design was used. Consequently, from 25 sections in the first year of natural science, two sections were randomly selected, and a coin was flipped to assign them into control and experimental groups. In the study, a control group of 49 and an experimental group of 50 participants participated. A questionnaire was administered to both groups before and after treatment to measure writing attitudes and writing achievement goals. A one-way between groups Multivariate Analysis of Variance (MANOVA) was calculated using Statistical Package for Social Science (SPSS), version 24. The SPSS software was used also to calculate Paired samples t- test to determine the differences of mean scores within each group pre and posttreatment. There was a statistically significant difference between the experimental and control groups on the combined dependent variables, writing attitude and writing achievement goal orientations. Thus, reflection-supported learning of writing has a positive effect on students’ writing attitude and writing achievement goal orientations. Hence, EFL instructors called on to support their teaching of writing with students’ guided reflection on pieces of writing that they produce.
Overexpression of SOX4 indicates poor prognosis and promotes progression of hypopharyngeal carcinoma
Authors: Zhang Xiao-bo , Liu Hui-ting , Liu Yuan-ru , Zuo Fan , Wang Zhi-xia , Ren Qian-qian , Yao Yao , Chen Yan , Gao Qian , Gu Xing-xing , Zhang Zhen-xin 
Published: January 2023

Abstract
Objectives.
Members of the SOX family's subgroup C include SOX4, whose high expression has been linked to carcinogenesis and the development of cancer. However, it is still unclear exactly how SOX4 functions in hypopharyngeal carcinoma (HPC). Our research's objective was to discover how SOX4 affected HPC's development, migration, and prognosis.
Methods.
The expression levels of SOX4 and Ki-67 in tissues were examined by immunohistochemical staining (IHC) to analyze their relationship with prognosis in this study. Changes in SOX4 gene transcript levels and protein expression levels in HPC cancer tissues and adjacent normal tissues were assessed by quantitative real-time PCR (qRT-PCR) and Western blot. Cell biology and molecular assays, as well as in vivo nude mice cancer experiments, were used to evaluate the effects of SOX4 on the viability, proliferation, and migration of Fadu cells in vitro and in vivo.
Results.
In HPC samples, SOX4 was considerably overexpressed, and our investigation demonstrated that this overexpression was connected with differentiation (P = 0.002), clinical stage (P < 0.001), lymph node metastasis (P < 0.001), tumor size (P = 0.006) and poor survival (P = 0.012). Moreover, knockdown of SOX4 can inhibit the proliferation, reduce their migration, and promote the epithelial to mesenchymal transition (EMT) phenotype in HPC cells. SOX4 knockdown inhibited tumor growth in vivo experiments.
Conclusions.
These findings collectively show that SOX4 promotes HPC migration and progression both in vitro and in vivo, and may be a prognostic marker for HPC patients.
Evaluation of electronic patient reported outcome assessment in inpatient cancer care: a feasibility study
Authors: Salm Hanna , Hentschel Leopold , Eichler Martin , Pink Daniel , Fuhrmann Stephan , Kramer Michael , Reichardt Peter , Schuler Markus K. 
Published: January 2023

Abstract
Purpose
Patient-reported outcome (PRO) measures are increasingly important in evaluating medical care. The increased integration of technology within the healthcare systems allows for collection of PROs electronically. The objectives of this study were to (1) implement an electronic assessment of PROs in inpatient cancer care and test its feasibility for patients, as well as (2) determine the equivalence of the paper and electronic assessment.
Methods
The study is an interventional, three-arm and multicenter inpatient trial. A self-administered questionnaire based on validated PRO-measures was applied and completed at admission, one week after, and at discharge. For this analysis - focusing on feasibility of the electronic assessment - two groups will be considered: Group A (intervention arm) received a tablet version while group B (control arm) completed the questionnaire on paper. A feasibility questionnaire, that was adapted from Ashley et al. (1), was administered to group A.
Results
N = 125 patients were recruited in oncology wards. ePRO was feasible to most patients, with 84% preferring the electronic over paper-based assessment. The feasibility questionnaire contained questions that were answered on a scale ranging from ‘1’ (illustrating non achievement) to ‘5’ (illustrating achieving goal). The majority (mean 4.24, SD .99) reported no difficulties handling the electronic tool and found it relatively easy finding time for filling out the questionnaire (mean 4.15, SD 1.05). There were no significant differences between the paper and the electronic assessment regarding the PROs.
Conclusion
Results indicate that electronic PRO assessment in inpatient cancer care is feasible.
Counteracting data bias and class imbalance – towards useful and reliable retinal disease recognition system
Authors: Karanowski Konrad , Chłopowiec Adam Ryszard , Skrzypczak Tomasz , Grzesiuk Mateusz , Chłopowiec Adrian Bendykt , Tabakov Martin 
Published: January 2023

Abstract
Fundus images play a fundamental role in the early screening of eye diseases. On the other hand, as deep learning provides an accurate classification of medical images, it is natural to apply such techniques for fundus images. There are many developments in deep learning for such image data but are often burdened with the same common mistakes. Training data are biased, not diverse and hidden to the public. Algorithms classify diseases, which suitability for screening could be questioned. Therefore, in our research, we consolidate most of the available public data of fundus images (pathological and non-pathological) taking into consideration only image data relevant to the most distressing retinal diseases. Next, we apply some well-known state-of-the-art deep learning models for the classification of the consolidated image data addressing class imbalance problem occurring in the dataset and clinical usage. In a conclusion, we present our classification results for diabetic retinopathy, glaucoma, and age- related macular degeneration disease, which are urgent problem of ageing populations in developed countries.
Microbial traceability analysis of Chinese Feng-flavour Daqu to explore the influence of environmental microorganisms
Authors: Zhang Yongli , Xu Chen , Xing Gang , Yan Zongke , Chen Yaodong 
Published: January 2023

Abstract
Aims:Analysis the changes of microorganisms during Chinese Feng-flavour Daqu fermentation, and the specific contribution of different environmental factors to Daqu microorganisms.
Methods and Results: High throughput sequencing technology and SourceTracker software were used to analyze the microbial diversity of Feng-flavour Daqu before and after fermentation. 85 fungal and 105 bacterial were detected in the newly pressed Feng-flavour Daqu, while 33 fungal and 50 bacterial in the mature Daqu, and 202 fungal and 555 bacterial in the environmental samples. After fermentation, the microbial community structure of Daqu changed and decreased significantly.
Conclusions: 94.7% of fungi come from raw materials and 1.8% from outdoor ground, 60.95% of bacteria come from indoor ground, 20.44% from raw materials, and 8.98% from tools. By comparing the changes of microorganisms in Daqu before and after fermentation, the microorganisms in mature Daqu may mainly come from not only the enhanced strains but also the environment.
Significance and Impact of the Study: The source of main microorganisms in Feng-flavour Daqu and the influence of environmental factors on the quality of Daqu were clarified, which provided a basis for improving the quality of Feng-flavour Daqu.
The Effect of Polydioxanone Thread and Platelet Rich Plasma in Treating Myofascial Pelvic Pain
Authors: Kim Junam , Yi Kyu-Ho , Jeong Wooju 
Published: January 2023

Abstract
Introduction

Myofascial pelvic pain is a major component of chronic pelvic pain. Effective treatments are available to reduce pain, including myofascial tender point release. The study investigated the safety, feasibility and early outcomes of releasing myofascial tender point by polydioxanone thread and platelet rich plasma treatment in myofascial pelvic pain patients.

Methods

Twenty myofascial pelvic pain patients underwent polydioxanone thread and platelet rich plasma treatment. After autologous platelet rich plasma was injected into the pelvic muscles through vaginal access, a multi-braided polydioxanone thread was inserted into the middle and deep layers of the pelvic muscles. Pre- and post-procedural satisfaction surveys and Female Sexual Function Index scores (FSFI) were obtained. Vaginal manometry measured mobility and pressure of pelvic floor muscles. The patients were followed-up at 3 and 6 months after the procedure.

Results

At 3-months after the procedure, 65% of the patients answered positively on the improvement of symptoms and tenderness, 35% answered no difference, and none answered worsening. At this period, FSFI did not show a significant change in any of the six categories. After six months, however, there was a statistically significant improvement in all the indices except for sexual desire (p < 0.05).

Conclusions

Pelvic floor muscle targeted polydioxanone thread insertion and platelet rich plasma injection is safe and feasible, and may minimize pelvic pain without side effects such as infection or bleeding. It may potentially improve urinary control and sexual function by releasing myofascial tenderness.
Comparison of the Clinical and Prognosis Risk Factors Between Endoscopic Mucosal Dissection/Endoscopic Mucosal Resection and Radical Gastrectomy for Early-Stage Gastric Cancer.
Authors: Dao Qianze , Chen Ke , Zhu Liang , Wang Xiaoshan , Chen Mengding , Wang Jian , Wang Zhengguang 
Published: January 2023

Abstract
Aim: This study aimed to explore the efficacy and safety of endoscopic mucosal dissection/endoscopic mucosal resection (ESD/EMR), laparoscopic-assisted radical gastrectomy (LARG), and open radical gastrectomy (ORG) in early-stage gastric cancer.
Methods: A total of 417 patients with early-stage gastric cancer who were admitted in two hospitals from January 1, 2014 to July 31, 2017 were selected; the patients were divided into the ESD/EMR group (139 cases), LARG group (108 cases), and ORG group (170 cases) according to the operation methods used. The baseline data, economic cost of health, oncologic characteristics, postoperative complications, 5-year overall survival and disease-free survival, and risk factors of death were compared and analyzed.
Results: No significant difference was observed in the baseline data among the three patient groups (P>0.05). The total hospitalization days, operation time, postoperative fluid intake time, hospitalization expenses, and proportion of antibiotic use rate in the ESD/EMR group were lesser than those in other groups (P<0.05). The LARG group has a longer operation time and higher hospitalization expenses compared with the ORG group (P<0.05), but the total hospitalization days, postoperative fluid intake time, proportion of antibiotic use, and lung infection status were consistent. The ESD/EMR group had a lower incidence of incisionsite infection and postoperative abdominal distension compared with that of the surgerygroups (P<0.05). Five patients required radical surgery after undergoing ESD/EMR (all 5 had residual tissue margin cancer), while none of the patients had switched to ORG during LARG. Surgery had advantages over ESD/EMR in terms of lymph node dissection (P<0.05). No significant differences were observed in the postoperative complications such as upper gastrointestinal bleeding, perforation, liver metastasis, pancreatic metastasis, recurrence,incision hernia, and reoperation (P>0.05). The 5-year postoperative survival rates of patients in the three groups were 94.2% (ESD/EMR), 93.5% (LARG), and 94.7% (ORG), respectively, with no significant differences (P>0.05). The binary logistics multivariate analysis showed that the tumor size, invasion depth, vascular invasion, and differentiated degree were risk factors for death in patients with gastric cancer.
Conclusions: No significant difference was observed between ESD/EMR and radical surgery. However, standardized criteria for excluding metastatic lymph nodes should be established to promote ESD/EMR.
Probing densified silica glass structure by molecular oxygen and E’ point defect formation under irradiation
Authors: Ollier Nadège , Reghioua Imène , Cavani Olivier , Mobasher Mahinour , Alessi Antonino , Floch Sylvie Le , Skuja Linards 
Published: January 2023

Abstract
The aim of the paper was to learn more about the structure of densified silica, in particular about the metamict-like silica phase (density = 2.26g/cm3) by examining the radiation-induced formation of E’ point defects and interstitial molecular oxygen. The large amount of the molecular oxygen produced after 11 GGy integrated dose irradiation in the metamict-like phase is destroyed when this one is submitted to electron irradiation. It infers a particular behavior to this silica phase compared to the other densified silica where the amount of O2 is reduced compared to silica. The position and shape of the O2 emission line support the idea that the void configuration of metamict phase is close to silica. A strong correlation exists between the formation of 3-membered rings of Si-O bonds and E’-centers in the densification process between 2.20-and 2.26 density.
On the Distribution of Alexander Polynomials in Certain Families of Closed Braids
Authors: Ray Anwesh 
Published: January 2023

Abstract
We study the distribution of arithmetic invariants associated to Alexander polynomials for certain infinite families of links. The families of links we consider arise from braids on a fixed number of strings. We explore analogies with number theory and the distribution of class groups in various families of number fields, setting out new directions in arithmetic topology and arithmetic statistics.
Lignin-based epoxy composite vitrimers with light-controlled remoldability
Authors: Zheng Yong , Liu Tingting , He Haodong , Lv Zilu , Xu Jiayun , Ding Dayong , Dai Lin , Huang Zhanhua , Si Chuanling 
Published: January 2023

Abstract
Vitrimers open new possibilities in the reprocess of epoxy and other thermosets. However, direct heating is not practical on many occasions, and the waste vitrimers would cause great harm to the environment. In this work, we propose to use kraft lignin (KL) to fabricate vitrimer with reprocessability and environmental friendliness. The lignin-based epoxy vitrimer was fabricated by blending epoxy-modified KL and poly(ethylene glycol) bis(carboxymethyl) ether (PEG-DCM). The obtained lignin-based epoxy vitrimer (EML/PEG-DCM) showed good light-to-heat capability. Under the infrared radiation (808 nm, 1 W cm-2) for only 30 s, the surface temperature of EML/PEG-DCM was over ∼148 °C, and reached the maximum at ∼231 °C for 5 min. This good light-to-heat effect can activate the dynamic 3D crosslinking networks and repair the vitrimer. The energy consumption of the light-controlled remolding process is only one-thousandth of the conventional hot-press. This study not only helps to explore the natural characteristics of lignins, promoting their functional and intelligent utilization but also provides a new raw material platform for the development of green vitrimer materials.
The interplay between malaria vectors and human activity accounts for high residual malaria transmission in a Burkina Faso village with universal ITN coverage
Authors: Perugini Eleonora , Guelbeogo Wamdaogo Moussa , Guglielmo Federica , Poggi Cristiana , Gabrieli Eugenio , Ranson Hilary , Torre Alessandra della , Pombi Marco 
Published: January 2023

Abstract
Background: Mosquito and human behaviour interaction is a key determinant of the maximum level of protection against malaria that can be provided by insecticide treated nets (ITNs). Nevertheless, scant literature focuses on this interaction, overlooking a fundamental factor for efficient malaria control. This study aims to estimate malaria transmission risk in a Burkina Faso village by integrating vector biting rhythms with some key information about human habits.
Methods: Indoors/outdoors Human Landing Catches were conducted for 16 hours (16:00-08:00) during 8 nights (September 2020) in Goden village. A survey about net usage and sleeping patterns was submitted to half the households (October-December 2020). A subsample of A. gambiae s.l. collected specimens was molecularly processed for: species identification, Plasmodium detection from head-thoraxes, and L1014F pyrethroid-resistance allele genotyping. Hourly mosquito abundance was statistically assessed by GLM/GAM and the entomological inoculation rate (EIR) was corrected for the actual ITN usage retrieved from the questionnaire.
Results: Malaria transmission was mainly driven by Anopheles coluzzii (68.7%), followed by Anopheles arabiensis (26.2%). The overall sporozoite rate was 2%, and L1014F estimated frequency of 0.68 (N=1,070 out of 15,201 A. gambiae s.l. collected). No major shift in mosquito biting rhythms in response to ITN, nor differences between indoor and outdoor, were detected. Impressive high biting pressure (mean 30.3 mosquitoes/person/hour) was exerted from 20:00 to 06:00 with a peak at 4:00. Human survey revealed that nearly all inhabitants were awake before 20:00 and after 7:00 and at least 8.7% had no access to bednets. Adjusting for anthropological data, the EIR dropped from 6.7 to 1.2 infective bites/person/16h. In a scenario of full net coverage and accounting only for the human sleeping patterns, the daily malaria transmission risk not targetable by ITNs was 0.69 infective bites.
Conclusions: The high mosquito densities and the interplay between human/vector activities means that an estimated 10% of residual malaria transmission cannot be prevented by ITNs in the village. Locally-tailored studies, as the current one, are essential to explore the heterogeneity of human exposure to infective bites and, by consequence, to instruct the adoption of new vector control tools strengthening individual and community protection.
Fertility status and associated factors among the reproductive age group in Ethiopia: Mini Demographic and Health Survey 2019
Authors: Damete Dereje Derbew , Baraki Semere Gebremariam 
Published: January 2023

Abstract
Background: Fertility status is the possibility to produce offspring through reproduction following the onset of reproductive age. There are a number of environmental and biological factors that influence a person's reproductive behavior when viewed from a demographic perspective, which serve to mediate the impact of culture, society, economic conditions, living standards, and other similar background factors. The aim of this study was to determine factors associated with fertility status among the reproductive age group.
Methods: The data for this study was extracted from Ethiopia mini demographic and health survey 2019. The study involved 8885 household with reproductive age group in a weighted sample. The analysis was performed using STATA version 16 software. Using sampling weights for descriptive statistics and complex sample designs for inferential statistics, backward stepwise elimination was manually applied. Finally, statistical significance declared at the level of p-value < 0.05.
Result: The prevalence of fertility status in Ethiopia was observed to be 44.7%. In multivariate analysis the household female (AOR = 0.465, 95% CI: 0.418-0.517) had lower odds of fertility status in comparison to household male. The odds of fertility status were higher among the catholic religion as compared to the orthodox religion, (AOR = 1.615, 95% CI: 1.408-1.853). The odds of fertility status were lower in the Addis Ababa region in comparison to the Tigray region (AOR = 0.636, 95% CI: 0.495-0.818).
Fertility status odds were lower among those who could read only parts of the sentence literacy in comparison to those who were unable to read at all (AOR = 0.736, 95% CI: 0.623-0.869). The odds of fertility status were lower among primary educational levels as compared to no educational levels (AOR = 0.721, 95% CI: 0.632-0.823).
Regarding the household wealth index, the richest-wealth index (AOR = 0.832, 95% CI: 0.689-1.004) had lower odds of fertility status when compared with children from the poorest-wealth index. There was a lower odds of fertility status for electricity users compared with wood charcoal users using electricity as a cooking fuel (AOR = 0.825, 95% CI: 0.681-0.999). The odds of fertility status were higher among those with no toilet facility than those with pit latrines (AOR = 1.145, 95% CI: 1.009-1.298).
Conclusion: The high fertility status and population growth observed in this study. It shows significantly associated with household sex, region, literacy, educational level, religion, wealth index, cooking fuel, and toilet facility had a statistically significant association with fertility status. There are many factors contributing to economic development, including access to education and media, as well as job opportunities in modern economic sectors. In addition to this, it is important to develop and maintain access of family planning services.
Groundnut grain yield responses to inoculation with Bradyrhizobium sp. and cyanobacteria
Authors: Andrade Diva Souza , Lovato Gisele Milani , Kaschuk Glaciela , Hungria Mariangela 
Published: January 2023

Abstract

Groundnut can obtain N from the N2 fixation in the symbiosis with rhizobia and inoculation with selected strains can improve grain yields. We report the results from four field experiments, aiming to verify if microbial inoculants may improve groundnut performance, through the effects of single inoculation with Bradyrhizobium sp. (SEMIA6144), of co-inoculation Arthrospira platensis IPR7059 or Synechocystis sp. IPR7061, and of the N fertilization with 100 kg ha− 1 of N on plant growth, nodulation, N accumulated in tissues, grain protein, and grain yield. There were no effects of inoculation treatments and N-fertilizer on shoot and root dry weights. In clayey soil, co-inoculation with Bradyrhizobium sp. and cyanobacteria increased grain productivity by an average of 19% compared to the non-inoculated control. In this clayey soil with higher P content, regardless of whether co-inoculated with Bradyrhizobium sp. and cyanobacteria or single inoculated, grain productivity was 16% higher on average compared to nitrogen fertilizer. In conclusion, it was clear that success of rhizobia inoculation in groundnut is dependent on the soil, probably due to P limitation, and weather conditions.