bluuebunny/crossref_metadata_2025_split huggingface dataset:
Digitale Tools zur Optimierung der interdisziplinären Zusammenarbeit und des Lern- und Wissenstransfers – Entwicklung und Erprobung im Baugewerbe durch das Projekt IN-DIG-O
Authors: Rothenbusch Sandra , Mehner Laura , Gersie Carola , Brümmer Gabriele , Landers Christoph , Springmeyer Roland , Gessnitzer Sina , Kauffeld Simone 
Published: January 2023

ZusammenfassungDas Baugewerbe wird – wenn auch langsam – digitalisiert (Telekom, 2020; Thonipara, Höhle, Proeger & Bizer, 2020). Betroffen sind Prozesse im Gebäudebau, bei denen mehrere Gewerke involviert sind. So sollen diese Prozesse beispielsweise durch Building Information Modeling (BIM) präziser, akkurater und schneller werden (Jacobsson & Merschbrock, 2018). Kleine und mittlere Unternehmen (KMU) verfügen jedoch häufig nicht über die benötigten Ressourcen und Kompetenzen, um adäquat an dieser Entwicklung zu partizipieren. Das Projekt IN-DIG-O unterstützt KMU zweifach: Es stellt mit dem digitalen Tool namens Koop-3D eine Ressource zur interdisziplinären Zusammenarbeit in der Planungs- und Ausführungsphase im Hausbau zur Verfügung, die sich an BIM orientiert und von Subunternehmen keine IT-Kenntnisse zur 3D-Planung erfordert. Parallel begleitet ein zweites digitales Tool – das LeWiT-Tool – gezielt die Optimierung des Kompetenzerwerbs der Mitarbeitenden von KMU. Mittels der Grundprinzipien der entwicklungsorientierten Evaluation (Kauffeld & Paulsen, 2018) fördert es eine offene Feedbackkultur sowie selbstbestimmte Zielsetzungen. Dadurch wird der Lerntransfer nach Weiterbildungen in den Arbeitsalltag und die Weitergabe des neuen Wissens an das Kollegium verbessert. Der vorliegende Beitrag gibt einen Einblick in die beiden digitalen Tools, stellt Evaluationsergebnisse vor und zieht Learnings aus der Entwicklungs- und Erprobungsphase der digitalen Tools.
Arbeitsgestaltung durch Kompetenzvermittlung in VR
Authors: Weigel Andreas , Baumgart Thorben Lukas , Heinlein Michael , Huchler Norbert , Niehaves Björn , Sauter Louisa , Schmallenbach Anne , Staiger Benjamin , Wittal Regina 
Published: January 2023

ZusammenfassungDie Arbeitswelt und ihre Gestaltung befinden sich in einem stetigen Wandel. Der Einsatz neuer Technologien trägt dazu bei, die Innovationskraft und auch die allgemeine Attraktivität eines Unternehmens zu steigern. Dennoch müssen Unternehmen abwägen, ob ein solcher Einsatz auch unter wirtschaftlichen Gesichtspunkten erfolgsversprechend ist. VR-Technologien sind in den letzten Jahren deutlich erschwinglicher geworden und ihre Einsatzgebiete haben sich kontinuierlich weiterentwickelt. Die Gestaltung von virtuellen Umgebungen bietet umfangreiche Möglichkeiten. So nutzen Unternehmen virtuelle Showrooms zur Unterstützung des Verkaufsprozesses, setzen VR-Trainingsszenarien für die Aus- und Weiterbildung ihrer Mitarbeiter*innen ein, planen virtuelle Veranstaltungen als Antwort auf die Restriktionen der COVID-19 Pandemie oder beschäftigen sich mit virtuellen Kompetenzassistenten. Die Potentiale von VR-Technologien sind dabei weitreichend und können durch einen gezielten Einsatz vielversprechende Lösungen bieten. Das Projekt aSTAR verfolgte das Ziel, die Kompetenzvermittlung zwischen Konstrukteur*innen und Servicemitarbeiter*innen durch eine VR-Technologie zu unterstützen. Zu diesem Zweck wurden zunächst VR-Simulationen der Montage- und Wartungsszenarien am Kran entwickelt. Im Verlauf des Projektes entstand parallel eine VR-Software, die eine individuelle Gestaltung der VR-Umgebung ermöglicht. In die Software können unterschiedliche Kranmodelle sowie Umgebungen und Objekte geladen und flexibel platziert werden. Anschließend lassen sich Arbeitsschritte und -abläufe definieren, welche dann in der VR-Umgebung erlebt und bearbeitet werden können. Darüber hinaus sollte durch die VR-Entwicklung eine Möglichkeit entstehen, den CAD-Entwurf einfach in die VR zu übertragen (CAD2VR). Dies würde es den Konstrukteur*innen erlauben, ihren CAD-Entwurf in die VR zu laden und diesen dort aus einer Montage- und Serviceperspektive zu bewerten und bei Bedarf anzupassen. Durch die kontinuierliche Evaluation und Erhebung qualitativer Daten durch die Endanwender*innen konnte die Integration der VR-Technologie in bestehende Arbeitsprozesse aus vielen Perspektiven betrachtet werden. Somit können nun Strategien und Richtlinien formuliert werden, die die Integration der genannten VR-Szenarien und der CAD2VR-Anwendung unterstützen und übertragbare Ansätze für die Praxis liefern. Zusätzlich zu den VR-Technologien wurde eine Wissensplattform für die Montage- und Wartung am Kran aufgesetzt. Diese hatte zum Ziel, basierend auf einem intelligenten Suchalgorithmus, durch das Scannen von z. B. QR-Codes Informationen (Bedienungsanleitungen, Zusatzinformationen für bestimmte Krantypen) zur Montage- und Wartungsunterstützung bereitzustellen.
Automorphisms of finite order, periodic contractions, and Poisson-commutative subalgebras of $${\mathcal {S}}({\mathfrak g})$$
Authors: Panyushev Dmitri I. , Yakimova Oksana S. 
Published: January 2023

AbstractLet $${\mathfrak g}$$
g
be a semisimple Lie algebra, $$\vartheta \in \textsf{Aut}({\mathfrak g})$$

ϑ
∈
Aut
(
g
)

a finite order automorphism, and $${\mathfrak g}_0$$

g
0

the subalgebra of fixed points of $$\vartheta $$
ϑ
. Recently, we noticed that using $$\vartheta $$
ϑ
one can construct a pencil of compatible Poisson brackets on $${\mathcal {S}}({\mathfrak g})$$

S
(
g
)

, and thereby a ‘large’ Poisson-commutative subalgebra $${\mathcal {Z}}({\mathfrak g},\vartheta )$$

Z
(
g
,
ϑ
)

of $${\mathcal {S}}({\mathfrak g})^{{\mathfrak g}_0}$$

S

(
g
)

g
0

. In this article, we study invariant-theoretic properties of $$({\mathfrak g},\vartheta )$$

(
g
,
ϑ
)

that ensure good properties of $${\mathcal {Z}}({\mathfrak g},\vartheta )$$

Z
(
g
,
ϑ
)

. Associated with $$\vartheta $$
ϑ
one has a natural Lie algebra contraction $${\mathfrak g}_{(0)}$$

g

(
0
)

of $${\mathfrak g}$$
g
and the notion of a good generating system (=g.g.s.) in $${\mathcal {S}}({\mathfrak g})^{\mathfrak g}$$

S

(
g
)

g

. We prove that in many cases the equality $$\mathrm{ind\,}{\mathfrak g}_{(0)}=\mathrm{ind\,}{\mathfrak g}$$

ind

g

(
0
)

=

ind

g

holds and $${\mathcal {S}}({\mathfrak g})^{\mathfrak g}$$

S

(
g
)

g

has a g.g.s. According to V. G. Kac’s classification of finite order automorphisms (1969), $$\vartheta $$
ϑ
can be represented by a Kac diagram, $$\mathcal {K}(\vartheta )$$

K
(
ϑ
)

, and our results often use this presentation. The most surprising observation is that $${\mathfrak g}_{(0)}$$

g

(
0
)

depends only on the set of nodes in $$\mathcal {K}(\vartheta )$$

K
(
ϑ
)

with nonzero labels, and that if $$\vartheta $$
ϑ
is inner and a certain label is nonzero, then $${\mathfrak g}_{(0)}$$

g

(
0
)

is isomorphic to a parabolic contraction of $${\mathfrak g}$$
g
.
Spontaneous Retroperitoneal Haemorrhage: Efficacy of Conservative Management and Embolisation
Authors: Lukies Matthew , Gipson Jacob , Tan Sia Yang , Clements Warren 
Published: January 2023

Abstract
Purpose
To assess the efficacy of conservative management and embolisation in patients with spontaneous retroperitoneal haemorrhage.

Methods
Single-centre retrospective case–control study of patients with spontaneous retroperitoneal haemorrhage treated conservatively or with embolisation. Patients aged ≥ 18 years were identified from CT imaging reports stating a diagnosis of retroperitoneal haemorrhage or similar and images reviewed for confirmation. Exclusion criteria included recent trauma, surgery, retroperitoneal vascular line insertion, or other non-spontaneous aetiology.
Datapoints analysed included treatment approach (conservative or embolisation), technical success, clinical success, and mortality outcome.

Results
A total of 54 patients met inclusion criteria, who were predominantly anticoagulated (74%), male (72%), older adults (mean age 69 years), with active haemorrhage on CT (52%). Overall mortality was 15%. Clinical success was more likely with conservative management (36/38) than embolisation (9/16; p < 0.01), and all-cause (1/38 vs 7/16; p < 0.01) and uncontrolled primary bleeding (1/38 vs 5/16; p < 0.01) mortality were higher with embolisation. However, embolised patients more commonly had active bleeding on CT (15/38 vs 13/16; p < 0.01), shock (5/38 vs 6/16; p < 0.04), and higher blood transfusion volumes (mean 2.2 vs 5.9 units; p < 0.01). After one-to-one propensity score matching, differences in clinical success (p = 0.04) and all-cause mortality (p = 0.01) remained; however, difference in uncontrolled primary bleeding mortality did not (p = 0.07).

Conclusion
Conservative management of SRH is likely to be effective in most patients, even in those who are anticoagulated and haemodynamically unstable, with variable success seen after embolisation in a more unstable patient group, supporting the notion that resuscitation and optimisation of coagulation are the most vital components of treatment.
Super-resolution microscopy reveals the number and distribution of topoisomerase IIα and CENH3 molecules within barley metaphase chromosomes
Authors: Kubalová Ivona , Weisshart Klaus , Houben Andreas , Schubert Veit 
Published: January 2023

AbstractTopoisomerase IIα (Topo IIα) and the centromere-specific histone H3 variant CENH3 are key proteins involved in chromatin condensation and centromere determination, respectively. Consequently, they are required for proper chromosome segregation during cell divisions. We combined two super-resolution techniques, structured illumination microscopy (SIM) to co-localize Topo IIα and CENH3, and photoactivated localization microscopy (PALM) to determine their molecule numbers in barley metaphase chromosomes. We detected a dispersed Topo IIα distribution along chromosome arms but an accumulation at centromeres, telomeres, and nucleolus-organizing regions. With a precision of 10-50 nm, we counted ~ 20,000-40,000 Topo IIα molecules per chromosome, 28% of them within the (peri)centromere. With similar precision, we identified ~13,500 CENH3 molecules per centromere where Topo IIα proteins and CENH3-containing chromatin intermingle. In short, we demonstrate PALM as a useful method to count and localize single molecules with high precision within chromosomes. The ultrastructural distribution and the detected amount of Topo IIα and CENH3 are instrumental for a better understanding of their functions during chromatin condensation and centromere determination.
Biphenotypic sinonasal sarcoma with PAX3::MAML3 fusion transforming into high-grade rhabdomyosarcoma: report of an emerging rare phenomenon
Authors: Meyer Anders , Klubíčková Natálie , Mosaieby Elaheh , Grossmann Petr , Kalmykova Antonina , Koshyk Olena , Michal Michael 
Published: January 2023

AbstractWe report a case of a 67-year-old male patient with a sinonasal tumor that showed areas of classic biphenotypic sinonasal sarcoma (BSNS) which in some sections sharply transitioned into high-grade rhabdomyosarcoma. Immunohistochemically, the conventional BSNS parts showed S100 protein, SMA, PAX7, and focal MyoD1 expression, whereas desmin and myogenin were negative. In contrast, the cells in high-grade areas expressed desmin, MyoD1, myogenin, and PAX7, while being negative for S100 protein and SMA. Using the Archer FusionPlex assay, the classical PAX3::MAML3 gene fusion was detected. FISH for PAX3 and MAML3 confirmed a break of these genes in both components. Despite aggressive therapy, the tumor progression resulted in the patient’s death. The herein presented case, together with 2 previously published cases of BSNS with high-grade transformation, helps to better understand this novel phenomenon. Although the risk for such transformation appears low, it has important clinical and diagnostic implications which are discussed.
Classification of barely visible impact damage in composite laminates using deep learning and pulsed thermographic inspection
Authors: Deng Kailun , Liu Haochen , Yang Lichao , Addepalli Sri , Zhao Yifan 
Published: January 2023

AbstractWith the increasingly comprehensive utilisation of Carbon Fibre-Reinforced Polymers (CFRP) in modern industry, defects detection and characterisation of these materials have become very important and draw significant research attention. During the past 10 years, Artificial Intelligence (AI) technologies have been attractive in this area due to their outstanding ability in complex data analysis tasks. Most current AI-based studies on damage characterisation in this field focus on damage segmentation and depth measurement, which also faces the bottleneck of lacking adequate experimental data for model training. This paper proposes a new framework to understand the relationship between Barely Visible Impact Damage features occurring in typical CFRP laminates to their corresponding controlled drop-test impact energy using a Deep Learning approach. A parametric study consisting of one hundred CFRP laminates with known material specification and identical geometric dimensions were subjected to drop-impact tests using five different impact energy levels. Then Pulsed Thermography was adopted to reveal the subsurface impact damage in these specimens and recorded damage patterns in temporal sequences of thermal images. A convolutional neural network was then employed to train models that aim to classify captured thermal photos into different groups according to their corresponding impact energy levels. Testing results of models trained from different time windows and lengths were evaluated, and the best classification accuracy of 99.75% was achieved. Finally, to increase the transparency of the proposed solution, a salience map is introduced to understand the learning source of the produced models.
Loss of lumbar disc height with age and its impact on pain and sensitivity associated behaviors in mice
Authors: Vincent Kathleen F. , Bundock Jacqueline , Dona Chethana Prabodhanie Gallage , Chenna Srish S. , Mohanty Sarthak , Saini Chandan , Hong Justin , Albert Todd J. , Dahia Chitra L. 
Published: January 2023

Abstract
Purpose
Aging is a risk factor for several debilitating conditions including those related to chronic back pain and intervertebral disc degeneration, both of which have no cure. Mouse models are useful tools for studying disc degeneration and chronic back pain in a tightly controlled and clinically relevant aging environment. Moreover, mice offer the advantage of carrying out longitudinal studies to understand the etiology and progression of disc pathology induced by genetic or surgical strategies. Previously, age-related behavioral trends of discomfort and enhanced nociception in mice were reported; however, whether these measures are mediated by structural and pathological changes in the disc is unknown.

Methods
The goal of the present observational study was to identify behavioral correlates of age-related degenerative changes in the disc. Towards this, we collected radiographs from 150 mice (77 females) between three and 23 months of age and measured the disc height index for each level of lumbar disc. Behavioral measures were collected on several of these mice which included rearing and distance travelled in an open field test; time spent in rearing, reaching, immobile, and self-suspended in the tail suspension test; bilateral hind paw licking in response to cold allodynia using acetone; and unilateral hind paw licking in response to heat hyperalgesia using capsaicin.

Results
Results show that the lower lumbar discs lose height with age and these changes are independent of body composition measures including body weight, bone mineral density, fat mass, lean weight mass, percent fat mass, and percent lean mass. Disc height positively correlates with rearing and mobility in the open field test, immobility in the tail suspension test, and thermal hyperalgesia. Disc height negatively correlates with cold allodynia and rearing in the tail suspension test. Furthermore, mediation analysis shows that the lumbosacral disc significantly mediates the effect of age on rearing in the open field test, but not cold allodynia, suggesting this behavior is a useful measure of age-related axial discomfort due to disc degeneration.

Conclusion
In summary, the findings from the current study show that disc height are associated with measures of axial discomfort and nociception in mice.
Clinical and microbiological efficacy of indocyanine green-based antimicrobial photodynamic therapy as an adjunct to non-surgical treatment of periodontitis: a randomized controlled clinical trial
Authors: Annunziata Marco , Donnarumma Giovanna , Guida Agostino , Nastri Livia , Persico Gerardo , Fusco Alessandra , Sanz-Sánchez Ignacio , Guida Luigi 
Published: January 2023

Abstract
Objectives
The aim of the present randomized clinical trial (RCT) with a parallel arm design was to evaluate the clinical and microbiological efficacy of repeated ICG-aPDT as an adjunct to full-mouth subgingival debridement in the treatment of periodontitis.

Materials and methods
Twenty-four periodontitis patients were treated with full-mouth ultrasonic subgingival debridement (FMUD). Initial sites with probing depth (PD) > 4 mm were randomly assigned to receive the test (ICG-aPDT with an 810 nm diode laser) or the control treatment (off-mode aPDT) one and four weeks after FMUD. Clinical parameters were registered after 3 and 6 months. The presence of the main periodontal pathogens in subgingival samples was assessed with real-time PCR.

Results
Both treatment modalities resulted in significant clinical improvements at 3 and 6 months. The only significant differences in favour of the test group were found at 6 months for a higher PD reduction in initial deep pockets (PD ≥ 6 mm) and a higher percentage of closed pockets (PD ≤ 4 mm/no bleeding on probing). Limited microbiological changes were observed in both groups after treatment with no inter-group difference, except for a more significant reduction in Aggregatibacter actinomycetemcomitans and Parvimonas micra levels in the test group at 3 months.

Conclusion
The combination of repeated ICG-aPDT and FMUD provided no benefits except for selective clinical and microbiological improvements compared to FMUD alone.

Clinical relevance
Based on the obtained results, only limited adjunctive effects could be found for the combined use of ICG-aPDT and FMUD. Further, well-designed RCT with larger sample sizes are required to confirm these findings.

Trial registration
ClinicalTrials.gov NCT04671394.
What treatment outcomes matter in adolescent depression? A Q-study of priority profiles among mental health practitioners in the UK and Chile
Authors: Krause Karolin Rose , Calderón Ana , Pino Victor Gomez , Edbrooke-Childs Julian , Moltrecht Bettina , Wolpert Miranda 
Published: January 2023

AbstractEvidence-based and person-centred care requires the measurement of treatment outcomes that matter to youth and mental health practitioners. Priorities, however, may vary not just between but also within stakeholder groups. This study used Q-methodology to explore differences in outcome priorities among mental health practitioners from two countries in relation to youth depression. Practitioners from the United Kingdom (UK) (n = 27) and Chile (n = 15) sorted 35 outcome descriptions by importance and completed brief semi-structured interviews about their sorting rationale. By-person principal component analysis (PCA) served to identify distinct priority profiles within each country sample; second-order PCA examined whether these profiles could be further reduced into cross-cultural “super profiles”. We identified three UK outcome priority profiles (Reduced symptoms and enhanced well-being; improved individual coping and self-management; improved family coping and support), and two Chilean profiles (Strengthened identity and enhanced insight; symptom reduction and self-management). These could be further reduced into two cross-cultural super profiles: one prioritized outcomes related to reduced depressive symptoms and enhanced well-being; the other prioritized outcomes related to improved resilience resources within youth and families. A practitioner focus on symptom reduction aligns with a long-standing focus on symptomatic change in youth depression treatment studies, and with recent measurement recommendations. Less data and guidance are available to those practitioners who prioritize resilience outcomes. To raise the chances that such practitioners will engage in evidence-based practice and measurement-based care, measurement guidance for a broader set of outcomes may be needed.
Characterisation of the conveying effect of turned radial shaft seal counter-surfaces using a simplified hydrodynamic simulation model
Authors: Thielen Stefan , Subramanian Thirumanikandan , Sauer Bernd , Koch Oliver , Börner Richard , Junge Thomas , Schubert Andreas 
Published: January 2023

AbstractA typical sealing system for rotating shafts consists of the radial shaft sealing ring (RSS), the lubricant and the shaft counter-surface (SCS) of the rotating shaft. The properties of the machined surface of the SCS have an impact on the sealing system. The structural pattern of the SCS influences the lubricant flow along the axial direction. In this paper, a simplified micro scale hydrodynamic simulation model is presented in order to study and determine the axial flow of the lubricant induced by the SCS of the sealing system, isolated from the effects induced by the seal, to allow for a rating of the shaft surface. The influence of the seal was neglected to allow for a simplified simulation. Simulated shaft surfaces corresponding to different machining parameters of machined SCS are used as input. These variants of SCS were created using a kinematic model which simulates an ideal surface machining process of the shaft. A micro scale hydrodynamic simulation model is used to investigate the influence of machining parameters on the lubricant flow along the axial direction across the tribo-contact. From this investigation, the connection between parameters applied for machining of the SCS and conveying effects can be estimated. The simulation model is also validated with experimental results of hard turned shafts of different machining parameters. Differences between manufactured real surfaces and kinematically simulated surfaces are the cause of deviations between the results.
An empirical study of automated unit test generation for Python
Authors: Lukasczyk Stephan , Kroiß Florian , Fraser Gordon 
Published: January 2023

AbstractVarious mature automated test generation tools exist for statically typed programming languages such as Java. Automatically generating unit tests for dynamically typed programming languages such as Python, however, is substantially more difficult due to the dynamic nature of these languages as well as the lack of type information. Our Pynguin framework provides automated unit test generation for Python. In this paper, we extend our previous work on Pynguin to support more aspects of the Python language, and by studying a larger variety of well-established state of the art test-generation algorithms, namely DynaMOSA, MIO, and MOSA. Furthermore, we improved our Pynguin tool to generate regression assertions, whose quality we also evaluate. Our experiments confirm that evolutionary algorithms can outperform random test generation also in the context of Python, and similar to the Java world, DynaMOSA yields the highest coverage results. However, our results also demonstrate that there are still fundamental remaining issues, such as inferring type information for code without this information, currently limiting the effectiveness of test generation for Python.