bluuebunny/crossref_metadata_2025_split huggingface dataset:
Teachers’ Knowledge About Dental Trauma and its Management in Primary Schools in Jakarta, Indonesia
Authors: Mayasari Yufitri , Setia Wibowo Rahayu Dwi 
Published: July 2023

Traumatic dental injuries often occur in children aged 7-12 years during school hours. However, most teachers are not aware of first aid for traumatic dental injuries. There are 2 types of elementary schools, namely public elementary schools and private elementary schools. This study aims to explain the difference in knowledge about traumatic dental injury and its first aid management between public and private school teachers. Analytical research was conducted using a cross sectional approach and the sampling method was carried out using purposive sampling. Questionnaires in the form of Google Forms were used to collect data. Data were statistically analysed using Chi-square test for any correlation. Based on the results of the study that there is no significant difference in knowledge between public and private school teachers. The highest p-value is 0.752 and the lowest p-value is 0.102 (p > 0.05). So it can be concluded that this study did not find a significant difference in knowledge about first aid for traumatic dental injuries between public and private school teachers.
Alimentos transgénicos en México: rol económico e industrial
Authors: Ayala Jerónimo David Andrés 
Published: July 2023

Los alimentos transgénicos cumplen un rol determinante en la industria alimentaria mexicana con antecedentes históricos en lo económico y transcendental para la agricultura. Esta investigación, de corte documental, tiene como objetivo examinar los transgénicos en territorio mexicano y las ventajas que ha tenido sobre la agricultura.
El interés de esta investigación radica en el uso de los transgénicos para el crecimiento económico en México, así como el análisis de la legalidad y bioética en la producción de alimentos transgénicos.
Bayu Wetan As An Inspiration For The Percussion Of The Hips Creations | Bayu Wetan Sebagai Inspirasi Tabuh Kreasi Pepanggulan
Authors: Putra Dwi Antara , Yulianti Ni Ketut Dewi 
Published: July 2023

Garapan ini dituangkan ke dalam bentuk komposisi Tabuh Kreasi Pepanggulan. Beranalogi dengan ungkapan rasa si penata melalui fenomena alam hembusan angin timur. Ide ini muncul ketika penata sedang duduk di salah satu tempat duduk di rumah penata sendiri, dan penata merasakan hembusan angin yang datangnya dari arah timur yang berhembus dengan rapi dan membawa suasana keindahan, kesejukan dengan kekuatan angin tersebut penata merasakan bagaimana suasana pada pagi hari. Berpijak dari fenomena tersebut penata mendapatkan inspirasi untuk merealisaikan keindahan, kesejukan, dan kekuatan angin timur yang telah menghampiri jiwa si penata ke dalam sebuah bentuk komposisi Tabuh Kreasi Pepanggulan yang dikemas dengan menggunakan struktur Tri Angga yaitu Kawitan, Pengawak, dan Pengecet. Bayu dan wetan merupakan dua kata yang memiliki arti yang berbeda, akan tetapi penata akan membuat arti tersebut ke dalam satu garapan utuh. Kata “bayu” dalam Bahasa Sansekerta berarti angin, dan kata “wetan” berarti timur rupanya putih aksaranya “dang” dengan saktinya Sang Sadyoja (Bandem, 1986). Jadi “bayu wetan” dapat diartikan sebagai konsep filosopis dari Dewa Iswara yang menguasi arah timur dan sebagai pengendali arah mata angin di bagian timur.
Musical Composition “Segehan Wong” | Komposisi Karawitan “Segehan Wong”
Authors: Gung Wisnu I Gusti Ngurah Wisnu Dharma , Sudiana I Nyoman 
Published: July 2023

Segehan Wong merupakan sebuah upakara atau sesajen yang dimana sesajen tersebut adalah sebuah simbul sebagai bentuk perlawanan umat Hindu di bali terhadap Virus Covid-19 ini di ekspresikan dalam bentuk karya musik inovatif yang di sajikan dengan gambelan bali. Di mana memiliki bagian perbagian di mana di dalam bagian pertama itu adalah kepala dari segehan yang berwarna putih yang memiliki arti agar pemikiran nagatif dapat di atasi oleh kesucian di lanjutkan ke bagian kedua yang di mana itu di dalam segehan terdapat pada badan yang berwarna brumbun memiliki arti agar semua perasaan hadir dan terpancar dari hati yang paling dalam dan juga yang meliputi kedua tangan yang di mana tangan kiri berwarna kuning yang memiliki arti kemuliaan dan tangan kanan berwarna merah memiliki arti keberanian dan pada bagian ketiga meliputi kaki dari segehan yang di mana berwarna hitam yang memiliki arti berani melangkah melewati kegelapan dunia yang sedang hadir.
Use of online material in teaching general practice
Authors: Jorgensen Merete , Witt Klaus , Mäkelä Matrjukka , Siersma Volkert , Winther Bang Christine 
Published: July 2023

In the general practice course at Copenhagen University, students record videos of their consultations in general practice. At university, the videos are discussed with a teacher and peers. Simulated video consultations were produced to support learning. The aim of this study was to evaluate the effect of adding simulated consultation videos to standard teaching.
Final semester students (N=587) were assigned by the university to six groups and received more online teaching material one step at a time. A questionnaire and a test video consultation measured the change in students’ ability to identify patient-centered elements in a consultation pre-and post-course. Effect sizes were calculated as the difference between the pre-and post-course measures divided by the mean-variance before the course.
The overall teaching effect size (ES) was positive (0,67). A high average ES of 0.94 was found for the communication questions, which included most of the patient-centered elements. Introducing simulated video consultations did not increase awareness of patient-centered elements. However, an increase in clinical skills was demonstrated.
Showing simulated video consultations from general practice increase the students awareness of clinical cases in general practice and can be supplement to the clinical teaching.
Presenting a sham treatment as personalised increases the placebo effect in a randomised controlled trial
Authors: Sandra Dasha A , Olson Jay A , Langer Ellen J , Roy Mathieu 
Published: July 2023

Background:Tailoring interventions to patient subgroups can improve intervention outcomes for various conditions. However, it is unclear how much of this improvement is due to the pharmacological personalisation versus the non-specific effects of the contextual factors involved in the tailoring process, such as the therapeutic interaction. Here, we tested whether presenting a (placebo) analgesia machine as personalised would improve its effectiveness.Methods:We recruited 102 adults in two samples (N1=17, N2=85) to receive painful heat stimulations on their forearm. During half of the stimulations, a machine purportedly delivered an electric current to reduce their pain. The participants were either told that the machine was personalised to their genetics and physiology, or that it was effective in reducing pain generally.Results:Participants told that the machine was personalised reported more relief in pain intensity than the control group in both the feasibility study (standardised β=−0.50 [–1.08, 0.08]) and the pre-registered double-blind confirmatory study (β=−0.20 [–0.36, –0.04]). We found similar effects on pain unpleasantness, and several personality traits moderated the results.Conclusions:We present some of the first evidence that framing a sham treatment as personalised increases its effectiveness. Our findings could potentially improve the methodology of precision medicine research and inform practice.Funding:This study was funded by the Social Science and Humanities Research Council (93188) and Genome Québec (95747).
Development of a circHIPK3-based ceRNA network and identification of mRNA signature in breast cancer patients harboring BRCA mutation
Authors: Lian Qi-xin , Song Yang , Han Lili , Wang Zunxian , Song Yinhui 
Published: July 2023

Background
Exploring the regulatory network of competing endogenous RNAs (ceRNAs) as hallmarks for breast cancer development has great significance and could provide therapeutic targets. An mRNA signature predictive of prognosis and therapy response in BRCA carriers was developed according to circular RNA homeodomain-interacting protein kinase 3 (circHIPK3)-based ceRNA network.

Method
We constructed a circHIPK3-based ceRNA network based on GSE173766 dataset and identified potential mRNAs that were associated with BRCA mutation patients within this ceRNA network. A total of 11 prognostic mRNAs and a risk model were identified and developed by univariate Cox regression analysis and the LASSO regression analysis as well as stepAIC method. Genomic landscape was treated by mutect2 and fisher. Immune characteristics was analyzed by ESTIMATE, MCP-counter. TIDE analysis was conducted to predict immunotherapy. The clinical treatment outcomes of BRCA mutation patients were assessed using a nomogram. The proliferation, migration and invasion in breast cancer cell lines were examined using CCK8 assay and transwell assay.

Result
We found 241 mRNAs within the circHIPK3-based ceRNA network. An 11 mRNA-based signature was identified for prognostic model construction. High risk patients exhibited dismal prognosis, low response to immunotherapy, less immune cell infiltration and tumor mutation burden (TMB). High-risk patients were sensitive to six anti-tumor drugs, while low-risk patient were sensitive to 47 drugs. The risk score was the most effective on evaluating patients’ survival. The robustness and good prediction performance were validated in The Cancer Genome Atlas (TCGA) dataset and immunotherapy datasets, respectively. In addition, circHIPK3 mRNA level was upregulated, and promoted cell viability, migration and invasion in breast cancer cell lines.

Conclusion
The current study could improve the understanding of mRNAs in relation to BRCA mutation and pave the way to develop mRNA-based therapeutic targets for breast cancer patients with BRCA mutation.
Chemical weathering rates and controlling mechanisms of glacial catchments within different climate regimes in the Tibetan Plateau
Authors: Guo Xiao , Zhao Zimiao , Liu Wenjing , Sun Huiguo , Xu Zhifang 
Published: July 2023

Background
Continental weathering plays an important role in regulating atmospheric CO2 levels. Chemical weathering in glacial areas has become an intensely focused topic in the background of global change compared with other terrestrial weathering systems. However, research on the weathering of the glacial areas in the Yarlung Tsangpo River Basin (YTRB) is still limited.

Methods
In this article, the major ions of the Chaiqu and Niangqu catchments in the YTRB have been investigated to illustrate the chemical weathering rates and mechanisms of the glacier areas in the YTRB.

Results
Ca2+ and HCO${}_{3}^{-}$ dominate the major ions of the Chaiqu and Niangqu rivers, accounting for about 71.3% and 69.2% of the TZ+ of the Chaiqu (the total cations, TZ+ = Na+ + K+ + Ca2 + + Mg2+, in µeq/L), and about 64.2% and 62.6% of the TZ+ of the Niangqu. A Monte Carlo model with six end-members is applied to quantitatively partition the dissolved load sources of the catchments. The results show that the dissolved loads of the Chaiqu and Niangqu rivers are mainly derived from carbonate weathering (accounting for about 62.9% and 79.7% of the TZ+, respectively), followed by silicate weathering (about 25.8% and 7.9% of the TZ+, respectively). The contributions of precipitation and evaporite to the Chaiqu rivers are about 5.0% and 6.2%, and those to the Niangqu rivers are about 6.3% and 6.2%. The model also calculated the proportion of sulfuric acid weathering in the Chaiqu and Niangqu catchments, which account for about 21.1% and 32.3% of the TZ+, respectively. Based on the results calculated by the model, the carbonate and silicate weathering rates in the Chaiqu catchment are about 7.9 and 1.8 ton km−2 a−1, and in the Niangqu catchment, the rates are about 13.7 and 1.5 ton km−2 a−1. The associated CO2 consumption in the Chaiqu catchment is about 4.3 and 4.4 × 104 mol km−2 a−1, and about 4.3 and 1.3 × 104 mol km−2 a−1 in the Niangqu catchment. The chemical weathering rates of the glacier areas in the YTRB show an increasing trend from upstream to downstream. Studying the weathering rates of glacier catchments in the Tibetan Plateau (TP) reveals that the chemical weathering rates of the temperate glacier catchments are higher than those of the cold glacier catchments and that lithology and runoff are important factors in controlling the chemical weathering of glacier catchments in the TP. The chemical weathering mechanisms of glacier areas in the YTRB were explored through statistical methods, and we found that elevation-dependent climate is the primary control. Lithology and glacial landforms rank second and third, respectively. Our results suggest that, above a certain altitude, climate change caused by tectonic uplift may inhibit chemical weathering. There is a more complex interaction between tectonic uplift, climate, and chemical weathering.
A Qualitative Study of Managerial Factors Influencing the Performance of Shehia Administration Practice in Urban District Unguja
Authors: Rashid Rahma Juma , Waqif Ruqayyah Mohammed , Abdallah Ahmed Ally , Hamad Abdalla Ussi 
Published: July 2023

The main concern of this paper is to explore the managerial factors influencing the performance of Shehia administration practices in Urban District Unguja. The study adopted a case study design. The data was collected through face to face interviews and focus group discussion with the total of 44 respondents selected purposively from the four Shehias of Urban District Unguja. Qualitative Data were analyzed by thematic Analysis.
The findings of this study revealed that there are themes of factors that influence the performance of Shehia administration practices in Urban District Unguja such as the, lack of autonomy in decision making process, low co-operation between local government and Shehias, as well as inadequate resources and facilities. Therefore, through this study; the researcher recommends that there should be intervention of government to support Shehias in establishing economic projects. Provision of adequate and modern equipment on the Shehia administration activities; performing ongoing training to the Shehas and establishment of good policy that will allow a competent Shehas to be appointed to the position of Shehas so as to make sure administration activities is being done effectively.
Subacute aphasia recovery is associated with resting‐state connectivity within and beyond the language network
Authors: Stockbridge Melissa D. , Faria Andreia V. , Fridriksson Julius , Rorden Chris , Bonilha Leonardo , Hillis Argye E. 
Published: July 2023

AbstractObjectiveTo examine changes to connectivity after aphasia treatment in the first 3 months after stroke.MethodsTwenty people experiencing aphasia within the first 3 months of stroke completed MRI before and immediately following 15 hours of language treatment. They were classified based on their response to treatment on a naming test of nouns as either high responders (10% improvement or more), or low responders (<10% improvement). Groups were similar in age, gender distribution, education, days since stroke, stroke volume, and baseline severity. Resting‐state functional connectivity analysis was limited to the connectivity of the left fusiform gyrus with the bilateral inferior frontal gyrus, supramarginal gyrus, angular gyrus, and superior, middle, and inferior temporal gyrus, based on previous studies showing the importance of left fusiform gyrus in naming performance.ResultsBaseline ipsilateral connectivity between the left fusiform gyrus and the language network was similar between high and low responders to therapy when controlling for stroke volume. Following therapy, change in connectivity was significantly greater among high responders between the left fusiform gyrus and the ipsilateral and contralateral pars triangularis, ipsilateral pars opercularis and superior temporal gyrus, and contralateral angular gyrus when compared with low responders.InterpretationAn account of these findings incorporates primarily proximal connectivity restoration, but also potentially reflects select contralateral compensatory reorganization. The latter is often associated with chronic recovery, reflecting the transitional nature of the subacute period.
Patterns of Imaging Requests By General Practitioners for People With Musculoskeletal Complaints: An Analysis From a Primary Care Database
Authors: Haas Romi , Gorelik Alexandra , O'Connor Denise A. , Pearce Christopher , Mazza Danielle , Buchbinder Rachelle 
Published: July 2023

ObjectiveThe aim of this study was to examine imaging requested by general practitioners (GPs) for patients with low back, neck, shoulder, and knee complaints over 5 years (2014–2018).MethodsThis analysis from the Australian Population Level Analysis and Reporting database included patients presenting with a diagnosis of low back, neck, shoulder, and/or knee complaints. Eligible imaging requests included low back and neck x‐ray, computed tomography (CT), and magnetic resonance imaging (MRI); knee x‐ray, CT, MRI, and ultrasound; and shoulder x‐ray, MRI, and ultrasound. We determined number of imaging requests and examined their timing, associated factors, and trends over time. Primary analysis included imaging requests from 2 weeks before diagnosis to 1 year after diagnosis.ResultsThere were 133,279 patients (57% low back, 25% knee, 20% shoulder, and 11% neck complaints). Imaging was most common among those with a shoulder (49%) complaint, followed by knee (43%), neck (34%), and low back complaints (26%). Most requests occurred simultaneously with the diagnosis. Imaging modality varied by body region and, to a lesser extent, by gender, socioeconomic status, and primary health network. For low back, there was a 1.3% (95% confidence interval [95% CI] 1.0–1.6) annual increase in proportion of MRI and a concomitant 1.3% (95% CI 0.8–1.8) decrease in CT requests. For neck, there was a 3.0% (95% CI 2.1–3.9) annual increase in proportion of MRI and a concomitant 3.1% (95% CI 2.2–4.0) decrease in x‐ray requests.ConclusionGPs commonly request early diagnostic imaging for musculoskeletal complaints at odds with recommended practice. We observed a trend towards more complex imaging for neck and back complaints.
Liquid–Solid Triboelectric Probes for Real‐Time Monitoring of Sucrose Fluid Status
Authors: Liu Tao , Mo Wenfeng , Zou Xuelian , Luo Bin , Zhang Song , Liu Yanhua , Cai Chenchen , Chi Mingchao , Wang Jinlong , Wang Shuangfei , Lu Dengjun , Nie Shuangxi 
Published: July 2023

AbstractTriboelectric probes have rapidly developed as an efficient tool for understanding contact electrification at liquid–solid interfaces. However, the liquid–solid electrification process is susceptible to interference from chemical components in mixed solutions, severely limiting the potential applications of triboelectric probes in various liquid environments. This study for the first time reports a triboelectric probe capable of sucrose solution concentration sensing, finding that the dissolution of sucrose destroys the hydrogen bond network between water molecules and forms sucrose–water hydrogen bonds, which alters the fluid mechanics characteristics of the solution and enhances its conductivity, thereby reducing the droplet size and causing an ion charge shielding effect that significantly affects the electron transfer in liquid–solid contact electrification. Owing to the feedback of the triboelectric probe on the sucrose concentration gradient‐type sensing electrical signals, efficient sensing of sucrose solution was achieved (sensitivity of −0.0038%−1, response time of 90 ms). The triboelectric probe is also used as a wireless smart terminal to enable real‐time detection of sucrose solution. This work contributes to the understanding of the structure–function relationship between micro hydrogen bonding and macro performance, and provides a promising solution for building sustainable intelligent sensors.
Plasmonic Nanoneedle Arrays with Enhanced Hot Electron Photodetection for Near‐IR Imaging
Authors: Zhang Cheng , Huang Binglin , Li Haoyu , Chen Hui , Yu Tong , Zhang Bingchang , Wang Shaojun , Liu Changxu , Luo Yu , Maier Stefan A. , Li Xiaofeng 
Published: July 2023

AbstractHot electron photodetection based on metallic nanostructures is attracting significant attention due to its potential to overcome the limitation of the traditional semiconductor bandgap. To enable efficient hot electron photodetection for practical applications, it is necessary to achieve broadband and perfect light absorption within extremely thin plasmonic nanostructures using cost‐effective fabrication techniques. In this study, an ultrahigh optical absorption (up to 97.3% in average across the spectral range of 1200−2400 nm) is demonstrated in the ultrathin plasmonic nanoneedle arrays (NNs) with thickness of 10 nm, based on an all‐wet metal‐assisted chemical etching process. The efficient hot electron generation, transport, and injection at the nanoscale apex of the nanoneedles facilitate the photodetector to achieve a record low noise equivalent power (NEP) of 4.4 × 10−12 W Hz−0.5 at the wavelength of 1300 nm. The hot‐electron generation and injection process are elucidated through a transport model based on a Monte Carlo approach, which quantitatively matches the experimental data. The photodetector is further integrated into a light imaging system, as a demonstration of the exceptional imaging capabilities at the near‐IR regime. The study presents a lithography‐free, scalable, and cost‐effective approach to enhance hot electron photodetection, with promising prospects for future imaging systems.
Biomimetic Artificial Tetrachromatic Photoreceptors Based on Fully Light‐Controlled 2D Transistors
Authors: Wu Rongqi , Liu Xiaochi , Yuan Yahua , Wang Zhongwang , Jing Yumei , Sun Jian 
Published: July 2023

AbstractArtificial photoreceptors offer a promising solution for developing biomimetic vision systems that incorporate in‐sensor processing, which can greatly reduce power consumption and operation latency compared to traditional machine vision systems. This work presents a tetrachromatic optical synaptic device based on a 2D tungsten diselenide optoelectronic p‐type transistor with a unique UV light‐activated surface electron doping layer. Fully light‐controlled bidirectional synaptic excitation and inhibition are demonstrated with visible and UV light stimuli, respectively, with a reasonable power density of <10 mW cm−2 that matches the imaging condition of a biological vision. The weight updates of up to 64 states, high dynamic range, and low nonlinearity are demonstrated for long‐term potentiation and depression behaviors. This artificial tetrachromatic photoreceptor can mimic the alert and foraging behaviors of a reindeer with low power consumption and enhanced signal contrast. Furthermore, it can be employed as an intelligent collision detection solution with in‐sensor processing capabilities. This bioinspired tetrachromatic photoreceptor offers a low‐cost, energy‐efficient, and low‐latency solution for future artificial machines.