bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Complete Mitochondrial Genome of the Freshwater Fish Onychostoma ovale (Cypriniformes, Cyprinidae): Genome Characterization and Phylogenetic Analysis
Authors: Zhang Renyi , Zhu Tingting , Luo Qi 
Published: June 2023

In this study, we sequenced and characterized the complete mitochondrial genome (mitogenome) of Onychostoma ovale. The mitogenome of O. ovale was 16,602 bp in length with 13 protein-coding genes (PCGs), 22 transfer RNA (tRNA) genes, 2 ribosomal RNA (rRNA) genes, and a control region. The nucleotide composition of the O. ovale mitogenome was 31.47% A, 24.07% T, 15.92% G, and 28.54% C, with a higher A + T content (55.54%) than G + C content (44.46%). All PCGs began with the standard ATG codon, except for the cytochrome c oxidase subunit 1 (COX1) gene and the NADH dehydrogenase 3 (ND3) gene with GTG, while six PCGs ended with incomplete termination codons (TA or T). The Ka/Ks ratios of 13 PCGs were all less than one, indicating that they were under purifying selection. All tRNA genes were folded into the typical cloverleaf secondary structures with the exception of tRNASer(AGY), whose dihydrouridine (DHU) arm was absent. The phylogenetic trees showed that Onychostoma and Acrossocheilus were classified into three clades. There was a mosaic relationship between Onychostoma and Acrossocheilus. Moreover, the phylogenetic tree analysis showed that O. rarum was the closest species to O. ovale. This study can provide a useful resource for further phylogeny and population genetic analyses of Onychostoma and Acrossocheilus.
Ocular Findings in Patients with Orbital Fractures: A 1-Year Prospective Study in a Tertiary Center
Authors: Asiri Mohammed , Aldowah Omir 
Published: June 2023

Background and Objectives: The aim of this study was to study the prevalence of ocular findings in patients with orbital fractures in a tertiary center in Saudi Arabia. Materials and methods: A cross-sectional observational study was performed. The participants were patients who presented with orbital trauma to the emergency department of King Saud Medical City (Riyadh, Saudi Arabia). Subjects included those diagnosed with isolated orbital fracture using clinical evaluation and CT examination. We performed direct evaluation of ocular findings for all patients. Variables studied included age, gender, site of ocular fracture, cause of trauma, side of fracture, and ocular findings. Results: In total, 74 patients with orbital fractures were included in this study (n = 74). Of the 74 patients, 69 (93.2%) were males and only 5 patients (6.8%) were females. The age range was 8-70 years, with a median age of 27 years. The 27.5–32.6-year age group was the most affected (95.0%). The left orbital bone was involved in the majority of bone fractures 48 (64.9%). The orbital floor (n = 52, 41.9%) and lateral wall (n = 31, 25.0%) were the most prevalent sites of bone fracture among the study patients. Road traffic accidents (RTAs) were the most common causes (64.9%) of orbital fractures, followed by assaults (16.2%) and then sports injuries and falls (9.5% and 8.1%, respectively). Animal attacks were the least cause of trauma (only 1 patient, 1.4%). The occurrence of ocular findings, either alone or in combination, showed that subconjunctival hemorrhage had the highest percentage (52.0%), followed by edema (17.6%) and ecchymosis (13.6%). A statistically significant correlation was reported between the site of bone fracture and orbital findings, with r = 0.251 * and p < 0.05. Conclusions: Subconjunctival bleeding, edema, and ecchymosis were the most frequent ocular abnormalities, in that order. There were a few instances of diplopia, exophthalmos, and paresthesia. Other ocular discoveries were incredibly uncommon. The location of bone fractures was found to be significantly correlated with ocular results.
Risk factors for early childhood caries (systematic review)
Authors: Li Xiang , Skakodub A. A. 
Published: June 2023

Relevance.Early childhood caries remains the most common chronic disease in children, having a significant impact on society around the world.Objective.To study all risk factors for early childhood caries identified from 2004 to 2023.Material and methods.The review analyzed and searched the literature in the databases MEDLINE, Embase, Cochrane CENTRAL, Cochrane Database of Systematic Reviews, PubMed and E-library using the keywords: caries, early childhood caries, dental diseases, risk factors in English and Russian, respectively. In addition, we studied links to the studies relevant to the topic and manually searched the references for potentially suitable publications. The systematic review finally included randomized controlled trials, meta-analysis and systematic reviews to identify risk factors for caries onset in early childhood over the past decade. The final sample included 31 papers covering 16 countries and published from 2004 to 2023.Results. The results of the studies established the main risk factors for early childhood caries development (oral hygiene factors, social-demographic factors and dietary factors), identified temporary risk factors (complicated pregnancy, calcium intake during pregnancy), and determined insufficiently studied risk factors.Conclusion. The data of the included studies confirm the multifactorial nature of caries onset in early childhood and the lack of quantitative analysis among all currently known factors, which could significantly reduce caries prevalence due to the conceptual treatment model.
Uptake and adoption of the NHS App in England: an observational study
Authors: KC Sukriti , Tewolde Salina , Laverty Anthony A , Costelloe Céire , Papoutsi Chrysanthi , Reidy Claire , Gudgin Bernard , Shenton Craig , Majeed Azeem , Powell John , Greaves Felix 
Published: June 2023

BackgroundTechnological advances have led to the use of patient portals that give people digital access to their personal health information. The NHS App was launched in January 2019 as a ‘front door’ to digitally enabled health services.AimTo evaluate patterns of uptake of the NHS App, subgroup differences in registration, and the impact of COVID-19.Design and settingAn observational study using monthly NHS App user data at general-practice level in England was conducted.MethodDescriptive statistics and time-series analysis explored monthly NHS App use from January 2019–May 2021. Interrupted time-series models were used to identify changes in the level and trend of use of different functionalities, before and after the first COVID-19 lockdown. Negative binomial regression assessed differences in app registration by markers of general-practice level sociodemographic variables.ResultBetween January 2019 and May 2021, there were 8 524 882 NHS App downloads and 4 449 869 registrations, with a 4-fold increase in App downloads when the COVID Pass feature was introduced. Analyses by sociodemographic data found 25% lower registrations in the most deprived practices (P<0.001), and 44% more registrations in the largest sized practices (P<0.001). Registration rates were 36% higher in practices with the highest proportion of registered White patients (P<0.001), 23% higher in practices with the largest proportion of 15–34-year-olds (P<0.001) and 2% lower in practices with highest proportion of people with long-term care needs (P<0.001).ConclusionThe uptake of the NHS App substantially increased post-lockdown, most significantly after the NHS COVID Pass feature was introduced. An unequal pattern of app registration was identified, and the use of different functions varied. Further research is needed to understand these patterns of inequalities and their impact on patient experience.
Efektifitas Pelayanan Pemeriksaan Fisik Barang Impor Dengan Penerapan Sistem Single Submission (Ssm) Kepabeanan Dan Karantina Melalui Joint Inspection Pada Kantor Pengawasan Dan Pelayanan Bea Dan Cukai Tipe Madya Pabean Belawan Sumatera Utara
Authors: Panggabean Rogers , Mardiana Siti , Adam Adam 
Published: June 2023

Kerja sama Bea Cukai dan Karantina dilakukan secara bertahap di pelabuhan-pelabuhan utama melalui Keputusan Dirjen Bea dan Cukai Nomor KEP-216/BC/2020 tentang Penerapan Secara Penuh (mandatory) Single Submission – Joint Inspection Bea Cukai dan Karantina di Pelabuhan Belawan tanggal 21 September 2020 sampai dengan saat ini. Pelaku Usaha (Importir/Eksportir/PPJK) mendapatkan kemudahan dengan hanya satu kali submit Permohonan Impor melalui SSm sistem Indonesia National Single Windows (INSW). Sistem INSW melakukan validasi data dan mengirimkan Pelaporan pemeriksaan karantina ke Badan Karantin, dan Data PIB dikirimkan ke DJBC. Berjalan selama kurang lebih tiga tahun, secara umum penerapan SSm ini masih ditemukan adanya kendala saat eksekusinya di lapangan sehingga berpotensi menyebabkan kepuasan pengguna jasa kembali menurun. Penelitian ini menggunakan Metode kualitatif deskriptif dengan pengumpulan data dilakukan melalui observasi, wawancara dan dokumentasi dan teknik analisa data yang digunakan adalah pengumpulan data, reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian menjelaskan Pelayanan Pemeriksaan Fisik Barang Impor Dengan Penerapan Single Submission (SSM) Kepabeanan dan Karantina Melalui Joint Inspection pada Kantor Pengawasan Dan Pelayanan Bea Dan Cukai Tipe Madya Pabean Belawan, Sumatera Utara masih ditemukan adanya kendala saat eksekusinya di lapangan. Beberapa hal perlu dilakukan perbaikan sebagai bagian dari proses adaptasi. Hal ini mencakup peningkatan infrastruktur pelabuhan Belawan yang harus semakin disempurnakan baik fisik dan non-fisik, termasuk kestabilan koneksi serta keamanan jaringan harus terus dijaga dan ditingkatkan karena layanan SSm-Joint Inspection ini erat kaitannya dengan kemampuan pengembangan teknologi informasi dan artificial intelligent.
KAJIAN LITERATUR: SUNAT PEREMPUAN DITINJAU DARI ASPEK UMUM DAN KESEHATAN
Authors: Fitri Kurniati  , Fujiana Fitri , Uray Fretty Hayati  
Published: June 2023

Background: Female genital mutilation raises pros and cons among the community because of its impact. There are still many parents who perform genital mutilation on their daughters. In addition, some parents choose not to circumcise their daughters. Objective: To analyze the general impact and health impact of female genital mutilation. Methods: a literature review by searching related articles through the Google Scholar database, Researchget and Science Direct. The keywords used in Indonesian are "sunat” and "perempuan" and "dampak" while in English, they are "female" and "genital mutilation" or "circumcision" and "consequences". The search found seven related articles which were then analyzed in a narrative review. Result: Female genital mutilation impacts health, including bleeding, bacterial infection, urinary tract infection, complications during childbirth, tetanus and shock. In addition to health problems, female circumcision is also associated with early marriage. Female circumcision is also called a tradition and an act that violates human rights. Conclusion: All articles reviewed explained that female genital mutilation harms general health and well-being. Female circumcision can harm the woman herself. It is hoped that nurses will provide more comprehensive education to the community regarding the dangers and impacts of female circumcision.
Keywords: female circumcision, female genital mutilation, the impact of female genital mutilation
HUBUNGAN TINGKAT PENGETAHUAN DENGAN KECEMASAN PASIEN TINDAKAN ENDOSKOPI
Authors: Redho Ahmad , Nofri Hasrianto  , Susismolia  
Published: June 2023

Endoskopi adalah alat untuk pemeriksaan bagian organ pada tubuh terutama saluran pencernaan secara visual pada target menggunakan alat yang terlihat pada monitor sejelas-jelasnya setiap kelainan organ yang diperiksa. Kecemasan pada endoskopi dipicu oleh suatu prosedur seperti rasa takut, rasa sakit dan ketidaknyamanan, informasi yang tidak memadai dan tidak tau apa yang diharapkan selama proses. Populasi pada penelitian ini adalah sebanyak 100 orang dengan sampel 80 orang. Metode pengumpulan sampel digunakan teknik accidental sampling. Metode analisis yang dipakai adalah analisis univariat dan bivariat. Uji validitas nilai r tabel didapatkan 0,4438. Realiabilitas DASS dengan tingkatan discriminant validity sebesar 0,91 berdasarkan penilaian cronbach's alpha. Analisis hubungan pengetahuan dengan kecemasan pasien endoskopi didapatkan dari 35 responden dengan pengetahuan baik terdapat 17 responden (21.3%) mengalami kecemasan ringan, sebanyak 15 orang mengalami kecemasan sedang (18.8%) dan sebanyak 3 orang (3.8%) mengalami kecemasan berat. Sebanyak 25 responden dengan pengetahuan cukup terdapat 10 responden (12.5%) mengalami kecemasan ringan, sebanyak 12 orang mengalami kecemasan sedang (15%) dan sebanyak 3 orang (3.8%) mengalami kecemasan berat. Dan sebanyak 20 responden dengan pengetahuan kurang terdapat 7 responden (8.8%) mengalami kecemasan ringan, sebanyak 4 orang mengalami kecemasan sedang (5.0%) dan sebanyak 9 orang (11.3%) mengalami kecemasan berat.. Hasil uji statistik Chi-Square menunjukkan ada hubungan pengetahuan dengan kecemasan pasien yang akan dilakukan endoskopi dimana nilai p < 0,05. Saran hasil penelitian diharapkan bisa di jadikan perawat sebagai intervensi keperawatan yang tepat untuk mengurangi kecemasan yang timbul akibat tindakan endoskopi.
HUBUNGAN TINGKAT PENGETAHUAN DAN SIKAP IBU TENTANG DEMAM DENGAN PENATALAKSANAAN DEMAM PADA ANAK DI PUSKESMAS HARAPAN RAYA PEKANBARU
Authors: Aulia Rinanda 
Published: June 2023

Demam lebih sering terjadi pada anak dibandingkan orang dewasa. Berdasarkan data dari Dinas Kesehatan Kota Pekanbaru, dari 21 Puskesmas yang ada di Kota Pekanbaru, didapatkan jumlah anak yang mengalami demam yang paling terbanyak tercatat di Puskesmas Harapan Raya yaitu 352 orang anak pada tahun 2016 dan tahun 2017 meningkat menjadi 387 orang anak. Penelitian ini bertujuan mengetahui hubungan tingkat pengetahuan dan sikap ibu tentang demam dengan penatalaksanaan demam pada anak diwilayah kerja Puskesmas Harapan Raya Pekanbaru, jenis penelitian ini menggunakan jenis penelitian kuantitatif dengan desain retrospektif, dengan populasi adalah ibu yang memiliki anak demam, dengan sampel sebanyak 57 orang. Pengambilan sampel menggunakan teknik consecutive sampling. Alat pengumpulan data menggunakan kuesioner dan analisa data dilakukan secara univariat dan bivariat. Hasil penelitian diperoleh terdapat hubungan antara pengetahuan ibu dengan penatalaksanaan demam anak dengan hasil uji chi square didapat (p = 0,0024 < 0,05) dan sikap ibu (p = 0,000 < 0,05). Diharapkan Puskesmas dapat meningkatkan pelayanan kepada anak demam, serta memberikan penyuluhan kepada ibu untuk meningkatkan pemahamanan ibu tentang penatalaksanaan demam anak.
ANALISIS SWOT DALAM PENENTUAN BOBOT KRITERIA PADA PEMILIHAN STRATEGI PEMASARAN MENGGUNAKAN ANALYTIC NETWORK PROCESS
Authors: Utsalina Dwi Safiroh , Primandari Liduina Asih 
Published: June 2023

Sistem penunjang keputusan (SPK) memberikan rekomendasi kepada para pemangku kepentingan dalam membuat keputusan, guna menjalankan fungsi manajemen organisasi(perguruan tinggi). Pemasaran dalam perguruan tinggi menjalankan salah satu fungsi utama manajemen yaitu Planning. Planning ditempuh untuk memenangkan persaingan (untuk mendapatkan mahasiswa baru). Peningkatan jumlah mahasiswa baru dapat diperoleh dengan berbagai strategi pemasaran sebagai alternatif. Namun strategi pemasaran yang direncanakan tidak semua dilaksanakan pada satu periode penerimaan mahasiswa, untuk itu diperlukan pendekatan SPK yang didukung oleh beberapa kriteria sehingga diharapkan dapat menghindarkan para pemangku kepentingan dalam menentukan strategi pemasaran yang subyektif. Berdasarkan kriteria yang telah ditentukan perlu menentukan bobot pada masing-masing kriteria, umumnya terdapat beberapa cara untuk menentukan bobot kriteria. Analisis SWOT sebagai salah satu pendekatan yang digunakan untuk mendapatkan bobot derajat kepentingan pada kriteria terhadap alternatif. Dengan menggunakan SWOT dapat memberi gambaran yang jelas akan organisasi, kemudian nilai bobot yang diperolehnya dihitung dengan ANP. Metode ANP sebagai metode MCDM dengan konstruksi jaringan, menyediakan ketergantungan antara komponen SPK, dari kriteria terhadap sub-kriteria, ketergantungan dari kriteria terhadap alternatif dan sebaliknya. Dimulai dengan penentuan tujuan, kriteria-sub kriteria, alternatif, bobot kepentingan masing-masing komponen, bobot kriteria dituliskan dalam pairwise comparison sehingga menghasilkan supermatrix. Hasil dari penelitian menunjukkan bahwa dengan SWOT, proses penentuan bobot kriteria dapat lebih efektif.
PENENTUAN SISWA BERPRESTASI KELAS BAHASA DI SMA “EFG” MENGGUNAKAN METODE EDAS
Authors: Afandhi Andra Rizky , Rakhma Devi Putri Aisyiyah , Rosyid Harunur 
Published: June 2023

Siswa berprestasi merupakan salah satu acuan dalam tingkat keberhasilan pada Sekolah Menengah Atas. Siswa yang berprestasi pada Kelas Bahasa Di SMA “EFG” Kabupaten Gresik akan mendapatkan sebuah penghargaan berupa uang pendanaan. Pada kelas Bahasa di SMA pada pada Kabupaten Gresik disetiap tahunnya akan terdapat siswa berprestasi dan siswa tersebut akan mendapatkan penghargaan dari Sekolah tersebut. Dalam menentukan siswa berprestasi SMA “EFG” selama ini hanya mengandalkan nilai dari raport siswa dan nilai ujian siswa berdasarkan seluruh mata pelajaran yang ada pada SMA, yang dimana menjadi permasalahan dalam penentuan siswa berprestasi pada setiap tahunnya, Contohnya seperti apabila terdapat siswa yang memiliki nilai pelajaran umum tinggi siswa tersebut dapat menjadi siswa berprestasi, pada kenyataannya siswa yang memiliki nilai pelajaran khusus jurusan Bahasa yang seharusnya menjadi siswa berprestasi. Metode EDAS digunakan dalam penentuan siswa berprestasi dengan menggunakan kriteria yang telah ditentukan. Berdasarkan perhitungan perangkingan akhir menggunakan metode EDAS didapatkan hasil perangkingan siswa berprestasi pada kelas Bahasa di SMA “EFG” Kabupaten Gresik yaitu kode SW40 dengan nilai Akhir AS sebesar 0,50. Metode EDAS hanya memiliki nilai tingkat akurasi 30% sehingga hasil dari penelitian menunjukkan bahwa hanya beberapa siswa yang dapat dikategorikan sebagai siswa berprestasi. proses penentuan siswa berprestasi pada penelitian ini kurang valid dikarenakan bobot kriteria yang digunakan kurang efektif karena masih perlu ditambahkan nilai bobot pada kriteria sehingga pada penggunaan metode EDAS dalam penentuan Siswa Berprestasi akan menghasilkan tingkat akurasi yang lebih tinggi.
The CHAIN WRITING METHOD IN LEARNING WRITING FOR INFORMATION TECHNOLOGY FACULTY STUDENTS: The Effectiveness
Authors: Primasari Yusniarsi , Puspita Sari Hesty , Sutanti Nita 
Published: June 2023

This study purposes in determining the effectiveness of students writing ability on descriptive text being taught using the Chain Writing Method for the B class of Informatics Engineering Study Program Balitar Islamic University 2020/2021 academic year. This research is an experimental research, which uses the chain writing method to find out its effectiveness from student learning outcomes. The population of this study were first semester students of Informatics Engineering Study program which consisted of 21 students as a sample. The researchers applied one group pretest posttest. The sampling technique is random sampling. The method used is a quasi-experimental design. The pretest result done by Informatics Engineering students shown the average was 44.19%. The pre-test was conducted by researcher in March 2020. Then it can be concluded that their Writing Descriptive text ability are not good enough. The results of data analysis, known that the chain writing method is more effectively used in learning to write descriptive text for B class of Informatics Engineering students. It has significance difference in mean of determining by précising statistics of dependent T-test. From the calculating result of the t-test found that the t-value obtained was 5,959, while the required critical t-value at p> .05, the level of significance of the two tailed test is 2.086 (df = 20), p> .01 the two tailed significant level of test was 2.845 (df = 20). The data results of this research indicates that there is a significance difference in pretest and posttest score result. This proves that the chain writing method is effective method in learning the descriptive texts for the informatics engineering class in the 2020/2021 academic year.
INTEGRATED FLASHCARD AND LUDO VOCABULARY LEARNING GAME TO INCREASE VOCABULARY ACHIEVEMENT OF THE FIRST GRADE OF JUNIOR HIGH SCHOOL: RESEARCH AND DEVELOPMENT
Authors: Badriyatin. F Endang , Supriyono  , Aini Miza Rahmatika 
Published: June 2023

This research was aimed to establish, to find out the effectiveness, and to know the teacher’s and student’s responses of Flash Ludo Game as a vocabulary learning media for first grade students of Junior High School. The researcher was applied Research and Development (R&D) design whis is adapted from Sugiyono. It consisted of five phases, they were: data collection and finding potentials and problems, design and development, expert validation and revision, product trial, and final product. The final product of the model consisted of three kinds of flashcards, a set of ludo game, and three kinds of guidebooks. The result of design and development showed that the model was very valid, the average of material and media experts was 92.5%. The product trial was done with 20 seventh grade students as participants. The one-group pre-post test showed that before using the model, the average student’s score was (45.80) and after using the model, it reached (84.05). From the t-test analysis, the researcher found that the sig (2.tailed) value was .000, it showed that the Sig. value (2-tailed) <0.05, in means that was a significant difference between pre-test and post-test. The result of teacher’s and student’s responses showed that the model was very proper, with the average result was 94%. The vocabulary learning media was effective and improve student’s vocabulary achievement for the first grade students of Junior High School.
GAMBARAN PEMBERIAN INFORMASI OBAT ANALGETIK SEBAGAI UPAYA SWAMEDIKASI DI APOTEK-APOTEK KECAMATAN TALANG KELAPA BANYUASIN
Authors: Tedi Tedi , Astuti Ratnaningsih Dewi , Sari Bella Maya 
Published: June 2023

Latar Belakang: Tingginya persentase upaya masyarakat untuk mengobati diri sendiri serta kebutuhan informasi obat yang tinggi, maka pemberian informasi obat harus diberikan secara tepat oleh tenaga kefarmasian untuk mencegah medication error pada masyarakat. Tidak hanya pada obat yang diresepkan, tetapi juga pada obat bebas. Penelitian ini bertujuan untuk menggambarkan ketepatan pemberian informasi obat analgetik bebas sebagai upaya swamedikasi di apotek-apotek Kecamatan Talang Kelapa
Metode: Jenis penelitian ini adalah penelitian observasi dengan pendekatan deskriptif dengan jumlah sampel 16 orang. Pengambilan data dilakukan dengan metode pasien simulasi yang melakukan pembelian obat analgetik di apotek sesuai skenario yang disiapkan.
Hasil: Dari sebelas aspek ketepatan informasi obat analgetik bebas yang dilakukan oleh tenaga kefarmasian di delapan apotek kecamatan Talang Kelapa. Informasi yang paling tepat diberikan yaitu cara penyimpanan obat dan cara memperlakukan obat yang masih sisa sebesar 100%. Informasi lainnya yang memiliki penilaian sangat baik yaitu lama penggunaan obat dan cara membedakan obat yang masih baik dan sudah rusak sebesar 87,5%, informasi khasiat obat dan cara pemakaian obat sebesar 81,3%. Informasi dengan ketepatan baik antara lain waktu pemakaian obat (68,7%), kontraindikasi (62,5%), dosis (62,5%), efek samping (56,3%). Sedangkan edukasi mengenai penyakit pasien menjadi informasi paling rendah ketepatannya dengan persentase 37,5% dengan penilaian cukup baik.
Kesimpulan: Secara keseluruhan ketepatan pemberian informasi obat analgetik bebas sebagai upaya swamedikasi di apotek-apotek Kecamatan Talang Kelapa sudah dinilai baik. Hanya saja tenaga kefarmasian yang ada kebanyakan bersikap pasif, sehingga dibutuhkan keaktifan pasien simulasi dalam mendapatkan informasi agar bisa menentuan tepat atau tidaknya sebuah informasi.