bluuebunny/crossref_metadata_2025_split huggingface dataset:
Low Complexity Enhancement VVC Encoder for Vehicular Networks
Authors: Jiang Xiantao , Li Wei , Song Tian 
Published: July 2023

Abstract
In intelligent transportation systems, real-time video streaming via vehicle networks has been seen as a vital difficulty. The goal of this paper is to decrease the computational complexity of the Versatile Video Coding (VVC) encoder for VANETs. In this paper, a low complexity enhancement VVC encoder is designed for vehicular communication. First, a fast coding unit (CU) partitioning scheme based on CU texture features is proposed in VVC, which aims to decide the final type of CU partition by calculating CU texture complexity and gray level co-occurrence matrix (GLCM). Second, to reduce the number of candidate prediction mode types in advance, a fast chroma intra prediction mode optimization technique based on CU texture complexity aims to combine intra prediction mode features. Moreover, the simulation outcomes demonstrate that the overall approach may substantially cut down on encoding time, while the loss of coding efficiency is reasonably low. The encoding time can be cut by up to 53.29\% when compared to the VVC reference model, although the average BD-rate is only raised by 1.26\%. The suggested VVC encoder is also hardware-friendly and has a minimal level of complexity for video encoders seen in connected vehicle applications.
Bgnba-oco Based Privacy Preserving Attribute Based Access Control With Data Duplication for Secure Storage in Cloud
Authors: Pavithra M. , PRAKASH M , VENNILA V 
Published: July 2023

Abstract
Cloud computing technology offers flexible and expedient services which carry a variety of profits for both societies as well as individuals. In the epoch of data explosion, customers and business establishments require to store enormous data. The exception of cloud service advantages, data confidentiality becomes a challenging aspect to be covered as far as executing data access control. The implementation of Attribute-based Encryption in a Cloud Computing (CC) environment solves the demanding topic of outsourced data enabling fine-grained and pliable access control. In this work, a method called Boneh Goh Nissim Bilinear Attribute-based Optimal Cache Oblivious (BGNBA-OCO) access control and secure de-duplication for data storage in cloud computing is proposed. First, Boneh Goh Nissim Privacy Preserving Revocable Attribute-based Encryption is designed that reinforces attribute revocation and avert the discharge of sensitive information. Moreover, to prevent disclosure of access patterns Optimal Cache Oblivious algorithm is employed to hide the access patterns in cloud storage using rand pattern matching. It also supports updating both encrypted data and access control policies to minimize communication and computation overhead of data duplication and encryption processes concurrently. In this way, secure data sharing is performed to achieve higher data confidentiality and integrity. The analyzed results indicate that the BGNBA-OCO method offers an efficient solution in terms of achieving higher data confidentiality, and integrity, and minimizing the communication as well as computation overhead than the conventional techniques.
The Evolution of ‘Riskscapes’: 100 years of climate change and mountaineering activity in the Lake Louise area of the Canadian Rockies
Authors: Hanly Katherine , McDowell Graham 
Published: July 2023

Abstract
Climate change is contributing to the rapid warming of mountain environments, resulting in glacial retreat, diminished snowpacks, and permafrost thaw. These changes modify conditions and increase objective hazard on mountaineering routes, threatening the safety and wellbeing of mountaineers. In response, this study used a mixed-methods approach that combines statistical climatological analysis with archival-content analysis to examine the relationship between climate change, route conditions, hazards, and adaptations reported by climbers in the Abbot Pass area of Banff National Park (Canada). Results revealed an increase in temperature and decrease in total precipitation, corresponding with considerable changes in climbing conditions and increases in objective hazards on approach and popular climbing routes in the area. These changes can be classified based on the original character of the route and their climate-driven trajectory, creating a novel typology that informs how mountaineers adapt (i.e., spatial vs. temporal substitution). This typology has substantial implications for mountaineers as it could enhance their decision-making processes by allowing them to proactively develop plans that reduce exposure to objective hazards and capitalize on climate-related opportunities. However, our findings also highlight the potential inevitability of mountaineers encountering hard biophysical limits to adaptation, resulting in forced transformations and significant loss and damages. While focused on a Canadian context, the findings and methodologies developed herein are relevant to other mountain geographies, where climate change is rapidly transforming environments frequented by mountaineers and represents a call to action for more research in field of climate change, adaptation, and mountaineering.
Associations Between Velamentous or Marginal Cord Insertion and Risk of Adverse Perinatal Outcomes in Twin Pregnancies: A Retrospective Cohort Study
Authors: Wen Li , Zhong Qimei , Mei Lingwei , Gao Li , Lan Xia , Xiong Jing , Luo Shujuan , Wang Lan 
Published: July 2023

Abstract
Background
velamentous cord insertion (VCI) and marginal cord insertion (MCI) are well-known risk factors for adverse perinatal outcomes in singleton pregnancies. However, the potential links between VCI or MCI and perinatal outcomes in twin pregnancies have yet to be systematically evaluated. This study aimed to investigate the relationships between VCI or MCI and perinatal outcomes, neonatal outcomes in twin pregnancies.
Methods
This was a retrospective single-center cohort study that included women with twin pregnancies and gave birth in a tertiary hospital in Southwest, China between January 2017 and December 2022. VCI and MCI were identified by abdominal ultrasound and checked after placenta delivery. Logistic regression models, multinomial logit regression models and generalized estimation equation models were used to evaluated the association between VCI or MCI and perinatal outcomes.
Results
3682 twin pregnancies were included, 100 (2.7%) pregnancies with VCI and 149 (4.0%) pregnancies with MCI. Compared to pregnancies with normal cord insertion, pregnancies with VCI were associated with an increased risk of preterm delivery 32–34 weeks both in monochorionic twins (aRRR 2.94, 95% CI 1.03–8.39) and dichorionic twins (aRRR 2.55, 95% CI 1.19–5.46), while pregnancies with MCI were not associated with preterm delivery. Pregnancies with VCI were associated with higher incidence of placental previa (aOR 6.36, 95% CI 1.92–21.04) in monochorionic twins and placental accreta in dichorionic twins (aOR 1.85, 95% CI 1.06–3.23). Pregnancies with MCI were associated with increased risk of preeclampsia (aOR 3.07, 95% CI 1.49–6.32), intertwin birthweight discordance ≥ 20% (aOR 2.40, 95% CI 1.08–5.60) and selective fetal growth restriction (aOR 2.46, 95% CI 1.08–5.60) in monochorionic twins and small-for-gestational age neonates (aOR 1.97, 95% CI 1.24–3.14) in dichorionic twins.
Conclusions
Twin pregnancies with VCI were associated with an increased risk of preterm delivery irrespective of chorionicity, whereas twin pregnancies with MCI were associated with an increased risk of preeclampsia, significant intertwin birthweight discordance in monochorionic twins and small-for-gestational age neonates in dichorionic twins.
Research on Capability Maturity Evaluation of Pharmacy Intravenous Admixture Services using Pharmacy Intravenous Admixture Services Data Reporting and Analysis Platform
Authors: Tian Shaowu , Xie Genyu , Xu Fan , Zhang Jun 
Published: July 2023

Abstract
Purpose: To enhance the capabilities of Pharmacy Intravenous Admixture Services (PIVAS) in ensuring the safety and appropriate utilization of intravenous medications in medical institutions.
Methods: The Regional Pharmacy Intravenous Admixture Services Data Reporting and Analysis Platform (RPDRAP) was established in 2018. This platform comprises a data collection system and a data analysis system. The data collection system consists of 67 data items and utilizes network-based data collection. The collected data were analyzed using a model with 20 indicators within the data analysis system. Fifteen PIVAS participated in the platform's application evaluation.
Results: The study revealed significant differences in PIVAS total score, supervisors, and workload between 2020 and 2022. The platform's application results demonstrated improvements in personnel management, work efficiency, and infection control within these PIVAS. Although statistical significance was observed in only 8 out of the 25 items, most of the scores showed an increase, with a small portion remaining unchanged and no decline in scores.
Conclusions: This platform can be recommended for PIVAS homogeneous and regional efficient management. The use of this platform not only improves the quality control ability of PIVAS but also enables the management department to quickly grasp the current situation and characteristics of each PIVAS through standardized data collection and analysis.
Understanding Lactation Policies and Resources Across a University System: Survey &amp; Document Review
Authors: Loedding Emily H. , Donepudi Sritha , Padilla Heather M. 
Published: July 2023

Abstract
Background
Add a sentence here about breastfeeding – establishing problem. In the U.S., working women often return to work within 8–12 weeks of giving birth, therefore, it is critical that workplaces provide support for female employees combining breastfeeding and work. The Affordable Care Act requires any organization with more than 50 employees to provide a space other than a restroom for women to express breastmilk and a reasonable amount of time during the workday for women to express breastmilk. States and worksites differ in the implementation of ACA requirements and may or may not provide additional supports for female employees combining breastfeeding and work. The purpose of this study was to conduct an analysis of 26 institutions within a state university system to evaluate the differences in breastfeeding policies and resources available on each campus.
Methods
Survey data was collected from well-being liaisons in the human resources departments at each institution. In addition, we conducted a document review of policies and online materials at each institution. We used univariate statistics to summarize survey results while a thematic analysis was used to analyze institutional resources available on websites and in policies provided by the liaisons.
Results
A total of 18 (65.3%) liaisons participated in the study and revealed an overall lack of familiarity with the policies in place and inconsistencies in the resources offered to breastfeeding employees across the university system. Only half of the participating liaisons reported a formal breastfeeding policy was in place on their campus. From the document review six major themes were identified: placing the burden on female employees, describing pregnancy or postpartum as “disability,” having a university specific policy, inclusion of break times for breastfeeding, supervisor responsibility, and information on lactation policies.
Conclusion
The review of each institutions online resources confirmed the survey findings and highlighted the burden placed on female employees to discover the available resources and advocate for their needs. This paper provides insight into how institutions support breastfeeding employees and provides implications on strategies to develop policies at universities to improve breastfeeding access for working mothers.
Analysis of Proton Radiation-induced Effects on Polymer-based Relative Humidity Sensor
Authors: Kapić Amar , Tsirou Andromachi , Verdini Piero Giorgio , Carrara Sandro 
Published: July 2023

Abstract
Cooling at subzero temperatures and the subsequent monitoring of humidity in the modern Si-based high-energy physics detectors are indispensable but challenging due to space, radiation and magnetic field issues. In this study, a group of relative humidity sensors have been tested for operation reaching high irradiation doses adequate to the inner sub-detectors during the HL-LHC operation. The sensors were exposed to the 24 GeV/s proton beam for a period of 33 days reaching the fluence of 3 x 1016 protons/cm2. The test has demonstrated sensors radiation tolerance at high doses and their ability to provide valid alerts to the detector control and safety systems in the event of any changes in humidity.
The irradiation was conducted in a temperature- and humidity-controlled environment. Tested samples were placed in a specially designed cold box able to guarantee an ambient temperature of -20 oC. Throughout the entire test, the compressed dry air was used to keep low humidity levels (around 0 %rh) inside the cold box, and a 100 ppm pre-calibrated gas mixture was used to test the sensors responsiveness before and after the irradiation process. Additionally, an on-purpose designed signal conditioning unit was used to compensate for the cable parasitic effects.
Serine to proline mutation at position 341 of MYOC impairs trabecular meshwork function by causing autophagy deregulation
Authors: Zhang Jingxue , Yan Xuejing , Wu Shen , Liu Qian , Cheng Ying , Teng Yufei , Ren Tianmin , Wang Ningli 
Published: July 2023

Abstract
Glaucoma is a highly heritable disease and myocilin was the first identified causal gene and most common pathogenic gene in glaucoma. Serine to proline mutation at position 341 of myocilin (MYOCS341P) is associated with severe glaucoma phenotypes in a five generation of primary open angle glaucoma family. But the underlying mechanisms is under explored. Here, we established MYOCS341P transgenic mouse model and characterized the glaucoma phenotypes. Further, we systematically explored the differences in function between wild-type and MYOCS341P by immunoprecipitation followed by mass spectrometry and RNA-seq analyses. We found that MYOCS341P transgenic mouse exhibit glaucoma phenotypes, characterized by reduced aqueous humor outflow, elevated intraocular pressure, decreased trabecular meshwork (TM) cells number, narrowed Schlemm’s canal, retinal ganglion cell loss, and visual impairment. Mechanistically, secretion incompetent MYOCS341P accumulated in the endoplasmic reticulum (ER), induced ER stress, and causes deregulation of autophagy, thereby promoting TM cell death. We describe an effective transgenic model for mechanistic studies and screening of therapeutic targets. And our data generated from high-throughput analyses help to elucidate the mechanism underlying mutant MYOC-related glaucoma.
Pearl farming micro-nanoplastics affect both oyster physiology and pearl quality
Authors: Gardon Tony , Luyer Jérémy Le , Moullac Gilles Le , Soyez Claude , Lagarde Fabienne , Dehaut Alexandre , Paul-Pont Ika , Huvet Arnaud 
Published: July 2023

Abstract
The widespread contamination of pearl farming lagoons in French Polynesia by microplastics has led to questions about risks for the pearl industry. The aim of this study was to test the effects of micro-nanoplastics (MNPs) on the pearl oyster (Pinctada margaritifera) over a 5-month pearl production cycle. MNPs were produced from plastic pearl farming gear and used at concentrations that oysters may encounter in lagoons. MNP exposure led to the alteration of energy metabolism, mostly driven by a lower assimilation efficiency of microalgae, with modulation of gene expression patterns. Pearl biomineralization was also impacted by thinner aragonite crystals, with harvest marked by the presence of abnormal biomineral concretions, called keshi pearls. These experimental results demonstrated that MNPs threaten pearl oyster biology, with potential detrimental effects on pearl quality. Ecological approaches are now required to test the holistic impact of MNPs on population maintenance and sustainability in the Polynesian pearl industry in the context of the exposome and global change.
Teaser
Exposure to pearl farming micro-nanoplastics impact oyster metabolism and harvest quality over a 5-month pearl production cycle.
The First Two Years of Virginia’s Substantial Risk Order
Authors: Geller Lisa , McConnell Natalie , Zelle Heather , Roskam Kelly , Haas Lori , Bonnie Richard 
Published: July 2023

Abstract
Background.
Gun violence is a public health crisis in the United States. Extreme risk protection orders, called substantial risk orders in Virginia, are a prevention tool that temporarily remove firearms from individuals at risk of harm to self or others. To date, no peer-reviewed papers have explored the use of substantial risk orders in Virginia.
Methods.
We reviewed risk order data from Virginia from July 1, 2020, to June 30, 2022. The risk order data included in this study was obtained from the Virginia State Police Criminal Justice Information Services Division. We calculated descriptive statistics for the number and type of risk order (in total and by locality), demographic variables (sex, race, and age), and incidence rates.
Results.
There were 281 emergency risk orders and 173 final risk orders between July 2020 and June 2022. Most risk order respondents were white males in their mid-to-late 30s. Fifty-eight of the 133 localities in our study reported at least one risk order. However, the ten localities that issued the greatest numbers of risk orders issued 73% of all emergency risk orders and 67.6% of all final risk orders. Across the 58 localities in our dataset, the average incidence of emergency risk orders was 3 per 100,000 people per year and the average incidence of final risk orders was 2 per 100,000 people per year.
Conclusions.
The risk order is a relatively new law in Virginia. Though many of the descriptive statistics we calculated in Virginia are similar to what we see in other states with this law, more time is needed to examine its impact on gun violence.
Emerging Combination Strategy: FANCI Inhibition Induces PARP1 Redistribution to Enhance Efficacy of PARP Inhibitors in Breast Cancer
Authors: Huang Yu-zhou , Sang Ming-Yi , Xi Pei-wen , Xu Ruo-xi , Cai Meng-Yuan , Wang Zi-Wen , Zhao Jian-Yi , Li Yi-Han , Yin Peng , Wei Ji-Fu , Ding Qiang 
Published: July 2023

Abstract
Background
While PARP inhibitors have made advancements in the treatment of breast cancer, challenges such as chemotherapy resistance and limited application persist. FANCI, a DNA repair protein associated with breast cancer development, represents a potential target for novel combination therapeutic strategies. However, the role of FANCI in breast cancer and its impact on the efficacy of PARP inhibitors require further investigation.
Methods
In this study, we analyzed FANCI expression in breast cancer tissues and cell lines, and its correlation with clinical parameters and patient prognosis. Lentiviral vectors were utilized and functional assays were performed to evaluate the effects of FANCI modulation on breast cancer cell growth and metastasis. Co-immunoprecipitation assays and protein interaction analysis were conducted to identify the interaction between FANCI and PARP1 and determine the specific binding region. The functionality and nuclear distribution of PARP1 were assessed upon FANCI modulation. Finally, the sensitivity of breast cancer cells to the PARP inhibitor talazoparib upon FANCI knockdown was evaluated in vitro and in vivo.
Results
Our findings demonstrated that FANCI was overexpressed in breast cancer and associated with poor prognosis. FANCI significantly promoted breast cancer cell proliferation both in vitro and in vivo. We identified the interaction between FANCI and PARP1, specifically at the FANCI HD2 binding site. FANCI inhibition led to reduced nuclear localization of PARP1 and decreased PARP1 activity. Importantly, combination treatment with FANCI knockdown and talazoparib significantly inhibited cancer growth in vitro and in vivo. Additionally, we found that the CDK4/6 inhibitor palbociclib, which effectively suppresses FANCI protein expression, exhibited a robust synergistic effect with talazoparib both in vitro and in vivo.
Conclusion
FANCI is a novel therapeutic target for breast cancer. Inhibition of FANCI regulates PARP1 redistribution and activity, making cells more responsive to PARP inhibitors. This combination therapeutic strategy shows potential in enhancing the effectiveness of PARP inhibitors for breast cancer treatment, regardless of BRCA mutations.
Full-band Electromagnetic Stealth
Authors: Su Jian Xun , Qu Meijun , Yu Hang , Li Wen Yu , Yin Hong Cheng , Cui Tie Jun 
Published: July 2023

Abstract
The existing technologies to reduce radar cross sections (RCSs) face numerous challenges in bandwidth expansion, and hence they have a long way to achieve full-band stealth. Additionally, the control mechanism of RCS reduction level is deficient. Here, we explore the root of problem to cause the bandwidth blind zones and propose a mathematical model to establish a mapping relation between the array factor (AF) in spatial domain and the RCS reduction in frequency domain. The mathematical model of full-band stealth for general oblique incidence is also constructed, which guides to design a diffuse artificial meta-structure (AMS) to validate the proposed model. Then we build a mathematical model based on the Chebyshev polynomial for RCS reductions with RdB equal-amplitude in controlling the scattering fields. As proof of principle, a diffuse AMS is designed, fabricated, and measured to reach the RCS reductions with preseted 21 dB equal-amplitude. The simulated and measured results are in good agreement, proving that the proposed theoretical models provide a cornerstone of the future advanced stealth technologies.