bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diagnosis and management of ureterovaginal fistula in a resource limited setting: a 12 years’ experience at four fistula surgery centers in Uganda
Authors: Kajabwangu Rogers , Geissbüehler Verena , Tibaijuka Leevan , Byamukama Onesmus , Kalyebara Paul Kato , Ainomugisha Brenda , Margolis Thomas , Lukabwe Henry , Njagi Joseph , Lugobe Henry Mark , Kayondo Musa 
Published: April 2023

Abstract
Background: Ureterovaginal fistulae usually follow iatrogenic injury to the ureter during pelvic surgery. This manifests as urine incontinence and results in serious psychosocial effects to the women. Ureterovaginal fistulae unlike vesicovaginal fistulae present challenges in diagnosis and management especially in resource constrained settings.
Objective: To describe the magnitude, aetiology, diagnosis, management and outcomes of ureterovaginal fistula at four fistula surgery centres in Uganda over a twelve-year period.
Methods: A retrospective review of charts for women who had fistula repair at four regional fistula repair centres in Uganda from 2010 to 2021 was conducted. The diagnosis of ureterovaginal fistula was made clinically using a combination of a history of leakage of urine through the vagina following a pelvic surgery, absence of visible anterior vaginal wall defect on speculum examination, a negative methylene blue dye test, and a three-swab test. All women were managed using open transvesical ureteral reimplantation with or without Boari flap. A ureteral stent and Foley catheter were left in situ for 2 weeks. The outcome of surgery (successful fistula repair with urine continence) was determined at 2 months post-surgery. This was confirmed through a vaginal speculum exam.
Results: Overall, there were 477 women who were managed for genito-urinary fistulae during the study period. Approximately 1 in every 10 women with genitourinary fistula had uretero-vaginal fistula (n=47, 9.8%). The mean age of the women with ureterovaginal fistula was 31.9 (SD ±11.8) years. Majority of the ureterovaginal fistulae (n=33, 70.7%) followed caesarean sections done at general hospitals (n=22, 46.8%) by medical officers (n=32, 68.1%). The clinical assessment method used in this study was accurate in diagnosing ureterovaginal fistula. Successful fistula repair with urine continence using the open transvesical ureteral reimplantation was achieved in 45 (95.7%) of the cases.
Conclusion: Iatrogenic ureterovaginal fistulae are common in Uganda and most follow caesarean section performed at lower-level health facilities by medical officers. In resource limited settings where advanced diagnostic techniques aren’t available or not affordable, a simple but careful step-wise clinical evaluation described in this study is effective in making a diagnosis. Open transvesical ureteral re-implantation fistula repair technique has a high successful repair rate with urine continence.
Circuit Design and Embedded Software Development of Automatic Water Seepage Meter
Authors: YUAN Junjie 
Published: April 2023

Abstract
Permeability meter plays an important role in the measurement of road seepage performance. The data deviation is easy to produce because of incorrect reading by using the manual seepage meter. Thereby, the application program based on Windows CE operating system is developed, which includes test process, data processing and battery monitoring. And the manual control, automatic delay and industry standard operation processes can be achieved by adopting the timing and event-driven modes, furthermore, it has the function of calculating standard deviation, mean value and coefficient of variation, checking out the existing data. And the recorded data can be automatically appended to the list. The software which uses the recursive median algorithm to filter the original data can monitor the dynamic change of liquid level synchronously, and can also measure the initial and final liquid level height like the manual seepage meter. It can provide a smooth curve of the seepage process. Combined with observation and data analysis, it is found that the process curve is obviously related to the phenomena of water seepage, lateral infiltration, water leakage and bubble burst, so these phenomena of water seepage process of road can be recognized through algorithm development.
Clinical application of chromosomal karyotype analysis combined with chromosomal microarray analysis in the prenatal diagnosis of pregnant women with advanced maternal age
Authors: Liu Hongyu , Deng Siyuan , He Rong , Gan jianling , Ouyang Ning 
Published: April 2023

Abstract
Background This study aimed to investigate the clinical application value of chromosome karyotype analysis and union chromosome microarray analysis (CMA) in the prenatal diagnosis of pregnant women with advanced maternal age.
Method A total of 228 pregnant women who received invasive prenatal diagnosis due to advanced age in the Medical Genetics Department of Pingxiang Maternal and Child Health Hospital, Jiangxi Province, China from January 2021 to June 2022 were retrospectively analyzed. Results of chromosome karyotype analysis and CMA were compared.
Results (1) Chromosome karyotype analysis was performed in 228 elderly pregnant women, among which 213 were normal. Abnormal karyotype was found in 15 cases. (2) Among 228 elderly pregnant women, 211 had normal CMA results and 17 had abnormal CMA results. A total of 32 abnormal cases were detected by chromosome karyotype analysis combined with CMA. (3) A total of 15 cases had abnormal karyotype, only 6 cases had abnormal CMA results, and the coincidence rate of abnormal detection rate of the two methods was 40%.(4) Chromosome inversion, translocation, chimera, and polymorphism were not abnormal in CMA.
Conclusion The above two methods had advantages and disadvantages. Karyotype analysis and microarray analysis technology can effectively improve the detection rate of abnormalities in the prenatal diagnosis of older pregnant women. This finding suggested that clinicians should comprehensively analyze various influencing factors, conduct reasonable genetic counseling, and combine the two methods of analysis to improve the detection rate of fetal abnormalities and prevent birth defects in newborns.
Issue detection and prioritization based on app reviews
Authors: de Lima Vitor Mesaque Alves , Barbosa Jacson Rodrigues , Marcacini Ricardo Marcondes 
Published: April 2023

Abstract

Opinion mining for app reviews aims to analyze people's comments on app stores to support software engineering activities, particularly software maintenance and evolution. One of the main challenges for software quality maintenance is promptly identifying emerging issues, e.g., bugs. However, due to a large amount of textual data, manually analyzing these comments is challenging, and machine learning-based methods have been used to automate opinion mining. Our objective is to minimize the time between the occurrence of the issue and its correction, providing means for the quick identification of the issue through prioritization levels. This paper introduces the automatic generation of a risk matrix from user reviews to answer the following research question: how do we prioritize and treat reviews in time so that the app is competitive and guarantees the timely maintenance and evolution of the software? We present the MApp-IDEA (Monitoring App for Issue Detection and Prioritization) method to detect issues and classify the reviews in a risk matrix with prioritization levels. We present an approach that (i) automatically collects reviews, (ii) detects issues, (iii) classifies reviews in a risk matrix, and then (iv) models the temporal dynamics of issues and risks through time series to trigger alerts. The results showed that our unsupervised issue detection approach is competitive compared to state-of-the-art supervised methods. We performed an empirical evaluation with 50 mobile applications (apps) and processed approximately 5 million reviews, where we detected 230,000 issues and classified them into priority levels using a risk matrix. We have shown that opinions extracted from user comments provide important information about the app's issues and risks. In evaluation, we found that issues detected early with our approach are associated with later fix releases by developers.
Binary to Hexadecimal decoder using Pockel’s effect guided Mach-Zehnder Interferometer (MZI)
Authors: Das Sourabh Kumar , Pahari Nirmalya 
Published: April 2023

Abstract
A novel design of binary to hexadecimal decoder using titanium diffused LiNbO3 waveguide-based electro optic (Pockel’s effect) Mach-Zehnder interferometer (MZI) has been proposed here. Decoders are digital systems which are used to convert the binary input into the desired output format. The 'Hexadecimal Numeral System' is extensively used in processing units and programming languages. ‘Hexadecimal’ numerals' key benefit is their ability to hold more numbers in less memory. The decoder accepts the binary code after processing it and changes it back into a format that output devices can use. In this paper, the conversion process is proposed using tree net architecture which is very much simpler form than any other mapping. The whole design has been simulated step wise and results are verified by OPTIBPM using beam propagation methodology (BPM). The wafer dimension of footprint of the binary to hexadecimal decoder is 0.4 cm × 800μm and hence it belongs to integrated optics.The proposed photonic decoder's short response time will be useful in commercial research for applications such as memory addressing, speech coding and decoding, line coding and decoding for digital data communication.
What factors are associated with the prognosis of Primary testicular diffuse large B-cell lymphoma? A study based on the SEER database
Authors: Yang Shujun , Chang Wei , Zhang Bin , Shang Panfeng 
Published: April 2023

Abstract

Purpose Primary testicular diffuse large B-cell lymphoma (PT-DLBCL) is a relatively rare urological tumor with a high degree of malignancy and a poor prognosis. This study aimed to investigate the prognostic risk factors for survival of patients with PT-DLBCL, and then to construct a predictive model and verify its reliability.Methods First, we selected subjects from the SEER database (2000–2018) and analyzed the survival of PT-DLBCL patients by Kaplan-Meier test. Then, we analyzed prognostic factors by Cox regression. Finally, the data from the training cohort were used to construct a prediction model and represented with a nomogram. We evaluated the nomogram using the consistency index (C-index), decision curve analysis (DCA), and the area under the subject operating characteristic curve (ROC). In addition, calibration curves were plotted to assess the agreement between the column plot model and the actual model.Results We identified five independent risk factors for patient prognosis affecting OS and CSS in patients with PT-DLBCL by univariate and multivariate analysis, including age, transversality, Ann Arbor staging, chemotherapy, and radiotherapy. According to the above factors, we constructed prognostic nomograms, and found that age contributed the most to the survival of patients with PT-DLBCL. The C-indexes for the nomogram of OS and CSS in the training cohort were 0.758 (0.716–0.799) and 0.763 (0.714–0.812), and in the validation cohort were OS and CSS 0.756 (0.697–0.815) and 0.748 (0.679–0.817).Conclusion We produced the first nomogram of PT-DLBCL, and it can be used to evaluate the CSS and OS of patients to determine the prognosis of patients.
Niche Products and the Marketplace
Authors: Kim Seongkyun 
Published: April 2023

Abstract
This paper provides a framework for analyzing the impact of a big platform's data acquisition and self-preferencing on niche firms' entry decisions with a simple two-period model. If a platform can acquire data and production cost is sufficiently low, the platform's ability to gain advantages over niche firms, which makes the platform a monopolist, influences niche firms' entry decision in several ways that depend on the size of demand given to the niche firms. Specifically, in the case of a niche firm having a small demand size, the related abilities of the platform facilitate the entry of niche firms, which is often impossible without data acquisition and self-preferencing exposures enabled by the platform. On the other hand, those abilities of the platform are a threat to the niche firms with intermediate-size demand, and thus negatively influence their entry decision. In terms of welfare, we find that those abilities of the platform can improve the consumer's surplus and total welfare by reducing the platform's common optimal referral rate for niche products, although they can harm the net profit of niche firms.
JEL classification: D82, L12, L41
Potential risk resulting from the influence of static magnetic field upon living organisms. Numerically simulated effects of the static magnetic field upon biologically important amino acids
Authors: Ciesielski Wojciech , Kołoczek Henryk , Oszczęda Zdzisław , Soroka Jacek A. , Tomasik Piotr 
Published: April 2023

Abstract
Background An attempt to recognize the effects of a static magnetic field (SMF) of varying flux density on flora and fauna is performed. It involves studies on the influence of SMF upon molecules of selected 19 proteinogenic amino acids essential for functioning flora and fauna.Methods Computations of the effect of real SMF 0.0, 0.1, 1, 10, and 100 AMFU (Arbitrary Magnetic Field Unit; here 1AMFU ≥ 1000 T) flux density were performed in silico (computer vacuum) involving advanced computational methods.Results The static magnetic field (SMF) decreased the stability of the amino acid molecules. This effect depended on the position of the molecule with respect to the direction of the SMF of the Cartesian system. An increase in the value of heat of formation was accompanied by an increase in the dipole moment.of the molecules It was an effect of deformations of the molecules. Solely the cysteine and tryptophan molecules suffered radical transformation at 100 AMFU.Conclusions SMF even of the lowest strength, a 0.1 AMFU flux density influences the biological role of amino acids. This effect is generated chiefly due to the changes in the electron density and a decrease in the binding coherence of the electron pair in the external SMF around the atoms of the carboxylic and amino groups.
The three-tube method via precise interventional placement for esophagojejunal anastomotic fistula after gastrectomy: A single center experience Running Title：Three-tube method for esophagojejunal anastomotic fistula
Authors: ding xiaolong , Zhang Chenchen , Li Xiaobing , Liu Tao , Ma Yaozhen , Yin Meipan , Li Chunxia , Zhou Gang , Wu Gang 
Published: April 2023

Abstract
Background Esophagojejunal anastomotic leakage is a serious complication after total gastrectomy. This study evaluated the safety and efficacy of transnasal placement of drainage tube, jejunal decompression tube, and jejunal nutrition tube under fluoroscopy for treatment of esophagojejunal anastomotic fistula after gastrectomy in gastric cancer patients.Methods Retrospective review of patients with esophagojejunal anastomotic fistula treated with transnasal placement of abscess drainage tube, decompression tube, and jejunal nutrition tube under fluoroscopy. Fistula healing time, patient survival, and Eastern Cooperative Oncology Group (ECOG) performance status before and after treatment were evaluated.Results Sixty-four patients were included in the study. Insertion of the transnasal abscess drainage tube, decompression tube, and jejunal nutrition tube was successful on the first attempt in all patients. Simple transnasal drainage was used in 35patients, simple percutaneous abscess drainage was used in 13 patients, and transnasal drainage plus percutaneous abscess drainage in 16patients. After placement of the tube, the mean volume of drainage was 180ml (10–850 mL); the amount steadily decreased from then on. The clinical treatment success rate is 84.3%(54/64). Median time to fistula healing was 58 days (7 days to 357 days).Conclusions Transnasal insertion of transnasal abscess drainage tube, jejunal decompression tube, and jejunal nutrition tube under fluoroscopy appears to be a simple, minimally invasive, effective, and safe method for treating esophagojejunal anastomotic fistula after gastrectomy.
Disparities in Utilization of Mammogram Screening and Incidence of Postmenopausal Metastatic Breast Cancer in Asian American Women
Authors: Reddy Megan , Liao Cheng-I , Aliabadi Arya , Johnson Caitlin R. , Kapp Daniel S. , Chan John K. 
Published: April 2023

Abstract
Background The incidence of metastatic breast cancer is rising, but few studies have analyzed Asian American women with a focus on screening and obesity rates.Methods Data from the U.S. Cancer Statistics were examined for trends and incidence rates of breast cancer. Using the Center for Disease Control data mammogram compliance and obesity rates in Asian women were analyzed.Results Over our 18-year study period, the incidence of postmenopausal metastatic breast cancer increased by 2.19% annually in Asian women compared to only 1.03% in White women. Asians also had higher rates of mammogram non-compliance compared to other racial groups. Of Asians, the rates of obesity in postmenopausal women were highest in those aged 65–74 years.Conclusions Compared to other races, Asians have the highest increase in the incidence of metastatic breast cancer with lower rates of screening mammograms. Further research is needed to better understand these disparities.
Use of animal origin protein concentrates in bread baking
Authors: Shabunina Maria , Andreeva Anastasiya , Pavlova Anastasia 
Published: April 2023

Protein deficiency in the human diet is a widespread problem that affects all body systems. Nutrition adjustment appears to be one of the most effective ways to prevent this problem. This study was aimed at investigating the possibilities of using animal origin protein concentrates in bread baking industry.
Study objects included five breads: one control and four samples containing protein concentrates. The test wheat bread samples contained 7, 9, and 11% of milk protein concentrate and 7% of whey protein concentrate to the mass of flour in the dough. Rheological parameters of the dough were obtained using an alveograph and a farinograph. The specific volume and sensory characteristics of the baked products as well as crumb deformation were evaluated. The nutritional value of two samples – control and with 9% of milk protein concentrate addition – was determined by calculation.
Whey protein concentrate had a negative influence on the dough rheology. Low water binding capacity and specific volume as well as hard crumb make the usage of this product in bread baking unacceptable. The palatability test showed that bread supplemented with 9% of milk protein concentrate had the best sensory characteristics, compared to control and other test samples (with 7 and 11% of this concentrate). The predicted protein content was equal to 11.6 g/100 g that is 35% higher than in the control sample. Consequently, milk protein concentrate has a potential to improve biological value of the bread that can be further helpful to prevent the protein deficiency.
Milk protein concentrate can be successfully used in the bread making process as an ingredient to correct the nutritional and biological value of baked products.
Plant extracts and essential oils in the dairy industry: A review
Authors: Abd El-Aziz Mahmoud , Salama Heba H. , Sayed Rehab S. 
Published: April 2023

Plants have been used as food additives worldwide to enhance the sensory qualities of foods and extend their shelf life by reducing or eliminating foodborne pathogens. They also serve as therapeutic agents due to their beneficial effects on human health through their anti-cancerous, anti-inflammatory, antioxidant, and immune-modulatory properties.
Plants can be added to food as a dry powder, grated material, paste, juice, or as an extract that can be produced by a variety of methods. Plant extracts and essential oils are concentrated sources of bioactive phytochemicals that can be added to food in small amounts in a variety of forms. These forms include liquid, semi-solid, or dry powder for easy and uniform diffusion. Encapsulation can protect bioactive compounds from temperature, moisture, oxidation, and light, as well as allow for controlling the release of the encapsulated ingredients. Nanoemulsions can enhance the bioactivity of active components.
This review explains how plant extracts and essential oils are used in the dairy industry as antimicrobial materials, analyzing their impact on starter bacteria; as natural antioxidants to prevent the development of off-flavors and increase shelf life; and as technological auxiliaries, like milk-clotting enzymes, stabilizers, and flavoring agents. Therefore, plant extracts and essential oils are a better choice for the dairy industry than plants or their parts due to a wide range of applications, homogeneous dispersion, and ability to control the concentration of the bioactive ingredients and enhance their efficiency.
Water environment characteristics and control countermeasures of typical hilly cities in Southeast China
Authors: You Aiju , Hua Lei , Hu Jingwen , Wang Ziming 
Published: April 2023

Abstract

Due to population growth and economic development, problems such as uneven distribution of freshwater resources and degradation of water quality are becoming increasingly prominent. Many measures have been adopted to address water resources issues; however, few studies have focused on specific changes in water quality after policy implementation. In this study, Yiwu City, Zhejiang Province, a typical hilly city with a well-developed water system, was selected to analyze the changes in water quality. By analyzing the rainfall series and hydrology characteristics, and water quality characteristics, this paper revealed the water environment characteristics and put forward some suggestions for water management in hilly cities. Results showed that the historical rainfall time distribution is uneven, and the water environment capacity of urban inland rivers exhibits strong variability in Yiwu City. The contents of ammonia nitrogen (NH3-N) and total phosphorus (TP) decreased significantly since the policy implementation of ‘Five water cohabitation’. Urban rivers presented regional pollution and surface source pollution characteristics, and the water quality fluctuated significantly with the increase in rainfall. At the same time, the study confirmed that scientific water replenishment measures can effectively improve water quality, providing reference ideas for the protection and management of China's urban water environment.