bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative Analysis of Topic Modeling Algorithms for Short Texts in Persian Tweets
Authors: Karimi Amir Hossein , Akbari Masoud , Akbari Mohammad 
Published: July 2023

Abstract
Topic modeling is a popular natural language processing technique to uncover hidden patterns and topics in extensive text collections. However, there is a lack of comprehensive studies that focus specifically on applying topic modeling algorithms to short texts, particularly from social media platforms. Even fewer studies have explored comparing different topic modeling algorithms for low-resource languages such as Persian. Our study aims to address this gap by thoroughly investigating topic modeling algorithms and metrics tailored for short texts, particularly Persian tweets. We collected and preprocessed a substantial dataset of Persian tweets. We also developed a dedicated tool that enables reproducibility and facilitates the evaluation of various topic modeling algorithms using the provided dataset. Our comparative analysis included Latent Dirichlet Allocation (LDA), Non-negative Matrix Factorization (NMF), Latent Semantic Indexing (LSI), Gibbs Sampling Dirichlet Mixture Model (GSDMM), and Correlated Topic Model (CTM). To measure their performance, we employed well-established metrics, namely Purity, Normalized Mutual Information (NMI), and Coherence. Our experimental results indicate that GSDMM and CTM+BERT exhibit superior performance compared to other algorithms in terms of purity and NMI on the Persian short-text topic modeling dataset. Additionally, CTM+BERT demonstrates competitive coherence performance compared to GSDMM. Our study provides valuable insights into the effectiveness of different topic modeling approaches for short texts and can help researchers select the most appropriate algorithm for their specific use case.
Demographic and Clinical Parameters Along with Hormonal Levels in Pediatric Patients with Chronic Kidney Disease: A Study of Pubertal Development Impacts
Authors: Önal Hülya Gözde , Önal Mesut , NALÇACIOĞLU Hülya , KARALI Demet Tekcan KARALI TEKCAN 
Published: July 2023

Abstract
Objective: Chronic kidney disease (CKD) is associated with growth retardation and delayed pubertal development in the pediatric population. This study aimed to investigate the impact of CKD on growth and pubertal development in children and adolescents by considering factors such as dialysis and transplantation.
Methods:A cross-sectional retrospective study was conducted in a cohort of 52 pediatric patients aged 0-18 diagnosed with stages 2-5 CKD, undergoing dialysis treatment or kidney transplantation. Demographic information, clinical characteristics, pubertal development, and treatment methods were also collected. The relationships between these factors and pubertal development were also analyzed.
Results:This study revealed significant delays in growth and pubertal development in children and adolescents with CKD. The mean age at menarche was 12.79, and 32.8% of the patients had primary amenorrhea. Patients on dialysis and those who underwent transplantation displayed further growth and pubertal outcomes. Factors such as the CKD stage (r = 0.35, p = 0.02) and age at diagnosis (r = -0.28, p = 0.01) significantly influenced the relationship between CKD and pubertal development. Results were associated with delayed pubertal growth in this population.
Conclusion:Our findings underscore the significant impact of CKD on the growth and pubertal development of children and adolescents. Early detection, intervention, and comprehensive management of CKD and its complications could aid in improving growth and pubertal outcomes in this vulnerable population.
Selective Blood Cell Hitchhiking in Whole Blood with Ionic Liquid-Coated PLGA Nanoparticles to Redirect Biodistribution After Intravenous Injection
Authors: Hamadani Christine M. , Dasanayake Gaya S. , Chism Claylee M. , Gorniak Meghan E. , Monroe Wake G. , Merrell Anya , Pride Mercedes C. , Heintz Rebekah , Wong Karen , Hossain Mehjabeen , Taylor George , Edgecomb Sara X. , Jones Deauntaye , Dhar Joy , Banka Alison , Singh Gagandeep , Vashisth Priyavrat , Randall Joh'nis , Darlington Donovan S. , Everett Jaylon , Jarrett Ethan , Werfel Thomas A. , Eniola-Adefeso Omolola , Tanner Eden E. L. 
Published: July 2023

Abstract
Less than 5% of intravenously-injected nanoparticles (NPs) reach destined sites in the body due to opsonization and immune-based clearance in vascular circulation. By hitchhiking in situ onto specific blood components post-injection, NPs can selectively target tissue sites for unprecedentedly high drug delivery rates. Choline carboxylate ionic liquids (ILs) are biocompatible liquid salts <100℃ composed of bulky asymmetric cations and anions. This class of ILs has been previously shown to significantly extend circulation time and redirect biodistribution in BALB/c mice post-IV injection via hitchhiking on red blood cell (RBC) membranes. Herein, we synthesized & screened 60 choline carboxylic acid-based ILs to coat PLGA NPs and present the impact of structurally engineering the coordinated anion identity to selectively interface and hitchhike lymphocytes, monocytes, granulocytes, platelets, and RBCs in whole mouse blood for in situ targeted drug delivery. Furthermore, we find this nanoparticle platform to be biocompatible (non-cytotoxic), translate to human whole blood by resisting serum uptake and maintaining modest hitchhiking, and also significantly extend circulation retention over 24 hours in BALB/c healthy adult mice after IV injection. Because of their altered circulation profiles, we additionally observe dramatically different organ accumulation profiles compared to bare PLGA NPs. This study establishes an initial breakthrough platform for a modular and transformative targeting technology to hitchhike onto blood components with high efficacy and safety in the bloodstream post-IV administration.
Epidemiology of Autism Spectrum Disorder in Buenos Aires, Argentina: Insights from Unique Disability ID Issuance Trends
Authors:   Agustina Aragón-Daud1, Vetere Giselle , Argañaraz Marina , Musich Francisco 
Published: July 2023

Abstract

Purpose: Autism Spectrum Disorder (ASD) prevalence rates vary greatly across regions and studies. Some countries, such as Argentina, have unknown rates. Due to this high heterogeneity in ASD prevalence worldwide, it is important to study its prevalence and characteristics in such countries to develop effective policies.
Methods: we analyzed official data from the Unique Disability IDs (UDIDs) issued for individuals with ASD in the Autonomous City of Buenos Aires from 2016 to 2021, examining age, gender, and diagnosis.
Results: most UDIDs were issued for males, for Pervasive Developmental Disorders, and almost half to individuals over 8 years old, with these trends remaining stable over these years. However, UDID issuance abruptly dropped in 2020.
Conclusions: our findings highlight epidemiological aspects of the autism population in Argentina, including challenges such as delayed diagnosis and high prevalence of broad diagnosis categories. Addressing these challenges requires further research and intervention to improve the quality of life of individuals with ASD.
Solutions to weighted complex m-Hessian equations on domains in Cn
Authors: Phu Nguyen Van , Dieu Nguyen Quang 
Published: July 2023

Abstract
In this paper, we first study the comparison principle for the operator Hχ,m. This result is used to solve certain weighted complex m- Hessian equations.
2010 Mathematics Subject Classification: 32U05, 32W20.
Circulation of Chikungunya virus in Rio Grande do Norte from 2019 to 2020: epidemiological and molecular aspects
Authors: Dias Jonai Pachêco , Pereira Raíssa Liane do Nascimento , Dantas Maria Eduarda Pessoa Lopes , Monteiro Joelma Dantas , Pereira Hannaly Wana Bezerra , de Oliveira Derley Galvão , de Souza Themis Rocha , de Araújo Josélio Maria Galvão 
Published: July 2023

Abstract

Background:
Once considered a third-world disease, Chikungunya Fever is currently one of the main emerging arboviruses globally. Shortly after having been established as an autochthonous disease in Brazil, Chikungunya virus (CHIKV) spread in the State of Rio Grande do Norte, where it has caused recurrent outbreaks. This study aims to describe epidemiological aspects of Chikungunya in the State of Rio Grande do Norte during 2019 and 2021.
Methods:
Samples of suspected cases of chikungunya from different municipalities in Rio Grande do Norte were analyzed. A total of 540 samples were tested using the qRT-PCR.
Results:
134 were chikungunya positive in 2019 (n = 82) and 2020 (n = 52), representing a total of 25% for both years. Most of those affected were female (60%) in the age group between 20 and 39 years old. The most frequent health issues associated with infection were fever (65%), headache (48%) and arthralgia (47%). We identified two (2/134) probable cases of congenital infection and two asymptomatic cases (1.5%). The highest mean viral load peak was found on the first day of symptom onset. The highest proportion of cases reported in 2019 was observed in Natal, in the Tirol neighbourhood (57%); and in 2020, in the municipality of Guamaré (33%).
Conclusions:
This study contributes to the Chikungunya population-based surveillance in urban centres of the state of Rio Grande do Norte, outlining higher incidence areas, which will serve as a basis for disease epidemiological control.
Environmental, social, and WASH factors affecting the recurrence of cholera outbreaks in displacement camps in Northeast Nigeria: a rapid appraisal
Authors: Jaber Tarek , Fame Thiaba , Agho Osas Aizeyosabor , Van de Walle Bartel , Bartram Jamie , Boelee Eline 
Published: July 2023

Abstract
In 2021, Nigeria witnessed a severe cholera outbreak that affected Borno state, in which more than 1,600,000 internally displaced persons (IDPs) resided at the time. This rapid appraisal explored factors that facilitate the recurrence of cholera outbreaks in sites hosting IDPs in Northeast Nigeria. Semi-structured interviews were conducted with water, sanitation, and hygiene (WASH), management, and healthcare personnel working in ten displacement camps in Borno state. The interviews were complemented by transect walks and field observations, measurements of free residual chlorine levels, and publicly available data published by the International Organization for Migration Displacement Tracking Matrix. The recurrence of cholera outbreaks appears to be facilitated by substantial interactions between IDPs and host communities, and suboptimal WASH services in camps. Of particular concern, IDP camps are exposed to extreme weather-related events that damage facilities and subsequently affect WASH practices. WASH services in camps may likewise be severely hindered by an influx of new arrivals. In conclusion, we emphasize the importance of expanding WASH activities to host communities and developing site-specific WASH interventions and chlorination targets. Practical recommendations are needed for the prevention and control of outbreaks following extreme weather-related events and population influxes.
Efficient adsorption of tartrazine from an aqueous solution using a low-cost orange peel powder
Authors: Honorine Amana Tokodne , Daouda Abia , T. Domga , Richard Domga , Guy Bertrand Noumi 
Published: July 2023

Abstract

Orange peel powder was activated using different methods and was used to remove tartrazine (E102) from an aqueous solution. The following three adsorbents were synthethized: orange peel powder activated thermally (POAT), orange peel powder activated with sulfuric acid (POAA), orange peel powder activated with soda (POAS). These adsorbents were then characterized by Fourier Transform Infra-Red Spectrometry (FTIR), Raman spectroscopy, powder X-Ray Diffraction (XRD), and point-of-zero charge. The experimental parameters such as contact time, dose of adsorbent, initial concentration of tartrazine, pH, and temperature were studied. The adsorption capacities of tartrazine for the optimal POAT, POAA, and POAS were found to be 121.74, 122.25, and 116.35 mg/g, respectively. The experimental data were analyzed by Freundlich and Temkin isotherm models, as well as the pseudo-second-order kinetic model.
Improved RUSLE model to simulate the effect of slope forest area on soil and water conservation
Authors: Wang Hui , Bai Yu , Man Xiaojun , Tang Zhiping , Zhang Shaoping 
Published: July 2023

Abstract

The problem of soil and water loss on slope land has always been one of the key issues that people pay attention to. How to reasonably arrange tree species and planting methods can effectively improve the current situation of water loss and soil erosion. The Revised Universal Soil Loss Equation (RUSLE) model is a widely used soil erosion prediction model, but it does not consider the impact of tree height and crown size on soil erosion. In this paper, six experimental plots of soil and water conservation were carried out on the forest slope land in southern China. Six experimental plots were planted with different trees, and all kinds of data were collected for 3 years. On the basis of data analysis and machine learning methods, it is found that tree height and crown have a significant impact on soil erosion, but have no significant impact on runoff formation. With the growth of trees, the amount of soil loss in each plot gradually decreases. At the same time, an improved RUSLE model related to tree height and crown has been established, which has a high simulation effect (R2 of testing reaches 0.6775, R2 of all data reaches 0.5452).
Therapeutic Potential and Molecular Mechanisms of the Multitargeted Flavonoid Fisetin
Authors: Rauf Abdur , Abu-Izneid Tareq , Imran Muhammad , Hemeg Hassan A. , Bashir Kashif , Aljohani Abdullah S.M. , Aljohani Mona S.M. , Alhumaydhi Fahad A. , Khan Ishaq N. , Bin Emran Talha , Gondal Tanweer Aslam , Nath Nikhil , Ahmad Ishtiaque , Thiruvengadam Muthu 
Published: July 2023

Abstract:Flavonoids effectively treat cancer, inflammatory disorders (cardiovascular and nervous systems), and oxidative stress. Fisetin, derived from fruits and vegetables, suppresses cancer growth by altering cell cycle parameters that lead to cell death and angiogenesis without affecting healthy cells. Clinical trials are needed in humans to prove the effectiveness of this treatment for a wide range of cancers. According to the results of this study, fisetin can be used to prevent and treat a variety of cancers. Despite early detection and treatment advances, cancer is the leading cause of death worldwide. We must take proactive steps to reduce the risk of cancer. The natural flavonoid fisetin has pharmacological properties that suppress cancer growth. This review focuses on the potential drug use of fisetin, which has been extensively explored for its cancer-fighting ability and other pharmacological activities such as diabetes, COVID-19, obesity, allergy, neurological, and bone disorders. Researchers have focused on the molecular function of fisetin. In this review, we have highlighted the biological activities against chronic disorders, including cancer, metabolic illnesses, and degenerative illnesses, of the dietary components of fisetin.
The Gulf Achievement of Cholesterol Targets in Out-Patients Study
(GULF ACTION): Design, Rationale, and Preliminary Results
Authors: Albackr Hanan B , Al Waili Khalid , Almahmeed Wael , Jarallah Mohammad Al , Amin Mohammad I , Alrasadi Khalid , Batais Mohammed A. , Almigbal Turky H. , Youssef Ali , Alghamdi Mohammad , Al Shehri Mohammad , Ahmad Islam , ElToukhy Riham A. , Kholaif Naji , Kinsara Abdulhalim J. , Al-Kindi Manal , Barzargani Nooshin , Hassan Magdy , Suwaidi Shamsa Al , Rajan Rajesh , Altaradi Hani , Alhabib Khalid F 
Published: July 2023

Aim:
To assess the current dyslipidemia management in the Arabian Gulf region by describing
the demographics, study design, and preliminary results of out-patients who achieved low-density
lipoprotein cholesterol (LDL-C) goals at the time of the survey.

Background:
The Arabian Gulf population is at high risk for atherosclerotic cardiovascular disease at
younger ages. There is no up-to-date study regarding dyslipidemia management in this region, especially
given the recent guideline-recommended LDL-C targets.

Objective:
Up-to-date comprehensive assessment of the current dyslipidemia management in the Arabian
Gulf region, particularly in view of the recent evidence of the additive beneficial effects of ezetimibe
and proprotein convertase subtilisin/kexin-9 (PCSK-9) inhibitors on LDL-C levels and cardiovascular
outcomes.

Methods:
The Gulf Achievement of Cholesterol Targets in Out-Patients (GULF ACTION) is an ongoing
national observational longitudinal registry of 3000 patients. In this study, adults ≥18 years on lipidlowering
drugs for over three months from out-patients of five Gulf countries were enrolled between
January 2020 and May 2022 with planned six-month and one-year follow-ups.

Results:
Of the 1015 patients enrolled, 71% were male, aged 57.9±12 years. In addition, 68% had atherosclerotic
cardiovascular disease (ASCVD), 25% of these patients achieved the LDL-C target, and
26% of the cohort were treated using combined lipid-lowering drugs, including statins.

Conclusion:
The preliminary results of this cohort revealed that only one-fourth of ASCVD patients
achieved LDL-C targets. Therefore, GULF ACTION shall improve our understanding of current
dyslipidemia management and “guideline gaps” in the Arabian Gulf region.
In Silico Study of the Structural Disruption of 14α-demethylase Induced
by the Binding of Terminalia chebula Constituents
Authors: Rani Nidhi , Singh Randhir , Kumar Praveen , Verma Nitin 
Published: July 2023

Background:
Since ancient times, medicinal plants have been in use in medicine and dai-ly life.

Objective:
To develop new antifungal compounds with low toxicity and high efficacy followed by high bioavailability, the constituents of Terminalia chebula were studied.

Methods:
The chemical constituents of the plant were evaluated for antifungal potential via Moler-go Virtual Docker against the enzyme 14α-demethylase.

Results:
The study depicted that tannins exhibited very good potential against the enzyme and could be used further for lead development.

Conclusion:
The study revealed that the plant possessed various constituents with potential antifun-gal properties and low toxicity.
Review on Hydrogel Based Systems and their use in Drug Delivery for
Wound Healing & Wound Management
Authors: Jayswal Meet A. , Ahlawat Priyanka , Patel Ashaben 
Published: July 2023

Abstract:
The largest organ of the human body, the skin, shields the body from the outside environment.
Despite having a great capacity for regeneration, major skin abnormalities cannot heal
on their own and must be covered with artificial skin. In recent years, significant advancements
have been achieved in the area of skin tissue engineering to create novel skin replacements. Because
of their porous as well as moisturized polymeric structural composition, hydrogels are one
of the choices with the greatest ability to imitate the natural skin microenvironment. Naturally
derived polymers, synthesized polymers, polymerizable synthetic monomolecules, as well as
mixtures of natural and synthesized polymers, can all be used to create hydrogels. They can be
used to assist in the regeneration as well as repair of the wounded dermis, epidermis or else both
by dressing various wounds permanently or temporarily. Hydrogels possess distinct properties
like lightweight, stretchable, biocompatible, and biodegradable; they have the potential to be incorporated
as flexible solutions for the care of chronic wounds. Additionally, these characteristics
make hydrogels appropriate for use in the pharmaceutical and medical industries. Physical,
chemical, and hybrid bonding are all involved in the creation of hydrogels. Several processes, including
solution casting, solution mixing, bulk crosslinking polymerization, the free radical
mechanism, radiation therapy, and the development of interpenetrating networks, are used to create
the bonding. This review primarily focuses on the type of wounds with phases in wound healing
and the many kinds of hydrogels based on cross-linking, ionic charge, physical properties,
source etc., and it also describes potential fabrication techniques for hydrogel design in biomedical
applications, drug delivery as well as wound management hydrogel systems. Hydrogel-based
systems for wound recovery and management are described, as well as current research & future
prospective of hydrogel-based drug delivery systems in wound healing for topical applications.
Effect of microwave and ultrasonic irradiation on the enzymatic hydrolysis of water hyacinth biomass in the presence of surfactants
Authors: Rokhati Nur , Ratnawati  , Prasetyaningrum Aji , Anggraini Widyah , Nugroho Akbar , Novita Nasyriyatul Hana , Andarani Pertiwi , Riyanto Teguh 
Published: July 2023

This paper presents the effect of microwave and ultrasound irradiation on the enzymatic hydrolysis of water hyacinth biomass in the presence of surfactants. Prior to hydrolyzing, the water hyacinth was treated utilizing alkali with and without microwave assistance. It was revealed that the microwave improved the removal of lignin and hemicellulose. The treated water hyacinth biomass was also characterized using Scanning Electron Microscope (SEM), X-ray Diffraction (XRD), and Fourier-Transform Infrared (FT-IR) Spectroscopy. The effect of surfactant and the assistance of microwave and ultrasound were comprehensively studied. Some parameters varied, including stirring speed, surfactant type, concentration, and reaction time. The results indicated that microwave and ultrasound could enhance the reaction rate. Tween 80 here could improve conventional, microwave-assisted, and ultrasound-assisted hydrolysis of water hyacinth biomass. It was found that the ultrasound-assisted hydrolysis was better than that of others. The results of this research can be used as the groundwork for further developing the lignocellulosic biomass hydrolysis process, especially in an advanced enzymatic hydrolysis process.
Pengaruh Teman Sebaya, Pendidikan Karakter, Keterampilan Belajar, Pemberian Reward Dan Interaksi Sosial Keluarga Terhadap Prestasi Belajar Siswa Kelas VIII Di MTsN 06 Padang
Authors: Mutiara Ica - , Stevani Stevani , Dahen Lovelly Dwinda 
Published: July 2023

This study aims to analyze the sampling technique was Proportional Random Sampling with a total sample of 113 students. The results showed that: 1), peers have a significant effect on learning achievement. Where indicated by the coefficient value of 0.336. This coefficient value is significant because the t-count is 3,477 > t-table is 1,65909. 2), character education has a significant effect on learning achievement. Where indicated by the coefficient value of 0.326. This coefficient value is significant because the value of t-count is 3.153 > t-table of 1.65909. 3), learning skills have a significant effect on learning achievement. Where indicated by the coefficient value of 0.180. This coefficient valueis significant because the value of t-count is 2.246 > t-table of 1.65909. 4), giving rewards have a significant effect on learning achievement. Where indicated by the coefficient value of 0.206. This coefficient value is significant because the value of t-count is 2,929 > t-table of 1,65909. 5), social family interactions have a significant effect on learning achievement. Where indicated by the coefficient value of 0.640. This coefficient value is significant because the value of t-count is 5,002 > t-table of 1,65909. 6), character education, learning skills, giving rewards, and social family interaction together have a significant effect on the learning achievement. Where obtained by the value of F-count 142.226 > F-table 2.30 with a significant level of 0.000 <= 0.05. This means that Ha is accepted and H0 is rejectedKeywords: Peers,Character Education, Learning Skills, Giving Rewards, And Social Family Interaction On Student Achievement.