bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Sticky Situation: Glue Migration during Hepatic Vein Embolization
Authors: Pal Koustav , Kuban Joshua D. , Murthy Ravi , Odisio Bruno C. , Metwalli Zeyad A. 
Published: July 2023

AbstractThe addition of hepatic venous embolization to portal venous embolization to achieve ipsilateral liver venous deprivation before major hepatectomy has been suggested to increase the extent of hypertrophy of the future liver remnant. The presented case discusses a hepatic vein embolization procedure complicated by the unintended migration of a glue cast used to achieve hepatic venous occlusion and subsequent management with endovascular retrieval of the glue cast from the inferior vena cava. The emerging role of hepatic venous embolization and associated complications are also discussed.
Partial Parasagittal Patellectomy in Dogs: A Retrospective Case Series of 19 Dogs
Authors: Dumitru Emilian Adrian , Garland Ben William , Allen Matthew J. 
Published: July 2023

AbstractObjective The aim of this study was to describe partial parasagittal patellectomy for the surgical management of patellar luxation, including surgical technique, proposed indications, complications, and outcomes in a cohort of dogs.Study Design This is a single-center retrospective clinical case series.Methods Medical records (2019–2020) of dogs presenting for patellar luxation were reviewed. Clinical signs, luxation direction and grade, preoperative imaging and intraoperative findings, and complications were retrospectively retrieved. Owners were contacted via questionnaire for medium- and long-term follow-up.Results A total of 24 stifles in 19 dogs met the inclusion criteria. Intraoperative minor complications occurred in four stifles. A single minor complication occurred postoperatively with no major complications. Increased thickness and radiographic attenuation of the patellar ligament were noted in 14 stifles at radiographic reassessment. Re-luxation was not encountered, with long-term owner-assessed outcome as good to excellent in all cases.Conclusion Partial parasagittal patellectomy, used in conjunction with block recession trochleoplasty and tibial tuberosity transposition, provided reliable resolution of patellar luxation in canine stifles with grade 2 or 3 luxation where width mismatch between the patella and the trochlea was noted intraoperatively. Long-term outcome appears to be good to excellent with a low rate of complication.
Electronic health record “gag clauses” and the prevalence of screenshots in peer-reviewed literature
Authors: Bapna Monika , Miller Kristen , Ratwani Raj M 
Published: July 2023

Abstract

Objective
To determine whether the Office of the National Coordinator’s policy change restricting the use of “gag clauses” in contracts between electronic health record (EHR) vendors and healthcare facilities increased the prevalence of screenshots in peer-reviewed literature.

Materials and Methods
We reviewed EHR usability and safety-related peer-reviewed journal articles from 2015 to 2023 and quantified the number of articles containing screenshots. For those that did not contain screenshots, we identified whether they would have benefited from screenshots.

Results
When gag clauses were permitted 6 of 79 (7.6%) of articles contained screenshots and 8 (10.1%) would have benefited from screenshots. When gag clauses were restricted 3 of 40 (7.5%) contained screenshots and 8 (20%) would have benefited from screenshots.

Discussion
The policy change does not appear to have an impact on the prevalence of screenshots in peer-reviewed literature.

Conclusions
Additional steps are necessary to promote the use of screenshots in peer-reviewed literature.
Eastern Nature
Authors: Ragan Mark A. 
Published: July 2023

Abstract
There is only fleeting evidence that early cultural, philosophical, or religious traditions in the Indian subcontinent, China, or Japan held plants and animals to be comprehensive, mutually exclusive groupings in the natural world. This chapter explores high-level concepts of natural beings in the Vedic, Buddhist, Confucian, Taoist, Mohist, and syncretic Shintō traditions. It is unlikely that the later Hellenic, Mediterranean, or European philosophical traditions drew significantly on Eastern sources for a high-level distinction between plants and animals.
Nature’s mystic book
Authors: Ragan Mark A. 
Published: July 2023

Abstract
This chapter explores plants, animals, and intermediate organisms as they appear in occult writings and practise including the Hermetic tradition, Gnostic texts, alchemy, mystery-books, and magic. Plants and animals were only loosely demarcated in Hermetic and Gnostic texts. Building on Neoplatonic cosmology, Hermetic texts described a web of occult sympathies and antipathies that link macrocosm (the cosmos) and microcosm (man), and might be exploited for good (e.g. healing) or evil. On the eve of the Italian Renaissance, an extensive occult literature acknowledged only animals, vegetables, and minerals. Pico della Mirandola, Gianfrancesco Pico, and Agrippa considered zoophytes to have a distinct nature. Paracelsus ignored zoophytes, but many later alchemists followed Agrippa. Minerals, vegetables, and animals were first called Kingdoms in Novum lumen chymicum (1614) and Tractatvs de svlphvre (1616). Bruno but not Fludd held zoophytes to be intermediate beings. Francis Bacon abandoned macrocosm-microcosm theory in 1605.
From histoire naturelle to anatomie and morphologie
Authors: Ragan Mark A. 
Published: July 2023

Abstract
This chapter examines the development of high-level biological classification in France from the mid-Eighteenth to the mid-Nineteenth centuries. The period 1750–1800 brought revolution to natural history in France, as Buffon and the Encyclopédie gave way to the Muséum d’histoire naturelle. Lamarck reordered the animaux sans vertèbres, proposing not only his well-known trees of animal relations (1809, 1815) but also, just before his death, a major variant. Cuvier’s four embranchemens dismembered the animal series; Geoffroy Saint-Hilaire tried to restore a unity of plan. Diverse arrangements at the plant-animal boundary, including an important (albeit problematic) new “third kingdom”, are seen in works of seven other naturalists who wrote in French between 1786 and 1856.
Pedaling towards sustainability: a mixed-method study of the drivers and barriers to bike-sharing adoption
Authors: Sajid Muhammed , Midhun V. , Zakkariya K.A. , Surira Mukul Dev , Vishnu K.P. 
Published: July 2023

PurposeThe purpose of this study is to investigate the motivations and barriers behind the adoption of bike-sharing services, explore the influence of individual values and environmental knowledge on bike-sharing adoption and analyze the relationship between reasons, attitude and intention to utilize bike-sharing.Design/methodology/approachThe study initially conducted a semi-structured interview with 19 bike-sharing users and performed a thematic analysis to identify the context-specific motivators and barriers. The identified factors were then incorporated into the behavioral reasoning theory (BRT) framework and quantitatively examined using the data gathered from 412 Indian bike-sharing users.FindingsThe findings outlined the complex reasoning process underlying bike-sharing adoption and how environmental value and attitude are related to the reasons. Further, the study examined the moderating impact of environmental knowledge, which was overlooked in previous studies.Practical implicationsThe study provides valuable suggestions to bike-sharing businesses, which helps them to induce facilitators and remove barriers.Originality/valueBehavioral research in bike-sharing is in its embryonic stage. This is one of the initial attempts to address this knowledge deficit by comprehensively examining the factors affecting bike-sharing intention through the theoretical lens of BRT.
Data usefulness in determining cause of stillbirth in South Asia
Authors: Goldenberg Robert L. , Hwang Kay , Saleem Sarah , Tikmani Shiyam Sunder , Yogeshkumar S. , Kulkani Vardendra , Ghanchi Najia , Harakuni Sheetal , Ahmed Imran , Uddin Zeeshan , Goudar Shivaprasad S. , Guruprasad Gowder , Dhaded Sangappa , Goco Norman , Silver Robert M. , McClure Elizabeth M. 
Published: July 2023

AbstractObjectiveTo evaluate the usefulness of data to determine cause of stillbirth in India and Pakistan.DesignProspective, observational study.SettingsStudy hospitals in India and Pakistan.Population200 fetal deaths with placental evaluation and minimally invasive tissue sampling (MITS) of internal organs and polymerase chain reaction (PCR) test for 75 pathogens.Main outcome measuresData defined as useful to determine stillbirth causes.ResultsPlacental pathology was the most useful to determine cause of stillbirth. Comparing placental and fetal weight with standard weights was useful in 44.5% and 48.5%, respectively. Lung histology was useful in 42.5%. Most of the other findings of internal organ histology were only occasionally useful. Signs of abruption, by maternal history or placental evaluation, were always deemed useful. Placenta, brain and cord blood PCR were also useful, but less often than histology.ConclusionBased on this analysis, maternal clinical history, placental histology and fetal examination were most informative. Comparing the placental and fetal weights with recognised standards was useful in nearly half the cases. Fetal tissue histology and PCR were also informative. Of all the potential tests of MITS‐obtained specimens, we would first recommend histological evaluation of the lungs, and using a multiplex PCR platform would determine pathogens in blood and brain/CSF. We recognise that this approach will not identify some causes, including some genetic and internal organ anomalies, but will confirm most common causes of stillbirth and most of the preventable causes of stillbirth in low‐ and middle‐income countries.
Diuretics or ultrafiltration in the treatment of acute decompensated heart failure: An updated systematic review and meta‐analysis
Authors: Terpos Vasileios , Roumeliotis Stefanos , Georgianos Panagiotis I. , Papa Eleni , Tsalikakis Dimitrios G. , Papachristou Evangelos , Liakopoulos Vassilios 
Published: July 2023

AbstractIntroductionHospitalization for decompensated heart failure is a major public health issue.MethodsWe performed a meta‐analysis to summarize and analyze if there is a benefit in using ultrafiltration over diuretics in terms of reducing mortality or hospital readmissions, primarily and identified 10 randomized controlled trials (RCTs) including 941 patients.ResultsCompared to diuretics, treatment with ultrafiltration was associated with a significant reduction in heart failure hospitalizations (risk ratio [RR]: 0.72; 95% confidence interval [CI]: 0.55–0.96, p = 0.02) and significant increase in weight and net fluid loss (mean difference [MD]: −1.55, CI: −2.36 to −0.74, p = 0.0002) and (MD: −2.10, CI: −3.32 to −0.89, p = 0.0007), respectively. There was no significant difference among treatments regarding the duration of hospitalization, the increase in serum creatinine levels, and mortality.ConclusionAmong patients with decompensated heart failure, compared to diuretics, ultrafiltration is associated with reduced rehospitalizations and increased weight/net fluid loss.
Experimental nest cooling reveals dramatic effects of heatwaves on reproduction in a Mediterranean bird of prey
Authors: Corregidor‐Castro Alejandro , Morinay Jennifer , McKinlay Susan E. , Ramellini Samuele , Assandri Giacomo , Bazzi Gaia , Glavaschi Alexandra , De Capua Enrico L. , Grapputo Alessandro , Romano Andrea , Morganti Michelangelo , Cecere Jacopo G. , Pilastro Andrea , Rubolini Diego 
Published: July 2023

AbstractFuture climatic scenarios forecast increases in average temperatures as well as in the frequency, duration, and intensity of extreme events, such as heatwaves. Whereas behavioral adjustments can buffer direct physiological and fitness costs of exposure to excessive temperature in wild animals, these may prove more difficult during specific life stages when vagility is reduced (e.g., early developmental stages). By means of a nest cooling experiment, we tested the effects of extreme temperatures on different stages of reproduction in a cavity‐nesting Mediterranean bird of prey, the lesser kestrel (Falco naumanni), facing a recent increase in the frequency of heatwaves during its breeding season. Nest temperature in a group of nest boxes placed on roof terraces was reduced by shading them from direct sunlight in 2 consecutive years (2021 and 2022). We then compared hatching failure, mortality, and nestling morphology between shaded and non‐shaded (control) nest boxes. Nest temperature in control nest boxes was on average 3.9°C higher than in shaded ones during heatwaves, that is, spells of extreme air temperature (>37°C for ≥2 consecutive days) which hit the study area during the nestling‐rearing phase in both years. Hatching failure markedly increased with increasing nest temperature, rising above 50% when maximum nest temperatures exceeded 44°C. Nestlings from control nest boxes showed higher mortality during heatwaves (55% vs. 10% in shaded nest boxes) and those that survived further showed impaired morphological growth (body mass and skeletal size). Hence, heatwaves occurring during the breeding period can have both strong lethal and sublethal impacts on different components of avian reproduction, from egg hatching to nestling growth. More broadly, these findings suggest that the projected future increases of summer temperatures and heatwave frequency in the Mediterranean basin and elsewhere in temperate areas may threaten the local persistence of even relatively warm‐adapted species.
Influence of the orthodontic bonding procedure on biofilm formation
Authors: Blochberger Bijan Levent , Symmank Judit , Nitzsche Ánn , Nietzsche Sandor , Steiniger Frank , Guellmar André , Reise Markus , Sigusch Bernd , Jacobs Collin , Hennig Christoph‐Ludwig 
Published: July 2023

AbstractIntroductionIn orthodontics, white spot lesions are a persistent and widespread problem caused by the demineralization of buccal tooth surfaces around bonded brackets. The remaining adhesive around the brackets leads to surface roughness, which might contribute to demineralization. The present in vitro study aimed to compare a conventional and a modern adhesive system (APC Flash‐Free technology) for orthodontic brackets with regard to the adhesion of Streptococcus sobrinus, a leading caries pathogen.MethodsThis in vitro study included 20 premolar teeth and compared 10 APC Flash‐Free adhesive‐coated ceramic brackets (FF)with 10 conventionally bonded (CB) ceramic clarity brackets. Specimens were incubated in an S. sobrinus suspension for 3 h. To evaluate the bacterial formation, samples were analysed with a scanning electron microscope (SEM). Imaging software was used to quantify and statistically compare percentage values of colonization (PVC) in both groups' adhesion and transition areas.ResultsWe found a significant difference in biofilm formation between the groups for the adhesive and transition areas. PVC in the adhesive area was approximately 10.3‐fold greater for the CB group compared with the FF group (median: 3.2 vs 0.31; P < 0.0001). For the transition area, median PVC was approximately 2.4‐fold greater for the CB group compared with the FF group (median: 53.17 vs 22.11; P < 0.01).ConclusionsThere was a significantly lower level of S. sobrinus formation around the FF bracket system than there was surrounding the conventionally bonded group. This study suggests that the FF adhesive bracket system can help reduce the occurrence of bacterial growth around orthodontic brackets.
Grooving in the midcontinent: A tectonic origin for the mysterious striations of L’Anse Bay, Michigan, USA
Authors: Alemu Tadesse B. , Hodgin Eben B. , Swanson-Hysell Nicholas L. 
Published: July 2023

Abstract
A striated surface is present at an erosional unconformity between foliated Paleoproterozoic Michigamme Formation and fluvial conglomerate and sandstone of the Neoproterozoic Jacobsville Formation exposed at L’Anse Bay (Michigan, USA). These striations have been interpreted to be the result of ice flow in either the Proterozoic, the Pleistocene, or the modern. Recently, the glacial origin interpretation for this striated surface has been used to argue that it may be related to ca. 717–635 Ma Cryogenian snowball Earth glaciation. This interpretation would make the surface a rare example of a Neoproterozoic glacial pavement, with major chronostratigraphic implications that in turn impose constraints on the timing of intracratonic erosion related to the formation of the Great Unconformity. In this contribution, we present new observations showing that the surface is a tectonic slickenside caused by largely unconformity-parallel slip along the erosional unconformity. We document structural repetition of the Michigamme-Jacobsville contact with associated small-scale folding. The unconformity-parallel slip transitions into thrust faults that ramp up into the overlying Jacobsville Formation. We interpret that the surface records contractional deformation rather than ancient glaciation, recent ice movement, or recent mass wasting. The faulting likely occurred during the Rigolet phase of the Grenvillian orogeny, which also folded the Jacobsville Formation in the footwall of the Keweenaw fault.
Decoupled Oligocene mylonitic shearing and Miocene detachment faulting in the East Humboldt Range metamorphic core complex, northeast Nevada, USA
Authors: Zuza Andrew V. , Dee Seth 
Published: July 2023

AbstractThe relationships between brittle detachment faulting and ductile shear zones in metamorphic core complexes are often ambiguous. Although it is commonly assumed that these two structures are kinematically linked and genetically related, direct observations of this coupling are rare. Here, we conducted a detailed field investigation to probe the connection between a detachment fault and mylonitic shear zone in the Ruby Mountain–East Humboldt Range metamorphic core complex, northeast Nevada. Field observations, along with new and published geochronology, demonstrate that Oligocene top-to-the-west mylonitic shear zones are crosscut by ca. 17 Ma subvertical basalt dikes, and these dikes are in turn truncated by middle Miocene detachment faults. The detachment faults appear to focus in preexisting weak zones in shaley strata and Mesozoic thrust faults. We interpret that the Oligocene mylonitic shear zones were generated in response to domal upwelling during voluminous plutonism and partial melting, which significantly predated the middle Miocene onset of regional extension and detachment slip. Our model simplifies mechanical issues with low-angle detachment faulting because there was an initial dip to the weak zones exploited by the future detachment-fault zone. This mechanism may be important for many apparent low-angle normal faults in the eastern Great Basin. We suggest that the temporal decoupling of mylonitic shearing and detachment faulting may be significant and underappreciated for many of the metamorphic core complexes in the North American Cordillera. In this case, earlier Eocene–Oligocene buoyant doming may have preconditioned the crust to be reactivated by Miocene extension, thus explaining the spatial relationship between structures.
Coupling rare earth element analyses and high-resolution topography along fault scarps to investigate past earthquakes: A case study from the Southern Apennines (Italy)
Authors: Bello Simone , Perna Maria Grazia , Consalvo Ada , Brozzetti Francesco , Galli Paolo , Cirillo Daniele , Andrenacci Carlo , Tangari Anna Chiara , Carducci Andrea , Menichetti Marco , Lavecchia Giusy , Stoppa Francesco , Rosatelli Gianluigi 
Published: July 2023

AbstractThe systematic study of faults that have released strong earthquakes in the past is a challenge for seismic hazard assessment. In carbonate landscapes, the use of rare earth element (REE) concentrations on slickensides may aid the reconstruction of fault slip history. We applied this methodology to the Caggiano normal fault (Southern Apennines, Italy), cropping out southeast of the Irpinia 1980 CE earthquake fault (Mw 6.9), which was responsible for both the 1561 CE and partly the 1857 CE Basilicata earthquakes (Mw 6.7 and 7.1). We integrated the REE analysis approach with a high-resolution topographic analysis along 98 serial topographic profiles to measure vertical separations attributable to faulting since the Last Glacial Maximum (LGM). The asymmetric scarp height profiles suggest fault-lateral propagation and along-strike variations in the fault evolution. Our results indicate the occurrence of 7 to 11 earthquakes with variable slip between ~40 cm and ~70 cm within post-LGM times. We estimated the magnitudes of the respective earthquakes, between 5.5 and 7.0, and most commonly between 6.3 and 6.5. The results suggest a recurrence time between 1.6 k.y. and 2.3 k.y. and a slip rate ranging between 0.6 mm/yr and 0.9 mm/yr. This approach may be useful for application to carbonate fault planes in similar tectonic contexts worldwide.
Impact of the SARS-CoV-2 nucleocapsid 203K/204R mutations on the inflammatory immune response in COVID-19 severity
Authors: Shuaib Muhammad , Adroub Sabir , Mourier Tobias , Mfarrej Sara , Zhang Huoming , Esau Luke , Alsomali Afrah , Alofi Fadwa S , Ahmad Adeel Nazir , Shamsan Abbas , Khogeer Asim , Hashem Anwar M. , Almontashiri Naif A. M. , Hala Sharif , Pain Arnab 
Published: July 2023

Abstract
Background
The excessive inflammatory responses provoked by SARS-CoV-2 infection are critical factors affecting the severity and mortality of COVID-19. Previous work found that two adjacent co-occurring mutations R203K and G204R (KR) on the nucleocapsid (N) protein correlate with increased disease severity in COVID-19 patients. However, links with the host immune response remain unclear.

Methods
Here, we grouped nasopharyngeal swab samples of COVID-19 patients into two cohorts based on the presence and absence of SARS-CoV-2 nucleocapsid KR mutations. We performed nasopharyngeal transcriptome analysis of age, gender, and ethnicity-matched COVID-19 patients infected with either SARS-CoV-2 with KR mutations in the N protein (KR patients n = 39) or with the wild-type N protein (RG patients n = 39) and compared to healthy controls (n = 34). The impact of KR mutation on immune response was further characterized experimentally by transcriptomic and proteomic profiling of virus-like-particle (VLP) incubated cells.

Results
We observed markedly elevated expression of proinflammatory cytokines, chemokines, and interferon-stimulated (ISGs) genes in the KR patients compared to RG patients. Using nasopharyngeal transcriptome data, we found significantly higher levels of neutrophils and neutrophil-to-lymphocyte (NLR) ratio in KR patients than in the RG patients. Furthermore, transcriptomic and proteomic profiling of VLP incubated cells confirmed a similar hyper-inflammatory response mediated by the KR variant.

Conclusions
Our data demonstrate an unforeseen connection between nucleocapsid KR mutations and augmented inflammatory immune response in severe COVID-19 patients. These findings provide insights into how mutations in SARS-CoV-2 modulate host immune output and pathogenesis and may contribute to more efficient therapeutics and vaccine development.