bluuebunny/crossref_metadata_2025_split huggingface dataset:
Serum level of certain cytokines associated with psoriasis progression in Iraqi patients
Authors: Sami Mahdi Raffif , Ibrahim Salman Maryam , AlChalabi Rawaa 
Published: September 2023

Introduction and Aim: Psoriasis is a skin ailment that typically affects the scalp, lower back, knees, elbows, and results in flaky skin patches. The purpose of this study was to compare cytokines, leptin, and adiponectin levels, as well as several physiological characteristics, in psoriasis patients with and without treatment to levels in healthy people in Iraq.

Materials and Methods: The study included 310 subjects, males and females aged (25-65) years. The patients were attending a dermatology consultant at Al-Yarmouk Teaching Hospital in Baghdad. Blood samples were collected by venipuncture from all individuals. The Sandwich ELISA was used to estimate serum levels of IL-2, IL-8, IL-22, TNF-alpha, IFN-gamma, ADP and Leptin.

Results: Patients with psoriasis had considerably decreased lymphocyte and RBC counts while having significantly higher neutrophil, platelet, NLR, and PLR counts. WBC mean values in females and males among control groups were 7.16 ± 3.09x 103/µl and 8.6 ±3.62 x103/µl respectively. In psoriasis patients the WBC counts varied from 3.69 x103/µl to 12.8 x103/µl with a mean of 7.27 x 103/µl in female patients and from 6.47 x 103/µl to 13.62 x103/µl in males. Serum levels of cytokines, leptin and adiponectin were significantly higher in Group I patients, while in Group II it was almost like levels in the control group.

Conclusion: Smoking is a risk factor for psoriasis. Lymphocytes, erythrocytes, and hemoglobin levels are decreased in patients with psoriasis, while platelets and cytokines are elevated, signifying a relationship between these immunological parameters and development and severity of psoriasis disease.
Evaluation of in vitro antioxidant, anti-inflammatory and antibacterial activities of chloroform leaf extracts of Conocarpus lancifolius Engl
Authors: Parthiban Periyasamy , Saravanakumar Arthanari , Mohanraj Subramanian , Kavinkumar Chellamuthu , Sekar Abinayashree , Gowtham Arumugam , Sabari Somasundharam , Venkatachalam Nandhiya , Mutheeswaran Subramanian 
Published: September 2023

Introduction and Aim: Antibacterial substances are abundant in medicinal herbs, which are used in many extremely effective traditional medical therapies. Conocarpus lancifolius Engl. a plant species, has a wide range of therapeutic uses for the handling of haemophilia, inflammation, illness, eye ailments, fever, diabetes and headache. The study's goal was to assess the antibacterial efficacy, in vitro antioxidant, anti-inflammatory properties of the solvent-based extract of C. lancifolius leaf material.

Methodology: The investigation started in March 2023 and C. lancifolius leaves were collected in Tamil Nadu, India. To make the extracts, the maceration technique was employed. The phytochemical constitutions were identified by phytochemical test results. Using the agar diffusion method, the antibacterial capacity of C. lancifolius extracted from leaves was evaluated.

Results: At the concentration of 100 microgram/mL level of probability, Gram-positive bacteria including Staphylococcus aureus in addition to Bacillus cereus, respectively (18 and 21 mm) and Gram-negative microorganisms Escherichia coli combined with Klebsiella pneumoniae (23 and 20 mm) were considerably inhibited. Additionally, it has the strongest antifungal activity (20 mm) against Candida albicans. While the ethanol extract of the leaves significantly inhibited both Gram-negative bacteria like Escherichia coli as well as the pneumonia-causing bacteria Klebsiella pneumoniae (22 and 19 mm) and Gram-positive bacteria like Staphylococcus aureus and the yeast Bacillus cereus (18 and 20 mm).

Conclusion: When compared to normal ascorbic acid, which had an antioxidant activity of 87.96 percent, C. lncifolius extract with chloroform exhibited a substantial antioxidant activity of 62.96 percent inhibition. When compared to a larger dose of normal diclofenac (84.11 percent), the more potent quantity of C. lncifolius extract with chloroform significantly inhibited inflammation by 75.12 percent under similar circumstances. Because there are biologically active compounds in the herbal preparation, the current investigation found that C. lancifolius may be a good therapeutic candidate.
Diagnostic pitfalls in low grade appendiceal mucinous neoplasms
Authors: George Lovely , Reba Philipose Thoppil , K. Thushara , S. Rao Purnima 
Published: September 2023

Primary neoplasms of the appendix are present in less than 2% of appendicectomy specimens. Appendiceal mucinous neoplasm is a rare malignancy which is found in less than 0.3% of appendicectomy specimens and accounts for around 1% of gastrointestinal neoplasms. These have varying malignant potential and include a heterogeneous group of diseases. According to the WHO 5th edition (2019), the neoplastic spectrum of appendiceal mucinous neoplasms comprise of low-grade appendiceal mucinous neoplasms (LAMNs), high grade appendiceal mucinous neoplasms (HAMNs), and mucinous adenocarcinoma of the appendix. The patients with mucinous appendiceal lesions are frequently operated for symptoms resembling acute appendicitis as they lack specific clinical and imaging presentation. Categorisation of these neoplasms with attention to extent of mucin and neoplastic cells is crucial to stage the disease as well as to assess the risk of pseudomyxoma peritonei (PMP), a life threatening complication with poor prognosis. We present 8 LAMNs including a rare case of synchronous mucinous cystadenoma of ovary and LAMNs. We discuss the different clinical presentations and the challenges faced in diagnosis.
Galectin -3: an independent cardiac marker of left ventricular (LV) remodeling in chronic heart failure
Authors: Leesha Fernando Mario , Silambanan Santhi 
Published: September 2023

Introduction and Aim: Heart failure (HF) with increased morbidity and mortality is a critical condition where the cardiac pumping capacity fails to meet up with the body’s demand. Its development is silent due to slow, progressive remodeling presenting with symptoms later. Brain Natriuretic peptides (BNP) denotes ventricular loading status which do not reveal other mechanisms whereas a novel marker Galectin-3 (Gal-3) provides information about cardiac structural changes which includes inflammation, fibrosis, remodeling for guiding treatment. Research studies demonstrated that there is upregulation of Galectin- 3 in both acute and chronic heart failure (CHF) individuals. The objectives of our study were to compare Galectin- 3 levels in moderate and severe LVD CHF patients and determine whether serum Galectin -3 can be used as an independent cardiac marker of ventricular structural remodeling in such HF individuals.

Materials and Methods: 80 patients between 20 - 80 years diagnosed with CHF using Framingham criteria with ejection fraction (EF) of 45% and classified into two groups:(i) moderate LVD and (ii) severe LVD. Those with abnormal kidney functions were excluded. Comparison was done between serum Galectin - 3 and BNP; Gal- 3 was determined to be an independent marker of structural remodeling of LV between the two categories.

Results: Galectin-3 and BNP were significantly increased in HF with severe LVD than moderate LVD. Multivariate linear regression showed Galectin-3 as an independent predictor of LV remodeling with respect to changes in LV end- diastolic dimension with statistically significant p 0.001 whereas BNP did not show any such significance.

Conclusion: Galectin -3 and BNP levels were elevated in severe LV dysfunction than moderate LVD and concluded that Gal-3 is an independent cardiac biomarker of LV remodeling in Chronic heart failure.
Influence of fish on biochemical markers: A comparative study among male subjects of fish eaters and vegetarians
Authors: Prabhu Asha , H. P. Kedilaya , Shantaram Manjula 
Published: September 2023

Introduction and Aim: Cardiovascular diseases (CVD) are the major causes of morbidity and mortality in India. Intake of a high or moderate amount of fish has shown a decreased risk of CVD. This is due to the presence of long-chain n-3 polyunsaturated fatty acids (PUFA), such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in fish oils. According to past studies, regularly consuming these fatty acids lowers the risk of heart failure, myocardial infarction, endothelial dysfunction, inflammation, arrhythmias, and sudden death. The beneficial effects of a fish-rich diet appear to conflict with PUFA's susceptibility to oxidation. As a result, the study aimed to compare the lipid profile, cardiac markers, and lipid peroxidation status in male adults who consume moderate amounts of fish regularly.

Materials and Methods: Total cholesterol (T.C.), HDL-cholesterol (HDL-C), triglycerides (T.G.), high sensitive C-reactive protein (hs-CRP), Lipoprotein (a) [Lp(a)], Malondialdehyde (MDA) and antioxidant activity (AOA) were measured in healthy male individual of 85 fish eaters and 77 vegetarians in the age group of 25-40 years. The atherogenic indices TC/ HDL-C, LDL-C/HDL-C, a Student's 't' test, and non-HDL-C/ HDL-C were determined. The two groups' parameters were compared using the Student's t-test.

Results: In Fish eating male subjects, the lipid profile and cardiac markers were decreased except for HDL-C (which was increased). Fish eaters exhibited significant decreases in atherogenic indices, and significant variation was not observed in the oxidant status of the study groups (p>0.05).

Conclusion: According to the present study's findings, regular intake of moderate amounts of fish is linked to a decrease in lipid profiles and cardiac markers without affecting the individual's oxidation status.
TERRITÓRIOS CARIOCAS EM TEMPOS DE PANDEMIA:
Authors: Soares Joice De Souza , Assumpção Thais Lourenço 
Published: September 2023

A pandemia provocada pelo Novo Coronavírus (Sars-Cov-2) impôs uma série de transformações no que tange Ã s relações econômicas, políticas e sociais ao redor do globo. No Brasil, a partir de março de 2020, as orientações das diferentes esferas de governo, ainda que muitas vezes marcadas por certo descompasso, sinalizaram para medidas de distanciamento e/ou isolamento social. Especificamente no município do Rio de Janeiro, objeto de análise neste estudo, o cumprimento dessas diretrizes se dera de forma distinta nos territórios. Neste artigo, busca-se compreender em que medida as dinâmicas territoriais de contaminação e morte pela Covid-19 no município carioca auxiliam na compreensão de aspectos sociais de diferenciação e desigualdade na cidade.
Destruição econômica mútua assegurada: A escalada das tensões entre EUA e China
Authors: Botelho Maurilio Lima 
Published: September 2023

Resenha de: Allison, Graham. A caminho da Guerra: os Estados Unidos e a China conseguirão escapar da Armadilha de Tucídides? Rio de Janeiro: Intrínseca, 2020, 185 pp. Tradução de Cássio de Arantes Leite.
Análise da Cobertura de Hidrantes de Coluna no Município do Rio de Janeiro - Brasil
Authors: Da Silva Arthur Jorge de Veras , De Souza Marcelo Leite , Fidelis Jeferson Esteves , Da Cunha Mario Cesar Castro , De Veras Bruna Medeiros Gonçalves , Marino Tiago Badre , Xavier-da-Silva Jorge 
Published: September 2023

A cobertura da totalidade da área de uma localidade não depende somente de uma quantidade mínima de hidrantes, mas também é fundamental analisar a distribuição espacial destes recursos. Neste sentido, o presente estudo tem como objetivo analisar a cobertura dos hidrantes de coluna em todo o município do Rio de Janeiro, classificando os bairros conforme seu Índice de Cobertura de Hidrantes. Desse modo, foi desenvolvido o Índice de Cobertura de Hidrantes (ICH). O ICH foi calculado com a divisão da área total de cobertura dos hidrantes existentes pela da área urbana da localidade. A utilização do ICH visa medir a porcentagem de cobertura de cada bairro, possibilitando uma analise quantitativa e qualitativa do posicionamento dos hidrantes. Uma análise socioeconômica dos bairros com maior ICH evidencia uma maior cobertura em locais de alto poder aquisitivo e locais turísticos (Zona Sul).
Belzutifan (Welireg)
Authors: CADTH  
Published: September 2023

CADTH recommends that Welireg should be reimbursed by public drug plans for the treatment of adult patients with von Hippel-Lindau (VHL) disease who require therapy for associated nonmetastatic renal cell carcinoma (RCC), central nervous system (CNS) hemangioblastomas, or nonmetastatic pancreatic neuroendocrine tumours (pNET), not requiring immediate surgery if certain conditions are met.
Welireg should only be covered to treat adult patients with VHL disease who require therapy for associated nonmetastatic RCC, CNS hemangioblastomas, or nonmetastatic pNET, not requiring immediate surgery. Patients receiving Welireg should be in relatively good health.
Welireg should only be reimbursed if it is prescribed by specialists with expertise in VHL disease-associated tumours and if the cost of Welireg is reduced. Welireg should not be used in combination with other anti-tumour drugs.
ПРОБЛЕМЫ СОХРАНЕНИЯ ТРАДИЦИОННОЙ МУЗЫКИ КАЗАХСКОЙДИАСПОРОЙ ЗА РУБЕЖОМ
Authors: Абдурахманов Н.А. 
Published: September 2023

Мақалада алыс-жақын шет елдердегі қазақ диаспорасының дәстүрлі музыкасының, ұлттық өнерінің сақталу деңгейі, дамуы мен дағдарысқа түсуі, атажұрттан алыстағы қандастардың ұлттық рухын сақтау жолдары сараланып, дәстүрлі өнеріміздің келешегі мейлінше зерттеп-зерделеніледі. Шынтуайтында еліміз өзінің тәуелсіздігін нығайта түсумен қатар, алыс және жақын шетелдердегі қазақ диаспорасына ерекше көңіл бөле бастады. Кезінде қазақ жерінен әр түрлі себептермен басқа аумақтарға ауа көшкен қандастарымыздың тарихы қай-қайсысымызды да ойландырмай қоймайды. Өйткені, олар сол бөтен елде жүріп-ақ өзінің ұлттық болмысын, тарихи жадын, негізгі құндылықтарын, әсіресе ұлттық музыкасын сақтап қалуға күшін сарқа жұмсап келеді. Әсіресе авторлар көршілес Өзбекстан мен Қырғызстандағы, Түрікменстандағы отандастардың рухани әлеуетіне баса мән бере отырып, Қытай мен Моңғолия, Иран қазақтарының дәстүрлі музыкасын да назардан тыс қалдырмауға тырысады.
В статье рассматривается уровень сохранения, развития и кризисного состояния традиционной музыки, национального искусства казахской диаспоры в странах ближнего и дальнего зарубежья. Также будут проанализированы пути сохранения национального духа далеких от отчизны соотечественников и изучены перспективы казахского традиционного искусства за рубежом.Наряду с укреплением своей независимости наша страна стала уделять особое внимание казахской диаспоре в странах ближнего и дальнего зарубежья. История наших соотечественников, которые в свое время по разным причинам переехали с казахской земли на другие территории, не может не волновать ни одного из нас. Ведь они, находясь в этой чужой стране, прилагают все усилия, чтобы сохранить свою национальную идентичность, историческуюпамять, основные ценности, особенно национальную музыку.Особенно авторы стараются уделить особое внимание духовному потенциалу соотечественников в соседних Узбекистане, Кыргызстане, Туркменистане и не оставлять без внимания традиционную музыку казахов Китая, Монголии, Ирана.
The article examines the level of preservation, development and crisis state of traditional music, national art of the кazakh diaspora in the countries of the near and far abroad. The ways of preserving the national spirit of compatriots far from the motherland will also be analyzed and the prospects of кazakh traditional art abroad will be studied.Along with strengthening its independence, our country began to pay special attention to the Kazakh diaspora inthe countries of the near and far abroad. The history of our compatriots, who at one time, for various reasons, moved from the Kazakh land to other territories, cannot but worry none of us. After all, being in this foreign country, they make every effort to preserve their national identity, historical memory, basic values, especially national music.Especially the authors try to pay special attention to the spiritual potential of compatriots in neighboring Uzbekistan, Kyrgyzstan, Turkmenistan and not to ignore the traditional music of the Kazakhs of China, Mongolia, Iran
A new method for estimating carbon dioxide emissions from drained peatland forest soils for the greenhouse gas inventory of Finland
Authors: Alm Jukka , Wall Antti , Myllykangas Jukka-Pekka , Ojanen Paavo , Heikkinen Juha , Henttonen Helena M. , Laiho Raija , Minkkinen Kari , Tuomainen Tarja , Mikola Juha 
Published: September 2023

Abstract. In peatlands drained for forestry, the soil carbon (C) or
carbon dioxide (CO2) balance is affected by both (i) higher
heterotrophic CO2-C release from faster decomposing soil organic matter
(SOM) and (ii) higher plant litter C input from more vigorously growing
forests. This balance and other greenhouse gas (GHG) sinks and sources in
managed lands are annually reported by national GHG inventories to the
United Nations Climate Change Convention. In this paper, we present a
revised, fully dynamic method for reporting the CO2 balance of drained
peatland forest soils in Finland. Our method can follow temporal changes in
tree biomass growth, tree harvesting and climatic parameters, and it is built
on empirical regression models of SOM decomposition and litter input in
drained peatland forests. All major components of aboveground and
belowground litter input from ground vegetation as well as live trees and trees that died naturally
are included, supplemented by newly acquired turnover rates of woody
plant fine roots. Annual litter input from harvesting residues is calculated
using national statistics of logging and energy use of trees. Leaching,
which also exports dissolved C from drained peatlands, is not included. The
results are reported as time series from 1990–2021 following the practice
in the GHG inventory. Our revised method produces an increasing trend of annual
emissions from 0.2 to 2.1 t CO2 ha−1 yr−1 for the period
1990–2021 in Finland (equal to a trend from 1.4 to 7.9 Mt CO2 yr−1 for the entire 4.3 Mha of drained peatland forests), with a
statistically significant difference between the years 1990 and 2021. Across the
period 1990–2021, annual emissions are on average 1.5 t CO2 ha−1 yr−1 (3.4 Mt CO2 yr−1 for 2.2 Mha area) in warmer southern
Finland and −0.14 t CO2 ha−1 yr−1 (−0.3 Mt CO2 yr−1
for 2.1 Mha area) in cooler northern Finland. When combined with data on the
CO2 sink created by the growing tree stock, in 2021 the drained peatland forest
ecosystems were a source of 1.0 t CO2 ha−1 yr−1 (2.3 Mt CO2 yr−1) in southern Finland and a sink of 1.2 t CO2 ha−1 yr−1 (2.5 Mt CO2 yr−1) in northern Finland. We
compare these results to those produced by the semi-dynamic method used earlier
in the Finnish GHG inventory and discuss the strengths and
vulnerabilities of the new revised method in comparison to more static
emission factors.
COHESION OF PARAGRAPH IN EFL TEXTBOOK OF ESSAY WRITING CLASS OF UNIVERSITAS NEGERI MAKASSAR
Authors: Multazam Muhmmad Nurul , Korompot Chairil Anwar , Sakkir Geminastiti 
Published: September 2023

This research aimed to provide descriptive accounts of the use of paragraph cohesion in the textbook in learning materials for an essay writing class at UNM Makassar. This research employed a qualitative approach with descriptive data exposure. Qualitative research is research that aims to describe research results. This research analyzes and reveals various qualitative information with a detailed description through cohesion in this textbook. The research design used is descriptive-analytical. This design is a research design that describes the research objectively. Researchers observe in-depth and conduct an in-depth analysis of the object of research. In the application of this research design, the first thing the researcher did was to collect data and references relevant to the object of research, sort and categorize the data found, process the data, and then present the data objectively following the results of interruptions to the object of research conducted. The findings showed. The data analysis presentation consists of (1) cohesion, which includes grammatical cohesion (reference, substitution, ellipsis, and conjunction), and lexical cohesion, which includes repetition, synonym, antonym, hyponym, and collocation. In this textbook, cohesion has an influential role in the learning activity. It is suggested that it is significant to In the preparation of textbooks, it is recommended to study the presentation of the learning material to make it easier for students to understand. To facilitate students' understanding of the material, each paragraph of the learning material in the textbooks of the essay writing course at UNM should pay more attention to cohesion.
Keywords: Cohesion, Essay Writing, Qualitative Research.
РАЦИОНАЛЬНОЕ ЗЕМЛЕПОЛЬЗОВАНИЕ СЕЛЬСКОХОЗЯЙСТВЕННЫХ ЗЕМЕЛЬ: ПРОБЛЕМЫ И РЕШЕНИЯ
Authors: Бигараев О.К. , Костаков А.К. , Тагаев А. 
Published: September 2023

В данной статье приведены результаты применения эффективности и преимущества
метода планировки орошаемых среднезасоленных земель в условиях Туркестанской области.
Сегодня, когда идет глобальное экономическое развитие, распространение метода лазерной
планировки сельскохозяйственных земель является одним из современных и инновационных
технологических способов повышения продуктивности орошаемых угодий, особенно
поверженных к вторичному засолению почвы
Представленные технологии включают в себя практические разработки, направленные на
более эффективное использование водных и земельных ресурсов, а также минеральных удобрений
посредством лазерной планировки орошаемых засоленных земель. Основной целью планировки
земель в сельском хозяйстве является устранение неровности поверхности поля, которая
затрудняют проведение поливных и механизированных агротехнических мероприятий. Ровная
поверхность поля обеспечивает эффективное использование оросительных вод, их равномерное
распределение по полю и увлажнение почвы, способствует равномерному росту посевов за счет
заделки семян и равномерного внесения удобрений на одинаковую глубину и, следовательно,
дальнейшему равномерному росту растений и получению высокого урожая.
ТЕХНОЛОГИЧЕСКИЕ СВОЙСТВА ИНДООТБОРНЫХ ОБРАЗЦОВ СОРТОВ ХЛОПЧАТНИКА М-4011, М-4017
Authors: Махмаджанов Сабир , Дәуренбек Нұрман , Тагаев Аcанбай , Асабаев Багдаулет , Костак Олжас 
Published: September 2023

На данном этапе во всем мире перед селекционерами – семеноводами стоит задача улучшить селекцию и семеноводство хлопчатника на важнейшие хозяйственно – ценные признаки, используя весь арсенал наиболее прогрессивных методов и богатейший исходный материал, созданный на протяжении многих лет.
Основными высеваемыми сортами хлопчатника в Туркестанской являются сорт М-4011, М-4017, для сохранения чистосортности необходимо правильное проведение работ в семеноводческих питомниках. Сбор индоотборных образцов это начала работ в семенном питомнике для сохранения хозяйственно ценных и морфологических качества данного сорта. Индивидуальных сборов собрано по элите сортов М-4007 - 5612 шт., М - 4011 – 5840 шт. По оригиналу М - 4007 - 1237 шт., М - 4011 - 1367 шт. общее количество составило 14056 шт. Отобранные образцы прошли в лаборатории анализ по технологическим качествам и в последствии были отобраны образцы с высокими качествами волокна. В 2019 году по производству оригинальных и элитных семян по сортам М-4007, М-4011 было посеяно 2019 индоотборных образцов, отобранных и проанализированных из урожая 2018 года в количестве 3141 штук. В 2020 году по производству оригинальных и элитных семян по сортам М-4007, М-4011 было посеяно 2628 индоотборных образцов, отобранных и проанализированных из урожая 2019 года в количестве 5456 штук. В 2021 году посеяно 2019 индоотборных образцов, отобранных и проанализированных из урожая 2020 года в количестве 4500 штук.