bluuebunny/crossref_metadata_2025_split huggingface dataset:
MOSPPA: monitoring system for palletised packaging recognition and tracking
Authors: Castaño-Amoros Julio , Fuentes Francisco , Gil Pablo 
Published: February 2023

AbstractThe paper industry manufactures corrugated cardboard packaging, which is unassembled and stacked on pallets to be supplied to its customers. Human operators usually classify these pallets according to the physical features of the cardboard packaging. This process can be slow, causing congestion on the production line. To optimise the logistics of this process, we propose a visual recognition and tracking pipeline that monitors the palletised packaging while it is moving inside the factory on roller conveyors. Our pipeline has a two-stage architecture composed of Convolutional Neural Networks, one for oriented pallet detection and recognition, and another with which to track identified pallets. We carried out an extensive study using different methods for the pallet detection and tracking tasks and discovered that the oriented object detection approach was the most suitable. Our proposal recognises and tracks different configurations and visual appearance of palletised packaging, providing statistical data in real time with which to assist human operators in decision-making. We tested the precision-performance of the system at the Smurfit Kappa facilities. Our proposal attained an Average Precision (AP) of 0.93 at 14 Frames Per Second (FPS), losing only 1% of detections. Our system is, therefore, able to optimise and speed up the process of logistic distribution.
Unraveling disparate roles of organisms, from plants to bacteria, and viruses on built cultural heritage
Authors: Sanmartín Patricia , Bosch-Roig Pilar , Pangallo Domenico , Kraková Lucia , Serrano Miguel 
Published: February 2023

Abstract
The different organisms, ranging from plants to bacteria, and viruses that dwell on built cultural heritage can be passive or active participants in conservation processes. For the active participants, particular attention is generally given to organisms that play a positive role in bioprotection, bioprecipitation, bioconsolidation, bioremediation, biocleaning, and biological control and to those involved in providing ecosystem services, such as reducing temperature, pollution, and noise in urban areas. The organisms can also evolve or mutate in response to changes, becoming tolerant and resistant to biocidal treatments or acquiring certain capacities, such as water repellency or resistance to ultraviolet radiation. Our understanding of the capacities and roles of these active organisms is constantly evolving as bioprotection/biodeterioration, and biotreatment studies are conducted and new techniques for characterizing species are developed. This brief review article aims to shed light on interesting research that has been abandoned as well as on recent (some ongoing) studies opening up new scopes of research involving a wide variety of organisms and viruses, which are likely to receive more attention in the coming years.

Key points
• Organisms and viruses can be active or passive players in heritage conservation
• Biotreatment and ecosystem service studies involving organisms and viruses are shown
• Green deal, health, ecosystem services, and global change may shape future research
Alanine-based spacers promote an efficient antigen processing and presentation in neoantigen polypeptide vaccines
Authors: Aguilar-Gurrieri Carmen , Barajas Ana , Rovirosa Carla , Ortiz Raquel , Urrea Victor , de la Iglesia Nuria , Clotet Bonaventura , Blanco Julià , Carrillo Jorge 
Published: February 2023

AbstractNeoantigens are tumor-specific antigens that are mostly particular for each patient. Since the immune system is able to mount a specific immune response against these neoantigens, they are a promising tool for the development of therapeutic personalized cancer vaccines. Neoantigens must be presented to T cells by antigen presenting cells (APC) in the context of MHC-I or MHC-II molecules. Therefore, the strategy of vaccine delivery may have a major impact on the magnitude and quality of T cell responses. Neoantigen-based vaccines are frequently administered as a pool of individual synthetic peptides that induce mainly CD4+ T cell responses. MHC-I-mediated presentation and the elicitation of CD8+ T cell responses may be improved using DNA or RNA sequences that code for a unique long polypeptide that concatenates the different neoantigens spaced by linker sequences. When administered this way, the selection of the spacer between neoantigens is of special interest, as it might influence the processing and presentation of the right peptides by APCs. Here, we evaluate the impact of such linker regions on the MHC-I-dependent antigen presentation using an in vitro assay that assesses the MHC-I presentation of SIINFEKL, a H-2 Kb-restricted OVA peptide. Our results show that spacers used to generate epitope concatenates have a large impact on the efficiency of neoantigen processing and presentation by MHC-I molecules; in contrast, the peptide position and the flanking regions have a minimal impact. Moreover, linkers based on alanine residues promote a more efficient peptide presentation than the commonly used GGGS linker.
The Partner Perspective on Autologous and Implant-Based Breast Reconstruction
Authors: von Glinski Maxi , Holler Nikla , Kümmel Sherko , Wallner Christoph , Wagner Johannes Maximilian , Sogorski Alexander , Reinkemeier Felix , Reinisch Mattea , Lehnhardt Marcus , Behr Björn 
Published: February 2023

Abstract
Introduction
Partner involvement in the decision-making process concerning breast reconstruction (BR) after a breast cancer diagnosis may be very supportive for the patient. So far, no study evaluates partner satisfaction with the outcome after BR and the relationship to patient satisfaction. The aim of this study was to assess and compare partner satisfaction of BR with autologous tissue (ABR) and prosthetic implants (IBR), respectively, and compare it to patient-reported outcomes.

Patients and Methods
All patients undergoing ABR and IBR between January 2014 and December 2020 were asked to participate with their partners. Patient and partner satisfaction with breast reconstruction, overall outcome as well as patient’s perceived and self-reported psychosocial well-being were evaluated using the Breast-Q and a modified partner questionnaire, respectively.

Results
Fifty-three couples participated (IBR: n=30, ABR: n = 23). Patient and partner satisfaction with breast (r = 0.552), outcome (r = 0.465) as well as patient’s perceived and self-report psychosocial well-being (r = 0.495) were highly correlated with partners scoring significantly higher (p<0.001). In terms of partner satisfaction, both reconstructive procedures achieved satisfactory results. ABR scored higher in terms of softness of breast and how natural the breast feels to touch whereas IBR was rated superior evaluating the breast size.

Conclusion
Both reconstructive procedures achieve satisfactory results in terms partner satisfaction whereas patient’s psychosocial well-being was highly overestimated by their partners. Hence, partner inclusion in the regular psycho-oncological support might further sensitize them of the high psychological burden of a breast cancer diagnosis and therefore stabilize patients private support system.

Level of Evidence III
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
ENSO teleconnections in terms of non-NAO and NAO atmospheric variability
Authors: King Martin P. , Keenlyside Noel , Li Camille 
Published: February 2023

AbstractThe validity of the long-held understanding or assumption that El Niño-Southern Oscillation (ENSO) has a remote influence on the North Atlantic Oscillation (NAO) in the January–February–March (JFM) months has been questioned recently. We examine this claim further using atmospheric data filtered to separate the variability orthogonal and parallel to NAO. This decomposition of the atmospheric fields is based on the Principal Component/Empirical Orthogonal Function method whereby the leading mode of the sea-level pressure in the North Atlantic sector is recognised as the NAO, while the remaining variability is orthogonal (unrelated) to NAO. Composite analyses indicate that ENSO has statistically significant links with both the non-NAO and NAO variability at various atmospheric levels. Additional bootstrap tests carried out to quantify the uncertainty and statistical significance confirm these relationships. Consistent with previous studies, we find that an ENSO teleconnection in the NAO-related variability is characterised by lower-stratospheric eddy heat flux anomalies (related to the vertical propagation of planetary waves) which appear in November–December and strengthen through JFM. Under El Niño (La Niña), there is constructive (destructive) interference of anomalous eddy heat flux with the climatological pattern, enhancing (reducing) fluxes over the northern Pacific and Barents Sea areas. We further show that the teleconnection of extreme El Niño is essentially a non-NAO phenomenon. Some non-linearity of the teleconnections is suggested, with El Niño including more NAO-related variability than La Niña, but the statistical significance is degraded due to weaker signals and smaller sample sizes after the partitioning. Our findings have implications for the general understanding of the nature of ENSO teleconnections over the North Atlantic, as well as for refining methods to characterise and evaluate them in models.
Minimal access surgery for congenital diaphragmatic hernia: surgical tricks to facilitate anchoring the patches to the ribs
Authors: Mansour Sherif , Curry Joe , Blackburn Simon , Mullassery Dhanya , Thakkar Hemanshoo , Ballington Jennifer , Leukogeorgakis Stavros , Cross Kate , Giuliani Stefano , De Coppi Paolo 
Published: February 2023

Abstract
Objective
Minimal Access Surgery (MAS) for Congenital Diaphragmatic Hernia (CDH) repair is well described, yet only a minority of surgeons report this as their preferred operative approach. Some surgeons find it particularly difficult to repair the defect using MAS and convert to laparotomy when a patch is required. We present in this study our institutional experience in using an easy and relatively cheap methodology to anchor the patch around the ribs using Endo Close™. This device has an application in MAS for tissue approximation using percutaneous suturing.

Methods and technique
We retrospectively reviewed our database for patients undergoing MAS repair of CDH between 2009 and 2021. Outcome measures included length of surgery and recurrence rates after patch repair. Endo Close™ was used in all patients who required patch repair. We declare no conflict of interest and to not having received any funding from Medtronic (UK). The technique is as follows: (1) The edges of the diaphragm are delineated by dissection. When primary suture repair of the diaphragmatic hernia was unfeasible without tension, a patch was used. (2) The patch is anchored in place by two corner stitches at the medial and lateral borders. (3) The posterior border of the patch is fixed to the diaphragmatic edge by running or interrupted stitches. (4) For securing the anterior border, a non-absorbable suture is passed through the anterior chest wall and the patch border is taken with intracorporeal instruments. (5) Without making another stab incision, the Endo Close™ is tunnelled subcutaneously through the anterior chest wall. (6) The suture end is pulled through the Endo Close™ and the knot is tied around the rib. This procedure can be performed as many times as required to secure the patch.

Results
58 patients underwent MAS surgery for repair of CDH between 2009 and 2021. 48 (82%) presented with a left defect. 34 (58%) had a patch repair. The length of patch repair surgery for CDH ranged from 100–343 min (median 197). There was only one patient (3%) in the patch repair cohort that had a recurrent hernia, diagnosed 12 months after the initial surgery.

Conclusions
In our experience, MAS repair of CDH is feasible. We adopted a low threshold in using a patch to achieve a tension-free repair. We believe that the Endo Close™ is a cheap and safe method to help securing the patch around the ribs.
Efficacy and safety of double balloon catheter and dinoprostone for labor induction in multipara at term
Authors: Yuan Lu , Peng Jing , Yang Lijun , Zhao Yun 
Published: February 2023

Abstract
Purpose
The aim of this study was to comparatively assess the efficacy and safety of double balloon catheter (DBC) and dinoprostone as labor-inducing agents just for multipara at term.

Methods
A retrospective cohort study was conducted among multipara at term with a Bishop score < 6 who needed planned labor induction from January 1, 2020, to December 30, 2020 in Maternal and Child Health Hospital of Hubei province, Tongji Medical College, Huazhong University of Science and Technology. They were divided into DBC group and dinoprostone group, respectively. Baseline maternal data, maternal and neonatal outcomes were recorded for statistical analysis. Total vaginal delivery rate, rate of vaginal delivery within 24 h, rate of uterine hyperstimulation combined with abnormal fetal heart rate(FHR) were regarded as the primary outcome variables. The difference between groups was considered statistically significant when p value < 0.05.

Results
A total of 202 multiparas was included for analysis (95 women in DBC group vs 107 women in dinoprostone group). There were no significant differences in total vaginal delivery rate and rate of vaginal delivery within 24 h between groups. Uterine hyperstimulation combined with abnormal FHR occurred exclusively in dinoprostone group.

Conclusion
DBC and dinoprostone seem to be equally effective, while, DBC seems to be safer than dinoprostone.
Action–effect knowledge transfers to similar effect stimuli
Authors: Esser Sarah , Haider Hilde , Lustig Clarissa , Tanaka Takumi , Tanaka Kanji 
Published: February 2023

AbstractThe ability to anticipate the sensory consequences of our actions (i.e., action–effects) is known to be important for intentional action initiation and control. Learned action–effects can select the responses that previously have been associated with them. What has been largely unexplored is how learned action–effect associations can aid action selection for effects that have not previously associated with an action but are similar to learned effects. In two studies, we aimed to show that when presented new, unknown action–effects, participants select the responses that have previously been associated with similar action–effects. In the first study (n = 27), action–effect similarity was operationalized via stimuli belonging to the same or different categories as the previously learned action–effects. In the second study (n = 31), action–effect similarity was realized via stimuli that require comparable motor responses in real life. Participants first learned that specific responses are followed by specific visual effect stimuli. In the test phase, learned effect stimuli, new but similar effect stimuli and new but dissimilar effect stimuli were presented ahead of the response. The findings revealed that both learned effect stimuli and new similar effect stimuli affected response times, whereas new dissimilar effects did not. When a learned or a new similar effect was followed by a learned response, compared to an unlearned response, the responses were faster. We interpret these findings in terms of action–effect learning. The action–effect once bound to an action is used to select an action if a similar effect for which no action has been learned yet is presented. However, it is noteworthy that, due to our design, other explanations for the found transfer are conceivable. We address these limitations in the General Discussion.
Ecocide Before the International Criminal Court: Simplicity is Better Than an Elaborate Embellishment
Authors: Palarczyk Danuta 
Published: February 2023

AbstractIn 2021, with their proposals of a new definition of ‘ecocide’, the Independent Expert Panel for the Legal Definition of Ecocide (‘IEPLDE’) and the Promise Institute for Human Rights (‘UCLA’) Group of Experts reignited the discussion on expanding the International Criminal Court’s (‘ICC’ or ‘Court’) jurisdiction over the gravest instances of environmental degradation. The proposed definitions form part of the broader campaign towards the international criminalisation of ‘ecocide’ and its prosecution before the ICC. This discussion challenges such ambitions, arguing that, in its current form, the Court would be unable to produce environmentally-satisfactory results. It underscores that the human-centric fundaments of modern international criminal law (‘ICL’) prevent the ICC from fusing different approaches and values governing international environmental law (‘IEL’) into its institutional design. A middle-ground is proposed instead: rather than surrendering the pursuit of environmental justice before the ICC or risking a ‘symbolic’ revolutionisation, the focus should be re-oriented on maximising the ‘environmental’ potential of the current statutory framework. This approach aligns with the strive towards greater ‘internationalisation’ of international courts and tribunals, encouraging more eager analysis of their statutory provisions from multiple perspectives and in the context of a variety of cross-sectoral international law norms, objectives, principles, and approaches. Two possible directions for progression in that regard are proposed: (i) more resourceful translation of environmental realities into the substantive prohibitions of war crimes and (ii) more active reliance on and application of a ‘greened’ scope of Articles 21(3) and 7(1) of the Statute.
The European GeoMetre project: developing enhanced large-scale dimensional metrology for geodesy
Authors: Pollinger Florian , Baselga Sergio , Courde Clément , Eschelbach Cornelia , García-Asenjo Luis , Garrigues Pascual , Guillory Joffray , Hedekvist Per Olof , Helojärvi Tuomas , Jokela Jorma , Kallio Ulla , Klügel Thomas , Köchert Paul , Lösler Michael , Luján Raquel , Meyer Tobias , Neyezhmakov Pavel , Pesce Damien , Pisani Marco , Poutanen Markku , Prellinger Günther , Sauthoff Anni , Seppä Jeremias , Truong Daniel , Underwood Robin , Wezka Kinga , Wallerand Jean-Pierre , Wiśniewski Mariusz 
Published: February 2023

Abstract We provide a survey on the joint European research project “GeoMetre”, which explores novel technologies and their inclusion to existing surveying strategies to improve the traceability of geodetic reference frames to the SI definition of the metre. This work includes the development of novel distance meters with a range of up to 5 km, the realisation of optical multilateration systems for large structure monitoring at an operation distance of 50 m and beyond, and a novel strategy for GNSS-based distance determination. Different methods for refractivity compensation, based on classical sensors, on dispersion, on spectroscopic thermometry, and on the speed of sound to reduce the meteorological uncertainties in precise distance measurements, are developed further and characterised. These systems are validated at and applied to the novel European standard baseline EURO5000 at the Pieniny Kippen Belt, Poland, which was completely refurbished and intensely studied in this project. We use our novel instruments for a reduced uncertainty of the scale in the surveillance networks solutions for local tie measurements at space-geodetic co-location stations. We also investigate novel approaches like close-range photogrammetry to reference point determination of space-geodetic telescopes. Finally, we also investigate the inclusion of the local gravity field to consider the deviations of the vertical in the data analysis and to reduce the uncertainty of coordinate transformations in this complex problem.
NILRNN: A Neocortex-Inspired Locally Recurrent Neural Network for Unsupervised Feature Learning in Sequential Data
Authors: Van-Horenbeke Franz A. , Peer Angelika 
Published: February 2023

AbstractUnsupervised feature learning refers to the problem of learning useful feature extraction functions from unlabeled data. Despite the great success of deep learning networks in this task in recent years, both for static and for sequential data, these systems can in general still not compete with the high performance of our brain at learning to extract useful representations from its sensory input. We propose the Neocortex-Inspired Locally Recurrent Neural Network: a new neural network for unsupervised feature learning in sequential data that brings ideas from the structure and function of the neocortex to the well-established fields of machine learning and neural networks. By mimicking connection patterns in the feedforward circuits of the neocortex, our system tries to generalize some of the ideas behind the success of convolutional neural networks to types of data other than images. To evaluate the performance of our system at extracting useful features, we have trained different classifiers using those and other learnt features as input and we have compared the obtained accuracies. Our system has shown to outperform other shallow feature learning systems in this task, both in terms of the accuracies achieved and in terms of how fast the classification task is learnt. The results obtained confirm our system as a state-of-the-art shallow feature learning system for sequential data, and suggest that extending it to or integrating it into deep architectures may lead to new successful networks that are competent at dealing with complex sequential tasks.
Anthropogenic Pseudokarstic Depressions on Mount Bocskor (Bakony Region, Hungary)
Authors: Veress Márton , Unger Zoltán , Vetési-Foith Szilárd 
Published: February 2023

AbstractSurface forms above the mine (Ármin mine) of Mount Bocskor (Southern Bakony, Hungary) were examined. We made contour maps, plan maps, morphological maps and atectonic grike (cave) maps of some of the forms and their surroundings. We examined the distribution of the depth, length, elongation ratio in case of some depressions, the relation between the depth and the diameter of some depressions, the relationship between depression group directions and mine cut directions, the standard deviation of the direction differences of depression groups and of their depressions. The forms of the mountain related to surface mining can be separated to open and closed. The former are trenches and stairs, the latter are circular, elongated, and complex depressions. The formation of these forms can be related to the balancing movements of the vault over the mountain’s mine. At thin vault, stairs develop by collapses, while at the atectonic fissures of thicker vault, trenches and depressions are formed at the surface. In areas bordered by sinking (subsidence through) and downwardly cohesive faults, depression groups of diverse features are arranged in the marginal bands. Elongated depressions are formed at atectonic blocks bounded by dispersing faults in non-banded distribution. Where there is a superficial deposit, atectonic fissures can also be inherited directly by collapse to the surface and form depressions. They can also form indirectly over atectonic fissures by compaction, subsequent collapse and/or suffosion of the superficial deposit. The results of the study make it possible to analyse the material loss due to mining on the vault if the atectonic structures of the vault are partly or completely covered by superficial deposit.