bluuebunny/crossref_metadata_2025_split huggingface dataset:
Features of carbohydrate metabolism disorders in acute pancreatitis
Authors: Shcherbyuk A. N. , Morozov S. V. , Lobakov A. I. , Manuilov V. M. , Karpov N. V. , Mohov D. A. , Levitskaya A. N. , Levitskaya K. N. , Shalamova S. V. 
Published: May 2023

Introduction. Endocrine insufficiency of the pancreas manifests, as a rule, in the form of carbohydrate metabolism disorders.Methods and materials. The levels of insulin concentration were analyzed in 21 patients with various forms of acute pancreatitis with a degree of clinical severity on the APACHE II scale from 10 to 14 (12±2) and the levels of glucagon concentration in 16 patients with a degree of clinical severity on the APACHE II scale from 8 to 10 (9±1) on the 1st, 3rd and 7th day since the onset of disease, the dynamics of blood glycemia was observed in all patients.Results. As a result, despite the relatively normal blood glucose level in all observations compared with the control group, there was a decrease in insulin by more than 2 times, a decrease in glucagon by 1.5 times, the level of which increased by the outcome of the disease. In the presence of normoglycemia in all studied cases.Conclusions. The obtained data indicates that insufficiency of insulin and glucagon exists in all forms of AP. Relative normoglycemia is caused by absolute insulin insufficiency against the background of interstitial edema of the pancreas in AP. Correction of endocrine disorders in AP is a promising direction in the treatment of patients with various forms of AP.
Prolactin as a predictor of neuroendocrine recovery after transsphenoidal tumor removal in patients with pituitary apoplexy
Authors: Kurnukhina M. Yu. , Ashryapova D. Sh. , Semina E. V. , Gavrilov G. V. , Cherebillo V. Yu. 
Published: May 2023

Introduction. The risk of pituitary apoplexy is 5.4 times higher than the risk of hemorrhage into another intracranial tumor. Despite the fact that in 80 % of cases, hemorrhage into the pituitary adenoma is the first manifestation of the disease, the issues of neuroendocrine recovery, evaluation of the results of surgical treatment are insufficiently studied at present.Methods and materials. A clinical study of 72 patients with histologically confirmed diagnosis of pituitary adenoma was conducted. According to MRI of the brain with intravenous contrast, neuroimaging signs of pituitary apoplexy were found in all the studied patients. The studied patients were aged from 28 to 55 years, the average age of patients was 48.9±15.25 years (median 49 years). All the examined patients underwent surgical treatment – transsphenoidal endoscopic removal of pituitary adenoma; there were no emergency indications for surgical treatment among the examined patients. In the preop- erative and late postoperative periods, the relationship between the values of prolactin and other pituitary hormones with the parameters of neuroendocrine recovery was evaluated.Results. In patients with recurrent pituitary adenoma and pituitary apoplexy, suprasellar (χ2=8; r=0.005) and laterosellar growth (χ2=3.92; r=0.048) are significantly less common; reduced prolactin and ACTH values are more often detected after surgical treatment (p<0.05). It was revealed that with preoperative increased prolactin indices, general cerebral symptoms (r=–1; p=0) and visual disturbances (r=–0.982; p=0.28) are less common after surgery. In patients with ACTH-secreting pituitary adenoma after apoplexy, the totality of removal of Near Complete Gross Resection was more often observed (r=0.382; p=0.004).Conclusion. In patients with pituitary apoplexy before surgery, an increased prolactin index is one of the markers of regression of hypopituitary disorders in the postoperative period.
Сlinical features of hypertrophic cardiomyopathy depending on the age of onset of clinical manifestations and the presence of cardiometabolic risk factors
Authors: Davydova V. G. , Baranova Е. I. , Bezhanishvili T. G. , Krutikov A. N. , Poliakova A. A. , Pyko S. A. , Gudkova A. Ya. 
Published: May 2023

The objective was to study the clinical features of symptomatic hypertrophic cardiomyopathy (HCM) depending on the age of onset and the presence of cardiometabolic risk factors.Methods and materials. From 2014 to 2020, 250 patients were examined, 100 patients with symptomatic HCM aged 18 to 86 years were included in the study.Results. The incidence of arterial hypertension (AH), obesity, and angina syndrome was significantly higher in patients with HCM aged 45 years and older. The patients with HCM and associated obesity had greater left ventricular end-diastolic dimension and left antero-posterior size regardless of the age of onset of clinical manifestations. The young patients with HCM and associated obesity had more often AH. Patients with HCM with the disease onset ≥ 45 years of age and associated obesity had greater left ventricular posterior wall thickness, left ventricular end-diastolic dimension index. In this group of patients, pulmonary hypertension was more often diagnosed.Conclusion. Obesity and other cardiometabolic risk factors are predictors of the progressive course of HCM, which points the need for their prevention and timely correction.
Hybrid interventions on cerebral dural arteriovenous fistulas with isolated segment of the venous sinus
Authors: Sergeev A. V. , Kiskaev A. I. , Savello A. V. , Chemurzieva F. A. , Cherebillo V. Yu. 
Published: May 2023

Introduction. In most cases, dural arteriovenous fistulas of the brain can be effectively treated endovascularly. However, rare fistulas with an isolated segment of the venous sinus may be difficult to treat surgically. Hybrid surgical interventions (combination of open surgical access to the sinus and puncture embolization in hybrid operating room) can significantly increase the effectiveness of surgical treatment of patients with this pathology.The objective was to improve the results of surgical treatment of patients with cerebral dural arteriovenous fistulas with isolated segment of the venous sinus by using a hybrid surgical intervention.Methods and materials. 2 surgical interventions were performed using microsurgical and endovascular methods. Surgical interventions were made in hybrid operating room.Results. Radical occlusion of dural arteriovenous fistulas was achieved in both cases. The postoperative period was favorable in both cases with positive dynamics in the neurological status.Conclusions. Hybrid interventions combining microsurgical and endovascular methods make it possible to achieve radical occlusion of “complex” cerebral dural arteriovenous fistulas with isolated segments of the venous sinus.
Possibilities of post-COVID medical rehabilitation in the context of the ongoing pandemic
Authors: Belash V. A. , Korshunova A. A. , Bilichenko E. B. , Lamden Ju. A. , Kulikov A. N. 
Published: May 2023

Introduction. Effective and available rehabilitation methods are necessary in the context of the ongoing pandemic of COVID-19 (CoronaVirus Disease 2019).The objective was to develop a personalized rehabilitation program for patients who have undergone COVID-19 based on the proven effectiveness of methods.Methods and materials. Three months after COVID-19, 855 patients were examined by the method of standardized phone interview, according to the rehabilitation routing scale (RRS). 200 patients have got through the 10-days inpatient rehabilitation course. Breathing exercises, exercise regimen designed to strengthen basic muscles groups, Nordic walking were used. The physical activity level, heart rate and saturation (SpO2) have been monitored by wearable devices (fitness-trackers) during 3 months.Results. Inpatient rehabilitation was required for 1 % of patients, outpatient – 19 %. 42 % did not need rehabilitation, but they had respiratory symptoms and decreased exercise tolerance. There was an improvement in flexibility, muscle strength; the duration of breath holding, 6-minutes walk test, exercise tolerance test; reducing the severity of shortness of breath (mMRC scale) and respiratory symptoms (САТ scale). The achieved level of daily physical activity was maintained for 3 months after the end of the rehabilitative program.Сonclusion. Using the rehabilitation routing scale in the post-COVID period allows stratifying patients according to the degree of need for rehabilitation. Clinically significant and persistent positive effect in most patients can be achieved by physiotherapy methods during 10-days course. Wearable devices of monitoring biometric data are useful additional instruments for monitoring recovery after COVID-19.
Deciding on the optimal treatment protocol for patients with severe unstable pelvic trauma
Authors: Gvenetadze V. V. , Dulaev A. K. , Tsed A. N. 
Published: May 2023

Pelvic trauma caused by high-energy forces are accounting for 3 % to 8 % of all traumatic fractures. These are often accompanied by other life-threatening injuries that is a serious tactic problem. There are many publications on the advantages and disadvantages of multi-stage treatment with the Damage Control Orthopedics protocol and Early Total Surgical Care. However, the most difficult category was those who are in a borderline or hemodynamically unstable state.Their treatment is often complicated by acute respiratory distress syndrome (ARDS) and multiple organ failure syndrome (MOFS). The reliable risk assessment, associated with the implementation of a single-stage or multi-stage treatment protocol in patients with unstable pelvic injury, is not sufficient, and surgeon has to choose the treatment protocol based only on own experience.The objective was to analyze the results of using single-stage and multi-stage treatment protocols for patients with unstable pelvic trauma and identify insufficiently researched aspects of each of them.
The Managing Hotel Employees Achieving Wow!: A Conceptual Paper
Authors: Hastjarjo Kelik 
Published: May 2023

Managing Hotel Employees Achieving Wow! is a conceptual model. The process starts when employees have to serve customers with the best culture for customers. If customers start off on the right foot. It is an experience where customers feel the pleasure of interacting with employees. By linking each activity category together into a simpler system, this model creates many opportunities to repeat the cycle through customer satisfaction and loyalty.

Keywords : hospitality culture, hospitality people, hospitality service cycle
Study of Antibacterial, Antioxidant Activity and Biochemical Parameters of Different Honey Samples
Authors: Hussein Jian Lateif , Ahmed Akhter Ahmed , Raheem Dotsha Jaleel 
Published: May 2023

The present study was undertaken to determine and compare the antibacterial and biochemical characteristics of honey samples from Kurdistan region in Iraq and Arabian Gulf region. Sixteen honey samples of mixed floral origins from both regions were analysed and compared. Antibacterial activity of the honey samples was investigated against five clinical pathogenic bacteria: Acinetobacter baumannii, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi and Staphylococcus aureus by agar dilution method. Both sample sets showed differential biochemical characteristics and potential functional properties such as antioxidant and antimicrobial properties. All measured parameters were within accepted ranges. However, significant differences were found in mean±SE levels of conductivity and pH, diastase activity, TPC and DPPH activity between the two sample groups with KRI samples showing more desirable qualities. Other parameters such as water content, total acidity, total and reducing sugars, sucrose and HMF showed no significant difference. The results of antibacterial activity indicated that KRI honey is more effective than AG honey against the tested pathogenic bacteria.
George Henry Wyatt (1828-1883): Agent, Shipowner, Entrepreneur, and One-Man Naval Department
Authors: Lewis Walter , Sarty Roger 
Published: May 2023

This is a first attempt to trace the life of George Henry Wyatt. He has previously been known only for his work procuring and administering the civilian steamers provided by Canada for arming and operation by the Royal Navy on the Great Lakes-St. Lawrence frontier during the Fenian crisis of 1866-1871. The research presented here shows that by the 1860s he had become a significant member of the Toronto business community. Among several enterprises, he was particularly active as a ship owner and agent for steamship and railway lines. This experience accounted for his selection by the government to organize the flotilla of steamers for the Royal Navy, and his success in that role. He was, however, not able to overcome the effects in Canada of the international economic downturn of the 1870s. He died in a new venture, to promote immigration to the newly opening Canadian west.
Cet article est une première tentative de retracer la vie de George Henry Wyatt. Par le passé, il n’était connu que pour son travail d’acquisition et d’administration des bateaux à vapeur civils fournis par le Canada pour appuyer les efforts d’armement et d’exploitation de la Marine royale sur la frontière des Grands Lacs et du Saint-Laurent pendant la crise des Féniens de 1866-1871. Les recherches présentées ici indiquent que, dans les années 1860, Wyatt était devenu un membre important du milieu des affaires de Toronto. Entre autres entreprises, il était particulièrement actif en tant que propriétaire de navires et agent de compagnies de navigation et de chemin de fer. En raison de son expérience, le gouvernement l’a choisi pour organiser la flottille de bateaux à vapeur pour le compte de la Marine royale, où il a joué un rôle particulièrement efficace. Par contre, il n’a pas été en mesure de surmonter les effets au Canada du ralentissement économique international des années 1870. Wyatt est décédé alors qu’il travaillait sur un nouveau projet, la promotion de l’immigration dans l’Ouest canadien.
TOLEDO: Accelerated Maestro GUI molecular dynamics simulations
Authors: Carmena-Bargueño Miguel , Martínez-Cortés Carlos , Banegas-Luna Antonio Jesús , Pérez-Sánchez Horacio 
Published: May 2023

Classical Molecular Dynamics (MD) simulate the dynamical evolution of biological systems at the atomic level. Using MD in conjunction with high-performance computing (HPC) architectures we can evaluate the possible interactions between a ligand library against one protein target to find a drug that can influence a protein target to cure a disease. Simultaneously we can also obtain information about their dynamical evolution One of the main software of MD is Desmond, which uses Maestro to set up, run and analyze MD with a graphical interface (GUI), allowing it to be used by non-expert users. However, using the GUI, users can typically run only one short (less than 1000 ns) MD simultaneously. Our work aims to create a method/protocol to run several MD simultaneously on a remote HPC cluster within Maestro-Desmond. In this work, we provide a method called TOLEDO (Throughput Optimization of Ligand-Protein systems Exploration through Dynamics simulation in Optimized HPC systems) to overcome such limitations and run several MD simultaneously time. Also, TOLEDO is independent of the time limitation of many clusters, the only limitation is the storage space that users have in the cluster. To run TOLEDO, first, we prepare/set up the protein-ligand complex before running MD via Maestro GUI. Next, we run the main script of TOLEDO to run several MD in a supercomputer such as Turgalium of CIEMAT (https://www.ceta-ciemat.es/) or SAGA (https://documentation.sigma2.no/hpc_machines/saga.html), when the MD are finished. TOLEDO run the analysis. Finally, the results obtained by users are the reports and the graphics, which are very simple to interpret. In summary, TOLEDO is a tool that allows researchers to run MD with higher throughput than the Maestro GUI.
Arquitecturas Precolombinas: Representar y Habitar el pasado.
Authors: Montalvo Puente Carlos Eduardo 
Published: May 2023

Resumen: Este artículo presenta un acercamiento a los procesos de investigación y curaduría desarrollados para la exhibición “ Arquitecturas Precolombinas: representar y habitar el pasado”. Esta exhibición se ha planteado como objetivo el acercamiento de los públicos contemporáneos a las relaciones entre personas, estructuras y paisajes, es decir al concepto de habitar, a través de las diferentes miradas de la arquitectura precolombina a través del tiempo. Para lograr su objetivo, la exhibición plantea un diálogo entre piezas arqueológicas, documentos, narraciones y testimonios, incluyendo datos de investigaciones recientes con tecnologías de punta.
Abstract: This paper aims to present the research and curatorship processes developed for the exhibition “Pre-Columbian Architectures: Represent and Inhabit the Past”. This exhibition points to create a connection between the contemporary public and the interrelation of people, structures and landscapes enclosed in the concept of inhabit, by the views of the pre-columbian architectures across time. To achieve his goal, the exhibition proposes a dialog between archaeological artifacts, documents, narrations and testimonies, including recent investigation data collected with recent technologies.
Aceh Traditional Culinary Kuah Pliek U: How it Sustains Eco-Lexicon Diversity
Authors: Zurriyati Zurriyati , Yuliza Yuliza , Zulfikar Teuku , Perangin-angin Alemina Br. 
Published: May 2023

"Kuah Pliek" is the famous Acehnese cuisine that utilizes most ecological materials. However, only a few researchers have discussed the sustainability of the lexicon contained within the cuisine from an eco-linguistics perspective. This study focuses on Aceh's traditional cuisine, "Kuah Pliek U" (KPU), to assess the raw materials' eco-lexicon diversity and the Acehnese's knowledge of the identified eco-lexicon. This study employed a qualitative research design to address the problems in which data collection included in-depth interviews, Focus Group Discussions (FGDs), passive and active observation, and the examination of documents such as research reports and journal articles. The analysis of data then used a qualitative interactive model. The result demonstrates that the number of the eco-lexicon within KPU is about 35 – 40, as same as its total of raw materials and ingredients. It consists of biotic and abiotic, with plants comprising the majority. Linguistically, the lexicon belongs to the noun class, but semantically, it can be divided into nouns, prepositional eco-lexicons, and nouns and conjunction. This study also reveals that Acehnese knowledge of KPU has decreased, despite its continued popularity in Aceh society. It means that the existence of three dimensions that influence language sustainability cannot guarantee that local people's cultural knowledge will remain intact.
Dampak Perusakan Antropogenik Terhadap Sedimentasi dan Erosi Pada Hutan Lindung Wosi Rendani Di Kabupaten Manokwari
Authors: Mahmud  
Published: May 2023

Masyarakat yang mendiami sekitar hutan dalam menunjang kehidupan tidak terlepas dari interaksi dengan hutan, tak terkecuali dengan hutan lindung yang memicu kejadian erosi, sedimentasi, banjir dan longsor. Penelitian bertujuan untuk mengidentifikasi perusakan antropogenik Hutan Lindung Wosi Rendani (HLWR) dan dampak yang ditimbulkan terhadap sedimen dan erosi. Penelitian dilakukan melalui survey dan analisis data dengan skoring. Kepala KPHL, polisi hutan dan pensiunan pegawai Dinas Kehutanan dipilih dalam pengambilan contoh dengan segaja. Hasil penelitian menunjukkan aktifitas antropogenik di area HLWR meliputi perambahan hutan, penebangan liar, perladangan berpindah dengan cara membakar, pengambilan tanah dan galian C, alih fungsi ke kawasan terbangun. Aktivitas antropogenik berdampak terhadap peningkatan sedimen dari tinggi menjadi sangat tinggi dan erosi berkategori sangat tinggi. Peningkatan sedimen dan erosi disebabkan oleh penyusutan dan perusakan HLWR sekarang tersisa 26% yang jika tidak segera dikelola dengan baik akan menjadi pemicu penyebab banjir maupun banjir bandang.
PELATIHAN PEMBUATAN LAHAN PERTANIAN PEPAYA CALIFORNIA DENGAN IRIGASI TETES DI DESA SELENGEN KABUPATEN LOMBOK UTARA
Authors: Negara I Dewa Gede Jaya , Wiratama Kadek , Yasa I Wayan , Saidah Humairo , Supriyadi Anid , Suparjo Suparjo 
Published: May 2023

Pengembangan pertanian di lahan kering,sangat menjanjikan jika masyarakat mau tekun melakukan pertanian dengan lebih intensif, dan untuk mendorong kepekaan masyarakat tentang potensi lahannya perlu diberikan pelatihan-pelatihan terkait dengan pemanfaatan lahannya. Dusun Tampes merupakan wilayah desa Selengan yang memiliki potensi lahan kering yang perlu dikembangkan, dengan adanya lahan yang banyak tidak tergarap perlu dimotivasi untuk mau melakukan usahatani pada lahan tersebut. Pengabdian ini bertujuan untuk memberikan pelatihan pembuatan lahan untuk penanaman papaya California pada masyarakat dusun Tampes yang berdomisili di sekitar sungai. Dengan harapan lahan tanam yang dibuat nantinya dapat dilanjutkan dengan penanaman bibit papaya, untuk membantu ekonomi masyarakat setempat, karena tanaman ini mempunyai masa panen cukup panjang dan harga jual buanya cukup bangus. Untuk itu karena lahan ini berpasiran sehingga sangat boros air maka perlu diinisiasi penggunaan air irigasi yang efisien seperti sistem tetes. Untuk hal tersebut maka pelatihan oleh tim Unram dilakukan dalam jangka waktu 2 minggu yang mencakup survey lapangan, persiapan pelatihan, pelaksanaan pelatihan dan evaluasi. Pelatihan terdiri dari pembersihan lahan, pembuatan petak lahan dan bedengan, dan pembuatan lubang tanam. Berdasarkan hasil pelatihan diketahui bahwa warga telah mampu membuat lahan tanam papaya. Sedangkan evaluasinya adalah keberhasilan dari masing-masing peserta alam membuat lahan tanam. Berdasarkan hasil pelatihan bahwa peserta telah berhasil melakukan pembuatan lahan papaya dengan luasan seluas sekitar 2 ha dengan jumlah warga berpartisipasi sebanyak 26 orang. Dengan fakta ini peserta telah berhasil dilatih untuk membuat lahan awal untuk penanaman papaya California, yang akan dilakukan lebih lanjut. Dengan berhasilnya kegiatan ini, maka tim memberi arahan agar nantinya dapat dilanjutkan dengan pengisian pupuk kompos masing-masing sehingga bisa dilakukan penanamn bibit papaya di lahan masing-masing
Pengaruh Sampah Plastik Terhadap Kelimpahan Semai Mangrove di Tambak Wedi Surabaya
Authors: Megawati Mutiara Gusti  , Nirmala Idha Wijaya  , Mahmiah  
Published: May 2023

Salah satu kebiasaan masyarakat yang susah dihilangkan adalah membuang sampah. Sampah yang dibuang oleh masyarakat di kawasan mangrove akan terkena air laut saat pasang dan akhirnya menyebar luas, dan ketika air laut sedang surut sampah-sampah plastik tersebut akhirnya tersangkut atau bahkan menimpa semai mangrove dan berakibat banyak semai mangrove yang patah karena tidak kuat menahan sampah tersebut, dan sampah plastik yang tersangkut pada mangrove juga dapat menghalangi sinar matahari yang dibutuhkan mangrove untuk berkembang biak. Padahal fungsi mangrove sangatlah penting seperti mencegah erosi, abrasi, tempat tinggal bagi beberapa biota dan masih banyak lagi. Berdasarkan latar belakang tersebut peneliti ingin mengetahui pengaruh sampah plastik terhadap kelimpahan semai mangrove. Adapun tujuan penelitian ini untuk mengetahui pengaruh tutupan sampah plastik terhadap pertumbuhan semai mangrove dan mengetahui pengaruh sampah plastik terhadap kelimpahan semai mangrove di Tambak Wedi Surabaya. Metode yang digunakan dengan mengambil sampling vegetasi pada sebuah transek berukuran 2x2 m untuk semai, 5x5 m untuk pancang, dan 10x10 m untuk pohon pada tempat yang berbeda serta menghitung luasan tutupan sampah plastik di tiap stasiun. Dari hasil observasi diperoleh data di tiap stasiun menunjukkan bahwa sampah plastik yang menutupi area mangrove jumlah sampah plastik di tiap stasiun 139,4 – 144,6 m2, kerapatan mangrove di 3 stasiun adalah 14.700 ind/ha dan untuk kerapatan semai rata- rata di tiap stasiun sebesar 26.666 ind/ha. Jika dilihat dari kriteria baku kerusakan mangrove maka kondisi kerapatan semai mangrove di daerah tambak wedi ini tergolong baik.