bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of force and moment tensor estimations of subevents during the 2022 Hunga–Tonga submarine volcanic eruption
Authors: Thurin J , Tape C 
Published: August 2023

SUMMARYThe 2022 January 15 Hunga–Tonga submarine volcanic eruption was unprecedented in the modern era for its size, in terms of its plume height and atmospheric waves, including sound. Global seismic stations recorded maximal radiated energy during 30 min of the plume-forming phase of the eruption (04:00 to 04:30 UTC), with the largest subevents occurring over a 5-min interval starting at 04:15:17 UTC. Here, we consider two simple point-source models—force and moment tensor—and separately consider the single main subevent and the sequence of four subevents. Estimation of source models for the first subevent in the sequence is achieved with a complete search of model parameter space to find the global minimum of a waveform misfit function (body or surface waves). We performed 25 runs to explore the impact of depth, source model (force or moment tensor), wave type (body or surface), and component (vertical, radial, and transverse) on the waveform fits and estimated best-fitting source. Visualization of the misfit function reveals complex trade-offs among model parameters, highlighting the importance of characterizing uncertainties and parameter trade-offs. The four-subevent source model has up to 28 model parameters and requires an efficient search algorithm to find the best-fitting source. For this, we use the covariance matrix adaptation evolution strategy implemented on a high-performance computing cluster. The 10 four-subevent runs for each source model return sequences of subvertical downward forces and explosive-like moment tensors for each subevent. Our results show that these two simple source models provide comparable fits to regional and global seismic waveforms and that the source types for each subevent—either force direction or moment tensor source type on the eigenvalue lune—are similar enough to each other to consider that the subevents originate from the same process. Our estimation of the source mechanisms, sizes, and relative timing should benefit a physical interpretation of the eruption sequence.
Predictive Factors for Efficacy of Oral Tacrolimus Induction Therapy in Moderate to Severe Ulcerative Colitis Patients: Large Multicenter Retrospective Cohort Study
Authors: Oshima Naoki , Hiraoka Sakiko , Hayashi Ryohei , Takahashi Sakuma , Ishii Manabu , Hashimoto Shinichi , Yashima Kazuo , Igawa Shoko , Inokuchi Toshihiro , Ueno Yoshitaka , Inaba Tomoki , Matsumoto Hiroshi , Kawashima Kousaku , Takami Taro , Isomoto Hajime , Shiotani Akiko , Tanaka Shinji , Ishihara Shunji 
Published: August 2023

Abstract

Background
Tacrolimus (TAC), a calcineurin inhibitor, is used for remission induction therapy in patients with moderate to severe ulcerative colitis (UC), with short-term efficacy and related predictive factors shown in previous cohort studies. However, most studies reported data for only a limited number of patients enrolled from a single center. We performed a large multicenter retrospective cohort study to identify factors related to prediction of clinical remission in UC patients treated with oral TAC.

Methods
The medical records of patients with moderate to severe UC treated with oral TAC as induction therapy at 7 institutions between April 2009 and March 2017 were retrospectively reviewed.

Results
A total of 216 patients who received TAC for induction were analyzed, of whom 123 (56.9%) showed clinical remission at week 12. Logistic regression analysis indicated that previous or current use of antitumor necrosis factor (TNF)-α antibodies (odds ratio [OR], 0.259; P = .006), and concomitant treatment with 5-aminosalicylate (5-ASA) at the baseline (OR, 0.268; P = .005) were independent predictive factors correlated with failure of clinical remission, whereas higher levels of C-reactive protein (OR, 1.124; P = .014) predicted achievement of clinical remission.

Conclusions
Results of this multicenter study clearly indicate the efficacy of TAC induction therapy for patients with moderate to severe UC. Notably, previous or current use of anti-TNF-α antibodies was associated with poor achievement of clinical remission by week 12.
Synergy Degree Evaluation in the Development of Intelligent Construction and Construction Industrialization—A Case Study of Shenyang, China
Authors: Wu Jiangxuan , Li Lihong 
Published: August 2023

Abstract
In recent years, China’s construction industry has faced looming problems such as sloppy production methods and environmental pollution. Then the initiative of ‘synergistic development of intelligent construction and construction industrialization (ICCI)’ was proposed, which brings new opportunities for the transformation and upgrading and high-quality development of the construction industry. However, the synergy degree in the development of ICCI cannot be measured by the senses. Therefore, this study is devoted to quantitative analysis of the synergy degree in the development of ICCI by establishing a mathematical model. The concept of the synergy degree in the development of ICCI is defined based on synergetics. CiteSpace software is used to determine the five basic elements of talent, technology, information, environment and policy for the synergistic development of ICCI. Based on this, building a mechanism for synergistic development of ICCI with the Driving Force-State-Response (DFSR) model. Establishing an evaluation index system for the synergy degree in the development of ICCI through expert interviews. Then, combining entropy power method and coupling coordination model to empirically analyse the synergy degree in the development of ICCI in Shenyang. The results show that Shenyang is currently at the stage of high-level coupling and high-quality synergy, which is consistent with the actual development. It is also confirmed that the evaluation system of the synergy degree in the development of ICCI is scientific and reasonable. Finally, this study summarizes the suggestions for different levels of the synergy degree in the development of ICCI, which provides a reference for each region to better promote the synergistic development of ICCI.
Discovery and characterization of a novel PKD-Fn3 domains containing GH44 endoglucanase from a Tibetan metagenomic library
Authors: Lyu Yunbin , Luo Hao , Chai Shumao , Zhang Ying , Fan Xinyu , Wang Shaochen , Feng Zhiyang 
Published: August 2023

Abstract

Aims
To explore novel microbial endoglucanases with unique properties derived from extreme environments by using metagenomics approach.

Methods and results
A Tibetan soil metagenomic library was applied for screening cellulase-active clones by function-based metagenomics. The candidate genes in the active clones were identified through bioinformatic analyses and heterologously expressed using an Escherichia coli system. The recombinant endoglucanases were purified and characterized using enzyme assays to determine their bioactivities, stabilities, substrate specificities, and other enzymatic properties. A novel endoglucanase gene Zfeg1907 was identified, which consisted of a glycoside hydrolase family 44 (GH44) catalytic domain along with a polycystic kidney disease (PKD) domain and a fibronectin type Ⅲ (Fn3) domain at the C terminal. Recombinant enzyme ZFEG1907 and its truncated mutant ZFEG1907t (ΔPKDΔFn3) were successfully expressed and purified. The two recombinants exhibited catalytic activities toward carboxymethyl cellulose, konjac glucomannan (KGM), and lichenan. Both enzymes had an optimal temperature of 50°C and an optimal pH value of 5.0. The catalytic activities of both recombinant enzymes were promoted by adding Zn2+ and Ca2+ at the final concentration of 10 mM. The Km value of ZFEG1907 was lower, while the kcat/Km value of ZFEG1907 was higher than those of of ZFEG1907t when using carboxymethyl cellulose, KGM, and lichenan as substrates. Structure prediction of two recombinants revealed that PKD-Fn3 domains consisted of a flexible linker and formed a β-sandwich structure.

Conclusions
A novel endoglucanase ZFEG1907 contained a GH44 catalytic domain and a PKD-Fn3 domain was characterized. The PKD-Fn3 domains were not indispensable for the activity but contributed to the enzyme binding of the polysaccharide substrates as a carbohydrate-binding module (CBM).
Economic, health, and environmental burden of Tuta absoluta (Lepidoptera: Gelechiidae), in tomato production in Kenya and Uganda
Authors: Chepchirchir Fridah , Muriithi Beatrice Wambui , Langat Jackson , Ndlela Shepard , Mohamed Samira Abuelgasim , Khamis Fathiya 
Published: August 2023

Abstract
The negative effects of pest infestation on agricultural production cannot be underestimated. There have been several efforts to control these pests, chiefly through the use of synthetic pesticides. However, the continuous use of the chemicals causes pest resistance and resurgence and presents high human and environmental risks. This study examines the economic, health, and environmental impacts of Tuta absoluta (Meyrick 1917), an economically important pest in tomato production, among smallholder farmers in selected counties in Kenya and Uganda. Economic Impact Quotient and gross margin analysis were used on data obtained from a random sample of 316 and 345 tomato growers in Kenya and Uganda, respectively. The results show a significant impact of T. absoluta on tomato production in both countries. On average, the tomato growers earned a gross income of $38,123 and $11,627 in Kenya and Uganda, respectively, with synthetic chemicals for the management of T. absoluta contributing 66–78% of the cost of production. The opportunity cost lost due to forgoing pesticide for management of the pest, and instead replacing it with an integrated pest management package was valued between $8 and $646 in Kenya and $895 in Uganda, respectively, using net present value through the most pessimistic scenario, while benefit–cost ratio was $1 and $5 in Kenya and Uganda, respectively.
Growing media is the major source of damaging population of Systena frontalis (Coleoptera: Chrysomelidae) in ornamental plant nurseries
Authors: Arshad Rehan , Chong Juang Horng , Del Pozo-Valdivia Alejandro I , Joseph Shimat V 
Published: August 2023

Abstract
Systena frontalis (F.) (Coleoptera: Chrysomelidae) is a serious pest of ornamental shrubs in containerized ornamental plant nurseries in the central and eastern United States. Adult S. frontalis cause numerous shot holes on foliage, rendering ornamental plants unmarketable. Growing media in plant containers is an overwintering site of S. frontalis, but the extent to which adults emerging from the growing media can damage the plants is unclear. Experiments were conducted on panicled hydrangea (Hydrangea paniculata Siebold) in Georgia, North Carolina, and Virginia nurseries in the spring of 2021 and 2022 to answer this question. The treatments were (i) canopy caged, (ii) whole-plant caged, and (iii) noncaged hydrangea plants. In all 3 states, beetle abundance and feeding damage found on caged (whole plant) and noncaged plants were significantly greater than those on plants where only the canopy was caged. In most sites and years, beetle abundance and feeding damage were not significantly different between the noncaged plants and those where the canopy and containers were caged, suggesting that the majority of S. frontalis emerged from the growing media and the majority of damage suffered by the hydrangea plants were caused by beetles emerging from the containers. Because growing media contributed to a significant proportion of the S. frontalis population in a nursery, treatment targeting larvae in the growing media should be a critical component of a holistic management plan against S. frontalis.
The first report of surgery for gynecological diseases using the hinotori™ surgical robot system
Authors: Togami Shinichi , Higashi Takuro , Tokudome Akio , Fukuda Mika , Mizuno Mika , Yanazume Shintaro , Kobayashi Hiroaki 
Published: August 2023

Abstract

Objective
This study aimed to report the first surgery for gynecological diseases using a new robotic platform, the hinotori™, and validate its feasibility in clinical settings.

Methods
The world’s first robot-assisted total hysterectomy for a gynecological ailment was carried out at Kagoshima University Hospital in December 2022 utilizing the hinotori™ surgical robot system. Eleven other patients then underwent comparable procedures. The surgical team was certified to execute the procedure and had undergone official hinotori™ training.

Results
Preoperative diagnoses indicated five cases of endometrial cancer, four cases of uterine myoma and one case each of atypical endometrial hyperplasia, uterine adenosarcoma and high-grade cervical intraepithelial neoplasia. Median age and body mass index were 51 (range: 38–70) years and 26.9 (range: 17.3–33.3) kg/m2, respectively. Median roll-in, cockpit and operation times were 15 (range: 10–18), 161 (range: 110–225) and 214 (range: 154–287) min, respectively. The median blood loss was 22 (range: 7–83) mL and conversion to laparotomy was not allowed. Only one patient had postoperative pelvic region infection. The median length of hospital stay was 6 (range: 4–10) days.

Conclusion
Based on our experience with presented 12 cases, robotic surgery with the hinotori™ is a feasible technique of minimally invasive surgery for gynecological diseases.
Life history variation of the Hairy-tailed Akodont (Necromys lasiurus, Rodentia, Sigmodontinae) in the Caatinga biome of northeastern Brazil
Authors: Sobral Gisela , de Oliveira João Alves 
Published: August 2023

Abstract
Rodents are notable for their unique life history traits that render a fast-breeding capacity. Their short generation times allow local adaptations to appear, and several studies have tried to understand if—and how—geographical variables influence local adaptation in life history traits. We compared demographic and life history traits of the Neotropical cricetid Necromys lasiurus based on 7,400 museum specimens collected daily and simultaneously over 5 years at several sites in the Caatinga biogeographic domain subject to heterogeneous geographic and climatological variables. This sample, assembled by the National Plague Service between 1951 and 1955, includes skulls, skins, and individual specimen data currently deposited in the Museu Nacional (Rio de Janeiro, Brazil). Based on this material, we analyzed population fluctuation, breeding season, sexual size dimorphism, sexual maturity, and litter size. We also hypothesized that geographic variables (elevation, rainfall, temperature, longitude, and latitude) influence key life history traits, such as size at birth and litter size. Overall, N. lasiurus showed plastic reproductive patterns, with few traits shared among populations. Notably, there is strong seasonal variation in population fluctuation patterns, breeding events clumped in early dry season and old individuals distributed throughout all the year, as has been seen for populations in other biomes. Geography had no influence on size at birth but litter size was explained by the interaction between maternal weight and geographical variables. Plastic life history traits so intimately responsive to climatological variables likely contribute to N. lasiurus having one of the largest geographic ranges among Neotropical cricetids, as well as to its status as the most important plague reservoir in the Caatinga domain.
The FLAMINGO project: cosmological hydrodynamical simulations for large-scale structure and galaxy cluster surveys
Authors: Schaye Joop , Kugel Roi , Schaller Matthieu , Helly John C , Braspenning Joey , Elbers Willem , McCarthy Ian G , van Daalen Marcel P , Vandenbroucke Bert , Frenk Carlos S , Kwan Juliana , Salcido Jaime , Bahé Yannick M , Borrow Josh , Chaikin Evgenii , Hahn Oliver , Huško Filip , Jenkins Adrian , Lacey Cedric G , Nobels Folkert S J 
Published: August 2023

ABSTRACT
We introduce the Virgo Consortium’s FLAMINGO suite of hydrodynamical simulations for cosmology and galaxy cluster physics. To ensure the simulations are sufficiently realistic for studies of large-scale structure, the subgrid prescriptions for stellar and AGN feedback are calibrated to the observed low-redshift galaxy stellar mass function and cluster gas fractions. The calibration is performed using machine learning, separately for each of FLAMINGO’s three resolutions. This approach enables specification of the model by the observables to which they are calibrated. The calibration accounts for a number of potential observational biases and for random errors in the observed stellar masses. The two most demanding simulations have box sizes of 1.0 and 2.8 Gpc on a side and baryonic particle masses of 1 × 108 and $1\times 10^9\, \text{M}_\odot$, respectively. For the latter resolution, the suite includes 12 model variations in a 1 Gpc box. There are 8 variations at fixed cosmology, including shifts in the stellar mass function and/or the cluster gas fractions to which we calibrate, and two alternative implementations of AGN feedback (thermal or jets). The remaining 4 variations use the unmodified calibration data but different cosmologies, including different neutrino masses. The 2.8 Gpc simulation follows 3 × 1011 particles, making it the largest ever hydrodynamical simulation run to z = 0. Light-cone output is produced on-the-fly for up to 8 different observers. We investigate numerical convergence, show that the simulations reproduce the calibration data, and compare with a number of galaxy, cluster, and large-scale structure observations, finding very good agreement with the data for converged predictions. Finally, by comparing hydrodynamical and ‘dark-matter-only’ simulations, we confirm that baryonic effects can suppress the halo mass function and the matter power spectrum by up to ≈20 per cent.
Dwarf galaxy discoveries from the KMTNet supernova programme – III. The Milky-Way analogue NGC 2997 group
Authors: Fan Tony Junjing , Moon Dae-Sik , Park Hong Soo , Zaritsky Dennis , Kim Sang Chul , Lee Youngdae , Li Ting S , Ni Yuan Qi , Shin Jeehye , Cha Sang-Mok , Lee Yongseok 
Published: August 2023

ABSTRACT
We present the discovery of 48 new and the analysis of 55, including seven previously discovered dwarf galaxy candidates (DGCs) around the giant spiral galaxy NGC 2997 using deep BVI images from the Korea Microlensing Telescope Network Supernova Programme. Their V-band central surface brightness and total absolute magnitudes are in the range of 20.3–26.7 mag arcsec−2 and −(8.02–17.69) mag, respectively, while the I-band effective radii are 0.14–2.97 kpc. We obtain $\alpha \, \simeq$ −1.43 ± 0.02 for the faint-end slope of their luminosity function, comparable to previously measured values but shallower than theoretical predictions based on Λ cold dark matter models. The distance-independent distributions of their mass and colour suggest that the group could have recently accreted new massive members from the surrounding fields. The systematically bluer colours of the brighter members indicate younger stellar population and higher star formation activities in them, which appears to be consistent with similar findings from the SAGA or ELVES survey. We suggest that the massive and bluer dwarf galaxies in the group have experienced less environmental quenching due to their recent accretion, while environmental quenching has been more effective for the low-mass members. The interpretation of NGC 2997 being populationally young with recent accretion of massive members is also consistent with the overall morphological distribution of the dwarf galaxies showing a lack of morphologically evolved candidates but a plethora of irregularly shaped ones. Our detection rate of DGCs in the NGC 2997 group and their inferred star formation activities are comparable to those found in Milky Way analogue systems from recent surveys within the magnitude limit M$_{V}\, \lesssim$ −13 mag.
Influence of donor sex and age on graft outcome in kidney transplantation
Authors: Melk Anette , Sugianto Rizky I , Zhang Xun , Dahhou Mourad , Döhler Bernd , Süsal Caner , Sapir-Pichhadze Ruth , Wong Germaine , Foster Bethany J 
Published: August 2023

ABSTRACT

Background
There is a known recipient sex–dependent association between donor sex and kidney transplant survival. We hypothesized that donor age also modifies the association between donor sex and graft survival.

Methods
First, deceased donor kidney transplant recipients (1988–2019, n = 461 364) recorded in the Scientific Registry of Transplant Recipients, the Australia and New Zealand Dialysis and Transplant Registry and the Collaborative Transplant Study were analyzed. We used multivariable Cox regression models to estimate the association between donor sex and death censored graft loss, accounting for the modifying effects of recipient sex and donor age; donor age was categorized as 5–19, 20–34, 35–49, 50–59 and ≥60 years. Results from cohort-specific Cox models were combined using individual patient data meta-analysis.

Results
Among female recipients of donors aged &lt;60 years, graft loss hazards did not differ by donor sex; recipients of female donors ≥60 years showed significantly lower graft loss hazards than recipients of male donors of the same age [combined adjusted hazard ratio (aHR) 0.90, 95% CI 0.86–0.94]. Among male recipients, female donors aged &lt;50 years were associated with significantly higher graft loss hazards than same-aged male donors (5–19 years: aHR 1.11, 95% CI 1.02–1.21; 20–34 years: aHR 1.08, 95% CI 1.02–1.15; 35–49 years: aHR 1.07, 95% CI 1.04–1.10). There were no significant differences in graft loss by donor sex among male recipients of donors aged ≥50 years.

Conclusion
Donor age modifies the association between donor sex and graft survival. Older female donors were associated with similar or lower hazards of graft failure than older male donors in both male and female recipients, suggesting a better functional reserve of older female donor kidneys.