bluuebunny/crossref_metadata_2025_split huggingface dataset:
End-of-life interventions in patients with cancer
Authors: Webber Colleen , Hafid Shuaib , Gayowsky Anastasia , Howard Michelle , Tanuseputro Peter , Jones Aaron , Scott Mary M , Hsu Amy T , Downar James , Manuel Doug , Conen Katrin , Isenberg Sarina Roslyn 
Published: August 2023

ObjectivesTo describe variations in the receipt of potentially inappropriate interventions in the last 100 days of life of patients with cancer according to patient characteristics and cancer site.MethodsWe conducted a population-based retrospective cohort study of cancer decedents in Ontario, Canada who died between 1 January 2013 and 31 December 2018. Potentially inappropriate interventions, including chemotherapy, major surgery, intensive care unit admission, cardiopulmonary resuscitation, defibrillation, dialysis, percutaneous coronary intervention, mechanical ventilation, feeding tube placement, blood transfusion and bronchoscopy, were captured via hospital discharge records. We used Poisson regression to examine associations between interventions and decedent age, sex, rurality, income and cancer site.ResultsAmong 151 618 decedents, 81.3% received at least one intervention, and 21.4% received 3+ different interventions. Older patients (age 95–105 years vs 19–44 years, rate ratio (RR) 0.36, 95% CI 0.34 to 0.38) and women (RR 0.94, 95% CI 0.93 to 0.94) had lower intervention rates. Rural patients (RR 1.09, 95% CI 1.08 to 1.10), individuals in the highest area-level income quintile (vs lowest income quintile RR 1.02, 95% CI 1.01 to 1.04), and patients with pancreatic cancer (vs colorectal cancer RR 1.10, 95% CI 1.07 to 1.12) had higher intervention rates.ConclusionsPotentially inappropriate interventions were common in the last 100 days of life of cancer decedents. Variations in interventions may reflect differences in prognostic awareness, healthcare access, and care preferences and quality. Earlier identification of patients’ palliative care needs and involvement of palliative care specialists may help reduce the use of these interventions at the end of life.
Analysis of the geotechnical behavior of a piled raft in tropical lateritic soil based on long-term monitoring of columns, piles, and raft–soil interface
Authors: Bernardes Heitor Cardoso , da Cunha Renato Pinto , Junior Aleones José da Cruz , Sales Maurício Martines , Rebolledo Juan Félix Rodríguez 
Published: August 2023

This paper aims to analyze and describe the geotechnical behavior of a piled raft foundation of a tall building (53 floors, 172.4 m high) through the monitoring of strains in the building’s columns and piles, the stresses at the raft–soil interface, and the foundation settlements. Field and laboratory tests were performed, and associated with axisymmetric and three-dimensional finite element analysis to the assessment of the measured data. The monitoring of the pile strains suggests the occurrence of soil expansion, caused by the raft excavation process, up to approximately 6 months after the excavation was completed. The presence of different soil profiles under the raft, with different mechanical properties, affected the distribution of the foundation settlements and the pile loads. Initially, the average pile loads were concentrated in the perimeter elements, but, as the construction of the building evolved, they tended to become more uniform. The effect of the superstructure stiffness caused successive load redistributions in the columns, which contributed to the maintenance of the maximum angular distortion of the building within the allowable values and reduced the load difference between the piles positioned in opposite soil profiles.
TALYS calculations of prompt fission observables and independent fission product yields for the neutron-induced fission of $$^{235}$$U
Authors: Fujio Kazuki , Al-Adili Ali , Nordström Fredrik , Lemaître Jean-François , Okumura Shin , Chiba Satoshi , Koning Arjan 
Published: August 2023

AbstractThe TALYS nuclear reaction code’s Hauser-Feshbach statistical decay model has been adapted in order to calculate prompt fission neutron and$$\gamma $$γ-ray observables by iterating over deexciting fission fragments. Several fission fragment generators such as GEF, HF$$^{3}$$3D, and SPY were employed to provide TALYS with databases. These databases contain standardized tables with fission fragment yields, mean excitation energies and their widths, and average total kinetic energy, as a function of charge and mass number of primary fission fragments. The resulting calculations, including prompt particle multiplicities, spectra, average energies, and independent fission product yields, were compared with experimental and evaluated data. This work first outlines the new methodology implemented in TALYS and examines the effects of three important parameters on the final evaporation data. Furthermore, the neutron-induced fission of$$^{235}$$235U is investigated in detail as a function of incident energy. The results from TALYS, with input from GEF and HF$$^{3}$$3D, were compared with available experimental data and the results of the stand-alone GEF code. The proposed methodology contributes to an improved capability to model the fission process.
No-signaling-in-time as a condition for macrorealism: the case of neutrino oscillations
Authors: Blasone Massimo , Illuminati Fabrizio , Petruzziello Luciano , Simonov Kyrylo , Smaldone Luca 
Published: August 2023

AbstractWe consider two necessary and sufficient conditions for macrorealism recently appeared in the literature, known as no-signaling-in-time and arrow-of-time conditions, respectively, and study them in the context of neutrino flavor transitions, within both the plane wave description and the wave packet approach. We then compare the outcome of the above investigation with the implication of various formulations of Leggett–Garg inequalities. In particular, we show that the fulfillment of the addressed conditions for macrorealism in neutrino oscillations implies the fulfillment of the Leggett–Garg inequalities, whereas the converse is not true. Finally, in the framework of wave packet approach, we also prove that, for distances longer than the coherence length, the no-signaling-in-time condition is always violated whilst the Leggett–Garg inequalities are not.
Super-swelling behavior of stacked lipid bilayer systems
Authors: Rueben Jacob , Steer Dylan , Leal Cecília 
Published: August 2023

Abstract
Bilayer systems comprising lipid mixtures are the most well-studied model of biological membranes. While the plasma membrane of the cell is a single bilayer, many intra- and extra-cellular biomembranes comprise stacks of bilayers. Most bilayer stacks in nature are periodic, maintaining a precise water layer separation between bilayers. That equilibrium water separation is governed by multiple inter-bilayer forces and is highly responsive. Biomembranes re-configure inter-bilayer spacing in response to temperature, composition, or mass transport cues. In synthetic bilayer systems for applications in cosmetics or topical treatments, control of the hydration level is a critical design handle. Herein we investigate a binary lipid system that leverages key inter-bilayer forces leading to unprecedented levels of aqueous swelling while maintaining a coherent multilamellar form. We found that combining cationic lipids with bicontinuous cubic phase-forming lipids (lipids with positive Gaussian modulus), results in the stabilization of multilamellar phases against repulsive steric forces that typically lead to bilayer delamination at high degrees of swelling. Using ultra-small-angle X-ray scattering alongside confocal laser scanning microscopy, we characterized various super-swelled states of 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP) and glycerol monooleate (GMO) lipids, as well as other analogous systems, at varied concentration and molar ratios. Through these experiments we established swelling profiles of various binary lipid systems that were near-linear with decreasing lipid volume fraction, showing maximum swelling with periodicity well above 200 nanometers.

Graphical abstract
Confocal fluorescence micrograph of super-swelled multilamellar structures in 90GMOD sample at 25 mM concentration. Inset plot shows intensity profile of orange line, with pink triangles indicating maxima.
Rare earth-doped glass whispering gallery mode micro-lasers
Authors: Frigenti Gabriele , Berneschi Simone , Farnesi Daniele , Pelli Stefano , Righini Giancarlo C. , Soria Silvia , Dumeige Yannick , Féron Patrice , Ristić Davor , Prudenzano Francesco , Ferrari Maurizio , Nunzi Conti Gualtiero 
Published: August 2023

AbstractWe review the works performed on whispering gallery mode (WGM) micro-optical resonators made in rare-earth (RE) doped glasses for implementing low threshold and narrow line coherent sources. These types of micro-lasers, because of their small size and ease of fabrication can be a useful tool for the characterization of laser glasses and have several applications, especially as sensors.
EM wave propagation within plasma-filled rectangular waveguide using fractional space and LFD
Authors: Refaie Ali A. , Eldabe N. T. M. , El Naby A. E. H. Abd , Ibrahim M. , Abo-Seida O. M. 
Published: August 2023

AbstractThis paper aims to investigate the propagation of the electromagnetic (EM) within the rectangular waveguide that is filled with plasma. A rapid Cherenkov free electron laser ( C-FEL) beam was injected into the plasma to excite its natural oscillations and, therefore, an EM wave was generated. We focused on TM-mode propagation through this waveguide. Exact solutions of the EM wave equation have been found using both the Laplacian operator in the fractional D-dimensional space and the local fractional derivative (LFD). The fractional solutions have been converted into classical results to simulate the usual behavior of the waves. It has been found that the well-known Bessel, Neumann, and Mittage–Leffler functions are observed and their propagation is directly proportional to fractional parameters.
Route optimization via improved ant colony algorithm with graph network
Authors: N. Siddalingappa Patil , Basavaraj Poornima , Basavaraj Preethi , B. Gowramma Premasudha 
Published: August 2023

<p>Route optimization problem using vehicle routing problem (VRP) and time window constraint is explained as finding paths for a finite count of vehicles to provide service to a huge number of customers and hence, optimizing the path in a given duration of the time window. The vehicles in the loop have restricted intake of capacity. This path initiates from the depot, delivers the goods, and stops at the depot. Each customer is to serve exactly once. If the arrival of the vehicle is before the time window “opens” or when the time window “closes,” there will be waiting for cost and late cost. The challenge involved over here is to scheduling visits to customers who are only available during specific time windows. Ant colony optimization (ACO) algorithm is a meta-heuristic algorithm stimulated by the growing behaviour of real ants. In this paper, we combine the ACO algorithm with graph network henceforth increasing the number of vehicles in a particular depot for increasing the efficiency for timely delivery of the goods in a particular time width. This problem is solved by, an efficient technique known as the ACO+graph algorithm.</p>
FURTHER STUDY ON TWO SPECIES OF LOACH FISHES (Cypriniformes: Nemacheilidae: Nemacheilus) BASED ON MORPHOLOGY AND MOLECULAR DATA
Authors: Rahayu Dwi 
Published: August 2023

The identity of two local loaches, Nemacheilus chrysolaimos (Valenciennes, 1846) and N. fasciatus (Valenciennes, 1846), is revealed in this study using morphology and molecular approach based on our collection from six rivers at Biltar, East Java Indonesia. Based on morphology, these two species can be distinguished mainly from the dark bars or dark spots on the lateral body. The meristic data for N. chrysolaimos in this study is DII. 7–8 (dorsal fin), AI. 3–5 (anal fin), PI. 9 (pectoral fin), VI. 6–7 (ventral fin) and C. 17 (caudal fin), meanwhile, for N. fasciatus with D II 7–8 (dorsal fin), AI. 6 (anal fin), PI. 9–10 (pectoral fin), VI. 6–7 (ventral fin) and C. 17 (audal fin). There was a significant difference on the morphometric of N. fasciatus form sampling sites using Kruskal-Wallis Test. The nucleotide base composition sequences consisted of the mean of Thiamine (T) 29.565%, Cytosine (C) 32.023%, Adenine (A) 23.88%, and Guanine (G) 16.244%. Maximum Likelihood (ML) and Neighbour Joining (NJ) analysis was conducted using the Kimura 2 Parameter model to establish two major clades on Nemacheilus spp. and one out-groups clades significantly different from the Nemacheilus spp. These major clades were closely related to each other at the 100% evidence of bootstrap, which grouped as genus Nemacheilus. The present study on Nemacheilus spp. from the Blitar locality was able to differentiate COI sequences between N. fasciatus and N. chrysolaimos. Moreover, N. crysolaimos from references sequence was inferred as the ancestor to N crysolaimos MZB 26540 and MZB 26539. ABGD analyses at a prior maximal distance of 0.025 also delineated this species into a separate partition.
Effect of short-term growth of mung bean and its incorporation with nitrogen fertiliser on the density of the root-knot nematode, Meloidogyne incognita, in soil
Authors: Zeng Yayun , Perry Roland N. , Toyota Koki 
Published: August 2023

Summary
Soybean is attacked by multiple plant-parasitic nematodes and the major ones are soybean cyst nematode (SCN) and root-knot nematodes. Our previous study reported that 2 weeks growth of mung bean and its soil incorporation markedly reduced SCN density in soil via hatching stimulation by mung bean residue. This study aimed: i) to evaluate whether incorporation of mung bean in combination with N fertiliser decreased the density of Meloidogyne incognita, which attacks both soybean and mung bean; and ii) to determine the direct effect of ammonium solutions on M. incognita J2 and hatching. The results showed that after the growth period of mung bean for 2 weeks and 4 weeks of its incorporation, the density of M. incognita was significantly reduced by 54 and 72% in the mung bean treatment with and without N fertiliser (140 mg N (kg soil)−1), respectively, compared with the control. Soil urease activity was significantly higher in the mung bean with N fertiliser than in the control. Meloidogyne incognita second-stage juveniles were less mobile in NH4Cl solutions with 100-250 mg N l−1 than in 0 mg N l−1. Moreover, NH4Cl solutions with 140 mg N l−1 and 250 mg N l−1 significantly inhibited the hatching of M. incognita. This study demonstrated that 2 weeks growth of mung bean may be a potential trap crop for M. incognita and N metabolism might be involved to a certain extent in the suppression of M. incognita.
Seasonal Dependence of the Pacific–North American Teleconnection Associated with ENSO and Its Interaction with the Annual Cycle
Authors: Hu Suqiong , Zhang Wenjun , Jin Fei-Fei , Hong Li-Ciao , Jiang Feng , Stuecker Malte F. 
Published: August 2023

Abstract
The Pacific–North American (PNA) teleconnection pattern is one of the prominent atmospheric circulation modes in the extratropical Northern Hemisphere, and its seasonal to interannual predictability is suggested to originate from El Niño–Southern Oscillation (ENSO). Intriguingly, the PNA teleconnection pattern exhibits variance at near-annual frequencies, which is related to a rapid phase reversal of the PNA pattern during ENSO years, whereas the ENSO sea surface temperature (SST) anomalies in the tropical Pacific are evolving much slower in time. This distinct seasonal feature of the PNA pattern can be explained by an amplitude modulation of the interannual ENSO signal by the annual cycle (i.e., the ENSO combination mode). The ENSO-related seasonal phase transition of the PNA pattern is reproduced well in an atmospheric general circulation model when both the background SST annual cycle and ENSO SST anomalies are prescribed. In contrast, this characteristic seasonal evolution of the PNA pattern is absent when the tropical Pacific background SST annual cycle is not considered in the modeling experiments. The background SST annual cycle in the tropical Pacific modulates the ENSO-associated tropical Pacific convection response, leading to a rapid enhancement of convection anomalies in winter. The enhanced convection results in a fast establishment of the large-scale PNA teleconnection during ENSO years. The dynamics of this ENSO–annual cycle interaction fills an important gap in our understanding of the seasonally modulated PNA teleconnection pattern during ENSO years.
The Influence of Equatorial Cooling on Axially Symmetric Atmospheric Circulation Forced by Annually Averaged Heating
Authors: Adam Ori 
Published: August 2023

Abstract
Axisymmetric theory of atmospheric circulation is extended for the case of concentrated equatorial cooling and annually averaged heating. The solutions are derived in a 1.5-layer shallow water model on the spherical Earth, which includes vertical mixing with diagnostic surface momentum. The axisymmetric solutions capture the sensitivity of the large-scale circulation to equatorial cooling seen in observations and in eddy-permitting models, namely, (i) weakening and widening of the meridional overturning circulation (MOC) and (ii) weakening and poleward shift of the subtropical jet. For sufficiently large equatorial cooling, a tropical anti-Hadley cell emerges that transports energy equatorward, balancing the equatorial energetic sink. The analytic solutions predict the critical cooling required for the emergence of the anti-Hadley cell and provide a simple mechanism for the response of the MOC to equatorial cooling. Specifically, equatorial cooling reduces net tropical heating, which weakens the circulation and shifts the edge of the rising branch poleward. This in turn reduces upper-level momentum which is set by surface momentum in the rising branch. The subtropical meridional temperature gradient decreases with upper-level momentum, requiring a widening of the circulation to close the energy budget. The subtropical jet therefore shifts poleward with the edge of the MOC and weakens due to the reduced upper-level angular momentum. The strong sensitivity to equatorial cooling seen in the axisymmetric system suggests that the above mechanism may have an important role in the sensitivity of the MOC to equatorial temperature anomalies on seasonal or longer time scales.

Significance Statement
Axisymmetric solutions for the response of the atmospheric circulation to concentrated equatorial cooling are derived, motivated by the equatorial cooling by the cold tongues of the Pacific and Atlantic. The solutions capture the response of the large-scale realistic atmosphere to equatorial cooling, namely a weakening and widening of the meridional overturning circulation and a weakening and poleward shift of the subtropical jet. In addition, for sufficiently strong cooling, a tropical anti-Hadley cell emerges. The solutions provide insight into the influence of biases in the representation of the cold tongues in climate models, the relation of interannual equatorial variability to the large-scale circulation, and changes in the large-scale atmospheric circulation on geological time scales.
Effects of Silent Intervals on the Extraction of Human Frequency-Following Responses Using Non-Negative Matrix Factorization
Authors: Giordano Allison T. , Jeng Fuh-Cherng , Black Taylor R. , Bauer Sydney W. , Carriero Amanda E. , McDonald Kalyn , Lin Tzu-Hao , Wang Ching-Yuan 
Published: August 2023

Source-Separation Non-Negative Matrix Factorization (SSNMF) is a mathematical algorithm recently developed to extract scalp-recorded frequency-following responses (FFRs) from noise. Despite its initial success, the effects of silent intervals on algorithm performance remain undetermined. Our purpose in this study was to determine the effects of silent intervals on the extraction of FFRs, which are electrophysiological responses that are commonly used to evaluate auditory processing and neuroplasticity in the human brain. We used an English vowel /i/ with a rising frequency contour to evoke FFRs in 23 normal-hearing adults. The stimulus had a duration of 150 ms, while the silent interval between the onset of one stimulus and the offset of the next one was also 150 ms. We computed FFR Enhancement and Noise Residue to estimate algorithm performance, while silent intervals were either included (i.e., the WithSI condition) or excluded (i.e., the WithoutSI condition) in our analysis. The FFR Enhancements and Noise Residues obtained in the WithoutSI condition were significantly better ( p < .05) than those obtained in the WithSI condition. On average, the exclusion of silent intervals produced a 11.78% increment in FFR Enhancement and a 20.69% decrement in Noise Residue. These results not only quantify the effects of silent intervals on the extraction of human FFRs, but also provide recommendations for designing and improving the SSNMF algorithm in future research.
Enhanced effect of chloroprene on the mechanical properties of polyurethane foams
Authors: Hosseinpour Masoumeh , Ashjari Hamid Reza , Seyed Dorraji Mir Saeed , Rastgouy-Houjaghan Mehrdad , Faraji Sheida 
Published: August 2023

In this research, a new method to increase the mechanical properties of the low-density polyurethane foams (PUFS) has been described. Chloroprene rubber (CR) is used as reinforcing the mechanical properties of the foam. Polyurethane foam (PUF) containing CR (PUF/CR) and pure PUF were characterized by mechanical testing, Fourier transform infrared spectroscopy (FT-IR), Scanning electron microscopy (SEM), Differential scanning calorimeter (DSC), Thermogravimetric analysis (TGA). The results of mechanical properties show the tensile strength of PUFS containing 0, 1, 2, 3, 4 and 5 wt% CR are 38.2, 42, 56.4, 61.48, 77.3 and 77.18 kPa, respectively. Also the morphological studies show by increasing the amount of CR in the foam structure, the foam cells are smaller and more closed.
Effect of peri-operative intra-aortic balloon pump in patients undergoing coronary artery bypass grafting on outcomes in a resource limited setting
Authors: Sohail Abdul Ahad , Samejo Areeba , Bajwa Hamza , Wahab Rida , Asif Narmeen , Inam Hina , Shahabuddin Syed 
Published: August 2023

Introduction Intra-aortic balloon pump (IABP) insertion for diminished myocardial function is standard of care in cardiac surgery. Previous studies have suggested a possible benefit to IABP support before surgery with regards to outcomes and complications. However, there are conflicts with other studies suggesting no significant benefit. Optimal time of insertion, whether preoperative or perioperative (intra-operative and post-operative), has yet to be defined. Methodology A retrospective, hospital records-based chart review was conducted for patients admitted to our center from January 2015 to December 2019 for coronary bypass surgery necessitating IABP insertion. Cases were stratified according to the timing of insertion and analyzed according to surgical outcomes and complication rates. Results Out of 97 patients, 84.5% underwent preoperative IABP insertion while 15.5% of patients received perioperative (Intra-operative or post-operative) insertion. In-hospital mortality was significantly higher in patients with perioperative IABP insertion as compared to the preoperative group (60% vs 20.7%, p = 0.003). However, there were no significant differences between 30-day readmission rates in the two groups (9.8% vs 6.7%, p = 1.000). Length of stay was also higher in patients with preoperative insertion of IABP ( p = 0.032), with no significant difference in ICU stay ( p = 0.107). Perioperative IABP patients had higher rates of arrhythmias (46.7%, p = 0.042) and reopening of patient (33.3%, p = 0.028). Conclusion Our study shows improved mortality in patients with preoperatively inserted IABP. This may be beneficial for high-risk patients undergoing CABG surgery. Expanding the use of IABP before CABG in third world countries such as Pakistan may improve overall survival for patients.