bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fast Expandable Chitosan‐Fibers Cryogel from Ambient Drying for Noncompressible Bleeding Control and In Situ Tissue Regeneration
Authors: Qi Luhe , Mu Lanxin , Guo Xiaojia , Liu Anxiong , Chen Chaoji , Ye Qifa , Zhong Zibiao , Shi Xiaowen 
Published: March 2023

AbstractHemorrhage control, especially noncompressible wound hemostasis, is a tremendous challenge in military injuries and other traumas worldwide. Here, a cryogelation strategy and subsequent solvent exchange are developed for the hydrogen bond‐induced self‐assembly of chitosan fibers and the production of fast expandable chitosan cryogel. Importantly, the ambient drying process facilitates the repeatable deformation performance of the shape‐memory cryogel with a response time of ≈1.7 s. Due to the capillary‐like structure of the cryogel and high hydrophilicity, rapid shape recovery is accompanied by 41 times water absorption ability. It is further demonstrated that chitosan cryogel is beneficial for in situ tissue regeneration by taking advantage of the biodegradability and biocompatibility of chitosan. Thus, chitosan cryogels prepared by this simple and benign method should have efficient hemostatic effect on noncompressible bleeding and severe fatal high‐pressure hemorrhage.
Mitochondrial Calcium Ion Nanogluttons Alleviate Periodontitis via Controlling mPTPs
Authors: He Ping , Liu Fengyi , Li Mingzheng , Ren Mingxing , Wang Xu , Deng Yangjia , Wu Xianghao , Li Yuzhou , Yang Sheng , Song Jinlin 
Published: March 2023

AbstractThe mitochondrial permeability transition (mPT) directly affects mitochondrial function in macrophages. Under inflammatory conditions, mitochondrial calcium ion (mitoCa2+) overload triggers the persistent opening of mPT pores (mPTPs), further aggravating Ca2+ overload and increasing reactive oxygen species (ROS) to form an adverse cycle. However, there are currently no effective drugs targeting mPTPs to confine or unload excess Ca2+. It is novelly demonstrated that the initiation of periodontitis and the activation of proinflammatory macrophages depend on the persistent overopening of mPTPs, which is mainly triggered by mitoCa2+ overload and facilitates further mitochondrial ROS leakage into the cytoplasm. To solve the above problems, mitochondrial‐targeted “nanogluttons” with PEG‐TPP conjugated to the surface of PAMAM and BAPTA‐AM encapsulated in the core are designed. These nanogluttons can efficiently “glut” Ca2+ around and inside mitochondria to effectively control the sustained opening of mPTPs. As a result, the nanogluttons significantly inhibit the inflammatory activation of macrophages. Further studies also unexpectedly reveal that the alleviation of local periodontal inflammation in mice is accompanied by diminished osteoclast activity and reduced bone loss. This provides a promising strategy for mitochondria‐targeted intervention in inflammatory bone loss in periodontitis and can be extended to treat other chronic inflammatory diseases associated with mitoCa2+ overload.
Two‐Dimensional Cs2AgInxBi1‐xCl6 Alloyed Double Perovskite Nanoplatelets for Solution‐Processed Light‐Emitting Diodes
Authors: Liu Zhenyang , Sun Yingying , Cai Tong , Yang Hanjun , Zhao JinXing , Yin Tao , Hao Chaoqi , Chen Mingjun , Shi Wenwu , Li Xiaoxiao , Guan Li , Li Xu , Wang Xinzhong , Tang Aiwei , Chen Ou 
Published: March 2023

AbstractLead‐free double perovskites have emerged as a promising class of materials with potential to be integrated into a wide range of optical and optoelectronic applications. Herein, the first synthesis of 2D Cs2AgInxBi1‐xCl6 (0 ≤ x ≤ 1) alloyed double perovskite nanoplatelets (NPLs) with well controlled morphology and composition is demonstrated. The obtained NPLs show unique optical properties with the highest photoluminescence quantum yield of 40.1%. Both temperature dependent spectroscopic studies and density functional theory calculation results reveal that the morphological dimension reduction and In–Bi alloying effect together boost the radiative pathway of the self‐trapped excitons of the alloyed double perovskite NPLs. Moreover, the NPLs exhibit good stability under ambient conditions and against polar solvents, which is ideal for all solution‐processing of the materials in low‐cost device manufacturing. The first solution‐processed light‐emitting diodes is demonstrated using the Cs2AgIn0.9Bi0.1Cl6 alloyed double perovskite NPLs as the sole emitting component, showing luminance maximum of 58 cd m−2 and peak current efficiency of 0.013 cd A−1. This study sheds light on morphological control and composition‐property relationships of double perovskite nanocrystals, paving the way toward ultimate utilizations of lead‐free perovskite materials in diverse sets of real‐life applications.
Perovskite‐Solar‐Cell‐Powered Integrated Fuel Conversion and Energy‐Storage Devices
Authors: Yang Gege , Yang Wenhan , Gu Hao , Fu Ying , Wang Bin , Cai Hairui , Xia Junmin , Zhang Nan , Liang Chao , Xing Guichuan , Yang Shengchun , Chen Yiwang , Huang Wei 
Published: March 2023

AbstractMetal halide hybrid perovskite solar cells (PSCs) have received considerable attention over the past decade owing to their potential for low‐cost, solution‐processable, earth‐abundant, and high‐performance superiority, increasing power conversion efficiencies of up to 25.7%. Solar energy conversion into electricity is highly efficient and sustainable, but direct utilization, storage, and poor energy diversity are difficult to achieve, resulting in a potential waste of resources. Considering its convenience and feasibility, converting solar energy into chemical fuels is regarded as a promising pathway for boosting energy diversity and expanding its utilization. In addition, the energy conversion–storage integrated system can efficiently sequentially capture, convert, and store energy in electrochemical energy storage devices. However, a comprehensive overview focusing on PSC‐self‐driven integrated devices with a discussion of their development and limitations remains lacking. Here, focus is on the development of representative configurations of emerging PSC‐based photo‐electrochemical devices including self‐charging power packs, unassisted solar water splitting/CO2 reduction. The advanced progresses in this field, including configuration design, key parameters, working principles, integration strategies, electrode materials, and their performance evaluations are also summarized. Finally, scientific challenges and future perspectives for ongoing research in this field are presented.
Rising of Dynamic Polyimide Materials: A Versatile Dielectric for Electrical and Electronic Applications
Authors: Wan Baoquan , Dong Xiaodi , Yang Xing , Wang Jiangqiong , Zheng Ming‐Sheng , Dang Zhi‐Min , Chen George , Zha Jun‐Wei 
Published: March 2023

AbstractPolyimides (PIs) are widely used in circuit components, electrical insulators, and power systems in modern electronic devices and large electrical appliances. Electrical/mechanical damage of materials are important factors that threaten reliability and service lifetime. Dynamic (self‐healable, recyclable and degradable) PIs, a promising class of materials that successfully improve electrical/mechanical properties after damage, are anticipated to solve this issue. The viewpoints and perspectives on the status and future trends of dynamic PI based on a few existing documents are shared. The main damage forms of PI dielectric materials in the application process are first introduced, and initial strategies and schemes to solve these problems are proposed. Fundamentally, the bottleneck issues faced by the development of dynamic PIs are indicated, and the relationship between various damage forms and the universality of the method is evaluated. The potential mechanism of the dynamic PI to deal with electrical damage is highlighted and several feasible prospective schemes to address electrical damage are discussed. This study is concluded by presenting a short outlook and future improvements to systems, challenges, and solutions of dynamic PI in electrical insulation. The summary of theory and practice should encourage policy development favoring energy conservation and environmental protection and promoting sustainability.
Control of Droplet Impact through Magnetic Actuation of Surface Microstructures
Authors: Jezeršek Matija , Kriegl Raphael , Kravanja Gaia , Hribar Luka , Drevenšek‐Olenik Irena , Unold Heiko , Shamonin Mikhail 
Published: March 2023

AbstractAn effective method for on‐demand control over the impact dynamics of droplets on a magnetoresponsive surface is reported. The surface is comprised of micrometer‐sized lamellas from a magnetoactive elastomer on a copper substrate. The surface itself is fabricated using laser micromachining. The orientation of the lamellae is switched from edge‐on (orthogonal to the surface) to face‐on (parallel to the surface) by changing the direction of a moderate (<250 mT) magnetic field. This simple actuation technique can significantly change the critical velocities of droplet rebound, deposition, and splashing. Rebound and deposition regimes can be switched up to Weber number We < 13 ± 3, while deposition and splashing can be switched in the range of 32 < We < 52. Because a permanent magnet is used, no permanent power supply is required for maintaining the particular regime of droplet impact. The presented technology is highly flexible and enables selective fabrication and actuation of microstructures on complex devices. It has great potential for applications in soft robotics, microfluidics, and advanced thermal management.
Linking Phase Behavior to Performance Parameters in Non‐Fullerene Acceptor Solar Cells
Authors: Cheng Christina , Wong Stephen , LeCroy Garrett , Schneider Sebastian , Gomez Enrique , Toney Michael F. , Salleo Alberto 
Published: March 2023

AbstractPerformance of nonfullerene‐based organic solar cells is largely dependent on the donor:acceptor blend morphology, which is initially tuned by composition. However, morphological design rules are difficult to identify due to the complex relationship between composition‐dependent phase behavior and performance properties. In this study, the authors are able to establish a direct link between PM6:Y6 film morphology and device properties by combining grazing‐incidence wide‐angle X‐ray scattering with highly sensitive Fourier transform photocurrent spectroscopy. By analyzing properties across the full composition range, interfacial microstructure and the corresponding charge transfer (CT) states are identified and direct structure–property relationships are established. The results indicate that open‐circuit voltage is controlled by the CT state at amorphous‐PM6:crystalline‐Y6 interfaces. Crystalline Y6 is found to increase both transport and non‐radiative recombination, suggesting that morphological tradeoffs may be necessary for overall device optimization.
Polygenic prediction of bipolar disorder in a Latin American sample
Authors: Cuellar‐Barboza Alfredo B. , Prieto Miguel L. , Coombes Brandon J. , Gardea‐Resendez Manuel , Núñez Nicolás , Winham Stacey J. , Romo‐Nava Francisco , González Sarai , McElroy Susan L. , Frye Mark A. , Biernacka Joanna M. 
Published: March 2023

AbstractTo date, bipolar disorder (BD) genetic studies and polygenic risk scores (PRSs) for BD are based primarily on populations of European descent (EUR) and lack representation from other ancestries including Latin American (LAT). Here, we describe a new LAT cohort from the Mayo Clinic Bipolar Biobank (MCBB), a multisite collaboration with recruitment sites in the United States (EUR; 1,443 cases and 777 controls) and Mexico and Chile (LAT; 211 cases and 161 controls) and use the sample to explore the performance of a BD‐PRS in a LAT population. Using results from the largest genome‐wide association study of BD in EUR individuals, PRSice2 and LDpred2 were used to compute BD‐PRSs in the LAT and EUR samples from the MCBB. PRSs explained up to 1.4% (PRSice) and 4% (LDpred2) of the phenotypic variance on the liability scale in the LAT sample compared to 3.8% (PRSice2) and 3.4% (LDpred2) in the EUR samples. Future larger studies should further explore the differential performance of different PRS approaches across ancestries. International multisite studies, such as this one, have the potential to address diversity‐related limitations of prior genomic studies and ultimately contribute to the reduction of health disparities.
Ancient mitogenomes from the Southern Pampas of Argentina reflect local differentiation and limited extra‐regional linkages after rapid initial colonization
Authors: Motti Josefina M. B. , Pauro Maia , Scabuzzo Clara , García Angelina , Aldazábal Verónica , Vecchi Rodrigo , Bayón Cristina , Pastor Nicolás , Demarchi Darío A. , Bravi Claudio M. , Reich David , Cabana Graciela S. , Nores Rodrigo 
Published: March 2023

AbstractObjectiveThis study aims to contribute to the recovery of Indigenous evolutionary history in the Southern Pampas region of Argentina through an analysis of ancient complete mitochondrial genomes.Materials and MethodsWe generated DNA data for nine complete mitogenomes from the Southern Pampas, dated to between 2531 and 723 cal BP. In combination with previously published ancient mitogenomes from the region and from throughout South America, we documented instances of extra‐regional lineage‐sharing, and estimated coalescent ages for local lineages using a Bayesian method with tip calibrations in a phylogenetic analysis.ResultsWe identified a novel mitochondrial haplogroup, B2b16, and two recently defined haplogroups, A2ay and B2ak1, as well as three local haplotypes within founder haplogroups C1b and C1d. We detected lineage‐sharing with ancient and contemporary individuals from Central Argentina, but not with ancient or contemporary samples from North Patagonian or Littoral regions of Argentina, despite archeological evidence of cultural interactions with the latter regions. The estimated coalescent age of these shared lineages is ~10,000 years BP.DiscussionThe history of the human populations in the Southern Pampas is temporally deep, exhibiting long‐term continuity of mitogenome lineages. Additionally, the identification of highly localized mtDNA clades accords with a model of relatively rapid initial colonization of South America by Indigenous communities, followed by more local patterns of limited gene flow and genetic drift in various South American regions, including the Pampas.
Differing unsaturation levels of soybean oils impact the properties of peroxide‐vulcanized carbon black‐filled ethylene‐propylene‐diene monomer rubber
Authors: Shafranska Olena , Dahlgren Joseph , Jones Alexander , Tardiff Janice , Webster Dean C. 
Published: March 2023

AbstractSoybean oils having less unsaturation than conventional soybean oil (SBO) were studied as sustainable plasticizers for ethylene‐propylene‐diene monomer (EPDM) rubber compounds vulcanized with peroxide. In EPDM formulations, part of the petroleum‐based paraffinic oil (PO) was replaced with soy‐derived plasticizers such as high oleic soybean oil (HOSO), partially hydrogenated soybean oil (PHSO), and completely hydrogenated soybean oil (HSO). The mechanical and viscoelastic properties of EPDM rubbers formulated with soy‐derived plasticizers were studied and compared with the properties of PO‐based rubber. Torque rheometry was used to study the vulcanization process and the properties of the vulcanized rubber compounds were evaluated using tensile testing, compression testing, dynamic mechanical analysis, and solvent swelling experiments. The equilibrium swelling test and examination of gel fraction demonstrated the incorporation of soy‐based process aids into the rubber network during vulcanization. It was found that soy‐derived plasticizers could partially substitute for the petroleum‐based plasticizer in EPDM compounds with minimal impact on properties. An additional benefit of the use of hydrogenated SBO is the increase of crosslink density in vulcanized rubber indicating enhanced peroxide efficiency.
Toward Highly Reliable Potassium‐Ion Half and Full Coin Cells
Authors: Larhrib Badre , Madec Lénaïc 
Published: March 2023

AbstractTo develop high energy and high‐power potassium‐ion batteries (KIBs), performance need to be evaluated in full‐cells instead of half‐cells based on the highly reactive K metal that leads to misinterpretation of the results. However, assembling KIBs full‐cells is not trivial as many parameters are critical to the obtained performance. This work demonstrates approaches to assemble reliable K‐ion full‐cells using graphite and KVPO4F0.5O0.5 based electrodes. First, the optimal separators choice/number and electrolyte choice/volume are determined in half‐cells then the optimal electrolyte volume is determined in full‐cells. Importantly, the electrolyte volume should be fixed to about 4 times the porosity volume for both half‐ and full‐cells. Then, using 3‐electrodes cells, the optimal negative/positive (N/P) diameter ratio then the optimal N/P capacity ratio are determined to be 1.16±0.2. Finally, these approaches allow assembling KVPFO//graphite coin‐cells with an energy density of about 47 Wh kgdevice−1 using a high N/P loading ratio of 4/10 (in mgactive‐material cm−2). Overall, this work can be used as a guide to assemble any KIBs full‐cell system and thus paves the way to the determine the best negative/positive materials combination in order to develop efficient KIBs.
Piperacillin/Tazobactam in critically ill morbidly obese patients: A case series: The first One‐Centre experience with TDM
Authors: Mieresova M. , Balazova K. , Kubele J. , Cerny D. , Halacova M. 
Published: March 2023

AbstractThe aim of this article is to demonstrate extreme interindividual variability of piperacilin/tazobactam (PIP/TAZO) pharmacokinetics in critically ill morbidly obese patients and to emphasize the need for the practice of routine PIP/TAZO plasma concentrations measurement in order to ensure optimal efficacy and safety of antibiotic therapy.
Practical Aspects of Thermal Dissociation and Recombination Reactions: The Reaction Systems CF3X(+M)↔CF3+X (+M) with X=F, Cl, Br, and I
Authors: Cobos Carlos Jorge , Tellbach Elsa , Sölter Lars , Troe Jürgen 
Published: March 2023

AbstractThe thermal dissociation/recombination reactions of the perfluoromethyl halides CF4↔CF3+F, CF3Cl↔CF3+Cl, CF3Br↔CF3+Br, and CF3I↔CF3+I are analyzed with respect to their transition (for increasing pressures) from second‐order to first‐order dissociation (or from third‐order to second‐order recombination). The dependence of this transition on the temperature is documented. Practical aspects of the modelling of falloff curves are discussed.
The Mobility of Homomeric Lasso‐ and Daisy Chain‐Like Rotaxanes in Solution and in the Gas Phase as a Means to Study Structure and Switching Behaviour
Authors: Saura‐Sanmartin Adrian , Schalley Christoph A. 
Published: March 2023

AbstractA precise structural determination of supramolecular architectures is a non‐trivial challenge. This daunting task can be made even more difficult when interlocked species are to be analysed having macrocycles covalently equipped with a thread as repeating units, such as molecular lassos and daisy chains. When such functionalized macrocycles are included as scaffolds, different products having analogous NMR spectra as well as dynamic libraries can be obtained. Furthermore, if control over the motion of the parts relative to each other is to be achieved, a full understanding of the machinery's operation mechanism requires detailed insight into the structures involved. This understanding also helps designing improved synthetic molecular machines. Diffusion‐ordered NMR spectroscopy and ion‐mobility MS techniques are ideal tools to study such compounds in depth. This review covers recent examples on the use of the above‐mentioned techniques to characterize these interlocked architectures.
Classification method based on Siamese‐like neural network for inter‐species blood Raman spectra similarity measure
Authors: Tian Xianli , Wang Peng , Tian Yubing , Zhang Rui , Jiang Zhehan , Gao Jing 
Published: March 2023

AbstractAnalysis of blood species is an extremely important part in customs inspection, forensic investigation, wildlife protection and other fields. In this study, a classification method based on Siamese‐like neural network (SNN) for interspecies blood (22 species) was proposed to measure Raman Spectra similarity. The average accuracy was above 99.20% in the test set of spectra (known species) that did not appear in the training set. This model could detect species not represented in the dataset underlying the model. After adding new species to the training set, we can update the training based on the original model without retraining the model from scratch. For species with lower accuracy, SNN model can be trained intensively in the form of enriched training data for that species. A single model can achieve both multiple‐classification and binary classification functions. Moreover, SNN showed higher accuracy rates when trained with smaller datasets compared to other methods.
Intraseasonal descriptors and extremes in South African rainfall. Part II: Summer teleconnections across multiple timescales
Authors: Ullah Asmat , Pohl Benjamin , Pergaud Julien , Dieppois Bastien , Rouault Mathieu 
Published: March 2023

AbstractExtreme events contribute significantly to rainfall variability in semi‐arid regions like South Africa. Here, following the definition of a novel typology of rainfall extremes, disentangling large‐ and small‐scale events in Part I, we use quality‐controlled observational databases in South Africa, the ERA5 reanalysis and satellite estimates TRMM‐3B42 to examine the relationship between these two types of rainfall extremes and different modes of climate variability at various timescales. At low frequencies, rainfall extremes are assessed at interannual (IV: 2–8 years) and quasi‐decadal (QDV: 8–13 years) timescales, which are primarily associated with the El Niño–Southern Oscillation (ENSO) and the Interdecadal Pacific Oscillation (IPO), respectively. At subseasonal timescales, the typology of rainfall extremes is analysed depending on the synoptic configurations, as inferred by seven convective regimes including tropical temperate troughs (TTTs: 3–7 days), and the intraseasonal variability associated with the Madden–Julien Oscillation (MJO: 30–60 days). At the IV timescale, the occurrence of large‐scale extremes is substantially higher during its wet phases thereby suggesting a 400% rise in the occurrence of large‐scale extremes as compared to its dry phases. At the QDV timescale, variability mostly relates to the modulation of small‐scale extremes during its wet phases. Teleconnections with global sea surface temperature (SST) confirm that La Niña conditions favour overall wet conditions and extremes in South Africa. The numbers of large‐scale extremes are consistently related to warmer SSTs in the North Atlantic, while their link with warmer Indian and tropical South Atlantic oceans is found to be statistically independent of the state of ENSO. At the subseasonal timescales, large‐scale extremes largely occur during three out of the seven convective regimes identified in the southern African region whereas small‐scale extremes are nearly equiprobable during all convective regimes. The occurrence of large‐scale extremes during continent‐rooted TTT is further enhanced during the locally wet phases of the MJO and is symmetrically weakened during its dry phases.