bluuebunny/crossref_metadata_2025_split huggingface dataset:
PSYCHOLOGICAL AND PEDAGOGICAL BASICS OF FORMING THE COMMUNICATIVE CULTURE OF FUTURE EDUCATORS OF IPE: AN INTERDISCIPLINARY APPROACH
Authors: Marchii-Dmytrash Tamara , Kyrsta Nataliia , Matishak Marianna 
Published: March 2023

The article focuses on the fact that in the process of professional training, it is necessary to ensure the proper level of forming of the communicative culture of future educators of institutions of preschool education (IPE), and also substantiates its psychological and pedagogical foundations in the context of an interdisciplinary approach. Various approaches to the interpretation of the concepts "culture of communication", "communication ethics", "communicative culture", "communicative competence" have been analyzed. In order to form the communicative culture of future teachers of IPE, it is important to implement a humanistic paradigm of education, which involves partnership interaction of participants in the educational process, student-centeredness in the broad sense, a variety of activities of education seekers, a personally oriented style of communication, interaction and benevolent demandingness. An interdisciplinary approach in the context of the researched problem ensures systematicity, integrity and integration of scientific knowledge for the effective forming of the communicative culture of future educators. The psychological foundations of the specified process during the study of the disciplines of the psychological-pedagogical cycle and the teaching methods of individual disciplines, taking into account the interdisciplinary approach, are determined, in particular, the enrichment of the content of educational components with relevant scientific knowledge about the essence of the concepts of "communication", "communicative culture", the study of age and individual-psychological features of communication with preschool age children, their parents and other persons of the educational process in the IPE, assimilation of rules and ethical norms of communication; the usage of interactive forms and methods of learning during mastering the program content of the disciplines; interaction of participants in the educational process on the basis of partner pedagogics. The main idea of the article is that the culture of speech is actively formed in preschool age children (phonetically and orthographically correct and clean pronunciation of sounds, words and phrases, mastering the cultural norm of language, etc.), accordingly, it is important that the teacher of IPE was a role model and perfectly possessed communicative culture.
Keywords: communicative culture, communication, future educator, institution of preschool education (IPE), professional training, interdisciplinary approach, institution of higher education, educational component, educational process.
TRAINING OF FUTURE MASTERS FOR PEDAGOGICAL ACTIVITIES IN THE INSTITUTIONS OF HIGHER EDUCATION BY MEANS OF EDUCATIONAL TRAININGS
Authors: Melnychuk Iryna 
Published: March 2023

The article deals with the problem of training of future masters of medicine, who did not have received a pedagogical education, for pedagogical activities. It has been generalized that optimal conditions in the described process is using modern pedagogical innovations, which make possible an integration of vocational (in particular, medical) training and pedagogical education, give an opportunity for future masters of medicine testing own professional knowledge, abilities and skills in pedagogical situations that simulate professional-pedagogical, medical-professional activities. Educational trainings may become such technologies. Analysis of scientific literature gave a possibility to generalize that scholars describe theory and practice, contextual and methodical aspects of conducting trainings, reveal the main stages of training technologies, propose methods of organization and conducting training of personal development, which gives an opportunity to identify the essence of trainings in general. The purpose and task of the research is to describe the essence of educational trainings, which appropriate to apply in the vocational training of future masters of medicine for pedagogical activities in the institutions of higher medical education. It has been generalized that in the process of participating the future masters of medicine in educational trainings, participants have ability to identify the main advantages of such work for the use of training forms and methods of teaching in pedagogical activity as a lecturer of medical institution of higher education. It has been stated that the purpose of training of future masters for participating and individual conducting educational trainings in pedagogical activities of lecturers must inform the participants with the main model of preparing for training, which is seen as the basis for making appropriate syllabus that combine the following stages: determining the topic and purpose of training as an image of the future result; determining the composition of the training group; identifying the time resources; formulating the problem; formulating the tasks; selecting appropriate exercises, situational tasks of professional purposes; emphasizing the blocks of the training syllabus and classes for each block; drawing up a scenario of training plan; writing a short training scenario with the purpose of each class and all the necessary materials.
Keywords: masters, vocational training, pedagogical activity, educational trainings, training requirements.
Race and Ethnicity Reporting and Representation in Pediatric Clinical Trials
Authors: Brewster Ryan C.L. , Steinberg Jecca R. , Magnani Christopher J. , Jackson Jasmyne , Wong Bonnie O. , Valikodath Nishma , MacDonald Justin , Li Anna , Marsland Paula , Goodman Steven N. , Schroeder Alan , Turner Brandon 
Published: March 2023

BACKGROUND AND OBJECTIVES
Representative enrollment of racial and ethnic minoritized populations in biomedical research ensures the generalizability of results and equitable access to novel therapies. Previous studies on pediatric clinical trial diversity are limited to subsets of journals or disciplines. We aimed to evaluate race and ethnicity reporting and representation in all US pediatric clinical trials on ClinicalTrials.gov.

METHODS
We performed a cross-sectional study of US-based clinical trials registered on ClinicalTrials.gov that enrolled participants aged &lt;18 years old between October 2007 and March 2020. We used descriptive statistics, compound annual growth rates, and multivariable logistic regression for data analysis. Estimates of US population statistics and disease burden were calculated with the US Census, Kids’ Inpatient Database, and National Survey of Children’s Health.

RESULTS
Among 1183 trials encompassing 405 376 participants, race and ethnicity reporting significantly increased from 27% in 2007 to 87% in 2018 (P &lt; .001). The median proportional enrollment of Asian American children was 0.6% (interquartile range [IQR], 0%–3.7%); American Indian, 0% (IQR, 0%–0%); Black, 12% (IQR, 2.9%–28.4%); Hispanic, 7.1% (IQR, 0%–18.6%); and white 66.4% (IQR, 41.5%–81.6%). Asian American, Black, and Hispanic participants were underrepresented relative to US population demographics. Compared with expected proportions based on disease prevalence and hospitalizations, Asian American and Hispanic participants were most consistently underrepresented across diagnoses.

CONCLUSIONS
While race and ethnicity reporting in pediatric clinical trials has improved, the representative enrollment of minoritized participants remains an ongoing challenge. Evidence-based and policy solutions are needed to address these disparities to advance biomedical innovation for all children.
Calidad del empleo y estructura del mercado de trabajo en América Latina desde una perspectiva comparada
Authors: Fernández-Franco Sebastián , Graña Juan , Lastra Facundo Martín , Weksler Guido 
Published: March 2023

Los aportes latinoamericanos a las teorías del mercado laboral destacan que la región se caracteriza por la existencia de una importante heterogeneidad productiva, que se expresa en la convivencia de unidades de muy variada productividad y calidad del empleo.
En este marco, este trabajo tiene dos objetivos. Primero, analizar la situación actual de los mercados de trabajo de América Latina de manera comparada. Para ello se estudia la calidad del empleo e ingresos de asalariados y no asalariados en 13 países latinoamericanos, trabajando con 9 perfiles ocupacionales construidos según calificación del puesto de trabajo y tamaño del establecimiento.
En segundo lugar, evaluar cuál es el nivel de deterioro del poder adquisitivo de los salarios de la región y su heterogeneidad entre perfiles. Para ello, se comparan los ingresos de éstos respecto a Estados Unidos, representante de los países desarrollados.
Los resultados confirman que los aportes de la literatura siguen vigentes y que los niveles salariales y de calidad del empleo promedio se encuentran marcadamente por debajo de los de Estados Unidos. Se concluye que el rezago productivo que caracteriza a la región se traduce en un deterioro general de las condiciones laborales, que se expresa con mayor fuerza en los pequeños establecimientos.
3D printed carbon-fiber filament density effects on mechanical properties
Authors: Hasan Samah Falah , Kadhim Fahad Mohanad , Muhammed Yasser 
Published: March 2023

AbstractThis study aims to select the suitable density of the material according to the mechanical properties needed by the 3D-printing application in which it will be used. 3D-printed carbon fiber filaments with different printing densities have been tensile, and a fatigue test was experimented with to find the mechanical properties. Furthermore, the modulus of elasticity, yield stress, and ultimate tensile strength of the material was determined by analyzing the stress-strain curves. The result shows that the parts printed with a high infill density give better mechanical properties, more time to build the object, more strength, and heavier weight than those printed with low infill density.
O USO DA TECNOLOGIA NA EDUCAÇÃO INCLUSIVA: CRENÇAS E PRÁTICAS DOCENTES
Authors: DO AMARAL OLIVEIRA JULIANA TEIXEIRA , Silva Andréa Imbiriba , Lellis Irani Lauer 
Published: March 2023

A escola é um ambiente de interação e aprendizado que está em constante transformação. Atualmente, fenômenos sociais, como o uso das novas tecnologias da educação e a inclusão do aluno com deficiência na sala de aula comum do ensino regular, estão cada vez mais presentes na escola. A presente pesquisa objetivou investigar as crenças de professores a partir do relato dos docentes sobre o uso de tecnologias em sala de aula comum do ensino regular nas escolas inclusivas. A amostra foi composta por 45 professores de 11 escolas da rede municipal de ensino fundamental. Os dados foram coletados por meio de questionário e entrevista individual e analisados utilizando-se o software Iramuteq. O software gerou dois eixos temáticos, subdivididos em quatro classes. Cada classe foi analisada separadamente. O estudo revelou que, para os professores, ainda são muitos os desafios na atuação com a educação inclusiva e com o uso das tecnologias. Verificou-se que os professores possuem crenças de que a educação inclusiva é importante e que o uso das tecnologias poderia favorecer o processo educativo dos alunos com deficiência. Foram identificados como crenças potencialmente facilitadoras em relação ao uso das tecnologias na educação inclusiva aspectos como: necessidade de melhora na estrutura da escola, mais recursos, formação básica e continuada e apoio do governo, tanto no que se refere à possibilidade de o professor ter acesso pessoal às tecnologias quanto à sua formação para lidar com a educação inclusiva e com as tecnologias da informação e comunicação.
TEZ YAZIMI İÇİN BİR REHBER: ONTOLOJİDEN METODOLOJİYE GENEL BİR BAKIŞ
Authors: KÖKALAN ÇIMRIN Füsun 
Published: March 2023

Sosyal bilimler alanında lisansüstü düzeyde tez araştırması yürütmek ve yazmak oldukça yoğun emek gerektiren bir süreç anlamına gelir. Dolayısıyla bu makalede lisansüstü düzeyde eğitim gören sosyal bilim öğrencilerini, geçerli ve güvenilir araştırma yapma hakkında bilgilendirmek ve onları bilimsel araştırmanın epistemolojik ve metodolojik ilkeleri konusunda bir yolculuğa çıkarmak amaçlanmıştır. Özellikle tez yazma aşamasında olan öğrenciler, bu çalışmanın ana okuyucu kitlesini oluşturmaktadır. Makalenin içeriği üç başlık altında toplanabilir. Bunlardan ilki, sosyal bilimsel bir araştırmanın dayandığı temel ontolojik, epistemolojik ve metodolojik ilkeleri sunmak ve bu üç unsur arasındaki gözden kaçan bağlantıyı görünür kılmaktır. İkinci olarak özellikle genç araştırmacılar açısından çoğu zaman kafa karışıklığı yaratan bazı temel kavramları (yöntem, teknik, desen vb.) açıklığa kavuşturmaktır. Bir sonraki tartışma ise tezin araştırma konusunun ve sorusunun seçimine yöneliktir.
Sosyal bilimler alanında oldukça geniş bir yelpazeyi kapsayan metodolojik ilke ve kuralların tümüne odaklanmayan bu çalışmanın temel kurgusu, araştırma sürecine yeni başlayanlar için bir perspektif oluşturmaktır. Özellikle de sosyal bilimsel araştırmanın bilim felsefesi temeli üzerine odaklanılmıştır.
GÜNDEM BELİRLEME VE ÇERÇEVELEME TEORİLERİ BAĞLAMINDA TASS VE UKRİNFORM HABER AJANSLARININ RUSYA-UKRAYNA SAVAŞ SUNUMLARININ İNCELENMESİ
Authors: TOKGÖZ Emircan , İMİK TANYILDIZI Nural 
Published: March 2023

Gündem belirleme teorisi, haber medyasında sıklıkla tekrarlanarak öne çıkarılan konuların ve bu konuların anlatım tarzlarının kamuoyu, medya ve siyaset gündemlerini etkileyebildiğini ileri sürmektedir. Bu tez, alanda yapılmış çalışmalarla defalarca doğrulanmıştır. Gündem belirleme, çerçeveleme teorisiyle birlikte, medya etkilerinin en önemli teorilerindendir. Bu teoriler haber medyasında gündem konularının seçilerek oluşturulduğunu vurgulamaktadır. Seçilerek aktarılan kamu sorunları veya özenle hikâyeleştirilen diğer herhangi bir haber nesnesi, kamuoyunun olay ve olgulara ilişkin bakışını şekillendirebilmektedir.
Bu çalışmada, haber medyasının en tepesinde yer alan haber ajanslarının Rusya-Ukrayna savaşını sunumları gündem belirleme ve çerçeveleme teorileri kapsamında araştırılmıştır. Rus haber ajansı TASS ve Ukrayna haber ajansı Ukrinform savaşan ülkelere ait ajanslar olarak seçilmiştir. Savaşın ilk günü yayınladıkları ilk yüz haber incelenmiştir. Araştırmada içerik analizi yöntemi kullanılmıştır. Analizler sonucunda, ajansların savaşla ilgili konuları farklı hikâyelerle aktardıkları tespit edilmiştir.
Modelo didáctico para la redacción de textos expositivos académicos por estudiantes universitarios
Authors: Tineo Tiquillahuanca Alcides 
Published: March 2023

Debido que la escritura es una habilidad de alta demanda en los contextos académicos y científicos, el objetivo de esta investigación fue determinar la influencia de un programa de escritura en la capacidad para escribir un texto expositivo académico por parte de estudiantes universitarios del primer ciclo. El programa se elaboró a partir de un modelo didáctico de escritura, propuesto por el mismo autor. El tipo de investigación es aplicada, con enfoque cuantitativo, y sigue un diseño preexperimental. La muestra estuvo conformada por 176 estudiantes del primer ciclo de cuatro programas o carreras profesionales. La recolección de datos se realizó mediante una rúbrica que demandó la redacción de un texto expositivo académico. Los resultados demostraron que el programa basado en el modelo didáctico mejoró significativamente la competencia escritural de los estudiantes universitarios, mediante la prueba estadística de Kruskal-Wallis, con un p valor de 0,000 (p<0,05).
DISCOVERY OF DONEPEZIL-LIKE COMPOUNDS AS POTENTIAL ACETYLCHOLINESTERASE INHIBITORS DETERMINED BY PHARMACOPHORE MAPPING-BASED VIRTUAL SCREENING AND MOLECULAR DOCKING
Authors: CÖMERT ÖNDER Ferah 
Published: March 2023

Objective
Alzheimer's disease (AD) is the most common cause
of dementia in older people due to abnormalities in
the cholinergic system. Acetylcholinesterase has
an important role in the regulation of the cholinergic
system. Therefore, targeting AChE is one of the most
promising strategies for the treatment of AD. Although
several approved drugs to treat AD, it is still needed
to develop potential inhibitor candidates. Therefore,
the aim of this study is to discover newly donepezillike
natural compounds and their synthetic derivatives
targeting acetylcholinesterase enzyme (AChE).
Material and Method
A pharmacophore model of a known drug, donepezil
was generated. Using the pharmacophore mapping
module of the Discovery Studio 2021 program,
the chemical library containing natural products
and synthetic derivatives was screened. The
pharmacokinetics and drug-likeness properties of the
screened compounds were predicted by ADMET and
Lipinski and Veber’s rule. Some criteria were used as a
filter. In addition, bioactive compounds of the database
were screened. Then, molecular docking study was
performed by using Glide/SP of Maestro (Schrödinger,
Inc.) to determine the potential molecules.
Results
The binding energies were determined for hit
compounds after molecular modeling studies.
Furthermore, H-bonding, pi-pi stacking, pi-cation,
and pi-alkyl interactions between the protein-ligand
complex have been identified by various amino acid
residues such as Tyr, Asp, His, Trp, Arg. The results
show that the potential compounds are a promising
candidate with binding energy compared to donepezil.
The molecular modeling results indicate that new
scaffolds may contribute to the discovery of new AChE
inhibitors compared to a reference drug.
Conclusion
This study may lead to further studies and contribute to
examination with in vitro analysis. The scaffolds can be
used to design novel and effective inhibitors.
Implicaciones farmacológicas de los receptores activados por los proliferadores de peroxisomas
Authors: Parra Sergio , Mejía Rivera Luis Carlos 
Published: March 2023

Los receptores activados por los proliferadores de peroxisomas (PPAR) son un grupo de proteínas pertenecientes a la familia de receptores de ubicación nuclear que se comportan como factores que modulan la transcripción del DNA al unirse a elementos de respuesta específicos de ciertos genes blanco. Hasta el momento se han descrito tres tipos principales de PPAR designados como a, d, y g; estos receptores se encuentran involucrados en la regulación de diferentes procesos metabólicos; por esto se han convertido en uno de los grupos de receptores más intensamente estudiados. Los PPARa participan tanto en el catabolismo de los ácidos grasos como en el transporte extracelular de lípidos; los fibratos, sus agonistas, tienen utilidad ampliamente demostrada en el manejo de algunas dislipidemias. Las tiazolidindionas utilizadas como fármacos antihiperglicemiantes son agonistas de los PPARg; todavía existen muchos interrogantes acerca de su relación con el metabolismo de los carbohidratos pero su uso en el manejo de la diabetes mellitus tipo 2 cada vez gana más importancia. Por otro lado, los antiinflamatorios no esteroideos se relacionan de alguna manera con las funciones de los PPARd; hasta el momento se ha logrado establecer una relación molecular y epidemiológica de estos fármacos y receptores con el cáncer de colon.
Structural Model of the Association between Spiritual Health and Self-Esteem of Students in Yazd Farhangian University with the Mediating Role of General Health
Authors: Zare Jamalabadi Mahmoud , Afshani Seyed Alireza 
Published: March 2023

Background: Spiritual and mental health is among the components affecting self-esteem as one of the key and necessary characteristics of every teacher. This study was aimed at examining the association between spiritual health and self-esteem of students of Yazd Farhangian University with the mediating role of general health in the academic year 2020-2021.
Methods: This was a analytical cross sectional study with the statistical population of all students and teachers of Yazd Farhangian University, including 323 people selected as a sample based on Cochran’s formula. Research data were gathered through using the Paloutzian, R. F., & Ellison, C. W. Loneliness, Spiritual, and Well-being Scale, Goldberg General Health Questionnaire (GHQ-28), and The Coopersmith Self-Esteem Inventory (CSEI). To analyze the research data, Pearson correlation coefficient, covariance-based structural equation modeling (CB-SEM), bootstrapping technique, and fit indices for structural equation modeling were employed using softwares of SPSS and AMOS at a significance level of less than 0.05.
Results: The findings revealed a positive and significant correlation between spiritual health and general health (0/316, p<0/001), as well as between general health and self-esteem (0/423, p<0/001). Furthermore, there was a positive and significant association between spiritual health and self-esteem (0/339, p<0/01). Moreover, the findings emphasized the significance of the general health’s mediating role between the spiritual health and self-esteem variables.
Conclusions: Considering the significance , positive and strong relationship between spiritual health and general health as well as self-esteem, it is recommended that to enhance the adolescents’ spiritual and general health and increase their self-esteem, educational programs should be revised and more attention should be paid to attracting Farhangian University students.
Interdisciplinaridade e as múltiplas dimensões do trabalho em saúde
Authors: Costa Lucilene Alves Pereira , Nunes Nilza Rogéria de Andrade , Mendes Rosilda 
Published: March 2023

Este artigo tem como objetivo analisar criticamente a interdisciplinaridade e a forma como é compreendida e implementada no trabalho em saúde. A coleta de dados se deu através de pesquisa bibliográfica e revisão integrativa de artigos científicos na área de saúde em periódicos indexados nas bases de dados SCIELO, BVS, LILACS, PUBMED, publicados no período entre janeiro de 2007 a dezembro de 2020. Identificou-se a ausência de consenso sobre o conceito e verificou-se que a temática perpassa diferentes áreas do saber. Os resultados foram organizados em dois núcleos: a interdisciplinaridade na formação acadêmica e na atuação profissional. Dentre as evidências constatou-se que embora o trabalho em saúde tenha como princípio norteador o cuidado integral, e as Diretrizes Curriculares Nacionais primem por uma formação interdisciplinar, ainda é preponderante nos cursos de graduação relacionados à saúde os currículos pautados em disciplinas, o que reflete em práticas desarticuladas e isoladas. Conclui-se que práticas interdisciplinares em consonância com o princípio da integralidade das ações em saúde se tornam cada vez mais necessárias, tanto para manutenção do diálogo entre os diferentes campos do conhecimento e o fortalecimento das relações profissionais, quanto para melhor responder às necessidades de saúde.