bluuebunny/crossref_metadata_2025_split huggingface dataset:
Possibility to transfer of biological activities compounds by liposomes
Authors: Tsedevsuren Bolortsetseg , Sanjdorj Enkhmart , Byambajav Bilguun , Darisuren Maral-Erdene , Tulgaa Enkh-Oyun , Burenjargal Munkhjargal , Davaanyam Budragchaa 
Published: December 2022

Research on the use of liposomes as a carrier of bio-active compounds has been carried out extensively due to that liposome-carried drugs have more than 80% activity in reaching target cells.
In this study, we conducted research on the possibility of using phospholipids to convert oil and water-insoluble compounds with biological activities into water-based compounds. This will allow to introduce the advancements in liposomal delivery of medicinal products practice of human medicine to the veterinary medicine as a promising approach.
We prepared liposome extract from egg yolk, then 0.5 ml of 5% potassium-iodine and 0.3 g of cur cumin were transported to the liposome by ultra-sonication method. The measurements of an electron microscope at 500 nm indicate that a spherical phospholipids were formed successfully. As a result of FT-IR spectrophotometry, functional groups of fatty acids were detected at 3400 cm-1, C-H at 2973 cm-1, C=O at 1730 cm-1, and C-O at 1220 cm-1. The ratio of saturated and unsaturated fatty acids by gas chromatography (GC/MS) was 60.44% and 37.91% in white eggs, while 39.41% and 62.02% in brown eggs, respectively.
Биологийн идэвхтэй нэгдлийг липосом ашиглан зөөвөрлөх боломж
Хураангуй
Липосомыг био-идэвхит нэгдлийн зөөвөрлөгч болгон ашиглах судалгаа өргөнөөр хийгдэж, шахмал эмийн үйлчлэх идэвх 20%, тарилга 70%-ийн идэвхтэй байдаг бол липосомоор зөөвөрлөгдсөн тэдгээр нэгдлийн бай эсэд хүрч очин 80-аас дээш хувийн идэвх үзүүлдэг байна. Бид энэхүү судалгаагаар липосом ашиглан тосон суурьт болон усанд уусдаггүй биологийн идэвхтэй нэгдлүүдийг зөөвөрлөх боломжийг судаллаа. Ингэснээр хүн эмнэлгийн анагаах ухаанд нэвтрээд буй липосом ашиглах аргыг мал эмнэлгийн хэрэглээнд нэвтрүүлэх боломж нээгдэх юм.
Туршилтанд 0.5 мл 5%-ын кали-иодын тос ашиглан липосомоор зөөвөрлөх туршилтыг явуулахад уусмал нэгэн жигд хөөсөрсөн бол 0.3 г куркумин хуурай бодисны хувьд тунадас бага үүсгэж байсан нь липосомоор зөөвөрлөгдөх боломжтойг харуулж байна. Бүтцийн анализ хийсэн FT-IR спектрофотометрийн үр дүнд 3400 см-1 утганд –ОН групп, 2973 см-1 утганд С-Н, 1730 см-1 утганд С=О, 1220 см-1 утганд С-О тосны хүчлийн функциональ бүлгүүд илэрсэн. Электрон микроскопын 500 нм хэмжилтэд фосфолипид бөмбөлөг үүссэн нь липосом мөн болохыг илтгэж байна. Масс спектрийн хийн хроматографийн (GC/MS) аргаар ханасан болон ханаагүй тосны хүчлийн харьцааг тодорхойлоход цагаан өндгөнд 60.44% ба 37.91%, бор өндгөнд 39.41% ба 62.02% тус тус байв. Таньцын туршилтаар биологийн идэвхит нэгдлийг тээвэрлэх боломжтой нь тогтоогдлоо.
Түлхүүр үг: Өндөгний шар, фосфолипид, липосом, тосон суурьт нэгдэл, куркумин
МЕКТЕПКЕ ЧЕЙИНКИ БАЛДАРДЫ ЭМГЕККЕ ТАРБИЯЛОО
Authors: Нишанбаева Мерниса 
Published: December 2022

Мектепке чейинки курактагы балдарды эмгекке тарбиялоодо жаш өзгөчөлүгүнө карата бөлүнөт. Мектепке чейинки курактагы балдарды тарбиялоодо күндөлүк турмушундагы эн жөнөкөй эмгекке тарбиялоо зарыл деп эсептелет. Эмгекке тарбиялоо менен балдардын көптөгөн иш- аракети, жөндөмүү өнүгөт. Эрте курактагы балдарды эмгекке тарбиялоо учурунда аларга көрсөтмөлүү жана жеңил жумуштун түрлөрү менен тааныштырылат. Мына ушунун натыйжасында балдардын активдүүлүккө, акылдуулуука, аракетчил, тапкыч, иштерман жана максатына жетүүгө үйрөнүшөт. Ар дайым балдар эмгек жасоо аракетине чоң адамдардын, тарбиячылардын, ата-энелердин жардамы негизги орунда турат. Баланы эмгек ишмердүүлүгүдө даярдоодо жаш өзгөчөлүгү эске алынат жана эмгектин түрлөрүн жасоого тарбияланат. Анткени мектепке чейинки курактагы балдар өз алдынча эмгек жасоого тарбияланат жана бирдиктиктүү иш жасоого үйрөнөт. Алардын эмгек менен таанышууда тарбиячылардын колдоосу астында жүргүзүлөт. Мектепке чейинки мекемелерде жаш курагына карата тайпаларга бөлүнүшөт жана эмгекке болгон кызыгуусу арттыруу максатында ар түрдүү оюн ишмердүүлүгүн уюштуруу менен иш жүзүнө ашырылат. Эрте курактагы балдардын мүмкүнчүлүгүнө жараша эмгектин түрү таңдалып алынат жана тарбиячылар чоң адамдар менен бирге эмгек жасоого көмөк көрсөтүүлөт.
Pengaruh E-Money Terhadap Perilaku Konsumtif dengan Kontrol Diri Sebagai Variabel Intervening
Authors: Layaman Layaman , Khairunnisa Hafni , Rohayati Risa 
Published: December 2022

Pengaruh perilaku konsumtif mahasiswa dipengaruhi oleh beberapa faktor. Dalam penelitian ini faktor yang diduga mempengaruhi perilaku konsumtif adalah penggunaan e-money dan kontrol diri. Tujuan penelitian ini adalah untuk mengetahui pengaruh e-money terhadap perilaku konsumtif dengan kontrol diri sebagai variabel intervening pada mahasiswa Fakultas Syariah dan Ekonomi Islam (FSEI) Institut Agama Islam Negeri (IAIN) Syekh Nurjati Cirebon. Subjek penelitian ini adalah Mahasiswa Fakultas Syariah dan Ekonomi Islam (FSEI) Institut Agama Islam Negeri (IAIN) Syekh Nurjati Cirebon. Populasi dalam penelitian ini berjumlah 3.539 mahasiswa. Jumlah sampel dalam penelitian ini adalah 97 mahasiswa dihitung dengan rumus slovin dengan taraf kesalahan 10%. Metode analisis data yang digunakan adalah regresi linier berganda menggunakan spss versi 22. Hasil penelitian ini menunjukkan bahwa e-money berpengaruh terhadap perilaku konsumtif, e-money berpengaruh terhadap kontrol diri, kontrol diri tidak berpengaruh terhadap perilaku konsumtif dan kontrol diri mampu memediasi antara e-money dan perilaku konsumtif pada Mahasiswa Faklultas Syariah dan Ekonomi Islam (FSEI) Instutut Agama Islam Negeri (IAIN) Syekh Nurjati Cirebon.
Ekonomik Kalkınma, Rekabet ve İnovasyon İlişkisinin Panel Veri Analizi ile İncelenmesi: G20 Ülkeleri Örneği
Authors: GÜNDÜZ Murat , PARLAK Nazlı 
Published: December 2022

İktisadi kalkınma olgusunun ölçülmesinde ülkelerin ekonomik, demografik, sosyal, kültürel ve siyasal yapılarında meydana gelen farklılıkların bulunması bu kavramın tek bir ölçütle belirlenmesine engel olmaktadır. Bu durumda insani gelişme raporunda da belirtildiği gibi kalkınmanın amaçları ve araçları arasında temel bir ayrımın yapılmasını zorunlu kılmaktadır. Kalkınma ekolü gelişme ekonomisi olarak da adlandırılmakta ve ‘ekonomik büyüme’ ve ‘insani gelişme’ olmak üzere iki ayrı çerçevede incelenmektedir. Günümüzde teknolojik alanda meydana gelen gelişmeler; ekonomik gelişimin tetikleyici, insani gelişiminde itici gücü olmaktadır. Küresel piyasalarda ülkeler elde ettikleri bu güç doğrultusunda orta ve uzun vadede üstünlük elde etme ve rekabetçi yapılarını da koruma arzusu içindedirler.
Ekonomide kalkınma kavramı, inovasyon kavramı ve rekabet gücü kavramları arasında domino etkisi söz konusudur. Şöyle ki inovatif bir ülkede yaşanan gelişmeler rekabet gücünü arttırmakta, rekabet gücü ve inovasyon içeren ülkelerde kalkınmaktadır. Kalkınma gelişmekte olan ülkeler için önemli bir süreçtir. Bu süreç içerisindeki ekonomik hamlelerin doğru atılması, gelişmekte olan ülkelerin gelişmiş ülke seviyesine yükselmesinde ve toplumsal refah elde etmesinde büyük önem taşımaktadır.
Bu çalışmada gelişmekte olan G-20 ülkelerinde rekabet ve inovasyon değişkenlerinin ekonomik kalkınma ilişkisinin panel veri analizi kullanılarak araştırılması amaçlanmaktadır. Bu amaç doğrultusunda verisine ulaşılabilinen 13 G-20 ülkesi 1997-2018 dönemleri arasında incelenmiştir. Çalışmada panel veri analizi tekniklerinden yararlanılmıştır. Çalışma sonuçlarına göre; ekonomik kalkınma ile rekabet ve inovasyon değişkenlerinin uzun dönende ilişkili oldukları ve bu değişkenler arasında pozitif nedensel ilişkinin bulunduğu sonucuna ulaşılmıştır.
A Portrait of Teaching and Learning Speaking Strategy at Eighth Grade of English Extracurricular
Authors: Alfiyah Ririn , Zaeni Ahmad 
Published: December 2022

Toddlers have behavioral styles or temperaments that affect sensory and motor interactions. This The aim of this research is to know teaching and learning speaking process in English extracurricular in (Sekolah Menengah Pertama/Junior High School). The method which used in this research is qualitative research. The techniques of collecting data that the researcher used are in depth observation and in dept interview to know about teaching and learning speaking in The EAST class as English extracurricular program. The result of this research shows that teaching and learning speaking process in English extracurricular program is good, because it does with appropirate approach, method, and technique that the tutors used are suitable to the students needed. Therefor, the students have good progress in learning speaking English. The researcher recommend this extracurricular program to be followed by other schools. Because the researcher saw, in common, people have an assumption that a person who master in foreign language is a person who can speak its language. Speaking is interpreted as a fundamental subject for students develop a successful communication in language itself, which is often the main aim of learning any foreign language. It takes place that teaching speaking has a fundamental position to teacher helps students in learning speaking English. Therefor, teaching and learning speaking has became important for teachers and students to get the aims of speaking, those are to communicate and interact to others.
Speaking Problems in Vocational High School
Authors: Hervinna Febriani Sitorus  , Putri Vaniarisa Sinaga  , Syntia Devi Lumban Gaol  , Rosalina Imelda Octaviana Situmorang  , Selviana Napitupulu  
Published: December 2022

This study aims to find the difficulties when speaking English which are mostly faced by vocational students. This study used qualitative research methods. This research instrument is observation and interviews. Based on the results of the observation and interviews, it was found that students found speaking difficulties like (1) pause, (2) fillers, (3) mental problems, (4) lack of ideas, (5) grammatical error, (6) poor vocabulary. Speaking skill is very important for us because serves to maintain and establish social relations, and the transactional functions, which focus on the exchange of the informations. Therefore, it is necessary to conduct research to solve the problem of speaking difficulties experienced by students, so that there are improvements for the future and students' speaking skills are increasing
Simultaneous Realization of Good Piezoelectric and Strain Temperature Stability via the Synergic Contribution from Multilayer Design and Rare Earth Doping
Authors: Zhang Yumin , Yu Yungang , Zhang Nan , Zheng Ting , Wu Jiagang 
Published: December 2022

AbstractNiobate‐based lead‐free piezoceramics have attracted wide attention due to their excellent piezoelectric properties. Although the temperature sensitivity of piezoelectricity or strain in one sample has been solved to a certain extent, how to simultaneously improve the temperature stability of both in one sample is still an issue. Herein, by constructing multilayer composite ceramics and doping Ho element, both improved piezoelectric and strain temperature stability (the variations are below 3% under 30–100 °C) are achieved, showing great property advantage compared with previous reports. Different from the compositionally graded composite ceramic design, the Ho doping can not only increase orthorhombic‐tetragonal phase transition temperature (TO‐T) and then create the condition for the formation of successive phase transition, but also stabilize the oriented domain state. Therefore, the excellent temperature stability of both piezoelectricity and strain can be attributed to the multistep phase transition induced by the multilayer design, the fine regulation of TO‐T interval by the optimization of lamination combination, and the stabilized polarization induced by Ho doping. The new strategy for solving both piezoelectric and strain temperature sensitivity can further promote the commercial application of potassium sodium niobate‐based lead‐free piezoelectric ceramics.
Recent Advances in Stimuli‐Responsive Smart Membranes for Nanofiltration
Authors: Yu Dehao , Xiao Xiao , Shokoohi Cyrus , Wang Yanxin , Sun Liyue , Juan Zhaoge , Kipper Matt J. , Tang Jianguo , Huang Linjun , Han Gill Sang , Jung Hyun Suk , Chen Jun 
Published: December 2022

AbstractNanofiltration membrane plays an increasingly important role in many industrial applications, such as water treatment and resource recovery. The performance of the smart nanofiltration membrane is largely controlled by pore size, the Donnan effect, and surface wettability, which are determined by the function of stimuli‐responsive components. Smart membranes, which contain stimuli‐responsive components, are capable of changing their physical and chemical properties in response to changes in the environment so that the microstructure of the membrane will have more efficient performances and broader application prospects than the current traditional nanofiltration membranes. Herein, the preparation methods of stimuli‐responsive membranes are described and they are systematically classified accordingly to their mechanisms. Moreover, the latest progress of stimuli‐responsive membranes in nanofiltration and the main mechanism of each stimuli‐response type through relevant examples are discussed and summarized. Finally, this review provides new insights into the remaining challenges and future directions of stimuli‐responsive membranes. Fueled by advances in chemistry and materials science, it is expected to build a smart and efficient nanofiltration membrane platform for the benefit of mankind.
An Ultrafast and Stable Li‐Metal Battery Cycled at −40 °C
Authors: Cheng Liwei , Wang Yingyu , Yang Jie , Tang Mengyao , Zhang Chenguang , Zhu Qiaonan , Wang Sicong , Li Yuting , Hu Pengfei , Wang Hua 
Published: December 2022

AbstractLi‐metal battery (LMB) suffers from the unexpected Li dendrite growth and unstable solid‐electrolyte interphase (SEI), especially in the extreme conditions, such as high rates and low temperatures (LT). Herein, a high‐rate and stable LT LMB is realized by regulating electrolyte chemistry. A weak Li+‐solvating solvent 2‐methyltetrahydrofuran is used as electrolyte solvent to mitigate the kinetic barrier for Li+ de‐solvation. Moreover, a co‐solvent tetrahydrofuran with a high donor number is incorporated to improve the LT solubility of Li salts, achieving an improved ionic conductivity while maintaining the weak Li+‐solvation effect. Furthermore, abundant FSI‐ anions in contact‐ion pairs are presented, facilitating the formation of a stable LiF‐enriched SEI. Consequently, the Li||Li battery can be operated at 10 mA cm‐2 with a small polarization of 154 mV at −40 °C. Meanwhile, an outstanding cumulative cycling capacity of 4000 mAh cm‐2 at 8.0 mA cm‐2 is achieved, reaching a record high level in LT alkali metal symmetric batteries. Also, rechargeable high‐rate and stable full batteries are achieved at −40 °C. This work demonstrates the superiority of electrolyte chemistry for synergistic regulation of both ion transfer kinetics and SEI toward ultrafast and stable rechargeable LMBs at LT.
First‐Principles Study on Interfacial Bonding Characteristics and Tensile Deformation Behavior of Ni (001)/Ni3Al (001) in K418 Superalloy
Authors: Wang Qin , Liu Furong , Lin Xin , Song Jinxia , Feng Haoyuan 
Published: December 2022

AbstractIn order to theoretically explore the interfacial bonding properties between the main phase (γ) and the second precipitated phase (γ') in K418 superalloy formed by direct laser deposition. First‐principles calculation is utilized to study the adhesion work, interfacial energy, electronic structure, bonding properties, and tensile properties between γ phase (Ni (001)) and γ' phase (Ni3Al (001)). The results show that the interface energy of the NiAl‐center (0.35–1.19 J m−2) is the smallest and therefore it is with the highest interface bonding strength. The electronic analysis suggests that strong Ni‐Al covalent and ionic bonds as well as Ni‐Ni metal bonds at the interface of the NiAl‐center model are formed with the appearance of obvious orbital hybridization. The yield strength of the NiAl‐top model reaches up to 19.38 GPa under the uniaxial tensile test, which is further increased when doped with those atoms of Re, Ta, and W, up to 20.38, 20.42, and 20.93 GPa, respectively. A fundamental understanding is presented here for the design of superalloys.
A Self‐Sustaining Antioxidant Strategy for Effective Treatment of Myocardial Infarction
Authors: Sun Quan , Ma Hongqin , Zhang Jiaxiong , You Baiyang , Gong Xiaohui , Zhou Xiaolin , Chen Jin , Zhang Guogang , Huang Jia , Huang Qiong , Yang Yurong , Ai Kelong , Bai Yongping 
Published: December 2022

AbstractMyocardial infarction (MI) is the leading cause of death worldwide and can lead to the loss of cardiac function and heart failure. Reactive oxygen species (ROS) play a key role in the pathological progression of MI. The levels and effects of ROS are significantly different in three unique pathological stages of MI, and most antioxidants cannot make corresponding adjustments to eliminate ROS, which leads to a great compromise to treat MI with antioxidants. Herein, an innovative self‐sustaining antioxidant strategy is developed to treat MI with self‐sustaining selenium‐embedded nanoparticles (SSSe NPs). SSSe NPs possess unique self‐sustaining antioxidant effects at different pathological stages of MI. This strategy of on‐demand ROS elimination during different pathological stages demonstrated excellent MI treatment efficacy and effectively reversed heart failure to normal heart function. The therapeutic mechanism of SSSe NPs is intensively investigated through a series of experiments and mainly involved five critical aspects of myocardial repair: protecting mitochondria, reducing cardiomyocyte apoptosis and ferroptosis, reducing inflammation and fibrosis, and promoting angiogenesis. This strategy not only provides a promising treatment option for MI but also offers inspiration for other ischemic diseases.
A Class of Organic Units Featuring Matrix‐Controlled Color‐Tunable Ultralong Organic Room Temperature Phosphorescence
Authors: Zhang Xue , Qian Chen , Ma Zhimin , Fu Xiaohua , Li Zewei , Jin Huiwen , Chen Mingxing , Jiang Hong , Ma Zhiyong 
Published: December 2022

AbstractA novel class of organic units (N‐1 and N‐2) and their derivatives (PNNA‐1 and PNNA‐2) with excellent property of ultralong organic room temperature phosphorescence (UORTP) is reported. In this work, N‐1, N‐2, and their derivatives function as the guests, while organic powders (PNCz, BBP, DBT) and polymethyl methacrylate (PMMA) serve as the host matrixes. Amazingly, the color of phosphorescence can be tuned in different states or by varying the host matrixes. At 77 K, all molecules show green afterglow in the monomer state but yellow afterglow in the aggregated state because strong intermolecular interactions exist in the self‐aggregate and induce a redshift of the afterglow. In particular, PNNA‐1 and PNNA‐2 demonstrate distinctive photoactivated green UORTP in the PMMA film owing to the generation of their cation radicals. Whereas the PNNA‐1@PNCz and PNNA‐2@PNCz doping powders give out yellow UORTP, showing matrix‐controlled color‐tunable UORTP. In PNCz, the cation radicals of PNNA‐1 and PNNA‐2 can stay stably and form strong intermolecular interactions with PNCz, leading to a redshift of ultralong phosphorescence.
Disentangling the components of pollen limitation in a widespread herb with gametophytic self‐incompatibility
Authors: Cisternas‐Fuentes Anita , Dwyer Roslynn , Johnson Nicole , Finnell Lindsay , Gilman Jeffrey , Koski Matthew H. 
Published: December 2022

AbstractPremiseSeed production is frequently limited by the receipt of insufficient or low‐quality pollen, collectively termed “pollen limitation” (PL). In taxa with gametophytic self‐incompatibility (GSI), incompatible pollen can germinate on stigmas but pollen tubes are arrested in styles. This allows for estimates of pollen performance before, during, and after self‐recognition, as well as insight into the factors underlying pollen quality limitation in GSI taxa.MethodsWe scored pollen performance following self and outcross pollinations in Argentina anserina to identify the location of self‐recognition and establish the relationship between pollen tubes and seed production. We then estimated quantity and quality components of PL from >3300 field‐collected styles. We combined our results with other studies to test the prediction that low pollen quality, but not quantity, drives higher PL in self‐incompatible (SI) taxa than in self‐compatible taxa (SC).ResultsSelf and outcross pollen germinated readily on stigmas, but 96% of germinated self‐pollen was arrested during early tube elongation. Reproduction in the field was more limited by pollen quality than by quantity, and pollen failure near the location of self‐recognition was a stronger barrier to fertilization than pollen germination. Across 26 taxa, SI species experienced stronger pollen quality, but not quantity, limitation than SC species.ConclusionsEvaluating pollen performance at multiple points within pistils can elucidate potential causes of pollen quality limitation. The receipt of incompatible pollen inhibits fertilization success more than insufficient pollen receipt or poor pollen germination in A. anserina. Likewise, pollen quality limitation drives high overall PL in other SI taxa.
Differences in individual flowering time change pollen limitation and seed set in three montane wildflowers
Authors: Schiffer Annie , Loy Xingwen , Morozumi Connor , Brosi Berry J. 
Published: December 2022

AbstractPremiseChanges to flowering time caused by climate change could affects plant fecundity, but studies that compare the individual‐level responses of phenologically distinct, co‐occurring species are lacking. We assessed how variation in floral phenology affects the fecundity of individuals from three montane species with different seasonal flowering times, including in snowmelt acceleration treatments to increase variability in phenology.MethodsWe collected floral phenology and seed set data for individuals of three montane plant species (Mertensia fusiformis, Delphinium nuttallianum, Potentilla pulcherrima). To examine the drivers of seed set, we measured conspecific floral density and conducted pollen limitation experiments to isolate pollination function. We advanced the phenology of plant communities in a controlled large‐scale snowmelt acceleration experiment.ResultsDifferences in individual phenology relative to the rest of the population affected fecundity in our focal species, but effects were species‐specific. For our early‐season species, individuals that bloomed later than the population peak bloom had increased fecundity, while for our midseason species, simply blooming before or after the population peak increased individual fecundity. For our late‐season species, blooming earlier than the population peak increased fecundity. The early and midseason species were pollen‐limited, and conspecific density affected seed set only for our early‐season species.ConclusionsOur study shows that variation in individual phenology affects fecundity in three phenologically distinct montane species, and that pollen limitation may be more influential than conspecific density. Our results suggest that individual‐level changes in phenology are important to consider for understanding plant reproductive success.