bluuebunny/crossref_metadata_2025_split huggingface dataset:
Safety of hyperbaric oxygen therapy in non-emergent patients with a history of seizures: A retrospective cohort study
Authors: Park Subin , Marinov Anton , Clarke Hance , Schiavo Simone , Greer Elise , Djaiani George , Tarshis Jordan , Katznelson Rita 
Published: January 2025

Background
Hyperbaric oxygen therapy (HBOT) is well established as a treatment for various medical conditions. However, it poses a risk of oxygen toxicity, which can cause seizures particularly in individuals with pre-existing seizure disorders. Consequently, seizure disorders are considered a relative contraindication to HBOT. Despite this, the relative risk of HBOT-induced seizures in this patient population remains unclear. This retrospective cohort study aims to evaluate the safety of HBOT among patients with pre-existing seizure disorders.

Methods
After obtaining approval from the Research Ethics Board, we retrospectively reviewed the patient charts of individuals with a history of seizures who were referred to the Rouge Valley Hyperbaric Medical Center and Toronto General Hyperbaric Medicine Unit for HBOT between January 2020 and December 2023. Relevant demographic information, past medical history, and HBOT session treatment protocols, such as the treatment pressure set in absolute atmospheric pressure (ATA) and number of air breaks, were recorded. The collected data was analyzed using descriptive statistics.

Results
A total of 43 patients were referred to HBOT during the study period, and 21 patients did not proceed with the treatments. In total, 634 HBOT sessions were administered to 22 patients in monoplace chambers with five-minute air breaks, and one patient experienced a seizure event. Each patient completed an average of 29 (range 3–60) sessions lasting 90–120 minutes at 1.8 ATA (n = 3), 2.0 ATA (n = 18), or 2.4 ATA (n = 1). Fifteen patients were on oral antiseizure medications during the HBOT course. The overall incidence of seizures was one in 634 treatments.

Conclusion
While patients with a history of seizures may develop seizure activity during HBOT, the majority can safely undergo treatment when predetermined protocols are followed. With careful management and adherence to established protocols, HBOT can be a viable treatment option for those with seizure histories.
Rodríguez Gutiérrez, M. (2023). Las poetas cubanas: lo cubano, lo contemporáneo. Peter Lang.
Authors: Pérez Cabaña Rosario 
Published: January 2025

Reseña de Rosario Pérez Cabaña: Rodríguez Gutiérrez, M. (2023). Las poetas cubanas: lo cubano, lo contemporáneo. New York: Peter Lang. 217 pp. ISBN 978-1-4331-8814-5.
Kreolskość Bronisławy Wajs i komparatystyka literacka w Polsce
Authors: Kledzik Emilia 
Published: January 2025

Artykuł stanowi próbę zilustrowania przy pomocy lokalnego przykładu lterackiego najnowszych teorii komparatystycznych, które zrównują studia porównawcze z badaniami nad przekładem. Posługując się kategorią niewspółmierności i figurą Kreola z prac Emily Apter oraz refleksją nad językami kreolskimi Edouarda Glissanta, analizuje oryginalne wersje utworów romskiej poetki Bronisławy Wajs (Papuszy). Utwory Wajs do 2020 roku były znane czytelnikom w wersji zredagowanej przez cyganologa Jerzego Ficowskiego. Ich oryginalna forma nosi znamiona hybrydyczności językowej i kulturowej. Podobnie jak w przypadku języków kreolskich ta uznana przez tłumacza za nieliteracką cecha została zatuszowana w przekładzie. Heteroglotyczność Papuszy ilustruje specyfikę języków lokalnych i społeczności wielojęzycznych, dla których charakterystyczne jest zjawisko ciągłego przekładu i dialogu międzykulturowego.
Prophecies of Civilizational Collapse 2.0: Michel Houellebecq’s Submission
Authors: Thompson Ewa 
Published: January 2025

The paper interprets a fictional biography of a French university professor bored with life. He tries the usual medicines: sex and other physical pleasures, debates with peers, and monastery solitude. No remedy seems to work. He fails to pay attention to one of his student lovers who chose commitment to a set of beliefs in Israel over pointless existence in Paris. The novel ends with political power in France passing on to the Muslim Brotherhood. The expected changes in social life follow. The professor allows himself to be carried on by the wave of decisions and beliefs provided by others. The paper argues that, in contrast to Mikhail Bulgakov’s thesis that “cowardice is the greatest sin,” Michel Houellebecq suggests that indolence is the source of our failures.
On soluble groups in which commutators have prime power order
Authors: Figueiredo Mateus , Shumyatsky Pavel 
Published: January 2025

Abstract
The article deals with finite groups in which commutators have prime power order (CPPO-groups).
We show that if 𝐺 is a soluble CPPO-group, then the order of the commutator subgroup

G
′

G^{\prime}

is divisible by at most two primes.
This improves an earlier result saying that the order of the commutator subgroup

G
′

G^{\prime}

is divisible by at most three primes.
Reaction duration impact on morphological, optical, structural and photoelectrochemical properties of hydrothermally synthesized TiO2 nanorods
Authors: Adedokun Oluwaseun , Muraina Abeeb O. , Jubu Peverga R. , Obaseki Oluwatosin S. , Adedokun Omonike M. , Ooi Mahayatun D. J. , Yam Fong K. 
Published: January 2025

Abstract
This study involved the hydrothermal synthesis of vertically oriented TiO2 nanorods on FTO substrate. We examined the impact of reaction duration on morphological, optical, structural and photoelectrochemical properties. The formation of TiO2 nanorods was confirmed by the FESEM and AFM results. The formation of TiO2 tetragonal crystal structure with the rutile phase was shown by XRD spectra. The average absorbance of the samples falls as the reaction duration increases, according to UV–vis spectroscopy analysis. According to PEC experiments, each sample demonstrated a strong photocurrent density and good light response in various lighting situations. The highest possible photocurrent density of 91.8 μA/cm2 at 1.2 V vs Ag/AgCl was recorded from TiO2 film with the reaction duration of 5 h (T@5 h). The quick separation and transfer of photogenerated charge carriers was demonstrated, and this result was confirmed by EIS data.
Disgust in early Islamic thought
Authors: Razzaque Arafat A 
Published: January 2025

The relationship between morality and disgust has been a matter of considerable interest and debate in modern scholarship, while its salience in premodern religious history still deserves more attention. This article focuses on the role of disgust in medieval Muslim thought, identifying relevant notions in classical Arabic and examining their usage in traditionist sources from the first few centuries of Islam (seventh to tenth centuries ce). Hadith narratives illustrate the concept of taqadhdhur or revulsion to a disgusting object, especially in the context of food. Well-known accounts of the Prophet Muhammad’s aversion to an Arab custom of eating lizards raised questions about the normative implications of his disgust, which medieval jurists sought to resolve through interpretive debates on the category of khaba'ith (disgusting things) in dietary law. In contrast to the circumstantial role of disgust in law, appeals to disgust served as a rhetorical strategy for moral persuasion against sin in the literature of hadith, Qur'anic exegesis, and traditions associated with renunciant piety (zuhd). A paradigmatic case is the invocation of a particular motif, the rotting corpse (jifa), which is considered to be a core elicitor of disgust and was frequently used in early Islamic sources as a trope for the vice of gossip or backbiting (ghiba). The metaphor was elaborated through traditions centered on the sensory dimensions of disgust as a bodily phenomenon. Stories of pious Muslims suggest the affective power of such traditions to inculcate revulsion toward sin. I argue that early Muslim pietists regarded disgust as a didactic instrument and a morally productive emotion.
Tulajdonképpeni jelentésükben (is) szinonim igék jelentéseinek összefüggései a felcserélhetőség és a szinonímia vonatkozásában
Authors: Hrenek Éva 
Published: January 2025

Esettanulmányomban három ige, a szúr, a bök és a döf jelentéseit elemezve az igei szinonímia azon típusával foglalkozom, amelyben az egy szinonimakörbe tartozó igék tulajdonképpeni jelentésükben is közel állnak egymáshoz. A valós nyelvhasználatból származó (korpusz)adatokat vizsgáló kutatásom egyrészt a szerves nyelvelmélet komponenses szemantikájára épül, amely a metaforizációs folyamatokban is döntő szerepet tulajdonít a jelentésmozzanatoknak (pl. Zsilka 1978), másrészt a rendelkezésre álló korpuszadatokon gyakorisági vizsgálatokat is végzek, összekapcsolva egymással a kvalitatív jelentéselemzések eredményeit és a gyakorisági adatokat. Az eredmények értelmezése során felhasználom a funkcionális kognitív nyelvészet (pl. Dancygier (szerk.) 2017, Tolcsvai Nagy (szerk.) 2017) releváns alapvetéseit is. Az itt bemutatott kutatás fő célkitűzése a felcserélhetőség és a(z igei) szinonímia közötti kapcsolat jobb megismerése, valamint annak feltérképezése, hogy hogyan integrálhatók a gyakorisági adatok a dolgozatban felvázolt, alapvetően kvalitatív elemzéseken alapuló megközelítésbe.
Advancements in nanotechnology for glaucoma detection and treatment: A focus on biosensors, IOP monitoring, and nano-drug delivery systems
Authors: Bhagwat Ajay , Badhe Nutan , Maniyar Sana , Kadale Priyanka , Kale Ruchira , Doke Rohit Ramesh 
Published: January 2025

Biosensors are essential tools designed to monitor physiologically significant data for diverse applications, including environmental pollution detection, food safety, medication research, and disease diagnosis. The integration of microfluidics, nanotechnology, and advanced electronics has significantly advanced the development of wearable and implantable biosensors for managing chronic diseases such as cancer, diabetes, and glaucoma. Among these, glaucoma remains a leading cause of visual impairment, predominantly driven by elevated intraocular pressure (IOP), with limited treatment effectiveness due to challenges like suboptimal drug bioavailability and therapeutic inefficiency. Despite advances, unmet needs in early diagnosis and sustained management persist, demanding innovative solutions.Recent advancements in nanotechnology offer transformative potential, addressing these challenges by enhancing both the detection and treatment of ocular diseases. This review explores cutting-edge developments in nano-drug delivery systems and continuous IOP monitoring technologies. Particular emphasis is placed on nanoparticle and nanofiber-based biosensors and contact lenses, which represent a promising leap forward in improving therapeutic precision and patient outcomes in glaucoma care. The manuscript uniquely contributes by synthesizing these advancements and highlighting their potential to bridge existing gaps in glaucoma management.
A clinicopathological study of eyelid tumors at a tertiary care hospital in South India
Authors: H A Chaitra , Karakuchi Bhagyalakshmi , Jiragyal Poonam A 
Published: January 2025

Eyelid tumors are common in people of all age groups representing more than 90% of ophthalmic tumors. Usually majority of these cases are either inflammatory or non-malignant tumors, however many malignancies can mimic a host of benign neoplasms and need differentiation before definitive therapy is started.To analyze clinical presentation, types of eyelid tumors, its histopathological correlation and management.A prospective study was conducted on patients presenting with eyelid tumors to our tertiary care hospital for duration of 2 years. Patients with eyelid tumors who fulfilled the inclusion criteria were diagnosed clinically and treated accordingly and all tumors were subjected to histopathological examination. The cases were analyzed for their age and sex distribution, incidence of malignant and benign tumors, tumor location and type. : In our study involving 50 patients, 29 were females and 21 were males, 47 cases were benign and 3 were malignant. Mean age of presentation of benign tumors was 44.81 years and malignant tumors was 67.25 years. Upper lid involvement was seen in 38 cases and lower lid in 12 cases. Intradermal nevus and epidermal cyst were the most common benign lesions and Sebaceous gland carcinoma was the most common malignant lesion. : Histopathological examination of all excised eyelid tumors is essential, as they may be malignant and require definitive treatment for better long-term management of the patient.
Impact of Gibberellic Acid and Growth Stimulants on Productivity Metrics of Kagzi Acid Lime (Citrus aurantifolia Swingle)
Authors: Bairwa Sunil Kumar , Bhatnagar Prerak , Singh Jitendra , Aravindakshan Kavita , Chopra Rahul , Chhipa Hemraj 
Published: January 2025

Background: Acid lime is a nutrient-intensive crop and it needs sufficient mineral nutrition for healthy growth and development and there was a need to study the effect of GA3 and growth-promoting chemicals as a nutrient source for acid lime cv. Kagzi trees. The reason to undertake this research was based on the impact of GA3 and growth-inducing chemicals on better nutrient supplementation, quick nutrient intact, better photosynthates translocation and carbohydrates mobilization and its effect on production parameters in acid lime cv. Kagzi trees. Methods: A field trial was carried out at the Fruit Instructional Farm, Department of Fruit Science, College of Horticulture and Forestry, Jhalawar between June 2023 and December 2023 in a 15-year-old established orchard of acid lime cv. Kagzi. The trial was set up following a randomized block design with three replications. It involved the application of nine different treatments through foliar spraying, which included GA3 and various growth-promoting chemicals such as KNO3, thiourea and salicylic acid. Result: According to the findings of the current study, the foliar application of T4 treatment (GA3 @ 100 mg/l + KNO3 @ 2%) proved to be more successful in enhancing the production parameters of acid lime cv. Kagzi. The application of T4 treatment comprising GA3 @ 100 mg/l + KNO3 @ 2 % resulted in the shortest time to initiate flowering (40.05 days), the briefest flowering period (53.79 days), the highest number of flowers per shoot (144.66), the greatest fruit set percentage (69.08%) and the highest fruit retention percentage (47.37%). The foliar application of treatment T4 (GA3 @ 100 mg/l + KNO3 @ 2%) proved to be the most successful in increasing the fruit count per tree (448.00), fruit weight (70.00 g) and yield (31.35 kg/tree) in Kagzi acid lime trees.
Perbandingan Kadar Hemoglobin dan Hematokrit pada Early Onset dan Late Onset Preeclampsia di RSUD Dr. Moewardi Surakarta
Authors: Annisa Rizki Savitri  , Wisnu Prabowo  , Eric Edwin Yuliantara  
Published: January 2025

Pendahuluan: Preeklampsia merupakan salah satu penyebab tingginya angka kematian ibu, terutama di negara berkembang. Pemeriksaan hematokrit dan hemoglobin adalah salah satu pemeriksaan yang mudah dilakukan di hampir semua fasilitas kesehatan. Banyak penelitian menunjukkan bahwa early onset preeclampsia (EO-PE) dikaitkan dengan kondisi kehamilan yang lebih buruk dibandingkan late onset preeclampsia (LO-PE). Penelitian ini bertujuan untuk mengetahui perbandingan hematokrit dan hemoglobin pada early onset dan late onset preeclampsia sehingga diharapkan dapat menjadi sarana deteksi dini sederhana dan mudah dilakukan, serta berpotensi untuk dikembangkan.
Metode: Penelitian ini merupakan studi cross sectional dengan metode analisis uji T Independen dan regresi logistik. Sampel diambil dari data sekunder berupa rekam medis di RSUD Dr. Moewardi sejak Januari 2021 — Mei 2023.
Hasil: Sampel yang memenuhi kriteria didapatkan 50 wanita dengan EO-PE dan 50 wanita dengan LO-PE. Hasil penelitian ini didapatkan nilai rerata hemoglobin pada EO-PE yaitu 12,852g/dL dan pada LO-PE 11,030 g/dL, dengan perbandingan rerata yang signifikan (p-value 0,000). Sedangkan pada hematokrit didapatkan nilai rerata pada EO-PE yaitu 37,138% dan pada LO-PE didapatkan mean 32,148% dan hasil perbandingan reratanya signifikan (p-value 0,000). Perbandingan hubungan hemoglobin dan hematokrit terhadap onset preeklampsia didapatkan hemoglobin (OR 2,003) lebih berhubungan dengan EO-PE dibandingkan hematokrit (OR 1,219).
Kesimpulan: Mean hemoglobin serta hematokrit pada early onset preeclampsia lebih tinggi secara signifikan dibandingkan dengan late onset preeclampsia. Hemoglobin lebih berhubungan dengan early onset preeclampsia dibandingkan hematokrit.
MIP-3α-antigen fusion DNA vaccine enhances sex differences in tuberculosis model and alters dendritic cell activity early post vaccination
Authors: Gordy James T. , Bates Rowan E. , Glass Elizabeth , Meza Jacob , Li Yangchen , Schill Courtney , Taylor Alannah D. , Wang Tianyin , Chen Fengyixin , Plunkett Khaleel , Karanika Styliani , Karakousis Petros C. , Markham Richard B. 
Published: January 2025

Abstract

Background
Tuberculosis (TB) remains a major cause of global morbidity and mortality. Efforts to control TB are hampered by the lengthy and cumbersome treatment required to eradicate the infection. Bacterial persistence during exposure to bactericidal antibiotics is at least partially mediated by the bacterial stringent response enzyme, RelMtb. A therapeutic DNA vaccine targeting RelMtb has been shown to increase the efficacy of antitubercular drugs, and fusing macrophage-inflammatory protein 3α (MIP-3α), which interacts with CCR6 on immature dendritic cells (iDCs), to RelMtb further increases the vaccine’s therapeutic efficacy. A secondary analysis of these prior studies elucidated prominent sex-based differences in vaccine therapeutic efficacy, with female mice showing improved microbial outcomes compared to males as a result of the Rel and MIP-3α-Rel vaccine constructs, with a greater sex-associated difference in the MIP-3α-Rel group. In the current study, we addressed the hypothesis that these sex-related differences are due to differential DC activation/function soon after vaccination.
Methods
A EαGFP reporter vaccine model was used to track vaccine antigen presentation by an antibody Y-Ae which binds the Eα peptide tag in complex with I-Ab MHC-II molecules.
Results
MIP-3α-EαGFP groups had more DCs presenting vaccine antigen infiltrating from the periphery, with more abundant Langerhans cells in males and greater CD8 + CD103 + cross-presenting dermal DCs in females. This model also shows there is greater DC activation, as measured by CD80 and MHC II MFI, by MIP-3α compared to EαGFP alone, especially in female mice.
Conclusions
Our findings are consistent with the sex- and MIP-3α-related differences seen in the therapeutic model and supports the hypothesis that in both sexes MIP-3α enhances vaccine uptake and cell activation by peripheral iDCs. Additionally, Female mice showed greater levels of antigen presentation, especially in DCs able to cross-present antigen, explaining why they had the best outcomes. Further studies are required to understand underlying mechanisms and to link APC results directly to T-cell responses.
Where and when will the next record-breaking precipitation disaster occur?
Authors: de Vries Iris , Schillinger Maybritt , Fischer Erich , Sippel Sebastian , Knutti Reto 
Published: January 2025

Abstract

Climate change increases the frequency and intensity of extreme precipitation over most of the global land, and flood impacts associated with extreme precipitation lead to major damage to society, economy, and ecosystems. Record-high precipitation events are particularly relevant for impacts since they are by definition more severe than any historical event, and can thus lead to unforeseeable damage. Both the probability of breaking local records in our real climate as well as the preparedness of local society for record-high events is dependent on the observed extreme event history.

Here, we estimate local extreme precipitation disaster potential, the potential for record-high precipitation to occur and cause a high-impact disaster, conditional on historical observations. Based on two observational datasets and reanalysis, we find that natural variability strongly shapes the global pattern of future conditional record breaking probabilities, highlighting that any region can be subject to high disaster potential if its current record value happens to be low. Climate change modifies this pattern in a non-linear manner: while climate change according to the SSP2-4.5 scenario increases the average probability of breaking a record by 2050 about 1.4 times, high (more rare) current records are much more sensitive to climate change, featuring an up to 2.5 times increase in record breaking probabilities by 2050. In other words: regions with low current records are most at risk, but for regions with high current records climate change increases the risk at the highest rate.

Disaster potential is further increased by low preparedness related to disaster memory: the longer ago the last record-breaking event, the more likely that local society is unaware of and underprepared for the risk. High disaster potential regions are dispersed globally but hotspots appear in Australia and in particularly vulnerable regions in the tropics and South-East Asia.
Vulnerability and exposure in many of these regions is high due to poverty and rapid urbanisation, associated with adaptation gaps, resulting in a major, imminent threat.
Structural Features of Pathogenic Aggregates Correlate with Cell Pathology in Differentiated Cells
Authors: Raz Vered , Mallon Sander , Bos Erik , Sheikhhassani Vahid , Shademan Milad , Voortman Lennard , Mashaghi Alireza , Sharp Thom 
Published: January 2025

Abstract

The accumulation of intracellular protein aggregates is a hallmark of aging. In hereditary adult-onset neuromuscular diseases (NMDs), these aggregates are not only characteristic but also pathogenic, marking age-related neuromuscular disorders. The transition from age-associated non-pathogenic aggregates to disease-driving pathogenic aggregates remains poorly understood. Poly(A) binding protein nuclear 1 (PABPN1) forms non-pathogenic nuclear aggregates in post-mitotic aged cells. However, a short trinucleotide expansion in PABPN1 leads to muscle dysfunction in Oculopharyngeal Muscular Dystrophy (OPMD), where insoluble nuclear aggregates in skeletal muscle become a defining disease feature. Combining an array of advanced imaging modalities, we examined the morphological differences between nuclear aggregates formed by non-pathogenic and pathogenic PABPN1 variants. Through micro- to nanoscale analyses, we identified key structural differences in the aggregation propensity of these variants in both differentiated and undifferentiated muscle cells and linked these differences to mRNA cellular dysfunctions. Our findings provide new insights into the structural distinctions between pathogenic and non-pathogenic aggregates and their implications for cellular dysfunction in neuromuscular diseases.