bluuebunny/crossref_metadata_2025_split huggingface dataset:
Placental lncRNA Expression in Monochorionic Twins with Selective Intrauterine Growth Restriction
Authors: Su Xiaohan , Hu Yucheng , Li Chunxiao , Li Shuyuan , Zhang Yong , Wang Yanlin 
Published: March 2023

Abstract
Background
Selective intrauterine growth restriction (sIUGR) affects about 10–15% of monochorionic (MC) twin pregnancies. The lncRNA profiles of placenta complicated with sIUGR are unknown. In the present study, the sIUGR-associated placental lncRNA expression was investigated using sequencing and confirmatory reverse transcriptase-quantitative polymerase chain reaction studies.
Methods
Placenta samples around the insertion region of the umbilical cord were collected from monochorionic twins complicated with (n = 9) or without sIUGR (control, n = 9). lncRNA and mRNA profile analysis was performed using transcriptome sequencing and validated by RT-PCR.
Results
A total of 30 lncRNAs were differentially expressed (17 up-regulated and 13 down-regulated) in the placenta of sIUGR cases compared with control cases. The differentially expressed lncRNAs were mainly involved in the mitogen-activated protein kinase signaling pathway (MAPK signaling pathway), ubiquitin proteasome pathway and angiogenesis pathway, which might be associated with the pathogenesis of sIUGR.
Conclusions
To the best of our knowledge, the findings of the current study have provided the first lncRNA profiles and the possible lncRNA regulatory networks of placental tissues complicated with sIUGR.
Treatment of coal fly ash and its environmentally friendly use in rubber and plastic industry
Authors: Hussain Zawar , Al-Zaqril Nabil , Boshaala Ahmed , Ayaz Tehreem , Khan Amir Zeb 
Published: March 2023

Abstract
Coal power plants are the major provider of electricity, but these power plants are also producing waste in the form of coal fly ash (CFA). However, it can cause high risk of environmental pollution and pulmonary diseases in humans. Plastic waste is also a problematic waste for many countries in terms of its reuse and recycling. Therefore, this study aims to reuse the waste product (CFA) of coal power plants in rubber conveyor belt instead of calcium carbonate or talcum powder and in recycling of plastic propylene as bonding filler material instead of barium sulfate to increase the durability of plastic products and reduce cost, CFA waste and plastic waste. For this purpose, CFA was treated by different pulverization techniques for the production of conveyor belts. The study found that the most favorable technique was shear based pulverization technique. Application of CFA with rubber was compared with two different chemicals (calcium carbonate and talcum powder) and found that the elongation at break of conveyor belt was 35% increased and abrasion volume was 64% reduced by using treated CFA. Furthermore, CFA was used in molten mass of plastic instead of barium sulfate and the results showed that the use of CFA has improved the dimensional stability of plastic material reducing the cost per ton by 2410 CNY. The study concluded that the performance was increased by applying CFA with a reduction in price as compared to other chemicals.
Assessment of water demand and potential water sources to face future water scarcity of hilly regions
Authors: V. Kannan , Priya P. Raja , K. Tharkeshwari , Mazumder Bineta , Gayatri P. , Neha Jackline 
Published: March 2023

Abstract
In this work, an attempt is made to predict the future water demand of a hilly region. The study area is selected based on the population and the water demand. For this work, Namunaghar and Wandoor Panchayats of Andaman and Nicobar Islands are selected. Initially, preliminary studies such as the current population and future growth and their water demand were analyzed. Also, using a geographical information system (GIS), the study area is located to identify the surface and groundwater sources. From the GIS data, a detailed map is prepared to conduct the physical verification and collect the water quality measurement. From the population forecast, it was identified that 435,000 and 480,300 l of water are required to meet the water demand in the year 2031 Namunaghar and Wander Panchayat, respectively. It also assessed the GIS data and found out potential water sources of 157 (67 wells, 58 ponds, and other minor sources) and 485 (215 wells, 229 ponds, and other minor sources) at Namunaghar and Wandoor Panchayats, respectively. Finally, all the potential water sources were checked for quality for drinking purposes.
Mechanistic action of pesticides on pests and their consequent effect on fishes and human health with remediation strategies
Authors: Singh Anita , Mahajan Monika , Kothari Richa , Singh Navin Kumar , Singh Rajeev Pratap 
Published: March 2023

Abstract
Population detonation and inflated demand for agricultural products have resulted in the rampant use of pesticides in recent years. These pesticides are used to reduce the number of pesticides by different mechanisms. They have been utilized in agriculture to expand agrarian profit, crop yield, quality, and storage life. The incessant and extensive use of resistant pesticides has contaminated the water bodies, fields, crops, and aquatic biota as well as poses a threat to human health. As a result, stringent regulations and limits are established to monitor the pesticide matrix. The current review focuses on pesticide contamination in the food chain, particularly from the aquatic bodies to fishes and humans. It also discusses strict regulations and limits including maximum residual limits for food items, acceptable daily intake, theoretical maximum daily intake, and estimated carcinogenicity/non-carcinogenicity for fishes and human health risks. In addition to conferring the negative effects of pesticides, this article discusses cost-effective remediation techniques such as phytoremediation, adsorption, the Fenton oxidation method, microalgal/high-rate algal ponds, and nanotechnology with the comparison of their remediation cost.
Impact of snow distribution modelling for runoff predictions
Authors: Clemenzi Ilaria , Gustafsson David , Marchand Wolf-Dietrich , Norell Björn , Zhang Jie , Pettersson Rickard , Allan Pohjola Veijo 
Published: March 2023

AbstractSnow in the mountains is essential for the water cycle in cold regions. The complexity of the snow processes in such an environment makes it challenging for accurate snow and runoff predictions. Various snow modelling approaches have been developed, especially to improve snow predictions. In this study, we compared the ability to improve runoff predictions in the Överuman Catchment, Northern Sweden, using different parametric representations of snow distribution. They included a temperature-based method, a snowfall distribution (SF) function based on wind characteristics and a snow depletion curve (DC). Moreover, we assessed the benefit of using distributed snow observations in addition to runoff in the hydrological model calibration. We found that models with the SF function based on wind characteristics better predicted the snow water equivalent (SWE) close to the peak of accumulation than models without this function. For runoff predictions, models with the SF function and the DC showed good performances (median Nash–Sutcliffe efficiency equal to 0.71). Despite differences among the calibration criteria for the different snow process representations, snow observations in model calibration added values for SWE and runoff predictions.
Prediction of groundwater level fluctuations under climate change based on machine learning algorithms in the Mashhad aquifer, Iran
Authors: Panahi Ghasem , Hassanzadeh Eskafi Mahya , Faridhosseini Alireza , Khodashenas Saeed Reza , Rohani Abbas 
Published: March 2023

AbstractThe purpose of this study is the projection of climate change's impact on the Groundwater Level (GWL) fluctuations in the Mashhad aquifer during the future period (2022–2064). In the first step, the climatic variables using ACCESS-CM2 model under the Shared Socio-economic Pathways (SSPs) 5–8.5 scenario were extracted. In the second step, different machine learning algorithms, including Multilayer Perceptron Neural Network (MLP), Adaptive Neuro-fuzzy Inference System Neutral Network (ANFIS), Radial Basis Function Neural Network (RBF), and Support Vector Machine (SVM) were employed for the GWL fluctuations time series prediction under climate change in the future. Our results point out that temperatures and evaporation will increase in the autumn season, and precipitation will decrease by 26%. The amount of evaporation will increase in the winter due to an increase in temperature and a decrease in precipitation. The results showed that the RBFNN model had an excellent performance in predicting GWL compared to other models due to the highest value of R² (R² = 0.99) and the lowest value of RMSE, which were 0.05 and 0.06 meters in training and testing steps, respectively. Based on the result of the RBFNN model, the GWL will decrease by 6.60 meters under the SSP5-8.5 scenario.
Status quo and change characteristics of groundwater resources pollution in the Hami region based on sustainable development strategies
Authors: Wu Yan , Zhao Shajunyi 
Published: March 2023

AbstractWater shortage is a universal resource problem worldwide, especially in arid and semi-arid regions. The Hami Basin is one of the most water-scarce areas in China, with low average annual precipitation and high evaporation. In order to effectively monitor groundwater problems, this paper proposes a study on the status and change characteristics of groundwater resource pollution in the Hami area based on sustainable development strategies, aiming to study the changes in groundwater in the Hami area and propose corresponding measures to reduce pollution and save water resources. The method of this article is to introduce the groundwater quality evaluation method, analyze the environmental carrying capacity and then study the evolution process of the groundwater environment in the Hami area. The function of the method is to assess the ecological risk of groundwater and the risk of groundwater pollution, and to analyze the changes in the carrying capacity of the local environmental system. This paper uses groundwater detection experiments to detect the current status of groundwater resource pollution and the characteristics of groundwater changes in the Hami area, and establish a groundwater numerical model in the Hami area.
Spatial and temporal trends of polyhalogenated carbazoles in sediments of the Yangtze river: insights into the origin
Authors: Da Chunnian , Ji Peng , Huang Qinghui , Yu Jin , Wu Linjun , Ye Jinsong 
Published: March 2023

Abstract
Fifteen surface sediments and three sediment cores were sampled in the Yangtze River (YR) of China to study the composition and temporal distribution trends of 10 selected polyhalogenated carbazoles (PHCZs) and gained insight into their origin. The total concentrations of PHCZs in the surface sediments ranged from 1.58 to 5.45 ng g−1 dry weight (dw), with an average of 3.11 ng g−1 dw. The composition profiles of PHCZs in the surface sediments were dominated by 1,3,6,8-tetrabromocarbazole, 1,3,6-dibromocarbazole, and 3,6-dichlorocarbazole. The variation trends of PHCZs in the sediment cores showed an apparent peak concentration and subsequently a significant decreasing trend in recent years. A strong correlation existed between PHCZs and sediment physicochemical properties. Furthermore, human activities directly or indirectly affected PHCZ concentrations. The evaluation of the potential toxic effect suggested that the toxic equivalent of PHCZs was less than the safe sediment value.
Attitudes towards LGBTQ+ Inclusion in Canadian Figure Skating
Authors: Schnell Andrew , Godley Jenny , Bridel William 
Published: March 2023

Background:As part of an examination of the current climate regarding gender and sexual diversity in figure skating, this paper reports on a 2019 pilot study examining the attitudes of athletes, coaches, officials, and administrators at Skate Canada (the national figure skating organization).Objectives:To describe attitudes towards LGBTQ+ inclusion in figure skating; to assess whether attitudes vary by gender, sexual identity, or level of participation in skating; and to examine the impact of contact with LGBTQ+ people on attitudes towards inclusion.Methods:We conducted an online survey of 106 Skate Canada members in 2019, including attitudinal, demographic, and inter-group contact questions. We employed factor analysis to summarize the attitudinal questions, and multiple regression analyses to examine the effects of demographic and contact variables on attitudes.Results:Four main factors emerged, reflecting a continuum of passive to active support for diversity and inclusion in skating. Although all respondents’ attitudes toward LGBTQ+ inclusion in figure skating were mostly positive, athletes and coaches were significantly less likely to believe that skating is an inclusive environment than volunteers and officials. Additionally, those who identified as gender and/or sexually diverse scored significantly higher on the personal advocacy factor. In the multiple regression analyses, more frequent contact with LGBTQ+ individuals was associated with significant increases in both passive and active support for inclusion.Conclusion:Gender and sexually diverse respondents, and those with more frequent contact with LGBTQ+ individuals, demonstrated higher levels of both active and passive support for inclusion in Canadian figure skating. We recommend that sports organizations should conduct ongoing attitudinal surveys of their membership to monitor progress towards LGBTQ+ inclusion, and should remain attuned to the unique experiences of LGBTQ+ athletes and coaches.
Spatiotemporal Changes in Pulmonary Tuberculosis Incidence in a Low-Epidemic Area of China in 2005-2020: Retrospective Spatiotemporal Analysis
Authors: Zhang Qi , Ding Huan , Gao Song , Zhang Shipeng , Shen Shiya , Chen Xiaoyan , Xu Zhuping 
Published: March 2023

Background
In China, tuberculosis (TB) is still a major public health problem, and the incidence of TB has significant spatial heterogeneity.

Objective
This study aimed to investigate the temporal trends and spatial patterns of pulmonary tuberculosis (PTB) in a low-epidemic area of eastern China, Wuxi city, from 2005 to 2020.

Methods
The data of PTB cases from 2005 to 2020 were obtained from the Tuberculosis Information Management System. The joinpoint regression model was used to identify the changes in the secular temporal trend. Kernel density analysis and hot spot analysis were used to explore the spatial distribution characteristics and clusters of the PTB incidence rate.

Results
A total of 37,592 cases were registered during 2005-2020, with an average annual incidence rate of 34.6 per 100,000 population. The population older than 60 years had the highest incidence rate of 59.0 per 100,000 population. In the study period, the incidence rate decreased from 50.4 to 23.9 per 100,000 population, with an average annual percent change of –4.9% (95% CI –6.8% to –2.9%). The incidence rate of pathogen-positive patients increased during 2017-2020, with an annual percent change of 13.4% (95% CI 4.3%-23.2%). The TB cases were mainly concentrated in the city center, and the incidence of hot spots areas gradually changed from rural areas to urban areas during the study period.

Conclusions
The PTB incidence rate in Wuxi city has been declining rapidly with the effective implementation of strategies and projects. The populated urban centers will become key areas of TB prevention and control, especially in the older population.
Attitudes of Children, Adolescents, and Their Parents Toward Digital Health Interventions: Scoping Review
Authors: d'Halluin Arnaud , Costa Marie , Morgiève Margot , Sebbane Déborah 
Published: March 2023

Background
The prevalence of mental health problems in children and adolescents is high. As these problems can impact this population’s developmental trajectories, they constitute a public health concern. This situation is accentuated by the fact that children and adolescents infrequently seek help. Digital health interventions (DHIs) offer an opportunity to bridge the treatment gap between health care needs and patient engagement in care. Additional detailed research is needed to identify how children and adolescents can be empowered to access help through DHIs. In this context, an understanding of their attitudes toward digital health appears to be a necessary first step in facilitating the effective implementation of DHIs.

Objective
This study aimed to establish an inventory of children’s, adolescents’, and their parents’ attitudes toward DHIs.

Methods
A scoping review following PRISMA-ScR (Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews) recommendations was performed using the MEDLINE, Embase, and PsycINFO databases. This research was conducted using 3 key concepts: “child and adolescent mental health service users,” “digital health interventions,” and “attitudes.” Data extracted included the name of the publishing journal, the methodology used, the target population, the DHI studied, and the principal results.

Results
Of 1548 studies found, 30 (1.94%) were included in our analysis. Among these, 13 concerned satisfaction, 24 concerned preferences, 22 concerned the use of DHI, 11 concerned perception, and 10 concerned needs.

Conclusions
The results of this study provide a better understanding of the factors influencing children’s and adolescents’ attitudes toward digital health and DHIs. The continued growth of DHIs can help reduce barriers to mental health care. Future research on these interventions should investigate the needs of the targeted populations to increase their engagement in care.
Clitoral Therapy Device for Alleviating Sexual Dysfunction After Female Genital Mutilation: Randomized Controlled Trial
Authors: Sakr Hend Reda , Ahmed Yahia Ali , Kamel Reham Mohamed , Abdelhady Reem Hamdy , Elkalla Reham Alaa , Georgui Mina Atef , Abd El-khalek Wael Osama , El Ebrashy Mariam Hossam 
Published: March 2023

Background
Female genital mutilation is considered a crime but is still practiced today in Africa and the Middle East, despite all the laws that make this procedure illegal due to the long-term physical and psychological harm it causes to women. Millions of girls and women living today have undergone genital mutilation, which involves removing the external female genitalia either partially or totally, based on the belief that it restricts feminine sexuality, thereby “saving” a girl for marriage. For girls and women, the surgery offers no health advantages. Girls’ right to control critical decisions regarding their sexual and reproductive health is violated because genital mutilation is frequently done against their will and frequently without their consent, leading to lifelong psychic trauma in addition to sexual dysfunction and lack of satisfaction due to distortion of the genitalia that threatens marital stability.

Objective
To determine the effect of a clitoral therapy device on improving sexual domains in women suffering from sexual dysfunction after female genital mutilation.

Methods
This study examined 80 married women aged from 20 to 45 years who were referred from the gynecology outpatient clinic of the Faculty of Medicine, Suez University, for sexual dysfunction resulting from female genital mutilation. The women were divided into 2 equal groups: the study group received a clitoral therapy device and traditional psychosexual education and were closely followed for 3 months, while the control group received only traditional psychosexual education for 3 months. The Arabic version of the Female Sexual Function Index (FSFI) questionnaire was used to assess sexual outcomes pre- and posttreatment in the 2 groups.

Results
Our findings revealed a significant increase in the 6 domains of the FSFI pretreatment in both groups compared to posttreatment (P>.001), except the orgasm domain in the control group, which showed only a nonsignificant increase (P=.16).

Conclusions
Clitoral therapy devices may be an effective, safe, noninvasive rehabilitation method for sexual dysfunction following female genital mutilation.

Trial Registration
ClinicalTrials.gov NCT05039775; https://clinicaltrials.gov/ct2/show/NCT05039775
Analisis Kualitas Pelayanan Terhadap Kepuasan Wisatawan Prewedding di Pantai Melasti, Ungasan
Authors: Saputra I Gede Edi , Suprapto I Nyoman Arto , Sutiarso Moh. Agus 
Published: March 2023

Penelitian ini bertujuan untuk menganalisis kualitas pelayanan dan kepuasan wisatawan prewedding di Pantai Melasti Ungasan. Metode yang digunakan untuk mengumpulkan data adalah observasi, wawancara, penyebaran kuesioner dan studi dokumen. Penelitian ini menggunakan metode pendekatan mix methode, dimana memadukan pendekatan kualitatif dan kuantitatif. Untuk mengetahui kualitas pelayanan dan kepuasan wisatawan pada penelitian ini menggunakan analisis GAP, CSI (Costumer Satisfaction Index),dan IPA (Importance Performance Analysis). Berdasarkan hasil olah data melalui analisis CSI (Costumer Satisfaction Index), berada dalam katagori puas. Hal ini memberikan hasil wisatawan yang melakukan kegiatan prewedding merasa puas terhadap pelayanan yang diberikan oleh pengelola Pantai Melasti Ungasan pada saat ini.

This study intends to evaluate pre-wedding visitors' satisfaction with the level of service at Melasti Beach Ungasan. Observation, interviews, distribution of questionnaires, and document studies are the methods utilized to gather data. A mix method technique, which mixes qualitative and quantitative approaches, is used in this study. Using the analysis of GAP, CSI (Customer Satisfaction Index), and IPA, establish the level of service quality and tourist satisfaction in this study (Importance Performance Analysis). It falls under the satisfied category according to the outcomes of data processing through the study of the CSI (Customer Satisfaction Index). As a result, tourists who participate in pre-wedding activities are satisfied with the services offered at this time by the staff of Melasti Beach Ungasan.
Human Resource Management Practices and their potential relationship with Organizational Citizenship Behavior in educational institutes.
Authors: Khan Mubarak  Zaib , Niqab Muhammad , Hanson Janet 
Published: March 2023

The current trends in technology and globalization has encouraged Human resource management practices to adopt optimized strategies in dealing with challenges face by the educational institutions. In order to achieve the desired results and outcomes in educational institutions in a definite timeframe, valuable policies, capabilities and values need to be implemented. For creating a sustainable organizational environment, the organizational citizenship behavior (OCB) has been developed for supportive and cooperative interaction and relationship between the employer and employee by cooperating with each other for effective running of the schools. The current study is aimed to investigate the relationship between HRM practices and OCB in higher secondary schools in Dir Lower& Upper. This study is quantitative in nature and data was collected through closed ended questionnaire. The collected data was analyzed with person correlation techniques. It is found that HRM practices has a notable relationship with organizational citizenship behavior in higher secondary schools in Pakistan and results further speak out that performance appraisal has a high relationship with OCB while the rest of practices have low relationship with OCB. After discussion in light of available literature, recommendations has been framed for educational institutions and policy maker.