bluuebunny/crossref_metadata_2025_split huggingface dataset:
Graphene Quantum Dot‐PEI‐Cyclodextrin Nanocarrier for Simultaneous miR21a Delivery and Cell Imaging in Cancer Therapy
Authors: Heidari Mana , Salmanpour Mohsen , Najafi Haniyeh , Monajati Maryam , Rahiminezhad Zahra , Azarpira Negar , Sadat Abolmaali Samira , Tamaddon Ali Mohammad 
Published: May 2023

AbstractOver‐expression of miR21 plays an important role in several cancers by promoting cancer cell proliferation, migration, invasion, and metastasis. Here, we attempted to prepare a beta cyclodextrin‐polyethyleneimine‐graphene quantum dot (βCD‐PEI‐GQD) nanocarrier for cellular delivery of miR21a. For this purpose, tosylated‐βCD and GQD were conjugated to branched PEI. The product was characterized by FTIR, 1H‐NMR, and fluorescence spectroscopy. The morphology, particle size distribution, and ζ‐potential of miR21a were examined by TEM and DLS following overnight incubation with βCD‐PEI‐GQD in aqueous media. The miR21 silencing was measured by stem‐loop RT‐PCR in HepG2 human hepatoma cell line. Cellular uptake and cell toxicity assays were determined by fluorescence microscopy and Trypan blue staining method, respectively. The formation of miR21a/CD‐PEI‐GQD Nanoplex with a decreased average size of 114 nm and a ζ‐potential (+36.1 mV) lower than CD‐PEI‐GQD nanocarrier by adding miR21a was confirmed at optimum C/P ratio =8.7. RT‐PCR revealed that miR21a/βCD‐PEI‐GQD Nanoplex significantly downregulated miR21 expression levels effectively. Overall, miR21a delivery using CD‐PEI‐GQD is presented as a novel trackable nanocarrier for cancer therapy.
Solar‐CO2‐to‐Syngas Conversion Enabled by Precise Charge Transport Modulation
Authors: Mo Qiao‐Ling , Xu Shu‐Ran , Li Jia‐Le , Shi Xiao‐Qiang , Wu Yue , Xiao Fang‐Xing 
Published: May 2023

AbstractThe rational design of the directional charge transfer channel represents an important strategy to finely tune the charge migration and separation in photocatalytic CO2‐to‐fuel conversion. Despite the progress made in crafting high‐performance photocatalysts, developing elegant photosystems with precisely modulated interfacial charge transfer feature remains a grand challenge. Here, a facile one‐pot method is developed to achieve in situ self‐assembly of Pd nanocrystals (NYs) on the transition metal chalcogenide (TMC) substrate with the aid of a non‐conjugated insulating polymer, i.e., branched polyethylenimine (bPEI), for photoreduction of CO2 to syngas (CO/H2). The generic reducing capability of the abundant amine groups grafted on the molecular backbone of bPEI fosters the homogeneous growth of Pd NYs on the TMC framework. Intriguingly, the self‐assembled TMCs@bPEI@Pd heterostructure with bi‐directional spatial charge transport pathways exhibit significantly boosted photoactivity toward CO2‐to‐syngas conversion under visible light irradiation, wherein bPEI serves as an efficient hole transfer mediator, and simultaneously Pd NYs act as an electron‐withdrawing modulator for accelerating spatially vectorial charge separation. Furthermore, in‐depth understanding of the in situ formed intermediates during the CO2 photoreduction process are exquisitely probed. This work provides a quintessential paradigm for in situ construction of multi‐component heterojunction photosystem for solar‐to‐fuel energy conversion.
Tailoring Advanced N‐Defective and S‐Doped g‐C3N4 for Photocatalytic H2 Evolution
Authors: Wang Haitao , Jiang Jizhou , Yu Lianglang , Peng Jiahe , Song Zhou , Xiong Zhiguo , Li Neng , Xiang Kun , Zou Jing , Hsu Jyh‐Ping , Zhai Tianyou 
Published: May 2023

AbstractAlthough challenges remain, synergistic adjusting various microstructures and photo/electrochemical parameters of graphitic carbon nitride (g‐C3N4) in photocatalytic hydrogen evolution reaction (HER) are the keys to alleviating the energy crisis and environmental pollution. In this work, a novel nitrogen‐defective and sulfur‐doped g‐C3N4 (S‐g‐C3N4‐D) is designed elaborately. Subsequent physical and chemical characterization proved that the developed S‐g‐C3N4‐D not only displays well‐defined 2D lamellar morphology with a large porosity and a high specific surface area but also has an efficient light utilization and carriers‐separation and transfer. Moreover, the calculated optimal Gibbs free energy of adsorbed hydrogen (ΔGH*) for S‐g‐C3N4‐D at the S active sites is close to zero (≈0.24 eV) on the basis of first‐principle density functional theory (DFT). Accordingly, the developed S‐g‐C3N4‐D catalyst shows a high H2 evolution rate of 5651.5 µmol g−1 h−1. Both DFT calculations and experimental results reveal that a memorable defective g‐C3N4/S‐doped g‐C3N4 step‐scheme heterojunction is constructed between S‐doped domains and N‐defective domains in the structural configuration of S‐g‐C3N4‐D. This work exhibits a significant guidance for the design and fabrication of high‐efficiency photocatalysts.
Pressure‐Stabilized High‐Entropy (FeCoNiCuRu)S2 Sulfide Anode toward Simultaneously Fast and Durable Lithium/Sodium Ion Storage
Authors: Cheng Wenbo , Liu Jie , Hu Jun , Peng Wenfeng , Niu Guoliang , Li Junkai , Cheng Yong , Feng Xiaolei , Fang Leiming , Wang Ming‐Sheng , Redfern Simon A. T. , Tang Mingxue , Wang Gongkai , Gou Huiyang 
Published: May 2023

AbstractPressure‐stabilized high‐entropy sulfide (FeCoNiCuRu)S2 (HES) is proposed as an anode material for fast and long‐term stable lithium/sodium storage performance (over 85% retention after 15 000 cycles @10 A g−1). Its superior electrochemical performance is strongly related to the increased electrical conductivity and slow diffusion characteristics of entropy‐stabilized HES. The reversible conversion reaction mechanism, investigated by ex‐situ XRD, XPS, TEM, and NMR, further confirms the stability of the host matrix of HES after the completion of the whole conversion process. A practical demonstration of assembled lithium/sodium capacitors also confirms the high energy/power density and long‐term stability (retention of 92% over 15 000 cycles @5 A g−1) of this material. The findings point to a feasible high‐pressure route to realize new high‐entropy materials for optimized energy storage performance.
Dual Modification of Chayotextle Starch: Effect on Physicochemical, Functional, and Structural Properties
Authors: Isaac Martínez‐Trejo Gerardo , Miguel Anaya‐Esparza Luis , Vargas‐Torres Apolonio , Pablo Hernández‐Uribe Juan , Omar Viñas‐Bravo 
Published: May 2023

AbstractChemically modified starches are widely used as food additives to improve the appearance and physicochemical and biological properties of foods. The aim of this work is to chemically modify chayotextle (Sechium edule) starch by hydroxypropylation‐crosslinking, and evaluate the effects of degree of substitution (DS), swelling power (SP), solubility index (SI), pasting, thermal properties, and morphological and molecular characteristics. Polar‐Tex (modified maize starch) is used as control. The modified chayotextle starches (CHSs) exhibit a white color and DS values between 0.34% and 1.19% hydroxypropyl, dependening on propylene oxide concentration‐response. In addition, the SP and pasting properties are higher in modified CHS than in native CHS and Polar‐Tex. The SI and temperature of gelatinization of modified starches decrease compared to native sample. The morphology of native and modified CHS granules is spherical and oval. Fourier transform infrared and nuclear magnetic resonance studies confirm the structural modifications of CHS by hydroxypropylation‐crosslinking. Dual‐modified CHS can be potentially used as an additive in the food industry.
Glycemic Index and Amylose Content of 25 Japonica Rice Italian Cultivar
Authors: Rondanelli Mariangela , Haxhari Filip , Gasparri Clara , Barrile Gaetan Claude , Cavioni Alessandro , Guido Davide , Mansueto Francesca , Zese Marco , Mazzola Giuseppe , Moroni Alessia , Patelli Zaria , Peroni Gabriella , Pirola Martina , Tartara Alice , Cantaluppi Enrico , Campanini Luigi , Magnani Edoardo , Feccia Sergio , Perna Simone 
Published: May 2023

The glycemic index (GI) was developed to classify foods according to their ability to increase postprandial blood glucose. The literature reports that the GI of rice varieties ranges from 48 to 93. All studies evaluate Indica rice but none evaluates the GI of Japonica rice. Furthermore, no studies have been conducted to assess the relationship between amylose content and GI in Japonica rice. The aim of this study is to evaluate the GI and amylose content of 25 Japonica rice genotypes.This study is based on the standard method for GI determination according to the international standard ISO 26642; it includes two men and eight women (mean age 28.3 ± 3.7, Body Mass Index – BMI – 21.4 ± 2.6). Five rice genotypes show low GI (Selenio, Argo, Enr18215, Enr18328, Enr18433), 10 medium GI (Carnaroli, CL12, CL388, CRLB1, Elio, Enr18126, Iarim, S. Andrea, Tiberio, and Valente), and 10 high GI (Arborio, Lince, Duilio, Castelmochi, Padano, Puma, Baldo, CL18, CL35, CL71). A negative association is also observed between medium GI and amylose (r = −0.528). As the amylose content increases, the mean GI decreases.Five rice genotypes have a low GI and are therefore suitable for a healthy diet and for diabetics.
Monitoring food quality ‐ effect of curcumin in the development of polyethylene/thermoplastic starch based smart packaging
Authors: Hazer Seda , Aytac Ayse 
Published: May 2023

AbstractSmart packaging relies on the one‐to‐one interaction of food with its packaging or its environment to monitor food quality and safety. Colorimetric pH indicators (synthetic, natural) working in a smart food packaging system are particularly striking when used with fresh foodstuffs such as fish and meat that perish quickly and require real‐time freshness monitoring. In this study, curcumin (Cur) was used as a natural pH indicator to produce sustainable smart packaging material. Towards this objective, low‐density polyethylene (LDPE) and thermoplastic starch (TPS) blend‐based films containing Cur were prepared using a twin screw extrusion and hot‐pressing processes. Besides, two different compositions of LDPE/TPS mixture (50/50 and 70/30) were used as the matrix. Thermal, mechanical, morphological properties, an affinity for water, and color change properties of LDPE/TPS/Cur films were investigated. They showed a significant color change from yellow to brown at pH: 10 at the end of the seventh day, especially in the 50 LDPE/50 TPS mixture. 50 LDPE/50 TPS mixture with 7% curcumin content gave the highest tensile strength of 8.03 Mpa. When the same mixture was used to monitor chicken meat spoilage at 25°C, meat samples have shown color changes from light yellow to light brown due to the increased content of total volatile basic amines. As a result, it has been suggested that 50 LDPE/50 TPS mixture containing 7% Cur can be used as a smart packaging material.
Bio‐based compatibiliser enhancing the interface properties of CaCO3/recycled high‐density polyethylene composites
Authors: Ye Liangdong , Liu Hongbo , Li Dacheng , Wei Qiaoyan , Li Ziwei , Chen Dongming , Lu Shaorong 
Published: May 2023

AbstractThe fabrication of composites of two or more materials with different polarities requires the use of compatibilisers to improve interface properties. However, most compatibilisers used for industrial production are derived from the cracking products of petroleum, which is a limited resource susceptible to price fluctuations and pollutes the environment. In this study, a new compatibiliser derived from renewable plant‐oil‐based products, ESO–G–OA, was designed and synthesized using epoxy soybean oil, oleic acid, and glycerol. Scanning electron microscopy results showed that ESO–G–OA can effectively improve the dispersion of CaCO3 in a recycled high‐density polyethylene (reHDPE) matrix and reduce the interfacial gap between the two phases. The analysis of the mechanical properties showed that the ESO–G–OA‐modified composite has higher tensile and impact strength than unmodified samples. The ESO–G–OA modification improved the thermal stability and melt flow of the composite and reduced the energy consumption during processing. Moreover, the excellent compatibility of ESO–G–OA can improve the comprehensive properties of CaCO3/reHDPE composites, compensating for the performance reduction caused by the multiple processing steps necessary to obtain reHDPE. This confirmed that ESO–G–OA has promising application prospects in the production of composites requiring compatibilisers.
Improving Shop Floor-Near Production Management Through Data-Driven Insights
Authors: Schmitt R. H. , Kiesel R. , Buschmann D. , Cramer S. , Enslin C. , Fischer M. , Gries T. , Hopmann Ch. , Huebser L. , Janke T. , Kemmerling M. , Müller K. , Pelzer L. , Perau M. , Pourbafrani M. , Samsonov V. , Schlegel P. , Schopen M. , Schuh G. , Schulze T. , van der Aalst W. M. P. 
Published: May 2023

AbstractIn short-term production management of the Internet of Production (IoP) the vision of a Production Control Center is pursued, in which interlinked decision-support applications contribute to increasing decision-making quality and speed. The applications developed focus in particular on use cases near the shop floor with an emphasis on the key topics of production planning and control, production system configuration, and quality control loops.Within the Predictive Quality application, predictive models are used to derive insights from production data and subsequently improve the process- and product-related quality as well as enable automated Root Cause Analysis. The Parameter Prediction application uses invertible neural networks to predict process parameters that can be used to produce components with desired quality properties. The application Production Scheduling investigates the feasibility of applying reinforcement learning to common scheduling tasks in production and compares the performance of trained reinforcement learning agents to traditional methods. In the two applications Deviation Detection and Process Analyzer, the potentials of process mining in the context of production management are investigated. While the Deviation Detection application is designed to identify and mitigate performance and compliance deviations in production systems, the Process Analyzer concept enables the semi-automated detection of weaknesses in business and production processes utilizing event logs.With regard to the overall vision of the IoP, the developed applications contribute significantly to the intended interdisciplinary of production and information technology. For example, application-specific digital shadows are drafted based on the ongoing research work, and the applications are prototypically embedded in the IoP.
Moving Toward Net-Zero Emission Society: With Special Reference to the Recent Law and Policy Development in Some Selected Countries
Authors: Wu Hsing-Hao 
Published: May 2023

AbstractBy the Sixth IPPC Report issued in August 2021, man-made greenhouse gases emission is responsible for approximately 1.1 °C of warming between 1850 and 1900, and the global temperature is expected to reach or exceed 1.5 °C by 2041. The IPPC thus urges world leaders to adopt substantial and sustained reductions to reduce carbon dioxide (CO2) and other greenhouse gas emissions to stabilize global temperature by the next 20–30 years. In East Asia, the Former Prime Minister of Japan, Yoshihide Suga, declared that Japan will become carbon–neutral by 2050. The commitment has been further endorsed by his successor Prime Minister Kishida Fumio. Korea enacted the Carbon Neutrality Act, which requires the government to cut greenhouse gas emissions in 2030 by 35% or more from the 2018 levels in August 2021. In China, President Xi Jinping committed to achieving carbon neutrality by 2060 at the U.N. General Assembly in September 2020. In Taiwan, President Tsai Ing-wen announced on April 22, 2021, that Taiwan will achieve carbon neutrality by 2050. The road to achieving net-zero emissions is an ambitious but challenging goal for each significant GHGs emitter in the Asia–Pacific region. Each country has its own economic, social, and technological foundation and capabilities and thus requires different approaches to achieve the same goal. This chapter explores the recent global trends with particular references to EU, U.S., and Japan’s law and policy development aiming to achieve carbon neutrality goals by 2050.
Climate Impacts of Black Carbon and Methane Emissions in the Arctic and Current Frameworks for Prevention
Authors: Hataya Sakiko 
Published: May 2023

AbstractRapid environmental changes in the Arctic have brought increasing attention from the international community toward the region. Considering these circumstances, the Arctic Council (AC) provides an important vehicle for addressing Arctic issues. This paper first provides a basic overview on the Arctic Council and discusses recent organizational reforms. It also addresses how Japan is involved in the Arctic. Finally, this paper discusses what the Arctic Council, as well as other concerned countries, are doing to control black carbon emissions, which are a current problem in the Arctic.
Looking Ahead
Authors: Nordin Magdalena , Otterbeck Jonas 
Published: May 2023

AbstractIn this final chapter, we venture to give some advice on researching religion and migration, first on what we know and then on what is lacking. If some readers heed our call and caution, it will be a needed and important contribution to far-too-neglected areas in migration research. By ‘researchers’ we mean students, scholars, journalists and others who seriously try to produce knowledge about the situation. Please feel included.
Hypergraph Computation for Computer Vision
Authors: Dai Qionghai , Gao Yue 
Published: May 2023

AbstractIn this chapter, the applications of hypergraph computation in computer vision are introduced. Computer vision is one of the most widely used areas of hypergraph computation. The hypergraphs can be constructed by modeling the high-order relationship among inter- or intra-visual samples, and then computer vision tasks can be solved by hypergraph computation procedures. More specifically, four typical applications, including visual classification, 3D object retrieval, and tag-based social image retrieval, are provided, in which hypergraphs are used to model high-order relationship among samples and solve visual problems by hypergraph computation. For example, in social image retrieval, hypergraphs are used to model the high-order relationship among social images based on both visual and textual information, which is the high-order modeling of elements within samples.
Hypergraph Computation for Social Media Analysis
Authors: Dai Qionghai , Gao Yue 
Published: May 2023

AbstractSocial media, such as Twitter and Weibo, have grown rapidly over the past decade. Large numbers of active social media users produce a voluminous amount of data each day, from which important insights can be drawn. Several applications, such as recommender system and sentiment analysis, have been developed to help study the users’ intension and portrait. One common challenge faced by these social media applications is how to leverage the complex and multi-modal data on social networks and model the higher-order associations hidden in the data. Hypergraph computation has the huge potential to be used in such analysis. In this chapter, we introduce three typical applications of hypergraph computation, i.e., recommender system, sentiment analysis, and emotion recognition, from which hypergraph computation has shown great value on social media analysis.
Fourier Characterizations and Non-triviality of Gelfand–Shilov Spaces, with Applications to Toeplitz Operators
Authors: Petersson Albin 
Published: May 2023

AbstractWe find growth estimates on functions and their Fourier transforms in the one-parameter Gelfand–Shilov spaces$$S_s$$Ss,$$S^\sigma $$Sσ,$$\Sigma _s$$Σsand$$\Sigma ^\sigma $$Σσ. We obtain characterizations for these spaces and their duals in terms of estimates of short-time Fourier transforms. We determine conditions on the symbols of Toeplitz operators under which the operators are continuous on the one-parameter spaces. Lastly, it is determined that$$\Sigma _s^\sigma $$Σsσis nontrivial if and only if$$s+\sigma > 1$$s+σ>1.
Therapierelevante Antibiotikaresistenzen im One-Health-Kontext
Authors: Werner Guido , Abu Sin Muna , Bahrs Christina , Brogden Sandra , Feßler Andrea T. , Hagel Stefan , Kaspar Heike , Köck Robin , Kreienbrock Lothar , Krüger-Haker Henrike , Maechler Frederike , Noll Ines , Pletz Mathias W. , Tenhagen Bernd-Alois , Schwarz Stefan , Walther Birgit , Mielke Martin 
Published: May 2023

Zusammenfassung„One Health“ bezeichnet ein Konzept, das die Gesundheit von Menschen, Tieren und der Umwelt miteinander verbindet. In Deutschland gibt es umfangreiche Daten zur Antibiotikaresistenz (AMR) und multiresistenten Erregern (MRE) in der Human- und Veterinärmedizin sowie aus Untersuchungen in verschiedenen Umweltkompartimenten (Boden, Wasser, Abwasser). Die Erhebung erfolgt nach unterschiedlichen Vorgaben und Standards, was den Vergleich von Daten erschwert. Ein Fokus auf humantherapeutisch wichtige AMR und MRE ist hilfreich, um eine gewisse Orientierung vorzugeben. Die meisten Daten liegen sektorübergreifend zu Methicillin-resistenten Staphylococcus aureus und multiresistenten Enterobacterales wie Escherichia coli und Klebsiella pneumoniae vor. Hier sind die Trends der Resistenzen heterogen. Der Einsatz von Antibiotika führt zur Selektion von MRE, was gut dokumentiert ist. Erfolge bei der Minimierung des Antibiotikaeinsatzes konnten in zurückliegenden Jahren für einzelne Sektoren dargestellt und z. T. mit Erfolgen in der Eindämmung von AMR und MRE korreliert werden (Rückgang MRSA in der Humanmedizin). Auch sektorspezifische Maßnahmen zur Senkung der Last durch MRE und AMR sind notwendig, da Resistenzprobleme nicht generell eine Verknüpfung mit anderen Sektoren aufweisen. Carbapenemresistenzen sind vor allem bei pathogenen Erregern vom Menschen nachweisbar. Colistinresistenzen kommen in verschiedenen Sektoren vor, zeigen aber dort jeweils verschiedene Mechanismen. Resistenzen gegen Reservesubstanzen wie Linezolid sind in Deutschland selten, sie zeigen aber einen konkreten One-Health-Bezug. Bestrebungen zur Harmonisierung von Methoden, z. B. im Bereich der antimikrobiellen Empfindlichkeitstestung und genombasierten Erreger- und AMR-Surveillance, sind ein wichtiger erster Schritt zu einer Vergleichbarkeit der verschiedenen Datenerhebungen.
Rethinking “digital”: a genealogical enquiry into the meaning of digital and its impact on individuals and society
Authors: Capone Luca , Rocchi Marta , Bertolaso Marta 
Published: May 2023

AbstractIn the current social and technological scenario, the term digital is abundantly used with an apparently transparent and unambiguous meaning. This article aims to unveil the complexity of this concept, retracing its historical and cultural origin. This genealogical overview allows to understand the reason why an instrumental conception of digital media has prevailed, considering the digital as a mere tool to convey a message, as opposed to a constitutive conception. The constitutive conception places the digital phenomenon in the broader ground of media studies, and it considers digital technologies as an interface between the subject and the world. In this perspective, the media is not added to the experience of the person, but it shapes it from within on a cognitive, expressive and communicative level. The article makes use of two powerful examples to show the shortcomings of an instrumental conception of the digital, and to affirm the value of a constitutive conception for current media studies regarding digital interfaces.