bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cardiovascular response to anticipatory and reactionary postural perturbations in young adults
Authors: Siedlecki Patrick , Ivanova Tanya D. , Garland S. Jayne 
Published: July 2023

AbstractCardiovascular responses to postural perturbations have been reported, but whether the cardiovascular responses to external perturbations could be executed in anticipation of the perturbation is unknown. The purpose of this study was to determine the effect of anticipated and reactionary perturbations on heart rate (HR) and systolic blood pressure (SBP) responses in healthy young adults. A secondary aim was to determine whether perceived state anxiety scores were correlated with the change in HR response during postural perturbation. Twenty healthy young adults stood on a treadmill and experienced two perturbation conditions (anticipatory vs. reactionary), each with two intensity levels (Step vs. No Step). The HR and SBP were collected continuously. Two‐way repeated‐measures statistical non‐parametric mapping tests were used to compare HR and SBP responses to the perturbations over time (from −3 to +8 s). The results indicated that HR was significantly elevated in the higher intensity perturbations [Step vs. No Step, at 0.56–1.32 s (P < 0.0001) and 1.92–3.44 s (P < 0.0001) post‐perturbation], while there were no differences in HR between perturbation types (anticipatory vs. reactionary) or in SBP between perturbation types and intensity levels. The perceived state anxiety scores did not differ between perturbation types and intensity levels but were correlated with the change in HR post‐perturbation (P = 0.013). We suggest that reflexive mechanisms dominate cardiovascular regulation after anticipatory and reactionary perturbations. The data highlight the cardiovascular mechanism(s) associated with perturbations that should be considered when assessing postural stability in populations with poor balance performance.
Enriching research practices through knowledge about Indigenous research methodologies
Authors: Bolton Joanne , Remedios Louisa , Andrews Shawana 
Published: July 2023

Introduction
Learning about Indigenous research paradigms and methodologies offers insights and reflexive opportunities for those who seek to improve their research practice. This paper explores how research at the ‘interface’ can enrich scholarly inquiry across the academy. Whilst a single paper cannot do justice to the sophistication and nuance of Indigenous methodologies, as an authorship team of one Indigenous and two non-Indigenous academics, and through our established relationship and subsequent conversations, we present in this paper seven distilled methodological learnings that can enrich standard qualitative research practice. We predominantly explored the work of Indigenous scholars worldwide, and where relevant have drawn on non-Indigenous scholars where there may be ‘interface’ compatibilities. We also build off some of our previous work such as Andrews (2020a, 2020b), Andrews (2021) and Bolton and Andrews (2018).
It is very important to clearly state that we are not suggesting readers, particularly non-Indigenous readers, use this paper as a template for Indigenous research, or as a guide for conducting research with Indigenous peoples and communities. Rather, our intention is to share our personal learnings about Indigenous research with a view to bridging methodological understanding to achieve high quality qualitative research. Indigenous researchers have sought to navigate the interface between Indigenous and western research to generate new knowledge that reflects the interests, values and priorities of Indigenous peoples. The last twenty-five years has seen significant effort by Indigenous scholars across the globe to establish an Indigenous academic research agenda and pioneer change in research practices. The interface between Indigenous and western knowledge systems has much to offer research as a basis for the generation of new knowledge (Durie, 2004; Martin, 2008). It is at this interface, or intersection between two knowledges, that we make connections and offer our insights.
This paper is divided into four sections: Beginning, Middle, Reflective End and New Beginnings, a framework drawn from our work. Within these four sections are seven key methodological reflections under the sub-headings: Understanding place in research, Positionality, Worldviews in research, Privileging knowledges, Relational accountability, Storytelling as methodology and Circular research processes, and at each sub-heading is our key learnings. This is shown in Figure 1, noting the arrows grow in size as we approach ‘Beginning Again’ as a way of illustrating the enriching of knowledges and practices as the learning process loops iteratively.
Draft genomes of
Aspergillus nomiae
and
Aspergillus tamarii
isolates from human eye infections
Authors: Hatmaker E. Anne , Schmitz Jonathan E. , Rokas Antonis 
Published: July 2023

ABSTRACT

Fungal species within the genus
Aspergillus
are an important cause of human diseases, including aspergillosis and keratitis. We present draft genomes of
Aspergillus tamarii
and
A. nomiae
isolated from keratitis patients in a U.S. tertiary care hospital.
Racial and ethnic disparities in common inpatient safety outcomes in a children’s hospital cohort
Authors: Lyren Anne , Haines Elizabeth , Fanta Meghan , Gutzeit Michael , Staubach Katherine , Chundi Pavan , Ward Valerie , Srinivasan Lakshmi , Mackey Megan , Vonderhaar Michelle , Sisson Patricia , Sheffield-Bradshaw Ursula , Fryzlewicz Bonnie , Coffey Maitreya , Cowden John D 
Published: July 2023

BackgroundEmerging evidence has shown racial and ethnic disparities in rates of harm for hospitalised children. Previous work has also demonstrated how highly heterogeneous approaches to collection of race and ethnicity data pose challenges to population-level analyses. This work aims to both create an approach to aggregating safety data from multiple hospitals by race and ethnicity and apply the approach to the examination of potential disparities in high-frequency harm conditions.MethodsIn this cross-sectional, multicentre study, a cohort of hospitals from the Solutions for Patient Safety network with varying race and ethnicity data collection systems submitted validated central line-associated bloodstream infection (CLABSI) and unplanned extubation (UE) data stratified by patient race and ethnicity categories. Data were submitted using a crosswalk created by the study team that reconciled varying approaches to race and ethnicity data collection by participating hospitals. Harm rates for race and ethnicity categories were compared with reference values reflective of the cohort and broader children’s hospital population.ResultsRacial and ethnic disparities were identified in both harm types. Multiracial Hispanic, Combined Hispanic and Native Hawaiian or other Pacific Islander patients had CLABSI rates of 2.6–3.6 SD above reference values. For Black or African American patients, UE rates were 3.2–4.4 SD higher. Rates of both events in White patients were significantly lower than reference values.ConclusionsThe combination of harm data across hospitals with varying race and ethnicity collection systems was accomplished through iterative development of a race and ethnicity category framework. We identified racial and ethnic disparities in CLABSI and UE that can be addressed in future improvement work by identifying and modifying care delivery factors that contribute to safety disparities.
Renin–angiotensin system inhibition after surgical aortic valve replacement for aortic stenosis
Authors: Martinsson Andreas , Törngren Charlotta , Nielsen Susanne J , Pan Emily , Hansson Emma C , Taha Amar , Jeppsson Anders 
Published: July 2023

ObjectiveThe optimal medical therapy after surgical aortic valve replacement (SAVR) for aortic stenosis remains unknown. Renin–angiotensin system (RAS) inhibitors could potentially improve cardiac remodelling and clinical outcomes after SAVR.MethodsAll patients undergoing SAVR due to aortic stenosis in Sweden 2006–2020 and surviving 6 months after surgery were included. The primary outcome was major adverse cardiovascular events (MACEs; all-cause mortality, stroke or myocardial infarction). Secondary endpoints included the individual components of MACE and cardiovascular mortality. Time-updated adjusted Cox regression models were used to compare patients with and without RAS inhibitors. Subgroup analyses were performed, as well as a comparison between angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs).ResultsA total of 11 894 patients (mean age, 69.5 years, 40.4% women) were included. Median follow-up time was 5.4 (2.7–8.5) years. At baseline, 53.6% of patients were dispensed RAS inhibitors, this proportion remained stable during follow-up. RAS inhibition was associated with a lower risk of MACE (adjusted hazard ratio (aHR) 0.87 (95% CI 0.81 to 0.93), p<0.001), mainly driven by a lower risk of all-cause death (aHR 0.79 (0.73 to 0.86), p<0.001). The lower MACE risk was consistent in all subgroups except for those with mechanical prostheses (aHR 1.07 (0.84 to 1.37), p for interaction=0.040). Both treatment with ACE inhibitors (aHR 0.89 (95% CI 0.82 to 0.97)) and ARBs (0.87 (0.81 to 0.93)) were associated with lower risk of MACE.ConclusionThe results of this study suggest that medical therapy with an RAS inhibitor after SAVR is associated with a 13% lower risk of MACE and a 21% lower risk of all-cause death.
Symmetric deformed 2D/3D Hurwitz–Kontsevich model and affine Yangian of $${\mathfrak {gl}}(1)$$
Authors: Na Wang , Ke Wu 
Published: July 2023

AbstractSince the ($$\beta $$
β
-deformed) Hurwitz Kontsevich model corresponds to the special case of affine Yangian of $${\mathfrak {gl}}(1)$$

gl
(
1
)

. In this paper, we construct two general cases of the $$\beta $$
β
-deformed Hurwitz Kontsevich model. We find that the W-operators of these two models can be represented by the generators $$e_k,\ f_k,\psi _k$$

e
k

,

f
k

,

ψ
k

of the affine Yangian of $${\mathfrak {gl}}(1)$$

gl
(
1
)

, and the eigenstates (the symmetric functions $$Y_\lambda $$

Y
λ

and 3-Jack polynomials) can be obtained from the 3D Young diagram representation of affine Yangian of $${\mathfrak {gl}}(1)$$

gl
(
1
)

. Then we can see that the W-operators and eigenstates are symmetric about the permutations of coordinate axes.
UFO 2.0: the ‘Universal Feynman Output’ format
Authors: Darmé Luc , Degrande Céline , Duhr Claude , Fuks Benjamin , Goodsell Mark , Heinrich Gudrun , Hirschi Valentin , Höche Stefan , Höfer Marius , Isaacson Joshua , Mattelaer Olivier , Ohl Thorsten , Pagani Davide , Reuter Jürgen , Richardson Peter , Schumann Steffen , Shao Hua-Sheng , Siegert Frank , Zaro Marco 
Published: July 2023

AbstractWe present an update of the Universal FeynRules Output model format, commonly known as the UFO format, that is used by several automated matrix-element generators and high-energy physics software. We detail different features that have been proposed as extensions of the initial format during the last ten years, and collect them in the current second version of the model format that we coin the Universal Feynman Output format. Following the initial philosophy of the UFO, they consist of flexible and modular additions to address particle decays, custom propagators, form factors, the renormalisation group running of parameters and masses, and higher-order quantum corrections.
Traversable Morris–Thorne–Buchdahl wormholes in quadratic gravity
Authors: Nguyen Hoang Ky , Azreg-Aïnou Mustapha 
Published: July 2023

AbstractThe special Buchdahl-inspired metric obtained in a recent paper [Phys. Rev. D 107, 104008 (2023)] describes asymptotically flat spacetimes in pure $$\mathcal {R}^{2}$$

R

2

gravity. The metric depends on a new (Buchdahl) parameter $$\tilde{k}$$

k
~

of higher-derivative characteristic, and recovers the Schwarzschild metric when $$\tilde{k}=0$$

k
~

=
0

. It is shown that the special Buchdahl-inspired metric supports a two-way traversable Morris–Thorne wormhole for $$\tilde{k}\in (-1,0)$$

k
~

∈

(
-
1
,
0
)

in which case the Weak Energy Condition is formally violated, a naked singularity for $$\tilde{k}\in (-\infty ,-1)\cup (0,+\infty )$$

k
~

∈

(
-
∞
,
-
1
)

∪

(
0
,
+
∞
)

, and a non-Schwarzschild structure for $$\tilde{k}=-1$$

k
~

=
-
1

.
Data processing and visualization tool for atomic and molecular data for collisional radiative models
Authors: Cianfrani Francesco , Borodin Dmitry V. , Küppers Bettina 
Published: July 2023

Abstract
The Monte Carlo kinetic code EIRENE (Sect. 2) is used for simulating the behavior of neutral species in the edge of tokamak plasma and coupled with fluid plasma codes for a self-consistent description to be compared with measured experimental conditions. The data and visualization toolbox HYDKIN (Sect. 3) has been developed as a pre-processing tool for validation of those atomic and molecular (A &M) data used in EIRENE simulations, such as cross sections and reaction rates for plasma-neutral and neutral-neutral collisions. The restructuring that is being performed to increase HYDKIN readability and usability is here presented (Sect. 4).

Graphic Abstract
Cancer Epidemiology in the Northeastern United States (2013–2017)
Authors: Rees Judy R. , Weiss Julie E. , Gunn Christine M. , Carlos Heather A. , Dragnev Nathalie C. , Supattapone Emma Y. , Tosteson Anna N.A. , Kraft Sally A. , Vahdat Linda T. , Peacock Janet L. 
Published: July 2023

We tested the hypotheses that adult cancer incidence and mortality in the Northeast region and in Northern New England (NNE) were different than the rest of the United States, and described other related cancer metrics and risk factor prevalence. Using national, publicly available cancer registry data, we compared cancer incidence and mortality in the Northeast region with the United States and NNE with the United States overall and by race/ethnicity, using age-standardized cancer incidence and rate ratios (RR). Compared with the United States, age-adjusted cancer incidence in adults of all races combined was higher in the Northeast (RR, 1.07; 95% confidence interval [CI] 1.07–1.08) and in NNE (RR 1.06; CI 1.05–1.07). However compared with the United States, mortality was lower in the Northeast (RR, 0.98; CI 0.98–0.98) but higher in NNE (RR, 1.05; CI 1.03–1.06). Mortality in NNE was higher than the United States for cancers of the brain (RR, 1.16; CI 1.07–1.26), uterus (RR, 1.32; CI 1.14–1.52), esophagus (RR, 1.36; CI 1.26–1.47), lung (RR, 1.12; CI 1.09–1.15), bladder (RR, 1.23; CI 1.14–1.33), and melanoma (RR, 1.13; CI 1.01–1.27). Significantly higher overall cancer incidence was seen in the Northeast than the United States in all race/ethnicity subgroups except Native American/Alaska Natives (RR, 0.68; CI 0.64–0.72).
In conclusion, NNE has higher cancer incidence and mortality than the United States, a pattern that contrasts with the Northeast region, which has lower cancer mortality overall than the United States despite higher incidence.

Significance:
These findings highlight the need to identify the causes of higher cancer incidence in the Northeast and the excess cancer mortality in NNE.
A readability analysis of patient education materials about chronic venous disease provided by professional vascular societies
Authors: Liao Jianyu , Wu Zhoupeng , Zhao Jichun 
Published: July 2023

Background Professional vascular societies and forums have disseminated patient information on education materials about chronic venous disease (CVD) via their official websites. While online patient education material is readily available with an Internet connection, its practical utility may be limited for patients with low health literacy. Methods Six readability measures were used to evaluate the patient education materials regarding CVD published by 12 professional medical societies. Results Patient education materials on CVD vary considerably in length among medical societies, and their comprehensibility points toward a difficult level. The mean readability score was 11.20, prominently above the National Institutes of Health (NIH) and American Medical Association (AMA) recommendations. Conclusion Our analysis of patient education materials produced by 12 professional vascular societies and forums found that all materials exceeded the recommended readability levels. The innovative section “Information for patients'' in the ESVS CVD guidelines also exceeded these levels. Improving the readability of patient education materials is essential to meet patient health literacy standards and might improve patient outcomes in managing CVD.
Career Intentions and the Determining Factors among Health Science Students: A Systematic Review
Authors: Stanley Njaka , Binti Bakar Raishan Shafini , Cheng Kueh Yee , Nwedu Aaron Beryl , Binti Hassan Intan Idiana 
Published: July 2023

Background Health systemsneed adequate personnelin order to function; improvements in health-care services delivery, and coverage and the enjoyment of standard healthcare as a right, depend on the availability, mixture, quality, and accessibility of the health-care workforce. Purpose This review aimed to synthesize reliable evidence ondetermining factors among health science students’ career choices to enhance policy advocacy for better health-care delivery. Method We sourced empirical studies from Scopus, PubMed, ScienceDirect and Google Scholar. From a total of 9,056 researcharticlesfrom 2010 to 2022, 27 studies with a total of 45,832 respondents met the inclusion criteria. Results The majority of the studies were of medical students; internal medicine was the commonest choice (64.3%), with psychiatry and public health receiving lesser attention. In the four available studies of nursing students, midwifery was not chosen at all. There is a paucity of studies on this all-important concept for nursing students. The determining factors of choice of specialty were in four themes: personal, socioeconomic, professional, and educational/policy. Among the barriers to choosing particular specialties were low prestige among colleagues, stigma, long working hours, and poor public recognition. Conclusion The career choices of health science students do not reflect an adequate mix of health-care team members to meet the health-care needs of the world. Reforms of policy and educational training are needed.
Cost and Clinical Outcomes Evaluation Between the Endoaortic Balloon and External Aortic Clamp in Cardiac Surgery
Authors: Balkhy Husam H. , Grossi Eugene A. , Kiaii Bob , Murphy Shannon M.E. , Kitahara Hiroto , Guy T. Sloane , Lewis Clifton 
Published: July 2023

Objective: Endoaortic balloon occlusion facilitates cardioplegic arrest during minimally invasive surgery (MIS). Studies have shown endoclamping to be as safe as traditional aortic clamping. We compared outcomes and hospital costs of endoclamping versus external aortic occlusion in a large administrative database. Methods: There were 52,882 adults undergoing eligible cardiac surgery (October 2015 to March 2020) identified in the Premier Healthcare Database. Endoclamp procedures ( n = 419) were 1:3 propensity score matched to similar procedures using external aortic occlusion ( n = 1,244). Generalized linear modeling measured differences in in-hospital complications (major adverse renal and cardiac events, including mortality, new-onset atrial fibrillation, acute kidney injury [AKI], myocardial infarction [MI], postcardiotomy syndrome, stroke/transient ischemic attack [TIA], and aortic dissection) and length of stay (LOS). Results: The mean age was 63 years, and 53% were male ( n = 882). The majority (93%, n = 1,543) were mitral valve procedures, and 17% of procedures ( n = 285) were robot-assisted. Total hospitalization costs were not statistically significantly different between the 2 groups ($52,158 vs $49,839, P = 0.06). The median LOS was significantly shorter in the endoclamp group (incident rate ratio = 0.87, P < 0.001). Mortality, atrial fibrillation, AKI, and stroke/TIA were similar between the 2 groups. MI and postcardiotomy syndrome were lower in the endoclamp group (odds ratio [OR] = 0.14, P = 0.006, and OR = 0.27, P = 0.005). There were no aortic dissections in the endoclamp group. Conclusions: Aortic endoclamping in MIS was associated with similar costs, shorter LOS, no dissections, and comparably low mortality and stroke rates when compared with external clamping in this hospital billing dataset. These results demonstrate the clinical safety and efficacy of endoaortic balloon clamping in a real-world setting. Further studies are warranted.
Sternal-Sparing Surgical Options in Combined Aortic Valve and Coronary Artery Disease: Proof of Concept
Authors: Watanabe Tatsuya , Kitahara Hiroto , Shah Atman P. , Blair John , Nathan Sandeep , Balkhy Husam H. 
Published: July 2023

Objective: The standard management of concomitant aortic valve (AV) and coronary artery disease has been coronary artery bypass and AV replacement (AVR). With the advent of minimally invasive options, many isolated lesions have been successfully managed using a sternal-sparing approach. In our institution, patients with isolated AV disease are offered minimally invasive surgical or transcatheter AVR, and those with isolated coronary artery disease are routinely managed with robotic totally endoscopic coronary artery bypass or percutaneous coronary intervention. Various combinations of these techniques can be used when a sternal-sparing posture is desired because of patient risk or preference. The aim of this study was to review the outcomes in patients with combined AV and coronary disease who were managed using sternal-sparing approaches. Methods: We reviewed the records of 10 patients in our minimally invasive surgical database who presented with concomitant AV and coronary artery disease and underwent combined sternal-sparing management of these 2 lesions using various combinations of minimally invasive approaches. Results: Four patients had totally endoscopic coronary artery bypass and minimally invasive AVR at the same time, 2 patients underwent transcatheter AVR followed by totally endoscopic coronary artery bypass, and 4 patients underwent minimally invasive AVR with percutaneous coronary intervention. There was no 30-day mortality. The duration of postoperative surgical hospital stay was 3.1 ± 0.9 days. Conclusions: Sternal-sparing approaches in combined AV and coronary artery disease are feasible with patient-specific treatment selection of minimally invasive techniques.
Total joint arthroplasty versus trapeziectomy in the treatment of trapeziometacarpal joint arthritis: a randomized controlled trial
Authors: de Jong Tjeerd R. , Bonhof-Jansen Elske E. D. J. , Brink Sander M. , de Wildt Ramon P. , van Uchelen Jeroen H. , Werker Paul M. N. 
Published: July 2023

The aim of this double anonymized, randomized controlled trial was to determine whether total joint arthroplasty has superior outcomes than trapeziectomy 1 year after surgery for trapeziometacarpal osteoarthritis. A total of 62 women aged 40 years and older, scheduled for surgery for stage II or III osteoarthritis of the trapeziometacarpal joint, were included and randomized to trapeziectomy or total joint arthroplasty. The primary outcome was the total score of the Michigan Hand Outcomes Questionnaire. Secondary outcomes were the Michigan Hand Outcomes Questionnaire subscale scores, Disability of the Arm, Shoulder and Hand Questionnaire, active range of motion, strength, return to work, patient satisfaction and complications. Data were collected at baseline and at 3 and 12 months. At 1 year, we found no superiority of total joint arthroplasty over trapeziectomy regarding the total score of the Michigan Hand Outcomes Questionnaire. The total joint arthroplasty did show a significant advantage in strength and range of motion. Level of evidence: I