bluuebunny/crossref_metadata_2025_split huggingface dataset:
On‐Site Therapeutic Drug Monitoring of Paracetamol Analgesic in Non‐Invasively Collected Saliva for Personalized Medicine
Authors: Gomes Nathalia O. , Raymundo‐Pereira Paulo A. 
Published: January 2023

AbstractParacetamol or acetaminophen is the main non‐opioid analgesic recommended for mild pain by the World Health Organization (WHO) analgesic ladder. However, the high levels used of paracetamol are associated with the hepatotoxicity and nephrotoxicity caused by accumulation of toxic metabolites. The sensor is produced on a polyester substrate containing a full electrochemical device with working, auxiliary, and reference electrodes in which, guiding personalized medicine solutions are not reported. Temporal paracetamol profiles in human saliva are performed with the subject taking different amounts of commercial analgesic pills. The variation of saliva paracetamol levels is demonstrated to be interference free from electroactive interfering species and human saliva constituents. In addition, the sensor displays to be useful as a disposable device for the fast detection of paracetamol in untreated raw saliva following pill intake. The maximum concentration (Cmax) and half‐life time (t1/2) for paracetamol are 143.27 µm and 110 min. The results demonstrate the potential of a simple strategy with electrochemical devices for noninvasive personalized therapy toward guiding drug interventions through tracking of active substance, detecting, and correcting insufficiency of absorption to meet individual needs avoiding overdoses, side effects, and intoxication.
In Situ Growth of Iron Sulfide on Fast Charge Transfer V2C‐MXene for Superior Sodium Storage Anodes
Authors: Xiong Zhihao , Shi Haofeng , Zhang Wenyuan , Yan Jingtao , Wu Jun , Wang Chengdeng , Wang Donghua , Wang Jiashuai , Gu Yousong , Chen Fu‐Rong , Yang Yongzhen , Xu Bingshe , Yan Xiaoqin 
Published: January 2023

AbstractDue to the upstream pressure of lithium resources, low‐cost sodium‐ion batteries (SIBs) have become the most potential candidates for energy storage systems in the new era. However, anode materials of SIBs have always been a major problem in their development. To address this, V2C/Fe7S8@C composites with hierarchical structures prepared via an in situ synthesis method are proposed here. The 2D V2C‐MXene as the growth substrate for Fe7S8 greatly improves the rate capability of SIBs, and the carbon layer on the surface provides a guarantee for charge–discharge stability. Unexpectedly, the V2C/Fe7S8@C anode achieves satisfactory sodium storage capacity and exceptional rate performance (389.7 mAh g−1 at 5 A g−1). The sodium storage mechanism and origin of composites are thoroughly studied via ex situ characterization techniques and first‐principles calculations. Furthermore, the constructed sodium‐ion capacitor assembled with N‐doped porous carbon delivers excellent energy density (135 Wh kg−1) and power density (11 kW kg−1), showing certain practical value. This work provides an advanced system of sodium storage anode materials and broadens the possibility of MXene‐based materials in the energy storage.
Regulation of Released Alkali from Gel Polymer Electrolyte in Quasi‐Solid State Zn–Air Battery
Authors: Li Haihan , Guo Jiaming , Mao Yanqi , Wang Guanbo , Liu Jinlan , Xu Yuncun , Wu Zhiwei , Mei Zhiwei , Li Wenqiong , He Yun , Liang Xiaoguang 
Published: January 2023

AbstractGel polymer electrolyte (GPE) in quasi‐solid state Zn–air battery (QSZAB) will release alkali during cycling, resulting in gradual dehydration of GPE, corrosion of Zn electrode, Zn dendrites growth, and therefore inferior performance. Here, hollow Sn microspheres are prepared on Zn substrate by the technique of colloidal self‐assembly. The inner surfaces of hollow Sn microspheres are modified by 2‐hydroxypropyl‐β‐cyclodextrin (hollow Sn‐inner HPβCD) to regulate the released alkali at GPE|anode interface. The hollow Sn‐inner HPβCD can lessen the leakage of released alkali, make stored alkali diffuse back to GPE during the charging process, and mitigate the loss of soluble Zn(OH)42−to suppress Zn dendrites growth. Resultantly, GPE in QSZAB with hollow Sn‐inner HPβCD exhibits a high retention capacity for alkaline solution. The cell also exhibits a long cyclic lifespan of 127 h due to the effective regulation of released alkali, which outperforms QSZAB without hollow Sn‐inner HPβCD by 7.94 times. This work rivets the regulation of released alkali at GPE|anode interface, providing new insight to improve QSZABs’ performance.
Heterointerface and Tensile Strain Effects Synergistically Enhances Overall Water‐Splitting in Ru/RuO2 Aerogels
Authors: Nicole Sui L. D. , Li Yinghao , Xie Wenjie , Wang Guangzhao , Lee Jong‐Min 
Published: January 2023

AbstractDesigning robust electrocatalysts for water‐splitting is essential for sustainable hydrogen generation, yet difficult to accomplish. In this study, a fast and facile two‐step technique to synthesize Ru/RuO2 aerogels for catalyzing overall water‐splitting under alkaline conditions is reported. Benefiting from the synergistic combination of high porosity, heterointerface, and tensile strain effects, the Ru/RuO2 aerogel exhibits low overpotential for oxygen evolution reaction (189 mV) and hydrogen evolution reaction (34 mV) at 10 mA cm−2, surpassing RuO2 (338 mV) and Pt/C (53 mV), respectively. Notably, when the Ru/RuO2 aerogels are applied at the anode and cathode, the resultant water‐splitting cell reflected a low potential of 1.47 V at 10 mA cm−2, exceeding the commercial Pt/C||RuO2 standard (1.63 V). X‐ray adsorption spectroscopy and theoretical studies demonstrate that the heterointerface of Ru/RuO2 optimizes charge redistribution, which reduces the energy barriers for hydrogen and oxygen intermediates, thereby enhancing oxygen and hydrogen evolution reaction kinetics.
Flexible Electronics Based on Organic Semiconductors: from Patterned Assembly to Integrated Applications
Authors: Liu Haoran , Liu Dong , Yang Junchuan , Gao Hanfei , Wu Yuchen 
Published: January 2023

AbstractOrganic flexible electronic devices are at the forefront of the electronics as they possess the potential to bring about a major lifestyle revolution owing to outstanding properties of organic semiconductors, including solution processability, lightweight and flexibility. For the integration of organic flexible electronics, the precise patterning and ordered assembly of organic semiconductors have attracted wide attention and gained rapid developments, which not only reduces the charge crosstalk between adjacent devices, but also enhances device uniformity and reproducibility. This review focuses on recent advances in the design, patterned assembly of organic semiconductors, and flexible electronic devices, especially for flexible organic field‐effect transistors (FOFETs) and their multifunctional applications. First, typical organic semiconductor materials and material design methods are introduced. Based on these organic materials with not only superior mechanical properties but also high carrier mobility, patterned assembly strategies on flexible substrates, including one‐step and two‐step approaches are discussed. Advanced applications of flexible electronic devices based on organic semiconductor patterns are then highlighted. Finally, future challenges and possible directions in the field to motivate the development of the next generation of flexible electronics are proposed.
Hydroxyl‐Binding Energy‐Induced Kinetic Gap Narrowing between Acidic and Alkaline Hydrogen Oxidation Reaction on Intermetallic Ru3Sn7 Catalyst
Authors: Su Lixin , Fan Xinran , Jin Yiming , Cong Hengjiang , Luo Wei 
Published: January 2023

AbstractDeveloping highly efficient catalysts toward alkaline hydrogen oxidation reaction (HOR) and narrowing the kinetic gap between acidic and alkaline electrolytes are of great importance for the practical application of alkaline exchange membrane fuel cell . Herein, ordered Ru3Sn7/C intermetallic compound has been developed for the HOR under alkaline and acidic conditions. The authors demonstrate that the ordered intermetallic Ru3Sn7/C shows much enhanced HOR activity, stability, and CO‐tolerance compared with its disordered RuSn solid solution alloy counterpart. More importantly, the authors find that the kinetic gap of HOR between acidic and alkaline media is significantly narrowed in the as‐synthesized intermetallic Ru3Sn7/C catalysts. Combined experiment results and theoretical calculations, the authors understand that promoted hydroxyl‐binding energy on Ru3Sn7/C derived from the intermetallic‐induced strong electron interaction is responsible for the accelerated alkaline HOR performance and narrowed kinetic gap.
Efficient Charge Transfer and Effective Active Sites in Lead‐Free Halide Double Perovskite S‐Scheme Heterojunctions for Photocatalytic H2 Evolution
Authors: Lv Huijun , Yin Hongfei , Jiao Na , Yuan Chunyu , Weng Suting , Zhou Kailing , Dang Yangyang , Wang Xuefeng , Lu Zhen , Zhang Yongzheng 
Published: January 2023

AbstractThe practical application of lead‐free double perovskite Cs2AgBiBr6 in photocatalytic H2 evolution is still restricted due to the low activity and poor stability. The rational design of lead‐free halide double perovskites heterojunctions with efficient charge transfer and effective active sites is a potential route to achieve the ideal prospect. Herein, in this work an S‐scheme heterojunction of Cs2AgBiBr6 with enriched Br‐vacancies and WO3 nanorods (VBr‐Cs2AgBiBr6/WO3) obtaining excellent visible‐light responsive photocatalytic H2 evolution performance and durable stability is reported. The S‐scheme heterojunction driven by the unaligned Fermi levels of these two semiconductors ensures the efficient charge transfer at the interface, and density functional theory calculations reveal the enriched Br vacancies on Cs2AgBiBr6 (022) surfaces introduced by atom thermal vibration provide effective active sites for hydrogen evolution. The optimized VBr‐Cs2AgBiBr6/WO3 S‐scheme photocatalyst exhibits the photocatalytic hydrogen evolution rate of 364.89 µmol g−1 h−1 which is 4.9‐fold of bare VBr‐Cs2AgBiBr6 (74.44 µmol g−1 h−1) and presents long‐term stability of 12 h continuous photocatalytic reaction. This work provides deep insights into the photocatalytic mechanism of VBr‐Cs2AgBiBr6/WO3 S‐scheme heterojunctions, which emerges a new strategy in the applications of perovskite‐based photocatalysts.
Theoretical Prediction of Thermoelectric Performance for Layered LaAgOX (X = S, Se) Materials in Consideration of the Four‐Phonon and Multiple Carrier Scattering Processes
Authors: Bai Shulin , Zhang Jingyi , Wu Mengxiu , Luo Dongming , Wan Da , Li Xiaodong , Tang Shuwei 
Published: January 2023

AbstractInspired by the experimental achievement of layered LaCuOX (X = S, Se) with superior thermoelectric (TE) performance, the TE properties of Ag‐based isomorphic LaAgOX are systemically investigated by the first‐principles calculation. The LaAgOS and LaAgOSe are direct semiconductors with wide bandgaps of ≈2.50 and ≈2.35 eV. Essential four‐phonon and multiple carrier scattering mechanisms are considered in phonon and electronic transport calculations to improve the accuracy of the figure‐of‐merit (ZT). The p‐type LaAgOX (X = S, Se) shows excellent TE performance on account of the large Seebeck coefficient originated from the band convergency and low thermal conductivity caused by the strong phonon–phonon scattering. Consequently, the optimal ZTs along the out‐of‐plane direction decrease in the order of n‐type LaAgOSe (≈2.88) > p‐type LaAgOSe (≈2.50) > p‐type LaAgOS (≈2.42) > n‐type LaAgOS (≈2.27) at 700 K, and the optimal ZTs of ≈1.16 and ≈1.29 are achieved for p‐type LaAgOS and LaAgOSe at the same temperature. The present work would provide a deep insight into the phonon and electronic transport properties of LaAgOX (X = S, Se), but also could shed light on the way for the rational design of state‐of‐the‐art heteroanionic materials for TE application.
Ready for Read‐Alouds: 10 Practices for Book‐Sharing with Infants and Toddlers
Authors: Vallotton Claire D. , Gardner‐Neblett Nicole , Kim Loria , Harewood Tamesha , Duke Nell K. 
Published: January 2023

AbstractExperiences with books before age three predict children's motivation to read (Bus et al., 1995), and can support the development of vocabulary, communication, and symbolic skills (Scarborough, 2001). Sharing books with infants and toddlers is different than reading aloud to older children. For example, it is important to attend more closely to infants' eye gaze and to support toddlers to respond with gestures. This article presents 10 research‐based practices for book‐sharing with infants and toddlers to foster love of reading and emergent literacy skills. For each practice, we provide examples with preverbal infants and newly verbal toddlers. We encourage teachers of reading to use these practices in their interactions with infants and toddlers and to use their role as literacy leaders to share the practices with childcare providers, families, and others who work with this age group.
The best colleges for adult learners never stop working to improve
Authors: Sutton Halley 
Published: January 2023

I'm a farm kid. I grew up in a small town in Nebraska — there were a whopping 1,000 people in my town,” said Jerrid P. Freeman, Ph.D., Vice President for Student Affairs and Enrollment Management at Northeastern State University in Oklahoma. “It was one of those things where college was just not on my radar.” Freeman pursued his undergraduate degree at the University of Nebraska at Kearney while playing sports, and came to love the higher education environment, going on to earn his master's and doctorate.
Flock size and structure influence reproductive success in four species of flamingo in 540 captive populations worldwide
Authors: Mooney Andrew , Teare J. Andrew , Staerk Johanna , Smeele Simeon Q. , Rose Paul , Edell R. Harrison , King Catherine E. , Conrad Laurie , Buckley Yvonne M. 
Published: January 2023

AbstractAs global wildlife populations continue to decline, the health and sustainability of ex situ populations in zoos and aquariums have become increasingly important. However, the majority of managed ex situ populations are not meeting sustainability criteria and are not viable in the long term. Historically, ex situ flamingo (Phoenicopteriformes) populations have shown low rates of reproductive success and improvements are needed for long‐term viability. Both flock size and environmental suitability have previously been shown to be important determinants of ex situ flamingo reproductive success in a limited number of sites in some species. Here we combined current and historic globally shared zoological records for four of the six extant species of flamingo (Phoeniconaias minor, Phoenicopterus chilensis, Phoenicopterus roseus, and Phoenicopterus ruber) to analyze how flock size, structure, and climatic variables have influenced reproductive success in ex situ flamingo populations at 540 zoological institutions from 1990 to 2019. Flock size had a strong nonlinear relationship with reproductive success for all species, with flock sizes of 41–100 birds necessary to achieve ca. 50% probability of reproduction. Additionally, an even sex ratio and the introduction of new individuals to a flock both increased ex situ reproductive success in some cases, while climatic variables played a limited role. We demonstrate the conservation management potential from globally shared zoological data and provide species‐specific management recommendations to increase the reproductive success of global ex situ flamingo populations: minimum flock sizes should be increased, and we encourage greater collaboration between individual institutions and regional associations in exchanging birds between flocks.
Prevalence and correlates of perinatal depression
Authors: Al-abri Khalood , Edge Dawn , Armitage Christopher J. 
Published: January 2023

Abstract
Purpose
This systematic review of systematic reviews aims to provide the first global picture of the prevalence and correlates of perinatal depression, and to explore the commonalities and discrepancies of the literature.

Methods
Seven databases were searched from inception until April 2022. Full-text screening and data extraction were performed independently by two researchers and the AMSTAR tool was used to assess the methodological quality.

Results
128 systematic reviews were included in the analysis. Mean overall prevalence of perinatal depression, antenatal depression and postnatal depression was 26.3%, 28.5% and 27.6%, respectively. Mean prevalence was significantly higher (27.4%; SD = 12.6) in studies using self-reported measures compared with structured interviews (17.0%, SD = 4.5; d = 1.0) and among potentially vulnerable populations (32.5%; SD = 16.7, e.g. HIV-infected African women) compared to the general population (24.5%; SD = 8.1; d = 0.6). Personal history of mental illness, experiencing stressful life events, lack of social support, lifetime history of abuse, marital conflicts, maternity blues, child care stress, chronic physical health conditions, preeclampsia, gestational diabetes mellitus, being exposed to second-hand smoke and sleep disturbance were among the major correlates of perinatal depression.

Conclusion
Although the included systematic reviews were all of medium–high quality, improvements in the quality of primary research in this area should be encouraged. The standardisation of perinatal depression assessment, diagnosis and measurement, the implementation of longitudinal designs in studies, inclusions of samples that better represent the population and better control of potentially confounding variables are encouraged.
Modelling and forecasting risk dependence and portfolio VaR for cryptocurrencies
Authors: Cheng Jie 
Published: January 2023

AbstractIn this paper, we investigate the co-dependence and portfolio value-at-risk of cryptocurrencies, with the Bitcoin, Ethereum, Litecoin and Ripple price series from January 2016 to December 2021, covering the crypto crash and pandemic period, using the generalized autoregressive score (GAS) model. We find evidence of strong dependence among the virtual currencies with a dynamic structure. The empirical analysis shows that the GAS model smoothly handles volatility and correlation changes, especially during more volatile periods in the markets. We perform a comprehensive comparison of out-of-sample probabilistic forecasts for a range of financial assets and backtests and the GAS model outperforms the classic DCC (dynamic conditional correlation) GARCH model and provides new insights into multivariate risk measures.
Effect of total knee arthroplasty for valgus knee correction on clinical outcome and patellar position
Authors: Zhou Liang , Dai Xuening , Zhou Zhongyuan , Kong Qian , Duan Guoqing , Zhang Yuanmin 
Published: January 2023

Abstract
Purpose

The purpose was to investigate the effect of different degrees of valgus deformity correction on patellar position and clinical outcome in patients with valgus knees after total knee arthroplasty (TKA).

Methods
We retrospectively analyzed and followed 118 patients with valgus knees. Based on the post-operative hip–knee–ankle (HKA), patients were divided into three groups: neutral (±3°), mild (3–6°), and severe (> 6°). Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), range of motion (ROM), and Knee Society Score (KSS) were used to evaluate post-operative clinical efficacy. Also, the patellar tilt angle (ε-angle), congruence angle (θ-angle), and Insall–Salvati index (ISI) were used to represent the patellar position. Post-operative observation indicators included HKA, angle of the femur (α-angle), tibial angle (β-angle), femoral component flexion angle (γ-angle), and tibial component posterior slope angle (δ-angle).

Results
All patients showed significant improvements in HKA, ROM, WOMAC, and KSS after operation (P < 0.001). Regarding patellar position, the ISI values decreased to varying degrees (P < 0.05). The patellar tilt angle was significantly increased in the severe valgus group compared to that in the mild valgus and neutral groups (P < 0.001). Univariate analysis showed that the degree of post-operative residual valgus was significantly affected by WOMAC, KSS, α-, ε-, and θ-angles.

Conclusion
Minor valgus undercorrection did not affect the short-term outcome after TKA; however, when the residual valgus angle was > 6°, the post-operative scores were significantly reduced. Inadequate valgus correction does not result in significant changes in patellar height but may increase the risk of poor patellar tracking.
Thoracoscopic vs open repair of congenital diaphragmatic hernia after extracorporeal membrane oxygenation: a comparison of intra-operative data
Authors: Budzanowski Annita , Loukogeorgakis Stavros , Mullassery Dhanya , Blackburn Simon , Curry Joe , Ioannou Ioannis , Ali Usman , Cross Kate , Giuliani Stefano , De Coppi Paolo 
Published: January 2023

Abstract
Purpose
ECMO is an escalation treatment for hypoxic respiratory failure in patients with CDH. Open repair has been advocated after ECMO indicating that physiological changes associated to thoracoscopic repair were not well tolerated.

Methods
We have performed a retrospective review of all patients who underwent ECMO prior CDH repair over a 7 year period (2015–2021). Outcome measures were intra-operative Ph, PCO2, PO2 and FiO2 at 30 min, 1 h 30 min, and 2 h 30 min of surgery, operative time and recurrence rate. Data are shown in median (range).

Results
Eleven patients required ECMO prior CDH repair. Six of eleven (55%) were done thoracoscopically (Group A) and five of eleven (45%) via laparotomy (Group B). Two of six (33%) patients (Group A) were converted to a laparotomy, one of six (16%) patient developed a recurrence, and there was no recurrence in Group B. Two of five (40%) patients died within the first 60 days of life, whilst there was no death in Group A. Intra-operative values are shown below.

Conclusion
Whilst this is a preliminary report of a limited number of patients, there is no obvious difference of intra-operative blood gas parameters during surgical repair in patients after ECMO. Thoracoscopic CDH repair may be considered in patients after ECMO.