bluuebunny/crossref_metadata_2025_split huggingface dataset:
Teknologikonferanse – tilrettelegging for tverrfagleg undervisning om elektrisk energi
Authors: Mestad Idar 
Published: July 2023

This study presents the Technology Conference, a didactical design aimed to facilitate cross-disciplinary teaching about how to produce electrical energy without climate gas emissions. The teaching unit is developed based on research literature and on experiences from four previous implementations in a pre-service teacher education course. Students’ discussions during a fifth implementation are recorded to investigate how different values are expressed when the students discuss and argue about different energy production methods.
Transcriptions from the discussions are analyzed thematically. Ten categories developed to describe the student discussions focus on environmental protection, economics, and technological optimism. The students express concerns about environmental protection and how technological development should benefit countries and persons with less financial opportunities. However, the students also express a pragmatic view on how nature should be used and an optimistic view how technology can solve future challenges. This view is discussed in relation to the concepts of hope and doubt, and it is also argued that the didactical design might stimulate this pragmatic view. Based on this, an adjusted didactical design is suggested that aims to stimulate more focus on the challenges and dilemmas new technologies might bring.
The feasibility, acceptability, and usability of telehealth visits
Authors: Sinha Gregory Naina , Shukla Alpana P. , Noel Jahi J. , Alonso Laura C. , Moxley Jerad , Crawford Andrew J. , Martin Peter , Kumar Sonal , Leonard John P. , Czaja Sara J. 
Published: July 2023

BackgroundTelemedicine is now common practice for many fields of medicine, but questions remain as to whether telemedicine will continue as an important patient care modality once COVID-19 becomes endemic. We explored provider and patients’ perspectives on telemedicine implementation.MethodsPhysicians from three specialties within the Department of Medicine of a single institution were electronically surveyed regarding their perceptions of satisfaction, benefits, and challenges of video visits, as well as the quality of interactions with patients. Patients were surveyed via telephone by the Survey Research Group at Cornell about participation in video visits, challenges encountered, perceived benefits, preferences for care, and overall satisfaction.ResultsProviders reported an overwhelmingly positive experience with video visits, with the vast majority agreeing that they were comfortable with the modality (98%) and that it was easy to interact with patients (92%). Most providers (72%) wanted to have more telemedicine encounters in the future. Key factors interfering with successful telemedicine encounters were technical challenges and insufficient technical support. Overall, patients also perceived video visits very positively regarding ease of communication and care received and had few privacy concerns. Some (10%–15%) patients expressed interest in receiving more technical support and training. There was a gradient of satisfaction with telemedicine across specialties with patients receiving weight management reporting more favorable responses while patients with lymphoma expressed more mixed responses.ConclusionBoth providers and patients found telemedicine to be an acceptable and useful modality to provide or receive medical care. The principal barrier to successful encounters was technical challenges.
Causal effect of early life adiposity on gestational diabetes mellitus and mediating roles of lipidomic biomarkers
Authors: Li Chuang , Li Na , Liu Caixia , Li Huan 
Published: July 2023

ObjectiveThe causal relationship between early life adiposity and gestational diabetes mellitus (GDM) and the underlying mechanisms remains unclear. This study aimed to investigate the independent causal association between early life adiposity and GDM and identify potential metabolic mediators and their mediating effects on this relationship.MethodsUsing genome-wide association study (GWAS) summary statistics from the publicly available database of early life adiposity (5,530 cases and 8,318 controls) and GDM (11,279 cases and 179,600 controls), a two-step, two-sample Mendelian randomization (MR) was conducted to estimate the causal mediation effects of lipidomic biomarkers including low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglyceride, apolipoprotein A-Ι, and apolipoprotein B on the relationship between early life adiposity and GDM.ResultsGenetically predicted childhood adiposity was positively associated with risk of GDM (OR: 1.21, 95%CI: 1.09–1.34, p = 4.58 × 10−4). This causal relationship remained after accounting for adult adiposity traits in the multivariable MR analyses. Two-step MR identified three candidate mediators that partially mediated the effect of early life adiposity on GDM, including HDL-C (5.81, 95%CI: 3.05–8.57%), apolipoprotein A-Ι (4.16, 95%CI: 1.64–6.69%), and triglyceride (2.20, 95%CI: 0.48–3.92%).ConclusionThis MR study demonstrated that the causal effect of childhood obesity on future GDM risk was independent of adult adiposity. We identified three mediators, including HDL-C, apolipoprotein A-Ι, and triglyceride, in this association pathway. Our results provide insights into the pathogenesis of GDM and suggest additional prevention and treatment targets for GDM related to early life adiposity.
Trends in volume-regulated anion channel (VRAC) research: visualization and bibliometric analysis from 2014 to 2022
Authors: Liu Tianbao , Li Yin , Wang Dawei , Stauber Tobias , Zhao Jiajun 
Published: July 2023

Objective: In this study, we utilized bibliometric methods to assess the worldwide scientific output and identify hotspots related to the research on the volume-regulated anion channel (VRAC) from 2014 to 2022.Methods: From Web of Science, we obtained studies related to VRAC published from 2014 to 2022. To analyzed the data, we utilized VOSviewer, a tool for visualizing network, to create networks based on the collaboration between countries, institutions, and authors. Additionally, we performed an analysis of journal co-citation, document citation, and co-occurrence of keywords. Furthermore, we employed CiteSpace (6.1. R6 Advanced) to analyzed keywords and co-cited references with the strongest burst.Results: The final analysis included a total of 278 related articles and reviews, covering the period from 2014 to 2022. The United States emerged as the leading country contributing to this field, while the University of Copenhagen stood out as the most prominent institution. The author with most publications and most citations was Thomas J. Jentsch. Among the cited references, the article by Voss et al. published in Science (2014) gained significant attention for its identification of LRRC8 heteromers as a crucial component of the volume-regulated anion channel VRAC. Pflügers Archiv European Journal of Physiology and Journal of Physiology-London were the leading journals in terms of the quantity of associated articles and citations. Through the analysis of keyword co-occurrence, it was discovered that VRAC is involved in various physiological processes including cell growth, migration, apoptosis, swelling, and myogenesis, as well as anion and organic osmolyte transport including chloride, taurine, glutamate and ATP. VRAC is also associated with related ion channels such as TMEM16A, TMEM16F, pannexin, and CFTR, and associated with various diseases including epilepsy, leukodystrophy, atherosclerosis, hypertension, cerebral edema, stroke, and different types of cancer including gastric cancer, glioblastoma and hepatocellular carcinoma. Furthermore, VRAC is involved in anti-tumor drug resistance by regulating the uptake of platinum-based drugs and temozolomide. Additionally, VRAC has been studied in the context of pharmacology involving DCPIB and flavonoids.Conclusion: The aim of this bibliometric analysis is to provide an overall perspective for research on VRAC. VRAC has become a topic of increasing interest, and our analysis shows that it continues to be a prominent area. This study offers insights into the investigation of VRAC channel and may guide researchers in identifying new directions for future research.
Mineral Chemistry of the Eagle Lake Granite Porphyry, Southwestern New Brunswick, Canada: Implications for Cu-Mo-Au Mineralization
Authors: Yousefi Fazilat , Lentz David R. , Thorne Kathleen G. 
Published: July 2023

Abstract
The oxidized I-type Eagle Lake Granite stock in southwestern New Brunswick, Canada, is texturally divided into porphyritic and equigranular phases. The porphyritic granite consists of phenocrysts (i.e., plagioclase, K-feldspar, quartz, and biotite) and microcrystalline groundmass with minor magnetite–ilmenite, titanite, apatite, and zircon. The equigranular phase has a similar primary mineral assemblage to the porphyritic phase. Their common magnetite-ilmenite-titanite assemblage reflects co-crystallization (magnetite series) from a magma imparting some redox control. However, these granite phases show minor potassic to propylitic alteration mineral assemblages with very minor sulfides, suggesting localized fluid–rock reaction.
The composition of plagioclase varies between albite and oligoclase, and K-feldspar is orthoclase commonly displaying considerable turbidity. The An% versus Al/(Ca+Na+K) data indicate that these feldspars are slightly aluminous, reflecting cryptic alteration. Biotite is rich in Fe, plotting near the boundary of primary and re-equilibrated biotite; these biotites formed at temperatures ranging from 670 to 725 °C, based on Ti-in-biotite thermometry. Secondary biotite grains are also locally evident, formed from magmatic-hydrothermal fluids. Secondary fine-grained biotite associated with fine-grained magnetite-pyrite indicates potassic alteration and related Cu±Mo±Au mineralization. Some of these various biotites are partially altered to chlorite at ∼301–361 °C. Like biotite, apatite occurs as both igneous and hydrothermal phases. Based on the concentration of F (4.21–2.90 wt.%), all these apatites are fluorapatites with content of light rare earth elements about 7000 ppm and Eu/Eu* = 0.16.
New Minerals from the Redmond Mine, North Carolina, USA: II. Cubothioplumbite and Hexathioplumbite, Two New Minerals Containing the Cubane-Like [Pb4(OH)4]4+ Structural Unit
Authors: Kampf Anthony R. , Smith Jason B. , Hughes John M. , Ma Chi , Emproto Christopher 
Published: July 2023

Abstract
The new minerals cubothioplumbite (IMA2021-091) and hexathioplumbite (IMA2021-092), both with the ideal formula [Pb4(OH)4]Pb(S2O3)3, were found in the Redmond mine, Haywood County, North Carolina, USA, where they occur together in a highly unusual secondary assemblage that comprises a variety of rare Pb-Zn-Cu sulfates, thiosulfates, and carbonates. Cubothioplumbite has the following properties: yellow equant crystals to about 0.5 mm; white streak; adamantine luster; brittle; Mohs hardness 3; conchoidal fracture; no cleavage; 5.748 g/cm3 calculated density; isotropic with n &gt; 2.00. Hexathioplumbite has the following properties: colorless hexagonal prisms to about 1 mm; white streak; adamantine luster; brittle; Mohs hardness 2½; curved fracture; no cleavage; 5.531 g/cm3 calculated density; uniaxial (−) with ω = 2.005(5) and ε = 1.995(5). Electron probe microanalyses provided the empirical formulae [Pb4(OH)4]Pb(S2O3)2.72(SO4)0.28 and [Pb4(OH)4]Pb(S2O3)2.68(SO4)0.32 for cubothioplumbite and hexathioplumbite, respectively. Cubothioplumbite is cubic, Pa, a = 14.9179(13) Å, V = 3319.9(9) Å3, and Z = 8. Hexathioplumbite is hexagonal, P63, a = 10.7213(10), c = 8.6541(6) Å, V = 861.49(17) Å3, and Z = 2. The structures of cubothioplumbite (R1 = 0.0354 for 1090 I &gt; 2σI) and hexathioplumbite (R1 = 0.0791 for 1062 I &gt; 2σI) both contain cubane-like [Pb4(OH)4]4+ structural units.
Exploring Learners' Learning Styles Preferences: Finding Out the Best Way to Teach ESP
Authors: Saptin Dwi Setyo Hastuti  
Published: July 2023

One important key to successful English for Specific Purposes (ESP) is through managing the classrooms. Identifying learners’ learning style preferences can assist teachers in creating a learning environment that is appropriate for the learners. The aim of this study is to explore learners’ learning styles and their impacts on the teaching of ESP. This study involved 284 learners from three different departments, i.e., the tour and travel business department, the tourism department, and the tourism department. The data was collected by using Reid’s Perceptual Learning Styles Preferences Questionnaire (PLSQ). This questionnaire divided learning styles into 4 categories, i.e., auditory, kinaesthetic, visual, and tactile learning styles. It also divided the learning styles into two, i.e., group and individual. This study revealed that most learners were auditory and kinaesthetic learners. Only a few learners were visual and tactile learners. This study also reveals that most learners preferred to work in groups rather than work individually. Considering these findings, learners must participate in determining the activities and environment for teaching a learning process to avoid mismatching between learners’ learning styles and teaching-learning methods. This study offers six recommendations that can be used as a guideline when conducting ESP in the various learning styles preferences.
Can Moringa oleifera Leaf Ethyl Acetate Extract Inhibit Candida albicans Planktonic Cell Growth and Biofilm Formation In Vitro?
Authors: Sulistyani Herastuti , Sulastri Siti , Risnawati Dewi , Agustina Dewi 
Published: July 2023

Introduction: Candida albicans (C. albicans) is the most common fungus found in the human oral cavity. This fungus has the ability to form a biofilm that causes infectious diseases in the oral cavity. Nowadays, the incidence of infectious diseases caused by C.albicans was increasing due to resistance to antifungal drugs. This study aimed to investigate the effect of Moringa oleifera ethyl acetate extract on the inhibition of C. albicans planktonic cell growth and biofilm formation in vitro. Methods: C. albicans (ATCC 10231) was the fungus used in this study. Determination of inhibition planktonic cell growth by microdilution method. The polystyrene microplate assay method was used to test the inhibition of C. albicans biofilm formation. The extract concentrations used in this study were 25%, 12.5%, 6.25%, 3.13%, and 1.57%, respectively. A crystal violet (CV) assay assessed the biofilm's inhibitory activity. Results: The minimal inhibitory concentration of Moringa oleifera leaf ethyl acetate extract against the planktonic form of C.albicans was found to be 1.57%. Starting at 6.25% concentration, Moringa leaf ethyl acetate extract inhibits the formation of C. albicans biofilm. Conclusion: Since Moringa oleifera leaf ethyl acetate extract inhibits C. albicans planktonic and biofilm formation, it has the potential to be developed as an alternative anti-fungal agent.
Keywords: Moringa leaf extract, planktonic cells, biofilm, Candida albicans
IMPROVING THE EFFICIENCY OF TURNING HEAT-RESISTANT ALLOYS BY INTRODUCING THE ENERGY OF AN ULTRASONIC FIELD INTO THE CUTTING ZONE
Authors: Khramov Alexander , Gorshkov Maxim , Nguyen Hanh , Kiselev Evgeny 
Published: July 2023

The use of difficult-to-process heat-resistant alloys is widely used in the design of aircraft engines and gas pumping units. As a rule, thin-walled shell structures are made from them, providing a high density of the layout (for example, blades, electric unicycles). The peculiarity of the manufac-ture of such structures is a small (compared to the occupied volume of the entire product) volume of metal, in which the heat generated during shaping is distributed. Given the low thermal conductivity of such alloys (up to 4-5 times less compared to steels), the shaping of parts from them is associated with the risk of warping in combination with low productivity of blade processing with carbide tools. More effective, but little studied is the processing with tools made of mineral ceramics with the introduction of the energy of the ultrasonic field into the cutting zone. The purpose of the research is to develop a high-performance technology for pre-processing workpieces made of heat-resistant alloys with tools made of mineral ceramics, characterized by a minimum depth of defects in the surface layer.
Methods. The research was carried out on machine tools in the manufacture of non-rigid parts of aircraft by turning blanks from the heat-resistant alloy HN45MVTYUBR with cutters made of mineral ceramics with the introduction of the energy of the ultrasonic field into the processing zone.
It has been established that the use of ultrasonic vibrations during pretreatment with mineral-ceramic tools without coolant can reduce the depth of the defective layer by up to one and a half times and increase productivity by up to 30 times.
Taking into account the reduction in the depth of the defective layer, it becomes possible to reduce the allowances for final processing, and consequently, to reduce the duration of the technological process and the cost of manufacturing parts.
Existence of solutions for higher order $\phi-$Laplacian BVPs on the half-line using a one-sided Nagumo condition with nonordered upper and lower solutions
Authors: Zerki A. , Bachouche K. , Ait-Mahiout K. 
Published: July 2023

In this paper, we consider the following \((n+1)\)st order bvp on the half line with a \(\phi-\)Laplacian operator \[ \begin{cases} (\phi(u^{(n)}))'(t) = f(t,u(t),\ldots,u^{(n)}(t)), & \text{a.e.},\, t\in [0,+\infty), \\ n \in \mathbb{N}\setminus\{0\}, \\ \\ u^{(i)}(0) = A_{i}, \, i=0,\ldots,n-2, \\ u^{(n-1)}(0) + au^{(n)}(0) = B, \\ u^{(n)}(+\infty) = C. \end{cases} \] The existence of solutions is obtained by applying Schaefer's fixed point theorem under a one-sided Nagumo condition with nonordered lower and upper solutions method where \(f\) is a \(L^{1}\)-Carathéodory function.
Long noncoding RNA (taurine upregulated gene 1) and micro RNA-377: emerging players in the development of metabolic syndrome among psoriasis patients
Authors: Alhelf Maha , Rashed Laila , Doss R. W. , Mohamed Sahar M. , Abd Elazeem Naglaa Adly) 
Published: July 2023

Abstract
Background
Psoriasis (PsO) is an immune-mediated dermatosis and systemic inflammatory condition that can affect the skin, joints, and other organs and tissues with a range of comorbidities. The activation of proinflammatory cytokines is the primary cause of the development of skin lesions in PsO. Patients with PsO have a higher risk of developing cardiovascular metabolic comorbidities; among these is the metabolic syndrome (MetS). Particularly, MetS is characterized by abdominal obesity, hypertension, hyperglycemia, and hyperlipidemia, has been linked to PsO. The connection between PsO and MetS is believed to be caused by PsO generating systemic inflammation, which then results in elevated inflammatory adipokines, endothelial dysfunction, and insulin resistance. Micro RNA-377 and long noncoding RNA taurine upregulated 1 (TUG1) are both involved in the control of a variety of inflammatory disorders in humans and can be employed as biomarkers for the diagnosis and prognosis of psoriasis. The aim of the present study is to establish a panel of biomarkers for the early diagnosis of MetS incidence in psoriasis and thereby, reducing its lethal consequences.

Results
In this study, 120 patients: 40 psoriatic patients, 40 psoriatic patients with metabolic syndrome, and 40 healthy subjects were conducted. Expressions of Long noncoding RNA Taurine Upregulated Gene-1 (TUG1), miRNA-377 and Peroxisome Proliferator-Activated Receptor-γ (PPAR-γ) were assessed in tissue lesion by real-time PCR. ELISA technique was carried out for the detection of serum levels of plasminogen activator inhibitor-1 (PAI-1) and transforming growth factor β (TGFβ). Moreover, miRNA-377 expression was significantly elevated with the simultaneous down-regulation of both TUG-1 and PPAR-γ in PsO-MetS group when compared to those of PsO and control groups. Furthermore, PAI-1 and TGFβ levels were higher in PsO-MetS than PsO.

Conclusions
The dysregulated levels of TUG-1, miRNA-377, PPAR-γ, PAI-1, and TGFβ, biomarkers may provide information about their potential role in the emergence of MetS in psoriasis patients.
Piękno, świat i moment. Estetyczne tło polityki Hannah Arendt w interpretacji Jima Josefsona.
Authors: Trzcinska Anna 
Published: July 2023

Artykuł analizuje estetyczną formę polityki Hannah Arendt w interpretacji Jima Josefsona. Zdaniem autora „Hannah Arendt’s Aesthetic Politics: Freedom and the Beautiful” - filozofka poszukiwała swego własnego „transcendentnego momentu” (der Augenblick) i w celu zidentyfikowania go analizowała prace takich myślicieli jak: Nietzsche, Kierkegaard, Jaspers, Heidegger, Kafka, Benjamin. Przemyślana krytyka każdego z powyższych nurtów pozwoliła jej sformułować własną koncepcję określoną przez Josefsona mianem „momentu estetycznego”. Wyodrębniając „wolność piękna”, jako trzecią twarz wolności na równi ze znanymi czytelnikom Arendt wolnością działania i umysłu, amerykański filozof w swej książce skupia się na wykazaniu, jak ta wolność, zakorzeniona w fenomenologii Jaspersa i niemetafizycznym odczytaniu Kanta, ma posłużyć za antidotum na wyobcowanie ze świata, które jego zdaniem, jest tematem spajającym wszystkie prace Arendt.
Application of the suture anchor in the treatment of Hoffa fractures of the lateral femoral condyle
Authors: Jiao Yingya , Suo Yanhui , Chen Junlin , Yan Ruihai , Yuan Zhongqiang , Shi Yinhu , Chang Cheng , Wei Meng 
Published: July 2023

Abstract
Background
To evaluate the feasibility and clinical effect of the suture anchor combined with external fixation in the treatment of the lateral femoral condyle Hoffa fracture.

Methods
In this study, a retrospective study was conducted to analyze the feasibility of treating fourteen patients (eight men and six women) with Hoffa fractures admitted to our Hospital from January 2016 to October 2021 with combined external fixation using incisional reduction anchor nailing. The age of the patients ranged from 23 to 45 years, with an average of 37.5 years. According to Letenneur’s classification, there were eight cases of type I, three cases of type II, and three cases of type III. The functional assessment of Letenneur was used to measure the clinical outcome.

Results
All patients had one-stage wound healing, and all patients were followed up for 12 to 18 months after surgery, and all fractures healed well, with normal knee flexion and extension activities, and no complications such as fracture displacement, anchor nail loosening, or fracture malunion were observed. The clinical outcome was evaluated according to the functional evaluation criteria of Letenneur et al. The clinical outcome of fourteen patients: excellent in thirteen cases and good in one case, with an overall excellent rate of 100%.

Conclusions
Our study results indicate that the use of anchor nailing combined with external fixation for Hoffa fractures of the femoral condyle has some clinical reference significance because it is less invasive, has fewer complications, does not require secondary removal, and is worthy of clinical application.
Trial registration: Retrospectively registered.