bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comprehensive assessment of subchronic low-dose exposure to doxorubicin in the Wistar rat model
Authors: Asanov M. A. , Poddubnyak A. O. , Muhamadiyarov R. A. , Sinitskaya A. V. , Khutornaya M. V. , Sinitsky M. Yu. 
Published: January 2025

Rationale. Doxorubicin is a chemotherapeutic antibiotic from the anthracycline class that has cumulative and dose-dependent cardiotoxic effects. The cardiotoxic properties of doxorubicin are manifested in characteristic pathologies of the heart and its microenvironment. Doxorubicin also exhibits genotoxic properties and is often used to model acute genotoxic effects in small laboratory animal models.Aim: To evaluate chronic low-dose exposure to doxorubicin in a Wistar rat model using cytogenetic methods and electron microscopy.Material and Methods. The study included two groups of 10 male Wistar rats: an experimental group (weekly doxorubicin in the tail vein 2 mg/kg for 4 weeks) and a control group (0.9% NaCl). A micronucleus test was used to evaluate genotoxic effects. Visualization of the myocardial structure was carried out using scanning electron microscopy in back-scattered electrons on an electron microscope.Results. The analysis showed a significant difference between the control (0.8%) and experimental groups (3.2%) in the level of polychrome erythrocytes with a micronucleus. It was found that rats from the experimental group were characterized by a significant decrease in the number of polychromatic red blood cells compared to the control group. In the experimental group, pronounced heterogeneity of the morphological structure of the myocardium was noted. Electron micrographs of hepatocytes from rats treated with doxorubicin showed degenerative changes in the structure of liver cells.Conclusion. The results of our study provide insight into the subacute effect of a small dose of doxorubicin on the heart, liver and hematopoietic system of normolipidemic Wistar rats. We have proposed mechanisms of interaction between important organs and systems of the body exposed to doxorubicin against the background of a general pathological condition. In the future, the nature of the toxic effects of lower and optimal doses of the mutagen in the context of subchronic cumulative exposure should be determined.
Iron deficiency and diastolic function in heart failure with preserved ejection fraction
Authors: Enina T. N. , Shirokov N. E. , Petelina T. I. , Gorbatenko E. A. , Kosterin M. D. , Yaroslavskay E. I. , Gapon L. I. 
Published: January 2025

Background. Despite the high prevalence of iron deficiency (ID) in heart failure with preserved ejection fraction (HFpEF), relationship between iron status indicators with the presence of the disease and parameters of diastolic function and myocardial strain have been insufficiently studied.Aim: To evaluate association of iron status indicators with the disease and parameters of diastolic function and myocardial strain in HFpEF patients.Material and Methods. According to diastolic stress test (DST) 67 patients with EF > 50% (65.8 ± 5.5 years) were divided into 2 groups: Gr.1 with HFpEF (n = 41), Gr.2 without HFpEF (n = 26). Parameters of diastolic function, left atrial reservoir strain (LASr), global longitudinal strain (GLS), diastolic reserve as per DST, serum iron (Fe), ferritin, iron transferrin saturation coefficient (ITSC) , hemoglobin (Hb), N-terminal pro B-type natriuretic peptide (NT-proBNP), C-reactive protein (CRP), creatinine, estimated glomerular filtration rate (eGFR) were assessed. Spearman method was used to study the relationships between iron status indicators and parameters of diastolic function, LASr, GLS; the cut-off point for ITSC was found by ROC analysis; factors associated with HFpEF were assessed via regression analysis.Results. In group 1, FCII (NYHA) was revealed more frequent with trends to greater prevalence in women, obesity, higher values of peak E, NT-proBNP, CRP > 3.0 mg/ml, lower values of E/e΄, LASr, Hb, ITSC. As per DST, differences between groups in all variables related elevation left ventricular filling pressure were registered; supreme load and heart rate were lowest in Gr1. Anemia was detected in 6 (9%) patients: 5 (12.2%) vs 1 (3.8%), respectively, p = 0.238; Iron deficiency in 27(40.3%): 18 (43.9%) vs 9 (34.6%), p = 0.157. Correlations were defined between Fe and ITSC with supreme load with DST and diastolic function parameters, but not with LASr and GLS. New cut-off point for ITSC = 29.2% (AUC = 0.699, p = 0.009; sensitivity = 71%, specificity = 69%) associated with HFpEF risk (OR 5.029 95% CI 1.575–16.055; p = 0.006) was revealed.Conclusion: Regardless of HFpEF, ID prevailed in patients aged over 60 years old, which determined the necessity of its screening study for the purpose of timely correction. Association between ITSC reduction less than 29.2% and the disease presence was found: risk of having HFpEF concurrently increased by five times. Interactions were registered between Fe and ITSC with supreme load and diastolic function parameters, but not with LASr and GLS. Higher incidence of CRP > 3.0 mg/ml with HFpEF confirmed pro-inflammatory status of the disease.
Is CT pulmonary angiography overutilized in the evaluation of patients with suspected pulmonary embolism? A retrospective study
Authors: Daoud Rabbani Mahmoud , Mohamed Ahmed Majeed , Almajthoob Muath Salahuddin , Fredericks Salim , Daoud Israa ElSayed , Daoud Moath Mahmoud , AlSaeed Mahmood 
Published: January 2025

Introduction Despite the high mortality rate of acute untreated pulmonary embolism (PE) at 30%, diagnosing PE is challenging. While the prevalence of PE has decreased in recent years, the overuse of computed tomography pulmonary angiography (CTPA) remains a concern. The National Institute for Health and Care Excellence (NICE) provides guidelines using the Wells score for PE assessment. The Royal College of Radiologists (RCR) recommends a positive yield of 15.4% - 37% for CTPA tests. This study assesses the positive yield of CTPA for suspected PE patients and evaluates the potential reduction through Wells score/D-dimer assessment as recommended by NICE. Methods All patients who underwent CTPA between September 1, 2019, and January 31, 2020, at Salmaniya Medical Complex were included. Data on patient demographics and pre-CTPA workup were collected from electronic patient records (EPR) and stored in MS Excel 2019 for analysis. Results Of 188 suspected PE patients (mean age 50 ±12.3 years; 62.8% female), 12.2% were diagnosed with PE. None had documented Wells scores. A low-risk Wells score (≤4) was assigned to 68.6% of patients, with only 26.1% undergoing D-dimer testing. PE was confirmed in 4 patients with low-risk Wells scores and elevated D-dimers. All 10 patients with low-risk Wells scores and negative D-dimers were PE-negative. Conclusion In total, 5.3% - 47.9% of the CTPAs conducted could have been avoided by following NICE guidelines. We propose integrating an algorithm-based checklist with validated tools like the Wells and Geneva scores into the ePMA system to guide appropriate CTPA referrals, promote evidence-based decision-making, reduce unnecessary imaging, and optimize patient care and resource use.
Peran Mediasi dalam Penyelesaian Sengketa Waris: Studi Putusan No. 545/Pdt. G/2019/Pa.Dps Pengadilan Agama Denpasar
Authors: Hamit Zairil , Risnawati Melia , Elfia Elfia , Zulfan Zulfan 
Published: January 2025

Artikel ini mengkaji bagaimana peranan mediasi dalam menyelesaikan sengketa kewarisan yang tertera pada akta perdamaian sengketa waris putusan Nomor. 545/pdt. G/2019/Pa.Dps. Penelitian bertujuan untuk melihat peranan mediasi dalam menyelesaikan sengketa kewarisan di pengadilan agama Denpasar. Penelitian ini menggunakan metode penelitian hukum normatif dengan mengunakan data sekunder berupa hasil putusan nomor 545/Pdt.G/2019/PA.Dps dan undang-undang yang terkait dengan hukum waris serta bahan hukum seperti buku, jurnal, dan sumber referensi lainnya yang dianggap relevan. Adapun hasil temuannya adalah bahwa peneyelesaian sengketa kewarisan dalam putusan Nomor. 545/pdt. G/2019/Pa.Dps. Dilakukan dengan meninjau, menginterpretasikan, dan membandingkan norma hukum yang relevan dengan kasus yang diteliti. Penulis menunjukkan bagaimana mediasi diimplementasikan dalam kasus spesifik tersebut, serta bagaimana mediasi tersebut berhasil membawa pihak-pihak yang bersengketa pada kesepakatan yang damai dan saling menguntungkan, meskipun mengesampingkan ketentuan bagian dalam hukum Islam namun, berhasil didamaikan secara kekeluargaan dan mufakat serta mengesampingkan ketentuan bagian dalam hukum Islam. Hal ini menunjukan bahwa mediasi berperan aktif dalam menyelesaikan perselisihan keluarga terkait dalam masalah warisan. Mediator membantu mereka berkomunikasi dengan baik dan menemukan jalan keluar yang adil bagi semua pihak. Hasil dari mediasi ini kemudian dicatat dalam akta perdamaian, yang membuat kesepakatan tersebut menjadi resmi dan sah secara hukum.
THE MEDIATING EFFECT OF ATTITUDES TOWARD SCIENCE IN THE PERCEPTIONS OF SCIENCE CLASSROOM ENVIRONMENT, FAMILY INVOLVEMENT, AND SCIENCE SELF-EFFICACY WITH SCIENCE ACHIEVEMENT
Authors: CANDIA LEONA A , Fah Lay Yoon 
Published: January 2025

Previous research has indicated that attitudes influence various factors contributing to scientific achievement. Inadequate performance in science can limit career opportunities, underscoring the importance of comprehending how attitudes towards science can enhance overall scientific achievement. This study explored the mediating effect of attitudes towards science for the relationships between perceptions of science classroom environment, family involvement, and science self-efficacy with science achievement. This research was conducted as a non-experimental quantitative research. Questionnaires from modified established instruments, Test of science-Related Attitudes, What Is Happening In this Class, Family Involvement Questionnaire- High School Version, Sources of science Self-Efficacy, and science Achievement Test, were sent out to participants via Google Form in different days for a span of two weeks. A total of 148 Form 2 upper-secondary school students from various districts in Sabah participated in this study. Data were analyzed using the Partial Least Squares Structural Equation Modeling method. The results revealed that Social Implications of science had a significant positive mediating effect between perceptions of science classroom environment and science achievement. Additionally, there was no significant mediating effect of attitudes toward science on the relationship between science self-efficacy, and family involvement with science achievement. Overall, this study suggests that an aspect of attitudes toward science, the Social Implications of science, was an important mediator between students’ perceptions of science classroom environment and science achievement. This meant that students would perform better in science when they perceived their science classroom better, in the condition that they value the implications that science brings to real life.
ENHANCING 〖PM〗_(2.5) PREDICTION IN KEMAYORAN DISTRICT, DKI JAKARTA USING DEEP BILSTM METHOD
Authors: Karin Nabila , Darmawan Gumgum , Hendrawati Triyani 
Published: January 2025

Worldwide air pollution is a concern, and this is especially true in Indonesia, where most people breathe air that is more contaminated than recommended by the WHO. The concentration of presents notable health hazards. The respiratory system is the primary route of absorption for , allowing it to enter the lung alveoli and enter the bloodstream. Given the significant health risks associated with exposure, accurate forecasting methods are crucial to anticipate and mitigate its effects. Traditional forecasting methods like ARIMA have limitations in handling non-linear and complex patterns. Therefore, an accurate machine learning method is needed to improve forecasting performance. This research employs Deep Bidirectional Long-Short Term Memory (BiLSTM), a deep learning model particularly suited for time series forecasting due to its ability to capture both past and future dependencies in sequential data. To achieve accurate and precise forecasts for predicting concentration levels in Kemayoran District in November , 2023 (24 hours), this research utilized hourly concentration data from May until October , 2023, using Deep BiLSTM. The outcomes demonstrated the efficiency of the model, attaining a Mean Absolute Percentage Error (MAPE) of 17.1540% (training) and 14.2862% (testing) with an 80:20 data split. The optimal parameters, which comprised 24 timesteps, Adam optimizers with a learning rate of 0.001, 16 batch sizes, 1000 epochs, and ReLU activation functions across multiple BiLSTM layers, showcased the model’s effectiveness in forecasting the concentration in Kemayoran District, DKI Jakarta, on November , 2023.
A STUDY ON THE STRUCTURE OF MATRICES RELATED TO THE VECH*, VECP*, AND VEC OPERATORS
Authors: Hidayah Nurul , Yanita Yanita , Nazra Admi 
Published: January 2025

The vec operator is an essential tool in matrix algebra that transforms a matrix into a column vector based on specific rules. This paper introduces two new operators, namely and , which take the main diagonal and supra-diagonal elements of the matrix, respectively. In this paper, we obtain the general form of the matrix , which transform to , with as a matrix of size . In addition, we also develop the general forms of matrices and , which transform into and into , with as a symmetric matrix of size . This study also explores the properties and relationships between these matrices and their relevance to duplication and commutation matrices, providing deeper insights into the structure and operations of matrices.
A FRACTIONAL-ORDER MATHEMATICAL MODEL OF THE SPREAD OF INFLUENZA
Authors: Akbar Abyan Daffa , Fatmawati Fatmawati , Ahmadin Ahmadin 
Published: January 2025

Influenza is an infectious disease that has become a public health concern and affects millions of people every year. In Indonesia, 1,527 people were recorded as being infected with influenza from May 2013 to April 2016. In this article, a fractional-order mathematical model of influenza spread was formulated in the sense of Caputo derivative. Based on the model analysis, we obtained two equilibrium points: the disease-free and endemic equilibria. The disease-free equilibrium point is locally asymptotically stable if the basic reproduction number is less than one. Meanwhile, the endemic equilibrium point exists and tends to be asymptotically stable whenever the basic reproduction number is greater than one. Next, a sensitivity analysis was carried out to determine whether changes in parameter values affect the increase or decrease in the value of the basic reproduction number. Lastly, the numerical simulation of the fractional-order model is demonstrated to support the analytical results.
CRAMER’S RULE IN INTERVAL MIN-PLUS ALGEBRA
Authors: Siswanto Siswanto , Septiany Ade Safira 
Published: January 2025

A min-plus algebra is a set , where is the set of all real numbers, equipped with the minimum and addition operations. The system of linear equations in min-plus algebra can be solved using Cramer's rule. Interval min-plus algebra is an extension of min-plus algebra, with the elements in it being closed intervals. The set is denoted by equipped with two binary operations, namely minimum and addition . The matrix with notation is a matrix over interval min-plus algebra with size . Since the structure of min-plus algebra and interval min-plus algebra are analogous, the system of linear equations in interval min-plus algebra can be solved using Cramer's rule. Based on the research results, the sufficient conditions of Cramer's rule in interval min-plus algebra are for , and . The Cramer rule is .
Strategies for Enhancing Co-existence in Diverse Social Groups
Authors: Sharma Lok Raj , Khulal Rupak 
Published: January 2025

Co-existence is a pleasing word to converse, but an intricate word to believe and follow in a real-life situation. This article aims to suggest effective strategies for enhancing co-existence in diverse social groups. To attain these objectives, the secondary data were congregated through a comprehensive review on co-existence and the strategies for enhancing co-existence from books, journal articles, and website materials published from the year 1971 to 2024. The article employed exploratory research and operated thematic analysis as its qualitative research design. It identifies. promoting inclusive education, encouraging intercultural dialogue, supporting community engagement initiatives, implementing anti-discrimination policies, promoting social integration programs, facilitating interfaith initiatives, encouraging multicultural policies, supporting civil society organizations, and promoting economic inclusion as the effective strategies for enhancing co-existence in diverse social groups. This article provides exquisite insights for leaders, policymakers and citizens, emphasizing that the feeling of co-existence is essential for the overall well-being of a nations and its citizens.
The Impact Of Marketing Ambidexterity On The Customer Sustainable Value An Analytical Survey For All Branches Of The Trade Bank Of Iraq(TBI) In Baghdad
Authors: ISRAA SHANAN THABIT  
Published: January 2025

يهدف البحث الحالي الى التعرف على اثر البراعة التسويقية متمثلة بأبعادها (استكشاف الفرص , استغلال الفرص , المرونة التسويقية ) في القيمة المستدامة للزبون بأبعادها (اكتساب الزبون , الاحتفاظ بالزبون , التوسع بالزبون ), من خلال استطلاع وتحليل اراء عينة من متخذي القرار والموظفين في فروع المصرف التجاري العراقي( TBI ) في مدينة بغداد , والتي بلغ عددها(65 ) فرداً , و قد استخدمت الاستبانة كأداة رئيسة لجمع البيانات والمعلومات من العينة المبحوثة , و حللت اجاباتهم باستخدام البرنامج الاحصائي( SPSS V. 25) , و البرنامج الاحصائي( (Smart PLS في احتساب الاوساط الحسابية والانحرافات المعيارية واختبار ( f ) , و معامل الانحدار البسيط , و الاهمية النسبية , و معامل التحديد ( R2 ) وتوصل البحث الى عدة استنتاجات اهمها وجود تأثير للبراعة التسويقية بجميع ابعاد القيمة المستدامة للزبون من وجهة نظر عينة البحث, كما قدم البحث عدة توصيات منها على ادارة المصرف الاهتمام بجميع ابعاد البراعة التسويقية باعتبارها ادواته التكتيكية لتنفيذ استراتيجيته التسويقية بصورة افضل .
The PATROL Model and Its Impact on Evaluating the Efficiency of Banking Performance: A LITERATURE REVIEW
Authors: Ayad Abed Hameed  , Osama Abdulsalam Jothr  , Dr. Khalid Sabah Ali  
Published: January 2025

هدفت الدراسة إلى تسليط الضوء على الآلية التي يمكن من خلالها استخدام نموذج PATROL في تقييم أداء المصارف، وذلك من خلال التعرف على كل من درجات تصنيف وآلية تطبيق نموذج PATROL بهدف الكشف عن نقاط القوة والضعف في الأداء المالي للمصارف وبالتالي رفع فاعلية وكفاءة الأداء المصرفي. وتوصلت الدراسة إلى أن نموذج PATROL يلعب دور هام في تقييم الأداء المصرفي من خلال عناصره الخمسة (كفاية رأس المال، الربحية، مخاطر الائتمان، التنظيم، السيولة) والتي تمكنه من توجيه متخذي القرارات في المصارف، وذلك من خلال الكشف عن نقاط القوة والضعف بهدف اتخاذ الإجراءات المناسبة في الوقت المناسب .
Effectiveness of Duet Conversation Strategy Using TikTok on Students’ Speaking Skill
Authors: Arochman Taufik , Wirawan Maulida Rhadhiya , Desvivia Talitha Rahmadhanti , Swari Dayinta Resty Nindya 
Published: January 2025

Students need to be able to speak English, yet many fail owing to a lack of classroom experience. While teachers often explain content, students mostly listen, which limits improvements. To solve this, innovative teaching strategies, like the duet conversation strategy, can help improve students' speaking abilities.The aim of this study was to find out the effectiveness of duet conversation strategy using TikTok on students’ speaking skill. The method of this study was pre-experimental research. The design used in this study was one group pre-test and post-test design for one group. The research participants were 31 students of a state junior high school in Magelang.Oral tests were carried out to collect research data. The data was analysed by a statistical expert using paired sample t-test. Based on the result of paired sample t-test, the Sig. (2-tailed) was 0.000 lower than 0.05. The result showed that duet conversation strategy on TikTok significantly affect students' speaking abilities. This study highlights the effectiveness ofduet conversation strategyusing TikTok can be implemented as an alternate media to assist learners in improving their speaking skill. However, there are still some difficulties such as the presence of unfamiliar words and lack of time when students are practicing using duet conversation on TikTok. Implementing duet conversation strategy on TikTok has the potential to increase students' speaking abilities, but it must be carefully planned and integrated into the curriculum to coincide with more formal and organized language learning objectives.
Drift
Authors: Aguiar Marian 
Published: January 2025

Abstract
The maritime refugee subject is constituted through the mobility of drift. This article interprets the representation of drift mobilities in Nam Le's 2008 story, “The Boat,” lê thi diem thúy's 2003 novel The Gangster We Are All Looking For, and Ocean Vuong's 2019 novel On Earth We're Briefly Gorgeous. It argues that these Vietnamese diasporic writers reinvent the image of “boat people,” severing it from its imperial past and authoring a new politics of belonging to oceanic movement. Le, lê and Vuong use representations of drift and maritime migration to challenge dominant post-war mobility narratives constituting a liberal subject of freedom. In the process, they reveal diasporic imaginaries that move fluidly between the past and the present, and between Vietnam and its diaspora.
Rail Mobility and the “China Model”
Authors: Brady Dylan 
Published: January 2025

Abstract
China's all-in embrace of high-speed rail transportation has put trains back in the global discourse, reshaping international and national imaginaries. Incorporating the Chinese case can substantially reshape our understanding of rail mobility can be and ought to be. The nationwide transformations wrought by Chinese rail offer mobility studies an opportunity to reengage with how mobility shapes community at the national scale, and the central role of the state highlights the peculiar connection between rail imaginaries and an interventionist state—paralleling a striking renaissance of rail imaginaries in Europe and the United States. As the “China Model” circulates across the globe and Chinese rail technologies proliferate, Chinese rail mobility will remain both theoretically and empirically significant.