bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALISIS FAKTOR DETERMINASI INDEKS PEMBANGUNAN MANUSIA DI PROVINSI BENGKULU
Authors: Ani Septri 
Published: June 2023

Penelitian ini bertujuan untuk menganalisis pengaruh belanja fungsi kesehatan, belanja fungsi pendidikan, pengangguran, dan pertumbuhan ekonomi terhadap indeks pembangunan manusia pada kabupaten/kota di Provinsi Bengkulu. Adapun jenis data dan alat analisis yang digunakan dalam penelitian ini adalah data panel dan analisi regresi linear berganda. Berdasarkan hasil regresi data panel, diperoleh fixed effect model sebagai model terbaik. Adapun hasil penelitian berdasarkan uji t diperoleh hasil bahwa secara parsial belanja fungsi kesehatan dan pengangguran memiliki pengaruh positif terhadap indeks pembangunan manusia pada α=5%, sedangkan belanja fungsi pendidikan dan pertumbuhan ekonomi memiliki pengaruh negatif dan signifikan terhadap indeks pembangunan manusia pada α=5%. Sementara berdasarkan uji F diperoleh hasil bahwa secara simultan belanja fungsi kesehatan, belanja fungsi pendidikan, pengangguran dan pertumbuhan ekonomi memiliki pengaruh positif terhadap indeks pembangunan manusia pada α=5% dengan hasil nilai R-square sebesar 0.9927 atau sebesar 99,27 persen.
Incidencia delictiva, percepción de inseguridad y cifra negra en Jalisco, 2018-2021
Authors: Guízar Mateos Isaí , Gonzalez Olivares Daniel 
Published: June 2023

La incidencia delictiva en el estado de Jalisco se ha reducido significativamente en los últimos años, pero esto no se ha reflejado en incrementos en la percepción de inseguridad. El propósito inicial de este documento es mostrar, de forma descriptiva, si la divergencia entre la evolución de la incidencia delictiva y la percepción de inseguridad, se puede explicar por la cifra negra de delitos. Se reporta que la cifra negra ha sido superior al noventa por ciento y que estadísticamente se ha mantenido sin cambios durante el periodo de análisis. Esto implica que la incidencia delictiva es sustancialmente mayor a la que indican los reportes oficiales pero que la reducción es genuina, por lo que no explica la divergencia entre los fenómenos. Profundizando en la percepción de inseguridad, se encuentra que sistemáticamente son más las mujeres que los hombres quienes reportan sentirse inseguras, y que la resistencia a reducir es únicamente a nivel estatal, pues en los últimos años cada vez más personas (de ambos sexos) se sienten mas seguras en su ambiente geográfico local. Finalmente, para explicar la magnitud de la cifra negra, indagamos la relevancia del deterioro en la confianza en las instituciones de seguridad pública y justicia, y el costo de transacción de interponer una denuncia. No se encuentra evidencia de deterioro (ni mejoría) en la confianza que inspiran las autoridades. Por otra parte, sí se encuentran indicios de que el costo de transacción es importante.
necesario fortalecimiento de la cultura de la legalidad para la contención de la violencia y la prevención del delito
Authors: Castro Figueroa Fernando Manuel , Olmeda García Marina del Pilar , Valdez Delgadillo Daniel Octavio 
Published: June 2023

Esta investigación tiene por objetivo analizar la importancia de la cultura de la legalidad en el ciudadano y orientar recomendaciones para su promoción e impulso por parte del Estado, la familia, la escuela, el sector empresarial y toda institución con capacidad liderazgo, para la contención de la violencia y la prevención del delito. Se concibe en este trabajo, que la transmisión de la cultura hacia las nuevas generaciones es uno de los objetivos centrales de toda sociedad, para la adquisición e interiorización de saberes, ideas, valores, creencias, costumbres y prácticas de nuestra identidad como persona en una comunidad determinada.
Las reflexiones que aquí se plantean, no pretende constituirse en un estudio teórico, ni aproximación analítica. Lo que se ofrece al lector, es el resultado de una reflexión ordenada e interrelación temática para identificar las perspectivas y desafíos de la Cultura de la legalidad y la importancia de reforzarla en los diferentes ámbitos del quehacer humano, familia, educación, trabajo, instituciones y vida comunitaria, como elemento de la formación valoral y su interiorización en el ser humano.
Pengaruh Beban Kerja dan Kompensasi terhadap Kinerja Karyawan pada PT Pinang Witmas Sejati Klk Desa Mangsang
Authors: Yanti Rena , Roswaty Roswaty , Emilda Emilda 
Published: June 2023

The purpose of this study is to determine the effect of workload and compensation on employee performance at PT Pinang Witmas Sejati KLK. The type of research used is quantitative research by distributing questionnaires through the Google Form. Sampling using saturated sampling technique using the entire population of 68 respondents. Sources of data in this study were primary data and secondary data using a purposive sampling technique. The results of the t test analysis show that workload has a positive and significant effect on employee performance at PT Pinang Witmas Sejati KLK, with significant value 0.000 <0.05 and tcount > ttable (-2,066 > 1.669) then H0 is rejected H1 is accepted. Compensation also partially has a positive and significant effect on employee performance at PT Pinang Witmas Sejati KLK, with significant value 0.016 <0.05 and tcount > ttable (2.470 > 1.669) then H0 is rejected H1 is accepted. Then the results of the F test analysis (simultaneous) show that workload and compensation together have a positive and significant effect on employee performance at PT Pinang Witmas Sejati KLK, with significant value 0.000 < 0.05 and Fcount > Ftable (33.366 > 3.99). From the test results the coefficient of determination (R2) is 0.507. This shows that the magnitude of the contribution between the Workload variable and the Compensation variable on Employee Performance is 50.7%.
Pengaruh Kompensasi dan Pengembangan Karir Terhadap Kinerja Karyawan pada PT. Aburahmi Di Penukal Abab Lematang Ilir (PALI)
Authors: Wulandari Putri , Roswaty Roswaty , Ulum Muhammad Bahrul 
Published: June 2023

The purpose of this study was to determine the Effect of Compensation and Career Development on Employee Performance at PT Aburahmi in PALI Regency. This research was conducted on PT. Aburahmi employees at Penukal Abab Lematang Ilir (PALI) jerus. 55 respondents as a sample. The data source in this study were secondary data and primary data using saturated sampling technique. Based on the results of the analysis, it shows that compensation and career development have a positive and significant effect on employee performance at Penukal Abab Lematang Ilir (PALI). F test (simultaneous) shows that Compensation and Csreer Development both have an effect on Employee Performance at Penukal Abab Lematang Ilir (PALI). Viewed and the coefficient of determination R Square is 0.274 which means 27,4% of employee performance variables can be explained by compensation and career development as much 72,6% can be explained by other variables not included in this study.
Peningkatan Kepuasan Kerja Melalui Lingkungan Kerja Karyawan CV Artha Mandiri Group Kabupaten Merangin
Authors: Devita Reni , Rasdi Rasdi , Azima Khuluqon 
Published: June 2023

CV Artha Mandiri Group is a company (Persero) engaged in equipment leasing and contracting. This study aims to describe job satisfaction, work environment, CV Artha Mandiri Group Merangin Regency, to find out and analyze the increase in job satisfaction and work environment. To answer the research objectives, the authors used theoretical studies related to research variables, namely job satisfaction, work environment. In addition, the authors also look for relevant previous research in the form of previous articles/journals and theses to support this research. This research uses quantitative methods. The population in this study were employees of CV Artha Mandiri GroupThe results of a simple linear regression analysis are obtained by the equation Y = 1.773 +0.032 Meanwhile, from the hypothesis testing carried out. The results obtained show that job satisfaction and work environment have increased significantly Merangin Regency, totaling 98 employees. Based on the results of data analysis and discussion in this study, it can be it can be concluded that CV Artha Mandiri Group Merangin Regency has high job satisfaction, unfavorable work environment. For this reason, it is hoped that in the future we can focus more on improving a more conducive work environment so that employee performance is higher than before.
Pengaruh Inventory Turnover dan Working Capital Turnover Dengan Current Ratio Sebagai Mediasi terhadap Harga Saham Pada Sub Sektor Industri Kabel di Bursa Efek Indonesia
Authors: Akbar Ali 
Published: June 2023

The purpose of this research is to know and analyze the influence of inventory turnover and working capital turnover mediating the current ratio on stock price in the cable industry sub-sector on the Indonesia stock exchange. This research used secondary data from annual financial statements and closing stock prices. The sample in the research is the cable industry sub-sector on the Indonesia Stock Exchange for the 2016-2021 period. The sampling method uses purposive sampling. Data analysis in this research used path analysis with SPSS software. The results of the research inform: ''1) indirectly inventory turnover and working capital turnover mediating the current ratio have insignificant effect on the stock price. 2) Inventory turnover and working capital turnover simultaneously have significant effect on current ratio. 3) Inventory turnover has negative and significant effect on current ratio. 4) Working capital turnover has positive and significant effect on current ratio. 5) Inventory turnover and working capital turnover simultaneously have significant effect on stock prices. 6) Inventory turnover has negative and significant effect on stock prices. 7) Working capital turnover has negative and insignificant effect on stock prices. 8) Current ratio has positive and insignificant effect on stock prices”.
Medeni Usul Hukukunda Yargılamanın Hızlandırılması ve Adalete Erişim Hakkı Bakımından Çevrimiçi Yargılama ve Yapay Zekanın Kullanımı
Authors: KARABEL Emine Gökçe , AYDEMİR Dilek 
Published: June 2023

Teknolojik gelişmelerin medeni usul hukuku bakımından ilk ve en etkili yansıması uluslararası pek çok ödüle de sahip olan UYAP sisteminin kurulması ile olmuştur. Elektronik tebligat yanında medeni yargılama hukuku bakımından dijitalleşme konusundaki en çarpıcı örneklerden birisi olarak karşımıza, özellikle 2020’de yapılan kanun değişikliği ile e-duruşma (HMK m.149) çıkmaktadır. Belli uyuşmazlıklar bakımından dava şartı olarak uygulanan arabuluculuğun icrası da artık çoğunlukla teknolojik imkanlar kullanılarak yapılmakta; yüz yüze yapılmamaktadır. Her ne kadar belli uyuşmazlıklar bakımından alternatif uyuşmazlık çözüm sistemleri uygulanıyor olsa da merkezi bir alternatif uyuşmazlık çözüm sistemi mevcut olmadığı gibi genel manada “small claim” yani küçük miktarlı ve nispeten daha az karmaşık uyuşmazlıklar bakımından özel bir uyuşmazlık çözüm usulü ya da yargılama usulü öngörülmüş değildir.
Uyuşmazlık çözümünde şirketlerin ve uyuşmazlık çözüm kurumlarının yanında artık devletlerin de yargı Örneğin, Birleşik Krallık’ta uygulanan “England Small Claim Procedure” yanında son yıllarda pilot uygulaması gerçekleştirilen “Çevrimiçi Sivil Para Alacakları (OCMC- Online Civil Money Claim) ve “Damages Claims Online Pilot (Çevrimiçi Hasar Talepleri Pilotu) uygulamaları da uyuşmazlığın Devletin yargı hizmetinin bir parçası olarak uyuşmazlık çözümünde kullanıldığı görülmektedir. İngiltere’deki bu pilot uygulamada dahi örnek alınan ve bu konudaki en başarılı örneklerden birisi olarak ise karşımıza Kanada’da uygulanan “Civil Resolution Tribunal” sistemi çıkmaktadır.
Yapay zeka konusunda en çok tartışılan konu ise yapay zekanın karar mercii olması ihtimalidir. Bunun dışında, özellikle karar taslağı oluşturulması, mevzuat ve spesifik ilmi ve kazai içtihat tespiti gibi konularda hakime yardımcı yapay zeka ve taraflara ve avukatlara yardımcı yapay zeka çalışmaları karşımıza çıkmaktadır.
Bu çalışmada hem yapay zeka alanındaki gelişmeler hem de karşılaştırmalı hukukta küçük uyuşmazlıkların çözümü için öngörülen bu sistemler örnek alınarak Türk hukuku bakımından özellikle yargıya erişim hakkı ve usul ekonomisi ilkesi gerçekleştirilmek üzere çevrimiçi uyuşmazlık çözüm sistemlerinin özellikle karmaşık olmayan küçük miktarlı uyuşmazlıklar için Türk Hukuku bakımından uygulanabilirliği; bu minvalde ve ayrıca diğer uyuşmazlıkların makul sürede sonuçlandırılmasına hizmet etmesi bakımından UYAP sisteminde yapılabilecek değişikliklere ilişkin önerilerimiz sunulacaktır.
Ticari İşlerde Faiz ve Sigorta Sözleşmelerine Yansıması
Authors: DEMİRCİ Serdar 
Published: June 2023

Ticari hükümler, ticari yaşamın gereklilikleri göz önünde bulundurularak, bazı hallerde genel hükümlerden farklı ilke ve esaslar içermektedir. Bu nedenle hukukumuzda bir işin ticari iş sayıldığı hallerde uygulanacak olan 6102 sayılı Türk Ticaret Kanunu’ndaki hükümler ile diğer kanunlarda yer alan ticari hükümler, adi işlerden farklı olarak kendine özgü hüküm ve sonuçları beraberinde getirmektedir.
Faiz hususunda da ticari işlerde, bileşik faiz uygulaması, faiz oranları, öngörülmese dahi faize hak kazanılması, daha yüksek oranda temerrüt faizi istenebilmesi noktalarında adi işlerden ayrıksı durumlara yer verilmiştir. Bilhassa, küresel gelişmelerin etkisiyle ülkemizin içinden geçtiği yüksek enflasyonist dönemde faiz konusu âkit tarafların hak ve menfaatlerinin korunması açısından günümüzde daha dikkat çeker hale gelmiştir.
Türk Ticaret Kanunu kapsamında ticari iş olarak kabul edilen sigorta sözleşmeleri de, sigorta sözleşmesinin konusu, sigorta uyuşmazlığının türü, tarafları, ilgili genel şartlar ve diğer kıstaslar dikkate alındığında faiz konusunda kendine has özellikler sergilemektedir. Bu çalışmada da, ticari iş ve ticari işlerde faiz kavramına değinerek, sigorta sözleşmelerinde hangi faiz türlerinin geçerli olduğu, faiz miktarının belirlenmesi ve faizin hangi tarihten itibaren talep edilebileceği konuları başta olmak üzere muhtelif yargı kararları çerçevesinde konuya ışık tutulmaya gayret edilmiştir.
Multi-omics analysis explores the effect of chronic exercise on liver metabolic reprogramming in mice
Authors: Lu Zhaoxu , Qian Ping , Chang Jiahui , He Xuejia , Zhang Haifeng , Wu Jian , Zhang Ting , Wu Jianxin 
Published: June 2023

Background: The effect of exercise on human metabolism is obvious. However, the effect of chronic exercise on liver metabolism in mice is less well described.Methods: The healthy adult mice running for 6 weeks as exercise model and sedentary mice as control were used to perform transcriptomic, proteomic, acetyl-proteomics, and metabolomics analysis. In addition, correlation analysis between transcriptome and proteome, and proteome and metabolome was conducted as well.Results: In total, 88 mRNAs and 25 proteins were differentially regulated by chronic exercise. In particular, two proteins (Cyp4a10 and Cyp4a14) showed consistent trends (upregulated) at transcription and protein levels. KEGG enrichment analysis indicated that Cyp4a10 and Cyp4a14 are mainly involved in fatty acid degradation, retinol metabolism, arachidonic acid metabolism and PPAR signaling pathway. For acetyl-proteomics analysis, 185 differentially acetylated proteins and 207 differentially acetylated sites were identified. Then, 693 metabolites in positive mode and 537 metabolites in negative mode were identified, which were involved in metabolic pathways such as fatty acid metabolism, citrate cycle and glycolysis/gluconeogenesis.Conclusion: Based on the results of transcriptomic, proteomics, acetyl-proteomics and metabolomics analysis, chronic moderate intensity exercise has certain effects on liver metabolism and protein synthesis in mice. Chronic moderate intensity exercise may participate in liver energy metabolism by influencing the expression of Cyp4a14, Cyp4a10, arachidonic acid and acetyl coenzyme A and regulating fatty acid degradation, arachidonic acid metabolism, fatty acyl metabolism and subsequent acetylation.
Combination of transbronchial cryobiopsy based clinic-radiologic-pathologic strategy and metagenomic next-generation sequencing for differential diagnosis of rapidly progressive diffuse parenchymal lung diseases
Authors: Sun He , Chen Rongzhang , Li Tian , Gao Jinli , Gu Xia , Zhu Xuyou , Jin Lianfeng , Shi Yi , Li Qiang 
Published: June 2023

BackgroundThe complicated spectrum of rapidly progressive diffused parenchymal lung diseases (RP-DPLD) creates obstacles to the precise diagnosis and treatment. We evaluated the differential diagnostic value of transbronchial cryobiopsy (TBCB) based clinic-radiologic-pathologic (CRP) strategy combined with bronchoalveolar lavage fluid (BALF) metagenomic next-generation sequencing (mNGS) in RP-DPLD patients.MethodsRP-DPLD patients who underwent the diagnostic strategy of TBCB-based CRP combined with BALF mNGS at Shanghai East Hospital from May 2020 to Oct 2022 were retrospectively analyzed. Clinical characteristics were summarized, including demographic data, high-resolution computed tomography (HRCT) findings, histopathology of TBCB and microbiological results. Diagnostic value of the combined strategy, as well as the sensitivity, specificity, and positive detection rates of mNGS were evaluated.ResultsA total of 115 RP-DPLD patients were enrolled, with a mean age of 64.4 years old and a male proportion of 54.8%. The pulmonary imaging findings in most patients were complex and diverse, with all patients showing bilateral lung diffuse lesions in HRCT, and progressively aggravated imaging changes within one month. After combining TBCB-based CRP strategy with mNGS, all participants received a corresponding diagnosis with 100% diagnostic yield. In these patients, 58.3% (67/115) were diagnosed with noninfectious RP-DPLD and 41.7% (48/115) with infection-related RP-DPLD. There were 86.1% of cases with known etiology according to the DPLD classification. BALF mNGS and traditional pathogen detection methods were performed in all patients, the positive detection rates were 50.4% (58/115) and 32.2% (37/115), respectively. Meanwhile, the mNGS showed significantly higher sensitivity and negative predictive value than the traditional pathogen detection methods for the diagnosis of infection-related RP-DPLD (100% vs 60.4% (p&lt;0.001), 100% vs 75.6% (p&lt;0.001), respectively). Among noninfectious RP-DPLD patients, the true negative rate of mNGS was 85.1% (57/67). All patients had their treatment regimen modified and the 30-day mortality was 7.0%.ConclusionThe novel strategy of TBCB-based CRP combined with mNGS provided dependable and sufficient evidence for the diagnosis, meanwhile further improved the accuracy of RP-DPLD treatment, as well as the prognosis of patients. Our results highlight the significant value of combined strategy in determining whether the RP-DPLD patients were infection associated or not.
Impact of atrial fibrillation on outcomes in asymptomatic severe aortic stenosis: a propensity-matched analysis
Authors: Oguz Didem , Huntley Geoffrey D. , El-Am Edward A. , Scott Christopher G. , Thaden Jeremy J. , Pislaru Sorin V. , Fabre Katarina L. , Singh Mandeep , Greason Kevin L. , Crestanello Juan A. , Pellikka Patricia A. , Oh Jae K. , Nkomo Vuyisile T. 
Published: June 2023

BackgroundAtrial fibrillation (AF) portends poor prognosis in patients with aortic stenosis (AS).ObjectivesThis study aimed to study the association of AF vs. sinus rhythm (SR) with outcomes in asymptomatic severe AS during routine clinical practice.MethodsWe identified 909 asymptomatic patients from 3,208 consecutive patients with aortic valve area ≤1.0 cm2 and left ventricular ejection fraction ≥50% at a tertiary academic center. Patients were grouped by rhythm at the time of transthoracic echocardiogram [SR: 820/909 (90%) and AF: 89/909 (10%)]. Propensity-matched analyses (2 SR:1 AF) matching 174 SR to 89 AF patients by age, sex, and clinical comorbidities were used to compare outcomes.ResultsIn the propensity-matched cohort, median age (82 ± 8 vs. 81 ± 9 years, p = 0.31), sex distribution (male 58% vs. 52%, p = 0.30), and Charlson comorbidity index (4.0 vs. 3.0, p = 0.26) were not different in AF vs. SR. Median follow-up duration was 2.6 (IQR: 1.0–4.4) years. The 1-year rate of aortic valve replacement (AVR) was not different (AF: 32% vs. SR: 37%, p = 0.31). All-cause mortality was higher in AF [hazard ratio (HR): 1.68 (1.13–2.50), p = 0.009]. Independent predictors of mortality were age [HR: 1.92 (1.40–2.62), p &lt; 0.001], Charlson comorbidity index [1.09 (1.03–1.15), p = 0.002], aortic valve peak velocity [HR: 1.87 (1.20–2.94), p = 0.006], stroke volume index [HR: 0.75 (0.60–0.93), p = 0.01], moderate or more mitral regurgitation [HR: 2.97 (1.43–6.19), p = 0.004], right ventricular systolic dysfunction [HR: 2.39 (1.29–4.43), p = 0.006], and time-dependent AVR [HR: 0.36 (0.19–0.65), p = 0.0008]. There was no significant interaction of AVR and rhythm (p = 0.57).ConclusionsLower forward flow, right ventricular systolic dysfunction, and mitral regurgitation identified increased risk of subsequent mortality in asymptomatic patients with AF and AS. Additional studies of risk stratification of asymptomatic AS in AF vs. SR are needed.
Association of handgrip strength with new-onset CKD in Korean adults according to gender
Authors: Lee Sung-Bum , Kim Miryung , Lee Hui-Jeong , Kim Jong-Koo 
Published: June 2023

IntroductionHandgrip strength (HGS) is an indicator of many diseases such as pneumonia, cardiovascular disease and cancer. HGS can also predict renal function in chronic kidney disease (CKD) patients, but the value of HGS as a predictor of new-onset CKD is unknown.Methods173,195 subjects were recruited from a nationwide cohort and were followed for 4.1  years. After exclusions, 35,757 participants remained in the final study, and CKD developed in 1063 individuals during the follow-up period. Lifestyle, anthropometric and laboratory data were evaluated in relation to the risk of CKD.ResultsThe participants were subdivided into quartiles according to relative handgrip strength (RGS). Multivariate Cox regression demonstrated that RGS was inversely associated with incident CKD. Compared with the lowest quartile, the hazard ratios (HRs) [95% confidence intervals (CIs)] for incident CKD for the highest quartile (Q4) was 0.55 (0.34–0.88) after adjusting for covariates in men and 0.51 (0.31–0.85) in women. The incidence of CKD decreased as RGS increased. These negative associations were more significant in men than in women. The receiver operating characteristic (ROC) curve showed that baseline RGS had predictive power for new-onset CKD. Area under the curve (AUC) (95% CIs) was 0.739 (0.707–0.770) in men and 0.765 (0.729–0.801) in women.ConclusionThis is the novel study demonstrating that RGS is associated with incident CKD in both men and women. The relationship between RGS and incident CKD is more significant in women than in men. RGS can be used in clinical practice to evaluate renal prognosis. Regular measurement of handgrip strength is essential to CKD detection.