bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of bonding effectiveness and fracture mechanics of different Adhesive systems to hypomineralized primary tooth enamel – An in - vitro study
Authors: SEKAR RAJAKUMAR , mp revanth , ponraj sujitha 
Published: April 2023

Abstract
Objective: To evaluate micro shear bond strength of different adhesives in hypomineralized primary teeth enamel.
Material and methods: A total of Thirty-five primary maxillary and mandibular molars were made in to 115 sections were preserved in 10% neutral buffered formalin at room temperature until sample preparation and utilized for the study. after discarding of 15 broken samples, 110 sections were utilized and divided in to four groups, control enamel group [with group I (N=25) and group II (N=25)] and hypomineralized enamel group [with group III (N=25) and group IV (N=25)]. The teeth samples were color coded and mounted in the acrylic block. Teeth were positioned horizontally and faced a wet 600-grit silicon carbide finishing paper to provide flat enamel surfaces with a 2 to 3 mm diameter surface roughness and shear bond strength was tested using Universal Testing Machine. The fractured surfaces were evaluated for failure modes using light microscopy.
Result: The bond strength of G-Premio bond is 21.56±6.72 MPa in control enamel and 12.8±1.52 MPa in hypo mineralized enamel. There exists a significant bond strength difference between both the adhesives to hypomineralized enamel (GC SOLARE universal bond= 7.07±3.90 MPa vs G- PREMIO bond 12.8±1.52 MPa; P≤.001). The most common failure is the cohesive failure
Conclusion: The present study indicates that the overall bonding of both adhesives to hypomineralized tooth is less effective than bonding to “normal” enamel. However, the shear bond strength of G-Premio bond to control enamel and hypomineralized enamel is significantly greater than GC Solare Universal Bond.
Clinical relevance: Restorative care of teeth with hypomineralization is difficult, and treatment decisions are influenced by a variety of factors including the severity of the disease, compliance and adhesive properties of the materials used and This is the first study to look at how self-etching adhesives affect hypomineralized primary enamel and helps in bonding strength of the affected enamel and based on this study results the bond strength of GP bond to control enamel and hypomineralized enamel is significantly greater than GC Bond.
Improvement of Conversion Cycle and Estimation of Capacitor Mismatch in Hybrid Analog-to-Digital Converters Using Flash and Successive Approximation Register
Authors: Hirai Ryukichi , Kishida Ryo , Matsuura Tatsuji , Hyogo Akira 
Published: April 2023

Abstract
This paper presents hybrid analog-to-digital converters (ADCs) using flash ADC and successive approximation register (SAR) ADC for improving conversion speed. The proposed architecture is the flash-hybrid-SAR architecture, which reduces the resolution of the flash ADC in the first stage by 1-bit and increases the resolution of the SAR ADC in the second stage compared to the conventional flash-radix-3-SAR architecture. The proposed ADC consists of the 3-bit flash ADC, 1-trit radix-3 SAR ADC and 4-bit two-bit/cycle SAR ADC to reduce the number of bit in the flash ADC. The proposed flash-hybrid-SAR ADC can reduce by half the number of resistors and comparators in the flash ADC from the conventional 8-bit hybrid flash-radix-3-SAR ADC with the same sampling rate at 142.8 MS/s. We simulated a flash-hybrid-SAR ADC with a capacitor mismatch of ±0.5% under six different conditions. The DNL is within ±0.5 LSB in all conditions when non-idealities other than the capacitor mismatch were eliminated. The INL is also within ±1 LSB in all conditions.
Does Patient Age Influence Procedural Management of Kidney Trauma?
Authors: Hakam Nizar , Abbasi Behzad , Ghaffar Umar , Li Kevin D , Patel Hiren , Jones Charles P , Cuschieri Joseph , Breyer Benjamin N. 
Published: April 2023

Abstract
Background We aimed to examine the association between patient age and procedural intervention, especially nephrectomy, in patients with renal trauma in the National Trauma Data Bank (NTDB).Study design We queried the 2013–2020 NTDB for adult renal trauma patients with an American Association for the Surgery of Trauma (AAST) grade. Patients without AAST grade or with no sign of life were excluded. We constructed logistic regression models to demonstrate the association between age and procedural intervention, including renal angioembolization, renorrhaphy and nephrectomy. Models were adjusted for patient, hospital, and clinical factors.Results Our cohort was comprised of 49,884 patients with renal trauma aged 18–89 years, of which 691 (1.4%), 995 (1.9%), and 3,366 (6.8%) underwent angioembolization, renorrhaphy, and nephrectomy, respectively. After adjusting for relevant variables, the risks of nephrectomy and angioembolization were positively associated with patient age, particularly in those 40 years of age and older. Adjusted risk of nephrectomy and angioembolization ranged between ≈ 0.6% and ≈ 1%, and between ≈ 0.3% and ≈ 1% across the patient age range, respectively. Plots depicting marginal effect of age is demonstrated that in patients above 35–40 years of age, a 1-year increase in age is associated with a progressively higher increase in risk of both nephrectomy and angioembolization. The adjusted risk of renorrhaphy did not vary substantially with age and the marginal effect of age was negligible across all ages.Conclusions Older patients with renal trauma are more likely to receive procedural intervention namely nephrectomy and renal angioembolization. These results suggest possible age-related cognitive bias in renal trauma management.
Problematic Social Media Use and Internalizing Symptoms in Adolescents
Authors: Mojtabai Ramin 
Published: April 2023

Abstract
Purpose: This study examined time trends in significant child and adolescent internalizing symptoms and explored the association of excessive and problematic social media use with these symptoms.
Methods: Time trends in internalizing symptoms were assessed using data from five waves of the international survey of Health Behavior in School-aged Children (HBSC), conducted between 2001 and 2018 (N=1,036,869). The associations of frequent and problematic social media use with significant internalizing symptoms were assessed by hierarchical multinomial logistic regression using data from 2001-2002 and the 2017-2018 survey waves. Causal direction between social media use and internalizing symptoms was assessed using linear non-gaussian acyclic models (LiNGAM).
Results: Prevalence of more severe internalizing symptoms increased from 6.7% in 2001-2002 to 10.4% in the 2017-2018 survey waves. The increase was especially large among 15-year old and older girls: from 10.9% to 19.1%. The difference in prevalence of more severe internalizing symptoms across survey waves was fully explained by problematic social media use. LiNGAM analysis confirmed the causal direction of social media use variables with internalizing symptoms.
Conclusions: The study findings suggest that widespread use of social media may explain the increased prevalence of internalizing symptoms in adolescents in recent years.
Towards sustainability: The relationship between foreign direct investment, economic freedom and inclusive green growth
Authors: Ofori Isaac K. , Figari Francesco , Ojong Nathanael 
Published: April 2023

Abstract
This study contributes to the environmental and socioeconomic sustainability literature by examining three important issues. First, the study examines the effects of foreign direct investment (FDI) and economic freedom on inclusive green growth (IGG) in sub-Saharan Africa (SSA). Second, we investigate whether economic freedom interacts with FDI to promote IGG. Third, we identify minimum the thresholds required for economic freedom to cause FDI to foster IGG. The findings are based on macro data for 20 SSA countries. Evidence,based on instrumental variable regression, show that, unconditionally, FDI is not statistically significant for promoting IGG. Second, the study finds that SSA’s ‘Mostly unfree’ economic architecture conditions FDI to reduce IGG. Third, results from our threshold regression reveal that the minimum threshold required for economic freedom to cause FDI to foster IGG is 66.2% (Moderately free). The study sheds new light on investments necessary for SSA’s economic architecture to form relevant synergies with FDI to promote IGG.
JEL Codes: F21; F6; H1; P1; O55; Q01; Q56
Altitudinal differentiation of forest resilience to drought in a dryland mountain
Authors: LI Jie , GAO Xiang , YAN An , CHANG Shuhang , LI Qiuran 
Published: April 2023

Abstract
Drought is the major climate disaster experienced by dryland mountains. However, the altitudinal differentiation of forest resilience to drought and its dominant climate factors in dryland mountains is largely unknown, which is crucial to predict whether the primary forests will collapse under future global warming. In this study, we selected the leaf area index (LAI) and the standardized precipitation evapotranspiration index (SPEI), fitted forest resilience curves based on drought intensity and recovery time, calculated the curve area to define resilience along elevation zones in Qilian Mountains from 1982 to 2020, and analysed the characteristics of resilience altitudinal differentiation and dominant factors. The results showed that the humid characteristics and trends towards humidification in forests were more significant at higher elevations. Forests in the elevation range of 2600–3900 m exhibited faster recovery rates and greater resilience to drought than those in 1700–2600 m. This altitudinal differentiation was related to precipitation non-monotonically. Meanwhile, potential evapotranspiration and cloud cover were the most important climate factors for resilience temporal changes in different altitude zones. The findings of this study confirm the importance of the altitudinal perspective in studies of the dryland mountain evolution under future global change conditions.
HDAC10 negatively regulates NLRP3 inflammasome activation by switching NLRP3 modification from acetylation to ubiquitination
Authors: Yang Min , Qin Zhenzhi , Lin Yueke , Lv Xiaoting , Sun Caiyu , Cheng Yeping , Xuan Haocheng , Cui Xiuling , Ma Wei , Han Lihui 
Published: April 2023

Abstract
The NOD-like receptor protein (NLRP)3 inflammasome is the most extensively studied inflammasome actively involved in various inflammatory diseases, however its regulatory mechanism is not fully understood. Histone deacetylase (HDAC)10 is a member of the class II histone deacetylase, while whether it has any regulatory role in inflammasome activation is not known. Here we demonstrated that HDAC10 directly interacted with NLRP3 and induced the deacetylation of NLRP3, which further resulted in the suppression of NLRP3 protein and inhibition of NLRP3 inflammasome activation. Further investigation revealed that deacetylation of NLRP3 by HDAC10 led to the ubiquitination modification and proteasomal degradation of NLRP3, thus decreased the protein level of NLRP3 and further suppressed its activity. In conclusion, this study suggested an acetylation and ubiquitination switch of NLRP3 induced by HDAC10, which revealed a fine-tuned regulation of NLRP3 inflammasome activation. It also provided a potential therapeutic target for NLRP3 inflammasome-associated diseases and facilitated the development of new immunomodulatory therapeutic strategies for NLRP3 inflammasome involved inflammatory diseases.
Wnt7a can up-regulates cell adhesion related protein fibronectin expression and promotes cell proliferation in corneal epithelial cells
Authors: WU Tengyun , ZHANG Xianxie , LIU Yong , WANG Liqiang , HUANG Yifei 
Published: April 2023

Abstract
Wingless-type MMTV integration site family member 7A (Wnt7a) is known as a ligand for members of the frizzled family receptors (FZDs) that functions in the canonical β-catenin signaling pathway and β-catenin independent pathways and plays an important role in embryonic development and homeostasis maintenance. Herein, we studied whether Wnt7a could promote the corneal epithelium proliferation and the specific mechanisms involved. In this study, expression level and distribution of Wnt7a protein in cornea slices was observed by immunohistochemistry and immunofluorescence assay. Human corneal epithelium cells (HCECs) were cultured in conditioned medium to observe the effect of Wnt7a on cell proliferation. Transcriptome sequencing was performed on the HCECs to analyze the possible role of Wnt7a. We found that, in natural states, Wnt7a protein was mainly concentrated in cells at the base of corneal limbus and a small amount was also distributed in the extracellular matrix of central cornea. After corneal epithelium injury, the expression of Wnt7a in central corneal epithelial cells was significantly increased. Cell wound scratch and CCK-8 assay proved that Wnt7a can promote HCECs proliferation in vitro. The transcriptome sequencing of HCECs cultured in conditional medium showed that Wnt7a could up regulate cell adhesion related genes such as fibronectin, which was verified by western blotting. These results showed that the expression pattern of Wnt7a changed after corneal epithelial injury, and Wnt7a directly participated in the repair after injury by upregulating fibronectin and promoting cell adhesion.
Insulin Resistance may Influence Recurrent Pregnancy Loss and Recurrent Implantation Failure
Authors: Cao Yacong , Ding Miao , Chen Jingbo , Zhang Chaofan , He Fengyi , Li Xiaojia , Jiang Sushi , Zou Yanting , Yang Dongzi , Zhao Xiaomiao 
Published: April 2023

Abstract
Background Recurrent pregnancy loss (RPL) and recurrent implantation failure (RIF) is major and unsolved problems in patients undergoing assisted reproductive technology (ART). The etiology of the two diseases is still inconclusive, and some researchers believe that they are the manifestations of different stages of the same disease, and the etiology is similar. Studies have found that patients with insulin resistance (IR) have an increased risk of miscarriage. This study aimed to explore whether IR plays a role in RPL and RIF.Methods In this retrospective study, we included cases of the clean RPL group, the clean RIF group, the RPL with RIF group, and the control group. The related indexes of blood glucose and insulin in the four groups were compared. The age and waist-to-hip ratio (WHR) were adjusted and further divided into groups according to the times of pregnancy loss and implantation failure.Results There were no significant differences in fasting plasma glucose (FPG) among the four groups. 2hPG in the clean RPL group was significantly higher than that in the control group. Compared to the control group, both the clean RPL group and the RPL with RIF group had significantly higher fasting plasma insulin (FINS), homeostasis model assessment of insulin resistance (HOMA-IR) and homeostasis model assessment of β-cell function (HOMA-β); while the characteristics of the clean RIF group were similar to those of the control group. HOMA-IR in the clean RPL group [2.34(2.18–2.51)] was significantly higher than that in the control group [1.98(1.79–2.16), P < 0.05] and the clean RIF group [1.95(1.77–2.15), P < 0.05]. The incidence of insulin resistance increased linearly with the increase of the times of pregnancy loss (P for trend༜0.001). FINS (P for trend = 0.023), HOMA-IR (P for trend = 0.026), HOMAβ (P for trend = 0.008) shows a trend of rising at first and then decreasing. However, the incidence of IR, FPG, FINS, HOMA-IR, and HOMAβ did not show a linear or quadratic trend with the increased implantation failure.Conclusions In patients undergoing ART, IR may be one of the etiologies of RPL and RIF. With the increase in pregnancy loss times, the function of islet β-cell decreases. While the islet β-cells may be used up in RIF patients.
Improving Image Captioning via Dual-Stream Multi-Layer Dynamic Fusion
Authors: Wang Ronggui , Jia Wenhao , Yang Juan , Xue Lixia 
Published: April 2023

Abstract
Recent researches in image captioning have focused on combining region features and grid features to enhance visual information. However, conventional fusion methods may introduce semantic noise that disturbs model prediction. To address the problem, we propose a simple and efficient dual-stream network, Multi-layer Dynamic Fusion Transformer (MDFT), which employs a multi-layer dynamic fusion method to simultaneously enhance region features and grid features. Specifically, we introduce Cross-layer Perceptual Self-Attention (CPSA) module that locally models visual features at multiple layers to refine visual features. Additionally, we design an Adaptive Selection Controller (ASC) to reduce the computational burden of the layered structure and dynamically select attention layers with similar semantic information for interaction. Through this fusion strategy, MDFT effectively reduces semantic noise and achieves complementary advantages of region features and grid features. The experimental results on the MS-COCO dataset indicate that the MDFT model achieved relatively advanced performance on both local and online test sets, with respective scores of 134.0% and 133.7%.
A combination of nonsolvent and thermally induced phase separation (N-TIPS) technique for the preparation of highly porous cellulose acetate membrane as lithium-ion battery separators
Authors: Arundati Annisaa Hayya , Ratri Christin Rina , Chalid Mochamad , Aqoma Havid , Nugraha Adam F. 
Published: April 2023

Abstract
Polyolefin-based lithium-ion battery separators generally exhibit poor wettability and low porosity, which hamper their ability to preserve electrolyte solution, thus adversely impacting battery performance because it correlates with ionic transport. Therefore, developing a separator with better wettability and porosity has received significant interest in improving battery performance due to its contribution to ionic transport. Herein, porous cellulose acetate (CA) separators were prepared via nonsolvent and thermally induced phase separation (N-TIPS) technique using N-methyl-2-pyrrolidone (NMP) as the polymer solvent and water as the nonsolvent. A glass plate was casted with cellulose acetate dissolved in NMP. Following this, the polymer solution was evaporated at 75°C, then was immersed in a water coagulation bath as the nonsolvent, resulting in a flexible membrane. An evaporation time at 55, 65, or 75 minutes was performed to determine how evaporation affected the structures of membrane pore. CA-based separator that treated with 55 minutes of evaporation generates the highest ionic conductivity of 3.07 x 10 − 2 mS.cm-1, which can be attributed to their uniform microporous structure, porosity of 62%, and electrolyte uptake of 331%. In comparison to Celgard, a commercial polyolefin-based separator that just able to generates an ionic conductivity of 9.41 x 10 − 4 mS.cm-1, the CA 55 membrane exhibits far superior electrochemical performance. Based on these results, the CA 55 membrane is considered a feasible alternative for utilization in lithium-ion battery separators.
Accelerated Algorithms for Silrtc and Halrtcalgorithms by Fast Tri-Factorization Method
Authors: Tavakoli Ali , Ebrahimi Rasool 
Published: April 2023

Abstract
Tensor completion is one of the efficient methods for restoring datasuch that minimizing the rank of the tensor leads to an appropriate solution.However, it gives a non-convex objective function, which generates an NP-hardproblem. To overcome this problem, instead of using the rank function, thetrace norm is applied. To solve this problem, two heuristic algorithms, SimpleLow Rank Tensor Completion (SiLRTC) and High Accuracy Low Rank TensorCompletion (HaLRTC) can be used. In the methods based on trace norm, theSingular Value Decomposition (SVD) is used, which increases computationalcomplexity of these methods with increasing dimensions. In order to reducethe computational complexity of SVD, the method of Fast Tri-Factorization(FTF) can be utilized. In this paper, to accelerate the convergence speed ofSiLRTC and HaLRTC Algorithms, two new combined methods FTF-SiLRTCand FTF-HaLRTC are presented. Additionally, the computational complexityof all algorithms is verified.
2010 Mathematics Subject Classification. Primary 15A18; Secondary 15A69, 74B99.
Dynamic Analysis and Trend Forecast of China's Forestry Carbon Sink Benefits Based on Dual Carbon Targets
Authors: Zhao Sixue , Shi Wei , Qiao Fuwei , An Yi , Wang Weijuan , Zhang Guowei 
Published: April 2023

Abstract

The efficient development of forestry is one of the most effective ways to deal with climate change and achieve carbon neutrality. This paper evaluates and analyzes the benefits of carbon sinks in 31 provinces of China and predicts their future development trends. Firstly, the forest volume expansion method was used to calculate the carbon sink volume and value of Chinese provinces from 2008 to 2018. In addition, the DEA model is used to dynamically analyze input-output efficiency at the provincial and national levels. Lastly, the GM (1, 1) prediction model was used to forecast the trend of China's forestry carbon sink input-output efficiency from 2019 to 2030. It is found that: (1) In terms of space, the benefits of China's forests as carbon sinks are "high in the north and south and low in the east and west," while in terms of time, the differences between regions are getting bigger. (2) Based on efficiency differences, provinces can be categorized into four gradients: high-efficiency, scale-effective, technologically effective, and low-efficiency. The forestry technology level and resource input scale in high-efficiency areas are relatively effective, whereas the indicators above in low-efficiency regions have a significant discrepancy with the optimal level. (3) Predictions indicate that between 2019 and 2030, the benefits of carbon sinks in forests will continue to decline. Based on the findings of this study and the current condition of input-output efficiency, specific recommendations for the long-term development of carbon sinks under the dual carbon objective are provided.
Treatment of a pregnant patient with cardiogenic shock due to bacterial endocarditis combined with Libman-Sacks endocarditis: a case report and literature review
Authors: Chen ZeLun , Wang Tianguang , Zhou Dexing , Wang MingFa 
Published: April 2023

Abstract
Background: As one of the most common cardiac manifestations of systemic lupus erythematous (SLE), Libman-Sacks (LS) endocarditis is a nonbacterial form of thrombotic endocarditis characterized by sterile vegetations deposited on heart valves consisting of fibrin mixed with immune complexes and platelets. Although patients with LS endocarditis usually have no significant valvular disease, persistent LS endocarditis may be complicated by bacterial endocarditis, leading to serious complications, including acute valve regurgitation, acute heart failure, and even cardiogenic shock, which are rare in pregnant patients. Therefore, such patients with atypical SLE manifestations combined with various complications deserve more attention.
Case presentation: We reported a rare case of a pregnant patient without an SLE history who progressed to cardiogenic shock resulting in a preterm birth. After the delivery of the fetus, it was considered that the patient had bacterial endocarditis according to the results of lab tests and echocardiography. LS endocarditis was also found after surgery. Moreover, SLE with catastrophic antiphospholipid syndrome (CAPS) was also confirmed during the course of treatment. Finally, the combined use of methylprednisolone and human immunoglobulin injection was carried out, the patient’s condition improved, and she was discharged on the 13th postoperative day.
Conclusion: The interference of infective endocarditis with the type of preexisting lesion in the disease process can influence our judgment and treatment decisions, which is worth noting.