bluuebunny/crossref_metadata_2025_split huggingface dataset:
Early Life Stress and Body-Mass Index Modulate Brain Connectivity in Alcohol Use Disorder
Authors: Agarwal Khushbu , Joseph Paule , Zhang Rui , Schwandt Melanie , Ramchandani Vijay , Diazgranados Nancy , Goldman David , Momenan Reza 
Published: July 2023

Abstract

Early life stress (ELS) significantly increases susceptibility to alcohol use disorder (AUD) by affecting the interplay between executive and salience networks (SN). The link between AUD and higher body-mass index (BMI) is known, but we lack understanding of how BMI impacts the relationship between ELS and brain connectivity in individuals with AUD. To bridge this gap, we investigated the effects of ELS on brain connectivity in AUD participants, taking into account differences in BMI. The cohort included 401 individuals with AUD, with approximately 60% having a BMI ≥ 25. Within the overall cohort, 123 participants underwent resting-state functional magnetic resonance imaging, revealing intriguing anticorrelations between SN seeds and brain regions involved in somatosensory processing, motor coordination, and executive control as an effect of ELS. Examining the relationship between ELS-driven brain connectivity and BMI, we observed negative correlations in connectivity among low BMI (≤ 24.9) vs. high BMI (≥ 25) individuals. For example, the left supramarginal gyrus (SMG) seed exhibited decreased connectivity with emotion regulation and decision-making regions, including the right occipital cortex, posterior cingulate cortex, and precuneus clusters (all |β| < -0.03, |p| < 0.05). Additionally, the right SMG seed showed reduced connectivity with impulse control and executive function regions, such as the left postcentral/middle frontal gyrus cluster (β = 0.04, p = 0.02). These findings highlight the role of ELS-induced alterations in SN seed connectivity, influenced by BMI, in the neurobiology of AUD. Understanding the neural mechanisms linking obesity, AUD, and ELS can guide targeted interventions for this population.
Conceptual Design of Business Model Canvas Mobile Battery Swap Charging Station
Authors: Rochani Renny , Sutopo Wahyudi , Zakaria Roni , Fahma Fakhrina 
Published: July 2023

The users of electric motorcycle in Indonesia are currently still limited. This is due to three main things, namely the limited amount of energy charging infrastructure, the lack of socialization regarding the knowledge of technical aspects of electric motorcycle and the financing aspects of electric motorcycle ownership. This research develops a conceptual design business model canvas of Mobile Battery Swap Charging Stations (MBSCS) for electric motorcycles which aim to find solutions to the three problems above. The development of the MBSCS model is an alternative to increase the number of electric charging infrastructure quickly, because the advantages of MBSCS include having a higher level of flexibility and simpler installation than Fixed Charging Stations. This research combines the need of increasing infrastructure and improving socialization to the community regarding the advantages of using electric motorcycle through marketing communication media. Increasing the understanding of technical aspects of electric motorcycle is expected to increase people's motivation to adopt electric motorcycle. This research uses secondary data to explore MBSCS business canvas model (BMC), MBSCS ecosystem, and MBSCS prototype design. The analysis illustrates the MBSCS ecosystem that align with the motorcycle users in Indonesia. The existence of MBSCS is expected to significantly increase the buying interest, adoption, and diffusion of electric motors more broadly.
Konfrontasi Islam Ideologis Versi Abdul Qahhar Muzakkar dengan Komunis di Desa Tompo Bulu
Authors: Abdulkahar  , Syamzan Syukur  , Hasaruddin  
Published: July 2023

Abdul Qahhar Mudzakkar merupakan salah satu tokoh yang kini menjadi simbol perjuangan bagi sebagian masyarakat di Sulawesi Selatan. Perjuangannya dalam menyuarakan hak-hak para gerilyawan memberikan kesan tersendiri bagi masyarakat local yang berjuang saat itu. Tidak hanya itu, Qahhar juga menjadi ikon perjuangan bagi para tokoh agama dalam memperjuangkan syariat Islam.
Konflik di tubuh militer dianggap sebagai dasar pemberontakan Qahhar bersama para pasukannya. Padahal jika kita menelaah dari perspektif lain, perjuangan Qahhar tidaklah dilatarbelakangi oleh motif politik; melainkan motif agama. Hal tersebut dapat kita lihat dari berbagai macam rekonsiliasi yang dilakukan oleh tokoh-tokoh pemerintahan namun tak satupun yang berhasil. Ditambah lagi, surat-surat yang ditulis oleh Qahhar benar-benar menampakkan penolakannya terhadap komunis yang telah mendapat ruang khusus di negeri ini.
Hal serupa dapat kita lihat di desa Tompo Bulu yang menjadi salah satu markas berkumpulnya para gerilyawan. Saat itu, ketika PKI datang untuk mencari dukungan, masyarakat lokal menolak dengan alasan PKI-nya. Artinya, masyarakat di pedalaman telah teredukasi sehingga mereka menolak apapun yang berbau PKI dalam kehidupannya.
Sejarah Islam Kedatangan Islam di Dana Mbojo, Bima (TINJAUAN HISTORIS)
Authors: Hamzah Saidin 
Published: July 2023

Penelitian bertujuan untuk merekontruksi sejarah awal masuknya Islam di Dana Mbojo (Bima). Penelitian menggunakan metode sejarah. Untuk mengungkapkan fakta sejarah, penelitian dilaksanakan di Dana Mbojo (Bima) Nusa Tenggara Barat dengan menggunakan beberapa pendekatan: pendekatan historis, antropologi dan sosiologi. Pengumpulan data diperoleh melalui wawancara, observasi dan dokumentasi.Penelitian juga menggunaka studi kepustakaan (library research) melalui data primer dan data sekunder. Data primer diperoleh dari BO’ Sangaji Kai, dokumen dan peninggalan lain yang otentik, sedangkan data sekunder diperoleh dari buku-buku, Jurnal, artikel, skripsi dan tesis. Adapun data yang telah diperoleh diolah dan dianalisis secara mendalam.
Hasil penelitian menunjukan bahwa: Sejarah awal masuknya Islam di Dana Mbojo (Bima) terjadi dalam tiga tahap yakni:1) Terjadinya kontak pertama dengan para pedagang dari Demak. 2) Perantauan dilakukan oleh para pedagang pribumi sehingga sampai ke Ternate dan Tidore. 3) Kedatangan empat utusan dari kerajaan Gowa sampai kepelabuhan Sape dan mengislamkan masyarakat setempat. Peran ulama dan sultan dalam membangun eksistensi Islam di Bima sangatlah besar sehingga meninggalkan bukti dan jejak sejarah seperti Temba Romba bersejarah, Masjid La Kai di Kamina dan langgar kuno di Desa Melayu.
Impliksi dalam penelitian ini, terdapat banyak kekurangan, disebabkan sedikitnya data yang penulis dapatkan.kitab BO’ Sangaji Kai hanya menguraikan secara umum tentang sejarah Bima dan menggunakan bahasa Melayu. Untuk menyingkapi hal demikian data-data yang didapatkan melalui sumber lisah (oral historis).Temba Romba dan masjid Kamina merupakan bukti peninggalan sejarah kehadiran Islam di Bima.maka sangat diharapkan peran pemerintah dalam menjaga dan mengurus (melestarikan) situ-situ sejarah tersebut demi kepentingan masyarakat umum. Karena daerah yang besar adalah daerah yang mampu menghargai warisan leluhurnya.
MELACAK JEJAK ISLAMISASI DI SIDENRENG RAPPANG ABAD 17
Authors: SPI Ahmadyani 
Published: July 2023

Islamisasi di kerajaan Sidenreng, berlangsung pada abad 17 M, di mana raja Sidenreng yang pertama kali menerima agama Islam secara resmi adalah Addatuang Sidenreng La Patiroi Matinroe ri Massepe pada tahun 1018 Hijriyah 1607 Masehi. Setelah Islam datang dan diterima di kerajaan Sidenreng pada masa Addatuang Sidenreng La Patiroi Matinroe ri Massepe, maka dengan resmi Islam menjadi agama resmi kerajaan. Islamisasi di kerajaan Sidenreng mengimplikasikan bahwa Islam adalah agama damai. Islam masuk dan diterima oleh masyarakat kerajaan Sidenreng berlangsung dengan damai yang dilakukan oleh Datuk ri Bandang atas rekomendasi Sultan Alauddin dari Gowa.
PROBLEMATIKA HUKUM PENGAMPUAN DALAM PROSES PERALIHAN HAK ATAS TANAH DAN/ATAU BANGUNAN
Authors: Keumala Dinda , Setiyono Setiyono 
Published: July 2023

Seseorang yang sudah dewasa dapat ditaruh dibawah pengampuan apabila berada dalam keadaan dungu, sakit otak, mata gelap dan boros. Dalam hal demikian, maka orang yang ditaruh dibawah pengampuan memerlukan seorang pengampu untuk dapat bertindak mewakilinya dihadapan hukum. Permasalahan dalam penulisan ini adalah bagaimanakah tatacara peralihan hak atas tanah dan/atau bangunan untuk orang yang ditaruh dibawah pengampuan dan upaya hukum apakah yang dapat dilakukan oleh orang yang ditaruh dibawah pengampuan terhadap adanya peralihan hak atas tanah dan/atau bangunan yang dilakukan oleh pihak pengampu tanpa sepengetahuannya? Tipe penelitian ini adalah normatif, sifat penelitiannya deskriptif, menggunakan data sekunder, analisis data secara kualitatif dan penarikan kesimpulannya menggunakan metode deduktif. Kesimpulannya untuk mengalihkan tanah dan/atau bangunan milik orang yang ditaruh dibawah pengampuan harus ada penetapan pengampuan dan penetapan izin peralihan hak atas tanah dan/atau bangunan dari Pengadilan Negeri dan proses peralihannya harus dilakukan dihadapan PPAT yang berwenang. Sedangkan upaya hukum yang dapat dilakukan orang yang ditaruh dibawah pengampuan adalah mengajukan upaya pembatalan terhadap penetapan pengampuan kepada Mahkamah Agung dan mengajukan gugatan pembatalan akta-akta peralihan hak atas tanah dan/atau bangunan yang telah dibuat kepada Pengadilan Negeri serta mengajukan pembatalan sertipikat kepada Pengadilan Tata Usaha Negara (PTUN)
Sex differences in alpha-synucleinopathies: a systematic review
Authors: Raheel Kausar , Deegan Gemma , Di Giulio Irene , Cash Diana , Ilic Katarina , Gnoni Valentina , Chaudhuri K. Ray , Drakatos Panagis , Moran Rosalyn , Rosenzweig Ivana 
Published: July 2023

BackgroundPast research indicates a higher prevalence, incidence, and severe clinical manifestations of alpha-synucleinopathies in men, leading to a suggestion of neuroprotective properties of female sex hormones (especially estrogen). The potential pathomechanisms of any such effect on alpha-synucleinopathies, however, are far from understood. With that aim, we undertook to systematically review, and to critically assess, contemporary evidence on sex and gender differences in alpha-synucleinopathies using a bench-to-bedside approach.MethodsIn this systematic review, studies investigating sex and gender differences in alpha-synucleinopathies (Rapid Eye Movement (REM) Behavior Disorder (RBD), Parkinson’s Disease (PD), Dementia with Lewy Bodies (DLB), Multiple System Atrophy (MSA)) from 2012 to 2022 were identified using electronic database searches of PubMed, Embase and Ovid.ResultsOne hundred sixty-two studies were included; 5 RBD, 6 MSA, 20 DLB and 131 PD studies. Overall, there is conclusive evidence to suggest sex-and gender-specific manifestation in demographics, biomarkers, genetics, clinical features, interventions, and quality of life in alpha-synucleinopathies. Only limited data exists on the effects of distinct sex hormones, with majority of studies concentrating on estrogen and its speculated neuroprotective effects.ConclusionFuture studies disentangling the underlying sex-specific mechanisms of alpha-synucleinopathies are urgently needed in order to enable novel sex-specific therapeutics.
GENOTYPING OF A NEW TYPE OF "ADUCHI" OF THE KALMYK BREED BY THE GENES DGAT1, GHR, IGF-1, PIT-1
Authors: ТРЕТЬЯКОВА Р.Ф. , КАЮМОВ Ф.Г. 
Published: July 2023

Изучена структура популяции создаваемого типа калмыцкого скота Адучи по полиморфизму генов DGAT1, GHR, IGF-1, PIT-1. В результате исследования животных создаваемого типа по локусу гена DGAT1 большая часть их оказалась носителями генотипа КК (72%), меньшая — генотипа КА (28%). Отмечается также полное отсутствие среди изучаемых особей генотипа АА. При исследовании стада по гену GHR установлено наибольшее количество особей (64%) с генотипом YY. Гомозиготные варианты (ВВ) с аллелем В гена IGF-1 встречались в 1,5 раза чаще, чем гетерозиготные генотипы (АВ). В целом по стаду отмечается высокая встречаемость В-аллеля (0,72) в локусе IGF-1 гена и низкая — А-аллеля (0,28). Частота встречаемости В-аллеля гена PIT-1 оказалась выше, чем у А-аллеля, на 30%. Проведенный опыт позволил оценить генетическую структуру создаваемого мясного типа Адучи на основе взаимодействия наследственности калмыцкого скота и животных абердин ангусской породы американской селекции.
The structure of the population of the created type of Kalmyk cattle Aduchi was studied by the polymorphism of the genes DGAT1, GHR, IGF-1, PIT-1. As a result of the study of animals of the type being created by the DGAT1 gene locus, omost of them turned out to be carriers of the CC genotype (72%), a smaller one of the KA genotype (28%). There is also a complete absence of the AA genotype among the studied individuals. When studying the herd by the GHR gene, the largest number of individuals (64%) with the YY genotype was found. Homozygous variants (BB) with the allele B of the IGF-1 gene were 1.5 times more common than heterozygous genotypes (AB). In general, the herd has a high occurrence of the B-allele (0.72) at the IGF-1 gene locus and a low occurrence of the A-allele (0.28). The frequency of occurrence of the B-allele of the PIT-1 gene was 30% higher than that of the A-allele. The conducted experience allowed us to evaluate the genetic structure of the created meat type of Aduchi based on the interaction of the heredity of Kalmyk cattle and animals of the Aberdeen Angus breed of American breeding.
Effect of nursing guidelines on quality of life, and treatment satisfaction among patients with hypothyroidism
Authors: Deif Hala I. Abo , El-Naby Amel G.A. 
Published: July 2023

Background
Many patients with hypothyroidism still experience greater reduction in quality of life (QoL) and treatment satisfaction when on the recommended replacement dosage. Thus, nursing guidelines could improve patients’ knowledge, QoL, and treatment satisfaction among patients with hypothyroidism.

Aim
To evaluate the effect of nursing guidelines on knowledge, QoL, and treatment satisfaction among patients with hypothyroidism.

Design
A quasi-experimental pre–posttest control group design was used.

Setting
The study was conducted at endocrinology outpatient clinics in one of the teaching hospitals at Cairo University.

Sample
A convenient sample of 60 adult male and female patients diagnosed with primary hypothyroidism on a stable dose of levothyroxine was included.

Tools
Four tools were used to collect data pertinent to the study: (a) personal data form. It consists of two parts: (i) demographic data, including age, sex, education level, and place of residence, and (ii) medical data related to comorbid diseases and BMI; (b) Patients’ Hypothyroidism Knowledge Assessment Questionnaire; (c) Thyroid Patient-reported Quality-of-Life Questionnaire (ThyPRO39); and (d) Hypothyroid Treatment Satisfaction Questionnaire (ThyTSQ).

Results
There were no statistically significant differences between the study and control groups before application of nursing guidelines regarding demographic and medical variables as well as the total mean scores of patients’ knowledge about hypothyroidism, QoL, and treatment satisfaction. However, highly statistically significant differences were found between both groups at 1 and 2 months after implementation of nursing guidelines concerning patients’ knowledge about hypothyroidism, QoL, and treatment satisfaction (P=0.000 and 0.000, respectively).

Conclusion
Nursing guidelines could improve patients’ knowledge and QoL among patients with hypothyroidism by taking these nursing guidelines fully into account alongside the recommended treatment where nursing guidelines cover all suspected hypothyroid disease and thereby to improve knowledge, QoL, and treatment satisfaction. Recommendations: this study recommends that nurses provide verbal and written nursing guidelines for patients with hypothyroidism in both inpatient and outpatient clinics.
Pattern of weight gain during pregnancy among pregnant women attending antenatal clinics
Authors: Aboelsoud Wedad H. , Ghonemy Gehan E. , Ashour Ahmed S.A. , Aboushady Reda M.N. 
Published: July 2023

Background
Excessive and inadequate weight gain during pregnancy is associated with adverse maternal and neonatal outcomes. The aim of this study was to assess the pattern of weight gain among pregnant women attending antenatal clinics.

Design
A descriptive research design was adopted to describe how weight pattern changes during pregnancy.

Sample
A convenience sample of 400 pregnant women was included in the study.

Setting
The study was conducted at the antenatal outpatient clinic of El-Kasr El Aini University Hospital, Cairo University, Egypt.

Tools
Two tools were used: (a) maternal structured interviewing and (b) assessment and follow-up.

Results
Approximately 36% had normal weight, 34.3% were overweight, 26% were obese, and only 3.8% were underweight at recruitment. Appropriate weight gain was observed in 81.0% of underweight pregnant women and 75.5% of normal weight women. However, 61.5% of overweight women and 72% of obese women gained weight above the recommendation range by the Institute of Medicine. The mean total weight gain at the time of delivery among underweight women was 13.5 kg, normal weight women was 12.43 kg, overweight women was 12.05 kg, and obese women was 10.43 kg.

Conclusion
Overweight and obese women had excessive weight gain during pregnancy, whereas underweight and normal weight women gained weight within the Institute of Medicine recommendations.

Recommendation
Counseling during early pregnancy toward adequate gestational weight gain management should be required for pregnant women at the outpatient clinic.
Strategies Des Resiliences Urbaines Face A La Production Des Services De Base En Eau Potable, Electricite Et Assainissement Dans Les Quartiers Batumona A Kimbanseke Et Talangay A N’sele/Rd.Congo
Authors: EZINGA Odon KINSWEKI , IMWANGANA Fils MAKANZU 
Published: July 2023

La réflexion sur la problématique des résiliences urbaines liées à l’approvisionnement en eau potable, électricité et assainissement dans les quartiers BATUMONA à Kimbanseke et TALANGAY à N’sele est basée sur le fait que la périurbanisation rapide des pays en voie de développement est liée à une consommation excessive de la ressource foncière pour l’habitat BEAUGARD & HALLEUX, (2015) ; ANGEL & ali,(2016).Le concept de résilience urbaine paraît savant et, est très mal connu par les sujets enquêtés. Cette situation se justifie probablement par le niveau très bas d’instruction des sujets enquêtés dû à l’insuffisance de moyens financiers, au faible revenu (salaires toxiques), dont le dénominateur commun est la précarité de conditions de vie de la population et leurs conséquences néfastes TREFON, (2O11), MABIN, BUTCHER & BLOCH, (2013) ; ANGEL & ali, (2016). Il s’agit là, d’une conséquence de l’urbanisation rapide et de la répulsion du centre-ville, en raison de la forte pression foncière, de coûts élevés de la vie pour les ménages à faible revenu à Kinshasa en général et en particulier dans l’aire d’étude à Kinshasa-Est. Il y a lieu de faire également référence à l’inexistence de politique de planification urbaine WATSON, (2009), BINZANGI & FALANKA, (2014).Globalement, l’aire d’étude fait face à une croissance extraordinaire de son contenant et doit être gérée rationnellement, pour assurer sa durabilité environnementale. Malheureusement, l’état actuel des sites étudiés est confronté à des précarités à outrance des conditions de vie urbaine. Cette précarité a engendré la pauvreté urbaine de masse qui a ouvert la voie aux vulnérabilités des conditions de vie urbaine et celles des habitants. Face à la crise économique persistante, les sujets enquêtés ont développé d’autres stratégies de survies appelées « résiliences urbaines ». Les sujets enquêtés éprouvent de difficultés énormes de tous ordres qui constituent des conditions majeures de viabilité et vivabilité environnementales urbaines. Ces difficultés constituent des facteurs limitant de possibilités de la plupart des ménages enquêtés dans l’aire d’étude, à prévenir les risques environnementaux et leurs aléas sur les vies humaines. A ce titre, les difficultés précitées soustraient l’aire d’étude des exigences de durabilité environnementale urbaine.
A GAMIFICAÇÃO COMO PRÁTICA DE ENSINO INOVADORA: UM OLHAR PARA AS TEORIAS EPISTEMOLÓGICAS
Authors: Curvo Evaleis Fátima , Mello Geison Jader , Leão Marcelo Franco 
Published: July 2023

A gamificação consiste na utilização de mecanismos e sistemáticas de jogos para motivar e engajar o participante tornando-o protagonista. Essa pesquisa tem como objetivo refletir sobre as teorias epistemológicas que se relacionam e influenciam na metodologia ativa da gamificação. A pesquisa possui uma abordagem qualitativa e bibliogáfica, de caracter exploratório e descritivo. A metodologia adotada para a coleta de dados foi a revisão de artigos, livros e dissertações e no banco de dados da CAPES, do Google Acadêmico e do Scielo. O intuito realizar uma reflexão sobre as teorias epistemológicas que se relacionam e influenciam na metodologia ativa da gamificação, para que seja possível contribuir com aprendizagem do estudante, tornando as aulas mais prazerosas e significativas. No que se refere a área cientifica, verificamos que a tecnologia sempre fez parte do nosso cotidiano, até os dia atuais. Portanto, acreditamos ser possivél articular as estratégias de ensino com a gamificação, com as teorias epistemologos, favorecendo, assim, a aprendizagem dos estudantes.
Resonant solutions for elliptic systems with Neumann boundary conditions
Authors: Delgado Briceyda B. , Pardo Rosa 
Published: July 2023

We consider a sublinear perturbation of an elliptic eigenvalue system with homogeneous Neumann boundary conditions. For oscillatory nonlinearities and using bifurcation from infinity, we prove the existence of an unbounded sequence of turning points and an unbounded sequence of resonant solutions.
See also https://ejde.math.txstate.edu/special/02/d1/abstr.html
Kompetensi Guru Pendidikan Agama Katolik (Pak) Di Era Milenial Dan Pengaruhnya Terhadap Peningkatan Motivasi Belajar Siswa
Authors: Haru Emanuel 
Published: July 2023

Being a teacher in the millenial era is not an easy profession to run. He/ She has to fulfil many demands. He/ She is challenged to have various competencies. Among those that must be fulfilled are competence in technology part. A teacher in the millenial era must be master in using technology tools,such as computer and internet. At least, a teacher must know to operate basic computer programs. By this way, a learning will take place interesting and effectively. For example, a teacher must be able to present His/ Her subject with power point. Besides, a teacher must be able to use e-mail and several other internet programs which are important to support the learning process. By mastering technology, a teacher is expected to explore many sources of knowledge. Therefore, He/ She hasmore knowledge better than students. In addition, a teacher must also prove his professionalism as a teacher by perform all four competencies namely pedagogical, personal, social and professional competencies.
A Catholic Religious Education Teacher must also have such competencies. Apart from those mentioned, one of the typical competencies possessed by Catholic Religious Education Teachers is spiritual competence. By having the competencies as mentioned above, a teacher (including Catholic Religious Education Teachers) is able to increase students’ learning motivation in the entire of learning process in a school.
In this article, the writer presents several studies that prove the influence of the competencies of a teacher (including Catholic Religious Education Teacher) on student learning motivation, especially in this millennial era. These studies concluded that the higher competency of a teacher, cause the students have a good motivation in learning. In contrary, the lower competence of a teacher cause the lower motivation of students to learn.For this reason, the Catholic Religious Education Teacher is expected to be able to apply these competencies in the daily learning process so that students’ learning motivation increases and in the end, the students’ learning achievements also increase.