bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Study of Motor Functional Asymmetry Indicators in Different Sportsmanship Level Esports Athletes
Authors: Рiatysotska Svitlana , Podrіgalo Leonid , Romanenko Vyacheslav , Yefremenko Andrii , Petrenko Yuliia , Poltoratska Hanna 
Published: August 2023

Purpose. to research and analyze of the indicators of functional asymmetry in different sportsmanship level esports athletes.
Methods. the study involved 20 middle-aged athletes (18±1.53) years old, divided into groups according to their sportsmanship. Group 1: elite players of semi-professional teams in CS:GO and DOTA 2 disciplines, n=10, age (19.2±0.50) years. Group 2: amateur CS:GO and DOTA 2 players, n=10, age (18.2±1.04) years. The functional asymmetry of the movements of the upper limbs was determined using a special program for tablet computers running iOS, developed at the departments of martial arts, computer science and biomechanics of the KhSAPC.
Results. It has been established that in terms of the number of clicks per unit of time, elite esports athletes are dominated by amateurs by 5.54% on the left and 5.14% on the right hand; in terms of visual motor reaction time, elite esports athletes prevail by 5.54% on the left hand and 5,07% on the right hand; elite esports athletes showed a 13.3% shorter left-hand click duration, but amateurs showed a 6,83% shorter right-hand click duration.
Conclusions. Players with a higher level of preparedness tend to have less asymmetrical movements. In the proposed test, elite athletes demonstrate a greater number of movements per unit of time; at the 2nd stage of testing, the differences are significant (p<0.05). At the same time, the reaction time of more skilled players is less than that of amateurs; at the 2nd and 4th stages of the test, the differences are significant (p<0.05). Indicators of functional asymmetry of movements of the upper limbs informatively characterize the level of preparedness of esports athletes and can be included in the program for monitoring the physical condition of players in cybersport.
The 28 October 2022 Mw 3.8 Goesan Earthquake Sequence in Central Korea: Stress Drop, Aftershock Triggering, and Fault Interaction
Authors: Kim Won-Young , Seo Min-Seong , Park Jun Yong , Han Sangwoo , Son Young Oh , Kim YoungHee 
Published: August 2023

ABSTRACT
We identified the causative fault of the 2022 Goesan, Korea, earthquake sequence based on the precise relocation of the sequence that revealed a 0.8 km-long fault plane striking east-southeast–west-northwest. The fault plane encompasses the largest foreshock, the mainshock, and the majority of the aftershocks. The orientation of the fault plane is consistent with the left-lateral strike-slip motion along the east-southeast (106°) striking nodal plane of the focal mechanism. The Jogok fault system recently mapped in the source area runs through the mainshock epicenter with a consistent strike and left-lateral strike-slip motion, which suggests that it is the likely causative fault of the 2022 Mw 3.8 Goesan earthquake sequence. It is a rare case of assigning a causative fault for a small-sized (Mw 3.8) earthquake with some confidence in a typical stable continental region setting, albeit no surface break observed due to deep focal depth (~13 km) and the small size of the event. Aftershocks on the main fault plane, and on the adjacent subparallel fault patches seemed to be triggered by the increase in Coulomb stress caused by the mainshock. Two large aftershocks on the subparallel fault patches show slightly higher stress drops than the large foreshock and mainshock on the main fault plane, likely due to high frictional strength on those fault patches. Events of the 2022 Goesan earthquake sequence progressed rapidly in time and appear to be high stress-drop events compared with other earthquakes that occurred in other regions in Korea, probably due to the long quiescent period in the Goesan earthquake epicentral region.
Public health interventions in the control of emerging diseases
Authors: Bhattacharyya Himashree , Agarwalla Rashmi 
Published: August 2023

There has been an unprecedented increase in the burden of emerging diseases in the recent past. This has been attributed to changes in environment, human behavior, increased travel and human intrusion into the sylvatic cycle which has facilitated the emergence of novel and resistant strains of pathogens. A public health intervention is any effort or policy that is designed to improve mental and physical health of the population. This article focusses on the various public health interventions like vaccination, nutritional intervention, hygiene and sanitation, health awareness which has been and can contribute immensely to curb the rising threat of emerging diseases. Much research has been going on regarding the vaccines against new emerging diseases like SARS-CoV, Ebola, Lassa fever, Nipah, Chikungunya and Rift valley fever. Nutritional interventions has proven to be of much benefit in low and middle income countries because of its synergistic effect with infections. Quarantine and sanitation measures were highly effective strategies for control of COVID-19 pandemic. These preventive interventions along with a robust public health infrastructure can serve as an effective barrier in the spread of many emerging strains of diseases.
Treatment with Dielectric Barrier Discharge (DBD) plasma restricts Aspergillus niger growth isolated from wheat grain
Authors: Al-Khafaji Thikra K. 
Published: August 2023

Microbiological contamination by fungi impacts the quality and safety of wheat grain storage. This study aimed to evaluate the efficacy of cold plasma in restricting the growth of the fungus, Aspergillus niger, which was isolated from wheat grains. A dielectric barrier discharge (DBD) operating at atmospheric pressure generated cold plasma that was used to treat the fungus, and the impact of this treatment was investigated at various periods 1, 2, 4, 6, and 15 minutes. The results revealed a highly significant decrease in the growth and number of spores of Aspergillus niger compared to the controls. This study revealed an efficient technique for enhancing wheat grain storage that could be a foundation for further large-scale studies.
Future flow and water temperature scenarios in an impounded drainage basin: Implications for summer flow and temperature management downstream of the dam
Authors: Khorsandi Mostafa , St-Hilaire Andre , Arsenault Richard , Martel Jean-Luc , Larabi Samah , Schnorbus Markus , Zwiers Francis 
Published: August 2023

Abstract
Water temperature is a key variable affecting fish habitat in rivers. The Sockeye salmon (Oncorhynchus nerka), a keystone species in north western aquatic ecosystems of North America, is profoundly affected by thermal regime changes in rivers, and it holds a pivotal role in ecological and economic contexts due to its life history, extensive distribution and commercial fishery. In this study, we explore the effects of climate change on the thermal regime of the Nechako River (British Columbia, Canada), a relatively large river partially controlled by the Skins Lake Spillway. The CEQUEAU hydrological-thermal model was calibrated using discharge and water temperature observations. The model was forced using the Fifth generation of ECMWF Atmospheric Reanalysis data for the past and meteorological projections (downscaled and bias-corrected) from climate models for future scenarios. Hydrological calibration was completed for the 1980–2019 period using data from two hydrometric stations, and water temperature calibration was implemented using observations for 2005–2019 from eight water temperature stations. Changes in water temperature were assessed for two future periods (2040–2069 and 2070–2099) using eight Coupled Model Intercomparison Project Phase 6 climate models and using two Shared Socioeconomic Pathway scenarios (4.5 and 8.5 W/m2 by 2100) for each period. Results show that water temperatures above 20°C [an upper threshold for adequate thermal habitat for Sockeye salmon migration in this river] at the Vanderhoof station will increase in daily frequency. While the frequency of occurrence of this phenomenon is 1% (0–9 days/summer) based on 2005–2019 observations, this number range is 3.8–36% (0–62 days/summer) according to the ensemble of climate change scenarios. These results show the decreasing habitat availability for Sockeye salmon due to climate change and the importance of water management in addressing this issue.
Silver Diamine Fluoride with Sodium Fluoride Varnish versus Silver Diamine Fluoride in arresting early childhood caries: A randomized field trial
Authors: Abdellatif Enas.B , Tantawi Maha El , Elkashlan Mona K 
Published: August 2023

Abstract
Background
Early childhood caries (ECC) is the most prevalent chronic health problem in young children, and it can be arrested using professionally applied fluoride such as Sodium fluoride (NaF) varnish and Silver Diamine Fluoride (SDF). This trial compared two interventions to arrest ECC lesions: 38% SDF combined with 5% NaF varnish versus 38% SDF and assessed whether the arrest rate was affected by baseline lesion severity measured by ICDAS.
Methods
Children aged ≤ 4 years from 4 nurseries in a rural area in Alexandria, Egypt joined the study in March 2022. They were included if they had at least one active carious lesion with ICDAS codes ≥ 3. They were randomized to receive either 38% SDF with 5% NaF varnish or 38% SDF at baseline and after 6 months and 5% NaF varnish was re-applied after 3 months. The primary outcome was lesion arrest status after six months. Parents’ satisfaction with their children’s appearance was the secondary outcome. Pearson Chi-Square test was used for bivariate comparison and multi-level multiple logistic regression was used to assess the effect of the intervention on caries arrest controlling for confounders. The interaction between the intervention and baseline lesion severity (categorized into moderate and severe lesions) was assessed and the p value was calculated.
Results
The study included 1606 lesions in 220 children, median (IQR) age = 48(9) months. The percentages of arrested lesions after the application of SDF + NaF and SDF only were 77.7% and 73.2% (p = 0.035). In multivariable analysis, SDF + NaF had significantly greater caries arrest effect than SDF alone (AOR = 2.12, p = 0.03) with significant difference (p = 0.03) between moderate (AOR = 4.10, p = 0.005) and advanced (AOR = 1.92, p = 0.08) lesions. Most parents were satisfied with their children’s appearance with no significant difference between groups (SDF + NaF = 84.5%, SDF = 78.18%, p = 0.23).
Conclusion
SDF + NaF had a higher arrest rate than SDF alone and this difference was observed in moderate but not advanced lesions. The findings have implications for the non-invasive management of ECC.
Trial registration
This trial was registered in the clinicaltrials.gov registry (#NCT05642494) on 8/12/2022.
Effect of physiotherapeutic procedures on the bioelectric activity of the masseter muscle and the range of motion of the temporomandibular joints in the female population with chronic pain: a randomized controlled trial.
Authors: Gębska Magdalena , Dalewski Bartosz , Pałka Łukasz , Kiczmer Paweł , Kołodziej Łukasz 
Published: August 2023

Abstract
Introduction: Physical therapy (PT) methods applied in dentistry are increasingly discussed nowadays. Taking into account a rapidly growing number of temporomandibular disorder (TMD) and orofacial pain patients, it is reasonable to determine which of the available physiotherapeutic (PT) methods are more effective than others, especially in terms of their possible analgesic and myorelaxant effects. Objective: To assess manual and physical factors influencing pain reduction or elimination and increased muscle tension in patients with TMDs; yet the influence of the applied forms of PT on the range of motion (ROM) of temporomandibular joints (TMJs). Material and Methods: A randomized, parallel-group, RCT, single-blind, equi-randomized (1:1) study was conducted in DC/TMD Group Ib patients (20–45 years of age). An experimental group (G1, n = 104) and a control group without TMD (G2, n = 104) were created according to CONSORT guidelines. Diagnostic measurements were performed in both groups (mass sEMG, temporomandibular joint range of motion-ROM, pain intensity - NRS). Group G1 was randomly divided (envelope method) into 4 therapeutic groups, in which therapy was carried out for 10 days: magnetostimulation (MS), magnetoledotherapy (MLE), magnetolaserotherapy (MLA), manual therapy (MT). Each time after the therapy, ROM and NRS measurements were performed, and after the 5th and 10th day EMG. Results: Statistically significant differences were found in the sEMG values of the masseter muscles, TMJ ROM and the pain intensity in G1 and G2 (p < 0.00). The largest decrease in sEMG (% MVC) of the masseter muscle occurred in the subgroup in which the manual therapy (MT) procedures were applied, p < 0.000. There was no clinically significant difference in and between other subgroups. There was a distinct mandible ROM increase noted in the MT group, with minimal changes in the MLA and MLE groups and no changes in the MS group. There was a clear increase in the lateral mobility of both right and left TMJ in the MT group. There were no differences in the course of the study in the MS group, and slight increases in the MLA and MLE groups. In the case of pain measurements, the greatest decrease in pain intensity was observed in the MT subgroup. Conclusions: According to our results manual therapy is an effective form of treatment in patients with pain, increased masticatory muscle tension and limitation in mandible ROM. Dental physiotherapy should become an integral part of multimodal TMD patients’ treatment.
Elevated Serum γ-glutamyl Transferase of First Trimester Predicts Preterm Birth among Pregnant Women: A Retrospective Cohort Study in China
Authors: He Zhen , Sun Yin , Shi Xuezhong , He Yuan , Liangkun Ma , Yongli Yang , Chen Qinzheng , Jia Xiaocan , Yang Xuanjin , Wang Yaxin , Liu Nana , Zhang Suhan 
Published: August 2023

Abstract
Background Abnormal liver function indicators during pregnancy may be independent risk factors for preterm birth (PTB). However, the relationship between liver function indicators in the first trimester and PTB was not clearly understood. This study aimed to assess whether these indicators in the first trimester could predict subsequent risk of PTB.
Methods From July 1, 2020, to June 30, 2022, a retrospective cohort study was conducted including 5,567 pregnant women who gave birth at Peking Union Medical College Hospital, China. We collected liver function indicators (ALB, albumin; ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; γ-GT, γ-glutamyl transferase), and clinical history and demographic information from pregnant women and their infants. Multivariate logistic regression models were used to estimate aOR (adjusted odds ratios) and 95% CIs (confidence intervals).
Results PTB incidence was 6.4% (275/5,152) in this cohort. The highest quartile of γ-glutamyl transferase (γ-GT) was associated with an increased risk of PTB compared to the lowest quartile [aOR 1.47(95% CI 1.02~2.14]), after adjusting for confounding factors.Other individual liver function indicators (ALB, ALP, ALT and AST) were not significantly associated with PTB. The association with PTB was found among female infant in higher concentrations of γ-GT.
Conclusions During the first trimester, higher concentrations of γ-GT, but not other liver function indicators, were significantly associated with an increased risk of PTB among Chinese pregnancy women.
Delay of diagnosis in autism spectrum disorder and its influencing factors
Authors: Zhu Feng-lei , Ji Yue , Wang Lu , Zhu Hui-lin , Xu Min , Ji Yan , Zou Xiao-bing 
Published: August 2023

Abstract
Background
Although experienced clinicians are capable of diagnosing autism spectrum disorders (ASD) in children before they reach the age of 2, the average age of diagnosis reported internationally is between 4 and 5 years, indicating a significant delay in diagnosis. The objective of this study was to determine the factors influencing the diagnosis delay time (DDT) in children with ASD and to shorten the diagnosis period.
Methods
We employed the Cox proportional hazard model to examine the effects of individual, family, sociodemographic, and healthcare system indicators on DDT in a retrospective survey involving ASD children and their families.
Results
This study included a total of 560 subjects. The findings revealed that the median DDT in children with ASD was 8.16 (15.99) months, and the mean DDT was 13.68 (17.11) months. Language development level of children (RR = 0.521, 95%CI 0.400 ~ 0.680, P < 0.001), enrollment in school (RR = 1.950, 95%CI 1.552 ~ 2.450, P = < 0.001), experience of previous misdiagnosis (RR = 1.637, 95%CI 1.249 ~ 2.146, P < 0.001), degree of caregiver's concern about initial symptoms (RR = 0.781, 95%CI 0.635 ~ 0.960, P = 0.019), and whether the initial symptom is a core defect of ASD (RR = 1.758, 95%CI 1.210 ~ 2.553, P = 0.003) were identified as independent risk factors for delayed diagnosis of ASD in children under the age of six.
Conclusions
In China, there is a significant delay in the diagnosis of ASD among children. Children at risk of delayed ASD diagnosis include those with normal language abilities and early-onset non-autistic core difficulties, whose parents neglect their children’s atypical symptoms, those who have already started school, and those with a history of misdiagnosis. We urge parents, educators, and healthcare providers to closely monitor atypical child development during early childhood, enhance growth monitoring for preschool and school-aged children, and be attentive to children with normal language skills.
Novel Triangular Anchor Reduction Forceps versus Towel Forceps for Long Oblique or Spiral Distal Tibial Fractures: A Comparative Study
Authors: Li Tao , Wu Zhonghan , Wang Jingkun , Tang Yuntao , Xu Xinzhong 
Published: August 2023

Abstract
Objective: To compare the efficacy of triangular anchor repositioning forceps and scarf forceps in the treatment of long oblique or spiral distal tibial fractures with intramedullary nailing.
Methods: Finally, 58 patients were included. According to the intraoperative repositioning method, they were divided into the scarf clamp repositioning group (n=26) and the triangular anchor repositioning group (n=32). The operative time, a number of intraoperative fluoroscopies, intraoperative bleeding, quality of postoperative fracture reduction, length of hospital stay, fracture healing time, American orthopedic foot and ankle society (AOFAS) score, efficacy and complications at the last follow-up were compared between the two groups.
Results: All patients participated in more than 1 year of follow-up. ①There were no significant differences in the composition ratios of age, sex, underlying disease, and mechanism of injury between the two groups; ②The operating time and intraoperative fluoroscopy number of patients in the triangular anchor reduction group were significantly lower than those in the scarf clamp reduction group (P<0.05), while the quality of fracture reduction was higher than that in the scarf clamp reduction group (P<0.05), and the differences in the remaining perioperative indexes were not significant; ③Patients in the triangular anchor reduction group had shorter postoperative fracture healing time and better ankle function than those in the scarf clamp reduction group (P<0.05); ④Patients in the two groups had various There was no significant difference in the incidence of various complications between the two groups, but the overall complication rate was significantly lower in the triangular anchor reduction group (P<0.05).
Conclusion: The use of triangular anchor repositioning forceps can improve the quality of fracture repositioning, shorten fracture healing time, reduce the occurrence of complications, reduce the operative time and the number of intraoperative fluoroscopies, and no significant increase in local infection was observed, which is an effective and reliable repositioning method.
Causal relationship of gastroesophageal reflux disease with chronic periodontitis: A bidirectional Mendelian randomization study
Authors: Zheng Shuhao , Zhuo Qunhao , Liu Yi , Xie Jiarong , Sun Fang , Xu Lei 
Published: August 2023

Abstract
Background: Some observational studies have demonstrated an association between gastroesophageal reflux disease(GERD) and chronic periodontitis. We used a Mendelian randomization (MR) analysis to evaluate the bidirectional association between GERD and chronic periodontitis.
Materials and Methods: We collected data from two genome-wide association studies (GWAS) of individuals of European ancestry. During the meta-analysis, the relationship between the two variables was estimated primarily using the inverse weighted method (IVW). A sensitivity analysis was performed using Cochran's Q test, leave-one-out test and MR pleiotropy residual sum and outlier analysis (MR- PRESSO).
Results: GERD was causally related tochronic periodontitis risk (OR = 1.270, 95% confidence interval (CI): 1.040-1.550, P=0.019). However, no causal effect of chronic periodontitis on GERD was found (OR=1.006, 95% confidence interval (CI): 0.991-1.022, P=0.435).
Conclusion: According to this MR study, the outcomes supported GERD on therisk of chronic periodontitis, but according to the analysis, there is no evidence for chronic periodontitis on GERD risk.
Botulinum Toxin Type A: Efficacy and Safety Profile in the Treatment of Lower Limb Spasticity in Children with genetic Disorders
Authors: Saleh Dina Amin , Farouk Nermine , Korkar George H , Sabry Tamer M , Mahmoud Mohamed Ashraf , Ali Mohamed , Awad Ahmed Abdellatif , Hamdi Hussein , Ghany Walid Abdel , elsayed Ahmed M. 
Published: August 2023

Abstract
Background: Botulinum toxin type A (BTX-A) is a well-established therapeutic modality for the treatment of lower limb spasticity in children with cerebral palsy. There is paucity of evidence about its effectiveness and safety in genetic disorders.
Objective: To assess the functional outcomes and safety of BTX-A injection for the treatment of lower limb spasticity in children with genetic disorders.
Methods: We conducted a retrospective chart review for history, demographic data, comorbidities, neurological examination, and neuroimaging findings for all patients diagnosed with genetic disorders from December 2020 to December 2022 in Ain Shams university hospital database. Outcome assessment were the Gross Motor Function Classification system (GMFCS) for Cerebral Palsy "Initially and after 6 months' post-treatment", the Modified Ashworth scale (MAS) "initially and at 1,3,6 month post-treatment" and the achieved preset functional goals using the Goal Attainment Scaling (GAS) at 4-6 months post-treatment.
Results:
A total of 90% of the patients showed improvement in their GAS scores, 20% achieving the preset goal, 55% achieving a better outcome than anticipated and 15% achieving the best possible outcome. Furthermore, the GMFCS and MAS scores showed a significant statistical improvement after six months post-injection (p=0.02, p=0.03), respectively. None of the patients developed serious adverse effects except a child diagnosed with mitochondrial cytopathy.
Conclusion:
BTX-A injections were effective and showed a high safety profile in children with genetic disorders. To our knowledge, this is the first study that specifically targets this patient population, filling a gap in the literature and providing valuable insights into the potential benefits of BTX-A injections for this group. However, further large-scale studies are recommended to confirm these findings.