bluuebunny/crossref_metadata_2025_split huggingface dataset:
The PSZ-MCMF catalogue of Planck clusters over the DES region
Authors: Hernández-Lang D , Klein M , Mohr J J , Grandis S , Melin J-B , Tarrío P , Arnaud M , Pratt G W , Abbott T M C , Aguena M , Alves O , Andrade-Oliveira F , Bacon D , Bertin E , Brooks D , Burke D L , Carnero Rosell A , Carrasco Kind M , Carretero J , Castander F J , Costanzi M , da Costa L N , Pereira M E S , Desai S , Diehl H T , Doel P , Everett S , Ferrero I , Flaugher B , Frieman J , García-Bellido J , Gruen D , Gruendl R A , Gschwend J , Gutierrez G , Hinton S R , Hollowood D L , Honscheid K , James D J , Kuehn K , Kuropatkin N , Lahav O , Lidman C , Melchior P , Mena-Fernández J , Menanteau F , Miquel R , Palmese A , Paz-Chinchón F , Pieres A , Plazas Malagón A A , Raveri M , Rodriguez-Monroy M , Romer A K , Scarpine V , Sevilla-Noarbe I , Smith M , Suchyta E , Tarle G , Thomas D , Weaverdyck N ,   (DES Collaboration)
Published: August 2023

ABSTRACT
We present the first systematic follow-up of Planck Sunyaev–Zeldovich effect (SZE) selected candidates down to signal-to-noise (S/N) of 3 over the 5000 deg2 covered by the Dark Energy Survey. Using the MCMF cluster confirmation algorithm, we identify optical counterparts, determine photometric redshifts, and richnesses and assign a parameter, fcont, that reflects the probability that each SZE-optical pairing represents a random superposition of physically unassociated systems rather than a real cluster. The new PSZ-MCMF cluster catalogue consists of 853 MCMF confirmed clusters and has a purity of 90 per cent. We present the properties of subsamples of the PSZ-MCMF catalogue that have purities ranging from 90 per cent to 97.5 per cent, depending on the adopted fcont threshold. Halo mass estimates M500, redshifts, richnesses, and optical centres are presented for all PSZ-MCMF clusters. The PSZ-MCMF catalogue adds 589 previously unknown Planck identified clusters over the DES footprint and provides redshifts for an additional 50 previously published Planck-selected clusters with S/N&gt;4.5. Using the subsample with spectroscopic redshifts, we demonstrate excellent cluster photo-z performance with an RMS scatter in Δz/(1 + z) of 0.47 per cent. Our MCMF based analysis allows us to infer the contamination fraction of the initial S/N&gt;3 Planck-selected candidate list, which is ∼50 per cent. We present a method of estimating the completeness of the PSZ-MCMF cluster sample. In comparison to the previously published Planck cluster catalogues, this new S/N&gt;3 MCMF confirmed cluster catalogue populates the lower mass regime at all redshifts and includes clusters up to z∼1.3.
Testing the cosmological principle with CatWISE quasars: a bayesian analysis of the number-count dipole
Authors: Dam Lawrence , Lewis Geraint F , Brewer Brendon J 
Published: August 2023

ABSTRACT
The Cosmological Principle, that the Universe is homogeneous and isotropic on sufficiently large scales, underpins the standard model of cosmology. However, a recent analysis of 1.36 million infrared-selected quasars has identified a significant tension in the amplitude of the number-count dipole compared to that derived from the cosmic microwave background (CMB), thus challenging the Cosmological Principle. Here, we present a Bayesian analysis of the same quasar sample, testing various hypotheses using the Bayesian evidence. We find unambiguous evidence for the presence of a dipole in the distribution of quasars with a direction that is consistent with the dipole identified in the CMB. However, the amplitude of the dipole is found to be 2.7 times larger than that expected from the conventional kinematic explanation of the CMB dipole, with a statistical significance of 5.7σ. To compare these results with theoretical expectations, we sharpen the ΛCDM predictions for the probability distribution of the amplitude, taking into account a number of observational and theoretical systematics. In particular, we show that the presence of the Galactic plane mask causes a considerable loss of dipole signal due to a leakage of power into higher multipoles, exacerbating the discrepancy in the amplitude. By contrast, we show using probabilistic arguments that the source evolution of quasars improves the discrepancy, but only mildly so. These results support the original findings of an anomalously large quasar dipole, independent of the statistical methodology used.
Assessing the Feasibility of Conducting Smoking Cessation Outreach in Food Pantries: A Pilot Intervention Study
Authors: Kim-Mozeleski Jin E , Smell Adrianna , Castele Madeline C , Ogden Erin , Trapl Erika S 
Published: August 2023

Abstract

Introduction
Smoking prevalence is high among US adults with food insecurity. This study examined how food assistance settings, namely food pantries, can serve as a community-based venue to reach food insecure adults who smoke for smoking cessation.

Methods
Partnering with a local hunger relief organization, we conducted surveys and focus groups of food pantry clients in Greater Cleveland, Ohio, followed by food pantry-based outreach events to connect people who smoke to the Ohio Tobacco Quit Line.

Results
The survey included 132 participants who visited a food pantry (M age = 47; 74% women; 39% Black/African American), of whom 35% were using tobacco and 31% were smoking cigarettes. Among those currently smoking (M cigarettes/day = 9), 76% intended to quit in the next 6 months, and 82% had not used nor heard of the quitline. Informed by focus group themes, we conducted a total of 22 outreach events at four pantries. Among those interested in smoking cessation resources from the outreach events (n = 54), 78% were able to be subsequently contacted. Of them, 74% provided consent for quitline referral. The remainder either declined or were unable to participate.

Conclusions
While it was feasible to leverage food pantries for smoking cessation outreach, the overall reach was low. Despite high interest in quitting, there was limited effectiveness of outreach efforts without adaptations to each pantry setting and in recognition of the immediate food needs and with challenges related to the COVID-19 pandemic. There remains a critical need to address high rates of smoking among populations experiencing food insecurity.

Implications
Tobacco cessation services are increasingly recognizing the need to address food insecurity and other social needs that commonly occur in populations who use tobacco at higher rates. This research underscores both the value and the challenges related to leveraging food pantries as a community-based venue for smoking cessation outreach. In addition to improvements in outreach models, long-term investments in structural interventions are also needed to address underlying poverty and socioeconomic disadvantage that ultimately drive disparities in smoking and in food insecurity.
Successful Treatment of Paecilomyces variotii Pneumonia and Lupus Nephritis With Posaconazole-Cyclophosphamide Co-administration Without Drug Interaction–Induced Toxicity
Authors: Pechacek Joseph , Webb Taura , Ferré Elise M N , Schmitt Monica M , DiMaggio Thomas , Kobrin Dale , Rajasimhan Suraj , Colton Ben , Lewis Russell E , Andes David , Herrera Alejandro , Hammoud Dima , Seyedmousavi Seyedmojtaba , Hasni Sarfaraz , Bolaños Jonathan , Afzali Behdad , Lionakis Michail S 
Published: August 2023

Abstract
Paecilomyces variotii is an opportunistic mold that causes pulmonary infections in immunosuppressed humans that are often treated with triazole therapy. Lupus nephritis is a major cause of progressive kidney disease in patients with systemic lupus erythematosus, often requiring cyclophosphamide-based therapies. Triazole-cyclophosphamide co-administration is challenging as triazoles increase cyclophosphamide concentrations, which can worsen cyclophosphamide toxicity. We describe herein a patient with Paecilomyces variotii pneumonia and concomitant lupus nephritis who was successfully treated with posaconazole and echinocandin-bridged interruptions to allow for cyclophosphamide therapy. This regimen was well-tolerated without cyclophosphamide toxicity and achieved improvements in both fungal pneumonia and renal function.
Pharmacovigilance Study on Eosinophilic Pneumonia Induced by Anti-MRSA Agents: Analysis Based on the FDA Adverse Event Reporting System
Authors: Okada Naoto , Niimura Takahiro , Saisyo Atsuyuki , Kawaguchi Yoshitaka , Ishizawa Keisuke , Kitahara Takashi 
Published: August 2023

Abstract

Background
Eosinophilic pneumonia (EP) is a rare adverse event caused by several types of drugs, such as antibiotics; however, its characteristics remain poorly described. This study aimed to analyze the disproportionality between the occurrence of EP and anti–methicillin-resistant Staphylococcus aureus (anti-MRSA) agents and to characterize anti-MRSA agent–induced EP events using the Food and Drug Administration Adverse Event Reporting System (FAERS).

Method
Disproportionality linking EP and anti-MRSA agents was analyzed through bayesian confidence propagation neural networks of information components and reporting odds ratio methodologies. The FAERS data set for the fourth quarter of 2012 to the fourth quarter of 2022 was used. We also analyzed the characteristics of EP induced by anti-MRSA agents.

Results
A total of 14 805 795 reports were obtained from FAERS. Disproportionality analysis revealed that the EP signal was detected only in cases with the administration of daptomycin (DAP). This disproportionality signal was consistently detected in the sensitivity analysis. When compared with other reports of DAP-related adverse events, the reports of DAP-related EP were characterized by male sex (odds ratio [OR], 1.94; 95% CI, 1.12–3.37), older age (&gt;70 years; OR, 2.70; 95% CI, 1.68–4.33), and longer duration of treatment (&gt;21 days; OR, 5.08; 95% CI, 3.21–8.05).

Conclusions
This study revealed that among the anti-MRSA agents, disproportionality in the occurrence of EP was observed only with DAP. Our results suggest that sex, age, and treatment duration may affect the occurrence of DAP-induced EP. Clinicians should exercise caution regarding EP during DAP administration.
Reappraising Crystallization Kinetics with Overgrowth Chronometry: an in Situ Study of Olivine Growth Velocities
Authors: Welsch Benoît , Faure François , First Emily C 
Published: August 2023

Abstract
We investigated the early stages of olivine crystal growth via in situ seeded experiments in a single plagioclase-hosted melt inclusion, using a heating stage microscope. Each experiment was subjected to a cooling ramp of 7800°C/h followed by an isothermal dwell at 19°C, 38°C, 57°C, 77°C, 96°C or 129°C of undercooling. The seeds (6–16 μm in diameter Ø) grew into large crystals (Ø 80–169 μm) in 3 to 30 min through the symmetrical development of tabular, skeletal, and dendritic overgrowths as the undercooling of the system increased. Time-resolved image processing and incremental measurements of the overgrowth thicknesses indicate up to three stages of crystal growth: an acceleration stage, a linear (constant growth rate) stage, and a deceleration stage. At the isotherm, the growth velocities reach a stable maximum that in all experiments corresponds to the period of linear growth. The highest linear values are measured at the $\left\{101\right\}$ interfaces, from 2.1 × 10−8 m/s at 19°C of undercooling to 4.8 × 10−7 m/s at 129°C of undercooling. Crystal growth is slower at other interfaces, in the ranges 1.9–7.6 × 10−8 m/s and 4.5 × 10−9 – 7.6 × 10−8 m/s for the $\left\{100\right\}$ and $\left\{001\right\}$ forms, respectively. Growth in the $&lt;010&gt;$ dimension appears limited to less than 2.4 × 10−8 m/s at 129°C of undercooling. We constrain the uncertainty on these growth velocities, which includes the environmental conditions (± 8.6°C on the nominal undercooling) and the measurements of crystal lengths (underestimated by &lt;16% at most fast interfaces).
A systematic and comprehensive review of 19 pre-existing datasets indicates that our linear growth velocities are faster than most growth rates determined at comparable undercoolings. Growth rates determined as half crystal lengths divided by total time are intrinsically low estimates of the true maximum, linear growth velocities, because the total time includes periods of slower or non-growth, and measured crystal dimensions are subject to projection foreshortening or truncation. These errors can lead to values that are several times to several orders of magnitude lower than the true maximum growth rates. This study completes and refines previously published data on the crystallization kinetics of olivine, highlighting the sensitivity of growth rates to specific environmental conditions and measurement methods. We emphasize the importance of symmetrical growth and true maximum growth velocities for interpreting olivine growth histories.
What Went Right? South African Democracy and the Study of Political Science
Authors: Holmes Carolyn E 
Published: August 2023

Abstract
South Africa has been an important case in both scholarship and the public eye for decades. The anti-apartheid struggle saw mass international participation, and there was significant international optimism about the South African transition to multiracial democracy in 1994. Yet in the years since the advent of the new democratic dispensation in South Africa, a kind of pessimism has set in about the prospects for the country and for its democracy. Into this conversation Evan Lieberman's book, Until We Have Won Our Liberty, inserts a new perspective, arguing that South African democracy has been remarkably successful. Relying on a largely descriptive analysis of progress in infrastructure, rights guarantees, and dignified development, Lieberman argues that democratic performance in the country, especially given the starting point for democracy, has exceeded reasonable expectations. Lieberman's focus on what has gone right in South African democracy bucks many disciplinary and scholarly norms but presents a compelling argument for introspection on the part of the field.
Co-design and its consequences: developing a shared patient engagement framework in the IMI-PARADIGM project
Authors: Gunn Callum J , Fruytier Sevgi E , Finlay Teresa , Vat Lidewij Eva , Zuiderent-Jerak Teun , Schuitmaker-Warnaar Tjerk Jan 
Published: August 2023

AbstractWhilst patient engagement (PE) activities have become increasingly prevalent in development of medicines, collaborating actors have different perspectives on the goals of PE and its added value. In the production of PE standards and frameworks, the significance of these differences tends to be minimised. Boundary objects have been shown to mediate knowledge exchange between multiple social worlds, thereby playing an important role in participatory technology governance processes. In this article, we draw on boundary objects to learn from the process of co-designing a PE monitoring and evaluation (M&E) framework within the Innovative Medicines Initiative–Patients Active in Research and Dialogues for an Improved Generation of Medicines (IMI-PARADIGM) consortium (2018–20). As facilitators of PARADIGM’s co-design process, we report on the challenges encountered in developing a practicable M&E framework that serves a variety of needs and interests. We argue these challenges of co-design reflect a negotiation of different frames throughout, thereby providing insight into how such work may contribute to addressing the challenge of knowledge integration in institutional medicines development settings.
Protocol for a randomized controlled study examining the role of rapid eye movement sleep in fear-related mechanisms: rapid eye movement fragmentation and fear inhibition in adults with insomnia disorders before and after cognitive behavioral therapy for insomnia
Authors: Vuong Vivien , Mellor Alix , Risbrough Victoria B , Bei Bei , Drummond Sean P A 
Published: August 2023

Abstract
Insomnia confers a 2.5-to-3-fold risk of developing posttraumatic stress disorder (PTSD) after a traumatic event. The mechanism underlying this increased risk, however, remains unknown. We postulate insomnia may contribute to PTSD by disrupting rapid eye movement (REM) sleep, as REM sleep disruption has been shown to impair fear inhibitory processes, which are central to the natural recovery from trauma. To test this hypothesis, the following protocol aims to: (1) examine the relationship between REM sleep and fear inhibition in insomnia, and (2) examine whether reducing REM fragmentation by treating insomnia, in turn, improves fear inhibition. Ninety-two adults with Insomnia Disorder will be block randomized (1:1; stratified by sex) to an active treatment (7 weekly sessions of Cognitive Behavioral Therapy for Insomnia (CBT-I) via telehealth) or waitlist control condition. REM sleep (latent variable derived from REM %, REM efficiency, and REM latency) and fear inhibition (i.e. safety signal and extinction recall) will be assessed pre- and post-treatment in a 4 night/3 day testing protocol via at-home polysomnography and the fear-potentiated startle paradigm, respectively. Fear extinction recall will serve as the primary outcome, while safety signal recall will serve as the secondary outcome. In summary, this study aims to test an underlying mechanism potentially explaining why insomnia greatly increases PTSD risk, while demonstrating an existing clinical intervention (CBT-I) can be used to improve this mechanism. Findings will have potential clinical implications for novel approaches in the prevention, early intervention, and treatment of PTSD.
Variation in Isolate Virulence and Accession Resistance Associated with Diaporthe aspalathi, D. caulivora, and D. longicolla in Soybean
Authors: Mohan Karthika , Kontz Brian , Okello Paul , Allen Tom W. , Bergstrom Gary C. , Bissonnette Kaitlyn , Bonkowski John , Bradley Carl A. , Buck James , Chilvers Martin I. , Dorrance Anne , Giesler Loren , Kelly Heather , Koehler Alyssa , Lopez-Nicora Horacio D. , Mangel Dylan , Markell Samuel G. , Mueller Daren , Price III Paul P. , Rojas Alejandro , Shires Madalyn , Smith Damon , Spurlock Terry , Webster Richard W. , Wise Kiersten , Yabwalo Dalitso , Mathew Febina M. 
Published: August 2023

Important stem and grain diseases of soybean ( Glycine max [L.] Merr.) caused by Diaporthe aspalathi, D. caulivora, and D. longicolla reduce yield in the United States. Sources of resistance to these pathogens have previously been reported; however, there is limited information regarding their resistance when exposed to geographically distinct isolates of the same species. In this study, four accessions from the USDA Soybean Germplasm Collection with reported resistance to D. aspalathi, D. caulivora, or D. longicolla were evaluated using geographically representative isolates within each species from the United States. For each fungus, a greenhouse experiment was conducted as a completely randomized design with a factorial arrangement (isolate × accession). Plants were inoculated at the second to third trifoliate growth stage using toothpicks infested with isolates of each Diaporthe species. Pathogenicity was assessed 21 days postinoculation as 0 = no lesion, 0.5 = lesion length > 1 cm, and 1 = dead plant. A significant isolate-by-accession interaction ( P < 0.05) was observed to affect pathogenicity as analyzed using nonparametric statistics (relative treatment effects [RTEs]), indicating that accessions responded differently to the isolates. Correlation analyses suggested that the RTEs on ‘Tracy-M’, ‘Dowling’, and ‘Crockett’ were weakly to moderately correlated with those of the D. aspalathi-susceptible ‘Bragg’, as well as for ‘PI567473B’ and ‘Century’ ( D. caulivora), and ‘PI417507’ ( D. longicolla), with the RTEs on ‘Hawkeye’ ( P > 0.05) indicating possible genetic variation for resistance within these accessions. Our results provide information related to the resistance of previously identified accessions to develop commercial cultivars with resistance to important pathogens within the genus Diaporthe. [Formula: see text] Copyright © 2023 The Author(s). This is an open access article distributed under the CC BY 4.0 International license .
Healing Peristomal Wounds Around Retracted Stomas with Negative-Pressure Wound Therapy: A Case Series
Authors: Cwaliński Jarosław , Hermann Jacek , Banasiewicz Tomasz 
Published: August 2023

ABSTRACT
One method for treating a retracted stoma is a vacuum dressing that cleans the wound and protects against intestinal leakage. This case series describes the use of an integrated, single-use negative-pressure wound therapy (NPWT) dressing to treat retracted stomas as an alternative to other noninvasive remedies. The report includes seven patients who were hospitalized in the authors’ surgical department from 2019 to 2020. All patients developed severe peristomal infection that failed to respond to local treatment with proper ostomy appliances or specialist dressings. After cleaning each wound and removing necrotic lesions, the authors applied a single-use hydrofiber NPWT dressing to each patient. The dressing was changed every 2 to 5 days, depending on the effects of the therapy. The stoma orifice was covered with a bag with two-piece ostomy systems. The peristomal wound healed in all cases, and leakage was eliminated. The mean time of treatment was 14 days (range, 10–21 days), and the vacuum dressings were changed an average of four times (range, 3–7 times). None of the patients required a stoma translocation or other additional surgery. Three patients received systemic IV antibiotic therapy to treat general infection. Single-use NPWT dressings protect peristomal wounds from bowel leakage and do not hinder the application of stoma bags. This system, similar to standard NPWT devices, effectively protects infected stomas from retraction.
Mesenchymal Stem Cells and Regenerative Therapy with Bilateral Gracilis Flaps for Perineal Reconstruction of a Wound Infection in the Setting of Anal Squamous Cell Carcinoma
Authors: Garcia Matthew F. , Tiwari Kirti K. , Gendreau Julian L. , Burgess Pamela L. , Taupin Philippe , Martin Eric D. 
Published: August 2023

ABSTRACT
Many patients are affected by HIV/AIDS, and these conditions are highly prevalent worldwide. Patients with HIV/AIDS can experience debilitating wound infections that often require flap reconstruction and become challenging for surgeons to treat. In the past 5 years, mesenchymal stem cells have been tested and used as regenerative therapy to promote the growth of tissues throughout the body because of their ability to successfully promote cellular mitogenesis. To the authors’ knowledge, the use of mesenchymal stem cell grafting following necrosis of a myocutaneous gracilis flap (as part of perineal wound reconstruction) has never been reported in the literature.
In addition, the use of mesenchymal stem cells and regenerative medicine combined in the setting of squamous cell carcinoma of the anus with prior radiation (along with comorbid AIDS) has not been previously documented.
In this report, the authors outline the case of a 60-year-old patient who had a recipient bed (perineum) complication from prior radiation therapy. Complicating the clinical picture, the patient also developed a Pseudomonal organ space infection of the pelvis leading to the failure of a vertical rectus abdominis myocutaneous flap and myocutaneous gracilis flaps. As a result, the patient underwent serial operative debridements for source control, with the application of mesenchymal stem cells, fetal bovine dermis, porcine urinary bladder xenograft, and other regenerative medicine products, achieving a highly successful clinical outcome. A procedural description for future use and replication of this method is provided.