bluuebunny/crossref_metadata_2025_split huggingface dataset:
Construction of 2D/3D/2D‐Structured Perovskite for High‐Performance and Stable Solar Cells
Authors: Zhang Yiqing , Zhang Yingzhu , Niu Benfang , Huang Yanchun , Wu Haotian , Fu Weifei , Chen Hongzheng 
Published: September 2023

Abstract2D/3D‐structured perovskites are promising for high‐performance and stable solar cells due to the passivation ability and hydrophobic character of the large organic cations. However, most of the 2D/3D‐structured perovskites prepared by adding ammonium halides into the precursors or depositing ammonium halides on top of a 3D perovskite film ignore the buried interface which is crucial for the device efficiency and stability. Here, 2D/3D/2D‐structured perovskite films with optimized buried interface are constructed by depositing phenethylammonium bromide (PEABr) on top and 2D perovskite PEA2FA2Pb3Br10 at the bottom of 3D Cs0.07FA0.85MA0.08Pb(I0.95Br0.05)3 perovskite. Thus, a power conversion efficiency (PCE) of 24.2% is achieved due to the minimal nonradiative recombination. The encapsulated device also shows an improved stability, maintaining 93.5% of the initial value after 1000 h under 1 sun equivalent illumination at the maximum power point. This strategy may provide important insights into designing perovskite film structures to achieve high‐performance solar cells with high stability.
Achieving 17.46% Efficiency CsPbI2Br Perovskite Solar Cells via Multifunction Lead Chloride‐Modified ZnO Electron Transporting Layer
Authors: Li Yaru , Zhang Yong , Zhu Peide , Li Jingbai , Wu Jiawen , Zhang Jiyao , Zhou Xianyong , Jiang Zhengyan , Wang Xingzhu , Xu Baomin 
Published: September 2023

AbstractCsPbI2Br perovskite solar cells (PSCs) have garnered significant attention owing to their remarkable thermal stability and desirable bandgap. However, CsPbI2Br‐based devices still face critical challenges, particularly at the interfaces between the active layer and adjacent components. In this study, a multifunctional ZnO composition has developed as the electron transporting layer (ETL) for CsPbI2Br PSCs, enabling simultaneous efficient charge extraction and passivation of buried interface defects in CsPbI2Br. The nanocomposite, composed of PbCl2‐modified ZnO (PbCl2‐ZnO), facilitates the regulation of bandgap and conduction band to align the energy level of ETL and CsPbI2Br. Additionally, the residual PbCl2 at the buried interface of the perovskite incorporates into the perovskite lattice, reducing I defect and thus improving film quality. The improved energy level alignment at the ETL/CsPbI2Br interface and the suppressed I defect‐induced carrier nonradiative recombination result in a remarkable reduction in energy loss from 0.73 to 0.52 eV. Finally, the PbCl2‐ZnO hybrid nanocomposite ETL significantly enhances the efficiency of CsPbI2Br PSCs, increasing it from 14.15% to 17.46%, representing one of the highest reported power conversion efficiency (PCE) values for CsPbI2Br PSCs. These findings demonstrate the potential of PbCl2‐ZnO hybrid nanocomposite as an effective ETL for CsPbI2Br PSCs.
Catalyzing Generation and Stabilization of Oxygen Vacancies on CeO2−x Nanorods by Pt Nanoclusters as Nanozymes for Catalytic Therapy
Authors: Zhang Jiankang , Yang Yu , Qin Fengmin , Hu Tingting , Zhao Xinshuo , Zhao Shichao , Cao Yueqiang , Gao Zhe , Zhou Zhan , Liang Ruizheng , Tan Chaoliang , Qin Yong 
Published: September 2023

AbstractAlthough CeO2 nanomaterials have been widely explored as nanozymes for catalytic therapy, they still suffer from relatively low activities. Herein, the catalyzing generation and stabilization of oxygen vacancies on CeO2 nanorods by Pt nanoclusters via H2 gas reduction under mild temperature (350 °C) to obtain Pt/CeO2−x, which can serve as a highly efficient nanozyme for catalytic cancer therapy, is reported. The deposited Pt on CeO2 by the atomic layer deposition technique not only can serve as the catalyst to generate oxygen vacancies under mild temperature reduction through the hydrogen spillover effect, but also can stabilize the generated oxygen vacancies. Meanwhile, the oxygen vacancies also provide anchoring sites for Pt forming strong metal‐support interactions and thus preventing their agglomerations. Importantly, the Pt/CeO2−x reduced at 350 °C (Pt/CeO2−x‐350R) exhibits excellent enzyme‐mimicking catalytic activity for generation of reactive oxygen species (e.g., ·OH) as compared to other control samples, including CeO2, Pt/CeO2, and Pt/CeO2−x reduced at other temperatures, thus achieving excellent performance for tumor‐specific catalytic therapy to efficiently eliminate cancer cells in vitro and ablate tumors in vivo. The excellent enzyme‐mimicking catalytic activity of Pt/CeO2−x‐350R originates from the good catalytic activities of oxygen vacancy‐rich CeO2−x and Pt nanoclusters.
Suppressing Rampant and Vertical Deposition of Cathode Intermediate Product via PH Regulation Toward Large‐Capacity and High‐Durability Zn//MnO2 Batteries
Authors: Chen Minfeng , Yang Ming , Han Xiang , Chen Jizhang , Zhang Peixin , Wong Ching‐Ping 
Published: September 2023

AbstractDespite great prospects, Zn//MnO2 batteries suffer from rampant and vertical deposition of zinc sulfate hydroxide (ZSH) at the cathode surface, which leads to a significant impact on their electrochemical performance. This phenomenon is primarily due to the drastic increase in the electrolyte pH value upon discharging, which is closely associated with the electrodissolution of Mn‐based active materials. Herein, the pH value change is effectively inhibited by employing an electrolyte additive with excellent pH buffering capability. As such, the formation of ZSH at the cathode is postponed, resulting in the deposition of ZSH in a horizontal arrangement. This strategy can significantly enhance the utilization efficiency of cathode active material, while also enabling a solid electrolyte interphase layer at the Zn anode to address low Zn stripping/plating reversibility. With the optimal electrolyte, the Zn//MnO2 battery realizes a 25.6% increase in the specific capacity at 0.2 A g−1 compared to that with the baseline electrolyte, great rate capability (161.6 mAh g−1 at 5 A g−1), and superior capacity retention (90.2% over 5,000 cycles). In addition, the pH buffering strategy is highly applicable in hydrogel electrolytes. This work underscores the importance of pH regulation for Zn//MnO2 batteries and provides enlightening insights.
Aramid Nanodielectrics for Ultraconformal Transparent Electronic Skins
Authors: Zhao Sanchuan , Zhao Yingtao , Li Chenning , Wang Wei , Liu Hai‐Yang , Cui Lei , Li Xiang , Yang Zhenhua , Zhang Anni , Wang Yurou , Lin Yuxuan , Hao Tailang , Yin Jun , Kang Joohoon , Zhu Jian 
Published: September 2023

AbstractOn‐skin electronics require minimal thicknesses and decent transparency for conformal contact, imperceptible wearing, and visual aesthetics. It is challenging to search for advanced ultrathin dielectrics capable of supporting the active components while maintaining bending softness, easy handling, and wafer‐scale processability. Here, self‐delaminated aramid nanodielectrics (ANDs) are demonstrated, enabling any skin‐like electronics easily exfoliated from the processing substrates after complicated nanofabrication. In addition, ANDs are mechanically strong, chemically and thermally stable, transparent and breathable, therefore are ideal substrates for soft electronics. As demonstrated, compliant epidermal electrodes comprising silver nanowires and ANDs can successfully record high‐quality electromyogram signals with low motion artifacts and satisfying sweat and water resistance. Furthermore, ANDs can serve as both substrates and dielectrics in single‐walled carbon nanotube field‐effect transistors (FETs) with a merely 160‐nm thickness, which can be operated within 4 V with on/off ratios of 1.4 ± 0.5 × 105, mobilities of 39.9 ± 2.2 cm2 V−1 s−1, and negligible hysteresis. The ultraconformal FETs can function properly when wrapped around human hair without any degradation in performance.
Boron and Nitrogen Isotope Effects on Hexagonal Boron Nitride Properties
Authors: Janzen Eli , Schutte Hannah , Plo Juliette , Rousseau Adrien , Michel Thierry , Desrat Wilfried , Valvin Pierre , Jacques Vincent , Cassabois Guillaume , Gil Bernard , Edgar James H. 
Published: September 2023

AbstractThe unique physical, mechanical, chemical, optical, and electronic properties of hexagonal boron nitride (hBN) make it a promising 2D material for electronic, optoelectronic, nanophotonic, and quantum devices. Here, the changes in hBN's properties induced by isotopic purification in both boron and nitrogen are reported. Previous studies on isotopically pure hBN have focused on purifying the boron isotope concentration in hBN from its natural concentration (≈20 at% 10B, 80 at% 11B) while using naturally abundant nitrogen (99.6 at% 14N, 0.4 at% 15N), that is, almost pure 14N. In this study, the class of isotopically purified hBN crystals to 15N is extended. Crystals in the four configurations, namely h10B14N, h11B14N, h10B15N, and h11B15N, are grown by the metal flux method using boron and nitrogen single isotope (> 99%) enriched sources, with nickel plus chromium as the solvent. In‐depth Raman and photoluminescence spectroscopies demonstrate the high quality of the monoisotopic hBN crystals with vibrational and optical properties of the 15N‐purified crystals at the state‐of‐the‐art of currently available 14N‐purified hBN. The growth of high‐quality h10B14N, h11B14N, h10B15N, and h11B15N opens exciting perspectives for thermal conductivity control in heat management, as well as for advanced functionalities in quantum technologies.
Thermochromic Printable and Multicolor Polymeric Composite Based on Hybrid Organic–Inorganic Perovskite
Authors: Cinquino Marco , Prontera Carmela Tania , Giuri Antonella , Pugliese Marco , Giannuzzi Roberto , Maggiore Antonio , Altamura Davide , Mariano Fabrizio , Gigli Giuseppe , Esposito Corcione Carola , Giannini Cinzia , Rizzo Aurora , De Marco Luisa , Maiorano Vincenzo 
Published: September 2023

AbstractHybrid organic–inorganic perovskites (PVKs) are among the most promising materials for optoelectronic applications thanks to their outstanding photophysical properties and easy synthesis. Herein, a new PVK‐based thermochromic composite is demonstrated. It can reversibly switch from a transparent state (transmittance > 80%) at room temperature to a colored state (transmittance < 10%) at high temperature, with very fast kinetics, taking only a few seconds to go from the bleached to the colored state (and vice versa). X‐ray diffraction, Fourier‐transform infrared spectroscopy, differential scanning calometry, rheological, and optical measurements carried out during heating/cooling cycles reveal that thermochromism in the material is based on a reversible process of PVK disassembly/assembly mediated by intercalating polymeric chains, through the formation and breaking of hydrogen bonds between polymer and perovskite. Therefore, differently from other thermochromic perovskites, that generally work with the adsorption/desorption of volatile molecules, the system is able to perform several heating/cooling cycles regardless of environmental conditions. The color and transition temperature (from 70 to 120 °C) can be tuned depending on the type of perovskite. Moreover, this thermochromic material is printable and can be deposited by cheap techniques, paving the way for a new class of smart coatings with an unprecedented range of colors.
Lab‐in‐a‐Bead: Magnetic Janus Bead Probe for the Detection of Biomarkers in Blood
Authors: Gunatilake Udara Bimendra , Caballe‐Abalos Adriana , Garcia‐Rey Sandra , Mercader‐Ruiz Jon , Basabe‐Desmonts Lourdes , Benito‐Lopez Fernando 
Published: September 2023

AbstractRemotely handled miniaturized colorimetric sensor platforms with multiple functionalities are able to mimic conventional laboratory operations with reduced assets. The integration of a magnetic phase in a miniaturized hydrogel sensor system allows the manipulation of the sensor, under a magnetic field, in a programmable manner. However, dark color interferences from conventional magnetic phases (Fe3O4, Fe2O3, and Fe micro/nanoparticles) affect the signal readout, hindering the colorimetric response. Therefore, a novel Janus bead configuration is introduced and tested by the localized incorporation of ferromagnetic iron microparticles into a TiO2 nanotubes/alginate hydrogel bead biosystem, under an applied magnetic field. The so‐called hydrogel Janus bead shows both, magnetic translocation and biosensing properties in the same bead. These beads are used for the direct colorimetric analysis of biomarkers in blood. The surface of the Janus bead prevents the biofouling of red blood cells, keeping the sensor surface clean for accurate optical colorimetric analysis. Moreover, the external magnetic manipulation of the bead permits precise control of the time and position of the bead in the sample. Therefore, multiple functionalities are presented by a single magnetic TiO2 nanotubes/alginate Janus bead such as actuation, low biofouling, and sensing, positioning this technology as a truly Lab‐in‐a‐Bead System.
Anti Stokes Thermometry of Plasmonic Nanoparticle Arrays
Authors: Ezendam Simone , Nan Lin , Violi Ianina L. , Maier Stefan A. , Cortés Emiliano , Baffou Guillaume , Gargiulo Julian 
Published: September 2023

AbstractMetallic nanoparticles possess strong photothermal responses, especially when illuminated as ensembles due to collective effects. However, accurately quantifying the temperature increase remains a significant challenge, impeding progress in several applications. Anti Stokes thermometry offers a promising solution by enabling direct and non‐invasive temperature measurements of the metal without the need for labeling or prior calibration. While Anti Stokes thermometry is successfully applied to individual nanoparticles, its potential to study light‐to‐heat conversion with plasmonic ensembles remains unexplored. In this study, the theoretical framework and the conditions that must be fulfilled for applying Anti Stokes thermometry to ensembles of nanoparticles are discussed. Then, this technique is implemented to measure the light‐induced heating of square arrays of Au nanodisks. The obtained temperature measurements are validated using wavefront microscopy, demonstrating excellent agreement between the two thermometry methods. These results showcase the extension of Anti Stokes thermometry to plasmonic ensembles, highlighting its potential for implementation in the diverse photothermal applications involving these systems.
Early Endosomes Undergo Calcium‐Triggered Exocytosis and Enable Repair of Diffuse and Focal Plasma Membrane Injury
Authors: Bittel Daniel C. , Jaiswal Jyoti K. 
Published: September 2023

AbstractCells are routinely exposed to agents that cause plasma membrane (PM) injury. While pore‐forming toxins (PFTs), and chemicals cause nanoscale holes dispersed throughout the PM, mechanical trauma causes focal lesions in the PM. To examine if these distinct injuries share common repair mechanism, membrane trafficking is monitored as the PM repairs from such injuries. During the course of repair, dispersed PM injury by the PFT Streptolysin O activates endocytosis, while focal mechanical injury to the PM inhibits endocytosis. Consequently, acute block of endocytosis prevents repair of diffuse, but not of focal injury. In contrast, a chronic block in endocytosis depletes cells of early endosomes and inhibits repair of focal injury. This study finds that both focal and diffuse PM injury activate Ca2+‐triggered exocytosis of early endosomes. The use of markers including endocytosed cargo, Rab5, Rab11, and VAMP3, all reveal injury‐triggered exocytosis of early endosomes. Inhibiting Rab5 prevents injury‐triggered early endosome exocytosis and phenocopies the failed PM repair of cells chronically depleted of early endosomes. These results identify early endosomes as a Ca2+‐regulated exocytic compartment, and uncover the requirement of their dual functions – endocytosis and regulated exocytosis, to differentially support PM repair based on the nature of the injury.
TAOK3 Facilitates Esophageal Squamous Cell Carcinoma Progression and Cisplatin Resistance Through Augmenting Autophagy Mediated by IRGM
Authors: Sun Mingchuang , Li Zhaoxing , Wang Xiaoyuan , Zhao Meirong , Chu Yuan , Zhang Zehua , Fang Kang , Zhao Ziying , Feng Anqi , Leng Zhuyun , Shi Jianing , Zhang Li , Chen Tao , Xu Meidong 
Published: September 2023

AbstractEsophageal squamous cell carcinoma (ESCC) is one of the deadliest cancers because of its robust aggressive phenotype and chemoresistance. TAO kinase belongs to mitogen‐activated protein kinases, which mediate drug resistance in multiple cancers. However, the role of TAO kinase in ESCC progression and chemoresistance has never been explored. Here, it is reported that TAOK3 augments cell autophagy and further promotes ESCC progression and chemoresistance. Mechanistically, TAOK3 phosphorylates KMT2C at S4588 and strengthens the interaction between KMT2C and ETV5. Consequently, the nuclear translocation of KMT2C is increased, and the transcription of autophagy‐relevant gene IRGM is further upregulated. Additionally, the inhibitor SBI‐581 can significantly suppress cell autophagy mediated by TAOK3 and synergizes with cisplatin to treat ESCC in vitro and in vivo.
PGAM1 Inhibition Promotes HCC Ferroptosis and Synergizes with Anti‐PD‐1 Immunotherapy
Authors: Zheng Yimin , Wang Yining , Lu Zhou , Wan Jinkai , Jiang Lulu , Song Danjun , Wei Chuanyuan , Gao Chao , Shi Guoming , Zhou Jian , Fan Jia , Ke Aiwu , Zhou Lu , Cai Jiabin 
Published: September 2023

AbstractThe combination of immunotherapy and molecular targeted therapy exhibits promising therapeutic efficacy in hepatocellular carcinoma (HCC), but the underlying mechanism is still unclear. Here, phosphoglycerate mutase 1 (PGAM1) is identified as a novel immunometabolic target by using a bioinformatic algorithm based on multiple HCC datasets. PGAM1 is highly expressed in HCC and associated with a poor prognosis and a poor response to immunotherapy. In vitro and in vivo experiments indicate that targeting PGAM1 inhibited HCC cell growth and promoted the infiltration of CD8+ T‐cells due to decreased enzymatic activity. Mechanistically, inhibition of PGAM1 promotes HCC cell ferroptosis by downregulating Lipocalin (LCN2) by inducing energy stress and ROS‐dependent AKT inhibition, which can also downregulate Programmed death 1‐ligand 1 (PD‐L1). Moreover, an allosteric PGAM1 inhibitor (KH3) exhibits good antitumor effects in patient‐derived xenograft (PDX) models and enhanced the efficacy of anti‐PD‐1 immunotherapy in subcutaneous and orthotopic HCC models. Taken together, the findings demonstrate that PGAM1 inhibition exerts an antitumor effect by promoting ferroptosis and CD8+ T‐cell infiltration and can synergize with anti‐PD‐1 immunotherapy in HCC. Targeting PGAM1 can be a promising new strategy of “killing two birds with one stone” for HCC treatment.
A follow‐up survey to assess stakeholders’ perspectives on weed management challenges and current practices in Nebraska, USA
Authors: McDonald Shawn T. , Sarangi Debalin , Rees Jennifer M. , Jhala Amit J. 
Published: September 2023

AbstractStakeholders across the state of Nebraska, USA, were surveyed in 2019–2020 to assess problem weeds and weed management practices in agronomic crops. A total of 420 complete responses were obtained across four Nebraska districts (Northeast, Panhandle, Southeast, and West Central). Accumulated across the state, 65.5% of farmed or scouted crop ground in Nebraska was under no‐till production, with the major crops being corn and soybean representing 39.3% and 30.7% of agronomic crop production area, respectively. Palmer amaranth, horseweed, waterhemp, kochia, and giant ragweed were ranked the most problematic weeds. In a 2014–2015 survey, Palmer amaranth was the sixth most problematic weed. The most used preplant herbicides were 2,4‐D, glyphosate, and dicamba in the 2019–2020 survey. Atrazine applied alone or in mixture with acetochlor, bicyclopyrone, clopyralid, mesotrione, or S‐metolachlor were the most applied pre‐emergence (PRE) herbicides in corn, whereas the most applied PRE herbicides in soybean were metribuzin/sulfentrazone, flumioxazin/pyroxasulfone, and chloransulam‐methyl/sulfentrazone. Like the previous survey, glyphosate was the most frequent choice of survey respondents as a post‐emergence (POST) herbicide in glyphosate‐resistant corn and soybean, while 2,4‐D was the most applied POST herbicide in grain sorghum and wheat. Most of the respondents (77%) were aware of the new multiple herbicide‐resistant crops, and 86% listed physical drift and volatility of dicamba/2,4‐D as a primary concern. Twenty‐three percent of survey respondents identified integrated pest management as a primary research and extension priority for profitable agronomic crop production in Nebraska.
Targeted dosing of anti‐thymocyte globulin in adult unmanipulated haploidentical peripheral blood stem cell transplantation: A single‐arm, phase 2 trial
Authors: Wang Haitao , Wang Nan , Wang Lili , Du Jishan , Li Fei , Shao Yangliu , Peng Bo , Luan Songhua , Wang Lu , Jin Xiangshu , Gao Chunji , Dou Liping , Liu Daihong 
Published: September 2023

AbstractAnti‐thymocyte globulin (ATG) is widely used in allogeneic hematopoietic stem cell transplantation to prevent severe graft‐versus‐host disease (GVHD) and graft failure. However, overexposure to ATG may increase cytomegalovirus (CMV), Epstein‐Barr virus (EBV) reactivation, non‐relapse mortality, and disease recurrence. To investigate the optimal dosing of ATG, we established a targeted dosing strategy based on ATG concentration monitoring for haploidentical peripheral blood stem cell transplantation (haplo‐PBSCT). The aim of this phase 2 trial is to evaluate the safety and efficacy of the ATG‐targeted dosing strategy in adult unmanipulated haplo‐PBSCT. ATG was administered for 4 days (−5 days to −2 days) during conditioning. The ATG doses on −3 days and −2 days were adjusted by our dosing strategy to achieve the optimal ATG exposure. The primary endpoint was CMV reactivation on +180 days. Between December 2020 and January 2022, 66 haplo‐PBSCT patients were enrolled and 63 of them were evaluable with a median follow‐up of 632 days. The cumulative incidence of CMV reactivation was 36.7% and that of EBV was 58.7%. The 1‐year disease‐free survival was 82.5%, overall survival was 92.1%, and CD4+ T‐cell reconstruction on +100 days was 76.8%. The most common severe regimen‐associated toxicities (> grade 3) were infections (51.5%) and gastrointestinal toxicity (25.5%). A total of 102 haplo‐PBSCT patients who received the conventional fixed ATG dose (cumulative 10 mg/kg) comprised historical control. The outcomes in historical control were inferior to those of phase 2 trial cohort (CMV reactivation: 70.8%, p < .001; EBV reactivation: 76.0%, p = .024; CD4 + T‐cell reconstruction: 54.1%, p = .040). In conclusion, ATG‐targeted dosing strategy reduced CMV/EBV reactivation and improved survival without increasing GVHD after haplo‐PBSCT. These advantages may be associated with accelerated immune reconstitution.
Woodhouse–Sakati syndrome in an Indian patient with a novel pathogenic variant
Authors: Amalnath S. Deepak , Jothivanan  , Oshima Junko , Buchan Jillian G. , Paolucci Sarah 
Published: September 2023

AbstractWoodhouse–Sakati syndrome consists of hypogonadism, diabetes mellitus, alopecia, ECG abnormalities, and dystonia. This condition is caused by the loss of function of the DCAF17 gene. Most of the patients have been reported from Greater Middle Eastern countries. We report a 38 male from southern India who presented with syncope and massive hemoptysis due to ruptured bronchopulmonary collaterals. He also had alopecia, cataracts, recently diagnosed diabetes and hypogonadism. Whole exome sequencing showed a novel homozygous truncating variant in the DCAF17 gene. Despite embolization of the aortopulmonary collaterals, the patient died of recurrent hemoptysis.