bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tectonostratigraphic controls on pore fluid pressure distribution across the Taranaki Basin, New Zealand
Authors: O'Neill Sean R. , Jones Stuart J. , Kamp Peter J. J. 
Published: January 2023

AbstractSignificant variations in pore pressure across the Taranaki Basin, New Zealand, are attributed to changes in lithofacies and structure, usefully illustrated in terms of ten areas that we term geopressure provinces, each displaying individual pore pressure trends. Cretaceous to Early Miocene formations in different parts of the basin can be either normally pressured (near or at hydrostatic) or significantly overpressured (up to 28 MPa) at the same depth. Variations in Eocene–Oligocene facies types and thicknesses both within and between geopressure provinces provide first‐order control on the magnitude, distribution and maintenance of overpressure across the basin. Examples of hydraulic compartmentalisation due to sealing faults and stratigraphic architecture are identified within the basin. Deep pore pressure transitions are sealed by diagenetic, structural or stratigraphic mechanisms in different places and are associated with an increase in mudrock volume (reduced permeability) or gas generation. Thus, pore pressure distribution in the Taranaki Basin is controlled by a combination of sediment loading, lithofacies variations, fault zone permeability and structural architecture. This work represents an appraisal of the pore pressure distribution across the whole of a multiphase structurally complex basin, and the approach taken provides a framework for better understanding the distribution of pore fluid pressures and pore fluid migration in other sedimentary basins.
Differential proteomic expression in indolent versus transforming oral lichen planus
Authors: Xie Fangyi , Gleue Casey A. , Deschaine Maria , Dasari Surendra , Sartori‐Valinotti Julio C. , Charlesworth M. Cristine , Meves Alexander , Lehman Julia S. 
Published: January 2023

AbstractOral lichen planus (OLP) confers an approximately 1% risk of transformation to oral squamous cell carcinoma (OSCC). Early identification of high‐risk OLP would be very helpful for optimal patient management. We aimed to discover specific tissue‐based protein biomarkers in patients with OLP who developed OSCC compared to those who did not. We used laser capture microdissection– and nanoLC–tandem mass spectrometry to assess protein expression in fixed lesional mucosal specimens in patients with indolent OLP (no OSCC after at least 5‐year follow‐up, n = 6), transforming OLP (non‐dysplastic epithelium with lichenoid inflammation marginal to OSCC, n = 6) or normal oral mucosa (NOM, n = 5). Transforming OLP protein profile was enriched for actin cytoskeleton, mitochondrial dysfunction and oxidative phosphorylation pathways. CA1, TNNT3, SYNM and MB were overexpressed, and FBLN1 was underexpressed in transforming OLP compared with indolent OLP. Integrin signalling and antigen presentation pathways were enriched in both indolent and transforming OLP compared with NOM. This proteomic study provides potential biomarkers, such as CA1 overexpression, for higher‐risk OLP. While further validation studies are needed, we propose that epithelial–mesenchymal transition may be involved in OLP carcinogenesis.
Preliminary analysis of mucosal and salivary bacterial communities in oral lichen planus
Authors: Du Guanhuan , Deng Yiwen , Pan Lei , Han Xiaozhe , Tang Guoyao , Yu Shiyan 
Published: January 2023

AbstractObjectiveTo characterize the bacterial community from different oral niches (buccal mucosa and saliva) in oral lichen planus (OLP) patients.Subjects and MethodsThis preliminary study analyzed site‐specific (mucosa and saliva) microbial landscape of 20 OLP patients and 10 healthy controls.ResultsThe microbial diversity was similar between OLP patients and healthy controls in both salivary and mucosal communities. However, the topological properties of co‐occurrence networks of salivary and mucosal microbiome were different between healthy controls and OLP patients. SparCC analysis inferred three and five keystone taxa in the salivary and mucosal microbial networks of healthy controls, respectively. However, in the salivary and mucosal bacterial networks of OLP patients, only one hub OTU and three OTUs were identified as keystone taxa, respectively. In addition, analysis of community cohesion revealed that mucosal microbial community in OLP patients had lower stability than that in healthy controls. In final, correlation assay showed that the clinical severity of OLP was positively associated with the relative abundance of Rothia in saliva but negatively associated with that of Porphyromonas on mucosa.ConclusionsThe salivary and mucosal bacterial communities of OLP patients differ in terms of composition, the genera associated with OLP severity, and co‐occurrence patterns.
Contralateral Prophylactic Mastectomy among Women with Pathogenic Variants in BRCA1/2: Overall Survival, Racial, and Ethnic Differences
Authors: Makhnoon Sukh , Gutierrez Barrera Angelica M. , Bassett Roland , Afrough Aimaz , Bedrosian Isabelle , Arun Banu K. 
Published: January 2023

Background. Patients with unilateral breast cancer carrying pathogenic variants in BRCA1/2 have the option to undergo contralateral prophylactic mastectomy (CPM). However, differences in CPM use and survival outcomes following CPM are poorly understood in this high-risk population, in part due to a lack of data from contemporary clinical cohorts. The objective of this study was to evaluate post-CPM overall survival (OS) and related racial/ethnic differences in a contemporary clinical cohort. Methods. We retrospectively reviewed the medical records of women with a personal history of unilateral breast cancer carrying pathogenic variants in BRCA1/2 who were diagnosed between 1996 and 2012. Genetic test results, self-reported demographic characteristics, and clinical factors were abstracted from electronic medical records. Results. Of 144 BRCA-positive patients, the majority were White (79.2%, n = 114). Overall, 56.1% (n = 81) of all BRCA1/2 carriers chose to undergo CPM, with no racial/ethnic difference in CPM election (

p

= 0.78). Of 81 patients who underwent CPM, there is strong evidence of a difference in survival between the racial/ethnic groups, with White patients having the highest OS compared to non-White patients (

p

= 0.001). Of the 63 patients who did not undergo CPM, there is no racial/ethnic difference in overall survival (

p

= 0.61). In multivariable cox regression, adjusted for demographic and clinical characteristics, OS was significantly lower among non-Whites than in Whites (HR = 0.39,

p

= 0.04). Conclusions. Evaluation of a contemporary clinical cohort of BRCA-positive women with unilateral breast cancer showed no racial/ethnic difference in CPM use, but there was a significant difference in post-CPM overall survival.
The Comparison of Clinical Epidemiology of Hospitalized Patients with COVID-19 during the Third and Fourth Waves of the Pandemic in Gorgan
Authors: Eshghinia Samira , Sharifi Far Rahmat Allah , Hajimoradloo Naghimeh , Sinesepehr Ali , Sohrsbi Ahmad , Imeri Mousa , Khodanazar Kalti Amir Reza , Rezaie Shirazi Erfan , Golsha Roghieh 
Published: January 2023

Background. COVID-19 has turned into a global public health crisis. This study intended to compare demographic characteristics, disease severity, treatment methods, and clinical outcomes in hospitalized patients with COVID-19 during the third and fourth waves of the pandemic in Golestan Province, Iran. Methods. In this cross-sectional study, the clinical epidemiology of all COVID-19 patients, who were hospitalized in two educational hospitals in Golestan Province for 30 days from the start of the third and fourth waves of the coronavirus pandemic in 2021-2022, was assessed. Their electronic medical records were used to collect their epidemiological, demographic, laboratory, and clinical information and treatment outcome. Results. In all, 930 electronic medical records of the hospitalized patients (351 in the third wave and 579 in the fourth wave) were studied. In the third and fourth waves, 29.06% and 13.13% of the patients had severe COVID-19, respectively (

P

= 0.001). The number of deaths in the third wave was larger compared to the fourth wave (

P

= 0.015). The mean duration of hospitalization was longer in the third wave than in the fourth wave (

P

= 0.001). The drugs administered most in these two waves were remdesivir, dexamethasone, and heparin, and the patients who received these drugs were compared in the third and fourth waves (

P

= 0.001). Conclusion. The reduced rate of mortality in the fourth wave was compared to the third wave. This reduction can be attributed to the change in the national strategy adopted in terms of hospitalization criteria and treatment protocols taking into account the acquired experience, earlier hospitalization, and start of drug therapy.
Comparison of continuous headache features in youth with migraine, new daily persistent headache, and persistent post-traumatic headache
Authors: Patterson Gentile Carlyn , Aguirre Geoffrey K , Hershey Andrew D , Szperka Christina L 
Published: January 2023

Objective To compare clinical features in youth with continuous headache from migraine, persistent post-traumatic headache, and new daily persistent headache to determine if they are similar, contrary to their distinction in the International Classification of Headache Disorders. Methods We pursued a single center age- and sex-matched observational study comparing the clinical characteristics of 150 youth (11 – 17 years old) with continuous headache from migraine, persistent post-traumatic headache, and new daily persistent headache. A diagnostic algorithm based on international classification of headache disorders criteria was used to identify those with migraine (headache features of migraine with gradual onset), and persistent post-traumatic headache and new daily persistent headache (based on the circumstances of headache onset regardless of headache features). Fifty participants each with migraine, persistent post-traumatic headache, and new daily persistent headache were matched by age and sex. Participant survey responses on headache characteristics were compared. Results Median usual headache severity was 6.0 [95%CI 6.0, 6.0] and was not different across diagnostic groups (H statistic = 1.2, p = 0.55). Headache exacerbation frequency, disability, associated symptoms, and most triggers were not significantly different across groups. The majority of persistent post-traumatic headache and new daily persistent headache had headache features consistent with a diagnose of migraine (72% and 62%, respectively). Conclusion Our findings suggest that most persistent post-traumatic headache and new daily persistent headache may represent abrupt onset of migraine.
MULHERES EXECUTIVAS EVITAM PROBLEMAS FINANCEIROS?
Authors: Silva Fabiano Ferreira da , De Moura André Aroldo Freitas 
Published: January 2023

Objetivo: Esse estudo tem como objetivo investigar se as mulheres no cargo de gestão diminuem a probabilidade de problemas financeiros.
Método: A amostra da empresa compreende empresas Brasileiras listadas na B3, no período de 2010 a 2018. Utilizou-se o modelo de previsão de problemas financeiros de Altman (1979), e dessa forma regrediu-se as variáveis de interesse relacionados a diversidade de gênero em posições de alta gestão via o modelo econométrico logit. Para garantir resultados robustos, usou-se uma técnica recente para balancear empresas que tinham mulheres na alta gestão com seus pares via PSM e entropia.
Resultados: Os resultados sugerem que quando a mulher está como CEO, as empresas têm maior probabilidade de terem problemas financeiros. No entanto, encontramos que essas empresas já estavam com problemas financeiros antes da entrada da mulher como CEO. Em análise adicional, evidenciamos que a mulher evita problemas financeiros apenas quando a mulher assume a presidência do conselho de empresa dois anos antes da empresa apresentar problemas financeiros.
Contribuições: Entender melhor como a diversidade de gênero pode contribuir para a administração de empresas brasileiras, em sua maioria familiares ou com alta concentração acionário, em situações de crise e dificuldades financeiras, haja vista as recorrentes crises políticas que impactaram a economia Brasileira nesta última década.
Land subsidence assessment on karst based on resistivity and geotechnical parameters
Authors: Massinai Muhammad Altin , Massinai Muhammad Fawzy Ismullah , Syamsuddin Erfan 
Published: January 2023

Karst is geomorphologically composed of limestone. However, limestone is very susceptible to weathering due to the influence of water, which can cause land subsidence. The resistivity method is often used to determine the potential for land subsidence, while geotechnical methods are commonly considered capable of juxtaposing with resistivity methods to support interpretation accuracy. The current research was conducted to determine the potential for land subsidence in the karst area in Lappae, South Sulawesi, Indonesia. The resistivity method utilizes a dipole-dipole configuration, and the geotechnical parameters used are uniformity coefficient, curvature coefficient, water content, shear angle, and cohesion. The results obtained can be classified into northern and southern areas. The classification of these areas is based on the resistivity results, which show very high resistivity values (&gt; 4800 Ωm) in the southern part. This value is assumed to be a feature of the cave. Caves are predominantly distributed in the southern part. The five geotechnical parameters show that the northern part, which was composed of massive limestone (150-1600 Ωm), is a stable area, though it is highly prone to landslides. As for the southern part, geotechnical parameters suggest that the presence of caves is the primary factor contributing to the very high potential for landslides in this region. These results indicate that, based on the evaluation of this location, it is not feasible for land use. In addition, in spite of the low cost and rapid methods, the combination of these methods shows good results.
Reducing Pb accumulation in roots of sweet potato under low lead-contaminated soil by Azotobacter inoculation
Authors: Hindersah Reginawanti , Subarja Vera Oktavia , Suryatmana Pujawati , Sudirja Rija , Karuniawan Agung , Hidayat Yusup 
Published: January 2023

Agricultural soil is possibly threatened by lead (Pb) contamination due to the intensive use of fertilizers. The rhizobacteria were recommended for the bioremediation of soils contaminated by low concentrations of Pb. The experiment was conducted to observe the Azotobacter's ability to proliferate in Pb-contaminated broth and to decrease the Pb availability in soil, Pb uptake by sweet potato roots, and sweet potato growth. The resistance test was performed by growing five Azotobacter isolates in N-free broth with various Pb levels. A pot experiment was conducted in a factorial randomized block design to test three levels of Pb in soil and two Azotobacter isolates. The results showed that Azotobacter Azv4 and <em>A. choroococcum</em> were resistant to 100 mg L<sup>-1</sup> Pb in N-free broth. In the pot experiment, Azotobacter Azv4 Inoculation caused less Pb in soil and roots of sweet potatoes grown in Pb-contaminated soil than <em>A. choroococcum</em>. Either Azotobacter or Pb soil did not influence vine length. However, Azv4 was more prominent in increasing branch number, root volume and length; higher Pb in soil reduced branch number but did not affect root parameters. Azotobacter Azv4 increased more shoot and root dry weight compared to <em>A. choroococcum,</em> but both isolates did not change the shoot-to-root ratio (S/R). The Pb contamination only reduced root dry weight and reduced the S/R. This research considered utilizing rhizobacteria Azotobacter for reducing Pb levels in soil and roots; and increasing sweet potato biomass.
Documentary Heritage of 1773–1923 of Siberian Archives with Significance to Lithuania
Authors: Bilotas Viktor 
Published: January 2023

Extensive archival documentation related to Lithuania and Lithuanians is kept in Russia, and not only in St. Petersburg or Moscow. Archival cases of Lithuanians containing high numbers of ego-documents, are dispersed throughout the vast territory, and are especially numerous in the Siberian memory institutions. Thanks to the project Lithuanian Sibiriada, copies of documents brought from Tobolsk, Tomsk, Krasnoyarsk and Irkutsk can be found in the Lithuanian State Historical Archives. By using the analysis of documents and the method of classification, this article tries to systematize the information about the relevant materials found in the state archives of Siberia and to determine their typology.
The studied documentation covering the period between 1773 and 1923 was found to belong to such areas of public life as politics, economics, science, education, culture, religion, administration, law, statistics, labor, and migration. These are documents (ranging from drafts and copies to official originals) produced by Lithuanians themselves, scribes, state officials not only in Siberia, but also in Lithuania, St. Petersburg or other parts of the Russian Empire. By type, among the discovered documents, there are decrees and manifests, deportation sentences, appointment letters, certificates, sheets, decisions, court records, lists, metrics, reports, reviews, statistics, financial documents. In terms of ego-documents, letters, requests, complaints, explanations, and wills can be found. With such texts, people sought to report, ask, defend themselves or those close to them, or bequeath property. The government created documents with the purpose of informing, registering, taxing, deporting, liberating, accommodating, employing, accumulating data; (not) issuing permits, allowances, salaries. Photos were taken for the mass media, identification, or inspection.
Siberian documents touch on such topics as the uprisings, the annexation of the Grand Duchy of Lithuania, attempts of Russification, exiles and prisoners, police surveillance, deaths, liberation, return to the social group, employment, marriage, obtaining a passport, business, resettlement, return to Lithuania. Documentary testimonies are available about free Lithuanians in Siberia: workers and farmers, students and teachers, businesspeople and craftsmen, doctors and priests, officials and various specialists, war refugees and repatriates. The addressees of the letters were the governors’ offices, directorates, courts, various institutions, officials, private people.
The study showed that, between 1773 and 1923, Siberian documents about Lithuanians most frequently concern the deported persons (political, criminal), their data and applications. Yet, there are also archival cases significant for the history of Lithuania about the Lithuanian colonies, various specialists, famous personalities, businesspeople, about events in Lithuania itself.
Análisis radiográfico de los parámetros espinopélvicos obtenidos con el dispositivo de TLIF anterior. Estudio multicéntrico
Authors: Gobbi Enrique Augusto , De Zavalía Máximo , Lanari Zubiaur Felipe , Berjano Ricardo , Ortiz Facundo , Zuliani Pablo , Pons Belmonte Rodrigo 
Published: January 2023

Objetivo: Comunicar los resultados obtenidos según la posición del dispositivo de TLIF anterior.
Materiales y Métodos: Estudio multicéntrico, observacional, analítico, transversal, de recuperación retrospectiva. Se evaluaron los parámetros espinopélvicos prey posoperatorios de espinogramas de 20 pacientes que fueron operados entre septiembre de 2019 y agosto de 2021. Se incluyó a pacientes sometidos a artrodesis lumbar con implante de tipo TLIF anterior. Se excluyó a pacientes sin espinograma pre- oposquirúrgico y más de un dispositivo.
Resultados: La media de la lordosis monosegmentaria fue de 13,33° antes de la cirugía y de 18,81° después (p <0,001). La media de la lordosis monosegmentaria fue de 7,32°; 2,95° y 6,24° para las posiciones I, II y III, respectivamente. La media de la altura discal fue de 6,22 mm en el preoperatorio y 11,06 mm en el posoperatorio (p >0,001).
Conclusiones: Los resultados de la colocación de este tipo de dispositivos y su relación con la lordosis segmentaria fueron alentadores, se comprendió la importancia de la disposición de estos en el extremo anterior del espacio discal.
Nivel de Evidencia: IV
Relationship between strain elastography and histopathological parameters in breast cancer
Authors: ÇORAPLI Mahmut , BULUT Hacı Taner , ÖRMECİ Ayşe Gül , ALAKUŞ Hüseyin 
Published: January 2023

Purpose: This study aimed to evaluate the relationship between strain elastography and immunohistochemical markers, the histologic grade, and molecular subtyping in invasive breast cancer.
Materials and Methods: The relationships between the elastography index values and progesterone receptor, estrogen receptor, human epidermal growth factor receptor 2, Ki-67, the histologic grade, and molecular subtype in 171 patients who had not received neoadjuvant treatment and underwent breast-conserving surgery were evaluated. Strain elastosonography were used to evaluate elastography index.
Results: The mean patient age was 46.871 ± 11.949 years. There were 135, 129, and 90 estrogen receptor-positive, progesterone receptor-positive, and human epidermal growth factor receptor 2-positive patients, respectively. Forty-seven patients had the worst histological grade. Based on molecular subtyping, human epidermal growth factor receptor 2-positive, luminal A, luminal B, and triple-negative classifications were made for 25 (14.5%), 29 (17.0%), 109 (63.7%), and 8 (4.7%) cases, respectively. There was no statistically significant correlation between the elastography index values and estrogen receptor, progesterone receptor, human epidermal growth factor receptor 2, Ki-67, histologic grade, or molecular subtype among these breast resection cases.
Conclusion: The elastography index value was insufficient to predict the specified histopathological parameters.
DYNAMIC PROPERTIES OF CLAY FOR EARTHQUAKE RESPONSE ANALYSIS IN THE BAY OF CAMPECHE
Authors: Taboada Urtuzuástegui Víctor Manuel , Cindy Cao Shuang , Cruz Roque Diego , Flores-López Francisco Alonso , Barrera Prócoro , Gan Kuat C. , Dantal Vishal , Espinosa Samudio Esteban Ernesto , Renovato Carrión Sergio Dionicio , Hernández Durón Juan Manuel 
Published: January 2023

The Bay of Campeche is located in a region of moderate to high seismic activity related to the active triple junction between the North American, Caribbean, and Cocos plate boundaries. Therefore, the fixed offshore platforms and subsea structures in the Bay of Campeche must be designed against earthquake loading. A database was developed of classification and index properties tests, in situ measurements of shear wave velocity using downhole P-S suspension seismic velocity logging, in situ piezocone penetration tests, resonant column tests to characterize the shear modulus and material damping ratio at small shear strains (10−5 % to about 0.1 %), and strain-controlled cyclic direct simple shear tests to evaluate the decrease of shear modulus and the increase of material damping ratio at large shear strains (0.1 % to about 10 %) performed on clays from the Bay of Campeche, including clays with no carbonate content to 100 % carbonate content, retrieved from the seafloor to a penetration depth of 120 m below seafloor. The database was tailored specifically to develop empirical correlations for the Bay of Campeche clay to determine Vs when in situ measurements of Vs are not available and to develop numerical modeling to predict the variation of the normalized shear modulus (G/Gmax) and material damping ratio as a function of shear strains (g) when dynamic test results are unavailable for all the clay layers. The equations developed to calculate Vs and the curves of G/Gmax-g and D-g of Bay of Campeche clays are recommended for preliminary or perhaps even final seismic site response evaluations.