bluuebunny/crossref_metadata_2025_split huggingface dataset:
Numerical simulations of plasmonic properties of spherical gold nanodisks using T-matrix method: impact of geometry parameters on the sensitivity to the dielectric environment and the field enhancement
Authors: AL-Qadi Bassam 
Published: December 2022

Abstract
Simulations using the transition matrix approach are implemented for spherical gold nanodisks (AuNDs) to obtain insights into their plasmonic properties. We systematically follow the correlation between the optical response of these nanostructures with their geometry parameters and the refractive index of the surrounding medium. Plasmon wavelengths linearly redshift with the diameter-to-height aspect ratio, which is consistent with measured data available in the literature, thereby ensuring calculation accuracy. The relative plasmon resonance shift to the relative increment of the medium refractive index is geometry-dependent and exhibits a linear correlation in which the estimated slope represents the plasmon resonance sensitivity. We confirm the strong dependence of the field enhancement factor on the geometry parameters of nanodisks. The relative contributions of scattering and absorption in the extinction spectra are determined. Simulations show that circular AuNDs have well-controlled optical characteristics that will provide great opportunities to achieve various plasmon-derived applications.
Synthesis of MnSi1.7 nanosheet bundles from CaSi2 crystal powders using MnCl2 in molten salt
Authors: Komeda Fumio , Itoh Shogo , Shimura Yosuke , Takahashi Naohisa , Tatsuoka Hirokazu 
Published: December 2022

Abstract
MnSi1.7 nanosheet bundles with an improved homogeneous composition were synthesized by annealing from CaSi2 crystal powders with MnCl2 in molten salt. The MnSi and Si phases were formed at the initial stage of the synthesis with an inhomogeneous Mn distribution within the nanosheet bundles. Subsequently, the phases were transformed into MnSi1.7 with an improved homogeneous Mn distribution within them for 10 h annealing in the molten salt. The formation of multiple Mn-silicide phases and remarkable improvement in the structural homogeneity of the MnSi1.7 nanosheet bundles were discussed in terms of the reactions of Mn or Si with chloride compounds, decomposition of chlorides at elevated temperatures, phase selection of multiple silicide phases, shrinkage of the volume from Si to MnSi1.7, and dominant diffusion species. Multiple growth variants of the MnSi1.7 domains were stacked in the nanosheets. For comparison, the growth in a deliquescent environment realized by NH4Cl addition was examined.
Images in Immunotherapy and Precision Oncology: Angiosarcoma of the Spleen and Liver
Authors: Deshpande Anagha , Munoz Javier , Kelemen Katalin , Dabak Vrushali , Hanbali Amr , Kurzrock Razelle 
Published: December 2022

ABSTRACT
Primary splenic or hepatic angiosarcomas are ultra-rare and aggressive malignancies associated with poor prognosis. The mainstay treatments are surgical resection and chemotherapy. We report a case of angiosarcoma in a 50-year-old woman who presented with bruising, fatigue, ecchymosis, and hepatosplenomegaly. She was treated with the multi-kinase inhibitor sunitinib for 4 weeks before developing a splenic hemorrhage and succumbing. Recent studies have demonstrated the clinical benefit of immunotherapies in angiosarcomas. Additionally, sequencing techniques have showcased the diverse molecular aberrations involved in angiosarcomas, which offer opportunities for precision-matched targeted therapies such as inhibitors of the VEGF/VEGFR axis and PI3K/Akt/mTor pathway.
MOTIVASI BELAJAR DAN RESILIENSI AKADEMIK SELAMA PEMBELAJARAN JARAK JAUH DI MASA PANDEMI COVID-19
Authors: Syifa Akmaliyah  , Nuram Mubina  , Nita Rohayati  
Published: December 2022

Kondisi pandemi covid-19 mengakibatkan perubahan yang luar biasa dalam bidang pendidikan, termasuk dalam hal pembelajaran, yaitu metode pembelajaran yang secara mendadak harus dilakukan secara jarak jauh atau melalui media pembelajaran daring. Tujuan dalam penelitian ini adalah untuk mengetahui adakah pengaruh motivasi belajar terhadap resiliensi akademik pada siswa kelas VIII di SMP Negeri 1 Pebayuran selama pembelajaran jarak jauh di masa pandemi covid-19. Subjek dalam penelitian ini berjumlah 195 orang siswa kelas VIII di SMP Negeri 1 Pebayuran. Penelitian ini menggunakan metode penelitian kuantitatif asosiatif. Teknik yang digunakan dalam penelitian ini adalah quota sampling dengan ciri-ciri tertentu sampai jumlah yang sudah ditentukan. Pengambilan data menggunakan dua skala likert yaitu skala resiliensi akademik dan skala motivasi belajar. Analisis data penelitian ini menggunakan analisis regresi linier sederhana. Berdasarkan hasil uji regresi linier sederhana didapatkan nilai sig. sebesar 0,001 < 0,05 (H0 ditolak dan Ha diterima) dan persamaan regresi yaitu Y = 43,789 + 0,296, maka terdapat pengaruh positif motivasi belajar terhadap resiliensi akademik.
The condition of the covid-19 pandemic made extraordinary changes in the field of education, including in terms of learning, namely learning methods that suddenly have to be carried out remotely or through online learning media. Therefore, the students must have high resilience. Thus, students can adapt to change in the learning process. The purpose of this study was to determine whether there is an influence learning motivation on academic resilience in class VIII students at SMP Negeri 1 Pebayuran during online learning in the covid-19 pandemic. The subjects in this study amounted to 195 in class VIII students at SMP Negeri 1 Pebayuran. This study uses associative quantitative researchmethods. The technique used in this research is quota sampling with certain characteristics up to a predetermined amount. Data collection used two Likert scales, namely the academic resilience scale and the learning motivation scale. The data analysis of this research used simple regression analysis. Based on the results of a simple linear regression test obtained the value of sig. of 0.001 < 0.05 (H0 is rejected and Ha is accapted) and the regression equation is Y = 43.789 + 0.296. Then there is a positive influence learning motivation on academic resilience.
PENGARUH CITRA MEREK TERHADAP KEPUTUSAN PEMBELIAN BIMBINGAN BELAJAR ONLINE RUANG GURU DI SMAN 1 BANYUSARI KARAWANG
Authors: Siti Sulikah  , Lania Muharsih  , Marhisar Simatupang  
Published: December 2022

Revolusi industri 4.0 berdampak pada dunia pendidikan di Indonesia, sehingga pembelajaran dapat dilakukan dengan berbagai media teknologi. Saat ini seluruh dunia termasuk Indonesia sedang menghadapi pandemi Covid-19 sehingga pembelajaran harus dilakukan dalam jaringan (daring). Fakta menunjukkan bahwa di masa pandemi kenaikan keputusan pembelian pengguna bimbingan belajar online Ruangguru meningkat tinggi, salah satu faktor yang memengaruhi keputusan pembelian adalah citra merek. Keputusan pembelian dalam penelitian ini sebagai variabel dependen dan citra merek sebagai variabel independen. Populasi dalam penelitian ini adalah pengguna Ruangguru SMAN 1 Banyusari Karawang sebanyak 317 siswa yang diambil sampelnya sebanyak 176 siswa. Hasil penelitian yang dilakukan menunjukkan bahwa citra merek berpengaruh terhadap keputusan pembelian dengan nilai thitung 9,494>1,973 ttabel dengan nilai signifikansi 0,000<0,05 yang artinya Ha diterima dan H0 ditolak. Nilai R square diperoleh sebesar 0,341 yang artinya pengaruh citra merek terhadap keputusan pembelian sebesar 34,1% sedangkan sisanya 65,9% dipengaruhi oleh variabel-variabel lain yang tidak termasuk dalam penelitian ini.
The industrial revolution 4.0 has an impact on the world of education in Indonesia, so learning can be done with various technological media. Currently, the whole world, including Indonesia, is facing the Covid-19 pandemic, so learning must be done online. The fact shows that during the pandemic, the purchase decision of Ruangguru online tutoring users has increased significantly, one of the factors that influence purchasing decisions is brand image. Purchase decisions in this study as the dependent variable and brand image as the independent variable. The population in this study were the users of Ruangguru SMAN 1 Banyusari Karawang as many as 317 students and 176 students were taken as samples. The results of the research conducted indicate that brand image has an effect on purchasing decisions with a tcount of 9.494>1.973 t table with a significance value of 0.000<0.05, which means Ha is accepted and H0 is rejected. The value of R square obtained is 0.341, which means that the influence of brand image on purchasing decisions is 34.1% while the remaining 65.9% is influenced by other variables not included in this study.
THE INFLUENCE OF MOTIVATION, SUPERVISION AND LEADER-MEMBER EXCHANGE (LMX) ON EMPLOYEE PERFORMANCE WITH TURNOVER INTENTION AS AN INTERVENING VARIABLE AT PT BANK MESTIKA DHARMA, TBK PEMATANG SIANTAR CITY
Authors: Nitalia Nitalia , Butarbutar Marisi , Efendi Efendi 
Published: December 2022

Hasil peneltiian dapat disimpulkan sebagai berikut: 1. Motivasi sudah baik, pengawasan sudah baik, leader member exchange sudah baik, turnover intention sudah rendah dan kinerja karyawan sudah baik. 2. Motivasi, pengawasan, leader member exchange berpengaruh negatif dan signfikan terhadap turnover intention baik secara simultan maupun parsial kemudian turnover intention berpengaruh negatif dan signifikan terhadap kinerja karyawan. 3. Terdapat hubungan antara variabel bebas dimana terdapat hubungan yang rendah antara motivasi dengan pengawasan kemudian terdapat hubungan yang sedang antara pengawasan dengan leader member exchange dan terdapat hubungan yang sedang antara motivasi dengan leader member exchange. Terdapat hubungan antara variabel bebas dan terikat, terdapat hubungan yang kuat antara motivasi dengan turnover intention. Hubungan yang kuat antara pengawasan dengan turnover intention. Hubungan yang kuat antara leader member exchange dengan turnover. Hubungan yang sangat kuat antara motivasi, pengawasan, leader member exchange dengan turnover intention. Hubungan yang sangat kuat antara turnover intention dengan kinerja karyawan. 4. Hasil uji hipotesis H0 ditolak, artinya motivasi, pengawasan dan leader member exchange berpengaruh negatif signfikan terhadap turnover intention baik secara simultan maupun parsial. The research results can be summarized as follows: 1. Motivation is good, Supervision is good, leader-member exchange is good, the turnover intention is low and employee performance is good. 2. Motivation, Supervision, leader member exchange have a negative and significant effect on turnover intention both simultaneously and partially then turnover intention has a negative and significant effect on employee performance. 3. There is a relationship between the independent variables with a low relationship between motivation and Supervision, a moderate relationship between Supervision and leader-member exchange, and a moderate relationship between motivation and leader member exchange. There is a relationship between the independent and dependent variables, there is a strong relationship between motivation and turnover intention. There is a strong relationship between supervision and turnover intention. There is a strong relationship between leader member exchange and turnover. There is a strong relationship between motivation, Supervision, leader member exchange and turnover intention. There is a very strong relationship between turnover intention and employee performance. 4. The results of the H0 hypothesis test are rejected, meaning that motivation, Supervision and leader member exchange significantly negatively affect turnover intention simultaneously and partially.
Melanoma, molecular and genetic aspects of etiopathogenesis: classification, epidemiology, risk factors, braf and nras mutations
Authors: Казубская Татьяна , Мехеда Лариса , Трофимов Евгений , Фомина Лилия Яшаровна , Харкевич Галина , Белышева Татьяна , Козлова Валентина , Сорокина София , Фридман Марина 
Published: December 2022

Меланома относится к злокачественным опухолям со склонностью к раннему метастазированию и высокой смертностью, несмотря на современные возможности лечения. Развитие молекулярно-генетических технологий позволило выявить сложный мутационный состав, показавший внутриопухолевую микрогетерогенность меланомы, приводящий к трудности её лечения. Идентифицировано множество связанных с меланомой соматических и герминальных мутаций в генах, ряд которых, так называемые «драйверные гены», вероятнее всего включаются в опухолевую прогрессию и являются основными в молекулярной классификации меланомы. В обзоре представлены эпидемиологические, клинические и патологические характеристики меланомы, проведен анализ факторов риска и генетических изменений в генах BRAF, NRAS, KIT, NF1, RAC1 для разных форм меланомы в зависимости от источника первичной опухоли (кожа, слизистые оболочки, оболочки глаза). Обсуждаются разнообразные онкогенные изменения в невусах и подтипах меланомы, связанных и не связанных с солнечной экспозицией. Приводятся данные о герминальных и соматических мутациях в генах CDKN2A, BAP1, TERT, MITF и др., обнаруженных в меланоме, анализ которых позволяет дополнить знания о причинных механизмах возникновения заболевания.
Oncological safety of oncoplastic surgery in breast cancer patients
Authors: Омарова Джанет , Зикиряходжаев Азизжон , Усов Федор , Хугаева Фатима , Дуадзе Илона , Босиева Алана , Куприянов Петр , Решетов Игорь , Каприн Андрей 
Published: December 2022

Цель. Оценить онкологическую безопасность выполнения онкопластических резекций (ОПР) молочных желез у больных раком молочной железы.
Материалы и методы. Проведено ретропроспективное когортное контролируемое клиническое исследование с включением 400 больных раком молочной железы 0-IIIC стадий, которым с 2013 по 2020 годы выполнено органосохраняющие операции: онкопластические (n=200) и классические радикальные резекции (n=200).
Результаты. Группы проанализированы в соответствии с клиническими и патоморфологическими параметрами: достоверно значимые различия обнаружены при анализе менструального статуса, возраста, размера опухоли, ширины ближнего края резекции (p<0,05). Медиана наблюдения составила 49 месяцев. Частота рецидивирования после ОПР и классических органосохраняющих операций (ОСО) составила 8% и 2% соответственно (p=0,006). Шансы рецидива в группе классических ОСО были ниже в 4,261 раза по сравнению с группой ОПР (ОШ=0,235; 95% ДИ: 0,077-0,715). Статистически значимых различий в частоте прогрессирования и летальных исходов между двумя исследуемыми группами не выявлено. Показатели пятилетней выживаемости без локорегионального рецидива составили 91% и 97% в группах ОПР и классических ОСО соответственно. Достоверно значимых различий в общей и безрецидивной выживаемости в группах не выявлено. Проанализировано влияние клинико-патоморфологических показателей на частоту рецидивирования. Факторами неблагоприятного прогноза явились отсутствие экспрессии рецепторов эстрогена и прогестерона (p<0,001), гормональной (p<0,001) и лучевой терапии (p=0,012), наличие низкодифференцированнанного рака (рG3=0,024), тройной негативный и нелюминальный Her2/neu-позитивный тип опухоли (p<0,001). Частота рецидивирования была выше при сохраненном менструальном статусе пациенток (р=0,004). Пациентки с диагностированным местным рецидивом были значимо моложе (р=0,001).
Выводы. Различий между показателями общей и безрецидивной выживаемости после ОПР и классических ОСО не выявлено. При планировании органосохраняющего хирургического лечения необходим индивидуализированный подход с учетом неблагоприятных прогностических факторов. Для изучения вопроса частоты рецидивирвания после онкопластических резекций требуется выполнение крупных клинических исследований.
Ключевые слова: рак молочной железы, органосохраняющие операции, онкопластические резекции, радикальные резекции, рецидивы, безрецидивная выживаемость, факторы прогноза.
Artificial intelligence in the diagnosis of benign skin tumors in pediatric patients. Neural network integration into a mobile app
Authors: Хабарова Рина , Кулева Светлана 
Published: December 2022

Введение. Десятилетие назад искусственный интеллект (ИИ), в частности нейронные сети (НС), как диагностическая опция в практике врача казался лишь отдаленной перспективой. На сегодняшний день применение ИИ во всех сферах клинической и фундаментальной медицины является все более востребованным и ежедневно совершенствующимся подходом.
Цель исследования. Разработка НС и ее обучение распознаванию четырех типов доброкачественных меланоцитарных новообразований кожи, интеграция искусственного интеллекта в мобильное приложение.
Материал и методы. 600 пациентам детского возраста были проведены клиническое и дерматоскопическое исследования новообразований кожи. У части пациентов (n=65) элементы были удалены и патоморфологически верифицированы. В 43% (n=28) был выявлен дермальный невус, в 33,8% (n=22) ― сложный невус, в 10,8% (n=7) ― пиогенная гранулема, в 6,2% (n=4) ― невус Шпиц, по 3,1% (n=2) были вариантами голубой невус и меланома кожи. Семь пациентов с пиогенными гранулемами и 2 с меланомой были исключены из тестовой выборки во время обучения НС. В обучающей выборке была проведена аугментация, тем самым, база была увеличена с 600 до 1800 изображений. НС написана на языке программирования Python с использованием фрэймворка для машинного обучения TensorFlow 2.0. Архитектура сети основана на предварительно обученной модели «EfficientNet B7» с применением парадигмы «обучения с учителем».
Результаты. После периода обучения на тестовой когорте достигнута 83 % точность распознавания четырех типов меланоцитарных невусов. Несмотря на ограниченную выборку, чувствительность метода в зависимости от класса новообразования составила 100% (голубой невус), 73% (сложный невус), 93% (дермальный невус) и 75% (невус Шпиц), специфичность ― 98, 94, 82 и 98% соответственно. Помимо разработки и обучения искусственный интеллект интегрирован в мобильное приложение «KIDS NEVI», что обеспечило практическое применение метода.
Заключение. ИИ в качестве вспомогательного метода диагностики меланоцитарных новообразований кожи у детей и подростков продемонстрировал высокий потенциал. Несмотря на ограниченную выборку, в настоящем исследовании представлены большие достижения в информативности данной диагностической методики.
ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI PENDAPATAN UMKM PADA MASA PANDEMI COVID-19 TAHUN 2021
Authors: Rapii Muhammad , Riswanto Agus , Febriani Lia 
Published: December 2022

At the global economic level, the Covid-19 pandemic has provided a very significant impact on the country's domestic economy and the existence of Small and Medium Micro Business (SMEs). The Organisation for Economic Co-operation and Development (OECD) stated that the pandemic has implications for the threat of a major crisis marked by the cessation of production activities in many countries, the reduction of public consumption, loss of cosumer confidence, and stock crash which ultimately leads to uncertainty. This study aims to determine: (1) the effect of social distancing of income, (2) the effect of raw material prices of income, (3) the effect of technology of income, (4) the effect of consumption of income. This study was a causal research. The subjects were SMEs in the village of Sikur Induk as many as 50 SMEs. The sampling method was used Non Probability sampling technique. The technique of collecting data was used questionaires. Validity and reliability tests conducted on 50 people. Data analysis technique was used multiple linear regression. The results of this study indicated that(1) there is a negative the effect of social distancing of income. Proved by a regression the value of t is greather than t table (-2,198 -2,014), (2) There is a positive effect of raw material prices of income. Proved by a regression the value of t is greather than t table (2,136 2,014), (3) there is a positive effect of technology of income. Proved by a regression the value of t is greather than t table (3,708 2,014), (4) there is a negative effect of consumption of income. Proved by a regression the value of t is greather than t table (-2,863 -2,014), (5) there is a positive influence of social distancing, raw material prices, technology, and consumption of income. Proved by a regression the value of F is greather than F table (9,367 2,58).
Üçüncü Yaş Turizmine Yönelik Algı Ölçeği Geliştirme Çalışması
Authors: KARACA Şükran , ÖZKAN ÖNEM Esra , YILDIZ Muhammed 
Published: December 2022

Amaç: Çalışmanın temel amacı, üçüncü yaş turizmine yönelik beşli likert tipi bir algı ölçeği geliştirmektir.
Yöntem: Geliştirilmesi planlanan ölçek için ilk olarak alanyazın taraması yapılmış ve daha sonra uzman görüşüne başvurularak 30 maddelik bir ölçek formu oluşturulmuştur. Türkiye’de yaşayan 65 yaş ve üzeri 314 kişiden çevrimiçi anket tekniği ile veriler elde edilmiştir. Katılımcılardan elde edilen veriler SPSS ve AMOS programları aracılığıyla analize tabi tutulmuştur. Açımlayıcı ve doğrulayıcı faktör analizleri, güvenilirlik ve geçerlilik analizleri yapılmıştır.
Bulgular: Açımlayıcı faktör analizi sonucunda faktör yükleri 0.45’in altında kalan ve çift yükleme yapılan ifadeler çıkarılmış ve 21 ifadeden oluşan dört boyutlu bir ölçek elde edilmiştir. Boyutlar; tercih, teşvik, tesis imkanları ve nitelik olarak adlandırılmıştır. Ölçeğin KMO değeri 0.870 olarak hesaplanmış ve ortaya çıkan boyutların toplam varyansın %56.387’sini açıkladığı görülmüştür. Ardından doğrulayıcı faktör analizi yapılarak uyum indeksi değerlerine bakılmış ve değerlerin iyi uyum sağladıkları belirlenmiştir. Daha sonra geçerliliği test edilen ölçeğin güvenirlik analizi yapılmış ve Cronbach Alfa değeri 0.866 olarak bulunmuştur.
Tartışma: Geliştirilen üçüncü yaş turizmine yönelik algı ölçeğinin geçerli ve güvenilir bir ölçek olduğu sonucuna varılmıştır. Daha önce üçüncü yaş turizmine yönelik bir algı ölçeğinin geliştirilmemiş olmasından dolayı yapılan bu çalışmanın literatüre katkı sağlayacağı düşünülmektedir.
Meta-analysis of Photometric and Asteroseismic Measurements of Stellar Rotation Periods: The Lomb–Scargle Periodogram, Autocorrelation Function, and Wavelet and Rotational Splitting Analysis for 92 Kepler Asteroseismic Targets
Authors: Lu 卢 Yuting 鈺婷 , Benomar Othman , Kamiaka 上赤 Shoya 翔也 , Suto Yasushi 
Published: December 2022

Abstract
We perform intensity variability analyses (photometric analyses: the Lomb–Scargle periodogram, autocorrelation, and wavelet) and asteroseismic analysis of 92 Kepler solar-like main-sequence stars to understand the reliability of the measured stellar rotation periods. We focus on the 70 stars without reported stellar companions, and classify them into four groups according to the quarter-to-quarter variance of the Lomb–Scargle period and the precision of the asteroseismic period. We present detailed individual comparison among photometric and asteroseismic constraints for these stars. We find that most of our targets exhibit significant quarter-to-quarter variances in the photometric periods, suggesting that the photometrically estimated period should be regarded as a simplified characterization of the true stellar rotation period, especially under the presence of the latitudinal differential rotation. On the other hand, there are a fraction of stars with a relatively small quarter-to-quarter variance in the photometric periods, most of which have consistent values for asteroseismically and photometrically estimated rotation periods. We also identify over 10 stars whose photometric and asteroseismic periods significantly disagree, which would be potentially interesting targets for further individual investigations.