bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integrating Widely Targeted Lipidomics and Transcriptomics Unravels Aberrant Lipid Metabolism and Identifies Potential Biomarkers of Food Allergies in Rats
Authors: Sun Shanfeng , Li Kexin , Du Hang , Luo Jiangzuo , Jiang Yuchi , Wang Junjuan , Liu Manman , Liu Guirong , Han Shiwen , Che Huilian 
Published: April 2023

ScopeOral food challenges (OFCs) are currently the gold standard for determining the clinical reactivity of food allergy (FA) but are time‐consuming, expensive, and risky. To screen novel peripheral biomarkers of FA and characterize the aberrant lipid metabolism in serum, 24 rats are divided into four groups: peanut, milk, and shrimp allergy (PA, MA, and SA, respectively) and control groups, with six rats in each group, and used for widely targeted lipidomics and transcriptomics analysis.Methods and resultsWidely targeted lipidomics reveal 144, 162, and 206 differentially accumulated lipids in PA, MA, and SA groups, respectively. The study integrates widely targeted lipidomics and transcriptomics and identifies abnormal lipid metabolism correlated with widespread differential accumulation of diverse lipids (including triacylglycerol, diacylglycerol, sphingolipid, and glycerophospholipid) in PA, MA, and SA. Simplified random forest classifier is constructed through five repetitions of 10‐fold cross‐validation to distinguish allergy from control. A subset of 15 lipids as potential biomarkers allows for more reliable and more accurate prediction of FA. Independent replication validates the reproducibility of potential biomarkers.ConclusionThe results reveal the major abnormalities in lipid metabolism and suggest the potential role of lipids as novel molecular signatures for FA.
One‐dimensional nonlinear creep consolidation of soft soils with time‐dependent drainage boundary under construction load
Authors: Cui Penglu , Cao Wengui , Liu Yangyang , Zhang Xingyi , Li Huixin , Xu Zan 
Published: April 2023

AbstractTo further investigate the nonlinear creep properties of soft soils and the effect of variable loading, a one‐dimensional (1D) nonlinear creep consolidation system of soft soils under construction load is established, including time‐dependent drainage (TDD) boundary, elastic‐viscous‐plastic deformation, non‐Darcy flow (NDF), and self‐weight stress. The consolidation problem is presented by virtue of the finite volume method, and the associated calculation program is compiled. The efficiency of the numerical solutions is validated by comparing the degenerated solution against analytical, semi‐analytical, and numerical solutions. Then the influences of construction load and nonlinear creep model parameters on consolidation are studied. The results show that TDD boundary and construction load significantly affect consolidation, and the larger the loading rate and interface parameter, the faster soil's overall dissipation process of excess pore‐water pressure (EPP). Meanwhile, at the earlier consolidation stage, considering the secondary consolidation effect will cause an increase in excess pore‐water pressure (EPP). Prolonging the construction period, decreasing the interface parameter, considering the self‐weight stress, or increasing the non‐Newtonian index will all aggravate this phenomenon. Additionally, the TDD boundary, construction load, and non‐Newtonian index flow (NNIF) are not a determinant for final soil settlement.
Impact of COVID‐19 in relation to the outpatient pediatric feeding therapy experience: A speech‐language pathologist's review of literature and professional experience
Authors: Theodotou Kyrsten Leigh 
Published: April 2023

AbstractIt is well known in the medical and pediatric feeding community how parental stress affects outcomes of pediatric nutrition and feeding behaviors. There is growing literature suggesting the impact of the COVID‐19 pandemic in relation to caregiver and child stress. It could be suggested that this increase in stress contributed to or exacerbated pediatric feeding difficulties. In addition, the COVID‐19 pandemic resulted in pediatric rehabilitation therapists quickly transitioning from in‐person to virtual evaluation and treatment models. The purpose of this article is to review current literature regarding the definition and prevalence of pediatric feeding disorder, the impact of the COVID‐19 pandemic on parent/child stress and relationships surrounding feeding, and this speech‐language pathologist's perception of both the positive and negative aspects of providing ongoing outpatient feeding evaluations and treatments in the context of the COVID‐19 pandemic, as well as clinical considerations for ongoing feeding therapy after the COVID‐19 pandemic.
Assessing public perception and awareness of UK mandatory calorie labeling in the out‐of‐home sector: Using Twitter and Google trends data
Authors: Polden Megan , Robinson Eric , Jones Andrew 
Published: April 2023

AbstractObjectivesIn 2021 the UK government announced a new obesity policy requiring large out‐of‐home food outlets to provide mandatory in‐store calorie labeling on food and drink items. Public acceptability and engagement with obesity policies could influence the level of impact on wider public health particularly with population‐level policies such as calorie labeling. This study aimed to examine public responses and awareness of the policy using social media (Twitter) comments and Google trends data.MethodsThis study examined responses to social media posts on Twitter (tweets) from the UK Department of Health and Social Care detailing the policy, implementation date and post‐implementation information about the policy's enforcement. The sentiments of the tweets were coded and the number of likes and replies extracted. This study utilized google trends to examine public awareness of the policy by extracting weekly relative search volume for relevant phrases such as “calorie labeling.”ResultsFrom the 276 replies/quote‐tweet extracted, the majority expressed a negative sentiment toward the policy (N = 197/71.4%). There were fewer tweets expressing a positive sentiment (N = 25/8.7%) and a neutral/no sentiment (N = 54/19.6%). There was no difference in the number of “likes” or retweets between tweets expressing positive or negative sentiments. Five themes were identified expressing negative sentiments (most common being negative impacts on eating disorders). Google trends data revealed increased searches for “calorie labels/labeling” during the week of the policy enforcement compared to previous weeks in the last 5 years but no significant differences in searches for specific menu calorie labeling.ConclusionsThis analysis revealed negative sentiment toward and increased searching of calorie labeling information during the announcement and implementation of the 2021 mandatory calorie labeling policy in England. A greater understanding of public responses to calorie labeling policies may help tailor future policies and public communication strategies.
Effectiveness of the forced‐choice coin test for detecting malingering during forensic psychiatric examinations
Authors: Tsuji Keisuke 
Published: April 2023

AbstractBackgroundIn general clinical psychiatric practice, open questions are favored over closed ones because they are considered more therapeutically effective and less likely to make the patients pander to us. However, in forensic psychiatric examinations, suspects may attempt malingering.Case PresentationUsing a simple examination based on a forced‐choice technique, the author proved that the level of intelligence of a theft suspect pretending to have an intellectual developmental disorder was not so low. The author prepared two sets consisting of a few coins each and asked the suspect to choose which set had a higher total value. The suspect was questioned repeatedly over multiple trials. He always selected the wrong set over the course of more than 10 trials.ConclusionIf the suspect really did not know the correct answer, the probability of getting the answer right or wrong in a binary choice question is 50% for both. The probability of answering the question wrong by chance 10 times in a row is (1/2),10in other words, about 0.1%. It was evident that the suspect intentionally kept answering incorrectly. When suspects who pretend to have an intellectual developmental disorder answer only “I do not know” to all questions without actively playing out the symptoms, it is difficult to demonstrate that the symptoms are psychiatrically conflicting and prove that they are malingering. Even in such cases, this type of test based on a forced‐choice technique can be used to prove that suspects are behaving falsely.
Oral health and cystic fibrosis in pediatrics: A survey of health professionals
Authors: Chin Delia , Ramalingam Lochana , Harrison Joanne , Silva Mihiri 
Published: April 2023

AbstractBackgroundChildren with cystic fibrosis (CF) are usually managed by hospital‐based, multidisciplinary teams (MDTs). This study aimed to investigate oral health perspectives, training, and practices of health professionals working with children with CF.MethodsData were collected through an online survey distributed to health professionals caring for children with CF by the CF Director in 12 Australian hospitals. The questions related to perspectives, training, and dental referral/advice relating to oral health for children with CF. The data were analyzed using descriptive statistics.ResultsForty‐four participants (26 physicians, 8 nurses, 6 physiotherapists, 2 dieticians, 1 psychologist, and 1 pharmacist) completed the survey. Most (n = 33, 75%) indicated they rarely/never check or discuss dental health. Of those who did, most reported lacking skills to inspect teeth and discuss dental health. Frequently reported barriers were lack of skills, training, knowledge, and time. Most respondents (n = 30, 68%) indicated they rarely/never recommend patients to see the dentist. The most frequently reported barrier to referrals was not considering it part of their role (43%).ConclusionsCloser working relations between CF units and dental teams may remove barriers that prevent non‐dental clinicians from supporting patients with CF maintain oral health. Better integration of dental care within the MDT through improved professional training, increased referral practices, and availability of digital resources may help to improve dental care for all children, including children and adolescents with CF.
Direct analysis in real‐time mass spectrometry: Observations of helium, nitrogen and argon as ionisation gas for the detection of small molecules using a single quadrupole instrument
Authors: Mathias Simone , Sears Patrick 
Published: April 2023

RationaleDirect analysis in real time is typically performed using helium as the ionisation gas for the detection of analytes by mass spectrometry (MS). Nitrogen and argon are found with abundance in the air and provide a cheaper and greener alternative to the use of helium as ionisation gas. This study explores the use of helium, nitrogen and argon as ionisation gas for the detection of organic compounds.MethodsFour illicit drugs, two amino acids and five explosives were chosen as target analytes to understand selectivity, sensitivity and linearity when helium, nitrogen or argon was used as the ionisation gas with the direct analysis in real time (DART) source. Analysis was carried out on a Waters Acquity QDa single quadrupole mass spectrometer.ResultsCalibration curves over the range of 5–100 ng were produced for each analyte using the different ionisation gases to assess the instrument response. Nitrogen gave a higher response to concentration than helium or argon; however, the lowest limits of detection were observed when helium was used.ConclusionsAll the target analytes were detected using DART‐MS with helium, nitrogen or argon as the ionisation gas. Whereas helium provided the highest sensitivity, nitrogen produced reasonable limits of detection and had good linearity across the concentration range explored, suggesting it provides a greener and cheaper alternative to helium.
Analyzing the influence of changes in land use and management practices on the lag time of peak flows for tropical watersheds of Ethiopia
Authors: Sultan Dagnenet , Tsunekawa Atsushi , Tsubo Mitsuru , Haregeweyn Nigussie , Adgo Enyew , Meshesha Derege Tsegaye , Berihun Mulatu Liyew , Fenta Ayele Almaw , Ebabu Kindiye , Setargie Tadesual Asamin 
Published: April 2023

AbstractChanges in peak flow response time governed by rainfall and physical configurations of watersheds have been the topic of many studies, but other factors are also important. We aimed to analyze the dynamics in the lag time (TL) of peak flow for a tropical watershed (Kecha) and its sub‐watersheds (Dokmit, Zenjero Maderia, and Wotit Minch) in Ethiopia, as influenced by land‐use changes from 1982 to 2017 and the implementation of soil and water conservation (SWC) practices since 2011. Layered maps of land use, soil type, and SWC practices were used to determine the curve number, and the Natural Resource Conservation Service hydrologic model was used to estimate TL. We compared the estimated values against measured median values of TL for 30 rainfall–runoff events. The estimated TL of 1982, 2005, and 2017 varied from 9 to 19 min, 8 to 18 min, and 10 to 22 min, respectively, in the Dokmit, Zenjero Maderia, and Wotit Minch sub‐watersheds. The smallest (8 min) and greatest (22 min) values of TL were observed during 2005 and 2017, respectively. These results are likely attributable to the increased amount of cultivated area at the expense of bushland and forest in 2005 as compared to 1982, and the implementation of SWC practices in 2011–2017. Dokmit had the lowest TL values of the three sub‐watersheds, most likely because of its greater coverage of grazing and cultivated lands and degraded Nitic Luvisol. The variation in TL values among the sub‐watersheds was related to changes in both land use and SWC practices but also to the presence of degraded areas inherited from past human activities. Overall, such spatiotemporal flow response time analysis can provide useful information for the proper design of sustainable development strategies for particular niches in tropical regions of Ethiopia and elsewhere.
Moderate deviations in cycle count
Authors: Neeman Joe , Radin Charles , Sadun Lorenzo 
Published: April 2023

AbstractWe prove moderate deviations bounds for the lower tail of the number of odd cycles in a random graph. We show that the probability of decreasing triangle density by , is whenever . These complement results of Goldschmidt, Griffiths, and Scott, who showed that for , the probability is . That is, deviations of order smaller than behave like small deviations, and deviations of order larger than behave like large deviations. We conjecture that a sharp change between the two regimes occurs for deviations of size , which we associate with a single large negative eigenvalue of the adjacency matrix becoming responsible for almost all of the cycle deficit. We give analogous results for the ‐cycle density, for all odd . Our results can be interpreted as finite size effects in phase transitions in constrained random graphs.
The business case for sustainability reporting in SMEs: consultants' and academics' perceptions
Authors: Castilla‐Polo Francisca , Guerrero‐Baena M. Dolores 
Published: April 2023

AbstractThe main aim of this paper is to provide insights into how the business case for sustainability reporting (SR) in SMEs is perceived by two groups of experts (consultants and academics). In particular, we examine how these two groups prioritize a set of costs and benefits associated with this type of reporting. The study draws on the best–worst method, a multicriteria decision‐making technique. Interviews were conducted with consultants and academics to gather detailed information about their perceptions regarding the costs and benefits that may be derived from the implementation of SR in SMEs. Consultants identified “competitive advantage” and “reputation and legitimacy” as the most relevant potential benefits of implementing SR in SMEs, while academics identified the “economic cost” as the most important criterion to be considered in the decision‐making process. Experts' perceptions of the business case for sustainability may encourage nonreporting SMEs to engage in sustainability. The identified gap between consultants and academics in the prioritization of costs and benefits is especially relevant to the emerging field of SR in SMEs. The study addresses an important topic from across the social and environmental accounting literature, the business case for SR in SMEs.
Tunable Molecular Electrodes for Bistable Polarization Screening
Authors: Spasojevic Irena , Santiso José , Caicedo José Manuel , Catalan Gustau , Domingo Neus 
Published: April 2023

AbstractThe polar discontinuity at any ferroelectric surface creates a depolarizing field that must be screened for the polarization to be stable. In capacitors, screening is done by the electrodes, while in bare ferroelectric surfaces it is typically accomplished by atmospheric adsorbates. Although chemisorbed species can have even better screening efficiency than conventional electrodes, they are subject to unpredictable environmental fluctuations and, moreover, dominant charged species favor one polarity over the opposite. This paper proposes a new screening concept, namely surface functionalization with resonance‐hybrid molecules, which combines the predictability and bipolarity of conventional electrodes with the screening efficiency of adsorbates. Thin films of barium titanate (BaTiO3) coated with resonant para‐aminobenzoic acid (pABA) display increased coercivity for both signs of ferroelectric polarization irrespective of the molecular layer thickness, thanks to the ability of these molecules to swap between different electronic configurations and adapt their surface charge density to the screening needs of the ferroelectric underneath. Because electron delocalization is only in the vertical direction, unlike conventional metals, chemical electrodes allow writing localized domains of different polarity underneath the same electrode. In addition, hybrid capacitors composed of graphene/pABA/ferroelectric have been made with enhanced coercivity compared to pure graphene‐electode capacitors.
A blockchain‐based privacy‐preserving advertising attribution architecture: Requirements, design, and a prototype implementation
Authors: Liu Yang , Lin Liangjie , Jiang Lin , Zhang Weizhe , Wang Xuan , Gheisari Mehdi , Gong Tao , Gao Chao , Najafabadi Hamid Esmaeili 
Published: April 2023

AbstractIn the era of digital marketing, advertisements have become an indispensable part. One of the central challenges is advertising attribution which explains the amount of contribution every publisher has with the conversions. However, through observation, we have found that current advertising platforms attribution, advertisers attribution, or third‐party platforms attribution all have the problems of trust, data leakage, and data forgery. To fill the gap, our work's main contribution is combining blockchain with advertising attribution to propose an architecture for improving the privacy‐preserving degree and amount. In the proposed architecture, publishers, and advertisers can store real‐time data on a blockchain. The attribution results are credible because blockchain is decentralized, tamper‐proof, and traceable. We combine privacy set intersection and zero‐knowledge proof technology to increase the privacy of flowing data. In addition, we describe a preliminary prototype in which publishers, advertisers, and advertising platforms can get the corresponding attribution details. To show its effectiveness, we analyze it from different perspectives, including communication cost, attribution accuracy, and time cost. The results show that our communication cost has significantly reduced compared to the recent studies.
Typification of three Linnaean names in the Byttnerioideae (Malvaceae)
Authors: Dorr Laurence J. 
Published: April 2023

AbstractTypes are designated for the names of three species of Byttnerioideae (Malvaceae) described by Linnaeus. These include lectotypes for the names Hermannia triphylla and Melochia supina (= M. corchorifolia), and a neotype for the name Theobroma augustum (≡ Abroma augustum). Two of the type designations are illustrations and one is a specimen. The identity of H. triphylla has long been uncertain but the lectotype designated here fixes the name as a species of papilionoid legume, which reflects current usage, and a new combination in Lotononis (Fabaceae) is proposed.
Enzymatic hydrolysis extraction and quality assessment of fish oil from Patin catfish (Pangasius Hypophthalmus)
Authors: Indera Nur Izzaidah Muhammad , Iberahim Nur Izzati , Lutpi Nabilah Aminah , Dahalan Farrah Aini , Hamdzah Myzairah 
Published: April 2023

AbstractThis study aimed to characterize the extraction of fish oil and investigate the oil quality of Patin catfish (Pangasius hypophthalmus) using the enzymatic hydrolysis technique. The selected parameters were the concentration of enzymes, temperature, and reaction time. Patin catfish available across Southeast Asia is one of the species most accessible to fast‐growing Malaysian population and one of the most convenient food supply alternatives. In this research, alcalase was used as the source of enzyme to obtain the oil yield percentage. The optimization of the recovery process of Patin catfish oil using enzymatic hydrolysis technique was conducted using the multifactor experiments software Design of Experiments (DoE), which obtained an optimum condition for the oil yield percentage at 55.3°C with a 1.2% enzyme concentration for 3 h. The percentage of oil yield obtained was 10.90%. The fish oil was further characterized via the FTIR spectroscopy analysis at 4000–700 cm−1. The investigation of the oil quality was conducted based on analysis test. The acid value test gives 2.24 mg KOH/g, peroxide with 4 meq/kg, and p‐anisidine analysis leads to 0.895.