bluuebunny/crossref_metadata_2025_split huggingface dataset:
Experience and coping strategies of bowel dysfunction in postoperative patients with rectal cancer: a systematic review of qualitative evidence
Authors: Yanting Zhang , Xv Dandan , Long Wenjia , Wang Jingyi , Tang Chen , Feng Maohui , Li Xuanfei , Wang Bei , Zhong Jun 
Published: March 2023

Aim
Due to the changes of bowel physiological structure and functional disorders after rectal cancer surgery, patients will face many bowel dysfunction for a long time, which will greatly affect their quality of life. The purpose of this review is to integrate the qualitative research on the experience of bowel dysfunction and coping strategies in postoperative patients with rectal cancer.

Methods
Systematic retrieval of PubMed, EMbase, Cochrane Library, CINAHL, Web of Sciences, PsycINFO, Willey and other databases was carried out by using the method of subject words and keywords. The Critical Appraisal Skill Programme (CASP) Qualitative Studies Checklist was used for Qualitative assessment. The findings were extracted from the included study and synthesized into the final themes, which was evaluated strictly in accordance with the ConQual process.

Results
Nine studies involving 345 participants were included and two main themes were extracted: “Experience a series of changes caused by bowel dysfunction” and “nmet needs and coping strategies facing bowel dysfunction”. The changes of rectal cancer patients who experience bowel dysfunction after operation mainly include three parts: bowel dysfunction is more than just a bowel reaction, which covers the bowel symptoms themselves and the subsequent body-related symptoms. The interruption of a normal life, mainly reflected in personal, family, and social life. Complex psychological reactions to bowel dysfunction, psychological changes have a dual nature, showing a positive and negative intertwined. There are two main aspects of unmet needs and coping strategies: the demand is mainly manifested in the need for information and support from medical professionals, while the coping strategy mainly includes diet, activity and drug management.

Conclusion
Rectal cancer patient often experience persistent bowel dysfunction after operation, which has a certain physical and mental effects. A series of new needs of postoperative patients are often not fully met, and patients often rely on their own empirical attempts to seek balance, less can get professional support. Future studies need to focus on how to provide continuous information support for postoperative rectal cancer patients, especially professional care from health care staff.
Baseline gene expression in subcutaneous adipose tissue predicts diet-induced weight loss in individuals with obesity
Authors: Oghabian Ali , van der Kolk Birgitta W. , Marttinen Pekka , Valsesia Armand , Langin Dominique , Saris W. H. , Astrup Arne , Blaak Ellen E. , Pietiläinen Kirsi H. 
Published: March 2023

Background
Weight loss effectively reduces cardiometabolic health risks among people with overweight and obesity, but inter-individual variability in weight loss maintenance is large. Here we studied whether baseline gene expression in subcutaneous adipose tissue predicts diet-induced weight loss success.

Methods
Within the 8-month multicenter dietary intervention study DiOGenes, we classified a low weight-losers (low-WL) group and a high-WL group based on median weight loss percentage (9.9%) from 281 individuals. Using RNA sequencing, we identified the significantly differentially expressed genes between high-WL and low-WL at baseline and their enriched pathways. We used this information together with support vector machines with linear kernel to build classifier models that predict the weight loss classes.

Results
Prediction models based on a selection of genes that are associated with the discovered pathways ‘lipid metabolism’ (max AUC = 0.74, 95% CI [0.62–0.86]) and ‘response to virus’ (max AUC = 0.72, 95% CI [0.61–0.83]) predicted the weight-loss classes high-WL/low-WL significantly better than models based on randomly selected genes (P < 0.01). The performance of the models based on ‘response to virus’ genes is highly dependent on those genes that are also associated with lipid metabolism. Incorporation of baseline clinical factors into these models did not noticeably enhance the model performance in most of the runs. This study demonstrates that baseline adipose tissue gene expression data, together with supervised machine learning, facilitates the characterization of the determinants of successful weight loss.
PROCESSOS DE RESISTÊNCIA E DE EXISTÊNCIA DE NEGROS AMAZÔNICOS: UM PARALELO ENTRE OS SUJEITOS DO MARABAIXO E DO ALTO DO BODE
Authors: Tartaglia Ednaldo 
Published: March 2023

O objetivo deste artigo foi o de visibilizar duas micro-histórias de sujeitos negros amazônicos, para tentar compreender por que, na atualidade, ainda circulam dizeres ofensivos, racistas e opressores sobre determinado corpo social negro. Destacamos alguns acontecimentos os quais uma parcela dos corpos sociais regionais, o Estado e, em alguns casos, também a Igreja Católica lançaram dizeres e ações agressivas contra os sujeitos negros praticantes do Ciclo do Marabaixo, em Macapá-AP, bem como sobre os imigrantes antilhanos no morro Alto do Bode em Porto Velho-RO, ao longo do século XX. Nossa análise se inscreve no campo teórico e metodológico dos Estudos Discursivos Foucaultianos e mobilizamos, para as nossas discussões, especialmente, os conceitos de discurso, poder, resistência, corpo utópico e heterotopia a partir dos trabalhos de Michel Foucault (2003, 2005, 2011, 2013a, 2013b). Aplicamos esses termos conceituais em materialidades discursivas diversas, oriundas de matéria jornalística, redes sociais, livros e trabalhos acadêmicos. A análise possibilita compreender, mas não a aceitar, os discursos preconceituosos que, na contemporaneidade, ainda são lançados sobre determinados sujeitos.
Palavras-chave: Discurso. Sujeito negro amazônico. Marabaixo. Alto do Bode.
Business Plan and Implementation Report on Culinary Business “Rendang Ratu”
Authors: Rasyid Ratu Fathia , Roostika Ratna 
Published: March 2023

This paper was created with the aim to comparing the results of Rendang Ratu business implementation with the planning that had been previously designed in 2022. This business was created by considering the average data on beef consumption by Indonesian people, which tended to be static in the last five years from 2015 to 2021, so that impact on the low animal protein intake in the society, especially for the middle to lower economic class. However, animal protein from meat is an excellent food source for human growth, where this protein complements amino acids that are primary needs as well as the nutritional investment in maintaining long-term health. From this condition, the high demand for meat consumption has shown an opportunity to develop a business in avoiding the fluctuating price of meat and also increase the amount of meat consumption in Indonesia, especially in traditional Indonesian meat dishes. Rendang is a traditional Minang dish made with meat. Rendang Ratu is a Food and Beverage business specializing in processed meat products made with original-natural West Sumatra spices. For this reason, the methodology used is to look at the results of the business design, whether it is realized well or comes up with differences during the implementation process.
Furthermore, the differences found become objects resolved by referring to marketing management theories. The results of this business implementation are well realized, although several gaps have been resolved with solutions referring to marketing management theories. Henceforth, based on the results of observations and existing opportunities, the business development will be formed by expanding product services by providing other processed meats. Thus, the products produced can be more varied, and the target market can be more expansive.
Influence of Hydrogel and Different Sowing Methods on Growth and Yield Aerobic Rice (Oryza sativa L.)
Authors: Saini Rahul , Umesha C. 
Published: March 2023

The field experiment was conducted during Khairf 2022 at Crop Research Farm, Department of Agronomy, SHUATS, Prayagraj (U.P).To evaluatedo the influence of different level Hydrogel (0, 2, 4 kg/ha.) and methods of sowing( on growth and yield of aerobic rice. Hydrogel was broadcasting in the field before sowing (Flatbed sowing. Ridge sowing, furrow sowing) mixed well in the soil. The experiment was laid out in randomized block design and comprised of levels of hydrogel and methods of sowing with ten treatments and each were replicated thrice. The growth attributes which was plant height (96.20 cm), total tillers/m2 (540.27), plant dry weight (1078.70 g/m2), and crop growth rate (65.27 g/m2/day) was significantly increased with increasing the level of Hydrogel (0, 2 to 4 kg/ha.) and maximum was obtained with application of 4 kg Hydrogel with Furrow sowing. The yield attributes was obtained highest effective tillers/m2 (238.33), number of filled grains/panicle (172.83), grain yield (4.81 t/ha), Harvest index (44.35%), gross return (INR 1,76,043/ha), net return (INR 1,31,193/ha.) and benefit cost ratio (2.93).
Multiple-Level Retrolaminar Block can Provide Effective Analgesia in Nipple-Sparing Mastectomy with Latissimus Dorsi Flap Reconstruction: A Report of Two Cases
Authors: Aoki Hiroshi , Terao Yoshiaki , Fujimoto Ekuko , Oji Makito , Oji Natsuko , Iwanaga Hiroki , Hara Tetsuya 
Published: March 2023

Aims: Nipple-sparing mastectomy with latissimus dorsi flap reconstruction (NMLR) may cause moderate to severe postoperative pain. Herein, two cases in which multiple-level RLB injections provided good analgesia for two patients who underwent NMLR are reported. Thoracic paravertebral block (TPVB) is recommended as the first-line regional analgesic technique for breast cancer surgery. Multiple-level TPVBs may provide effective analgesia for NMLR but may increase the risk of complications. A retrolaminar block (RLB), a known alternative to a TPVB, has a lower risk of complications and multiple-level RLB injections may be safely performed.
Presentation of Cases: NMLR was planned for two patients with breast cancer. Multiple-level RLB injections were administered for postoperative pain management. In both cases, the numerical rating scale scores measured at rest were low postoperatively, suggesting that multiple-level RLB injections effectively managed postoperative pain. Adequate analgesia was achieved using multiple-level RLB injections without additional drug administration in both patients.
Discussion and Conclusion: Multiple-level RLB injections may be widely used as appropriate dosages of local anesthetics are considered.
Three Bronze Age burials from Angus
Authors: Sherriff John R 
Published: March 2023

Since October 1980 the author has dealt with three Early/Middle Bronze Age burials whilst employed on Manpower Services Projects sponsored by Angus District Council. The discovery of a short cist at Mains of Melgund, near Aberlemno, by farmworkers who searched the grave in April 1980 produced a jet necklace, a flint scraper and the remains of an inhumation. The author re-excavated the cist in October 1980. In February 1982 the author visited the site of a cairn on Baldardo Farm, Forfar, and found that recent ploughing had dislodged the capstone of a short cist. Subsequent excavation produced the cremated remains of a young adult and a flint knife. Probable Beaker sherds and a quantity of burnt bone lay on the N side of the grave and perhaps hint at a re-use of the cist. In June 1982 a small round cairn was excavated by the author on Easter Marcus Farm near Finavon. The site had been disturbed by the ploughing of previous pasture and excavation showed that the cairn covered a spread of dark soil, sherds of cinerary urn, burnt bone and charcoal.
The excavation of a Mesolithic horizon at 13-24 Castle Street, Inverness
Authors: Wordsworth Jonathan , Bradley Rosemary , Dickson Camilla , Harman Mary , Máté I , Harden Gillian 
Published: March 2023

A microlithic flint industry dating to c 5000 be was found, containing 137 retouched pieces and 4700 other fragments. No structures were identified. The occupation level in which the flints were found was sealed by a complex soil horizon that included two marine transgressions.
The procurement and use of stone for flaked tools in prehistoric Scotland
Authors: Wickham-Jones Caroline R 
Published: March 2023

Throughout prehistory a wide variety of stones have provided the raw material for the manufacture of flaked tools. In western Europe, however, the abundance of fine quality, nodular flint led to its dominance as a lithic
resource with the result that modern archaeological attention in this area has concentrated upon the use of flint in prehistory, often to the exclusion of anything else.

Scotland lacks any primary sources of flint nodules in situ and there is no evidence that flint was imported on any scale, although well-developed exchange networks have been documented elsewhere in Europe (Balcer 1981). A wide variety of alternative materials were available in Scotland but this traditional preoccupation with flint as a raw material has meant that, until recently, they were given little attention and Scottish assemblages were regarded as somewhat impoverished. Increasing awareness of this variety has improved the recovery by
excavation of lithic assemblages and their subsequent analysis.

Such analysis poses its own problems. Knapping techniques may produce different detachment characteristics upon different raw materials and the development of regional comparisons is not as straightforward as in areas where only one, homogeneous, source of flint was utilized. As techniques develop, however, the variety of methods employed to utilize lithic resources is revealed and a sophisticated pattern of exploitation throughout prehistoric Scotland is emerging.
Self‐Powered Syringe Pump for Insulin Pump Therapy Based on High‐Voltage Triboelectric Nanogenerator and Dielectric Elastomer Actuator
Authors: Wei Yi , Wu Wenjie , Wang Yuhao , Chen Xiangyu , Wang Zhong Lin , Yang Dan 
Published: March 2023

AbstractInsulin pump therapy (IPT) is commonly utilized for treating type 1 diabetes. However, the insulin pump is generally rigid, and its prolonged use can cause discomfort to patients. Additionally, the device suffers from other drawbacks such as limited battery life. Herein, an IPT system consisting of a dielectric elastomer‐based soft syringe pump (DE‐SSP) and a high‐voltage triboelectric nanogenerator (H‐TENG) is introduced, which can achieve stable and adjustable liquid output depending on real‐time blood glucose. The maximum pump volume of this IPT can reach 262.4 or 303.7 µL when powered by a DC source or H‐TENG, respectively, which is generally sufficient to meet the requirements of the therapy. H‐TENG possesses a sensitive self‐protection mechanism that minimizes the risk of electrical damage and it can be easily fabricated or repaired and flexibly designed according to the application environment. The proposed IPT system is compatible with different placement angles and utilizes compliant electrodes with good biocompatibility that ensure its safety. It also overcomes common issues including rigidness, relatively fixed bolus delivery options, and short battery life associated with traditional insulin pumps. This study not only demonstrates a combination of H‐TENG and DE‐based actuators but also opens new avenues for microelectromechanical systems micropumps.
Brightening Blue Photoluminescence in Nonemission MOF‐2 by Pressure Treatment Engineering
Authors: Zhang Ting , Yong Xue , Yu Jingkun , Wang Yixuan , Wu Min , Yang Qing , Hou Xuyuan , Liu Zhaodong , Wang Kai , Yang Xinyi , Lu Siyu , Zou Bo 
Published: March 2023

AbstractAs equally essential as the synthesis of new materials, maneuvering new structure configurations can endow the brand‐new functional properties to existing materials, which is also one of the core goals in the synthesis community. In this respect, pressure‐induced emission (PIE) that triggers photoluminescence (PL) in nonemission materials is an emerging stimuli‐responsive smart materials technology. In the PIE paradigms, harvesting bright PL at ambient conditions, however, has remained elusive. Herein, a remarkable PIE phenomenon is reported in initially nonemission Zn(BDC)(DMF)(H2O) (MOF‐2), which shows bright blue‐emission at 455 nm under pressure. Intriguingly, the bright blue PL with an excellent photoluminescence quantum yield up to 70.4% is unprecedentedly retained to ambient conditions upon decompression from 16.2 GPa. The detailed structural analyses combined with density functional theory calculations reveal that hydrogen bonding cooperativity effect elevates powerfully the rotational barrier of the linker rotor to 3.87 eV mol−1 from initial 0.91 eV mol−1 through pressure treatment. The downgrade rotational freedom turns on PL of MOF‐2 after releasing pressure completely. This is the first case of harvesting PIE to ambient conditions. These findings offer a new platform for the creation of promising alternatives to high‐performance PL materials based on initially nonemission counterparts.
Porous Metal–Organic Framework/ReS2 Heterojunction Phototransistor for Polarization‐Sensitive Visual Adaptation Emulation
Authors: Xie Dingdong , Gao Ge , Tian Bobo , Shu Zhiwen , Duan Huigao , Zhao Wei‐Wei , He Jun , Jiang Jie 
Published: March 2023

AbstractVisual adaptation allows organisms to accurately perceive the external world even in dramatically changing environments, from dim starlight to bright sunlight. In particular, polarization‐sensitive visual adaptation can effectively process the polarized visual information that is ubiquitous in nature. However, such an intriguing characteristic still remains a great challenge in semiconductor devices. Herein, a novel porous metal–organic‐framework phototransistor with anisotropic‐ReS2‐based heterojunction is demonstrated for polarization‐sensitive visual adaptation emulation. The device exhibits intriguing polarized sensitivity and an adaptive ability due to its strong anisotropic and trapping–detrapping characteristics, respectively. A series of polarization‐sensitive neuromorphic behaviors like polarization‐perceptual excitatory postsynaptic current, multimode adjustable dichroic ratio and reconfigurable sensory adaption, are experimentally demonstrated through this porous heterojunction phototransistor. More importantly, with the polarization–electricity cooperation strategy, advanced polarization‐sensitive visual adaptation with strong bottom‐gate control and environment dependence is successfully realized. These results represent a significant step toward the new generation of intelligent visual perception systems in autonomous navigation and human–machine interaction, etc.
A Ritter‐Type Route to Diarylmethane Amides from para‐Quinone Methides
Authors: Akyildiz Volkan , Saracoglu Nurullah 
Published: March 2023

Abstract1,6‐Conjugate addition/Ritter‐type amidation of para‐quinone methides (p‐QMs) with nitriles is described. This transformation is an environmentally friendly approach by the use of NaHSO4 as a low‐loading, inexpensive, green, and recyclable catalyst. Diarylmethane amides are afforded in excellent yields through a one‐pot process from p‐QMs and nitrile derivatives under mild reaction conditions.
The Ruskin Speech and Great Debate in English education, 1976–1979: A study of motivation
Authors: Silverwood James , Wolstencroft Peter 
Published: March 2023

AbstractJames Callaghan's speech at Ruskin College, Oxford in October 1976 is widely considered a pivotal moment in modern English educational policy. Whilst it is not our intention to challenge this fundamental point, the paper will critically interrogate some long‐held assumptions about the motivation that led Callaghan to deliver his speech at Ruskin College. Specifically, the paper will argue that the Ruskin Speech, which spawned a subsequent great debate on education, was motivated by a desire to protect and support comprehensive education, rather than generate more fundamental and radical educational reform away from those principles. Where successive governments have referred back to the ideals espoused by the speech as justification for subsequent educational transformation away from comprehensive ideals, this has only served to imbue the Ruskin Speech and Great Debate with motivations that were not shared at the time by Callaghan and his Labour government.
Visualizing Pollution: Representations of Biological Data in Water Pollution Control in the United States, 1948–1962
Authors: Hearty Ryan 
Published: March 2023

AbstractAfter the United States Congress passed the Water Pollution Control Act of 1948, biologists played an increasingly significant role in scientific studies of water pollution. Biologists interacted with other experts, notably engineers, who managed the public agencies devoted to water pollution control. Although biologists were at first marginalized within these agencies, the situation began to change by the early 1960s. Biological data became an integral part of water pollution control. While changing societal values, stimulated by an emerging ecological awareness, may explain broader shifts in expert opinion during the 1960s, this article explores how graphs changed experts’ perceptions of water pollution. Experts communicated with each other via reports, journal articles, and conference speeches. Those sources reveal that biologists began experimenting with new graphical methods to simplify the complex ecological data they collected from the field. Biologists, I argue, followed the engineers’ lead by developing graphical methods that were concise and quantitative. Their need to collaborate with engineers forced them to communicate, negotiate, and overcome conflicts and misunderstandings. By meeting engineers’ expectations and promoting the value of their data through images as much as words, biologists asserted their authority within water pollution control by the early 1960s.
miR96‐ and miR182‐driven regulation of cytoskeleton results in inhibition of glioblastoma motility
Authors: Akdaş Enes Yağız , Temizci Benan , Karabay Arzu 
Published: March 2023

AbstractGlioblastoma multiforme (GBM) is one of the most common forms of brain tumor. As an excessively invasive tumor type, GBM cannot be fully cured due to its invasion ability into healthy brain tissues. Therefore, molecular mechanisms behind GBM migration and invasion need to be deeply investigated for the development of effective GBM treatments. Cellular motility and invasion are strictly associated with the cytoskeleton, especially with actins and tubulins. Palladin, an actin‐binding protein, tightly bundles actins during initial invadopodia and contraction fiber formations, which are essential for cellular motility. Spastin, a microtubule‐binding protein, cuts microtubules into small pieces and acts on invadopodia elongation and cellular trafficking of invadopodia‐associated proteins. Regulation of proteins such as spastin and palladin involved in dynamic reorganization of the cytoskeleton, are rapidly carried out by microRNAs at the posttranscriptional level. Therefore, determining possible regulatory miRNAs of spastin and palladin is critical to elucidate GBM motility. miR96 and miR182 down‐regulate SPAST and PALLD at both transcript and protein levels. Over‐expression of miR96 and miR182 resulted in inhibition of the motility. However, over‐expression of spastin and palladin induced the motility. Spastin and palladin rescue of miR96‐ or miR182‐transfected U251 MG cells resulted in diminished effects of the miRNAs and rescued the motility. Our results demonstrate that miR96 and miR182 over‐expressions inhibit GBM motility by regulating cytoskeleton through spastin and palladin. These findings suggest that miR96 and miR182 should be investigated in more detail for their potential use in GBM therapy.