bluuebunny/crossref_metadata_2025_split huggingface dataset:
3D simulation of interosseous interference in sagittal split ramus osteotomy for mandibular asymmetry
Authors: Udayakumar Santhiya Iswarya Vinothini , Kim Dohyoung , Choi So-Young , Kwon Tae-Geon 
Published: September 2023

Abstract
Background
The purpose of this study was to evaluate the pattern of predicted interosseous interference and to determine the influencing factor to volume of bony interference using a computer-assisted simulation system. This retrospective study recruited 116 patients with mandibular prognathism who had undergone sagittal split ramus osteotomy (SSRO) with or without maxillary osteotomy. The patients were divided into 3 groups according to the amount of menton (Me) deviation: less than 2 mm (Group 1), 2–4 mm (Group 2), and more than 4 mm (Group 3). Changes in the distal segments following BSSRO and the volume of the interosseous interference between the proximal and distal segments were simulated after matching preoperative occlusion and postoperative expected occlusion with the cone-beam computed tomography data. Ramal inclinations and other skeletal measurements were analyzed before surgery, immediately after surgery, and at least 6 months after surgery.

Results
The anticipated interosseous interference was more frequently noted on the contralateral side of chin deviation (long side) than the deviated site (short side) in Groups 2 and 3. More interference volume was predicted at the long side (186 ± 343.9 mm3) rather than the short side (54.4 ± 124.4 mm3) in Group 3 (p = 0.033). The bilateral difference in the volume of the interosseous interference of the osteotomized mandible was significantly correlated with the Me deviation (r =  − 0.257, p = 0.009) and bilateral ramal inclination (r = 0.361, p < 0.001). The predictor variable that affected the volume of the osseous interference at each side was the amount of Me deviation (p = 0.010).

Conclusion
By using the 3D simulation system, the potential site of bony collision could be visualized and successfully reduced intraoperatively. Since the osseous interference can be existed on any side, unilaterally or bilaterally, 3D surgical simulation is necessary before surgery to predict the osseous interference and improve the ramal inclination.
A new optimal allocation of DGs in distribution networks by using coot bird optimization method
Authors: Memarzadeh Gholamreza , Arabzadeh Mohammadreza , Keynia Farshid 
Published: September 2023

AbstractEnergy is one of the most important topics in the world today and is considered as one of the most effective factors for the development of countries. Due to the limitation of non-renewable energy sources and undesirable effects of consuming these resources on the environment, the strategy of countries has changed towards the use of renewable energy. Renewable energy sources do not decrease over time and operate independently of price fluctuations and are more available, thus being able to play a greater role in modern power systems. Therefore, the optimal location and use of these resources will have an impact on modifying the parameters of the power grid. In this paper an analytical approach for optimal placement and sizing of distributed generation (DG) in power distribution networks to minimize the power loss, bus voltage limits, DG capacity limits, current limits, and DG penetration limit. In the first step, determines the DG capacity causing maximum benefit at different buses, and then selects the best location for DG placement which corresponds to highest benefit in the buses. This method is applicable for sizing and siting of single as well as multiple DG units. The coot bird optimization method (CBOM) is proposed for solving optimal placement, size, and power factor (PF) of DG in distribution network. The suggested method is tested on the IEEE 33-bus, 69-bus, Distribution Networks. The proposed CBOM method has good performance to find optimal placement, size, and PF of DG and it can be applied for various distribution system.
Phosphorylation of axin within biomolecular condensates counteracts its tankyrase-mediated degradation
Authors: Klement Katharina , Brückner Martina , Bernkopf Dominic B. 
Published: September 2023

ABSTRACT
Axin (also known as AXIN1) is a central negative regulator of the proto-oncogenic Wnt/β-catenin signaling pathway, as axin condensates provide a scaffold for the assembly of a multiprotein complex degrading β-catenin. Axin, in turn, is degraded through tankyrase. Consequently, tankyrase small-molecule inhibitors block Wnt signaling by stabilizing axin, revealing potential for cancer therapy. Here, we discovered that axin is phosphorylated by casein kinase 1 alpha 1 (CSNK1A1, also known as CK1α) at an N-terminal casein kinase 1 consensus motif, and that this phosphorylation is antagonized by the catalytic subunit alpha of protein phosphatase 1 (PPP1CA, hereafter referred to as PP1). Axin condensates promoted phosphorylation by enriching CK1α over PP1. Importantly, the phosphorylation took place within the tankyrase-binding site, electrostatically and/or sterically hindering axin–tankyrase interaction, and counteracting tankyrase-mediated degradation of axin. Thus, the presented data propose a novel mechanism regulating axin stability, with implications for Wnt signaling, cancer therapy and self-organization of biomolecular condensates.
Physiological responses to acute warming at the agitation temperature in a temperate shark
Authors: Bouyoucos Ian A. , Weinrauch Alyssa M. , Jeffries Ken M. , Anderson W. Gary 
Published: September 2023

ABSTRACT
Thermal tolerance and associated mechanisms are often tested via the critical thermal maximum (CTmax). The agitation temperature is a recently described thermal limit in fishes that has received little mechanistic evaluation. The present study used a temperate elasmobranch fish to test the hypothesis that this thermal tolerance trait is partially set by the onset of declining cardiorespiratory performance and the cellular stress response. Pacific spiny dogfish (Squalus suckleyi) were screened for cardiorespiratory and whole-organism thermal limits to test for associations between thermal performance and tolerance. Then, biochemical markers of secondary stress, aerobic and anaerobic enzyme activities, and molecular markers of cellular stress were determined for various tissues at the agitation temperature and secondary stress markers were determined at CTmax. In dogfish, the agitation temperature was characterised by increased turning activity within experimental chambers and was equal to the temperature at which dogfish exhibited maximum heart rate. Citrate synthase activity increased at the agitation temperature in white muscle relative to unmanipulated dogfish. Furthermore, lactate dehydrogenase activity and accumulated lactate in the plasma and muscle were not affected by acute warming. Cellular stress was apparent in hypothalamus, gill filament and ventricle, denoted by elevated transcript abundance of the stress response gene hsp70 but not the oxygen homeostasis gene hif1α. Conversely, CTmax was characterised by metabolic acidosis driven by anaerobic lactate production, signifying an increased reliance on anaerobic metabolism between the agitation temperature and CTmax. Together, these data provide partial support for our hypothesis, in that cellular stress, but not declining thermal performance, occurred at the agitation temperature.
Human muscle–tendon unit mechanobiological responses to consecutive high strain cyclic loading
Authors: Epro Gaspar , Suhr Frank , Karamanidis Kiros 
Published: September 2023

ABSTRACT
In response to a mechanical stimulus, tendons have a slower tissue renewal rate compared with muscles. This could, over time, lead to a higher mechanical demand (experienced strain) for the tendon, especially when a high strain magnitude exercise is repeated without sufficient recovery. The current study investigated the adaptive responses of the human triceps surae (TS) muscle–tendon unit (MTU) and extracellular matrix turnover-related biomarkers to repetitive high tendon strain cyclic loading. Eleven young adult males performed a progressive resistance exercise over 12 consecutive days, consisting of high Achilles tendon (AT) strain cyclic loading (90% MVC) with one leg once a day (LegT1) and the alternate leg three times a day (LegT3). Exercise-related changes in TS MTU mechanical properties and serum concentrations of extracellular matrix turnover-related biomarkers were analysed over the intervention period. Both legs demonstrated similar increases in maximal AT force (∼10%) over the 12 day period of exercise. A ∼20% increase in maximal AT strain was found for LegT3 (P&lt;0.05) after 8 consecutive exercise days, along with a corresponding decrease in AT stiffness. These effects were maintained even after a 48 h rest period. The AT mechanical properties for LegT1 were unaltered. Biomarker analysis revealed no sign of inflammation but there was altered collagen turnover and a delay in collagen type I synthesis. Accordingly, we suggest that tendon is vulnerable to frequent high magnitude cyclic mechanical loading as accumulation of micro-damage can potentially exceed the rate of biological repair, leading to increased maximal tendon strain.
PRAGMATIC ASPECTS OF THE QUESTION IN THE ENGLISH ADVERTISING TOURIST NARRATIVE
Authors: Gavrikova Yuliya S. , Golukovich Alla E. , Trushchinskaya Alexandra S. 
Published: September 2023

The article analyzes interrogative sentences in the English advertising tourist narrative. The study is relevant due to the fact that the interrogative sentence has a significant speech potential. This is a reason for opportunities of research. The purpose of the work is to classify interrogative sentences in English advertising texts on the topic of travel, using certain criteria. The use of interrogative sentences is one of the syntactic distinguishing features of English advertising texts. Interrogative sentences intrigue potential buyers, draw their attention to the advertised product or service. The novelty of the study lies in the fact that the question is not studied as a statement taken out of context, on the contrary, the target orientation of interrogative sentences is analyzed. The article reveals the communicative intentions of the questions in the analyzed narrative, and also identifies the types of questions in terms of the communicative intention they carry out. The questions are also compared by the frequency of use in the travel advertising narrative.
Materials and methods. 136 questions were selected by the method of continuous sampling from English-language sites devoted to advertisements for travelling. The contextual method, the method of continuous sampling, distributive, pragmatic and quantitative methods were used in the analysis.
Results. The results of the study showed that the communicative intentions of the questions in the English-language advertising narrative differ from the questions used in dialogic speech. The analysis of communicative intentions made it possible to distinguish three types of questions. They are guiding questions, the purpose of which is to focus the reader’s attention on something special, to encourage some actions; involving questions, the purpose of which is to attract the reader, to motivate them to read the advertisement; preliminary questions, the purpose of which is to simulate a dialogic speech with an expert in the field of tourism. The guiding question is the most frequent type of question in travel advertising narrative. This is due to the fact that the purpose of the advertisement is to encourage certain actions.
Practical implications. The results can be used in further studies of the pragmatic aspects of interrogative sentences in the English-language advertising narrative.
INTERACTION OF THE VLADIMIR GOVERNORS AND LAW ENFORCEMENT AGENCIES IN THE LAST QUARTER OF THE XIX – BEGINNING OF THE XX CENTURIES
Authors: Kudryashov Kirill O. 
Published: September 2023

Background. In the last quarter of the 19th – early 20th century. in the Russian Empire, there was an intensification of the revolutionary and strike movement, as well as the growth of state opposition. To restore order and ensure control, the governors of the regions, including the Vladimir province, were given broader powers in the field of interaction with law enforcement agencies. New structures were created to fight the opposition: the factory police, a network of agents, and others. The article analyzes the effectiveness of interaction between governors and law enforcement agencies, reveals the personnel policy of the provincial government.
The purpose of the article is to study the effectiveness of interaction between the Vladimir governors and law enforcement agencies in the last quarter of the 19th – early 20th centuries.
Materials and methods. The materials for the study were official documents of the State Archives of the Vladimir Region, the State Archives of the Ivanovo Region and the State Archives of the Russian Federation. The methodological basis of this study is the principles of historicism and consistency, implemented thanks to the problem-chronological, historical-genetic and analytical methods.
Results. The article discusses the interaction of the governors of the Vladimir province with law enforcement agencies in problem situations. During the period of growing opposition sentiments, the governors comprehensively resorted to the functions of law enforcement agencies. At the end of XIX – beginning of XX century it was planned to soften the course of the governors in relation to the opposition, they avoided direct intervention. The governors were interested in the protection of law and order in the region. The peculiarity of the work of the provincial government with the personnel of law enforcement agencies is given.
Conclusion. The results of the study can be applied in a regional study of similar “internal” provinces of the Russian Empire on this issue, also for the preparation of manuals and lectures on the relationship of governors and law enforcement agencies.
PECULIARITIES OF SLANGISMS TRANSLATION IN ANNA TODD’S NOVEL «AFTER»
Authors: Sapukh Tatiana V. , Brotsman Dmitry A. 
Published: September 2023

Background. The article is devoted to the study of the peculiarities of the translation of slangisms in Anna Todd’s novel After. The authors define slang as fragile, unstable, non-codified, and often completely random collections of lexemes that exist in the colloquial sphere, reflecting the public consciousness of people belonging to a certain social or professional environment. Slangisms are units of the lexical and phraseological system of slang used in popular oral and written speech. This article compares the translations of the novel After by the modern American writer A. Todd into Russian.
Purpose. The purpose of the article is to study the features of the translation of slangisms on the example of official and unofficial (amateur) translations of A. Todd’s novel After.
Materials and methods. The material of the study is A. Todd’s novel After, its official translation by M. Belyakov and an unofficial translation taken from the Ficbook.com website, performed by an amateur translator. During the study, a set of complementary research methods was used: theoretical analysis of scientific research on the problem, continuous sampling method, analysis and interpretation of the results obtained.
Results. Based on the analysis of the corpus of examples, it was revealed that when translating slangisms in A. Todd’s novel After, such translation techniques as variant correspondence, semantic development, and contextual translation were most often used. When translating slangisms, translators considered such factors as the age, social and personal qualities of the characters, as well as the unique style of the author’s language.
PHILOSOPHY OF HUMAN EXISTENCE IN THE URBANIZED ENVIRONMENT
Authors: Lapshina Valentina S. 
Published: September 2023

The existential and socio-psychological threats to human bodily and emotional existence are observed in the urbanized environment, and the origins of the modern urban crisis are discovered. The author attempts to assess the danger and consequences of urbanization for modern human society. The paper formulates a typology of urban activism in the context of socio-philosophical discourse.
The aim of the research is philosophical comprehension of human existence in an urbanized environment. In accordance with the purpose, the tasks are outlined: to characterize the “city man”; to identify the contradictory consequences of urbanization for a modern Human; to determine the influence of urbanization atpeople’s lifestyle; to analyze the typology of the activities of city residents which(the activities) transform the urban environment in the context of modern urbanism.
Object: urbanism as a socio-philosophical phenomenon, subject: the existential dimension of Human in an urban environment.
Methodology. To achieve this goal, general scientific methods were used: analysis and synthesis, analogies, classifications, as well as philosophical methods of cognition (dialectical and hermeneutic). The method of generalization of philosophical and sociological issueswas applied and in particular by using interdisciplinary approach. The means of visual anthropology (cinematography, photography) are engaged in the study to analyze the documentary series “Homo Urbanus” whichis of special scientific value as a source of important social knowledge.
The originality of the study: the existential crisis was studied in the focus of urban anthropology, a classification of types of urban activism was proposed. Practical application. The results of the study can be applied in the future interdisciplinary research, as well as in the urban anthropology studies, in the research of the mutual influence of the city and man, as well as of separate topics of educational courses (“Urban Studies”, “Philosophy”, “Sociology”, “Anthropology”, “Aesthetics of Architecture and Design”, etc.).
Surgical treatment of the perihilar cholangiocarcinoma with portal vein invasion
Authors: Popov O. 
Published: September 2023

Background. Perichilar cholangiocarcinoma is a rare type of malignant neoplasm and is 3-7 cases per 100,000 population. Surgical method is the only radical method of treatment, allowing to improve long-term survival results. One of the important and characteristic features of perihilar cholangiocarcinoma is tumor invasion to the area of the portal vein bifurcation, which occurs in 30–45% of cases. Portal vein invasion is the one of the main causes of perihilar cholangiocarcinoma irresectability. However, innovative surgical technologies allow resection of the liver with resection and reconstruction of the portal vein with acceptable mortality.
The aim. The aim of our study was to asses results of surgical treatment of perihilar cholangiocarcinoma with (Group 1) and without (Group 2) portal vein invasion.
Materials and methods. From 2003 to January 2023 in the Department of Surgery and Liver Transplantation of the Ukrainian National Institute of Surgery and Transplantation, 208 patients with perihilar cholangiocarcinoma underwent major extended liver resections. We compared 93 (46%) patients who received extended liver resection with portal vein resection (Group 1) with 115 (54%) patients who underwent liver resections without vascular reconstructions (Group 2). The average Ca 19–9 in the group 1 was 288 (8 – 1000) U/ml, in the group 2 –262 (10 – 612) U/ml. The level of total bilirubin in patients of the group 1 was 312 (43 – 621) mcmol/l, in the group 2 – 267 (10 – 612) mcmol/l. In view of this, in the preoperative period, 190 (91,3%) patients underwent decompression of the bile ducts, using percutaneous transhepatic cholangiostomy (PTBD) or retrograde endobiliary stenting. For patients with small remnant liver volume less than 40 %, in 80(38,5%) cases we did preoperative PVE of a resected part of the liver. In 9 cases we made simultaneous PVE and PTBD. When choosing the volume of surgical intervention, we proceeded from the tumor type of Bismuth-Corlette classification, invasion into the portal vessels and the depth of the liver lesion. The portal vein reconstruction was in all cases performed in an “end-to-end”. In all cases we made extended lymphadenectomy.
Results. All complications were classified according to the Dindo-Clavien classification. Postoperative mortality in the main group was 11.5%. The overall 1, 3, 5-year survival in the group 1 was 96%, 68,3%, 57,4%, respectively. 1, 3, 5-year survival rate in the comparison group 2 was 98,4%, 76,7%, 47,3%, respectively.
Conclusions. Aggressive tactics of surgical treatment of perihilar cholangiocarcinoma provides maximum radicality, allows to increase resectability in case of tumor invasion of the portal vein with acceptable mortality and long-term survival.
Measurement on a thin plate of stepped thickness using zero-group velocity effect of an S1 mode Lamb wave induced by a moving laser source
Authors: Li Zheng , Su Dashuai , Sun Xiaofeng 
Published: September 2023

The desired narrowband mode of a Lamb wave can be generated efficiently, as long as the laser’s moving speed matches the mode’s phase velocity, which is a typical characteristic of the moving continuous wave (CW) laser excitation method. In this paper, S1 mode zero group velocity (ZGV) waves can be generated efficiently when the laser’s moving speed matches the phase velocity of the S1 mode at the ZGV point, while the two fundamental Lamb modes, i.e., A0 and S0 waves, can be avoided. Meanwhile, measurements on thin plates of stepped thickness were carried out by using the zero-group velocity effect of the S1 mode. Those simulation results demonstrated that the S1-ZGV resonance can be used to measure the thickness of thin plates by tracking the resonance peak as the sample was scanned, and good accuracy can be achieved, since the measurement was reduced to a simple frequency gauging of sample resonances in the ultrasonic domain, which provides a reliable method to measure a thin plate of varying thickness.
Innovative graphene-dielectric metasurface: harnessing bound states in the continuum for advanced THz-wave modulation and high-sensitivity sensing
Authors: Li Zhexian , Qi Yunping , Zhou Zihao , Bing Luo , Wang Yaqi , Wang Xiangxian 
Published: September 2023

We introduce a metasurface capable of generating multiple bound states in the continuum (BICs). Through the rotation of two LiTaO3 columns, the symmetry protection can be broken, resulting in a quasi-BIC with a high quality factor. The multipolar analysis of each BIC confirms that the dominant pole aligns closely with the electromagnetic field. Additionally, we demonstrate the tunability of the quasi-BIC’s quality factor by modifying the Fermi level of graphene, designing a terahertz (THz)-wave modulator with a remarkable modulation depth more than 90% and a modulation range of 36 meV, 108 meV, 30 meV, 1.2 meV, and 42 meV. Furthermore, the sensing performance of the metasurface is investigated. The sensitivity of peak1 is measured at 0.41 THz/RIU, peak2 at 0.4 THz/RIU, peak3 at 1.049 THz/RIU, peak4 at 0.34 THz/RIU, and peak5 at 1.59 THz/RIU, and the figure of merit of these BICs is calculated as 455.56RIU−1, 62.8RIU−1, 11,655.56RIU−1, 17,000RIU−1, and 7,950RIU−1, respectively. Compared with relevant studies, our metasurface demonstrates excellent performance. The results of these studies have potential applications in sensing, optical communication, and energy harvesting, and open up possibilities for efficient control and manipulation of terahertz waves.