bluuebunny/crossref_metadata_2025_split huggingface dataset:
Research on the Application of Small Caliber Pilot Jacking Method Under Silt Geology
Authors: Wu Qixing , Huang Jieming , Li Qijun , Liu Haoran 
Published: June 2023

AbstractWith the rapid development of urban scale in China, the number of drainage pipes and new construction has also increased rapidly, and pipeline maintenance and new not suitable for excavation construction and silt formation construction due to limited space, and introduce the working principle, construction design, construct construction are facing problems such as environmental protection and narrow construction sites. The use of small-diameter pilot top pulling method can effectively overcome the difficulties of drainage pipeline projects in bustling urban areas that areion process and process of the construction method. Combined with the construction example of a small-caliber pilot top pull method of a drainage pipeline project in Zhongshan City, it shows that the construction technology has the advantages of high precision, space saving, small environmental impact and can be constructed on narrow roads, which can provide reference for similar projects and has greater promotion and application significance.
Lepton flavor physics at μ+μ+ colliders
Authors: Fridell Kåre , Kitano Ryuichiro , Takai Ryoto 
Published: June 2023

Abstract
We discuss sensitivities to lepton flavor violating (and conserving) interactions at future muon colliders, especially at μ+μ+ colliders. Compared with the searches for rare decays of μ and τ, we find that the TeV-scale future colliders have better sensitivities depending on the pattern of hierarchy in the flavor mixings. As an example, we study the case with the type-II seesaw model, where the flavor mixing parameters have direct relation to the neutrino mass matrix. At a μ+μ+ collider, the number of events of the μ+μ+ → μ+τ+ process can be larger than $$ \mathcal{O}(100) $$
O

100

with the center of mass energy $$ \sqrt{s} $$

s

= 2 TeV, and with an integrated luminosity $$ \mathcal{L} $$
L
= 1 ab−1, while satisfying bounds from rare decays of μ and τ. We discuss impacts of the overall mass scale of neutrinos as well as CP violating phases to the number of expected events.
Solar parameters in long-baseline accelerator neutrino oscillations
Authors: Denton Peter B. , Gehrlein Julia 
Published: June 2023

AbstractLong-baseline (LBL) accelerator neutrino oscillation experiments, such as NOvA and T2K in the current generation, and DUNE-LBL and HK-LBL in the coming years, will measure the remaining unknown oscillation parameters with excellent precision. These analyses assume external input on the so-called “solar parameters,”θ12and$$ \Delta {m}_{21}^2 $$∆m212, from solar experiments such as SNO, SK, and Borexino, as well as reactor experiments like KamLAND. Here we investigate their role in long-baseline experiments. We show that, without external input on$$ \Delta {m}_{21}^2 $$∆m212andθ12, the sensitivity to detecting and quantifying CP violation is significantly, but not entirely, reduced. Thus long-baseline accelerator experiments can actually determine$$ \Delta {m}_{21}^2 $$∆m212andθ12, and thus all six oscillation parameters, without input fromanyother oscillation experiment. In particular,$$ \Delta {m}_{21}^2 $$∆m212can be determined; thus DUNE-LBL and HK-LBL can measure both the solar and atmospheric mass splittings in their long-baseline analyses alone. While their sensitivities are not competitive with existing constraints, they are very orthogonal probes of solar parameters and provide a key consistency check of a less probed sector of the three-flavor oscillation picture. Furthermore, we also show that the true values of$$ \Delta {m}_{21}^2 $$∆m212andθ12play an important role in the sensitivity of other oscillation parameters such as the CP violating phaseδ.
Earth mover’s distance as a measure of CP violation
Authors: Davis Adam , Menzo Tony , Youssef Ahmed , Zupan Jure 
Published: June 2023

Abstract
We introduce a new unbinned two sample test statistic sensitive to CP violation utilizing the optimal transport plan associated with the Wasserstein (earth mover’s) distance. The efficacy of the test statistic is shown via two examples of CP asymmetric distributions with varying sample sizes: the Dalitz distributions of B0 → K+π−π0 and of D0 → π+π−π0 decays. The windowed version of the Wasserstein distance test statistic is shown to have comparable sensitivity to CP violation as the commonly used energy test statistic, but also retains information about the localized distributions of CP asymmetry over the Dalitz plot. For large statistic datasets we introduce two modified Wasserstein distance based test statistics — the binned and the sliced Wasserstein distance statistics, which show comparable sensitivity to CP violation, but improved computing time and memory scalings. Finally, general extensions and applications of the introduced statistics are discussed.
Staphylococci planktonic and biofilm environments differentially affect osteoclast formation
Authors: Seebach Elisabeth , Kraus Franziska V. , Elschner Tabea , Kubatzky Katharina F. 
Published: June 2023

Abstract
Introduction
The pathophysiology of chronic implant-related bone infections is characterized by an increase in osteoclast numbers and enhanced bone resorption. Biofilms are a major reason for chronicity of such infections as the biofilm matrix protects bacteria against antibiotics and impairs the function of immune cells. Macrophages are osteoclast precursor cells and therefore linked to inflammation and bone destruction.

Objective and method
Investigations on the impact of biofilms on the ability of macrophages to form osteoclasts are yet missing and we, therefore, analyzed the effect of Staphylococcus aureus (SA) and Staphylococcus epidermidis (SE) planktonic and biofilm environments on osteoclastogenesis using RAW 264.7 cells and conditioned media (CM).

Results
Priming with the osteoclastogenic cytokine RANKL before CM addition enabled the cells to differentiate into osteoclasts. This effect was highest in SE planktonic or SA biofilm CM. Simultaneous stimulation with CM and RANKL, however, suppressed osteoclast formation and resulted in formation of inflammation-associated multinucleated giant cells (MGCs) which was most pronounced in SE planktonic CM.

Conclusion
Our data indicate that the biofilm environment and its high lactate levels are not actively promoting osteoclastogenesis. Hence, the inflammatory immune response against planktonic bacterial factors through Toll-like receptors seems to be the central cause for the pathological osteoclast formation. Therefore, immune stimulation or approaches that aim at biofilm disruption need to consider that this might result in enhanced inflammation-mediated bone destruction.
Mathematical formulation for the numerical solution of the internal ballistics of classical weapons in Lagrangian coordinates
Authors: Kagankiewicz Filip , Magier Mariusz 
Published: June 2023

AbstractToday, most design processes are carried out using specialized tools in the form of advanced computer software, but in the case of designing weapons (especially internal ballistic) it is not generally available or is even classified. On the other hand, there is no analytical system of non-linear differential equations describing the phases of the shot phenomenon in barrel weapons. Therefore, in order to obtain more accurate solutions to the system of equations, it is optimal to use numerical methods. The paper presents a theoretical description of the problem of solving the equations of internal ballistics. Based on this analysis, it was assumed that the solution to the main problem of internal ballistics formulated in Lagrange coordinates gives correct results and enables obtaining more accurate and realistic analytical solutions than using classical solutions. The utilitarian aim was to create a new program to support the design of classic gun tube weapons.
Assessment of return to sport and functional outcomes following distal femoral, double level and high tibial osteotomies for active patients with symptomatic varus malalignment
Authors: An Jae‐Sung , Mabrouk Ahmed , Khakha Raghbir , Kley Kristian , Koga Hideyuki , Jacquet Christophe , Ollivier Matthieu 
Published: June 2023

AbstractPurposeThis study indicated the outcomes of three surgical techniques for the treatment of symptomatic unicompartmental knee osteoarthritis (UKOA) with varus malalignment in younger, active patients: distal femoral osteotomy (DFO), double‐level osteotomy (DLO) and high tibial osteotomy (HTO). The outcomes measured included the return to sport, sport activity and functional scores.MethodsA total of 103 patients (19 DFO, 43 DLO, 41 HTO) were enrolled in the study and were divided into three groups based on their oriented deformity, each undergoing one of the three surgical techniques. All patients underwent pre‐ and post‐operative evaluations including X‐rays, physical exams and functional assessments.ResultsAll three surgical techniques were effective in treating UKOA with constitutional malalignment. The average time to return to sport was similar among the three groups (DFO: 6.4 ± 0.3 [5.8–7] months, DLO: 4.9 ± 0.2 [4.5–5.3] months, HTO: 5.6 ± 0.2 [5.2–6] months). The sport activity and functional scores improved significantly for all three groups, with no significant differences observed among the groups.ConclusionVarious knee osteotomy procedures, DFO, DLO, and HTO, result in high RTS rates and quick RTS times with satisfactory functional scores. Despite pre‐ to post‐operative improvements in sport activities following DFO and DLO, pre‐symptom levels were not reached following all evaluated procedures.Level of evidenceRetrospective case–control study, Level III.
Cross‐cultural adaptation, validity and reliability of the Arabic version of the Forgotten Joint Score for knee arthroplasty
Authors: Albishi Waleed , AbuDujain Nasser M. , Arafah Orfan , Alshaygy Ibrahim S. , Aldosari Zyad A. , Alhuqbani Mohammed N. , Alangari Saad M. 
Published: June 2023

AbstractPurposeTo evaluate the validity and reliability of the Arabic version of this questionnaire in Arabic patients who underwent total knee arthroplasty (TKA).MethodsThe Arabic version of the English FJS (Ar‐FJS) was modified according to cross‐cultural adaptation best practices. The study included 111 patients who underwent TKA 1–5 years ago and completed the Ar‐FJS. The reduced Western Ontario and McMaster Universities Osteoarthritis Index (rWOMAC) and 36‐Item Short Form (SF‐36) were used to assess the construct validity of the study. Fifty‐two individuals took the Ar‐FJS test twice to evaluate the test–retest reliability.ResultsThe reliability of the Ar‐FJS demonstrated a Cronbach's α value of 0.940 and an intraclass correlation coefficient of 0.951. The ceiling effect of the Ar‐FJS was 5.4% (n = 6), whereas the floor effect was 1.8% (n = 2). Additionally, the Ar‐FJS showed correlation coefficients of 0.753 and 0.992 for the rWOMAC and SF‐36, respectively.ConclusionThe Ar‐FJS‐12 demonstrated excellent internal consistency, repeatability, construct validity, and content validity and can be recommended for patients in Arabic‐speaking communities who have undergone knee arthroplasty.
Intraoperative control by Schanz‐screws is inaccurate to achieve the exact amount of correction in de‐rotational osteotomies
Authors: Ferner Felix , Klinder Annett , Woerner Michael , Morris Patrick , Harrer Joerg , Dickschas Joerg , Lutter Christoph 
Published: June 2023

AbstractPurposeThe accuracy of intraoperative control of correction commonly is achieved by K‐wires or Schanz‐screws in combination with goniometer in de‐rotational osteotomies. The purpose of this study is to investigate the accuracy of intraoperative torsional control in de‐rotational femoral and tibial osteotomies. It is hypothesized, that intraoperative control by Schanz‐screws and goniometer in de‐rotational osteotomies around the knee is a safe and well predictable method to control the surgical torsional correction intraoperatively.Methods55 consecutive osteotomies around the knee joint were registered, 28 femoral and 27 tibial. The indication for osteotomy was femoral or tibial torsional deformity with the clinical occurrence of patellofemoral maltracking or PFI. Pre‐ and postoperative torsions were measured according to the method of Waidelich on computed tomography (CT) scan. The scheduled value of torsional correction was defined by the surgeon preoperatively. Intraoperative control of torsional correction was achieved by 5 mm‐Schanz‐screws and goniometer. The measured values of torsional CT scan were compared to the preoperative defined and intended values and deviation was calculated separately for femoral and tibial osteotomies.ResultsThe surgeon’s intraoperative measured mean value of correction in all osteotomies was 15.2° (SD 4.6; range 10–27), whereas the postoperatively measured mean value on CT scan was 15.6 (6.8; 5.0–28.5). Intraoperatively the femoral mean value measured 17.9° (4.9; 10–27) and 12.4° (1.9; 10–15) for the tibia. Postoperatively the mean value for femoral correction was 19.8 (5.5; 9.0–28.5) and 11.3 (5.0; 5.0–26.0) for tibial correction. When considering a deviation of plus or minus 3° to be acceptable femorally 15 osteotomies (53.6%) and tibially 14 osteotomies (51.9%) fell within these limits. Nine femoral cases (32.1.%) were overcorrected, four cases undercorrected (14.3%). Four tibial cases of overcorrection (14.8%) and 9 tibial cases of undercorrection (33.3%) were observed. However, the observed difference between femur and tibia regarding the distribution of cases between the three groups did not reach significance. Moreover, there was no correlation between the extent of correction and the deviation from the intended result.ConclusionThe use of Schanz‐screws and goniometer in de‐rotational osteotomies as an intraoperative control of correction is an inaccurate method. Every surgeon performing derotational osteotomies must consider this and include postoperative torsional measurement in his postoperative algorithm until new tools or devices are available to guarantee a better intraoperative accuracy of torsional correction.Study designObservational study.Level of evidenceIII.
Bleeding risk in female patients undergoing intravesical injection of onabotulinumtoxinA for overactive bladder: a Danish retrospective cohort study
Authors: El Issaoui Meryam , Elissaoui Sophia , Elmelund Marlene , Klarskov Niels 
Published: June 2023

Abstract
Introduction and hypothesis
We aimed to examine the risk of bleeding in female patients undergoing intravesical onabotulinumtoxinA (BTX-A) treatments and provide clinical recommendations for the perioperative management of patients on antithrombotic therapy prior to BTX-A treatments.

Methods
This was a retrospective cohort of Danish female patients, who had their first BTX-A treatment because of an overactive bladder at the Department of Gynecology and Obstetrics, Herlev and Gentofte University Hospital, between January 2015 and December 2020. Data extraction was from an electronic medical journal system. BTX-A, Botox® Allergan was injected in the detrusor at 10–20 sites. Significant bleeding during or after a BTX-A treatment was defined as persistent macroscopic hematuria. Bleeding reporting was based on information obtained from journal notes.

Results
We included 400 female patients, who had a total of 1,059 BTX-A treatments. Median age at first BTX-A treatment was 70 years (IQR 21), and median number of BTX-A treatments was 2 (range 1–11). In total, 27.8% (n=111) received antithrombotic therapy. Within this group, 30.6% and 69.4% were on anticoagulant and antiplatelet therapy. No cases of hematuria were reported in our cohort. We found that no patients stopped their antithrombotic therapy, were bridged, or monitored by International Normalized Ration (INR) levels.

Conclusions
We suggest that BTX-A treatments might be classified as low-risk procedures. Discontinuation of antithrombotic therapy is not required in the perioperative management of this patient group.
Assessing attention and impulsivity in the variable stimulus duration and variable intertrial interval rodent continuous performance test schedules using noradrenaline receptor antagonists in female C57BL/6JRj mice
Authors: Klem L. , Nielsen M. M. , Gestsdóttir S. B. , Frandsen S. L. , Prichardt S. , Andreasen J. T. 
Published: June 2023

Abstract
Rationale
Noradrenergic dysfunction is associated with disorders of impulsivity and inattention. The rodent continuous performance test (rCPT) quantifies changes in attention and impulsivity.

Objective
To use NA receptor antagonists to examine the roles of NA on attention and impulsivity behaviours measured in the rCPT variable stimulus duration (vSD) and the variable intertrial interval (vITI) schedules.

Methods
Two cohorts of 36 female C57BL/6JRj mice were examined separately in the rCPT vSD and vITI schedules. Both cohorts received antagonists of the following adrenoceptors: α1 (doxazosin, DOX: 1.0, 3.0, 10.0 mg/kg), α2 (yohimbine, YOH: 0.1, 0.3, 1.0 mg/kg), and β1/2 (propranolol, PRO: 1.0, 3.0, 10.0 mg/kg) in consecutive balanced Latin square designs with flanking reference measurements. The antagonists were subsequently examined for effects on locomotor activity.

Results
DOX showed similar effects in both schedules, improving discriminability and accuracy, and reducing responding and impulsivity, and DOX also reduced locomotor activity. YOH showed prominent effects in the vSD schedule to increase responding and impulsivity, while impairing discriminability and accuracy. YOH did not affect locomotor activity. PRO increased responding and impulsivity, decreased accuracy, but did not affect discriminability or locomotor activity.

Conclusion
Antagonism of α2 or β1/2 adrenoceptors caused similar increases in responding and impulsivity and worsened attentional performance, while α1 adrenoceptor antagonism showed the opposite effects. Our results suggest that endogenous NA exerts bidirectional control of most behaviours in the rCPT. The parallel vSD and vITI studies showed a substantial overlap in effects, but also some differences that indicate differing sensitivity towards noradrenergic manipulations.
Associative Submanifolds in Joyce’s Generalised Kummer Constructions
Authors: Dwivedi Shubham , Platt Daniel , Walpuski Thomas 
Published: June 2023

AbstractThis article constructs examples of associative submanifolds in$$G_2$$G2–manifolds obtained by resolving$$G_2$$G2–orbifolds using Joyce’s generalised Kummer construction. As the$$G_2$$G2–manifolds approach the$$G_2$$G2–orbifolds, the volume of the associative submanifolds tends to zero. This partially verifies a prediction due to Halverson and Morrison.
No impact of attenuation and scatter correction on the interpretation of dopamine transporter SPECT in patients with clinically uncertain parkinsonian syndrome
Authors: Schiebler Tassilo , Apostolova Ivayla , Mathies Franziska Lara , Lange Catharina , Klutmann Susanne , Buchert Ralph 
Published: June 2023

Abstract
Purpose
The benefit from attenuation and scatter correction (ASC) of dopamine transporter (DAT)-SPECT for the detection of nigrostriatal degeneration in clinical routine is still a matter of debate. The current study evaluated the impact of ASC on visual interpretation and semi-quantitative analysis of DAT-SPECT in a large patient sample.

Methods
One thousand seven hundred forty consecutive DAT-SPECT with 123I-FP-CIT from clinical routine were included retrospectively. SPECT images were reconstructed iteratively without and with ASC. Attenuation correction was based on uniform attenuation maps, scatter correction on simulation. All SPECT images were categorized with respect to the presence versus the absence of Parkinson-typical reduction of striatal 123I-FP-CIT uptake by three independent readers. Image reading was performed twice to assess intra-reader variability. The specific 123I-FP-CIT binding ratio (SBR) was used for automatic categorization, separately with and without ASC.

Results
The mean proportion of cases with discrepant categorization by the same reader between the two reading sessions was practically the same without and with ASC, about 2.2%. The proportion of DAT-SPECT with discrepant categorization without versus with ASC by the same reader was 1.66% ± 0.50% (1.09–1.95%), not exceeding the benchmark of 2.2% from intra-reader variability. This also applied to automatic categorization of the DAT-SPECT images based on the putamen SBR (1.78% discrepant cases between without versus with ASC).

Conclusion
Given the large sample size, the current findings provide strong evidence against a relevant impact of ASC with uniform attenuation and simulation-based scatter correction on the clinical utility of DAT-SPECT to detect nigrostriatal degeneration in patients with clinically uncertain parkinsonian syndrome.
Epidemiological features of acute medial meniscus posterior root tears
Authors: Kamatsuki Yusuke , Furumatsu Takayuki , Hiranaka Takaaki , Okazaki Yuki , Kintaka Keisuke , Kodama Yuya , Miyazawa Shinichi , Ozaki Toshifumi 
Published: June 2023

Abstract
Purpose
Untreated or overlooked medial meniscus posterior root tears (MMPRTs) induce sequential knee joint degradation. We evaluated epidemiological features of acute MMPRT for its early detection and accurate diagnosis.

Methods
Among 330 MMPRT patients from 2018 to 2020, those who underwent arthroscopic pullout repairs were enrolled. Patients who underwent non-operative treatment or knee arthroplasty, those with a cruciate ligament-deficient knee or advanced osteoarthritis of the knee, and those with insufficient data were excluded. Finally, we retrospectively evaluated data from 234 MMPRTs (female: 79.9%, complete tears: 92.7%, mean age: 65 years). Welch’s t-test and Chi-squared test were used for pairwise comparisons. Spearman’s rank correlation analysis was performed between age at surgery and body mass index (BMI). Multivariable logistic regression analysis with stepwise backward elimination was applied to the values as risk factors for painful popping events.

Results
In both sexes, there were significant differences in height, weight, and BMI. In all patients, there was a significant negative correlation between BMI and age (ρ =  − 0.36, p < 0.001). The BMI cutoff value of 27.7 kg/m2 had a 79.2% sensitivity and a 76.9% specificity for detecting MMPRT patients aged < 50 years. A painful popping event was confirmed in 187 knees (79.9%), and the frequency was significantly reduced in partial tears as compared to complete tears (odds ratio: 0.080, p < 0.001).

Conclusion
Higher BMI was associated with a significantly younger age of MMPRT onset. Partial MMPRTs had a low frequency of painful popping events (43.8%).