bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kidney invasion occurred 2 years following liver transplantation for hepatic alveolar echinococcosis: a case report.
Authors: Hu Qirui , Chen Simin , Fan Yichen , Lu Qian , Deng Manjun , Fan Haining 
Published: September 2023

Abstract
The organ most commonly invaded by echinococcosis is the liver; the lungs, brain, kidneys, heart, and spleen are rarely invaded, and echinococcosis with multiorgan involvement is even rarer. We report the course and disease progression of a rare case of renal echinococcosis that occurred after liver transplantation and partial lung resection in a patient diagnosed with hepatic multilocular echinococcosis with pulmonary metastases, as a reference and warning for future clinical management of similar cases.
Magnitude and determinants of food insecurity among pregnant women in Nigeria: evidence from a nationwide cross-sectional survey
Authors: Ogbuabor Daniel Chukwuemeka 
Published: September 2023

Abstract
Background
Food security is crucial to improve maternal nutrition during pregnancy. However, evidence of the magnitude and social determinants of food insecurity among pregnant women is scarce in Nigeria. Therefore, this study used nationally representative data to assess the prevalence and determinants of food insecurity among pregnant women in Nigeria.
Methods
The study setting was Nigeria. The study is a secondary analysis of data from the Nigeria Demographic and Health Survey 2018 using a cross-sectional household survey design. We adjusted the data for sampling weight, stratification, and cluster sampling design. The dependent variable was food security status: food security (dietary diversity) and food insecurity (no dietary diversity). The independent variables included women's socio-demographic and household characteristics. We cross-tabulated food security status and pregnant women's characteristics to measure the association using the Chi-square statistics. We included all significant variables from the bivariate analysis in a complex sample logistic regression model to determine the adjusted effect of each independent variable on food insecurity. We set the statistical significance for all inferential analyses at p <0.05.
Results
The prevalence of food insecurity among pregnant women in Nigeria is 45%. Residing in the North-East (AOR:1.70, 95%CI:1.26-2.29, p<0.001), Southeast (AOR: 1.47, 95%CI:1.04-2.07, p=0.028) regions, having no education (AOR:1.86, 95%CI:1.28-2.70, p=0.001), primary education (AOR:1.86, 95%CI:1.28-2.69, p=0.001), married/living with a partner (AOR:3.33, 95%CI:1.28-8.67, p=0.014), widowed/divorced/separated (AOR:3.83,95%CI:1.68-8.73, p=0.001), non-exposure to television (AOR:1.55, 95%CI:1.26-1.92, p<0.001), healthcare access barrier (AOR:1.69, 95%CI:1.43-1.99, p<0.001) increased pregnant women's likelihood of being food-insecure.
Conclusions
The proportion of food-insecure pregnant women needs to improve in Nigeria. The government and its partners must address the cost of healthy diets, abate conflicts, and strengthen the implementation of food and nutrition policies. It is imperative to incorporate the social determinants of food insecurity identified in this study into policies and plans to improve food security among pregnant women in Nigeria.
A comparison of the usage of an open-source automated insulin delivery system and the MiniMed™ 780G system in children and adolescents with type 1 diabetes in real-world settings: the AWeSoMe Study Group
Authors: Landau Zohar , Lebenthal Yael , Mazor-Aronovitch Kineret , Brener Avivit , Levek Noah , Jacobi-Polishook Talia , Ari Tal Ben , Abiri Shirly , Haim Alon , Nir Judith , Rachmiel Marianna , Pinhas-Hamiel Orit 
Published: September 2023

Abstract
Purpose:
In recent years there has been a noticeable increase in the use of advanced hybrid closed-loop systems (AHCLs) for managing type 1 diabetes (T1D) among youth. However, there is a lack of comparison between the open-source automated insulin delivery (AID) system and the MiniMed™ 780G system (780G).
Methods:
In this multi-center study, we retrospectively compared selected glycemic ranges of 26individuals who used open-source AID and 20 individuals who used 780G (age 11.3 years [IQR 9.3, 12.9] and 13.4 years [IQR10.9, 16.5], respectively, p = 0.069) from system initiation to the most recent visit.
Results:
At baseline, the median HbA1c was significantly lower and the TBR< 54mg/dL was significantly higher in the open-source AID group compared to the 780G group (6.8% [IQR 6.4, 7.1] vs. 7.4% [IQR 6.9, 8.6], p = 0.006 and (1.0% [IQR 0.5, 2.8] vs. 0.0 [0.0, 1.0], p = 0.014), respectively; the median time in range (TIR70-180mg/dL) was similar (p = 0.068). After a median duration of 10.9 months on AHCLs the reduction of HbA1c was similar (~ 0.3%). The time spent in the hypoglycemic ranges was longer among users of the open-source AID compared to 780G (TBR54-70mg/dL 4.2% [IQR 2.6, 7.3] vs. 2.0 [1.0, 4.0], p = 0.005) and TBR< 54mg/dL 1.1% [IQR 0.4, 2.3] vs. 0.0 [0.0, 1.0], p = 0.001).
Conclusions:
Both AHCLs similarly improved HbA1c and TIR70-180mg/dL. The open-source AID youth had better glycemic control but spent longer time in the hypoglycemic range. These findings must be considered when choosing the use of AHCL technologies.
A four-year assessment of the characteristics of Rwandan FDA drug recalls
Authors: Marcel Bahizi , Eric Nyirimigabo , Lazare Ntirenganya , Martine Umuhoza Ishimwe , Vedaste Habyalimana , Gerard Bikorimana , Joyeuse Ukwishaka 
Published: September 2023

Abstract
Background
A drug recall is an act of removing products from the market and/or returning them to the manufacturer for disposal or correction when they violated safety law. The action can be initiated by the manufacturing company or by the order of a regulatory body. This study aims to assess the characteristics of Rwandan FDA drug recall and determine the association between classes of recall and recall characteristics.
Methodology
This was a retrospective descriptive cross-sectional study. Data about recalled drugs were collected from the official website of the Rwandan FDA in the section assigned to “Safety alerts”. The search included the data reported between February 2019 and February 2023 covering a four-year period. Data cleaning was conducted in Microsoft Excel to address missing data and inconsistencies, followed by importation into STATA/SE software version 17.0 for further cleaning and subsequent analysis. Descriptive statistics were computed for independent variables, and categorical variables were described in terms of counts and relative frequencies. Bivariate analyses used Pearson’s chi-square test to illustrate associations between categorical independent variables and the classes of recalls. A p value of < 0.05 was considered statistically significant.
Results
The study revealed that a large proportion of recalled products belonged to Class I of the WHO’s ACT classification, with antibiotics constituting 28.3% of the recalled products. Class I recalls accounted for 33.0% of all recalls, with contamination emerging as a leading cause, responsible for 26.4% of the recalled products and 89.3% of class I recalls. India was the leading manufacturing country for the recalled products (29.2%), followed by France (17.9%), China (17.0%), Kenya (13.2%), and Russia (6.6%). The study also found a significant association between the class of recall and several recall characteristics, including the year of recall, drug category, safety issues, reporter, and manufacturing countries.
Conclusion
This study provides a comprehensive overview of the characteristics of drug recalls in Rwanda. The insights gained contribute to a nuanced understanding of recall dynamics and pave the way for evidence-based strategies to enhance drug quality, safety, efficacy, regulatory compliance and patient welfare.
Young women’s perspectives on a user-friendly self-sampling intervention to improve the diagnosis of sexually transmitted infections in underserved communities in KwaZulu-Natal South Africa
Authors: Jaya Ziningi Nobuhle , Mapanga Witness , Mashamba-Thompson Tivani Phosa 
Published: September 2023

Abstract
Introduction
Young women are disproportionately affected by sexually transmitted infections (STIs), especially in the KwaZulu-Natal province of South Africa. As such they should have easy access to STI healthcare services. The main objective of this study was to collaborate with young women, using a nominal group technique (NGT), to identify barriers to existing STI healthcare services to ultimately identify strategies to inform attributes for a discrete choice experiment (DCE) towards developing a user-friendly self-sampling intervention for STI diagnosis in young women.
Methods
Eight young women, aged 18–24 years, were purposively selected from primary healthcare clinics in underserved communities. A NGT was conducted comprising the following steps: silent generation where individuals considered and recorded their responses to a question; round-robin sharing, recording and discussion of individual responses; followed by ranking of contributions.
Results
The following barriers to accessing STI healthcare services were identified: the clinics were too far from home; young women feared judgement by clinic staff; young women feared being told to inform their partners; clinic hours clashed with school hours and other personal commitments; and young women did not know enough about the signs and symptoms of STIs. The following strategies to improve access to STI healthcare services were suggested: campaigns to promote self-sampling; self-sampling kits should be available free of charge; online system to assess symptoms and register to receive self-sampling kits via delivery or collection to accommodate people with disabilities.
Conclusion
The strategies identified informed the attributes for the DCE which is aimed towards the development of a user-friendly self-sampling interventions for STI diagnosis in young women in KwaZulu-Natal.
LC-MS/MS-QTOF dataset of chlorophyll derivatives and chemical compounds detected in Green Honey (GH) and Tualang Honey (TH) from Malaysia
Authors: ullah Saeed , Huyop Fahrul , Huda Nurul , Wahab Roswanira Ab. , Lani Mohd Nizam , Hamid Azzmer Azzar Abdul , Nasir Mohd Hamzah Mohd , Mohamad Mohd Azrul Naim , Ahmad Hajar Fauzan , Antara Nyoman Semadi , Gunam Ida Bagus Wayan 
Published: September 2023

Abstract
Objective Honey has been valued for its therapeutic properties since ancient times. This study focuses on the unique characteristics and bioactive compounds of Tualang Honey (TH) and a newly discovered Green Honey (GH) from Banggi Island's forest subsurface region. The uniqueness of the green honey product has led to a high market value, distinguished by its green color, attributed to a significant amount of chlorophyll. However, GH's diverse range of chlorophyll and other bioactive compounds remains uncertain. This study aims to analyze and compare the chlorophyll components and other bioactive compounds in TH and GH using targeted and untargeted approaches. The LC MS/MS QTOF system with a HyPURITY C18 column, and a gradient mobile phase of methanol and acetone, operated in negative-positive mode, were used to separate the chlorophylls and chemical compounds in both honey samples within 40 minutes with a flow rate of 1 ml/min. Detection was achieved at A660nm, and identification was based on retention time, mass spectra, and mass-to-charge ratio.
Results The LC-MS/MS-based targeted analysis revolved 16 different chlorophylls and their derivatives in GH, namely chlorophyll a, chlorophyll b, chlorophyll c, chlorophyll d, pheophytin a, pheophytin b, hydroxypheophytin a, hydroxypheophytin b, hydroxychlorophyll a, chlorophyllide a, chlorophyllide b, phyropheophytin a, bacteriochlorophyll a, bacteriochlorophyll b, phytol and phytanic acids whereas none were found in TH. On the other hand, the untargeted analysis revealed 32 known and 21 unknown chemical compounds in GH and 15 known and 20 unknown compounds in TH, respectively.
Data Description This dataset represents the compilation of chemical compounds and chlorophyll components detected in GH, for both untargeted and targeted analytical approaches, respectively. The untargeted analysis was performed to identify a wide range of chemical compounds present in both GH and TH. The dataset encompasses compound names, mass-to-charge values, species, retention times, and various METLIN database search results, providing comprehensive insights into the composition of these honeys.
Robust optimization for prostate radiotherapy: Assessment of delivered dose by incorporating intrafraction prostate position deviations
Authors: Arumugam Sankar , Sidhom Mark 
Published: September 2023

Abstract
Aim
To assess the robustness of the dose delivered to the clinical target volume (CTV) using planning target volume (PTV) based and robust optimization planning approaches in localized prostate cancer radiotherapy.
Methods
Retrospective data of twenty prostate cancer patients, including radiotherapy and real-time prostate position, were analyzed. Two sets of volumetric modulated arc therapy plans were generated per patient: PTV-based and robust optimization. PTV-based planning used 7mm CTV-PTV margin, while robust planning considered same-magnitude position deviations. Differences in CTV D99, PTV D95, bladder and rectum V40, and V60 values were evaluated. The target position, determined by in-house position monitoring system, was incorporated for dose assessment with and without position deviation correction.
Results
In the robust optimization approach, compared to PTV-based planning, the mean (SD) V40 and V60 values of the bladder were reduced by 5.2% (4.1%) and 5.1% (1.9%), respectively. Similarly, for the rectum, the reductions were 0.8% (0.5%) and 0.6% (0.6%). In corrected treatment scenarios, both planning approaches resulted in a mean (SD) CTV D99 difference of 0.1 Gy (0.1 Gy). In the not corrected scenario, PTV-based planning reduced CTV D99 by 0.1 Gy (0.5 Gy), while robust planning reduced it by 0.2 Gy (0.6 Gy). There was no statistically significant difference observed in the planned and delivered rectum and bladder dose for both corrected and not corrected scenarios.
Conclusion
Robust optimization resulted in lower V40 and V60 values for the bladder compared to PTV-based planning. However, no difference in CTV dose accuracy was found between the two approaches.
Effects of Exogenous Melatonin on wheat quality under drought stress and rehydration
Authors: Fu Yuanyuan , Li Penghui , Liang Yueping , Si Zhunyun , Ma Shoutian , Gao Yang 
Published: September 2023

Abstract
Melatonin (MT) regulates and enhances crop tolerance to drought stress. However, the effect of melatonin spraying on grain quality under drought-rehydration treatment is evaluated insufficiently currently. Here, the present study is conducted by spraying 100mM MT before wheat grain-filling and then drought-rehydration treatment is carried out. Rewatering after drought stress increased appreciably wet gluten content, sedimentation index, total protein content, and glutein content of wheat grains and decreased prolainm content, albumin content, and globulin content. And MT application effectively alleviated grain quality damage, reducing wet gluten content and glutein content. Besides, MT compensated for the oxidative damage and the membrane lipid peroxidation damage caused by drought-rehydration treatment. In addition, two drought stresses reduced significantly photosynthetic parameters. And MT effectively improved the photosynthetic efficiency. These results indicated that MT was feasible to enhance wheat resistance and ameliorate grain quality during drought and rehydration.
Occurrence of ochratoxin A in breast milk and urine samples of nursing mothers in Bangladesh
Authors: Trisha Aporajita Das , Hafsa Jaasia Momtahena , Hasan Akibul , Habib Ahsan , Tuba Humaira Rashid , Degen Gisela H. , Ali Nurshad 
Published: September 2023

Abstract
The mycotoxin ochratoxin A (OTA) is a potent nephrotoxin with carcinogenic properties and thus of concern as food contaminant. Since food contaminant data are scarce in Bangladesh, we applied human biomonitoring to gain more insights into OTA exposure in the country’s population. OTA concentrations in human milk and urine samples of nursing mothers were determined with the aim to assess also exposure to this mycotoxin in breastfed infants. Breastfeeding mothers (n=74) from three districts of Bangladesh (Sylhet, Cumilla, and Mymensingh region) participated in this study. They provided demographic data, along with breast milk and urine samples. OTA levels were measured by a competitive enzyme-linked immunosorbent assay (ELISA) with a detection limit of 60 ng/L for milk and 30 ng/L for urine.
OTA was detected in 62.2% of all breast milk samples (mean 102.1±43.5 ng/L, range LOD–243.3 ng/L) and in 51.4% of all urine samples (mean 72.1±79.5 ng/L, range LOD–519.3 ng/L). Differences observed between regions (Sylhet, Cumilla, Mymensingh) for mean breast milk or for urinary OTA levels were relatively small. No significant correlation was observed between OTA levels in breast milk and food consumption patterns among the nursing mothers. Regarding infant exposure, the estimated average daily intake of OTA for all was 15.0 ng/kg bw/day (range 2.8–45 ng/kg bw/day). In 34.5 % of these infants, their estimated daily OTA intake exceeded a preliminary TDI value set by EFSA (17 ng/kg bw/day). The mean OTA intake was slightly higher (16.2±7.8 ng/kg bw/day) in 1-2 months babies than in older infants (<2 to 12 months) although the difference was not significant. Presence of OTA in most milk and urine samples of nursing mothers documents their widespread dietary mycotoxin exposure. Although based on a relatively small number of participants, the present analysis indicates non-negligible exposure of some nursed infants in Bangladesh. Therefore, further biomonitoring studies and investigations on major sources of OTA in food commodities are encouraged.
Stability and spin solitonic dynamics of the HFSC model: effects of neighboring interactions and crystal field anisotropy parameters
Authors: Islam Zahidul , Sheikh Md. Abu Naim , Roshid Harun-Or , Hossain M. A. , Taher M.A. , Abdeljabbar Alrazi 
Published: September 2023

Abstract
This research investigates spin dynamic solitonic wave solutions in the (2 + 1)-dimensional Heisenberg Ferromagnetic Spin Chains model. The unified and simple equation schemes are used to integrate the model. Through the technique, various properties of wave nature, such as Dark bell envelope soliton, Bright bell envelope soliton, periodic wave envelope, Kink shape envelope soliton, periodic wave envelope soliton, oscillating wave, harmonically oscillating wave, oscillating wave with increasing and decreasing amplitude waves, sudden increasing of amplitude and sudden decrease to a particular amplitude wave oscillations, are achieved from the solutions. The effects of changing neighboring interaction and uniaxial crystal field anisotropy parameters on the obtained soliton and its amplitudes are explored. The changing values of neighboring interaction parameters are exhibited as an increase in wave height with increasing parametric values, but increasing the values of the uniaxial crystal field anisotropy parameter causes a reduction in wave height. In the mean time, we see that the real part of the same solution exhibits periodic oscillation while the effects of the parameters have the same increasing and decreasing effects. Analysis of odulation stability found due to small change as perturbation solution of the model. All shapes are illustrated in 3D and 2D plots.
Synthesis of Metallic and Metal Oxides Nanoparticles by using Poly(4- vinylpyridine) (P4VP), Poly(2-vinylpyridine) (P2VP) Homopolymers and Polyphosphazene-b-P2VP Block Copolymers as Solid Templates
Authors: Cortés María de los Ángeles , Díaz Carlos , Valenzuela María Luisa , Campa Raquel , Soto Alejandro Presa 
Published: September 2023

Abstract
Starting from poly(4-vinylpyridine) [(P4VP)n; Mw = 6000 (1a); 160000 (1b)]; poly(2-vinylpyridine) Mw = 37500 (1c) and [N=P(O2CH2CF3)]m-b-P2VP20 block copolymers [m = 20 (2a); 60 (2b) and 100 (2c)], series of metal- containing homopolymers {[P4VP(PtCl2)x]6000 (1a-Pt), [P4VP(PtCl2)x]160000 (1b-Pt), [P2VP(PtCl2)x]37500 (1c-Pt), [P4VP(ZnCl2)x]6000 (1a-Zn), [P4VP(ZnCl2)n]160000 (1b-Zn), [P2VP(ZnCl2)n]37500 (1c-Zn), [P4VP(Eu(NO3)3]6000 (1a-Eu), and [P4VP(Eu(NO3)3]160000 (1b-Eu) P2VP[(Eu(NO3)3]37500 (1c-Eu) and block copolymers {[N=P(O2CH2CF3)]20-b-[P2VP(Eu(NO3)3)x]20 (2a-Eu), [N=P(O2CH2CF3)]60-b-[P2VP(Eu(NO3)3)x]20 (2b-Eu) and [N=P(O2CH2CF3)]100-b-[P2VP(Eu(NO3)3)x]20 (2c-Eu)} have been successfully prepared by using a direct a straight forward solution metodólogy. Solid-state pyrolysis of the as prepared metal containing polymeric precursors lead to the formation of a variety of different metallic and metal oxide nanoparticles (Pt, ZnO, Eu2O3 and EuPO4) depending on the composition and nature of the polymeric template precursor. Thus, whereas Eu2O3 nanostructures were obtained from europium-containing homopolymers (1a-Eu, 1b-Eu and 1c-Eu), EuPO4 nanostructures were achieved when phosphorus-containing block copolymer precursors (2a-Eu, 2b-Eu and 2c-Eu) were employed. Importantly, and although both Eu2O3 and EuPO4 nanostructures exhibit a strong luminescence emission, this is strongly influenced by the nature and composition of the macromolecular metal-containing polymer template. Thus, when P2VP europium-containing homopolymers (1a-Eu, 1b-Eu and 1c-Eu) were employed, the highest emission intensity corresponds to the lowest molecular weight homopolymer template (1a-Eu), whereas opposite behavior was observed when block copolymer precursors (2a-Eu, 2b-Eu and 2c-Eu) were used (highest emission intensity corresponds to 2c-Eu). The intensity ratio of the emission transitions 5D0→ 7F2/5D0→ 7F1 suggest a different symmetry around the Eu3+ ions depending on the nature of the polymeric precursor, which also influences the sizes of the as prepared Pt, ZnO, Eu2O3 and EuPO4 nanostructures.
Alterations in the Haemotological and Biochemical Responses of Exposed to Allium sativum Extract Against Cadmium Oxide in Male Swiss Albino Mice
Authors: Feridun Gulbin , Kargin Dicle , Cogun Hikmet Yeter , Kargin Ferit , Feridun Beran 
Published: September 2023

Abstract
In this study following exposures of 1.5 mg/kg/day Cadmium oxide (CdO) and 1.5 mg/kg/day CdO + 300 mg/kg Allium sativum extract (mixture) were individually administered to mature in Male Swiss Albino Mice via oral gavage for 96 hours and then haemotological and biochemical responses were investigated. Hematological indices (hemoglobin (Hb), hematocrit (Hct), red blood cells (RBC), white blood cells (WBC), platelets (PLT); serum metabolites (total cholesterol, cortisol, triglyceride, glucose, total protein, bilirubin), ions (Na, K, Cl, Mg, Ca and fosfat), and enzymes; (alanine transaminase (ALT); aspartate transaminase (AST), alkaline phosphatase, (ALP) and laktat dehidrogenaz (LDH), lipase (LP)) levels were measured. CdO and mixture decreased hematological indices (except PLT); ALP and ChE, serum metabolits (except glucose and bilirubin); ions (except K, Na) while increased PLT, ALT, AST, LDH, LP, glucose, bilirubin and K ion. These increases/decreases in all hematological and biochemical parameters were generally higher in mice treated with the exposed CdO compared to the mixture of CdO and Allium sativum extract group. The study demonstrated that ameliorative effect of Allium sativum extract on metal toxicity evaluating enzyme systems, ion regulation, hematological values and metabolism as lipid, protein, and energy.