bluuebunny/crossref_metadata_2025_split huggingface dataset:
Antibacterial and Mechanical Properties of Pit and Fissure Sealants Containing Zinc Oxide and Calcium Fluoride Nanoparticles
Authors: Swetha Dara Lakshmi , Vinay C. , Uloopi K. S. , RojaRamya Kakarla Sri , Chandrasekhar Rayala 
Published: February 2023

Context:Pit and fissure sealants (PFSs) are the most effective preventive materials in dentistry. Secondary caries around the sealed pits and fissures at the material–tooth interface and the wear of the material remains the common problems. To address these problems, efforts have been made by incorporating zinc oxide (ZnO) and calcium fluoride (CaF2) nanoparticles (NPs) into the sealants to develop caries-inhibiting and stress-bearing sealants.Aim:Evaluation of antibacterial and mechanical properties of PFS containing ZnO and CaF2NPs.Settings and Design:This was anin vitrostudy.Materials and Methods:A total of 196 fissure sealant samples were divided into six test groups and a control group. The test group samples were prepared by incorporating two concentrations (0.5 wt% and 1 wt%) of ZnO and CaF2NPs into the sealants. The antibacterial activity was evaluated by direct contact test; compressive and flexural strengths were evaluated by a universal testing machine.Statistical Analysis Used:Statistical analysis was done by one-way ANOVA andpost hocTukey test.Results:Sealants containing 1 wt% ZnO and CaF2NPs and their mixture exhibited significantly higher antibacterial activity againstStreptococcus mutansandLactobacillus acidophiluswhen compared to control group (P< 0.001). Samples with ZnO NPs exhibited similar mechanical properties as conventional sealant (control group); however, the samples with CaF2NPs showed inferior mechanical properties (P< 0.05).Conclusion:The observations of the study infer that sealants containing 1 wt% ZnO and CaF2NPs and their mixture exhibited superior antibacterial activity. The mechanical properties of samples containing ZnO and mixture of ZnO and CaF2particles remained comparable to the conventional sealants.
Root Anatomy of Mandibular Second Premolars in French Subpopulation
Authors: Kharouf Naji , Haikel Youssef , Mancino Davide 
Published: February 2023

Aims:
The purpose of this in vivo study is to illustrate endodontic anatomical variants in French subpopulations of human mandibular second premolars to show if the literature matches our findings.

Setting and Design:
This was an observational retrospective study.

Subjects and Methods:
This study was performed from September 2016 to September 2017. It was conducted on 56 successive cases of root canal therapies on the mandibular second premolars. All procedures were done in conformity with current state-of-the-art practices in endodontics. These included rigorous clinical and radiographic preaccess analysis, appropriate tooth restoration to insure watertight rubber dam installation, surgical microscopic manipulations for precision, systematic use of ultrasonic endodontic tips to manage cavity access preparation, and step-down technique to shape the root canal systems.

Statistical Analysis Used:
Fifty-six mandibular second premolars were treated: 76.8% had one canal, and 23.2% had two or more canals.

Conclusions:
The incidence of two or more canals on mandibular second premolars could be underestimated as our results show. To prevent any missing canals, clinicians must have a perfect knowledge of anatomic variants of the root canal system. Moreover, the systematic use of a surgical microscope, ultrasonic endodontic tips, and a modern step-down technique should facilitate and standardize access cavity preparation, canal localization, and instrumentation.
High-Mobility Group Box 1 Expression in Mandibular Bone Cells of Experimental Periodontitis
Authors: Da’at Arina Yuliana Mahdiyah , Rubianto Mohamad , Ferdiansyah F. , Sudiana I. Ketut , Rahayu Retno Pudji , Notobroto Hari Basuki 
Published: February 2023

Background:
High-mobility group box 1 (HMGB1) was suggested to be associated with the pathogenesis of chronic periodontitis which characterized by alveolar bone loss. HMGB1 was defined as a bone-active cytokine, but the rule of HMGB1 in bone loss of chronic periodontitis is still understood.

Aim:
The aim of this study is to investigate the expression of HMGB1 on osteoblasts and osteoclasts in the mandible of chronic periodontitis.

Methods:
This experimental study was conducted to rats injected by Porphyromonas gingivalis into the buccal and lingual subgingival area at a concentration of 2 × 109 CFU/mL three times a week with 2-day apart for 2, 3, 4, and 6 weeks as chronic periodontitis group and injected by normal saline as control group. Analysis of variance was used to examine the differences between groups followed by least significant difference post hoc test with the level of significance was <0.05.

Results:
The HMGB1 expression was found in both osteoclasts and osteoblasts of mandibular bone by immunohistochemistry analysis. There was a difference of HMGB1 expression on osteoblasts and osteoclasts of chronic periodontitis. HMGB1 expression was found increased significantly in mandibular osteoblasts of chronic periodontitis, whereas the HMGB1 expression in mandibular osteoclast is higher in 2 and 3 weeks, but it was lower in 4 and 6 weeks.

Conclusions:
This study indicated a potential role for HMGB1 in bone loss of chronic periodontitis. HMGB1 on mandibular osteoclasts and osteoblasts may play different rules in the onset and progression of chronic periodontitis.
Evaluation of Efficacy of Curcumin along with Lycopene and Piperine in the Management of Oral Submucous Fibrosis
Authors: Mahato Basudev , Prodhan Chandraday , Mandal Samir , Dutta Avirup , Kumar Parna , Deb Tushar , Jha Tarun , Chaudhuri Keya 
Published: February 2023

Context:
Oral submucous fibrosis (OSMF) is a high-risk premalignant condition of the oral cavity and oropharynx. Complete regression of the disease is still not possible with available treatment modalities.

Aims:
The aim of the study was to evaluate the efficacy of curcumin, lycopene, and piperine as a combination in the management of OSMF.

Settings and Design:
Efficacy was evaluated on the basis of improvement in clinical parameters (i.e., visual Analog Scale [VAS]) score for burning sensation, mouth opening (MO), mucosal flexibility (MF), and tongue protrusion [TP]).

Materials and Methods:
Forty patients clinically and histopathologically diagnosed with OSMF were included in the study; patients were administered with the above-stated drug combination, and clinical parameters were evaluated at regular intervals to compare the pre- and post-treatment measurements.

Statistical Analysis Used:
Paired t-test was done to evaluate significance of the results.

Results:
Highly significant improvement was observed for posttreatment reduction in VAS score for burning sensation and increase in MO (P < 0.001). Significant improvement was also observed in the increase of MF and TP. Posttreatment histopathological evaluation also revealed reepithelialization, indicated by significant increase in the epithelial thickness as found through quantitative image analysis. Immunohistochemical studies with Col1A1 showed decrease in collagen deposition.

Conclusions:
Taken together, the present study proposes the usage of combination drug therapy for the management of OSMF as an effective and affordable way.
Robotic Sacrocolpopexy with Autologous Fascia Lata
Authors: Damiani Gianluca Raffaello , Villa Mario , Falcicchio Giovanni , Cesana Cristina , Malvasi Antonio , Picardi Nico , Vergottini Giovanni , Piero Poli , Dellino Miriam , Loizzi Vera , Vimercati Antonella , Cicinelli Ettore , Pellegrino Antonio 
Published: February 2023

Objectives:
Apical prolapse involves the upper vagina or vaginal vault after hysterectomy. Treatment is indicated for symptomatic women, and surgical approach is considered for women who failed or refused conservative therapy. We performed 10 pickups of autologous fascia, used for robotic sacrocolpopexy (RSCP).

Materials and Methods:
We included patients between 60 and 80 years old who showed a Pelvic Organ Prolapse Quantification (POP-q) over the second stage and with symptoms related to prolapse.

Results:
All of them underwent autologous fascia lata (AFL) pickup from the right leg and after to RSCP. One patient underwent also posterior colporrhaphy. The mean intraoperative time was 199.2 min (183–230 min). No intra-operatory complications were reported. POP-q assessment during follow-up showed improvements: C point gained on average 7.6 points (5–8) and mean values went from −0.6 to − 8.2 cm (−7 to −9 cm). The three women who had anterior compartment defects shows good anatomical reconstitution with a mean Aa and Ba value of − 2.83 cm (−2.5 to −3 cm) and gained 4 points (average gain: 3.5–4.5 cm). Total vaginal lenght (TVL).

Conclusion:
According to these data, in our experience, AFL employment showed a good anatomical result from the first to last follow-up.
Evolution of anaesthesia technique for endolaryngeal surgery through and post-COVID-19 pandemic: An experience from a tertiary referral centre for airway surgery
Authors: Naik Swapna , Saraf Sujit , Ghodki Poonam , Bapat Sunil 
Published: February 2023

ABSTRACT

Background and Aims:
Anaesthesia for endolaryngeal surgery is specialised to provide almost a tubeless surgical field. During the coronavirus disease-19 pandemic, when most of the surgeries were staggered, we being in a tertiary referral centre for airway surgery had to modify our existing techniques and observed an evolution in the anaesthesia management which we could continue even in the postpandemic period. Hence, we conducted this retrospective study to analyse the reliability of our locally developed apnoeic high-flow oxygenation technique (AHFO) for endolaryngeal procedures.

Methods:
We conducted this single-centric retrospective study from January 2020 to August 2021 to observe the choice of airway management techniques in endolaryngeal surgery and assess the feasibility and safety of AHFO. We also intend to propose an algorithm for airway management. We calculated the percentages of all necessary parameters to denote the trend in change of practices roughly classifying the study period as prepandemic, pandemic and postpandemic.

Results:
A total of 413 patients were analysed in our study. The changing trend over preference of AHFO from prepandemic (72%) and dominance of AHFO (92.5%) in the postpandemic period are the most significant observations of our study with 17% patients needing conversion to tube in-tube out technique due to desaturation which is comparable to 14% in prepandemic period.

Conclusion:
The tubeless field provided by AHFO replaced the conventional airway management techniques. Our study demonstrates the safety and feasibility of AHFO for endolaryngeal surgeries. We also propose an algorithm for anaesthetists involved in laryngology unit.
Impact on awareness and knowledge of resuscitation by structured training of compression-only life support (COLS) among non-medical staff
Authors: Kerketta Carolin Smita , Chhanwal Heena , Garg Rakesh , Diwan Rasesh 
Published: February 2023

ABSTRACT

Background and Aims:
This study intended to analyse the effectiveness of compression-only life support cardiopulmonary resuscitation (COLS CPR) training based on training knowledge acquired among non-medical staffs.

Methods:
The study was conducted among 300 non-medical staffs. Study design: It is an observational study where the effect of COLS CPR training was evaluated based on the pre-training and post-training assessment score. Google Forms questionnaire was used as an interventional tool. Participants in our study included security guards, ambulance drivers, housekeeping and facility staff of our hospital. Training was conducted for seven days through lecture, audio-visual display, demonstration and then hands-on session conducted at the end of each training. The Google Form questionnaires consisted of COLS meaning, rate, depth of compression, usefulness, etc. Corrective action preventive action (CAPA) analysis report was prepared along with corrective and preventive action, and onsite debriefing was also done.

Results:
Paired t-test was applied. For pre-test questions, 1,2,3,4,5 and 6 correct answers were 82.8%, 20.2%, 15%, 5%, >80% and <10%, respectively. In post-test, correct answers were 98.8%, 95%, 92.8%, 67%, 99.6% and 99.3%, respectively. P value 0.0022 suggested that training is highly effective and made statistically significant difference in knowledge of the participants.

Conclusion:
Among non-medical staff, this study emphasises the cognitive approach to the general perception and skill of COLS. Hence, formal refresher training and experience enhance the knowledge of CPR.
Functional Outcomes after Modified Blair’s Procedure for Ankle Arthritis Secondary to Hawkins Type III Talus Injuries: A Retrospective Cohort Study
Authors: Singh Shailendra , Rastogi Devarshi , Waliullah Shah , Singh Shitanshu Kumar , Ozair Ahmad 
Published: February 2023

Introduction:
The management of ankle arthritis secondary to traumatic talar injuries remains challenging, given the complexity of the majority of cases and the presentation of patients with avascular necrosis of the talus. While several treatment options have come up, the arthrodesis of the tibiotalar joint, as first described by Blair in 1943, remains a useful modality, especially in resource-limited settings. However, few studies have reported the functional outcome after the modified Blair’s procedure. This study sought to describe the functional outcomes after the modified Blair’s procedure for ankle arthritis secondary to Hawkins type III talus injuries.

Methods:
This retrospective cohort study was performed in a tertiary care center in northern India, which enrolled all patients with posttraumatic ankle arthritis due to Hawkins type III talus injuries who had received modified Blair’s ankle arthrodesis from January 2018 to January 2021. The primary outcomes were scores on the Visual Analog Scale (VAS) for pain and American Orthopaedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot Scale, which had been recorded both before treatment and 1-year postoperatively, and were compared through a paired t-test.

Results:
A total of 11 patients were included. Bony fusion occurred in a mean ± standard deviation duration of 21.73 ± 1.90 weeks. AOFAS score improved preoperatively from 41.45 ± 6.56 to 80.09 ± 5.09 at 1-year postoperatively (mean difference: 38.64, 95% confidence interval [CI]: 34.24–43.03, P < 0.001). VAS score for pain improved from 6.27 ± 1.10 preoperatively to 0.73 ± 0.78 1-year postoperatively (mean difference: 5.54, 95% CI: 4.85–6.24, P < 0.001).

Conclusions:
Modified Blair’s procedure has the potential to provide patients of posttraumatic ankle arthritis with significant pain relief and excellent functional outcomes. The remaining subtalar and talonavicular motion allows patients to have satisfactory walking ability without considerable difficulty.
Percutaneous endoscopic lumbar discectomy versus open lumbar microdiscectomy for treating lumbar disc herniation: Using the survival analysis
Authors: Lin Chang-Hao , Huang Yi-Hung , Lien Fang-Chieh , Wu Cheng-Yi , Chao Lin-Yu 
Published: February 2023

ABSTRACT

Objectives:
This study compared the risk of symptomatic recurrent disc herniation and clinical outcomes of percutaneous endoscopic lumbar discectomy (PELD) versus open lumbar microdiscectomy (OLM) for lumbar disc herniation with 2 years of follow-up.

Materials and Methods:
We analyzed 23 patients who underwent PELD and 32 patients who underwent OLM for lumbar disc herniation. The numeric rating scale of back and leg pain, Oswestry Disability Index (ODI), and Roland–Morris Disability Questionnaire (RMDQ) were assessed before and at 12 and 24 months after the surgery. The wound pain and complications were also recorded. Survival analysis was performed to estimate the risk of symptomatic recurrent disc herniation.

Results:
In the comparison of groups, the reductions in back and leg pain, ODI, and RMDQ were not significantly different at 12 and 24 months. For patients who underwent PELD, the wound pain was significant lower at the day of surgery. The survival rate of patients who were free from symptomatic recurrent disc herniation at 24 months was 0.913 in PELD and 0.875 in OLM, and the log-rank test revealed no significant difference between the two survival curves. The incidence of complication was not significantly different between groups.

Conclusion:
Both PELD and OLM are effective treatments for lumbar disc herniation because they have similar clinical outcomes. PELD provided patients with less painful wounds. The survival analysis revealed that the risk of symptomatic recurrent disc herniation in 2 years of follow-up was not different between PELD and OLM.
Physicochemical Characteristics and Fish Abundance and Diversity of Mairua Reservoir Water, Funtua, Katsina State, North-Western Nigeria
Authors: Lawal N. , Abdullahi S. A. , Abolude D. S. 
Published: February 2023

This research explores physico-chemical characteristics and fish abundance and diversity of Mairua Reservoir Water, Funtua, Katsina State, North-Western Nigeria. The duration of the study was 12 months starting from September to August, 2017, using standard methods and procedures.The result revealed that; Water temperature (25.02 ± 0.170C) pH (7.54 ± 0.03), Alkalinity (3.69±0.09), Conductivity (129.43 ± 5.15μЅ/cm), Total Dissolved Solids (50.54 ± 0.57mg/L) Nitrate-nitrogen (0.21 ± 0.04mg/L), Water Hardness (134.44 ± 3.06mg/LCaCO3), Dissolved Oxygen (3.98 ± 0.10mg/L),Biochemical Oxygen Demand (2.53 ± 0.08mg/L), Phosphate-phosphorus (0.19 ± 0.02mg/L),Chloride (5.09 ± 0.15mg/L),Sulphur-sulphate (0.21± 0.01) and Calcium (2.97±0.06mg/L) respectively were all varied with months and seasons. Analysis of variance indicated significant difference between seasons (P < 0.05).Out of the total number of fish species (8273) identified; the result indicated Fish fauna percentage composition were Coptodon zillii: 1980 (23.9%), Clarias gariepinus: 1560 (18.9%), Oreochromis niloticus: 1020 (12.3%), Lates niloticus: 860 (10.4%), Bagrus. Bayad: 632 (7.6 %), Mormyrus senegalensis: 973 (11.8%), Labeo senegalensis: 595 (7.2%) and Synodontis clarias: 650 (7.9%). Results also indicates most of fish species were positively correlated with the water quality parameters in all the sites studied. Hence, there were fish abundance and a sustainable livelihood amongst the fishermen. However, a careful management strategy and routine monitoring from both government and non-governmental organizations are critical for the improvement and sustenance of the fisheries resources of the reservoir.
Determinants of Information Communication Technology Accessibility for Community Development Activitiesamong Male and Female Agriculture Extension Workersin Edo State, Nigeria
Authors: Osabuohien J. I. , Okoedo-Okojie D. U. , Erhaze K. 
Published: February 2023

This study identified the determinants of (information communication Technology) ICTs accessibility among male and female agriculture extension workers for community development activities in Edo State, Nigeria. Primary data were collected from randomly selected one hundred and twenty-five (125) agricultural extension workers with the use of validated questionnaire. Means and Pearson’s Product Moment Correlation (PPMC) statistics were used as analytical tools. Results showed that the mean deviations of gender of agriculture extension workers in terms of age ( = 1.4), household size ( = 0.2), years of training ( = 0.4), and job experience ( = 0.7) were nuance. PPMC results showed that male and female agriculture extension workers age (r = -0.32; r = -0.31) and female job experience (r = 0.29) were the significant correlates of accessibility of ICTs at 5% significance level while male and female agriculture extension workers age (male r=0.32; female r =0.31), years of training (male r= 0.63, female r=0.55), and male job experience (r=0.39) correlated with their accessibility to ICTs at 0.01 level of significance. The study recommends that agriculture extension institutions should make adequate provisions for staffs to take care of their household members which will in turn enable them pay much attention to official work and have sufficient time to access ICTs facilities. Also, young people should be employedto carry out extension works since they have higher accessibility to ICTs than older staffs.
Production of Bioflocculant through Fermentation of Spoilt Orange Juice with Bacillus spp Isolated from Sediment of Local Clay Pot
Authors: Mohammed J. N. , Majiya H. , Adisa J. M. , Kassim Z. J. 
Published: February 2023

The biodegradable and non-toxic Bioflocculants have attracted considerable interest as alternative to non-biodegradable chemical flocculants. However, the cost of fermentation media for bioflocculant production and low flocculation efficiency is a major challenge. In this study, we grow Bacillus spp isolated from sediment of local clay pot on spoilt orange juice to produce bioflocculant. The culture supernatant of the bacilli grown on spoilt orange juice were screen for bioflocculant production using Jar test method and Kaolin clay suspension as model wastewater. The effect of pH and temperature on the bioflocculant production were also studied. The effect of cations on bioflocculation rate of the bioflocculant produced were tested via hybridization of the bioflocculant with the cations. The bioflocculation efficiency of the bioflocculant on sample wastewaters were also determined. The bacilli isolated initially had flocculation rate between 31.1±1.6 % to 76.4±1.2% when cultured on screening media. Bioflocculation rate peaked to 77.9% at 40 oC while the lowest flocculation rate (55.41%) was obtained at 25 oC. The optimum bioflocculant production (about 78%) was recorded at pH 6 – 7 while the highest bioflocculant production (84.2%) was achieved at 96th hour of incubation. Na+ and Fe3+ had serious inhibitory effect on the bioflocculant while K+, Ca2+, Mg2+ and Al3+ had less or no effect on the bioflocculant. The bioflocculant had up to 77.7% and 64.5 % on Kitchen wastewater and aquaculture wastewater. This study reveals the potential for utilization of spoilt orange juice as fermentable substrate for bioflocculant production especially if the fermentation conditions and flocculation parameters are well optimized.
PENGARUH BUDAYA ORGANISASI TERHADAP KINERJA KARYAWAN DENGAN KEPUASAN SEBAGAI VARIABEL MEDIASI PADA LEMBAGA PERKREDITAN DESA DI KABUPATEN BADUNG
Authors: Artini Ni Rai Rai , Pynatih Ngurah Made Novianha , Ayuk Ni Made Taman 
Published: February 2023

AbstrakLembaga Perkreditan Desa merupakan lembaga keuangan milik Desa pakraman yang telah berkembang, memberikan manfaat sosial, ekonomi, dan budaya kepada anggotanya sehingga perlu dibina, ditingkatkan, dan dilestarikan keberadaannya. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh langsung atau tidak langsung budaya organisasi terhadap kinerja karyawan terhadap kepuasan kerja. Lokasi penelitian ini dilakukan pada Lembaga Perkreditan Desa di Kabupaten Badung yang berjumlah 122 LPD. Data dikumpulkan secara cross-section melalui kuesioner dengan skala likert. Respondennya adalah karyawan LPD sebanyak 94 responden. Teknik pengambilan sampel menggunakan Proportionate Stratified Random Sampling. Metode analisis data yang digunakan untuk pengujian hipotesis adalah analisis jalur (path analysis). Berdasarkan hasil analisis diketahui bahwa : 1) budaya organisasi berpengaruh langsung positif dan signifikan terhadap kinerja karyawan pada LPD di Kabupaten Badung, 2) budaya organisasi berpengaruh langsung positif dan signifikan terhadap kepuasan kerja pada LPD di Kabupaten Badung, 3) budaya organisasi berpengaruh tidak langsung dan signifikan terhadap kinerja karyawan pada LPD di Kabupaten Badung melalui kepuasan kerja dan 4) kepuasan kerja berpengaruh langsung positif dan signifikan terhadap kinerja karyawan pada LPD di Kabupaten Badung.