bluuebunny/crossref_metadata_2025_split huggingface dataset:
Self‐Healable, Self‐Adhesive Conductive Hydrogels Based on Integrated Multiple Interactions for Wearable Sensing
Authors: Lu Xinyi , Li Yunlong , Gu Xiaochun , Zhang Xinyue , Ma Ning 
Published: August 2023

AbstractWith the development of the medical and health industry, new health monitoring devices have attracted a lot of attention. By placing sensors in different organs, intelligent detection of human behavior and diagnosis of physical health can be achieved. Traditional electronic sensor devices have huge deficiencies in capturing tiny stimulus signals and comfort. Wearable sensors based on flexible conductive hydrogels are the most promising candidates for conventional sensors. However, the development of conductive hydrogels with good self‐healing and adhesion properties is still a challenge. Herein, a flexible polyvinyl alcohol hydrogel is prepared with good self‐healing properties, self‐adhesive and conductive properties based on polyvinyl alcohol, sodium phytate solution, and borax using a simple method. The abundant hydrogen bonding interactions, dynamically reversible borate ester bonds in the hydrogel network endowed the hydrogel with good self‐healing properties, self‐adhesion, and electrical conductivity. The fractured hydrogels showed almost disappearance of cracks after 30 min of self‐healing, and the efficiency of electrochemical repair within 0.1 s is close to 100%. The hydrogels can achieve good adhesion to different substrates and can be used as flexible writable circuits and smart wearable sensors, which have promising applications in the fields of flexible electronics, smart sensing, and health monitoring.
Parkinson's Disease Tremor Differentially Responds to Levodopa and Subthalamic Stimulation
Authors: Wirth Thomas , Ferreira Francisca , Vijiaratnam Nirosen , Girges Christine , Pakzad Ashkan , de Roquemaurel Alexis , Sinani Olga , Hyam Jonathan , Hariz Marwan , Zrinzo Ludvic , Akram Harith , Limousin Patricia , Foltynie Thomas 
Published: August 2023

AbstractBackgroundTremor in Parkinson's disease (PD) has an inconsistent response to levodopa and subthalamic deep brain stimulation (STN‐DBS).ObjectivesTo identify predictive factors of PD tremor responsiveness to levodopa and STN‐DBS.Material and MethodsPD patients with upper limb tremor who underwent STN‐DBS were included. The levodopa responsiveness of tremor (overall, postural, and rest sub‐components), was assessed using the relevant Unified Parkinson's Disease Rating Scale‐III items performed during the preoperative assessment. Post‐surgical outcomes were similarly assessed ON and OFF stimulation. A score for the rest/postural tremor ratio was used to determine the influence of rest and postural tremor severity on STN‐DBS outcome. Factors predictive of tremor responsiveness were determined using multiple linear regression modeling. Volume of tissue activated measurement coupled to voxel‐based analysis was performed to identify anatomical clusters associated with motor symptoms improvement.ResultsOne hundred and sixty five patients were included in this study. Male gender was negatively correlated with tremor responsiveness to levodopa, whereas the ratio of rest/postural tremor was positively correlated with both levodopa responsiveness and STN‐DBS tremor outcome. Clusters corresponding to improvement of tremor were in the subthalamic nucleus, the zona incerta and the thalamus, whereas clusters corresponding to improvement for akinesia and rigidity were located within the subthalamic nucleus.ConclusionMore severe postural tremor and less severe rest tremor were associated with both poorer levodopa and STN‐DBS response. The different locations of clusters associated with best correction of tremor and other parkinsonian features suggest that STN‐DBS effect on PD symptoms is underpinned by the modulation of different networks.
Der richtige Dreh: Helicene enantioselektiv synthetisieren
Authors: Imse Nils , Simeth Nadja A. 
Published: August 2023

AbstractHelicene erzeugen starke asymmetrische Effekte – vorausgesetzt, man gewinnt sie enantiomerenrein. Forschungsgruppen haben nun Wege gefunden, um Helicene und Heterohelicene asymmetrisch herzustellen.
Energiewende: Was zu beachten und zu tun ist
Authors: von Heimburg Joachim , Roduner Emil , Franz Klaus‐Dieter , Huebinger Wolfgang , Osterland Thomas 
Published: August 2023

AbstractDie Chemie als Industrie und Wissenschaft braucht Energie und Kohlenstoffquellen, stößt Treibhausgase aus und bietet gleichzeitig Innovationen, Emissionen zu reduzieren. Sektoren wie Stromerzeugung, Produktion, Verkehr und Wärme müssen interdisziplinär zusammenarbeiten und Maßnahmen priorisieren, um CO2‐Emissionen zu senken.
Trendbericht Biochemie 2023 (1/3): Sequenzierung von epigenetischen DNA‐Basen
Authors: Becker Sidney , Ogel Eric 
Published: August 2023

AbstractFortschritte bei der Analyse epigenetischer Basen helfen unter anderem dabei, Krankheiten früher zu diagnostizieren. In Inneren von Encapsulinen, das sind proteinbasierte Nanocapside, laufen (bio)chemische Reaktionen geschützt ab, sie können daher für die Katalyse genutzt werden. Deuterierung von Fluoreszenzfarbstoffen erhöht deren Extinktion, Fluoreszenzlebensdauer und Helligkeit, sodass sich die deuterierten Farbstoffe besser für hochauflösende Mikroskopiemethoden eignen.
Inhoffen‐Vorlesung in Braunschweig
Authors: Schulz Stefan 
Published: August 2023

AbstractIn einer gemeinsamen Veranstaltung des Helmholtz‐Zentrums für Infektionsforschung (HZI) und der TU Braunschweig hielt Jörn Piel von der ETH Zürich am 8. Juni die Hans‐Herloff‐Inhoffen‐Vorlesung.
Subcellular proteomics insights into Alzheimer's disease development
Authors: Liang Zhiyuan , Zhuang Hongbin , Cao Xueshan , Ma Guanwei , Shen Liming 
Published: August 2023

AbstractAlzheimer's disease (AD), one of the most common dementias, is a neurodegenerative disease characterized by cognitive impairment and decreased judgment function. The expected number of AD patient is increasing in the context of the world's advancing medical care and increasing human life expectancy. Since current molecular mechanism studies on AD pathogenesis are incomplete, there is no specific and effective therapeutic agent. Mass spectrometry (MS)‐based unbiased proteomics studies provide an effective and comprehensive approach. Many advances have been made in the study of the mechanism, diagnostic markers, and drug targets of AD using proteomics. This paper focus on subcellular level studies, reviews studies using proteomics to study AD‐associated mitochondrial dysfunction, synaptic, and myelin damage, the protein composition of amyloid plaques (APs) and neurofibrillary tangles (NFTs), changes in tissue extracellular vehicles (EVs) and exosome proteome, and the protein changes in ribosomes and lysosomes. The methods of sample separation and preparation and proteomic analysis as well as the main findings of these studies are involved. The results of these proteomics studies provide insights into the pathogenesis of AD and provide theoretical resource and direction for future research in AD, helping to identify new biomarkers and drugs targets for AD.
Multivalent Targeting of the Asialoglycoprotein Receptor by Virus‐Like Particles
Authors: Hincapie Robert , Bhattacharya Sonia , Baksh Michael M. , Sanhueza Carlos A. , Echeverri Elisa Schrader , Kim Hyejin , Paunovska Kalina , Podilapu Ananda R. , Xu Minghao , Dahlman James E. , Finn M. G. 
Published: August 2023

AbstractThe asialoglycoprotein receptor (ASGPR) is expressed in high density on hepatocytes. Multivalent variants of galactosyl carbohydrates bind ASGPR with high affinity, enabling hepatic delivery of ligand‐bound cargo. Virus‐like particle (VLP) conjugates of a relatively high‐affinity ligand were efficiently endocytosed by ASGPR‐expressing cells in a manner strongly dependent on the nature and density of ligand display, with the best formulation using a nanomolar‐, but not a picomolar‐level, binder. Optimized particles were taken up by HepG2 cells with greater efficiency than competing small molecules or the natural multigalactosylated ligand, asialoorosomucoid. Upon systemic injection in mice, these VLPs were rapidly cleared to the liver and were found in association with sinusoidal endothelial cells, Kupffer cells, hepatocytes, dendritic cells, and other immune cells. Both ASGPR‐targeted and nontargeted particles were distributed similarly to endothelial and Kupffer cells, but targeted particles were distributed to a greater number and fraction of hepatocytes. Thus, selective cellular trafficking in the liver is difficult to achieve: even with the most potent ASGPR targeting available, barrier cells take up much of the injected particles and hepatocytes are accessed only approximately twice as efficiently in the best case.
Preferred Orientation Deposition via Multifunctional Gel Electrolyte with Molecular Anchor Enabling Highly Reversible Zn Anode
Authors: Xu Yu‐Ting , Dai Sheng‐Jia , Gong Ming‐Jun , Zhang Ji‐Zun , Xu Hai , Li Aijun , Sasaki Shin‐ichi , Zeng Xian‐Xiang , Wu Xiong‐Wei , Wang Xiao‐Feng 
Published: August 2023

AbstractThe high activity of water molecules results in a series of awful parasitic reaction, which seriously impede the development of aqueous zinc batteries. Herein, a new gel electrolyte with multiple molecular anchors is designed by employing natural biomaterials from chitosan and chlorophyll derivative. The gel electrolyte firmly anchors water molecules by ternary hydrogen bonding to reduce the activity of water molecules and inhibit hydrogen evolution reaction. Meanwhile, the multipolar charged functional groups realize the gradient induction and redistribution of Zn2+, which drives oriented Zn (002) plane deposition of Zn2+ and then achieves uniform Zn deposition and dendrite‐free anode. As a result, it endows the Zn||Zn cell with over 1700 h stripping/plating processes and a high efficiency of 99.4% for the Zn||Cu cell. In addition, the Zn||V2O5 full cells also exhibit capacity retention of 81.7% after 600 cycles at 0.5 A g−1 and excellent long‐term stability over 1600 cycles at 2 A g−1, and the flexible pouch cells can provide stable power for light‐emitting diodes even after repeated bending. The gel electrolyte strategy provides a reference for reversible zinc anode and flexible wearable devices.
The Enhancement Mechanism of Different Single‐Transition Metal Atomic Catalysts/Sulfur Cathode on High‐Performance of Li–S Batteries
Authors: Wu Chao , Wu Jinggao , Li Juan , Zou Zhuo , Yang Hong Bin , Wu Xiaoshuai , Zeng Qingxin , Dai Fangyin , Sun Wei , Li Chang Ming 
Published: August 2023

AbstractMaterials with various single‐transition metal atoms dispersed in nitrogenated carbons (M─N─C, M = Fe, Co, and Ni) are synthesized as cathodes to investigate the electrocatalytic behaviors focusing on their enhancement mechanism for performance of Li–S batteries. Results indicate that the order of both electrocatalytic activity and rate capacity for the M─N─C catalysts is Co > Ni > Fe, and the Co─N─C delivers the highest capacity of 1100 mAh g−1 at 1 C and longtime stability at a decay rate of 0.05% per cycle for 1000 cycles, demonstrating excellent battery performance. Theoretical calculations for the first time reveal that M─N─N─C catalysts enable direct conversion of Li2S6 to Li2S rather than Li2S4 to Li2S by stronger adsorption with Li2S6, which also has an order of Co > Ni > Fe. And Co─N─C has the strongest adsorption energy, not only rendering the highest electrocatalytic activity, but also depressing the polysulfides’ dissolution into electrolyte for the longest cycle life. This work offers an avenue to design the next generation of highly efficient sulfur cathodes for high‐performance Li–S batteries, while shedding light on the fundamental insight of single metal atomic catalytic effects on Li–S batteries.
Bridging Theory to Practice: Exploring the Role of an Educative Translingual Curriculum to Support Linguistically Diverse Classroom Practices
Authors: White Holland , Galloway Emily Phillips , Jiménez Robert T. 
Published: August 2023

AbstractThis study investigates how five teachers of multilingual learners (MLLs), working in an officially English‐centric school district, make sense of a reading curriculum based in translingual pedagogies, or instruction that builds on language and languaging practices (e.g., language brokering, translation, and codemeshing) familiar to multilingual youth. Participating teachers, describing themselves as mostly monolingual educators, utilized the curriculum during a support class for their MLLs. We show how this curriculum, containing what we classify as educative curriculum materials (Davis & Krajcik, 2005), operated to support, and extend linguistically supportive instructional practices occurring within participating teachers' classroom figured worlds (Holland et al., 1998). Using data from classroom observations and teacher interviews, we show how the curriculum operated as a mediating artifact to support teachers' development of more linguistically diverse practices within their classrooms. Findings indicate that curriculum materials bridged theory to practice by supporting teacher development of these practices, which, in turn, bolstered their beliefs in the importance of students' home languages, and led to a shift in how teachers understood, interpreted, and resisted English‐centric policies at their schools.
Political Remittances: The Post-war Transformation of the Tamil Swiss Diaspora
Authors: Alluri Rina Malagayo 
Published: August 2023

AbstractThis chapter explores how the practice of remittances has been used as a form of political activism. The case study looks at the role of remittances in the transnational Sri Lankan Tamil diaspora broadly and the Swiss-based second-generation diaspora specifically. It shows that while political remittances were used during the Sri Lankan civil war as a way to sustain and perpetuate the violence conflict between the Government of Sri Lanka and the Liberation Tigers of Tamil Eelam (LTTE), the role of remittances in the diaspora since the end of the war has changed and, in some ways, become depoliticized.
Receiving the Gift of the Master’s Voice: How White Western Academic Paradigms Shape Knowledge and Remittance Economies: A De-Colonial Perspective
Authors: Bönisch-Brednich Brigitte 
Published: August 2023

AbstractThis chapter explores the social, political, and cultural agents that drive the engines of gifting academic knowledge. It considers knowledge as a form of social remittance. Viewing knowledge transfers as remittance practices makes processes of (neo)colonial exchange flows visible. It also allows us to see such remittances as what they are: political and social scripts that determine legitimacy, value, and currency of knowledge in a world of economic and social inequalities. We can view knowledge according to Bourdieu as academic capital with skewed exchange rates. This chapter explores the question: How are the positions of sender and receiver linked to neo-colonial inequities? In a world system of university rankings, regionalized hubs of academic influence, money flows, and uneven power relationships, the exchange of knowledge and the definition of what constitutes knowledge is a fraught and fascinating topic when approaching it within a frame of remittance economy.
“You Can’t Have Your Pudding and Eat It”? Remittances and Development in Yugoslavia, 1918–1989
Authors: Miletić Aleksandar R. 
Published: August 2023

AbstractThis chapter explores the governmental remittance-related development strategies in monarchist and socialist Yugoslavia. It analyzes administrative practices and language regarding the actual or envisaged utilization of remittances. It stresses in particular the policymakers’ misconception regarding the nature of remittances as being private and not a disposable public resource as they assumed. This assumption facilitated grand yet impossible developmental designs based on an anticipated transformative impact of remittances. By establishing a comparative perspective with corresponding Turkish developments in the 1970s and 1980s, this chapter investigates whether the Yugoslav economic failure or Turkish relative success of the 1980s can be related to their previous histories of remittance management.
“We Do Solidarity, Not Charity”: The Collective Remittance Practices of Moldovan Migrants
Authors: Odermatt Eveline 
Published: August 2023

AbstractThis chapter provides an insight into how the discourse of migrants’ contributions to developmental transition is put into concrete practice in the case of Moldova. It highlights Moldovan migrants’ subjective motivations to engage in collective transnational aid efforts, understood as transnational practices, such as return visits and cross-border communication. It draws from 84 interviews with migrants and development actors as well as from ethnographic work conducted in transnational Moldovan migrant civil society and in the international aid and development sector across seven countries: Belgium, France, Germany, Italy, Moldova, Switzerland, and the UK. The main argument is that collective remittance practices emerge from both the migrants’ everyday lives, connecting multiple localities, and their past and current visions of their home country. Thereby, the chapter contributes to the broader theoretical discussion on linkages between the patterns of collective remitting by Eastern European migrants living in EU countries and the development transition in the Eastern European “neighborhood.”
Latino and Asian Segregation in New Destinations
Authors: Crowell Amber R. , Fossett Mark A. 
Published: August 2023

AbstractOver the past several decades, hundreds of large and small communities across the United States saw Latino and Asian migration and population growth for the first time as Latino and Asian migrants moved away from traditional “gateway” cities and regions. This phenomenon has raised questions among researchers about how these new groups are being received in what are often predominately White communities, and in particular whether residential segregation patterns are emerging. While some have studied the residential segregation of “new destinations,” these endeavors have been limited by the methodological challenges highlighted and addressed in this book. Because many of these communities are also nonmetropolitan, issues with index bias are pronounced due to small population counts and imbalanced group sizes. In this chapter, we reexamine residential segregation in Latino and Asian new destination communities, and also consider the possibility of Black new destinations, from 1990 to 2010 across metropolitan and micropolitan areas and noncore counties in the United States. Three key methodological innovations bring about new findings on residential segregation patterns and trends in these communities: we correct for segregation index bias, rely on the separation index to assess uneven distribution, and measure segregation of households rather than persons. In general we find that segregation is initially low and dispersed in new destination communities but is rising and polarizing over time for some groups, particularly in Latino new destinations. This is in contrast to previous studies that sometimes found high levels of segregation in Latino new destinations, with scores sometimes as high as those found in the most segregated metropolitan areas. Our adjustments to measuring residential segregation are critical for obtaining an accurate understanding of how residential segregation outcomes are unfolding in new destination communities.
Einleitung
Authors: Engelhardt Monika , Mertelsmann Roland , Duyster Justus 
Published: August 2023

ZusammenfassungDas Kapitel 1 gibt einen Überblick über den Inhalt und die Struktur der verfügbaren Buchversionen: Druckwerk, eBook und Zusatzmaterial, welches dem Buch-/Kapitel-Käufer zur Verfügung steht. Der Leser erhält wichtige, allgemein gültige Hinweise und Tipps zum praktischen Gebrauch der Protokollsammlung. Exemplarisch für ein gut funktionierendes und sicheres Chemotherapie-Bestellsystem wird der Ablauf des interdisziplinären Chemotherapiemanagements am Universitätsklinikum Freiburg beschrieben. Zudem finden sich ausführliche Tabellen mit Empfehlungen zu Dosismodifikationen bei eingeschränkter Nieren- bzw. Leberfunktion oder für Patienten unter Hämodialyse für nahezu alle abgedruckten Substanzen.
Immunthrombozytopenie
Authors: Engelhardt Monika , Mertelsmann Roland , Duyster Justus 
Published: August 2023

ZusammenfassungDas Kapitel 11 beinhaltet eine Zusammenstellung der am Universitätsklinikum Freiburg verwendeten Tumortherapie- und ggf. Studien-Protokolle der Entität Immunthrombozytopenie. Der Kapitelinhalt orientiert sich an aktuellen Leitlinien und Therapieempfehlungen und spiegelt detailliert die Therapieabläufe inkl. Supportivtherapie der Freiburger Praxis wider.Beim Erwerb von Einzelkapiteln muss folgendes beachtet werden:

Protokolle, die bei mehreren Entitäten angewandt werden können, sind aus technischen Gründen nur in jeweils einem Kapitel enthalten. Deshalb muss unter Umständen das Gesamtwerk konsultiert werden.

Erläuterungen zum praktischen Gebrauch der Protokollsammlung inkl. Dosismodifikationstabellen befinden sich im Kapitel 1 (Einleitung).
Thymuskarzinom
Authors: Engelhardt Monika , Mertelsmann Roland , Duyster Justus 
Published: August 2023

ZusammenfassungDas Kapitel 14 beinhaltet eine Zusammenstellung der am Universitätsklinikum Freiburg verwendeten Tumortherapie- und ggf. Studien-Protokolle der Entität Thymuskarzinom. Der Kapitelinhalt orientiert sich an aktuellen Leitlinien und Therapieempfehlungen und spiegelt detailliert die Therapieabläufe inkl. Supportivtherapie der Freiburger Praxis wider. Beim Erwerb von Einzelkapiteln muss folgendes beachtet werden:Beim Erwerb von Einzelkapiteln muss folgendes beachtet werden:

Protokolle, die bei mehreren Entitäten angewandt werden können, sind aus technischen Gründen nur in jeweils einem Kapitel enthalten. Deshalb muss unter Umständen das Gesamtwerk konsultiert werden.

Erläuterungen zum praktischen Gebrauch der Protokollsammlung inkl. Dosismodifikationstabellen befinden sich im Kapitel 1 (Einleitung).
Gastrointestinale Tumoren
Authors: Engelhardt Monika , Mertelsmann Roland , Duyster Justus 
Published: August 2023

ZusammenfassungDas Kapitel 15 beinhaltet eine Zusammenstellung der am Universitätsklinikum Freiburg verwendeten Tumortherapie- und ggf. Studien-Protokolle der Entität Gastrointestinale Tumoren. Dieses ist in die Unterkapitel Plattenepithelkarzinom des Ösophagus, Adenokarzinom des Ösophagus und des ösophagogastralen Übergangs (AEG-Tumor) und Magenkarzinom, Kolon- und Rektumkarzinom, Analkarzinom, Pankreaskarzinom, Cholangiozelluläres Karzinom, Hepatozelluläres Karzinom (HCC), Gastrointestinale Stromatumoren (GIST), Neuroendokrine Tumoren des Gastrointestinaltraktes (NET) und Neuroendokrine Karzinome des Gastrointestinaltraktes (NEC) gegliedert. Der Kapitelinhalt orientiert sich an aktuellen Leitlinien und Therapieempfehlungen und spiegelt detailliert die Therapieabläufe inkl. Supportivtherapie der Freiburger Praxis wider.Beim Erwerb von Einzelkapiteln muss folgendes beachtet werden:

Protokolle, die bei mehreren Entitäten angewandt werden können, sind aus technischen Gründen nur in jeweils einem Kapitel enthalten. Deshalb muss unter Umständen das Gesamtwerk konsultiert werden.

Erläuterungen zum praktischen Gebrauch der Protokollsammlung inkl. Dosismodifikationstabellen befinden sich im Kapitel 1 (Einleitung).