bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does adding MRI and CSF-based biomarkers improve cognitive status classification based on cognitive performance questionnaires?
Authors: Farina Mateo P. , Saenz Joseph , Crimmins Eileen M. 
Published: May 2023

Background
Cognitive status classification (e.g. dementia, cognitive impairment without dementia, and normal) based on cognitive performance questionnaires has been widely used in population-based studies, providing insight into the population dynamics of dementia. However, researchers have raised concerns about the accuracy of cognitive assessments. MRI and CSF biomarkers may provide improved classification, but the potential improvement in classification in population-based studies is relatively unknown.

Methods
Data come from the Alzheimer’s Disease Neuroimaging Initiative (ADNI). We examined whether the addition of MRI and CSF biomarkers improved cognitive status classification based on cognitive status questionnaires (MMSE). We estimated several multinomial logistic regression models with different combinations of MMSE and CSF/MRI biomarkers. Based on these models, we also predicted prevalence of each cognitive status category using a model with MMSE only and a model with MMSE + MRI + CSF measures and compared them to diagnosed prevalence.

Results
Our analysis showed a slight improvement in variance explained (pseudo-R2) between the model with MMSE only and the model including MMSE and MRI/CSF biomarkers; the pseudo-R2 increased from .401 to .445. Additionally, in evaluating differences in predicted prevalence for each cognitive status, we found a small improvement in the predicted prevalence of cognitively normal individuals between the MMSE only model and the model with MMSE and CSF/MRI biomarkers (3.1% improvement). We found no improvement in the correct prediction of dementia prevalence.

Conclusion
MRI and CSF biomarkers, while important for understanding dementia pathology in clinical research, were not found to substantially improve cognitive status classification based on cognitive status performance, which may limit adoption in population-based surveys due to costs, training, and invasiveness associated with their collection.
Adolescent screen time and unhealthy food consumption in the context of the digital development in New Caledonia
Authors: Nedjar-Guerre Akila , Wattelez Guillaume , Serra-Mallol Christophe , Frayon Stéphane , Galy Olivier 
Published: May 2023

Objective
For several years, the Pacific Island Countries and Territories (PICTs) have been undergoing digital developments that have had an impact on the time adolescents spend in front of screens. The association between screen time and the overconsumption of unhealthy foods has been observed but little studied in New Caledonia. The twofold aim of this research was to analyze adolescent screen time based on the number of screens at home, gender, place of living, ethnic community and family socio-professional category and determine the link with the consumption of unhealthy food and drinks.

Methods
Self-report questionnaires on time spent in front of tablets, computers and mobile phones, as well as the consumption of unhealthy food and drinks, were administered between July 2018 and April 2019 to 867 adolescents from 11 to 15 years old during school hours in eight schools across the three provinces of New Caledonia.

Results
Adolescents in rural areas had fewer screens than their urban counterparts, and the number of screens determined the amount of screen time, which was significantly higher among the adolescents living in urban areas (3.05 h/day weekdays vs rural 2.33 h/day). Screen time was not related to gender, socio-professional category or ethnic community, but correlations were found between screen time and consumption of unhealthy food and drinks. Those who consumed less than 1 u/day of unhealthy drinks watched screens for 3.30 h/day, whereas those who consumed more than 1 u/day watched screens for 4.13 h/day. Also, those who consumed less than 1 u/day of unhealthy food watched screens for 2.82 h/day and those consuming more than 1 u/day did so for 3.62 h/day. Melanesians and Polynesians consumed greater quantities of unhealthy food and drinks than Europeans. As the consumption of unhealthy products is linked to screen time in the context of digital development, there is an urgent need to address the excessive consumption of unhealthy foods in Oceanian populations, particularly among young people.
Etiology and outcome of penetrating keratoplasty in bullous keratopathy post-cataract surgery vs post-glaucoma surgery
Authors: Jung Young-ho , Choi Hyuk Jin , Kim Mee Kum , Oh Joo Youn 
Published: May 2023

Purpose
To investigate the causes of bullous keratopathy (BK) in the Korean population and analyze the results of penetrating keratoplasty (PK) in BK eyes associated with the top two causes: pseudophakic bullous keratopathy (PBK) and glaucoma surgery-associated BK (GBK).

Methods
Medical records were reviewed of patients diagnosed with BK at a tertiary referral center between 2010 and 2020. The predisposing conditions, clinical characteristics and therapeutic outcomes after PK were analyzed and compared.

Results
Of total 340 BK eyes, 70% (238 eyes) were associated with ocular surgery; most commonly, cataract surgery (48%, 162 eyes) and glaucoma surgery/laser (21%, 70 eyes). The BK onset was faster following glaucoma surgery/laser (91.7 ± 94.4 months) than following cataract surgery (160.7 ± 138.0 months, p < 0.001). The median survival time of allografts was shorter in GBK than in PBK (24.0 vs 51.0 months, p = 0.020). Best-corrected logMAR visual acuities were lower in GBK than in PBK after PK (1.4 ± 0.7 vs 0.9 ± 0.6, p = 0.017 at one year; 1.8 ± 0.7 vs 1.1 ± 0.8, p = 0.043 at three years).

Conclusions
Intraocular surgery is the major predisposing condition of BK in Korea. GBK developed earlier and its therapeutic outcome was poorer, compared to PBK.
Factors associated with underutilization of antenatal care in India: Results from 2019–2021 National Family Health Survey
Authors: Thakkar Nandan , Alam Prima , Saxena Deepak 
Published: May 2023

IntroductionDespite progress in recent years, full antenatal care utilization in India continues to be relatively low and inequitable, particularly between states and districts. In 2015–2016, for example, only 51% of women aged 15–49 in India attended antenatal care at least four times during pregnancy. Using data from the fifth iteration of India’s National Family Health Survey, our study aims to explore factors related to the underutilization of antenatal care in India.Materials and methodsData from the most recent live birth in the past five years among women aged 15–49 years were included in our analysis (n = 172,702). Our outcome variable was “adequate antenatal care visits”, defined as four or more antenatal visits. Utilizing Andersen’s behavioral model, 14 factors were identified as possible explanatory variables. We used univariate and multivariate binary logistic regression models to analyze the association between explanatory variables and adequate visits. Associations were considered statistically significant if p<0.05.ResultsOf the 172,702 women in our sample, 40.75% (95% CI: 40.31–41.18%) had an inadequate number of antenatal care visits. In multivariate analysis, women with less formal education, from poorer households and more rural areas had higher odds of inadequate visits. Regionally, women from Northeastern and Central states had higher odds of inadequate antenatal care utilization compared to those from Southern states. Caste, birth order, and pregnancy intention were also among the variables associated with utilization of antenatal care.DiscussionDespite improvements in antenatal care utilization, there is cause for concern. Notably, the percentage of Indian women receiving adequate antenatal care visits is still below the global average. Our analysis also reveals a continuity in the groups of women at highest risk for inadequate visits, which may be due to structural drivers of inequality in healthcare access. To improve maternal health and access to antenatal care services, interventions aimed at poverty alleviation, infrastructure development, and education should be pursued.
Between high hopes and disappointments: Community-Based tourism in Prainha do Canto Verde, Beberibe - CE
Authors: Silva João Paulo 
Published: May 2023

This study analyzes the territorial repercussions of the development of Community-Based Tourism (CBC) in the Resex region of Prainha do Canto Verde, a community located in the municipality of Beberibe, on the coast of the State of Ceará, Brazil. This initiative is one of fifty CBT projects supported by Public Notice No. 001/2008 of the Ministry of Tourism. The analysis carried out considered some important dimensions for the structuring of the tourism modality discussed here, such as popular participation, the relationship between the community and the inducing agent, the project management model and the socio-spatial conflicts that arise with the development of tourism in the territory. To this end, bibliographic and documentary research was carried out on works produced on the fifty CBT projects supported in 2008, in addition to field research in Prainha in 2020 and semi-structured interviews, carried out remotely with representatives of the Rede Cearense de Turismo Comunitário (TUCUM) throughout 2021. The study promotes the understanding of CBT as a means of promoting community participation in the process of constructing, operating, managing and monitoring tourist activity in territories that present social and economic vulnerabilities, generally characterized as traditional communities.
PENAMBAHAN GUM ARAB DENGAN KONSENTRASI YANG BERBEDA TERHADAP KANDUNGAN SENYAWA VOLATIL BUBUK RUSIP IKAN TERI (Stolephorus sp.)
Authors: Susianti Susianti , Amalia Ulfah , Rianingsih Laras 
Published: May 2023

Rusip merupakan produk fermentasi ikan dengan menggunakan bahan baku ikan yang berukuran kecil seperti ikan teri dan memiliki aroma manis khas yang berfungsi sebagai bumbu masakan. Pengolahan rusip menjadi bubuk mengakibatkan komponen senyawa volatil dapat hilang sehingga diperlukan bahan untuk melindunginya salah satunya gum arab. Tujuan dari penelitian ini untuk mengetahui pengaruh penambahan gum arab terhadap senyawa volatil bubuk rusip dan mengetahui kandungan senyawa volatil yang terdapat pada bubuk rusip. Penelitian ini bersifat experimental laboratories model Rancangan Acak Lengkap dengan perlakuan konsentrasi gum arab yang berbeda yaitu 0%, 2,5%, 5% dan 7,5% dengan 3 kali pengulangan. Data parametrik (kadar asam glutamat, kadar protein dan kadar air) dianalisa menggunakan Anova BNJ, sedangkan data non parametrik (hedonik) menggunakan uji Kruskal Wallis. Hasil Anova BNJ menunjukkan gum arab berpengaruh terhadap bubuk rusip (P<5%) terhadap kadar asam glutamat, kadar protein dan kadar air. Penambahan gum arab terhadap senyawa volatil bubuk rusip berpengaruh terhadap kemunculan puncak dan area terbesar yaitu 62,51%. Senyawa volatil bubuk rusip dengan penambahan gum arab memberikan hasil yang lebih tinggi dengan kandungan senyawa volatil yang berasal dari golongan hidrokarbon, ester dan beberapa golongan lain seperti nitrogen. Hasil pada bubuk rusip dengan penambahan gum arab 5% merupakan perlakuan terbaik dengan kadar asam glutamat 13,44±0,06 mg, kadar protein 27,29±0,28% dan kadar air 8,24±0,03%. Tingkat penerimaan panelis terhadap bubuk rusip paling disukai pada konsentrasi 5% dengan rata-rata 8,10±0,48.
PENGHAMBATAN OKSIDASI LEMAK BAKSO IKAN LELE (Clarias batracus) DENGAN EDIBLE COATING KARAGENAN YANG DIPERKAYA MINYAK WIJEN
Authors: Inats Ashimatul , Dewi Eko Nurcahya , Purnamayati Lukita 
Published: May 2023

Tingginya kandungan lemak pada ikan lele menyebabkan bakso selama penyimpanan suhu ruang rentan terhadap kerusakan lemak. Edible coating merupakan salah satu alternatif yang mampu menghambat oksidasi lemak pada bakso ikan sebagai pembawa senyawa antioksidan dari minyak wijen. Tujuan dari penelitian ini untuk mengetahui apakah penambahan minyak wijen pada edible coating mampu memperpanjang daya simpan bakso pada suhu ruang. Bahan yang digunakan meliputi ikan lele, karagenan dan minyak wijen. Penelitian ini bersifat experimental laboratories model rancangan acak lengkap faktorial (2x5) dengan dua faktor yaitu konsentrasi minyak wijen (0% dan 0,5%) dan lama penyimpanan (0,12,24,36,48) dengan 3 kali pengulangan. Daya awet bakso ikan dilihat berdasarkan uji organoleptik, kadar air, pH, nilai TBA dan kekuatan gel. Data parametrik dianalisis dengan ANOVA, sedangkan data non-parametrik menggunakan uji Kruskal wallis. Hasil pada bakso ikan lele dengan penambahan minyak wijen 0,5% pada edible coating dapat diterima hingga penyimpanan selama 36 jam dengan nilai organoleptik 7,04< <7,70, nilai kadar air 65,91%±0,82, nilai pH 6,25±0,02, nilai TBA 0,52±0,01 mg malonaldehid/kg dan nilai kekuatan gel 1937,60±118,74 gf. Penambahan minyak wijen sebagai antioksidan pada edible coating bakso ikan lele hanya mampu memperpanjang umur simpan bakso selama penyimpanan 36 jam dibandingkan dengan kontrol.
PENGARUH PENAMBAHAN JENIS GULA YANG BERBEDA TERHADAP KUALITAS PETIS DARI CAIRAN PEMINDANGAN IKAN TONGKOL (Euthynnus affinis)
Authors: Ramandhani Sasti Nuriza , Agustini Tri Winarni , Suharto Slamet 
Published: May 2023

ABSTRAKPetis merupakan salah satu jenis bumbu masakan yang diperoleh dari hasil pengentalan air rebusan ikan yang dipanaskan selama waktu tertentu hingga kandungan air berkurang. Petis ikan yang dihasilkan dari cairan pemindangan cenderung memiliki rasa asin karena kadar garam tinggi. Penambahan jenis gula berbeda dalam proses pembuatan petis diharapkan dapat mengurangi rasa asin pada petis dan memenuhi kriteria organoleptik yang disukai konsumen. Tujuan penelitian ini mengetahui pengaruh jenis gula terhadap karakteristik kimia, hedonik petis dan memperoleh informasi jenis gula terbaik dalam pembuatan petis serta disukai oleh konsumen. Metode penelitian yang digunakan adalah experimental laboratories menggunakan Rancangan Acak Lengkap (RAL) dengan 3 perlakuan (gula pasir, gula cair glukosa, dan gula cair fruktosa) dengan 3 kali pengulangan. Parameter uji yang dilakukan yaitu kadar air, kadar protein, kadar garam, asam glutamat, aw dan sensori. Data parametrik (kadar air, kadar protein, kadar garam, asam glutamat dan aw) dianalisa menggunakan uji ANOVA dan uji lanjut BNJ, sedangkan data nonparametrik (hedonik) menggunakan uji Kruskal Wallis dan uji lanjut Mann Whitney. Hasil uji hedonik menunjukkan bahwa petis dengan penambahan gula cair fruktosa memiliki nilai tertinggi yaitu 7,05<µ<7,44. Penambahan jenis gula berbeda memberikan pengaruh nyata (P≤0,05) terhadap kadar air, kadar asam glutamat serta hedonik (rasa dan tekstur). Perlakuan terbaik yaitu pada penambahan gula cair fruktosa dengan nilai kadar air 24,59%; kadar protein 8,74%; kadar garam 3,89%; kadar asam glutamat 3,52%; nilai aw 0,5, nilai hedonik kenampakan (6,8), aroma (6,83), rasa (7,6) dan tekstur (7,76).
The effects of resistance training to near failure on strength, hypertrophy, and motor unit adaptations in previously trained adults
Authors: Ruple Bradley A. , Plotkin Daniel L. , Smith Morgan A. , Godwin Joshua S. , Sexton Casey L. , McIntosh Mason C. , Kontos Nicholas J. , Beausejour Jonathan P. , Pagan Jason I. , Rodriguez Juan P. , Sheldon Daniel , Knowles Kevan S. , Libardi Cleiton A. , Young Kaelin C. , Stock Matt S. , Roberts Michael D. 
Published: May 2023

AbstractLimited research exists examining how resistance training to failure affects applied outcomes and single motor unit characteristics in previously trained individuals. Herein, resistance‐trained adults (24 ± 3 years old, self‐reported resistance training experience was 6 ± 4 years, 11 men and 8 women) were randomly assigned to either a low‐repetitions‐in‐reserve (RIR; i.e., training near failure, n = 10) or high‐RIR (i.e., not training near failure, n = 9) group. All participants implemented progressive overload during 5 weeks where low‐RIR performed squat, bench press, and deadlift twice weekly and were instructed to end each training set with 0–1 RIR. high‐RIR performed identical training except for being instructed to maintain 4–6 RIR after each set. During week 6, participants performed a reduced volume‐load. The following were assessed prior to and following the intervention: (i) vastus lateralis (VL) muscle cross‐sectional area (mCSA) at multiple sites; (ii) squat, bench press, and deadlift one‐repetition maximums (1RMs); and (iii) maximal isometric knee extensor torque and VL motor unit firing rates during an 80% maximal voluntary contraction. Although RIR was lower in the low‐ versus high‐RIR group during the intervention (p < 0.001), total training volume did not significantly differ between groups (p = 0.222). There were main effects of time for squat, bench press, and deadlift 1RMs (all p‐values < 0.05), but no significant condition × time interactions existed for these or proximal/middle/distal VL mCSA data. There were significant interactions for the slope and y‐intercept of the motor unit mean firing rate versus recruitment threshold relationship. Post hoc analyses indicated low‐RIR group slope values decreased and y‐intercept values increased after training suggesting low‐RIR training increased lower‐threshold motor unit firing rates. This study provides insight into how resistance training in proximity to failure affects strength, hypertrophy, and single motor unit characteristics, and may inform those who aim to program for resistance‐trained individuals.
On a new class of two-variable functional equations on semigroups with involutions
Authors: EL-Fassi Iz-iddine 
Published: May 2023

Abstract
Let 𝑆 be a commutative semigroup, 𝐾 a quadratically closed commutative field of characteristic different from 2, 𝐺 a 2-cancellative abelian group and 𝐻 an abelian group uniquely divisible by 2.
The goal of this paper is to find the general non-zero solution

f
:

S
2

→
K

f\colon S^{2}\to K

of the d’Alembert type equation

f
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(

x
+
y

,

z
+
w

)

+

f
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(

x
+

σ
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(
y
)

,

z
+

τ
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(
w
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)

=

2
⁢
f
⁢

(
x
,
z
)

⁢
f
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(
y
,
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)

,
x
,
y
,
z

,

w
∈
S

,

f(x+y,z+w)+f(x+\sigma(y),z+\tau(w))=2f(x,z)f(y,w),\quad x,y,z,w\in S,

the general non-zero solution

f
:

S
2

→
G

f\colon S^{2}\to G

of the Jensen type equation

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(

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+
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,

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+

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=

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(
x
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)

,
x
,
y
,
z

,

w
∈
S

,

f(x+y,z+w)+f(x+\sigma(y),z+\tau(w))=2f(x,z),\quad x,y,z,w\in S,

the general non-zero solution

f
:

S
2

→
H

f\colon S^{2}\to H

of the quadratic type equation

f
⁢

(

x
+
y

,

z
+
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)

+

f
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(

x
+

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=

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+

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(
y
,
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)

,
x
,
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,
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,

w
∈
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,

f(x+y,z+w)+f(x+\sigma(y),z+\tau(w))=2f(x,z)+2f(y,w),\quad x,y,z,w\in S,

where

σ
,
τ

:

S
→
S

\sigma,\tau\colon S\to S

are two involutions.
Optimization of ultra-high pressure-assisted extraction of total phenols from Eucommia ulmoides leaves by response surface methodology
Authors: Ren Xiao-yan , Jin Xue-yuan , Zong Wei 
Published: May 2023

Abstract
The ultra-high pressure-assisted extraction (UHPE) of total phenols from Eucommia ulmoides leaves (TPEU) was optimized and its antioxidant activity on Eucommia ulmoides seed oil was studied. The effects of UHPE pressure, UHPE time, and ethanol concentration on the extraction yield of TPEU were examined by response surface methodology. In addition, TPEU was added to Eucommia ulmoides seed oil, and the effects of TPEU on the antioxidant activity (acid value, peroxide value) of Eucommia ulmoides seed oil during storage were studied. The optimal UHPE conditions were as follows: UHPE pressure, 406 MPa; UHPE time, 8.3 min; and ethanol concentration, 60.2%. Under these UHPE conditions, the yield of TPEU was 7.58%. TPEU had a good antioxidant effect when the TPEU content was 0.06%. The antioxidant effect of TPEU was lower than that of BHA. Both TPEU and BHA have a synergistic effect.
To drop or not to drop? Predicting the omission of the infinitival marker in a Swedish future construction
Authors: Berdicevskis Aleksandrs , Coussé Evie , Koplenig Alexander , Adesam Yvonne 
Published: May 2023

AbstractWe investigate the optional omission of the infinitival marker in a Swedish future tense construction. During the last two decades the frequency of omission has been rapidly increasing, and this process has received considerable attention in the literature. We test whether the knowledge which has been accumulated can yield accurate predictions of language variation and change. We extracted all occurrences of the construction from a very large collection of corpora. The dataset was automatically annotated with language-internal predictors which have previously been shown or hypothesized to affect the variation. We trained several models in order to make two kinds of predictions: whether the marker will be omitted in a specific utterance and how large the proportion of omissions will be for a given time period. For most of the approaches we tried, we were not able to achieve a better-than-baseline performance. The only exception was predicting the proportion of omissions using autoregressive integrated moving average models for one-step-ahead forecast, and in this case time was the only predictor that mattered. Our data suggest that most of the language-internal predictors do have some effect on the variation, but the effect is not strong enough to yield reliable predictions.
Stability analysis of an SIR model with alert class modified saturated incidence rate and Holling functional type-II treatment
Authors: Sharma Shivram , Sharma Praveen Kumar 
Published: May 2023

Abstract
This study discusses an SIR epidemic model with modified saturated incidence rates and Holling functional type-II therapy. In this study, we take the new alert compartment (A) in the SIR compartment model. Consider the modified non-linear incidence rate from the susceptible to the infected class and the second non-linear incidence rate from the alert to the infected class. Further, we investigate the elementary reproduction number, the equilibrium points of the model, and their stability. We apply manifold theory to discuss bifurcations of the disease-free equilibrium point. This study shows that the infected population decreases with the Holling functional type II treatment rate. It also shows that the number of infected people decreases when the psychological rate increases and the contact rate decreases.
Rethinking Agency in the European Debate about Virginity Certificates: Gender, Biopolitics, and the Construction of the Other
Authors: Tack Saartje 
Published: May 2023

Abstract
Several European countries have taken measures to discourage or ban physicians from issuing virginity certificates to migrant women, with the stated aim of protecting these women from oppression. Arguments against the practice are centred around questions of medical ethics, gender inequality, and autonomy. What underpins these arguments is an evaluation of whether women have a choice in matters related to their sexuality. This article shows that the reasons provided for why virginity certificates should not be issued can similarly be applied to the prescription of erectile dysfunction medication, yet the latter practice remains largely unquestioned. It argues that the discrepancy in approaches to both practices points to an a priori understanding of migrant women as non-agentic, grounded in racial gendered norms, and that agency is mobilised as a biopolitical tool to Other migrant women and communities. Current approaches towards virginity certificates thus replicate the oppression of the migrant women they (cl)aim to liberate.