bluuebunny/crossref_metadata_2025_split huggingface dataset:
Causal Model of Health Literacy in Thai Older Adults with Knee Osteoarthritis
Authors: Porntip Pa-in  , Tipaporn Wonghongkul  , Sirirat Panuthai  , Totsaporn Khampolsiri  , Rojanee Chintanawat  
Published: August 2023

Knee osteoarthritis is the most common form of arthritis causing disability among older adults. Proper self-care is vital and achievable with health literacy. Thai older adults with knee osteoarthritis have been found to have inadequate health literacy, and poor selfcare behaviors for this condition. The purpose of this descriptive cross-sectional study was to test a causal model of health literacy in Thai older adults with knee osteoarthritis, depicting relationships among provider-patient communication, patient engagement, cognitive function, knowledge of knee osteoarthritis, Internet use, social support, social participation, and health literacy. Participants comprised 318 older adults with knee osteoarthritis, selected using multi-stage random sampling from nine community hospitals in a northern Thai province. Data were collected using a demographic data form, the European Health Literacy Survey Questionnaire, the Provider-patient Communication Scale, the Patient Health Engagement Scale, the Montreal Cognitive Assessment-Basic, the Arthritis Knowledge Scale, the Internet Use Questionnaire, the Social Support Questionnaire, and the Community Participation of the Elderly Questionnaire. Data were analyzed using descriptive statistics, Pearson’s product moment correlation, and structural equation modeling. The final model fitted with empirical data and explained 36% of the variance in health literacy with Internet use as the strongest predictor directly affecting health literacy. Internet use and social participation had positive direct and indirect effects on health literacy via cognitive function. Cognitive function and social support positively directly affected health literacy. Patient engagement negatively affected health literacy indirectly via Internet use. Knowledge of knee osteoarthritis and provider-patient communication did not affect health literacy directly or indirectly. In conclusion, nurses should design interventions to promote health literacy of this population by highlighting Internet use, social participation, cognitive function, social support, and patient engagement, with testing in clinical practice.
Análise da segurança alimentar e nutricional de agricultores orgânicos na Zona da Mata Setentrional pernambucana
Authors: De Freitas Rubenice Maria , Marjotta-Maistro Marta Cristina , Montebello Adriana Estela Sanjuan , Figueiredo Marcos Antonio Bezerra 
Published: August 2023

A alimentação é um fator necessário para a vida humana, sendo um direito dos cidadãos. No entanto, nem todos tem exercido esse direito, a fome a cada dia assombra muitas famílias, principalmente no período de pandemia da Covid-19. Existe um outro fator importante a ser considerado no que se refere a saciar a fome da humanidade, é a produção de alimentos saudáveis disponíveis para população. Diante disto, esta pesquisa tem por finalidade avaliar o índice da segurança alimentar e nutricional dos agricultores orgânicos da Zona da Mata Setentrional. A metodologia utilizada foi a Escala Brasileira de Insegurança Alimentar (EBIA), e aplicou-se um formulário com 14 perguntas, de acordo com a idade da composição familiar. Neste formulário são feitas 8 perguntas para famílias que só tem indivíduos maiores de 18 anos e 14 para as famílias com indivíduos menores de 18 anos, pois as perguntas sucessivas a questão 8 são direcionadas aos indivíduos menores de 18 anos, o que não se aplica aos grupos familiares que não tenham indivíduos com esta faixa etária. A coleta dos dados é feita da seguinte forma: duas etapas com intervalo de 30 dias de uma para outra. Como principais resultados identificou-se índices de insegurança alimentar leve e moderado, sendo o índice de segurança alimentar maior em ambas as entrevistas. A pesquisa mostra que mesmo diante da apresentação de níveis de insegurança alimentar do grupo, o envolvimento com a agricultura orgânica e os espaços de comercialização contribuíram para a promoção da segurança alimentar deste público.
Morphological Screening and Genetic Variability Analysis in Rice (Oryza sativa L.) Genotypes for Salinity Tolerance
Authors: Singh Anoushka , Dwivedi D. K. , Khan N. A. , Dixit Saurabh , Antardani Soumya , Ritendra  , Pooja  , Kumari Preeti 
Published: August 2023

This experiment was conducted to estimate the genetic variability and correlation between yield and yield related characters of 22 rice genotypes at Genetics and Plant Breeding Farm of Acharya Narendra Deva University of Agriculture and Technology, Kumarganj, Ayodhya. This experiment was laid in Randomized Block Design (RBD) during Kharif season of 2022-23 under saline condition. Analysis of variance shows significant differences among 22 rice genotypes under saline condition. GCV (Genotypic coefficient of variation) and PCV (Phenotypic coefficient of variation) estimates were higher for traits such as panicle bearing tillers/plant, harvest index and biological yield indicating selection of rice genotypes for yield and component traits under saline condition. High heritability coupled with higher genetic advance was observed for traits like grains/panicle, days to 50% flowering, spikelets number and plant height. Grain yield/plant was strongly related to harvest index, panicle bearing tiller /plant and biological yield per plant. Path coefficient analysis showed that harvest index followed by biological yield /plant and panicle bearing tillers/plant has positive direct effect on grain yield/plant.
Advancements in Breeding Strategies for Enhancing Wilt and Root Rot Resistance in Castor (Ricinus communis L.): A Comprehensive Review
Authors: Kashyap Abhishek , Delvadiya I. R. 
Published: August 2023

Castor (Ricinus communis L.) is an economically important oilseed crop cultivated worldwide for its versatile uses in various industries. However, the cultivation of castor is challenged by wilt and root rot diseases caused by fungal pathogens, leading to significant yield losses. Enhancing wilt and root rot resistance in castor is crucial for sustainable and productive cultivation. This review explores advancements in breeding strategies for enhancing resistance against these diseases through various approaches along with introduction to castor cultivation and the challenges posed by wilt and root rot diseases in castor. It emphasizes the importance of breeding for disease resistance and discusses the significance of genetic diversity in castor germplasm. Traditional breeding approaches including phenotypic selection, recurrent selection, hybridization, mutation breeding and polyploidy induction are examined for their effectiveness in introducing and accumulating resistance genes and traits. Biotechnological approaches such as marker-assisted selection (MAS), genetic transformation and RNA interference (RNAi) are highlighted as powerful tools for targeted selection and manipulation of specific genes associated with disease resistance. The utilization of physiological and biochemical approaches including understanding host-pathogen interactions, elicitor-induced defense responses and metabolic engineering are discussed for enhancing resistance mechanisms in castor. These advancements offer promising avenues for accelerating the development of wilt and root rot-resistant castor varieties.
Influence of Organic Manures and Inorganic Fertilizers on Growth, Yield and Quality of Turnip (Brassica rapa L.)
Authors: Sneha M. S. , Deepanshu  , Noushad Reenu 
Published: August 2023

An experiment entitled the Influence of organic manures and Inorganic fertilizers on growth, yield and quality of turnip (Brassica rapa L.) cv. Purple Top white globe was conducted at Department of Horticulture, Naini Agriculture Institute, SHUATS, Prayagraj during, Rabi season of 2022. The experiment was laid out in Randomized Block Design with fifteen treatments combination and three replications in which Farmyard manure (FYM), Poultry manure, Vermicompost were used. Among all the treatments, T11 (80% Nitrogen + 10% FYM + 10% Vermicompost) showed significant result in terms of plant height (29.13cm), maximum number of leaves/plant (13.81), higher Shoot weight (166.81g), maximum Root diameter (7.40 cm), average root length (9.04 cm), average fresh weight/ plant (162.59 g), average root yield (55.77 q/ha), ascorbic acid (36.19 mg), TSS (6.08o Brix).
Effect of Boron and Lime on Boron Transformation in a Fluvaquentic Humaquepts Soil Concerning Uptake and Yield of Green Gram
Authors: Das Hiren , Devi N. Surbala , Venu Nakeertha , Sarkar Animesh , Tamalam Akhil Dev , Devi Laishram Nikita 
Published: August 2023

Understanding different fractions and availability of boron (B) is essential while studying the response of crops towards B. Fractionation provides information about the chemistry of B and quantifies its bioavailability. Therefore, a pot experiment was performed during the 2019 pre-kharif season in acid soil to study soil B fractions and response of green gram (Vigna radiata L.) to B application. Lime is applied to such soils with the primary objective of increasing the productivity of crops by enhancing the availability of native and applied plant nutrients. On the contrary, availability of B in soil was increase due to liming. The treatments comprised of five levels of soil applied B (0, 0.5, 1.0, 1.5 and 2.0 mg B kg−1) and two levels of lime, lime and no lime was used. The experiment was laid out in factorial randomized block design (FRBD) with three replications. The soil and pant growth parameters were recorded at a regular interval of 15 days after sowing, and at harvest. All the result revealed that the changes in different fractions of B (viz., readily soluble, specifically adsorbed, oxide bound, organically bound, residual and total B), its plant uptake and yield of green gram are significantly affected by the application of B and lime. All the fractions contribute towards plant available boron form. Inter conversion between B fractions was also observed. The application of B and lime significantly influenced different B pools, boron uptake and yield of green gram.
Sweet Potato (Ipomea batatas L.): A New Alternative Host of Two Phytoplasmas Associated with Coconut Lethal Yellowing Disease in Côte d’Ivoire
Authors: Ouattara Bognan Winnie Miyasi , Kra Kouamé Daniel , Kouakou Yadom Yao François Regis , Toualy Marie Noel Yeyeh , Diallo Hortense Atta 
Published: August 2023

Aims: Coconut Lethal Yellowing Disease has been threatening coconut plantations in Côte d'Ivoire for ten years and has destroyed more than 400 ha. The destruction of the coconut palm leads to phytoplasmas conservation on other plants grown in association or near of the disease outbreaks. Thus, the search for possible alternative host species was conducted.
Methodology: Surveys were carried out in infected coconut plantations, in order to describe symptoms associated with phytoplasma infections and to collect leaf samples of plant species other than coconut. Symptomatic and non-symptomatic leaves of sweet potato (Ipomea batatas L.) were collected for DNA extraction. The extracted DNA was subjected to molecular characterization.
Results: Mosaic and leaf reduction symptoms were observed on sweet potato leaves. From these samples, two phytoplasma strains were associated. Molecular analysis showed the presence of the endemic phytoplasma strain belonging to the 16SrXXII-B subgroup ʺCandidatus Phytoplasma palmicolaʺ. Sequencing and phylogenetic analysis also revealed the presence of a new phytoplasma strain, sharing 99% similarity with 16SrIV group strains ʺCandidatus Phytoplasma palmaeʺ.
Conclusion: The detection of these strains confirms sweet potato for the very first time, as an alternative host for coconut lethal yellowing phytoplasmas in Côte d'Ivoire.
Towards Incorporation in Larger Architectures: A Polymeric Halogen Bond‐Based Iridium Sensor
Authors: Kampes Robin , Kleine Alexander , Langstein Silas , Zechel Stefan , Hager Martin D. , Schubert Ulrich S. 
Published: August 2023

AbstractThis study reports the synthesis and characterization of a "click‐able" iridium(III) complex as halogen bond‐based anion sensor. The functionalization is exemplarily demonstrated by the attachment of poly(ethylene glycol) azide via a "copper‐click"‐reaction. Subsequently, the polymeric XB donor complex is characterized in depth with 1H NMR spectroscopy, size exclusion chromatography, and MALDI‐ToF‐MS. Moreover, the anion binding capabilities are demonstrated with emission titrations revealing strong anion complexation. These findings emphasize the great potential of this approach to tune the complex's properties or include other functions such as cation complexation sites to exploit cooperative effects by using polymeric substituents on the iridium complex.
Synthesis of Self‐healing and Light‐, Thermal‐, and Humidity‐induced Deformative Polyurethane Actuator
Authors: Dong Chen , Yue Xiaolei , Zhang Yaodu , Wang Yucheng , Ren Zhi‐Hui , Guan Zheng‐Hui 
Published: August 2023

AbstractIntelligent actuating materials have drawn enormous attention because of their potential applications in soft robots, smart sensors, bionics, etc. Aiming to integrate light, thermal, and humidity stimuli deformations and self‐healing function into a single polymer, a smart actuating polyurethane material CPPU‐50 is designed and successfully synthesized through co‐polymerization of azobenzene‐containing Azo‐C12, polyethylene glycol 200 (PEG200), and 4,4'‐diphenylmethane diisocyanate (MDI) at a ratio of 1:1:2. The obtained polyurethane CPPU‐50 exhibits good photoinduced bending, thermal responsive shape memory effect, humidity triggered deflections and self‐healing properties. Furthermore, an actuator combining light and thermal stimuli is created and the self‐healing CPPU‐50 film can withstand the object of 1800 times without tearing. This work can pave a way for further development of long‐lived multi‐stimuli‐responsive actuating devices and intelligent materials.
People: The Starting Point and the Destination of Literary Criticism
Authors: Hu Yamin 
Published: August 2023

AbstractThe People is a primary concept of the Chinese form and is simultaneously the starting point and the destination of it. Inheriting historical materialism’s discourse, the concept of people in the Chinese form acquires a novel quality. “The people become a revolutionary aggregation of classes with broad common interests and an association based on but also transcend class,” and the people are all millions of real individuals. The people are the creators of history. Instead of regarding the masses or citizens mainly as the objects of salvation as Western Marxists, the Chinese form adheres to the subjectivity of the people and recognizes the people as the masters of the society. “The priority of people” is the prominent feature of the Chinese form. The relationship between literature and the people constitutes the cornerstone of the Chinese form. The Chinese form concludes and presents creative theoretical views on problems such as whom literature should serve and how to serve, and such clear and systematic inquiry is unprecedented in the history of Marxist literary criticism studies. Today, the relationship between literature and the people needs reconsideration and expansion. Interacting and mutual shaping with each other, the people and literature/art will open a new era.
The Political Dimension of Literary Criticism
Authors: Hu Yamin 
Published: August 2023

AbstractThis chapter sums up a threefold meaning of the concept of politics for classical Marxist writers which are intrinsically unified in historical materialism: (i) politics as a component of the superstructure in the social structure; (ii) politics as class interests and class struggle; (iii) politics as human emancipation. Since the twentieth century, the relationship between literature and politics has undergone a process of politicization (or over-politicization), depoliticization, and eventually repoliticization. In our new historical context, the connotation and extension of politics are changing from class politics to people’s politics, from macro-politics to micro-politics, and from explicit politics to implicit politics. The repoliticization (or the turning-back) and transformation of politics urge the Chinese form to re-examine the complex relationship and transformation between aesthetics and politics from theoretical and practical ways. On the relationship between politics and aesthetics, the Chinese form is supposed to deterritorialize the boundaries extrinsic or intrinsic in current literary criticism by envisioning that the criticism and its emancipation function are gestated precisely in aesthetics.
Marxist Literary Criticism in the Hi-Tech Era
Authors: Hu Yamin 
Published: August 2023

AbstractWith historical materialistic view of science and technology as the first productive force, the revolutionary influence of technology on literature and ideological construction function of science and technology are elaborated. For literary creation, high technology dismantles the content, structure, and expression of traditional literary texts, as well as to provide new opportunities for literature. It updates our understanding of the world, brings novel aesthetic experiences and imaginations, and urges innovative literary styles and structures, which leads to a restructuring of literary concepts. With its own unique attributes and advantages, contemporary literary creation should remain reflective and transcendent toward science and technology to facilitate human beings to achieve poetic dwelling in an age of high technology. As for reading, a digital era of “Internet reading” is coming followed by the era of “text reading” and “picture reading.” The convenience of “Internet reading” changes readers’ perception and thinking habits. The reshaping of the reading subject and the emphasis on “the reader’s autonomy” is the most fundamental strategy to deal with the shortcomings of the “Internet reading era” such as fragmentation of information, weakening of deep thinking and forgetting. The “Internet reading era” calls for readers with competence to choose, critical ability, and productive capacity.
Conclusion
Authors: Hu Yamin 
Published: August 2023

AbstractThe Chinese form involves a process of continuous discovery and construction. Combing the study of key words and differences, the book inquires and presents the theoretical characteristics of the Chinese form by starting with concrete concepts and issues. The study of differences as the book adheres to does not imply confrontation or conflicts; instead, it provides the basis for dialogue with literary criticism all over the world precisely on the basis of recognizing and embracing differences. The Chinese form is guided by the concept of “Learning is not limited to the West or the East” when assimilating and incorporating different systems of discourses. The core of the study of differences is to discover and generate theoretical discourses with distinct local features and to produce a theory of Chinese Marxist literary criticism that accommodates deep emotions regarding the nation and has universal, global relevance as well. The core concepts and contemporary issues throughout the book all point to one end—full emancipation of human beings, where lies the universality of the Chinese form among its particularities.
Multi-omics profiling of CSF from spinal muscular atrophy type 3 patients after nusinersen treatment: a 2-year follow-up multicenter retrospective study
Authors: Faravelli Irene , Gagliardi Delia , Abati Elena , Meneri Megi , Ongaro Jessica , Magri Francesca , Parente Valeria , Petrozzi Lucia , Ricci Giulia , Farè Fiorenza , Garrone Giulia , Fontana Manuela , Caruso Donatella , Siciliano Gabriele , Comi Giacomo Pietro , Govoni Alessandra , Corti Stefania , Ottoboni Linda 
Published: August 2023

AbstractSpinal muscular atrophy (SMA) is a neurodegenerative disorder caused by mutations in theSMN1gene resulting in reduced levels of the SMN protein. Nusinersen, the first antisense oligonucleotide (ASO) approved for SMA treatment, binds to theSMN2gene, paralogue toSMN1, and mediates the translation of a functional SMN protein. Here, we used longitudinal high-resolution mass spectrometry (MS) to assess both global proteome and metabolome in cerebrospinal fluid (CSF) from ten SMA type 3 patients, with the aim of identifying novel readouts of pharmacodynamic/response to treatment and predictive markers of treatment response. Patients had a median age of 33.5 [29.5; 38.25] years, and 80% of them were ambulant at time of the enrolment, with a median HFMSE score of 37.5 [25.75; 50.75]. Untargeted CSF proteome and metabolome were measured using high-resolution MS (nLC-HRMS) on CSF samples obtained before treatment (T0) and after 2 years of follow-up (T22). A total of 26 proteins were found to be differentially expressed between T0 and T22 upon VSN normalization and LIMMA differential analysis, accounting for paired replica. Notably, key markers of the insulin-growth factor signaling pathway were upregulated after treatment together with selective modulation of key transcription regulators. Using CombiROC multimarker signature analysis, we suggest that detecting a reduction of SEMA6A and an increase of COL1A2 and GRIA4 might reflect therapeutic efficacy of nusinersen. Longitudinal metabolome profiling, analyzed with pairedt-Test, showed a significant shift for some aminoacid utilization induced by treatment, whereas other metabolites were largely unchanged. Together, these data suggest perturbation upon nusinersen treatment still sustained after 22 months of follow-up and confirm the utility of CSF multi-omic profiling as pharmacodynamic biomarker for SMA type 3. Nonetheless, validation studies are needed to confirm this evidence in a larger sample size and to further dissect combined markers of response to treatment.
Synergistic effects of hormones on structural and functional maturation of cardiomyocytes and implications for heart regeneration
Authors: Galow Anne-Marie , Brenmoehl Julia , Hoeflich Andreas 
Published: August 2023

AbstractThe limited endogenous regenerative capacity of the human heart renders cardiovascular diseases a major health threat, thus motivating intense research on in vitro heart cell generation and cell replacement therapies. However, so far, in vitro-generated cardiomyocytes share a rather fetal phenotype, limiting their utility for drug testing and cell-based heart repair. Various strategies to foster cellular maturation provide some success, but fully matured cardiomyocytes are still to be achieved. Today, several hormones are recognized for their effects on cardiomyocyte proliferation, differentiation, and function. Here, we will discuss how the endocrine system impacts cardiomyocyte maturation. After detailing which features characterize a mature phenotype, we will contemplate hormones most promising to induce such a phenotype, the routes of their action, and experimental evidence for their significance in this process. Due to their pleiotropic effects, hormones might be not only valuable to improve in vitro heart cell generation but also beneficial for in vivo heart regeneration. Accordingly, we will also contemplate how the presented hormones might be exploited for hormone-based regenerative therapies.
Graphical abstract