bluuebunny/crossref_metadata_2025_split huggingface dataset:
DİYALİZ TEDAVİSİ MALİYETLERİNİN KARŞILAŞTIRILMASI
Authors: BANKUR Mutlu , AĞIRBAŞ İsmail 
Published: July 2023

Sağlık insanlık için diğer bütün göstergelerden daha öncelikli öneme sahiptir. Hayatta olmaktan sonra yaşamın gereklerini yerine getirebilmek için öncelikli ve olmazsa olmaz olgu sağlıktır. Günümüzde insanların yitirmiş oldukları sağlıklarına kavuşabilmek için yaptıkları sağlık harcamaları sürekli bir artış göstermektedir. Kronik hastalıklar genellikle yavaş ilerleyen, düzenli ve sürekli tedavi, bakım ve izlem gerektiren uzun dönem sağlık sorunlarıdır.
Kronik Böbrek Hastalığı Türkiye’de ve dünyada sürekli artış gösteren önemli bir sağlık sorunudur. Hastalığın artan sıklığı, yaşam kalitesini önemli bir seviyede etkilemesi, farkındalığının toplum tarafından oldukça düşük olması ve tedavisinin son derece yüksek maliyetler içermesi nedeniyle toplumsal yükü büyük olan bir hastalıktır.
Bu çalışmada; Türkiye’de son dönem böbrek yetmezliğinde uygulanan renal replasman tedavisi yöntemlerinden merkez hemodiyalizi, ev hemodiyalizi ve periton diyalizinin doğrudan maliyetlerinin belirlenerek karşılaştırılması amaçlanmaktadır. Bu kapsamda geri ödeme kurumu perspektifi esas alınmış olup, Türkiye’de Sosyal Güvenlik Kurumunca diyaliz hastalarına yapılan tüm harcamalar ortaya konulmuştur. Çalışma verilerinin belirli bir dönemi kapsaması nedeniyle bu çalışma kesitsel türde bir çalışmadır.
Verilerin analiz edilmesinde farklı istatistiksel yöntemlerden faydalanılmış olup, öncelikle tanımlayıcı bulgular frekans analizi ve çeşitli grafikler aracılığıyla sunulmuştur.
Son dönme böbrek yetmezliği tedavisinde kullanılan diyailz tedavilerinin birbirlerine üstünlükleri noktasında literatürdeki çalışmalarda bir kesinlik bulunmamaktadır. Ancak çalışmada ev hemodiyalizi kişi başı ortalama maliyetinin diğer diyaliz türlerine göre düşük olarak saptanması ve aynı zamanda düşük hastaneye yatış sayıları nedeniyle tercih edilmelidir. Bu nedenle Sosyal Güvenlik Kurumunun bu uygulamanın yaygınlaştırılması için Sağlık Uygulama Tebliğinde teşvik edici düzenlemeler yapması uygun olabilir.
Behavior of household water consumption in Mexico during the COVID-19 pandemic
Authors: Revollo-Fernández Daniel Alfredo , Rodríguez-Tapia Lilia , Mazari-Hiriart Marisa , Espinosa-García Ana Cecilia 
Published: July 2023

Abstract

Populations have changed their habits and consumption as a result of COVID-19. In the case of Mexico City, this situation has possibly led households to purchase more products such as bottled water and to consume the same amount or less tap water. This behavior was confirmed by analyzing tap water consumption data before and during the arrival of COVID-19 using Pearson chi-square, and by conducting a survey of bottled and tap water consumption and analyzing that data with a bivariate econometric model. It was found to be related to the perception of poor-quality service. Consequently, tap water consumption will not always increase when health emergencies such as COVID-19 occur, but rather, this will depend on other environmental variables. Therefore, public water policies should be aimed at offering and ensuring a continuous supply of good quality water, as well as providing clear and objective information to prevent this type of behavior
Technical and environmental aspects of solar photo-voltaic water pumping systems: a comprehensive survey
Authors: Gunasekaran V. , Chakraborty Suprava 
Published: July 2023

Abstract

Several sectors including agriculture and farming rely on renewable source-based water pumping due to recurrent hikes in fossil fuel prices and contaminant environment. In recent decades, a solar photovoltaic-based water pumping system (SPVWPS) has been a more popularly chosen technique for its feasibility and economic solution to the end-users. The initial cost, efficiency, orientation, auxiliary storage, head, and payback period are the technical issues, whereas transportation, lack of skilled people, theft, vandalism community, and politics are the social challenges that may prevent the solar pumps from being widely adopted. However, more subsidies, training, tax breaks, and remote monitoring can make this technology more accessible. Also, this article emphasizes various parameters affecting system performance, such as the suitable selection of panels, power conditioning units, motors, pumps, the payback period of the energy, and cost. Moreover, this article covers the technical and environmental facets of the SPVWPS, which helps researchers, policymakers, manufacturers, and end-users to design and choose a suitable pumping system. Major findings are stand-alone SPVWPS is highly recommended in areas with a maximum of 50 m dynamic head and a minimum of 2,000 m from local grid power. Moreover, along with the 25-year life span of the 25-kW SPVWPS could generate 150 MWh/year and reduce about 86,500 kg of CO2 emissions.
Methodological analysis of the incompatible EBITDA disclosed by companies listed on B3: identification of divergent variables in the conciliations
Authors: Kistner Shaiane Pisa , Platt Neto Orion Augusto 
Published: July 2023

Purpose: To identify the variables responsible for the methodological divergences causing incompatibilities in the EBITDA disclosed by the companies listed on B3, related to errors in data collection and undue changes in the formula by the conciliation issuers.
Methodology: Application of descriptive statistics on a sample of 35 entities that disclosed the incompatible EBITDA for 2018, observing the behavior of the indicator's variables in the years 2018, 2019 and 2020.
Results: The most common cause of incompatibilities in EBITDA occurred when collecting data from the financial statements. The variable that most impacted erroneously calculated values was related to Depreciation, Depletion, and Amortization. It is concluded that, even with the standardization of the disclosure of EBITDA by the Securities and Exchange Commission of Brazil since 2012, errors in the calculation of this indicator are still common, which reinforces the need for practical studies that verify the conformity of these companies' non-GAAP disclosures.
Contributions of the Study: Considering that non-GAAP performance measures, such as EBITDA, are disseminated worldwide among investors and analysts to analyze companies results, such measures are at risk of error and manipulation by the issuers' managers. In this sense, the study contributed to the practical sphere because it demonstrated which errors companies effectively made when calculating and demonstrating their EBITDA conciliations. In addition, it bridges an academic gap concerning the methodology for calculating EBITDA, since even with the growing literature related to non-GAAP disclosures, the method of calculating the indicator has received low attention.
Evolving Advances in the Cosmetic use of Probiotics and Postbiotics:
Health, Regulatory and Marketing Aspects
Authors: Arora Rashmi , Kaur Rajwinder , Babbar Ritchu , Dhingra Smriti , Dhingra Ashwani K. , Grewal Ajmer S. 
Published: July 2023

Abstract:
Ongoing development in cosmetics is increasingly making use of probiotics, which are
defined as “live microorganisms with health-enhancing properties mediated through ingestion or
topical application to the host”. The observation that several bacterial strains augment normal processes
of healthy tissue maintenance, particularly for the skin, has opened up new avenues for the
use of bacterial strains in cosmetics. A principal feature of such “cosmeceuticals” is an application
of increasing insight into the biochemical nature of the skin’s normal microbial flora, also called
its microbiome. The opportunity of manipulating the skin microbiome to address various skin
disorders has revealed novel routes for treatment. The skin microbiome manipulation approaches
to address various skin disorders include skin microbiome transplantation, skin bacteriotherapy,
and prebiotic stimulation. Research in this field has revealed that medical outcome-targeted manipulation
of skin microbiome bacterial strain makeup may significantly increase skin health and
appearance. Commercial availability of probiotic skincare products is rapidly expanding worldwide
due to satisfactory laboratory results and public perception of probiotics as being intrinsically
more wholesome than other bioactive substances, such as synthetics. Major outcomes of probiotic
use include a significant reduction in skin wrinkling, acne and other conditions adversely affecting
skin appearance and healthy function. Moreover, probiotics may additionally promote normal skin
hydration, resulting in a vibrant and lustrous appearance. Nevertheless, significant technical challenges
remain for the full optimization of probiotics in cosmetic products. This article summarizes
the evolving nature of this field and explores current probiotic research initiatives, along with regulatory
aspects and significant challenges in the manufacturing of cosmetics in the context of market
expansion for these products.
PIWIL1 Promotes Malignant Progression of Papillary Thyroid Carcinoma
by Inducing EVA1A Expression
Authors: Liu Lianyong , Wu Fengying , Zhang Xiaoying , Li Xiangqi 
Published: July 2023

Introduction:
Papillary thyroid carcinoma (PTC) is the most common subtype of thyroid
cancer. Previous studies have reported on the ectopic expression of P-element-induced wimpy testis
ligand 1 (PIWIL1) in various human cancers, but its role in PTC progression has not been investigated.

Methods:
In this study, we measured the expression levels of PIWIL1 and Eva-1 homolog A (EVA1A)
in PTC using qPCR and WB. We performed a viability assay to evaluate PTC cell proliferation and
used flow cytometry to investigate apoptosis. Moreover, we conducted a Transwell invasion assay to
quantify cell invasion and assessed PTC growth in vivo using xenograft tumor models.

Results:
Our findings showed PIWIL1 to be highly expressed in PTC and promote cell proliferation,
cell cycle activity, and cell invasion, while suppressing apoptosis. Additionally, PIWIL1 accelerated
tumor growth in PTC xenografts by modulating the EVA1A expression.

Conclusion:
Our study suggests that PIWIL1 contributes to the progression of PTC through EVA1A
signaling, indicating its potential role as a therapeutic target for PTC. These results provide valuable
insights into PIWIL1 function and may lead to more effective treatments for PTC.
Development of an Efficient Process for a Diagnostic Test Agent (Bentiromide)
and Identification, Synthesis, Characterization, and Control
Strategy for Potential Impurities
Authors: Naramsetti Kiran Kumar , Alluri Chandramohan , Sharma G. Veera Raghava 
Published: July 2023

Abstract:
The latest development studies provide a more effective and suitable process for Bentiromide
(1), a diagnostic test substance. The enhanced procedure includes process modifications to
get a better yield (76%) and high purity (above 99.8%) of Bentiromide (1). The current studies also
outline a commercially viable method for removing important process-related impurities (A, B, C, D,
E, F & G) in Bentiromide (1). During the impurity profile research, seven critical process-related impurities
were found. These impurities were identified using high-performance liquid chromatography
(HPLC) and liquid chromatography-mass spectrometry (LC-MS) techniques. The synthesis schemes
and spectral analysis data (MS, IR, 1H NMR, and 13C NMR) were used to characterize and confirm
these impurities' structures. All of these impurities sources were investigated, identified, and strict
control measures were taken to reduce them to an acceptable level.
Deep Learning–Assisted Gait Parameter Assessment for Neurodegenerative Diseases: Model Development and Validation
Authors: Jing Yu , Qin Peinuan , Fan Xiangmin , Qiang Wei , Wencheng Zhu , Sun Wei , Tian Feng , Wang Dakuo 
Published: July 2023

Background
Neurodegenerative diseases (NDDs) are prevalent among older adults worldwide. Early diagnosis of NDD is challenging yet crucial. Gait status has been identified as an indicator of early-stage NDD changes and can play a significant role in diagnosis, treatment, and rehabilitation. Historically, gait assessment has relied on intricate but imprecise scales by trained professionals or required patients to wear additional equipment, causing discomfort. Advancements in artificial intelligence may completely transform this and offer a novel approach to gait evaluation.

Objective
This study aimed to use cutting-edge machine learning techniques to offer patients a noninvasive, entirely contactless gait assessment and provide health care professionals with precise gait assessment results covering all common gait-related parameters to assist in diagnosis and rehabilitation planning.

Methods
Data collection involved motion data from 41 different participants aged 25 to 85 (mean 57.51, SD 12.93) years captured in motion sequences using the Azure Kinect (Microsoft Corp; a 3D camera with a 30-Hz sampling frequency). Support vector machine (SVM) and bidirectional long short-term memory (Bi-LSTM) classifiers trained using spatiotemporal features extracted from raw data were used to identify gait types in each walking frame. Gait semantics could then be obtained from the frame labels, and all the gait parameters could be calculated accordingly. For optimal generalization performance of the model, the classifiers were trained using a 10-fold cross-validation strategy. The proposed algorithm was also compared with the previous best heuristic method. Qualitative and quantitative feedback from medical staff and patients in actual medical scenarios was extensively collected for usability analysis.

Results
The evaluations comprised 3 aspects. Regarding the classification results from the 2 classifiers, Bi-LSTM achieved an average precision, recall, and F1-score of 90.54%, 90.41%, and 90.38%, respectively, whereas these metrics were 86.99%, 86.62%, and 86.67%, respectively, for SVM. Moreover, the Bi-LSTM–based method attained 93.2% accuracy in gait segmentation evaluation (tolerance set to 2), whereas that of the SVM-based method achieved only 77.5% accuracy. For the final gait parameter calculation result, the average error rate of the heuristic method, SVM, and Bi-LSTM was 20.91% (SD 24.69%), 5.85% (SD 5.45%), and 3.17% (SD 2.75%), respectively.

Conclusions
This study demonstrated that the Bi-LSTM–based approach can effectively support accurate gait parameter assessment, assisting medical professionals in making early diagnoses and reasonable rehabilitation plans for patients with NDD.
Changes in Documentation Due to Patient Access to Electronic Health Records: Protocol for a Scoping Review
Authors: Meier-Diedrich Eva , Davidge Gail , Hägglund Maria , Kharko Anna , Lyckblad Camilla , McMillan Brian , Blease Charlotte , Schwarz Julian 
Published: July 2023

Background
Internationally, patient-accessible electronic health records (PAEHRs) are increasingly being implemented. Despite reported benefits to patients, the innovation has prompted concerns among health care professionals (HCPs), including the possibility that access incurs a “dumbing down” of clinical records. Currently, no review has investigated empirical evidence of whether and how documentation changes after introducing PAEHRs.

Objective
This paper presents the protocol for a scoping review examining potential subjective and objective changes in HCPs documentation after using PAEHRs.

Methods
This scoping review will be carried out based on the framework of Arksey and O’Malley. Several databases will be used to conduct a literature search (APA PsycInfo, CINAHL, PubMed, and Web of Science Core Collection). Authors will participate in screening identified papers to explore the research questions: How do PAEHRs affect HCPs’ documentation practices? and What subjective and objective changes to the clinical notes arise after patient access? Only studies that relate to actual use experiences, and not merely prior expectations about PAEHRs, will be selected in the review. Data abstraction will include but will not be limited to publication type, publication year, country, sample characteristics, setting, study aim, research question, and conclusions. The Mixed Methods Appraisal Tool will be used to assess the quality of the studies included.

Results
The results from this scoping review will be presented as a narrative synthesis structured along the key themes of the corpus of evidence. Additional data will be prepared in charts or tabular format. We anticipate the results to be presented in a scoping review at a later date. They will be disseminated at scientific conferences and through publication in a peer-reviewed journal.

Conclusions
This is the first scoping review that considers potential change in documentation after implementation of PAEHRs. The results can potentially help affirm or refute prior opinions and expectations among various stakeholders about the use of PAEHRs and thereby help to address uncertainties. Results may help to provide guidance to clinicians in writing notes and thus have immediate practical relevance to care. In addition, the review will help to identify any substantive research gaps in this field of research. In the longer term, our findings may contribute to the development of shared documentation guidelines, which in turn are central to improving patient communication and safety.

International Registered Report Identifier (IRRID)
PRR1-10.2196/46722
EJERCITO MI CEREBRO DURANTE EL CONFINAMIENTO
Authors: Díaz-Díaz Jorge , Carriedo Alejandro 
Published: July 2023

Durante el periodo de confinamiento domiciliario, el sistema educativo tuvo que adaptarse a unas circunstancias sin precedentes. En este trabajo se muestra una propuesta educativa implementada de manera telemática. El proyecto “Ejercito mi cerebro” se basa en la neuroeducación física y específicamente en el programa neuroeducativo HERVAT que se desarrolló mediante 8 sesiones diferentes a lo largo de dos meses. Las familias recibían las instrucciones al principio de la semana y los niños tenían que hacer las tareas propuestas durante 20-25 minutos todos los días antes de realizar sus actividades curriculares. Participaron 19 niños y se recogió información de 12 familiares que rellenaron un cuestionario online en el que reflejaron sus percepciones y valoraciones sobre el proyecto. Los resultados revelaron altos niveles de interés situacional y de satisfacción por parte de las familias en relación a esta experiencia. También se observó que durante el confinamiento se incrementó notablemente el tiempo de juego con sus hijos. En este sentido, se detectó que los familiares que dedicaban más tiempo a jugar con sus hijos/as (antes y durante el confinamiento) percibieron mayor disfrute durante el desarrollo del proyecto.
Experience of innovation management in the process of creation and implementation of inventions
Authors: Spasennikov V. V. 
Published: July 2023

The purpose of this article is to highlight the Soviet experience of the author as head of a creative team involved in transforming research results into formalized inventions. As a result of cooperation between the industrial research institute and the military enterprise, these inventions were introduced into prototypes of new equipment. The research methodology used in this article includes analysis of patent activity, questionnaire surveys, the nonparametric sociometry method, and a methodology for assessing the satisfaction of inventive activity.The article discusses the challenge of increasing the patent activity of domestic inventors of new technology and how this can be achieved using economic and psychological factors of creative participation such as sociometric coherence, emotional-volitional unity, and intellectual and creative potential. It is important to note that the effectiveness of research in scientific and inventive activities can be assessed using financial, personnel, innovation, and scientometric indicators. Additionally, promising directions of inventive activity in the ergonomic support of the creation of new systems of products and technologies are outlined.
Peningkatan keterampilan passing bawah peserta didik dalam permainan bola voli melalui metode drill dengan bantuan alat modifikasi bola gantung
Authors: Fatchur M. 
Published: July 2023

Studi pendahuluan menunjukkan rendahnya keterampilan teknik passing bawah pesera didik dalam permainan bola voli karena bola yang digunakan berukuran standar serta dianggap terlalu keras dan menimbulkan rasa sakit pada tangan. Selain itu, waktu pembelajaran tidak efektif karena waktu banyak digunakan untuk memungut bola yang lepas dari kontrol. Permasalahan diperparah dengan kurangnya sarana prasarana sekolah dalam permainan bola voli. Permasalahan ini perlu diperbaiki agar tidak menurunkan minat dan motivasi peserta didik dalam mata pelajaran Penjasorkes. Penelitian ini merupakan penelitian tindakan kelas (PTK) yang bertujuan meningkatkan keterampilan passing bawah peserta didik dalam permainan bola voli menggunakan metode drill berbantuan alat modifikasi bola gantung. Penelitian dilaksanakan pada 1 sampai 22 Agustus 2022 selama dua siklus yang masing-masing mencakup tindakan perencanaan, tindakan, observasi, dan refleksi dalam setiap siklusnya. Sejumlah 32 peserta didik kelas VII A SMP Negeri 1 Juwangi semester gasal tahun pelajaran 2022/2023 yang terdiri atas 18 putra dan 14 putri menjadi subjek penelitian. Peneliti menggunakan teknik tes, survei, dokumentasi, dan wawancara dalam pengumpulan data. Instrumen penelitian mengadopsi instrumen penelitian terdahulu dan divalidasi ahli. Data dianalisis secara deskriptif komparatif. Hasil penelitian menunjukkan bahwa (1) rata-rata nilai keterampilan passing bawah pada Siklus 2 meningkat sampai dengan 82,81, (2) ketuntasan klasikal kelas pada Siklus 2 meningkat sampai dengan 84,38%, dan (3) rata-rata nilai partisipasi peserta didik dalam pembelajaran Siklus 2 diketahui sebesar 78,91, atau tergolong aktif. Hasil penelitian memotivasi rekan-rekan sejawat peneliti untuk memperbaiki kualitas pembelajaran melalui penelitian tindakan kelas. Penelitian ini tidak memperhitungkan peningkatan keterampilan yang diperoleh peserta didik akibat pelatihan di luar pembelajaran.
Efektivitas Stretching PNF Terhadap Kelenturan
Authors: Al Fajar Hafiz , Samodra Y. touvan juni , Wati Isti dwi puspita , Yosika Ghana Firsta , Gandasari Maharani Fatima , Sofyan Davi 
Published: July 2023

Tujuan dari penelitian ini adalah untuk mengetahui tingkat efektivitas Stretching PNF pada kelenturan untuk meningkatkan fleksibilitas. Metode penelitian dengan menggunakan eksperimen One Group Pretest- Postest design. Sampel yang digunakan adalah mahasiswa/i Universitas Tanjungpura Prodi Pendidikan Kepelatihan Olahraga berjumlah 10 orang. Penelitian ini dilakukan dengan menggunakan treatmeant 3 gerakan stretching PNF, dengan gerakan Hold Relax Hamstring, Quadriceps, Chest PNF. Kemudian diukur dengan sit and reach sebelum dan sesudah perlakuan (treatmeant). Teknik analisis data menggunakan deskriptif dan uji t. Hasil penelitian ini mengungkapkan terdapat perbedaan antara sebelum dan sesudah perlakuan sebesar 1,8 cm. Maka dengan dapat simpulkan bahwa dengan adanya peregangan PNF dapat meningkatkan kelenturan
New approach to regularise the perturbed two-body problem
Authors: Alhowaity Sawsan , Selim H. H. , Gao Fabao , Pathak Niraj M. , Abouelmagd Elbaz I. 
Published: July 2023

Abstract
This work aims to construct a new regularisation version for the perturbed two-body problem using bipolar coordinates. We mainly use two transformation techniques to deal with this problem when the distance between two bodies tends to be zero. The system exhibits a well-stabilised periodic orbit over a long time span through numerical simulations. With the increase in the oblate parameter value of the body, the periodic orbit will gradually evolve into a quasi-periodic form.