bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence of the anterosuperior capsulolabral anatomical variations and their association with pathologies of the glenoid labrum: a systematic review and meta-analysis
Authors: Benes Michal , Kachlik David , Kopp Lubomir , Kunc Vojtech 
Published: June 2023

Abstract
Purpose
Differentiating the anatomical variations of the anterosuperior portion of the glenoid labrum from pathologies is important to avoid unnecessary iatrogenic complications resulting from inaccurate diagnosis. Additionally, the presence of several variations was reported to be conductive to lesions involving the glenoid labrum. Thus, the aim of this study was to state the prevalence rates of the sublabral recess, sublabral foramen, and the Buford complex, and to verify their association with labral lesions.

Methods
Systematic search of electronic databases was conducted to gain potentially eligible literature. Suitable studies were selected in a two-round screening, and relevant data were subsequently extracted. Calculation of the pooled prevalence estimates, including sub-analyses on cohort size, study type, and geographical variance, was conducted. Pooled analysis of risk ratios (RR) was used to assess the conductive nature of the discussed variants to superior labrum anterior to posterior (SLAP) lesions.

Results
The screening resulted in selection of 20 studies investigating the morphological features of the glenoid labrum, consisting of 7601 upper limbs. On the bases of random-effects meta-analysis the sublabral recess, sublabral foramen and Buford complex occur with a pooled prevalence of 57.2% (95% CI 30.0–84.4%), 13.5% (95% CI 8.2–18.9%), and 3.0% (95% CI 1.5–4.5), respectively. Moreover, individuals with Buford complex have RR 2.4 (95% CI 1.3–4.7) of developing SLAP lesions, especially type II (95.5%; 95% CI 86.1–100%), whereas such risk for sublabral recess and sublabral foramen was not statistically significant.

Conclusion
Morphological variants of the glenoid labrum posing diagnostic confusion are frequently observed. Gradually, the Buford complex may be a predisposing factor for sustaining a SLAP lesion.
The impact of the SARS-CoV-2 pandemic-related lockdowns on orthopedic trauma emergencies at a level-one trauma center
Authors: Messler Valentin , Leschinger Tim , Ott Nadine , Rausch Valentin , Burst Volker , Eysel Peer , Müller Lars Peter , Hackl Michael 
Published: June 2023

Abstract
Introduction
The SARS-CoV-2 pandemic and its associated lockdowns had a profound effect on orthopedic trauma emergencies. This study aimed to investigate the patient volume and injury patterns at a level-one trauma center during the SARS-CoV-2 pandemic and compare them to the pre-pandemic conditions.

Materials and methods
A retrospective chart review of all patients who presented to the orthopedic trauma emergency department of a level-one trauma center in Cologne, Germany within a 2 year period from March 16th, 2019 to March 15th, 2020 (pre-pandemic control) and from March 16th, 2020 and March 15th, 2021 (pandemic) was performed. The pandemic year was separated into three periods: (1) first lockdown, (2) between lockdowns and (3) second lockdown. The absolute numbers of patient presentations, the Manchester triage score (MTS) and the relative proportion of patients with structural organ injuries, fractures and dislocations, of polytraumatized patients, of hospital admissions, of subsequent emergency or semi-elective surgeries and of work-related accidents were evaluated in comparison to the pre-pandemic control.

Results
A total of 21,642 patient presentations were included in this study. Significantly less weekly orthopedic trauma emergency patient presentations were recorded during the pandemic (p < 0.01).
The MTS was significantly lower during the first lockdown and between lockdowns (p < 0.01). The proportional incidence of overall structural organ injuries, fractures and dislocations, of upper limb fractures/dislocations, of hospital admissions and of patients requiring surgery was significantly increased during the pandemic (p ≤ 0.03). The proportional incidence of work-related injuries was significantly decreased during the pandemic (p < 0.01).

Conclusions
Orthopedic trauma emergency presentations were reduced during the SARS-CoV-2 pandemic. Due to the reluctancy of patients to visit the emergency department during the pandemic, the proportions of relevant injuries in general and of upper limb injuries in particular as well as of patients requiring hospital admission and trauma-related surgery were significantly increased.
The double-plate fixation technique prevents varus collapse in AO type C3 supra-intercondylar fracture of the distal femur
Authors: Liu Chang-Heng , Tsai Ping-Jui , Chen I-Jung , Yu Yi-Hsun , Chou Ying-Chao , Hsu Yung-Heng 
Published: June 2023

Abstract
Introduction
Varus collapse followed by osteosynthesis for distal femoral fractures with conventional implants has been well documented but is seldom mentioned in fractures managed with locking plates. The purpose of this study was to assess the incidence of varus collapse after treating complex supra-intercondylar fractures of the distal femur (AO type C3) using a Single Plate (SP) or Double Plate (DP) fixation technique.

Materials and methods
We retrospectively reviewed 357 patients with distal femoral fractures who were treated at our hospital between 2006 and 2017. After excluding cases of infection, malignancy, periprosthetic fracture, revision surgery, pediatric fracture, and extra-articular fracture, 54 patients were included in the study. All demographic data and radiological and clinical outcomes were reviewed and analyzed.

Results
There were 54 patients enrolled into this study with age from 15 to 85 years old (mean 41.6, SD = 19.9), and 32 of them were open fractures (59%). The patients were further divided into either an SP (n = 15) or a DP group (n = 39). Demographics, including age, sex, injury severity score, and open fracture type, were all compatible between the two groups. The overall nonunion rate was 25.9% (n = 14; 6 from the SP and 8 from the DP group; p = 0.175). The varus collapse rate was 9.3% (n = 5; 4 from the SP and 1 from the DP group (p = 0.018).

Conclusions
The varus collapse rate after osteosynthesis with a single lateral locking plate could be as high as 26.7% in AO type C3 fractures of the distal femur, which would be decreased to 2.6% by adding a medial buttress plate. Surgeons should consider DP fixation to avoid varus collapse in severely comminuted complete intra-articular fractures of the distal femur.
Diagnostic gastrointestinal markers in primary lung cancer and pulmonary metastases
Authors: Malmros Karina , Lindholm Andreas , Vidarsdottir Halla , Jirström Karin , Nodin Björn , Botling Johan , Mattsson Johanna S. M. , Micke Patrick , Planck Maria , Jönsson Mats , Staaf Johan , Brunnström Hans 
Published: June 2023

AbstractHistopathological diagnosis of pulmonary tumors is essential for treatment decisions. The distinction between primary lung adenocarcinoma and pulmonary metastasis from the gastrointestinal (GI) tract may be difficult. Therefore, we compared the diagnostic value of several immunohistochemical markers in pulmonary tumors. Tissue microarrays from 629 resected primary lung cancers and 422 resected pulmonary epithelial metastases from various sites (whereof 275 colorectal cancer) were investigated for the immunohistochemical expression of CDH17, GPA33, MUC2, MUC6, SATB2, and SMAD4, for comparison with CDX2, CK20, CK7, and TTF-1. The most sensitive markers for GI origin were GPA33 (positive in 98%, 60%, and 100% of pulmonary metastases from colorectal cancer, pancreatic cancer, and other GI adenocarcinomas, respectively), CDX2 (99/40/100%), and CDH17 (99/0/100%). In comparison, SATB2 and CK20 showed higher specificity, with expression in 5% and 10% of mucinous primary lung adenocarcinomas and both in 0% of TTF-1-negative non-mucinous primary lung adenocarcinomas (25–50% and 5–16%, respectively, for GPA33/CDX2/CDH17). MUC2 was negative in all primary lung cancers, but positive only in less than half of pulmonary metastases from mucinous adenocarcinomas from other organs. Combining six GI markers did not perfectly separate primary lung cancers from pulmonary metastases including subgroups such as mucinous adenocarcinomas or CK7-positive GI tract metastases. This comprehensive comparison suggests that CDH17, GPA33, and SATB2 may be used as equivalent alternatives to CDX2 and CK20. However, no single or combination of markers can categorically distinguish primary lung cancers from metastatic GI tract cancer.
Propagation of chaos for maxima of particle systems with mean-field drift interaction
Authors: Kolliopoulos Nikolaos , Larsson Martin , Zhang Zeyu 
Published: June 2023

AbstractWe study the asymptotic behavior of the normalized maxima of real-valued diffusive particles with mean-field drift interaction. Our main result establishes propagation of chaos: in the large population limit, the normalized maxima behave as those arising in an i.i.d. system where each particle follows the associated McKean–Vlasov limiting dynamics. Because the maximum depends on all particles, our result does not follow from classical propagation of chaos, where convergence to an i.i.d. limit holds for any fixed number of particles but not all particles simultaneously. The proof uses a change of measure argument that depends on a delicate combinatorial analysis of the iterated stochastic integrals appearing in the chaos expansion of the Radon–Nikodym density.
Limited impact of chytridiomycosis on juvenile frogs in a recovered species
Authors: Hollanders Matthijs , Grogan Laura F. , McCallum Hamish I. , Brannelly Laura A. , Newell David A. 
Published: June 2023

AbstractThe amphibian chytrid fungus Batrachochytrium dendrobatidis (Bd) has caused catastrophic frog declines on several continents, but disease outcome is mediated by a number of factors. Host life stage is an important consideration and many studies have highlighted the vulnerability of recently metamorphosed or juvenile frogs compared to adults. The majority of these studies have taken place in a laboratory setting, and there is a general paucity of longitudinal field studies investigating the influence of life stage on disease outcome. In this study, we assessed the effect of endemic Bd on juvenile Mixophyes fleayi (Fleay’s barred frog) in subtropical eastern Australian rainforest. Using photographic mark-recapture, we made 386 captures of 116 individuals and investigated the effect of Bd infection intensity on the apparent mortality rates of frogs using a multievent model correcting for infection state misclassification. We found that neither Bd infection status nor infection intensity predicted mortality in juvenile frogs, counter to the expectation that early life stages are more vulnerable to disease, despite average high infection prevalence (0.35, 95% HDPI [0.14, 0.52]). Additionally, we found that observed infection prevalence and intensity were somewhat lower for juveniles than adults. Our results indicate that in this Bd-recovered species, the realized impacts of chytridiomycosis on juveniles were apparently low, likely resulting in high recruitment contributing to population stability. We highlight the importance of investigating factors relating to disease outcome in a field setting and make recommendations for future studies.
Psycho-oncologists’ knowledge of cancer-related fatigue and the targets for improving education and training: results from a cross-sectional survey study
Authors: Milzer Marlena , Wagner Anna S. , Steindorf Karen , Kiermeier Senta , Schmidt Martina E. , Maatouk Imad 
Published: June 2023

Abstract
Purpose
To explore psycho-oncologists’ knowledge of cancer-related fatigue and their self-efficacy to intervene for fatigue. We further aimed to examine the role of fatigue in psycho-oncological training and derive specific suggestions for improvements.

Methods
For this cross-sectional survey study, psycho-oncologists working in Germany were systematically recruited via an address directory or invited by training institutes or colleagues. The online survey encompassed questions on knowledge of fatigue guidelines and interventions, self-efficacy, counseling, and fatigue in professional training. Data were analyzed descriptively and using Mann-Whitney U tests. A logistic regression analysis was performed to identify variables linked to fatigue guideline knowledge.

Results
Seventy two percent of the 144 surveyed psycho-oncologists stated not knowing any fatigue-specific guidelines. Those unaware of guidelines reported a lower self-efficacy to intervene for fatigue. However, despite low knowledge of the guidelines, more than 80% of the participants felt well informed about fatigue and reported high self-efficacy. Most participants were aware of the empirical evidence for psychotherapeutic interventions (95%); everyday physical activity, e.g., taking a walk (98%); yoga (82%); and mindfulness-based interventions (82%). Knowledge gaps existed concerning the evidence of resistance/endurance training for treating fatigue. Knowing that resistance/endurance training is an effective treatment was related to an increased frequency to recommend it to patients. Suggestions to improve training for psycho-oncologists included raising awareness earlier in the career path and offering multidisciplinary trainings for fatigue.

Conclusion
To improve fatigue-related guideline knowledge among psycho-oncologists and enhance implementation into clinical practice multidisciplinary trainings are needed. Psycho-oncologists should play an important role in fatigue management.

Trial registration
Clinicaltrials.gov, identifier: NCT04921644. Registered in June 2021.
Medial migration of the helical blade with penetration into the acetabulum: a rare complication using the TFNA nail
Authors: Deichsel Adrian , Katthagen J. Christoph , Raschke Michael J. , Riesenbeck Oliver 
Published: June 2023

Abstract
Purpose
To determine the frequency and possible reasons of medial migration with penetration into the acetabulum (MMPA) of the helical blade when using the Trochanteric Fixation Nail Advanced (TFNA) is used for treatment of pertrochanteric fractures.

Methods
All patients with pertrochanteric femoral fracture, treated by intramedullary femoral nailing with the TFNA, were retrospectively reviewed for MMPA of the helical blade. Epidemiological parameters, additional procedures, distance of medial migration, time from primary operation to revision as well as type of revision were assessed.

Results
4 of 153 patients treated with the TFNA developed an MMPA of the helical blade (risk = 2.6%), with a mean medial migration of the blade of 11.6 mm (SD 8.8). The mean time from initial operation to revision surgery was 70 days (SD 30). All patients were revised by conversion to cemented total hip arthroplasty.

Conclusion
MMPA of the helical blade is a rare but potentially hazardous complication of femoral nailing with the TFNA femoral nail, resulting in the necessity for revision surgery and total hip arthroplasty.
Spinal fusion for single-level SPECT/CT positive lumbar degenerative disc disease: the SPINUS I study
Authors: Kaiser Radek , Varga Michal , Lang Otto , Waldauf Petr , Vaněk Petr , Saur Karel , Beneš Vladimír , Netuka David 
Published: June 2023

Abstract
Introduction and purpose
With current imaging modalities and diagnostic tests, identifying pain generators in patients with non-specific chronic low back pain (CLBP) is difficult. There is growing evidence of the effectiveness of SPECT/CT examination in diagnosing the source of pain in the spine. The study aims to investigate the effect of posterior interbody fusion on a single-level SPECT/CT positive lumbar degenerative disc disease (DDD).

Material and methods
This is a prospective study of patients with chronic low back pain (CLBP) operated on for a single-level SPECT/CT positive DDD. Primary outcomes were changes in visual analogue scale (VAS) scores and the Oswestry Disability Index (ODI). Secondary outcomes were complications, return to work, satisfaction and willingness to re-undergo surgery.

Results
During a 3-year period, 38 patients underwent single-level fusion surgery. The mean preoperative VAS score of 8.4 (± 1.1) decreased to 3.2 (± 2.5, p < 0.001) and the mean preoperative ODI of 51.5 (± 7.3) improved to 20.7 (± 14.68, p < 0.001) at a 2-year follow-up. A minimum clinically important difference (30% reduction in VAS and ODI) was achieved in 84.2% of patients. Some 71% of patients were satisfied with the surgery results and 89.4% would undergo surgery again. There were four complications, and two patients underwent revision surgery. Some 82.9% of patients returned to work.

Conclusion
Fusion for one-level SPECT/CT positive lumbar DDD resulted in substantial clinical improvement and satisfaction with surgical treatment. Therefore, SPECT/CT imaging could be useful in assessing patients with CLBP, especially those with unclear MRI findings.

Trial registration
ClinicalTrials.gov Identifier: NCT04876586.
Rainfall disparity at monthly scale on Catalonia (NE Spain): dependence on geographic coordinates, altitude and distance to the Mediterranean coast
Authors: Lana Xavier , Rodríguez-Solà Raúl , del Carmen Casas-Castillo María , Serra Carina , Kirchner Ricard , Martínez Maria Dolors 
Published: June 2023

AbstractThe rainfall regime in Catalonia, NE Spain, has a typical Mediterranean behaviour with irregular monthly amounts, sometimes the result of copious and intense torrential episodes for a few months, while for others precipitation is scarce. In addition, the varied topography of this region is related to significant rainfall differences between its different areas. The monthly precipitation from 97 stations spread throughout the territory, from 1950 to 2016, has allowed a detailed study of the spatial distribution of rainfall irregularity, based on the concept of disparity, D. The disparities have been calculated for every calendar month, to characterise the rainfall amount inter-annual oscillations, and also for all the consecutive months, to evaluate the rainfall disparity along the year. The spatial distribution of D has been obtained for all cases, showing a main general increase from North to South, and a secondary increase from West to East, in some months such as July. The winter months, especially January, have the highest values of D, which can reach the value of 2.0. The dependence of D on altitude and distance from the coast has also been analysed. The correlation is predominantly negative in both cases, although in some months, such as January, this correlation is not so clear. Additionally, the histograms of D show statistical characteristics, such as signs of a Gaussian distribution for some calendar months, as well as clear asymmetry in others. The obtained results could be interesting to detect the calendar months with the highest uncertainty on their expected rain amounts, contributing to a better knowledge of the complex structure of the rainfall Mediterranean regime.
Identity and purity of historical remains of inorganic pharmaceuticals from the eighteenth century
Authors: Nesměrák Karel , Janoušková Eva , Červený Václav , Hraníček Jakub , Šimonová Alice , Kunešová Jana , Němec Ivan 
Published: June 2023

AbstractSixteen specimens of historical remains of inorganic pharmaceuticals dating back to the eighteenth century were analyzed by a combination of spectroscopy (ICP–MS, atomic absorption/emission, UV–Vis, infrared and Raman), capillary zone electrophoresis, and chemical methods (titration and gravimetric analysis). The results obtained confirmed the identity of 14 of the specimens analyzed. With the exception of one, impurities were found in all specimens, often at relatively high concentrations. Based on these impurities, it was possible to confirm the origin of six substances as naturally occurring minerals. The other specimens were probably prepared by period apothecaries or artisans through chemical reactions. In two specimens, a recipe of the time, based on the ignition of metal with sulfur, could be confirmed. For anatron, a substance that originated as a by-product of glass melting, it was possible to determine its composition as a mixture of alkaline sulfates, carbonates, and chlorides (the first such analysis described in the literature). On the other hand, for two specimens, it was found that the substance was mistaken for a completely different compound than would be expected from the Latin inscription on the apothecary jar.
Graphical abstract
Women’s experiences of specialist perinatal mental health services: a qualitative evidence synthesis
Authors: Moran Emma , Noonan Maria , Mohamad Mas Mahady , O’Reilly Pauline 
Published: June 2023

Abstract
Purpose
Specialist perinatal mental health services identify and treat women experiencing mental health conditions during pregnancy and up to one year post birth. There is limited knowledge about women’s experiences of care from specialist services. Evaluation and optimisation of service delivery requires knowledge of women’s care experiences. This review aimed to systematically identify, appraise, and synthesise qualitative evidence exploring women’s experiences of specialist perinatal mental health services.

Methods
A systematic literature search of five databases: Medline (OVID), EMBASE (Elsevier), PsycINFO (EBSCO), CINAHL (EBSCO) and Scopus (Elsevier), grey literature searching, and backward citation, identified a total of 1035 papers of which sixteen met inclusion criteria. Methodological quality of the included studies was assessed using the Critical Appraisal Skills Program (CASP) tool.

Results
Thematic synthesis identified three themes: connected relationships; new beginnings; and meaningful service delivery. Findings identified that relationships developed with clinicians were significant to women and their experience of care. Women valued continuity of care from dedicated non-judgemental clinicians. Peer support from other mothers was perceived as meaningful to women. Through service interventions women gained new insights into their infant’s needs and grew in confidence as a mother.

Conclusions
Women require provision of flexible and accessible specialist services with clinicians who are sensitive to their individual psychosocial needs and preferences. Examining discharge practices and continuing care needs is essential to ensure the best outcomes for women and their families.
Knowledge representation of the state of a cloud-native application
Authors: Kosińska Joanna , Brotoń Grzegorz , Tobiasz Maciej 
Published: June 2023

AbstractCloud Computing has revolutionized the way applications are developed, deployed, and maintained. Over the past decade, we have observed dynamically growing interest in Cloud Computing. The benefits of the cloud approach caused the increasing popularity of Cloud-native applications. Cloud-native is an approach to developing and deploying applications according to the concepts of DevOps, Continuous Integration/Continuous Delivery (CI/CD), containers and microservices. The knowledge about Cloud Computing has become extensive and complex. Fortunately, before Cloud-native applications development, there was a great deal of effort to develop tools for effective knowledge representation. Ontologies are a convenient way to show the relations between domain-specific concepts. In this paper, we propose an ontology named CNOnt that describes the state-of-the-art of Cloud-native applications. CNOnt covers aspects from the clusterization perspective. First, this paper presents the engineering perspective of building the CNOnt ontology. Second, we demonstrate a use case of our ontology that proves the correctness of CNOnt development. This ontology is exhausted in CNOnt Broker. It is a system that applies the information in the OWL file into the Kubernetes cluster and in reverse. The knowledge representation makes Cloud-native applications understandable to third-party systems and increases interoperability between different microservices.