bluuebunny/crossref_metadata_2025_split huggingface dataset:
The role of mindfulness and compassion in early adults' subsequent mental health, coping and compliance with health guidelines during the COVID‐19 pandemic: A prospective longitudinal study
Authors: Van Doren Natalia , Mahlobo Christa T. , Galla Brian M. , Colaianne Blake A. , Hirshberg Matthew J. , Inkelas Karen Kurotsuchi , Roeser Robert W. 
Published: August 2023

AbstractThe present study explored prospective links between trait mindfulness and compassion on subsequent coping and compliance with Centers for Disease Control (CDC) guidelines and indirect effects via well‐being and internalized distress during the COVID‐19 pandemic. The study included N = 736 US college students who participated in a three‐wave longitudinal study across a single academic year. The first two assessment waves took place in 2018 and 2019, respectively, while the third wave took place in May 2020 during the COVID‐19 pandemic. Participants completed self‐report measures of trait mindfulness, compassion, well‐being, internalized distress, coping, and compliance with CDC health guidelines. Results of a series of autoregressive, cross‐lagged panel models revealed that trait mindfulness was associated with better coping via indirect effects of greater well‐being and lower internalized distress. Greater compassion was linked with greater adherence to CDC guidelines. Findings suggest that trait mindfulness and compassion may play a role in college students' coping and compliance during the pandemic.
Connections between cohesion and properties that related to safety and effectiveness of the hyaluronic acid dermal fillers: A comparative study of the cohesive and non‐cohesive gels
Authors: Wang Xiaotong , Xi Hongwei , Wei Changzheng 
Published: August 2023

AbstractBackgroundAlthough the importance of the cohesion of a hyaluronic acid (HA) filler has been recognized, the relationship between the cohesion and the other performance that related to safety and effectiveness, as well as the underlying mechanism is barely studied. Much efforts need to be made on this subject to provide guidance for clinical practice.Materials and methodsTwo types of the HA fillers (cohesive and particulate gels) were selected for the comparison of the cohesion and the other key physicochemical properties.ResultsHyalumatrix, with significantly higher cohesion, was homogeneously smooth and showed a linearly oriented morphology, whereas Matrifill and Restylane were particulate and showed obvious boundaries between particles. The high cohesion of Hyalumatrix is beneficial to the properties that related to safety and effectiveness, including recovery under shear stress, injectability, tissue integration and in vitro resistance to enzymolysis. The underlying reason was that the strong internal interactions of the cohesive gel protect the network structure from collapse and keep the gel as an intact whole when the gel was subjected to the stress. The homogeneously smooth morphology further improved the tissue compliance and injectability. The G′ of Hyalumatrix is in the middle level of the commercially available HA fillers.ConclusionHyalumatrix is a rare HA filler product to possess good cohesion and intermediate G′ simultaneously. More clinical practice is needed to verify the connection between the cohesion of Hyalumatrix and the clinical performance.
Are images worth a thousand words? A preliminary study testing a video for owner education in canine atopic dermatitis
Authors: Fernandes Beatriz , Cavaco Afonso , Pinto Marta , Bizarro Ana Filipa , Pereira Hugo , Lourenço Ana Mafalda 
Published: August 2023

AbstractBackgroundSuccessful management of canine atopic dermatitis (cAD) is challenging and effective pet owner education is crucial to successful outcomes. However, there are limited proven educational strategies in this area. Our goal was to create an effective and engaging educational tool for owners of dogs with cAD.HypothesisVideo‐based education efficacy would be comparable to traditional verbal delivery. Secondary objectives included assessing client perception of the intervention, and determining if there were clinical benefits for the dogs and improved client adherence to treatment.SubjectsTwenty‐nine dogs with cAD and their owners were recruited from a teaching hospital of a European veterinary medicine faculty.Materials and MethodsIn this 8 week, prospective, randomised controlled study, clients in the control group (CG, n = 13) received verbal education and those in the intervention group (IG, n = 16) watched a video. Client knowledge was assessed at Day (D)0 and D56. Treatment adherence and perceived utility and appeal ratings were measured at D56. Clinical progress was assessed at D0 and D56 using CADESI‐04 and PVAS10.ResultsThe differences found in the means of cAD knowledge score, clinical outcomes, utility and appeal ratings and owners' adherence score between groups were not statistically significant. A significant association between the outcome and the intervention group concerning education success [CG, six of 13 (46.15%); IG, 15 of 16 (93.75%)] was found (p = 0.01).Conclusions and Clinical RelevanceVideo‐based instructions positively impacted owners' education and demonstrated their potential as a valuable tool. The authors believe that video‐based education could be a time‐efficient alternative for initial cAD education in veterinary clinics.
Validation of a human paper‐based blood typing method for use in pet pigs
Authors: Hampton Chiara E. , Zhu Xiaojuan , Giori Luca 
Published: August 2023

AbstractBackgroundEvidence‐based medical practices for pet pigs are needed. EldonCard is a human blood‐typing card shown to be rapid and reliable in identifying blood phenotypes of pet pigs. The objective of this study was to validate EldonCard by determining its reliability, reproducibility, and robustness for its routine use in the clinical setting.Key FindingsTwenty‐four venous blood samples from pet pigs were collected for a prospective in vitro study. Blood genotypes (“EAAA0” and “EAA00”) were identified in 15 samples via polymerase chain reaction (PCR). All samples were phenotyped (“A,” “Aweak,” and “0” or “–”) via EldonCard. Kappa (κ) statistics measured the level of agreement between 2 raters, and between EldonCard and PCR. McNemar's test determined if an association between the blood types and EldonCard or PCR exists, with significance at P < 0.05. Agreement between raters and methods was perfect (60/60 [100%], κ:1, P < 0.001; 15/15 [100%], κ:1, P < 0.001). There was no difference in the proportions of blood groups based on method.SignificanceIn conjunction with previous data, EldonCard is a rapid, accurate, reliable, precise, and robust in‐clinic blood‐typing method for the A0 system of pet pigs. EldonCard is now a validated blood‐typing tool for the A0 system of pet pigs and maybe used for pretransfusion screenings and identification of donors and recipients.
Lax monoidal adjunctions, two‐variable fibrations and the calculus of mates
Authors: Haugseng Rune , Hebestreit Fabian , Linskens Sil , Nuiten Joost 
Published: August 2023

AbstractWe provide a calculus of mates for functors to the ‐category of ‐categories and extend Lurie's unstraightening equivalences to show that (op)lax natural transformations correspond to maps of (co)cartesian fibrations that do not necessarily preserve (co)cartesian edges. As a sample application, we obtain an equivalence between lax symmetric monoidal structures on right adjoint functors and oplax symmetric monoidal structures on the left adjoint functors between symmetric monoidal ‐categories that is compatible with both horizontal and vertical composition of such structures. As the technical heart of the paper, we study various new types of fibrations over a product of two ‐categories. In particular, we show how they can be dualised over one of the two factors and how they encode functors out of the Gray tensor product of ‐categories.
Are physiological oscillationsphysiological?
Authors: Xiong Lingyun (Ivy) , Garfinkel Alan 
Published: August 2023

AbstractDespite widespread and striking examples of physiological oscillations, their functional role is often unclear. Even glycolysis, the paradigm example of oscillatory biochemistry, has seen questions about its oscillatory function. Here, we take a systems approach to argue that oscillations play critical physiological roles, such as enabling systems to avoid desensitization, to avoid chronically high and therefore toxic levels of chemicals, and to become more resistant to noise. Oscillation also enables complex physiological systems to reconcile incompatible conditions such as oxidation and reduction, by cycling between them, and to synchronize the oscillations of many small units into one large effect. In pancreatic β‐cells, glycolytic oscillations synchronize with calcium and mitochondrial oscillations to drive pulsatile insulin release, critical for liver regulation of glucose. In addition, oscillation can keep biological time, essential for embryonic development in promoting cell diversity and pattern formation. The functional importance of oscillatory processes requires a re‐thinking of the traditional doctrine of homeostasis, holding that physiological quantities are maintained at constant equilibrium values, a view that has largely failed in the clinic. A more dynamic approach will initiate a paradigm shift in our view of health and disease. A deeper look into the mechanisms that create, sustain and abolish oscillatory processes requires the language of nonlinear dynamics, well beyond the linearization techniques of equilibrium control theory. Nonlinear dynamics enables us to identify oscillatory (‘pacemaking’) mechanisms at the cellular, tissue and system levels.image
Candida auris
rates in blood culture on the rise: results of US surveillance
Authors: Noble Brooklyn A. , Jurcic Smith Kristen L. , Jones Jay D. , Galvin Ben W. , Timbrook Tristan T. 
Published: August 2023

ABSTRACT

Candida auris
is an emerging pathogen that poses a significant public health risk. Its multidrug resistance has led to high mortality, making rapid detection crucial for effective treatment and prevention of transmission. Recent data from the Centers for Disease Control and Prevention indicate a substantial increase in
C. auris
cases in the United States, with a 95% rise in 2021. To provide an update on the detection rates of
C. auris
, we analyzed blood culture results from a near real-time cloud-based surveillance network, BioFire Trend. From January 2021 to April 2023, 34
C. auris
detections were observed. The analysis showed a notable increase in detections in 2023 compared to previous years. The detection rate in 2023 was higher in all four US Census Regions, except for the Northeast, where it remained constant. The findings emphasize the continuous rise in
C. auris
cases and highlight the importance of near real-time surveillance systems in monitoring this emerging pathogen.
ITV-Pal programme: protocol of evaluation of the implementation of tech-volunteer programme in palliative care services
Authors: Barnestein-Fonseca Pilar , Víbora-Martín Eva , Ruiz-Torreras Inmaculada , Chapinal-Bascón Helena , Martín-Roselló Maria Luisa , Gómez-García Rafael 
Published: August 2023

IntroductionVolunteer support for patients and families at the end of life provides many benefits for the beneficiaries. New technologies could be a necessary resource in the accompaniment although, if there is little literature on palliative care volunteering in general, specifically on volunteering and new technologies, we find little information on the subject.Therefore, the aim of this study is to implement and evaluate a training program for palliative care volunteers using new technologies in order to begin accompanying patients and families in hospital or at home.Methods and analysisA mixed-method study design will be conducted. We will recruit 20 volunteers and 70 patients in two years. Intervention: training of volunteers in new technologies and volunteer accompaniment of patients/relatives using technologies. The control group will accompany patients as usual.Ethics and disseminationEthics approval for the ITV-Pal Programme project was granted by the Malaga Regional Research Ethics Committee. As new knowledge is gained from this project, findings will be disseminated through publications, presentations and feedback to clinicians who are participating in this study.Trial registration numberNCT04900103.
Health seeking behaviours and private sector delivery of care for non-communicable diseases in low- and middle-income countries: protocol for a systematic review
Authors: Brindley Callum , Wijemunige Nilmini , Dieteren Charlotte , Bom Judith , Engel Maarten , Meessen Bruno , Bonfrer Igna 
Published: August 2023

IntroductionThe burden of non-communicable diseases (NCDs) has increased substantially in low- and middle-income countries (LMICs), and adapting health service delivery models to address this remains a challenge. Many patients with NCD seek private care at different points in their encounters with the health system, but the determinants and outcomes of these choices are insufficiently understood. The proposed systematic review will help inform the governance of mixed health systems towards achieving the goal of universal health coverage. This protocol details our intended methodological and analytical approaches, based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA).Methods and analysisFollowing the PRISMA approach, this systematic review will develop a descriptive synthesis of the determinants and outcomes of private healthcare utilisation for NCDs in LMICs. The databases Embase, Medline, Web of Science Core Collection, EconLit, Global Index Medicus and Google Scholar will be searched for relevant studies published in English between period 1 January 2010 and 30 June 2022 with additional searching of reference lists. The study selection process will involve a title-abstract and full-text review, guided by clearly defined inclusion and exclusion criteria. A quality and risk of bias assessment will be done for each study using the Mixed Methods Appraisal Tool.Ethics and disseminationEthical approval is not required because this review is based on data collected from publicly available materials. The results will be published in a peer-reviewed journal and presented at related scientific events.PROSPERO registration numberCRD42022340059
Supportive care needs of patients who had a stroke: a scoping review protocol
Authors: Zhang Huimin , Xu Ke , Ma Jun Yan , Zhang Xiao Yan , Sun Yu Yan , Xiao Lily Dongxia , Yan Fang , Luo Yan Yan , Tang Siyuan 
Published: August 2023

IntroductionIncidences of stroke are on the rise and approximately 80 million stroke survivors worldwide live with disabilities. Supportive care needs of stroke survivors are not adequately defined, and the assessment tools to help care service providers identify these needs are unclear. The overall aim of this scoping review will be to map the supportive care needs of stroke survivors against the Supportive Care Needs Framework.Methods and analysisThis scoping review will be conducted following Arksey and O’Malley’s methodological framework and Joanna Briggs Institute (JBI) updated methodological guidance for scoping review. This review will mainly use Arksey and O’Malley’s methodological framework as the basic framework. The review will also follow JBI’s updated methodological guidance for scoping reviews to optimise the review. For the search strategy, the three-step method recommended by the JBI will be used in the study. The review will be reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis extension for Scoping Reviews. Six English databases, including PubMed, CINAHL, Web of Science, Embase, Cochrane Library and PsycInfo, and four Chinese databases, including CNKI, Wanfang, VIP and China Biomedical Literature Database will be systematically searched from inception to the present. Studies published in English and Chinese will be included.Ethics and disseminationEthical approval is not required as this scoping review does not involve human participants. The findings shall be disseminated at scientific conferences and published in a peer-reviewed journal.
Spatial distribution of delayed initiation of antenatal care visits and associated factors among reproductive age women in Ethiopia: spatial and multilevel analysis of 2019 mini-demographic and health survey
Authors: Aragaw Fantu Mamo , Alem Adugnaw Zeleke , Asratie Melaku Hunie , Chilot Dagmawi , Belay Daniel Gashaneh 
Published: August 2023

ObjectivesThis study aimed to assess the spatial distribution, wealth-related inequality and determinants for delayed initiation of antenatal care (ANC) visits among reproductive-age women in Ethiopia.DesignCross-sectional study design.SettingEthiopia.ParticipantsA total of 2924 reproductive-age women who had given birth in the 5 years preceding the survey.Outcome measureDelayed initiation of ANC visits.ResultsThe magnitude of delayed initiation of ANC visits among reproductive-age women in Ethiopia was 62.63% (95% CI 60.86%, 64.37%). Women aged 35–49 (AOR=1.42; 95% CI 1.04, 1.94), being protestant religion followers (AOR=1.43; 95% CI 1.06, 1.94), being in higher wealth index (AOR=0.53; 95% CI 0.41, 0.69), living in rural residence (AOR=1.50; 95% CI 1.02, 2.19) and living in the metropolitan region (AOR=0.45; 95% CI 0.26, 0.77) were significantly associated with delayed initiation of ANC visit. Southern Nations Nationalities and Peoples Region (SNNPR), Somalia, Benishangul Gumuz, Southern Addis Ababa and Gambella regions were hot spot regions for delayed initiation of ANC visits. The SaTScan analysis result identified 107 primary clusters of delayed initiation of ANC visits located in regions of SNNPR, Gambella, Southern Addis Ababa, Eastern Oromia and Benishangul Gumuz.ConclusionsSignificant spatial clustering of delayed initiation of ANC visits was observed in Ethiopia. More than half of women had delayed initiation of ANC visits in Ethiopia. Women’s age, religion, wealth index, residence and region were significant predictors of delayed initiation of ANC visits. There is a disproportional pro-poor distribution of delayed initiation of ANC visits in Ethiopia. Therefore, interventions should be designed in the hot spot areas where delayed initiation of ANC visits was high to enhance the timely initiation of ANC visits.
Examination of gaze behaviour in social anxiety disorder using a virtual reality eye-tracking paradigm: protocol for a case–control study
Authors: Zeka Fatime , Clemmensen Lars , Arnfred Benjamin Thorup , Nordentoft Merete , Glenthøj Louise Birkedal 
Published: August 2023

IntroductionSocial anxiety disorder (SAD) has an early onset, a high lifetime prevalence, and may be a risk factor for developing other mental disorders. Gaze behaviour is considered an aberrant feature of SAD. Eye-tracking, a novel technology device, enables recording eye movements in real time, making it a direct and objective measure of gaze behaviour. Virtual reality (VR) is a promising tool for assessment and diagnostic purposes. Developing an objective screening tool based on examination of gaze behaviour in SAD may potentially aid early detection. The objective of this current study is, therefore to examine gaze behaviour in SAD utilising VR.Methods and analysisA case–control study design is employed in which a clinical sample of 29 individuals with SAD will be compared with a matched healthy control group of 29 individuals. In the VR-based eye-tracking paradigm, participants will be presented to stimuli consisting of high-res 360° 3D stereoscopic videos of three social-evaluative tasks designed to elicit social anxiety. The study will investigate between-group gaze behaviour differences during stimuli presentation.Ethics and disseminationThe study has been approved by the National Committee on Health Research Ethics for the Capital Region of Denmark (H-22041443). The study has been preregistered on OSF registries:https://doi.org/10.17605/OSF.IO/XCTAKAll participants will be provided with written and oral information. Informed consent is required for all the participants. Participation is voluntarily, and the participants can at any time terminate their participation without any consequences. Study results; positive, negative or inconclusive will be published in relevant scientific journals.
Methods for the involvement of people living with dementia in research focused on the built environment: a protocol for a scoping review
Authors: Fahsold Anne , Roes Martina , Holle Bernhard , Kuliga Saskia 
Published: August 2023

IntroductionThe positive influence of a well-designed built environment in dementia-specific care has been known for several years. Many studies focusing on the built environment have captured the perspectives of people living with dementia. However, it remains unclear to what degree and with which methods these individuals have been actively involved in research especially when attempting to understand their perspective. The planned scoping review aims to (1) synthesise methods and results from research about the built environment according to active involvement of people living with dementia and (2) describe facilitators and barriers to this active involvement to capture their perspectives in research.Methods and analysisWe will use four search strategies: (1) searches in academic databases MEDLINE via PubMed, CINAHL and APA PsycINFO via EBSCO, and Scopus; (2) grey literature searches via Google Scholar; (3) handsearches of non-academic environmental planning and design journals and (4) identifying other publications of key authors in the field. Additionally, backward and forward citation tracking will be performed via reference lists and Google Scholar, respectively. Relevant literature published between 2013 and 2023 will be identified for data extraction and synthesis. One researcher will perform each strategy. Title-abstract/full text-screening will be conducted using Covidence by two researchers. Results will be displayed in a table and through figures illustrating identified facilitators and barriers.Ethics and disseminationWe raised no ethical concerns for the planned scoping review. We will prepare the findings including the identified barriers with long-term care practitioners from our network to identify how changes in practical application methods can be addressed. This dialogue can serve as a basis for including people living with dementia to discuss highlighted barriers when researching their perspectives on the built environment. The scoping review results will be reported in both academic and non-academic journals and at academic conferences.