bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tolerance optimization of non-normal distribution characteristics for mechanical parts based on asymmetric cubic quality loss
Authors: Jin Kai , Liu Xintian , Liu Miao 
Published: March 2023

Abstract
Purpose: The error distribution of product quality is different, not all follow the normal distribution, and sometimes there is a non-normal distribution of the product. Therefore, the triangular distributions and trapezoidal distributions are investigated based on asymmetric cubic quality loss.
Design: Appropriate changes in the process mean value can effectively reduce the quality loss of the product. In order to study the optimization problem of the process mean with linear asymmetric quality loss, a mathematical model for calculating the expected quality loss considering the optimization of the process means is established.
Finding: The proposed model is solved, and the analytical solution of the optimal process mean is obtained. Moreover, a numerical model of inherent reliability that conforms to the triangular distribution is introduced. Due to the existence of measurement fluctuations, it will bring fluctuation loss. The measurement loss is improved. Finally, the objective function calculates the optimal tolerance is calculated with the minimum total cost. An example is given to illustrate the effectiveness of the model.
Evaluation of Shortest path of a Network Using Fuzzy Floyd Warshall Algorithm based on the uncertain environment
Authors: Raut Prasanta Kumar , Behera Siva Prasad , Broumi Said , Kar Pallab Kumar 
Published: March 2023

Abstract
Solving the shortest path problem (SPP) by the Floyd-Warshall algorithm (FWA) is often found in the literature. In this article, we propose a fuzzy Floyd-Warshall algorithm for resolving the SPP in fuzzy circumstances with fuzzy parameters. In reality, the problems encountered are inherently unknown, and one of the most important issues is evaluating the shortest paths in different networks. Here we apply the canonical operation procedure on the fuzzy trapezoidal number to improve the Floyd-Warshall method and name it the fuzzy (FWA). Furthermore, we compare our algorithm with the existing FWA and the rectangular algorithm, and also we take the node (vertices) as the crisp number and the edges (links) value as a trapezoidal fuzzy number to solve most of the shortest path issues on a given network. Finally, we cite one numerical example to demonstrate the validity of our algorithm.
An Inquire of Cost and Benefits of Structural Interventions: The Case of Medical Legal Partnerships for People Living with HIV in Philadelphia, PA
Authors: DelaCruz Juan J , Munoz-Laboy Miguel , Martinez Omar 
Published: March 2023

Abstract
The net benefits of medical legal partnerships (MLP), providers of legal service for HIV-infected individuals in clinical settings, is gaining importance in the economic evaluation literature. MLP are structural interventions designed to improve HIV care continuum outcomes beyond the epidemiological and behavioral approaches. This paper introduces a theoretical framework for the economic evaluation and impact of MLP as well as identifies the highest return on the program based on costs, resources, and risk involved. The intervention package includes training for all MLP care providers, a screening tool and protocol that is designed to identify PLWH patients’ health-harming legal needs, and provision of legal support through partnership with a local public interest law clinic. The intervention is conceptualized as a clustered-randomized small-scale trial in two HIV treatment services organizations in Philadelphia, PA. Our approach to addressing health-harming legal needs for PLWH is based on integrated care principles and co-location of services. A cost-benefit analysis will determine the program’s feasibility.
Trends in survival following dementia diagnosis: a multinational cohort study
Authors: Luo Hao , Koponen Marjaana , Roethlein Christoph , Becker Cornelia , Bell Simon , Beyene Kebede , Chai Yi , Chan Amy H. Y. , Chui Celine Sze Ling , Haenisch Britta , Hartikainen Sirpa , Hsu Amy T. , Ilomaki Jenni , Kim Ju Hwan , Knapp Martin , Kunkel Elizabeth , Lai Edward Chia-Cheng , Lau Kui Kai , Lau Wallis C.Y. , Lee Hyesung , Liao Tzu-Chi , Lum Terry Y.S. , Man Kenneth , Shin Ju-Young , Tolppanen Anna-Maija , Wong Gloria H.Y. , Wong Ian 
Published: March 2023

Abstract
This multinational cohort study examines the trends in relative mortality risk following dementia diagnosis in the UK, Germany, Finland, Canada (Ontario), New Zealand, South Korea, Taiwan, and Hong Kong. A common protocol was applied to population-based data of individuals aged 60+ with an incident dementia diagnosis recorded between 2000 and 2018. Data from 1,272,495 individuals showed that the standardised mortality ratios (SMRs) for dementia ranged from 1.27 (95% CI 1.27-1.28; UK) to 2.90 (2.87-2.93; New Zealand). Both adjusted SMRs and hazard ratios (HRs) estimated from Cox proportional hazard models declined consistently over the study period in the UK, Canada, South Korea, Taiwan and Hong Kong, which accounted for 84% of all participants. This study found a steady trend of decreasing risk of mortality in five out of eight databases, which signals the potential positive effect of dementia plans and associated policies and provides reference for future policy evaluation.
Uveitic Complications Associated with Smoking Status
Authors: Samalia Priya , Kang Grace , Sims Jo , Niederer Rachael 
Published: March 2023

Abstract
Background/Objectives: Smoking is a modifiable health risk factor that can worsen various health outcomes. The primary objective of this study was to determine the association between the development of uveitic complications and smoking status.
Subjects/Methods: This was a retrospective observational study consisting of 2 946 subjects with uveitis with documented smoking status from January 2008 to December 2020. Uveitic complications were examined in ex-smokers, current smokers and non-smokers.
Results: Current smokers accounted for 9.9% and ex-smokers for 15.5%. Māori and Pacific Peoples were over-represented in ex-smokers and current smokers (p<0.001). On univariate analysis, current smoking was associated with higher odds of posterior synechiae (OR = 1.452, p = 0.009). When controlled for age and gender, current smoking was still associated with higher odds of posterior synechiae (OR = 1.367, p = 0.031). When controlled for age, gender and ethnicity, posterior synechiae was no longer significantly associated with current smoking (OR = 1.272, p = 0.108). There was a tendancy towards a lower odds of occlusive vasculitis in current smokers when controlled for demographics, although this did not quite reach significance (OR 0.400, p=0.082).
Conclusion: Smoking may be an important factor in the development of some uveitic complications such as posterior synechiae. Ethnic disparities in smoking cessation need to be addressed in a culturally sensitive way and it is important for treating ophthalmologists to counsel patients on smoking cessation for their overall general health.
Network Meta-Analysis on the Mechanisms underlying Type 2 Diabetes Augmentation of COVID-19 Pathologies
Authors: Kim Ryan J. , Khan Mohammed A.S. , Khan Maryam , Chang Sulie L. 
Published: March 2023

Abstract
Coronavirus disease-2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. SARS-CoV-2 virus is internalized by surface receptors, e.g., angiotensin-converting enzyme-2 (ACE2). Clinical reports suggest that non-insulin dependent diabetes mellitus (DM-II) may enhance COVID-19. This study investigated how DM-II augments COVID-19 complications through molecular interactions with cytokines/chemokines, using QIAGEN Ingenuity Pathway Analysis (IPA) and CLC Genomics Workbench 22 (CLCG-22). RNA-sequencing of islet β-cell genomes through CLCG-22 (SRA SRP287500) were analyzed to identify differential expression of islet β-cell genes (Iβ-CG). IPA’s QIAGEN Knowledge Base (QKB) was also used to retrieve 88 total molecules shared between DM-II and SARS-CoV-2 infection to characterize and identify Iβ-CG, due to close association with DM-II. Molecules directly associated with ACE2 and cytokines/chemokines were also identified for their association with SARS-CoV-2 infection. Using IPA, 3 Iβ-CG in common with both diseases, SCL2A2, PPARγ, and CPLX8, were downregulated by DM-II. Their downregulation occurred due to increased activity of cytokines/chemokines and ACE2. Collectively, this network meta-analysis demonstrated that interaction of SARS-CoV-2 with ACE2 could primarily induce endothelial cell dysfunction. Identification of common molecules and signaling pathways between DM-II and SARS-CoV-2 infection in this study may lead to further discovery of therapeutic measures to simultaneously combat both diseases.
Irreversible atrophy in memory brain regions over 7 years is predicted by glycemic control in type 2 diabetes without cognitive decline
Authors: Canario Nadia , Crisóstomo Joana , Duarte João , Moreno Carolina , Quental Hugo , Gomes Leonor , Oliveira Francisco , Castelo-Branco Miguel 
Published: March 2023

Abstract
Memory-related impairments in type 2 diabetes maybe be mediated by insulin resistance and hyperglycemia. Previous cross-sectional studies have controversially suggested a relationship between metabolic control and a decrease in hippocampal volumes, but only longitudinal studies can test this hypothesis directly. We performed a longitudinal morphometric study to provide such a direct test of a possible role of higher levels of glycated hemoglobin (HbA1C) with long term brain structural integrity in key regions of the memory system – hippocampus, parahippocampal gyrus and fusiform gyrus. Grey matter volume was measured at two different times – baseline and after ~ 7 years. We found an association between higher initial levels of HbA1C and grey matter volume loss in all three core memory regions, even in the absence of cognitive decline. Importantly, these neural effects persisted in spite of the fact that patients had significantly improved their glicemic control. This suggests that early high levels of HbA1c are irreversibly associated with subsequent long-term atrophy in the medial temporal cortex and that early intensive management is critical.
Statistical Computational Analysis in Luxury hotels in the era of COVID-19 : The Cretan case
Authors: Asmargiannakis Petros , Galariotis Emilios , Zopounidis Constantin 
Published: March 2023

Abstract
The goal of this research is to identify the investment preferences of top managers and owners of four- and five-star hotels and the impact of the COVID-19 pandemic on their investment planning. The study examines various factors, including the individual characteristics of executives (such as gender, age group, education level, and position held in the hotel unit), and their perceptions of the pandemic's effects on their investment planning. To the best of our knowledge, this is the first attempt to capture the pandemic's impact on investment options, planning, and spending for luxury hotels. The study first conducted a structured questionnaire survey to record investment priorities under two distinct scenarios: one prior to the pandemic and another after the pandemic's spread and containment measures. Statistical tests were then used to compare the results between the two periods, revealing clear differences in investment choices among top executives and owners. Chi-square tests were also employed to examine the impact of individual characteristics on executives' perceptions of the pandemic's impact on their investment planning and their willingness to limit investment spending. Ordinal regressions were used to explore association further. The findings show that participants' age group was associated with their perception of the pandemic's negative impact on investment planning and their willingness to limit investment spending. Participants' position in the hotel unit partially explained their willingness to reduce investment resources during the pandemic. Therefore, the research highlights that the age of higher management in luxury hotels impacts the business's ability to adapt to the post-COVID-19 environment. The results also suggest that policy makers' public measures aimed at enhancing executives' willingness to invest during difficult periods should consider these factors.
Distributed Environment Online Monitoring System Based on SOA
Authors: Li Ru , Chen Shancheng 
Published: March 2023

Abstract
Environmental contamination caused by energy extraction and processing is a persistent issue, and China’s environmental monitoring of mines is becoming increasingly rigorous as the 14th Five-Year Plan moves forward. This study proposes a distributed environmental online monitoring system to realize intelligent environmental monitoring in open-pit mines. The collection terminal utilizes PM2.5, PM10, temperature, and noise sensors for data collection. The hardware design employs an STM32 microcontroller as the control core. The communication design uses GPRS and RS-485 communication technologies to transmit data, and the software architecture utilizes a modular approach for data cleaning, data analysis, and data mining to achieve early warning and environmental quality evaluation in mining zones. The distributed environmental online monitoring system is tested in a mine, and the test data show the feasibility and effectiveness of the system. Good results on intelligently monitoring the environmental quality of the mine site are obtained.
Preparation and viscoelasticity of a novel hydrophobic associating polymer with salt stimulation responsiveness by functional monomer modification for fracturing fuids
Authors: Lai Xiaojuan , Liu Guiru , Liu Yong , Dong Xinping , Liu Xiaoqing , Mukhtar Yasir , Wang Lei , Wen Xin , Lu Lijuan 
Published: March 2023

Abstract
In this study, a salt-resistant hydrophobic association polymer (PZDY) is synthesized by acrylamide, octadecyl dimethylallyl ammonium chloride and decane polyoxyethylene ether acrylate by aqueous polymerization. The infrared spectroscopy, fluorescence spectroscopy, scanning electron microscopy and other characterization methods were used to study its properties, and the rheological properties of PZDY solution is analyzed. The results showed that when concentration of NaCl is less than 5 wt% and CaCl2 is less than 1 wt%, the viscosity of 0.4 wt% PZDY increases with the increase of salt concentration. When the salt concentration continued to increase, the PZDY viscosity gradually decreased. Investigation of the rheological behavior showed that 0.6 wt% PZDY in 5 wt% NaCl and 1 wt% CaCl2 solution, could withstand a temperature up to 180 °C, after being sheared for 2500 s at 170 s−1, and its viscosity was greater than 50 mPa·s. Moreover, the viscosity of 0.6 wt% PZDY in 5 wt% NaCl increased from 104 to 205 mPa·s and the viscosity of 0.6 wt% PZDY in 1 wt% CaCl2 increased from 110 to 157 mPa·s, when at a shear rate of 170 s-1, at 180 ° C and the shear time was less than 500 s. Meanwhile, SEM results showed that salt addition enhanced the quasi-spatial network structure, with closer clustering of PZDY molecules in NaCl solution than in CaCl2 solution. The storage modulus (G′) and loss modulus (G") increased with the increase of PZDY concentration. Therefore, PZDY can be used to improve the heat and shear resistance of fracturing fluids and enhance oil recovery.
Prevalence and Intensity of Human Schistosomiasis in Selected Rural Communities of Mecha District and Bahir Dar town Administration, West Gojjam, Northwestern Ethiopia
Authors: Getu Asmamaw Abat 
Published: March 2023

Abstract
The study was conducted in Selected Rural Communities of Mecha District and Bahir Dar Town Administration, West Gojjam, Northwestern Ethiopia, to determine the prevalence and intensity of human schistosomiasis. A total of 490 stool and urine specimens were collected using stool cup and test tubes respectively. The overall prevalence and intensity of Schistosoma mansoni was 10.4% and 128.03 eggs per gram of stool (EPG) respectively. The prevalence of infection ranging from 7.8% in Wotet Abay Peasant Associations to 12.9% Kudmi Peasant Associations. The prevalence of Schistosoma mansoni infection among males and females was 13.2% and 7.5%, respectively, and the intensity of infection was 132.37 EPG and 120.42 EPG, respectively. The prevalence of Schistosoma mansoni infection among different age groups ranging from 3.9% in ≥ 30 years to 20.5% in 10–14 years whereas, the intensity of infection was ranging from 89.47 EPG in ≥ 30 years to 168.22 EPG in 10–14 years. It signifies the fact that the age groups 10–14 and 15–19 years are the highest risk groups. It is recommended that to control schistosomiasis in the areas should target at the youngest segment of the population.
Linkage and next generation sequencing (NGS) data in six large Danish families with dyslexia
Authors: Eiberg Hans , Hansen Lars 
Published: March 2023

Abstract
Dyslexia is a common learning disability exhibited as a delay in acquiring reading skills despite adequate intelligence, and reading single real words are impaired in many dyslexics. Reading disability or developmental dyslexia (DD) is a neurodevelopmental disorder affecting children globally, and the molecular mechanisms underlying it are largely underdetermined, while loci and susceptibility genes are suggested by genetic mapping in families or cohorts and by genome wide association studies (GWAS). To identify a possible genetic cause, we genotyped and performed genome wide linkage analysis employing the programs LIPED and SNP6-LINK of six multigenerational families with autosomal dominant inherited dyslexia. The linkage analyses resulted in informative haplotypes segregating with the dyslectic trait in all families and a LOD score of Z>4 at 13q12.3 and 19p13.3, and a LOD score of Z>3 at 15q23-q24.1, 18q11.21, and 21q22.3. The five mapped regions are supported by previous linkage or associations studies of dyslexia. Whole genome sequencing (WGS) of affected individuals in the six family’s revealed rare regulatory variants in the mapped regions.
Characteristics of broadleaved woody phytoliths and their preservation in soils in the mid-subtropical zone of China
Authors: Liu Lidan , Liu Hengyu , Liu Hongyan 
Published: March 2023

Abstract
Background and aims
Phytolith analysis is a promising tool for paleovegetation reconstruction. However, compared with grass phytoliths, there are few studies that have classified the phytoliths of trees. Therefore, reliable definitions of phytolith types in woody plants and studies of representative woody phytoliths in soils are needed to provide an improved basis for reliable phytolith-based vegetation reconstruction.
Methods
To explore the morphology of woody phytoliths and their preservation in soils, we described the phytolith morphology of 60 common broadleaved woody plants in the mid-subtropical zone of China, based initially on anatomical origin, and then on shape and finally on texture. We also for the first time established an index (R value) to explore the preservation of broadleaved phytoliths in soil in this region.
Results
We divided the phytoliths of broadleaved woody plants into 6 major types and 36 sub-types. The 6 major types are: epidermal phytoliths, silicified stomata, tracheid, favose phytoliths, hair, and others. We found some degree of correspondence between different phytolith types and the parent plants. Fagaceae, Lauraceae, Magnoliaceae, Rosaceae, Anacardiaceae and Euphorbiaceae could be clearly distinguished from other families based on phytoliths. Only eight types of broadleaved phytoliths were present in the soils. Elongate attenuate, elongate tenuous psilate, and blocky regulate were better preserved in soils than the other types (elongate attenuate entire, tabular sinuate, hair, sclereid, and favose phytoliths).
Conclusion
Our results provide an important basis for the further application of phytoliths in paleovegetation reconstruction.
The Pashto Corpus and Machine Learning Model for Automatic POS Tagging
Authors: Haq Ijazul , Qiu Weidong , Guo Jie , Peng Tang 
Published: March 2023

Abstract

In this study we developed a corpus of the low-resource language – Pashto. The corpus consists of 5 million words, labeled for explicit word-boundaries. And at the time of writing this paper, around 2 million of the words are tagged for Part-of-speech (POS) information. Pashto has no explicit word-delimiter like whitespace in English. The word-boundary markers added to the corpus are not only useful in this study for splitting the text into words, but can also be used in the development of a specialized word segmenter for Pashto. The process of POS tagging was carried out in several rounds where each Round has two sub phases, the automatic POS assignment and manual correction. A specialized web application is developed for manual correction and quality control. The tagset used for tagging is very concise and pragmatic that is developed on the guidelines compatible with the previous standard corpora. In the first Round, the baseline Lexicon-based approach was used for tagging a chunk of 230K word and then manually corrected. Using these tagged words as training data, a Machine Learning (ML) model was trained for tagging the remaining corpus. The purpose of incorporating ML was to improve the accuracy of automatic POS assignment, thus to speed-up the tagging process and reduce the manual effort. Tagging results of the final ML-based model are very satisfactory, which yields an accuracy of 99% and F1-score of 98%. Besides building an automatic POS tagger, the proposed corpus is aimed to be used in countless open research areas in Pashto NLP such as homographs disambiguation, NER, word segmentation, text proofing, constituency and dependency parsing and language modeling etc.
Examination the effect of Jervin purified from the Veratrum album on changes in testicular tissue of varicocele-induced rats
Authors: YİĞİT Serdar , BINGÖL Seyit ALI , YAYLA Muhammed , ATALAY Fadime DUMLU , EYERCI Nilnur , AYDIN Tuba , KACI Fatma Necmiye 
Published: March 2023

Abstract
In this study, it was aimed to investigate the effects of jervine, which was isolated from Veratrum album, on testicular tissue obtained from induced varicocele rats by using histological, immunohistochemical, biochemical and molecular techniques. In this experimental study, 40 male Sprague Dawley rats of 8-week-old with an average weight of 180–200 g were used. Rats were randomly divided into 6 groups; varicocele, healthy + jervine (10 mg/kg), varicocele + jervine (5 mg/kg) and varicocele + jervine (10 mg/kg), control, sham. After the left testes were dissected and excised, tissues were divided into three parts for histological, biochemical and Real-Time PCR examinations. It was observed that seminiferous tubules were normal in the control, sham and healthy + jervine (10 mg/kg) groups but it was found that seminiferous tubules were destroyed in the varicocele and varicocele + jervine groups. TNF-α immunoreactivity was stronger in the varicocele group than that of others. It was found that SOD activity was decreased and CAT activity was raised in varicocele group matched to the control group. TNF and p53 gene expression were downregulated due to the effects of jervine. In summary, we conclude that jervine promotes sperm morphology and contributes to preventing varicocele-induced damage by reducing TNF-α and p53 levels in experimental varicocele rats.