bluuebunny/crossref_metadata_2025_split huggingface dataset:
Surveillance cardiopulmonary exercise testing can risk-stratify childhood cancer survivors: who are at risk for long-term cardiovascular complications and why?
Authors: Tsuda Takeshi , Davidow Kimberly , D’Aloisio Gina , Quillen Joanne 
Published: February 2023

Abstract
Background. Asymptomatic childhood cancer survivors (CCS) frequently show decreased exercise performance. Poor exercise performance may indicate impaired future cardiovascular health.
Methods. Cardiopulmonary exercise testing (CPET) was performed in asymptomatic off-treatment CCS (age ≥10 years). Those excluded were children with body mass index (BMI) ≥ 30. Patients were divided into Good and Poor performance groups by their peak oxygen consumption (pVO2*) at 35 and 25 ml/kg/min in males and females, respectively. * denotes weight-indexed values.
Results. Thirty-eight males (19 Good, 19 Poor) and 41 females (25 Good, 16 Poor) were studied. Total anthracycline dosage was comparable among 4 groups. The BMI, although normal, was significantly higher in Poor groups. Peak work rate (pWR*), pVO2*, peak oxygen pulse (pOP*), and ventilatory anaerobic threshold (VAT*) were significantly lower, whereas heart rate (HR) increase by WR* (DHR/DWR*) and peak respiratory exchange ratio (pRER) was significantly higher in Poor groups. Simultaneously plotting of weight & pVO2 and DHR/DWR* & pOP* revealed a distinct difference between the Good and Poor groups in both sexes, suggesting decreased skeletal muscle mass and decreased stroke volume reserve, respectively, in Poor CCS. Decreased endurance at peak exercise was noted in Poor groups by simultaneously plotting DVO2*/DHR and pOP*. Ventilatory efficiency was mildly diminished in the Poor groups.
Conclusions. Decreased stroke volume reserve, decreased skeletal muscle mass, impaired muscle energy metabolism, decreased ventilatory efficiency, and increased BMI characterized Poor CCS in both sexes. This unique combined CPET analysis provides useful clinical biomarkers to screen subclinical cardiovascular abnormality in CCS.
A patient with Situs Inversus Totalis who underwent Laparoscopic Sleeve Gastrectomy: a case report
Authors: Corzo Héctor Joaquín Pérez , Sotelo José Sergio Verboonen , Salas Roberto Esau Salgado , Manzano Jeffry Romero , Barba José Aldo Guzmán , Mejía Francisco Javier Quero , Fong Jhonattan Arturo Barriga , Estrada Isaac Esparza 
Published: February 2023

Abstract

Introduction Obesity is associated with several preventable health issues, such as diabetes mellitus and hypertension. Bariatric surgery has shown potential treating obesity. Laparoscopic sleeve gastrectomy (LSG) is one of the several bariatric surgical techniques that is gaining popularity as primary bariatric surgery. Situs Inversus Totalis (SIT) is an uncommon hereditary abnormality that can make laparoscopic surgery challenging due to the anatomy's mirror-image aspect.
Case report We present the case of a 54-year-old female, BMI was 54.36 kg/m2. She was diagnosed with Situs Inversus Totalis, with no other known diseases, drug intake, or allergies. We performed a conventional laparoscopic gastric sleeve modifying the original trocar ports positions like a mirror to match the anatomy.
Conclusion Laparoscopic gastric sleeve is a safe and effective procedure for patients with Situs Inversus Totalis. Preoperative diagnosis can help lower the risk of complications by having a proper surgical plan.
Backwashing of granular media filters and membranes for water treatment: a review
Authors: Turan Mustafa 
Published: February 2023

AbstractFilter backwashing is a supplemental part of a drinking water treatment (DWT) facility to wash the filter bed at regular intervals using water or air scour/water by fluidizing the filter bed. Deposited material induces clogging the filter pores and enhances head loss in the bed. Biofiltration has been extensively utilized to decrease organic matter and manage the occurrence of disinfection by-products within drinking water sources. Biological rapid sand filters are frequently utilized to eliminate ammonium from groundwater provinces with the purpose of meeting drinking water requirements. Biological activated carbon (BAC) filters need to be backwashed to wash and enhance the treatment capability by detaching both restrained materials and residual biomass. The reclamation of activated carbon-used backwash water (UBW) was managed by exercising an ultrafiltration (UF) procedure.
The Emerging Landscape of Natural Small-molecule Therapeutics for
Huntington’s Disease
Authors: Bhat Shahnawaz Ali , Ahamad Shakir , Dar Nawab John , Siddique Yasir Hassan , Nazir Aamir 
Published: February 2023

Abstract:
Huntington’s disease (HD) is a rare and fatal neurodegenerative disorder with no disease modifying therapeutics. HD is characterized by extensive neuronal loss and is caused by the inherited expansion of the huntingtin (HTT) gene that encodes a toxic mutant HTT (mHTT) protein having expanded polyglutamine (polyQ) residues. Current HD therapeutics only offer symptomatic relief. Infact, Food and Drug Administration (FDA) approved two synthetic small-molecule VMAT2 inhibi-tors, tetrabenazine (1) and deutetrabenazine (2), for managing HD chorea and various other diseases in clinical trials. Therefore, the landscape of drug discovery programs for HD is evolving to discover disease-modifying HD therapeutics. Likewise, numerous natural products are being evaluated at different stages of clinical development and have shown the potential to ameliorate HD pathology. The inherent anti-inflammatory and antioxidant properties of natural products mitigate the mHTT-induced oxidative stress and neuroinflammation, improve mitochondrial functions, and augment the anti-apoptotic and pro-autophagic mechanisms for increased survival of neurons in HD. In this review, we have discussed HD pathogenesis and summarized the anti-HD clinical and pre-clinical natural products, focusing on their therapeutic effects and neuroprotective mechanisms.
Decision Support Model for Contractor Selection
Authors: Mergawy Reem T. , Hosny Hossam E. , Abdelazeem Abdelazeem S. 
Published: February 2023

Introduction:
The construction and infrastructure industries in Egypt have recently experienced huge growth, which of course requires methodical planning, full feasibility studies, and wise selections of project executors' teams, including engineering design offices, management agencies, and contracting firms. Consequently, to guarantee achieving the predetermined project designs and objectives, a careful assessment of the incorporating contractor company must be carried out.

Problem Statement:
Improper contractor selection leads to several problems throughout the project delivery phase, including inadequate quality and delays in the expected project time, which results in cost overruns. Rather, it also sometimes results in suspending the project and failing to complete it. Moreover, in most public and governmental projects, in accordance with law 182/2018, the responsible employee is forced to choose the lowest-priced bid regardless of any other considerations, only passing the project's minimum technical score defined by the appropriate authority, and this is illogical and must be reconsidered.

Methodology:
In order to find a solution to these problems, the following steps were taken in this paper: (1) Forty-eight factors affecting contractor selection were identified through surveying; (2) the seven most important factors were selected based on the fuzzy Delphi technique (FDT); and (3) competitive contractors were prioritised at the pre-bidding stage for the construction project by utilising the analytic hierarchy process (AHP) combined with the analytic network process (ANP).

Results:
Seven of the forty-eight factors were selected using the fuzzy Delphi technique, and to calculate their relative weights, AHP and ANP were combined to obtain the most important variables affecting contractor selection. Next, a model user interface for picking contractors was developed to make it easier for project owners and managers to apply. To fully understand how the model functions, a realistic case study involving four bidders competing for the contract has been included.

Conclusion:
Since government agencies oblige decision-makers to select the lowest-priced bidder, this model can be used during the tendering process's prequalification stage to ensure that all potential contractors are qualified while including the most influential criteria from the Egyptian construction market's perspective.
"The Important Impact of Health Behaviors on Negative Emotions of China College Students：A longitudinal study" (Preprint)
Authors: Tao YunFei , Wu Jin Long , Peng Li , Zheng KangYong , Huang Li , Liu Hao Wei , Shi Qiu qiong , Tian Hao Dong 
Published: February 2023

BACKGROUND

The COVID-19 outbreak has gradually become more normal. College students, one of the groups most affected by the epidemic, often suffer from varying degrees of psychological problems. The prevention and improvement of college students' psychological problems are particularly important for both individuals and society.

OBJECTIVE

The purpose of this study was to explore (1) the changes in college students’ negative emotions during the epidemic containment period, (2) the correlation between negative emotions and healthy behaviors, and (3) the main factors that can affect negative emotions in healthy behaviors.

METHODS

A total of 5872 Chinese college students was selected as subjects in this study. The negative emotion Scale (DASS-21) and the health Behavior Scale (HPLP-Ⅱ) were used to investigate the level of negative emotions and health behaviors on November 12, 2021, and June 17, 2022, respectively.

RESULTS

The results obtained in this study have shown the significant differences between negative emotions and health behavior scores at two-time points. And there was a negative correlation between negative emotions and health behaviors. The former negative emotions can predict later health behaviors, and the former health behaviors can predict later negative emotions. In addition, stress management, spiritual growth, and responsibility for health in health behaviors have a strong correlation with negative emotions, which are the main influencing factors to reduce negative emotions in college students.

CONCLUSIONS

The results of this study suggest that the psychological problems of college students have become particularly serious under the dual influence of campus lockdown and academic pressure during the epidemic. Positive health behaviors may be beneficial to reduce the negative emotions of college students. Therefore, we should pay more attention to their mental health problems by reminding and guiding them to adopt a healthy lifestyle, to prevent and improve the mental health problems that they may have been accumulating, and for supporting them when necessary.
Engagement in Free Open Access Medical Education by US Nephrology Fellows
Authors: Larsen Dana M. , Boscardin Christy K. , Sparks Matthew A. 
Published: February 2023

Background
As free open access medical education (FOAMed) use increases, it is important to characterize how and why learners are using this educational material in nephrology. We describe the frequency, purpose, and type of FOAMed usage across US nephrology fellows.

Methods
In this cross-sectional survey, items were emailed to all US adult and pediatric nephrology fellows via the American Society of Nephrology (ASN) Fellow Survey in May 2022. The eight-item survey, developed to measure FOAMed engagement, had previously undergone instrument validation. The results were analyzed by descriptive statistics.

Results
In total, 43% (359/842) adult nephrology fellows and 51% (45/88) pediatric nephrology fellows completed the survey. Seventy-four percent (300/404) of fellows reported using FOAMed, and 72% (215/300) started using FOAMed within the past 2 years. Of FOAMed users, 41% (122/300) reported viewing FOAMed and 33% (99/300) reported applying knowledge gained from these resources daily or weekly. Common purposes for FOAMed engagement included searching Twitter to learn about others' opinions in the field (43%; 130/300), reading blogs to answer clinical questions (35%; 105/300), and listening to podcasts for the most up-to-date information (39%; 116/300). Compared with traditional educational resources, fellows preferred using FOAMed for staying up to date on nephrology topics (75%) and answering clinical questions (37%). Among all fellows, the greatest barriers to FOAMed use were unfamiliarity with FOAMed (27%; 111/404), validity concerns (22%; 90/404), and a lack of a local community of FOAMed users (22%; 87/404).

Conclusions
Seventy-four percent of nephrology fellows used FOAMed resources in a variety of ways, and of them, 33% of fellows clinically applied knowledge gained from these resources. Reasons for engaging with FOAMed varied across resources.
En otro margen: Miguel Brascó
Authors: Viú Adagio Julieta 
Published: February 2023

En un contexto artístico al menos adverso a la representación del consumo y el ocio, el argentino Miguel Brascó, habitué de bodegas y restaurantes, escribió gran cantidad de crónicas sobre el escabio y el morfi orientadas al mundo gourmet. Este escritor bautizado “periodista de vinos” (que realizaba charlas en viñedos, participaba de programas televisivos sobre cocina y dirigía revistas gastronómicas) construyó una imagen de cronista bon vivant atípica para el género a la vez que inauguró una escritura sin prejuicios sobre temas desatendidos. En este artículo, se aborda la centralidad del placer definitoria de su estética que ilumina una zona oculta de la crónica latinoamericana forjada a partir de un autor que en su relación con el mundo antepuso el disfrute. Estos textos de fines del siglo xx fueron construidos a partir del saber de la boca o, en términos de Michel Onfray, la sapiencia gustativa: un placer de la lengua que, en la prosa de Miguel Brascó, deviene placer del lenguaje. De allí la originalidad de este artículo de abordar a un autor al margen del canon con una posición excéntrica respecto de los temas y modos de representación hegemónicos.
Computational modelling and experimental study of the thermal transport characteristics of graphene nanoribbons
Authors: Chen Junjie 
Published: February 2023

Graphene is a two-dimensional form of crystalline carbon, either a
single layer of carbon atoms forming a hexagonal lattice or several
coupled layers of this honeycomb structure. Graphene is a parent form of
all graphitic structures of carbon. However, the field of graphene
science and technology is relatively new. Progress depends not only on
the basic science but also on the development of new ways to produce
graphene on an industrial scale. The present study is focused primarily
upon the thermal transport characteristics of graphene nanoribbons. The
thermal transport characteristics of graphene nanoribbons are studied
using molecular dynamics simulations and by experimental measurements. A
specific heat flux is imposed through the graphene nanoribbon. The
graphene nanoribbon is considered as a single layer of carbon atoms with
each atom bound to three neighbors in a honeycomb structure. The thermal
conductivity is determined from the temperature gradient obtained and
the heat flux imposed. The present study aims to provide a fundamental
understanding of the thermal transport properties of graphene
nanoribbons. Particular emphasis is placed upon the effect of various
factors on the thermal conductivity of graphene nanoribbons under
different conditions. the results indicate that the mean free path of
phonons depends on the nanoribbon structure and dimensions. The thermal
conductivity increases with increasing nanoribbon length. Graphene
nanoribbons offer tremendous promise for providing enhanced transport
performance. Graphene undergoes a metallic-to-semiconducting transition
as the nanoribbon width decreases. The properties of graphene
nanoribbons are highly dependent on their width and edge structure. The
graphene nanoribbons can be derived through the longitudinal splitting
of carbon nanotubes.
Keywords: Graphene nanoribbons; Graphitic structures; Carbon
nanotubes; Carbon nanofibers; Thermal properties; Thermal conductivity
Dampak Pembelajaran Daring Terhadap Siswa (Studi Kasus Orang Tua Berprofesi Petani dan PNS)
Authors: Ni Luh Santikawati  , Putu Nanci Riastini  , Gede Nugraha Sudarsana  
Published: February 2023

Pembelajaran online memiliki dampak berbeda, sesuai dengan profesi orang tua siswa. Tujuan penelitian ini yaitu menganalisis dampak pembelajaran daring terhadap siswa (studi kasus orang tua berprofesi petani dan PNS). Jenis penelitian ini yaitu sequential explanatory. Pendekatan yang digunakan dalam penelitian ini adalah mixed method. Sumber data primer pada penelitian ini diperoleh dari narasumber (orangtua, siswa, dan guru) dan sumber data sekunder dari dokumentasi selama penelitian. Populasi penelitian ini yaitu orang tua yang memiliki profesi sebagai petani dan PNS beserta anaknya. Teknik yang digunakan untuk menganalisis data yaitu analisis kuantitatif dan kualitatif. Hasil penelitian yaitu dampak pembelajaran daring terhadap siswa yang orang tuanya petani adalah dari berdampak hingga sangat berdampak seperti penurunan nilai, kegelisahan belajar, penurunan komunikasi, dan ketinggalanbelajar. Dampak pembelajaran daring terhadap siswa yang orang tuanya PNS adalah dari kurang berdampak hingga berdampak sedang seperti kesetabilan nilai karena fasilitas memadai, kesenangan belajar, keeratan hubungan orang tua dan anak.
Diagnosis, treatment, and outcome of four dogs with alveolar echinococcosis in the northwestern United States
Authors: Williams Laura B. A. , Walzthoni Natasha 
Published: February 2023

Abstract

OBJECTIVE
To describe the clinical disease, diagnostic findings, medical management, and outcome in dogs with alveolar echinococcosis (AE).

ANIMALS
4 dogs with naturally occurring AE.

PROCEDURES
Medical records were retrospectively reviewed from 2020 to 2022 to identify dogs diagnosed with AE. Signalment, case history, clinical signs, imaging and pathological laboratory findings, treatment, and clinical outcome were reported.

RESULTS
All dogs developed systemic clinical illness and weight loss. Abdominal ultrasonography revealed multifocal to coalescent cystic masses of variable size distributed throughout the liver in all cases. Evaluation of aspirated hepatic cyst contents included membranous parasite structures and calcareous corpuscles. Echinococcus multilocularis was confirmed via PCR from hepatic cyst fluid in 3 of 4 cases. Treatment included systemic benzimidazole and praziquantel administration, 1 or more instances of ultrasound-guided cyst drainage in all cases, with ethanol ablation (percutaneous aspiration-injection-reaspiration) in 2 cases, and surgical resection in 1 case. Two of 4 dogs were euthanized within 5 months of diagnosis. One of these dogs was necropsied and had nearly complete obliteration of the hepatic parenchyma by multilocular cystic masses. One dog is still alive, and 1 dog has been lost to follow-up.

CLINICAL RELEVANCE
This series of cases highlighted the diagnostic findings and therapeutic intervention in 4 dogs with AE. This was the first report of medical management incorporating the percutaneous aspiration-injection-reaspiration method used in humans. Reports of canine AE are rare in the US, so this series serves to help raise awareness of hepatic AE in the northwestern US.
Water Supply of the Ukrainian Polesie Ecoregion Drained Areas in Modern Anthropogenic Climate Changes
Authors: Kuzmych Lyudmyla , Furmanets Oleh , Usatyi Serhii , Kozytskyi Oleh , Mozol Nazar , Kuzmych Anna , Polishchuk Vitalii , Voropai Halyna 
Published: February 2023

Abstract
The paper focuses on research on improving the water supply of drainage systems of humid areas in the context of anthropogenic climate change. The aim of the research is to elaborate on the ways for increasing the available water supply of drainage systems and restoring active water regulation on reclaimed lands in a changing climate. Reclaimed lands are the main factor of sustainable agricultural production in Ukraine and guarantors of its stability. The area of drained lands in Ukraine is about 3.2 million hectares, including 2.3 million hectares drained with the help of closed drainage; in an area of 1.3 million hectares a two-way regulation of the soil water regime is carried out. An increase in air temperature and uneven distribution of precipitation, which has a torrential, local character in the warm period, do not allow for the e ective accumulation of moisture. The recurrence of droughts in di erent justified climatic zones of Ukraine has increased by 20–40%, which prevents sustainable agricultural production in the zone of su cient atmospheric moisture, in particular the Polesie Ecoregion. In this paper, the analysis of water consumption of reclaimed lands in the Polesie Ecoregion of Ukraine is carried out, on the examples of the drainage system “Maryanivka” and the calculation of the water supply for the corn and winter wheat.
Prevalensi Infeksi Cacing Nematoda Gastrointestinal pada Ayam Petelur di Desa Peninjoan, Kecamatan Tembuku, Kabupaten Bangli, Bali
Authors: Belo Agostinho Moreira , Suratma I Nyoman Adi , Oka Ida Bagus Made 
Published: February 2023

Nematoda termasuk kelompok parasit cacing yang penting menginfeksi unggas sehubungan dengan banyaknya spesies dan kerusakan yang ditimbulkan. Cacing nematoda yang umum menginfeksi saluran pencernaan ayam diantaranya adalah Capilaria spp, Tetrameres spp, Aquaria spp, Ascaridia galli, Strongyloides avium, Trichostrongylus sp dan Heterakis gallinarum. Faktor risiko yang berpengaruh terhadap kejadian infeksi parasit dipengaruhi oleh; hospes, parasit dan lingkungan. Faktor hospes yang paling umum berpengaruh, terhadap kejadian infeksi diantaranya: jenis ayam, umur, jenis kelamin, sedangkan faktor parasit yang mempengaruhi terjadi infeksi diantaranya: cara penularan, viabilitas (daya tahan hidup), patogenitas dan imunogenitas, serta faktor lingkungan yang berpengaruh terutama : cuaca, sanitasi kandang dan kelembaban. Tujuan dari penelitian ini adalah untuk mengetahui prevalensi infeksi cacing nematoda grasterointestinal pada ayam petelur serta hubungannya dengan umur ayam di Desa Peninjoan, Kecamatan Tembuku, Kabupaten Bangli, Bali. Objek penelitian yang digunakan adalah feses dari ayam petelur yang diambil secara lagsung sebanyak 240 sampel. Metode pemeriksaan yang digunakan adalah secara kualitatif dengan menggunakan metode apung. Hasil penelitian didapatkan bahwa prevalensi infeksi cacing nematoda gastrointestinal pada ayam petelur sebesar 9,17 %. Hasil analisis menunjukkan tidak ada hubungan antara umur ayam petelur dengan prevalensi infeksi cacing nematoda gastrointestinal pada ayam petelur yang dipelihara di Desa Peninjoan, Kecamatan Tembuku, Kabupaten Bangli, Bali.