bluuebunny/crossref_metadata_2025_split huggingface dataset:
Psychosocial factors associated with health behaviors in pregnant women of advanced maternal age in Korea
Authors: Jeon Songi , Noh Wonjung 
Published: June 2023

ObjectivesTo determine the association between psychosocial factors and health-promoting and health-impairing behaviors in pregnant women of advanced maternal age (AMA) in Korea.DesignA cross-sectional survey study.SettingOnline survey.SamplesA total of 217 pregnant women aged 35 and older agreed to participate in the study, with 207 participants completing the self-report questionnaires.MethodsWe collected self-reported data on demographic, obstetric, and psychosocial factors and prenatal health behaviors using standardized measures. We conducted a descriptive analysis of the collected data and a linear regression to identify significant associations with health-promoting and health-impairing behaviors.ResultsWe found that maternal–fetal attachment (β = 0.43, p &lt; 0.001) and “social atmosphere” of pregnancy stress (β = 0.13, p = 0.047) were positively associated with prenatal health-promoting behaviors. We found that artificial conception (β =-0.16, p = 0.011) was negatively associated with prenatal health-impairing behaviors and that multiparity (β = 0.23, p = 0.001) and “maternal role” of pregnancy stress (β = 0.27, p = 0.003) positively associated with prenatal health-impairing behaviors.ConclusionHealth-impairing behaviors of pregnant AMA women need assessment and the importance of health-promoting behaviors for maternal and infant health need reinforcing. We recommend pregnancy stress assessments at prenatal checkups and stress relief interventions that consider cultural differences and contexts rather than standardized interventions.
50 years of the first ethics commission in Germany: the Ulm Ethics Commission in an international perspective
Authors: Steger Florian , Kosenko Oxana 
Published: June 2023

BackgroundThe creation of the legal framework to recognize rights of patients and participants in clinical trials began in Germany in the 19th century. However, the ethical review of medical research in terms of the protection of rights and welfare of human subjects has only become a widespread practice since the establishment of ethics commissions. The first ethics commissions emerged at the universities under the influence of the German Research Foundation. The widespread establishment of ethics commissions began in the Federal Republic of Germany in 1979, after the adoption of the recommendation of the German Medical Association for the establishment of ethics commissions.Materials and methodsWe analyzed unpublished archival documentation of the Ethics Commission of the University of Ulm and evaluated it based on a thorough review of research works on the history of international and German ethics commissions. For the examination of the sources, we implemented the historical-critical method.ResultsThe first ethics commission in Germany was set up at the University of Ulm in 1971/72. The reason for that was that the German Research Foundation required grant applications for medical research involving human subjects to be reviewed by an ethics commission. Initially the commission was created at the Center for Internal Medicine and Pediatrics, its authority grew over time until in 1995 it became the central Ethics Commission for the entire University of Ulm. Before the adoption of the Tokyo revision of the Declaration of Helsinki in 1975, the Ulm Ethics Commission developed its own guidelines for the conduct of scientific investigations on humans based on international ethical principles.ConclusionThe Ethics Commission of the University of Ulm must have been established between July 1971 and February 1972. The German Research Foundation played a decisive role in the establishment of the first ethics commissions in Germany. The Universities had to create ethics commissions in order to be able to obtain additional funds from the Foundation for their research. Thus, the Foundation initiated the institutionalization of the ethics commissions in the early 1970s. The functions and composition of the Ulm Ethics Commission were similar to other initial ethics commissions of the time.
The prevalence, incidence, and persistence of self-reported visual impairment among Chinese population with diabetes mellitus: evaluation from a nationally representative survey, 2015–2018
Authors: Zhou Yifan , Wei Jin , Wang Ning , Chen Yisheng , Fang Cheng , Zhou Minwen , Zhou Xinrong , Luo Jianfeng , Wang Xiaodong , Peng Qing 
Published: June 2023

AimsOur aim was to investigate the prevalence, incidence, and persistence of visual impairment (VI) and their correlates among the Chinese population with diabetes mellitus (DM) over 3 years.Materials and methodsThe China Health and Retirement Longitudinal Survey is the first nationally representative longitudinal survey of the Chinese population. A cross-sectional analysis of prevalent VI in 2015 consisted of 2,173 participants with DM. A longitudinal observation of incident and persistent VI consisted of 1,633 participants from 2015 to 2018. Risk factors of VI were identified via univariate and multivariate logistic regression analyses.ResultsAmong our study population with DM, 11.8% reported VI in 2015, 4.5% had persistent VI from 2015 to 2018, and 8.9% developed VI in 2018. Factors identified to be correlated to VI (p &lt; 0.05) were older age, being a woman, lower educational attainment, living in a rural area, application of DM medication and non-pharmacological treatment, receiving DM-related tests, use of spectacles, and poorer health status.ConclusionThis most recent national data provides a baseline for future public health initiatives on VI among the Chinese population with DM. With multiple risk factors identified, these could provide concurrent targets for various public health strategies and interventions with the aim of reducing the burden of VI among the population with DM in China.
Elite cassava clones (Manihot esculenta) grown in Zambia: effects of drying techniques on their chemical, functional, and pasting properties
Authors: Alamu Emmanuel Oladeji , Manda Noah , Ntawuruhunga Pheneas , Abass Adebayo , Maziya-Dixon Busie 
Published: June 2023

IntroductionCassava (Manihot esculanta) is becoming an important crop in most developing countries, especially Zambia. However, cassava roots deteriorate quickly after harvest, producing flour or chips of sub-optimal quality. Hence the evaluation of processing procedures to extend the product's shelf-life cannot be overemphasized. This study investigated the effects of different drying methods on the chemical, functional and pasting properties of selected advanced cassava clones grown in Zambia.MethodsFresh Roots of the seven cassava clones (harvested 12 months after planting) were sampled, peeled, washed and dried using the three drying methods (sun-drying, oven-drying and freeze-drying). The flour samples from these drying methods were analyzed using standard laboratory methods for primary chemical, functional and pasting properties. The data generated were statistically analyzed for descriptive, analysis of variance (ANOVA), and the means were separated at p &lt; 0.05.Results and discussionThe clone and drying method had significant effects (p &lt; 0.001) on most chemical, functional and pasting properties. Clone 00/0093 had consistently lower ΔE* values for each drying method than other clones. The overall mean of total color difference (ΔE*) across the genotypes revealed the ranking ΔE* for drying techniques in the order of oven &gt; sun &gt; freeze drying. Generally, the highest sugar content was recorded for the freeze-dried samples. Similarly, the total starch content was higher in the sun-dried samples of six out of the seven samples than in the oven-dried samples. The functional properties ranged from 31.29–61.04%, 2.31–5.41%, 119.68–206.78% and 54–70 for solubility, swelling power, water absorption capacity and dispersibility, respectively.ConclusionIn conclusion, the clonal effect of the cassava and drying method significantly affected the cassava flours' color, chemical, functional, and pasting properties.
Assessment of pesticide residues in vegetables produced in central and eastern Ethiopia
Authors: Dinede Getachew , Bihon Wubetu , Gazu Lina , Foukmeniok Mbokou Serge , Girma Sisay , Srinivasan Ramasamy , Roothaert Ralph , Grace Delia , Gashaw Habtamu , Knight-Jones Theodore J. D. 
Published: June 2023

BackgroundIn Ethiopia, pesticides are widely used in vegetable production. However, if used incorrectly they may harm consumers of vegetables contaminated with pesticide residues, as well as producers handling the pesticides and lead to ecological damage. We performed a cross-sectional survey to assess pesticide residues in vegetables produced in central and eastern Ethiopia.MethodsA total of 232 vegetable samples (91 tomatoes, 106 cabbages and 35 Swiss chard) were collected from fields and retail markets, and were screened for 35 pesticides (16 organochlorine, 11 organophosphate, 3 pyrethroids, 2 carbamates and 3 other agrochemicals) using GC–MS analysis.ResultsPesticides residues were detected in 60% of Swiss chard, 47% of cabbage and 45% of tomato samples. Two or more pesticides were detected in 20% of cabbages, 13% of tomatoes and over half of Swiss chard samples. Bendiocarb, diazinon, endrin, piperonyl butoxide, profenofos and propargite were detected, but only diazinon, propargite and profenofos had residual values above EU Maximum Residue Level (MRL), with diazinon commonly detected at relatively high levels. About 15% of the total analyzed samples, 10% of cabbages and tomatoes, and nearly half of Swiss chard samples had pesticide concentration exceeding EU MRL. However, none of the tested samples had residues exceeding Codex Alimentarius Commission (Codex) MRLs.ConclusionThis study showed widespread contamination of vegetables with pesticides, mainly organophosphates. We recommend monitoring and regulation of pesticides usage, with promotion of good agricultural practices.
Impact of cell-free supernatant of lactic acid bacteria on Staphylococcus aureus biofilm and its metabolites
Authors: Mao Yanni , Wang Yuxia , Luo Xiaofeng , Chen Xiaohui , Wang Guiqin 
Published: June 2023

IntroductionA safe bio-preservative agent, lactic acid bacteria (LAB) can inhibit the growth of pathogenic bacteria and spoilage organisms. Its cell-free supernatant (LAB-CFS), which is rich in bioactive compounds, is what makes LAB antibacterial work.MethodsThis study focused on the changes in biofilm activity and related metabolic pathways of S. aureus treated with lactic acid bacteria planktonic CFS (LAB-pk-CFS) and biofilm state (LAB-bf-CFS).ResultsThe findings demonstrated that the LAB-CFS treatment considerably slowed Staphylococcus aureus (S. aureus) growth and prevented it from forming biofilms. Additionally, it inhibits the physiological traits of the S. aureus biofilm, including hydrophobicity, motility, eDNA, and PIA associated to the biofilm. The metabolites of S. aureus biofilm treated with LAB-CFS were greater in the LAB-bf-CFS than they were in the LAB-pk-CFS, according to metabolomics studies. Important metabolic pathways such amino acids and carbohydrates metabolism were among the most noticeably altered metabolic pathways.DiscussionThese findings show that LAB-CFS has a strong potential to combat S. aureus infections.
Sleep Problems Associate With Multimorbidity: A Systematic Review and Meta-analysis
Authors: Zhou Yaguan , Jin Yichen , Zhu Yi , Fang Weiwei , Dai Xiaochen , Lim Carmen , Mishra Shiva Raj , Song Peige , Xu Xiaolin 
Published: June 2023

Objectives: To summarize the evidence on the association between sleep problems and multimorbidity.Methods: Six electronic databases (PubMed, Web of Science, Embase, China National Knowledge Infrastructure, VIP, and Wan fang) were searched to identify observational studies on the association between sleep problems and multimorbidity. A random-effects model was used to estimate the pooled odds ratios (ORs) and 95% confidence intervals for multimorbidity.Results: A total of 17 observational studies of 133,575 participants were included. Sleep problems included abnormal sleep duration, insomnia, snoring, poor sleep quality, obstructive sleep apnea (OSA) and restless legs syndrome (RLS). The pooled ORs (95% CIs) for multimorbidity were 1.49 (1.24–1.80) of short sleep duration, 1.21 (1.11–1.44) of long sleep duration and 2.53 (1.85–3.46) for insomnia. The association of other sleep problems with multimorbidity was narratively summarized due to limited number of comparable studies.Conclusion: Abnormal sleep duration and insomnia are associated with higher odds of multimorbidity, while the evidence on association of snoring, poor sleep quality, obstructive sleep apnea and restless legs syndrome with multimorbidity remains inconclusive. Interventions targeting sleep problems should be delivered for better management of multimorbidity.
Molecular Phylogenies of Leeches and Haemoparasites Infecting Freshwater Turtles in Aquatic Ecosystems of Northern Africa Suggest Phylogenetic Congruence between Placobdella costata Sensu Lato and Haemogregarina stepanowi Sensu Lato
Authors: Verneau Olivier , Melliti Sirine , Kimdil Latifa , El Mouden El Hassan , Achouri Mohamed Sghaier , Rouag Rachid 
Published: June 2023

Haemogregarines are blood parasites with a life-cycle involving a vertebrate as the intermediate host and an invertebrate as the definitive host and vector. Extensive phylogenetic investigations based on 18S-rRNA gene sequences have shown that Haemogregarina stepanowi (Apicomplexa: Haemogregarinidae) is able to infest a large diversity of freshwater turtle species, including the European pond turtle Emys orbicularis, the Sicilian pond turtle Emys trinacris, the Caspian turtle Mauremys caspica, the Mediterranean pond turtle Mauremys leprosa, and the Western Caspian turtle Mauremys rivulata, among others. From the same molecular markers, H. stepanowi is further considered to be a complex of cryptic species predisposed to infect the same host species. While Placobdella costata is known to be the unique vector of H. stepanowi, it is only recently that independent lineages within P. costata have been illustrated—suggesting the presence of at least five unique leech species across Western Europe. The aims of our study were therefore to investigate from mitochondrial markers (COI) the genetic diversity within haemogregarines and leeches infecting freshwater turtles of the Maghreb, in order to identify processes of parasite speciation. We showed that H. stepanowi consists of at least five cryptic species in the Maghreb, while two Placobella species were identified in the same area. Although an Eastern–Western speciation pattern was apparent for both leeches and haemogregarines, we cannot make definitive conclusions regarding co-speciation patterns between parasites and vectors. However, we cannot reject the hypothesis of a very strict host–parasite specificity within leeches.
Quantum Probability from Temporal Structure
Authors: Ridley Michael 
Published: June 2023

The Born probability measure describes the statistics of measurements in which observers self-locate themselves in some region of reality. In ψ-ontic quantum theories, reality is directly represented by the wavefunction. We show that quantum probabilities may be identified using fractions of a universal multiple-time wavefunction containing both causal and retrocausal temporal parts. This wavefunction is defined in an appropriately generalized history space on the Keldysh time contour. Our deterministic formulation of quantum mechanics replaces the initial condition of standard Schrödinger dynamics, with a network of ‘fixed points’ defining quantum histories on the contour. The Born measure is derived by summing up the wavefunction along these histories. We then apply the same technique to the derivation of the statistics of measurements with pre- and postselection.
#ChronicPain: Automated Building of a Chronic Pain Cohort from Twitter Using Machine Learning
Authors: Sarker Abeed , Lakamana Sahithi , Guo Yuting , Ge Yao , Leslie Abimbola , Okunromade Omolola , Gonzalez-Polledo Elena , Perrone Jeanmarie , McKenzie-Brown Anne Marie 
Published: June 2023

BackgroundDue to the high burden of chronic pain, and the detrimental public health consequences of its treatment with opioids, there is a high-priority need to identify effective alternative therapies. Social media is a potentially valuable resource for knowledge about self-reported therapies by chronic pain sufferers.MethodsWe attempted to (a) verify the presence of large-scale chronic pain-related chatter on Twitter, (b) develop natural language processing and machine learning methods for automatically detecting self-disclosures, (c) collect longitudinal data posted by them, and (d) semiautomatically analyze the types of chronic pain-related information reported by them. We collected data using chronic pain-related hashtags and keywords and manually annotated 4,998 posts to indicate if they were self-reports of chronic pain experiences. We trained and evaluated several state-of-the-art supervised text classification models and deployed the best-performing classifier. We collected all publicly available posts from detected cohort members and conducted manual and natural language processing-driven descriptive analyses.ResultsInterannotator agreement for the binary annotation was 0.82 (Cohen’s kappa). The RoBERTa model performed best (F1score: 0.84; 95% confidence interval: 0.80 to 0.89), and we used this model to classify all collected unlabeled posts. We discovered 22,795 self-reported chronic pain sufferers and collected over 3 million of their past posts. Further analyses revealed information about, but not limited to, alternative treatments, patient sentiments about treatments, side effects, and self-management strategies.ConclusionOur social media based approach will result in an automatically growing large cohort over time, and the data can be leveraged to identify effective opioid-alternative therapies for diverse chronic pain types.
Cinta Kasih Refleksi Kritis Atas Intoleransi Kehidupan Beragama Di Indonesia Dari Konsep Cinta Kasih Søren A. Kierkegaard
Authors: Poli Rikhardus , Wijanarko Robertus 
Published: June 2023

This study focuses on exploring the concept of love according to Soren Kierkegaard's thoughts as a symbol of faith in the midst of the outbreak of religious discrimination in Indonesia. The purpose of this paper is to understand the concept of love according to Soren Kierkegaard and its relevance for religious discrimination that often occurs in Indonesia. Discrimination is common in religious life. The reason is because religion tends to be seen from the building and its rites. The religion that actually contains the values of goodness, truth and the highest value of love is narrowed in meaning. Values whose meaning is very positive and contained in the Scriptures of every religion have narrowed meanings. Religion as a place where the value of love grows is finally sacrificed due to the narrow understanding of its adherents. Soren Kierkegaard gives a very deep understanding of love. This philosopher of existentialism posits about the stages of human life, namely the aesthetic stage, the ethical stage and the religious stage. The concept of love also undergoes changes as human life progresses according to the three stages of human life. The author uses a phenomelogical approach and uses literature studies in completing this paper. According to the author, the concept of love in Kierkegaard's thinking provides the right relevance to the outbreak of religious discrimination that occurred in Indonesia.
Reksa Pastoral Care Elaborasi Pendekatan Holistik bagi Pendampingan Lanjut Usia
Authors: Yulius Martinus Irwan 
Published: June 2023

One of the church's attention and concern in pastoral work is pastoral care. Pastoral care becomes an integral part of the church's mission in proclaiming God's work of salvation. Pastoral care within the framework of caring for the souls of the faithful is carried out in different contexts based on the age, situation, and needs of the people. One of the works that the church has been engaged in is pastoral care for the elderly people. These elderly people have different and special characters, situations and needs. The purpose of this research is how to pay attention to all dimensions of life (biopsychosociospiritual) in assisting the elderly. The research method used in this research is literature study; This elaboration will be complemented by data and facts taken from existing studies on this area of study. The results of this study show several practical steps that can be taken
to provide integral assistance to elderly people.
EFECTIVIDAD DEL MOUSSE DE SANGRECITA Y NIVEL DE HEMOGLOBINA EN LOS NIÑOS DE 3 AÑOS EN LAS INSTITUCIONES EDUCATIVAS INICIALES, ICA - PERÚ
Authors: Echegaray Suarez Manuel Alejandro , Tovar Cárdenas Maryorin Camila , Flores Tintaya Luz María , Espino Canales Celia Pamela , Valentín Saccatoma Angélica María , Vílchez Carpio Yevet Alexandra , Liñán Hurtado Kelly , Mantari Camara Geraldine Teresa 
Published: June 2023

El estudio tuvo como Objetivo: Evaluar la efectividad del mousse de sangrecita en los niveles de hemoglobina en los niños de dos instituciones Educativas iniciales. Materiales y métodos: Estudio Experimental con diseño cuasi experimental de corte longitudinal, la población de estudio estuvo conformada por 80 niños los cuales todos participaron (consentimiento de los padres), 52 niños fueron de la IEI de Ica y 28 de la IEI de Comatrana, para la muestra se realizó un muestreo no probabilístico mediante el descarte de anemia utilizando el analizador de hemoglobina (hemoQ), microcubetas, lancetas y demás implementos, de ellos 9 niños tuvieron una hemoglobina <=11gr/dl quienes ingresaron al programa de mousse de sangrecita. Se elaboró una ficha de control. Resultados: Después de 7 semanas de consumir el mousse de sangrecita los 9 niños que ingresaron al programa de las dos IEI, se evidencio un incremento en sus niveles de hemoglobina superior al primer control. Conclusiones: El consumo de mousse de sangrecita es efectiva en el tratamiento de la anemia en niños de la IEI incrementando el nivel de hemoglobina.
Peramalan Jumlah Kedatangan Wisatawan Mancanegara di Sulawesi Selatan Menggunakan Model ARFIMA
Authors: Sukarna Sukarna , Abdy Muhammad , Aswi Aswi , Kaito Nurkaila 
Published: June 2023

Pariwisata dianggap sebagai suatu aset yang strategis untuk mendorong pembangunan pada wilayah-wilayah tertentu yang mempunyai potensi objek wisata. Faktor-faktor yang mempengaruhi wisatawan mancanegara berkunjung ke suatu wilayah negara, diantaranya nilai tukar mata uang, inflasi disuatu wilayah kunjungan wisatawan, dan letak geografis suatu wilayah negara. Peningkatan yang tidak terduga pada jumlah kunjungan wisatawan ini dapat berdampak kesulitan bagi para pelaku wisatawan dalam hal memberikan pelayanan terbaik dan sebaliknya jika terjadi penurunan jumlah kunjungan wisatawan hal yang dikhawatirkan akan terjadi pengangguran.Oleh karena itu, diperlukan suatu peramalan yang dapat memberikan informasi atau gambaran pada proses jumlah kunjungan wisatawan mancanegara. Dalam analisis runtun waktu terdapat data yang memiliki ciri proses jangka pendek dan data yang memiliki ciri proses jangka panjang. Model yang dapat menangani kedua jenis data ini adalah model autoregressive fractionally integrated moving average (ARFIMA). Model ARFIMA merupakan pengembangan dari model ARIMA, dengan differencing bernilai pecahan. Penelitian ini bertujuan untuk menentukan model ARFIMA pada peramalan jumlah kunjungan wisatawan mancanegara Sulawesi Selatan di masa yang akan datang. Pada penelitian ini, nilai AIC antara ARFIMA([1,8],d,0) dengan d ̂_gph=0,02 dan ARFIMA(0,d,1) dengan d ̂_(R/S)=0,12 relatif sama, hasil komparasi dengan model ARIMA memberikan hasil bahwa tidak diperoleh nilai ARIMA yang sesuai sehingga penulis menggunakan model ARFIMA untuk peramalan dan hasil peramalan jumlah kedatangan wisatawan mancanegara Sulawesi Selatan dapat dilihat dengan perbandingan data out sample.Keywords: Parawisata, peramalan, ARFIMA.