bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative study of growth and HSP70 gene expression in Japanese quails fed different levels of Black Soldier Fly, Hermetia illucens
Authors: El-Sayed MohammedAhmed , Hatab Mahmoud H , Ibrahim Nashaat S , Assi HebaAbdelwahab Mahmoud , Saleh Hisham M , Sayed Waheed AA , Rumpold Birgit A 
Published: December 2022

Abstract

Background:Edible insects are considered a promising nutritious, sustainable alternative protein source for feed. The effect of black soldier fly (Hermetia illucens), meal on growth performance, heat stress-responses (HS) and heat shock protein (HSP70) gene expression in gendered Japanese quail were assessed. The quails were fed on three different diets containing 100% soybean meal (diet A), 50% soybean and 50% Hermetia illucensmeal (diet B) and 100% Hermetia illucensmeal (diet C).
Results:the results revealed that overall live body weight(LBW), the relative weight of carcass, small intestine, heart, liver, gender organs, spleen and bursa of Fabriciusof quails were significantly elevated for diet B and C as compared to diet. A. The interaction of dietary treatment and HS had a significant effect on the diet A group's LBW, the relative weight of carcass, and measured organs, whereas the diet B and diet C groups had no or least effect on their traits. Investigating HSP70 gene expressionwith HS exposure in control diet A was 13.215. While, the diet B was expressed of 8.487with the HSP70 gene. Moreover, the gene expression of the birds fed on diet C was3.203.
Conclusion:Our findings point to a beneficial role for Hermetia illucensmeal as a quail feed in improving growth performance and combating the negative effects of HS exposure on bird growth.
Does Renewable Energy affect Environmental Sustainability? Nexus among Renewable Energy Consumption, Trade Openness, CO2 Emissions, Income Inequality and Economic Growth
Authors: Ramos-Meza Carlos Samuel , Arocutipa Javier Pedro Flores , Huallpa Jorge Jinchuña , Palomo Erika Eleana Corzo , Huarcaya Valery Kimiyo Gamero , Acuña Yeni Gutiérrez , Martinez Juan Carlos Valencia 
Published: December 2022

AbstractThis research explores the relationship among renewable energy consumption (REC), trade openness, carbon emanations, and income inequality on economic growth. This study takes fifteen (15) OECD nations data sets starting from 1997 to 2020 by employing the AMG assessor, which takes into account slope heterogeneity (SH) and CSD. The empirical outcomes confirm a significant favorable long-run relationship between these nexuses, except for carbon emanations, which are adversely related to REC. Notwithstanding, it has been discovered that there is bidirectional causality between income inequality and REC.JEL Classification:D47
The Impact of Waiting Time for Total Hip Arthroplasty on Progression of Hip Osteoarthritis
Authors: Brunnader Lars , Draschl Alexander , Smolle Maria , Leitner Lukas , Leithner Andreas , Maurer-Ertl Werner 
Published: December 2022

Abstract

Aims: The aim of this study was to discover possible correlations between longer waiting times and radiologically visible deterioration of hip osteoarthritis in a retrospective, single-centre study.
Methods: Radiographs of the affected hip taken at time of registration in the institution’s waiting list as well as x-rays of the same hip at time of hospital admission for THA were ascertained together with demographic and clinical variables. Correlations between waiting time and changes in radiological criteria, as well as deterioration of hip osteoarthritis and clinical variables, were analysed with uni- and multivariate logistic regression analysis.
Results: Median waiting time was 19.5 weeks (IQR: 8.3 – 29.7 weeks). Patients experiencing deterioration of hip osteoarthritis from initial to preoperative x-ray, as reflected by increasing KL score (n=47; median waiting time 26.7 weeks [IQR: 15.0 – 39.4]) had a significantly longer waiting time for THA than patients without worsening of hip osteoarthritis (n=245; median waiting time 18.9 weeks [IQR: 7.7 – 29.0]; p<0.001). There was no significant difference in waiting time depending on gender (p=0.545), cup destruction (p=0.682), or patient age (F(1.290) = 0.11; p=0.835). Notably, no significant correlation between likelihood of hip osteoarthritis progression and patient age (p=0.813), CAM-type impingement (p=0.319), coxa profunda (p=0.116) or gender (p=0.064) was found. In the multivariate logistic regression model, time delay until THA remained significantly associated with worsening of hip osteoarthritis, irrespective of gender, CAM type impingement and coxa profunda at baseline.
Conclusion: Our findings support the assumption that longer waiting times may lead to worsening of radiological signs of hip osteoarthritis.
Educational Intervention Based on Health Action Model to Promote Safe Behavior of Hospital Workers
Authors: Mohammadi Maryam , Vahedian-sharoodi Mohammad , Joghatei Zahra , Esmaily Habibullah , Tehrani Hadi 
Published: December 2022

Abstract
Background:

Hospitals are the most dangerous health service centers in the health system, and their service workers are exposed to all kinds of serious risks, which in some cases are life-threatening. So The purpose of this study was to investigate the effect of educational intervention based on the Health action model to promote the safe behavior of hospital workers.

Methods:

Several 45 workers in each of the control and intervention groups participated in a quasi-experimental study. Demographic information and data related to health action model constructs were collected through a questionnaire and a checklist, immediately and three months after the intervention. Cronbach's alpha coefficients were used to confirm the properties of the tools. Educational intervention accompanied was applied in the form of four training classes. The data were analyzed using SPSS 20 software.

Results:

Before the intervention, there was no significant difference between the two groups in terms of demographics and the study’s main variables. Three months after the intervention training, however, results showed significant changes in mean scores of safe behavior (12.53 ± 1.68), Attitude (16.06 ± 2.6), norms (29.24 ± 4.25), belief (52.71 ± 4.42), intention (33.24 ± 1.44), knowledge (41.97 ± 1.68) in the experimental group (P < 0.001).

Conclusions:

The research results show that Health action model educational intervention can change workers’ awareness, attitudes, norms, beliefs, and intentions toward unsafe behavior and improve their safety performance.
Trial registration: IRCTID: IRCT20160619028529N7
3rd Degree Polynomial Model: Is It Best Non-Linear Model for the Estimation of Growth Curve in Anatolian Black Cattle?
Authors: SAKAR Çağrı Melikşah , Koncagül Seyrani , ÜNAL İlker 
Published: December 2022

Abstract

In this study, it was aimed to estimate the growth curve of live weights from birth to 24 months of age in Anatolian Black Cattle raised for conservation purposes. For this purpose, a total of 493 weight records of 113 animals at birth, 3, 6, 12, 18 and 24 months were examined in the study. Six different non-linear models were used to describe the growth curve of animals, these are 2nd degree polynomial, 3rd degreee polynomial, Logistic, Brody, Von Bertalanffy and Gompertz models. In the study, R2 values of these models determined 0.997, 0.999, 0.953, 0.979, 0.924 and 0.862; corel (correlation between the observed and estimated) were 0.994, 0.998, 0.989, 0.993, 0.961 and 0.703; Residual Standart Deviation were 3.216, 1.388, 11.533, 3.561, 14.736 and 27.141 respectively. According to these values, it was determined that the 3rd degree polynomial model was best described the growth curve of Anatolian Black. As a result of the analyses, it was determined that the values predicted by this model deviated by 1–3 kg from the observed values in all periods and in all environmental factors examined (sex, dam age, parity, birth year and birth season). It was determined that these differences increased up to 4–5 kg only in the 18-month period. The results also showed that Anatolian Black continued to grow after 24 months of age. As a result, activities such as sexual maturity age, breeding age and slaughter age can be easily predicted by determining the model that best describes growth and development in herds.
Joint extraction of Chinese medical entities and relations based on RoBERTa and single-module global pointer
Authors: Li Dongmei , Yang Yu , Cui Jinman , Meng Xianghao , Qu Jintao , Zhang Xiaoping 
Published: December 2022

Abstract

Background: Most Chinese joint entity and relation extraction tasks in medicine involve numerous nested entities, overlapping relations, and other challenging extraction issues. In response to these problems, some traditional methods decompose the joint extraction task into multiple steps or multiple modules, resulting in local dependency in the meantime.
Methods: To alleviate this issue, we propose a joint extraction model of Chinese medical entities and relations based on RoBERTa and single-module global pointer, namely RSGP, which formulates joint extraction as a global pointer linking problem. Considering the uniqueness of Chinese language structure, we introduce the RoBERTa-wwm pre-training language model at the encoding layer to obtain a better embedding representation. Then, we represent the input sentence as a three-dimensional matrix and score each position in the matrix to prepare for the subsequent process of decoding the triples. In the end, we design a novel single-module global pointer decoding approach to alleviate the generation of redundant information. Specifically, we analyze the decoding process of single character entities individually, improving the time and space performance of RSGP to some extent.
Results: In order to verify the effectiveness of our model in extracting Chinese medical entities and relations, we carry out the experiments on the public dataset, CMeIE. Experimental results show that RSGP performs significantly better on the joint extraction of Chinese medical entities and relations, and achieves state-of-the-art results compared with baseline models.
Conclusion: The proposed RSGP can effectively extract entities and relations from Chinese medical texts and help to realize the structure of Chinese medical texts, so as to provide high-quality data support for the construction of Chinese medical knowledge graphs.
Sleep disturbances are associated with irritability in ASD children with sensory sensitivities
Authors: Haimovich Alona Molcho , Tikotzky Liat , Meiri Gal , Ilan Michal , Michaelovski Analya , Schtaierman Hen , Golan Hava M. , Sadaka Yair , Menashe Idan , Dinstein Ilan 
Published: December 2022

Abstract
Background: Parent reports suggest that 44-84% of children with ASD exhibit sleep disturbances that are of clinical concern. Previous studies have reported that, in children with ASD, the severity of sleep disturbances is associated with the severity of either sensory problems or aberrant behaviors, but none have performed combined analyses with measures of both sensory and aberrant behaviors symptom domains from the same children.
Methods: we examined parent reports of 237 children with ASD, 1.4-8.7 years old, using the child sleep habits questionnaire (CSHQ), sensory profile (SP), and aberrant behaviors checklist (ABC).
Results: The analyses revealed that sleep disturbances were most strongly associated with SP sensory sensitivity and ABC irritability scores. Together these scores explained 35% of the variance in total CSHQ scores. Moreover, sensory sensitivity scores moderated the association between irritability and sleep disturbances, indicating that sleep disturbances were significantly associated with irritability only in children with moderate to severe sensory sensitivities.
Conclusion: We suggest that the three symptom domains may interact and exacerbate each other such that successful intervention in one symptom domain may have positive impact on the others. Further intervention studies testing this hypothesis are highly warranted.
Trial registration: N/A
Do Multilateral Environmental Agreements Explain Vulnerability to Climate Change in Developing Countries?
Authors: TSOMB Etienne Inedit Blaise TSOMB , Atangana Henri Ondoa 
Published: December 2022

Abstract
Developing countries (DCs), despite their low contribution to global greenhouse gas emissions, are now among the most active countries in multilateral environmental agreements (MEAs). This growing interest of developing countries in multilateral environmental agreements comes at a time when the scale of climate change and its consequences for developing countries are tending to increase. This article, therefore, aims to examine the role of MEAs in the vulnerability of developing countries to climate change. The study is conducted using panel data collected from 72 developing countries between 1995 and 2017. The results obtained by the two stages least squares method applied on a fixed effects panel show that MEAs reduce the vulnerability to climate change of DCs. However, the results also show that this effect varies according to the sector or the component of vulnerability to climate change considered. Thus, it appears that MEAs reduce vulnerability to climate change in the ecosystem, infrastructure, housing, and water sectors, whereas they increase vulnerability to climate change in the food and health sectors. Furthermore, the effect of MEAs on vulnerability to climate change increases with the degree of preparedness of developing countries to effectively use climate change adaptation investments. Finally, the results show that the level of development and the geographical location of developing countries have an impact on their vulnerability to climate change.
JEL Classification: Q40, Q54, Q58
Genome-wide transcriptional profiling provides clues to molecular mechanisms underlying cold tolerance in chickpea
Authors: Akbari Alireza , Ismaili Ahmad , Amirbakhtiar Nazanin , Pouresmael Masoumeh , Shobbar Zahra-Sadat 
Published: December 2022

Abstract
Chickpea is an important food legume cultivated in several countries. A sudden drop in autumn temperature, freezing winter temperature, and late spring cold events result in significant losses in chickpea production. The current study used RNA sequencing of two cold tolerant (Saral) and sensitive (ILC533) Kabuli chickpea genotypes to identify cold tolerance-associated genes/pathways. A total of 200.85 million raw reads were acquired from the leaf samples by Illumina sequencing, and around 86% of the clean reads (199 million) were mapped to the chickpea reference genome. The results indicated that 3710 (1980 up- and 1730 down-regulated) and 3473 (1972 up- and 1501 down-regulated) genes were expressed differentially under cold stress in the tolerant and sensitive genotypes, respectively. According to the GO enrichment analysis of uniquely down-regulated genes under cold stress in ILC533, photosynthetic membrane, photosystem II, chloroplast part, and photosystem processes were enriched, revealing that the photosynthesis is severely sensitive to cold stress in this sensitive genotype. Many remarkable transcription factors (CaDREB1E, CaMYB4, CaNAC47, CaTCP4, and CaWRKY33), signaling/regulatory genes (CaCDPK4, CaPP2C6, CaMKK2, and CaHSFA3), and protective genes (CaCOR47, CaLEA3, and CaGST) were identified among the cold-responsive genes of the tolerant genotype. These findings would help improve cold tolerance across chickpea genotypes by molecular breeding or genetic engineering.
Translation and transcultural adaptation of the Migrasalud questionnaire for the assessment of mental health and well-being in the migratory process
Authors: Mellor-Marsá Blanca , Franch-Roca Marta , Butt Fajar Matloob Ahmed , Elmokhtari Rachid El Hafi , Villalobos Felipe , He Yuelu , Rahhab Wafae Moussaoui , Qureshi Shazra Javed , Begum Misbah Yousaf , Schiller Iris Andrea González , González Sergio Salinas , Bayes-Marin Ivet , Gabarrell-Pascuet Aina , Alós-Belenguer Mª Carmen , Lloret-Pineda Amanda , Ayad-Ahmed Wala , Sainz-Elías Helena , Roura-Adserias María , Lopez Gema Fariñas , Salomon-Mallat Elisabet , López Yolanda Osorio , Cabeza Mercedes Espinal , Pareja Lola Aparicio , Bobo Óscar D Alvarez , Haro Josep Maria , Cristóbal-Narváez Paula 
Published: December 2022

Abstract
Background: The aim of the present study was to follow different language adaptation steps towards conceptual equivalence to guarantee the cross-cultural applicability of an instrument that explored the relationship between migration, and mental health barriers and protective factors. The procedures followed during the process may provide practical guidance for intercultural research designs.
Methods: A translation protocol based on a cross-cultural study aiming (+18) migrants who arrived in Barcelona in the last 5 years –most frequently Pakistani, Arabic, Chinese, English but also Latino or Spanish-speaking communities- was developed consisting on four stages -1) translation; 2) back-translation; 3) synthesis and 4) pre-testing- and applied to individuals in a sample representative of the 5 target languages-. Team-based translation experts, multicultural translators and a systematically constructed method for translation and back-translation from source and target languages where some of the strategies for transparency and reproducibility of scientific methods.
Discussion: The present work implied the translation and back-translation of the instrument and was comprehensively conducted to achieve concept equivalence between the original questionnaire version with the translated version in detecting mental health deterioration or empowerment in the context of international migration.
Trial registration: not applicable
Resolution of an insidious and migratory Mycobacterium tuberculosis- associated secondary organizing pneumonia: A case report and literature review
Authors: Huang Li-Li , Wang Chun , Liu Ying , Gu Xiao-Yan , Wang Wei-Xiao , Chen Wei , Hu Chun-Mei 
Published: December 2022

Abstract
Background: Organizing pneumonia (OP) is a rare interstitial lung disease. Secondary organizing pneumonia (SOP) caused by Mycobacterium tuberculosis (MTB) is extremely rare. Migratory MTB-associated SOP is more deceptive and dangerous. When insidious tuberculosis (TB) is not recognized, SOP would be misdiagnosed as cryptogenic organizing pneumonia (COP). Use of steroid hormone alone leads to the progression of TB foci or even death. Clues of distinguishing atypical TB at the background of OP is urgently needed.
Case presentation: A 56-year-old female patient was hospitalized into the local hospital because of cough and expectoration for more than half a month. Her medical history and family history showed no relation to TB or other lung diseases. Community-acquired pneumonia was diagnosed and anti-infection therapy was initialized but invalid. The patient suffered from continuous weigh loss. More puzzling, the lesions were migratory based on CT images. The patient was then transferred to our hospital. The immunological indexes of infection in blood and pathogenic tests in sputum and the bronchoalveolar lavage fluid were negative. The percutaneous lung puncture biopsy and pathological observation confirmed OP, but without granulomatous lesions. Additionally, pathogen detection of the punctured lung tissues by mNGS were all negative. COP was highly suspected. Fortunately, the targeted next-generation sequencing (tNGS) detected MTB in the punctured lung tissues and MTB-associated SOP was definitely diagnosed. The combined therapy of anti-TB and prednisone was administrated. After treatment for 10 days, the partial lesions were significantly resorbed and the patient was discharged. In the follow-up of half a year, the patient was healthy.
Conclusions: It is difficult to distinguish SOP from COP in clinical practice. Diagnosis of COP must be very cautious. Transient small nodules and cavities in the early lung image are a clue to consider TB, even though all pathogen tests are negative. tNGS is also a powerful tool to detect pathogen, ensuring prompt diagnosis of TB-related SOP. For clinicians in TB high burden countries, we encourage them to keep TB in mind before making a final diagnosis of COP.
Hybridization of papain molecules and DNA- wrapped single-walled carbon nanotubes evaluated by atomic force microscopy in fluids
Authors: Kitamura Masaki , Umemura Kazuo 
Published: December 2022

Abstract
Although various conjugates of single-walled carbon nanotubes (SWNTs) and biomolecules, such as nanobiosensors and nanobiodevices, have been reported, the conjugation of papain and SWNTs have not been reported because of the formation of unexpected aggregates. In this study, atomic force microscopy (AFM) in liquid was used to investigate the interactions between papain and DNA-wrapped SWNTs (DNA–SWNTs) at two different pH values (pH 3.0 and 10.5). The direct AFM observation of the mixture of papain and DNA–SWNTs confirmed the aggregation of papain molecules with DNA–SWNTs in the buffer solutions. The numerous and non-uniform adsorption of papain molecules onto DNA–SWNTs was more pronounced at pH 3.0 than that at pH 10.5. Furthermore, thick conjugates appeared when papain and DNA–SWNTs were simultaneously mixed. The near-infrared photoluminescence spectra of the SWNTs drastically changed when the papain molecules were injected into the DNA–SWNT suspension at pH 3.0. Thus, the regulation of electrostatic interactions is a key aspect in preparing optimal conjugates of papain and DNA–SWNTs. Furthermore, although previous papers reported AFM images of dried samples, this study demonstrates the potential of AFM in liquid in evaluating individual bioconjugates of SWNTs.
Violence Against Doctors Working in Paediatric Hospitals in Khartoum State, Sudan: Frequency and Risk Factors
Authors: Musaad Walaa , Arabi A. M 
Published: December 2022

Abstract

Background:Healthcare workplace violence (WPV) is under-reported, universal and it is not given enough attention in medical education and continuing professional development (CPD). Incidents originated from multiple factors related to the patient, doctor, and organization. Effective training and awareness are key corners to tackling the problem.Objectives:To study the frequency and risk factors of violence among doctors working in paediatric hospitals in Khartoum state.Methodology:Descriptive cross-sectional study in 4 paediatric hospitals in Khartoum state in 2021, involving 189 doctors. Data was collected using a semi-structured, self-administrated questionnaire.Results:It was found that 152 (80.4%) were females and 37 (19.6%) were males. Violence has been encountered by 65.6% during their entire career in paediatric medical service. 74.6% have been exposed to one or more types of violence during the past year. Out of them, 86.2% and 11.32% encountered emotional violence and physical violence respectively. 1 in 50 victims experienced sexual harassment. No association was elicited between exposure to any type of violence and gender, age, length of service, or marital status. There was a strong association between professional level and experiencing violence (p-value 0.000) and particularly emotional violence (p-value 0.000). The lesser professional experiences the more it is likely to face emotional violence. About half of emotional, physical, and sexual violence victims did not react after the event. Those who experienced physical violence have a higher frequency rate of reporting violence than participants who experienced other violent types and this reporting was mostly to the superior i.e., informally. Only 5% of the participants got training in violence prevention and management.Conclusion:Violence is common among doctors in paediatric hospitals. Attention should be paid to improving doctor-patient settings and investing in violence prevention and management education.