bluuebunny/crossref_metadata_2025_split huggingface dataset:
Financial distress and service decisions: Empirical evidence from the US domestic airlines
Authors: Ma Qian , Wang Guojun 
Published: March 2023

AbstractUnderstanding the firm's service decisions under financial distress is of central importance to service quality regulators and operation management scholars. This study aims to add new evidence to the relationship between financial distress and airline services and reconcile the discrepancies between theory, practical implications, and empirical results. We examine if and how airlines in financial distress may change their service provisions to turn around, with a particular focus on the moderating role of operating unit costs and market share. In the study, four measures of service failure (the inverse of service quality) are constructed and evaluated: airline arrival delay minutes attributable to the carrier, cancelations attributable to the carrier, mishandled baggage, and involuntary denied boardings. In the US domestic airline business context, we estimate the mixed‐effects model using panel data from the Department of Transportation and Wharton Research Data Services. We find robust evidence that financial distress plays a vital role in airline service provisions, and the distress–service relationship is contingent upon the operating unit costs of airlines. The findings provide evidence to help explain the different and sometimes contradictory empirical findings. We depend on the aggressive strategy framework to understand the service effect of airline financial distress.
Healthy bladder storage and emptying functions in community‐dwelling women measured by a 2‐day bladder health diary
Authors: Lukacz Emily S. , Falke Chloe , Geynisman‐Tan Julia , Wyman Jean F. , Mueller Elizabeth R. , Markland Alayne D. , Rickey Leslie , Lowder Jerry L. , Rudser Kyle , Kane Low Lisa , Newman Diane K. ,   the Prevention of Lower Urinary Tract Symptoms (PLUS) Research Consortium
Published: March 2023

AbstractIntroductionThe prevalence of healthy bladder storage and emptying function in community‐dwelling women is not well established.MethodsA planned secondary analysis of a US cross‐sectional study designed to validate a bladder health instrument was conducted in women aged ≥18 years. A subset was invited to complete the novel 2‐day bladder health diary capturing bladder storage and emptying experiences. Overall healthy bladder function was defined as ≤8 waking/daytime voids and ≤1 void during sleeping/nighttime; along with the absence of leakage, urgency, emptying difficulties (initiation, flow, efficacy, relief of urge sensation) and pain. Descriptive statistics of healthy bladder functions and regression models of factors associated with healthy function are reported.ResultsOf the 383 invited, 237 (62%) eligible women returned complete dairies. Of these, 12% (29/237) met criteria for overall healthy bladder function. Most (96%) denied pain, 74% had healthy daytime and 83% had healthy nighttime voiding frequency, 64% were continent, 36% reported healthy emptying and 30% denied any urgency episodes. Middle income (odds ratio [OR]:95% confidence interval [CI] = 11.4:1.9–67.4 for $75k–$99 999 vs. $25 000–$49 999), Graduate education (4.8:1.4–17) and previously seeking treatment for bladder problems (OR:95%CI = 0.1; 0–0.9) were associated with overall healthy function.ConclusionThe prevalence of overall healthy bladder function was very low based on our strict definition of health as measured on a 2‐day diary. However, most women had healthy voiding frequency and denied pain or urinary leakage. Postvoid dribbling and urgency most commonly contributed to an overall unhealthy bladder. Further investigation is needed to determine whether these diary derived measures are meaningful for patient‐oriented bladder health research.
Simultaneous estimation of the cellular water exchange rate, intracellular volume fraction, and longitudinal relaxation rate in cancer cells
Authors: Kiser Karl , Zhang Jin , Qayyum Sawwal , Bracken W. Clay , Kim Sungheon Gene 
Published: March 2023

AbstractThe purpose of the current study was to investigate the feasibility of simultaneously estimating the cellular water efflux rate (
), intracellular longitudinal relaxation rate (
), and intracellular volume fraction (
) of a cell suspension using multiple samples with different gadolinium concentrations. Numerical simulation studies were conducted to assess the uncertainty in the estimation of
,
, and
from saturation recovery data using single (SC) or multiple concentrations (MC) of gadolinium‐based contrast agent (GBCA). In vitro experiments with 4 T1 murine breast cancer and SCCVII squamous cell cancer models were conducted at 11 T to compare parameter estimation using the SC protocol with that using the MC protocol. The cell lines were challenged with a Na+/K+‐ATPase inhibitor, digoxin, to assess the treatment response in terms of
,
, and
. Data analysis was conducted using the two‐compartment exchange model for parameter estimation. The simulation study data demonstrate that the MC method, compared with the SC method, reduces the uncertainty of the estimated
by decreasing the interquartile ranges from 27.3% ± 3.7% to 18.8% ± 5.1% and the median differences from ground truth from 15.0% ± 6.3% to 7.2% ± 4.2%, while estimating
and
simultaneously. In the cell studies, the MC method demonstrated reduced uncertainty in overall parameter estimation compared with the SC approach. MC method‐measured parameter changes in cells treated with digoxin increased
by 11.7% (p = 0.218) and
by 5.9% (p = 0.234) for 4 T1 cells, respectively, and decreased
by 28.8% (p = 0.226) and
by 1.6% (p = 0.751) for SCCVII cells, respectively.
did not change noticeably by the treatment. The results of this study substantiate the feasibility of using saturation recovery data of multiple samples with different GBCA concentrations for simultaneous measurement of the cellular water efflux rate, intracellular volume fraction, and intracellular longitudinal relaxation rate in cancer cells.
Importance of self‐weighing to avoid post‐cessation weight gain: A secondary analysis of the fit and quit randomized trial
Authors: Oswald Mackenzi , Ross Kathryn M. , Sun Ning , Yin Wupeng , Garcia Stephanie J. , Bursac Zoran , Krukowski Rebecca A. 
Published: March 2023

AbstractBackgroundSmoking cessation is associated with weight gain, and the risk of weight gain is a common deterrent to quitting smoking. Thus, the identification of strategies for reducing post‐smoking cessation weight gain is critical.ObjectiveConduct secondary analysis of data from the Fit & Quit trial to determine if greater frequency of self‐weighing is associated with less weight gain in the context of smoking cessation.MethodsParticipants (N = 305) were randomized to one of three 2‐month weight interventions (i.e., Stability, Loss, Bibliotherapy), followed by a smoking cessation intervention. Stability and Loss conditions received different types of self‐weighing feedback. All participants received e‐scales at baseline, to capture daily self‐weighing data over 12 months. General linear models were applied to test the main objective.ResultsFrequency of self‐weighing was (mean ± SD) 2.67 ± 1.84 days/week. The Stability condition had significantly higher self‐weighing frequency (3.18 ± 1.72 days/week) compared to the Loss (2.51 ± 1.99 days/week) and the Bibliotherapy conditions (2.22 ± 1.63 days/week). Adjusting for baseline weight and treatment condition, self‐weighing 3–4 days/week was associated with weight stability (−0.77 kg, 95% CI: −2.2946, 0.7474, p = 0.3175), and self‐weighing 5 or more days/week was associated with 2.26 kg weight loss (95% CI: −3.9249, −0.5953, p = 0.0080).ConclusionsSelf‐weighing may serve as a useful tool for weight gain prevention after smoking cessation. Feedback received about self‐weighing behaviors and weight trajectory (similar to the feedback Stability participants received) might enhance adherence.
Validation of diagnosis codes in healthcare databases in Taiwan, a literature review
Authors: Huang Yue‐Ton , Wei Tiffaney , Huang Ya‐Ling , Wu Yu‐Pu , Chan K. Arnold 
Published: March 2023

AbstractPurposeTo compile validation findings of diagnosis codes and related algorithms for health outcomes of interest from National Health Insurance (NHI) or electronic medical records in Taiwan.MethodsWe carried out a literature review of English articles in PubMed® and Embase from 2000 through July 2022 with appropriate search terms. Potentially relevant articles were identified through review of article titles and abstracts, full text search of methodology terms “validation”, “positive predictive value”, and “algorithm” in Subjects & Methods (or Methods) and Results sections of articles, followed by full text review of potentially eligible articles.ResultsWe identified 50 published reports with validation findings of diagnosis codes and related algorithms for a wide range of health outcomes of interest in Taiwan, including cardiovascular diseases, stroke, renal impairment, malignancy, diabetes, mental health diseases, respiratory diseases, viral (B and C) hepatitis, and tuberculosis. Most of the reported PPVs were in the 80% ~ 99% range. Assessment of algorithms based on ICD‐10 systems were reported in 8 articles, all published in 2020 or later.ConclusionsInvestigators have published validation reports that may serve as empirical evidence to evaluate the utility of secondary health data environment in Taiwan for research and regulatory purpose.
Building a feral future: Open questions in crop ferality
Authors: Mabry Makenzie E. , Bagavathiannan Muthukumar V. , Bullock James M. , Wang Hongru , Caicedo Ana L. , Dabney Clemon J. , Drummond Emily B. M. , Frawley Emma , Gressel Jonathan , Husband Brian C. , Lawton‐Rauh Amy , Maggioni Lorenzo , Olsen Kenneth M. , Pandolfo Claudio , Pires J. Chris , Pisias Michael T. , Razifard Hamid , Soltis Douglas E. , Soltis Pamela S. , Tillería Sofía , Ureta Soledad , Warschefsky Emily , McAlvay Alex C. 
Published: March 2023

Societal Impact StatementGiven the rapidly increasing drought and temperature stresses associated with climate change, innovative approaches for food security are imperative. One understudied opportunity is using feral crops—plants that have escaped and persisted without cultivation—as a source of genetic diversity, which could build resilience in domesticated conspecifics. In some cases, however, feral plants vigorously compete with crops as weeds, challenging food security. By bridging historically siloed ecological, agronomic, and evolutionary lines of inquiry into feral crops, there is the opportunity to improve food security and understand this relatively understudied anthropogenic phenomenon.SummaryThe phenomenon of feral crops, that is, free‐living populations that have established outside cultivation, is understudied. Some researchers focus on the negative consequences of domestication, whereas others assert that feral populations may serve as useful pools of genetic diversity for future crop improvement. Although research on feral crops and the process of feralization has advanced rapidly in the last two decades, generalizable insights have been limited by a lack of comparative research across crop species and other factors. To improve international coordination of research on this topic, we summarize the current state of feralization research and chart a course for future study by consolidating outstanding questions in the field. These questions, which emerged from the colloquium “Darwins' reversals: What we now know about Feralization and Crop Wild Relatives” at the BOTANY 2021 conference, fall into seven categories that span both basic and applied research: (1) definitions and drivers of ferality, (2) genetic architecture and pathway, (3) evolutionary history and biogeography, (4) agronomy and breeding, (5) fundamental and applied ecology, (6) collecting and conservation, and (7) taxonomy and best practices. These questions serve as a basis for ferality researchers to coordinate research in these areas, potentially resulting in major contributions to food security in the face of climate change.
In silico design of two‐photon fluorescent probes for detecting nitric oxide
Authors: Liu Xiaoting , Zhang Ji‐Long 
Published: March 2023

AbstractWith the extensive use of two‐photon fluorescence microscopy in the biology field, the need for developing fluorescent probes with preferred two‐photon absorption (TPA) properties has attracted great interest. Nitric oxide (NO) is a ubiquitous signaling molecule in a variety of physiological and pathological process in living organisms. A two‐photon (TP) probe, that is, 2‐acetyl‐6‐dialkylaminonaphthalene as the reporter and ano‐diaminobenzene as the reaction site for NO, linked by prolinamide (ANO1) has been synthesized. Based on the experimental study, five other TP probes have been theoretically designed by substituting the naphthalene fluorophore with luciferin, pyrene (substitution at 1,6‐position and 2,7‐position), fluorene, and boron‐dipyrromethene units. DFT/TDDFT studies have been conducted one‐photon absorption and emission properties as well as TPA. Our results indicated that both absorption and emission spectra of designed probes show red shifts compared withANO1. Moreover, the fluorescence intensities are enhanced after reaction with NO. Furthermore, molecular orbitals are analyzed to interpret the photoinduced electron transfer mechanism. Notably, introducing the fluorene moiety can induce the enhancement ofμ0nand Δμ0nand thus modulate TPA. Accordingly,ANO4is thought to be a promising candidate for novel TPA NO probe.
Research Progress of Cathode Materials for Rechargeable Aluminum Batteries in AlCl3/[EMIm]Cl and Other Electrolyte Systems
Authors: Zhang Boya , Zhang Wenyang , Jin Huixin , Wan Jiaqi 
Published: March 2023

AbstractThe development of safe, cheap, and environmentally friendly advanced rechargeable batteries with high energy density are one of the most pressing tasks for today‘s energy crisis. With the advantages of low cost, abundant reserves, and high‐level safety, rechargeable aluminum ion batteries are considered ideal candidates for next‐generation energy storage batteries in the context of large‐scale energy applications. Relevant knowledge of energy storage materials and electrolytes, which possess close connection in between, is undeniably crucial for such research, while ironically, most attention is attracted to merely one element alone, especially the energy storage materials involving micro/nanomaterials. In this review, we focus on cathode materials matching with various electrolyte systems for rechargeable aluminum batteries and manage to provide new ideas for the preparation methods of high‐efficiency electrochemical energy storage materials, with future outlooks in this field.
Synthesis of 2‐Chloro‐6‐(trifluoromethyl)pyridine‐3,5‐dicarbonitrile: A Versatile Building Block for the Synthesis of Substituted Trifluoro Methyl Pyridine Derivatives
Authors: Channapur Manjunath , Hall Roger G. , Kessabi Jilali , Montgomery Mark G. , Shyadligeri Ashok 
Published: March 2023

AbstractA simple and highly efficient (concise 3‐step) synthesis of 2‐chloro–6‐(trifluoromethyl)pyridine‐3,5‐dicarbonitrile has been developed from readily available starting materials. Furthermore, the selective reactivity of this tetra‐ substituted pyridine with different carbon, sulfur, nitrogen and oxygen nucleophiles offers great scope for the synthesis of novel highly substituted pyridine derivatives in decent to good yields.
Polysaccharide‐Based Stimulus‐Responsive Nanomedicines for Combination Cancer Immunotherapy
Authors: Li Qiuxia , Liu Xing , Yan Chunmei , Zhao Bolin , Zhao Yuxin , Yang Lu , Shi Mingyi , Yu Hua , Li Xiaofang , Luo Kaipei 
Published: March 2023

AbstractCancer immunotherapy is a promising antitumor approach, whereas nontherapeutic side effects, tumor microenvironment (TME) intricacy, and low tumor immunogenicity limit its therapeutic efficacy. In recent years, combination immunotherapy with other therapies has been proven to considerably increase antitumor efficacy. However, achieving codelivery of the drugs to the tumor site remains a major challenge. Stimulus‐responsive nanodelivery systems show controlled drug delivery and precise drug release. Polysaccharides, a family of potential biomaterials, are widely used in the development of stimulus‐responsive nanomedicines due to their unique physicochemical properties, biocompatibility, and modifiability. Here, the antitumor activity of polysaccharides and several combined immunotherapy strategies (e.g., immunotherapy combined with chemotherapy, photodynamic therapy, or photothermal therapy) are summarized. More importantly, the recent progress of polysaccharide‐based stimulus‐responsive nanomedicines for combination cancer immunotherapy is discussed, with the focus on construction of nanomedicine, targeted delivery, drug release, and enhanced antitumor effects. Finally, the limitations and application prospects of this new field are discussed.
Phase‐Inversion Induced 3D Electrode for Direct Acidic Electroreduction CO2 to Formic acid
Authors: Yan Tao , Pan Hui , Liu Zhikun , Kang Peng 
Published: March 2023

AbstractDirect electrochemical CO2 reduction to formic acid (FA) instead of formate is a challenging task due to the high acidity of FA and competitive hydrogen evolution reaction. Herein, 3D porous electrode (TDPE) is prepared by a simple phase inversion method, which can electrochemically reduce CO2 to FA in acidic conditions. Owing to interconnected channels, high porosity, and appropriate wettability, TDPE not only improves mass transport, but also realizes pH gradient to build higher local pH micro‐environment under acidic conditions for CO2 reduction compared with planar electrode and gas diffusion electrode. Kinetic isotopic effect experiments demonstrate that the proton transfer becomes the rate‐determining step at the pH of 1.8; however, not significant in neutral solution, suggesting that the proton is aiding the overall kinetics. Maximum FA Faradaic efficiency of 89.2% has been reached at pH 2.7 in a flow cell, generating FA concentration of 0.1 m. Integrating catalyst and gas–liquid partition layer into a single electrode structure by phase inversion method paves a facile avenue for direct production of FA by electrochemical CO2 reduction.
A Novel Aqueous Asymmetric Supercapacitor based on Pyrene‐4,5,9,10‐Tetraone Functionalized Graphene as the Cathode and Annealed Ti3C2Tx MXene as the Anode
Authors: Shi Mangmang , Peng Cheng , Zhang Xiaoyan 
Published: March 2023

AbstractAsymmetric supercapacitors (ASCs), employing two dissimilar electrode materials with a large redox peak position difference as cathode and anode, have been designed to further broaden the voltage window and improve the energy density of supercapacitors. Organic molecule based electrodes can be constructed by combining redox‐active organic molecules with conductive carbon‐based materials such as graphene. Herein, pyrene‐4,5,9,10‐tetraone (PYT), a redox‐active molecule with four carbonyl groups, exhibits a four‐electron transfer process and can potentially deliver a high capacity. PYT is noncovalently combined with two different kinds of graphene (Graphenea [GN] and LayerOne [LO]) at different mass ratios. The PYT‐functionalized GN electrode (PYT/GN 4–5) possesses a high capacity of 711 F g−1 at 1 A g−1 in 1 M H2SO4. To match with the PYT/GN 4–5 cathode, an annealed‐Ti3C2Tx (A‐Ti3C2Tx) MXene anode with a pseudocapacitive character is prepared by pyrolysis of pure Ti3C2Tx. The assembled PYT/GN 4–5//A‐Ti3C2Tx ASC delivers an outstanding energy density of 18.4 Wh kg−1 at a power density of 700 W kg−1. The PYT‐functionalized graphene holds great potential for high‐performance energy storage devices.
Materials and structural design for preferable Zn deposition behavior toward stable Zn anodes
Authors: Cao Qinghe , Gao Yong , Pu Jie , Elshahawy Abdelnaby M. , Guan Cao 
Published: March 2023

AbstractBenefiting from the high capacity of Zn metal anodes and intrinsic safety of aqueous electrolytes, rechargeable Zn ion batteries (ZIBs) show promising application in the post‐lithium‐ion period, exhibiting good safety, low cost, and high energy density. However, its commercialization still faces problems with low Coulombic efficiency and unsatisfied cycling performance due to the poor Zn/Zn2+ reversibility that occurred on the Zn anode. To improve the stability of the Zn anode, optimizing the Zn deposition behavior is an efficient way, which can enhance the subsequent striping efficiency and limit the dendrite growth. The Zn deposition is a controlled kinetics‐diffusion joint process that is affected by various factors, such as the interaction between Zn2+ ions and Zn anodes, ion concentration gradient, and current distribution. In this review, from an electrochemical perspective, we first overview the factors affecting the Zn deposition behavior and summarize the modification principles. Subsequently, strategies proposed for interfacial modification and 3D structural design as well as the corresponding mechanisms are summarized. Finally, the existing challenges, perspectives on further development direction, and outlook for practical applications of ZIBs are proposed.
Effect of high temperature on residual splitting strength of desert sand concrete
Authors: Yang Suhang , Zhang Lei , Xu Zhifeng 
Published: March 2023

AbstractThe ordinary medium sand can no longer meet the increasing demands of engineering projects. Construction costs can be reduced and the natural environment can be protected by rational use of the local desert sand. To evaluate the spalling and fire resistance of the concrete, the desert sand concrete (DSC) is heated to 100–800°C and then cooled for splitting tensile strength test. The test results indicate that with the increment of desert sand replacement rate (DSRR), the compressive strength of DSC increases first and then decreases. The maximum value is reached when DSRR is up to 40%. The presence of fly ash slows down the loss of splitting strength of concrete with the temperature increasing. The regression model is established to predict the functional relationship between the concrete splitting strength and temperatures under heating and air cooling conditions. The result shows that the predictions calculated by the formula are consistent with the experimental results. The formula can be employed as a constitutive relation of the computer model to evaluate the spalling and fire resistance of the DSC structure.
Performance of meta concrete panels subjected to explosive load: Numerical investigations
Authors: Nguyen‐Van Vuong , Peng Chenxi , Hazell Paul J. , Lee Jaehong , Nguyen‐Xuan H. , Tran Phuong 
Published: March 2023

AbstractResearch on strengthening and retrofitting of concrete structures against explosive loading has recently received much attention. This paper proposes a new type of reinforcement for concrete panels to enhance their blast‐resistant capacity. The reinforcement structure is naturally optimized with continuous nonself‐intersecting surfaces, known as triply periodic minimal surface (TPMS)‐primitive scaffold. A numerical model is developed to investigate the performance of TPMS‐primitive reinforced concrete panels against blast loading. The results are validated by experimental data from the literature on a traditional reinforced concrete slab. The concrete slabs reinforced with one, two, and four layers of TPMS‐primitive unit cells are designed and examined, while a quarter of the panel is simulated to reduce the computational cost. A constitutive model that considers the strain‐rate effect is employed to capture the rate‐dependent impulsive behavior of the proposed panels. The numerical results indicate significant enhancements in damage resistance and substantial reductions in deflection of the concrete reinforced panels when the TPMS‐primitive scaffold replaces the rebar lattice. The proposed reinforcement with multiple layers of unit cells retains high efficiency through parametric studies, while changes in the shell thickness of the reinforcement scaffold have limited effects on filtering blast waves.